Homology by BLASTX
BLASTX 2.2.4 [Aug-26-2002]
Query= B0261_2
(8094 letters)
Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
1,967,186 sequences; 661,712,633 total letters
Score E
Sequences producing significant alignments: (bits) Value
gi|41018240|sp|Q95Q95|TOR_CAEEL Target of rapamycin homolog (CeT... 5109 0.0
gi|32563905|ref|NP_491549.2| lethal protein 363 family member, L... 5089 0.0
gi|32563909|ref|NP_491552.2| lethal protein 363, LEThal LET-363 ... 5079 0.0
gi|39595871|emb|CAE67374.1| Hypothetical protein CBG12850 [Caeno... 2456 0.0
gi|4826730|ref|NP_004949.1| FK506 binding protein 12-rapamycin a... 1429 0.0
gi|744518|prf||2014422A FKBP-rapamycin-associated protein 1422 0.0
gi|3282239|gb|AAC39933.1| rapamycin associated protein FRAP2 [Ho... 1392 0.0
gi|9910228|ref|NP_064393.1| FK506 binding protein 12-rapamycin a... 1014 0.0
gi|9845251|ref|NP_063971.1| rapamycin and FKBP12 target-1 protei... 1013 0.0
gi|11136977|emb|CAC15570.1| rapamycin associated protein FRAP2 [... 940 0.0
gi|14530309|emb|CAC42395.1| dJ576K7.1 (FK506 binding protein 12-... 704 0.0
gi|40888981|gb|AAR97336.1| target of rapamycin [Aedes aegypti] 699 0.0
gi|17864562|ref|NP_524891.1| CG5092-PA [Drosophila melanogaster]... 698 0.0
gi|31225818|ref|XP_317619.1| ENSANGP00000007283 [Anopheles gambi... 695 0.0
gi|50759309|ref|XP_417614.1| PREDICTED: similar to FKBP-rapamyci... 694 0.0
gi|15292447|gb|AAK93492.1| SD02269p [Drosophila melanogaster] 677 0.0
gi|46127511|ref|XP_388309.1| hypothetical protein FG08133.1 [Gib... 639 0.0
gi|49097318|ref|XP_410119.1| hypothetical protein AN5982.2 [Aspe... 629 e-178
gi|47824786|emb|CAG30554.1| TorA protein [Emericella nidulans] 629 e-178
gi|19112151|ref|NP_595359.1| putative phosphatidylinositol-kinas... 629 e-178
gi|26400729|sp|Q9Y7K2|TOR2_SCHPO Phosphatidylinositol 3-kinase t... 629 e-178
gi|19113067|ref|NP_596275.1| putative phosphatidylinositol 3-kin... 625 e-177
gi|28569600|gb|AAO43977.1| Tor [Dictyostelium discoideum] 616 e-174
gi|32409965|ref|XP_325463.1| hypothetical protein [Neurospora cr... 610 e-172
gi|50304405|ref|XP_452152.1| unnamed protein product [Kluyveromy... 608 e-172
gi|45198938|ref|NP_985967.1| AFR420Wp [Eremothecium gossypii] >g... 601 e-170
gi|742559|prf||2010264B TOR2(DRR2) gene 600 e-169
gi|42759860|ref|NP_012719.2| putative protein/phosphatidylinosit... 599 e-169
gi|549092|sp|P32600|TOR2_YEAST Phosphatidylinositol 3-kinase TOR... 599 e-169
gi|49073198|ref|XP_400831.1| hypothetical protein UM03216.1 [Ust... 598 e-169
gi|46434639|gb|EAK94043.1| hypothetical protein CaO19.1903 [Cand... 597 e-168
gi|50287131|ref|XP_445995.1| unnamed protein product [Candida gl... 592 e-167
gi|22330143|ref|NP_175425.2| target of rapamycin protein (TOR) [... 591 e-166
gi|50555395|ref|XP_505106.1| hypothetical protein [Yarrowia lipo... 590 e-166
gi|50291629|ref|XP_448247.1| unnamed protein product [Candida gl... 587 e-165
gi|6322526|ref|NP_012600.1| Involved in cell cycle signaling and... 586 e-165
gi|468739|emb|CAA52849.1| TOR1 [Saccharomyces cerevisiae] 585 e-165
gi|4323242|gb|AAD16274.1| phosphatidylinositol 3-kinase TOR1 [Cr... 584 e-164
gi|50425533|ref|XP_461362.1| unnamed protein product [Debaryomyc... 582 e-164
gi|4323240|gb|AAD16273.1| phosphatidylinositol 3-kinase TOR1 [Cr... 582 e-164
gi|50257591|gb|EAL20296.1| hypothetical protein CNBF1080 [Crypto... 582 e-164
gi|408956|gb|AAB66881.1| mutant drr1-1 protein [Saccharomyces ce... 581 e-163
gi|25405349|pir||G96536 hypothetical protein F2J10.9 [imported] ... 569 e-160
gi|47222752|emb|CAG01719.1| unnamed protein product [Tetraodon n... 519 e-145
gi|17861886|gb|AAL39420.1| GM10438p [Drosophila melanogaster] 510 e-142
gi|806955|gb|AAB32956.1| RAPT1=putative novel phosphatidylinosit... 465 e-129
gi|7494076|pir||T14176 probable phosphatidylinositol 3 kinase - ... 445 e-123
gi|24181422|gb|AAM33436.1| phosphatidylinositol kinase-related k... 438 e-120
gi|29246072|gb|EAA37683.1| GLP_171_17599_22176 [Giardia lamblia ... 438 e-120
gi|47210569|emb|CAF94391.1| unnamed protein product [Tetraodon n... 387 e-105
gi|50255951|gb|EAL18680.1| hypothetical protein CNBI2680 [Crypto... 338 1e-90
gi|20260640|gb|AAM13218.1| unknown protein [Arabidopsis thaliana... 336 6e-90
gi|9366704|emb|CAB95466.1| phosphatidylinositol 3-kinase, probab... 300 3e-79
gi|46434641|gb|EAK94045.1| hypothetical protein CaO19.1905 [Cand... 236 5e-60
gi|31126780|gb|AAP44699.1| putative phosphatidylinositol 3-kinas... 236 9e-60
gi|24640238|ref|NP_727132.1| CG32743-PA [Drosophila melanogaster... 227 3e-57
gi|50257945|gb|EAL20642.1| hypothetical protein CNBE3070 [Crypto... 223 6e-56
gi|50755797|ref|XP_414907.1| PREDICTED: similar to PI-3-kinase A... 219 7e-55
gi|48098271|ref|XP_392036.1| similar to PI-3-kinase ATX [Apis me... 218 1e-54
gi|10120262|emb|CAC08177.1| TOR2 protein (target of rapamycin) [... 217 3e-54
gi|14289323|gb|AAK58892.1| LIP isoform of BLIP [Homo sapiens] 217 4e-54
gi|14719394|ref|NP_054725.1| PI-3-kinase-related kinase SMG-1 is... 217 4e-54
gi|16506130|dbj|BAB70696.1| phosphatidylinositol 3-kinase-relate... 217 4e-54
gi|18765739|ref|NP_055907.2| PI-3-kinase-related kinase SMG-1 is... 217 4e-54
gi|20521043|dbj|BAA24851.2| KIAA0421 [Homo sapiens] 217 4e-54
gi|21666440|gb|AAM73708.1| PI-3-kinase ATX [Homo sapiens] 217 4e-54
gi|49068872|ref|XP_398725.1| hypothetical protein UM01110.1 [Ust... 210 5e-52
gi|31203585|ref|XP_310741.1| ENSANGP00000021947 [Anopheles gambi... 206 6e-51
gi|11692798|gb|AAG40002.1| ataxia telangiectasia and Rad3-relate... 206 8e-51
gi|11385422|gb|AAG34794.1| Atr protein [Xenopus laevis] 205 2e-50
gi|1654096|emb|CAA70297.1| RAD3 [Schizosaccharomyces pombe] >gnl... 204 3e-50
gi|19112149|ref|NP_595357.1| rad3 checkpoint protein [Schizosacc... 204 3e-50
gi|38100260|gb|EAA47413.1| hypothetical protein MG02656.4 [Magna... 202 1e-49
gi|4502325|ref|NP_001175.1| ataxia telangiectasia and Rad3 relat... 201 3e-49
gi|1235902|gb|AAC50405.1| FRAP-related protein >gnl|BL_ORD_ID|30... 201 3e-49
gi|5825606|gb|AAD53316.1| UVSB [Aspergillus nidulans] 197 3e-48
gi|5853096|gb|AAD54313.1| UVSB PI-3 kinase [Emericella nidulans] 197 3e-48
gi|50731089|ref|XP_417160.1| PREDICTED: similar to ATM [Gallus g... 196 6e-48
gi|46128611|ref|XP_388859.1| hypothetical protein FG08683.1 [Gib... 196 6e-48
gi|47211480|emb|CAG13362.1| unnamed protein product [Tetraodon n... 196 8e-48
gi|38198590|emb|CAE53956.1| ataxia telangiectasia mutated [Danio... 196 1e-47
gi|46810446|gb|AAT01608.1| ataxia-telangiectasia mutated protein... 195 2e-47
gi|50423399|ref|XP_460282.1| unnamed protein product [Debaryomyc... 194 3e-47
gi|2304971|gb|AAB65827.1| ATM [Homo sapiens] 194 4e-47
gi|20336203|ref|NP_000042.2| ataxia telangiectasia mutated prote... 194 4e-47
gi|20336199|ref|NP_612149.1| ataxia telangiectasia mutated prote... 194 4e-47
gi|13878337|sp|Q13315|ATM_HUMAN Serine-protein kinase ATM (Ataxi... 193 5e-47
gi|1585222|prf||2124355A ATM gene 193 5e-47
gi|1497931|gb|AAB38309.1| ataxia-telangiectasia 193 5e-47
gi|1082236|pir||A43100 ataxia telangiectasia-associated protein ... 193 5e-47
gi|7288126|dbj|BAA92828.1| AtRAD3 [Arabidopsis thaliana] 193 7e-47
gi|18422029|ref|NP_198898.2| FAT domain-containing protein / pho... 193 7e-47
gi|45595560|gb|AAH67212.1| Atm protein [Mus musculus] 192 9e-47
gi|6680740|ref|NP_031525.1| ataxia telangiectasia mutated homolo... 192 9e-47
gi|50285547|ref|XP_445202.1| unnamed protein product [Candida gl... 192 1e-46
gi|10177961|dbj|BAB11344.1| AtRAD3 [Arabidopsis thaliana] 191 2e-46
gi|6636413|gb|AAF20175.1| ataxia telangiectasia mutated [Xenopus... 190 4e-46
gi|39595784|emb|CAE67287.1| Hypothetical protein CBG12735 [Caeno... 189 7e-46
gi|31239405|ref|XP_320116.1| ENSANGP00000018055 [Anopheles gambi... 189 1e-45
gi|46226870|gb|EAK87836.1| FRP1 like protein involved in DNA rep... 188 2e-45
gi|45125076|emb|CAD89223.1| SMG1 protein [Drosophila melanogaster] 188 2e-45
gi|46431886|gb|EAK91407.1| hypothetical protein CaO19.8870 [Cand... 187 3e-45
gi|46431896|gb|EAK91416.1| hypothetical protein CaO19.1283 [Cand... 187 3e-45
gi|32408649|ref|XP_324805.1| hypothetical protein [Neurospora cr... 187 4e-45
gi|50418747|ref|XP_457893.1| unnamed protein product [Debaryomyc... 187 4e-45
gi|49103003|ref|XP_411112.1| hypothetical protein AN6975.2 [Aspe... 187 5e-45
gi|11357182|pir||T51174 ataxia-telangiectasia mutated protein (A... 186 6e-45
gi|6045181|dbj|BAA85312.1| ataxia telangiectasia mutated [Gallus... 186 6e-45
gi|6319612|ref|NP_009694.1| Central regulator of the Mec1p/Tel1p... 186 8e-45
gi|950173|gb|AAA74482.1| Mec1p 186 8e-45
gi|506876|dbj|BAA01860.1| Esr1 protein [Saccharomyces cerevisiae] 186 8e-45
gi|7960715|emb|CAB92122.1| AtATM [Arabidopsis thaliana] 186 8e-45
gi|7497597|pir||T28923 hypothetical protein C48B6.6 - Caenorhabd... 184 2e-44
gi|25150275|ref|NP_491970.2| suppressor with Morphological effec... 184 2e-44
gi|45185338|ref|NP_983055.1| ABR108Cp [Eremothecium gossypii] >g... 181 2e-43
gi|47208584|emb|CAF90921.1| unnamed protein product [Tetraodon n... 181 3e-43
gi|11761138|dbj|BAA36690.1| DNA-dependent protein kinase catalyt... 178 2e-42
gi|2749954|gb|AAC60340.1| DNA-dependent protein kinase [Xenopus ... 178 2e-42
gi|21063935|gb|AAM29197.1| AT01448p [Drosophila melanogaster] 176 6e-42
gi|50556528|ref|XP_505672.1| hypothetical protein [Yarrowia lipo... 176 6e-42
gi|46122283|ref|XP_385695.1| hypothetical protein FG05519.1 [Gib... 176 8e-42
gi|50305889|ref|XP_452905.1| unnamed protein product [Kluyveromy... 176 8e-42
gi|46441069|gb|EAL00369.1| hypothetical protein CaO19.13026 [Can... 176 1e-41
gi|46440946|gb|EAL00247.1| hypothetical protein CaO19.5580 [Cand... 176 1e-41
gi|24647031|ref|NP_650435.1| CG6535-PA [Drosophila melanogaster]... 175 1e-41
gi|40743853|gb|AAR89513.1| ATM protein [Drosophila melanogaster] 175 1e-41
gi|38099189|gb|EAA46567.1| hypothetical protein MG08910.4 [Magna... 172 1e-40
gi|23956060|ref|NP_035289.1| protein kinase, DNA activated, cata... 172 2e-40
gi|3241856|dbj|BAA28873.1| DNA-dependent protein kinase catalyti... 172 2e-40
gi|49083858|ref|XP_404175.1| hypothetical protein AN0038.2 [Aspe... 171 2e-40
gi|24642511|ref|NP_523369.2| CG4252-PA [Drosophila melanogaster]... 171 3e-40
gi|19075626|ref|NP_588126.1| phosphotidylinositol kinase, tel1p;... 171 3e-40
gi|7511960|pir||T13288 mei-41 protein - fruit fly (Drosophila me... 171 3e-40
gi|20334955|dbj|BAB91148.1| DNA-dependent protein kinase catalyt... 168 2e-39
gi|598227|gb|AAC41713.1| RAPT1 [Homo sapiens] >gnl|BL_ORD_ID|137... 168 2e-39
gi|45382811|ref|NP_989989.1| DNA-dependent protein kinase cataly... 168 2e-39
gi|45200810|ref|NP_986380.1| AGL287Wp [Eremothecium gossypii] >g... 168 2e-39
gi|47212122|emb|CAG06224.1| unnamed protein product [Tetraodon n... 168 2e-39
gi|50308521|ref|XP_454263.1| unnamed protein product [Kluyveromy... 167 4e-39
gi|17646639|gb|AAL40979.1| DNA-dependent protein kinase catalyti... 162 1e-37
gi|32403494|ref|XP_322360.1| hypothetical protein [Neurospora cr... 162 1e-37
gi|586447|sp|P38110|TEL1_YEAST Telomer length regulation protein... 161 3e-37
gi|6319383|ref|NP_009465.1| Protein kinase, primarily involved i... 161 3e-37
gi|17646641|gb|AAL40980.1| DNA-dependent protein kinase catalyti... 159 1e-36
gi|19074032|ref|NP_584638.1| PROTEIN KINASE OF THE PI3/PI4 FAMIL... 159 1e-36
gi|50549817|ref|XP_502380.1| hypothetical protein [Yarrowia lipo... 159 1e-36
gi|13654237|ref|NP_008835.5| protein kinase, DNA-activated, cata... 157 5e-36
gi|13936336|gb|AAK40350.1| DNA-dependent protein kinase [Homo sa... 157 5e-36
gi|7512396|pir||G02083 DNA-PK - human (fragment) >gnl|BL_ORD_ID|... 156 9e-36
gi|50289131|ref|XP_446995.1| unnamed protein product [Candida gl... 154 3e-35
gi|1747318|dbj|BAA12115.1| mDNApk3' [Mus musculus] 152 2e-34
gi|26354110|dbj|BAC40685.1| unnamed protein product [Mus musculus] 152 2e-34
gi|50257481|gb|EAL20188.1| hypothetical protein CNBF2640 [Crypto... 149 1e-33
gi|13606056|gb|AAC50210.3| DNA dependent protein kinase catalyti... 147 4e-33
gi|1362789|pir||A57099 DNA-activated protein kinase, catalytic s... 147 5e-33
gi|33944353|ref|XP_340324.1| phosphatidylinositol 3-kinase, puta... 145 1e-32
gi|7385181|gb|AAF61728.1| protein kinase ATR [Mus musculus] 144 4e-32
gi|34870011|ref|XP_341021.1| similar to DNA-dependent protein ki... 136 7e-30
gi|46431140|gb|EAK90769.1| hypothetical protein CaO19.1018 [Cand... 134 3e-29
gi|31230620|ref|XP_318419.1| ENSANGP00000002762 [Anopheles gambi... 131 3e-28
gi|4001813|gb|AAC94996.1| putative FKBP12-rapamycin associated p... 131 3e-28
gi|38090005|ref|XP_147046.2| similar to ataxia telangiectasia an... 129 9e-28
gi|28850398|gb|AAO53167.1| similar to Homo sapiens (Human). KIAA... 129 9e-28
gi|34894104|ref|NP_908377.1| AtATM like protein [Oryza sativa (j... 128 3e-27
gi|39594638|emb|CAE72216.1| Hypothetical protein CBG19327 [Caeno... 127 3e-27
gi|48107163|ref|XP_396177.1| similar to ataxia telangiectasia mu... 127 3e-27
gi|40215825|gb|AAR82784.1| LD17186p [Drosophila melanogaster] 124 4e-26
gi|6434317|emb|CAA94790.2| Hypothetical protein T06E4.3a [Caenor... 123 7e-26
gi|7507297|pir||T24588 hypothetical protein T06E4.3 - Caenorhabd... 123 7e-26
gi|25151810|ref|NP_505487.2| ataxia Telangectasia mutated ATM-Li... 123 7e-26
gi|25145564|ref|NP_490693.2| ataxia Telangectasia Mutated relate... 116 8e-24
gi|34866753|ref|XP_346006.1| similar to ataxia telangiectasia an... 116 1e-23
gi|34863403|ref|XP_236275.2| similar to homolog of the human ata... 115 1e-23
gi|39589278|emb|CAE74307.1| Hypothetical protein CBG22015 [Caeno... 114 3e-23
gi|3891580|pdb|1AUE|A Chain A, Fkbp-Rapamycin Binding Domain (Fr... 108 2e-21
gi|2392329|pdb|1FAP|B Chain B, The Structure Of The Immunophilin... 102 1e-19
gi|2981800|pdb|1NSG|B Chain B, The Structure Of The Immunophilin... 101 3e-19
gi|50751972|ref|XP_422595.1| PREDICTED: similar to ataxia telang... 96 1e-17
gi|27696764|gb|AAH43920.1| Similar to FK506 binding protein 12-r... 95 2e-17
gi|50284843|ref|XP_444849.1| unnamed protein product [Candida gl... 93 1e-16
gi|4507691|ref|NP_003487.1| transformation/transcription domain-... 90 8e-16
gi|38605529|sp|Q9Y4A5|TRAP_HUMAN Transformation/transcription do... 90 8e-16
gi|6321891|ref|NP_011967.1| TRA1 is the homolog of the human pro... 90 1e-15
gi|50058072|gb|AAT68901.1| Suppressor with morphological effect ... 90 1e-15
gi|29246070|gb|EAA37681.1| GLP_171_12484_15798 [Giardia lamblia ... 86 1e-14
gi|38605208|sp|Q80YV3|TRAP_MOUSE Transformation/transcription do... 85 3e-14
gi|20809434|gb|AAH29023.1| Unknown (protein for MGC:32458) [Mus ... 85 3e-14
gi|50755457|ref|XP_414752.1| PREDICTED: similar to transformatio... 82 2e-13
gi|34865788|ref|XP_236563.2| similar to ataxia telangiectasia an... 82 2e-13
gi|19113774|ref|NP_592862.1| TRAP-like protein [Schizosaccharomy... 80 6e-13
gi|3694663|gb|AAC62433.1| similar to hypothetical proteins P3881... 75 3e-11
gi|1688254|gb|AAB36939.1| DNA-dependent protein kinase [Mus musc... 75 3e-11
gi|31213179|ref|XP_315533.1| ENSANGP00000007163 [Anopheles gambi... 75 3e-11
gi|49116376|ref|XP_412137.1| hypothetical protein AN8000.2 [Aspe... 74 5e-11
gi|15227924|ref|NP_179383.1| FAT domain-containing protein / pho... 74 5e-11
gi|45190994|ref|NP_985248.1| AER393Cp [Eremothecium gossypii] >g... 74 8e-11
gi|47226083|emb|CAG04457.1| unnamed protein product [Tetraodon n... 73 1e-10
gi|50307787|ref|XP_453887.1| unnamed protein product [Kluyveromy... 72 2e-10
gi|4160337|emb|CAA22805.1| SPBC646.01c [Schizosaccharomyces pombe] 72 2e-10
gi|32412784|ref|XP_326872.1| related to the component Tra1 of th... 72 3e-10
gi|1688256|gb|AAB36940.1| DNA-dependent protein kinase [Mus musc... 72 3e-10
gi|7487184|pir||T05501 hypothetical protein T19K4.210 - Arabidop... 71 4e-10
gi|22329206|ref|NP_680770.1| FAT domain-containing protein / pho... 71 4e-10
gi|25407720|pir||C85426 ATM-like protein [imported] - Arabidopsi... 71 4e-10
gi|5453189|gb|AAD43472.1| phosphatidylinositol 3-kinase Pdd1p [P... 70 7e-10
gi|46438375|gb|EAK97707.1| hypothetical protein CaO19.10955 [Can... 70 1e-09
gi|46123423|ref|XP_386265.1| hypothetical protein FG06089.1 [Gib... 69 2e-09
gi|26325354|dbj|BAC26431.1| unnamed protein product [Mus musculus] 69 2e-09
gi|16944583|emb|CAC18279.2| related to the component Tra1 of the... 69 2e-09
gi|3688225|emb|CAA09718.1| phosphatidylinositol 4-kinase [Candid... 69 2e-09
gi|5771512|gb|AAD51410.1| unknown [Candida albicans] >gnl|BL_ORD... 69 2e-09
gi|48098127|ref|XP_393981.1| similar to ENSANGP00000007163 [Apis... 69 2e-09
gi|31236716|ref|XP_319464.1| ENSANGP00000002906 [Anopheles gambi... 68 3e-09
gi|50547759|ref|XP_501349.1| hypothetical protein [Yarrowia lipo... 68 4e-09
gi|50312067|ref|XP_456065.1| unnamed protein product [Kluyveromy... 67 6e-09
gi|6323269|ref|NP_013341.1| phosphatidylinositol 3-kinase; Vps34... 67 9e-09
gi|19112569|ref|NP_595777.1| putative phosphatidylinositol kinas... 67 9e-09
gi|26375641|dbj|BAB27985.2| unnamed protein product [Mus musculus] 66 2e-08
gi|17567531|ref|NP_510529.1| 2 polypeptide (XP854) [Caenorhabdit... 65 3e-08
gi|12622090|gb|AAB92360.2| DNA protein kinase catalytic subunit ... 65 3e-08
gi|46440622|gb|EAK99926.1| hypothetical protein CaO19.6243 [Cand... 65 4e-08
gi|38100735|gb|EAA47826.1| hypothetical protein MG03069.4 [Magna... 65 4e-08
gi|49093908|ref|XP_408415.1| hypothetical protein AN4278.2 [Aspe... 65 4e-08
gi|50259960|gb|EAL22626.1| hypothetical protein CNBB2580 [Crypto... 64 5e-08
gi|19115611|ref|NP_594699.1| phosphatidylinositol 3-kinase vps34... 64 5e-08
gi|25751343|pir||T52538 1-phosphatidylinositol 3-kinase (EC 2.7.... 64 5e-08
gi|50603967|gb|AAH77528.1| Unknown (protein for MGC:83282) [Xeno... 64 6e-08
gi|46440531|gb|EAK99836.1| hypothetical protein CaO19.13621 [Can... 64 8e-08
gi|46108558|ref|XP_381337.1| hypothetical protein FG01161.1 [Gib... 64 8e-08
gi|27552468|emb|CAD56881.1| phosphatidylinositol 3-kinase [Medic... 64 8e-08
gi|1730568|sp|P54677|PI4K_DICDI Phosphatidylinositol 4-kinase (P... 64 8e-08
gi|45200984|ref|NP_986554.1| AGL113Cp [Eremothecium gossypii] >g... 63 1e-07
gi|1076903|pir||PC4002 phosphatidylinositol-3 kinase (EC 3.1.3.-... 63 1e-07
gi|31204385|ref|XP_311141.1| ENSANGP00000020426 [Anopheles gambi... 63 1e-07
gi|1171966|sp|P42348|P3K2_SOYBN Phosphatidylinositol 3-kinase, n... 63 1e-07
gi|2499560|sp|Q92213|VP34_CANAL Phosphatidylinositol 3-kinase VP... 62 2e-07
gi|50427021|ref|XP_462115.1| unnamed protein product [Debaryomyc... 62 3e-07
gi|1171965|sp|P42347|P3K1_SOYBN Phosphatidylinositol 3-kinase, r... 62 3e-07
gi|32423243|ref|XP_332059.1| hypothetical protein [Neurospora cr... 61 4e-07
gi|21356197|ref|NP_650902.1| CG4141-PA [Drosophila melanogaster]... 61 4e-07
gi|50260410|gb|EAL23067.1| hypothetical protein CNBA5920 [Crypto... 61 4e-07
gi|23613175|ref|NP_703497.1| phosphatidylinositol 3-kinase, puta... 61 5e-07
gi|7484352|pir||T08420 1-phosphatidylinositol 3-kinase (EC 2.7.1... 60 7e-07
gi|39596671|emb|CAE63290.1| Hypothetical protein CBG07670 [Caeno... 60 9e-07
gi|38107628|gb|EAA53773.1| hypothetical protein MG09523.4 [Magna... 60 9e-07
gi|23491282|gb|EAA22859.1| phosphatidylinositol 3-kinase vps34-l... 59 2e-06
gi|50288595|ref|XP_446727.1| unnamed protein product [Candida gl... 59 2e-06
gi|29249882|gb|EAA41385.1| GLP_630_45311_38844 [Giardia lamblia ... 59 2e-06
gi|19074845|ref|NP_586351.1| PHOSPHATIDYLINOSITOL 4-KINASE (C-te... 58 3e-06
gi|45187841|ref|NP_984064.1| ADL033Wp [Eremothecium gossypii] >g... 58 3e-06
gi|50422459|ref|XP_459796.1| DhPIK1 [Debaryomyces hansenii] >gnl... 58 4e-06
gi|50554169|ref|XP_504493.1| hypothetical protein [Yarrowia lipo... 58 4e-06
gi|1362886|pir||S57219 1-phosphatidylinositol 3-kinase (EC 2.7.1... 58 4e-06
gi|987948|emb|CAA87094.1| phosphatidylinositol 3-kinase [Homo sa... 58 4e-06
gi|47224849|emb|CAG06419.1| unnamed protein product [Tetraodon n... 57 6e-06
gi|50306023|ref|XP_452973.1| unnamed protein product [Kluyveromy... 57 6e-06
gi|50286513|ref|XP_445685.1| unnamed protein product [Candida gl... 57 7e-06
gi|19353278|gb|AAH24675.1| Pik3c3 protein [Mus musculus] 57 7e-06
gi|41055186|ref|NP_957493.1| similar to phosphoinositide-3-kinas... 57 7e-06
gi|29250954|gb|EAA42440.1| GLP_587_305_8206 [Giardia lamblia ATC... 57 7e-06
gi|42475974|ref|NP_852079.2| phosphoinositide-3-kinase, class 3 ... 57 7e-06
gi|12621140|ref|NP_075247.1| phosphatidylinositol 3-kinase; PI-3... 57 7e-06
gi|34761064|ref|NP_002638.2| phosphoinositide-3-kinase, class 3;... 57 7e-06
gi|1709528|sp|P54676|P3K4_DICDI Phosphatidylinositol 3-kinase VP... 57 7e-06
gi|28144171|gb|AAO26044.1| ataxia telangiectasia mutated (includ... 57 1e-05
gi|46431626|gb|EAK91167.1| hypothetical protein CaO19.9377 [Cand... 56 1e-05
gi|46431631|gb|EAK91171.1| hypothetical protein CaO19.1814 [Cand... 56 1e-05
gi|49119578|gb|AAH73706.1| Unknown (protein for MGC:83640) [Xeno... 56 2e-05
gi|34859032|ref|XP_341912.1| similar to phosphoinositide 3-kinas... 56 2e-05
gi|46128289|ref|XP_388698.1| hypothetical protein FG08522.1 [Gib... 56 2e-05
gi|47228805|emb|CAG07537.1| unnamed protein product [Tetraodon n... 56 2e-05
gi|19115754|ref|NP_594842.1| putative phosphatidylinositol 4-kin... 56 2e-05
gi|47210567|emb|CAF94389.1| unnamed protein product [Tetraodon n... 55 2e-05
gi|12833769|dbj|BAB22657.1| unnamed protein product [Mus musculus] 55 2e-05
gi|29789235|ref|NP_083370.1| phosphatidylinositol 3-kinase, cata... 55 2e-05
gi|4505799|ref|NP_002636.1| phosphoinositide-3-kinase, class 2, ... 55 3e-05
gi|17567491|ref|NP_508177.1| phosphatidylinositol (XB538) [Caeno... 55 3e-05
gi|11259849|pir||T42642 phosphoinositide 3-kinase (EC 2.7.1.-) -... 55 3e-05
gi|6323336|ref|NP_013408.1| functions in the PKC1 protein kinase... 55 3e-05
gi|45199185|ref|NP_986214.1| AFR666Cp [Eremothecium gossypii] >g... 55 3e-05
gi|2340969|gb|AAB67354.1| Stt4p: phosphatidylinositol-4-kinase [... 55 3e-05
gi|5771504|gb|AAD51405.1| PIKa [Candida albicans] >gnl|BL_ORD_ID... 55 4e-05
gi|26334015|dbj|BAC30725.1| unnamed protein product [Mus musculus] 55 4e-05
gi|6679319|ref|NP_032866.1| phosphatidylinositol 3-kinase cataly... 55 4e-05
gi|22758919|gb|AAN05615.1| phosphoinositide 3 kinase P110delta [... 55 4e-05
gi|39583262|emb|CAE60054.1| Hypothetical protein CBG03566 [Caeno... 55 4e-05
gi|32408711|ref|XP_324836.1| hypothetical protein [Neurospora cr... 55 4e-05
