Homology by BLASTX
BLASTX 2.2.4 [Aug-26-2002]
Query= C34G6_4
(3798 letters)
Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
1,967,186 sequences; 661,712,633 total letters
Score E
Sequences producing significant alignments: (bits) Value
gi|17508505|ref|NP_491707.1| P-GlycoProtein related (pgp-2) [Cae... 2373 0.0
gi|25297453|pir||D87789 protein C34G6.4 [imported] - Caenorhabdi... 2359 0.0
gi|39595370|emb|CAE60408.1| Hypothetical protein CBG04013 [Caeno... 2263 0.0
gi|7511698|pir||T31073 multidrug resistance p-glycoprotein - nem... 1673 0.0
gi|6755046|ref|NP_035205.1| ATP-binding cassette, sub-family B (... 1056 0.0
gi|25453370|ref|NP_036755.2| P-glycoprotein/multidrug resistance... 1051 0.0
gi|2506118|sp|P08183|MDR1_HUMAN Multidrug resistance protein 1 (... 1046 0.0
gi|42741659|ref|NP_000918.2| ATP-binding cassette sub-family B m... 1045 0.0
gi|31442763|gb|AAN07780.2| multidrug resistance p-glycoprotein [... 1043 0.0
gi|307180|gb|AAA59575.1| P-glycoprotein [Homo sapiens] 1043 0.0
gi|46394984|gb|AAS91648.1| multidrug resistance protein; P-glyco... 1042 0.0
gi|22775296|gb|AAN07779.1| multidrug resistance p-glycoprotein [... 1040 0.0
gi|2353264|gb|AAB69423.1| P-glycoprotein [Homo sapiens] 1039 0.0
gi|126924|sp|P21448|MDR1_CRIGR Multidrug resistance protein 1 (P... 1039 0.0
gi|46394982|gb|AAS91647.1| multidrug resistance protein 1; P-gly... 1038 0.0
gi|6755048|ref|NP_035206.1| ATP-binding cassette, sub-family B (... 1038 0.0
gi|266517|sp|P21447|MDR3_MOUSE Multidrug resistance protein 3 (P... 1038 0.0
gi|833699|gb|AAA75000.1| multidrug resistance protein >gnl|BL_OR... 1037 0.0
gi|8926217|gb|AAF81747.1| his-tagged-multidrug resistance glycop... 1037 0.0
gi|1362689|pir||S55692 multidrug resistance protein homolog (mdr... 1037 0.0
gi|72477|pir||DVHY1C multidrug resistance protein 1 - Chinese ha... 1036 0.0
gi|126928|sp|P21449|MDR2_CRIGR Multidrug resistance protein 2 (P... 1035 0.0
gi|1170902|sp|P43245|MDR1_RAT Multidrug resistance protein 1 (P-... 1035 0.0
gi|22759019|gb|AAN05645.1| multidrug resistance p-glycoprotein [... 1034 0.0
gi|25453402|ref|NP_596892.1| ATP-binding cassette, sub-family B ... 1033 0.0
gi|2852441|gb|AAC02113.1| multidrug resistance p-glycoprotein [C... 1031 0.0
gi|46394986|gb|AAS91649.1| multidrug resistance protein 1a; P-gl... 1030 0.0
gi|6679297|ref|NP_032856.1| ATP-binding cassette, sub-family B (... 1025 0.0
gi|4505771|ref|NP_000434.1| ATP-binding cassette, subfamily B, m... 1025 0.0
gi|2149087|gb|AAB58489.1| multidrug resistance protein-1 [Ovis a... 1024 0.0
gi|126930|sp|P23174|MDR3_CRIGR Multidrug resistance protein 3 (P... 1024 0.0
gi|9961250|ref|NP_061337.1| ATP-binding cassette, subfamily B, m... 1019 0.0
gi|45382457|ref|NP_990225.1| ABC transporter protein [Gallus gal... 1014 0.0
gi|6981354|ref|NP_036822.1| ATP-binding cassette, sub-family B (... 1013 0.0
gi|48267183|gb|AAQ63650.3| multi-drug resistance P-glycoprotein ... 1008 0.0
gi|191157|gb|AAA37005.1| p-glycoprotein 1004 0.0
gi|40644181|emb|CAC86600.1| multidrug resistance protein [Platic... 1003 0.0
gi|17558664|ref|NP_507487.1| P-GlycoProtein related (pgp-9) [Cae... 992 0.0
gi|39587899|emb|CAE67917.1| Hypothetical protein CBG13514 [Caeno... 988 0.0
gi|39585393|emb|CAE61715.1| Hypothetical protein CBG05664 [Caeno... 987 0.0
gi|50732589|ref|XP_418707.1| PREDICTED: similar to ATP-binding c... 987 0.0
gi|9961252|ref|NP_061338.1| ATP-binding cassette, subfamily B, m... 977 0.0
gi|27656757|gb|AAO20901.1| Mdr3 [Takifugu rubripes] 973 0.0
gi|17541710|ref|NP_502413.1| P-GlycoProtein related (pgp-1) [Cae... 973 0.0
gi|283551|pir||S27337 multidrug resistance protein A - Caenorhab... 972 0.0
gi|72475|pir||DVMS1A multidrug resistance protein 1a - mouse (fr... 957 0.0
gi|6472653|dbj|BAA87071.1| multi-drug resistance related mRNA [F... 956 0.0
gi|45361353|ref|NP_989254.1| hypothetical protein MGC76216 [Xeno... 940 0.0
gi|27656758|gb|AAO20902.1| Mdr2 [Takifugu rubripes] 913 0.0
gi|18496818|gb|AAL74250.1| ABC transporter AbcB3 [Dictyostelium ... 894 0.0
gi|4704820|gb|AAD28285.1| bile salt export pump [Homo sapiens] 885 0.0
gi|21536378|ref|NP_003733.2| ATP-binding cassette, sub-family B ... 884 0.0
gi|14030565|gb|AAK52958.1| bile salt export pump [Raja erinacea] 884 0.0
gi|38073917|ref|XP_283101.2| similar to multidrug resistance p-g... 884 0.0
gi|12643301|sp|O95342|AB11_HUMAN Bile salt export pump (ATP-bind... 883 0.0
gi|17569143|ref|NP_509901.1| P-GlycoProtein related (pgp-3) [Cae... 881 0.0
gi|11038656|ref|NP_066302.1| ATP-binding cassette, sub-family B,... 877 0.0
gi|13929072|ref|NP_113948.1| ATP-binding cassette, sub-family B ... 876 0.0
gi|39594784|emb|CAE70652.1| Hypothetical protein CBG17357 [Caeno... 875 0.0
gi|7514034|pir||T42228 P-glycoprotein sister - rat >gnl|BL_ORD_I... 875 0.0
gi|40644167|emb|CAC86593.1| sister of P-glycoprotein [Platichthy... 872 0.0
gi|31213429|ref|XP_315658.1| ENSANGP00000021663 [Anopheles gambi... 865 0.0
gi|18496816|gb|AAL74249.1| ABC transporter AbcB2 [Dictyostelium ... 864 0.0
gi|283552|pir||S27338 P-glycoprotein C - Caenorhabditis elegans ... 859 0.0
gi|39594783|emb|CAE70651.1| Hypothetical protein CBG17356 [Caeno... 854 0.0
gi|12585141|sp|Q9N0V3|AB11_RABIT Bile salt export pump (ATP-bind... 849 0.0
gi|17569145|ref|NP_509902.1| P-GlycoProtein related (pgp-4) [Cae... 849 0.0
gi|48094917|ref|XP_394305.1| similar to ENSANGP00000021663 [Apis... 838 0.0
gi|27368865|emb|CAD59590.1| MDR-like ABC transporter [Oryza sati... 835 0.0
gi|15228695|ref|NP_191774.1| multidrug resistant (MDR) ABC trans... 826 0.0
gi|22535563|dbj|BAC10738.1| putative multidrug resistance protei... 823 0.0
gi|15226477|ref|NP_182223.1| multidrug resistant (MDR) ABC trans... 823 0.0
gi|27368859|emb|CAD59587.1| MDR-like ABC transporter [Oryza sati... 814 0.0
gi|22026798|ref|NP_523740.2| CG8523-PA [Drosophila melanogaster]... 813 0.0
gi|19032275|dbj|BAB85651.1| multidrug resistance protein 1 homol... 812 0.0
gi|34894326|ref|NP_908488.1| unnamed protein product [Oryza sati... 811 0.0
gi|27368855|emb|CAD59585.1| MDR-like ABC transporter [Oryza sati... 810 0.0
gi|15217785|ref|NP_171753.1| multidrug resistance P-glycoprotein... 810 0.0
gi|34913530|ref|NP_918112.1| putative multidrug resistance prote... 808 0.0
gi|50750485|ref|XP_422016.1| PREDICTED: similar to liver bile sa... 807 0.0
gi|39587988|emb|CAE57219.1| Hypothetical protein CBG00079 [Caeno... 806 0.0
gi|14715462|dbj|BAB62040.1| CjMDR1 [Coptis japonica] 805 0.0
gi|266518|sp|Q00449|MDR4_DROME Multidrug resistance protein homo... 804 0.0
gi|24653245|ref|NP_523724.2| CG3879-PA [Drosophila melanogaster]... 804 0.0
gi|17567269|ref|NP_510128.1| P-GlycoProtein related (146.8 kD) (... 802 0.0
gi|15217786|ref|NP_171754.1| multidrug resistance P-glycoprotein... 802 0.0
gi|39587992|emb|CAE57223.1| Hypothetical protein CBG00086 [Caeno... 796 0.0
gi|157873|gb|AAA16186.1| P-glycoprotein/multidrug resistance pro... 796 0.0
gi|1079107|pir||A47377 multidrug resistance protein Mdr50 - frui... 796 0.0
gi|15237456|ref|NP_199466.1| ABC transporter family protein [Ara... 795 0.0
gi|34911450|ref|NP_917072.1| putative multidrug resistance prote... 794 0.0
gi|25297456|pir||F86155 probable ABC transporter [imported] - Ar... 793 0.0
gi|5456701|gb|AAD43626.1| multidrug resistance protein MDR [Emer... 790 0.0
gi|17567265|ref|NP_510126.1| P-GlycoProtein related (pgp-12) [Ca... 785 0.0
gi|15234323|ref|NP_192092.1| multidrug resistance P-glycoprotein... 784 0.0
gi|13641444|gb|AAK31736.1| p-glycoprotein [Mucor racemosus] 784 0.0
gi|2673951|gb|AAB88657.1| multidrug resistance protein 1 [Asperg... 783 0.0
gi|15234322|ref|NP_192091.1| multidrug resistance P-glycoprotein... 782 0.0
gi|17136662|ref|NP_476831.1| CG10181-PA [Drosophila melanogaster... 781 0.0
gi|25455873|pir||T52319 P-glycoprotein-like protein pgp3 [import... 781 0.0
gi|11346278|pir||T43261 multidrug resistance protein 1 - fungus ... 781 0.0
gi|21464386|gb|AAM51996.1| RE14657p [Drosophila melanogaster] 781 0.0
gi|103252|pir||B41249 multidrug resistance protein homolog Mdr65... 780 0.0
gi|15228506|ref|NP_189528.1| multidrug resistance P-glycoprotein... 780 0.0
gi|24324262|gb|AAN28720.2| MDR-like p-glycoprotein [Arabidopsis ... 779 0.0
gi|49089458|ref|XP_406437.1| hypothetical protein AN2300.2 [Aspe... 778 0.0
gi|50260330|gb|EAL22989.1| hypothetical protein CNBA7570 [Crypto... 777 0.0
gi|26449438|dbj|BAC41846.1| putative P-glycoprotein [Arabidopsis... 776 0.0
gi|22328760|ref|NP_193539.2| ABC transporter family protein [Ara... 776 0.0
gi|46390486|dbj|BAD15946.1| putative MDR-like ABC transporter [O... 775 0.0
gi|34913544|ref|NP_918119.1| putative multidrug resistance prote... 775 0.0
gi|50546639|ref|XP_500789.1| hypothetical protein [Yarrowia lipo... 775 0.0
gi|25407562|pir||H85202 hypothetical protein AT4g18050 [imported... 775 0.0
gi|39587990|emb|CAE57221.1| Hypothetical protein CBG00083 [Caeno... 773 0.0
gi|422285|pir||S30327 multidrug resistance protein 1 - Entamoeba... 766 0.0
gi|422286|pir||S30328 multidrug resistance protein 2 - Entamoeba... 761 0.0
gi|27368849|emb|CAD59582.1| MDR-like ABC transporter [Oryza sati... 761 0.0
gi|27368847|emb|CAD59581.1| MDR-like ABC transporter [Oryza sati... 758 0.0
gi|50543630|ref|XP_499981.1| hypothetical protein [Yarrowia lipo... 757 0.0
gi|15217776|ref|NP_174115.1| multidrug resistance P-glycoprotein... 756 0.0
gi|39587987|emb|CAE57218.1| Hypothetical protein CBG00078 [Caeno... 755 0.0
gi|15147363|gb|AAG01549.3| multidrug resistance protein MDR [Tri... 755 0.0
gi|39594940|emb|CAE70808.1| Hypothetical protein CBG17570 [Caeno... 754 0.0
gi|50556486|ref|XP_505651.1| hypothetical protein [Yarrowia lipo... 754 0.0
gi|393116|gb|AAA93553.1| P-glycoprotein 5 752 0.0
gi|4204793|gb|AAD10836.1| P-glycoprotein [Solanum tuberosum] 751 0.0
gi|17550138|ref|NP_509810.1| P-GlycoProtein related (pgp-5) [Cae... 751 0.0
gi|50507726|emb|CAA94219.3| Hypothetical protein T21E8.2 [Caenor... 750 0.0
gi|15217809|ref|NP_174122.1| multidrug resistance P-glycoprotein... 749 0.0
gi|7494503|pir||T30855 multidrug resistance protein 2 - fluke (S... 748 0.0
gi|24659289|ref|NP_648040.1| CG10226-PA [Drosophila melanogaster... 745 0.0
gi|17569909|ref|NP_509812.1| P-GlycoProtein related (pgp-7) [Cae... 744 0.0
gi|27368861|emb|CAD59588.1| MDR-like ABC transporter [Oryza sati... 742 0.0
gi|15228052|ref|NP_181228.1| multidrug resistance P-glycoprotein... 742 0.0
gi|27368851|emb|CAD59583.1| MDR-like ABC transporter [Oryza sati... 741 0.0
gi|25146777|ref|NP_509811.2| P-GlycoProtein related (pgp-8) [Cae... 739 0.0
gi|7511495|pir||T18940 multidrug resistance protein homolog - Ca... 738 0.0
gi|21740907|emb|CAD40903.1| OSJNBa0036B21.21 [Oryza sativa (japo... 736 0.0
gi|22655312|gb|AAM98246.1| putative ABC transporter [Arabidopsis... 736 0.0
gi|39595964|emb|CAE67467.1| Hypothetical protein CBG12969 [Caeno... 736 0.0
gi|5733124|gb|AAD49436.1| P-glycoprotein [Onchocerca volvulus] 735 0.0
gi|15229473|ref|NP_189475.1| ABC transporter family protein [Ara... 734 0.0
gi|46390962|dbj|BAD16475.1| putative multidrug resistance p-glyc... 733 0.0
gi|7442651|pir||T14805 hypothetical protein F15J5.20 - Arabidops... 731 0.0
gi|39594939|emb|CAE70807.1| Hypothetical protein CBG17569 [Caeno... 730 0.0
gi|6671365|gb|AAF23176.1| P-glycoprotein [Gossypium hirsutum] 729 0.0
gi|15232978|ref|NP_189480.1| P-glycoprotein, putative [Arabidops... 728 0.0
gi|17569907|ref|NP_509813.1| P-GlycoProtein related (pgp-6) [Cae... 728 0.0
gi|9294577|dbj|BAB02858.1| multidrug resistance p-glycoprotein; ... 726 0.0
gi|15220188|ref|NP_172538.1| P-glycoprotein, putative [Arabidops... 726 0.0
gi|38049160|gb|AAR10387.1| P-glycoprotein 1 [Sorghum bicolor] 725 0.0
gi|20466380|gb|AAM20507.1| P-glycoprotein-2 [Arabidopsis thaliana] 724 0.0
gi|15236067|ref|NP_194326.1| multidrug resistance P-glycoprotein... 723 0.0
gi|22331385|ref|NP_683599.1| P-glycoprotein, putative [Arabidops... 721 0.0
gi|9294571|dbj|BAB02852.1| multidrug resistance p-glycoprotein; ... 718 0.0
gi|45735908|dbj|BAD12940.1| putative P-glycoprotein 1 [Oryza sat... 717 0.0
gi|17567271|ref|NP_510129.1| P-GlycoProtein related (pgp-15) [Ca... 717 0.0
gi|15232977|ref|NP_189479.1| P-glycoprotein, putative [Arabidops... 715 0.0
gi|15232975|ref|NP_189477.1| ABC transporter family protein [Ara... 707 0.0
gi|7493911|pir||T30882 multidrug resistance protein 1 - Aspergil... 706 0.0
gi|27368845|emb|CAD59580.1| MDR-like ABC transporter [Oryza sati... 704 0.0
gi|7442649|pir||T06165 multidrug resistance protein 1 homolog - ... 701 0.0
gi|27368839|emb|CAD59577.1| MDR-like ABC transporter [Oryza sati... 698 0.0
gi|4574224|gb|AAD23956.1| multidrug resistance transporter homol... 692 0.0
gi|7494131|pir||T30804 P-glycoprotein 6 - Entamoeba histolytica ... 685 0.0
gi|34910738|ref|NP_916716.1| putative P-glycoprotein [Oryza sati... 682 0.0
gi|24960750|gb|AAN65444.1| Hypothetical protein [Oryza sativa (j... 678 0.0
gi|25297460|pir||B86240 protein F20B24.12 [imported] - Arabidops... 677 0.0
gi|38345252|emb|CAD41096.2| OSJNBb0011N17.13 [Oryza sativa (japo... 677 0.0
gi|27368841|emb|CAD59578.1| MDR-like ABC transporter [Oryza sati... 676 0.0
gi|37695542|gb|AAR00316.1| PGP1; ZMPGP1 [Zea mays] 672 0.0
gi|2360941|gb|AAB69130.1| P-glycoprotein 669 0.0
gi|27368867|emb|CAD59591.1| MDR-like ABC transporter [Oryza sati... 667 0.0
gi|46129276|ref|XP_388999.1| hypothetical protein FG08823.1 [Gib... 667 0.0
gi|159363|gb|AAA02977.1| P-glycoprotein 665 0.0
gi|37806003|dbj|BAC99416.1| putative MDR-like ABC transporter [O... 662 0.0
gi|730011|sp|Q06034|MDR1_LEIEN Multidrug resistance protein 1 (P... 662 0.0
gi|4521245|dbj|BAA76299.1| LAMDR1 [Leishmania mexicana amazonensis] 654 0.0
gi|27368869|emb|CAD59592.1| MDR-like ABC transporter [Oryza sati... 654 0.0
gi|33307712|gb|AAQ03033.1| P-glycoprotein [Homo sapiens] 652 0.0
gi|39594943|emb|CAE70811.1| Hypothetical protein CBG17574 [Caeno... 652 0.0
gi|27368843|emb|CAD59579.1| MDR-like ABC transporter [Oryza sati... 642 0.0
gi|49092568|ref|XP_407745.1| hypothetical protein AN3608.2 [Aspe... 642 0.0
gi|16304396|gb|AAL15148.1| multidrug resistance transporter-like... 640 0.0
gi|7442650|pir||JG0166 LaMDR1 protein - Leishmania mexicana amaz... 640 0.0
gi|38098857|gb|AAR11078.1| ATP binding cassette transporter [Lep... 640 0.0
gi|9294508|dbj|BAB02613.1| P-glycoprotein; multi-drug resistance... 635 e-180
gi|36413607|ref|NP_848654.2| ATP-binding cassette, sub-family B,... 629 e-178
gi|4587971|gb|AAD25925.1| ABC transporter protein AtrC [Emericel... 629 e-178
gi|50732439|ref|XP_418636.1| PREDICTED: similar to Multidrug res... 617 e-175
gi|46109604|ref|XP_381860.1| hypothetical protein FG01684.1 [Gib... 608 e-172
gi|7508148|pir||T25082 hypothetical protein T21E8.2 - Caenorhabd... 607 e-172
gi|33299999|emb|CAA88940.3| Hypothetical protein DH11.3 [Caenorh... 604 e-171
gi|49089656|ref|XP_406486.1| hypothetical protein AN2349.2 [Aspe... 593 e-167
gi|7508147|pir||T25083 hypothetical protein T21E8.1 - Caenorhabd... 588 e-166
gi|49138261|ref|XP_413479.1| hypothetical protein AN9342.2 [Aspe... 587 e-166
gi|5456699|gb|AAD43625.1| ATP-binding cassette multidrug transpo... 585 e-165
gi|46401536|dbj|BAD16632.1| LAMDR2 [Leishmania amazonensis] 578 e-163
gi|46125007|ref|XP_387057.1| hypothetical protein FG06881.1 [Gib... 576 e-162
gi|32400322|dbj|BAC78652.1| ABC transporter [Aspergillus oryzae] 564 e-159
gi|46116988|ref|XP_384512.1| hypothetical protein FG04336.1 [Gib... 563 e-159
gi|32418014|ref|XP_329485.1| hypothetical protein [Neurospora cr... 561 e-158
gi|49084736|ref|XP_404541.1| hypothetical protein AN0404.2 [Aspe... 561 e-158
gi|46114962|ref|XP_383499.1| hypothetical protein FG03323.1 [Gib... 557 e-157
gi|32402932|ref|XP_322079.1| hypothetical protein [Neurospora cr... 554 e-156
gi|45775220|gb|AAK83023.2| truncated P-glycoprotein [Rattus norv... 551 e-155
gi|18033871|gb|AAL57242.1| ATP-binding cassette transporter ABC3... 550 e-154
gi|7522025|pir||T30191 multidrug resistance protein 1 - Aureobas... 548 e-154
gi|49097828|ref|XP_410374.1| hypothetical protein AN6237.2 [Aspe... 548 e-154
gi|46107316|ref|XP_380717.1| hypothetical protein FG00541.1 [Gib... 544 e-153
gi|38101651|gb|EAA48581.1| hypothetical protein MG00239.4 [Magna... 538 e-151
gi|18253111|dbj|BAB83959.1| multidrug resistance p-glycoprotein ... 525 e-147
gi|47225422|emb|CAG11905.1| unnamed protein product [Tetraodon n... 517 e-145
gi|47225423|emb|CAG11906.1| unnamed protein product [Tetraodon n... 498 e-139
gi|72478|pir||DVHY2C multidrug resistance protein 2 - Chinese ha... 494 e-138
gi|4768949|gb|AAD29692.1| sister of P-glycoprotein [Fundulus het... 492 e-137
gi|18124158|gb|AAL59848.1| ATP-binding cassette protein 3 [Crypt... 491 e-137
gi|32399046|emb|CAD98286.1| ATP-binding cassette transporter [Cr... 491 e-137
gi|191159|gb|AAA37006.1| P-glycoprotein (pgp1) 486 e-135
gi|25990364|gb|AAN76500.1| P-glycoprotein [Homo sapiens] 480 e-133
gi|34935680|ref|XP_234725.2| similar to P-glycoprotein [Rattus n... 478 e-133
gi|191153|gb|AAA37003.1| p-glycoprotein 468 e-130
gi|45735907|dbj|BAD12939.1| putative P-glycoprotein 1 [Oryza sat... 467 e-130
gi|38099353|gb|EAA46710.1| hypothetical protein MG09931.4 [Magna... 466 e-129
gi|47212418|emb|CAG12367.1| unnamed protein product [Tetraodon n... 462 e-128
gi|47218631|emb|CAG04960.1| unnamed protein product [Tetraodon n... 460 e-127
gi|38108326|gb|EAA54363.1| hypothetical protein MG02348.4 [Magna... 457 e-127
gi|17567267|ref|NP_510127.1| P-GlycoProtein related (pgp-13) [Ca... 440 e-121
gi|49080124|ref|XP_403624.1| hypothetical protein UM06009.1 [Ust... 422 e-116
gi|18033873|gb|AAL57243.1| ATP-binding cassette transporter ABC4... 419 e-115
gi|34525|emb|CAA29547.1| P-glycoprotein (431 AA) [Homo sapiens] 401 e-110
gi|19075765|ref|NP_588265.1| leptomycin b resistance protein, ab... 400 e-109
gi|218550|dbj|BAA01537.1| pmd1 protein [Schizosaccharomyces pombe] 400 e-109
gi|5733401|gb|AAD49563.1| P-glycoprotein-like protein [Onchocerc... 395 e-108
gi|47900485|gb|AAT39242.1| putative P-glycoprotein [Oryza sativa... 379 e-103
gi|45735909|dbj|BAD12941.1| putative P-glycoprotein 1 [Oryza sat... 375 e-102
gi|46111809|ref|XP_382962.1| hypothetical protein FG02786.1 [Gib... 368 e-100
gi|1174535|gb|AAA86666.1| ATP-binding cassette protein [Fasciola... 363 1e-98
gi|41052996|dbj|BAD07905.1| putative MDR-like ABC transporter [O... 363 2e-98
gi|49081308|ref|XP_404076.1| hypothetical protein UM06461.1 [Ust... 363 2e-98
gi|10241621|emb|CAC09461.1| putative P-glycoprotein [Oryza sativ... 361 6e-98
gi|18875456|gb|AAL74251.2| ABC transporter AbcB4 [Dictyostelium ... 354 1e-95
gi|17532731|ref|NP_495674.1| P-GlycoProtein related (pgp-11) [Ca... 347 1e-93
gi|39587763|emb|CAE67781.1| Hypothetical protein CBG13356 [Caeno... 345 4e-93
gi|19698967|gb|AAL91219.1| P-glycoprotein, putative [Arabidopsis... 342 3e-92
gi|10177549|dbj|BAB10828.1| ABC transporter-like protein [Arabid... 342 5e-92
gi|19335724|gb|AAL85486.1| transporter associated with antigen p... 342 5e-92
gi|22327455|ref|NP_198720.2| ABC transporter (TAP2) [Arabidopsis... 342 5e-92
gi|13346110|gb|AAK19598.1| putative ABC transporter [Sterkiella ... 340 1e-91
gi|21326114|gb|AAM47580.1| putative ABC-transporter-like protein... 338 6e-91
gi|12278525|gb|AAG49002.1| putative ABC transporter [Hordeum vul... 336 2e-90
gi|12061244|gb|AAG45492.1| 36I5.4 [Oryza sativa (japonica cultiv... 336 3e-90
gi|18496654|gb|AAL74186.1| putative ABC transporter [Triticum mo... 336 3e-90
gi|18496655|gb|AAL74187.1| putative ABC transporter [Triticum mo... 334 8e-90
gi|4156146|gb|AAD05023.1| unknown [Homo sapiens] 334 8e-90
gi|12278526|gb|AAG49003.1| putative ABC transporter [Hordeum vul... 330 1e-88
gi|32966961|gb|AAP92331.1| multixenobiotic resistance protein [C... 329 3e-88
gi|17543740|ref|NP_502776.1| HAlF transporter, PGP related (haf-... 328 8e-88
gi|20530737|gb|AAM27211.1| multidrug resistance protein 4 [Asper... 327 1e-87
gi|42820674|emb|CAF31987.1| ABC transporter, putative [Aspergill... 326 2e-87
gi|20453064|gb|AAM19777.1| At2g39480/F12L6.14 [Arabidopsis thali... 326 3e-87
gi|15225474|ref|NP_181480.1| ABC transporter family protein [Ara... 326 3e-87
gi|27368853|emb|CAD59584.1| MDR-like ABC transporter [Oryza sati... 326 3e-87
gi|22974777|ref|ZP_00020923.1| hypothetical protein [Chloroflexu... 325 7e-87
gi|34906082|ref|NP_914388.1| putative P-glycoprotein [Oryza sati... 324 1e-86
gi|18496814|gb|AAL74248.1| ABC transporter AbcB1 [Dictyostelium ... 322 6e-86
gi|15233244|ref|NP_191092.1| ABC transporter family protein [Ara... 320 2e-85
gi|39583384|emb|CAE66359.1| Hypothetical protein CBG11616 [Caeno... 319 4e-85
gi|31216972|ref|XP_316337.1| ENSANGP00000013796 [Anopheles gambi... 318 5e-85
gi|49474685|ref|YP_032727.1| ABC transporter, ATP-binding protei... 318 6e-85
gi|15966528|ref|NP_386881.1| PROBABLE ABC TRANSPORTER ATP-BINDIN... 315 4e-84
gi|34851887|ref|XP_341718.1| similar to ABC transporter [Rattus ... 315 5e-84
gi|49476161|ref|YP_034202.1| ABC transporter, ATP-binding protei... 311 8e-83
gi|17565938|ref|NP_506645.1| HAlF transporter, PGP related (haf-... 311 1e-82
gi|7510080|pir||T31617 hypothetical protein Y50E8A.m - Caenorhab... 311 1e-82
gi|9992887|gb|AAG11416.1| TagA [Dictyostelium discoideum] 311 1e-82
gi|27366635|ref|NP_762162.1| ABC-type multidrug transport system... 310 1e-82
gi|37676347|ref|NP_936743.1| ABC-type multidrug transport system... 310 2e-82
gi|16121675|ref|NP_404988.1| probable transport ATP-binding prot... 309 3e-82
gi|40787796|gb|AAH64930.1| ATP-binding cassette, sub-family B, m... 309 3e-82
gi|24641565|ref|NP_572810.1| CG1824-PA [Drosophila melanogaster]... 309 3e-82
gi|45441025|ref|NP_992564.1| probable transport ATP-binding prot... 309 4e-82
gi|9506367|ref|NP_062425.1| ATP-binding cassette, sub-family B, ... 308 5e-82
gi|9961244|ref|NP_036221.1| ATP-binding cassette, sub-family B, ... 308 5e-82
gi|28900647|ref|NP_800302.1| putative ATP-binding/permease fusio... 308 8e-82
gi|46916508|emb|CAG23273.1| putative ATP-binding/permease fusion... 307 1e-81
gi|34853987|ref|XP_342615.1| similar to RIKEN cDNA 4833412N02 [R... 306 2e-81
gi|1743404|emb|CAB05917.1| transport-associated protein [Salmo s... 305 4e-81
gi|39586807|emb|CAE65850.1| Hypothetical protein CBG10984 [Caeno... 305 7e-81
gi|37525574|ref|NP_928918.1| Probable transport ATP-binding prot... 304 9e-81
gi|27753995|ref|NP_083296.2| RIKEN cDNA 4833412N02 [Mus musculus... 304 1e-80
gi|26339816|dbj|BAC33571.1| unnamed protein product [Mus musculus] 304 1e-80
gi|23502573|ref|NP_698700.1| ABC transporter, ATP binding/permea... 303 2e-80
gi|27452581|gb|AAN71739.1| ABCB9-like TAP-family protein [Petrom... 303 3e-80
gi|45916934|ref|ZP_00195995.2| COG1132: ABC-type multidrug trans... 303 3e-80
gi|34541348|ref|NP_905827.1| ABC transporter, ATP-binding protei... 302 4e-80
gi|17551158|ref|NP_509205.1| P-GlycoProtein related (pgp-10) [Ca... 302 4e-80
gi|42657938|ref|XP_377933.1| similar to MGC76216 protein [Homo s... 301 6e-80
gi|26345292|dbj|BAC36297.1| unnamed protein product [Mus musculus] 301 6e-80
gi|12248755|dbj|BAB20265.1| mono ATP-binding cassette protein [H... 301 6e-80
gi|5823084|gb|AAD53033.1| TAP1 protein [Oncorhynchus mykiss] 301 1e-79
gi|13123950|sp|Q9NUT2|ABC8_HUMAN ATP-binding cassette, sub-famil... 300 2e-79
gi|159372|gb|AAA02976.1| multi drug resistance P-glycoprotein 300 2e-79
gi|17986606|ref|NP_539240.1| PROBABLE TRANSPORT ATP-BINDING PROT... 300 2e-79
gi|6005804|ref|NP_009119.1| ATP-binding cassette, sub-family B, ... 300 2e-79
gi|17533971|ref|NP_495537.1| HAlF transporter, PGP related (haf-... 300 2e-79
gi|16759854|ref|NP_455471.1| probable transport ATP-binding prot... 300 2e-79
gi|39582351|emb|CAE67600.1| Hypothetical protein CBG13145 [Caeno... 299 3e-79
gi|15891205|ref|NP_356877.1| AGR_L_2179p [Agrobacterium tumefaci... 298 5e-79
gi|13473363|ref|NP_104930.1| ABC transporter, ATP-binding protei... 298 7e-79
gi|15800775|ref|NP_286789.1| ATP-binding transport protein; mult... 298 7e-79
gi|21753735|dbj|BAC04392.1| unnamed protein product [Homo sapiens] 298 7e-79
gi|24112322|ref|NP_706832.1| ATP-binding transport protein; mult... 298 9e-79
gi|26246941|ref|NP_752981.1| Probable transport ATP-binding prot... 298 9e-79
gi|7023646|dbj|BAA92038.1| unnamed protein product [Homo sapiens] 296 2e-78
gi|2147880|pir||I48120 P-glycoprotein - Chinese hamster (fragmen... 296 3e-78
gi|23397593|ref|NP_569844.2| CG3156-PA [Drosophila melanogaster]... 295 4e-78
gi|50121481|ref|YP_050648.1| lipid a export ATP-binding/permease... 295 4e-78
gi|50551833|ref|XP_503391.1| hypothetical protein [Yarrowia lipo... 295 7e-78
gi|1743406|emb|CAB05918.1| transport-associated protein [Salmo s... 294 1e-77
gi|49077780|ref|XP_402711.1| hypothetical protein UM05096.1 [Ust... 294 1e-77
gi|15643057|ref|NP_228100.1| ABC transporter, ATP-binding protei... 293 2e-77
gi|39933996|ref|NP_946272.1| ABC transporter, ATP-binding protei... 292 4e-77
gi|39581765|emb|CAE74138.1| Hypothetical protein CBG21809 [Caeno... 292 4e-77
gi|48730042|ref|ZP_00263791.1| COG1132: ABC-type multidrug trans... 292 5e-77
gi|42527766|ref|NP_972864.1| ABC transporter, ATP-binding/permea... 292 5e-77
gi|21673056|ref|NP_661121.1| ABC transporter, ATP-binding protei... 292 5e-77
gi|48892154|ref|ZP_00325566.1| COG1132: ABC-type multidrug trans... 291 6e-77
gi|47575345|ref|ZP_00245380.1| COG1132: ABC-type multidrug trans... 291 8e-77
gi|2119779|pir||S50217 multidrug resistance protein 3 - rat (fra... 291 8e-77
gi|7445902|pir||T13416 hypothetical protein 171D11.2 - fruit fly... 290 2e-76
gi|27376619|ref|NP_768148.1| HlyB/MsbA family ABC transporter [B... 290 2e-76
gi|15616453|ref|NP_244759.1| ABC transporter (ATP-binding protei... 290 2e-76
gi|39997358|ref|NP_953309.1| ABC transporter, ATP-binding protei... 290 2e-76
gi|39579434|emb|CAE74830.1| Hypothetical protein CBG22668 [Caeno... 289 4e-76
gi|30519701|emb|CAD90041.1| putative ATP-binding cassette transp... 289 4e-76
gi|45548045|ref|ZP_00188081.1| COG1132: ABC-type multidrug trans... 289 4e-76
gi|22298505|ref|NP_681752.1| ABC transporter ATP-binding protein... 289 4e-76
gi|2147879|pir||I48119 P-glycoprotein - Chinese hamster (fragmen... 289 4e-76
gi|23127765|ref|ZP_00109628.1| COG1132: ABC-type multidrug trans... 288 5e-76
gi|48850584|ref|ZP_00304826.1| COG1132: ABC-type multidrug trans... 288 7e-76
gi|15808008|ref|NP_285672.1| ABC transporter, ATP-binding protei... 288 9e-76
gi|17509565|ref|NP_490739.1| HAlF transporter, PGP related (haf-... 288 9e-76
gi|23098860|ref|NP_692326.1| ABC transporter ATP-binding protein... 288 9e-76
gi|39580953|emb|CAE72923.1| Hypothetical protein CBG20243 [Caeno... 287 1e-75
gi|23100898|ref|NP_694365.1| ABC transporter ATP-binding protein... 287 2e-75
gi|7511165|pir||T32865 hypothetical protein ZK484.2 - Caenorhabd... 286 3e-75
gi|17511077|ref|NP_491754.1| HAlF transporter, PGP related (90.8... 286 3e-75
gi|18978026|ref|NP_579383.1| hypothetical ABC transporter [Pyroc... 286 3e-75
gi|22971760|ref|ZP_00018688.1| hypothetical protein [Chloroflexu... 285 8e-75
gi|14520516|ref|NP_125991.1| ABC transporter, ATP-binding protei... 285 8e-75
gi|22959359|ref|ZP_00007012.1| COG1132: ABC-type multidrug trans... 285 8e-75
gi|24216393|ref|NP_713874.1| Probable transport ATP-binding prot... 284 1e-74
gi|17561534|ref|NP_506927.1| HAlF transporter, PGP related (haf-... 284 1e-74
gi|30698733|ref|NP_177218.3| ABC transporter (TAP1) [Arabidopsis... 284 1e-74
gi|27452473|gb|AAN71740.1| ABCB9-like TAP-family protein [Petrom... 284 1e-74
gi|31206493|ref|XP_312209.1| ENSANGP00000002692 [Anopheles gambi... 284 1e-74
gi|5823088|gb|AAD53035.1| TAP2B protein [Oncorhynchus mykiss] 283 2e-74
gi|34496280|ref|NP_900495.1| transport ATP-binding protein msbA ... 283 2e-74
gi|45656430|ref|YP_000516.1| ABC transporter, ATP-binding protei... 283 3e-74
gi|17228136|ref|NP_484684.1| ATP-binding protein of ABC transpor... 282 5e-74
gi|48844191|ref|ZP_00298519.1| COG1132: ABC-type multidrug trans... 281 7e-74
gi|37781028|gb|AAP36720.1| transporter associated with antigen p... 281 7e-74
gi|23469088|ref|ZP_00124423.1| COG1132: ABC-type multidrug trans... 281 7e-74
gi|48864170|ref|ZP_00318063.1| COG1132: ABC-type multidrug trans... 281 8e-74
gi|50877523|emb|CAG37363.1| related to ABC-transporter, ATP-bind... 281 1e-73
gi|30248729|ref|NP_840799.1| ABC transporter, fused permease and... 281 1e-73
gi|45506769|ref|ZP_00159120.1| COG1132: ABC-type multidrug trans... 281 1e-73
gi|21242281|ref|NP_641863.1| ABC transporter ATP-binding protein... 281 1e-73
gi|7498268|pir||T20386 hypothetical protein DH11.3 - Caenorhabdi... 280 1e-73
gi|5911326|gb|AAD55753.1| transporter associated with antigen pr... 280 2e-73
gi|2673955|gb|AAB88659.1| multidrug resistance protein 2 [Asperg... 280 2e-73
gi|16330165|ref|NP_440893.1| ABC transporter [Synechocystis sp. ... 280 2e-73
gi|37521898|ref|NP_925275.1| HlyB/MsbA family ABC transporter [G... 280 2e-73
gi|47225421|emb|CAG11904.1| unnamed protein product [Tetraodon n... 280 2e-73
gi|28199828|ref|NP_780142.1| ABC transporter ATP-binding protein... 279 3e-73
gi|29561855|emb|CAD87788.1| SI:dZ262K18.3 (ATP-binding cassette,... 279 3e-73
gi|39580004|emb|CAE56320.1| Hypothetical protein CBG23985 [Caeno... 279 3e-73
gi|23127335|ref|ZP_00109208.1| COG1132: ABC-type multidrug trans... 278 6e-73
gi|18310507|ref|NP_562441.1| probable ABC transporter [Clostridi... 278 6e-73
gi|17228079|ref|NP_484627.1| ATP-binding protein of ABC transpor... 278 6e-73
gi|19704415|ref|NP_603977.1| Export ABC transporter [Fusobacteri... 278 7e-73
gi|23016084|ref|ZP_00055844.1| COG1132: ABC-type multidrug trans... 277 1e-72
gi|24375163|ref|NP_719206.1| ABC transporter, ATP-binding/permea... 277 1e-72
gi|46133688|ref|ZP_00157567.2| COG1132: ABC-type multidrug trans... 277 1e-72
gi|20807317|ref|NP_622488.1| ABC-type multidrug/protein/lipid tr... 277 1e-72
gi|22997178|ref|ZP_00041414.1| COG1132: ABC-type multidrug trans... 277 1e-72
gi|45656478|ref|YP_000564.1| ABC transporter, atp-binding protei... 277 2e-72
gi|21622336|emb|CAD36977.1| probable multidrug resistance protei... 276 2e-72
gi|23125993|ref|ZP_00107905.1| COG2274: ABC-type bacteriocin/lan... 276 2e-72
gi|28211454|ref|NP_782398.1| multidrug resistance ABC transporte... 276 3e-72
gi|9955966|ref|NP_062571.1| ATP-binding cassette, sub-family B (... 276 3e-72
gi|24216329|ref|NP_713810.1| Probable transport ATP-binding prot... 276 3e-72
gi|22995060|ref|ZP_00039543.1| COG1132: ABC-type multidrug trans... 276 3e-72
gi|17229638|ref|NP_486186.1| ATP-binding protein of ABC transpor... 276 4e-72
gi|32563749|ref|NP_871812.1| HAlF transporter, PGP related (haf-... 276 4e-72
gi|46913988|emb|CAG20770.1| putative transport ATP-binding prote... 276 4e-72
gi|18978027|ref|NP_579384.1| hypothetical ABC transporter [Pyroc... 276 4e-72
gi|15839171|ref|NP_299859.1| ABC transporter ATP-binding protein... 276 4e-72
gi|17230168|ref|NP_486716.1| toxin secretion ABC transporter ATP... 275 5e-72
gi|16127504|ref|NP_422068.1| ABC transporter, HlyB/MsbA family [... 275 8e-72
gi|26006275|dbj|BAC41480.1| mKIAA1520 protein [Mus musculus] 274 1e-71
gi|22095457|sp|Q9JJ59|ABC9_MOUSE ATP-binding cassette, sub-famil... 274 1e-71
gi|46192477|ref|ZP_00207293.1| COG1132: ABC-type multidrug trans... 274 1e-71
gi|28869225|ref|NP_791844.1| ABC transporter, ATP-binding/permea... 274 1e-71
gi|11560034|ref|NP_071574.1| TAP-like ABC transporter [Rattus no... 274 1e-71
gi|9845230|ref|NP_063928.1| ATP-binding cassette, sub-family B, ... 274 1e-71
gi|5911322|gb|AAD55751.1| transporter associated with antigen pr... 274 1e-71
gi|17231731|ref|NP_488279.1| toxin secretion ABC transporter ATP... 274 1e-71
gi|46130174|ref|ZP_00164927.2| COG2274: ABC-type bacteriocin/lan... 273 2e-71
gi|47077792|dbj|BAD18770.1| unnamed protein product [Homo sapiens] 273 2e-71
gi|14520515|ref|NP_125990.1| abc transporter atp-binding protein... 273 2e-71
gi|16272034|ref|NP_438233.1| ABC transporter ATP-binding protein... 273 2e-71
gi|39992420|gb|AAH64384.1| ABCB9 protein [Homo sapiens] 273 3e-71
gi|25384933|pir||AC2517 hypothetical protein hlyB [imported] - N... 273 3e-71
gi|15602726|ref|NP_245798.1| MsbA [Pasteurella multocida Pm70] >... 272 4e-71
gi|23127481|ref|ZP_00109350.1| COG1132: ABC-type multidrug trans... 272 4e-71
gi|21230937|ref|NP_636854.1| ABC transporter ATP-binding protein... 272 5e-71
gi|23024543|ref|ZP_00063750.1| COG1132: ABC-type multidrug trans... 272 5e-71
gi|15596310|ref|NP_249804.1| probable ATP-binding/permease fusio... 271 7e-71
gi|32041123|ref|ZP_00138706.1| COG1132: ABC-type multidrug trans... 271 7e-71
gi|48833973|ref|ZP_00290989.1| COG1132: ABC-type multidrug trans... 271 9e-71
gi|50284785|ref|XP_444820.1| unnamed protein product [Candida gl... 271 1e-70
gi|28897756|ref|NP_797361.1| transport ATP-binding protein MsbA ... 271 1e-70
gi|7445809|pir||S72637 hypothetical ABC exporter component A - T... 271 1e-70
gi|33636348|dbj|BAC81752.1| hydrophobic compound transport facto... 271 1e-70
gi|27365418|ref|NP_760946.1| Transport ATP-binding protein MsbA ... 270 1e-70
gi|23129406|ref|ZP_00111233.1| COG2274: ABC-type bacteriocin/lan... 270 1e-70
gi|18124194|gb|AAL59859.1| transporter associated with antigen p... 270 1e-70
gi|29348795|ref|NP_812298.1| ABC transporter, ATP-binding protei... 270 1e-70
gi|42528281|ref|NP_973379.1| ABC transporter, ATP-binding/permea... 270 2e-70
gi|23111716|ref|ZP_00097309.1| COG1132: ABC-type multidrug trans... 270 2e-70
gi|23098861|ref|NP_692327.1| ABC transporter ATP-binding protein... 270 2e-70
gi|33862350|ref|NP_893910.1| ABC transporter, multi drug efflux ... 270 3e-70
gi|16799903|ref|NP_470171.1| similar to ABC transporter (ATP bin... 269 3e-70
gi|14591494|ref|NP_143574.1| ABC transporter ATP-binding protein... 269 3e-70
gi|48771097|ref|ZP_00275440.1| COG1132: ABC-type multidrug trans... 269 3e-70
gi|46119089|ref|ZP_00176074.2| COG1132: ABC-type multidrug trans... 269 3e-70
gi|425474|gb|AAA66476.1| SMDR1 269 4e-70
gi|37521765|ref|NP_925142.1| HlyB/MsbA family ABC transporter [G... 269 4e-70
gi|20808867|ref|NP_624038.1| ABC-type multidrug/protein/lipid tr... 268 6e-70
gi|23126821|ref|ZP_00108705.1| COG2274: ABC-type bacteriocin/lan... 268 6e-70
gi|37680540|ref|NP_935149.1| transport ATP-binding protein MsbA ... 268 6e-70
gi|46396288|sp|Q47908|MSBA_FRANO Lipid A export ATP-binding/perm... 268 7e-70
gi|290801|gb|AAD15237.1| member of super-family of ABC proteins 268 7e-70
gi|48895152|ref|ZP_00328136.1| COG1132: ABC-type multidrug trans... 268 7e-70
gi|15613689|ref|NP_241992.1| ABC transporter (ATP-binding protei... 268 7e-70
gi|48732123|ref|ZP_00265866.1| COG1132: ABC-type multidrug trans... 268 1e-69
gi|25406058|pir||C96730 probable ABC transporter F5A18.21 [impor... 268 1e-69
gi|15894891|ref|NP_348240.1| ABC-type multidrug/protein/lipid tr... 268 1e-69
gi|17232224|ref|NP_488772.1| ATP-binding protein of ABC transpor... 267 1e-69
gi|4321799|gb|AAD15830.1| TAP2 protein [Xenopus laevis] 267 1e-69
gi|23467052|ref|ZP_00122637.1| COG1132: ABC-type multidrug trans... 267 1e-69
gi|32491003|ref|NP_871257.1| msbA [Wigglesworthia glossinidia en... 267 1e-69
gi|31194451|ref|XP_306173.1| ENSANGP00000015516 [Anopheles gambi... 267 2e-69
gi|21397643|ref|NP_653628.1| ABC_tran, ABC transporter [Bacillus... 266 2e-69
gi|49478904|ref|YP_039169.1| multidrug resistance ABC transporte... 266 2e-69
gi|47567391|ref|ZP_00238104.1| ABC transporter, ATP-binding/perm... 266 2e-69
gi|46113651|ref|ZP_00183228.2| COG1132: ABC-type multidrug trans... 266 2e-69
gi|48855758|ref|ZP_00309916.1| COG1132: ABC-type multidrug trans... 266 2e-69
gi|17229106|ref|NP_485654.1| toxin secretion ABC transporter ATP... 266 3e-69
gi|16078496|ref|NP_389315.1| yknU [Bacillus subtilis subsp. subt... 266 3e-69
gi|47094843|ref|ZP_00232457.1| ABC transporter, ATP-binding prot... 266 4e-69
gi|30023215|ref|NP_834846.1| Multidrug resistance ABC transporte... 266 4e-69
gi|30249744|ref|NP_841814.1| ABC transporter, fused permease and... 266 4e-69
gi|45508509|ref|ZP_00160847.1| COG2274: ABC-type bacteriocin/lan... 266 4e-69
gi|47217174|emb|CAG11010.1| unnamed protein product [Tetraodon n... 266 4e-69
gi|19112543|ref|NP_595751.1| putative permease [Schizosaccharomy... 265 5e-69
gi|50085455|ref|YP_046965.1| lipid transport protein, flippase (... 265 5e-69
gi|33152665|ref|NP_874018.1| ABC transporter ATP-binding protein... 265 5e-69
gi|14591493|ref|NP_143573.1| ABC transporter ATP-binding protein... 265 5e-69
gi|26988843|ref|NP_744268.1| ABC efflux transporter, permease/AT... 265 5e-69
gi|2492605|sp|P97998|MDL1_CANAL ATP-dependent permease MDL1 >gnl... 265 5e-69
gi|46440040|gb|EAK99351.1| hypothetical protein CaO19.2615 [Cand... 265 5e-69
gi|46134906|ref|ZP_00158884.2| COG1132: ABC-type multidrug trans... 265 6e-69
gi|15892996|ref|NP_360710.1| multidrug resistance protein [Ricke... 265 6e-69
gi|34581310|ref|ZP_00142790.1| multidrug resistance protein [Ric... 265 6e-69
gi|18310508|ref|NP_562442.1| probable ABC transporter [Clostridi... 265 6e-69
gi|47092044|ref|ZP_00229837.1| ABC transporter, ATP-binding prot... 265 8e-69
gi|46907068|ref|YP_013457.1| ABC transporter, ATP-binding protei... 265 8e-69
gi|46130296|ref|ZP_00165119.2| COG1132: ABC-type multidrug trans... 265 8e-69
gi|48892234|ref|ZP_00325632.1| COG1132: ABC-type multidrug trans... 265 8e-69
gi|525293|emb|CAA53758.1| PGP1 [Trichomonas vaginalis] 265 8e-69
gi|42784331|ref|NP_981578.1| ABC transporter, ATP-binding/permea... 264 1e-68
gi|47570138|ref|ZP_00240795.1| ABC transporter, ATP-binding/perm... 264 1e-68
gi|37524635|ref|NP_927979.1| hypothetical protein [Photorhabdus ... 264 1e-68
gi|33864729|ref|NP_896288.1| putative multidrug efflux ABC trans... 264 1e-68
gi|34906862|ref|NP_914778.1| putative ABC transporter [Oryza sat... 264 1e-68
gi|23098687|ref|NP_692153.1| ABC transporter ATP-binding protein... 264 1e-68
gi|33861384|ref|NP_892945.1| ABC transporter, possibly multidrug... 264 1e-68
gi|48824040|ref|ZP_00285472.1| COG1132: ABC-type multidrug trans... 263 2e-68
gi|8176565|dbj|BAA96370.1| ABC protein [Physarum polycephalum] 263 2e-68
gi|23113832|ref|ZP_00099175.1| COG1132: ABC-type multidrug trans... 263 2e-68
gi|24374337|ref|NP_718380.1| ABC transporter, ATP-binding protei... 263 2e-68
gi|7445810|pir||S72638 hypothetical ABC exporter component B - T... 263 2e-68
gi|48895639|ref|ZP_00328623.1| COG2274: ABC-type bacteriocin/lan... 263 2e-68
gi|33602558|ref|NP_890118.1| putative ABC transporter [Bordetell... 263 2e-68
gi|15889041|ref|NP_354722.1| AGR_C_3190p [Agrobacterium tumefaci... 263 2e-68
gi|16330857|ref|NP_441585.1| HlyB family [Synechocystis sp. PCC ... 263 2e-68
gi|17935631|ref|NP_532421.1| ABC transporter, nucleotide binding... 263 2e-68
>gi|17508505|ref|NP_491707.1| P-GlycoProtein related (pgp-2)
[Caenorhabditis elegans]
gi|15617726|gb|AAB52482.2| P-glycoprotein related protein 2
[Caenorhabditis elegans]
Length = 1265
Score = 2373 bits (6149), Expect = 0.0
Identities = 1204/1265 (95%), Positives = 1204/1265 (95%)
Frame = +1
Query: 1 MKSRKNEPTWVTKPLLKRXXXXXXXXXXXTVKLTNYGIFYYTQGVDLLLLITGTVAAVIH 180
MKSRKNEPTWVTKPLLKR TVKLTNYGIFYYTQGVDLLLLITGTVAAVIH
Sbjct: 1 MKSRKNEPTWVTKPLLKRSHSSDSSIDESTVKLTNYGIFYYTQGVDLLLLITGTVAAVIH 60
Query: 181 GAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEVVKYCIYYLVL 360
GAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEVVKYCIYYLVL
Sbjct: 61 GAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEVVKYCIYYLVL 120
Query: 361 GVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTARLTDDLER 540
GVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTARLTDDLER
Sbjct: 121 GVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTARLTDDLER 180
Query: 541 VREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTR 720
VREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTR
Sbjct: 181 VREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTR 240
Query: 721 VEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVGF 900
VEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVGF
Sbjct: 241 VEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVGF 300
Query: 901 SNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARG 1080
SNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARG
Sbjct: 301 SNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARG 360
Query: 1081 AASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAG 1260
AASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAG
Sbjct: 361 AASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAG 420
Query: 1261 DKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLF 1440
DKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLF
Sbjct: 421 DKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLF 480
Query: 1441 DGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIA 1620
DGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIA
Sbjct: 481 DGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIA 540
Query: 1621 IARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFV 1800
IARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFV
Sbjct: 541 IARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFV 600
Query: 1801 FKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXXEAGKDIEDTISESAHSHLXXXXXX 1980
FKAGNIVESGSHEELMSKQGIFYDMT EAGKDIEDTISESAHSHL
Sbjct: 601 FKAGNIVESGSHEELMSKQGIFYDMTQAQVVRQQQQEAGKDIEDTISESAHSHLSRKSST 660
Query: 1981 XXXXXXXXXIHQLAEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFAL 2160
IHQLAEEVEECKAPPTSMFKIFKFNGDKVGW SVTPVFAL
Sbjct: 661 RSAISIATSIHQLAEEVEECKAPPTSMFKIFKFNGDKVGWFIGGIFGAFIFGSVTPVFAL 720
Query: 2161 VYAEIFNVYSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEA 2340
VYAEIFNVYSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEA
Sbjct: 721 VYAEIFNVYSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEA 780
Query: 2341 FKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVFTRLPVVLASIVTICGALGIGFYY 2520
FKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVFTRLPVVLASIVTICGALGIGFYY
Sbjct: 781 FKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVFTRLPVVLASIVTICGALGIGFYY 840
Query: 2521 GWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQ 2700
GWQ MGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQ
Sbjct: 841 GWQLALILVVMVPLLVMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQ 900
Query: 2701 EQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPID 2880
EQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPID
Sbjct: 901 EQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPID 960
Query: 2881 VYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGN 3060
VYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGN
Sbjct: 961 VYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGN 1020
Query: 3061 ISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMI 3240
ISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMI
Sbjct: 1021 ISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMI 1080
Query: 3241 MIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIH 3420
MIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIH
Sbjct: 1081 MIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIH 1140
Query: 3421 NFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQ 3600
NFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQ
Sbjct: 1141 NFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQ 1200
Query: 3601 EALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQR 3780
EALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQR
Sbjct: 1201 EALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQR 1260
Query: 3781 IVESQ 3795
IVESQ
Sbjct: 1261 IVESQ 1265
>gi|25297453|pir||D87789 protein C34G6.4 [imported] - Caenorhabditis
elegans
Length = 1289
Score = 2359 bits (6114), Expect = 0.0
Identities = 1204/1289 (93%), Positives = 1204/1289 (93%), Gaps = 24/1289 (1%)
Frame = +1
Query: 1 MKSRKNEPTWVTKPLLKRXXXXXXXXXXXTVKLTNYGIFYYTQGVDLLLLITGTVAAVIH 180
MKSRKNEPTWVTKPLLKR TVKLTNYGIFYYTQGVDLLLLITGTVAAVIH
Sbjct: 1 MKSRKNEPTWVTKPLLKRSHSSDSSIDESTVKLTNYGIFYYTQGVDLLLLITGTVAAVIH 60
Query: 181 GAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEVVKYCIYYLVL 360
GAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEVVKYCIYYLVL
Sbjct: 61 GAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEVVKYCIYYLVL 120
Query: 361 GVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTARLTDDLER 540
GVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTARLTDDLER
Sbjct: 121 GVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTARLTDDLER 180
Query: 541 VREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTR 720
VREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTR
Sbjct: 181 VREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTR 240
Query: 721 VEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVGF 900
VEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVGF
Sbjct: 241 VEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVGF 300
Query: 901 SNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARG 1080
SNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARG
Sbjct: 301 SNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARG 360
Query: 1081 AASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAG 1260
AASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAG
Sbjct: 361 AASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAG 420
Query: 1261 DKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLF 1440
DKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLF
Sbjct: 421 DKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLF 480
Query: 1441 DGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIA 1620
DGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIA
Sbjct: 481 DGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIA 540
Query: 1621 IARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFV 1800
IARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFV
Sbjct: 541 IARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFV 600
Query: 1801 FKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXXEAGKDIEDTISESAHSHLXXXXXX 1980
FKAGNIVESGSHEELMSKQGIFYDMT EAGKDIEDTISESAHSHL
Sbjct: 601 FKAGNIVESGSHEELMSKQGIFYDMTQAQVVRQQQQEAGKDIEDTISESAHSHLSRKSST 660
Query: 1981 XXXXXXXXXIHQLAEEVE------------------------ECKAPPTSMFKIFKFNGD 2088
IHQLAEEVE ECKAPPTSMFKIFKFNGD
Sbjct: 661 RSAISIATSIHQLAEEVELIDPFNGQTNQDVIRSRILSAFGGECKAPPTSMFKIFKFNGD 720
Query: 2089 KVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANVYFWCGMFVLMGITFFV 2268
KVGW SVTPVFALVYAEIFNVYSLPADQMQANVYFWCGMFVLMGITFFV
Sbjct: 721 KVGWFIGGIFGAFIFGSVTPVFALVYAEIFNVYSLPADQMQANVYFWCGMFVLMGITFFV 780
Query: 2269 GFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYV 2448
GFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYV
Sbjct: 781 GFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYV 840
Query: 2449 FTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQL 2628
FTRLPVVLASIVTICGALGIGFYYGWQ MGGYFEMQMRFGKQIRDTQL
Sbjct: 841 FTRLPVVLASIVTICGALGIGFYYGWQLALILVVMVPLLVMGGYFEMQMRFGKQIRDTQL 900
Query: 2629 LEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLI 2808
LEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLI
Sbjct: 901 LEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLI 960
Query: 2809 FFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLF 2988
FFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLF
Sbjct: 961 FFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLF 1020
Query: 2989 YLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVG 3168
YLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVG
Sbjct: 1021 YLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVG 1080
Query: 3169 HSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGEN 3348
HSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGEN
Sbjct: 1081 HSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGEN 1140
Query: 3349 ICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALV 3528
ICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALV
Sbjct: 1141 ICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALV 1200
Query: 3529 RSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKI 3708
RSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKI
Sbjct: 1201 RSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKI 1260
Query: 3709 VEKGTHDELIRKSEIYQKFCETQRIVESQ 3795
VEKGTHDELIRKSEIYQKFCETQRIVESQ
Sbjct: 1261 VEKGTHDELIRKSEIYQKFCETQRIVESQ 1289
>gi|39595370|emb|CAE60408.1| Hypothetical protein CBG04013
[Caenorhabditis briggsae]
Length = 1265
Score = 2263 bits (5864), Expect = 0.0
Identities = 1137/1265 (89%), Positives = 1177/1265 (92%)
Frame = +1
Query: 1 MKSRKNEPTWVTKPLLKRXXXXXXXXXXXTVKLTNYGIFYYTQGVDLLLLITGTVAAVIH 180
MKSRKNEPTWVTKPLLKR TVKLTNYG+F YT+G DL+LLI GT+AAVIH
Sbjct: 1 MKSRKNEPTWVTKPLLKRSHSSDSSIDESTVKLTNYGLFSYTRGKDLILLIVGTIAAVIH 60
Query: 181 GAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEVVKYCIYYLVL 360
GAGFPLLAIVLGGMTTVFLRAQNSDFVVGV NVNP GL PIS+DEFNSEVVKYCIYYL+L
Sbjct: 61 GAGFPLLAIVLGGMTTVFLRAQNSDFVVGVGNVNPNGLEPISIDEFNSEVVKYCIYYLIL 120
Query: 361 GVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTARLTDDLER 540
GV MF TSYVQIACFESYAE LVHKLRQNYLKAILRQQIQWFDKQQTGNLTARLTDDLER
Sbjct: 121 GVAMFVTSYVQIACFESYAENLVHKLRQNYLKAILRQQIQWFDKQQTGNLTARLTDDLER 180
Query: 541 VREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTR 720
VREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRT+
Sbjct: 181 VREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTK 240
Query: 721 VEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVGF 900
VEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRF+NALE GR+TGIVKYCYMGIGVGF
Sbjct: 241 VEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFWNALENGRKTGIVKYCYMGIGVGF 300
Query: 901 SNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARG 1080
SNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARG
Sbjct: 301 SNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARG 360
Query: 1081 AASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAG 1260
AA TVLRVINSHPKIDPYSLEG+LVDNMKGDISF++VHFRYPSRKDI VLKGISLE+K+G
Sbjct: 361 AAYTVLRVINSHPKIDPYSLEGLLVDNMKGDISFQNVHFRYPSRKDIPVLKGISLEVKSG 420
Query: 1261 DKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLF 1440
+KIALVGSSGCGKSTIVNLLQRFYDPTKG+V IDGVDL+E+NVHSLREQIGIVSQEPVLF
Sbjct: 421 EKIALVGSSGCGKSTIVNLLQRFYDPTKGKVSIDGVDLKEINVHSLREQIGIVSQEPVLF 480
Query: 1441 DGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIA 1620
DGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIA
Sbjct: 481 DGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIA 540
Query: 1621 IARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFV 1800
IARALVKNPKILLLDEATSALDTEAEREVQ ALDQAQAGRTT+IVAHRLSTIRNVD+IFV
Sbjct: 541 IARALVKNPKILLLDEATSALDTEAEREVQAALDQAQAGRTTLIVAHRLSTIRNVDKIFV 600
Query: 1801 FKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXXEAGKDIEDTISESAHSHLXXXXXX 1980
FKAGNIVE+GSHEELM+KQG+FYDMT EAGKDIEDTISESAHSHL
Sbjct: 601 FKAGNIVETGSHEELMNKQGVFYDMTQAQVVRQQQQEAGKDIEDTISESAHSHLSRKSST 660
Query: 1981 XXXXXXXXXIHQLAEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFAL 2160
IHQLAEEVEECKAPPT + KIF FN DK+ W SVTPVFAL
Sbjct: 661 RSAISMATSIHQLAEEVEECKAPPTPISKIFNFNRDKIWWFIGGMFGAFIFGSVTPVFAL 720
Query: 2161 VYAEIFNVYSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEA 2340
VYAEIFNVYS P +QMQ++VYFWCGMFVLMGITFF+GFF SANCLGRCGESLTMKLRFEA
Sbjct: 721 VYAEIFNVYSEPVEQMQSDVYFWCGMFVLMGITFFIGFFISANCLGRCGESLTMKLRFEA 780
Query: 2341 FKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVFTRLPVVLASIVTICGALGIGFYY 2520
FKNL+RQDIAFYDDLRHGTGKLCTRFATDAPNVRYVFTRLPVVLASIVTI GALGIGFYY
Sbjct: 781 FKNLMRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVFTRLPVVLASIVTILGALGIGFYY 840
Query: 2521 GWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQ 2700
GWQ MGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQ
Sbjct: 841 GWQLALILVVMVPLLVMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQ 900
Query: 2701 EQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPID 2880
EQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYA AFYLGSIFVNQ +MQPID
Sbjct: 901 EQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAVAFYLGSIFVNQHSMQPID 960
Query: 2881 VYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGN 3060
VYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLS++GIVKPITGN
Sbjct: 961 VYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSEAGIVKPITGN 1020
Query: 3061 ISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMI 3240
ISIRN+FFNYPTRK+TKVLQGFT+DIK G+TVALVGHSGCGKSTIMGLLERFYNQDKGMI
Sbjct: 1021 ISIRNIFFNYPTRKETKVLQGFTIDIKPGQTVALVGHSGCGKSTIMGLLERFYNQDKGMI 1080
Query: 3241 MIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIH 3420
MIDGDNIRNLNISSLR+QVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIH
Sbjct: 1081 MIDGDNIRNLNISSLRQQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIH 1140
Query: 3421 NFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQ 3600
NFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQ
Sbjct: 1141 NFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQ 1200
Query: 3601 EALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQR 3780
EALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIV+KGTHDEL+RKSEIYQK CETQR
Sbjct: 1201 EALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVDKGTHDELMRKSEIYQKLCETQR 1260
Query: 3781 IVESQ 3795
IVESQ
Sbjct: 1261 IVESQ 1265
>gi|7511698|pir||T31073 multidrug resistance p-glycoprotein - nematode
(Haemonchus contortus)
gi|3057042|gb|AAC38987.1| P-glycoprotein [Haemonchus contortus]
Length = 1275
Score = 1673 bits (4333), Expect = 0.0
Identities = 835/1242 (67%), Positives = 1000/1242 (80%), Gaps = 9/1242 (0%)
Frame = +1
Query: 97 LTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDN 276
+TN GI +D +LL GT+A +HGAGF +L IVLGGMTTVFLRAQNS+FV+G +
Sbjct: 34 ITNRGILSLATTLDYVLLAAGTLAPCVHGAGFSVLGIVLGGMTTVFLRAQNSEFVLGTVS 93
Query: 277 VNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLK 456
+PEGL ++ +EF++ V +YC+YYL LG MF TSY+QI C+E++AER+ HKLR+ YLK
Sbjct: 94 RDPEGLPALTKEEFDTLVRRYCLYYLGLGFAMFATSYIQIVCWETFAERITHKLRKIYLK 153
Query: 457 AILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWS 636
AILRQQI WFD QQTGNLTARLTDDLERVREGLGDK +L +QM +AF+AG+ VGF YSWS
Sbjct: 154 AILRQQISWFDIQQTGNLTARLTDDLERVREGLGDKLSLFIQMVSAFVAGFCVGFAYSWS 213
Query: 637 MTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRE 816
MTLVMM AP IV+S MSK +ATRT+VEQETYAVAGAIAEETFSSIRTVHS+ GHKRE
Sbjct: 214 MTLVMMVVAPFIVISANWMSKIVATRTQVEQETYAVAGAIAEETFSSIRTVHSICGHKRE 273
Query: 817 LDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIF 996
L RF ALE GRQTG+VKY YMG+GVGF +C Y SYALAFWYGS LIINDP DRG IF
Sbjct: 274 LTRFEAALEKGRQTGLVKYFYMGVGVGFGQMCTYVSYALAFWYGSVLIINDPALDRGRIF 333
Query: 997 TVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDI 1176
TVFFAV+SGS +LG LPHL + ARGA +VL VINS PKIDPYSL+GI+++NM+G I
Sbjct: 334 TVFFAVMSGSAALGTCLPHLNTISIARGAVRSVLSVINSRPKIDPYSLDGIVLNNMRGSI 393
Query: 1177 SFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVL 1356
FK+VHF YPSR+ + +LKG+SL++ AG KIALVGSSGCGKST VNLL RFYDPT+G+V
Sbjct: 394 RFKNVHFSYPSRRTLQILKGVSLQVSAGQKIALVGSSGCGKSTNVNLLLRFYDPTRGKVT 453
Query: 1357 IDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDF 1536
ID +D+ ++NV LREQIG+VSQEPVLFDGT++ENIKMG E AT ++V EAC++ANA DF
Sbjct: 454 IDDIDVCDLNVQKLREQIGVVSQEPVLFDGTLFENIKMGYEQATMEEVQEACRVANAADF 513
Query: 1537 IKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGA 1716
KRLP+GYGTRVGE+GVQLSGGQKQRIAIARA++KNP+ILLLDEATSALDTEAE VQ A
Sbjct: 514 TKRLPEGYGTRVGERGVQLSGGQKQRIAIARAIIKNPRILLLDEATSALDTEAESIVQEA 573
Query: 1717 LDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXX 1896
L++AQ GRTT+IVAHRLSTIRNVD+IFVFK G IVE G+H ELM+K+G+F++MT
Sbjct: 574 LEKAQKGRTTVIVAHRLSTIRNVDQIFVFKNGTIVEQGTHAELMNKRGVFFEMTQAQVLR 633
Query: 1897 XXXXEAGKDIE---DTIS-ESAHSHLXX----XXXXXXXXXXXXXIHQLAEEVEECKAPP 2052
E D + D +S + A HL + + E+E+ +A P
Sbjct: 634 QEKEEEVLDSDAESDVVSPDIALPHLSSLRSRKESTRSAISAVPSVRSMQIEMEDLRAKP 693
Query: 2053 TSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANVYFWC 2232
T M KIF FN DK G+ +VTP FA++YA+I VYS P DQM+ +V FWC
Sbjct: 694 TPMSKIFYFNRDKWGYFILGLIACIITGTVTPTFAVLYAQIIQVYSEPVDQMKGHVLFWC 753
Query: 2233 GMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCT 2412
G F+++G+ FF SA CLGRCGE+LT KLRFEAFKNLLRQ++ FYDD+RHGTGKLCT
Sbjct: 754 GAFIVIGLVHAFAFFFSAICLGRCGEALTKKLRFEAFKNLLRQNVGFYDDIRHGTGKLCT 813
Query: 2413 RFATDAPNVRYVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQ 2592
RFATDAPNVRYVFTRLP VL+S+VTI GAL IGF +GWQ GYFEM+
Sbjct: 814 RFATDAPNVRYVFTRLPGVLSSVVTIIGALVIGFIFGWQLALILMVMVPLIIGSGYFEMR 873
Query: 2593 MRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHT 2772
M+FGK++RDT+LLEEAGKVASQAVE+IRTVH+LNRQEQFHF YCEYL+EP+ NL AHT
Sbjct: 874 MQFGKKMRDTELLEEAGKVASQAVENIRTVHALNRQEQFHFMYCEYLKEPYRENLCQAHT 933
Query: 2773 YGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPD 2952
YG VFAFSQSL+FFMYA AF++G+IFV+ +MQPIDVYRVFFA FCGQM+GN +SFIPD
Sbjct: 934 YGGVFAFSQSLLFFMYAVAFWIGAIFVDNHSMQPIDVYRVFFAFMFCGQMVGNISSFIPD 993
Query: 2953 VVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTL 3132
VVKARLAASLLFYLIEHP+ ID+LS+ G+ K I+G+IS RNV+FNYPTR+ +VL+G L
Sbjct: 994 VVKARLAASLLFYLIEHPSEIDNLSEDGVTKKISGHISFRNVYFNYPTRRQIRVLRGLNL 1053
Query: 3133 DIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQ 3312
+I G TVALVG SGCGKST+M LLERFYNQ+KG+I +DG+NIRN+NI +LREQVCIVSQ
Sbjct: 1054 EINPGTTVALVGQSGCGKSTVMALLERFYNQNKGVITVDGENIRNMNIRNLREQVCIVSQ 1113
Query: 3313 EPTLFDCTIGENICYG-TNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSG 3489
EPTLFDCTI ENICYG + +Y+++V AAKMANIHNF+LGLP+GYDT VGEKGTQLSG
Sbjct: 1114 EPTLFDCTIMENICYGLDDPKPSYEQVVAAAKMANIHNFVLGLPEGYDTRVGEKGTQLSG 1173
Query: 3490 GQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQ 3669
GQKQRIAIARAL+R P +LLLDEATSALDTESEKIVQ+AL+ A+QGRTCLVIAHRLSTIQ
Sbjct: 1174 GQKQRIAIARALIRDPPILLLDEATSALDTESEKIVQDALEVARQGRTCLVIAHRLSTIQ 1233
Query: 3670 NSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRIVESQ 3795
+SDVI ++ EGK ++GTH+ L+ K+++Y++ CETQR+VESQ
Sbjct: 1234 DSDVIVMIQEGKATDRGTHEHLLMKNDLYKRLCETQRLVESQ 1275
>gi|6755046|ref|NP_035205.1| ATP-binding cassette, sub-family B
(MDR/TAP), member 1B; P glycoprotein 1 [Mus musculus]
gi|126927|sp|P06795|MDR1_MOUSE Multidrug resistance protein 1
(P-glycoprotein 1)
gi|72474|pir||DVMS1 multidrug resistance protein 1 - mouse
gi|387426|gb|AAA79005.1| multidrug resistance protein
Length = 1276
Score = 1056 bits (2730), Expect = 0.0
Identities = 557/1232 (45%), Positives = 788/1232 (63%), Gaps = 15/1232 (1%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNP 285
+G+F Y +D L +I GT+AA+IHG PLL +V G MT F +A+ S + P
Sbjct: 36 FGMFRYADWLDKLCMILGTLAAIIHGTLLPLLMLVFGNMTDSFTKAEASILPSITNQSGP 95
Query: 286 EGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAIL 465
+ IS E+ Y YY +G + +Y+Q++ + A R +HK+RQ + AI+
Sbjct: 96 NSTLIISNSSLEEEMAIYAYYYTGIGAGVLIVAYIQVSLWCLAAGRQIHKIRQKFFHAIM 155
Query: 466 RQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTL 645
Q+I WFD G L RLTDD+ ++ +G+GDK + Q FLAG+ +GF W +TL
Sbjct: 156 NQEIGWFDVHDVGELNTRLTDDVSKINDGIGDKIGMFFQSITTFLAGFIIGFISGWKLTL 215
Query: 646 VMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDR 825
V++ +PLI LS A +K + + T E + YA AGA+AEE ++IRTV + G ++EL+R
Sbjct: 216 VILAVSPLIGLSSALWAKVLTSFTNKELQAYAKAGAVAEEVLAAIRTVIAFGGQQKELER 275
Query: 826 FYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVF 1005
+ LE + GI K I +G + L +Y+SYALAFWYG++L++++ + G + TVF
Sbjct: 276 YNKNLEEAKNVGIKKAITASISIGIAYLLVYASYALAFWYGTSLVLSNE-YSIGEVLTVF 334
Query: 1006 FAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFK 1185
F++L G+ S+G P++ +F ARGAA + ++I++ P ID +S +G D++ G++ FK
Sbjct: 335 FSILLGTFSIGHLAPNIEAFANARGAAFEIFKIIDNEPSIDSFSTKGYKPDSIMGNLEFK 394
Query: 1186 DVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDG 1365
+VHF YPSR ++ +LKG++L++K+G +ALVG+SGCGKST V L+QR YDP +G V IDG
Sbjct: 395 NVHFNYPSRSEVQILKGLNLKVKSGQTVALVGNSGCGKSTTVQLMQRLYDPLEGVVSIDG 454
Query: 1366 VDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKR 1545
D+R +NV LRE IG+VSQEPVLF TI ENI+ G E T D++ +A K ANA DFI +
Sbjct: 455 QDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGREDVTMDEIEKAVKEANAYDFIMK 514
Query: 1546 LPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQ 1725
LP + T VGE+G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E VQ ALD+
Sbjct: 515 LPHQFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDK 574
Query: 1726 AQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXX----- 1890
A+ GRTTI++AHRLST+RN D I F G IVE G+H+ELM ++GI++ +
Sbjct: 575 AREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHDELMREKGIYFKLVMTQTRGNEI 634
Query: 1891 ---XXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLA-EEVEECKAPPTS 2058
++ D + SE + S L +L+ +E + P S
Sbjct: 635 EPGNNAYGSQSDTDASELTSEESKSPLIRRSIYRSVHRKQDQERRLSMKEAVDEDVPLVS 694
Query: 2059 MFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQ--MQANVYFWC 2232
++I N + + + PVFA+V++ I V+S D + N +
Sbjct: 695 FWRILNLNLSEWPYLLVGVLCAVINGCIQPVFAIVFSRIVGVFSRDDDHETKRQNCNLFS 754
Query: 2233 GMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCT 2412
F++MG+ FV +F G+ GE LT ++R+ FK++LRQDI+++DD ++ TG L T
Sbjct: 755 LFFLVMGLISFVTYFFQGFTFGKAGEILTKRVRYMVFKSMLRQDISWFDDHKNSTGSLTT 814
Query: 2413 RFATDAPNVRYVF-TRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEM 2589
R A+DA +V+ RL VV ++ + + + YGWQ +GG EM
Sbjct: 815 RLASDASSVKGAMGARLAVVTQNVANLGTGVILSLVYGWQLTLLLVVIIPLIVLGGIIEM 874
Query: 2590 QMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAH 2769
++ G+ ++D + LE +GK+A++A+E+ RT+ SL R+++F Y + L+ P+ +K AH
Sbjct: 875 KLLSGQALKDKKQLEISGKIATEAIENFRTIVSLTREQKFETMYAQSLQVPYRNAMKKAH 934
Query: 2770 TYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIP 2949
+G F+F+Q++++F YAA F G+ V QQ M +V VF A+ F GNT+SF P
Sbjct: 935 VFGITFSFTQAMMYFSYAACFRFGAYLVAQQLMTFENVMLVFSAVVFGAMAAGNTSSFAP 994
Query: 2950 DVVKARLAASLLFYLIEHPTPIDSLSDSGIVKP--ITGNISIRNVFFNYPTRKDTKVLQG 3123
D KA+++AS + +IE IDS S G+ KP + GN+ V FNYPTR + VLQG
Sbjct: 995 DYAKAKVSASHIIRIIEKTPEIDSYSTEGL-KPTLLEGNVKFNGVQFNYPTRPNIPVLQG 1053
Query: 3124 FTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCI 3303
+L++K G+T+ALVG SGCGKST++ LLERFY+ G + +DG I+ LN+ LR + I
Sbjct: 1054 LSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSVFLDGKEIKQLNVQWLRAHLGI 1113
Query: 3304 VSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQ 3480
VSQEP LFDC+I ENI YG N R V+++EIV AAK ANIH FI LPD Y+T VG+KGTQ
Sbjct: 1114 VSQEPILFDCSIAENIAYGDNSRAVSHEEIVRAAKEANIHQFIDSLPDKYNTRVGDKGTQ 1173
Query: 3481 LSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLS 3660
LSGGQKQRIAIARALVR P +LLLDEATSALDTESEK+VQEALD A++GRTC+VIAHRLS
Sbjct: 1174 LSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLS 1233
Query: 3661 TIQNSDVIAIVSEGKIVEKGTHDELIRKSEIY 3756
TIQN+D+I ++ GK+ E GTH +L+ + IY
Sbjct: 1234 TIQNADLIVVIENGKVKEHGTHQQLLAQKGIY 1265
Score = 428 bits (1100), Expect = e-118
Identities = 240/581 (41%), Positives = 350/581 (59%), Gaps = 5/581 (0%)
Frame = +1
Query: 148 LITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSE 327
L+ G + AVI+G P+ AIV + VF R + D N N
Sbjct: 709 LLVGVLCAVINGCIQPVFAIVFSRIVGVFSR--DDDHETKRQNCN--------------- 751
Query: 328 VVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD--KQQT 501
+ +++LV+G++ F T + Q F E L ++R K++LRQ I WFD K T
Sbjct: 752 --LFSLFFLVMGLISFVTYFFQGFTFGKAGEILTKRVRYMVFKSMLRQDISWFDDHKNST 809
Query: 502 GNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLS 681
G+LT RL D V+ +G + A++ Q A G + Y W +TL+++ PLIVL
Sbjct: 810 GSLTTRLASDASSVKGAMGARLAVVTQNVANLGTGVILSLVYGWQLTLLLVVIIPLIVLG 869
Query: 682 GAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTG 861
G K ++ + +++ ++G IA E + RT+ SL ++ + +L+V +
Sbjct: 870 GIIEMKLLSGQALKDKKQLEISGKIATEAIENFRTIVSLTREQKFETMYAQSLQVPYRNA 929
Query: 862 IVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIIND-PTFDRGLIFTVFFAVLSGSTSLG 1038
+ K GI F+ MY SYA F +G+ L+ TF+ + VF AV+ G+ + G
Sbjct: 930 MKKAHVFGITFSFTQAMMYFSYAACFRFGAYLVAQQLMTFEN--VMLVFSAVVFGAMAAG 987
Query: 1039 GALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKD 1218
+ A+ +AS ++R+I P+ID YS EG+ ++G++ F V F YP+R +
Sbjct: 988 NTSSFAPDYAKAKVSASHIIRIIEKTPEIDSYSTEGLKPTLLEGNVKFNGVQFNYPTRPN 1047
Query: 1219 IHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSL 1398
I VL+G+SLE+K G +ALVGSSGCGKST+V LL+RFYDP G V +DG +++++NV L
Sbjct: 1048 IPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSVFLDGKEIKQLNVQWL 1107
Query: 1399 REQIGIVSQEPVLFDGTIYENIKMGNEH--ATHDQVVEACKMANANDFIKRLPDGYGTRV 1572
R +GIVSQEP+LFD +I ENI G+ +H+++V A K AN + FI LPD Y TRV
Sbjct: 1108 RAHLGIVSQEPILFDCSIAENIAYGDNSRAVSHEEIVRAAKEANIHQFIDSLPDKYNTRV 1167
Query: 1573 GEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTII 1752
G+KG QLSGGQKQRIAIARALV+ P ILLLDEATSALDTE+E+ VQ ALD+A+ GRT I+
Sbjct: 1168 GDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIV 1227
Query: 1753 VAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM 1875
+AHRLSTI+N D I V + G + E G+H++L++++GI++ M
Sbjct: 1228 IAHRLSTIQNADLIVVIENGKVKEHGTHQQLLAQKGIYFSM 1268
Score = 352 bits (902), Expect = 5e-95
Identities = 217/529 (41%), Positives = 305/529 (57%), Gaps = 3/529 (0%)
Frame = +1
Query: 2200 DQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYD 2379
++M Y++ G+ G+ S CL G + K+R + F ++ Q+I ++D
Sbjct: 108 EEMAIYAYYYTGIGA--GVLIVAYIQVSLWCLA-AGRQIH-KIRQKFFHAIMNQEIGWFD 163
Query: 2380 DLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXX 2556
H G+L TR D + + ++ + SI T IGF GW+
Sbjct: 164 V--HDVGELNTRLTDDVSKINDGIGDKIGMFFQSITTFLAGFIIGFISGWKLTLVILAVS 221
Query: 2557 XXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLR 2736
+ ++ ++ Q +AG VA + + IRTV + Q++ Y + L
Sbjct: 222 PLIGLSSALWAKVLTSFTNKELQAYAKAGAVAEEVLAAIRTVIAFGGQQKELERYNKNLE 281
Query: 2737 EPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCG 2916
E N +K A T + L++ YA AF+ G+ V +V VFF+I
Sbjct: 282 EAKNVGIKKAITASISIGIAYLLVYASYALAFWYGTSLVLSNEYSIGEVLTVFFSILLGT 341
Query: 2917 QMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKP--ITGNISIRNVFFNY 3090
IG+ I AR AA +F +I++ IDS S G KP I GN+ +NV FNY
Sbjct: 342 FSIGHLAPNIEAFANARGAAFEIFKIIDNEPSIDSFSTKGY-KPDSIMGNLEFKNVHFNY 400
Query: 3091 PTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNL 3270
P+R + ++L+G L +K+G+TVALVG+SGCGKST + L++R Y+ +G++ IDG +IR +
Sbjct: 401 PSRSEVQILKGLNLKVKSGQTVALVGNSGCGKSTTVQLMQRLYDPLEGVVSIDGQDIRTI 460
Query: 3271 NISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGY 3450
N+ LRE + +VSQEP LF TI ENI YG +VT EI +A K AN ++FI+ LP +
Sbjct: 461 NVRYLREIIGVVSQEPVLFATTIAENIRYG-REDVTMDEIEKAVKEANAYDFIMKLPHQF 519
Query: 3451 DTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGR 3630
DT VGE+G QLSGGQKQRIAIARALVR+P +LLLDEATSALDTESE +VQ ALD A++GR
Sbjct: 520 DTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKAREGR 579
Query: 3631 TCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
T +VIAHRLST++N+DVIA G IVE+G HDEL+R+ IY K TQ
Sbjct: 580 TTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHDELMREKGIYFKLVMTQ 628
>gi|25453370|ref|NP_036755.2| P-glycoprotein/multidrug resistance 1;
ATP-binding cassette, sub-family B (MDR/TAP), member 1
(P-glycoprotein/multidrug resistance 1); ATP-binding
cassette sub-family B (MDR/TAP) member 1
(P-glycoprotein/multidrug resistance 1) [Rattus
norvegicus]
gi|19743730|gb|AAL92458.1| ATP-binding cassette protein B1b [Rattus
norvegicus]
Length = 1275
Score = 1051 bits (2717), Expect = 0.0
Identities = 559/1234 (45%), Positives = 791/1234 (63%), Gaps = 17/1234 (1%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNP 285
+G+F Y +D L + GT+AA+IHG PLL +V G MT F +A+ +
Sbjct: 35 FGMFRYADWLDKLCMALGTLAAIIHGTLLPLLMLVFGYMTDSFTQAETRILPSVTNQSEI 94
Query: 286 EGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAIL 465
+S ++ Y YY +G + +Y+Q++ + A R +HK+RQ + AI+
Sbjct: 95 NSTQTVSDSSLEEDMAMYAYYYTGIGAGVLIVAYIQVSLWCLAAGRQIHKIRQKFFHAIM 154
Query: 466 RQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTL 645
Q+I WFD G L RLTDD+ ++ +G+GDK + Q F AG+ +GF W +TL
Sbjct: 155 NQEIGWFDVNDAGELNTRLTDDVSKINDGIGDKLGMFFQSITTFSAGFIIGFISGWKLTL 214
Query: 646 VMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDR 825
V++ +PLI LS A +K + + T E + YA AGA+AEE ++IRTV + G K+EL+R
Sbjct: 215 VILAVSPLIGLSSAMWAKVLTSFTNKELQAYAKAGAVAEEVLAAIRTVIAFGGQKKELER 274
Query: 826 FYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVF 1005
+ LE ++ GI K I +G + L +Y+SYALAFWYG++L++++ + G + TVF
Sbjct: 275 YNKNLEEAKRVGIKKAITANISIGIAYLLVYASYALAFWYGTSLVLSNE-YSIGQVLTVF 333
Query: 1006 FAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFK 1185
F++L G+ S+G P++ +F ARGAA + ++I++ P ID +S +G D++ G++ FK
Sbjct: 334 FSILLGTFSIGHLAPNIEAFANARGAAYEIFKIIDNEPSIDSFSTKGHKPDSIMGNLEFK 393
Query: 1186 DVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDG 1365
+V+F YPSR ++ +LKG++L++K+G +ALVG+SGCGKST V LLQR YDP +G V IDG
Sbjct: 394 NVYFNYPSRSEVKILKGLNLKVKSGQTVALVGNSGCGKSTTVQLLQRLYDPIEGEVSIDG 453
Query: 1366 VDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKR 1545
D+R +NV LRE IG+VSQEPVLF TI ENI+ G E+ T D++ +A K ANA DFI +
Sbjct: 454 QDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMK 513
Query: 1546 LPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQ 1725
LP + T VGE+G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E VQ ALD+
Sbjct: 514 LPHKFNTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDK 573
Query: 1726 AQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXX 1905
A+ GRTTI++AHRLST+RN D I F G IVE G+HEELM ++GI++ +
Sbjct: 574 AREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHEELMKEKGIYFKLV-MTQTRGNE 632
Query: 1906 XEAGKDIEDTISESAHSHLXXXXXXX--XXXXXXXXIHQ---------LAEEVEECKAPP 2052
E G + ++ S++ S L IH+ E+V+E P
Sbjct: 633 IEPGNNAYESQSDTGASELTSEKSKSPLIRRSIRRSIHRRQDQERRLSSKEDVDE-DVPM 691
Query: 2053 TSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQ--MQANVYF 2226
S ++I K N + + + PVFA+V+++I V+S D Q N
Sbjct: 692 VSFWQILKLNISEWPYLVVGVLCAVINGCIQPVFAIVFSKIVGVFSRDDDHETKQRNCNL 751
Query: 2227 WCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKL 2406
+ +F++MG+ FV +F G+ GE LT +LR+ FK++LRQDI+++DD ++ TG L
Sbjct: 752 FSLLFLVMGMISFVTYFFQGFAFGKAGEILTKRLRYMVFKSMLRQDISWFDDHKNTTGSL 811
Query: 2407 CTRFATDAPNVRYVF-TRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYF 2583
TR A+DA NV+ +RL VV ++ + + + YGWQ +GG
Sbjct: 812 TTRLASDASNVKGAMGSRLAVVTQNVANLGTGIILSLVYGWQLTLLLVVIIPLIVLGGII 871
Query: 2584 EMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKH 2763
EM++ G+ ++D + LE +GK+A++A+E+ RTV SL R+++F Y + L+ P+ LK
Sbjct: 872 EMKLLSGQALKDKKELEISGKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNALKK 931
Query: 2764 AHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSF 2943
AH +G FAF+Q++I+F YAA F G+ V ++ M +V VF A+ F GNT+SF
Sbjct: 932 AHVFGITFAFTQAMIYFSYAACFRFGAYLVARELMTFENVMLVFSAVVFGAMAAGNTSSF 991
Query: 2944 IPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKP--ITGNISIRNVFFNYPTRKDTKVL 3117
PD KA+++AS + +IE IDS S G+ KP + GN+ V FNYPTR + VL
Sbjct: 992 APDYAKAKVSASHIIRIIEKIPEIDSYSTEGL-KPNWLEGNVKFNGVMFNYPTRPNIPVL 1050
Query: 3118 QGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQV 3297
QG + ++K G+T+ALVG SGCGKST++ LLERFYN G + +DG I+ LN+ LR +
Sbjct: 1051 QGLSFEVKKGQTLALVGSSGCGKSTVVQLLERFYNPMAGTVFLDGKEIKQLNVQWLRAHL 1110
Query: 3298 CIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKG 3474
IVSQEP LFDC+I ENI YG N R V+++EIV AA+ ANIH FI LP+ Y+T VG+KG
Sbjct: 1111 GIVSQEPILFDCSITENIAYGDNSRVVSHEEIVRAAREANIHQFIDSLPEKYNTRVGDKG 1170
Query: 3475 TQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHR 3654
TQLSGGQKQRIAIARALVR P +LLLDEATSALDTESEK+VQEALD A++GRTC+VIAHR
Sbjct: 1171 TQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHR 1230
Query: 3655 LSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIY 3756
LSTIQN+D+I ++ G++ E GTH +L+ + IY
Sbjct: 1231 LSTIQNADLIVVIQNGQVKEHGTHQQLLAQKGIY 1264
Score = 421 bits (1083), Expect = e-116
Identities = 236/581 (40%), Positives = 350/581 (59%), Gaps = 5/581 (0%)
Frame = +1
Query: 148 LITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSE 327
L+ G + AVI+G P+ AIV + VF R + D N N
Sbjct: 708 LVVGVLCAVINGCIQPVFAIVFSKIVGVFSR--DDDHETKQRNCN--------------- 750
Query: 328 VVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD--KQQT 501
+ + +LV+G++ F T + Q F E L +LR K++LRQ I WFD K T
Sbjct: 751 --LFSLLFLVMGMISFVTYFFQGFAFGKAGEILTKRLRYMVFKSMLRQDISWFDDHKNTT 808
Query: 502 GNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLS 681
G+LT RL D V+ +G + A++ Q A G + Y W +TL+++ PLIVL
Sbjct: 809 GSLTTRLASDASNVKGAMGSRLAVVTQNVANLGTGIILSLVYGWQLTLLLVVIIPLIVLG 868
Query: 682 GAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTG 861
G K ++ + +++ ++G IA E + RTV SL ++ + +L++ +
Sbjct: 869 GIIEMKLLSGQALKDKKELEISGKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNA 928
Query: 862 IVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIIND-PTFDRGLIFTVFFAVLSGSTSLG 1038
+ K GI F+ +Y SYA F +G+ L+ + TF+ + VF AV+ G+ + G
Sbjct: 929 LKKAHVFGITFAFTQAMIYFSYAACFRFGAYLVARELMTFEN--VMLVFSAVVFGAMAAG 986
Query: 1039 GALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKD 1218
+ A+ +AS ++R+I P+ID YS EG+ + ++G++ F V F YP+R +
Sbjct: 987 NTSSFAPDYAKAKVSASHIIRIIEKIPEIDSYSTEGLKPNWLEGNVKFNGVMFNYPTRPN 1046
Query: 1219 IHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSL 1398
I VL+G+S E+K G +ALVGSSGCGKST+V LL+RFY+P G V +DG +++++NV L
Sbjct: 1047 IPVLQGLSFEVKKGQTLALVGSSGCGKSTVVQLLERFYNPMAGTVFLDGKEIKQLNVQWL 1106
Query: 1399 REQIGIVSQEPVLFDGTIYENIKMGNEH--ATHDQVVEACKMANANDFIKRLPDGYGTRV 1572
R +GIVSQEP+LFD +I ENI G+ +H+++V A + AN + FI LP+ Y TRV
Sbjct: 1107 RAHLGIVSQEPILFDCSITENIAYGDNSRVVSHEEIVRAAREANIHQFIDSLPEKYNTRV 1166
Query: 1573 GEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTII 1752
G+KG QLSGGQKQRIAIARALV+ P ILLLDEATSALDTE+E+ VQ ALD+A+ GRT I+
Sbjct: 1167 GDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIV 1226
Query: 1753 VAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM 1875
+AHRLSTI+N D I V + G + E G+H++L++++GI++ M
Sbjct: 1227 IAHRLSTIQNADLIVVIQNGQVKEHGTHQQLLAQKGIYFSM 1267
Score = 345 bits (885), Expect = 5e-93
Identities = 208/488 (42%), Positives = 288/488 (58%), Gaps = 3/488 (0%)
Frame = +1
Query: 2323 KLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIVTICGA 2499
K+R + F ++ Q+I ++D + G+L TR D + + +L + SI T
Sbjct: 144 KIRQKFFHAIMNQEIGWFDV--NDAGELNTRLTDDVSKINDGIGDKLGMFFQSITTFSAG 201
Query: 2500 LGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRT 2679
IGF GW+ + ++ ++ Q +AG VA + + IRT
Sbjct: 202 FIIGFISGWKLTLVILAVSPLIGLSSAMWAKVLTSFTNKELQAYAKAGAVAEEVLAAIRT 261
Query: 2680 VHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQ 2859
V + Q++ Y + L E +K A T + L++ YA AF+ G+ V
Sbjct: 262 VIAFGGQKKELERYNKNLEEAKRVGIKKAITANISIGIAYLLVYASYALAFWYGTSLVLS 321
Query: 2860 QAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGI 3039
V VFF+I IG+ I AR AA +F +I++ IDS S G
Sbjct: 322 NEYSIGQVLTVFFSILLGTFSIGHLAPNIEAFANARGAAYEIFKIIDNEPSIDSFSTKGH 381
Query: 3040 VKP--ITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLER 3213
KP I GN+ +NV+FNYP+R + K+L+G L +K+G+TVALVG+SGCGKST + LL+R
Sbjct: 382 -KPDSIMGNLEFKNVYFNYPSRSEVKILKGLNLKVKSGQTVALVGNSGCGKSTTVQLLQR 440
Query: 3214 FYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIV 3393
Y+ +G + IDG +IR +N+ LRE + +VSQEP LF TI ENI YG NVT EI
Sbjct: 441 LYDPIEGEVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYG-RENVTMDEIE 499
Query: 3394 EAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSAL 3573
+A K AN ++FI+ LP ++T VGE+G QLSGGQKQRIAIARALVR+P +LLLDEATSAL
Sbjct: 500 KAVKEANAYDFIMKLPHKFNTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSAL 559
Query: 3574 DTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEI 3753
DTESE +VQ ALD A++GRT +VIAHRLST++N+DVIA G IVE+G H+EL+++ I
Sbjct: 560 DTESEAVVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHEELMKEKGI 619
Query: 3754 YQKFCETQ 3777
Y K TQ
Sbjct: 620 YFKLVMTQ 627
>gi|2506118|sp|P08183|MDR1_HUMAN Multidrug resistance protein 1
(P-glycoprotein 1) (CD243 antigen)
gi|1070659|pir||DVHU1 multidrug resistance protein 1 - human
gi|386862|gb|AAA59576.1| P glycoprotein
Length = 1280
Score = 1046 bits (2705), Expect = 0.0
Identities = 558/1243 (44%), Positives = 801/1243 (63%), Gaps = 19/1243 (1%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQN-SDFVVGVDN-- 276
+ +F Y+ +D L ++ GT+AA+IHGAG PL+ +V G MT +F A N D + + N
Sbjct: 37 FSMFRYSNWLDKLYMVVGTLAAIIHGAGLPLMMLVFGEMTDIFANAGNLEDLMSNITNRS 96
Query: 277 -VNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYL 453
+N G ++L+E ++ +Y YY +G + +Y+Q++ + A R +HK+R+ +
Sbjct: 97 DINDTGFF-MNLEE---DMTRYAYYYSGIGAGVLVAAYIQVSFWCLAAGRQIHKIRKQFF 152
Query: 454 KAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSW 633
AI+RQ+I WFD G L RLTDD+ ++ EG+GDK + Q A F G+ VGF W
Sbjct: 153 HAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQSMATFFTGFIVGFTRGW 212
Query: 634 SMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKR 813
+TLV++ +P++ LS A +K +++ T E YA AGA+AEE ++IRTV + G K+
Sbjct: 213 KLTLVILAISPVLGLSAAVWAKILSSFTDKELLAYAKAGAVAEEVLAAIRTVIAFGGQKK 272
Query: 814 ELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLI 993
EL+R+ LE ++ GI K I +G + L +Y+SYALAFWYG+TL+++ + G +
Sbjct: 273 ELERYNKNLEEAKRIGIKKAITANISIGAAFLLIYASYALAFWYGTTLVLSGE-YSIGQV 331
Query: 994 FTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGD 1173
TVFF+VL G+ S+G A P + +F ARGAA + ++I++ P ID YS G DN+KG+
Sbjct: 332 LTVFFSVLIGAFSVGQASPSIEAFANARGAAYEIFKIIDNKPSIDSYSKSGHKPDNIKGN 391
Query: 1174 ISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRV 1353
+ F++VHF YPSRK++ +LKG++L++++G +ALVG+SGCGKST V L+QR YDPT+G V
Sbjct: 392 LEFRNVHFSYPSRKEVKILKGLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTEGMV 451
Query: 1354 LIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAND 1533
+DG D+R +NV LRE IG+VSQEPVLF TI ENI+ G E+ T D++ +A K ANA D
Sbjct: 452 SVDGQDIRTINVRFLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYD 511
Query: 1534 FIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQG 1713
FI +LP + T VGE+G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E VQ
Sbjct: 512 FIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQV 571
Query: 1714 ALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM-TXXXX 1890
ALD+A+ GRTTI++AHRLST+RN D I F G IVE G+H+ELM ++GI++ + T
Sbjct: 572 ALDKARKGRTTIVIAHRLSTVRNADVIAGFDDGVIVEKGNHDELMKEKGIYFKLVTMQTA 631
Query: 1891 XXXXXXEAGKD--------IEDTISESAHSHLXXXXXXXXXXXXXXXIHQLA-EEVEECK 2043
E D +E + ++S S + +L+ +E +
Sbjct: 632 GNEVELENAADESKSEIDALEMSSNDSRSSLIRKRSTRRSVRGSQAQDRKLSTKEALDES 691
Query: 2044 APPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPAD--QMQAN 2217
PP S ++I K N + + + P FA+++++I V++ D + N
Sbjct: 692 IPPVSFWRIMKLNLTEWPYFVVGVFCAIINGGLQPAFAIIFSKIIGVFTRIDDPETKRQN 751
Query: 2218 VYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGT 2397
+ +F+ +GI F+ FF G+ GE LT +LR+ F+++LRQD++++DD ++ T
Sbjct: 752 SNLFSLLFLALGIISFITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTT 811
Query: 2398 GKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMG 2574
G L TR A DA V+ + +RL V+ +I + + I F YGWQ +
Sbjct: 812 GALTTRLANDAAQVKGAIGSRLAVITQNIANLGTGIIISFIYGWQLTLLLLAIVPIIAIA 871
Query: 2575 GYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTN 2754
G EM+M G+ ++D + LE AGK+A++A+E+ RTV SL ++++F Y + L+ P+ +
Sbjct: 872 GVVEMKMLSGQALKDKKELEGAGKIATEAIENFRTVVSLTQEQKFEHMYAQSLQVPYRNS 931
Query: 2755 LKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNT 2934
L+ AH +G F+F+Q++++F YA F G+ V + M DV VF A+ F +G
Sbjct: 932 LRKAHIFGITFSFTQAMMYFSYAGCFRFGAYLVAHKLMSFEDVLLVFSAVVFGAMAVGQV 991
Query: 2935 TSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIV-KPITGNISIRNVFFNYPTRKDTK 3111
+SF PD KA+++A+ + +IE IDS S G++ + GN++ V FNYPTR D
Sbjct: 992 SSFAPDYAKAKISAAHIIMIIEKTPLIDSYSTEGLMPNTLEGNVTFGEVVFNYPTRPDIP 1051
Query: 3112 VLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLRE 3291
VLQG +L++K G+T+ALVG SGCGKST++ LLERFY+ G +++DG I+ LN+ LR
Sbjct: 1052 VLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDGKEIKRLNVQWLRA 1111
Query: 3292 QVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGE 3468
+ IVSQEP LFDC+I ENI YG N R V+ +EIV AAK ANIH FI LP+ Y T VG+
Sbjct: 1112 HLGIVSQEPILFDCSIAENIAYGDNSRVVSQEEIVRAAKEANIHAFIESLPNKYSTKVGD 1171
Query: 3469 KGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIA 3648
KGTQLSGGQKQRIAIARALVR P +LLLDEATSALDTESEK+VQEALD A++GRTC+VIA
Sbjct: 1172 KGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIA 1231
Query: 3649 HRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
HRLSTIQN+D+I + G++ E GTH +L+ + IY Q
Sbjct: 1232 HRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMVSVQ 1274
>gi|42741659|ref|NP_000918.2| ATP-binding cassette sub-family B member
1; multidrug resistance 1; P glycoprotein 1; doxorubicin
resistance; colchicin sensitivity [Homo sapiens]
Length = 1280
Score = 1045 bits (2702), Expect = 0.0
Identities = 557/1243 (44%), Positives = 801/1243 (63%), Gaps = 19/1243 (1%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQN-SDFVVGVDN-- 276
+ +F Y+ +D L ++ GT+AA+IHGAG PL+ +V G MT +F A N D + + N
Sbjct: 37 FSMFRYSNWLDKLYMVVGTLAAIIHGAGLPLMMLVFGEMTDIFANAGNLEDLMSNITNRS 96
Query: 277 -VNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYL 453
+N G ++L+E ++ +Y YY +G + +Y+Q++ + A R +HK+R+ +
Sbjct: 97 DINDTGFF-MNLEE---DMTRYAYYYSGIGAGVLVAAYIQVSFWCLAAGRQIHKIRKQFF 152
Query: 454 KAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSW 633
AI+RQ+I WFD G L RLTDD+ ++ EG+GDK + Q A F G+ VGF W
Sbjct: 153 HAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQSMATFFTGFIVGFTRGW 212
Query: 634 SMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKR 813
+TLV++ +P++ LS A +K +++ T E YA AGA+AEE ++IRTV + G K+
Sbjct: 213 KLTLVILAISPVLGLSAAVWAKILSSFTDKELLAYAKAGAVAEEVLAAIRTVIAFGGQKK 272
Query: 814 ELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLI 993
EL+R+ LE ++ GI K I +G + L +Y+SYALAFWYG+TL+++ + G +
Sbjct: 273 ELERYNKNLEEAKRIGIKKAITANISIGAAFLLIYASYALAFWYGTTLVLSGE-YSIGQV 331
Query: 994 FTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGD 1173
TVFF+VL G+ S+G A P + +F ARGAA + ++I++ P ID YS G DN+KG+
Sbjct: 332 LTVFFSVLIGAFSVGQASPSIEAFANARGAAYEIFKIIDNKPSIDSYSKSGHKPDNIKGN 391
Query: 1174 ISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRV 1353
+ F++VHF YPSRK++ +LKG++L++++G +ALVG+SGCGKST V L+QR YDPT+G V
Sbjct: 392 LEFRNVHFSYPSRKEVKILKGLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTEGMV 451
Query: 1354 LIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAND 1533
+DG D+R +NV LRE IG+VSQEPVLF TI ENI+ G E+ T D++ +A K ANA D
Sbjct: 452 SVDGQDIRTINVRFLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYD 511
Query: 1534 FIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQG 1713
FI +LP + T VGE+G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E VQ
Sbjct: 512 FIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQV 571
Query: 1714 ALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM-TXXXX 1890
ALD+A+ GRTTI++AHRLST+RN D I F G IVE G+H+ELM ++GI++ + T
Sbjct: 572 ALDKARKGRTTIVIAHRLSTVRNADVIAGFDDGVIVEKGNHDELMKEKGIYFKLVTMQTA 631
Query: 1891 XXXXXXEAGKD--------IEDTISESAHSHLXXXXXXXXXXXXXXXIHQLA-EEVEECK 2043
E D +E + ++S S + +L+ +E +
Sbjct: 632 GNEVELENAADESKSEIDALEMSSNDSRSSLIRKRSTRRSVRGSQAQDRKLSTKEALDES 691
Query: 2044 APPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPAD--QMQAN 2217
PP S ++I K N + + + P FA+++++I V++ D + N
Sbjct: 692 IPPVSFWRIMKLNLTEWPYFVVGVFCAIINGGLQPAFAIIFSKIIGVFTRIDDPETKRQN 751
Query: 2218 VYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGT 2397
+ +F+ +GI F+ FF G+ GE LT +LR+ F+++LRQD++++DD ++ T
Sbjct: 752 SNLFSLLFLALGIISFITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTT 811
Query: 2398 GKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMG 2574
G L TR A DA V+ + +RL V+ +I + + I F YGWQ +
Sbjct: 812 GALTTRLANDAAQVKGAIGSRLAVITQNIANLGTGIIISFIYGWQLTLLLLAIVPIIAIA 871
Query: 2575 GYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTN 2754
G EM+M G+ ++D + LE +GK+A++A+E+ RTV SL ++++F Y + L+ P+ +
Sbjct: 872 GVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTQEQKFEHMYAQSLQVPYRNS 931
Query: 2755 LKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNT 2934
L+ AH +G F+F+Q++++F YA F G+ V + M DV VF A+ F +G
Sbjct: 932 LRKAHIFGITFSFTQAMMYFSYAGCFRFGAYLVAHKLMSFEDVLLVFSAVVFGAMAVGQV 991
Query: 2935 TSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIV-KPITGNISIRNVFFNYPTRKDTK 3111
+SF PD KA+++A+ + +IE IDS S G++ + GN++ V FNYPTR D
Sbjct: 992 SSFAPDYAKAKISAAHIIMIIEKTPLIDSYSTEGLMPNTLEGNVTFGEVVFNYPTRPDIP 1051
Query: 3112 VLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLRE 3291
VLQG +L++K G+T+ALVG SGCGKST++ LLERFY+ G +++DG I+ LN+ LR
Sbjct: 1052 VLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDGKEIKRLNVQWLRA 1111
Query: 3292 QVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGE 3468
+ IVSQEP LFDC+I ENI YG N R V+ +EIV AAK ANIH FI LP+ Y T VG+
Sbjct: 1112 HLGIVSQEPILFDCSIAENIAYGDNSRVVSQEEIVRAAKEANIHAFIESLPNKYSTKVGD 1171
Query: 3469 KGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIA 3648
KGTQLSGGQKQRIAIARALVR P +LLLDEATSALDTESEK+VQEALD A++GRTC+VIA
Sbjct: 1172 KGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIA 1231
Query: 3649 HRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
HRLSTIQN+D+I + G++ E GTH +L+ + IY Q
Sbjct: 1232 HRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMVSVQ 1274
>gi|31442763|gb|AAN07780.2| multidrug resistance p-glycoprotein
[Macaca fascicularis]
Length = 1283
Score = 1043 bits (2697), Expect = 0.0
Identities = 554/1243 (44%), Positives = 795/1243 (63%), Gaps = 19/1243 (1%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGV--DNV 279
+ +F Y+ +D L ++ GT+AA+IHGAG PL+ +V G MT F A N + + +N
Sbjct: 37 FSMFRYSNWLDKLYMVVGTLAAIIHGAGLPLMMLVFGDMTDTFANAGNLGDLGALLFNNT 96
Query: 280 NPEGLVP-ISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLK 456
N + + + ++ +Y YY +G + +Y+Q++ + A R +HK+R+ +
Sbjct: 97 NSSNITDTVPVMNLEEDMTRYAYYYSGIGAGVLVAAYIQVSFWCLAAGRQIHKIRKQFFH 156
Query: 457 AILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWS 636
AI+RQ+I WFD G L RLTDD+ ++ EG+GDK + Q A F G+ VGF W
Sbjct: 157 AIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQSMATFFTGFIVGFTRGWK 216
Query: 637 MTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRE 816
+TLV++ +P++ LS A +K +++ T E YA AGA+AEE ++IRTV + G K+E
Sbjct: 217 LTLVILAISPVLGLSAAVWAKILSSFTDKELLAYAKAGAVAEEVLAAIRTVIAFGGQKKE 276
Query: 817 LDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIF 996
L+R+ LE ++ GI K I +G + L +Y+SYALAFWYG+TL+++ + G +
Sbjct: 277 LERYNKNLEEAKRIGIKKAITANISIGAAFLLIYASYALAFWYGTTLVLSKE-YSIGQVL 335
Query: 997 TVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDI 1176
TVFF+VL G+ S+G A P + +F ARGAA + ++I++ P ID YS G DN+KG++
Sbjct: 336 TVFFSVLIGAFSVGQASPSIEAFANARGAAFEIFKIIDNKPSIDSYSKSGHKPDNIKGNL 395
Query: 1177 SFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVL 1356
F++VHF YPSRK++ +LKG++L++++G +ALVG+SGCGKST V L+QR YDPT+G V
Sbjct: 396 EFRNVHFSYPSRKEVKILKGLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTEGMVS 455
Query: 1357 IDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDF 1536
+DG D+R +NV LRE IG+VSQEPVLF TI ENI+ G E T D++ +A K ANA DF
Sbjct: 456 VDGQDIRTINVRFLREIIGVVSQEPVLFATTIAENIRYGREDVTMDEIEKAVKEANAYDF 515
Query: 1537 IKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGA 1716
I +LP + T VGE+G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E VQ A
Sbjct: 516 IMKLPQKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVA 575
Query: 1717 LDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXX- 1893
LD+A+ GRTTI++AHRLST+RN D I F G IVE G+H+ELM ++GI++ +
Sbjct: 576 LDKARKGRTTIVIAHRLSTVRNADVIAGFDDGVIVEKGNHDELMKEKGIYFKLVTMQTAG 635
Query: 1894 ----XXXXXEAGKDIEDTISESAH----SHLXXXXXXXXXXXXXXXIHQLA-EEVEECKA 2046
+ K DT+ S+H S + +L+ +E +
Sbjct: 636 NEIELENAADESKSEIDTLEMSSHDSGSSLIRKRSTRRSVRGSQGQDRKLSTKEALDESI 695
Query: 2047 PPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSL--PADQMQANV 2220
PP S ++I K N + + + P FA+++++I +++ A+ + N
Sbjct: 696 PPVSFWRIMKLNLTEWPYFVVGVFCAIINGGLQPAFAVIFSKIIGIFTRNDDAETKRQNS 755
Query: 2221 YFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTG 2400
+ +F+++GI F+ FF G+ GE LT +LR+ F+++LRQD++++DD ++ TG
Sbjct: 756 NLFSLLFLVLGIVSFITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTTG 815
Query: 2401 KLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGG 2577
L TR A DA V+ + +RL ++ +I + + I YGWQ + G
Sbjct: 816 ALTTRLANDAAQVKGAIGSRLAIITQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAIAG 875
Query: 2578 YFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNL 2757
EM+M G+ ++D + LE AGK+A++A+E+ RTV SL ++++F Y + L+ P+ +L
Sbjct: 876 VVEMKMLSGQALKDKKELEGAGKIATEAIENFRTVVSLTQEQKFEHMYDQSLQVPYRNSL 935
Query: 2758 KHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTT 2937
+ AH +G F+F+Q++++F YA F G+ V M DV VF A+ F +G +
Sbjct: 936 RKAHIFGITFSFTQAMMYFSYAGCFRFGAYLVAHSLMSFEDVLLVFSAVVFGAMAVGQVS 995
Query: 2938 SFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPIT--GNISIRNVFFNYPTRKDTK 3111
SF PD KA+++A+ + +IE IDS S G+ KP T GN++ V FNYPTR D
Sbjct: 996 SFAPDYAKAKVSAAHIIMIIEKTPLIDSYSTEGL-KPNTLEGNVTFNEVVFNYPTRLDIP 1054
Query: 3112 VLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLRE 3291
VLQG +L++K G+T+ALVG SGCGKST++ LLERFY+ G +++DG I+ LN+ LR
Sbjct: 1055 VLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDGKEIKQLNVQWLRA 1114
Query: 3292 QVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGE 3468
+ IVSQEP LFDC+I ENI YG N R V+ +EIV AAK ANIH FI LP+ Y T VG+
Sbjct: 1115 HLGIVSQEPILFDCSISENIAYGDNSRVVSQEEIVRAAKEANIHAFIESLPNKYSTRVGD 1174
Query: 3469 KGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIA 3648
KGTQLSGGQKQRIAIARALVR P +LLLDEATSALDTESEK+VQEALD A++GRTC+VIA
Sbjct: 1175 KGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIA 1234
Query: 3649 HRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
HRLSTIQN+D+I + G++ E GTH +L+ + IY Q
Sbjct: 1235 HRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMVSVQ 1277
>gi|307180|gb|AAA59575.1| P-glycoprotein [Homo sapiens]
Length = 1280
Score = 1043 bits (2696), Expect = 0.0
Identities = 557/1243 (44%), Positives = 800/1243 (63%), Gaps = 19/1243 (1%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQN-SDFVVGVDN-- 276
+ +F Y+ +D L ++ GT+AA+IHGAG PL+ +V G MT +F A N D + + N
Sbjct: 37 FSMFRYSNWLDKLYMVVGTLAAIIHGAGLPLMMLVFGEMTDIFANAGNLEDLMSNITNRS 96
Query: 277 -VNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYL 453
+N G ++L+E ++ +Y YY +G + +Y+Q++ + A R +HK+R+ +
Sbjct: 97 DINDTGFF-MNLEE---DMTRYAYYYSGIGAGVLVAAYIQVSFWCLAAGRQIHKIRKQFF 152
Query: 454 KAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSW 633
AI+RQ+I WFD G L RLTDD+ ++ E +GDK + Q A F G+ VGF W
Sbjct: 153 HAIMRQEIGWFDVHDVGELNTRLTDDVSKINEVIGDKIGMFFQSMATFFTGFIVGFTRGW 212
Query: 634 SMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKR 813
+TLV++ +P++ LS A +K +++ T E YA AGA+AEE ++IRTV + G K+
Sbjct: 213 KLTLVILAISPVLGLSAAVWAKILSSFTDKELLAYAKAGAVAEEVLAAIRTVIAFGGQKK 272
Query: 814 ELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLI 993
EL+R+ LE ++ GI K I +G + L +Y+SYALAFWYG+TL+++ + G +
Sbjct: 273 ELERYNKNLEEAKRIGIKKAITANISIGAAFLLIYASYALAFWYGTTLVLSGE-YSIGQV 331
Query: 994 FTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGD 1173
TVFF+VL G+ S+G A P + +F ARGAA + ++I++ P ID YS G DN+KG+
Sbjct: 332 LTVFFSVLIGAFSVGQASPSIEAFANARGAAYEIFKIIDNKPSIDSYSKSGHKPDNIKGN 391
Query: 1174 ISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRV 1353
+ F++VHF YPSRK++ +LKG++L++++G +ALVG+SGCGKST V L+QR YDPT+G V
Sbjct: 392 LEFRNVHFSYPSRKEVKILKGLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTEGMV 451
Query: 1354 LIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAND 1533
+DG D+R +NV LRE IG+VSQEPVLF TI ENI+ G E+ T D++ +A K ANA D
Sbjct: 452 SVDGQDIRTINVRFLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYD 511
Query: 1534 FIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQG 1713
FI +LP + T VGE+G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E VQ
Sbjct: 512 FIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQV 571
Query: 1714 ALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM-TXXXX 1890
ALD+A+ GRTTI++AHRLST+RN D I F G IVE G+H+ELM ++GI++ + T
Sbjct: 572 ALDKARKGRTTIVIAHRLSTVRNADVIAGFDDGVIVEKGNHDELMKEKGIYFKLVTMQTA 631
Query: 1891 XXXXXXEAGKD--------IEDTISESAHSHLXXXXXXXXXXXXXXXIHQLA-EEVEECK 2043
E D +E + ++S S + +L+ +E +
Sbjct: 632 GNEVELENAADESKSEIDALEMSSNDSRSSLIRKRSTRRSVRGSQAQDRKLSTKEALDES 691
Query: 2044 APPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPAD--QMQAN 2217
PP S ++I K N + + + P FA+++++I V++ D + N
Sbjct: 692 IPPVSFWRIMKLNLTEWPYFVVGVFCAIINGGLQPAFAIIFSKIIGVFTRIDDPETKRQN 751
Query: 2218 VYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGT 2397
+ +F+ +GI F+ FF G+ GE LT +LR+ F+++LRQD++++DD ++ T
Sbjct: 752 SNLFSLLFLALGIISFITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTT 811
Query: 2398 GKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMG 2574
G L TR A DA V+ + +RL V+ +I + + I F YGWQ +
Sbjct: 812 GALTTRLANDAAQVKGAIGSRLAVITQNIANLGTGIIISFIYGWQLTLLLLAIVPIIAIA 871
Query: 2575 GYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTN 2754
G EM+M G+ ++D + LE AGK+A++A+E+ RTV SL ++++F Y + L+ P+ +
Sbjct: 872 GVVEMKMLSGQALKDKKELEGAGKIATEAIENFRTVVSLTQEQKFEHMYAQSLQVPYRNS 931
Query: 2755 LKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNT 2934
L+ AH +G F+F+Q++++F YA F G+ V + M DV VF A+ F +G
Sbjct: 932 LRKAHIFGITFSFTQAMMYFSYAGCFRFGAYLVAHKLMSFEDVLLVFSAVVFGAMAVGQV 991
Query: 2935 TSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIV-KPITGNISIRNVFFNYPTRKDTK 3111
+SF PD KA+++A+ + +IE IDS S G++ + GN++ V FNYPTR D
Sbjct: 992 SSFAPDYAKAKISAAHIIMIIEKTPLIDSYSTEGLMPNTLEGNVTFGEVVFNYPTRPDIP 1051
Query: 3112 VLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLRE 3291
VLQG +L++K G+T+ALVG SGCGKST++ LLERFY+ G +++DG I+ LN+ LR
Sbjct: 1052 VLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDGKEIKRLNVQWLRA 1111
Query: 3292 QVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGE 3468
+ IVSQEP LFDC+I ENI YG N R V+ +EIV AAK ANIH FI LP+ Y T VG+
Sbjct: 1112 HLGIVSQEPILFDCSIAENIAYGDNSRVVSQEEIVRAAKEANIHAFIESLPNKYSTKVGD 1171
Query: 3469 KGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIA 3648
KGTQLSGGQKQRIAIARALVR P +LLLDEATSALDTESEK+VQEALD A++GRTC+VIA
Sbjct: 1172 KGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIA 1231
Query: 3649 HRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
HRLSTIQN+D+I + G++ E GTH +L+ + IY Q
Sbjct: 1232 HRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMVSVQ 1274
>gi|46394984|gb|AAS91648.1| multidrug resistance protein;
P-glycoprotein [Macaca mulatta]
Length = 1283
Score = 1042 bits (2695), Expect = 0.0
Identities = 553/1243 (44%), Positives = 794/1243 (63%), Gaps = 19/1243 (1%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGV--DNV 279
+ +F Y+ +D L ++ GT+AA+IHGAG PL+ +V G MT F A N + + +N
Sbjct: 37 FSMFRYSNWLDKLYMVVGTLAAIIHGAGLPLMMLVFGDMTDTFANAGNLGDLGALLFNNT 96
Query: 280 NPEGLVP-ISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLK 456
N + + + ++ +Y YY +G + +Y+Q++ + A R +HK+R+ +
Sbjct: 97 NSSNITDTVPVMNLEEDMTRYAYYYSGIGAGVLVAAYIQVSFWCLAAGRQIHKIRKQFFH 156
Query: 457 AILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWS 636
AI+RQ+I WFD G L RLTD++ ++ EG+GDK + Q A F G+ VGF W
Sbjct: 157 AIMRQEIGWFDVHDVGELNTRLTDEVSKINEGIGDKIGMFFQSMATFFTGFIVGFTRGWK 216
Query: 637 MTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRE 816
+TLV++ +P++ LS A +K +++ T E YA AG +AEE ++IRTV + G K+E
Sbjct: 217 LTLVILAISPILGLSAAAWAKILSSFTDKELLAYAKAGVVAEEVLAAIRTVIAFGGQKKE 276
Query: 817 LDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIF 996
L+R+ LE ++ GI K I +G + L +Y+SYALAFWYG+TL+++ + G +
Sbjct: 277 LERYNKNLEEAKRIGIKKAITANISIGAAFLLIYASYALAFWYGTTLVLSKE-YSIGQVL 335
Query: 997 TVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDI 1176
TVFF+VL G+ S+G A P + +F ARGAA + ++I++ P ID YS G DN+KG++
Sbjct: 336 TVFFSVLIGAFSVGQASPSIEAFANARGAAFEIFKIIDNKPSIDSYSKSGHKPDNIKGNL 395
Query: 1177 SFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVL 1356
F++VHF YPSRK++ +LKG++L++++G +ALVG+SGCGKST V L+QR YDPT+G V
Sbjct: 396 EFRNVHFSYPSRKEVKILKGLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTEGMVS 455
Query: 1357 IDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDF 1536
+DG D+R +NV LRE IG+VSQEPVLF TI ENI+ G E T D++ +A K ANA DF
Sbjct: 456 VDGQDIRTINVRFLREIIGVVSQEPVLFATTIAENIRYGREDVTMDEIEKAVKEANAYDF 515
Query: 1537 IKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGA 1716
I +LP + T VGE+G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E VQ A
Sbjct: 516 IMKLPQKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVA 575
Query: 1717 LDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXX- 1893
LD+A+ GRTTI++AHRLST+RN D I F G IVE G+H+ELM ++GI++ +
Sbjct: 576 LDKARKGRTTIVIAHRLSTVRNADVIAGFDDGVIVEKGNHDELMKEKGIYFKLVTMQTAG 635
Query: 1894 ----XXXXXEAGKDIEDTISESAH----SHLXXXXXXXXXXXXXXXIHQLA-EEVEECKA 2046
+ K DT+ S+H S + +L+ +E +
Sbjct: 636 NEIELENAADESKSEIDTLEMSSHDSGSSLIRKRSTRRSVRGSQGQDRKLSTKEALDESI 695
Query: 2047 PPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSL--PADQMQANV 2220
PP S ++I K N + + + P FA+++++I +++ A+ Q N
Sbjct: 696 PPVSFWRIMKLNLTEWPYFVVGVFCAIINGGLQPAFAVIFSKIIGIFTRNDDAETKQQNS 755
Query: 2221 YFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTG 2400
+ +F+++GI F+ FF G+ GE LT +LR+ F+++LRQD++++DD ++ TG
Sbjct: 756 NLFSLLFLVLGIVSFITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTTG 815
Query: 2401 KLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGG 2577
L TR A DA V+ + +RL ++ +I + + I YGWQ + G
Sbjct: 816 ALTTRLANDAAQVKGAIGSRLAIITQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAIAG 875
Query: 2578 YFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNL 2757
EM+M G+ ++D + LE AGK+A++A+E+ RTV SL ++++F Y + L+ P+ +L
Sbjct: 876 VVEMKMLSGQALKDKKELEGAGKIATEAIENFRTVVSLTQEQKFEHMYDQSLQVPYRNSL 935
Query: 2758 KHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTT 2937
+ AH +G F+F+Q++++F YA F G+ V M DV VF A+ F +G +
Sbjct: 936 RKAHIFGITFSFTQAMMYFSYAGCFRFGAYLVAHSLMSFEDVLLVFSAVVFGAMAVGQVS 995
Query: 2938 SFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPIT--GNISIRNVFFNYPTRKDTK 3111
SF PD KA+++A+ + +IE IDS S G+ KP T GN++ V FNYPTR D
Sbjct: 996 SFAPDYAKAKVSAAHIIMIIEKTPLIDSYSTEGL-KPNTLEGNVTFNEVVFNYPTRLDIP 1054
Query: 3112 VLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLRE 3291
VLQG +L++K G+T+ALVG SGCGKST++ LLERFY+ G +++DG I+ LN+ LR
Sbjct: 1055 VLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDGKEIKQLNVQWLRA 1114
Query: 3292 QVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGE 3468
+ IVSQEP LFDC+I ENI YG N R V+ +EIV AAK ANIH FI LP+ Y T VG+
Sbjct: 1115 HLGIVSQEPILFDCSISENIAYGDNSRVVSQEEIVRAAKEANIHAFIESLPNKYSTRVGD 1174
Query: 3469 KGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIA 3648
KGTQLSGGQKQRIAIARALVR P +LLLDEATSALDTESEK+VQEALD A++GRTC+VIA
Sbjct: 1175 KGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIA 1234
Query: 3649 HRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
HRLSTIQN+D+I + G++ E GTH +L+ + IY Q
Sbjct: 1235 HRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMVSVQ 1277
>gi|22775296|gb|AAN07779.1| multidrug resistance p-glycoprotein
[Macaca mulatta]
Length = 1283
Score = 1040 bits (2689), Expect = 0.0
Identities = 552/1243 (44%), Positives = 794/1243 (63%), Gaps = 19/1243 (1%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGV--DNV 279
+ +F Y+ +D L ++ G +AA+IHGAG PL+ +V G MT F A N + + +N
Sbjct: 37 FSMFRYSNWLDKLYMVVGILAAIIHGAGLPLMMLVFGDMTDTFANAGNLGDLGALLFNNT 96
Query: 280 NPEGLVP-ISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLK 456
N + + + ++ +Y YY +G + +Y+Q++ + A R +HK+R+ +
Sbjct: 97 NSSNITDTVPVMNLEEDMTRYAYYYSGIGAGVLVAAYIQVSFWCLAAGRQIHKIRKQFFH 156
Query: 457 AILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWS 636
AI+RQ+I WFD G L RLTDD+ ++ EG+GDK + Q A F G+ VGF W
Sbjct: 157 AIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQSMATFFTGFIVGFTRGWK 216
Query: 637 MTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRE 816
+TLV++ +P++ +S A +K +++ T E YA AGA+AEE ++IRTV + G K+E
Sbjct: 217 LTLVILAISPVLGVSAAAWAKILSSFTDKELLAYAKAGAVAEEVLAAIRTVIAFGGQKKE 276
Query: 817 LDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIF 996
L+R+ LE ++ GI K I +G + L +Y+SYALAFWYG+TL+++ + G +
Sbjct: 277 LERYNKNLEEAKRIGIKKAITANISIGAAFLLIYASYALAFWYGTTLVLSKE-YSIGQVL 335
Query: 997 TVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDI 1176
TVFF+VL G+ S+G A P + +F ARGAA + ++I++ P ID YS G DN+KG++
Sbjct: 336 TVFFSVLIGAFSVGQASPSIEAFANARGAAFEIFKIIDNKPSIDSYSKSGHKPDNIKGNL 395
Query: 1177 SFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVL 1356
F++VHF YPSRK++ +LKG++L++++G +ALVG+SGCGKST V L+QR YDPT+G V
Sbjct: 396 EFRNVHFSYPSRKEVKILKGLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTEGMVS 455
Query: 1357 IDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDF 1536
+DG D+R +NV LRE IG+VSQEPVLF TI ENI+ G E T D++ +A K ANA DF
Sbjct: 456 VDGQDIRTINVRFLREIIGVVSQEPVLFATTIAENIRYGREDVTMDEIEKAVKEANAYDF 515
Query: 1537 IKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGA 1716
I +LP + T VGE+G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E VQ A
Sbjct: 516 IMKLPQKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVA 575
Query: 1717 LDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXX- 1893
LD+A+ GRTTI++AHRLST+RN D I F G IVE G+H+ELM ++GI++ +
Sbjct: 576 LDKARKGRTTIVIAHRLSTVRNADVIAGFDDGVIVEKGNHDELMKEKGIYFKLVTMQTAG 635
Query: 1894 ----XXXXXEAGKDIEDTISESAH----SHLXXXXXXXXXXXXXXXIHQLA-EEVEECKA 2046
+ K DT+ S+H S + +L+ +E +
Sbjct: 636 NEIELENAADESKSEIDTLEMSSHDSGSSLIRKRSTRRSVRGSQGQDRKLSTKEALDESI 695
Query: 2047 PPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSL--PADQMQANV 2220
PP S ++I K N + + + P FA+++++I +++ A+ + N
Sbjct: 696 PPVSFWRIMKLNLTEWPYFVVGVFCAIINGGLQPAFAVIFSKIIGIFTRNDDAETKRQNS 755
Query: 2221 YFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTG 2400
+ +F+++GI F+ FF G+ GE LT +LR+ F+++LRQD++++DD ++ TG
Sbjct: 756 NLFSLLFLVLGIVSFITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTTG 815
Query: 2401 KLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGG 2577
L TR A DA V+ + +RL ++ +I + + I YGWQ + G
Sbjct: 816 ALTTRLANDAAQVKGAIGSRLAIITQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAIAG 875
Query: 2578 YFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNL 2757
EM+M G+ ++D + LE AGK+A++A+E+ RTV SL ++++F Y + L+ P+ +L
Sbjct: 876 VVEMKMLSGQALKDKKELEGAGKIATEAIENFRTVVSLTQEQKFEHMYDQSLQVPYRNSL 935
Query: 2758 KHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTT 2937
+ AH +G F+F+Q++++F YA F G+ V M DV VF A+ F +G +
Sbjct: 936 RKAHIFGITFSFTQAMMYFSYAGCFRFGAYLVAHSLMSFEDVLLVFSAVVFGAMAVGQVS 995
Query: 2938 SFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPIT--GNISIRNVFFNYPTRKDTK 3111
SF PD KA+++A+ + +IE IDS S G+ KP T GN++ V FNYPTR D
Sbjct: 996 SFAPDYAKAKVSAAHIIMIIEKTPLIDSYSTEGL-KPNTLEGNVTFNEVVFNYPTRLDIP 1054
Query: 3112 VLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLRE 3291
VLQG +L++K G+T+ALVG SGCGKST++ LLERFY+ G +++DG I+ LN+ LR
Sbjct: 1055 VLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDGKEIKQLNVQWLRA 1114
Query: 3292 QVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGE 3468
+ IVSQEP LFDC+I ENI YG N R V+ +EIV AAK ANIH FI LP+ Y T VG+
Sbjct: 1115 HLGIVSQEPILFDCSISENIAYGDNSRVVSQEEIVRAAKEANIHAFIESLPNKYSTRVGD 1174
Query: 3469 KGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIA 3648
KGTQLSGGQKQRIAIARALVR P +LLLDEATSALDTESEK+VQEALD A++GRTC+VIA
Sbjct: 1175 KGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIA 1234
Query: 3649 HRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
HRLSTIQN+D+I + G++ E GTH +L+ + IY Q
Sbjct: 1235 HRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMVSVQ 1277
>gi|2353264|gb|AAB69423.1| P-glycoprotein [Homo sapiens]
Length = 1279
Score = 1039 bits (2687), Expect = 0.0
Identities = 557/1243 (44%), Positives = 800/1243 (63%), Gaps = 19/1243 (1%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQN-SDFVVGVDN-- 276
+ +F Y+ +D L ++ GT+AA+IHGAG PL+ +V G MT +F A N D + + N
Sbjct: 37 FSMFRYSNWLDKLYMVVGTLAAIIHGAGLPLMMLVFGEMTDIFANAGNLEDLMSNITNRS 96
Query: 277 -VNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYL 453
+N G ++L+E ++ +Y YY +G + +Y+Q++ + A R +HK+R+ +
Sbjct: 97 DINDTGFF-MNLEE---DMTRYAYYYSGIGAGVLVAAYIQVSFWCLAAGRQIHKIRKQFF 152
Query: 454 KAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSW 633
AI+RQ+I WFD G L RLTDD+ ++ EG+GDK + Q A F G+ VGF W
Sbjct: 153 HAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQSMATFFTGFIVGFTRGW 212
Query: 634 SMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKR 813
+TLV++ +P++ LS A +K +++ T E YA AGA+AEE ++IRTV + G K+
Sbjct: 213 KLTLVILAISPVLGLSAAVWAKILSSFTDKELLAYAKAGAVAEEVLAAIRTVIAFGGQKK 272
Query: 814 ELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLI 993
EL+R+ LE ++ GI K I +G + L +Y+SYALAFWYG+TL+++ + G +
Sbjct: 273 ELERYNKNLEEAKRIGIKKAITANISIGAAFLLIYASYALAFWYGTTLVLSGE-YSIGQV 331
Query: 994 FTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGD 1173
TVF +VL G+ S+G A P + +F ARGAA + ++I++ P ID YS G DN+KG+
Sbjct: 332 LTVF-SVLIGAFSVGQASPSIEAFANARGAAYEIFKIIDNKPSIDSYSKSGHKPDNIKGN 390
Query: 1174 ISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRV 1353
+ F++VHF YPSRK++ +LKG++L++++G +ALVG+SGCGKST V L+QR YDPT+G V
Sbjct: 391 LEFRNVHFSYPSRKEVKILKGLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTEGMV 450
Query: 1354 LIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAND 1533
+DG D+R +NV LRE IG+VSQEPVLF TI ENI+ G E+ T D++ +A K ANA D
Sbjct: 451 SVDGQDIRTINVRFLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYD 510
Query: 1534 FIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQG 1713
FI +LP + T VGE+G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E VQ
Sbjct: 511 FIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQV 570
Query: 1714 ALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM-TXXXX 1890
ALD+A+ GRTTI++AHRLST+RN D I F G IVE G+H+ELM ++GI++ + T
Sbjct: 571 ALDKARKGRTTIVIAHRLSTVRNADVIAGFDDGVIVEKGNHDELMKEKGIYFKLVTMQTA 630
Query: 1891 XXXXXXEAGKD--------IEDTISESAHSHLXXXXXXXXXXXXXXXIHQLA-EEVEECK 2043
E D +E + ++S S + +L+ +E +
Sbjct: 631 GNEVELENAADESKSEIDALEMSSNDSRSSLIRKRSTRRSVRGSQAQDRKLSTKEALDES 690
Query: 2044 APPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPAD--QMQAN 2217
PP S ++I K N + + + P FA+++++I V++ D + N
Sbjct: 691 IPPVSFWRIMKLNLTEWPYFVVGVFCAIINGGLQPAFAIIFSKIIGVFTRIDDPETKRQN 750
Query: 2218 VYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGT 2397
+ +F+ +GI F+ FF G+ GE LT +LR+ F+++LRQD++++DD ++ T
Sbjct: 751 SNLFSLLFLALGIISFITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTT 810
Query: 2398 GKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMG 2574
G L TR A DA V+ + +RL V+ +I + + I F YGWQ +
Sbjct: 811 GALTTRLANDAAQVKGAIGSRLAVITQNIANLGTGIIISFIYGWQLTLLLLAIVPIIAIA 870
Query: 2575 GYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTN 2754
G EM+M G+ ++D + LE AGK+A++A+E+ RTV SL ++++F Y + L+ P+ +
Sbjct: 871 GVVEMKMLSGQALKDKKELEGAGKIATEAIENFRTVVSLTQEQKFEHMYAQSLQVPYRNS 930
Query: 2755 LKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNT 2934
L+ AH +G F+F+Q++++F YA F G+ V + M DV VF A+ F +G
Sbjct: 931 LRKAHIFGITFSFTQAMMYFSYAGCFRFGAYLVAHKLMSFEDVLLVFSAVVFGAMAVGQV 990
Query: 2935 TSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIV-KPITGNISIRNVFFNYPTRKDTK 3111
+SF PD KA+++A+ + +IE IDS S G++ + GN++ V FNYPTR D
Sbjct: 991 SSFAPDYAKAKISAAHIIMIIEKTPLIDSYSTEGLMPNTLEGNVTFGEVVFNYPTRPDIP 1050
Query: 3112 VLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLRE 3291
VLQG +L++K G+T+ALVG SGCGKST++ LLERFY+ G +++DG I+ LN+ LR
Sbjct: 1051 VLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDGKEIKRLNVQWLRA 1110
Query: 3292 QVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGE 3468
+ IVSQEP LFDC+I ENI YG N R V+ +EIV AAK ANIH FI LP+ Y T VG+
Sbjct: 1111 HLGIVSQEPILFDCSIAENIAYGDNSRVVSQEEIVRAAKEANIHAFIESLPNKYSTKVGD 1170
Query: 3469 KGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIA 3648
KGTQLSGGQKQRIAIARALVR P +LLLDEATSALDTESEK+VQEALD A++GRTC+VIA
Sbjct: 1171 KGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIA 1230
Query: 3649 HRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
HRLSTIQN+D+I + G++ E GTH +L+ + IY Q
Sbjct: 1231 HRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMVSVQ 1273
>gi|126924|sp|P21448|MDR1_CRIGR Multidrug resistance protein 1
(P-glycoprotein 1)
gi|191165|gb|AAA68883.1| p-glycoprotein isoform I
Length = 1276
Score = 1039 bits (2687), Expect = 0.0
Identities = 556/1243 (44%), Positives = 787/1243 (62%), Gaps = 19/1243 (1%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQN--SDFVVGVDNV 279
+ +F Y +D L ++ GT+AA+IHG PL+ +V G MT F N ++ V
Sbjct: 36 FTMFRYAGWLDRLYMLVGTLAAIIHGVALPLMMLVFGDMTDSFASVGNIPTNATNNATQV 95
Query: 280 NPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKA 459
N + + E+ Y YY +G + +Y+Q++ + A R +HK+RQ + A
Sbjct: 96 NASDI----FGKLEEEMTTYAYYYTGIGAGVLIVAYIQVSFWCLAAGRQIHKIRQKFFHA 151
Query: 460 ILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSM 639
I+ Q+I WFD G L RLTDD+ ++ EG+GDK + Q A F G+ +GF W +
Sbjct: 152 IMNQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQAMATFFGGFIIGFTRGWKL 211
Query: 640 TLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKREL 819
TLV++ +P++ LS +K +++ T E + YA AGA+AEE ++IRTV + G K+EL
Sbjct: 212 TLVILAISPVLGLSAGIWAKILSSFTDKELQAYAKAGAVAEEVLAAIRTVIAFGGQKKEL 271
Query: 820 DRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFT 999
+R+ N LE ++ GI K I +G + L +Y+SYALAFWYG++L+I+ + G + T
Sbjct: 272 ERYNNNLEEAKRLGIKKAITANISMGAAFLLIYASYALAFWYGTSLVISKE-YSIGQVLT 330
Query: 1000 VFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDIS 1179
VFFAVL G+ S+G A P++ +F ARGAA + +I++ P ID +S G DN+KG++
Sbjct: 331 VFFAVLIGAFSIGQASPNIEAFANARGAAYEIFNIIDNKPSIDSFSKNGYKPDNIKGNLE 390
Query: 1180 FKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLI 1359
FK++HF YPSRKD+ +LKG++L++++G +ALVG+SGCGKST V LLQR YDPT+G V I
Sbjct: 391 FKNIHFSYPSRKDVQILKGLNLKVQSGQTVALVGNSGCGKSTTVQLLQRLYDPTEGVVSI 450
Query: 1360 DGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFI 1539
DG D+R +NV LRE IG+VSQEPVLF TI ENI+ G E+ T D++ +A K ANA DFI
Sbjct: 451 DGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFI 510
Query: 1540 KRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGAL 1719
+LP + T VGE+G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E VQ AL
Sbjct: 511 MKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAAL 570
Query: 1720 DQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXX 1899
D+A+ GRTTI++AHRLST+RN D I F G IVE G+HEELM ++GI++ +
Sbjct: 571 DKAREGRTTIVIAHRLSTVRNADIIAGFDGGVIVEQGNHEELMREKGIYFKLV-MTQTAG 629
Query: 1900 XXXEAGKDIEDTISE----------SAHSHLXXXXXXXXXXXXXXXIHQLA-EEVEECKA 2046
E G ++ ++ +E SA S + +L+ +E +
Sbjct: 630 NEIELGNEVGESKNEIDNLDMSSKDSASSLIRRRSTRRSIRGPHDQDRKLSTKEALDEDV 689
Query: 2047 PPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQ--MQANV 2220
PP S ++I K N + + ++ P F+++++++ V++ D + +
Sbjct: 690 PPISFWRILKLNSSEWPYFVVGIFCAIVNGALQPAFSIIFSKVVGVFTRNTDDETKRHDS 749
Query: 2221 YFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTG 2400
+ +F+++G+ F+ FF G+ GE LT +LR+ FK++LRQD++++D+ ++ TG
Sbjct: 750 NLFSLLFLILGVISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDNPKNTTG 809
Query: 2401 KLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGG 2577
L TR A DA V+ RL V+ +I + + I YGWQ + G
Sbjct: 810 ALTTRLANDAGQVKGATGARLAVITQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAIAG 869
Query: 2578 YFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNL 2757
EM+M G+ ++D + LE +GK+A++A+E+ RTV SL R+++F Y + L+ P+ L
Sbjct: 870 VVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTREQKFENMYAQSLQIPYRNAL 929
Query: 2758 KHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTT 2937
K AH +G F+F+Q++++F YAA F G+ V ++ M +V VF AI F +G +
Sbjct: 930 KKAHVFGITFSFTQAMMYFSYAACFRFGAYLVARELMTFENVLLVFSAIVFGAMAVGQVS 989
Query: 2938 SFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPIT--GNISIRNVFFNYPTRKDTK 3111
SF PD KA+++AS + +IE IDS S G+ KP T GN+ V FNYPTR D
Sbjct: 990 SFAPDYAKAKVSASHIIMIIEKVPSIDSYSTGGL-KPNTLEGNVKFNEVVFNYPTRPDIP 1048
Query: 3112 VLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLRE 3291
VLQG L++K G+T+ALVG SGCGKST++ LLERFY+ G + +DG + LN+ LR
Sbjct: 1049 VLQGLNLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGTVFLDGKEVNQLNVQWLRA 1108
Query: 3292 QVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGE 3468
+ IVSQEP LFDC+I ENI YG N R V+ EI AAK ANIH FI LPD Y+T VG+
Sbjct: 1109 HLGIVSQEPILFDCSIAENIAYGDNSRVVSQDEIERAAKEANIHQFIESLPDKYNTRVGD 1168
Query: 3469 KGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIA 3648
KGTQLSGGQKQRIAIARALVR P +LLLDEATSALDTESEK+VQEALD A++GRTC+VIA
Sbjct: 1169 KGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIA 1228
Query: 3649 HRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
HRLSTIQN+D+I ++ GK+ E GTH +L+ + IY Q
Sbjct: 1229 HRLSTIQNADLIVVIQNGKVKEHGTHQQLLAQKGIYFSMVSVQ 1271
>gi|46394982|gb|AAS91647.1| multidrug resistance protein 1;
P-glycoprotein [Canis familiaris]
Length = 1281
Score = 1038 bits (2685), Expect = 0.0
Identities = 555/1247 (44%), Positives = 795/1247 (63%), Gaps = 20/1247 (1%)
Frame = +1
Query: 97 LTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRA---QNSDFVVG 267
++ + +F Y+ +D L ++ GT+AA+IHGA PL+ +V G MT F A +N F V
Sbjct: 34 VSTFAMFRYSNWLDRLYMLVGTMAAIIHGAALPLMMLVFGNMTDSFANAGISRNKTFPV- 92
Query: 268 VDNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQN 447
+ N + ++ E+ Y YY +G + +Y+Q++ + A R + K+R+
Sbjct: 93 IINESITNNTQHFINHLEEEMTTYAYYYSGIGAGVLVAAYIQVSFWCLAAGRQILKIRKQ 152
Query: 448 YLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFY 627
+ AI+RQ+I WFD G L RLTDD+ ++ EG+GDK + Q A F G+ VGF
Sbjct: 153 FFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQSIATFFTGFIVGFTR 212
Query: 628 SWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGH 807
W +TLV++ +P++ LS A +K +++ T E YA AGA+AEE ++IRTV + G
Sbjct: 213 GWKLTLVILAISPVLGLSAAIWAKILSSFTDKELLAYAKAGAVAEEVLAAIRTVIAFGGQ 272
Query: 808 KRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRG 987
K+EL+R+ LE ++ GI K I +G + L +Y+SYALAFWYG++L+++ + G
Sbjct: 273 KKELERYNKNLEEAKRIGIKKAITANISIGAAFLLIYASYALAFWYGTSLVLSSE-YSIG 331
Query: 988 LIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMK 1167
+ TVFF+VL G+ S+G A P + +F ARGAA + ++I++ P ID YS G DN+K
Sbjct: 332 QVLTVFFSVLIGAFSIGQASPSIEAFANARGAAYEIFKIIDNKPSIDSYSKSGHKPDNIK 391
Query: 1168 GDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKG 1347
G++ FK+VHF YPSRK++ +LKG++L++++G +ALVG+SGCGKST V L+QR YDPT G
Sbjct: 392 GNLEFKNVHFSYPSRKEVKILKGLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTDG 451
Query: 1348 RVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANA 1527
V IDG D+R +NV LRE G+VSQEPVLF TI ENI+ G E+ T D++ +A K ANA
Sbjct: 452 MVCIDGQDIRTINVRHLREITGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANA 511
Query: 1528 NDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREV 1707
DFI +LP+ + T VGE+G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E V
Sbjct: 512 YDFIMKLPNKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVV 571
Query: 1708 QGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXX 1887
Q ALD+A+ GRTTI++AHRLST+RN D I F G IVE G+H+ELM ++GI++ +
Sbjct: 572 QVALDKARKGRTTIVIAHRLSTVRNADVIAGFDDGVIVEKGNHDELMKEKGIYFKLVTMQ 631
Query: 1888 X---------XXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLA--EEVE 2034
+E + +S S + +L E++
Sbjct: 632 TRGNEIELENATGESKSESDALEMSPKDSGSSLIKRRSTRRSIHAPQGQDRKLGTKEDLN 691
Query: 2035 ECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQ--M 2208
E PP S ++I K N + + + P F+++++ I +++ D
Sbjct: 692 E-NVPPVSFWRILKLNSTEWPYFVVGIFCAIINGGLQPAFSIIFSRIIGIFTRDEDPETK 750
Query: 2209 QANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLR 2388
+ N + +F+++GI F+ FF G+ GE LT +LR+ F+++LRQD++++DD +
Sbjct: 751 RQNSNMFSVLFLVLGIISFITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPK 810
Query: 2389 HGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXX 2565
+ TG L TR A DA V+ + +RL V+ +I + + I YGWQ
Sbjct: 811 NTTGALTTRLANDAAQVKGAIGSRLAVITQNIANLGTGIIISLIYGWQLTLLLLAIVPII 870
Query: 2566 XMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPF 2745
+ G EM+M G+ ++D + LE AGK+A++A+E+ RTV SL R+++F + Y + L+ P+
Sbjct: 871 AIAGVVEMKMLSGQALKDKKELEGAGKIATEAIENFRTVVSLTREQKFEYMYAQSLQVPY 930
Query: 2746 NTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMI 2925
+L+ AH +G F+ +Q++++F YA F G+ V + M DV VF AI F +
Sbjct: 931 RNSLRKAHIFGVSFSITQAMMYFSYAGCFRFGAYLVANEFMNFQDVLLVFSAIVFGAMAV 990
Query: 2926 GNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPIT--GNISIRNVFFNYPTR 3099
G +SF PD KA+++A+ + +IE IDS S G+ KP T GN++ V FNYPTR
Sbjct: 991 GQVSSFAPDYAKAKVSAAHVIMIIEKSPLIDSYSPHGL-KPNTLEGNVTFNEVVFNYPTR 1049
Query: 3100 KDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNIS 3279
D VLQG +L++K G+T+ALVG SGCGKST++ LLERFY+ G ++IDG I++LN+
Sbjct: 1050 PDIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGSVLIDGKEIKHLNVQ 1109
Query: 3280 SLREQVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDT 3456
LR + IVSQEP LFDC+I ENI YG N R V+++EIV+AAK ANIH+FI LP+ Y+T
Sbjct: 1110 WLRAHLGIVSQEPILFDCSIAENIAYGDNSRVVSHEEIVQAAKEANIHHFIETLPEKYNT 1169
Query: 3457 HVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTC 3636
VG+KGTQLSGGQKQRIAIARALVR P +LLLDEATSALDTESEK+VQEALD A++GRTC
Sbjct: 1170 RVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTC 1229
Query: 3637 LVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
+VIAHRLSTIQN+D+I + GK+ E GTH +L+ + IY Q
Sbjct: 1230 IVIAHRLSTIQNADLIVVFQNGKVKEHGTHQQLLAQKGIYFSMVSVQ 1276
>gi|6755048|ref|NP_035206.1| ATP-binding cassette, sub-family B
(MDR/TAP), member 1A; P glycoprotein 3; ATP-binding
cassette, sub-family B (MDR/TAP), member 4; multi-drug
resistance 3; P-glycoprotein; multiple drug resistant 1a
[Mus musculus]
gi|387427|gb|AAA39514.1| P-glycoprotein
Length = 1276
Score = 1038 bits (2684), Expect = 0.0
Identities = 556/1239 (44%), Positives = 782/1239 (62%), Gaps = 17/1239 (1%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVN-PE 288
+F Y +D L ++ GT+AA+IHG PL+ ++ G MT F N V ++ N E
Sbjct: 38 MFRYAGWLDRLYMLVGTLAAIIHGVALPLMMLIFGDMTDSFASVGN----VSKNSTNMSE 93
Query: 289 GLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILR 468
+ E+ Y YY +G + +Y+Q++ + A R +HK+RQ + AI+
Sbjct: 94 ADKRAMFAKLEEEMTTYAYYYTGIGAGVLIVAYIQVSFWCLAAGRQIHKIRQKFFHAIMN 153
Query: 469 QQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLV 648
Q+I WFD G L RLTDD+ ++ EG+GDK + Q A F G+ +GF W +TLV
Sbjct: 154 QEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQAMATFFGGFIIGFTRGWKLTLV 213
Query: 649 MMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRF 828
++ +P++ LS +K +++ T E YA AGA+AEE ++IRTV + G K+EL+R+
Sbjct: 214 ILAISPVLGLSAGIWAKILSSFTDKELHAYAKAGAVAEEVLAAIRTVIAFGGQKKELERY 273
Query: 829 YNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFF 1008
N LE ++ GI K I +G + L +Y+SYALAFWYG++L+I+ + G + TVFF
Sbjct: 274 NNNLEEAKRLGIKKAITANISMGAAFLLIYASYALAFWYGTSLVISKE-YSIGQVLTVFF 332
Query: 1009 AVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKD 1188
+VL G+ S+G A P++ +F ARGAA V ++I++ P ID +S G DN++G++ FK+
Sbjct: 333 SVLIGAFSVGQASPNIEAFANARGAAYEVFKIIDNKPSIDSFSKSGHKPDNIQGNLEFKN 392
Query: 1189 VHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGV 1368
+HF YPSRK++ +LKG++L++K+G +ALVG+SGCGKST V L+QR YDP G V IDG
Sbjct: 393 IHFSYPSRKEVQILKGLNLKVKSGQTVALVGNSGCGKSTTVQLMQRLYDPLDGMVSIDGQ 452
Query: 1369 DLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRL 1548
D+R +NV LRE IG+VSQEPVLF TI ENI+ G E T D++ +A K ANA DFI +L
Sbjct: 453 DIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGREDVTMDEIEKAVKEANAYDFIMKL 512
Query: 1549 PDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQA 1728
P + T VGE+G +SGGQKQRIAIARALV+NPKILLLDEATSALDTE+E VQ ALD+A
Sbjct: 513 PHQFDTLVGERGAHVSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKA 572
Query: 1729 QAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXX 1908
+ GRTTI++AHRLST+RN D I F G IVE G+H+ELM ++GI++ +
Sbjct: 573 REGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHDELMREKGIYFKLVMTQTAGNEIE 632
Query: 1909 ---EA--GKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKA-----PPTS 2058
EA KD D + S+ H ++ +A PP S
Sbjct: 633 LGNEACKSKDEIDNLDMSSKDSGSSLIRRRSTRKSICGPHDQDRKLSTKEALDEDVPPAS 692
Query: 2059 MFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSL--PADQMQANVYFWC 2232
++I K N + + + P F+++++++ V++ P + + N +
Sbjct: 693 FWRILKLNSTEWPYFVVGIFCAIINGGLQPAFSVIFSKVVGVFTNGGPPETQRQNSNLFS 752
Query: 2233 GMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCT 2412
+F+++GI F+ FF G+ GE LT +LR+ FK++LRQD++++DD ++ TG L T
Sbjct: 753 LLFLILGIISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDDPKNTTGALTT 812
Query: 2413 RFATDAPNVRYVF-TRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEM 2589
R A DA V+ +RL V+ +I + + I YGWQ + G EM
Sbjct: 813 RLANDAAQVKGATGSRLAVIFQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAIAGVVEM 872
Query: 2590 QMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAH 2769
+M G+ ++D + LE +GK+A++A+E+ RTV SL R+++F Y + L+ P+ +K AH
Sbjct: 873 KMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNAMKKAH 932
Query: 2770 TYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIP 2949
+G F+F+Q++++F YAA F G+ V QQ M +V VF AI F +G +SF P
Sbjct: 933 VFGITFSFTQAMMYFSYAACFRFGAYLVTQQLMTFENVLLVFSAIVFGAMAVGQVSSFAP 992
Query: 2950 DVVKARLAASLLFYLIEHPTPIDSLSDSGIVKP--ITGNISIRNVFFNYPTRKDTKVLQG 3123
D KA ++AS + +IE IDS S G+ KP + GN+ V FNYPTR VLQG
Sbjct: 993 DYAKATVSASHIIRIIEKTPEIDSYSTQGL-KPNMLEGNVQFSGVVFNYPTRPSIPVLQG 1051
Query: 3124 FTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCI 3303
+L++K G+T+ALVG SGCGKST++ LLERFY+ G + +DG I+ LN+ LR Q+ I
Sbjct: 1052 LSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSVFLDGKEIKQLNVQWLRAQLGI 1111
Query: 3304 VSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQ 3480
VSQEP LFDC+I ENI YG N R V+Y+EIV AAK ANIH FI LPD Y+T VG+KGTQ
Sbjct: 1112 VSQEPILFDCSIAENIAYGDNSRVVSYEEIVRAAKEANIHQFIDSLPDKYNTRVGDKGTQ 1171
Query: 3481 LSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLS 3660
LSGGQKQRIAIARALVR P +LLLDEATSALDTESEK+VQEALD A++GRTC+VIAHRLS
Sbjct: 1172 LSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLS 1231
Query: 3661 TIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
TIQN+D+I ++ GK+ E GTH +L+ + IY Q
Sbjct: 1232 TIQNADLIVVIQNGKVKEHGTHQQLLAQKGIYFSMVSVQ 1270
>gi|266517|sp|P21447|MDR3_MOUSE Multidrug resistance protein 3
(P-glycoprotein 3) (MDR1A)
gi|110720|pir||A34786 multidrug resistance protein 1a - mouse
gi|387429|gb|AAA39517.1| multidrug resistance protein
Length = 1276
Score = 1038 bits (2684), Expect = 0.0
Identities = 557/1239 (44%), Positives = 781/1239 (62%), Gaps = 17/1239 (1%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVN-PE 288
+F Y +D L ++ GT+AA+IHG PL+ ++ G MT F N V ++ N E
Sbjct: 38 MFRYAGWLDRLYMLVGTLAAIIHGVALPLMMLIFGDMTDSFASVGN----VSKNSTNMSE 93
Query: 289 GLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILR 468
+ E+ Y YY +G + +Y+Q++ + A R +HK+RQ + AI+
Sbjct: 94 ADKRAMFAKLEEEMTTYAYYYTGIGAGVLIVAYIQVSFWCLAAGRQIHKIRQKFFHAIMN 153
Query: 469 QQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLV 648
Q+I WFD G L RLTDD+ ++ EG+GDK + Q A F G+ +GF W +TLV
Sbjct: 154 QEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQAMATFFGGFIIGFTRGWKLTLV 213
Query: 649 MMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRF 828
++ +P++ LS +K +++ T E YA AGA+AEE ++IRTV + G K+EL+R+
Sbjct: 214 ILAISPVLGLSAGIWAKILSSFTDKELHAYAKAGAVAEEVLAAIRTVIAFGGQKKELERY 273
Query: 829 YNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFF 1008
N LE ++ GI K I +G + L +Y+SYALAFWYG++L+I+ + G + TVFF
Sbjct: 274 NNNLEEAKRLGIKKAITANISMGAAFLLIYASYALAFWYGTSLVISKE-YSIGQVLTVFF 332
Query: 1009 AVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKD 1188
+VL G+ S+G A P++ +F ARGAA V ++I++ P ID +S G DN++G++ FK+
Sbjct: 333 SVLIGAFSVGQASPNIEAFANARGAAYEVFKIIDNKPSIDSFSKSGHKPDNIQGNLEFKN 392
Query: 1189 VHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGV 1368
+HF YPSRK++ +LKG++L++K+G +ALVG+SGCGKST V L+QR YDP G V IDG
Sbjct: 393 IHFSYPSRKEVQILKGLNLKVKSGQTVALVGNSGCGKSTTVQLMQRLYDPLDGMVSIDGQ 452
Query: 1369 DLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRL 1548
D+R +NV LRE IG+VSQEPVLF TI ENI+ G E T D++ +A K ANA DFI +L
Sbjct: 453 DIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGREDVTMDEIEKAVKEANAYDFIMKL 512
Query: 1549 PDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQA 1728
P + T VGE+G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E VQ ALD+A
Sbjct: 513 PHQFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKA 572
Query: 1729 QAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXX 1908
+ GRTTI++AHRLST+RN D I F G IVE G+H+ELM ++GI++ +
Sbjct: 573 REGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHDELMREKGIYFKLVMTQTAGNEIE 632
Query: 1909 ---EA--GKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKA-----PPTS 2058
EA KD D + S+ H ++ +A PP S
Sbjct: 633 LGNEACKSKDEIDNLDMSSKDSGSSLIRRRSTRKSICGPHDQDRKLSTKEALDEDVPPAS 692
Query: 2059 MFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSL--PADQMQANVYFWC 2232
++I K N + + + P F+++++++ V++ P + + N +
Sbjct: 693 FWRILKLNSTEWPYFVVGIFCAIINGGLQPAFSVIFSKVVGVFTNGGPPETQRQNSNLFS 752
Query: 2233 GMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCT 2412
+F+++GI F+ FF G+ GE LT +LR+ FK++LRQD++++DD ++ TG L T
Sbjct: 753 LLFLILGIISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDDPKNTTGALTT 812
Query: 2413 RFATDAPNVRYVF-TRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEM 2589
R A DA V+ +RL V+ +I + + I YGWQ + G EM
Sbjct: 813 RLANDAAQVKGATGSRLAVIFQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAIAGVVEM 872
Query: 2590 QMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAH 2769
+M G+ ++D + LE +GK+A++A+E+ RTV SL R+++F Y + L+ P+ +K AH
Sbjct: 873 KMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNAMKKAH 932
Query: 2770 TYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIP 2949
+G F F+Q++++F YAA F G+ V QQ M +V VF AI F +G +SF P
Sbjct: 933 VFGITFFFTQAMMYFSYAACFRFGAYLVTQQLMTFENVLLVFSAIVFGAMAVGQVSSFAP 992
Query: 2950 DVVKARLAASLLFYLIEHPTPIDSLSDSGIVKP--ITGNISIRNVFFNYPTRKDTKVLQG 3123
D KA ++AS + +IE IDS S G+ KP + GN+ FNYPTR VLQG
Sbjct: 993 DYAKATVSASHIIRIIEKTPEIDSYSTQGL-KPNMLEGNVQFSGFVFNYPTRPSIPVLQG 1051
Query: 3124 FTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCI 3303
+L++K G+T+ALVG SGCGKST++ LLERFY+ G + +DG I+ LN+ LR Q+ I
Sbjct: 1052 LSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSVFLDGKEIKQLNVQWLRAQLGI 1111
Query: 3304 VSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQ 3480
VSQEP LFDC+I ENI YG N R V+Y+EIV AAK ANIH FI LPD Y+T VG+KGTQ
Sbjct: 1112 VSQEPILFDCSIAENIAYGDNSRVVSYEEIVRAAKEANIHQFIDSLPDKYNTRVGDKGTQ 1171
Query: 3481 LSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLS 3660
LSGGQKQRIAIARALVR P +LLLDEATSALDTESEK+VQEALD A++GRTC+VIAHRLS
Sbjct: 1172 LSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLS 1231
Query: 3661 TIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
TIQN+D+I ++ GK+ E GTH +L+ + IY Q
Sbjct: 1232 TIQNADLIVVIQNGKVKEHGTHQQLLAQKGIYFSMVSVQ 1270
>gi|833699|gb|AAA75000.1| multidrug resistance protein
gi|1098061|prf||2115220A P-glycoprotein
Length = 1287
Score = 1037 bits (2682), Expect = 0.0
Identities = 563/1236 (45%), Positives = 780/1236 (62%), Gaps = 15/1236 (1%)
Frame = +1
Query: 94 KLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVD 273
K+ + +F Y+ D +L++ GT+A++ HGA PL+ +V G MT F+ D
Sbjct: 48 KVGVFTMFRYSSTSDKMLMLFGTIASLAHGAALPLMMLVFGEMTDSFVNVGQVD----TG 103
Query: 274 NVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYL 453
N E ++ S E ++ Y YY LG + +Y+QI+ + A R + K+R N+
Sbjct: 104 NFTWESMINASR-ELQGQMTTYAYYYSGLGFGVMLCAYIQISFWTLSAGRQIKKIRSNFF 162
Query: 454 KAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSW 633