gi|17556524|ref|NP_499596.1| type 3 phosphatidylinositol (3N342)... 55 4e-05
gi|37515284|gb|AAH35203.2| Phosphatidylinositol 3-kinase catalyt... 55 4e-05
gi|2076751|gb|AAB53966.1| phosphatidylinositol 3-kinase delta ca... 55 4e-05
gi|34872607|ref|XP_345607.1| similar to Phosphatidylinositol-4,5... 55 4e-05
gi|16758236|ref|NP_445933.1| phosphatidylinositol 3-kinase, cata... 55 4e-05
gi|17933718|ref|NP_524822.1| CG7004-PA [Drosophila melanogaster]... 54 5e-05
gi|6691825|emb|CAB65858.1| EG:BACR7C10.2 [Drosophila melanogaster] 54 5e-05
gi|39592522|emb|CAE63599.1| Hypothetical protein CBG08090 [Caeno... 54 5e-05
gi|23397467|ref|NP_570014.2| CG10260-PB [Drosophila melanogaster... 54 5e-05
gi|47227919|emb|CAF97548.1| unnamed protein product [Tetraodon n... 54 5e-05
gi|24654710|ref|NP_728519.1| CG7004-PC [Drosophila melanogaster]... 54 5e-05
gi|21064847|gb|AAM29653.1| SD12145p [Drosophila melanogaster] 54 5e-05
gi|50759285|ref|XP_417602.1| PREDICTED: similar to phosphoinosit... 54 6e-05
gi|19112096|ref|NP_595304.1| putative phosphatidylinositol 4-kin... 54 6e-05
gi|1786094|gb|AAB41106.1| putative phosphatidylinositol 3-kinase... 54 6e-05
gi|33304015|gb|AAQ02515.1| phosphoinositide-3-kinase, catalytic,... 54 8e-05
gi|13097276|gb|AAH03393.1| Unknown (protein for IMAGE:3447173) [... 54 8e-05
gi|42733896|gb|AAS38812.1| similar to Homo sapiens (Human). Phos... 54 8e-05
gi|6755058|ref|NP_035213.1| phosphatidylinositol 3-kinase, C2 do... 54 8e-05
gi|5453894|ref|NP_006210.1| phosphoinositide-3-kinase, catalytic... 54 8e-05
gi|11259838|pir||T43628 phosphatidylinositol 3-kinase homolog - ... 53 1e-04
gi|47206233|emb|CAF91363.1| unnamed protein product [Tetraodon n... 53 1e-04
gi|7494717|pir||T25442 hypothetical protein B0025.1 - Caenorhabd... 53 1e-04
gi|6671486|gb|AAF23185.1| Related to yeast vacuolar protein sort... 53 1e-04
gi|12652575|gb|AAH00029.1| PIK4CB protein [Homo sapiens] >gnl|BL... 53 1e-04
gi|1894947|gb|AAC51156.1| PtdIns 4-kinase [Homo sapiens] 53 1e-04
gi|4505809|ref|NP_002642.1| phosphatidylinositol 4-kinase, catal... 53 1e-04
gi|39589346|emb|CAE74375.1| Hypothetical protein CBG22101 [Caeno... 53 1e-04
gi|19923289|ref|NP_005017.2| phosphoinositide-3-kinase, catalyti... 53 1e-04
gi|37496959|emb|CAA71149.2| phosphoinositide 3-kinase [Homo sapi... 53 1e-04
gi|3024334|sp|O00329|P11D_HUMAN Phosphatidylinositol-4,5-bisphos... 53 1e-04
gi|33303741|gb|AAQ02384.1| phosphatidylinositol 4-kinase, cataly... 53 1e-04
gi|15077853|gb|AAK83379.1| phosphatidylinositol 3-kinase alpha c... 53 1e-04
gi|38372507|sp|Q9UBF8|P4KB_HUMAN Phosphatidylinositol 4-kinase b... 53 1e-04
gi|50747824|ref|XP_421003.1| PREDICTED: similar to phosphoinosit... 53 1e-04
gi|17509429|ref|NP_491741.1| related to yeast Vacuolar Protein S... 53 1e-04
gi|6679317|ref|NP_032865.1| phosphatidylinositol 3-kinase, catal... 53 1e-04
gi|31231338|ref|XP_318507.1| ENSANGP00000021188 [Anopheles gambi... 53 1e-04
gi|47207889|emb|CAF89996.1| unnamed protein product [Tetraodon n... 53 1e-04
gi|32398757|emb|CAD98717.1| phosphatidylinositol kinase-like pro... 53 1e-04
gi|31198835|ref|XP_308365.1| ENSANGP00000009420 [Anopheles gambi... 53 1e-04
gi|31198303|ref|XP_308099.1| ENSANGP00000019761 [Anopheles gambi... 53 1e-04
gi|33304049|gb|AAQ02532.1| phosphoinositide-3-kinase, catalytic,... 53 1e-04
gi|24711346|gb|AAN62481.1| phosphatidylinositol 3-kinase [Brassi... 53 1e-04
gi|555700|gb|AAA83427.1| phosphatidylinositol 3-kinase 53 1e-04
gi|49077354|ref|XP_402546.1| hypothetical protein UM04931.1 [Ust... 53 1e-04
gi|1763626|gb|AAB39753.1| phosphoinositide 3'-hydroxykinase p110... 53 1e-04
gi|5453892|ref|NP_006209.1| phosphoinositide-3-kinase, catalytic... 53 1e-04
gi|27807037|ref|NP_776999.1| phosphoinositide-3-kinase, catalyti... 53 1e-04
gi|2245503|gb|AAB62532.1| gag-v-phosphoinositide 3-kinase cataly... 53 1e-04
gi|7511986|pir||T13801 phosphoinositide 3-kinase (EC 2.7.-.-) - ... 52 2e-04
gi|1272420|gb|AAC47117.1| phosphoinositide 3-kinase [Drosophila ... 52 2e-04
gi|24662891|ref|NP_524028.2| CG11621-PA [Drosophila melanogaster... 52 2e-04
gi|39597255|emb|CAE59483.1| Hypothetical protein CBG02868 [Caeno... 52 2e-04
gi|46229113|gb|EAK89962.1| membrane associated protein with 2 tr... 52 2e-04
gi|15237610|ref|NP_201212.1| phosphatidylinositol 4-kinase (PI4K... 52 2e-04
gi|25453507|pir||T52631 1-phosphatidylinositol 4-kinase (EC 2.7.... 52 2e-04
gi|49067556|ref|XP_398068.1| hypothetical protein UM00453.1 [Ust... 52 2e-04
gi|50752070|ref|XP_422639.1| PREDICTED: similar to Phosphatidyli... 52 2e-04
gi|15219743|ref|NP_176251.1| phosphatidylinositol 3-kinase (PI3K... 52 2e-04
gi|32398915|emb|CAD98380.1| PI3_PI4_kinase, possible [Cryptospor... 52 2e-04
gi|19347828|gb|AAL86326.1| putative phosphatidylinositol 3-kinas... 52 2e-04
gi|50304695|ref|XP_452303.1| unnamed protein product [Kluyveromy... 52 3e-04
gi|50752436|ref|XP_422779.1| PREDICTED: similar to phosphoinosit... 52 3e-04
gi|34864270|ref|XP_234053.2| similar to phosphatidylinositol 3-k... 52 3e-04
gi|38605332|sp|Q8I8U7|TRA1_DROME Transcription-associated protei... 52 3e-04
gi|20129711|ref|NP_610161.1| CG2905-PA [Drosophila melanogaster]... 52 3e-04
gi|1850329|gb|AAC47459.1| AGE-1 [Caenorhabditis elegans] 51 4e-04
gi|7649667|emb|CAB88874.1| phosphatidylinositol 4-kinase [Solanu... 51 4e-04
gi|7489248|pir||T07007 probable 1-phosphatidylinositol 4-kinase ... 51 4e-04
gi|26324936|dbj|BAC26222.1| unnamed protein product [Mus musculus] 51 4e-04
gi|29648332|ref|NP_780565.1| phosphatidylinositol 4-kinase, cata... 51 4e-04
gi|14389295|ref|NP_112345.1| phosphatidylinositol 4-kinase b [Ra... 51 4e-04
gi|50806186|ref|XP_428802.1| PREDICTED: similar to phosphoinosit... 51 5e-04
gi|11513658|pdb|1E8Y|A Chain A, Structure Determinants Of Phosph... 50 7e-04
gi|15242394|ref|NP_196497.1| phosphatidylinositol 4-kinase, puta... 50 7e-04
gi|13096755|pdb|1HE8|A Chain A, Ras G12v - Pi 3-Kinase Gamma Com... 50 7e-04
gi|9955522|emb|CAC05461.1| putative protein [Arabidopsis thaliana] 50 7e-04
gi|2135918|pir||A57134 1-phosphatidylinositol 3-kinase (EC 2.7.1... 50 7e-04
gi|1709513|sp|P48736|P11G_HUMAN Phosphatidylinositol-4,5-bisphos... 50 7e-04
gi|27807505|ref|NP_777208.1| phosphatidylinositol 4-kinase, cata... 50 7e-04
gi|21237725|ref|NP_002640.2| phosphoinositide-3-kinase, catalyti... 50 7e-04
gi|12620871|gb|AAG61115.1| phosphoinositide-3-kinase gamma catal... 50 7e-04
gi|38372429|sp|O02810|P4KB_BOVIN Phosphatidylinositol 4-kinase b... 50 7e-04
gi|47213737|emb|CAF96098.1| unnamed protein product [Tetraodon n... 50 0.001
gi|48112409|ref|XP_396329.1| similar to ataxia telangiectasia mu... 50 0.001
gi|48138217|ref|XP_396869.1| similar to ENSANGP00000019761 [Apis... 50 0.001
gi|50291259|ref|XP_448062.1| unnamed protein product [Candida gl... 50 0.001
gi|47204186|emb|CAG13549.1| unnamed protein product [Tetraodon n... 50 0.001
gi|33358197|pdb|1E7V|A Chain A, Structure Determinants Of Phosph... 50 0.001
gi|11513657|pdb|1E8X|A Chain A, Structural Insights Into Phoshoi... 50 0.001
gi|12084791|pdb|1E7U|A Chain A, Structure Determinants Of Phosph... 50 0.001
gi|47522612|ref|NP_999104.1| catalytic subunit of G-beta-gamma-a... 50 0.001
gi|29249411|gb|EAA40923.1| GLP_186_22597_27513 [Giardia lamblia ... 49 0.002
gi|47213156|emb|CAF93846.1| unnamed protein product [Tetraodon n... 49 0.002
gi|49080384|ref|XP_403718.1| hypothetical protein UM06103.1 [Ust... 49 0.002
gi|7511517|pir||S71792 phosphatidylinositol-3-OH kinase AGE-1 - ... 49 0.002
gi|17531311|ref|NP_496462.1| AGEing alteration AGE-1, abnormal D... 49 0.002
gi|50256377|gb|EAL19102.1| hypothetical protein CNBH2020 [Crypto... 49 0.003
gi|47178217|emb|CAG13772.1| unnamed protein product [Tetraodon n... 49 0.003
gi|20796713|emb|CAC81902.1| phophatdylinositol 4-kinase [Oryza s... 49 0.003
gi|50545769|ref|XP_500423.1| hypothetical protein [Yarrowia lipo... 49 0.003
gi|23613121|ref|NP_703443.1| phosphatidylinositol 4-kinase, puta... 49 0.003
gi|23478881|gb|EAA15852.1| phosphatidylinositol 4-kinase-related... 49 0.003
gi|6979325|gb|AAF34418.1| putative phosphatidylinositol 4-kinase... 49 0.003
gi|50416360|gb|AAH77604.1| Unknown (protein for MGC:84514) [Xeno... 48 0.005
gi|4758924|ref|NP_004561.1| phosphoinositide-3-kinase, class 2, ... 48 0.005
gi|7434342|pir||PC4348 phosphoinositide 3-kinase (EC 2.7.-.-) T1... 48 0.005
gi|50404944|ref|YP_054036.1| Phosphatidylinositol 4-kinase, puta... 48 0.005
gi|50756213|ref|XP_415062.1| PREDICTED: similar to phosphatidyli... 47 0.006
gi|32425423|gb|AAH18120.2| PIK4CA protein [Homo sapiens] 47 0.006
gi|30584637|gb|AAP36571.1| Homo sapiens phosphatidylinositol 4-k... 47 0.006
gi|7434348|pir||PC4345 phosphoinositide 3-kinase (EC 2.7.-.-) T9... 47 0.006
gi|17105400|ref|NP_477352.1| phosphatidylinositol 4-kinase, cata... 47 0.006
gi|50233838|ref|NP_001001983.1| phosphatidylinositol 4-kinase, c... 47 0.006
gi|4505807|ref|NP_002641.1| phosphatidylinositol 4-kinase, catal... 47 0.006
gi|25742825|ref|NP_071637.1| phosphatidylinositol 4-kinase a [Ra... 47 0.006
gi|29351621|gb|AAH49252.1| Pik4ca protein [Mus musculus] 47 0.006
gi|6525041|gb|AAF15300.1| phosphoinositide 3 kinase catalytic su... 47 0.006
gi|33585469|gb|AAH55479.1| Pik4ca protein [Mus musculus] 47 0.006
gi|18044951|gb|AAH20225.1| LOC220686 protein [Homo sapiens] 47 0.006
gi|34015227|gb|AAQ56420.1| putative kinase [Oryza sativa (japoni... 47 0.008
gi|29246071|gb|EAA37682.1| GLP_171_15785_17266 [Giardia lamblia ... 47 0.008
gi|50256750|gb|EAL19470.1| hypothetical protein CNBG4170 [Crypto... 47 0.008
gi|17137150|ref|NP_477133.1| CG5373-PA [Drosophila melanogaster]... 47 0.008
gi|1854505|emb|CAA68185.1| 1-phosphatidylinositol 3-kinase [Dros... 47 0.008
gi|16758806|ref|NP_446375.1| phosphatidylinositol 3-kinase, C2 d... 47 0.010
gi|27807043|ref|NP_777002.1| phosphatidylinositol 4-kinase, cata... 47 0.010
gi|2136690|pir||S65741 1-phosphatidylinositol 4-kinase (EC 2.7.1... 47 0.010
gi|7547268|gb|AAB36289.2| type 3 phosphatidylinositol 4-kinase [... 47 0.010
gi|47226674|emb|CAG07833.1| unnamed protein product [Tetraodon n... 47 0.010
gi|48374081|ref|NP_955377.2| similar to phosphatidylinositol 4-k... 46 0.013
gi|17554994|ref|NP_497853.1| splicing factor (147.3 kD) (3F354) ... 46 0.013
gi|50782499|ref|XP_423394.1| PREDICTED: similar to PIK4CB protei... 46 0.013
gi|47211517|emb|CAF90313.1| unnamed protein product [Tetraodon n... 46 0.017
gi|32398759|emb|CAD98719.1| phosphatidylinositol 3-kinase, root ... 45 0.023
gi|1709527|sp|P54675|P3K3_DICDI Phosphatidylinositol 3-kinase 3 ... 45 0.023
gi|38090007|ref|XP_356175.1| similar to ataxia telangiectasia an... 45 0.023
gi|39586587|emb|CAE73714.1| Hypothetical protein CBG21228 [Caeno... 45 0.023
gi|26346703|dbj|BAC37000.1| unnamed protein product [Mus musculus] 45 0.023
gi|30048086|gb|AAH51246.1| Pik3cg protein [Mus musculus] 45 0.023
gi|9937984|ref|NP_064668.1| phosphoinositide-3-kinase, catalytic... 45 0.023
gi|47228503|emb|CAG05323.1| unnamed protein product [Tetraodon n... 45 0.023
gi|11890408|gb|AAG41122.1| phosphatidylinositol 3-kinase gamma i... 45 0.023
gi|28829799|gb|AAO52301.1| similar to Dictyostelium discoideum (... 45 0.029
gi|6324062|ref|NP_014132.1| catalyzes first step in the biosynth... 45 0.029
gi|32197216|gb|AAH53654.1| PIK4CA protein [Homo sapiens] 45 0.029
gi|46122243|ref|XP_385675.1| hypothetical protein FG05499.1 [Gib... 45 0.038
gi|1709526|sp|P54674|P3K2_DICDI Phosphatidylinositol 3-kinase 2 ... 45 0.038
gi|19074668|ref|NP_586174.1| PHOSPHATIDYL INOSITOL-3-KINASE (C-T... 45 0.038
gi|46362436|gb|AAH68983.1| Zgc:77033 protein [Danio rerio] 44 0.050
gi|38110640|gb|EAA56328.1| hypothetical protein MG06299.4 [Magna... 44 0.050
gi|34783827|gb|AAH57425.1| LOC407647 protein [Danio rerio] 44 0.050
gi|39597228|emb|CAE59456.1| Hypothetical protein CBG02835 [Caeno... 44 0.065
gi|50760287|ref|XP_417956.1| PREDICTED: similar to phosphoinosit... 44 0.065
gi|47215828|emb|CAF96791.1| unnamed protein product [Tetraodon n... 44 0.065
gi|47206366|emb|CAF94954.1| unnamed protein product [Tetraodon n... 44 0.086
gi|29246528|gb|EAA38121.1| GLP_44_18876_25655 [Giardia lamblia A... 44 0.086
gi|46431887|gb|EAK91408.1| hypothetical protein CaO19.8871 [Cand... 44 0.086
gi|7434347|pir||PC4347 phosphoinositide 3-kinase (EC 2.7.-.-) T1... 44 0.086
gi|14245711|dbj|BAB56149.1| phosphatidylinositol 4-kinase like p... 44 0.086
gi|38073314|ref|XP_283638.2| similar to Phosphatidylinositol-4-p... 43 0.15
gi|46810282|ref|NP_997566.1| phosphatidylinositol 3-kinase, C2 d... 43 0.15
gi|7434349|pir||JC5985 phosphoinositide 3-kinase C2gamma - mouse 43 0.15
gi|34880210|ref|XP_213879.2| similar to phosphoinositide-3-kinas... 43 0.15
gi|6755060|ref|NP_035214.1| phosphatidylinositol 3-kinase, C2 do... 43 0.15
gi|3954946|emb|CAA74194.1| PI-3 kinase [Homo sapiens] 42 0.25
gi|50419275|ref|XP_458161.1| unnamed protein product [Debaryomyc... 42 0.25
gi|13632400|sp|O00750|PK3B_HUMAN Phosphatidylinositol-4-phosphat... 42 0.25
gi|15451926|ref|NP_002637.2| phosphoinositide-3-kinase, class 2,... 42 0.25
gi|50729062|ref|XP_416412.1| PREDICTED: similar to Phosphatidyli... 42 0.25
gi|7434346|pir||PC4346 phosphoinositide 3-kinase (EC 2.7.-.-) T1... 42 0.32
gi|50303691|ref|XP_451788.1| unnamed protein product [Kluyveromy... 41 0.42
gi|12329946|emb|CAC24651.1| probable phosphatidylinositol 3-kina... 41 0.55
gi|47213438|emb|CAF89545.1| unnamed protein product [Tetraodon n... 41 0.55
gi|26342569|dbj|BAC34941.1| unnamed protein product [Mus musculus] 41 0.55
gi|23128530|ref|ZP_00110375.1| COG0784: FOG: CheY-like receiver ... 40 0.72
gi|47216078|emb|CAG04817.1| unnamed protein product [Tetraodon n... 40 0.72
gi|1709525|sp|P54673|P3K1_DICDI Phosphatidylinositol 3-kinase 1 ... 40 0.95
gi|47223252|emb|CAF98636.1| unnamed protein product [Tetraodon n... 40 0.95
gi|37589499|gb|AAH59895.1| Unknown (protein for MGC:69841) [Mus ... 40 1.2
gi|23613470|ref|NP_703314.1| UMP-CMP kinase, putative [Plasmodiu... 40 1.2
gi|15223328|ref|NP_173994.1| expressed protein [Arabidopsis thal... 39 1.6
gi|48097463|ref|XP_391900.1| similar to CG8939-PA [Apis mellifera] 39 1.6
gi|31126794|gb|AAP44713.1| hypothetical protein [Oryza sativa (j... 39 1.6
gi|46135877|ref|XP_389630.1| conserved hypothetical protein [Gib... 39 1.6
gi|23486884|gb|EAA20916.1| karyopherin beta [Plasmodium yoelii y... 39 2.1
gi|20177117|gb|AAM12261.1| RE37107p [Drosophila melanogaster] 39 2.1
gi|24665422|ref|NP_730184.1| CG32164-PA [Drosophila melanogaster... 39 2.1
gi|50556624|ref|XP_505720.1| hypothetical protein [Yarrowia lipo... 39 2.1
gi|24665414|ref|NP_730182.1| CG32165-PA [Drosophila melanogaster... 39 2.1
gi|23488560|gb|EAA21348.1| hypothetical protein [Plasmodium yoel... 39 2.8
gi|19115264|ref|NP_594352.1| putative dna repair/transcription p... 39 2.8
gi|23613261|ref|NP_703583.1| karyopherin beta [Plasmodium falcip... 39 2.8
gi|47224471|emb|CAG08721.1| unnamed protein product [Tetraodon n... 39 2.8
gi|49387757|dbj|BAD26245.1| putative TIP120 protein [Oryza sativ... 38 3.6
gi|15223705|ref|NP_175516.1| phosphatidylinositol 4-kinase, puta... 38 3.6
gi|19173068|ref|NP_597619.1| PHOSPHATIDYLINOSITOL-4-KINASE CATAL... 38 3.6
gi|3789970|gb|AAC67566.1| fibrinogen A-alpha chain [Macropus rufus] 38 3.6
gi|2502028|gb|AAC50033.1| unknown [Aspergillus fumigatus] 38 4.7
gi|22536967|ref|NP_687818.1| major facilitator family protein [S... 37 6.1
gi|25010877|ref|NP_735272.1| Unknown [Streptococcus agalactiae N... 37 6.1
gi|46435252|gb|EAK94638.1| hypothetical protein CaO19.11165 [Can... 37 6.1
gi|25405292|pir||F96529 probable Phosphatidylinositol 4-kinase P... 37 6.1
gi|25453506|pir||T52022 1-phosphatidylinositol 4-kinase (EC 2.7.... 37 6.1
gi|22330126|ref|NP_175359.2| phosphatidylinositol 3- and 4-kinas... 37 6.1
gi|49093170|ref|XP_408046.1| hypothetical protein AN3909.2 [Aspe... 37 6.1
gi|23484649|gb|EAA19907.1| hypothetical protein [Plasmodium yoel... 37 8.0
gi|4504951|ref|NP_002282.1| laminin, beta 1 precursor [Homo sapi... 37 8.0
gi|38197240|gb|AAH26018.2| LAMB1 protein [Homo sapiens] 37 8.0
>gi|41018240|sp|Q95Q95|TOR_CAEEL Target of rapamycin homolog (CeTOR)
(Lethal protein 363)
gi|7494793|pir||T25444 hypothetical protein B0261.2 - Caenorhabditis
elegans
Length = 2697
Score = 5109 bits (13252), Expect = 0.0
Identities = 2597/2697 (96%), Positives = 2597/2697 (96%)
Frame = +1
Query: 1 MLQQHGISFQMNADRQNKAATTSNRIVSAPATNEFDERHRKQGIDAARALASQYRSRITE 180
MLQQHGISFQMNADRQNKAATTSNRIVSAPATNEFDERHRKQGIDAARALASQYRSRITE
Sbjct: 1 MLQQHGISFQMNADRQNKAATTSNRIVSAPATNEFDERHRKQGIDAARALASQYRSRITE 60
Query: 181 NRDANQRQAARELSRYVRSELKDEPNTFSDAFLNAIDGRTDIASQSAIYNCMKSNSNIDQ 360
NRDANQRQAARELSRYVRSELKDEPNTFSDAFLNAIDGRTDIASQSAIYNCMKSNSNIDQ
Sbjct: 61 NRDANQRQAARELSRYVRSELKDEPNTFSDAFLNAIDGRTDIASQSAIYNCMKSNSNIDQ 120
Query: 361 KRAGIYLIVCLAETHSGNVIRYANYLLKMLNNGNGLDEDTVKMASKALAFLIATCKSYAA 540
KRAGIYLIVCLAETHSGNVIRYANYLLKMLNNGNGLDEDTVKMASKALAFLIATCKSYAA
Sbjct: 121 KRAGIYLIVCLAETHSGNVIRYANYLLKMLNNGNGLDEDTVKMASKALAFLIATCKSYAA 180
Query: 541 ELVDRCLDHCHEWLGQNVPHSQQPKNQQEIDQIRRLAASHLSRELALATPTAFFLRVNLF 720
ELVDRCLDHCHEWLGQNVPHSQQPKNQQEIDQIRRLAASHLSRELALATPTAFFLRVNLF
Sbjct: 181 ELVDRCLDHCHEWLGQNVPHSQQPKNQQEIDQIRRLAASHLSRELALATPTAFFLRVNLF 240
Query: 721 FKYIFNAVRDKNPAVRIAGIDALHVVLTIVSQREAKNKTEWFKKCFDEALEGQPNPSQKD 900
FKYIFNAVRDKNPAVRIAGIDALHVVLTIVSQREAKNKTEWFKKCFDEALEGQPNPSQKD
Sbjct: 241 FKYIFNAVRDKNPAVRIAGIDALHVVLTIVSQREAKNKTEWFKKCFDEALEGQPNPSQKD 300
Query: 901 DLDRWHAVALILNELLRISDQRFELIRCESSQFIKQKFLKEDEEEGVEWLVLTKQQTIVE 1080
DLDRWHAVALILNELLRISDQRFELIRCESSQFIKQKFLKEDEEEGVEWLVLTKQQTIVE
Sbjct: 301 DLDRWHAVALILNELLRISDQRFELIRCESSQFIKQKFLKEDEEEGVEWLVLTKQQTIVE 360
Query: 1081 SVTARKLVLERFPKILDCVRQIIPLANKTSSTKQQSSIYLNTVLMQLLPRICAFPQCDRT 1260
SVTARKLVLERFPKILDCVRQIIPLANKTSSTKQQSSIYLNTVLMQLLPRICAFPQCDRT
Sbjct: 361 SVTARKLVLERFPKILDCVRQIIPLANKTSSTKQQSSIYLNTVLMQLLPRICAFPQCDRT 420
Query: 1261 FQTISFDTSFTILQRNAVAAPAIGMMMLSNPDVHATHIEKTISFISAAIKKTTNSDVLDN 1440
FQTISFDTSFTILQRNAVAAPAIGMMMLSNPDVHATHIEKTISFISAAIKKTTNSDVLDN
Sbjct: 421 FQTISFDTSFTILQRNAVAAPAIGMMMLSNPDVHATHIEKTISFISAAIKKTTNSDVLDN 480
Query: 1441 YFTFLFLFVDAYHEQVTTQIKAIIPQLMDITLSRSLANVLKMIMMRIPKLRLNVQDGVMA 1620
YFTFLFLFVDAYHEQVTTQIKAIIPQLMDITLSRSLANVLKMIMMRIPKLRLNVQDGVMA
Sbjct: 481 YFTFLFLFVDAYHEQVTTQIKAIIPQLMDITLSRSLANVLKMIMMRIPKLRLNVQDGVMA 540
Query: 1621 SVYQTLTGSLIPPKSEPIGRPASPKAILQKAETDPKELQRIVLAVDVLGEFYFSRGALQR 1800
SVYQTLTGSLIPPKSEPIGRPASPKAILQKAETDPKELQRIVLAVDVLGEFYFSRGALQR
Sbjct: 541 SVYQTLTGSLIPPKSEPIGRPASPKAILQKAETDPKELQRIVLAVDVLGEFYFSRGALQR 600
Query: 1801 IMQYVADYYLTADNVEIRLAAVSSCCEMVVPFVGVYKKVTSDKRNSLLQTIYGVLRAVCS 1980
IMQYVADYYLTADNVEIRLAAVSSCCEMVVPFVGVYKKVTSDKRNSLLQTIYGVLRAVCS
Sbjct: 601 IMQYVADYYLTADNVEIRLAAVSSCCEMVVPFVGVYKKVTSDKRNSLLQTIYGVLRAVCS 660
Query: 1981 VIVNDQDVRVRMQVISCFGQMPRPFLAHLAQPEMLEVQFMALHDEKLEMQQACVTLLGRL 2160
VIVNDQDVRVRMQVISCFGQMPRPFLAHLAQPEMLEVQFMALHDEKLEMQQACVTLLGRL
Sbjct: 661 VIVNDQDVRVRMQVISCFGQMPRPFLAHLAQPEMLEVQFMALHDEKLEMQQACVTLLGRL 720
Query: 2161 AELNPAXXXXXXXXXXXXXXSQMQQSGQARLEQHSAKMIAQLAKQSPKFMRPYVGSLMIA 2340
AELNPA SQMQQSGQARLEQHSAKMIAQLAKQSPKFMRPYVGSLMIA
Sbjct: 721 AELNPALVLPRLRLMLLETLSQMQQSGQARLEQHSAKMIAQLAKQSPKFMRPYVGSLMIA 780
Query: 2341 MIPKLRNDQKYAEVTAQVLNAVSEIAVIGGAEIVKNLKPLFEKLTHMINDSSSLHKREAA 2520
MIPKLRNDQKYAEVTAQVLNAVSEIAVIGGAEIVKNLKPLFEKLTHMINDSSSLHKREAA
Sbjct: 781 MIPKLRNDQKYAEVTAQVLNAVSEIAVIGGAEIVKNLKPLFEKLTHMINDSSSLHKREAA 840
Query: 2521 LRAIGGICRSTAYVVDPYRDYPSLLDDLLRILKTVMSNTMRREAIKTLGILGAIDPYTHK 2700
LRAIGGICRSTAYVVDPYRDYPSLLDDLLRILKTVMSNTMRREAIKTLGILGAIDPYTHK
Sbjct: 841 LRAIGGICRSTAYVVDPYRDYPSLLDDLLRILKTVMSNTMRREAIKTLGILGAIDPYTHK 900
Query: 2701 VFTGSVQSSTAISTALSLPISETDSKDPRQDIIHWFNYEKCTLEEFYPAITIANLMLMMQ 2880
VFTGSVQSSTAISTALSLPISETDSKDPRQDIIHWFNYEKCTLEEFYPAITIANLMLMMQ
Sbjct: 901 VFTGSVQSSTAISTALSLPISETDSKDPRQDIIHWFNYEKCTLEEFYPAITIANLMLMMQ 960
Query: 2881 DEDSQSYAEIAQAIVTIFRSLGDMAPLYTEQVIPRLIEVCRRATESSNRANLREFFLQQL 3060
DEDSQSYAEIAQAIVTIFRSLGDMAPLYTEQVIPRLIEVCRRATESSNRANLREFFLQQL
Sbjct: 961 DEDSQSYAEIAQAIVTIFRSLGDMAPLYTEQVIPRLIEVCRRATESSNRANLREFFLQQL 1020
Query: 3061 ANFVAIIRKHAAPYMPAIFTIIADAWKEDISVKMVVIEVLTDMGTAIGNDFSKYTGELIP 3240
ANFVAIIRKHAAPYMPAIFTIIADAWKEDISVKMVVIEVLTDMGTAIGNDFSKYTGELIP
Sbjct: 1021 ANFVAIIRKHAAPYMPAIFTIIADAWKEDISVKMVVIEVLTDMGTAIGNDFSKYTGELIP 1080
Query: 3241 YLLTVLQTDKTKERVLTVKVMESIQKLTHCIXXXXXXXXXXXXXXXXXFSLKLSIRNTAL 3420
YLLTVLQTDKTKERVLTVKVMESIQKLTHCI FSLKLSIRNTAL
Sbjct: 1081 YLLTVLQTDKTKERVLTVKVMESIQKLTHCIVQHLHLVLPPLLIILDDFSLKLSIRNTAL 1140
Query: 3421 STVLHMTQQVDVSAYAPRMMQSWHHNISTAEMRDXXXXXXXXXXXXXXXFFDIFKRGVDQ 3600
STVLHMTQQVDVSAYAPRMMQSWHHNISTAEMRD FFDIFKRGVDQ
Sbjct: 1141 STVLHMTQQVDVSAYAPRMMQSWHHNISTAEMRDKLLLLLIEIIKQLGKFFDIFKRGVDQ 1200
Query: 3601 KLRDYNLDKSVHYEQYRKLAQRAQMSRDVLTSSVFAGSNGNIQYSSTQAGMRGQANNVYA 3780
KLRDYNLDKSVHYEQYRKLAQRAQMSRDVLTSSVFAGSNGNIQYSSTQAGMRGQANNVYA
Sbjct: 1201 KLRDYNLDKSVHYEQYRKLAQRAQMSRDVLTSSVFAGSNGNIQYSSTQAGMRGQANNVYA 1260
Query: 3781 NNDLHERLMNGSIDSGASRQDNRDDYYRYGVEEKKEVPKVAPTTARPTSELVTVQITKQR 3960
NNDLHERLMNGSIDSGASRQDNRDDYYRYGVEEKKEVPKVAPTTARPTSELVTVQITKQR
Sbjct: 1261 NNDLHERLMNGSIDSGASRQDNRDDYYRYGVEEKKEVPKVAPTTARPTSELVTVQITKQR 1320
Query: 3961 LNKDALMPQWKNENLTSKDEWLQWLMKIRIGFLTYGSSPSLRAASSLGDQHPHLARDLFP 4140
LNKDALMPQWKNENLTSKDEWLQWLMKIRIGFLTYGSSPSLRAASSLGDQHPHLARDLFP
Sbjct: 1321 LNKDALMPQWKNENLTSKDEWLQWLMKIRIGFLTYGSSPSLRAASSLGDQHPHLARDLFP 1380
Query: 4141 AAFMSVWTELDSDVQNDLTSCLLRAISTGIPELIQTILNLAEFMDHSEKGPLPISHDVLG 4320
AAFMSVWTELDSDVQNDLTSCLLRAISTGIPELIQTILNLAEFMDHSEKGPLPISHDVLG
Sbjct: 1381 AAFMSVWTELDSDVQNDLTSCLLRAISTGIPELIQTILNLAEFMDHSEKGPLPISHDVLG 1440
Query: 4321 RWAEQTKAFAKACRYKEMSVLKKSGSMQTTFTRKVKLEPNDCQSLITYANKLNVQEEAAG 4500
RWAEQTKAFAKACRYKEMSVLKKSGSMQTTFTRKVKLEPNDCQSLITYANKLNVQEEAAG
Sbjct: 1441 RWAEQTKAFAKACRYKEMSVLKKSGSMQTTFTRKVKLEPNDCQSLITYANKLNVQEEAAG 1500
Query: 4501 VVRYAERNEMNFQMRGRWYEKLNEWEKALGAYELEEKKKSSCPNLQVYDEKDHLMTPXXX 4680
VVRYAERNEMNFQMRGRWYEKLNEWEKALGAYELEEKKKSSCPNLQVYDEKDHLMTP
Sbjct: 1501 VVRYAERNEMNFQMRGRWYEKLNEWEKALGAYELEEKKKSSCPNLQVYDEKDHLMTPEEA 1560
Query: 4681 XXXXXXRMHEMRCLEALGRWDELNSKSVVWADQRGNRNDSVRDEINKKQLDHKMAVIAAR 4860
RMHEMRCLEALGRWDELNSKSVVWADQRGNRNDSVRDEINKKQLDHKMAVIAAR
Sbjct: 1561 ATAEEARMHEMRCLEALGRWDELNSKSVVWADQRGNRNDSVRDEINKKQLDHKMAVIAAR 1620
Query: 4861 GAWAVDNWERMADYVSVISENTQDGAMLRAVVAVHNDENTKAMGLIEKVREMIDSELTAM 5040
GAWAVDNWERMADYVSVISENTQDGAMLRAVVAVHNDENTKAMGLIEKVREMIDSELTAM
Sbjct: 1621 GAWAVDNWERMADYVSVISENTQDGAMLRAVVAVHNDENTKAMGLIEKVREMIDSELTAM 1680
Query: 5041 ANESYERAYIPMVSVQQMAELEEAIEYKTRPERRPRIALLWSRRLQGCRRNVEQWQRLIM 5220
ANESYERAYIPMVSVQQMAELEEAIEYKTRPERRPRIALLWSRRLQGCRRNVEQWQRLIM
Sbjct: 1681 ANESYERAYIPMVSVQQMAELEEAIEYKTRPERRPRIALLWSRRLQGCRRNVEQWQRLIM 1740
Query: 5221 LRGLVLSPQEMHPLRVKFSSMCRKQGKNSMSRAVLRELLSLPANSDLVRAKAPFDKPLLV 5400
LRGLVLSPQEMHPLRVKFSSMCRKQGKNSMSRAVLRELLSLPANSDLVRAKAPFDKPLLV
Sbjct: 1741 LRGLVLSPQEMHPLRVKFSSMCRKQGKNSMSRAVLRELLSLPANSDLVRAKAPFDKPLLV 1800
Query: 5401 LALAKQLYQDDHKDEAIRALEDLANHWNKRINPIPKATGRELIPPSTKEPARICAKVLLK 5580
LALAKQLYQDDHKDEAIRALEDLANHWNKRINPIPKATGRELIPPSTKEPARICAKVLLK
Sbjct: 1801 LALAKQLYQDDHKDEAIRALEDLANHWNKRINPIPKATGRELIPPSTKEPARICAKVLLK 1860
Query: 5581 LGEWTELKSKTSNNMQVGELSFVRQQVSPQYRTKESRTPETIAFENTINYYQQATQYDPG 5760
LGEWTELKSKTSNNMQVGELSFVRQQVSPQYRTKESRTPETIAFENTINYYQQATQYDPG
Sbjct: 1861 LGEWTELKSKTSNNMQVGELSFVRQQVSPQYRTKESRTPETIAFENTINYYQQATQYDPG 1920
Query: 5761 WHKVWHKLASTHFYAVCRERPHPTTVISXXXXXXXXKKMHIXXXXXXXXXXXXXXXXXXX 5940
WHKVWHKLASTHFYAVCRERPHPTTVIS KKMHI
Sbjct: 1921 WHKVWHKLASTHFYAVCRERPHPTTVISPPQQPQQPKKMHIPPVTRATSPPPPAQKSPQP 1980
Query: 5941 XXFHSITEPLSVIIDYXXXXXXXXXXXXXXXXAYLSSNSSLPPQHHHVSPLSNDSPSNSA 6120
FHSITEPLSVIIDY AYLSSNSSLPPQHHHVSPLSNDSPSNSA
Sbjct: 1981 APFHSITEPLSVIIDYPVPPPLGSLVGLPPMPAYLSSNSSLPPQHHHVSPLSNDSPSNSA 2040
Query: 6121 ENKLYLKHAAHAVRCFAKALMCSPGSRLEDTLRLMQLWFDHGDDKDQDVYFALTETIFDL 6300
ENKLYLKHAAHAVRCFAKALMCSPGSRLEDTLRLMQLWFDHGDDKDQDVYFALTETIFDL
Sbjct: 2041 ENKLYLKHAAHAVRCFAKALMCSPGSRLEDTLRLMQLWFDHGDDKDQDVYFALTETIFDL 2100
Query: 6301 PVTTWLEAIPQLMARLDCPDDQKSVQLVLRVLCEIARHRPQAVIYALTVASRSKDVHRSK 6480
PVTTWLEAIPQLMARLDCPDDQKSVQLVLRVLCEIARHRPQAVIYALTVASRSKDVHRSK
Sbjct: 2101 PVTTWLEAIPQLMARLDCPDDQKSVQLVLRVLCEIARHRPQAVIYALTVASRSKDVHRSK 2160
Query: 6481 NAGTVLEKMMEYHSKLVREASLVTEELVRCAILWHEQWHDALDDASRVYFHRRLQDNNVQ 6660
NAGTVLEKMMEYHSKLVREASLVTEELVRCAILWHEQWHDALDDASRVYFHRRLQDNNVQ
Sbjct: 2161 NAGTVLEKMMEYHSKLVREASLVTEELVRCAILWHEQWHDALDDASRVYFHRRLQDNNVQ 2220
Query: 6661 AMFDALRNMNDLMQKGAPTTMKEHSFQQTYSSDLKEAGRYVQAFESSGNVKDLNQAWEIY 6840
AMFDALRNMNDLMQKGAPTTMKEHSFQQTYSSDLKEAGRYVQAFESSGNVKDLNQAWEIY
Sbjct: 2221 AMFDALRNMNDLMQKGAPTTMKEHSFQQTYSSDLKEAGRYVQAFESSGNVKDLNQAWEIY 2280
Query: 6841 CSVFKKLRDQLATLNSLDLVYVSPNLVSAKDLELVVPGTYDPSAPIVSIQSFSSKMNVIT 7020
CSVFKKLRDQLATLNSLDLVYVSPNLVSAKDLELVVPGTYDPSAPIVSIQSFSSKMNVIT
Sbjct: 2281 CSVFKKLRDQLATLNSLDLVYVSPNLVSAKDLELVVPGTYDPSAPIVSIQSFSSKMNVIT 2340
Query: 7021 SKQRPRKMVIRGSNGLDYQFLLKGHEDPRQDERVMQLFGLVNTLLANNSETCRRNLTIQR 7200
SKQRPRKMVIRGSNGLDYQFLLKGHEDPRQDERVMQLFGLVNTLLANNSETCRRNLTIQR
Sbjct: 2341 SKQRPRKMVIRGSNGLDYQFLLKGHEDPRQDERVMQLFGLVNTLLANNSETCRRNLTIQR 2400
Query: 7201 YSIVALSKDSGLIGWVPNCDTLHTLVKEYREKKAKIPLSIEHKTLQKLSLETEHLTLMQK 7380
YSIVALSKDSGLIGWVPNCDTLHTLVKEYREKKAKIPLSIEHKTLQKLSLETEHLTLMQK
Sbjct: 2401 YSIVALSKDSGLIGWVPNCDTLHTLVKEYREKKAKIPLSIEHKTLQKLSLETEHLTLMQK 2460
Query: 7381 LQLFESALSVTQGEDLRHVLWLKSPSSEVWFDRRTNYTRSVACMSMVGYILGLGDRHPSN 7560
LQLFESALSVTQGEDLRHVLWLKSPSSEVWFDRRTNYTRSVACMSMVGYILGLGDRHPSN
Sbjct: 2461 LQLFESALSVTQGEDLRHVLWLKSPSSEVWFDRRTNYTRSVACMSMVGYILGLGDRHPSN 2520
Query: 7561 LMLDRLTGKVVHIDFGDCFEVAMLREKFPERVPFRLTRMLINAMEVTGLDGVYNYTAERV 7740
LMLDRLTGKVVHIDFGDCFEVAMLREKFPERVPFRLTRMLINAMEVTGLDGVYNYTAERV
Sbjct: 2521 LMLDRLTGKVVHIDFGDCFEVAMLREKFPERVPFRLTRMLINAMEVTGLDGVYNYTAERV 2580
Query: 7741 LKMLRTNQESLLAVLEAFVYDPVINWRLVEGMKKDPKTRKDTGGRQNMAGAVLPSSSTTD 7920
LKMLRTNQESLLAVLEAFVYDPVINWRLVEGMKKDPKTRKDTGGRQNMAGAVLPSSSTTD
Sbjct: 2581 LKMLRTNQESLLAVLEAFVYDPVINWRLVEGMKKDPKTRKDTGGRQNMAGAVLPSSSTTD 2640
Query: 7921 SIMETIKRKLDGTEFVHTDGSTPPEPLQVTEQLAMLTEQATSPLNLCQSYIGWCPFW 8091
SIMETIKRKLDGTEFVHTDGSTPPEPLQVTEQLAMLTEQATSPLNLCQSYIGWCPFW
Sbjct: 2641 SIMETIKRKLDGTEFVHTDGSTPPEPLQVTEQLAMLTEQATSPLNLCQSYIGWCPFW 2697
>gi|32563905|ref|NP_491549.2| lethal protein 363 family member, LEThal
LET-363 (let-363) [Caenorhabditis elegans]
gi|26251687|gb|AAN84885.1| Lethal protein 363, isoform a
[Caenorhabditis elegans]
Length = 2695
Score = 5089 bits (13201), Expect = 0.0
Identities = 2592/2699 (96%), Positives = 2593/2699 (96%), Gaps = 2/2699 (0%)
Frame = +1
Query: 1 MLQQHGISFQMNADRQNKAATTSNRIVSAPATNEFDERHRKQGIDAARALASQYRSRITE 180
MLQQHGISFQMNADRQNKAATTSNRIVSAPATNEFDERHRKQGIDAARALASQYRSRITE
Sbjct: 1 MLQQHGISFQMNADRQNKAATTSNRIVSAPATNEFDERHRKQGIDAARALASQYRSRITE 60
Query: 181 NRDANQRQAARELSRYVRSELKDEPNTFSDAFLNAIDGRTDIASQSAIYNCMKSNSNIDQ 360
NRDANQRQAARELSRYVRSELKDEPNTFSDAFLNAIDGRTDIASQSAIYNCMKSNSNIDQ
Sbjct: 61 NRDANQRQAARELSRYVRSELKDEPNTFSDAFLNAIDGRTDIASQSAIYNCMKSNSNIDQ 120
Query: 361 KRAGIYLIVCLAETHSGNVIRYANYLLKMLNNGNGLDEDTVKMASKALAFLIATCKSYAA 540
KRAGIYLIVCLAETHSGNVIRYANYLLKMLNNGNGLDEDTVKMASKALAFLIATCKSYAA
Sbjct: 121 KRAGIYLIVCLAETHSGNVIRYANYLLKMLNNGNGLDEDTVKMASKALAFLIATCKSYAA 180
Query: 541 ELVDRCLDHCHEWLGQNVPHSQQPKNQQEIDQIRRLAASHLSRELALATPTAFFLRVNLF 720
ELVDRCLDHCHEWLGQNVPHSQQPKNQQEIDQIRRLAASHLSRELALATPTAFFLRVNLF
Sbjct: 181 ELVDRCLDHCHEWLGQNVPHSQQPKNQQEIDQIRRLAASHLSRELALATPTAFFLRVNLF 240
Query: 721 FKYIFNAVRDKNPAVRIAGIDALHVVLTIVSQREAKNKTEWFKKCFDEALEGQPNPSQKD 900
FKYIFNAVRDKNPAVRIAGIDALHVVLTIVSQREAKNKTEWFKKCFDEALEGQPNPSQKD
Sbjct: 241 FKYIFNAVRDKNPAVRIAGIDALHVVLTIVSQREAKNKTEWFKKCFDEALEGQPNPSQKD 300
Query: 901 DLDRWHAVALILNELLRISDQRFELIRCESSQFIKQKFLKEDEEEGVEWLVLTKQQTIVE 1080
DLDRWHAVALILNELLRISDQRFELIRCESSQFIKQKFLKEDEEEGVEWLVLTKQQTIVE
Sbjct: 301 DLDRWHAVALILNELLRISDQRFELIRCESSQFIKQKFLKEDEEEGVEWLVLTKQQTIVE 360
Query: 1081 SVTARKLVLERFPKILDCVRQIIPLANKTSSTKQQSSIYLNTVLMQLLPRICAFPQCDRT 1260
SVTARKLVLERFPKILDCVRQIIPLANKTSSTKQQSSIYLNTVLMQLLPRICAFPQCDRT
Sbjct: 361 SVTARKLVLERFPKILDCVRQIIPLANKTSSTKQQSSIYLNTVLMQLLPRICAFPQCDRT 420
Query: 1261 FQTISFDTSFTILQRNAVAAPAIGMMMLSNPDVHATHIEKTISFISAAIKKTTNSDVLDN 1440
FQTISFDTSFTILQRNAVAAPAIGMMMLSNPDVHATHIEKTISFISAAIKKTTNSDVLDN
Sbjct: 421 FQTISFDTSFTILQRNAVAAPAIGMMMLSNPDVHATHIEKTISFISAAIKKTTNSDVLDN 480
Query: 1441 YFTFLFLFVDAYHEQVTTQIKAIIPQLMDITLSRSLANVLKMIMMRIPKLRLNVQDGVMA 1620
YFTFLFLFVDAYHEQVTTQIKAIIPQLMDITLSRSLANVLKMIMMRIPKLRLNVQDGVMA
Sbjct: 481 YFTFLFLFVDAYHEQVTTQIKAIIPQLMDITLSRSLANVLKMIMMRIPKLRLNVQDGVMA 540
Query: 1621 SVYQTLTGSLIPPKSEPIGRPASPKAILQKAETDPKELQRIVLAVDVLGEFYFSRGALQR 1800
SVYQTLTGSLIPPKSEPIGRPASPKAILQKAETDPKELQRIVLAVDVLGEFYFSRGALQR
Sbjct: 541 SVYQTLTGSLIPPKSEPIGRPASPKAILQKAETDPKELQRIVLAVDVLGEFYFSRGALQR 600
Query: 1801 IMQYVADYYLTADNVEIRLAAVSSCCEMVVPFVGVYKKVTSDKRNSLLQTIYGVLRAVCS 1980
IMQYVADYYLTADNVEIRLAAVSSCCEMVVPFVGVYKKVTSDKRNSLLQTIYGVLRAVCS
Sbjct: 601 IMQYVADYYLTADNVEIRLAAVSSCCEMVVPFVGVYKKVTSDKRNSLLQTIYGVLRAVCS 660
Query: 1981 VIVNDQDVRVRMQVISCFGQMPRPFLAHLAQPEMLEVQFMALHDEKLEMQQACVTLLGRL 2160
VIVNDQDVRVRMQVISCFGQMPRPFLAHLAQPEMLEVQFMALHDEKLEMQQACVTLLGRL
Sbjct: 661 VIVNDQDVRVRMQVISCFGQMPRPFLAHLAQPEMLEVQFMALHDEKLEMQQACVTLLGRL 720
Query: 2161 AELNPAXXXXXXXXXXXXXXSQMQQSGQARLEQHSAKMIAQLAKQSPKFMRPYVGSLMIA 2340
AELNPA SQMQQSGQARLEQHSAKMIAQLAKQSPKFMRPYVGSLMIA
Sbjct: 721 AELNPALVLPRLRLMLLETLSQMQQSGQARLEQHSAKMIAQLAKQSPKFMRPYVGSLMIA 780
Query: 2341 MIPKLRNDQKYAEVTAQVLNAVSEIAVIGGAEIVKNLKPLFEKLTHMINDSSSLHKREAA 2520
MIPKLRNDQKYAEVTAQVLNAVSEIAVIGGAEIVKNLKPLFEKLTHMINDSSSLHKREAA
Sbjct: 781 MIPKLRNDQKYAEVTAQVLNAVSEIAVIGGAEIVKNLKPLFEKLTHMINDSSSLHKREAA 840
Query: 2521 LRAIGGICRSTAYVVDPYRDYPSLLDDLLRILKTVMSNTMRREAIKTLGILGAIDPYTHK 2700
LRAIGGICRSTAYVVDPYRDYPSLLDDLLRILKTVMSNTMRREAIKTLGILGAIDPYTHK
Sbjct: 841 LRAIGGICRSTAYVVDPYRDYPSLLDDLLRILKTVMSNTMRREAIKTLGILGAIDPYTHK 900
Query: 2701 VFTGSVQSSTAISTALSLPISETDSKDPRQDIIHWFNYEKCTLEEFYPAITIANLMLMMQ 2880
VFTGSVQSSTAISTALSLPISETDSKDPRQDIIHWFNYEKCTLEEFYPAITIANLMLMMQ
Sbjct: 901 VFTGSVQSSTAISTALSLPISETDSKDPRQDIIHWFNYEKCTLEEFYPAITIANLMLMMQ 960
Query: 2881 DEDSQSYAEIAQAIVTIFRSLGDMAPLYTEQVIPRLIEVCRRATESSNRANLREFFLQQL 3060
DEDSQSYAEIAQAIVTIFRSLGDMAPLYTEQVIPRLIEVCRRATESSNRANLREFFLQQL
Sbjct: 961 DEDSQSYAEIAQAIVTIFRSLGDMAPLYTEQVIPRLIEVCRRATESSNRANLREFFLQQL 1020
Query: 3061 ANFVAIIRKHAAPYMPAIFTIIADAWKEDISVKMVVIEVLTDMGTAIGNDFSKYTGELIP 3240
ANFVAIIRKHAAPYMPAIFTIIADAWKEDISVKMVVIEVLTDMGTAIGNDFSKYTGELIP
Sbjct: 1021 ANFVAIIRKHAAPYMPAIFTIIADAWKEDISVKMVVIEVLTDMGTAIGNDFSKYTGELIP 1080
Query: 3241 YLLTVLQTDKTKERVLTVKVMESIQKLTHCIXXXXXXXXXXXXXXXXXFSLKLSIRNTAL 3420
YLLTVLQTDKTKERVLTVKVMESIQKLTHCI FSLKLSIRNTAL
Sbjct: 1081 YLLTVLQTDKTKERVLTVKVMESIQKLTHCIVQHLHLVLPPLLIILDDFSLKLSIRNTAL 1140
Query: 3421 STVLHMTQQVDVSAYAPRMMQSWHHNISTAEMRDXXXXXXXXXXXXXXXFFDIFKRGVDQ 3600
STVLHMTQQVDVSAYAPRMMQSWHHNISTAEMRD FFDIFKRGVDQ
Sbjct: 1141 STVLHMTQQVDVSAYAPRMMQSWHHNISTAEMRDKLLLLLIEIIKQLGKFFDIFKRGVDQ 1200
Query: 3601 KLRDYNLDKSVHYEQYRKLAQRAQMSRDVLTSSVFAGSNGNIQYSSTQAGMRGQANNVYA 3780
KLRDYNLDKSVHYEQYRKLAQRAQMSRDVLTSSVFAGSNGNIQYSSTQAGMRGQANNVYA
Sbjct: 1201 KLRDYNLDKSVHYEQYRKLAQRAQMSRDVLTSSVFAGSNGNIQYSSTQAGMRGQANNVYA 1260
Query: 3781 NNDLHERLMNGSIDSGASRQDNRDDYYRYGVEEK--KEVPKVAPTTARPTSELVTVQITK 3954
NNDLHERLMNGSIDSGASRQDNRDDYYRYGVEEK +EVPKVAPTTARPTSELVTVQITK
Sbjct: 1261 NNDLHERLMNGSIDSGASRQDNRDDYYRYGVEEKISEEVPKVAPTTARPTSELVTVQITK 1320
Query: 3955 QRLNKDALMPQWKNENLTSKDEWLQWLMKIRIGFLTYGSSPSLRAASSLGDQHPHLARDL 4134
QRLNKDALMPQWKNENLTSKDEWLQWLMKIRIGFLTYGSSPSLRAASSLGDQHPHLARDL
Sbjct: 1321 QRLNKDALMPQWKNENLTSKDEWLQWLMKIRIGFLTYGSSPSLRAASSLGDQHPHLARDL 1380
Query: 4135 FPAAFMSVWTELDSDVQNDLTSCLLRAISTGIPELIQTILNLAEFMDHSEKGPLPISHDV 4314
FPAAFMSVWTELDSDVQNDLTSCLLRAISTGIPELIQTILNLAEFMDHSEKGPLPISHDV
Sbjct: 1381 FPAAFMSVWTELDSDVQNDLTSCLLRAISTGIPELIQTILNLAEFMDHSEKGPLPISHDV 1440
Query: 4315 LGRWAEQTKAFAKACRYKEMSVLKKSGSMQTTFTRKVKLEPNDCQSLITYANKLNVQEEA 4494
LGRWAEQTKAFAKACRYKEMSVLKKSGSMQTTFTRKVKLEPNDCQSLITYANKLNVQEEA
Sbjct: 1441 LGRWAEQTKAFAKACRYKEMSVLKKSGSMQTTFTRKVKLEPNDCQSLITYANKLNVQEEA 1500
Query: 4495 AGVVRYAERNEMNFQMRGRWYEKLNEWEKALGAYELEEKKKSSCPNLQVYDEKDHLMTPX 4674
AGVVRYAERNEMNFQMRGRWYEKLNEWEKALGAYELEEKKKSSCPNLQVYDEKDHLMTP
Sbjct: 1501 AGVVRYAERNEMNFQMRGRWYEKLNEWEKALGAYELEEKKKSSCPNLQVYDEKDHLMTPE 1560
Query: 4675 XXXXXXXXRMHEMRCLEALGRWDELNSKSVVWADQRGNRNDSVRDEINKKQLDHKMAVIA 4854
RMHEMRCLEALGRWDELNSKSVVWADQRGNRNDSVRDEINKKQLDHKMAVIA
Sbjct: 1561 EAATAEEARMHEMRCLEALGRWDELNSKSVVWADQRGNRNDSVRDEINKKQLDHKMAVIA 1620
Query: 4855 ARGAWAVDNWERMADYVSVISENTQDGAMLRAVVAVHNDENTKAMGLIEKVREMIDSELT 5034
ARGAWAVDNWERMADYVSVISENTQDGAMLRAVVAVHNDENTKAMGLIEKVREMIDSELT
Sbjct: 1621 ARGAWAVDNWERMADYVSVISENTQDGAMLRAVVAVHNDENTKAMGLIEKVREMIDSELT 1680
Query: 5035 AMANESYERAYIPMVSVQQMAELEEAIEYKTRPERRPRIALLWSRRLQGCRRNVEQWQRL 5214
AMANESYERAYIPMVSVQQMAELEEAIEYKTRPERRPRIALLWSRRLQGCRRNVEQWQRL
Sbjct: 1681 AMANESYERAYIPMVSVQQMAELEEAIEYKTRPERRPRIALLWSRRLQGCRRNVEQWQRL 1740
Query: 5215 IMLRGLVLSPQEMHPLRVKFSSMCRKQGKNSMSRAVLRELLSLPANSDLVRAKAPFDKPL 5394
IMLRGLVLSPQEMHPLRVKFSSMCRKQGKNSMSRAVLRELLSLPANSDLVRAKAPFDKPL
Sbjct: 1741 IMLRGLVLSPQEMHPLRVKFSSMCRKQGKNSMSRAVLRELLSLPANSDLVRAKAPFDKPL 1800
Query: 5395 LVLALAKQLYQDDHKDEAIRALEDLANHWNKRINPIPKATGRELIPPSTKEPARICAKVL 5574
LVLALAKQLYQDDHKDEAIRALEDLANHWNKRINPIPKATGRELIPPSTKEPARICAKVL
Sbjct: 1801 LVLALAKQLYQDDHKDEAIRALEDLANHWNKRINPIPKATGRELIPPSTKEPARICAKVL 1860
Query: 5575 LKLGEWTELKSKTSNNMQVGELSFVRQQVSPQYRTKESRTPETIAFENTINYYQQATQYD 5754
LKLGEWTELKSKTSNNMQVGELSFVRQQVSPQYRTKESRTPETIAFENTINYYQQATQYD
Sbjct: 1861 LKLGEWTELKSKTSNNMQVGELSFVRQQVSPQYRTKESRTPETIAFENTINYYQQATQYD 1920
Query: 5755 PGWHKVWHKLASTHFYAVCRERPHPTTVISXXXXXXXXKKMHIXXXXXXXXXXXXXXXXX 5934
PGWHKVWHKLASTHFYAVCRERPHPTTVIS KKMHI
Sbjct: 1921 PGWHKVWHKLASTHFYAVCRERPHPTTVISPPQQPQQPKKMHIPPVTRATSPPPPAQKSP 1980
Query: 5935 XXXXFHSITEPLSVIIDYXXXXXXXXXXXXXXXXAYLSSNSSLPPQHHHVSPLSNDSPSN 6114
FHSITEPLSVIIDY AYLSSNSSLPPQHHHVSPLSNDSPSN
Sbjct: 1981 QPAPFHSITEPLSVIIDYPVPPPLGSLVGLPPMPAYLSSNSSLPPQHHHVSPLSNDSPSN 2040
Query: 6115 SAENKLYLKHAAHAVRCFAKALMCSPGSRLEDTLRLMQLWFDHGDDKDQDVYFALTETIF 6294
SAENKLYLKHAAHAVRCFAKALMCSPGSRLEDTLRLMQLWFDHGDDKDQDVYFALTETIF
Sbjct: 2041 SAENKLYLKHAAHAVRCFAKALMCSPGSRLEDTLRLMQLWFDHGDDKDQDVYFALTETIF 2100
Query: 6295 DLPVTTWLEAIPQLMARLDCPDDQKSVQLVLRVLCEIARHRPQAVIYALTVASRSKDVHR 6474
DLPVTTWLEAIPQLMARLDCPDDQKSVQLVLRVLCEIARHRPQAVIYALTVASRSKDVHR
Sbjct: 2101 DLPVTTWLEAIPQLMARLDCPDDQKSVQLVLRVLCEIARHRPQAVIYALTVASRSKDVHR 2160
Query: 6475 SKNAGTVLEKMMEYHSKLVREASLVTEELVRCAILWHEQWHDALDDASRVYFHRRLQDNN 6654
SKNAGTVLEKMMEYHSKLVREASLVTEELVRCAILWHEQWHDALDDASRVYFH DNN
Sbjct: 2161 SKNAGTVLEKMMEYHSKLVREASLVTEELVRCAILWHEQWHDALDDASRVYFH----DNN 2216
Query: 6655 VQAMFDALRNMNDLMQKGAPTTMKEHSFQQTYSSDLKEAGRYVQAFESSGNVKDLNQAWE 6834
VQAMFDALRNMNDLMQKGAPTTMKEHSFQQTYSSDLKEAGRYVQAFESSGNVKDLNQAWE
Sbjct: 2217 VQAMFDALRNMNDLMQKGAPTTMKEHSFQQTYSSDLKEAGRYVQAFESSGNVKDLNQAWE 2276
Query: 6835 IYCSVFKKLRDQLATLNSLDLVYVSPNLVSAKDLELVVPGTYDPSAPIVSIQSFSSKMNV 7014
IYCSVFKKLRDQLATLNSLDLVYVSPNLVSAKDLELVVPGTYDPSAPIVSIQSFSSKMNV
Sbjct: 2277 IYCSVFKKLRDQLATLNSLDLVYVSPNLVSAKDLELVVPGTYDPSAPIVSIQSFSSKMNV 2336
Query: 7015 ITSKQRPRKMVIRGSNGLDYQFLLKGHEDPRQDERVMQLFGLVNTLLANNSETCRRNLTI 7194
ITSKQRPRKMVIRGSNGLDYQFLLKGHEDPRQDERVMQLFGLVNTLLANNSETCRRNLTI
Sbjct: 2337 ITSKQRPRKMVIRGSNGLDYQFLLKGHEDPRQDERVMQLFGLVNTLLANNSETCRRNLTI 2396
Query: 7195 QRYSIVALSKDSGLIGWVPNCDTLHTLVKEYREKKAKIPLSIEHKTLQKLSLETEHLTLM 7374
QRYSIVALSKDSGLIGWVPNCDTLHTLVKEYREKKAKIPLSIEHKTLQKLSLETEHLTLM
Sbjct: 2397 QRYSIVALSKDSGLIGWVPNCDTLHTLVKEYREKKAKIPLSIEHKTLQKLSLETEHLTLM 2456
Query: 7375 QKLQLFESALSVTQGEDLRHVLWLKSPSSEVWFDRRTNYTRSVACMSMVGYILGLGDRHP 7554
QKLQLFESALSVTQGEDLRHVLWLKSPSSEVWFDRRTNYTRSVACMSMVGYILGLGDRHP
Sbjct: 2457 QKLQLFESALSVTQGEDLRHVLWLKSPSSEVWFDRRTNYTRSVACMSMVGYILGLGDRHP 2516
Query: 7555 SNLMLDRLTGKVVHIDFGDCFEVAMLREKFPERVPFRLTRMLINAMEVTGLDGVYNYTAE 7734
SNLMLDRLTGKVVHIDFGDCFEVAMLREKFPERVPFRLTRMLINAMEVTGLDGVYNYTAE
Sbjct: 2517 SNLMLDRLTGKVVHIDFGDCFEVAMLREKFPERVPFRLTRMLINAMEVTGLDGVYNYTAE 2576
Query: 7735 RVLKMLRTNQESLLAVLEAFVYDPVINWRLVEGMKKDPKTRKDTGGRQNMAGAVLPSSST 7914
RVLKMLRTNQESLLAVLEAFVYDPVINWRLVEGMKKDPKTRKDTGGRQNMAGAVLPSSST
Sbjct: 2577 RVLKMLRTNQESLLAVLEAFVYDPVINWRLVEGMKKDPKTRKDTGGRQNMAGAVLPSSST 2636
Query: 7915 TDSIMETIKRKLDGTEFVHTDGSTPPEPLQVTEQLAMLTEQATSPLNLCQSYIGWCPFW 8091
TDSIMETIKRKLDGTEFVHTDGSTPPEPLQVTEQLAMLTEQATSPLNLCQSYIGWCPFW
Sbjct: 2637 TDSIMETIKRKLDGTEFVHTDGSTPPEPLQVTEQLAMLTEQATSPLNLCQSYIGWCPFW 2695
>gi|32563909|ref|NP_491552.2| lethal protein 363, LEThal LET-363
(305.8 kD) (let-363) [Caenorhabditis elegans]
gi|26251688|gb|AAN84886.1| Lethal protein 363, isoform b
[Caenorhabditis elegans]
Length = 2692
Score = 5079 bits (13175), Expect = 0.0
Identities = 2589/2699 (95%), Positives = 2590/2699 (95%), Gaps = 2/2699 (0%)
Frame = +1
Query: 1 MLQQHGISFQMNADRQNKAATTSNRIVSAPATNEFDERHRKQGIDAARALASQYRSRITE 180
MLQQHGISFQMNADRQNKAATTSNRIVSAPATNEFDERHRKQGIDAARALASQYRSRITE
Sbjct: 1 MLQQHGISFQMNADRQNKAATTSNRIVSAPATNEFDERHRKQGIDAARALASQYRSRITE 60
Query: 181 NRDANQRQAARELSRYVRSELKDEPNTFSDAFLNAIDGRTDIASQSAIYNCMKSNSNIDQ 360
NRDANQRQAARELSRYVRSELKDEPNTFSDAFLNAIDGRTDIASQSAIYNCMKSNSNIDQ
Sbjct: 61 NRDANQRQAARELSRYVRSELKDEPNTFSDAFLNAIDGRTDIASQSAIYNCMKSNSNIDQ 120
Query: 361 KRAGIYLIVCLAETHSGNVIRYANYLLKMLNNGNGLDEDTVKMASKALAFLIATCKSYAA 540
KRAGIYLIVCLAETHSGNVIRYANYLLKMLNNGNGLDEDTVKMASKALAFLIATCKSYAA
Sbjct: 121 KRAGIYLIVCLAETHSGNVIRYANYLLKMLNNGNGLDEDTVKMASKALAFLIATCKSYAA 180
Query: 541 ELVDRCLDHCHEWLGQNVPHSQQPKNQQEIDQIRRLAASHLSRELALATPTAFFLRVNLF 720
ELVDRCLDHCHEWLGQNVPHSQQPKNQQEIDQIRRLAASHLSRELALATPTAFFLRVNLF
Sbjct: 181 ELVDRCLDHCHEWLGQNVPHSQQPKNQQEIDQIRRLAASHLSRELALATPTAFFLRVNLF 240
Query: 721 FKYIFNAVRDKNPAVRIAGIDALHVVLTIVSQREAKNKTEWFKKCFDEALEGQPNPSQKD 900
FKYIFNAVRDKNPAVRIAGIDALHVVLTIVSQREAKNKTEWFKKCFDEALEGQPNPSQKD
Sbjct: 241 FKYIFNAVRDKNPAVRIAGIDALHVVLTIVSQREAKNKTEWFKKCFDEALEGQPNPSQKD 300
Query: 901 DLDRWHAVALILNELLRISDQRFELIRCESSQFIKQKFLKEDEEEGVEWLVLTKQQTIVE 1080
DLDRWHAVALILNELLRISDQRFELIRCESSQFIKQKFLKEDEEEGVEWLVLTKQQTIVE
Sbjct: 301 DLDRWHAVALILNELLRISDQRFELIRCESSQFIKQKFLKEDEEEGVEWLVLTKQQTIVE 360
Query: 1081 SVTARKLVLERFPKILDCVRQIIPLANKTSSTKQQSSIYLNTVLMQLLPRICAFPQCDRT 1260
SVTARKLVLERFPKILDCVRQIIPLANKTSSTKQQSSIYLNTVLMQLLPRICAFPQCDRT
Sbjct: 361 SVTARKLVLERFPKILDCVRQIIPLANKTSSTKQQSSIYLNTVLMQLLPRICAFPQCDRT 420
Query: 1261 FQTISFDTSFTILQRNAVAAPAIGMMMLSNPDVHATHIEKTISFISAAIKKTTNSDVLDN 1440
FQTISFDTSFTILQRNAVAAPAIGMMMLSNPDVHATHIEKTISFISAAIKKTTNSDVLDN
Sbjct: 421 FQTISFDTSFTILQRNAVAAPAIGMMMLSNPDVHATHIEKTISFISAAIKKTTNSDVLDN 480
Query: 1441 YFTFLFLFVDAYHEQVTTQIKAIIPQLMDITLSRSLANVLKMIMMRIPKLRLNVQDGVMA 1620
YFTFLFLFVDAYHEQVTTQIKAIIPQLMDITLSRSLANVLKMIMMRIPKLRLNVQDGVMA
Sbjct: 481 YFTFLFLFVDAYHEQVTTQIKAIIPQLMDITLSRSLANVLKMIMMRIPKLRLNVQDGVMA 540
Query: 1621 SVYQTLTGSLIPPKSEPIGRPASPKAILQKAETDPKELQRIVLAVDVLGEFYFSRGALQR 1800
SVYQTLTGSLIPPKSEPIGRPASPKAILQKAETDPKELQRIVLAVDVLGEFYFSRGALQR
Sbjct: 541 SVYQTLTGSLIPPKSEPIGRPASPKAILQKAETDPKELQRIVLAVDVLGEFYFSRGALQR 600
Query: 1801 IMQYVADYYLTADNVEIRLAAVSSCCEMVVPFVGVYKKVTSDKRNSLLQTIYGVLRAVCS 1980
IMQYVADYYLTADNVEIRLAAVSSCCEMVVPFVGVYKKVTSDKRNSLLQTIYGVLRAVCS
Sbjct: 601 IMQYVADYYLTADNVEIRLAAVSSCCEMVVPFVGVYKKVTSDKRNSLLQTIYGVLRAVCS 660
Query: 1981 VIVNDQDVRVRMQVISCFGQMPRPFLAHLAQPEMLEVQFMALHDEKLEMQQACVTLLGRL 2160
VIVNDQDVRVRMQVISCFGQMPRPFLAHLAQPEMLEVQFMALHDEKLEMQQACVTLLGRL
Sbjct: 661 VIVNDQDVRVRMQVISCFGQMPRPFLAHLAQPEMLEVQFMALHDEKLEMQQACVTLLGRL 720
Query: 2161 AELNPAXXXXXXXXXXXXXXSQMQQSGQARLEQHSAKMIAQLAKQSPKFMRPYVGSLMIA 2340
AELNPA SQMQQSGQARLEQHSAKMIAQLAKQSPKFMRPYVGSLMIA
Sbjct: 721 AELNPALVLPRLRLMLLETLSQMQQSGQARLEQHSAKMIAQLAKQSPKFMRPYVGSLMIA 780
Query: 2341 MIPKLRNDQKYAEVTAQVLNAVSEIAVIGGAEIVKNLKPLFEKLTHMINDSSSLHKREAA 2520
MIPKLRNDQKYAEVTAQVLNAVSEIAVIGGAEIVKNLKPLFEKLTHMINDSSSLHKREAA
Sbjct: 781 MIPKLRNDQKYAEVTAQVLNAVSEIAVIGGAEIVKNLKPLFEKLTHMINDSSSLHKREAA 840
Query: 2521 LRAIGGICRSTAYVVDPYRDYPSLLDDLLRILKTVMSNTMRREAIKTLGILGAIDPYTHK 2700
LRAIGGICRSTAYVVDPYRDYPSLLDDLLRILKTVMSNTMRREAIKTLGILGAIDPYTHK
Sbjct: 841 LRAIGGICRSTAYVVDPYRDYPSLLDDLLRILKTVMSNTMRREAIKTLGILGAIDPYTHK 900
Query: 2701 VFTGSVQSSTAISTALSLPISETDSKDPRQDIIHWFNYEKCTLEEFYPAITIANLMLMMQ 2880
VFTGSVQSSTAISTALSLPISETDSKDPRQDIIHWFNYEKCTLEEFYPAITIANLMLMMQ
Sbjct: 901 VFTGSVQSSTAISTALSLPISETDSKDPRQDIIHWFNYEKCTLEEFYPAITIANLMLMMQ 960
Query: 2881 DEDSQSYAEIAQAIVTIFRSLGDMAPLYTEQVIPRLIEVCRRATESSNRANLREFFLQQL 3060
DEDSQSYAEIAQAIVTIFRSLGDMAPLYTEQVIPRLIEVCRRATESSNRANLREFFLQQL
Sbjct: 961 DEDSQSYAEIAQAIVTIFRSLGDMAPLYTEQVIPRLIEVCRRATESSNRANLREFFLQQL 1020
Query: 3061 ANFVAIIRKHAAPYMPAIFTIIADAWKEDISVKMVVIEVLTDMGTAIGNDFSKYTGELIP 3240
ANFVAIIRKHAAPYMPAIFTIIADAWKEDISVKMVVIEVLTDMGTAIGNDFSKYTGELIP
Sbjct: 1021 ANFVAIIRKHAAPYMPAIFTIIADAWKEDISVKMVVIEVLTDMGTAIGNDFSKYTGELIP 1080
Query: 3241 YLLTVLQTDKTKERVLTVKVMESIQKLTHCIXXXXXXXXXXXXXXXXXFSLKLSIRNTAL 3420
YLLTVLQTDKTKERVLTVKVMESIQKLTHCI FSLKLSIRNTAL
Sbjct: 1081 YLLTVLQTDKTKERVLTVKVMESIQKLTHCIVQHLHLVLPPLLIILDDFSLKLSIRNTAL 1140
Query: 3421 STVLHMTQQVDVSAYAPRMMQSWHHNISTAEMRDXXXXXXXXXXXXXXXFFDIFKRGVDQ 3600
STVLHMTQQVDVSAYAPRMMQSWHHNISTAEMRD FFDIFKRGVDQ
Sbjct: 1141 STVLHMTQQVDVSAYAPRMMQSWHHNISTAEMRDKLLLLLIEIIKQLGKFFDIFKRGVDQ 1200
Query: 3601 KLRDYNLDKSVHYEQYRKLAQRAQMSRDVLTSSVFAGSNGNIQYSSTQAGMRGQANNVYA 3780
KLRDYNLDKSVHYEQYRKLAQRAQMSRDVLTSSVFAGSNGNIQYSSTQAGMRGQANNVYA
Sbjct: 1201 KLRDYNLDKSVHYEQYRKLAQRAQMSRDVLTSSVFAGSNGNIQYSSTQAGMRGQANNVYA 1260
Query: 3781 NNDLHERLMNGSIDSGASRQDNRDDYYRYGVEEK--KEVPKVAPTTARPTSELVTVQITK 3954
NNDLHERLMNGSIDSGASRQDNRDDYYRYGVEEK +EVPKVAPTTARPTSELVTVQITK
Sbjct: 1261 NNDLHERLMNGSIDSGASRQDNRDDYYRYGVEEKISEEVPKVAPTTARPTSELVTVQITK 1320
Query: 3955 QRLNKDALMPQWKNENLTSKDEWLQWLMKIRIGFLTYGSSPSLRAASSLGDQHPHLARDL 4134
QRLNKDALMPQWKNENLTSKDEWLQWLMKIRIGFLTYGSSPSLRAASSLGDQHPHLARDL
Sbjct: 1321 QRLNKDALMPQWKNENLTSKDEWLQWLMKIRIGFLTYGSSPSLRAASSLGDQHPHLARDL 1380
Query: 4135 FPAAFMSVWTELDSDVQNDLTSCLLRAISTGIPELIQTILNLAEFMDHSEKGPLPISHDV 4314
FPAAFMSVWTELDSDVQNDLTSCLLRAISTGIPELIQTILNLAEFMDHSEKGPLPISHDV
Sbjct: 1381 FPAAFMSVWTELDSDVQNDLTSCLLRAISTGIPELIQTILNLAEFMDHSEKGPLPISHDV 1440
Query: 4315 LGRWAEQTKAFAKACRYKEMSVLKKSGSMQTTFTRKVKLEPNDCQSLITYANKLNVQEEA 4494
LGRWAEQTKAFAKACRYKEMSVLKKSGSMQTTFTRKVKLEPNDCQSLITYANKLNVQEEA
Sbjct: 1441 LGRWAEQTKAFAKACRYKEMSVLKKSGSMQTTFTRKVKLEPNDCQSLITYANKLNVQEEA 1500
Query: 4495 AGVVRYAERNEMNFQMRGRWYEKLNEWEKALGAYELEEKKKSSCPNLQVYDEKDHLMTPX 4674
AGVVRYAERNEMNFQMRGRWYEKLNEWEKALGAYELEEKKKSSCPNLQVYDEKDHLMTP
Sbjct: 1501 AGVVRYAERNEMNFQMRGRWYEKLNEWEKALGAYELEEKKKSSCPNLQVYDEKDHLMTPE 1560
Query: 4675 XXXXXXXXRMHEMRCLEALGRWDELNSKSVVWADQRGNRNDSVRDEINKKQLDHKMAVIA 4854
RMHEMRCLEALGRWDELNSKSVVWADQRGNRNDSVRDEINKKQLDHKMAVIA
Sbjct: 1561 EAATAEEARMHEMRCLEALGRWDELNSKSVVWADQRGNRNDSVRDEINKKQLDHKMAVIA 1620
Query: 4855 ARGAWAVDNWERMADYVSVISENTQDGAMLRAVVAVHNDENTKAMGLIEKVREMIDSELT 5034
ARGAWAVDNWERMADYVSVISENTQDGAMLRAVVAVHNDENTKAMGLIEKVREMIDSELT
Sbjct: 1621 ARGAWAVDNWERMADYVSVISENTQDGAMLRAVVAVHNDENTKAMGLIEKVREMIDSELT 1680
Query: 5035 AMANESYERAYIPMVSVQQMAELEEAIEYKTRPERRPRIALLWSRRLQGCRRNVEQWQRL 5214
AMANESYERAYIPMVSVQQMAELEEAIEYKTRPERRPRIALLWSRRLQGCRRNVEQWQRL
Sbjct: 1681 AMANESYERAYIPMVSVQQMAELEEAIEYKTRPERRPRIALLWSRRLQGCRRNVEQWQRL 1740
Query: 5215 IMLRGLVLSPQEMHPLRVKFSSMCRKQGKNSMSRAVLRELLSLPANSDLVRAKAPFDKPL 5394
IMLRGLVLSPQEMHPLRVKFSSMCRKQGKNSMSRAVLRELLSLPANSDLVRAKAPFDKPL
Sbjct: 1741 IMLRGLVLSPQEMHPLRVKFSSMCRKQGKNSMSRAVLRELLSLPANSDLVRAKAPFDKPL 1800
Query: 5395 LVLALAKQLYQDDHKDEAIRALEDLANHWNKRINPIPKATGRELIPPSTKEPARICAKVL 5574
LVLALAKQLYQDDHKDEAIRALEDLANHWNKRINPIPKATGRELIPPSTKEPARICAKVL
Sbjct: 1801 LVLALAKQLYQDDHKDEAIRALEDLANHWNKRINPIPKATGRELIPPSTKEPARICAKVL 1860
Query: 5575 LKLGEWTELKSKTSNNMQVGELSFVRQQVSPQYRTKESRTPETIAFENTINYYQQATQYD 5754
LKLGEWTELKSKTSNNMQVGELSFVRQQVSPQYRTKESRTPETIAFENTINYYQQATQYD
Sbjct: 1861 LKLGEWTELKSKTSNNMQVGELSFVRQQVSPQYRTKESRTPETIAFENTINYYQQATQYD 1920
Query: 5755 PGWHKVWHKLASTHFYAVCRERPHPTTVISXXXXXXXXKKMHIXXXXXXXXXXXXXXXXX 5934
PGWHKVWHKLASTHFYAVCRERPHPTTVIS KKMHI
Sbjct: 1921 PGWHKVWHKLASTHFYAVCRERPHPTTVISPPQQPQQPKKMHIPPVTRATSPPPPAQKSP 1980
Query: 5935 XXXXFHSITEPLSVIIDYXXXXXXXXXXXXXXXXAYLSSNSSLPPQHHHVSPLSNDSPSN 6114
FHSITEPLS DY AYLSSNSSLPPQHHHVSPLSNDSPSN
Sbjct: 1981 QPAPFHSITEPLS---DYPVPPPLGSLVGLPPMPAYLSSNSSLPPQHHHVSPLSNDSPSN 2037
Query: 6115 SAENKLYLKHAAHAVRCFAKALMCSPGSRLEDTLRLMQLWFDHGDDKDQDVYFALTETIF 6294
SAENKLYLKHAAHAVRCFAKALMCSPGSRLEDTLRLMQLWFDHGDDKDQDVYFALTETIF
Sbjct: 2038 SAENKLYLKHAAHAVRCFAKALMCSPGSRLEDTLRLMQLWFDHGDDKDQDVYFALTETIF 2097
Query: 6295 DLPVTTWLEAIPQLMARLDCPDDQKSVQLVLRVLCEIARHRPQAVIYALTVASRSKDVHR 6474
DLPVTTWLEAIPQLMARLDCPDDQKSVQLVLRVLCEIARHRPQAVIYALTVASRSKDVHR
Sbjct: 2098 DLPVTTWLEAIPQLMARLDCPDDQKSVQLVLRVLCEIARHRPQAVIYALTVASRSKDVHR 2157
Query: 6475 SKNAGTVLEKMMEYHSKLVREASLVTEELVRCAILWHEQWHDALDDASRVYFHRRLQDNN 6654
SKNAGTVLEKMMEYHSKLVREASLVTEELVRCAILWHEQWHDALDDASRVYFH DNN
Sbjct: 2158 SKNAGTVLEKMMEYHSKLVREASLVTEELVRCAILWHEQWHDALDDASRVYFH----DNN 2213
Query: 6655 VQAMFDALRNMNDLMQKGAPTTMKEHSFQQTYSSDLKEAGRYVQAFESSGNVKDLNQAWE 6834
VQAMFDALRNMNDLMQKGAPTTMKEHSFQQTYSSDLKEAGRYVQAFESSGNVKDLNQAWE
Sbjct: 2214 VQAMFDALRNMNDLMQKGAPTTMKEHSFQQTYSSDLKEAGRYVQAFESSGNVKDLNQAWE 2273
Query: 6835 IYCSVFKKLRDQLATLNSLDLVYVSPNLVSAKDLELVVPGTYDPSAPIVSIQSFSSKMNV 7014
IYCSVFKKLRDQLATLNSLDLVYVSPNLVSAKDLELVVPGTYDPSAPIVSIQSFSSKMNV