A+LRQ+I WFD G L RLTDD+ ++ EG+GDK A+L+Q + G+ +GF W
Sbjct: 163 HAVLRQEIGWFDINDAGELNTRLTDDVSKINEGIGDKIAMLLQSLTTLVTGFIIGFIKGW 222
Query: 634 SMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKR 813
+T VM +P++ LS A +K ++ T E + YA AGA+AEE SSIRTV + G +
Sbjct: 223 KLTWVMGAISPIMGLSAAIWAKVLSAFTNKELKAYAKAGAVAEEVLSSIRTVFAFGGQNK 282
Query: 814 ELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLI 993
E+ R+ LE ++ GI K + +GF+ L +Y++Y+LAFWYG+TLII D + G +
Sbjct: 283 EIHRYEKNLEDAKKIGIKKAITANVSIGFAFLMIYAAYSLAFWYGTTLII-DGGYTIGSV 341
Query: 994 FTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGD 1173
TVFFAV+ G+ ++G P++ +F ARGAA T+ +I++ PKID +S EG+ D +KGD
Sbjct: 342 LTVFFAVIIGAFAVGQTSPNIEAFANARGAAYTIFNIIDNQPKIDSFSKEGLKPDKIKGD 401
Query: 1174 ISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRV 1353
I FK+V F YPSRKDI VLKG++L + +G +ALVGSSGCGKST V L+QRFYDP G +
Sbjct: 402 IEFKNVIFTYPSRKDIQVLKGLNLNIPSGKTVALVGSSGCGKSTTVQLIQRFYDPEDGVI 461
Query: 1354 LIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAND 1533
+DG D+R +N+ LRE IG+VSQEP+LFD TI +NI+ G E T +++ A K ANA D
Sbjct: 462 TLDGQDIRSLNIRYLREIIGVVSQEPILFDTTIADNIRYGREDVTKEEIERATKEANAYD 521
Query: 1534 FIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQG 1713
FI +LPD T VGE+G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E VQ
Sbjct: 522 FIMKLPDKLETLVGERGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQS 581
Query: 1714 ALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXX 1893
ALD+A+ GRTTI+VAHRLSTIRN + I F G IVE GSH+ELM + G+++++
Sbjct: 582 ALDKAREGRTTIVVAHRLSTIRNANAIAGFDNGVIVEQGSHKELMERGGVYFNLV-TLQT 640
Query: 1894 XXXXXEAGKDIEDTISES----AHSHLXXXXXXXXXXXXXXXIHQL-------AEEVEEC 2040
+ +D+E I E H+H + + E+ +E
Sbjct: 641 VETSKDTEEDLETHIYEKKIPVTHTHSNLVRRKSSRNTIKSKVPETEDKEVDEEEKKKEE 700
Query: 2041 KAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANV 2220
PP S FK+ K N + + + P FA++++ I V++ P QM++
Sbjct: 701 GPPPVSFFKVMKLNKPEWPYFVVGVICAMINGATQPAFAIIFSRIIGVFAGPVSQMRSES 760
Query: 2221 YFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTG 2400
+ +F+ +G F+ FF G+ GE LTM+LR +FK++LRQ+I ++DD ++ TG
Sbjct: 761 SMYSLLFLALGGVSFITFFLQGFTFGKAGEILTMRLRLGSFKSMLRQEIGWFDDSKNSTG 820
Query: 2401 KLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGG 2577
L TR ATDA V+ TRL ++ ++ + A+ I F YGWQ G
Sbjct: 821 ALTTRLATDASQVQGATGTRLALLAQNVANLGTAIIISFIYGWQLTLLILAIVPVIAAAG 880
Query: 2578 YFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNL 2757
EM+M G +D + LE+AGK+++ AV +IRTV SL R+ +F Y + L P+ ++
Sbjct: 881 LVEMKMFAGHAKKDKKELEKAGKISTDAVLNIRTVVSLTRERKFEAMYEKSLEGPYRNSI 940
Query: 2758 KHAHTYGAVFAFSQSLIFFMYAAAF-YLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNT 2934
K AH +G + SQ+ F LG+ V + M+ +V+ V AI +G T
Sbjct: 941 KKAHLHGLTYGLSQAHHVLCLCWVFSVLGAYLVVEGLMKLDEVFLVSSAIVLGAMALGQT 1000
Query: 2935 TSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTK 3111
+SF PD KA ++A+ +F L+E IDS SD G K +GN+ + V FNYPTR D
Sbjct: 1001 SSFAPDYTKAMISAAHIFSLLERVPQIDSYSDQGEKPKNCSGNVVFKGVNFNYPTRPDIT 1060
Query: 3112 VLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLRE 3291
VLQG + +K G+T+ALVG SGCGKST + LLERFY+ +G +++DG ++RNLNI +R
Sbjct: 1061 VLQGLDISVKQGETLALVGSSGCGKSTTVSLLERFYDPFEGEVLVDGLSVRNLNIQWVRA 1120
Query: 3292 QVCIVSQEPTLFDCTIGENICYG-TNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGE 3468
Q+ IVSQEP LFDC+IG+NI YG NR VT +EI AAK ANIH+FI L D Y+T VG+
Sbjct: 1121 QMGIVSQEPILFDCSIGDNIAYGDNNRKVTQEEIETAAKEANIHSFIESLTDKYNTRVGD 1180
Query: 3469 KGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIA 3648
KGTQLSGGQKQRIAIARAL+R P +LLLDEATSALDTESEK+VQEALD A+ GRTC+VIA
Sbjct: 1181 KGTQLSGGQKQRIAIARALIRKPKILLLDEATSALDTESEKVVQEALDKARMGRTCIVIA 1240
Query: 3649 HRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIY 3756
HRLSTIQN+D IA++ GK+VE+GTH +L++ +Y
Sbjct: 1241 HRLSTIQNADKIAVIQNGKVVEQGTHQQLLQLKGVY 1276
Score = 395 bits (1015), Expect = e-108
Identities = 227/579 (39%), Positives = 333/579 (57%), Gaps = 4/579 (0%)
Frame = +1
Query: 151 ITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEV 330
+ G + A+I+GA P AI+ + VF P+S + SE
Sbjct: 722 VVGVICAMINGATQPAFAIIFSRIIGVFAG-------------------PVS--QMRSES 760
Query: 331 VKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD--KQQTG 504
Y + +L LG + F T ++Q F E L +LR K++LRQ+I WFD K TG
Sbjct: 761 SMYSLLFLALGGVSFITFFLQGFTFGKAGEILTMRLRLGSFKSMLRQEIGWFDDSKNSTG 820
Query: 505 NLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSG 684
LT RL D +V+ G + ALL Q A + F Y W +TL+++ P+I +G
Sbjct: 821 ALTTRLATDASQVQGATGTRLALLAQNVANLGTAIIISFIYGWQLTLLILAIVPVIAAAG 880
Query: 685 AKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGI 864
K A + +++ AG I+ + +IRTV SL ++ + +LE + I
Sbjct: 881 LVEMKMFAGHAKKDKKELEKAGKISTDAVLNIRTVVSLTRERKFEAMYEKSLEGPYRNSI 940
Query: 865 VKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGA 1044
K G+ G S F ++ + +F V A++ G+ +LG
Sbjct: 941 KKAHLHGLTYGLSQAHHVLCLCWVFSVLGAYLVVEGLMKLDEVFLVSSAIVLGAMALGQT 1000
Query: 1045 LPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIH 1224
+ A +A+ + ++ P+ID YS +G N G++ FK V+F YP+R DI
Sbjct: 1001 SSFAPDYTKAMISAAHIFSLLERVPQIDSYSDQGEKPKNCSGNVVFKGVNFNYPTRPDIT 1060
Query: 1225 VLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLRE 1404
VL+G+ + +K G+ +ALVGSSGCGKST V+LL+RFYDP +G VL+DG+ +R +N+ +R
Sbjct: 1061 VLQGLDISVKQGETLALVGSSGCGKSTTVSLLERFYDPFEGEVLVDGLSVRNLNIQWVRA 1120
Query: 1405 QIGIVSQEPVLFDGTIYENIKMG--NEHATHDQVVEACKMANANDFIKRLPDGYGTRVGE 1578
Q+GIVSQEP+LFD +I +NI G N T +++ A K AN + FI+ L D Y TRVG+
Sbjct: 1121 QMGIVSQEPILFDCSIGDNIAYGDNNRKVTQEEIETAAKEANIHSFIESLTDKYNTRVGD 1180
Query: 1579 KGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVA 1758
KG QLSGGQKQRIAIARAL++ PKILLLDEATSALDTE+E+ VQ ALD+A+ GRT I++A
Sbjct: 1181 KGTQLSGGQKQRIAIARALIRKPKILLLDEATSALDTESEKVVQEALDKARMGRTCIVIA 1240
Query: 1759 HRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM 1875
HRLSTI+N D+I V + G +VE G+H++L+ +G+++ +
Sbjct: 1241 HRLSTIQNADKIAVIQNGKVVEQGTHQQLLQLKGVYFSL 1279
Score = 352 bits (904), Expect = 3e-95
Identities = 215/536 (40%), Positives = 312/536 (58%), Gaps = 5/536 (0%)
Frame = +1
Query: 2203 QMQANVYFWCGMF--VLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFY 2376
QM Y++ G+ V++ + F+T + G + K+R F +LRQ+I ++
Sbjct: 120 QMTTYAYYYSGLGFGVMLCAYIQISFWTLS-----AGRQIK-KIRSNFFHAVLRQEIGWF 173
Query: 2377 DDLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXX 2553
D + G+L TR D + + ++ ++L S+ T+ IGF GW+
Sbjct: 174 DI--NDAGELNTRLTDDVSKINEGIGDKIAMLLQSLTTLVTGFIIGFIKGWKLTWVMGAI 231
Query: 2554 XXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYL 2733
+ ++ ++ + +AG VA + + IRTV + Q + Y + L
Sbjct: 232 SPIMGLSAAIWAKVLSAFTNKELKAYAKAGAVAEEVLSSIRTVFAFGGQNKEIHRYEKNL 291
Query: 2734 REPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFC 2913
+ +K A T F+ +I+ Y+ AF+ G+ + V VFFA+
Sbjct: 292 EDAKKIGIKKAITANVSIGFAFLMIYAAYSLAFWYGTTLIIDGGYTIGSVLTVFFAVIIG 351
Query: 2914 GQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKP--ITGNISIRNVFFN 3087
+G T+ I AR AA +F +I++ IDS S G+ KP I G+I +NV F
Sbjct: 352 AFAVGQTSPNIEAFANARGAAYTIFNIIDNQPKIDSFSKEGL-KPDKIKGDIEFKNVIFT 410
Query: 3088 YPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRN 3267
YP+RKD +VL+G L+I +GKTVALVG SGCGKST + L++RFY+ + G+I +DG +IR+
Sbjct: 411 YPSRKDIQVLKGLNLNIPSGKTVALVGSSGCGKSTTVQLIQRFYDPEDGVITLDGQDIRS 470
Query: 3268 LNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDG 3447
LNI LRE + +VSQEP LFD TI +NI YG +VT +EI A K AN ++FI+ LPD
Sbjct: 471 LNIRYLREIIGVVSQEPILFDTTIADNIRYG-REDVTKEEIERATKEANAYDFIMKLPDK 529
Query: 3448 YDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQG 3627
+T VGE+GTQLSGGQKQRIAIARALVR+P +LLLDEATSALDTESE +VQ ALD A++G
Sbjct: 530 LETLVGERGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQSALDKAREG 589
Query: 3628 RTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRIVESQ 3795
RT +V+AHRLSTI+N++ IA G IVE+G+H EL+ + +Y Q + S+
Sbjct: 590 RTTIVVAHRLSTIRNANAIAGFDNGVIVEQGSHKELMERGGVYFNLVTLQTVETSK 645
>gi|8926217|gb|AAF81747.1| his-tagged-multidrug resistance
glycoprotein MDR1 [synthetic construct]
Length = 1287
Score = 1037 bits (2682), Expect = 0.0
Identities = 554/1247 (44%), Positives = 795/1247 (63%), Gaps = 20/1247 (1%)
Frame = +1
Query: 97 LTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRA---QNSDFVVG 267
++ + +F Y+ +D L ++ GT+AA+IHGA PL+ +V G MT F A +N F V
Sbjct: 40 VSTFAMFRYSNWLDRLYMLVGTMAAIIHGAALPLMMLVFGNMTDSFANAGISRNKTFPV- 98
Query: 268 VDNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQN 447
+ N + ++ E+ Y YY +G + +Y+Q++ + A R + K+R+
Sbjct: 99 IINESITNNTQHFINHLEEEMTTYAYYYSGIGAGVLVAAYIQVSFWCLAAGRQILKIRKQ 158
Query: 448 YLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFY 627
+ AI+RQ+I WFD G L RLTDD+ ++ EG+GDK + Q A F G+ VGF
Sbjct: 159 FFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQSIATFFTGFIVGFTR 218
Query: 628 SWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGH 807
W +TLV++ +P++ LS A +K +++ T E YA AGA+AEE ++IRTV + G
Sbjct: 219 GWKLTLVILAISPVLGLSAAIWAKILSSFTDKELLAYAKAGAVAEEVLAAIRTVIAFGGQ 278
Query: 808 KRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRG 987
K+EL+R+ LE ++ GI K I +G + L +Y+SYALAFWYG++L+++ + G
Sbjct: 279 KKELERYNKNLEEAKRIGIKKAITANISIGAAFLLIYASYALAFWYGTSLVLSSE-YSIG 337
Query: 988 LIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMK 1167
+ TVFF+VL G+ S+G A P + +F ARGAA + ++I++ P ID YS G DN+K
Sbjct: 338 QVLTVFFSVLIGAFSIGQASPSIEAFANARGAAYEIFKIIDNKPSIDSYSKSGHKPDNIK 397
Query: 1168 GDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKG 1347
G++ FK+VHF YPSRK++ +LKG++L++++G +ALVG+SGCGKST V L+QR YDPT G
Sbjct: 398 GNLEFKNVHFSYPSRKEVKILKGLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTDG 457
Query: 1348 RVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANA 1527
V IDG D+R +NV LRE G+VSQEPVLF TI ENI+ G E+ T D++ +A K ANA
Sbjct: 458 MVCIDGQDIRTINVRHLREITGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANA 517
Query: 1528 NDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREV 1707
DFI +LP+ + T VGE+G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E V
Sbjct: 518 YDFIMKLPNKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVV 577
Query: 1708 QGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXX 1887
Q ALD+A+ GRTTI++AHRLST+RN D I F G IVE G+H+ELM ++GI++ +
Sbjct: 578 QVALDKARKGRTTIVIAHRLSTVRNADVIAGFDDGVIVEKGNHDELMKEKGIYFKLVTMQ 637
Query: 1888 X---------XXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLA--EEVE 2034
+E + +S S + +L E++
Sbjct: 638 TRGNEIELENATGESKSESDALEMSPKDSGSSLIKRRSTRRSIHAPQGQDRKLGTKEDLN 697
Query: 2035 ECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQ--M 2208
E PP S ++I K N + + + P F+++++ I +++ D
Sbjct: 698 E-NVPPVSFWRILKLNSTEWPYFVVGIFCAIINGGLQPAFSIIFSRIIGIFTRDEDPETK 756
Query: 2209 QANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLR 2388
+ N + +F+++GI F+ FF G+ GE LT +LR+ F+++LRQD++++DD +
Sbjct: 757 RQNSNMFSVLFLVLGIISFITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPK 816
Query: 2389 HGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXX 2565
+ TG L TR A DA V+ + +RL V+ +I + + I YGWQ
Sbjct: 817 NTTGALTTRLANDAAQVKGAIGSRLAVITQNIANLGTGIIISLIYGWQLTLLLLAIVPII 876
Query: 2566 XMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPF 2745
+ G EM+M G+ ++D + LE AGK+A++A+E+ RTV SL R+++F + Y + L+ P+
Sbjct: 877 AIAGVVEMKMLSGQALKDKKELEGAGKIATEAIENFRTVVSLTREQKFEYMYAQSLQVPY 936
Query: 2746 NTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMI 2925
+L+ AH +G F+ +Q++++F YA F G+ V + M DV VF AI F +
Sbjct: 937 RNSLRKAHIFGVSFSITQAMMYFSYAGCFRFGAYLVANEFMNFQDVLLVFSAIVFGAMAV 996
Query: 2926 GNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPIT--GNISIRNVFFNYPTR 3099
G +SF PD KA+++A+ + +IE IDS S G+ KP T GN++ V FNYPTR
Sbjct: 997 GQVSSFAPDYAKAKVSAAHVIMIIEKSPLIDSYSPHGL-KPNTLEGNVTFNEVVFNYPTR 1055
Query: 3100 KDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNIS 3279
D VLQG +L++K G+T+ALVG SGCGKST++ LLERFY+ G ++IDG I++LN+
Sbjct: 1056 PDIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGSVLIDGKEIKHLNVQ 1115
Query: 3280 SLREQVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDT 3456
LR + IVSQEP LFDC+I ENI YG N R V+++EI++AAK ANIH+FI LP+ Y+T
Sbjct: 1116 WLRAHLGIVSQEPILFDCSIAENIAYGDNSRVVSHEEIMQAAKEANIHHFIETLPEKYNT 1175
Query: 3457 HVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTC 3636
VG+KGTQLSGGQKQRIAIARALVR P +LLLDEATSALDTESEK+VQEALD A++GRTC
Sbjct: 1176 RVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTC 1235
Query: 3637 LVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
+VIAHRLSTIQN+D+I + GK+ E GTH +L+ + IY Q
Sbjct: 1236 IVIAHRLSTIQNADLIVVFQNGKVKEHGTHQQLLAQKGIYFSMISVQ 1282
>gi|1362689|pir||S55692 multidrug resistance protein homolog (mdr) -
African clawed frog
Length = 1287
Score = 1037 bits (2681), Expect = 0.0
Identities = 563/1236 (45%), Positives = 780/1236 (62%), Gaps = 15/1236 (1%)
Frame = +1
Query: 94 KLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVD 273
K+ + +F Y+ D +L++ GT+A++ HGA PL+ +V G MT F+ D
Sbjct: 48 KVGVFTMFRYSSTSDKMLMLFGTIASLAHGAALPLMMLVFGEMTDSFVNVGQVD----TG 103
Query: 274 NVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYL 453
N E ++ S E ++ Y YY LG + +Y+QI+ + A R + K+R N+
Sbjct: 104 NFTWESMINASR-ELQGQMTTYAYYYSGLGFGVMLCAYIQISFWTLSAGRQIKKIRSNFF 162
Query: 454 KAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSW 633
A+LRQ+I WFD G L RLTDD+ ++ EG+GDK A+L+Q + G+ +GF W
Sbjct: 163 HAVLRQEIGWFDINDAGELNTRLTDDVSKINEGIGDKIAMLLQSLTTLVTGFIIGFIKGW 222
Query: 634 SMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKR 813
+T VM +P++ LS A +K ++ T E + YA AGA+AEE SSIRTV + G +
Sbjct: 223 KLTWVMGAISPIMGLSAAIWAKVLSAFTNKELKAYAKAGAVAEEVLSSIRTVFAFGGQNK 282
Query: 814 ELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLI 993
E+ R+ LE ++ GI K + +GF+ L +Y++Y+LAFWYG+TLII D + G +
Sbjct: 283 EIHRYEKNLEDAKKIGIKKAITANVSIGFAFLMIYAAYSLAFWYGTTLII-DGGYTIGSV 341
Query: 994 FTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGD 1173
TVFFAV+ G+ ++G P++ +F ARGAA T+ +I++ PKID +S EG+ D +KGD
Sbjct: 342 LTVFFAVIIGAFAVGQTSPNIEAFANARGAAYTIFNIIDNQPKIDSFSKEGLKPDKIKGD 401
Query: 1174 ISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRV 1353
I FK+V F YPSRKDI VLKG++L + +G +ALVGSSGCGKST V L+QRFYDP G +
Sbjct: 402 IEFKNVIFTYPSRKDIQVLKGLNLNIPSGKTVALVGSSGCGKSTTVQLIQRFYDPEDGVI 461
Query: 1354 LIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAND 1533
+DG D+R +N+ LRE IG+VSQEP+LFD TI +NI+ G E T +++ A K ANA D
Sbjct: 462 TLDGQDIRSLNIRYLREIIGVVSQEPILFDTTIADNIRYGREDVTKEEIERATKEANAYD 521
Query: 1534 FIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQG 1713
FI +LPD T VGE+G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E VQ
Sbjct: 522 FIMKLPDKLETLVGERGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQS 581
Query: 1714 ALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXX 1893
ALD+A+ GRTTI+VAHRLSTIRN + I F G IVE GSH+ELM + G+++++
Sbjct: 582 ALDKAREGRTTIVVAHRLSTIRNANAIAGFDNGVIVEQGSHKELMERGGVYFNLV-TLQT 640
Query: 1894 XXXXXEAGKDIEDTISES----AHSHLXXXXXXXXXXXXXXXIHQL-------AEEVEEC 2040
+ +D+E I E H+H + + E+ +E
Sbjct: 641 VETSKDTEEDLETHIYEKKIPVTHTHSNLVRRKSSRNTIKSKVPETEDKEVDEEEKKKEE 700
Query: 2041 KAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANV 2220
PP S FK+ K N + + + P FA++++ I V++ P QM++
Sbjct: 701 GPPPVSFFKVMKLNKPEWPYFVVGVICAMINGATQPAFAIIFSRIIGVFAGPVSQMRSES 760
Query: 2221 YFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTG 2400
+ +F+ +G F+ FF G+ GE LTM+LR +FK++LRQ+I ++DD ++ TG
Sbjct: 761 SMYSLLFLALGGVSFITFFLQRFTFGKAGEILTMRLRLGSFKSMLRQEIGWFDDSKNSTG 820
Query: 2401 KLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGG 2577
L TR ATDA V+ TRL ++ ++ + A+ I F YGWQ G
Sbjct: 821 ALTTRLATDASQVQGATGTRLALLAQNVANLGTAIIISFIYGWQLTLLILAIVPVIAAAG 880
Query: 2578 YFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNL 2757
EM+M G +D + LE+AGK+++ AV +IRTV SL R+ +F Y + L P+ ++
Sbjct: 881 LVEMKMFAGHAKKDKKELEKAGKISTDAVLNIRTVVSLTRERKFEAMYEKSLEGPYRNSI 940
Query: 2758 KHAHTYGAVFAFSQSLIFFMYAAAF-YLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNT 2934
K AH +G + SQ+ F LG+ V + M+ +V+ V AI +G T
Sbjct: 941 KKAHLHGLTYGLSQAHHVLCLCWVFSVLGAYLVVEGLMKLDEVFLVSSAIVLGAMALGQT 1000
Query: 2935 TSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTK 3111
+SF PD KA ++A+ +F L+E IDS SD G K +GN+ + V FNYPTR D
Sbjct: 1001 SSFAPDYTKAMISAAHIFSLLERVPQIDSYSDQGEKPKNCSGNVVFKGVNFNYPTRPDIT 1060
Query: 3112 VLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLRE 3291
VLQG + +K G+T+ALVG SGCGKST + LLERFY+ +G +++DG ++RNLNI +R
Sbjct: 1061 VLQGLDISVKQGETLALVGSSGCGKSTTVSLLERFYDPFEGEVLVDGLSVRNLNIQWVRA 1120
Query: 3292 QVCIVSQEPTLFDCTIGENICYG-TNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGE 3468
Q+ IVSQEP LFDC+IG+NI YG NR VT +EI AAK ANIH+FI L D Y+T VG+
Sbjct: 1121 QMGIVSQEPILFDCSIGDNIAYGDNNRKVTQEEIETAAKEANIHSFIESLTDKYNTRVGD 1180
Query: 3469 KGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIA 3648
KGTQLSGGQKQRIAIARAL+R P +LLLDEATSALDTESEK+VQEALD A+ GRTC+VIA
Sbjct: 1181 KGTQLSGGQKQRIAIARALIRKPKILLLDEATSALDTESEKVVQEALDKARMGRTCIVIA 1240
Query: 3649 HRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIY 3756
HRLSTIQN+D IA++ GK+VE+GTH +L++ +Y
Sbjct: 1241 HRLSTIQNADKIAVIQNGKVVEQGTHQQLLQLKGVY 1276
Score = 395 bits (1016), Expect = e-108
Identities = 227/579 (39%), Positives = 333/579 (57%), Gaps = 4/579 (0%)
Frame = +1
Query: 151 ITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEV 330
+ G + A+I+GA P AI+ + VF P+S + SE
Sbjct: 722 VVGVICAMINGATQPAFAIIFSRIIGVFAG-------------------PVS--QMRSES 760
Query: 331 VKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD--KQQTG 504
Y + +L LG + F T ++Q F E L +LR K++LRQ+I WFD K TG
Sbjct: 761 SMYSLLFLALGGVSFITFFLQRFTFGKAGEILTMRLRLGSFKSMLRQEIGWFDDSKNSTG 820
Query: 505 NLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSG 684
LT RL D +V+ G + ALL Q A + F Y W +TL+++ P+I +G
Sbjct: 821 ALTTRLATDASQVQGATGTRLALLAQNVANLGTAIIISFIYGWQLTLLILAIVPVIAAAG 880
Query: 685 AKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGI 864
K A + +++ AG I+ + +IRTV SL ++ + +LE + I
Sbjct: 881 LVEMKMFAGHAKKDKKELEKAGKISTDAVLNIRTVVSLTRERKFEAMYEKSLEGPYRNSI 940
Query: 865 VKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGA 1044
K G+ G S F ++ + +F V A++ G+ +LG
Sbjct: 941 KKAHLHGLTYGLSQAHHVLCLCWVFSVLGAYLVVEGLMKLDEVFLVSSAIVLGAMALGQT 1000
Query: 1045 LPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIH 1224
+ A +A+ + ++ P+ID YS +G N G++ FK V+F YP+R DI
Sbjct: 1001 SSFAPDYTKAMISAAHIFSLLERVPQIDSYSDQGEKPKNCSGNVVFKGVNFNYPTRPDIT 1060
Query: 1225 VLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLRE 1404
VL+G+ + +K G+ +ALVGSSGCGKST V+LL+RFYDP +G VL+DG+ +R +N+ +R
Sbjct: 1061 VLQGLDISVKQGETLALVGSSGCGKSTTVSLLERFYDPFEGEVLVDGLSVRNLNIQWVRA 1120
Query: 1405 QIGIVSQEPVLFDGTIYENIKMG--NEHATHDQVVEACKMANANDFIKRLPDGYGTRVGE 1578
Q+GIVSQEP+LFD +I +NI G N T +++ A K AN + FI+ L D Y TRVG+
Sbjct: 1121 QMGIVSQEPILFDCSIGDNIAYGDNNRKVTQEEIETAAKEANIHSFIESLTDKYNTRVGD 1180
Query: 1579 KGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVA 1758
KG QLSGGQKQRIAIARAL++ PKILLLDEATSALDTE+E+ VQ ALD+A+ GRT I++A
Sbjct: 1181 KGTQLSGGQKQRIAIARALIRKPKILLLDEATSALDTESEKVVQEALDKARMGRTCIVIA 1240
Query: 1759 HRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM 1875
HRLSTI+N D+I V + G +VE G+H++L+ +G+++ +
Sbjct: 1241 HRLSTIQNADKIAVIQNGKVVEQGTHQQLLQLKGVYFSL 1279
Score = 352 bits (904), Expect = 3e-95
Identities = 215/536 (40%), Positives = 312/536 (58%), Gaps = 5/536 (0%)
Frame = +1
Query: 2203 QMQANVYFWCGMF--VLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFY 2376
QM Y++ G+ V++ + F+T + G + K+R F +LRQ+I ++
Sbjct: 120 QMTTYAYYYSGLGFGVMLCAYIQISFWTLS-----AGRQIK-KIRSNFFHAVLRQEIGWF 173
Query: 2377 DDLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXX 2553
D + G+L TR D + + ++ ++L S+ T+ IGF GW+
Sbjct: 174 DI--NDAGELNTRLTDDVSKINEGIGDKIAMLLQSLTTLVTGFIIGFIKGWKLTWVMGAI 231
Query: 2554 XXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYL 2733
+ ++ ++ + +AG VA + + IRTV + Q + Y + L
Sbjct: 232 SPIMGLSAAIWAKVLSAFTNKELKAYAKAGAVAEEVLSSIRTVFAFGGQNKEIHRYEKNL 291
Query: 2734 REPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFC 2913
+ +K A T F+ +I+ Y+ AF+ G+ + V VFFA+
Sbjct: 292 EDAKKIGIKKAITANVSIGFAFLMIYAAYSLAFWYGTTLIIDGGYTIGSVLTVFFAVIIG 351
Query: 2914 GQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKP--ITGNISIRNVFFN 3087
+G T+ I AR AA +F +I++ IDS S G+ KP I G+I +NV F
Sbjct: 352 AFAVGQTSPNIEAFANARGAAYTIFNIIDNQPKIDSFSKEGL-KPDKIKGDIEFKNVIFT 410
Query: 3088 YPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRN 3267
YP+RKD +VL+G L+I +GKTVALVG SGCGKST + L++RFY+ + G+I +DG +IR+
Sbjct: 411 YPSRKDIQVLKGLNLNIPSGKTVALVGSSGCGKSTTVQLIQRFYDPEDGVITLDGQDIRS 470
Query: 3268 LNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDG 3447
LNI LRE + +VSQEP LFD TI +NI YG +VT +EI A K AN ++FI+ LPD
Sbjct: 471 LNIRYLREIIGVVSQEPILFDTTIADNIRYG-REDVTKEEIERATKEANAYDFIMKLPDK 529
Query: 3448 YDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQG 3627
+T VGE+GTQLSGGQKQRIAIARALVR+P +LLLDEATSALDTESE +VQ ALD A++G
Sbjct: 530 LETLVGERGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQSALDKAREG 589
Query: 3628 RTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRIVESQ 3795
RT +V+AHRLSTI+N++ IA G IVE+G+H EL+ + +Y Q + S+
Sbjct: 590 RTTIVVAHRLSTIRNANAIAGFDNGVIVEQGSHKELMERGGVYFNLVTLQTVETSK 645
>gi|72477|pir||DVHY1C multidrug resistance protein 1 - Chinese hamster
gi|191155|gb|AAA37004.1| p-glycoprotein
Length = 1276
Score = 1036 bits (2679), Expect = 0.0
Identities = 555/1243 (44%), Positives = 785/1243 (62%), Gaps = 19/1243 (1%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQN--SDFVVGVDNV 279
+ +F Y +D L ++ GT+AA+IHG PL+ +V G MT F N ++ V
Sbjct: 36 FTMFRYAGWLDRLYMLVGTLAAIIHGVALPLMMLVFGDMTDSFASVGNIPTNATNNATQV 95
Query: 280 NPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKA 459
N + + E+ Y YY +G + +Y+Q++ + A R +HK+RQ + A
Sbjct: 96 NASDI----FGKLEEEMTTYAYYYTGIGAGVLIVAYIQVSFWCLAAGRQIHKIRQKFFHA 151
Query: 460 ILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSM 639
I+ Q+I WFD G L RLTDD+ ++ EG+GDK + Q A F G+ +GF W +
Sbjct: 152 IMNQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQAMATFFGGFIIGFTRGWKL 211
Query: 640 TLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKREL 819
TLV++ +P++ LS +K +++ T E + YA AGA+AEE ++IRTV + G K+EL
Sbjct: 212 TLVILAISPVLGLSAGIWAKILSSFTDKELQAYAKAGAVAEEVLAAIRTVIAFGGQKKEL 271
Query: 820 DRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFT 999
+R+ N LE ++ GI K I +G + L +Y+SYALAFWYG++L+I+ + G + T
Sbjct: 272 ERYNNNLEEAKRLGIKKAITANISMGAAFLLIYASYALAFWYGTSLVISKE-YSIGQVLT 330
Query: 1000 VFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDIS 1179
VFFAVL S+G A P++ +F ARGAA + +I++ P ID +S G DN+KG++
Sbjct: 331 VFFAVLIAPFSIGQASPNIEAFANARGAAYEIFNIIDNKPSIDSFSKNGYKPDNIKGNLE 390
Query: 1180 FKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLI 1359
FK++HF YPSRKD+ +LKG++L++++G +ALVG+SGCGKST V LLQR YDPT+G V I
Sbjct: 391 FKNIHFSYPSRKDVQILKGLNLKVQSGQTVALVGNSGCGKSTTVQLLQRLYDPTEGVVSI 450
Query: 1360 DGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFI 1539
DG D+R +NV LRE IG+VSQEPVLF TI ENI+ G E+ T D++ +A K ANA DFI
Sbjct: 451 DGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFI 510
Query: 1540 KRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGAL 1719
+LP + T VGE+G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E VQ AL
Sbjct: 511 MKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAAL 570
Query: 1720 DQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXX 1899
D+A+ GRTTI++AHRLST+RN D I F G IVE G+HEELM ++GI++ +
Sbjct: 571 DKAREGRTTIVIAHRLSTVRNADIIAGFDGGVIVEQGNHEELMREKGIYFKLV-MTQTAG 629
Query: 1900 XXXEAGKDIEDTISE----------SAHSHLXXXXXXXXXXXXXXXIHQLA-EEVEECKA 2046
E G ++ ++ +E SA S + +L+ +E +
Sbjct: 630 NEIELGNEVGESKNEIDNLDMSSKDSASSLIRRRSTRRSIRGPHDQDRKLSTKEALDEDV 689
Query: 2047 PPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQ--MQANV 2220
PP S ++I K N + + ++ P F+++++++ V++ D + +
Sbjct: 690 PPISFWRILKLNSSEWPYFVVGIFCAIVNGALQPAFSIIFSKVVGVFTRNTDDETKRHDS 749
Query: 2221 YFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTG 2400
+ +F+++G+ F+ FF G+ GE LT +LR+ FK++LRQD++++D+ ++ TG
Sbjct: 750 NLFSLLFLILGVISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDNPKNTTG 809
Query: 2401 KLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGG 2577
L TR A DA V+ RL V+ +I + + I YGWQ + G
Sbjct: 810 ALTTRLANDAGQVKGATGARLAVITQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAIAG 869
Query: 2578 YFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNL 2757
EM+M G+ ++D + LE +GK+A++A+E+ RTV SL R+++F Y + L+ P+ L
Sbjct: 870 VVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTREQKFENMYAQSLQIPYRNAL 929
Query: 2758 KHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTT 2937
K AH +G F+F+Q++++F YAA F G+ V ++ M +V VF AI F +G +
Sbjct: 930 KKAHVFGITFSFTQAMMYFSYAACFRFGAYLVARELMTFENVLLVFSAIVFGAMAVGQVS 989
Query: 2938 SFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPIT--GNISIRNVFFNYPTRKDTK 3111
SF PD KA+++AS + +IE IDS S G+ KP T GN+ V FNYPTR D
Sbjct: 990 SFAPDYAKAKVSASHIIMIIEKVPSIDSYSTGGL-KPNTLEGNVKFNEVVFNYPTRPDIP 1048
Query: 3112 VLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLRE 3291
VLQG L++K G+T+ALVG SGCGKST++ LLERFY+ G + +DG + LN+ LR
Sbjct: 1049 VLQGLNLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGTVFLDGKEVNQLNVQWLRA 1108
Query: 3292 QVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGE 3468
+ IVSQEP LFDC+I ENI YG N R V+ EI AAK ANIH FI LPD Y+T VG+
Sbjct: 1109 HLGIVSQEPILFDCSIAENIAYGDNSRVVSQDEIERAAKEANIHQFIESLPDKYNTRVGD 1168
Query: 3469 KGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIA 3648
KGTQLSGGQKQRIAIARALVR P +LLLDEATSALDTESEK+VQEALD A++GRTC+VIA
Sbjct: 1169 KGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIA 1228
Query: 3649 HRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
HRLSTIQN+D+I ++ GK+ E GTH +L+ + IY Q
Sbjct: 1229 HRLSTIQNADLIVVIQNGKVKEHGTHQQLLAQKGIYFSMVSVQ 1271
>gi|126928|sp|P21449|MDR2_CRIGR Multidrug resistance protein 2
(P-glycoprotein 2)
gi|191167|gb|AAA68884.1| p-glycoprotein isoform II
Length = 1276
Score = 1035 bits (2677), Expect = 0.0
Identities = 562/1234 (45%), Positives = 782/1234 (62%), Gaps = 17/1234 (1%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDF--VVGVDNV 279
+G+F Y +D L ++ GT+AAV+HG PLL +V G MT F +A+ S + + +
Sbjct: 37 FGMFRYADWLDKLYMVLGTLAAVLHGTSLPLLMLVFGNMTDSFTKAETSIWPNMTNQSEI 96
Query: 280 NPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKA 459
N ++ SL+E ++ Y YY +G + +Y+Q++ + A R ++K+RQ + A
Sbjct: 97 NNTEVISGSLEE---DMATYAYYYTGIGAGVLIVAYIQVSFWCLAAGRQINKIRQKFFHA 153
Query: 460 ILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSM 639
I+ Q+I WFD G L RLTDD+ ++ +G+GDK + Q A FLA + VGF W +
Sbjct: 154 IMNQEIGWFDVHDIGELNTRLTDDVSKINDGIGDKIGMFFQSIATFLAAFIVGFISGWKL 213
Query: 640 TLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKREL 819
TLV++ +PLI LS A +K + + T E + YA AGA+AEE ++IRTV + G +EL
Sbjct: 214 TLVILAVSPLIGLSSAMWAKVLTSFTNKELQAYAKAGAVAEEVLAAIRTVIAFGGQNKEL 273
Query: 820 DRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFT 999
+R+ LE + GI K I +G + L +Y+SYALAFWYG++L++++ + G + T
Sbjct: 274 ERYNKNLEEAKNVGIKKAVTANISIGIAYLLVYASYALAFWYGTSLVLSNE-YSVGQVLT 332
Query: 1000 VFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDIS 1179
VFF++L G+ S+G P++ F ARGAA + ++I++ P ID +S +G D++ G++
Sbjct: 333 VFFSILFGTFSIGHIAPNIEVFANARGAAYEIFKIIDNEPSIDSFSTQGHKPDSVMGNLE 392
Query: 1180 FKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLI 1359
FK+VHF YPSR I +LKG++L++++G +ALVG SGCGKST V LLQR YDPT+G V I
Sbjct: 393 FKNVHFSYPSRSGIKILKGLNLKVQSGQTVALVGKSGCGKSTTVQLLQRLYDPTEGVVSI 452
Query: 1360 DGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFI 1539
DG D+R +NV LRE IG+VSQEPVLF TI ENI+ G E+ T D++ +A K ANA DFI
Sbjct: 453 DGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFI 512
Query: 1540 KRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGAL 1719
+LP + T VGE+G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E VQ AL
Sbjct: 513 MKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAAL 572
Query: 1720 DQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIF---YDMTXXXX 1890
D+A+ GRTTI++AHRLST+RN D I F G IVE G+HEELM ++GI+ M
Sbjct: 573 DKAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHEELMKEKGIYCRLVMMQTRGN 632
Query: 1891 XXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAE------EVEECKAPP 2052
EA DTI+ S Q E E ++ P
Sbjct: 633 EVELGSEADGSQSDTIASELTSEEFKSPSVRKSTCRSICGSQDQERRVSVKEAQDEDVPL 692
Query: 2053 TSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPAD--QMQANVYF 2226
S + I K N + + + PVF++V++ I V++ D Q N
Sbjct: 693 VSFWGILKLNITEWPYLVVGVLCAVINGCMQPVFSIVFSGIIGVFTRDDDPKTKQQNCNL 752
Query: 2227 WCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKL 2406
+ F++MG+ FV +F G+ GE LT +LR+ FK++LRQDI+++DD R+ TG L
Sbjct: 753 FSLFFLVMGMICFVTYFFQGFTFGKAGEILTKRLRYMVFKSMLRQDISWFDDHRNSTGAL 812
Query: 2407 CTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYF 2583
TR A+DA NV+ + +RL + ++ + + I YGWQ + G
Sbjct: 813 TTRLASDAANVKGAMSSRLAGITQNVANLGTGIIISLVYGWQLTLLLVVIAPLIILSGMM 872
Query: 2584 EMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKH 2763
EM++ G+ ++D + LE +GK+A++A+E+ RTV SL R+++F Y + L+ P+ LK
Sbjct: 873 EMKVLSGQALKDKKELEVSGKIATEAIENFRTVVSLTREQKFENMYAQSLQIPYRNALKK 932
Query: 2764 AHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSF 2943
AH +G F+F+Q++++F YAA F G+ V Q M +V VF A+ F GN +SF
Sbjct: 933 AHVFGITFSFTQAMMYFSYAACFRFGAYLVAHQIMTFENVMLVFSAVVFGAIAAGNASSF 992
Query: 2944 IPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKP--ITGNISIRNVFFNYPTRKDTKVL 3117
PD KA+++AS + ++E IDS S G+ KP + GN+ V FNYPTR D VL
Sbjct: 993 APDYAKAKVSASHIIRIMEKIPSIDSYSTRGL-KPNWLEGNVKFNEVVFNYPTRPDIPVL 1051
Query: 3118 QGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQV 3297
QG +L++K G+T+ALVG SGCGKST++ LLERFY+ G + +DG I+ LN+ LR +
Sbjct: 1052 QGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGTVFLDGKEIKQLNVQWLRAHL 1111
Query: 3298 CIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKG 3474
IVSQEP LFDC+I ENI YG N R V+ EI AAK ANIH FI LPD Y+T VG+KG
Sbjct: 1112 GIVSQEPILFDCSIAENIAYGDNSRVVSQDEIERAAKEANIHQFIESLPDKYNTRVGDKG 1171
Query: 3475 TQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHR 3654
TQLSGGQKQRIAIARALVR P +LLLDEATSALDTESEK+VQEALD A++GRTC+VIAHR
Sbjct: 1172 TQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHR 1231
Query: 3655 LSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIY 3756
LSTIQN+D+I ++ GK+ E GTH +L+ + IY
Sbjct: 1232 LSTIQNADLIVVIQNGKVKEHGTHQQLLAQKGIY 1265
Score = 429 bits (1103), Expect = e-118
Identities = 240/581 (41%), Positives = 352/581 (60%), Gaps = 5/581 (0%)
Frame = +1
Query: 148 LITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSE 327
L+ G + AVI+G P+ +IV G+ VF R + D N N
Sbjct: 709 LVVGVLCAVINGCMQPVFSIVFSGIIGVFTR--DDDPKTKQQNCN--------------- 751
Query: 328 VVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD--KQQT 501
+ +++LV+G++ F T + Q F E L +LR K++LRQ I WFD + T
Sbjct: 752 --LFSLFFLVMGMICFVTYFFQGFTFGKAGEILTKRLRYMVFKSMLRQDISWFDDHRNST 809
Query: 502 GNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLS 681
G LT RL D V+ + + A + Q A G + Y W +TL+++ APLI+LS
Sbjct: 810 GALTTRLASDAANVKGAMSSRLAGITQNVANLGTGIIISLVYGWQLTLLLVVIAPLIILS 869
Query: 682 GAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTG 861
G K ++ + +++ V+G IA E + RTV SL ++ + + +L++ +
Sbjct: 870 GMMEMKVLSGQALKDKKELEVSGKIATEAIENFRTVVSLTREQKFENMYAQSLQIPYRNA 929
Query: 862 IVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIIND-PTFDRGLIFTVFFAVLSGSTSLG 1038
+ K GI F+ MY SYA F +G+ L+ + TF+ + VF AV+ G+ + G
Sbjct: 930 LKKAHVFGITFSFTQAMMYFSYAACFRFGAYLVAHQIMTFEN--VMLVFSAVVFGAIAAG 987
Query: 1039 GALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKD 1218
A + A+ +AS ++R++ P ID YS G+ + ++G++ F +V F YP+R D
Sbjct: 988 NASSFAPDYAKAKVSASHIIRIMEKIPSIDSYSTRGLKPNWLEGNVKFNEVVFNYPTRPD 1047
Query: 1219 IHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSL 1398
I VL+G+SLE+K G +ALVGSSGCGKST+V LL+RFYDP G V +DG +++++NV L
Sbjct: 1048 IPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGTVFLDGKEIKQLNVQWL 1107
Query: 1399 REQIGIVSQEPVLFDGTIYENIKMGNEH--ATHDQVVEACKMANANDFIKRLPDGYGTRV 1572
R +GIVSQEP+LFD +I ENI G+ + D++ A K AN + FI+ LPD Y TRV
Sbjct: 1108 RAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQDEIERAAKEANIHQFIESLPDKYNTRV 1167
Query: 1573 GEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTII 1752
G+KG QLSGGQKQRIAIARALV+ P ILLLDEATSALDTE+E+ VQ ALD+A+ GRT I+
Sbjct: 1168 GDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIV 1227
Query: 1753 VAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM 1875
+AHRLSTI+N D I V + G + E G+H++L++++GI++ M
Sbjct: 1228 IAHRLSTIQNADLIVVIQNGKVKEHGTHQQLLAQKGIYFSM 1268
>gi|1170902|sp|P43245|MDR1_RAT Multidrug resistance protein 1
(P-glycoprotein 1)
gi|92489|pir||JH0502 p-glycoprotein - rat
Length = 1277
Score = 1035 bits (2675), Expect = 0.0
Identities = 558/1237 (45%), Positives = 792/1237 (63%), Gaps = 20/1237 (1%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNP 285
+G+F Y +D L + GT+AA+IHG PLL +V G MT F +++ + N +
Sbjct: 35 FGMFRYADWLDKLCMALGTLAAIIHGTLLPLLMLVFGYMTDSFTPSRDPHSDRAITNQSE 94
Query: 286 -EGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAI 462
+S ++ Y YY +G + +Y+Q++ + A R +HK+RQ + AI
Sbjct: 95 INSTHTVSDTSLEEDMAMYAYYYTGIGAGVLIVAYIQVSLWCLAAGRQIHKIRQKFFHAI 154
Query: 463 LRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMT 642
+ Q+I WFD G L RLTDD+ ++ +G+GDK + Q F AG+ +GF W +T
Sbjct: 155 MNQEIGWFDVNDAGELNTRLTDDVSKINDGIGDKLGMFFQSITTFSAGFIIGFISGWKLT 214
Query: 643 LVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELD 822
LV++ +PLI LS A +K + + T E + YA AGA+AEE ++IRTV + G K+EL+
Sbjct: 215 LVILAVSPLIGLSSAMWAKVLTSFTNKELQAYAKAGAVAEEVLAAIRTVIAFGGQKKELE 274
Query: 823 RFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTV 1002
R+ LE ++ GI K I +G + L +Y+SYALAFWYG++L++++ + G + TV
Sbjct: 275 RYNKNLEEAKRVGIKKAITANISIGIAYLLVYASYALAFWYGTSLVLSNE-YSIGQVLTV 333
Query: 1003 FFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISF 1182
FF++L G+ S+G P++ +F ARGAA + ++I++ P ID +S +G D++ G++ F
Sbjct: 334 FFSILLGTFSIGHLAPNIEAFANARGAAYEIFKIIDNEPSIDSFSTKGHKPDSIMGNLEF 393
Query: 1183 KDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLID 1362
K+V+F YPSR ++ +LKG++L++K+G +ALVG+SGCGKST V LLQR YDP +G V ID
Sbjct: 394 KNVYFNYPSRSEVKILKGLNLKVKSGQTVALVGNSGCGKSTTVQLLQRLYDPIEGEVSID 453
Query: 1363 GVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIK 1542
G D+R +NV LRE IG+VSQEPVLF TI ENI+ G E+ T D++ +A K ANA DFI
Sbjct: 454 GQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIM 513
Query: 1543 RLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALD 1722
+LP + T VGE+G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E VQ ALD
Sbjct: 514 KLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALD 573
Query: 1723 QAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXX 1902
+A+ GRTTI++AHRLST+RN D I F G IVE G+HEELM ++GI++ +
Sbjct: 574 KAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHEELMKEKGIYFKLV-MTQTRGN 632
Query: 1903 XXEAGKDIEDTISESAHSHLXXXXXXX--XXXXXXXXIHQ---------LAEEVEECKAP 2049
E G + ++ S++ S L IH+ E+V+E P
Sbjct: 633 EIEPGNNAYESQSDTGASELTSEESKSPLIRRSIRRSIHRRQDQERRLSSKEDVDE-DVP 691
Query: 2050 PTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQ--MQANVY 2223
S ++I K N + + + PVFA+V+++I V+S D Q N
Sbjct: 692 MVSFWQILKLNISEWPYLVVGVLCAVINGCIQPVFAIVFSKIVGVFSRDDDHETKQRNCN 751
Query: 2224 FWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGK 2403
+ +F++MG+ FV +F G+ GE LT +LR+ FK++LRQDI+++DD ++ TG
Sbjct: 752 LFSLLFLVMGMISFVTYFFQGFTFGKAGEILTKRLRYMVFKSMLRQDISWFDDHKNTTGS 811
Query: 2404 LCTRFATDAPNVRYVF-TRLPVVLASIVTICGA--LGIGFYYGWQXXXXXXXXXXXXXMG 2574
L TR A+DA NV+ +RL VV ++ + L + YGWQ +G
Sbjct: 812 LTTRLASDASNVKGAMGSRLAVVTQNVANLGTGIILSLVLVYGWQLTLLLVVIIPLIVLG 871
Query: 2575 GYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTN 2754
G EM++ G+ ++D + LE +GK+A++A+E+ RTV SL R+++F Y + L+ P+
Sbjct: 872 GIIEMKLLSGQALKDKKELEISGKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNA 931
Query: 2755 LKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNT 2934
LK AH +G FAF+Q++I+F YAA F G+ V ++ M +V VF A+ F GNT
Sbjct: 932 LKKAHVFGITFAFTQAMIYFSYAACFRFGAYLVARELMTFENVMLVFSAVVFGAMAAGNT 991
Query: 2935 TSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKP--ITGNISIRNVFFNYPTRKDT 3108
+SF PD KA+++AS + +IE IDS S G+ KP + GN+ V FNYPTR +
Sbjct: 992 SSFAPDYAKAKVSASHIIGIIEKIPEIDSYSTEGL-KPNWLEGNVKFNGVKFNYPTRPNI 1050
Query: 3109 KVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLR 3288
VLQG + ++K G+T+ LVG SGCGKST++ LLERFYN G + +DG I+ LN+ +R
Sbjct: 1051 PVLQGLSFEVKKGQTLRLVGSSGCGKSTVVQLLERFYNPMAGTVFLDGKEIKQLNVQCVR 1110
Query: 3289 EQVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVG 3465
+ IVSQEP LFDC+I ENI YG N R V+++EIV AA+ ANIH FI LP+ Y+T VG
Sbjct: 1111 -ALGIVSQEPILFDCSIAENIAYGDNSRVVSHEEIVRAAREANIHQFIDSLPEKYNTRVG 1169
Query: 3466 EKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVI 3645
+KGTQLSGGQKQRIAIARALVR P +LLLDEATSALDTESEK+VQEALD A++GRTC+VI
Sbjct: 1170 DKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCVVI 1229
Query: 3646 AHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIY 3756
AHRLSTIQN+D+I ++ G++ E GTH +L+ + IY
Sbjct: 1230 AHRLSTIQNADLIVVIQNGQVKEHGTHQQLLAQKGIY 1266
Score = 407 bits (1045), Expect = e-111
Identities = 232/583 (39%), Positives = 348/583 (58%), Gaps = 7/583 (1%)
Frame = +1
Query: 148 LITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSE 327
L+ G + AVI+G P+ AIV + VF R + D N N
Sbjct: 709 LVVGVLCAVINGCIQPVFAIVFSKIVGVFSR--DDDHETKQRNCN--------------- 751
Query: 328 VVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD--KQQT 501
+ + +LV+G++ F T + Q F E L +LR K++LRQ I WFD K T
Sbjct: 752 --LFSLLFLVMGMISFVTYFFQGFTFGKAGEILTKRLRYMVFKSMLRQDISWFDDHKNTT 809
Query: 502 GNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGY--GVGFFYSWSMTLVMMGFAPLIV 675
G+LT RL D V+ +G + A++ Q A G + Y W +TL+++ PLIV
Sbjct: 810 GSLTTRLASDASNVKGAMGSRLAVVTQNVANLGTGIILSLVLVYGWQLTLLLVVIIPLIV 869
Query: 676 LSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQ 855
L G K ++ + +++ ++G IA E + RTV SL ++ + +L++ +
Sbjct: 870 LGGIIEMKLLSGQALKDKKELEISGKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYR 929
Query: 856 TGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIIND-PTFDRGLIFTVFFAVLSGSTS 1032
+ K GI F+ +Y SYA F +G+ L+ + TF+ + VF AV+ G+ +
Sbjct: 930 NALKKAHVFGITFAFTQAMIYFSYAACFRFGAYLVARELMTFEN--VMLVFSAVVFGAMA 987
Query: 1033 LGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSR 1212
G + A+ +AS ++ +I P+ID YS EG+ + ++G++ F V F YP+R
Sbjct: 988 AGNTSSFAPDYAKAKVSASHIIGIIEKIPEIDSYSTEGLKPNWLEGNVKFNGVKFNYPTR 1047
Query: 1213 KDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVH 1392
+I VL+G+S E+K G + LVGSSGCGKST+V LL+RFY+P G V +DG +++++NV
Sbjct: 1048 PNIPVLQGLSFEVKKGQTLRLVGSSGCGKSTVVQLLERFYNPMAGTVFLDGKEIKQLNVQ 1107
Query: 1393 SLREQIGIVSQEPVLFDGTIYENIKMGNEH--ATHDQVVEACKMANANDFIKRLPDGYGT 1566
+R +GIVSQEP+LFD +I ENI G+ +H+++V A + AN + FI LP+ Y T
Sbjct: 1108 CVRA-LGIVSQEPILFDCSIAENIAYGDNSRVVSHEEIVRAAREANIHQFIDSLPEKYNT 1166
Query: 1567 RVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTT 1746
RVG+KG QLSGGQKQRIAIARALV+ P ILLLDEATSALDTE+E+ VQ ALD+A+ GRT
Sbjct: 1167 RVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTC 1226
Query: 1747 IIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM 1875
+++AHRLSTI+N D I V + G + E G+H++L++++GI++ M
Sbjct: 1227 VVIAHRLSTIQNADLIVVIQNGQVKEHGTHQQLLAQKGIYFSM 1269
Score = 347 bits (890), Expect = 1e-93
Identities = 209/488 (42%), Positives = 288/488 (58%), Gaps = 3/488 (0%)
Frame = +1
Query: 2323 KLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIVTICGA 2499
K+R + F ++ Q+I ++D + G+L TR D + + +L + SI T
Sbjct: 145 KIRQKFFHAIMNQEIGWFDV--NDAGELNTRLTDDVSKINDGIGDKLGMFFQSITTFSAG 202
Query: 2500 LGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRT 2679
IGF GW+ + ++ ++ Q +AG VA + + IRT
Sbjct: 203 FIIGFISGWKLTLVILAVSPLIGLSSAMWAKVLTSFTNKELQAYAKAGAVAEEVLAAIRT 262
Query: 2680 VHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQ 2859
V + Q++ Y + L E +K A T + L++ YA AF+ G+ V
Sbjct: 263 VIAFGGQKKELERYNKNLEEAKRVGIKKAITANISIGIAYLLVYASYALAFWYGTSLVLS 322
Query: 2860 QAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGI 3039
V VFF+I IG+ I AR AA +F +I++ IDS S G
Sbjct: 323 NEYSIGQVLTVFFSILLGTFSIGHLAPNIEAFANARGAAYEIFKIIDNEPSIDSFSTKGH 382
Query: 3040 VKP--ITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLER 3213
KP I GN+ +NV+FNYP+R + K+L+G L +K+G+TVALVG+SGCGKST + LL+R
Sbjct: 383 -KPDSIMGNLEFKNVYFNYPSRSEVKILKGLNLKVKSGQTVALVGNSGCGKSTTVQLLQR 441
Query: 3214 FYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIV 3393
Y+ +G + IDG +IR +N+ LRE + +VSQEP LF TI ENI YG NVT EI
Sbjct: 442 LYDPIEGEVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYG-RENVTMDEIE 500
Query: 3394 EAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSAL 3573
+A K AN ++FI+ LP +DT VGE+G QLSGGQKQRIAIARALVR+P +LLLDEATSAL
Sbjct: 501 KAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSAL 560
Query: 3574 DTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEI 3753
DTESE +VQ ALD A++GRT +VIAHRLST++N+DVIA G IVE+G H+EL+++ I
Sbjct: 561 DTESEAVVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHEELMKEKGI 620
Query: 3754 YQKFCETQ 3777
Y K TQ
Sbjct: 621 YFKLVMTQ 628
>gi|22759019|gb|AAN05645.1| multidrug resistance p-glycoprotein [Canis
familiaris]
Length = 1281
Score = 1034 bits (2673), Expect = 0.0
Identities = 553/1247 (44%), Positives = 793/1247 (63%), Gaps = 20/1247 (1%)
Frame = +1
Query: 97 LTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRA---QNSDFVVG 267
++ + +F Y+ +D L ++ GT+AA+IHGA PL+ +V G MT F A +N F V
Sbjct: 34 VSTFAMFRYSNWLDRLYMLVGTMAAIIHGAALPLMMLVFGNMTDSFANAGISRNKAFPV- 92
Query: 268 VDNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQN 447
+ N + ++ E+ Y YY +G + +Y+Q++ + A R + K+R+
Sbjct: 93 IINESITNNTQHFINHLEEEMTTYAYYYSGIGAGVLVAAYIQVSFWCLAAGRQILKIRKQ 152
Query: 448 YLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFY 627
+ AI+RQ+I WFD G L RLTDD+ ++ EG+GDK + A F G+ VGF
Sbjct: 153 FFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFHSIATFFTGFIVGFTR 212
Query: 628 SWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGH 807
W +TLV++ +P++ LS A +K +++ T E YA AGA+AEE ++IRTV + G
Sbjct: 213 GWKLTLVILAISPVLGLSAAIWAKILSSFTDKELLAYAKAGAVAEEVLAAIRTVIAFGGQ 272
Query: 808 KRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRG 987
K+EL+R+ LE + GI K I +G + L +Y+SYALAFWYG++L+++ + G
Sbjct: 273 KKELERYNKNLEEAKGIGIKKAITANISIGAAFLLIYASYALAFWYGTSLVLSSE-YSIG 331
Query: 988 LIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMK 1167
+ TVFF+VL G+ S+G A P + +F ARGAA + ++I++ P ID YS G DN+K
Sbjct: 332 QVLTVFFSVLIGAFSIGQASPSIEAFANARGAAYEIFKIIDNKPSIDSYSKSGHKPDNIK 391
Query: 1168 GDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKG 1347
G++ FK+VHF YPSRK++ +LKG++L++++G +ALVG+SGCGKST V L+QR YDPT G
Sbjct: 392 GNLEFKNVHFSYPSRKEVKILKGLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTDG 451
Query: 1348 RVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANA 1527
V IDG D+R +NV LRE G+VSQEPVLF TI ENI+ G E+ T D++ +A K ANA
Sbjct: 452 MVCIDGQDIRTINVRHLREITGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANA 511
Query: 1528 NDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREV 1707
DFI +LP+ + T VGE+G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E V
Sbjct: 512 YDFIMKLPNKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVV 571
Query: 1708 QGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXX 1887
Q ALD+A+ GRTTI++AHRLST+RN D I F G IVE G+H+ELM ++GI++ +
Sbjct: 572 QVALDKARKGRTTIVIAHRLSTVRNADVIAGFDDGVIVEKGNHDELMKEKGIYFKLVTMQ 631
Query: 1888 X---------XXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLA--EEVE 2034
+E + +S S + +L E++
Sbjct: 632 TRGNEIELENATGESKSESDALEMSPKDSGSSLIKRRSTRRSIHAPQGQDRKLGTKEDLN 691
Query: 2035 ECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQ--M 2208
E PP S ++I K N + + + P F+++++ I +++ D
Sbjct: 692 E-NVPPVSFWRILKLNSTEWPYFVVGIFCAIINGGLQPAFSIIFSRIIGIFTRDEDPETK 750
Query: 2209 QANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLR 2388
+ N + +F+++GI F+ FF G+ GE LT +LR+ F+++LRQD++++DD +
Sbjct: 751 RQNSNMFSVLFLVLGIISFITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPK 810
Query: 2389 HGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXX 2565
+ TG L TR A DA V+ + +RL V+ +I + + I YGWQ
Sbjct: 811 NTTGALTTRLANDAAQVKGAIGSRLAVITQNIANLGTGIIISLIYGWQLTLLLLAIVPII 870
Query: 2566 XMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPF 2745
+ G EM+M G+ ++D + LE AGK+A++A+E+ RTV SL R+++F + Y + L+ P+
Sbjct: 871 AIAGVVEMKMLSGQALKDKKELEGAGKIATEAIENFRTVVSLTREQKFEYMYAQSLQVPY 930
Query: 2746 NTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMI 2925
+L+ AH +G F+ +Q++++F YA F G+ V + M DV VF AI F +
Sbjct: 931 RNSLRKAHIFGVSFSITQAMMYFSYAGCFRFGAYLVANEFMNFQDVLLVFSAIVFGAMAV 990
Query: 2926 GNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPIT--GNISIRNVFFNYPTR 3099
G +SF PD KA+++A+ + +IE IDS S G+ KP T GN++ V FNYPTR
Sbjct: 991 GQVSSFAPDYAKAKVSAAHVIMIIEKSPLIDSYSPHGL-KPNTLEGNVTFNEVVFNYPTR 1049
Query: 3100 KDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNIS 3279
D VLQG +L++K G+T+ALVG SGCGKST++ LLERFY+ G ++IDG I++LN+
Sbjct: 1050 PDIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGSVLIDGKEIKHLNVQ 1109
Query: 3280 SLREQVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDT 3456
LR + IVSQEP LFDC+I ENI YG N R V+++EI++AAK ANIH+FI LP+ Y+T
Sbjct: 1110 WLRAHLGIVSQEPILFDCSIAENIAYGDNSRVVSHEEIMQAAKEANIHHFIETLPEKYNT 1169
Query: 3457 HVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTC 3636
VG+KGTQLSGGQKQRIAIARALVR P +LLLDEATSALDTESEK+VQEALD A++GRTC
Sbjct: 1170 RVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTC 1229
Query: 3637 LVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
+VIAHRLSTIQN+D+I + GK+ E GTH +L+ + IY Q
Sbjct: 1230 IVIAHRLSTIQNADLIVVFQNGKVKEHGTHQQLLAQKGIYFSMVSVQ 1276
>gi|25453402|ref|NP_596892.1| ATP-binding cassette, sub-family B
(MDR/TAP), member 1A; multiple drug resistant 1a [Rattus
norvegicus]
gi|34853968|ref|XP_346684.1| hypothetical protein XP_346683 [Rattus
norvegicus]
gi|7739773|gb|AAF69007.1| multidrug resistance protein 1a [Rattus
norvegicus]
Length = 1272
Score = 1033 bits (2671), Expect = 0.0
Identities = 557/1239 (44%), Positives = 785/1239 (62%), Gaps = 17/1239 (1%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F Y +D ++ GT+AA+IHG PL+ +V G MT F N+ + N
Sbjct: 38 MFRYAGWLDRFYMLLGTLAAIIHGIALPLMMLVFGDMTDSFANVGNNR---SMSFYNATD 94
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
+ + E+ Y YY +G + +Y+Q++ + A R +HK+RQ + AI+ Q
Sbjct: 95 IYA----KLEDEMTTYAYYYTGIGAGVLIVAYIQVSLWCLAAGRQIHKIRQKFFHAIMNQ 150
Query: 472 QIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVM 651
+I WFD G L RLTDD+ ++ EG+GDK + Q A F G+ +GF W +TLV+
Sbjct: 151 EIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQAMATFFGGFIIGFTRGWKLTLVI 210
Query: 652 MGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFY 831
+ +P++ LS +K +++ T E + YA AGA+AEE ++IRTV + G K+EL+R+
Sbjct: 211 LAISPVLGLSAGIWAKILSSFTDKELQAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYN 270
Query: 832 NALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFA 1011
N LE ++ GI K I +G + L +Y+SYALAFWYG++L+I+ + G + TVFF+
Sbjct: 271 NNLEEAKRLGIKKAITANISMGAAFLLIYASYALAFWYGTSLVISKE-YTIGQVLTVFFS 329
Query: 1012 VLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDV 1191
VL G+ S+G A P++ +F ARGAA V +I++ P ID +S G DN++G++ FK++
Sbjct: 330 VLIGAFSVGQASPNIEAFANARGAAYEVFSIIDNKPSIDSFSKSGHKPDNIQGNLEFKNI 389
Query: 1192 HFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVD 1371
HF YPSRKD+ +LKG++L++K+G +ALVG+SGCGKST V LLQR YDP +G V IDG D
Sbjct: 390 HFSYPSRKDVQILKGLNLKVKSGQTVALVGNSGCGKSTTVQLLQRLYDPIEGEVSIDGQD 449
Query: 1372 LREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLP 1551
+R +NV LRE IG+VSQEPVLF TI ENI+ G E+ T D++ +A K ANA DFI +LP
Sbjct: 450 IRTINVRYLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLP 509
Query: 1552 DGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQ 1731
+ T VGE+G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E VQ ALD+A+
Sbjct: 510 HKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKAR 569
Query: 1732 AGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXX---XXX 1902
GRTTI++AHRLST+RN D I F G IVE G+H+ELM ++GI++ +
Sbjct: 570 EGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHDELMREKGIYFKLVMTQTAGNEIEL 629
Query: 1903 XXEA--GKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKA-----PPTSM 2061
EA KD D + S+ H E+ +A PP S
Sbjct: 630 GNEACESKDGIDNVDMSSKDSGSSLIRRRSTRKSIRGPHDQDGELSTKEALDDDVPPASF 689
Query: 2062 FKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYS---LPADQMQANVYFWC 2232
++I K N + + + P F+++++++ V++ P Q Q N +
Sbjct: 690 WRILKLNSTEWPYFVVGVFCAIINGGLQPAFSIIFSKVVGVFTKNDTPEIQRQ-NSNLFS 748
Query: 2233 GMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCT 2412
+F+++GI F+ FF G+ GE LT +LR+ FK++LRQDI+++DD ++ TG L T
Sbjct: 749 LLFLILGIISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDISWFDDPKNTTGALTT 808
Query: 2413 RFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEM 2589
R A DA V+ +RL V+ +I + + I YGWQ + G EM
Sbjct: 809 RLANDAAQVKGATGSRLAVITQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAIAGVVEM 868
Query: 2590 QMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAH 2769
+M G+ ++D + LE +GK+A++A+E+ RTV SL R+++F Y + L+ P+ LK AH
Sbjct: 869 KMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNALKKAH 928
Query: 2770 TYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIP 2949
+G F+F+Q++++F YAA F G+ V ++ M +V VF AI F +G +SF P
Sbjct: 929 VFGITFSFTQAMMYFSYAACFRFGAYLVARELMTFENVLLVFSAIVFGAMAVGQVSSFAP 988
Query: 2950 DVVKARLAASLLFYLIEHPTPIDSLSDSGIVKP--ITGNISIRNVFFNYPTRKDTKVLQG 3123
D KA+++AS + +IE IDS S G+ KP + GN+ V FNYPTR + VLQG
Sbjct: 989 DYAKAKVSASHIIRIIEKIPEIDSYSTEGL-KPNMLEGNVKFNGVMFNYPTRPNIPVLQG 1047
Query: 3124 FTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCI 3303
+L++K G+T+ALVG SGCGKST++ LLERFY+ G + +DG I+ LN+ LR + I
Sbjct: 1048 LSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGTVFLDGKEIKQLNVQWLRAHLGI 1107
Query: 3304 VSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQ 3480
VSQEP LFDC+I ENI YG N R V+++EIV+AAK ANIH FI LP+ Y+T VG+KGTQ
Sbjct: 1108 VSQEPILFDCSIAENIAYGDNSRVVSHEEIVKAAKEANIHQFIDSLPEKYNTRVGDKGTQ 1167
Query: 3481 LSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLS 3660
LSGGQKQRIAIARALVR P +LLLDEATSALDTESEK+VQEALD A++GRTC+VIAHRLS
Sbjct: 1168 LSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLS 1227
Query: 3661 TIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
TIQN+D+I ++ G++ E GTH +L+ + IY Q
Sbjct: 1228 TIQNADLIVVIQNGQVKEHGTHQQLLAQKGIYFSMVSVQ 1266
>gi|2852441|gb|AAC02113.1| multidrug resistance p-glycoprotein [Canis
familiaris]
Length = 1280
Score = 1031 bits (2667), Expect = 0.0
Identities = 552/1247 (44%), Positives = 794/1247 (63%), Gaps = 20/1247 (1%)
Frame = +1
Query: 97 LTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRA---QNSDFVVG 267
++ + +F Y+ +D L ++ GT+AA+IHGA PL+ +V G MT F A +N F V
Sbjct: 33 VSTFAMFRYSNWLDRLYMLVGTMAAIIHGAALPLMMLVFGNMTDSFANAGISRNKTFPV- 91
Query: 268 VDNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQN 447
+ N + ++ E+ Y YY +G + +Y+Q++ + A R + K+R+
Sbjct: 92 IINESITNNTQHFINHLEEEMTTYAYYYSGIGAGVLVAAYIQVSFWCLAAGRQILKIRKQ 151
Query: 448 YLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFY 627
+ AI+RQ+I WFD G L RLTDD+ ++ EG+GDK + Q A F G+ VGF
Sbjct: 152 FFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKVGMFFQSIATFFTGFIVGFTP 211
Query: 628 SWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGH 807
W +TLV++ +P++ LS A +K +++ T E YA AGA+AEE ++IRTV + G
Sbjct: 212 GWKLTLVILAISPVLGLSAAIWAKILSSFTDKELLAYAKAGAVAEEVLAAIRTVIAFGGQ 271
Query: 808 KRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRG 987
K+EL+R+ LE ++ GI K I +G + L +Y+SYALAFWYG++L+++ + G
Sbjct: 272 KKELERYNKNLEEAKRIGIKKAITANISIGAAFLLIYASYALAFWYGTSLVLSSE-YTIG 330
Query: 988 LIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMK 1167
+ TVFF+VL G+ S+G A P + +F ARGAA + ++I++ P ID YS G DN+K
Sbjct: 331 QVLTVFFSVLIGAFSIGQASPSIEAFANARGAAYEIFKIIDNKPSIDSYSKSGHKPDNIK 390
Query: 1168 GDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKG 1347
G++ FK+VHF YPSRK++ +LKG++L++++G +ALVG+SGCGKST V L+QR YDPT G
Sbjct: 391 GNLEFKNVHFSYPSRKEVKILKGLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTDG 450
Query: 1348 RVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANA 1527
V IDG D+R +NV LRE G+VSQEPVLF TI ENI+ G E+ T D++ +A K ANA
Sbjct: 451 MVCIDGQDIRTINVRHLREITGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANA 510
Query: 1528 NDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREV 1707
DFI +LP+ + T VGE+G +LSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E V
Sbjct: 511 YDFIMKLPNKFDTLVGERGARLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVV 570
Query: 1708 QGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXX 1887
Q ALD+A+ GRTTI++AHRLST+RN D I F G IVE G+H+ELM ++GI++ +
Sbjct: 571 QVALDKARKGRTTIVIAHRLSTVRNADVIAGFDDGVIVEKGNHDELMKEKGIYFKLVTMQ 630
Query: 1888 X---------XXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLA--EEVE 2034
+E + +S S + +L E++
Sbjct: 631 TRGNEIELENATGESKSESDALEMSPKDSGSSLIKRRSTRRSIHAPQGQDRKLGTKEDLN 690
Query: 2035 ECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQ--M 2208
E P S ++I K N + + + P F+++++ I +++ D
Sbjct: 691 E-NVPSVSFWRILKLNSTEWPYFVVGIFCAIINGGLQPAFSIIFSRIIGIFTRDEDPETK 749
Query: 2209 QANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLR 2388
+ N + +F+++GI F+ FF G+ GE LT +LR+ F+++LRQD++++DD +
Sbjct: 750 RQNSNMFSVLFLVLGIISFITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPK 809
Query: 2389 HGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXX 2565
+ TG L TR A DA V+ + +RL V+ +I + + I YGWQ
Sbjct: 810 NTTGALTTRLANDAAQVKGAIGSRLAVITQNIANLGTGIIISLIYGWQLTLLLLAIVPII 869
Query: 2566 XMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPF 2745
+ G EM+M G+ ++D + LE AGK+A++A+E+ RTV SL R+++F + Y + L+ P+
Sbjct: 870 AIAGVVEMKMLSGQALKDKKELEGAGKIATEAIENFRTVVSLTREQKFEYMYAQSLQVPY 929
Query: 2746 NTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMI 2925
+L+ AH +G F+ +Q++++F YA F G+ V + M DV VF AI F +
Sbjct: 930 RNSLRKAHIFGVSFSITQAMMYFSYAGCFRFGAYLVANEFMNFQDVLLVFSAIVFGAMAV 989
Query: 2926 GNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPIT--GNISIRNVFFNYPTR 3099
G +SF PD KA+++A+ + +IE IDS S G+ KP T GN++ V FNYPTR
Sbjct: 990 GQVSSFAPDYAKAKVSAAHVIMIIEKSPLIDSYSPHGL-KPNTLEGNVTFNEVVFNYPTR 1048
Query: 3100 KDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNIS 3279
D VLQG +L++K G+T+ALVG SGCGKST++ LLERFY+ G ++IDG I++LN+
Sbjct: 1049 PDIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGSVLIDGKEIKHLNVQ 1108
Query: 3280 SLREQVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDT 3456
LR + IVSQEP LFDC+I ENI YG N R V+++EI++AAK ANIH+FI LP+ Y+T
Sbjct: 1109 WLRAHLGIVSQEPILFDCSIAENIAYGDNSRVVSHEEIMQAAKEANIHHFIETLPEKYNT 1168
Query: 3457 HVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTC 3636
VG+KGTQLSGGQKQRIAIARALVR P +LLLDEATSALDTESEK+VQEALD A++GRTC
Sbjct: 1169 RVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTC 1228
Query: 3637 LVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
+VIAHRLSTIQN+D+I + GK+ E GTH +L+ + IY Q
Sbjct: 1229 IVIAHRLSTIQNADLIVVFQNGKVKEHGTHQQLLAQKGIYFSMISVQ 1275
>gi|46394986|gb|AAS91649.1| multidrug resistance protein 1a;
P-glycoprotein [Rattus norvegicus]
Length = 1272
Score = 1030 bits (2664), Expect = 0.0
Identities = 557/1239 (44%), Positives = 784/1239 (62%), Gaps = 17/1239 (1%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F Y +D ++ GT+AA+IHG PL+ +V G MT F N+ + N
Sbjct: 38 MFRYAGWLDRFYMLLGTLAAIIHGIALPLMMLVFGDMTDSFANVGNNR---SMSFYNATD 94
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
+ + E+ Y YY +G + +Y+Q++ + A R +HK+RQ + AI+ Q
Sbjct: 95 IYA----KLKDEMTTYAYYYTGIGAGVLIVAYIQVSLWCLAAGRQIHKIRQKFFHAIMNQ 150
Query: 472 QIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVM 651
+I WFD G L RLTDD+ ++ EG+GDK + Q A F G+ +GF W +TLV+
Sbjct: 151 EIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQAMATFFGGFIIGFTRGWKLTLVI 210
Query: 652 MGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFY 831
+ +P++ LS +K +++ T E + YA AGA+AEE ++IRTV + G K+EL+R+
Sbjct: 211 LAISPVLGLSAGIWAKILSSFTDKELQAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYN 270
Query: 832 NALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFA 1011
N LE ++ GI K I +G + L +Y+SYALAFWYG++L+I+ + G + TVFF+
Sbjct: 271 NNLEEAKRLGIKKAITANISMGAAFLLIYASYALAFWYGTSLVISKE-YTIGQVLTVFFS 329
Query: 1012 VLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDV 1191
VL G+ S+G A P++ +F ARGAA V +I++ P ID +S G DN++G++ FK++
Sbjct: 330 VLIGAFSVGQASPNIEAFANARGAAYEVFSIIDNKPSIDSFSKSGHKPDNIQGNLEFKNI 389
Query: 1192 HFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVD 1371
HF YPSRKD+ +LKG++L++K+G +ALVG+SGCGKST V LLQR YDP +G V IDG D
Sbjct: 390 HFSYPSRKDVQILKGLNLKVKSGQTVALVGNSGCGKSTTVQLLQRLYDPIEGEVSIDGQD 449
Query: 1372 LREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLP 1551
+R +NV LRE IG+VSQEPVLF TI ENI+ G E+ T D++ +A K ANA DFI +LP
Sbjct: 450 IRTINVRYLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLP 509
Query: 1552 DGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQ 1731
+ T VGE+G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E VQ ALD+A+
Sbjct: 510 HKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKAR 569
Query: 1732 AGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXX---XXX 1902
GRTTI++AHRLST+RN D I F G IVE G+H+ELM ++GI++ +
Sbjct: 570 EGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHDELMREKGIYFKLVMTQTAGNEIEL 629
Query: 1903 XXEA--GKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKA-----PPTSM 2061
EA KD D + S+ H E+ +A PP S
Sbjct: 630 GNEACESKDGIDNVDMSSKDSGSSLIRRRSTRKSIRGPHDQDGELSTKEALDDDVPPASF 689
Query: 2062 FKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYS---LPADQMQANVYFWC 2232
++I K N + + + P F+++++++ V++ P Q Q N +
Sbjct: 690 WRILKLNSTEWPYFVVGVFCAIINGGLQPAFSIIFSKVVGVFTKNDTPEIQRQ-NSNLFS 748
Query: 2233 GMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCT 2412
+F+++GI F+ FF G+ GE LT +LR+ FK++LRQDI+++DD ++ TG L T
Sbjct: 749 LLFLILGIISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDISWFDDPKNTTGALTT 808
Query: 2413 RFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEM 2589
R A DA V+ +RL V+ +I + + I YGWQ + G EM
Sbjct: 809 RLANDAAQVKGATGSRLAVITQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAIAGVVEM 868
Query: 2590 QMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAH 2769
+M G+ ++D + LE +GK+A++A+E+ RTV SL R+++F Y + L+ P+ LK AH
Sbjct: 869 KMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNALKKAH 928
Query: 2770 TYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIP 2949
+G F+F+Q++++F YAA F G+ V ++ M +V VF AI F +G +SF P
Sbjct: 929 VFGITFSFTQAMMYFSYAACFRFGAYLVARELMTFENVLLVFSAIVFGAMAVGQVSSFAP 988
Query: 2950 DVVKARLAASLLFYLIEHPTPIDSLSDSGIVKP--ITGNISIRNVFFNYPTRKDTKVLQG 3123
D KA+++AS + +IE IDS S G+ KP + GN+ V FNYPTR + VLQG
Sbjct: 989 DYAKAKVSASHIIRIIEKIPEIDSYSTEGL-KPNMLEGNVKFNGVMFNYPTRPNIPVLQG 1047
Query: 3124 FTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCI 3303
+L+ K G+T+ALVG SGCGKST++ LLERFY+ G + +DG I+ LN+ LR + I
Sbjct: 1048 LSLEGKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGTVFLDGKEIKQLNVQWLRAHLGI 1107
Query: 3304 VSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQ 3480
VSQEP LFDC+I ENI YG N R V+++EIV+AAK ANIH FI LP+ Y+T VG+KGTQ
Sbjct: 1108 VSQEPILFDCSIAENIAYGDNSRVVSHEEIVKAAKEANIHQFIDSLPEKYNTRVGDKGTQ 1167
Query: 3481 LSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLS 3660
LSGGQKQRIAIARALVR P +LLLDEATSALDTESEK+VQEALD A++GRTC+VIAHRLS
Sbjct: 1168 LSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLS 1227
Query: 3661 TIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
TIQN+D+I ++ G++ E GTH +L+ + IY Q
Sbjct: 1228 TIQNADLIVVIQNGQVKEHGTHQQLLAQKGIYFSMVSVQ 1266
>gi|6679297|ref|NP_032856.1| ATP-binding cassette, sub-family B
(MDR/TAP), member 4; P glycoprotein 2 [Mus musculus]
gi|126929|sp|P21440|MDR2_MOUSE Multidrug resistance protein 2
(P-glycoprotein 2)
gi|72476|pir||DVMS2 multidrug resistance protein 2 - mouse
gi|387428|gb|AAA39516.1| multidrug resistance protein
Length = 1276
Score = 1025 bits (2650), Expect = 0.0
Identities = 571/1237 (46%), Positives = 769/1237 (62%), Gaps = 22/1237 (1%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F Y+ D L + GT+ A+ HG+G PL+ IV G MT F VDN
Sbjct: 42 LFRYSDWQDKLFMFLGTLMAIAHGSGLPLMMIVFGEMTDKF-----------VDNTGNFS 90
Query: 292 L-VPISLDEFN------SEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNY 450
L V SL N E+ +Y YY LG + +Y+Q++ + A R + K+RQ +
Sbjct: 91 LPVNFSLSMLNPGRILEEEMTRYAYYYSGLGGGVLVAAYIQVSFWTLAAGRQIKKIRQKF 150
Query: 451 LKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYS 630
AILRQ++ WFD + T L RLTDD+ ++ EG+GDK + Q A F AG+ VGF
Sbjct: 151 FHAILRQEMGWFDIKGTTELNTRLTDDVSKISEGIGDKVGMFFQAIATFFAGFIVGFIRG 210
Query: 631 WSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHK 810
W +TLV+M +P++ LS A +K ++T + E YA AGA+AEE +IRTV + G
Sbjct: 211 WKLTLVIMAISPILGLSTAVWAKILSTFSDKELAAYAKAGAVAEEAPGAIRTVIAFGGQN 270
Query: 811 RELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGL 990
+EL+R+ LE ++ GI K I +G + L +Y+SYALAFWYGSTL+I+ + G
Sbjct: 271 KELERYQKHLENAKKIGIKKAISANISMGIAFLLIYASYALAFWYGSTLVISKE-YTIGN 329
Query: 991 IFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKG 1170
TVFF++L G+ S+G A P + +F ARGAA + +I+++PKID +S G DN+KG
Sbjct: 330 AMTVFFSILIGAFSVGQAAPCIDAFANARGAAYVIFDIIDNNPKIDSFSERGHKPDNIKG 389
Query: 1171 DISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGR 1350
++ F DVHF YPSR +I +LKG++L++K+G +ALVG+SGCGKST V LLQR YDPT+G+
Sbjct: 390 NLEFSDVHFSYPSRANIKILKGLNLKVKSGQTVALVGNSGCGKSTTVQLLQRLYDPTEGK 449
Query: 1351 VLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAN 1530
+ IDG D+R NV LRE IG+VSQEPVLF TI ENI+ G + T D++ +A K ANA
Sbjct: 450 ISIDGQDIRNFNVRCLREIIGVVSQEPVLFSTTIAENIRYGRGNVTMDEIEKAVKEANAY 509
Query: 1531 DFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQ 1710
DFI +LP + T VG++G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E EVQ
Sbjct: 510 DFIMKLPQKFDTLVGDRGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQ 569
Query: 1711 GALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM----T 1878
ALD+A+ GRTTI++AHRLSTIRN D I F+ G IVE GSH ELM K+GI++ + T
Sbjct: 570 AALDKAREGRTTIVIAHRLSTIRNADVIAGFEDGVIVEQGSHSELMKKEGIYFRLVNMQT 629
Query: 1879 XXXXXXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQ--LAEEVEECKA-- 2046
E E + A + HQ L EE E A
Sbjct: 630 AGSQILSEEFEVELSDEKAAGDVAPNGWKARIFRNSTKKSLKSPHQNRLDEETNELDANV 689
Query: 2047 PPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANVYF 2226
PP S K+ K N + + ++ P F+++ +E+ ++ D ++
Sbjct: 690 PPVSFLKVLKLNKTEWPYFVVGTVCAIANGALQPAFSIILSEMIAIFGPGDDAVKQQK-- 747
Query: 2227 WCGMFVL----MGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHG 2394
C MF L +G+ F FF G+ GE LT +LR AFK +LRQD++++DD ++
Sbjct: 748 -CNMFSLVFLGLGVLSFFTFFLQGFTFGKAGEILTTRLRSMAFKAMLRQDMSWFDDHKNS 806
Query: 2395 TGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXM 2571
TG L TR ATDA V+ T+L ++ + + + I F YGWQ +
Sbjct: 807 TGALSTRLATDAAQVQGATGTKLALIAQNTANLGTGIIISFIYGWQLTLLLLSVVPFIAV 866
Query: 2572 GGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNT 2751
G EM+M G RD + +E AGK+A++A+E+IRTV SL ++ +F Y E L P+
Sbjct: 867 AGIVEMKMLAGNAKRDKKEMEAAGKIATEAIENIRTVVSLTQERKFESMYVEKLHGPYRN 926
Query: 2752 NLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGN 2931
+++ AH YG F+ SQ+ ++F YA F GS + M+ DV VF AI +G+
Sbjct: 927 SVRKAHIYGITFSISQAFMYFSYAGCFRFGSYLIVNGHMRFKDVILVFSAIVLGAVALGH 986
Query: 2932 TTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGI-VKPITGNISIRNVFFNYPTRKDT 3108
+SF PD KA+L+A+ LF L E IDS S G+ G+++ V FNYPTR +
Sbjct: 987 ASSFAPDYAKAKLSAAYLFSLFERQPLIDSYSGEGLWPDKFEGSVTFNEVVFNYPTRANV 1046
Query: 3109 KVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLR 3288
VLQG +L++K G+T+ALVG SGCGKST++ LLERFY+ G +++DG + LN+ LR
Sbjct: 1047 PVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSVLLDGQEAKKLNVQWLR 1106
Query: 3289 EQVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVG 3465
Q+ IVSQEP LFDC+I ENI YG N R V + EIV AAK ANIH FI LP Y+T VG
Sbjct: 1107 AQLGIVSQEPILFDCSIAENIAYGDNSRVVPHDEIVRAAKEANIHPFIETLPQKYNTRVG 1166
Query: 3466 EKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVI 3645
+KGTQLSGGQKQRIAIARAL+R P VLLLDEATSALDTESEK+VQEALD A++GRTC+VI
Sbjct: 1167 DKGTQLSGGQKQRIAIARALIRQPRVLLLDEATSALDTESEKVVQEALDKAREGRTCIVI 1226
Query: 3646 AHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIY 3756
AHRLSTIQN+D+I ++ GK+ E GTH +L+ + IY
Sbjct: 1227 AHRLSTIQNADLIVVIENGKVKEHGTHQQLLAQKGIY 1263
Score = 429 bits (1102), Expect = e-118
Identities = 246/579 (42%), Positives = 344/579 (58%), Gaps = 4/579 (0%)
Frame = +1
Query: 151 ITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEV 330
+ GTV A+ +GA P +I+L M +F D V N LV
Sbjct: 709 VVGTVCAIANGALQPAFSIILSEMIAIF---GPGDDAVKQQKCNMFSLV----------- 754
Query: 331 VKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD--KQQTG 504
+L LGVL FFT ++Q F E L +LR KA+LRQ + WFD K TG
Sbjct: 755 ------FLGLGVLSFFTFFLQGFTFGKAGEILTTRLRSMAFKAMLRQDMSWFDDHKNSTG 808
Query: 505 NLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSG 684
L+ RL D +V+ G K AL+ Q A G + F Y W +TL+++ P I ++G
Sbjct: 809 ALSTRLATDAAQVQGATGTKLALIAQNTANLGTGIIISFIYGWQLTLLLLSVVPFIAVAG 868
Query: 685 AKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGI 864
K +A + +++ AG IA E +IRTV SL ++ + L + +
Sbjct: 869 IVEMKMLAGNAKRDKKEMEAAGKIATEAIENIRTVVSLTQERKFESMYVEKLHGPYRNSV 928
Query: 865 VKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGA 1044
K GI S MY SYA F +GS LI+N + +I VF A++ G+ +LG A
Sbjct: 929 RKAHIYGITFSISQAFMYFSYAGCFRFGSYLIVNGHMRFKDVIL-VFSAIVLGAVALGHA 987
Query: 1045 LPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIH 1224
+ A+ +A+ + + P ID YS EG+ D +G ++F +V F YP+R ++
Sbjct: 988 SSFAPDYAKAKLSAAYLFSLFERQPLIDSYSGEGLWPDKFEGSVTFNEVVFNYPTRANVP 1047
Query: 1225 VLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLRE 1404
VL+G+SLE+K G +ALVGSSGCGKST+V LL+RFYDP G VL+DG + +++NV LR
Sbjct: 1048 VLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSVLLDGQEAKKLNVQWLRA 1107
Query: 1405 QIGIVSQEPVLFDGTIYENIKMGNEHAT--HDQVVEACKMANANDFIKRLPDGYGTRVGE 1578
Q+GIVSQEP+LFD +I ENI G+ HD++V A K AN + FI+ LP Y TRVG+
Sbjct: 1108 QLGIVSQEPILFDCSIAENIAYGDNSRVVPHDEIVRAAKEANIHPFIETLPQKYNTRVGD 1167
Query: 1579 KGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVA 1758
KG QLSGGQKQRIAIARAL++ P++LLLDEATSALDTE+E+ VQ ALD+A+ GRT I++A
Sbjct: 1168 KGTQLSGGQKQRIAIARALIRQPRVLLLDEATSALDTESEKVVQEALDKAREGRTCIVIA 1227
Query: 1759 HRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM 1875
HRLSTI+N D I V + G + E G+H++L++++GI++ M
Sbjct: 1228 HRLSTIQNADLIVVIENGKVKEHGTHQQLLAQKGIYFSM 1266
Score = 338 bits (868), Expect = 4e-91
Identities = 215/531 (40%), Positives = 304/531 (56%), Gaps = 5/531 (0%)
Frame = +1
Query: 2200 DQMQANVYFWCGMF--VLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAF 2373
++M Y++ G+ VL+ V F+T A G + K+R + F +LRQ++ +
Sbjct: 108 EEMTRYAYYYSGLGGGVLVAAYIQVSFWTLA-----AGRQIK-KIRQKFFHAILRQEMGW 161
Query: 2374 YDDLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXX 2550
+D GT +L TR D + + ++ + +I T +GF GW+
Sbjct: 162 FDI--KGTTELNTRLTDDVSKISEGIGDKVGMFFQAIATFFAGFIVGFIRGWKLTLVIMA 219
Query: 2551 XXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEY 2730
+ ++ ++ +AG VA +A IRTV + Q + Y ++
Sbjct: 220 ISPILGLSTAVWAKILSTFSDKELAAYAKAGAVAEEAPGAIRTVIAFGGQNKELERYQKH 279
Query: 2731 LREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISF 2910
L +K A + + LI+ YA AF+ GS V + + VFF+I
Sbjct: 280 LENAKKIGIKKAISANISMGIAFLLIYASYALAFWYGSTLVISKEYTIGNAMTVFFSILI 339
Query: 2911 CGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKP--ITGNISIRNVFF 3084
+G I AR AA ++F +I++ IDS S+ G KP I GN+ +V F
Sbjct: 340 GAFSVGQAAPCIDAFANARGAAYVIFDIIDNNPKIDSFSERGH-KPDNIKGNLEFSDVHF 398
Query: 3085 NYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIR 3264
+YP+R + K+L+G L +K+G+TVALVG+SGCGKST + LL+R Y+ +G I IDG +IR
Sbjct: 399 SYPSRANIKILKGLNLKVKSGQTVALVGNSGCGKSTTVQLLQRLYDPTEGKISIDGQDIR 458
Query: 3265 NLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPD 3444
N N+ LRE + +VSQEP LF TI ENI YG NVT EI +A K AN ++FI+ LP
Sbjct: 459 NFNVRCLREIIGVVSQEPVLFSTTIAENIRYGRG-NVTMDEIEKAVKEANAYDFIMKLPQ 517
Query: 3445 GYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQ 3624
+DT VG++G QLSGGQKQRIAIARALVR+P +LLLDEATSALDTESE VQ ALD A++
Sbjct: 518 KFDTLVGDRGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALDKARE 577
Query: 3625 GRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
GRT +VIAHRLSTI+N+DVIA +G IVE+G+H EL++K IY + Q
Sbjct: 578 GRTTIVIAHRLSTIRNADVIAGFEDGVIVEQGSHSELMKKEGIYFRLVNMQ 628
>gi|4505771|ref|NP_000434.1| ATP-binding cassette, subfamily B, member
4 isoform A; P glycoprotein 3/multiple drug resistance 3;
P-glycoprotein-3/multiple drug resistance-3; multiple
drug resistance 3 [Homo sapiens]
gi|126932|sp|P21439|MDR3_HUMAN Multidrug resistance protein 3
(P-glycoprotein 3)
gi|72473|pir||DVHU3 multidrug resistance protein 3 - human
gi|307181|gb|AAA36207.1| P-glycoprotein
Length = 1279
Score = 1025 bits (2649), Expect = 0.0
Identities = 565/1241 (45%), Positives = 774/1241 (61%), Gaps = 19/1241 (1%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFL-RAQNSDFVVG--VDNVN 282
+F Y+ D L + GT+ A+ HG+G PL+ IV G MT F+ A N F V + +N
Sbjct: 45 LFRYSDWQDKLFMSLGTIMAIAHGSGLPLMMIVFGEMTDKFVDTAGNFSFPVNFSLSLLN 104
Query: 283 PEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAI 462
P ++ E+ +Y YY LG + +Y+Q++ + A R + K+RQ + AI
Sbjct: 105 PGKIL-------EEEMTRYAYYYSGLGAGVLVAAYIQVSFWTLAAGRQIRKIRQKFFHAI 157
Query: 463 LRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMT 642
LRQ+I WFD T L RLTDD+ ++ EG+GDK + Q A F AG+ VGF W +T
Sbjct: 158 LRQEIGWFDINDTTELNTRLTDDISKISEGIGDKVGMFFQAVATFFAGFIVGFIRGWKLT 217
Query: 643 LVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELD 822
LV+M +P++ LS A +K ++ + E YA AGA+AEE +IRTV + G +EL+
Sbjct: 218 LVIMAISPILGLSAAVWAKILSAFSDKELAAYAKAGAVAEEALGAIRTVIAFGGQNKELE 277
Query: 823 RFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTV 1002
R+ LE ++ GI K I +G + L +Y+SYALAFWYGSTL+I+ + G TV
Sbjct: 278 RYQKHLENAKEIGIKKAISANISMGIAFLLIYASYALAFWYGSTLVISKE-YTIGNAMTV 336
Query: 1003 FFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISF 1182
FF++L G+ S+G A P + +F ARGAA + +I+++PKID +S G D++KG++ F
Sbjct: 337 FFSILIGAFSVGQAAPCIDAFANARGAAYVIFDIIDNNPKIDSFSERGHKPDSIKGNLEF 396
Query: 1183 KDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLID 1362
DVHF YPSR ++ +LKG++L++++G +ALVGSSGCGKST V L+QR YDP +G + ID
Sbjct: 397 NDVHFSYPSRANVKILKGLNLKVQSGQTVALVGSSGCGKSTTVQLIQRLYDPDEGTINID 456
Query: 1363 GVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIK 1542
G D+R NV+ LRE IG+VSQEPVLF TI ENI G + T D++ +A K ANA +FI
Sbjct: 457 GQDIRNFNVNYLREIIGVVSQEPVLFSTTIAENICYGRGNVTMDEIKKAVKEANAYEFIM 516
Query: 1543 RLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALD 1722
+LP + T VGE+G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E EVQ ALD
Sbjct: 517 KLPQKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALD 576
Query: 1723 QAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXX 1902
+A+ GRTTI++AHRLST+RN D I F+ G IVE GSH ELM K+G+++ +
Sbjct: 577 KAREGRTTIVIAHRLSTVRNADVIAGFEDGVIVEQGSHSELMKKEGVYFKLVNMQTSGSQ 636
Query: 1903 XXEAGKDIEDTISESA------HSHLXXXXXXXXXXXXXXXIHQLAEEVE--ECKAPPTS 2058
++ D + + S L L E + E PP S
Sbjct: 637 IQSEEFELNDEKAATRMAPNGWKSRLFRHSTQKNLKNSQMCQKSLDVETDGLEANVPPVS 696
Query: 2059 MFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPAD----QMQANVYF 2226
K+ K N + + + P F+++++EI ++ P D Q + N++
Sbjct: 697 FLKVLKLNKTEWPYFVVGTVCAIANGGLQPAFSVIFSEIIAIFG-PGDDAVKQQKCNIFS 755
Query: 2227 WCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKL 2406
+F+ +GI F FF G+ GE LT +LR AFK +LRQD++++DD ++ TG L
Sbjct: 756 L--IFLFLGIISFFTFFLQGFTFGKAGEILTRRLRSMAFKAMLRQDMSWFDDHKNSTGAL 813
Query: 2407 CTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYF 2583
TR ATDA V+ TRL ++ +I + + I F YGWQ + G
Sbjct: 814 STRLATDAAQVQGATGTRLALIAQNIANLGTGIIISFIYGWQLTLLLLAVVPIIAVSGIV 873
Query: 2584 EMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKH 2763
EM++ G RD + LE AGK+A++A+E+IRTV SL ++ +F Y E L P+ +++
Sbjct: 874 EMKLLAGNAKRDKKELEAAGKIATEAIENIRTVVSLTQERKFESMYVEKLYGPYRNSVQK 933
Query: 2764 AHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSF 2943
AH YG F+ SQ+ ++F YA F G+ + M+ DV VF AI F +G+ +SF
Sbjct: 934 AHIYGITFSISQAFMYFSYAGCFRFGAYLIVNGHMRFRDVILVFSAIVFGAVALGHASSF 993
Query: 2944 IPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKP--ITGNISIRNVFFNYPTRKDTKVL 3117
PD KA+L+A+ LF L E IDS S+ G+ KP GNI+ V FNYPTR + VL
Sbjct: 994 APDYAKAKLSAAHLFMLFERQPLIDSYSEEGL-KPDKFEGNITFNEVVFNYPTRANVPVL 1052
Query: 3118 QGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQV 3297
QG +L++K G+T+ALVG SGCGKST++ LLERFY+ G +++DG + LN+ LR Q+
Sbjct: 1053 QGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGTVLLDGQEAKKLNVQWLRAQL 1112
Query: 3298 CIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKG 3474
IVSQEP LFDC+I ENI YG N R V+ EIV AAK ANIH FI LP Y+T VG+KG
Sbjct: 1113 GIVSQEPILFDCSIAENIAYGDNSRVVSQDEIVSAAKAANIHPFIETLPHKYETRVGDKG 1172
Query: 3475 TQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHR 3654
TQLSGGQKQRIAIARAL+R P +LLLDEATSALDTESEK+VQEALD A++GRTC+VIAHR
Sbjct: 1173 TQLSGGQKQRIAIARALIRQPQILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHR 1232
Query: 3655 LSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
LSTIQN+D+I + G++ E GTH +L+ + IY Q
Sbjct: 1233 LSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMVSVQ 1273
>gi|2149087|gb|AAB58489.1| multidrug resistance protein-1 [Ovis aries]
Length = 1285
Score = 1024 bits (2648), Expect = 0.0
Identities = 547/1238 (44%), Positives = 792/1238 (63%), Gaps = 18/1238 (1%)
Frame = +1
Query: 97 LTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDN 276
++ + +F Y+ +D L ++ GT+AA+IHGAG PL+ +V G MT F A N + + N
Sbjct: 38 VSTFTMFRYSNWLDRLCMVLGTLAAIIHGAGLPLMMLVFGDMTDSFAGAGNLGNIT-LSN 96
Query: 277 VNPEGLVPISL--DEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNY 450
++ + + + E+ Y YY +G + +Y+Q++ + A R VH++R+ +
Sbjct: 97 ISNTSTIDRTEYGKKLEKEMTTYAYYYSGIGAGVLIAAYIQVSFWCLAAGRQVHRIRKQF 156
Query: 451 LKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYS 630
AI++Q+I WFD G L RLT+D+ ++ EG+GDK + Q A F G+ +GF
Sbjct: 157 FHAIMQQEIGWFDVHDVGKLNTRLTNDVSKINEGIGDKIGMFFQAMATFFTGFIIGFTTG 216
Query: 631 WSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHK 810
W++TLV++ P++ LS A +K +++ T + YA AGA+AEE ++I+TV + G K
Sbjct: 217 WNLTLVILAIIPVLGLSAAIWAKILSSFTDKKLLAYAKAGAVAEEVLAAIKTVIAFGGQK 276
Query: 811 RELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGL 990
+EL+R+ LE ++ GI K I +G + L +Y+SYALAFWYG++L+++ + G
Sbjct: 277 KELERYNKNLEEAKRIGIKKAITANISMGAAFLLIYASYALAFWYGTSLVLSRE-YSIGQ 335
Query: 991 IFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKG 1170
+ TVFF+VL G+ S+G A P++ +F ARGAA V ++I++ P ID YS G DN+KG
Sbjct: 336 VLTVFFSVLIGAFSIGQASPNIEAFANARGAAYEVFKIIDNKPSIDSYSNTGHKPDNIKG 395
Query: 1171 DISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGR 1350
++ F++VHF YPSR ++ +LKG++L++ +G +ALVG+SGCGKST V L+QR YDPT+G
Sbjct: 396 NLEFRNVHFHYPSRNEVKILKGLNLKVGSGQTVALVGNSGCGKSTTVQLMQRLYDPTEGM 455
Query: 1351 VLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAN 1530
V IDG D+R +NV LRE IG+VSQEPVLF TI ENI+ G E T D++ +A K ANA
Sbjct: 456 VSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGREDVTMDEIQKAVKEANAY 515
Query: 1531 DFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQ 1710
DFI +LP+ + T VGE+G QLSGGQKQRIAIARALV+NPKILLLDEATSAL TE+E VQ
Sbjct: 516 DFIMKLPNKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALGTESEAVVQ 575
Query: 1711 GALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXX 1890
ALD+A+ GRTTI++AHRLST+RN D I G IVE GSH+ELM K+GI++ +
Sbjct: 576 AALDKARKGRTTIVIAHRLSTVRNADIIAGLDDGVIVEEGSHDELMGKRGIYFKLVTMQT 635
Query: 1891 ---------XXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLA-EEVEEC 2040
D+ + +S S + +L+ EE +
Sbjct: 636 KGNELELENTPGESLSKTDDLYMSSQDSRSSLIRRKSTRRSIRGSQSQDRKLSTEETLDE 695
Query: 2041 KAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSL--PADQMQA 2214
PP S ++I K N + + ++ P F+++++ I +++ + +
Sbjct: 696 SVPPVSFWRILKLNITEWPYFVVGVFCAIINGALQPAFSVIFSRIIGIFTRNDNDETKRQ 755
Query: 2215 NVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHG 2394
N + +F+++GI F+ FF G+ GE LT +LR+ F+++LRQD++++DD ++
Sbjct: 756 NSNLFSLLFLILGIISFITFFLQGFTFGKAGEILTRRLRYLVFRSMLRQDVSWFDDPKNT 815
Query: 2395 TGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXM 2571
TG L TR A DA V+ V +RL V+ +I + + I YGWQ +
Sbjct: 816 TGALTTRLANDAAQVKGAVGSRLAVITQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAV 875
Query: 2572 GGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNT 2751
G EM+M G+ ++D + LE AGK+A++A+E+ RTV SL R+E+F + Y + L+ P+
Sbjct: 876 AGVIEMKMLSGQALKDKKELEGAGKIATEAIENFRTVVSLTREERFEYMYAQSLQVPYRN 935
Query: 2752 NLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGN 2931
+L+ AH +G F+ +Q++++F YA F G+ V Q M+ DV VF A+ F +G
Sbjct: 936 SLRRAHVFGITFSITQAMMYFSYAGCFRFGAYLVAQGIMEFQDVLLVFSAVVFGAMAVGQ 995
Query: 2932 TTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPIT--GNISIRNVFFNYPTRKD 3105
++F PD KA+++A+ + +IE IDS S G+ KP T G+++ +V FNYPTR D
Sbjct: 996 VSTFAPDYAKAKVSAAHVINIIEKIPLIDSYSTEGL-KPSTVEGSVAFNDVVFNYPTRPD 1054
Query: 3106 TKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSL 3285
VL+G +L++K G+T+ALVG SGCGKST++ LLERFY+ G + IDG ++ LN+ L
Sbjct: 1055 VPVLRGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGTVFIDGKEVKQLNVQWL 1114
Query: 3286 REQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVE-AAKMANIHNFILGLPDGYDTHV 3462
R + IVSQEP LFDC+IGENI YG N V QE +E AAK ANIH+FI LPD Y+T V
Sbjct: 1115 RAHMGIVSQEPILFDCSIGENIAYGDNSRVVSQEEIEHAAKEANIHSFIEMLPDKYNTRV 1174
Query: 3463 GEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLV 3642
G+KGTQLSGGQKQRIAIARALVR P +LLLDEATSALDTESEK+VQEALD A++GRTC+V
Sbjct: 1175 GDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIV 1234
Query: 3643 IAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIY 3756
IAHRLSTIQN+D+I + G+I E GTH +L+ + IY
Sbjct: 1235 IAHRLSTIQNADLIVVFQNGRIKEHGTHQQLLAQKGIY 1272
Score = 417 bits (1072), Expect = e-114
Identities = 230/579 (39%), Positives = 345/579 (58%), Gaps = 4/579 (0%)
Frame = +1
Query: 151 ITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEV 330
+ G A+I+GA P +++ + +F R N + N+
Sbjct: 717 VVGVFCAIINGALQPAFSVIFSRIIGIFTRNDNDETKRQNSNL----------------- 759
Query: 331 VKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD--KQQTG 504
+ + +L+LG++ F T ++Q F E L +LR +++LRQ + WFD K TG
Sbjct: 760 --FSLLFLILGIISFITFFLQGFTFGKAGEILTRRLRYLVFRSMLRQDVSWFDDPKNTTG 817
Query: 505 NLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSG 684
LT RL +D +V+ +G + A++ Q A G + Y W +TL+++ P+I ++G
Sbjct: 818 ALTTRLANDAAQVKGAVGSRLAVITQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAVAG 877
Query: 685 AKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGI 864
K ++ + +++ AG IA E + RTV SL +R + +L+V + +
Sbjct: 878 VIEMKMLSGQALKDKKELEGAGKIATEAIENFRTVVSLTREERFEYMYAQSLQVPYRNSL 937
Query: 865 VKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGA 1044
+ GI + MY SYA F +G+ L+ + + VF AV+ G+ ++G
Sbjct: 938 RRAHVFGITFSITQAMMYFSYAGCFRFGAYLVAQG-IMEFQDVLLVFSAVVFGAMAVGQV 996
Query: 1045 LPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIH 1224
+ A+ +A+ V+ +I P ID YS EG+ ++G ++F DV F YP+R D+
Sbjct: 997 STFAPDYAKAKVSAAHVINIIEKIPLIDSYSTEGLKPSTVEGSVAFNDVVFNYPTRPDVP 1056
Query: 1225 VLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLRE 1404
VL+G+SLE+K G +ALVGSSGCGKST+V LL+RFYDP G V IDG +++++NV LR
Sbjct: 1057 VLRGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGTVFIDGKEVKQLNVQWLRA 1116
Query: 1405 QIGIVSQEPVLFDGTIYENIKMGNEH--ATHDQVVEACKMANANDFIKRLPDGYGTRVGE 1578
+GIVSQEP+LFD +I ENI G+ + +++ A K AN + FI+ LPD Y TRVG+
Sbjct: 1117 HMGIVSQEPILFDCSIGENIAYGDNSRVVSQEEIEHAAKEANIHSFIEMLPDKYNTRVGD 1176
Query: 1579 KGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVA 1758
KG QLSGGQKQRIAIARALV+ P ILLLDEATSALDTE+E+ VQ ALD+A+ GRT I++A
Sbjct: 1177 KGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIA 1236
Query: 1759 HRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM 1875
HRLSTI+N D I VF+ G I E G+H++L++++GI++ M
Sbjct: 1237 HRLSTIQNADLIVVFQNGRIKEHGTHQQLLAQKGIYFTM 1275
Score = 337 bits (863), Expect = 2e-90
Identities = 205/490 (41%), Positives = 292/490 (58%), Gaps = 5/490 (1%)
Frame = +1
Query: 2323 KLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIVTICGA 2499
++R + F +++Q+I ++D H GKL TR D + + ++ + ++ T
Sbjct: 151 RIRKQFFHAIMQQEIGWFDV--HDVGKLNTRLTNDVSKINEGIGDKIGMFFQAMATFFTG 208
Query: 2500 LGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLE--EAGKVASQAVEHI 2673
IGF GW + + + D +LL +AG VA + + I
Sbjct: 209 FIIGFTTGWNLTLVILAIIPVLGLSA--AIWAKILSSFTDKKLLAYAKAGAVAEEVLAAI 266
Query: 2674 RTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFV 2853
+TV + Q++ Y + L E +K A T + LI+ YA AF+ G+ V
Sbjct: 267 KTVIAFGGQKKELERYNKNLEEAKRIGIKKAITANISMGAAFLLIYASYALAFWYGTSLV 326
Query: 2854 NQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDS 3033
+ V VFF++ IG + I AR AA +F +I++ IDS S++
Sbjct: 327 LSREYSIGQVLTVFFSVLIGAFSIGQASPNIEAFANARGAAYEVFKIIDNKPSIDSYSNT 386
Query: 3034 GIVKP--ITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLL 3207
G KP I GN+ RNV F+YP+R + K+L+G L + +G+TVALVG+SGCGKST + L+
Sbjct: 387 GH-KPDNIKGNLEFRNVHFHYPSRNEVKILKGLNLKVGSGQTVALVGNSGCGKSTTVQLM 445
Query: 3208 ERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQE 3387
+R Y+ +GM+ IDG +IR +N+ LRE + +VSQEP LF TI ENI YG +VT E
Sbjct: 446 QRLYDPTEGMVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYG-REDVTMDE 504
Query: 3388 IVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATS 3567
I +A K AN ++FI+ LP+ +DT VGE+G QLSGGQKQRIAIARALVR+P +LLLDEATS
Sbjct: 505 IQKAVKEANAYDFIMKLPNKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATS 564
Query: 3568 ALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKS 3747
AL TESE +VQ ALD A++GRT +VIAHRLST++N+D+IA + +G IVE+G+HDEL+ K
Sbjct: 565 ALGTESEAVVQAALDKARKGRTTIVIAHRLSTVRNADIIAGLDDGVIVEEGSHDELMGKR 624
Query: 3748 EIYQKFCETQ 3777
IY K Q
Sbjct: 625 GIYFKLVTMQ 634
>gi|126930|sp|P23174|MDR3_CRIGR Multidrug resistance protein 3
(P-glycoprotein 3)
gi|2119778|pir||I48123 p-glycoprotein isoform III - Chinese hamster
gi|191169|gb|AAA68885.1| p-glycoprotein isoform III
Length = 1281
Score = 1024 bits (2647), Expect = 0.0
Identities = 559/1235 (45%), Positives = 777/1235 (62%), Gaps = 20/1235 (1%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLR-AQNSDFVVG--VDNVN 282
+F Y+ D L ++ GT+ A+ HG+G PL+ IV G MT F+ A N V + +N
Sbjct: 45 LFRYSDWQDKLFMLLGTIMAIAHGSGLPLMMIVFGEMTDKFVNNAGNFSLPVNFSLSMIN 104
Query: 283 PEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAI 462
P ++ E+ +Y YY LG + +Y+Q++ + A R + K+RQN+ AI
Sbjct: 105 PGRIL-------EEEMTRYAYYYSGLGGGVLVAAYIQVSFWTLAAGRQIKKIRQNFFHAI 157
Query: 463 LRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMT 642
LRQ++ WFD + T L RLTDD+ ++ EG+GDK + Q A F AG+ VGF W +T
Sbjct: 158 LRQEMGWFDIKGTTELNTRLTDDISKISEGIGDKVGMFFQAVATFFAGFIVGFIRGWKLT 217
Query: 643 LVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELD 822
LV+M +P++ LS A +K ++T + E YA AGA+AEE +IRTV + G +EL+
Sbjct: 218 LVIMAISPILGLSAAVWAKILSTFSDKELAAYAKAGAVAEEALGAIRTVIAFGGQNKELE 277
Query: 823 RFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTV 1002
R+ LE ++ GI K I +G + L +Y+SYALAFWYGSTL+I+ + G TV
Sbjct: 278 RYQKHLENAKKIGIKKAISANISMGIAFLLIYASYALAFWYGSTLVISKE-YTIGNAMTV 336
Query: 1003 FFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISF 1182
FF++L G+ S+G A P + +F ARGAA + +I+++PKID +S G D++KG++ F
Sbjct: 337 FFSILIGAFSVGQAAPCIDAFANARGAAYVIFDIIDNNPKIDSFSERGHKPDSIKGNLDF 396
Query: 1183 KDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLID 1362
DVHF YPSR +I +LKG++L++++G +ALVG+SGCGK+T + LLQR YDPT+G + ID
Sbjct: 397 SDVHFSYPSRANIKILKGLNLKVQSGQTVALVGNSGCGKTTTLQLLQRLYDPTEGTISID 456
Query: 1363 GVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIK 1542
G D+R NV LRE IG+VSQEPVLF TI ENI+ G + T +++ +A K ANA +FI
Sbjct: 457 GQDIRNFNVRYLREIIGVVSQEPVLFSTTIAENIRYGRGNVTMEEIKKAVKEANAYEFIM 516
Query: 1543 RLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALD 1722
+LP + T VGE+G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E EVQ ALD
Sbjct: 517 KLPQKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALD 576
Query: 1723 QAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXX 1902
+A+ GRTTI++AHRLST+RN D I F+ G IVE GSH ELM K+G+++ +
Sbjct: 577 KAREGRTTIVIAHRLSTVRNADVIAGFEDGVIVEQGSHSELMQKEGVYFKLVNMQTSGSQ 636
Query: 1903 XXEAGKDIEDTISESA--------HSHLXXXXXXXXXXXXXXXIHQLAEEVEECKA--PP 2052
++E + ++A SH+ H+L + +E A PP
Sbjct: 637 ILSQEFEVELSEEKAADGMTPNGWKSHIFRNSTKKSLKSSRAHHHRLDVDADELDANVPP 696
Query: 2053 TSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPAD----QMQANV 2220
S K+ K N + + ++ P +++ +E+ ++ P D Q + N+
Sbjct: 697 VSFLKVLKLNKTEWPYFVVGTVCAIVNGALQPAISIILSEMIAIFG-PGDDAVKQQKCNL 755
Query: 2221 YFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTG 2400
+ +F+ +G+ F FF G+ GE LT +LR AFK +LRQD++++DD ++ TG
Sbjct: 756 FSL--VFLGLGVLSFFTFFLQGFTFGKAGEILTTRLRSMAFKAMLRQDMSWFDDYKNSTG 813
Query: 2401 KLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGG 2577
L TR ATD V+ TRL ++ + + + I F YGWQ + G
Sbjct: 814 ALSTRLATDRAQVQGATGTRLALIAQNTANLGTGIIISFIYGWQLTLLLLSVVPFIAVSG 873
Query: 2578 YFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNL 2757
EM+M G RD + LE AGK+A++A+E+IRTV SL ++ +F Y E L EP+ ++
Sbjct: 874 IVEMKMLAGNAKRDKKALEAAGKIATEAIENIRTVVSLTQERKFESMYVEKLHEPYRNSV 933
Query: 2758 KHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTT 2937
+ AH YG F+ SQ+ ++F YA F G+ + M+ DV VF AI F +G+ +
Sbjct: 934 QMAHIYGITFSISQAFMYFSYAGCFRFGAYLIVNGHMRFRDVILVFSAIVFGAVALGHAS 993
Query: 2938 SFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGI-VKPITGNISIRNVFFNYPTRKDTKV 3114
SF PD KA+L+A+ LF L E IDS S G+ G+++ V FNYPTR + V
Sbjct: 994 SFAPDYAKAKLSAAHLFSLFERQPLIDSYSGEGLWPDKFEGSVTFNEVVFNYPTRANMPV 1053
Query: 3115 LQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQ 3294
LQG +L++K G+T+ALVG SGCGKST++ LLERFY+ G +++DG + LNI LR Q
Sbjct: 1054 LQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGTVLLDGQEAKKLNIQWLRAQ 1113
Query: 3295 VCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEK 3471
+ IVSQEP LFDC+I ENI YG N R V+ EIV AAK ANIH FI LP Y T VG+K
Sbjct: 1114 LGIVSQEPVLFDCSIAENIAYGDNSRVVSQDEIVRAAKAANIHPFIETLPQKYKTRVGDK 1173
Query: 3472 GTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAH 3651
GTQLSGGQKQR+AI RAL+R P VLLLDEATSALDTESEK+VQEALD A++GRTC+VIAH
Sbjct: 1174 GTQLSGGQKQRLAIRRALIRQPRVLLLDEATSALDTESEKVVQEALDKAREGRTCIVIAH 1233
Query: 3652 RLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIY 3756
RLSTIQN+D+I ++ GK+ E GTH +L+ + IY
Sbjct: 1234 RLSTIQNADLIVVIQNGKVKEHGTHQQLLAQKGIY 1268
Score = 423 bits (1087), Expect = e-116
Identities = 242/579 (41%), Positives = 344/579 (58%), Gaps = 4/579 (0%)
Frame = +1
Query: 151 ITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEV 330
+ GTV A+++GA P ++I+L M +F D V N LV
Sbjct: 714 VVGTVCAIVNGALQPAISIILSEMIAIF---GPGDDAVKQQKCNLFSLV----------- 759
Query: 331 VKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD--KQQTG 504
+L LGVL FFT ++Q F E L +LR KA+LRQ + WFD K TG
Sbjct: 760 ------FLGLGVLSFFTFFLQGFTFGKAGEILTTRLRSMAFKAMLRQDMSWFDDYKNSTG 813
Query: 505 NLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSG 684
L+ RL D +V+ G + AL+ Q A G + F Y W +TL+++ P I +SG
Sbjct: 814 ALSTRLATDRAQVQGATGTRLALIAQNTANLGTGIIISFIYGWQLTLLLLSVVPFIAVSG 873
Query: 685 AKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGI 864
K +A + +++ AG IA E +IRTV SL ++ + L + +
Sbjct: 874 IVEMKMLAGNAKRDKKALEAAGKIATEAIENIRTVVSLTQERKFESMYVEKLHEPYRNSV 933
Query: 865 VKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGA 1044
GI S MY SYA F +G+ LI+N R +I VF A++ G+ +LG A
Sbjct: 934 QMAHIYGITFSISQAFMYFSYAGCFRFGAYLIVNGHMRFRDVIL-VFSAIVFGAVALGHA 992
Query: 1045 LPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIH 1224
+ A+ +A+ + + P ID YS EG+ D +G ++F +V F YP+R ++
Sbjct: 993 SSFAPDYAKAKLSAAHLFSLFERQPLIDSYSGEGLWPDKFEGSVTFNEVVFNYPTRANMP 1052
Query: 1225 VLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLRE 1404
VL+G+SLE+K G +ALVGSSGCGKST+V LL+RFYDP G VL+DG + +++N+ LR
Sbjct: 1053 VLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGTVLLDGQEAKKLNIQWLRA 1112
Query: 1405 QIGIVSQEPVLFDGTIYENIKMGNEH--ATHDQVVEACKMANANDFIKRLPDGYGTRVGE 1578
Q+GIVSQEPVLFD +I ENI G+ + D++V A K AN + FI+ LP Y TRVG+
Sbjct: 1113 QLGIVSQEPVLFDCSIAENIAYGDNSRVVSQDEIVRAAKAANIHPFIETLPQKYKTRVGD 1172
Query: 1579 KGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVA 1758
KG QLSGGQKQR+AI RAL++ P++LLLDEATSALDTE+E+ VQ ALD+A+ GRT I++A
Sbjct: 1173 KGTQLSGGQKQRLAIRRALIRQPRVLLLDEATSALDTESEKVVQEALDKAREGRTCIVIA 1232
Query: 1759 HRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM 1875
HRLSTI+N D I V + G + E G+H++L++++GI++ M
Sbjct: 1233 HRLSTIQNADLIVVIQNGKVKEHGTHQQLLAQKGIYFSM 1271
Score = 338 bits (867), Expect = 6e-91
Identities = 212/531 (39%), Positives = 304/531 (56%), Gaps = 5/531 (0%)
Frame = +1
Query: 2200 DQMQANVYFWCGMF--VLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAF 2373
++M Y++ G+ VL+ V F+T A G + K+R F +LRQ++ +
Sbjct: 111 EEMTRYAYYYSGLGGGVLVAAYIQVSFWTLA-----AGRQIK-KIRQNFFHAILRQEMGW 164
Query: 2374 YDDLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXX 2550
+D GT +L TR D + + ++ + ++ T +GF GW+
Sbjct: 165 FDI--KGTTELNTRLTDDISKISEGIGDKVGMFFQAVATFFAGFIVGFIRGWKLTLVIMA 222
Query: 2551 XXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEY 2730
+ ++ ++ +AG VA +A+ IRTV + Q + Y ++
Sbjct: 223 ISPILGLSAAVWAKILSTFSDKELAAYAKAGAVAEEALGAIRTVIAFGGQNKELERYQKH 282
Query: 2731 LREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISF 2910
L +K A + + LI+ YA AF+ GS V + + VFF+I
Sbjct: 283 LENAKKIGIKKAISANISMGIAFLLIYASYALAFWYGSTLVISKEYTIGNAMTVFFSILI 342
Query: 2911 CGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKP--ITGNISIRNVFF 3084
+G I AR AA ++F +I++ IDS S+ G KP I GN+ +V F
Sbjct: 343 GAFSVGQAAPCIDAFANARGAAYVIFDIIDNNPKIDSFSERGH-KPDSIKGNLDFSDVHF 401
Query: 3085 NYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIR 3264
+YP+R + K+L+G L +++G+TVALVG+SGCGK+T + LL+R Y+ +G I IDG +IR
Sbjct: 402 SYPSRANIKILKGLNLKVQSGQTVALVGNSGCGKTTTLQLLQRLYDPTEGTISIDGQDIR 461
Query: 3265 NLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPD 3444
N N+ LRE + +VSQEP LF TI ENI YG NVT +EI +A K AN + FI+ LP
Sbjct: 462 NFNVRYLREIIGVVSQEPVLFSTTIAENIRYGRG-NVTMEEIKKAVKEANAYEFIMKLPQ 520
Query: 3445 GYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQ 3624
+DT VGE+G QLSGGQKQRIAIARALVR+P +LLLDEATSALDTESE VQ ALD A++
Sbjct: 521 KFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALDKARE 580
Query: 3625 GRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
GRT +VIAHRLST++N+DVIA +G IVE+G+H EL++K +Y K Q
Sbjct: 581 GRTTIVIAHRLSTVRNADVIAGFEDGVIVEQGSHSELMQKEGVYFKLVNMQ 631
>gi|9961250|ref|NP_061337.1| ATP-binding cassette, subfamily B, member
4 isoform B; P glycoprotein 3/multiple drug resistance 3;
P-glycoprotein-3/multiple drug resistance-3; multiple
drug resistance 3 [Homo sapiens]
Length = 1286
Score = 1019 bits (2634), Expect = 0.0
Identities = 566/1248 (45%), Positives = 774/1248 (61%), Gaps = 26/1248 (2%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFL-RAQNSDFVVG--VDNVN 282
+F Y+ D L + GT+ A+ HG+G PL+ IV G MT F+ A N F V + +N
Sbjct: 45 LFRYSDWQDKLFMSLGTIMAIAHGSGLPLMMIVFGEMTDKFVDTAGNFSFPVNFSLSLLN 104
Query: 283 PEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAI 462
P ++ E+ +Y YY LG + +Y+Q++ + A R + K+RQ + AI
Sbjct: 105 PGKIL-------EEEMTRYAYYYSGLGAGVLVAAYIQVSFWTLAAGRQIRKIRQKFFHAI 157
Query: 463 LRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMT 642
LRQ+I WFD T L RLTDD+ ++ EG+GDK + Q A F AG+ VGF W +T
Sbjct: 158 LRQEIGWFDINDTTELNTRLTDDISKISEGIGDKVGMFFQAVATFFAGFIVGFIRGWKLT 217
Query: 643 LVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELD 822
LV+M +P++ LS A +K ++ + E YA AGA+AEE +IRTV + G +EL+
Sbjct: 218 LVIMAISPILGLSAAVWAKILSAFSDKELAAYAKAGAVAEEALGAIRTVIAFGGQNKELE 277
Query: 823 RFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTV 1002
R+ LE ++ GI K I +G + L +Y+SYALAFWYGSTL+I+ + G TV
Sbjct: 278 RYQKHLENAKEIGIKKAISANISMGIAFLLIYASYALAFWYGSTLVISKE-YTIGNAMTV 336
Query: 1003 FFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISF 1182
FF++L G+ S+G A P + +F ARGAA + +I+++PKID +S G D++KG++ F
Sbjct: 337 FFSILIGAFSVGQAAPCIDAFANARGAAYVIFDIIDNNPKIDSFSERGHKPDSIKGNLEF 396
Query: 1183 KDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLID 1362
DVHF YPSR ++ +LKG++L++++G +ALVGSSGCGKST V L+QR YDP +G + ID
Sbjct: 397 NDVHFSYPSRANVKILKGLNLKVQSGQTVALVGSSGCGKSTTVQLIQRLYDPDEGTINID 456
Query: 1363 GVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIK 1542
G D+R NV+ LRE IG+VSQEPVLF TI ENI G + T D++ +A K ANA +FI
Sbjct: 457 GQDIRNFNVNYLREIIGVVSQEPVLFSTTIAENICYGRGNVTMDEIKKAVKEANAYEFIM 516
Query: 1543 RLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALD 1722
+LP + T VGE+G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E EVQ ALD
Sbjct: 517 KLPQKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALD 576
Query: 1723 QAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXX 1902
+A+ GRTTI++AHRLST+RN D I F+ G IVE GSH ELM K+G+++ +
Sbjct: 577 KAREGRTTIVIAHRLSTVRNADVIAGFEDGVIVEQGSHSELMKKEGVYFKLVNMQTSGSQ 636
Query: 1903 XXEAGKDIEDTISESA------HSHLXXXXXXXXXXXXXXXIHQLAEEVE--ECKAPPTS 2058
++ D + + S L L E + E PP S
Sbjct: 637 IQSEEFELNDEKAATRMAPNGWKSRLFRHSTQKNLKNSQMCQKSLDVETDGLEANVPPVS 696
Query: 2059 MFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPAD----QMQANVYF 2226
K+ K N + + + P F+++++EI ++ P D Q + N++
Sbjct: 697 FLKVLKLNKTEWPYFVVGTVCAIANGGLQPAFSVIFSEIIAIFG-PGDDAVKQQKCNIFS 755
Query: 2227 WCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKL 2406
+F+ +GI F FF G+ GE LT +LR AFK +LRQD++++DD ++ TG L
Sbjct: 756 L--IFLFLGIISFFTFFLQGFTFGKAGEILTRRLRSMAFKAMLRQDMSWFDDHKNSTGAL 813
Query: 2407 CTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYF 2583
TR ATDA V+ TRL ++ +I + + I F YGWQ + G
Sbjct: 814 STRLATDAAQVQGATGTRLALIAQNIANLGTGIIISFIYGWQLTLLLLAVVPIIAVSGIV 873
Query: 2584 EMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKH 2763
EM++ G RD + LE AGK+A++A+E+IRTV SL ++ +F Y E L P+ +++
Sbjct: 874 EMKLLAGNAKRDKKELEAAGKIATEAIENIRTVVSLTQERKFESMYVEKLYGPYRNSVQK 933
Query: 2764 AHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSF 2943
AH YG F+ SQ+ ++F YA F G+ + M+ DV VF AI F +G+ +SF
Sbjct: 934 AHIYGITFSISQAFMYFSYAGCFRFGAYLIVNGHMRFRDVILVFSAIVFGAVALGHASSF 993
Query: 2944 IPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKP--ITGNISIRNVFFNYPTRKDTKVL 3117
PD KA+L+A+ LF L E IDS S+ G+ KP GNI+ V FNYPTR + VL
Sbjct: 994 APDYAKAKLSAAHLFMLFERQPLIDSYSEEGL-KPDKFEGNITFNEVVFNYPTRANVPVL 1052
Query: 3118 QGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQ-------DKGMIMIDGDNIRNLNI 3276
QG +L++K G+T+ALVG SGCGKST++ LLERFY+ D G ++DG + LN+
Sbjct: 1053 QGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGTVFVDFGFQLLDGQEAKKLNV 1112
Query: 3277 SSLREQVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYD 3453
LR Q+ IVSQEP LFDC+I ENI YG N R V+ EIV AAK ANIH FI LP Y+
Sbjct: 1113 QWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVVSQDEIVSAAKAANIHPFIETLPHKYE 1172
Query: 3454 THVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRT 3633
T VG+KGTQLSGGQKQRIAIARAL+R P +LLLDEATSALDTESEK+VQEALD A++GRT
Sbjct: 1173 TRVGDKGTQLSGGQKQRIAIARALIRQPQILLLDEATSALDTESEKVVQEALDKAREGRT 1232
Query: 3634 CLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
C+VIAHRLSTIQN+D+I + G++ E GTH +L+ + IY Q
Sbjct: 1233 CIVIAHRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMVSVQ 1280
>gi|45382457|ref|NP_990225.1| ABC transporter protein [Gallus gallus]
gi|3355757|emb|CAA08835.1| ABC transporter protein; P-glycoprotein
[Gallus gallus]
Length = 1288
Score = 1014 bits (2621), Expect = 0.0
Identities = 551/1242 (44%), Positives = 774/1242 (61%), Gaps = 20/1242 (1%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F Y+ D LL+I G++ A+ HG P+ I+ G MT F+ + ++ +N
Sbjct: 50 LFRYSSCTDKLLMIFGSLLAIAHGTSLPIAMIIFGDMTDSFVTSGMTNITGNSSGLNSSA 109
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
V L+E E+ +Y YY + + +Y+Q + + A R V K+R+ + AI+RQ
Sbjct: 110 DVFNKLEE---EMTRYAYYYSAIAAAVLVAAYIQTSFWTLAAGRQVKKIREKFFHAIMRQ 166
Query: 472 QIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVM 651
+I WFD G L RL DD+ ++ EG+GDK L+Q FL G+ VGF W +TLV+
Sbjct: 167 EIGWFDVNDAGELNTRLIDDVSKINEGIGDKIGFLIQSETTFLTGFIVGFIRGWKLTLVI 226
Query: 652 MGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFY 831
+ +P++ LS A +K + T EQ YA AGA+AEE S++RTV + G ++E+ R++
Sbjct: 227 LAVSPVLGLSAALWAKILTAFTDKEQAAYAKAGAVAEEVLSAVRTVIAFGGQEKEIKRYH 286
Query: 832 NALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFA 1011
LE ++ GI K I +G + L +Y+SYALAFWYG+TLI+ + + G + TVFF+
Sbjct: 287 KNLEDAKRIGIRKAITSNISMGAAFLLIYASYALAFWYGTTLILANE-YSIGNVLTVFFS 345
Query: 1012 VLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDV 1191
VL G+ S+G P + +F ARGAA + +I++ P+ID YS G D++KG++ F++V
Sbjct: 346 VLIGAFSIGQTAPSIEAFANARGAAYAIFNIIDNEPEIDSYSDAGHKPDHIKGNLEFQNV 405
Query: 1192 HFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVD 1371
F YPSR D+ +LKG++L++ G +ALVG SGCGKST V L+QRFYDP +G + IDG D
Sbjct: 406 FFNYPSRPDVEILKGLNLKVNCGQTVALVGGSGCGKSTTVQLIQRFYDPKEGTITIDGQD 465
Query: 1372 LREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLP 1551
L+ +NV LRE IG+V+QEPVLF TI ENI+ G E T +++ A K ANA DFI +LP
Sbjct: 466 LKSLNVRYLREIIGVVNQEPVLFATTIAENIRYGREDVTMEEIERATKEANAYDFIMKLP 525
Query: 1552 DGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQ 1731
+ T VGE+G Q+SGGQKQRIAIARALV NPKILLLDEATSALDTE+E VQ ALD+A+
Sbjct: 526 KKFETVVGERGAQMSGGQKQRIAIARALVHNPKILLLDEATSALDTESESVVQAALDKAR 585
Query: 1732 AGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXXE 1911
GRTT++VAHRLST+RN D I VF++G I E G+H +L+ K+GI+Y +
Sbjct: 586 EGRTTVVVAHRLSTVRNADLIAVFESGVITEQGNHSQLIEKKGIYYKLVNMQTIETEDPS 645
Query: 1912 AGKDIEDTIS---ESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEEC---------KAPPT 2055
+ K E+ +S + S+L + E + + PP
Sbjct: 646 SEKS-ENAVSVKRSGSQSNLDESLKKELRRGSTRRSMKKPGEPNDTDEKGSSPDEELPPV 704
Query: 2056 SMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQM----QANVY 2223
S K+ K N ++ + ++ P F+++++EI ++S DQ ++N+Y
Sbjct: 705 SFLKLMKLNKNEWPYFVAGTFCAIVNGALQPAFSVIFSEIIGIFS-ETDQKVLREKSNLY 763
Query: 2224 FWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGK 2403
+F+ +GI F FF G+ GE LTMKLRF AFK +LRQD+A++DD ++ TG
Sbjct: 764 SL--LFLALGIISFFTFFVQGFAFGKAGEILTMKLRFMAFKAMLRQDMAWFDDPKNSTGA 821
Query: 2404 LCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGY 2580
L TR A DA V+ RL ++ +I + + I YGWQ + G
Sbjct: 822 LTTRLANDASQVKGATGVRLALIAQNIANLGTGIIISLVYGWQLTLLLLAVVPIIAVAGM 881
Query: 2581 FEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLK 2760
EM+M G +D LE AGK+A++A+E+IRTV SL R+++F Y E+L P+ ++K
Sbjct: 882 IEMKMLAGHAKKDKIELEAAGKIATEAIENIRTVASLTREKRFELMYGEHLLVPYRNSVK 941
Query: 2761 HAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTS 2940
AH +G F+ SQ+++FF YA F G+ V ++ V+ VF A+ F +G T+S
Sbjct: 942 KAHIFGFCFSLSQAMMFFTYAGCFRFGAYLVVNGHIEYKTVFLVFSAVVFGAMALGQTSS 1001
Query: 2941 FIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKP--ITGNISIRNVFFNYPTRKDTKV 3114
F PD KA+++A+ LF L PIDS + G KP GN I++V FNYP R + K+
Sbjct: 1002 FAPDYAKAKISAAHLFVLFNRVPPIDSYREDG-EKPEKFGGNTRIKDVKFNYPNRPEVKI 1060
Query: 3115 LQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQ 3294
LQG L ++ G+T+ALVG SGCGKST++ LLERFY+ G I+ D + + LNI LR
Sbjct: 1061 LQGLNLAVEKGETLALVGSSGCGKSTVVQLLERFYDPLSGEIVFDDIDAKTLNIQWLRSH 1120
Query: 3295 VCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEK 3471
+ IVSQEP LFD TI ENI YG N R V+++EI+ AAK A+IH+FI LP+ Y+T VG+K
Sbjct: 1121 IGIVSQEPILFDFTIAENIAYGDNSREVSHEEIISAAKAASIHSFIDSLPEKYNTRVGDK 1180
Query: 3472 GTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAH 3651
GTQLSGGQKQRIAIARAL+R P +LLLDEATSALDTESEKIVQEALD A++GRTC+VIAH
Sbjct: 1181 GTQLSGGQKQRIAIARALIRKPQILLLDEATSALDTESEKIVQEALDKAREGRTCIVIAH 1240
Query: 3652 RLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
RLSTIQN+D IA++ GK++E+GTH +L+ + Y Q
Sbjct: 1241 RLSTIQNADKIAVIQNGKVIEQGTHQQLLAEKGFYYSLVNVQ 1282
Score = 340 bits (873), Expect = 1e-91
Identities = 208/544 (38%), Positives = 309/544 (56%), Gaps = 5/544 (0%)
Frame = +1
Query: 2167 AEIFNVYSLPADQMQANVYFWCGMFVLMGITFFV--GFFTSANCLGRCGESLTMKLRFEA 2340
A++FN ++M Y++ + + + ++ F+T A GR K+R +
Sbjct: 109 ADVFNKLE---EEMTRYAYYYSAIAAAVLVAAYIQTSFWTLA--AGR----QVKKIREKF 159
Query: 2341 FKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIVTICGALGIGFY 2517
F ++RQ+I ++D + G+L TR D + + ++ ++ S T +GF
Sbjct: 160 FHAIMRQEIGWFDV--NDAGELNTRLIDDVSKINEGIGDKIGFLIQSETTFLTGFIVGFI 217
Query: 2518 YGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNR 2697
GW+ + ++ ++ +AG VA + + +RTV +
Sbjct: 218 RGWKLTLVILAVSPVLGLSAALWAKILTAFTDKEQAAYAKAGAVAEEVLSAVRTVIAFGG 277
Query: 2698 QEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPI 2877
QE+ Y + L + ++ A T + LI+ YA AF+ G+ +
Sbjct: 278 QEKEIKRYHKNLEDAKRIGIRKAITSNISMGAAFLLIYASYALAFWYGTTLILANEYSIG 337
Query: 2878 DVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKP--I 3051
+V VFF++ IG T I AR AA +F +I++ IDS SD+G KP I
Sbjct: 338 NVLTVFFSVLIGAFSIGQTAPSIEAFANARGAAYAIFNIIDNEPEIDSYSDAGH-KPDHI 396
Query: 3052 TGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDK 3231
GN+ +NVFFNYP+R D ++L+G L + G+TVALVG SGCGKST + L++RFY+ +
Sbjct: 397 KGNLEFQNVFFNYPSRPDVEILKGLNLKVNCGQTVALVGGSGCGKSTTVQLIQRFYDPKE 456
Query: 3232 GMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMA 3411
G I IDG ++++LN+ LRE + +V+QEP LF TI ENI YG +VT +EI A K A
Sbjct: 457 GTITIDGQDLKSLNVRYLREIIGVVNQEPVLFATTIAENIRYG-REDVTMEEIERATKEA 515
Query: 3412 NIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEK 3591
N ++FI+ LP ++T VGE+G Q+SGGQKQRIAIARALV +P +LLLDEATSALDTESE
Sbjct: 516 NAYDFIMKLPKKFETVVGERGAQMSGGQKQRIAIARALVHNPKILLLDEATSALDTESES 575
Query: 3592 IVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCE 3771
+VQ ALD A++GRT +V+AHRLST++N+D+IA+ G I E+G H +LI K IY K
Sbjct: 576 VVQAALDKAREGRTTVVVAHRLSTVRNADLIAVFESGVITEQGNHSQLIEKKGIYYKLVN 635
Query: 3772 TQRI 3783
Q I
Sbjct: 636 MQTI 639
>gi|6981354|ref|NP_036822.1| ATP-binding cassette, sub-family B
(MDR/TAP), member 4; ATP-binding cassette, sub-family B
(MDR/TAP), member 4 (P-glycoprotein 3/ multidrug
resistance 2); ATP-binding cassette sub-family B
(MDR/TAP) member 4 (P-glycoprotein 3/ multidrug
resistance 2); P-glycoprotein 3/ multidrug resistance 2;
ATP-binding cassette sub-family B (MDR/TAP) member 4
(P-glycoprotein 3/ multidrug resistance 2 [Rattus
norvegicus]
gi|1170903|sp|Q08201|MDR2_RAT Multidrug resistance protein 2
(P-glycoprotein 2)
gi|543425|pir||S41646 p-glycoprotein - rat
gi|310193|gb|AAA02937.1| P-glycoprotein
Length = 1278
Score = 1013 bits (2620), Expect = 0.0
Identities = 558/1235 (45%), Positives = 768/1235 (62%), Gaps = 20/1235 (1%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFL-RAQNSDFVVG--VDNVN 282
+F Y+ D L ++ GT A+ HG+G PL+ IV G MT F+ A N V + +N
Sbjct: 42 LFRYSDWQDKLFMLLGTAMAIAHGSGLPLMMIVFGEMTDKFVDNAGNFSLPVNFSLSMLN 101
Query: 283 PEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAI 462
P ++ E+ +Y YY LG + +Y+Q++ + A R + K+RQ + AI
Sbjct: 102 PGRIL-------EEEMTRYAYYYSGLGGGVLLAAYIQVSFWTLAAGRQIRKIRQKFFHAI 154
Query: 463 LRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMT 642
LRQ++ WFD + T L RLTDD+ ++ EG+GDK + Q A F AG+ VGF W +T
Sbjct: 155 LRQEMGWFDIKGTTELNTRLTDDISKISEGIGDKVGMFFQAIATFFAGFIVGFIRGWKLT 214
Query: 643 LVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELD 822
LV+M ++ LS A +K ++T + E YA AGA+AEE +IRTV + G +EL+
Sbjct: 215 LVIMAITAILGLSTAVWAKILSTFSDKELAAYAKAGAVAEEALGAIRTVIAFGGQNKELE 274
Query: 823 RFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTV 1002
R+ LE ++ GI K I +G + L +Y+SYALAFWYGSTL+I+ + G TV
Sbjct: 275 RYQKHLENAKKIGIKKAISANISMGIAFLLIYASYALAFWYGSTLVISKE-YTIGNAMTV 333
Query: 1003 FFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISF 1182
FF++L G+ S+G A P + +F ARGAA + +I+++PKID +S G D++KG++ F
Sbjct: 334 FFSILIGAFSVGQAAPCIDAFPNARGAAYVIFDIIDNNPKIDSFSERGHKPDSIKGNLEF 393
Query: 1183 KDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLID 1362
DVHF YPSR +I +LKG++L++K+G +ALVG+SGCGKST V LLQR YDPT+G + ID
Sbjct: 394 SDVHFSYPSRANIKILKGLNLKVKSGQTVALVGNSGCGKSTTVQLLQRLYDPTEGTISID 453
Query: 1363 GVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIK 1542
G D+R NV LRE IG+VSQEPVLF TI ENI+ G + T D++ +A K ANA DFI
Sbjct: 454 GQDIRNFNVRCLREFIGVVSQEPVLFSTTIAENIRYGRGNVTMDEIKKAVKEANAYDFIM 513
Query: 1543 RLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALD 1722
+LP + T VG++G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E EVQ ALD
Sbjct: 514 KLPQKFDTLVGDRGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALD 573
Query: 1723 QAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXX 1902
+A+ GRTTI++AHRLST+RN D I F+ G IVE GSH EL+ K+GI++ +
Sbjct: 574 KAREGRTTIVIAHRLSTVRNADVIAGFEDGVIVEQGSHSELIKKEGIYFRLVNMQTSGSQ 633
Query: 1903 XXEAGKDIEDTISESAHS------HLXXXXXXXXXXXXXXXIHQLAEEVE----ECKAPP 2052
++E + ++A HQ +VE + PP
Sbjct: 634 ILSEEFEVELSDEKAAGGVAPNGWKARIFRNSTKKSLKSSRAHQNRLDVETNELDANVPP 693
Query: 2053 TSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANVYFWC 2232
S K+ + N + + ++ P F+++ +E+ ++ D ++ C
Sbjct: 694 VSFLKVLRLNKTEWPYFVVGTLCAIANGALQPAFSIILSEMIAIFGPGDDTVKQQK---C 750
Query: 2233 GMFVL----MGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTG 2400
MF L +G+ F FF G+ GE LT +LR AFK +LRQD++++DD ++ TG
Sbjct: 751 NMFSLVFLGLGVHSFFTFFLQGFTFGKAGEILTTRLRSMAFKAMLRQDMSWFDDHKNSTG 810
Query: 2401 KLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGG 2577
L TR ATDA V+ TRL ++ + + + I F YGWQ + G
Sbjct: 811 ALSTRLATDAAQVQGATGTRLALIAQNTANLGTGIIISFIYGWQLTLLLLSVVPFIAVAG 870
Query: 2578 YFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNL 2757
EM+M G RD + +E AGK+A++A+E+IRTV SL ++ +F Y E L P+ ++
Sbjct: 871 IVEMKMLAGNAKRDKKEMEAAGKIATEAIENIRTVVSLTQERKFESMYVEKLHGPYRNSV 930
Query: 2758 KHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTT 2937
+ AH YG F+ SQ+ ++F YA F GS + M+ DV VF AI +G+ +
Sbjct: 931 RKAHIYGITFSISQAFMYFSYAGCFRFGSYLIVNGHMRFKDVILVFSAIVLGAVALGHAS 990
Query: 2938 SFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGI-VKPITGNISIRNVFFNYPTRKDTKV 3114
SF PD KA+L+A+ LF L E IDS S G+ G+++ V FNYPTR + V
Sbjct: 991 SFAPDYAKAKLSAAYLFSLFERQPLIDSYSREGMWPDKFEGSVTFNEVVFNYPTRANVPV 1050
Query: 3115 LQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQ 3294
LQG +L++K G+T+ALVG SGCGKST++ LLERFY+ G +++DG + LN+ LR Q
Sbjct: 1051 LQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGTVLLDGQEAKKLNVQWLRAQ 1110
Query: 3295 VCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEK 3471
+ IVSQEP LFDC+I +NI YG N R V+ EIV AAK ANIH FI LP Y+T VG+K
Sbjct: 1111 LGIVSQEPILFDCSIAKNIAYGDNSRVVSQDEIVRAAKEANIHPFIETLPQKYETRVGDK 1170
Query: 3472 GTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAH 3651
GTQLSGGQKQRIAIARAL+R P VLLLDEATSALDTESEK+VQEALD A++GRTC+VIAH
Sbjct: 1171 GTQLSGGQKQRIAIARALIRQPRVLLLDEATSALDTESEKVVQEALDKAREGRTCIVIAH 1230
Query: 3652 RLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIY 3756
RLSTIQN+D+I ++ GK+ E GTH +L+ + IY
Sbjct: 1231 RLSTIQNADLIVVIDNGKVKEHGTHQQLLAQKGIY 1265
Score = 419 bits (1077), Expect = e-115
Identities = 241/579 (41%), Positives = 343/579 (58%), Gaps = 4/579 (0%)
Frame = +1
Query: 151 ITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEV 330
+ GT+ A+ +GA P +I+L M +F G D V + SL
Sbjct: 711 VVGTLCAIANGALQPAFSIILSEMIAIF--------GPGDDTVKQQKCNMFSL------- 755
Query: 331 VKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD--KQQTG 504
+L LGV FFT ++Q F E L +LR KA+LRQ + WFD K TG
Sbjct: 756 -----VFLGLGVHSFFTFFLQGFTFGKAGEILTTRLRSMAFKAMLRQDMSWFDDHKNSTG 810
Query: 505 NLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSG 684
L+ RL D +V+ G + AL+ Q A G + F Y W +TL+++ P I ++G
Sbjct: 811 ALSTRLATDAAQVQGATGTRLALIAQNTANLGTGIIISFIYGWQLTLLLLSVVPFIAVAG 870
Query: 685 AKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGI 864
K +A + +++ AG IA E +IRTV SL ++ + L + +
Sbjct: 871 IVEMKMLAGNAKRDKKEMEAAGKIATEAIENIRTVVSLTQERKFESMYVEKLHGPYRNSV 930
Query: 865 VKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGA 1044
K GI S MY SYA F +GS LI+N + +I VF A++ G+ +LG A
Sbjct: 931 RKAHIYGITFSISQAFMYFSYAGCFRFGSYLIVNGHMRFKDVIL-VFSAIVLGAVALGHA 989
Query: 1045 LPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIH 1224
+ A+ +A+ + + P ID YS EG+ D +G ++F +V F YP+R ++
Sbjct: 990 SSFAPDYAKAKLSAAYLFSLFERQPLIDSYSREGMWPDKFEGSVTFNEVVFNYPTRANVP 1049
Query: 1225 VLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLRE 1404
VL+G+SLE+K G +ALVGSSGCGKST+V LL+RFYDP G VL+DG + +++NV LR
Sbjct: 1050 VLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGTVLLDGQEAKKLNVQWLRA 1109
Query: 1405 QIGIVSQEPVLFDGTIYENIKMGNEH--ATHDQVVEACKMANANDFIKRLPDGYGTRVGE 1578
Q+GIVSQEP+LFD +I +NI G+ + D++V A K AN + FI+ LP Y TRVG+
Sbjct: 1110 QLGIVSQEPILFDCSIAKNIAYGDNSRVVSQDEIVRAAKEANIHPFIETLPQKYETRVGD 1169
Query: 1579 KGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVA 1758
KG QLSGGQKQRIAIARAL++ P++LLLDEATSALDTE+E+ VQ ALD+A+ GRT I++A
Sbjct: 1170 KGTQLSGGQKQRIAIARALIRQPRVLLLDEATSALDTESEKVVQEALDKAREGRTCIVIA 1229
Query: 1759 HRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM 1875
HRLSTI+N D I V G + E G+H++L++++GI++ M
Sbjct: 1230 HRLSTIQNADLIVVIDNGKVKEHGTHQQLLAQKGIYFSM 1268
Score = 340 bits (873), Expect = 1e-91
Identities = 215/531 (40%), Positives = 305/531 (56%), Gaps = 5/531 (0%)
Frame = +1
Query: 2200 DQMQANVYFWCGMF--VLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAF 2373
++M Y++ G+ VL+ V F+T A G + K+R + F +LRQ++ +
Sbjct: 108 EEMTRYAYYYSGLGGGVLLAAYIQVSFWTLA-----AGRQIR-KIRQKFFHAILRQEMGW 161
Query: 2374 YDDLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXX 2550
+D GT +L TR D + + ++ + +I T +GF GW+
Sbjct: 162 FDI--KGTTELNTRLTDDISKISEGIGDKVGMFFQAIATFFAGFIVGFIRGWKLTLVIMA 219
Query: 2551 XXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEY 2730
+ ++ ++ +AG VA +A+ IRTV + Q + Y ++
Sbjct: 220 ITAILGLSTAVWAKILSTFSDKELAAYAKAGAVAEEALGAIRTVIAFGGQNKELERYQKH 279
Query: 2731 LREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISF 2910
L +K A + + LI+ YA AF+ GS V + + VFF+I
Sbjct: 280 LENAKKIGIKKAISANISMGIAFLLIYASYALAFWYGSTLVISKEYTIGNAMTVFFSILI 339
Query: 2911 CGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKP--ITGNISIRNVFF 3084
+G I AR AA ++F +I++ IDS S+ G KP I GN+ +V F
Sbjct: 340 GAFSVGQAAPCIDAFPNARGAAYVIFDIIDNNPKIDSFSERGH-KPDSIKGNLEFSDVHF 398
Query: 3085 NYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIR 3264
+YP+R + K+L+G L +K+G+TVALVG+SGCGKST + LL+R Y+ +G I IDG +IR
Sbjct: 399 SYPSRANIKILKGLNLKVKSGQTVALVGNSGCGKSTTVQLLQRLYDPTEGTISIDGQDIR 458
Query: 3265 NLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPD 3444
N N+ LRE + +VSQEP LF TI ENI YG NVT EI +A K AN ++FI+ LP
Sbjct: 459 NFNVRCLREFIGVVSQEPVLFSTTIAENIRYGRG-NVTMDEIKKAVKEANAYDFIMKLPQ 517
Query: 3445 GYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQ 3624
+DT VG++G QLSGGQKQRIAIARALVR+P +LLLDEATSALDTESE VQ ALD A++
Sbjct: 518 KFDTLVGDRGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALDKARE 577
Query: 3625 GRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
GRT +VIAHRLST++N+DVIA +G IVE+G+H ELI+K IY + Q
Sbjct: 578 GRTTIVIAHRLSTVRNADVIAGFEDGVIVEQGSHSELIKKEGIYFRLVNMQ 628
>gi|48267183|gb|AAQ63650.3| multi-drug resistance P-glycoprotein 1;
PGY1; MDR1; GP170; ABC20; P-GP [Oryctolagus cuniculus]
Length = 1279
Score = 1008 bits (2606), Expect = 0.0
Identities = 547/1242 (44%), Positives = 780/1242 (62%), Gaps = 18/1242 (1%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNP 285
+ +F Y+ +D L ++ GT+AA+IHGA PL+ +V G MT F N + N+N
Sbjct: 35 FAMFRYSNWLDKLYMVVGTLAAIIHGAALPLMMLVFGDMTDSFSNPGNM-IPANITNLNM 93
Query: 286 EGLVPISLDE-FNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAI 462
+ + E E+ Y YY +G + +Y+Q++ + A R K+R+ + +I
Sbjct: 94 SNISASEIYEHLEEEMTTYAYYYSGIGAGVLVAAYIQVSFWCLAAGRQTFKIRKQFFHSI 153
Query: 463 LRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMT 642
+RQ+I WFD G L RLTDD+ ++ +G+GDK + Q + F G+ VGF W +T
Sbjct: 154 MRQEIGWFDVHDVGELNTRLTDDVSKINDGIGDKIGMFFQSMSTFFTGFIVGFTRGWKLT 213
Query: 643 LVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELD 822
LV++ +P++ LS A +K M++ T E YA AGA+AEE ++IRTV + G ++EL+
Sbjct: 214 LVILAISPVLGLSAALWAKIMSSFTDKELLAYAKAGAVAEEVLAAIRTVIAFGGQQKELE 273
Query: 823 RFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTV 1002
R+ LE ++ GI K I VG + L MY+SYALAFWY + L + + G + TV
Sbjct: 274 RYNKNLEEAKRIGIKKAITANISVGVAFLLMYASYALAFWYWNHLG-HLKEYSIGQVLTV 332
Query: 1003 FFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISF 1182
FF+VL G+ S+G A P++ +F ARGAA + R+I++ P ID YS G DN+KG++ F
Sbjct: 333 FFSVLVGAFSIGQASPNVEAFANARGAAYEIFRIIDNMPSIDSYSEAGHKPDNIKGNLEF 392
Query: 1183 KDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLID 1362
++VHF YPSRK++ +LKG++L++++G +ALVG+SGCGKST V L++R YDPT G V ID
Sbjct: 393 RNVHFSYPSRKEVKILKGLNLKVESGQTVALVGNSGCGKSTTVQLMRRLYDPTDGVVSID 452
Query: 1363 GVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIK 1542
G D+R +NV LRE G+VSQEPVLF TI EN++ G E T D++ +A K ANA +FI
Sbjct: 453 GQDIRTMNVRYLREITGVVSQEPVLFATTIAENVRYGREDVTMDEIEKAVKEANAYNFIM 512
Query: 1543 RLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALD 1722
+LP + T VGE+G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E VQ ALD
Sbjct: 513 KLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVALD 572
Query: 1723 QAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFY----------D 1872
+A+ GRTTI++AHRLST+RN D I F G IVE G+HEELM ++G+++ +
Sbjct: 573 KARKGRTTIVIAHRLSTVRNADVIAGFDNGVIVERGNHEELMRQKGVYFRLVTMQTAGNE 632
Query: 1873 MTXXXXXXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAE-EVEECKAP 2049
+ E +E + ES S + +L+ E + P
Sbjct: 633 IDLENSASESRGEKMDLVEMSAKESGSSLIRRRSSHKSFHGAQGQDGKLSTTEAQNENVP 692
Query: 2050 PTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQ--MQANVY 2223
P S ++I K N + + + P FA+V+++I V++ D + N
Sbjct: 693 PVSFWRIMKLNLTEWPYFLVGVICAIINGGLQPAFAVVFSKIVGVFTRNDDDETKRRNSD 752
Query: 2224 FWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGK 2403
+ +F+++GI F+ FF G+ GE LT +LR+ FK++LRQD++++DD ++ TG
Sbjct: 753 LFSLLFLILGIISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDDPKNTTGA 812
Query: 2404 LCTRFATDAPNVRYVF-TRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGY 2580
L TR A DA V+ +RL V+ +I + + I YGWQ + G
Sbjct: 813 LTTRLANDAAQVKGATGSRLAVIAQNIANLGTGIIISLVYGWQLTLLLLAIVPIIAIAGV 872
Query: 2581 FEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLK 2760
EM+M G+ ++D + LE +GK+A++A+E+ RTV SL R+++F Y + L+ P+ +L+
Sbjct: 873 VEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTREQKFENMYAQSLQVPYRNSLE 932
Query: 2761 HAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTS 2940
AH +G F+F+Q++++F YA F G+ V ++ M +V VF A+ F +G +S
Sbjct: 933 KAHIFGITFSFTQAMMYFSYAGCFRFGAFLVARELMSFENVLLVFSAVVFGAMAVGQVSS 992
Query: 2941 FIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPIT--GNISIRNVFFNYPTRKDTKV 3114
F PD KA+++AS + ++E IDS S G+ KP T GN++ ++V FNYPTR D V
Sbjct: 993 FAPDYAKAKISASHIIMILEKLPKIDSYSTEGL-KPGTLEGNMTFKDVVFNYPTRPDIPV 1051
Query: 3115 LQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQ 3294
LQG L +K G+T+ALVG SGCGKST++ L+ERFY+ G +++DG + LN+ LR
Sbjct: 1052 LQGLNLQVKKGQTLALVGPSGCGKSTVVQLIERFYDPLAGTVLLDGKEVNQLNVQWLRAH 1111
Query: 3295 VCIVSQEPTLFDCTIGENICYGTNRNVTYQ-EIVEAAKMANIHNFILGLPDGYDTHVGEK 3471
+ IVSQEP LFDC+I ENI YG N V Q EI++AAK ANIH FI LPD Y+T VG+K
Sbjct: 1112 LGIVSQEPILFDCSIAENIAYGDNSRVVSQDEIIKAAKEANIHAFIDSLPDKYNTRVGDK 1171
Query: 3472 GTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAH 3651
GTQLSGGQKQRIAIARALVR P +LLLDEATSA DTESEK+VQEALD A++GRTC+VIAH
Sbjct: 1172 GTQLSGGQKQRIAIARALVRQPHILLLDEATSAPDTESEKVVQEALDKAREGRTCVVIAH 1231
Query: 3652 RLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
RLSTIQN+D+I + G++ E GTH +L+ + IY Q
Sbjct: 1232 RLSTIQNADMIVVFQNGRVKECGTHHQLLAQKGIYFSMVSVQ 1273
>gi|191157|gb|AAA37005.1| p-glycoprotein
Length = 1169
Score = 1004 bits (2596), Expect = 0.0
Identities = 533/1164 (45%), Positives = 749/1164 (63%), Gaps = 17/1164 (1%)
Frame = +1
Query: 337 YCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTA 516
Y YY +G + +Y+Q++ + A R +HK+RQ + AI+ Q+I WFD G L
Sbjct: 4 YAYYYTGIGAGVLIVAYIQVSFWCLAAGRQIHKIRQKFFHAIMNQEIGWFDVHDVGELNT 63
Query: 517 RLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMS 696
RLTDD+ ++ EG+GDK + Q A F G+ +GF W +TLV++ +P++ LS +
Sbjct: 64 RLTDDVSKINEGIGDKIGMFFQAMATFFGGFIIGFTRGWKLTLVILAISPVLGLSAGIWA 123
Query: 697 KSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYC 876
K +++ T E + YA AGA+AEE ++IRTV + G K+EL+R+ N LE ++ GI K
Sbjct: 124 KILSSFTDKELQAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNNNLEEAKRLGIKKAI 183
Query: 877 YMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHL 1056
I +G + L +Y+SYALAFWYG++L+I+ + G + TVFFAVL S+G A P++
Sbjct: 184 TANISMGAAFLLIYASYALAFWYGTSLVISKE-YSIGQVLTVFFAVLIAPFSIGQASPNI 242
Query: 1057 ASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKG 1236
+F ARGAA + +I++ P ID +S G DN+KG++ FK++HF YPSRKD+ +LKG
Sbjct: 243 EAFANARGAAYEIFNIIDNKPSIDSFSKNGYKPDNIKGNLEFKNIHFSYPSRKDVQILKG 302
Query: 1237 ISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGI 1416
++L++++G +ALVG+SGCGKST V LLQR YDPT+G V IDG D+R +NV LRE IG+
Sbjct: 303 LNLKVQSGQTVALVGNSGCGKSTTVQLLQRLYDPTEGVVSIDGQDIRTINVRYLREIIGV 362
Query: 1417 VSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLS 1596
VSQEPVLF TI ENI+ G E+ T D++ +A K ANA DFI +LP + T VGE+G QLS
Sbjct: 363 VSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLS 422
Query: 1597 GGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTI 1776
GGQKQRIAIARALV+NPKILLLDEATSALDTE+E VQ ALD+A+ GRTTI++AHRLST+
Sbjct: 423 GGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTV 482
Query: 1777 RNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXXEAGKDIEDTISE---- 1944
RN D I F G IVE G+HEELM ++GI++ + E G ++ ++ +E
Sbjct: 483 RNADIIAGFDGGVIVEQGNHEELMREKGIYFKLV-MTQTAGNEIELGNEVGESKNEIDNL 541
Query: 1945 ------SAHSHLXXXXXXXXXXXXXXXIHQLA-EEVEECKAPPTSMFKIFKFNGDKVGWX 2103
SA S + +L+ +E + PP S ++I K N + +
Sbjct: 542 DMSSKDSASSLIRRRSTRRSIRGPHDQDRKLSTKEALDEDVPPISFWRILKLNSSEWPYF 601
Query: 2104 XXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQ--MQANVYFWCGMFVLMGITFFVGFF 2277
++ P F+++++++ V++ D + + + +F+++G+ F+ FF
Sbjct: 602 VVGIFCAIVNGALQPAFSIIFSKVVGVFTRNTDDETKRHDSNLFSLLFLILGVISFITFF 661
Query: 2278 TSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVR-YVFT 2454
G+ GE LT +LR+ FK++LRQD++++D+ ++ TG L TR A DA V+
Sbjct: 662 LQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDNPKNTTGALTTRLANDAGQVKGATGA 721
Query: 2455 RLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLE 2634
RL V+ +I + + I YGWQ + G EM+M G+ ++D + LE
Sbjct: 722 RLAVITQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELE 781
Query: 2635 EAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFF 2814
+GK+A++A+E+ RTV SL R+++F Y + L+ P+ LK AH +G F+F+Q++++F
Sbjct: 782 GSGKIATEAIENFRTVVSLTREQKFENMYAQSLQIPYRNALKKAHVFGITFSFTQAMMYF 841
Query: 2815 MYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYL 2994
YAA F G+ V ++ M +V VF AI F +G +SF PD KA+++AS + +
Sbjct: 842 SYAACFRFGAYLVARELMTFENVLLVFSAIVFGAMAVGQVSSFAPDYAKAKVSASHIIMI 901
Query: 2995 IEHPTPIDSLSDSGIVKPIT--GNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVG 3168
IE IDS S G+ KP T GN+ V FNYPTR D VLQG L++K G+T+ALVG
Sbjct: 902 IEKVPSIDSYSTGGL-KPNTLEGNVKFNEVVFNYPTRPDIPVLQGLNLEVKKGQTLALVG 960
Query: 3169 HSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGEN 3348
SGCGKST++ LLERFY+ G + +DG + LN+ LR + IVSQEP LFDC+I EN
Sbjct: 961 SSGCGKSTVVQLLERFYDPMAGTVFLDGKEVNQLNVQWLRAHLGIVSQEPILFDCSIAEN 1020
Query: 3349 ICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARAL 3525
I YG N R V+ EI AAK ANIH FI LPD Y+T VG+KGTQLSGGQKQRIAIARAL
Sbjct: 1021 IAYGDNSRVVSQDEIERAAKEANIHQFIESLPDKYNTRVGDKGTQLSGGQKQRIAIARAL 1080
Query: 3526 VRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGK 3705
VR P +LLLDEATSALDTESEK+VQEALD A++GRTC+VIAHRLSTIQN+D+I ++ GK
Sbjct: 1081 VRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVIQNGK 1140
Query: 3706 IVEKGTHDELIRKSEIYQKFCETQ 3777
+ E GTH +L+ + IY Q
Sbjct: 1141 VKEHGTHQQLLAQKGIYFSMVSVQ 1164
>gi|40644181|emb|CAC86600.1| multidrug resistance protein [Platichthys
flesus]
Length = 1292
Score = 1003 bits (2594), Expect = 0.0
Identities = 539/1242 (43%), Positives = 771/1242 (61%), Gaps = 20/1242 (1%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F + +D+ +++ GTV A+ +G PL+ IV G MT + + + P
Sbjct: 49 VFRFADSLDIFMILCGTVMAMANGVVLPLMCIVFGDMTDSLVNFPTGEISDNFTVIYPNF 108
Query: 292 L-VPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILR 468
+PI+ ++ +Y IYY ++G + +Y+Q++ + A R V ++R+ + I++
Sbjct: 109 TGLPIN-STLQEDMNRYAIYYSIMGATVLVAAYLQVSLWTMAAGRQVKRIRKLFFHRIMQ 167
Query: 469 QQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLV 648
Q I WFD +TG L RL DD+ +++EG+GDK A+L+Q + FL+ + +GF W +TLV
Sbjct: 168 QDIGWFDVNETGELNTRLIDDVYKIQEGIGDKAAMLIQAYTTFLSAFVIGFTKGWKLTLV 227
Query: 649 MMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRF 828
++ +P + LS A SK + + T EQ YA AGA+AEE ++IRTV + +G RE+ R+
Sbjct: 228 ILAVSPALGLSAALFSKVLTSFTSKEQAAYAKAGAVAEEVLAAIRTVFAFSGQDREIKRY 287
Query: 829 YNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFF 1008
+ LE + GI K I +GF+ + +Y SYALAFWYGSTLI+++ + G + TV F
Sbjct: 288 HKNLEDAKIMGIKKALSANISMGFTFMVIYLSYALAFWYGSTLILSNE-YTIGSVLTVLF 346
Query: 1009 AVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKD 1188
VL G+ ++G + ++ +F +ARGAA V +I+++P ID YS G D++KG+I FK+
Sbjct: 347 VVLIGAFTMGQSSANIQTFASARGAAHKVYSIIDNNPTIDSYSEAGFKPDSIKGNIEFKN 406
Query: 1189 VHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGV 1368
+HF YP+R D+ +LK +SL +K+G +ALVGSSGCGKST V LLQRFYDP G V +DG
Sbjct: 407 IHFSYPTRPDVQILKNMSLSVKSGQTMALVGSSGCGKSTTVQLLQRFYDPQDGAVFVDGH 466
Query: 1369 DLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRL 1548
D+R +NV LRE IG+VSQEP+LF TI ENI+ G T ++ +A K ANA DFI +L
Sbjct: 467 DIRSLNVRYLREMIGVVSQEPILFATTISENIRYGRLDVTDQEIEQAAKEANAYDFIIKL 526
Query: 1549 PDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQA 1728
PD + T VG++G Q+SGGQKQR+AIARALV+NPKILLLDEATSALD E+E VQ ALD+
Sbjct: 527 PDKFETLVGDRGTQMSGGQKQRVAIARALVRNPKILLLDEATSALDAESETIVQAALDKV 586
Query: 1729 QAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXX 1908
+ GRTTI+VAHRLSTIRN D I F+ G + E G+H +LM K+GI+ +
Sbjct: 587 RLGRTTIVVAHRLSTIRNADVIAGFQDGQVAEVGTHSQLMEKKGIYQRLV--TTQTFQDV 644
Query: 1909 EAGKDIEDTISESAHSHLXXX--------------XXXXXXXXXXXXIHQLAEEVEECK- 2043
E K+ E+ +S S L +E EE +
Sbjct: 645 EEAKEAEEELSVDEKSPLADSLSECTPYRRKTTRGSSMSASEGGKEKTESDKDETEEDEN 704
Query: 2044 APPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQM-QANV 2220
PP S K+ + N + + ++ PVFA+++++I V++ ++ +
Sbjct: 705 VPPVSFLKVLRLNLPEWPYMLVGTVCAIINGAMQPVFAIIFSKIITVFAEKDQELVRQRA 764
Query: 2221 YFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTG 2400
+ MF ++G FV F C G+ GE LT+KLR AFK ++RQD++++D+ ++ G
Sbjct: 765 TLFSLMFAVIGGVSFVTMFLQGFCFGKSGEILTLKLRLGAFKAMMRQDLSWFDNPKNSVG 824
Query: 2401 KLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGG 2577
L TR ATDA V+ R+ + + + ++ I F YGW+ + G
Sbjct: 825 ALTTRLATDAAQVQGATGVRMATLAQNFANLGTSVIISFIYGWELTLLILAVVPAMVLAG 884
Query: 2578 YFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNL 2757
EM++ G + D + LE+AGK++++A+E+IRTV SL R+ +F Y + L P+ +
Sbjct: 885 AVEMKLLTGHAVEDKKELEKAGKISTEAIENIRTVASLTREPKFESLYHKNLEVPYKNST 944
Query: 2758 KHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTT 2937
K AH YGA FAFSQ++I+F YA F G+ + + M V+ V A+ + IG
Sbjct: 945 KKAHVYGATFAFSQAMIYFAYAGCFRFGAWLIEEGRMDVQGVFLVISAVLYGAMAIGEAN 1004
Query: 2938 SFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKP-ITGNISIRNVFFNYPTRKDTKV 3114
SF P+ KA+++AS L L+ ID+LS G GN+ NV FNYP+R + V
Sbjct: 1005 SFAPNYAKAKMSASHLMMLMNLEPAIDNLSQEGETPDRFDGNVHFENVRFNYPSRPNLPV 1064
Query: 3115 LQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQ 3294
LQG L++K G+T+ALVG SGCGKSTI+ LLERFY+ +G +++D N + LNI LR Q
Sbjct: 1065 LQGLDLEVKRGETLALVGSSGCGKSTIIQLLERFYDPREGSVVLDNVNTKQLNIHWLRSQ 1124
Query: 3295 VCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEK 3471
+ IVSQEPTLFDCT+ +NI YG N R T EIV AAK ANIH+FI LP+ YDT G+K
Sbjct: 1125 MGIVSQEPTLFDCTLAQNIAYGDNSRIATMDEIVAAAKAANIHSFIQELPEKYDTQAGDK 1184
Query: 3472 GTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAH 3651
GTQLSGGQKQRIAIARA++R+P +LLLDEATSALDTESEK+VQEALD A +GRTC+++AH
Sbjct: 1185 GTQLSGGQKQRIAIARAILRNPMLLLLDEATSALDTESEKVVQEALDQASKGRTCIIVAH 1244
Query: 3652 RLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
RLSTIQN+D IA++ G +VE+GTH +L+ K +Y TQ
Sbjct: 1245 RLSTIQNADRIAVLQGGVVVEQGTHQQLLAKRGVYHMLVTTQ 1286
>gi|17558664|ref|NP_507487.1| P-GlycoProtein related (pgp-9)
[Caenorhabditis elegans]
gi|7497530|pir||T19982 hypothetical protein C47A10.1 - Caenorhabditis
elegans
gi|3875004|emb|CAB03973.1| Hypothetical protein C47A10.1
[Caenorhabditis elegans]
gi|3879215|emb|CAB07855.1| Hypothetical protein C47A10.1
[Caenorhabditis elegans]
Length = 1294
Score = 992 bits (2565), Expect = 0.0
Identities = 530/1253 (42%), Positives = 767/1253 (60%), Gaps = 19/1253 (1%)
Frame = +1
Query: 94 KLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVD 273
K++ + ++ YT VD L+L G + + G G PL++I++G ++ F+ + +D
Sbjct: 28 KISIFQLYRYTSTVDRLMLAVGIIVSCATGVGLPLMSIIMGNVSQNFVTLGT----IFLD 83
Query: 274 NVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYL 453
+ + EF+ EV++ C+ Y+ LG +F ++Q +CF E+L ++ R+ +
Sbjct: 84 PNSTASEKAAARAEFSHEVIQNCLKYVYLGCGIFAAGFLQASCFMVICEKLSNRFRRQFF 143
Query: 454 KAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSW 633
+++RQ+I W+DK +G L+ +L D+LERVREG GDK L QM A F+ G+ V F Y W
Sbjct: 144 HSVMRQEIAWYDKNTSGTLSNKLFDNLERVREGTGDKVGLAFQMMAQFIGGFAVAFTYDW 203
Query: 634 SMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKR 813
+TL+MM +P +++ G ++K +AT E + YAVAG IAEE +SIRTV + NG +
Sbjct: 204 LLTLIMMSLSPFMMICGLFLAKLLATAATKEAKQYAVAGGIAEEVLTSIRTVIAFNGQEY 263
Query: 814 ELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLI 993
E R+ +ALE G++TGI K +G G+ + +Y+SY LAFW G+ + + + G +
Sbjct: 264 ECKRYEDALEHGKKTGIKKSFLIGAGLASFFVIIYASYCLAFWVGTNFVYSG-RLESGTV 322
Query: 994 FTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGD 1173
TVFF+V+ GS +LG A A+ GTA GAA+++ VI+ P+ID YS EG + G
Sbjct: 323 LTVFFSVMMGSMALGQAGQQFATIGTALGAAASLYEVIDRIPEIDAYSTEGQTPSKISGR 382
Query: 1174 ISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRV 1353
IS V F YP+R D+ +LKG+SL+ + G +ALVGSSGCGKSTI+ LLQRFY+P G++
Sbjct: 383 ISVNKVEFTYPTRADVKILKGVSLDAQPGQTVALVGSSGCGKSTIIQLLQRFYNPDAGQI 442
Query: 1354 LIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAND 1533
LID + + + N+ LR+ +G+VSQEP LF+ +I +NI+ G + + + A K ANA D
Sbjct: 443 LIDDIPIEDFNIKYLRQLVGVVSQEPNLFNTSIEQNIRYGRSDVSDEDIARALKEANAAD 502
Query: 1534 FIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQG 1713
FIK P+G T VG++GVQ+SGGQKQRIAIARALV+NPKILLLDEATSALD E+E VQ
Sbjct: 503 FIKTFPEGLNTLVGDRGVQMSGGQKQRIAIARALVRNPKILLLDEATSALDAESESIVQS 562
Query: 1714 ALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXX 1893
AL+ A GRTTI++AHRLST+RN D+I V KAG ++E G+HE L+ ++G+++++
Sbjct: 563 ALENASRGRTTIVIAHRLSTVRNADKIIVMKAGQVMEVGTHETLIEQKGLYHELVHAQVF 622
Query: 1894 XXXXXE-AGKDIEDTISESAHSHLXXXXXXXXXX-------------XXXXXIHQLAEEV 2031
+ K+ E +S I +L +E+
Sbjct: 623 ADVDDKPKKKEAERRMSRQTSQRKGSVNFKTQESQVDEKPGAPPAPEAAEKEIKRLKKEL 682
Query: 2032 EECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLP-ADQM 2208
EE A ++FKI ++ + + +V P F+L +++I NV+S P DQM
Sbjct: 683 EEEGAVKANLFKILRYARPEWIYIFFAIIAALIQGAVMPAFSLFFSQIINVFSNPDRDQM 742
Query: 2209 QANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLR 2388
+ + +FW MF+++ + G E LTM++R + ++N+LRQD ++D +
Sbjct: 743 KKDGHFWALMFLVLAAVQGTSMLFQCSLFGVAAERLTMRIRSKVYRNVLRQDATYFDMPK 802
Query: 2389 HGTGKLCTRFATDAPNVRYVFT-RLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXX 2565
H G++ TR ATDAPN++ RL + +I ++ G LGI FYYGWQ
Sbjct: 803 HSPGRITTRLATDAPNIKSAIDYRLGSIFNAIASVGGGLGIAFYYGWQMAFLVMAIFPFM 862
Query: 2566 XMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPF 2745
+G M+ G D + +E AGK A +A+E+IRTV +L Q + + +C +L P
Sbjct: 863 AVGQALMMKYHGGSATSDAKEMENAGKTAMEAIENIRTVQALTLQTKLYNIFCSHLDAPH 922
Query: 2746 NTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLG--SIFVNQQAMQPIDVYRVFFAISFCGQ 2919
N+ A G + F+ S+ FF YAAAF G IF M+P +V RV FAISF
Sbjct: 923 GGNISKAIIRGLTYGFANSIQFFTYAAAFRFGLFLIFDKNVLMEPENVLRVLFAISFSFG 982
Query: 2920 MIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPTR 3099
IG S+ P+ +KA AA L+F ++E ID ++ SG ++G + + VFF YP R
Sbjct: 983 TIGFAASYFPEYIKATFAAGLIFNMLEEEPRIDGMTSSGTYPQLSGEVKLNKVFFRYPER 1042
Query: 3100 KDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNIS 3279
+LQG + +K G+T+ALVG SGCGKST++ LLER Y+ +G + +D +++R +N
Sbjct: 1043 PAVPILQGLNVHVKPGQTLALVGPSGCGKSTVISLLERLYDPLEGAVTVDNNDLRQMNPK 1102
Query: 3280 SLREQVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDT 3456
LR+ + +VSQEP LFD +I ENI YG T+++I A ANIH FI LPDGY+T
Sbjct: 1103 HLRKHIALVSQEPILFDTSIRENIVYGLQPGEYTHEQIETACSKANIHKFIDELPDGYET 1162
Query: 3457 HVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTC 3636
VGEKGTQLSGGQKQRIAIARAL+R+P +LLLDEATSALDTESEK VQ ALDAA + RTC
Sbjct: 1163 RVGEKGTQLSGGQKQRIAIARALIRNPKILLLDEATSALDTESEKQVQVALDAAAKDRTC 1222
Query: 3637 LVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRIVESQ 3795
+V+AHRLSTI N+ I +V G++VE+GTH+ELI K Y F TQ+ +Q
Sbjct: 1223 IVVAHRLSTIVNAGCIMVVKNGQVVEQGTHNELIAKRGAY--FALTQKQSSNQ 1273
Score = 375 bits (962), Expect = e-102
Identities = 221/601 (36%), Positives = 326/601 (53%), Gaps = 5/601 (0%)
Frame = +1
Query: 91 VKLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGV 270
VK + I Y + + + + +AA+I GA P ++ + VF
Sbjct: 688 VKANLFKILRYARP-EWIYIFFAIIAALIQGAVMPAFSLFFSQIINVFS----------- 735
Query: 271 DNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNY 450
NP+ D+ + + + +LVL + + Q + F AERL ++R
Sbjct: 736 ---NPDR------DQMKKDGHFWALMFLVLAAVQGTSMLFQCSLFGVAAERLTMRIRSKV 786
Query: 451 LKAILRQQIQWFD--KQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFF 624
+ +LRQ +FD K G +T RL D ++ + + + A+ G G+ F+
Sbjct: 787 YRNVLRQDATYFDMPKHSPGRITTRLATDAPNIKSAIDYRLGSIFNAIASVGGGLGIAFY 846
Query: 625 YSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNG 804
Y W M ++M P + + A M K + + AG A E +IRTV +L
Sbjct: 847 YGWQMAFLVMAIFPFMAVGQALMMKYHGGSATSDAKEMENAGKTAMEAIENIRTVQALTL 906
Query: 805 HKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIIN-DPTFD 981
+ + F + L+ I K G+ GF+N + +YA AF +G LI + + +
Sbjct: 907 QTKLYNIFCSHLDAPHGGNISKAIIRGLTYGFANSIQFFTYAAAFRFGLFLIFDKNVLME 966
Query: 982 RGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDN 1161
+ V FA+ ++G A + + A AA + ++ P+ID + G
Sbjct: 967 PENVLRVLFAISFSFGTIGFAASYFPEYIKATFAAGLIFNMLEEEPRIDGMTSSGTY-PQ 1025
Query: 1162 MKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPT 1341
+ G++ V FRYP R + +L+G+++ +K G +ALVG SGCGKST+++LL+R YDP
Sbjct: 1026 LSGEVKLNKVFFRYPERPAVPILQGLNVHVKPGQTLALVGPSGCGKSTVISLLERLYDPL 1085
Query: 1342 KGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHA--THDQVVEACK 1515
+G V +D DLR++N LR+ I +VSQEP+LFD +I ENI G + TH+Q+ AC
Sbjct: 1086 EGAVTVDNNDLRQMNPKHLRKHIALVSQEPILFDTSIRENIVYGLQPGEYTHEQIETACS 1145
Query: 1516 MANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEA 1695
AN + FI LPDGY TRVGEKG QLSGGQKQRIAIARAL++NPKILLLDEATSALDTE+
Sbjct: 1146 KANIHKFIDELPDGYETRVGEKGTQLSGGQKQRIAIARALIRNPKILLLDEATSALDTES 1205
Query: 1696 EREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM 1875
E++VQ ALD A RT I+VAHRLSTI N I V K G +VE G+H EL++K+G ++ +
Sbjct: 1206 EKQVQVALDAAAKDRTCIVVAHRLSTIVNAGCIMVVKNGQVVEQGTHNELIAKRGAYFAL 1265
Query: 1876 T 1878
T
Sbjct: 1266 T 1266
>gi|39587899|emb|CAE67917.1| Hypothetical protein CBG13514
[Caenorhabditis briggsae]
Length = 1319
Score = 988 bits (2553), Expect = 0.0
Identities = 532/1261 (42%), Positives = 771/1261 (60%), Gaps = 33/1261 (2%)
Frame = +1
Query: 94 KLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVD 273
K+T ++ YT + ++L+ GT+ A+I GAG PL++I+ G ++ F+ N V+
Sbjct: 59 KVTIPQLYRYTTMTEKIMLLVGTIVAIITGAGLPLMSILQGQVSQAFI---NEQIVINTG 115
Query: 274 N--VNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQN 447
N + P G D FN +V++ Y + + M+ + + C+ AE++ ++LR+
Sbjct: 116 NHTIPPNGRNYTDSD-FNHDVMQVVWLYAGMTIGMWAAGQITVTCYLYVAEQMNNRLRRE 174
Query: 448 YLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFY 627
++KAILRQ I WFD +G L +L D+LERV+EG GDK + Q + F+ G+ V F +
Sbjct: 175 FVKAILRQDISWFDTNHSGTLATKLFDNLERVKEGTGDKIGMAFQYMSQFITGFIVAFTH 234
Query: 628 SWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGH 807
SW +TLVM+ P+ L G ++KSM+T E YA AG + EET SSIRTV SLNG
Sbjct: 235 SWKLTLVMLAVTPIQALCGFLIAKSMSTFAIRETVRYAKAGKVVEETISSIRTVVSLNGL 294
Query: 808 KRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRG 987
+ EL+R+ A+E +++G++K ++GI G + S+ALAF+ G + +D + G
Sbjct: 295 RHELERYSTAVEEAKKSGVLKGLFLGISFGAMQATNFFSFALAFYIGVGWV-HDGSLAPG 353
Query: 988 LIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMK 1167
+ T F +V+ GS +LG A P LA GTA+GAAS++ V++ P ID S G +K
Sbjct: 354 DMLTTFSSVMMGSMALGLAGPQLAVLGTAQGAASSIYEVLDRKPVIDSSSSAGRKDMKIK 413
Query: 1168 GDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKG 1347
GDI+ ++VHF YPSR+D+ +L+G++L + AG +ALVGSSGCGKSTI++LL R+YD KG
Sbjct: 414 GDITVENVHFTYPSRQDVPILRGMNLRVNAGQTVALVGSSGCGKSTIISLLLRYYDVLKG 473
Query: 1348 RVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANA 1527
+ IDGVD+R++N+ LR + +VSQEP LF+ TI ENI++G E T ++++ ACKMANA
Sbjct: 474 NITIDGVDVRDINLEFLRTNVAVVSQEPALFNCTIEENIRLGREDITREEMIAACKMANA 533
Query: 1528 NDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREV 1707
FIK LP GY T VG++G QLSGGQKQRIAIARALV+NPKILLLDEATSALD E+E V
Sbjct: 534 EKFIKTLPAGYNTLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDAESEGIV 593
Query: 1708 QGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM-TXX 1884
Q ALD+A GRTTII+AHRLSTIRN D I K G +VE G H LM+++G++YD+ T
Sbjct: 594 QQALDKAAKGRTTIIIAHRLSTIRNADLIISCKNGQVVEVGDHRTLMAQEGLYYDLVTAQ 653
Query: 1885 XXXXXXXXEAG-----------------------KDIEDTISESAHSHLXXXX-----XX 1980
AG +++D ++ S +
Sbjct: 654 TFTDAVDASAGGKFSRENSIARQTSEHEGIFRQASELDDVLNRVRSSTMGSITNGPVIEE 713
Query: 1981 XXXXXXXXXIHQLAEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFAL 2160
+ +L EE+EE A T++F+I + P +++
Sbjct: 714 KEQRIGKDALTRLKEELEENNAQRTNLFEILYHAKPHALSVAIGITAAIVGGFIYPTYSV 773
Query: 2161 VYAEIFNVYSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEA 2340
+ NV+S D + + +FW MF+++ + F +G ESLTM LR +
Sbjct: 774 FFTSFINVFSGNPDDILSQGHFWALMFLVLAAAQGICSFLMTFFMGIASESLTMDLRNKL 833
Query: 2341 FKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVFT-RLPVVLASIVTICGALGIGFY 2517
F+N+L Q I F+D ++ +GK+CTR ATD PN+R R V+ ++V++ +G+ FY
Sbjct: 834 FRNVLSQHIGFFDSPQNASGKICTRLATDVPNLRTAIDFRFSTVITTLVSMIAGIGLAFY 893
Query: 2518 YGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNR 2697
YGWQ G Y + G ++ ++GK+A +A+E++RTV +L R
Sbjct: 894 YGWQMALLIVAILPIVGFGQYLRGRRFTGNNVKSASEFADSGKIAIEAIENVRTVQALAR 953
Query: 2698 QEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPI 2877
++ F++ +C L P +K A G + + S+++ + A+ +G + + M P+
Sbjct: 954 EDTFYYKFCSKLDVPHKEAIKEAFIQGLSYGCACSVLYLLNTCAYRMGLALILHRTMTPM 1013
Query: 2878 DVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITG 3057
V RV +AI+ +G TS+ P+ KA A ++F +++ + IDSL+ SG K ++G
Sbjct: 1014 RVLRVMYAITISTSTLGFATSYFPEYAKATFAGGIIFGMLKQKSEIDSLTLSGEKKKLSG 1073
Query: 3058 NISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGM 3237
+ +NV F YP R ++L+G + + G+T+ALVG SGCGKST++ LLERFY+ G
Sbjct: 1074 KVIFKNVRFAYPERPQIEILKGLSFSVDPGQTLALVGPSGCGKSTVVALLERFYDTLAGE 1133
Query: 3238 IMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMAN 3414
+ IDG I+ LN + R Q+ IVSQEPTLFDC+I ENI YG + VT + EAAK+AN
Sbjct: 1134 VFIDGSEIKTLNPENTRSQIAIVSQEPTLFDCSIAENIVYGLDPTTVTMSRVEEAAKLAN 1193
Query: 3415 IHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKI 3594
IHNFI LP+GY+T VG++GTQLSGGQKQRIAIARALVR+P +LLLDEATSALDTESEKI
Sbjct: 1194 IHNFISELPEGYETRVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEKI 1253
Query: 3595 VQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCET 3774
VQEALD A++GRTC+VIAHRL+TI N+D IA+V+ G I+E+GTH L+ + Y K +
Sbjct: 1254 VQEALDRAREGRTCIVIAHRLNTIMNADCIAVVNNGTIIEQGTHSVLMSQQGAYYKLTQK 1313
Query: 3775 Q 3777
Q
Sbjct: 1314 Q 1314
Score = 333 bits (854), Expect = 2e-89
Identities = 207/533 (38%), Positives = 300/533 (55%), Gaps = 2/533 (0%)
Frame = +1
Query: 2200 DQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYD 2379
D MQ V+ + GM + M + G T C E + +LR E K +LRQDI+++D
Sbjct: 134 DVMQV-VWLYAGMTIGM---WAAGQIT-VTCYLYVAEQMNNRLRREFVKAILRQDISWFD 188
Query: 2380 DLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXX 2556
GT L T+ + V+ ++ + + + F + W+
Sbjct: 189 TNHSGT--LATKLFDNLERVKEGTGDKIGMAFQYMSQFITGFIVAFTHSWKLTLVMLAVT 246
Query: 2557 XXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLR 2736
+ G+ + IR+T +AGKV + + IRTV SLN Y +
Sbjct: 247 PIQALCGFLIAKSMSTFAIRETVRYAKAGKVVEETISSIRTVVSLNGLRHELERYSTAVE 306
Query: 2737 EPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCG 2916
E + + G F Q+ FF +A AFY+G +V+ ++ P D+ F ++
Sbjct: 307 EAKKSGVLKGLFLGISFGAMQATNFFSFALAFYIGVGWVHDGSLAPGDMLTTFSSVMMGS 366
Query: 2917 QMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVK-PITGNISIRNVFFNYP 3093
+G + + A+ AAS ++ +++ IDS S +G I G+I++ NV F YP
Sbjct: 367 MALGLAGPQLAVLGTAQGAASSIYEVLDRKPVIDSSSSAGRKDMKIKGDITVENVHFTYP 426
Query: 3094 TRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLN 3273
+R+D +L+G L + AG+TVALVG SGCGKSTI+ LL R+Y+ KG I IDG ++R++N
Sbjct: 427 SRQDVPILRGMNLRVNAGQTVALVGSSGCGKSTIISLLLRYYDVLKGNITIDGVDVRDIN 486
Query: 3274 ISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYD 3453
+ LR V +VSQEP LF+CTI ENI G ++T +E++ A KMAN FI LP GY+
Sbjct: 487 LEFLRTNVAVVSQEPALFNCTIEENIRLG-REDITREEMIAACKMANAEKFIKTLPAGYN 545
Query: 3454 THVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRT 3633
T VG++GTQLSGGQKQRIAIARALVR+P +LLLDEATSALD ESE IVQ+ALD A +GRT
Sbjct: 546 TLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDAESEGIVQQALDKAAKGRT 605
Query: 3634 CLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRIVES 3792
++IAHRLSTI+N+D+I G++VE G H L+ + +Y Q ++
Sbjct: 606 TIIIAHRLSTIRNADLIISCKNGQVVEVGDHRTLMAQEGLYYDLVTAQTFTDA 658
>gi|39585393|emb|CAE61715.1| Hypothetical protein CBG05664
[Caenorhabditis briggsae]
Length = 1294
Score = 987 bits (2552), Expect = 0.0
Identities = 527/1249 (42%), Positives = 764/1249 (60%), Gaps = 19/1249 (1%)
Frame = +1
Query: 94 KLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVD 273
K++ + +F YT +D ++LI G + + G G PL++I++G ++ F+ + ++
Sbjct: 29 KISIFQLFRYTSTMDRIMLIVGILVSCATGLGLPLMSIIMGNVSQNFVEIGT----ILMN 84
Query: 274 NVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYL 453
+ +P ++ + D+F+ +V++ C+ Y+ LG +F +Q +CF E L ++ R+ +
Sbjct: 85 STDP-AVIKKAKDDFSHDVIQNCLQYVYLGAGIFAAGMIQASCFLIICENLSNRFRREFF 143
Query: 454 KAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSW 633
+++R +I W+DK +G L+ +L D+LERVREG GDK L QM A FL G+ V F Y W
Sbjct: 144 YSVMRHEIAWYDKNTSGTLSNKLFDNLERVREGTGDKVGLAFQMMAQFLGGFAVAFSYDW 203
Query: 634 SMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKR 813
+TL+MM +P +++ G ++K +AT E + YAVAG IAEE +SIRTV + NG +
Sbjct: 204 LLTLIMMSLSPFMMICGLFLAKLLATAATKEAKQYAVAGGIAEEVLTSIRTVIAFNGQEY 263
Query: 814 ELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLI 993
E R+ AL GR+TGI K +G G+ + +Y+SY LAFW G+ + N D G +
Sbjct: 264 ECKRYEEALSHGRKTGIKKSFLIGAGLASFFVIIYASYCLAFWVGTNFVYNG-RLDSGTV 322
Query: 994 FTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGD 1173
TVFF+V+ GS +LG A A+ GTA GAA+++ VI+ P+ID YS +G+ + + G
Sbjct: 323 LTVFFSVMMGSMALGQAGQQFATIGTALGAAASLYEVIDRTPEIDAYSTKGVTPEKISGR 382
Query: 1174 ISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRV 1353
I +++ F YP+R D+ +LK +SLE + G IALVGSSGCGKSTI+ LLQRFY+P G++
Sbjct: 383 IKIQNIEFTYPTRPDVQILKDVSLEAQPGQTIALVGSSGCGKSTIIQLLQRFYNPDAGKI 442
Query: 1354 LIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAND 1533
ID + + + N+ LR+ +G+VSQEP LF+ +I +NI+ G D + A K ANA D
Sbjct: 443 YIDDIAIEDFNIKYLRQLVGVVSQEPNLFNTSIEQNIRYGRADVDSDAINRALKEANALD 502
Query: 1534 FIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQG 1713
FIK P+G T VG++GVQ+SGGQKQRIAIARALV+NPKILLLDEATSALD E+E VQ
Sbjct: 503 FIKTFPEGLNTLVGDRGVQMSGGQKQRIAIARALVRNPKILLLDEATSALDAESESVVQA 562
Query: 1714 ALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXX 1893
ALD A GRTTI++AHRLST+RN D+I V KAG ++E G+H+ L+ ++G+++++
Sbjct: 563 ALDNASRGRTTIVIAHRLSTVRNADKIIVMKAGKVMEIGTHDTLIEQKGLYHELVHAQVF 622
Query: 1894 XXXXXE--AGKDIEDTISESAHSHLXXXXXXXXXXX------------XXXXIHQLAEEV 2031
+ A K+ E +S + I +L +E+
Sbjct: 623 ADVDEKPRAKKEAERRLSRQTSARKGSLIKTQESQAEEKSGPPPAPEPAEKEIKRLRKEL 682
Query: 2032 EECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLP-ADQM 2208
EE A ++FKI K+ + + +V P F+L +++I NV+S P +QM
Sbjct: 683 EEEGAVKANLFKILKYARPEWMYIFFAIIAALIQGAVMPAFSLFFSQIINVFSNPDREQM 742
Query: 2209 QANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLR 2388
+ + +FW MF+++ G E LTM++R + ++N+LRQD ++D +
Sbjct: 743 KKDGHFWALMFLVLAAIQGTSMLFQCAFFGVAAEGLTMRVRSKVYRNVLRQDATYFDMPK 802
Query: 2389 HGTGKLCTRFATDAPNVRYVFT-RLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXX 2565
H G++ TR ATDAPN++ RL V +I ++ G LGI FYYGWQ
Sbjct: 803 HSPGRITTRLATDAPNIKSAIDYRLGSVFNAIASVGGGLGIAFYYGWQMALLVMAIFPFM 862
Query: 2566 XMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPF 2745
+G ++ G D + +E +GK A +A+E+IRTV +L Q + + +C +L P
Sbjct: 863 AVGQALVIKYHGGSATADAKEMENSGKTAMEAIENIRTVQALTLQTKLYNIFCSHLDSPH 922
Query: 2746 NTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLG--SIFVNQQAMQPIDVYRVFFAISFCGQ 2919
+ N+ A G + F+ S+ FF YAAAF G IF M P V +V FAISF
Sbjct: 923 SGNVSKAIIRGLTYGFANSIQFFTYAAAFRFGLFLIFNQNVLMSPEHVLKVLFAISFSFG 982
Query: 2920 MIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPTR 3099
IG S+ P+ +KA AA L+F ++E ID ++++G + ++G + + VFF YP R
Sbjct: 983 TIGFAASYFPEYIKATFAAGLIFNMLEEEPRIDGMTNAGTLPALSGEVKLNKVFFRYPER 1042
Query: 3100 KDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNIS 3279
+LQG + +K G+T+ALVG SGCGKST++ LLER Y+ +G + ID +N+R +N
Sbjct: 1043 PAVPILQGLDVHVKPGQTLALVGPSGCGKSTVISLLERLYDPLEGAVTIDNNNLRQMNPK 1102
Query: 3280 SLREQVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDT 3456
LR+ + +VSQEP LFD +I ENI YG T + I A + ANIH FI LPDGY T
Sbjct: 1103 HLRKHIALVSQEPILFDTSIRENIIYGLQPGEYTEEAIAVACEKANIHKFISELPDGYQT 1162
Query: 3457 HVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTC 3636
VGEKGTQLSGGQKQRIAIARAL+R+P +LLLDEATSALDTESEK VQ ALDAA + RTC
Sbjct: 1163 RVGEKGTQLSGGQKQRIAIARALIRNPKILLLDEATSALDTESEKQVQIALDAAAKDRTC 1222
Query: 3637 LVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRI 3783
+V+AHRLSTI N+ I +V GK+VE+GTH EL+ K Y + Q I
Sbjct: 1223 IVVAHRLSTIVNAGCIMVVKNGKVVEQGTHLELMAKRGAYFALTQKQSI 1271
Score = 365 bits (936), Expect = 6e-99
Identities = 219/601 (36%), Positives = 323/601 (53%), Gaps = 5/601 (0%)
Frame = +1
Query: 91 VKLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGV 270
VK + I Y + + + + +AA+I GA P ++ + VF
Sbjct: 688 VKANLFKILKYARP-EWMYIFFAIIAALIQGAVMPAFSLFFSQIINVFS----------- 735
Query: 271 DNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNY 450
NP+ ++ + + + +LVL + + Q A F AE L ++R
Sbjct: 736 ---NPDR------EQMKKDGHFWALMFLVLAAIQGTSMLFQCAFFGVAAEGLTMRVRSKV 786
Query: 451 LKAILRQQIQWFD--KQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFF 624
+ +LRQ +FD K G +T RL D ++ + + + A+ G G+ F+
Sbjct: 787 YRNVLRQDATYFDMPKHSPGRITTRLATDAPNIKSAIDYRLGSVFNAIASVGGGLGIAFY 846
Query: 625 YSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNG 804
Y W M L++M P + + A + K + + +G A E +IRTV +L
Sbjct: 847 YGWQMALLVMAIFPFMAVGQALVIKYHGGSATADAKEMENSGKTAMEAIENIRTVQALTL 906
Query: 805 HKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTF-D 981
+ + F + L+ + K G+ GF+N + +YA AF +G LI N
Sbjct: 907 QTKLYNIFCSHLDSPHSGNVSKAIIRGLTYGFANSIQFFTYAAAFRFGLFLIFNQNVLMS 966
Query: 982 RGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDN 1161
+ V FA+ ++G A + + A AA + ++ P+ID + G L
Sbjct: 967 PEHVLKVLFAISFSFGTIGFAASYFPEYIKATFAAGLIFNMLEEEPRIDGMTNAGTL-PA 1025
Query: 1162 MKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPT 1341
+ G++ V FRYP R + +L+G+ + +K G +ALVG SGCGKST+++LL+R YDP
Sbjct: 1026 LSGEVKLNKVFFRYPERPAVPILQGLDVHVKPGQTLALVGPSGCGKSTVISLLERLYDPL 1085
Query: 1342 KGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHA--THDQVVEACK 1515
+G V ID +LR++N LR+ I +VSQEP+LFD +I ENI G + T + + AC+
Sbjct: 1086 EGAVTIDNNNLRQMNPKHLRKHIALVSQEPILFDTSIRENIIYGLQPGEYTEEAIAVACE 1145
Query: 1516 MANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEA 1695
AN + FI LPDGY TRVGEKG QLSGGQKQRIAIARAL++NPKILLLDEATSALDTE+
Sbjct: 1146 KANIHKFISELPDGYQTRVGEKGTQLSGGQKQRIAIARALIRNPKILLLDEATSALDTES 1205
Query: 1696 EREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM 1875
E++VQ ALD A RT I+VAHRLSTI N I V K G +VE G+H ELM+K+G ++ +
Sbjct: 1206 EKQVQIALDAAAKDRTCIVVAHRLSTIVNAGCIMVVKNGKVVEQGTHLELMAKRGAYFAL 1265
Query: 1876 T 1878
T
Sbjct: 1266 T 1266
>gi|50732589|ref|XP_418707.1| PREDICTED: similar to ATP-binding
cassette, sub-family B (MDR/TAP), member 1A; multiple
drug resistant 1a [Gallus gallus]
Length = 1734
Score = 987 bits (2552), Expect = 0.0
Identities = 543/1251 (43%), Positives = 754/1251 (59%), Gaps = 36/1251 (2%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVF-LRAQNSDFVVGVDNVNPE 288
+F Y VD+LL++ G +AA +G G PL+ I+ G MT F L NS G +VN
Sbjct: 114 LFRYADWVDILLMVVGLIAAAANGTGLPLMIIIFGDMTNAFVLSGVNSSTSEGA-SVNNS 172
Query: 289 GLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILR 468
P + +++ K+ YY+ +G + S +Q+ F A R ++R+ + A+L
Sbjct: 173 SCQPAPGVDIEADMTKFAYYYVGIGFAVLILSTIQVWTFLIAATRQTSRIRRKFFFAVLH 232
Query: 469 QQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLV 648
Q++ WFD Q G L RLTDD+ + EG+GDK + VQ F+ FLAG +GF + W +TLV
Sbjct: 233 QEMAWFDSTQIGTLNTRLTDDINTIHEGIGDKICIFVQFFSTFLAGITIGFAHGWKLTLV 292
Query: 649 MMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRF 828
++ +PL+ S A S +A+ T E YA AGA+AEE ++IRTV + NG ++ L ++
Sbjct: 293 ILSVSPLLAASAAVWSTLLASLTAKELSAYAKAGAVAEEVLTAIRTVVAFNGQQKALAKY 352
Query: 829 YNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDP-TFDRGLIFTVF 1005
LE R G+ K +G S ++ SYALAFWYG+ L + +P +D G + VF
Sbjct: 353 DTNLEAARHVGVKKSITTNTSLGVSQFLIFGSYALAFWYGTKLTVEEPENYDIGRVLIVF 412
Query: 1006 FAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFK 1185
F+VL G+ SLG A P+L S ARGAA V ++IN ID S EG D +KG+I F+
Sbjct: 413 FSVLIGAFSLGQAAPNLESVANARGAAYEVYQIINKKRLIDSSSKEGYKPDKLKGEIEFR 472
Query: 1186 DVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDG 1365
++HF YPSR DI +LKG++L+++ G IALVG+SGCGKST V LLQRFYDP +G V +DG
Sbjct: 473 NIHFSYPSRPDITILKGLNLKVQTGKTIALVGASGCGKSTTVQLLQRFYDPDQGEVTLDG 532
Query: 1366 VDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKR 1545
D+R +NV LRE IGIVSQEPVLF TI ENI+ G E + ++ +A K ANA DFI R
Sbjct: 533 RDIRTLNVKWLRENIGIVSQEPVLFATTIAENIRYGREDISDAEIEQAAKEANAFDFISR 592
Query: 1546 LPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQ 1725
LPD + T VGE+G QLSGGQKQRIAIARAL +NPKILLLDEATSALDT++E VQ ALD+
Sbjct: 593 LPDKFNTMVGERGAQLSGGQKQRIAIARALARNPKILLLDEATSALDTQSESVVQAALDK 652
Query: 1726 AQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXX 1905
A+ GRTTI++AHRLSTIR D I F+ G +VE G+H ELM ++G++Y +
Sbjct: 653 ARTGRTTIVIAHRLSTIRTADTIAAFEKGIVVEQGTHSELMLQKGVYYSLVMQQSGSNNV 712
Query: 1906 XEAGKDIEDTISESAH------------------------------SHLXXXXXXXXXXX 1995
+ G ED +E+
Sbjct: 713 QDDGTSEEDEETEAEEYEENDKSSSVEKLNLKDHFEEPVITGRGSIRRRSSRYKSKRSSS 772
Query: 1996 XXXXIHQLAEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEI 2175
+ +E+EE P +I N + + V P FA+++ +I
Sbjct: 773 KKKSSKKKKKELEEENLPAVPYTRILALNKPEWLYVLLGVIAAAVSGGVHPAFAVIFGKI 832
Query: 2176 FNVY-SLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNL 2352
+ ++ N MF+L+G+ + G+ GE LTM+LR +FK L
Sbjct: 833 IGAFQERDPERRNKNTLVLSLMFLLLGVITLATYIIQGFMFGKSGEILTMRLRSLSFKAL 892
Query: 2353 LRQDIAFYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQ 2529
L+Q+I +YDD ++ G L TR ATDA V+ +RL ++ ++ T+ A+ I F YGWQ
Sbjct: 893 LQQEIGWYDDQKNAVGVLLTRLATDASQVKGATGSRLGLMTMTVFTLLTAIIIAFVYGWQ 952
Query: 2530 XXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQF 2709
+ G +D + LEEAG+V++++VE+IRTV SL R+E F
Sbjct: 953 LTLLILACIPFVIAANAANVSSVSGHAAKDQKALEEAGRVSTESVENIRTVASLTREEAF 1012
Query: 2710 HFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYR 2889
+ Y L P+ +LK A YG + +QS +F+ AA F G+ + + +V+
Sbjct: 1013 YEKYINSLNGPYRDSLKKAPLYGFTYGIAQSANYFVNAAVFRFGAWLIARCLTNFENVFI 1072
Query: 2890 VFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNIS 3066
VF ++ F +G + S PD KA+++A +F+L++ IDS S+ G + GNI
Sbjct: 1073 VFSSVIFAAMNVGQSASLAPDYGKAKVSAQRIFHLLDRKPQIDSYSEEGEKLSNFEGNIE 1132
Query: 3067 IRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMI 3246
RN+ F YPTR + +VLQG + + G+T+ALVG SGCGKST + LLERFY+ +G ++
Sbjct: 1133 FRNIHFVYPTRPEVQVLQGLNVKVNKGQTLALVGSSGCGKSTSIQLLERFYDPVEGQVLA 1192
Query: 3247 DGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYG-TNRNVTYQEIVEAAKMANIHN 3423
DG + ++L++ LR ++ +VSQEP LFDC+I ENI YG NR V+ +EI EAAK ANIH
Sbjct: 1193 DGFDTKSLHLQWLRSRLGLVSQEPILFDCSIAENIQYGDNNRLVSQEEIEEAAKAANIHA 1252
Query: 3424 FILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQE 3603
FI LP+ Y+T VGEKGTQLSGGQKQRIAIARALVR+P+VLLLDEATSALDTESEKIVQ+
Sbjct: 1253 FIDKLPEKYNTRVGEKGTQLSGGQKQRIAIARALVRNPAVLLLDEATSALDTESEKIVQK 1312
Query: 3604 ALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIY 3756
ALD A+QGRTC+VIAHRL+TIQN+D+IA++ G++VE+GTH +L+ K Y
Sbjct: 1313 ALDNARQGRTCIVIAHRLTTIQNADIIAVIQNGRVVEQGTHSQLLAKEGHY 1363
Score = 397 bits (1020), Expect = e-108
Identities = 222/581 (38%), Positives = 341/581 (58%), Gaps = 5/581 (0%)
Frame = +1
Query: 142 LLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFN 321
L ++ G +AA + G P A++ G + F Q D PE N
Sbjct: 806 LYVLLGVIAAAVSGGVHPAFAVIFGKIIGAF---QERD---------PE--------RRN 845
Query: 322 SEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQT 501
+ + +L+LGV+ T +Q F E L +LR KA+L+Q+I W+D Q+
Sbjct: 846 KNTLVLSLMFLLLGVITLATYIIQGFMFGKSGEILTMRLRSLSFKALLQQEIGWYDDQKN 905
Query: 502 --GNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIV 675
G L RL D +V+ G + L+ L + F Y W +TL+++ P ++
Sbjct: 906 AVGVLLTRLATDASQVKGATGSRLGLMTMTVFTLLTAIIIAFVYGWQLTLLILACIPFVI 965
Query: 676 LSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQ 855
+ A S++ +Q+ AG ++ E+ +IRTV SL + +++ N+L +
Sbjct: 966 AANAANVSSVSGHAAKDQKALEEAGRVSTESVENIRTVASLTREEAFYEKYINSLNGPYR 1025
Query: 856 TGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPT-FDRGLIFTVFFAVLSGSTS 1032
+ K G G + Y A F +G+ LI T F+ +F VF +V+ + +
Sbjct: 1026 DSLKKAPLYGFTYGIAQSANYFVNAAVFRFGAWLIARCLTNFEN--VFIVFSSVIFAAMN 1083
Query: 1033 LGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSR 1212
+G + +G A+ +A + +++ P+ID YS EG + N +G+I F+++HF YP+R
Sbjct: 1084 VGQSASLAPDYGKAKVSAQRIFHLLDRKPQIDSYSEEGEKLSNFEGNIEFRNIHFVYPTR 1143
Query: 1213 KDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVH 1392
++ VL+G+++++ G +ALVGSSGCGKST + LL+RFYDP +G+VL DG D + +++
Sbjct: 1144 PEVQVLQGLNVKVNKGQTLALVGSSGCGKSTSIQLLERFYDPVEGQVLADGFDTKSLHLQ 1203
Query: 1393 SLREQIGIVSQEPVLFDGTIYENIKMG--NEHATHDQVVEACKMANANDFIKRLPDGYGT 1566
LR ++G+VSQEP+LFD +I ENI+ G N + +++ EA K AN + FI +LP+ Y T
Sbjct: 1204 WLRSRLGLVSQEPILFDCSIAENIQYGDNNRLVSQEEIEEAAKAANIHAFIDKLPEKYNT 1263
Query: 1567 RVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTT 1746
RVGEKG QLSGGQKQRIAIARALV+NP +LLLDEATSALDTE+E+ VQ ALD A+ GRT
Sbjct: 1264 RVGEKGTQLSGGQKQRIAIARALVRNPAVLLLDEATSALDTESEKIVQKALDNARQGRTC 1323
Query: 1747 IIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFY 1869
I++AHRL+TI+N D I V + G +VE G+H +L++K+G +Y
Sbjct: 1324 IVIAHRLTTIQNADIIAVIQNGRVVEQGTHSQLLAKEGHYY 1364
>gi|9961252|ref|NP_061338.1| ATP-binding cassette, subfamily B, member
4 isoform C; P glycoprotein 3/multiple drug resistance 3;
P-glycoprotein-3/multiple drug resistance-3; multiple
drug resistance 3 [Homo sapiens]
Length = 1232
Score = 977 bits (2526), Expect = 0.0
Identities = 552/1241 (44%), Positives = 750/1241 (59%), Gaps = 19/1241 (1%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFL-RAQNSDFVVG--VDNVN 282
+F Y+ D L + GT+ A+ HG+G PL+ IV G MT F+ A N F V + +N
Sbjct: 45 LFRYSDWQDKLFMSLGTIMAIAHGSGLPLMMIVFGEMTDKFVDTAGNFSFPVNFSLSLLN 104
Query: 283 PEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAI 462
P ++ E+ +Y YY LG + +Y+Q++ + A R + K+RQ + AI
Sbjct: 105 PGKIL-------EEEMTRYAYYYSGLGAGVLVAAYIQVSFWTLAAGRQIRKIRQKFFHAI 157
Query: 463 LRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMT 642
LRQ+I WFD T L RLTDD+ ++ EG+GDK + Q A F AG+ VGF W +T
Sbjct: 158 LRQEIGWFDINDTTELNTRLTDDISKISEGIGDKVGMFFQAVATFFAGFIVGFIRGWKLT 217
Query: 643 LVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELD 822
LV+M +P++ LS A +K ++ + E YA AGA+AEE +IRTV + G +EL+
Sbjct: 218 LVIMAISPILGLSAAVWAKILSAFSDKELAAYAKAGAVAEEALGAIRTVIAFGGQNKELE 277
Query: 823 RFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTV 1002
R+ LE ++ GI K I +G + L +Y+SYALAFWYGSTL+I+ + G TV
Sbjct: 278 RYQKHLENAKEIGIKKAISANISMGIAFLLIYASYALAFWYGSTLVISKE-YTIGNAMTV 336
Query: 1003 FFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISF 1182
FF++L G+ S+G A P + +F ARGAA + +I+++PKID +S G D++KG++ F
Sbjct: 337 FFSILIGAFSVGQAAPCIDAFANARGAAYVIFDIIDNNPKIDSFSERGHKPDSIKGNLEF 396
Query: 1183 KDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLID 1362
DVHF YPSR ++ +LKG++L++++G +ALVGSSGCGKST V L+QR YDP +G + ID
Sbjct: 397 NDVHFSYPSRANVKILKGLNLKVQSGQTVALVGSSGCGKSTTVQLIQRLYDPDEGTINID 456
Query: 1363 GVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIK 1542
G D+R NV+ LRE IG+VSQEPVLF TI ENI G + T D++ +A K ANA +FI
Sbjct: 457 GQDIRNFNVNYLREIIGVVSQEPVLFSTTIAENICYGRGNVTMDEIKKAVKEANAYEFIM 516
Query: 1543 RLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALD 1722
+LP + T VGE+G QLSGGQKQRIAIARALV+NPKILLLDEATSALDTE+E EVQ ALD
Sbjct: 517 KLPQKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALD 576
Query: 1723 QAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXX 1902
+A+ GRTTI++AHRLST+RN D I F+ G IVE GSH ELM K+G+++ +
Sbjct: 577 KAREGRTTIVIAHRLSTVRNADVIAGFEDGVIVEQGSHSELMKKEGVYFKLVNMQTSGSQ 636
Query: 1903 XXEAGKDIEDTISESA------HSHLXXXXXXXXXXXXXXXIHQLAEEVE--ECKAPPTS 2058
++ D + + S L L E + E PP S
Sbjct: 637 IQSEEFELNDEKAATRMAPNGWKSRLFRHSTQKNLKNSQMCQKSLDVETDGLEANVPPVS 696
Query: 2059 MFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPAD----QMQANVYF 2226
K+ K N + + + P F+++++EI ++ P D Q + N++
Sbjct: 697 FLKVLKLNKTEWPYFVVGTVCAIANGGLQPAFSVIFSEIIAIFG-PGDDAVKQQKCNIFS 755
Query: 2227 WCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKL 2406
+F+ +GI F FF G+ GE LT +LR AFK +LRQD++++DD ++ TG L
Sbjct: 756 L--IFLFLGIISFFTFFLQGFTFGKAGEILTRRLRSMAFKAMLRQDMSWFDDHKNSTGAL 813
Query: 2407 CTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYF 2583
TR ATDA V+ TRL ++ +I + + I F YGWQ + G
Sbjct: 814 STRLATDAAQVQGATGTRLALIAQNIANLGTGIIISFIYGWQLTLLLLAVVPIIAVSGIV 873
Query: 2584 EMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKH 2763
EM++ G RD + LE AGK+A++A+E+IRTV SL ++ +F Y E L P
Sbjct: 874 EMKLLAGNAKRDKKELEAAGKIATEAIENIRTVVSLTQERKFESMYVEKLYGP------- 926
Query: 2764 AHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSF 2943
YRVF AI F +G+ +SF
Sbjct: 927 ----------------------------------------YRVFSAIVFGAVALGHASSF 946
Query: 2944 IPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKP--ITGNISIRNVFFNYPTRKDTKVL 3117
PD KA+L+A+ LF L E IDS S+ G+ KP GNI+ V FNYPTR + VL
Sbjct: 947 APDYAKAKLSAAHLFMLFERQPLIDSYSEEGL-KPDKFEGNITFNEVVFNYPTRANVPVL 1005
Query: 3118 QGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQV 3297
QG +L++K G+T+ALVG SGCGKST++ LLERFY+ G +++DG + LN+ LR Q+
Sbjct: 1006 QGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGTVLLDGQEAKKLNVQWLRAQL 1065
Query: 3298 CIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKG 3474
IVSQEP LFDC+I ENI YG N R V+ EIV AAK ANIH FI LP Y+T VG+KG
Sbjct: 1066 GIVSQEPILFDCSIAENIAYGDNSRVVSQDEIVSAAKAANIHPFIETLPHKYETRVGDKG 1125
Query: 3475 TQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHR 3654
TQLSGGQKQRIAIARAL+R P +LLLDEATSALDTESEK+VQEALD A++GRTC+VIAHR
Sbjct: 1126 TQLSGGQKQRIAIARALIRQPQILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHR 1185
Query: 3655 LSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
LSTIQN+D+I + G++ E GTH +L+ + IY Q
Sbjct: 1186 LSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMVSVQ 1226
>gi|27656757|gb|AAO20901.1| Mdr3 [Takifugu rubripes]
Length = 1292
Score = 973 bits (2516), Expect = 0.0
Identities = 537/1266 (42%), Positives = 757/1266 (59%), Gaps = 44/1266 (3%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F + D++LLI+GTV A+++G PL+ IV G MT F+ A + N
Sbjct: 47 LFRFADRWDVVLLISGTVMAMVNGTVMPLMCIVFGEMTDSFIYADMAQHNASGWN----S 102
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
I ++ ++ IYY VLG ++ +Y+Q++ + A R V ++R + I++Q
Sbjct: 103 TTTILNSTLQEDMQRFAIYYSVLGFVVLLAAYMQVSFWTITAGRQVKRIRSLFFHCIMQQ 162
Query: 472 QIQWFDKQQTGNLTARLTD------------------------------DLERVREGLGD 561
+I WFD TG L RLT+ D+ +++EG+GD
Sbjct: 163 EISWFDVNDTGELNTRLTEEFPASAFTLCTATLGGVDDLMDVLLFSNGSDVYKIQEGIGD 222
Query: 562 KFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYA 741
K LL+Q + F+ + +GF W +TLV++ +P + +S A SK +A+ T EQ YA
Sbjct: 223 KVGLLIQAYTTFITAFIIGFTTGWKLTLVILAVSPALAISAAFFSKVLASFTSKEQTAYA 282
Query: 742 VAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYS 921
AGA+AEE S+IRTV + +G RE++R++ L + G+ K I +GF+ L +Y
Sbjct: 283 KAGAVAEEVLSAIRTVFAFSGQTREIERYHKNLRDAKDVGVKKAISSNIAMGFTFLMIYL 342
Query: 922 SYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLR 1101
SYALAFWYGSTLI+N + G + TVFF VL G+ S+G P++ +F +ARGAA V
Sbjct: 343 SYALAFWYGSTLILNFE-YTIGNLLTVFFVVLIGAFSVGQTSPNIQNFASARGAAYKVYS 401
Query: 1102 VINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVG 1281
+I++ P ID +S +G D +KGDI FK++HF YPSR ++ +L +SL +K+G IALVG
Sbjct: 402 IIDNKPNIDSFSEDGFKPDFIKGDIEFKNIHFNYPSRPEVKILNNMSLSVKSGQTIALVG 461
Query: 1282 SSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYEN 1461
SSGCGKST + LLQRFYDP +G V IDG D+R +N+ LRE IG+VSQEPVLF TI EN
Sbjct: 462 SSGCGKSTTIQLLQRFYDPEEGAVFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITEN 521
Query: 1462 IKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVK 1641
I+ G T +++ A K +NA DFI LPD + T VG++G QLSGGQKQRIAIARALV+
Sbjct: 522 IRYGRLDVTQEEIERATKESNAYDFIMNLPDKFETLVGDRGTQLSGGQKQRIAIARALVR 581
Query: 1642 NPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIV 1821
NPKILLLDEATSALD E+E VQ ALD+ + GRTTI+VAHRLSTIRN D I F G IV
Sbjct: 582 NPKILLLDEATSALDAESETIVQAALDKVRLGRTTIVVAHRLSTIRNADIIAGFSNGKIV 641
Query: 1822 ESGSHEELMSKQGIFYDMTXXXXXXXXXXE--------AGK--DIEDTISESAHSHLXXX 1971
E G+H +LM +G+++ + E AG+ +E T+S+S+
Sbjct: 642 EQGTHSQLMEIKGVYHGLVTMQTFHNVEEENTAMSELSAGEKSPVEKTVSQSSIIRRKST 701
Query: 1972 XXXXXXXXXXXXIHQLAEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPV 2151
+ E+ + P S FK+ N + + ++ PV
Sbjct: 702 RGSSFAASEGTKEEKTEEDED---VPDVSFFKVLHLNIPEWPYILVGLICATINGAMQPV 758
Query: 2152 FALVYAEIFNVYSLP-ADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKL 2328
FA+++++I V++ P D ++ F MFV++G FV F C G+ GE LT+KL
Sbjct: 759 FAILFSKIITVFADPDRDSVRRKSEFISLMFVVIGCVSFVTMFLQGYCFGKSGEILTLKL 818
Query: 2329 RFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALG 2505
R AF ++RQD+++YD+ ++ G L TR A DA V+ RL ++ + + ++
Sbjct: 819 RLRAFTAMMRQDLSWYDNPQNTVGALTTRLAADAAQVQGAAGVRLATIMQNFANLGTSII 878
Query: 2506 IGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVH 2685
I F YGW+ G E+++ G +D + LE+AGK+A++A+E++RTV
Sbjct: 879 IAFVYGWELTLLILAVVPLIAAAGAAEIKLLAGHAAKDKKELEKAGKIATEAIENVRTVV 938
Query: 2686 SLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQA 2865
SL+R+ +F Y E LR P+ + K AH YG ++FSQ++I+F YAA F G+ +
Sbjct: 939 SLSREPKFECLYEENLRVPYKNSQKKAHVYGLTYSFSQAMIYFAYAACFRFGAWLIEAGR 998
Query: 2866 MQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGI-V 3042
M V+ V A+ + +G +F P+ KA++AAS L LI ID+LS+ G
Sbjct: 999 MDVEGVFLVVSAVLYGAMAVGEANTFAPNYAKAKMAASYLMMLINKKPAIDNLSEEGTSP 1058
Query: 3043 KPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYN 3222
+ GN+ V FNYP+R D +LQG L +K G+T+ALVG SGCGKST + LLERFY+
Sbjct: 1059 EKYDGNVHFEGVKFNYPSRPDVTILQGLNLKVKKGETLALVGSSGCGKSTTIQLLERFYD 1118
Query: 3223 QDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEA 3399
+G + +DG N++ LNI LR Q+ IVSQEP LFDC++ ENI YG N R+V+ EI
Sbjct: 1119 PREGRVSLDGVNVKQLNIHWLRSQIGIVSQEPVLFDCSLAENIAYGDNSRSVSMDEI--- 1175
Query: 3400 AKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDT 3579
YDT G+KGTQLSGGQKQR+AIARA++R+P +LLLDEATSALDT
Sbjct: 1176 ---------------RYDTQAGDKGTQLSGGQKQRVAIARAIIRNPKLLLLDEATSALDT 1220
Query: 3580 ESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQ 3759
ESEK+VQEALD A++GRTC+V+AHRLSTIQN+D IA+ G +VEKGTH +LI K +Y
Sbjct: 1221 ESEKVVQEALDQARKGRTCIVVAHRLSTIQNADCIAVFQGGVVVEKGTHQQLIAKKGVYH 1280
Query: 3760 KFCETQ 3777
Q
Sbjct: 1281 MLVTKQ 1286
>gi|17541710|ref|NP_502413.1| P-GlycoProtein related (pgp-1)
[Caenorhabditis elegans]
gi|29429182|sp|P34712|MDR1_CAEEL Multidrug resistance protein 1
(P-glycoprotein A)
gi|7505559|pir||T23476 hypothetical protein K08E7.9 - Caenorhabditis
elegans
gi|3878418|emb|CAB01232.1| Hypothetical protein K08E7.9
[Caenorhabditis elegans]
Length = 1321
Score = 973 bits (2515), Expect = 0.0
Identities = 531/1260 (42%), Positives = 767/1260 (60%), Gaps = 38/1260 (3%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
++ YT ++ LLL GT+ AVI GAG PL++I+ G ++ F+ Q V N N
Sbjct: 65 LYRYTTTLEKLLLFIGTLVAVITGAGLPLMSILQGKVSQAFINEQI------VINNNGST 118
Query: 292 LVPISLD----EFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKA 459
+P + +F +V+ Y + V M+ + + C+ AE++ ++LR+ ++K+
Sbjct: 119 FLPTGQNYTKTDFEHDVMNVVWSYAAMTVGMWAAGQITVTCYLYVAEQMNNRLRREFVKS 178
Query: 460 ILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSM 639
ILRQ+I WFD +G L +L D+LERV+EG GDK + Q + F+ G+ V F +SW +
Sbjct: 179 ILRQEISWFDTNHSGTLATKLFDNLERVKEGTGDKIGMAFQYLSQFITGFIVAFTHSWQL 238
Query: 640 TLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKREL 819
TLVM+ P+ L G ++KSM+T E YA AG + EET SSIRTV SLNG + EL
Sbjct: 239 TLVMLAVTPIQALCGFAIAKSMSTFAIRETLRYAKAGKVVEETISSIRTVVSLNGLRYEL 298
Query: 820 DRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFT 999
+R+ A+E ++ G++K ++GI G + S+ALAF+ G + +D + + G + T
Sbjct: 299 ERYSTAVEEAKKAGVLKGLFLGISFGAMQASNFISFALAFYIGVGWV-HDGSLNFGDMLT 357
Query: 1000 VFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDIS 1179
F +V+ GS +LG A P LA GTA+GAAS + V++ P ID S G +KGDI+
Sbjct: 358 TFSSVMMGSMALGLAGPQLAVLGTAQGAASGIYEVLDRKPVIDSSSKAGRKDMKIKGDIT 417
Query: 1180 FKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLI 1359
++VHF YPSR D+ +L+G++L + AG +ALVGSSGCGKSTI++LL R+YD KG++ I
Sbjct: 418 VENVHFTYPSRPDVPILRGMNLRVNAGQTVALVGSSGCGKSTIISLLLRYYDVLKGKITI 477
Query: 1360 DGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFI 1539
DGVD+R++N+ LR+ + +VSQEP LF+ TI ENI +G E T +++V ACKMANA FI
Sbjct: 478 DGVDVRDINLEFLRKNVAVVSQEPALFNCTIEENISLGKEGITREEMVAACKMANAEKFI 537
Query: 1540 KRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGAL 1719
K LP+GY T VG++G QLSGGQKQRIAIARALV+NPKILLLDEATSALD E+E VQ AL
Sbjct: 538 KTLPNGYNTLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDAESEGIVQQAL 597
Query: 1720 DQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXX 1899
D+A GRTTII+AHRLSTIRN D I K G +VE G H LM++QG++YD+
Sbjct: 598 DKAAKGRTTIIIAHRLSTIRNADLIISCKNGQVVEVGDHRALMAQQGLYYDLVTAQTFTD 657
Query: 1900 XXXEAGK---DIEDTISESAHSHLXXXXXXXXXXXXXXXIH------------------- 2013
A + E++++ H +
Sbjct: 658 AVDSAAEGKFSRENSVARQTSEHEGLSRQASEMDDIMNRVRSSTIGSITNGPVIDEKEER 717
Query: 2014 -------QLAEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAE 2172
+L +E+EE A T++F+I + P +++ +
Sbjct: 718 IGKDALSRLKQELEENNAQKTNLFEILYHARPHALSLFIGMSTATIGGFIYPTYSVFFTS 777
Query: 2173 IFNVYS-LPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKN 2349
NV++ PAD + +FW MF+++ + F +G ESLT LR + F+N
Sbjct: 778 FMNVFAGNPADFLSQG-HFWALMFLVLAAAQGICSFLMTFFMGIASESLTRDLRNKLFRN 836
Query: 2350 LLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVFT-RLPVVLASIVTICGALGIGFYYGW 2526
+L Q I F+D ++ +GK+ TR ATD PN+R R V+ ++V++ +G+ F+YGW
Sbjct: 837 VLSQHIGFFDSPQNASGKISTRLATDVPNLRTAIDFRFSTVITTLVSMVAGIGLAFFYGW 896
Query: 2527 QXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQ 2706
Q G Y + GK ++ ++GK+A +A+E++RTV +L R++
Sbjct: 897 QMALLIIAILPIVAFGQYLRGRRFTGKNVKSASEFADSGKIAIEAIENVRTVQALAREDT 956
Query: 2707 FHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLG--SIFVNQQAMQPID 2880
F+ +CE L P +K A G + + S+++ + A+ +G I + MQP+
Sbjct: 957 FYENFCEKLDIPHKEAIKEAFIQGLSYGCASSVLYLLNTCAYRMGLALIITDPPTMQPMR 1016
Query: 2881 VYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGN 3060
V RV +AI+ +G TS+ P+ KA A ++F ++ + IDSLS +G K + G
Sbjct: 1017 VLRVMYAITISTSTLGFATSYFPEYAKATFAGGIIFGMLRKISKIDSLSLAGEKKKLYGK 1076
Query: 3061 ISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMI 3240
+ +NV F YP R + ++L+G + ++ G+T+ALVG SGCGKST++ LLERFY+ G I
Sbjct: 1077 VIFKNVRFAYPERPEIEILKGLSFSVEPGQTLALVGPSGCGKSTVVALLERFYDTLGGEI 1136
Query: 3241 MIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANI 3417
IDG I+ LN R Q+ IVSQEPTLFDC+I ENI YG + +VT ++ EAA++ANI
Sbjct: 1137 FIDGSEIKTLNPEHTRSQIAIVSQEPTLFDCSIAENIIYGLDPSSVTMAQVEEAARLANI 1196
Query: 3418 HNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIV 3597
HNFI LP+G++T VG++GTQLSGGQKQRIAIARALVR+P +LLLDEATSALDTESEK+V
Sbjct: 1197 HNFIAELPEGFETRVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEKVV 1256
Query: 3598 QEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
QEALD A++GRTC+VIAHRL+T+ N+D IA+VS G I+EKGTH +L+ + Y K + Q
Sbjct: 1257 QEALDRAREGRTCIVIAHRLNTVMNADCIAVVSNGTIIEKGTHTQLMSEKGAYYKLTQKQ 1316
Score = 327 bits (837), Expect = 2e-87
Identities = 197/506 (38%), Positives = 286/506 (55%), Gaps = 2/506 (0%)
Frame = +1
Query: 2281 SANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRY-VFTR 2457
+ C E + +LR E K++LRQ+I+++D GT L T+ + V+ +
Sbjct: 156 TVTCYLYVAEQMNNRLRREFVKSILRQEISWFDTNHSGT--LATKLFDNLERVKEGTGDK 213
Query: 2458 LPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEE 2637
+ + + + F + WQ + G+ + IR+T +
Sbjct: 214 IGMAFQYLSQFITGFIVAFTHSWQLTLVMLAVTPIQALCGFAIAKSMSTFAIRETLRYAK 273
Query: 2638 AGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFM 2817
AGKV + + IRTV SLN Y + E + G F Q+ F
Sbjct: 274 AGKVVEETISSIRTVVSLNGLRYELERYSTAVEEAKKAGVLKGLFLGISFGAMQASNFIS 333
Query: 2818 YAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLI 2997
+A AFY+G +V+ ++ D+ F ++ +G + + A+ AAS ++ ++
Sbjct: 334 FALAFYIGVGWVHDGSLNFGDMLTTFSSVMMGSMALGLAGPQLAVLGTAQGAASGIYEVL 393
Query: 2998 EHPTPIDSLSDSGIVK-PITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHS 3174
+ IDS S +G I G+I++ NV F YP+R D +L+G L + AG+TVALVG S
Sbjct: 394 DRKPVIDSSSKAGRKDMKIKGDITVENVHFTYPSRPDVPILRGMNLRVNAGQTVALVGSS 453
Query: 3175 GCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENIC 3354
GCGKSTI+ LL R+Y+ KG I IDG ++R++N+ LR+ V +VSQEP LF+CTI ENI
Sbjct: 454 GCGKSTIISLLLRYYDVLKGKITIDGVDVRDINLEFLRKNVAVVSQEPALFNCTIEENIS 513
Query: 3355 YGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRS 3534
G +T +E+V A KMAN FI LP+GY+T VG++GTQLSGGQKQRIAIARALVR+
Sbjct: 514 LG-KEGITREEMVAACKMANAEKFIKTLPNGYNTLVGDRGTQLSGGQKQRIAIARALVRN 572
Query: 3535 PSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVE 3714
P +LLLDEATSALD ESE IVQ+ALD A +GRT ++IAHRLSTI+N+D+I G++VE
Sbjct: 573 PKILLLDEATSALDAESEGIVQQALDKAAKGRTTIIIAHRLSTIRNADLIISCKNGQVVE 632
Query: 3715 KGTHDELIRKSEIYQKFCETQRIVES 3792
G H L+ + +Y Q ++
Sbjct: 633 VGDHRALMAQQGLYYDLVTAQTFTDA 658
>gi|283551|pir||S27337 multidrug resistance protein A - Caenorhabditis
elegans
gi|6809|emb|CAA46190.1| P-glycoprotein A [Caenorhabditis elegans]
Length = 1321
Score = 972 bits (2513), Expect = 0.0
Identities = 531/1260 (42%), Positives = 767/1260 (60%), Gaps = 38/1260 (3%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
++ YT ++ LLL GT+ AVI GAG PL++I+ G ++ F+ Q V N N
Sbjct: 65 LYRYTTTLEKLLLFIGTLVAVITGAGLPLMSILQGKVSQAFINEQI------VINNNGST 118
Query: 292 LVPISLD----EFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKA 459
+P + +F +V+ Y + V M+ + + C+ AE++ ++LR+ ++K+
Sbjct: 119 FLPTGQNYTKTDFEHDVMNVVWSYAAMTVGMWAAGQIIVTCYLYVAEQMNNRLRREFVKS 178
Query: 460 ILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSM 639
ILRQ+I WFD +G L +L D+LERV+EG GDK + Q + F+ G+ V F +SW +
Sbjct: 179 ILRQEISWFDTNHSGTLATKLFDNLERVKEGTGDKIGMAFQYLSQFITGFIVAFTHSWQL 238
Query: 640 TLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKREL 819
TLVM+ P+ L G ++KSM+T E YA AG + EET SSIRTV SLNG + EL
Sbjct: 239 TLVMLAVTPIQALCGFAIAKSMSTFAIRETLRYAKAGKVVEETISSIRTVVSLNGLRYEL 298
Query: 820 DRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFT 999
+R+ A+E ++ G++K ++GI G + S+ALAF+ G + +D + + G + T
Sbjct: 299 ERYSTAVEEAKKAGVLKGLFLGISFGAMQASNFISFALAFYIGVGWV-HDGSLNFGDMLT 357
Query: 1000 VFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDIS 1179
F +V+ GS +LG A P LA GTA+GAAS + V++ P ID S G +KGDI+
Sbjct: 358 TFSSVMMGSMALGLAGPQLAVLGTAQGAASGIYEVLDRKPVIDSSSKAGRKDMKIKGDIT 417
Query: 1180 FKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLI 1359
++VHF YPSR D+ +L+G++L + AG +ALVGSSGCGKSTI++LL R+YD KG++ I
Sbjct: 418 VENVHFTYPSRPDVPILRGMNLRVNAGQTVALVGSSGCGKSTIISLLLRYYDVLKGKITI 477
Query: 1360 DGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFI 1539
DGVD+R++N+ LR+ + +VSQEP LF+ TI ENI +G E T +++V ACKMANA FI
Sbjct: 478 DGVDVRDINLEFLRKNVAVVSQEPALFNCTIEENISLGKEGITREEMVAACKMANAEKFI 537
Query: 1540 KRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGAL 1719
K LP+GY T VG++G QLSGGQKQRIAIARALV+NPKILLLDEATSALD E+E VQ AL
Sbjct: 538 KTLPNGYNTLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDAESEGIVQQAL 597
Query: 1720 DQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXX 1899
D+A GRTTII+AHRLSTIRN D I K G +VE G H LM++QG++YD+
Sbjct: 598 DKAAKGRTTIIIAHRLSTIRNADLIISCKNGQVVEVGDHRALMAQQGLYYDLVTAQTFTD 657
Query: 1900 XXXEAGK---DIEDTISESAHSHLXXXXXXXXXXXXXXXIH------------------- 2013
A + E++++ H +
Sbjct: 658 AVDSAAEGKFSRENSVARQTSEHEGLSRQASEMDDIMNRVRSSTIGSITNGPVIDEKEER 717
Query: 2014 -------QLAEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAE 2172
+L +E+EE A T++F+I + P +++ +
Sbjct: 718 IGKDALSRLKQELEENNAQKTNLFEILYHARPHALSLFIGMSTATIGGFIYPTYSVFFTS 777
Query: 2173 IFNVYS-LPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKN 2349
NV++ PAD + +FW MF+++ + F +G ESLT LR + F+N
Sbjct: 778 FMNVFAGNPADFLSQG-HFWALMFLVLAAAQGICSFLMTFFMGIASESLTRDLRNKLFRN 836
Query: 2350 LLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVFT-RLPVVLASIVTICGALGIGFYYGW 2526
+L Q I F+D ++ +GK+ TR ATD PN+R R V+ ++V++ +G+ F+YGW
Sbjct: 837 VLSQHIGFFDSPQNASGKISTRLATDVPNLRTAIDFRFSTVITTLVSMVAGIGLAFFYGW 896
Query: 2527 QXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQ 2706
Q G Y + GK ++ ++GK+A +A+E++RTV +L R++
Sbjct: 897 QMALLIIAILPIVAFGQYLRGRRFTGKNVKSASEFADSGKIAIEAIENVRTVQALAREDT 956
Query: 2707 FHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLG--SIFVNQQAMQPID 2880
F+ +CE L P +K A G + + S+++ + A+ +G I + MQP+
Sbjct: 957 FYENFCEKLDIPHKEAIKEAFIQGLSYGCASSVLYLLNTCAYRMGLALIITDPPTMQPMR 1016
Query: 2881 VYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGN 3060
V RV +AI+ +G TS+ P+ KA A ++F ++ + IDSLS +G K + G
Sbjct: 1017 VLRVMYAITISTSTLGFATSYFPEYAKATFAGGIIFGMLRKISKIDSLSLAGEKKKLYGK 1076
Query: 3061 ISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMI 3240
+ +NV F YP R + ++L+G + ++ G+T+ALVG SGCGKST++ LLERFY+ G I
Sbjct: 1077 VIFKNVRFAYPERPEIEILKGLSFSVEPGQTLALVGPSGCGKSTVVALLERFYDTLGGEI 1136
Query: 3241 MIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANI 3417
IDG I+ LN R Q+ IVSQEPTLFDC+I ENI YG + +VT ++ EAA++ANI
Sbjct: 1137 FIDGSEIKTLNPEHTRSQIAIVSQEPTLFDCSIAENIIYGLDPSSVTMAQVEEAARLANI 1196
Query: 3418 HNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIV 3597
HNFI LP+G++T VG++GTQLSGGQKQRIAIARALVR+P +LLLDEATSALDTESEK+V
Sbjct: 1197 HNFIAELPEGFETRVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEKVV 1256
Query: 3598 QEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
QEALD A++GRTC+VIAHRL+T+ N+D IA+VS G I+EKGTH +L+ + Y K + Q
Sbjct: 1257 QEALDRAREGRTCIVIAHRLNTVMNADCIAVVSNGTIIEKGTHTQLMSEKGAYYKLTQKQ 1316
Score = 327 bits (838), Expect = 1e-87
Identities = 199/515 (38%), Positives = 290/515 (55%), Gaps = 6/515 (1%)
Frame = +1
Query: 2266 VGFFTSANCLGRC----GESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAP 2433
VG + + + C E + +LR E K++LRQ+I+++D GT L T+ +
Sbjct: 147 VGMWAAGQIIVTCYLYVAEQMNNRLRREFVKSILRQEISWFDTNHSGT--LATKLFDNLE 204
Query: 2434 NVRY-VFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQ 2610
V+ ++ + + + F + WQ + G+ +
Sbjct: 205 RVKEGTGDKIGMAFQYLSQFITGFIVAFTHSWQLTLVMLAVTPIQALCGFAIAKSMSTFA 264
Query: 2611 IRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFA 2790
IR+T +AGKV + + IRTV SLN Y + E + G F
Sbjct: 265 IRETLRYAKAGKVVEETISSIRTVVSLNGLRYELERYSTAVEEAKKAGVLKGLFLGISFG 324
Query: 2791 FSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARL 2970
Q+ F +A AFY+G +V+ ++ D+ F ++ +G + + A+
Sbjct: 325 AMQASNFISFALAFYIGVGWVHDGSLNFGDMLTTFSSVMMGSMALGLAGPQLAVLGTAQG 384
Query: 2971 AASLLFYLIEHPTPIDSLSDSGIVK-PITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAG 3147
AAS ++ +++ IDS S +G I G+I++ NV F YP+R D +L+G L + AG
Sbjct: 385 AASGIYEVLDRKPVIDSSSKAGRKDMKIKGDITVENVHFTYPSRPDVPILRGMNLRVNAG 444
Query: 3148 KTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLF 3327
+TVALVG SGCGKSTI+ LL R+Y+ KG I IDG ++R++N+ LR+ V +VSQEP LF
Sbjct: 445 QTVALVGSSGCGKSTIISLLLRYYDVLKGKITIDGVDVRDINLEFLRKNVAVVSQEPALF 504
Query: 3328 DCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRI 3507
+CTI ENI G +T +E+V A KMAN FI LP+GY+T VG++GTQLSGGQKQRI
Sbjct: 505 NCTIEENISLG-KEGITREEMVAACKMANAEKFIKTLPNGYNTLVGDRGTQLSGGQKQRI 563
Query: 3508 AIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIA 3687
AIARALVR+P +LLLDEATSALD ESE IVQ+ALD A +GRT ++IAHRLSTI+N+D+I
Sbjct: 564 AIARALVRNPKILLLDEATSALDAESEGIVQQALDKAAKGRTTIIIAHRLSTIRNADLII 623
Query: 3688 IVSEGKIVEKGTHDELIRKSEIYQKFCETQRIVES 3792
G++VE G H L+ + +Y Q ++
Sbjct: 624 SCKNGQVVEVGDHRALMAQQGLYYDLVTAQTFTDA 658
>gi|72475|pir||DVMS1A multidrug resistance protein 1a - mouse
(fragment)
gi|200330|gb|AAA03243.1| mdr1a protein
Length = 1104
Score = 957 bits (2474), Expect = 0.0
Identities = 510/1100 (46%), Positives = 711/1100 (64%), Gaps = 16/1100 (1%)
Frame = +1
Query: 526 DDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSM 705
DD+ ++ EG+GDK + Q A F G+ +GF W +TLV++ +P++ LS +K +
Sbjct: 1 DDVSKINEGIGDKIGMFFQAMATFFGGFIIGFTRGWKLTLVILAISPVLGLSAGIWAKIL 60
Query: 706 ATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMG 885
++ T E YA AGA+AEE ++IRTV + G K+EL+R+ N LE ++ GI K
Sbjct: 61 SSFTDKELHAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNNNLEEAKRLGIKKAITAN 120
Query: 886 IGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASF 1065
I +G + L +Y+SYALAFWYG++L+I+ + G + TVFF+VL G+ S+G A P++ +F
Sbjct: 121 ISMGAAFLLIYASYALAFWYGTSLVISKE-YSIGQVLTVFFSVLIGAFSVGQASPNIEAF 179
Query: 1066 GTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISL 1245
ARGAA V ++I++ P ID +S G DN++G++ FK++HF YPSRK++ +LKG++L
Sbjct: 180 ANARGAAYEVFKIIDNKPSIDSFSKSGHKPDNIQGNLEFKNIHFSYPSRKEVQILKGLNL 239
Query: 1246 ELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQ 1425
++K+G +ALVG+SGCGKST V L+QR YDP G V IDG D+R +NV LRE IG+VSQ
Sbjct: 240 KVKSGQTVALVGNSGCGKSTTVQLMQRLYDPLDGMVSIDGQDIRTINVRYLREIIGVVSQ 299
Query: 1426 EPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQ 1605
EPVLF TI ENI+ G E T D++ +A K ANA DFI +LP + T VGE+G +SGGQ
Sbjct: 300 EPVLFATTIAENIRYGREDVTMDEIEKAVKEANAYDFIMKLPHQFDTLVGERGAHVSGGQ 359
Query: 1606 KQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNV 1785
KQRIAIARALV+NPKILLLDEATSALDTE+E VQ ALD+A+ GRTTI++AHRLST+RN
Sbjct: 360 KQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTVRNA 419
Query: 1786 DRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXX---EA--GKDIEDTISESA 1950
D I F G IVE G+H+ELM ++GI++ + EA KD D + S+
Sbjct: 420 DVIAGFDGGVIVEQGNHDELMREKGIYFKLVMTQTAGNEIELGNEACKSKDEIDNLDMSS 479
Query: 1951 HSHLXXXXXXXXXXXXXXXIHQLAEEVEECKA-----PPTSMFKIFKFNGDKVGWXXXXX 2115
H ++ +A PP S ++I K N + +
Sbjct: 480 KDSGSSLIRRRSTRKSICGPHDQDRKLSTKEALDEDVPPASFWRILKLNSTEWPYFVVGI 539
Query: 2116 XXXXXXXSVTPVFALVYAEIFNVYSL--PADQMQANVYFWCGMFVLMGITFFVGFFTSAN 2289
+ P F+++++++ V++ P + + N + +F+++GI F+ FF
Sbjct: 540 FCAIINGGLQPAFSVIFSKVVGVFTNGGPPETQRQNSNLFSLLFLILGIISFITFFLQGF 599
Query: 2290 CLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVF-TRLPV 2466
G+ GE LT +LR+ FK++LRQD++++DD ++ TG L TR A DA V+ +RL V
Sbjct: 600 TFGKAGEILTKRLRYMVFKSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGATGSRLAV 659
Query: 2467 VLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGK 2646
+ +I + + I YGWQ + G EM+M G+ ++D + LE +GK
Sbjct: 660 IFQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGK 719
Query: 2647 VASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAA 2826
+A++A+E+ RTV SL R+++F Y + L+ P+ +K AH +G F+F+Q++++F YAA
Sbjct: 720 IATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNAMKKAHVFGITFSFTQAMMYFSYAA 779
Query: 2827 AFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHP 3006
F G+ V QQ M +V VF AI F +G +SF PD KA ++AS + +IE
Sbjct: 780 CFRFGAYLVTQQLMTFENVLLVFSAIVFGAMAVGQVSSFAPDYAKATVSASHIIRIIEKT 839
Query: 3007 TPIDSLSDSGIVKP--ITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGC 3180
IDS S G+ KP + GN+ V FNYPTR VLQG +L++K G+T+ALVG SGC
Sbjct: 840 PEIDSYSTQGL-KPNMLEGNVQFSGVVFNYPTRPSIPVLQGLSLEVKKGQTLALVGSSGC 898
Query: 3181 GKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYG 3360
GKST++ LLERFY+ G + +DG I+ LN+ LR Q+ IVSQEP LFDC+I ENI YG
Sbjct: 899 GKSTVVQLLERFYDPMAGSVFLDGKEIKQLNVQWLRAQLGIVSQEPILFDCSIAENIAYG 958
Query: 3361 TN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSP 3537
N R V+Y+EIV AAK ANIH FI LPD Y+T VG+KGTQLSGGQKQRIAIARALVR P
Sbjct: 959 DNSRVVSYEEIVRAAKEANIHQFIDSLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQP 1018
Query: 3538 SVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEK 3717
+LLLDEATSALDTESEK+VQEALD A++GRTC+VIAHRLSTIQN+D+I ++ GK+ E
Sbjct: 1019 HILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVIQNGKVKEH 1078
Query: 3718 GTHDELIRKSEIYQKFCETQ 3777
GTH +L+ + IY Q
Sbjct: 1079 GTHQQLLAQKGIYFSMVSVQ 1098
Score = 418 bits (1075), Expect = e-115
Identities = 230/580 (39%), Positives = 347/580 (59%), Gaps = 5/580 (0%)
Frame = +1
Query: 151 ITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEV 330
+ G A+I+G P +++ + VF P NS +
Sbjct: 536 VVGIFCAIINGGLQPAFSVIFSKVVGVFTNGG-----------------PPETQRQNSNL 578
Query: 331 VKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD--KQQTG 504
+ + +L+LG++ F T ++Q F E L +LR K++LRQ + WFD K TG
Sbjct: 579 --FSLLFLILGIISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDDPKNTTG 636
Query: 505 NLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSG 684
LT RL +D +V+ G + A++ Q A G + Y W +TL+++ P+I ++G
Sbjct: 637 ALTTRLANDAAQVKGATGSRLAVIFQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAIAG 696
Query: 685 AKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGI 864
K ++ + +++ +G IA E + RTV SL ++ + +L++ + +
Sbjct: 697 VVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNAM 756
Query: 865 VKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIIND-PTFDRGLIFTVFFAVLSGSTSLGG 1041
K GI F+ MY SYA F +G+ L+ TF+ L+ VF A++ G+ ++G
Sbjct: 757 KKAHVFGITFSFTQAMMYFSYAACFRFGAYLVTQQLMTFENVLL--VFSAIVFGAMAVGQ 814
Query: 1042 ALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDI 1221
+ A +AS ++R+I P+ID YS +G+ + ++G++ F V F YP+R I
Sbjct: 815 VSSFAPDYAKATVSASHIIRIIEKTPEIDSYSTQGLKPNMLEGNVQFSGVVFNYPTRPSI 874
Query: 1222 HVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLR 1401
VL+G+SLE+K G +ALVGSSGCGKST+V LL+RFYDP G V +DG +++++NV LR
Sbjct: 875 PVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSVFLDGKEIKQLNVQWLR 934
Query: 1402 EQIGIVSQEPVLFDGTIYENIKMGNEH--ATHDQVVEACKMANANDFIKRLPDGYGTRVG 1575
Q+GIVSQEP+LFD +I ENI G+ +++++V A K AN + FI LPD Y TRVG
Sbjct: 935 AQLGIVSQEPILFDCSIAENIAYGDNSRVVSYEEIVRAAKEANIHQFIDSLPDKYNTRVG 994
Query: 1576 EKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIV 1755
+KG QLSGGQKQRIAIARALV+ P ILLLDEATSALDTE+E+ VQ ALD+A+ GRT I++
Sbjct: 995 DKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVI 1054
Query: 1756 AHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM 1875
AHRLSTI+N D I V + G + E G+H++L++++GI++ M
Sbjct: 1055 AHRLSTIQNADLIVVIQNGKVKEHGTHQQLLAQKGIYFSM 1094
>gi|6472653|dbj|BAA87071.1| multi-drug resistance related mRNA [Felis
catus]
Length = 1163
Score = 956 bits (2472), Expect = 0.0
Identities = 522/1167 (44%), Positives = 742/1167 (62%), Gaps = 19/1167 (1%)
Frame = +1
Query: 178 HGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPIS--LDEFNSEVVKYCIYY 351
HGA PL+ +V G MT F A S + + N+ E +V S ++ E+ Y YY
Sbjct: 1 HGAALPLMMLVFGDMTDSFANAGISRNLTTL-NITGESIVNDSYFINRLEEEMTTYAYYY 59
Query: 352 LVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTARLTDD 531
+G + +Y+Q++ + A R + K+R+ + AI+RQ++ WFD G L RLTDD
Sbjct: 60 SGIGAGVLVAAYIQVSFWCLAAGRQILKIRKQFFHAIMRQEVGWFDVHDVGELNTRLTDD 119
Query: 532 LERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMAT 711
+ ++ EG+GDK + Q A F G+ VGF W +TLV++ +P++ LS A +K +++
Sbjct: 120 VSKINEGIGDKIGMFFQSMATFFIGFIVGFTRGWKLTLVILAISPVLGLSAAIWAKILSS 179
Query: 712 RTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGIG 891
T E YA AGA+AEE ++IRTV + G K+EL+R+ LE ++ GI K I
Sbjct: 180 FTDKELLAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNKNLEEAKRIGIKKAITANIS 239
Query: 892 VGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGT 1071
+G + L +Y+SYALAFWYG++L+++ + G + TVFF+VL G+ S+G A P + +F
Sbjct: 240 IGIAFLLIYASYALAFWYGTSLVLSHE-YSIGQVLTVFFSVLIGAFSVGQASPSIEAFAN 298
Query: 1072 ARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLEL 1251
ARGAA + ++I++ P ID YS G DN+KG++ FK+VHF YPSRK++ +LKG++L++
Sbjct: 299 ARGAAYEIFKIIDNKPSIDSYSKNGHKPDNIKGNLEFKNVHFSYPSRKEVKILKGLNLKV 358
Query: 1252 KAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEP 1431
++G +ALVG+SGCGKST V L+QR YDPT G V IDG D+R +NV LRE IG+VSQEP
Sbjct: 359 QSGQTVALVGNSGCGKSTTVQLMQRLYDPTDGMVSIDGQDIRTINVRYLREIIGVVSQEP 418
Query: 1432 VLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQ 1611
VLF TI ENI+ G E+ T +++ +A K ANA DFI +LP+ + T VGE+G QLSGGQKQ
Sbjct: 419 VLFATTIAENIRYGRENVTMEEIEKAVKEANAYDFIMKLPNKFDTLVGERGAQLSGGQKQ 478
Query: 1612 RIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDR 1791
RIAIARALV+NPKILLLDEATSALD+E+E VQ ALD+A+ GRTTI+VAHRLSTIRN D
Sbjct: 479 RIAIARALVRNPKILLLDEATSALDSESEAVVQVALDKARKGRTTIVVAHRLSTIRNADV 538
Query: 1792 IFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXXEAGKDIEDTISE--------- 1944
I F G IVE G+H+ELM ++GI++ + E + ++ISE
Sbjct: 539 IAGFDDGVIVEKGNHDELMKEEGIYFKLV-TMQTRGNEIELENAVYESISEIDALEMSPK 597
Query: 1945 -SAHSHLXXXXXXXXXXXXXXXIHQLA--EEVEECKAPPTSMFKIFKFNGDKVGWXXXXX 2115
S S + +L E ++E + PP S ++I K N + +
Sbjct: 598 DSGSSLIRRRSTRKSIHASQGQDRKLGTKENLDE-RVPPVSFWRILKLNITEWPYFVVGI 656
Query: 2116 XXXXXXXSVTPVFALVYAEIFNVYSLPAD--QMQANVYFWCGMFVLMGITFFVGFFTSAN 2289
+ P F+++ + I V++ D + N + +F+++GI + FF
Sbjct: 657 FCAIINGGLQPAFSVILSRIIGVFTRVEDPETKRQNSNIFSLLFLVLGIISSITFFLQGF 716
Query: 2290 CLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPV 2466
G+ GE LT +LR+ F+++LRQD++++DD ++ TG L TR A DA V+ + +RL +
Sbjct: 717 TFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAI 776
Query: 2467 VLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGK 2646
+ +I + + I YGWQ + G EM+M G+ ++D + LE AGK
Sbjct: 777 ITQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGAGK 836
Query: 2647 VASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAA 2826
VA++A+E+ RTV SL R+++F + Y + L+ P+ +L+ AH +G F+ +Q++++F YA
Sbjct: 837 VATEAIENFRTVVSLTREQKFEYMYAQSLQVPYRNSLRKAHIFGISFSITQAMMYFSYAG 896
Query: 2827 AFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHP 3006
F G+ V + M DV VF AI F +G +SF PD KA+++A+ + +IE
Sbjct: 897 CFRFGAYLVAHEFMDFQDVLLVFSAIVFGAMAVGQVSSFAPDYAKAKVSAAHVIMIIEKI 956
Query: 3007 TPIDSLSDSGIV-KPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCG 3183
IDS S G++ + GN++ V FNYPTR D VLQG +L++K G+T+ALVG SGCG
Sbjct: 957 PLIDSYSTEGLMPNTLEGNVTFNEVMFNYPTRPDIPVLQGLSLEVKKGQTLALVGSSGCG 1016
Query: 3184 KSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGT 3363
KST++ LLERFY+ G ++IDG I++LN+ LR + IVSQEP LFDC+IGENI YG
Sbjct: 1017 KSTVVQLLERFYDPMAGTVLIDGKEIKHLNVQWLRAHMGIVSQEPILFDCSIGENIAYGD 1076
Query: 3364 N-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPS 3540
N R V+ +EIV AAK ANIH FI LPD Y+T VG+KGTQLSGGQKQRIAIARALVR P
Sbjct: 1077 NSRVVSQEEIVRAAKEANIHPFIETLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPR 1136
Query: 3541 VLLLDEATSALDTESEKIVQEALDAAK 3621
+LLLDEATSALDTESEK+VQEALD A+
Sbjct: 1137 ILLLDEATSALDTESEKVVQEALDKAR 1163
Score = 348 bits (892), Expect = 7e-94
Identities = 214/531 (40%), Positives = 310/531 (58%), Gaps = 5/531 (0%)
Frame = +1
Query: 2200 DQMQANVYFWCGMF--VLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAF 2373
++M Y++ G+ VL+ V F+ CL G + +K+R + F ++RQ++ +
Sbjct: 50 EEMTTYAYYYSGIGAGVLVAAYIQVSFW----CLA-AGRQI-LKIRKQFFHAIMRQEVGW 103
Query: 2374 YDDLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXX 2550
+D H G+L TR D + + ++ + S+ T +GF GW+
Sbjct: 104 FDV--HDVGELNTRLTDDVSKINEGIGDKIGMFFQSMATFFIGFIVGFTRGWKLTLVILA 161
Query: 2551 XXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEY 2730
+ ++ ++ +AG VA + + IRTV + Q++ Y +
Sbjct: 162 ISPVLGLSAAIWAKILSSFTDKELLAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNKN 221
Query: 2731 LREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISF 2910
L E +K A T + LI+ YA AF+ G+ V V VFF++
Sbjct: 222 LEEAKRIGIKKAITANISIGIAFLLIYASYALAFWYGTSLVLSHEYSIGQVLTVFFSVLI 281
Query: 2911 CGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKP--ITGNISIRNVFF 3084
+G + I AR AA +F +I++ IDS S +G KP I GN+ +NV F
Sbjct: 282 GAFSVGQASPSIEAFANARGAAYEIFKIIDNKPSIDSYSKNGH-KPDNIKGNLEFKNVHF 340
Query: 3085 NYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIR 3264
+YP+RK+ K+L+G L +++G+TVALVG+SGCGKST + L++R Y+ GM+ IDG +IR
Sbjct: 341 SYPSRKEVKILKGLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTDGMVSIDGQDIR 400
Query: 3265 NLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPD 3444
+N+ LRE + +VSQEP LF TI ENI YG NVT +EI +A K AN ++FI+ LP+
Sbjct: 401 TINVRYLREIIGVVSQEPVLFATTIAENIRYG-RENVTMEEIEKAVKEANAYDFIMKLPN 459
Query: 3445 GYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQ 3624
+DT VGE+G QLSGGQKQRIAIARALVR+P +LLLDEATSALD+ESE +VQ ALD A++
Sbjct: 460 KFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDSESEAVVQVALDKARK 519
Query: 3625 GRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
GRT +V+AHRLSTI+N+DVIA +G IVEKG HDEL+++ IY K Q
Sbjct: 520 GRTTIVVAHRLSTIRNADVIAGFDDGVIVEKGNHDELMKEEGIYFKLVTMQ 570
>gi|45361353|ref|NP_989254.1| hypothetical protein MGC76216 [Xenopus
tropicalis]
gi|39645391|gb|AAH63924.1| Hypothetical protein MGC76216 [Xenopus
tropicalis]
Length = 1261
Score = 940 bits (2429), Expect = 0.0
Identities = 513/1232 (41%), Positives = 732/1232 (58%), Gaps = 7/1232 (0%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
IF + +D+ L+I GT+ A+ G+ +PL+ +V G M+ FL NS
Sbjct: 42 IFQFADWLDIFLMIIGTLGAIGCGSCYPLMNVVFGEMSDSFL-CHNSSL--------QNS 92
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
E+ K+ +YY LG + F Y+Q++C+ A R K+R+ + ++L Q
Sbjct: 93 SACAKFKPIEEEIQKFSLYYAGLGFAVLFCGYLQVSCWVVAASRQTRKMRKAFFHSVLSQ 152
Query: 472 QIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVM 651
+I WFD ++G+L RLT+++ ++ +G+GDK A Q ++G +G W + LV+
Sbjct: 153 EIGWFDVTKSGDLNTRLTENINKINDGIGDKVAHFFQNTTICVSGILIGLIQGWKLALVI 212
Query: 652 MGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFY 831
+ +P++ L+ A S+ + + T E YA AGA+A+E SSIRTV + G ++E+ R+
Sbjct: 213 LATSPVLTLASAMFSRIVVSLTTKELAAYAKAGAVAQEVLSSIRTVVAFGGEEKEIKRYT 272
Query: 832 NALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFA 1011
L+ + GI K +G N Y++Y + FWYG+TL++ D + G + VFF
Sbjct: 273 ENLKQAKDIGIKKSIASQFALGLVNGAFYATYGVGFWYGTTLVLEDDDYTIGDVMAVFFN 332
Query: 1012 VLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDV 1191
V S ++G A H +F AR AAS++ +VI ID +S +G DN+KG+I KD+
Sbjct: 333 VSFSSYAIGQAASHFEAFHIARAAASSIFKVIKQSSSIDNFSNDGFKPDNIKGNIELKDI 392
Query: 1192 HFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVD 1371
+F YPSR + VL G++L +K+G +ALVG SGCGKSTIV LLQR YDP +G + +DG D
Sbjct: 393 YFSYPSRPGVKVLNGLNLSVKSGQTVALVGQSGCGKSTIVQLLQRLYDPKEGTLAVDGHD 452
Query: 1372 LREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLP 1551
++ +NV RE IG+VSQEPVLF TI +NI+ G + T +++ +A K ANA DFI LP
Sbjct: 453 IKSLNVTYYRELIGVVSQEPVLFGTTIKQNIRYGRDDVTDEEIEKAVKEANAYDFIMALP 512
Query: 1552 DGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQ 1731
D Y T VGE+G QLSGGQKQRIA+ARALV+NPKILLLDEATSALDT +E VQ ALD+A+
Sbjct: 513 DKYETLVGERGAQLSGGQKQRIAVARALVRNPKILLLDEATSALDTGSEAVVQAALDKAR 572
Query: 1732 AGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXXE 1911
GRTTI+VAHRLSTI D I V G + E G+H ELM K+GI++ + +
Sbjct: 573 KGRTTIVVAHRLSTIWTADVIVVIDNGAVAEQGTHSELMEKKGIYFSL--ATAQTVQLSD 630
Query: 1912 AGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECK--APPTSMFKIFKFNG 2085
+ E + + I + +E EE K P S F++ K N
Sbjct: 631 DNETTEKNQNGIIYEKASLIQRFNSQTSLKSKILEDEDEEEESKKDLPTVSFFQLLKLNR 690
Query: 2086 DKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANVYFWCGM-FVLMGITF 2262
+ + S+ P+F + YA I V++ + C + F L G+
Sbjct: 691 SEWPYILLGIIAAGVIGSLLPLFCIFYARIIAVFASNDPETIRKESDLCSLIFGLTGVVI 750
Query: 2263 FVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVR 2442
+ + GR GE+LTM+LR AFK +++QDIA++DD + TG L TR ATDA ++
Sbjct: 751 LLAYIARGYMFGRSGETLTMRLRHMAFKAMIQQDIAWFDDKDNNTGALTTRLATDASEIQ 810
Query: 2443 YVF-TRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRD 2619
RL + +++ I + I F YGW+ + G E G RD
Sbjct: 811 TATGYRLGFLAENLIGIVLTVIIAFVYGWELALLGLAMAPFMVICGLLEFSALTGFATRD 870
Query: 2620 TQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQ 2799
+ L+ AGK+A++AV++IRT+ SL R+ F Y E L++P+ +L+ A YG FA
Sbjct: 871 KKQLQRAGKIATEAVDNIRTLVSLTRERTFEEMYSESLQKPYRNSLRKAQIYGLYFAIGH 930
Query: 2800 SLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAAS 2979
+ +F +AA F G+ + + + + VF I+F +G T +F PD KA AA
Sbjct: 931 AFYYFTHAALFCFGAYLIKYERINVEEALLVFSVITFGAMTLGTTLTFAPDYAKATSAAR 990
Query: 2980 LLFYLIEHPTPIDSLSDSGIVKP--ITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKT 3153
LF L E IDS S G KP +G++ RNV FNYPTR D +VL+ + +++G+T
Sbjct: 991 YLFALFESKPAIDSSSQQG-QKPDCFSGSLEFRNVSFNYPTRSDVRVLRDLCVKVESGQT 1049
Query: 3154 VALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDC 3333
VA VG SGCGKST + LL+RFY+ +G +++D + + N+ LR Q+ IVSQEP LFDC
Sbjct: 1050 VAFVGSSGCGKSTSVQLLQRFYDPKEGEVLLDDVDAKCFNVQWLRSQMGIVSQEPVLFDC 1109
Query: 3334 TIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIA 3510
+I ENI YG N R V+ EI AAK ANIH+FI GLP Y+T VG KGTQLSGGQKQRIA
Sbjct: 1110 SIAENIAYGDNSRTVSMDEIQSAAKAANIHSFIEGLPLKYETLVGAKGTQLSGGQKQRIA 1169
Query: 3511 IARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAI 3690
IARAL+R+P +LLLDEATSALD ESEK+VQ+ALD A++GRTC++IAHRL+T+QN+D+I +
Sbjct: 1170 IARALIRAPKILLLDEATSALDNESEKVVQQALDQARKGRTCILIAHRLTTVQNADIIVV 1229
Query: 3691 VSEGKIVEKGTHDELIRKSEIYQKFCETQRIV 3786
+++GKI+E G+H EL+ K Y Q I+
Sbjct: 1230 MNKGKIIEHGSHQELLAKCGAYYDLVNAQAII 1261
>gi|27656758|gb|AAO20902.1| Mdr2 [Takifugu rubripes]
Length = 1271
Score = 913 bits (2359), Expect = 0.0
Identities = 522/1300 (40%), Positives = 739/1300 (56%), Gaps = 97/1300 (7%)
Frame = +1
Query: 169 AVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEVVKYCIY 348
A+++G PL+ IV G MT F+ Q + + NP + D + ++ IY
Sbjct: 2 AIVNGLVNPLMCIVFGEMTDSFI--QEAKLSQNHNTSNPRANSTLEAD-----MQRFSIY 54
Query: 349 YLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTARLTD 528
Y +LG + +Y+Q++ + A R ++R+ + I++Q I W+D +TG L RLT+
Sbjct: 55 YSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYDVTETGELNTRLTE 114
Query: 529 -----------------------------DLERVREGLGDKFALLVQMFAAFLAGYGVGF 621
D+ +++EG+GDK LL+Q + F+ + +GF
Sbjct: 115 WVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAASTFITSFVIGF 174
Query: 622 FYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLN 801
+ W +TLV++ +P++ LS A SK + + T EQ YA AGA+A E SSIRTV + +
Sbjct: 175 VHGWKLTLVILAISPVLGLSAALYSKLLTSFTSKEQTAYAKAGAVAAEVLSSIRTVFAFS 234
Query: 802 GHKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFD 981
G ++ + R++ LE R GI K GFS L +Y SYALAFWYG+TL++N
Sbjct: 235 GQRKAIKRYHKNLEDARDMGIKKGVAANTATGFSFLMIYLSYALAFWYGTTLVLNKEYTI 294
Query: 982 RGLI---------------FTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSH 1116
L+ VFF VL G+ +G A P++ SF +ARGAA V +I+
Sbjct: 295 GNLLTNKSVAAETVTTCVQMKVFFVVLYGAYIIGQASPNVQSFASARGAAYKVYNIIDHK 354
Query: 1117 PKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCG 1296
P ID +S +G + +KGDI F+++HF YPSR +I +L +S ++ G IALVGSSGCG
Sbjct: 355 PNIDSFSEDGYKPEYIKGDIVFQNIHFSYPSRPEIKILNDMSFHVRNGQTIALVGSSGCG 414
Query: 1297 KSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGN 1476
KST + LLQRFYDP KG + IDG D+R +N+ LRE IG+VSQEPVLF TI ENI+ G
Sbjct: 415 KSTTIQLLQRFYDPQKGSIFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGR 474
Query: 1477 EHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKIL 1656
T +++ A K +NA DFI LPD + T VG++G QLSGGQKQRIAIARALV+NPKIL
Sbjct: 475 LDVTQEEIERATKESNAYDFIMNLPDKFETLVGDRGTQLSGGQKQRIAIARALVRNPKIL 534
Query: 1657 LLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSH 1836
LLDEATSALD E+E VQ ALD+ + GRTTI++AHRLSTIRN D I F G IVE G+H
Sbjct: 535 LLDEATSALDAESETIVQAALDKVRLGRTTIVIAHRLSTIRNADIIAGFSNGEIVEQGTH 594
Query: 1837 EELMSKQGIFYDMTXXXXXXXXXXEAGKDIEDTISES-------AHSHLXXXXXXXXXXX 1995
+LM +G+++ + D E ++E + S L
Sbjct: 595 SQLMEIKGVYHGLVTMQSFQKLEDLEDSDYEPWVAEKSQLIESFSQSSLQRRRSTRGSLL 654
Query: 1996 XXXXIHQLAEEVEEC---------KAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTP 2148
+ +E EC PP S FK+ ++N + + ++ P
Sbjct: 655 AVSEGTKEEKEKFECDQDNIEEDENVPPVSFFKVMRYNVSEWPYILVGTICAMINGAMQP 714
Query: 2149 VFALVYAEIFNVYSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKL 2328
VF++++ EI + FW F GF C + GE LT+ L
Sbjct: 715 VFSIIFTEI--------------IMFW----------GFQGF-----CFSKSGEILTLNL 745
Query: 2329 RFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALG 2505
R +AF +++RQD+++YD+ ++ G L TR A DA +V+ RL V+ + + ++
Sbjct: 746 RLKAFISMMRQDLSWYDNPKNTVGALTTRLAADAAHVQGAAGVRLAVMTQNFANLGTSII 805
Query: 2506 IGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVH 2685
I F YGW+ + G E+++ G D + LE AGK+A++A+E++RTV
Sbjct: 806 ISFVYGWELTLLILAVVPILAVAGAAEVKLLTGHAAEDKKELEMAGKIATEAIENVRTVV 865
Query: 2686 SLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQA 2865
SL R+ F Y E L P+ + K A YG ++FSQ++IFF+YAA F G+ +
Sbjct: 866 SLTREPTFVALYEENLTVPYKNSQKKAKIYGLTYSFSQAMIFFVYAACFRFGAWLIEAGR 925
Query: 2866 MQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLS-DSGIV 3042
M V+ V + + +G ++ P+ KA+++AS L LI ID+LS + +
Sbjct: 926 MDVEGVFLVVMTMLYGAMAVGEANTYAPNFAKAKISASHLTMLINRQPAIDNLSEEEARL 985
Query: 3043 KPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYN 3222
+ GN+ +V FNYP+R D VLQG L+++ G+T+ALVG SGCGKST + LLERFY+
Sbjct: 986 EKYDGNVLFEDVKFNYPSRPDVPVLQGLNLEVQKGETLALVGSSGCGKSTTIQLLERFYD 1045
Query: 3223 QDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEA 3399
+G +++DG +++ LN+ LR Q+ IVSQEP LFDC++ ENI YG N R+V+ EIV A
Sbjct: 1046 PREGRVLLDGVDVKQLNVHWLRSQIGIVSQEPVLFDCSLAENIAYGDNSRSVSMDEIVAA 1105
Query: 3400 AKMANIHNFILGLP----------------------------------DGYDTHVGEKGT 3477
AK ANIH+FI GLP YDT G+KGT
Sbjct: 1106 AKAANIHSFIEGLPQVAAVNQGKWLIPHLIDSHGAAHDHLHHIQTVSEQRYDTQAGDKGT 1165
Query: 3478 QLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRL 3657
QLSGGQKQR+AIARA++R+P +LLLDEATSALDTESEK+VQEALD A++GRTC+V+AHRL
Sbjct: 1166 QLSGGQKQRVAIARAIIRNPKLLLLDEATSALDTESEKVVQEALDQARKGRTCIVVAHRL 1225
Query: 3658 STIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
STIQN+D IA+ G +VEKGTH +LI K +Y Q
Sbjct: 1226 STIQNADCIAVFQGGVVVEKGTHQQLIAKKGVYHMLVTKQ 1265
>gi|18496818|gb|AAL74250.1| ABC transporter AbcB3 [Dictyostelium
discoideum]
Length = 1432
Score = 894 bits (2311), Expect = 0.0
Identities = 517/1288 (40%), Positives = 743/1288 (57%), Gaps = 65/1288 (5%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F + D +L+ GT+AAVI+GA P +++V G + F Q +D +P
Sbjct: 168 LFRFADNTDKVLMFLGTIAAVINGAAMPTVSLVFGLVVDAFKPTQFND--------DP-- 217
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
+ D +++ V Y L+LG +F SY++ + ER ++R+ YL++ LRQ
Sbjct: 218 ----NYDIYDT-VRSISFYLLMLGGGVFVLSYLETTLWMIAGERQTSRIRREYLESTLRQ 272
Query: 472 QIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVM 651
+I WFD + L++R+ D E +G+K + F+ F+AG+ +GF W +TLV+
Sbjct: 273 EIGWFDTNKANELSSRINSDTVLFEEAIGEKVGRFIHFFSTFVAGFVIGFTKGWQLTLVI 332
Query: 652 MGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFY 831
+PL+ + G +K M T++ QE Y+ AG +AEE SIRTV + +G K +D++
Sbjct: 333 TSVSPLLAIGGFFTAKMMTQMTKLGQEAYSRAGGVAEENIGSIRTVATFSGEKLAIDKYS 392
Query: 832 NALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIIN-------DPTFDRGL 990
N L+ R G + + G+G+GF + +YALAFWYGSTLI N D + G
Sbjct: 393 NNLKDARTVGYKRSFFNGLGLGFVQFVILGTYALAFWYGSTLISNKVTNSVSDRPWTGGD 452
Query: 991 IFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKG 1170
+ +VFFAV+ G+TS+G A P LA F RGAA + +VI+ K +P+S GI + + G
Sbjct: 453 VVSVFFAVIIGATSIGQASPCLALFAQGRGAAYKIFQVIDRQSKANPFSTRGIKPETLSG 512
Query: 1171 DISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGR 1350
+I FKDV F YPSR D+ + G +L++K G + LVG SG GKSTI++LL+RFYDP +G
Sbjct: 513 EIEFKDVGFHYPSRPDVPIFNGFNLKIKPGQTVGLVGDSGGGKSTIISLLERFYDPCQGE 572
Query: 1351 VLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAN 1530
+L+DG D+R+ NV LR++IG+V+QEPVLF TI ENI+ G E AT D++ EA K+ANA+
Sbjct: 573 ILLDGEDIRKFNVRGLRQKIGLVNQEPVLFATTISENIRYGKEGATQDEIEEAAKLANAH 632
Query: 1531 DFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQ 1710
FI +LP GY T VGEKGVQ+SGGQ+QRIAIARA++KNP ILLLDE+TSALD E+ + VQ
Sbjct: 633 SFISQLPQGYNTLVGEKGVQMSGGQRQRIAIARAVIKNPNILLLDESTSALDAESTKLVQ 692
Query: 1711 GALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM----- 1875
ALD GRTTI++AH LSTIRN D I K G VE G+H+ELM+KQG+++D+
Sbjct: 693 EALDVLMKGRTTIVIAHNLSTIRNADVIIYIKKGVAVERGTHDELMAKQGLYFDLVEKQS 752
Query: 1876 -----------TXXXXXXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLA 2022
T E + D+ S S L ++
Sbjct: 753 HQQMYNLLENGTRSRRSSTFSAEV-NPLLDSFHVSKRS-LRKNESESNKKDKEDSNNKKK 810
Query: 2023 EEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLP-A 2199
++ + K M ++ K+N ++G +V P FA+V+ E+ ++ P
Sbjct: 811 KKSNKKKVEEVPMSRVVKYNRPELGLWCFGFLSAVGTGAVYPGFAMVFTEMLTIFQNPDP 870
Query: 2200 DQMQANVYFWCGMFVLMGI-----TFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQD 2364
+ + + F MFV + + FF GF S GE LT +LR + F ++RQD
Sbjct: 871 NYLTDHANFVALMFVALAVGAGISNFFQGFLFSV-----IGEKLTYRLRRDCFAAIMRQD 925
Query: 2365 IAFYDDLRHGTGKLCTRFATDAPNVRYVFT-RLPVVLASIVTICGALGIGFYYGWQXXXX 2541
+ ++D + TGKL + ATDA V+ + + RL +VL +I+T+ G L I FY GWQ
Sbjct: 926 VGWFDLPENSTGKLTSHLATDAALVQGMTSQRLGIVLQNILTMVGGLVIAFYSGWQLTLV 985
Query: 2542 XXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTY 2721
+ +MQ+ G +D AG+VAS+A+ IRTV S ++Q Y
Sbjct: 986 IIACFPLVVITSKVQMQILAGFSSKDG--CGPAGQVASEAISGIRTVASFTTEKQVVELY 1043
Query: 2722 CEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPID------- 2880
+ + P + +K AH G F F+Q ++F +Y +F+ G V D
Sbjct: 1044 KKQQKGPSSEGIKKAHISGFAFGFTQLILFCVYCLSFWYGGKLVGSGVFGATDKEISDNC 1103
Query: 2881 ---------------------------VYRVFFAISFCGQMIGNTTSFIPDVVKARLAAS 2979
+ RVFFAI +G +SF PD+ KA+ AA
Sbjct: 1104 TPQTIPYLWKDYDTCERAQNTIYGFNSMTRVFFAIVMSAIGVGQASSFAPDLAKAKAAAV 1163
Query: 2980 LLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTV 3156
+F L++ P+ ID ++ G + + G+I +N+ F+YPTR D V +GFTL +++G T
Sbjct: 1164 SVFKLLDTPSKIDPTTEDGDRIDIVGGDIEFKNLHFSYPTRPDNSVFRGFTLTLQSGTTT 1223
Query: 3157 ALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCT 3336
ALVG SG GKST + LL+RFYN G I IDG NI+NLN+ LR +V QEPTLF T
Sbjct: 1224 ALVGDSGGGKSTCLSLLQRFYNPVVGEIFIDGHNIKNLNVRHLRHLFGLVGQEPTLFSGT 1283
Query: 3337 IGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIA 3516
I +NI YG + T +EI EA+K++N H+FI+ LP+GY+T +GEK TQLSGGQKQRIAIA
Sbjct: 1284 IADNIRYG-KHDATQEEIEEASKLSNSHSFIIDLPNGYNTELGEKYTQLSGGQKQRIAIA 1342
Query: 3517 RALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVS 3696
RA++R+P +LLLDE+TSALD +S K+VQEAL+ +GRT +VIAH L TIQN+D IA V
Sbjct: 1343 RAIIRNPKILLLDESTSALDADSTKLVQEALENVMKGRTTIVIAHNLLTIQNADCIAYVR 1402
Query: 3697 EGKIVEKGTHDELIRKSEIYQKFCETQR 3780
G+I+E+GTHDEL+ Y + Q+
Sbjct: 1403 AGQIIERGTHDELLEAEGPYSQLWYNQQ 1430
>gi|4704820|gb|AAD28285.1| bile salt export pump [Homo sapiens]
Length = 1321
Score = 885 bits (2286), Expect = 0.0
Identities = 483/1275 (37%), Positives = 741/1275 (57%), Gaps = 47/1275 (3%)
Frame = +1
Query: 91 VKLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFL----------- 237
V++ + +F ++ D+ L+ G++ A +HG P + ++ G MT VF+
Sbjct: 43 VRVGFFQLFRFSSSTDIWLMFVGSLCAFLHGIAQPGVLLIFGTMTDVFIDYDVELQELQI 102
Query: 238 --RAQNSDFVVGVD---NVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIAC 402
+A ++ +V + N N L SE++K+ YY + V + T Y+QI
Sbjct: 103 PGKACVNNTIVWTNSSLNQNMTNGTRCGLLNIESEMIKFASYYAGIAVAVLITGYIQICF 162
Query: 403 FESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQ 582
+ A R + K+R+ Y + I+R +I WFD G L R +DD+ ++ + + D+ AL +Q
Sbjct: 163 WVIAAARQIQKMRKFYFRRIMRMEIGWFDCNSVGELNTRFSDDINKINDAIADQMALFIQ 222
Query: 583 MFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAE 762
+ + G+ +GFF W +TLV++ +PLI + A + S++ T E + YA AG +A+
Sbjct: 223 RMTSTICGFLLGFFRGWKLTLVIISVSPLIGIGAATIGLSVSKFTDYELKAYAKAGVVAD 282
Query: 763 ETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFW 942
E SS+RTV + G KRE++R+ L ++ GI K MG GF ++ YALAFW
Sbjct: 283 EVISSMRTVAAFGGEKREVERYEKNLVFAQRWGIRKGIVMGFFTGFVWCLIFLCYALAFW 342
Query: 943 YGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPK 1122
YGSTL++++ + G + +F +V+ G+ +LG A P L +F T R AA+++ I+ P
Sbjct: 343 YGSTLVLDEGEYTPGTLVQIFLSVIVGALNLGNASPCLEAFATGRAAATSIFETIDRKPI 402
Query: 1123 IDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKS 1302
ID S +G +D +KG+I F +V F YPSR ++ +L +++ +K G+ ALVG SG GKS
Sbjct: 403 IDCMSEDGYKLDRIKGEIEFHNVTFHYPSRPEVKILNDLNMAIKPGEMTALVGPSGAGKS 462
Query: 1303 TIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEH 1482
T + L+QRFYDP +G V +DG D+R +N+ LR+QIGIV QEPVLF TI ENI+ G E
Sbjct: 463 TALQLIQRFYDPCEGMVTVDGHDIRSLNIQWLRDQIGIVEQEPVLFSTTIAENIRYGRED 522
Query: 1483 ATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLL 1662
AT + +V+A K ANA +FI LP + T VGE G Q+SGGQKQR+AIARAL++NPKILLL
Sbjct: 523 ATMEDIVQAAKEANAYNFIMDLPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILLL 582
Query: 1663 DEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEE 1842
D ATSALD E+E VQ L + Q G T I VAHRLST+R D I F+ G VE G+HEE
Sbjct: 583 DMATSALDNESEAMVQEVLSKIQHGHTIISVAHRLSTVRAADTIIGFEHGTAVERGTHEE 642
Query: 1843 LMSKQGIFYDMTXXXXXXXXXXEAGKDIEDTISE----------SAHSHLXXXXXXXXXX 1992
L+ ++G+++ + +DI+D + S L
Sbjct: 643 LLERKGVYFTLVTLQSQGNQALNE-EDIKDATEDDMLARTFSRGSYQDSLRASIRQRSKS 701
Query: 1993 XXXXXIHQLAEEVEECKA-----------------PPTSMFKIFKFNGDKVGWXXXXXXX 2121
+H+ V + K+ P + +I KF+ + +
Sbjct: 702 QLSYLVHEPPLAVVDHKSTYEEDRKDKDIPVQEEVEPAPVRRILKFSAPEWPYMLVGSVG 761
Query: 2122 XXXXXSVTPVFALVYAEIFNVYSLP-ADQMQANVYFWCGMFVLMGITFFVGFFTSANCLG 2298
+VTP++A ++++I +S+P ++ ++ + C +FV MG F
Sbjct: 762 AAVNGTVTPLYAFLFSQILGTFSIPDKEEQRSQINGVCLLFVAMGCVSLFTQFLQGYAFA 821
Query: 2299 RCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLA 2475
+ GE LT +LR F+ +L QDIA++DDLR+ G L TR ATDA V+ +++ +++
Sbjct: 822 KSGELLTKRLRKFGFRAMLGQDIAWFDDLRNSPGALTTRLATDASQVQGAAGSQIGMIVN 881
Query: 2476 SIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVAS 2655
S + A+ I F + W+ + G + +M G RD Q LE G++ +
Sbjct: 882 SFTNVTVAMIIAFSFSWKLSLVILCFFPFLALSGATQTRMLTGFASRDKQALEMVGQITN 941
Query: 2656 QAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFY 2835
+A+ +IRTV + ++ +F L +PF T ++ A+ YG FAF+Q ++F +A++
Sbjct: 942 EALSNIRTVAGIGKERRFIEALETELEKPFKTAIQKANIYGFCFAFAQCIMFIANSASYR 1001
Query: 2836 LGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPI 3015
G ++ + + V+RV A+ +G S+ P KA+++A+ F L++ PI
Sbjct: 1002 YGGYLISNEGLHFSYVFRVISAVVLSATALGRAFSYTPSYAKAKISAARFFQLLDRQPPI 1061
Query: 3016 DSLSDSGIV-KPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKST 3192
+ +G G I + F YP+R D++VL G ++ I G+T+A VG SGCGKST
Sbjct: 1062 SVYNTAGEKWDNFQGKIDFVDCKFTYPSRPDSQVLNGLSVSISPGQTLAFVGSSGCGKST 1121
Query: 3193 IMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTN-R 3369
+ LLERFY+ D+G +MIDG + + +N+ LR + IVSQEP LF C+I +NI YG N +
Sbjct: 1122 SIQLLERFYDPDQGKVMIDGHDSKKVNVQFLRSNIGIVSQEPVLFACSIMDNIKYGDNTK 1181
Query: 3370 NVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLL 3549
+ + ++ AAK A +H+F++ LP+ Y+T+VG +G+QLS G+KQRIAIARA+VR P +LL
Sbjct: 1182 EIPMERVIAAAKQAQLHDFVMSLPEKYETNVGSQGSQLSRGEKQRIAIARAIVRDPKILL 1241
Query: 3550 LDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHD 3729
LDEATSALDTESEK VQ ALD A++GRTC+VIAHRLSTIQN+D+IA++++G ++EKGTH+
Sbjct: 1242 LDEATSALDTESEKTVQVALDKAREGRTCIVIAHRLSTIQNADIIAVMAQGVVIEKGTHE 1301
Query: 3730 ELIRKSEIYQKFCET 3774
EL+ + Y K T
Sbjct: 1302 ELMAQKGAYYKLVTT 1316
>gi|21536378|ref|NP_003733.2| ATP-binding cassette, sub-family B
(MDR/TAP), member 11; ABC member 16, MDR/TAP subfamily;
progressive familial intrahepatic cholestasis 2; bile
salt export pump [Homo sapiens]
Length = 1321
Score = 884 bits (2285), Expect = 0.0
Identities = 483/1275 (37%), Positives = 741/1275 (57%), Gaps = 47/1275 (3%)
Frame = +1
Query: 91 VKLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFL----------- 237
V++ + +F ++ D+ L+ G++ A +HG P + ++ G MT VF+
Sbjct: 43 VRVGFFQLFRFSSSTDIWLMFVGSLCAFLHGIAQPGVLLIFGTMTDVFIDYDVELQELQI 102
Query: 238 --RAQNSDFVVGVD---NVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIAC 402
+A ++ +V + N N L SE++K+ YY + V + T Y+QI
Sbjct: 103 PGKACVNNTIVWTNSSLNQNMTNGTRCGLLNIESEMIKFASYYAGIAVAVLITGYIQICF 162
Query: 403 FESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQ 582
+ A R + K+R+ Y + I+R +I WFD G L R +DD+ ++ + + D+ AL +Q
Sbjct: 163 WVIAAARQIQKMRKFYFRRIMRMEIGWFDCNSVGELNTRFSDDINKINDAIADQMALFIQ 222
Query: 583 MFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAE 762
+ + G+ +GFF W +TLV++ +PLI + A + S++ T E + YA AG +A+
Sbjct: 223 RMTSTICGFLLGFFRGWKLTLVIISVSPLIGIGAATIGLSVSKFTDYELKAYAKAGVVAD 282
Query: 763 ETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFW 942
E SS+RTV + G KRE++R+ L ++ GI K MG GF ++ YALAFW
Sbjct: 283 EVISSMRTVAAFGGEKREVERYEKNLVFAQRWGIRKGIVMGFFTGFVWCLIFLCYALAFW 342
Query: 943 YGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPK 1122
YGSTL++++ + G + +F +V+ G+ +LG A P L +F T R AA+++ I+ P
Sbjct: 343 YGSTLVLDEGEYTPGTLVQIFLSVIVGALNLGNASPCLEAFATGRAAATSIFETIDRKPI 402
Query: 1123 IDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKS 1302
ID S +G +D +KG+I F +V F YPSR ++ +L +++ +K G+ ALVG SG GKS
Sbjct: 403 IDCMSEDGYKLDRIKGEIEFHNVTFHYPSRPEVKILNDLNMVIKPGEMTALVGPSGAGKS 462
Query: 1303 TIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEH 1482
T + L+QRFYDP +G V +DG D+R +N+ LR+QIGIV QEPVLF TI ENI+ G E
Sbjct: 463 TALQLIQRFYDPCEGMVTVDGHDIRSLNIQWLRDQIGIVEQEPVLFSTTIAENIRYGRED 522
Query: 1483 ATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLL 1662
AT + +V+A K ANA +FI LP + T VGE G Q+SGGQKQR+AIARAL++NPKILLL
Sbjct: 523 ATMEDIVQAAKEANAYNFIMDLPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILLL 582
Query: 1663 DEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEE 1842
D ATSALD E+E VQ L + Q G T I VAHRLST+R D I F+ G VE G+HEE
Sbjct: 583 DMATSALDNESEAMVQEVLSKIQHGHTIISVAHRLSTVRAADTIIGFEHGTAVERGTHEE 642
Query: 1843 LMSKQGIFYDMTXXXXXXXXXXEAGKDIEDTISE----------SAHSHLXXXXXXXXXX 1992
L+ ++G+++ + +DI+D + S L
Sbjct: 643 LLERKGVYFTLVTLQSQGNQALNE-EDIKDATEDDMLARTFSRGSYQDSLRASIRQRSKS 701
Query: 1993 XXXXXIHQLAEEVEECKA-----------------PPTSMFKIFKFNGDKVGWXXXXXXX 2121
+H+ V + K+ P + +I KF+ + +
Sbjct: 702 QLSYLVHEPPLAVVDHKSTYEEDRKDKDIPVQEEVEPAPVRRILKFSAPEWPYMLVGSVG 761
Query: 2122 XXXXXSVTPVFALVYAEIFNVYSLP-ADQMQANVYFWCGMFVLMGITFFVGFFTSANCLG 2298
+VTP++A ++++I +S+P ++ ++ + C +FV MG F
Sbjct: 762 AAVNGTVTPLYAFLFSQILGTFSIPDKEEQRSQINGVCLLFVAMGCVSLFTQFLQGYAFA 821
Query: 2299 RCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLA 2475
+ GE LT +LR F+ +L QDIA++DDLR+ G L TR ATDA V+ +++ +++
Sbjct: 822 KSGELLTKRLRKFGFRAMLGQDIAWFDDLRNSPGALTTRLATDASQVQGAAGSQIGMIVN 881
Query: 2476 SIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVAS 2655
S + A+ I F + W+ + G + +M G RD Q LE G++ +
Sbjct: 882 SFTNVTVAMIIAFSFSWKLSLVILCFFPFLALSGATQTRMLTGFASRDKQALEMVGQITN 941
Query: 2656 QAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFY 2835
+A+ +IRTV + ++ +F L +PF T ++ A+ YG FAF+Q ++F +A++
Sbjct: 942 EALSNIRTVAGIGKERRFIEALETELEKPFKTAIQKANIYGFCFAFAQCIMFIANSASYR 1001
Query: 2836 LGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPI 3015
G ++ + + V+RV A+ +G S+ P KA+++A+ F L++ PI
Sbjct: 1002 YGGYLISNEGLHFSYVFRVISAVVLSATALGRAFSYTPSYAKAKISAARFFQLLDRQPPI 1061
Query: 3016 DSLSDSGIV-KPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKST 3192
+ +G G I + F YP+R D++VL G ++ I G+T+A VG SGCGKST
Sbjct: 1062 SVYNTAGEKWDNFQGKIDFVDCKFTYPSRPDSQVLNGLSVSISPGQTLAFVGSSGCGKST 1121
Query: 3193 IMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTN-R 3369
+ LLERFY+ D+G +MIDG + + +N+ LR + IVSQEP LF C+I +NI YG N +
Sbjct: 1122 SIQLLERFYDPDQGKVMIDGHDSKKVNVQFLRSNIGIVSQEPVLFACSIMDNIKYGDNTK 1181
Query: 3370 NVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLL 3549
+ + ++ AAK A +H+F++ LP+ Y+T+VG +G+QLS G+KQRIAIARA+VR P +LL
Sbjct: 1182 EIPMERVIAAAKQAQLHDFVMSLPEKYETNVGSQGSQLSRGEKQRIAIARAIVRDPKILL 1241
Query: 3550 LDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHD 3729
LDEATSALDTESEK VQ ALD A++GRTC+VIAHRLSTIQN+D+IA++++G ++EKGTH+
Sbjct: 1242 LDEATSALDTESEKTVQVALDKAREGRTCIVIAHRLSTIQNADIIAVMAQGVVIEKGTHE 1301
Query: 3730 ELIRKSEIYQKFCET 3774
EL+ + Y K T
Sbjct: 1302 ELMAQKGAYYKLVTT 1316
>gi|14030565|gb|AAK52958.1| bile salt export pump [Raja erinacea]
Length = 1348
Score = 884 bits (2285), Expect = 0.0
Identities = 503/1284 (39%), Positives = 737/1284 (57%), Gaps = 56/1284 (4%)
Frame = +1
Query: 91 VKLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFL----------- 237
+K+ + +F + ++ L++ G V A++HG P + +V G +T F+
Sbjct: 60 IKIGFFQLFRFASCYEVTLMVFGGVCALLHGVAQPAVLLVFGLLTDTFIAYDIELQELKD 119
Query: 238 ---RAQNSD--FVVGVDNVNPEG-LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIA 399
N+ +V G + +N + + E+ + YY+ +G + Y QI
Sbjct: 120 TRKHCDNNTIHWVNGSEYLNQHNETMSCGILNIEKEMTMFAYYYVGIGCSVLLLGYFQIC 179
Query: 400 CFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLV 579
+ + A R K+R+ Y + I+R ++ WFD G L R++DD+ ++ + + D+ + +
Sbjct: 180 FWVTAAARQTQKIRKAYFRQIMRMEMGWFDCNSVGELNTRMSDDINKINDAIADQVGIFI 239
Query: 580 QMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIA 759
Q F+ F++G+ +GF W +TLV++ +PLI L A M+ S+A T + + YA AGA+A
Sbjct: 240 QRFSTFVSGFLMGFVNGWKLTLVIIAVSPLIGLGAALMALSVARLTGLGLKAYAKAGAVA 299
Query: 760 EETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAF 939
+E SSIRTV + +G K+E+DR+ L ++ GI K MG G+ + ++ YALAF
Sbjct: 300 DEVLSSIRTVAAFSGEKKEVDRYDRNLVFAQRWGIRKGMIMGFFTGYVWMIIFCCYALAF 359
Query: 940 WYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHP 1119
WYGS L+I + G + VF VL + +LG A P L +F + RGAA + I+ P
Sbjct: 360 WYGSKLVIEQNEYTPGGLLQVFLGVLVAAMNLGQASPCLEAFASGRGAAVKIFETIDREP 419
Query: 1120 KIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGK 1299
+ID S G ++ +KGDI F +V F YPSR D+ L +S+ +KAG+ A VG SG GK
Sbjct: 420 EIDCMSEGGYTLNKVKGDIEFHNVTFNYPSRPDVKTLDRLSMVIKAGETTAFVGPSGSGK 479
Query: 1300 STIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNE 1479
ST V L+QRFYDP +G V +DG D+R +N+ LR IGIV QEPVLF TI ENI+ E
Sbjct: 480 STAVELIQRFYDPKQGMVTLDGHDIRSLNIQWLRSLIGIVEQEPVLFSTTIEENIRYVRE 539
Query: 1480 HATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILL 1659
T + +V+A K ANA DFI LP+ + T VGE G Q+SGGQKQRIAIARALV+NPKILL
Sbjct: 540 GLTKNDIVQAAKEANAYDFIMDLPEKFNTLVGEGGGQMSGGQKQRIAIARALVRNPKILL 599
Query: 1660 LDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHE 1839
LD ATSALD E+E VQGALD+ + GRTTI +AHRLST+RNVD I F+ G VE G H
Sbjct: 600 LDMATSALDNESEAIVQGALDKVRFGRTTISIAHRLSTVRNVDVIIGFEHGRAVERGRHA 659
Query: 1840 ELMSKQGIFYDM-TXXXXXXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQ 2016
EL+ ++GI++ + T E + + I + A HQ
Sbjct: 660 ELLERKGIYFTLVTLQTQGEQALHEKARQVNGAIEDGASEKRQLIRRGSSRASVRSTRHQ 719
Query: 2017 LAE----------------------------------EVEECKAPPTSMFKIFKFNGDKV 2094
+ E EE P + +I K+N +
Sbjct: 720 RSRSQVSEVLSDLSGPGDVASAVRTPSISLGDEDKDVEEEEESIEPAPVSRILKYNVSEW 779
Query: 2095 GWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQAN-VYFWCGMFVLMGITFFVG 2271
+ V P++AL++++I +SL ++ + N + C FV++G+ F+
Sbjct: 780 PYMLFGSLGAAVNGGVNPIYALLFSQILGTFSLQNEEEKINQINAICLFFVVVGLVSFLT 839
Query: 2272 FFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVR-YV 2448
F + + GE LT +LR F+ +LRQ+I ++DD ++ G L TR ATDA V+
Sbjct: 840 QFLQSYFFAKSGELLTRRLRKLGFQAMLRQEIGWFDDRKNSPGTLTTRLATDASQVQGAT 899
Query: 2449 FTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQL 2628
T++ +++ SI I +L I FY+ W+ + G + +M G +D +
Sbjct: 900 GTQIGMIVNSITNIGVSLIIAFYFSWKLTLVILCFLPFLALTGALQARMLTGFANQDKEA 959
Query: 2629 LEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLI 2808
LE AG+++S+A+ +IRT+ L +++ F + L P+ +K A+ YG F F+QS+I
Sbjct: 960 LEAAGQISSEALSNIRTIAGLAKEKMFVQLFEAQLEAPYKAAIKKANVYGLCFGFAQSVI 1019
Query: 2809 FFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLF 2988
F AA++ G V + + V+RV AI G +G +S+ PD KA++AA+ F
Sbjct: 1020 FLANAASYRFGGYLVVAENLHFSIVFRVISAIVTSGTALGRASSYTPDYAKAKIAAARFF 1079
Query: 2989 YLIEHPTPIDSLSDSGIV-KPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALV 3165
LI+ I+ S G G+I F YPTR D +VL G ++ + G+T+A V
Sbjct: 1080 QLIDRAPKINIDSSEGEKWSNFRGDIKFVECTFTYPTRPDFQVLNGLSVCVMPGQTLAFV 1139
Query: 3166 GHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGE 3345
G SGCGKST + LLERFY+ ++G ++IDG + N+N + LR ++ IVSQEP LFD +I E
Sbjct: 1140 GSSGCGKSTSVQLLERFYDPNQGRVIIDGRSTTNVNTAFLRSKIGIVSQEPVLFDSSIEE 1199
Query: 3346 NICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARA 3522
NI YG N R V+ E++ AAK A +H+F++ LP+ Y T VG +G+QLS GQKQRIAIARA
Sbjct: 1200 NIKYGDNSRQVSMDEVIAAAKKAQLHSFVMSLPEKYGTRVGAQGSQLSRGQKQRIAIARA 1259
Query: 3523 LVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEG 3702
+VR P +LLLDEATSALDTESEKIVQ+ALD A++GRTC+VIAHRLSTIQNSD+IA++S G
Sbjct: 1260 IVRDPKILLLDEATSALDTESEKIVQDALDEARKGRTCIVIAHRLSTIQNSDIIAVMSRG 1319
Query: 3703 KIVEKGTHDELIRKSEIYQKFCET 3774
I+E+G+H L+ Y K T
Sbjct: 1320 IIIEQGSHGNLMAAKGAYYKLVTT 1343
>gi|38073917|ref|XP_283101.2| similar to multidrug resistance
p-glycoprotein [Mus musculus]
Length = 1214
Score = 884 bits (2284), Expect = 0.0
Identities = 494/1148 (43%), Positives = 682/1148 (59%), Gaps = 8/1148 (0%)
Frame = +1
Query: 343 IYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTARL 522
+YY+ +G YVQI+ + A R ++R+ + +IL Q I WFD L R+
Sbjct: 68 LYYIGIGAAALIFGYVQISFWVITAARQTTRIRKQFFHSILAQDISWFDGSDICELNTRM 127
Query: 523 TDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKS 702
T D+ ++ +G+GDK L+ Q + F G + SW ++LV++ +PLI+ S A S+
Sbjct: 128 TGDINKLCDGIGDKIPLMFQNISGFSIGLVISLIKSWKLSLVVLSTSPLIMASSALCSRM 187
Query: 703 MATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYM 882
+ + T E + Y+ AGA+AEE SSI+TV + ++E+ R+ L+ + GI +
Sbjct: 188 IISLTSKELDAYSKAGAVAEEALSSIQTVTAFGAQEKEIQRYTQHLKDAKDAGIKRATAS 247
Query: 883 GIGVGFSNLCMYSSYALAFWYGSTLIIN-DPTFDRGLIFTVFFAVLSGSTSLGGALPHLA 1059
+ +G M +Y LAFWYG++LI +P + G I VFF+V+ S +G PHL
Sbjct: 248 KLSLGAVYFFMNGAYGLAFWYGTSLIFGGEPGYTIGTILAVFFSVIHSSYCIGSVAPHLE 307
Query: 1060 SFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGI 1239
+F ARGAA + +VI+ P ID +S G + + ++G+I FK+V F YPSR VLKG+
Sbjct: 308 TFTVARGAAFNIFQVIDKKPNIDNFSTAGFVPECIEGNIEFKNVSFSYPSRPSAKVLKGL 367
Query: 1240 SLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIV 1419
+L++KAG+ +ALVG SG GKST V LLQR YDP G + +D D+R NV REQIG+V
Sbjct: 368 NLKIKAGETVALVGPSGSGKSTTVQLLQRLYDPEDGCITVDENDIRAQNVRHYREQIGVV 427
Query: 1420 SQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSG 1599
QEPVLF TI NIK G E ++ +A + ANA DFI P + T VGEKG Q+SG
Sbjct: 428 RQEPVLFGTTIGNNIKFGREGVGEKEMEQAAREANAYDFIMAFPKKFNTLVGEKGAQMSG 487
Query: 1600 GQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIR 1779
GQKQRIAIARALV+NPKIL+LDEATSALDTE+E VQ AL++A GRTTI+VAHRLSTIR
Sbjct: 488 GQKQRIAIARALVRNPKILILDEATSALDTESESLVQTALEKASKGRTTIVVAHRLSTIR 547
Query: 1780 NVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXXEAGKDIEDTISESAHSH 1959
D I K G +VE G+H ELM+KQG++Y + + T +++
Sbjct: 548 GADLIVTMKDGMVVEKGTHAELMAKQGLYYSLAMAQDIKKVDEQMESRTCSTAGNASYGS 607
Query: 1960 LXXXXXXXXXXXXXXXIHQLAEEVEECKA--PPTSMFKIFKFNGDKVGWXXXXXXXXXXX 2133
L QL E V K P S+ KIFK + + +
Sbjct: 608 LCDVNSAKAPCT-----DQLEEAVHHQKTSLPEVSLLKIFKLSKSEWPFVVLGTLASALN 662
Query: 2134 XSVTPVFALVYAEIFNVY-SLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGE 2310
SV PVF++++ ++ ++ ++ + + M V++GI V + GR E
Sbjct: 663 GSVHPVFSIIFGKLVTMFEDKNKATLKQDAELYSMMLVVLGIVALVTYLMQGLFYGRAEE 722
Query: 2311 SLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVFT-RLPVVLASIVT 2487
+L M+LR AFK +L QD+A+YDD + TG L T A D ++ T RL +V +
Sbjct: 723 NLAMRLRHSAFKAMLYQDMAWYDDKENNTGALTTTLAVDVAQIQGAATSRLGIVTQDVSN 782
Query: 2488 ICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVE 2667
+ ++ I F YGW+ + G + G RD Q L+ AGK+A++AVE
Sbjct: 783 MSLSILISFIYGWEMTLLILSFAPVLAVTGMIQTAAMAGFANRDKQALKRAGKIATEAVE 842
Query: 2668 HIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSI 2847
+IRTV SL R+ F Y E L+ LK AH G +A S + + F +AA F G+
Sbjct: 843 NIRTVVSLTRERAFEQMYEETLQTQHRNALKRAHITGCCYAVSHAFVHFAHAAGFRFGAY 902
Query: 2848 FVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLS 3027
+ M P ++ VF AI++ IG T + P+ KA+ AS LF L+++ I+S S
Sbjct: 903 LIQAGRMMPEGMFIVFTAIAYGAMAIGETLVWAPEYSKAKAGASHLFALLKNKPTINSCS 962
Query: 3028 DSGIVKPIT--GNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMG 3201
SG KP T GN+ R V F YP R + VLQ +L I+ GKTVA VG SGCGKST +
Sbjct: 963 QSG-EKPDTCEGNLEFREVSFVYPCRPEVPVLQNMSLSIEKGKTVAFVGSSGCGKSTCVQ 1021
Query: 3202 LLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTN-RNVT 3378
LL+RFY+ KG +++DG +++ LN+ LR Q IVSQEP LF+C+I ENI YG N R V
Sbjct: 1022 LLQRFYDPMKGQVLLDGVDVKELNVQWLRSQTAIVSQEPVLFNCSIAENIAYGDNSRMVP 1081
Query: 3379 YQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDE 3558
+EI E A ANIH+FI GLP Y+T VG +G QLSGGQKQR+AIARAL+R P +LLLDE
Sbjct: 1082 LEEIKEVADAANIHSFIEGLPRKYNTLVGLRGVQLSGGQKQRLAIARALLRKPKILLLDE 1141
Query: 3559 ATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELI 3738
ATSALD ESEK+VQ+ALD A++G+TCLV+AHRLSTIQN+D+I ++ G I E+GTH EL+
Sbjct: 1142 ATSALDNESEKVVQQALDKARRGKTCLVVAHRLSTIQNADMIVVLQNGSIKEQGTHQELL 1201
Query: 3739 RKSEIYQK 3762
R + Y K
Sbjct: 1202 RNGDTYFK 1209
Score = 367 bits (941), Expect = 2e-99
Identities = 212/580 (36%), Positives = 332/580 (56%), Gaps = 4/580 (0%)
Frame = +1
Query: 148 LITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSE 327
++ GT+A+ ++G+ P+ +I+ G + T+F ++ N L +
Sbjct: 652 VVLGTLASALNGSVHPVFSIIFGKLVTMF------------EDKNKATL--------KQD 691
Query: 328 VVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQ--T 501
Y + +VLG++ T +Q + E L +LR + KA+L Q + W+D ++ T
Sbjct: 692 AELYSMMLVVLGIVALVTYLMQGLFYGRAEENLAMRLRHSAFKAMLYQDMAWYDDKENNT 751
Query: 502 GNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLS 681
G LT L D+ +++ + ++ Q + + F Y W MTL+++ FAP++ ++
Sbjct: 752 GALTTTLAVDVAQIQGAATSRLGIVTQDVSNMSLSILISFIYGWEMTLLILSFAPVLAVT 811
Query: 682 GAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTG 861
G + +MA +++ AG IA E +IRTV SL + + L+ +
Sbjct: 812 GMIQTAAMAGFANRDKQALKRAGKIATEAVENIRTVVSLTRERAFEQMYEETLQTQHRNA 871
Query: 862 IVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGG 1041
+ + G S+ ++ ++A F +G+ LI G+ F VF A+ G+ ++G
Sbjct: 872 LKRAHITGCCYAVSHAFVHFAHAAGFRFGAYLIQAGRMMPEGM-FIVFTAIAYGAMAIGE 930
Query: 1042 ALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDI 1221
L + A+ AS + ++ + P I+ S G D +G++ F++V F YP R ++
Sbjct: 931 TLVWAPEYSKAKAGASHLFALLKNKPTINSCSQSGEKPDTCEGNLEFREVSFVYPCRPEV 990
Query: 1222 HVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLR 1401
VL+ +SL ++ G +A VGSSGCGKST V LLQRFYDP KG+VL+DGVD++E+NV LR
Sbjct: 991 PVLQNMSLSIEKGKTVAFVGSSGCGKSTCVQLLQRFYDPMKGQVLLDGVDVKELNVQWLR 1050
Query: 1402 EQIGIVSQEPVLFDGTIYENIKMGNEH--ATHDQVVEACKMANANDFIKRLPDGYGTRVG 1575
Q IVSQEPVLF+ +I ENI G+ +++ E AN + FI+ LP Y T VG
Sbjct: 1051 SQTAIVSQEPVLFNCSIAENIAYGDNSRMVPLEEIKEVADAANIHSFIEGLPRKYNTLVG 1110
Query: 1576 EKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIV 1755
+GVQLSGGQKQR+AIARAL++ PKILLLDEATSALD E+E+ VQ ALD+A+ G+T ++V
Sbjct: 1111 LRGVQLSGGQKQRLAIARALLRKPKILLLDEATSALDNESEKVVQQALDKARRGKTCLVV 1170
Query: 1756 AHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM 1875
AHRLSTI+N D I V + G+I E G+H+EL+ ++ +
Sbjct: 1171 AHRLSTIQNADMIVVLQNGSIKEQGTHQELLRNGDTYFKL 1210
Score = 310 bits (795), Expect = 1e-82
Identities = 192/497 (38%), Positives = 281/497 (55%), Gaps = 8/497 (1%)
Frame = +1
Query: 2317 TMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNV-RYVFTRLPVVLASIVTIC 2493
T ++R + F ++L QDI+++D +L TR D + + ++P++ +I
Sbjct: 96 TTRIRKQFFHSILAQDISWFDG--SDICELNTRMTGDINKLCDGIGDKIPLMFQNISGFS 153
Query: 2494 GALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHI 2673
L I W+ +M ++ +AG VA +A+ I
Sbjct: 154 IGLVISLIKSWKLSLVVLSTSPLIMASSALCSRMIISLTSKELDAYSKAGAVAEEALSSI 213
Query: 2674 RTVHSLNRQEQFHFTYCEYLREPFNTNLKHAH----TYGAVFAFSQSLIFFMYAAAFYLG 2841
+TV + QE+ Y ++L++ + +K A + GAV+ F Y AF+ G
Sbjct: 214 QTVTAFGAQEKEIQRYTQHLKDAKDAGIKRATASKLSLGAVYFFMNGA----YGLAFWYG 269
Query: 2842 S--IFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPI 3015
+ IF + + VFF++ IG+ + AR AA +F +I+ I
Sbjct: 270 TSLIFGGEPGYTIGTILAVFFSVIHSSYCIGSVAPHLETFTVARGAAFNIFQVIDKKPNI 329
Query: 3016 DSLSDSGIVKP-ITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKST 3192
D+ S +G V I GNI +NV F+YP+R KVL+G L IKAG+TVALVG SG GKST
Sbjct: 330 DNFSTAGFVPECIEGNIEFKNVSFSYPSRPSAKVLKGLNLKIKAGETVALVGPSGSGKST 389
Query: 3193 IMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRN 3372
+ LL+R Y+ + G I +D ++IR N+ REQ+ +V QEP LF TIG NI +G
Sbjct: 390 TVQLLQRLYDPEDGCITVDENDIRAQNVRHYREQIGVVRQEPVLFGTTIGNNIKFG-REG 448
Query: 3373 VTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLL 3552
V +E+ +AA+ AN ++FI+ P ++T VGEKG Q+SGGQKQRIAIARALVR+P +L+L
Sbjct: 449 VGEKEMEQAAREANAYDFIMAFPKKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILIL 508
Query: 3553 DEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDE 3732
DEATSALDTESE +VQ AL+ A +GRT +V+AHRLSTI+ +D+I + +G +VEKGTH E
Sbjct: 509 DEATSALDTESESLVQTALEKASKGRTTIVVAHRLSTIRGADLIVTMKDGMVVEKGTHAE 568
Query: 3733 LIRKSEIYQKFCETQRI 3783
L+ K +Y Q I
Sbjct: 569 LMAKQGLYYSLAMAQDI 585
>gi|12643301|sp|O95342|AB11_HUMAN Bile salt export pump (ATP-binding
cassette, sub-family B, member 11)
gi|3873243|gb|AAC77455.1| bile salt export pump [Homo sapiens]
Length = 1321
Score = 883 bits (2282), Expect = 0.0
Identities = 482/1275 (37%), Positives = 741/1275 (57%), Gaps = 47/1275 (3%)
Frame = +1
Query: 91 VKLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFL----------- 237
V++ + +F ++ D+ L+ G++ A +HG P + ++ G MT VF+
Sbjct: 43 VRVGFFQLFRFSSSTDIWLMFVGSLCAFLHGIAQPGVLLIFGTMTDVFIDYDVELQELQI 102
Query: 238 --RAQNSDFVVGVD---NVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIAC 402
+A ++ +V + N N L SE++K+ YY + V + T Y+QI
Sbjct: 103 PGKACVNNTIVWTNSSLNQNMTNGTRCGLLNIESEMIKFASYYAGIAVAVLITGYIQICF 162
Query: 403 FESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQ 582
+ A R + K+R+ Y + I+R +I WFD G L R +DD+ ++ + + D+ AL +Q
Sbjct: 163 WVIAAARQIQKMRKFYFRRIMRMEIGWFDCNSVGELNTRFSDDINKINDAIADQMALFIQ 222
Query: 583 MFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAE 762
+ + G+ +GFF W +TLV++ +PLI + A + S++ T E + YA AG +A+
Sbjct: 223 RMTSTICGFLLGFFRGWKLTLVIISVSPLIGIGAATIGLSVSKFTDYELKAYAKAGVVAD 282
Query: 763 ETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFW 942
E SS+RTV + G KRE++R+ L ++ GI K MG GF ++ YA+AFW
Sbjct: 283 EVISSMRTVAAFGGEKREVERYEKNLVFAQRWGIRKGIVMGFFTGFVWCLIFLCYAVAFW 342
Query: 943 YGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPK 1122
YGSTL++++ + G + +F +V+ G+ +LG A P L +F T R AA+++ I+ P
Sbjct: 343 YGSTLVLDEGEYTPGTLVQIFLSVIVGALNLGNASPCLEAFATGRAAATSIFETIDRKPI 402
Query: 1123 IDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKS 1302
ID S +G +D +KG+I F +V F YPSR ++ +L +++ +K G+ ALVG SG GKS
Sbjct: 403 IDCMSEDGYKLDRIKGEIEFHNVTFHYPSRPEVKILNDLNMVIKPGEMTALVGPSGAGKS 462
Query: 1303 TIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEH 1482
T + L+QRFYDP +G V +DG D+R +N+ LR+QIGIV QEPVLF TI ENI+ G E
Sbjct: 463 TALQLIQRFYDPCEGMVTVDGHDIRSLNIQWLRDQIGIVEQEPVLFSTTIAENIRYGRED 522
Query: 1483 ATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLL 1662
AT + +V+A K ANA +FI LP + T VGE G Q+SGGQKQR+AIARAL++NPKILLL
Sbjct: 523 ATMEDIVQAAKEANAYNFIMDLPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILLL 582
Query: 1663 DEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEE 1842
D ATSALD E+E VQ L + Q G T I VAHRLST+R D I F+ G VE G+HEE
Sbjct: 583 DMATSALDNESEAMVQEVLSKIQHGHTIISVAHRLSTVRAADTIIGFEHGTAVERGTHEE 642
Query: 1843 LMSKQGIFYDMTXXXXXXXXXXEAGKDIEDTISE----------SAHSHLXXXXXXXXXX 1992
L+ ++G+++ + +DI+D + S L
Sbjct: 643 LLERKGVYFTLVTLQSQGNQALNE-EDIKDATEDDMLARTFSRGSYQDSLRASIRQRSKS 701
Query: 1993 XXXXXIHQLAEEVEECKA-----------------PPTSMFKIFKFNGDKVGWXXXXXXX 2121
+H+ V + K+ P + +I KF+ + +
Sbjct: 702 QLSYLVHEPPLAVVDHKSTYEEDRKDKDIPVQEEVEPAPVRRILKFSAPEWPYMLVGSVG 761
Query: 2122 XXXXXSVTPVFALVYAEIFNVYSLP-ADQMQANVYFWCGMFVLMGITFFVGFFTSANCLG 2298
+VTP++A ++++I +S+P ++ ++ + C +FV MG F
Sbjct: 762 AAVNGTVTPLYAFLFSQILGTFSIPDKEEQRSQINGVCLLFVAMGCVSLFTQFLQGYAFA 821
Query: 2299 RCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLA 2475
+ GE LT +LR F+ +L QDIA++DDLR+ G L TR ATDA V+ +++ +++
Sbjct: 822 KSGELLTKRLRKFGFRAMLGQDIAWFDDLRNSPGALTTRLATDASQVQGAAGSQIGMIVN 881
Query: 2476 SIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVAS 2655
S + A+ I F + W+ + G + +M G RD Q LE G++ +
Sbjct: 882 SFTNVTVAMIIAFSFSWKLSLVILCFFPFLALSGATQTRMLTGFASRDKQALEMVGQITN 941
Query: 2656 QAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFY 2835
+A+ +IRTV + ++ +F L +PF T ++ A+ YG FAF+Q ++F +A++
Sbjct: 942 EALSNIRTVAGIGKERRFIEALETELEKPFKTAIQKANIYGFCFAFAQCIMFIANSASYR 1001
Query: 2836 LGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPI 3015
G ++ + + V+RV A+ +G S+ P KA+++A+ F L++ PI
Sbjct: 1002 YGGYLISNEGLHFSYVFRVISAVVLSATALGRAFSYTPSYAKAKISAARFFQLLDRQPPI 1061
Query: 3016 DSLSDSGIV-KPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKST 3192
+ +G G I + F YP+R D++VL G ++ I G+T+A VG SGCGKST
Sbjct: 1062 SVYNTAGEKWDNFQGKIDFVDCKFTYPSRPDSQVLNGLSVSISPGQTLAFVGSSGCGKST 1121
Query: 3193 IMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTN-R 3369
+ LLERFY+ D+G +MIDG + + +N+ LR + IVSQEP LF C+I +NI YG N +
Sbjct: 1122 SIQLLERFYDPDQGKVMIDGHDSKKVNVQFLRSNIGIVSQEPVLFACSIMDNIKYGDNTK 1181
Query: 3370 NVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLL 3549
+ + ++ AAK A +H+F++ LP+ Y+T+VG +G+QLS G+KQRIAIARA+VR P +LL
Sbjct: 1182 EIPMERVIAAAKQAQLHDFVMSLPEKYETNVGSQGSQLSRGEKQRIAIARAIVRDPKILL 1241
Query: 3550 LDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHD 3729
LDEATSALDTESEK VQ ALD A++GRTC+VIAHRLSTIQN+D+IA++++G ++EKGTH+
Sbjct: 1242 LDEATSALDTESEKTVQVALDKAREGRTCIVIAHRLSTIQNADIIAVMAQGVVIEKGTHE 1301
Query: 3730 ELIRKSEIYQKFCET 3774
EL+ + Y K T
Sbjct: 1302 ELMAQKGAYYKLVTT 1316
>gi|17569143|ref|NP_509901.1| P-GlycoProtein related (pgp-3)
[Caenorhabditis elegans]
gi|29429184|sp|P34713|MDR3_CAEEL Multidrug resistance protein 3
(P-glycoprotein C)
gi|7511155|pir||T22094 hypothetical protein ZK455.7 - Caenorhabditis
elegans
gi|3877009|emb|CAA91467.1| Hypothetical protein ZK455.7
[Caenorhabditis elegans]
gi|3881645|emb|CAA91495.1| C. elegans PGP-3 protein (corresponding
sequence ZK455.7) [Caenorhabditis elegans]
Length = 1268
Score = 881 bits (2276), Expect = 0.0
Identities = 482/1250 (38%), Positives = 717/1250 (56%), Gaps = 26/1250 (2%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNP 285
+ +F D +L G + + ++GA P +++ G+ + + S + G
Sbjct: 32 FDVFRDADYKDYILFSGGLILSAVNGALVPFNSLIFEGIANALMEGE-SQYQNGT----- 85
Query: 286 EGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAIL 465
I++ F+SE+ +C+ Y LGV +F SY +C + ER +H +R+ YLK++L
Sbjct: 86 -----INMPWFSSEIKMFCLRYFYLGVALFLCSYFANSCLYTLCERRLHCIRKKYLKSVL 140
Query: 466 RQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTL 645
RQ +WFD+ G LT +++ +E++++G+GDK +LV A F++G +GF+ W +TL
Sbjct: 141 RQDAKWFDETTIGGLTQKMSSGIEKIKDGIGDKVGVLVGGVATFISGVSIGFYMCWQLTL 200
Query: 646 VMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDR 825
VMM PL + S +K + T+ E Y+ AG +A E + IRTV + N E++R
Sbjct: 201 VMMITVPLQLGSMYLSAKHLNRATKNEMSAYSNAGGMANEVIAGIRTVMAFNAQPFEINR 260
Query: 826 FYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVF 1005
+ + L R+ GI K + I F + M++ A+AFWYG+TL G +F VF
Sbjct: 261 YAHQLNEARRMGIRKAIILAICTAFPLMLMFTCMAVAFWYGATLAAAGAV-SSGAVFAVF 319
Query: 1006 FAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFK 1185
+AVL G+ LG A PHL + AR A + +VI+ P+I S EG + + ++G ++F
Sbjct: 320 WAVLIGTRRLGEAAPHLGAITGARLAIHDIFKVIDHEPEIKCTSSEGKIPEKIQGKLTFD 379
Query: 1186 DVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDG 1365
+ F YP+R ++ +LKG+S E+ G+ +ALVG SGCGKST + LL RFY+ G + +DG
Sbjct: 380 GIEFTYPTRPELKILKGVSFEVNPGETVALVGHSGCGKSTSIGLLMRFYNQCAGMIKLDG 439
Query: 1366 VDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKR 1545
+ ++E N+ LR IGIV QEP++F T+ ENI+MG+ T + EACKMANA++FI +
Sbjct: 440 IPIQEYNIRWLRSTIGIVQQEPIIFVATVAENIRMGDVLITDQDIEEACKMANAHEFICK 499
Query: 1546 LPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQ 1725
L D Y T +G VQLSGGQKQR+AIARA+V+ P+ILLLDEATSALDTE+ER VQ ALD+
Sbjct: 500 LSDRYDTVIGAGAVQLSGGQKQRVAIARAIVRKPQILLLDEATSALDTESERMVQTALDK 559
Query: 1726 AQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSK-QGIFYDMTXXXXXXXX 1902
A GRTT+ +AHRLSTIRN +I VF G I E G+H+EL+SK GI+ M
Sbjct: 560 ASEGRTTLCIAHRLSTIRNASKILVFDQGLIAERGTHDELISKDDGIYASMVKAQEIERA 619
Query: 1903 XXEAGKDIEDTISESAH------------------------SHLXXXXXXXXXXXXXXXI 2010
+ D E+ E H + L I
Sbjct: 620 KEDTTLDDEE--DEKTHRSFHRDSVTSDEERELQQSLARDSTRLRQSMISTTTQVPEWEI 677
Query: 2011 HQLAEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYS 2190
EE+ E A S+F IFK+ ++ P F++VY ++F + S
Sbjct: 678 ENAREEMIEEGAMEASLFDIFKYASPEMRNIIISLVFTLIRGFTWPAFSIVYGQLFKILS 737
Query: 2191 LPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIA 2370
D + F+L+ T + S + LG+ GE+++ +LR + F+N+++QD +
Sbjct: 738 AGGDDVSIKALLNSLWFILLAFTGGISTLISGSLLGKAGETMSGRLRMDVFRNIMQQDAS 797
Query: 2371 FYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXX 2547
++DD RH G L +R ATDAPNV+ + RL VL IV++ +G+ FYYGW
Sbjct: 798 YFDDSRHNVGSLTSRLATDAPNVQAAIDQRLAEVLTGIVSLFCGVGVAFYYGWNMAPIGL 857
Query: 2548 XXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCE 2727
+ Q + RD EA ++ ++++ + +TV +L +QE + +
Sbjct: 858 ATALLLVVVQSSVAQYLKFRGQRDMDSAIEASRLVTESISNWKTVQALTKQEYMYDAFTA 917
Query: 2728 YLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAIS 2907
+ P + FA + S + + +A A+ G ++ P V++V A++
Sbjct: 918 ASKSPHRRAIVRGLWQSLSFALAGSFVMWNFAIAYMFGLWLISNNWSTPYTVFQVIEALN 977
Query: 2908 FCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVFFN 3087
+ S+ P+ V+AR++A ++F +I + ID+ +G I GNI++R V+F
Sbjct: 978 MASMSVMLAASYFPEYVRARISAGIMFTMIRQKSVIDNRGLTGDTPTIKGNINMRGVYFA 1037
Query: 3088 YPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRN 3267
YP R+ VL GF + G+TVALVG SGCGKST + L+ER+Y+ G + ID +IR+
Sbjct: 1038 YPNRRRQLVLDGFNMSANFGQTVALVGPSGCGKSTTIQLIERYYDALCGSVKIDDSDIRD 1097
Query: 3268 LNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDG 3447
L++ LR+ + +V QEPTLF+ TI ENI YG N+T ++ +AA +ANIH F++GLPDG
Sbjct: 1098 LSVKHLRDNIALVGQEPTLFNLTIRENITYGL-ENITQDQVEKAATLANIHTFVMGLPDG 1156
Query: 3448 YDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQG 3627
YDT VG G +LSGGQKQR+AIARA+VR P +LLLDEATSALDTESEKIVQEALD A+ G
Sbjct: 1157 YDTSVGASGGRLSGGQKQRVAIARAIVRDPKILLLDEATSALDTESEKIVQEALDKARLG 1216
Query: 3628 RTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
RTC+VIAHRLSTIQN+D I + GK +E+GTH L+ + +Y + E Q
Sbjct: 1217 RTCVVIAHRLSTIQNADKIIVCRNGKAIEEGTHQTLLARRGLYYRLVEKQ 1266
>gi|11038656|ref|NP_066302.1| ATP-binding cassette, sub-family B,
member 11; bile salt export pump; sister of
P-glycoprotein [Mus musculus]
gi|12643304|sp|Q9QY30|AB11_MOUSE Bile salt export pump (ATP-binding
cassette, sub-family B, member 11) (Sister of
P-glycoprotein)
gi|6502606|gb|AAF14372.1| liver bile salt export pump;
sister-of-p-glycoprotein [Mus musculus domesticus]
Length = 1321
Score = 877 bits (2265), Expect = 0.0
Identities = 493/1275 (38%), Positives = 745/1275 (57%), Gaps = 52/1275 (4%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQ------------- 246
+ +F ++ D L+ G+V A++HG P + IV G +T +F+
Sbjct: 48 FELFRFSSSKDNWLMFMGSVCALLHGMAQPGMIIVFGILTDIFVEYDIERQELSIPGKVC 107
Query: 247 --------NSDFVVGVDNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIAC 402
NS F + N GLV I NSEV+K+ Y +GV + Y QI
Sbjct: 108 MNNTIVWINSSFNQNMTNGTSCGLVDI-----NSEVIKFSGIYAGVGVAVLILGYFQIRL 162
Query: 403 FESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQ 582
+ R + K+R+ Y + I+R +I WFD G L +R +DD+ ++ E + D+ AL +Q
Sbjct: 163 WVITGARQIRKMRKFYFRRIMRMEIGWFDCTSVGELNSRFSDDINKIDEAIADQMALFLQ 222
Query: 583 MFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAE 762
+ L+G +GF+ W +TLV++ +PLI + A + S+A T +E + YA AG+IA+
Sbjct: 223 RLSTALSGLLLGFYRGWKLTLVILAVSPLIGIGAAVIGLSVAKFTELELKAYAKAGSIAD 282
Query: 763 ETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFW 942
E SSIRTV + G +E++R+ L ++ GI K MG G+ ++ YALAFW
Sbjct: 283 EVLSSIRTVAAFGGENKEVERYEKNLMFAQRWGIWKGMVMGFFTGYMWCLIFFCYALAFW 342
Query: 943 YGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPK 1122
YGS L++++ + G + +F V+ + ++G A L F T AAS++ + I+ P
Sbjct: 343 YGSRLVLDEGEYTPGTLIQIFLCVIIAAMNIGNASSCLEIFSTGCSAASSIFQTIDRQPV 402
Query: 1123 IDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKS 1302
+D S +G +D +KG+I F +V F YPSR ++ +L +S+ +K G+ A VGSSG GKS
Sbjct: 403 MDCMSGDGYKLDRIKGEIEFHNVTFHYPSRPEVKILNNLSMVIKPGETTAFVGSSGAGKS 462
Query: 1303 TIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEH 1482
T + L+QRFYDP +G V +DG D+R +N+ LR+QIGIV QEPVLF TI ENI++G E
Sbjct: 463 TALQLIQRFYDPCEGMVTLDGHDIRSLNIRWLRDQIGIVEQEPVLFSTTIAENIRLGREE 522
Query: 1483 ATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLL 1662
AT + +V+A K ANA +FI LP + T VGE G Q+SGGQKQR+AIARAL++ PKILLL
Sbjct: 523 ATMEDIVQAAKDANAYNFIMALPQQFDTLVGEGGGQMSGGQKQRVAIARALIRKPKILLL 582
Query: 1663 DEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEE 1842
D ATSALD E+E +VQGAL++ Q G T I VAHRLST+R+ D I F+ G VE G+HEE
Sbjct: 583 DMATSALDNESEAKVQGALNKIQHGHTIISVAHRLSTVRSADVIIGFEHGTAVERGTHEE 642
Query: 1843 LMSKQGIFYDM-TXXXXXXXXXXEAGKDIEDTI-------------------------SE 1944
L+ ++G+++ + T E G +DT S+
Sbjct: 643 LLERKGVYFMLVTLQSQEDNTHKETGIKGKDTTEGDTPERTFSRGSYQDSLRASIRQRSK 702
Query: 1945 SAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXX 2124
S SHL + +V + P + +I K+N + +
Sbjct: 703 SQLSHLSHEPPLAIGDHKSSYEDRKDNDVLVEEVEPAPVRRILKYNISEWPYILVGALCA 762
Query: 2125 XXXXSVTPVFALVYAEIFNVYSL-PADQMQANVYFWCGMFVLMG-ITFFVGFFTSANCLG 2298
+VTP+++L++++I +SL +Q ++ +Y C FV++G ++ F F N
Sbjct: 763 AINGAVTPIYSLLFSQILKTFSLVDKEQQRSEIYSMCLFFVILGCVSLFTQFLQGYN-FA 821
Query: 2299 RCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLA 2475
+ GE LT +LR FK +LRQDI ++DDL++ G L TR ATDA V+ +++ +++
Sbjct: 822 KSGELLTKRLRKFGFKAMLRQDIGWFDDLKNNPGVLTTRLATDASQVQGATGSQVGMMVN 881
Query: 2476 SIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVAS 2655
S I A+ I F + W+ + G + +M G +D ++LE+AG++ +
Sbjct: 882 SFTNIFVAVLIAFLFNWKLSLVISVFFPFLALSGAVQTKMLTGFASQDKEILEKAGQITN 941
Query: 2656 QAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFY 2835
+A+ +IRTV + + +F + L + + T ++ A+ YG +AFSQ + F +AA+
Sbjct: 942 EALSNIRTVAGIGVEGRFIKAFEVELEKSYKTAIRKANVYGLCYAFSQGISFLANSAAYR 1001
Query: 2836 LGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPI 3015
G + + + V+RV +I+ +G T S+ P KA+++A+ F L++ PI
Sbjct: 1002 YGGYLIVYEDLNFSYVFRVVSSIAMSATAVGRTFSYTPSYAKAKISAARFFQLLDRKPPI 1061
Query: 3016 DSLSDSGIV-KPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKST 3192
D S +G G I + F YP+R D +VL G ++ + G+T+A VG SGCGKST
Sbjct: 1062 DVYSGAGEKWDNFQGKIDFIDCKFTYPSRPDIQVLNGLSVSVDPGQTLAFVGSSGCGKST 1121
Query: 3193 IMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTN-R 3369
+ LLERFY+ D+G +MIDG + + +N+ LR + IVSQEP LFDC+I +NI YG N +
Sbjct: 1122 SIQLLERFYDPDQGTVMIDGHDSKKVNVQFLRSNIGIVSQEPVLFDCSIMDNIKYGDNTK 1181
Query: 3370 NVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLL 3549
++ + + AAK A +H+F++ LP+ Y+T+VG +G+QLS G+KQRIAIARA+VR P +LL
Sbjct: 1182 EISVERAIAAAKQAQLHDFVMSLPEKYETNVGIQGSQLSRGEKQRIAIARAIVRDPKILL 1241
Query: 3550 LDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHD 3729
LDEATSALDTESEK VQ ALD A++GRTC+VIAHRLSTIQNSD+IA++S+G ++EKGTH
Sbjct: 1242 LDEATSALDTESEKTVQLALDKAREGRTCIVIAHRLSTIQNSDIIAVMSQGVVIEKGTHK 1301
Query: 3730 ELIRKSEIYQKFCET 3774
+L+ + Y K T
Sbjct: 1302 KLMDQKGAYYKLVIT 1316
>gi|13929072|ref|NP_113948.1| ATP-binding cassette, sub-family B
(MDR/TAP), member 11; sister of P-glycoprotein; bile salt
export pump [Rattus norvegicus]
gi|12585136|sp|O70127|AB11_RAT Bile salt export pump (ATP-binding
cassette, sub-family B, member 11) (Sister of
P-glycoprotein)
gi|11346285|pir||T42842 bile salt transport protein, ATP-dependent -
rat
gi|3075422|gb|AAC40084.1| bile salt export pump [Rattus norvegicus]
Length = 1321
Score = 876 bits (2264), Expect = 0.0
Identities = 492/1284 (38%), Positives = 743/1284 (57%), Gaps = 56/1284 (4%)
Frame = +1
Query: 91 VKLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQ-------- 246
+++ + +F ++ D+ L++ G V A++HG P + I+ G MT +F++
Sbjct: 43 IRVGFFELFRFSSSKDIWLMLMGGVCALLHGMAQPGILIIFGIMTDIFIKYDIERQELEI 102
Query: 247 -------------NSDFVVGVDNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSY 387
NS F + N GLV I SE++K+ Y +G+ + Y
Sbjct: 103 PGKACVNNTIVWINSSFHQNMTNGTVCGLVDIE-----SEMIKFSGIYAGVGMTVLILGY 157
Query: 388 VQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKF 567
QI + R + ++R+ Y + I+R +I WFD G L +R DD+E++ + + D+
Sbjct: 158 FQIRLWVITGARQIRRMRKIYFRRIMRMEIGWFDCTSVGELNSRFADDIEKINDAIADQL 217
Query: 568 ALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVA 747
A +Q + + G +GF+ W +TLV++ +PLI + A + S+A T +E + YA A
Sbjct: 218 AHFLQRMSTAMCGLLLGFYRGWKLTLVILAVSPLIGIGAAVIGLSIAKFTELELKAYAKA 277
Query: 748 GAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSY 927
G+IA+E SSIRTV + G +E++R+ L ++ GI K MG G+ ++ Y
Sbjct: 278 GSIADEVLSSIRTVAAFGGENKEVERYEKNLVFAQRWGIWKGMVMGFFTGYMWCLIFFCY 337
Query: 928 ALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVI 1107
ALAFWYGSTL++++ + G + +F V+ + ++G A L F T AA+ + + I
Sbjct: 338 ALAFWYGSTLVLDEEEYTPGTLVQIFLCVILAAMNIGHASSCLEIFSTGCSAATNIFQTI 397
Query: 1108 NSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSS 1287
+ P ID S +G +D +KG+I F +V F YPSR D+ +L +S+ +K G+ ALVGSS
Sbjct: 398 DRQPVIDCMSGDGYKLDRIKGEIEFHNVTFHYPSRPDVKILDNLSMVIKPGETTALVGSS 457
Query: 1288 GCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIK 1467
G GKST + L+QRFYDP +G V +DG D+R +N+ LR+QIGIV QEPVLF TI ENI+
Sbjct: 458 GAGKSTALQLIQRFYDPCEGMVTLDGHDIRSLNIRWLRDQIGIVEQEPVLFSTTIAENIR 517
Query: 1468 MGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNP 1647
G E AT + +V+A K ANA +FI LP + T VGE G Q+SGGQKQR+AIARAL++NP
Sbjct: 518 FGREDATMEDIVQAAKDANAYNFIMALPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNP 577
Query: 1648 KILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVES 1827
KILLLD ATSALD E+E VQ AL++ Q G T I VAHRLST+R D I F+ G VE
Sbjct: 578 KILLLDMATSALDNESEARVQEALNKIQHGHTIISVAHRLSTVRAADVIIGFEHGVAVER 637
Query: 1828 GSHEELMSKQGIFYDMTXXXXXXXXXXE----AGKD------IEDTISESAH-SHLXXXX 1974
G+HEEL+ ++G+++ + + GKD +E T S ++ L
Sbjct: 638 GTHEELLERKGVYFMLVTLQSQGDNAHKETSIMGKDATEGGTLERTFSRGSYRDSLRASI 697
Query: 1975 XXXXXXXXXXXIHQ--------------------LAEEVEECKAPPTSMFKIFKFNGDKV 2094
H L EEVE P + +I K+N +
Sbjct: 698 RQRSKSQLSLLTHDPPLAVADHKSSYKDSKDNDVLVEEVE-----PAPVRRILKYNIPEW 752
Query: 2095 GWXXXXXXXXXXXXSVTPVFALVYAEIFNVYS-LPADQMQANVYFWCGMFVLMGITFFVG 2271
+ +VTP+++L+++++ +S L +Q ++ ++ C FV++G
Sbjct: 753 HYILVGSLSAAINGAVTPIYSLLFSQLLGTFSLLDKEQQRSEIHSMCLFFVILGCVSIFT 812
Query: 2272 FFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVR-YV 2448
F + GE LT +LR FK +L QDI ++DDLR+ G L TR ATDA V+
Sbjct: 813 QFLQGYTFAKSGELLTKRLRKFGFKAMLGQDIGWFDDLRNNPGVLTTRLATDASQVQGAT 872
Query: 2449 FTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQL 2628
+++ +++ S I AL I F++ W+ + G + +M G +D Q
Sbjct: 873 GSQVGMMVNSFTNIIAALLIAFFFSWKLSLIITIFFPFLALSGAVQTKMLTGFASQDKQA 932
Query: 2629 LEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLI 2808
LE+AG++ S+A+ +IRTV + + +F + L+ + T ++ A+ YG FAFSQ +
Sbjct: 933 LEKAGQITSEALSNIRTVAGIGVEGRFIKAFEVELQTSYKTAVRKANIYGLCFAFSQGIA 992
Query: 2809 FFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLF 2988
F +AA+ G + + + V+RV +++ +G T S+ P KA+++A+ F
Sbjct: 993 FLANSAAYRYGGYLIAYEGLGFSHVFRVVSSVALSATAVGRTFSYTPSYAKAKISAARFF 1052
Query: 2989 YLIEHPTPIDSLSDSGIV-KPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALV 3165
L++ PI+ S++G G I + F YP+R D +VL G ++ + G+T+A V
Sbjct: 1053 QLLDRKPPINVYSEAGEKWDNFQGKIDFIDCKFTYPSRPDIQVLNGLSVSVNPGQTLAFV 1112
Query: 3166 GHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGE 3345
G SGCGKST + LLERFY+ D+G +MIDG + + +NI LR + IVSQEP LFDC+I +
Sbjct: 1113 GSSGCGKSTSIQLLERFYDPDQGTVMIDGHDSKKVNIQFLRSNIGIVSQEPVLFDCSIMD 1172
Query: 3346 NICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARA 3522
NI YG N + ++ + + AAK A +H+F++ LP+ Y+T+VG +G+QLS G+KQRIAIARA
Sbjct: 1173 NIKYGDNTKEISVERAIAAAKQAQLHDFVMSLPEKYETNVGIQGSQLSRGEKQRIAIARA 1232
Query: 3523 LVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEG 3702
+VR P +LLLDEATSALDTESEK VQ ALD A++GRTC+VIAHRLSTIQNSD+IA+VS+G
Sbjct: 1233 IVRDPKILLLDEATSALDTESEKTVQTALDKAREGRTCIVIAHRLSTIQNSDIIAVVSQG 1292
Query: 3703 KIVEKGTHDELIRKSEIYQKFCET 3774
++EKGTH++L+ + Y K T
Sbjct: 1293 VVIEKGTHEKLMAQKGAYYKLVIT 1316
>gi|39594784|emb|CAE70652.1| Hypothetical protein CBG17357
[Caenorhabditis briggsae]
Length = 1268
Score = 875 bits (2262), Expect = 0.0
Identities = 474/1248 (37%), Positives = 719/1248 (56%), Gaps = 24/1248 (1%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNP 285
+ +F + D L+ G + + ++GA P +++ G+ + + + + G
Sbjct: 32 FDVFRDSDWRDYALVAGGIILSAVNGALVPFNSLIFEGIANALMEGE-AQYQNGT----- 85
Query: 286 EGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAIL 465
+++ F+SE+ +C+ Y LG+ +F SY AC + ER +H +R++YLK++L
Sbjct: 86 -----LNMPWFSSEIKFFCLRYFYLGLALFLCSYCANACLYTLCERRLHCIRKHYLKSVL 140
Query: 466 RQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTL 645
RQ +WFD+ G LT +++ +E++++G+GDK ++V A F++G +GF+ W +TL
Sbjct: 141 RQDAKWFDQHTIGGLTQKMSSGIEKIKDGIGDKIGVIVGGVATFISGVSLGFYMCWQLTL 200
Query: 646 VMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDR 825
VM+ PL + S +K + T+ E Y+ AG +A E + IRTV + N E++R
Sbjct: 201 VMLITVPLQLGSMYLSAKHLNRATKNEMSAYSNAGGMANEVIAGIRTVMAFNAQPFEINR 260
Query: 826 FYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVF 1005
+ LE R+ G+ K + I F + M++ A+AFWYG+TL G +F VF
Sbjct: 261 YSQQLEEARKMGVRKAMILAICTSFPLMLMFTCMAVAFWYGATLAAAGAV-SSGAVFAVF 319
Query: 1006 FAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFK 1185
+AVL G+ +G A PHL + AR A + +VI+ P+I S +G + D ++G +SF
Sbjct: 320 WAVLIGTRRIGEAAPHLGAITGARLAIHDIFKVIDHEPEIKCTSSDGKIPDKIQGKLSFD 379
Query: 1186 DVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDG 1365
+ F YP+R D+ +LKG+S E+ G+ +ALVG SGCGKST + LL RFY+ G + +DG
Sbjct: 380 GIEFTYPTRPDLKILKGVSFEVNPGETVALVGHSGCGKSTSIGLLMRFYNQGAGMIKLDG 439
Query: 1366 VDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKR 1545
V + E N+ LR IGIV QEP++F T+ ENI+MG++ T D + EAC+MANA++FI +
Sbjct: 440 VPIHEYNIRWLRSTIGIVQQEPIIFVATVAENIRMGDDLITDDDIEEACRMANAHEFICK 499
Query: 1546 LPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQ 1725
L D Y T +G VQLSGGQKQR+AIARA+V+ P+ILLLDEATSALDTE+ER VQ ALD+
Sbjct: 500 LSDKYNTVIGAGAVQLSGGQKQRVAIARAIVRRPQILLLDEATSALDTESERMVQAALDK 559
Query: 1726 AQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQ-GIFYDMTXXXXXXXX 1902
A GRTT+ +AHRLSTI+N +I VF G I E G+H+EL+SK+ GI+ M
Sbjct: 560 ASKGRTTLCIAHRLSTIKNASKILVFDQGLIAERGTHDELISKEDGIYASMVAAQEIERA 619
Query: 1903 XXEAGKDIEDTISESAHSH----------------------LXXXXXXXXXXXXXXXIHQ 2016
+ D E+ + H L I
Sbjct: 620 KEDTTLDDEEDEKDHRMFHRDSVTSDEERELQQSLARDSTRLRQSMISTTTQVPEWEIES 679
Query: 2017 LAEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLP 2196
EE+ E A S+ IFKF + P F++VY ++F + S
Sbjct: 680 AREEMIEEGAMEASLVDIFKFASPEGRNIIIALVFTLIRGLTWPAFSIVYGQLFRILSAG 739
Query: 2197 ADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFY 2376
D + F+L+ T + S LG+ GE+++ +LR + F+N+++QD +++
Sbjct: 740 GDDVSIKALLNSLWFLLLAFTSGISTLVSGGLLGKAGETMSGRLRMDVFRNIMQQDASYF 799
Query: 2377 DDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXX 2553
DD +H G L +R ATDAPNV+ + RL VL +V++ + + F+YGW
Sbjct: 800 DDPKHNVGALTSRLATDAPNVQAAIDQRLAEVLTGVVSLFCGVSVAFFYGWNMAPIGLAT 859
Query: 2554 XXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYL 2733
+ Q + RD EA ++ ++++ + +TV SL +QE + ++
Sbjct: 860 ALLLVVVQSAVAQYLKFRGQRDMDSAIEASRLVTESISNWKTVQSLTKQEYMYDSFVAAS 919
Query: 2734 REPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFC 2913
+ P + FA + S + + +A A+ G ++ P V++V A++
Sbjct: 920 KSPHRRAIVRGLWQSLSFALAGSFVMWNFAIAYMFGLWLISNGWSTPYTVFQVIEALNMA 979
Query: 2914 GQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYP 3093
+ S+ P+ V+AR++A ++F +I + ID+ +G PI G+IS+R V+F YP
Sbjct: 980 SMSVMLAASYFPEYVRARISAGIMFTMIRQRSVIDNRGLTGDTPPIKGDISMREVYFAYP 1039
Query: 3094 TRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLN 3273
R+ VL F + K G+TVALVG SGCGKST + L+ER+Y+ G I +DG +IR ++
Sbjct: 1040 NRRRQLVLDSFNMTAKFGQTVALVGPSGCGKSTTIQLIERYYDALSGKIKVDGCDIREIS 1099
Query: 3274 ISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYD 3453
+ LR+ + +V QEPTLF+ TI ENI YG + ++ +E+ +AA +ANIH F++GLP+GYD
Sbjct: 1100 VKHLRDNIALVGQEPTLFNLTIRENITYGLEK-ISQEEVEKAATLANIHTFVMGLPEGYD 1158
Query: 3454 THVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRT 3633
T VG G +LSGGQKQR+AIARA+VR P +LLLDEATSALDTESEKIVQEALD A+ GRT
Sbjct: 1159 TSVGASGGRLSGGQKQRVAIARAIVRDPKILLLDEATSALDTESEKIVQEALDKARLGRT 1218
Query: 3634 CLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
C+VIAHRLSTIQN+D I + GK +E+GTH L+ + +Y + E Q
Sbjct: 1219 CIVIAHRLSTIQNADKIIVCRNGKAIEEGTHQTLLARRGLYYRLVEKQ 1266
>gi|7514034|pir||T42228 P-glycoprotein sister - rat
gi|3273484|gb|AAC24753.1| P-glycoprotein sister [Rattus norvegicus]
Length = 1321
Score = 875 bits (2261), Expect = 0.0
Identities = 492/1284 (38%), Positives = 742/1284 (57%), Gaps = 56/1284 (4%)
Frame = +1
Query: 91 VKLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQ-------- 246
+++ + +F ++ D+ L++ G V A++HG P + I+ G MT +F++
Sbjct: 43 IRVGFFELFRFSSSKDIWLMLMGGVCALLHGMAQPGILIIFGIMTDIFIKYDIERQELEI 102
Query: 247 -------------NSDFVVGVDNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSY 387
NS F + N GLV I SE++K+ Y +G+ + Y
Sbjct: 103 PGKACVNNTIVWINSSFHQNMTNGTVCGLVDIE-----SEMIKFSGIYAGVGMTVLILGY 157
Query: 388 VQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKF 567
QI + R + ++R+ Y + I+R +I WFD G L +R DD+E++ + + D+
Sbjct: 158 FQIRLWVITGARQIRRMRKIYFRRIMRMEIGWFDCTSVGELNSRFADDIEKINDAIADQL 217
Query: 568 ALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVA 747
A +Q + + G +GF+ W +TLV++ +PLI + A + S+A T +E + YA A
Sbjct: 218 AHFLQRMSTAMCGLLLGFYRGWKLTLVILAVSPLIGIGAAVIGLSIAKFTELELKAYAKA 277
Query: 748 GAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSY 927
G+IA+E SSIRTV + G +E++R+ L ++ GI K MG G+ ++ Y
Sbjct: 278 GSIADEVLSSIRTVAAFGGENKEVERYEKNLVFAQRWGIWKGMVMGFFTGYMWCLIFFCY 337
Query: 928 ALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVI 1107
ALAFWYGSTL++++ + G + +F V+ + ++G A L F T AA+ + + I
Sbjct: 338 ALAFWYGSTLVLDEEEYTPGTLVQIFLCVILAAMNIGHASSCLEIFSTGCSAATNIFQTI 397
Query: 1108 NSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSS 1287
+ P ID S +G +D +KG+I F +V F YPSR D+ +L +S+ +K G+ ALVGSS
Sbjct: 398 DRQPVIDCMSGDGYKLDRIKGEIEFHNVTFHYPSRPDVKILDNLSMVIKPGETTALVGSS 457
Query: 1288 GCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIK 1467
G GKST + L+QRFYDP +G V +DG D+R +N+ LR+QIGIV QEPVLF TI ENI+
Sbjct: 458 GAGKSTALQLIQRFYDPCEGMVTLDGHDIRSLNIRWLRDQIGIVEQEPVLFSTTIAENIR 517
Query: 1468 MGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNP 1647
G E AT + +V+A K ANA +FI LP + T VGE G Q+SGGQKQR+AIARAL++NP
Sbjct: 518 FGREDATMEDIVQAAKDANAYNFIMALPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNP 577
Query: 1648 KILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVES 1827
KILLLD ATSALD E+E VQ AL++ Q G T I VAHRLST+R D I F+ G VE
Sbjct: 578 KILLLDMATSALDNESEARVQEALNKIQHGHTIISVAHRLSTVRAADVIIGFEHGVAVER 637
Query: 1828 GSHEELMSKQGIFYDMTXXXXXXXXXXE----AGKD------IEDTISESAH-SHLXXXX 1974
G+HEEL+ ++G+++ + + GKD +E T S ++ L
Sbjct: 638 GTHEELLERKGVYFMLVTLQSQGDNAHKETSIMGKDATEGGTLERTFSRGSYRDSLRASI 697
Query: 1975 XXXXXXXXXXXIHQ--------------------LAEEVEECKAPPTSMFKIFKFNGDKV 2094
H L EEVE P + +I K+N +
Sbjct: 698 RQRSKSQLSLLTHDPPLAVADHKSSYKDSKDNDVLVEEVE-----PAPVRRILKYNIPEW 752
Query: 2095 GWXXXXXXXXXXXXSVTPVFALVYAEIFNVYS-LPADQMQANVYFWCGMFVLMGITFFVG 2271
+ +VTP+++L+++++ +S L +Q ++ ++ C FV++G
Sbjct: 753 HYILVGSLSAAINGAVTPIYSLLFSQLLGTFSLLDKEQQRSEIHSMCLFFVILGCVSIFT 812
Query: 2272 FFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVR-YV 2448
F + GE LT +LR FK +L QDI ++DDLR+ G L TR ATDA V+
Sbjct: 813 QFLQGYTFAKSGELLTKRLRKFGFKAMLGQDIGWFDDLRNNPGVLTTRLATDASQVQGAT 872
Query: 2449 FTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQL 2628
+++ +++ S I AL I F++ W+ + G + +M G +D Q
Sbjct: 873 GSQVGMMVNSFTNIIAALLIAFFFSWKLSLIITIFFPFLALSGAVQTKMLTGFASQDKQA 932
Query: 2629 LEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLI 2808
LE+AG++ S+A+ +IRTV + + +F + L+ + T ++ A+ YG FAFSQ +
Sbjct: 933 LEKAGQITSEALSNIRTVAGIGVEGRFIKAFEVELQTSYKTAVRKANIYGLCFAFSQGIA 992
Query: 2809 FFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLF 2988
F +AA+ G + + + V+RV ++ +G T S+ P KA+++A+ F
Sbjct: 993 FLANSAAYRYGGYLIAYEGLGFSHVFRVVSSVVLSATAVGRTFSYTPSYAKAKISAARFF 1052
Query: 2989 YLIEHPTPIDSLSDSGIV-KPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALV 3165
L++ PI+ S++G G I + F YP+R D +VL G ++ + G+T+A V
Sbjct: 1053 QLLDRKPPINVYSEAGEKWDNFQGKIDFIDCKFTYPSRPDIQVLNGLSVSVNPGQTLAFV 1112
Query: 3166 GHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGE 3345
G SGCGKST + LLERFY+ D+G +MIDG + + +NI LR + IVSQEP LFDC+I +
Sbjct: 1113 GSSGCGKSTSIQLLERFYDPDQGTVMIDGHDSKKVNIQFLRSNIGIVSQEPVLFDCSIMD 1172
Query: 3346 NICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARA 3522
NI YG N + ++ + + AAK A +H+F++ LP+ Y+T+VG +G+QLS G+KQRIAIARA
Sbjct: 1173 NIKYGDNTKEISVERAIAAAKQAQLHDFVMSLPEKYETNVGIQGSQLSRGEKQRIAIARA 1232
Query: 3523 LVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEG 3702
+VR P +LLLDEATSALDTESEK VQ ALD A++GRTC+VIAHRLSTIQNSD+IA+VS+G
Sbjct: 1233 IVRDPKILLLDEATSALDTESEKTVQTALDKAREGRTCIVIAHRLSTIQNSDIIAVVSQG 1292
Query: 3703 KIVEKGTHDELIRKSEIYQKFCET 3774
++EKGTH++L+ + Y K T
Sbjct: 1293 VVIEKGTHEKLMAQKGAYYKLVIT 1316
>gi|40644167|emb|CAC86593.1| sister of P-glycoprotein [Platichthys
flesus]
gi|40644169|emb|CAC86594.1| sister of P-glycoprotein [Platichthys
flesus]
Length = 1356
Score = 872 bits (2253), Expect = 0.0
Identities = 492/1300 (37%), Positives = 735/1300 (55%), Gaps = 72/1300 (5%)
Frame = +1
Query: 91 VKLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQ-------- 246
+++ + +F ++ ++++++ G+V AV+HG+ PL+ +V G +T F+
Sbjct: 53 IRVGFFQLFRFSTCREVVMMVIGSVCAVLHGSAQPLMLLVFGLLTDTFIEYDIELNELRD 112
Query: 247 ------------NSDFVVGVD------NVNPEGLVPIS-----LDEFNSEVVKYCIYYLV 357
SD+ ++ N E LVP+ + + E+ K+ +YY+
Sbjct: 113 VRKECVNNTIQWKSDYTAALNQSDWSLNSTWEVLVPLKNLTCGVLDIEYEMTKFALYYVG 172
Query: 358 LGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTARLTDDLE 537
+ +F Y+QI+ + A R V +R+ Y ++R +I WFD G L R++DD+
Sbjct: 173 IAFAVFLLGYLQISLWVQAAARQVQIVRKMYFSKVMRMEIGWFDCTSVGELNTRMSDDIN 232
Query: 538 RVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRT 717
++ + + D+ A+ +Q F F+ G+ +GF W +TLV++ +PLI + M+ +A T
Sbjct: 233 KINDAIADQVAIFLQRFTTFVCGFCIGFVKGWKLTLVIVAASPLIGIGAGFMALFVAKLT 292
Query: 718 RVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVG 897
E + YA AGA+A+E SSIRTV + G +E+ R+ L ++ GI K MG G
Sbjct: 293 GRELQAYAKAGAVADEVLSSIRTVSAFGGELKEVQRYDRNLISAQRWGIRKGMIMGFFTG 352
Query: 898 FSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTAR 1077
+ L ++ YALAFWYGS L+++ + G + VFF VL + +LG A P L +F R
Sbjct: 353 YMWLIIFLCYALAFWYGSGLVLDTAEYTPGTLLQVFFGVLIAAMNLGQASPCLEAFAAGR 412
Query: 1078 GAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKA 1257
GAA+ + I+ P+ID S G +D +KGDI F +V F YPSR ++ L +S+ +K+
Sbjct: 413 GAATIIFETIDREPEIDCLSEAGYKLDRVKGDIEFHNVTFHYPSRPEVKTLDQLSVAVKS 472
Query: 1258 GDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVL 1437
G+ A VG SG GKST + L QRFYDP +G V +DG D+R +N+ LR IGIV QEPVL
Sbjct: 473 GETTAFVGPSGAGKSTAIQLFQRFYDPKEGMVTLDGHDIRGLNIQWLRSLIGIVEQEPVL 532
Query: 1438 FDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRI 1617
F TI ENI G + + +V A K ANA FI+ LP + T VGE G Q+SGGQKQRI
Sbjct: 533 FATTIAENICYGRPGVSMEDIVAAAKEANAYHFIQDLPQKFNTMVGEGGGQMSGGQKQRI 592
Query: 1618 AIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIF 1797
AIARALV+NP+ILLLD ATSALD E+E VQ ALD+ + GRTTI +AHRLSTI+N D I
Sbjct: 593 AIARALVRNPRILLLDMATSALDNESEAIVQEALDKVRLGRTTISIAHRLSTIKNADVIV 652
Query: 1798 VFKAGNIVESGSHEELMSKQGIFYDM-TXXXXXXXXXXEAGKDIEDTISESAHSHLXXXX 1974
F+ G VE G H EL+ ++G+++ + T E + + + E +L
Sbjct: 653 GFEHGRAVEKGKHGELLERKGVYFMLVTLQSQGDKALNEKARQLAEKEEEPVKQNLSRAG 712
Query: 1975 XXXXXXXXX-----------------------------------XXIHQLAEEVEECKAP 2049
+ EE EE
Sbjct: 713 SYRASLRSSIRQRSRSQLSNLIPDSSASMVGELGPRTYTFSQPDTSKADIPEEEEEEVVE 772
Query: 2050 PTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSL--PADQMQANVY 2223
P + +I K+N + + V PV++L++++I +S+ P Q + +
Sbjct: 773 PAPVARILKYNIPEWPYMLFGSIGAAINGGVNPVYSLLFSQILATFSVTDPVAQ-RKEID 831
Query: 2224 FWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGK 2403
C FV++G+ + GE LT +LR F +L Q+I ++DD R+ G
Sbjct: 832 SICMFFVMVGVVSSFTQMLQGYAFSKSGELLTRRLRRLGFHAMLGQEIGWFDDHRNSPGA 891
Query: 2404 LCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGY 2580
L TR ATDA V+ +++ +++ S+ I A+ + FY+ W+ + G
Sbjct: 892 LTTRLATDASQVQGATGSQIGMIVNSLTNIGVAVLMSFYFSWKLTMLILCFLPFIALSGG 951
Query: 2581 FEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLK 2760
F+ +M G +D + +E AG+++ +A+ +IRT+ L +++ F Y L PF LK
Sbjct: 952 FQAKMLTGFAKQDKEAMEAAGRISGEALNNIRTIAGLGKEQSFVDMYEAQLDGPFQAALK 1011
Query: 2761 HAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTS 2940
AH YGA + F+Q ++F +A++ G V Q+ + V+RV AI G +G +S
Sbjct: 1012 KAHVYGACYGFAQCVVFLTNSASYRFGGYLVRQEGLHFSLVFRVISAIVTSGTALGKASS 1071
Query: 2941 FIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIV-KPITGNISIRNVFFNYPTRKDTKVL 3117
+ PD KA+++A+ F L++ I SD G GN+ + F YPTR D +VL
Sbjct: 1072 YTPDYAKAKISAARFFKLLDRVPQISVYSDKGDKWDNFQGNLEFIDCKFTYPTRPDIQVL 1131
Query: 3118 QGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQV 3297
G + ++ G+T+A VG SGCGKST + LLERFY+ D G ++IDG + +N+ LR ++
Sbjct: 1132 NGLNVSVRPGQTLAFVGSSGCGKSTSVQLLERFYDPDHGRVLIDGHDSTGVNVPFLRSKI 1191
Query: 3298 CIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKG 3474
IVSQEP LFDC+I +NI YG N R ++ +++ AAK A +HNF++ LP+ YDT+VG +G
Sbjct: 1192 GIVSQEPILFDCSIADNIKYGDNSREISLNDVMSAAKKAQLHNFVMALPEKYDTNVGAQG 1251
Query: 3475 TQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHR 3654
+QLS GQKQRIAIARA++R P +LLLDEATSALDTESEKIVQEALD A++GRTC+VIAHR
Sbjct: 1252 SQLSRGQKQRIAIARAIIRDPKILLLDEATSALDTESEKIVQEALDKAREGRTCIVIAHR 1311
Query: 3655 LSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCET 3774
LSTIQNSD+IA++S G ++EKGTH++L+ Y K T
Sbjct: 1312 LSTIQNSDIIAVMSRGYVIEKGTHNQLMLLKGAYYKLVTT 1351
>gi|31213429|ref|XP_315658.1| ENSANGP00000021663 [Anopheles gambiae]
gi|21299609|gb|EAA11754.1| ENSANGP00000021663 [Anopheles gambiae str.