Sbjct: 2274 IYCSVFKKLRDQLATLNSLDLVYVSPNLVSAKDLELVVPGTYDPSAPIVSIQSFSSKMNV 2333
Query: 7015 ITSKQRPRKMVIRGSNGLDYQFLLKGHEDPRQDERVMQLFGLVNTLLANNSETCRRNLTI 7194
ITSKQRPRKMVIRGSNGLDYQFLLKGHEDPRQDERVMQLFGLVNTLLANNSETCRRNLTI
Sbjct: 2334 ITSKQRPRKMVIRGSNGLDYQFLLKGHEDPRQDERVMQLFGLVNTLLANNSETCRRNLTI 2393
Query: 7195 QRYSIVALSKDSGLIGWVPNCDTLHTLVKEYREKKAKIPLSIEHKTLQKLSLETEHLTLM 7374
QRYSIVALSKDSGLIGWVPNCDTLHTLVKEYREKKAKIPLSIEHKTLQKLSLETEHLTLM
Sbjct: 2394 QRYSIVALSKDSGLIGWVPNCDTLHTLVKEYREKKAKIPLSIEHKTLQKLSLETEHLTLM 2453
Query: 7375 QKLQLFESALSVTQGEDLRHVLWLKSPSSEVWFDRRTNYTRSVACMSMVGYILGLGDRHP 7554
QKLQLFESALSVTQGEDLRHVLWLKSPSSEVWFDRRTNYTRSVACMSMVGYILGLGDRHP
Sbjct: 2454 QKLQLFESALSVTQGEDLRHVLWLKSPSSEVWFDRRTNYTRSVACMSMVGYILGLGDRHP 2513
Query: 7555 SNLMLDRLTGKVVHIDFGDCFEVAMLREKFPERVPFRLTRMLINAMEVTGLDGVYNYTAE 7734
SNLMLDRLTGKVVHIDFGDCFEVAMLREKFPERVPFRLTRMLINAMEVTGLDGVYNYTAE
Sbjct: 2514 SNLMLDRLTGKVVHIDFGDCFEVAMLREKFPERVPFRLTRMLINAMEVTGLDGVYNYTAE 2573
Query: 7735 RVLKMLRTNQESLLAVLEAFVYDPVINWRLVEGMKKDPKTRKDTGGRQNMAGAVLPSSST 7914
RVLKMLRTNQESLLAVLEAFVYDPVINWRLVEGMKKDPKTRKDTGGRQNMAGAVLPSSST
Sbjct: 2574 RVLKMLRTNQESLLAVLEAFVYDPVINWRLVEGMKKDPKTRKDTGGRQNMAGAVLPSSST 2633
Query: 7915 TDSIMETIKRKLDGTEFVHTDGSTPPEPLQVTEQLAMLTEQATSPLNLCQSYIGWCPFW 8091
TDSIMETIKRKLDGTEFVHTDGSTPPEPLQVTEQLAMLTEQATSPLNLCQSYIGWCPFW
Sbjct: 2634 TDSIMETIKRKLDGTEFVHTDGSTPPEPLQVTEQLAMLTEQATSPLNLCQSYIGWCPFW 2692
>gi|39595871|emb|CAE67374.1| Hypothetical protein CBG12850
[Caenorhabditis briggsae]
Length = 1563
Score = 2456 bits (6366), Expect = 0.0
Identities = 1257/1562 (80%), Positives = 1371/1562 (87%), Gaps = 4/1562 (0%)
Frame = +1
Query: 454 NGNGLDEDTVKMASKALAFLIATCKSYAAELVDRCLDHCHEWLGQNVPHSQQP-KNQQEI 630
NG G+DE T+++ASKALAFLI TCK+YAAELVDRCLDHC EWL +VP Q P +NQ+++
Sbjct: 3 NGGGIDEQTIQLASKALAFLITTCKTYAAELVDRCLDHCQEWL-HHVPSYQPPVQNQKDL 61
Query: 631 DQI--RRLAASHLSRELALATPTAFFLRVNLFFKYIFNAVRDKNPAVRIAGIDALHVVLT 804
I RRLA++HLSRE+ALATPTAFFLRVNLFFKYIF A++DK VR+AGIDALH VLT
Sbjct: 62 TLIEQRRLASAHLSREIALATPTAFFLRVNLFFKYIFFAIKDKQVLVRLAGIDALHTVLT 121
Query: 805 IVSQREAKNKTEWFKKCFDEALEGQPNPSQKDDLDRWHAVALILNELLRISDQRFELIRC 984
IV + + K +CF EAL N D D+WH+VALILNELLRISD RFE++RC
Sbjct: 122 IVHNEKPRIKPN---ECFSEALTANTNHQSSDIHDKWHSVALILNELLRISDSRFEMVRC 178
Query: 985 ESSQFIKQKFLKEDEEEGVEWLVLTKQQTIVESVTARKLVLERFPKILDCVRQIIPLANK 1164
ESS F+KQK+L+EDE++GVEWL L+KQ IVESVT+RKLV+E F KI+DCVRQ+IPLANK
Sbjct: 179 ESSNFVKQKYLREDEDDGVEWLCLSKQPVIVESVTSRKLVVENFSKIIDCVRQMIPLANK 238
Query: 1165 TSSTKQQSSIYLNTVLMQLLPRICAFPQCDRTFQTISFDTSFTILQRNAVAAPAIGMMML 1344
+ KQ I+LNTVLMQLLPRICAFPQ DRTFQT+++DT+F +LQ+N++ APA+GMMML
Sbjct: 239 VQN-KQMPGIHLNTVLMQLLPRICAFPQSDRTFQTLAYDTAFHVLQKNSIGAPALGMMML 297
Query: 1345 SNPDVHATHIEKTISFISAAIKK-TTNSDVLDNYFTFLFLFVDAYHEQVTTQIKAIIPQL 1521
NPDVH+ IE TI+FISA IKK TT+SD LD++FTFLFLFVD+YHE+VT QIKAIIPQL
Sbjct: 298 HNPDVHSNRIEATINFISAEIKKVTTSSDALDSFFTFLFLFVDSYHEKVTAQIKAIIPQL 357
Query: 1522 MDITLSRSLANVLKMIMMRIPKLRLNVQDGVMASVYQTLTGSLIPPKSEPIGRPASPKAI 1701
MDI LSRSLANVLKMIMMRIPKLRLNVQDGVMASVY TLTG IPPKSEP GRP SPK I
Sbjct: 358 MDIPLSRSLANVLKMIMMRIPKLRLNVQDGVMASVYHTLTGLPIPPKSEPTGRPPSPKLI 417
Query: 1702 LQKAETDPKELQRIVLAVDVLGEFYFSRGALQRIMQYVADYYLTADNVEIRLAAVSSCCE 1881
LQ+A +PKELQRIVLAVDVLGEFYFSRGALQRIMQYVADYYLTADNVEIRLAAVSSCCE
Sbjct: 418 LQRAIEEPKELQRIVLAVDVLGEFYFSRGALQRIMQYVADYYLTADNVEIRLAAVSSCCE 477
Query: 1882 MVVPFVGVYKKVTSDKRNSLLQTIYGVLRAVCSVIVNDQDVRVRMQVISCFGQMPRPFLA 2061
MVVPFVGVYKKVT+DKRNSLLQTIYGVLRAVCSVIVND DVRVRMQVISCFGQMPRPFLA
Sbjct: 478 MVVPFVGVYKKVTTDKRNSLLQTIYGVLRAVCSVIVNDPDVRVRMQVISCFGQMPRPFLA 537
Query: 2062 HLAQPEMLEVQFMALHDEKLEMQQACVTLLGRLAELNPAXXXXXXXXXXXXXXSQMQQSG 2241
HLAQPEMLEVQFMALHDEKLEMQQACVTLLGRLAELNPA SQM QSG
Sbjct: 538 HLAQPEMLEVQFMALHDEKLEMQQACVTLLGRLAELNPALVLPRLRLMLLETLSQMMQSG 597
Query: 2242 QARLEQHSAKMIAQLAKQSPKFMRPYVGSLMIAMIPKLRNDQKYAEVTAQVLNAVSEIAV 2421
QARLEQHSAKMIAQLAKQSPKFMRPYVGSLM+A+IPK+RNDQKYAEVTAQVL+A+SEI+V
Sbjct: 598 QARLEQHSAKMIAQLAKQSPKFMRPYVGSLMVALIPKMRNDQKYAEVTAQVLHAISEISV 657
Query: 2422 IGGAEIVKNLKPLFEKLTHMINDSSSLHKREAALRAIGGICRSTAYVVDPYRDYPSLLDD 2601
IGGAEIVKNLKPLFEKLTHMINDSS+LHKREAALRAIGGICRSTAYVVDPYRDYP+LLDD
Sbjct: 658 IGGAEIVKNLKPLFEKLTHMINDSSNLHKREAALRAIGGICRSTAYVVDPYRDYPTLLDD 717
Query: 2602 LLRILKTVMSNTMRREAIKTLGILGAIDPYTHKVFTGSVQSSTAISTALSLPISETDSKD 2781
LLRILKTVMSNTMRRE IKTLGILGAIDPYTHKVFTGSVQS+TAISTALSLP++ DSKD
Sbjct: 718 LLRILKTVMSNTMRREVIKTLGILGAIDPYTHKVFTGSVQSATAISTALSLPMNAEDSKD 777
Query: 2782 PRQDIIHWFNYEKCTLEEFYPAITIANLMLMMQDEDSQSYAEIAQAIVTIFRSLGDMAPL 2961
PRQDIIHWFNYEKCTL+EFYPAITIANLM+MMQDEDSQ++AEIAQAIVTIFRSLG+MAPL
Sbjct: 778 PRQDIIHWFNYEKCTLDEFYPAITIANLMIMMQDEDSQNFAEIAQAIVTIFRSLGEMAPL 837
Query: 2962 YTEQVIPRLIEVCRRATESSNRANLREFFLQQLANFVAIIRKHAAPYMPAIFTIIADAWK 3141
YTEQV+PRLIEVCR+ TE SN REFFLQQLA FVAII+KHAAPYMPAIFTIIADAWK
Sbjct: 838 YTEQVVPRLIEVCRKTTEQSNHGTNREFFLQQLAIFVAIIKKHAAPYMPAIFTIIADAWK 897
Query: 3142 EDISVKMVVIEVLTDMGTAIGNDFSKYTGELIPYLLTVLQTDKTKERVLTVKVMESIQKL 3321
EDISVKMVVI+VLT+MGTAIGNDFSKYTGELIPYLLTVLQTDKTKERVLTVKVMESI+ L
Sbjct: 898 EDISVKMVVIQVLTEMGTAIGNDFSKYTGELIPYLLTVLQTDKTKERVLTVKVMESIRPL 957
Query: 3322 THCIXXXXXXXXXXXXXXXXXFSLKLSIRNTALSTVLHMTQQVDVSAYAPRMMQSWHHNI 3501
T+CI SLKLSIR TAL TVLHMTQQVDVSAYAPRMMQSWHHNI
Sbjct: 958 TYCIVQHLHLVLPPILIILDDISLKLSIRQTALDTVLHMTQQVDVSAYAPRMMQSWHHNI 1017
Query: 3502 STAEMRDXXXXXXXXXXXXXXXFFDIFKRGVDQKLRDYNLDKSVHYEQYRKLAQRAQMSR 3681
AEMRD FFDIFKRGVDQKLR++ LDKSVHYE YRKLAQRAQMSR
Sbjct: 1018 KVAEMRDKLLLLLIEIIKQLGKFFDIFKRGVDQKLREHALDKSVHYETYRKLAQRAQMSR 1077
Query: 3682 DVLTSSVFAGSNGNIQYSSTQAGMRGQANNVYANNDLHERLMNGSIDSGASRQDNRDDYY 3861
DV+TSSVFAGSNGN+Q S QA +RG N+Y NN+LHERL+NGS+DS SR NRDDYY
Sbjct: 1078 DVITSSVFAGSNGNLQ--SAQAAIRGDPGNIYLNNELHERLLNGSMDSANSRHGNRDDYY 1135
Query: 3862 RYGVEEKKEVPKVAPTTARPTSELVTVQITKQRLNKDALMPQWKNENLTSKDEWLQWLMK 4041
++G+E+KKE PKVAPTTAR TSELVT+QITKQRLNKD +M QWKNE+LTSKDEWLQWL+K
Sbjct: 1136 QFGLEDKKETPKVAPTTARSTSELVTIQITKQRLNKDLVMSQWKNEHLTSKDEWLQWLVK 1195
Query: 4042 IRIGFLTYGSSPSLRAASSLGDQHPHLARDLFPAAFMSVWTELDSDVQNDLTSCLLRAIS 4221
IRIGFL GSSPSLRAASSLGDQ+PHLARDLFPAAFMSVWTELDS+VQ DLT+CLLRA+S
Sbjct: 1196 IRIGFLKSGSSPSLRAASSLGDQYPHLARDLFPAAFMSVWTELDSEVQKDLTACLLRAVS 1255
Query: 4222 TGIPELIQTILNLAEFMDHSEKGPLPISHDVLGRWAEQTKAFAKACRYKEMSVLKKSGSM 4401
TGIPELIQTILNLAEFMDHSEKGPLPI+HDVLG WAEQTKAFAKACRYKEMSVLK S +
Sbjct: 1256 TGIPELIQTILNLAEFMDHSEKGPLPITHDVLGMWAEQTKAFAKACRYKEMSVLKSSETA 1315
Query: 4402 QTTFTRKVKLEPNDCQSLITYANKLNVQEEAAGVVRYAERNEMNFQMRGRWYEKLNEWEK 4581
TF RK+ L PNDCQSLITYANKLNVQEEAAGVVRYAERN+MNFQ RGRWYEKLNEWEK
Sbjct: 1316 PMTFRRKITLRPNDCQSLITYANKLNVQEEAAGVVRYAERNDMNFQRRGRWYEKLNEWEK 1375
Query: 4582 ALGAYELEEKKKSSCPNLQVYDEKDHLMTPXXXXXXXXXRMHEMRCLEALGRWDELNSKS 4761
AL AY +EE K+SC NLQ D+ D + TP +MHEMRCLEAL RWDELN+KS
Sbjct: 1376 ALDAY-MEE--KNSCTNLQNLDKND-VETPEKAAAAEEAKMHEMRCLEALARWDELNAKS 1431
Query: 4762 VVWADQRGNRNDSVRDEINKKQLDHKMAVIAARGAWAVDNWERMADYVSVISENTQDGAM 4941
+WA+QR R+DS+RDEINKKQLDHKMAVIAARGAWAVDNWERMA+YVSVISENTQDGAM
Sbjct: 1432 AIWAEQRSQRSDSIRDEINKKQLDHKMAVIAARGAWAVDNWERMAEYVSVISENTQDGAM 1491
Query: 4942 LRAVVAVHNDENTKAMGLIEKVREMIDSELTAMANESYERAYIPMVSVQQMAELEEAIEY 5121
LRAVVAVHNDENTKAMGLIEKVREMIDSELTAMANESYERAYIPMVSVQQMAELEEAIEY
Sbjct: 1492 LRAVVAVHNDENTKAMGLIEKVREMIDSELTAMANESYERAYIPMVSVQQMAELEEAIEY 1551
Query: 5122 KT 5127
K+
Sbjct: 1552 KS 1553
>gi|4826730|ref|NP_004949.1| FK506 binding protein 12-rapamycin
associated protein 1; FK506 binding protein 12-rapamycin
associated protein 2; rapamycin target protein;
FKBP12-rapamycin complex-associated protein 1;
FKBP-rapamycin associated protein [Homo sapiens]
gi|1169735|sp|P42345|FRAP_HUMAN FKBP-rapamycin associated protein
(FRAP) (Rapamycin target protein)
gi|2135120|pir||S45340 FKBP-rapamycin-associated protein (FRAP) -
human
gi|508482|gb|AAA58486.1| FKBP-rapamycin associated protein
Length = 2549
Score = 1429 bits (3698), Expect = 0.0
Identities = 949/2765 (34%), Positives = 1423/2765 (51%), Gaps = 116/2765 (4%)
Frame = +1
Query: 145 ALASQYRSRITENRDANQRQAARELSRYVRSELKDEPNTFSDAFLNAIDGRTDIASQSAI 324
++ Q+ S + + + +AA+EL YV EL++ S F + ++ I
Sbjct: 20 SVLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEESTRFYDQLNHH--------I 71
Query: 325 YNCMKSNSNIDQKRAGIYLIVCLAETHSGNVIR---YANYLLKMLNNGNGLDEDTVKMAS 495
+ + S+S+ ++++ GI I L GN R +ANYL +L + D ++MAS
Sbjct: 72 FELV-SSSDANERKGGILAIASLIGVEGGNATRIGRFANYLRNLLPSN---DPVVMEMAS 127
Query: 496 KALAFLIATCKSYAAELVDRCLDHCHEWLGQNVPHSQQPKNQQEIDQIRRLAASHLSREL 675
KA+ L ++ AE V+ + EWLG + +N+ RR AA + REL
Sbjct: 128 KAIGRLAMAGDTFTAEYVEFEVKRALEWLGAD-------RNEG-----RRHAAVLVLREL 175
Query: 676 ALATPTAFFLRVNLFFKYIFNAVRDKNPAVRIAGIDALHVVLTIVSQREAKN--KTEWFK 849
A++ PT FF +V FF IF AV D A+R + AL L + +QRE K K +W++
Sbjct: 176 AISVPTFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQREPKEMQKPQWYR 235
Query: 850 KCFDEALEGQPNPSQKDDL----DRWHAVALILNELLRISDQRFELIRCE-----SSQFI 1002
F+EA +G K+ DR H LILNEL+RIS E +R E Q +
Sbjct: 236 HTFEEAEKGFDETLAKEKGMNRDDRIHGALLILNELVRISSMEGERLREEMEEITQQQLV 295
Query: 1003 KQKFLKEDEEEGVEWLVLTK-------------------------------------QQT 1071
K+ K+ G + +T + T
Sbjct: 296 HDKYCKDLMGFGTKPRHITPFTSFQAVQPQQSNALVGLLGYSSHQGLMGFGTSPSPAKST 355
Query: 1072 IVESVTARKLVLERFPKILDCVRQIIPLANKTSSTKQQSSIYLNTVLMQLLPRICAFPQC 1251
+VES R L+ E+F ++ V + N +S Q + ++ LLPR+ AF
Sbjct: 356 LVESRCCRDLMEEKFDQVCQWV---LKCRNSKNSLIQMT-------ILNLLPRLAAFRPS 405
Query: 1252 DRTFQTISFDTSFTIL------QRNAVAAPAIGMMMLSNPDVHATHIEKTISFISAAI-- 1407
T DT +L + A A+G++ ++ ++ + + I AA+
Sbjct: 406 AFTDTQYLQDTMNHVLSCVKKEKERTAAFQALGLLSVAVRSEFKVYLPRVLDIIRAALPP 465
Query: 1408 -----KKTTNSDVLDNYFTFLFLFVDAYHEQVTTQIKAIIPQLMDITLSRSLANVLKMIM 1572
K+ V FT + + A + IK ++ ++ + LS +L VL +
Sbjct: 466 KDFAHKRQKAMQVDATVFTCISMLARAMGPGIQQDIKELLEPMLAVGLSPALTAVLYDLS 525
Query: 1573 MRIPKLRLNVQDGVMASVYQTLTGSLIPPKSEPIGRPASPKAILQKAET-------DPKE 1731
+IP+L+ ++QDG++ + L +P+ P PK + + + + +
Sbjct: 526 RQIPQLKKDIQDGLLKMLSLVLM-------HKPLRHPGMPKGLAHQLASPGLTTLPEASD 578
Query: 1732 LQRIVLAVDVLGEFYFSRGALQRIMQYVADYYLTADNVEIRLAAVSSCCEMVVPFVGVYK 1911
+ I LA+ LG F F +L + +++ AD++L +++ EIR+ A +C ++ P + +
Sbjct: 579 VGSITLALRTLGSFEFEGHSLTQFVRHCADHFLNSEHKEIRMEAARTCSRLLTPSIHLIS 638
Query: 1912 KVTSDKRNSLLQTIYGVLRAVCSVIVNDQDVRVRMQVISCFGQMPRPFLAHLAQPEMLEV 2091
+ +Q + VL + V + D D +R V++ + F AHLAQ E L+
Sbjct: 639 GHAHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDER---FDAHLAQAENLQA 695
Query: 2092 QFMALHDEKLEMQQACVTLLGRLAELNPAXXXXXXXXXXXXXXSQMQQSGQARLEQHSAK 2271
F+AL+D+ E+++ + +GRL+ +NPA ++++ SG R+++ SA+
Sbjct: 696 LFVALNDQVFEIRELAICTVGRLSSMNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSAR 755
Query: 2272 MIAQLAKQSPKFMRPYVGSLMIAMIPKLRNDQKYAE--VTAQVLNAVSEIAVIGGAEIVK 2445
M+ L +P+ +RPY+ ++ A+I KL++ V VL + E+A + G E+ K
Sbjct: 756 MLGHLVSNAPRLIRPYMEPILKALILKLKDPDPDPNPGVINNVLATIGELAQVSGLEMRK 815
Query: 2446 NLKPLFEKLTHMINDSSSLHKREAALRAIGGICRSTAYVVDPYRDYPSLLDDLLRILKTV 2625
+ LF + M+ DSS L KR+ AL +G + ST YVV+PYR YP+LL+ LL LKT
Sbjct: 816 WVDELFIIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTE 875
Query: 2626 MSNTMRREAIKTLGILGAIDPYTHKVFTGSV-QSSTAISTALSLPISETDSKDPRQDIIH 2802
+ RREAI+ LG+LGA+DPY HKV G + QS A + +LS S DS D +
Sbjct: 876 QNQGTRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEM- 934
Query: 2803 WFNYEKCTLEEFYPAITIANLMLMMQDED-SQSYAEIAQAIVTIFRSLGDMAPLYTEQVI 2979
N L+EFYPA+++ LM + +D+ S + + QAI IF+SLG + QV+
Sbjct: 935 LVNMGNLPLDEFYPAVSMVALMRIFRDQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVM 994
Query: 2980 PRLIEVCRRATESSNRANLREFFLQQLANFVAIIRKHAAPYMPAIFTIIADAWKEDISVK 3159
P + V R + +REF QQL V+ ++ H PYM I T++ + W + S++
Sbjct: 995 PTFLNVIRVCDGA-----IREFLFQQLGMLVSFVKSHIRPYMDEIVTLMREFWVMNTSIQ 1049
Query: 3160 MVVIEVLTDMGTAIGNDFSKYTGELIPYLLTVLQTDKTKERVLTVKVMESIQKLTHCIXX 3339
+I ++ + A+G +F Y +LIP++L V D + R++++K++ +IQ +
Sbjct: 1050 STIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDNSPGRIVSIKLLAAIQLFGANLDD 1109
Query: 3340 XXXXXXXXXXXXXXXFSLKLSIRNTALSTVLHMTQQVDVSAYAPRMMQSWHHNISTA-EM 3516
L R AL TV +T+ +D + YA R++ + + E+
Sbjct: 1110 YLHLLLPPIVKLFDAPEAPLPSRKAALETVDRLTESLDFTDYASRIIHPIVRTLDQSPEL 1169
Query: 3517 RDXXXXXXXXXXXXXXXFFDIFKRGVDQKLRDYNLDKSVHYEQYRKLAQRAQMSRDVLTS 3696
R + IF V++ L + +++++Y DVL
Sbjct: 1170 RSTAMDTLSSLVFQLGKKYQIFIPMVNKVLVRHR----INHQRY-----------DVLIC 1214
Query: 3697 SVFAGSNGNIQYSSTQAGMRGQANNVYANNDLHERLMNGSIDSGASRQDNRDDYYRYGVE 3876
+ G Y+ + +Y H L +G D+ AS
Sbjct: 1215 RIVKG------YTLAD---EEEDPLIYQ----HRMLRSGQGDALAS-------------- 1247
Query: 3877 EKKEVPKVAPTTARPTSELVTVQITKQRLNKDALMPQWKNENLTSKDEWLQWLMKIRIGF 4056
P P +L I Q+ W SKD+WL+WL ++ +
Sbjct: 1248 --------GPVETGPMKKLHVSTINLQKA--------WGAARRVSKDDWLEWLRRLSLEL 1291
Query: 4057 LTYGSSPSLRAASSLGDQHPHLARDLFPAAFMSVWTELDSDVQNDLTSCLLRAI-STGIP 4233
L SSPSLR+ +L + +ARDLF AAF+S W+EL+ D Q++L + A+ S I
Sbjct: 1292 LKDSSSPSLRSCWALAQAYNPMARDLFNAAFVSCWSELNEDQQDELIRSIELALTSQDIA 1351
Query: 4234 ELIQTILNLAEFMDHSEKGPLPISHD----VLGRWAEQTKAFAKACRYKEMSVLKKSGSM 4401
E+ QT+LNLAEFM+HS+KGPLP+ D +LG A + +A+AKA YKE+ K
Sbjct: 1352 EVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEFQKGP--- 1408
Query: 4402 QTTFTRKVKLEPNDCQSLITYANKLNVQEEAAGVVRYAERNEMNFQMRGRWYEKLNEWEK 4581
P +SLI+ NKL E AAGV+ YA ++ +++ WYEKL+EWE
Sbjct: 1409 ----------TPAILESLISINNKLQQPEAAAGVLEYAMKHFGELEIQATWYEKLHEWED 1458
Query: 4582 ALGAYELEEKKKSSCPNLQVYDEKDHLMTPXXXXXXXXXRMHEMRCLEALGRWDELNSKS 4761
AL AY+ + P L + MRCLEALG W +L+ +
Sbjct: 1459 ALVAYDKKMDTNKDDPELM---------------------LGRMRCLEALGEWGQLHQQC 1497
Query: 4762 VVWADQRGNRNDSVRDEINKKQLDHKMAVIAARGAWAVDNWERMADYVSVISENTQDGAM 4941
+ V DE K MA +AA AW + W+ M +Y +I +T DGA
Sbjct: 1498 C-------EKWTLVNDETQAK-----MARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAF 1545
Query: 4942 LRAVVAVHNDENTKAMGLIEKVREMIDSELTAMANESYERAYIPMVSVQQMAELEEAIEY 5121
RAV+A+H D + A I+K R+++D+ELTAMA ESY RAY MVS ++ELEE I+Y
Sbjct: 1546 YRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQY 1605
Query: 5122 KTRPERRPRIALLWSRRLQGCRRNVEQWQRLIMLRGLVLSPQEMHPLRVKFSSMCRKQGK 5301
K PERR I +W RLQGC+R VE WQ+++M+R LV+SP E +K++S+C K G+
Sbjct: 1606 KLVPERREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGR 1665
Query: 5302 NSMSRAVLRELLSLPANSDLVRAKAPFDKPLLVLALAKQLYQDDHKDEAIRALEDLANHW 5481
+++ L LL + + L P P + A K +++ K +A + ++
Sbjct: 1666 LALAHKTLVLLLGVDPSRQLDHP-LPTVHPQVTYAYMKNMWKSARKIDAFQHMQHFVQTM 1724
Query: 5482 NKRINPIPKATGRELIPPSTKEPARICAKVLLKLGEWTELKSKTSNNMQVGELSFVRQQV 5661
++ ++ +E ++ A+ LKLGEW N+Q
Sbjct: 1725 QQQAQHAIATEDQQ----HKQELHKLMARCFLKLGEW-------QLNLQ----------- 1762
Query: 5662 SPQYRTKESRTPETIAFENTINYYQQATQYDPGWHKVWHKLASTHFYAVCRERPHPTTVI 5841
ES P+ + YY AT++D W+K WH A +F AV + H
Sbjct: 1763 ----GINESTIPKVL------QYYSAATEHDRSWYKAWHAWAVMNFEAVLHYK-HQNQAR 1811
Query: 5842 SXXXXXXXXKKMHIXXXXXXXXXXXXXXXXXXXXXFHSITEPLSVIIDYXXXXXXXXXXX 6021
+I +S +E S
Sbjct: 1812 DEKKKLRHASGANITNATTAATTAATATTTASTEGSNSESEAES---------------- 1855
Query: 6022 XXXXXAYLSSNSSLPPQHHHVSPLSNDSPSNSAENKLYLKHAAHAVRCFAKALMCSPGSR 6201
+ NS P SPL + + K L + AV+ F +++ S G+
Sbjct: 1856 --------TENSPTP------SPLQKKVTEDLS--KTLLMYTVPAVQGFFRSISLSRGNN 1899
Query: 6202 LEDTLRLMQLWFDHGDDKDQDVYFALTETIFDLPVTTWLEAIPQLMARLDCPDDQKSVQL 6381
L+DTLR++ LWFD+G D V AL E + + + TWL+ IPQL+AR+D P +L
Sbjct: 1900 LQDTLRVLTLWFDYGHWPD--VNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVG-RL 1956
Query: 6382 VLRVLCEIARHRPQAVIYALTVASRSKDVHRSKNAGTVLEKMMEYHSKLVREASLVTEEL 6561
+ ++L +I R+ PQA+IY LTVAS+S R A +L+ M E+ + LV++A +V+EEL
Sbjct: 1957 IHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHSNTLVQQAMMVSEEL 2016
Query: 6562 VRCAILWHEQWHDALDDASRVYFHRRLQDNNVQAMFDALRNMNDLMQKGAPTTMKEHSFQ 6741
+R AILWHE WH+ L++ASR+YF R NV+ MF+ L ++ +M++G P T+KE SF
Sbjct: 2017 IRVAILWHEMWHEGLEEASRLYFGER----NVKGMFEVLEPLHAMMERG-PQTLKETSFN 2071
Query: 6742 QTYSSDLKEAGRYVQAFESSGNVKDLNQAWEIYCSVFKKLRDQLATLNSLDLVYVSPNLV 6921
Q Y DL EA + + + SGNVKDL QAW++Y VF+++ QL L SL+L YVSP L+
Sbjct: 2072 QAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLL 2131
Query: 6922 SAKDLELVVPGTYDPSAPIVSIQSFSSKMNVITSKQRPRKMVIRGSNGLDYQFLLKGHED 7101
+DLEL VPGTYDP+ PI+ IQS + + VITSKQRPRK+ + GSNG ++ FLLKGHED
Sbjct: 2132 MCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHED 2191
Query: 7102 PRQDERVMQLFGLVNTLLANNSETCRRNLTIQRYSIVALSKDSGLIGWVPNCDTLHTLVK 7281
RQDERVMQLFGLVNTLLAN+ + R+NL+IQRY+++ LS +SGLIGWVP+CDTLH L++
Sbjct: 2192 LRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIR 2251
Query: 7282 EYREKKAKIPLSIEHKTLQKLSLETEHLTLMQKLQLFESALSVTQGEDLRHVLWLKSPSS 7461
+YREKK KI L+IEH+ + +++ + +HLTLMQK+++FE A++ T G+DL +LWLKSPSS
Sbjct: 2252 DYREKK-KILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSS 2310
Query: 7462 EVWFDRRTNYTRSVACMSMVGYILGLGDRHPSNLMLDRLTGKVVHIDFGDCFEVAMLREK 7641
EVWFDRRTNYTRS+A MSMVGYILGLGDRHPSNLMLDRL+GK++HIDFGDCFEVAM REK
Sbjct: 2311 EVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREK 2370
Query: 7642 FPERVPFRLTRMLINAMEVTGLDGVYNYTAERVLKMLRTNQESLLAVLEAFVYDPVINWR 7821
FPE++PFRLTRML NAMEVTGLDG Y T V+++LR +++S++AVLEAFVYDP++NWR
Sbjct: 2371 FPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWR 2430
Query: 7822 LVEGMKKDPK---TRKDTGG----------------RQNMAGAVLPSS------------ 7908
L++ K K TR D+ G +P S
Sbjct: 2431 LMDTNTKGNKRSRTRTDSYSAGQSVEILDGVELGEPAHKKTGTTVPESIHSFIGDGLVKP 2490
Query: 7909 ----STTDSIMETIKRKLDGTEFVHTDGSTPPEPLQVTEQLAMLTEQATSPLNLCQSYIG 8076
I+ ++ KL G +F H D L V Q+ +L +QATS NLCQ YIG
Sbjct: 2491 EALNKKAIQIINRVRDKLTGRDFSHDD------TLDVPTQVELLIKQATSHENLCQCYIG 2544
Query: 8077 WCPFW 8091
WCPFW
Sbjct: 2545 WCPFW 2549
>gi|744518|prf||2014422A FKBP-rapamycin-associated protein
Length = 2549
Score = 1422 bits (3681), Expect = 0.0
Identities = 948/2765 (34%), Positives = 1420/2765 (51%), Gaps = 116/2765 (4%)
Frame = +1
Query: 145 ALASQYRSRITENRDANQRQAARELSRYVRSELKDEPNTFSDAFLNAIDGRTDIASQSAI 324
++ Q+ S + + + +AA+EL YV EL++ S F + ++ I
Sbjct: 20 SVLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEESTRFYDQLNHH--------I 71
Query: 325 YNCMKSNSNIDQKRAGIYLIVCLAETHSGNVIR---YANYLLKMLNNGNGLDEDTVKMAS 495
+ + S+S+ + ++ GI I L GN R +ANYL +L + D ++MAS
Sbjct: 72 FELV-SSSDANFRKGGILAIASLIGVEGGNATRIGRFANYLRNLLPSN---DPVVMEMAS 127
Query: 496 KALAFLIATCKSYAAELVDRCLDHCHEWLGQNVPHSQQPKNQQEIDQIRRLAASHLSREL 675
KA+ L ++ AE V+ + EWLG + +N+ RR AA + REL
Sbjct: 128 KAIGRLAMAGDTFTAEYVEFEVKRALEWLGAD-------RNEG-----RRHAAVLVLREL 175
Query: 676 ALATPTAFFLRVNLFFKYIFNAVRDKNPAVRIAGIDALHVVLTIVSQREAKN--KTEWFK 849
A++ PT FF +V FF IF AV D A+R + AL L + +QRE K K +W++
Sbjct: 176 AISVPTFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQREPKEMQKPQWYR 235
Query: 850 KCFDEALEGQPNPSQKDDL----DRWHAVALILNELLRISDQRFELIRCE-----SSQFI 1002
F+EA +G K+ DR H LILNEL+RIS E +R E Q +
Sbjct: 236 HTFEEAEKGFDETLAKEKGMNRDDRIHGALLILNELVRISSMEGERLREEMEEITQQQLV 295
Query: 1003 KQKFLKEDEEEGVEWLVLTK-------------------------------------QQT 1071
K+ K+ G + +T + T
Sbjct: 296 HDKYCKDLMGFGTKPRHITPFTSFQAVQPQQSNALVGLLGYSSHQGLMGFGTSPSPAKST 355
Query: 1072 IVESVTARKLVLERFPKILDCVRQIIPLANKTSSTKQQSSIYLNTVLMQLLPRICAFPQC 1251
+VES R L+ E+F ++ V + N +S Q + ++ LLPR+ AF
Sbjct: 356 LVESRCCRDLMEEKFDQVCQWV---LKCRNSKNSLIQMT-------ILNLLPRLAAFRPS 405
Query: 1252 DRTFQTISFDTSFTIL------QRNAVAAPAIGMMMLSNPDVHATHIEKTISFISAAI-- 1407
T DT +L + A A+G++ ++ ++ + + I AA+
Sbjct: 406 AFTDTQYLQDTMNHVLSCVKKEKERTAAFQALGLLSVAVRSEFKVYLPRVLDIIRAALPP 465
Query: 1408 -----KKTTNSDVLDNYFTFLFLFVDAYHEQVTTQIKAIIPQLMDITLSRSLANVLKMIM 1572
K+ V FT + + A + IK ++ ++ + LS +L VL +
Sbjct: 466 KDFAHKRQKAMQVDATVFTCISMLARAMGPGIQQDIKELLEPMLAVGLSPALTAVLYDLS 525
Query: 1573 MRIPKLRLNVQDGVMASVYQTLTGSLIPPKSEPIGRPASPKAILQKAET-------DPKE 1731
+IP+L+ ++QDG++ + L +P+ P PK + + + + +
Sbjct: 526 RQIPQLKKDIQDGLLKMLSLVLM-------HKPLRHPGMPKGLAHQLASPGLTTLPEASD 578
Query: 1732 LQRIVLAVDVLGEFYFSRGALQRIMQYVADYYLTADNVEIRLAAVSSCCEMVVPFVGVYK 1911
+ I LA+ LG F F +L + +++ AD++L +++ EIR+ A +C ++ P + +
Sbjct: 579 VGSITLALRTLGSFEFEGHSLTQFVRHCADHFLNSEHKEIRMEAARTCSRLLTPSIHLIS 638
Query: 1912 KVTSDKRNSLLQTIYGVLRAVCSVIVNDQDVRVRMQVISCFGQMPRPFLAHLAQPEMLEV 2091
+ +Q + VL + V + D D +R V++ + F AHLAQ E L+
Sbjct: 639 GHAHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDER---FDAHLAQAENLQA 695
Query: 2092 QFMALHDEKLEMQQACVTLLGRLAELNPAXXXXXXXXXXXXXXSQMQQSGQARLEQHSAK 2271
F+AL+D+ E+++ + +GRL+ +NPA ++++ SG R+++ SA+
Sbjct: 696 LFVALNDQVFEIRELAICTVGRLSSMNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSAR 755
Query: 2272 MIAQLAKQSPKFMRPYVGSLMIAMIPKLRNDQKYAE--VTAQVLNAVSEIAVIGGAEIVK 2445
M+ L +P+ +RPY+ ++ A+I KL++ V VL + E+A + G E+ K
Sbjct: 756 MLGHLVSNAPRLIRPYMEPILKALILKLKDPDPDPNPGVINNVLATIGELAQVSGLEMRK 815
Query: 2446 NLKPLFEKLTHMINDSSSLHKREAALRAIGGICRSTAYVVDPYRDYPSLLDDLLRILKTV 2625
+ LF + M+ DSS L KR+ AL +G + ST YVV+PYR YP+LL+ LL LKT
Sbjct: 816 WVDELFIIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTE 875
Query: 2626 MSNTMRREAIKTLGILGAIDPYTHKVFTGSV-QSSTAISTALSLPISETDSKDPRQDIIH 2802
+ RREAI+ LG+LGA+DPY HKV G + QS A + +LS S DS D +
Sbjct: 876 QNQGTRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEM- 934
Query: 2803 WFNYEKCTLEEFYPAITIANLMLMMQDED-SQSYAEIAQAIVTIFRSLGDMAPLYTEQVI 2979
N L+EFYPA+++ LM + +D+ S + + QAI IF+SLG + QV+
Sbjct: 935 LVNMGNLPLDEFYPAVSMVALMRIFRDQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVM 994
Query: 2980 PRLIEVCRRATESSNRANLREFFLQQLANFVAIIRKHAAPYMPAIFTIIADAWKEDISVK 3159
P + V R + +REF QQL V+ ++ H PYM I T++ + W + S++
Sbjct: 995 PTFLNVIRVCDGA-----IREFLFQQLGMLVSFVKSHIRPYMDEIVTLMREFWVMNTSIQ 1049
Query: 3160 MVVIEVLTDMGTAIGNDFSKYTGELIPYLLTVLQTDKTKERVLTVKVMESIQKLTHCIXX 3339
+I ++ + A+G +F Y +LIP++L V D + R++++K++ +IQ +
Sbjct: 1050 STIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDNSPGRIVSIKLLAAIQLFGANLDD 1109
Query: 3340 XXXXXXXXXXXXXXXFSLKLSIRNTALSTVLHMTQQVDVSAYAPRMMQSWHHNISTA-EM 3516
L R AL TV +T+ +D + YA R++ + + E+
Sbjct: 1110 YLHLLLPPIVKLFDAPEAPLPSRKAALETVDRLTESLDFTDYASRIIHPIVRTLDQSPEL 1169
Query: 3517 RDXXXXXXXXXXXXXXXFFDIFKRGVDQKLRDYNLDKSVHYEQYRKLAQRAQMSRDVLTS 3696
R + IF V++ L + +++++Y DVL
Sbjct: 1170 RSTAMDTLSSLVFQLGKKYQIFIPMVNKVLVRHR----INHQRY-----------DVLIC 1214
Query: 3697 SVFAGSNGNIQYSSTQAGMRGQANNVYANNDLHERLMNGSIDSGASRQDNRDDYYRYGVE 3876
+ G Y+ + +Y H L +G D+ AS
Sbjct: 1215 RIVKG------YTLAD---EEEDPLIYQ----HRMLRSGQGDALAS-------------- 1247
Query: 3877 EKKEVPKVAPTTARPTSELVTVQITKQRLNKDALMPQWKNENLTSKDEWLQWLMKIRIGF 4056
P P +L I Q+ W SKD+WL+WL ++ +
Sbjct: 1248 --------GPVETGPMKKLHYSTINLQKA--------WGAARRVSKDDWLEWLRRLSLEL 1291
Query: 4057 LTYGSSPSLRAASSLGDQHPHLARDLFPAAFMSVWTELDSDVQNDLTSCLLRAI-STGIP 4233
L SSPSLR+ +L + +ARDLF AAF+S W+EL+ D Q++L + A+ S I
Sbjct: 1292 LKDSSSPSLRSCWALAQAYNPMARDLFNAAFVSCWSELNEDQQDELIRSIELALTSQDIA 1351
Query: 4234 ELIQTILNLAEFMDHSEKGPLPISHD----VLGRWAEQTKAFAKACRYKEMSVLKKSGSM 4401