PEST]
Length = 1243
Score = 865 bits (2234), Expect = 0.0
Identities = 488/1247 (39%), Positives = 719/1247 (57%), Gaps = 24/1247 (1%)
Frame = +1
Query: 115 FYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGL 294
F + ++ + G + A + G P I+ G TT+ + D +G+ +
Sbjct: 1 FRFATWGEVCATLMGVLLASMASLGLPYGVILYGEFTTLLV-----DRTIGIGKSTDTAI 55
Query: 295 VPI---------SLDEFNSEVVKYCIYYLVLGV-----LMFFTSYVQIACFESYAERLVH 432
+ I + ++ N+ + LGV L F + + + A++ +
Sbjct: 56 LSIFGGGRVLVNATEQENAAAIMEDAKAFGLGVVAVTILQFIFATLSVDVINRSAQKQIS 115
Query: 433 KLRQNYLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYG 612
++RQ +LKA+LRQ + W+D + R+TDDL++++EG+G+K ++ + +F+
Sbjct: 116 RIRQLFLKAVLRQDMTWYDLNSDDSFAVRITDDLDKLKEGIGEKLSIFTYLVMSFVISVI 175
Query: 613 VGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVH 792
FFY W +TLV++ AP+I+L+ A ++K +T T E ++Y+ AGA+AEE SIRTV
Sbjct: 176 FSFFYGWKLTLVILSCAPIIILATAFVAKMQSTLTEKELKSYSSAGAVAEEVLGSIRTVV 235
Query: 793 SLNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDP 972
+ G K+E DR+ L G K + GIG G +Y YALAFWYG +LI+ D
Sbjct: 236 AFGGEKKEADRYRERLAGAELNGRRKGLFSGIGGGIMWFIIYCCYALAFWYGISLILEDR 295
Query: 973 TFDR-----GLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYS 1137
D ++ V F VL+G+ +LG + PHL +F TA+G+A+T+ VI+ P ID
Sbjct: 296 DKDLKDYTPAVLIIVLFGVLAGAQNLGLSSPHLEAFSTAKGSAATIFSVIDRIPVIDSLG 355
Query: 1138 LEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNL 1317
G+ +M+G+I F +V FRYP+R D+ VL+G++LE+K G +ALVG SGCGKST + L
Sbjct: 356 DAGLRPGSMQGNIKFSNVFFRYPARNDVQVLQGLNLEIKTGQTVALVGPSGCGKSTCLQL 415
Query: 1318 LQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQ 1497
+QR YDP G V IDG + E+N+ LR IG+V QEPVLF TI ENI+ GN A+ +
Sbjct: 416 IQRLYDPLSGSVTIDGTKVSELNIGWLRSFIGLVGQEPVLFATTIAENIRYGNPDASQSE 475
Query: 1498 VVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATS 1677
+ A K+AN + FI +LP+GY T +GE+G QLSGGQKQRIAIARALV+NPKILLLDEATS
Sbjct: 476 IERAAKIANCHSFITKLPNGYATMIGERGAQLSGGQKQRIAIARALVRNPKILLLDEATS 535
Query: 1678 ALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQ 1857
ALD +E+ VQ AL++A GRTT++V+HRLSTI N D+I G ++E G+HEELM+ +
Sbjct: 536 ALDPNSEKRVQDALERASKGRTTLVVSHRLSTITNADKIVYIDKGLVMEQGTHEELMAAR 595
Query: 1858 GIFYDMTXXXXXXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEE 2037
G++YD+ + + S E E+
Sbjct: 596 GLYYDLVVASGSQKTVDDDESVPMAPSALSMRQESVDDGAEASDDESDSGKSDEKNEEEQ 655
Query: 2038 CKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSL-PADQMQA 2214
+ S+ ++ K N + + + P FA+++ E++ + S+ + ++
Sbjct: 656 EEVYHVSLMRLLKLNAPEWHYILFGCAAAIVVGASFPAFAVLFGEMYGILSVADPEYVKE 715
Query: 2215 NVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHG 2394
F+ +F+++G+ VG F G LT +LR ++FK ++ QD+A++D+ R+
Sbjct: 716 ESNFYSFLFLVLGLITGVGTFFQTYLFNIAGVRLTSRLRQKSFKAIVSQDMAWFDESRNA 775
Query: 2395 TGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXM 2571
G LC R + D +V+ TR+ +L + TIC +GI F+Y W
Sbjct: 776 VGALCARLSGDCASVQGATGTRIGSLLQAASTICIGVGISFFYSWNLTLVSIIAIPVTLA 835
Query: 2572 GGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNT 2751
E + +++ Q E A K+A +A+ +IRTV SL +++ Y E + +
Sbjct: 836 SITLESRYSQTSSLKEKQSQEGATKLAVEAISNIRTVASLGQEKHVLQRYGEETVKIDDA 895
Query: 2752 NLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGN 2931
+ G VFA Q + F Y A + G V+++ ++ DV +V A+ F M+G
Sbjct: 896 CRRKTRLRGTVFALGQVMPFAGYGLALFYGGKLVSEKELEYKDVIKVSEALIFGAWMLGQ 955
Query: 2932 TTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDS--GIVKPITGNISIRNVFFNYPTRKD 3105
++ P+V A L+A L L++ + + S S + + G+I +V F YPTR
Sbjct: 956 ALAYAPNVNSAILSAGRLMKLLDRTPRMHNPSTSYHSLSQRTEGDIKFTDVEFRYPTRPT 1015
Query: 3106 TKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSL 3285
VLQG LDI G+TVALVG SGCGKST + LL R+Y+ D G + IDG +++ +
Sbjct: 1016 VPVLQGLNLDIGKGQTVALVGPSGCGKSTCIQLLLRYYDPDSGKVDIDGTTTTEFSLNRI 1075
Query: 3286 REQVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHV 3462
R Q+ +VSQEP LFD TI ENI YG N R + EI+EAAKMANIH FI+ LP GYDT +
Sbjct: 1076 RAQMGLVSQEPILFDRTIAENIAYGDNTREIAMPEIMEAAKMANIHEFIVNLPKGYDTSL 1135
Query: 3463 GEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLV 3642
G KG QLSGGQKQRIAIARALVR+P VLLLDEATSALD +SEKIVQ ALD A+ GRTC++
Sbjct: 1136 GSKGAQLSGGQKQRIAIARALVRNPRVLLLDEATSALDNQSEKIVQNALDHARTGRTCII 1195
Query: 3643 IAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRI 3783
IAHRL+TIQN+++I ++ G +VE GTHDEL+ KS IY K + Q++
Sbjct: 1196 IAHRLTTIQNANLICVIQNGVVVEAGTHDELMAKSRIYAKLYQMQQV 1242
>gi|18496816|gb|AAL74249.1| ABC transporter AbcB2 [Dictyostelium
discoideum]
Length = 1407
Score = 864 bits (2232), Expect = 0.0
Identities = 504/1308 (38%), Positives = 750/1308 (56%), Gaps = 84/1308 (6%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNP 285
+ +F + + D+LL+I GT+ A+ +G P ++IV G + F +P
Sbjct: 126 FSLFRFAKPFDILLMIIGTIGALANGVSMPAISIVFGRLMNSF---------------SP 170
Query: 286 EGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAIL 465
E L + D + V +Y++ +G +F SYV++A + ER + R+ YLKAIL
Sbjct: 171 ENLADPNFDLVET-VTSNAMYFIYIGCGVFVCSYVEVAFWMLAGERQAVRCRKAYLKAIL 229
Query: 466 RQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGF-------- 621
+Q+I W+D ++ L+ R++ D +E +G+K + + F+ G+ VGF
Sbjct: 230 KQEIGWYDVTKSSELSTRISSDTLLFQEAIGEKIGNFLHHTSTFICGFIVGFVNGKNYNY 289
Query: 622 --FYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHS 795
F+ W +TLV+ PLI +GA M+K MA T+ Q+ YA AG +AEE SIRTV +
Sbjct: 290 YLFFCWQLTLVIFALTPLIAAAGAFMTKMMADLTKKGQDAYAKAGGVAEEKIGSIRTVST 349
Query: 796 LNGH----KRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLII 963
+G KR +R AL++G + GI+ GIG+G L ++ +Y+L+FWYG LI+
Sbjct: 350 FSGEPFEVKRYTERLKEALDIGTKKGIMN----GIGIGLVFLVLFGTYSLSFWYGGKLIV 405
Query: 964 N---DPTFDR----GLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPK 1122
+ +P DR G + TVFF+V+ G+ +LG A P++ASF RGAA + V++ + K
Sbjct: 406 DRKWNPVPDRPWQGGDVLTVFFSVIMGAMALGQASPNVASFANGRGAAFKIYEVVDRNSK 465
Query: 1123 IDPYSLEGILVDN-MKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGK 1299
IDP+S EG ++ ++G+I ++++ F YPSR D+ + +L +K G +ALVG SG GK
Sbjct: 466 IDPFSTEGRSIEETVQGNIEYRNIGFSYPSRPDVKIFNNFNLTIKKGTTVALVGDSGGGK 525
Query: 1300 STIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNE 1479
S+++ LL+RFYDP +G V +DG +++E+N+HSLR IG+VSQEPVLF +I ENI+ GNE
Sbjct: 526 SSVIGLLERFYDPDEGEVYLDGTNIKEINIHSLRRNIGLVSQEPVLFANSIAENIRYGNE 585
Query: 1480 HATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILL 1659
+AT DQ++EACK ANA+DFI LP+GY T+VGEKGVQ+SGGQKQRIAIARA++K+PKILL
Sbjct: 586 NATMDQIIEACKTANAHDFISALPEGYDTQVGEKGVQMSGGQKQRIAIARAMIKDPKILL 645
Query: 1660 LDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHE 1839
LDEATSALD++ E VQ ++++ GRTTI++AHRLSTI++ D+I V K G IVE G+H
Sbjct: 646 LDEATSALDSQNELLVQQSIEKLMIGRTTIVIAHRLSTIQDADQIAVVKGGAIVEIGTHP 705
Query: 1840 ELMSKQGIFYDMT---------XXXXXXXXXXEAGKD------------IEDTISESAHS 1956
EL + G++ + E+ KD I+ +I
Sbjct: 706 ELYALNGVYTQLVNRQQKGGDDGDKKKKKKSKESSKDESNNNIGPSSISIDKSIQSIGAD 765
Query: 1957 HLXXXXXXXXXXXXXXXIHQLAEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXX 2136
L + ++ +E P + +I K +
Sbjct: 766 SLETSTIGLVNDNDNKKKKKKEKKPQEKSVP---IGRILKLSRGDWPHFLIGLVGATLNG 822
Query: 2137 SVTPVFALVYAEIFNVY-SLPADQM---QANVYFWCGMFVLMGITFFVGFFTSANCLGRC 2304
++ PVF+++++EI ++ D++ N+ W F+L+ + + F C
Sbjct: 823 AIMPVFSIIFSEILGIFQEQDTDELTRRSRNMALW---FILLAVVAALANFIQIYCFTFI 879
Query: 2305 GESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVFT-RLPVVLASI 2481
GE LT LR +F++++RQDI ++D + TG+L AT+A V+ + + RL +++ +I
Sbjct: 880 GEKLTFNLRRLSFESIMRQDIGWFDLTENSTGRLTANLATEATLVQGMTSQRLGLLIQNI 939
Query: 2482 VTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQA 2661
VTI L I F GW+ G EM G + + E G+VAS+A
Sbjct: 940 VTIVAGLVIAFVSGWKLTLVVLACVPVIGFAGKVEMDFFQGFSQKGKEAYAECGQVASEA 999
Query: 2662 VEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLG 2841
+ IRTV S + + + + L++P + + ++ G F FSQ +FF+Y ++ G
Sbjct: 1000 IGGIRTVSSFTCENKILEKFRQCLQKPIQMSFRKSNVSGLSFGFSQCTLFFIYTLTYWYG 1059
Query: 2842 SIFVNQ----QAMQPIDVY-------------------------------RVFFAISFCG 2916
V+ ++ Y RVFFAI
Sbjct: 1060 GKLVDSGEWPAKESTLETYCYNGEYANIGYTDEATCIKSFTTTEGFSMMMRVFFAIIMSA 1119
Query: 2917 QMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKP-ITGNISIRNVFFNYP 3093
+G + +F+PD+ KA+LAA +F LI+ + ID + G P G+I +++ F+YP
Sbjct: 1120 MGVGQSMAFMPDLGKAKLAAVAIFSLIDRVSEIDPFENKGQTLPEFKGDIEFKDIKFSYP 1179
Query: 3094 TRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLN 3273
+R + V QGF L I GK VALVG+SG GKS+++ LLERFYN +G I IDG NI++LN
Sbjct: 1180 SRPNKAVFQGFNLVIPHGKKVALVGNSGGGKSSVISLLERFYNPSQGSITIDGVNIKDLN 1239
Query: 3274 ISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYD 3453
++ LR + +V QEP LF TI ENI YG + T E+VEAAK AN H FI LPD Y
Sbjct: 1240 LNWLRGNMGLVGQEPFLFSGTIFENIIYG-KPDATMDEVVEAAKAANAHTFIESLPDAYH 1298
Query: 3454 THVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRT 3633
T +G+K TQLSGGQKQR+AIARA++R+P VLLLDEATSALDT SEK+VQ ALD +GRT
Sbjct: 1299 TQLGDKFTQLSGGQKQRVAIARAIIRNPKVLLLDEATSALDTVSEKVVQVALDNVSKGRT 1358
Query: 3634 CLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
+VIAHRLST+ ++D+I +V EGK+VE GTH+ L+ ++ Y + Q
Sbjct: 1359 SIVIAHRLSTVIDADLIVVVKEGKVVELGTHETLLAENGFYAELVSRQ 1406
Score = 330 bits (846), Expect = 2e-88
Identities = 211/581 (36%), Positives = 309/581 (52%), Gaps = 36/581 (6%)
Frame = +1
Query: 2146 PVFALVYAEIFNVYSLPADQMQAN--------------VYFWCGMFVLMGITFFVGFFTS 2283
P ++V+ + N +S P + N +Y CG+FV + V F+
Sbjct: 155 PAISIVFGRLMNSFS-PENLADPNFDLVETVTSNAMYFIYIGCGVFVCSYVE--VAFWML 211
Query: 2284 ANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVF-TRL 2460
A GE ++ R K +L+Q+I +YD + + +L TR ++D + ++
Sbjct: 212 A------GERQAVRCRKAYLKAILKQEIGWYDVTK--SSELSTRISSDTLLFQEAIGEKI 263
Query: 2461 PVVLASIVT-ICGALGIGFYYG----------WQXXXXXXXXXXXXXMGGYFEMQMRFGK 2607
L T ICG + +GF G WQ G F +M
Sbjct: 264 GNFLHHTSTFICGFI-VGFVNGKNYNYYLFFCWQLTLVIFALTPLIAAAGAFMTKMMADL 322
Query: 2608 QIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVF 2787
+ +AG VA + + IRTV + + + Y E L+E + K G
Sbjct: 323 TKKGQDAYAKAGGVAEEKIGSIRTVSTFSGEPFEVKRYTERLKEALDIGTKKGIMNGIGI 382
Query: 2788 AFSQSLIFFMYAAAFYLGSIFVNQQAMQPI--------DVYRVFFAISFCGQMIGNTTSF 2943
++F Y+ +F+ G + + P+ DV VFF++ +G +
Sbjct: 383 GLVFLVLFGTYSLSFWYGGKLIVDRKWNPVPDRPWQGGDVLTVFFSVIMGAMALGQASPN 442
Query: 2944 IPDVVKARLAASLLFYLIEHPTPIDSLSDSG--IVKPITGNISIRNVFFNYPTRKDTKVL 3117
+ R AA ++ +++ + ID S G I + + GNI RN+ F+YP+R D K+
Sbjct: 443 VASFANGRGAAFKIYEVVDRNSKIDPFSTEGRSIEETVQGNIEYRNIGFSYPSRPDVKIF 502
Query: 3118 QGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQV 3297
F L IK G TVALVG SG GKS+++GLLERFY+ D+G + +DG NI+ +NI SLR +
Sbjct: 503 NNFNLTIKKGTTVALVGDSGGGKSSVIGLLERFYDPDEGEVYLDGTNIKEINIHSLRRNI 562
Query: 3298 CIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGT 3477
+VSQEP LF +I ENI YG N N T +I+EA K AN H+FI LP+GYDT VGEKG
Sbjct: 563 GLVSQEPVLFANSIAENIRYG-NENATMDQIIEACKTANAHDFISALPEGYDTQVGEKGV 621
Query: 3478 QLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRL 3657
Q+SGGQKQRIAIARA+++ P +LLLDEATSALD+++E +VQ++++ GRT +VIAHRL
Sbjct: 622 QMSGGQKQRIAIARAMIKDPKILLLDEATSALDSQNELLVQQSIEKLMIGRTTIVIAHRL 681
Query: 3658 STIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQR 3780
STIQ++D IA+V G IVE GTH EL + +Y + Q+
Sbjct: 682 STIQDADQIAVVKGGAIVEIGTHPELYALNGVYTQLVNRQQ 722
>gi|283552|pir||S27338 P-glycoprotein C - Caenorhabditis elegans
gi|6811|emb|CAA46191.1| P-glycoprotein C [Caenorhabditis elegans]
Length = 1254
Score = 859 bits (2220), Expect = 0.0
Identities = 475/1250 (38%), Positives = 710/1250 (56%), Gaps = 26/1250 (2%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNP 285
+ +F D +L G + + ++GA P +++ G+ + + S + G
Sbjct: 32 FDVFRDADYKDYILFSGGLILSAVNGALVPFNSLIFEGIANALMEGE-SQYQNGT----- 85
Query: 286 EGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAIL 465
I++ F+SE+ +C+ Y LGV +F SY +C + ER +H +R+ YLK++L
Sbjct: 86 -----INMPWFSSEIKMFCLRYFYLGVALFLCSYFANSCLYTLCERRLHCIRKKYLKSVL 140
Query: 466 RQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTL 645
RQ +WFD+ G LT +++ +E++++G+GDK +LV A F++G +GF+ W +TL
Sbjct: 141 RQDAKWFDETTIGGLTQKMSSGIEKIKDGIGDKVGVLVGGVATFISGVSIGFYMCWQLTL 200
Query: 646 VMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDR 825
VMM PL + S +K + T+ E Y+ AG +A E + IRTV + N E++R
Sbjct: 201 VMMITVPLQLGSMYLSAKHLNRATKNEMSAYSNAGGMANEVIAGIRTVMAFNAQPFEINR 260
Query: 826 FYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVF 1005
+ + L R+ GI K + I F + M++ A+AFWYG+TL G +F VF
Sbjct: 261 YAHQLNEARRMGIRKAIILAICTAFPLMLMFTCMAVAFWYGATLAAAGAV-SSGAVFAVF 319
Query: 1006 FAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFK 1185
+AVL G+ LG A PHL + AR A + +VI+ P+I S EG + + ++G ++F
Sbjct: 320 WAVLIGTRRLGEAAPHLGAITGARLAIHDIFKVIDHEPEIKCTSSEGKIPEKIQGKLTFD 379
Query: 1186 DVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDG 1365
+ F YP+R ++ +LKG+S E+ G+ +ALVG SGCGKST + LL RFY+ G + +DG
Sbjct: 380 GIEFTYPTRPELKILKGVSFEVNPGETVALVGHSGCGKSTSIGLLMRFYNQCAGMIKLDG 439
Query: 1366 VDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKR 1545
+ ++E N+ LR IGIV QEP++F T+ ENI+MG+ T + EACKMANA++FI +
Sbjct: 440 IPIQEYNIRWLRSTIGIVQQEPIIFVATVAENIRMGDVLITDQDIEEACKMANAHEFICK 499
Query: 1546 LPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQ 1725
L D Y T +G VQLSGGQKQR+AIARA+V+ P+ILLLDEATSALDTE+ER VQ ALD+
Sbjct: 500 LSDRYDTVIGAGAVQLSGGQKQRVAIARAIVRKPQILLLDEATSALDTESERMVQTALDK 559
Query: 1726 AQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSK-QGIFYDMTXXXXXXXX 1902
A GRTT+ +AHRLSTIRN + +H+EL+SK GI+ M
Sbjct: 560 ASEGRTTLCIAHRLSTIRN--------------ASTHDELISKDDGIYASMVKAQEIERA 605
Query: 1903 XXEAGKDIEDTISESAH------------------------SHLXXXXXXXXXXXXXXXI 2010
+ D E+ E H + L I
Sbjct: 606 KEDTTLDDEE--DEKTHRSFHRDSVTSDEERELQQSLARDSTRLRQSMISTTTQVPEWEI 663
Query: 2011 HQLAEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYS 2190
EE+ E A S+F IFK+ ++ P F++VY ++F + S
Sbjct: 664 ENAREEMIEEGAMEASLFDIFKYASPEMRNIIISLVFTLIRGFTWPAFSIVYGQLFKILS 723
Query: 2191 LPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIA 2370
D + F+L+ T + S + LG+ GE+++ +LR + F+N+++QD +
Sbjct: 724 AGGDDVSIKALLNSLWFILLAFTGGISTLISGSLLGKAGETMSGRLRMDVFRNIMQQDAS 783
Query: 2371 FYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXX 2547
++DD RH G L +R ATDAPNV+ + RL VL IV++ +G+ FYYGW
Sbjct: 784 YFDDSRHNVGSLTSRLATDAPNVQAAIDQRLAEVLTGIVSLFCGVGVAFYYGWNMAPIGL 843
Query: 2548 XXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCE 2727
+ Q + RD EA ++ ++++ + +TV +L +QE + +
Sbjct: 844 ATELLLVVVQSSVAQYLKFRGQRDMDSAIEASRLVTESISNWKTVQALTKQEYMYDAFTA 903
Query: 2728 YLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAIS 2907
+ P + FA + S + + +A A+ G ++ P V++V A++
Sbjct: 904 ASKSPHRRAIVRGLWQSLSFALAGSFVMWNFAIAYMFGLWLISNNWSTPYTVFQVIEALN 963
Query: 2908 FCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVFFN 3087
+ S+ P+ V+AR++A ++F +I + ID+ +G I GNI++R V+F
Sbjct: 964 MASMSVMLAASYFPEYVRARISAGIMFTMIRQKSVIDNRGLTGDTPTIKGNINMRGVYFA 1023
Query: 3088 YPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRN 3267
YP R+ VL GF + G+TVALVG SGCGKST + L+ER+Y+ G + ID +IR+
Sbjct: 1024 YPNRRRQLVLDGFNMSANFGQTVALVGPSGCGKSTTIQLIERYYDALCGSVKIDDSDIRD 1083
Query: 3268 LNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDG 3447
L++ LR+ + +V QEPTLF+ TI ENI YG N+T ++ +AA +ANIH F++GLPDG
Sbjct: 1084 LSVKHLRDNIALVGQEPTLFNLTIRENITYGL-ENITQDQVEKAATLANIHTFVMGLPDG 1142
Query: 3448 YDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQG 3627
YDT VG G +LSGGQKQR+AIARA+VR P +LLLDEATSALDTESEKIVQEALD A+ G
Sbjct: 1143 YDTSVGASGGRLSGGQKQRVAIARAIVRDPKILLLDEATSALDTESEKIVQEALDKARLG 1202
Query: 3628 RTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
RTC+VIAHRLSTIQN+D I + GK +E+GTH L+ + +Y + E Q
Sbjct: 1203 RTCVVIAHRLSTIQNADKIIVCRNGKAIEEGTHQTLLARRGLYYRLVEKQ 1252
>gi|39594783|emb|CAE70651.1| Hypothetical protein CBG17356
[Caenorhabditis briggsae]
Length = 1265
Score = 854 bits (2206), Expect = 0.0
Identities = 466/1247 (37%), Positives = 717/1247 (57%), Gaps = 25/1247 (2%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F ++ +D LLL+ G V + GA P +++ G+T V ++ Q S++ G
Sbjct: 32 LFRHSDCLDYLLLLGGIVFSSASGALLPFNSLIFEGITNVLMQGQ-SEWQNGT------- 83
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
+ D F++ + YC+ Y +LGV MF +Y+ AC + AER ++ +R++ L+++LRQ
Sbjct: 84 ---FAYDTFSTGIRHYCLLYFLLGVFMFLCTYISNACLYTMAERRLYCIRKHLLRSVLRQ 140
Query: 472 QIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVM 651
QWFD+ G LT +++ +E++++G+GDK +L A F++G +GF+ W +TLVM
Sbjct: 141 DAQWFDENTVGGLTQKMSSGIEKIKDGIGDKIGVLFSGAATFISGVLLGFYMCWQLTLVM 200
Query: 652 MGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFY 831
+ PL + +K + T+ E Y+ AG +A E + IRTV + N E+ R+
Sbjct: 201 LITVPLQLGQMYMSAKHLNRATKNEMSAYSSAGGMANEVIAGIRTVIAFNAQPFEISRYA 260
Query: 832 NALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFA 1011
+ L RQ GI K + + M+ A AFWYG+ ++ + G F VF+A
Sbjct: 261 DKLAEARQMGIRKSIVLASCSAVPLVLMFVLMAGAFWYGA-ILTSFGIATSGTTFGVFWA 319
Query: 1012 VLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDV 1191
VL G+ LG A PH+ + AR A + + +VI++ P+I+ G + + G ++F ++
Sbjct: 320 VLLGTRRLGEAAPHMGAILGARLAINDIFKVIDNEPEINCTKETGRRPEKINGKLNFDNI 379
Query: 1192 HFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVD 1371
F YP+R D+ +LKG+S E+ G+ +ALVG SGCGKST + LL RFY+ G + +DGV
Sbjct: 380 EFTYPTRPDVKILKGVSFEVNPGETVALVGHSGCGKSTSIGLLMRFYNQCAGTIKLDGVP 439
Query: 1372 LREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLP 1551
+ + N+ LR IGIV QEP++F T+ ENI+MG+ T + +AC+ ANA+DFI L
Sbjct: 440 IEDYNIQWLRSTIGIVQQEPIIFLATVSENIRMGDNSITDKDIEDACRQANAHDFIGHLS 499
Query: 1552 DGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQ 1731
DGY T +G VQLSGGQKQR+AIARA+V+ P+ILLLDEATSALDTE+ER VQ ALD+A
Sbjct: 500 DGYNTIIGAGAVQLSGGQKQRVAIARAIVRKPQILLLDEATSALDTESERMVQAALDKAS 559
Query: 1732 AGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXXE 1911
GRTT+ +AHRLSTIRN ++I VF G IVE G+H++L+ + GI+ M +
Sbjct: 560 QGRTTLCIAHRLSTIRNANKILVFDQGLIVEKGTHDQLIRQNGIYASMVRAQEIERAKED 619
Query: 1912 AGKDIEDTISESAHS-----------------------HLXXXXXXXXXXXXXXXIHQLA 2022
+ +D++ E S L +
Sbjct: 620 TVVE-DDSLEEETQSISRRLSTSEDEVRKSKSLLRDSARLSQSMLSVTSQVPDWEVEIAR 678
Query: 2023 EEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVT-PVFALVYAEIFNVYSLPA 2199
EE+ E A SM IF+F W +T P F++VY ++F V++
Sbjct: 679 EEMFEEGAMEASMMDIFRF-AKPEKWNVIIALIVTLIRGITWPAFSVVYGQLFKVFAEGG 737
Query: 2200 DQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYD 2379
+ + N + F+L+ T + F S + LG+ GE+++ +LR FKN+++QD +++D
Sbjct: 738 EDLPTNAFVSSLWFILLAFTSGITTFISGSLLGKTGETMSSRLRLNVFKNIMQQDASYFD 797
Query: 2380 DLRHGTGKLCTRFATDAPNVRYVFT-RLPVVLASIVTICGALGIGFYYGWQXXXXXXXXX 2556
+ +H G L R ATD+ NV+ RL VL ++++ + + F++GW
Sbjct: 798 EPKHNVGNLTARLATDSQNVQAAIDHRLAEVLNGVISLFAGIAVAFWFGWSMAPIGLLTA 857
Query: 2557 XXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLR 2736
+ Q + +D + EA ++ ++++ + +TV +L +QE + + +
Sbjct: 858 LLLVIAQSSVAQYLKYRGPKDMESAIEASRIVTESISNWKTVQALTKQEYMYGAFTTASK 917
Query: 2737 EPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCG 2916
+P FA + S + +A A+ G ++ P V++V A++
Sbjct: 918 KPRQRAFAKGLWQSLSFALAGSFFLWNFAIAYMFGLWLISNNWTTPFAVFQVIEALNMAS 977
Query: 2917 QMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPT 3096
+ S+ P+ V+AR++A ++F +I + ID+ +G I G+IS+R V+F YP
Sbjct: 978 MSVMMAASYFPEYVRARISAGIMFTMIRQKSAIDNRGLTGETPLIKGDISMRGVYFAYPN 1037
Query: 3097 RKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNI 3276
RK +L F + G+TVALVG SGCGKST + L+ER+Y+ G + ID ++R++++
Sbjct: 1038 RKRQLILNNFNMSANFGQTVALVGPSGCGKSTTIQLIERYYDAVCGSVRIDDTDVRDISV 1097
Query: 3277 SSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDT 3456
LR+ + +V QEPTLF+ +I ENI YG NV+ ++I EAAK+ANIHNF++ LP+GYDT
Sbjct: 1098 KHLRDNIALVGQEPTLFNLSIRENITYGL-ENVSQEQIEEAAKLANIHNFVISLPEGYDT 1156
Query: 3457 HVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTC 3636
VG G +LSGGQKQRIAIARA+VR P +LLLDEATSALD+ESEKIVQEALD A+ GRTC
Sbjct: 1157 SVGASGGRLSGGQKQRIAIARAIVRDPKILLLDEATSALDSESEKIVQEALDKARLGRTC 1216
Query: 3637 LVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
+VIAHRLSTIQN+D I + GK +E+GTH L+ + +Y + E Q
Sbjct: 1217 VVIAHRLSTIQNADKIIVCRNGKAIEEGTHQSLLARRGLYYRLVEKQ 1263
Score = 333 bits (853), Expect = 2e-89
Identities = 196/530 (36%), Positives = 295/530 (54%), Gaps = 2/530 (0%)
Frame = +1
Query: 2200 DQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYD 2379
D + +C ++ L+G+ F+ + S CL E +R +++LRQD ++D
Sbjct: 87 DTFSTGIRHYCLLYFLLGVFMFLCTYISNACLYTMAERRLYCIRKHLLRSVLRQDAQWFD 146
Query: 2380 DLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXX 2556
+ + G L + ++ ++ + ++ V+ + T + +GFY WQ
Sbjct: 147 E--NTVGGLTQKMSSGIEKIKDGIGDKIGVLFSGAATFISGVLLGFYMCWQLTLVMLITV 204
Query: 2557 XXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLR 2736
Y + + AG +A++ + IRTV + N Q Y + L
Sbjct: 205 PLQLGQMYMSAKHLNRATKNEMSAYSSAGGMANEVIAGIRTVIAFNAQPFEISRYADKLA 264
Query: 2737 EPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCG 2916
E ++ + + A L+F + A AF+ G+I + + VF+A+
Sbjct: 265 EARQMGIRKSIVLASCSAVPLVLMFVLMAGAFWYGAILTSFGIATSGTTFGVFWAVLLGT 324
Query: 2917 QMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGI-VKPITGNISIRNVFFNYP 3093
+ +G + ++ ARLA + +F +I++ I+ ++G + I G ++ N+ F YP
Sbjct: 325 RRLGEAAPHMGAILGARLAINDIFKVIDNEPEINCTKETGRRPEKINGKLNFDNIEFTYP 384
Query: 3094 TRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLN 3273
TR D K+L+G + ++ G+TVALVGHSGCGKST +GLL RFYNQ G I +DG I + N
Sbjct: 385 TRPDVKILKGVSFEVNPGETVALVGHSGCGKSTSIGLLMRFYNQCAGTIKLDGVPIEDYN 444
Query: 3274 ISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYD 3453
I LR + IV QEP +F T+ ENI G N ++T ++I +A + AN H+FI L DGY+
Sbjct: 445 IQWLRSTIGIVQQEPIIFLATVSENIRMGDN-SITDKDIEDACRQANAHDFIGHLSDGYN 503
Query: 3454 THVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRT 3633
T +G QLSGGQKQR+AIARA+VR P +LLLDEATSALDTESE++VQ ALD A QGRT
Sbjct: 504 TIIGAGAVQLSGGQKQRVAIARAIVRKPQILLLDEATSALDTESERMVQAALDKASQGRT 563
Query: 3634 CLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRI 3783
L IAHRLSTI+N++ I + +G IVEKGTHD+LIR++ IY Q I
Sbjct: 564 TLCIAHRLSTIRNANKILVFDQGLIVEKGTHDQLIRQNGIYASMVRAQEI 613
>gi|12585141|sp|Q9N0V3|AB11_RABIT Bile salt export pump (ATP-binding
cassette, sub-family B, member 11) (Sister of
P-glycoprotein)
gi|7644354|gb|AAF65552.1| liver bile salt export pump [Oryctolagus
cuniculus]
Length = 1321
Score = 849 bits (2193), Expect = 0.0
Identities = 476/1275 (37%), Positives = 729/1275 (56%), Gaps = 46/1275 (3%)
Frame = +1
Query: 88 TVKLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFL---------- 237
+V++ + +F ++ D+ L+ G++ A IHG P + ++ G MT VF+
Sbjct: 42 SVRIGFFQLFRFSSWTDIWLMCMGSLCACIHGIAQPGVLLIFGTMTDVFIDYDTELQELK 101
Query: 238 ---RAQNSDFVVGVD---NVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIA 399
+A ++ +V ++ N N L + SE++++ YY +G+ + T Y+QI
Sbjct: 102 IPGKACVNNTIVWINSSLNQNVTNGTRCGLLDIESEMIRFAGYYAGIGIAVLTTGYIQIC 161
Query: 400 CFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLV 579
+ A + K+R++Y + I+R I W D G L + D ++ + D+ A+ +
Sbjct: 162 FWGIAAAHQIQKMRKSYFRKIMRMGIGWVDCNSVGKLNTPFSVDFNKINDSSADQLAIFI 221
Query: 580 QMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIA 759
Q + + G+ VGF W +TLV++ +PLI L A + S++ T E + YA AG++A
Sbjct: 222 QGMTSPIFGFLVGFSQWWKLTLVIISVSPLIGLGAAIIGLSVSKFTDYELKAYAKAGSVA 281
Query: 760 EETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAF 939
+E SS+RTV + G K+E++R+ L ++ GI K MG G+ ++ YALAF
Sbjct: 282 DEVISSMRTVAAFGGEKKEVERYEKNLVFAQRWGIRKGIVMGFFTGYMWCLIFFCYALAF 341
Query: 940 WYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHP 1119
WYGS L++ + + G + +F +V+ G+ +LG A P L +F R AAS++ I+ P
Sbjct: 342 WYGSKLVLEEGEYSPGALVQIFLSVIIGALNLGNASPCLEAFAAGRAAASSIFETIDRKP 401
Query: 1120 KIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGK 1299
ID S +G ++ +KG+I F +V F YPSR ++ +L +S+ +K G+ ALVG SG GK
Sbjct: 402 IIDCMSEDGYKLERIKGEIEFHNVTFHYPSRPEVKILNNLSMVIKPGEMTALVGPSGAGK 461
Query: 1300 STIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNE 1479
ST + L+ RFY PT+G V ++ D+R ++ LR QIGIV QEPVLF TI E I+ G E
Sbjct: 462 STALQLIHRFYGPTEGMVTVESHDIRSSHIQWLRNQIGIVEQEPVLFFHTIAEKIRYGRE 521
Query: 1480 HATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILL 1659
AT + +++A K ANA +FI LP + T VGE G Q+SGGQKQR+AIARAL++NPKILL
Sbjct: 522 DATMEDLIQAAKEANAYNFIMDLPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILL 581
Query: 1660 LDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHE 1839
LD ATSALD E+E VQ AL + Q G T + VAHR +TIR D I + G VE G+ E
Sbjct: 582 LDMATSALDNESEAMVQEALSKTQHGHTIVSVAHRPATIRTADVIIGCEHGAAVERGTEE 641
Query: 1840 ELMSKQGIFYDMTXXXXXXXXXXEAGKD---IEDTISESAHSH------LXXXXXXXXXX 1992
EL+ ++G+++ + + + ED I E S L
Sbjct: 642 ELLERKGVYFALVTLQSQRNQGDQEENEKDATEDDIPEKTFSRGNYQDSLRASLRQRSKS 701
Query: 1993 XXXXXIHQLAEEVEECKA-----------------PPTSMFKIFKFNGDKVGWXXXXXXX 2121
H+ VE+ K+ P S+ +I K N + +
Sbjct: 702 QLSYLAHEPPMAVEDHKSTHEEDRKDKDLPAQEDIEPASVRRIMKLNAPEWPYMLLGSMG 761
Query: 2122 XXXXXSVTPVFALVYAEIFNVYSLP-ADQMQANVYFWCGMFVLMGITFFVGFFTSANCLG 2298
+VTP++A ++++I +SLP ++ ++ + C +FV +G F F
Sbjct: 762 AAVNGAVTPLYAFLFSQILGTFSLPDKEEQRSQINGICLLFVTLGCVSFFTQFLQGYTFA 821
Query: 2299 RCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLA 2475
+ GE LT +LR F+ +L QDI ++DDLR+ G L TR ATDA V+ +++ +++
Sbjct: 822 KSGELLTKRLRKFGFRAMLGQDIGWFDDLRNSPGALTTRLATDASQVQGATGSQIGMMVN 881
Query: 2476 SIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVAS 2655
S + A+ I F + W+ + G + +M G RD Q LE+AG++ S
Sbjct: 882 SFTNVTVAMIIAFLFSWKLTLGIVCFFPFLALSGALQTKMLTGFASRDKQALEKAGQITS 941
Query: 2656 QAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFY 2835
+A+ +IRTV + ++ +F T+ L +P+ +K A+ YG F FSQ + F +A++
Sbjct: 942 EALSNIRTVAGIGKERKFIETFEAELEKPYKMAIKKANVYGLCFGFSQCITFIANSASYR 1001
Query: 2836 LGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPI 3015
G ++ + + V+RV A+ +G +S+ P KA+++A+ F L++ PI
Sbjct: 1002 YGGYLISNEGLHFSYVFRVISAVVLSATALGRASSYTPSYAKAKISAARFFQLLDRQPPI 1061
Query: 3016 DSLSDSGIV-KPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKST 3192
+ S +G G I + F YP+R D +VL G ++ + +T+A VG SGCGKST
Sbjct: 1062 NVYSSAGEKWDNFQGKIDFVDCKFTYPSRPDIQVLNGLSVSMSPRQTLAFVGSSGCGKST 1121
Query: 3193 IMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTN-R 3369
+ LLERFY+ D G +MIDG + R +NI LR + IVSQEP LF C+I +NI YG N +
Sbjct: 1122 SIQLLERFYDPDHGKVMIDGHDSRKVNIQFLRSNIGIVSQEPVLFACSIKDNIKYGDNTQ 1181
Query: 3370 NVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLL 3549
+ + I+ AAK A +H+F++ LP+ Y+T+VG +G+QLS G+KQRIAIARA+VR P +LL
Sbjct: 1182 EIPMERIIAAAKKAQVHDFVMSLPEKYETNVGSQGSQLSRGEKQRIAIARAIVRDPKILL 1241
Query: 3550 LDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHD 3729
LDEATSALDTESEK VQ ALD A++GRTC+VIAHRLSTIQNSD+IA++S+G ++EKGTH+
Sbjct: 1242 LDEATSALDTESEKTVQVALDKAREGRTCIVIAHRLSTIQNSDIIAVMSQGMVIEKGTHE 1301
Query: 3730 ELIRKSEIYQKFCET 3774
EL+ + Y K T
Sbjct: 1302 ELMVQKGAYYKLVTT 1316
>gi|17569145|ref|NP_509902.1| P-GlycoProtein related (pgp-4)
[Caenorhabditis elegans]
gi|7503247|pir||T22090 hypothetical protein F42E11.1 - Caenorhabditis
elegans
gi|3877005|emb|CAA91463.1| Hypothetical protein F42E11.1
[Caenorhabditis elegans]
Length = 1266
Score = 849 bits (2193), Expect = 0.0
Identities = 464/1250 (37%), Positives = 708/1250 (56%), Gaps = 28/1250 (2%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRA----QNSDFVVGVDNV 279
+F ++ D LLL+ G V + +GA P +++ G+T V ++ QN F
Sbjct: 32 LFRHSGCADYLLLLGGLVLSAANGALLPFNSLIFEGITNVLMKGEAQWQNGTF------- 84
Query: 280 NPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKA 459
D F+S + YC+ Y +LGVLMF +Y AC + AER ++ +R++ L++
Sbjct: 85 --------DYDTFSSGIQHYCLLYFLLGVLMFTCTYFSNACLFTMAERRLYCIRKHLLQS 136
Query: 460 ILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSM 639
+LRQ +WFD+ G LT +++ +E++++G+GDK +LV A F++G +GF+ W +
Sbjct: 137 VLRQDAKWFDENTVGGLTQKMSSGIEKIKDGIGDKIGVLVSGIATFISGVALGFYMCWQL 196
Query: 640 TLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKREL 819
TLVM+ PL + S +K + T+ E Y+ AG +A E + IRTV + N E+
Sbjct: 197 TLVMLVTVPLQLGSMYLSAKHLNRATKNEMSAYSSAGGMANEVIAGIRTVIAFNAQPFEI 256
Query: 820 DRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFT 999
+R+ L R+ GI K + + M+ A AFWYG+ ++ + G F
Sbjct: 257 ERYGAQLAKARKMGIRKAIVLALCSAMPLFLMFVLMAGAFWYGA-ILTSYGVATSGTTFG 315
Query: 1000 VFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDIS 1179
VF+AV+ G+ LG A PH+ + AR A + + +VI+ P+I+ EG D + G +
Sbjct: 316 VFWAVILGTRRLGEAAPHMGAITGARLAVNDIFKVIDHEPEINCTKQEGRRPDKVNGKLV 375
Query: 1180 FKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLI 1359
F ++ F YP+R D+ +LKG+S E+ G+ IALVG SGCGKST + LL RFY+ G + +
Sbjct: 376 FDNIQFTYPTRPDVKILKGVSFEVNPGETIALVGHSGCGKSTSIGLLMRFYNQCAGSIKL 435
Query: 1360 DGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFI 1539
DG+ + + N+ LR IGIV QEP++F T+ EN++MG++ T + AC+ ANA+DFI
Sbjct: 436 DGIPIEDYNIQWLRSTIGIVQQEPIIFLATVAENVRMGDDSITDKDIENACRQANAHDFI 495
Query: 1540 KRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGAL 1719
+L +GY T +G VQLSGGQKQR+AIARA+V+ P+ILLLDEATSALDTE+ER VQ AL
Sbjct: 496 GKLSEGYNTVIGAGAVQLSGGQKQRVAIARAIVRKPQILLLDEATSALDTESERMVQTAL 555
Query: 1720 DQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXX 1899
D+A GRTT+ +AHRLSTIRN +I VF G I E G H++L+ + GI+ +M
Sbjct: 556 DKASEGRTTLCIAHRLSTIRNASKILVFDQGLIPERGIHDQLIRQNGIYANMVRAQEIEK 615
Query: 1900 XXXEAGKDIEDTISESAHS-----------------------HLXXXXXXXXXXXXXXXI 2010
+ +D ++ + E +S +
Sbjct: 616 AKDDTTQDDDELVEEDNYSISRRLSTSEEELRKSKSLLRDSTRFSQSMLSVTSQVPDWEM 675
Query: 2011 HQLAEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYS 2190
EE+ E A SM IF+F + P F++VY ++F V++
Sbjct: 676 ESAREEMIEEGAMEASMMDIFRFAKPEKMNIVIALIFTLIRGITWPAFSVVYGQLFKVFA 735
Query: 2191 LPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIA 2370
+ + N FVL+ +T V F S + LG+ GE+++ +LR + FKN+++QD
Sbjct: 736 EGGEDLPVNALISSLWFVLLAVTSAVTTFISGSLLGKTGETMSSRLRMDVFKNIMQQDAT 795
Query: 2371 FYDDLRHGTGKLCTRFATDAPNVRYVFT-RLPVVLASIVTICGALGIGFYYGWQXXXXXX 2547
++DD +H G L +R ATD+ NV+ RL VL +V++ + + F++GW
Sbjct: 796 YFDDPKHNVGNLTSRLATDSQNVQAAIDHRLAEVLNGVVSLFTGIAVAFWFGWSMAPIGL 855
Query: 2548 XXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCE 2727
+ Q + +D + EA ++ ++++ + +TV +L +QE +
Sbjct: 856 ITALLLVIAQSAVAQYLKYRGPKDMESAIEASRIVTESISNWKTVQALTKQEYMFHAFTA 915
Query: 2728 YLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAIS 2907
+ P FA + S + +A A+ G ++ P V++V A++
Sbjct: 916 ASKNPRKRAFTKGLWQSLSFALAGSFFLWNFAIAYMFGLWLISNNWTTPFAVFQVIEALN 975
Query: 2908 FCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVFFN 3087
+ S+ P+ V+AR++A ++F +I ID+ +G I G+IS++ V+F
Sbjct: 976 MASMSVMMAASYFPEYVRARISAGIMFTMIRQKAKIDNRGLTGETPDIRGDISMKGVYFA 1035
Query: 3088 YPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRN 3267
YP R +L F + + G+TVALVG SGCGKST + L+ER+Y+ G + ID +IR+
Sbjct: 1036 YPNRNRQLILNNFNMSAQFGETVALVGPSGCGKSTSIQLIERYYDAICGAVKIDDHDIRD 1095
Query: 3268 LNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDG 3447
+++ LR + +V QEPTLF+ TI ENI YG NV+ +++ +AA +ANIH+F+ LP+G
Sbjct: 1096 ISVKHLRHNIALVGQEPTLFNLTIRENITYGL-ENVSQEQVEKAATLANIHSFVENLPEG 1154
Query: 3448 YDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQG 3627
YDT VG G +LSGGQKQRIAIARA+VR+P +LLLDEATSALDTESEKIVQEALD A+ G
Sbjct: 1155 YDTSVGASGGRLSGGQKQRIAIARAIVRNPKILLLDEATSALDTESEKIVQEALDKARLG 1214
Query: 3628 RTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
RTC+VIAHRLSTIQN+D I + GK +E+GTH L+ + +Y + E Q
Sbjct: 1215 RTCVVIAHRLSTIQNADKIIVCRNGKAIEEGTHQTLLARRGLYYRLVEKQ 1264
Score = 323 bits (827), Expect = 3e-86
Identities = 190/535 (35%), Positives = 291/535 (53%), Gaps = 3/535 (0%)
Frame = +1
Query: 2200 DQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYD 2379
D + + +C ++ L+G+ F + S CL E +R +++LRQD ++D
Sbjct: 87 DTFSSGIQHYCLLYFLLGVLMFTCTYFSNACLFTMAERRLYCIRKHLLQSVLRQDAKWFD 146
Query: 2380 DLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXX 2556
+ + G L + ++ ++ + ++ V+++ I T + +GFY WQ
Sbjct: 147 E--NTVGGLTQKMSSGIEKIKDGIGDKIGVLVSGIATFISGVALGFYMCWQLTLVMLVTV 204
Query: 2557 XXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLR 2736
Y + + AG +A++ + IRTV + N Q Y L
Sbjct: 205 PLQLGSMYLSAKHLNRATKNEMSAYSSAGGMANEVIAGIRTVIAFNAQPFEIERYGAQLA 264
Query: 2737 EPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCG 2916
+ ++ A A L+F + A AF+ G+I + + VF+A+
Sbjct: 265 KARKMGIRKAIVLALCSAMPLFLMFVLMAGAFWYGAILTSYGVATSGTTFGVFWAVILGT 324
Query: 2917 QMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKP--ITGNISIRNVFFNY 3090
+ +G + + ARLA + +F +I+H I+ G +P + G + N+ F Y
Sbjct: 325 RRLGEAAPHMGAITGARLAVNDIFKVIDHEPEINCTKQEGR-RPDKVNGKLVFDNIQFTY 383
Query: 3091 PTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNL 3270
PTR D K+L+G + ++ G+T+ALVGHSGCGKST +GLL RFYNQ G I +DG I +
Sbjct: 384 PTRPDVKILKGVSFEVNPGETIALVGHSGCGKSTSIGLLMRFYNQCAGSIKLDGIPIEDY 443
Query: 3271 NISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGY 3450
NI LR + IV QEP +F T+ EN+ G + ++T ++I A + AN H+FI L +GY
Sbjct: 444 NIQWLRSTIGIVQQEPIIFLATVAENVRMGDD-SITDKDIENACRQANAHDFIGKLSEGY 502
Query: 3451 DTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGR 3630
+T +G QLSGGQKQR+AIARA+VR P +LLLDEATSALDTESE++VQ ALD A +GR
Sbjct: 503 NTVIGAGAVQLSGGQKQRVAIARAIVRKPQILLLDEATSALDTESERMVQTALDKASEGR 562
Query: 3631 TCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRIVESQ 3795
T L IAHRLSTI+N+ I + +G I E+G HD+LIR++ IY Q I +++
Sbjct: 563 TTLCIAHRLSTIRNASKILVFDQGLIPERGIHDQLIRQNGIYANMVRAQEIEKAK 617
>gi|48094917|ref|XP_394305.1| similar to ENSANGP00000021663 [Apis
mellifera]
Length = 5485
Score = 838 bits (2165), Expect = 0.0
Identities = 478/1292 (36%), Positives = 722/1292 (54%), Gaps = 85/1292 (6%)
Frame = +1
Query: 136 DLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDF---------------VVGV 270
+L+L+ G + + G P+ I G TT+ + + V+G
Sbjct: 3737 ELMLIFGGLIMGTLTGLCIPISTIQYGEFTTLLVDRNMKNHTSTPTLIMKWFGGGKVLGS 3796
Query: 271 DNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNY 450
++ E ++ + V + + L F + + A R + ++R+ +
Sbjct: 3797 NSTYKE-----RMEALYDDSVAFGVSSAALSTFQFVFAVFTVDLLNVAASRQIVRVRKMF 3851
Query: 451 LKAILRQQIQWFDKQQTGNLTARLTD---------------------------------- 528
L+++LRQ + W+D + N +R+TD
Sbjct: 3852 LRSVLRQDMTWYDINTSTNFASRITDGNNLVNNLRDDAVFCHNGDRRGNHGGFDLEDECK 3911
Query: 529 ---------DLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLS 681
DL+++++G+G+K + + +F++ + F Y W +TLV++ AP+IV++
Sbjct: 3912 RDRVDGGAKDLDKMKDGIGEKLGVFTYLMVSFISSIIISFVYGWKLTLVVLSCAPIIVIA 3971
Query: 682 GAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTG 861
A ++K ++ T E Y AG++AEE +IRTV + NG ++E++R+ L +TG
Sbjct: 3972 TAVVAKVQSSLTAQELTAYGQAGSVAEEVLGAIRTVIAFNGEQKEVNRYAEKLIPAEKTG 4031
Query: 862 IVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIIND-----PTFDRGLIFTVFFAVLSGS 1026
I + + G+G G +Y SYA+AFWYG LI+ D + ++ VFF VL+G+
Sbjct: 4032 IKRGMWSGVGGGVMWFIIYISYAIAFWYGVQLILEDRPKEVKEYTPAVLVIVFFGVLAGA 4091
Query: 1027 TSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYP 1206
++G PHL +F ARG+A+ + +V++ P ID S EG + + G+I FK+VHF+YP
Sbjct: 4092 QNMGLTSPHLEAFAVARGSAAAIFQVLDRVPTIDSLSKEGQKLPAVNGEIEFKNVHFQYP 4151
Query: 1207 SRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVN 1386
+RKD+ VL+G++L + G+ +ALVG SGCGKST + L+QR YDP KG+VL+DGVD+ ++N
Sbjct: 4152 ARKDVKVLQGLNLTINRGETVALVGGSGCGKSTCLQLIQRLYDPHKGQVLLDGVDVSKLN 4211
Query: 1387 VHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGT 1566
V LR IG+V QEPVLFD TI ENI+ GN+ T +++++A K ANA+DFI +LP+ Y +
Sbjct: 4212 VQWLRSHIGVVGQEPVLFDTTIRENIRYGNDSITEEEMIKAAKEANAHDFISKLPEAYDS 4271
Query: 1567 RVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTT 1746
VGE+G Q+SGGQKQRIAIARALV+ P ILLLDEATSALD +E VQ ALD A GRTT
Sbjct: 4272 PVGERGSQMSGGQKQRIAIARALVRRPAILLLDEATSALDLHSEATVQRALDAASKGRTT 4331
Query: 1747 IIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXXEAGKDI 1926
I+V HRLSTI N DRI K G +VE G+HEEL++ +Y + +A
Sbjct: 4332 IVVTHRLSTITNADRIVFIKDGQVVEQGTHEELLALGKHYYGLVSADASATARAKATASA 4391
Query: 1927 EDTISE----------------SAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKAPPTS 2058
T++ S HSH +QL E + AP
Sbjct: 4392 AKTVTAAIPKQKPPLKRQFSTLSMHSH-----RLSLAGASETSANQLEEHEKPYDAP--- 4443
Query: 2059 MFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPAD-QMQANVYFWCG 2235
M +IF N + + + P FA+++ E++ V L D +++ +
Sbjct: 4444 MMRIFGLNKPEWPYNIIGCLAAAMVGASFPAFAVLFGEVYYVLGLQDDEEVRRETVNFSI 4503
Query: 2236 MFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTR 2415
+F+++G+ +G F G G +T ++R F +L+Q++ +YD+ + G LC R
Sbjct: 4504 LFLVVGVVTGLGTFLQMYMFGLAGVRMTTRIRKITFAAMLKQEMGWYDEDTNSVGALCAR 4563
Query: 2416 FATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQ 2592
++DA V+ TR+ +L ++ T+ +G+ YY W+ +FE +
Sbjct: 4564 LSSDAGAVQGATGTRVGAILQALSTLVLGIGLSMYYTWKMTLVSVVSIPLVLGAVFFEAR 4623
Query: 2593 MRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHT 2772
+ G+ +++ + +E A ++A +A+ +IRTV SL ++E F YC L
Sbjct: 4624 VMSGQGLQEKKKMEAATRIAIEAISNIRTVASLGKEEAFLQRYCSELDHVAEATRIRQRL 4683
Query: 2773 YGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPD 2952
G VF+ Q+ FF YA + Y G V + + DV +V A+ F M+G +F P+
Sbjct: 4684 RGLVFSCGQTTPFFGYALSLYYGGALVATEGLNYQDVIKVSEALIFGSWMLGQALAFAPN 4743
Query: 2953 VVKARLAASLLFYLIEHPTPIDSLSDS---GIVKPITGNISIRNVFFNYPTRKDTKVLQG 3123
A+++A +F L++ I S DS + G I V F+YPTR + ++LQG
Sbjct: 4744 FNTAKISAGRIFKLLDRVPEIASPPDSEDKDLDWKADGLIQFSKVEFHYPTRPEMQILQG 4803
Query: 3124 FTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCI 3303
L +K G+ VALVG SGCGKST + LL+R Y+ G + +D +I ++++ +LR Q+ +
Sbjct: 4804 LNLIVKPGQMVALVGQSGCGKSTCIQLLQRLYDPISGTVTMDRRDISSVSLRNLRSQLGV 4863
Query: 3304 VSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQ 3480
V QEP LFD TI ENI YG N R V EI+EAAK +NIH+F+ LP GYDT +G KGTQ
Sbjct: 4864 VGQEPVLFDRTIAENIAYGDNFRLVPMDEIIEAAKKSNIHSFVSSLPLGYDTRLGSKGTQ 4923
Query: 3481 LSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLS 3660
LSGGQKQRIAIARALVR+P VLLLDEATSALDT+SEK+VQ ALD A +GRTC+ IAHRL+
Sbjct: 4924 LSGGQKQRIAIARALVRNPRVLLLDEATSALDTQSEKVVQAALDKAMEGRTCITIAHRLA 4983
Query: 3661 TIQNSDVIAIVSEGKIVEKGTHDELIRKSEIY 3756
TI+N+DVI ++ +G + E GTHD+LI +Y
Sbjct: 4984 TIRNADVICVLEKGTVAEMGTHDDLIAADGLY 5015
Score = 93.6 bits (231), Expect = 3e-17
Identities = 91/341 (26%), Positives = 154/341 (44%), Gaps = 13/341 (3%)
Frame = +1
Query: 886 IGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLS--GSTSLGGALPHLA 1059
IG+G+ L + S + +F YG GL ++ + S S SLG L +A
Sbjct: 2485 IGLGYK-LLICLSMSTSFCYGCLYAARKEVQGVGLTWSAMWEESSPGDSMSLGLILLTIA 2543
Query: 1060 SFGTARGAASTVL-RVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRK-DIHVLK 1233
G ++ R NS + + SL V+ + + F V Y + + +I +
Sbjct: 2544 FDGFLYAVIGYLIARYTNSDEESNATSLT---VNEKQTGVRFDGVRKVYNTDQGEIVAVD 2600
Query: 1234 GISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIG 1413
+L+L G+ +L+G +G GK+TI+ +L PT G + ++G + + IG
Sbjct: 2601 DFTLKLSEGEVTSLLGRNGAGKTTIIKMLTGMLAPTTGEICLNGEE-------GCKPDIG 2653
Query: 1414 IVSQEPVLFDGTI--------YENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTR 1569
+ Q+ VL GT+ Y +K E + Q N ++ + L G++
Sbjct: 2654 VCPQDNVLI-GTLTPREHLLFYAKLKRSKEEYANVQ-------RNVDEMLTSLE--LGSQ 2703
Query: 1570 VGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTI 1749
E +LSGG K+R+ +A A + +PK+++LDE + +D A R + +DQ + GRT I
Sbjct: 2704 EHEPVYRLSGGTKRRLCVALAFLGSPKLVILDEPGAGVDPAARRRIWRLIDQHRTGRTVI 2763
Query: 1750 IVAHRLSTIRNV-DRIFVFKAGNIVESGSHEELMSKQGIFY 1869
+ H L + D + V G I+ +GS L G Y
Sbjct: 2764 LSTHHLDEADTLSDTVVVMHKGKILCTGSPLSLKMMHGRGY 2804
Score = 75.1 bits (183), Expect = 1e-11
Identities = 51/202 (25%), Positives = 97/202 (47%), Gaps = 2/202 (0%)
Frame = +1
Query: 3124 FTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCI 3303
FTL + G+ +L+G +G GK+TI+ +L G I ++G+ + + +
Sbjct: 2602 FTLKLSEGEVTSLLGRNGAGKTTIIKMLTGMLAPTTGEICLNGEE-------GCKPDIGV 2654
Query: 3304 VSQEPTLFDC-TIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQ 3480
Q+ L T E++ + + +E + N+ + L G H E +
Sbjct: 2655 CPQDNVLIGTLTPREHLLFYAKLKRSKEEYANVQR--NVDEMLTSLELGSQEH--EPVYR 2710
Query: 3481 LSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLS 3660
LSGG K+R+ +A A + SP +++LDE + +D + + + +D + GRT ++ H L
Sbjct: 2711 LSGGTKRRLCVALAFLGSPKLVILDEPGAGVDPAARRRIWRLIDQHRTGRTVILSTHHLD 2770
Query: 3661 TIQN-SDVIAIVSEGKIVEKGT 3723
SD + ++ +GKI+ G+
Sbjct: 2771 EADTLSDTVVVMHKGKILCTGS 2792
Score = 60.1 bits (144), Expect = 4e-07
Identities = 67/264 (25%), Positives = 121/264 (45%), Gaps = 11/264 (4%)
Frame = +1
Query: 1111 SHPKIDPYSLEGILVDNMKGDISFKDVHFR--YPSRKDIHV-LKGISLELKAGDKIALVG 1281
SH + D S E + V+ D + + V R Y S +V ++ +S+ ++AG L+G
Sbjct: 3404 SHEEDDDVSKERMRVEGGMSDDALQTVKLRKEYSSVYGTNVAVQNLSIGVEAGKCFGLLG 3463
Query: 1282 SSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSL-REQIGIVSQEPVLFDGTIYE 1458
++G GKST +L PT GR+++ G +E+ L ++G Q + DG +
Sbjct: 3464 TNGAGKSTTFRMLTTEIIPTAGRIIVRG---KEIGSGPLCNGEVGYCPQSDGI-DGFL-- 3517
Query: 1459 NIKMGNEHATHDQVVEACKMAN----ANDFIKRLPDGYGTRVGEKGV-QLSGGQKQRIAI 1623
+ H E C ++N +KRL + K V LSGG K+++
Sbjct: 3518 -----SPHQCLTIHGEVCGLSNVPKAVESALKRLD---LLKYAHKRVSSLSGGNKRKLCT 3569
Query: 1624 ARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIV-AHRLSTIRNV-DRIF 1797
A +++ ++L+DE TS +D + V + +T +I+ +H ++ NV +R+
Sbjct: 3570 ALSVMAPVPVVLMDEPTSGMDPATKDLVTKTIKHLTRNQTCVILTSHSVADCENVCNRVG 3629
Query: 1798 VFKAGNIVESGSHEELMSKQGIFY 1869
+ + G+ + L K G Y
Sbjct: 3630 ILAKAGLRCIGTPQHLKHKFGEGY 3653
Score = 53.1 bits (126), Expect = 5e-05
Identities = 44/192 (22%), Positives = 90/192 (45%), Gaps = 6/192 (3%)
Frame = +1
Query: 3115 LQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQ 3294
+Q ++ ++AGK L+G +G GKST +L G I++ G I + + +
Sbjct: 3446 VQNLSIGVEAGKCFGLLGTNGAGKSTTFRMLTTEIIPTAGRIIVRGKEIGSGPLCNGEVG 3505
Query: 3295 VCIVSQEPTLF----DC-TIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTH 3459
C S F C TI +C +N + + A K ++ +
Sbjct: 3506 YCPQSDGIDGFLSPHQCLTIHGEVCGLSN---VPKAVESALKRLDLLKY----------- 3551
Query: 3460 VGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCL 3639
++ + LSGG K+++ A +++ V+L+DE TS +D ++ +V + + + +TC+
Sbjct: 3552 AHKRVSSLSGGNKRKLCTALSVMAPVPVVLMDEPTSGMDPATKDLVTKTIKHLTRNQTCV 3611
Query: 3640 VI-AHRLSTIQN 3672
++ +H ++ +N
Sbjct: 3612 ILTSHSVADCEN 3623
>gi|27368865|emb|CAD59590.1| MDR-like ABC transporter [Oryza sativa
(japonica cultivar-group)]
gi|46485796|gb|AAS98421.1| MDR-like ABC transporter [Oryza sativa
(japonica cultivar-group)]
Length = 1276
Score = 835 bits (2158), Expect = 0.0
Identities = 460/1234 (37%), Positives = 701/1234 (56%), Gaps = 25/1234 (2%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F + G D L++ GT+ AV +GA P + ++ GG+ F A D V V V+
Sbjct: 44 LFAFADGTDAALMLLGTLGAVANGAALPFMTVLFGGLIDAFGGAAGGDVVARVSEVS--- 100
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
+ ++ L V S++Q+AC+ ER ++R YL+ ILRQ
Sbjct: 101 -----------------LQFIYLAVASAAASFIQVACWMITGERQAARIRSLYLRTILRQ 143
Query: 472 QIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLV 648
++ +FDK TG + R++ D +++ +G+K VQ+ FL G+GV F W +TLV
Sbjct: 144 EVAFFDKHTNTGEVVGRMSGDTVLIQDAMGEKVGKFVQLLVTFLGGFGVAFAQGWLLTLV 203
Query: 649 MMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRF 828
M+ P +VLSGA MS +A + Q YA A + E+T SIRTV S G K+ + ++
Sbjct: 204 MLATIPPLVLSGAVMSNVVARMASLGQAAYADASVVVEQTIGSIRTVASFTGEKQAVAKY 263
Query: 829 YNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFF 1008
+L+ +G+ + G+G+G + ++ Y+L WYG+ LI+ + + + V F
Sbjct: 264 SRSLKRAYSSGVREGLAAGVGMGTVMVLLFCGYSLGIWYGAKLIL-EKGYTGAQVMNVIF 322
Query: 1009 AVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKD 1188
AVL+GS +LG A P + +F + AA + IN P+ID YS G +D+++GDI F++
Sbjct: 323 AVLTGSLALGQASPSMKAFAGGQAAAYKMFETINREPEIDAYSATGRKLDDIQGDIEFRN 382
Query: 1189 VHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGV 1368
V+F YP+R D + +G SL +++G +ALVG SG GKST+++L++RFYDP G VLIDGV
Sbjct: 383 VYFSYPTRPDEQIFRGFSLAIQSGTTVALVGQSGSGKSTVISLIERFYDPQLGEVLIDGV 442
Query: 1369 DLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRL 1548
+L+E+ + +R +IG+VSQEP+LF +I +NI G ++AT+ ++ A ++ANA+ FI ++
Sbjct: 443 NLKELQLRWIRSKIGLVSQEPILFAASIIDNIAYGRDNATNQEIRAAAELANASKFIDKM 502
Query: 1549 PDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQA 1728
P G+ T VGE G QLSGGQKQRIAIARA++K+P+ILLLDEATSALDTE+ER VQ ALD+
Sbjct: 503 PQGFATLVGEHGTQLSGGQKQRIAIARAILKDPRILLLDEATSALDTESERIVQEALDRV 562
Query: 1729 QAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXX 1908
+ RTT+IVAHRL+T+RN D I V G+IVE GSH EL+S Y
Sbjct: 563 MSNRTTVIVAHRLTTVRNADTIAVIHQGSIVEKGSHHELISDPDGAYSQLIRLQENSHDS 622
Query: 1909 E-------AGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLA--------------- 2022
E +GK + I S H +
Sbjct: 623 EDANYQNKSGKKSDSGI-RSGKQSFSYQSTPQRSSRDNSNNHSFSVSATPLEIDVQGGSP 681
Query: 2023 EEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPAD 2202
+++ E + ++ N ++ + P+FA++ + + + P
Sbjct: 682 KKIAEETPQEVPLSRLAALNKPEIPVLLLGSVASAVSGVIFPIFAILLSNVIKAFYEPPQ 741
Query: 2203 QMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDD 2382
++ + FW MF++ G +F+ + G L ++R F+ ++ +I ++D
Sbjct: 742 VLKKDAEFWSSMFLVFGAVYFLSLPIGSYLFSVAGCRLIRRIRLMTFEKVVNMEIEWFDH 801
Query: 2383 LRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXX 2559
+ +G + R + DA +R V L +V+ ++ T+ L I F W+
Sbjct: 802 PENSSGSIGARLSADAAKIRGLVGDALQLVVQNLATLVAGLLIAFISNWELSLIILALIP 861
Query: 2560 XXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLRE 2739
+ G+ +M+ G + EEA +VA+ AV IRTV S + +E+ Y
Sbjct: 862 LIGVNGWIQMKFIQGFSADAKMMYEEASQVANDAVSSIRTVASFSAEEKVMDLYKMKCEG 921
Query: 2740 PFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQ 2919
P T ++ A G F S L+F +YAA+FY G+ V + +V+RVF A++
Sbjct: 922 PLRTGIRTAIISGIGFGVSIFLLFGVYAASFYAGARLVEDRKTTFPNVFRVFLALTMAAI 981
Query: 2920 MIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGI-VKPITGNISIRNVFFNYPT 3096
+ +T++ D KA+ A S +F +++ + ID D+G+ ++P+ G+I ++V F YPT
Sbjct: 982 GVSHTSNLTSDSSKAKSAVSSIFAIVDRKSRIDPSDDAGVSLEPLRGDIEFQHVSFRYPT 1041
Query: 3097 RKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNI 3276
R D ++ + L I++GKTVALVG SG GKST + LL+RFY+ D G I++DG +I+ +
Sbjct: 1042 RPDVQIFEDLCLTIQSGKTVALVGESGSGKSTAISLLQRFYDPDAGHILLDGVDIQKFQL 1101
Query: 3277 SSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDT 3456
LR+Q+ +VSQEP LF+ TI NI YG + T +IV +A++AN H FI L GY+T
Sbjct: 1102 RWLRQQMGLVSQEPALFNDTIRANIAYGKEGDATESDIVSSAQLANAHKFISSLHQGYET 1161
Query: 3457 HVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTC 3636
VGE+G QLSGGQKQRIAIARA+V+ P +LLLDEATSALD ESE++VQ+ALD RT
Sbjct: 1162 MVGERGAQLSGGQKQRIAIARAIVKDPKILLLDEATSALDAESERVVQDALDRVMMNRTT 1221
Query: 3637 LVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELI 3738
+++AHRLSTIQ +D+IA+V G I+EKG HD LI
Sbjct: 1222 VIVAHRLSTIQGADMIAVVKNGMIIEKGKHDALI 1255
Score = 379 bits (973), Expect = e-103
Identities = 220/581 (37%), Positives = 337/581 (57%), Gaps = 4/581 (0%)
Frame = +1
Query: 136 DLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDE 315
++ +L+ G+VA+ + G FP+ AI+L + F P+ L + E
Sbjct: 704 EIPVLLLGSVASAVSGVIFPIFAILLSNVIKAFYEP-------------PQVLKKDA--E 748
Query: 316 FNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD-- 489
F S + +LV G + F + + F RL+ ++R + ++ +I+WFD
Sbjct: 749 FWSSM------FLVFGAVYFLSLPIGSYLFSVAGCRLIRRIRLMTFEKVVNMEIEWFDHP 802
Query: 490 KQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPL 669
+ +G++ ARL+ D ++R +GD L+VQ A +AG + F +W ++L+++ PL
Sbjct: 803 ENSSGSIGARLSADAAKIRGLVGDALQLVVQNLATLVAGLLIAFISNWELSLIILALIPL 862
Query: 670 IVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVG 849
I ++G K + + + Y A +A + SSIRTV S + ++ +D + E
Sbjct: 863 IGVNGWIQMKFIQGFSADAKMMYEEASQVANDAVSSIRTVASFSAEEKVMDLYKMKCEGP 922
Query: 850 RQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGST 1029
+TGI GIG G S ++ YA +F+ G+ L+ + T +F VF A+ +
Sbjct: 923 LRTGIRTAIISGIGFGVSIFLLFGVYAASFYAGARLVEDRKTTFPN-VFRVFLALTMAAI 981
Query: 1030 SLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPS 1209
+ + A+ A S++ +++ +IDP G+ ++ ++GDI F+ V FRYP+
Sbjct: 982 GVSHTSNLTSDSSKAKSAVSSIFAIVDRKSRIDPSDDAGVSLEPLRGDIEFQHVSFRYPT 1041
Query: 1210 RKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNV 1389
R D+ + + + L +++G +ALVG SG GKST ++LLQRFYDP G +L+DGVD+++ +
Sbjct: 1042 RPDVQIFEDLCLTIQSGKTVALVGESGSGKSTAISLLQRFYDPDAGHILLDGVDIQKFQL 1101
Query: 1390 HSLREQIGIVSQEPVLFDGTIYENIKMGNE-HATHDQVVEACKMANANDFIKRLPDGYGT 1566
LR+Q+G+VSQEP LF+ TI NI G E AT +V + ++ANA+ FI L GY T
Sbjct: 1102 RWLRQQMGLVSQEPALFNDTIRANIAYGKEGDATESDIVSSAQLANAHKFISSLHQGYET 1161
Query: 1567 RVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTT 1746
VGE+G QLSGGQKQRIAIARA+VK+PKILLLDEATSALD E+ER VQ ALD+ RTT
Sbjct: 1162 MVGERGAQLSGGQKQRIAIARAIVKDPKILLLDEATSALDAESERVVQDALDRVMMNRTT 1221
Query: 1747 IIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMS-KQGIF 1866
+IVAHRLSTI+ D I V K G I+E G H+ L+ K G +
Sbjct: 1222 VIVAHRLSTIQGADMIAVVKNGMIIEKGKHDALIGIKDGAY 1262
>gi|15228695|ref|NP_191774.1| multidrug resistant (MDR) ABC
transporter, putative [Arabidopsis thaliana]
gi|11277353|pir||T48007 P-glycoprotein homolog T17J13.110
[similarity] - Arabidopsis thaliana
gi|6899925|emb|CAB71875.1| P-glycoprotein-like proetin [Arabidopsis
thaliana]
Length = 1292
Score = 826 bits (2133), Expect = 0.0
Identities = 465/1237 (37%), Positives = 696/1237 (55%), Gaps = 22/1237 (1%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F + D++L+I GT+ AV +G GFP++ I+ G + VF + QNS V
Sbjct: 68 LFAFADSFDIILMILGTIGAVGNGLGFPIMTILFGDVIDVFGQNQNSSDV---------- 117
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
+ ++ K + ++ LG+ + +Q++ + ER ++R YL+ ILRQ
Sbjct: 118 ---------SDKIAKVALKFVYLGLGTLVAALLQVSGWMISGERQAGRIRSLYLQTILRQ 168
Query: 472 QIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLV 648
I +FD + TG + R++ D +++ +G+K +Q+ + F+ G+ + F W +TLV
Sbjct: 169 DIAFFDVETNTGEVVGRMSGDTVLIQDAMGEKVGKAIQLVSTFIGGFVIAFTEGWLLTLV 228
Query: 649 MMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRF 828
M+ PL+V+SGA ++ ++ Q +YA A + E+T SIRTV S G K+ + +
Sbjct: 229 MVSSIPLLVMSGAALAIVISKMASRGQTSYAKAAVVVEQTVGSIRTVASFTGEKQAISNY 288
Query: 829 YNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFF 1008
L + G+ + G+G+G N+ ++ +YALA WYG +I+ + + G + + F
Sbjct: 289 NKHLVSAYRAGVFEGASTGLGLGTLNIVIFCTYALAVWYGGKMIL-EKGYTGGQVLIIIF 347
Query: 1009 AVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKD 1188
AVL+GS SLG A P L++F + AA + I P+ID G ++D+++GDI +
Sbjct: 348 AVLTGSMSLGQASPCLSAFAAGQAAAYKMFEAIKRKPEIDASDTTGKVLDDIRGDIELNN 407
Query: 1189 VHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGV 1368
V+F YP+R + + +G SL + +G +ALVG SG GKST+V+L++RFYDP G V IDG+
Sbjct: 408 VNFSYPARPEEQIFRGFSLSISSGSTVALVGQSGSGKSTVVSLIERFYDPQSGEVRIDGI 467
Query: 1369 DLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRL 1548
+L+E + +R +IG+VSQEPVLF +I ENI G E+AT +++ +A ++ANA+ FI +L
Sbjct: 468 NLKEFQLKWIRSKIGLVSQEPVLFTSSIKENIAYGKENATVEEIRKATELANASKFIDKL 527
Query: 1549 PDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQA 1728
P G T VGE G QLSGGQKQRIA+ARA++K+P+ILLLDEATSALD E+ER VQ ALD+
Sbjct: 528 PQGLDTMVGEHGTQLSGGQKQRIAVARAILKDPRILLLDEATSALDAESERIVQEALDRI 587
Query: 1729 QAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXX 1908
RTT++VAHRLST+RN D I V G IVE GSH EL+ Y
Sbjct: 588 MVNRTTVVVAHRLSTVRNADMIAVIHQGKIVEKGSHSELLRDPEGAYSQLIRLQEDTKQT 647
Query: 1909 EAGKDIEDTISE----------SAHSHLXXXXXXXXXXXXXXXIHQLAEEVEE------- 2037
E D + E S L I E + E
Sbjct: 648 EDSTDEQKLSMESMKRSSLRKSSLSRSLSKRSSSFSMFGFPAGIDTNNEAIPEKDIKVST 707
Query: 2038 -CKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQA 2214
K S F++ N ++ + P+F ++ + + + P +Q+++
Sbjct: 708 PIKEKKVSFFRVAALNKPEIPMLILGSIAAVLNGVILPIFGILISSVIKAFFKPPEQLKS 767
Query: 2215 NVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHG 2394
+ FW +F+L+G+ V F G L ++R F+ ++R ++ ++D+ +
Sbjct: 768 DTRFWAIIFMLLGVASMVVFPAQTIFFSIAGCKLVQRIRSMCFEKVVRMEVGWFDETENS 827
Query: 2395 TGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXM 2571
+G + R + DA VR V L + ++ ++ L I F WQ +
Sbjct: 828 SGAIGARLSADAATVRGLVGDALAQTVQNLASVTAGLVIAFVASWQLAFIVLAMLPLIGL 887
Query: 2572 GGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNT 2751
GY M+ G +EA +VA+ AV IRTV S +E+ Y + P T
Sbjct: 888 NGYIYMKFMVGFSAD----AKEASQVANDAVGSIRTVASFCAEEKVMKMYKKKCEGPMRT 943
Query: 2752 NLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGN 2931
++ G F S ++F YAA+FY G+ V+ V+RVFFA++ I
Sbjct: 944 GIRQGIVSGIGFGVSFFVLFSSYAASFYAGARLVDDGKTTFDSVFRVFFALTMAAVAISQ 1003
Query: 2932 TTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDT 3108
++S PD KA AA+ +F +I+ + ID +SG ++ + G+I +R++ F YP+R D
Sbjct: 1004 SSSLSPDSSKASNAAASIFAVIDRESKIDPSDESGRVLDNVKGDIELRHISFKYPSRPDV 1063
Query: 3109 KVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLR 3288
++ Q L I+AGKT+ALVG SG GKST++ LL+RFY+ D G I +DG I+ L + LR
Sbjct: 1064 QIFQDLCLSIRAGKTIALVGESGSGKSTVIALLQRFYDPDSGQITLDGVEIKTLQLKWLR 1123
Query: 3289 EQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGE 3468
+Q +VSQEP LF+ TI NI YG + T EIV AA+++N H FI GL GYDT VGE
Sbjct: 1124 QQTGLVSQEPVLFNETIRANIAYGKGGDATETEIVSAAELSNAHGFISGLQQGYDTMVGE 1183
Query: 3469 KGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIA 3648
+G QLSGGQKQR+AIARA+V+ P VLLLDEATSALD ESE++VQ+ALD RT +V+A
Sbjct: 1184 RGVQLSGGQKQRVAIARAIVKDPKVLLLDEATSALDAESERVVQDALDRVMVNRTTVVVA 1243
Query: 3649 HRLSTIQNSDVIAIVSEGKIVEKGTHDELIR-KSEIY 3756
HRLSTI+N+DVIA+V G IVEKG H+ LI K +Y
Sbjct: 1244 HRLSTIKNADVIAVVKNGVIVEKGKHETLINIKDGVY 1280
>gi|22535563|dbj|BAC10738.1| putative multidrug resistance protein 1
homolog [Oryza sativa (japonica cultivar-group)]
gi|27368857|emb|CAD59586.1| MDR-like ABC transporter [Oryza sativa
(japonica cultivar-group)]
Length = 1274
Score = 823 bits (2125), Expect = 0.0
Identities = 469/1257 (37%), Positives = 709/1257 (56%), Gaps = 31/1257 (2%)
Frame = +1
Query: 94 KLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVD 273
K++ G+F Y G DLLL+ GTVAA+ +G PL+ ++ G + F A N D
Sbjct: 36 KVSFTGLFRYADGTDLLLMAVGTVAALANGVSQPLMTVIFGQVINAFGEATNGDV----- 90
Query: 274 NVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYL 453
L N V+ + + LG+ S++Q+AC+ ER ++R YL
Sbjct: 91 -----------LHRVNQAVLNF----VYLGIATAVVSFLQVACWTMTGERQATRIRSLYL 135
Query: 454 KAILRQQIQWFDKQQT-GNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYS 630
K++LRQ I +FD + T G + +R++ D V++ +G+K +Q+ A F G+ V F
Sbjct: 136 KSVLRQDIAFFDVEMTTGQIVSRMSGDTVLVQDAIGEKVGKFLQLVATFAGGFVVAFVKG 195
Query: 631 WSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHK 810
W ++LVM+ P +V++G +SK +A + Q +Y+ A + E+T +I+TV S NG K
Sbjct: 196 WLLSLVMLACIPPVVIAGGAVSKMLAKISSKGQASYSDAANVVEQTIGAIKTVVSFNGEK 255
Query: 811 RELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGL 990
+ + + + + + + G G+G +SSY LA WYG L+++ + G
Sbjct: 256 QAVASYNKLINKAYKAAVEEGLTNGFGMGSVFFIFFSSYGLAIWYGGKLVVSKG-YSGGD 314
Query: 991 IFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKG 1170
I + FAV++G+ SLG A P +A+F + AA + + I P+IDP + G +++++G
Sbjct: 315 IINILFAVMTGAMSLGNATPCMAAFAEGQSAAYRLFKTIKRKPQIDPDDITGKQLEDIRG 374
Query: 1171 DISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGR 1350
D+ KDV+F YP+R + + G SL + +G +A+VG SG GKST+++L++RFYDP G
Sbjct: 375 DVELKDVYFSYPARPEQLIFDGFSLHVSSGTTMAIVGESGSGKSTVISLVERFYDPQAGE 434
Query: 1351 VLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAN 1530
VLIDG++++ + ++ +R +IG+VSQEP+LF +I +NI G E AT +++ A ++ANA
Sbjct: 435 VLIDGINIKSLRLNWIRGKIGLVSQEPLLFMTSIKDNITYGKEDATIEEIRRAAELANAA 494
Query: 1531 DFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQ 1710
+FI +LPDGY T VG++G QLSGGQKQRIAIARA++KNPKILLLDEATSALD E+ER VQ
Sbjct: 495 NFIDKLPDGYDTMVGQRGAQLSGGQKQRIAIARAILKNPKILLLDEATSALDVESERIVQ 554
Query: 1711 GALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXX 1890
AL++ RTT++VAHRL+T+RN D I V + G IVE G H+EL+ Y
Sbjct: 555 EALNRIMVDRTTLVVAHRLTTVRNADCISVVQQGKIVEQGPHDELVMNPNGVYSQLIRLQ 614
Query: 1891 XXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLA---------------- 2022
E D + S S L H LA
Sbjct: 615 ETHEEEEKKLDHHISDSRSKSRSLSFKRSISRDSAGNSSRHSLALPFGLPGSVELLEGND 674
Query: 2023 ----EEVE-------ECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYA 2169
E+ E + KAP + ++ + N +V + P+F ++ +
Sbjct: 675 STVGEQTEQGGDGEVQQKAP---IGRLARLNKPEVPILLLATLAAGVHGVLFPMFGVMIS 731
Query: 2170 EIFNVYSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKN 2349
+ PAD+++ + FW M V++GI + G G L ++R +F++
Sbjct: 732 NAIKTFFEPADKLKKDASFWGLMCVVLGIISIISIPVEYFMFGIAGGKLVERVRALSFRS 791
Query: 2350 LLRQDIAFYDDLRHGTGKLCTRFATDAPNV-RYVFTRLPVVLASIVTICGALGIGFYYGW 2526
++ Q++A++DD R+ +G L R + DA NV R V L + + + T+ + I W
Sbjct: 792 IIHQEVAWFDDPRNSSGALGARLSVDALNVRRLVGDNLALAVQVVSTLITGIVIAMIADW 851
Query: 2527 QXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQ 2706
+ + GY +++ G L E+A +VA+ AV IRTV S +++
Sbjct: 852 KLTLIILCVIPLVGLQGYAQVKFLKGFSEDAKMLYEDASQVATDAVSSIRTVASFCSEKR 911
Query: 2707 FHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVY 2886
Y N ++ G F FS +++ Y FY+G+ FV DV+
Sbjct: 912 VMTMYDNKCEASKNQGVRTGMVGGLGFGFSFLMLYLTYGLCFYVGAQFVRHNKTTFGDVF 971
Query: 2887 RVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNI 3063
+VFFA+ I T++ D KA+ +A +F L++ + IDS SD G + + GNI
Sbjct: 972 KVFFALVLATIGISQTSAMASDSTKAKDSAISIFALLDRKSQIDSSSDEGRTLANVKGNI 1031
Query: 3064 SIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIM 3243
R+V F YPTR D ++ FTL I +GKTVALVG SG GKST + LLERFYN + G I+
Sbjct: 1032 DFRHVSFKYPTRPDVQIFSDFTLHIPSGKTVALVGESGSGKSTAIALLERFYNPESGTIL 1091
Query: 3244 IDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHN 3423
+D I+NL ++ LR+Q+ +V QEP LF+ TI NI YG + +VT +E+++AAK +N H
Sbjct: 1092 LDEVEIKNLKVNWLRDQMGLVGQEPVLFNDTIRANIAYGKHGDVTEEELIKAAKASNAHE 1151
Query: 3424 FILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQE 3603
FI LP GYDT VGE+G QLSGGQKQR+AIARA+++ P +LLLDEATSALD ESE+IVQ+
Sbjct: 1152 FISSLPQGYDTTVGERGVQLSGGQKQRVAIARAILKDPKILLLDEATSALDAESERIVQD 1211
Query: 3604 ALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIR-KSEIYQKFCE 3771
ALD GRT +++AHRLSTI+ +D+IA++ +G I EKG H+ L+ K +Y E
Sbjct: 1212 ALDNVMVGRTTIIVAHRLSTIKGADIIAVLKDGAIAEKGRHEALMNIKDGVYASLVE 1268
Score = 324 bits (831), Expect = 9e-87
Identities = 191/522 (36%), Positives = 294/522 (55%), Gaps = 3/522 (0%)
Frame = +1
Query: 2239 FVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRF 2418
FV +GI V F C GE ++R K++LRQDIAF+D + TG++ +R
Sbjct: 101 FVYLGIATAVVSFLQVACWTMTGERQATRIRSLYLKSVLRQDIAFFD-VEMTTGQIVSRM 159
Query: 2419 ATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQM 2595
+ D V+ + ++ L + T G + F GW + G +M
Sbjct: 160 SGDTVLVQDAIGEKVGKFLQLVATFAGGFVVAFVKGWLLSLVMLACIPPVVIAGGAVSKM 219
Query: 2596 RFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTY 2775
+ +A V Q + I+TV S N ++Q +Y + + + + ++ T
Sbjct: 220 LAKISSKGQASYSDAANVVEQTIGAIKTVVSFNGEKQAVASYNKLINKAYKAAVEEGLTN 279
Query: 2776 GAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDV 2955
G + F Y A + G V + D+ + FA+ +GN T +
Sbjct: 280 GFGMGSVFFIFFSSYGLAIWYGGKLVVSKGYSGGDIINILFAVMTGAMSLGNATPCMAAF 339
Query: 2956 VKARLAASLLFYLIEHPTPIDSLSDSGI-VKPITGNISIRNVFFNYPTRKDTKVLQGFTL 3132
+ + AA LF I+ ID +G ++ I G++ +++V+F+YP R + + GF+L
Sbjct: 340 AEGQSAAYRLFKTIKRKPQIDPDDITGKQLEDIRGDVELKDVYFSYPARPEQLIFDGFSL 399
Query: 3133 DIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQ 3312
+ +G T+A+VG SG GKST++ L+ERFY+ G ++IDG NI++L ++ +R ++ +VSQ
Sbjct: 400 HVSSGTTMAIVGESGSGKSTVISLVERFYDPQAGEVLIDGINIKSLRLNWIRGKIGLVSQ 459
Query: 3313 EPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGG 3492
EP LF +I +NI YG + T +EI AA++AN NFI LPDGYDT VG++G QLSGG
Sbjct: 460 EPLLFMTSIKDNITYG-KEDATIEEIRRAAELANAANFIDKLPDGYDTMVGQRGAQLSGG 518
Query: 3493 QKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQN 3672
QKQRIAIARA++++P +LLLDEATSALD ESE+IVQEAL+ RT LV+AHRL+T++N
Sbjct: 519 QKQRIAIARAILKNPKILLLDEATSALDVESERIVQEALNRIMVDRTTLVVAHRLTTVRN 578
Query: 3673 SDVIAIVSEGKIVEKGTHDELI-RKSEIYQKFCETQRIVESQ 3795
+D I++V +GKIVE+G HDEL+ + +Y + Q E +
Sbjct: 579 ADCISVVQQGKIVEQGPHDELVMNPNGVYSQLIRLQETHEEE 620
>gi|15226477|ref|NP_182223.1| multidrug resistant (MDR) ABC
transporter, putative [Arabidopsis thaliana]
gi|7442647|pir||T02187 probable ABC transporter [imported] -
Arabidopsis thaliana
gi|3522943|gb|AAC34225.1| putative ABC transporter [Arabidopsis
thaliana]
Length = 1286
Score = 823 bits (2125), Expect = 0.0
Identities = 465/1248 (37%), Positives = 698/1248 (55%), Gaps = 31/1248 (2%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNP 285
Y +F + D LL+I GT+ ++ +G GFPL+ ++ G + F Q +
Sbjct: 49 YKLFAFADSFDFLLMILGTLGSIGNGLGFPLMTLLFGDLIDAFGENQTNT---------- 98
Query: 286 EGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAIL 465
+V K + ++ LG+ F +++Q++ + ER ++R YLK IL
Sbjct: 99 -----------TDKVSKVALKFVWLGIGTFAAAFLQLSGWMISGERQAARIRSLYLKTIL 147
Query: 466 RQQIQWFD-KQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMT 642
RQ I +FD TG + R++ D +++ +G+K +Q+ A F+ G+ + F W +T
Sbjct: 148 RQDIAFFDIDTNTGEVVGRMSGDTVLIQDAMGEKVGKAIQLLATFVGGFVIAFVRGWLLT 207
Query: 643 LVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELD 822
LVM+ PL+V++GA ++ +A Q YA A + E+T SIRTV S G K+ +
Sbjct: 208 LVMLSSIPLLVMAGALLAIVIAKTASRGQTAYAKAATVVEQTIGSIRTVASFTGEKQAIS 267
Query: 823 RFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTV 1002
+ L + G+++ G+G+G L ++ SYALA WYG LI+ D + G + +
Sbjct: 268 NYNKHLVTAYKAGVIEGGSTGLGLGTLFLVVFCSYALAVWYGGKLIL-DKGYTGGQVLNI 326
Query: 1003 FFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISF 1182
AVL+GS SLG P L++F + AA + I P ID YS G ++D++KGDI
Sbjct: 327 IIAVLTGSMSLGQTSPCLSAFAAGQAAAYKMFETIERRPNIDSYSTNGKVLDDIKGDIEL 386
Query: 1183 KDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLID 1362
KDV+F YP+R D + +G SL + +G +ALVG SG GKST+V+L++RFYDP G VLID
Sbjct: 387 KDVYFTYPARPDEQIFRGFSLFISSGTTVALVGQSGSGKSTVVSLIERFYDPQAGDVLID 446
Query: 1363 GVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIK 1542
G++L+E + +R +IG+VSQEPVLF +I +NI G E AT +++ A ++ANA+ F+
Sbjct: 447 GINLKEFQLKWIRSKIGLVSQEPVLFTASIKDNIAYGKEDATTEEIKAAAELANASKFVD 506
Query: 1543 RLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALD 1722
+LP G T VGE G QLSGGQKQRIA+ARA++K+P+ILLLDEATSALD E+ER VQ ALD
Sbjct: 507 KLPQGLDTMVGEHGTQLSGGQKQRIAVARAILKDPRILLLDEATSALDAESERVVQEALD 566
Query: 1723 QAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELM-SKQGIFYDMTXXXXXXX 1899
+ RTT++VAHRLST+RN D I V G IVE GSH EL+ +G + +
Sbjct: 567 RIMVNRTTVVVAHRLSTVRNADMIAVIHQGKIVEKGSHTELLKDPEGAYSQLIRLQEEKK 626
Query: 1900 XXXEAGKDIEDTISES------AHSHLXXXXXXXXXXXXXXXIHQL-------------- 2019
A ++ + + ES S L H
Sbjct: 627 SDENAAEEQKMSSIESFKQSSLRKSSLGRSLSKGGSSRGNSSRHSFNMFGFPAGIDGNVV 686
Query: 2020 -AEEVEECKAPPT-----SMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFN 2181
+E ++ P T S+F+I N ++ + P+F ++ + +
Sbjct: 687 QDQEEDDTTQPKTEPKKVSIFRIAALNKPEIPVLILGSISAAANGVILPIFGILISSVIK 746
Query: 2182 VYSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQ 2361
+ P +++ + FW +F+++G + + G L ++R F+ ++
Sbjct: 747 AFFQPPKKLKEDTSFWAIIFMVLGFASIIAYPAQTFFFAIAGCKLVQRIRSMCFEKVVHM 806
Query: 2362 DIAFYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXX 2538
++ ++D+ + +G + R + DA +R V L + ++ +I L I F WQ
Sbjct: 807 EVGWFDEPENSSGTIGARLSADAATIRGLVGDSLAQTVQNLSSILAGLIIAFLACWQLAF 866
Query: 2539 XXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFT 2718
+ G+ M+ G ++ EA +VA+ AV IRTV S +++
Sbjct: 867 VVLAMLPLIALNGFLYMKFMKGFSADAKKMYGEASQVANDAVGSIRTVASFCAEDKVMNM 926
Query: 2719 YCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFF 2898
Y + P ++ G F FS ++F YAA+FY+G+ V+ V+RVFF
Sbjct: 927 YSKKCEGPMKNGIRQGIVSGIGFGFSFFVLFSSYAASFYVGARLVDDGKTTFDSVFRVFF 986
Query: 2899 AISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRN 3075
A++ I ++S PD KA +AA+ +F +++ + ID +SG ++ + G+I +R+
Sbjct: 987 ALTMAAMAISQSSSLSPDSSKADVAAASIFAIMDRESKIDPSVESGRVLDNVKGDIELRH 1046
Query: 3076 VFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGD 3255
V F YP R D ++ Q L I+AGKTVALVG SG GKST++ LL+RFY+ D G I +DG
Sbjct: 1047 VSFKYPARPDVQIFQDLCLSIRAGKTVALVGESGSGKSTVIALLQRFYDPDSGEITLDGV 1106
Query: 3256 NIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILG 3435
I++L + LR+Q +VSQEP LF+ TI NI YG + + EIV +A+++N H FI G
Sbjct: 1107 EIKSLRLKWLRQQTGLVSQEPILFNETIRANIAYGKGGDASESEIVSSAELSNAHGFISG 1166
Query: 3436 LPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDA 3615
L GYDT VGE+G QLSGGQKQR+AIARA+V+ P VLLLDEATSALD ESE++VQ+ALD
Sbjct: 1167 LQQGYDTMVGERGIQLSGGQKQRVAIARAIVKDPKVLLLDEATSALDAESERVVQDALDR 1226
Query: 3616 AKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIR-KSEIY 3756
RT +V+AHRLSTI+N+DVIA+V G IVEKG HD LI K +Y
Sbjct: 1227 VMVNRTTIVVAHRLSTIKNADVIAVVKNGVIVEKGKHDTLINIKDGVY 1274
>gi|27368859|emb|CAD59587.1| MDR-like ABC transporter [Oryza sativa
(japonica cultivar-group)]
Length = 1264
Score = 814 bits (2103), Expect = 0.0
Identities = 467/1244 (37%), Positives = 712/1244 (56%), Gaps = 28/1244 (2%)
Frame = +1
Query: 94 KLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVD 273
K+ + +F Y +D+LL++ GTV A+ +G PL+ ++ G + F
Sbjct: 30 KVPLFSLFRYADRLDVLLMVVGTVGALGNGISQPLMTVLFGNVINSF------------- 76
Query: 274 NVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYL 453
N G V S V K + ++ LG+ S++Q++C+ ER ++R YL
Sbjct: 77 GANTSGSVLRS-------VTKVVLNFIYLGIGTSVASFLQVSCWTMAGERQSARIRSLYL 129
Query: 454 KAILRQQIQWFDKQQT-GNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYS 630
KA+LRQ I +FD + T G +R++ D ++ LG+K LV++ ++F+ G+ + F
Sbjct: 130 KAVLRQDITFFDTEMTTGEAVSRMSSDTLLIQGALGEKGGKLVELLSSFIGGFIIAFTRG 189
Query: 631 WSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHK 810
W +TLVM+ PLI ++ A ++++ + Q +Y+ AG E+T SIRTV S NG K
Sbjct: 190 WLLTLVMLTSLPLIAIASAVSAQALTRVSSKRQTSYSDAGDTVEQTIGSIRTVVSFNGEK 249
Query: 811 RELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGL 990
+ + + N ++ + I + G G+G ++ SY LAFWYG LII + + G
Sbjct: 250 KAIAMYRNFIKKSYKATIEEGIITGFGMGSVMCVVFGSYGLAFWYGGKLII-EKGYTGGK 308
Query: 991 IFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKG 1170
I T+ FAVL+G++SLG A P +A+ + AA + + I P+ID G+++++M G
Sbjct: 309 IMTILFAVLTGASSLGNATPAVAAVVEGQSAAYNLFKTIERKPEIDSDDNNGMVLEDMNG 368
Query: 1171 DISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGR 1350
DI KDV+FRYP+R + +L G+SL++ +G +A+VG SG GKST+++L++RFYDP G
Sbjct: 369 DIELKDVYFRYPARPEQLILDGLSLQVASGTTMAIVGESGSGKSTVISLVERFYDPQSGE 428
Query: 1351 VLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAN 1530
VLIDG+ ++++ + +R +IG+VSQEP+LF +I +NI G + AT +++ A ++ANA
Sbjct: 429 VLIDGISIKKLRLDWIRGKIGLVSQEPLLFMASIKDNIIYGKKDATLEEIKRAAELANAA 488
Query: 1531 DFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQ 1710
+FI +LP+GY T VG++G QLSGGQKQRIAIARA++K+PKILLLDEATSALD E+ER VQ
Sbjct: 489 NFIDKLPNGYDTLVGQRGTQLSGGQKQRIAIARAILKDPKILLLDEATSALDVESERIVQ 548
Query: 1711 GALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXX 1890
AL++ RTT++VAHRLST+RNVD I V + G IVE G H+ L+ Y +
Sbjct: 549 EALNRMMVERTTLVVAHRLSTVRNVDCITVVRKGKIVEQGPHDALVKDPDGAY--SQLIR 606
Query: 1891 XXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXX-----------XXIHQLAEEVEE 2037
+ + D+ S+S IH+ E+
Sbjct: 607 LQETHRDERHKLPDSRSKSTSLSFRRSRTKDFLSKSNRYSFKSPLGLPVDIHEDGMTSEQ 666
Query: 2038 CKA-----------PPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNV 2184
K T ++F N +V + P++ ++ +
Sbjct: 667 QKVDHSDNSDSKAIKKTPFGRLFNLNKPEVPVLLLGSIAASVHGVILPLYGIIMPGVLKS 726
Query: 2185 YSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQD 2364
+ P DQ++ + FW M V++G+ + G G L ++R +F+ ++ Q+
Sbjct: 727 FYEPPDQLRKDSRFWALMSVVLGVACLISIPAEYFLFGIAGGKLIQRVRTLSFQRIMHQE 786
Query: 2365 IAFYDDLRHGTGKLCTRFATDAPNV-RYVFTRLPVVLASIVTICGALGIGFYYGWQXXXX 2541
+A++D + +G L TR + DA NV R V L +++ ++ T+ I F W+
Sbjct: 787 VAWFDKPSNSSGALGTRLSVDALNVRRLVGDNLALIVQAVATLITGFAIAFAADWRLALI 846
Query: 2542 XXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTY 2721
GY +++ G ++ E+A +VA+ AV IRTV S +++ Y
Sbjct: 847 ITCVIPLVGAQGYAQVKFLKGFSEESKEMYEDANQVAADAVGSIRTVASFCSEKRVVAIY 906
Query: 2722 ---CEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRV 2892
CE LR+ ++ G +FS +++ Y FY+G+ FV+Q DV++V
Sbjct: 907 NKKCEALRK---QGIRSGIVGGIGLSFSNLMLYLTYGLCFYVGAKFVSQGKTTFSDVFKV 963
Query: 2893 FFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISI 3069
FFA+ + +++ + KAR +A +F +I+ + IDS SD G I++ +TG+I
Sbjct: 964 FFALVLAAVGVSQSSALSTNATKARDSAISIFSIIDRKSRIDSSSDEGAIMENVTGSIDF 1023
Query: 3070 RNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMID 3249
NV F YP+R D ++ FTL I + KT+ALVG SG GKSTI+ LLERFY+ D G I +D
Sbjct: 1024 NNVSFKYPSRPDVQIFSDFTLHIPSQKTIALVGESGSGKSTIIALLERFYDPDSGNISLD 1083
Query: 3250 GDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFI 3429
G IR+L +S LR+Q+ +V QEP LF+ TI NI YG + VT +EI AK AN H F+
Sbjct: 1084 GVEIRSLKVSWLRDQMGLVGQEPVLFNDTIRANITYGKHSEVTEEEITAVAKAANAHEFV 1143
Query: 3430 LGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEAL 3609
LP GYDT VGEKG QLSGGQKQR+AIARA+++ P +LLLDEATSALD ESE++VQ+AL
Sbjct: 1144 SSLPQGYDTVVGEKGVQLSGGQKQRVAIARAILKDPKILLLDEATSALDAESERVVQDAL 1203
Query: 3610 DAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIR 3741
D RT +V+AHRLSTI+ +D+IA++ EGKI EKG H+ L+R
Sbjct: 1204 DRVMVNRTTIVVAHRLSTIKGADMIAVLKEGKIAEKGKHEALLR 1247
Score = 392 bits (1006), Expect = e-107
Identities = 223/589 (37%), Positives = 327/589 (54%), Gaps = 3/589 (0%)
Frame = +1
Query: 91 VKLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGV 270
+K T +G + ++ +L+ G++AA +HG PL I++ G+ F
Sbjct: 680 IKKTPFGRLFNLNKPEVPVLLLGSIAASVHGVILPLYGIIMPGVLKSFYEPP-------- 731
Query: 271 DNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNY 450
D+ + + + +VLGV + + F +L+ ++R
Sbjct: 732 -------------DQLRKDSRFWALMSVVLGVACLISIPAEYFLFGIAGGKLIQRVRTLS 778
Query: 451 LKAILRQQIQWFDK--QQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFF 624
+ I+ Q++ WFDK +G L RL+ D VR +GD AL+VQ A + G+ + F
Sbjct: 779 FQRIMHQEVAWFDKPSNSSGALGTRLSVDALNVRRLVGDNLALIVQAVATLITGFAIAFA 838
Query: 625 YSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNG 804
W + L++ PL+ G K + + +E Y A +A + SIRTV S
Sbjct: 839 ADWRLALIITCVIPLVGAQGYAQVKFLKGFSEESKEMYEDANQVAADAVGSIRTVASFCS 898
Query: 805 HKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDR 984
KR + + E R+ GI GIG+ FSNL +Y +Y L F+ G+ + T
Sbjct: 899 EKRVVAIYNKKCEALRKQGIRSGIVGGIGLSFSNLMLYLTYGLCFYVGAKFVSQGKTTFS 958
Query: 985 GLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNM 1164
+F VFFA++ + + + + AR +A ++ +I+ +ID S EG +++N+
Sbjct: 959 D-VFKVFFALVLAAVGVSQSSALSTNATKARDSAISIFSIIDRKSRIDSSSDEGAIMENV 1017
Query: 1165 KGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTK 1344
G I F +V F+YPSR D+ + +L + + IALVG SG GKSTI+ LL+RFYDP
Sbjct: 1018 TGSIDFNNVSFKYPSRPDVQIFSDFTLHIPSQKTIALVGESGSGKSTIIALLERFYDPDS 1077
Query: 1345 GRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMG-NEHATHDQVVEACKMA 1521
G + +DGV++R + V LR+Q+G+V QEPVLF+ TI NI G + T +++ K A
Sbjct: 1078 GNISLDGVEIRSLKVSWLRDQMGLVGQEPVLFNDTIRANITYGKHSEVTEEEITAVAKAA 1137
Query: 1522 NANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAER 1701
NA++F+ LP GY T VGEKGVQLSGGQKQR+AIARA++K+PKILLLDEATSALD E+ER
Sbjct: 1138 NAHEFVSSLPQGYDTVVGEKGVQLSGGQKQRVAIARAILKDPKILLLDEATSALDAESER 1197
Query: 1702 EVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELM 1848
VQ ALD+ RTTI+VAHRLSTI+ D I V K G I E G HE L+
Sbjct: 1198 VVQDALDRVMVNRTTIVVAHRLSTIKGADMIAVLKEGKIAEKGKHEALL 1246
>gi|22026798|ref|NP_523740.2| CG8523-PA [Drosophila melanogaster]
gi|21645421|gb|AAF58271.2| CG8523-PA [Drosophila melanogaster]
Length = 1287
Score = 813 bits (2099), Expect = 0.0
Identities = 464/1253 (37%), Positives = 709/1253 (56%), Gaps = 25/1253 (1%)
Frame = +1
Query: 94 KLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVD 273
+++ + +F Y D L + G ++AV G P +++ G + + G
Sbjct: 44 QVSYFQLFRYATKKDRALYVIGLLSAVATGLTTPANSLIFGNLANDMIDLGGL-LESGKS 102
Query: 274 NVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYL 453
+ + + LD+ V ++ + +G++M SY+ I CF A + +R +
Sbjct: 103 YRADDAISTLLLDK----VRQFSLQNTYIGIIMLVCSYLSITCFNYAAHSQILTIRSKFF 158
Query: 454 KAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSW 633
++IL Q ++W+D Q+G + +R+ +DL ++ +GL +K + V AF+ + F W
Sbjct: 159 RSILHQDMKWYDFNQSGEVASRMNEDLSKMEDGLAEKVVMFVHYLVAFVGSLVLAFVKGW 218
Query: 634 SMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKR 813
++LV + PL ++ ++ + + + E YA A +AE S IRTV + G +
Sbjct: 219 QLSLVCLTSLPLTFIAMGLVAVATSRLAKKEVTMYAGAAVVAEGALSGIRTVKAFEGEAK 278
Query: 814 ELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLII---NDPTF-- 978
E+ + + + I + + GIG G +Y+SYALAFWYG L+I ++P +
Sbjct: 279 EVAAYKERVVAAKILNIKRNMFSGIGFGLLWFFIYASYALAFWYGVGLVIKGYHEPAYEN 338
Query: 979 -DRGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILV 1155
D G + TVFF+V+ GS ++G A P++ +FG A+GA + V +I P+I+P EG +
Sbjct: 339 YDAGTMITVFFSVMMGSMNIGMAAPYIEAFGIAKGACAKVFHIIEQIPEINPIDGEGKKL 398
Query: 1156 DNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYD 1335
+ I FK+V F+YP+R ++ +L ++L++ G +ALVG SGCGKST + L+QRFYD
Sbjct: 399 NEPLTTIEFKEVEFQYPTRPEVSILNKLNLKIHRGQTVALVGPSGCGKSTCIQLVQRFYD 458
Query: 1336 PTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACK 1515
P G +L +G +L++++++ LR +IG+V QEP+LF +IYENI+ G E AT +++ A
Sbjct: 459 PQAGNLLFNGTNLKDLDINWLRSRIGVVGQEPILFATSIYENIRYGREDATREEIEAAAA 518
Query: 1516 MANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEA 1695
ANA FIK+LP GY T VGE+G QLSGGQKQRIAIARAL+++P+ILLLDEATSALDT +
Sbjct: 519 AANAAIFIKKLPKGYDTLVGERGAQLSGGQKQRIAIARALIRDPEILLLDEATSALDTAS 578
Query: 1696 EREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM 1875
E +VQ AL++ AGRTTIIVAHRLST+R DRI V G +VESG+H+ELM + ++++
Sbjct: 579 EAKVQAALEKVSAGRTTIIVAHRLSTVRRADRIVVINKGEVVESGTHQELMELKDHYFNL 638
Query: 1876 TXXXXXXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEV-------- 2031
+ G+D +S + + E+V
Sbjct: 639 V--------TTQLGEDDGSVLSPTGDIYKNFDIKDEDEEEIKVLSEDEDEDVMVTDEKNK 690
Query: 2032 ----EECKAP--PTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSL 2193
++ K P M ++ K N + P+FA+++ I + S+
Sbjct: 691 KKKKKKVKDPNEVKPMLEVMKMNKPEWLQIAVGCISSVIMGCAMPIFAVLFGSILQILSV 750
Query: 2194 PADQ--MQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDI 2367
+ ++ N + F++ GI + F G GE LT +LR F+ +LRQ++
Sbjct: 751 KDNDQYVRENSNQYSLYFLIAGIVVGIATFLQIYFFGIAGERLTERLRGLMFEAMLRQEV 810
Query: 2368 AFYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXX 2544
A++DD +GTG LC R + DA V+ R+ ++ SI T+ + + YY W
Sbjct: 811 AWFDDKANGTGSLCARLSGDAAAVQGATGQRIGTIVQSISTLALGIALSMYYEWSLGLVA 870
Query: 2545 XXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYC 2724
+ Y + + + + + +E K+A + V +IRTV SL R+E FH Y
Sbjct: 871 LAFTPFILIAFYMQRTLMAKENMGSAKTMENCTKLAVEVVSNIRTVASLGREEMFHQNYI 930
Query: 2725 EYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAI 2904
L + ++ H G V+ ++SL+FF YAA Y G+ V + + DV++V A+
Sbjct: 931 GMLIPAVEISKRNTHFRGLVYGLARSLMFFAYAACMYYGTWCVIHRGILFGDVFKVSQAL 990
Query: 2905 SFCGQMIGNTTSFIPDVVKARLAASLLF-YLIEHPTPIDSLSDSGIVKPITGNISIRNVF 3081
I N +F P++ K AA +F +L P+ +D S G + V
Sbjct: 991 IMGTASIANALAFAPNMQKGVSAAKTIFTFLRRQPSIVDRPGVSRDPWHSEGYVRFDKVK 1050
Query: 3082 FNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNI 3261
F+YPTR + +VL+G L + G+ +ALVG SGCGKST + L++RFY+ D+G +ID ++
Sbjct: 1051 FSYPTRSEIQVLKGLELAVSKGQKIALVGPSGCGKSTCIQLIQRFYDVDEGATLIDECDV 1110
Query: 3262 RNLNISSLREQVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGL 3438
RN+++++LR Q+ IVSQEP LFD TI ENI YG N RNVT QEI+ A K +NIH FI L
Sbjct: 1111 RNVSMTNLRNQLGIVSQEPILFDRTIRENISYGDNARNVTDQEIISACKKSNIHEFIANL 1170
Query: 3439 PDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAA 3618
P GYDT +GEKG QLSGGQKQRIAIARAL+R+P ++LLDEATSALD ESEK+VQ+ALDAA
Sbjct: 1171 PLGYDTRMGEKGAQLSGGQKQRIAIARALIRNPKIMLLDEATSALDAESEKVVQDALDAA 1230
Query: 3619 KQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
+GRT + IAHRLST+ +SDVI + G + E G H +L+ +Y + Q
Sbjct: 1231 SEGRTTISIAHRLSTVVHSDVIFVFENGLVCEAGDHKQLLANRGLYYTLYKLQ 1283
>gi|19032275|dbj|BAB85651.1| multidrug resistance protein 1 homolog
[Triticum aestivum]
Length = 1262
Score = 812 bits (2098), Expect = 0.0
Identities = 476/1259 (37%), Positives = 725/1259 (56%), Gaps = 33/1259 (2%)
Frame = +1
Query: 94 KLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVD 273
K+ G+F Y +D+LL++ G++ AV +G PL++++ G + F + S +
Sbjct: 27 KVPLLGMFRYADRLDMLLMVVGSLGAVGNGVSEPLISVLFGDVINSFGESTTSTVL---- 82
Query: 274 NVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYL 453
V K + ++ LG+ S++Q+AC+ ER ++R YL
Sbjct: 83 ----------------RAVTKVVLNFIYLGIGTAVASFLQVACWTMAGERQSARIRSLYL 126
Query: 454 KAILRQQIQWFDKQQT-GNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYS 630
K++LRQ I +FD + T G +R++ D +++ LG+K LVQ+ +AF G+ + F
Sbjct: 127 KSVLRQDIAFFDTEMTTGEAVSRMSSDTVIIQDALGEKAGKLVQLTSAFFGGFIIAFTKG 186
Query: 631 WSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQET-YAVAGAIAEETFSSIRTVHSLNGH 807
W +TLVM+ PL+ ++GA +S M TR ++ T Y+ A E+T SIRTV S NG
Sbjct: 187 WLLTLVMLTSLPLVAIAGA-VSAQMLTRVSSKRLTSYSDAANTVEQTIGSIRTVVSFNGE 245
Query: 808 KRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRG 987
K+ ++ + ++ +T + + G G+G ++SSY LAFWYG LII D + G
Sbjct: 246 KKAIEMYNKFIKSAYRTVVEEGLVNGFGMGSVFCILFSSYGLAFWYGGKLII-DKGYTGG 304
Query: 988 LIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMK 1167
I TV FAVL+G+TSLG A P +++ + AA + I P+ID G++++N+K
Sbjct: 305 KIVTVLFAVLNGATSLGNATPSISAIAEGQSAAYRLFETIERKPEIDSDDTSGMIMENIK 364
Query: 1168 GDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKG 1347
G + KDV+FRYP+R +L G+SL++ +G +A+VG SG GKST+++L++RFYDP G
Sbjct: 365 GYVELKDVYFRYPARLGQLILDGLSLQVASGTTMAIVGESGSGKSTVISLVERFYDPQAG 424
Query: 1348 RVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANA 1527
VLIDGV+++ +N+ +R +IG+VSQEP+LF +I +NI G E AT +++ A ++ANA
Sbjct: 425 EVLIDGVNIKNLNLDWIRGKIGLVSQEPLLFMTSIKDNIIYGKEDATLEEIKRAAELANA 484
Query: 1528 NDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREV 1707
+FI +LP+GY T VG++G LSGGQKQRIAIARA++K+PKILLLDEATSALD E+ER V
Sbjct: 485 ANFIDKLPNGYDTLVGQRGTLLSGGQKQRIAIARAILKDPKILLLDEATSALDVESERIV 544
Query: 1708 QGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELM-SKQGIFYDMTXX 1884
Q AL++ RTT++VAHRLST+RNVD I V G IVE G+H L+ G + +
Sbjct: 545 QEALNRIMVERTTLVVAHRLSTVRNVDCITVVHQGKIVEQGTHHALVKDPNGAYSQLIRL 604
Query: 1885 XXXXXXXXEAGKD--IEDTISESAHSHLXXXXXXXXXXXXXXXIHQ----LAEEVEE--- 2037
+D + +++S+S + + L+ E+ E
Sbjct: 605 QETRGDERRKIQDSGVPNSLSKSTSLSIRRSMTKDSFGNSNRYSFKNPLGLSVELHEDEI 664
Query: 2038 ---------------CKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAE 2172
KAP + ++F N +V + + P+F ++ +
Sbjct: 665 TGEQNKDDLSNGKTLQKAP---IGRLFYLNKPEVPFLLLGAIAASVHGVIFPLFGILMSG 721
Query: 2173 IFNVYSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNL 2352
+ + P D+++ + FW + V++G F+ G G L ++R +F+N+
Sbjct: 722 VIKAFYEPPDKLRKDSSFWALISVVLGFASFIAIPAEYLLFGIAGGKLIERVRTLSFQNI 781
Query: 2353 LRQDIAFYDDLRHGTGKLCTRFATDAPNV-RYVFTRLPVVLASIVTICGALGIGFYYGWQ 2529
+ Q++A++D+ + +G L TR + DA NV R V L +++ S + I F W+
Sbjct: 782 VHQEVAWFDNPSNSSGALGTRLSVDALNVRRLVGDNLGLIVQSTAALITGFVIAFTADWR 841
Query: 2530 XXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQF 2709
GY +++ G ++ E+A +VA+ AV IRT+ S +++
Sbjct: 842 LALIITCVIPLVGAQGYAQVKFLKGFSEEAKEMYEDASQVATDAVGSIRTIASFCAEKRV 901
Query: 2710 HFTY---CEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPID 2880
TY CE LR+ ++ G F FS +++ YA FY+G+ FV Q D
Sbjct: 902 VTTYNKKCEALRK---QGIRSGIVGGLGFGFSFLVLYLTYALCFYVGAQFVRQGKTTFAD 958
Query: 2881 VYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIV-KPITG 3057
V++VFFA+ + ++ + KAR +A +F +++ + ID+ +D G+V + +TG
Sbjct: 959 VFKVFFALVLAAVGVSQASALASNATKARDSAISVFSILDRKSKIDTSNDEGLVLENVTG 1018
Query: 3058 NISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGM 3237
+I NV F YP+R D ++ FTL I + KT+ALVG SG GKSTI+ LLERFY+ D G+
Sbjct: 1019 DIHFSNVSFKYPSRPDVQIFSDFTLHIPSRKTIALVGESGSGKSTIIALLERFYDPDSGI 1078
Query: 3238 IMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANI 3417
I +DG I++L IS LR+Q+ +V QEP LF+ TI NI YG + VT +E+ AK AN
Sbjct: 1079 ISVDGVEIKSLRISWLRDQMGLVGQEPVLFNDTIRANITYGKHGEVTEEEVTAVAKAANA 1138
Query: 3418 HNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIV 3597
H FI LP GYDT VGEKG QLSGGQKQR+AIARA+++ P +LLLDEATSALD ESE+IV
Sbjct: 1139 HEFISSLPQGYDTLVGEKGVQLSGGQKQRVAIARAIIKDPKILLLDEATSALDAESERIV 1198
Query: 3598 QEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIR-KSEIYQKFCE 3771
Q+ALD RT +V+AHRLSTI+ +D+IA++ EGKI EKG H+ L+ K +Y E
Sbjct: 1199 QDALDRVMVSRTTIVVAHRLSTIKGADMIAVLKEGKIAEKGKHEALMGIKDGVYASLVE 1257
Score = 395 bits (1015), Expect = e-108
Identities = 227/597 (38%), Positives = 330/597 (55%), Gaps = 4/597 (0%)
Frame = +1
Query: 88 TVKLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVG 267
T++ G +Y ++ L+ G +AA +HG FPL I++ G+ F
Sbjct: 678 TLQKAPIGRLFYLNKPEVPFLLLGAIAASVHGVIFPLFGILMSGVIKAFYEPP------- 730
Query: 268 VDNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQN 447
D+ + + + +VLG F + F +L+ ++R
Sbjct: 731 --------------DKLRKDSSFWALISVVLGFASFIAIPAEYLLFGIAGGKLIERVRTL 776
Query: 448 YLKAILRQQIQWFDK--QQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGF 621
+ I+ Q++ WFD +G L RL+ D VR +GD L+VQ AA + G+ + F
Sbjct: 777 SFQNIVHQEVAWFDNPSNSSGALGTRLSVDALNVRRLVGDNLGLIVQSTAALITGFVIAF 836
Query: 622 FYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLN 801
W + L++ PL+ G K + + +E Y A +A + SIRT+ S
Sbjct: 837 TADWRLALIITCVIPLVGAQGYAQVKFLKGFSEEAKEMYEDASQVATDAVGSIRTIASFC 896
Query: 802 GHKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFD 981
KR + + E R+ GI G+G GFS L +Y +YAL F+ G+ + T
Sbjct: 897 AEKRVVTTYNKKCEALRKQGIRSGIVGGLGFGFSFLVLYLTYALCFYVGAQFVRQGKTTF 956
Query: 982 RGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDN 1161
+F VFFA++ + + A ++ AR +A +V +++ KID + EG++++N
Sbjct: 957 AD-VFKVFFALVLAAVGVSQASALASNATKARDSAISVFSILDRKSKIDTSNDEGLVLEN 1015
Query: 1162 MKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPT 1341
+ GDI F +V F+YPSR D+ + +L + + IALVG SG GKSTI+ LL+RFYDP
Sbjct: 1016 VTGDIHFSNVSFKYPSRPDVQIFSDFTLHIPSRKTIALVGESGSGKSTIIALLERFYDPD 1075
Query: 1342 KGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNE-HATHDQVVEACKM 1518
G + +DGV+++ + + LR+Q+G+V QEPVLF+ TI NI G T ++V K
Sbjct: 1076 SGIISVDGVEIKSLRISWLRDQMGLVGQEPVLFNDTIRANITYGKHGEVTEEEVTAVAKA 1135
Query: 1519 ANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAE 1698
ANA++FI LP GY T VGEKGVQLSGGQKQR+AIARA++K+PKILLLDEATSALD E+E
Sbjct: 1136 ANAHEFISSLPQGYDTLVGEKGVQLSGGQKQRVAIARAIIKDPKILLLDEATSALDAESE 1195
Query: 1699 REVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMS-KQGIF 1866
R VQ ALD+ RTTI+VAHRLSTI+ D I V K G I E G HE LM K G++
Sbjct: 1196 RIVQDALDRVMVSRTTIVVAHRLSTIKGADMIAVLKEGKIAEKGKHEALMGIKDGVY 1252
>gi|34894326|ref|NP_908488.1| unnamed protein product [Oryza sativa
(japonica cultivar-group)]
gi|8468012|dbj|BAA96612.1| unnamed protein product [Oryza sativa
(japonica cultivar-group)]
gi|27368863|emb|CAD59589.1| MDR-like ABC transporter [Oryza sativa
(japonica cultivar-group)]
Length = 1285
Score = 811 bits (2094), Expect = 0.0
Identities = 457/1230 (37%), Positives = 689/1230 (55%), Gaps = 21/1230 (1%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F + D L+ GT+ AV +GA P + ++ G + F A VV
Sbjct: 59 LFAFADKTDAALMALGTLGAVANGAALPFMTVLFGNLIDAFGGAMGIHDVV--------- 109
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
+ V + ++ L + S+VQ+ C+ ER ++R YLK ILRQ
Sbjct: 110 ----------NRVSMVSLEFIYLAIASAVASFVQVTCWMITGERQAARIRNLYLKTILRQ 159
Query: 472 QIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLV 648
+I +FDK TG + R++ D +++ +G+K +Q+ FL G+ V F W +TLV
Sbjct: 160 EIAFFDKYTNTGEVVGRMSGDTVLIQDAMGEKVGKFIQLVVTFLGGFIVAFAQGWLLTLV 219
Query: 649 MMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRF 828
MM P +V++GA MS +A + Q YA + + E+T SIRTV S G K+ ++++
Sbjct: 220 MMATIPPLVVAGAVMSNVVAKMASLGQAAYAESSVVVEQTIGSIRTVASFTGEKQAVEKY 279
Query: 829 YNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFF 1008
+L+ ++G+ + G+G+G + ++ Y+L WYG+ LI+ + + V F
Sbjct: 280 NKSLKSAYKSGVREGLAAGLGMGTVMVLLFCGYSLGIWYGAKLILLKG-YTGAKVMNVIF 338
Query: 1009 AVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKD 1188
AVL+GS +LG A P + +F + AA + IN P+ID YS G+ D+++GDI F+D
Sbjct: 339 AVLTGSLALGQASPSMKAFAGGQAAAYKMFETINRKPEIDAYSTTGMKPDDIRGDIEFRD 398
Query: 1189 VHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGV 1368
V+F YP+R D + +G SL + +G +ALVG SG GKST+++L++RFYDP G VLIDGV
Sbjct: 399 VYFSYPTRPDEQIFRGFSLSIPSGTTVALVGQSGSGKSTVISLIERFYDPQLGDVLIDGV 458
Query: 1369 DLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRL 1548
+L+E + +R +IG+VSQEPVLF +I ENI G ++AT ++ A ++ANA+ FI ++
Sbjct: 459 NLKEFQLRWIRSKIGLVSQEPVLFAASIKENIAYGKDNATDQEIRAAAELANASKFIDKM 518
Query: 1549 PDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQA 1728
P G T VGE G QLSGGQKQRIAIARA++K+P+ILLLDEATSALD E+ER VQ ALD+
Sbjct: 519 PQGLDTSVGEHGTQLSGGQKQRIAIARAILKDPRILLLDEATSALDAESERIVQEALDRV 578
Query: 1729 QAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELM-SKQGIFYDM---------T 1878
RTT+IVAHRLST+RN D I V G +VE G H EL+ +G + +
Sbjct: 579 MTNRTTVIVAHRLSTVRNADTIAVIHQGTLVEKGPHHELLKDPEGAYSQLIKLQEANRQD 638
Query: 1879 XXXXXXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEE------C 2040
+GK + +I++SA L ++++ C
Sbjct: 639 KSDRKGDSGARSGKQL--SINQSASRSRRSSRDNSHHSFSVPFGMPLGIDIQDGSSDNLC 696
Query: 2041 KAPP--TSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQA 2214
P + ++ N ++ + P+FA++ + + + P ++
Sbjct: 697 DGMPQDVPLSRLASLNKPEIPVLILGSIASVISGVIFPIFAILLSNVIKAFYEPPHLLRK 756
Query: 2215 NVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHG 2394
+ FW MF++ G +F+ S+ G L ++R F+ ++ +I ++D +
Sbjct: 757 DSQFWSSMFLVFGAVYFLSLPVSSYLFSIAGCRLIKRIRLMTFEKVVNMEIEWFDHPENS 816
Query: 2395 TGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXM 2571
+G + R + DA VR V L +V+ + T+ L I F W+ +
Sbjct: 817 SGAIGARLSADAAKVRGLVGDALQLVVQNTTTLIAGLVIAFVSNWELSLIILALIPLIGL 876
Query: 2572 GGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNT 2751
G+ +M+ G + EEA +VA+ AV IRTV S + +E+ Y + P T
Sbjct: 877 NGWIQMKFIQGFSADAKMMYEEASQVANDAVSSIRTVVSFSAEEKVMDLYKKKCEGPLRT 936
Query: 2752 NLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGN 2931
++ G F S L+F +YAA+FY G+ V + V+RVF A++ +
Sbjct: 937 GIRTGIISGIGFGVSFFLLFGVYAASFYAGARLVEENKTTFPKVFRVFLALAMAAIGVSQ 996
Query: 2932 TTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGI-VKPITGNISIRNVFFNYPTRKDT 3108
+++ D KA+ A S +F +++ + ID D+G+ V+ + GNI ++V F YPTR D
Sbjct: 997 SSTLTSDSSKAKSAVSSIFAIVDRKSRIDPSEDAGVTVETLHGNIEFQHVSFRYPTRPDV 1056
Query: 3109 KVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLR 3288
++ + L I +GKTVALVG SG GKST + LL+RFY+ D G I++DG +I+ + LR
Sbjct: 1057 EIFRDLCLTIHSGKTVALVGESGSGKSTAISLLQRFYDPDVGHILLDGVDIQKFQLKWLR 1116
Query: 3289 EQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGE 3468
+Q+ +VSQEP LF+ T+ NI YG T EI+EAAK+AN H FI GY T VGE
Sbjct: 1117 QQMGLVSQEPALFNDTVRANIAYGKEGEATESEIIEAAKLANAHKFISSSHQGYGTTVGE 1176
Query: 3469 KGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIA 3648
+G QLSGGQKQRIAIARA+V+ P +LLLDEATSALD ESE++VQ+ALD RT +++A
Sbjct: 1177 RGAQLSGGQKQRIAIARAIVKDPKILLLDEATSALDAESERVVQDALDRVMVNRTTVIVA 1236
Query: 3649 HRLSTIQNSDVIAIVSEGKIVEKGTHDELI 3738
HRLSTIQN+D+IA+V G I+EKG HD L+
Sbjct: 1237 HRLSTIQNADLIAVVKNGVIIEKGKHDTLM 1266
Score = 391 bits (1005), Expect = e-107
Identities = 227/582 (39%), Positives = 339/582 (58%), Gaps = 5/582 (0%)
Frame = +1
Query: 136 DLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDE 315
++ +LI G++A+VI G FP+ AI+L + F P L
Sbjct: 715 EIPVLILGSIASVISGVIFPIFAILLSNVIKAFYE-------------------PPHLLR 755
Query: 316 FNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD-- 489
+S+ + +LV G + F + V F RL+ ++R + ++ +I+WFD
Sbjct: 756 KDSQF--WSSMFLVFGAVYFLSLPVSSYLFSIAGCRLIKRIRLMTFEKVVNMEIEWFDHP 813
Query: 490 KQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPL 669
+ +G + ARL+ D +VR +GD L+VQ +AG + F +W ++L+++ PL
Sbjct: 814 ENSSGAIGARLSADAAKVRGLVGDALQLVVQNTTTLIAGLVIAFVSNWELSLIILALIPL 873
Query: 670 IVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVG 849
I L+G K + + + Y A +A + SSIRTV S + ++ +D + E
Sbjct: 874 IGLNGWIQMKFIQGFSADAKMMYEEASQVANDAVSSIRTVVSFSAEEKVMDLYKKKCEGP 933
Query: 850 RQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLII-NDPTFDRGLIFTVFFAVLSGS 1026
+TGI GIG G S ++ YA +F+ G+ L+ N TF + +F VF A+ +
Sbjct: 934 LRTGIRTGIISGIGFGVSFFLLFGVYAASFYAGARLVEENKTTFPK--VFRVFLALAMAA 991
Query: 1027 TSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYP 1206
+ + + A+ A S++ +++ +IDP G+ V+ + G+I F+ V FRYP
Sbjct: 992 IGVSQSSTLTSDSSKAKSAVSSIFAIVDRKSRIDPSEDAGVTVETLHGNIEFQHVSFRYP 1051
Query: 1207 SRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVN 1386
+R D+ + + + L + +G +ALVG SG GKST ++LLQRFYDP G +L+DGVD+++
Sbjct: 1052 TRPDVEIFRDLCLTIHSGKTVALVGESGSGKSTAISLLQRFYDPDVGHILLDGVDIQKFQ 1111
Query: 1387 VHSLREQIGIVSQEPVLFDGTIYENIKMGNE-HATHDQVVEACKMANANDFIKRLPDGYG 1563
+ LR+Q+G+VSQEP LF+ T+ NI G E AT +++EA K+ANA+ FI GYG
Sbjct: 1112 LKWLRQQMGLVSQEPALFNDTVRANIAYGKEGEATESEIIEAAKLANAHKFISSSHQGYG 1171
Query: 1564 TRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRT 1743
T VGE+G QLSGGQKQRIAIARA+VK+PKILLLDEATSALD E+ER VQ ALD+ RT
Sbjct: 1172 TTVGERGAQLSGGQKQRIAIARAIVKDPKILLLDEATSALDAESERVVQDALDRVMVNRT 1231
Query: 1744 TIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMS-KQGIF 1866
T+IVAHRLSTI+N D I V K G I+E G H+ LM+ K G +
Sbjct: 1232 TVIVAHRLSTIQNADLIAVVKNGVIIEKGKHDTLMNIKDGAY 1273
Score = 315 bits (807), Expect = 5e-84
Identities = 188/507 (37%), Positives = 277/507 (54%), Gaps = 3/507 (0%)
Frame = +1
Query: 2239 FVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRF 2418
F+ + I V F C GE ++R K +LRQ+IAF+D + TG++ R
Sbjct: 119 FIYLAIASAVASFVQVTCWMITGERQAARIRNLYLKTILRQEIAFFDKYTN-TGEVVGRM 177
Query: 2419 ATDAPNVRYVF-TRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQM 2595
+ D ++ ++ + +VT G + F GW + G +
Sbjct: 178 SGDTVLIQDAMGEKVGKFIQLVVTFLGGFIVAFAQGWLLTLVMMATIPPLVVAGAVMSNV 237
Query: 2596 RFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTY 2775
E+ V Q + IRTV S ++Q Y + L+ + + ++
Sbjct: 238 VAKMASLGQAAYAESSVVVEQTIGSIRTVASFTGEKQAVEKYNKSLKSAYKSGVREGLAA 297
Query: 2776 GAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDV 2955
G L+F Y+ + G+ + + V V FA+ +G + +
Sbjct: 298 GLGMGTVMVLLFCGYSLGIWYGAKLILLKGYTGAKVMNVIFAVLTGSLALGQASPSMKAF 357
Query: 2956 VKARLAASLLFYLIEHPTPIDSLSDSGIVKP--ITGNISIRNVFFNYPTRKDTKVLQGFT 3129
+ AA +F I ID+ S +G+ KP I G+I R+V+F+YPTR D ++ +GF+
Sbjct: 358 AGGQAAAYKMFETINRKPEIDAYSTTGM-KPDDIRGDIEFRDVYFSYPTRPDEQIFRGFS 416
Query: 3130 LDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVS 3309
L I +G TVALVG SG GKST++ L+ERFY+ G ++IDG N++ + +R ++ +VS
Sbjct: 417 LSIPSGTTVALVGQSGSGKSTVISLIERFYDPQLGDVLIDGVNLKEFQLRWIRSKIGLVS 476
Query: 3310 QEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSG 3489
QEP LF +I ENI YG + N T QEI AA++AN FI +P G DT VGE GTQLSG
Sbjct: 477 QEPVLFAASIKENIAYGKD-NATDQEIRAAAELANASKFIDKMPQGLDTSVGEHGTQLSG 535
Query: 3490 GQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQ 3669
GQKQRIAIARA+++ P +LLLDEATSALD ESE+IVQEALD RT +++AHRLST++
Sbjct: 536 GQKQRIAIARAILKDPRILLLDEATSALDAESERIVQEALDRVMTNRTTVIVAHRLSTVR 595
Query: 3670 NSDVIAIVSEGKIVEKGTHDELIRKSE 3750
N+D IA++ +G +VEKG H EL++ E
Sbjct: 596 NADTIAVIHQGTLVEKGPHHELLKDPE 622
>gi|27368855|emb|CAD59585.1| MDR-like ABC transporter [Oryza sativa
(japonica cultivar-group)]
Length = 1267
Score = 810 bits (2093), Expect = 0.0
Identities = 469/1246 (37%), Positives = 708/1246 (56%), Gaps = 30/1246 (2%)
Frame = +1
Query: 94 KLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVD 273
KL G+F Y GVD L+ GTVAA+ +G PL+ +V + F G D
Sbjct: 29 KLPFLGMFRYADGVDKALMAVGTVAAMANGMSEPLMTVVFSAVIDCF----------GGD 78
Query: 274 NVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYL 453
+V+ V K +YY+ LGV S++Q++C+ ER ++R YL
Sbjct: 79 DVST----------VLHRVSKVVLYYIYLGVGTSMASFLQVSCWTMAGERQSARIRSLYL 128
Query: 454 KAILRQQIQWFDKQQT-GNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYS 630
+AIL Q I +FD + T G +R++ D +++ LG+K +Q+ AF+ G+ +GF
Sbjct: 129 EAILTQDIAFFDVEMTTGEAASRISADTVLIQDALGEKVGKYIQVLTAFVGGFVIGFIRG 188
Query: 631 WSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHK 810
W + LV+M P + S A +S+ A + +Y+ AG + E+T SIR V S NG K
Sbjct: 189 WMLALVVMACIPPSIFSFALVSRLRAQISGKTHVSYSYAGNVVEQTIGSIRMVVSFNGEK 248
Query: 811 RELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGL 990
R + + ++ + I++ G G+G +Y SY+LAFWYG+ L+I+ + G
Sbjct: 249 RAITMYNTLIKKAYKATIMEGIISGFGIGSIFFVVYCSYSLAFWYGAKLVISKG-YTGGQ 307
Query: 991 IFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKG 1170
+ V FA+L+GS ++G A P +++ + AA + +IN P ID GI+++++KG
Sbjct: 308 VINVVFAILTGSMAIGNASPSISAIAEGQSAAHRLFEIINRKPNIDITGTSGIILEDIKG 367
Query: 1171 DISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGR 1350
++ KDV F YP+R + +L G+ L++ G +A+VG SG GKSTI++L++RFYDP G
Sbjct: 368 NVELKDVCFSYPARPEQLILDGLCLQVPNGTTMAIVGQSGSGKSTIISLVERFYDPQDGE 427
Query: 1351 VLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAN 1530
VLIDG++++ + +H +R ++ +VSQEP+LF +I +NI G E+AT +++ A ++ANA
Sbjct: 428 VLIDGINIKTLKLHWIRGKMSLVSQEPLLFMTSIKDNITYGKENATDEEIKRAAELANAA 487
Query: 1531 DFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQ 1710
+FI +LP+ Y T VG+ G QLSGGQKQRIAIARA++KNPK+LLLDEATSALD E+ER VQ
Sbjct: 488 NFIDKLPNAYDTMVGQHGAQLSGGQKQRIAIARAILKNPKVLLLDEATSALDVESERLVQ 547
Query: 1711 GALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFY------- 1869
AL++ GRTT+IVAHRLSTI+N D I V G IV+ GSH+EL+ Y
Sbjct: 548 EALNRVMIGRTTLIVAHRLSTIKNADCIAVVHQGKIVDQGSHDELIKDPDGAYSQLIQLQ 607
Query: 1870 --------DMTXXXXXXXXXXEAGKDIEDT-ISESAHSHLXXXXXXXXXXXXXXXIHQ-- 2016
D+ +E + I++S + +H+
Sbjct: 608 QTHTEEMHDVQYSEVSTSRLKSRSLSLEQSMINDSPRNRRKNSLAKHIGSSGSDGLHKHG 667
Query: 2017 LAEEVE--EC-------KAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYA 2169
L +E E EC KAP + ++F N + + P+F+++ +
Sbjct: 668 LTDEPEDKECGDNKDINKAP---IRRLFNLNKPEAPILLLAIITAFVHGLLFPIFSIMMS 724
Query: 2170 EIFNVYSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKN 2349
+ P Q++ + FW M +LM I V G G L ++R +F++
Sbjct: 725 GGIRTFYYPPHQLRKDSRFWALMCILMAIISLVSIQLEYFLFGMAGGKLIERVRCLSFQS 784
Query: 2350 LLRQDIAFYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGW 2526
++ Q+++++DD H +G L + DA N+R V L +++ IVT+ I F W
Sbjct: 785 IVHQEVSWFDDPSHSSGSLGAKLYIDALNIRRLVGDNLAILVQCIVTLIAGFTIAFASDW 844
Query: 2527 QXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQ 2706
+ + Y +++ G + E+A +V ++A+ IRTV S +++
Sbjct: 845 KLTLTIMCPIPLVGLQNYVQLKFLKGFSEDAKVMYEDASQVVTEAIGSIRTVASFCAEKR 904
Query: 2707 FHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVY 2886
TY + + +++ G F+FS +++ YA FY+G+ FV+ DV+
Sbjct: 905 VIKTYNQKCQASMKESIRSGMVGGLGFSFSYLMVYLTYALCFYVGAQFVHGGKSTFKDVF 964
Query: 2887 RVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIV-KPITGNI 3063
RV+FA+ F I T++ D KA +A+ + +I+ + IDS D GI+ + + G I
Sbjct: 965 RVYFALVFTAFGISQTSAMASDSSKAHESAASILAIIDRKSNIDSSIDEGIILEKVNGTI 1024
Query: 3064 SIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIM 3243
+ +V F YP+R D +VL FTL I +GKTVALVG SG GKST++ LLERFY+ G I
Sbjct: 1025 ELNHVNFKYPSRPDVQVLCDFTLGIPSGKTVALVGESGSGKSTVIALLERFYDPHSGTIS 1084
Query: 3244 IDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHN 3423
+D ++NL +S LR+Q+ +VSQEP LF+ TI NI YG VT +EI+ AK +N H
Sbjct: 1085 LDRVELKNLKLSWLRDQMGLVSQEPILFNDTIHANIAYGRKGQVTEEEIIAVAKASNAHE 1144
Query: 3424 FILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQE 3603
FI LP GY+T VGE+GTQLSGGQKQRIAIARA+++ P +LLLDEATSALD ESE+IVQ+
Sbjct: 1145 FISSLPQGYNTTVGERGTQLSGGQKQRIAIARAILKDPKILLLDEATSALDAESERIVQD 1204
Query: 3604 ALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIR 3741
ALD RT +V+AHRLSTI+ +DVIA++ +G I EKG HD L+R
Sbjct: 1205 ALDQVMVSRTTIVVAHRLSTIKGADVIAVIKDGSIAEKGQHDSLMR 1250
Score = 363 bits (933), Expect = 1e-98
Identities = 205/578 (35%), Positives = 319/578 (54%), Gaps = 3/578 (0%)
Frame = +1
Query: 145 LLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNS 324
+L+ + A +HG FP+ +I++ G F + +
Sbjct: 701 ILLLAIITAFVHGLLFPIFSIMMSGGIRTFYYPPH---------------------QLRK 739
Query: 325 EVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD--KQQ 498
+ + + +++ ++ + ++ F +L+ ++R ++I+ Q++ WFD
Sbjct: 740 DSRFWALMCILMAIISLVSIQLEYFLFGMAGGKLIERVRCLSFQSIVHQEVSWFDDPSHS 799
Query: 499 TGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVL 678
+G+L A+L D +R +GD A+LVQ +AG+ + F W +TL +M PL+ L
Sbjct: 800 SGSLGAKLYIDALNIRRLVGDNLAILVQCIVTLIAGFTIAFASDWKLTLTIMCPIPLVGL 859
Query: 679 SGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQT 858
K + + + Y A + E SIRTV S KR + + + +
Sbjct: 860 QNYVQLKFLKGFSEDAKVMYEDASQVVTEAIGSIRTVASFCAEKRVIKTYNQKCQASMKE 919
Query: 859 GIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLG 1038
I G+G FS L +Y +YAL F+ G+ + + + +F V+FA++ + +
Sbjct: 920 SIRSGMVGGLGFSFSYLMVYLTYALCFYVGAQFVHGGKSTFKD-VFRVYFALVFTAFGIS 978
Query: 1039 GALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKD 1218
+ A +A+++L +I+ ID EGI+++ + G I V+F+YPSR D
Sbjct: 979 QTSAMASDSSKAHESAASILAIIDRKSNIDSSIDEGIILEKVNGTIELNHVNFKYPSRPD 1038
Query: 1219 IHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSL 1398
+ VL +L + +G +ALVG SG GKST++ LL+RFYDP G + +D V+L+ + + L
Sbjct: 1039 VQVLCDFTLGIPSGKTVALVGESGSGKSTVIALLERFYDPHSGTISLDRVELKNLKLSWL 1098
Query: 1399 REQIGIVSQEPVLFDGTIYENIKMGNE-HATHDQVVEACKMANANDFIKRLPDGYGTRVG 1575
R+Q+G+VSQEP+LF+ TI+ NI G + T ++++ K +NA++FI LP GY T VG
Sbjct: 1099 RDQMGLVSQEPILFNDTIHANIAYGRKGQVTEEEIIAVAKASNAHEFISSLPQGYNTTVG 1158
Query: 1576 EKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIV 1755
E+G QLSGGQKQRIAIARA++K+PKILLLDEATSALD E+ER VQ ALDQ RTTI+V
Sbjct: 1159 ERGTQLSGGQKQRIAIARAILKDPKILLLDEATSALDAESERIVQDALDQVMVSRTTIVV 1218
Query: 1756 AHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFY 1869
AHRLSTI+ D I V K G+I E G H+ LM G Y
Sbjct: 1219 AHRLSTIKGADVIAVIKDGSIAEKGQHDSLMRINGGVY 1256
>gi|15217785|ref|NP_171753.1| multidrug resistance P-glycoprotein,
putative [Arabidopsis thaliana]
gi|25297455|pir||E86155 probable ABC transporter [imported] -
Arabidopsis thaliana
gi|9972378|gb|AAG10628.1| Putative ABC transporter [Arabidopsis
thaliana]
Length = 1278
Score = 810 bits (2092), Expect = 0.0
Identities = 458/1243 (36%), Positives = 697/1243 (55%), Gaps = 31/1243 (2%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNP 285
Y +F + D+LL+I G++ A+ +G P + ++ G + F + QN+ +V V
Sbjct: 44 YKLFAFADSSDVLLMICGSIGAIGNGMSLPFMTLLFGDLIDSFGKNQNNKDIVDV----- 98
Query: 286 EGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAIL 465
V K C+ ++ LG+ +++Q+AC+ ER ++R YLK IL
Sbjct: 99 --------------VSKVCLKFVYLGLGTLGAAFLQVACWMITGERQAARIRSTYLKTIL 144
Query: 466 RQQIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMT 642
RQ I +FD + TG + R++ D +++ +G+K +Q+ + F+ G+ + F W +T
Sbjct: 145 RQDIGFFDVETNTGEVVGRMSGDTVLIQDAMGEKVGKFIQLVSTFVGGFVLAFIKGWLLT 204
Query: 643 LVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELD 822
LVM+ PL+ ++GA M+ + + Q YA A + E+T SIRTV S G K+ ++
Sbjct: 205 LVMLTSIPLLAMAGAAMALIVTRASSRGQAAYAKAATVVEQTIGSIRTVASFTGEKQAIN 264
Query: 823 RFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTV 1002
+ + ++ I + G+G+G +SSYALA W+G +I+ + + G + V
Sbjct: 265 SYKKFITSAYKSSIQQGFSTGLGLGVMFFVFFSSYALAIWFGGKMIL-EKGYTGGAVINV 323
Query: 1003 FFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISF 1182
V++GS SLG P + +F + AA + I P ID Y + G ++++++GDI
Sbjct: 324 IIIVVAGSMSLGQTSPCVTAFAAGQAAAYKMFETIKRKPLIDAYDVNGKVLEDIRGDIEL 383
Query: 1183 KDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLID 1362
KDVHF YP+R D + G SL + +G ALVG SG GKST+++L++RFYDP G VLID
Sbjct: 384 KDVHFSYPARPDEEIFDGFSLFIPSGATAALVGESGSGKSTVISLIERFYDPKSGAVLID 443
Query: 1363 GVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIK 1542
GV+L+E + +R +IG+VSQEPVLF +I ENI G E+AT +++ A ++ANA FI
Sbjct: 444 GVNLKEFQLKWIRSKIGLVSQEPVLFSSSIMENIAYGKENATVEEIKAATELANAAKFID 503
Query: 1543 RLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALD 1722
+LP G T VGE G QLSGGQKQRIAIARA++K+P+ILLLDEATSALD E+ER VQ ALD
Sbjct: 504 KLPQGLDTMVGEHGTQLSGGQKQRIAIARAILKDPRILLLDEATSALDAESERVVQEALD 563
Query: 1723 QAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXX 1902
+ RTT+IVAHRLST+RN D I V G +VE GSH EL+ D
Sbjct: 564 RVMVNRTTVIVAHRLSTVRNADMIAVIHRGKMVEKGSHSELLK------DSEGAYSQLIR 617
Query: 1903 XXEAGKDIEDTISESA----HSHLXXXXXXXXXXXXXXXIHQL----------------- 2019
E KD++ + S +S+L H L
Sbjct: 618 LQEINKDVKTSELSSGSSFRNSNLKKSMEGTSSVGNSSRHHSLNVLGLTTGLDLGSHSQR 677
Query: 2020 AEEVEECKA-----PPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNV 2184
A + E A P S+ +I N ++ ++ P+F ++ + +
Sbjct: 678 AGQDETGTASQEPLPKVSLTRIAALNKPEIPVLLLGTVAAAINGAIFPLFGILISRVIEA 737
Query: 2185 YSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQD 2364
+ PA +++ + FW +FV +G+T + T G L ++R F+ + +
Sbjct: 738 FFKPAHELKRDSRFWAIIFVALGVTSLIVSPTQMYLFAVAGGKLIRRIRSMCFEKAVHME 797
Query: 2365 IAFYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXX 2541
+A++D+ ++ +G + R + DA +R V L + + ++ + L I F W+
Sbjct: 798 VAWFDEPQNSSGTMGARLSADATLIRALVGDALSLAVQNVASAASGLIIAFTASWELALI 857
Query: 2542 XXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTY 2721
+ G+ +++ G EEA +VA+ AV IRTV S +E+ Y
Sbjct: 858 ILVMLPLIGINGFVQVKFMKGFSADAKSKYEEASQVANDAVGSIRTVASFCAEEKVMQMY 917
Query: 2722 CEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFA 2901
+ P +K G F FS ++F +YA +FY G+ V +V++VFFA
Sbjct: 918 KKQCEGPIKDGIKQGFISGLGFGFSFFILFCVYATSFYAGARLVEDGKTTFNNVFQVFFA 977
Query: 2902 ISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNV 3078
++ I +++F PD KA++AA+ +F +I+ + IDS ++G +++ + G+I +R++
Sbjct: 978 LTMAAIGISQSSTFAPDSSKAKVAAASIFAIIDRKSKIDSSDETGTVLENVKGDIELRHL 1037
Query: 3079 FFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDN 3258
F YP R D ++ + L I+AGKTVALVG SG GKST++ LL+RFY+ D G I +DG
Sbjct: 1038 SFTYPARPDIQIFRDLCLTIRAGKTVALVGESGSGKSTVISLLQRFYDPDSGHITLDGVE 1097
Query: 3259 IRNLNISSLREQVCIVSQEPTLFDCTIGENICYG--TNRNVTYQEIVEAAKMANIHNFIL 3432
++ L + LR+Q+ +V QEP LF+ TI NI YG + T EI+ AA++AN H FI
Sbjct: 1098 LKKLQLKWLRQQMGLVGQEPVLFNDTIRANIAYGKGSEEAATESEIIAAAELANAHKFIS 1157
Query: 3433 GLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALD 3612
+ GYDT VGE+G QLSGGQKQR+AIARA+V+ P +LLLDEATSALD ESE++VQ+ALD
Sbjct: 1158 SIQQGYDTVVGERGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERVVQDALD 1217
Query: 3613 AAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIR 3741
RT +V+AHRLSTI+N+DVIA+V G I EKGTH+ LI+
Sbjct: 1218 RVMVNRTTIVVAHRLSTIKNADVIAVVKNGVIAEKGTHETLIK 1260
Score = 387 bits (993), Expect = e-105
Identities = 220/583 (37%), Positives = 333/583 (56%), Gaps = 5/583 (0%)
Frame = +1
Query: 136 DLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDE 315
++ +L+ GTVAA I+GA FPL I++ + F + + E
Sbjct: 706 EIPVLLLGTVAAAINGAIFPLFGILISRVIEAFFKPAH---------------------E 744
Query: 316 FNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQ 495
+ + I ++ LGV S Q+ F +L+ ++R + + ++ WFD+
Sbjct: 745 LKRDSRFWAIIFVALGVTSLIVSPTQMYLFAVAGGKLIRRIRSMCFEKAVHMEVAWFDEP 804
Query: 496 Q--TGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPL 669
Q +G + ARL+ D +R +GD +L VQ A+ +G + F SW + L+++ PL
Sbjct: 805 QNSSGTMGARLSADATLIRALVGDALSLAVQNVASAASGLIIAFTASWELALIILVMLPL 864
Query: 670 IVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVG 849
I ++G K M + + Y A +A + SIRTV S ++ + + E
Sbjct: 865 IGINGFVQVKFMKGFSADAKSKYEEASQVANDAVGSIRTVASFCAEEKVMQMYKKQCEGP 924
Query: 850 RQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGST 1029
+ GI + G+G GFS ++ YA +F+ G+ L+ + T +F VFFA+ +
Sbjct: 925 IKDGIKQGFISGLGFGFSFFILFCVYATSFYAGARLVEDGKTTFNN-VFQVFFALTMAAI 983
Query: 1030 SLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPS 1209
+ + A+ AA+++ +I+ KID G +++N+KGDI + + F YP+
Sbjct: 984 GISQSSTFAPDSSKAKVAAASIFAIIDRKSKIDSSDETGTVLENVKGDIELRHLSFTYPA 1043
Query: 1210 RKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNV 1389
R DI + + + L ++AG +ALVG SG GKST+++LLQRFYDP G + +DGV+L+++ +
Sbjct: 1044 RPDIQIFRDLCLTIRAGKTVALVGESGSGKSTVISLLQRFYDPDSGHITLDGVELKKLQL 1103
Query: 1390 HSLREQIGIVSQEPVLFDGTIYENIKMGN---EHATHDQVVEACKMANANDFIKRLPDGY 1560
LR+Q+G+V QEPVLF+ TI NI G E AT +++ A ++ANA+ FI + GY
Sbjct: 1104 KWLRQQMGLVGQEPVLFNDTIRANIAYGKGSEEAATESEIIAAAELANAHKFISSIQQGY 1163
Query: 1561 GTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGR 1740
T VGE+G+QLSGGQKQR+AIARA+VK PKILLLDEATSALD E+ER VQ ALD+ R
Sbjct: 1164 DTVVGERGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERVVQDALDRVMVNR 1223
Query: 1741 TTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFY 1869
TTI+VAHRLSTI+N D I V K G I E G+HE L+ +G Y
Sbjct: 1224 TTIVVAHRLSTIKNADVIAVVKNGVIAEKGTHETLIKIEGGVY 1266
Score = 318 bits (814), Expect = 8e-85
Identities = 186/521 (35%), Positives = 281/521 (53%), Gaps = 3/521 (0%)
Frame = +1
Query: 2230 CGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLC 2409
C FV +G+ F C GE ++R K +LRQDI F+D + TG++
Sbjct: 103 CLKFVYLGLGTLGAAFLQVACWMITGERQAARIRSTYLKTILRQDIGFFD-VETNTGEVV 161
Query: 2410 TRFATDAPNVRYVF-TRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFE 2586
R + D ++ ++ + + T G + F GW M G
Sbjct: 162 GRMSGDTVLIQDAMGEKVGKFIQLVSTFVGGFVLAFIKGWLLTLVMLTSIPLLAMAGAAM 221
Query: 2587 MQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHA 2766
+ R +A V Q + IRTV S ++Q +Y +++ + ++++
Sbjct: 222 ALIVTRASSRGQAAYAKAATVVEQTIGSIRTVASFTGEKQAINSYKKFITSAYKSSIQQG 281
Query: 2767 HTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFI 2946
+ G + F YA A + G + ++ V V + +G T+ +
Sbjct: 282 FSTGLGLGVMFFVFFSSYALAIWFGGKMILEKGYTGGAVINVIIIVVAGSMSLGQTSPCV 341
Query: 2947 PDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTKVLQG 3123
+ AA +F I+ ID+ +G +++ I G+I +++V F+YP R D ++ G
Sbjct: 342 TAFAAGQAAAYKMFETIKRKPLIDAYDVNGKVLEDIRGDIELKDVHFSYPARPDEEIFDG 401
Query: 3124 FTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCI 3303
F+L I +G T ALVG SG GKST++ L+ERFY+ G ++IDG N++ + +R ++ +
Sbjct: 402 FSLFIPSGATAALVGESGSGKSTVISLIERFYDPKSGAVLIDGVNLKEFQLKWIRSKIGL 461
Query: 3304 VSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQL 3483
VSQEP LF +I ENI YG N T +EI A ++AN FI LP G DT VGE GTQL
Sbjct: 462 VSQEPVLFSSSIMENIAYG-KENATVEEIKAATELANAAKFIDKLPQGLDTMVGEHGTQL 520
Query: 3484 SGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLST 3663
SGGQKQRIAIARA+++ P +LLLDEATSALD ESE++VQEALD RT +++AHRLST
Sbjct: 521 SGGQKQRIAIARAILKDPRILLLDEATSALDAESERVVQEALDRVMVNRTTVIVAHRLST 580
Query: 3664 IQNSDVIAIVSEGKIVEKGTHDELIRKSE-IYQKFCETQRI 3783
++N+D+IA++ GK+VEKG+H EL++ SE Y + Q I
Sbjct: 581 VRNADMIAVIHRGKMVEKGSHSELLKDSEGAYSQLIRLQEI 621
>gi|34913530|ref|NP_918112.1| putative multidrug resistance protein
[Oryza sativa (japonica cultivar-group)]
gi|20146370|dbj|BAB89151.1| putative multidrug resistance protein
[Oryza sativa (japonica cultivar-group)]
gi|27368871|emb|CAD59593.1| MDR-like ABC transporter [Oryza sativa
(japonica cultivar-group)]
Length = 1287
Score = 808 bits (2087), Expect = 0.0
Identities = 466/1245 (37%), Positives = 686/1245 (54%), Gaps = 35/1245 (2%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F + G D L+ G AAV +G PL+ + G + F + D +
Sbjct: 47 MFAFADGADAALMAVGAAAAVANGMAQPLMTFIFGDVINAFGSTSSPDVL---------- 96
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
++V K + ++ LG+ F S +Q++C+ ER ++R YLKAILRQ
Sbjct: 97 ----------AKVTKVILNFVYLGIGAGFVSTLQVSCWTITGERQAARIRALYLKAILRQ 146
Query: 472 QIQWFDKQQ-TGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLV 648
I +FDK+ TG + R++ D +++ +G+K +Q+ + F G+ + F W + LV
Sbjct: 147 DIAFFDKEMSTGQVVERMSGDTFLIQDAIGEKSGKCIQLLSTFFGGFIIAFVRGWLLALV 206
Query: 649 MMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRF 828
++ P I ++GA +S+ M + QE Y AG IAE+T +IRTV S NG K+ ++ +
Sbjct: 207 LLSCIPPIAVAGAFVSRLMTRISTRMQEKYGDAGNIAEQTIGAIRTVASFNGEKQAINTY 266
Query: 829 YNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFF 1008
+ ++ + + G+G+G ++ SY LA WYGS LI+N ++ G++ V
Sbjct: 267 NKFIRKAYESTLQEGVVNGLGLGTVMAILFCSYGLAVWYGSKLIVNRG-YNGGIVINVLM 325
Query: 1009 AVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKD 1188
+V+ G+ SLG A P + +F +GAA + + I P ID +GI+++++ GD+ KD
Sbjct: 326 SVMMGAMSLGQATPSITAFAEGQGAAYRMFKTIKRQPDIDVCDTKGIILEDITGDVELKD 385
Query: 1189 VHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGV 1368
V+F YP+R + V G SL++ +G +ALVG SG GKST+++L++RFYDP G VLIDG+
Sbjct: 386 VYFSYPTRPEYLVFNGFSLQIPSGRTMALVGESGSGKSTVISLVERFYDPQSGEVLIDGI 445
Query: 1369 DLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRL 1548
D+R +N+ +R +I +VSQEPVLF TI ENI G E T +++ A ++ANA F+ +L
Sbjct: 446 DIRRMNLGWIRGKISLVSQEPVLFSSTIRENIAYGKEDQTLEEIKRAVELANAAKFVDKL 505
Query: 1549 PDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQA 1728
P+G T VGE+G+QLSGGQKQRIAIARA++KNP+ILLLDEATSALD E+ER VQ AL++
Sbjct: 506 PNGLETMVGERGIQLSGGQKQRIAIARAIIKNPRILLLDEATSALDMESERVVQDALNRV 565
Query: 1729 QAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXX 1908
RTTIIVAHRLST++N D I V + G +VE GSH ELM K Y
Sbjct: 566 MLERTTIIVAHRLSTVKNADVISVLQQGKMVEQGSHVELMKKPEGAYAQLIQLQGAQQDA 625
Query: 1909 EAGKDIEDTI----------------------------SESAHSHLXXXXXXXXXXXXXX 2004
E D D I S HS
Sbjct: 626 EIHNDDTDMIIRSDSGSRSINVKPRSQSTSFRRSITKGSSFGHSGRHPIPAPLDFPDPME 685
Query: 2005 XIHQLAEEVEECKAP----PTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAE 2172
L E K P S+ ++F N + + P+F ++ +
Sbjct: 686 FKDDLGMEETTDKVPRGQKKASISRLFYLNKPEAFVLVLGSVTAAMHGLMFPIFGILISS 745
Query: 2173 IFNVYSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNL 2352
++ P ++ + FW MFV++G + FV T G G L ++R F+++
Sbjct: 746 AIKMFYEPPSELLKDSRFWASMFVVVGASAFVLIPTEYFLFGLAGGKLVERIRSLTFRSV 805
Query: 2353 LRQDIAFYDDLRHGTGKLCTRFATDAPNV-RYVFTRLPVVLASIVTICGALGIGFYYGWQ 2529
+ Q+I ++D H +G + R + DA NV R V L + + ++ T+ I W+
Sbjct: 806 MHQEINWFDKPEHSSGSIGARLSVDALNVKRLVGDNLALNVQTVSTVISGFTIAMVANWK 865
Query: 2530 XXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQF 2709
Y +M+ G EEA +VA+ AV IRTV S +++
Sbjct: 866 LALIITVVVPLVGFQAYAQMKFLKGFNKNAKLKYEEASQVATDAVGGIRTVASFCAEQKV 925
Query: 2710 HFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYR 2889
Y + P ++ G F FS + +F YA FY+G+ FV+Q +V+R
Sbjct: 926 IEAYEKKCESPVRQGIREGVVGGLGFGFSFLVFYFTYALCFYVGAKFVHQGVATFPEVFR 985
Query: 2890 VFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIV-KPITGNIS 3066
VFF + I T++ D KA +A +F +++ + IDS S+ G+V + G+I
Sbjct: 986 VFFVLVLATSGISRTSAIGADSTKANESAVSIFEILDRKSKIDSSSEEGVVIASVRGDIE 1045
Query: 3067 IRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMI 3246
NV FNYP R + ++ + +L I +GKTVALVG SG GKST + LLERFY+ D G I++
Sbjct: 1046 FHNVCFNYPLRPNIQIFKDLSLCIPSGKTVALVGESGSGKSTAIALLERFYDPDTGKILL 1105
Query: 3247 DGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNF 3426
DG +++ +S LR Q+ +V+QEP LF+ TI NI YG + +EI+ AA+ AN H F
Sbjct: 1106 DGVDLKTFKVSWLRIQIGLVAQEPVLFNDTIHANIAYGKQEQASQEEIMAAAEAANAHQF 1165
Query: 3427 ILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEA 3606
I LPDGY T VGE+G QLSGGQKQR+AIARA+++ P VLLLDEATSALD ESE++VQEA
Sbjct: 1166 ISALPDGYSTVVGERGIQLSGGQKQRVAIARAIMKDPKVLLLDEATSALDAESERVVQEA 1225
Query: 3607 LDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIR 3741
LD GRT +V+AHRLSTI+ +D+I ++ G IVEKG HDEL+R
Sbjct: 1226 LDRVMVGRTTVVVAHRLSTIKGADIIGVLKNGAIVEKGGHDELMR 1270
Score = 330 bits (847), Expect = 1e-88
Identities = 195/540 (36%), Positives = 308/540 (56%), Gaps = 5/540 (0%)
Frame = +1
Query: 2146 PVFALVYAEIFNVY-SLPADQMQANVYFWCGMFVLMGITFFVGFFTS--ANCLGRCGESL 2316
P+ ++ ++ N + S + + A V FV +GI GF ++ +C GE
Sbjct: 74 PLMTFIFGDVINAFGSTSSPDVLAKVTKVILNFVYLGIG--AGFVSTLQVSCWTITGERQ 131
Query: 2317 TMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTIC 2493
++R K +LRQDIAF+D TG++ R + D ++ + + + + T
Sbjct: 132 AARIRALYLKAILRQDIAFFDK-EMSTGQVVERMSGDTFLIQDAIGEKSGKCIQLLSTFF 190
Query: 2494 GALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHI 2673
G I F GW + G F ++ R + +AG +A Q + I
Sbjct: 191 GGFIIAFVRGWLLALVLLSCIPPIAVAGAFVSRLMTRISTRMQEKYGDAGNIAEQTIGAI 250
Query: 2674 RTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFV 2853
RTV S N ++Q TY +++R+ + + L+ G +++F Y A + GS +
Sbjct: 251 RTVASFNGEKQAINTYNKFIRKAYESTLQEGVVNGLGLGTVMAILFCSYGLAVWYGSKLI 310
Query: 2854 NQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDS 3033
+ V V ++ +G T I + + AA +F I+ ID
Sbjct: 311 VNRGYNGGIVINVLMSVMMGAMSLGQATPSITAFAEGQGAAYRMFKTIKRQPDIDVCDTK 370
Query: 3034 GIV-KPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLE 3210
GI+ + ITG++ +++V+F+YPTR + V GF+L I +G+T+ALVG SG GKST++ L+E
Sbjct: 371 GIILEDITGDVELKDVYFSYPTRPEYLVFNGFSLQIPSGRTMALVGESGSGKSTVISLVE 430
Query: 3211 RFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEI 3390
RFY+ G ++IDG +IR +N+ +R ++ +VSQEP LF TI ENI YG + T +EI
Sbjct: 431 RFYDPQSGEVLIDGIDIRRMNLGWIRGKISLVSQEPVLFSSTIRENIAYG-KEDQTLEEI 489
Query: 3391 VEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSA 3570
A ++AN F+ LP+G +T VGE+G QLSGGQKQRIAIARA++++P +LLLDEATSA
Sbjct: 490 KRAVELANAAKFVDKLPNGLETMVGERGIQLSGGQKQRIAIARAIIKNPRILLLDEATSA 549
Query: 3571 LDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSE 3750
LD ESE++VQ+AL+ RT +++AHRLST++N+DVI+++ +GK+VE+G+H EL++K E
Sbjct: 550 LDMESERVVQDALNRVMLERTTIIVAHRLSTVKNADVISVLQQGKMVEQGSHVELMKKPE 609
>gi|50750485|ref|XP_422016.1| PREDICTED: similar to liver bile salt
export pump [Gallus gallus]
Length = 1371
Score = 807 bits (2084), Expect = 0.0
Identities = 448/1099 (40%), Positives = 655/1099 (58%), Gaps = 17/1099 (1%)
Frame = +1
Query: 529 DLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMA 708
D+ ++ E + D+ A+ +Q F+ G+ +GF W +TLV++ +PLI + A ++A
Sbjct: 295 DVNKINEAIADQVAIFIQRLTTFVCGFLLGFISGWKLTLVIIAVSPLIGVGAAVYGLAVA 354
Query: 709 TRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGI 888
T E + YA AGA+A+E SSIRTV + G K+E++R+ L + GI K MG+
Sbjct: 355 KLTGRELKAYAKAGAVADEVLSSIRTVAAFGGEKKEVERYDKNLVYAQHWGIRKGIIMGL 414
Query: 889 GVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFG 1068
G+ ++ YALAFWYGS L++ + + G + VFF VL G+ +LG A P L +F
Sbjct: 415 FSGYMWFVIFLCYALAFWYGSKLVLEEDEYSPGTLLQVFFGVLVGALNLGQASPCLEAFA 474
Query: 1069 TARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLE 1248
T RGAA+ + I+ P ID S EG +D ++G+I F +V F YPSR D+ +L IS+
Sbjct: 475 TGRGAAANIFETIDRKPTIDCMSEEGYKLDKVRGEIEFHNVTFHYPSRPDVKILDNISMV 534
Query: 1249 LKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQE 1428
+K G+ A VG+SG GKSTI+ L+QRFYDPT G + +DG D+R +N+ LR QIG+V QE
Sbjct: 535 IKTGETTAFVGASGAGKSTIIQLIQRFYDPTDGMITLDGHDIRSLNIQWLRAQIGVVEQE 594
Query: 1429 PVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQK 1608
PVLF TI ENI+ G + AT + V+ A K ANA FI LP + T VGE G Q+SGGQK
Sbjct: 595 PVLFATTIAENIRYGRDDATMEDVIRAAKQANAYKFIMDLPQQFDTHVGEGGSQMSGGQK 654
Query: 1609 QRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVD 1788
QRIAIARALV+NPKILLLD ATSALD E+E VQ AL +A GRT I +AHRLS ++ D
Sbjct: 655 QRIAIARALVRNPKILLLDMATSALDNESEAIVQEALQKAHLGRTAISIAHRLSAVKAAD 714
Query: 1789 RIFVFKAGNIVESGSHEELMSKQGIFYDM-TXXXXXXXXXXEAGKD------IEDTISES 1947
I F+ G VE G+HEEL+ ++G+++ + T A K+ +E + +
Sbjct: 715 VIIGFEHGRAVERGTHEELLKRKGVYFMLVTLQSKGDSTLTRAAKESAENKVVEPNLEKV 774
Query: 1948 AHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXX 2127
QL+ V + PP S+ GD+
Sbjct: 775 QSFRRGSYRASLRASLRQRSRSQLSNVVPD---PPLSIA------GDQA----------- 814
Query: 2128 XXXSVTPVFALVYAE-------IFNVYSLPADQMQANVYFWCGMFVLMGITFFVGFFTSA 2286
V+ Y E F++ ++Q N C +FVL+GI F F
Sbjct: 815 -----ESVYLKSYEEDDGQAKKTFSILDEEKQKVQINGV--CLLFVLVGIVSFFTQFLQG 867
Query: 2287 NCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVF-TRLP 2463
+ GE LT +LR F+ +L QD+ ++DD R+ G L TR ATDA V+ +++
Sbjct: 868 YNFAKSGELLTRRLRKIGFQAMLGQDVGWFDDRRNSPGALTTRLATDASQVQGATGSQIG 927
Query: 2464 VVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAG 2643
+++ S I A+ I FY+ W+ + G + +M G +D + LE G
Sbjct: 928 MMVNSFTNIGVAIIIAFYFSWKLSLVIMCFLPFLALSGAVQAKMLTGFAAQDKKALEATG 987
Query: 2644 KVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYA 2823
+++S+A+ +IRTV + ++++F + + L P+ +K A+ YG F F+QS++F +
Sbjct: 988 QISSEALSNIRTVAGIGKEKKFIDAFEKNLDMPYRAAIKKANVYGICFGFAQSIVFIANS 1047
Query: 2824 AAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEH 3003
++ G V + + V+RV AI G +G +S+ P+ KA+ +A+ LF LI+
Sbjct: 1048 VSYRYGGFLVQTEGLHYSFVFRVISAIVTSGTALGRASSYTPNYAKAKTSAARLFQLIDR 1107
Query: 3004 PTPIDSLSDSGIV-KPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGC 3180
I S G G+I N F YP+R D +VL+G ++ +K G+T+A VG SGC
Sbjct: 1108 LPKISVYSKEGEKWDDFKGSIEFLNCKFTYPSRPDIQVLKGLSVAVKPGQTLAFVGSSGC 1167
Query: 3181 GKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYG 3360
GKST + LLERFY+ ++G ++IDG + + +N+ LR ++ +VSQEP LFDC+I +NI YG
Sbjct: 1168 GKSTSVQLLERFYDPEEGSVLIDGHDTKKVNVQFLRSKIGVVSQEPVLFDCSIADNIKYG 1227
Query: 3361 TN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSP 3537
+N ++ T ++++EAAK A +H+F++ LP+ Y+T+VG +G+QLS GQKQRIAIARA++R P
Sbjct: 1228 SNTKDTTMEKVIEAAKKAQLHDFVMSLPEKYETNVGAQGSQLSRGQKQRIAIARAIIRDP 1287
Query: 3538 SVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEK 3717
+LLLDEATSALDTESEK VQ ALD A++GRTC+VIAHRLSTI+N+D+IA++S+G I+E+
Sbjct: 1288 KILLLDEATSALDTESEKTVQAALDKAREGRTCIVIAHRLSTIENADIIAVMSQGIIIER 1347
Query: 3718 GTHDELIRKSEIYQKFCET 3774
GTHDEL+ Y K T
Sbjct: 1348 GTHDELMAMEGAYYKLVTT 1366
Score = 414 bits (1063), Expect = e-113
Identities = 221/516 (42%), Positives = 327/516 (62%), Gaps = 4/516 (0%)
Frame = +1
Query: 340 CIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQT--GNLT 513
C+ ++++G++ FFT ++Q F E L +LR+ +A+L Q + WFD ++ G LT
Sbjct: 849 CLLFVLVGIVSFFTQFLQGYNFAKSGELLTRRLRKIGFQAMLGQDVGWFDDRRNSPGALT 908
Query: 514 ARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKM 693
RL D +V+ G + ++V F + F++SW ++LV+M F P + LSGA
Sbjct: 909 TRLATDASQVQGATGSQIGMMVNSFTNIGVAIIIAFYFSWKLSLVIMCFLPFLALSGAVQ 968
Query: 694 SKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKY 873
+K + +++ G I+ E S+IRTV + K+ +D F L++ + I K
Sbjct: 969 AKMLTGFAAQDKKALEATGQISSEALSNIRTVAGIGKEKKFIDAFEKNLDMPYRAAIKKA 1028
Query: 874 CYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPH 1053
GI GF+ ++ + ++++ YG L+ + +F V A+++ T+LG A +
Sbjct: 1029 NVYGICFGFAQSIVFIANSVSYRYGGFLVQTEG-LHYSFVFRVISAIVTSGTALGRASSY 1087
Query: 1054 LASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLK 1233
++ A+ +A+ + ++I+ PKI YS EG D+ KG I F + F YPSR DI VLK
Sbjct: 1088 TPNYAKAKTSAARLFQLIDRLPKISVYSKEGEKWDDFKGSIEFLNCKFTYPSRPDIQVLK 1147
Query: 1234 GISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIG 1413
G+S+ +K G +A VGSSGCGKST V LL+RFYDP +G VLIDG D ++VNV LR +IG
Sbjct: 1148 GLSVAVKPGQTLAFVGSSGCGKSTSVQLLERFYDPEEGSVLIDGHDTKKVNVQFLRSKIG 1207
Query: 1414 IVSQEPVLFDGTIYENIKMGN--EHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGV 1587
+VSQEPVLFD +I +NIK G+ + T ++V+EA K A +DF+ LP+ Y T VG +G
Sbjct: 1208 VVSQEPVLFDCSIADNIKYGSNTKDTTMEKVIEAAKKAQLHDFVMSLPEKYETNVGAQGS 1267
Query: 1588 QLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRL 1767
QLS GQKQRIAIARA++++PKILLLDEATSALDTE+E+ VQ ALD+A+ GRT I++AHRL
Sbjct: 1268 QLSRGQKQRIAIARAIIRDPKILLLDEATSALDTESEKTVQAALDKAREGRTCIVIAHRL 1327
Query: 1768 STIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM 1875
STI N D I V G I+E G+H+ELM+ +G +Y +
Sbjct: 1328 STIENADIIAVMSQGIIIERGTHDELMAMEGAYYKL 1363
Score = 60.8 bits (146), Expect = 2e-07
Identities = 37/168 (22%), Positives = 74/168 (44%), Gaps = 17/168 (10%)
Frame = +1
Query: 37 KPLLKRXXXXXXXXXXXTVKLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLG 216
+P +K+ V++ + +F ++ +++L+++ G+ A++HGA P + +V G
Sbjct: 54 EPSVKKKNGKSSKKKEKVVRVGFFQLFRFSSPMEILMMVVGSFCAILHGAAQPGMLLVFG 113
Query: 217 GMTTVF---------LRAQNSD-------FVVGVDNVNPEGLVP-ISLDEFNSEVVKYCI 345
M F L+ N ++ G + N + L + E+ +
Sbjct: 114 AMADTFIEYDVEMQALKDPNKTCINNTIVWINGTVHQNEKNTTTRCGLLDIEKEMTNFAA 173
Query: 346 YYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD 489
YY +G + Y QI + A R + K+R+ Y + ++R I WFD
Sbjct: 174 YYGGIGCAVLLLGYFQICFWVMAAARQIQKIRKAYFRNVMRMDIGWFD 221
>gi|39587988|emb|CAE57219.1| Hypothetical protein CBG00079
[Caenorhabditis briggsae]
Length = 1327
Score = 806 bits (2082), Expect = 0.0
Identities = 461/1256 (36%), Positives = 703/1256 (55%), Gaps = 33/1256 (2%)
Frame = +1
Query: 109 GIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPE 288
G+F Y + D LLL GT+ A+I G P++A+V G +T L
Sbjct: 92 GLFRYGKRFDYLLLFIGTICAIISGVSQPIMALVSGRVTNALL----------------- 134
Query: 289 GLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILR 468
+ P + +F ++ + +L +G+ + T+++Q CF+ R++ ++R ++ ++LR
Sbjct: 135 -VYPPTSKQFRNKANENVYIFLGIGIFISITNWIQYMCFQHCCSRVMAQMRHRFVYSVLR 193
Query: 469 QQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLV 648
Q WFDK +G +T +L D +ER+REG+GDK +L++ FA +A V + Y W + +
Sbjct: 194 QNAGWFDKNHSGTITTKLNDSMERIREGIGDKLGVLLRGFAMLIAAIVVAYIYEWRLASM 253
Query: 649 MMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRF 828
M+G AP+ + + +++ M + T E AG+IAEE+ +RTV + NG + + R+
Sbjct: 254 MLGVAPVCCICMSLLARQMTSTTIKELIGVGKAGSIAEESLMGVRTVQAFNGQEEMVGRY 313
Query: 829 YNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFF 1008
LE GR+ + K + G G LC++S YG+ L+ G +F V
Sbjct: 314 QTELEKGRRFAVWKGFWSGFFGGLFFLCLFSFLGTGMLYGAYLLKVGIIGSPGDVFIVVM 373
Query: 1009 AVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKD 1188
++L G+ LG PH+ AR +A+T+ + I+ PKIDPYS G + N+ G + F++
Sbjct: 374 SMLLGAYFLGLISPHMMVLLNARVSAATIYQTIDRVPKIDPYSKAGKRLPNVVGRVKFEN 433
Query: 1189 VHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGV 1368
VHFRYPSRK+ +L G++L ++ G +ALVG SGCGKST V LL R Y+P G V IDG
Sbjct: 434 VHFRYPSRKEAKILNGLNLTVEPGTSVALVGHSGCGKSTSVGLLTRLYEPEAGNVTIDGT 493
Query: 1369 DLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRL 1548
D+RE+N+ LR +GIV QEP+LF+ TI+ N+ +GN AT ++++E CKMANA+DFI+++
Sbjct: 494 DVRELNIDWLRNVVGIVQQEPILFNDTIHNNLLIGNPGATREKMIEVCKMANAHDFIEKM 553
Query: 1549 PDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQA 1728
P GY T +G+ GVQLSGGQKQR+AIAR L+++PKILLLDEATSALD ++E VQ AL+ A
Sbjct: 554 PKGYDTLIGDGGVQLSGGQKQRVAIARTLIRDPKILLLDEATSALDAQSESVVQSALNNA 613
Query: 1729 QAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXX------X 1890
GRTTI++AHRLSTIR D+I F+ G IVE+G+HEEL+ G ++D+
Sbjct: 614 AKGRTTIMIAHRLSTIREADKIVFFEKGVIVEAGNHEELVHLGGRYFDLVKAQQFKADPE 673
Query: 1891 XXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQL----------------- 2019
E D++D S S + ++
Sbjct: 674 ATEEFEEEEIDLDDNSRSSRRSSMTSARSGSEAFQRGNSLNDSFSGSRRSARADAENDAF 733
Query: 2020 ----AEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVY 2187
AE + + IFK + P AL++ +F +
Sbjct: 734 AAHEAEVMAQDGQITAGYLDIFKNAKGNYIYMFLGTVFALIRGLELPALALIFGWVFEGF 793
Query: 2188 SLP--ADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQ 2361
+ +M + F +G+ ++ S+ E+L+++ R ++F+NLL Q
Sbjct: 794 TFVPYGGRMMHRMAMAVIAFASVGVGVWISQVASSVLFAIVSENLSLRFRVQSFRNLLYQ 853
Query: 2362 DIAFYDDLRHGTGKLCTRFATDAPNVRYVF-TRLPVVLASIVTICGALGIGFYYGWQXX- 2535
D +++D+ H GKL TR A+DAPN++ V R+ V+ ++ I + I F Y WQ
Sbjct: 854 DASYFDNPAHAPGKLITRLASDAPNIKAVVDARMLQVIYALAAIIANIVIAFIYCWQVAI 913
Query: 2536 --XXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQF 2709
+G +++ + +QI++ +EAG+ A + +E+++T+ L R E F
Sbjct: 914 LGTSLILLLAFVMIGLAYKISLMNIEQIKN----DEAGRTAIEIIENVKTIQLLTRCELF 969
Query: 2710 HFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYR 2889
Y ++ + LK ++ +QS ++FM + +G + ++
Sbjct: 970 FDHYQTSSKQQKRSELKKGMIEAINYSITQSFMYFMMCFTYAVGIRVIYDGDKSSDVTFK 1029
Query: 2890 VFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISI 3069
++ + N+ + P+ VKA+ AA LLF +I L + G I GNI
Sbjct: 1030 GIISMMLGAVAVMNSAQYFPEFVKAKTAAGLLFNIIYRKPRTGDLME-GDRPEIRGNILF 1088
Query: 3070 RNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMID 3249
NV F+YP R +++G G+TVALVG SG GKST +G+LERFY+ G++ ID
Sbjct: 1089 ENVKFSYPQRPLQPIMKGLQWTALRGQTVALVGPSGSGKSTNIGMLERFYDVTGGVLRID 1148
Query: 3250 GDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFI 3429
G +IRNL++ LR Q+ +V QEP LF +I EN+C G ++V ++I +A ++AN + F+
Sbjct: 1149 GQDIRNLSLYHLRTQMALVGQEPRLFAGSIRENVCLGL-KDVPLEKINKALELANANRFL 1207
Query: 3430 LGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEAL 3609
LP G DT VGEKG QLSGGQKQRIAIARALVR P +LLLDEATSALD+ESE+ VQEAL
Sbjct: 1208 ANLPAGIDTDVGEKGGQLSGGQKQRIAIARALVRDPKILLLDEATSALDSESERAVQEAL 1267
Query: 3610 DAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
D A++GRTC+ IAHRLS+IQNSD+I + +GK+ E G H +L++K Y K + Q
Sbjct: 1268 DRAREGRTCITIAHRLSSIQNSDLIVYIDKGKVQEAGNHAQLMQKKGRYYKLIKKQ 1323
Score = 301 bits (770), Expect = 1e-79
Identities = 188/563 (33%), Positives = 296/563 (52%), Gaps = 18/563 (3%)
Frame = +1
Query: 2146 PVFALVYAEIFN---VYSLPADQMQ----ANVYFWCGMFVLMGITFFVGFFTSANCLGRC 2304
P+ ALV + N VY + Q + NVY + G+ + + IT ++ + C C
Sbjct: 120 PIMALVSGRVTNALLVYPPTSKQFRNKANENVYIFLGIGIFISITNWIQYM----CFQHC 175
Query: 2305 GESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASI 2481
+ ++R ++LRQ+ ++D ++ +G + T+ +R + +L V+L
Sbjct: 176 CSRVMAQMRHRFVYSVLRQNAGWFD--KNHSGTITTKLNDSMERIREGIGDKLGVLLRGF 233
Query: 2482 VTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQA 2661
+ A+ + + Y W+ + + I++ + +AG +A ++
Sbjct: 234 AMLIAAIVVAYIYEWRLASMMLGVAPVCCICMSLLARQMTSTTIKELIGVGKAGSIAEES 293
Query: 2662 VEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSL---IFFMYAAAF 2832
+ +RTV + N QE+ Y T L+ + F +FF+ +F
Sbjct: 294 LMGVRTVQAFNGQEEMVGRY--------QTELEKGRRFAVWKGFWSGFFGGLFFLCLFSF 345
Query: 2833 YLGSIFVNQQAMQ------PIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYL 2994
+ ++ P DV+ V ++ +G + + ++ AR++A+ ++
Sbjct: 346 LGTGMLYGAYLLKVGIIGSPGDVFIVVMSMLLGAYFLGLISPHMMVLLNARVSAATIYQT 405
Query: 2995 IEHPTPIDSLSDSGIVKP-ITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGH 3171
I+ ID S +G P + G + NV F YP+RK+ K+L G L ++ G +VALVGH
Sbjct: 406 IDRVPKIDPYSKAGKRLPNVVGRVKFENVHFRYPSRKEAKILNGLNLTVEPGTSVALVGH 465
Query: 3172 SGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENI 3351
SGCGKST +GLL R Y + G + IDG ++R LNI LR V IV QEP LF+ TI N+
Sbjct: 466 SGCGKSTSVGLLTRLYEPEAGNVTIDGTDVRELNIDWLRNVVGIVQQEPILFNDTIHNNL 525
Query: 3352 CYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVR 3531
G N T ++++E KMAN H+FI +P GYDT +G+ G QLSGGQKQR+AIAR L+R
Sbjct: 526 LIG-NPGATREKMIEVCKMANAHDFIEKMPKGYDTLIGDGGVQLSGGQKQRVAIARTLIR 584
Query: 3532 SPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIV 3711
P +LLLDEATSALD +SE +VQ AL+ A +GRT ++IAHRLSTI+ +D I +G IV
Sbjct: 585 DPKILLLDEATSALDAQSESVVQSALNNAAKGRTTIMIAHRLSTIREADKIVFFEKGVIV 644
Query: 3712 EKGTHDELIRKSEIYQKFCETQR 3780
E G H+EL+ Y + Q+
Sbjct: 645 EAGNHEELVHLGGRYFDLVKAQQ 667
>gi|14715462|dbj|BAB62040.1| CjMDR1 [Coptis japonica]
Length = 1289
Score = 805 bits (2079), Expect = 0.0
Identities = 464/1243 (37%), Positives = 694/1243 (55%), Gaps = 26/1243 (2%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVF-LRAQNSDFVVGVDNVN 282
Y + + D+LL++ GT+AAV +GA P++ ++LG + F A N+D + V V
Sbjct: 57 YKLLSFADSKDVLLMVIGTIAAVANGASMPVMTLLLGDLINAFGQNANNTDTLRVVSKV- 115
Query: 283 PEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAI 462
+K+ + GV FF Q+AC+ ER ++R YLK I
Sbjct: 116 ---------------ALKFVYLSIGAGVASFF----QVACWMVTGERQAARIRSLYLKTI 156
Query: 463 LRQQIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSM 639
LRQ + +FDK+ TG + R++ D +++ +G+K +Q+F+ F+ G+ + F W +
Sbjct: 157 LRQDVAFFDKETNTGEVVGRMSGDTVLIQDAIGEKVGKFIQLFSTFIGGFLIAFVKGWLL 216
Query: 640 TLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKREL 819
TLVM+ P +V GA M+ +++ Q Y+ AG + E+T SIRTV S G K +
Sbjct: 217 TLVMLTSIPPLVFCGALMTITISKMASRGQVAYSQAGIVVEQTIGSIRTVASFTGEKHAV 276
Query: 820 DRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFT 999
++ L GI + G+G+G L ++ SY+LA W+G +II + ++ G +
Sbjct: 277 TQYEKYLNKAYLAGIHEGLASGVGLGSVLLVIFCSYSLAVWFGGKMII-EKGYNGGNVIN 335
Query: 1000 VFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDIS 1179
+ AVL+GS SLG A P L +F + AA +L I P+ID Y G D+++GDI
Sbjct: 336 IIVAVLTGSMSLGQASPCLGAFAAGQAAAYKMLETIKRKPEIDSYDTSGHKSDDIRGDIE 395
Query: 1180 FKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLI 1359
+DV F YP+R D + G SL + +G ALVG SG GKST+++L++RFYDP G VLI
Sbjct: 396 LRDVSFTYPARPDEQIFNGFSLFIPSGTTSALVGQSGSGKSTVISLIERFYDPQAGEVLI 455
Query: 1360 DGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFI 1539
DGV+L++ + +R +IG+VSQEPVLF +I +NI G + AT +++ A + ANA+ FI
Sbjct: 456 DGVNLKDFQLRWIRGKIGLVSQEPVLFASSIRDNIAYGKDGATVEEIKAATERANASKFI 515
Query: 1540 KRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGAL 1719
+LP G T VGE G QLSGGQKQRIAIARA++K+P+ILLLDEATSALD E+E VQ AL
Sbjct: 516 DKLPQGLDTLVGEHGTQLSGGQKQRIAIARAILKDPRILLLDEATSALDAESEHIVQEAL 575
Query: 1720 DQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSH-EELMSKQGIFYDMTXXXXXX 1896
D+ RTT+IVAHRLST+RN D I V G IVE GSH + L++ G + +
Sbjct: 576 DRIMVNRTTVIVAHRLSTVRNADTIAVIHRGKIVEKGSHLDLLLNPDGAYCQLIRLQEIG 635
Query: 1897 XXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXX--------------IHQLAEEVE 2034
+ +++E ++ S + I++ +E
Sbjct: 636 RSEVDKAENVESGLNSSQQHSIGRSISRGSSGVGNSSRHSFSVSFGLPTGHIYETTAGLE 695
Query: 2035 ECKAPP------TSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLP 2196
P + ++ N ++ + P+F ++ + + + P
Sbjct: 696 STSPAPIGQTQEVPLRRLATLNKPEIPVLLLGVISAMVNGVIFPIFGVLLSSVIKTFYEP 755
Query: 2197 ADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFY 2376
D+++ + FW MF+++G+ FV +A G L ++R F+ + +I ++
Sbjct: 756 EDKLRKDTRFWAFMFIILGVASFVAAPATAYFFAVAGCRLIQRIRSMCFRTVAHMEIDWF 815
Query: 2377 DDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXX 2553
D+ H +G + + + DA VR V L +++ + T L I F W
Sbjct: 816 DEPEHASGAIGAKLSADASTVRGLVGDALALLVQNAATAVCGLVIAFVANWTLALIILVL 875
Query: 2554 XXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYL 2733
+ GY +M+ G + EEA +VA+ AV IRTV S +E+ Y +
Sbjct: 876 IPLIGVNGYVQMKFMKGFSADAKMMYEEASQVANDAVGSIRTVASFCAEEKVMQLYKKKC 935
Query: 2734 REPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFC 2913
P T ++ G F S L+F +YA +FY G+ V+ DV+RVFFA++
Sbjct: 936 EGPMKTGIRQGLISGIGFGISFFLLFNVYATSFYAGARLVDAGKTTFSDVFRVFFALTMA 995
Query: 2914 GQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGI-VKPITGNISIRNVFFNY 3090
I ++S PD KA+ + + +F +++ + IDS +SG+ V+ + G I +R++ F Y
Sbjct: 996 ALGISQSSSLAPDSSKAKSSTASIFGILDRKSKIDSSDESGMTVENVKGEIELRHISFKY 1055
Query: 3091 PTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNL 3270
PTR D ++ + +L I +GKTVALVG SG GKST++ LL+RFY+ D G I +DG I+
Sbjct: 1056 PTRPDIQIFRDLSLAIHSGKTVALVGESGSGKSTVISLLQRFYDPDSGHITLDGIEIQKF 1115
Query: 3271 NISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGY 3450
+ LR Q+ +VSQEP LF+ TI NI YG + T EI+ AA++AN H FI GL GY
Sbjct: 1116 QLRWLRLQMGLVSQEPVLFNETIRANIAYGKEGDATETEILAAAELANAHKFISGLQQGY 1175
Query: 3451 DTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGR 3630
DT VGE+G QLSGGQKQR+AIARA+V++P +LLLDEATSALD ESE++VQ+ALD R
Sbjct: 1176 DTVVGERGIQLSGGQKQRVAIARAMVKAPKILLLDEATSALDAESERVVQDALDKVMVNR 1235
Query: 3631 TCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIR-KSEIY 3756
T + +AHRLSTI+N+DVIA+V G I EKG H++LI K +Y
Sbjct: 1236 TTVWVAHRLSTIKNADVIAVVKNGVIAEKGKHNDLINVKDGVY 1278
Score = 296 bits (758), Expect = 3e-78
Identities = 196/556 (35%), Positives = 283/556 (50%), Gaps = 6/556 (1%)
Frame = +1
Query: 2146 PVFALVYAEIFNVYSLPADQMQAN--VYFWCGMFVLMGITFFVGFFTSANCLGRCGESLT 2319
PV L+ ++ N + A+ V FV + I V F C GE
Sbjct: 86 PVMTLLLGDLINAFGQNANNTDTLRVVSKVALKFVYLSIGAGVASFFQVACWMVTGERQA 145
Query: 2320 MKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICG 2496
++R K +LRQD+AF+D TG++ R + D ++ + ++ + T G
Sbjct: 146 ARIRSLYLKTILRQDVAFFDK-ETNTGEVVGRMSGDTVLIQDAIGEKVGKFIQLFSTFIG 204
Query: 2497 ALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLL-EEAGKVASQAVEHI 2673
I F GW G M + K Q+ +AG V Q + I
Sbjct: 205 GFLIAFVKGWLLTLVMLTSIPPLVFCGAL-MTITISKMASRGQVAYSQAGIVVEQTIGSI 263
Query: 2674 RTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFV 2853
RTV S ++ Y +YL + + + G +IF Y+ A + G +
Sbjct: 264 RTVASFTGEKHAVTQYEKYLNKAYLAGIHEGLASGVGLGSVLLVIFCSYSLAVWFGGKMI 323
Query: 2854 NQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDS 3033
++ +V + A+ +G + + + AA + I+ IDS S
Sbjct: 324 IEKGYNGGNVINIIVAVLTGSMSLGQASPCLGAFAAGQAAAYKMLETIKRKPEIDSYDTS 383
Query: 3034 GIVKP-ITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLE 3210
G I G+I +R+V F YP R D ++ GF+L I +G T ALVG SG GKST++ L+E
Sbjct: 384 GHKSDDIRGDIELRDVSFTYPARPDEQIFNGFSLFIPSGTTSALVGQSGSGKSTVISLIE 443
Query: 3211 RFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEI 3390
RFY+ G ++IDG N+++ + +R ++ +VSQEP LF +I +NI YG + T +EI
Sbjct: 444 RFYDPQAGEVLIDGVNLKDFQLRWIRGKIGLVSQEPVLFASSIRDNIAYGKD-GATVEEI 502
Query: 3391 VEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSA 3570
A + AN FI LP G DT VGE GTQLSGGQKQRIAIARA+++ P +LLLDEATSA
Sbjct: 503 KAATERANASKFIDKLPQGLDTLVGEHGTQLSGGQKQRIAIARAILKDPRILLLDEATSA 562
Query: 3571 LDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTH-DELIRKS 3747
LD ESE IVQEALD RT +++AHRLST++N+D IA++ GKIVEKG+H D L+
Sbjct: 563 LDAESEHIVQEALDRIMVNRTTVIVAHRLSTVRNADTIAVIHRGKIVEKGSHLDLLLNPD 622
Query: 3748 EIYQKFCETQRIVESQ 3795
Y + Q I S+
Sbjct: 623 GAYCQLIRLQEIGRSE 638
>gi|266518|sp|Q00449|MDR4_DROME Multidrug resistance protein homolog
49 (P-glycoprotein 49)
gi|103251|pir||A41249 multidrug resistance protein homolog Mdr49 -
fruit fly (Drosophila melanogaster)
gi|157871|gb|AAA28679.1| P glycoprotein
gi|16198339|gb|AAL14020.1| SD10012p [Drosophila melanogaster]
Length = 1302
Score = 804 bits (2076), Expect = 0.0
Identities = 475/1281 (37%), Positives = 699/1281 (54%), Gaps = 49/1281 (3%)
Frame = +1
Query: 88 TVKLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVG 267
T K + + +F Y+ + LL+ + A A P I+ G T++ + D VG
Sbjct: 26 TRKYSYFDLFRYSTRCERFLLVVSLLVATAASAFIPYFMIIYGEFTSLLV-----DRTVG 80
Query: 268 VDNVNPEGLVPI----------SLDEFNSEVVK----YCIYYLVLGVLMFFTSYVQIACF 405
V +P +P+ S +E N ++ + I LV V MF + I
Sbjct: 81 VGTSSPAFALPMFGGGQQLTNASKEENNQAIIDDATAFGIGSLVGSVAMFLLITLAIDLA 140
Query: 406 ESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQM 585
A + ++R+ +L+A+LRQ I W+D N +++T+DL++++EG+G+K ++V +
Sbjct: 141 NRIALNQIDRIRKLFLEAMLRQDIAWYDTSSGSNFASKMTEDLDKLKEGIGEKIVIVVFL 200
Query: 586 FAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEE 765
F+ G F Y W +TLV++ P I+ + + +++ + E ++Y+ A + EE
Sbjct: 201 IMTFVIGIVSAFVYGWKLTLVVLSCVPFIIAATSVVARLQGSLAEKELKSYSDAANVVEE 260
Query: 766 TFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWY 945
FS IRTV + +G ++E +RF L TG K Y G+G S L +Y ALA WY
Sbjct: 261 VFSGIRTVFAFSGQEKEKERFGKLLIPAENTGRKKGLYSGMGNALSWLIIYLCMALAIWY 320
Query: 946 GSTLIIN-----DPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVIN 1110
G TLI++ D + ++ V FAV+ G+ +LG A PH+ + A A T+ +I+
Sbjct: 321 GVTLILDERDLPDRVYTPAVLVIVLFAVIMGAQNLGFASPHVEAIAVATAAGQTLFNIID 380
Query: 1111 SHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSG 1290
++DP +G +N G I F+ + FRYP+R D+ +LKG+++++ G +A VG+SG
Sbjct: 381 RPSQVDPMDEKGNRPENTAGHIRFEGIRFRYPARPDVEILKGLTVDVLPGQTVAFVGASG 440
Query: 1291 CGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKM 1470
CGKST++ L+QRFYDP G V +DG DLR +NV LR QIG+V QEPVLF TI ENI+
Sbjct: 441 CGKSTLIQLMQRFYDPEAGSVKLDGRDLRTLNVGWLRSQIGVVGQEPVLFATTIGENIRY 500
Query: 1471 GNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPK 1650
G AT + +A + AN +DFI RLP GY T+VGEKG Q+SGGQKQRIAIARALV+ P+
Sbjct: 501 GRPSATQADIEKAARAANCHDFITRLPKGYDTQVGEKGAQISGGQKQRIAIARALVRQPQ 560
Query: 1651 ILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESG 1830
+LLLDEATSALD +E+ VQ AL+ A G TT++VAHRLSTI N D+I K G + E G
Sbjct: 561 VLLLDEATSALDPTSEKRVQSALELASQGPTTLVVAHRLSTITNADKIVFLKDGVVAEQG 620
Query: 1831 SHEELMSKQGIFYDMTXXX-------------------XXXXXXXEAGKDIEDTISESAH 1953
+HEELM ++G++ ++ E D E+ E
Sbjct: 621 THEELMERRGLYCELVSITQRKEATEADEGAVAGRPLQKSQNLSDEETDDDEEDEEEDEE 680
Query: 1954 SHLXXXXXXXXXXXXXXXIHQLAEEVEECK-----APPTSMFKIFKFNGDKVGWXXXXXX 2118
L + + + K S ++ K N + +
Sbjct: 681 PELQTSGSSRDSGFRASTRRKRRSQRRKKKKDKEVVSKVSFTQLMKLNSPEWRFIVVGGI 740
Query: 2119 XXXXXXSVTPVFALVYAEIFNVYSLPADQ-MQANVYFWCGMFVLMGITFFVGFFTSANCL 2295
+ P++ L + + F + S D ++A V +FV +G+ +G
Sbjct: 741 ASVMHGATFPLWGLFFGDFFGILSDGDDDVVRAEVLKISMIFVGIGLMAGLGNMLQTYMF 800
Query: 2296 GRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVL 2472
G +T +LR AF ++ QDIA++DD R+ G LC+R A+D NV+ R+ +L
Sbjct: 801 TTAGVKMTTRLRKRAFGTIIGQDIAYFDDERNSVGALCSRLASDCSNVQGATGARVGTML 860
Query: 2473 ASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVA 2652
++ T+ + +GF + WQ + Y E + + +EEA +VA
Sbjct: 861 QAVATLVVGMVVGFVFSWQQTLLTLVTLPLVCLSVYLEGRFIMKSAQKAKASIEEASQVA 920
Query: 2653 SQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAF 2832
+A+ +IRTV+ L + Q Y + + + G VFA Q+ F Y +
Sbjct: 921 VEAITNIRTVNGLCLERQVLDQYVQQIDRVDVACRRKVRFRGLVFALGQAAPFLAYGISM 980
Query: 2833 YLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPT- 3009
Y G I V ++ M D+ +V A+ F M+G ++ P+V A L+A L L + +
Sbjct: 981 YYGGILVAEERMNYEDIIKVAEALIFGSWMLGQALAYAPNVNDAILSAGRLMDLFKRTST 1040
Query: 3010 -PIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGK 3186
P S V+ G+I NV F YPTRK T +LQG L IK TVALVG SG GK
Sbjct: 1041 QPNPPQSPYNTVEKSEGDIVYENVGFEYPTRKGTPILQGLNLTIKKSTTVALVGPSGSGK 1100
Query: 3187 STIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTN 3366
ST + LL R+Y+ G + + G + +LR ++ +VSQEP LFD TI ENI YG N
Sbjct: 1101 STCVQLLLRYYDPVSGSVNLSGVPSTEFPLDTLRSKLGLVSQEPVLFDRTIAENIAYGNN 1160
Query: 3367 --RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPS 3540
+V+ QEI+EAAK +NIHNFI LP GYDT +G K +QLSGGQKQRIAIARALVR+P
Sbjct: 1161 FRDDVSMQEIIEAAKKSNIHNFISALPQGYDTRLG-KTSQLSGGQKQRIAIARALVRNPK 1219
Query: 3541 VLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKG 3720
+L+LDEATSALD ESEK+VQ+ALD A+ GRTCL IAHRL+T++N+D+I ++ G +VE G
Sbjct: 1220 ILILDEATSALDLESEKVVQQALDEARSGRTCLTIAHRLTTVRNADLICVLKRGVVVEHG 1279
Query: 3721 THDELIRKSEIYQKFCETQRI 3783
THDEL+ ++IY Q++
Sbjct: 1280 THDELMALNKIYANLYLMQQV 1300
Score = 312 bits (800), Expect = 3e-83
Identities = 191/497 (38%), Positives = 273/497 (54%), Gaps = 8/497 (1%)
Frame = +1
Query: 2323 KLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIVTICGA 2499
KL EA +LRQDIA+YD ++ D ++ + ++ +V+ I+T
Sbjct: 153 KLFLEA---MLRQDIAWYDT--SSGSNFASKMTEDLDKLKEGIGEKIVIVVFLIMTFVIG 207
Query: 2500 LGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRT 2679
+ F YGW+ +++ ++ + +A V + IRT
Sbjct: 208 IVSAFVYGWKLTLVVLSCVPFIIAATSVVARLQGSLAEKELKSYSDAANVVEEVFSGIRT 267
Query: 2680 VHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQ 2859
V + + QE+ + + L NT K G A S +I+ A A + G +
Sbjct: 268 VFAFSGQEKEKERFGKLLIPAENTGRKKGLYSGMGNALSWLIIYLCMALAIWYGVTLILD 327
Query: 2860 QAMQPIDVYR------VFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDS 3021
+ P VY V FA+ Q +G + + + A A LF +I+ P+ +D
Sbjct: 328 ERDLPDRVYTPAVLVIVLFAVIMGAQNLGFASPHVEAIAVATAAGQTLFNIIDRPSQVDP 387
Query: 3022 LSDSGIVKPIT-GNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIM 3198
+ + G T G+I + F YP R D ++L+G T+D+ G+TVA VG SGCGKST++
Sbjct: 388 MDEKGNRPENTAGHIRFEGIRFRYPARPDVEILKGLTVDVLPGQTVAFVGASGCGKSTLI 447
Query: 3199 GLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVT 3378
L++RFY+ + G + +DG ++R LN+ LR Q+ +V QEP LF TIGENI YG + T
Sbjct: 448 QLMQRFYDPEAGSVKLDGRDLRTLNVGWLRSQIGVVGQEPVLFATTIGENIRYG-RPSAT 506
Query: 3379 YQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDE 3558
+I +AA+ AN H+FI LP GYDT VGEKG Q+SGGQKQRIAIARALVR P VLLLDE
Sbjct: 507 QADIEKAARAANCHDFITRLPKGYDTQVGEKGAQISGGQKQRIAIARALVRQPQVLLLDE 566
Query: 3559 ATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELI 3738
ATSALD SEK VQ AL+ A QG T LV+AHRLSTI N+D I + +G + E+GTH+EL+
Sbjct: 567 ATSALDPTSEKRVQSALELASQGPTTLVVAHRLSTITNADKIVFLKDGVVAEQGTHEELM 626
Query: 3739 RKSEIYQKFCETQRIVE 3789
+ +Y CE I +
Sbjct: 627 ERRGLY---CELVSITQ 640
>gi|24653245|ref|NP_523724.2| CG3879-PA [Drosophila melanogaster]
gi|21627300|gb|AAF58437.2| CG3879-PA [Drosophila melanogaster]
Length = 1302
Score = 804 bits (2076), Expect = 0.0
Identities = 475/1281 (37%), Positives = 699/1281 (54%), Gaps = 49/1281 (3%)
Frame = +1
Query: 88 TVKLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVG 267
T K + + +F Y+ + LL+ + A A P I+ G T++ + D VG
Sbjct: 26 TRKYSYFDLFRYSTRCERFLLVVSLLVATAASAFIPYFMIIYGEFTSLLV-----DRTVG 80
Query: 268 VDNVNPEGLVPI----------SLDEFNSEVVK----YCIYYLVLGVLMFFTSYVQIACF 405
V +P +P+ S +E N ++ + I LV V MF + I
Sbjct: 81 VGTSSPAFALPMFGGGQQLTNASKEENNQAIIDDATAFGIGSLVGSVAMFLLITLAIDLA 140
Query: 406 ESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQM 585
A + ++R+ +L+A+LRQ I W+D N +++T+DL++++EG+G+K ++V +
Sbjct: 141 NRIALNQIDRIRKLFLEAMLRQDIAWYDTSSGSNFASKMTEDLDKLKEGIGEKIVIVVFL 200
Query: 586 FAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEE 765
F+ G F Y W +TLV++ P I+ + + +++ + E ++Y+ A + EE
Sbjct: 201 IMTFVIGIVSAFVYGWKLTLVVLSCVPFIIAATSVVARLQGSLAEKELKSYSDAANVVEE 260
Query: 766 TFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWY 945
FS IRTV + +G ++E +RF L TG K Y G+G S L +Y ALA WY
Sbjct: 261 VFSGIRTVFAFSGQEKEKERFGKLLIPAENTGRKKGLYSGMGNALSWLIIYLCMALAIWY 320
Query: 946 GSTLIIN-----DPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVIN 1110
G TLI++ D + ++ V FAV+ G+ +LG A PH+ + A A T+ +I+
Sbjct: 321 GVTLILDERDLPDRVYTPAVLVIVLFAVIMGAQNLGFASPHVEAIAVATAAGQTLFNIID 380
Query: 1111 SHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSG 1290
++DP +G +N G I F+ + FRYP+R D+ +LKG+++++ G +A VG+SG
Sbjct: 381 RPSQVDPMDEKGNRPENTAGHIRFEGIRFRYPARPDVEILKGLTVDVLPGQTVAFVGASG 440
Query: 1291 CGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKM 1470
CGKST++ L+QRFYDP G V +DG DLR +NV LR QIG+V QEPVLF TI ENI+
Sbjct: 441 CGKSTLIQLMQRFYDPEAGSVKLDGRDLRTLNVGWLRSQIGVVGQEPVLFATTIGENIRY 500
Query: 1471 GNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPK 1650
G AT + +A + AN +DFI RLP GY T+VGEKG Q+SGGQKQRIAIARALV+ P+
Sbjct: 501 GRPSATQADIEKAARAANCHDFITRLPKGYDTQVGEKGAQISGGQKQRIAIARALVRQPQ 560
Query: 1651 ILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESG 1830
+LLLDEATSALD +E+ VQ AL+ A G TT++VAHRLSTI N D+I K G + E G
Sbjct: 561 VLLLDEATSALDPTSEKRVQSALELASQGPTTLVVAHRLSTITNADKIVFLKDGVVAEQG 620
Query: 1831 SHEELMSKQGIFYDMTXXX-------------------XXXXXXXEAGKDIEDTISESAH 1953
+HEELM ++G++ ++ E D E+ E
Sbjct: 621 THEELMERRGLYCELVSITQRKEATEADEGAVAGRPLQKSQNLSDEETDDDEEDEEEDEE 680
Query: 1954 SHLXXXXXXXXXXXXXXXIHQLAEEVEECK-----APPTSMFKIFKFNGDKVGWXXXXXX 2118
L + + + K S ++ K N + +
Sbjct: 681 PELQTSGSSRDSGFRASTRRKRRSQRRKKKKDKEVVSKVSFTQLMKLNSPEWRFIVVGGI 740
Query: 2119 XXXXXXSVTPVFALVYAEIFNVYSLPADQ-MQANVYFWCGMFVLMGITFFVGFFTSANCL 2295
+ P++ L + + F + S D ++A V +FV +G+ +G
Sbjct: 741 ASVMHGATFPLWGLFFGDFFGILSDGDDDVVRAEVLKISMIFVGIGLMAGLGNMLQTYMF 800
Query: 2296 GRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVL 2472
G +T +LR AF ++ QDIA++DD R+ G LC+R A+D NV+ R+ +L
Sbjct: 801 TTAGVKMTTRLRKRAFGTIIGQDIAYFDDERNSVGALCSRLASDCSNVQGATGARVGTML 860
Query: 2473 ASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVA 2652
++ T+ + +GF + WQ + Y E + + +EEA +VA
Sbjct: 861 QAVATLVVGMVVGFVFSWQQTLLTLVTLPLVCLSVYLEGRFIMKSAQKAKASIEEASQVA 920
Query: 2653 SQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAF 2832
+A+ +IRTV+ L + Q Y + + + G VFA Q+ F Y +
Sbjct: 921 VEAITNIRTVNGLCLERQVLDQYVQQIDRVDIACRRKVRFRGLVFALGQAAPFLAYGISM 980
Query: 2833 YLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPT- 3009
Y G I V ++ M D+ +V A+ F M+G ++ P+V A L+A L L + +
Sbjct: 981 YYGGILVAEERMNYEDIIKVAEALIFGSWMLGQALAYAPNVNDAILSAGRLMDLFKRTST 1040
Query: 3010 -PIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGK 3186
P S V+ G+I NV F YPTRK T +LQG L IK TVALVG SG GK
Sbjct: 1041 QPNPPQSPYNTVEKSEGDIVYENVGFEYPTRKGTPILQGLNLTIKKSTTVALVGPSGSGK 1100
Query: 3187 STIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTN 3366
ST + LL R+Y+ G + + G + +LR ++ +VSQEP LFD TI ENI YG N
Sbjct: 1101 STCVQLLLRYYDPVSGSVNLSGVPSTEFPLDTLRSKLGLVSQEPVLFDRTIAENIAYGNN 1160
Query: 3367 --RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPS 3540
+V+ QEI+EAAK +NIHNFI LP GYDT +G K +QLSGGQKQRIAIARALVR+P
Sbjct: 1161 FRDDVSMQEIIEAAKKSNIHNFISALPQGYDTRLG-KTSQLSGGQKQRIAIARALVRNPK 1219
Query: 3541 VLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKG 3720
+L+LDEATSALD ESEK+VQ+ALD A+ GRTCL IAHRL+T++N+D+I ++ G +VE G
Sbjct: 1220 ILILDEATSALDLESEKVVQQALDEARSGRTCLTIAHRLTTVRNADLICVLKRGVVVEHG 1279
Query: 3721 THDELIRKSEIYQKFCETQRI 3783
THDEL+ ++IY Q++
Sbjct: 1280 THDELMALNKIYANLYLMQQV 1300
Score = 312 bits (800), Expect = 3e-83
Identities = 191/497 (38%), Positives = 273/497 (54%), Gaps = 8/497 (1%)
Frame = +1
Query: 2323 KLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIVTICGA 2499
KL EA +LRQDIA+YD ++ D ++ + ++ +V+ I+T
Sbjct: 153 KLFLEA---MLRQDIAWYDT--SSGSNFASKMTEDLDKLKEGIGEKIVIVVFLIMTFVIG 207
Query: 2500 LGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRT 2679
+ F YGW+ +++ ++ + +A V + IRT
Sbjct: 208 IVSAFVYGWKLTLVVLSCVPFIIAATSVVARLQGSLAEKELKSYSDAANVVEEVFSGIRT 267
Query: 2680 VHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQ 2859
V + + QE+ + + L NT K G A S +I+ A A + G +
Sbjct: 268 VFAFSGQEKEKERFGKLLIPAENTGRKKGLYSGMGNALSWLIIYLCMALAIWYGVTLILD 327
Query: 2860 QAMQPIDVYR------VFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDS 3021
+ P VY V FA+ Q +G + + + A A LF +I+ P+ +D
Sbjct: 328 ERDLPDRVYTPAVLVIVLFAVIMGAQNLGFASPHVEAIAVATAAGQTLFNIIDRPSQVDP 387
Query: 3022 LSDSGIVKPIT-GNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIM 3198
+ + G T G+I + F YP R D ++L+G T+D+ G+TVA VG SGCGKST++
Sbjct: 388 MDEKGNRPENTAGHIRFEGIRFRYPARPDVEILKGLTVDVLPGQTVAFVGASGCGKSTLI 447
Query: 3199 GLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVT 3378
L++RFY+ + G + +DG ++R LN+ LR Q+ +V QEP LF TIGENI YG + T
Sbjct: 448 QLMQRFYDPEAGSVKLDGRDLRTLNVGWLRSQIGVVGQEPVLFATTIGENIRYG-RPSAT 506
Query: 3379 YQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDE 3558
+I +AA+ AN H+FI LP GYDT VGEKG Q+SGGQKQRIAIARALVR P VLLLDE
Sbjct: 507 QADIEKAARAANCHDFITRLPKGYDTQVGEKGAQISGGQKQRIAIARALVRQPQVLLLDE 566
Query: 3559 ATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELI 3738
ATSALD SEK VQ AL+ A QG T LV+AHRLSTI N+D I + +G + E+GTH+EL+
Sbjct: 567 ATSALDPTSEKRVQSALELASQGPTTLVVAHRLSTITNADKIVFLKDGVVAEQGTHEELM 626
Query: 3739 RKSEIYQKFCETQRIVE 3789
+ +Y CE I +
Sbjct: 627 ERRGLY---CELVSITQ 640
>gi|17567269|ref|NP_510128.1| P-GlycoProtein related (146.8 kD)
(pgp-14) [Caenorhabditis elegans]
gi|7499665|pir||T21268 hypothetical protein F22E10.3 - Caenorhabditis
elegans
gi|3876293|emb|CAA91801.1| Hypothetical protein F22E10.3
[Caenorhabditis elegans]
gi|40764042|gb|AAR89639.1| P-glycoprotein related (146.8 kD) (pgp-14)
[Caenorhabditis elegans]
Length = 1327
Score = 802 bits (2072), Expect = 0.0
Identities = 460/1256 (36%), Positives = 698/1256 (54%), Gaps = 33/1256 (2%)
Frame = +1
Query: 109 GIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPE 288
G+F Y + D LLL GT+ A+I G P+LA+V G +T L
Sbjct: 92 GLFRYGKKFDYLLLFIGTICAIISGVSQPILALVSGRVTNALL----------------- 134
Query: 289 GLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILR 468
+ P + +F ++ + +L +G+ + T+++Q CF+ R++ ++R ++ ++LR
Sbjct: 135 -VYPPTSKQFRNKANENVYIFLGIGIFISITNFIQYMCFQHCCTRVMAQMRHRFVYSVLR 193
Query: 469 QQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLV 648
Q WFDK +G +T +L D +ER+REG+GDK +L++ FA +A V + Y W + +
Sbjct: 194 QNAGWFDKNHSGTITTKLNDSMERIREGIGDKLGVLLRGFAMLIAAIVVAYIYEWRLASM 253
Query: 649 MMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRF 828
M+G AP + + +++ M + T E AG+IAEE+ +RTV + NG + + R+
Sbjct: 254 MLGVAPTCCICMSLLARQMTSTTIKELIGVGKAGSIAEESLMGVRTVQAFNGQEEMVGRY 313
Query: 829 YNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFF 1008
LE GR+ + K + G G ++S YG+ L+ G +F V
Sbjct: 314 EAELEKGRKFAVWKGFWSGFFGGLFFFWLFSFLGCGMLYGAYLLKVGIITTPGDVFIVVM 373
Query: 1009 AVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKD 1188
++L G+ LG PH+ AR +A+++ + I+ PKIDPYS G + N+ G + F++
Sbjct: 374 SMLLGAYFLGLISPHMMVLLNARVSAASIYQTIDRVPKIDPYSKAGKRLQNVVGRVKFEN 433
Query: 1189 VHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGV 1368
VHFRYPSRKD +L G++L ++ G +ALVG SGCGKST V LL R Y+P G V IDG
Sbjct: 434 VHFRYPSRKDAKILNGLNLVVEPGTSVALVGHSGCGKSTSVGLLTRLYEPEAGNVTIDGT 493
Query: 1369 DLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRL 1548
D+RE+N+ LR +GIV QEP+LF+ TI+ N+ +GN +T + ++E CKMANA+DFI+++
Sbjct: 494 DVRELNIEWLRNTVGIVQQEPILFNDTIHNNLLIGNPGSTRETMIEVCKMANAHDFIEKM 553
Query: 1549 PDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQA 1728
P GY T +G+ GVQLSGGQKQR+AIAR L+++PK+LLLDEATSALD ++E VQ AL+ A
Sbjct: 554 PKGYDTLIGDGGVQLSGGQKQRVAIARTLIRDPKVLLLDEATSALDAQSESIVQSALNNA 613
Query: 1729 QAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXX------X 1890
GRTTI++AHRLSTIR D+I F+ G IVE+G+HEEL+ G ++D+
Sbjct: 614 SKGRTTIMIAHRLSTIREADKIVFFEKGVIVEAGNHEELVRLGGRYFDLVKAQQFKADPE 673
Query: 1891 XXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQL----------------- 2019
E D++DT S S + ++
Sbjct: 674 ATEEFEEEEIDLDDTSRSSRRSSMTSARSGSEAFRRGNSLNDSFSGSKRSAQADAENSAF 733
Query: 2020 ----AEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVY 2187
A + E IFK + P AL++ +F +
Sbjct: 734 AANEAAIMAEDGQITAGYLDIFKNAKGNYLYMFLGTVFALIRGLELPALALIFGWVFEGF 793
Query: 2188 SLP--ADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQ 2361
+ +M + F +G+ + S+ E+L+M+ R ++F+NLL Q
Sbjct: 794 TFVPYGGRMMHRMAMAVIAFASVGVGVWFSQLASSVLFAVVSENLSMRFRVQSFRNLLYQ 853
Query: 2362 DIAFYDDLRHGTGKLCTRFATDAPNVRYVF-TRLPVVLASIVTICGALGIGFYYGWQ--- 2529
D +++D+ H GKL TR A+DAPN++ V R+ V+ ++ I + I F Y WQ
Sbjct: 854 DASYFDNPAHAPGKLITRLASDAPNIKAVVDARMLQVIYALAAIIANIAIAFIYCWQIGI 913
Query: 2530 XXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQF 2709
+G +++ + +QI++ ++AG++A + +E+++T+ L R E F
Sbjct: 914 LGTSLILLLAFVMIGLAYKISLMNVEQIQN----DDAGRIAIEIIENVKTIQLLTRCELF 969
Query: 2710 HFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYR 2889
Y ++ + LK ++ +QS ++FM + +G + Q D ++
Sbjct: 970 FDHYQTSSKQQKRSELKKGMIEAINYSLTQSFMYFMMCFTYAVGIRIIYQGDKSSDDTFK 1029
Query: 2890 VFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISI 3069
A+ + N+ + P+ VKA+ AA +LF +I L + G I GNI
Sbjct: 1030 GIIAMMLGAVAVMNSAQYFPEFVKAKTAAGMLFNIIYRKPRTGDLME-GDRPEIRGNILF 1088
Query: 3070 RNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMID 3249
NV F+YP R +++G G+TVALVG SG GKST +G+LERFY+ G + ID
Sbjct: 1089 ENVKFSYPQRPLQPIMKGLQWTALRGQTVALVGPSGSGKSTNIGMLERFYDVTGGALRID 1148
Query: 3250 GDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFI 3429
G +IR L++ LR Q+ +V QEP LF TI EN+C G ++V ++I +A ++AN + F+
Sbjct: 1149 GQDIRKLSLFHLRTQMALVGQEPRLFAGTIRENVCLGL-KDVPLEKINQALELANANRFL 1207
Query: 3430 LGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEAL 3609
LP G DT VGEKG QLSGGQKQRIAIARALVR P +LLLDEATSALD+ESE+ VQEAL
Sbjct: 1208 ANLPAGIDTDVGEKGGQLSGGQKQRIAIARALVRDPKILLLDEATSALDSESERAVQEAL 1267
Query: 3610 DAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
D A++GRTC+ IAHRLS+IQNSD+I + +GK+ E G H +L+ + Y K + Q
Sbjct: 1268 DRAREGRTCITIAHRLSSIQNSDLIVYIDKGKVQEAGNHTQLMHQKGRYYKLIKKQ 1323
Score = 306 bits (784), Expect = 2e-81
Identities = 202/599 (33%), Positives = 311/599 (51%), Gaps = 16/599 (2%)
Frame = +1
Query: 2032 EECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVT--PVFALVYAEIFN---VYSLP 2196
++ +A P S+ +F++ G K + S P+ ALV + N VY
Sbjct: 81 QQLEAQPVSIPGLFRY-GKKFDYLLLFIGTICAIISGVSQPILALVSGRVTNALLVYPPT 139
Query: 2197 ADQMQ----ANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQD 2364
+ Q + NVY + G+ + + IT F+ + C C + ++R ++LRQ+
Sbjct: 140 SKQFRNKANENVYIFLGIGIFISITNFIQYM----CFQHCCTRVMAQMRHRFVYSVLRQN 195
Query: 2365 IAFYDDLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIVTICGALGIGFYYGWQXXXX 2541
++D ++ +G + T+ +R + +L V+L + A+ + + Y W+
Sbjct: 196 AGWFD--KNHSGTITTKLNDSMERIREGIGDKLGVLLRGFAMLIAAIVVAYIYEWRLASM 253
Query: 2542 XXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTY 2721
+ + I++ + +AG +A +++ +RTV + N QE+ Y
Sbjct: 254 MLGVAPTCCICMSLLARQMTSTTIKELIGVGKAGSIAEESLMGVRTVQAFNGQEEMVGRY 313
Query: 2722 CEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAM-----QPIDVY 2886
L + K A G F L FF + G ++ P DV+
Sbjct: 314 EAELEK----GRKFAVWKGFWSGFFGGLFFFWLFSFLGCGMLYGAYLLKVGIITTPGDVF 369
Query: 2887 RVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGI-VKPITGNI 3063
V ++ +G + + ++ AR++A+ ++ I+ ID S +G ++ + G +
Sbjct: 370 IVVMSMLLGAYFLGLISPHMMVLLNARVSAASIYQTIDRVPKIDPYSKAGKRLQNVVGRV 429
Query: 3064 SIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIM 3243
NV F YP+RKD K+L G L ++ G +VALVGHSGCGKST +GLL R Y + G +
Sbjct: 430 KFENVHFRYPSRKDAKILNGLNLVVEPGTSVALVGHSGCGKSTSVGLLTRLYEPEAGNVT 489
Query: 3244 IDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHN 3423
IDG ++R LNI LR V IV QEP LF+ TI N+ G N T + ++E KMAN H+
Sbjct: 490 IDGTDVRELNIEWLRNTVGIVQQEPILFNDTIHNNLLIG-NPGSTRETMIEVCKMANAHD 548
Query: 3424 FILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQE 3603
FI +P GYDT +G+ G QLSGGQKQR+AIAR L+R P VLLLDEATSALD +SE IVQ
Sbjct: 549 FIEKMPKGYDTLIGDGGVQLSGGQKQRVAIARTLIRDPKVLLLDEATSALDAQSESIVQS 608
Query: 3604 ALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQR 3780
AL+ A +GRT ++IAHRLSTI+ +D I +G IVE G H+EL+R Y + Q+
Sbjct: 609 ALNNASKGRTTIMIAHRLSTIREADKIVFFEKGVIVEAGNHEELVRLGGRYFDLVKAQQ 667
>gi|15217786|ref|NP_171754.1| multidrug resistance P-glycoprotein,
putative [Arabidopsis thaliana]
Length = 1273
Score = 802 bits (2071), Expect = 0.0
Identities = 455/1245 (36%), Positives = 689/1245 (54%), Gaps = 33/1245 (2%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNP 285
Y +F + D+ L+I G++ A+ +G PL+ ++ G + F + QN+ +V V
Sbjct: 31 YKLFAFADSFDVFLMICGSLGAIGNGVCLPLMTLLFGDLIDSFGKNQNNKDIVDV----- 85
Query: 286 EGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAIL 465
V K C+ ++ LG+ +++Q+AC+ ER K+R NYLK IL
Sbjct: 86 --------------VSKVCLKFVYLGLGRLGAAFLQVACWMITGERQAAKIRSNYLKTIL 131
Query: 466 RQQIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMT 642
RQ I +FD + TG + R++ D +++ +G+K +Q+ + F+ G+ + F W +T
Sbjct: 132 RQDIGFFDVETNTGEVVGRMSGDTVHIQDAMGEKVGKFIQLVSTFVGGFALAFAKGWLLT 191
Query: 643 LVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELD 822
LVM+ P + ++GA M+ + + Q YA A + E+T SIRTV S G K+ ++
Sbjct: 192 LVMLTSIPFLAMAGAAMALLVTRASSRGQAAYAKAATVVEQTIGSIRTVASFTGEKQAIN 251
Query: 823 RFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTV 1002
+ + ++ I + G+G+G +SSYALA W+G +I+ + + G + V
Sbjct: 252 SYKKYITSAYKSSIQQGFSTGLGLGVMIYVFFSSYALAIWFGGKMIL-EKGYTGGSVINV 310
Query: 1003 FFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISF 1182
V++GS SLG P + +F + AA + I P ID Y + G ++ +++GDI
Sbjct: 311 IIIVVAGSMSLGQTSPCVTAFAAGQAAAYKMFETIKRKPLIDAYDVNGKVLGDIRGDIEL 370
Query: 1183 KDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLID 1362
KDVHF YP+R D + G SL + +G ALVG SG GKST++NL++RFYDP G VLID
Sbjct: 371 KDVHFSYPARPDEEIFDGFSLFIPSGATAALVGESGSGKSTVINLIERFYDPKAGEVLID 430
Query: 1363 GVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIK 1542
G++L+E + +R +IG+V QEPVLF +I ENI G E+AT ++ A ++ANA FI
Sbjct: 431 GINLKEFQLKWIRSKIGLVCQEPVLFSSSIMENIAYGKENATLQEIKVATELANAAKFIN 490
Query: 1543 RLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALD 1722
LP G T+VGE G QLSGGQKQRIAIARA++K+P++LLLDEATSALDTE+ER VQ ALD
Sbjct: 491 NLPQGLDTKVGEHGTQLSGGQKQRIAIARAILKDPRVLLLDEATSALDTESERVVQEALD 550
Query: 1723 QAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXX 1902
+ RTT++VAHRLST+RN D I V +G +VE GSH EL+ Y
Sbjct: 551 RVMVNRTTVVVAHRLSTVRNADMIAVIHSGKMVEKGSHSELLKDSVGAYSQLIRCQEINK 610
Query: 1903 XXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXI------HQL--------------- 2019
+A + S +S+L H L
Sbjct: 611 GHDAKPSDMASGSSFRNSNLNISREGSVISGGTSSFGNSSRHHSLNVLGLFAGLDLGSGS 670
Query: 2020 ----AEEVEECKAPP---TSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIF 2178
EE P S+ +I N ++ ++ P+F ++ + +
Sbjct: 671 QRVGQEETGTTSQEPLRKVSLTRIAALNKPEIPVLLLGTVVAAINGAIFPLFGILISRVI 730
Query: 2179 NVYSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLR 2358
+ PADQ++ + FW +FV +G+T + + G L +++ F+ +
Sbjct: 731 EAFFKPADQLKKDSRFWAIIFVALGVTSLIVSPSQMYLFAVAGGKLIRRIQSMCFEKAVH 790
Query: 2359 QDIAFYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXX 2535
+++++D+ + +G + R +TDA +R V L + + + + L I F W+
Sbjct: 791 MEVSWFDEPENSSGTMGARLSTDAALIRALVGDALSLAVQNAASAASGLIIAFTASWELA 850
Query: 2536 XXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHF 2715
+ G+ +++ G EEA +VA+ AV IRTV S +E+
Sbjct: 851 LIILVMLPLIGINGFLQVKFMKGFSADAKSKYEEASQVANDAVGSIRTVASFCAEEKVMQ 910
Query: 2716 TYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVF 2895
Y + P +K G F FS ++F +YA +FY + V IDV++VF
Sbjct: 911 MYNKQCEGPIKDGVKQGFISGLGFGFSFFILFCVYATSFYAAARLVEDGKTTFIDVFQVF 970
Query: 2896 FAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIR 3072
FA++ I +++F PD KA++AA+ +F +I+ + IDS ++G +++ + G+I +R
Sbjct: 971 FALTMAAIGISQSSTFAPDSSKAKVAAASIFAIIDRKSKIDSSDETGTVLENVKGDIELR 1030
Query: 3073 NVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDG 3252
++ F YP R ++ + L I+AGKTVALVG SG GKST++ LL+RFY+ D G I +DG
Sbjct: 1031 HLSFTYPARPGIQIFRDLCLTIRAGKTVALVGESGSGKSTVISLLQRFYDPDSGQITLDG 1090
Query: 3253 DNIRNLNISSLREQVCIVSQEPTLFDCTIGENICY--GTNRNVTYQEIVEAAKMANIHNF 3426
++ L + LR+Q+ +V QEP LF+ TI NI Y G+ T EI+ AA++AN H F
Sbjct: 1091 VELKKLQLKWLRQQMGLVGQEPVLFNDTIRANIAYGKGSEEAATESEIIAAAELANAHKF 1150
Query: 3427 ILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEA 3606
I + GYDT VGEKG QLSGGQKQR+AIARA+V+ P +LLLDEATSALD ESE++VQ+A
Sbjct: 1151 ISSIQQGYDTVVGEKGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERLVQDA 1210
Query: 3607 LDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIR 3741
LD RT +V+AHRLSTI+N+DVIAIV G I E GTH+ LI+
Sbjct: 1211 LDRVIVNRTTVVVAHRLSTIKNADVIAIVKNGVIAENGTHETLIK 1255
Score = 375 bits (964), Expect = e-102
Identities = 213/583 (36%), Positives = 330/583 (56%), Gaps = 5/583 (0%)
Frame = +1
Query: 136 DLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDE 315
++ +L+ GTV A I+GA FPL I++ + F + D+
Sbjct: 701 EIPVLLLGTVVAAINGAIFPLFGILISRVIEAFFKPA---------------------DQ 739
Query: 316 FNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQ 495
+ + I ++ LGV S Q+ F +L+ +++ + + ++ WFD+
Sbjct: 740 LKKDSRFWAIIFVALGVTSLIVSPSQMYLFAVAGGKLIRRIQSMCFEKAVHMEVSWFDEP 799
Query: 496 Q--TGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPL 669
+ +G + ARL+ D +R +GD +L VQ A+ +G + F SW + L+++ PL
Sbjct: 800 ENSSGTMGARLSTDAALIRALVGDALSLAVQNAASAASGLIIAFTASWELALIILVMLPL 859
Query: 670 IVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVG 849
I ++G K M + + Y A +A + SIRTV S ++ + + E
Sbjct: 860 IGINGFLQVKFMKGFSADAKSKYEEASQVANDAVGSIRTVASFCAEEKVMQMYNKQCEGP 919
Query: 850 RQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGST 1029
+ G+ + G+G GFS ++ YA +F Y + ++ D +F VFFA+ +
Sbjct: 920 IKDGVKQGFISGLGFGFSFFILFCVYATSF-YAAARLVEDGKTTFIDVFQVFFALTMAAI 978
Query: 1030 SLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPS 1209
+ + A+ AA+++ +I+ KID G +++N+KGDI + + F YP+
Sbjct: 979 GISQSSTFAPDSSKAKVAAASIFAIIDRKSKIDSSDETGTVLENVKGDIELRHLSFTYPA 1038
Query: 1210 RKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNV 1389
R I + + + L ++AG +ALVG SG GKST+++LLQRFYDP G++ +DGV+L+++ +
Sbjct: 1039 RPGIQIFRDLCLTIRAGKTVALVGESGSGKSTVISLLQRFYDPDSGQITLDGVELKKLQL 1098
Query: 1390 HSLREQIGIVSQEPVLFDGTIYENIKMGN---EHATHDQVVEACKMANANDFIKRLPDGY 1560
LR+Q+G+V QEPVLF+ TI NI G E AT +++ A ++ANA+ FI + GY
Sbjct: 1099 KWLRQQMGLVGQEPVLFNDTIRANIAYGKGSEEAATESEIIAAAELANAHKFISSIQQGY 1158
Query: 1561 GTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGR 1740
T VGEKG+QLSGGQKQR+AIARA+VK PKILLLDEATSALD E+ER VQ ALD+ R
Sbjct: 1159 DTVVGEKGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERLVQDALDRVIVNR 1218
Query: 1741 TTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFY 1869
TT++VAHRLSTI+N D I + K G I E+G+HE L+ G Y
Sbjct: 1219 TTVVVAHRLSTIKNADVIAIVKNGVIAENGTHETLIKIDGGVY 1261
Score = 322 bits (826), Expect = 3e-86
Identities = 187/508 (36%), Positives = 276/508 (53%), Gaps = 2/508 (0%)
Frame = +1
Query: 2230 CGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLC 2409
C FV +G+ F C GE K+R K +LRQDI F+D + TG++
Sbjct: 90 CLKFVYLGLGRLGAAFLQVACWMITGERQAAKIRSNYLKTILRQDIGFFD-VETNTGEVV 148
Query: 2410 TRFATDAPNVRYVF-TRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFE 2586
R + D +++ ++ + + T G + F GW M G
Sbjct: 149 GRMSGDTVHIQDAMGEKVGKFIQLVSTFVGGFALAFAKGWLLTLVMLTSIPFLAMAGAAM 208
Query: 2587 MQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHA 2766
+ R +A V Q + IRTV S ++Q +Y +Y+ + ++++
Sbjct: 209 ALLVTRASSRGQAAYAKAATVVEQTIGSIRTVASFTGEKQAINSYKKYITSAYKSSIQQG 268
Query: 2767 HTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFI 2946
+ G + F YA A + G + ++ V V + +G T+ +
Sbjct: 269 FSTGLGLGVMIYVFFSSYALAIWFGGKMILEKGYTGGSVINVIIIVVAGSMSLGQTSPCV 328
Query: 2947 PDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTKVLQG 3123
+ AA +F I+ ID+ +G ++ I G+I +++V F+YP R D ++ G
Sbjct: 329 TAFAAGQAAAYKMFETIKRKPLIDAYDVNGKVLGDIRGDIELKDVHFSYPARPDEEIFDG 388
Query: 3124 FTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCI 3303
F+L I +G T ALVG SG GKST++ L+ERFY+ G ++IDG N++ + +R ++ +
Sbjct: 389 FSLFIPSGATAALVGESGSGKSTVINLIERFYDPKAGEVLIDGINLKEFQLKWIRSKIGL 448
Query: 3304 VSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQL 3483
V QEP LF +I ENI YG N T QEI A ++AN FI LP G DT VGE GTQL
Sbjct: 449 VCQEPVLFSSSIMENIAYG-KENATLQEIKVATELANAAKFINNLPQGLDTKVGEHGTQL 507
Query: 3484 SGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLST 3663
SGGQKQRIAIARA+++ P VLLLDEATSALDTESE++VQEALD RT +V+AHRLST
Sbjct: 508 SGGQKQRIAIARAILKDPRVLLLDEATSALDTESERVVQEALDRVMVNRTTVVVAHRLST 567
Query: 3664 IQNSDVIAIVSEGKIVEKGTHDELIRKS 3747
++N+D+IA++ GK+VEKG+H EL++ S
Sbjct: 568 VRNADMIAVIHSGKMVEKGSHSELLKDS 595
>gi|39587992|emb|CAE57223.1| Hypothetical protein CBG00086
[Caenorhabditis briggsae]
Length = 1316
Score = 796 bits (2056), Expect = 0.0
Identities = 462/1247 (37%), Positives = 695/1247 (55%), Gaps = 33/1247 (2%)
Frame = +1
Query: 97 LTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDN 276
+T G+F + + D ++L+ G + + + G P L ++ GGMT +
Sbjct: 76 VTLLGLFRFAERRDHIILLIGILLSFLSGVAQPGLGVIAGGMTNTLI------------- 122
Query: 277 VNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLK 456
+ ++ +F + + +GV++ +++Q CF++ R+V KLR+ Y+K
Sbjct: 123 -----VYNVTSPQFLDSALMNVYLFGGIGVVVLIINFIQYMCFQNVCIRIVTKLREEYIK 177
Query: 457 AILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWS 636
+ILRQ WFDK +G LT +L D++ER+ EG+GDK +L++ F G + FY W
Sbjct: 178 SILRQNAGWFDKNHSGTLTTKLHDNMERIHEGIGDKLGVLIRGIVMFGTGIVISLFYEWR 237
Query: 637 MTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRE 816
+ L+MMG PL + + MS+SM++ T E AG+IAEE+ +RTV + NG +
Sbjct: 238 LALMMMGIGPLCCICMSLMSRSMSSYTSKELADVGKAGSIAEESLMGVRTVQAFNGQEEM 297
Query: 817 LDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIF 996
+ R+ L G+ + K + G G L +++ + +YG L+ + G +F
Sbjct: 298 VGRYTAELGKGKSYAVKKGLWGGFFGGIFLLILFTYFGGGIFYGGQLLRWKIIENPGDVF 357
Query: 997 TVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDI 1176
V F++L G+ LG PHL AR AA+T+ VI+ P+ID YS EG +D + G +
Sbjct: 358 IVVFSMLIGAYFLGLISPHLMVLLNARVAAATIYEVIDRVPEIDAYSNEGQKIDKIVGRV 417
Query: 1177 SFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVL 1356
F++VHFRYP+RK VL G++L ++ G +ALVG SGCGKST V LL R Y+ G+V+
Sbjct: 418 VFENVHFRYPTRKKAKVLNGLNLTIEPGTSVALVGHSGCGKSTSVGLLTRLYEQEDGKVM 477
Query: 1357 IDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDF 1536
IDG ++R +N+ LR+ +GIV QEP+LF GTI+ N+ +GN +AT D ++ CKMANA++F
Sbjct: 478 IDGHEVRNLNIDWLRKVVGIVQQEPILFSGTIHNNLLIGNPNATRDDMIRVCKMANAHEF 537
Query: 1537 IKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGA 1716
I ++P GY T +G+ GVQLSGGQKQR+AIAR L+++PK+LLLDEATSALD ++E VQ A
Sbjct: 538 ILKMPKGYDTVIGDGGVQLSGGQKQRVAIARTLIRDPKVLLLDEATSALDAQSESVVQSA 597
Query: 1717 LDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXX 1896
L+ A GRTTI++AHRLSTIR D+I F++G IVESG+H+EL++ G Y
Sbjct: 598 LNNASKGRTTIMIAHRLSTIREADKIVFFESGVIVESGTHDELVALGG-RYAALVKAQQF 656
Query: 1897 XXXXEAGKDIEDTISE-------------SAHSHLXXXXXXXXXXXXXXXIH-------- 2013
E D+E+ I+ S H +
Sbjct: 657 KEADEVDDDVEEDITARIFSEKQMPSRQVSYHGSCVSLASADLEIGYASAFNSFNLKQAQ 716
Query: 2014 ------QLAEEV----EECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALV 2163
AEEV EE + + IFK + S + A++
Sbjct: 717 DDIENEDFAEEVQRVMEEDGVITSGYYDIFKNAKGNYWYLSMGTVFAIMRGSELALLAIM 776
Query: 2164 YAEIFNVYSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAF 2343
+ +F + P +M + ++ +G+ F+ S+ E+L +K R ++F
Sbjct: 777 FGYVFEAFEKPDAEMARELVIIFILYGCLGLYVFITQVLSSTLFTIVAENLGLKFRVQSF 836
Query: 2344 KNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVF-TRLPVVLASIVTICGALGIGFYY 2520
KNLL QD +F+D+ H GKL TR ATDAPNV+ V TR+ V+ S+ +I L G+
Sbjct: 837 KNLLYQDASFFDNPAHAPGKLITRLATDAPNVKAVVDTRMLQVIYSMTSITINLVTGYAC 896
Query: 2521 GWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQ 2700
WQ + M + + +EAGK+A + VE+++T+ L
Sbjct: 897 CWQIAVVGTVMIALFAL-LMISMAYKIARVNLKQIKRDEAGKIAIEIVENVKTIQLLTST 955
Query: 2701 EQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPID 2880
E F Y L + +K A+ A SQ+ ++F + +G+ + + P
Sbjct: 956 EHFLTEYTTALELQHKSEMKKAYIQALNNAISQTFMYFAMFVCYAVGTPLMYNGIVDPNG 1015
Query: 2881 VYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLI-EHPTPIDSLSDSGIVKPITG 3057
+R ++ + +++ P+ VKA+ AA +LF LI P D + + + I G
Sbjct: 1016 AFRAINSMMMGSVAVMHSSHNFPEFVKAKTAAGMLFKLIYRKPKTGDVMKGNQL--DIRG 1073
Query: 3058 NISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGM 3237
NI +V F+YP R V+ + G+TVALVG SG GKST + +LERFY+ G
Sbjct: 1074 NILFESVKFSYPQRPLHPVMTDLHFTARNGQTVALVGPSGTGKSTCIAMLERFYDVSGGA 1133
Query: 3238 IMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANI 3417
+ IDG +I+ L++ LR Q+ +V QEP LF TI EN+C+G ++V +++ +A ++AN
Sbjct: 1134 LRIDGQDIKTLSLHHLRTQMALVGQEPRLFAGTIRENVCFGL-KDVPIEKVNQALELANA 1192
Query: 3418 HNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIV 3597
F+ LP G DT VGEKG+QLSGGQKQRIAIARALVR P +LLLDEATSALD+ESE+++
Sbjct: 1193 SRFLANLPSGIDTEVGEKGSQLSGGQKQRIAIARALVRDPKILLLDEATSALDSESERVM 1252
Query: 3598 QEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELI 3738
QEALD A++GRTC+ IAHRLS+IQNSD+I + +GK+ E G H+ L+
Sbjct: 1253 QEALDRAREGRTCITIAHRLSSIQNSDLIVYIDQGKVQEAGNHNHLM 1299
Score = 328 bits (840), Expect = 8e-88
Identities = 207/545 (37%), Positives = 299/545 (53%), Gaps = 5/545 (0%)
Frame = +1
Query: 2173 IFNVYSLP-ADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKN 2349
++NV S D NVY + G+ V++ I F+ + N R + KLR E K+
Sbjct: 123 VYNVTSPQFLDSALMNVYLFGGIGVVVLIINFIQYMCFQNVCIR----IVTKLREEYIKS 178
Query: 2350 LLRQDIAFYDDLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIVTICGALGIGFYYGW 2526
+LRQ+ ++D ++ +G L T+ + + + +L V++ IV + I +Y W
Sbjct: 179 ILRQNAGWFD--KNHSGTLTTKLHDNMERIHEGIGDKLGVLIRGIVMFGTGIVISLFYEW 236
Query: 2527 QXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQ 2706
+ + + ++ + +AG +A +++ +RTV + N QE+
Sbjct: 237 RLALMMMGIGPLCCICMSLMSRSMSSYTSKELADVGKAGSIAEESLMGVRTVQAFNGQEE 296
Query: 2707 FHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMY--AAAFYLGSIFVNQQAMQPID 2880
Y L + + +K +G F LI F Y FY G + + P D
Sbjct: 297 MVGRYTAELGKGKSYAVKKG-LWGGFFGGIFLLILFTYFGGGIFYGGQLLRWKIIENPGD 355
Query: 2881 VYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGI-VKPITG 3057
V+ V F++ +G + + ++ AR+AA+ ++ +I+ ID+ S+ G + I G
Sbjct: 356 VFIVVFSMLIGAYFLGLISPHLMVLLNARVAAATIYEVIDRVPEIDAYSNEGQKIDKIVG 415
Query: 3058 NISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGM 3237
+ NV F YPTRK KVL G L I+ G +VALVGHSGCGKST +GLL R Y Q+ G
Sbjct: 416 RVVFENVHFRYPTRKKAKVLNGLNLTIEPGTSVALVGHSGCGKSTSVGLLTRLYEQEDGK 475
Query: 3238 IMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANI 3417
+MIDG +RNLNI LR+ V IV QEP LF TI N+ G N N T +++ KMAN
Sbjct: 476 VMIDGHEVRNLNIDWLRKVVGIVQQEPILFSGTIHNNLLIG-NPNATRDDMIRVCKMANA 534
Query: 3418 HNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIV 3597
H FIL +P GYDT +G+ G QLSGGQKQR+AIAR L+R P VLLLDEATSALD +SE +V
Sbjct: 535 HEFILKMPKGYDTVIGDGGVQLSGGQKQRVAIARTLIRDPKVLLLDEATSALDAQSESVV 594
Query: 3598 QEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
Q AL+ A +GRT ++IAHRLSTI+ +D I G IVE GTHDEL+ Y + Q
Sbjct: 595 QSALNNASKGRTTIMIAHRLSTIREADKIVFFESGVIVESGTHDELVALGGRYAALVKAQ 654
Query: 3778 RIVES 3792
+ E+
Sbjct: 655 QFKEA 659
Score = 306 bits (784), Expect = 2e-81
Identities = 206/592 (34%), Positives = 309/592 (51%), Gaps = 2/592 (0%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNP 285
Y IF +G + L GTV A++ G+ LLAI+ G + F + P
Sbjct: 743 YDIFKNAKG-NYWYLSMGTVFAIMRGSELALLAIMFGYVFEAFEK--------------P 787
Query: 286 EGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAIL 465
+ E E+V I Y LG+ +F T + F AE L K R K +L
Sbjct: 788 DA-------EMARELVIIFILYGCLGLYVFITQVLSSTLFTIVAENLGLKFRVQSFKNLL 840
Query: 466 RQQIQWFDK--QQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSM 639
Q +FD G L RL D V+ + + ++ + G+ W +
Sbjct: 841 YQDASFFDNPAHAPGKLITRLATDAPNVKAVVDTRMLQVIYSMTSITINLVTGYACCWQI 900
Query: 640 TLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKREL 819
+V L L M+ +A R ++Q AG IA E +++T+ L + L
Sbjct: 901 AVVGTVMIALFALLMISMAYKIA-RVNLKQIKRDEAGKIAIEIVENVKTIQLLTSTEHFL 959
Query: 820 DRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFT 999
+ ALE+ ++ + K + S MY + + + G+ L+ N G F
Sbjct: 960 TEYTTALELQHKSEMKKAYIQALNNAISQTFMYFAMFVCYAVGTPLMYNGIVDPNGA-FR 1018
Query: 1000 VFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDIS 1179
+++ GS ++ + + F A+ AA + ++I PK ++G +D ++G+I
Sbjct: 1019 AINSMMMGSVAVMHSSHNFPEFVKAKTAAGMLFKLIYRKPKTGDV-MKGNQLD-IRGNIL 1076
Query: 1180 FKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLI 1359
F+ V F YP R V+ + + G +ALVG SG GKST + +L+RFYD + G + I
Sbjct: 1077 FESVKFSYPQRPLHPVMTDLHFTARNGQTVALVGPSGTGKSTCIAMLERFYDVSGGALRI 1136
Query: 1360 DGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFI 1539
DG D++ +++H LR Q+ +V QEP LF GTI EN+ G + ++V +A ++ANA+ F+
Sbjct: 1137 DGQDIKTLSLHHLRTQMALVGQEPRLFAGTIRENVCFGLKDVPIEKVNQALELANASRFL 1196
Query: 1540 KRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGAL 1719
LP G T VGEKG QLSGGQKQRIAIARALV++PKILLLDEATSALD+E+ER +Q AL
Sbjct: 1197 ANLPSGIDTEVGEKGSQLSGGQKQRIAIARALVRDPKILLLDEATSALDSESERVMQEAL 1256
Query: 1720 DQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM 1875
D+A+ GRT I +AHRLS+I+N D I G + E+G+H LMS +G +YD+
Sbjct: 1257 DRAREGRTCITIAHRLSSIQNSDLIVYIDQGKVQEAGNHNHLMSLRGKYYDL 1308
>gi|157873|gb|AAA16186.1| P-glycoprotein/multidrug resistance protein
Length = 1283
Score = 796 bits (2055), Expect = 0.0
Identities = 460/1243 (37%), Positives = 702/1243 (56%), Gaps = 15/1243 (1%)
Frame = +1
Query: 94 KLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVD 273
+++ + +F Y D L + G ++AV G P +++ G + + G
Sbjct: 43 QVSYFQLFRYATKKDRALYVIGLLSAVGTGLTTPANSLIFGNLANDMIDLSGL-LESGKS 101
Query: 274 NVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYL 453
+ + + LD+ V ++ + +G++M SY+ I CF A + +R +
Sbjct: 102 YRADDAISTLLLDK----VRQFSLQNTYIGMIMLVCSYLSITCFNYAAHSQILTIRSKFF 157
Query: 454 KAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSW 633
++IL Q ++W+D Q+G + +R+ +DL ++ +GL +K + V AF+ + F W
Sbjct: 158 RSILHQDMKWYDFNQSGEVASRMNEDLSKMEDGLAEKVVMFVHYLVAFVGSLVLAFVKGW 217
Query: 634 SMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKR 813
++LV + PL ++ ++ + + + E YA A +AE S IRTV + G +
Sbjct: 218 QLSLVCLTSLPLTFIAMGLVAVATSRLAKKEVTMYAGAAVVAEGALSGIRTVKAFEGEAK 277
Query: 814 ELDRFYNALEVGRQTGIVKYCYMGIGVGFS-NLCMYSSYALAFWYGSTLIINDP--TFDR 984
E+ + + + I + + GIG G +Y+SYALAFWYG L+I +D
Sbjct: 278 EVAAYKERVVAAKILNIKRNMFSGIGFGLLWFFFIYASYALAFWYGVGLVIESAYENYDA 337
Query: 985 GLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNM 1164
G + TVFF+V+ GS ++G A P++ +FG A+G V +I P+I+P + + V+
Sbjct: 338 GTMITVFFSVMMGSMNIGMAAPYIEAFGIAQGRLPKVFHIIEQIPEINPL-MGRVKVNEP 396
Query: 1165 KGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTK 1344
I FK+V F+YP+R ++ +L ++L++ G +ALVG SGCGKST + L+QRFYDP
Sbjct: 397 LTTIEFKEVEFQYPTRPEVSILNKLNLKIHRGQTVALVGPSGCGKSTCIQLVQRFYDPQA 456
Query: 1345 GRVLIDGVDLREVNVHSLRE-QIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMA 1521
G +L +G +L++++++ LR +IG+V QEP+LF +IYENI+ G E AT +++ A A
Sbjct: 457 GNLLFNGTNLKDLDINWLRFLRIGVVGQEPILFATSIYENIRYGREDATREEIEAARAAA 516
Query: 1522 NANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAER 1701
NA FIK+LP GY T VGE+G QLSGGQKQRIAI RAL+++P+ILLLDEATSALDT +E
Sbjct: 517 NAAIFIKKLPKGYDTLVGERGAQLSGGQKQRIAIRRALIRDPEILLLDEATSALDTASEA 576
Query: 1702 EVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM-- 1875
+VQ AL++ AGRTTIIVAHRLST+R DRI V G +VESG+H+ELM + ++++
Sbjct: 577 KVQAALEKVSAGRTTIIVAHRLSTVRRADRIVVINKGEVVESGTHQELMELKDHYFNLVT 636
Query: 1876 TXXXXXXXXXXEAGKDIEDT--ISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKAP 2049
T DI I + + +++++ K P
Sbjct: 637 TQLGEDDGSVLSPTGDIYKNFDIKDEDEEEIKVLSEDEDEDVMVTDEKNKKKKMKKVKDP 696
Query: 2050 --PTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQ--MQAN 2217
M ++ K N + P+FA+++ I + S+ + ++ N
Sbjct: 697 NEVKPMLEVMKMNKPEWLQIAVGCISSVIMGCAMPIFAVLFGSILQILSVKDNDQYVREN 756
Query: 2218 VYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGT 2397
+ F++ GI + F G GE LT +LR F+ +LRQ++A++DD +GT
Sbjct: 757 SNQYSLYFLIAGIVVGIATFLQIYFFGIAGERLTERLRGLMFEAMLRQEVAWFDDKANGT 816
Query: 2398 GKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMG 2574
G LC R + DA V+ R+ ++ SI T+ + + YY W +
Sbjct: 817 GSLCARLSGDAAAVQGATGQRIGTIIQSISTLALGIALSMYYEWSLGLVALAFTPFILIA 876
Query: 2575 GYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTN 2754
Y + + + +R + +E K+A + V +IRTV SL R+E FH Y L +
Sbjct: 877 FYMQRTLMAKENMRPAKTMENCTKLAVEVVSNIRTVASLGREEMFHQNYIGMLIPAVEIS 936
Query: 2755 LKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNT 2934
++ H G V+ ++SL+FF YAA Y G+ V + + DV++V A+ I N
Sbjct: 937 KRNTHFRGLVYGLARSLMFFAYAACMYYGTWCVIHRGILFGDVFKVSQAVIMGTASIANA 996
Query: 2935 TSFIPDVVKARLAASLLF-YLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTK 3111
+F P++ K AA +F +L P+ +D S G + V F+YPTR + +
Sbjct: 997 LAFAPNMQKGVSAAKTIFTFLRRQPSIVDRPGVSRDPWHSEGYVRFDKVKFSYPTRSEIQ 1056
Query: 3112 VLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLRE 3291
VL+G L + G+ +ALVG SGCGKST + L++RFY+ D+G +ID ++RN+++++LR
Sbjct: 1057 VLKGLELAVSKGQKIALVGPSGCGKSTCIQLIQRFYDVDEGATLIDECDVRNVSMTNLRN 1116
Query: 3292 QVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGE 3468
Q+ IVSQEP LFD TI ENI YG N RNVT QEI+ A K +NIH FI LP GYDT +GE
Sbjct: 1117 QLGIVSQEPILFDRTIRENISYGDNARNVTDQEIISACKKSNIHEFIANLPLGYDTRMGE 1176
Query: 3469 KGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIA 3648
KG QLSGGQKQRIAIARAL+R+P ++LLDEATSALD ESEK+VQ+ALDAA +GRT + IA
Sbjct: 1177 KGAQLSGGQKQRIAIARALIRNPKIMLLDEATSALDAESEKVVQDALDAASEGRTTISIA 1236
Query: 3649 HRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
HRLST+ +SDVI + G + E G H +L+ +Y + Q
Sbjct: 1237 HRLSTVVHSDVIFVFENGLVCEAGDHKQLLANRGLYYTLYKLQ 1279
>gi|1079107|pir||A47377 multidrug resistance protein Mdr50 - fruit fly
(Drosophila melanogaster)
Length = 1283
Score = 796 bits (2055), Expect = 0.0
Identities = 460/1243 (37%), Positives = 702/1243 (56%), Gaps = 15/1243 (1%)
Frame = +1
Query: 94 KLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVD 273
+++ + +F Y D L + G ++AV G P +++ G + + G
Sbjct: 43 QVSYFQLFRYATKKDRALYVIGLLSAVGTGLTTPANSLIFGNLANDMIDLSGL-LESGKS 101
Query: 274 NVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYL 453
+ + + LD+ V ++ + +G++M SY+ I CF A + +R +
Sbjct: 102 YRADDAISTLLLDK----VRQFSLQNTYIGMIMLVCSYLSITCFNYAAHSQILTIRSKFF 157
Query: 454 KAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSW 633
++IL Q ++W+D Q+G + +R+ +DL ++ +GL +K + V AF+ + F W
Sbjct: 158 RSILHQDMKWYDFNQSGEVASRMNEDLSKMEDGLAEKVVMFVHYLVAFVGSLVLAFVKGW 217
Query: 634 SMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKR 813
++LV + PL ++ ++ + + + E YA A +AE S IRTV + G +
Sbjct: 218 QLSLVCLTSLPLTFIAMGLVAVATSRLAKKEVTMYAGAAVVAEGALSGIRTVKAFEGEAK 277
Query: 814 ELDRFYNALEVGRQTGIVKYCYMGIGVGFS-NLCMYSSYALAFWYGSTLIINDP--TFDR 984
E+ + + + I + + GIG G +Y+SYALAFWYG L+I +D
Sbjct: 278 EVAAYKERVVAAKILNIKRNMFSGIGFGLLWFFFIYASYALAFWYGVGLVIESAYENYDA 337
Query: 985 GLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNM 1164
G + TVFF+V+ GS ++G A P++ +FG A+G V +I P+I+P + + V+
Sbjct: 338 GTMITVFFSVMMGSMNIGMAAPYIEAFGIAQGRLPKVFHIIEQIPEINPL-MGRVKVNEP 396
Query: 1165 KGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTK 1344
I FK+V F+YP+R ++ +L ++L++ G +ALVG SGCGKST + L+QRFYDP
Sbjct: 397 LTTIEFKEVEFQYPTRPEVSILNKLNLKIHRGQTVALVGPSGCGKSTCIQLVQRFYDPQA 456
Query: 1345 GRVLIDGVDLREVNVHSLRE-QIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMA 1521
G +L +G +L++++++ LR +IG+V QEP+LF +IYENI+ G E AT +++ A A
Sbjct: 457 GNLLFNGTNLKDLDINWLRFLRIGVVGQEPILFATSIYENIRYGREDATREEIEAARAAA 516
Query: 1522 NANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAER 1701
NA FIK+LP GY T VGE+G QLSGGQKQRIAI RAL+++P+ILLLDEATSALDT +E
Sbjct: 517 NAAIFIKKLPKGYDTLVGERGAQLSGGQKQRIAIRRALIRDPEILLLDEATSALDTASEA 576
Query: 1702 EVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM-- 1875
+VQ AL++ AGRTTIIVAHRLST+R DRI V G +VESG+H+ELM + ++++
Sbjct: 577 KVQAALEKVSAGRTTIIVAHRLSTVRRADRIVVINKGEVVESGTHQELMELKDHYFNLVT 636
Query: 1876 TXXXXXXXXXXEAGKDIEDT--ISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKAP 2049
T DI I + + +++++ K P
Sbjct: 637 TQLGEDDGSVLSPTGDIYKNFDIKDEDEEEIKVLSEDEDEDVMVTDEKNKKKKMKKVKDP 696
Query: 2050 --PTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQ--MQAN 2217
M ++ K N + P+FA+++ I + S+ + ++ N
Sbjct: 697 NEVKPMLEVMKMNKPEWLQIAVGCISSVIMGCAMPIFAVLFGSILQILSVKDNDQYVREN 756
Query: 2218 VYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGT 2397
+ F++ GI + F G GE LT +LR F+ +LRQ++A++DD +GT
Sbjct: 757 SNQYSLYFLIAGIVVGIATFLQIYFFGIAGERLTERLRGLMFEAMLRQEVAWFDDKANGT 816
Query: 2398 GKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMG 2574
G LC R + DA V+ R+ ++ SI T+ + + YY W +
Sbjct: 817 GSLCARLSGDAAAVQGATGQRIGTIIQSISTLALGIALSMYYEWSLGLVALAFTPFILIA 876
Query: 2575 GYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTN 2754
Y + + + +R + +E K+A + V +IRTV SL R+E FH Y L +
Sbjct: 877 FYMQRTLMAKENMRPAKTMENCTKLAVEVVSNIRTVASLGREEMFHQNYIGMLIPAVEIS 936
Query: 2755 LKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNT 2934
++ H G V+ ++SL+FF YAA Y G+ V + + DV++V A+ I N
Sbjct: 937 KRNTHFRGLVYGLARSLMFFAYAACMYYGTWCVIHRGILFGDVFKVSQAVIMGTASIANA 996
Query: 2935 TSFIPDVVKARLAASLLF-YLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTK 3111
+F P++ K AA +F +L P+ +D S G + V F+YPTR + +
Sbjct: 997 LAFAPNMQKGVSAAKTIFTFLRRQPSIVDRPGVSRDPWHSEGYVRFDKVKFSYPTRSEIQ 1056
Query: 3112 VLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLRE 3291
VL+G L + G+ +ALVG SGCGKST + L++RFY+ D+G +ID ++RN+++++LR
Sbjct: 1057 VLKGLELAVSKGQKIALVGPSGCGKSTCIQLIQRFYDVDEGATLIDECDVRNVSMTNLRN 1116
Query: 3292 QVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGE 3468
Q+ IVSQEP LFD TI ENI YG N RNVT QEI+ A K +NIH FI LP GYDT +GE
Sbjct: 1117 QLGIVSQEPILFDRTIRENISYGDNARNVTDQEIISACKKSNIHEFIANLPLGYDTRMGE 1176
Query: 3469 KGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIA 3648
KG QLSGGQKQRIAIARAL+R+P ++LLDEATSALD ESEK+VQ+ALDAA +GRT + IA
Sbjct: 1177 KGAQLSGGQKQRIAIARALIRNPKIMLLDEATSALDAESEKVVQDALDAASEGRTTISIA 1236
Query: 3649 HRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
HRLST+ +SDVI + G + E G H +L+ +Y + Q
Sbjct: 1237 HRLSTVVHSDVIFVFENGLVCEAGDHKQLLANRGLYYTLYKLQ 1279
>gi|15237456|ref|NP_199466.1| ABC transporter family protein
[Arabidopsis thaliana]
Length = 1248
Score = 795 bits (2053), Expect = 0.0
Identities = 451/1238 (36%), Positives = 694/1238 (55%), Gaps = 20/1238 (1%)
Frame = +1
Query: 94 KLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVD 273
++ Y +F + D++L++ GT++A+ +G P ++I++G + VF + +
Sbjct: 17 RIAFYKLFTFADRYDIVLMVIGTLSAMANGLTQPFMSILMGQLINVFGFSDH-------- 68
Query: 274 NVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYL 453
D EV K + +L L S++Q++C+ ER ++R+ YL
Sbjct: 69 ------------DHVFKEVSKVAVKFLYLAAYAGVVSFLQVSCWMVTGERQSTRIRRLYL 116
Query: 454 KAILRQQIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYS 630
K ILRQ I +FD + TG + R++ D +++ +G+K Q+ ++F+ G+ V F
Sbjct: 117 KTILRQDIGFFDTETNTGEVIGRMSGDTILIQDSMGEKVGKFTQLVSSFVGGFTVAFIVG 176
Query: 631 WSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHK 810
+TL ++ PLIV +G M+ M+ + + Q Y AG + ++ SIRTV + G K
Sbjct: 177 MKLTLALLPCVPLIVGTGGAMTYIMSKKAQRVQLAYTEAGNVVQQAVGSIRTVVAFTGEK 236
Query: 811 RELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGL 990
+ + ++ LE+ ++ + + Y G+G+G + +Y +Y A WYG+ II + + G
Sbjct: 237 QSMGKYEKKLEIAYKSMVKQGLYSGLGIGIMMVVVYCTYGFAIWYGARQII-EKGYTGGQ 295
Query: 991 IFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKG 1170
+ V ++L+G +LG LP L SF AA + I PKID Y + G +++ +KG
Sbjct: 296 VMNVITSILTGGMALGQTLPSLNSFAAGTAAAYKMFETIKRKPKIDAYDMSGEVLEEIKG 355
Query: 1171 DISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGR 1350
DI +DV+FRYP+R D+ + G SL + G +ALVG SG GKST+++L++RFYDP G
Sbjct: 356 DIELRDVYFRYPARPDVQIFVGFSLTVPNGMTVALVGQSGSGKSTVISLIERFYDPESGE 415
Query: 1351 VLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAN 1530
VLIDG+DL++ V +R +IG+VSQEP+LF TI ENI G + A+ ++ A K+ANA+
Sbjct: 416 VLIDGIDLKKFQVKWIRSKIGLVSQEPILFATTIRENIVYGKKDASDQEIRTALKLANAS 475
Query: 1531 DFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQ 1710
+FI +LP G T VGE G QLSGGQKQRIAIARA++KNPKILLLDEATSALD E+ER VQ
Sbjct: 476 NFIDKLPQGLETMVGEHGTQLSGGQKQRIAIARAILKNPKILLLDEATSALDAESERIVQ 535
Query: 1711 GALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXX 1890
AL + RTT++VAHRL+TIR D I V + G ++E G+H+E++ Y
Sbjct: 536 DALVKLMLSRTTVVVAHRLTTIRTADMIAVVQQGKVIEKGTHDEMIKDPEGTYSQLVRLQ 595
Query: 1891 XXXXXXEA----------GKDIEDTISESA-HSHLXXXXXXXXXXXXXXXIHQLAEEVEE 2037
EA +IE + S++ HS + E +
Sbjct: 596 EGSKKEEAIDKEPEKCEMSLEIESSDSQNGIHSGTLTSPSGLPGVISLDQTEEFHENISS 655
Query: 2038 C------KAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPA 2199
K S+ ++ N ++ V PV L+ + ++ P+
Sbjct: 656 TKTQTVKKGKEVSLRRLAHLNKPEISVLLLGSLAAVIHGIVFPVQGLLLSRTIRIFFEPS 715
Query: 2200 DQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYD 2379
++++ + FW +FV +G+T + G L ++R +F +L QDI+++D
Sbjct: 716 NKLKNDSLFWALIFVALGLTDLIVIPLQNYLFAIAGAKLIKRIRSLSFDRVLHQDISWFD 775
Query: 2380 DLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXX 2556
D ++ +G + R +TDA V+ V L +++ ++ TI GA I F W
Sbjct: 776 DTKNSSGVIGARLSTDASTVKSIVGDVLGLIMQNMATIIGAFIIAFTANWLLALMALLVA 835
Query: 2557 XXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLR 2736
GY++++ G + EEA +VAS AV IRTV S +++ Y E
Sbjct: 836 PVMFFQGYYQIKFITGFGAKARGKYEEASQVASDAVSSIRTVASFCAEDKVMDLYQEKCD 895
Query: 2737 EPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCG 2916
EP K G + S ++ + + F GS + + + ++VFFA++
Sbjct: 896 EPKQQGFKLGLVSGLCYGGSYLALYVIESVCFLGGSWLIQNRRATFGEFFQVFFALTLTA 955
Query: 2917 QMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPIT-GNISIRNVFFNYP 3093
+ T++ PD+ KA+ +A+ +F +++ IDS S+ G + PI G+I +++V F YP
Sbjct: 956 VGVTQTSTMAPDINKAKDSAASIFDILDSKPKIDSSSEKGTILPIVHGDIELQHVSFRYP 1015
Query: 3094 TRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLN 3273
R D ++ L I +G+TVALVG SG GKST++ LLERFY+ D G I++D I++L
Sbjct: 1016 MRPDIQIFSDLCLTISSGQTVALVGESGSGKSTVISLLERFYDPDSGKILLDQVEIQSLK 1075
Query: 3274 ISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYD 3453
+S LREQ+ +VSQEP LF+ TIG NI YG T +EI+ AAK AN+HNFI LP GY+
Sbjct: 1076 LSWLREQMGLVSQEPVLFNETIGSNIAYGKIGGATEEEIITAAKAANVHNFISSLPQGYE 1135
Query: 3454 THVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRT 3633
T VGE+G QLSGGQKQRIAIARA+++ P +LLLDEATSALD ESE++VQ+ALD RT
Sbjct: 1136 TSVGERGVQLSGGQKQRIAIARAILKDPKILLLDEATSALDAESERVVQDALDQVMVNRT 1195
Query: 3634 CLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKS 3747
+V+AH L+TI+++D+IA+V G I E G H+ L+ S
Sbjct: 1196 TVVVAHLLTTIKDADMIAVVKNGVIAESGRHETLMEIS 1233
Score = 369 bits (948), Expect = e-100
Identities = 218/582 (37%), Positives = 324/582 (55%), Gaps = 4/582 (0%)
Frame = +1
Query: 136 DLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDE 315
++ +L+ G++AAVIHG FP+ ++L +F N +
Sbjct: 679 EISVLLLGSLAAVIHGIVFPVQGLLLSRTIRIFFEPSN---------------------K 717
Query: 316 FNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD-- 489
++ + + + ++ LG+ +Q F +L+ ++R +L Q I WFD
Sbjct: 718 LKNDSLFWALIFVALGLTDLIVIPLQNYLFAIAGAKLIKRIRSLSFDRVLHQDISWFDDT 777
Query: 490 KQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPL 669
K +G + ARL+ D V+ +GD L++Q A + + + F +W + L+ + AP+
Sbjct: 778 KNSSGVIGARLSTDASTVKSIVGDVLGLIMQNMATIIGAFIIAFTANWLLALMALLVAPV 837
Query: 670 IVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVG 849
+ G K + + Y A +A + SSIRTV S + +D + +
Sbjct: 838 MFFQGYYQIKFITGFGAKARGKYEEASQVASDAVSSIRTVASFCAEDKVMDLYQEKCDEP 897
Query: 850 RQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIIND-PTFDRGLIFTVFFAVLSGS 1026
+Q G G+ G S L +Y ++ F GS LI N TF G F VFFA+ +
Sbjct: 898 KQQGFKLGLVSGLCYGGSYLALYVIESVCFLGGSWLIQNRRATF--GEFFQVFFALTLTA 955
Query: 1027 TSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYP 1206
+ A+ +A+++ +++S PKID S +G ++ + GDI + V FRYP
Sbjct: 956 VGVTQTSTMAPDINKAKDSAASIFDILDSKPKIDSSSEKGTILPIVHGDIELQHVSFRYP 1015
Query: 1207 SRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVN 1386
R DI + + L + +G +ALVG SG GKST+++LL+RFYDP G++L+D V+++ +
Sbjct: 1016 MRPDIQIFSDLCLTISSGQTVALVGESGSGKSTVISLLERFYDPDSGKILLDQVEIQSLK 1075
Query: 1387 VHSLREQIGIVSQEPVLFDGTIYENIKMGN-EHATHDQVVEACKMANANDFIKRLPDGYG 1563
+ LREQ+G+VSQEPVLF+ TI NI G AT ++++ A K AN ++FI LP GY
Sbjct: 1076 LSWLREQMGLVSQEPVLFNETIGSNIAYGKIGGATEEEIITAAKAANVHNFISSLPQGYE 1135
Query: 1564 TRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRT 1743
T VGE+GVQLSGGQKQRIAIARA++K+PKILLLDEATSALD E+ER VQ ALDQ RT
Sbjct: 1136 TSVGERGVQLSGGQKQRIAIARAILKDPKILLLDEATSALDAESERVVQDALDQVMVNRT 1195
Query: 1744 TIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFY 1869
T++VAH L+TI++ D I V K G I ESG HE LM G Y
Sbjct: 1196 TVVVAHLLTTIKDADMIAVVKNGVIAESGRHETLMEISGGAY 1237
Score = 305 bits (781), Expect = 5e-81
Identities = 194/539 (35%), Positives = 292/539 (53%), Gaps = 4/539 (0%)
Frame = +1
Query: 2146 PVFALVYAEIFNVYSLPA-DQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTM 2322
P +++ ++ NV+ D + V F+ + V F +C GE +
Sbjct: 50 PFMSILMGQLINVFGFSDHDHVFKEVSKVAVKFLYLAAYAGVVSFLQVSCWMVTGERQST 109
Query: 2323 KLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVFTRLPVVLASIVT-ICGA 2499
++R K +LRQDI F+D TG++ R + D ++ +V+ G
Sbjct: 110 RIRRLYLKTILRQDIGFFDT-ETNTGEVIGRMSGDTILIQDSMGEKVGKFTQLVSSFVGG 168
Query: 2500 LGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLL-EEAGKVASQAVEHIR 2676
+ F G + +G M K+ + QL EAG V QAV IR
Sbjct: 169 FTVAFIVGMKLTLALLPCVPLI-VGTGGAMTYIMSKKAQRVQLAYTEAGNVVQQAVGSIR 227
Query: 2677 TVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVN 2856
TV + ++Q Y + L + + +K G +++ Y A + G+ +
Sbjct: 228 TVVAFTGEKQSMGKYEKKLEIAYKSMVKQGLYSGLGIGIMMVVVYCTYGFAIWYGARQII 287
Query: 2857 QQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSG 3036
++ V V +I G +G T + AA +F I+ ID+ SG
Sbjct: 288 EKGYTGGQVMNVITSILTGGMALGQTLPSLNSFAAGTAAAYKMFETIKRKPKIDAYDMSG 347
Query: 3037 -IVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLER 3213
+++ I G+I +R+V+F YP R D ++ GF+L + G TVALVG SG GKST++ L+ER
Sbjct: 348 EVLEEIKGDIELRDVYFRYPARPDVQIFVGFSLTVPNGMTVALVGQSGSGKSTVISLIER 407
Query: 3214 FYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIV 3393
FY+ + G ++IDG +++ + +R ++ +VSQEP LF TI ENI YG ++ + QEI
Sbjct: 408 FYDPESGEVLIDGIDLKKFQVKWIRSKIGLVSQEPILFATTIRENIVYG-KKDASDQEIR 466
Query: 3394 EAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSAL 3573
A K+AN NFI LP G +T VGE GTQLSGGQKQRIAIARA++++P +LLLDEATSAL
Sbjct: 467 TALKLANASNFIDKLPQGLETMVGEHGTQLSGGQKQRIAIARAILKNPKILLLDEATSAL 526
Query: 3574 DTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSE 3750
D ESE+IVQ+AL RT +V+AHRL+TI+ +D+IA+V +GK++EKGTHDE+I+ E
Sbjct: 527 DAESERIVQDALVKLMLSRTTVVVAHRLTTIRTADMIAVVQQGKVIEKGTHDEMIKDPE 585
>gi|34911450|ref|NP_917072.1| putative multidrug resistance protein 1
homolog [Oryza sativa (japonica cultivar-group)]
gi|22535536|dbj|BAC10713.1| putative multidrug resistance protein 1
homolog [Oryza sativa (japonica cultivar-group)]
Length = 1265
Score = 794 bits (2051), Expect = 0.0
Identities = 465/1246 (37%), Positives = 707/1246 (56%), Gaps = 30/1246 (2%)
Frame = +1
Query: 94 KLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVD 273
KL G+F Y GVD L+ GTVAA+ +G PL+ +V + F G D
Sbjct: 29 KLPFLGMFRYADGVDKALMAVGTVAAMANGMSEPLMTVVFSAVIDCF----------GGD 78
Query: 274 NVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYL 453
+V+ ++ S+V+ + VL + +F Q++C+ ER +R YL
Sbjct: 79 DVS-------TVLHRVSKVLSH-----VLWLSLFVVVSNQVSCWTMAGERQSACIRSLYL 126
Query: 454 KAILRQQIQWFDKQQT-GNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYS 630
+AI+ Q I +FD + T G +R++ D +++ LG+K +Q+ AF+ G+ +GF
Sbjct: 127 EAIITQDIAFFDVEMTTGEAASRISADTVLIQDALGEKVGKYIQVLTAFVGGFVIGFIRG 186
Query: 631 WSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHK 810
W + LV+M P + S A +S+ A + +Y+ AG + E+T SIR V S NG K
Sbjct: 187 WMLALVVMACIPPSIFSFALVSRLRAQISGKTHVSYSYAGNVVEQTIGSIRMVVSFNGEK 246
Query: 811 RELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGL 990
R + + ++ + I++ G G+G +Y SY+LAFWYG+ L+I+ + G
Sbjct: 247 RAITMYNTLIKKAYKATIMEGIISGFGIGSIFFVVYCSYSLAFWYGAKLVISKG-YTGGQ 305
Query: 991 IFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKG 1170
+ V FA+L+GS ++G A P +++ + AA + +IN P ID GI+++++KG
Sbjct: 306 VINVVFAILTGSMAIGNASPSISAIAEGQSAAHRLFEIINRKPNIDITGTSGIILEDIKG 365
Query: 1171 DISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGR 1350
++ KDV F YP+R + +L G+ L++ G +A+VG SG GKSTI++L++RFYDP G
Sbjct: 366 NVELKDVCFSYPARPEQLILDGLCLQVPNGTTMAIVGQSGSGKSTIISLVERFYDPQDGE 425
Query: 1351 VLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAN 1530
VLIDG++++ + +H +R ++ +VSQEP+LF +I +NI G E+AT +++ A ++ANA
Sbjct: 426 VLIDGINIKTLKLHWIRGKMSLVSQEPLLFMTSIKDNITYGKENATDEEIKRAAELANAA 485
Query: 1531 DFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQ 1710
+FI +LP+ Y T VG+ G QLSGGQKQRIAIARA++KNPK+LLLDEATSALD E+ER VQ
Sbjct: 486 NFIDKLPNAYDTMVGQHGAQLSGGQKQRIAIARAILKNPKVLLLDEATSALDVESERLVQ 545
Query: 1711 GALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFY------- 1869
AL++ GRTT+IVAHRLSTI+N D I V G IV+ GSH+EL+ Y
Sbjct: 546 EALNRVMIGRTTLIVAHRLSTIKNADCIAVVHQGKIVDQGSHDELIKDPDGAYSQLIQLQ 605
Query: 1870 --------DMTXXXXXXXXXXEAGKDIEDT-ISESAHSHLXXXXXXXXXXXXXXXIHQ-- 2016
D+ +E + I++S + +H+
Sbjct: 606 QTHTEEMHDVQYSEVSTSRLKSRSLSLEQSMINDSPRNRRKNSLAKHIGSSGSDGLHKHG 665
Query: 2017 LAEEVE--EC-------KAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYA 2169
L +E E EC KAP + ++F N + + P+F+++ +
Sbjct: 666 LTDEPEDKECGDNKDINKAP---IRRLFNLNKPEAPILLLAIITAFVHGLLFPIFSIMMS 722
Query: 2170 EIFNVYSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKN 2349
+ P Q++ + FW M +LM I V G G L ++R +F++
Sbjct: 723 GGIRTFYYPPHQLRKDSRFWALMCILMAIISLVSIQLEYFLFGMAGGKLIERVRCLSFQS 782
Query: 2350 LLRQDIAFYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGW 2526
++ Q+++++DD H +G L + DA N+R V L +++ IVT+ I F W
Sbjct: 783 IVHQEVSWFDDPSHSSGSLGAKLYIDALNIRRLVGDNLAILVQCIVTLIAGFTIAFASDW 842
Query: 2527 QXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQ 2706
+ + Y +++ G + E+A +V ++A+ IRTV S +++
Sbjct: 843 KLTLTIMCPIPLVGLQNYVQLKFLKGFSEDAKVMYEDASQVVTEAIGSIRTVASFCAEKR 902
Query: 2707 FHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVY 2886
TY + + +++ G F+FS +++ YA FY+G+ FV+ DV+
Sbjct: 903 VIKTYNQKCQASMKESIRSGMVGGLGFSFSYLMVYLTYALCFYVGAQFVHGGKSTFKDVF 962
Query: 2887 RVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIV-KPITGNI 3063
RV+FA+ F I T++ D KA +A+ + +I+ + IDS D GI+ + + G I
Sbjct: 963 RVYFALVFTAFGISQTSAMASDSSKAHESAASILAIIDRKSNIDSSIDEGIILEKVNGTI 1022
Query: 3064 SIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIM 3243
+ +V F YP+R D +VL FTL I +GKTVALVG SG GKST++ LLERFY+ G I
Sbjct: 1023 ELNHVNFKYPSRPDVQVLCDFTLGIPSGKTVALVGESGSGKSTVIALLERFYDPHSGTIS 1082
Query: 3244 IDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHN 3423
+D ++NL +S LR+Q+ +VSQEP LF+ TI NI YG VT +EI+ AK +N H
Sbjct: 1083 LDRVELKNLKLSWLRDQMGLVSQEPILFNDTIHANIAYGRKGQVTEEEIIAVAKASNAHE 1142
Query: 3424 FILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQE 3603
FI LP GY+T VGE+GTQLSGGQKQRIAIARA+++ P +LLLDEATSALD ESE+IVQ+
Sbjct: 1143 FISSLPQGYNTTVGERGTQLSGGQKQRIAIARAILKDPKILLLDEATSALDAESERIVQD 1202
Query: 3604 ALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIR 3741
ALD RT +V+AHRLSTI+ +DVIA++ +G I EKG HD L+R
Sbjct: 1203 ALDQVMVSRTTIVVAHRLSTIKGADVIAVIKDGSIAEKGQHDSLMR 1248
Score = 363 bits (933), Expect = 1e-98
Identities = 205/578 (35%), Positives = 319/578 (54%), Gaps = 3/578 (0%)
Frame = +1
Query: 145 LLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNS 324
+L+ + A +HG FP+ +I++ G F + +
Sbjct: 699 ILLLAIITAFVHGLLFPIFSIMMSGGIRTFYYPPH---------------------QLRK 737
Query: 325 EVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD--KQQ 498
+ + + +++ ++ + ++ F +L+ ++R ++I+ Q++ WFD
Sbjct: 738 DSRFWALMCILMAIISLVSIQLEYFLFGMAGGKLIERVRCLSFQSIVHQEVSWFDDPSHS 797
Query: 499 TGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVL 678
+G+L A+L D +R +GD A+LVQ +AG+ + F W +TL +M PL+ L
Sbjct: 798 SGSLGAKLYIDALNIRRLVGDNLAILVQCIVTLIAGFTIAFASDWKLTLTIMCPIPLVGL 857
Query: 679 SGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQT 858
K + + + Y A + E SIRTV S KR + + + +
Sbjct: 858 QNYVQLKFLKGFSEDAKVMYEDASQVVTEAIGSIRTVASFCAEKRVIKTYNQKCQASMKE 917
Query: 859 GIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLG 1038
I G+G FS L +Y +YAL F+ G+ + + + +F V+FA++ + +
Sbjct: 918 SIRSGMVGGLGFSFSYLMVYLTYALCFYVGAQFVHGGKSTFKD-VFRVYFALVFTAFGIS 976
Query: 1039 GALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKD 1218
+ A +A+++L +I+ ID EGI+++ + G I V+F+YPSR D
Sbjct: 977 QTSAMASDSSKAHESAASILAIIDRKSNIDSSIDEGIILEKVNGTIELNHVNFKYPSRPD 1036
Query: 1219 IHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSL 1398
+ VL +L + +G +ALVG SG GKST++ LL+RFYDP G + +D V+L+ + + L
Sbjct: 1037 VQVLCDFTLGIPSGKTVALVGESGSGKSTVIALLERFYDPHSGTISLDRVELKNLKLSWL 1096
Query: 1399 REQIGIVSQEPVLFDGTIYENIKMGNE-HATHDQVVEACKMANANDFIKRLPDGYGTRVG 1575
R+Q+G+VSQEP+LF+ TI+ NI G + T ++++ K +NA++FI LP GY T VG
Sbjct: 1097 RDQMGLVSQEPILFNDTIHANIAYGRKGQVTEEEIIAVAKASNAHEFISSLPQGYNTTVG 1156
Query: 1576 EKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIV 1755
E+G QLSGGQKQRIAIARA++K+PKILLLDEATSALD E+ER VQ ALDQ RTTI+V
Sbjct: 1157 ERGTQLSGGQKQRIAIARAILKDPKILLLDEATSALDAESERIVQDALDQVMVSRTTIVV 1216
Query: 1756 AHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFY 1869
AHRLSTI+ D I V K G+I E G H+ LM G Y
Sbjct: 1217 AHRLSTIKGADVIAVIKDGSIAEKGQHDSLMRINGGVY 1254
>gi|25297456|pir||F86155 probable ABC transporter [imported] -
Arabidopsis thaliana
gi|9972377|gb|AAG10627.1| Putative ABC transporter [Arabidopsis
thaliana]
Length = 1229
Score = 793 bits (2047), Expect = 0.0
Identities = 451/1231 (36%), Positives = 682/1231 (54%), Gaps = 33/1231 (2%)
Frame = +1
Query: 148 LITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSE 327
+I G++ A+ +G PL+ ++ G + F + QN+ +V V
Sbjct: 1 MICGSLGAIGNGVCLPLMTLLFGDLIDSFGKNQNNKDIVDV------------------- 41
Query: 328 VVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQ-QTG 504
V K C+ ++ LG+ +++Q+AC+ ER K+R NYLK ILRQ I +FD + TG
Sbjct: 42 VSKVCLKFVYLGLGRLGAAFLQVACWMITGERQAAKIRSNYLKTILRQDIGFFDVETNTG 101
Query: 505 NLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSG 684
+ R++ D +++ +G+K +Q+ + F+ G+ + F W +TLVM+ P + ++G
Sbjct: 102 EVVGRMSGDTVHIQDAMGEKVGKFIQLVSTFVGGFALAFAKGWLLTLVMLTSIPFLAMAG 161
Query: 685 AKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGI 864
A M+ + + Q YA A + E+T SIRTV S G K+ ++ + + ++ I
Sbjct: 162 AAMALLVTRASSRGQAAYAKAATVVEQTIGSIRTVASFTGEKQAINSYKKYITSAYKSSI 221
Query: 865 VKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGA 1044
+ G+G+G +SSYALA W+G +I+ + + G + V V++GS SLG
Sbjct: 222 QQGFSTGLGLGVMIYVFFSSYALAIWFGGKMIL-EKGYTGGSVINVIIIVVAGSMSLGQT 280
Query: 1045 LPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIH 1224
P + +F + AA + I P ID Y + G ++ +++GDI KDVHF YP+R D
Sbjct: 281 SPCVTAFAAGQAAAYKMFETIKRKPLIDAYDVNGKVLGDIRGDIELKDVHFSYPARPDEE 340
Query: 1225 VLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLRE 1404
+ G SL + +G ALVG SG GKST++NL++RFYDP G VLIDG++L+E + +R
Sbjct: 341 IFDGFSLFIPSGATAALVGESGSGKSTVINLIERFYDPKAGEVLIDGINLKEFQLKWIRS 400
Query: 1405 QIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKG 1584
+IG+V QEPVLF +I ENI G E+AT ++ A ++ANA FI LP G T+VGE G
Sbjct: 401 KIGLVCQEPVLFSSSIMENIAYGKENATLQEIKVATELANAAKFINNLPQGLDTKVGEHG 460
Query: 1585 VQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHR 1764
QLSGGQKQRIAIARA++K+P++LLLDEATSALDTE+ER VQ ALD+ RTT++VAHR
Sbjct: 461 TQLSGGQKQRIAIARAILKDPRVLLLDEATSALDTESERVVQEALDRVMVNRTTVVVAHR 520
Query: 1765 LSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXXEAGKDIEDTISE 1944
LST+RN D I V +G +VE GSH EL+ Y +A + S
Sbjct: 521 LSTVRNADMIAVIHSGKMVEKGSHSELLKDSVGAYSQLIRCQEINKGHDAKPSDMASGSS 580
Query: 1945 SAHSHLXXXXXXXXXXXXXXXI------HQL-------------------AEEVEECKAP 2049
+S+L H L EE
Sbjct: 581 FRNSNLNISREGSVISGGTSSFGNSSRHHSLNVLGLFAGLDLGSGSQRVGQEETGTTSQE 640
Query: 2050 P---TSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANV 2220
P S+ +I N ++ ++ P+F ++ + + + PADQ++ +
Sbjct: 641 PLRKVSLTRIAALNKPEIPVLLLGTVVAAINGAIFPLFGILISRVIEAFFKPADQLKKDS 700
Query: 2221 YFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTG 2400
FW +FV +G+T + + G L +++ F+ + +++++D+ + +G
Sbjct: 701 RFWAIIFVALGVTSLIVSPSQMYLFAVAGGKLIRRIQSMCFEKAVHMEVSWFDEPENSSG 760
Query: 2401 KLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGG 2577
+ R +TDA +R V L + + + + L I F W+ + G
Sbjct: 761 TMGARLSTDAALIRALVGDALSLAVQNAASAASGLIIAFTASWELALIILVMLPLIGING 820
Query: 2578 YFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNL 2757
+ +++ G EEA +VA+ AV IRTV S +E+ Y + P +
Sbjct: 821 FLQVKFMKGFSADAKSKYEEASQVANDAVGSIRTVASFCAEEKVMQMYNKQCEGPIKDGV 880
Query: 2758 KHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTT 2937
K G F FS ++F +YA +FY + V IDV++VFFA++ I ++
Sbjct: 881 KQGFISGLGFGFSFFILFCVYATSFYAAARLVEDGKTTFIDVFQVFFALTMAAIGISQSS 940
Query: 2938 SFIPDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTKV 3114
+F PD KA++AA+ +F +I+ + IDS ++G +++ + G+I +R++ F YP R ++
Sbjct: 941 TFAPDSSKAKVAAASIFAIIDRKSKIDSSDETGTVLENVKGDIELRHLSFTYPARPGIQI 1000
Query: 3115 LQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQ 3294
+ L I+AGKTVALVG SG GKST++ LL+RFY+ D G I +DG ++ L + LR+Q
Sbjct: 1001 FRDLCLTIRAGKTVALVGESGSGKSTVISLLQRFYDPDSGQITLDGVELKKLQLKWLRQQ 1060
Query: 3295 VCIVSQEPTLFDCTIGENICY--GTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGE 3468
+ +V QEP LF+ TI NI Y G+ T EI+ AA++AN H FI + GYDT VGE
Sbjct: 1061 MGLVGQEPVLFNDTIRANIAYGKGSEEAATESEIIAAAELANAHKFISSIQQGYDTVVGE 1120
Query: 3469 KGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIA 3648
KG QLSGGQKQR+AIARA+V+ P +LLLDEATSALD ESE++VQ+ALD RT +V+A
Sbjct: 1121 KGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERLVQDALDRVIVNRTTVVVA 1180
Query: 3649 HRLSTIQNSDVIAIVSEGKIVEKGTHDELIR 3741
HRLSTI+N+DVIAIV G I E GTH+ LI+
Sbjct: 1181 HRLSTIKNADVIAIVKNGVIAENGTHETLIK 1211
Score = 375 bits (964), Expect = e-102
Identities = 213/583 (36%), Positives = 330/583 (56%), Gaps = 5/583 (0%)
Frame = +1
Query: 136 DLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDE 315
++ +L+ GTV A I+GA FPL I++ + F + D+
Sbjct: 657 EIPVLLLGTVVAAINGAIFPLFGILISRVIEAFFKPA---------------------DQ 695
Query: 316 FNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQ 495
+ + I ++ LGV S Q+ F +L+ +++ + + ++ WFD+
Sbjct: 696 LKKDSRFWAIIFVALGVTSLIVSPSQMYLFAVAGGKLIRRIQSMCFEKAVHMEVSWFDEP 755
Query: 496 Q--TGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPL 669
+ +G + ARL+ D +R +GD +L VQ A+ +G + F SW + L+++ PL
Sbjct: 756 ENSSGTMGARLSTDAALIRALVGDALSLAVQNAASAASGLIIAFTASWELALIILVMLPL 815
Query: 670 IVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVG 849
I ++G K M + + Y A +A + SIRTV S ++ + + E
Sbjct: 816 IGINGFLQVKFMKGFSADAKSKYEEASQVANDAVGSIRTVASFCAEEKVMQMYNKQCEGP 875
Query: 850 RQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGST 1029
+ G+ + G+G GFS ++ YA +F Y + ++ D +F VFFA+ +
Sbjct: 876 IKDGVKQGFISGLGFGFSFFILFCVYATSF-YAAARLVEDGKTTFIDVFQVFFALTMAAI 934
Query: 1030 SLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPS 1209
+ + A+ AA+++ +I+ KID G +++N+KGDI + + F YP+
Sbjct: 935 GISQSSTFAPDSSKAKVAAASIFAIIDRKSKIDSSDETGTVLENVKGDIELRHLSFTYPA 994
Query: 1210 RKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNV 1389
R I + + + L ++AG +ALVG SG GKST+++LLQRFYDP G++ +DGV+L+++ +
Sbjct: 995 RPGIQIFRDLCLTIRAGKTVALVGESGSGKSTVISLLQRFYDPDSGQITLDGVELKKLQL 1054
Query: 1390 HSLREQIGIVSQEPVLFDGTIYENIKMGN---EHATHDQVVEACKMANANDFIKRLPDGY 1560
LR+Q+G+V QEPVLF+ TI NI G E AT +++ A ++ANA+ FI + GY
Sbjct: 1055 KWLRQQMGLVGQEPVLFNDTIRANIAYGKGSEEAATESEIIAAAELANAHKFISSIQQGY 1114
Query: 1561 GTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGR 1740
T VGEKG+QLSGGQKQR+AIARA+VK PKILLLDEATSALD E+ER VQ ALD+ R
Sbjct: 1115 DTVVGEKGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERLVQDALDRVIVNR 1174
Query: 1741 TTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFY 1869
TT++VAHRLSTI+N D I + K G I E+G+HE L+ G Y
Sbjct: 1175 TTVVVAHRLSTIKNADVIAIVKNGVIAENGTHETLIKIDGGVY 1217
Score = 322 bits (826), Expect = 3e-86
Identities = 187/508 (36%), Positives = 276/508 (53%), Gaps = 2/508 (0%)
Frame = +1
Query: 2230 CGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLC 2409
C FV +G+ F C GE K+R K +LRQDI F+D + TG++
Sbjct: 46 CLKFVYLGLGRLGAAFLQVACWMITGERQAAKIRSNYLKTILRQDIGFFD-VETNTGEVV 104
Query: 2410 TRFATDAPNVRYVF-TRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFE 2586
R + D +++ ++ + + T G + F GW M G
Sbjct: 105 GRMSGDTVHIQDAMGEKVGKFIQLVSTFVGGFALAFAKGWLLTLVMLTSIPFLAMAGAAM 164
Query: 2587 MQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHA 2766
+ R +A V Q + IRTV S ++Q +Y +Y+ + ++++
Sbjct: 165 ALLVTRASSRGQAAYAKAATVVEQTIGSIRTVASFTGEKQAINSYKKYITSAYKSSIQQG 224
Query: 2767 HTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFI 2946
+ G + F YA A + G + ++ V V + +G T+ +
Sbjct: 225 FSTGLGLGVMIYVFFSSYALAIWFGGKMILEKGYTGGSVINVIIIVVAGSMSLGQTSPCV 284
Query: 2947 PDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTKVLQG 3123
+ AA +F I+ ID+ +G ++ I G+I +++V F+YP R D ++ G
Sbjct: 285 TAFAAGQAAAYKMFETIKRKPLIDAYDVNGKVLGDIRGDIELKDVHFSYPARPDEEIFDG 344
Query: 3124 FTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCI 3303
F+L I +G T ALVG SG GKST++ L+ERFY+ G ++IDG N++ + +R ++ +
Sbjct: 345 FSLFIPSGATAALVGESGSGKSTVINLIERFYDPKAGEVLIDGINLKEFQLKWIRSKIGL 404
Query: 3304 VSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQL 3483
V QEP LF +I ENI YG N T QEI A ++AN FI LP G DT VGE GTQL
Sbjct: 405 VCQEPVLFSSSIMENIAYG-KENATLQEIKVATELANAAKFINNLPQGLDTKVGEHGTQL 463
Query: 3484 SGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLST 3663
SGGQKQRIAIARA+++ P VLLLDEATSALDTESE++VQEALD RT +V+AHRLST
Sbjct: 464 SGGQKQRIAIARAILKDPRVLLLDEATSALDTESERVVQEALDRVMVNRTTVVVAHRLST 523
Query: 3664 IQNSDVIAIVSEGKIVEKGTHDELIRKS 3747
++N+D+IA++ GK+VEKG+H EL++ S
Sbjct: 524 VRNADMIAVIHSGKMVEKGSHSELLKDS 551
>gi|5456701|gb|AAD43626.1| multidrug resistance protein MDR
[Emericella nidulans]
gi|6856159|gb|AAF29805.1| ABC-transporter [Emericella nidulans]
Length = 1348
Score = 790 bits (2040), Expect = 0.0
Identities = 476/1263 (37%), Positives = 684/1263 (53%), Gaps = 32/1263 (2%)
Frame = +1
Query: 91 VKLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGV 270
V ++ +G++ Y +D+L+++ T+ A+ GA PL I+ G + + F R
Sbjct: 98 VNISFFGLWRYATKMDILIMVISTICAIAAGAALPLFTILFGSLASTFQRIM-------- 149
Query: 271 DNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNY 450
L IS DEF E+ K +Y++ LG+ F T YV F E K+R+ Y
Sbjct: 150 -------LYQISYDEFYDELTKNVLYFVYLGIGEFVTVYVSTVGFIYTGEHATQKIREYY 202
Query: 451 LKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYS 630
L++ILRQ I +FDK G +T R+T D +++G+ +K L + A F+ + + +
Sbjct: 203 LESILRQNIGYFDKLGAGEVTTRITADTNLIQDGISEKVGLTLTALATFVTAFIIAYVKY 262
Query: 631 WSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHK 810
W + L+ +VL+ S+ + ++ ++Y G +AEE SSIR +
Sbjct: 263 WKLALICSSTIVALVLTMGGGSQFIIKYSKKSLDSYGAGGTVAEEVISSIRNATAFGTQD 322
Query: 811 RELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGL 990
+ ++ L+ + G MG +G MYS+Y L FW GS ++ D D G
Sbjct: 323 KLAKQYEVHLDEAEKWGTKNQIVMGFMIGAMFGLMYSNYGLGFWMGSRFLV-DGAVDVGD 381
Query: 991 IFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKG 1170
I TV A+L GS SLG P+ +F A AA+ + I+ +DPYS EG +D+ +G
Sbjct: 382 ILTVLMAILIGSFSLGNVSPNAQAFTNAVAAAAKIFGTIDRQSPLDPYSNEGKTLDHFEG 441
Query: 1171 DISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGR 1350
I ++V YPSR ++ V++ +SL + AG ALVG SG GKST+V L++RFY P +G
Sbjct: 442 HIELRNVKHIYPSRPEVTVMEDVSLSMPAGKTTALVGPSGSGKSTVVGLVERFYMPVRGT 501
Query: 1351 VLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMG-----NEHATHDQVVE--- 1506
VL+DG D++++N+ LR+QI +VSQEPVLF TIY+NI+ G E+ + D+V E
Sbjct: 502 VLLDGHDIKDLNLRWLRQQISLVSQEPVLFGTTIYKNIRHGLIGTKYENESEDKVRELIE 561
Query: 1507 -ACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSAL 1683
A KMANA+DFI LP+GY T VG++G LSGGQKQRIAIARA+V +PKILLLDEATSAL
Sbjct: 562 NAAKMANAHDFITALPEGYETNVGQRGFLLSGGQKQRIAIARAVVSDPKILLLDEATSAL 621
Query: 1684 DTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGI 1863
DT++E VQ AL++A GRTTI++AHRLSTI+ I V G I E G+H+EL+ + G
Sbjct: 622 DTKSEGVVQAALERAAEGRTTIVIAHRLSTIKTAHNIVVLVNGKIAEQGTHDELVDRGGA 681
Query: 1864 FYDMT-XXXXXXXXXXEAGKDIE-------DTISESAHSHLXXXXXXXXXXXXXXXIHQL 2019
+ + +A +D + D S H+
Sbjct: 682 YRKLVEAQRINEQKEADALEDADAEDLTNADIAKIKTASSASSDLDGKPTTIDRTGTHKS 741
Query: 2020 AEEVEECKAPPTSMFK---------IFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAE 2172
K PP + K + FN ++ + P A++YA+
Sbjct: 742 VSSAILSKRPPETTPKYSLWTLLKFVASFNRPEIPYMLIGLVFSVLAGGGQPTQAVLYAK 801
Query: 2173 IFNVYSLPADQ---MQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAF 2343
+ SLP Q ++ + FW MF ++GI F+ T+ C E L + R AF
Sbjct: 802 AISTLSLPESQYSKLRHDADFWSLMFFVVGIIQFITQSTNGAAFAVCSERLIRRARSTAF 861
Query: 2344 KNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVF-TRLPVVLASIVTICGALGIGFYY 2520
+ +LRQDIAF+D + TG L + +T+ ++ V L +L + T+ A+ I
Sbjct: 862 RTILRQDIAFFDKEENSTGALTSFLSTETKHLSGVSGVTLGTILMTSTTLGAAIIIALAI 921
Query: 2521 GWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQ 2700
GW+ G++ M Q R E + A +A IRTV SL R+
Sbjct: 922 GWKLALVCISVVPVLLACGFYRFYMLAQFQSRSKLAYEGSANFACEATSSIRTVASLTRE 981
Query: 2701 EQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPID 2880
Y L T+L ++A SQ+L+FF A F+ G +
Sbjct: 982 RDVWEIYHAQLDAQGRTSLISVLRSSLLYASSQALVFFCVALGFWYGGTLLGHHEYDIFR 1041
Query: 2881 VYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITG 3057
+ F I F Q G SF PD+ KA+ AA+ L + ID+ S+ G ++ + G
Sbjct: 1042 FFVCFSEILFGAQSAGTVFSFAPDMGKAKNAAAEFRRLFDRKPQIDNWSEEGEKLETVEG 1101
Query: 3058 NISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGM 3237
I RNV F YPTR + VL+G L +K G+ VALVG SGCGKST + LLERFY+ G
Sbjct: 1102 EIEFRNVHFRYPTRPEQPVLRGLDLTVKPGQYVALVGPSGCGKSTTIALLERFYDAIAGS 1161
Query: 3238 IMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYG-TNRNVTYQEIVEAAKMAN 3414
I++DG +I LNI+S R + +VSQEPTL+ TI ENI G +V + +++A K AN
Sbjct: 1162 ILVDGKDISKLNINSYRSFLSLVSQEPTLYQGTIKENILLGIVEDDVPEEFLIKACKDAN 1221
Query: 3415 IHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKI 3594
I++FI+ LP+G++T VG KG LSGGQKQR+AIARAL+R P +LLLDEATSALD+ESEK+
Sbjct: 1222 IYDFIMSLPEGFNTVVGSKGGMLSGGQKQRVAIARALLRDPKILLLDEATSALDSESEKV 1281
Query: 3595 VQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCET 3774
VQ ALDAA +GRT + +AHRLSTIQ +DVI + +GKIVE GTH EL++K Y +
Sbjct: 1282 VQAALDAAARGRTTIAVAHRLSTIQKADVIYVFDQGKIVESGTHSELVQKKGRYYELVNL 1341
Query: 3775 QRI 3783
Q +
Sbjct: 1342 QSL 1344
Score = 331 bits (849), Expect = 7e-89
Identities = 204/544 (37%), Positives = 307/544 (55%), Gaps = 12/544 (2%)
Frame = +1
Query: 2200 DQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYD 2379
D++ NV + FV +GI FV + S GE T K+R +++LRQ+I ++D
Sbjct: 160 DELTKNVLY----FVYLGIGEFVTVYVSTVGFIYTGEHATQKIREYYLESILRQNIGYFD 215
Query: 2380 DLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIVTICGALGIGFYYGWQXXX--XXXX 2550
L G G++ TR D ++ + ++ + L ++ T A I + W+
Sbjct: 216 KL--GAGEVTTRITADTNLIQDGISEKVGLTLTALATFVTAFIIAYVKYWKLALICSSTI 273
Query: 2551 XXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEY 2730
MGG + +++ K+ D+ G VA + + IR + Q++ Y +
Sbjct: 274 VALVLTMGGGSQFIIKYSKKSLDSY--GAGGTVAEEVISSIRNATAFGTQDKLAKQYEVH 331
Query: 2731 LREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISF 2910
L E K+ G + L++ Y F++GS F+ A+ D+ V AI
Sbjct: 332 LDEAEKWGTKNQIVMGFMIGAMFGLMYSNYGLGFWMGSRFLVDGAVDVGDILTVLMAILI 391
Query: 2911 CGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFN 3087
+GN + A AA+ +F I+ +P+D S+ G + G+I +RNV
Sbjct: 392 GSFSLGNVSPNAQAFTNAVAAAAKIFGTIDRQSPLDPYSNEGKTLDHFEGHIELRNVKHI 451
Query: 3088 YPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRN 3267
YP+R + V++ +L + AGKT ALVG SG GKST++GL+ERFY +G +++DG +I++
Sbjct: 452 YPSRPEVTVMEDVSLSMPAGKTTALVGPSGSGKSTVVGLVERFYMPVRGTVLLDGHDIKD 511
Query: 3268 LNISSLREQVCIVSQEPTLFDCTIGENICYG-------TNRNVTYQEIVE-AAKMANIHN 3423
LN+ LR+Q+ +VSQEP LF TI +NI +G +E++E AAKMAN H+
Sbjct: 512 LNLRWLRQQISLVSQEPVLFGTTIYKNIRHGLIGTKYENESEDKVRELIENAAKMANAHD 571
Query: 3424 FILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQE 3603
FI LP+GY+T+VG++G LSGGQKQRIAIARA+V P +LLLDEATSALDT+SE +VQ
Sbjct: 572 FITALPEGYETNVGQRGFLLSGGQKQRIAIARAVVSDPKILLLDEATSALDTKSEGVVQA 631
Query: 3604 ALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRI 3783
AL+ A +GRT +VIAHRLSTI+ + I ++ GKI E+GTHDEL+ + Y+K E QRI
Sbjct: 632 ALERAAEGRTTIVIAHRLSTIKTAHNIVVLVNGKIAEQGTHDELVDRGGAYRKLVEAQRI 691
Query: 3784 VESQ 3795
E +
Sbjct: 692 NEQK 695
>gi|17567265|ref|NP_510126.1| P-GlycoProtein related (pgp-12)
[Caenorhabditis elegans]
gi|7499663|pir||T21266 hypothetical protein F22E10.1 - Caenorhabditis
elegans
gi|3876291|emb|CAA91799.1| Hypothetical protein F22E10.1
[Caenorhabditis elegans]
Length = 1318
Score = 785 bits (2027), Expect = 0.0
Identities = 464/1263 (36%), Positives = 694/1263 (54%), Gaps = 36/1263 (2%)
Frame = +1
Query: 97 LTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDN 276
+T G+F Y + D LL G + I G P L I+ G +T L + N
Sbjct: 76 VTLLGLFRYAERTDYALLCFGIFLSFISGIAQPGLGIIAGNITNSLL----------IHN 125
Query: 277 VNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLK 456
D+F + + +G+++ ++VQ CF+ R+ K++Q+Y++
Sbjct: 126 ATS--------DDFYDSAMTNVWLFGGIGIIVLIVNFVQYMCFQYCCIRITSKMKQHYIQ 177
Query: 457 AILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWS 636
+ILRQ WFDK +G LT +L D++ER+ EG+GDK +L++ F+AG + FFY W
Sbjct: 178 SILRQNAGWFDKNHSGTLTTKLHDNMERINEGIGDKLGVLIRGMVMFVAGIVISFFYEWR 237
Query: 637 MTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRE 816
+ L+MMG PL + + MS+SM++ T E AG+IAEE+ +RTV + NG +
Sbjct: 238 LALMMMGIGPLCCVCMSLMSRSMSSFTSKELAGVGKAGSIAEESLMGVRTVQAFNGQEEM 297
Query: 817 LDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIF 996
++++ L G+ I K + G+ G L ++S + +YG L+ G +F
Sbjct: 298 VEKYTVELGKGKSFAIQKGLWGGVFGGIFLLFLFSYFGGGIYYGGQLLRWKIIETPGDVF 357
Query: 997 TVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDI 1176
V ++L G+ LG PHL AR AA+T+ +I+ P ID YS EG + N+ G +
Sbjct: 358 IVVISMLIGAYFLGLISPHLMVLLNARVAAATIYEIIDRTPDIDVYSTEGQKMTNVVGKV 417
Query: 1177 SFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVL 1356
F++VHFRYP+RK + VL G++L +K G +ALVG SGCGKST V LL R Y+P G+V+
Sbjct: 418 VFEEVHFRYPTRKKVKVLNGLNLTVKPGTSVALVGHSGCGKSTSVGLLTRLYEPEGGKVM 477
Query: 1357 IDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDF 1536
IDG D+R +N+ LR+ +GIV QEP+LF+ TI+ N+ +GN AT + ++ CKMANA+DF
Sbjct: 478 IDGQDVRSLNIDWLRKTVGIVQQEPILFNDTIHNNLLIGNPSATREDMIRVCKMANAHDF 537
Query: 1537 IKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGA 1716
I+++P+GY T +G+ VQLSGGQKQR+AIAR L+++PK+LLLDEATSALD ++E VQ A
Sbjct: 538 IQKMPNGYETMIGDGSVQLSGGQKQRVAIARTLIRDPKVLLLDEATSALDAQSESVVQSA 597
Query: 1717 LDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXX---X 1887
L+ A GRTTI++AHRLSTIR D+I F+ G IVESG+HEEL++ G + +
Sbjct: 598 LNNAAKGRTTIMIAHRLSTIREADKIVFFENGVIVESGNHEELVALGGRYAKLVEAQKFK 657
Query: 1888 XXXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQL---------------- 2019
+ E+T + H L L
Sbjct: 658 ESDDIEDNGDEHEEETSTVGRHDRLSSRQVSFHKSCESLASADLEIGYASTFNTFTLKTA 717
Query: 2020 ---------AEEV----EECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFAL 2160
AEEV EE + IFK + S + A
Sbjct: 718 QEEIENEDFAEEVQRVMEEDGVINSGYLDIFKNAQGNYLYLSVGTFFAILRGSELALLAN 777
Query: 2161 VYAEIFNVYSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEA 2340
++ +F + P D+M + ++V +G+ F+ S E+L +K R ++
Sbjct: 778 MFGFVFAAFKEPEDEMVKALGLIFILYVALGLFVFITQVISGTLFTIVAENLGLKFRVQS 837
Query: 2341 FKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVF-TRLPVVLASIVTICGALGIGFY 2517
FKNLL QD +F+D+ H GKL TR A+DAPNV+ V TR+ V+ SI +I L G+
Sbjct: 838 FKNLLYQDASFFDNPAHAPGKLITRLASDAPNVKAVVDTRMLQVIYSITSITINLITGYI 897
Query: 2518 YGWQXXXXXX---XXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHS 2688
+ W+ + +++ KQIR +EAGK+A + +E ++T+
Sbjct: 898 FCWRIAIAGTIMIVLFATMMISMAYKIARENLKQIRK----DEAGKIAIEIIESVKTIQL 953
Query: 2689 LNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAM 2868
L ++F Y + + ++ ++ A SQ+ ++F + +G+ + +
Sbjct: 954 LTSTQRFLTHYKDAQLVQHKSEMRKSYIQSVNNAISQTFMYFAMFVCYGVGTPLMYHGIV 1013
Query: 2869 QPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKP 3048
+ +R + + +++ P+ VKA+ AA +LF LI + + + G
Sbjct: 1014 EAEPTFRAINCMMMGSVAVMHSSHNFPEFVKAKTAAGMLFKLIYRKSKTGDVME-GNNTE 1072
Query: 3049 ITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQD 3228
I GN+ +V F+YP R V+ +G+TVALVG SG GKST + +LERFY+
Sbjct: 1073 IRGNVLFESVKFSYPQRPMQPVMTDLHFSAHSGQTVALVGPSGTGKSTCIAMLERFYDVS 1132
Query: 3229 KGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKM 3408
G + IDG NI++L++ LR Q+ +V QEP LF TI EN+C+G ++V+ +++ +A ++
Sbjct: 1133 GGALRIDGQNIKSLSLHHLRTQMALVGQEPRLFAGTIKENVCFGL-KDVSVEKVHQALEL 1191
Query: 3409 ANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESE 3588
AN F+ LP G DT VGEKG QLSGGQKQRIAIARALVR P +LLLDEATSALD+ESE
Sbjct: 1192 ANASRFLANLPAGIDTEVGEKGGQLSGGQKQRIAIARALVRDPKILLLDEATSALDSESE 1251
Query: 3589 KIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFC 3768
+ VQEALD A++GRTC+ IAHRLS+IQNSD+I + G + E G H L+ Y
Sbjct: 1252 RAVQEALDRAREGRTCITIAHRLSSIQNSDLIVYIDHGMVQEAGNHAHLMSLRGKYYNLI 1311
Query: 3769 ETQ 3777
+ Q
Sbjct: 1312 KKQ 1314
Score = 314 bits (804), Expect = 1e-83
Identities = 190/539 (35%), Positives = 298/539 (55%), Gaps = 8/539 (1%)
Frame = +1
Query: 2200 DQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYD 2379
D NV+ + G+ +++ I FV + C C +T K++ +++LRQ+ ++D
Sbjct: 133 DSAMTNVWLFGGIGIIVLIVNFVQYM----CFQYCCIRITSKMKQHYIQSILRQNAGWFD 188
Query: 2380 DLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXX 2556
++ +G L T+ + + + +L V++ +V + I F+Y W+
Sbjct: 189 --KNHSGTLTTKLHDNMERINEGIGDKLGVLIRGMVMFVAGIVISFFYEWRLALMMMGIG 246
Query: 2557 XXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLR 2736
+ + ++ + +AG +A +++ +RTV + N QE+ Y L
Sbjct: 247 PLCCVCMSLMSRSMSSFTSKELAGVGKAGSIAEESLMGVRTVQAFNGQEEMVEKYTVELG 306
Query: 2737 EPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQ------PIDVYRVFF 2898
+ + ++ +G VF IF ++ +++ G I+ Q ++ P DV+ V
Sbjct: 307 KGKSFAIQKG-LWGGVFGG----IFLLFLFSYFGGGIYYGGQLLRWKIIETPGDVFIVVI 361
Query: 2899 AISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGI-VKPITGNISIRN 3075
++ +G + + ++ AR+AA+ ++ +I+ ID S G + + G +
Sbjct: 362 SMLIGAYFLGLISPHLMVLLNARVAAATIYEIIDRTPDIDVYSTEGQKMTNVVGKVVFEE 421
Query: 3076 VFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGD 3255
V F YPTRK KVL G L +K G +VALVGHSGCGKST +GLL R Y + G +MIDG
Sbjct: 422 VHFRYPTRKKVKVLNGLNLTVKPGTSVALVGHSGCGKSTSVGLLTRLYEPEGGKVMIDGQ 481
Query: 3256 NIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILG 3435
++R+LNI LR+ V IV QEP LF+ TI N+ G N + T ++++ KMAN H+FI
Sbjct: 482 DVRSLNIDWLRKTVGIVQQEPILFNDTIHNNLLIG-NPSATREDMIRVCKMANAHDFIQK 540
Query: 3436 LPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDA 3615
+P+GY+T +G+ QLSGGQKQR+AIAR L+R P VLLLDEATSALD +SE +VQ AL+
Sbjct: 541 MPNGYETMIGDGSVQLSGGQKQRVAIARTLIRDPKVLLLDEATSALDAQSESVVQSALNN 600
Query: 3616 AKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRIVES 3792
A +GRT ++IAHRLSTI+ +D I G IVE G H+EL+ Y K E Q+ ES
Sbjct: 601 AAKGRTTIMIAHRLSTIREADKIVFFENGVIVESGNHEELVALGGRYAKLVEAQKFKES 659
>gi|15234323|ref|NP_192092.1| multidrug resistance P-glycoprotein,
putative [Arabidopsis thaliana]
gi|25297454|pir||E85023 probable P-glycoprotein-like protein
[imported] - Arabidopsis thaliana
gi|4558552|gb|AAD22645.1| putative P-glycoprotein-like protein
[Arabidopsis thaliana]
gi|7268567|emb|CAB80676.1| putative P-glycoprotein-like protein
[Arabidopsis thaliana]
Length = 1230
Score = 784 bits (2025), Expect = 0.0
Identities = 445/1216 (36%), Positives = 685/1216 (55%), Gaps = 5/1216 (0%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNP 285
Y +F+++ D+LL+I G++ A+ +G PL+ ++ G + QN++ +V
Sbjct: 16 YKLFFFSDSTDVLLMIVGSIGAIANGVCSPLMTLLFGELIDAMGPNQNNEEIV------- 68
Query: 286 EGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAIL 465
V K C+ + LG+ +++Q+AC+ ER ++R YLK IL
Sbjct: 69 ------------ERVSKVCLSLVYLGLGALGAAFLQVACWMITGERQAARIRSLYLKTIL 116
Query: 466 RQQIQWFDKQQT-GNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMT 642
RQ I +FD + T G + R++ D + + +G+K +Q+ + F+ G+ + F W +T
Sbjct: 117 RQDIGFFDVEMTTGEVVGRMSGDTVLILDAMGEKVGKFIQLISTFVGGFVIAFLRGWLLT 176
Query: 643 LVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELD 822
LVM+ PL+ +SGA ++ + + EQ YA A + E+T SIRTV S G K+ +
Sbjct: 177 LVMLTSIPLLAMSGAAIAIIVTRASSQEQAAYAKASNVVEQTLGSIRTVASFTGEKQAMS 236
Query: 823 RFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTV 1002
+ + + ++ + + G+G+G L +S+YAL W+G +I+ + G + V
Sbjct: 237 SYKELINLAYKSNVKQGFVTGLGLGVMFLVFFSTYALGTWFGGEMILRKG-YTGGAVINV 295
Query: 1003 FFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISF 1182
V+S S +LG A P L +F + AA + I P ID + L G ++++++G+I
Sbjct: 296 MVTVVSSSIALGQASPCLTAFTAGKAAAYKMFETIEREPLIDTFDLNGKVLEDIRGEIEL 355
Query: 1183 KDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLID 1362
+DV F YP+R V G SL + +G ALVG SG GKST+++L++RFYDP G+VLID
Sbjct: 356 RDVCFSYPARPKEEVFGGFSLLIPSGTTTALVGESGSGKSTVISLIERFYDPNSGQVLID 415
Query: 1363 GVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIK 1542
GVDL+E + +R +IG+VSQEPVLF +I ENI G E AT +++ A K+ANA FI
Sbjct: 416 GVDLKEFQLKWIRGKIGLVSQEPVLFSSSIMENIGYGKEGATVEEIQAASKLANAAKFID 475
Query: 1543 RLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALD 1722
+LP G T VGE G QLSGGQKQRIAIARA++K+P+ILLLDEATSALD E+ER VQ ALD
Sbjct: 476 KLPLGLETLVGEHGTQLSGGQKQRIAIARAILKDPRILLLDEATSALDAESERVVQEALD 535
Query: 1723 QAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXX 1902
+ RTT+IVAHRLST+RN D I V G IVE GSH EL+ Y
Sbjct: 536 RIMVNRTTVIVAHRLSTVRNADIIAVIHRGKIVEEGSHSELLKDHEGAYSQLLRLQEINK 595
Query: 1903 XXEAGKDIEDTISE-SAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKAPPTSMFKIFKF 2079
+ + + +IS S+ + Q + ++ + + S +I
Sbjct: 596 ESKRLEISDGSISSGSSRGNNSTRQDDDSFSVLGLLAGQDSTKMSQELSQKVSFTRIAAL 655
Query: 2080 NGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANVYFWCGMFVLMGIT 2259
N ++ ++ P+F +++A++ + +++ + FW +FVL+G+
Sbjct: 656 NKPEIPILILGTLVGAVNGTIFPIFGILFAKVIEAFFKAPHELKRDSRFWSMIFVLLGVA 715
Query: 2260 FFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNV 2439
+ + T+ G L ++R F+ ++ ++ ++D+ + +G + R + DA +
Sbjct: 716 AVIVYPTTNYLFAIAGGRLIRRIRSMCFEKVVHMEVGWFDEPGNSSGAMGARLSADAALI 775
Query: 2440 R-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIR 2616
R V L + + ++ ++ L I F W+ + GY +++ G
Sbjct: 776 RTLVGDSLCLSVKNVASLVTGLIIAFTASWEVAIIILVIIPFIGINGYIQIKFMKGFSAD 835
Query: 2617 DTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFS 2796
EEA +VA+ AV IRTV S +E+ Y + + + +K G F S
Sbjct: 836 AKAKYEEASQVANDAVGSIRTVASFCAEEKVMEMYKKRCEDTIKSGIKQGLISGVGFGIS 895
Query: 2797 QSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAA 2976
+++ +YA+ FY+G+ V DV++VF A++ I +SF PD K + AA
Sbjct: 896 FFVLYSVYASCFYVGARLVKAGRTNFNDVFQVFLALTLTAVGISQASSFAPDSSKGKGAA 955
Query: 2977 SLLFYLIEHPTPIDSLSDSGIV-KPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKT 3153
+F +I+ + IDS +SG+V + + G+I + ++ F Y TR D +V + L I+AG+T
Sbjct: 956 VSIFRIIDRISKIDSRDESGMVLENVKGDIELCHISFTYQTRPDVQVFRDLCLSIRAGQT 1015
Query: 3154 VALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDC 3333
VALVG SG GKST++ LL+RFY+ D G I +DG ++ L + LR+Q+ +V QEP LF+
Sbjct: 1016 VALVGESGSGKSTVISLLQRFYDPDSGHITLDGVELKKLRLKWLRQQMGLVGQEPVLFND 1075
Query: 3334 TIGENICYGT-NRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIA 3510
TI NI YG T EI+ A+++AN H FI + GYDT VGE+G QLSGGQKQR+A
Sbjct: 1076 TIRANIAYGKGGEEATEAEIIAASELANAHRFISSIQKGYDTVVGERGIQLSGGQKQRVA 1135
Query: 3511 IARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAI 3690
IARA+V+ P +LLLDEATSALD ESE++VQ+ALD RT +V+AHRLSTI+N+DVIA+
Sbjct: 1136 IARAIVKEPKILLLDEATSALDAESERVVQDALDRVMVNRTTIVVAHRLSTIKNADVIAV 1195
Query: 3691 VSEGKIVEKGTHDELI 3738
V G I EKGTH+ LI
Sbjct: 1196 VKNGVIAEKGTHETLI 1211
Score = 369 bits (947), Expect = e-100
Identities = 211/582 (36%), Positives = 326/582 (55%), Gaps = 4/582 (0%)
Frame = +1
Query: 136 DLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDE 315
++ +LI GT+ ++G FP+ I+ + F +A + E
Sbjct: 659 EIPILILGTLVGAVNGTIFPIFGILFAKVIEAFFKAPH---------------------E 697
Query: 316 FNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDK- 492
+ + + +++LGV F RL+ ++R + ++ ++ WFD+
Sbjct: 698 LKRDSRFWSMIFVLLGVAAVIVYPTTNYLFAIAGGRLIRRIRSMCFEKVVHMEVGWFDEP 757
Query: 493 -QQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPL 669
+G + ARL+ D +R +GD L V+ A+ + G + F SW + ++++ P
Sbjct: 758 GNSSGAMGARLSADAALIRTLVGDSLCLSVKNVASLVTGLIIAFTASWEVAIIILVIIPF 817
Query: 670 IVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVG 849
I ++G K M + + Y A +A + SIRTV S ++ ++ + E
Sbjct: 818 IGINGYIQIKFMKGFSADAKAKYEEASQVANDAVGSIRTVASFCAEEKVMEMYKKRCEDT 877
Query: 850 RQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGST 1029
++GI + G+G G S +YS YA F+ G+ L+ T + +F VF A+ +
Sbjct: 878 IKSGIKQGLISGVGFGISFFVLYSVYASCFYVGARLVKAGRT-NFNDVFQVFLALTLTAV 936
Query: 1030 SLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPS 1209
+ A +GAA ++ R+I+ KID G++++N+KGDI + F Y +
Sbjct: 937 GISQASSFAPDSSKGKGAAVSIFRIIDRISKIDSRDESGMVLENVKGDIELCHISFTYQT 996
Query: 1210 RKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNV 1389
R D+ V + + L ++AG +ALVG SG GKST+++LLQRFYDP G + +DGV+L+++ +
Sbjct: 997 RPDVQVFRDLCLSIRAGQTVALVGESGSGKSTVISLLQRFYDPDSGHITLDGVELKKLRL 1056
Query: 1390 HSLREQIGIVSQEPVLFDGTIYENIKMGN--EHATHDQVVEACKMANANDFIKRLPDGYG 1563
LR+Q+G+V QEPVLF+ TI NI G E AT +++ A ++ANA+ FI + GY
Sbjct: 1057 KWLRQQMGLVGQEPVLFNDTIRANIAYGKGGEEATEAEIIAASELANAHRFISSIQKGYD 1116
Query: 1564 TRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRT 1743
T VGE+G+QLSGGQKQR+AIARA+VK PKILLLDEATSALD E+ER VQ ALD+ RT
Sbjct: 1117 TVVGERGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERVVQDALDRVMVNRT 1176
Query: 1744 TIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFY 1869
TI+VAHRLSTI+N D I V K G I E G+HE L++ +G Y
Sbjct: 1177 TIVVAHRLSTIKNADVIAVVKNGVIAEKGTHETLINIEGGVY 1218
Score = 301 bits (772), Expect = 6e-80
Identities = 190/552 (34%), Positives = 288/552 (51%), Gaps = 5/552 (0%)
Frame = +1
Query: 2143 TPVFALVYAEIFNVY--SLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESL 2316
+P+ L++ E+ + + +++ V C V +G+ F C GE
Sbjct: 44 SPLMTLLFGELIDAMGPNQNNEEIVERVSKVCLSLVYLGLGALGAAFLQVACWMITGERQ 103
Query: 2317 TMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVF-TRLPVVLASIVTIC 2493
++R K +LRQDI F+D + TG++ R + D + ++ + I T
Sbjct: 104 AARIRSLYLKTILRQDIGFFD-VEMTTGEVVGRMSGDTVLILDAMGEKVGKFIQLISTFV 162
Query: 2494 GALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHI 2673
G I F GW M G + ++ +A V Q + I
Sbjct: 163 GGFVIAFLRGWLLTLVMLTSIPLLAMSGAAIAIIVTRASSQEQAAYAKASNVVEQTLGSI 222
Query: 2674 RTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFV 2853
RTV S ++Q +Y E + + +N+K G + F YA + G +
Sbjct: 223 RTVASFTGEKQAMSSYKELINLAYKSNVKQGFVTGLGLGVMFLVFFSTYALGTWFGGEMI 282
Query: 2854 NQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDS 3033
++ V V + +G + + + AA +F IE ID+ +
Sbjct: 283 LRKGYTGGAVINVMVTVVSSSIALGQASPCLTAFTAGKAAAYKMFETIEREPLIDTFDLN 342
Query: 3034 G-IVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLE 3210
G +++ I G I +R+V F+YP R +V GF+L I +G T ALVG SG GKST++ L+E
Sbjct: 343 GKVLEDIRGEIELRDVCFSYPARPKEEVFGGFSLLIPSGTTTALVGESGSGKSTVISLIE 402
Query: 3211 RFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEI 3390
RFY+ + G ++IDG +++ + +R ++ +VSQEP LF +I ENI YG T +EI
Sbjct: 403 RFYDPNSGQVLIDGVDLKEFQLKWIRGKIGLVSQEPVLFSSSIMENIGYG-KEGATVEEI 461
Query: 3391 VEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSA 3570
A+K+AN FI LP G +T VGE GTQLSGGQKQRIAIARA+++ P +LLLDEATSA
Sbjct: 462 QAASKLANAAKFIDKLPLGLETLVGEHGTQLSGGQKQRIAIARAILKDPRILLLDEATSA 521
Query: 3571 LDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSE 3750
LD ESE++VQEALD RT +++AHRLST++N+D+IA++ GKIVE+G+H EL++ E
Sbjct: 522 LDAESERVVQEALDRIMVNRTTVIVAHRLSTVRNADIIAVIHRGKIVEEGSHSELLKDHE 581
Query: 3751 -IYQKFCETQRI 3783
Y + Q I
Sbjct: 582 GAYSQLLRLQEI 593
>gi|13641444|gb|AAK31736.1| p-glycoprotein [Mucor racemosus]
Length = 1292
Score = 784 bits (2024), Expect = 0.0
Identities = 466/1279 (36%), Positives = 707/1279 (54%), Gaps = 50/1279 (3%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNP 285
+ +F + DLLL+ + GA P+ + G + L+ V G D
Sbjct: 38 FRLFQFATTRDLLLICIAGFCSCTTGAIQPISILFFGNV----LKKLGEAIVEGND---- 89
Query: 286 EGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAIL 465
L E ++K +Y LG + +Y+ + E ++RQ Y+ +IL
Sbjct: 90 -------LMEATMPIIKLYVY---LGTGVMTAAYISNCLWVLTGENQARRIRQLYVHSIL 139
Query: 466 RQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTL 645
RQ++ WFDK + G+LT RL+ D++ +++G+ +KF + FA F+AG V F W +++
Sbjct: 140 RQEMSWFDKSEEGSLTTRLSADVQLIQDGISEKFGQFLMCFAQFIAGCSVAFSKGWRLSI 199
Query: 646 VMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDR 825
VM+ P I +G M + T Q+ YA AG+I+E+ F+ IRTV+S + R R
Sbjct: 200 VMIAVTPAIACTGGVMGILVTKYTVETQDAYADAGSISEQVFAGIRTVYSFSLQNRFAKR 259
Query: 826 FYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVF 1005
+ L+ + GI + +G G+G C+++ Y L+FWYGS L+ +D D + VF
Sbjct: 260 YEEKLDKAMRAGIKRGIILGTGLGIFMFCLFAMYGLSFWYGSRLV-HDHIMDGSTVLVVF 318
Query: 1006 FAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFK 1185
+++ G SL +LA+ +A AA + I P ID S +G++ + G++ FK
Sbjct: 319 LSMMMGEFSLLQLPTNLAAVSSASAAAYKIFETIKRVPDIDTSSPDGVIPSQVLGELEFK 378
Query: 1186 DVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDG 1365
V FRYP+R D +LK +SL++K G +A VG SG GKST V LLQRFYDP G V +DG
Sbjct: 379 HVKFRYPTRPDTIILKDLSLKIKPGMTVAFVGPSGSGKSTSVQLLQRFYDPMSGSVSLDG 438
Query: 1366 VDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHA--THDQVVEACKMANANDFI 1539
+L+E+NV LR+QIG+VSQEPVLF+ +I +N+ MG+E+ + +++ ACK AN + FI
Sbjct: 439 KNLKELNVKWLRQQIGVVSQEPVLFNTSIRQNLMMGSENRNISMEEITAACKKANCHSFI 498
Query: 1540 KRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGAL 1719
K+LP GY T VGE G LSGGQKQRIAIARA++KNP ILLLDEATSALDT++ER VQ AL
Sbjct: 499 KQLPKGYSTLVGEHGGMLSGGQKQRIAIARAILKNPAILLLDEATSALDTQSERLVQKAL 558
Query: 1720 DQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM-------T 1878
D+A A RTTI+VAHRLST+RN D I V + G+++E G+H++L++K G++ ++ T
Sbjct: 559 DEAAANRTTIVVAHRLSTVRNADLIVVMQHGDLIEQGTHDDLIAKGGVYSELVKKQQIQT 618
Query: 1879 XXXXXXXXXXEAGKDIEDTI---SESAHSHLXXXXXXXXXXXXXXXI------------- 2010
+ ++ ED I +E+ + I
Sbjct: 619 SSNNTHNRKTKQEEEQEDEILLRNEAMEVNRKSCIELNRASNNASIISVPAARKSRFSVL 678
Query: 2011 ----------HQLAEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFAL 2160
+ E+ + KAP ++K+F + GW +V P++AL
Sbjct: 679 DGFGREAASRKEAQEKHAKMKAP---VWKVFMQMRPQWGWCMLGSIGACIAGTVFPLYAL 735
Query: 2161 VYAEIFNVYSLPADQMQA-----NVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMK 2325
+A++ + + D+ N+Y + +FV++G+ F+GF G T
Sbjct: 736 FFAKVITMLNENDDKDYGPMEGPNMYSF--LFVILGMFAFLGFALQTVSFEIAGAKYTKT 793
Query: 2326 LRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVFTRL-PVVLASIVTICGAL 2502
LR F + ++Q+I ++D + G L ++ A DA NV + TR P V+ T +
Sbjct: 794 LRSMLFVSFMKQEIGYFDRDENNVGSLTSKLAVDAKNVNEMITRAWPDVVQIAFTSAIGM 853
Query: 2503 GIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTV 2682
I F + W+ + +++ G + + E++ +VAS+A++ IRTV
Sbjct: 854 TIAFMHSWKLTLIIMCMTPLIVGAAGWNSKVQEGFEGSTKEANEQSAEVASEAIKEIRTV 913
Query: 2683 HSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQ 2862
+LN+Q F Y P + A+T FA Q + A AFY GS + Q
Sbjct: 914 TALNKQSYFEERYYNATERPHRLAQRKAYTSSIGFALLQGTSLYTNAVAFYAGSKLITQG 973
Query: 2863 AMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIV 3042
+ D+ +I +G ++ F+ KA++AA F ++ IDS + +
Sbjct: 974 NLDLSDMVITMMSIMIMADGVGRSSIFVSTFAKAKIAAITTFEVLNRQPAIDSELEG--I 1031
Query: 3043 KP----ITGNISIRNVFFNYPTRKDTKVLQG-FTLDIKAGKTVALVGHSGCGKSTIMGLL 3207
+P I G+I ++ F YP R D + G F L K G+T+ALVG SG GKST +G+L
Sbjct: 1032 EPEGEDIDGDIDFSSIAFRYPARPDIPIFDGEFNLKGKQGQTIALVGPSGSGKSTTIGML 1091
Query: 3208 ERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGT--NRNVTY 3381
+R+Y+ G + +D N+++ + +LR + +VSQEPTLFD TIGENI +G ++ VT
Sbjct: 1092 QRWYDPLSGTVRVDNHNVKSYTLGNLRSHMALVSQEPTLFDMTIGENIRFGVDDSKEVTQ 1151
Query: 3382 QEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEA 3561
+E+ K ANIHNFI+ LP GYD VG+KG+QLSGGQKQRIAIARAL+R P +LLLDEA
Sbjct: 1152 EEVEAVCKSANIHNFIVSLPKGYDQRVGDKGSQLSGGQKQRIAIARALIRKPKILLLDEA 1211
Query: 3562 TSALDTESEKIVQEALDAAKQ--GRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDEL 3735
TSALD+ESEK+VQ+ALD Q GRT + IAHRLSTI N+D+I ++ +GK++E+G H +L
Sbjct: 1212 TSALDSESEKLVQKALDNIIQEGGRTTITIAHRLSTITNADLICVIKDGKVIEQGNHWQL 1271
Query: 3736 IRKSEIYQKFCETQRIVES 3792
++ +Y+ + Q + S
Sbjct: 1272 LKLDGVYKSLVQQQSLSSS 1290
>gi|2673951|gb|AAB88657.1| multidrug resistance protein 1 [Aspergillus
fumigatus]
gi|2673953|gb|AAB88658.1| multidrug resistance protein 1 [Aspergillus
fumigatus]
Length = 1349
Score = 783 bits (2022), Expect = 0.0
Identities = 464/1271 (36%), Positives = 693/1271 (54%), Gaps = 39/1271 (3%)
Frame = +1
Query: 88 TVKLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVG 267
+VK++ + ++ Y D+L+++ + A+ GA PL I+ G + + F G
Sbjct: 91 SVKVSFFTLYRYASRKDILIILVSAICAIAAGAALPLFTILFGSLASAFQ---------G 141
Query: 268 VDNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQN 447
+ L + EF ++ K +Y++ LG+ F T YV F E L K+R+N
Sbjct: 142 IS------LGTMPYHEFYHKLTKNVLYFVYLGIAEFVTVYVSTVGFIYTGEHLTQKIREN 195
Query: 448 YLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFY 627
YL+AILRQ + +FDK G +T R+T D +++ + +K L + FA F+ + V +
Sbjct: 196 YLEAILRQNMAYFDKLGAGEVTTRITADTNLIQDAISEKVGLTLTAFATFVTAFIVAYVK 255
Query: 628 SWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGH 807
W + L+ +V+ S+ + ++ E+Y G +AEE SSIR +
Sbjct: 256 YWKLALICTSTIVALVMVMGGGSRFIVKYSKKSIESYGAGGTVAEEVISSIRNATAFGTQ 315
Query: 808 KRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRG 987
+ ++ L + G+ + +G+ +G M+S+Y L FW GS ++ + G
Sbjct: 316 DKLAKQYETHLAEAEKWGVKQQVILGMMIGGMFGIMFSNYGLGFWMGSRFVVGKEV-NVG 374
Query: 988 LIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMK 1167
+ TV ++L GS SLG P+ +F AA+ + I+ +DPYS EG ++D+ +
Sbjct: 375 QVLTVLMSILIGSFSLGNVAPNGQAFTNGVAAAAKIYSTIDRRSPLDPYSDEGKVLDHFE 434
Query: 1168 GDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKG 1347
G+I F++V YPSR ++ V++ +SL + AG ALVG SG GKST+V L++RFY P G
Sbjct: 435 GNIEFRNVKHIYPSRPEVTVMEDVSLSMPAGKTTALVGPSGSGKSTVVGLVERFYLPVGG 494
Query: 1348 RVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGN-----EHATHDQVVE-- 1506
+VL+DG D++ +N+ LR+QI +VSQEPVLF TI+ NI+ G EH + D++ E
Sbjct: 495 QVLLDGHDIQTLNLRWLRQQISLVSQEPVLFSTTIFRNIEHGLIGTKFEHESKDKIRELV 554
Query: 1507 --ACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSA 1680
A +MANA+DFI LP+GY T VG++G LSGGQKQRIAIARA+V +PKILLLDEATSA
Sbjct: 555 ENAARMANAHDFIMALPEGYDTNVGQRGFLLSGGQKQRIAIARAIVSDPKILLLDEATSA 614
Query: 1681 LDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQG 1860
LDT++E VQ ALD+A GRTTI++AHRLSTI+ I G I E G+H+EL+ ++G
Sbjct: 615 LDTKSEGVVQAALDKAAEGRTTIVIAHRLSTIKTAHNIVAMVGGKIAEQGTHDELVDRKG 674
Query: 1861 IFYDMTXX------XXXXXXXXEAGKDIED----------TISESAHSHLXXXXXXXXXX 1992
+Y + +A D +D T S++S
Sbjct: 675 TYYKLVEAQRINEEKEAEALEADADMDADDFGQEGVTRIKTAVSSSNSLDAVDEKARLEM 734
Query: 1993 XXXXXIHQLAEEVEECKAPPT----SMFKIFK----FNGDKVGWXXXXXXXXXXXXSVTP 2148
++ V K P S++ + K FN ++G+ P
Sbjct: 735 KRTGTQKSVSSAVLSKKVPEQFEKYSLWTLVKFIGAFNRPELGYMLIGLTFSFLAGGGQP 794
Query: 2149 VFALVYAEIFNVYSLPAD---QMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLT 2319
A +YA+ + SLP +++ + FW MF ++GI F+ + C E L
Sbjct: 795 TQAFLYAKAISTLSLPESMFHKLRHDANFWSLMFFVVGIAQFISLSINGTAFAICSERLI 854
Query: 2320 MKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVF-TRLPVVLASIVTICG 2496
+ R +AF+++LRQDI+F+D + TG L + +T+ N+ V L ++ + T+
Sbjct: 855 RRARSQAFRSILRQDISFFDREENSTGALTSFLSTETKNLSGVSGVTLGTIIMTSTTLGA 914
Query: 2497 ALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIR 2676
A+ I GW+ G+ M Q R E + A +A IR
Sbjct: 915 AMIIALAIGWKLALVCISVVPILLACGFLRFYMLAQFQQRSKSAYEGSASYACEATSAIR 974
Query: 2677 TVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVN 2856
TV SL R++ Y + L++ +L ++A SQ+L+FF A F+ G +
Sbjct: 975 TVASLTREQDVWGVYHDQLQKQGRKSLISVLRSSLLYASSQALVFFCVALGFWYGGTLLG 1034
Query: 2857 QQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSG 3036
+ F I F Q G SF PD+ KA+ AA+ L + ID SD G
Sbjct: 1035 HHEYSIFRFFVCFSEILFGAQSAGTVFSFAPDMGKAKNAAAQFKKLFDSKPTIDIWSDEG 1094
Query: 3037 -IVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLER 3213
++ + G I R+V F YPTR + VL+G L +K G+ +ALVG SGCGKST + LLER
Sbjct: 1095 EKLESMEGEIEFRDVHFRYPTRPEQPVLRGLNLSVKPGQYIALVGPSGCGKSTTIALLER 1154
Query: 3214 FYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNR-NVTYQEI 3390
FY+ G + +DG +I LN++S R + +VSQEPTL+ TI ENI G ++ +V+ + +
Sbjct: 1155 FYDALAGGVFVDGKDITKLNVNSYRSFLSLVSQEPTLYQGTIKENILLGVDKDDVSEETL 1214
Query: 3391 VEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSA 3570
++ K ANI++F++ LP+G+DT VG KG LSGGQKQR+AIARAL+R P VLLLDEATSA
Sbjct: 1215 IKVCKDANIYDFVMSLPEGFDTVVGSKGGMLSGGQKQRVAIARALLRDPKVLLLDEATSA 1274
Query: 3571 LDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSE 3750
LD+ESEK+VQ ALDAA +GRT + +AHRLSTIQN+D+I + +GKIVE GTH ELIR
Sbjct: 1275 LDSESEKVVQAALDAAARGRTTIAVAHRLSTIQNADIIYVFDQGKIVESGTHHELIRNKG 1334
Query: 3751 IYQKFCETQRI 3783
Y + Q +
Sbjct: 1335 RYYELVNLQSL 1345
Score = 325 bits (832), Expect = 7e-87
Identities = 201/531 (37%), Positives = 292/531 (54%), Gaps = 12/531 (2%)
Frame = +1
Query: 2239 FVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRF 2418
FV +GI FV + S GE LT K+R + +LRQ++A++D L G G++ TR
Sbjct: 163 FVYLGIAEFVTVYVSTVGFIYTGEHLTQKIRENYLEAILRQNMAYFDKL--GAGEVTTRI 220
Query: 2419 ATDAPNVRYVFT-RLPVVLASIVTICGALGIGFYYGWQXXX--XXXXXXXXXXMGGYFEM 2589
D ++ + ++ + L + T A + + W+ MGG
Sbjct: 221 TADTNLIQDAISEKVGLTLTAFATFVTAFIVAYVKYWKLALICTSTIVALVMVMGGGSRF 280
Query: 2590 QMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAH 2769
+++ K + + G VA + + IR + Q++ Y +L E +K
Sbjct: 281 IVKYSK--KSIESYGAGGTVAEEVISSIRNATAFGTQDKLAKQYETHLAEAEKWGVKQQV 338
Query: 2770 TYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIP 2949
G + ++F Y F++GS FV + + V V +I +GN
Sbjct: 339 ILGMMIGGMFGIMFSNYGLGFWMGSRFVVGKEVNVGQVLTVLMSILIGSFSLGNVAPNGQ 398
Query: 2950 DVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTKVLQGF 3126
AA+ ++ I+ +P+D SD G ++ GNI RNV YP+R + V++
Sbjct: 399 AFTNGVAAAAKIYSTIDRRSPLDPYSDEGKVLDHFEGNIEFRNVKHIYPSRPEVTVMEDV 458
Query: 3127 TLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIV 3306
+L + AGKT ALVG SG GKST++GL+ERFY G +++DG +I+ LN+ LR+Q+ +V
Sbjct: 459 SLSMPAGKTTALVGPSGSGKSTVVGLVERFYLPVGGQVLLDGHDIQTLNLRWLRQQISLV 518
Query: 3307 SQEPTLFDCTIGENICYGT-------NRNVTYQEIVE-AAKMANIHNFILGLPDGYDTHV 3462
SQEP LF TI NI +G +E+VE AA+MAN H+FI+ LP+GYDT+V
Sbjct: 519 SQEPVLFSTTIFRNIEHGLIGTKFEHESKDKIRELVENAARMANAHDFIMALPEGYDTNV 578
Query: 3463 GEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLV 3642
G++G LSGGQKQRIAIARA+V P +LLLDEATSALDT+SE +VQ ALD A +GRT +V
Sbjct: 579 GQRGFLLSGGQKQRIAIARAIVSDPKILLLDEATSALDTKSEGVVQAALDKAAEGRTTIV 638
Query: 3643 IAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRIVESQ 3795
IAHRLSTI+ + I + GKI E+GTHDEL+ + Y K E QRI E +
Sbjct: 639 IAHRLSTIKTAHNIVAMVGGKIAEQGTHDELVDRKGTYYKLVEAQRINEEK 689
>gi|15234322|ref|NP_192091.1| multidrug resistance P-glycoprotein,
putative [Arabidopsis thaliana]
gi|25297452|pir||D85023 P-glycoprotein-like protein pgp3 [imported] -
Arabidopsis thaliana
gi|4558551|gb|AAD22644.1| P-glycoprotein-like protein [Arabidopsis
thaliana]
gi|7268566|emb|CAB80675.1| P-glycoprotein-like protein pgp3
[Arabidopsis thaliana]
Length = 1229
Score = 782 bits (2019), Expect = 0.0
Identities = 446/1220 (36%), Positives = 690/1220 (56%), Gaps = 9/1220 (0%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNP 285
Y +F ++ D+LL+I G++ A+ +G GFPL+ ++ G + + Q++ +V +
Sbjct: 11 YKLFSFSDSTDVLLMIVGSIGAIGNGVGFPLMTLLFGDLIDSIGQNQSNKDIVEI----- 65
Query: 286 EGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAIL 465
V K C+ ++ LG+ +++Q+AC+ ER ++R YLK IL
Sbjct: 66 --------------VSKVCLKFVYLGLGTLGAAFLQVACWMITGERQAARIRSLYLKTIL 111
Query: 466 RQQIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMT 642
RQ I +FD + TG + R++ D + E +G+K +Q+ A F+ G+ + F W +T
Sbjct: 112 RQDIGFFDVETSTGEVVGRMSGDTVLILEAMGEKVGKFIQLIATFVGGFVLAFVKGWLLT 171
Query: 643 LVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELD 822
LVM+ PL+ ++GA M + + EQ YA A + E+T SIRTV S G K+ +
Sbjct: 172 LVMLVSIPLLAIAGAAMPIIVTRASSREQAAYAKASTVVEQTLGSIRTVASFTGEKQAMK 231
Query: 823 RFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTV 1002
+ + + + + + MG+G+G + SYALA W+G +I+ + G + V
Sbjct: 232 SYREFINLAYRASVKQGFSMGLGLGVVFFVFFCSYALAIWFGGEMILKKG-YTGGEVVNV 290
Query: 1003 FFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISF 1182
V++ S SLG P L +F + AA + I P ID + L G ++++++G+I
Sbjct: 291 MVTVVASSMSLGQTTPCLTAFAAGKAAAYKMFETIERKPSIDAFDLNGKVLEDIRGEIEL 350
Query: 1183 KDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLID 1362
+DV F YP+R V G SL + +G ALVG SG GKS++++L++RFYDP+ G VLID
Sbjct: 351 RDVCFSYPARPMEEVFGGFSLLIPSGATAALVGESGSGKSSVISLIERFYDPSSGSVLID 410
Query: 1363 GVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIK 1542
GV+L+E + +R +IG+VSQEPVLF +I ENI G E+AT +++ A K+ANA +FI
Sbjct: 411 GVNLKEFQLKWIRGKIGLVSQEPVLFSSSIMENIGYGKENATVEEIQAAAKLANAANFID 470
Query: 1543 RLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALD 1722
+LP G T VGE G QLSGGQKQRIAIARA++K+P+ILLLDEATSALD E+ER VQ ALD
Sbjct: 471 KLPRGLETLVGEHGTQLSGGQKQRIAIARAILKDPRILLLDEATSALDAESERVVQEALD 530
Query: 1723 QAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSK-QGIFYDMTXXXXXXX 1899
+ RTT+IVAHRLST+RN D I V G IVE GSH EL+ +G + +
Sbjct: 531 RVMMSRTTVIVAHRLSTVRNADMIAVIHRGKIVEEGSHSELLKDHEGAYAQLIRLQKIKK 590
Query: 1900 X--XXEAGKDIED-TISESAHSHLXXXXXXXXXXXXXXXI-HQLAEEVEECKAPPTSMFK 2067
E+ ++ D +I+ + ++ + Q E+ ++ S+ +
Sbjct: 591 EPKRLESSNELRDRSINRGSSRNIRTRVHDDDSVSVLGLLGRQENTEISREQSRNVSITR 650
Query: 2068 IFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANVYFWCGMFVL 2247
I N + ++ P+F +++A++ + P M+ + FW +FVL
Sbjct: 651 IAALNKPETTILILGTLLGAVNGTIFPIFGILFAKVIEAFFKPPHDMKRDSRFWSMIFVL 710
Query: 2248 MGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATD 2427
+G+ + + G L ++R F+ ++ ++ ++DD + +G + +R + D
Sbjct: 711 LGVASLIVYPMHTYLFAVAGGRLIQRIRVMCFEKVVHMEVGWFDDPENSSGTIGSRLSAD 770
Query: 2428 APNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFG 2604
A ++ V L + + + L I F W+ + GY +++ G
Sbjct: 771 AALIKTLVGDSLSLSVKNAAAAVSGLIIAFTASWKLAVIILVMIPLIGINGYLQIKFIKG 830
Query: 2605 KQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAV 2784
EEA +VA+ AV IRTV S +E+ Y + + + +K G
Sbjct: 831 FTADAKAKYEEASQVANDAVGSIRTVASFCAEEKVMEMYKKRCEDTIKSGIKQGLISGVG 890
Query: 2785 FAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKA 2964
F S +++ +YA+ FY+G+ V DV++VF A++ I +SF PD KA
Sbjct: 891 FGISFFVLYSVYASCFYVGARLVKAGRTNFNDVFQVFLALTMTAIGISQASSFAPDSSKA 950
Query: 2965 RLAASLLFYLIEHPTPIDSLSDSGIV-KPITGNISIRNVFFNYPTRKDTKVLQGFTLDIK 3141
+ AA+ +F +I+ + IDS +SG+V + + G+I + ++ F Y TR D ++ + I+
Sbjct: 951 KGAAASIFGIIDGKSMIDSRDESGLVLENVKGDIELCHISFTYQTRPDVQIFRDLCFAIR 1010
Query: 3142 AGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPT 3321
AG+TVALVG SG GKST++ LL+RFY+ D G I +D ++ L + +R+Q+ +V QEP
Sbjct: 1011 AGQTVALVGESGSGKSTVISLLQRFYDPDSGHITLDRVELKKLQLKWVRQQMGLVGQEPV 1070
Query: 3322 LFDCTIGENICYGTNRNVTYQ-EIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQK 3498
LF+ TI NI YG + + EI+ AA++AN H FI + GYDT VGE+G QLSGGQK
Sbjct: 1071 LFNDTIRSNIAYGKGGDEASEAEIIAAAELANAHGFISSIQQGYDTVVGERGIQLSGGQK 1130
Query: 3499 QRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSD 3678
QR+AIARA+V+ P +LLLDEATSALD ESE++VQ+ALD RT +V+AHRLSTI+N+D
Sbjct: 1131 QRVAIARAIVKEPKILLLDEATSALDAESERVVQDALDRVMVNRTTVVVAHRLSTIKNAD 1190
Query: 3679 VIAIVSEGKIVEKGTHDELI 3738
VIA+V G IVEKGTH+ LI
Sbjct: 1191 VIAVVKNGVIVEKGTHETLI 1210
Score = 360 bits (924), Expect = 1e-97
Identities = 202/579 (34%), Positives = 326/579 (55%), Gaps = 4/579 (0%)
Frame = +1
Query: 145 LLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNS 324
+LI GT+ ++G FP+ I+ + F + + +
Sbjct: 661 ILILGTLLGAVNGTIFPIFGILFAKVIEAFFKPPH---------------------DMKR 699
Query: 325 EVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD--KQQ 498
+ + + +++LGV + F RL+ ++R + ++ ++ WFD +
Sbjct: 700 DSRFWSMIFVLLGVASLIVYPMHTYLFAVAGGRLIQRIRVMCFEKVVHMEVGWFDDPENS 759
Query: 499 TGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVL 678
+G + +RL+ D ++ +GD +L V+ AA ++G + F SW + ++++ PLI +
Sbjct: 760 SGTIGSRLSADAALIKTLVGDSLSLSVKNAAAAVSGLIIAFTASWKLAVIILVMIPLIGI 819
Query: 679 SGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQT 858
+G K + T + Y A +A + SIRTV S ++ ++ + E ++
Sbjct: 820 NGYLQIKFIKGFTADAKAKYEEASQVANDAVGSIRTVASFCAEEKVMEMYKKRCEDTIKS 879
Query: 859 GIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLG 1038
GI + G+G G S +YS YA F+ G+ L+ T + +F VF A+ + +
Sbjct: 880 GIKQGLISGVGFGISFFVLYSVYASCFYVGARLVKAGRT-NFNDVFQVFLALTMTAIGIS 938
Query: 1039 GALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKD 1218
A A+GAA+++ +I+ ID G++++N+KGDI + F Y +R D
Sbjct: 939 QASSFAPDSSKAKGAAASIFGIIDGKSMIDSRDESGLVLENVKGDIELCHISFTYQTRPD 998
Query: 1219 IHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSL 1398
+ + + + ++AG +ALVG SG GKST+++LLQRFYDP G + +D V+L+++ + +
Sbjct: 999 VQIFRDLCFAIRAGQTVALVGESGSGKSTVISLLQRFYDPDSGHITLDRVELKKLQLKWV 1058
Query: 1399 REQIGIVSQEPVLFDGTIYENIKMGN--EHATHDQVVEACKMANANDFIKRLPDGYGTRV 1572
R+Q+G+V QEPVLF+ TI NI G + A+ +++ A ++ANA+ FI + GY T V
Sbjct: 1059 RQQMGLVGQEPVLFNDTIRSNIAYGKGGDEASEAEIIAAAELANAHGFISSIQQGYDTVV 1118
Query: 1573 GEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTII 1752
GE+G+QLSGGQKQR+AIARA+VK PKILLLDEATSALD E+ER VQ ALD+ RTT++
Sbjct: 1119 GERGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERVVQDALDRVMVNRTTVV 1178
Query: 1753 VAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFY 1869
VAHRLSTI+N D I V K G IVE G+HE L++ +G Y
Sbjct: 1179 VAHRLSTIKNADVIAVVKNGVIVEKGTHETLINIEGGVY 1217
Score = 317 bits (813), Expect = 1e-84
Identities = 191/521 (36%), Positives = 281/521 (53%), Gaps = 3/521 (0%)
Frame = +1
Query: 2230 CGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLC 2409
C FV +G+ F C GE ++R K +LRQDI F+D + TG++
Sbjct: 70 CLKFVYLGLGTLGAAFLQVACWMITGERQAARIRSLYLKTILRQDIGFFD-VETSTGEVV 128
Query: 2410 TRFATDAPNVRYVF-TRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFE 2586
R + D + ++ + I T G + F GW + G
Sbjct: 129 GRMSGDTVLILEAMGEKVGKFIQLIATFVGGFVLAFVKGWLLTLVMLVSIPLLAIAGAAM 188
Query: 2587 MQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHA 2766
+ R+ +A V Q + IRTV S ++Q +Y E++ + ++K
Sbjct: 189 PIIVTRASSREQAAYAKASTVVEQTLGSIRTVASFTGEKQAMKSYREFINLAYRASVKQG 248
Query: 2767 HTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFI 2946
+ G + F YA A + G + ++ +V V + +G TT +
Sbjct: 249 FSMGLGLGVVFFVFFCSYALAIWFGGEMILKKGYTGGEVVNVMVTVVASSMSLGQTTPCL 308
Query: 2947 PDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTKVLQG 3123
+ AA +F IE ID+ +G +++ I G I +R+V F+YP R +V G
Sbjct: 309 TAFAAGKAAAYKMFETIERKPSIDAFDLNGKVLEDIRGEIELRDVCFSYPARPMEEVFGG 368
Query: 3124 FTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCI 3303
F+L I +G T ALVG SG GKS+++ L+ERFY+ G ++IDG N++ + +R ++ +
Sbjct: 369 FSLLIPSGATAALVGESGSGKSSVISLIERFYDPSSGSVLIDGVNLKEFQLKWIRGKIGL 428
Query: 3304 VSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQL 3483
VSQEP LF +I ENI YG N T +EI AAK+AN NFI LP G +T VGE GTQL
Sbjct: 429 VSQEPVLFSSSIMENIGYG-KENATVEEIQAAAKLANAANFIDKLPRGLETLVGEHGTQL 487
Query: 3484 SGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLST 3663
SGGQKQRIAIARA+++ P +LLLDEATSALD ESE++VQEALD RT +++AHRLST
Sbjct: 488 SGGQKQRIAIARAILKDPRILLLDEATSALDAESERVVQEALDRVMMSRTTVIVAHRLST 547
Query: 3664 IQNSDVIAIVSEGKIVEKGTHDELIRKSE-IYQKFCETQRI 3783
++N+D+IA++ GKIVE+G+H EL++ E Y + Q+I
Sbjct: 548 VRNADMIAVIHRGKIVEEGSHSELLKDHEGAYAQLIRLQKI 588
>gi|17136662|ref|NP_476831.1| CG10181-PA [Drosophila melanogaster]
gi|17380460|sp|Q00748|MDR5_DROME Multidrug resistance protein homolog
65 (P-glycoprotein 65)
gi|7295351|gb|AAF50669.1| CG10181-PA [Drosophila melanogaster]
gi|7767568|gb|AAF69146.1| P-glycoprotein [Drosophila melanogaster]
gi|7767570|gb|AAF69147.1| P-glycoprotein [Drosophila melanogaster]
Length = 1302
Score = 781 bits (2018), Expect = 0.0
Identities = 448/1188 (37%), Positives = 669/1188 (55%), Gaps = 38/1188 (3%)
Frame = +1
Query: 331 VKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNL 510
+ Y I + V+MF + + F A R V ++R +++RQ I W D N
Sbjct: 118 ISYGILLTIASVVMFISGIFSVDVFNMVALRQVTRMRIKLFSSVIRQDIGWHDLASKQNF 177
Query: 511 TARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAK 690
T + DD+E++R+G+ +K V + F+ + F Y W +TL + + PL++L
Sbjct: 178 TQSMVDDVEKIRDGISEKVGHFVYLVVGFIITVAISFSYGWKLTLAVSSYIPLVILLNYY 237
Query: 691 MSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVK 870
++K T EQE+YA AG +AEE SSIRTV S G K E+ R+ N L R+ K
Sbjct: 238 VAKFQGKLTAREQESYAGAGNLAEEILSSIRTVVSFGGEKSEVQRYENFLVPARKASQWK 297
Query: 871 YCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDR-----GLIFTVFFAVLSGSTSL 1035
+ G+ +Y S A AFWYG LII+D + ++ FF ++ G+ ++
Sbjct: 298 GAFSGLSDAVLKSMLYLSCAGAFWYGVNLIIDDRNVENKEYTPAILMIAFFGIIVGADNI 357
Query: 1036 GGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVD-NMKGDISFKDVHFRYPSR 1212
P L SF TARG A+ + +VI+ KIDP S +G L++ ++GD+ F+DV FRYPSR
Sbjct: 358 ARTAPFLESFATARGCATNLFKVIDLTSKIDPLSTDGKLLNYGLRGDVEFQDVFFRYPSR 417
Query: 1213 KDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVH 1392
++ V +G+++ ++AG +ALVGSSGCGKST V LLQRFYDP G VL+D +D+R+ N+
Sbjct: 418 PEVIVHRGLNIRIRAGQTVALVGSSGCGKSTCVQLLQRFYDPVFGSVLLDDLDIRKYNIQ 477
Query: 1393 SLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRV 1572
LR I +V QEPVLF GTI +NI G AT ++ A A A++FI LP+ Y + +
Sbjct: 478 WLRSNIAVVGQEPVLFLGTIAQNISYGKPGATQKEIEAAATQAGAHEFITNLPESYRSMI 537
Query: 1573 GEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTII 1752
GE+G QLSGGQKQRIAIARAL++NPKILLLDEATSALD ++E++VQ ALD A GRTTI+
Sbjct: 538 GERGSQLSGGQKQRIAIARALIQNPKILLLDEATSALDYQSEKQVQQALDLASKGRTTIV 597
Query: 1753 VAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXX-XXXEAGKDIE 1929
V+HRLS IR D+I G ++E GSH++LM+ +G +Y+M E IE
Sbjct: 598 VSHRLSAIRGADKIVFIHDGKVLEEGSHDDLMALEGAYYNMVRAGDINMPDEVEKEDSIE 657
Query: 1930 DTISES-AHSHLXXXXXXXXXXXXXXXIHQLAEEV----------EECKAPP------TS 2058
DT +S A Q E + + +APP +
Sbjct: 658 DTKQKSLALFEKSFETSPLNFEKGQKNSVQFEEPIIKALIKDTNAQSAEAPPEKPNFFRT 717
Query: 2059 MFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSL--PADQMQANVYFWC 2232
+I + + + + P FA+++ E + + P D ++
Sbjct: 718 FSRILQLAKQEWCYLILGTISAVAVGFLYPAFAVIFGEFYAALAEKDPEDALRRTAVL-- 775
Query: 2233 GMFVLMGITFFVGF--FTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKL 2406
+ +G+ F G F G LT ++R F ++ Q++ ++DD + G L
Sbjct: 776 -SWACLGLAFLTGLVCFLQTYLFNYAGIWLTTRMRAMTFNAMVNQEVGWFDDENNSVGAL 834
Query: 2407 CTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYF 2583
R + +A +++ + L ++ ++ ++ + YY W+
Sbjct: 835 SARLSGEAVDIQGAIGYPLSGMIQALSNFISSVSVAMYYNWKLALLCLANCPIIVGSVIL 894
Query: 2584 EMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKH 2763
E +M +R+ Q++EEA ++A++++ +IRTV L R+ Y E ++ +
Sbjct: 895 EAKMMSNAVVREKQVIEEACRIATESITNIRTVAGLRREADVIREYTEEIQRVEVLIRQK 954
Query: 2764 AHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSF 2943
G + + Q+ FF YA A G + V++ + D+ +V + + M+ + +F
Sbjct: 955 LRWRGVLNSTMQASAFFAYAVALCYGGVLVSEGQLPFQDIIKVSETLLYGSMMLAQSLAF 1014
Query: 2944 IPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVK-------PITGNISIRNVFFNYPTRK 3102
P A +A LF +++ I S G +K + + R + F YPTR
Sbjct: 1015 TPAFSAALIAGHRLFQILDRKPKIQ--SPMGTIKNTLAKQLNLFEGVRYRGIQFRYPTRP 1072
Query: 3103 DTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIR-NLNIS 3279
D K+L G L++ G+TVALVGHSGCGKST + LL+R+Y+ D+G I ID D+I+ +L +
Sbjct: 1073 DAKILNGLDLEVLKGQTVALVGHSGCGKSTCVQLLQRYYDPDEGTIHIDHDDIQHDLTLD 1132
Query: 3280 SLREQVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDT 3456
+R ++ IVSQEPTLF+ +I ENI YG N R+V+ EI+ AAK AN H+FI+ LP+GYDT
Sbjct: 1133 GVRTKLGIVSQEPTLFERSIAENIAYGDNRRSVSMVEIIAAAKSANAHSFIISLPNGYDT 1192
Query: 3457 HVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTC 3636
+G +GTQLSGGQKQRIAIARALVR+P +LLLDEATSALD +SE++VQ+ALD A GRTC
Sbjct: 1193 RMGARGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDLQSEQLVQQALDTACSGRTC 1252
Query: 3637 LVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQR 3780
+VIAHRLST+QN+DVI ++ G++VE+G H +LI + IY K +TQ+
Sbjct: 1253 IVIAHRLSTVQNADVICVIQNGQVVEQGNHMQLISQGGIYAKLHKTQK 1300
Score = 322 bits (826), Expect = 3e-86
Identities = 207/585 (35%), Positives = 325/585 (55%), Gaps = 12/585 (2%)
Frame = +1
Query: 148 LITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSE 327
LI GT++AV G +P A++ G +F + +PE + +
Sbjct: 732 LILGTISAVAVGFLYPAFAVIFG------------EFYAALAEKDPEDALR------RTA 773
Query: 328 VVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQT-- 501
V+ + L L L ++Q F L ++R A++ Q++ WFD +
Sbjct: 774 VLSWAC--LGLAFLTGLVCFLQTYLFNYAGIWLTTRMRAMTFNAMVNQEVGWFDDENNSV 831
Query: 502 GNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLS 681
G L+ARL+ + ++ +G + ++Q + F++ V +Y+W + L+ + P+IV S
Sbjct: 832 GALSARLSGEAVDIQGAIGYPLSGMIQALSNFISSVSVAMYYNWKLALLCLANCPIIVGS 891
Query: 682 GAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTG 861
+K M+ E++ A IA E+ ++IRTV L +RE D E ++
Sbjct: 892 VILEAKMMSNAVVREKQVIEEACRIATESITNIRTVAGL---RREADVIREYTEEIQRVE 948
Query: 862 IV---KYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTS 1032
++ K + G+ + +YA+A YG L+ + +I V +L GS
Sbjct: 949 VLIRQKLRWRGVLNSTMQASAFFAYAVALCYGGVLVSEGQLPFQDII-KVSETLLYGSMM 1007
Query: 1033 LGGALPHLASFGTARGAASTVLRVINSHPKIDPY--SLEGILVD--NMKGDISFKDVHFR 1200
L +L +F A A + ++++ PKI +++ L N+ + ++ + FR
Sbjct: 1008 LAQSLAFTPAFSAALIAGHRLFQILDRKPKIQSPMGTIKNTLAKQLNLFEGVRYRGIQFR 1067
Query: 1201 YPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLR- 1377
YP+R D +L G+ LE+ G +ALVG SGCGKST V LLQR+YDP +G + ID D++
Sbjct: 1068 YPTRPDAKILNGLDLEVLKGQTVALVGHSGCGKSTCVQLLQRYYDPDEGTIHIDHDDIQH 1127
Query: 1378 EVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHD--QVVEACKMANANDFIKRLP 1551
++ + +R ++GIVSQEP LF+ +I ENI G+ + +++ A K ANA+ FI LP
Sbjct: 1128 DLTLDGVRTKLGIVSQEPTLFERSIAENIAYGDNRRSVSMVEIIAAAKSANAHSFIISLP 1187
Query: 1552 DGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQ 1731
+GY TR+G +G QLSGGQKQRIAIARALV+NPKILLLDEATSALD ++E+ VQ ALD A
Sbjct: 1188 NGYDTRMGARGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDLQSEQLVQQALDTAC 1247
Query: 1732 AGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIF 1866
+GRT I++AHRLST++N D I V + G +VE G+H +L+S+ GI+
Sbjct: 1248 SGRTCIVIAHRLSTVQNADVICVIQNGQVVEQGNHMQLISQGGIY 1292
Score = 289 bits (740), Expect = 3e-76
Identities = 194/624 (31%), Positives = 314/624 (50%), Gaps = 44/624 (7%)
Frame = +1
Query: 2017 LAEEVEECKAPPTSMFKIFKFNG-DKVGWXXXXXXXXXXXXSVTPVFALVYAEIF----- 2178
+AE +E + P + K+F+F+ ++GW P ++Y+E
Sbjct: 21 MAEGLEPTE--PIAFLKLFRFSTYGEIGWLFFGFIMCCIKALTLPAVVIIYSEFTSMLVD 78
Query: 2179 ---------NVYSLP----------ADQMQANVYFWCG------MFVLMGITFFVGFFTS 2283
NV++LP A + + N + + + + F+ S
Sbjct: 79 RAMQFGTSSNVHALPLFGGGKTLTNASREENNEALYDDSISYGILLTIASVVMFISGIFS 138
Query: 2284 ANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVFTR-- 2457
+ ++R + F +++RQDI ++D D +R +
Sbjct: 139 VDVFNMVALRQVTRMRIKLFSSVIRQDIGWHD--LASKQNFTQSMVDDVEKIRDGISEKV 196
Query: 2458 ---LPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQL 2628
+ +V+ I+T+ I F YGW+ + Y+ + + R+ +
Sbjct: 197 GHFVYLVVGFIITVA----ISFSYGWKLTLAVSSYIPLVILLNYYVAKFQGKLTAREQES 252
Query: 2629 LEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLI 2808
AG +A + + IRTV S ++ Y +L + G A +S++
Sbjct: 253 YAGAGNLAEEILSSIRTVVSFGGEKSEVQRYENFLVPARKASQWKGAFSGLSDAVLKSML 312
Query: 2809 FFMYAAAFYLG-SIFVNQQAMQPIDVYRVFFAISFCGQMIG-----NTTSFIPDVVKARL 2970
+ A AF+ G ++ ++ + ++ + I+F G ++G T F+ AR
Sbjct: 313 YLSCAGAFWYGVNLIIDDRNVENKEYTPAILMIAFFGIIVGADNIARTAPFLESFATARG 372
Query: 2971 AASLLFYLIEHPTPIDSLSDSG--IVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKA 3144
A+ LF +I+ + ID LS G + + G++ ++VFF YP+R + V +G + I+A
Sbjct: 373 CATNLFKVIDLTSKIDPLSTDGKLLNYGLRGDVEFQDVFFRYPSRPEVIVHRGLNIRIRA 432
Query: 3145 GKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTL 3324
G+TVALVG SGCGKST + LL+RFY+ G +++D +IR NI LR + +V QEP L
Sbjct: 433 GQTVALVGSSGCGKSTCVQLLQRFYDPVFGSVLLDDLDIRKYNIQWLRSNIAVVGQEPVL 492
Query: 3325 FDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQR 3504
F TI +NI YG T +EI AA A H FI LP+ Y + +GE+G+QLSGGQKQR
Sbjct: 493 FLGTIAQNISYG-KPGATQKEIEAAATQAGAHEFITNLPESYRSMIGERGSQLSGGQKQR 551
Query: 3505 IAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVI 3684
IAIARAL+++P +LLLDEATSALD +SEK VQ+ALD A +GRT +V++HRLS I+ +D I
Sbjct: 552 IAIARALIQNPKILLLDEATSALDYQSEKQVQQALDLASKGRTTIVVSHRLSAIRGADKI 611
Query: 3685 AIVSEGKIVEKGTHDELIRKSEIY 3756
+ +GK++E+G+HD+L+ Y
Sbjct: 612 VFIHDGKVLEEGSHDDLMALEGAY 635
>gi|25455873|pir||T52319 P-glycoprotein-like protein pgp3 [imported] -
Arabidopsis thaliana
gi|2739309|emb|CAA75922.1| P-glycoprotein-like protein [Arabidopsis
thaliana]
Length = 1229
Score = 781 bits (2016), Expect = 0.0
Identities = 445/1220 (36%), Positives = 690/1220 (56%), Gaps = 9/1220 (0%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNP 285
Y +F ++ D+LL+I G++ A+ +G GFPL+ ++ G + + Q++ +V +
Sbjct: 11 YKLFSFSDSTDVLLMIVGSIGAIGNGVGFPLMTLLFGDLIDSIGQNQSNKDIVEI----- 65
Query: 286 EGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAIL 465
V K C+ ++ LG+ +++++AC+ ER ++R YLK IL
Sbjct: 66 --------------VSKVCLKFVYLGLGTLGAAFLEVACWMITGERQAARIRSLYLKTIL 111
Query: 466 RQQIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMT 642
RQ I +FD + TG + R++ D + E +G+K +Q+ A F+ G+ + F W +T
Sbjct: 112 RQDIGFFDVETSTGEVVGRMSGDTVLILEAMGEKVGKFIQLIATFVGGFVLAFVKGWLLT 171
Query: 643 LVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELD 822
LVM+ PL+ ++GA M + + EQ YA A + E+T SIRTV S G K+ +
Sbjct: 172 LVMLVSIPLLAIAGAAMPIIVTRASSREQAAYAKASTVVEQTLGSIRTVASFTGEKQAMK 231
Query: 823 RFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTV 1002
+ + + + + + MG+G+G + SYALA W+G +I+ + G + V
Sbjct: 232 SYREFINLAYRASVKQGFSMGLGLGVVFFVFFCSYALAIWFGGEMILKKG-YTGGEVVNV 290
Query: 1003 FFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISF 1182
V++ S SLG P L +F + AA + I P ID + L G ++++++G+I
Sbjct: 291 MVTVVASSMSLGQTTPCLTAFAAGKAAAYKMFETIERKPSIDAFDLNGKVLEDIRGEIEL 350
Query: 1183 KDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLID 1362
+DV F YP+R V G SL + +G ALVG SG GKS++++L++RFYDP+ G VLID
Sbjct: 351 RDVCFSYPARPMEEVFGGFSLLIPSGATAALVGESGSGKSSVISLIERFYDPSSGSVLID 410
Query: 1363 GVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIK 1542
GV+L+E + +R +IG+VSQEPVLF +I ENI G E+AT +++ A K+ANA +FI
Sbjct: 411 GVNLKEFQLKWIRGKIGLVSQEPVLFSSSIMENIGYGKENATVEEIQAAAKLANAANFID 470
Query: 1543 RLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALD 1722
+LP G T VGE G QLSGGQKQRIAIARA++K+P+ILLLDEATSALD E+ER VQ ALD
Sbjct: 471 KLPRGLETLVGEHGTQLSGGQKQRIAIARAILKDPRILLLDEATSALDAESERVVQEALD 530
Query: 1723 QAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSK-QGIFYDMTXXXXXXX 1899
+ RTT+IVAHRLST+RN D I V G IVE GSH EL+ +G + +
Sbjct: 531 RVMMSRTTVIVAHRLSTVRNADMIAVIHRGKIVEEGSHSELLKDHEGAYAQLIRLQKIKK 590
Query: 1900 X--XXEAGKDIED-TISESAHSHLXXXXXXXXXXXXXXXI-HQLAEEVEECKAPPTSMFK 2067
E+ ++ D +I+ + ++ + Q E+ ++ S+ +
Sbjct: 591 EPKRLESSNELRDRSINRGSSRNIRTRVHDDDSVSVLGLLGRQENTEISREQSRNVSITR 650
Query: 2068 IFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANVYFWCGMFVL 2247
I N + ++ P+F +++A++ + P M+ + FW +FVL
Sbjct: 651 IAALNKPETTILILGTLLGAVNGTIFPIFGILFAKVIEAFFKPPHDMKRDSRFWSMIFVL 710
Query: 2248 MGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATD 2427
+G+ + + G L ++R F+ ++ ++ ++DD + +G + +R + D
Sbjct: 711 LGVASLIVYPMHTYLFAVAGGRLIQRIRVMCFEKVVHMEVGWFDDPENSSGTIGSRLSAD 770
Query: 2428 APNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFG 2604
A ++ V L + + + L I F W+ + GY +++ G
Sbjct: 771 AALIKTLVGDSLSLSVKNAAAAVSGLIIAFTASWKLAVIILVMIPLIGINGYLQIKFIKG 830
Query: 2605 KQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAV 2784
EEA +VA+ AV IRTV S +E+ Y + + + +K G
Sbjct: 831 FTADAKAKYEEASQVANDAVGSIRTVASFCAEEKVMEMYKKRCEDTIKSGIKQGLISGVG 890
Query: 2785 FAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKA 2964
F S +++ +YA+ FY+G+ V DV++VF A++ I +SF PD KA
Sbjct: 891 FGISFFVLYSVYASCFYVGARLVKAGRTNFNDVFQVFLALTMTAIGISQASSFAPDSSKA 950
Query: 2965 RLAASLLFYLIEHPTPIDSLSDSGIV-KPITGNISIRNVFFNYPTRKDTKVLQGFTLDIK 3141
+ AA+ +F +I+ + IDS +SG+V + + G+I + ++ F Y TR D ++ + I+
Sbjct: 951 KGAAASIFGIIDGKSMIDSRDESGLVLENVKGDIELCHISFTYQTRPDVQIFRDLCFAIR 1010
Query: 3142 AGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPT 3321
AG+TVALVG SG GKST++ LL+RFY+ D G I +D ++ L + +R+Q+ +V QEP
Sbjct: 1011 AGQTVALVGESGSGKSTVISLLQRFYDPDSGHITLDRVELKKLQLKWVRQQMGLVGQEPV 1070
Query: 3322 LFDCTIGENICYGTNRNVTYQ-EIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQK 3498
LF+ TI NI YG + + EI+ AA++AN H FI + GYDT VGE+G QLSGGQK
Sbjct: 1071 LFNDTIRSNIAYGKGGDEASEAEIIAAAELANAHGFISSIQQGYDTVVGERGIQLSGGQK 1130
Query: 3499 QRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSD 3678
QR+AIARA+V+ P +LLLDEATSALD ESE++VQ+ALD RT +V+AHRLSTI+N+D
Sbjct: 1131 QRVAIARAIVKEPKILLLDEATSALDAESERVVQDALDRVMVNRTTVVVAHRLSTIKNAD 1190
Query: 3679 VIAIVSEGKIVEKGTHDELI 3738
VIA+V G IVEKGTH+ LI
Sbjct: 1191 VIAVVKNGVIVEKGTHETLI 1210
Score = 360 bits (924), Expect = 1e-97
Identities = 202/579 (34%), Positives = 326/579 (55%), Gaps = 4/579 (0%)
Frame = +1
Query: 145 LLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNS 324
+LI GT+ ++G FP+ I+ + F + + +
Sbjct: 661 ILILGTLLGAVNGTIFPIFGILFAKVIEAFFKPPH---------------------DMKR 699
Query: 325 EVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD--KQQ 498
+ + + +++LGV + F RL+ ++R + ++ ++ WFD +
Sbjct: 700 DSRFWSMIFVLLGVASLIVYPMHTYLFAVAGGRLIQRIRVMCFEKVVHMEVGWFDDPENS 759
Query: 499 TGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVL 678
+G + +RL+ D ++ +GD +L V+ AA ++G + F SW + ++++ PLI +
Sbjct: 760 SGTIGSRLSADAALIKTLVGDSLSLSVKNAAAAVSGLIIAFTASWKLAVIILVMIPLIGI 819
Query: 679 SGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQT 858
+G K + T + Y A +A + SIRTV S ++ ++ + E ++
Sbjct: 820 NGYLQIKFIKGFTADAKAKYEEASQVANDAVGSIRTVASFCAEEKVMEMYKKRCEDTIKS 879
Query: 859 GIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLG 1038
GI + G+G G S +YS YA F+ G+ L+ T + +F VF A+ + +
Sbjct: 880 GIKQGLISGVGFGISFFVLYSVYASCFYVGARLVKAGRT-NFNDVFQVFLALTMTAIGIS 938
Query: 1039 GALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKD 1218
A A+GAA+++ +I+ ID G++++N+KGDI + F Y +R D
Sbjct: 939 QASSFAPDSSKAKGAAASIFGIIDGKSMIDSRDESGLVLENVKGDIELCHISFTYQTRPD 998
Query: 1219 IHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSL 1398
+ + + + ++AG +ALVG SG GKST+++LLQRFYDP G + +D V+L+++ + +
Sbjct: 999 VQIFRDLCFAIRAGQTVALVGESGSGKSTVISLLQRFYDPDSGHITLDRVELKKLQLKWV 1058
Query: 1399 REQIGIVSQEPVLFDGTIYENIKMGN--EHATHDQVVEACKMANANDFIKRLPDGYGTRV 1572
R+Q+G+V QEPVLF+ TI NI G + A+ +++ A ++ANA+ FI + GY T V
Sbjct: 1059 RQQMGLVGQEPVLFNDTIRSNIAYGKGGDEASEAEIIAAAELANAHGFISSIQQGYDTVV 1118
Query: 1573 GEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTII 1752
GE+G+QLSGGQKQR+AIARA+VK PKILLLDEATSALD E+ER VQ ALD+ RTT++
Sbjct: 1119 GERGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERVVQDALDRVMVNRTTVV 1178
Query: 1753 VAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFY 1869
VAHRLSTI+N D I V K G IVE G+HE L++ +G Y
Sbjct: 1179 VAHRLSTIKNADVIAVVKNGVIVEKGTHETLINIEGGVY 1217
Score = 317 bits (813), Expect = 1e-84
Identities = 191/521 (36%), Positives = 281/521 (53%), Gaps = 3/521 (0%)
Frame = +1
Query: 2230 CGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLC 2409
C FV +G+ F C GE ++R K +LRQDI F+D + TG++
Sbjct: 70 CLKFVYLGLGTLGAAFLEVACWMITGERQAARIRSLYLKTILRQDIGFFD-VETSTGEVV 128
Query: 2410 TRFATDAPNVRYVF-TRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFE 2586
R + D + ++ + I T G + F GW + G
Sbjct: 129 GRMSGDTVLILEAMGEKVGKFIQLIATFVGGFVLAFVKGWLLTLVMLVSIPLLAIAGAAM 188
Query: 2587 MQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHA 2766
+ R+ +A V Q + IRTV S ++Q +Y E++ + ++K
Sbjct: 189 PIIVTRASSREQAAYAKASTVVEQTLGSIRTVASFTGEKQAMKSYREFINLAYRASVKQG 248
Query: 2767 HTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFI 2946
+ G + F YA A + G + ++ +V V + +G TT +
Sbjct: 249 FSMGLGLGVVFFVFFCSYALAIWFGGEMILKKGYTGGEVVNVMVTVVASSMSLGQTTPCL 308
Query: 2947 PDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTKVLQG 3123
+ AA +F IE ID+ +G +++ I G I +R+V F+YP R +V G
Sbjct: 309 TAFAAGKAAAYKMFETIERKPSIDAFDLNGKVLEDIRGEIELRDVCFSYPARPMEEVFGG 368
Query: 3124 FTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCI 3303
F+L I +G T ALVG SG GKS+++ L+ERFY+ G ++IDG N++ + +R ++ +
Sbjct: 369 FSLLIPSGATAALVGESGSGKSSVISLIERFYDPSSGSVLIDGVNLKEFQLKWIRGKIGL 428
Query: 3304 VSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQL 3483
VSQEP LF +I ENI YG N T +EI AAK+AN NFI LP G +T VGE GTQL
Sbjct: 429 VSQEPVLFSSSIMENIGYG-KENATVEEIQAAAKLANAANFIDKLPRGLETLVGEHGTQL 487
Query: 3484 SGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLST 3663
SGGQKQRIAIARA+++ P +LLLDEATSALD ESE++VQEALD RT +++AHRLST
Sbjct: 488 SGGQKQRIAIARAILKDPRILLLDEATSALDAESERVVQEALDRVMMSRTTVIVAHRLST 547
Query: 3664 IQNSDVIAIVSEGKIVEKGTHDELIRKSE-IYQKFCETQRI 3783
++N+D+IA++ GKIVE+G+H EL++ E Y + Q+I
Sbjct: 548 VRNADMIAVIHRGKIVEEGSHSELLKDHEGAYAQLIRLQKI 588
>gi|11346278|pir||T43261 multidrug resistance protein 1 - fungus
(Filobasidium floriforme)
gi|2668553|gb|AAC49889.1| multidrug resistance protein 1
[Filobasidiella neoformans]
gi|2668555|gb|AAC49890.1| multidrug resistance protein 1
[Filobasidiella neoformans]
Length = 1408
Score = 781 bits (2016), Expect = 0.0
Identities = 476/1271 (37%), Positives = 703/1271 (54%), Gaps = 45/1271 (3%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNP 285
+ +F + ++++ ++ G V AV G+ PL+ ++ G +TT F +++ V + ++
Sbjct: 142 FALFRFAAPLEIIAMVLGLVLAVAAGSCQPLMTLIFGRLTTSF-----TNYAVIANQISQ 196
Query: 286 EGLVP-------ISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQ 444
GL P + D+ ++ +Y + +G+ MF +++ + + E ++R+
Sbjct: 197 GGLTPETSAALQAAKDDLKTQSGHNALYLMAIGIGMFLATWLYMFIWNVTGELNSKRIRE 256
Query: 445 NYLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFF 624
YL A+LRQ+I +FD G + R+ D V+EG +K AL+ Q F+ G+ + F
Sbjct: 257 RYLAAVLRQEIAYFDDLGAGEVATRIQTDCHLVQEGTSEKVALVFQYAGTFVCGFVLAFV 316
Query: 625 YSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNG 804
S + ++ P+I+L G M +MA + A AG++AEE SIRTV +
Sbjct: 317 RSPRLAGALVSILPVIMLCGGIMMTAMAKYGTAALDHIAKAGSLAEEVIGSIRTVQAFGK 376
Query: 805 HKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDR 984
K D+F + +E + G + G G+ +Y++YALAF+YG L+ N D
Sbjct: 377 EKILGDKFADHIEQSKIVGRKGSIFEGFGLSIMFFVIYAAYALAFFYGGILVSNGQA-DS 435
Query: 985 GLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNM 1164
G++ VF ++L GS S+ P LA+ ARGAA+ + I+ P ID S EG D +
Sbjct: 436 GIVINVFMSILIGSFSMAMLAPELAAVTKARGAAAKLFATIDRVPAIDSASEEGFKPDGL 495
Query: 1165 KGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTK 1344
+G+ISF++V F YPSR I +LKG + +AG ALVG+SG GKST+V+L++RFYDP
Sbjct: 496 RGEISFENVKFHYPSRPSIPILKGFTTTFEAGKTFALVGASGSGKSTVVSLIERFYDPVS 555
Query: 1345 GRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMG-----NEHATHDQ---- 1497
G V +DG D+R +N++ LR+QIG+VSQEP LF T+ N++ G E+A+ ++
Sbjct: 556 GVVKLDGRDIRSLNLNWLRQQIGLVSQEPTLFGTTVRGNVEHGLIGSRYENASLEEKFEL 615
Query: 1498 VVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATS 1677
V +AC ANA++FI +LP GY T VGE+G+ LSGGQKQR+AIARA+V +P+ILLLDEATS
Sbjct: 616 VKKACVDANAHNFIMKLPQGYDTMVGERGMLLSGGQKQRVAIARAIVSDPRILLLDEATS 675
Query: 1678 ALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQ 1857
ALDT++E VQ ALD+A GRTTI +AHRLSTIR+ DRI+V G ++E GSH +L++ +
Sbjct: 676 ALDTQSEGIVQDALDKASRGRTTITIAHRLSTIRDADRIYVMGGGEVLEQGSHNDLLANE 735
Query: 1858 G-----IFYDMTXXXXXXXXXXEAGKDIED------------TISESAHSHLXXXXXXXX 1986
+ + + DIED + H
Sbjct: 736 NGPYAQLVNNQKLAQEAAAEALQVDDDIEDPDDAVFIGGSSPMQEKDKQLHRAVTGRSLA 795
Query: 1987 XXXXXXXIHQLAEEVEECKAPPTSM---FKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFA 2157
+ AEEV P+S ++ + N V P A
Sbjct: 796 SIAMDDIQAKRAEEVAGEDKIPSSFGLYARLLRMNSADKFIYIIAFIAAICAGMVYPSLA 855
Query: 2158 LVYAEIFNVYSL--PADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLR 2331
+++ + + + + PA+ A F+ FV FF SA R G L LR
Sbjct: 856 ILFGKALSDFEIQDPAELRHALSRSALWYFITALAAAFVIFFQSAG-FSRAGWDLNGVLR 914
Query: 2332 FEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVF-TRLPVVLASIVTICGALGI 2508
+ F LR DI ++D+ R+ TG + + A V+ +F L V+ S T+ G I
Sbjct: 915 KKLFTATLRHDIEWFDEERNSTGAVTSNLADQPQKVQGLFGPTLGTVVQSCATLIGGCII 974
Query: 2509 GFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHS 2688
G YG GGY +++ K R +L + +AS+A ++TV S
Sbjct: 975 GLCYGPLLALIGIACIPILVSGGYIRLKVVVLKDQRMKKLHAASAHLASEAAGAVKTVAS 1034
Query: 2689 LNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAM 2868
L R++ Y E L+ P N + + +FA SQ L F + A FY+G++++
Sbjct: 1035 LTREKDVRRIYSEALKAPMKLNFRTSIKSQCLFAASQGLTFCIIALVFYIGALWIIDAKY 1094
Query: 2869 QPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIV-- 3042
Y V +I F GN +F+PD KA +A+ +F I++ I++ S+ G V
Sbjct: 1095 STASFYTVLNSIVFASIQAGNVFTFVPDASKANSSAASIFRSIDNEPAINAESNEGKVLD 1154
Query: 3043 -KPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFY 3219
K + G++ I V F YPTR +VL+ T+D+ AG VALVG SGCGKST + +LERFY
Sbjct: 1155 HKHVVGHVRIEGVHFRYPTRPGVRVLRNLTIDVPAGTYVALVGPSGCGKSTTIQMLERFY 1214
Query: 3220 NQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNR---NVTYQEI 3390
+ G + +DG +I+ LN++S R Q+ +VSQEPTL+ TI NI G N+ VT EI
Sbjct: 1215 DPLAGRVTLDGIDIKELNLASYRSQISLVSQEPTLYAGTIRFNILLGANKPIEEVTQDEI 1274
Query: 3391 VEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSA 3570
A K ANI++FI+ LPDG+DT VG KG+QLSGGQKQRIAIARAL+R+P VLLLDEATSA
Sbjct: 1275 DAACKDANIYDFIVSLPDGFDTEVGGKGSQLSGGQKQRIAIARALIRNPKVLLLDEATSA 1334
Query: 3571 LDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSE 3750
LD++SEK+VQEALD A +GRT + IAHRLS+IQ+SD I SEG++ E GTH EL+ K
Sbjct: 1335 LDSQSEKVVQEALDKAAKGRTTIAIAHRLSSIQHSDRIYYFSEGRVAEHGTHQELLAKKG 1394
Query: 3751 IYQKFCETQRI 3783
Y + + Q +
Sbjct: 1395 GYYELVQMQNL 1405
Score = 304 bits (779), Expect = 9e-81
Identities = 217/643 (33%), Positives = 330/643 (50%), Gaps = 54/643 (8%)
Frame = +1
Query: 2023 EEVEECKAPPTSMFKIFKFNGD-KVGWXXXXXXXXXXXXSVTPVFALVYAEI---FNVYS 2190
+E E PP S F +F+F ++ S P+ L++ + F Y+
Sbjct: 129 KEKEASVLPPVSFFALFRFAAPLEIIAMVLGLVLAVAAGSCQPLMTLIFGRLTTSFTNYA 188
Query: 2191 LPADQMQAN----------------------------VYFWCGMFVLMGITFFVGFFTSA 2286
+ A+Q+ + GMF+ + F+ T
Sbjct: 189 VIANQISQGGLTPETSAALQAAKDDLKTQSGHNALYLMAIGIGMFLATWLYMFIWNVT-- 246
Query: 2287 NCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVFTRLPV 2466
GE + ++R +LRQ+IA++DDL G G++ TR TD V+ +
Sbjct: 247 ------GELNSKRIRERYLAAVLRQEIAYFDDL--GAGEVATRIQTDCHLVQEGTSE--- 295
Query: 2467 VLASIVTICGALGIGFYYGWQXXXXXXXXXXX-----XXMGGYFEMQM-RFGKQIRDTQL 2628
+A + G GF + GG M ++G D
Sbjct: 296 KVALVFQYAGTFVCGFVLAFVRSPRLAGALVSILPVIMLCGGIMMTAMAKYGTAALDH-- 353
Query: 2629 LEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVF-AFSQSL 2805
+ +AG +A + + IRTV + +++ + +++ + K G++F F S+
Sbjct: 354 IAKAGSLAEEVIGSIRTVQAFGKEKILGDKFADHIEQS-----KIVGRKGSIFEGFGLSI 408
Query: 2806 IFFM----YAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLA 2973
+FF+ YA AF+ G I V+ V VF +I + + V KAR A
Sbjct: 409 MFFVIYAAYALAFFYGGILVSNGQADSGIVINVFMSILIGSFSMAMLAPELAAVTKARGA 468
Query: 2974 ASLLFYLIEHPTPIDSLSDSGIVKP--ITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAG 3147
A+ LF I+ IDS S+ G KP + G IS NV F+YP+R +L+GFT +AG
Sbjct: 469 AAKLFATIDRVPAIDSASEEGF-KPDGLRGEISFENVKFHYPSRPSIPILKGFTTTFEAG 527
Query: 3148 KTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLF 3327
KT ALVG SG GKST++ L+ERFY+ G++ +DG +IR+LN++ LR+Q+ +VSQEPTLF
Sbjct: 528 KTFALVGASGSGKSTVVSLIERFYDPVSGVVKLDGRDIRSLNLNWLRQQIGLVSQEPTLF 587
Query: 3328 DCTIGENICYG----TNRNVTYQEIVEAAKM----ANIHNFILGLPDGYDTHVGEKGTQL 3483
T+ N+ +G N + +E E K AN HNFI+ LP GYDT VGE+G L
Sbjct: 588 GTTVRGNVEHGLIGSRYENASLEEKFELVKKACVDANAHNFIMKLPQGYDTMVGERGMLL 647
Query: 3484 SGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLST 3663
SGGQKQR+AIARA+V P +LLLDEATSALDT+SE IVQ+ALD A +GRT + IAHRLST
Sbjct: 648 SGGQKQRVAIARAIVSDPRILLLDEATSALDTQSEGIVQDALDKASRGRTTITIAHRLST 707
Query: 3664 IQNSDVIAIVSEGKIVEKGTHDELI-RKSEIYQKFCETQRIVE 3789
I+++D I ++ G+++E+G+H++L+ ++ Y + Q++ +
Sbjct: 708 IRDADRIYVMGGGEVLEQGSHNDLLANENGPYAQLVNNQKLAQ 750
>gi|21464386|gb|AAM51996.1| RE14657p [Drosophila melanogaster]
Length = 1302
Score = 781 bits (2016), Expect = 0.0
Identities = 448/1188 (37%), Positives = 669/1188 (55%), Gaps = 38/1188 (3%)
Frame = +1
Query: 331 VKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNL 510
+ Y I + V+MF + + F A R V ++R +++RQ I W D N
Sbjct: 118 ISYGILLTIASVVMFISGIFSVDVFNMVALRQVTRMRIKLFSSVIRQDIGWHDLASKQNF 177
Query: 511 TARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAK 690
T + DD+E++R+G+ +K V + F+ + F Y W +TL + + PL++L
Sbjct: 178 TQSMVDDVEKIRDGISEKVGHFVYLVVGFIITVAISFSYGWKLTLAVSSYIPLVILLNYY 237
Query: 691 MSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVK 870
++K T EQE+YA AG +AEE SSIRTV S G K E+ R+ N L R+ K
Sbjct: 238 VAKFQGKLTAREQESYAGAGNLAEEILSSIRTVVSFGGEKSEVQRYENFLVPARKASQWK 297
Query: 871 YCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDR-----GLIFTVFFAVLSGSTSL 1035
+ G+ +Y S A AFWYG LII+D + ++ FF ++ G+ ++
Sbjct: 298 GAFSGLSDAVLKSMLYLSCAGAFWYGVNLIIDDRDVENKEYTPAILMIAFFGIIVGADNI 357
Query: 1036 GGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVD-NMKGDISFKDVHFRYPSR 1212
P L SF TARG A+ + +VI+ KIDP S +G L++ ++GD+ F+DV FRYPSR
Sbjct: 358 ARTAPFLESFATARGCATNLFKVIDLTSKIDPLSTDGKLLNYGLRGDVEFQDVFFRYPSR 417
Query: 1213 KDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVH 1392
++ V +G+++ ++AG +ALVGSSGCGKST V LLQRFYDP G VL+D +D+R+ N+
Sbjct: 418 PEVIVHRGLNIRIRAGQTVALVGSSGCGKSTCVQLLQRFYDPVFGSVLLDDLDIRKYNIQ 477
Query: 1393 SLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRV 1572
LR I +V QEPVLF GTI +NI G AT ++ A A A++FI LP+ Y + +
Sbjct: 478 WLRSNIAVVGQEPVLFLGTIAQNISYGKPGATQKEIEAAATQAGAHEFITNLPESYRSMI 537
Query: 1573 GEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTII 1752
GE+G QLSGGQKQRIAIARAL++NPKILLLDEATSALD ++E++VQ ALD A GRTTI+
Sbjct: 538 GERGSQLSGGQKQRIAIARALIQNPKILLLDEATSALDYQSEKQVQQALDLASKGRTTIV 597
Query: 1753 VAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXX-XXXEAGKDIE 1929
V+HRLS IR D+I G ++E GSH++LM+ +G +Y+M E IE
Sbjct: 598 VSHRLSAIRGADKIVFIHDGKVLEEGSHDDLMALEGAYYNMVRAGDINMPDEVEKEDSIE 657
Query: 1930 DTISES-AHSHLXXXXXXXXXXXXXXXIHQLAEEV----------EECKAPP------TS 2058
DT +S A Q E + + +APP +
Sbjct: 658 DTKQKSLALFEKSFETSPLNFEKGQKNSVQFEEPIIKALIKDTNAQSAEAPPEKPNFFRT 717
Query: 2059 MFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSL--PADQMQANVYFWC 2232
+I + + + + P FA+++ E + + P D ++
Sbjct: 718 FSRILQLAKQEWCYLILGTISAVAVGFLYPAFAVIFGEFYAALAEKDPEDALRRTAVL-- 775
Query: 2233 GMFVLMGITFFVGF--FTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKL 2406
+ +G+ F G F G LT ++R F ++ Q++ ++DD + G L
Sbjct: 776 -SWACLGLAFLTGLVCFLQTYLFNYAGIWLTTRMRAMTFNAMVNQEVGWFDDENNSVGAL 834
Query: 2407 CTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYF 2583
R + +A +++ + L ++ ++ ++ + YY W+
Sbjct: 835 SARLSGEAVDIQGAIGYPLSGMIQALSNFISSVSVAMYYNWKLALLCLANCPIIVGSVIL 894
Query: 2584 EMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKH 2763
E +M +R+ Q++EEA ++A++++ +IRTV L R+ Y E ++ +
Sbjct: 895 EAKMMSNAVVREKQVIEEACRIATESITNIRTVAGLRREADVIREYTEEIQRVEVLIRQK 954
Query: 2764 AHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSF 2943
G + + Q+ FF YA A G + V++ + D+ +V + + M+ + +F
Sbjct: 955 LRWRGVLNSTMQASAFFAYAVALCYGGVLVSEGQLPFQDIIKVSETLLYGSMMLAQSLAF 1014
Query: 2944 IPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVK-------PITGNISIRNVFFNYPTRK 3102
P A +A LF +++ I S G +K + + R + F YPTR
Sbjct: 1015 TPAFSAALIAGHRLFQILDRKPKIQ--SPMGTIKNTLAKQLNLFEGVRYRGIQFRYPTRP 1072
Query: 3103 DTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIR-NLNIS 3279
D K+L G L++ G+TVALVGHSGCGKST + LL+R+Y+ D+G I ID D+I+ +L +
Sbjct: 1073 DAKILNGLDLEVLKGQTVALVGHSGCGKSTCVQLLQRYYDPDEGTIHIDHDDIQHDLTLD 1132
Query: 3280 SLREQVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDT 3456
+R ++ IVSQEPTLF+ +I ENI YG N R+V+ EI+ AAK AN H+FI+ LP+GYDT
Sbjct: 1133 GVRTKLGIVSQEPTLFERSIAENIVYGDNRRSVSMVEIIAAAKSANAHSFIISLPNGYDT 1192
Query: 3457 HVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTC 3636
+G +GTQLSGGQKQRIAIARALVR+P +LLLDEATSALD +SE++VQ+ALD A GRTC
Sbjct: 1193 RMGARGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDLQSEQLVQQALDTACSGRTC 1252
Query: 3637 LVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQR 3780
+VIAHRLST+QN+DVI ++ G++VE+G H +LI + IY K +TQ+
Sbjct: 1253 IVIAHRLSTVQNADVICVIQNGQVVEQGNHMQLISQGGIYAKLHKTQK 1300
Score = 322 bits (825), Expect = 4e-86
Identities = 207/585 (35%), Positives = 325/585 (55%), Gaps = 12/585 (2%)
Frame = +1
Query: 148 LITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSE 327
LI GT++AV G +P A++ G +F + +PE + +
Sbjct: 732 LILGTISAVAVGFLYPAFAVIFG------------EFYAALAEKDPEDALR------RTA 773
Query: 328 VVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQT-- 501
V+ + L L L ++Q F L ++R A++ Q++ WFD +
Sbjct: 774 VLSWAC--LGLAFLTGLVCFLQTYLFNYAGIWLTTRMRAMTFNAMVNQEVGWFDDENNSV 831
Query: 502 GNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLS 681
G L+ARL+ + ++ +G + ++Q + F++ V +Y+W + L+ + P+IV S
Sbjct: 832 GALSARLSGEAVDIQGAIGYPLSGMIQALSNFISSVSVAMYYNWKLALLCLANCPIIVGS 891
Query: 682 GAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTG 861
+K M+ E++ A IA E+ ++IRTV L +RE D E ++
Sbjct: 892 VILEAKMMSNAVVREKQVIEEACRIATESITNIRTVAGL---RREADVIREYTEEIQRVE 948
Query: 862 IV---KYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTS 1032
++ K + G+ + +YA+A YG L+ + +I V +L GS
Sbjct: 949 VLIRQKLRWRGVLNSTMQASAFFAYAVALCYGGVLVSEGQLPFQDII-KVSETLLYGSMM 1007
Query: 1033 LGGALPHLASFGTARGAASTVLRVINSHPKIDPY--SLEGILVD--NMKGDISFKDVHFR 1200
L +L +F A A + ++++ PKI +++ L N+ + ++ + FR
Sbjct: 1008 LAQSLAFTPAFSAALIAGHRLFQILDRKPKIQSPMGTIKNTLAKQLNLFEGVRYRGIQFR 1067
Query: 1201 YPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLR- 1377
YP+R D +L G+ LE+ G +ALVG SGCGKST V LLQR+YDP +G + ID D++
Sbjct: 1068 YPTRPDAKILNGLDLEVLKGQTVALVGHSGCGKSTCVQLLQRYYDPDEGTIHIDHDDIQH 1127
Query: 1378 EVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHD--QVVEACKMANANDFIKRLP 1551
++ + +R ++GIVSQEP LF+ +I ENI G+ + +++ A K ANA+ FI LP
Sbjct: 1128 DLTLDGVRTKLGIVSQEPTLFERSIAENIVYGDNRRSVSMVEIIAAAKSANAHSFIISLP 1187
Query: 1552 DGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQ 1731
+GY TR+G +G QLSGGQKQRIAIARALV+NPKILLLDEATSALD ++E+ VQ ALD A
Sbjct: 1188 NGYDTRMGARGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDLQSEQLVQQALDTAC 1247
Query: 1732 AGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIF 1866
+GRT I++AHRLST++N D I V + G +VE G+H +L+S+ GI+
Sbjct: 1248 SGRTCIVIAHRLSTVQNADVICVIQNGQVVEQGNHMQLISQGGIY 1292
Score = 289 bits (740), Expect = 3e-76
Identities = 194/624 (31%), Positives = 314/624 (50%), Gaps = 44/624 (7%)
Frame = +1
Query: 2017 LAEEVEECKAPPTSMFKIFKFNG-DKVGWXXXXXXXXXXXXSVTPVFALVYAEIF----- 2178
+AE +E + P + K+F+F+ ++GW P ++Y+E
Sbjct: 21 MAEGLEPTE--PIAFLKLFRFSTYGEIGWLFFGFIMCCIKALTLPAVVIIYSEFTSMLVD 78
Query: 2179 ---------NVYSLP----------ADQMQANVYFWCG------MFVLMGITFFVGFFTS 2283
NV++LP A + + N + + + + F+ S
Sbjct: 79 RAMQFGTSSNVHALPLFGGGKTLTNASREENNEALYDDSISYGILLTIASVVMFISGIFS 138
Query: 2284 ANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVFTR-- 2457
+ ++R + F +++RQDI ++D D +R +
Sbjct: 139 VDVFNMVALRQVTRMRIKLFSSVIRQDIGWHD--LASKQNFTQSMVDDVEKIRDGISEKV 196
Query: 2458 ---LPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQL 2628
+ +V+ I+T+ I F YGW+ + Y+ + + R+ +
Sbjct: 197 GHFVYLVVGFIITVA----ISFSYGWKLTLAVSSYIPLVILLNYYVAKFQGKLTAREQES 252
Query: 2629 LEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLI 2808
AG +A + + IRTV S ++ Y +L + G A +S++
Sbjct: 253 YAGAGNLAEEILSSIRTVVSFGGEKSEVQRYENFLVPARKASQWKGAFSGLSDAVLKSML 312
Query: 2809 FFMYAAAFYLG-SIFVNQQAMQPIDVYRVFFAISFCGQMIG-----NTTSFIPDVVKARL 2970
+ A AF+ G ++ ++ + ++ + I+F G ++G T F+ AR
Sbjct: 313 YLSCAGAFWYGVNLIIDDRDVENKEYTPAILMIAFFGIIVGADNIARTAPFLESFATARG 372
Query: 2971 AASLLFYLIEHPTPIDSLSDSG--IVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKA 3144
A+ LF +I+ + ID LS G + + G++ ++VFF YP+R + V +G + I+A
Sbjct: 373 CATNLFKVIDLTSKIDPLSTDGKLLNYGLRGDVEFQDVFFRYPSRPEVIVHRGLNIRIRA 432
Query: 3145 GKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTL 3324
G+TVALVG SGCGKST + LL+RFY+ G +++D +IR NI LR + +V QEP L
Sbjct: 433 GQTVALVGSSGCGKSTCVQLLQRFYDPVFGSVLLDDLDIRKYNIQWLRSNIAVVGQEPVL 492
Query: 3325 FDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQR 3504
F TI +NI YG T +EI AA A H FI LP+ Y + +GE+G+QLSGGQKQR
Sbjct: 493 FLGTIAQNISYG-KPGATQKEIEAAATQAGAHEFITNLPESYRSMIGERGSQLSGGQKQR 551