E+ QT+LNLAEFM+HS+KGPLP+ D +LG A + +A+AKA YKE+ K
Sbjct: 1352 EVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEFQKGP--- 1408
Query: 4402 QTTFTRKVKLEPNDCQSLITYANKLNVQEEAAGVVRYAERNEMNFQMRGRWYEKLNEWEK 4581
P +SLI+ NKL E AAGV+ YA ++ +++ WYEKL+EWE
Sbjct: 1409 ----------TPAILESLISINNKLQQPEAAAGVLEYAMKHFGELEIQATWYEKLHEWED 1458
Query: 4582 ALGAYELEEKKKSSCPNLQVYDEKDHLMTPXXXXXXXXXRMHEMRCLEALGRWDELNSKS 4761
AL AY+ + P L + MRCLEALG W +L+ +
Sbjct: 1459 ALVAYDKKMDTNKDDPELM---------------------LGRMRCLEALGEWGQLHQQC 1497
Query: 4762 VVWADQRGNRNDSVRDEINKKQLDHKMAVIAARGAWAVDNWERMADYVSVISENTQDGAM 4941
+ V DE K MA +AA AW + W+ M +Y +I +T DGA
Sbjct: 1498 C-------EKWTLVNDETQAK-----MARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAF 1545
Query: 4942 LRAVVAVHNDENTKAMGLIEKVREMIDSELTAMANESYERAYIPMVSVQQMAELEEAIEY 5121
RAV+A+H D + A I+K R+++D+ELTAMA ESY RAY MVS ++ELEE I+Y
Sbjct: 1546 YRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQY 1605
Query: 5122 KTRPERRPRIALLWSRRLQGCRRNVEQWQRLIMLRGLVLSPQEMHPLRVKFSSMCRKQGK 5301
K PERR I +W RLQGC+R VE WQ+++M+R LV+SP E +K++S+C K G+
Sbjct: 1606 KLVPERREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGR 1665
Query: 5302 NSMSRAVLRELLSLPANSDLVRAKAPFDKPLLVLALAKQLYQDDHKDEAIRALEDLANHW 5481
+++ L LL + + L P P + A K +++ K +A + ++
Sbjct: 1666 LALAHKTLVLLLGVDPSRQLDHP-LPTVHPQVTYAYMKNMWKSARKIDAFQHMQHFVQTM 1724
Query: 5482 NKRINPIPKATGRELIPPSTKEPARICAKVLLKLGEWTELKSKTSNNMQVGELSFVRQQV 5661
++ ++ +E ++ A+ LKLGEW N+Q
Sbjct: 1725 QQQAQHAIATEDQQ----HKQELHKLMARCFLKLGEW-------QLNLQ----------- 1762
Query: 5662 SPQYRTKESRTPETIAFENTINYYQQATQYDPGWHKVWHKLASTHFYAVCRERPHPTTVI 5841
ES P+ + YY AT++D W+K WH A +F AV + H
Sbjct: 1763 ----GINESTIPKVL------QYYSAATEHDRSWYKAWHAWAVMNFEAVLHYK-HQNQAR 1811
Query: 5842 SXXXXXXXXKKMHIXXXXXXXXXXXXXXXXXXXXXFHSITEPLSVIIDYXXXXXXXXXXX 6021
+I +S +E S
Sbjct: 1812 DEKKKLRHASGANITNATTAATTAATATTTASTEGSNSESEAES---------------- 1855
Query: 6022 XXXXXAYLSSNSSLPPQHHHVSPLSNDSPSNSAENKLYLKHAAHAVRCFAKALMCSPGSR 6201
+ NS P SPL + + K L + AV+ F +++ S G+
Sbjct: 1856 --------TENSPTP------SPLQKKVTEDLS--KTLLMYTVPAVQGFFRSISLSRGNN 1899
Query: 6202 LEDTLRLMQLWFDHGDDKDQDVYFALTETIFDLPVTTWLEAIPQLMARLDCPDDQKSVQL 6381
L+DTLR++ LWFD+G D V AL E + + + TWL+ IPQL+AR+D P +L
Sbjct: 1900 LQDTLRVLTLWFDYGHWPD--VNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVG-RL 1956
Query: 6382 VLRVLCEIARHRPQAVIYALTVASRSKDVHRSKNAGTVLEKMMEYHSKLVREASLVTEEL 6561
+ ++L +I R+ PQA+IY LTVAS+S R A +L+ M E+ + LV++A +V+EEL
Sbjct: 1957 IHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHSNTLVQQAMMVSEEL 2016
Query: 6562 VRCAILWHEQWHDALDDASRVYFHRRLQDNNVQAMFDALRNMNDLMQKGAPTTMKEHSFQ 6741
+R AILWHE WH+ L++ASR+YF R NV+ MF+ L ++ +M++G P T+KE SF
Sbjct: 2017 IRVAILWHEMWHEGLEEASRLYFGER----NVKGMFEVLEPLHAMMERG-PQTLKETSFN 2071
Query: 6742 QTYSSDLKEAGRYVQAFESSGNVKDLNQAWEIYCSVFKKLRDQLATLNSLDLVYVSPNLV 6921
Q Y DL EA + + + SGNVKDL QAW++Y VF+++ QL L SL+L YVSP L+
Sbjct: 2072 QAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLL 2131
Query: 6922 SAKDLELVVPGTYDPSAPIVSIQSFSSKMNVITSKQRPRKMVIRGSNGLDYQFLLKGHED 7101
+DLEL VPGTYDP+ PI+ IQS + + VITSKQRPRK+ + GSNG ++ FLLKGHED
Sbjct: 2132 MCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHED 2191
Query: 7102 PRQDERVMQLFGLVNTLLANNSETCRRNLTIQRYSIVALSKDSGLIGWVPNCDTLHTLVK 7281
RQDERVMQLFGLVNTLLAN+ + R+NL+ QRY+++ LS +SGLIGWVP+CDTLH L++
Sbjct: 2192 LRQDERVMQLFGLVNTLLANDPTSLRKNLSTQRYAVIPLSTNSGLIGWVPHCDTLHALIR 2251
Query: 7282 EYREKKAKIPLSIEHKTLQKLSLETEHLTLMQKLQLFESALSVTQGEDLRHVLWLKSPSS 7461
+YREKK KI L+IEH+ + +++ + +HLTLMQK+ +FE A++ T G+DL +LWLKSPSS
Sbjct: 2252 DYREKK-KILLNIEHRIMLRMAPDYDHLTLMQKVFVFEHAVNNTAGDDLAKLLWLKSPSS 2310
Query: 7462 EVWFDRRTNYTRSVACMSMVGYILGLGDRHPSNLMLDRLTGKVVHIDFGDCFEVAMLREK 7641
EVWFDRRTNYTRS+A MSMVGYILGLGDRHPSNLMLDRL+GK++HIDFGDCFEVAM REK
Sbjct: 2311 EVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREK 2370
Query: 7642 FPERVPFRLTRMLINAMEVTGLDGVYNYTAERVLKMLRTNQESLLAVLEAFVYDPVINWR 7821
FPE++PFRLTRML NAMEVTGLDG Y T V+++LR +++S++AVLEAFVYDP++NWR
Sbjct: 2371 FPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWR 2430
Query: 7822 LVEGMKKDPK---TRKDTGG----------------RQNMAGAVLPSS------------ 7908
L++ K K TR D+ G +P S
Sbjct: 2431 LMDTNTKGNKRSRTRTDSYSAGQSVEILDGVELGEPAHKKTGTTVPESIHSFIGDGLVKP 2490
Query: 7909 ----STTDSIMETIKRKLDGTEFVHTDGSTPPEPLQVTEQLAMLTEQATSPLNLCQSYIG 8076
I+ ++ KL G +F H D L V Q+ +L +QATS NLCQ YIG
Sbjct: 2491 EALNKKAIQIINRVRDKLTGRDFSHDD------TLDVPTQVELLIKQATSHENLCQCYIG 2544
Query: 8077 WCPFW 8091
WCPFW
Sbjct: 2545 WCPFW 2549
>gi|3282239|gb|AAC39933.1| rapamycin associated protein FRAP2 [Homo
sapiens]
Length = 2548
Score = 1392 bits (3603), Expect = 0.0
Identities = 934/2767 (33%), Positives = 1405/2767 (50%), Gaps = 118/2767 (4%)
Frame = +1
Query: 145 ALASQYRSRITENRDANQRQAARELSRYVRSELKDEPNTFSDAFLNAIDGRTDIASQSAI 324
++ Q+ S + + + +AA+EL YV EL++ S F + ++ I
Sbjct: 20 SVLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEESTRFYDQLNHH--------I 71
Query: 325 YNCMKSNSNIDQKRAGIYLIVCLAETHSGNVIR---YANYLLKMLNNGNGLDEDTVKMAS 495
+ + S+S+ ++++ GI I L GN R +ANYL +L + D ++MAS
Sbjct: 72 FELV-SSSDANERKGGILAIASLIGVEGGNATRIGRFANYLRNLLPSN---DPVVMEMAS 127
Query: 496 KALAFLIATCKSYAAELVDRCLDHCHEWLGQNVPHSQQPKNQQEIDQIRRLAASHLSREL 675
KA+ L ++ AE V+ + EWLG + +N+ RR AA + REL
Sbjct: 128 KAIGRLAMAGDTFTAEYVEFEVKRALEWLGAD-------RNEG-----RRHAAVLVLREL 175
Query: 676 ALATPTAFFLRVNLFFKYIFNAVRDKNPAVRIAGIDALHVVLTIVSQREAKN--KTEWFK 849
A++ PT FF +V FF IF AV D A+R + AL L + +QRE K K +W++
Sbjct: 176 AISVPTFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQREPKEMQKPQWYR 235
Query: 850 KCFDEALEGQPNPSQKDDL----DRWHAVALILNELLRISDQRFELIRCE-----SSQFI 1002
F+EA +G K+ DR H LILNEL+RIS E +R E Q +
Sbjct: 236 HTFEEAEKGFDETLAKEKGMNRDDRIHGALLILNELVRISSMEGERLREEMEEITQQQLV 295
Query: 1003 KQKFLKEDEEEGVEWLVLTK-------------------------------------QQT 1071
K+ K+ G + +T T
Sbjct: 296 HDKYCKDLMGFGTKPRHITPFTSFQAVQPQQSNALVGLLGYSSHQGLMGFGTSPSPANST 355
Query: 1072 IVESVTARKLVLERFPKILDCVRQIIPLANKTSSTKQQSSIYLNTVLMQLLPRICAFPQC 1251
+VE+ R L+ E+F ++ V + + + + ++ LLPR+ AF
Sbjct: 356 LVENRCCRNLMEEKFDQVCQWVLKC----------RNSKNSLIQLTILNLLPRLAAFRPS 405
Query: 1252 DRTFQTISFDTSFTIL------QRNAVAAPAIGMMMLSNPDVHATHIEKTISFISAAI-- 1407
T DT +L + A A+G++ ++ ++ + + I A+
Sbjct: 406 AFTDTQYLQDTMNHVLSCVKKEKELTAAFQALGLLSVAVRSEFKVYLPRGVEIIRGALPP 465
Query: 1408 -----KKTTNSDVLDNYFTFLFLFVDAYHEQVTTQIKAIIPQLMDITLSRSLANVLKMIM 1572
K+ V +F + + A + IK ++ ++ + +S +L VL +
Sbjct: 466 KDFAHKRQKAMQVDATFFNCISMVARAMGPGIQQDIKELLEPMLAVGISPALTAVLYDLS 525
Query: 1573 MRIPKLRLNVQDGVMASVYQTLTGSLIPPKSEPIGRPASPKAILQKAET-------DPKE 1731
+IP+L+ ++QDGV+ + L +P+ P PK + + + + +
Sbjct: 526 RQIPQLKKDIQDGVLKMLSLVLM-------HKPLCHPGMPKGLAHQLASPGLTTLPEASD 578
Query: 1732 LQRIVLAVDVLGEFYFSRGALQRIMQYVADYYLTADNVEIRLAAVSSCCEMVVPFVGVYK 1911
+ I LA+ LG F F +L + +++ AD++L +++ EIR+ A +C ++ P + +
Sbjct: 579 VGSITLALRTLGSFEFEGHSLTQFVRHCADHFLNSEHKEIRMEAARTCSRLLTPSIHLIS 638
Query: 1912 KVTSDKRNSLLQTIYGVLRAVCSVIVNDQDVRVRMQVISCFGQMPRPFLAHLAQPEMLEV 2091
+ +Q + VL + V + D D +R V++ + F AHLAQ E L+
Sbjct: 639 GHAHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDER---FDAHLAQAENLQA 695
Query: 2092 QFMALHDEKLEMQQACVTLLGRLAELNPAXXXXXXXXXXXXXXSQMQQSGQARLEQHSAK 2271
F+AL+D+ E+++ + +GRL+ +NPA ++++ SG R+++ SA+
Sbjct: 696 LFVALNDQVFEIRELAICTVGRLSSMNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSAR 755
Query: 2272 MIAQLAKQSPKFMRPYVGSLMIAMIPKLRNDQKYAE--VTAQVLNAVSEIAVIGGAEIVK 2445
M+ L +P+ +RPY+ ++ A+I KL++ V VL + E+A + G E+ K
Sbjct: 756 MLGHLVSNAPRLIRPYMEPILKALILKLKDPDPDPNPGVINNVLATIGELAQVSGLEMRK 815
Query: 2446 NLKPLFEKLTHMINDSSSLHKREAALRAIGGICRSTAYVVDPYRDYPSLLDDLLRILKTV 2625
+ LF + M+ DSS L KR+ AL +G + ST YVV+PYR YP+LL+ LL LKT
Sbjct: 816 WVDELFIIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTE 875
Query: 2626 MSNTMRREAIKTLGILGAIDPYTHKVFTGSV-QSSTAISTALSLPISETDSKDPRQDIIH 2802
+ RREAI+ LG+LGA+DPY HKV G + QS A + +LS S DS D +
Sbjct: 876 QNQGTRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEM- 934
Query: 2803 WFNYEKCTLEEFYPAITIANLMLMMQDEDSQSYAEIAQAIVTIFRSLGDM---APLYTEQ 2973
N L+EFYPA+++ L + + S + G P
Sbjct: 935 LVNMGNLPLDEFYPAVSMVALADLPRPVTLSSSHHGCPGHHLHLQVPGTQMCAVPAPGHA 994
Query: 2974 VIPRLIEVCRRATESSNRANLREFFLQQLANFVAIIRKHAAPYMPAIFTIIADAWKEDIS 3153
+P +I VC A +REF QQL V+ ++ H PYM I T++ + W + S
Sbjct: 995 HVPYVIRVCDGA--------IREFLFQQLGMLVSFVKSHIRPYMDEIVTLMREFWVMNTS 1046
Query: 3154 VKMVVIEVLTDMGTAIGNDFSKYTGELIPYLLTVLQTDKTKERVLTVKVMESIQKLTHCI 3333
++ +I ++ + A+G +F Y +L P++L V D + R++++K++ +IQ +
Sbjct: 1047 IQSTIILLIEQIVVALGGEFKLYLPQLSPHMLRVFMHDNSPGRIVSIKLLAAIQLFGANL 1106
Query: 3334 XXXXXXXXXXXXXXXXXFSLKLSIRNTALSTVLHMTQQVDVSAYAPRMMQSWHHNISTA- 3510
L R AL TV +T+ +D + YA R++ + +
Sbjct: 1107 DDYLHLLLPPIVKLFDAPEAPLPSRKAALETVDRLTESLDFTDYASRIIHPIVRTLDQSP 1166
Query: 3511 EMRDXXXXXXXXXXXXXXXFFDIFKRGVDQKLRDYNLDKSVHYEQYRKLAQRAQMSRDVL 3690
E+R + IF V++ L + +++++Y DVL
Sbjct: 1167 ELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLVRHR----INHQRY-----------DVL 1211
Query: 3691 TSSVFAGSNGNIQYSSTQAGMRGQANNVYANNDLHERLMNGSIDSGASRQDNRDDYYRYG 3870
+ G Y+ + +Y H L +G D+ AS
Sbjct: 1212 ICRIVKG------YTLAD---EEEDPLIYQ----HRMLRSGQGDALAS------------ 1246
Query: 3871 VEEKKEVPKVAPTTARPTSELVTVQITKQRLNKDALMPQWKNENLTSKDEWLQWLMKIRI 4050
P P +L I Q+ W SKD+WL+WL ++ +
Sbjct: 1247 ----------GPVETGPMKKLHVSTINLQKA--------WGAARRVSKDDWLEWLRRLSL 1288
Query: 4051 GFLTYGSSPSLRAASSLGDQHPHLARDLFPAAFMSVWTELDSDVQNDLTSCLLRAI-STG 4227
L SSPSLR+ +L + +ARDLF AAF+S W+EL+ D Q++L + A+ S
Sbjct: 1289 ELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVSCWSELNEDQQDELIRSIELALTSQD 1348
Query: 4228 IPELIQTILNLAEFMDHSEKGPLPISHD----VLGRWAEQTKAFAKACRYKEMSVLKKSG 4395
I E+ QT+LNLAEFM+HS+KGPLP+ D +LG A + +A+AKA YKE+ K
Sbjct: 1349 IAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEFQKGP- 1407
Query: 4396 SMQTTFTRKVKLEPNDCQSLITYANKLNVQEEAAGVVRYAERNEMNFQMRGRWYEKLNEW 4575
P +SLI+ NKL E AAGV+ YA ++ +++ WYEKL+EW
Sbjct: 1408 ------------TPAILESLISINNKLQQPEAAAGVLEYAMKHFGELEIQATWYEKLHEW 1455
Query: 4576 EKALGAYELEEKKKSSCPNLQVYDEKDHLMTPXXXXXXXXXRMHEMRCLEALGRWDELNS 4755
E AL AY+ + P L + MRCLEALG W +L+
Sbjct: 1456 EDALVAYDKKMDTNKDDPELM---------------------LGRMRCLEALGEWGQLHQ 1494
Query: 4756 KSVVWADQRGNRNDSVRDEINKKQLDHKMAVIAARGAWAVDNWERMADYVSVISENTQDG 4935
+ + V DE K MA +AA AW + W+ M +Y +I +T DG
Sbjct: 1495 QCC-------EKWTLVNDETQAK-----MARMAAAAAWGLGQWDSMEEYTCMIPRDTHDG 1542
Query: 4936 AMLRAVVAVHNDENTKAMGLIEKVREMIDSELTAMANESYERAYIPMVSVQQMAELEEAI 5115
A RAV+A+H D + A I+K R+++D+ELTAMA ESY RAY MVS ++ELEE I
Sbjct: 1543 AFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVI 1602
Query: 5116 EYKTRPERRPRIALLWSRRLQGCRRNVEQWQRLIMLRGLVLSPQEMHPLRVKFSSMCRKQ 5295
+YK PERR I +W RLQGC+R VE WQ+++M+R LV+SP E +K++S+C K
Sbjct: 1603 QYKLVPERREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKS 1662
Query: 5296 GKNSMSRAVLRELLSLPANSDLVRAKAPFDKPLLVLALAKQLYQDDHKDEAIRALEDLAN 5475
G+ +++ L LL + + L P P + A K +++ K +A + ++
Sbjct: 1663 GRLALAHKTLVLLLGVDPSRQLDHP-LPTVHPQVTYAYMKNMWKSARKIDAFQHMQHFVQ 1721
Query: 5476 HWNKRINPIPKATGRELIPPSTKEPARICAKVLLKLGEWTELKSKTSNNMQVGELSFVRQ 5655
++ ++ +E ++ A+ LKLGEW N+Q
Sbjct: 1722 TMQQQAQHAIATEDQQ----HKQELHKLMARCFLKLGEW-------QLNLQ--------- 1761
Query: 5656 QVSPQYRTKESRTPETIAFENTINYYQQATQYDPGWHKVWHKLASTHFYAVCRERPHPTT 5835
ES P+ + YY AT++D W+K WH A +F AV + H
Sbjct: 1762 ------GINESTIPKVL------QYYSAATEHDRSWYKAWHAWAVMNFEAVLHYK-HQNQ 1808
Query: 5836 VISXXXXXXXXKKMHIXXXXXXXXXXXXXXXXXXXXXFHSITEPLSVIIDYXXXXXXXXX 6015
+I +S +E S
Sbjct: 1809 ARDEKKKLRHASGANITNATTAATTAATATTTASTEGSNSESEAES-------------- 1854
Query: 6016 XXXXXXXAYLSSNSSLPPQHHHVSPLSNDSPSNSAENKLYLKHAAHAVRCFAKALMCSPG 6195
+ NS P SPL + + K L + AV+ F +++ S G
Sbjct: 1855 ----------TENSPTP------SPLQKKVTEDLS--KTLLMYTVPAVQGFFRSISLSRG 1896
Query: 6196 SRLEDTLRLMQLWFDHGDDKDQDVYFALTETIFDLPVTTWLEAIPQLMARLDCPDDQKSV 6375
+ L+DTLR++ LWFD+G D V AL E + + + TWL+ IPQL+AR+D P
Sbjct: 1897 NNLQDTLRVLTLWFDYGHWPD--VNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVG- 1953
Query: 6376 QLVLRVLCEIARHRPQAVIYALTVASRSKDVHRSKNAGTVLEKMMEYHSKLVREASLVTE 6555
+L+ ++L +I R+ PQA+IY LTVAS+S R A +L+ M E+ + LV++A +V+E
Sbjct: 1954 RLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHSNTLVQQAMMVSE 2013
Query: 6556 ELVRCAILWHEQWHDALDDASRVYFHRRLQDNNVQAMFDALRNMNDLMQKGAPTTMKEHS 6735
EL+R AILWHE WH+ L++ASR+YF R NV+ MF+ L ++ +M++G P T+KE S
Sbjct: 2014 ELIRVAILWHEMWHEGLEEASRLYFGER----NVKGMFEVLEPLHAMMERG-PQTLKETS 2068
Query: 6736 FQQTYSSDLKEAGRYVQAFESSGNVKDLNQAWEIYCSVFKKLRDQLATLNSLDLVYVSPN 6915
F Q Y DL EA + + + SGNVKDL QAW++Y VF+++ QL L SL+L YVSP
Sbjct: 2069 FNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPK 2128
Query: 6916 LVSAKDLELVVPGTYDPSAPIVSIQSFSSKMNVITSKQRPRKMVIRGSNGLDYQFLLKGH 7095
L+ +DLEL VPGTYDP+ PI+ IQS + + VITSKQRPRK+ + GSNG ++ FLLKGH
Sbjct: 2129 LLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGH 2188
Query: 7096 EDPRQDERVMQLFGLVNTLLANNSETCRRNLTIQRYSIVALSKDSGLIGWVPNCDTLHTL 7275
ED RQDERVMQLFGLVNTLLAN+ + R+NL+IQRY+++ LS +SGLIGWVP+CDTLH L
Sbjct: 2189 EDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHAL 2248
Query: 7276 VKEYREKKAKIPLSIEHKTLQKLSLETEHLTLMQKLQLFESALSVTQGEDLRHVLWLKSP 7455
+++YREKK KI L+IEH+ + +++ + +HLTLMQK+++FE A++ T G+DL +LWLKSP
Sbjct: 2249 IRDYREKK-KILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSP 2307
Query: 7456 SSEVWFDRRTNYTRSVACMSMVGYILGLGDRHPSNLMLDRLTGKVVHIDFGDCFEVAMLR 7635
SSEVWFDRRTNYTRS+A MSMVGYILGLGDRHPSNLMLDRL+GK++HIDFGDCFEVAM R
Sbjct: 2308 SSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTR 2367
Query: 7636 EKFPERVPFRLTRMLINAMEVTGLDGVYNYTAERVLKMLRTNQESLLAVLEAFVYDPVIN 7815
EKFPE++PFRLTRML NAMEVTGLDG Y T V+++LR +++S++AVLEAFVYDP++N
Sbjct: 2368 EKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLN 2427
Query: 7816 WRLVEGMKKDPK---TRKDTGG----------------RQNMAGAVLPSS---------- 7908
WRL++ K K TR D+ G +P S
Sbjct: 2428 WRLMDTNTKGNKRSRTRTDSYSAGQSVEILDGVELGEPAHKKTGTTVPESIHSFIGDGLV 2487
Query: 7909 ------STTDSIMETIKRKLDGTEFVHTDGSTPPEPLQVTEQLAMLTEQATSPLNLCQSY 8070
I+ ++ KL G +F H D L V Q+ +L +QATS NLCQ Y
Sbjct: 2488 KPEALNKKAIQIINRVRDKLTGRDFSHDD------TLDVPTQVELLIKQATSHENLCQCY 2541
Query: 8071 IGWCPFW 8091
IGWCPFW
Sbjct: 2542 IGWCPFW 2548
>gi|9910228|ref|NP_064393.1| FK506 binding protein 12-rapamycin
associated protein 1; FKBP-rapamycin-associated protein;
FKBP-rapamycin-associated protein FRAP [Mus musculus]
gi|13626915|sp|Q9JLN9|FRAP_MOUSE FKBP-rapamycin associated protein
(FRAP)
gi|8132058|gb|AAF73196.1| FKBP-rapamycin-associated protein FRAP [Mus
musculus]
Length = 2549
Score = 1014 bits (2623), Expect = 0.0
Identities = 590/1412 (41%), Positives = 815/1412 (56%), Gaps = 40/1412 (2%)
Frame = +1
Query: 3976 LMPQWKNENLTSKDEWLQWLMKIRIGFLTYGSSPSLRAASSLGDQHPHLARDLFPAAFMS 4155
L W SKD+WL+WL ++ + L SSPSLR+ +L + +ARDLF AAF+S
Sbjct: 1265 LQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVS 1324
Query: 4156 VWTELDSDVQNDLTSCLLRAI-STGIPELIQTILNLAEFMDHSEKGPLPISHD----VLG 4320
W+EL+ D Q++L + A+ S I E+ QT+LNLAEFM+HS+KGPLP+ D +LG
Sbjct: 1325 CWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLG 1384
Query: 4321 RWAEQTKAFAKACRYKEMSVLKKSGSMQTTFTRKVKLEPNDCQSLITYANKLNVQEEAAG 4500
A + +A+AKA YKE+ K P +SLI+ NKL E A+G
Sbjct: 1385 ERAAKCRAYAKALHYKELEFQKGP-------------TPAILESLISINNKLQQPEAASG 1431
Query: 4501 VVRYAERNEMNFQMRGRWYEKLNEWEKALGAYELEEKKKSSCPNLQVYDEKDHLMTPXXX 4680
V+ YA ++ +++ WYEKL+EWE AL AY+ + P L
Sbjct: 1432 VLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKKMDTNKEDPELM-------------- 1477
Query: 4681 XXXXXXRMHEMRCLEALGRWDELNSKSVVWADQRGNRNDSVRDEINKKQLDHKMAVIAAR 4860
+ MRCLEALG W +L+ + + V DE K MA +AA
Sbjct: 1478 -------LGRMRCLEALGEWGQLHQQCC-------EKWTLVNDETQAK-----MARMAAA 1518
Query: 4861 GAWAVDNWERMADYVSVISENTQDGAMLRAVVAVHNDENTKAMGLIEKVREMIDSELTAM 5040
AW + W+ M +Y +I +T DGA RAV+A+H D + A I+K R+++D+ELTAM
Sbjct: 1519 AAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAM 1578
Query: 5041 ANESYERAYIPMVSVQQMAELEEAIEYKTRPERRPRIALLWSRRLQGCRRNVEQWQRLIM 5220
A ESY RAY MVS ++ELEE I+YK PERR I +W RLQGC+R VE WQ+++M
Sbjct: 1579 AGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREIIRQIWWERLQGCQRIVEDWQKILM 1638
Query: 5221 LRGLVLSPQEMHPLRVKFSSMCRKQGKNSMSRAVLRELLSLPANSDLVRAKAPFDKPLLV 5400
+R LV+SP E +K++S+C K G+ +++ L LL + + L P P +
Sbjct: 1639 VRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHP-LPTAHPQVT 1697
Query: 5401 LALAKQLYQDDHKDEAIRALEDLANHWNKRINPIPKATGRELIPPSTKEPARICAKVLLK 5580
A K +++ K +A + ++ ++ ++ +E ++ A+ LK
Sbjct: 1698 YAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQ----HKQELHKLMARCFLK 1753
Query: 5581 LGEWTELKSKTSNNMQVGELSFVRQQVSPQYRTKESRTPETIAFENTINYYQQATQYDPG 5760
LGEW N+Q ES P+ + YY AT++D
Sbjct: 1754 LGEW-------QLNLQ---------------GINESTIPKVL------QYYSAATEHDRS 1785
Query: 5761 WHKVWHKLASTHFYAVCRERPHPTTVISXXXXXXXXKKMHIXXXXXXXXXXXXXXXXXXX 5940
W+K WH A +F AV + H +I
Sbjct: 1786 WYKAWHAWAVMNFEAVLHYK-HQNQARDEKKKLRHASGANITNATTAATTAASAAAATST 1844
Query: 5941 XXFHSITEPLSVIIDYXXXXXXXXXXXXXXXXAYLSSNSSLPPQHHHVSPLSNDSPSNSA 6120
+S +E S + NS P SPL + +
Sbjct: 1845 EGSNSESEAES------------------------NENSPTP------SPLQKKVTEDLS 1874
Query: 6121 ENKLYLKHAAHAVRCFAKALMCSPGSRLEDTLRLMQLWFDHGDDKDQDVYFALTETIFDL 6300
K L + AV+ F +++ S G+ L+DTLR++ LWFD+G D V AL E + +
Sbjct: 1875 --KTLLLYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPD--VNEALVEGVKAI 1930
Query: 6301 PVTTWLEAIPQLMARLDCPDDQKSVQLVLRVLCEIARHRPQAVIYALTVASRSKDVHRSK 6480
+ TWL+ IPQL+AR+D P +L+ ++L +I R+ PQA+IY LTVAS+S R
Sbjct: 1931 QIDTWLQVIPQLIARIDTPRPLVG-RLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHN 1989
Query: 6481 NAGTVLEKMMEYHSKLVREASLVTEELVRCAILWHEQWHDALDDASRVYFHRRLQDNNVQ 6660
A +L+ M E+ + LV++A +V+EEL+R AILWHE WH+ L++ASR+YF R NV+
Sbjct: 1990 AANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGER----NVK 2045
Query: 6661 AMFDALRNMNDLMQKGAPTTMKEHSFQQTYSSDLKEAGRYVQAFESSGNVKDLNQAWEIY 6840
MF+ L ++ +M++G P T+KE SF Q Y DL EA + + + SGNVKDL QAW++Y
Sbjct: 2046 GMFEVLEPLHAMMERG-PQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLY 2104
Query: 6841 CSVFKKLRDQLATLNSLDLVYVSPNLVSAKDLELVVPGTYDPSAPIVSIQSFSSKMNVIT 7020
VF+++ QL L SL+L YVSP L+ +DLEL VPGTYDP+ PI+ IQS + + VIT
Sbjct: 2105 YHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVIT 2164
Query: 7021 SKQRPRKMVIRGSNGLDYQFLLKGHEDPRQDERVMQLFGLVNTLLANNSETCRRNLTIQR 7200
SKQRPRK+ + GSNG ++ FLLKGHED RQDERVMQLFGLVNTLLAN+ + R+NL+IQR
Sbjct: 2165 SKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQR 2224
Query: 7201 YSIVALSKDSGLIGWVPNCDTLHTLVKEYREKKAKIPLSIEHKTLQKLSLETEHLTLMQK 7380
Y+++ LS +SGLIGWVP+CDTLH L+++YREKK KI L+IEH+ + +++ + +HLTLMQK
Sbjct: 2225 YAVIPLSTNSGLIGWVPHCDTLHALIRDYREKK-KILLNIEHRIMLRMAPDYDHLTLMQK 2283
Query: 7381 LQLFESALSVTQGEDLRHVLWLKSPSSEVWFDRRTNYTRSVACMSMVGYILGLGDRHPSN 7560
+++FE A++ T G+DL +LWLKSPSSEVWFDRRTNYTRS+A MSMVGYILGLGDRHPSN
Sbjct: 2284 VEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSN 2343
Query: 7561 LMLDRLTGKVVHIDFGDCFEVAMLREKFPERVPFRLTRMLINAMEVTGLDGVYNYTAERV 7740
LMLDRL+GK++HIDFGDCFEVAM REKFPE++PFRLTRML NAMEVTGLDG Y T V
Sbjct: 2344 LMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRTTCHTV 2403
Query: 7741 LKMLRTNQESLLAVLEAFVYDPVINWRLVEGMKKDPK---TRKDTGG------------- 7872
+++LR +++S++AVLEAFVYDP++NWRL++ K K TR D+
Sbjct: 2404 MEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDGVEL 2463
Query: 7873 ---RQNMAGAVLPSS----------------STTDSIMETIKRKLDGTEFVHTDGSTPPE 7995
AG +P S I+ ++ KL G +F H D
Sbjct: 2464 GEPAHKKAGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDD------ 2517
Query: 7996 PLQVTEQLAMLTEQATSPLNLCQSYIGWCPFW 8091
L V Q+ +L +QATS NLCQ YIGWCPFW
Sbjct: 2518 TLDVPTQVELLIKQATSHENLCQCYIGWCPFW 2549
Score = 443 bits (1139), Expect = e-122
Identities = 336/1187 (28%), Positives = 568/1187 (47%), Gaps = 75/1187 (6%)
Frame = +1
Query: 145 ALASQYRSRITENRDANQRQAARELSRYVRSELKDEPNTFSDAFLNAIDGRTDIASQSAI 324
++ Q+ S + + + +AA+EL YV EL++ S F + ++ I
Sbjct: 20 SVLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEESTRFYDQLNHH--------I 71
Query: 325 YNCMKSNSNIDQKRAGIYLIVCLAETHSGN---VIRYANYLLKMLNNGNGLDEDTVKMAS 495
+ + S+S+ ++++ GI I L GN + R+ANYL +L + D ++MAS
Sbjct: 72 FELV-SSSDANERKGGILAIASLIGVEGGNSTRIGRFANYLRNLLPSS---DPVVMEMAS 127
Query: 496 KALAFLIATCKSYAAELVDRCLDHCHEWLGQNVPHSQQPKNQQEIDQIRRLAASHLSREL 675
KA+ L ++ AE V+ + EWLG + +N+ RR AA + REL
Sbjct: 128 KAIGRLAMAGDTFTAEYVEFEVKRALEWLGAD-------RNEG-----RRHAAVLVLREL 175
Query: 676 ALATPTAFFLRVNLFFKYIFNAVRDKNPAVRIAGIDALHVVLTIVSQREAKN--KTEWFK 849
A++ PT FF +V FF IF AV D A+R + AL L + +QRE K K +W++
Sbjct: 176 AISVPTFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQREPKEMQKPQWYR 235
Query: 850 KCFDEALEGQPNPSQKDDL----DRWHAVALILNELLRISDQRFELIRCE-----SSQFI 1002
F+EA +G K+ DR H LILNEL+RIS E +R E Q +
Sbjct: 236 HTFEEAEKGFDETLAKEKGMNRDDRIHGALLILNELVRISSMEGERLREEMEEITQQQLV 295
Query: 1003 KQKFLKEDEEEGVEWLVLTK-------------------------------------QQT 1071
K+ K+ G + +T + T
Sbjct: 296 HDKYCKDLMGFGTKPRHITPFTSFQAVQPQQPNALVGLLGYSSPQGLMGFGTSPSPAKST 355
Query: 1072 IVESVTARKLVLERFPKILDCVRQIIPLANKTSSTKQQSSIYLNTVLMQLLPRICAFPQC 1251
+VES R L+ E+F ++ V K S+K + ++ LLPR+ AF
Sbjct: 356 LVESRCCRDLMEEKFDQVCQWVL-------KCRSSKNS---LIQMTILNLLPRLAAFRPS 405
Query: 1252 DRTFQTISFDTSFTIL------QRNAVAAPAIGMMMLSNPDVHATHIEKTISFISAAI-- 1407
T DT +L + A A+G++ ++ ++ + + I AA+
Sbjct: 406 AFTDTQYLQDTMNHVLSCVKKEKERTAAFQALGLLSVAVRSEFKVYLPRVLDIIRAALPP 465
Query: 1408 -----KKTTNSDVLDNYFTFLFLFVDAYHEQVTTQIKAIIPQLMDITLSRSLANVLKMIM 1572
K+ V FT + + A + IK ++ ++ + LS +L VL +
Sbjct: 466 KDFAHKRQKTVQVDATVFTCISMLARAMGPGIQQDIKELLEPMLAVGLSPALTAVLYDLS 525
Query: 1573 MRIPKLRLNVQDGVMASVYQTLTGSLIPPKSEPIGRPASPKAILQKAET-------DPKE 1731
+IP+L+ ++QDG++ + L +P+ P PK + + + + +
Sbjct: 526 RQIPQLKKDIQDGLLKMLSLVLM-------HKPLRHPGMPKGLAHQLASPGLTTLPEASD 578
Query: 1732 LQRIVLAVDVLGEFYFSRGALQRIMQYVADYYLTADNVEIRLAAVSSCCEMVVPFVGVYK 1911
+ I LA+ LG F F +L + +++ AD++L +++ EIR+ A +C ++ P + +
Sbjct: 579 VASITLALRTLGSFEFEGHSLTQFVRHCADHFLNSEHKEIRMEAARTCSCLLTPSIHLIS 638
Query: 1912 KVTSDKRNSLLQTIYGVLRAVCSVIVNDQDVRVRMQVISCFGQMPRPFLAHLAQPEMLEV 2091
+ +Q + VL + V + D D +R V++ + F AHLAQ E L+
Sbjct: 639 GHAHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDER---FDAHLAQAENLQA 695
Query: 2092 QFMALHDEKLEMQQACVTLLGRLAELNPAXXXXXXXXXXXXXXSQMQQSGQARLEQHSAK 2271
F+AL+D+ E+++ + +GRL+ +NPA ++++ SG R+++ SA+
Sbjct: 696 LFVALNDQVFEIRELAICTVGRLSSMNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSAR 755
Query: 2272 MIAQLAKQSPKFMRPYVGSLMIAMIPKLRNDQKYAE--VTAQVLNAVSEIAVIGGAEIVK 2445
M+ L +P+ +RPY+ ++ A+I KL++ V VL + E+A + G E+ K
Sbjct: 756 MLGHLVSNAPRLIRPYMEPILKALILKLKDPDPDPNPGVINNVLATIGELAQVSGLEMRK 815