Query: 3505 IAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVI 3684
IAIARAL+++P +LLLDEATSALD +SEK VQ+ALD A +GRT +V++HRLS I+ +D I
Sbjct: 552 IAIARALIQNPKILLLDEATSALDYQSEKQVQQALDLASKGRTTIVVSHRLSAIRGADKI 611
Query: 3685 AIVSEGKIVEKGTHDELIRKSEIY 3756
+ +GK++E+G+HD+L+ Y
Sbjct: 612 VFIHDGKVLEEGSHDDLMALEGAY 635
>gi|103252|pir||B41249 multidrug resistance protein homolog Mdr65 -
fruit fly (Drosophila melanogaster)
gi|157875|gb|AAA28680.1| P-glycoprotein
Length = 1302
Score = 780 bits (2014), Expect = 0.0
Identities = 447/1188 (37%), Positives = 669/1188 (55%), Gaps = 38/1188 (3%)
Frame = +1
Query: 331 VKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNL 510
+ Y I + V+MF + + F A R V ++R +++RQ I W D N
Sbjct: 118 ISYGILLTIASVVMFISGIFSVDVFNMVALRQVTRMRIKLFSSVIRQDIGWHDLASKQNF 177
Query: 511 TARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAK 690
T + DD+E++R+G+ +K V + F+ + F Y W +TL + + PL++L
Sbjct: 178 TQSMVDDVEKIRDGISEKVGHFVYLVVGFIITVAISFSYGWKLTLAVSSYIPLVILLNYY 237
Query: 691 MSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVK 870
++K T EQE+YA AG +AEE SSIRTV S G K E+ R+ N L R+ K
Sbjct: 238 VAKFQGKLTAREQESYAGAGNLAEEILSSIRTVVSFGGEKSEVQRYENFLVPARKASQWK 297
Query: 871 YCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDR-----GLIFTVFFAVLSGSTSL 1035
+ G+ +Y S A AFWYG LII+D + ++ FF ++ G+ ++
Sbjct: 298 GAFSGLSDAVLKSMLYLSCAGAFWYGVNLIIDDRNVENKEYTPAILMIAFFGIIVGADNI 357
Query: 1036 GGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVD-NMKGDISFKDVHFRYPSR 1212
P L SF +ARG A+ + +VI+ KIDP S +G L++ ++GD+ F+DV FRYPSR
Sbjct: 358 ARTAPFLESFASARGCATNLFKVIDLTSKIDPLSTDGKLLNYGLRGDVEFQDVFFRYPSR 417
Query: 1213 KDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVH 1392
++ V +G+++ ++AG +ALVGSSGCGKST V LLQRFYDP G VL+D +D+R+ N+
Sbjct: 418 PEVIVHRGLNIRIRAGQTVALVGSSGCGKSTCVQLLQRFYDPVFGSVLLDDLDIRKYNIQ 477
Query: 1393 SLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRV 1572
LR I +V QEPVLF GTI +NI G AT ++ A A A++FI LP+ Y + +
Sbjct: 478 WLRSNIAVVGQEPVLFLGTIAQNISYGKPGATQKEIEAAATQAGAHEFITNLPESYRSMI 537
Query: 1573 GEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTII 1752
GE+G QLSGGQKQRIAIARAL++NPKILLLDEATSALD ++E++VQ ALD A GRTTI+
Sbjct: 538 GERGSQLSGGQKQRIAIARALIQNPKILLLDEATSALDYQSEKQVQQALDLASKGRTTIV 597
Query: 1753 VAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXX-XXXEAGKDIE 1929
V+HRLS IR D+I G ++E GSH++LM+ +G +Y+M E IE
Sbjct: 598 VSHRLSAIRGADKIVFIHDGKVLEEGSHDDLMALEGAYYNMVRAGDINMPDEVEKEDSIE 657
Query: 1930 DTISES-AHSHLXXXXXXXXXXXXXXXIHQLAEEV----------EECKAPP------TS 2058
DT +S A Q E + + +APP +
Sbjct: 658 DTKQKSLALFEKSFETSPLNLEKGQKNSVQFEEPIIKALIKDTNAQSAEAPPEKPNFFRT 717
Query: 2059 MFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSL--PADQMQANVYFWC 2232
+I + + + + P FA+++ E + + P D ++
Sbjct: 718 FSRILQLAKQEWCYLILGTISAVAVGFLYPAFAVIFGEFYAALAEKDPEDALRRTAVL-- 775
Query: 2233 GMFVLMGITFFVGF--FTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKL 2406
+ +G+ F G F G LT ++R F ++ Q++ ++DD + G L
Sbjct: 776 -SWACLGLAFLTGLVCFLQTYLFNYAGIWLTTRMRAMTFNAMVNQEVGWFDDENNSVGAL 834
Query: 2407 CTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYF 2583
R + +A +++ + L ++ ++ ++ + YY W+
Sbjct: 835 SARLSGEAVDIQGAIGYPLSGMIQALSNFISSVSVAMYYNWKLALLCLANCPIIVGSVIL 894
Query: 2584 EMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKH 2763
E +M +R+ Q++EEA ++A++++ +IRTV L R+ Y E ++ +
Sbjct: 895 EAKMMSNAVVREKQVIEEACRIATESITNIRTVAGLRREADVIREYTEEIQRVEVLIRQK 954
Query: 2764 AHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSF 2943
G + + Q+ FF YA A G + V++ + D+ +V + + M+ + +F
Sbjct: 955 LRWRGVLNSTMQASAFFAYAVALCYGGVLVSEGQLPFQDIIKVSETLLYGSMMLAQSLAF 1014
Query: 2944 IPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVK-------PITGNISIRNVFFNYPTRK 3102
P A +A LF +++ I S G +K + + R + F YPTR
Sbjct: 1015 TPAFSAALIAGHRLFQILDRKPKIQ--SPMGTIKNTLAKQLNLFEGVRYRGIQFRYPTRP 1072
Query: 3103 DTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIR-NLNIS 3279
D K+L G L++ G+TVALVGHSGCGKST + LL+R+Y+ D+G I ID D+I+ +L +
Sbjct: 1073 DAKILNGLDLEVLKGQTVALVGHSGCGKSTCVQLLQRYYDPDEGTIHIDHDDIQHDLTLD 1132
Query: 3280 SLREQVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDT 3456
+R ++ IVSQEPTLF+ +I ENI YG N R+V+ EI+ AAK AN H+FI+ LP+GYDT
Sbjct: 1133 GVRTKLGIVSQEPTLFERSIAENIAYGDNRRSVSMVEIIAAAKSANAHSFIISLPNGYDT 1192
Query: 3457 HVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTC 3636
+G +GTQLSGGQKQRIAIARALVR+P +LLLDEATSALD +SE++VQ+ALD A GRTC
Sbjct: 1193 RMGARGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDLQSEQLVQQALDTACSGRTC 1252
Query: 3637 LVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQR 3780
+VIAHRLST+QN+DVI ++ G++VE+G H +LI + IY K +TQ+
Sbjct: 1253 IVIAHRLSTVQNADVICVIQNGQVVEQGNHMQLISQGGIYAKLHKTQK 1300
Score = 322 bits (826), Expect = 3e-86
Identities = 207/585 (35%), Positives = 325/585 (55%), Gaps = 12/585 (2%)
Frame = +1
Query: 148 LITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSE 327
LI GT++AV G +P A++ G +F + +PE + +
Sbjct: 732 LILGTISAVAVGFLYPAFAVIFG------------EFYAALAEKDPEDALR------RTA 773
Query: 328 VVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQT-- 501
V+ + L L L ++Q F L ++R A++ Q++ WFD +
Sbjct: 774 VLSWAC--LGLAFLTGLVCFLQTYLFNYAGIWLTTRMRAMTFNAMVNQEVGWFDDENNSV 831
Query: 502 GNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLS 681
G L+ARL+ + ++ +G + ++Q + F++ V +Y+W + L+ + P+IV S
Sbjct: 832 GALSARLSGEAVDIQGAIGYPLSGMIQALSNFISSVSVAMYYNWKLALLCLANCPIIVGS 891
Query: 682 GAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTG 861
+K M+ E++ A IA E+ ++IRTV L +RE D E ++
Sbjct: 892 VILEAKMMSNAVVREKQVIEEACRIATESITNIRTVAGL---RREADVIREYTEEIQRVE 948
Query: 862 IV---KYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTS 1032
++ K + G+ + +YA+A YG L+ + +I V +L GS
Sbjct: 949 VLIRQKLRWRGVLNSTMQASAFFAYAVALCYGGVLVSEGQLPFQDII-KVSETLLYGSMM 1007
Query: 1033 LGGALPHLASFGTARGAASTVLRVINSHPKIDPY--SLEGILVD--NMKGDISFKDVHFR 1200
L +L +F A A + ++++ PKI +++ L N+ + ++ + FR
Sbjct: 1008 LAQSLAFTPAFSAALIAGHRLFQILDRKPKIQSPMGTIKNTLAKQLNLFEGVRYRGIQFR 1067
Query: 1201 YPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLR- 1377
YP+R D +L G+ LE+ G +ALVG SGCGKST V LLQR+YDP +G + ID D++
Sbjct: 1068 YPTRPDAKILNGLDLEVLKGQTVALVGHSGCGKSTCVQLLQRYYDPDEGTIHIDHDDIQH 1127
Query: 1378 EVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHD--QVVEACKMANANDFIKRLP 1551
++ + +R ++GIVSQEP LF+ +I ENI G+ + +++ A K ANA+ FI LP
Sbjct: 1128 DLTLDGVRTKLGIVSQEPTLFERSIAENIAYGDNRRSVSMVEIIAAAKSANAHSFIISLP 1187
Query: 1552 DGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQ 1731
+GY TR+G +G QLSGGQKQRIAIARALV+NPKILLLDEATSALD ++E+ VQ ALD A
Sbjct: 1188 NGYDTRMGARGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDLQSEQLVQQALDTAC 1247
Query: 1732 AGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIF 1866
+GRT I++AHRLST++N D I V + G +VE G+H +L+S+ GI+
Sbjct: 1248 SGRTCIVIAHRLSTVQNADVICVIQNGQVVEQGNHMQLISQGGIY 1292
Score = 290 bits (741), Expect = 2e-76
Identities = 194/624 (31%), Positives = 314/624 (50%), Gaps = 44/624 (7%)
Frame = +1
Query: 2017 LAEEVEECKAPPTSMFKIFKFNG-DKVGWXXXXXXXXXXXXSVTPVFALVYAEIF----- 2178
+AE +E + P + K+F+F+ ++GW P ++Y+E
Sbjct: 21 MAEGLEPTE--PIAFLKLFRFSTYGEIGWLFFGFIMCCIKALTLPAVVIIYSEFTSMLVD 78
Query: 2179 ---------NVYSLP----------ADQMQANVYFWCG------MFVLMGITFFVGFFTS 2283
NV++LP A + + N + + + + F+ S
Sbjct: 79 RAMQFGTSSNVHALPLFGGGKTLTNASREENNEALYDDSISYGILLTIASVVMFISGIFS 138
Query: 2284 ANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVFTR-- 2457
+ ++R + F +++RQDI ++D D +R +
Sbjct: 139 VDVFNMVALRQVTRMRIKLFSSVIRQDIGWHD--LASKQNFTQSMVDDVEKIRDGISEKV 196
Query: 2458 ---LPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQL 2628
+ +V+ I+T+ I F YGW+ + Y+ + + R+ +
Sbjct: 197 GHFVYLVVGFIITVA----ISFSYGWKLTLAVSSYIPLVILLNYYVAKFQGKLTAREQES 252
Query: 2629 LEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLI 2808
AG +A + + IRTV S ++ Y +L + G A +S++
Sbjct: 253 YAGAGNLAEEILSSIRTVVSFGGEKSEVQRYENFLVPARKASQWKGAFSGLSDAVLKSML 312
Query: 2809 FFMYAAAFYLG-SIFVNQQAMQPIDVYRVFFAISFCGQMIG-----NTTSFIPDVVKARL 2970
+ A AF+ G ++ ++ + ++ + I+F G ++G T F+ AR
Sbjct: 313 YLSCAGAFWYGVNLIIDDRNVENKEYTPAILMIAFFGIIVGADNIARTAPFLESFASARG 372
Query: 2971 AASLLFYLIEHPTPIDSLSDSG--IVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKA 3144
A+ LF +I+ + ID LS G + + G++ ++VFF YP+R + V +G + I+A
Sbjct: 373 CATNLFKVIDLTSKIDPLSTDGKLLNYGLRGDVEFQDVFFRYPSRPEVIVHRGLNIRIRA 432
Query: 3145 GKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTL 3324
G+TVALVG SGCGKST + LL+RFY+ G +++D +IR NI LR + +V QEP L
Sbjct: 433 GQTVALVGSSGCGKSTCVQLLQRFYDPVFGSVLLDDLDIRKYNIQWLRSNIAVVGQEPVL 492
Query: 3325 FDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQR 3504
F TI +NI YG T +EI AA A H FI LP+ Y + +GE+G+QLSGGQKQR
Sbjct: 493 FLGTIAQNISYG-KPGATQKEIEAAATQAGAHEFITNLPESYRSMIGERGSQLSGGQKQR 551
Query: 3505 IAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVI 3684
IAIARAL+++P +LLLDEATSALD +SEK VQ+ALD A +GRT +V++HRLS I+ +D I
Sbjct: 552 IAIARALIQNPKILLLDEATSALDYQSEKQVQQALDLASKGRTTIVVSHRLSAIRGADKI 611
Query: 3685 AIVSEGKIVEKGTHDELIRKSEIY 3756
+ +GK++E+G+HD+L+ Y
Sbjct: 612 VFIHDGKVLEEGSHDDLMALEGAY 635
>gi|15228506|ref|NP_189528.1| multidrug resistance P-glycoprotein,
putative [Arabidopsis thaliana]
gi|9294227|dbj|BAB02129.1| P-glycoprotein; multi-drug resistance
related; ABC transporter-like protein [Arabidopsis
thaliana]
Length = 1252
Score = 780 bits (2013), Expect = 0.0
Identities = 450/1246 (36%), Positives = 695/1246 (55%), Gaps = 22/1246 (1%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNP 285
+ +F + D LL+ G++ A++HG+ P+ ++ G M VN
Sbjct: 27 FKLFSFADKFDYLLMFVGSLGAIVHGSSMPVFFLLFGQM------------------VNG 68
Query: 286 EGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAIL 465
G + L + EV +Y +Y++ LG+++ F+SY +IAC+ ER V LR+ YL+A+L
Sbjct: 69 FGKNQMDLHQMVHEVSRYSLYFVYLGLVVCFSSYAEIACWMYSGERQVAALRKKYLEAVL 128
Query: 466 RQQIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMT 642
+Q + +FD +TG++ ++ D V++ + +K + + FLAG VGF +W +
Sbjct: 129 KQDVGFFDTDARTGDIVFSVSTDTLLVQDAISEKVGNFIHYLSTFLAGLVVGFVSAWKLA 188
Query: 643 LVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELD 822
L+ + P I +G + ++ T +E+YA AG IAE+ + +RTV+S G + L+
Sbjct: 189 LLSVAVIPGIAFAGGLYAYTLTGITSKSRESYANAGVIAEQAIAQVRTVYSYVGESKALN 248
Query: 823 RFYNA----LEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGL 990
+ +A L++G + G+ K +G+G + CM S+AL FWY I N T D G
Sbjct: 249 AYSDAIQYTLKLGYKAGMAKG--LGLGCTYGIACM--SWALVFWYAGVFIRNGQT-DGGK 303
Query: 991 IFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKG 1170
FT F+ + G SLG + +L +F + A ++ +IN P I L+G +D + G
Sbjct: 304 AFTAIFSAIVGGMSLGQSFSNLGAFSKGKAAGYKLMEIINQRPTIIQDPLDGKCLDQVHG 363
Query: 1171 DISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGR 1350
+I FKDV F YPSR D+ + + ++ +G +A+VG SG GKST+V+L++RFYDP G+
Sbjct: 364 NIEFKDVTFSYPSRPDVMIFRNFNIFFPSGKTVAVVGGSGSGKSTVVSLIERFYDPNSGQ 423
Query: 1351 VLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAN 1530
+L+DGV+++ + + LREQIG+V+QEP LF TI ENI G AT +V A ANA+
Sbjct: 424 ILLDGVEIKTLQLKFLREQIGLVNQEPALFATTILENILYGKPDATMVEVEAAASAANAH 483
Query: 1531 DFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQ 1710
FI LP GY T+VGE+GVQLSGGQKQRIAIARA++K+PKILLLDEATSALD +E VQ
Sbjct: 484 SFITLLPKGYDTQVGERGVQLSGGQKQRIAIARAMLKDPKILLLDEATSALDASSESIVQ 543
Query: 1711 GALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGI------FYD 1872
ALD+ GRTT++VAHRL TIRNVD I V + G +VE+G+HEEL++K G F +
Sbjct: 544 EALDRVMVGRTTVVVAHRLCTIRNVDSIAVIQQGQVVETGTHEELIAKSGAYASLIRFQE 603
Query: 1873 MTXXXXXXXXXXEAGKDIE-----DTISESAHSHLXXXXXXXXXXXXXXXIHQL--AEEV 2031
M + T S S S I + AE
Sbjct: 604 MVGTRDFSNPSTRRTRSTRLSHSLSTKSLSLRSGSLRNLSYSYSTGADGRIEMISNAETD 663
Query: 2032 EECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNV-YSLPADQM 2208
+ +AP +++ K N + + + P FA+V + + V Y D M
Sbjct: 664 RKTRAPENYFYRLLKLNSPEWPYSIMGAVGSILSGFIGPTFAIVMSNMIEVFYYTDYDSM 723
Query: 2209 QANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLR 2388
+ + +++ G+ + GE+LT ++R +LR ++ ++D+
Sbjct: 724 ERKTKEYVFIYIGAGLYAVGAYLIQHYFFSIMGENLTTRVRRMMLSAILRNEVGWFDEDE 783
Query: 2389 HGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXX 2565
H + + R ATDA +V+ + R+ V+L ++ ++ + + F W+
Sbjct: 784 HNSSLIAARLATDAADVKSAIAERISVILQNMTSLLTSFIVAFIVEWRVSLLILGTFPLL 843
Query: 2566 XMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPF 2745
+ + + G + + +A + V +IRTV + N Q + +C LR P
Sbjct: 844 VLANFAQQLSLKGFAGDTAKAHAKTSMIAGEGVSNIRTVAAFNAQSKILSLFCHELRVPQ 903
Query: 2746 NTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMI 2925
+L + T G +F SQ ++ A + G+ V++ V +VF + +
Sbjct: 904 KRSLYRSQTSGFLFGLSQLALYGSEALILWYGAHLVSKGVSTFSKVIKVFVVLVITANSV 963
Query: 2926 GNTTSFIPDVVKARLAASLLFYLIEHPTPID-SLSDSGIVKPITGNISIRNVFFNYPTRK 3102
T S P++++ A +F +++ T ID +D+ V+ I G+I R+V F YP+R
Sbjct: 964 AETVSLAPEIIRGGEAVGSVFSVLDRQTRIDPDDADADPVETIRGDIEFRHVDFAYPSRP 1023
Query: 3103 DTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISS 3282
D V + F L I+AG + ALVG SG GKS+++ ++ERFY+ G +MIDG +IR LN+ S
Sbjct: 1024 DVMVFRDFNLRIRAGHSQALVGASGSGKSSVIAMIERFYDPLAGKVMIDGKDIRRLNLKS 1083
Query: 3283 LREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHV 3462
LR ++ +V QEP LF TI +NI YG + T E+++AA+ AN H FI GLP+GY T V
Sbjct: 1084 LRLKIGLVQQEPALFAATIFDNIAYGKD-GATESEVIDAARAANAHGFISGLPEGYKTPV 1142
Query: 3463 GEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLV 3642
GE+G QLSGGQKQRIAIARA++++P+VLLLDEATSALD ESE ++QEAL+ +GRT +V
Sbjct: 1143 GERGVQLSGGQKQRIAIARAVLKNPTVLLLDEATSALDAESECVLQEALERLMRGRTTVV 1202
Query: 3643 IAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSE-IYQKFCETQ 3777
+AHRLSTI+ D I ++ +G+IVE+G+H EL+ + E Y + + Q
Sbjct: 1203 VAHRLSTIRGVDCIGVIQDGRIVEQGSHSELVSRPEGAYSRLLQLQ 1248
Score = 325 bits (832), Expect = 7e-87
Identities = 206/595 (34%), Positives = 301/595 (49%), Gaps = 8/595 (1%)
Frame = +1
Query: 2026 EVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXX--SVTPVFALVYAEIFNVYS--- 2190
E E+ K FK+F F DK + S PVF L++ ++ N +
Sbjct: 15 EAEKKKEQSLPFFKLFSF-ADKFDYLLMFVGSLGAIVHGSSMPVFFLLFGQMVNGFGKNQ 73
Query: 2191 LPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIA 2370
+ QM V + FV +G+ + C GE LR + + +L+QD+
Sbjct: 74 MDLHQMVHEVSRYSLYFVYLGLVVCFSSYAEIACWMYSGERQVAALRKKYLEAVLKQDVG 133
Query: 2371 FYD-DLRHGTGKLCTRFATDAPNVRYVFT-RLPVVLASIVTICGALGIGFYYGWQXXXXX 2544
F+D D R TG + +TD V+ + ++ + + T L +GF W+
Sbjct: 134 FFDTDAR--TGDIVFSVSTDTLLVQDAISEKVGNFIHYLSTFLAGLVVGFVSAWKLALLS 191
Query: 2545 XXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYC 2724
G G + + AG +A QA+ +RTV+S + + Y
Sbjct: 192 VAVIPGIAFAGGLYAYTLTGITSKSRESYANAGVIAEQAIAQVRTVYSYVGESKALNAYS 251
Query: 2725 EYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAI 2904
+ ++ K G + + +A F+ +F+ + F+
Sbjct: 252 DAIQYTLKLGYKAGMAKGLGLGCTYGIACMSWALVFWYAGVFIRNGQTDGGKAFTAIFSA 311
Query: 2905 SFCGQMIGNTTSFIPDVVKARLAASLLFYLI-EHPTPIDSLSDSGIVKPITGNISIRNVF 3081
G +G + S + K + A L +I + PT I D + + GNI ++V
Sbjct: 312 IVGGMSLGQSFSNLGAFSKGKAAGYKLMEIINQRPTIIQDPLDGKCLDQVHGNIEFKDVT 371
Query: 3082 FNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNI 3261
F+YP+R D + + F + +GKTVA+VG SG GKST++ L+ERFY+ + G I++DG I
Sbjct: 372 FSYPSRPDVMIFRNFNIFFPSGKTVAVVGGSGSGKSTVVSLIERFYDPNSGQILLDGVEI 431
Query: 3262 RNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLP 3441
+ L + LREQ+ +V+QEP LF TI ENI YG + T E+ AA AN H+FI LP
Sbjct: 432 KTLQLKFLREQIGLVNQEPALFATTILENILYG-KPDATMVEVEAAASAANAHSFITLLP 490
Query: 3442 DGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAK 3621
GYDT VGE+G QLSGGQKQRIAIARA+++ P +LLLDEATSALD SE IVQEALD
Sbjct: 491 KGYDTQVGERGVQLSGGQKQRIAIARAMLKDPKILLLDEATSALDASSESIVQEALDRVM 550
Query: 3622 QGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRIV 3786
GRT +V+AHRL TI+N D IA++ +G++VE GTH+ELI KS Y Q +V
Sbjct: 551 VGRTTVVVAHRLCTIRNVDSIAVIQQGQVVETGTHEELIAKSGAYASLIRFQEMV 605
>gi|24324262|gb|AAN28720.2| MDR-like p-glycoprotein [Arabidopsis
thaliana]
Length = 1252
Score = 779 bits (2012), Expect = 0.0
Identities = 450/1246 (36%), Positives = 695/1246 (55%), Gaps = 22/1246 (1%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNP 285
+ +F + D LL+ G++ A++HG+ P+ ++ G M VN
Sbjct: 27 FKLFSFADKFDYLLMFVGSLGAIVHGSSMPVFFLLFGQM------------------VNG 68
Query: 286 EGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAIL 465
G + L + EV +Y +Y++ LG+++ F+SY +IAC+ ER V LR+ YL+A+L
Sbjct: 69 FGKNQMDLHQMVHEVSRYSLYFVYLGLVVCFSSYAEIACWMYSGERQVAALRKKYLEAVL 128
Query: 466 RQQIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMT 642
+Q + +FD +TG++ ++ D V++ + +K + + FLAG VGF +W +
Sbjct: 129 KQDVGFFDTDARTGDIVFSVSTDTLLVQDAISEKVGNFIHYLSTFLAGLVVGFVSAWKLA 188
Query: 643 LVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELD 822
L+ + P I +G + ++ T +E+YA AG IAE+ + +RTV+S G + L+
Sbjct: 189 LLSVAVIPGIAFAGGLYAYTLTGITSKSRESYANAGVIAEQAIAQVRTVYSYVGESKALN 248
Query: 823 RFYNA----LEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGL 990
+ +A L++G + G+ K +G+G + CM S+AL FWY I N T D G
Sbjct: 249 AYSDAIQYTLKLGYKAGMAKG--LGLGCTYGIACM--SWALVFWYAGVFIRNGQT-DGGK 303
Query: 991 IFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKG 1170
FT F+ + G SLG + +L +F + A ++ +IN P I L+G +D + G
Sbjct: 304 AFTAIFSAIVGGMSLGQSFSNLGAFSKGKAAGYKLMEIINQRPTIIQDPLDGKCLDQVHG 363
Query: 1171 DISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGR 1350
+I FKDV F YPSR D+ + + ++ +G +A+VG SG GKST+V+L++RFYDP G+
Sbjct: 364 NIEFKDVTFSYPSRPDVMIFRNFNIFFPSGKTVAVVGGSGSGKSTVVSLIERFYDPNSGQ 423
Query: 1351 VLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAN 1530
+L+DGV+++ + + LREQIG+V+QEP LF TI ENI G AT +V A ANA+
Sbjct: 424 ILLDGVEIKTLQLKFLREQIGLVNQEPALFATTILENILYGKPDATMVEVEAAASAANAH 483
Query: 1531 DFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQ 1710
FI LP GY T+VGE+GVQLSGGQKQRIAIARA++K+PKILLLDEATSALD +E VQ
Sbjct: 484 SFITLLPKGYDTQVGERGVQLSGGQKQRIAIARAMLKDPKILLLDEATSALDASSESIVQ 543
Query: 1711 GALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGI------FYD 1872
ALD+ GRTT++VAHRL TIRNVD I V + G +VE+G+HEEL++K G F +
Sbjct: 544 EALDRVMVGRTTVVVAHRLCTIRNVDSIAVIQQGQVVETGTHEELIAKSGAYASLIRFQE 603
Query: 1873 MTXXXXXXXXXXEAGKDIE-----DTISESAHSHLXXXXXXXXXXXXXXXIHQL--AEEV 2031
M + T S S S I + AE
Sbjct: 604 MVGTRDFSNPSTRRTRSTRLSHSLSTKSLSLRSGSLRNLSYSYSTGADGRIEMISNAETD 663
Query: 2032 EECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNV-YSLPADQM 2208
+ +AP +++ K N + + + P FA+V + + V Y D M
Sbjct: 664 RKTRAPENYFYRLLKLNSPEWPYSIMGAVGSILSGFIGPTFAIVMSNMIEVFYYTDYDSM 723
Query: 2209 QANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLR 2388
+ + +++ G+ + GE+LT ++R +LR ++ ++D+
Sbjct: 724 ERKTKEYVFIYIGAGLYAVGAYLIQHYFFSIMGENLTTRVRRMMLSAILRNEVGWFDEDE 783
Query: 2389 HGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXX 2565
H + + R ATDA +V+ + R+ V+L ++ ++ + + F W+
Sbjct: 784 HNSSLIAARLATDAADVKSAIAERISVILQNMTSLLTSFIVAFIVEWRVSLLILGTFPLL 843
Query: 2566 XMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPF 2745
+ + + G + + +A + V +IRTV + N Q + +C LR P
Sbjct: 844 VLANFAQQLSLKGFAGDTAKAHAKTSMIAGEGVSNIRTVAAFNAQSKILSLFCHELRVPQ 903
Query: 2746 NTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMI 2925
+L + T G +F SQ ++ A + G+ V++ V +VF + +
Sbjct: 904 KRSLYRSQTSGFLFGLSQLALYGSEALILWYGAHLVSKGVSTFSKVIKVFVVLVITANSV 963
Query: 2926 GNTTSFIPDVVKARLAASLLFYLIEHPTPID-SLSDSGIVKPITGNISIRNVFFNYPTRK 3102
T S P++++ A +F +++ T ID +D+ V+ I G+I R+V F YP+R
Sbjct: 964 AETVSLAPEIIRGGEAVGSVFSVLDRQTRIDPDDADADPVETIRGDIEFRHVDFAYPSRP 1023
Query: 3103 DTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISS 3282
D V + F L I+AG + ALVG SG GKS+++ ++ERFY+ G +MIDG +IR LN+ S
Sbjct: 1024 DVMVFRDFNLRIRAGHSQALVGASGSGKSSVIAMIERFYDLLAGKVMIDGKDIRRLNLKS 1083
Query: 3283 LREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHV 3462
LR ++ +V QEP LF TI +NI YG + T E+++AA+ AN H FI GLP+GY T V
Sbjct: 1084 LRLKIGLVQQEPALFAATIFDNIAYGKD-GATESEVIDAARAANAHGFISGLPEGYKTPV 1142
Query: 3463 GEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLV 3642
GE+G QLSGGQKQRIAIARA++++P+VLLLDEATSALD ESE ++QEAL+ +GRT +V
Sbjct: 1143 GERGVQLSGGQKQRIAIARAVLKNPTVLLLDEATSALDAESECVLQEALERLMRGRTTVV 1202
Query: 3643 IAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSE-IYQKFCETQ 3777
+AHRLSTI+ D I ++ +G+IVE+G+H EL+ + E Y + + Q
Sbjct: 1203 VAHRLSTIRGVDCIGVIQDGRIVEQGSHSELVSRPEGAYSRLLQLQ 1248
Score = 325 bits (832), Expect = 7e-87
Identities = 206/595 (34%), Positives = 301/595 (49%), Gaps = 8/595 (1%)
Frame = +1
Query: 2026 EVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXX--SVTPVFALVYAEIFNVYS--- 2190
E E+ K FK+F F DK + S PVF L++ ++ N +
Sbjct: 15 EAEKKKEQSLPFFKLFSF-ADKFDYLLMFVGSLGAIVHGSSMPVFFLLFGQMVNGFGKNQ 73
Query: 2191 LPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIA 2370
+ QM V + FV +G+ + C GE LR + + +L+QD+
Sbjct: 74 MDLHQMVHEVSRYSLYFVYLGLVVCFSSYAEIACWMYSGERQVAALRKKYLEAVLKQDVG 133
Query: 2371 FYD-DLRHGTGKLCTRFATDAPNVRYVFT-RLPVVLASIVTICGALGIGFYYGWQXXXXX 2544
F+D D R TG + +TD V+ + ++ + + T L +GF W+
Sbjct: 134 FFDTDAR--TGDIVFSVSTDTLLVQDAISEKVGNFIHYLSTFLAGLVVGFVSAWKLALLS 191
Query: 2545 XXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYC 2724
G G + + AG +A QA+ +RTV+S + + Y
Sbjct: 192 VAVIPGIAFAGGLYAYTLTGITSKSRESYANAGVIAEQAIAQVRTVYSYVGESKALNAYS 251
Query: 2725 EYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAI 2904
+ ++ K G + + +A F+ +F+ + F+
Sbjct: 252 DAIQYTLKLGYKAGMAKGLGLGCTYGIACMSWALVFWYAGVFIRNGQTDGGKAFTAIFSA 311
Query: 2905 SFCGQMIGNTTSFIPDVVKARLAASLLFYLI-EHPTPIDSLSDSGIVKPITGNISIRNVF 3081
G +G + S + K + A L +I + PT I D + + GNI ++V
Sbjct: 312 IVGGMSLGQSFSNLGAFSKGKAAGYKLMEIINQRPTIIQDPLDGKCLDQVHGNIEFKDVT 371
Query: 3082 FNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNI 3261
F+YP+R D + + F + +GKTVA+VG SG GKST++ L+ERFY+ + G I++DG I
Sbjct: 372 FSYPSRPDVMIFRNFNIFFPSGKTVAVVGGSGSGKSTVVSLIERFYDPNSGQILLDGVEI 431
Query: 3262 RNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLP 3441
+ L + LREQ+ +V+QEP LF TI ENI YG + T E+ AA AN H+FI LP
Sbjct: 432 KTLQLKFLREQIGLVNQEPALFATTILENILYG-KPDATMVEVEAAASAANAHSFITLLP 490
Query: 3442 DGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAK 3621
GYDT VGE+G QLSGGQKQRIAIARA+++ P +LLLDEATSALD SE IVQEALD
Sbjct: 491 KGYDTQVGERGVQLSGGQKQRIAIARAMLKDPKILLLDEATSALDASSESIVQEALDRVM 550
Query: 3622 QGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRIV 3786
GRT +V+AHRL TI+N D IA++ +G++VE GTH+ELI KS Y Q +V
Sbjct: 551 VGRTTVVVAHRLCTIRNVDSIAVIQQGQVVETGTHEELIAKSGAYASLIRFQEMV 605
>gi|49089458|ref|XP_406437.1| hypothetical protein AN2300.2
[Aspergillus nidulans FGSC A4]
gi|40745255|gb|EAA64411.1| hypothetical protein AN2300.2 [Aspergillus
nidulans FGSC A4]
Length = 1343
Score = 778 bits (2009), Expect = 0.0
Identities = 474/1263 (37%), Positives = 680/1263 (53%), Gaps = 32/1263 (2%)
Frame = +1
Query: 91 VKLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGV 270
V ++ +G++ Y +D+L+++ T+ A+ GA PL + F R
Sbjct: 98 VNISFFGLWRYATKMDILIMVISTICAIAAGAALPLFTA-----PSTFQRIM-------- 144
Query: 271 DNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNY 450
L IS DEF E+ K +Y++ LG+ F T YV F E K+R+ Y
Sbjct: 145 -------LYQISYDEFYDELTKNVLYFVYLGIGEFVTVYVSTVGFIYTGEHATQKIREYY 197
Query: 451 LKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYS 630
L++ILRQ I +FDK G +T R+T D +++G+ +K L + A F+ + + +
Sbjct: 198 LESILRQNIGYFDKLGAGEVTTRITADTNLIQDGISEKVGLTLTALATFVTAFIIAYVKY 257
Query: 631 WSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHK 810
W + L+ +VL+ S+ + ++ ++Y G +AEE SSIR +
Sbjct: 258 WKLALICSSTIVALVLTMGGGSQFIIKYSKKSLDSYGAGGTVAEEVISSIRNATAFGTQD 317
Query: 811 RELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGL 990
+ ++ L+ + G MG +G MYS+Y L FW GS ++ D D G
Sbjct: 318 KLAKQYEVHLDEAEKWGTKNQIVMGFMIGAMFGLMYSNYGLGFWMGSRFLV-DGAVDVGD 376
Query: 991 IFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKG 1170
I TV A+L GS SLG P+ +F A AA+ + I+ +DPYS EG +D+ +G
Sbjct: 377 ILTVLMAILIGSFSLGNVSPNAQAFTNAVAAAAKIFGTIDRQSPLDPYSNEGKTLDHFEG 436
Query: 1171 DISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGR 1350
I ++V YPSR ++ V++ +SL + AG ALVG SG GKST+V L++RFY P +G
Sbjct: 437 HIELRNVKHIYPSRPEVTVMEDVSLSMPAGKTTALVGPSGSGKSTVVGLVERFYMPVRGT 496
Query: 1351 VLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMG-----NEHATHDQVVE--- 1506
VL+DG D++++N+ LR+QI +VSQEPVLF TIY+NI+ G E+ + D+V E
Sbjct: 497 VLLDGHDIKDLNLRWLRQQISLVSQEPVLFGTTIYKNIRHGLIGTKYENESEDKVRELIE 556
Query: 1507 -ACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSAL 1683
A KMANA+DFI LP+GY T VG++G LSGGQKQRIAIARA+V +PKILLLDEATSAL
Sbjct: 557 NAAKMANAHDFITALPEGYETNVGQRGFLLSGGQKQRIAIARAVVSDPKILLLDEATSAL 616
Query: 1684 DTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGI 1863
DT++E VQ AL++A GRTTI++AHRLSTI+ I V G I E G+H+EL+ + G
Sbjct: 617 DTKSEGVVQAALERAAEGRTTIVIAHRLSTIKTAHNIVVLVNGKIAEQGTHDELVDRGGA 676
Query: 1864 FYDMT-XXXXXXXXXXEAGKDIE-------DTISESAHSHLXXXXXXXXXXXXXXXIHQL 2019
+ + +A +D + D S H+
Sbjct: 677 YRKLVEAQRINEQKEADALEDADAEDLTNADIAKIKTASSASSDLDGKPTTIDRTGTHKS 736
Query: 2020 AEEVEECKAPPTSMFK---------IFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAE 2172
K PP + K + FN ++ + P A++YA+
Sbjct: 737 VSSAILSKRPPETTPKYSLWTLLKFVASFNRPEIPYMLIGLVFSVLAGGGQPTQAVLYAK 796
Query: 2173 IFNVYSLPADQ---MQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAF 2343
+ SLP Q ++ + FW MF ++GI F+ T+ C E L + R AF
Sbjct: 797 AISTLSLPESQYSKLRHDADFWSLMFFVVGIIQFITQSTNGAAFAVCSERLIRRARSTAF 856
Query: 2344 KNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVF-TRLPVVLASIVTICGALGIGFYY 2520
+ +LRQDIAF+D + TG L + +T+ ++ V L +L + T+ A+ I
Sbjct: 857 RTILRQDIAFFDKEENSTGALTSFLSTETKHLSGVSGVTLGTILMTSTTLGAAIIIALAI 916
Query: 2521 GWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQ 2700
GW+ G++ M Q R E + A +A IRTV SL R+
Sbjct: 917 GWKLALVCISVVPVLLACGFYRFYMLAQFQSRSKLAYEGSANFACEATSSIRTVASLTRE 976
Query: 2701 EQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPID 2880
Y L T+L ++A SQ+L+FF A F+ G +
Sbjct: 977 RDVWEIYHAQLDAQGRTSLISVLRSSLLYASSQALVFFCVALGFWYGGTLLGHHEYDIFR 1036
Query: 2881 VYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITG 3057
+ F I F Q G SF PD+ KA+ AA+ L + ID+ S+ G ++ + G
Sbjct: 1037 FFVCFSEILFGAQSAGTVFSFAPDMGKAKNAAAEFRRLFDRKPQIDNWSEEGEKLETVEG 1096
Query: 3058 NISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGM 3237
I RNV F YPTR + VL+G L +K G+ VALVG SGCGKST + LLERFY+ G
Sbjct: 1097 EIEFRNVHFRYPTRPEQPVLRGLDLTVKPGQYVALVGPSGCGKSTTIALLERFYDAIAGS 1156
Query: 3238 IMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYG-TNRNVTYQEIVEAAKMAN 3414
I++DG +I LNI+S R + +VSQEPTL+ TI ENI G +V + +++A K AN
Sbjct: 1157 ILVDGKDISKLNINSYRSFLSLVSQEPTLYQGTIKENILLGIVEDDVPEEFLIKACKDAN 1216
Query: 3415 IHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKI 3594
I++FI+ LP+G++T VG KG LSGGQKQR+AIARAL+R P +LLLDEATSALD+ESEK+
Sbjct: 1217 IYDFIMSLPEGFNTVVGSKGGMLSGGQKQRVAIARALLRDPKILLLDEATSALDSESEKV 1276
Query: 3595 VQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCET 3774
VQ ALDAA +GRT + +AHRLSTIQ +DVI + +GKIVE GTH EL++K Y +
Sbjct: 1277 VQAALDAAARGRTTIAVAHRLSTIQKADVIYVFDQGKIVESGTHSELVQKKGRYYELVNL 1336
Query: 3775 QRI 3783
Q +
Sbjct: 1337 QSL 1339
Score = 331 bits (849), Expect = 7e-89
Identities = 204/544 (37%), Positives = 307/544 (55%), Gaps = 12/544 (2%)
Frame = +1
Query: 2200 DQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYD 2379
D++ NV + FV +GI FV + S GE T K+R +++LRQ+I ++D
Sbjct: 155 DELTKNVLY----FVYLGIGEFVTVYVSTVGFIYTGEHATQKIREYYLESILRQNIGYFD 210
Query: 2380 DLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIVTICGALGIGFYYGWQXXX--XXXX 2550
L G G++ TR D ++ + ++ + L ++ T A I + W+
Sbjct: 211 KL--GAGEVTTRITADTNLIQDGISEKVGLTLTALATFVTAFIIAYVKYWKLALICSSTI 268
Query: 2551 XXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEY 2730
MGG + +++ K+ D+ G VA + + IR + Q++ Y +
Sbjct: 269 VALVLTMGGGSQFIIKYSKKSLDSY--GAGGTVAEEVISSIRNATAFGTQDKLAKQYEVH 326
Query: 2731 LREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISF 2910
L E K+ G + L++ Y F++GS F+ A+ D+ V AI
Sbjct: 327 LDEAEKWGTKNQIVMGFMIGAMFGLMYSNYGLGFWMGSRFLVDGAVDVGDILTVLMAILI 386
Query: 2911 CGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFN 3087
+GN + A AA+ +F I+ +P+D S+ G + G+I +RNV
Sbjct: 387 GSFSLGNVSPNAQAFTNAVAAAAKIFGTIDRQSPLDPYSNEGKTLDHFEGHIELRNVKHI 446
Query: 3088 YPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRN 3267
YP+R + V++ +L + AGKT ALVG SG GKST++GL+ERFY +G +++DG +I++
Sbjct: 447 YPSRPEVTVMEDVSLSMPAGKTTALVGPSGSGKSTVVGLVERFYMPVRGTVLLDGHDIKD 506
Query: 3268 LNISSLREQVCIVSQEPTLFDCTIGENICYG-------TNRNVTYQEIVE-AAKMANIHN 3423
LN+ LR+Q+ +VSQEP LF TI +NI +G +E++E AAKMAN H+
Sbjct: 507 LNLRWLRQQISLVSQEPVLFGTTIYKNIRHGLIGTKYENESEDKVRELIENAAKMANAHD 566
Query: 3424 FILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQE 3603
FI LP+GY+T+VG++G LSGGQKQRIAIARA+V P +LLLDEATSALDT+SE +VQ
Sbjct: 567 FITALPEGYETNVGQRGFLLSGGQKQRIAIARAVVSDPKILLLDEATSALDTKSEGVVQA 626
Query: 3604 ALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRI 3783
AL+ A +GRT +VIAHRLSTI+ + I ++ GKI E+GTHDEL+ + Y+K E QRI
Sbjct: 627 ALERAAEGRTTIVIAHRLSTIKTAHNIVVLVNGKIAEQGTHDELVDRGGAYRKLVEAQRI 686
Query: 3784 VESQ 3795
E +
Sbjct: 687 NEQK 690
>gi|50260330|gb|EAL22989.1| hypothetical protein CNBA7570
[Cryptococcus neoformans var. neoformans B-3501A]
Length = 1408
Score = 777 bits (2007), Expect = 0.0
Identities = 470/1271 (36%), Positives = 703/1271 (54%), Gaps = 45/1271 (3%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNP 285
+ +F + ++++ ++ G V AV G PL+ ++ G +TT F +++ V V+ ++
Sbjct: 142 FALFRFAAPLEIVAMVLGLVLAVAAGCCQPLMTLIFGRLTTSF-----TNYAVIVNQISQ 196
Query: 286 EGLVP-------ISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQ 444
GL P + D+ ++ +Y + +G+ MF +++ + + E ++R+
Sbjct: 197 VGLTPETSAALQAAKDDLKTQSGHNALYLMAIGIAMFLATWLYMFIWNVTGELNSKRIRE 256
Query: 445 NYLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFF 624
YL A+LRQ+I +FD G + R+ D V+EG +K AL+ Q F+ G+ + F
Sbjct: 257 RYLAAVLRQEIAYFDDLGAGEVATRIQTDCHLVQEGTSEKVALVFQYAGTFVCGFVLAFV 316
Query: 625 YSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNG 804
S + ++ P+I+L G M +MA + A AG++AEE +SIRTV +
Sbjct: 317 RSPRLAGALISILPVIMLCGGIMMTAMAKFGTAALDHIAKAGSLAEEVIASIRTVQAFGK 376
Query: 805 HKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDR 984
K D+F + +E + G + G G+ +Y++YALAF+YG L+ + D
Sbjct: 377 EKILGDKFADHIEQSKIVGRKGSIFEGFGLSIMFFAIYAAYALAFFYGGVLV-SQGRADS 435
Query: 985 GLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNM 1164
G++ VF ++L GS S+ P LA+ ARGAA+ + I+ P ID S EG+ D++
Sbjct: 436 GIVINVFMSILIGSFSMAMLAPELAAVTKARGAAAKLFATIDRVPTIDSASDEGLKPDSL 495
Query: 1165 KGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTK 1344
G+ISF++V F YPSR + +LKG + +AG ALVG+SG GKST+V+L++RFYDP
Sbjct: 496 HGEISFENVKFHYPSRPSVPILKGFTTTFEAGKTFALVGASGSGKSTVVSLIERFYDPIS 555
Query: 1345 GRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMG-----NEHATHDQ---- 1497
G V +DG D+R +N++ LR+QIG+VSQEP LF T+ N++ G E+A+ ++
Sbjct: 556 GVVKLDGKDIRSLNLNWLRQQIGLVSQEPTLFGTTVRGNVEHGLIGSRYENASFEEKFEL 615
Query: 1498 VVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATS 1677
V +AC ANA+DFI +LP GY T VGE+G+ LSGGQKQR+AIARA+V +P+ILLLDEATS
Sbjct: 616 VKKACVDANAHDFIMKLPQGYDTMVGERGMLLSGGQKQRVAIARAIVSDPRILLLDEATS 675
Query: 1678 ALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQ 1857
ALDT++E VQ ALD+A GRTTI +AHRLSTIR+ DRI+V G ++E GSH +L++ +
Sbjct: 676 ALDTQSEGIVQDALDKASRGRTTITIAHRLSTIRDADRIYVMGGGEVLEQGSHNDLLANE 735
Query: 1858 -GIFYDMTXXXXXXXXXXEAGKDIEDTISE----------------SAHSHLXXXXXXXX 1986
G + + ++D I + H
Sbjct: 736 NGPYAQLVNNQKLAQEAAAEALQVDDDIDDPDDVVFGGPSSPMQEKDRQLHRAVTGRSLA 795
Query: 1987 XXXXXXXIHQLAEEVEECKAPPTSM---FKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFA 2157
+ AEEV P+S ++ + N V P A
Sbjct: 796 SIAMDDIQAKRAEEVAGEDKIPSSFGLYARLLRMNSADKFIYIIAFIAAICAGMVYPALA 855
Query: 2158 LVYAEIFNVYSL--PADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLR 2331
+++ + + + + P + A F+ FV FF SA G L LR
Sbjct: 856 ILFGKALSDFEIQDPTELRDALSRRALWYFITALAAGFVIFFQSAG-FSHAGWDLNGVLR 914
Query: 2332 FEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVF-TRLPVVLASIVTICGALGI 2508
+ F + LR DI ++D+ + TG + + A V+ +F L ++ S T+ G I
Sbjct: 915 KKLFTSTLRHDIEWFDEEHNSTGAVTSNLADQPQKVQGLFGPTLGTIIQSCATLLGGCII 974
Query: 2509 GFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHS 2688
G YG GGY +++ K R +L + +AS+A ++TV S
Sbjct: 975 GLCYGPLLALIGIACIPILVSGGYIRLKVVVLKDQRMKKLHAASAHLASEAAGAVKTVAS 1034
Query: 2689 LNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAM 2868
L R++ Y E L+ P N + + +FA SQ L F + A FY+G++++
Sbjct: 1035 LTREKDVREIYSEALKAPMKLNFRTSIKSQCLFAASQGLTFCIIALVFYIGALWIINGKY 1094
Query: 2869 QPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIV-- 3042
Y V +I F GN +F+PD KA +A+ +F I++ I++ S G V
Sbjct: 1095 TTASFYTVLNSIVFASIQAGNVFTFVPDASKANSSAASIFRSIDNEPAINAESSEGKVLD 1154
Query: 3043 -KPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFY 3219
+ + G++ I V F YPTR +VL+ T+D+ AG VALVG SGCGKST + +LERFY
Sbjct: 1155 HEHVVGHVRIEGVHFRYPTRPGVRVLRNLTIDVPAGTYVALVGPSGCGKSTTIQMLERFY 1214
Query: 3220 NQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNR---NVTYQEI 3390
+ G + +DG +I+ LN++S R Q+ +VSQEPTL+ TI NI G N+ VT EI
Sbjct: 1215 DPLAGRVTLDGIDIKELNLASYRSQISLVSQEPTLYAGTIRFNILLGANKPLEEVTQDEI 1274
Query: 3391 VEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSA 3570
A K ANI++FI+ LPDG+DT VG KG+QLSGGQKQRIAIARAL+R+P VLLLDEATSA
Sbjct: 1275 DSACKDANIYDFIVSLPDGFDTEVGGKGSQLSGGQKQRIAIARALIRNPKVLLLDEATSA 1334
Query: 3571 LDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSE 3750
LD++SEK+VQEALD A +GRT + IAHRLS+IQ+SD I SEG++ E+GTH EL+ K
Sbjct: 1335 LDSQSEKVVQEALDKAAKGRTTIAIAHRLSSIQHSDQIYYFSEGRVAEQGTHQELLSKKG 1394
Query: 3751 IYQKFCETQRI 3783
Y + + Q +
Sbjct: 1395 GYYELVQMQNL 1405
Score = 309 bits (791), Expect = 4e-82
Identities = 201/536 (37%), Positives = 301/536 (55%), Gaps = 22/536 (4%)
Frame = +1
Query: 2248 MGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATD 2427
+GI F+ + GE + ++R +LRQ+IA++DDL G G++ TR TD
Sbjct: 228 IGIAMFLATWLYMFIWNVTGELNSKRIRERYLAAVLRQEIAYFDDL--GAGEVATRIQTD 285
Query: 2428 APNVRYVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXX-----MGGYFEMQ 2592
V+ + +A + G GF + GG
Sbjct: 286 CHLVQEGTSEK---VALVFQYAGTFVCGFVLAFVRSPRLAGALISILPVIMLCGGIMMTA 342
Query: 2593 M-RFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAH 2769
M +FG D + +AG +A + + IRTV + +++ + +++ + K
Sbjct: 343 MAKFGTAALDH--IAKAGSLAEEVIASIRTVQAFGKEKILGDKFADHIEQSKIVGRK--- 397
Query: 2770 TYGAVF-AFSQSLIFFM----YAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNT 2934
G++F F S++FF YA AF+ G + V+Q V VF +I +
Sbjct: 398 --GSIFEGFGLSIMFFAIYAAYALAFFYGGVLVSQGRADSGIVINVFMSILIGSFSMAML 455
Query: 2935 TSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKP--ITGNISIRNVFFNYPTRKDT 3108
+ V KAR AA+ LF I+ IDS SD G+ KP + G IS NV F+YP+R
Sbjct: 456 APELAAVTKARGAAAKLFATIDRVPTIDSASDEGL-KPDSLHGEISFENVKFHYPSRPSV 514
Query: 3109 KVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLR 3288
+L+GFT +AGKT ALVG SG GKST++ L+ERFY+ G++ +DG +IR+LN++ LR
Sbjct: 515 PILKGFTTTFEAGKTFALVGASGSGKSTVVSLIERFYDPISGVVKLDGKDIRSLNLNWLR 574
Query: 3289 EQVCIVSQEPTLFDCTIGENICYGT----NRNVTYQEIVEAAKMA----NIHNFILGLPD 3444
+Q+ +VSQEPTLF T+ N+ +G N +++E E K A N H+FI+ LP
Sbjct: 575 QQIGLVSQEPTLFGTTVRGNVEHGLIGSRYENASFEEKFELVKKACVDANAHDFIMKLPQ 634
Query: 3445 GYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQ 3624
GYDT VGE+G LSGGQKQR+AIARA+V P +LLLDEATSALDT+SE IVQ+ALD A +
Sbjct: 635 GYDTMVGERGMLLSGGQKQRVAIARAIVSDPRILLLDEATSALDTQSEGIVQDALDKASR 694
Query: 3625 GRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELI-RKSEIYQKFCETQRIVE 3789
GRT + IAHRLSTI+++D I ++ G+++E+G+H++L+ ++ Y + Q++ +
Sbjct: 695 GRTTITIAHRLSTIRDADRIYVMGGGEVLEQGSHNDLLANENGPYAQLVNNQKLAQ 750
>gi|26449438|dbj|BAC41846.1| putative P-glycoprotein [Arabidopsis
thaliana]
Length = 1252
Score = 776 bits (2005), Expect = 0.0
Identities = 449/1246 (36%), Positives = 694/1246 (55%), Gaps = 22/1246 (1%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNP 285
+ +F + D LL+ G++ A++HG+ P+ ++ G M VN
Sbjct: 27 FKLFSFADKFDYLLMFVGSLGAIVHGSSMPVFFLLFGQM------------------VNG 68
Query: 286 EGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAIL 465
G + L + EV +Y +Y++ LG+++ F+SY +IAC+ ER V LR+ YL+A+L
Sbjct: 69 FGKNQMDLHQMVHEVSRYSLYFVYLGLVVCFSSYAEIACWMYSGERQVAALRKKYLEAVL 128
Query: 466 RQQIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMT 642
+Q + +FD +TG++ ++ D V++ + +K + + FLAG VGF +W +
Sbjct: 129 KQDVGFFDTDARTGDIVFSVSTDTLLVQDAISEKVGNFIHYLSTFLAGLVVGFVSAWKLA 188
Query: 643 LVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELD 822
L+ + P I +G + ++ T +E+YA AG IAE+ + +RTV+S G + L+
Sbjct: 189 LLSVAVIPGIAFAGGLYAYTLTGITSKSRESYANAGVIAEQAIAQVRTVYSYVGESKALN 248
Query: 823 RFYNA----LEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGL 990
+ +A L++G + G+ K +G+G + CM S+AL FWY I N T D G
Sbjct: 249 AYSDAIQYTLKLGYKAGMAKG--LGLGCTYGIACM--SWALVFWYAGVFIRNGQT-DGGK 303
Query: 991 IFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKG 1170
FT F+ + G SLG + +L +F + A ++ +IN P I L+G +D + G
Sbjct: 304 AFTAIFSAIVGGMSLGQSFSNLGAFSKGKAAGYKLMEIINQRPTIIQDPLDGKCLDQVHG 363
Query: 1171 DISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGR 1350
+I FKDV F YPSR D+ + + ++ +G +A+VG SG GKST+V+L++RFYDP G+
Sbjct: 364 NIEFKDVTFSYPSRPDVMIFRNFNIFFPSGKTVAVVGGSGSGKSTVVSLIERFYDPNSGQ 423
Query: 1351 VLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAN 1530
+L+DGV+++ + + LREQIG+V+QEP LF TI ENI G AT +V A ANA+
Sbjct: 424 ILLDGVEIKTLQLKFLREQIGLVNQEPALFATTILENILYGKPDATMVEVEAAASAANAH 483
Query: 1531 DFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQ 1710
FI LP GY T+VGE+GVQLSGGQKQRIAIARA++K+PKILLLDEATSALD +E VQ
Sbjct: 484 SFITLLPKGYDTQVGERGVQLSGGQKQRIAIARAMLKDPKILLLDEATSALDASSESIVQ 543
Query: 1711 GALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGI------FYD 1872
ALD+ GRTT++VAHRL TIRNVD I V + G +VE+G+HEEL++K G F +
Sbjct: 544 EALDRVMVGRTTVVVAHRLCTIRNVDSIAVIQQGQVVETGTHEELIAKSGAYASLIRFQE 603
Query: 1873 MTXXXXXXXXXXEAGKDIE-----DTISESAHSHLXXXXXXXXXXXXXXXIHQL--AEEV 2031
M + T S S S I + AE
Sbjct: 604 MVGTRDFSNPSTRRTRSTRLSHSLSTKSLSLRSGSLRNLSYSYSTGADGRIEMISNAETD 663
Query: 2032 EECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNV-YSLPADQM 2208
+ +AP +++ K N + + + P FA+V + + V Y D M
Sbjct: 664 RKTRAPENYFYRLLKLNSPEWPYSIMGAVGSILSGFIGPTFAIVMSNMIEVFYYTDYDSM 723
Query: 2209 QANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLR 2388
+ + +++ G+ + GE+LT ++R +LR ++ ++D+
Sbjct: 724 ERKTKEYVFIYIGAGLYAVGAYLIQHYFFSIMGENLTTRVRRMMLSAILRNEVGWFDEDE 783
Query: 2389 HGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXX 2565
H + + R ATDA +V+ + R+ V+L ++ ++ + + F W+
Sbjct: 784 HNSSLIAARLATDAADVKSAIAERISVILQNMTSLLTSFIVAFIVEWRVSLLILGTFPLL 843
Query: 2566 XMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPF 2745
+ + + G + + +A + V +IRTV + N Q + +C LR P
Sbjct: 844 VLANFAQQLSLKGFAGDTAKAHAKTSMIAGEGVSNIRTVAAFNAQSKILSLFCHELRVPQ 903
Query: 2746 NTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMI 2925
+L + T G +F SQ ++ A + G+ V++ V +VF + +
Sbjct: 904 KRSLYRSQTSGFLFGLSQLALYGSEALILWYGAHLVSKGVSTFSKVIKVFVVLVITANSV 963
Query: 2926 GNTTSFIPDVVKARLAASLLFYLIEHPTPID-SLSDSGIVKPITGNISIRNVFFNYPTRK 3102
T S P++++ A +F +++ T ID +D+ V+ I G+I R+V F YP+R
Sbjct: 964 AETVSLAPEIIRGGEAVGSVFSVLDRQTRIDPDDADADPVETIRGDIEFRHVDFAYPSRP 1023
Query: 3103 DTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISS 3282
D V + F L I+AG + ALVG SG GKS+++ ++ERFY+ G +MIDG +IR LN+ S
Sbjct: 1024 DVMVFRDFNLRIRAGHSQALVGASGSGKSSVIAMIERFYDPLAGKVMIDGKDIRRLNLKS 1083
Query: 3283 LREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHV 3462
LR ++ +V QEP LF TI +NI YG + T E+++AA+ AN H FI GLP+GY T V
Sbjct: 1084 LRLKIGLVQQEPALFAATIFDNIAYGKD-GATESEVIDAARAANAHGFISGLPEGYKTPV 1142
Query: 3463 GEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLV 3642
GE+G QLSGGQKQRIAIARA++++P+VLLLDEATSALD ESE ++QEAL+ +GRT +V
Sbjct: 1143 GERGVQLSGGQKQRIAIARAVLKNPTVLLLDEATSALDAESECVLQEALERLMRGRTTVV 1202
Query: 3643 IAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSE-IYQKFCETQ 3777
+AHRLSTI+ D I ++ + +IVE+G+H EL+ + E Y + + Q
Sbjct: 1203 VAHRLSTIRGVDCIGVIQDERIVEQGSHSELVSRPEGAYSRLLQLQ 1248
Score = 325 bits (832), Expect = 7e-87
Identities = 206/595 (34%), Positives = 301/595 (49%), Gaps = 8/595 (1%)
Frame = +1
Query: 2026 EVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXX--SVTPVFALVYAEIFNVYS--- 2190
E E+ K FK+F F DK + S PVF L++ ++ N +
Sbjct: 15 EAEKKKEQSLPFFKLFSF-ADKFDYLLMFVGSLGAIVHGSSMPVFFLLFGQMVNGFGKNQ 73
Query: 2191 LPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIA 2370
+ QM V + FV +G+ + C GE LR + + +L+QD+
Sbjct: 74 MDLHQMVHEVSRYSLYFVYLGLVVCFSSYAEIACWMYSGERQVAALRKKYLEAVLKQDVG 133
Query: 2371 FYD-DLRHGTGKLCTRFATDAPNVRYVFT-RLPVVLASIVTICGALGIGFYYGWQXXXXX 2544
F+D D R TG + +TD V+ + ++ + + T L +GF W+
Sbjct: 134 FFDTDAR--TGDIVFSVSTDTLLVQDAISEKVGNFIHYLSTFLAGLVVGFVSAWKLALLS 191
Query: 2545 XXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYC 2724
G G + + AG +A QA+ +RTV+S + + Y
Sbjct: 192 VAVIPGIAFAGGLYAYTLTGITSKSRESYANAGVIAEQAIAQVRTVYSYVGESKALNAYS 251
Query: 2725 EYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAI 2904
+ ++ K G + + +A F+ +F+ + F+
Sbjct: 252 DAIQYTLKLGYKAGMAKGLGLGCTYGIACMSWALVFWYAGVFIRNGQTDGGKAFTAIFSA 311
Query: 2905 SFCGQMIGNTTSFIPDVVKARLAASLLFYLI-EHPTPIDSLSDSGIVKPITGNISIRNVF 3081
G +G + S + K + A L +I + PT I D + + GNI ++V
Sbjct: 312 IVGGMSLGQSFSNLGAFSKGKAAGYKLMEIINQRPTIIQDPLDGKCLDQVHGNIEFKDVT 371
Query: 3082 FNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNI 3261
F+YP+R D + + F + +GKTVA+VG SG GKST++ L+ERFY+ + G I++DG I
Sbjct: 372 FSYPSRPDVMIFRNFNIFFPSGKTVAVVGGSGSGKSTVVSLIERFYDPNSGQILLDGVEI 431
Query: 3262 RNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLP 3441
+ L + LREQ+ +V+QEP LF TI ENI YG + T E+ AA AN H+FI LP
Sbjct: 432 KTLQLKFLREQIGLVNQEPALFATTILENILYG-KPDATMVEVEAAASAANAHSFITLLP 490
Query: 3442 DGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAK 3621
GYDT VGE+G QLSGGQKQRIAIARA+++ P +LLLDEATSALD SE IVQEALD
Sbjct: 491 KGYDTQVGERGVQLSGGQKQRIAIARAMLKDPKILLLDEATSALDASSESIVQEALDRVM 550
Query: 3622 QGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRIV 3786
GRT +V+AHRL TI+N D IA++ +G++VE GTH+ELI KS Y Q +V
Sbjct: 551 VGRTTVVVAHRLCTIRNVDSIAVIQQGQVVETGTHEELIAKSGAYASLIRFQEMV 605
>gi|22328760|ref|NP_193539.2| ABC transporter family protein
[Arabidopsis thaliana]
Length = 1281
Score = 776 bits (2005), Expect = 0.0
Identities = 452/1238 (36%), Positives = 684/1238 (54%), Gaps = 24/1238 (1%)
Frame = +1
Query: 94 KLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVD 273
K++ + +F + D++L+ GT+AA +G P + ++ G + F
Sbjct: 15 KVSFFKLFSFADKTDVVLMTVGTIAAAGNGLTQPFMTLIFGQLINAF------------G 62
Query: 274 NVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYL 453
+P+ +V EV K + ++ L V +++Q++C+ ER +R YL
Sbjct: 63 TTDPDHMV--------REVWKVAVKFIYLAVYSCVVAFLQVSCWMVTGERQSATIRGLYL 114
Query: 454 KAILRQQIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYS 630
K ILRQ I +FD + TG + R++ D +++ +G+K Q+ FL G+ + F+
Sbjct: 115 KTILRQDIGYFDTETNTGEVIGRMSGDTILIQDAMGEKVGKFTQLLCTFLGGFAIAFYKG 174
Query: 631 WSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHK 810
+ V+ PLIV++GA MS M+ Q YA AG + E+T +IRTV + G K
Sbjct: 175 PLLAGVLCSCIPLIVIAGAAMSLIMSKMAGRGQVAYAEAGNVVEQTVGAIRTVVAFTGEK 234
Query: 811 RELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGL 990
+ +++ + LE+ +T + + G G+G ++ SY LA WYG+ LI+ + ++ G
Sbjct: 235 QATEKYESKLEIAYKTVVQQGLISGFGLGTMLAVIFCSYGLAVWYGAKLIM-EKGYNGGQ 293
Query: 991 IFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKG 1170
+ V FAVL+G SLG P L +F R AA + I PKID Y + G ++++++G
Sbjct: 294 VINVIFAVLTGGMSLGQTSPSLNAFAAGRAAAFKMFETIKRSPKIDAYDMSGSVLEDIRG 353
Query: 1171 DISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGR 1350
DI KDV+FRYP+R D+ + G SL + G +ALVG SG GKST+++L++RFYDP G+
Sbjct: 354 DIELKDVYFRYPARPDVQIFAGFSLFVPNGKTVALVGQSGSGKSTVISLIERFYDPESGQ 413
Query: 1351 VLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAN 1530
VLID +DL+++ + +R +IG+VSQEPVLF TI ENI G E AT ++ A ++ANA
Sbjct: 414 VLIDNIDLKKLQLKWIRSKIGLVSQEPVLFATTIKENIAYGKEDATDQEIRTAIELANAA 473
Query: 1531 DFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQ 1710
FI +LP G T VGE G Q+SGGQKQR+AIARA++KNPKILLLDEATSALD E+ER VQ
Sbjct: 474 KFIDKLPQGLDTMVGEHGTQMSGGQKQRLAIARAILKNPKILLLDEATSALDAESERIVQ 533
Query: 1711 GALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELM-SKQGIFYDM---- 1875
AL + RTT++VAHRL+TIR D I V G IVE G+H+E++ +G + +
Sbjct: 534 DALVNLMSNRTTVVVAHRLTTIRTADVIAVVHQGKIVEKGTHDEMIQDPEGAYSQLVRLQ 593
Query: 1876 --TXXXXXXXXXXEAGKDIE------------DTISESAHSHLXXXXXXXXXXXXXXXIH 2013
+ E D+E ++S ++ S ++
Sbjct: 594 EGSKEEATESERPETSLDVERSGSLRLSSAMRRSVSRNSSSSRHSFSLASNMFFPGVNVN 653
Query: 2014 Q---LAEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNV 2184
Q + +E + S+ ++ N ++ +V P+F L+ + N+
Sbjct: 654 QTDEMEDEENNVRHKKVSLKRLAHLNKPEIPVLVLGSIAAMVHGTVFPIFGLLLSSSINM 713
Query: 2185 YSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQD 2364
+ PA ++ + +FW +++ +G+T FV G G L ++R F ++ Q+
Sbjct: 714 FYEPAKILKKDSHFWALIYIALGLTNFVMIPVPNYFFGIAGGKLIKRIRSMCFDKVVHQE 773
Query: 2365 IAFYDDLRHGTGKLCTRFATDAPNVRYVFTRLPVVLASIVTICGALGIGFYYGWQXXXXX 2544
I+++DD A + V L +++ +I T+ L I F W
Sbjct: 774 ISWFDD--------------TANSRSLVGDALALIVQNIATVTTGLIIAFTANWILALIV 819
Query: 2545 XXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYC 2724
+ GY + + G + EEA +VA+ AV IRTV S +E+ Y
Sbjct: 820 LALSPFIVIQGYAQTKFLTGFSADAKAMYEEASQVANDAVSSIRTVASFCAEEKVMDLYQ 879
Query: 2725 EYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAI 2904
+ P ++ GA F FS ++ + F G+ + +V++VFFA+
Sbjct: 880 QKCDGPKKNGVRLGLLSGAGFGFSFFFLYCINCVCFVSGAGLIQIGKATFGEVFKVFFAL 939
Query: 2905 SFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVF 3081
+ + T++ PD KA+ +A+ +F +++ IDS SD G ++ + G+I R+V
Sbjct: 940 TIMAIGVSQTSAMAPDSNKAKDSAASIFDILDSTPKIDSSSDEGTTLQNVNGDIEFRHVS 999
Query: 3082 FNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNI 3261
F YP R D ++ + L I +GKTVALVG SG GKST++ ++ERFYN D G I+ID I
Sbjct: 1000 FRYPMRPDVQIFRDLCLTIPSGKTVALVGESGSGKSTVISMIERFYNPDSGKILIDQVEI 1059
Query: 3262 RNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLP 3441
+ +S LR+Q+ +VSQEP LF+ TI NI YG T +EI+ AAK AN HNFI LP
Sbjct: 1060 QTFKLSWLRQQMGLVSQEPILFNETIRSNIAYGKTGGATEEEIIAAAKAANAHNFISSLP 1119
Query: 3442 DGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAK 3621
GYDT VGE+G QLSGGQKQRIAIARA+++ P +LLLDEATSALD ESE++VQ+ALD
Sbjct: 1120 QGYDTSVGERGVQLSGGQKQRIAIARAILKDPKILLLDEATSALDAESERVVQDALDRVM 1179
Query: 3622 QGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDEL 3735
RT +V+AHRL+TI+N+DVIA+V G I EKG H+ L
Sbjct: 1180 VNRTTVVVAHRLTTIKNADVIAVVKNGVIAEKGRHETL 1217
Score = 321 bits (823), Expect = 7e-86
Identities = 204/570 (35%), Positives = 300/570 (51%), Gaps = 5/570 (0%)
Frame = +1
Query: 2056 SMFKIFKFNGDKVGWXXXXXXXXXXXXS--VTPVFALVYAEIFNVY-SLPADQMQANVYF 2226
S FK+F F DK + P L++ ++ N + + D M V+
Sbjct: 17 SFFKLFSF-ADKTDVVLMTVGTIAAAGNGLTQPFMTLIFGQLINAFGTTDPDHMVREVWK 75
Query: 2227 WCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKL 2406
F+ + + V F +C GE + +R K +LRQDI ++D TG++
Sbjct: 76 VAVKFIYLAVYSCVVAFLQVSCWMVTGERQSATIRGLYLKTILRQDIGYFDT-ETNTGEV 134
Query: 2407 CTRFATDAPNVRYVF-TRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYF 2583
R + D ++ ++ + T G I FY G + G
Sbjct: 135 IGRMSGDTILIQDAMGEKVGKFTQLLCTFLGGFAIAFYKGPLLAGVLCSCIPLIVIAGAA 194
Query: 2584 EMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKH 2763
+ R EAG V Q V IRTV + ++Q Y L + T ++
Sbjct: 195 MSLIMSKMAGRGQVAYAEAGNVVEQTVGAIRTVVAFTGEKQATEKYESKLEIAYKTVVQQ 254
Query: 2764 AHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSF 2943
G ++IF Y A + G+ + ++ V V FA+ G +G T+
Sbjct: 255 GLISGFGLGTMLAVIFCSYGLAVWYGAKLIMEKGYNGGQVINVIFAVLTGGMSLGQTSPS 314
Query: 2944 IPDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTKVLQ 3120
+ R AA +F I+ ID+ SG +++ I G+I +++V+F YP R D ++
Sbjct: 315 LNAFAAGRAAAFKMFETIKRSPKIDAYDMSGSVLEDIRGDIELKDVYFRYPARPDVQIFA 374
Query: 3121 GFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVC 3300
GF+L + GKTVALVG SG GKST++ L+ERFY+ + G ++ID +++ L + +R ++
Sbjct: 375 GFSLFVPNGKTVALVGQSGSGKSTVISLIERFYDPESGQVLIDNIDLKKLQLKWIRSKIG 434
Query: 3301 IVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQ 3480
+VSQEP LF TI ENI YG + T QEI A ++AN FI LP G DT VGE GTQ
Sbjct: 435 LVSQEPVLFATTIKENIAYG-KEDATDQEIRTAIELANAAKFIDKLPQGLDTMVGEHGTQ 493
Query: 3481 LSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLS 3660
+SGGQKQR+AIARA++++P +LLLDEATSALD ESE+IVQ+AL RT +V+AHRL+
Sbjct: 494 MSGGQKQRLAIARAILKNPKILLLDEATSALDAESERIVQDALVNLMSNRTTVVVAHRLT 553
Query: 3661 TIQNSDVIAIVSEGKIVEKGTHDELIRKSE 3750
TI+ +DVIA+V +GKIVEKGTHDE+I+ E
Sbjct: 554 TIRTADVIAVVHQGKIVEKGTHDEMIQDPE 583
>gi|46390486|dbj|BAD15946.1| putative MDR-like ABC transporter [Oryza
sativa (japonica cultivar-group)]
gi|50252693|dbj|BAD28861.1| putative MDR-like ABC transporter [Oryza
sativa (japonica cultivar-group)]
Length = 1285
Score = 775 bits (2001), Expect = 0.0
Identities = 447/1257 (35%), Positives = 692/1257 (54%), Gaps = 47/1257 (3%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F + +D L+ G VAAV +G P LA ++G + F A + V V ++
Sbjct: 33 LFTFADRLDAALMAVGGVAAVANGVAMPFLAFLIGELVDAFGAADRAHVVHVVSKIS--- 89
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
+ + + + ++Q++C+ ER ++R YL+AILRQ
Sbjct: 90 -----------------LRFTYVAIGSGIAGFLQVSCWMVTGERQAARIRGLYLEAILRQ 132
Query: 472 QIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLV 648
I +FD + TG +T R++ D +++ +G+K +Q+ + FL G+ + F W ++LV
Sbjct: 133 DITFFDLETSTGEVTERMSSDTVLIQDAIGEKVGKFLQLLSTFLGGFIIAFARGWLLSLV 192
Query: 649 MMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRF 828
M+ P + L+ A MS +++ Q YA AG + E+T SIRTV S G +R D++
Sbjct: 193 MLSSIPPVALAAAAMSIAISKLANRSQLAYAEAGKLVEQTIGSIRTVVSFTGERRATDKY 252
Query: 829 YNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFF 1008
L++ ++ + + MG+G+G ++ SY LA WYG+ LII + + G I V
Sbjct: 253 NEFLKISYRSAVHQGAAMGLGIGSVMFIVFCSYGLAVWYGAKLII-EKGYTGGYIINVLM 311
Query: 1009 AVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKD 1188
A++SG+ +LG + P L +F + + AA + IN P+ID G++++N GD+ FKD
Sbjct: 312 AIMSGAMALGQSSPCLNAFASGQIAAYKMFATINREPEIDASDRSGLVLENFVGDVEFKD 371
Query: 1189 VHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGV 1368
VHF YP+R + + G S+ + +G +ALVG SG GKST+++L++RFYDP G VL+DGV
Sbjct: 372 VHFSYPARPEQLIFTGFSISIPSGMTMALVGESGSGKSTVISLVERFYDPQSGEVLLDGV 431
Query: 1369 DLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRL 1548
+++ +N+ +R++IG+VSQEP+LF TI ENI+ G + A+ +++ A +ANA FI +L
Sbjct: 432 NMKLLNLSRIRQKIGLVSQEPILFTTTIRENIEYGKKDASEEEIRRAIVLANAAKFIDKL 491
Query: 1549 PDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQA 1728
P+G T VGE G QLSGGQKQRIAIARA++K+P+ILLLDEATSALD E+E VQ AL+
Sbjct: 492 PNGLDTMVGEHGTQLSGGQKQRIAIARAILKDPRILLLDEATSALDAESEHVVQDALNNI 551
Query: 1729 QAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMS-KQGIFYDMTXXXXXXXXX 1905
RTTIIVAHRLST+RN D I V G +VE G H EL+ G +Y +
Sbjct: 552 MVNRTTIIVAHRLSTVRNADTISVLHRGQLVEQGPHAELIKYSNGAYYQLLQLQEVNARR 611
Query: 1906 XEAGK-------DIEDTISESAH--SHLXXXXXXXXXXXXXXXIHQLA------------ 2022
+ D+ + +S+ A+ S I +L+
Sbjct: 612 NGTYELDPNRLSDVANRLSDVANRLSDAANRLSDAGNFVSRHSIRKLSFERSMSRHSSLG 671
Query: 2023 -------------EEVEEC---KAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVF 2154
+E+E C K+ + ++ + + ++ PVF
Sbjct: 672 GSRRNSQTYALTEDEIEGCDDTKSGKNVLRRLLHLHKPETAILLLGCIAASANGAILPVF 731
Query: 2155 ALVYAEIFNVYSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRF 2334
L+ + N + P +++ + FW ++V++G+ G L ++R
Sbjct: 732 GLLLSSAINAFYEPPHKLRKDSVFWAEIYVILGVVSIFIIPVQHTLFNMAGGKLIERIRA 791
Query: 2335 EAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVF-TRLPVVLASIVTICGALGIG 2511
+F ++ QDI ++DD + +G + R + DA +V+ + L +++ SI T + I
Sbjct: 792 LSFSRVVYQDIGWFDDPLNSSGAIGARLSADAASVKSIAGDVLSLIVQSISTALVGIVIA 851
Query: 2512 FYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSL 2691
W+ Y + ++ G ++ E+A +AS A+ +IRTV S
Sbjct: 852 MIANWKLAFIVLCFVPCVFAQSYAQSRLMRGFGADAKEMYEQASTIASDAISNIRTVTSF 911
Query: 2692 NRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQ 2871
E+ +Y + P ++ G + FS +L+F YA +FY+G+ FV+
Sbjct: 912 CVGEKIIESYRNKCKGPVKKGVRQGAISGVGYGFSFALLFCFYAVSFYVGARFVHNGTAD 971
Query: 2872 PIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIV-KP 3048
+V++VFFA++ + ++S D K + AA+ +F +I+ + ID+ SD G+ +
Sbjct: 972 VGEVFKVFFALTMMAVGVSQSSSLARDFSKVQDAAASIFKIIDRKSKIDASSDDGMAPEK 1031
Query: 3049 ITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGK------TVALVGHSGCGKSTIMGLLE 3210
I GNI ++V F YP R D ++ L I +GK TVALVG SG GKST++ LLE
Sbjct: 1032 IEGNIEFQHVSFKYPARTDVQIFTNLCLRIPSGKVHVVLMTVALVGESGSGKSTVVALLE 1091
Query: 3211 RFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEI 3390
RFY+ D G I +DG +++ L ++ LR+Q+ +V QEP LF+ TI NI YG V+ +EI
Sbjct: 1092 RFYDPDSGAIFLDGMDLKTLKLTWLRQQIGLVGQEPVLFNGTIRANIAYGKQDQVSEEEI 1151
Query: 3391 VEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSA 3570
V A+ AN H FI LP GYDT VGE+G QLSGGQKQRIAIARA+++ P VLLLDEATSA
Sbjct: 1152 VAVAEAANAHRFISSLPHGYDTSVGERGVQLSGGQKQRIAIARAILKDPKVLLLDEATSA 1211
Query: 3571 LDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIR 3741
LD+ESE+IVQEALD GRT +++AHRLSTI +D IA++ G + E+G H L+R
Sbjct: 1212 LDSESERIVQEALDRVMVGRTTVIVAHRLSTITGADKIAVIKNGVVAEEGRHGRLLR 1268
Score = 369 bits (946), Expect = e-100
Identities = 212/584 (36%), Positives = 324/584 (55%), Gaps = 9/584 (1%)
Frame = +1
Query: 145 LLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNS 324
+L+ G +AA +GA P+ ++L F + +
Sbjct: 713 ILLLGCIAASANGAILPVFGLLLSSAINAFYEPPH---------------------KLRK 751
Query: 325 EVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDK--QQ 498
+ V + Y++LGV+ F VQ F +L+ ++R ++ Q I WFD
Sbjct: 752 DSVFWAEIYVILGVVSIFIIPVQHTLFNMAGGKLIERIRALSFSRVVYQDIGWFDDPLNS 811
Query: 499 TGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVL 678
+G + ARL+ D V+ GD +L+VQ + L G + +W + +++ F P +
Sbjct: 812 SGAIGARLSADAASVKSIAGDVLSLIVQSISTALVGIVIAMIANWKLAFIVLCFVPCVFA 871
Query: 679 SGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQT 858
S+ M +E Y A IA + S+IRTV S ++ ++ + N + +
Sbjct: 872 QSYAQSRLMRGFGADAKEMYEQASTIASDAISNIRTVTSFCVGEKIIESYRNKCKGPVKK 931
Query: 859 GIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLG 1038
G+ + G+G GFS ++ YA++F+ G+ + N T D G +F VFFA+ + +
Sbjct: 932 GVRQGAISGVGYGFSFALLFCFYAVSFYVGARFVHNG-TADVGEVFKVFFALTMMAVGVS 990
Query: 1039 GALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKD 1218
+ F + AA+++ ++I+ KID S +G+ + ++G+I F+ V F+YP+R D
Sbjct: 991 QSSSLARDFSKVQDAAASIFKIIDRKSKIDASSDDGMAPEKIEGNIEFQHVSFKYPARTD 1050
Query: 1219 IHVLKGISLELKAGD------KIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLRE 1380
+ + + L + +G +ALVG SG GKST+V LL+RFYDP G + +DG+DL+
Sbjct: 1051 VQIFTNLCLRIPSGKVHVVLMTVALVGESGSGKSTVVALLERFYDPDSGAIFLDGMDLKT 1110
Query: 1381 VNVHSLREQIGIVSQEPVLFDGTIYENIKMGNE-HATHDQVVEACKMANANDFIKRLPDG 1557
+ + LR+QIG+V QEPVLF+GTI NI G + + +++V + ANA+ FI LP G
Sbjct: 1111 LKLTWLRQQIGLVGQEPVLFNGTIRANIAYGKQDQVSEEEIVAVAEAANAHRFISSLPHG 1170
Query: 1558 YGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAG 1737
Y T VGE+GVQLSGGQKQRIAIARA++K+PK+LLLDEATSALD+E+ER VQ ALD+ G
Sbjct: 1171 YDTSVGERGVQLSGGQKQRIAIARAILKDPKVLLLDEATSALDSESERIVQEALDRVMVG 1230
Query: 1738 RTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFY 1869
RTT+IVAHRLSTI D+I V K G + E G H L+ G Y
Sbjct: 1231 RTTVIVAHRLSTITGADKIAVIKNGVVAEEGRHGRLLRLPGGAY 1274
Score = 300 bits (768), Expect = 2e-79
Identities = 182/519 (35%), Positives = 285/519 (54%), Gaps = 4/519 (0%)
Frame = +1
Query: 2239 FVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRF 2418
F + I + F +C GE ++R + +LRQDI F+D L TG++ R
Sbjct: 92 FTYVAIGSGIAGFLQVSCWMVTGERQAARIRGLYLEAILRQDITFFD-LETSTGEVTERM 150
Query: 2419 ATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQM 2595
++D ++ + ++ L + T G I F GW + M +
Sbjct: 151 SSDTVLIQDAIGEKVGKFLQLLSTFLGGFIIAFARGWLLSLVMLSSIPPVALAAA-AMSI 209
Query: 2596 RFGKQIRDTQLL-EEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHT 2772
K +QL EAGK+ Q + IRTV S + + Y E+L+ + + +
Sbjct: 210 AISKLANRSQLAYAEAGKLVEQTIGSIRTVVSFTGERRATDKYNEFLKISYRSAVHQGAA 269
Query: 2773 YGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPD 2952
G ++F Y A + G+ + ++ + V AI +G ++ +
Sbjct: 270 MGLGIGSVMFIVFCSYGLAVWYGAKLIIEKGYTGGYIINVLMAIMSGAMALGQSSPCLNA 329
Query: 2953 VVKARLAASLLFYLIEHPTPIDSLSDSGIV-KPITGNISIRNVFFNYPTRKDTKVLQGFT 3129
++AA +F I ID+ SG+V + G++ ++V F+YP R + + GF+
Sbjct: 330 FASGQIAAYKMFATINREPEIDASDRSGLVLENFVGDVEFKDVHFSYPARPEQLIFTGFS 389
Query: 3130 LDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVS 3309
+ I +G T+ALVG SG GKST++ L+ERFY+ G +++DG N++ LN+S +R+++ +VS
Sbjct: 390 ISIPSGMTMALVGESGSGKSTVISLVERFYDPQSGEVLLDGVNMKLLNLSRIRQKIGLVS 449
Query: 3310 QEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSG 3489
QEP LF TI ENI YG ++ + +EI A +AN FI LP+G DT VGE GTQLSG
Sbjct: 450 QEPILFTTTIRENIEYG-KKDASEEEIRRAIVLANAAKFIDKLPNGLDTMVGEHGTQLSG 508
Query: 3490 GQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQ 3669
GQKQRIAIARA+++ P +LLLDEATSALD ESE +VQ+AL+ RT +++AHRLST++
Sbjct: 509 GQKQRIAIARAILKDPRILLLDEATSALDAESEHVVQDALNNIMVNRTTIIVAHRLSTVR 568
Query: 3670 NSDVIAIVSEGKIVEKGTHDELIRKSE-IYQKFCETQRI 3783
N+D I+++ G++VE+G H ELI+ S Y + + Q +
Sbjct: 569 NADTISVLHRGQLVEQGPHAELIKYSNGAYYQLLQLQEV 607
>gi|34913544|ref|NP_918119.1| putative multidrug resistance protein
[Oryza sativa (japonica cultivar-group)]
gi|20146377|dbj|BAB89158.1| putative multidrug resistance protein
[Oryza sativa (japonica cultivar-group)]
Length = 1184
Score = 775 bits (2001), Expect = 0.0
Identities = 444/1178 (37%), Positives = 662/1178 (55%), Gaps = 37/1178 (3%)
Frame = +1
Query: 349 YLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQ-TGNLTARLT 525
++ LGV S +Q++C+ ER ++R YLKAILRQ I +FDK+ TG L R++
Sbjct: 3 FIYLGVGAGLVSALQVSCWTITGERQAARIRALYLKAILRQDIAFFDKEMNTGQLVERMS 62
Query: 526 DDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSM 705
D +++ +G+K +Q+ + F G+ + F W + LVM+ P + ++GA MS+ M
Sbjct: 63 GDAFLIQDAIGEKAGKCIQLLSTFFGGFIIAFVRGWLLALVMLSSIPPVAVAGAIMSRLM 122
Query: 706 ATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMG 885
T Q Y AG + E+T +IRTV + NG K+ ++ + ++ ++ + + G
Sbjct: 123 VKLTIRMQAKYGDAGIVVEQTIGAIRTVVAFNGEKKAINTYNKFIKKAYESALQQGVING 182
Query: 886 IGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASF 1065
+G+G +SSY LA WYGS LI+ + ++ G++ V A++ + SLG A + +
Sbjct: 183 LGLGSIISVFFSSYGLAVWYGSRLIV-ERGYNGGIVINVIMAIMISAMSLGHATSSITAL 241
Query: 1066 GTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISL 1245
+GAA + R I P ID G + +++KGD+ K+V+F YPSR + V G SL
Sbjct: 242 AGGQGAAYRLFRTIERQPDIDACCTTGDIFEDVKGDVELKNVYFSYPSRPEHLVFDGFSL 301
Query: 1246 ELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQ 1425
++ +G ++ALVG SG GKST+++L++RFYDP G VLIDGVD+R +N+ S+R +IG+VSQ
Sbjct: 302 QVPSGTRMALVGESGSGKSTVISLVERFYDPQSGEVLIDGVDIRRINLGSIRRKIGLVSQ 361
Query: 1426 EPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQ 1605
EPVLF GTI ENI G E T +++ A ++ANA FI +LP+G T VGE+G+QLSGGQ
Sbjct: 362 EPVLFAGTIRENITYGKEDPTLEEINRAIELANAAKFIDKLPNGLETMVGERGIQLSGGQ 421
Query: 1606 KQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNV 1785
KQRIAIAR ++KNP+ILLLDEATSALD E+ER VQ AL++ RTTIIVAHRLST++N
Sbjct: 422 KQRIAIARVIIKNPRILLLDEATSALDMESERVVQEALNKVMLERTTIIVAHRLSTVKNA 481
Query: 1786 DRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXXEAGKDIEDTI--------- 1938
D I V + G +VE GSHEELM K Y A D D I
Sbjct: 482 DMISVLQHGKLVEQGSHEELMKKPEGSYCKLIHLQETRQEAVAPNDDPDMIIRNDFDSRI 541
Query: 1939 --SESAHSHLXXXXXXXXXXXXXXX----------------------IHQLAEEVEECKA 2046
S++ ++ I + +++ C+
Sbjct: 542 INSKTRSQNISFRKSTSKSSSFGHSGTHPFTSTCDLSDPMEVHDDQHIKETTDKMSNCQ- 600
Query: 2047 PPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANVYF 2226
S+ ++F N + + PVF ++ + ++ P ++ N
Sbjct: 601 EKASILRLFSLNKPEAFVLALGSITAAMHGVIFPVFGILVSSAIKMFYEPRSELLKNSRL 660
Query: 2227 WCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKL 2406
MF ++GI+ F+ T G G L ++R FK+++ Q+I+++D + +G +
Sbjct: 661 LGSMFPVLGISTFLLIPTEYFLFGLAGGKLVERIRSLTFKSVMYQEISWFDKPENSSGSI 720
Query: 2407 CTRFATDAPNV-RYVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYF 2583
R +TDA NV R V L + ++ TI I W+ Y
Sbjct: 721 GARLSTDALNVKRLVGDNLALNFQTLSTIISGFTIAMVANWKLALIITVVVPLVGFQAYA 780
Query: 2584 EMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKH 2763
+M G + E+A +VA++AV IRT+ S +++ Y + P ++
Sbjct: 781 QMMFLKGFNKNAKSMFEDATQVATEAVGGIRTITSFCAEQKVMNAYEKKCASPIIQGIRD 840
Query: 2764 AHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSF 2943
F FS + +F YA FY+G+ FV+Q +V+RVFF + I T++
Sbjct: 841 GVVGALGFGFSFLVFYFAYALCFYVGAKFVHQGTATFAEVFRVFFVLVLGINEISRTSAI 900
Query: 2944 IPDVVKARLAASLLFYLIEHPTPIDSLSDSGIV-KPITGNISIRNVFFNYPTRKDTKVLQ 3120
+ + + +F +++ + IDS +D G+V + G+I +NV F YP R + ++ +
Sbjct: 901 GSESRRVNESVVSVFKILDRKSKIDSSNDEGVVIASVRGDIEFQNVCFKYPLRPNVQIFK 960
Query: 3121 GFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVC 3300
+L I +GKT ALVG SG GKST++ LLERFY D G I+ DG + L +S LR Q+
Sbjct: 961 DLSLSIPSGKTAALVGESGSGKSTVISLLERFYEPDAGRILFDGVELETLKVSWLRLQIG 1020
Query: 3301 IVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQ 3480
+V+QEP LF+ TI NI YG + + +EI+ AA+ AN H FI GLPDGY+T VGE+G Q
Sbjct: 1021 LVAQEPVLFNDTIRANIAYGKQGDASEEEIIAAAEAANAHQFISGLPDGYNTIVGERGIQ 1080
Query: 3481 LSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLS 3660
LSGGQKQR+AIARA+++ P VLLLDEATSALD+ESE++VQEALD GRT +V+AHRLS
Sbjct: 1081 LSGGQKQRVAIARAVIKDPKVLLLDEATSALDSESERVVQEALDREVVGRTTVVVAHRLS 1140
Query: 3661 TIQNSDVIAIVSEGKIVEKGTHDELIR-KSEIYQKFCE 3771
TI+ +D+I ++ G IVEKG H+EL++ K IY E
Sbjct: 1141 TIKGADIIGVLENGTIVEKGRHEELMQIKGGIYSSLVE 1178
Score = 363 bits (932), Expect = 2e-98
Identities = 210/585 (35%), Positives = 326/585 (54%), Gaps = 7/585 (1%)
Frame = +1
Query: 136 DLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDE 315
+ +L G++ A +HG FP+ I++ +F E
Sbjct: 615 EAFVLALGSITAAMHGVIFPVFGILVSSAIKMFY-------------------------E 649
Query: 316 FNSEVVKYC----IYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQW 483
SE++K + VLG+ F + F +LV ++R K+++ Q+I W
Sbjct: 650 PRSELLKNSRLLGSMFPVLGISTFLLIPTEYFLFGLAGGKLVERIRSLTFKSVMYQEISW 709
Query: 484 FDKQQ--TGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMG 657
FDK + +G++ ARL+ D V+ +GD AL Q + ++G+ + +W + L++
Sbjct: 710 FDKPENSSGSIGARLSTDALNVKRLVGDNLALNFQTLSTIISGFTIAMVANWKLALIITV 769
Query: 658 FAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNA 837
PL+ + + + + A +A E IRT+ S ++ ++ +
Sbjct: 770 VVPLVGFQAYAQMMFLKGFNKNAKSMFEDATQVATEAVGGIRTITSFCAEQKVMNAYEKK 829
Query: 838 LEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVL 1017
GI +G GFS L Y +YAL F+ G+ ++ T +F VFF ++
Sbjct: 830 CASPIIQGIRDGVVGALGFGFSFLVFYFAYALCFYVGAK-FVHQGTATFAEVFRVFFVLV 888
Query: 1018 SGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHF 1197
G + + + +V ++++ KID + EG+++ +++GDI F++V F
Sbjct: 889 LGINEISRTSAIGSESRRVNESVVSVFKILDRKSKIDSSNDEGVVIASVRGDIEFQNVCF 948
Query: 1198 RYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLR 1377
+YP R ++ + K +SL + +G ALVG SG GKST+++LL+RFY+P GR+L DGV+L
Sbjct: 949 KYPLRPNVQIFKDLSLSIPSGKTAALVGESGSGKSTVISLLERFYEPDAGRILFDGVELE 1008
Query: 1378 EVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNE-HATHDQVVEACKMANANDFIKRLPD 1554
+ V LR QIG+V+QEPVLF+ TI NI G + A+ ++++ A + ANA+ FI LPD
Sbjct: 1009 TLKVSWLRLQIGLVAQEPVLFNDTIRANIAYGKQGDASEEEIIAAAEAANAHQFISGLPD 1068
Query: 1555 GYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQA 1734
GY T VGE+G+QLSGGQKQR+AIARA++K+PK+LLLDEATSALD+E+ER VQ ALD+
Sbjct: 1069 GYNTIVGERGIQLSGGQKQRVAIARAVIKDPKVLLLDEATSALDSESERVVQEALDREVV 1128
Query: 1735 GRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFY 1869
GRTT++VAHRLSTI+ D I V + G IVE G HEELM +G Y
Sbjct: 1129 GRTTVVVAHRLSTIKGADIIGVLENGTIVEKGRHEELMQIKGGIY 1173
Score = 322 bits (824), Expect = 6e-86
Identities = 190/521 (36%), Positives = 298/521 (56%), Gaps = 2/521 (0%)
Frame = +1
Query: 2239 FVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRF 2418
F+ +G+ + +C GE ++R K +LRQDIAF+D TG+L R
Sbjct: 3 FIYLGVGAGLVSALQVSCWTITGERQAARIRALYLKAILRQDIAFFDK-EMNTGQLVERM 61
Query: 2419 ATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQM 2595
+ DA ++ + + + + T G I F GW + G ++
Sbjct: 62 SGDAFLIQDAIGEKAGKCIQLLSTFFGGFIIAFVRGWLLALVMLSSIPPVAVAGAIMSRL 121
Query: 2596 RFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTY 2775
IR +AG V Q + IRTV + N +++ TY +++++ + + L+
Sbjct: 122 MVKLTIRMQAKYGDAGIVVEQTIGAIRTVVAFNGEKKAINTYNKFIKKAYESALQQGVIN 181
Query: 2776 GAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDV 2955
G S+ F Y A + GS + ++ V V AI +G+ TS I +
Sbjct: 182 GLGLGSIISVFFSSYGLAVWYGSRLIVERGYNGGIVINVIMAIMISAMSLGHATSSITAL 241
Query: 2956 VKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTKVLQGFTL 3132
+ AA LF IE ID+ +G I + + G++ ++NV+F+YP+R + V GF+L
Sbjct: 242 AGGQGAAYRLFRTIERQPDIDACCTTGDIFEDVKGDVELKNVYFSYPSRPEHLVFDGFSL 301
Query: 3133 DIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQ 3312
+ +G +ALVG SG GKST++ L+ERFY+ G ++IDG +IR +N+ S+R ++ +VSQ
Sbjct: 302 QVPSGTRMALVGESGSGKSTVISLVERFYDPQSGEVLIDGVDIRRINLGSIRRKIGLVSQ 361
Query: 3313 EPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGG 3492
EP LF TI ENI YG + T +EI A ++AN FI LP+G +T VGE+G QLSGG
Sbjct: 362 EPVLFAGTIRENITYG-KEDPTLEEINRAIELANAAKFIDKLPNGLETMVGERGIQLSGG 420
Query: 3493 QKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQN 3672
QKQRIAIAR ++++P +LLLDEATSALD ESE++VQEAL+ RT +++AHRLST++N
Sbjct: 421 QKQRIAIARVIIKNPRILLLDEATSALDMESERVVQEALNKVMLERTTIIVAHRLSTVKN 480
Query: 3673 SDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRIVESQ 3795
+D+I+++ GK+VE+G+H+EL++K E +C+ + E++
Sbjct: 481 ADMISVLQHGKLVEQGSHEELMKKPE--GSYCKLIHLQETR 519
>gi|50546639|ref|XP_500789.1| hypothetical protein [Yarrowia
lipolytica]
gi|49646655|emb|CAG83040.1| unnamed protein product [Yarrowia
lipolytica CLIB99]
Length = 1304
Score = 775 bits (2001), Expect = 0.0
Identities = 466/1247 (37%), Positives = 686/1247 (54%), Gaps = 23/1247 (1%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F Y D L++ G V A G P+ I+ G MT F + FV G
Sbjct: 76 LFRYADKFDFFLIMVGLVMAAAAGVCLPIFTIIFGSMTNEF----TNFFVYGA------- 124
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
S + F S + + +Y++ L V F T+ ++ ERL ++R NYLKAILRQ
Sbjct: 125 ----SKEHFQSRINHFALYFVYLAVATFGTTAIKTYITVERGERLTARIRANYLKAILRQ 180
Query: 472 QIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVM 651
I +FDK G +T R+T D ++EG+ +K L+V A+F+ +GF +T +M
Sbjct: 181 NIGYFDKLGAGEVTNRITSDTNLIQEGISEKLGLIVSAIASFITALVIGFIKQAKLTGIM 240
Query: 652 MGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFY 831
+ + LS S + T++ E + +IAEE FSSIR + + R ++++
Sbjct: 241 LSTVFALALSMGICSTFLVKYTKLALEDDSACSSIAEEAFSSIRNIVAFGSQSRMVEKYN 300
Query: 832 NALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFA 1011
L + K + + VG +Y YALA W GS L+ T G + TV A
Sbjct: 301 VPLASSLHNYLRKNISLAVMVGCLWSLIYIKYALALWEGSRLVAWGET-QVGNVTTVLMA 359
Query: 1012 VLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDV 1191
++ G+ LGG P+L S G A + + I+ P+ID EG + ++KG I F +V
Sbjct: 360 LMIGAFELGGVAPNLESVGVAIASGKKIFGTIDRVPEIDTQE-EGEKIPDIKGHIVFDNV 418
Query: 1192 HFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVD 1371
FRYPSR + +L+ +LE+ G +ALVG+SG GKST++ LL+RFY P G + IDG +
Sbjct: 419 DFRYPSRPKVQILEDFNLEVLPGQTVALVGASGSGKSTLIGLLERFYQPLSGLITIDGYN 478
Query: 1372 LREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGN-----EHATHDQVVE----ACKMAN 1524
L +++V LR+ I +VSQEP LF+ TIYENI G EHA ++ +E AC+ AN
Sbjct: 479 LLDLDVKWLRQHISLVSQEPTLFNCTIYENITFGLIGTQWEHADDEKKMELVEHACRQAN 538
Query: 1525 ANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAERE 1704
A DFI+ L DG T VGE G+ LSGGQKQRIAIARA++ NP ILLLDEATSALDT++E
Sbjct: 539 AWDFIQLLTDGINTNVGESGMLLSGGQKQRIAIARAIISNPPILLLDEATSALDTKSEGI 598
Query: 1705 VQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXX 1884
VQ ALD+A RTTI++AHRLSTI+N +I V G I+E G+H EL++KQG++Y +
Sbjct: 599 VQEALDKASENRTTIVIAHRLSTIKNASKIVVMSKGEIIEQGTHAELLAKQGMYYGLVDA 658
Query: 1885 XXXXXX--XXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKAPPTS 2058
++ D ED + + + +
Sbjct: 659 QKLTEARPGQKSSSDGEDAPLLIQEDDMKIGKSTTNKSLSSQILANKEKPDRDKHLSIAG 718
Query: 2059 MFKIF-KFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQ---MQANVYF 2226
M K+ K+N ++ + + P AL++A + + D M++ +
Sbjct: 719 MVKLLAKYNRNERPFLYVGSFAALINGAGYPALALLFASAMQAFMVSPDMYHWMRSEMNK 778
Query: 2227 WCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKL 2406
+ G ++G+ + +F CLG C E L +R F +LLR D+AF+D+ + TG L
Sbjct: 779 YSGFLFMVGMIELMAYFVQIYCLGWCSEHLVRNIRHSVFSHLLRMDVAFHDEDDNTTGSL 838
Query: 2407 CTRFATDAPNVRYV-FTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYF 2583
+ + DA V+ + +L+S+ TI + I Y W+ G+F
Sbjct: 839 TSTLSKDAQYVQGLGGATFGQILSSLCTIVIGVIIAICYTWRLGLVCTACVPLIIAAGFF 898
Query: 2584 EMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLR--EPFNTNL 2757
+ +R ++ E++ A +A IRTV +L R++ + Y +YL E +
Sbjct: 899 RFWILTHLNLRGKKVYEQSASYACEATTSIRTVVTLTRED---YVYNDYLHKVESQVADS 955
Query: 2758 KHAHTYGA-VFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNT 2934
A+ Y A +FA SQSL + A F+ GS + + + F ++ F Q G+
Sbjct: 956 ARANIYSATLFAASQSLNLLISALGFWYGSTLMKDGIIDTNKFFVAFVSVVFGCQSAGSI 1015
Query: 2935 TSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIV---KPITGNISIRNVFFNYPTRKD 3105
SF PD+ KA+ A + ++ +D S GI+ + G+IS +V F YPTR
Sbjct: 1016 FSFTPDMGKAKTATQNIANMLAVLPELDVDSTEGIILDHDNVRGDISFEDVRFRYPTRPQ 1075
Query: 3106 TKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSL 3285
+L+G L+IK G+ VALVG SGCGKST + L+ERFY+ G + +DG +IR++NI+S
Sbjct: 1076 VPILRGLNLNIKKGQYVALVGSSGCGKSTTIALIERFYDVLSGAVKLDGVDIRDININSY 1135
Query: 3286 REQVCIVSQEPTLFDCTIGENICYGTNR-NVTYQEIVEAAKMANIHNFILGLPDGYDTHV 3462
R + +V QEP LF T+ ENI G+ R +VT +E++EAA+MANIH+F++ LPDGYDT+
Sbjct: 1136 RSCISLVQQEPVLFSGTVRENILLGSLRDDVTEEEMIEAAEMANIHSFVMSLPDGYDTYC 1195
Query: 3463 GEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLV 3642
G KG+ LSGGQKQR+AIARAL+R+P +LLLDEATSALD+ESEKIVQ ALD A +GRT +
Sbjct: 1196 GSKGSLLSGGQKQRVAIARALIRNPKILLLDEATSALDSESEKIVQAALDQAAKGRTTIA 1255
Query: 3643 IAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRI 3783
+AHRLSTIQN+D+I + EG+++E GTH EL+ Y + + Q +
Sbjct: 1256 VAHRLSTIQNADIIYVFEEGRVLESGTHQELLANKSKYYELVKLQAL 1302
Score = 306 bits (785), Expect = 2e-81
Identities = 198/567 (34%), Positives = 302/567 (52%), Gaps = 17/567 (2%)
Frame = +1
Query: 2146 PVFALVYAEIFN------VYSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCG 2307
P+F +++ + N VY + Q+ + + FV + + F G
Sbjct: 103 PIFTIIFGSMTNEFTNFFVYGASKEHFQSRINHFALYFVYLAVATFGTTAIKTYITVERG 162
Query: 2308 ESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIV 2484
E LT ++R K +LRQ+I ++D L G G++ R +D ++ + +L +++++I
Sbjct: 163 ERLTARIRANYLKAILRQNIGYFDKL--GAGEVTNRITSDTNLIQEGISEKLGLIVSAIA 220
Query: 2485 TICGALGIGFYYGWQXXXXXXXX--XXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQ 2658
+ AL IGF + MG +++ K + +A +
Sbjct: 221 SFITALVIGFIKQAKLTGIMLSTVFALALSMGICSTFLVKYTKLALEDD--SACSSIAEE 278
Query: 2659 AVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYL 2838
A IR + + Q + Y L + L+ + + SLI+ YA A +
Sbjct: 279 AFSSIRNIVAFGSQSRMVEKYNVPLASSLHNYLRKNISLAVMVGCLWSLIYIKYALALWE 338
Query: 2839 GSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPID 3018
GS V Q +V V A+ +G + V A + +F I+ ID
Sbjct: 339 GSRLVAWGETQVGNVTTVLMALMIGAFELGGVAPNLESVGVAIASGKKIFGTIDRVPEID 398
Query: 3019 SLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIM 3198
+ + + I G+I NV F YP+R ++L+ F L++ G+TVALVG SG GKST++
Sbjct: 399 TQEEGEKIPDIKGHIVFDNVDFRYPSRPKVQILEDFNLEVLPGQTVALVGASGSGKSTLI 458
Query: 3199 GLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGT----- 3363
GLLERFY G+I IDG N+ +L++ LR+ + +VSQEPTLF+CTI ENI +G
Sbjct: 459 GLLERFYQPLSGLITIDGYNLLDLDVKWLRQHISLVSQEPTLFNCTIYENITFGLIGTQW 518
Query: 3364 --NRNVTYQEIVE-AAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRS 3534
+ E+VE A + AN +FI L DG +T+VGE G LSGGQKQRIAIARA++ +
Sbjct: 519 EHADDEKKMELVEHACRQANAWDFIQLLTDGINTNVGESGMLLSGGQKQRIAIARAIISN 578
Query: 3535 PSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVE 3714
P +LLLDEATSALDT+SE IVQEALD A + RT +VIAHRLSTI+N+ I ++S+G+I+E
Sbjct: 579 PPILLLDEATSALDTKSEGIVQEALDKASENRTTIVIAHRLSTIKNASKIVVMSKGEIIE 638
Query: 3715 KGTHDELIRKSEIYQKFCETQRIVESQ 3795
+GTH EL+ K +Y + Q++ E++
Sbjct: 639 QGTHAELLAKQGMYYGLVDAQKLTEAR 665
>gi|25407562|pir||H85202 hypothetical protein AT4g18050 [imported] -
Arabidopsis thaliana
gi|7268557|emb|CAB78807.1| multidrug resistance
protein/P-glycoprotein-like [Arabidopsis thaliana]
Length = 1323
Score = 775 bits (2000), Expect = 0.0
Identities = 457/1266 (36%), Positives = 691/1266 (54%), Gaps = 52/1266 (4%)
Frame = +1
Query: 94 KLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVD 273
K++ + +F + D++L+ GT+AA +G P + ++ G + F
Sbjct: 15 KVSFFKLFSFADKTDVVLMTVGTIAAAGNGLTQPFMTLIFGQLINAF------------G 62
Query: 274 NVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYL 453
+P+ +V EV K + ++ L V +++Q++C+ ER +R YL
Sbjct: 63 TTDPDHMV--------REVWKVAVKFIYLAVYSCVVAFLQVSCWMVTGERQSATIRGLYL 114
Query: 454 KAILRQQIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYS 630
K ILRQ I +FD + TG + R++ D +++ +G+K Q+ FL G+ + F+
Sbjct: 115 KTILRQDIGYFDTETNTGEVIGRMSGDTILIQDAMGEKVGKFTQLLCTFLGGFAIAFYKG 174
Query: 631 WSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHK 810
+ V+ PLIV++GA MS M+ Q YA AG + E+T +IRTV + G K
Sbjct: 175 PLLAGVLCSCIPLIVIAGAAMSLIMSKMAGRGQVAYAEAGNVVEQTVGAIRTVVAFTGEK 234
Query: 811 RELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGL 990
+ +++ + LE+ +T + + G G+G ++ SY LA WYG+ LI+ + ++ G
Sbjct: 235 QATEKYESKLEIAYKTVVQQGLISGFGLGTMLAVIFCSYGLAVWYGAKLIM-EKGYNGGQ 293
Query: 991 IFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKG 1170
+ V FAVL+G SLG P L +F R AA + I PKID Y + G ++++++G
Sbjct: 294 VINVIFAVLTGGMSLGQTSPSLNAFAAGRAAAFKMFETIKRSPKIDAYDMSGSVLEDIRG 353
Query: 1171 DISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGR 1350
DI KDV+FRYP+R D+ + G SL + G +ALVG SG GKST+++L++RFYDP G+
Sbjct: 354 DIELKDVYFRYPARPDVQIFAGFSLFVPNGKTVALVGQSGSGKSTVISLIERFYDPESGQ 413
Query: 1351 VLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAN 1530
VLID +DL+++ + +R +IG+VSQEPVLF TI ENI G E AT ++ A ++ANA
Sbjct: 414 VLIDNIDLKKLQLKWIRSKIGLVSQEPVLFATTIKENIAYGKEDATDQEIRTAIELANAA 473
Query: 1531 DFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQ 1710
FI +LP G T VGE G Q+SGGQKQR+AIARA++KNPKILLLDEATSALD E+ER VQ
Sbjct: 474 KFIDKLPQGLDTMVGEHGTQMSGGQKQRLAIARAILKNPKILLLDEATSALDAESERIVQ 533
Query: 1711 GALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELM-SKQGIFYDM---- 1875
AL + RTT++VAHRL+TIR D I V G IVE G+H+E++ +G + +
Sbjct: 534 DALVNLMSNRTTVVVAHRLTTIRTADVIAVVHQGKIVEKGTHDEMIQDPEGAYSQLVRLQ 593
Query: 1876 --TXXXXXXXXXXEAGKDIE------------DTISESAHSHLXXXXXXXXXXXXXXXIH 2013
+ E D+E ++S ++ S ++
Sbjct: 594 EGSKEEATESERPETSLDVERSGSLRLSSAMRRSVSRNSSSSRHSFSLASNMFFPGVNVN 653
Query: 2014 Q---LAEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNV 2184
Q + +E + S+ ++ N ++ +V P+F L+ + N+
Sbjct: 654 QTDEMEDEENNVRHKKVSLKRLAHLNKPEIPVLVLGSIAAMVHGTVFPIFGLLLSSSINM 713
Query: 2185 YSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQD 2364
+ PA ++ + +FW +++ +G+T FV G G L ++R F ++ Q+
Sbjct: 714 FYEPAKILKKDSHFWALIYIALGLTNFVMIPVPNYFFGIAGGKLIKRIRSMCFDKVVHQE 773
Query: 2365 IAFYDDLRHG---------------------------TGKLCTRFATDAPNVR-YVFTRL 2460
I+++DD + +L +TDA VR V L
Sbjct: 774 ISWFDDTANSRYYNFIYIINRRILYVLILIFICVLLPPVRLERECSTDASTVRSLVGDAL 833
Query: 2461 PVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEA 2640
+++ +I T+ L I F W + GY + + G + EEA
Sbjct: 834 ALIVQNIATVTTGLIIAFTANWILALIVLALSPFIVIQGYAQTKFLTGFSADAKAMYEEA 893
Query: 2641 GKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMY 2820
+VA+ AV IRTV S +E+ Y + P ++ GA F FS ++ +
Sbjct: 894 SQVANDAVSSIRTVASFCAEEKVMDLYQQKCDGPKKNGVRLGLLSGAGFGFSFFFLYCIN 953
Query: 2821 AAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIE 3000
F G+ + +V++VFFA++ + T++ PD KA+ +A+ +F +++
Sbjct: 954 CVCFVSGAGLIQIGKATFGEVFKVFFALTIMAIGVSQTSAMAPDSNKAKDSAASIFDILD 1013
Query: 3001 HPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSG 3177
IDS SD G ++ + G+I R+V F YP R D ++ + L I +GKTVALVG SG
Sbjct: 1014 STPKIDSSSDEGTTLQNVNGDIEFRHVSFRYPMRPDVQIFRDLCLTIPSGKTVALVGESG 1073
Query: 3178 CGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICY 3357
GKST++ ++ERFYN D G I+ID I+ +S LR+Q+ +VSQEP LF+ TI NI Y
Sbjct: 1074 SGKSTVISMIERFYNPDSGKILIDQVEIQTFKLSWLRQQMGLVSQEPILFNETIRSNIAY 1133
Query: 3358 GTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSP 3537
G T +EI+ AAK AN HNFI LP GYDT VGE+G QLSGGQKQRIAIARA+++ P
Sbjct: 1134 GKTGGATEEEIIAAAKAANAHNFISSLPQGYDTSVGERGVQLSGGQKQRIAIARAILKDP 1193
Query: 3538 SVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEK 3717
+LLLDEATSALD ESE++VQ+ALD RT +V+AHRL+TI+N+DVIA+V G I EK
Sbjct: 1194 KILLLDEATSALDAESERVVQDALDRVMVNRTTVVVAHRLTTIKNADVIAVVKNGVIAEK 1253
Query: 3718 GTHDEL 3735
G H+ L
Sbjct: 1254 GRHETL 1259
Score = 321 bits (823), Expect = 7e-86
Identities = 204/570 (35%), Positives = 300/570 (51%), Gaps = 5/570 (0%)
Frame = +1
Query: 2056 SMFKIFKFNGDKVGWXXXXXXXXXXXXS--VTPVFALVYAEIFNVY-SLPADQMQANVYF 2226
S FK+F F DK + P L++ ++ N + + D M V+
Sbjct: 17 SFFKLFSF-ADKTDVVLMTVGTIAAAGNGLTQPFMTLIFGQLINAFGTTDPDHMVREVWK 75
Query: 2227 WCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKL 2406
F+ + + V F +C GE + +R K +LRQDI ++D TG++
Sbjct: 76 VAVKFIYLAVYSCVVAFLQVSCWMVTGERQSATIRGLYLKTILRQDIGYFDT-ETNTGEV 134
Query: 2407 CTRFATDAPNVRYVF-TRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYF 2583
R + D ++ ++ + T G I FY G + G
Sbjct: 135 IGRMSGDTILIQDAMGEKVGKFTQLLCTFLGGFAIAFYKGPLLAGVLCSCIPLIVIAGAA 194
Query: 2584 EMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKH 2763
+ R EAG V Q V IRTV + ++Q Y L + T ++
Sbjct: 195 MSLIMSKMAGRGQVAYAEAGNVVEQTVGAIRTVVAFTGEKQATEKYESKLEIAYKTVVQQ 254
Query: 2764 AHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSF 2943
G ++IF Y A + G+ + ++ V V FA+ G +G T+
Sbjct: 255 GLISGFGLGTMLAVIFCSYGLAVWYGAKLIMEKGYNGGQVINVIFAVLTGGMSLGQTSPS 314
Query: 2944 IPDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTKVLQ 3120
+ R AA +F I+ ID+ SG +++ I G+I +++V+F YP R D ++
Sbjct: 315 LNAFAAGRAAAFKMFETIKRSPKIDAYDMSGSVLEDIRGDIELKDVYFRYPARPDVQIFA 374
Query: 3121 GFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVC 3300
GF+L + GKTVALVG SG GKST++ L+ERFY+ + G ++ID +++ L + +R ++
Sbjct: 375 GFSLFVPNGKTVALVGQSGSGKSTVISLIERFYDPESGQVLIDNIDLKKLQLKWIRSKIG 434
Query: 3301 IVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQ 3480
+VSQEP LF TI ENI YG + T QEI A ++AN FI LP G DT VGE GTQ
Sbjct: 435 LVSQEPVLFATTIKENIAYG-KEDATDQEIRTAIELANAAKFIDKLPQGLDTMVGEHGTQ 493
Query: 3481 LSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLS 3660
+SGGQKQR+AIARA++++P +LLLDEATSALD ESE+IVQ+AL RT +V+AHRL+
Sbjct: 494 MSGGQKQRLAIARAILKNPKILLLDEATSALDAESERIVQDALVNLMSNRTTVVVAHRLT 553
Query: 3661 TIQNSDVIAIVSEGKIVEKGTHDELIRKSE 3750
TI+ +DVIA+V +GKIVEKGTHDE+I+ E
Sbjct: 554 TIRTADVIAVVHQGKIVEKGTHDEMIQDPE 583
>gi|39587990|emb|CAE57221.1| Hypothetical protein CBG00083
[Caenorhabditis briggsae]
Length = 1301
Score = 773 bits (1995), Expect = 0.0
Identities = 464/1268 (36%), Positives = 695/1268 (54%), Gaps = 46/1268 (3%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F + D +LLI G V ++I G P+LAI+ G +T V L
Sbjct: 59 LFRFATPFDYILLIIGVVTSIISGVSQPVLAIISGRLTNVLLVVD--------------- 103
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
P+S EF ++ ++ +L LG+ + + Q CF+ R++ ++R Y+ +ILRQ
Sbjct: 104 --PLS-KEFKNKAMENVYIFLGLGIFVSINDFCQYMCFQRVCSRMMTQMRNRYISSILRQ 160
Query: 472 QIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVM 651
WFDK +G +T RL D++ER+++G+GDK +L++ + L + Y W + L+M
Sbjct: 161 NAGWFDKNLSGTITTRLNDNMERIQDGVGDKLGVLIRGISMVLTSVIISLVYEWRLALMM 220
Query: 652 MGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFY 831
+G P+ + +S+ + T E E +AGAIAEE+ +RT+ + NG + + ++
Sbjct: 221 VGLIPVSTICMTLLSRFLEKSTGEELEKVGIAGAIAEESLMGVRTIQAFNGQEEMVAKYE 280
Query: 832 NALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFA 1011
L G++ I+ + G G + + YG L+ G +F + A
Sbjct: 281 KHLNSGKRHAIIGGFWSGFFGGMFFFWLLAFMGCGILYGGYLLKVGIIKSPGDVFIIIMA 340
Query: 1012 VLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDV 1191
+L G+ LG PHL AR AA+++ + I+ PKIDPYS G +D + G ++F++V
Sbjct: 341 MLLGAYFLGLISPHLMVLLNARVAAASIYKTIDRVPKIDPYSKAGKKLDRVVGKVTFRNV 400
Query: 1192 HFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVD 1371
HFRYP+RK+ VL G+ L ++ G +ALVG SGCGKST V LL R Y+P G V IDGVD
Sbjct: 401 HFRYPTRKEAKVLNGLDLTVEPGTSVALVGHSGCGKSTSVGLLTRLYEPEDGSVQIDGVD 460
Query: 1372 LREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLP 1551
+R++N+ LR +GIV QEP+LF+ TI+ N+ +GN AT ++++E CKMANA+DFIK++P
Sbjct: 461 VRDLNMDWLRNIVGIVQQEPILFNDTIHNNLLIGNPDATREKMIEVCKMANAHDFIKKMP 520
Query: 1552 DGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQ 1731
GY T +G+ GVQLSGGQKQR+AIAR L+++PKILLLDEATSALD ++E VQ AL+ A
Sbjct: 521 KGYDTLIGDGGVQLSGGQKQRVAIARTLIRDPKILLLDEATSALDAQSESVVQSALNNAA 580
Query: 1732 AGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYD------------- 1872
GRTTI++AHRLSTIR D+I F+ G IVE+G+H EL++ G +Y+
Sbjct: 581 RGRTTIMIAHRLSTIREADKIVFFEKGVIVEAGNHGELVALGGRYYNLVKAQQFKQDPED 640
Query: 1873 ------------------MTXXXXXXXXXXEAGKDIED-----TISESAHSHLXXXXXXX 1983
M +G+ D T++ +
Sbjct: 641 IELEAEQEDQFDEFEKPTMFTRQVSTRSSRSSGRSGSDEFRRGTLANHSFDRFRKPSHVP 700
Query: 1984 XXXXXXXXIHQLAEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALV 2163
+ ++ E +E+ + IFK G+ P FAL+
Sbjct: 701 TAEDEAFAL-KVKETMEKDEEVTAGYLDIFKNAHGNYGYMFIGLVAALIRGLDLPAFALL 759
Query: 2164 YAEIFNVYSLPA------DQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMK 2325
+ +F + + +V CG V +GI FF T + E+L ++
Sbjct: 760 LSWVFEGFEFVPYGGKMMHRFVMSVIAHCG--VGLGIWFFQTLSTVMFAI--VSENLGVR 815
Query: 2326 LRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVFT-RLPVVLASIVTICGAL 2502
R +AF+NLL QD A++D+ H G L TR A D P+V+ V R+ V+ + + +
Sbjct: 816 FRVDAFRNLLYQDSAYFDNPAHAPGSLITRLAADPPSVKAVVDGRMMQVIYAFSAVVACV 875
Query: 2503 GIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLE--EAGKVASQAVEHIR 2676
IGF Y WQ G+ + F I + ++ +AGKVA + +E+++
Sbjct: 876 TIGFIYCWQVAILGTSLIFFL---GFVMCGLAFKITILAVEHMQNDDAGKVAIEIIENVK 932
Query: 2677 TVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVN 2856
T+ L R ++F +Y ++ T L+ + ++ +Q+ +++M F L +N
Sbjct: 933 TIQLLTRTKRFLNSYENESKKRKTTELRKSVFEAINYSITQNFMYYMSCFCFALAIRVIN 992
Query: 2857 QQAMQPID-VYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDS 3033
+ QP+D +R A+ C + I + F P V A+ AA +F LI + P +
Sbjct: 993 E-GDQPVDKTFRSLMAMMLCCEGIILSAQFFPQFVGAKSAAGQMFNLI-YRKPQTGDVKT 1050
Query: 3034 GIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLER 3213
G I GNI NV F+YP R V++ G+TVA+VG SG GKST + +LER
Sbjct: 1051 GSQPEIRGNILFENVKFSYPQRPHQPVMKTLQWTALRGQTVAIVGPSGSGKSTCISMLER 1110
Query: 3214 FYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIV 3393
FY+ G + IDG +IR +++ LR Q+ +V QEP LF TI ENIC G ++V ++I
Sbjct: 1111 FYDVTGGALRIDGQDIRTMSLYHLRTQMALVGQEPRLFVGTIRENICLGL-KDVPLEKIN 1169
Query: 3394 EAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSAL 3573
+A ++AN + F+ LP G DT VGE+G QLSGGQKQRIAIARALVR P +LLLDEATSAL
Sbjct: 1170 QALELANANRFLGNLPAGIDTEVGERGGQLSGGQKQRIAIARALVRDPKILLLDEATSAL 1229
Query: 3574 DTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEI 3753
D+ESEK VQEALD A++GRTC+ IAHRLS+IQNSD+I + +G++ E GTH+EL+
Sbjct: 1230 DSESEKAVQEALDRAREGRTCITIAHRLSSIQNSDLIVYIDDGRVQEAGTHNELMHMKGK 1289
Query: 3754 YQKFCETQ 3777
Y + + Q
Sbjct: 1290 YFELIKKQ 1297
Score = 305 bits (781), Expect = 5e-81
Identities = 194/561 (34%), Positives = 302/561 (53%), Gaps = 16/561 (2%)
Frame = +1
Query: 2146 PVFALVYAEIFNVYSLP-------ADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRC 2304
PV A++ + NV + ++ NVY + G+ + + I F + C R
Sbjct: 86 PVLAIISGRLTNVLLVVDPLSKEFKNKAMENVYIFLGLGIFVSINDFCQYM----CFQRV 141
Query: 2305 GESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASI 2481
+ ++R ++LRQ+ ++D ++ +G + TR + ++ V +L V++ I
Sbjct: 142 CSRMMTQMRNRYISSILRQNAGWFD--KNLSGTITTRLNDNMERIQDGVGDKLGVLIRGI 199
Query: 2482 VTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEE--AGKVAS 2655
+ ++ I Y W+ + + RF ++ +L + AG +A
Sbjct: 200 SMVLTSVIISLVYEWRLALMMVGLIPVSTI--CMTLLSRFLEKSTGEELEKVGIAGAIAE 257
Query: 2656 QAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFF-----MY 2820
+++ +RT+ + N QE+ Y ++L N+ +HA G F + FF M
Sbjct: 258 ESLMGVRTIQAFNGQEEMVAKYEKHL----NSGKRHAIIGGFWSGFFGGMFFFWLLAFMG 313
Query: 2821 AAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIE 3000
Y G + P DV+ + A+ +G + + ++ AR+AA+ ++ I+
Sbjct: 314 CGILYGGYLLKVGIIKSPGDVFIIIMAMLLGAYFLGLISPHLMVLLNARVAAASIYKTID 373
Query: 3001 HPTPIDSLSDSGI-VKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSG 3177
ID S +G + + G ++ RNV F YPTRK+ KVL G L ++ G +VALVGHSG
Sbjct: 374 RVPKIDPYSKAGKKLDRVVGKVTFRNVHFRYPTRKEAKVLNGLDLTVEPGTSVALVGHSG 433
Query: 3178 CGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICY 3357
CGKST +GLL R Y + G + IDG ++R+LN+ LR V IV QEP LF+ TI N+
Sbjct: 434 CGKSTSVGLLTRLYEPEDGSVQIDGVDVRDLNMDWLRNIVGIVQQEPILFNDTIHNNLLI 493
Query: 3358 GTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSP 3537
G N + T ++++E KMAN H+FI +P GYDT +G+ G QLSGGQKQR+AIAR L+R P
Sbjct: 494 G-NPDATREKMIEVCKMANAHDFIKKMPKGYDTLIGDGGVQLSGGQKQRVAIARTLIRDP 552
Query: 3538 SVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEK 3717
+LLLDEATSALD +SE +VQ AL+ A +GRT ++IAHRLSTI+ +D I +G IVE
Sbjct: 553 KILLLDEATSALDAQSESVVQSALNNAARGRTTIMIAHRLSTIREADKIVFFEKGVIVEA 612
Query: 3718 GTHDELIRKSEIYQKFCETQR 3780
G H EL+ Y + Q+
Sbjct: 613 GNHGELVALGGRYYNLVKAQQ 633
>gi|422285|pir||S30327 multidrug resistance protein 1 - Entamoeba
histolytica
gi|158971|gb|AAA29112.1| P-glycoprotein-1
Length = 1302
Score = 766 bits (1977), Expect = 0.0
Identities = 469/1272 (36%), Positives = 697/1272 (53%), Gaps = 57/1272 (4%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F Y +++LLI G + ++ G PLL I+ G + F+ +N G
Sbjct: 38 LFRYAGVFEIILLIIGIIGSIGVGCLNPLLMILTGDVVDTFVNGENFS--------KEGG 89
Query: 292 LVPISLDEFNSEV---VKYCIYYLVLGVLMF-----FTSYVQIACFESYAERLVHKLRQN 447
+ I+ +E N E+ + I LVL +L F ++Q CF +E K+R
Sbjct: 90 SIKITTEEMNYEIMNSISDTINKLVLKMLYFAIGNMVAGFLQTICFFVLSEYQGIKIRSL 149
Query: 448 YLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFY 627
Y KA+LRQ WFD +TG LT+++ +D++++++G+ KF L Q F++F+ GY +GF
Sbjct: 150 YFKALLRQDPGWFDCHKTGELTSKIINDIQKIQDGMSLKFGRLFQTFSSFITGYLIGFIK 209
Query: 628 SWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGH 807
W +TLV++ P I++S + S T + ++ A +IAE+T +IRTVHSL
Sbjct: 210 CWDLTLVVLCMFPFIMVSMMGLGMSAGIFTMKSHKPFSEACSIAEQTIGNIRTVHSLTQE 269
Query: 808 KRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDR- 984
+ + + + + I K +G G+G + SS AL WYG+ ++ D
Sbjct: 270 RSFCESYNTKIMETDKYNIKKSIGIGTGLGCMMFFIMSSNALGSWYGNFVVRGKGGSDNV 329
Query: 985 --GLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVD 1158
G + TVF +VL + SL + +A+ AA V + I+ P ID S+ G
Sbjct: 330 KAGTVLTVFMSVLLATQSLSQISTPINILNSAKVAAFNVYQTIDRIPDIDCQSIGGECPT 389
Query: 1159 NMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDP 1338
G+I F+DV F YP+R HVLKG+ LE+K G IALVG+SGCGKST + L+QR YDP
Sbjct: 390 ECNGNIRFEDVQFVYPTRLSHHVLKGLDLEIKKGQTIALVGASGCGKSTTIQLIQRNYDP 449
Query: 1339 TKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMG-NEHAT--HDQVVEA 1509
GRV +DG D+RE+N+ LR QIG+V QEPVLF GTI ENI +G E AT ++++E
Sbjct: 450 NGGRVTLDGKDIRELNIKWLRNQIGLVGQEPVLFAGTIRENIMLGAKEGATPSEEEMIEC 509
Query: 1510 CKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDT 1689
KMANA+DFI +LP+GY T +GEKG LSGGQKQRIAIARAL++NP ILLLDEATSALDT
Sbjct: 510 AKMANAHDFISKLPEGYDTIIGEKGALLSGGQKQRIAIARALIRNPSILLLDEATSALDT 569
Query: 1690 EAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFY 1869
++E+ VQ AL++A GRTTIIVAHRL+T+RN D+I VF G I+E G H+ELM +G +Y
Sbjct: 570 QSEKIVQEALEKASKGRTTIIVAHRLTTVRNADKICVFHQGEIIEQGKHQELMDLKGTYY 629
Query: 1870 DM-------------TXXXXXXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXI 2010
+ T + K++E+ E + H +
Sbjct: 630 GLVKRQSMEEEVDQETVENDLKKFREQEDKEVENISLEQTNLH-----------NENSIV 678
Query: 2011 HQLAEEV--EECKAPPTSMFKIFK--FNGDKVGWX--XXXXXXXXXXXSVTPVFALVYAE 2172
Q+ +E E+ K ++ F +F+ +N K + + P ++L + +
Sbjct: 679 KQIKQEYKEEQKKLKHSNRFVLFRVIWNNYKHEYIFCTLGLIGGIGAGAAFPFYSLNFVD 738
Query: 2173 IFNVYSLP------ADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRF 2334
+ V D+ ++ C + + +GI + FF GE + ++R
Sbjct: 739 LIRVLMKLHPGINLTDEQANSILRSCMIIICIGIITMISFFCYVGLFMAAGEKMIGRIRR 798
Query: 2335 EAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVFT-RLPVVLASIVTICGALGIG 2511
+ +++ Q+++++D + G + T+ +D +++ + R+ ++ + T+ GIG
Sbjct: 799 RFYYSIMHQNVSWFDRRENMVGAVTTKLTSDPTSLQGISAERVGDIIEIMSTVGFGFGIG 858
Query: 2512 FYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSL 2691
Y+ W+ + Q+ E+ G + VE ++T SL
Sbjct: 859 LYFSWKLSLCILAVFPIISFFMFINGQLNSKNAAPAKAAYEQCGVTLVEVVEAMKTAQSL 918
Query: 2692 NRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIF----VNQ 2859
+++ F Y L+ P +K A + L F + A +YLG F +N
Sbjct: 919 GKEDYFSQKYNNDLQIPKRGIIKWGPLLSITNAITNLLTFSINAYGYYLGICFMKKTINY 978
Query: 2860 QAMQPI----------DVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPT 3009
Q P D+ + I+ + +PDV KA AA ++ +I+
Sbjct: 979 QQDVPNFVDEIIDTFGDIQKALMTINSATTSFAQIGNVLPDVGKAVGAAKSIYNIIDRKP 1038
Query: 3010 PIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGK 3186
ID S+ G + G I +N+ F YPTR D +VL+G + + GKT+ALVG SGCGK
Sbjct: 1039 SIDCYSEEGETFNDVKGEIEFKNIHFRYPTRADNEVLKGISFKAEQGKTIALVGASGCGK 1098
Query: 3187 STIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTN 3366
ST + L+ERFY+ G +++DG NI++LNI LR Q+ +V QEP LF ++ +NI G
Sbjct: 1099 STTIQLIERFYDPTSGEVLLDGHNIKDLNIHFLRNQIGLVGQEPVLFAESVIDNIKRGVP 1158
Query: 3367 RNV--TYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPS 3540
V + ++I AAKMAN H+FI +P+GY+T VG++G+QLSGGQKQRIAIARAL+R+P
Sbjct: 1159 EGVEVSNEQIYAAAKMANAHDFISAMPEGYNTMVGDRGSQLSGGQKQRIAIARALIRNPK 1218
Query: 3541 VLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKG 3720
VLLLDEATSALD+ESEKIVQ+ALD A +GRT +VIAHRLSTIQN+D I ++ GKIVE+G
Sbjct: 1219 VLLLDEATSALDSESEKIVQDALDKASKGRTTIVIAHRLSTIQNADKIYVIMRGKIVEQG 1278
Query: 3721 THDELIRKSEIY 3756
H ELI Y
Sbjct: 1279 KHQELIDLKGFY 1290
Score = 391 bits (1005), Expect = e-107
Identities = 209/548 (38%), Positives = 336/548 (61%), Gaps = 26/548 (4%)
Frame = +1
Query: 310 DEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD 489
DE + +++ C+ + +G++ + + + F + E+++ ++R+ + +I+ Q + WFD
Sbjct: 754 DEQANSILRSCMIIICIGIITMISFFCYVGLFMAAGEKMIGRIRRRFYYSIMHQNVSWFD 813
Query: 490 KQQT--GNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFA 663
+++ G +T +LT D ++ ++ ++++ + G+G+G ++SW ++L ++
Sbjct: 814 RRENMVGAVTTKLTSDPTSLQGISAERVGDIIEIMSTVGFGFGIGLYFSWKLSLCILAVF 873
Query: 664 PLI----VLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFY 831
P+I ++G SK+ A + Y G E +++T SL ++
Sbjct: 874 PIISFFMFINGQLNSKNAAPA----KAAYEQCGVTLVEVVEAMKTAQSLGKEDYFSQKYN 929
Query: 832 NALEVGRQTGIVKYC-YMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDR-------- 984
N L++ ++ GI+K+ + I +NL +S A ++ G + + +
Sbjct: 930 NDLQIPKR-GIIKWGPLLSITNAITNLLTFSINAYGYYLGICFMKKTINYQQDVPNFVDE 988
Query: 985 -----GLIFTVFFAVLSGSTS---LGGALPHLASFGTARGAASTVLRVINSHPKIDPYSL 1140
G I + S +TS +G LP + G A GAA ++ +I+ P ID YS
Sbjct: 989 IIDTFGDIQKALMTINSATTSFAQIGNVLPDV---GKAVGAAKSIYNIIDRKPSIDCYSE 1045
Query: 1141 EGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLL 1320
EG +++KG+I FK++HFRYP+R D VLKGIS + + G IALVG+SGCGKST + L+
Sbjct: 1046 EGETFNDVKGEIEFKNIHFRYPTRADNEVLKGISFKAEQGKTIALVGASGCGKSTTIQLI 1105
Query: 1321 QRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMG---NEHATH 1491
+RFYDPT G VL+DG +++++N+H LR QIG+V QEPVLF ++ +NIK G ++
Sbjct: 1106 ERFYDPTSGEVLLDGHNIKDLNIHFLRNQIGLVGQEPVLFAESVIDNIKRGVPEGVEVSN 1165
Query: 1492 DQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEA 1671
+Q+ A KMANA+DFI +P+GY T VG++G QLSGGQKQRIAIARAL++NPK+LLLDEA
Sbjct: 1166 EQIYAAAKMANAHDFISAMPEGYNTMVGDRGSQLSGGQKQRIAIARALIRNPKVLLLDEA 1225
Query: 1672 TSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMS 1851
TSALD+E+E+ VQ ALD+A GRTTI++AHRLSTI+N D+I+V G IVE G H+EL+
Sbjct: 1226 TSALDSESEKIVQDALDKASKGRTTIVIAHRLSTIQNADKIYVIMRGKIVEQGKHQELID 1285
Query: 1852 KQGIFYDM 1875
+G +Y +
Sbjct: 1286 LKGFYYTL 1293
Score = 307 bits (787), Expect = 1e-81
Identities = 203/520 (39%), Positives = 285/520 (54%), Gaps = 12/520 (2%)
Frame = +1
Query: 2266 VGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVR- 2442
V F C E +K+R FK LLRQD ++D H TG+L ++ D ++
Sbjct: 126 VAGFLQTICFFVLSEYQGIKIRSLYFKALLRQDPGWFDC--HKTGELTSKIINDIQKIQD 183
Query: 2443 ---YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGK-Q 2610
F RL +S +T G L IGF W M + M G
Sbjct: 184 GMSLKFGRLFQTFSSFIT--GYL-IGFIKCWDLTLVVLCMFPFI-MVSMMGLGMSAGIFT 239
Query: 2611 IRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFA 2790
++ + EA +A Q + +IRTVHSL ++ F +Y + E N+K + G
Sbjct: 240 MKSHKPFSEACSIAEQTIGNIRTVHSLTQERSFCESYNTKIMETDKYNIKKSIGIGTGLG 299
Query: 2791 FSQSLIFFMYAAAFYLGSIFVNQQA----MQPIDVYRVFFAISFCGQMIGNTTSFIPDVV 2958
I A + G+ V + ++ V VF ++ Q + ++ I +
Sbjct: 300 CMMFFIMSSNALGSWYGNFVVRGKGGSDNVKAGTVLTVFMSVLLATQSLSQISTPINILN 359
Query: 2959 KARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTKVLQGFTLD 3135
A++AA ++ I+ ID S G GNI +V F YPTR VL+G L+
Sbjct: 360 SAKVAAFNVYQTIDRIPDIDCQSIGGECPTECNGNIRFEDVQFVYPTRLSHHVLKGLDLE 419
Query: 3136 IKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQE 3315
IK G+T+ALVG SGCGKST + L++R Y+ + G + +DG +IR LNI LR Q+ +V QE
Sbjct: 420 IKKGQTIALVGASGCGKSTTIQLIQRNYDPNGGRVTLDGKDIRELNIKWLRNQIGLVGQE 479
Query: 3316 PTLFDCTIGENICYGTNRNVT--YQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSG 3489
P LF TI ENI G T +E++E AKMAN H+FI LP+GYDT +GEKG LSG
Sbjct: 480 PVLFAGTIRENIMLGAKEGATPSEEEMIECAKMANAHDFISKLPEGYDTIIGEKGALLSG 539
Query: 3490 GQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQ 3669
GQKQRIAIARAL+R+PS+LLLDEATSALDT+SEKIVQEAL+ A +GRT +++AHRL+T++
Sbjct: 540 GQKQRIAIARALIRNPSILLLDEATSALDTQSEKIVQEALEKASKGRTTIIVAHRLTTVR 599
Query: 3670 NSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRIVE 3789
N+D I + +G+I+E+G H EL+ Y + Q + E
Sbjct: 600 NADKICVFHQGEIIEQGKHQELMDLKGTYYGLVKRQSMEE 639
>gi|422286|pir||S30328 multidrug resistance protein 2 - Entamoeba
histolytica
gi|158973|gb|AAA29113.1| P-glycoprotein-2
Length = 1310
Score = 761 bits (1966), Expect = 0.0
Identities = 464/1268 (36%), Positives = 699/1268 (54%), Gaps = 53/1268 (4%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDN----V 279
++ Y +DL+LL G +V G P +V+G M F +D + N
Sbjct: 42 LYRYANWLDLILLAVGIFGSVGCGVLTPCQMLVMGDMVDTF---NTNDLMKAFPNQEAMY 98
Query: 280 NPEGLVPIS-------LDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKL 438
+P+ +P + D N V+K + + GV F ++ CF +ER +
Sbjct: 99 DPKYYIPFNHEVTKTVADTINDLVLKMVCFAIGSGVGSFLMTF----CFFVMSERQGINI 154
Query: 439 RQNYLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVG 618
R Y +A+LRQ W+D ++G LT+R+ D++++++G+ KF ++ Q +F+AGY +G
Sbjct: 155 RMLYFRALLRQDAGWYDFHESGELTSRIASDVQQIQDGMSQKFGIIFQTTTSFIAGYAIG 214
Query: 619 FFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSL 798
F W +TLV+M +P IVLS ++ T + +E+ AGAIAE T ++RTVHSL
Sbjct: 215 FAKDWDLTLVIMSMSPFIVLSMTLLAVFATKFTVLGEESLGNAGAIAEATIGNMRTVHSL 274
Query: 799 NGHKRELDRFYNA-LEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIIND-- 969
G + E YN + V + ++K +G+G+G + +++L WY S ++
Sbjct: 275 -GQEHEFCEMYNEKIRVVDRYNVLKGLTVGLGLGAVMFFIMGAFSLGSWYASVVLRGKGG 333
Query: 970 -PTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEG 1146
G + VF VL + L L F TA+ +A + + I+ P ID S G
Sbjct: 334 KKNVTAGDVMIVFICVLIATQGLSIIAIPLNIFATAKASAYRIYQTIDRIPDIDCRSTAG 393
Query: 1147 ILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQR 1326
G+I+ +DV FRYP+R +L G+ LE+K G +ALVG+SGCGKST + L+QR
Sbjct: 394 ECPTECNGNITLEDVQFRYPTRPTKQILGGLDLEIKKGQTVALVGASGCGKSTTIQLVQR 453
Query: 1327 FYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMG---NEHATHDQ 1497
YDP G V +DG DLR++N+ LR QIG+V QEP+LF TI ENI +G E T ++
Sbjct: 454 NYDPVGGSVKLDGKDLRDLNIKWLRNQIGLVGQEPILFACTIRENIMLGARDGETPTEEE 513
Query: 1498 VVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATS 1677
++E KMANA++FI LP+GY T VGEKG LSGGQKQRIAIARAL++ P ILLLDEATS
Sbjct: 514 MIECAKMANAHEFISHLPEGYDTMVGEKGAALSGGQKQRIAIARALIRKPTILLLDEATS 573
Query: 1678 ALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQ 1857
ALDT++E+ VQ AL++A GRTTI+VAHRL+T+RN RI VF G I+E G+H+ELM +
Sbjct: 574 ALDTQSEKIVQQALEKASQGRTTIVVAHRLTTVRNASRICVFHQGEIIEQGTHQELMDLK 633
Query: 1858 GIFYDMTXXXXXXXXXXEAGKDIEDTI-----SESAHSHLXXXXXXXXXXXXXXXIHQLA 2022
G +Y + + + +E+ + E+ + + +L
Sbjct: 634 GTYYGLVKRQSMEEEVDQ--ETVENDLKKIREQENKEAEEINQHKNTDTNEDPDIVQKLE 691
Query: 2023 EEV--EECKAPPTSMFKIFK--FNGDKVGW--XXXXXXXXXXXXSVTPVFALVYAEI--- 2175
E E K ++ F + + + + W ++ P F L ++
Sbjct: 692 NEYNSEMKKLKHSNRFVLLRVILDNFRHEWFLSTFGFIGGIGGGAIFPFFTLKIVDLIMC 751
Query: 2176 ---FNVYSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFK 2346
N +L DQ + + C + V++G+ F+ FF G + ++R + +
Sbjct: 752 LLSINSDTLTDDQ-KDTIKNICIIVVVIGVASFLSFFMYIGLFLSAGFKMIGRVRKDMYH 810
Query: 2347 NLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVF-TRLPVVLASIVTICGALGIGFYYG 2523
+++ Q+I+++D + G L TR A+D ++ + R+ V+ I TI ALGI FYY
Sbjct: 811 SIMHQNISWFDRKENMVGSLTTRLASDPTTLQGISGERVGNVIHIISTIGFALGIAFYYD 870
Query: 2524 WQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQE 2703
W+ + + ++ + E++G +AVE +RTV SL R+E
Sbjct: 871 WKVSLAVMAVSPVLIVVVFINGKLNSLEACPAQAAYEKSGITLVEAVESVRTVQSLTREE 930
Query: 2704 QFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPI-- 2877
F+ + + LREP K A + L M FY+G+ + +++ +
Sbjct: 931 HFYEVFKDALREPKIGIYKWAPLLSIFMCLTTLLTQVMNPYGFYIGTYLIKKKSNYDLPV 990
Query: 2878 ------------DVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDS 3021
++ + A+ F Q +GN + +PD+ KA AA + +I+ ID
Sbjct: 991 PDFMIEFSDRFEEMQKAIMAVIFAAQAVGNLGNIVPDIGKAVRAAKNTYDVIDRKPTIDC 1050
Query: 3022 LSDSG-IVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIM 3198
S+ G + G I +++ F YPTR D VL+G + ++ GKTVALVG SGCGKST +
Sbjct: 1051 YSEEGETFNDVKGEIEFKDICFRYPTRPDNSVLKGISFKVEQGKTVALVGASGCGKSTSV 1110
Query: 3199 GLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNR--N 3372
L+ERFY+ G +++DG NI++LNI LR Q+ +V QEP LF ++ +NI G +
Sbjct: 1111 QLIERFYDPTHGDVLLDGHNIKDLNIHFLRSQIGMVGQEPVLFAESVMDNIRRGVPKGVE 1170
Query: 3373 VTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLL 3552
V+ ++I AAKMAN H+FI +P+GY+T VG++G Q+SGGQKQRIAIARAL+R+P VLLL
Sbjct: 1171 VSNEQIYAAAKMANAHDFISAMPEGYNTMVGDRGAQISGGQKQRIAIARALIRNPKVLLL 1230
Query: 3553 DEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDE 3732
DEATSALD+ESEKIVQ+ALD A +GRT +VIAHRLSTIQN+D I ++ G+I E+GTH E
Sbjct: 1231 DEATSALDSESEKIVQDALDKAAKGRTTIVIAHRLSTIQNADQICVIMRGRIAERGTHQE 1290
Query: 3733 LIRKSEIY 3756
L+ Y
Sbjct: 1291 LLDLKGFY 1298
Score = 384 bits (987), Expect = e-105
Identities = 220/586 (37%), Positives = 341/586 (57%), Gaps = 24/586 (4%)
Frame = +1
Query: 190 FPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVL 369
F + + GG F + D ++ + ++N + L D+ + CI +V+GV
Sbjct: 726 FGFIGGIGGGAIFPFFTLKIVDLIMCLLSINSDTLT----DDQKDTIKNICIIVVVIGVA 781
Query: 370 MFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQT--GNLTARLTDDLERV 543
F + ++ I F S +++ ++R++ +I+ Q I WFD+++ G+LT RL D +
Sbjct: 782 SFLSFFMYIGLFLSAGFKMIGRVRKDMYHSIMHQNISWFDRKENMVGSLTTRLASDPTTL 841
Query: 544 REGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRV 723
+ G++ ++ + + G+ F+Y W ++L +M +P++++ K +
Sbjct: 842 QGISGERVGNVIHIISTIGFALGIAFYYDWKVSLAVMAVSPVLIVVVFINGKLNSLEACP 901
Query: 724 EQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYC-YMGIGVGF 900
Q Y +G E S+RTV SL + + F +AL + GI K+ + I +
Sbjct: 902 AQAAYEKSGITLVEAVESVRTVQSLTREEHFYEVFKDALREPK-IGIYKWAPLLSIFMCL 960
Query: 901 SNLCMYSSYALAFWYGSTLIINDPTFD------------------RGLIFTVFFAVLSGS 1026
+ L F+ G+ LI +D + ++ +F A G+
Sbjct: 961 TTLLTQVMNPYGFYIGTYLIKKKSNYDLPVPDFMIEFSDRFEEMQKAIMAVIFAAQAVGN 1020
Query: 1027 TSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYP 1206
LG +P + G A AA VI+ P ID YS EG +++KG+I FKD+ FRYP
Sbjct: 1021 --LGNIVPDI---GKAVRAAKNTYDVIDRKPTIDCYSEEGETFNDVKGEIEFKDICFRYP 1075
Query: 1207 SRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVN 1386
+R D VLKGIS +++ G +ALVG+SGCGKST V L++RFYDPT G VL+DG +++++N
Sbjct: 1076 TRPDNSVLKGISFKVEQGKTVALVGASGCGKSTSVQLIERFYDPTHGDVLLDGHNIKDLN 1135
Query: 1387 VHSLREQIGIVSQEPVLFDGTIYENIKMG---NEHATHDQVVEACKMANANDFIKRLPDG 1557
+H LR QIG+V QEPVLF ++ +NI+ G +++Q+ A KMANA+DFI +P+G
Sbjct: 1136 IHFLRSQIGMVGQEPVLFAESVMDNIRRGVPKGVEVSNEQIYAAAKMANAHDFISAMPEG 1195
Query: 1558 YGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAG 1737
Y T VG++G Q+SGGQKQRIAIARAL++NPK+LLLDEATSALD+E+E+ VQ ALD+A G
Sbjct: 1196 YNTMVGDRGAQISGGQKQRIAIARALIRNPKVLLLDEATSALDSESEKIVQDALDKAAKG 1255
Query: 1738 RTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM 1875
RTTI++AHRLSTI+N D+I V G I E G+H+EL+ +G +Y +
Sbjct: 1256 RTTIVIAHRLSTIQNADQICVIMRGRIAERGTHQELLDLKGFYYTL 1301
Score = 317 bits (812), Expect = 1e-84
Identities = 196/520 (37%), Positives = 281/520 (53%), Gaps = 12/520 (2%)
Frame = +1
Query: 2266 VGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRY 2445
VG F C E + +R F+ LLRQD +YD H +G+L +R A+D ++
Sbjct: 134 VGSFLMTFCFFVMSERQGINIRMLYFRALLRQDAGWYDF--HESGELTSRIASDVQQIQD 191
Query: 2446 VFT-RLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDT 2622
+ + ++ + + IGF W + +
Sbjct: 192 GMSQKFGIIFQTTTSFIAGYAIGFAKDWDLTLVIMSMSPFIVLSMTLLAVFATKFTVLGE 251
Query: 2623 QLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQS 2802
+ L AG +A + ++RTVHSL ++ +F Y E +R N+ T G
Sbjct: 252 ESLGNAGAIAEATIGNMRTVHSLGQEHEFCEMYNEKIRVVDRYNVLKGLTVG----LGLG 307
Query: 2803 LIFFMYAAAFYLGSIFVN--------QQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVV 2958
+ F AF LGS + + ++ + DV VF + Q + +
Sbjct: 308 AVMFFIMGAFSLGSWYASVVLRGKGGKKNVTAGDVMIVFICVLIATQGLSIIAIPLNIFA 367
Query: 2959 KARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTKVLQGFTLD 3135
A+ +A ++ I+ ID S +G GNI++ +V F YPTR ++L G L+
Sbjct: 368 TAKASAYRIYQTIDRIPDIDCRSTAGECPTECNGNITLEDVQFRYPTRPTKQILGGLDLE 427
Query: 3136 IKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQE 3315
IK G+TVALVG SGCGKST + L++R Y+ G + +DG ++R+LNI LR Q+ +V QE
Sbjct: 428 IKKGQTVALVGASGCGKSTTIQLVQRNYDPVGGSVKLDGKDLRDLNIKWLRNQIGLVGQE 487
Query: 3316 PTLFDCTIGENICYGTN--RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSG 3489
P LF CTI ENI G T +E++E AKMAN H FI LP+GYDT VGEKG LSG
Sbjct: 488 PILFACTIRENIMLGARDGETPTEEEMIECAKMANAHEFISHLPEGYDTMVGEKGAALSG 547
Query: 3490 GQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQ 3669
GQKQRIAIARAL+R P++LLLDEATSALDT+SEKIVQ+AL+ A QGRT +V+AHRL+T++
Sbjct: 548 GQKQRIAIARALIRKPTILLLDEATSALDTQSEKIVQQALEKASQGRTTIVVAHRLTTVR 607
Query: 3670 NSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRIVE 3789
N+ I + +G+I+E+GTH EL+ Y + Q + E
Sbjct: 608 NASRICVFHQGEIIEQGTHQELMDLKGTYYGLVKRQSMEE 647
>gi|27368849|emb|CAD59582.1| MDR-like ABC transporter [Oryza sativa
(japonica cultivar-group)]
gi|38344910|emb|CAD41854.2| OSJNBb0079B02.13 [Oryza sativa (japonica
cultivar-group)]
gi|38347317|emb|CAE05967.2| OSJNBa0063C18.8 [Oryza sativa (japonica
cultivar-group)]
Length = 1268
Score = 761 bits (1965), Expect = 0.0
Identities = 449/1246 (36%), Positives = 684/1246 (54%), Gaps = 24/1246 (1%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F + DL+L+ G++ A+ HGA PL ++ G D +N G
Sbjct: 44 LFTFADKWDLVLMAAGSLGALAHGAAMPLFFLLFG------------------DLINGFG 85
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
L EV KY +Y++ LG+++ +SY +IAC+ ER V LR+ YL A+LRQ
Sbjct: 86 KNQTDLRTMTDEVSKYALYFVYLGLVVCASSYAEIACWMYTGERQVIALRKAYLDAVLRQ 145
Query: 472 QIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLV 648
+ +FD +TG++ ++ D V++ +G+K + A FLAG VGF +W + L+
Sbjct: 146 DVGFFDTDARTGDIVFGVSTDTLLVQDAIGEKVGNFIHYIATFLAGLVVGFVAAWRLALL 205
Query: 649 MMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRF 828
+ P I +G + ++ T +E+YA AG +AE+ + +RTV+S G + L+ +
Sbjct: 206 SVAVIPAIAFAGGLYAYTLTGLTSKSRESYANAGVVAEQAIAQVRTVYSFAGESKALNSY 265
Query: 829 ----YNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIF 996
N L++G + G+ K +GIG + CM S+AL FWY I N T D G F
Sbjct: 266 SEAIQNTLKLGYKAGMAKG--LGIGCTYGIACM--SWALVFWYAGVFIRNGQT-DGGKAF 320
Query: 997 TVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDI 1176
T F+ + G SLG A +L +F + A +L VI P I +G L+ + G+I
Sbjct: 321 TAIFSAIVGGMSLGQAFSNLGAFSKGKIAGYKLLEVIRQKPSIVHDHKDGKLLAEVHGNI 380
Query: 1177 SFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVL 1356
FKDV F YPSR D+ + + SL A +A+VG SG GKST+V L++RFYDP +G+VL
Sbjct: 381 EFKDVTFSYPSRPDVMIFRDFSLFFPAAKTVAVVGGSGSGKSTVVALIERFYDPNEGQVL 440
Query: 1357 IDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDF 1536
+D VD++ + + LR+QIG+V+QEP LF TI+ENI G AT +V A +NA+ F
Sbjct: 441 LDNVDIKTLQLRWLRDQIGLVNQEPALFATTIHENILYGKPDATMAEVEAAATASNAHSF 500
Query: 1537 IKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGA 1716
I LP+GY T VGE+G+QLSGGQKQRIAIARA++KNPKILLLDEATSALD +E VQ A
Sbjct: 501 ISTLPNGYNTMVGERGIQLSGGQKQRIAIARAMLKNPKILLLDEATSALDAGSENIVQEA 560
Query: 1717 LDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSK--QGIFYDMTXXXX 1890
LD+ GRTT++VAHRLSTIRNV+ I V + G +VE+G+H+EL++K G + +
Sbjct: 561 LDRLMTGRTTVVVAHRLSTIRNVNMIAVIQQGQVVETGTHDELLAKGSSGAYASLIRFQE 620
Query: 1891 XXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQL-------------AEEV 2031
G + S S L +Q A+
Sbjct: 621 MAQNRDLGGASTRRSRSMHLTSSLSTKSLSLRSGSLRNLSYQYSTGANGRIEMISNADND 680
Query: 2032 EECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNV-YSLPADQM 2208
+ AP FK+ K N + + + P FA+V E+ +V Y ++M
Sbjct: 681 RKYPAPRGYFFKLLKLNAPEWPYAVLGAVGSVLSGFIGPTFAIVMGEMLDVFYYRDPNEM 740
Query: 2209 QANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLR 2388
+ + +++ G+ V + GE+LT ++R +L ++ ++D+
Sbjct: 741 EKKTKLYVFIYIGTGLYAVVAYLVQHYFFSIMGENLTTRVRRMMLSAILTNEVGWFDEEE 800
Query: 2389 HGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXX 2565
+ + + R A DA +V+ + R+ V+L ++ ++ + +GF W+
Sbjct: 801 NNSSLVAARLAVDAADVKSAIAERISVILQNMTSLMTSFIVGFIIEWRVALLILATFPLL 860
Query: 2566 XMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPF 2745
+ + + G + ++ VA + V +IRTV + N Q + + LR P
Sbjct: 861 VLANFAQQLSMKGFAGDTAKAHAKSSMVAGEGVSNIRTVAAFNAQNKILSLFSYELRIPE 920
Query: 2746 NTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMI 2925
L+ + T G +F SQ ++ A + GS V V +VF + +
Sbjct: 921 QQILRRSQTSGLLFGLSQLCLYSSEALILWYGSHLVRSHGSTFSKVIKVFVVLVVTANSV 980
Query: 2926 GNTTSFIPDVVKARLAASLLFYLIEHPTPID-SLSDSGIVKPITGNISIRNVFFNYPTRK 3102
T S P++V+ + +F ++ T I+ +S V + G+I +R+V F YP R
Sbjct: 981 AETVSLAPEIVRGGESIRSIFGILNRATRIEPDDPESERVTNVRGDIELRHVDFAYPARP 1040
Query: 3103 DTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISS 3282
D ++ + F L I+AG++ ALVG SG GKST++ L+ERFY+ G + IDG +IR LN+ +
Sbjct: 1041 DIQIFKDFNLKIQAGRSQALVGASGSGKSTVIALIERFYDPTGGKVTIDGKDIRRLNLKA 1100
Query: 3283 LREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHV 3462
LR ++ +V QEP LF +I ENI YG + T +E+++AAK AN+H F+ LP+GY T V
Sbjct: 1101 LRLKIGLVQQEPVLFAASILENIAYGKD-GATEEEVIQAAKTANVHGFVSQLPNGYKTAV 1159
Query: 3463 GEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLV 3642
GE+G QLSGGQKQRIAIARA+++ P++LLLDEATSALD ESE ++QEAL+ +GRT ++
Sbjct: 1160 GERGVQLSGGQKQRIAIARAVLKDPAILLLDEATSALDAESECVLQEALERLMKGRTTVL 1219
Query: 3643 IAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSE-IYQKFCETQ 3777
+AHRLSTI+ D IA+V +G+IVE G+H +L+ + E Y + + Q
Sbjct: 1220 VAHRLSTIRGVDRIAVVQDGRIVEHGSHSDLVSRPEGAYSRLLQLQ 1265
>gi|27368847|emb|CAD59581.1| MDR-like ABC transporter [Oryza sativa
(japonica cultivar-group)]
Length = 1256
Score = 758 bits (1957), Expect = 0.0
Identities = 449/1246 (36%), Positives = 689/1246 (55%), Gaps = 24/1246 (1%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F + +D LL+ G+ AV+HGA P+ ++ G + F + Q+S
Sbjct: 34 LFGFADPLDWLLMAAGSAGAVVHGAAMPVFFLLFGELINGFGKNQHS------------- 80
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
L E Y +Y++ LG+++ +SY++IAC+ ER V LR+ YL+A+LRQ
Sbjct: 81 -----LRRMTDE---YSLYFVYLGLVVCASSYLEIACWMYTGERQVGALRRRYLEAVLRQ 132
Query: 472 QIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLV 648
+ +FD +TG++ ++ D V++ +G+K + + FLAG VGF +W + L+
Sbjct: 133 DVGFFDTDARTGDVVFSVSTDTLLVQDAIGEKVGNFIHYLSTFLAGLVVGFVSAWRLALL 192
Query: 649 MMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRF 828
+ P I +G + ++ T +++YA AG IAE+ + +RTV+S G + L+ +
Sbjct: 193 SIAVIPGIAFAGGLYAYTLTGLTSKSRDSYANAGIIAEQAIAQVRTVYSYVGESKALNSY 252
Query: 829 ----YNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIF 996
N L++G + G+ K +GIG + CM S+AL FWY I N T D G F
Sbjct: 253 SEAIQNTLKLGYKAGMAKG--LGIGCTYGIACM--SWALVFWYAGVFIRNGQT-DGGKAF 307
Query: 997 TVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDI 1176
T F+ + G SLG + +L +F + A +L VI P I +G +D + G+I
Sbjct: 308 TAIFSAIVGGLSLGQSFSNLGAFSKGKIAGYKLLEVIRQRPTIVQDPADGRCLDEVHGNI 367
Query: 1177 SFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVL 1356
FK+V F YPSR D+ + + SL AG A+VG SG GKST+V L++RFYDP +G+VL
Sbjct: 368 EFKEVAFSYPSRPDVMIFRDFSLFFPAGKTAAVVGGSGSGKSTVVALIERFYDPNQGQVL 427
Query: 1357 IDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDF 1536
+D VD++ + + LR+QIG+V+QEP LF TI ENI G AT +V A ANA+ F
Sbjct: 428 LDNVDIKTLQLKWLRDQIGLVNQEPALFATTILENILYGKPDATMAEVEAAATSANAHSF 487
Query: 1537 IKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGA 1716
I LP+GY T+VGE+G+QLSGGQKQRIAIARA++KNPKILLLDEATSALD +E VQ A
Sbjct: 488 IALLPNGYNTQVGERGLQLSGGQKQRIAIARAMLKNPKILLLDEATSALDAGSENIVQEA 547
Query: 1717 LDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSK--QGIFYDMTXXXX 1890
LD+ GRTT++VAHRLSTIR VD I V + G +VE+G+H+EL++K G + +
Sbjct: 548 LDRLMVGRTTVVVAHRLSTIRCVDMIAVIQQGQVVETGTHDELLAKGSSGAYAALIRFQE 607
Query: 1891 XXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQL-------------AEEV 2031
G + S + L + A+
Sbjct: 608 MARNRDFRGPSTRKSRSSRLSNSLSTRSLSLRSGSLRNLSYSYSTGADGRIEMVSNADND 667
Query: 2032 EECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNV-YSLPADQM 2208
+ AP FK+ K N + + + P FA+V + + V Y + M
Sbjct: 668 RKYPAPKGYFFKLLKLNAPEWPYTILGAIGSILSGFIGPTFAIVMSNMIEVFYFRDPNAM 727
Query: 2209 QANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLR 2388
+ + +++ G+ V + GE+LT ++R +LR D+ ++D
Sbjct: 728 ERKTREYVFIYIGTGLYAVVAYLVQHYFFSIMGENLTTRVRRMMLAAILRNDVGWFDQEE 787
Query: 2389 HGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXX 2565
+ + + R +TDA +V+ + R+ V+L ++ ++ + +GF W+
Sbjct: 788 NNSSLVAARLSTDAADVKSAIAERISVILQNMTSLLVSFVVGFIIEWRVAVLILVTFPLL 847
Query: 2566 XMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPF 2745
+ + + G + + +A + V +IRTV + N Q++ +C LR P
Sbjct: 848 VLANFAQQLSMKGFAGDTAKAHAKTSMIAGEGVSNIRTVAAFNAQDKVLSLFCTELRVPQ 907
Query: 2746 NTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMI 2925
+L+ + GA+F SQ ++ A + G+ V V +VF + +
Sbjct: 908 MHSLRRSQISGALFGLSQLSLYASEALILWYGAHLVRHHVSTFSKVIKVFVVLVITANTV 967
Query: 2926 GNTTSFIPDVVKARLAASLLFYLIEHPTPID-SLSDSGIVKPITGNISIRNVFFNYPTRK 3102
T S P++V+ + +F ++ + T ID ++ V+ + G+I R+V F YP+R
Sbjct: 968 AETVSLAPEIVRGGESIRSVFAILNYRTRIDPDEPETEPVESVRGDIDFRHVDFAYPSRP 1027
Query: 3103 DTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISS 3282
D V + F+L I+AG++ ALVG SG GKST++ L+ERFY+ G +MIDG +IR LN+ S
Sbjct: 1028 DVMVFKDFSLRIRAGQSQALVGASGSGKSTVIALIERFYDPLAGKVMIDGKDIRRLNVRS 1087
Query: 3283 LREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHV 3462
LR ++ +V QEP LF +I ENI YG + T +E++EAAK+AN+H F+ LP+GY T V
Sbjct: 1088 LRLKIGLVQQEPVLFATSIFENIAYGKD-GATEEEVIEAAKVANMHGFVSALPEGYKTPV 1146
Query: 3463 GEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLV 3642
GE+G QLSGGQKQRIAIARA+++ P+VLLLDEATSALD ESE ++QEAL+ +GRT ++
Sbjct: 1147 GERGVQLSGGQKQRIAIARAVLKDPAVLLLDEATSALDAESECVLQEALERIMKGRTAVL 1206
Query: 3643 IAHRLSTIQNSDVIAIVSEGKIVEKGTHDELI-RKSEIYQKFCETQ 3777
+AHRLSTI+ D IA+V +G++VE+G+H EL+ R Y + + Q
Sbjct: 1207 VAHRLSTIRGVDSIAVVQDGRVVEQGSHGELVSRPDGAYSRLLQLQ 1252
>gi|50543630|ref|XP_499981.1| hypothetical protein [Yarrowia
lipolytica]
gi|49645846|emb|CAG83910.1| unnamed protein product [Yarrowia
lipolytica CLIB99]
Length = 1254
Score = 757 bits (1955), Expect = 0.0
Identities = 464/1244 (37%), Positives = 673/1244 (53%), Gaps = 23/1244 (1%)
Frame = +1
Query: 121 YTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVP 300
Y +D ++ V + GA PL ++ G MT F+R FV EG P
Sbjct: 38 YATPLDKAEILVSYVFSACAGACLPLFTLIFGSMTNEFVRY----FV--------EGATP 85
Query: 301 ISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQ 480
EF ++ Y++ L +F S+++ E+L ++R +YL+AI+RQ I
Sbjct: 86 A---EFGHQINYLARYFIYLFAGIFAFSFLETYMHVQMGEKLTGRIRAHYLEAIMRQNIG 142
Query: 481 WFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMG- 657
+FDK G +T R+T D ++EG+ +K L+V AA ++ + +GF SW +TL+MM
Sbjct: 143 FFDKVGAGEITNRITTDTNLIQEGISEKAGLIVSSIAAIISAFIIGFIKSWKLTLIMMSS 202
Query: 658 -FAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYN 834
FA L ++ A + + + A A ++AEE +IR V + R ++ +
Sbjct: 203 FFALLFAMTTAVYFVVKFAKLAIVSD--AKASSVAEEVLGAIRNVVAFGTQDRLTQKYDD 260
Query: 835 ALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAV 1014
L V + I + + Y +YAL+FW GS L+ + + G I TV FAV
Sbjct: 261 RLVVSMKYHIFRGRGSAAAIASVWTIAYLNYALSFWEGSRLV-SWGQVNVGNIMTVLFAV 319
Query: 1015 LSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVH 1194
+ G+ +G P+L + G+A + + I+ P ID +S +G +D + G I + V+
Sbjct: 320 MIGAVMVGNVAPNLQAMGSAIASGQKIFETIDRVPPIDSFSDKGQKLDQVHGHIQLEHVN 379
Query: 1195 FRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDL 1374
FRYPSR D+ VL SLE+K G +ALVG+SG GKSTI+ +L+RFY+ G+V IDGVD+
Sbjct: 380 FRYPSRPDVSVLHDFSLEIKPGQTVALVGASGSGKSTIIGILERFYEILGGKVTIDGVDI 439
Query: 1375 REVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQ---------VVEACKMANA 1527
+NV LR+Q+ +VSQEP LF +IYENI G H+ V +A + ANA
Sbjct: 440 SSLNVRWLRQQLALVSQEPTLFGVSIYENIAYGLIGTPHENADPEKKRQLVEDAARQANA 499
Query: 1528 NDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREV 1707
DFI+ L DG+ T VG++G LSGGQKQRIAIARA+V+ PKILLLDEATSALDT++E V
Sbjct: 500 YDFIQDLTDGFETNVGDRGFLLSGGQKQRIAIARAIVREPKILLLDEATSALDTKSEGIV 559
Query: 1708 QGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXX 1887
Q ALD+A A RTTI++AHRLST++N D I V G+IVE G+H EL+ ++G+++ +
Sbjct: 560 QDALDKAAADRTTIVIAHRLSTVKNADLIVVMNKGSIVEQGTHHELIEQKGMYFSLV--- 616
Query: 1888 XXXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKAPPTSMFK 2067
+ D DT ++ + +E+ EE + +
Sbjct: 617 -NSQTIMKQNDDGSDTAADD-------KLEEDVVAIQSLTMSSFSEDEEEYNTKEQGIIE 668
Query: 2068 ----IFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPAD---QMQANVYF 2226
++ +N ++ P A+++A+ + P M++ +
Sbjct: 669 MIRFVYSYNKEETTLLLIGGACAFVGGIGYPGMAVIFAKCIEAFMTPPSGYPHMRSLINT 728
Query: 2227 WCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKL 2406
+ G+F ++ + V F+ + L GE L KLR FK LR DI F+D + TG L
Sbjct: 729 YTGLFFMIAMIEMVAFYVEISILTLAGERLVRKLRLAVFKQFLRMDIGFFDREENTTGSL 788
Query: 2407 CTRFATDAPNVRYVF-TRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYF 2583
+ DA NVR + T +L SIVT+ + + W+ G+
Sbjct: 789 TSNLGKDAHNVRGLSGTTFGQILVSIVTVVAGFVVSVVFNWRMGLICGACIPILIGCGFC 848
Query: 2584 EMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKH 2763
+ R E++G A + IRTV +L R+ Q + TY E + + +
Sbjct: 849 RYYVLTWLNNRAKLAYEQSGSYACENTNAIRTVTTLTREYQVYKTYKESVEGQVQGSKRP 908
Query: 2764 AHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSF 2943
+F SQSL + AF+ G I + + P + F AI F Q G+ +F
Sbjct: 909 IFFSSILFGLSQSLSPLIMGLAFWYGGILLKHHTISPFRFFVAFIAIVFGSQSAGSIFTF 968
Query: 2944 IPDVVKARLAASLLFYLIEHPTPIDSLSDSGI---VKPITGNISIRNVFFNYPTRKDTKV 3114
PD+ KA + + ++ ID SD G K + GNI +NV F YPTR V
Sbjct: 969 APDMSKAAGSTRNIMNVLAVEPEIDWWSDQGTKIDPKDVKGNIEFQNVHFRYPTRMQVPV 1028
Query: 3115 LQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQ 3294
L+G L IK G+ VALVG SGCGKST +GLLE FY G I++DG ++ +LNI+S RE
Sbjct: 1029 LRGLNLSIKQGQYVALVGSSGCGKSTTVGLLECFYRPTSGKILLDGLDLADLNINSYREA 1088
Query: 3295 VCIVSQEPTLFDCTIGENICYGT-NRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEK 3471
V +V QEP LF TI ENI GT + +VT + + EAA+ +NIH+FI+ LP+GYDT G K
Sbjct: 1089 VALVQQEPILFSGTIKENILLGTQDPDVTDEVVYEAARKSNIHDFIMSLPEGYDTVCGSK 1148
Query: 3472 GTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAH 3651
G+ LSGGQKQRIAIARAL+R+P +LLLDEATSALD+ESEK+VQ ALDAA +GRT + IAH
Sbjct: 1149 GSLLSGGQKQRIAIARALIRNPKILLLDEATSALDSESEKVVQAALDAAAKGRTTIAIAH 1208
Query: 3652 RLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRI 3783
RLSTIQN+DVI + G ++E GTH +L+ Y + + Q +
Sbjct: 1209 RLSTIQNADVIFVFENGVVLESGTHQQLLANRSKYYELVKLQAL 1252
Score = 384 bits (986), Expect = e-105
Identities = 224/594 (37%), Positives = 332/594 (55%), Gaps = 6/594 (1%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
++ Y + LLLI G A + G G+P +A++ F+
Sbjct: 673 VYSYNKEETTLLLIGGA-CAFVGGIGYPGMAVIFAKCIEAFMTP---------------- 715
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
P S + Y + ++ ++ YV+I+ ERLV KLR K LR
Sbjct: 716 --PSGYPHMRSLINTYTGLFFMIAMIEMVAFYVEISILTLAGERLVRKLRLAVFKQFLRM 773
Query: 472 QIQWFDKQQ--TGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTL 645
I +FD+++ TG+LT+ L D VR G F ++ +AG+ V ++W M L
Sbjct: 774 DIGFFDREENTTGSLTSNLGKDAHNVRGLSGTTFGQILVSIVTVVAGFVVSVVFNWRMGL 833
Query: 646 VMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDR 825
+ P+++ G + + Y +G+ A E ++IRTV +L +
Sbjct: 834 ICGACIPILIGCGFCRYYVLTWLNNRAKLAYEQSGSYACENTNAIRTVTTLTREYQVYKT 893
Query: 826 FYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVF 1005
+ ++E Q + I G S LAFWYG +++ T F F
Sbjct: 894 YKESVEGQVQGSKRPIFFSSILFGLSQSLSPLIMGLAFWYGG-ILLKHHTISPFRFFVAF 952
Query: 1006 FAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVD--NMKGDIS 1179
A++ GS S G A G+ ++ V+ P+ID +S +G +D ++KG+I
Sbjct: 953 IAIVFGSQSAGSIFTFAPDMSKAAGSTRNIMNVLAVEPEIDWWSDQGTKIDPKDVKGNIE 1012
Query: 1180 FKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLI 1359
F++VHFRYP+R + VL+G++L +K G +ALVGSSGCGKST V LL+ FY PT G++L+
Sbjct: 1013 FQNVHFRYPTRMQVPVLRGLNLSIKQGQYVALVGSSGCGKSTTVGLLECFYRPTSGKILL 1072
Query: 1360 DGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEH--ATHDQVVEACKMANAND 1533
DG+DL ++N++S RE + +V QEP+LF GTI ENI +G + T + V EA + +N +D
Sbjct: 1073 DGLDLADLNINSYREAVALVQQEPILFSGTIKENILLGTQDPDVTDEVVYEAARKSNIHD 1132
Query: 1534 FIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQG 1713
FI LP+GY T G KG LSGGQKQRIAIARAL++NPKILLLDEATSALD+E+E+ VQ
Sbjct: 1133 FIMSLPEGYDTVCGSKGSLLSGGQKQRIAIARALIRNPKILLLDEATSALDSESEKVVQA 1192
Query: 1714 ALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM 1875
ALD A GRTTI +AHRLSTI+N D IFVF+ G ++ESG+H++L++ + +Y++
Sbjct: 1193 ALDAAAKGRTTIAIAHRLSTIQNADVIFVFENGVVLESGTHQQLLANRSKYYEL 1246
Score = 324 bits (831), Expect = 9e-87
Identities = 204/569 (35%), Positives = 312/569 (53%), Gaps = 21/569 (3%)
Frame = +1
Query: 2146 PVFALVYAEIFNVY-------SLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRC 2304
P+F L++ + N + + PA+ + + F+ + F F +
Sbjct: 62 PLFTLIFGSMTNEFVRYFVEGATPAE-FGHQINYLARYFIYLFAGIFAFSFLETYMHVQM 120
Query: 2305 GESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASI 2481
GE LT ++R + ++RQ+I F+D + G G++ R TD ++ + + ++++SI
Sbjct: 121 GEKLTGRIRAHYLEAIMRQNIGFFDKV--GAGEITNRITTDTNLIQEGISEKAGLIVSSI 178
Query: 2482 VTICGALGIGFYYGWQXX----XXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKV 2649
I A IGF W+ YF ++ + D + A V
Sbjct: 179 AAIISAFIIGFIKSWKLTLIMMSSFFALLFAMTTAVYFVVKFAKLAIVSDAK----ASSV 234
Query: 2650 ASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAA 2829
A + + IR V + Q++ Y + L ++ A A ++ + YA +
Sbjct: 235 AEEVLGAIRNVVAFGTQDRLTQKYDDRLVVSMKYHIFRGRGSAAAIASVWTIAYLNYALS 294
Query: 2830 FYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPT 3009
F+ GS V+ + ++ V FA+ M+GN + + A + +F I+
Sbjct: 295 FWEGSRLVSWGQVNVGNIMTVLFAVMIGAVMVGNVAPNLQAMGSAIASGQKIFETIDRVP 354
Query: 3010 PIDSLSDSGI-VKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGK 3186
PIDS SD G + + G+I + +V F YP+R D VL F+L+IK G+TVALVG SG GK
Sbjct: 355 PIDSFSDKGQKLDQVHGHIQLEHVNFRYPSRPDVSVLHDFSLEIKPGQTVALVGASGSGK 414
Query: 3187 STIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYG-- 3360
STI+G+LERFY G + IDG +I +LN+ LR+Q+ +VSQEPTLF +I ENI YG
Sbjct: 415 STIIGILERFYEILGGKVTIDGVDISSLNVRWLRQQLALVSQEPTLFGVSIYENIAYGLI 474
Query: 3361 ------TNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARA 3522
+ Q + +AA+ AN ++FI L DG++T+VG++G LSGGQKQRIAIARA
Sbjct: 475 GTPHENADPEKKRQLVEDAARQANAYDFIQDLTDGFETNVGDRGFLLSGGQKQRIAIARA 534
Query: 3523 LVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEG 3702
+VR P +LLLDEATSALDT+SE IVQ+ALD A RT +VIAHRLST++N+D+I ++++G
Sbjct: 535 IVREPKILLLDEATSALDTKSEGIVQDALDKAAADRTTIVIAHRLSTVKNADLIVVMNKG 594
Query: 3703 KIVEKGTHDELIRKSEIYQKFCETQRIVE 3789
IVE+GTH ELI + +Y +Q I++
Sbjct: 595 SIVEQGTHHELIEQKGMYFSLVNSQTIMK 623
>gi|15217776|ref|NP_174115.1| multidrug resistance P-glycoprotein,
putative [Arabidopsis thaliana]
gi|25297458|pir||G86404 probable P-glycoprotein [imported] -
Arabidopsis thaliana
gi|12322992|gb|AAG51482.1| P-glycoprotein, putative [Arabidopsis
thaliana]
Length = 1245
Score = 756 bits (1952), Expect = 0.0
Identities = 447/1239 (36%), Positives = 688/1239 (55%), Gaps = 13/1239 (1%)
Frame = +1
Query: 109 GIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPE 288
G+F +D L++ G + A IHGA PL + G M +G + +P+
Sbjct: 34 GLFSAADKLDYFLMLLGGLGACIHGATLPLFFVFFGKMLDS----------LGNLSTDPK 83
Query: 289 GLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILR 468
+ +S V + +Y + LG++ F ++++ ++C+ ER +LR NYLK+IL
Sbjct: 84 AI--------SSRVSQNALYLVYLGLVNFVSAWIGVSCWMQTGERQTARLRINYLKSILA 135
Query: 469 QQIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTL 645
+ I +FD + + NL ++ D V++ +GDK +++ + F+AG+ +GF W +TL
Sbjct: 136 KDITFFDTEARDSNLIFHISSDAILVQDAIGDKTDHVLRYLSQFIAGFVIGFLSVWQLTL 195
Query: 646 VMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDR 825
+ +G PLI ++G + M+T + + YA AG +AEE S +RTV++ G ++ +
Sbjct: 196 LTLGVVPLIAIAGGGYAIVMSTISEKSETAYADAGKVAEEVMSQVRTVYAFVGEEKAVKS 255
Query: 826 FYN----ALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLI 993
+ N AL++G+++G+ K G+GVG + ++ ++AL WY S L+ + T +
Sbjct: 256 YSNSLKKALKLGKRSGLAK----GLGVGLTYSLLFCAWALLLWYASLLVRHGKT-NGAKA 310
Query: 994 FTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSL-EGILVDNMKG 1170
FT V+ +LG A P L++ R AA+ + R+I ++ L EG + N+ G
Sbjct: 311 FTTILNVIFSGFALGQAAPSLSAIAKGRVAAANIFRMIGNNNSESSQRLDEGTTLQNVAG 370
Query: 1171 DISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGR 1350
I F+ V F YPSR ++ V + +S +++G A VG SG GKSTI++++QRFY+P G
Sbjct: 371 RIEFQKVSFAYPSRPNM-VFENLSFTIRSGKTFAFVGPSGSGKSTIISMVQRFYEPNSGE 429
Query: 1351 VLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAN 1530
+L+DG D++ + + REQ+G+VSQEP LF TI NI +G E+A DQ++EA K ANA+
Sbjct: 430 ILLDGNDIKSLKLKWFREQLGLVSQEPALFATTIASNILLGKENANMDQIIEAAKAANAD 489
Query: 1531 DFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQ 1710
FIK LP+GY T+VGE G QLSGGQKQRIAIARA+++NPKILLLDEATSALD E+E+ VQ
Sbjct: 490 SFIKSLPNGYNTQVGEGGTQLSGGQKQRIAIARAVLRNPKILLLDEATSALDAESEKIVQ 549
Query: 1711 GALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXX 1890
ALD RTTI+VAHRLSTIRNVD+I V + G + E+GSH ELM + G + T
Sbjct: 550 QALDNVMEKRTTIVVAHRLSTIRNVDKIVVLRDGQVRETGSHSELMLRGGDY--ATLVNC 607
Query: 1891 XXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECK---APPTSM 2061
E + I +S + Q + ++ K + + +
Sbjct: 608 QETEPQENSRSIMSETCKSQAGSSSSRRVSSSRRTSSFRVDQEKTKNDDSKKDFSSSSMI 667
Query: 2062 FKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLP-ADQMQANVYFWCGM 2238
+++ K N + + + TP+F++ A + + P + ++ +V +
Sbjct: 668 WELIKLNSPEWPYALLGSIGAVLAGAQTPLFSMGIAYVLTAFYSPFPNVIKRDVEKVAII 727
Query: 2239 FVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRF 2418
F GI + GE LT ++R F +L +I ++D + TG L +
Sbjct: 728 FAGAGIVTAPIYLLQHYFYTLMGERLTSRVRLSLFSAILSNEIGWFDLDENNTGSLTSIL 787
Query: 2419 ATDAPNVRYVFT-RLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQM 2595
A DA VR RL ++ ++ AL + F+Y W+ E
Sbjct: 788 AADATLVRSALADRLSTIVQNLSLTVTALALAFFYSWRVAAVVTACFPLLIAASLTEQLF 847
Query: 2596 RFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTY 2775
G T+ A VA +A+ +IRTV + ++Q + L +P H
Sbjct: 848 LKGFGGDYTRAYSRATSVAREAIANIRTVAAYGAEKQISEQFTCELSKPTKNAFVRGHIS 907
Query: 2776 GAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDV 2955
G + SQ L F YA + S+ +N + D + F + + T + PD+
Sbjct: 908 GFGYGLSQFLAFCSYALGLWYVSVLINHKETNFGDSIKSFMVLIVTAFSVSETLALTPDI 967
Query: 2956 VKARLAASLLFYLIEHPTPID-SLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTL 3132
VK A +F ++ T I +S +V + G+I RNV F YPTR + + + L
Sbjct: 968 VKGTQALGSVFRVLHRETKISPDQPNSRMVSQVKGDIEFRNVSFVYPTRPEIDIFKNLNL 1027
Query: 3133 DIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQ 3312
+ AGK++A+VG SG GKST++GL+ RFY+ G + IDG +I+ LN+ SLR+++ +V Q
Sbjct: 1028 RVSAGKSLAVVGPSGSGKSTVIGLIMRFYDPSNGNLCIDGQDIKTLNLRSLRKKLALVQQ 1087
Query: 3313 EPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGG 3492
EP LF TI ENI YG N N + EI+EAAK AN H FI+ + +GY TH G+KG QLSGG
Sbjct: 1088 EPALFSTTIYENIKYG-NENASEAEIMEAAKAANAHEFIIKMEEGYKTHAGDKGVQLSGG 1146
Query: 3493 QKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQN 3672
QKQR+AIARA+++ PSVLLLDEATSALDT SEK+VQEALD +GRT +++AHRLSTI+
Sbjct: 1147 QKQRVAIARAVLKDPSVLLLDEATSALDTSSEKLVQEALDKLMKGRTTVLVAHRLSTIRK 1206
Query: 3673 SDVIAIVSEGKIVEKGTHDELIR-KSEIYQKFCETQRIV 3786
+D +A++ +G++VEKG+H EL+ + Y++ Q ++
Sbjct: 1207 ADTVAVLHKGRVVEKGSHRELVSIPNGFYKQLTSLQEVL 1245
>gi|39587987|emb|CAE57218.1| Hypothetical protein CBG00078
[Caenorhabditis briggsae]
Length = 1282
Score = 755 bits (1950), Expect = 0.0
Identities = 447/1189 (37%), Positives = 657/1189 (54%), Gaps = 45/1189 (3%)
Frame = +1
Query: 346 YYLVLGVLMFFTSYVQ--IACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTAR 519
+ L +G++ S + CF+ R++ ++R Y+ ++LRQ WFDK +G + +
Sbjct: 97 FLLFIGIICAIISGISQPYMCFQHCCSRIMAQMRHRYVYSVLRQNAGWFDKNHSGTIATK 156
Query: 520 LTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSK 699
L D +ER+REG+GDK +L++ A LA V + Y W + +M+G AP V + M++
Sbjct: 157 LNDSMERIREGIGDKLGVLIRGVAMLLASIVVAYIYEWRLACMMLGVAPTCVGCMSLMAR 216
Query: 700 SMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCY 879
M T E AG+IAEE+ +RTV + NG + ++R+ L GR+ I K +
Sbjct: 217 QMTATTVKELGGVEKAGSIAEESLMGVRTVQAFNGQEEMVERYRVELNKGRKFAIWKGFW 276
Query: 880 MGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLA 1059
G+ G +++ F YG+ L+ G +F + A+L GS LG PHL
Sbjct: 277 SGLYGGLFFFWLFAFQGCGFLYGAYLLKIGIITSPGDVFIIVMAMLLGSYFLGLISPHLM 336
Query: 1060 SFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGI 1239
AR AA+++ I PKIDPYS +G +D + G + F++VHFRYP+RKD +L G+
Sbjct: 337 VLLNARVAAASIYETIERVPKIDPYSKKGRFLDKVIGRVKFENVHFRYPTRKDAKILNGL 396
Query: 1240 SLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIV 1419
+L ++ G +ALVG SGCGKST V LL R Y+P G V IDG D+RE+N+ LR +GIV
Sbjct: 397 NLTIEPGTSVALVGHSGCGKSTSVGLLTRLYEPETGNVTIDGTDVRELNIDYLRNVVGIV 456
Query: 1420 SQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSG 1599
QEP+LF+ TI+ N+ +GN +A ++++E CKMANA+DFI+++P GY T +G+ GVQLSG
Sbjct: 457 QQEPILFNDTIHNNLLLGNPNAKREKMIEVCKMANAHDFIEKMPKGYDTLIGDGGVQLSG 516
Query: 1600 GQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIR 1779
GQKQR+AIAR L+++PK+LLLDEATSALD ++E VQ AL+ A GRTTI++AHRLSTIR
Sbjct: 517 GQKQRVAIARTLIRDPKVLLLDEATSALDAQSESVVQSALNNASKGRTTIMIAHRLSTIR 576
Query: 1780 NVDRIFVFKAGNIVES----------GSHEELMSKQGIF--------YDMTXXXXXXXXX 1905
D I F+ G IVE+ G + +L+ Q YD
Sbjct: 577 EADMIVFFEKGVIVEAGNHAELVRLEGRYYDLVKAQAFKPDDNPISQYDEIAEDIDLGPS 636
Query: 1906 XEAGKDIEDTISESAHSHLXXX-----------------XXXXXXXXXXXXIHQLAEEVE 2034
A + + + S S + ++A+ +E
Sbjct: 637 ATAIHSRQSSFTSSIRSRISGAEAFRRGTLGADSFAGGRSSARADAENAAFAEEVAKVME 696
Query: 2035 ECKAPPTSMFKIFK-FNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYS-LPAD-- 2202
+ IFK +G+ +T FAL++ +F + L D
Sbjct: 697 QDGQISAGFLDIFKNAHGNYTVMLLGFVTGLIRGLELT-AFALLFGWVFEGFQYLTVDNG 755
Query: 2203 QMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDD 2382
+M + + G FV F S+ E+L ++ R +F+NLL QD +F+D+
Sbjct: 756 KMMHRMAMAVIAYGCSGFGCFVSQFLSSVFFAIVSENLALRFRVMSFRNLLYQDASFFDN 815
Query: 2383 LRHGTGKLCTRFATDAPNVRYVF-TRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXX 2559
H GKL TR ATDAPN + V +R+ VL ++ I + I F Y W
Sbjct: 816 PAHAPGKLITRLATDAPNCKTVVDSRMLQVLYALSAIIANIAIAFIYCWYLAILGTALII 875
Query: 2560 XXXM---GGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEY 2730
+ G +++ + KQI+D +EAG++A + +E+++T+ L R + F Y +
Sbjct: 876 LLAVTMCGLAYKISLLNMKQIQD----DEAGRIAIEIIENVKTIQLLTRCDHFFERYQKS 931
Query: 2731 LREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISF 2910
+ + LK + +QS +++M F LG + Q DV++ A+
Sbjct: 932 SKSQKRSELKKGLIEAVNYTITQSFMYYMMCFCFALGIRLIYQGNKSSQDVFQGNIAMLL 991
Query: 2911 CGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNY 3090
+ N+ + P+ VKA+ A+ LLF +I L + G + GNI +V F+Y
Sbjct: 992 TAMGVMNSAQYFPEFVKAKTASGLLFNIIYRKPRTGDLME-GTCPEVRGNILFEDVKFSY 1050
Query: 3091 PTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNL 3270
P R +++G G+TVALVG SG GKST +G+LERFY+ G++ IDG +IR L
Sbjct: 1051 PQRPHQPIMKGLQWTALRGQTVALVGPSGSGKSTCIGMLERFYDVTGGVLRIDGQDIRGL 1110
Query: 3271 NISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGY 3450
++ LR Q+ +V QEP LF TI ENIC G NV+ ++I A ++AN + F+ LP G
Sbjct: 1111 SLFHLRTQMALVGQEPRLFAGTIKENICLGLE-NVSMEKINHALELANANRFLSNLPAGI 1169
Query: 3451 DTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGR 3630
+T VGEKG++LSGGQKQRIAIARALVR P +LLLDEATSALD+ESEK VQEALD A++GR
Sbjct: 1170 ETDVGEKGSKLSGGQKQRIAIARALVRDPKILLLDEATSALDSESEKAVQEALDRAREGR 1229
Query: 3631 TCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
TC+ IAHRLS+IQNSDVI + G++ E G H +L+ K Y + + Q
Sbjct: 1230 TCITIAHRLSSIQNSDVIVYIENGRVQEAGNHKQLMAKKGKYYELIQKQ 1278
Score = 288 bits (737), Expect = 7e-76
Identities = 180/517 (34%), Positives = 283/517 (53%), Gaps = 6/517 (1%)
Frame = +1
Query: 343 IYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDK--QQTGNLTA 516
I Y G F + ++ F +E L + R + +L Q +FD G L
Sbjct: 766 IAYGCSGFGCFVSQFLSSVFFAIVSENLALRFRVMSFRNLLYQDASFFDNPAHAPGKLIT 825
Query: 517 RLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLS----G 684
RL D + + + ++ +A +A + F Y W L ++G A +I+L+ G
Sbjct: 826 RLATDAPNCKTVVDSRMLQVLYALSAIIANIAIAFIYCWY--LAILGTALIILLAVTMCG 883
Query: 685 AKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGI 864
S+ +++ + AG IA E +++T+ L +R+ + + +++ +
Sbjct: 884 LAYKISLLNMKQIQDDE---AGRIAIEIIENVKTIQLLTRCDHFFERYQKSSKSQKRSEL 940
Query: 865 VKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGA 1044
K + + MY F G LI + +F A+L + + +
Sbjct: 941 KKGLIEAVNYTITQSFMYYMMCFCFALGIRLIYQGNKSSQD-VFQGNIAMLLTAMGVMNS 999
Query: 1045 LPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIH 1224
+ F A+ A+ + +I P+ +EG + ++G+I F+DV F YP R
Sbjct: 1000 AQYFPEFVKAKTASGLLFNIIYRKPRTGDL-MEGTCPE-VRGNILFEDVKFSYPQRPHQP 1057
Query: 1225 VLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLRE 1404
++KG+ G +ALVG SG GKST + +L+RFYD T G + IDG D+R +++ LR
Sbjct: 1058 IMKGLQWTALRGQTVALVGPSGSGKSTCIGMLERFYDVTGGVLRIDGQDIRGLSLFHLRT 1117
Query: 1405 QIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKG 1584
Q+ +V QEP LF GTI ENI +G E+ + +++ A ++ANAN F+ LP G T VGEKG
Sbjct: 1118 QMALVGQEPRLFAGTIKENICLGLENVSMEKINHALELANANRFLSNLPAGIETDVGEKG 1177
Query: 1585 VQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHR 1764
+LSGGQKQRIAIARALV++PKILLLDEATSALD+E+E+ VQ ALD+A+ GRT I +AHR
Sbjct: 1178 SKLSGGQKQRIAIARALVRDPKILLLDEATSALDSESEKAVQEALDRAREGRTCITIAHR 1237
Query: 1765 LSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM 1875
LS+I+N D I + G + E+G+H++LM+K+G +Y++
Sbjct: 1238 LSSIQNSDVIVYIENGRVQEAGNHKQLMAKKGKYYEL 1274
>gi|15147363|gb|AAG01549.3| multidrug resistance protein MDR
[Trichophyton rubrum]
Length = 1331
Score = 755 bits (1950), Expect = 0.0
Identities = 461/1271 (36%), Positives = 679/1271 (53%), Gaps = 37/1271 (2%)
Frame = +1
Query: 94 KLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVD 273
K T +F Y D++ L ++A++ GA PL ++ G + F
Sbjct: 78 KATYGTLFRYATRNDMIFLAIVSLASIAAGAALPLFTVLFGSLAGTF------------- 124
Query: 274 NVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYL 453
L I+ DEFNS + + +Y++ LG+ F YV F E + K+R YL
Sbjct: 125 --RDIALHRITYDEFNSILTRNSLYFVYLGIAQFILLYVSTVGFIYVGEHITQKIRAKYL 182
Query: 454 KAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSW 633
AILRQ I +FDK G +T R+T D +++G+ +K L + + F + + +G+ W
Sbjct: 183 HAILRQNIGFFDKLGAGEVTTRITADTNLIQDGISEKVGLTLTALSTFFSAFIIGYVRYW 242
Query: 634 SMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKR 813
+ L+ ++L +S+ + R+ +Y G +AEE SSIR + G +
Sbjct: 243 KLALICSSTIVAMILVMGGISRFVVKSGRMTLVSYGEGGTVAEEVISSIRNATAF-GTQE 301
Query: 814 ELDRFYNA-LEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGL 990
+L R Y L+ R+ G +GI G MYS+Y L FW GS ++ T D
Sbjct: 302 KLARQYEVHLKEARKWGRRLQMMLGIMFGSMMAIMYSNYGLGFWMGSRFLVGGET-DLSA 360
Query: 991 IFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKG 1170
I + A++ GS S+G P+ +F +A A + + I+ IDP S EG ++N++G
Sbjct: 361 IVNILLAIVIGSFSIGNVAPNTQAFASAISAGAKIFSTIDRVSAIDPGSDEGDTIENVEG 420
Query: 1171 DISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGR 1350
I F+ + YPSR ++ V++ I+L + G ALVG SG GKST+V LL+RFY+P G
Sbjct: 421 TIEFRGIKHIYPSRPEVVVMEDINLVVPKGKTTALVGPSGSGKSTVVGLLERFYNPVSGS 480
Query: 1351 VLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMG---------NEHATHDQVV 1503
VL+DG D++ +N+ LR+QI +VSQEP LF TI+ENI++G +E +++V
Sbjct: 481 VLLDGRDIKTLNLRWLRQQISLVSQEPTLFGTTIFENIRLGLIGSPMENESEEQIKERIV 540
Query: 1504 EACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSAL 1683
A K ANA+DFI LPDGY T VG++G LSGGQKQRIAIARA+V +PKILLLDEATSAL
Sbjct: 541 SAAKEANAHDFIMGLPDGYATDVGQRGFLLSGGQKQRIAIARAIVSDPKILLLDEATSAL 600
Query: 1684 DTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGI 1863
DT++E VQ ALD A GRTTI++AHRLSTI++ D I V G I E G+H+EL+ K+G
Sbjct: 601 DTKSEGVVQAALDAASRGRTTIVIAHRLSTIKSADNIVVIVGGRIAEQGTHDELVDKKGT 660
Query: 1864 FYDMTXX---------XXXXXXXXEAGKDIEDTISESAHS-----------HLXXXXXXX 1983
+ + E K+I IS A S
Sbjct: 661 YLQLVEAQKINEERGEESEDEAVLEKEKEISRQISVPAKSVNSGKYPDEDVEANLGRIDT 720
Query: 1984 XXXXXXXXIHQLAEEVEECKAPPTSMFK-IFKFNGDKVGWXXXXXXXXXXXXSVTPVFAL 2160
+ Q + +E + ++ + I FN + + PV ++
Sbjct: 721 KKSLSSVILSQKRSQEKETEYSLGTLIRFIAGFNKPERLIMLCGFFFAVLSGAGQPVQSV 780
Query: 2161 VYAEIFNVYSLPAD---QMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLR 2331
+A+ SLP +++ + FW MF+++G+ V C ESL + R
Sbjct: 781 FFAKGITTLSLPPSLYGKLREDANFWSLMFLMLGLVQLVTQSAQGVIFAICSESLIYRAR 840
Query: 2332 FEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVF-TRLPVVLASIVTICGALGI 2508
++F+ +LRQDIAF+D + TG L + +T+ ++ V L +L T+ AL +
Sbjct: 841 SKSFRAMLRQDIAFFDLPENSTGALTSFLSTETKHLSGVSGATLGTILMVSTTLIVALTV 900
Query: 2509 GFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHS 2688
+GW+ + G++ + Q R + E + A +A IRTV S
Sbjct: 901 ALAFGWKLALVCISTVPVLLLCGFYRFWILAQFQTRAKKAYESSASYACEATSSIRTVAS 960
Query: 2689 LNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAM 2868
L R++ Y L + +L+ ++A SQS FF A F+ G + +
Sbjct: 961 LTREQGVMEIYEGQLNDQAKKSLRSVAKSSLLYAASQSFSFFCLALGFWYGGGLLGKGEY 1020
Query: 2869 QPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVK 3045
+ + F Q G SF PD+ KA+ AA+ L + ID S G ++
Sbjct: 1021 NAFQFFLCISCVIFGSQSAGIVFSFSPDMGKAKSAAADFKRLFDRVPTIDIESTDGEKLE 1080
Query: 3046 PITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQ 3225
+ G I R+V F YPTR + VL+G L +K G+ +ALVG SGCGKST + L+ERFY+
Sbjct: 1081 TVEGTIEFRDVHFRYPTRPEQPVLRGLNLTVKPGQYIALVGPSGCGKSTTIALVERFYDT 1140
Query: 3226 DKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNR-NVTYQEIVEAA 3402
G + IDG +I LN++S R + +VSQEPTL+ TI +N+ G +R +V +++ A
Sbjct: 1141 LSGGVYIDGKDISRLNVNSYRSHLALVSQEPTLYQGTIRDNVLLGVDRDDVPDEQVFAAC 1200
Query: 3403 KMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTE 3582
K ANI++FI+ LPDG+ T VG KG+ LSGGQKQRIAIARAL+R P VLLLDEATSALD+E
Sbjct: 1201 KAANIYDFIMSLPDGFGTVVGSKGSMLSGGQKQRIAIARALIRDPKVLLLDEATSALDSE 1260
Query: 3583 SEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQK 3762
SEK+VQ ALDAA +GRT + +AHRLSTIQ +D+I + +G+IVE GTH EL++ Y +
Sbjct: 1261 SEKVVQAALDAAAKGRTTIAVAHRLSTIQKADIIYVFDQGRIVESGTHHELLQNKGRYYE 1320
Query: 3763 FCETQRIVESQ 3795
Q + ++Q
Sbjct: 1321 LVHMQSLEKTQ 1331
>gi|39594940|emb|CAE70808.1| Hypothetical protein CBG17570
[Caenorhabditis briggsae]
Length = 1402
Score = 754 bits (1947), Expect = 0.0
Identities = 446/1223 (36%), Positives = 679/1223 (55%), Gaps = 10/1223 (0%)
Frame = +1
Query: 124 TQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPI 303
T ++ LL + GT++AV G P L+ G ++ VF+R ++ VN L P
Sbjct: 32 TSKLEKLLFLLGTISAVCTGLCQPFLSYTFGEVSHVFVRITSA--------VNNRTLDPS 83
Query: 304 SLDE----FNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
LDE F++E+ + +Y+ ++G + Q + F+ + +++R+ Y+ +L++
Sbjct: 84 ELDEAYEVFHNEMNQVVLYFALVGCAFAMFGFFQFSLFKYVGDNTTYRVRRKYISRLLQK 143
Query: 472 QIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVM 651
Q+FD TG L+ L D+LER RE +K A ++ F+ G + F+ W +
Sbjct: 144 DAQYFDTVSTGYLSTVLNDNLERFREAFNEKIAFIICFSTDFVIGTTLAFYTDWKLASYG 203
Query: 652 MGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFY 831
FA I SG S SM T + YA AGAIA + SS +TV SLNG +EL+R+
Sbjct: 204 SIFALGIAFSGFINSASMMGSTVKQNTHYANAGAIAFQALSSFKTVISLNGQAQELERYS 263
Query: 832 NALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFA 1011
L+ G + G + ++ ++ + + + G+ LI N T D+ +I T+F
Sbjct: 264 KELKAGEKYGARRAFFLATSRSVTHFFCNALNGIILYVGADLIYNK-TMDQAVIVTLFHY 322
Query: 1012 VLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDN--MKGDISFK 1185
+L + SLG A PH++ A +AS + V+ S I D+ ++GDI F
Sbjct: 323 MLFSAFSLGEAFPHISYLSNAISSASPIFAVLISKDDIIENHQNDTERDSERIEGDIQFD 382
Query: 1186 DVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDG 1365
+V F YP+R + LKG++ +K G+ +ALVG+SG GKSTIV LL +Y+ G +LID
Sbjct: 383 NVKFSYPTRPEAQALKGVTFNVKKGECVALVGASGSGKSTIVQLLLHYYNIESGNILIDD 442
Query: 1366 VDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKR 1545
VDL ++N+ LR IG+VSQEPVLF+ TI ENI+ GN A+ ++ ++ ++ANA DF+
Sbjct: 443 VDLNKINLKKLRGNIGVVSQEPVLFNTTIEENIRFGNPAASTLEIYDSLRVANAYDFVNS 502
Query: 1546 LPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQ 1725
P G T VGE+G QLSGGQKQRIAIAR LVKNPKILLLDEATSALD ++E V+ A+ +
Sbjct: 503 FPKGIKTVVGERGTQLSGGQKQRIAIARVLVKNPKILLLDEATSALDNQSEHVVRIAMKE 562
Query: 1726 AQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXX 1905
A GRTTI++AHRLSTI++ DRI V G V SG+H++LM ++ D+
Sbjct: 563 ASKGRTTIVIAHRLSTIQHCDRIIVMSHGKTVASGTHDKLMENSIVYKDLVQAQSLNSED 622
Query: 1906 XEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKAPPT---SMFKIFK 2076
K I+ TI+ S H +L EE+++ T ++++I +
Sbjct: 623 SVVEKSIK-TIATSETKHPTN--------------EELEEELKDTPEEETMSSTIWQILR 667
Query: 2077 FNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANVYFWCGMFVLMGI 2256
P+ A + ++ Y++ + + N +FW MF+++G+
Sbjct: 668 ECRSHCCMLFLAVVGSAIQGFSFPILAQLIVRVYKAYAMQGEAILVNGHFWASMFLVLGL 727
Query: 2257 TFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPN 2436
+ + G+ GE L+ +LR ++F++LL AFYDD ++ +L R TDA N
Sbjct: 728 YRPITLYCQYFFFGKIGEKLSTRLRIKSFQHLLSLPCAFYDDPKNSPTRLANRLNTDASN 787
Query: 2437 VR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQI 2613
V+ V RL VL ++V+ A+ I YY W+ + Y +
Sbjct: 788 VKAAVDARLGSVLMTLVSFIVAITIACYYSWKLTIQVLLFFPVLYLSKYCYEKTTVLSIK 847
Query: 2614 RDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAF 2793
+D+ E + K+A + +++I+TV SLN +++ L K A G F
Sbjct: 848 QDSLAFEFSNKIAIEVLDNIKTVRSLNMEQKVMSMVTGQLEMLKRKYHKRAFFLGLASGF 907
Query: 2794 SQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLA 2973
S +YA +F G+ + Q+ + P+D+Y +S+ M G+ S++PD KA A
Sbjct: 908 SAGCSQIVYALSFKFGTYLILQREVLPMDMYLALVTLSYTSNMAGSAISYLPDYKKALHA 967
Query: 2974 ASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKT 3153
A L+F L +P SD G G ++ NV F+Y R D VL+ L ++ GKT
Sbjct: 968 AGLIFNLFTYPATAPYNSDQGTTNISQGIVNAENVKFHYHQRPDHLVLKNVDLHLEPGKT 1027
Query: 3154 VALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDC 3333
+ALVG SG GKST + LLE FY + G I ID +N+ N+N+ LR + +VSQEP LF+C
Sbjct: 1028 LALVGPSGSGKSTFISLLEMFYRVNTGHINIDHENVENINLHHLRSNLALVSQEPILFNC 1087
Query: 3334 TIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAI 3513
+I EN+ YG + + Q + A + AN +NF+ +P+G DT VGE+G QLSGGQKQR+AI
Sbjct: 1088 SIRENLLYGLDGPESDQNLETALETANAYNFVSQMPNGLDTIVGERGAQLSGGQKQRVAI 1147
Query: 3514 ARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIV 3693
ARA++R+P +LLLDEATSALD++SEK+VQ ALD A + + +++AHRLSTI N+D IA++
Sbjct: 1148 ARAILRNPKLLLLDEATSALDSDSEKLVQTALDTASERLSTIIVAHRLSTIVNADSIAVL 1207
Query: 3694 SEGKIVEKGTHDELIRKSEIYQK 3762
GK+VE+G+H+EL++ Y K
Sbjct: 1208 KMGKVVEQGSHEELLKLKGAYWK 1230
Score = 312 bits (799), Expect = 4e-83
Identities = 183/512 (35%), Positives = 287/512 (55%), Gaps = 3/512 (0%)
Frame = +1
Query: 349 YLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD--KQQTGNLTARL 522
+LVLG+ T Y Q F E+L +LR + +L ++D K L RL
Sbjct: 722 FLVLGLYRPITLYCQYFFFGKIGEKLSTRLRIKSFQHLLSLPCAFYDDPKNSPTRLANRL 781
Query: 523 TDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKS 702
D V+ + + ++ +F+ + +YSW +T+ ++ F P++ LS K+
Sbjct: 782 NTDASNVKAAVDARLGSVLMTLVSFIVAITIACYYSWKLTIQVLLFFPVLYLSKYCYEKT 841
Query: 703 MATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYM 882
+ + + + IA E +I+TV SLN ++ + LE+ ++ + ++
Sbjct: 842 TVLSIKQDSLAFEFSNKIAIEVLDNIKTVRSLNMEQKVMSMVTGQLEMLKRKYHKRAFFL 901
Query: 883 GIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLAS 1062
G+ GFS C YAL+F +G+ LI+ + + + S G A+ +L
Sbjct: 902 GLASGFSAGCSQIVYALSFKFGTYLILQREVLPMDM-YLALVTLSYTSNMAGSAISYLPD 960
Query: 1063 FGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGIS 1242
+ A AA + + ++P PY+ + + +G ++ ++V F Y R D VLK +
Sbjct: 961 YKKALHAAGLIFNLF-TYPATAPYNSDQGTTNISQGIVNAENVKFHYHQRPDHLVLKNVD 1019
Query: 1243 LELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVS 1422
L L+ G +ALVG SG GKST ++LL+ FY G + ID ++ +N+H LR + +VS
Sbjct: 1020 LHLEPGKTLALVGPSGSGKSTFISLLEMFYRVNTGHINIDHENVENINLHHLRSNLALVS 1079
Query: 1423 QEPVLFDGTIYENIKMGNEHATHDQVVE-ACKMANANDFIKRLPDGYGTRVGEKGVQLSG 1599
QEP+LF+ +I EN+ G + DQ +E A + ANA +F+ ++P+G T VGE+G QLSG
Sbjct: 1080 QEPILFNCSIRENLLYGLDGPESDQNLETALETANAYNFVSQMPNGLDTIVGERGAQLSG 1139
Query: 1600 GQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIR 1779
GQKQR+AIARA+++NPK+LLLDEATSALD+++E+ VQ ALD A +TIIVAHRLSTI
Sbjct: 1140 GQKQRVAIARAILRNPKLLLLDEATSALDSDSEKLVQTALDTASERLSTIIVAHRLSTIV 1199
Query: 1780 NVDRIFVFKAGNIVESGSHEELMSKQGIFYDM 1875
N D I V K G +VE GSHEEL+ +G ++ +
Sbjct: 1200 NADSIAVLKMGKVVEQGSHEELLKLKGAYWKL 1231
Score = 289 bits (740), Expect = 3e-76
Identities = 191/554 (34%), Positives = 289/554 (51%), Gaps = 15/554 (2%)
Frame = +1
Query: 2167 AEIFNVYSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFK 2346
+E+ Y + ++M V + F L+G F + F + G++ T ++R +
Sbjct: 83 SELDEAYEVFHNEMNQVVLY----FALVGCAFAMFGFFQFSLFKYVGDNTTYRVRRKYIS 138
Query: 2347 NLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVFT-RLPVVLASIVTICGALGIGFYYG 2523
LL++D ++D + TG L T + R F ++ ++ + FY
Sbjct: 139 RLLQKDAQYFDTV--STGYLSTVLNDNLERFREAFNEKIAFIICFSTDFVIGTTLAFYTD 196
Query: 2524 WQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQE 2703
W+ G+ G ++ AG +A QA+ +TV SLN Q
Sbjct: 197 WKLASYGSIFALGIAFSGFINSASMMGSTVKQNTHYANAGAIAFQALSSFKTVISLNGQA 256
Query: 2704 QFHFTYCEYLREPFNTNLKHAHTYGAVFAF----SQSLIFFMYAAA----FYLGSIFVNQ 2859
Q E ++ LK YGA AF S+S+ F A Y+G+ +
Sbjct: 257 QE--------LERYSKELKAGEKYGARRAFFLATSRSVTHFFCNALNGIILYVGADLIYN 308
Query: 2860 QAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPI------DS 3021
+ M + +F + F +G I + A +AS +F ++ I D+
Sbjct: 309 KTMDQAVIVTLFHYMLFSAFSLGEAFPHISYLSNAISSASPIFAVLISKDDIIENHQNDT 368
Query: 3022 LSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMG 3201
DS + I G+I NV F+YPTR + + L+G T ++K G+ VALVG SG GKSTI+
Sbjct: 369 ERDS---ERIEGDIQFDNVKFSYPTRPEAQALKGVTFNVKKGECVALVGASGSGKSTIVQ 425
Query: 3202 LLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTY 3381
LL +YN + G I+ID ++ +N+ LR + +VSQEP LF+ TI ENI +G N +
Sbjct: 426 LLLHYYNIESGNILIDDVDLNKINLKKLRGNIGVVSQEPVLFNTTIEENIRFG-NPAAST 484
Query: 3382 QEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEA 3561
EI ++ ++AN ++F+ P G T VGE+GTQLSGGQKQRIAIAR LV++P +LLLDEA
Sbjct: 485 LEIYDSLRVANAYDFVNSFPKGIKTVVGERGTQLSGGQKQRIAIARVLVKNPKILLLDEA 544
Query: 3562 TSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIR 3741
TSALD +SE +V+ A+ A +GRT +VIAHRLSTIQ+ D I ++S GK V GTHD+L+
Sbjct: 545 TSALDNQSEHVVRIAMKEASKGRTTIVIAHRLSTIQHCDRIIVMSHGKTVASGTHDKLME 604
Query: 3742 KSEIYQKFCETQRI 3783
S +Y+ + Q +
Sbjct: 605 NSIVYKDLVQAQSL 618
>gi|50556486|ref|XP_505651.1| hypothetical protein [Yarrowia
lipolytica]
gi|49651521|emb|CAG78460.1| unnamed protein product [Yarrowia
lipolytica CLIB99]
Length = 1326
Score = 754 bits (1947), Expect = 0.0
Identities = 465/1251 (37%), Positives = 677/1251 (53%), Gaps = 20/1251 (1%)
Frame = +1
Query: 91 VKLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGV 270
VK+ +F Y +D+ +L G V A G PL ++ G MT FL F+V
Sbjct: 108 VKVNFLTLFRYATKLDIFILFIGMVTAAAAGVCMPLFTVIFGQMTNEFLA-----FIV-- 160
Query: 271 DNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNY 450
+ S D F ++ Y +Y++ + V F + ++ ERL ++R+NY
Sbjct: 161 --------LGSSADRFQHQINHYALYFVYIAVATFCLTSIKTYITVERGERLSARIRENY 212
Query: 451 LKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYS 630
LKAI+RQ I +FDK G +T R+T D ++EG+ +K L+V ++F+ +GF S
Sbjct: 213 LKAIMRQNIGYFDKLGAGEVTNRITTDTNLIQEGISEKLGLIVSAVSSFITSLVIGFIKS 272
Query: 631 WSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHK 810
+T +M+ +VL+ S + R E + +IAEE F+SI + +
Sbjct: 273 ARLTGIMISTVVALVLAMGICSTFLVRYVRWAIEDDSECSSIAEECFASITNIVAFGMQV 332
Query: 811 RELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGL 990
+ R+ L + ++K +G VG Y YALA W GS L+ T G
Sbjct: 333 KMDKRYEKPLNSSLKNYLLKARVLGAMVGILWCITYCMYALALWEGSRLVNKGET-SIGH 391
Query: 991 IFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKG 1170
+ TV A++ G+ LGG P++ S G+A GA + I+ P ID S G + N++G
Sbjct: 392 VITVLMALMIGAFQLGGVAPNMESLGSAVGAGKKIFETIDRVPDIDSLS-GGETLSNLRG 450
Query: 1171 DISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGR 1350
ISFK+VHFRYPSR + +L+ +L++ +G +ALVG+SG GKSTIV LL+RFY P G
Sbjct: 451 AISFKNVHFRYPSRPTVPILREFNLDIPSGATVALVGASGSGKSTIVALLERFYQPLGGS 510
Query: 1351 VLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIK---MGNEHATHDQVV------ 1503
+ +DGV + ++V LR+Q+ +VSQEP LF+ TI+ENI +G E+ ++ V
Sbjct: 511 ITVDGVSILSLDVKWLRQQMSLVSQEPTLFNCTIFENISHGLIGTEYENAERSVKMKLVE 570
Query: 1504 EACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSAL 1683
+AC+ AN ++FIK L DG T+VGEKG LSGGQKQR+AIARA++ NP ILLLDEATSAL
Sbjct: 571 DACEQANCSEFIKTLTDGLDTQVGEKGYLLSGGQKQRVAIARAIISNPPILLLDEATSAL 630
Query: 1684 DTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGI 1863
DT +E+ VQ ALD+A RTTI++AHRLSTI+N D+I V G I+E GSH+EL++ +G
Sbjct: 631 DTRSEKLVQQALDKAAKNRTTIVIAHRLSTIKNADKIVVMSKGEILEQGSHDELIAARGT 690
Query: 1864 FYDMTXXXXXXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECK 2043
+Y + + IED E+A + V K
Sbjct: 691 YYGLV-----------GAQRIEDGGPETA----STTEKGYYWESGSGSDFDVGSNVSVEK 735
Query: 2044 APPTSMFKIFK----FNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEI---FNVYSLPAD 2202
P + + + K FN ++ + P AL+Y + F V L
Sbjct: 736 TTPLNTWGMIKLLARFNRNERLPLLLGSGFAVICGAGYPSLALLYGSVMQAFMVDPLAYK 795
Query: 2203 QMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDD 2382
M + + G F ++G+ +F LG E+L L+ F +LL QD+ F+D
Sbjct: 796 HMLHEIDKFSGFFFMVGMVQLGSYFMQVYYLGVASETLVRNLKRTIFSHLLNQDLRFFDT 855
Query: 2383 LRHGTGKLCTRFATDAPNVRYV-FTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXX 2559
TGKL + + D NV+ + +L+SIVT+ ++ + Y W+
Sbjct: 856 TT--TGKLTSSLSKDTQNVQGLGGATFGQILSSIVTVIISVILSCCYTWKLGLVCSACIP 913
Query: 2560 XXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLRE 2739
G+F + R ++ E + A +A +I+TV +L R++ Y +
Sbjct: 914 LILSSGFFRFYILTQLNQRGRKVYESSAGYACEATNNIQTVMALTREDDVLNFYSSKVNN 973
Query: 2740 PFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQ 2919
+ K +F SQ+LI + A F+ GS + ++ + + F + F Q
Sbjct: 974 VVYHSAKSNAISSMLFGASQTLIILINALGFWYGSTLIRKREIDINQFFVAFVTVVFGVQ 1033
Query: 2920 MIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGI---VKPITGNISIRNVFFNY 3090
G+ SF PD+ KA++A + +++ I +SG+ + + GNIS NV F Y
Sbjct: 1034 SAGSIFSFTPDMGKAKVATQSIHEILKVKPEIGGDKESGLSLDPEKVVGNISFDNVRFRY 1093
Query: 3091 PTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNL 3270
P R VLQG +L I AG VALVG SGCGKST + L+ERFY+ +G I IDG +IR+L
Sbjct: 1094 PERPKIPVLQGLSLSIPAGSYVALVGSSGCGKSTTISLIERFYDVLQGSITIDGIDIRDL 1153
Query: 3271 NISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGY 3450
N+ S R + +V QEP LF TI ENI G +V + AA ANIHNF++ LPDGY
Sbjct: 1154 NLGSYRSLISLVQQEPILFSGTIRENILLGAEGDVDDATLHSAAIQANIHNFVMSLPDGY 1213
Query: 3451 DTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGR 3630
DT G KGT LSGGQKQR+AIARAL+R P +LLLDEATSALD+ESEK+VQ+ALD A QGR
Sbjct: 1214 DTFCGNKGTLLSGGQKQRVAIARALIRDPKILLLDEATSALDSESEKVVQQALDTAAQGR 1273
Query: 3631 TCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRI 3783
T + +AHRLSTIQN+D I ++ +GK++E+GTH L+ K Y + + Q +
Sbjct: 1274 TTIAVAHRLSTIQNADSIYVLEDGKVLEQGTHSHLMAKKGRYYELVKLQAL 1324
>gi|393116|gb|AAA93553.1| P-glycoprotein 5
Length = 1301
Score = 752 bits (1942), Expect = 0.0
Identities = 468/1289 (36%), Positives = 706/1289 (54%), Gaps = 68/1289 (5%)
Frame = +1
Query: 94 KLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVG-- 267
K++ +F Y+ +D++LL+ G ++++ +G PL+ +++G M ++ + ++
Sbjct: 33 KVSVIKLFKYSDWIDMILLVVGLISSIGNGVMQPLMMLLMGDMVNSYIYTPGDNTIIDEE 92
Query: 268 VDNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQN 447
V+++ EG+ + N VVK IYY V+ +++ S+++ ++R ++R+
Sbjct: 93 VNHMIVEGVK----ESENKVVVKNGIYYEVISMVL---SFLRTFSLFVVSQREGIRVRRL 145
Query: 448 YLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFY 627
Y K++LRQ W+D Q++G LTAR+ D++ ++G+G KF ++ Q+ + + G + F
Sbjct: 146 YFKSLLRQDATWYDFQESGELTARIATDIKNYQDGIGPKFGMIFQIISMVITGCVIEFKK 205
Query: 628 SWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGH 807
W + LV++ P S + + AGAIAEET +IRTV SLN
Sbjct: 206 CWDLALVVLATVPFSSFSFTIFQIIGMKYETKALKVFGAAGAIAEETIGNIRTVQSLNQK 265
Query: 808 KRELDRFYNALEVGRQ-TGIVKYCYMG-IGVGFSNLCMYSSYALAFWYGSTLIINDPTFD 981
+ + ++ GI C M I M +SYAL WYGS L+I
Sbjct: 266 NEFIAEYQEKIKQNEHFNGIKGQCLMSWIRFSVITFFMIASYALGSWYGS-LVIRGKGGS 324
Query: 982 RGL----IFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGI 1149
+G+ + TVF +VLS S +L L + + +A + I+ P ID S+ G
Sbjct: 325 KGVFAGHVLTVFLSVLSASQTLSMIAILLNLLFSDKASAYKIFTTIDRIPDIDCQSIGGE 384
Query: 1150 LVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRF 1329
G+I F DV F YP+R HVLKG+ +E+K G+ IALVG+SGCGKST + L+QR
Sbjct: 385 CPTECNGNIRFVDVQFVYPTRPSHHVLKGLDIEIKKGETIALVGASGCGKSTTIQLIQRN 444
Query: 1330 YDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMG---NEHATHDQV 1500
Y+P GRV +DG D+RE+N+ LR QIG+V QE VLF GTI ENI +G E + D++
Sbjct: 445 YEPNGGRVTLDGKDIRELNIKWLRNQIGLVGQESVLFSGTIRENIMLGAKEGETLSKDEM 504
Query: 1501 VEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSA 1680
+E K+ANA +F+ +L +GY T +GEKG LSGGQKQRIAIARAL++NP ILLLDEATSA
Sbjct: 505 IECAKVANAYEFVSKLAEGYDTLIGEKGALLSGGQKQRIAIARALIRNPSILLLDEATSA 564
Query: 1681 LDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQG 1860
LDT++E+ VQ AL++A GRTTIIVAHRL+T+RN D+I VF G I+E G H+EL+ +G
Sbjct: 565 LDTQSEKIVQEALEKASKGRTTIIVAHRLTTVRNADQICVFHQGEIIEQGKHQELIDLKG 624
Query: 1861 IFYDM-------------TXXXXXXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXX 2001
+Y + T + K++E+ I E +H
Sbjct: 625 TYYGLVKGQSMEEEVEQETVENDIKKFRKQEDKEVENIIVEESHDE----------EEEE 674
Query: 2002 XXIHQLAEEVEECK--APPTSMFKIFKFNGDKVGW----XXXXXXXXXXXXSVTPVFALV 2163
+ ++ EE E+ K + F I + +++ +V P+F +
Sbjct: 675 DIVSKIKEEYEKEKKIRKKRNRFSIIRIMIEQLRMNFVLFILATIGGIVGGAVFPIFTIK 734
Query: 2164 YAEIFNVYSLPADQMQ---------ANVYFWCGMFVLMGITF--------FVGFFTSANC 2292
+ ++ + D ++ N W +MGI F ++G F S+
Sbjct: 735 FIDLIVMMMELQDGVELTDEQQHTLVNTIIW-----VMGIAFAGLLSTYCYIGIFASS-- 787
Query: 2293 LGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVFTRLPVVL 2472
E L +R FK++++Q+I ++D + G L TR ++D + + V+L
Sbjct: 788 ----AEYLIGSVRRRMFKSIVKQEIGWFDRKENRVGSLVTRLSSDPTKLNGI---TGVIL 840
Query: 2473 ASIV----TICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEA 2640
IV TIC A G YY W+ + +F+ ++ + + EE+
Sbjct: 841 GHIVYILSTICFAFGFALYYDWKLALCVIAVFPIHTLILFFDFKLNSMQSSPAEKAYEES 900
Query: 2641 GKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMY 2820
G +AVE ++TV SL R+E F Y L++P+ + K V A + F +
Sbjct: 901 GITLVEAVESMKTVQSLTREEYFLKQYSLNLKKPYKSIFKWGLILALVNAITNLSNFIVD 960
Query: 2821 AAAFYLGSIFV---------NQQAMQP-----IDVYRVFFAISFCGQMIGNTTSFIPDVV 2958
A +YLG+ + NQ Q + + + ++ F +GN IPD+
Sbjct: 961 AYGYYLGTYLLAKNLNYTQTNQGFYQEFMDRYMKIQKAIMSVVFAAHGVGNFGEIIPDIG 1020
Query: 2959 KARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTKVLQGFTLD 3135
K+ AA + LI+ IDS +G + G I +N+ F YPTR D +VL+G +
Sbjct: 1021 KSMKAARHSYNLIDRNAKIDSSEINGNTFNDVKGEIEFKNIRFRYPTRADNEVLKGISFK 1080
Query: 3136 IKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQE 3315
GKT+ALVG SGCGKST + L+ERFY+ G +++DG NI++LN+ LR Q+ +V QE
Sbjct: 1081 ADQGKTIALVGASGCGKSTTIQLVERFYDPTSGEVLLDGYNIKDLNVKFLRNQIGLVGQE 1140
Query: 3316 PTLFDCTIGENICYGTNR--NVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSG 3489
P LF ++ +NI G V+ ++I AAKMAN H+FI +P+GY+T VG++G+QLSG
Sbjct: 1141 PVLFAESVIDNIKRGVPEGVEVSNEQIYAAAKMANAHDFISAMPEGYNTMVGDRGSQLSG 1200
Query: 3490 GQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQ 3669
GQKQRIAIARAL+R+P VLLLDEATSALDT+SEKIVQ+ALD A +GRT ++IAHRLSTIQ
Sbjct: 1201 GQKQRIAIARALIRNPKVLLLDEATSALDTQSEKIVQDALDKASKGRTTIIIAHRLSTIQ 1260
Query: 3670 NSDVIAIVSEGKIVEKGTHDELIRKSEIY 3756
N+D I ++ GKIVE+GTH EL+ Y
Sbjct: 1261 NADQICVIMRGKIVEQGTHQELMDLKGFY 1289
Score = 366 bits (940), Expect = 2e-99
Identities = 219/603 (36%), Positives = 340/603 (56%), Gaps = 22/603 (3%)
Frame = +1
Query: 133 VDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLD 312
++ +L I T+ ++ GA FP+ I + + + Q+ GV+ D
Sbjct: 709 MNFVLFILATIGGIVGGAVFPIFTIKFIDLIVMMMELQD-----GVELT----------D 753
Query: 313 EFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDK 492
E +V I+ + + ++Y I F S AE L+ +R+ K+I++Q+I WFD+
Sbjct: 754 EQQHTLVNTIIWVMGIAFAGLLSTYCYIGIFASSAEYLIGSVRRRMFKSIVKQEIGWFDR 813
Query: 493 QQT--GNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAP 666
++ G+L RL+ D ++ G +V + + +G +Y W + L ++ P
Sbjct: 814 KENRVGSLVTRLSSDPTKLNGITGVILGHIVYILSTICFAFGFALYYDWKLALCVIAVFP 873
Query: 667 LIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEV 846
+ L K + ++ ++ Y +G E S++TV SL + L ++ L+
Sbjct: 874 IHTLILFFDFKLNSMQSSPAEKAYEESGITLVEAVESMKTVQSLTREEYFLKQYSLNLKK 933
Query: 847 GRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTF------------DRGL 990
++ + + +NL + A ++ G+ L+ + + DR +
Sbjct: 934 PYKSIFKWGLILALVNAITNLSNFIVDAYGYYLGTYLLAKNLNYTQTNQGFYQEFMDRYM 993
Query: 991 -----IFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILV 1155
I +V FA G + G +P + G + AA +I+ + KID + G
Sbjct: 994 KIQKAIMSVVFAA-HGVGNFGEIIPDI---GKSMKAARHSYNLIDRNAKIDSSEINGNTF 1049
Query: 1156 DNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYD 1335
+++KG+I FK++ FRYP+R D VLKGIS + G IALVG+SGCGKST + L++RFYD
Sbjct: 1050 NDVKGEIEFKNIRFRYPTRADNEVLKGISFKADQGKTIALVGASGCGKSTTIQLVERFYD 1109
Query: 1336 PTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMG---NEHATHDQVVE 1506
PT G VL+DG +++++NV LR QIG+V QEPVLF ++ +NIK G +++Q+
Sbjct: 1110 PTSGEVLLDGYNIKDLNVKFLRNQIGLVGQEPVLFAESVIDNIKRGVPEGVEVSNEQIYA 1169
Query: 1507 ACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALD 1686
A KMANA+DFI +P+GY T VG++G QLSGGQKQRIAIARAL++NPK+LLLDEATSALD
Sbjct: 1170 AAKMANAHDFISAMPEGYNTMVGDRGSQLSGGQKQRIAIARALIRNPKVLLLDEATSALD 1229
Query: 1687 TEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIF 1866
T++E+ VQ ALD+A GRTTII+AHRLSTI+N D+I V G IVE G+H+ELM +G +
Sbjct: 1230 TQSEKIVQDALDKASKGRTTIIIAHRLSTIQNADQICVIMRGKIVEQGTHQELMDLKGFY 1289
Query: 1867 YDM 1875
Y +
Sbjct: 1290 YTL 1292
Score = 291 bits (745), Expect = 8e-77
Identities = 188/504 (37%), Positives = 276/504 (54%), Gaps = 14/504 (2%)
Frame = +1
Query: 2320 MKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPN----VRYVFTRLPVVLASIVT 2487
+++R FK+LLRQD +YD +G+L R ATD N + F + +++ ++T
Sbjct: 140 IRVRRLYFKSLLRQDATWYDFQE--SGELTARIATDIKNYQDGIGPKFGMIFQIISMVIT 197
Query: 2488 ICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVE 2667
C I F W + + + ++ AG +A + +
Sbjct: 198 GCV---IEFKKCWDLALVVLATVPFSSFSFTIFQIIGMKYETKALKVFGAAGAIAEETIG 254
Query: 2668 HIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFM---YAAAFYL 2838
+IRTV SLN++ +F Y E +++ + N + FS + FFM YA +
Sbjct: 255 NIRTVQSLNQKNEFIAEYQEKIKQNEHFNGIKGQCLMSWIRFSV-ITFFMIASYALGSWY 313
Query: 2839 GSIFVN----QQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHP 3006
GS+ + + + V VF ++ Q + + + + +A +F I+
Sbjct: 314 GSLVIRGKGGSKGVFAGHVLTVFLSVLSASQTLSMIAILLNLLFSDKASAYKIFTTIDRI 373
Query: 3007 TPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCG 3183
ID S G GNI +V F YPTR VL+G ++IK G+T+ALVG SGCG
Sbjct: 374 PDIDCQSIGGECPTECNGNIRFVDVQFVYPTRPSHHVLKGLDIEIKKGETIALVGASGCG 433
Query: 3184 KSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGT 3363
KST + L++R Y + G + +DG +IR LNI LR Q+ +V QE LF TI ENI G
Sbjct: 434 KSTTIQLIQRNYEPNGGRVTLDGKDIRELNIKWLRNQIGLVGQESVLFSGTIRENIMLGA 493
Query: 3364 NRNVTYQ--EIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSP 3537
T E++E AK+AN + F+ L +GYDT +GEKG LSGGQKQRIAIARAL+R+P
Sbjct: 494 KEGETLSKDEMIECAKVANAYEFVSKLAEGYDTLIGEKGALLSGGQKQRIAIARALIRNP 553
Query: 3538 SVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEK 3717
S+LLLDEATSALDT+SEKIVQEAL+ A +GRT +++AHRL+T++N+D I + +G+I+E+
Sbjct: 554 SILLLDEATSALDTQSEKIVQEALEKASKGRTTIIVAHRLTTVRNADQICVFHQGEIIEQ 613
Query: 3718 GTHDELIRKSEIYQKFCETQRIVE 3789
G H ELI Y + Q + E
Sbjct: 614 GKHQELIDLKGTYYGLVKGQSMEE 637
>gi|4204793|gb|AAD10836.1| P-glycoprotein [Solanum tuberosum]
Length = 1313
Score = 751 bits (1940), Expect = 0.0
Identities = 447/1259 (35%), Positives = 680/1259 (53%), Gaps = 31/1259 (2%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F + G+D +L+I G++ A +HG PL FLR D VN G
Sbjct: 58 LFRFADGLDCVLMIIGSLGAFVHGCSLPL-----------FLR-------FFADLVNSFG 99
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
+D+ EV+KY Y+LV+G ++ +S+ +I+C+ ER K+R YL+A L Q
Sbjct: 100 SYANDVDKMTQEVLKYAFYFLVVGAAIWASSWAEISCWMWTGERQTTKMRIKYLEAALNQ 159
Query: 472 QIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLV 648
IQ+FD + +T ++ + + D V++ + +K + A FL+G+ VGF W + LV
Sbjct: 160 DIQYFDTEVRTSDVVSAINTDAVVVQDAISEKLGNFIHYMATFLSGFVVGFTAVWQLALV 219
Query: 649 MMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRF 828
+ PLI + GA + + A + QE + AG I E+T IRTV G + L +
Sbjct: 220 TLAVVPLIAVIGAIYTVTSAKLSSQSQEALSKAGNIVEQTVVQIRTVLVFVGEAKALQAY 279
Query: 829 YNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFF 1008
AL V ++ G G+G+G + ++ YAL WYG L+ + T + GL F
Sbjct: 280 TAALRVSQKIGYKSGFSKGLGLGATYFTVFCCYALLLWYGGYLVRHHFT-NGGLAIATMF 338
Query: 1009 AVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKD 1188
AV+ G +LG + P + +F AR AA+ + R+I+ P +D + G+ +D + G + K+
Sbjct: 339 AVMIGGLALGQSAPSMTAFAKARVAAAKIFRIIDHKPSVDRNAKTGLELDTVSGQLELKN 398
Query: 1189 VHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGV 1368
V F YPSR +I +L +L + AG IALVGSSG GKST+V+L++RFYDPT G++++DG
Sbjct: 399 VEFSYPSRPEIKILNNFNLVVPAGKTIALVGSSGSGKSTVVSLIERFYDPTSGQLMLDGN 458
Query: 1369 DLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRL 1548
D++ + + LR+QIG+VSQEP LF +I ENI +G AT ++ EA ++ANA+ F+ +L
Sbjct: 459 DIKTLKLKWLRQQIGLVSQEPALFATSIKENILLGRPDATQIEIEEAARVANAHSFVIKL 518
Query: 1549 PDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQA 1728
PDG+ T+VGE+G+QLSGGQKQRIAIARA++KNP ILLLDEATSALD+E+E+ VQ ALD+
Sbjct: 519 PDGFDTQVGERGLQLSGGQKQRIAIARAMLKNPAILLLDEATSALDSESEKLVQEALDRF 578
Query: 1729 QAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSK--QGIFYD---------- 1872
GRTT+++AHRLSTIR D + V + G++ E GSH+ELMSK G++
Sbjct: 579 MIGRTTLVIAHRLSTIRKADLVAVLQQGSVSEIGSHDELMSKGENGMYAKLIKMQEAAHE 638
Query: 1873 --MTXXXXXXXXXXEAGKDIEDTISESAHSH--------LXXXXXXXXXXXXXXXIHQLA 2022
++ A + I S+ L
Sbjct: 639 TALSNARKSSARPSSARNSVSSPIITRNSSYGRSPYSRRLSDFSTSDFSLSLDAAYSNYR 698
Query: 2023 EEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPAD 2202
E K +S ++ K N + + S++ FA V + + +VY P
Sbjct: 699 NEKLAFKDQASSFGRLAKMNSPEWTYALIGSIGSVICGSLSAFFAYVLSAVLSVYYNPDH 758
Query: 2203 -QMQANVYFWCGMFVLMGITFFVGFFTSAN--CLGRCGESLTMKLRFEAFKNLLRQDIAF 2373
M + +C ++L+G++ F + GE+LT ++R + +L+ ++A+
Sbjct: 759 AYMSEQIAKYC--YLLIGVSSAALIFNTLQHYYWDVVGENLTKRVREKMLAAVLKMEMAW 816
Query: 2374 YDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXX 2550
+D + + ++ R + DA NVR + R+ V++ + + A GF W+
Sbjct: 817 FDQEENDSSRIAARLSLDANNVRSAIGDRISVIMQNSALMLVACTAGFVLQWRLALVLIG 876
Query: 2551 XXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEY 2730
+ G +A ++A +AV ++RTV + N + + +
Sbjct: 877 VFPVVVAATVLQKMFMKGFSGDLEAAHAKATQLAGEAVANVRTVAAFNSETKIVNLFDSS 936
Query: 2731 LREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISF 2910
L+ P G+ + +Q L++ YA + S V RVF +
Sbjct: 937 LQTPLRRCFWKGQIAGSGYGIAQFLLYSSYALGLWYASWLVKHGISDFSKTIRVFMVLMV 996
Query: 2911 CGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPI--DSLSDSGIVKPITGNISIRNVFF 3084
T + PD +K A +F L++ T + D + + + G + ++V F
Sbjct: 997 SANGAAETLTLAPDFIKGGRAMRSVFELLDRKTEVEPDDPDATAVPDRLRGEVEFKHVDF 1056
Query: 3085 NYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIR 3264
+YPTR D + + L +AGKT+ALVG SGCGKS+++ L+ERFY G ++IDG +IR
Sbjct: 1057 SYPTRPDVSIFRDLNLRARAGKTLALVGPSGCGKSSVISLIERFYEPSSGRVIIDGKDIR 1116
Query: 3265 NLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPD 3444
N+ SLR + +V QEP LF TI ENI YG + + T EI EAA +AN H FI LPD
Sbjct: 1117 KYNLKSLRRHIAVVPQEPCLFATTIYENIAYG-HESATEAEITEAATLANAHKFISALPD 1175
Query: 3445 GYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQ 3624
GY T VGE+G QLSGGQKQRIAIARA +R ++LLDEATSALD ESE+ VQEALD A
Sbjct: 1176 GYKTFVGERGVQLSGGQKQRIAIARAFLRKAELMLLDEATSALDAESERCVQEALDRACA 1235
Query: 3625 GRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIR--KSEIYQKFCETQRIVESQ 3795
G+T +V+AHRLSTI+N+ VIA++ +GK+ E+G+H L++ IY + + QR +
Sbjct: 1236 GKTTIVVAHRLSTIRNAHVIAVIDDGKVAEQGSHSHLLKNYSDGIYARMIQLQRFTHGE 1294
>gi|17550138|ref|NP_509810.1| P-GlycoProtein related (pgp-5)
[Caenorhabditis elegans]
gi|7495402|pir||T18939 hypothetical protein C05A9.1 - Caenorhabditis
elegans
gi|3874030|emb|CAA94202.1| Hypothetical protein C05A9.1
[Caenorhabditis elegans]
Length = 1283
Score = 751 bits (1940), Expect = 0.0
Identities = 438/1229 (35%), Positives = 685/1229 (55%), Gaps = 9/1229 (0%)
Frame = +1
Query: 124 TQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPI 303
T + LL G V +++ G P + LG + V ++ N+ +N + + P+
Sbjct: 60 TTRYEKLLFFLGVVFSILTGMCQPFESYTLGETSQVLVKVTNA--------INNKTIDPV 111
Query: 304 SLDE----FNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
L F S++ + + + ++G F ++Q + + + + +R+ Y+ +LR+
Sbjct: 112 DLAHAYKLFESDMNRVVLLFFLVGFAYFTFGFLQFSIMKFVGDNTAYNVRRQYISRLLRK 171
Query: 472 QIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVM 651
I +FD TG+L+ L D++ER RE +K AL++ + F+ G + F+ W +
Sbjct: 172 DISYFDGMSTGHLSIVLNDNMERFREVFNEKIALIIALLTDFVIGTILAFYTDWRLACYG 231
Query: 652 MGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFY 831
F+ IVLSG S + E + AG+IA + +TV SLNG ++E++R+
Sbjct: 232 TVFSFGIVLSGLLDSWGKMKNNEKQNEHISNAGSIAFQALGCYKTVSSLNGQQQEVERYT 291
Query: 832 NALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFA 1011
L+ G + + + + + + ++G+ +I + T + G++ + +
Sbjct: 292 EELKNGEKYALNRAFVFSLSRSADYFFTNALNFVILYFGANMIY-EGTIEPGVVVRILYY 350
Query: 1012 VLSGSTSLGGALPHLASFGTARGAASTVLRVI-NSHPKIDPYSLEGILVDNMKGDISFKD 1188
+L GS LG A+ H++ +A + ++ +S D + E I D +G ISFK+
Sbjct: 351 ILFGSYCLGEAILHISRLASAIPLTVPIADILLDSDATADEFFSEEIK-DTFQGIISFKN 409
Query: 1189 VHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGV 1368
V F YP+R D+ VLK IS ++ G+ IALVG+SG GKST++ LL +Y+ GR+ IDG
Sbjct: 410 VLFSYPTRPDVPVLKEISFNVQGGECIALVGASGSGKSTVIQLLLHYYNIDSGRISIDGN 469
Query: 1369 DLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRL 1548
D+ +N+ LR+ +G+V QEPVLF+ +I ENI+ G AT ++++A K ANA DF+
Sbjct: 470 DIYNINIKQLRQAMGVVFQEPVLFNTSIEENIRFGKPDATEQEIIDALKNANAFDFVCNF 529
Query: 1549 PDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQA 1728
PDG T VGE+G QLSGGQKQRIAIAR LV+NP+ILLLDEATSALD E+E VQ AL +A
Sbjct: 530 PDGIKTIVGERGAQLSGGQKQRIAIARTLVRNPRILLLDEATSALDNESEFIVQEALQKA 589
Query: 1729 QAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXX 1908
GRTTI+VAHRLSTIRN ++I V + G IVE G H++L++ G++ ++
Sbjct: 590 SIGRTTIVVAHRLSTIRNANKIIVMEKGEIVEVGDHKQLIAMNGVYNNLVQTQLMSTNYE 649
Query: 1909 EAGKDIEDTISESAHSHL-XXXXXXXXXXXXXXXIHQLAEEVEECKAPPTSMFKIFKFNG 2085
+ ++ E +S+HS + +L E++E A +++ +I K+
Sbjct: 650 KMNENEERVTRQSSHSDFPSNEISHQKIDQEDDYVKKLIAEIKEEGAKKSNICEIIKYCR 709
Query: 2086 DKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANVYFWCGMFVLMGITFF 2265
+ P+ + + + + Y+ D+M + +FW + + T
Sbjct: 710 SEYCILFIAVLGSAIQGIYYPLSSQLMIKSYEAYAFDKDEMLSKSHFWALSILFLAFTRP 769
Query: 2266 VGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRY 2445
+ F G+ E L++KLR +FK+L+ AFYDD H +L R D+ NV
Sbjct: 770 IFIFFQYYFFGKTAEKLSIKLRSMSFKHLMSLPCAFYDDPCHTATRLSNRLNADSSNVTA 829
Query: 2446 -VFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDT 2622
V RL V+ ++V I A+ + F+Y W+ + GY D+
Sbjct: 830 AVDDRLGSVIMTLVAILLAVIMSFFYSWKMSLQVLMFCPLLYLAGYCNDNFVDQAVEEDS 889
Query: 2623 QLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQS 2802
E++ + A +A+E++RTV +LN + + +L++ N+ K A G F+ S
Sbjct: 890 IAFEKSNRAAIEALENVRTVRALNMENRVILLVTSHLQKIRNSYFKRAVIQGTANGFACS 949
Query: 2803 LIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASL 2982
FF+YA +F G+ V ++ + P+D Y V +S G+ +++PD KA AA L
Sbjct: 950 CYFFIYAVSFKFGTWLVLREEILPMDTYLVLMTLSMTASYAGSAVAYLPDHRKAIHAAGL 1009
Query: 2983 LFYLIEHPT--PIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTV 3156
+F+L +P P DS +K G I ++NV F Y R D +L G +L + AG+T+
Sbjct: 1010 IFHLFTYPAIMPYDSSQGKRNIK--NGEIELKNVSFEYAQRSDKMILDGVSLKLPAGRTL 1067
Query: 3157 ALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCT 3336
ALVG SG GKSTI+ LLERFY+ G + ID +N+ ++N+ LRE V +VSQEP LF+C+
Sbjct: 1068 ALVGPSGSGKSTIISLLERFYHAVDGEVKIDEENVVDVNLHHLRESVSLVSQEPVLFNCS 1127
Query: 3337 IGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIA 3516
I EN +G + N + EI +A K+AN +F+ P G DT VGE+G QLSGGQKQRIAIA
Sbjct: 1128 IKENFLFGISHNASQLEIDQALKVANAFSFVSQFPQGLDTLVGERGAQLSGGQKQRIAIA 1187
Query: 3517 RALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVS 3696
RA++R+P VLLLDEATSALD++SEK+VQ ALD A + + +V+AHRLST+ N+D IA++
Sbjct: 1188 RAILRNPKVLLLDEATSALDSDSEKVVQNALDTASERLSTVVVAHRLSTVVNADSIAVLK 1247
Query: 3697 EGKIVEKGTHDELIRKSEIYQKFCETQRI 3783
GK+ E+GTH+EL+RK IY + + Q I
Sbjct: 1248 NGKVAEQGTHEELLRKRSIYWRLVQKQGI 1276
>gi|50507726|emb|CAA94219.3| Hypothetical protein T21E8.2
[Caenorhabditis elegans]
Length = 1263
Score = 750 bits (1937), Expect = 0.0
Identities = 434/1232 (35%), Positives = 677/1232 (54%), Gaps = 8/1232 (0%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
IF T + L + G +++ G P ++ LG V + N+ + ++P
Sbjct: 31 IFKCTSCFEKFLFLIGVFFSLVTGLCQPFVSYTLGETAQVLVTITNA---INNKTIDPAD 87
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
L + +++ + + +Y+ + G F + +Q A + + +++R+ Y+ +LR+
Sbjct: 88 LKK-AYEQYERGMYQVVLYFFLCGCAYFTFASIQHAIMKYVGDNTTYRVRKQYISRLLRK 146
Query: 472 QIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVM 651
++FD TG+L+ L D+LER RE +K AL+ + F+ G + F+ W +
Sbjct: 147 DAEYFDNVSTGHLSTVLNDNLERFREVFNEKIALIFALLTDFVVGTALAFYTDWRLASYG 206
Query: 652 MGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFY 831
+ F+ I SG S + T + YA AG+IA +T + +TV SLNG E++R+
Sbjct: 207 IFFSLGIAFSGFINSAGVMKTTGKQNTHYANAGSIAFQTLGAYKTVCSLNGQNTEIERYT 266
Query: 832 NALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFA 1011
L+ G + GI + I GF+ S + + G+ +I + + + ++ +F
Sbjct: 267 EELKAGEKYGIHRALMYSISRGFTYFFCNSLNTVILYVGANMIYSG-SLEPAVVVRIFHY 325
Query: 1012 VLSGSTSLGGALPHLASFGTARGAASTVLRV-INSHPKIDPYSLEGILVDNMKGDISFKD 1188
++ G+ L ALPH++ A + + + + I I+ + + + G+ISFK+
Sbjct: 326 MMFGAFCLSEALPHISRLAGAISSTAPIAEMLIKEDNVIEKDETDYDVEVEVNGNISFKN 385
Query: 1189 VHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGV 1368
V F YP+R D VLKGIS +++ G+ IALVG+SG GKST+V LL +Y+ G + IDG+
Sbjct: 386 VKFSYPTRPDAQVLKGISFDVQNGECIALVGASGSGKSTVVQLLLHYYNIDSGNIFIDGM 445
Query: 1369 DLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRL 1548
DL ++N+ LR IG+VSQEPVLF+ TI ENI+ GN + + ++ A + ANA DF+
Sbjct: 446 DLNDMNIKRLRRVIGVVSQEPVLFNTTIEENIRFGNPNVSLPEIYGALRKANAYDFVCSF 505
Query: 1549 PDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQA 1728
P G T VGE+G QLSGGQKQRIAIAR LV+NPKILLLDEATSALD E+E+ VQ AL+ A
Sbjct: 506 PKGIKTIVGERGTQLSGGQKQRIAIARTLVRNPKILLLDEATSALDNESEQVVQKALENA 565
Query: 1729 QAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXX 1908
GRTTI+VAHRLSTIRN +I V + G IVE G+H+EL++K+G++ D+
Sbjct: 566 SQGRTTIVVAHRLSTIRNASKIIVMQKGEIVEVGNHDELIAKRGVYNDLVQAQLLESHDD 625
Query: 1909 E------AGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKAPPTSMFKI 2070
A + + +S HS+ + ++ +E+ + A +++ +I
Sbjct: 626 HEELPPLAARQLSQELSP-LHSYAIQRSTSNDAGVHDDDMERILDELSKEGAKKSNLREI 684
Query: 2071 FKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANVYFWCGMFVLM 2250
K + P+ A + + +++ + M + W F+ +
Sbjct: 685 VKQCRPDYCFLFIAVFGSAIQGVSYPILAQLIVRTYEGFAMIGEDMLYYSHLWALSFMFL 744
Query: 2251 GITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDA 2430
+ + + G+ E L+ +LR ++F ++L AFYDD H +L R TD+
Sbjct: 745 AVFRPLTLYCQYYYFGKVSEQLSTRLRIKSFSHMLSLPCAFYDDPNHSATRLSNRLNTDS 804
Query: 2431 PNVRY-VFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGK 2607
NV+ V RL V+ ++V I A+ Y W+ + Y
Sbjct: 805 SNVKAAVDDRLGCVIMTVVAISIAITTASLYCWKMTLEVLIFFPLLYLAEYCYDAATETS 864
Query: 2608 QIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVF 2787
DT E + + A +A+E++RTV +LN +++ E+L++ + K A GA
Sbjct: 865 IQEDTIAFENSNRTAIEALENMRTVRALNLEDKIMSLISEHLQKIHKSYFKRAIIQGAAN 924
Query: 2788 AFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKAR 2967
S S F+Y+ +F G+ ++ + P+D Y + +S M G+ +++PD KA
Sbjct: 925 GLSLSCYLFVYSVSFKFGTYLALRKEVAPMDTYLILETLSMTANMAGSAAAYLPDYKKAV 984
Query: 2968 LAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAG 3147
AA L+F+L +P + S G G I NV F+Y R D +L G L + G
Sbjct: 985 HAAGLIFHLFTYPATMPFSSSDGKKNIEKGEIIGENVQFHYDQRPDRMILNGVNLKVDPG 1044
Query: 3148 KTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLF 3327
KT+ALVG SGCGKSTI+ LLERFY+ G + ID +N+ ++N++ LR + +VSQEPTLF
Sbjct: 1045 KTLALVGPSGCGKSTIISLLERFYHAVDGEVKIDSENVEDINLNHLRSNLALVSQEPTLF 1104
Query: 3328 DCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRI 3507
+C+I EN+ YG R+V E+ +A + AN NF+ P G DT VGE+G QLSGGQKQRI
Sbjct: 1105 NCSIRENLLYGLTRSVPQLELEKALQTANAFNFVFQFPQGLDTIVGERGAQLSGGQKQRI 1164
Query: 3508 AIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIA 3687
AIARA++R+P VLLLDEATSALD++SEK+VQ ALD A + + +V+AHRL T+ N+D IA
Sbjct: 1165 AIARAILRNPKVLLLDEATSALDSDSEKVVQNALDTASERLSTVVVAHRLLTVVNADSIA 1224
Query: 3688 IVSEGKIVEKGTHDELIRKSEIYQKFCETQRI 3783
++ GK+ E+GTH+EL+RK IY + + Q I
Sbjct: 1225 VLKNGKVAEQGTHEELLRKRSIYWRLVQKQGI 1256
>gi|15217809|ref|NP_174122.1| multidrug resistance P-glycoprotein,
putative [Arabidopsis thaliana]
gi|25297457|pir||F86405 probable P-glycoprotein [imported] -
Arabidopsis thaliana
gi|12322986|gb|AAG51476.1| P-glycoprotein, putative [Arabidopsis
thaliana]
Length = 1247
Score = 749 bits (1934), Expect = 0.0
Identities = 447/1243 (35%), Positives = 683/1243 (53%), Gaps = 17/1243 (1%)
Frame = +1
Query: 109 GIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPE 288
G+F VD L+ G + IHG PL + GGM ++
Sbjct: 35 GLFSAADNVDYFLMFLGGLGTCIHGGTLPLFFVFFGGM------------------LDSL 76
Query: 289 GLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILR 468
G + + +S V + +Y + LG++ ++++ +AC+ ER +LR NYLK+IL
Sbjct: 77 GKLSTDPNAISSRVSQNALYLVYLGLVNLVSAWIGVACWMQTGERQTARLRINYLKSILA 136
Query: 469 QQIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTL 645
+ I +FD + + N ++ D V++ +GDK +++ F+AG+ +GF W +TL
Sbjct: 137 KDITFFDTEARDSNFIFHISSDAILVQDAIGDKTGHVLRYLCQFIAGFVIGFLSVWQLTL 196
Query: 646 VMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDR 825
+ +G PLI ++G + M+T + + YA AG +AEE S +RTV++ G ++ +
Sbjct: 197 LTLGVVPLIAIAGGGYAIVMSTISEKSEAAYADAGKVAEEVMSQVRTVYAFVGEEKAVKS 256
Query: 826 FYN----ALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLI 993
+ N AL++ +++G+ K G+GVG + ++ ++AL FWY S L+ + T +
Sbjct: 257 YSNSLKKALKLSKRSGLAK----GLGVGLTYSLLFCAWALLFWYASLLVRHGKT-NGAKA 311
Query: 994 FTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLE-GILVDNMKG 1170
FT V+ +LG A+P L++ R AA+ + ++I ++ LE G + N+ G
Sbjct: 312 FTTILNVIYSGFALGQAVPSLSAISKGRVAAANIFKMIGNNNLESSERLENGTTLQNVVG 371
Query: 1171 DISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGR 1350
I F V F YPSR ++ V + +S + +G A VG SG GKSTI++++QRFY+P G
Sbjct: 372 KIEFCGVSFAYPSRPNM-VFENLSFTIHSGKTFAFVGPSGSGKSTIISMVQRFYEPRSGE 430
Query: 1351 VLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAN 1530
+L+DG D++ + + LREQ+G+VSQEP LF TI NI +G E A DQ++EA K ANA+
Sbjct: 431 ILLDGNDIKNLKLKWLREQMGLVSQEPALFATTIASNILLGKEKANMDQIIEAAKAANAD 490
Query: 1531 DFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQ 1710
FIK LP+GY T+VGE G QLSGGQKQRIAIARA+++NPKILLLDEATSALD E+E+ VQ
Sbjct: 491 SFIKSLPNGYNTQVGEGGTQLSGGQKQRIAIARAVLRNPKILLLDEATSALDAESEKIVQ 550
Query: 1711 GALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXX 1890
ALD RTTI++AHRLSTIRNVD+I V + G + E+GSH EL+S+ G + +
Sbjct: 551 QALDNVMEKRTTIVIAHRLSTIRNVDKIVVLRDGQVRETGSHSELISRGGDYATLV---- 606
Query: 1891 XXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEV-------EECKAP 2049
E +++ + ES S + +E E+ +
Sbjct: 607 -NCQDTEPQENLRSVMYESCRSQAGSYSSRRVFSSRRTSSFREDQEKTEKDSKGEDLISS 665
Query: 2050 PTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQM-QANVYF 2226
+ ++++ K N + + S +F++ A + + P + + V
Sbjct: 666 SSMIWELIKLNAPEWLYALLGSIGAVLAGSQPALFSMGLAYVLTTFYSPFPSLIKREVDK 725
Query: 2227 WCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKL 2406
+FV GI + GE LT ++R F +L +I ++D + TG L
Sbjct: 726 VAIIFVGAGIVTAPIYILQHYFYTLMGERLTSRVRLSLFSAILSNEIGWFDLDENNTGSL 785
Query: 2407 CTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYF 2583
+ A DA VR + RL ++ ++ AL + F+Y W+
Sbjct: 786 TSILAADATLVRSAIADRLSTIVQNLSLTITALALAFFYSWRVAAVVTACFPLLIAASLT 845
Query: 2584 EMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKH 2763
E G T+ A +A +A+ +IRTV + + ++Q + L +P + L
Sbjct: 846 EQLFLKGFGGDYTRAYSRATSLAREAISNIRTVAAFSAEKQISEQFTCELSKPTKSALLR 905
Query: 2764 AHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSF 2943
H G + SQ L F YA + S+ + + D + F + + T +
Sbjct: 906 GHISGFGYGLSQCLAFCSYALGLWYISVLIKRNETNFEDSIKSFMVLLVTAYSVAETLAL 965
Query: 2944 IPDVVKARLAASLLFYLIEHPTPI-DSLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQ 3120
PD+VK A +F ++ T I +S +V I G+I RNV F YPTR + + +
Sbjct: 966 TPDIVKGTQALGSVFRVLHRETEIPPDQPNSRLVTHIKGDIEFRNVSFAYPTRPEIAIFK 1025
Query: 3121 GFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVC 3300
L + AGK++A+VG SG GKST++GL+ RFY+ G + IDG +I+++N+ SLR+++
Sbjct: 1026 NLNLRVSAGKSLAVVGPSGSGKSTVIGLIMRFYDPSNGNLCIDGHDIKSVNLRSLRKKLA 1085
Query: 3301 IVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQ 3480
+V QEP LF +I ENI YG N N + EI+EAAK AN H FI + +GY THVG+KG Q
Sbjct: 1086 LVQQEPALFSTSIHENIKYG-NENASEAEIIEAAKAANAHEFISRMEEGYMTHVGDKGVQ 1144
Query: 3481 LSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLS 3660
LSGGQKQR+AIARA+++ PSVLLLDEATSALDT +EK VQEALD +GRT +++AHRLS
Sbjct: 1145 LSGGQKQRVAIARAVLKDPSVLLLDEATSALDTSAEKQVQEALDKLMKGRTTILVAHRLS 1204
Query: 3661 TIQNSDVIAIVSEGKIVEKGTHDELIRKSE-IYQKFCETQRIV 3786
TI+ +D I ++ +GK+VEKG+H EL+ KS+ Y+K Q V
Sbjct: 1205 TIRKADTIVVLHKGKVVEKGSHRELVSKSDGFYKKLTSLQEAV 1247
>gi|7494503|pir||T30855 multidrug resistance protein 2 - fluke
(Schistosoma mansoni)
gi|425476|gb|AAA66477.1| SMDR2
Length = 1254
Score = 748 bits (1931), Expect = 0.0
Identities = 463/1254 (36%), Positives = 674/1254 (52%), Gaps = 36/1254 (2%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F Y L+I G + A++ G FP +V M +S+ + G+
Sbjct: 34 LFQYASTCHKFLIIIGNICAILLGISFPASILVFRSMINGLFNRSSSNNIYGLLG----- 88
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
+Y ++ +L+F + C E ++R+V +++ Y +A+L +
Sbjct: 89 ------------------WYFLMAILIFVLCMWKCVCVEFASKRIVQQIQLLYYQAVLHK 130
Query: 472 QIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVM 651
+ WFD TG++ LT++L + G+G K + Q + FLAG +GF W + LV
Sbjct: 131 DVLWFDDHPTGDIINNLTENLNSIESGIGTKLSDFNQNMSGFLAGIIIGFIVKWKLALVA 190
Query: 652 MGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFY 831
P +V++ + + E + Y+ A I+ E SSIRTV + G KRE R+
Sbjct: 191 CSTLPFVVIAFSLFGIAFKYFHGKEIKAYSRACTISNEVLSSIRTVIAFGGEKRESLRYQ 250
Query: 832 NALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFA 1011
L GI K G G L ++SS AL FW+G LI D D G + TVF
Sbjct: 251 KELTSAELMGIKKATAFGSVGGCIGLVIFSSAALVFWFGVKLI-RDEDADPGSVITVFIN 309
Query: 1012 VLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDV 1191
+L GS LG ALP++ A A+ + I+ +I+ G ++ + G I+F+ V
Sbjct: 310 ILLGSIFLGNALPNIPYIMGAVTASKDIFATIDHVCEIEKKD-RGKILSDFDGSITFRHV 368
Query: 1192 HFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVD 1371
+F YPSR D+ +L L +K+G IALVGSSG GKST++++LQRFYDPT+G +LI GVD
Sbjct: 369 NFNYPSRPDVTILVNFCLTVKSGQTIALVGSSGSGKSTLIHMLQRFYDPTQGEILIQGVD 428
Query: 1372 LREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLP 1551
LRE+N+H+ R QIG V QEPVLFDGTI ENI +G +AT +++ EA ANA+ FI RLP
Sbjct: 429 LRELNIHNYRNQIGCVQQEPVLFDGTIRENIGLGKLNATDEEIHEAAIKANAHQFIMRLP 488
Query: 1552 DGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQ 1731
GY T VGEKG LSGGQKQRIAIAR L++ PK+LLLDEATSALDT++ER VQGALD+
Sbjct: 489 QGYDTLVGEKGSNLSGGQKQRIAIARVLIRKPKLLLLDEATSALDTQSERIVQGALDKIV 548
Query: 1732 AGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXXE 1911
G T II+AHRLSTI N D I V G I E G H EL+ G++ M E
Sbjct: 549 GGCTVIIIAHRLSTIINADYIIVLDQGCIREMGKHNELLKLNGLYATMYYGQEGIDKEQE 608
Query: 1912 AGKD--IEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKAPPTS--------- 2058
D ++ ++ + HL ++ EC TS
Sbjct: 609 DSTDDEVDHNQNDGSKRHLTNHHPSPFP----------KDDYSECSNVTTSSLHNKTVIW 658
Query: 2059 ---------------MFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSL 2193
+F N ++ + + P F+L+Y+E++ V+ L
Sbjct: 659 LTTNINTKLVELTILVFASLSINRPEMIYIIMGCFCSIISGLLQPAFSLLYSEVYQVFDL 718
Query: 2194 --PADQMQANVYFWCGMFVLMG-ITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQD 2364
D+M + G+ +G I F+G T G E LT +LR F ++L+Q+
Sbjct: 719 RKTPDEMTKKINMVSGIMAGLGFIQLFIG-ATQGYLFGVAAERLTKRLRSNLFDSMLKQE 777
Query: 2365 IAFYDDLRHGTGKLCTRFATDAPNVRYVF-TRLPVVLASIVTICGALGIGFYYGWQXXXX 2541
I ++D + G L +TDA V + +RL ++V + +L IGF Y WQ
Sbjct: 778 IGWFDRSDNRPGALTAFLSTDASKVAQISGSRLSTAFEAVVLVIASLVIGFIYSWQLTLV 837
Query: 2542 XXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTY 2721
+ M+ R K + +++ + +A +++ RTV SL+ +E F+ +
Sbjct: 838 MIPFIPVLLLSSRINMK-RVSK--NEDKIVAKGISIAKESISAHRTVKSLSLEEYFYQRF 894
Query: 2722 CEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFA 2901
E +T+L+ A G V + + S A F LG+ + Q A+ I +++VF
Sbjct: 895 KLACIECSSTHLQEAIKIGLVQSIALSGPVLSLTACFALGNYLIQQNAISMISLFKVFIT 954
Query: 2902 ISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVF 3081
S C Q +G T+F +A A +F +I+ I++ + G I ++V
Sbjct: 955 FSMCSQALGRITAFTTKTKEAEEAMGRIFTVIDRKPSIETNQGDQPKEKFNGLIEFKHVN 1014
Query: 3082 FNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYN-QDKGM---IMID 3249
F YPTR +TKVL FT I+ G +ALVG SGCGKST++ LL+RFY+ D G+ I D
Sbjct: 1015 FRYPTRPETKVLNNFTYRIQPGSKIALVGQSGCGKSTLIQLLQRFYDPTDHGLHNGIFFD 1074
Query: 3250 GDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNF 3426
G N+R L +R Q+ IVSQEP LF+ ++ +NI YG N R V+ EI+EAAK+ANIH+F
Sbjct: 1075 GINLRQLAPYWIRRQIGIVSQEPILFNISLRDNIAYGDNSRIVSMDEIIEAAKLANIHDF 1134
Query: 3427 ILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEA 3606
IL LP+ Y+T G+ G+ LSGGQKQRIAIARA++R P++LLLDEATSALD E++++VQ+A
Sbjct: 1135 ILSLPNAYETLAGQDGSHLSGGQKQRIAIARAIIRKPTLLLLDEATSALDNENQRLVQKA 1194
Query: 3607 LDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELI-RKSEIYQKF 3765
LD A RT ++IAHRL+TI+ D I ++S G+I+E G +ELI RK E + +
Sbjct: 1195 LDDAMVTRTSIIIAHRLNTIEKVDYIIVLSNGRIIEYGKLNELIHRKGEFFNLY 1248
>gi|24659289|ref|NP_648040.1| CG10226-PA [Drosophila melanogaster]
gi|7295352|gb|AAF50670.1| CG10226-PA [Drosophila melanogaster]
Length = 1320
Score = 745 bits (1924), Expect = 0.0
Identities = 451/1279 (35%), Positives = 702/1279 (54%), Gaps = 57/1279 (4%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQ----NSDFVVGVD-- 273
+F Y G D L+L++G VAA + FP+ +V + +F+ S +G+
Sbjct: 41 LFRYIAGWDYLVLLSGFVAAFLQSLVFPIAIVVYSELVAMFIERTLGQGTSSVTIGLSLF 100
Query: 274 ---NVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQ 444
+ ++ E + V + I + +LM F+ + F A +L ++R+
Sbjct: 101 GGGKILTNASYEENMQELRKDSVSFGILMTLNTLLMLFSGVYYVDAFNRLALKLTVRMRR 160
Query: 445 NYLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFF 624
+ KA LRQ+I W D + N R+TD++E++R G+ + V++ + + F
Sbjct: 161 EFFKATLRQEIGWHDMAKDQNFAVRITDNMEKIRSGIAENLGHYVEIMCDVIISVVLSFI 220
Query: 625 YSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNG 804
Y W + L ++ + PL ++ + ++ T EQ +Y A ++ EE +IRTV + G
Sbjct: 221 YGWKLALAIVFYIPLTLVVNSAVAHYQGKLTGQEQSSYVRASSVVEEVIGAIRTVVAFGG 280
Query: 805 HKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLII--NDPT- 975
+ E R+ + L+ + G K + G+ ++ + A +FWYG+ LI+ DP+
Sbjct: 281 ERSESLRYDSLLKPALKAGKWKGAFSGLSDTVMKAMLFITGAGSFWYGANLILYYRDPSI 340
Query: 976 ------FDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYS 1137
+ ++ V ++ + + P L +F ARG+AS +L VI+ IDP S
Sbjct: 341 PIDEREYTPAVVMIVISGIIVSANQISRTSPFLETFAMARGSASAILDVIDRTSLIDPLS 400
Query: 1138 LEG-ILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVN 1314
G IL +KG + F+DV FRYP+R+D+ VL+G+++ ++ G +ALVG SGCGKST +
Sbjct: 401 KAGKILNYGLKGAVEFRDVFFRYPAREDVIVLRGLNVVVEEGQTVALVGPSGCGKSTCIQ 460
Query: 1315 LLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHD 1494
LLQRFYDP G+VL+DG D+R+ N+ LR I +V QEPVLF G+I ENI+ G AT
Sbjct: 461 LLQRFYDPVFGQVLLDGEDVRKYNIKWLRSNIAVVGQEPVLFQGSIGENIRHGKPEATQK 520
Query: 1495 QVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEAT 1674
+V +A K ANA+DFI L GY T + EKGVQLSGGQ+QRIAIARAL++ PKILLLDEAT
Sbjct: 521 EVEDAAKAANAHDFIIALHKGYDTDISEKGVQLSGGQRQRIAIARALIQQPKILLLDEAT 580
Query: 1675 SALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSK 1854
SALD +E+ VQ ALD+A GRTT++V+HRLS IR+ RI + G VE G+HEELM
Sbjct: 581 SALDYHSEKLVQAALDKACKGRTTLVVSHRLSAIRHAHRIVYIENGKAVEQGTHEELMKL 640
Query: 1855 QGIFYDMTXXXXXXXXXXEAGKDIEDT--ISESAHSH---------------LXXXXXXX 1983
+G ++ M E ++E+ I E S+ L
Sbjct: 641 EGFYHKMVTVHSYDDSAEELLNELEEVAEIKERKMSYEVEPYQLGTRNSIVSLEKNAEFQ 700
Query: 1984 XXXXXXXXIHQLAEEVEECKAPP----TSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPV 2151
+ +E+++ + P ++ F+I + + + PV
Sbjct: 701 MKNLNGLANITMNQEIDDPRVPSANFISTFFRILGWARPEWSFLIIGAICAGLYGVTMPV 760
Query: 2152 FALVYAEIFNVYSLPAD-QMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKL 2328
F++V AE++ + P D ++ + +++GI V + G LT ++
Sbjct: 761 FSVVLAELYGSLAKPTDEEVLEQSASMAIISLVIGIAAGVVCYIQTFFFNLAGVWLTTRM 820
Query: 2329 RFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYV--FTRLPVVLASIVTICGAL 2502
R + F+ ++ Q++ ++D + G L R + DA +V+ F ++ A IC ++
Sbjct: 821 RSKTFRCIMNQEMGWFDRKENSIGALSARLSGDAASVQGAIGFPLSNIIQAFTNFIC-SI 879
Query: 2503 GIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTV 2682
I F Y W+ FE + +++ ++LEE ++A++ + IRTV
Sbjct: 880 AIAFPYSWELALICLSTSPFMVASIVFEARFGEKSALKEKEVLEETSRIATETITQIRTV 939
Query: 2683 HSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQ 2862
L R+E+ Y + + + L G V + +SL+FF YA G
Sbjct: 940 AGLRREEELIKIYDKEVERYRHQILSRLKWRGLVNSLGKSLMFFGYAVTLTYGGHMCADG 999
Query: 2863 AMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIV 3042
++ + ++ + + ++ + +F P A L+A+ ++ +I+ I S I
Sbjct: 1000 KIKFETIMKISNTMLYGLFILAQSLAFTPAFNAALLSANRMYEIIDRKPQIQSPESFEIQ 1059
Query: 3043 KPITG----------NISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKST 3192
+ G +S R + F+YP+R KVLQ F LDI G+TVALVG SG GKST
Sbjct: 1060 QNGNGTAYKTNVVQQGVSYRGLNFSYPSRPHIKVLQNFNLDINQGQTVALVGASGSGKST 1119
Query: 3193 IMGLLERFYNQDKGMIMIDGDNI-RNLNISSLREQVCIVSQEPTLFDCTIGENICYG-TN 3366
+ LL R+Y+ D+G I+ID ++I ++++ +LR ++ IVSQEP+LF+ +I +NI YG T+
Sbjct: 1120 CVQLLMRYYDPDEGKILIDQESIHHDMDLKTLRRRLGIVSQEPSLFEKSIADNIGYGDTS 1179
Query: 3367 RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVL 3546
R V Q+I+EAAKMAN H FI+ LP YDT +G KGTQLSGGQKQRIAIARA+VR+P +L
Sbjct: 1180 RQVPMQQIIEAAKMANAHEFIMSLPAQYDTVLGSKGTQLSGGQKQRIAIARAMVRNPKIL 1239
Query: 3547 LLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTH 3726
LLDEATSALD +SE++VQ+ALD+A GRTC+VIAHRLSTIQN++VI ++ GKIVE+G+H
Sbjct: 1240 LLDEATSALDFQSERVVQQALDSACSGRTCIVIAHRLSTIQNANVICVIQAGKIVEQGSH 1299
Query: 3727 DELIRKSEIYQKF--CETQ 3777
+L+ K+ IY K C+T+
Sbjct: 1300 SQLLAKNGIYSKLYRCQTK 1318
>gi|17569909|ref|NP_509812.1| P-GlycoProtein related (pgp-7)
[Caenorhabditis elegans]
Length = 1269
Score = 744 bits (1922), Expect = 0.0
Identities = 434/1238 (35%), Positives = 678/1238 (54%), Gaps = 14/1238 (1%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
IF T + L + G +++ G P ++ LG V + N+ + ++P
Sbjct: 31 IFKCTSCFEKFLFLIGVFFSLVTGLCQPFVSYTLGETAQVLVTITNA---INNKTIDPAD 87
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
L + +++ + + +Y+ + G F + +Q A + + +++R+ Y+ +LR+
Sbjct: 88 LKK-AYEQYERGMYQVVLYFFLCGCAYFTFASIQHAIMKYVGDNTTYRVRKQYISRLLRK 146
Query: 472 QIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVM 651
++FD TG+L+ L D+LER RE +K AL+ + F+ G + F+ W +
Sbjct: 147 DAEYFDNVSTGHLSTVLNDNLERFREVFNEKIALIFALLTDFVVGTALAFYTDWRLASYG 206
Query: 652 MGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFY 831
+ F+ I SG S + T + YA AG+IA +T + +TV SLNG E++R+
Sbjct: 207 IFFSLGIAFSGFINSAGVMKTTGKQNTHYANAGSIAFQTLGAYKTVCSLNGQNTEIERYT 266
Query: 832 NALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFA 1011
L+ G + GI + I GF+ S + + G+ +I + + + ++ +F
Sbjct: 267 EELKAGEKYGIHRALMYSISRGFTYFFCNSLNTVILYVGANMIYSG-SLEPAVVVRIFHY 325
Query: 1012 VLSGSTSLGGALPHLASFGTARGAASTVLRV-INSHPKIDPYSLEGILVDNMKGDISFKD 1188
++ G+ L ALPH++ A + + + + I I+ + + + G+ISFK+
Sbjct: 326 MMFGAFCLSEALPHISRLAGAISSTAPIAEMLIKEDNVIEKDETDYDVEVEVNGNISFKN 385
Query: 1189 VHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGV 1368
V F YP+R D VLKGIS +++ G+ IALVG+SG GKST+V LL +Y+ G + IDG+
Sbjct: 386 VKFSYPTRPDAQVLKGISFDVQNGECIALVGASGSGKSTVVQLLLHYYNIDSGNIFIDGM 445
Query: 1369 DLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRL 1548
DL ++N+ LR IG+VSQEPVLF+ TI ENI+ GN + + ++ A + ANA DF+
Sbjct: 446 DLNDMNIKRLRRVIGVVSQEPVLFNTTIEENIRFGNPNVSLPEIYGALRKANAYDFVCSF 505
Query: 1549 PDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQA 1728
P G T VGE+G QLSGGQKQRIAIAR LV+NPKILLLDEATSALD E+E+ VQ AL+ A
Sbjct: 506 PKGIKTIVGERGTQLSGGQKQRIAIARTLVRNPKILLLDEATSALDNESEQVVQKALENA 565
Query: 1729 QAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXX 1908
GRTTI+VAHRLSTIRN +I V + G IVE G+H+EL++K+G++ D+
Sbjct: 566 SQGRTTIVVAHRLSTIRNASKIIVMQKGEIVEVGNHDELIAKRGVYNDLVQAQLLESHDD 625
Query: 1909 E------AGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKAPPTSMFKI 2070
A + + +S HS+ + ++ +E+ + A +++ +I
Sbjct: 626 HEELPPLAARQLSQELS-PLHSYAIQRSTSNDAGVHDDDMERILDELSKEGAKKSNLREI 684
Query: 2071 FKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANVYFWCGMFVLM 2250
K + P+ A + + +++ + M + W F+ +
Sbjct: 685 VKQCRPDYCFLFIAVFGSAIQGVSYPILAQLIVRTYEGFAMIGEDMLYYSHLWALSFMFL 744
Query: 2251 GITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDA 2430
+ + + G+ E L+ +LR ++F ++L AFYDD H +L R TD+
Sbjct: 745 AVFRPLTLYCQYYYFGKVSEQLSTRLRIKSFSHMLSLPCAFYDDPNHSATRLSNRLNTDS 804
Query: 2431 PNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGK 2607
NV+ V RL V+ ++V I A+ Y W+ + Y
Sbjct: 805 SNVKAAVDDRLGCVIMTVVAISIAITTASLYCWKMTLEVLIFFPLLYLAEYCYDAATETS 864
Query: 2608 QIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVF 2787
DT E + + A +A+E++RTV +LN +++ E+L++ + K A GA
Sbjct: 865 IQEDTIAFENSNRTAIEALENMRTVRALNLEDKIMSLISEHLQKIHKSYFKRAIIQGAAN 924
Query: 2788 AFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKAR 2967
S S F+Y+ +F G+ ++ + P+D Y + +S M G+ +++PD KA
Sbjct: 925 GLSLSCYLFVYSVSFKFGTYLALRKEVAPMDTYLILETLSMTANMAGSAAAYLPDYKKAV 984
Query: 2968 LAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAG 3147
AA L+F+L +P + S G G I NV F+Y R D +L G L + G
Sbjct: 985 HAAGLIFHLFTYPATMPFSSSDGKKNIEKGEIIGENVQFHYDQRPDRMILNGVNLKVDPG 1044
Query: 3148 KTVALVGHSGCGKSTIMGLLERFYNQDKGMIM------IDGDNIRNLNISSLREQVCIVS 3309
KT+ALVG SGCGKSTI+ LLERFY+ G ++ ID +N+ ++N++ LR + +VS
Sbjct: 1045 KTLALVGPSGCGKSTIISLLERFYHAVDGEVVSIDAHKIDSENVEDINLNHLRSNLALVS 1104
Query: 3310 QEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSG 3489
QEPTLF+C+I EN+ YG R+V E+ +A + AN NF+ P G DT VGE+G QLSG
Sbjct: 1105 QEPTLFNCSIRENLLYGLTRSVPQLELEKALQTANAFNFVFQFPQGLDTIVGERGAQLSG 1164
Query: 3490 GQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQ 3669
GQKQRIAIARA++R+P VLLLDEATSALD++SEK+VQ ALD A + + +V+AHRL T+
Sbjct: 1165 GQKQRIAIARAILRNPKVLLLDEATSALDSDSEKVVQNALDTASERLSTVVVAHRLLTVV 1224
Query: 3670 NSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRI 3783
N+D IA++ GK+ E+GTH+EL+RK IY + + Q I
Sbjct: 1225 NADSIAVLKNGKVAEQGTHEELLRKRSIYWRLVQKQGI 1262
>gi|27368861|emb|CAD59588.1| MDR-like ABC transporter [Oryza sativa
(japonica cultivar-group)]
Length = 1159
Score = 742 bits (1915), Expect = 0.0
Identities = 435/1178 (36%), Positives = 647/1178 (53%), Gaps = 37/1178 (3%)
Frame = +1
Query: 349 YLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQ-TGNLTARLT 525
++ LGV S +Q++C+ ER ++R YLKAILRQ I +FDK+ TG L R++
Sbjct: 3 FIYLGVGAGLVSALQVSCWTITGERQAARIRALYLKAILRQDIAFFDKEMNTGQLVERMS 62
Query: 526 DDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSM 705
D +++ +G+K +Q+ + F G+ + F W + LVM+ P + ++GA MS+ M
Sbjct: 63 GDAFLIQDAIGEKAGKCIQLLSTFFGGFIIAFVRGWLLALVMLSSIPPVAVAGAIMSRLM 122
Query: 706 ATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMG 885
T Q Y AG + E+T +IRTV + NG K+ ++ + ++ ++ + + G
Sbjct: 123 VKLTIRMQAKYGDAGIVVEQTIGAIRTVVAFNGEKKAINTYNKFIKKAYESALQQGVING 182
Query: 886 IGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASF 1065
+G+G +SSY LA WYGS LI+ + ++ G++ V A++ + SLG A + +
Sbjct: 183 LGLGSIISVFFSSYGLAVWYGSRLIV-ERGYNGGIVINVIMAIMISAMSLGHATSSITAL 241
Query: 1066 GTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISL 1245
+GAA + R I P ID G + +++KGD+ K+V+F YPSR + V G SL
Sbjct: 242 AGGQGAAYRLFRTIERQPDIDACCTTGDIFEDVKGDVELKNVYFSYPSRPEHLVFDGFSL 301
Query: 1246 ELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQ 1425
++ +G ++ALVG SG GKST+++L++RFYDP G VLIDGVD+R +N+ S+R +IG+VSQ
Sbjct: 302 QVPSGTRMALVGESGSGKSTVISLVERFYDPQSGEVLIDGVDIRRINLGSIRRKIGLVSQ 361
Query: 1426 EPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQ 1605
EPVLF GTI ENI G E T +++ A ++ANA FI +LP+G T VGE+G+QLSGGQ
Sbjct: 362 EPVLFAGTIRENITYGKEDPTLEEINRAIELANAAKFIDKLPNGLETMVGERGIQLSGGQ 421
Query: 1606 KQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNV 1785
KQRIAIAR ++KNP+ILLLDEATSALD E+ER VQ AL++ RTTIIVAHRLST++N
Sbjct: 422 KQRIAIARVIIKNPRILLLDEATSALDMESERVVQEALNKVMLERTTIIVAHRLSTVKNA 481
Query: 1786 DRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXXEAGKDIEDTI--------- 1938
D I V + G +VE GSHEELM K Y A D D I
Sbjct: 482 DMISVLQHGKLVEQGSHEELMKKPEGSYCKLIHLQETRQEAVAPNDDPDMIIRNDFDSRI 541
Query: 1939 --SESAHSHLXXXXXXXXXXXXXXX----------------------IHQLAEEVEECKA 2046
S++ ++ I + +++ C+
Sbjct: 542 INSKTRSQNISFRKSTSKSSSFGHSGTHPFTSTCDLSDPMEVHDDQHIKETTDKMSNCQ- 600
Query: 2047 PPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANVYF 2226
S+ ++F N + + PVF ++ + ++ P ++ N
Sbjct: 601 EKASILRLFSLNKPEAFVLALGSITAAMHGVIFPVFGILVSSAIKMFYEPRSELLKNSRL 660
Query: 2227 WCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKL 2406
MF ++GI+ F+ T G G L ++R FK+++ Q+I+++D + +G +
Sbjct: 661 LGSMFPVLGISTFLLIPTEYFLFGLAGGKLVERIRSLTFKSVMYQEISWFDKPENSSGSI 720
Query: 2407 CTRFATDAPNV-RYVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYF 2583
R +TDA NV R V L + ++ TI I W+ Y
Sbjct: 721 GARLSTDALNVKRLVGDNLALNFQTLSTIISGFTIAMVANWKLALIITVVVPLVGFQAYA 780
Query: 2584 EMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKH 2763
+M G + E+A +VA++AV IRT+ S +++ Y + P ++
Sbjct: 781 QMMFLKGFNKNAKSMFEDATQVATEAVGGIRTITSFCAEQKVMNAYEKKCASPIIQGIRD 840
Query: 2764 AHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSF 2943
F FS + +F YA FY+G+ FV+Q +V+RVFF + I T++
Sbjct: 841 GVVGALGFGFSFLVFYFAYALCFYVGAKFVHQGTATFAEVFRVFFVLVLGINEISRTSAI 900
Query: 2944 IPDVVKARLAASLLFYLIEHPTPIDSLSDSGIV-KPITGNISIRNVFFNYPTRKDTKVLQ 3120
+ + + +F +++ + IDS +D G+V + G+I +N
Sbjct: 901 GSESRRVNESVVSVFKILDRKSKIDSSNDEGVVIASVRGDIEFQN--------------- 945
Query: 3121 GFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVC 3300
T ALVG SG GKST++ LLERFY D G I+ DG + L +S LR Q+
Sbjct: 946 ----------TAALVGESGSGKSTVISLLERFYEPDAGRILFDGVELETLKVSWLRLQIG 995
Query: 3301 IVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQ 3480
+V+QEP LF+ TI NI YG + + +EI+ AA+ AN H FI GLPDGY+T VGE+G Q
Sbjct: 996 LVAQEPVLFNDTIRANIAYGKQGDASEEEIIAAAEAANAHQFISGLPDGYNTIVGERGIQ 1055
Query: 3481 LSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLS 3660
LSGGQKQR+AIARA+++ P VLLLDEATSALD+ESE++VQEALD GRT +V+AHRLS
Sbjct: 1056 LSGGQKQRVAIARAVIKDPKVLLLDEATSALDSESERVVQEALDREVVGRTTVVVAHRLS 1115
Query: 3661 TIQNSDVIAIVSEGKIVEKGTHDELIR-KSEIYQKFCE 3771
TI+ +D+I ++ G IVEKG H+EL++ K IY E
Sbjct: 1116 TIKGADIIGVLENGTIVEKGRHEELMQIKGGIYSSLVE 1153
Score = 329 bits (844), Expect = 3e-88
Identities = 201/585 (34%), Positives = 310/585 (52%), Gaps = 7/585 (1%)
Frame = +1
Query: 136 DLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDE 315
+ +L G++ A +HG FP+ I++ +F E
Sbjct: 615 EAFVLALGSITAAMHGVIFPVFGILVSSAIKMFY-------------------------E 649
Query: 316 FNSEVVKYC----IYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQW 483
SE++K + VLG+ F + F +LV ++R K+++ Q+I W
Sbjct: 650 PRSELLKNSRLLGSMFPVLGISTFLLIPTEYFLFGLAGGKLVERIRSLTFKSVMYQEISW 709
Query: 484 FDKQQ--TGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMG 657
FDK + +G++ ARL+ D V+ +GD AL Q + ++G+ + +W + L++
Sbjct: 710 FDKPENSSGSIGARLSTDALNVKRLVGDNLALNFQTLSTIISGFTIAMVANWKLALIITV 769
Query: 658 FAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNA 837
PL+ + + + + A +A E IRT+ S ++ ++ +
Sbjct: 770 VVPLVGFQAYAQMMFLKGFNKNAKSMFEDATQVATEAVGGIRTITSFCAEQKVMNAYEKK 829
Query: 838 LEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVL 1017
GI +G GFS L Y +YAL F+ G+ ++ T +F VFF ++
Sbjct: 830 CASPIIQGIRDGVVGALGFGFSFLVFYFAYALCFYVGAK-FVHQGTATFAEVFRVFFVLV 888
Query: 1018 SGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHF 1197
G + + + +V ++++ KID + EG+++ +++GDI F++
Sbjct: 889 LGINEISRTSAIGSESRRVNESVVSVFKILDRKSKIDSSNDEGVVIASVRGDIEFQNT-- 946
Query: 1198 RYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLR 1377
ALVG SG GKST+++LL+RFY+P GR+L DGV+L
Sbjct: 947 -----------------------AALVGESGSGKSTVISLLERFYEPDAGRILFDGVELE 983
Query: 1378 EVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNE-HATHDQVVEACKMANANDFIKRLPD 1554
+ V LR QIG+V+QEPVLF+ TI NI G + A+ ++++ A + ANA+ FI LPD
Sbjct: 984 TLKVSWLRLQIGLVAQEPVLFNDTIRANIAYGKQGDASEEEIIAAAEAANAHQFISGLPD 1043
Query: 1555 GYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQA 1734
GY T VGE+G+QLSGGQKQR+AIARA++K+PK+LLLDEATSALD+E+ER VQ ALD+
Sbjct: 1044 GYNTIVGERGIQLSGGQKQRVAIARAVIKDPKVLLLDEATSALDSESERVVQEALDREVV 1103
Query: 1735 GRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFY 1869
GRTT++VAHRLSTI+ D I V + G IVE G HEELM +G Y
Sbjct: 1104 GRTTVVVAHRLSTIKGADIIGVLENGTIVEKGRHEELMQIKGGIY 1148
Score = 322 bits (824), Expect = 6e-86
Identities = 190/521 (36%), Positives = 298/521 (56%), Gaps = 2/521 (0%)
Frame = +1
Query: 2239 FVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRF 2418
F+ +G+ + +C GE ++R K +LRQDIAF+D TG+L R
Sbjct: 3 FIYLGVGAGLVSALQVSCWTITGERQAARIRALYLKAILRQDIAFFDK-EMNTGQLVERM 61
Query: 2419 ATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQM 2595
+ DA ++ + + + + T G I F GW + G ++
Sbjct: 62 SGDAFLIQDAIGEKAGKCIQLLSTFFGGFIIAFVRGWLLALVMLSSIPPVAVAGAIMSRL 121
Query: 2596 RFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTY 2775
IR +AG V Q + IRTV + N +++ TY +++++ + + L+
Sbjct: 122 MVKLTIRMQAKYGDAGIVVEQTIGAIRTVVAFNGEKKAINTYNKFIKKAYESALQQGVIN 181
Query: 2776 GAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDV 2955
G S+ F Y A + GS + ++ V V AI +G+ TS I +
Sbjct: 182 GLGLGSIISVFFSSYGLAVWYGSRLIVERGYNGGIVINVIMAIMISAMSLGHATSSITAL 241
Query: 2956 VKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTKVLQGFTL 3132
+ AA LF IE ID+ +G I + + G++ ++NV+F+YP+R + V GF+L
Sbjct: 242 AGGQGAAYRLFRTIERQPDIDACCTTGDIFEDVKGDVELKNVYFSYPSRPEHLVFDGFSL 301
Query: 3133 DIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQ 3312
+ +G +ALVG SG GKST++ L+ERFY+ G ++IDG +IR +N+ S+R ++ +VSQ
Sbjct: 302 QVPSGTRMALVGESGSGKSTVISLVERFYDPQSGEVLIDGVDIRRINLGSIRRKIGLVSQ 361
Query: 3313 EPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGG 3492
EP LF TI ENI YG + T +EI A ++AN FI LP+G +T VGE+G QLSGG
Sbjct: 362 EPVLFAGTIRENITYG-KEDPTLEEINRAIELANAAKFIDKLPNGLETMVGERGIQLSGG 420
Query: 3493 QKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQN 3672
QKQRIAIAR ++++P +LLLDEATSALD ESE++VQEAL+ RT +++AHRLST++N
Sbjct: 421 QKQRIAIARVIIKNPRILLLDEATSALDMESERVVQEALNKVMLERTTIIVAHRLSTVKN 480
Query: 3673 SDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRIVESQ 3795
+D+I+++ GK+VE+G+H+EL++K E +C+ + E++
Sbjct: 481 ADMISVLQHGKLVEQGSHEELMKKPE--GSYCKLIHLQETR 519
>gi|15228052|ref|NP_181228.1| multidrug resistance P-glycoprotein
(PGP1) [Arabidopsis thaliana]
gi|419760|pir||A42150 P-glycoprotein pgp1 - Arabidopsis thaliana
gi|3849833|emb|CAA43646.1| P-glycoprotein [Arabidopsis thaliana]
gi|4883607|gb|AAD31576.1| putative ABC transporter [Arabidopsis
thaliana]
Length = 1286
Score = 742 bits (1915), Expect = 0.0
Identities = 441/1259 (35%), Positives = 682/1259 (54%), Gaps = 31/1259 (2%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F + G+D +L+ G+V A +HG PL FLR D VN G
Sbjct: 32 LFRFADGLDYVLMGIGSVGAFVHGCSLPL-----------FLR-------FFADLVNSFG 73
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
++++ EV+KY +Y+LV+G ++ +S+ +I+C+ ER K+R YL+A L Q
Sbjct: 74 SNSNNVEKMMEEVLKYALYFLVVGAAIWASSWAEISCWMWSGERQTTKMRIKYLEAALNQ 133
Query: 472 QIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLV 648
IQ+FD + +T ++ + D V++ + +K + A F++G+ VGF W + LV
Sbjct: 134 DIQFFDTEVRTSDVVFAINTDAVMVQDAISEKLGNFIHYMATFVSGFIVGFTAVWQLALV 193
Query: 649 MMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRF 828
+ PLI + G + +++ + QE+ + AG I E+T IR V + G R +
Sbjct: 194 TLAVVPLIAVIGGIHTTTLSKLSNKSQESLSQAGNIVEQTVVQIRVVMAFVGESRASQAY 253
Query: 829 YNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFF 1008
+AL++ ++ G G+G+G + ++ YAL WYG L+ + T + GL F
Sbjct: 254 SSALKIAQKLGYKTGLAKGMGLGATYFVVFCCYALLLWYGGYLVRHHLT-NGGLAIATMF 312
Query: 1009 AVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKD 1188
AV+ G +LG + P +A+F A+ AA+ + R+I+ P I+ S G+ +D++ G + K+
Sbjct: 313 AVMIGGLALGQSAPSMAAFAKAKVAAAKIFRIIDHKPTIERNSESGVELDSVTGLVELKN 372
Query: 1189 VHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGV 1368
V F YPSR D+ +L L + AG IALVGSSG GKST+V+L++RFYDP G+VL+DG
Sbjct: 373 VDFSYPSRPDVKILNNFCLSVPAGKTIALVGSSGSGKSTVVSLIERFYDPNSGQVLLDGQ 432
Query: 1369 DLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRL 1548
DL+ + + LR+QIG+VSQEP LF +I ENI +G A ++ EA ++ANA+ FI +L
Sbjct: 433 DLKTLKLRWLRQQIGLVSQEPALFATSIKENILLGRPDADQVEIEEAARVANAHSFIIKL 492
Query: 1549 PDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQA 1728
PDG+ T+VGE+G+QLSGGQKQRIAIARA++KNP ILLLDEATSALD+E+E+ VQ ALD+
Sbjct: 493 PDGFDTQVGERGLQLSGGQKQRIAIARAMLKNPAILLLDEATSALDSESEKLVQEALDRF 552
Query: 1729 QAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSK--QGIFYD---------- 1872
GRTT+I+AHRLSTIR D + V + G++ E G+H+EL SK G++
Sbjct: 553 MIGRTTLIIAHRLSTIRKADLVAVLQQGSVSEIGTHDELFSKGENGVYAKLIKMQEAAHE 612
Query: 1873 --MTXXXXXXXXXXEAGKDIEDTISESAHSH---------LXXXXXXXXXXXXXXXIHQL 2019
M+ A + I S+
Sbjct: 613 TAMSNARKSSARPSSARNSVSSPIMTRNSSYGRSPYSRRLSDFSTSDFSLSIDASSYPNY 672
Query: 2020 AEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLP- 2196
E K S +++ K N + + S++ FA V + + +VY P
Sbjct: 673 RNEKLAFKDQANSFWRLAKMNSPEWKYALLGSVGSVICGSLSAFFAYVLSAVLSVYYNPD 732
Query: 2197 ADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFY 2376
+ M + +C + + + V + GE+LT ++R + +L+ ++A++
Sbjct: 733 HEYMIKQIDKYCYLLIGLSSAALVFNTLQHSFWDIVGENLTKRVREKMLSAVLKNEMAWF 792
Query: 2377 DDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXX 2553
D + + ++ R A DA NVR + R+ V++ + + A GF W+
Sbjct: 793 DQEENESARIAARLALDANNVRSAIGDRISVIVQNTALMLVACTAGFVLQWRLALVLVAV 852
Query: 2554 XXXXXMGGYFEMQMRFGKQIRDTQLLEEAG-KVASQAVEHIRTVHSLNRQEQFHFTYCEY 2730
+ G D + G ++A +A+ ++RTV + N + + Y
Sbjct: 853 FPVVVAATVLQKMFMTGFS-GDLEAAHAKGTQLAGEAIANVRTVAAFNSEAKIVRLYTAN 911
Query: 2731 LREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISF 2910
L P G+ + +Q ++ YA + S V RVF +
Sbjct: 912 LEPPLKRCFWKGQIAGSGYGVAQFCLYASYALGLWYASWLVKHGISDFSKTIRVFMVLMV 971
Query: 2911 CGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPI--DSLSDSGIVKPITGNISIRNVFF 3084
T + PD +K A +F L++ T I D + + + G + ++++ F
Sbjct: 972 SANGAAETLTLAPDFIKGGQAMRSVFELLDRKTEIEPDDPDTTPVPDRLRGEVELKHIDF 1031
Query: 3085 NYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIR 3264
+YP+R D ++ + +L +AGKT+ALVG SGCGKS+++ L++RFY G +MIDG +IR
Sbjct: 1032 SYPSRPDIQIFRDLSLRARAGKTLALVGPSGCGKSSVISLIQRFYEPSSGRVMIDGKDIR 1091
Query: 3265 NLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPD 3444
N+ ++R+ + IV QEP LF TI ENI YG + T EI++AA +A+ H FI LP+
Sbjct: 1092 KYNLKAIRKHIAIVPQEPCLFGTTIYENIAYG-HECATEAEIIQAATLASAHKFISALPE 1150
Query: 3445 GYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQ 3624
GY T+VGE+G QLSGGQKQRIAIARALVR ++LLDEATSALD ESE+ VQEALD A
Sbjct: 1151 GYKTYVGERGVQLSGGQKQRIAIARALVRKAEIMLLDEATSALDAESERSVQEALDQACS 1210
Query: 3625 GRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRK--SEIYQKFCETQRIVESQ 3795
GRT +V+AHRLSTI+N+ VIA++ +GK+ E+G+H L++ IY + + QR +Q
Sbjct: 1211 GRTSIVVAHRLSTIRNAHVIAVIDDGKVAEQGSHSHLLKNHPDGIYARMIQLQRFTHTQ 1269
>gi|27368851|emb|CAD59583.1| MDR-like ABC transporter [Oryza sativa
(japonica cultivar-group)]
gi|41052997|dbj|BAD07906.1| MDR-like ABC transporter [Oryza sativa
(japonica cultivar-group)]
gi|41053280|dbj|BAD07706.1| MDR-like ABC transporter [Oryza sativa
(japonica cultivar-group)]
Length = 1264
Score = 741 bits (1912), Expect = 0.0
Identities = 448/1248 (35%), Positives = 686/1248 (54%), Gaps = 20/1248 (1%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F + D +L+ G++ A HGA P+ I G + +N G
Sbjct: 40 LFSFADRWDYVLMAVGSLGACAHGASVPVFFIFFGKL------------------INIIG 81
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
L + + V KY + ++ LG+++ F+S+ ++AC+ ER K+RQ YL+++L Q
Sbjct: 82 LAYLFPTTVSGRVAKYSLDFVYLGIVILFSSWTEVACWMHTGERQAAKMRQAYLRSMLDQ 141
Query: 472 QIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLV 648
I FD + TG + +T D+ V++ + +K + + FLAG+ +GF W ++LV
Sbjct: 142 DIAVFDTEASTGEVINAITSDILVVQDAISEKVGNFMHYISRFLAGFAIGFSQVWQISLV 201
Query: 649 MMGFAPLIVLSG---AKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKREL 819
+ PLI ++G A ++ + R R ++Y AG IAEE ++RTV + G ++ +
Sbjct: 202 TLAIVPLIAIAGGIYAYVTIGLMARVR---KSYVKAGEIAEEVIGNVRTVQAFVGEEKAV 258
Query: 820 DRFYNAL----EVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRG 987
+ AL + G++ G+ K G+G+G + ++ S+AL W+ S ++++ + G
Sbjct: 259 RTYREALLRTYKYGKRGGLAK----GLGLGSMHSVLFLSWALLIWFTS-VVVHKNISNGG 313
Query: 988 LIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMK 1167
FT V+ SLG A P++++F AR AA + ++I + S G + ++
Sbjct: 314 ESFTTMLNVVIAGLSLGQAAPNISTFLRARTAAYPIFQMIERNTVNKASSKAGRTLPSVD 373
Query: 1168 GDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKG 1347
G I F+DV F YPSR D+ +L SL+ AG +ALVG SG GKST+V+L++RFY+P G
Sbjct: 374 GHIQFRDVRFAYPSRPDVVILDRFSLDFPAGKIVALVGGSGSGKSTVVSLIERFYEPLTG 433
Query: 1348 RVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANA 1527
VL+DG D+++++V LR+QIG+V+QEP LF +I ENI G A+ D++ A K++ A
Sbjct: 434 AVLLDGHDIKDLDVKWLRQQIGLVNQEPALFATSIRENILYGKGDASMDEINHAAKLSEA 493
Query: 1528 NDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREV 1707
FI LPD Y T+VGE+G+QLSGGQKQRIAI+RA++KNP ILLLDEATSALD E+E+ V
Sbjct: 494 ITFINHLPDRYETQVGERGIQLSGGQKQRIAISRAILKNPSILLLDEATSALDAESEKSV 553
Query: 1708 QGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYD----- 1872
Q ALD+ GRTT+++AHRLSTIRN D I V +G IVE+G+HE+LM+ Y
Sbjct: 554 QEALDRVMVGRTTVVIAHRLSTIRNADTIAVVDSGRIVETGTHEQLMANPRSAYASLIQL 613
Query: 1873 MTXXXXXXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQL----AEEVEEC 2040
+ +S L + + A +
Sbjct: 614 QEAAQLQNKQSFSDSASLSRPLSSKYSRELSRTSMGGSFRSEKDSVSRYGTVEAHDEGGH 673
Query: 2041 KAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANV 2220
K+ P SM K++ + S P+FAL + Y + + + V
Sbjct: 674 KSKPVSMKKLYSMIRPDWFFGVSGTVSAFVAGSQMPLFALGVTQALVSYYMGWETTKREV 733
Query: 2221 YFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTG 2400
+F + V G GE LT+++R F +LR +I ++DD H +
Sbjct: 734 RKIAVLFCCGAVLTVVFHAIEHLSFGIMGERLTLRVRERMFAAILRNEIGWFDDTSHTSS 793
Query: 2401 KLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGG 2577
L +R TDA VR V R ++L +I I +L I F W+ G
Sbjct: 794 MLSSRLETDATLVRTIVVDRSTILLQNIGMIVTSLIIAFIINWRITLVVLATYPLMVSGH 853
Query: 2578 YFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNL 2757
E G + +A +A++AV +IRTV + +E+ Y + L+EP +
Sbjct: 854 ISEKMFMKGYGGNLGKSYLKANMLAAEAVSNIRTVAAFCAEEKVIKLYADELKEPAKQSF 913
Query: 2758 KHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTT 2937
+ G + SQ +F YA A + GS ++++ V + F + +G T
Sbjct: 914 RRGQGAGLFYGVSQFFLFSSYALALWYGSELMSKEMASFKSVMKSFMVLIVTALAMGETL 973
Query: 2938 SFIPDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTKV 3114
+ PD++K S +F +++ T D L D+G VK + G I +R V F YP R + V
Sbjct: 974 AMAPDIIKGNQMVSSVFEILDRKT--DVLIDAGNDVKRVEGVIELRGVEFRYPARPEVVV 1031
Query: 3115 LQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQ 3294
+G L +KAGK++ALVG SG GKST++ L+ RFY+ G ++IDG +IR + + SLR+
Sbjct: 1032 FKGLDLLMKAGKSMALVGMSGSGKSTVLSLILRFYDPIAGKVLIDGKDIRKVKLKSLRKH 1091
Query: 3295 VCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKG 3474
+ +V QEP LF TI +NI YG + T E+V+AAK+AN H+FI LP+GY T VGE+G
Sbjct: 1092 IGLVQQEPALFATTIYDNILYGKD-GATEAEVVDAAKLANAHSFISALPEGYRTRVGERG 1150
Query: 3475 TQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHR 3654
QLSGGQ+QRIAIARA+V+ P++LLLDEATSALD ESE++VQ+ALD + RT +++AHR
Sbjct: 1151 VQLSGGQRQRIAIARAIVKDPAILLLDEATSALDVESERVVQQALDRVMRNRTTVMVAHR 1210
Query: 3655 LSTIQNSDVIAIVSEGKIVEKGTHDELI-RKSEIYQKFCETQRIVESQ 3795
LSTI+N+DVI+++ +GKI+E+G H +LI ++ Y K Q+ + Q
Sbjct: 1211 LSTIKNADVISVLQDGKIIEQGAHHQLIENRNGAYHKLVSLQQQQQQQ 1258
>gi|25146777|ref|NP_509811.2| P-GlycoProtein related (pgp-8)
[Caenorhabditis elegans]
gi|22265670|emb|CAA94203.2| Hypothetical protein T21E8.3
[Caenorhabditis elegans]
gi|22265925|emb|CAA94221.2| Hypothetical protein T21E8.3
[Caenorhabditis elegans]
Length = 1243
Score = 739 bits (1908), Expect = 0.0
Identities = 440/1234 (35%), Positives = 676/1234 (54%), Gaps = 11/1234 (0%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
++ T + L + G V+A+ G P ++ G ++ F+R + VN
Sbjct: 28 VWQCTSKWEKFLFVIGVVSAICTGLTQPFMSYTFGEVSQAFVRITAA--------VNNAS 79
Query: 292 LVPISLDE----FNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKA 459
L P L++ F++++ I++ ++G F ++Q + F+ + ++LR ++
Sbjct: 80 LDPSDLEKAYEMFHADMNNVVIHFGLVGCAFMFFGFIQFSLFKYIGDNTTYRLRHKFILR 139
Query: 460 ILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSM 639
+L++ ++FD TG L+ L D+LER RE +K A ++ F G + F+ SW++
Sbjct: 140 LLKKDAKYFDTISTGYLSTVLNDNLERFREAFNEKIAFIICFSTDFAIGTALAFYTSWTL 199
Query: 640 TLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKREL 819
FA IV+SG S SM + Y+ AGAIA + S +TV SLNG +EL
Sbjct: 200 ASYGSVFAFGIVISGLLNSTSMMKSNEKQSMHYSNAGAIAFQALCSFKTVISLNGQTQEL 259
Query: 820 DRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFT 999
+++ L+ G + G + ++ G S+ + + G+ LI N T + I T
Sbjct: 260 EKYSAELKEGEKFGSRRAFFLATSRGLSHFFCNALNGTILYVGADLIYNK-TMNTVAIVT 318
Query: 1000 VFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMK---G 1170
+F +L + SLG A H++ A +A+ + V+ S + + + D+ K G
Sbjct: 319 LFHYMLFSAFSLGEAFLHISYLLNAINSATPIFDVLTSDDDMIENNQDNEQTDSNKTIQG 378
Query: 1171 DISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGR 1350
+SF +V F YPSR D+ +L+GIS ++K G+ IALVG+SG GKSTIV LL FY+ G
Sbjct: 379 MLSFNNVKFAYPSRPDVDILRGISFDVKQGECIALVGASGSGKSTIVQLLLHFYNIQSGT 438
Query: 1351 VLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAN 1530
+ I L ++N+ LR IG+VSQEPVLF+ TI ENI+ GN +AT ++ EA + ANA
Sbjct: 439 IKIGDSHLHDINLKQLRNAIGVVSQEPVLFNTTIEENIRFGNPNATSSEIYEALRKANAY 498
Query: 1531 DFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQ 1710
DF+ + DG T VGE+G QLSGGQKQRIAIAR LVKNP ILLLDEATSALD+ +ER VQ
Sbjct: 499 DFVCNIKDGLKTIVGERGAQLSGGQKQRIAIARVLVKNPAILLLDEATSALDSASERAVQ 558
Query: 1711 GALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXX 1890
AL +A GRTTII+AHRLSTIR+ D+I V G I E GSHEEL+S + ++
Sbjct: 559 LALKKASEGRTTIIIAHRLSTIRHCDKIMVMSNGKIAEVGSHEELISMDREYSNLVRAQF 618
Query: 1891 XXXXXXEA---GKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKAPPTSM 2061
E G+ E+ I ++ + + +L +E +++
Sbjct: 619 FDSQSVEEDINGQGAEEVIQKTPPN-----------LNDGEPLEELLKETSSDIEIKSNI 667
Query: 2062 FKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANVYFWCGMF 2241
+++ + P+ + + + + Y++ + + +FW MF
Sbjct: 668 WEVLRECRPDAFLLSMAVIGSAIQGCNFPILSQIIVQTYKAYAMDGENILTYGHFWAAMF 727
Query: 2242 VLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFA 2421
+++G+ + + G+ E L+ +LR ++F++LL AFYDD +H +L R
Sbjct: 728 LVLGVIRPITLYCQFFFFGKVSEKLSTRLRIKSFQHLLSLPCAFYDDPKHSPTRLVNRLN 787
Query: 2422 TDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMR 2598
TD N++ V RL +L S+V+ A+ I YY W+ + +
Sbjct: 788 TDPSNIKAAVDARLGSLLMSMVSFSLAILIACYYSWKLTLQVVLFFPVLYYAKFLYKKTT 847
Query: 2599 FGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYG 2778
D+ E + K+A + +++++TV +LN + + EYL + + + G
Sbjct: 848 TISIKEDSVAFENSNKIAIEVLDNMKTVKALNMEARVINLVMEYLAVLKTSYPRRSVVMG 907
Query: 2779 AVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVV 2958
FS +YA +F G+ + Q+ + P+D+Y +S+ M G+ S++PD
Sbjct: 908 LANGFSAGCSQIVYAISFKFGTYLILQKEVIPMDMYLSLITLSYTSNMAGSAISYMPDFR 967
Query: 2959 KARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDI 3138
KA +A L+F L +P + SD+G G ++ NV F+Y R D VL L +
Sbjct: 968 KAIHSAGLIFNLFTYPATMPFNSDTGSRSITKGEVNGENVKFHYHQRPDYTVLDSVNLKV 1027
Query: 3139 KAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEP 3318
+AGKT+A+VG SG GKSTI+ LLE FY D+G I ID DN+ N+N+ LR + +VSQ P
Sbjct: 1028 EAGKTLAIVGPSGSGKSTIISLLEMFYRADQGFIKIDNDNVENINLDHLRSNLGLVSQGP 1087
Query: 3319 TLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQK 3498
LF+C+I +NI YG RN++ EI A ++AN NF+ LP G DT VG++G QLSGGQK
Sbjct: 1088 VLFNCSIRDNILYGLTRNISQTEIENALQIANAFNFVFQLPQGLDTIVGDRGAQLSGGQK 1147
Query: 3499 QRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSD 3678
QRIAI RA++R+P +LLLDEATSALDTESEKIVQ ALD A + + +V+AHRLSTI N+D
Sbjct: 1148 QRIAITRAILRNPKLLLLDEATSALDTESEKIVQNALDTASERLSTIVVAHRLSTIINAD 1207
Query: 3679 VIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQR 3780
IA++ GK+VE+GTH++L+ Y + + Q+
Sbjct: 1208 SIAVLRNGKVVEQGTHNQLLAVKGDYWRLVQHQK 1241
>gi|7511495|pir||T18940 multidrug resistance protein homolog -
Caenorhabditis elegans
Length = 1238
Score = 738 bits (1905), Expect = 0.0
Identities = 440/1234 (35%), Positives = 677/1234 (54%), Gaps = 11/1234 (0%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
++ T + L + G V+A+ G P ++ G ++ F+R + VN
Sbjct: 28 VWQCTSKWEKFLFVIGVVSAICTGLTQPFMSYTFGEVSQAFVRITAA--------VNNAS 79
Query: 292 LVPISLDE----FNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKA 459
L P L++ F++++ I++ ++G F ++Q + F+ + ++LR ++
Sbjct: 80 LDPSDLEKAYEMFHADMNNVVIHFGLVGCAFMFFGFIQFSLFKYIGDNTTYRLRHKFILR 139
Query: 460 ILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSM 639
+L++ ++FD TG L+ L D+LER RE +K A ++ F G + F+ SW++
Sbjct: 140 LLKKDAKYFDTISTGYLSTVLNDNLERFREAFNEKIAFIICFSTDFAIGTALAFYTSWTL 199
Query: 640 TLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKREL 819
FA IV+SG S SM + Y+ AGAIA + S +TV SLNG +EL
Sbjct: 200 ASYGSVFAFGIVISGLLNSTSMMKSNEKQSMHYSNAGAIAFQALCSFKTVISLNGQTQEL 259
Query: 820 DRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFT 999
+++ L+ G + G + ++ G S+ + + G+ LI N T + I T
Sbjct: 260 EKYSAELKEGEKFGSRRAFFLATSRGLSHFFCNALNGTILYVGADLIYNK-TMNTVAIVT 318
Query: 1000 VFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMK---G 1170
+F +L + SLG A H++ A +A+ + V+ S + + + D+ K G
Sbjct: 319 LFHYMLFSAFSLGEAFLHISYLLNAINSATPIFDVLTSDDDMIENNQDNEQTDSNKTIQG 378
Query: 1171 DISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGR 1350
+SF +V F YPSR D+ +L+GIS ++K G+ IALVG+SG GKSTIV LL FY+ G
Sbjct: 379 MLSFNNVKFAYPSRPDVDILRGISFDVKQGECIALVGASGSGKSTIVQLLLHFYNIQSGT 438
Query: 1351 VLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAN 1530
+ I L ++N+ LR IG+VSQEPVLF+ TI ENI+ GN +AT ++ EA + ANA
Sbjct: 439 IKIGDSHLHDINLKQLRNAIGVVSQEPVLFNTTIEENIRFGNPNATSSEIYEALRKANAY 498
Query: 1531 DFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQ 1710
DF+ + DG T VGE+G QLSGGQKQRIAIAR LVKNP ILLLDEATSALD+ +ER VQ
Sbjct: 499 DFVCNIKDGLKTIVGERGAQLSGGQKQRIAIARVLVKNPAILLLDEATSALDSASERAVQ 558
Query: 1711 GALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXX 1890
AL +A GRTTII+AHRLSTIR+ D+I V G I E GSHEEL+S + ++
Sbjct: 559 LALKKASEGRTTIIIAHRLSTIRHCDKIMVMSNGKIAEVGSHEELISMDREYSNLVRAQF 618
Query: 1891 XXXXXXEA---GKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKAPPTSM 2061
E G+ E+ I ++ + + +L +E +++
Sbjct: 619 FDSQSVEEDINGQGAEEVIQKTPPN-----------LNDGEPLEELLKETSSDIEIKSNI 667
Query: 2062 FKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANVYFWCGMF 2241
+++ + P+ + + + + Y++ + + +FW MF
Sbjct: 668 WEVLRECRPDAFLLSMAVIGSAIQGCNFPILSQIIVQTYKAYAMDGENILTYGHFWAAMF 727
Query: 2242 VLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFA 2421
+++G+ + + G+ E L+ +LR ++F++LL AFYDD +H +L R
Sbjct: 728 LVLGVIRPITLYCQFFFFGKVSEKLSTRLRIKSFQHLLSLPCAFYDDPKHSPTRLVNRLN 787
Query: 2422 TDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMR 2598
TD N++ V RL +L S+V+ A+ I YY W+ + ++
Sbjct: 788 TDPSNIKAAVDARLGSLLMSMVSFSLAILIACYYSWKLTLQAILYYAKFLYKKTTTISIK 847
Query: 2599 FGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYG 2778
D+ E + K+A + +++++TV +LN + + EYL + + + G
Sbjct: 848 -----EDSVAFENSNKIAIEVLDNMKTVKALNMEARVINLVMEYLAVLKTSYPRRSVVMG 902
Query: 2779 AVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVV 2958
FS +YA +F G+ + Q+ + P+D+Y +S+ M G+ S++PD
Sbjct: 903 LANGFSAGCSQIVYAISFKFGTYLILQKEVIPMDMYLSLITLSYTSNMAGSAISYMPDFR 962
Query: 2959 KARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDI 3138
KA +A L+F L +P + SD+G G ++ NV F+Y R D VL L +
Sbjct: 963 KAIHSAGLIFNLFTYPATMPFNSDTGSRSITKGEVNGENVKFHYHQRPDYTVLDSVNLKV 1022
Query: 3139 KAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEP 3318
+AGKT+A+VG SG GKSTI+ LLE FY D+G I ID DN+ N+N+ LR + +VSQ P
Sbjct: 1023 EAGKTLAIVGPSGSGKSTIISLLEMFYRADQGFIKIDNDNVENINLDHLRSNLGLVSQGP 1082
Query: 3319 TLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQK 3498
LF+C+I +NI YG RN++ EI A ++AN NF+ LP G DT VG++G QLSGGQK
Sbjct: 1083 VLFNCSIRDNILYGLTRNISQTEIENALQIANAFNFVFQLPQGLDTIVGDRGAQLSGGQK 1142
Query: 3499 QRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSD 3678
QRIAI RA++R+P +LLLDEATSALDTESEKIVQ ALD A + + +V+AHRLSTI N+D
Sbjct: 1143 QRIAITRAILRNPKLLLLDEATSALDTESEKIVQNALDTASERLSTIVVAHRLSTIINAD 1202
Query: 3679 VIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQR 3780
IA++ GK+VE+GTH++L+ Y + + Q+
Sbjct: 1203 SIAVLRNGKVVEQGTHNQLLAVKGDYWRLVQHQK 1236
>gi|21740907|emb|CAD40903.1| OSJNBa0036B21.21 [Oryza sativa (japonica
cultivar-group)]
Length = 1252
Score = 736 bits (1901), Expect = 0.0
Identities = 447/1256 (35%), Positives = 678/1256 (53%), Gaps = 34/1256 (2%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F + +D LL+ G+ AV+HGA P+ ++ G + F + Q+S
Sbjct: 34 LFGFADPLDWLLMAAGSAGAVVHGAAMPVFFLLFGELINGFGKNQHS------------- 80
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
L EV K QIAC+ ER V LR+ YL+A+LRQ
Sbjct: 81 -----LRRMTDEVSK-----------------AQIACWMYTGERQVGALRRRYLEAVLRQ 118
Query: 472 QIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLV 648
+ +FD +TG++ ++ D V++ +G+K + + FLAG VGF +W + L+
Sbjct: 119 DVGFFDTDARTGDVVFSVSTDTLLVQDAIGEKVGNFIHYLSTFLAGLVVGFVSAWRLALL 178
Query: 649 MMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRF 828
+ P I +G + ++ T +++YA AG IAE+ + +RTV+S G + L+ +
Sbjct: 179 SIAVIPGIAFAGGLYAYTLTGLTSKSRDSYANAGIIAEQAIAQVRTVYSYVGESKALNSY 238
Query: 829 ----YNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIF 996
N L++G + G+ K +GIG + CM S+AL FWY I N T D G F
Sbjct: 239 SEAIQNTLKLGYKAGMAKG--LGIGCTYGIACM--SWALVFWYAGVFIRNGQT-DGGKAF 293
Query: 997 TVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDI 1176
T F+ + G SLG + +L +F + A +L VI P I +G +D + G+I
Sbjct: 294 TAIFSAIVGGLSLGQSFSNLGAFSKGKIAGYKLLEVIRQRPTIVQDPADGRCLDEVHGNI 353
Query: 1177 SFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVL 1356
FK+V F YPSR D+ + + SL AG A+VG SG GKST+V L++RFYDP +G+VL
Sbjct: 354 EFKEVAFSYPSRPDVMIFRDFSLFFPAGKTAAVVGGSGSGKSTVVALIERFYDPNQGQVL 413
Query: 1357 IDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDF 1536
+D VD++ + + LR+QIG+V+QEP LF TI ENI G AT +V A ANA+ F
Sbjct: 414 LDNVDIKTLQLKWLRDQIGLVNQEPALFATTILENILYGKPDATMAEVEAAATSANAHSF 473
Query: 1537 IKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGA 1716
I LP+GY T+VGE+G+QLSGGQKQRIAIARA++KNPKILLLDEATSALD +E VQ A
Sbjct: 474 IALLPNGYNTQVGERGLQLSGGQKQRIAIARAMLKNPKILLLDEATSALDAGSENIVQEA 533
Query: 1717 LDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSK--QGIFYDMTXXXX 1890
LD+ GRTT++VAHRLSTIR VD I V + G +VE+G+H+EL++K G + +
Sbjct: 534 LDRLMVGRTTVVVAHRLSTIRCVDMIAVIQQGQVVETGTHDELLAKGSSGAYAALIRFQE 593
Query: 1891 XXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQL-------------AEEV 2031
G + S + L + A+
Sbjct: 594 MARNRDFRGPSTRKSRSSRLSNSLSTRSLSLRSGSLRNLSYSYSTGADGRIEMVSNADND 653
Query: 2032 EECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNV-YSLPADQM 2208
+ AP FK+ K N + + + P FA+V + + V Y + M
Sbjct: 654 RKYPAPKGYFFKLLKLNAPEWPYTILGAIGSILSGFIGPTFAIVMSNMIEVFYFRDPNAM 713
Query: 2209 QANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLR----------FEAFKNLLR 2358
+ + +++ G+ V + GE+LT ++R F +LR
Sbjct: 714 ERKTREYVFIYIGTGLYAVVAYLVQHYFFSIMGENLTTRVRRMMLAVALFDQRLFSAILR 773
Query: 2359 QDIAFYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXX 2535
D+ ++D + + + R +TDA +V+ + R+ V+L ++ ++ + +GF W+
Sbjct: 774 NDVGWFDQEENNSSLVAARLSTDAADVKSAIAERISVILQNMTSLLVSFVVGFIIEWRVA 833
Query: 2536 XXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHF 2715
+ + + G + + +A + V +IRTV + N Q++
Sbjct: 834 VLILVTFPLLVLANFAQQLSMKGFAGDTAKAHAKTSMIAGEGVSNIRTVAAFNAQDKVLS 893
Query: 2716 TYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVF 2895
+C LR P +L+ + GA+F SQ ++ A + G+ V V +VF
Sbjct: 894 LFCTELRVPQMHSLRRSQISGALFGLSQLSLYASEALILWYGAHLVRHHVSTFSKVIKVF 953
Query: 2896 FAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPID-SLSDSGIVKPITGNISIR 3072
+ + T S P++V+ + +F ++ + T ID ++ V+ + G+I R
Sbjct: 954 VVLVITANTVAETVSLAPEIVRGGESIRSVFAILNYRTRIDPDEPETEPVESVRGDIDFR 1013
Query: 3073 NVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDG 3252
+V F YP+R D V + F+L I+AG++ ALVG SG GKST++ L+ERFY+ G +MIDG
Sbjct: 1014 HVDFAYPSRPDVMVFKDFSLRIRAGQSQALVGASGSGKSTVIALIERFYDPLAGKVMIDG 1073
Query: 3253 DNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFIL 3432
+IR LN+ SLR ++ +V QEP LF +I ENI YG + T +E++EAAK+AN+H F+
Sbjct: 1074 KDIRRLNVRSLRLKIGLVQQEPVLFATSIFENIAYGKD-GATEEEVIEAAKVANMHGFVS 1132
Query: 3433 GLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALD 3612
LP+GY T VGE+G QLSGGQKQRIAIARA+++ P+VLLLDEATSALD ESE ++QEAL+
Sbjct: 1133 ALPEGYKTPVGERGVQLSGGQKQRIAIARAVLKDPAVLLLDEATSALDAESECVLQEALE 1192
Query: 3613 AAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELI-RKSEIYQKFCETQ 3777
+GRT +++AHRLSTI+ D IA+V +G++VE+G+H EL+ R Y + + Q
Sbjct: 1193 RIMKGRTAVLVAHRLSTIRGVDSIAVVQDGRVVEQGSHGELVSRPDGAYSRLLQLQ 1248
>gi|22655312|gb|AAM98246.1| putative ABC transporter [Arabidopsis
thaliana]
Length = 1286
Score = 736 bits (1901), Expect = 0.0
Identities = 439/1259 (34%), Positives = 680/1259 (53%), Gaps = 31/1259 (2%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F + G+D +L+ G+V A +HG PL FLR D VN G
Sbjct: 32 LFRFADGLDYVLMGIGSVGAFVHGCSLPL-----------FLR-------FFADLVNSFG 73
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
++++ EV+KY +Y+LV+G ++ +S+ +I+C+ ER K+R YL+A L Q
Sbjct: 74 SNSNNVEKMMEEVLKYALYFLVVGAAIWASSWAEISCWMWSGERQTTKMRIKYLEAALNQ 133
Query: 472 QIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLV 648
IQ+FD + +T ++ + D V++ + +K + A F++G+ VGF W + LV
Sbjct: 134 DIQFFDTEVRTSDVVFAINTDAVMVQDAISEKLGNFIHYMATFVSGFIVGFTAVWQLALV 193
Query: 649 MMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRF 828
+ PLI + G + +++ + QE+ + AG I E+T IR V + G R +
Sbjct: 194 TLAVVPLIAVIGGIHTTTLSKLSNKSQESLSQAGNIVEQTVVQIRVVMAFVGESRASQAY 253
Query: 829 YNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFF 1008
+AL++ ++ G G+G+G + ++ YAL WY L+ + T + GL F
Sbjct: 254 SSALKIAQKLGYKTGLAKGMGLGATYFVVFCCYALLLWYDGYLVRHHLT-NGGLAIATMF 312
Query: 1009 AVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKD 1188
AV+ G +LG + P +A+F A+ AA+ + R+I+ P I+ S G+ +D++ G + K+
Sbjct: 313 AVMIGGLALGQSAPSMAAFAKAKVAAAKIFRIIDHKPTIERNSESGVELDSVTGLVELKN 372
Query: 1189 VHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGV 1368
V F YPSR D+ +L L + AG IALVGSSG GKST+V+L++RFYDP G+VL+DG
Sbjct: 373 VDFSYPSRPDVKILNNFCLSVPAGKTIALVGSSGSGKSTVVSLIERFYDPNSGQVLLDGQ 432
Query: 1369 DLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRL 1548
DL+ + + LR+QIG+VSQEP LF +I ENI +G A ++ EA ++ANA+ FI +L
Sbjct: 433 DLKTLKLRWLRQQIGLVSQEPALFATSIKENILLGRPDADQVEIEEAARVANAHSFIIKL 492
Query: 1549 PDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQA 1728
PDG+ T+VGE+G+QLSGGQKQRIAIARA++KNP ILLLDEATSALD+E+E+ VQ ALD+
Sbjct: 493 PDGFDTQVGERGLQLSGGQKQRIAIARAMLKNPAILLLDEATSALDSESEKLVQEALDRF 552
Query: 1729 QAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSK--QGIFYD---------- 1872
GRTT+I+AHRLSTIR D + V + G++ E G+H+EL SK G++
Sbjct: 553 MIGRTTLIIAHRLSTIRKADLVAVLQQGSVSEIGTHDELFSKGENGVYAKLIKMQEAAHE 612
Query: 1873 --MTXXXXXXXXXXEAGKDIEDTISESAHSH---------LXXXXXXXXXXXXXXXIHQL 2019
M+ A + I S+
Sbjct: 613 TAMSNARKSSARPSSARNSVSSPIMTRNSSYGRSPYSRRLSDFSTSDFSLSIDASSYPNY 672
Query: 2020 AEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLP- 2196
E K S +++ K N + + S++ FA V + + +VY P
Sbjct: 673 RNEKLAFKDQANSFWRLAKMNSPEWKYALLGSVGSVICGSLSAFFAYVLSAVLSVYYNPD 732
Query: 2197 ADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFY 2376
+ M + +C + + + V + GE+LT ++R + +L+ ++A++
Sbjct: 733 HEYMIKQIDKYCYLLIGLSSAALVFNTLQHSFWDIVGENLTKRVREKMLSAVLKNEMAWF 792
Query: 2377 DDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXX 2553
D + + ++ R A DA NVR + R+ V++ + + A GF W+
Sbjct: 793 DQEENESARIAARLALDANNVRSAIGDRISVIVQNTALMLVACTAGFVLQWRLALVLVAV 852
Query: 2554 XXXXXMGGYFEMQMRFGKQIRDTQLLEEAG-KVASQAVEHIRTVHSLNRQEQFHFTYCEY 2730
+ G D + G ++A +A+ ++RTV + N + + Y
Sbjct: 853 FPVVVAATVLQKMFMTGFS-GDLEAAHAKGTQLAGEAIANVRTVAAFNSEAKIVRLYTAN 911
Query: 2731 LREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISF 2910
L P G+ + +Q ++ YA + S V RVF +
Sbjct: 912 LEPPLKRCFWKGQIAGSGYGVAQFCLYASYALGLWYASWLVKHGISDFSKTIRVFMVLMV 971
Query: 2911 CGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPI--DSLSDSGIVKPITGNISIRNVFF 3084
T + PD +K A +F L++ T I D + + + G + ++++ F
Sbjct: 972 SANGAAETLTLAPDFIKGGQAMRSVFELLDRKTEIEPDDPDTTPVPDRLRGEVELKHIDF 1031
Query: 3085 NYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIR 3264
+YP+R D ++ + +L +AGKT+ALVG SGCGKS+++ L++RFY G +MIDG +IR
Sbjct: 1032 SYPSRPDIQIFRDLSLRARAGKTLALVGPSGCGKSSVISLIQRFYEPSSGRVMIDGKDIR 1091
Query: 3265 NLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPD 3444
N+ ++R+ + IV QEP LF TI ENI YG + T EI++AA +A+ H FI LP+
Sbjct: 1092 KYNLKAIRKHIAIVPQEPCLFGTTIYENIAYG-HECATEAEIIQAATLASAHKFISALPE 1150
Query: 3445 GYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQ 3624
GY T+VGE+G QLSGGQKQRIAIARALVR ++LLD ATSALD ESE+ VQEALD A
Sbjct: 1151 GYKTYVGERGVQLSGGQKQRIAIARALVRKAEIMLLDGATSALDAESERSVQEALDQACS 1210
Query: 3625 GRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRK--SEIYQKFCETQRIVESQ 3795
GRT +V+AHRLSTI+N+ VIA++ +GK+ E+G+H L++ IY + + QR +Q
Sbjct: 1211 GRTSIVVAHRLSTIRNAHVIAVIDDGKVAEQGSHSHLLKNHPDGIYARMIQLQRFTHTQ 1269
>gi|39595964|emb|CAE67467.1| Hypothetical protein CBG12969
[Caenorhabditis briggsae]
Length = 1231
Score = 736 bits (1899), Expect = 0.0
Identities = 437/1208 (36%), Positives = 665/1208 (54%), Gaps = 17/1208 (1%)
Frame = +1
Query: 121 YTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVP 300
Y+ VD LLL G ++ G L AI+ +T V + Q S D+
Sbjct: 38 YSNKVDRLLLGLGIFLSISQGCCSSLNAILFRDLTDVLISGQGSYTNQTFDH-------- 89
Query: 301 ISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQ 480
+FN+E + Y + G L+F S+V + C+ ++ ER + K+R Y A+LRQ +
Sbjct: 90 ---QQFNNETLNIIHTYFLYGTLLFSLSFVSMCCWHTFCERQIFKIRVAYFSALLRQDWE 146
Query: 481 WFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGF 660
WFD+ +G R+ D LERVR+GLGDK +++ F G + F+ S MT+V +
Sbjct: 147 WFDQNDSGAAIVRMNDGLERVRDGLGDKLGVIIAYLTHFFCGLSLAFYLSVEMTIVTLII 206
Query: 661 APLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNAL 840
P +L K ++ T E E Y A A E S I+TV S NG ++E++R+ L
Sbjct: 207 TPAFILPIIISRKMISKVTFKELEAYESAATAAGEVISGIKTVVSFNGEQKEINRYSKFL 266
Query: 841 EVGRQTGIVKYCYMGI-GVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVL 1017
G+ + G+ + C++ + W+G+ L++ + G VF+AV
Sbjct: 267 SKAMYWGLWRASLSSFEGLLGHSSCVFQWQFHSGWWGTRLVLKG-SITPGTTLAVFWAVN 325
Query: 1018 SGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHF 1197
+G A+PHL S + AA V ++I+ +D S +G+ + +KG + F++V F
Sbjct: 326 GAIYFVGQAIPHLTSVSSCYSAAVPVFQIIDRTVILDGTSDKGLKLSKVKGKVKFENVWF 385
Query: 1198 RYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLR 1377
+YP+R+ ++VLKGISL G+ IALVG SG GKST L+ FY+ G++ ID ++
Sbjct: 386 KYPARQKVNVLKGISLHANPGENIALVGHSGSGKSTTAALMMHFYELNGGKISIDDTNID 445
Query: 1378 EVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDG 1557
E+N+ LR +GIVSQEP+LF T+ N+++G +++ CK+ANA+DFI++LP+G
Sbjct: 446 ELNLSHLRNIVGIVSQEPLLFADTVENNMRLGAPDLDDNEMEYYCKLANAHDFIEQLPNG 505
Query: 1558 YGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAG 1737
Y T +G GV+LSGGQ+QRIAIAR L + P IL+LDEATSALD+E+E VQ AL+ A G
Sbjct: 506 YKTAIGNGGVELSGGQRQRIAIARTLARKPSILILDEATSALDSESESLVQIALENAAEG 565
Query: 1738 RTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXXEAG 1917
RTTI +AHRL TIRN +RI+VF G IVE GSH+ELM K G + M E G
Sbjct: 566 RTTITIAHRLGTIRNCNRIYVFDDGKIVEVGSHQELMEKDGHYAKMVQSQEI-----EVG 620
Query: 1918 KDIEDTISE-------------SAHSHLXXXXXXXXXXXXXXXIHQLAE-EVEECKAPPT 2055
E T+ E S+ + ++ + E P+
Sbjct: 621 NRQESTMEEYSFESRRESCDSKSSRQKFSKKTARSCSLTSEKLLSDISPLPIGEENEQPS 680
Query: 2056 SMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANVYFWCG 2235
+ +I ++ + G P+++++Y +F + S D+ +++
Sbjct: 681 TFLEILRYTKPEWGLLAISILISVLRGFNYPIYSILYGRMFRILSTGTDEEKSSNSGMNA 740
Query: 2236 MFVL-MGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCT 2412
+++ +GI + + +G GE LT +LR F N+LRQD ++D H G+L T
Sbjct: 741 IYLTALGIYALIVTMAAGCLIGYVGERLTKRLRILLFTNILRQDGEYFDVPEHAPGRLIT 800
Query: 2413 RFATDAPNVRYVFT-RLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEM 2589
R +TDAPN+R RL V+ + + I F++ F
Sbjct: 801 RLSTDAPNIRAAIDQRLADVIQGFSAVFCGIAIAFWFSPTMALMGLVNVGVLISLQGFIT 860
Query: 2590 QMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAH 2769
+ + +D++ EE ++A +AVE RTV L R++ F + + + NL+
Sbjct: 861 HVLKKRGEKDSERSEEPSRLAIEAVEQHRTVQYLTREQSFVKKFADGMHPIHIRNLQRGI 920
Query: 2770 TYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIP 2949
+A S S F +A + G + V+ P V++V +++ + S+IP
Sbjct: 921 LQSISYALSTSYTSFSFAIGYRFGLLLVDHDLANPFTVFQVIESLNSSSPSLLALGSYIP 980
Query: 2950 DVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFT 3129
+ V+A+++A LLF ++ + IDS ++G + +IS++NV+F Y +L+ FT
Sbjct: 981 EFVRAQISAGLLFQMLRYEPKIDS--NTGKKTTLDSDISLKNVYFGYQVSGRKMILKDFT 1038
Query: 3130 LDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVS 3309
L I++GKT A+VG SGCGKST + LLERFY+ G I N+R+LN+ LR QV +V
Sbjct: 1039 LKIESGKTTAIVGASGCGKSTTIQLLERFYDPIAGRIDFGSTNLRDLNLKHLRSQVALVE 1098
Query: 3310 QEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSG 3489
QEPTLF+ +I +NI YG ++ E+++AAK+A+ H FI LP+GYDT VGE G++LSG
Sbjct: 1099 QEPTLFNYSIRKNIAYGLE-SIKEGEVIQAAKIAHAHEFITSLPEGYDTIVGEGGSKLSG 1157
Query: 3490 GQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQ 3669
GQKQRIAIARA+VR+P +LLLDEA SALD ESE++VQEAL+ AK+GRTC+VIAHRL+TI+
Sbjct: 1158 GQKQRIAIARAIVRNPKILLLDEAMSALDVESERLVQEALEKAKEGRTCVVIAHRLTTIR 1217
Query: 3670 NSDVIAIV 3693
+ +I IV
Sbjct: 1218 GALLILIV 1225
Score = 276 bits (707), Expect = 2e-72
Identities = 179/519 (34%), Positives = 268/519 (51%), Gaps = 4/519 (0%)
Frame = +1
Query: 2239 FVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRF 2418
+ L G F F S C E K+R F LLRQD ++D ++ +G R
Sbjct: 103 YFLYGTLLFSLSFVSMCCWHTFCERQIFKIRVAYFSALLRQDWEWFD--QNDSGAAIVRM 160
Query: 2419 ATDAPNVRY-VFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQM 2595
VR + +L V++A + L + FY + + +M
Sbjct: 161 NDGLERVRDGLGDKLGVIIAYLTHFFCGLSLAFYLSVEMTIVTLIITPAFILPIIISRKM 220
Query: 2596 RFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAH-- 2769
++ + E A A + + I+TV S N +++ Y ++L + L A
Sbjct: 221 ISKVTFKELEAYESAATAAGEVISGIKTVVSFNGEQKEINRYSKFLSKAMYWGLWRASLS 280
Query: 2770 TYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIP 2949
++ + S + + + + ++ G+ V + ++ P VF+A++ +G +
Sbjct: 281 SFEGLLGHSSCVFQWQFHSGWW-GTRLVLKGSITPGTTLAVFWAVNGAIYFVGQAIPHLT 339
Query: 2950 DVVKARLAASLLFYLIEHPTPIDSLSDSGI-VKPITGNISIRNVFFNYPTRKDTKVLQGF 3126
V AA +F +I+ +D SD G+ + + G + NV+F YP R+ VL+G
Sbjct: 340 SVSSCYSAAVPVFQIIDRTVILDGTSDKGLKLSKVKGKVKFENVWFKYPARQKVNVLKGI 399
Query: 3127 TLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIV 3306
+L G+ +ALVGHSG GKST L+ FY + G I ID NI LN+S LR V IV
Sbjct: 400 SLHANPGENIALVGHSGSGKSTTAALMMHFYELNGGKISIDDTNIDELNLSHLRNIVGIV 459
Query: 3307 SQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLS 3486
SQEP LF T+ N+ G ++ E+ K+AN H+FI LP+GY T +G G +LS
Sbjct: 460 SQEPLLFADTVENNMRLGAP-DLDDNEMEYYCKLANAHDFIEQLPNGYKTAIGNGGVELS 518
Query: 3487 GGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTI 3666
GGQ+QRIAIAR L R PS+L+LDEATSALD+ESE +VQ AL+ A +GRT + IAHRL TI
Sbjct: 519 GGQRQRIAIARTLARKPSILILDEATSALDSESESLVQIALENAAEGRTTITIAHRLGTI 578
Query: 3667 QNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRI 3783
+N + I + +GKIVE G+H EL+ K Y K ++Q I
Sbjct: 579 RNCNRIYVFDDGKIVEVGSHQELMEKDGHYAKMVQSQEI 617
>gi|5733124|gb|AAD49436.1| P-glycoprotein [Onchocerca volvulus]
Length = 1278
Score = 735 bits (1898), Expect = 0.0
Identities = 426/1234 (34%), Positives = 666/1234 (53%), Gaps = 23/1234 (1%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNP 285
+ +F + D +L + A+ G G P++ ++ G +T VFL + +
Sbjct: 49 FQLFRFATTCDRFMLSISALLAIFTGIGQPMICLIGGKLTNVFLLTKTFE---------- 98
Query: 286 EGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAIL 465
D F + Y Y +G+ M T+ +Q C ++ + + +RQ Y+K++L
Sbjct: 99 ------RNDTFWYQAYIYVYLYASIGITMVITTTIQYICAKNASLNITCTMRQEYMKSLL 152
Query: 466 RQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTL 645
RQ+ WFD+Q+TG LTA+L ++E++++G+GDK ++++ FL +GF Y W +TL
Sbjct: 153 RQEAAWFDQQKTGTLTAQLNANIEKIKDGIGDKVGMILRGVTMFLTCVIIGFIYDWRLTL 212
Query: 646 VMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDR 825
VM G P+ + M++ M + ++ T A A+ EE+ +++TV + N + + R
Sbjct: 213 VMFGTGPISAALLSTMARQMEHSSSMQSNTDGRAAAVLEESIMNVKTVAACNAQETMIKR 272
Query: 826 FYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVF 1005
+ L+ R+ + Y + G G L +Y +A F+YG+ L + G IF V
Sbjct: 273 YAATLKACRKFALHAYAFAGFFDGLFFLVLYVFFAAGFYYGAYLYQIRIIMNPGYIFAVA 332
Query: 1006 FAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFK 1185
++ GS +LG PHL + AR AA+ + ++IN P D S +G+ V+ +KG+I F+
Sbjct: 333 NLIMFGSYNLGVLSPHLMAVLNARVAAAVIYKIINRKPSFDSSSTDGMKVNEVKGEIEFQ 392
Query: 1186 DVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDG 1365
+V F YP K+ VL G+S K GD +ALVG SGCGKST LL R Y+ G +LIDG
Sbjct: 393 NVKFSYPKSKEHLVLNGLSWTAKPGDTVALVGHSGCGKSTSTGLLTRLYNCNSGAILIDG 452
Query: 1366 VDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKR 1545
+++ ++N+H+LR +G+V QEP+LF GTI ENI++G T ++++ACK+ANA+DFI +
Sbjct: 453 INICDINIHTLRNIVGVVQQEPLLFSGTIKENIRLGKLDLTDQEIIDACKIANAHDFINK 512
Query: 1546 LPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQ 1725
L +GY T +G G+QLSGGQKQRIAIAR +V+NP+ILLLDEATSALD E+E VQ AL +
Sbjct: 513 LSEGYDTMIGAGGIQLSGGQKQRIAIARTIVRNPRILLLDEATSALDAESEVIVQNALKK 572
Query: 1726 AQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELM-SKQGIFYDMTXXXXXXXX 1902
A GRTTII+AHRLST+R+ ++I V G + E G+H+EL +K GI+ +
Sbjct: 573 AFVGRTTIIIAHRLSTLRDSNQIIVLDKGQVAEIGTHKELCNNKDGIYASLVKSQQFEAQ 632
Query: 1903 XXEAGKDIEDTISESAHSH------------LXXXXXXXXXXXXXXXIHQLAEEVEEC-- 2040
+E+ E+ H + + E+ E
Sbjct: 633 QKPTSPPVEELPLETFHRSNTRDSRNSSGYGIMSSFTRGSIMSGNVTCVSIPEKSTEITV 692
Query: 2041 ------KAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYS-LPA 2199
K+ P +++++ G P+F L++ F V++
Sbjct: 693 ELNGKKKSKPKGLWQLYTNCHGNYGKMIIALLVSFLRGLELPLFVLIFDLTFVVFAQAKL 752
Query: 2200 DQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYD 2379
+ + + +++ +GI + F++ G E + LR A +N+L Q+ ++D
Sbjct: 753 ESVLERILPIAIIYIALGIACLIVIFSATFTFGWTAECVVDSLRLRAMRNMLYQNAEYFD 812
Query: 2380 DLRHGTGKLCTRFATDAPNVRYVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXX 2559
T TR + DA ++ + +IV I + I + W
Sbjct: 813 TPSTSTAVTVTRISVDAQTLKRSRSANDANFDNIVAILVLVTIAVIFNWPVGLLAVKSPV 872
Query: 2560 XXXMGGYFEMQMRFGKQIRDTQLLE-EAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLR 2736
++ ++ ++ L + G++A + VE IRT+ + +E FH Y + +
Sbjct: 873 THFDA---DIDRKYNAEVNKCALKQIVTGQLALEIVEQIRTIQLITGEEHFHRLYVQTIE 929
Query: 2737 EPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCG 2916
+ K + +FA + S +FF ++ G + P +++ ++I+ G
Sbjct: 930 DLLYLQKKSSPYEAILFAVTSSFMFFSDMISYAAGIALIYYGYSLPQEIFTASWSIATSG 989
Query: 2917 QMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPT 3096
+ + + V A A++ LF +I + ++S+ D G+ ITG++ + F+YPT
Sbjct: 990 WALIMVSGCLNTFVMASPASNSLFRIINTGSDMNSV-DDGLRPAITGDVQFNKIKFSYPT 1048
Query: 3097 RKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNI 3276
R VL G L AG+TVA+ G SG GKST++ LLERFY + G + +D ++I +++
Sbjct: 1049 RPQRNVLNGLNLAAYAGQTVAVTGPSGSGKSTVIALLERFYRFNSGQLTLDDNSITKISL 1108
Query: 3277 SSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDT 3456
LREQ+ +V QEP LF TI ENI GT T ++ EA K+ANI +FI P GYDT
Sbjct: 1109 RYLREQIALVGQEPILFSGTILENILLGTT-GKTLSDVREACKIANIIDFIETSPKGYDT 1167
Query: 3457 HVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTC 3636
VGE G QLSGGQKQRIAIARALVR+P +LLLDEATSALD E E+ VQ+ALDAA GRTC
Sbjct: 1168 EVGEHGVQLSGGQKQRIAIARALVRNPKILLLDEATSALDAECERTVQQALDAASSGRTC 1227
Query: 3637 LVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELI 3738
+ +AHRLS+IQ++D I V GK+VE+GTH EL+
Sbjct: 1228 ITVAHRLSSIQHADQIFFVENGKVVEEGTHQELV 1261
Score = 315 bits (808), Expect = 4e-84
Identities = 210/600 (35%), Positives = 318/600 (53%), Gaps = 12/600 (2%)
Frame = +1
Query: 2032 EECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSV-TPVFALVYAEIFNVYSLPA--- 2199
++ A P S F++F+F + + P+ L+ ++ NV+ L
Sbjct: 39 QKLDAKPVSFFQLFRFATTCDRFMLSISALLAIFTGIGQPMICLIGGKLTNVFLLTKTFE 98
Query: 2200 --DQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAF 2373
D Y + ++ +GIT + C ++T +R E K+LLRQ+ A+
Sbjct: 99 RNDTFWYQAYIYVYLYASIGITMVITTTIQYICAKNASLNITCTMRQEYMKSLLRQEAAW 158
Query: 2374 YDDLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXX 2550
+D + TG L + + ++ + ++ ++L + + IGF Y W+
Sbjct: 159 FDQQK--TGTLTAQLNANIEKIKDGIGDKVGMILRGVTMFLTCVIIGFIYDWRLTLVMFG 216
Query: 2551 XX-XXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCE 2727
+ QM ++ + A V +++ +++TV + N QE Y
Sbjct: 217 TGPISAALLSTMARQMEHSSSMQ-SNTDGRAAAVLEESIMNVKTVAACNAQETMIKRYAA 275
Query: 2728 YLREPFNTNLKHAHTYGAVFAFSQSLIFFMY-AAAFYLGS-IFVNQQAMQPIDVYRVFFA 2901
L+ L HA+ + F L+ +++ AA FY G+ ++ + M P ++ V
Sbjct: 276 TLKACRKFAL-HAYAFAGFFDGLFFLVLYVFFAAGFYYGAYLYQIRIIMNPGYIFAVANL 334
Query: 2902 ISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGI-VKPITGNISIRNV 3078
I F +G + + V+ AR+AA++++ +I DS S G+ V + G I +NV
Sbjct: 335 IMFGSYNLGVLSPHLMAVLNARVAAAVIYKIINRKPSFDSSSTDGMKVNEVKGEIEFQNV 394
Query: 3079 FFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDN 3258
F+YP K+ VL G + K G TVALVGHSGCGKST GLL R YN + G I+IDG N
Sbjct: 395 KFSYPKSKEHLVLNGLSWTAKPGDTVALVGHSGCGKSTSTGLLTRLYNCNSGAILIDGIN 454
Query: 3259 IRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGL 3438
I ++NI +LR V +V QEP LF TI ENI G ++T QEI++A K+AN H+FI L
Sbjct: 455 ICDINIHTLRNIVGVVQQEPLLFSGTIKENIRLG-KLDLTDQEIIDACKIANAHDFINKL 513
Query: 3439 PDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAA 3618
+GYDT +G G QLSGGQKQRIAIAR +VR+P +LLLDEATSALD ESE IVQ AL A
Sbjct: 514 SEGYDTMIGAGGIQLSGGQKQRIAIARTIVRNPRILLLDEATSALDAESEVIVQNALKKA 573
Query: 3619 KQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELI-RKSEIYQKFCETQRIVESQ 3795
GRT ++IAHRLST+++S+ I ++ +G++ E GTH EL K IY ++Q+ Q
Sbjct: 574 FVGRTTIIIAHRLSTLRDSNQIIVLDKGQVAEIGTHKELCNNKDGIYASLVKSQQFEAQQ 633
Score = 286 bits (733), Expect = 2e-75
Identities = 197/588 (33%), Positives = 302/588 (50%), Gaps = 12/588 (2%)
Frame = +1
Query: 148 LITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSE 327
+I + + + G PL ++ VF +A+ + E ++PI+
Sbjct: 719 MIIALLVSFLRGLELPLFVLIFDLTFVVFAQAKLESVL--------ERILPIA------- 763
Query: 328 VVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGN 507
I Y+ LG+ + F AE +V LR ++ +L Q ++FD T
Sbjct: 764 -----IIYIALGIACLIVIFSATFTFGWTAECVVDSLRLRAMRNMLYQNAEYFDTPSTST 818
Query: 508 LTA--RLTDD---LERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLI 672
R++ D L+R R F +V A L + ++W + L+ + +
Sbjct: 819 AVTVTRISVDAQTLKRSRSANDANFDNIV----AILVLVTIAVIFNWPVGLLAVKSP--V 872
Query: 673 VLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNG----HKRELDRFYNAL 840
A + + V G +A E IRT+ + G H+ + + L
Sbjct: 873 THFDADIDRKYNAEVNKCALKQIVTGQLALEIVEQIRTIQLITGEEHFHRLYVQTIEDLL 932
Query: 841 EVGRQTG---IVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFA 1011
+ +++ + + + FS++ Y++ +YG +L IFT ++
Sbjct: 933 YLQKKSSPYEAILFAVTSSFMFFSDMISYAAGIALIYYGYSLPQE--------IFTASWS 984
Query: 1012 VLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDV 1191
+ + +L L +F A A++++ R+IN+ D S++ L + GD+ F +
Sbjct: 985 IATSGWALIMVSGCLNTFVMASPASNSLFRIINTGS--DMNSVDDGLRPAITGDVQFNKI 1042
Query: 1192 HFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVD 1371
F YP+R +VL G++L AG +A+ G SG GKST++ LL+RFY G++ +D
Sbjct: 1043 KFSYPTRPQRNVLNGLNLAAYAGQTVAVTGPSGSGKSTVIALLERFYRFNSGQLTLDDNS 1102
Query: 1372 LREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLP 1551
+ ++++ LREQI +V QEP+LF GTI ENI +G T V EACK+AN DFI+ P
Sbjct: 1103 ITKISLRYLREQIALVGQEPILFSGTILENILLGTTGKTLSDVREACKIANIIDFIETSP 1162
Query: 1552 DGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQ 1731
GY T VGE GVQLSGGQKQRIAIARALV+NPKILLLDEATSALD E ER VQ ALD A
Sbjct: 1163 KGYDTEVGEHGVQLSGGQKQRIAIARALVRNPKILLLDEATSALDAECERTVQQALDAAS 1222
Query: 1732 AGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM 1875
+GRT I VAHRLS+I++ D+IF + G +VE G+H+EL+ G + D+
Sbjct: 1223 SGRTCITVAHRLSSIQHADQIFFVENGKVVEEGTHQELVEFDGKYADL 1270
>gi|15229473|ref|NP_189475.1| ABC transporter family protein
[Arabidopsis thaliana]
Length = 1240
Score = 734 bits (1894), Expect = 0.0
Identities = 443/1229 (36%), Positives = 679/1229 (55%), Gaps = 18/1229 (1%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
IF + GVD LL+ G + AV G PL+ ++ + +N G
Sbjct: 23 IFMHADGVDWLLMGLGLIGAVGDGFTTPLVLLITSKL------------------MNNIG 64
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
+ D F + K + L + + +++ C+ ER ++R+ YL+A+LRQ
Sbjct: 65 GSSFNTDTFMQSISKNSVALLYVACGSWVVCFLEGYCWTRTGERQTARMREKYLRAVLRQ 124
Query: 472 QIQWFDKQ--QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTL 645
+ +FD T ++ ++ D +++ L +K + + F+ Y VGF W + +
Sbjct: 125 DVGYFDLHVTSTSDVITSVSSDSFVIQDVLSEKLPNFLMSASTFVGSYIVGFILLWRLAI 184
Query: 646 VMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDR 825
V + F L+V+ G +++ + +R +E Y AG +AE+ SS+RTV++ +G ++ + +
Sbjct: 185 VGLPFIVLLVIPGLMYGRALISISRKIREEYNEAGFVAEQAISSVRTVYAFSGERKTISK 244
Query: 826 FYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVF 1005
F AL+ + GI + GI +G SN ++ + WYGS +++ G +F V
Sbjct: 245 FSTALQGSVKLGIKQGLAKGITIG-SNGITFAMWGFMSWYGSRMVMYHGA-QGGTVFAVA 302
Query: 1006 FAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFK 1185
A+ G SLGG L +L F A ++ VIN PKID + +G ++ ++G++ FK
Sbjct: 303 AAIAIGGVSLGGGLSNLKYFFEAASVGERIMEVINRVPKIDSDNPDGHKLEKIRGEVEFK 362
Query: 1186 DVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDG 1365
+V F YPSR + + L + +G +ALVG SG GKST+++LLQRFYDP G +LIDG
Sbjct: 363 NVKFVYPSRLETSIFDDFCLRVPSGKTVALVGGSGSGKSTVISLLQRFYDPLAGEILIDG 422
Query: 1366 VDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKR 1545
V + ++ V LR Q+G+VSQEP LF TI ENI G E A+ D VVEA K +NA++FI +
Sbjct: 423 VSIDKLQVKWLRSQMGLVSQEPALFATTIKENILFGKEDASMDDVVEAAKASNAHNFISQ 482
Query: 1546 LPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQ 1725
LP+GY T+VGE+GVQ+SGGQKQRIAIARA++K+P ILLLDEATSALD+E+ER VQ AL+
Sbjct: 483 LPNGYETQVGERGVQMSGGQKQRIAIARAIIKSPTILLLDEATSALDSESERVVQEALEN 542
Query: 1726 AQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSK-----------QGIFYD 1872
A GRTTI++AHRLSTIRN D I V K G+IVE+GSH+ELM Q I
Sbjct: 543 ASIGRTTILIAHRLSTIRNADVISVVKNGHIVETGSHDELMENIDGQYSTLVHLQQIEKQ 602
Query: 1873 MTXXXXXXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKAPP 2052
+ KDI ++ S S I L+E+ P
Sbjct: 603 DINVSVKIGPISDPSKDIRNSSRVSTLSR----SSSANSVTGPSTIKNLSED----NKPQ 654
Query: 2053 TSMFK-IFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPA-DQMQANVYF 2226
FK + N + ++ P +A + +VY L + D+++
Sbjct: 655 LPSFKRLLAMNLPEWKQALYGCISATLFGAIQPAYAYSLGSMVSVYFLTSHDEIKEKTRI 714
Query: 2227 WCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKL 2406
+ FV + + F+ + GE LT ++R +L ++ ++D + +G +
Sbjct: 715 YALSFVGLAVLSFLINISQHYNFAYMGEYLTKRIRERMLSKVLTFEVGWFDRDENSSGAI 774
Query: 2407 CTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYF 2583
C+R A DA VR V R+ +V+ ++ + A +G W+ + Y
Sbjct: 775 CSRLAKDANVVRSLVGDRMALVVQTVSAVTIAFTMGLVIAWRLALVMIAVQPVIIVCFYT 834
Query: 2584 EMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKH 2763
+ + + +E+ K+A++AV ++RT+ + + QE+ + P +++
Sbjct: 835 RRVLLKSMSKKAIKAQDESSKLAAEAVSNVRTITAFSSQERIMKMLEKAQESPRRESIRQ 894
Query: 2764 AHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSF 2943
+ G A SQSL +A F+ G + + ++ F + G++I + S
Sbjct: 895 SWFAGFGLAMSQSLTSCTWALDFWYGGRLIQDGYITAKALFETFMILVSTGRVIADAGSM 954
Query: 2944 IPDVVKARLAASLLFYLIEHPTPIDSLSDSGI-VKPITGNISIRNVFFNYPTRKDTKVLQ 3120
D+ K A +F +++ T ID G + ITG + +V F+YPTR D + +
Sbjct: 955 TTDLAKGSDAVGSVFAVLDRYTSIDPEDPDGYETERITGQVEFLDVDFSYPTRPDVIIFK 1014
Query: 3121 GFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVC 3300
F++ I+ GK+ A+VG SG GKSTI+GL+ERFY+ KG++ IDG +IR+ ++ SLR +
Sbjct: 1015 NFSIKIEEGKSTAIVGPSGSGKSTIIGLIERFYDPLKGIVKIDGRDIRSYHLRSLRRHIA 1074
Query: 3301 IVSQEPTLFDCTIGENICYG-TNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGT 3477
+VSQEPTLF TI ENI YG + + EI+EAAK AN H+FI L +GYDT+ G++G
Sbjct: 1075 LVSQEPTLFAGTIRENIIYGGVSDKIDEAEIIEAAKAANAHDFITSLTEGYDTYCGDRGV 1134
Query: 3478 QLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRL 3657
QLSGGQKQRIAIARA++++PSVLLLDEATSALD++SE++VQ+AL+ GRT +VIAHRL
Sbjct: 1135 QLSGGQKQRIAIARAVLKNPSVLLLDEATSALDSQSERVVQDALERVMVGRTSVVIAHRL 1194
Query: 3658 STIQNSDVIAIVSEGKIVEKGTHDELIRK 3744
STIQN D IA++ +GK+VE+GTH L+ K
Sbjct: 1195 STIQNCDAIAVLDKGKLVERGTHSSLLSK 1223
>gi|46390962|dbj|BAD16475.1| putative multidrug resistance
p-glycoprotein [Oryza sativa (japonica cultivar-group)]
Length = 1245
Score = 733 bits (1892), Expect = 0.0
Identities = 446/1227 (36%), Positives = 676/1227 (54%), Gaps = 16/1227 (1%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F + D+ L++ G + A+ G P++ ++ + +F +D G D V
Sbjct: 23 VFMHADAADVALMVLGLLGAMGDGISTPVMLLIT---SRIF-----NDLGSGADIVK--- 71
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
EF+S+V + L + ++++ C+ AER ++R YL+A+LRQ
Sbjct: 72 -------EFSSKVNVNARNLVFLAAASWVMAFLEGYCWARTAERQASRMRARYLRAVLRQ 124
Query: 472 QIQWFD--KQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTL 645
+++FD K T + +++D V++ L +K V A F Y VGF W +TL
Sbjct: 125 DVEYFDLKKGSTAEVITSVSNDSLVVQDVLSEKVPNFVMNAAMFAGSYAVGFALLWRLTL 184
Query: 646 VMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDR 825
V + L+++ G + + R +E Y GAIAE+ SS RTV+S + + +
Sbjct: 185 VALPSVVLLIIPGFMYGRILVGLARRIREQYTRPGAIAEQAVSSARTVYSFVAERTTMAQ 244
Query: 826 FYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVF 1005
F ALE + G+ + GI VG SN ++ +A WYGS L++ + G +F V
Sbjct: 245 FSAALEESARLGLKQGLAKGIAVG-SNGITFAIWAFNVWYGSRLVMYHG-YQGGTVFAVS 302
Query: 1006 FAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFK 1185
A++ G +LG L ++ F A AA +L VI PKID S G + N+ G++ F+
Sbjct: 303 AAIVVGGLALGSGLSNVKYFSEASSAAERILEVIRRVPKIDSESDTGEELANVTGEVEFR 362
Query: 1186 DVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDG 1365
+V F YPSR + + +L + AG +ALVG SG GKST++ LL+RFYDP+ G V++DG
Sbjct: 363 NVEFCYPSRPESPIFVSFNLRVPAGRTVALVGGSGSGKSTVIALLERFYDPSAGEVMVDG 422
Query: 1366 VDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKR 1545
VD+R + + LR Q+G+VSQEP LF +I ENI G E AT ++VV A K ANA++FI +
Sbjct: 423 VDIRRLRLKWLRAQMGLVSQEPALFATSIRENILFGKEEATAEEVVAAAKAANAHNFISQ 482
Query: 1546 LPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQ 1725
LP GY T+VGE+GVQ+SGGQKQRIAIARA++K+PKILLLDEATSALDTE+ER VQ ALD
Sbjct: 483 LPQGYDTQVGERGVQMSGGQKQRIAIARAILKSPKILLLDEATSALDTESERVVQEALDL 542
Query: 1726 AQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXX 1905
A GRTTI++AHRLSTIRN D I V ++G + E G H+EL++ Y
Sbjct: 543 ASMGRTTIVIAHRLSTIRNADIIAVMQSGEVKELGPHDELIANDNGLYSSLVRLQQTRDS 602
Query: 1906 XEAGK----DIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEE--VEECKAPPTSMFK 2067
E + + +S+ + + ++ E+ K P S +
Sbjct: 603 NEIDEIGVTGSTSAVGQSSSHSMSRRFSAASRSSSARSLGDARDDDNTEKPKLPVPSFRR 662
Query: 2068 IFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLP-----ADQMQANVYFWC 2232
+ N + + P +A + +VY L D+ + +
Sbjct: 663 LLMLNAPEWKQALMGSFSAVVFGGIQPAYAYAMGSMISVYFLTDHAEIKDKTRTYALIFV 722
Query: 2233 GMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCT 2412
G+ VL +F + N G GE LT ++R + +L +I ++D + +G +C+
Sbjct: 723 GLAVL---SFLINIGQHYN-FGAMGEYLTKRIREQMLAKILTFEIGWFDRDENSSGAICS 778
Query: 2413 RFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEM 2589
+ A DA VR V R+ +V+ +I + A +G W+ + Y
Sbjct: 779 QLAKDANVVRSLVGDRMALVIQTISAVLIACTMGLVIAWRLALVMIAVQPLIIVCFYARR 838
Query: 2590 QMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAH 2769
+ + E+ K+A++AV ++RT+ + + QE+ + + P +++ +
Sbjct: 839 VLLKSMSKKSIHAQAESSKLAAEAVSNLRTITAFSSQERILRLFEQSQDGPRKESIRQSW 898
Query: 2770 TYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIP 2949
G S SL+ +A F+ G + + + ++++ F + G++I + S
Sbjct: 899 FAGLGLGTSMSLMTCTWALDFWYGGRLMAEHHISAKELFQTFMILVSTGRVIADAGSMTT 958
Query: 2950 DVVKARLAASLLFYLIEHPTPIDSLSDSGIVKP--ITGNISIRNVFFNYPTRKDTKVLQG 3123
D+ K A + +F +++ T ID + G KP + G + IR V F YP+R D + +G
Sbjct: 959 DLAKGADAVASVFAVLDRETEIDPDNPQG-YKPEKLKGEVDIRGVDFAYPSRPDVIIFKG 1017
Query: 3124 FTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCI 3303
FTL I+ GK+ ALVG SG GKSTI+GL+ERFY+ +G + IDG +I+ N+ +LR + +
Sbjct: 1018 FTLSIQPGKSTALVGQSGSGKSTIIGLIERFYDPIRGSVKIDGRDIKAYNLRALRRHIGL 1077
Query: 3304 VSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQL 3483
VSQEPTLF TI ENI YGT + EI +AA+ AN H+FI L DGYDT GE+G QL
Sbjct: 1078 VSQEPTLFAGTIRENIVYGT-ETASEAEIEDAARSANAHDFISNLKDGYDTWCGERGVQL 1136
Query: 3484 SGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLST 3663
SGGQKQRIAIARA++++P++LLLDEATSALD++SEK+VQEALD GRT +V+AHRLST
Sbjct: 1137 SGGQKQRIAIARAILKNPAILLLDEATSALDSQSEKVVQEALDRVMIGRTSVVVAHRLST 1196
Query: 3664 IQNSDVIAIVSEGKIVEKGTHDELIRK 3744
IQN D+I ++ +G +VEKGTH L+ K
Sbjct: 1197 IQNCDLITVLEKGTVVEKGTHASLMAK 1223
>gi|7442651|pir||T14805 hypothetical protein F15J5.20 - Arabidopsis
thaliana
gi|5816991|emb|CAB53646.1| multidrug resistance
protein/P-glycoprotein-like [Arabidopsis thaliana]
Length = 1222
Score = 731 bits (1887), Expect = 0.0
Identities = 435/1225 (35%), Positives = 662/1225 (53%), Gaps = 52/1225 (4%)
Frame = +1
Query: 94 KLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVD 273
K++ + +F + D++L+ GT+AA +G P + ++ G + F
Sbjct: 15 KVSFFKLFSFADKTDVVLMTVGTIAAAGNGLTQPFMTLIFGQLINAF------------G 62
Query: 274 NVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYL 453
+P+ +V EV K + ++ L V +++Q++C+ ER +R YL
Sbjct: 63 TTDPDHMV--------REVWKVAVKFIYLAVYSCVVAFLQVSCWMVTGERQSATIRGLYL 114
Query: 454 KAILRQQIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYS 630
K ILRQ I +FD + TG + R++ D +++ +G+K Q+ FL G+ + F+
Sbjct: 115 KTILRQDIGYFDTETNTGEVIGRMSGDTILIQDAMGEKVGKFTQLLCTFLGGFAIAFYKG 174
Query: 631 WSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHK 810
+ V+ PLIV++GA MS M+ Q YA AG + E+T +IRTV + G K
Sbjct: 175 PLLAGVLCSCIPLIVIAGAAMSLIMSKMAGRGQVAYAEAGNVVEQTVGAIRTVVAFTGEK 234
Query: 811 RELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGL 990
+ +++ + LE+ +T + + G G+G ++ SY LA WYG+ LI+ + ++ G
Sbjct: 235 QATEKYESKLEIAYKTVVQQGLISGFGLGTMLAVIFCSYGLAVWYGAKLIM-EKGYNGGQ 293
Query: 991 IFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKG 1170
+ V FAVL+G SLG P L +F R AA + I PKID Y + G ++++++G
Sbjct: 294 VINVIFAVLTGGMSLGQTSPSLNAFAAGRAAAFKMFETIKRSPKIDAYDMSGSVLEDIRG 353
Query: 1171 DISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGR 1350
DI KDV+FRYP+R D+ + G SL + G +ALVG SG GKST+++L++RFYDP G+
Sbjct: 354 DIELKDVYFRYPARPDVQIFAGFSLFVPNGKTVALVGQSGSGKSTVISLIERFYDPESGQ 413
Query: 1351 VLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAN 1530
VLID +DL+++ + +R +IG+VSQEPVLF TI ENI G E AT ++ A ++ANA
Sbjct: 414 VLIDNIDLKKLQLKWIRSKIGLVSQEPVLFATTIKENIAYGKEDATDQEIRTAIELANAA 473
Query: 1531 DFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQ 1710
FI +LP G T VGE G Q+SGGQKQR+AIARA++KNPKILLLDEATSALD E+ER VQ
Sbjct: 474 KFIDKLPQGLDTMVGEHGTQMSGGQKQRLAIARAILKNPKILLLDEATSALDAESERIVQ 533
Query: 1711 GALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELM-SKQGIFYDM---- 1875
AL + RTT++VAHRL+TIR D I V G IVE G+H+E++ +G + +
Sbjct: 534 DALVNLMSNRTTVVVAHRLTTIRTADVIAVVHQGKIVEKGTHDEMIQDPEGAYSQLVRLQ 593
Query: 1876 --TXXXXXXXXXXEAGKDIE------------DTISESAHSHLXXXXXXXXXXXXXXXIH 2013
+ E D+E ++S ++ S ++
Sbjct: 594 EGSKEEATESERPETSLDVERSGSLRLSSAMRRSVSRNSSSSRHSFSLASNMFFPGVNVN 653
Query: 2014 Q---LAEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNV 2184
Q + +E + S+ ++ N ++ +V P+F L+ + N+
Sbjct: 654 QTDEMEDEENNVRHKKVSLKRLAHLNKPEIPVLVLGSIAAMVHGTVFPIFGLLLSSSINM 713
Query: 2185 YSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQD 2364
+ PA ++ + +FW +++ +G+T FV G G L ++R F ++ Q+
Sbjct: 714 FYEPAKILKKDSHFWALIYIALGLTNFVMIPVPNYFFGIAGGKLIKRIRSMCFDKVVHQE 773
Query: 2365 IAFYDDLRHG---------------------------TGKLCTRFATDAPNVR-YVFTRL 2460
I+++DD + +L +TDA VR V L
Sbjct: 774 ISWFDDTANSRYYNFIYIINRRILYVLILIFICVLLPPVRLERECSTDASTVRSLVGDAL 833
Query: 2461 PVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEA 2640
+++ +I T+ L I F W + GY + + G + EEA
Sbjct: 834 ALIVQNIATVTTGLIIAFTANWILALIVLALSPFIVIQGYAQTKFLTGFSADAKAMYEEA 893
Query: 2641 GKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMY 2820
+VA+ AV IRTV S +E+ Y + P ++ GA F FS ++ +
Sbjct: 894 SQVANDAVSSIRTVASFCAEEKVMDLYQQKCDGPKKNGVRLGLLSGAGFGFSFFFLYCIN 953
Query: 2821 AAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIE 3000
F G+ + +V++VFFA++ + T++ PD KA+ +A+ +F +++
Sbjct: 954 CVCFVSGAGLIQIGKATFGEVFKVFFALTIMAIGVSQTSAMAPDSNKAKDSAASIFDILD 1013
Query: 3001 HPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSG 3177
IDS SD G ++ + G+I R+V F YP R D ++ + L I +GKTVALVG SG
Sbjct: 1014 STPKIDSSSDEGTTLQNVNGDIEFRHVSFRYPMRPDVQIFRDLCLTIPSGKTVALVGESG 1073
Query: 3178 CGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICY 3357
GKST++ ++ERFYN D G I+ID I+ +S LR+Q+ +VSQEP LF+ TI NI Y
Sbjct: 1074 SGKSTVISMIERFYNPDSGKILIDQVEIQTFKLSWLRQQMGLVSQEPILFNETIRSNIAY 1133
Query: 3358 GTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSP 3537
G T +EI+ AAK AN HNFI LP GYDT VGE+G QLSGGQKQRIAIARA+++ P
Sbjct: 1134 GKTGGATEEEIIAAAKAANAHNFISSLPQGYDTSVGERGVQLSGGQKQRIAIARAILKDP 1193
Query: 3538 SVLLLDEATSALDTESEKIVQEALD 3612
+LLLDEATSALD ESE++VQ+ALD
Sbjct: 1194 KILLLDEATSALDAESERVVQDALD 1218
Score = 323 bits (827), Expect = 3e-86
Identities = 192/561 (34%), Positives = 298/561 (52%), Gaps = 31/561 (5%)
Frame = +1
Query: 136 DLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDE 315
++ +L+ G++AA++HG FP+ ++L +F P + +
Sbjct: 682 EIPVLVLGSIAAMVHGTVFPIFGLLLSSSINMFYE-------------------PAKILK 722
Query: 316 FNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQ 495
+S + + Y+ LG+ F V F +L+ ++R ++ Q+I WFD
Sbjct: 723 KDSHF--WALIYIALGLTNFVMIPVPNYFFGIAGGKLIKRIRSMCFDKVVHQEISWFDDT 780
Query: 496 QTGN-----------------------------LTARLTDDLERVREGLGDKFALLVQMF 588
L + D VR +GD AL+VQ
Sbjct: 781 ANSRYYNFIYIINRRILYVLILIFICVLLPPVRLERECSTDASTVRSLVGDALALIVQNI 840
Query: 589 AAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEET 768
A G + F +W + L+++ +P IV+ G +K + + + Y A +A +
Sbjct: 841 ATVTTGLIIAFTANWILALIVLALSPFIVIQGYAQTKFLTGFSADAKAMYEEASQVANDA 900
Query: 769 FSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYG 948
SSIRTV S ++ +D + + ++ G+ G G GFS +Y + F G
Sbjct: 901 VSSIRTVASFCAEEKVMDLYQQKCDGPKKNGVRLGLLSGAGFGFSFFFLYCINCVCFVSG 960
Query: 949 STLI-INDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKI 1125
+ LI I TF G +F VFFA+ + + A+ +A+++ +++S PKI
Sbjct: 961 AGLIQIGKATF--GEVFKVFFALTIMAIGVSQTSAMAPDSNKAKDSAASIFDILDSTPKI 1018
Query: 1126 DPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKST 1305
D S EG + N+ GDI F+ V FRYP R D+ + + + L + +G +ALVG SG GKST
Sbjct: 1019 DSSSDEGTTLQNVNGDIEFRHVSFRYPMRPDVQIFRDLCLTIPSGKTVALVGESGSGKST 1078
Query: 1306 IVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNE-H 1482
++++++RFY+P G++LID V+++ + LR+Q+G+VSQEP+LF+ TI NI G
Sbjct: 1079 VISMIERFYNPDSGKILIDQVEIQTFKLSWLRQQMGLVSQEPILFNETIRSNIAYGKTGG 1138
Query: 1483 ATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLL 1662
AT ++++ A K ANA++FI LP GY T VGE+GVQLSGGQKQRIAIARA++K+PKILLL
Sbjct: 1139 ATEEEIIAAAKAANAHNFISSLPQGYDTSVGERGVQLSGGQKQRIAIARAILKDPKILLL 1198
Query: 1663 DEATSALDTEAEREVQGALDQ 1725
DEATSALD E+ER VQ ALD+
Sbjct: 1199 DEATSALDAESERVVQDALDR 1219
Score = 321 bits (823), Expect = 7e-86
Identities = 204/570 (35%), Positives = 300/570 (51%), Gaps = 5/570 (0%)
Frame = +1
Query: 2056 SMFKIFKFNGDKVGWXXXXXXXXXXXXS--VTPVFALVYAEIFNVY-SLPADQMQANVYF 2226
S FK+F F DK + P L++ ++ N + + D M V+
Sbjct: 17 SFFKLFSF-ADKTDVVLMTVGTIAAAGNGLTQPFMTLIFGQLINAFGTTDPDHMVREVWK 75
Query: 2227 WCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKL 2406
F+ + + V F +C GE + +R K +LRQDI ++D TG++
Sbjct: 76 VAVKFIYLAVYSCVVAFLQVSCWMVTGERQSATIRGLYLKTILRQDIGYFDT-ETNTGEV 134
Query: 2407 CTRFATDAPNVRYVF-TRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYF 2583
R + D ++ ++ + T G I FY G + G
Sbjct: 135 IGRMSGDTILIQDAMGEKVGKFTQLLCTFLGGFAIAFYKGPLLAGVLCSCIPLIVIAGAA 194
Query: 2584 EMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKH 2763
+ R EAG V Q V IRTV + ++Q Y L + T ++
Sbjct: 195 MSLIMSKMAGRGQVAYAEAGNVVEQTVGAIRTVVAFTGEKQATEKYESKLEIAYKTVVQQ 254
Query: 2764 AHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSF 2943
G ++IF Y A + G+ + ++ V V FA+ G +G T+
Sbjct: 255 GLISGFGLGTMLAVIFCSYGLAVWYGAKLIMEKGYNGGQVINVIFAVLTGGMSLGQTSPS 314
Query: 2944 IPDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTKVLQ 3120
+ R AA +F I+ ID+ SG +++ I G+I +++V+F YP R D ++
Sbjct: 315 LNAFAAGRAAAFKMFETIKRSPKIDAYDMSGSVLEDIRGDIELKDVYFRYPARPDVQIFA 374
Query: 3121 GFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVC 3300
GF+L + GKTVALVG SG GKST++ L+ERFY+ + G ++ID +++ L + +R ++
Sbjct: 375 GFSLFVPNGKTVALVGQSGSGKSTVISLIERFYDPESGQVLIDNIDLKKLQLKWIRSKIG 434
Query: 3301 IVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQ 3480
+VSQEP LF TI ENI YG + T QEI A ++AN FI LP G DT VGE GTQ
Sbjct: 435 LVSQEPVLFATTIKENIAYG-KEDATDQEIRTAIELANAAKFIDKLPQGLDTMVGEHGTQ 493
Query: 3481 LSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLS 3660
+SGGQKQR+AIARA++++P +LLLDEATSALD ESE+IVQ+AL RT +V+AHRL+
Sbjct: 494 MSGGQKQRLAIARAILKNPKILLLDEATSALDAESERIVQDALVNLMSNRTTVVVAHRLT 553
Query: 3661 TIQNSDVIAIVSEGKIVEKGTHDELIRKSE 3750
TI+ +DVIA+V +GKIVEKGTHDE+I+ E
Sbjct: 554 TIRTADVIAVVHQGKIVEKGTHDEMIQDPE 583
>gi|39594939|emb|CAE70807.1| Hypothetical protein CBG17569
[Caenorhabditis briggsae]
Length = 1224
Score = 730 bits (1884), Expect = 0.0
Identities = 437/1233 (35%), Positives = 664/1233 (53%), Gaps = 11/1233 (0%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
IF T + LL + G +++ G P ++ G ++ V + N+ +N +
Sbjct: 31 IFKCTSCFEKLLFMLGIFFSLLTGLCQPFMSYTFGEVSQVLVTITNA--------INNKT 82
Query: 292 LVPISLDE----FNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKA 459
+ P L++ F ++ +++ G F +Q + + + +++R+ Y+
Sbjct: 83 IDPADLEKAYEVFERDMNSVILHFFFCGCAYFTFGSLQFSIMKFVGDNTTYRVRKQYISR 142
Query: 460 ILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSM 639
+LR+ ++FD TG+L+ L D+LER RE +K AL++ F G + F+ W +
Sbjct: 143 LLRKDARYFDSMSTGHLSTILNDNLERFREVFNEKIALIIAFATDFTVGTALAFYTDWRL 202
Query: 640 TLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKREL 819
+ F+ I SG S SM T + YA AG+IA + + +TV SLNG ++E+
Sbjct: 203 ASYGIVFSLGIAFSGLINSASMMKNTDKQNAHYANAGSIAFQ-LGAYKTVCSLNGQRQEI 261
Query: 820 DRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFT 999
+R+ L+ G + G+ + + I G + + + ++G+ +I D T D G
Sbjct: 262 ERYTKELKEGEKYGLYRALFYSISRGVTYFFCNALNTVVLYFGANMIY-DGTLDTG---- 316
Query: 1000 VFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDIS 1179
TV+R N + + +G+ +++G+IS
Sbjct: 317 ------------------------------TVVRDDNEIERDEEDCEDGV---DVQGNIS 343
Query: 1180 FKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLI 1359
FKDV F YP R D VLKGIS ++K G+ IALVG+SG GKST+V LL +Y+ G +LI
Sbjct: 344 FKDVKFSYPIRPDAQVLKGISFDVKNGECIALVGASGSGKSTVVQLLLHYYNIESGNILI 403
Query: 1360 DGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFI 1539
DGV+L ++N+ LR IG+VSQEPVLF+ TI ENI+ GN AT ++ A + ANA DF+
Sbjct: 404 DGVELNKINLKKLRRVIGVVSQEPVLFNTTIEENIRFGNSEATLPEIYGALRKANAYDFV 463
Query: 1540 KRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGAL 1719
P G T VGE+G QLSGGQKQRIAIAR LV+NPKILLLDEATSALD E+E VQ AL
Sbjct: 464 CAFPKGIKTIVGERGTQLSGGQKQRIAIARTLVRNPKILLLDEATSALDNESEHVVQKAL 523
Query: 1720 DQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXX 1899
+ A GRTTI+VAHRLSTIRN ++I V + G IVE G+H+EL+SKQG + D+
Sbjct: 524 ENASQGRTTIVVAHRLSTIRNANKIIVMQKGEIVEVGNHDELISKQGAYNDLVQAQLLNS 583
Query: 1900 XXXE------AGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKAPPTSM 2061
+ + +S HS+ + +L +E+ + A +++
Sbjct: 584 HDDHNELPPLTARQLSHELSP-LHSYSFQRSTSTDAGVHDDDMERLLDELTQEGAKKSNL 642
Query: 2062 FKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANVYFWCGMF 2241
+I K P+ A + + Y++ + + +FW F
Sbjct: 643 REIVKMCRPDYCILFLAVFGSAIQGISYPILAQLIVRTYQGYAMHGEDILTYGHFWALSF 702
Query: 2242 VLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFA 2421
+ + + + + G+ E L+ +LR ++FK++L AFYDD +H KL R
Sbjct: 703 MFLAVFRPLTLYLQYYYFGKVAEKLSTRLRVKSFKHMLSLPSAFYDDPKHSATKLSNRLN 762
Query: 2422 TDAPNVRY-VFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMR 2598
TD+ NV+ V RL V+ ++V I A+ Y W+ + Y
Sbjct: 763 TDSSNVKAAVDDRLGCVIMTLVAISIAVITAANYCWKMTLEVLMFFPLLYLAEYCYEAAT 822
Query: 2599 FGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYG 2778
D+ E + + A +A+E++RTV +LN +++ + +L++ N+ K A G
Sbjct: 823 ENAIQEDSIAFENSNRTAIEALENVRTVRALNLEDKVMSSITNHLQKIHNSYFKRAIIQG 882
Query: 2779 AVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVV 2958
A S S F+Y+ +F G ++ ++P++ Y V +S M G+ +++PD
Sbjct: 883 AANGLSMSCFLFVYSISFKFGVYLALRKEVEPMNTYLVLMTLSMTANMAGSAAAYLPDYK 942
Query: 2959 KARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDI 3138
KA AA L+F + +P + S G G I N+ F+Y R D +L G L +
Sbjct: 943 KAVHAAGLIFNMFTYPATMPYDSSDGRKNIEKGEIVGENLQFHYDQRPDRMILNGVNLKV 1002
Query: 3139 KAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEP 3318
+ GKT+ALVG SGCGKSTI+ LLERFY+ G I ID +N+ ++N+ LR + +VSQEP
Sbjct: 1003 EPGKTLALVGPSGCGKSTIISLLERFYHVTNGEIKIDRENVEDINLHHLRANIALVSQEP 1062
Query: 3319 TLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQK 3498
TLF+C+I EN+ YG R V EI +A + AN +F+ P G DT VGE+G QLSGGQK
Sbjct: 1063 TLFNCSIRENLLYGLTRQVPQLEIEKALQTANAFHFVYQFPQGLDTIVGERGAQLSGGQK 1122
Query: 3499 QRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSD 3678
QRIAIARA++R+P VLLLDEATSALD++SEK+VQ ALD A + + +V+AHRLST+ N+D
Sbjct: 1123 QRIAIARAILRNPKVLLLDEATSALDSDSEKVVQNALDTASERLSTVVVAHRLSTVVNAD 1182
Query: 3679 VIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQ 3777
IA++ GK+ E+GTH+EL+R +Y + Q
Sbjct: 1183 SIAVLKNGKVAEQGTHEELLRLRSVYWGLVQKQ 1215
>gi|6671365|gb|AAF23176.1| P-glycoprotein [Gossypium hirsutum]
Length = 1249
Score = 729 bits (1882), Expect = 0.0
Identities = 428/1232 (34%), Positives = 674/1232 (53%), Gaps = 16/1232 (1%)
Frame = +1
Query: 91 VKLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGV 270
+KL ++ FY D +L+ G++ A +HGA P+ I G +
Sbjct: 31 LKLFSFADFY-----DHVLMGLGSLGACVHGASVPVFFIFFGKL---------------- 69
Query: 271 DNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNY 450
+N G+ + E + +V KY + ++ L V + F+S++++AC+ ER K+R Y
Sbjct: 70 --INIIGMAYLFPKEASHKVAKYSLDFVYLSVAILFSSWIEVACWMHTGERQAAKMRMAY 127
Query: 451 LKAILRQQIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFY 627
LK++L Q I FD + TG + + +T D+ V++ L +K + + F+AG+ +GF
Sbjct: 128 LKSMLNQDISLFDTEASTGEVISAITSDIIVVQDALSEKVGNFMHYISRFIAGFSIGFAR 187
Query: 628 SWSMTLVMMGFAPLIVLSG---AKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSL 798
W ++LV + PLI L+G A ++ + R R +Y AG IAEE ++RTV +
Sbjct: 188 VWQISLVTLSIVPLIALAGGIYAYVATGLIARVR---NSYVKAGEIAEEVIGNVRTVQAF 244
Query: 799 NGHKREL----DRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIIN 966
G +R + D N G++ G+ K G+G+G + ++ S+AL W+ S ++++
Sbjct: 245 AGEERAVKSYKDALMNTYTYGKKAGLTK----GLGLGSLHCVLFVSWALLVWFTS-IVVH 299
Query: 967 DPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEG 1146
+ G FT V+ SLG A P +++F AR AA + +I + S G
Sbjct: 300 KNIANGGDSFTTMLNVVISGLSLGQAAPDISAFIRARAAAYPIFEMIERNTVSKTSSKTG 359
Query: 1147 ILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQR 1326
+ ++G+I K+V F YPSR D+ + L + G +ALVG SG GKST+++L++R
Sbjct: 360 RKLSKVEGNIELKNVSFSYPSRPDVVIFDRFCLNIPTGKIVALVGGSGSGKSTVISLIER 419
Query: 1327 FYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVE 1506
FY+P G +L+DG +++ +++ LR+QIG+V+QEP LF TI ENI G + AT D++
Sbjct: 420 FYEPLAGEILLDGNNIKGLDLKWLRQQIGLVNQEPALFATTIRENILYGKDDATVDEITR 479
Query: 1507 ACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALD 1686
A K++ A FI LPD + T+VGE+G+QLSGGQKQRIAI+RA+VKNP ILLLDEATSALD
Sbjct: 480 AAKLSEAIAFINNLPDRFETQVGERGIQLSGGQKQRIAISRAIVKNPPILLLDEATSALD 539
Query: 1687 TEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIF 1866
E+E+ VQ ALD+ GRTT++VAHRLSTIRN D I V + G IVE+G+H+EL+S
Sbjct: 540 AESEKSVQEALDRVMVGRTTVVVAHRLSTIRNADVIAVVQNGKIVETGTHDELISNPNST 599
Query: 1867 YDMTXXXXXXX---XXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXX---XXIHQLAEE 2028
Y G + +S S L A+
Sbjct: 600 YSSLVQHQETSPLQRYPSQGPTLSRPLSVSYSRELSRTRTSFGASFRSERDSVSRAGADG 659
Query: 2029 VEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQM 2208
++ K P S +++ G + + P+FAL ++ Y + +
Sbjct: 660 IDAGKQPYVSPGRLYSMIGPDWYYGFFGTVTALIAGAQMPLFALGVSQALVAYYMDWETT 719
Query: 2209 QANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLR 2388
V +F + + C G GE LT+++R F +L+ +I ++DDL
Sbjct: 720 CHEVKKIAILFCCASVITVIVHAIEHLCFGIMGERLTLRVREGMFSAILKNEIGWFDDLN 779
Query: 2389 HGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXX 2565
+ + L +R TDA +R V R +++ ++ + A I F W+
Sbjct: 780 NASSMLASRLETDATFLRGVVVDRTSILIQNVGLVIAAFIIAFILNWRITLIILATFPLI 839
Query: 2566 XMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPF 2745
G E G ++ +A +A +AV ++RTV + +E+ Y L EP
Sbjct: 840 ISGHISEKLFMQGYGGNLSKAYLKANMIAGEAVSNMRTVAAFCAEEKILDLYARELIEPS 899
Query: 2746 NTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMI 2925
+ K G + SQ IF Y A + GS+ + ++ V + F + +
Sbjct: 900 ERSFKRGQIAGIFYGISQFFIFSSYGLALWYGSVLMGKELASFKSVMKSFMVLIVTALAM 959
Query: 2926 GNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRK 3102
G T + +PD++K + +F +++ T + + D+G + + G I ++ V F+YP+R
Sbjct: 960 GETLALVPDLLKGNQMVASVFEIMDRKTQV--VGDAGEELTNVEGTIELKGVHFSYPSRP 1017
Query: 3103 DTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISS 3282
D + + F L +++GK++ALVG SG GKS+++ L+ RFY+ G +MIDG +++ L + S
Sbjct: 1018 DVVIFKDFDLKVRSGKSMALVGQSGSGKSSVLALILRFYDPTSGKVMIDGRDVKKLKLKS 1077
Query: 3283 LREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHV 3462
LR+ + +V QEP LF +I ENI YG + E+VEAAK+AN H+FI LP+GY T V
Sbjct: 1078 LRKHIGLVQQEPALFATSIYENILYG-KEGASESEVVEAAKLANAHSFISSLPEGYSTKV 1136
Query: 3463 GEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLV 3642
GE+G QLSGGQKQR+AIARA++++P +LLLDEATSALD ESE++VQ+ALD + RT ++
Sbjct: 1137 GERGVQLSGGQKQRVAIARAVLKNPEILLLDEATSALDVESERVVQQALDRLMRNRTTVM 1196
Query: 3643 IAHRLSTIQNSDVIAIVSEGKIVEKGTHDELI 3738
+AHRLSTI+N+D I+++ G+I+E+GTH LI
Sbjct: 1197 VAHRLSTIKNADRISVIQGGRIIEQGTHSSLI 1228
Score = 366 bits (940), Expect = 2e-99
Identities = 220/587 (37%), Positives = 326/587 (55%), Gaps = 4/587 (0%)
Frame = +1
Query: 109 GIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPE 288
G Y G D GTV A+I GA PL F +GV +
Sbjct: 671 GRLYSMIGPDWYYGFFGTVTALIAGAQMPL-------------------FALGVS----Q 707
Query: 289 GLVPISLDEFNS--EVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAI 462
LV +D + EV K I + V+ ++ CF ERL ++R+ AI
Sbjct: 708 ALVAYYMDWETTCHEVKKIAILFCCASVITVIVHAIEHLCFGIMGERLTLRVREGMFSAI 767
Query: 463 LRQQIQWFDKQQTGN--LTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWS 636
L+ +I WFD + L +RL D +R + D+ ++L+Q +A + + F +W
Sbjct: 768 LKNEIGWFDDLNNASSMLASRLETDATFLRGVVVDRTSILIQNVGLVIAAFIIAFILNWR 827
Query: 637 MTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRE 816
+TL+++ PLI+ M + Y A IA E S++RTV + ++
Sbjct: 828 ITLIILATFPLIISGHISEKLFMQGYGGNLSKAYLKANMIAGEAVSNMRTVAAFCAEEKI 887
Query: 817 LDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIF 996
LD + L + + GI G S ++SSY LA WYGS L+ + + ++
Sbjct: 888 LDLYARELIEPSERSFKRGQIAGIFYGISQFFIFSSYGLALWYGSVLMGKELASFKSVMK 947
Query: 997 TVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDI 1176
+ F ++ + ++G L + ++V +++ ++ G + N++G I
Sbjct: 948 S-FMVLIVTALAMGETLALVPDLLKGNQMVASVFEIMDRKTQV--VGDAGEELTNVEGTI 1004
Query: 1177 SFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVL 1356
K VHF YPSR D+ + K L++++G +ALVG SG GKS+++ L+ RFYDPT G+V+
Sbjct: 1005 ELKGVHFSYPSRPDVVIFKDFDLKVRSGKSMALVGQSGSGKSSVLALILRFYDPTSGKVM 1064
Query: 1357 IDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDF 1536
IDG D++++ + SLR+ IG+V QEP LF +IYENI G E A+ +VVEA K+ANA+ F
Sbjct: 1065 IDGRDVKKLKLKSLRKHIGLVQQEPALFATSIYENILYGKEGASESEVVEAAKLANAHSF 1124
Query: 1537 IKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGA 1716
I LP+GY T+VGE+GVQLSGGQKQR+AIARA++KNP+ILLLDEATSALD E+ER VQ A
Sbjct: 1125 ISSLPEGYSTKVGERGVQLSGGQKQRVAIARAVLKNPEILLLDEATSALDVESERVVQQA 1184
Query: 1717 LDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQ 1857
LD+ RTT++VAHRLSTI+N DRI V + G I+E G+H L+ +
Sbjct: 1185 LDRLMRNRTTVMVAHRLSTIKNADRISVIQGGRIIEQGTHSSLIENR 1231
>gi|15232978|ref|NP_189480.1| P-glycoprotein, putative [Arabidopsis
thaliana]
gi|9294574|dbj|BAB02855.1| multidrug resistance p-glycoprotein; ABC
transporter-like protein [Arabidopsis thaliana]
Length = 1225
Score = 728 bits (1880), Expect = 0.0
Identities = 438/1218 (35%), Positives = 669/1218 (53%), Gaps = 7/1218 (0%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
IF + GVD +L+ G + AV G P++ + + +N G
Sbjct: 11 IFMHADGVDWMLMALGLIGAVGDGFITPIIFFICSKL------------------LNNVG 52
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
+ F V K + + + + +++ C+ ER K+R+ YLKA+LRQ
Sbjct: 53 GSSFDDETFMQTVAKNAVALVYVACASWVICFIEGYCWTRTGERQAAKMREKYLKAVLRQ 112
Query: 472 QIQWFDKQ--QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTL 645
+ +FD T ++ ++ D +++ L +K + +AF+A Y VGF W +T+
Sbjct: 113 DVGYFDLHVTSTSDVITSVSSDSLVIQDFLSEKLPNFLMNTSAFVASYIVGFLLLWRLTI 172
Query: 646 VMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDR 825
V F L+++ G +++ + +E Y AG+IAE+ SS+RTV++ K+ +++
Sbjct: 173 VGFPFIILLLIPGLMYGRALIRISMKIREEYNEAGSIAEQVISSVRTVYAFGSEKKMIEK 232
Query: 826 FYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVF 1005
F AL+ + G+ + GI +G SN Y+ + WYGS +++N + G + +V
Sbjct: 233 FSTALQGSVKLGLRQGLAKGIAIG-SNGITYAIWGFLTWYGSRMVMNHGS-KGGTVSSVI 290
Query: 1006 FAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFK 1185
V G TSLG +L +L F A +++VIN P ID +LEG +++ +G++ F
Sbjct: 291 VCVTFGGTSLGQSLSNLKYFSEAFVVGERIMKVINRVPGIDSDNLEGQILEKTRGEVEFN 350
Query: 1186 DVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDG 1365
V F YPSR + + + L + +G +ALVG SG GKST+++LLQRFYDP G +LIDG
Sbjct: 351 HVKFTYPSRPETPIFDDLCLRVPSGKTVALVGGSGSGKSTVISLLQRFYDPIAGEILIDG 410
Query: 1366 VDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKR 1545
+ + ++ V LR Q+G+VSQEPVLF +I ENI G E A+ D+VVEA K +NA+ FI +
Sbjct: 411 LPINKLQVKWLRSQMGLVSQEPVLFATSIKENILFGKEDASMDEVVEAAKASNAHSFISQ 470
Query: 1546 LPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQ 1725
P+ Y T+VGE+GVQLSGGQKQRIAIARA++K+P ILLLDEATSALD+E+ER VQ ALD
Sbjct: 471 FPNSYQTQVGERGVQLSGGQKQRIAIARAIIKSPIILLLDEATSALDSESERVVQEALDN 530
Query: 1726 AQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXX 1905
A GRTTI++AHRLSTIRN D I V G I+E+GSHEEL+ K Y
Sbjct: 531 ASIGRTTIVIAHRLSTIRNADVICVVHNGRIIETGSHEELLEKLDGQYTSLVRLQQVDNK 590
Query: 1906 XEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAE-EVEECKAPPTSMFKIFKFN 2082
+E+ + S L + ++ K+ S ++ N
Sbjct: 591 ESDHISVEEGQASSLSKDLKYSPKEFIHSTSSNIVRDFPNLSPKDGKSLVPSFKRLMSMN 650
Query: 2083 GDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPA-DQMQANVYFWCGMFVLMGIT 2259
+ +V P+++ + +VY L + DQ++ + +FV + +
Sbjct: 651 RPEWKHALYGCLGAALFGAVQPIYSYSSGSMVSVYFLASHDQIKEKTRIYVLLFVGLALF 710
Query: 2260 FFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNV 2439
F+ + GE LT ++R +L ++ ++D + +G +C+R A DA V
Sbjct: 711 TFLSNISQHYGFAYMGEYLTKRIRERMLGKILTFEVNWFDKDENSSGAICSRLAKDANMV 770
Query: 2440 R-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIR 2616
R V R+ +++ +I + IG W+ + Y + +
Sbjct: 771 RSLVGDRMSLLVQTISAVSITCAIGLVISWRFSIVMMSVQPVIVVCFYTQRVLLKSMSRN 830
Query: 2617 DTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFS 2796
+ +E+ K+A++AV +IRT+ + + QE+ P + + + G + S
Sbjct: 831 AIKGQDESSKLAAEAVSNIRTITAFSSQERIINLLKMVQEGPRKDSARQSWLAGIMLGTS 890
Query: 2797 QSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAA 2976
QSLI + A F+ G + M + +F + G++I + D+VK A
Sbjct: 891 QSLITCVSALNFWYGGKLIADGKMMSKEFLEIFLIFASTGRVIAEAGTMTKDLVKGSDAV 950
Query: 2977 SLLFYLIEHPTPIDSLSDSGIV-KPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKT 3153
+ +F +++ T I+ + G V K + G IS NV F YPTR D + Q F++DI+ GK+
Sbjct: 951 ASVFAVLDRNTTIEPENPDGYVPKKVKGQISFSNVDFAYPTRPDVIIFQNFSIDIEDGKS 1010
Query: 3154 VALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDC 3333
A+VG SG GKSTI+ L+ERFY+ KG++ IDG +IR+ ++ SLR+ + +VSQEPTLF
Sbjct: 1011 TAIVGPSGSGKSTIISLIERFYDPLKGIVKIDGRDIRSCHLRSLRQHIALVSQEPTLFAG 1070
Query: 3334 TIGENICY-GTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIA 3510
TI ENI Y G + + EI+EAAK AN H+FI L +GYDT G++G QLSGGQKQRIA
Sbjct: 1071 TIRENIMYGGASNKIDESEIIEAAKAANAHDFITSLSNGYDTCCGDRGVQLSGGQKQRIA 1130
Query: 3511 IARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAI 3690
IARA++++PSVLLLDEATSALD++SE +VQ+AL+ GRT +VIAHRLSTIQ D IA+
Sbjct: 1131 IARAVLKNPSVLLLDEATSALDSQSESVVQDALERLMVGRTSVVIAHRLSTIQKCDTIAV 1190
Query: 3691 VSEGKIVEKGTHDELIRK 3744
+ G +VE G H L+ K
Sbjct: 1191 LENGAVVECGNHSSLLAK 1208
Score = 345 bits (885), Expect = 5e-93
Identities = 205/579 (35%), Positives = 318/579 (54%), Gaps = 6/579 (1%)
Frame = +1
Query: 157 GTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEVVK 336
G + A + GA P+ + G M +V+ A + D+ +
Sbjct: 660 GCLGAALFGAVQPIYSYSSGSMVSVYFLASH--------------------DQIKEKTRI 699
Query: 337 YCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQ--TGNL 510
Y + ++ L + F ++ Q F E L ++R+ L IL ++ WFDK + +G +
Sbjct: 700 YVLLFVGLALFTFLSNISQHYGFAYMGEYLTKRIRERMLGKILTFEVNWFDKDENSSGAI 759
Query: 511 TARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAK 690
+RL D VR +GD+ +LLVQ +A +G SW ++VMM P+IV+
Sbjct: 760 CSRLAKDANMVRSLVGDRMSLLVQTISAVSITCAIGLVISWRFSIVMMSVQPVIVVCFYT 819
Query: 691 MSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVK 870
+ + +R + + +A E S+IRT+ + + +R ++ E R+ +
Sbjct: 820 QRVLLKSMSRNAIKGQDESSKLAAEAVSNIRTITAFSSQERIINLLKMVQEGPRKDSARQ 879
Query: 871 YCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALP 1050
GI +G S + AL FWYG LI + + + +F S + A
Sbjct: 880 SWLAGIMLGTSQSLITCVSALNFWYGGKLIADGKMMSKEFL-EIFLIFASTGRVIAEAGT 938
Query: 1051 HLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVL 1230
A ++V V++ + I+P + +G + +KG ISF +V F YP+R D+ +
Sbjct: 939 MTKDLVKGSDAVASVFAVLDRNTTIEPENPDGYVPKKVKGQISFSNVDFAYPTRPDVIIF 998
Query: 1231 KGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQI 1410
+ S++++ G A+VG SG GKSTI++L++RFYDP KG V IDG D+R ++ SLR+ I
Sbjct: 999 QNFSIDIEDGKSTAIVGPSGSGKSTIISLIERFYDPLKGIVKIDGRDIRSCHLRSLRQHI 1058
Query: 1411 GIVSQEPVLFDGTIYENIKMGNEHATHDQ--VVEACKMANANDFIKRLPDGYGTRVGEKG 1584
+VSQEP LF GTI ENI G D+ ++EA K ANA+DFI L +GY T G++G
Sbjct: 1059 ALVSQEPTLFAGTIRENIMYGGASNKIDESEIIEAAKAANAHDFITSLSNGYDTCCGDRG 1118
Query: 1585 VQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHR 1764
VQLSGGQKQRIAIARA++KNP +LLLDEATSALD+++E VQ AL++ GRT++++AHR
Sbjct: 1119 VQLSGGQKQRIAIARAVLKNPSVLLLDEATSALDSQSESVVQDALERLMVGRTSVVIAHR 1178
Query: 1765 LSTIRNVDRIFVFKAGNIVESGSHEELMSK--QGIFYDM 1875
LSTI+ D I V + G +VE G+H L++K +G ++ +
Sbjct: 1179 LSTIQKCDTIAVLENGAVVECGNHSSLLAKGPKGAYFSL 1217
>gi|17569907|ref|NP_509813.1| P-GlycoProtein related (pgp-6)
[Caenorhabditis elegans]
gi|6425208|emb|CAA94220.2| Hypothetical protein T21E8.1
[Caenorhabditis elegans]
Length = 1225
Score = 728 bits (1878), Expect = 0.0
Identities = 431/1232 (34%), Positives = 664/1232 (52%), Gaps = 8/1232 (0%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F + + L + G + +++ G P ++ G ++ V + N+ + ++P
Sbjct: 31 VFKCSSCFEKFLFLLGVLFSLMTGFCQPFMSYTFGEVSQVLVTITNA---INNKTIDPAD 87
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
L + +E+ + + ++ + G F + +Q A + + +++R+ Y+ +L++
Sbjct: 88 LEK-AYEEYERGMNQVVFHFFLCGCAYFIFASLQHAIMKYVGDNTTYRVRKQYISRLLKK 146
Query: 472 QIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVM 651
Q+FD TG+L+ L D+LER RE +K AL++ F G + F+ W +
Sbjct: 147 DAQYFDSVSTGHLSTVLNDNLERFREVFNEKIALIIAFVTDFTLGTALAFYTDWRLASYG 206
Query: 652 MGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFY 831
+ F+ I SG S + T + YA AG+IA +T + +TV SLNG K E++R+
Sbjct: 207 IFFSLGIAFSGFINSAGVMKTTGKQNTHYANAGSIAFQTLGAYKTVCSLNGQKTEIERYT 266
Query: 832 NALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFA 1011
L+ G + GI + I G + S + + G+T+I +
Sbjct: 267 EELKAGEKYGIRRALMYSISRGVTYFFCNSLNTVVLYVGATMIYS--------------- 311
Query: 1012 VLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDV 1191
GT A V+ I+ + + + G+ISFK+V
Sbjct: 312 ------------------GTLETAV-----VVRDDNVIEKDETDYDVEVEVNGNISFKNV 348
Query: 1192 HFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVD 1371
F YP+R D VLKGIS +++ G+ IALVG+SG GKST+V LL +Y+ G + IDG+D
Sbjct: 349 KFSYPTRPDAQVLKGISFDVQNGECIALVGASGSGKSTVVQLLLHYYNIDSGNIFIDGMD 408
Query: 1372 LREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLP 1551
L ++N+ LR IG+VSQEPVLF+ TI ENI+ GN + + ++ A + ANA DF+ P
Sbjct: 409 LNDMNIKRLRRVIGVVSQEPVLFNTTIEENIRFGNPNVSLPEIYGALRKANAYDFVCSFP 468
Query: 1552 DGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQ 1731
G T VGE+G QLSGGQKQRIAIAR LV+NPKILLLDEATSALD E+E+ VQ AL+ A
Sbjct: 469 KGIKTIVGERGTQLSGGQKQRIAIARTLVRNPKILLLDEATSALDNESEQVVQKALENAS 528
Query: 1732 AGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXXE 1911
GRTTI+VAHRLSTIRN +I V + G IVE G+H+EL++K+G++ D+
Sbjct: 529 QGRTTIVVAHRLSTIRNASKIIVMQKGEIVEVGNHDELIAKRGVYNDLVQAQLLESHDDH 588
Query: 1912 ------AGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKAPPTSMFKIF 2073
A + + +S HS+ + ++ +E+ + A +++ +I
Sbjct: 589 EELPPLAARQLSQELSP-LHSYAIQRSTSNDAGVHDDDMERILDELSKEGAKKSNLREIV 647
Query: 2074 KFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANVYFWCGMFVLMG 2253
K + P+ A + + +++ + M + W F+ +
Sbjct: 648 KQCRPDYCFLFIAVFGSAIQGVSYPILAQLIVRTYEGFAMIGEDMLYYSHLWALSFMFLA 707
Query: 2254 ITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAP 2433
+ + + G+ E L+ +LR ++F ++L AFYDD H +L R TD+
Sbjct: 708 VFRPLTLYCQYYYFGKVSEQLSTRLRIKSFSHMLSLPCAFYDDPNHSATRLSNRLNTDSS 767
Query: 2434 NVRY-VFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGY-FEMQMRFGK 2607
NV+ V RL V+ ++V I A+ Y W+ + Y +E
Sbjct: 768 NVKAAVDDRLGCVIMTVVAISIAITTASLYCWKMTLEVLMFFPLLYLAEYCYEAATETAI 827
Query: 2608 QIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVF 2787