Query: 2446 NLKPLFEKLTHMINDSSSLHKREAALRAIGGICRSTAYVVDPYRDYPSLLDDLLRILKTV 2625
+ LF + M+ DSS L KR+ AL +G + ST YVV+PYR YP+LL+ LL LKT
Sbjct: 816 WVDELFIIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTE 875
Query: 2626 MSNTMRREAIKTLGILGAIDPYTHKVFTGSV-QSSTAISTALSLPISETDSKDPRQDIIH 2802
+ RREAI+ LG+LGA+DPY HKV G + QS A + +LS S DS D +
Sbjct: 876 QNQGTRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEM- 934
Query: 2803 WFNYEKCTLEEFYPAITIANLMLMMQDED-SQSYAEIAQAIVTIFRSLGDMAPLYTEQVI 2979
N L+EFYPA+++ LM + +D+ S + + QAI IF+SLG + QV+
Sbjct: 935 LVNMGNLPLDEFYPAVSMVALMRIFRDQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVM 994
Query: 2980 PRLIEVCRRATESSNRANLREFFLQQLANFVAIIRKHAAPYMPAIFTIIADAWKEDISVK 3159
P + V R + +REF QQL V+ ++ H PYM I T++ + W + S++
Sbjct: 995 PTFLNVIRVCDGA-----IREFLFQQLGMLVSFVKSHIRPYMDEIVTLMREFWVMNTSIQ 1049
Query: 3160 MVVIEVLTDMGTAIGNDFSKYTGELIPYLLTVLQTDKTKERVLTVKVMESIQKLTHCIXX 3339
+I ++ + A+G +F Y +LIP++L V D ++ R++++K++ +IQ +
Sbjct: 1050 STIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDNSQGRIVSIKLLAAIQLFGANLDD 1109
Query: 3340 XXXXXXXXXXXXXXXFSLKLSIRNTALSTVLHMTQQVDVSAYAPRMM 3480
+ L R AL TV +T+ +D + YA R++
Sbjct: 1110 YLHLLLPPIVKLFDAPEVPLPSRKAALETVDRLTESLDFTDYASRII 1156
>gi|9845251|ref|NP_063971.1| rapamycin and FKBP12 target-1 protein
[Rattus norvegicus]
gi|1169736|sp|P42346|FRAP_RAT FKBP-rapamycin associated protein
(FRAP) (Rapamycin target protein)
gi|1083778|pir||A54837 rapamycin/FKBP12 target 1 - rat
gi|511229|gb|AAA20091.1| rapamycin and FKBP12 target-1 protein
gi|561858|gb|AAA65929.1| rapamycin target
Length = 2549
Score = 1013 bits (2618), Expect = 0.0
Identities = 589/1412 (41%), Positives = 813/1412 (56%), Gaps = 40/1412 (2%)
Frame = +1
Query: 3976 LMPQWKNENLTSKDEWLQWLMKIRIGFLTYGSSPSLRAASSLGDQHPHLARDLFPAAFMS 4155
L W SKD+WL+WL ++ + L SSPSLR+ +L + +ARDLF AAF+S
Sbjct: 1265 LQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVS 1324
Query: 4156 VWTELDSDVQNDLTSCLLRAI-STGIPELIQTILNLAEFMDHSEKGPLPISHD----VLG 4320
W+EL+ D Q++L + A+ S I E+ QT+LNLAEFM+HS+KGPLP+ D +LG
Sbjct: 1325 CWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLG 1384
Query: 4321 RWAEQTKAFAKACRYKEMSVLKKSGSMQTTFTRKVKLEPNDCQSLITYANKLNVQEEAAG 4500
A + +A+AKA YKE+ K P +SLI+ NKL E A+G
Sbjct: 1385 ERAAKCRAYAKALHYKELEFQKGP-------------TPAILESLISINNKLQQPEAASG 1431
Query: 4501 VVRYAERNEMNFQMRGRWYEKLNEWEKALGAYELEEKKKSSCPNLQVYDEKDHLMTPXXX 4680
V+ YA ++ +++ WYEKL+EWE AL AY+ + P L
Sbjct: 1432 VLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPELM-------------- 1477
Query: 4681 XXXXXXRMHEMRCLEALGRWDELNSKSVVWADQRGNRNDSVRDEINKKQLDHKMAVIAAR 4860
+ MRCLEALG W +L+ + + V DE K MA +AA
Sbjct: 1478 -------LGRMRCLEALGEWGQLHQQCC-------EKWTLVNDETQAK-----MARMAAA 1518
Query: 4861 GAWAVDNWERMADYVSVISENTQDGAMLRAVVAVHNDENTKAMGLIEKVREMIDSELTAM 5040
AW + W+ M +Y +I +T DGA RAV+A+H D + A I+K R+++D+ELTAM
Sbjct: 1519 AAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAM 1578
Query: 5041 ANESYERAYIPMVSVQQMAELEEAIEYKTRPERRPRIALLWSRRLQGCRRNVEQWQRLIM 5220
A ESY RAY MVS ++ELEE I+YK PERR I +W RLQGC+R VE WQ+++M
Sbjct: 1579 AGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREIIRQIWWERLQGCQRIVEDWQKILM 1638
Query: 5221 LRGLVLSPQEMHPLRVKFSSMCRKQGKNSMSRAVLRELLSLPANSDLVRAKAPFDKPLLV 5400
+R LV+SP E +K++S+C K G+ +++ L LL + + L P P +
Sbjct: 1639 VRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHP-LPTVHPQVT 1697
Query: 5401 LALAKQLYQDDHKDEAIRALEDLANHWNKRINPIPKATGRELIPPSTKEPARICAKVLLK 5580
A K +++ K +A + ++ ++ ++ +E ++ A+ LK
Sbjct: 1698 YAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQ----HKQELHKLMARCFLK 1753
Query: 5581 LGEWTELKSKTSNNMQVGELSFVRQQVSPQYRTKESRTPETIAFENTINYYQQATQYDPG 5760
LGEW N+Q ES P+ + YY AT++D
Sbjct: 1754 LGEW-------QLNLQ---------------GINESTIPKVL------QYYSAATEHDRS 1785
Query: 5761 WHKVWHKLASTHFYAVCRERPHPTTVISXXXXXXXXKKMHIXXXXXXXXXXXXXXXXXXX 5940
W+K WH A +F AV + H +I
Sbjct: 1786 WYKAWHAWAVMNFEAVLHYK-HQNQARDEKKKLRHASGANITNATTTATTAASAAAATST 1844
Query: 5941 XXFHSITEPLSVIIDYXXXXXXXXXXXXXXXXAYLSSNSSLPPQHHHVSPLSNDSPSNSA 6120
+S +E SN S P SPL + +
Sbjct: 1845 EGSNSESEA--------------------------ESNESSPTP----SPLQKKVTEDLS 1874
Query: 6121 ENKLYLKHAAHAVRCFAKALMCSPGSRLEDTLRLMQLWFDHGDDKDQDVYFALTETIFDL 6300
K L + AV+ F +++ S G+ L+DTLR++ LWFD+G D V AL E + +
Sbjct: 1875 --KTLLLYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPD--VNEALVEGVKAI 1930
Query: 6301 PVTTWLEAIPQLMARLDCPDDQKSVQLVLRVLCEIARHRPQAVIYALTVASRSKDVHRSK 6480
+ TWL+ IPQL+AR+D P +L+ ++L +I R+ PQA+IY LTVAS+S R
Sbjct: 1931 QIDTWLQVIPQLIARIDTPRPLVG-RLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHN 1989
Query: 6481 NAGTVLEKMMEYHSKLVREASLVTEELVRCAILWHEQWHDALDDASRVYFHRRLQDNNVQ 6660
A +L+ M E+ + LV++A +V+EEL+R AILWHE WH+ L++ASR+YF R NV+
Sbjct: 1990 AANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGER----NVK 2045
Query: 6661 AMFDALRNMNDLMQKGAPTTMKEHSFQQTYSSDLKEAGRYVQAFESSGNVKDLNQAWEIY 6840
MF+ L ++ +M++G P T+KE SF Q Y DL EA + + + SGNVKDL QAW++Y
Sbjct: 2046 GMFEVLEPLHAMMERG-PQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLY 2104
Query: 6841 CSVFKKLRDQLATLNSLDLVYVSPNLVSAKDLELVVPGTYDPSAPIVSIQSFSSKMNVIT 7020
VF+++ QL L SL+L YVSP L+ +DLEL VPGTYDP+ PI+ IQS + + VIT
Sbjct: 2105 YHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVIT 2164
Query: 7021 SKQRPRKMVIRGSNGLDYQFLLKGHEDPRQDERVMQLFGLVNTLLANNSETCRRNLTIQR 7200
SKQRPRK+ + GSNG ++ FLLKGHED RQDERVMQLFGLVNTLLAN+ + R+NL+IQR
Sbjct: 2165 SKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQR 2224
Query: 7201 YSIVALSKDSGLIGWVPNCDTLHTLVKEYREKKAKIPLSIEHKTLQKLSLETEHLTLMQK 7380
Y+++ LS +SGLIGWVP+CDTLH L+++YREKK KI L+IEH+ + +++ + +HLTLMQK
Sbjct: 2225 YAVIPLSTNSGLIGWVPHCDTLHALIRDYREKK-KILLNIEHRIMLRMAPDYDHLTLMQK 2283
Query: 7381 LQLFESALSVTQGEDLRHVLWLKSPSSEVWFDRRTNYTRSVACMSMVGYILGLGDRHPSN 7560
+++FE A++ T G+DL +LWLKSPSSEVWFDRRTNYTRS+A MSMVGYILGLGDRHPSN
Sbjct: 2284 VEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSN 2343
Query: 7561 LMLDRLTGKVVHIDFGDCFEVAMLREKFPERVPFRLTRMLINAMEVTGLDGVYNYTAERV 7740
LMLDRL+GK++HIDFGDCFEVAM REKFPE++PFRLTRML NAMEVTGLDG Y T V
Sbjct: 2344 LMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRTTCHTV 2403
Query: 7741 LKMLRTNQESLLAVLEAFVYDPVINWRLVEGMKKDPK---TRKDTGG------------- 7872
+++LR +++S++AVLEAFVYDP++NWRL++ K K TR D+
Sbjct: 2404 MEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNAKGNKRSRTRTDSYSAGQSVEILDGVEL 2463
Query: 7873 ---RQNMAGAVLPSS----------------STTDSIMETIKRKLDGTEFVHTDGSTPPE 7995
G +P S I+ ++ KL G +F H D
Sbjct: 2464 GEPAHKKTGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDD------ 2517
Query: 7996 PLQVTEQLAMLTEQATSPLNLCQSYIGWCPFW 8091
L V Q+ +L +QATS NLCQ YIGWCPFW
Sbjct: 2518 TLDVPTQVELLIKQATSHENLCQCYIGWCPFW 2549
Score = 445 bits (1144), Expect = e-122
Identities = 336/1187 (28%), Positives = 568/1187 (47%), Gaps = 75/1187 (6%)
Frame = +1
Query: 145 ALASQYRSRITENRDANQRQAARELSRYVRSELKDEPNTFSDAFLNAIDGRTDIASQSAI 324
++ Q+ S + + + +AA+EL YV EL++ S F + ++ I
Sbjct: 20 SVLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEESTRFYDQLNHH--------I 71
Query: 325 YNCMKSNSNIDQKRAGIYLIVCLAETHSGN---VIRYANYLLKMLNNGNGLDEDTVKMAS 495
+ + S+S+ ++++ GI I L GN + R+ANYL +L + D ++MAS
Sbjct: 72 FELV-SSSDANERKGGILAIASLIGVEGGNSTRIGRFANYLRNLLPSS---DPVVMEMAS 127
Query: 496 KALAFLIATCKSYAAELVDRCLDHCHEWLGQNVPHSQQPKNQQEIDQIRRLAASHLSREL 675
KA+ L ++ AE V+ + EWLG + +N+ RR AA + REL
Sbjct: 128 KAIGRLAMAGDTFTAEYVEFEVKRALEWLGAD-------RNEG-----RRHAAVLVLREL 175
Query: 676 ALATPTAFFLRVNLFFKYIFNAVRDKNPAVRIAGIDALHVVLTIVSQREAKN--KTEWFK 849
A++ PT FF +V FF IF AV D A+R + AL L + +QRE K K +W++
Sbjct: 176 AISVPTFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQREPKEMQKPQWYR 235
Query: 850 KCFDEALEGQPNPSQKDDL----DRWHAVALILNELLRISDQRFELIRCE-----SSQFI 1002
F+EA +G K+ DR H LILNEL+RIS E +R E Q +
Sbjct: 236 HTFEEAEKGFDETLAKEKGMNRDDRIHGALLILNELVRISSMEGERLREEMEEITQQQLV 295
Query: 1003 KQKFLKEDEEEGVEWLVLTK-------------------------------------QQT 1071
K+ K+ G + +T + T
Sbjct: 296 HDKYCKDLMGFGTKPRHITPFTSFQAVQPQQSNALVGLLGYSSHQGLMGFGASPSPTKST 355
Query: 1072 IVESVTARKLVLERFPKILDCVRQIIPLANKTSSTKQQSSIYLNTVLMQLLPRICAFPQC 1251
+VES R L+ E+F ++ V K S+K + ++ LLPR+ AF
Sbjct: 356 LVESRCCRDLMEEKFDQVCQWVL-------KCRSSKNS---LIQMTILNLLPRLAAFRPS 405
Query: 1252 DRTFQTISFDTSFTIL------QRNAVAAPAIGMMMLSNPDVHATHIEKTISFISAAI-- 1407
T DT +L + A A+G++ ++ ++ + + I AA+
Sbjct: 406 AFTDTQYLQDTMNHVLSCVKKEKERTAAFQALGLLSVAVRSEFKVYLPRVLDIIRAALPP 465
Query: 1408 -----KKTTNSDVLDNYFTFLFLFVDAYHEQVTTQIKAIIPQLMDITLSRSLANVLKMIM 1572
K+ V FT + + A + IK ++ ++ + LS +L VL +
Sbjct: 466 KDFAHKRQKTVQVDATVFTCISMLARAMGPGIQQDIKELLEPMLAVGLSPALTAVLYDLS 525
Query: 1573 MRIPKLRLNVQDGVMASVYQTLTGSLIPPKSEPIGRPASPKAILQKAET-------DPKE 1731
+IP+L+ ++QDG++ + L +P+ P PK + + + + +
Sbjct: 526 RQIPQLKKDIQDGLLKMLSLVLM-------HKPLRHPGMPKGLAHQLASPGLTTLPEASD 578
Query: 1732 LQRIVLAVDVLGEFYFSRGALQRIMQYVADYYLTADNVEIRLAAVSSCCEMVVPFVGVYK 1911
+ I LA+ LG F F +L + +++ AD++L +++ EIR+ A +C ++ P + +
Sbjct: 579 VASITLALRTLGSFEFEGHSLTQFVRHCADHFLNSEHKEIRMEAARTCSRLLTPSIHLIS 638
Query: 1912 KVTSDKRNSLLQTIYGVLRAVCSVIVNDQDVRVRMQVISCFGQMPRPFLAHLAQPEMLEV 2091
+ +Q + VL + V + D D +R V++ + F AHLAQ E L+
Sbjct: 639 GHAHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDER---FDAHLAQAENLQA 695
Query: 2092 QFMALHDEKLEMQQACVTLLGRLAELNPAXXXXXXXXXXXXXXSQMQQSGQARLEQHSAK 2271
F+AL+D+ E+++ + +GRL+ +NPA ++++ SG R+++ SA+
Sbjct: 696 LFVALNDQVFEIRELAICTVGRLSSMNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSAR 755
Query: 2272 MIAQLAKQSPKFMRPYVGSLMIAMIPKLRNDQKYAE--VTAQVLNAVSEIAVIGGAEIVK 2445
M+ L +P+ +RPY+ ++ A+I KL++ V VL + E+A + G E+ K
Sbjct: 756 MLGHLVSNAPRLIRPYMEPILKALILKLKDPDPDPNPGVINNVLATIGELAQVSGLEMRK 815
Query: 2446 NLKPLFEKLTHMINDSSSLHKREAALRAIGGICRSTAYVVDPYRDYPSLLDDLLRILKTV 2625
+ LF + M+ DSS L KR+ AL +G + ST YVV+PYR YP+LL+ LL LKT
Sbjct: 816 WVDELFVIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTE 875
Query: 2626 MSNTMRREAIKTLGILGAIDPYTHKVFTGSV-QSSTAISTALSLPISETDSKDPRQDIIH 2802
+ RREAI+ LG+LGA+DPY HKV G + QS A + +LS S DS D +
Sbjct: 876 QNQGTRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEM- 934
Query: 2803 WFNYEKCTLEEFYPAITIANLMLMMQDED-SQSYAEIAQAIVTIFRSLGDMAPLYTEQVI 2979
N L+EFYPA+++ LM + +D+ S + + QAI IF+SLG + QV+
Sbjct: 935 LVNMGNLPLDEFYPAVSMVALMRIFRDQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVM 994
Query: 2980 PRLIEVCRRATESSNRANLREFFLQQLANFVAIIRKHAAPYMPAIFTIIADAWKEDISVK 3159
P + V R + +REF QQL V+ ++ H PYM I T++ + W + S++
Sbjct: 995 PTFLNVIRVCDGA-----IREFLFQQLGMLVSFVKSHIRPYMDEIVTLMREFWVMNTSIQ 1049
Query: 3160 MVVIEVLTDMGTAIGNDFSKYTGELIPYLLTVLQTDKTKERVLTVKVMESIQKLTHCIXX 3339
+I ++ + A+G +F Y +LIP++L V D ++ R++++K++ +IQ +
Sbjct: 1050 STIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDNSQGRIVSIKLLAAIQLFGANLDD 1109
Query: 3340 XXXXXXXXXXXXXXXFSLKLSIRNTALSTVLHMTQQVDVSAYAPRMM 3480
+ L R AL TV +T+ +D + YA R++
Sbjct: 1110 YLHLLLPPIVKLFDAPEVPLPSRKAALETVDRLTESLDFTDYASRII 1156
>gi|11136977|emb|CAC15570.1| rapamycin associated protein FRAP2 [Homo
sapiens]
Length = 1188
Score = 940 bits (2429), Expect = 0.0
Identities = 548/1315 (41%), Positives = 754/1315 (56%), Gaps = 39/1315 (2%)
Frame = +1
Query: 4264 EFMDHSEKGPLPISHD----VLGRWAEQTKAFAKACRYKEMSVLKKSGSMQTTFTRKVKL 4431
EFM+HS+KGPLP+ D +LG A + +A+AKA YKE+ K
Sbjct: 1 EFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEFQKGP------------- 47
Query: 4432 EPNDCQSLITYANKLNVQEEAAGVVRYAERNEMNFQMRGRWYEKLNEWEKALGAYELEEK 4611
P +SLI+ NKL E AAGV+ YA ++ +++ WYEKL+EWE AL AY+ +
Sbjct: 48 TPAILESLISINNKLQQPEAAAGVLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKKMD 107
Query: 4612 KKSSCPNLQVYDEKDHLMTPXXXXXXXXXRMHEMRCLEALGRWDELNSKSVVWADQRGNR 4791
P L + MRCLEALG W +L+ + +
Sbjct: 108 TNKDDPELM---------------------LGRMRCLEALGEWGQLHQQCC-------EK 139
Query: 4792 NDSVRDEINKKQLDHKMAVIAARGAWAVDNWERMADYVSVISENTQDGAMLRAVVAVHND 4971
V DE K MA +AA AW + W+ M +Y +I +T DGA RAV+A+H D
Sbjct: 140 WTLVNDETQAK-----MARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQD 194
Query: 4972 ENTKAMGLIEKVREMIDSELTAMANESYERAYIPMVSVQQMAELEEAIEYKTRPERRPRI 5151
+ A I+K R+++D+ELTAMA ESY RAY MVS ++ELEE I+YK PERR I
Sbjct: 195 LFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREII 254
Query: 5152 ALLWSRRLQGCRRNVEQWQRLIMLRGLVLSPQEMHPLRVKFSSMCRKQGKNSMSRAVLRE 5331
+W RLQGC+R VE WQ+++M+R LV+SP E +K++S+C K G+ +++ L
Sbjct: 255 RQIWWERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVL 314
Query: 5332 LLSLPANSDLVRAKAPFDKPLLVLALAKQLYQDDHKDEAIRALEDLANHWNKRINPIPKA 5511
LL + + L P P + A K +++ K +A + ++ ++
Sbjct: 315 LLGVDPSRQLDHP-LPTVHPQVTYAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIAT 373
Query: 5512 TGRELIPPSTKEPARICAKVLLKLGEWTELKSKTSNNMQVGELSFVRQQVSPQYRTKESR 5691
++ +E ++ A+ LKLGEW N+Q ES
Sbjct: 374 EDQQ----HKQELHKLMARCFLKLGEW-------QLNLQ---------------GINEST 407
Query: 5692 TPETIAFENTINYYQQATQYDPGWHKVWHKLASTHFYAVCRERPHPTTVISXXXXXXXXK 5871
P+ + YY AT++D W+K WH A +F AV + H
Sbjct: 408 IPKVL------QYYSAATEHDRSWYKAWHAWAVMNFEAVLHYK-HQNQARDEKKKLRHAS 460
Query: 5872 KMHIXXXXXXXXXXXXXXXXXXXXXFHSITEPLSVIIDYXXXXXXXXXXXXXXXXAYLSS 6051
+I +S +E S +
Sbjct: 461 GANITNATTAATTAATATTTASTEGSNSESEAES------------------------TE 496
Query: 6052 NSSLPPQHHHVSPLSNDSPSNSAENKLYLKHAAHAVRCFAKALMCSPGSRLEDTLRLMQL 6231
NS P SPL + + K L + AV+ F +++ S G+ L+DTLR++ L
Sbjct: 497 NSPTP------SPLQKKVTEDLS--KTLLMYTVPAVQGFFRSISLSRGNNLQDTLRVLTL 548
Query: 6232 WFDHGDDKDQDVYFALTETIFDLPVTTWLEAIPQLMARLDCPDDQKSVQLVLRVLCEIAR 6411
WFD+G D V AL E + + + TWL+ IPQL+AR+D P +L+ ++L +I R
Sbjct: 549 WFDYGHWPD--VNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVG-RLIHQLLTDIGR 605
Query: 6412 HRPQAVIYALTVASRSKDVHRSKNAGTVLEKMMEYHSKLVREASLVTEELVRCAILWHEQ 6591
+ PQA+IY LTVAS+S R A +L+ M E+ + LV++A +V+EEL+R AILWHE
Sbjct: 606 YHPQALIYPLTVASKSTTTARHNAANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEM 665
Query: 6592 WHDALDDASRVYFHRRLQDNNVQAMFDALRNMNDLMQKGAPTTMKEHSFQQTYSSDLKEA 6771
WH+ L++ASR+YF R NV+ MF+ L ++ +M++G P T+KE SF Q Y DL EA
Sbjct: 666 WHEGLEEASRLYFGER----NVKGMFEVLEPLHAMMERG-PQTLKETSFNQAYGRDLMEA 720
Query: 6772 GRYVQAFESSGNVKDLNQAWEIYCSVFKKLRDQLATLNSLDLVYVSPNLVSAKDLELVVP 6951
+ + + SGNVKDL QAW++Y VF+++ QL L SL+L YVSP L+ +DLEL VP
Sbjct: 721 QEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVP 780
Query: 6952 GTYDPSAPIVSIQSFSSKMNVITSKQRPRKMVIRGSNGLDYQFLLKGHEDPRQDERVMQL 7131
GTYDP+ PI+ IQS + + VITSKQRPRK+ + GSNG ++ FLLKGHED RQDERVMQL
Sbjct: 781 GTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQL 840
Query: 7132 FGLVNTLLANNSETCRRNLTIQRYSIVALSKDSGLIGWVPNCDTLHTLVKEYREKKAKIP 7311
FGLVNTLLAN+ + R+NL+IQRY+++ LS +SGLIGWVP+CDTLH L+++YREKK KI
Sbjct: 841 FGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKK-KIL 899
Query: 7312 LSIEHKTLQKLSLETEHLTLMQKLQLFESALSVTQGEDLRHVLWLKSPSSEVWFDRRTNY 7491
L+IEH+ + +++ + +HLTLMQK+++FE A++ T G+DL +LWLKSPSSEVWFDRRTNY
Sbjct: 900 LNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNY 959
Query: 7492 TRSVACMSMVGYILGLGDRHPSNLMLDRLTGKVVHIDFGDCFEVAMLREKFPERVPFRLT 7671
TRS+A MSMVGYILGLGDRHPSNLMLDRL+GK++HIDFGDCFEVAM REKFPE++PFRLT
Sbjct: 960 TRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLT 1019
Query: 7672 RMLINAMEVTGLDGVYNYTAERVLKMLRTNQESLLAVLEAFVYDPVINWRLVEGMKKDPK 7851
RML NAMEVTGLDG Y T V+++LR +++S++AVLEAFVYDP++NWRL++ K K
Sbjct: 1020 RMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNK 1079
Query: 7852 ---TRKDTGG----------------RQNMAGAVLPSS----------------STTDSI 7926
TR D+ G +P S I
Sbjct: 1080 RSRTRTDSYSAGQSVEILDGVELGEPAHKKTGTTVPESIHSFIGDGLVKPEALNKKAIQI 1139
Query: 7927 METIKRKLDGTEFVHTDGSTPPEPLQVTEQLAMLTEQATSPLNLCQSYIGWCPFW 8091
+ ++ KL G +F H D L V Q+ +L +QATS NLCQ YIGWCPFW
Sbjct: 1140 INRVRDKLTGRDFSHDD------TLDVPTQVELLIKQATSHENLCQCYIGWCPFW 1188
>gi|14530309|emb|CAC42395.1| dJ576K7.1 (FK506 binding protein
12-rapamycin associated protein 1) [Homo sapiens]
Length = 895
Score = 704 bits (1816), Expect = 0.0
Identities = 408/1003 (40%), Positives = 575/1003 (56%)
Frame = +1
Query: 4537 QMRGRWYEKLNEWEKALGAYELEEKKKSSCPNLQVYDEKDHLMTPXXXXXXXXXRMHEMR 4716
+++ WYEKL+EWE AL AY+ + P L + MR
Sbjct: 1 EIQATWYEKLHEWEDALVAYDKKMDTNKDDPELM---------------------LGRMR 39
Query: 4717 CLEALGRWDELNSKSVVWADQRGNRNDSVRDEINKKQLDHKMAVIAARGAWAVDNWERMA 4896
CLEALG W +L+ + + V DE K MA +AA AW + W+ M
Sbjct: 40 CLEALGEWGQLHQQCC-------EKWTLVNDETQAK-----MARMAAAAAWGLGQWDSME 87
Query: 4897 DYVSVISENTQDGAMLRAVVAVHNDENTKAMGLIEKVREMIDSELTAMANESYERAYIPM 5076
+Y +I +T DGA RAV+A+H D + A I+K R+++D+ELTAMA ESY RAY M
Sbjct: 88 EYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAM 147
Query: 5077 VSVQQMAELEEAIEYKTRPERRPRIALLWSRRLQGCRRNVEQWQRLIMLRGLVLSPQEMH 5256
VS ++ELEE I+YK PERR I +W RLQGC+R VE WQ+++M+R LV+SP E
Sbjct: 148 VSCHMLSELEEVIQYKLVPERREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSPHEDM 207
Query: 5257 PLRVKFSSMCRKQGKNSMSRAVLRELLSLPANSDLVRAKAPFDKPLLVLALAKQLYQDDH 5436
+K++S+C K G+ +++ L LL + + L P P + A K +++
Sbjct: 208 RTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHP-LPTVHPQVTYAYMKNMWKSAR 266
Query: 5437 KDEAIRALEDLANHWNKRINPIPKATGRELIPPSTKEPARICAKVLLKLGEWTELKSKTS 5616
K +A + ++ ++ ++ +E ++ A+ LKLGEW
Sbjct: 267 KIDAFQHMQHFVQTMQQQAQHAIATEDQQ----HKQELHKLMARCFLKLGEW-------Q 315
Query: 5617 NNMQVGELSFVRQQVSPQYRTKESRTPETIAFENTINYYQQATQYDPGWHKVWHKLASTH 5796
N+Q ES P+ + YY AT++D W+K WH A +
Sbjct: 316 LNLQ---------------GINESTIPKVL------QYYSAATEHDRSWYKAWHAWAVMN 354
Query: 5797 FYAVCRERPHPTTVISXXXXXXXXKKMHIXXXXXXXXXXXXXXXXXXXXXFHSITEPLSV 5976
F AV + H +I +S +E S
Sbjct: 355 FEAVLHYK-HQNQARDEKKKLRHASGANITNATTAATTAATATTTASTEGSNSESEAES- 412
Query: 5977 IIDYXXXXXXXXXXXXXXXXAYLSSNSSLPPQHHHVSPLSNDSPSNSAENKLYLKHAAHA 6156
+ NS P SPL + + K L + A
Sbjct: 413 -----------------------TENSPTP------SPLQKKVTEDLS--KTLLMYTVPA 441
Query: 6157 VRCFAKALMCSPGSRLEDTLRLMQLWFDHGDDKDQDVYFALTETIFDLPVTTWLEAIPQL 6336
V+ F +++ S G+ L+DTLR++ LWFD+G D V AL E + + + TWL+ IPQL
Sbjct: 442 VQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPD--VNEALVEGVKAIQIDTWLQVIPQL 499
Query: 6337 MARLDCPDDQKSVQLVLRVLCEIARHRPQAVIYALTVASRSKDVHRSKNAGTVLEKMMEY 6516
+AR+D P +L+ ++L +I R+ PQA+IY LTVAS+S R A +L+ M E+
Sbjct: 500 IARIDTPRPLVG-RLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKNMCEH 558
Query: 6517 HSKLVREASLVTEELVRCAILWHEQWHDALDDASRVYFHRRLQDNNVQAMFDALRNMNDL 6696
+ LV++A +V+EEL+R AILWHE WH+ L++ASR+YF R NV+ MF+ L ++ +
Sbjct: 559 SNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGER----NVKGMFEVLEPLHAM 614
Query: 6697 MQKGAPTTMKEHSFQQTYSSDLKEAGRYVQAFESSGNVKDLNQAWEIYCSVFKKLRDQLA 6876
M++G P T+KE SF Q Y DL EA + + + SGNVKDL QAW++Y VF+++ QL
Sbjct: 615 MERG-PQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLP 673
Query: 6877 TLNSLDLVYVSPNLVSAKDLELVVPGTYDPSAPIVSIQSFSSKMNVITSKQRPRKMVIRG 7056
L SL+L YVSP L+ +DLEL VPGTYDP+ PI+ IQS + + VITSKQRPRK+ + G
Sbjct: 674 QLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMG 733
Query: 7057 SNGLDYQFLLKGHEDPRQDERVMQLFGLVNTLLANNSETCRRNLTIQRYSIVALSKDSGL 7236
SNG ++ FLLKGHED RQDERVMQLFGLVNTLLAN+ + R+NL+IQRY+++ LS +SGL
Sbjct: 734 SNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGL 793
Query: 7237 IGWVPNCDTLHTLVKEYREKKAKIPLSIEHKTLQKLSLETEHLTLMQKLQLFESALSVTQ 7416
IGWVP+CDTLH L+++YREKK KI L+IEH+ + +++ + +HLTLMQK+++FE A++ T
Sbjct: 794 IGWVPHCDTLHALIRDYREKK-KILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTA 852
Query: 7417 GEDLRHVLWLKSPSSEVWFDRRTNYTRSVACMSMVGYILGLGD 7545
G+DL +LWLKSPSSEVWFDRRTNYTRS+A MSMVGYILGLGD
Sbjct: 853 GDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGD 895
>gi|40888981|gb|AAR97336.1| target of rapamycin [Aedes aegypti]
Length = 2444
Score = 699 bits (1804), Expect = 0.0
Identities = 363/698 (52%), Positives = 490/698 (70%), Gaps = 35/698 (5%)
Frame = +1
Query: 6103 SPSNSAENKLYLKHAAHAVRCFAKALMCSPGSRLEDTLRLMQLWFDHGDDKDQDVYFALT 6282
+P E + ++A AV F +++ S G+ L+DTLRL+ LWFD+G + VY AL
Sbjct: 1765 NPGGDKEKCMIRQYAVPAVEGFFRSINLSHGNSLQDTLRLLTLWFDYG--QYPKVYEALV 1822
Query: 6283 ETIFDLPVTTWLEAIPQLMARLDCPDDQKSVQLVLRVLCEIARHRPQAVIYALTVASRSK 6462
E + + + TWL+ IPQL+AR+D P + QL+ ++L +I + PQA++Y LTVAS S
Sbjct: 1823 EGMRVIEINTWLQVIPQLIARIDTPRNLVG-QLIHQLLNDIGKCHPQALVYPLTVASNSA 1881
Query: 6463 DVHRSKNAGTVLEKMMEYHSKLVREASLVTEELVRCAILWHEQWHDALDDASRVYFHRRL 6642
R + A +L M E+ S LV +A + +EEL+R ILWHEQWH+ L++ASR+YF
Sbjct: 1882 SSARRQAAHKILGSMGEHSSNLVNQAIMCSEELIRVTILWHEQWHEGLEEASRLYFG--- 1938
Query: 6643 QDNNVQAMFDALRNMNDLMQKGAPTTMKEHSFQQTYSSDLKEAGRYVQAFESSGNVKDLN 6822
D N++ MF+ L ++ ++Q+G P T+KE SF Q Y DL EA + + +++SGN++DLN
Sbjct: 1939 -DRNIKGMFETLEPLHQMLQRG-PQTLKETSFNQAYGRDLNEAQEWCKHYKNSGNIRDLN 1996
Query: 6823 QAWEIYCSVFKKLRDQLATLNSLDLVYVSPNLVSAKDLELVVPGTYDPSAPIVSIQSFSS 7002
QAW++Y VF+++ QL L SL+L YVSP L++ +DLEL VPG+Y P ++ I S S
Sbjct: 1997 QAWDLYYHVFRRISRQLPQLTSLELQYVSPKLLACRDLELAVPGSYAPGQELIRIASIQS 2056
Query: 7003 KMNVITSKQRPRKMVIRGSNGLDYQFLLKGHEDPRQDERVMQLFGLVNTLLANNSETCRR 7182
+ VITSKQRPRK+ IRGSNG +Y FLLKGHED RQDERVMQLFGLVNTLL N+ +T RR
Sbjct: 2057 NLQVITSKQRPRKLCIRGSNGKEYMFLLKGHEDLRQDERVMQLFGLVNTLLLNDPDTFRR 2116
Query: 7183 NLTIQRYSIVALSKDSGLIGWVPNCDTLHTLVKEYREKKAKIPLSIEHKTLQKLSLETEH 7362
NLTIQRY+ + LS +SGLIGWVP+CDTLHTL ++YREKK K L+IEH+ + +++ + +H
Sbjct: 2117 NLTIQRYAFIPLSTNSGLIGWVPHCDTLHTLTRDYREKK-KTMLNIEHRIMLRMATDYDH 2175
Query: 7363 LTLMQKLQLFESALSVTQGEDLRHVLWLKSPSSEVWFDRRTNYTRSVACMSMVGYILGLG 7542
LTLMQK+++FE AL +T+G+DL +LWLKSPSSEVWFDRRTNYTRS+A MSMVGYILGLG
Sbjct: 2176 LTLMQKVEVFEYALELTKGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLG 2235
Query: 7543 DRHPSNLMLDRLTGKVVHIDFGDCFEVAMLREKFPERVPFRLTRMLINAMEVTGLDGVYN 7722
DRHPSNLMLDRL+GK++HIDFGDCFEVAM REKFPE++PFRLTRMLINAMEVTG++G Y
Sbjct: 2236 DRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLINAMEVTGIEGTYR 2295
Query: 7723 YTAERVLKMLRTNQESLLAVLEAFVYDPVINWRLVEGMKKDPKTRKDTG----------- 7869
T E V+ +LR N++SL+AVLEAFVYDP++NWRL++ + K+ +++ T
Sbjct: 2296 RTCESVMHVLRRNKDSLMAVLEAFVYDPLLNWRLLD-VDKNRRSKNATDVDSTTESMEET 2354
Query: 7870 ------------GRQNMAGAVL---------PSSSTTD---SIMETIKRKLDGTEFVHTD 7977
N G V+ P+ +T + +I++ +K+KL G +F
Sbjct: 2355 LDLLINARNLRMNEANGGGDVVDQGSNCIANPAEATNNKARAIVDRVKQKLTGKDF---- 2410
Query: 7978 GSTPPEPLQVTEQLAMLTEQATSPLNLCQSYIGWCPFW 8091
EP+Q Q+ +L QAT+ NLCQ YIGWCPFW
Sbjct: 2411 --NTVEPVQ--RQIDLLIRQATNNENLCQCYIGWCPFW 2444
Score = 381 bits (979), Expect = e-103
Identities = 311/1161 (26%), Positives = 542/1161 (45%), Gaps = 59/1161 (5%)
Frame = +1
Query: 175 TENRDANQRQAARELSRYVRSELKDEPNTFSDAFLNAIDGRTDIASQSAIYNCMKSNSNI 354
+ N+DA Q +AA+ELS YV++EL++ P AF + I+ M S+++I
Sbjct: 14 SRNKDA-QNKAAQELSLYVKTELREIPQDDLLAFFEDFN--------QYIFE-MLSSADI 63
Query: 355 DQKRAGIYLIVCLAETHSGNVIRYANYLLKMLNNGNGL----DEDTVKMASKALAFLIAT 522
+ K+ G+ I CL SG+V+ + + NN L D +++A+K L L
Sbjct: 64 NDKKGGVLAINCLI---SGDVVNTTTQISRYSNNLRNLLPSSDISVMELAAKVLVKLALL 120
Query: 523 CKSYAAELVDRCLDHCHEWLGQNVPHSQQPKNQQEIDQIRRLAASHLSRELALATPTAFF 702
S AE + + EWL +E + +R AA + RELA+A PT F+
Sbjct: 121 PGSKGAESFEFDIKRAFEWL------------MEERTEGKRHAAVLVLRELAVAMPTFFY 168
Query: 703 LRVNLFFKYIFNAVRDKNPAVRIAGIDALHVVLTIVSQREA---KNKTEWFKKCFDEA-- 867
+V FF++IF A++D P +R AL VL + SQRE N +W+ +
Sbjct: 169 QQVGSFFEHIFVAIKDPKPMIREGAGQALRAVLIVTSQREGTKQNNNPQWYNHLLRQRNG 228
Query: 868 -LEG---QPNPSQKDDLDRWHAVALILNELLRISDQRFE--LIRCESSQFIKQKFLKEDE 1029
L+G + +DD R H ++ NE+LR S+ +E ++ ES + ++ DE
Sbjct: 229 MLQGASFREKGFNRDD--RIHGAIIVFNEILRCSNAAWEKKYMQLESLN-VDRRSRHTDE 285
Query: 1030 ---------------------------EEGVEWLVLTKQQTIVESVTARKLVLERFPKIL 1128
EG + + +I ES R L + + I
Sbjct: 286 GHSIFPRIRVPFMDKLGGGHSSGASRTSEGSDVKFFRQNSSIQESAICRALTNDNYELI- 344
Query: 1129 DCVRQIIPLANKTSSTKQQSSIYLNTVLMQLLPRICAFPQCDRTFQTISFDTSFTIL--- 1299
K + S Y+ L+ +LPR+ AF + D + ++ IL
Sbjct: 345 ---------CQKVLEQRNSKSPYVIQSLLTILPRLAAFNRRDFVNNHLKTVVNYLILTIK 395
Query: 1300 ----QRNAVAAPAIGMMMLSNPDVHATHIEKTISFISAAI--KKTTNSD---VLDNYFTF 1452
+RN +A +G + ++ A + I I+AA+ K+T + V + F
Sbjct: 396 SKEKERN-LAFVTLGYIAVAVEKDIAPFRTRIIEVITAALPPKETPSKKKVCVDPSVFMC 454
Query: 1453 LFLFVDAYHEQVTTQIKAIIPQLMDITLSRSLANVLKMIMMRIPKLRLNVQDGVMASVYQ 1632
+ L A +TT +K++I ++ LS L L + +P+LR + G++
Sbjct: 455 ITLLGHALKSAITTDVKSLILPMLSTGLSTGLTVCLHELSENVPQLRQEITSGLLK---- 510
Query: 1633 TLTGSLIPPKSEPIGRPASPKAILQKA--ETDPKELQRIVLAVDVLGEFYFSRGALQRIM 1806
+ ++ K P P P+ + + E ++ VLA+ LG F F +L +
Sbjct: 511 -ILSCVLMNKPLPQFIPGRPQGGMNTSLYEQQIQDTPTTVLALRTLGTFNFEGHSLLPFV 569
Query: 1807 QYVADYYLTADNVEIRLAAVSSCCEMVVPFVGVYKKVTSDKRNSLLQTIYGVLRAVCSVI 1986
Q AD++L ++ EIR+ AV +C ++ + + ++D +L QT+ VL + V
Sbjct: 570 QRCADHFLLSEQQEIRIEAVQTCTLLLK--LALQSVDSADGSETLTQTVGSVLEKILIVG 627
Query: 1987 VNDQDVRVRMQVISCFGQMPRPFLAHLAQPEMLEVQFMALHDEKLEMQQACVTLLGRLAE 2166
+ D D VR++V+ + F + LAQP L + ++DE E+++ + ++GRL+
Sbjct: 628 ITDVDPNVRLRVLK---SLDDSFDSQLAQPWFLSSLLITMNDEVFEIRELAIIIIGRLSA 684
Query: 2167 LNPAXXXXXXXXXXXXXXSQMQQSGQARLEQHSAKMIAQLAKQSPKFMRPYVGSLMIAMI 2346
+NPA ++++ SG +R ++ SA+M+ L +P+ + Y+ ++ ++
Sbjct: 685 INPAYVMPSLRKTMVQILTELEHSGMSRNKEQSARMLDHLIVSTPRLISSYMRPILSILV 744
Query: 2347 PKLRNDQKYAEVTAQVLNAVSEIAVIGGAEIV--KNLKPLFEKLTHMINDSSSLHKREAA 2520
PKL+ + V VL A+ ++A + G V K L L M++D+ S KR A
Sbjct: 745 PKLKEPESNPGVVLNVLRAIGDLAEVNGGHNVLEKWSDELLATLLEMLSDAGSTEKRGVA 804
Query: 2521 LRAIGGICRSTAYVVDPYRDYPSLLDDLLRILKTVMSNTMRREAIKTLGILGAIDPYTHK 2700
L +G + +T V PY YP+L+D L+ LKT +RRE I+ LG+LGA+DPY HK
Sbjct: 805 LWTLGQLVSATGQAVKPYHKYPNLIDILINFLKTEQQPYVRRETIRVLGLLGALDPYKHK 864
Query: 2701 VFTGSVQSSTAISTALSLPISETDSKDPRQDIIHWFNYEKCTLEEFYPAITIANLMLMMQ 2880
+ G + S T + +S+ S+T+ N LEE+YPA+ I+ LM +++
Sbjct: 865 MNRGLIDSQTN-NILISISDSKTEEYTDLSTSEMLINMNN-QLEEYYPAVAISTLMKILR 922
Query: 2881 DED-SQSYAEIAQAIVTIFRSLGDMAPLYTEQVIPRLIEVCRRATESSNRANLREFFLQQ 3057
D S + + QAI IF+SLG Y QV+P L+ R A NL+EF QQ
Sbjct: 923 DPTLSSHHTSVVQAITFIFKSLGIKCVPYLSQVLPSLLGNIRNA-----EMNLKEFLFQQ 977
Query: 3058 LANFVAIIRKHAAPYMPAIFTIIADAWKEDISVKMVVIEVLTDMGTAIGNDFSKYTGELI 3237
L+ + I+++H +M IF +I W ++ +I ++ + A+G +F Y +L+
Sbjct: 978 LSILIEIVKQHIISFMEEIFQLIKTFWNSIYPLQPTLIILVEKIAIALGCEFKIYLPQLM 1037
Query: 3238 PYLLTVLQTDKTKERVLTVKVMESIQKLTHCIXXXXXXXXXXXXXXXXXFSLKLSIRNTA 3417
P +L VL D + R++TVK++ ++QK + + + + A
Sbjct: 1038 PQILRVLLHDASTHRIVTVKLLNALQKFGNNLDDYLHLIIPAIVKLFEPIEVPYQVSLAA 1097
Query: 3418 LSTVLHMTQQVDVSAYAPRMM 3480
L T+ ++ + +D + ++ R++
Sbjct: 1098 LETINYLAEILDFTDFSSRII 1118
Score = 322 bits (824), Expect = 1e-85
Identities = 214/631 (33%), Positives = 313/631 (48%), Gaps = 6/631 (0%)
Frame = +1
Query: 3946 ITKQRLNKDALMPQWKNENLTSKDEWLQWLMKIRIGFLTYGSSPSLRAASSLGDQHPHLA 4125
I K ++ L +K S+D+WL+WL ++ IG L SP+LR+ +L +P L
Sbjct: 1211 IRKLNVSTADLQLAFKANRRVSRDDWLEWLRRLSIGLLKESKSPALRSCRTLAQNYPQLL 1270
Query: 4126 RDLFPAAFMSVWTELDSDVQNDLTSCLLRAIST-GIPELIQTILNLAEFMDHSEKGPLPI 4302
+DLF AAF+S WT+L ++ +L+S L +A+ +PE+ QTILNLAEFM+H E L I
Sbjct: 1271 KDLFNAAFVSCWTDLPDSLKEELSSSLRQALMVPDLPEITQTILNLAEFMEHCENDALRI 1330
Query: 4303 SHDVLGRWAEQTKAFAKACRYKEMSVLKKSGSMQTTFTRKVKLEPNDCQSLITYANKLNV 4482
+LG A + +A+AKA YKE L Q+ F +SLI NKL
Sbjct: 1331 DPKILGERAMECRAYAKALHYKEEEFLNMKDKDQSVF-----------ESLILINNKLQQ 1379
Query: 4483 QEEAAGVVRYAERN-----EMNFQMRGRWYEKLNEWEKALGAYELEEKKKSSCPNLQVYD 4647
+E A G++ YA + EM Q+R WYEKL+ WEKAL Y+ +K +S+ +L
Sbjct: 1380 KEAAEGLLEYAMEHRSASEEMKVQVR--WYEKLHSWEKALNLYQ--DKLESNPGDLD--- 1432
Query: 4648 EKDHLMTPXXXXXXXXXRMHEMRCLEALGRWDELNSKSVVWADQRGNRNDSVRDEINKKQ 4827
R+ + RCLEALG W LN+ + + G S
Sbjct: 1433 ----------------SRLGQWRCLEALGEWSTLNTLTKETWESLGTEGQS--------- 1467
Query: 4828 LDHKMAVIAARGAWAVDNWERMADYVSVISENTQDGAMLRAVVAVHNDENTKAMGLIEKV 5007
K +AA AW + +WE M ++V I E+TQDG+ RAV+AVH+ E A LI+
Sbjct: 1468 ---KAGRLAAAAAWGLKDWEGMQEFVKFIPEDTQDGSFYRAVLAVHHGEYELAQTLIDDT 1524
Query: 5008 REMIDSELTAMANESYERAYIPMVSVQQMAELEEAIEYKTRPERRPRIALLWSRRLQGCR 5187
R+++D+ELTAMA ESYERAY MV VQ ++ELEE I+YK PER+ I +W RL G +
Sbjct: 1525 RDLLDTELTAMAGESYERAYGAMVCVQMLSELEEVIQYKLIPERQETIKAMWWDRLLGGQ 1584
Query: 5188 RNVEQWQRLIMLRGLVLSPQEMHPLRVKFSSMCRKQGKNSMSRAVLRELLSLPANSDLVR 5367
R VE WQR++ + LV+ P +KF+S+CRK +S L LL S+
Sbjct: 1585 RLVEDWQRILQVHTLVVHPANDVKTWLKFASLCRKSDSLKLSEKTLVMLLRYNP-SEYPD 1643
Query: 5368 AKAPFDKPLLVLALAKQLYQDDHKDEAIRALEDLANHWNKRINPIPKATGRELIPPSTKE 5547
F +P + A AK L+ +++A L L N E
Sbjct: 1644 HPLEFMQPDISFAYAKHLWAAGEQEKAYNQLNRLVADMGIEGN---------FDVEEKDE 1694
Query: 5548 PARICAKVLLKLGEWTELKSKTSNNMQVGELSFVRQQVSPQYRTKESRTPETIAFENTIN 5727
R+ A+ +KLG+W +L + +Q + + +
Sbjct: 1695 NRRLLARCYMKLGQWQ------------NQLQGLNEQ----------------SIKGILA 1726
Query: 5728 YYQQATQYDPGWHKVWHKLASTHFYAVCRER 5820
Y++AT++D W+K WH A +F V ++
Sbjct: 1727 CYEKATKHDSNWYKAWHLWAYMNFEVVQNQK 1757
>gi|17864562|ref|NP_524891.1| CG5092-PA [Drosophila melanogaster]
gi|7297995|gb|AAF53237.1| CG5092-PA [Drosophila melanogaster]
Length = 2470
Score = 698 bits (1801), Expect = 0.0
Identities = 552/1957 (28%), Positives = 896/1957 (45%), Gaps = 80/1957 (4%)
Frame = +1
Query: 178 ENRDAN-QRQAARELSRYVRSELKDEPNTFSDAFLNAIDGRTDIASQSAIYNCMKSNSNI 354
++R+ N Q +A ++L YV++EL++ F + D I+ M + ++I
Sbjct: 15 KSRNRNVQNKATQDLLFYVKTELREMSQEELAQFFDEFDHH--------IFT-MVNATDI 65
Query: 355 DQKRAGIYLIVCLAETHSGNVIR-----YANYLLKMLNNGNGLDEDTVKMASKALAFLIA 519
++K+ G + CL R Y N L +L D +++A+++L L
Sbjct: 66 NEKKGGALAMKCLINCEGSLTARKGISPYLNRLRDLLLIN---DVSVMEIAARSLVKLAN 122
Query: 520 TCKSYAAELVDRCLDHCHEWLGQNVPHSQQPKNQQEIDQIRRLAASHLSRELALATPTAF 699
S A+ D + E L + E + RR +A + RELA+A PT F
Sbjct: 123 MPTSKGADSFDFDIKKAFEVL------------RGERQEYRRHSAVFILRELAIALPTYF 170
Query: 700 FLRVNLFFKYIFNAVRDKNPAVRIAGIDALHVVLTIVSQREAKNKT---EWFKKCFDEAL 870
+ + FF+ IFNA+ D PA+R + +AL L + +QRE+ ++ +W++ C+DEA
Sbjct: 171 YQHILTFFEVIFNAIFDPKPAIRESAGEALRAALIVTAQRESTKQSSEPQWYRICYDEA- 229
Query: 871 EGQPNP---SQKDDL-----DRWHAVALILNELLRIS----DQRFELIRCESSQFIKQKF 1014
G N S KD DR H ++ NEL R + ++R+ ++ + KF
Sbjct: 230 NGSFNADLGSSKDQKGVTRDDRIHGGLVVFNELFRCANATWERRYTSLKTLFPKTQHNKF 289
Query: 1015 LKED--------------------------------EEEGVEWLVLTKQQTIVESVTARK 1098
L+ E E + + ++ES A++
Sbjct: 290 LEASSSSSMGSQLNTLVPRLKVPFIDKLGSTQTHLGEGEHHKGVAKFASHNVLESAYAQE 349
Query: 1099 LVLERFPKILDCVRQIIPLANKTSSTKQQSSIYLNTVLMQLLPRICAFPQCDRTFQTISF 1278
++ E + I D V L +TS S Y+ L+Q+LPR+ AF + F
Sbjct: 350 ILQEHYTSICDNV-----LEQRTSK-----SPYVQQALLQILPRLAAFNRA--VFVEKYL 397
Query: 1279 DTSFTILQR--------NAVAAPAIGMMMLSNPDVHATHIEKTISFISAAI--KKTTNS- 1425
T + L + VA IG M ++ H+ ++ + A+ K T+
Sbjct: 398 QTCVSHLMQILRGKEKDRTVAYITIGYMAVAVQSAIEVHLSSIMTSVKVALPSKDLTSKR 457
Query: 1426 --DVLDNYFTFLFLFVDAYHEQVTTQIKAIIPQLMDITLSRSLANVLKMIMMRIPKLRLN 1599
V F + L A ++ +K I+ Q+ LS +L L+ + +P+L+
Sbjct: 458 KVPVDPAVFACITLLAHAVKSEIADDVKDILEQMFYTGLSPALTVCLRELSENVPQLKSA 517
Query: 1600 VQDGVMASVYQTLTGSLIPPKSEPIGRPASPKAILQKAETDPKELQRIVLAVDVLGEFYF 1779
+ +G++ + Q L K+ + A P + + + VLA+ LG F F
Sbjct: 518 ITEGLIGILSQVLMN-----KAAILPYTALPTIAIDGSLMQNGDGATTVLALKTLGTFNF 572
Query: 1780 SRGALQRIMQYVADYYLTADNVEIRLAAVSSCCEMVVPFVGVYKKVTSDKRNSLLQTIYG 1959
+ +Q ADY++ + EIRL AV +C ++ + V + + +L T+
Sbjct: 573 EEQNMLDFVQRCADYFIVHEQQEIRLEAVQTCTRLLK--LAVQSSESMENSKTLSDTVSH 630
Query: 1960 VLRAVCSVIVNDQDVRVRMQVISCFGQMPRPFLAHLAQPEMLEVQFMALHDEKLEMQQAC 2139
V+ + V + D D VR++++ + F LAQPE L F+ LHDE E+++
Sbjct: 631 VIERLLMVAITDMDCNVRIRILR---SLDETFDGKLAQPESLNSLFITLHDEIFEIRELA 687
Query: 2140 VTLLGRLAELNPAXXXXXXXXXXXXXXSQMQQSGQARLEQHSAKMIAQLAKQSPKFMRPY 2319
+ +GRL+ +NPA + ++ SG +R ++ SAKM+ L +P+ + Y
Sbjct: 688 MVTIGRLSSINPAYVMPKLRTTMIELITDLKYSGMSRNKEQSAKMLDHLVISTPRLISSY 747
Query: 2320 VGSLMIAMIPKLRNDQKYAEVTAQVLNAVSEIAVIGGAEIVKNL--KPLFEKLTHMINDS 2493
+ ++ A++PKL + V VL + ++A + G L L L M+ D+
Sbjct: 748 MNPILKALVPKLHEPESNPGVILNVLRTIGDLAEVNGGSDEMELWADDLLSILLEMLGDA 807
Query: 2494 SSLHKREAALRAIGGICRSTAYVVDPYRDYPSLLDDLLRILKTVMSNTMRREAIKTLGIL 2673
S KR AL +G + +T VV PY YP L+D L+ LKT ++RRE I+ LG+L
Sbjct: 808 GSPDKRGVALWTLGQLISATGRVVTPYHKYPVLIDILINFLKTEQRRSIRRETIRVLGLL 867
Query: 2674 GAIDPYTHKVFTGSVQSSTAISTALSLPISETDSK-DPRQDI------IHWFNYEKCTLE 2832
GA+DPY HK+ G + S ++ I+ +D K D QDI ++ N L+
Sbjct: 868 GAMDPYKHKMNKGLIDSQKD-----NVLIAYSDGKVDESQDISTAELLVNMGN----ALD 918
Query: 2833 EFYPAITIANLMLMMQDED-SQSYAEIAQAIVTIFRSLGDMAPLYTEQVIPRLIEVCRRA 3009
E+YPA+ IA LM +++D S + + QA+ IF+SLG Y QV+P L++ R A
Sbjct: 919 EYYPAVAIAALMRILRDPTLSTRHTSVVQAVTFIFQSLGIKCVPYLAQVLPNLLDNVRTA 978
Query: 3010 TESSNRANLREFFLQQLANFVAIIRKHAAPYMPAIFTIIADAWKEDISVKMVVIEVLTDM 3189
NLREF QQLA VA ++ H YM IF +I + W + ++ +I ++ +
Sbjct: 979 DN-----NLREFLFQQLAILVAFVKLHIISYMGDIFKLIKEFWTINTPLQNTLINLIEQI 1033
Query: 3190 GTAIGNDFSKYTGELIPYLLTVLQTDKTKERVLTVKVMESIQKLTHCIXXXXXXXXXXXX 3369
A+G +F Y ELIP +L VLQ D +K+R++T ++++++QK +
Sbjct: 1034 AVALGCEFRDYLAELIPQILRVLQHDNSKDRMVTRRLLQALQKFGSTLGYYLPLILPPIV 1093
Query: 3370 XXXXXFSLKLSIRNTALSTVLHMTQQVDVSAYAPRMMQSWHHNI-STAEMRDXXXXXXXX 3546
+ + AL T+ ++ Q+D + ++ R++ + + E+RD
Sbjct: 1094 KLFDSPYVPQQVSMVALETINNLACQLDFTDFSSRIIHPLVRVLDAEPELRDQAMTTLRS 1153
Query: 3547 XXXXXXXFFDIFKRGVDQKLRDYNLDKSVHYEQYRKLAQRAQMSRDVLTSSVFAGSNGNI 3726
+ +F V + L + + + E K + + S A S G
Sbjct: 1154 LAKQLGKKYLVFVPMVQRTLNKHRIVDPEYEELLSK----------IKSCSTLADSYG-- 1201
Query: 3727 QYSSTQAGMRGQANNVYANNDLHERLMNGSIDSGASRQDNRDDYYRYGVEEKKEVPKVAP 3906
AG + + NN+ P
Sbjct: 1202 ------AGESELRPSRFKNNE--------------------------------------P 1217
Query: 3907 TTARPTSELVTVQITKQRLNKDALMPQWKNENLTSKDEWLQWLMKIRIGFLTYGSSPSLR 4086
S +Q+T L W+ SKD+W++WL ++ IG L S +LR
Sbjct: 1218 FVTDRNSNNKNLQVTTNELR-----TAWQVTRRVSKDDWVEWLKRLSIGLLKESPSHALR 1272
Query: 4087 AASSLGDQHPHLARDLFPAAFMSVWTELDSDVQNDLTSCLLRAIS-TGIPELIQTILNLA 4263
A SL ++ L RDLF AAF+S WTEL D++N+LT L++A+ T +PE+ QTILNLA
Sbjct: 1273 ACRSLAQEYDTLLRDLFNAAFISCWTELSPDLKNELTQSLIQALQVTDMPEITQTILNLA 1332
Query: 4264 EFMDHSEKGPLPISHDVLGRWAEQTKAFAKACRYKEMSVLKKSGSMQTTFTRKVKLEPND 4443
EFM+H ++ P+PI +LG A +A+AKA RYKE L + S
Sbjct: 1333 EFMEHCDRDPIPIETKLLGTRAMACRAYAKALRYKEEEFLLREDSQV------------- 1379
Query: 4444 CQSLITYANKLNVQEEAAGVV-RYAE-RNEMNFQMRGRWYEKLNEWEKALGAYELEEKKK 4617
+SLI NKL +E A G++ RY NE+N Q GRWYEKL+ W++AL YE K
Sbjct: 1380 FESLILINNKLQQREAAEGLLTRYRNAANELNVQ--GRWYEKLHNWDEALEHYERNLKTD 1437
Query: 4618 SSCPNLQVYDEKDHLMTPXXXXXXXXXRMHEMRCLEALGRWDELNSKSVVWADQRGNRND 4797
SS R+ MRCLEALG W EL++ + + G
Sbjct: 1438 SS---------------------DLEARLGHMRCLEALGDWSELSNVTKHEWENFGTEAK 1476
Query: 4798 SVRDEINKKQLDHKMAVIAARGAWAVDNWERMADYVSVISENTQDGAMLRAVVAVHNDEN 4977
S + +AA AW + +WE M +YV I E+TQDG+ RAV+AVH+D+
Sbjct: 1477 S------------RAGPLAAVAAWGLQDWEAMREYVRCIPEDTQDGSYYRAVLAVHHDDF 1524
Query: 4978 TKAMGLIEKVREMIDSELTAMANESYERAYIPMVSVQQMAELEEAIEYKTRPERRPRIAL 5157
A LI++ R+++D+ELT+MA ESYERAY MV VQ +AELEE I+YK PERR +
Sbjct: 1525 ETAQRLIDETRDLLDTELTSMAGESYERAYGAMVCVQMLAELEEVIQYKLIPERREPLKT 1584
Query: 5158 LWSRRLQGCRRNVEQWQRLIMLRGLVLSPQEMHPLRVKFSSMCRKQGKNSMSRAVLRELL 5337
+W +RLQG +R VE W+R+I + LV+ P E +K++S+CRK G +S L LL
Sbjct: 1585 MWWKRLQGGQRLVEDWRRIIQVHSLVVKPHEDIHTWLKYASLCRKSGSLHLSHKTLVMLL 1644
Query: 5338 SLPANSDLVRAKAPFDKPLLVLALAKQLYQDDHKDEAIRALEDLANHWNKRINPIPKATG 5517
+ P ++P + A K + ++ EA L + +++ ++ +P
Sbjct: 1645 GTDPKLN-PNQPLPCNQPQVTYAYTKYMAANNQLQEAYEQLTHFVSTYSQELSCLPPEAL 1703
Query: 5518 RELIPPSTKEPARICAKVLLKLGEWTELKSKTSNNMQVGELSFVRQQVSPQYRTKESRTP 5697
++ + R+ A+ L++ W Q + ++S P
Sbjct: 1704 KQ-------QDQRLMARCYLRMATW-------------------------QNKLQDSIRP 1731
Query: 5698 ETIAFENTINYYQQATQYDPGWHKVWHKLASTHFYAV 5808
+ A + + +++AT YDP W+K WH A +F V
Sbjct: 1732 D--AIQGALECFEKATSYDPNWYKAWHLWAYMNFKVV 1766
Score = 677 bits (1747), Expect = 0.0
Identities = 350/686 (51%), Positives = 483/686 (70%), Gaps = 35/686 (5%)
Frame = +1
Query: 6139 KHAAHAVRCFAKALMCSPGSRLEDTLRLMQLWFDHGDDKDQDVYFALTETIFDLPVTTWL 6318
++A AV+ F +++ G+ L+DTLRL+ LWFD+G+ + VY AL + + + TWL
Sbjct: 1800 RYAVPAVQGFFRSISLIKGNSLQDTLRLLTLWFDYGNHAE--VYEALLSGMKLIEINTWL 1857
Query: 6319 EAIPQLMARLDCPDDQKSVQLVLRVLCEIARHRPQAVIYALTVASRSKDVHRSKNAGTVL 6498
+ IPQL+AR+D Q QL+ ++L +I ++ PQA++Y LTVAS+S + R A +L
Sbjct: 1858 QVIPQLIARIDT-HRQLVGQLIHQLLMDIGKNHPQALVYPLTVASKSASLARRNAAFKIL 1916
Query: 6499 EKMMEYHSKLVREASLVTEELVRCAILWHEQWHDALDDASRVYFHRRLQDNNVQAMFDAL 6678
+ M ++ LV +A + +EEL+R AILWHEQWH+ L++ASR+YF D NV+ MF+ L
Sbjct: 1917 DSMRKHSPTLVEQAVMCSEELIRVAILWHEQWHEGLEEASRLYFG----DRNVKGMFEIL 1972
Query: 6679 RNMNDLMQKGAPTTMKEHSFQQTYSSDLKEAGRYVQAFESSGNVKDLNQAWEIYCSVFKK 6858
++ ++++G P T+KE SF Q Y +L EA + Q +++S V DL++AW+IY VF+K
Sbjct: 1973 EPLHAMLERG-PQTLKETSFSQAYGRELTEAYEWSQRYKTSAVVMDLDRAWDIYYHVFQK 2031
Query: 6859 LRDQLATLNSLDLVYVSPNLVSAKDLELVVPGTYDPSAPIVSIQSFSSKMNVITSKQRPR 7038
+ QL L SL+L YVSP L++ KDLEL VPG+Y+P ++ I + + VITSKQRPR
Sbjct: 2032 ISRQLPQLTSLELPYVSPKLMTCKDLELAVPGSYNPGQELIRISIIKTNLQVITSKQRPR 2091
Query: 7039 KMVIRGSNGLDYQFLLKGHEDPRQDERVMQLFGLVNTLLANNSETCRRNLTIQRYSIVAL 7218
K+ IRGSNG DY +LLKGHED RQDERVMQLF LVNTLL ++ +T RRNL IQRY+++ L
Sbjct: 2092 KLCIRGSNGKDYMYLLKGHEDLRQDERVMQLFSLVNTLLLDDPDTFRRNLAIQRYAVIPL 2151
Query: 7219 SKDSGLIGWVPNCDTLHTLVKEYREKKAKIPLSIEHKTLQKLSLETEHLTLMQKLQLFES 7398
S +SGLIGWVP+CDTLHTL+++YR+KK K+PL+ EH+T+ + + +HLTLMQK+++FE
Sbjct: 2152 STNSGLIGWVPHCDTLHTLIRDYRDKK-KVPLNQEHRTMLNFAPDYDHLTLMQKVEVFEH 2210
Query: 7399 ALSVTQGEDLRHVLWLKSPSSEVWFDRRTNYTRSVACMSMVGYILGLGDRHPSNLMLDRL 7578
AL TQG+DL +LWLKSPSSE+WF+RR NYTRS+A MSMVGYILGLGDRHPSNLMLDR+
Sbjct: 2211 ALGQTQGDDLAKLLWLKSPSSELWFERRNNYTRSLAVMSMVGYILGLGDRHPSNLMLDRM 2270
Query: 7579 TGKVVHIDFGDCFEVAMLREKFPERVPFRLTRMLINAMEVTGLDGVYNYTAERVLKMLRT 7758
+GK++HIDFGDCFEVAM REKFPE++PFRLTRMLI AMEVTG++G Y T E V+ +LR
Sbjct: 2271 SGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLIKAMEVTGIEGTYRRTCESVMLVLRR 2330
Query: 7759 NQESLLAVLEAFVYDPVINWRLVEGMKKD---------PKTRKDTGGRQNMAGAV---LP 7902
N++SL+AVLEAFVYDP++NWRL++ KK P R +G + +++ +V LP
Sbjct: 2331 NKDSLMAVLEAFVYDPLLNWRLLDVDKKGNDAVAGAGAPGGRGGSGMQDSLSNSVEDSLP 2390
Query: 7903 -----------------------SSSTTDSIMETIKRKLDGTEFVHTDGSTPPEPLQVTE 8013
++S +++ +K KL GT+F T+ S +
Sbjct: 2391 MAKSKPYDPTLQQGGLHNNVADETNSKASQVIKRVKCKLTGTDF-QTEKSVNEQ-----S 2444
Query: 8014 QLAMLTEQATSPLNLCQSYIGWCPFW 8091
Q+ +L +QAT+ NLCQ YIGWCPFW
Sbjct: 2445 QVELLIQQATNNENLCQCYIGWCPFW 2470
>gi|31225818|ref|XP_317619.1| ENSANGP00000007283 [Anopheles gambiae]
gi|21300769|gb|EAA12914.1| ENSANGP00000007283 [Anopheles gambiae str.
PEST]
Length = 2383
Score = 695 bits (1794), Expect = 0.0
Identities = 355/690 (51%), Positives = 484/690 (69%), Gaps = 27/690 (3%)
Frame = +1
Query: 6103 SPSNSAENKLYLKHAAHAVRCFAKALMCSPGSRLEDTLRLMQLWFDHGDDKDQDVYFALT 6282
+P ++AE L +A AVR F +++ S G+ L+DTLRL+ LWFDH + ++VY AL
Sbjct: 1711 NPGSAAERNLIKHYAVPAVRGFFQSINLSQGNSLQDTLRLLTLWFDHA--QYEEVYEALV 1768
Query: 6283 ETIFDLPVTTWLEAIPQLMARLDCPDDQKSVQLVLRVLCEIARHRPQAVIYALTVASRSK 6462
E + + TWL+ IPQL+AR+D P + QL+ +L EI + PQA++Y LTVAS+S
Sbjct: 1769 EGMRVIDKNTWLQVIPQLIARIDTPRNLVG-QLINYLLTEIGKTHPQALVYPLTVASKSA 1827
Query: 6463 DVHRSKNAGTVLEKMMEYHSKLVREASLVTEELVRCAILWHEQWHDALDDASRVYFHRRL 6642
R + A +L M E+ + LV + L++EEL+R AILWHEQWH+ L++ASR+YF
Sbjct: 1828 PGTRKQAAHKILNNMCEHSNTLVNQVLLISEELIRVAILWHEQWHEGLEEASRLYFG--- 1884
Query: 6643 QDNNVQAMFDALRNMNDLMQKGAPTTMKEHSFQQTYSSDLKEAGRYVQAFESSGNVKDLN 6822
+ NV+ MF L ++ ++Q+G P T+KE SF Q Y DL EA + + +++S N +DLN
Sbjct: 1885 -EQNVEGMFATLEPLHAMLQRG-PQTLKESSFNQAYGRDLTEAQEWCKHYKNSKNTRDLN 1942
Query: 6823 QAWEIYCSVFKKLRDQLATLNSLDLVYVSPNLVSAKDLELVVPGTYDPSAPIVSIQSFSS 7002
QAW++Y VF+++ QL L SL+L YVSP L++ ++LEL VPG+Y P ++ I S +
Sbjct: 1943 QAWDLYYHVFRRISRQLVQLTSLELQYVSPKLLACRNLELAVPGSYTPGQQLICIASIET 2002
Query: 7003 KMNVITSKQRPRKMVIRGSNGLDYQFLLKGHEDPRQDERVMQLFGLVNTLLANNSETCRR 7182
+ +I+SKQRPRK+ IRGSNG +Y FLLKGHED RQDERVMQLFGLVNTLL N+ +T RR
Sbjct: 2003 NLTIISSKQRPRKLCIRGSNGKNYMFLLKGHEDLRQDERVMQLFGLVNTLLLNDRDTFRR 2062
Query: 7183 NLTIQRYSIVALSKDSGLIGWVPNCDTLHTLVKEYREKKAKIPLSIEHKTLQKLSLETEH 7362
NLTIQRY+++ LS +SGLIGWVP+CDTLH L+++YR+ K K L+IEH+ + +++ + +H
Sbjct: 2063 NLTIQRYAVIPLSTNSGLIGWVPHCDTLHKLIRDYRDSK-KTMLNIEHRIMLRMAPDYDH 2121
Query: 7363 LTLMQKLQLFESALSVTQGEDLRHVLWLKSPSSEVWFDRRTNYTRSVACMSMVGYILGLG 7542
LT+MQK+++FE AL T+G+DL +LWLKSPSSE WFDRRTNY RS+A MSMVGYILGLG
Sbjct: 2122 LTVMQKVEVFEHALDQTKGDDLAKLLWLKSPSSEQWFDRRTNYIRSLAVMSMVGYILGLG 2181
Query: 7543 DRHPSNLMLDRLTGKVVHIDFGDCFEVAMLREKFPERVPFRLTRMLINAMEVTGLDGVYN 7722
DRHPSNLMLDRL+GK++HIDFGDCFEVAM REKFPE++PFRLTRMLINAMEVTG++G Y
Sbjct: 2182 DRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLINAMEVTGIEGTYR 2241
Query: 7723 YTAERVLKMLRTNQESLLAVLEAFVYDPVINWRLVEGMKKDPKTRKDTGGRQNMAGAVLP 7902
T E V+ +LR N++SL+AVLEAFVYDP++NWRL++ + + K+ G +++G++
Sbjct: 2242 RTCESVMNVLRRNKDSLMAVLEAFVYDPLLNWRLLDSDRL--RRSKNAGDMDSVSGSMHE 2299
Query: 7903 SS---------------------------STTDSIMETIKRKLDGTEFVHTDGSTPPEPL 8001
S S T ++ +K KL G +F EP+
Sbjct: 2300 DSLLSYNARRDARLNELNATTGPAAGGQPSATVNVPSGVKDKLTGKDF------GKAEPV 2353
Query: 8002 QVTEQLAMLTEQATSPLNLCQSYIGWCPFW 8091
V Q+ +L +QATS NLCQ YIGWCPFW
Sbjct: 2354 AVNRQIDLLIQQATSNENLCQCYIGWCPFW 2383
Score = 369 bits (946), Expect = e-100
Identities = 300/1150 (26%), Positives = 534/1150 (46%), Gaps = 48/1150 (4%)
Frame = +1
Query: 175 TENRDANQRQAARELSRYVRSELKDEPNTFSDAFLNAIDGRTDIASQSAIYNCMKSNSNI 354
+ N+D Q +A ++LS YV++EL++ P+ D F + I+ + S N
Sbjct: 3 SRNKDV-QNKAIKDLSLYVKTELRETPD---DMFFEDFNHH--------IFEMLTSTDN- 49
Query: 355 DQKRAGIYLIVCLAETHSGNVIRYANYLLKMLNNGNGL----DEDTVKMASKALAFLIAT 522
++K+ GI I CL +G+V+ N + + NN L D +++A+ L L
Sbjct: 50 NEKKGGILAIDCLI---NGDVVNTTNKISRYSNNLRNLLPMSDVCVMQLAANVLVKLALL 106
Query: 523 CKSYAAELVDRCLDHCHEWLGQNVPHSQQPKNQQEIDQIRRLAASHLSRELALATPTAFF 702
S A + + EWL ++ + +R AA + RELA+A PT F+
Sbjct: 107 PGSNGASSFEFDIKRAFEWLSEDRVEN------------KRHAAVLVLRELAVAMPTFFY 154
Query: 703 LRVNLFFKYIFNAVRDKNPAVRIAGIDALHVVLTIVSQREA---KNKTEWFKKCFDEALE 873
+V FF +IF A++D A+R AL VL + SQRE N T+W C+D+A +
Sbjct: 155 QQVGSFFDHIFVAIKDPKAAIREGAGQALRAVLIVTSQREGTKQNNNTQWHMNCYDQAFD 214
Query: 874 GQPNPSQKDDLDRWHAVALILNELLRISDQRFELIRCESSQFIKQKFLKEDEEEGVEWLV 1053
R++ V ++D +F
Sbjct: 215 S-----------RYYDV---------VTDMKF---------------------------- 226
Query: 1054 LTKQQTIVESVTARKLVLERFPKILDCVRQIIPLANKTSSTKQQSSIYLNTVLMQLLPRI 1233
+ ++ ES R LV E++ I V + S Y+ L+ + PR+
Sbjct: 227 FRQNSSVQESALYRALVKEKYDTICQAVLD----------QRSSKSPYVIQTLLAIFPRL 276
Query: 1234 CAFPQCD--RTFQTISFDTSFTIL-----QRNAVAAPAIGMMMLSNPDVHATHIEKTISF 1392
AF + + R + T+L +RNA A ++G + ++ + ++ +
Sbjct: 277 AAFNREEFVRLHLRTVANYLLTLLRSKEKERNA-AFVSLGYIAVAVEKEIEPYTKRIMEL 335
Query: 1393 ISAAIK-KTTNSD----VLDNYFTFLFLFVDAYHEQVTTQIKAIIPQLMDITLSRSLANV 1557
I +A+ K T S V + F + L A +T +IK II ++ LS +L
Sbjct: 336 IGSALPLKDTPSKRKAPVDPSVFMCVMLLGHALKGGITHEIKEIIAPMLSTGLSPALIVC 395
Query: 1558 LKMIMMRIPKLRLNVQDGVMASVYQTLTGSLIP----PKSEPIGRPASPKAILQKAETDP 1725
L+ + +P+ + + G++ + L +P PKS + PA ++ Q+ ++ P
Sbjct: 396 LRELCETVPQAQQEITAGLLKILSYVLMNRPLPQFIVPKSHSVVSPAFLSSLEQQPQSQP 455
Query: 1726 KELQ-----RIVLAVDVLGEFYFSRGALQRIMQYVADYYLTADNVEIRLAAVSSCCEMVV 1890
+ Q IVLA+ LG+F F +L + +Q AD++L ++ EIR+ AV +C ++
Sbjct: 456 PQQQVHDTATIVLALQTLGKFSFEGCSLLQFVQRCADHFLNSEQQEIRIEAVHTCTFLLK 515
Query: 1891 PFVGVYKKVTSDKRNSLLQTIYGVLRAVCSVIVNDQDVRVRMQVISCFGQMPRPFLAHLA 2070
+ + +D +L QT+ VL + V + D D VR++V+ + F LA
Sbjct: 516 LALQAAESNGNDVSETLTQTLSSVLEKILVVGITDVDPAVRLRVLK---SLDESFDTQLA 572
Query: 2071 QPEMLEVQFMALHDEKLEMQQACVTLLGRLAELNPAXXXXXXXXXXXXXXSQMQQSGQAR 2250
QP L + +HDE E+++ + ++GRL+ +NPA ++++ SG +R
Sbjct: 573 QPWFLSSLLVTIHDEVFEIRELAIIIIGRLSTINPAYVMPSLRKTMVQLLTELEHSGVSR 632
Query: 2251 LEQHSAKMIAQLAKQSPKFMRPYVGSLMIAMIPKLRNDQKYAEVTAQVLNAVSEIA-VIG 2427
++ SA+M+ L +P+ + Y+ ++ ++PKL+ + V VL A+ ++A VIG
Sbjct: 633 NKEQSARMLDHLIVSTPRLVASYMRPILTILVPKLKEPDQNPSVVLNVLRAIGDLAEVIG 692
Query: 2428 GAEIVKNLKP-LFEKLTHMINDSSSLHKREAALRAIGGICRSTAYVVDPYRDYPSLLDDL 2604
G +++ L + L M++D+ S KR AL G + +T VV PY YP+L+D L
Sbjct: 693 GHHVLQKWSDELLQLLLDMLSDAGSTEKRAVALWTFGQLVSATGQVVVPYNKYPNLIDIL 752
Query: 2605 LRILKTVMSNTMRREAIKTLGILGAIDPYTHKVFTGSVQSSTAISTALSLPISETDSKDP 2784
+ LKT +RRE I+ LG+LGA+DPY HK+ G + S T+ + +S+ ++TD
Sbjct: 753 INFLKTEQQLYVRRETIRVLGLLGALDPYKHKMNRGLIDSQTSANILISVD-TKTDEHTD 811
Query: 2785 RQDIIHWFNYEKCTLEEFYPAITIANLMLMMQDED-SQSYAEIAQAIVTIFRSLGDMAPL 2961
N L+E+YPA+ I+ LM +++D S + + QAI F SLG
Sbjct: 812 LSTSEMLINM-STQLDEYYPAVVISTLMKILRDPTLSNHHLSVVQAITFTFTSLGIKGVP 870
Query: 2962 YTEQVIPRLIEVCRRATESSNRANLREFFLQQLANFVAIIRKHAAPYMPAIFTIIADAW- 3138
Y QV+P L+ A S L+E+ QQL+ ++I+++H +M IF +I W
Sbjct: 871 YLSQVLPCLLRNIVTAEMS-----LKEYLFQQLSTLISIVKQHIIGFMDDIFELIKTFWT 925
Query: 3139 ----------------KEDISVKMVVIEVLTDMGTAIGNDFSKYTGELIPYLLTVLQTDK 3270
S++ +I ++ + A+G +F Y +L+P +L VL D
Sbjct: 926 TGGAGVPGGGGSSSSTASAASLQPTIINLVEKIAIALGCEFKVYLPQLMPQILRVLLHDT 985
Query: 3271 TKERVLTVKVMESIQKLTHCIXXXXXXXXXXXXXXXXXFSLKLSIRNTALSTVLHMTQQV 3450
+K+R +TVK++ +++ + + + L++ TAL T+ ++ + +
Sbjct: 986 SKDRAVTVKLLGAMRNFGNNLDDYLHLIIPAIVKLFEPLDIPLNVSITALQTINYLAEVL 1045
Query: 3451 DVSAYAPRMM 3480
D + ++ R++
Sbjct: 1046 DFTDFSSRIV 1055
Score = 350 bits (899), Expect = 3e-94
Identities = 224/625 (35%), Positives = 316/625 (49%), Gaps = 4/625 (0%)
Frame = +1
Query: 3946 ITKQRLNKDALMPQWKNENLTSKDEWLQWLMKIRIGFLTYGSSPSLRAASSLGDQHPHLA 4125
I K ++ L +K SKD+WL+WL ++ I L +P+LR+ ++L +P L
Sbjct: 1147 IKKFPVSMSDLEAMFKANRRVSKDDWLEWLRRLSIILLKESKNPALRSCATLAQNYPQLL 1206
Query: 4126 RDLFPAAFMSVWTELDSDVQNDLTSCLLRAIST-GIPELIQTILNLAEFMDHSEKGPLPI 4302
+DLF AAF+S W++L ++ DL L +A++ +PE+ QT+LNLAEFM+H E PL I
Sbjct: 1207 KDLFNAAFVSCWSDLSEKLKQDLAHSLTQALTVQDLPEITQTVLNLAEFMEHCESYPLKI 1266
Query: 4303 SHDVLGRWAEQTKAFAKACRYKEMSVLKKSGSMQTTFTRKVKLEPNDCQSLITYANKLNV 4482
+LG A + +A+AKA YKE + Q+ F +SLI NKL
Sbjct: 1267 DSKILGERAMECRAYAKALHYKEDEFHRTDDPPQSLF-----------ESLILINNKLQQ 1315
Query: 4483 QEEAAGVVRYAERNEMN---FQMRGRWYEKLNEWEKALGAYELEEKKKSSCPNLQVYDEK 4653
+E A G++ YA R+ + +++ RWYEKL+ WE+A Y EK KS+ +L+
Sbjct: 1316 KEAAEGLLEYAGRHRSSAEEMKVQVRWYEKLHSWEQARSLYS--EKLKSNPNDLE----- 1368
Query: 4654 DHLMTPXXXXXXXXXRMHEMRCLEALGRWDELNSKSVVWADQRGNRNDSVRDEINKKQLD 4833
R+ EMRCLEALG W LN+ + D G+ S
Sbjct: 1369 --------------SRLGEMRCLEALGEWSALNAVTTQNWDALGSEGQS----------- 1403
Query: 4834 HKMAVIAARGAWAVDNWERMADYVSVISENTQDGAMLRAVVAVHNDENTKAMGLIEKVRE 5013
K +AA AW + +W+ M +V I E+TQDGA RAV+AVHN++ A LI+ R+
Sbjct: 1404 -KAGRLAAAAAWGLQDWDGMHRFVRCIPEDTQDGAFYRAVLAVHNEQYALAQSLIDSTRD 1462
Query: 5014 MIDSELTAMANESYERAYIPMVSVQQMAELEEAIEYKTRPERRPRIALLWSRRLQGCRRN 5193
++D+ELTAMA ESYERAY MV VQ +AELEE I+YK PERR I +W RL G +R
Sbjct: 1463 LLDTELTAMAGESYERAYGAMVCVQMLAELEEVIQYKLIPERRETIKSMWWDRLLGGQRL 1522
Query: 5194 VEQWQRLIMLRGLVLSPQEMHPLRVKFSSMCRKQGKNSMSRAVLRELLSLPANSDLVRAK 5373
VE WQR+I + LVLSP+E +KF+S+CRK G +S L LL +L
Sbjct: 1523 VEDWQRVIQVHSLVLSPKEDIRTWLKFASLCRKNGSLKLSEKTLTMLLEYDPMENL-SEP 1581
Query: 5374 APFDKPLLVLALAKQLYQDDHKDEAIRALEDLANHWNKRINPIPKATGRELIPPSTKEPA 5553
P DKP + A K L+ + EA L ++ + G + E
Sbjct: 1582 LPIDKPHVTFAYTKHLHMAGYTKEAYDHLNRFVASFSPQAFTASSGAGGQ--DDLKDENR 1639
Query: 5554 RICAKVLLKLGEWTELKSKTSNNMQVGELSFVRQQVSPQYRTKESRTPETIAFENTINYY 5733
R+ A+ LKLG W S T N+ L + Y
Sbjct: 1640 RLLARCFLKLGMWQ--SSSTGGNLVKDHL-----------------------INGILVCY 1674
Query: 5734 QQATQYDPGWHKVWHKLASTHFYAV 5808
+AT++DP W+K WH A +F V
Sbjct: 1675 SRATKHDPNWYKAWHNWAYMNFEVV 1699
>gi|50759309|ref|XP_417614.1| PREDICTED: similar to FKBP-rapamycin
associated protein (FRAP) (Rapamycin target protein)
[Gallus gallus]
Length = 2500
Score = 694 bits (1792), Expect = 0.0
Identities = 364/692 (52%), Positives = 488/692 (69%), Gaps = 15/692 (2%)
Frame = +1
Query: 6049 SNSSLPPQHHHVSPLSNDSPSNSAEN--KLYLKHAAHAVRCFAKALMCSPGSRLEDTLRL 6222
SNS + SP+ + E+ K L + AV+ F +++ S G+ L+DTLR+
Sbjct: 1824 SNSESDAESTENSPIPSPVQKKVTEDLSKTLLMYTVPAVQGFFRSISLSRGNNLQDTLRV 1883
Query: 6223 MQLWFDHGDDKDQDVYFALTETIFDLPVTTWLEAIPQLMARLDCPDDQKSVQLVLRVLCE 6402
+ LWFD+G D V AL E + + + TWL+ IPQL+AR+D P +L+ ++L +
Sbjct: 1884 LTLWFDYGHWPD--VNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVG-RLIHQLLTD 1940
Query: 6403 IARHRPQAVIYALTVASRSKDVHRSKNAGTVLEKMMEYHSKLVREASLVTEELVRCAILW 6582
I R+ PQA+IY LTVAS+S R A +L+ M E+ + LV++A +V+EEL+R AILW
Sbjct: 1941 IGRYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHSNTLVQQAMMVSEELIRVAILW 2000
Query: 6583 HEQWHDALDDASRVYFHRRLQDNNVQAMFDALRNMNDLMQKGAPTTMKEHSFQQTYSSDL 6762
HE WH+ L++ASR+YF R NV+ MF+ L ++ +M++G P T+KE SF Q Y DL
Sbjct: 2001 HEMWHEGLEEASRLYFGER----NVKGMFEVLEPLHAMMERG-PQTLKETSFNQAYGRDL 2055
Query: 6763 KEAGRYVQAFESSGNVKDLNQAWEIYCSVFKKLRDQLATLNSLDLVYVSPNLVSAKDLEL 6942
EA + + + SGNVKDL QAW++Y VF+++ QL L SL+L YVSP L+ +DLEL
Sbjct: 2056 MEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLEL 2115
Query: 6943 VVPGTYDPSAPIVSIQSFSSKMNVITSKQRPRKMVIRGSNGLDYQFLLKGHEDPRQDERV 7122
VPGTYDP+ PI+ IQS + + VITSKQRPRK+ + GSNG ++ FLLKGHED RQDERV
Sbjct: 2116 AVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERV 2175
Query: 7123 MQLFGLVNTLLANNSETCRRNLTIQRYSIVALSKDSGLIGWVPNCDTLHTLVKEYREKKA 7302
MQLFGLVNTLLAN+ + R+NL+IQRY+++ LS +SGLIGWVP+CDTLH L+++YREKK
Sbjct: 2176 MQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKK- 2234
Query: 7303 KIPLSIEHKTLQKLSLETEHLTLMQKLQLFESALSVTQGEDLRHVLWLKSPSSEVWFDRR 7482
KI L+IEH+ + +++ + +HLTLMQK+++FE A++ T G+DL +LWLKSPSSEVWFDRR
Sbjct: 2235 KILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRR 2294
Query: 7483 TNYTRSVACMSMVGYILGLGDRHPSNLMLDRLTGKVVHIDFGDCFEVAMLREKFPERVPF 7662
TNYTRS+A MSMVGYILGLGDRHPSNLMLDRL+GK++HIDFGDCFEVAM REKFPE++PF
Sbjct: 2295 TNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPF 2354
Query: 7663 RLTRMLINAMEVTGLDGVYNYTAERVLKMLRTNQESLLAVLEAFVYDPVINWRL----VE 7830
RLTRML NAMEVTGLDG Y T V+++LR +++S++AVLEAFVYDP++NWRL ++
Sbjct: 2355 RLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDKMLD 2414
Query: 7831 GMKKDPKTRKDTGGRQNMA-------GAVLPSSSTTDS--IMETIKRKLDGTEFVHTDGS 7983
GM+ K TG + G V P + + I+ ++ KL G +F H
Sbjct: 2415 GMELGETAHKKTGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSH---- 2470
Query: 7984 TPPEPLQVTEQLAMLTEQATSPLNLCQSYIGW 8079
E L V Q+ +L +QATS NLCQ YIGW
Sbjct: 2471 --DETLDVPTQVELLIKQATSHENLCQCYIGW 2500
Score = 431 bits (1109), Expect = e-118
Identities = 321/1092 (29%), Positives = 531/1092 (48%), Gaps = 72/1092 (6%)
Frame = +1
Query: 421 RYANYLLKMLNNGNGLDEDTVKMASKALAFLIATCKSYAAELVDRCLDHCHEWLGQNVPH 600
R+ANYL +L + D ++MASKA+ L ++ AE V+ + EWLG +
Sbjct: 53 RFANYLRNLLPSN---DPVVMEMASKAIGRLAMAGDTFTAEYVEFEVKRALEWLGAD--- 106
Query: 601 SQQPKNQQEIDQIRRLAASHLSRELALATPTAFFLRVNLFFKYIFNAVRDKNPAVRIAGI 780
+N+ RR AA + RELA++ PT FF +V FF IF AV D A+R +
Sbjct: 107 ----RNEG-----RRHAAVLVLRELAISVPTFFFQQVQPFFDNIFVAVWDPKQAIREGAV 157
Query: 781 DALHVVLTIVSQREAKN--KTEWFKKCFDEALEGQPNPSQKDDL----DRWHAVALILNE 942
AL L + +QRE K K +W++ ++EA +G K+ DR H LILNE
Sbjct: 158 SALRACLILTTQREPKEMQKPQWYRHTYEEAEKGFDETLAKEKGMNRDDRIHGALLILNE 217
Query: 943 LLRISDQRFELIRCE-----SSQFIKQKFLKE---------------------------- 1023
L+RIS E +R E Q + K+ K+
Sbjct: 218 LVRISSMEGERLREEMEEITQQQLVHDKYCKDLMGFSTKPRHITPFTSFQSLQPSQSNAL 277
Query: 1024 ------DEEEGVEWLV---LTKQQTIVESVTARKLVLERFPKILDCVRQIIPLANKTSST 1176
+ +G+ + + T+VES R L+ E+F ++ V L +TS
Sbjct: 278 AGLLGYNAHQGIMGFATSPMPAKSTLVESRCCRDLMEEKFDQVCQWV-----LKCRTS-- 330
Query: 1177 KQQSSIYLNTVLMQLLPRICAFPQCDRTFQTISFDTSFTIL------QRNAVAAPAIGMM 1338
++S+ TVL LLPR+ AF T DT +L + A A+G++
Sbjct: 331 --KNSLIQMTVL-NLLPRLAAFRPSAFTADQYLPDTMNHVLSCVKKEKERTAAFQALGLL 387
Query: 1339 MLSNPDVHATHIEKTISFISAAI-------KKTTNSDVLDNYFTFLFLFVDAYHEQVTTQ 1497
++ ++ K + I AA+ K+ + V FT + + A +
Sbjct: 388 SVAVRSEFQAYLPKVLEIIKAALPPKDFAHKRQKSVQVDATVFTCISMLARAMGPSIQQD 447
Query: 1498 IKAIIPQLMDITLSRSLANVLKMIMMRIPKLRLNVQDGVMASVYQTLTGSLIPPKSEPIG 1677
IK ++ ++ + LS +L VL + +IP+L+ ++QDG++ + L +P+
Sbjct: 448 IKELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLM-------HKPLR 500
Query: 1678 RPASPKAILQKAET-------DPKELQRIVLAVDVLGEFYFSRGALQRIMQYVADYYLTA 1836
P PK + + + + ++ I LA+ LG F F +L + +++ AD++L +
Sbjct: 501 HPGMPKGLAHQLASPSLTNIPEASDVGSITLALRTLGSFEFEGHSLTQFVRHCADHFLNS 560
Query: 1837 DNVEIRLAAVSSCCEMVVPFVGVYKKVTSDKRNSLLQTIYGVLRAVCSVIVNDQDVRVRM 2016
++ EIR+ A +C ++ P + + + +Q + VL + V + D D +R
Sbjct: 561 EHKEIRMEAARTCSRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLLVVGITDPDPDIRF 620
Query: 2017 QVISCFGQMPRPFLAHLAQPEMLEVQFMALHDEKLEMQQACVTLLGRLAELNPAXXXXXX 2196
V++ + F AHLAQ E L+ F+AL+D+ E+++ + +GRL+ +NPA
Sbjct: 621 CVLASLDER---FDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSSMNPAFVMPFL 677
Query: 2197 XXXXXXXXSQMQQSGQARLEQHSAKMIAQLAKQSPKFMRPYVGSLMIAMIPKLRNDQKYA 2376
++++ SG R+++ SA+M+ L +P+ +RPY+ ++ A+I KL++
Sbjct: 678 RKMLIQILTELEHSGVGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALIVKLKDPDPDP 737
Query: 2377 E--VTAQVLNAVSEIAVIGGAEIVKNLKPLFEKLTHMINDSSSLHKREAALRAIGGICRS 2550
V VL + E+A + G E+ K + LF + M+ DSS L KR+ AL +G + S
Sbjct: 738 NPGVINNVLATIGELAQVSGLEMRKWVDELFIIIMDMLQDSSLLAKRQVALWTLGQLVAS 797
Query: 2551 TAYVVDPYRDYPSLLDDLLRILKTVMSNTMRREAIKTLGILGAIDPYTHKVFTGSV-QSS 2727
T YVV+PYR YP+LL+ LL LKT + RREAI+ LG+LGA+DPY HKV G + QS
Sbjct: 798 TGYVVEPYRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHKVNIGMIDQSR 857
Query: 2728 TAISTALSLPISETDSKDPRQDIIHWFNYEKCTLEEFYPAITIANLMLMMQDED-SQSYA 2904
A + +LS S DS D + N L+EFYPA+++ LM + +D+ SQ +
Sbjct: 858 DASAVSLSESKSSQDSSDYSTSEM-LVNMGNLPLDEFYPAVSMVALMRIFRDQSLSQHHT 916
Query: 2905 EIAQAIVTIFRSLGDMAPLYTEQVIPRLIEVCRRATESSNRANLREFFLQQLANFVAIIR 3084
+ QAI IF+SLG + QV+P + V R + +REF QQL V+ +R
Sbjct: 917 MVVQAITFIFKSLGLKCVQFLPQVMPTFLNVIRVCDGA-----IREFLFQQLGMLVSFVR 971
Query: 3085 KHAAPYMPAIFTIIADAWKEDISVKMVVIEVLTDMGTAIGNDFSKYTGELIPYLLTVLQT 3264
H PYM I T++ D W + S++ +I ++ + A+G +F Y +LIP++L V
Sbjct: 972 SHIRPYMDEIVTLMRDFWVMNNSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMH 1031
Query: 3265 DKTKERVLTVKVMESIQKLTHCIXXXXXXXXXXXXXXXXXFSLKLSIRNTALSTVLHMTQ 3444
D ++ R+++VK++ +IQ + + R AL TV +T+
Sbjct: 1032 DNSQSRIVSVKLLNAIQLFGANLDDYLHLLLPPIVKLFDAPDAPVVARKAALETVDRLTE 1091
Query: 3445 QVDVSAYAPRMM 3480
+D + YA R++
Sbjct: 1092 SLDFTDYASRII 1103
Score = 315 bits (807), Expect = 1e-83
Identities = 219/659 (33%), Positives = 317/659 (47%), Gaps = 48/659 (7%)
Frame = +1
Query: 3976 LMPQWKNENLTSKDEWLQWLMKIRIGFLTYGSSPSLRAASSLGDQHPHLARDLFPAAFMS 4155
L W SKD+WL+WL ++ + L SSPSLR+ +L + +ARDLF AAF+S
Sbjct: 1212 LQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVS 1271
Query: 4156 VWTELDSDVQNDLTSCLLRAI-STGIPELIQTILNLAEFMDHSEKGPLPISHD----VLG 4320
W+EL+ D Q++L + A+ S I E+ QT+LNLAEFM+HS+KGPLP+ D +LG
Sbjct: 1272 CWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLG 1331
Query: 4321 RWAEQTKAFAKACRYKEMSVLKKSGSMQTTFTRKVKLEPNDCQSLITYANKLNVQEEAAG 4500
A + +A+AKA YKE+ K P +SLI+ NKL E AAG
Sbjct: 1332 ERAAKCRAYAKALHYKELEFQKGP-------------TPAILESLISINNKLQQPEAAAG 1378
Query: 4501 VVRYAERNEMNFQMRGRWYEKLNEWEKALGAYELEEKKKSSCPNLQVYDEKDHLMTPXXX 4680
V+ YA ++ +++ WYEKL+EWE AL AY+ + P L
Sbjct: 1379 VLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPELM-------------- 1424
Query: 4681 XXXXXXRMHEMRCLEALGRWDELNSKSVVWADQRGNRNDSVRDEINKKQLDHKMAVIAAR 4860
+ MRCLEALG W +L+ + + V DE K MA +AA
Sbjct: 1425 -------LGRMRCLEALGEWGQLHQQCC-------EKWTQVNDETQAK-----MARMAAA 1465
Query: 4861 GAWAVDN--------------------------------WERMADYVSVISENTQDGAML 4944
AW + + W+ M +Y +I +T DGA
Sbjct: 1466 AAWGLGDSLRKGNLLLCGTVARLNVVAMAMAVAAAESRQWDSMEEYTCMIPRDTHDGAFY 1525
Query: 4945 RAVVAVHNDENTKAMGLIEKVREMIDSELTAMANESYERAYIPMVSVQQMAELEEAIEYK 5124
RAV+A+H D + A I+K R+++D+ELTAMA ESY RAY MVS Q ++ELEE I+YK
Sbjct: 1526 RAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCQMLSELEEVIQYK 1585
Query: 5125 TRPERRPRIALLWSRRLQGCRRNVEQWQRLIMLRGLVLSPQEMHPLRVKFSSMCRKQGK- 5301
PERR I +W RLQGC+R VE WQR++M+R LV++P E +K++S+C K G+
Sbjct: 1586 LVPERREIIRQIWWERLQGCQRIVEDWQRILMVRSLVVNPHEDMRTWLKYASLCGKSGRL 1645
Query: 5302 -------NSM--SRAVLRELLSLPAN-SDLVRAKAPFDKPLLVLALAKQLYQDDHKDEAI 5451
NS R + E + S + P P + A K +++ K +A
Sbjct: 1646 VSIINPYNSFFNDRQLYGEYEMEDGDPSRQLDHPLPTVHPQVTYAYMKHMWKSARKIDAF 1705
Query: 5452 RALEDLANHWNKRINPIPKATGRELIPPSTKEPARICAKVLLKLGEWTELKSKTSNNMQV 5631
+ ++ ++ ++ +E ++ A+ LKLGEW N+Q
Sbjct: 1706 QHMQHFVQTMQQQAQHAIATEDQQ----HKQELHKLMARCFLKLGEW-------QLNLQ- 1753
Query: 5632 GELSFVRQQVSPQYRTKESRTPETIAFENTINYYQQATQYDPGWHKVWHKLASTHFYAV 5808
ES P+ + YY AT++D W+K WH A +F AV
Sbjct: 1754 --------------GINESTIPK------VLQYYSAATEHDRNWYKAWHAWAVMNFEAV 1792
>gi|15292447|gb|AAK93492.1| SD02269p [Drosophila melanogaster]
Length = 760
Score = 677 bits (1747), Expect = 0.0
Identities = 350/686 (51%), Positives = 483/686 (70%), Gaps = 35/686 (5%)
Frame = +1
Query: 6139 KHAAHAVRCFAKALMCSPGSRLEDTLRLMQLWFDHGDDKDQDVYFALTETIFDLPVTTWL 6318
++A AV+ F +++ G+ L+DTLRL+ LWFD+G+ + VY AL + + + TWL
Sbjct: 90 RYAVPAVQGFFRSISLIKGNSLQDTLRLLTLWFDYGNHAE--VYEALLSGMKLIEINTWL 147
Query: 6319 EAIPQLMARLDCPDDQKSVQLVLRVLCEIARHRPQAVIYALTVASRSKDVHRSKNAGTVL 6498
+ IPQL+AR+D Q QL+ ++L +I ++ PQA++Y LTVAS+S + R A +L
Sbjct: 148 QVIPQLIARIDT-HRQLVGQLIHQLLMDIGKNHPQALVYPLTVASKSASLARRNAAFKIL 206
Query: 6499 EKMMEYHSKLVREASLVTEELVRCAILWHEQWHDALDDASRVYFHRRLQDNNVQAMFDAL 6678
+ M ++ LV +A + +EEL+R AILWHEQWH+ L++ASR+YF D NV+ MF+ L
Sbjct: 207 DSMRKHSPTLVEQAVMCSEELIRVAILWHEQWHEGLEEASRLYFG----DRNVKGMFEIL 262
Query: 6679 RNMNDLMQKGAPTTMKEHSFQQTYSSDLKEAGRYVQAFESSGNVKDLNQAWEIYCSVFKK 6858
++ ++++G P T+KE SF Q Y +L EA + Q +++S V DL++AW+IY VF+K
Sbjct: 263 EPLHAMLERG-PQTLKETSFSQAYGRELTEAYEWSQRYKTSAVVMDLDRAWDIYYHVFQK 321
Query: 6859 LRDQLATLNSLDLVYVSPNLVSAKDLELVVPGTYDPSAPIVSIQSFSSKMNVITSKQRPR 7038
+ QL L SL+L YVSP L++ KDLEL VPG+Y+P ++ I + + VITSKQRPR
Sbjct: 322 ISRQLPQLTSLELPYVSPKLMTCKDLELAVPGSYNPGQELIRISIIKTNLQVITSKQRPR 381
Query: 7039 KMVIRGSNGLDYQFLLKGHEDPRQDERVMQLFGLVNTLLANNSETCRRNLTIQRYSIVAL 7218
K+ IRGSNG DY +LLKGHED RQDERVMQLF LVNTLL ++ +T RRNL IQRY+++ L
Sbjct: 382 KLCIRGSNGKDYMYLLKGHEDLRQDERVMQLFSLVNTLLLDDPDTFRRNLAIQRYAVIPL 441
Query: 7219 SKDSGLIGWVPNCDTLHTLVKEYREKKAKIPLSIEHKTLQKLSLETEHLTLMQKLQLFES 7398
S +SGLIGWVP+CDTLHTL+++YR+KK K+PL+ EH+T+ + + +HLTLMQK+++FE
Sbjct: 442 STNSGLIGWVPHCDTLHTLIRDYRDKK-KVPLNQEHRTMLNFAPDYDHLTLMQKVEVFEH 500
Query: 7399 ALSVTQGEDLRHVLWLKSPSSEVWFDRRTNYTRSVACMSMVGYILGLGDRHPSNLMLDRL 7578
AL TQG+DL +LWLKSPSSE+WF+RR NYTRS+A MSMVGYILGLGDRHPSNLMLDR+
Sbjct: 501 ALGQTQGDDLAKLLWLKSPSSELWFERRNNYTRSLAVMSMVGYILGLGDRHPSNLMLDRM 560
Query: 7579 TGKVVHIDFGDCFEVAMLREKFPERVPFRLTRMLINAMEVTGLDGVYNYTAERVLKMLRT 7758
+GK++HIDFGDCFEVAM REKFPE++PFRLTRMLI AMEVTG++G Y T E V+ +LR
Sbjct: 561 SGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLIKAMEVTGIEGTYRRTCESVMLVLRR 620
Query: 7759 NQESLLAVLEAFVYDPVINWRLVEGMKKD---------PKTRKDTGGRQNMAGAV---LP 7902
N++SL+AVLEAFVYDP++NWRL++ KK P R +G + +++ +V LP
Sbjct: 621 NKDSLMAVLEAFVYDPLLNWRLLDVDKKGNDAVAGAGAPGGRGGSGMQDSLSNSVEDSLP 680
Query: 7903 -----------------------SSSTTDSIMETIKRKLDGTEFVHTDGSTPPEPLQVTE 8013
++S +++ +K KL GT+F T+ S +
Sbjct: 681 MAKSKPYDPTLQQGGLHNNVADETNSKASQVIKRVKCKLTGTDF-QTEKSVNEQ-----S 734
Query: 8014 QLAMLTEQATSPLNLCQSYIGWCPFW 8091
Q+ +L +QAT+ NLCQ YIGWCPFW
Sbjct: 735 QVELLIQQATNNENLCQCYIGWCPFW 760
Score = 38.1 bits (87), Expect = 3.6
Identities = 16/47 (34%), Positives = 27/47 (57%)
Frame = +1
Query: 5668 QYRTKESRTPETIAFENTINYYQQATQYDPGWHKVWHKLASTHFYAV 5808
Q + ++S P+ I + + +++AT YDP W+K WH A +F V
Sbjct: 12 QNKLQDSIRPDAI--QGALECFEKATSYDPNWYKAWHLWAYMNFKVV 56
>gi|46127511|ref|XP_388309.1| hypothetical protein FG08133.1
[Gibberella zeae PH-1]
gi|42549089|gb|EAA71932.1| hypothetical protein FG08133.1 [Gibberella
zeae PH-1]
Length = 2423
Score = 639 bits (1647), Expect = 0.0
Identities = 337/716 (47%), Positives = 473/716 (65%), Gaps = 51/716 (7%)
Frame = +1
Query: 6097 NDSPSNSAENKLYLKHAAHAVRCFAKALMCSPGSRLEDTLRLMQLWFDHGDDKDQDVYFA 6276
N+ + A+ + ++H AV+ F K++ S GS L+DTLRL+ LWF HG D V A
Sbjct: 1723 NEGTLSRADQSMVIEHVVPAVKGFFKSIALSEGSSLQDTLRLLTLWFTHGGSAD--VTSA 1780
Query: 6277 LTETIFDLPVTTWLEAIPQLMARLDCPDDQKSVQLVLRVLCEIARHRPQAVIYALTVASR 6456
+TE ++ V TWLE IPQL+AR++ P+ ++ Q V +L ++ R PQA++Y LTVA +
Sbjct: 1781 VTEGFANVSVDTWLEVIPQLIARINQPN-KRVQQSVHNLLADVGRAHPQALVYPLTVAMK 1839
Query: 6457 S-KDVHRSKNAGTVLEKMMEYHSKLVREASLVTEELVRCAILWHEQWHDALDDASRVYFH 6633
S ++ RS++A +++ M ++ + LV +A +V+ EL+R A+LWHE WH+ L++ASR+YF
Sbjct: 1840 SWQNTRRSRSAAQIMDSMRQHSANLVAQADIVSHELIRVAVLWHELWHEGLEEASRLYFG 1899
Query: 6634 RRLQDNNVQAMFDALRNMNDLMQKGAPTTMKEHSFQQTYSSDLKEAGRYVQAFESSGNVK 6813
D+N++ MF L +++L+++G P T++E SF Q + DLKEA + + +E+S +V
Sbjct: 1900 ----DHNIEGMFATLEPLHELLERG-PETLREISFAQAFGRDLKEAQDWCRQYETSQDVN 1954
Query: 6814 DLNQAWEIYCSVFKKLRDQLATLNSLDLVYVSPNLVSAKDLELVVPGTYDPSAPIVSIQS 6993
DLNQAW++Y VF+++ QL + +L+L Y SP L++AK+L+L VPGTY PIV I S
Sbjct: 1955 DLNQAWDLYYQVFRRISRQLPQVTTLELTYCSPKLLNAKNLDLAVPGTYKSGQPIVRIMS 2014
Query: 6994 FSSKMNVITSKQRPRKMVIRGSNGLDYQFLLKGHEDPRQDERVMQLFGLVNTLLANNSET 7173
F + +VI SKQRPRK+ + GS+G Y FLLKGHED RQDERVMQLFGL NTLL+++SE
Sbjct: 2015 FDTTFSVINSKQRPRKLNVNGSDGKSYAFLLKGHEDIRQDERVMQLFGLCNTLLSHDSEC 2074
Query: 7174 CRRNLTIQRYSIVALSKDSGLIGWVPNCDTLHTLVKEYREKKAKIPLSIEHKTLQKLSLE 7353
+R+L IQRY + LS++SGL+GWVPN DTLH L++EYRE + KI L+IEH+ + +++ +
Sbjct: 2075 FKRHLNIQRYPAIPLSQNSGLLGWVPNSDTLHVLIREYRESR-KILLNIEHRIMLQMAPD 2133
Query: 7354 TEHLTLMQKLQLFESALSVTQGEDLRHVLWLKSPSSEVWFDRRTNYTRSVACMSMVGYIL 7533
++LTLMQK+++F AL T G+DL VLWLKS SSE W +RRTNYTRS+ MSMVGYIL
Sbjct: 2134 YDNLTLMQKVEVFGYALDNTTGQDLYRVLWLKSKSSEAWLERRTNYTRSLGVMSMVGYIL 2193
Query: 7534 GLGDRHPSNLMLDRLTGKVVHIDFGDCFEVAMLREKFPERVPFRLTRMLINAMEVTGLDG 7713
GLGDRHPSNLMLDR+TGK++HIDFGDCFEVAM REK+PERVPFRLTRML AMEV+ ++G
Sbjct: 2194 GLGDRHPSNLMLDRVTGKIIHIDFGDCFEVAMKREKYPERVPFRLTRMLTYAMEVSNIEG 2253
Query: 7714 VYNYTAERVLKMLRTNQESLLAVLEAFVYDPVINWRLVEG-MKKDPKTRKDTGGRQNMAG 7890
+ T E V+++LR N+ES++AVLEAF++DP++ WRL P R D + G
Sbjct: 2254 SFRITCENVMRVLRDNKESVMAVLEAFIHDPLLTWRLTNAPSPAGPNFRNDRDTAMPVPG 2313
Query: 7891 AVL---------------------PSSST-----TDS----------------------- 7923
V PS T T+S
Sbjct: 2314 GVRARRQSILDSDVAPSELLNAPEPSIQTRARARTNSSAGVPETNGGAPEVESQNARAVE 2373
Query: 7924 IMETIKRKLDGTEFVHTDGSTPPEPLQVTEQLAMLTEQATSPLNLCQSYIGWCPFW 8091
+++ +++KL G +F + E L V Q+ L +AT NLCQ YIGWC FW
Sbjct: 2374 VLDRVQQKLTGRDFKNN------EELDVINQVNKLIMEATKLENLCQHYIGWCSFW 2423
Score = 301 bits (770), Expect = 2e-79
Identities = 255/1114 (22%), Positives = 492/1114 (43%), Gaps = 8/1114 (0%)
Frame = +1
Query: 163 RSRITENRDANQRQAARELSRYVRSELKDEPNTFSDAFLNAIDGRTDIASQSAIYNCMKS 342
+S+++++ REL +L E +F NA++ R I +
Sbjct: 20 KSKVSDDLRKRSAVQLRELVVICHRDLSPE---LFQSFYNAVNNR--------ITQLITH 68
Query: 343 NSNIDQKRAGIYLIVCLAETHSGNV-IRYANYLLKMLNNGNGLDEDTVKMASKALAFLIA 519
S+ ++ GIY + L + +V ++Y + + G D + ++ A+ AL L
Sbjct: 69 GSDSSERLGGIYALDALIDFEGVDVAVKYTRFTQNLKTILRGKDINPMQPAAIALGKLCR 128
Query: 520 TCKSYAAELVDRCLDHCHEWLGQNVPHSQQPKNQQEIDQIRRLAASHLSRELALATPTAF 699
S +E+VD ++ EWL Q + + RR +A + RELA + PT
Sbjct: 129 PGGSMISEVVDSEVNTALEWL------------QNDRVEERRYSAVLVLRELARSAPTLM 176
Query: 700 FLRVNLFFKYIFNAVRDKNPAVRIAGIDALHVVLTIVSQREAKNKTEWFKKCFDEALEGQ 879
+ + F +I+ +RD +R + + I+ +R+ + K W ++EA +G
Sbjct: 177 YQYIPTIFDWIWIGLRDSRQLIRATSAETVSACFRILRERDQEMKQRWMSNIYNEAKQGL 236
Query: 880 PNPSQKDDLDRWHAVALILNELLRISDQRFELIRCESSQFIKQKFLKEDEEEGVEWLVLT 1059
+ + ++ H L+L ELL +++E ++ E +
Sbjct: 237 ----KVNTVESIHGSLLVLKELLEQGAM----------------YMQEHYQQACEIVFKH 276
Query: 1060 KQQTIVESVTARKLVLERFPKILDCVRQIIPLANKTSSTKQQSSIYLNTVLMQLLPRICA 1239
K T RK V+ P + A+ + + +YL+ +L + R A
Sbjct: 277 KDH---RDPTIRKTVVLLIPDLAS-----YSPADFAHTWLHKFMVYLSGMLKKDKERNDA 328
Query: 1240 FPQCDRTFQTISFDTSFTILQRNAVAAPAIGMMMLSNPDVHATHIEKTISFISAAIK-KT 1416
F AIG + S A +++ + ++ + ++
Sbjct: 329 FL--------------------------AIGNIANSVKSAIAPYLDGVLIYVREGLSVQS 362
Query: 1417 TNSDVLDNYFTFLFLFVDAYHEQVTTQIKAIIPQLMDITLSRSLANVLKMIMMRIPKLRL 1596
+D F + A + ++ ++A++ + L+ L L + IP ++
Sbjct: 363 RKRGSVDPVFDCISRLAVAVGQTLSKYMEALLDPIFACDLTPKLTQALVDMAFYIPPVKP 422
Query: 1597 NVQDGVMASVYQTLTGSLIPPKSEPIGRPASPKAILQKAETDPKELQR----IVLAVDVL 1764
+Q+ ++ + L G P P + I+ K DP + + LA++ L
Sbjct: 423 TIQERLLDMLSVVLCGEPFKPLGAPHPNTLTSVPIIPKDAKDPLAYEHRRAEVKLALNTL 482
Query: 1765 GEFYFSRGALQRIMQYVADYYLTADNVEIRLAAVSSCCEMVVPFVGVYKKVTSDKRNSLL 1944
G F FS L ++ VA Y+ ++ EIR AA +CC++ V + + L
Sbjct: 483 GSFDFSGHVLNEFVRDVAIKYVEDEDPEIREAAALTCCQLYVR-----DPIVNQTSYHAL 537
Query: 1945 QTIYGVLRAVCSVIVNDQDVRVRMQVISCFGQMPRPFLAHLAQPEMLEVQFMALHDEKLE 2124
Q + V+ + +V V+D + +R V++ + F HLA+ E + + F AL+DE
Sbjct: 538 QVVGDVIEKLLTVGVSDPEPNIRRTVLAALDER---FDRHLAKAENIRILFFALNDEVFS 594
Query: 2125 MQQACVTLLGRLAELNPAXXXXXXXXXXXXXXSQMQQSGQARLEQHSAKMIAQLAKQSPK 2304
+++ ++++GRLA NPA ++++ S AR ++ SAK+++ L + +
Sbjct: 595 IREVAISIIGRLARYNPAYVIPSLRKTLIQLLTELEFSDVARNKEESAKLLSLLVQNAQS 654
Query: 2305 FMRPYVGSLMIAMIPKLRNDQKYAEVTAQVLNAVSEIAVIGGAEIVKNLKPLFEKLTHMI 2484
++PYV ++ ++PK ++ V A +L A+ E+A +GG +++ L + +
Sbjct: 655 LIKPYVEPMISVLLPKAKDPN--PSVAATILKAIGELATVGGEDMMPYKDRLMPLILDAL 712
Query: 2485 NDSSSLHKREAALRAIGGICRSTAYVVDPYRDYPSLLDDLLRILKTVMSNT-MRREAIKT 2661
D SS KREAAL A+G + ++ YV+ PY +YP LL+ L I++T +R+E IK
Sbjct: 713 QDQSSNAKREAALHALGQLASNSGYVILPYIEYPQLLEILQSIIRTEGQRVPLRQETIKL 772
Query: 2662 LGILGAIDPYTHKVFTGSVQSSTAISTALSLPISETDSKDPRQDIIHWFNYEKCTLEEFY 2841
+GILGA+DPY H+ + S +T L+ DI + +E++
Sbjct: 773 MGILGALDPYKHQAEERTPDSRNGEATQLT-------------DISLMMTGLTPSNKEYF 819
Query: 2842 PAITIANLMLMMQDED-SQSYAEIAQAIVTIFRSLGDMAPLYTEQVIPRLIEVCRRATES 3018
P + I L+ +++D Q +A + +AI+ IFR+LG + +++IP ++V R AT +
Sbjct: 820 PTVVINALLQILKDSSLVQHHAAVIEAIMNIFRTLGLECVSFLDRIIPAFLQVIRSATST 879
Query: 3019 SNRANLREFFLQQLANFVAIIRKHAAPYMPAIFTIIADAWKEDISVKMVVIEVLTDMGTA 3198
E + QLA V+I+R+H Y+P+I I+ + W S++ ++ ++ + +
Sbjct: 880 R-----LESYFNQLATLVSIVRQHIRNYLPSIVEILQEYWHTSPSLQTTILSLVEAISRS 934
Query: 3199 IGNDFSKYTGELIPYLLTVLQTDKTKERVLTVKVMESIQKLTHCIXXXXXXXXXXXXXXX 3378
+ +F Y L+P +L VL D + +R + +VM +
Sbjct: 935 LEGEFKIYLAGLLPLMLGVLDKDNSAKRTPSERVMHAFLVFGASAEEYMHLIIPVIVRTF 994
Query: 3379 XXFSLKLSIRNTALSTVLHMTQQVDVSAYAPRMM 3480
IR A+ T+ +++QV+++ YA +++
Sbjct: 995 EKQGQPTFIRKQAIDTIGKISRQVNLNDYAAKII 1028
Score = 277 bits (709), Expect = 3e-72
Identities = 192/666 (28%), Positives = 312/666 (46%), Gaps = 47/666 (7%)
Frame = +1
Query: 3952 KQRLNKDALMPQWKNENLTSKDEWLQWLMKIRIGFLTYGSSPSLRAASSLGDQHPHLARD 4131
K +N L W + ++K++W +WL + LT + +LRA +SL + LAR+
Sbjct: 1121 KLEMNAIHLKAAWDTKGKSTKEDWQEWLRRFSTTLLTESPNHALRACASLASVYLPLARE 1180
Query: 4132 LFPAAFMSVWTELDSDVQNDLTSCLLRAISTGI--PELIQTILNLAEFMDHSEKGPLPIS 4305
LF +AF+S W+EL Q++L + AI + P+L+ +LNLAEFM+H +K LPI
Sbjct: 1181 LFNSAFVSCWSELYEQFQDELIQNIESAIKSENVPPDLLGLLLNLAEFMEHDDKA-LPID 1239
Query: 4306 HDVLGRWAEQTKAFAKACRYKEMSVLKKSGSMQTTFTRKVKLEPNDCQSLITYANKLNVQ 4485
VLGR A + A+AKA YKE+ L+ S ++LI N+L
Sbjct: 1240 IRVLGREAARCHAYAKALHYKELEFLQDQSS-------------GAVEALIVINNQLQQS 1286
Query: 4486 EEAAGVVRYAERNEMNFQMRGRWYEKLNEWEKALGAYELEEKKKSSCPNLQVYDEKDHLM 4665
+ A G++R A+ + Q+R W+EKL WE+AL Y E++
Sbjct: 1287 DAAIGILRKAQLYKEGIQLRETWFEKLERWEEALAFYNKREEE----------------- 1329
Query: 4666 TPXXXXXXXXXRMHEMRCLEALGRWDELNSKS-VVWADQRGNRNDSVRDEINKKQLDHKM 4842
P M +MRCL ALG W+ L S + WA+ + ++ +
Sbjct: 1330 VPEDQAIPVDIVMGKMRCLHALGEWEALASLTGSTWAN-------------STPEVQRMI 1376
Query: 4843 AVIAARGAWAVDNWERMADYVSVISENTQDGAMLRAVVAVHNDENTKAMGLIEKVREMID 5022
A +A AW ++ W+ M +Y+S + + D + A++A+H ++ +A+ + + RE +D
Sbjct: 1377 APLATAAAWGLNKWDSMDNYLSSLKRYSPDRSFFGAILALHRNQFREAIACVTQAREGLD 1436
Query: 5023 SELTAMANESYERAYIPMVSVQQMAELEEAIEYKTRPERRPRI-ALLWSRRLQGCRRNVE 5199
+EL+A+ +ESY RAY +V VQ +AELEE I YK E++ I W RL+GC+RNVE
Sbjct: 1437 TELSALVSESYNRAYQVVVRVQMLAELEELIVYKQCDEKKQAIMRRTWETRLKGCQRNVE 1496
Query: 5200 QWQRLIMLRGLVLSPQEMHPLRVKFSSMCRKQGKNSMSRAVLRELLSLPA---------N 5352
WQR++ LR +V++P E + +KF+++CRK G+ ++ L++L+ A N
Sbjct: 1497 VWQRMLRLRAIVIAPTENMHMWIKFANLCRKSGRMGLAEKSLKQLIGTDAPLESMIPYWN 1556
Query: 5353 SDLVRAKAPFDKPLLVLALAKQLYQDD---------------------HKDEAIRALEDL 5469
P P + A YQ + ++A + L+
Sbjct: 1557 DQRQPGPGPRSAPAAQVIYAVLKYQWETGQQAAKKTNIPEKTLYCLRKFTNDAAQRLDIT 1616
Query: 5470 ANHWNKRINPIPKATG---------RELIPPSTK----EPARICAKVLLKLGEWTELKSK 5610
H N ++ TG ++ P T+ E + AK L+ GEW L +
Sbjct: 1617 RAHLNAQVGSEVNITGDYGFQNPMDPTIMSPQTQRALYEQTVLLAKCYLRQGEW--LIAL 1674
Query: 5611 TSNNMQVGELSFVRQQVSPQYRTKESRTPETIAFENTINYYQQATQYDPGWHKVWHKLAS 5790
++ Q ++ ++ + Y QAT+Y+P W+K WH A
Sbjct: 1675 NKDDWQYTQV------------------------QDILTSYSQATKYNPRWYKAWHAWAL 1710
Query: 5791 THFYAV 5808
+F V
Sbjct: 1711 ANFEIV 1716