Q DT E + + A +A+E++RTV +LN +++ E+L++ + K A GA
Sbjct: 828 Q-EDTIAFENSNRTAIEALENVRTVRALNLEDKIMSLISEHLQKIHKSYFKRAIIQGAAN 886
Query: 2788 AFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKAR 2967
S S F+Y+ +F G+ ++ + P+D Y V +S M G+ +++PD KA
Sbjct: 887 GLSLSCFLFVYSVSFKFGTYLALRKEVAPMDTYLVLMTLSMTANMAGSAAAYLPDYKKAV 946
Query: 2968 LAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAG 3147
AA L+F+L +P + S G G I NV F+Y R D +L G L + G
Sbjct: 947 HAAGLIFHLFTYPATMPFSSSDGKKNIEKGEIIGENVQFHYDQRPDRMILNGVNLKVDPG 1006
Query: 3148 KTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLF 3327
KT+ALVG SGCGKSTI+ LLERFY+ G + ID +N+ ++N++ LR + +VSQEPTLF
Sbjct: 1007 KTLALVGPSGCGKSTIISLLERFYHAVDGEVKIDSENVEDINLNHLRSNLALVSQEPTLF 1066
Query: 3328 DCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRI 3507
+C+I EN+ YG R+V E+ +A + AN NF+ P G DT VGE+G QLSGGQKQRI
Sbjct: 1067 NCSIRENLLYGLTRSVPQLELEKALQTANAFNFVFQFPQGLDTLVGERGAQLSGGQKQRI 1126
Query: 3508 AIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIA 3687
AIARA++R+P VLLLDEATSALD++SEK+VQ ALD A + + +V+AHRLST+ N+D IA
Sbjct: 1127 AIARAILRNPKVLLLDEATSALDSDSEKVVQNALDTASERLSTVVVAHRLSTVVNADSIA 1186
Query: 3688 IVSEGKIVEKGTHDELIRKSEIYQKFCETQRI 3783
++ GK+ E+GTH+EL+RK IY + + Q I
Sbjct: 1187 VLKNGKVAEQGTHEELLRKRSIYWRLVQKQGI 1218
>gi|9294577|dbj|BAB02858.1| multidrug resistance p-glycoprotein; ABC
transporter-like protein [Arabidopsis thaliana]
Length = 1262
Score = 726 bits (1874), Expect = 0.0
Identities = 451/1242 (36%), Positives = 683/1242 (54%), Gaps = 19/1242 (1%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
IF + VDL+L+ G + AV G P++ + G + +N G
Sbjct: 43 IFMHANSVDLVLMGLGLIGAVGDGFITPIIFFITGLL------------------LNDIG 84
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
F ++K + L + +V+ C+ ER ++R+ YL+A+LRQ
Sbjct: 85 DSSFGDKTFMHAIMKNAVALLYVAGASLVICFVEGYCWTRTGERQASRMREKYLRAVLRQ 144
Query: 472 QIQWFDKQ--QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTL 645
+ +FD T ++ ++ D +++ L +K + +AF+A Y VGF W +T+
Sbjct: 145 DVGYFDLHVTSTSDVITSVSSDTLVIQDVLSEKLPNFLMSASAFVASYIVGFIMLWRLTI 204
Query: 646 VMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDR 825
V F L+++ G +++ +R +E Y AG+IAE+ S +RTV++ ++ + +
Sbjct: 205 VGFPFFILLLIPGLMCGRALINISRKIREEYNEAGSIAEQAISLVRTVYAFGSERKMISK 264
Query: 826 FYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVF 1005
F ALE + G+ + GI +G SN Y+ + WYGS +++ G IF V
Sbjct: 265 FSAALEGSVKLGLRQGIAKGIAIG-SNGVTYAIWGFMTWYGSRMVMYHGA-KGGTIFAVI 322
Query: 1006 FAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFK 1185
+ G TSLG L +L F A A ++ VI P ID + G +++N+KG++ FK
Sbjct: 323 ICITYGGTSLGRGLSNLKYFSEAVVAGERIIEVIKRVPDIDSDNPRGQVLENIKGEVQFK 382
Query: 1186 DVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDG 1365
V F Y SR + + + L + +G +ALVG SG GKST+++LLQRFYDP G +LIDG
Sbjct: 383 HVKFMYSSRPETPIFDDLCLRIPSGKSVALVGGSGSGKSTVISLLQRFYDPIVGEILIDG 442
Query: 1366 VDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKR 1545
V ++++ V LR Q+G+VSQEP LF +I ENI G E A+ D+VVEA K +NA+DFI +
Sbjct: 443 VSIKKLQVKWLRSQMGLVSQEPALFATSIEENILFGKEDASFDEVVEAAKSSNAHDFISQ 502
Query: 1546 LPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQ 1725
P GY T+VGE+GVQ+SGGQKQRI+IARA++K+P +LLLDEATSALD+E+ER VQ ALD
Sbjct: 503 FPLGYKTQVGERGVQMSGGQKQRISIARAIIKSPTLLLLDEATSALDSESERVVQEALDN 562
Query: 1726 AQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXX 1905
A GRTTI++AHRLSTIRNVD I VFK G IVE+GSHEELM Y +
Sbjct: 563 ATIGRTTIVIAHRLSTIRNVDVICVFKNGQIVETGSHEELMENVDGQY-TSLVRLQIMEN 621
Query: 1906 XEAGKDIEDTISESAHSHL---------XXXXXXXXXXXXXXXIHQLAEEVEECKAPPTS 2058
E+ ++ ++ E S+ LA + + K P S
Sbjct: 622 EESNDNVSVSMREGQFSNFNKDVKYSSRLSIQSRSSLFATSSIDTNLAGSIPKDKKP--S 679
Query: 2059 MFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPA-DQMQANVYFWCG 2235
++ N + ++ P++A + +VY L + D+M+ +
Sbjct: 680 FKRLMAMNKPEWKHALYGCLSAVLYGALHPIYAYASGSMVSVYFLTSHDEMKEKTRIYVL 739
Query: 2236 MFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTR 2415
+FV + + F+ GE LT ++R LL +++++D+ + +G +C+R
Sbjct: 740 LFVGLAVLCFLISIIQQYSFAYMGEYLTKRIRENILSKLLTFEVSWFDEDENSSGSICSR 799
Query: 2416 FATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQ 2592
A DA VR V R+ +++ +I + A +G W+ + G F Q
Sbjct: 800 LAKDANVVRSLVGERVSLLVQTISAVSVACTLGLAISWK--LSIVMIAIQPVVVGCFYTQ 857
Query: 2593 MRFGKQI--RDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHA 2766
K I + + +E+ K+A++AV +IRT+ + + QE+ P N++ +
Sbjct: 858 RIVLKSISKKAIKAQDESSKLAAEAVSNIRTITAFSSQERILKLLKMVQEGPQRENIRQS 917
Query: 2767 HTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFI 2946
G V A S+SL+ A ++ G+ + + + +F G++I + +
Sbjct: 918 WLAGIVLATSRSLMTCTSALNYWYGARLIIDGKITSKAFFELFILFVSTGRVIADAGAMT 977
Query: 2947 PDVVKARLAASLLFYLIEHPTPIDSLSDSGIV-KPITGNISIRNVFFNYPTRKDTKVLQG 3123
D+ K A +F +++ T I+ G V + I G I NV F YPTR D + +
Sbjct: 978 MDLAKGSDAVGSVFAVLDRYTNIEPEKPDGFVPQNIKGQIKFVNVDFAYPTRPDVIIFKN 1037
Query: 3124 FTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCI 3303
F++DI GK+ A+VG SG GKSTI+GL+ERFY+ KG++ IDG +IR+ ++ SLR+ + +
Sbjct: 1038 FSIDIDEGKSTAIVGPSGSGKSTIIGLIERFYDPLKGIVKIDGRDIRSYHLRSLRQHIGL 1097
Query: 3304 VSQEPTLFDCTIGENICY-GTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQ 3480
VSQEP LF TI ENI Y G + + EI+EAAK AN H+FI+ L DGYDT+ G++G Q
Sbjct: 1098 VSQEPILFAGTIRENIMYGGASDKIDESEIIEAAKAANAHDFIVTLSDGYDTYCGDRGVQ 1157
Query: 3481 LSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLS 3660
LSGGQKQRIAIARA++++PSVLLLDEATSALD +SE++VQ+AL GRT +VIAHRLS
Sbjct: 1158 LSGGQKQRIAIARAVLKNPSVLLLDEATSALDNQSERMVQDALGRLMVGRTSVVIAHRLS 1217
Query: 3661 TIQNSDVIAIVSEGKIVEKGTHDELIRK--SEIYQKFCETQR 3780
TIQN D I ++ +GK+VE GTH L+ K + +Y QR
Sbjct: 1218 TIQNCDTITVLDKGKVVECGTHSSLLAKGPTGVYFSLVSLQR 1259
>gi|15220188|ref|NP_172538.1| P-glycoprotein, putative [Arabidopsis
thaliana]
Length = 1227
Score = 726 bits (1873), Expect = 0.0
Identities = 433/1241 (34%), Positives = 685/1241 (54%), Gaps = 11/1241 (0%)
Frame = +1
Query: 91 VKLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGV 270
+KL ++ FY D +L+ G++ A IHGA P+ I G +
Sbjct: 27 LKLFSFADFY-----DCVLMALGSIGACIHGASVPVFFIFFGKL---------------- 65
Query: 271 DNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNY 450
+N GL + E + +V KY + ++ L V++ F+S++++AC+ ER K+R+ Y
Sbjct: 66 --INIIGLAYLFPQEASHKVAKYSLDFVYLSVVILFSSWLEVACWMHTGERQAAKIRKAY 123
Query: 451 LKAILRQQIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFY 627
L+++L Q I FD + TG + + +T ++ V++ + +K + + F+AG+ +GF
Sbjct: 124 LRSMLSQDISLFDTEISTGEVISAITSEILVVQDAISEKVGNFMHFISRFIAGFAIGFAS 183
Query: 628 SWSMTLVMMGFAPLIVLSG---AKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSL 798
W ++LV + P I L+G A +S + R R ++Y A IAEE ++RTV +
Sbjct: 184 VWQISLVTLSIVPFIALAGGIYAFVSSGLIVRVR---KSYVKANEIAEEVIGNVRTVQAF 240
Query: 799 NGHKRELDRFYNALE----VGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIIN 966
G ++ + + AL GR+ G+ K G+G+G + ++ S+AL W+ S ++++
Sbjct: 241 TGEEKAVSSYQGALRNTYNYGRKAGLAK----GLGLGSLHFVLFLSWALLIWFTS-IVVH 295
Query: 967 DPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEG 1146
+ G FT V+ SLG A P +++F A AA + ++I + + G
Sbjct: 296 KGIANGGESFTTMLNVVIAGLSLGQAAPDISTFMRASAAAYPIFQMIERNTE----DKTG 351
Query: 1147 ILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQR 1326
+ N+ GDI FKDV F YPSR D+ + ++ + AG +ALVG SG GKST+++L++R
Sbjct: 352 RKLGNVNGDILFKDVTFTYPSRPDVVIFDKLNFVIPAGKVVALVGGSGSGKSTMISLIER 411
Query: 1327 FYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVE 1506
FY+PT G V++DG D+R +++ LR IG+V+QEPVLF TI ENI G + AT +++
Sbjct: 412 FYEPTDGAVMLDGNDIRYLDLKWLRGHIGLVNQEPVLFATTIRENIMYGKDDATSEEITN 471
Query: 1507 ACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALD 1686
A K++ A FI LP+G+ T+VGE+G+QLSGGQKQRI+I+RA+VKNP ILLLDEATSALD
Sbjct: 472 AAKLSEAISFINNLPEGFETQVGERGIQLSGGQKQRISISRAIVKNPSILLLDEATSALD 531
Query: 1687 TEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIF 1866
E+E+ VQ ALD+ GRTT++VAHRLST+RN D I V G I+ESGSH+EL+S
Sbjct: 532 AESEKIVQEALDRVMVGRTTVVVAHRLSTVRNADIIAVVGGGKIIESGSHDELISNPDGA 591
Query: 1867 YDMTXXXXXXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKA 2046
Y A ++ T S + IHQ + + K
Sbjct: 592 Y-----SSLLRIQEAASPNLNHTPSLPVST---KPLPELPITETTSSIHQSVNQPDTTKQ 643
Query: 2047 PPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANVYF 2226
++ +++ + S P+FAL A+ Y + + Q V
Sbjct: 644 AKVTVGRLYSMIRPDWKYGLCGTLGSFIAGSQMPLFALGIAQALVSYYMDWETTQNEVKR 703
Query: 2227 WCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKL 2406
+F + + G GE LT+++R + F +LR +I ++D + + + L
Sbjct: 704 ISILFCCGSVITVIVHTIEHTTFGIMGERLTLRVRQKMFSAILRNEIGWFDKVDNTSSML 763
Query: 2407 CTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYF 2583
+R +DA +R V R ++L ++ + A I F W+ G
Sbjct: 764 ASRLESDATLLRTIVVDRSTILLENLGLVVTAFIISFILNWRLTLVVLATYPLIISGHIS 823
Query: 2584 EMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKH 2763
E G ++ +A +A +++ +IRTV + +E+ Y + L EP + +
Sbjct: 824 EKIFMQGYGGNLSKAYLKANMLAGESISNIRTVVAFCAEEKVLDLYSKELLEPSERSFRR 883
Query: 2764 AHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSF 2943
G ++ SQ IF Y A + GSI + + V + F + ++G +
Sbjct: 884 GQMAGILYGVSQFFIFSSYGLALWYGSILMEKGLSSFESVMKTFMVLIVTALVMGEVLAL 943
Query: 2944 IPDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTKVLQ 3120
PD++K +F L++ T + + D+G + + G I ++ V F+YP+R D +
Sbjct: 944 APDLLKGNQMVVSVFELLDRRTQV--VGDTGEELSNVEGTIELKGVHFSYPSRPDVTIFS 1001
Query: 3121 GFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVC 3300
F L + +GK++ALVG SG GKS+++ L+ RFY+ G+IMIDG +I+ L + SLR +
Sbjct: 1002 DFNLLVPSGKSMALVGQSGSGKSSVLSLVLRFYDPTAGIIMIDGQDIKKLKLKSLRRHIG 1061
Query: 3301 IVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQ 3480
+V QEP LF TI ENI YG + E++EAAK+AN H+FI LP+GY T VGE+G Q
Sbjct: 1062 LVQQEPALFATTIYENILYG-KEGASESEVMEAAKLANAHSFISSLPEGYSTKVGERGIQ 1120
Query: 3481 LSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLS 3660
+SGGQ+QRIAIARA++++P +LLLDEATSALD ESE++VQ+ALD + RT +V+AHRLS
Sbjct: 1121 MSGGQRQRIAIARAVLKNPEILLLDEATSALDVESERVVQQALDRLMRDRTTVVVAHRLS 1180
Query: 3661 TIQNSDVIAIVSEGKIVEKGTHDELI-RKSEIYQKFCETQR 3780
TI+NSD+I+++ +GKI+E+G+H+ L+ K+ Y K Q+
Sbjct: 1181 TIKNSDMISVIQDGKIIEQGSHNILVENKNGPYSKLISLQQ 1221
Score = 311 bits (796), Expect = 1e-82
Identities = 201/583 (34%), Positives = 303/583 (51%), Gaps = 6/583 (1%)
Frame = +1
Query: 2008 IHQLAEEVEECKAPPTSMFKIFKFNG--DKVGWXXXXXXXXXXXXSVTPVFALVYAEIFN 2181
I +A +E K P S K+F F D V SV PVF + + ++ N
Sbjct: 9 IVDMAAAEKEKKRPSVSFLKLFSFADFYDCVLMALGSIGACIHGASV-PVFFIFFGKLIN 67
Query: 2182 VYSLP---ADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNL 2352
+ L + V + FV + + + C GE K+R +++
Sbjct: 68 IIGLAYLFPQEASHKVAKYSLDFVYLSVVILFSSWLEVACWMHTGERQAAKIRKAYLRSM 127
Query: 2353 LRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVFT-RLPVVLASIVTICGALGIGFYYGWQ 2529
L QDI+ +D TG++ + ++ V+ + ++ + I IGF WQ
Sbjct: 128 LSQDISLFDT-EISTGEVISAITSEILVVQDAISEKVGNFMHFISRFIAGFAIGFASVWQ 186
Query: 2530 XXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQF 2709
+ G + G +R + +A ++A + + ++RTV + +E+
Sbjct: 187 ISLVTLSIVPFIALAGGIYAFVSSGLIVRVRKSYVKANEIAEEVIGNVRTVQAFTGEEKA 246
Query: 2710 HFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYR 2889
+Y LR +N K G ++F +A + SI V++ + +
Sbjct: 247 VSSYQGALRNTYNYGRKAGLAKGLGLGSLHFVLFLSWALLIWFTSIVVHKGIANGGESFT 306
Query: 2890 VFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISI 3069
+ G +G I ++A AA +F +IE T + G V G+I
Sbjct: 307 TMLNVVIAGLSLGQAAPDISTFMRASAAAYPIFQMIERNTEDKTGRKLGNVN---GDILF 363
Query: 3070 RNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMID 3249
++V F YP+R D + I AGK VALVG SG GKST++ L+ERFY G +M+D
Sbjct: 364 KDVTFTYPSRPDVVIFDKLNFVIPAGKVVALVGGSGSGKSTMISLIERFYEPTDGAVMLD 423
Query: 3250 GDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFI 3429
G++IR L++ LR + +V+QEP LF TI ENI YG + + T +EI AAK++ +FI
Sbjct: 424 GNDIRYLDLKWLRGHIGLVNQEPVLFATTIRENIMYGKD-DATSEEITNAAKLSEAISFI 482
Query: 3430 LGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEAL 3609
LP+G++T VGE+G QLSGGQKQRI+I+RA+V++PS+LLLDEATSALD ESEKIVQEAL
Sbjct: 483 NNLPEGFETQVGERGIQLSGGQKQRISISRAIVKNPSILLLDEATSALDAESEKIVQEAL 542
Query: 3610 DAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELI 3738
D GRT +V+AHRLST++N+D+IA+V GKI+E G+HDELI
Sbjct: 543 DRVMVGRTTVVVAHRLSTVRNADIIAVVGGGKIIESGSHDELI 585
>gi|38049160|gb|AAR10387.1| P-glycoprotein 1 [Sorghum bicolor]
Length = 1402
Score = 725 bits (1872), Expect = 0.0
Identities = 435/1263 (34%), Positives = 683/1263 (53%), Gaps = 39/1263 (3%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F + G+D L++ GT+ A++HG P VFLR F VD+
Sbjct: 131 LFRFADGLDCALMLVGTLGALVHGCSLP-----------VFLRF----FADLVDSFGSHA 175
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
P D VVKY Y+LV+G ++ +S+ +I+C+ ER ++R YL A LRQ
Sbjct: 176 NDP---DTMVRLVVKYAFYFLVVGAAIWASSWAEISCWMWTGERQSTRMRIRYLDAALRQ 232
Query: 472 QIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLV 648
+ +FD +T ++ + D V++ + +K L+ A F+AG+ VGF +W + LV
Sbjct: 233 DVSFFDTDVRTSDVIYAINADAVVVQDAISEKLGNLIHYMATFVAGFVVGFTAAWQLALV 292
Query: 649 MMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRF 828
+ PLI + G + ++A + Q+ + A IAE+ + IR V + G +RE+ +
Sbjct: 293 TLAVVPLIAVIGGLSAAALAKLSSRSQDALSGASGIAEQALAQIRIVQAFVGEEREMRAY 352
Query: 829 YNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFF 1008
AL V ++ G G+G+G + ++ Y L WYG L+ T + GL F
Sbjct: 353 SAALAVAQKIGYRSGFAKGLGLGGTYFTVFCCYGLLLWYGGHLVRGHHT-NGGLAIATMF 411
Query: 1009 AVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLE---GILVDNMKGDIS 1179
+V+ G +LG + P +A+F AR AA+ + R+I+ P I E G+ ++++ G +
Sbjct: 412 SVMIGGLALGQSAPSMAAFAKARVAAAKIFRIIDHRPGISSRDGEDGGGVELESVTGRVE 471
Query: 1180 FKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLI 1359
+ V F YPSR D+ +L+G SL + AG IALVGSSG GKST+V+LL+RFYDP+ G++L+
Sbjct: 472 MRGVDFAYPSRPDVPILRGFSLSVPAGKTIALVGSSGSGKSTVVSLLERFYDPSAGQILL 531
Query: 1360 DGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMG--NEHATHDQVVEACKMANAND 1533
DG DL+ + + LR+QIG+VSQEP LF +I EN+ +G ++ AT ++ EA ++ANA+
Sbjct: 532 DGHDLKSLKLRWLRQQIGLVSQEPTLFATSIKENLLLGRDSQSATQAEMEEAARVANAHS 591
Query: 1534 FIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQG 1713
FI +LPDGY T+VGE+G+QLSGGQKQRIAIARA++KNP ILLLDEATSALD+E+E+ VQ
Sbjct: 592 FIVKLPDGYDTQVGERGLQLSGGQKQRIAIARAMLKNPAILLLDEATSALDSESEKLVQE 651
Query: 1714 ALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSK------------- 1854
ALD+ GRTT+++AHR+STIR D + V + G + E G+H+ELM+K
Sbjct: 652 ALDRFMIGRTTLVIAHRMSTIRKADVVAVLQGGPVSEMGAHDELMAKGENGTYAKFIRMQ 711
Query: 1855 ----QGIFYDMTXXXXX-XXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQ- 2016
+ F + I S S IH
Sbjct: 712 EQAHEAAFVNARRSSARPSSARNSVSSPIMTRNSSYGRSPYSRRLSDFSTSDFTLSIHDP 771
Query: 2017 ------LAEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIF 2178
+A++ +A +S ++ + N + + S + +FA + + +
Sbjct: 772 HHHHRTMADKQLAFRAGASSFLRLARMNSPEWAYALVGSLGSMVCGSFSAIFAYILSAVL 831
Query: 2179 NVYSLPADQ-MQANVYFWCGMFVLMGITFFVGFFTSANCL--GRCGESLTMKLRFEAFKN 2349
+VY P + M+ + +C ++L+G++ F + + GE+LT ++R + F
Sbjct: 832 SVYYAPDPRYMKREIAKYC--YLLIGMSSAALLFNTVQHVFWDTVGENLTKRVREKMFAA 889
Query: 2350 LLRQDIAFYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGW 2526
+LR +IA++D + + ++ R A DA NVR + R+ V++ + + A GF W
Sbjct: 890 VLRNEIAWFDADENASARVAARLALDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQW 949
Query: 2527 QXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQ 2706
+ + G A ++A +AV ++RTV + N + +
Sbjct: 950 RLALVLLAVFPLVVAATVLQKMFMKGFSGDLEAAHARATQIAGEAVANLRTVAAFNAERK 1009
Query: 2707 FHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVY 2886
+ LR P G+ + +Q L++ YA + + V
Sbjct: 1010 ITGLFEANLRGPLRRCFWKGQIAGSGYGVAQFLLYASYALGLWYAAWLVKHGVSDFSRTI 1069
Query: 2887 RVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPI--DSLSDSGIVKPITGN 3060
RVF + T + PD VK A +F I+ T + D + + + + G
Sbjct: 1070 RVFMVLMVSANGAAETLTLAPDFVKGGRAMRSVFETIDRKTEVEPDDVDAAPVPERPKGE 1129
Query: 3061 ISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMI 3240
+ +++V F+YP+R D +V + +L +AGKT+ALVG SGCGKS+++ L++RFY G +
Sbjct: 1130 VELKHVDFSYPSRPDIQVFRDLSLRARAGKTLALVGPSGCGKSSVLALVQRFYEPTSGRV 1189
Query: 3241 MIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIH 3420
++DG ++R N+ +LR V + QEP LF +I +NI YG T E+VEAA AN H
Sbjct: 1190 LLDGKDVRKYNLRALRRVVAVAPQEPFLFAASIHDNIAYG-REGATEAEVVEAATQANAH 1248
Query: 3421 NFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQ 3600
FI LP+GY T VGE+G QLSGGQ+QRIAIARALV+ +++LLDEATSALD ESE+ VQ
Sbjct: 1249 RFIAALPEGYGTQVGERGVQLSGGQRQRIAIARALVKQAAIVLLDEATSALDAESERCVQ 1308
Query: 3601 EALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIR--KSEIYQKFCET 3774
EAL+ A GRT +V+AHRL+T++ + IA++ +GK+ E+G+H L++ Y + +
Sbjct: 1309 EALERAGSGRTTIVVAHRLATVRGAHTIAVIDDGKVAEQGSHSHLLKHHPDGCYARMLQL 1368
Query: 3775 QRI 3783
QR+
Sbjct: 1369 QRL 1371
Score = 329 bits (844), Expect = 3e-88
Identities = 210/590 (35%), Positives = 312/590 (52%), Gaps = 13/590 (2%)
Frame = +1
Query: 2047 PPTSMFKIFKF-NGDKVGWXXXXXXXXXXXXSVTPVFALVYAEI---FNVYSLPADQMQA 2214
PP ++ +F+F +G PVF +A++ F ++ D M
Sbjct: 124 PPAALRDLFRFADGLDCALMLVGTLGALVHGCSLPVFLRFFADLVDSFGSHANDPDTMVR 183
Query: 2215 NVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYD-DLRH 2391
V + F+++G + + +C GE + ++R LRQD++F+D D+R
Sbjct: 184 LVVKYAFYFLVVGAAIWASSWAEISCWMWTGERQSTRMRIRYLDAALRQDVSFFDTDVR- 242
Query: 2392 GTGKLCTRFATDAPNVRYVFT-RLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXX 2568
T + DA V+ + +L ++ + T +GF WQ
Sbjct: 243 -TSDVIYAINADAVVVQDAISEKLGNLIHYMATFVAGFVVGFTAAWQLALVTLAVVPLIA 301
Query: 2569 MGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFN 2748
+ G R L A +A QA+ IR V + +E+ Y L
Sbjct: 302 VIGGLSAAALAKLSSRSQDALSGASGIAEQALAQIRIVQAFVGEEREMRAYSAALAVAQK 361
Query: 2749 TNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIG 2928
+ G + +F Y + G V F++ G +G
Sbjct: 362 IGYRSGFAKGLGLGGTYFTVFCCYGLLLWYGGHLVRGHHTNGGLAIATMFSVMIGGLALG 421
Query: 2929 NTTSFIPDVVKARLAASLLFYLIEHPTPIDSLS--DSGIVK--PITGNISIRNVFFNYPT 3096
+ + KAR+AA+ +F +I+H I S D G V+ +TG + +R V F YP+
Sbjct: 422 QSAPSMAAFAKARVAAAKIFRIIDHRPGISSRDGEDGGGVELESVTGRVEMRGVDFAYPS 481
Query: 3097 RKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNI 3276
R D +L+GF+L + AGKT+ALVG SG GKST++ LLERFY+ G I++DG ++++L +
Sbjct: 482 RPDVPILRGFSLSVPAGKTIALVGSSGSGKSTVVSLLERFYDPSAGQILLDGHDLKSLKL 541
Query: 3277 SSLREQVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYD 3453
LR+Q+ +VSQEPTLF +I EN+ G + ++ T E+ EAA++AN H+FI+ LPDGYD
Sbjct: 542 RWLRQQIGLVSQEPTLFATSIKENLLLGRDSQSATQAEMEEAARVANAHSFIVKLPDGYD 601
Query: 3454 THVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRT 3633
T VGE+G QLSGGQKQRIAIARA++++P++LLLDEATSALD+ESEK+VQEALD GRT
Sbjct: 602 TQVGERGLQLSGGQKQRIAIARAMLKNPAILLLDEATSALDSESEKLVQEALDRFMIGRT 661
Query: 3634 CLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSE--IYQKFCETQ 3777
LVIAHR+STI+ +DV+A++ G + E G HDEL+ K E Y KF Q
Sbjct: 662 TLVIAHRMSTIRKADVVAVLQGGPVSEMGAHDELMAKGENGTYAKFIRMQ 711
>gi|20466380|gb|AAM20507.1| P-glycoprotein-2 [Arabidopsis thaliana]
Length = 1233
Score = 724 bits (1869), Expect = 0.0
Identities = 430/1243 (34%), Positives = 682/1243 (54%), Gaps = 14/1243 (1%)
Frame = +1
Query: 94 KLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVD 273
K++ +F + D +L+ G+V A IHGA P+ I G +
Sbjct: 19 KVSLLKLFSFADFYDCVLMTLGSVGACIHGASVPIFFIFFGKL----------------- 61
Query: 274 NVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYL 453
+N GL + + + V KY + ++ L V + F+S++++AC+ ER K+R+ YL
Sbjct: 62 -INIIGLAYLFPKQASHRVAKYSLDFVYLSVAILFSSWLEVACWMHTGERQAAKMRRAYL 120
Query: 454 KAILRQQIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYS 630
+++L Q I FD + TG + + +T D+ V++ L +K + + F+AG+ +GF
Sbjct: 121 RSMLSQDISLFDTEASTGEVISAITSDILVVQDALSEKVGNFLHYISRFIAGFAIGFTSV 180
Query: 631 WSMTLVMMGFAPLIVLSG---AKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLN 801
W ++LV + PLI L+G A ++ + R R ++Y AG IAEE ++RTV +
Sbjct: 181 WQISLVTLSIVPLIALAGGIYAFVAIGLIARVR---KSYIKAGEIAEEVIGNVRTVQAFT 237
Query: 802 GHKRELDRFYNALE----VGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIIND 969
G +R + + ALE GR+ G+ K G+G+G + ++ S+AL W+ S ++ D
Sbjct: 238 GEERAVRLYREALENTYKYGRKAGLTK----GLGLGSMHCVLFLSWALLVWFTSVVVHKD 293
Query: 970 PTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGI 1149
D G FT V+ SLG A P +++F A+ AA + ++I + + G
Sbjct: 294 IA-DGGKSFTTMLNVVIAGLSLGQAAPDISAFVRAKAAAYPIFKMIERNTVTKTSAKSGR 352
Query: 1150 LVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRF 1329
+ + G I FKD F YPSR D+ + ++L + AG +ALVG SG GKST+++L++RF
Sbjct: 353 KLGKVDGHIQFKDATFSYPSRPDVVIFDRLNLAIPAGKIVALVGGSGSGKSTVISLIERF 412
Query: 1330 YDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEA 1509
Y+P G VL+DG ++ E+++ LR QIG+V+QEP LF TI ENI G + AT +++ A
Sbjct: 413 YEPISGAVLLDGNNISELDIKWLRGQIGLVNQEPALFATTIRENILYGKDDATAEEITRA 472
Query: 1510 CKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDT 1689
K++ A FI LP+G+ T+VGE+G+QLSGGQKQRIAI+RA+VKNP ILLLDEATSALD
Sbjct: 473 AKLSEAISFINNLPEGFETQVGERGIQLSGGQKQRIAISRAIVKNPSILLLDEATSALDA 532
Query: 1690 EAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFY 1869
E+E+ VQ ALD+ GRTT++VAHRLST+RN D I V G IVE G+HE L+S Y
Sbjct: 533 ESEKSVQEALDRVMVGRTTVVVAHRLSTVRNADIIAVVHEGKIVEFGNHENLISNPDGAY 592
Query: 1870 DMTXXXXXXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLA--EEVEECK 2043
+ + + T+S HS + + + K
Sbjct: 593 S-SLLRLQETASLQRNPSLNRTLSR-PHSIKYSRELSRTRSSFCSERESVTRPDGADPSK 650
Query: 2044 APPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANVY 2223
++ +++ + S P+FAL ++ Y D+ Q +
Sbjct: 651 KVKVTVGRLYSMIRPDWMYGVCGTICAFIAGSQMPLFALGVSQALVSYYSGWDETQKEIK 710
Query: 2224 FWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGK 2403
+F + + + C G GE LT+++R F+ +L+ +I ++D++ + +
Sbjct: 711 KIAILFCCASVITLIVYTIEHICFGTMGERLTLRVRENMFRAILKNEIGWFDEVDNASSM 770
Query: 2404 LCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGY 2580
L +R +DA ++ V R ++L ++ + + I F W+ G
Sbjct: 771 LASRLESDATLLKTIVVDRSTILLQNLGLVVTSFIIAFILNWRLTLVVLATYPLVISGHI 830
Query: 2581 FE--MQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTN 2754
E +G + L +A +A ++V +IRTV + +E+ Y L EP ++
Sbjct: 831 SEKLFMQGYGGDLNKAYL--KANMLAGESVSNIRTVAAFCAEEKILELYSRELLEPSKSS 888
Query: 2755 LKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNT 2934
+ G + SQ IF Y A + GS +++ V + F + +G T
Sbjct: 889 FRRGQIAGLFYGVSQFFIFSSYGLALWYGSTLMDKGLAGFKSVMKTFMVLIVTALAMGET 948
Query: 2935 TSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKV 3114
+ PD++K + +F +++ T I S + + G I ++ V F+YP+R D +
Sbjct: 949 LALAPDLLKGNQMVASVFEILDRKTQIVG-ETSEELNNVEGTIELKGVHFSYPSRPDVVI 1007
Query: 3115 LQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQ 3294
+ F L ++AGK++ALVG SG GKS+++ L+ RFY+ G +MI+G +I+ L++ +LR+
Sbjct: 1008 FRDFDLIVRAGKSMALVGQSGSGKSSVISLILRFYDPTAGKVMIEGKDIKKLDLKALRKH 1067
Query: 3295 VCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKG 3474
+ +V QEP LF TI ENI YG N + E+VE+A +AN H+FI LP+GY T VGE+G
Sbjct: 1068 IGLVQQEPALFATTIYENILYG-NEGASQSEVVESAMLANAHSFITSLPEGYSTKVGERG 1126
Query: 3475 TQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHR 3654
Q+SGGQ+QRIAIARA++++P++LLLDEATSALD ESE++VQ+ALD RT +V+AHR
Sbjct: 1127 VQMSGGQRQRIAIARAILKNPAILLLDEATSALDVESERVVQQALDRLMANRTTVVVAHR 1186
Query: 3655 LSTIQNSDVIAIVSEGKIVEKGTHDELI-RKSEIYQKFCETQR 3780
LSTI+N+D I+++ GKIVE+G+H +L+ KS Y K Q+
Sbjct: 1187 LSTIKNADTISVLHGGKIVEQGSHRKLVLNKSGPYFKLISLQQ 1229
Score = 373 bits (957), Expect = e-101
Identities = 220/603 (36%), Positives = 340/603 (55%), Gaps = 8/603 (1%)
Frame = +1
Query: 91 VKLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGV 270
VK+T G Y D + + GT+ A I G+ PL A+ G++ + +
Sbjct: 652 VKVT-VGRLYSMIRPDWMYGVCGTICAFIAGSQMPLFAL---GVSQALVSYYSG------ 701
Query: 271 DNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNY 450
DE E+ K I + V+ ++ CF + ERL ++R+N
Sbjct: 702 ------------WDETQKEIKKIAILFCCASVITLIVYTIEHICFGTMGERLTLRVRENM 749
Query: 451 LKAILRQQIQWFDKQQTGN--LTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFF 624
+AIL+ +I WFD+ + L +RL D ++ + D+ +L+Q + + + F
Sbjct: 750 FRAILKNEIGWFDEVDNASSMLASRLESDATLLKTIVVDRSTILLQNLGLVVTSFIIAFI 809
Query: 625 YSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNG 804
+W +TLV++ PL++ M + Y A +A E+ S+IRTV +
Sbjct: 810 LNWRLTLVVLATYPLVISGHISEKLFMQGYGGDLNKAYLKANMLAGESVSNIRTVAAFCA 869
Query: 805 HKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDR 984
++ L+ + L ++ + G+ G S ++SSY LA WYGSTL+ D+
Sbjct: 870 EEKILELYSRELLEPSKSSFRRGQIAGLFYGVSQFFIFSSYGLALWYGSTLM------DK 923
Query: 985 GL-----IFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGI 1149
GL + F ++ + ++G L ++V +++ +I + E +
Sbjct: 924 GLAGFKSVMKTFMVLIVTALAMGETLALAPDLLKGNQMVASVFEILDRKTQIVGETSEEL 983
Query: 1150 LVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRF 1329
+N++G I K VHF YPSR D+ + + L ++AG +ALVG SG GKS++++L+ RF
Sbjct: 984 --NNVEGTIELKGVHFSYPSRPDVVIFRDFDLIVRAGKSMALVGQSGSGKSSVISLILRF 1041
Query: 1330 YDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEA 1509
YDPT G+V+I+G D++++++ +LR+ IG+V QEP LF TIYENI GNE A+ +VVE+
Sbjct: 1042 YDPTAGKVMIEGKDIKKLDLKALRKHIGLVQQEPALFATTIYENILYGNEGASQSEVVES 1101
Query: 1510 CKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDT 1689
+ANA+ FI LP+GY T+VGE+GVQ+SGGQ+QRIAIARA++KNP ILLLDEATSALD
Sbjct: 1102 AMLANAHSFITSLPEGYSTKVGERGVQMSGGQRQRIAIARAILKNPAILLLDEATSALDV 1161
Query: 1690 EAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEEL-MSKQGIF 1866
E+ER VQ ALD+ A RTT++VAHRLSTI+N D I V G IVE GSH +L ++K G +
Sbjct: 1162 ESERVVQQALDRLMANRTTVVVAHRLSTIKNADTISVLHGGKIVEQGSHRKLVLNKSGPY 1221
Query: 1867 YDM 1875
+ +
Sbjct: 1222 FKL 1224
Score = 318 bits (816), Expect = 5e-85
Identities = 203/579 (35%), Positives = 303/579 (52%), Gaps = 7/579 (1%)
Frame = +1
Query: 2023 EEVEECKAPPTSMFKIFKFNG--DKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLP 2196
E+ +E P S+ K+F F D V SV P+F + + ++ N+ L
Sbjct: 10 EKEKEMTQPKVSLLKLFSFADFYDCVLMTLGSVGACIHGASV-PIFFIFFGKLINIIGLA 68
Query: 2197 ---ADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDI 2367
Q V + FV + + + C GE K+R +++L QDI
Sbjct: 69 YLFPKQASHRVAKYSLDFVYLSVAILFSSWLEVACWMHTGERQAAKMRRAYLRSMLSQDI 128
Query: 2368 AFYDDLRHGTGKLCTRFATDAPNVRYVFT-RLPVVLASIVTICGALGIGFYYGWQXXXXX 2544
+ +D TG++ + +D V+ + ++ L I IGF WQ
Sbjct: 129 SLFDT-EASTGEVISAITSDILVVQDALSEKVGNFLHYISRFIAGFAIGFTSVWQISLVT 187
Query: 2545 XXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYC 2724
+ G + G R + +AG++A + + ++RTV + +E+ Y
Sbjct: 188 LSIVPLIALAGGIYAFVAIGLIARVRKSYIKAGEIAEEVIGNVRTVQAFTGEERAVRLYR 247
Query: 2725 EYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAI 2904
E L + K T G ++F +A + S+ V++ + +
Sbjct: 248 EALENTYKYGRKAGLTKGLGLGSMHCVLFLSWALLVWFTSVVVHKDIADGGKSFTTMLNV 307
Query: 2905 SFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGI-VKPITGNISIRNVF 3081
G +G I V+A+ AA +F +IE T + + SG + + G+I ++
Sbjct: 308 VIAGLSLGQAAPDISAFVRAKAAAYPIFKMIERNTVTKTSAKSGRKLGKVDGHIQFKDAT 367
Query: 3082 FNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNI 3261
F+YP+R D + L I AGK VALVG SG GKST++ L+ERFY G +++DG+NI
Sbjct: 368 FSYPSRPDVVIFDRLNLAIPAGKIVALVGGSGSGKSTVISLIERFYEPISGAVLLDGNNI 427
Query: 3262 RNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLP 3441
L+I LR Q+ +V+QEP LF TI ENI YG + + T +EI AAK++ +FI LP
Sbjct: 428 SELDIKWLRGQIGLVNQEPALFATTIRENILYGKD-DATAEEITRAAKLSEAISFINNLP 486
Query: 3442 DGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAK 3621
+G++T VGE+G QLSGGQKQRIAI+RA+V++PS+LLLDEATSALD ESEK VQEALD
Sbjct: 487 EGFETQVGERGIQLSGGQKQRIAISRAIVKNPSILLLDEATSALDAESEKSVQEALDRVM 546
Query: 3622 QGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELI 3738
GRT +V+AHRLST++N+D+IA+V EGKIVE G H+ LI
Sbjct: 547 VGRTTVVVAHRLSTVRNADIIAVVHEGKIVEFGNHENLI 585
>gi|15236067|ref|NP_194326.1| multidrug resistance P-glycoprotein,
putative [Arabidopsis thaliana]
gi|7442648|pir||T04251 P-glycoprotein 2 - Arabidopsis thaliana
gi|2108252|emb|CAA71277.1| P-glycoprotein-2 [Arabidopsis thaliana]
gi|2108254|emb|CAA71276.1| P-glycoprotein-2 [Arabidopsis thaliana]
gi|4538925|emb|CAB39661.1| P-glycoprotein-2 (pgp2) [Arabidopsis
thaliana]
gi|7269447|emb|CAB79451.1| P-glycoprotein-2 (pgp2) [Arabidopsis
thaliana]
Length = 1233
Score = 723 bits (1867), Expect = 0.0
Identities = 430/1243 (34%), Positives = 682/1243 (54%), Gaps = 14/1243 (1%)
Frame = +1
Query: 94 KLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVD 273
K++ +F + D +L+ G+V A IHGA P+ I G +
Sbjct: 19 KVSLLKLFSFADFYDCVLMTLGSVGACIHGASVPIFFIFFGKL----------------- 61
Query: 274 NVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYL 453
+N GL + + + V KY + ++ L V + F+S++++AC+ ER K+R+ YL
Sbjct: 62 -INIIGLAYLFPKQASHRVAKYSLDFVYLSVAILFSSWLEVACWMHTGERQAAKMRRAYL 120
Query: 454 KAILRQQIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYS 630
+++L Q I FD + TG + + +T D+ V++ L +K + + F+AG+ +GF
Sbjct: 121 RSMLSQDISLFDTEASTGEVISAITSDILVVQDALSEKVGNFLHYISRFIAGFAIGFTSV 180
Query: 631 WSMTLVMMGFAPLIVLSG---AKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLN 801
W ++LV + PLI L+G A ++ + R R ++Y AG IAEE ++RTV +
Sbjct: 181 WQISLVTLSIVPLIALAGGIYAFVAIGLIARVR---KSYIKAGEIAEEVIGNVRTVQAFT 237
Query: 802 GHKRELDRFYNALE----VGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIIND 969
G +R + + ALE GR+ G+ K G+G+G + ++ S+AL W+ S ++ D
Sbjct: 238 GEERAVRLYREALENTYKYGRKAGLTK----GLGLGSMHCVLFLSWALLVWFTSVVVHKD 293
Query: 970 PTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGI 1149
D G FT V+ SLG A P +++F A+ AA + ++I + + G
Sbjct: 294 IA-DGGKSFTTMLNVVIAGLSLGQAAPDISAFVRAKAAAYPIFKMIERNTVTKTSAKSGR 352
Query: 1150 LVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRF 1329
+ + G I FKD F YPSR D+ + ++L + AG +ALVG SG GKST+++L++RF
Sbjct: 353 KLGKVDGHIQFKDATFSYPSRPDVVIFDRLNLAIPAGKIVALVGGSGSGKSTVISLIERF 412
Query: 1330 YDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEA 1509
Y+P G VL+DG ++ E+++ LR QIG+V+QEP LF TI ENI G + AT +++ A
Sbjct: 413 YEPISGAVLLDGNNISELDIKWLRGQIGLVNQEPALFATTIRENILYGKDDATAEEITRA 472
Query: 1510 CKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDT 1689
K++ A FI LP+G+ T+VGE+G+QLSGGQKQRIAI+RA+VKNP ILLLDEATSALD
Sbjct: 473 AKLSEAISFINNLPEGFETQVGERGIQLSGGQKQRIAISRAIVKNPSILLLDEATSALDA 532
Query: 1690 EAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFY 1869
E+E+ VQ ALD+ GRTT++VAHRLST+RN D I V G IVE G+HE L+S Y
Sbjct: 533 ESEKSVQEALDRVMVGRTTVVVAHRLSTVRNADIIAVVHEGKIVEFGNHENLISNPDGAY 592
Query: 1870 DMTXXXXXXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLA--EEVEECK 2043
+ + + T+S HS + + + K
Sbjct: 593 S-SLLRLQETASLQRNPSLNRTLSR-PHSIKYSRELSRTRSSFCSERESVTRPDGADPSK 650
Query: 2044 APPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANVY 2223
++ +++ + S P+FAL ++ Y D+ Q +
Sbjct: 651 KVKVTVGRLYSMIRPDWMYGVCGTICAFIAGSQMPLFALGVSQALVSYYSGWDETQKEIK 710
Query: 2224 FWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGK 2403
+F + + + C G GE LT+++R F+ +L+ +I ++D++ + +
Sbjct: 711 KIAILFCCASVITLIVYTIEHICFGTMGERLTLRVRENMFRAILKNEIGWFDEVDNTSSM 770
Query: 2404 LCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGY 2580
L +R +DA ++ V R ++L ++ + + I F W+ G
Sbjct: 771 LASRLESDATLLKTIVVDRSTILLQNLGLVVTSFIIAFILNWRLTLVVLATYPLVISGHI 830
Query: 2581 FE--MQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTN 2754
E +G + L +A +A ++V +IRTV + +E+ Y L EP ++
Sbjct: 831 SEKLFMQGYGGDLNKAYL--KANMLAGESVSNIRTVAAFCAEEKILELYSRELLEPSKSS 888
Query: 2755 LKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNT 2934
+ G + SQ IF Y A + GS +++ V + F + +G T
Sbjct: 889 FRRGQIAGLFYGVSQFFIFSSYGLALWYGSTLMDKGLAGFKSVMKTFMVLIVTALAMGET 948
Query: 2935 TSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKV 3114
+ PD++K + +F +++ T I S + + G I ++ V F+YP+R D +
Sbjct: 949 LALAPDLLKGNQMVASVFEILDRKTQIVG-ETSEELNNVEGTIELKGVHFSYPSRPDVVI 1007
Query: 3115 LQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQ 3294
+ F L ++AGK++ALVG SG GKS+++ L+ RFY+ G +MI+G +I+ L++ +LR+
Sbjct: 1008 FRDFDLIVRAGKSMALVGQSGSGKSSVISLILRFYDPTAGKVMIEGKDIKKLDLKALRKH 1067
Query: 3295 VCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKG 3474
+ +V QEP LF TI ENI YG N + E+VE+A +AN H+FI LP+GY T VGE+G
Sbjct: 1068 IGLVQQEPALFATTIYENILYG-NEGASQSEVVESAMLANAHSFITSLPEGYSTKVGERG 1126
Query: 3475 TQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHR 3654
Q+SGGQ+QRIAIARA++++P++LLLDEATSALD ESE++VQ+ALD RT +V+AHR
Sbjct: 1127 VQMSGGQRQRIAIARAILKNPAILLLDEATSALDVESERVVQQALDRLMANRTTVVVAHR 1186
Query: 3655 LSTIQNSDVIAIVSEGKIVEKGTHDELI-RKSEIYQKFCETQR 3780
LSTI+N+D I+++ GKIVE+G+H +L+ KS Y K Q+
Sbjct: 1187 LSTIKNADTISVLHGGKIVEQGSHRKLVLNKSGPYFKLISLQQ 1229
Score = 372 bits (956), Expect = e-101
Identities = 220/603 (36%), Positives = 340/603 (55%), Gaps = 8/603 (1%)
Frame = +1
Query: 91 VKLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGV 270
VK+T G Y D + + GT+ A I G+ PL A+ G++ + +
Sbjct: 652 VKVT-VGRLYSMIRPDWMYGVCGTICAFIAGSQMPLFAL---GVSQALVSYYSG------ 701
Query: 271 DNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNY 450
DE E+ K I + V+ ++ CF + ERL ++R+N
Sbjct: 702 ------------WDETQKEIKKIAILFCCASVITLIVYTIEHICFGTMGERLTLRVRENM 749
Query: 451 LKAILRQQIQWFDK--QQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFF 624
+AIL+ +I WFD+ + L +RL D ++ + D+ +L+Q + + + F
Sbjct: 750 FRAILKNEIGWFDEVDNTSSMLASRLESDATLLKTIVVDRSTILLQNLGLVVTSFIIAFI 809
Query: 625 YSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNG 804
+W +TLV++ PL++ M + Y A +A E+ S+IRTV +
Sbjct: 810 LNWRLTLVVLATYPLVISGHISEKLFMQGYGGDLNKAYLKANMLAGESVSNIRTVAAFCA 869
Query: 805 HKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDR 984
++ L+ + L ++ + G+ G S ++SSY LA WYGSTL+ D+
Sbjct: 870 EEKILELYSRELLEPSKSSFRRGQIAGLFYGVSQFFIFSSYGLALWYGSTLM------DK 923
Query: 985 GL-----IFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGI 1149
GL + F ++ + ++G L ++V +++ +I + E +
Sbjct: 924 GLAGFKSVMKTFMVLIVTALAMGETLALAPDLLKGNQMVASVFEILDRKTQIVGETSEEL 983
Query: 1150 LVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRF 1329
+N++G I K VHF YPSR D+ + + L ++AG +ALVG SG GKS++++L+ RF
Sbjct: 984 --NNVEGTIELKGVHFSYPSRPDVVIFRDFDLIVRAGKSMALVGQSGSGKSSVISLILRF 1041
Query: 1330 YDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEA 1509
YDPT G+V+I+G D++++++ +LR+ IG+V QEP LF TIYENI GNE A+ +VVE+
Sbjct: 1042 YDPTAGKVMIEGKDIKKLDLKALRKHIGLVQQEPALFATTIYENILYGNEGASQSEVVES 1101
Query: 1510 CKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDT 1689
+ANA+ FI LP+GY T+VGE+GVQ+SGGQ+QRIAIARA++KNP ILLLDEATSALD
Sbjct: 1102 AMLANAHSFITSLPEGYSTKVGERGVQMSGGQRQRIAIARAILKNPAILLLDEATSALDV 1161
Query: 1690 EAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEEL-MSKQGIF 1866
E+ER VQ ALD+ A RTT++VAHRLSTI+N D I V G IVE GSH +L ++K G +
Sbjct: 1162 ESERVVQQALDRLMANRTTVVVAHRLSTIKNADTISVLHGGKIVEQGSHRKLVLNKSGPY 1221
Query: 1867 YDM 1875
+ +
Sbjct: 1222 FKL 1224
Score = 318 bits (816), Expect = 5e-85
Identities = 203/579 (35%), Positives = 303/579 (52%), Gaps = 7/579 (1%)
Frame = +1
Query: 2023 EEVEECKAPPTSMFKIFKFNG--DKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLP 2196
E+ +E P S+ K+F F D V SV P+F + + ++ N+ L
Sbjct: 10 EKEKEMTQPKVSLLKLFSFADFYDCVLMTLGSVGACIHGASV-PIFFIFFGKLINIIGLA 68
Query: 2197 ---ADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDI 2367
Q V + FV + + + C GE K+R +++L QDI
Sbjct: 69 YLFPKQASHRVAKYSLDFVYLSVAILFSSWLEVACWMHTGERQAAKMRRAYLRSMLSQDI 128
Query: 2368 AFYDDLRHGTGKLCTRFATDAPNVRYVFT-RLPVVLASIVTICGALGIGFYYGWQXXXXX 2544
+ +D TG++ + +D V+ + ++ L I IGF WQ
Sbjct: 129 SLFDT-EASTGEVISAITSDILVVQDALSEKVGNFLHYISRFIAGFAIGFTSVWQISLVT 187
Query: 2545 XXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYC 2724
+ G + G R + +AG++A + + ++RTV + +E+ Y
Sbjct: 188 LSIVPLIALAGGIYAFVAIGLIARVRKSYIKAGEIAEEVIGNVRTVQAFTGEERAVRLYR 247
Query: 2725 EYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAI 2904
E L + K T G ++F +A + S+ V++ + +
Sbjct: 248 EALENTYKYGRKAGLTKGLGLGSMHCVLFLSWALLVWFTSVVVHKDIADGGKSFTTMLNV 307
Query: 2905 SFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGI-VKPITGNISIRNVF 3081
G +G I V+A+ AA +F +IE T + + SG + + G+I ++
Sbjct: 308 VIAGLSLGQAAPDISAFVRAKAAAYPIFKMIERNTVTKTSAKSGRKLGKVDGHIQFKDAT 367
Query: 3082 FNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNI 3261
F+YP+R D + L I AGK VALVG SG GKST++ L+ERFY G +++DG+NI
Sbjct: 368 FSYPSRPDVVIFDRLNLAIPAGKIVALVGGSGSGKSTVISLIERFYEPISGAVLLDGNNI 427
Query: 3262 RNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLP 3441
L+I LR Q+ +V+QEP LF TI ENI YG + + T +EI AAK++ +FI LP
Sbjct: 428 SELDIKWLRGQIGLVNQEPALFATTIRENILYGKD-DATAEEITRAAKLSEAISFINNLP 486
Query: 3442 DGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAK 3621
+G++T VGE+G QLSGGQKQRIAI+RA+V++PS+LLLDEATSALD ESEK VQEALD
Sbjct: 487 EGFETQVGERGIQLSGGQKQRIAISRAIVKNPSILLLDEATSALDAESEKSVQEALDRVM 546
Query: 3622 QGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELI 3738
GRT +V+AHRLST++N+D+IA+V EGKIVE G H+ LI
Sbjct: 547 VGRTTVVVAHRLSTVRNADIIAVVHEGKIVEFGNHENLI 585
>gi|22331385|ref|NP_683599.1| P-glycoprotein, putative [Arabidopsis
thaliana]
Length = 1221
Score = 721 bits (1860), Expect = 0.0
Identities = 451/1242 (36%), Positives = 682/1242 (54%), Gaps = 19/1242 (1%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
IF + VDL+L+ G + AV G P++ + G + +N G
Sbjct: 10 IFMHANSVDLVLMGLGLIGAVGDGFITPIIFFITGLL------------------LNDIG 51
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
F ++K + L++ + CF ER ++R+ YL+A+LRQ
Sbjct: 52 DSSFGDKTFMHAIMKNAV------ALLYVAGASLVICF--VGERQASRMREKYLRAVLRQ 103
Query: 472 QIQWFDKQ--QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTL 645
+ +FD T ++ ++ D +++ L +K + +AF+A Y VGF W +T+
Sbjct: 104 DVGYFDLHVTSTSDVITSVSSDTLVIQDVLSEKLPNFLMSASAFVASYIVGFIMLWRLTI 163
Query: 646 VMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDR 825
V F L+++ G +++ +R +E Y AG+IAE+ S +RTV++ ++ + +
Sbjct: 164 VGFPFFILLLIPGLMCGRALINISRKIREEYNEAGSIAEQAISLVRTVYAFGSERKMISK 223
Query: 826 FYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVF 1005
F ALE + G+ + GI +G SN Y+ + WYGS +++ G IF V
Sbjct: 224 FSAALEGSVKLGLRQGIAKGIAIG-SNGVTYAIWGFMTWYGSRMVMYHGA-KGGTIFAVI 281
Query: 1006 FAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFK 1185
+ G TSLG L +L F A A ++ VI P ID + G +++N+KG++ FK
Sbjct: 282 ICITYGGTSLGRGLSNLKYFSEAVVAGERIIEVIKRVPDIDSDNPRGQVLENIKGEVQFK 341
Query: 1186 DVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDG 1365
V F Y SR + + + L + +G +ALVG SG GKST+++LLQRFYDP G +LIDG
Sbjct: 342 HVKFMYSSRPETPIFDDLCLRIPSGKSVALVGGSGSGKSTVISLLQRFYDPIVGEILIDG 401
Query: 1366 VDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKR 1545
V ++++ V LR Q+G+VSQEP LF +I ENI G E A+ D+VVEA K +NA+DFI +
Sbjct: 402 VSIKKLQVKWLRSQMGLVSQEPALFATSIEENILFGKEDASFDEVVEAAKSSNAHDFISQ 461
Query: 1546 LPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQ 1725
P GY T+VGE+GVQ+SGGQKQRI+IARA++K+P +LLLDEATSALD+E+ER VQ ALD
Sbjct: 462 FPLGYKTQVGERGVQMSGGQKQRISIARAIIKSPTLLLLDEATSALDSESERVVQEALDN 521
Query: 1726 AQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXX 1905
A GRTTI++AHRLSTIRNVD I VFK G IVE+GSHEELM Y +
Sbjct: 522 ATIGRTTIVIAHRLSTIRNVDVICVFKNGQIVETGSHEELMENVDGQY-TSLVRLQIMEN 580
Query: 1906 XEAGKDIEDTISESAHSHL---------XXXXXXXXXXXXXXXIHQLAEEVEECKAPPTS 2058
E+ ++ ++ E S+ LA + + K P S
Sbjct: 581 EESNDNVSVSMREGQFSNFNKDVKYSSRLSIQSRSSLFATSSIDTNLAGSIPKDKKP--S 638
Query: 2059 MFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPA-DQMQANVYFWCG 2235
++ N + ++ P++A + +VY L + D+M+ +
Sbjct: 639 FKRLMAMNKPEWKHALYGCLSAVLYGALHPIYAYASGSMVSVYFLTSHDEMKEKTRIYVL 698
Query: 2236 MFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTR 2415
+FV + + F+ GE LT ++R LL +++++D+ + +G +C+R
Sbjct: 699 LFVGLAVLCFLISIIQQYSFAYMGEYLTKRIRENILSKLLTFEVSWFDEDENSSGSICSR 758
Query: 2416 FATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQ 2592
A DA VR V R+ +++ +I + A +G W+ + G F Q
Sbjct: 759 LAKDANVVRSLVGERVSLLVQTISAVSVACTLGLAISWK--LSIVMIAIQPVVVGCFYTQ 816
Query: 2593 MRFGKQI--RDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHA 2766
K I + + +E+ K+A++AV +IRT+ + + QE+ P N++ +
Sbjct: 817 RIVLKSISKKAIKAQDESSKLAAEAVSNIRTITAFSSQERILKLLKMVQEGPQRENIRQS 876
Query: 2767 HTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFI 2946
G V A S+SL+ A ++ G+ + + + +F G++I + +
Sbjct: 877 WLAGIVLATSRSLMTCTSALNYWYGARLIIDGKITSKAFFELFILFVSTGRVIADAGAMT 936
Query: 2947 PDVVKARLAASLLFYLIEHPTPIDSLSDSGIV-KPITGNISIRNVFFNYPTRKDTKVLQG 3123
D+ K A +F +++ T I+ G V + I G I NV F YPTR D + +
Sbjct: 937 MDLAKGSDAVGSVFAVLDRYTNIEPEKPDGFVPQNIKGQIKFVNVDFAYPTRPDVIIFKN 996
Query: 3124 FTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCI 3303
F++DI GK+ A+VG SG GKSTI+GL+ERFY+ KG++ IDG +IR+ ++ SLR+ + +
Sbjct: 997 FSIDIDEGKSTAIVGPSGSGKSTIIGLIERFYDPLKGIVKIDGRDIRSYHLRSLRQHIGL 1056
Query: 3304 VSQEPTLFDCTIGENICY-GTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQ 3480
VSQEP LF TI ENI Y G + + EI+EAAK AN H+FI+ L DGYDT+ G++G Q
Sbjct: 1057 VSQEPILFAGTIRENIMYGGASDKIDESEIIEAAKAANAHDFIVTLSDGYDTYCGDRGVQ 1116
Query: 3481 LSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLS 3660
LSGGQKQRIAIARA++++PSVLLLDEATSALD +SE++VQ+AL GRT +VIAHRLS
Sbjct: 1117 LSGGQKQRIAIARAVLKNPSVLLLDEATSALDNQSERMVQDALGRLMVGRTSVVIAHRLS 1176
Query: 3661 TIQNSDVIAIVSEGKIVEKGTHDELIRK--SEIYQKFCETQR 3780
TIQN D I ++ +GK+VE GTH L+ K + +Y QR
Sbjct: 1177 TIQNCDTITVLDKGKVVECGTHSSLLAKGPTGVYFSLVSLQR 1218
>gi|9294571|dbj|BAB02852.1| multidrug resistance p-glycoprotein; ABC
transporter-like protein [Arabidopsis thaliana]
Length = 1228
Score = 718 bits (1853), Expect = 0.0
Identities = 435/1223 (35%), Positives = 678/1223 (54%), Gaps = 12/1223 (0%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
IF + GVD +L+ G + AV G P+L F + +N G
Sbjct: 10 IFMHADGVDWMLMGLGLIGAVGDGFITPIL------------------FFITAMLLNDFG 51
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
+ + F + K + L + + +++ C+ ER K+R+ YL+A+LRQ
Sbjct: 52 SFSFNDETFMQPISKNALAMLYVACASWVICFLEGYCWTRTGERQAAKMRERYLRAVLRQ 111
Query: 472 QIQWFDKQ--QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTL 645
+ +FD T ++ ++ D +++ L +K ++ +AF+ Y VGF W +T+
Sbjct: 112 DVGYFDLHVTSTSDIITSVSSDSLVIQDFLSEKLPNILMNASAFVGSYIVGFMLLWRLTI 171
Query: 646 VMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDR 825
V F L+++ G +++ +R +E Y AG+IAE+ SS+RTV++ K+ +++
Sbjct: 172 VGFPFIILLLIPGLMYGRALIGISRKIREEYNEAGSIAEQAISSVRTVYAFVSEKKMIEK 231
Query: 826 FYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVF 1005
F +AL+ + G+ + GI +G SN +Y+ + WYGS +++N + G + TV
Sbjct: 232 FSDALQGSVKLGLRQGLAKGIAIG-SNGIVYAIWGFLTWYGSRMVMNYG-YKGGTVSTVT 289
Query: 1006 FAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFK 1185
V G T+LG AL +L F A A + ++I P ID +L G +++ ++G++ F
Sbjct: 290 VCVTFGGTALGQALSNLKYFSEAFVAGERIQKMIKRVPDIDSDNLNGHILETIRGEVEFN 349
Query: 1186 DVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDG 1365
+V +YPSR + + + L++ +G +ALVG SG GKST+++LLQRFYDP +G +LID
Sbjct: 350 NVKCKYPSRPETLIFDDLCLKIPSGKTVALVGGSGSGKSTVISLLQRFYDPNEGDILIDS 409
Query: 1366 VDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKR 1545
V + + V LR Q+G+VSQEP LF +I ENI G E A+ D+VVEA K +NA++FI +
Sbjct: 410 VSINNMQVKWLRSQMGMVSQEPSLFATSIKENILFGKEDASFDEVVEAAKASNAHNFISQ 469
Query: 1546 LPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQ 1725
P GY T+VGE+GV +SGGQKQRIAIARAL+K+P ILLLDEATSALD E+ER VQ ALD
Sbjct: 470 FPHGYQTQVGERGVHMSGGQKQRIAIARALIKSPIILLLDEATSALDLESERVVQEALDN 529
Query: 1726 AQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXX 1905
A GRTTI++AHRLSTIRN D I V G IVE+GSH++LM G + +
Sbjct: 530 ASVGRTTIVIAHRLSTIRNADIICVLHNGCIVETGSHDKLMEIDGKYTSLVRLQQMKNEE 589
Query: 1906 X--EAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKAPPTSMFK-IFK 2076
+++ S + L + L++ + + K P FK +
Sbjct: 590 SCDNTSVGVKEGRVSSLRNDLDYNPRDLAHSMSSSIVTNLSDSIPQDKKPLVPSFKRLMA 649
Query: 2077 FNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLP-ADQMQANVYFWCGMFVLMG 2253
N + +V P++A + +V+ L +Q++ N + +F G
Sbjct: 650 MNRPEWKHALCGCLSASLGGAVQPIYAYSSGLMISVFFLTNHEQIKENTRIYVLLF--FG 707
Query: 2254 ITFFVGFFTSAN---CLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFAT 2424
+ F FFTS + GE LT ++R + +L ++ ++D+ + +G +C+R A
Sbjct: 708 LALFT-FFTSISQQYSFSYMGEYLTKRIREQMLSKILTFEVNWFDEEENSSGAICSRLAK 766
Query: 2425 DAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRF 2601
DA VR V R+ +++ +I T+ A IG W+ + Y + +
Sbjct: 767 DANVVRSLVGERMSLLVQTISTVMVACTIGLVIAWRFTIVMISVQPVIIVCYYIQRVLLK 826
Query: 2602 GKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGA 2781
+ +E+ K+A++AV +IRT+ + + QE+ P + + + G
Sbjct: 827 NMSKKAIIAQDESSKLAAEAVSNIRTITTFSSQERIMKLLERVQEGPRRESARQSWLAGI 886
Query: 2782 VFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVK 2961
+ +QSLI A F+ G + M + +F G+ I + D+ K
Sbjct: 887 MLGTTQSLITCTSALNFWYGGKLIADGKMVSKAFFELFLIFKTTGRAIAEAGTMTTDLAK 946
Query: 2962 ARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDI 3138
+ +F +++ T I+ + G I++ I G I+ NV F YPTR + + F+++I
Sbjct: 947 GSNSVDSVFTVLDRRTTIEPENPDGYILEKIKGQITFLNVDFAYPTRPNMVIFNNFSIEI 1006
Query: 3139 KAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEP 3318
GK+ A+VG S GKST++GL+ERFY+ +G++ IDG +IR+ ++ SLR+ + +VSQEP
Sbjct: 1007 HEGKSTAIVGPSRSGKSTVIGLIERFYDPLQGIVKIDGRDIRSYHLRSLRQHMSLVSQEP 1066
Query: 3319 TLFDCTIGENICYGTNRN-VTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQ 3495
TLF TI ENI YG N + EI+EA K AN H FI L DGYDT+ G++G QLSGGQ
Sbjct: 1067 TLFAGTIRENIMYGRASNKIDESEIIEAGKTANAHEFITSLSDGYDTYCGDRGVQLSGGQ 1126
Query: 3496 KQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNS 3675
KQRIAIAR ++++PS+LLLDEATSALD++SE++VQ+AL+ G+T +VIAHRLSTIQN
Sbjct: 1127 KQRIAIARTILKNPSILLLDEATSALDSQSERVVQDALEHVMVGKTSVVIAHRLSTIQNC 1186
Query: 3676 DVIAIVSEGKIVEKGTHDELIRK 3744
D IA++ +GK+VE GTH L+ K
Sbjct: 1187 DTIAVLDKGKVVESGTHASLLAK 1209
Score = 314 bits (804), Expect = 1e-83
Identities = 191/526 (36%), Positives = 293/526 (55%), Gaps = 2/526 (0%)
Frame = +1
Query: 2212 ANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRH 2391
A +Y C +V I F G+ C R GE K+R + +LRQD+ ++D
Sbjct: 70 AMLYVACASWV---ICFLEGY-----CWTRTGERQAAKMRERYLRAVLRQDVGYFDLHVT 121
Query: 2392 GTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXX 2568
T + T ++D+ ++ ++ +LP +L + G+ +GF W+
Sbjct: 122 STSDIITSVSSDSLVIQDFLSEKLPNILMNASAFVGSYIVGFMLLWRLTIVGFPFIILLL 181
Query: 2569 MGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFN 2748
+ G + G + + EAG +A QA+ +RTV++ +++ + + L+
Sbjct: 182 IPGLMYGRALIGISRKIREEYNEAGSIAEQAISSVRTVYAFVSEKKMIEKFSDALQGSVK 241
Query: 2749 TNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIG 2928
L+ G S +++ ++ + GS V + V V ++F G +G
Sbjct: 242 LGLRQGLAKGIAIG-SNGIVYAIWGFLTWYGSRMVMNYGYKGGTVSTVTVCVTFGGTALG 300
Query: 2929 NTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKD 3105
S + +A +A + +I+ IDS + +G I++ I G + NV YP+R +
Sbjct: 301 QALSNLKYFSEAFVAGERIQKMIKRVPDIDSDNLNGHILETIRGEVEFNNVKCKYPSRPE 360
Query: 3106 TKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSL 3285
T + L I +GKTVALVG SG GKST++ LL+RFY+ ++G I+ID +I N+ + L
Sbjct: 361 TLIFDDLCLKIPSGKTVALVGGSGSGKSTVISLLQRFYDPNEGDILIDSVSINNMQVKWL 420
Query: 3286 REQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVG 3465
R Q+ +VSQEP+LF +I ENI +G + ++ E+VEAAK +N HNFI P GY T VG
Sbjct: 421 RSQMGMVSQEPSLFATSIKENILFG-KEDASFDEVVEAAKASNAHNFISQFPHGYQTQVG 479
Query: 3466 EKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVI 3645
E+G +SGGQKQRIAIARAL++SP +LLLDEATSALD ESE++VQEALD A GRT +VI
Sbjct: 480 ERGVHMSGGQKQRIAIARALIKSPIILLLDEATSALDLESERVVQEALDNASVGRTTIVI 539
Query: 3646 AHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRI 3783
AHRLSTI+N+D+I ++ G IVE G+HD+L+ Y Q++
Sbjct: 540 AHRLSTIRNADIICVLHNGCIVETGSHDKLMEIDGKYTSLVRLQQM 585
>gi|45735908|dbj|BAD12940.1| putative P-glycoprotein 1 [Oryza sativa
(japonica cultivar-group)]
Length = 1344
Score = 717 bits (1851), Expect = 0.0
Identities = 434/1257 (34%), Positives = 677/1257 (53%), Gaps = 30/1257 (2%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F + G+D +L+ GT+ A++HG P VFLR F VD+
Sbjct: 98 LFSFADGLDYVLMTLGTLGALVHGCSLP-----------VFLRF----FADLVDSFGSHA 142
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
P D VVKY Y+LV+G ++ +S+ +I+C+ ER ++R YL A L Q
Sbjct: 143 AHP---DTMLRLVVKYAFYFLVVGAAIWASSWAEISCWMWTGERQSTRMRIRYLHAALHQ 199
Query: 472 QIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLV 648
+ +FD +T ++ + D V++ + +K L+ A F++G+ VGF +W + LV
Sbjct: 200 DVSFFDTDVRTSDVIHAINADAVVVQDAISEKLGNLIHYLATFVSGFVVGFTAAWQLALV 259
Query: 649 MMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRF 828
+ PLI + G + ++A + Q+ + A IAE+ + IR V S G +R + +
Sbjct: 260 TLAVVPLIAVIGGLSAAALAKLSSRSQDALSDASGIAEQALAQIRIVQSFVGEERVMRAY 319
Query: 829 YNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFF 1008
AL V ++ G GIG+G + ++ YAL WYG L+ T + GL F
Sbjct: 320 SAALAVAQRIGYRSGFAKGIGLGGTYFTVFCCYALLLWYGGHLVRRAHT-NGGLAIATMF 378
Query: 1009 AVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKD 1188
+V+ G +LG + P +A+F AR AA+ + R++ P ++ G+ ++ + G + +D
Sbjct: 379 SVMIGGLALGQSAPSMAAFAKARVAAAKIFRMMEHKPSMEREG--GVELEAVTGRVELRD 436
Query: 1189 VHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGV 1368
V F YPSR D+ +L+G+SL + AG IALVGSSG GKST+V+L++RFY+P G +L+DG
Sbjct: 437 VEFSYPSRPDVGILRGLSLSVPAGKTIALVGSSGSGKSTVVSLIERFYEPNAGTILLDGH 496
Query: 1369 DLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRL 1548
DLR++N+ LR QIG+VSQEP LF TI EN+ +G + AT +++ EA ++ANA+ FI +L
Sbjct: 497 DLRDLNLRWLRRQIGLVSQEPALFATTIRENLLLGRDGATQEELEEAARVANAHSFIVKL 556
Query: 1549 PDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQA 1728
PD Y T+VGE+G+QLSGGQKQRIAIARA+++NP ILLLDEATSALD+E+E+ VQ ALD+
Sbjct: 557 PDAYNTQVGERGLQLSGGQKQRIAIARAMLRNPAILLLDEATSALDSESEKLVQEALDRF 616
Query: 1729 QAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFY------------- 1869
GRTT+++AHRLSTIR D + V + G I E G+H+ELM++ Y
Sbjct: 617 MIGRTTLVIAHRLSTIRKADLVAVLQGGAISEVGTHDELMARGDGTYARLIRMQEQAHEA 676
Query: 1870 DMTXXXXXXXXXXEAGKDIEDTI-------SESAHSHLXXXXXXXXXXXXXXXIHQLAEE 2028
+ A + I S +S Q ++
Sbjct: 677 ALVAARRSSARPSSARNSVSSPIITRNSSYGRSPYSRRLSDADFITGLGLGVDSKQ-QQQ 735
Query: 2029 VEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLP-ADQ 2205
+ +S +++ K N + G+ S + +FA V + + +VY P A
Sbjct: 736 QHYFRVQASSFWRLAKMNSPEWGYALVASLGSMVCGSFSAIFAYVLSAVLSVYYAPDAAY 795
Query: 2206 MQANVYFWCGMFVLMGITFFVGFFTSANCL--GRCGESLTMKLRFEAFKNLLRQDIAFYD 2379
M + +C ++L+G++ F + L GE+LT ++R +LR +IA++D
Sbjct: 796 MDRQIAKYC--YLLIGMSSAALLFNTVQHLFWDTVGENLTKRVRERMLAAVLRNEIAWFD 853
Query: 2380 DLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXX 2556
+ + ++ R A DA NVR + R+ +++ + + A GF W+
Sbjct: 854 MEDNSSARIAARLALDAQNVRSAIGDRISIIVQNSALMLVACTAGFVLQWRLALVLLAVF 913
Query: 2557 XXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLR 2736
+ G + A ++A +AV ++RTV + + + + L
Sbjct: 914 PLVVAATVLQKMFLKGFSGDLERAHARATQIAGEAVANVRTVAAFGSEAKIVGLFEANLA 973
Query: 2737 EPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCG 2916
P G+ + +Q L++ YA + + V RVF +
Sbjct: 974 GPLRRCFWKGQIAGSGYGVAQFLLYASYALGLWYAAWLVKHGVSDFSKTIRVFMVLMVSA 1033
Query: 2917 QMIGNTTSFIPDVVKARLAASLLFYLIEHPTPI--DSLSDSGIVKPITGNISIRNVFFNY 3090
T + PD VK A +F ++ T I D + + + + G + +++V F Y
Sbjct: 1034 NGAAETLTLAPDFVKGGRAMQAVFEAMDRRTEIEPDDVDAAAVPERPRGEVELKHVDFAY 1093
Query: 3091 PTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNL 3270
P+R + +V + +L +AG+T+ALVG SGCGKS+++ L++RFY + G +++DG ++R
Sbjct: 1094 PSRPEVQVFRDLSLRARAGRTLALVGASGCGKSSVLALVQRFYEPNSGRVLLDGRDLRKF 1153
Query: 3271 NISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGY 3450
N+ SLR + +V QEP LF TI +NI YG T E+VEAA AN H FI LP+GY
Sbjct: 1154 NLRSLRRAMALVPQEPFLFAATIHDNIAYG-REGATEAEVVEAATAANAHKFISALPEGY 1212
Query: 3451 DTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEAL-DAAKQG 3627
T VGE+G QLSGGQ+QRIAIARALV+ +LLLDEATSALD ESE+ VQEAL ++ G
Sbjct: 1213 GTLVGERGVQLSGGQRQRIAIARALVKQAPILLLDEATSALDAESERSVQEALASSSGSG 1272
Query: 3628 RTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELI--RKSEIYQKFCETQRIVES 3792
RT +V+AHRL+T++N+ IA++ +GK+ E+G+H L+ Y + + QR+ S
Sbjct: 1273 RTTIVVAHRLATVRNAHTIAVIDDGKVAEQGSHSHLLNHHPDGCYARMLQLQRLSHS 1329
>gi|17567271|ref|NP_510129.1| P-GlycoProtein related (pgp-15)
[Caenorhabditis elegans]
gi|7499666|pir||T21269 hypothetical protein F22E10.4 - Caenorhabditis
elegans
gi|3876294|emb|CAA91802.1| Hypothetical protein F22E10.4
[Caenorhabditis elegans]
Length = 1270
Score = 717 bits (1850), Expect = 0.0
Identities = 444/1267 (35%), Positives = 649/1267 (51%), Gaps = 37/1267 (2%)
Frame = +1
Query: 88 TVKLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVG 267
T ++ +G+F Y + D LL G + A+I G P+L I+ G +T L
Sbjct: 79 TQPVSIFGLFRYAKAFDHFLLFIGVICAIISGVSQPVLTIIAGRVTNAIL---------- 128
Query: 268 VDNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQN 447
+ +F ++ + +L +G+ + T+Y+Q CF+ R++ ++R
Sbjct: 129 --------VYAPQTKQFRNKATENVYIFLGIGIFVTITNYIQYMCFQHCCSRIMAQMRHR 180
Query: 448 YLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFY 627
Y+ ++LRQ WFDK +G + +L D +ER+REG+GDK +L++ A +A V + Y
Sbjct: 181 YVYSVLRQNAGWFDKHHSGTIATKLNDSMERIREGIGDKLGVLLRGVAMLVASVVVAYIY 240
Query: 628 SWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGH 807
W + +++G AP + + M++ M T E AG+IAEE+ +RTV + NG
Sbjct: 241 EWRLACMLLGVAPTCIGCMSLMARQMTATTVKELGGVEKAGSIAEESLMGVRTVQAFNGQ 300
Query: 808 KRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRG 987
+ ++R+ L GR+ I K + G+ G +++ F YG+ L+ G
Sbjct: 301 EEMVERYRVELNKGRKFAIWKGFWSGLFGGMFFFWLFAFQGCGFLYGAYLLSVGIIKSPG 360
Query: 988 LIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMK 1167
+F + A+L GS G PHL AR AA ++ I+ PKIDPYS +G +D +
Sbjct: 361 DVFIIVMAMLLGSYFTGLISPHLMVLLNARVAAGSIYETIDRVPKIDPYSKKGKFLDKVI 420
Query: 1168 GDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKG 1347
G + F++VHFRYP+RKD +L G++L ++ G +ALVG SGCGKST V LL R Y+P G
Sbjct: 421 GRVKFENVHFRYPTRKDAKILNGLNLTIEPGTSVALVGHSGCGKSTSVGLLTRLYEPEAG 480
Query: 1348 RVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANA 1527
V IDG D+RE+N+ LR IGIV QEP+LF+ TI+ N+ +GN +AT ++++E CKMANA
Sbjct: 481 NVTIDGTDVRELNIDYLRNVIGIVQQEPILFNDTIHNNLLLGNPNATREKMIEVCKMANA 540
Query: 1528 NDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREV 1707
+DFI+++P GY T +G+ GVQLSGGQKQR+AIAR LV+ PK+LLLDEATSALD ++E V
Sbjct: 541 HDFIEKMPKGYDTMIGDGGVQLSGGQKQRVAIARTLVREPKVLLLDEATSALDAQSESIV 600
Query: 1708 QGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFK------AGNIVE----SGSHEELMSKQ 1857
Q AL+ A GRTTI++AHRLSTIR D+I F+ AGN E G + +L+ Q
Sbjct: 601 QSALNNASKGRTTIMIAHRLSTIREADKIVFFEKGVIVEAGNHEELVRLGGRYYDLVKAQ 660
Query: 1858 GIFYDMTXXXXXXXXXXEAGKDIEDTISES-----------------------AHSHLXX 1968
D + G+ S A S
Sbjct: 661 AFKPDNDGTVDEIEDEIDLGQSASGLHSRQSSFTSSIRSKMSGAEAFRRGTLGADSFAGG 720
Query: 1969 XXXXXXXXXXXXXIHQLAEEVEECKAPPTSMFKIFK-FNGDKVGWXXXXXXXXXXXXSVT 2145
++A+ +E+ IFK G+ +T
Sbjct: 721 KSTARADAENAAFAEEVAKVMEQDGQISAGYMDIFKNAKGNYTVMFLGFVTGLIRGLELT 780
Query: 2146 PVFALVYAEIFNVY---SLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESL 2316
FAL+ +F + ++ +M + + G F+ F S+ E+L
Sbjct: 781 -AFALLLGWVFEGFQYLNIDNGKMMHRMAMAVIAYGCSGFGCFISQFLSSIFFAIVSENL 839
Query: 2317 TMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVFTRLPVVLASIVTICG 2496
++ R +F+NLL QD +F+D+ H GK + TRL + T+
Sbjct: 840 ALRFRVMSFRNLLYQDASFFDNPAHAPGK--------------LITRLATDAPNCKTVVD 885
Query: 2497 ALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIR 2676
+ R Q+L + + V
Sbjct: 886 S--------------------------------------RMLQVLYALSAIIANIVISFI 907
Query: 2677 TVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVN 2856
HS N F Y + + LK + +QS +++M F LG +
Sbjct: 908 YCHSGNCTHYFTRFYNK------RSELKKGLIEAINYTITQSFMYYMMCFCFALGIRLIY 961
Query: 2857 QQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSG 3036
P DV++ A+ + N + P+ VKA+ AA LLF +I L + G
Sbjct: 962 HGNKSPQDVFQGNIAMLLTAMGVMNAAQYFPEFVKAKTAAGLLFNIIYRKPRTGDLLE-G 1020
Query: 3037 IVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERF 3216
+ GNI NV F+YP R +++G G+TVALVG SG GKST +G+LERF
Sbjct: 1021 SRPEVRGNILFENVKFSYPQRPHQPIMKGLQWTALRGQTVALVGPSGSGKSTCIGMLERF 1080
Query: 3217 YNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVE 3396
Y+ G + IDG +IR L++ LR Q+ +V QEP LF TI ENIC G NV ++I
Sbjct: 1081 YDVTGGTLRIDGQDIRGLSLFHLRTQMALVGQEPRLFAGTIKENICLGLE-NVPMEKINH 1139
Query: 3397 AAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALD 3576
A ++AN + F+ LP G +T VGEKG++LSGGQKQRIAIARALVR P +LLLDEATSALD
Sbjct: 1140 ALELANANRFLANLPAGIETDVGEKGSKLSGGQKQRIAIARALVRDPKILLLDEATSALD 1199
Query: 3577 TESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIY 3756
+ESE+ VQEALD A++GRTC+ IAHRLS+IQNSDVI + G++ E G H +L+ K Y
Sbjct: 1200 SESERAVQEALDRAREGRTCITIAHRLSSIQNSDVIVYIENGRVQEAGNHKQLMSKKGKY 1259
Query: 3757 QKFCETQ 3777
+ + Q
Sbjct: 1260 YELIQKQ 1266
Score = 319 bits (817), Expect = 4e-85
Identities = 196/561 (34%), Positives = 297/561 (52%), Gaps = 17/561 (3%)
Frame = +1
Query: 2146 PVFALVYAEIFNVYSLPADQMQA-------NVYFWCGMFVLMGITFFVGFFTSANCLGRC 2304
PV ++ + N + A Q + NVY + G+ + + IT ++ + C C
Sbjct: 114 PVLTIIAGRVTNAILVYAPQTKQFRNKATENVYIFLGIGIFVTITNYIQYM----CFQHC 169
Query: 2305 GESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASI 2481
+ ++R ++LRQ+ ++D +H +G + T+ +R + +L V+L +
Sbjct: 170 CSRIMAQMRHRYVYSVLRQNAGWFD--KHHSGTIATKLNDSMERIREGIGDKLGVLLRGV 227
Query: 2482 VTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQA 2661
+ ++ + + Y W+ + +++ +E+AG +A ++
Sbjct: 228 AMLVASVVVAYIYEWRLACMLLGVAPTCIGCMSLMARQMTATTVKELGGVEKAGSIAEES 287
Query: 2662 VEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHA-------HTYGAVFAFSQSLIFFMY 2820
+ +RTV + N QE+ E R N K A +G +F F +F
Sbjct: 288 LMGVRTVQAFNGQEEM----VERYRVELNKGRKFAIWKGFWSGLFGGMFFF---WLFAFQ 340
Query: 2821 AAAFYLGSIFVNQQAMQ-PIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLI 2997
F G+ ++ ++ P DV+ + A+ G + + ++ AR+AA ++ I
Sbjct: 341 GCGFLYGAYLLSVGIIKSPGDVFIIVMAMLLGSYFTGLISPHLMVLLNARVAAGSIYETI 400
Query: 2998 EHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHS 3174
+ ID S G + + G + NV F YPTRKD K+L G L I+ G +VALVGHS
Sbjct: 401 DRVPKIDPYSKKGKFLDKVIGRVKFENVHFRYPTRKDAKILNGLNLTIEPGTSVALVGHS 460
Query: 3175 GCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENIC 3354
GCGKST +GLL R Y + G + IDG ++R LNI LR + IV QEP LF+ TI N+
Sbjct: 461 GCGKSTSVGLLTRLYEPEAGNVTIDGTDVRELNIDYLRNVIGIVQQEPILFNDTIHNNLL 520
Query: 3355 YGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRS 3534
G N N T ++++E KMAN H+FI +P GYDT +G+ G QLSGGQKQR+AIAR LVR
Sbjct: 521 LG-NPNATREKMIEVCKMANAHDFIEKMPKGYDTMIGDGGVQLSGGQKQRVAIARTLVRE 579
Query: 3535 PSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVE 3714
P VLLLDEATSALD +SE IVQ AL+ A +GRT ++IAHRLSTI+ +D I +G IVE
Sbjct: 580 PKVLLLDEATSALDAQSESIVQSALNNASKGRTTIMIAHRLSTIREADKIVFFEKGVIVE 639
Query: 3715 KGTHDELIRKSEIYQKFCETQ 3777
G H+EL+R Y + Q
Sbjct: 640 AGNHEELVRLGGRYYDLVKAQ 660
>gi|15232977|ref|NP_189479.1| P-glycoprotein, putative [Arabidopsis
thaliana]
gi|9294573|dbj|BAB02854.1| multidrug resistance p-glycoprotein; ABC
transporter-like protein [Arabidopsis thaliana]
Length = 1240
Score = 715 bits (1846), Expect = 0.0
Identities = 438/1231 (35%), Positives = 678/1231 (54%), Gaps = 14/1231 (1%)
Frame = +1
Query: 94 KLTNYG----IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFV 261
K+ ++G IF + GVD +L+ G + AV G P++ + +
Sbjct: 13 KMKSFGSIRSIFMHADGVDWILMALGLIGAVGDGFITPVVVFIFNTL------------- 59
Query: 262 VGVDNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLR 441
+N G + F + K + L + + +++ C+ ER ++R
Sbjct: 60 -----LNNLGTSSSNNKTFMQTISKNVVALLYVACGSWVICFLEGYCWTRTGERQAARMR 114
Query: 442 QNYLKAILRQQIQWFDKQ--QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGV 615
+ YL+A+LRQ + +FD T ++ ++ D +++ L +K + +AF+A Y V
Sbjct: 115 EKYLRAVLRQDVGYFDLHVTSTSDVITSISSDSLVIQDFLSEKLPNFLMNASAFVASYIV 174
Query: 616 GFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHS 795
F W +T+V F L+++ G +++ + +R E Y AG+IAE+ SS+RTV++
Sbjct: 175 SFILMWRLTIVGFPFIILLLVPGLMYGRALVSISRKIHEQYNEAGSIAEQAISSVRTVYA 234
Query: 796 LNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPT 975
+ + +F AL + G+ + GI +G SN ++ +A WYGS L++N +
Sbjct: 235 FGSENKMIGKFSTALRGSVKLGLRQGLAKGITIG-SNGVTHAIWAFLTWYGSRLVMNHGS 293
Query: 976 FDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILV 1155
G +F V + G SLG +L +L F A A +L VI P ID EG ++
Sbjct: 294 -KGGTVFVVISCITYGGVSLGQSLSNLKYFSEAFVAWERILEVIKRVPDIDSNKKEGQIL 352
Query: 1156 DNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYD 1335
+ MKG++ F V F Y SR + + + L++ AG +ALVG SG GKST+++LLQRFYD
Sbjct: 353 ERMKGEVEFNHVKFTYLSRPETTIFDDLCLKIPAGKTVALVGGSGSGKSTVISLLQRFYD 412
Query: 1336 PTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACK 1515
P G +LIDGV + ++ V+ LR Q+G+VSQEPVLF +I ENI G E A+ D+VVEA K
Sbjct: 413 PIAGEILIDGVSIDKLQVNWLRSQMGLVSQEPVLFATSITENILFGKEDASLDEVVEAAK 472
Query: 1516 MANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEA 1695
+NA+ FI + P GY T+VGE+GVQ+SGGQKQRIAIARA++K+PKILLLDEATSALD+E+
Sbjct: 473 ASNAHTFISQFPLGYKTQVGERGVQMSGGQKQRIAIARAIIKSPKILLLDEATSALDSES 532
Query: 1696 EREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSK-QGIFYD 1872
ER VQ +LD A GRTTI++AHRLSTIRN D I V G IVE+GSHEEL+ + G +
Sbjct: 533 ERVVQESLDNASIGRTTIVIAHRLSTIRNADVICVIHNGQIVETGSHEELLKRIDGQYTS 592
Query: 1873 MTXXXXXXXXXXEAGKDIEDTISE--SAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKA 2046
+ ++ T + S + +++ +
Sbjct: 593 LVSLQQMENEESNVNINVSVTKDQVMSLSKDFKYSQHNSIGSTSSSIVTNVSDLIPNDNQ 652
Query: 2047 PPTSMF-KIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPA-DQMQANV 2220
P F ++ N + + PV A + +V+ L + DQ++
Sbjct: 653 PLVPSFTRLMVMNRPEWKHALYGCLSAALVGVLQPVSAYSAGSVISVFFLTSHDQIKEKT 712
Query: 2221 YFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTG 2400
+ +FV + I F+ + GE LT ++R + +L ++ ++D + +G
Sbjct: 713 RIYVLLFVGLAIFSFLVNISQHYGFAYMGEYLTKRIREQMLSKILTFEVNWFDIDDNSSG 772
Query: 2401 KLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGG 2577
+C+R A DA VR V R+ +++ +I + A IG W+ +
Sbjct: 773 AICSRLAKDANVVRSMVGDRMSLLVQTISAVIIACIIGLVIAWRLAIVMISVQPLIVVCF 832
Query: 2578 YFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNL 2757
Y + + + ++ +E+ K+A++AV +IRT+ + + QE+ + P ++
Sbjct: 833 YTQRVLLKSLSEKASKAQDESSKLAAEAVSNIRTITAFSSQERIIKLLKKVQEGPRRESV 892
Query: 2758 KHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTT 2937
+ G V S+SLI A F+ G + + + +F G++I +
Sbjct: 893 HRSWLAGIVLGTSRSLITCTSALNFWYGGRLIADGKIVSKAFFEIFLIFVTTGRVIADAG 952
Query: 2938 SFIPDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTKV 3114
+ D+ + A +F +++ T I+ + G + + I G I+ NV F YPTR D +
Sbjct: 953 TMTTDLARGLDAVGSVFAVLDRCTTIEPKNPDGYVAEKIKGQITFLNVDFAYPTRPDVVI 1012
Query: 3115 LQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQ 3294
+ F+++I GK+ A+VG SG GKSTI+GL+ERFY+ KG + IDG +IR+ ++ SLR+
Sbjct: 1013 FENFSIEIDEGKSTAIVGTSGSGKSTIIGLIERFYDPLKGTVKIDGRDIRSYHLRSLRKY 1072
Query: 3295 VCIVSQEPTLFDCTIGENICY-GTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEK 3471
+ +VSQEP LF TI ENI Y GT+ + EI+EAAK AN H+FI L +GYDT+ G+K
Sbjct: 1073 ISLVSQEPMLFAGTIRENIMYGGTSDKIDESEIIEAAKAANAHDFITSLSNGYDTNCGDK 1132
Query: 3472 GTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAH 3651
G QLSGGQKQRIAIARA++++PSVLLLDEATSALD++SE++VQ+AL+ GRT ++IAH
Sbjct: 1133 GVQLSGGQKQRIAIARAVLKNPSVLLLDEATSALDSKSERVVQDALERVMVGRTSIMIAH 1192
Query: 3652 RLSTIQNSDVIAIVSEGKIVEKGTHDELIRK 3744
RLSTIQN D+I ++ +GKIVE GTH L+ K
Sbjct: 1193 RLSTIQNCDMIVVLGKGKIVESGTHSSLLEK 1223
>gi|15232975|ref|NP_189477.1| ABC transporter family protein
[Arabidopsis thaliana]
Length = 1158
Score = 707 bits (1826), Expect = 0.0
Identities = 420/1139 (36%), Positives = 648/1139 (56%), Gaps = 12/1139 (1%)
Frame = +1
Query: 364 VLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQ--QTGNLTARLTDDLE 537
V+ F Y C+ ER K+R+ YL+A+LRQ + +FD T ++ ++ D
Sbjct: 10 VICFLEGY----CWTRTGERQAAKMRERYLRAVLRQDVGYFDLHVTSTSDIITSVSSDSL 65
Query: 538 RVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRT 717
+++ L +K ++ +AF+ Y VGF W +T+V F L+++ G +++ +
Sbjct: 66 VIQDFLSEKLPNILMNASAFVGSYIVGFMLLWRLTIVGFPFIILLLIPGLMYGRALIGIS 125
Query: 718 RVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVG 897
R +E Y AG+IAE+ SS+RTV++ K+ +++F +AL+ + G+ + GI +G
Sbjct: 126 RKIREEYNEAGSIAEQAISSVRTVYAFVSEKKMIEKFSDALQGSVKLGLRQGLAKGIAIG 185
Query: 898 FSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTAR 1077
SN +Y+ + WYGS +++N + G + TV V G T+LG AL +L F A
Sbjct: 186 -SNGIVYAIWGFLTWYGSRMVMNYG-YKGGTVSTVTVCVTFGGTALGQALSNLKYFSEAF 243
Query: 1078 GAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKA 1257
A + ++I P ID +L G +++ ++G++ F +V +YPSR + + + L++ +
Sbjct: 244 VAGERIQKMIKRVPDIDSDNLNGHILETIRGEVEFNNVKCKYPSRPETLIFDDLCLKIPS 303
Query: 1258 GDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVL 1437
G +ALVG SG GKST+++LLQRFYDP +G +LID V + + V LR Q+G+VSQEP L
Sbjct: 304 GKTVALVGGSGSGKSTVISLLQRFYDPNEGDILIDSVSINNMQVKWLRSQMGMVSQEPSL 363
Query: 1438 FDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRI 1617
F +I ENI G E A+ D+VVEA K +NA++FI + P GY T+VGE+GV +SGGQKQRI
Sbjct: 364 FATSIKENILFGKEDASFDEVVEAAKASNAHNFISQFPHGYQTQVGERGVHMSGGQKQRI 423
Query: 1618 AIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIF 1797
AIARAL+K+P ILLLDEATSALD E+ER VQ ALD A GRTTI++AHRLSTIRN D I
Sbjct: 424 AIARALIKSPIILLLDEATSALDLESERVVQEALDNASVGRTTIVIAHRLSTIRNADIIC 483
Query: 1798 VFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXX--EAGKDIEDTISESAHSHLXXX 1971
V G IVE+GSH++LM G + + +++ S + L
Sbjct: 484 VLHNGCIVETGSHDKLMEIDGKYTSLVRLQQMKNEESCDNTSVGVKEGRVSSLRNDLDYN 543
Query: 1972 XXXXXXXXXXXXIHQLAEEVEECKAPPTSMFK-IFKFNGDKVGWXXXXXXXXXXXXSVTP 2148
+ L++ + + K P FK + N + +V P
Sbjct: 544 PRDLAHSMSSSIVTNLSDSIPQDKKPLVPSFKRLMAMNRPEWKHALCGCLSASLGGAVQP 603
Query: 2149 VFALVYAEIFNVYSLP-ADQMQANVYFWCGMFVLMGITFFVGFFTSAN---CLGRCGESL 2316
++A + +V+ L +Q++ N + +F G+ F FFTS + GE L
Sbjct: 604 IYAYSSGLMISVFFLTNHEQIKENTRIYVLLF--FGLALFT-FFTSISQQYSFSYMGEYL 660
Query: 2317 TMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTIC 2493
T ++R + +L ++ ++D+ + +G +C+R A DA VR V R+ +++ +I T+
Sbjct: 661 TKRIREQMLSKILTFEVNWFDEEENSSGAICSRLAKDANVVRSLVGERMSLLVQTISTVM 720
Query: 2494 GALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHI 2673
A IG W+ + Y + + + +E+ K+A++AV +I
Sbjct: 721 VACTIGLVIAWRFTIVMISVQPVIIVCYYIQRVLLKNMSKKAIIAQDESSKLAAEAVSNI 780
Query: 2674 RTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFV 2853
RT+ + + QE+ P + + + G + +QSLI A F+ G +
Sbjct: 781 RTITTFSSQERIMKLLERVQEGPRRESARQSWLAGIMLGTTQSLITCTSALNFWYGGKLI 840
Query: 2854 NQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDS 3033
M + +F G+ I + D+ K + +F +++ T I+ +
Sbjct: 841 ADGKMVSKAFFELFLIFKTTGRAIAEAGTMTTDLAKGSNSVDSVFTVLDRRTTIEPENPD 900
Query: 3034 G-IVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLE 3210
G I++ I G I+ NV F YPTR + + F+++I GK+ A+VG S GKST++GL+E
Sbjct: 901 GYILEKIKGQITFLNVDFAYPTRPNMVIFNNFSIEIHEGKSTAIVGPSRSGKSTVIGLIE 960
Query: 3211 RFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRN-VTYQE 3387
RFY+ +G++ IDG +IR+ ++ SLR+ + +VSQEPTLF TI ENI YG N + E
Sbjct: 961 RFYDPLQGIVKIDGRDIRSYHLRSLRQHMSLVSQEPTLFAGTIRENIMYGRASNKIDESE 1020
Query: 3388 IVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATS 3567
I+EA K AN H FI L DGYDT+ G++G QLSGGQKQRIAIAR ++++PS+LLLDEATS
Sbjct: 1021 IIEAGKTANAHEFITSLSDGYDTYCGDRGVQLSGGQKQRIAIARTILKNPSILLLDEATS 1080
Query: 3568 ALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRK 3744
ALD++SE++VQ+AL+ G+T +VIAHRLSTIQN D IA++ +GK+VE GTH L+ K
Sbjct: 1081 ALDSQSERVVQDALEHVMVGKTSVVIAHRLSTIQNCDTIAVLDKGKVVESGTHASLLAK 1139
Score = 342 bits (878), Expect = 3e-92
Identities = 204/579 (35%), Positives = 322/579 (55%), Gaps = 11/579 (1%)
Frame = +1
Query: 151 ITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEV 330
+ G ++A + GA P+ A G M +VF + ++
Sbjct: 589 LCGCLSASLGGAVQPIYAYSSGLMISVFFLTNH--------------------EQIKENT 628
Query: 331 VKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQ--TG 504
Y + + L + FFTS Q F E L ++R+ L IL ++ WFD+++ +G
Sbjct: 629 RIYVLLFFGLALFTFFTSISQQYSFSYMGEYLTKRIREQMLSKILTFEVNWFDEEENSSG 688
Query: 505 NLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLS- 681
+ +RL D VR +G++ +LLVQ + + +G +W T+VM+ P+I++
Sbjct: 689 AICSRLAKDANVVRSLVGERMSLLVQTISTVMVACTIGLVIAWRFTIVMISVQPVIIVCY 748
Query: 682 --GAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQ 855
+ K+M+ + + Q+ + +A E S+IRT+ + + +R + E R+
Sbjct: 749 YIQRVLLKNMSKKAIIAQDE---SSKLAAEAVSNIRTITTFSSQERIMKLLERVQEGPRR 805
Query: 856 TGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSL 1035
+ GI +G + + + AL FWYG LI D ++ FF + +
Sbjct: 806 ESARQSWLAGIMLGTTQSLITCTSALNFWYGGKLIA-----DGKMVSKAFFELFLIFKTT 860
Query: 1036 GGALPHLASFGT--ARGAAS--TVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRY 1203
G A+ + T A+G+ S +V V++ I+P + +G +++ +KG I+F +V F Y
Sbjct: 861 GRAIAEAGTMTTDLAKGSNSVDSVFTVLDRRTTIEPENPDGYILEKIKGQITFLNVDFAY 920
Query: 1204 PSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREV 1383
P+R ++ + S+E+ G A+VG S GKST++ L++RFYDP +G V IDG D+R
Sbjct: 921 PTRPNMVIFNNFSIEIHEGKSTAIVGPSRSGKSTVIGLIERFYDPLQGIVKIDGRDIRSY 980
Query: 1384 NVHSLREQIGIVSQEPVLFDGTIYENIKMG--NEHATHDQVVEACKMANANDFIKRLPDG 1557
++ SLR+ + +VSQEP LF GTI ENI G + +++EA K ANA++FI L DG
Sbjct: 981 HLRSLRQHMSLVSQEPTLFAGTIRENIMYGRASNKIDESEIIEAGKTANAHEFITSLSDG 1040
Query: 1558 YGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAG 1737
Y T G++GVQLSGGQKQRIAIAR ++KNP ILLLDEATSALD+++ER VQ AL+ G
Sbjct: 1041 YDTYCGDRGVQLSGGQKQRIAIARTILKNPSILLLDEATSALDSQSERVVQDALEHVMVG 1100
Query: 1738 RTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSK 1854
+T++++AHRLSTI+N D I V G +VESG+H L++K
Sbjct: 1101 KTSVVIAHRLSTIQNCDTIAVLDKGKVVESGTHASLLAK 1139
Score = 313 bits (802), Expect = 2e-83
Identities = 185/505 (36%), Positives = 284/505 (55%), Gaps = 2/505 (0%)
Frame = +1
Query: 2275 FTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVR-YVF 2451
F C R GE K+R + +LRQD+ ++D T + T ++D+ ++ ++
Sbjct: 13 FLEGYCWTRTGERQAAKMRERYLRAVLRQDVGYFDLHVTSTSDIITSVSSDSLVIQDFLS 72
Query: 2452 TRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLL 2631
+LP +L + G+ +GF W+ + G + G + +
Sbjct: 73 EKLPNILMNASAFVGSYIVGFMLLWRLTIVGFPFIILLLIPGLMYGRALIGISRKIREEY 132
Query: 2632 EEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIF 2811
EAG +A QA+ +RTV++ +++ + + L+ L+ G S +++
Sbjct: 133 NEAGSIAEQAISSVRTVYAFVSEKKMIEKFSDALQGSVKLGLRQGLAKGIAIG-SNGIVY 191
Query: 2812 FMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFY 2991
++ + GS V + V V ++F G +G S + +A +A +
Sbjct: 192 AIWGFLTWYGSRMVMNYGYKGGTVSTVTVCVTFGGTALGQALSNLKYFSEAFVAGERIQK 251
Query: 2992 LIEHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVG 3168
+I+ IDS + +G I++ I G + NV YP+R +T + L I +GKTVALVG
Sbjct: 252 MIKRVPDIDSDNLNGHILETIRGEVEFNNVKCKYPSRPETLIFDDLCLKIPSGKTVALVG 311
Query: 3169 HSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGEN 3348
SG GKST++ LL+RFY+ ++G I+ID +I N+ + LR Q+ +VSQEP+LF +I EN
Sbjct: 312 GSGSGKSTVISLLQRFYDPNEGDILIDSVSINNMQVKWLRSQMGMVSQEPSLFATSIKEN 371
Query: 3349 ICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALV 3528
I +G + ++ E+VEAAK +N HNFI P GY T VGE+G +SGGQKQRIAIARAL+
Sbjct: 372 ILFG-KEDASFDEVVEAAKASNAHNFISQFPHGYQTQVGERGVHMSGGQKQRIAIARALI 430
Query: 3529 RSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKI 3708
+SP +LLLDEATSALD ESE++VQEALD A GRT +VIAHRLSTI+N+D+I ++ G I
Sbjct: 431 KSPIILLLDEATSALDLESERVVQEALDNASVGRTTIVIAHRLSTIRNADIICVLHNGCI 490
Query: 3709 VEKGTHDELIRKSEIYQKFCETQRI 3783
VE G+HD+L+ Y Q++
Sbjct: 491 VETGSHDKLMEIDGKYTSLVRLQQM 515
>gi|7493911|pir||T30882 multidrug resistance protein 1 - Aspergillus
flavus
gi|2673947|gb|AAB88655.1| multidrug resistance protein 1 [Aspergillus
flavus]
gi|2673949|gb|AAB88656.1| multidrug resistance protein 1 [Aspergillus
flavus]
Length = 1307
Score = 706 bits (1823), Expect = 0.0
Identities = 441/1270 (34%), Positives = 660/1270 (51%), Gaps = 46/1270 (3%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNP 285
+GI+ Y D+ +L +AA+ GA PL ++ G +T+ F
Sbjct: 48 FGIYRYATRWDVAILFGSALAAIAGGAALPLFTVLFGRLTSTFQDIATHR---------- 97
Query: 286 EGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAIL 465
I+ D F+ E+ K +Y++ LG F Y+ F + +V ++R Y +AIL
Sbjct: 98 -----ITYDHFHHELTKNVVYFIYLGAAEFVAIYLATVGFIYTGDHVVQQIRVEYFQAIL 152
Query: 466 RQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTL 645
RQ I +FD G +T R+T D +++G+ +K L + + F+ + + + +W + L
Sbjct: 153 RQNIAFFDTLGAGEITTRITADTNLIQDGISEKVGLALTGLSTFVTAFIIAYIKNWKLAL 212
Query: 646 VMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDR 825
+ ++L+ S M ++ E ++AE+ SIRTV + N + +
Sbjct: 213 ICSASLLALLLTMGGCSTLMLIFSKKALEYQGRGASMAEDILDSIRTVAAFNAQETLARK 272
Query: 826 FYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIIND-PTFDRGLIFTV 1002
+ + L+ G+ I VG MY +Y L FW GS ++ G + T+
Sbjct: 273 YESHLKDAEGPGMKSKVIFAIMVGALLCIMYLNYGLGFWMGSRFLVEGISNIKAGDVLTI 332
Query: 1003 FFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISF 1182
A++ GS +LG P+ + A AAS + I+ +D S +G ++ ++G+I
Sbjct: 333 MMAIILGSYNLGNVAPNGQALSDAVAAASKLYGTIDRQSPLDALSDQGKTLEFVRGNIVL 392
Query: 1183 KDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLID 1362
+++ YPSR ++ V +S + AG A VG SG GKSTI++LL+RFYDP G +++D
Sbjct: 393 QNIRHVYPSRPEVTVAHDLSCYIPAGKTTAFVGPSGSGKSTIISLLERFYDPVAGTIMLD 452
Query: 1363 GVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMG------NEHATHD---QVVEACK 1515
G D++ +N+ LR+Q+ +VSQEP LF TI ENI+ G + +T++ +V A +
Sbjct: 453 GHDIQTLNLRWLRQQMSLVSQEPRLFATTIAENIRYGIIGSRFEKESTYEIRKRVEAAAR 512
Query: 1516 MANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEA 1695
MANA+DFI LP+GY T + + LSGGQKQRIAIARA++K+PKILLLDEATSALDT++
Sbjct: 513 MANAHDFIMALPNGYDTNI--ESFSLSGGQKQRIAIARAIIKDPKILLLDEATSALDTKS 570
Query: 1696 EREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM 1875
E+ VQ ALD+A GRTTI++AHRLSTI+ I V G IVE G HE LM ++GI+ DM
Sbjct: 571 EKLVQAALDKASKGRTTIVIAHRLSTIQKAYNIIVLANGQIVEQGPHEHLMDRRGIYCDM 630
Query: 1876 TXXXXXXXXXXEAGK------------------------------DIEDTISESAHSHLX 1965
K DI +S+ A S +
Sbjct: 631 VEAHEIKKRYSRYSKRYSQLLTNLSPKHNPMTFFFDKDYPGDDESDIYSILSDDA-SDIG 689
Query: 1966 XXXXXXXXXXXXXXIHQLAEEVEECKAPPTSMFK-IFKFNGDKVGWXXXXXXXXXXXXSV 2142
+ L + V+E ++FK + FN + + +
Sbjct: 690 LHTGEKQRPVSRMSLSHLMQPVKEEAYSFWTLFKFLASFNRPEWPFLLLGLCASILAGGI 749
Query: 2143 TPVFALVYAEIFNVYSLPA---DQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGES 2313
P A+++A+ + SLP +++ + FWC MF+++GI V + E
Sbjct: 750 QPSQAVLFAKAVSTLSLPPLEYPKLRHDANFWCLMFLMIGIVSLVLYSVQGTLFAYSSEK 809
Query: 2314 LTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVF-TRLPVVLASIVTI 2490
+ + R +AF+ +L QDI+F+D + TG L + + + L +L V +
Sbjct: 810 MVYRARSQAFRVILHQDISFFDQQENTTGALTATLSAGTKELTGISGVTLGTILIVSVNL 869
Query: 2491 CGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEH 2670
+LG+ GW+ M G+ + M Q R + +E+ A +A
Sbjct: 870 VASLGVALVIGWKLALVCISAVPALLMCGFVRVWMLERFQRRAKKAYQESASSACEAASA 929
Query: 2671 IRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIF 2850
IRTV SL + + +Y LR +++ ++A SQ+L FF A F+ G
Sbjct: 930 IRTVVSLTMETEALQSYQAQLRRQLKSDILPIVKSSLLYASSQALPFFCMALGFWYGGSL 989
Query: 2851 VNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSD 3030
+ Y F + F Q G S PD+ KA+ AA L T S S
Sbjct: 990 LGHGEYSLFQFYVCFSEVIFGAQAAGTVFSHAPDMGKAKHAAREFKRLFSSDTMHASRSK 1049
Query: 3031 SGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLE 3210
V + G + R+V F YP+R + +L+ L IK G+ VALVG SG GKST + LLE
Sbjct: 1050 GVPVTSMRGLVEFRDVSFRYPSRLEQPILRHLNLTIKPGQFVALVGASGSGKSTTIALLE 1109
Query: 3211 RFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNR-NVTYQE 3387
RFY+ KG + +DG NI L +SS R + ++SQEPTLF TI ENI G+N +VT
Sbjct: 1110 RFYDPLKGGVYVDGKNIITLEMSSYRSHLALISQEPTLFQGTIRENILLGSNTPHVTDDF 1169
Query: 3388 IVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATS 3567
+V+A K ANI++FIL LP G++T VG KG LSGGQKQRIAIARAL+R+P +LLLDEATS
Sbjct: 1170 LVKACKDANIYDFILSLPQGFNTIVGNKGGMLSGGQKQRIAIARALIRNPKILLLDEATS 1229
Query: 3568 ALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKS 3747
ALD+ESEK+VQ ALDAA +GRT + +AHRLSTIQ +D+I ++ +G++VE GTH EL+RK
Sbjct: 1230 ALDSESEKVVQAALDAAARGRTTIAVAHRLSTIQRADLIYVLDQGEVVESGTHRELLRKK 1289
Query: 3748 EIYQKFCETQ 3777
Y + Q
Sbjct: 1290 GRYYELVHLQ 1299
Score = 317 bits (812), Expect = 1e-84
Identities = 201/532 (37%), Positives = 299/532 (55%), Gaps = 17/532 (3%)
Frame = +1
Query: 2239 FVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRF 2418
F+ +G FV + + G+ + ++R E F+ +LRQ+IAF+D L G G++ TR
Sbjct: 114 FIYLGAAEFVAIYLATVGFIYTGDHVVQQIRVEYFQAILRQNIAFFDTL--GAGEITTRI 171
Query: 2419 ATDAPNVRY-VFTRLPVVLASIVTICGALGIGFYYGWQXXX--XXXXXXXXXXMGGYFEM 2589
D ++ + ++ + L + T A I + W+ MGG +
Sbjct: 172 TADTNLIQDGISEKVGLALTGLSTFVTAFIIAYIKNWKLALICSASLLALLLTMGGCSTL 231
Query: 2590 QMRFGKQIRDTQLLEEAGKVASQA---VEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLK 2760
+ F K+ LE G+ AS A ++ IRTV + N QE Y +L++ +K
Sbjct: 232 MLIFSKKA-----LEYQGRGASMAEDILDSIRTVAAFNAQETLARKYESHLKDAEGPGMK 286
Query: 2761 HAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQ--QAMQPIDVYRVFFAISFCGQMIGNT 2934
+ + +++ Y F++GS F+ + ++ DV + AI +GN
Sbjct: 287 SKVIFAIMVGALLCIMYLNYGLGFWMGSRFLVEGISNIKAGDVLTIMMAIILGSYNLGNV 346
Query: 2935 TSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITGNISIRNVFFNYPTRKDTK 3111
+ A AAS L+ I+ +P+D+LSD G ++ + GNI ++N+ YP+R +
Sbjct: 347 APNGQALSDAVAAASKLYGTIDRQSPLDALSDQGKTLEFVRGNIVLQNIRHVYPSRPEVT 406
Query: 3112 VLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLRE 3291
V + I AGKT A VG SG GKSTI+ LLERFY+ G IM+DG +I+ LN+ LR+
Sbjct: 407 VAHDLSCYIPAGKTTAFVGPSGSGKSTIISLLERFYDPVAGTIMLDGHDIQTLNLRWLRQ 466
Query: 3292 QVCIVSQEPTLFDCTIGENICYGT-----NRNVTYQ---EIVEAAKMANIHNFILGLPDG 3447
Q+ +VSQEP LF TI ENI YG + TY+ + AA+MAN H+FI+ LP+G
Sbjct: 467 QMSLVSQEPRLFATTIAENIRYGIIGSRFEKESTYEIRKRVEAAARMANAHDFIMALPNG 526
Query: 3448 YDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQG 3627
YDT++ + LSGGQKQRIAIARA+++ P +LLLDEATSALDT+SEK+VQ ALD A +G
Sbjct: 527 YDTNI--ESFSLSGGQKQRIAIARAIIKDPKILLLDEATSALDTKSEKLVQAALDKASKG 584
Query: 3628 RTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRI 3783
RT +VIAHRLSTIQ + I +++ G+IVE+G H+ L+ + IY E I
Sbjct: 585 RTTIVIAHRLSTIQKAYNIIVLANGQIVEQGPHEHLMDRRGIYCDMVEAHEI 636
>gi|27368845|emb|CAD59580.1| MDR-like ABC transporter [Oryza sativa
(japonica cultivar-group)]
Length = 1349
Score = 704 bits (1817), Expect = 0.0
Identities = 434/1276 (34%), Positives = 677/1276 (53%), Gaps = 49/1276 (3%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F + G+D +L+ GT+ A++HG TVFLR F VD+
Sbjct: 84 LFSFGDGLDYVLMTLGTLGALVHGCSL-----------TVFLRF----FADLVDSFGSHA 128
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
P D VVKY Y+LV+G ++ +S+ +I+C+ ER ++R YL A L Q
Sbjct: 129 AHP---DTMLRLVVKYAFYFLVVGAAIWASSWAEISCWMWTGERQSTRMRIRYLHAALHQ 185
Query: 472 QIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLV 648
+ +FD +T ++ + D V++ + +K L+ A F++G+ VGF +W + LV
Sbjct: 186 DVSFFDTDVRTSDVIHAINADAVVVQDAISEKLGNLIHYLATFVSGFVVGFTAAWQLALV 245
Query: 649 MMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRF 828
+ PLI + G + ++A + Q+ + A IAE+ + IR V S G +R + +
Sbjct: 246 TLAVVPLIAVIGGLSAAALAKLSSRSQDALSDASGIAEQALAQIRIVQSFVGEERVMRAY 305
Query: 829 YNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFF 1008
AL V ++ G GIG+G + ++ YAL WYG L+ T + GL F
Sbjct: 306 SAALAVAQRIGYRSGFAKGIGLGGTYFTVFCCYALLLWYGGHLVRRAHT-NGGLAIATMF 364
Query: 1009 AVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKD 1188
+V+ G +LG + P +A+F AR AA+ + R++ P ++ G+ ++ + G + +D
Sbjct: 365 SVMIGGLALGQSAPSMAAFAKARVAAAKIFRMMEHKPSMEREG--GVELEAVTGRVELRD 422
Query: 1189 VHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGV 1368
V F YPSR D+ +L+G+SL + AG IALVGSSG GKST+V+L++RFY+P G +L+DG
Sbjct: 423 VEFSYPSRPDVGILRGLSLSVPAGKTIALVGSSGSGKSTVVSLIERFYEPNAGTILLDGH 482
Query: 1369 DLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRL 1548
DLR++N+ LR QIG+VSQEP LF TI EN+ +G + AT +++ EA ++ANA+ FI +L
Sbjct: 483 DLRDLNLRWLRRQIGLVSQEPALFATTIRENLLLGRDGATQEELEEAARVANAHSFIVKL 542
Query: 1549 PDGYGT-------------------RVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEA 1671
PD Y T +VGE+G+QLSGGQKQRIAIARA+++NP ILLLDEA
Sbjct: 543 PDAYNTQARPGGNQWVAFERCSELVQVGERGLQLSGGQKQRIAIARAMLRNPAILLLDEA 602
Query: 1672 TSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMS 1851
TSALD+E+E+ VQ ALD+ GRTT+++AHRLSTIR D + V + G I E G+H+ELM+
Sbjct: 603 TSALDSESEKLVQEALDRFMIGRTTLVIAHRLSTIRKADLVAVLQGGAISEVGTHDELMA 662
Query: 1852 KQGIFY-------------DMTXXXXXXXXXXEAGKDIEDTI-------SESAHSHLXXX 1971
+ Y + A + I S +S
Sbjct: 663 RGDGTYARLIRMQEQAHEAALVAARRSSARPSSARNSVSSPIITRNSSYGRSPYSRRLSD 722
Query: 1972 XXXXXXXXXXXXIHQLAEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPV 2151
Q ++ + +S +++ K N + G+ S + +
Sbjct: 723 ADFITGLGLGVDSKQ-QQQQHYFRVQASSFWRLAKMNSPEWGYALVASLGSMVCGSFSAI 781
Query: 2152 FALVYAEIFNVYSLP-ADQMQANVYFWCGMFVLMGITFFVGFFTSANCL--GRCGESLTM 2322
FA V + + +VY P A M + +C ++L+G++ F + L GE+LT
Sbjct: 782 FAYVLSAVLSVYYAPDAAYMDRQIAKYC--YLLIGMSSAALLFNTVQHLFWDTVGENLTK 839
Query: 2323 KLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGA 2499
++R +LR +IA++D + + ++ R A DA NVR + R+ +++ + + A
Sbjct: 840 RVRERMLAAVLRNEIAWFDMEDNSSARIAARLALDAQNVRSAIGDRISIIVQNSALMLVA 899
Query: 2500 LGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRT 2679
GF W+ + G + A ++A +AV ++RT
Sbjct: 900 CTAGFVLQWRLALVLLAVFPLVVAATVLQKMFLKGFSGDLERAHARATQIAGEAVANVRT 959
Query: 2680 VHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQ 2859
V + + + + L P G+ + +Q L++ YA + + V
Sbjct: 960 VAAFGSEAKIVGLFEANLAGPLRRCFWKGQIAGSGYGVAQFLLYASYALGLWYAAWLVKH 1019
Query: 2860 QAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPI--DSLSDS 3033
RVF + T + PD VK A +F ++ T I D + +
Sbjct: 1020 GVSDFSKTIRVFMVLMVSANGAAETLTLAPDFVKGGRAMQAVFEAMDRRTEIEPDDVDAA 1079
Query: 3034 GIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLER 3213
+ + G + +++V F YP+R + +V + +L +AG+T+ALVG SGCGKS+++ L++R
Sbjct: 1080 AVPERPRGEVELKHVDFAYPSRPEVQVFRDLSLRARAGRTLALVGASGCGKSSVLALVQR 1139
Query: 3214 FYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIV 3393
FY + G +++DG ++R N+ SLR + +V QEP LF TI +NI YG T E+V
Sbjct: 1140 FYEPNSGRVLLDGRDLRKFNLRSLRRAMALVPQEPFLFAATIHDNIAYG-REGATEAEVV 1198
Query: 3394 EAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSAL 3573
EAA AN H FI LP+GY T VGE+G QLSGGQ+QRIAIARALV+ +LLLDEATSAL
Sbjct: 1199 EAATAANAHKFISALPEGYGTLVGERGVQLSGGQRQRIAIARALVKQAPILLLDEATSAL 1258
Query: 3574 DTESEKIVQEAL-DAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELI--RK 3744
D ESE+ VQEAL ++ GRT +V+AHRL+T++N+ IA++ +GK+ E+G+H L+
Sbjct: 1259 DAESERSVQEALASSSGSGRTTIVVAHRLATVRNAHTIAVIDDGKVAEQGSHSHLLNHHP 1318
Query: 3745 SEIYQKFCETQRIVES 3792
Y + + QR+ S
Sbjct: 1319 DGCYARMLQLQRLSHS 1334
Score = 314 bits (805), Expect = 9e-84
Identities = 204/595 (34%), Positives = 310/595 (51%), Gaps = 27/595 (4%)
Frame = +1
Query: 2047 PPTSMFKIFKFNG--DKVGWXXXXXXXXXXXXSVTPVFALVYAEI---FNVYSLPADQMQ 2211
PP ++F F D V S+T VF +A++ F ++ D M
Sbjct: 77 PPAPFRQLFSFGDGLDYVLMTLGTLGALVHGCSLT-VFLRFFADLVDSFGSHAAHPDTML 135
Query: 2212 ANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYD-DLR 2388
V + F+++G + + +C GE + ++R L QD++F+D D+R
Sbjct: 136 RLVVKYAFYFLVVGAAIWASSWAEISCWMWTGERQSTRMRIRYLHAALHQDVSFFDTDVR 195
Query: 2389 HGTGKLCTRFATDAPNVRYVFT-RLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXX 2565
T + DA V+ + +L ++ + T +GF WQ
Sbjct: 196 --TSDVIHAINADAVVVQDAISEKLGNLIHYLATFVSGFVVGFTAAWQLALVTLAVVPLI 253
Query: 2566 XMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPF 2745
+ G R L +A +A QA+ IR V S +E+ Y L
Sbjct: 254 AVIGGLSAAALAKLSSRSQDALSDASGIAEQALAQIRIVQSFVGEERVMRAYSAALAVAQ 313
Query: 2746 NTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMI 2925
+ G + +F YA + G V + F++ G +
Sbjct: 314 RIGYRSGFAKGIGLGGTYFTVFCCYALLLWYGGHLVRRAHTNGGLAIATMFSVMIGGLAL 373
Query: 2926 GNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGI-VKPITGNISIRNVFFNYPTRK 3102
G + + KAR+AA+ +F ++EH ++ + G+ ++ +TG + +R+V F+YP+R
Sbjct: 374 GQSAPSMAAFAKARVAAAKIFRMMEHKPSMER--EGGVELEAVTGRVELRDVEFSYPSRP 431
Query: 3103 DTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISS 3282
D +L+G +L + AGKT+ALVG SG GKST++ L+ERFY + G I++DG ++R+LN+
Sbjct: 432 DVGILRGLSLSVPAGKTIALVGSSGSGKSTVVSLIERFYEPNAGTILLDGHDLRDLNLRW 491
Query: 3283 LREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTH- 3459
LR Q+ +VSQEP LF TI EN+ G + T +E+ EAA++AN H+FI+ LPD Y+T
Sbjct: 492 LRRQIGLVSQEPALFATTIRENLLLGRD-GATQEELEEAARVANAHSFIVKLPDAYNTQA 550
Query: 3460 ------------------VGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTES 3585
VGE+G QLSGGQKQRIAIARA++R+P++LLLDEATSALD+ES
Sbjct: 551 RPGGNQWVAFERCSELVQVGERGLQLSGGQKQRIAIARAMLRNPAILLLDEATSALDSES 610
Query: 3586 EKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSE 3750
EK+VQEALD GRT LVIAHRLSTI+ +D++A++ G I E GTHDEL+ + +
Sbjct: 611 EKLVQEALDRFMIGRTTLVIAHRLSTIRKADLVAVLQGGAISEVGTHDELMARGD 665
>gi|7442649|pir||T06165 multidrug resistance protein 1 homolog -
barley
gi|2292907|emb|CAA71179.1| P-glycoprotein homologue [Hordeum vulgare
subsp. vulgare]
Length = 1232
Score = 701 bits (1810), Expect = 0.0
Identities = 425/1233 (34%), Positives = 671/1233 (53%), Gaps = 9/1233 (0%)
Frame = +1
Query: 109 GIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPE 288
G+F + VD++L+ GT+ A+ G LL I + NS +G + +
Sbjct: 20 GLFKFADRVDVVLMALGTLGAIGDGCSTNLLLIFASDV-------MNS---LGRGHAQQQ 69
Query: 289 GLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILR 468
G + F ++ K C+ ++ L + + ++ C+ +ER V ++R YL+AILR
Sbjct: 70 GSATSA--HFMHDIEKSCLNFVYLAFAILVVASMEGYCWSRTSERQVLRIRHLYLEAILR 127
Query: 469 QQIQWFDKQQ--TGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMT 642
Q++ +FD Q+ T + ++ D ++E L +K L + F++G ++SW +
Sbjct: 128 QEVAFFDSQEATTSEIINSISKDASLIQEVLSEKVPLFLMHSTVFVSGLAFSTYFSWRLA 187
Query: 643 LVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELD 822
LV L+++ G K + +R + YA A ++ E+ SI+TV+S K +
Sbjct: 188 LVSYPLVLLLIIPGLIYGKYLLYLSRESRREYAKANSLVEQALGSIKTVYSFTAEKGIIQ 247
Query: 823 RFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTV 1002
R+ L+ GI + G+ VGF+ L ++ +A WYGS L++ G I+
Sbjct: 248 RYTAILDKTINLGIKQGIAKGLAVGFTGLS-FAIWAFLAWYGSRLVMYHHE-SGGRIYAA 305
Query: 1003 FFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISF 1182
+ + G SLG ALP L F A AA+ +L IN P+I+ +G+++D ++G+I F
Sbjct: 306 GISFVLGGLSLGMALPELKHFIEASVAATRILERINRVPQINDDDPKGLVLDQVRGEIEF 365
Query: 1183 KDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLID 1362
+ + F YPSR ++ VLK +L++ AG IALVGSSG GKST + L+QRFYD ++G V +D
Sbjct: 366 ESIRFVYPSRPNMTVLKDFNLQIPAGQTIALVGSSGSGKSTAIALVQRFYDASEGTVKVD 425
Query: 1363 GVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIK 1542
G+D++++N+ S+R +IG+VSQ+ LF +I ENI G AT D + A ANA++FI
Sbjct: 426 GIDIKKLNLKSIRSKIGLVSQDHALFGTSIKENILFGKPDATMDLLYAAAMTANAHNFIM 485
Query: 1543 RLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALD 1722
LP+GY T++GE+G LSGGQKQRIAIARA++KNP ILLLDEATSALD+E+E+ VQ ALD
Sbjct: 486 GLPEGYETKIGERGALLSGGQKQRIAIARAVLKNPAILLLDEATSALDSESEKLVQHALD 545
Query: 1723 QAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXX 1902
QA GRTT++VAH+LST++N D+I V G I E G+H+EL++K G + +
Sbjct: 546 QASMGRTTLVVAHKLSTVKNADQIAVVDGGRIAEIGTHDELINKGGPYSRLVKLQKMVSY 605
Query: 1903 XXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKAPPTSMF-KIFKF 2079
+ D S+ + ++E E +PP F ++
Sbjct: 606 IDQE----TDQFRASSAARTSASRLSMSRASPMPLTPGFSKETESYVSPPAPSFSRLLAM 661
Query: 2080 NGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSL-PADQMQANVYFWCGMFVLMGI 2256
N + S+ P +AL + + + ++M A + + +F + +
Sbjct: 662 NAPEWKQALIGSISALVYGSLQPTYALTIGGMIAAFFVQDHNEMNAIISRYALIFCSLSL 721
Query: 2257 TFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPN 2436
GE L ++R + + +L + A++D+ + +G LC+R + ++
Sbjct: 722 VSIAVNLLQHYNFAYMGEHLVRRIRVQVLEKILTFEAAWFDEDTNSSGSLCSRLSDESSL 781
Query: 2437 VR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQI 2613
V+ V R+ ++L + I A+ +G W+ M Y+ ++
Sbjct: 782 VKTLVADRISLLLQTACGIVIAVTMGLIVAWK-LALVMIAVQPCTMICYYAKKIVLSNVS 840
Query: 2614 RDTQLLE-EAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFA 2790
RD + E+ ++A +AV + R V S + + EP K + G
Sbjct: 841 RDLAKAQYESTQIAIEAVYNHRMVTSFGCSSKILQLFEHTQEEPLRKARKKSWVAGITTG 900
Query: 2791 FSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARL 2970
S L F +A F+ G + DV++ FF + G++I + S D+ K
Sbjct: 901 LSPCLTFLSWALDFWYGGKLAQSGEISAGDVFKTFFVLVSTGKLIADAGSMTSDLAKGAN 960
Query: 2971 AASLLFYLIEHP--TPIDSLSDSGIVK-PITGNISIRNVFFNYPTRKDTKVLQGFTLDIK 3141
A + +F +++ +P +S + K I G I + V F+YPTR +LQ F+LD+K
Sbjct: 961 AVASVFEVLDRKSISPQNSQVEKDNPKSKIQGRIEFKKVDFSYPTRPQCLILQDFSLDVK 1020
Query: 3142 AGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPT 3321
AG ++ LVG SGCGKSTI+GL++RFY+ D+G + IDG ++R +N+ R +VSQEP
Sbjct: 1021 AGTSIGLVGRSGCGKSTIIGLIQRFYDVDRGAVRIDGVDVREMNVLWYRGFTALVSQEPA 1080
Query: 3322 LFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQ 3501
+F ++ +NI +G +EIVEAAK AN H FI L DGYDT GE G QLSGGQKQ
Sbjct: 1081 MFSGSVRDNIAFG-KPEADEEEIVEAAKAANAHEFISSLKDGYDTDCGEHGIQLSGGQKQ 1139
Query: 3502 RIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDV 3681
RIAIARA++R+P++LLLDEATSALD +SE++VQEALD GRT +++AHRL+TI+N+D
Sbjct: 1140 RIAIARAIIRNPAILLLDEATSALDAQSEQVVQEALDRIMTGRTTIIVAHRLNTIKNADS 1199
Query: 3682 IAIVSEGKIVEKGTHDELIRKSEIYQKFCETQR 3780
IA + EGK++E+GT+ +L+ K + Q+
Sbjct: 1200 IAFLGEGKVIERGTYPQLMNKKGAFFNLATLQK 1232
Score = 310 bits (795), Expect = 1e-82
Identities = 182/521 (34%), Positives = 280/521 (52%), Gaps = 2/521 (0%)
Frame = +1
Query: 2230 CGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLC 2409
C FV + V C R E +++R + +LRQ++AF+D T ++
Sbjct: 85 CLNFVYLAFAILVVASMEGYCWSRTSERQVLRIRHLYLEAILRQEVAFFDSQEATTSEII 144
Query: 2410 TRFATDAPNVRYVFT-RLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFE 2586
+ DA ++ V + ++P+ L L Y+ W+ + G
Sbjct: 145 NSISKDASLIQEVLSEKVPLFLMHSTVFVSGLAFSTYFSWRLALVSYPLVLLLIIPGLIY 204
Query: 2587 MQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHA 2766
+ + +A + QA+ I+TV+S ++ Y L + N +K
Sbjct: 205 GKYLLYLSRESRREYAKANSLVEQALGSIKTVYSFTAEKGIIQRYTAILDKTINLGIKQG 264
Query: 2767 HTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFI 2946
G F+ L F ++A + GS V +Y + G +G +
Sbjct: 265 IAKGLAVGFT-GLSFAIWAFLAWYGSRLVMYHHESGGRIYAAGISFVLGGLSLGMALPEL 323
Query: 2947 PDVVKARLAASLLFYLIEHPTPIDSLSDSGIV-KPITGNISIRNVFFNYPTRKDTKVLQG 3123
++A +AA+ + I I+ G+V + G I ++ F YP+R + VL+
Sbjct: 324 KHFIEASVAATRILERINRVPQINDDDPKGLVLDQVRGEIEFESIRFVYPSRPNMTVLKD 383
Query: 3124 FTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCI 3303
F L I AG+T+ALVG SG GKST + L++RFY+ +G + +DG +I+ LN+ S+R ++ +
Sbjct: 384 FNLQIPAGQTIALVGSSGSGKSTAIALVQRFYDASEGTVKVDGIDIKKLNLKSIRSKIGL 443
Query: 3304 VSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQL 3483
VSQ+ LF +I ENI +G + T + AA AN HNFI+GLP+GY+T +GE+G L
Sbjct: 444 VSQDHALFGTSIKENILFG-KPDATMDLLYAAAMTANAHNFIMGLPEGYETKIGERGALL 502
Query: 3484 SGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLST 3663
SGGQKQRIAIARA++++P++LLLDEATSALD+ESEK+VQ ALD A GRT LV+AH+LST
Sbjct: 503 SGGQKQRIAIARAVLKNPAILLLDEATSALDSESEKLVQHALDQASMGRTTLVVAHKLST 562
Query: 3664 IQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRIV 3786
++N+D IA+V G+I E GTHDELI K Y + + Q++V
Sbjct: 563 VKNADQIAVVDGGRIAEIGTHDELINKGGPYSRLVKLQKMV 603
>gi|27368839|emb|CAD59577.1| MDR-like ABC transporter [Oryza sativa
(japonica cultivar-group)]
Length = 1234
Score = 698 bits (1802), Expect = 0.0
Identities = 425/1234 (34%), Positives = 669/1234 (53%), Gaps = 10/1234 (0%)
Frame = +1
Query: 109 GIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPE 288
G+F + VD+LL+ GT+ A+ G LL I + NS +G
Sbjct: 18 GMFKFADRVDVLLMALGTLGAIGDGCSTNLLLIFASDV-------MNS---LGYARAGAH 67
Query: 289 GLVPISLD-EFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAIL 465
G + +F EV K C+ ++ L + ++++ C+ +ER V ++R YL+AIL
Sbjct: 68 GGAAAATGVDFMREVEKSCLNFVYLAFAVLAVAFMEGYCWSRTSERQVLRIRYLYLQAIL 127
Query: 466 RQQIQWFDKQQ--TGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSM 639
RQ++ +FD Q+ T + ++ D ++E L +K L + F++G ++SW +
Sbjct: 128 RQEVGFFDSQEATTSEIINSISKDASLIQEVLSEKVPLFLMHSTVFISGLAFSTYFSWRL 187
Query: 640 TLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKREL 819
LV L+++ G K + +R + Y A ++ E+ SI+TV+S KR +
Sbjct: 188 ALVSFPLVLLLIIPGLIYGKYLLYLSRQSRHEYTNANSLVEQALGSIKTVYSFTAEKRII 247
Query: 820 DRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFT 999
R+ L+ + GI + G+ VGF+ L ++ +A WYGS L++ G I+
Sbjct: 248 QRYTAVLDKTIKLGIRQGIAKGLAVGFTGLS-FAIWAFLAWYGSRLVMYHHE-SGGRIYA 305
Query: 1000 VFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDIS 1179
+ + G SLG ALP L F A AA+ +L IN P+I+ +G+++D ++G++
Sbjct: 306 AGISFVLGGLSLGMALPELKHFTEASVAATRILDRINRVPEINADDPKGLILDQVRGELQ 365
Query: 1180 FKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLI 1359
F+ V F YPSR ++ VLK +L++ AG +ALVGSSG GKST + L+QRFYD T+G V +
Sbjct: 366 FESVRFVYPSRPNMTVLKDFNLQIPAGQTVALVGSSGSGKSTAIALVQRFYDATEGTVKV 425
Query: 1360 DGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFI 1539
DGV+++E+ + +R ++G+VSQ+ LF +I ENI G AT D++ A ANA++FI
Sbjct: 426 DGVNIKELQLKWIRSKMGLVSQDHALFGTSIKENILFGKPDATMDELYAAAMTANAHNFI 485
Query: 1540 KRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGAL 1719
+ LP+ Y T++GE+G LSGGQKQRIAIARA++KNP ILLLDEATSALD+E+E+ VQ AL
Sbjct: 486 RGLPEEYETKIGERGALLSGGQKQRIAIARAVIKNPAILLLDEATSALDSESEKLVQHAL 545
Query: 1720 DQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXX 1899
DQA GRTT++VAH+LST++N D+I V G I E G+H+EL++K G + +
Sbjct: 546 DQASMGRTTLVVAHKLSTVKNADQIAVVDGGTIAEIGTHDELINKGGPYSRLVKLQKMVS 605
Query: 1900 XXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKAPPTSMF-KIFK 2076
+ G D S+ + +++E + +PP F ++
Sbjct: 606 YIDQEG---GDQFRASSVARTSTSRLSMSRASPMPLTPGISKETDSSVSPPAPSFSRLLA 662
Query: 2077 FNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSL-PADQMQANVYFWCGMFVLMG 2253
N + S+ P++A+ + + + +M A + + +F +
Sbjct: 663 MNAPEWRQAVIGSLSALVYGSLQPIYAITIGGMIAAFFVQDLKEMNAIISRYALIFCSLS 722
Query: 2254 ITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAP 2433
+ V GE L ++R + + +L + A++D+ + +G LC+R + +A
Sbjct: 723 VISIVVNLLQHYNFAYMGEHLVRRIRVQVLEKILTFEAAWFDEETNSSGSLCSRLSNEAS 782
Query: 2434 NVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQ 2610
V+ V R+ ++L + I A+ +G W+ M Y+ ++
Sbjct: 783 LVKTLVADRISLLLQTASGIIIAVTMGLIVAWK-LALVMIAVQPTTMICYYAKKIVLSNV 841
Query: 2611 IRD-TQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVF 2787
RD + ++ ++A +AV + R V S + + EP K + G
Sbjct: 842 SRDLAKAQHQSTQIAIEAVYNHRMVTSFGCSSKVLQLFEHTQEEPLKRARKKSWVAGITT 901
Query: 2788 AFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKAR 2967
S L F +A F+ G + DV++ FF + G++I + S D+ K
Sbjct: 902 GLSPCLSFLSWALDFWYGGKLAQSGEISAGDVFKTFFVLVSTGKLIADAGSMTSDLAKGA 961
Query: 2968 LAASLLFYLIEHP--TPIDSLSDSGIVK-PITGNISIRNVFFNYPTRKDTKVLQGFTLDI 3138
A + +F +++ +P +S + K I G I + V F YPTR +LQ F+LD+
Sbjct: 962 NAVASVFEVLDRKSISPQNSQVEKDNQKNKIQGRIEFKRVDFAYPTRPQCLILQDFSLDV 1021
Query: 3139 KAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEP 3318
KAG ++ LVG SGCGKSTI+GL++RFY+ D+G + +DG ++R ++I R +VSQEP
Sbjct: 1022 KAGTSIGLVGRSGCGKSTIIGLIQRFYDVDRGAVKVDGMDVREMDILWYRGFTALVSQEP 1081
Query: 3319 TLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQK 3498
+F ++ +NI +G EIVEAAK AN H FI L DGY T GE G QLSGGQK
Sbjct: 1082 AIFSGSVRDNIAFG-KPEADEDEIVEAAKAANAHEFISSLKDGYHTDCGEHGLQLSGGQK 1140
Query: 3499 QRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSD 3678
QRIAIARA++R+P++LLLDEATSALD +SE++VQEALD GRT +V+AHRL+TI+N D
Sbjct: 1141 QRIAIARAIIRNPAILLLDEATSALDAQSEQVVQEALDRIMSGRTTIVVAHRLNTIKNVD 1200
Query: 3679 VIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQR 3780
IA + EGK+VE+GT+ L+ K + Q+
Sbjct: 1201 SIAFLGEGKVVERGTYPHLMSKKGAFYNLAALQK 1234
Score = 302 bits (774), Expect = 4e-80
Identities = 181/523 (34%), Positives = 279/523 (52%), Gaps = 4/523 (0%)
Frame = +1
Query: 2230 CGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLC 2409
C FV + F C R E +++R+ + +LRQ++ F+D T ++
Sbjct: 86 CLNFVYLAFAVLAVAFMEGYCWSRTSERQVLRIRYLYLQAILRQEVGFFDSQEATTSEII 145
Query: 2410 TRFATDAPNVRYVFT-RLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGG--Y 2580
+ DA ++ V + ++P+ L L Y+ W+ + G Y
Sbjct: 146 NSISKDASLIQEVLSEKVPLFLMHSTVFISGLAFSTYFSWRLALVSFPLVLLLIIPGLIY 205
Query: 2581 FEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLK 2760
+ + +Q R A + QA+ I+TV+S +++ Y L + ++
Sbjct: 206 GKYLLYLSRQSRHEYT--NANSLVEQALGSIKTVYSFTAEKRIIQRYTAVLDKTIKLGIR 263
Query: 2761 HAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTS 2940
G F+ L F ++A + GS V +Y + G +G
Sbjct: 264 QGIAKGLAVGFT-GLSFAIWAFLAWYGSRLVMYHHESGGRIYAAGISFVLGGLSLGMALP 322
Query: 2941 FIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIV-KPITGNISIRNVFFNYPTRKDTKVL 3117
+ +A +AA+ + I I++ G++ + G + +V F YP+R + VL
Sbjct: 323 ELKHFTEASVAATRILDRINRVPEINADDPKGLILDQVRGELQFESVRFVYPSRPNMTVL 382
Query: 3118 QGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQV 3297
+ F L I AG+TVALVG SG GKST + L++RFY+ +G + +DG NI+ L + +R ++
Sbjct: 383 KDFNLQIPAGQTVALVGSSGSGKSTAIALVQRFYDATEGTVKVDGVNIKELQLKWIRSKM 442
Query: 3298 CIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGT 3477
+VSQ+ LF +I ENI +G + T E+ AA AN HNFI GLP+ Y+T +GE+G
Sbjct: 443 GLVSQDHALFGTSIKENILFG-KPDATMDELYAAAMTANAHNFIRGLPEEYETKIGERGA 501
Query: 3478 QLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRL 3657
LSGGQKQRIAIARA++++P++LLLDEATSALD+ESEK+VQ ALD A GRT LV+AH+L
Sbjct: 502 LLSGGQKQRIAIARAVIKNPAILLLDEATSALDSESEKLVQHALDQASMGRTTLVVAHKL 561
Query: 3658 STIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRIV 3786
ST++N+D IA+V G I E GTHDELI K Y + + Q++V
Sbjct: 562 STVKNADQIAVVDGGTIAEIGTHDELINKGGPYSRLVKLQKMV 604
>gi|4574224|gb|AAD23956.1| multidrug resistance transporter homolog
[Fundulus heteroclitus]
Length = 851
Score = 692 bits (1785), Expect = 0.0
Identities = 382/846 (45%), Positives = 523/846 (61%), Gaps = 20/846 (2%)
Frame = +1
Query: 1300 STIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNE 1479
ST + LL+RFYDP +G V IDG D+R +NV LR IG+VSQEP+LF TI ENI+ G
Sbjct: 1 STTIQLLERFYDPQEGSVSIDGHDIRSLNVRYLRGMIGVVSQEPILFATTIAENIRYGRP 60
Query: 1480 HATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILL 1659
T +++ +A K ANA DFI LPD + T VG++G Q+SGGQKQRIAIARALV+ PKILL
Sbjct: 61 DVTEEEIEKAAKEANAYDFIMNLPDKFETLVGDRGTQMSGGQKQRIAIARALVRKPKILL 120
Query: 1660 LDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHE 1839
LDEATSALD E+E VQ ALD+ + GRTT+IVAH LSTIRN D I + G +VE G+H
Sbjct: 121 LDEATSALDAESETIVQAALDKVRQGRTTLIVAHCLSTIRNADVIAGLEKGKVVELGTHS 180
Query: 1840 ELMSKQGIFYDMTXXXXXXXXXXEAGKD---------IEDTISESAHSHLXXXXXXXXXX 1992
ELM K+G+++ + +D I + + ES
Sbjct: 181 ELMEKKGVYHTLVTMQTFQKADEGEDEDNLSAGEKSPIHNNVIESPLLRRKSTRGSSFAA 240
Query: 1993 XXXXXIHQLAEEVEECKA------PPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVF 2154
+ E+ +E K P S+FK+ + N + + ++ P+F
Sbjct: 241 SIGEKGDKKQEKEDEDKTEEDEDFPMVSIFKVLRLNASEWPYILVGLICATINGAIQPLF 300
Query: 2155 ALVYAEIFNVYSLPADQ--MQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKL 2328
A+++++I V++ P DQ ++ F+ MFV++G+ F F C G+ GE LT+KL
Sbjct: 301 AVLFSKIITVFAEP-DQTIIRQRANFFSLMFVVIGVVCFFTMFLQGFCFGKSGEVLTLKL 359
Query: 2329 RFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVF-TRLPVVLASIVTICGALG 2505
R AFK++LRQD+ ++D ++ G L TR ATDA V+ RL +I + +
Sbjct: 360 RLGAFKSMLRQDLGWFDSPKNSVGALTTRLATDAAQVQGASGVRLATFAQNIANLGTGVI 419
Query: 2506 IGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVH 2685
+ F YGW+ + G +M+M G D + LE+AGK+A++A+E+IRTV
Sbjct: 420 LAFVYGWELTLLILAVVPVIALAGAVQMKMLTGHAAEDKKELEKAGKIATEAIENIRTVA 479
Query: 2686 SLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQA 2865
SL R+ +F Y E L P+ + K AH YG F+FSQ++I+F YAA F G+ + +
Sbjct: 480 SLTREPKFESLYEENLVVPYKNSQKKAHVYGFTFSFSQAMIYFAYAACFRFGAWLIVEGR 539
Query: 2866 MQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVK 3045
M V+ V A+ F +G SF P+ KA+++AS L L+ ID+LS+ G
Sbjct: 540 MDVEAVFLVISAVLFGAMAVGEANSFAPNYAKAKMSASHLMMLLNKEPEIDNLSERGESP 599
Query: 3046 PI-TGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYN 3222
+ GN+S +V FNYP+R D +L+G L +K G+T+ALVG SGCGKST + LLERFY+
Sbjct: 600 DMFDGNVSFEDVKFNYPSRPDVPILRGLNLRVKKGETLALVGSSGCGKSTTIQLLERFYD 659
Query: 3223 QDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEA 3399
G +++D +++ LNI LR Q+ IVSQEP LFDC + ENI YG N R+VT +EI A
Sbjct: 660 PRDGRVVMDSIDVKRLNIHWLRSQIGIVSQEPVLFDCALAENIAYGDNSRSVTMEEIEAA 719
Query: 3400 AKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDT 3579
AK ANIHNFI LP Y+T G+KGTQLSGGQKQRIAIARA++R+P VLLLDEATSALDT
Sbjct: 720 AKAANIHNFINELPQKYNTQAGDKGTQLSGGQKQRIAIARAILRNPKVLLLDEATSALDT 779
Query: 3580 ESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQ 3759
ESEK+VQ+ALD A +GRTC+V+AHRLSTI+N+D IA+ G +VE+GTH +L+ K +Y
Sbjct: 780 ESEKVVQDALDQASKGRTCIVVAHRLSTIRNADRIAVFQGGVVVEQGTHQQLLAKKGVYH 839
Query: 3760 KFCETQ 3777
TQ
Sbjct: 840 MLVTTQ 845
Score = 433 bits (1114), Expect = e-119
Identities = 242/578 (41%), Positives = 346/578 (58%), Gaps = 4/578 (0%)
Frame = +1
Query: 148 LITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSE 327
++ G + A I+GA PL A++ + TVF P+ + F
Sbjct: 283 ILVGLICATINGAIQPLFAVLFSKIITVF--------------AEPDQTIIRQRANF--- 325
Query: 328 VVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD--KQQT 501
+ + ++V+GV+ FFT ++Q CF E L KLR K++LRQ + WFD K
Sbjct: 326 ---FSLMFVVIGVVCFFTMFLQGFCFGKSGEVLTLKLRLGAFKSMLRQDLGWFDSPKNSV 382
Query: 502 GNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLS 681
G LT RL D +V+ G + A Q A G + F Y W +TL+++ P+I L+
Sbjct: 383 GALTTRLATDAAQVQGASGVRLATFAQNIANLGTGVILAFVYGWELTLLILAVVPVIALA 442
Query: 682 GAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTG 861
GA K + +++ AG IA E +IRTV SL + + L V +
Sbjct: 443 GAVQMKMLTGHAAEDKKELEKAGKIATEAIENIRTVASLTREPKFESLYEENLVVPYKNS 502
Query: 862 IVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGG 1041
K G FS +Y +YA F +G+ LI+ + D +F V AVL G+ ++G
Sbjct: 503 QKKAHVYGFTFSFSQAMIYFAYAACFRFGAWLIV-EGRMDVEAVFLVISAVLFGAMAVGE 561
Query: 1042 ALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDI 1221
A ++ A+ +AS ++ ++N P+ID S G D G++SF+DV F YPSR D+
Sbjct: 562 ANSFAPNYAKAKMSASHLMMLLNKEPEIDNLSERGESPDMFDGNVSFEDVKFNYPSRPDV 621
Query: 1222 HVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLR 1401
+L+G++L +K G+ +ALVGSSGCGKST + LL+RFYDP GRV++D +D++ +N+H LR
Sbjct: 622 PILRGLNLRVKKGETLALVGSSGCGKSTTIQLLERFYDPRDGRVVMDSIDVKRLNIHWLR 681
Query: 1402 EQIGIVSQEPVLFDGTIYENIKMG--NEHATHDQVVEACKMANANDFIKRLPDGYGTRVG 1575
QIGIVSQEPVLFD + ENI G + T +++ A K AN ++FI LP Y T+ G
Sbjct: 682 SQIGIVSQEPVLFDCALAENIAYGDNSRSVTMEEIEAAAKAANIHNFINELPQKYNTQAG 741
Query: 1576 EKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIV 1755
+KG QLSGGQKQRIAIARA+++NPK+LLLDEATSALDTE+E+ VQ ALDQA GRT I+V
Sbjct: 742 DKGTQLSGGQKQRIAIARAILRNPKVLLLDEATSALDTESEKVVQDALDQASKGRTCIVV 801
Query: 1756 AHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFY 1869
AHRLSTIRN DRI VF+ G +VE G+H++L++K+G+++
Sbjct: 802 AHRLSTIRNADRIAVFQGGVVVEQGTHQQLLAKKGVYH 839
>gi|7494131|pir||T30804 P-glycoprotein 6 - Entamoeba histolytica
gi|405076|gb|AAA21449.1| P-glycoprotein 6
Length = 1282
Score = 685 bits (1767), Expect = 0.0
Identities = 424/1268 (33%), Positives = 668/1268 (52%), Gaps = 46/1268 (3%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F Y ++++ I G + ++ G +PL+AI++G D + +
Sbjct: 45 MFKYATWIEIIFNIIGVLISLCDGVLYPLIAILIG------------------DVFDSKA 86
Query: 292 LVPISLD--EFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAIL 465
P++ D E + K ++ +G+ +FFTS ++ F+ + ++R+ Y+K++L
Sbjct: 87 FNPLAYDVAEIENLCNKTSSKFMYIGIGLFFTSLIRTIIFDITGGNQIRRIRRLYIKSLL 146
Query: 466 RQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTL 645
Q++ W+D +G +T R++ D+ + + +G K F + GY +GF W +
Sbjct: 147 DQEMGWYDAHNSGEMTFRMSGDIFLLHDAIGQKVGEFFSYFGMCITGYVIGFVKEWKLCF 206
Query: 646 VMMGFAPLIVLSGAKMSKSMATRTRVE-QETYAVAGAIAEETFSSIRTVHSLNGHKRELD 822
VM+ AP +V A + + TRT Q +Y+VAG IA ET S++RTV +L K +
Sbjct: 207 VMISVAPFMV-GAAGIFAYVQTRTASSTQASYSVAGGIASETISNMRTVAALGIEKSRIR 265
Query: 823 RFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTV 1002
++ L GI G G ++ ++ + + YG+ I + V
Sbjct: 266 QYLQTLRHSLHVGIRASHETGGSTGLLFFFVFCAFWIGYIYGAKKI-QKRDMSASKLAIV 324
Query: 1003 FFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISF 1182
F+VL G+ L + S +A + + I PKI I + +G+I F
Sbjct: 325 VFSVLCGTLGLSQIATPIGSIFKGTSSAYRIFKTIERTPKIKNEGKRHIS-EIKEGNIVF 383
Query: 1183 KDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLID 1362
+ V F YP+R D+ +L +LE+KAG + LVG+SGCGKSTI+ LLQR Y+P G+++ID
Sbjct: 384 EGVSFCYPTRPDMLILNNFNLEIKAGHSVGLVGASGCGKSTIIGLLQRLYEPVDGKIMID 443
Query: 1363 GVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMG--------NEHATHD-------- 1494
G+D+RE +++ R G+V QEP LF +I ENI +G + H T D
Sbjct: 444 GIDIREFDLYEYRSMFGVVGQEPSLFAISIKENIALGAHRSILAPHYHDTSDPQDCLLMP 503
Query: 1495 ----QVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLL 1662
++++ +ANA +FI LP + T +G++G Q+SGGQKQRI+IARAL+ +PK+L+L
Sbjct: 504 ELEEKIMKCAHIANATNFINSLPQKFDTVLGQRGAQISGGQKQRISIARALMNDPKLLIL 563
Query: 1663 DEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEE 1842
DEATSALD ++E+ VQ ALD+A AGRT++I+AHRLSTIR+ RI VF G +VE G++
Sbjct: 564 DEATSALDFKSEKIVQRALDKAAAGRTSVIIAHRLSTIRDAHRILVFDHGQVVEDGNYTT 623
Query: 1843 LMSKQGIFYDMTXXXXXXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLA 2022
LM KQG+FY + E + ED + Q
Sbjct: 624 LMEKQGLFYKLVKNQEMGKKQQEKFDNDEDLEEDVVPDQTEVDKTYIEVDDDHRTNWQ-- 681
Query: 2023 EEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAE----IFNVY- 2187
+ A ++F+ N ++ W ++ P+FA AE + VY
Sbjct: 682 ----KFSAHFLVFGRVFRLNLKEIPWMILGFIGSMIYGALFPIFAYFLAEAICMLVTVYL 737
Query: 2188 SLPADQMQANVYFWCGMFVLMGIT--FFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQ 2361
+ +D + YF ++ +GI+ F+ + GE LT ++R +F + RQ
Sbjct: 738 TGMSDDSEIMKYF----YIFLGISGAMFISTYLHKAFFMMSGEFLTYRVRKLSFYAICRQ 793
Query: 2362 DIAFYDDLRHGTGKLCTRFATDAPNVRYVFTRL--PVVLASIVTICGALGIGFYYGWQXX 2535
DI ++D + TG+L R A DA + V L ++ S I G L +G+ +
Sbjct: 794 DIGWFDKKENSTGRLAGRLAADATKLNGVTGNLIGTMIHCSFSLIIG-LVLGYITNVKIS 852
Query: 2536 XXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHF 2715
Y ++++ G +T++ A + ++ VE+I+T+ L +++ F
Sbjct: 853 WVSTIFVPLIVFNTYIQLRISVGFAGPETKIYANAENLMTEVVENIKTIKMLAKEDYFKE 912
Query: 2716 TYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVF 2895
YC YL +P A G V + + IF+ Y+ Y+ + + D+ +
Sbjct: 913 KYCSYLVKPAKRAPFTAIINGLVLGWVHAFIFWKYSVLMYVAGQELKKDPSGMPDIMKAL 972
Query: 2896 FAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRN 3075
+I F +G +++ D A++AA +F +I+ +P D S+ G + + N
Sbjct: 973 CSIIFGAMSVGFAATYMADFGNAKVAAESIFKIIDRKSPQDPFSEEGEKNFTIDQVELDN 1032
Query: 3076 VFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGD 3255
+ F YPTR + +L G + I GK+VALVG SGCGKST++ L+ERFY +KG + I+G
Sbjct: 1033 IKFRYPTRPEQVILDGASFVIPKGKSVALVGPSGCGKSTVIQLIERFYKPEKGTVKINGR 1092
Query: 3256 NIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVT--------------YQEIV 3393
NI+ N+++LR ++ V QEP LF TIGENI G + T +IV
Sbjct: 1093 NIQEFNLATLRNKIGYVGQEPLLFAGTIGENIVSGMCGSWTDDQLENGGNLVAENMDKIV 1152
Query: 3394 EAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSAL 3573
AAKMAN HNFI LP GY+T +GE+GT LSGGQKQRIAIARAL+ P +L+LDEATSAL
Sbjct: 1153 AAAKMANCHNFICQLPQGYNTIIGERGTSLSGGQKQRIAIARALITQPELLILDEATSAL 1212
Query: 3574 DTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEI 3753
D+ESE IVQ+A+D + T +VIAHRLST+++SD+I ++S GK+VE+GTHDEL+++ +
Sbjct: 1213 DSESEMIVQQAIDKIAKQVTSIVIAHRLSTVKDSDIIVVLSGGKVVEQGTHDELMKEEGV 1272
Query: 3754 YQKFCETQ 3777
Y + Q
Sbjct: 1273 YFHLVQIQ 1280
Score = 269 bits (688), Expect = 3e-70
Identities = 189/582 (32%), Positives = 294/582 (50%), Gaps = 32/582 (5%)
Frame = +1
Query: 2146 PVFALVYAEIFNVYSL-PADQMQANVYFWCGM----FVLMGITFFVGFFTSANCLGRCGE 2310
P+ A++ ++F+ + P A + C F+ +GI F G
Sbjct: 72 PLIAILIGDVFDSKAFNPLAYDVAEIENLCNKTSSKFMYIGIGLFFTSLIRTIIFDITGG 131
Query: 2311 SLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVFTRLPVVLASIVTI 2490
+ ++R K+LL Q++ +YD H +G++ R + D + + S +
Sbjct: 132 NQIRRIRRLYIKSLLDQEMGWYD--AHNSGEMTFRMSGDIFLLHDAIGQKVGEFFSYFGM 189
Query: 2491 C-GALGIGFYYGWQXXXXXXXXX--XXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQA 2661
C IGF W+ G + +Q R + + + AG +AS+
Sbjct: 190 CITGYVIGFVKEWKLCFVMISVAPFMVGAAGIFAYVQTRTASSTQASYSV--AGGIASET 247
Query: 2662 VEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLG 2841
+ ++RTV +L ++ Y + LR + ++ +H G S L+FF AF++G
Sbjct: 248 ISNMRTVAALGIEKSRIRQYLQTLRHSLHVGIRASHETGG----STGLLFFFVFCAFWIG 303
Query: 2842 SIF----VNQQAMQPIDVYRVFFAISFCGQM-IGNTTSFIPDVVKARLAASLLFYLIEHP 3006
I+ + ++ M + V F++ CG + + + I + K +A +F IE
Sbjct: 304 YIYGAKKIQKRDMSASKLAIVVFSV-LCGTLGLSQIATPIGSIFKGTSSAYRIFKTIERT 362
Query: 3007 TPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGK 3186
I + I + GNI V F YPTR D +L F L+IKAG +V LVG SGCGK
Sbjct: 363 PKIKNEGKRHISEIKEGNIVFEGVSFCYPTRPDMLILNNFNLEIKAGHSVGLVGASGCGK 422
Query: 3187 STIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTN 3366
STI+GLL+R Y G IMIDG +IR ++ R +V QEP+LF +I ENI G +
Sbjct: 423 STIIGLLQRLYEPVDGKIMIDGIDIREFDLYEYRSMFGVVGQEPSLFAISIKENIALGAH 482
Query: 3367 RNVTY-------------------QEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSG 3489
R++ ++I++ A +AN NFI LP +DT +G++G Q+SG
Sbjct: 483 RSILAPHYHDTSDPQDCLLMPELEEKIMKCAHIANATNFINSLPQKFDTVLGQRGAQISG 542
Query: 3490 GQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQ 3669
GQKQRI+IARAL+ P +L+LDEATSALD +SEKIVQ ALD A GRT ++IAHRLSTI+
Sbjct: 543 GQKQRISIARALMNDPKLLILDEATSALDFKSEKIVQRALDKAAAGRTSVIIAHRLSTIR 602
Query: 3670 NSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRIVESQ 3795
++ I + G++VE G + L+ K ++ K + Q + + Q
Sbjct: 603 DAHRILVFDHGQVVEDGNYTTLMEKQGLFYKLVKNQEMGKKQ 644
>gi|34910738|ref|NP_916716.1| putative P-glycoprotein [Oryza sativa
(japonica cultivar-group)]
gi|20160550|dbj|BAB89499.1| putative P-glycoprotein [Oryza sativa
(japonica cultivar-group)]
Length = 1203
Score = 682 bits (1761), Expect = 0.0
Identities = 423/1233 (34%), Positives = 665/1233 (53%), Gaps = 9/1233 (0%)
Frame = +1
Query: 109 GIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPE 288
G+F + VD+LL+ GT+ A+ G LL I + NS +G
Sbjct: 18 GMFKFADRVDVLLMALGTLGAIGDGCSTNLLLIFASDV-------MNS---LGYARAGAH 67
Query: 289 GLVPISLD-EFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAIL 465
G + +F EV K C+ ++ L + ++++ C+ +ER V ++R YL+AIL
Sbjct: 68 GGAAAATGVDFMREVEKSCLNFVYLAFAVLAVAFMEGYCWSRTSERQVLRIRYLYLQAIL 127
Query: 466 RQQIQWFDKQQ--TGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSM 639
RQ++ +FD Q+ T + ++ D ++E L +K L + F++G ++SW +
Sbjct: 128 RQEVGFFDSQEATTSEIINSISKDASLIQEVLSEKVPLFLMHSTVFISGLAFSTYFSWRL 187
Query: 640 TLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKREL 819
LV L+++ G K + +R + Y A ++ E+ SI+TV+S KR +
Sbjct: 188 ALVSFPLVLLLIIPGLIYGKYLLYLSRQSRHEYTNANSLVEQALGSIKTVYSFTAEKRII 247
Query: 820 DRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFT 999
R+ L+ + GI + G+ VGF+ L ++ +A WYGS L++ G I+
Sbjct: 248 QRYTAVLDKTIKLGIRQGIAKGLAVGFTGLS-FAIWAFLAWYGSRLVMYHHE-SGGRIYA 305
Query: 1000 VFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDIS 1179
+ + G SLG ALP L F A AA+ +L IN P+I+ +G+++D ++G++
Sbjct: 306 AGISFVLGGLSLGMALPELKHFTEASVAATRILDRINRVPEINADDPKGLILDQVRGELQ 365
Query: 1180 FKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLI 1359
F+ V F YPSR ++ VLK +L++ AG +ALVGSSG GKST + L+QRFYD T+G V +
Sbjct: 366 FESVRFVYPSRPNMTVLKDFNLQIPAGQTVALVGSSGSGKSTAIALVQRFYDATEGTVKV 425
Query: 1360 DGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFI 1539
DGV+++E+ + +R ++G+VSQ+ LF +I ENI G AT D++ A ANA++FI
Sbjct: 426 DGVNIKELQLKWIRSKMGLVSQDHALFGTSIKENILFGKPDATMDELYAAAMTANAHNFI 485
Query: 1540 KRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGAL 1719
+ LP+ Y T++GE+G LSGGQKQRIAIARA++KNP ILLLDEATSALD+E+E+ VQ AL
Sbjct: 486 RGLPEEYETKIGERGALLSGGQKQRIAIARAVIKNPAILLLDEATSALDSESEKLVQHAL 545
Query: 1720 DQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXX 1899
DQA GRTT++VAH+LST++N D+I V G I E G+H+EL++K G + +
Sbjct: 546 DQASMGRTTLVVAHKLSTVKNADQIAVVDGGTIAEIGTHDELINKGGPYSRLVKLQKMGL 605
Query: 1900 XXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKAPPTSMFKIFKF 2079
+GKD +Q ++ V+ + ++
Sbjct: 606 F---SGKD----------------------------QYQPSQYVQ--SKSNATYTRLLAM 632
Query: 2080 NGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSL-PADQMQANVYFWCGMFVLMGI 2256
N + S+ P++A+ + + + +M A + + +F + +
Sbjct: 633 NAPEWRQAVIGSLSALVYGSLQPIYAITIGGMIAAFFVQDLKEMNAIISRYALIFCSLSV 692
Query: 2257 TFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPN 2436
V GE L ++R + + +L + A++D+ + +G LC+R + +A
Sbjct: 693 ISIVVNLLQHYNFAYMGEHLVRRIRVQVLEKILTFEAAWFDEETNSSGSLCSRLSNEASL 752
Query: 2437 VR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQI 2613
V+ V R+ ++L + I A+ +G W+ M Y+ ++
Sbjct: 753 VKTLVADRISLLLQTASGIIIAVTMGLIVAWK-LALVMIAVQPTTMICYYAKKIVLSNVS 811
Query: 2614 RD-TQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFA 2790
RD + ++ ++A +AV + R V S + + EP K + G
Sbjct: 812 RDLAKAQHQSTQIAIEAVYNHRMVTSFGCSSKVLQLFEHTQEEPLKRARKKSWVAGITTG 871
Query: 2791 FSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARL 2970
S L F +A F+ G + DV++ FF + G++I + S D+ K
Sbjct: 872 LSPCLSFLSWALDFWYGGKLAQSGEISAGDVFKTFFVLVSTGKLIADAGSMTSDLAKGAN 931
Query: 2971 AASLLFYLIEHP--TPIDSLSDSGIVK-PITGNISIRNVFFNYPTRKDTKVLQGFTLDIK 3141
A + +F +++ +P +S + K I G I + V F YPTR +LQ F+LD+K
Sbjct: 932 AVASVFEVLDRKSISPQNSQVEKDNQKNKIQGRIEFKRVDFAYPTRPQCLILQDFSLDVK 991
Query: 3142 AGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPT 3321
AG ++ LVG SGCGKSTI+GL++RFY+ D+G + +DG ++R ++I R +VSQEP
Sbjct: 992 AGTSIGLVGRSGCGKSTIIGLIQRFYDVDRGAVKVDGMDVREMDILWYRGFTALVSQEPA 1051
Query: 3322 LFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQ 3501
+F ++ +NI +G EIVEAAK AN H FI L DGY T GE G QLSGGQKQ
Sbjct: 1052 IFSGSVRDNIAFG-KPEADEDEIVEAAKAANAHEFISSLKDGYHTDCGEHGLQLSGGQKQ 1110
Query: 3502 RIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDV 3681
RIAIARA++R+P++LLLDEATSALD +SE++VQEALD GRT +V+AHRL+TI+N D
Sbjct: 1111 RIAIARAIIRNPAILLLDEATSALDAQSEQVVQEALDRIMSGRTTIVVAHRLNTIKNVDS 1170
Query: 3682 IAIVSEGKIVEKGTHDELIRKSEIYQKFCETQR 3780
IA + EGK+VE+GT+ L+ K + Q+
Sbjct: 1171 IAFLGEGKVVERGTYPHLMSKKGAFYNLAALQK 1203
Score = 301 bits (770), Expect = 1e-79
Identities = 180/522 (34%), Positives = 278/522 (52%), Gaps = 4/522 (0%)
Frame = +1
Query: 2230 CGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLC 2409
C FV + F C R E +++R+ + +LRQ++ F+D T ++
Sbjct: 86 CLNFVYLAFAVLAVAFMEGYCWSRTSERQVLRIRYLYLQAILRQEVGFFDSQEATTSEII 145
Query: 2410 TRFATDAPNVRYVFT-RLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGG--Y 2580
+ DA ++ V + ++P+ L L Y+ W+ + G Y
Sbjct: 146 NSISKDASLIQEVLSEKVPLFLMHSTVFISGLAFSTYFSWRLALVSFPLVLLLIIPGLIY 205
Query: 2581 FEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLK 2760
+ + +Q R A + QA+ I+TV+S +++ Y L + ++
Sbjct: 206 GKYLLYLSRQSRHEYT--NANSLVEQALGSIKTVYSFTAEKRIIQRYTAVLDKTIKLGIR 263
Query: 2761 HAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTS 2940
G F+ L F ++A + GS V +Y + G +G
Sbjct: 264 QGIAKGLAVGFT-GLSFAIWAFLAWYGSRLVMYHHESGGRIYAAGISFVLGGLSLGMALP 322
Query: 2941 FIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIV-KPITGNISIRNVFFNYPTRKDTKVL 3117
+ +A +AA+ + I I++ G++ + G + +V F YP+R + VL
Sbjct: 323 ELKHFTEASVAATRILDRINRVPEINADDPKGLILDQVRGELQFESVRFVYPSRPNMTVL 382
Query: 3118 QGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQV 3297
+ F L I AG+TVALVG SG GKST + L++RFY+ +G + +DG NI+ L + +R ++
Sbjct: 383 KDFNLQIPAGQTVALVGSSGSGKSTAIALVQRFYDATEGTVKVDGVNIKELQLKWIRSKM 442
Query: 3298 CIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGT 3477
+VSQ+ LF +I ENI +G + T E+ AA AN HNFI GLP+ Y+T +GE+G
Sbjct: 443 GLVSQDHALFGTSIKENILFG-KPDATMDELYAAAMTANAHNFIRGLPEEYETKIGERGA 501
Query: 3478 QLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRL 3657
LSGGQKQRIAIARA++++P++LLLDEATSALD+ESEK+VQ ALD A GRT LV+AH+L
Sbjct: 502 LLSGGQKQRIAIARAVIKNPAILLLDEATSALDSESEKLVQHALDQASMGRTTLVVAHKL 561
Query: 3658 STIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRI 3783
ST++N+D IA+V G I E GTHDELI K Y + + Q++
Sbjct: 562 STVKNADQIAVVDGGTIAEIGTHDELINKGGPYSRLVKLQKM 603
>gi|24960750|gb|AAN65444.1| Hypothetical protein [Oryza sativa
(japonica cultivar-group)]
Length = 1482
Score = 678 bits (1750), Expect = 0.0
Identities = 441/1278 (34%), Positives = 652/1278 (50%), Gaps = 68/1278 (5%)
Frame = +1
Query: 109 GIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPE 288
G+F Y+ +D++LL+ G V A+I+G P + + G +FV + NV+
Sbjct: 214 GLFKYSTAMDIVLLVLGCVGAMINGGSLPWYSYLFG------------NFVNKIVNVDKT 261
Query: 289 GLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILR 468
++ +V + +Y L ++ +Y++I C+ ER ++R+ YLKA+LR
Sbjct: 262 QMM--------KDVKQISVYMAFLAAVVVVGAYLEITCWRIIGERSALRMRREYLKAVLR 313
Query: 469 QQIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTL 645
Q+I +FD + TG + ++ D+ +++E +G+K V F+ GY VGF SW + L
Sbjct: 314 QEIGFFDTEVSTGEVMHSISGDVAQIQEVMGEKIPGFVHHVFTFVFGYVVGFAKSWRIAL 373
Query: 646 VMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDR 825
+ P ++ G T E+ +Y AG +A++ SSIRTV S +R
Sbjct: 374 AVFAVTPAMMACGMAYKAIYGGLTAKEEASYQRAGDVAQQAISSIRTVMSFVMEERLAGE 433
Query: 826 FYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVF 1005
+ L+ G+ G G+G L YS +ALA WYGS L+ N G F
Sbjct: 434 YAEWLDKAAPIGVKMGFAKGAGMGVIYLVTYSQWALALWYGSRLVANGE-IKGGDAIACF 492
Query: 1006 FAVLSGST------------------------SLGGALPHLASFGTARGAASTVLRVINS 1113
F V+ G L L ++A F AA V VI+
Sbjct: 493 FGVMVGGRHAHQPPRTASCCRQWRRSPEFRGWGLALTLSYMAQFAQGTVAAGRVFEVIDR 552
Query: 1114 HPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGC 1293
P+ID Y G + +KG + FKDV F YPSR D VL ++L + A +ALVG SG
Sbjct: 553 VPEIDAYGAGGRALPAVKGRMEFKDVEFAYPSRPDAMVLYNLNLVIPAAKTLALVGVSGG 612
Query: 1294 GKSTIVNLLQRFYDPTKGR--------------------------------VLIDGVDLR 1377
GKST+ L++RFYDPT+G + +DG DL
Sbjct: 613 GKSTMFALIERFYDPTRGEREWPLTRTQSTTMARSSVIDDEAFASVGCAGSITLDGHDLA 672
Query: 1378 EVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDG 1557
+N+ LR QIG+V QEPVLF +I EN+ MG E+AT + AC MAN + F+ LPDG
Sbjct: 673 SLNLRWLRSQIGLVGQEPVLFSTSIIENVMMGKENATRHDAISACAMANVHTFVLALPDG 732
Query: 1558 YGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAG 1737
Y T+VG++G QLSGGQKQRIA+ARA++++P+ILLLDE TSALDT++E VQ ++D+ AG
Sbjct: 733 YDTQVGDRGAQLSGGQKQRIALARAIIRDPRILLLDEPTSALDTQSEAVVQQSIDRLAAG 792
Query: 1738 RTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXXEAG 1917
RT +++AHRL+T+RN D I V G +VESG H +LM+++G + + A
Sbjct: 793 RTVVVIAHRLATVRNADTIAVLDRGAVVESGRHADLMARRGPYSALVSLASDSGG---AR 849
Query: 1918 KDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKAPPTSMFK---IFKFNGD 2088
D+ + +A++ Q E EE K + + I++
Sbjct: 850 PDLAG--AAAAYTSFTDESGYDVSVSKSRYGFQTIREEEEKKDSQDAKVRVSEIWRLQRR 907
Query: 2089 KVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPAD--QMQANVYFWCGMFVLMGITF 2262
+ +V VF L+ + VY AD +M+ V + V +G+
Sbjct: 908 EGPLLILGFLMGIHAGAVFSVFPLLLGQAVEVY-FDADTARMKRQVEYLAMAVVGLGVAC 966
Query: 2263 FVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVR 2442
+ G G LTM++R F+ ++RQ+ A++D+ + G L TR A DA R
Sbjct: 967 ILTMTGQQGLCGWAGARLTMRVRDRLFRAIMRQEPAWFDEEDNAMGVLVTRLARDAVAFR 1026
Query: 2443 YVF-TRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRD 2619
+F R V+L ++ + LGI F W+ Y + + G + D
Sbjct: 1027 SMFGDRYAVLLMAVGSAGVGLGICFGLDWRLTLVATACTPLTLGASYLNLLINVGARSDD 1086
Query: 2620 TQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQ 2799
+G +A+ AV ++RTV +L Q T+ L P + + G + SQ
Sbjct: 1087 GAYARASG-IAAGAVSNVRTVAALCAQGSVVGTFNRALDGPAAKASRRSQLMGVILGLSQ 1145
Query: 2800 SLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLA-A 2976
++ Y A G+ F+N DV ++F + +G PD A A A
Sbjct: 1146 GAMYGAYTATLCAGAHFINNGVSTFGDVSKIFLILVLSSFSVGQLAGLAPDTSGAPAAIA 1205
Query: 2977 SLLFYLIEHPTPIDSLSDSGIV----KPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKA 3144
+L L P + I KPI ++ +R V F YP+R + VL GF+L +KA
Sbjct: 1206 GILTILKRRPAITGDSTKRRITIKDGKPI--DVELRKVTFAYPSRPEVTVLSGFSLRVKA 1263
Query: 3145 GKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTL 3324
G TVA+VG SG GKST++ L++RFY+ G +++ G + R L++ LR + +V QEP L
Sbjct: 1264 GTTVAVVGASGSGKSTVVWLVQRFYDPGDGKVVVGGVDARELDLKWLRGECAMVGQEPAL 1323
Query: 3325 FDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQR 3504
F +I +NI +G N ++ EI EAAK ANIH FI LP GY+T VGE G QLSGGQKQR
Sbjct: 1324 FSGSIRDNIGFG-NPKASWAEIEEAAKEANIHKFISALPQGYETQVGESGVQLSGGQKQR 1382
Query: 3505 IAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVI 3684
IAIARA+V+ +LLLDEA+SALD ESE+ VQEAL A + T + +AHRLST++++D I
Sbjct: 1383 IAIARAIVKQARILLLDEASSALDLESERHVQEALRRASRRATAITVAHRLSTVRDADRI 1442
Query: 3685 AIVSEGKIVEKGTHDELI 3738
A+VS G++VE G HD L+
Sbjct: 1443 AVVSAGRVVEFGGHDALL 1460
Score = 327 bits (838), Expect = 1e-87
Identities = 214/577 (37%), Positives = 299/577 (51%), Gaps = 5/577 (0%)
Frame = +1
Query: 145 LLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNS 324
LLI G + + GA F + ++LG V+ A +
Sbjct: 911 LLILGFLMGIHAGAVFSVFPLLLGQAVEVYFDADTA--------------------RMKR 950
Query: 325 EVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQT- 501
+V + + LGV T Q RL ++R +AI+RQ+ WFD++
Sbjct: 951 QVEYLAMAVVGLGVACILTMTGQQGLCGWAGARLTMRVRDRLFRAIMRQEPAWFDEEDNA 1010
Query: 502 -GNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVL 678
G L RL D R GD++A+L+ + G G+ F W +TLV PL L
Sbjct: 1011 MGVLVTRLARDAVAFRSMFGDRYAVLLMAVGSAGVGLGICFGLDWRLTLVATACTPL-TL 1069
Query: 679 SGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQT 858
+ ++ + R + YA A IA S++RTV +L + F AL+
Sbjct: 1070 GASYLNLLINVGARSDDGAYARASGIAAGAVSNVRTVAALCAQGSVVGTFNRALDGPAAK 1129
Query: 859 GIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIIND-PTFDRGLIFTVFFAVLSGSTSL 1035
+ MG+ +G S MY +Y G+ I N TF G + +F ++ S S+
Sbjct: 1130 ASRRSQLMGVILGLSQGAMYGAYTATLCAGAHFINNGVSTF--GDVSKIFLILVLSSFSV 1187
Query: 1036 GGALPHLASFGTARGAASTVLRVINSHPKI--DPYSLEGILVDNMKGDISFKDVHFRYPS 1209
G A A + +L ++ P I D + D D+ + V F YPS
Sbjct: 1188 GQLAGLAPDTSGAPAAIAGILTILKRRPAITGDSTKRRITIKDGKPIDVELRKVTFAYPS 1247
Query: 1210 RKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNV 1389
R ++ VL G SL +KAG +A+VG+SG GKST+V L+QRFYDP G+V++ GVD RE+++
Sbjct: 1248 RPEVTVLSGFSLRVKAGTTVAVVGASGSGKSTVVWLVQRFYDPGDGKVVVGGVDARELDL 1307
Query: 1390 HSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTR 1569
LR + +V QEP LF G+I +NI GN A+ ++ EA K AN + FI LP GY T+
Sbjct: 1308 KWLRGECAMVGQEPALFSGSIRDNIGFGNPKASWAEIEEAAKEANIHKFISALPQGYETQ 1367
Query: 1570 VGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTI 1749
VGE GVQLSGGQKQRIAIARA+VK +ILLLDEA+SALD E+ER VQ AL +A T I
Sbjct: 1368 VGESGVQLSGGQKQRIAIARAIVKQARILLLDEASSALDLESERHVQEALRRASRRATAI 1427
Query: 1750 IVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQG 1860
VAHRLST+R+ DRI V AG +VE G H+ L++ G
Sbjct: 1428 TVAHRLSTVRDADRIAVVSAGRVVEFGGHDALLAGHG 1464
Score = 290 bits (743), Expect = 1e-76
Identities = 188/596 (31%), Positives = 286/596 (47%), Gaps = 59/596 (9%)
Frame = +1
Query: 2146 PVFALVYAEIFN-VYSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTM 2322
P ++ ++ N + ++ QM +V + VG + C GE +
Sbjct: 242 PWYSYLFGNFVNKIVNVDKTQMMKDVKQISVYMAFLAAVVVVGAYLEITCWRIIGERSAL 301
Query: 2323 KLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVF-TRLPVVLASIVTICGA 2499
++R E K +LRQ+I F+D TG++ + D ++ V ++P + + T
Sbjct: 302 RMRREYLKAVLRQEIGFFDT-EVSTGEVMHSISGDVAQIQEVMGEKIPGFVHHVFTFVFG 360
Query: 2500 LGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRT 2679
+GF W+ G + G ++ + AG VA QA+ IRT
Sbjct: 361 YVVGFAKSWRIALAVFAVTPAMMACGMAYKAIYGGLTAKEEASYQRAGDVAQQAISSIRT 420
Query: 2680 VHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQ 2859
V S +E+ Y E+L + +K GA + + +A A + GS V
Sbjct: 421 VMSFVMEERLAGEYAEWLDKAAPIGVKMGFAKGAGMGVIYLVTYSQWALALWYGSRLVAN 480
Query: 2860 QAMQPIDVYRVFFAI------------------------SFCGQMIGNTTSFIPDVVKAR 2967
++ D FF + F G + T S++ +
Sbjct: 481 GEIKGGDAIACFFGVMVGGRHAHQPPRTASCCRQWRRSPEFRGWGLALTLSYMAQFAQGT 540
Query: 2968 LAASLLFYLIEHPTPIDSLSDSGIVKP-ITGNISIRNVFFNYPTRKDTKVLQGFTLDIKA 3144
+AA +F +I+ ID+ G P + G + ++V F YP+R D VL L I A
Sbjct: 541 VAAGRVFEVIDRVPEIDAYGAGGRALPAVKGRMEFKDVEFAYPSRPDAMVLYNLNLVIPA 600
Query: 3145 GKTVALVGHSGCGKSTIMGLLERFYNQDKG------------------------------ 3234
KT+ALVG SG GKST+ L+ERFY+ +G
Sbjct: 601 AKTLALVGVSGGGKSTMFALIERFYDPTRGEREWPLTRTQSTTMARSSVIDDEAFASVGC 660
Query: 3235 --MIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKM 3408
I +DG ++ +LN+ LR Q+ +V QEP LF +I EN+ G N T + + A M
Sbjct: 661 AGSITLDGHDLASLNLRWLRSQIGLVGQEPVLFSTSIIENVMMG-KENATRHDAISACAM 719
Query: 3409 ANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESE 3588
AN+H F+L LPDGYDT VG++G QLSGGQKQRIA+ARA++R P +LLLDE TSALDT+SE
Sbjct: 720 ANVHTFVLALPDGYDTQVGDRGAQLSGGQKQRIALARAIIRDPRILLLDEPTSALDTQSE 779
Query: 3589 KIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIY 3756
+VQ+++D GRT +VIAHRL+T++N+D IA++ G +VE G H +L+ + Y
Sbjct: 780 AVVQQSIDRLAAGRTVVVIAHRLATVRNADTIAVLDRGAVVESGRHADLMARRGPY 835
>gi|25297460|pir||B86240 protein F20B24.12 [imported] - Arabidopsis
thaliana
gi|6573748|gb|AAF17668.1| F20B24.12 [Arabidopsis thaliana]
Length = 1316
Score = 677 bits (1748), Expect = 0.0
Identities = 434/1330 (32%), Positives = 692/1330 (51%), Gaps = 100/1330 (7%)
Frame = +1
Query: 91 VKLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGV 270
+KL ++ FY D +L+ G++ A IHGA P+ I G +
Sbjct: 27 LKLFSFADFY-----DCVLMALGSIGACIHGASVPVFFIFFGKL---------------- 65
Query: 271 DNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNY 450
+N GL + E + +V KY + ++ L V++ F+S++++AC+ ER K+R+ Y
Sbjct: 66 --INIIGLAYLFPQEASHKVAKYSLDFVYLSVVILFSSWLEVACWMHTGERQAAKIRKAY 123
Query: 451 LKAILRQQIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFAL------------------ 573
L+++L Q I FD + TG + + +T ++ V++ + +K
Sbjct: 124 LRSMLSQDISLFDTEISTGEVISAITSEILVVQDAISEKVRYTKIKPVLVLNFGCWIFNF 183
Query: 574 ----------LVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSG---AKMSKSMATR 714
+ + F+AG+ +GF W ++LV + P I L+G A +S + R
Sbjct: 184 PIASMHLVGNFMHFISRFIAGFAIGFASVWQISLVTLSIVPFIALAGGIYAFVSSGLIVR 243
Query: 715 TRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNAL----EVGRQTGIVKYCYM 882
R ++Y A IAEE ++RTV + G ++ + + AL GR+ G+ K
Sbjct: 244 VR---KSYVKANEIAEEVIGNVRTVQAFTGEEKAVSSYQGALRNTYNYGRKAGLAK---- 296
Query: 883 GIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGS---------TSL 1035
G+G+G + ++ S+AL W+ ++++++ + G FT V+ SL
Sbjct: 297 GLGLGSLHFVLFLSWALLIWF-TSIVVHKGIANGGESFTTMLNVVIAGFHNKALFLYRSL 355
Query: 1036 GGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRK 1215
G A P +++F A AA + ++I + + G + N+ GDI FKDV F YPSR
Sbjct: 356 GQAAPDISTFMRASAAAYPIFQMIERNTE----DKTGRKLGNVNGDILFKDVTFTYPSRP 411
Query: 1216 DIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHS 1395
D+ + ++ + AG +ALVG SG GKST+++L++RFY+PT G V++DG D+R +++
Sbjct: 412 DVVIFDKLNFVIPAGKVVALVGGSGSGKSTMISLIERFYEPTDGAVMLDGNDIRYLDLKW 471
Query: 1396 LREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDG------ 1557
LR IG+V+QEPVLF TI ENI G + AT +++ A K++ A FI LP+G
Sbjct: 472 LRGHIGLVNQEPVLFATTIRENIMYGKDDATSEEITNAAKLSEAISFINNLPEGFETQVC 531
Query: 1558 ---------------------YGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEAT 1674
+G +VGE+G+QLSGGQKQRI+I+RA+VKNP ILLLDEAT
Sbjct: 532 RTSDSLEHKKLTTVNPRFCLLFGLQVGERGIQLSGGQKQRISISRAIVKNPSILLLDEAT 591
Query: 1675 SALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSK 1854
SALD E+E+ VQ ALD+ GRTT++VAHRLST+RN D I V G I+ESGSH+EL+S
Sbjct: 592 SALDAESEKIVQEALDRVMVGRTTVVVAHRLSTVRNADIIAVVGGGKIIESGSHDELISN 651
Query: 1855 QGIFYDMTXXXXXXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVE 2034
Y A ++ T S + IHQ + +
Sbjct: 652 PDGAY-----SSLLRIQEAASPNLNHTPSLPVST---KPLPELPITETTSSIHQSVNQPD 703
Query: 2035 ECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQA 2214
K ++ +++ + S P+FAL A+ Y + + Q
Sbjct: 704 TTKQAKVTVGRLYSMIRPDWKYGLCGTLGSFIAGSQMPLFALGIAQALVSYYMDWETTQN 763
Query: 2215 NVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHG 2394
V +F + + G GE LT+++R + F +LR +I ++D + +
Sbjct: 764 EVKRISILFCCGSVITVIVHTIEHTTFGIMGERLTLRVRQKMFSAILRNEIGWFDKVDNT 823
Query: 2395 TGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXM 2571
+ L +R +DA +R V R ++L ++ + A I F W+
Sbjct: 824 SSMLASRLESDATLLRTIVVDRSTILLENLGLVVTAFIISFILNWRLTLVVLATYPLIIS 883
Query: 2572 GGYFEMQ--------MRFGKQI--------RDTQLLEEAGKVASQAVEHIRTVHSLNRQE 2703
G E++ + FG+Q ++ +A +A +++ +IRTV + +E
Sbjct: 884 GHISEVKRSFLRFYILFFGRQKIFMQGYGGNLSKAYLKANMLAGESISNIRTVVAFCAEE 943
Query: 2704 QFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFY---------LGSIFVN 2856
+ Y + L EP + + G ++ SQ IF Y A + GSI +
Sbjct: 944 KVLDLYSKELLEPSERSFRRGQMAGILYGVSQFFIFSSYGLALWYIYKLFHTKYGSILME 1003
Query: 2857 QQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSG 3036
+ V + F + ++G + PD++K +F L++ T + + D+G
Sbjct: 1004 KGLSSFESVMKTFMVLIVTALVMGEVLALAPDLLKGNQMVVSVFELLDRRTQV--VGDTG 1061
Query: 3037 -IVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLER 3213
+ + G I ++ V F+YP+R D + F L + +GK++ALVG SG GKS+++ L+ R
Sbjct: 1062 EELSNVEGTIELKGVHFSYPSRPDVTIFSDFNLLVPSGKSMALVGQSGSGKSSVLSLVLR 1121
Query: 3214 FYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIV 3393
FY+ G+IMIDG +I+ L + SLR + +V QEP LF TI ENI YG + E++
Sbjct: 1122 FYDPTAGIIMIDGQDIKKLKLKSLRRHIGLVQQEPALFATTIYENILYG-KEGASESEVM 1180
Query: 3394 EAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSAL 3573
EAAK+AN H+FI LP+GY T VGE+G Q+SGGQ+QRIAIARA++++P +LLLDEATSAL
Sbjct: 1181 EAAKLANAHSFISSLPEGYSTKVGERGIQMSGGQRQRIAIARAVLKNPEILLLDEATSAL 1240
Query: 3574 DTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELI-RKSE 3750
D ESE++VQ+ALD + RT +V+AHRLSTI+NSD+I+++ +GKI+E+G+H+ L+ K+
Sbjct: 1241 DVESERVVQQALDRLMRDRTTVVVAHRLSTIKNSDMISVIQDGKIIEQGSHNILVENKNG 1300
Query: 3751 IYQKFCETQR 3780
Y K Q+
Sbjct: 1301 PYSKLISLQQ 1310
Score = 285 bits (728), Expect = 8e-75
Identities = 205/647 (31%), Positives = 307/647 (46%), Gaps = 70/647 (10%)
Frame = +1
Query: 2008 IHQLAEEVEECKAPPTSMFKIFKFNG--DKVGWXXXXXXXXXXXXSVTPVFALVYAEIFN 2181
I +A +E K P S K+F F D V SV PVF + + ++ N
Sbjct: 9 IVDMAAAEKEKKRPSVSFLKLFSFADFYDCVLMALGSIGACIHGASV-PVFFIFFGKLIN 67
Query: 2182 VYSLP---ADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNL 2352
+ L + V + FV + + + C GE K+R +++
Sbjct: 68 IIGLAYLFPQEASHKVAKYSLDFVYLSVVILFSSWLEVACWMHTGERQAAKIRKAYLRSM 127
Query: 2353 LRQDIAFYDDLRHGTGKLCTRFAT------DAPNVRYVFTRLPVVLAS------------ 2478
L QDI+ +D TG++ + + DA + + +T++ VL
Sbjct: 128 LSQDISLFDT-EISTGEVISAITSEILVVQDAISEKVRYTKIKPVLVLNFGCWIFNFPIA 186
Query: 2479 -----------IVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQ 2625
I IGF WQ + G + G +R +
Sbjct: 187 SMHLVGNFMHFISRFIAGFAIGFASVWQISLVTLSIVPFIALAGGIYAFVSSGLIVRVRK 246
Query: 2626 LLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSL 2805
+A ++A + + ++RTV + +E+ +Y LR +N K G +
Sbjct: 247 SYVKANEIAEEVIGNVRTVQAFTGEEKAVSSYQGALRNTYNYGRKAGLAKGLGLGSLHFV 306
Query: 2806 IFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCG---------QMIGNTTSFIPDVV 2958
+F +A + SI V++ + + + G + +G I +
Sbjct: 307 LFLSWALLIWFTSIVVHKGIANGGESFTTMLNVVIAGFHNKALFLYRSLGQAAPDISTFM 366
Query: 2959 KARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDI 3138
+A AA +F +IE T + G V G+I ++V F YP+R D + I
Sbjct: 367 RASAAAYPIFQMIERNTEDKTGRKLGNVN---GDILFKDVTFTYPSRPDVVIFDKLNFVI 423
Query: 3139 KAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEP 3318
AGK VALVG SG GKST++ L+ERFY G +M+DG++IR L++ LR + +V+QEP
Sbjct: 424 PAGKVVALVGGSGSGKSTMISLIERFYEPTDGAVMLDGNDIRYLDLKWLRGHIGLVNQEP 483
Query: 3319 TLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHV------------ 3462
LF TI ENI YG + + T +EI AAK++ +FI LP+G++T V
Sbjct: 484 VLFATTIRENIMYGKD-DATSEEITNAAKLSEAISFINNLPEGFETQVCRTSDSLEHKKL 542
Query: 3463 ---------------GEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIV 3597
GE+G QLSGGQKQRI+I+RA+V++PS+LLLDEATSALD ESEKIV
Sbjct: 543 TTVNPRFCLLFGLQVGERGIQLSGGQKQRISISRAIVKNPSILLLDEATSALDAESEKIV 602
Query: 3598 QEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELI 3738
QEALD GRT +V+AHRLST++N+D+IA+V GKI+E G+HDELI
Sbjct: 603 QEALDRVMVGRTTVVVAHRLSTVRNADIIAVVGGGKIIESGSHDELI 649
>gi|38345252|emb|CAD41096.2| OSJNBb0011N17.13 [Oryza sativa (japonica
cultivar-group)]
Length = 1271
Score = 677 bits (1747), Expect = 0.0
Identities = 427/1249 (34%), Positives = 659/1249 (52%), Gaps = 43/1249 (3%)
Frame = +1
Query: 121 YTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVP 300
Y D L+ G + + G PL +VLG + V++ G
Sbjct: 15 YADAHDRCLMALGVLGSFGDGMMQPLSMLVLGDI---------------VNSYGGAGGAG 59
Query: 301 ISLDEFNSEVV-KYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQI 477
+ F+S V K+ + L + V + S+++ C+ AER K+R+ YL+A+L Q++
Sbjct: 60 SARSAFSSGAVDKFALRLLYVAVAVGACSFLEGLCWTRTAERQASKMRRLYLEAVLSQEV 119
Query: 478 QWFD-------------KQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVG 618
+FD + T + + ++DD + +++ LG+K +++ F V
Sbjct: 120 AFFDAAPSSPSSPQAQAQATTFRVISTVSDDADAIQDFLGEKLPMVLANATLFFGALAVS 179
Query: 619 FFYSWSMTLVMMGFAPLI-VLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHS 795
F ++W + L + F L+ V ++ MA + Y AG IA++ SSIRTV S
Sbjct: 180 FVFAWRLALAGLPFTLLLFVTPSVLLAGRMAAAAGEARAAYEEAGGIAQQAVSSIRTVAS 239
Query: 796 LNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPT 975
+R ++RF A+ G+ + G +G + +Y+ ++ W GS L+I+
Sbjct: 240 YTAERRTVERFRGAVARSAALGVRQGLIKGAVIGSMGV-IYAVWSFLSWIGSLLVIHLHA 298
Query: 976 FDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILV 1155
G +F ++ S+ ALP+L F A AAS + +I P ++ +G +
Sbjct: 299 -QGGHVFVASICIVLAGMSIMMALPNLRYFIDATAAASRMQEMIEMLPPLEGAEKKGATM 357
Query: 1156 DNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYD 1335
+ ++G+I FKDVHF YPSR D VL G +L + G + LVG SG GKST+++LLQRFY
Sbjct: 358 ERIRGEIVFKDVHFSYPSRPDTLVLNGFNLTISEGATVGLVGGSGSGKSTVISLLQRFYS 417
Query: 1336 PTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACK 1515
P G + +D + +NV LR QIG+VSQEPVLF +I ENI G+E A+ QVV A K
Sbjct: 418 PDSGEISMDDHGIDTLNVEWLRSQIGLVSQEPVLFATSIRENILFGDETASLKQVVAAAK 477
Query: 1516 MANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEA 1695
MANA++FI +LP GY T VG+ G QLSGGQKQRIAIARALV++P+ILLLDEATSALD E+
Sbjct: 478 MANAHEFIVKLPHGYETHVGQFGTQLSGGQKQRIAIARALVRDPRILLLDEATSALDAES 537
Query: 1696 EREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELM-----SKQG 1860
ER VQ ALD+A GRTT+IVAHRLST+R D I V AG +VE+G+H+EL+ + G
Sbjct: 538 ERTVQDALDRASVGRTTVIVAHRLSTLRKADTIAVLDAGRVVEAGTHDELLGMDDGGEGG 597
Query: 1861 IFYDMTXXXXXXXXXXE---------------AGKDIEDTISESAHSHLXXXXXXXXXXX 1995
++ M + + +E + SA H
Sbjct: 598 VYARMVHLQKAPPVAAREERHRAVDVVESEMVSFRSVEIMSAVSATEHRPSPAPSFCSVE 657
Query: 1996 XXXXIHQLAEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEI 2175
I + + ++ S ++ K N + +V P+++ +
Sbjct: 658 HSTEIGRKLVDHGVARSRKPSKLRLLKMNRPEWKQALLGCVGAVVFGAVLPLYSYSLGSL 717
Query: 2176 FNVYSLPAD-QMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNL 2352
VY L D Q+++ + +F+ + + GE LT ++R + +
Sbjct: 718 PEVYFLADDGQIRSKTRLYYFLFLGIAVVCITANIVQHYNFAVMGERLTERVRGQMLAKI 777
Query: 2353 LRQDIAFYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQ 2529
L ++ ++D+ + + +C R AT + VR V R+ +++ + T + W+
Sbjct: 778 LSFEVGWFDEDENSSAAVCARLATQSSKVRSLVGDRMCLLVQAGATASLGFSLALAVSWR 837
Query: 2530 XXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQF 2709
YF+ + + + + ++AS+AV + RT+ + + Q +
Sbjct: 838 LATVMMAMQPLIIASFYFKKVLMAAMSKKAKKAQVQGSQLASEAVVNHRTITAFSSQRRM 897
Query: 2710 HFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYR 2889
Y + P N+ H+ G Q A A + G + + + P +++
Sbjct: 898 LRLYEAAQQGPKKDNVAHSWFSGFCLCLCQFSNTGSMAVALWYGGKLMAKGLITPTHLFQ 957
Query: 2890 VFFAISFCGQMIGNTTSFIPDVVKARLAA-SLLFYLIEHPTPIDSLSDSGIV----KPIT 3054
VFF + G++I + S D+ + A S+L L PT D +D+ K I
Sbjct: 958 VFFMLMTMGRVIADAGSLTSDLAQGGDAVRSVLDTLDREPTIKDDDNDNERKKKKRKEIK 1017
Query: 3055 GNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKG 3234
G I +NV F+YPTR + VL GF+L+I AGKTVALVG SG GKST++GL+ERFY+ +G
Sbjct: 1018 GAIEFKNVHFSYPTRPEVAVLAGFSLEIGAGKTVALVGPSGSGKSTVIGLIERFYDAQRG 1077
Query: 3235 MIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYG-TNRNVTYQEIVEAAKMA 3411
+++DG++IR+ +++ LR QV +VSQEPTLF TI +NI YG + T E+ AA +A
Sbjct: 1078 SVLVDGEDIRSYSLARLRSQVALVSQEPTLFSGTIRDNIAYGAAEEHATEDEVARAAALA 1137
Query: 3412 NIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEK 3591
N H FI + GYDT VGE+G QLSGGQ+QRIA+ARA+++ +LLLDEATSALD SE+
Sbjct: 1138 NAHGFISAMERGYDTRVGERGAQLSGGQRQRIALARAVLKDARILLLDEATSALDAASER 1197
Query: 3592 IVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELI 3738
+VQ+A+D +GRTC+V+AHRLST++ SD IA+V +G++ E+G H EL+
Sbjct: 1198 LVQDAVDRMLRGRTCVVVAHRLSTVEKSDTIAVVKDGRVAERGRHHELL 1246
Score = 347 bits (890), Expect = 1e-93
Identities = 219/592 (36%), Positives = 316/592 (52%), Gaps = 17/592 (2%)
Frame = +1
Query: 151 ITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEV 330
+ G V AV+ GA PL + LG + V+ A + + S+
Sbjct: 694 LLGCVGAVVFGAVLPLYSYSLGSLPEVYFLADDG--------------------QIRSKT 733
Query: 331 VKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGN- 507
Y +L + V+ + VQ F ERL ++R L IL ++ WFD+ + +
Sbjct: 734 RLYYFLFLGIAVVCITANIVQHYNFAVMGERLTERVRGQMLAKILSFEVGWFDEDENSSA 793
Query: 508 -LTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSG 684
+ ARL +VR +GD+ LLVQ A G+ + SW + VMM PLI+ S
Sbjct: 794 AVCARLATQSSKVRSLVGDRMCLLVQAGATASLGFSLALAVSWRLATVMMAMQPLIIASF 853
Query: 685 AKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGI 864
MA ++ ++ +A E + RT+ + + +R L R Y A + G +
Sbjct: 854 YFKKVLMAAMSKKAKKAQVQGSQLASEAVVNHRTITAFSSQRRML-RLYEAAQQGPKKDN 912
Query: 865 VKYCYMGIGVGFSN-LCMYS---SYALAFWYGSTLIIND---PTFDRGLIFTVFFAVLSG 1023
V + + GF LC +S S A+A WYG L+ PT +F VFF +++
Sbjct: 913 VAHSWFS---GFCLCLCQFSNTGSMAVALWYGGKLMAKGLITPTH----LFQVFFMLMTM 965
Query: 1024 STSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDN----MKGDISFKDV 1191
+ A + A +VL ++ P I + +KG I FK+V
Sbjct: 966 GRVIADAGSLTSDLAQGGDAVRSVLDTLDREPTIKDDDNDNERKKKKRKEIKGAIEFKNV 1025
Query: 1192 HFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVD 1371
HF YP+R ++ VL G SLE+ AG +ALVG SG GKST++ L++RFYD +G VL+DG D
Sbjct: 1026 HFSYPTRPEVAVLAGFSLEIGAGKTVALVGPSGSGKSTVIGLIERFYDAQRGSVLVDGED 1085
Query: 1372 LREVNVHSLREQIGIVSQEPVLFDGTIYENIKMG--NEHATHDQVVEACKMANANDFIKR 1545
+R ++ LR Q+ +VSQEP LF GTI +NI G EHAT D+V A +ANA+ FI
Sbjct: 1086 IRSYSLARLRSQVALVSQEPTLFSGTIRDNIAYGAAEEHATEDEVARAAALANAHGFISA 1145
Query: 1546 LPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQ 1725
+ GY TRVGE+G QLSGGQ+QRIA+ARA++K+ +ILLLDEATSALD +ER VQ A+D+
Sbjct: 1146 MERGYDTRVGERGAQLSGGQRQRIALARAVLKDARILLLDEATSALDAASERLVQDAVDR 1205
Query: 1726 AQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMS--KQGIFYDM 1875
GRT ++VAHRLST+ D I V K G + E G H EL++ + G +Y++
Sbjct: 1206 MLRGRTCVVVAHRLSTVEKSDTIAVVKDGRVAERGRHHELLAVGRAGTYYNL 1257
>gi|27368841|emb|CAD59578.1| MDR-like ABC transporter [Oryza sativa
(japonica cultivar-group)]
gi|37806005|dbj|BAC99418.1| MDR-like ABC transporter [Oryza sativa
(japonica cultivar-group)]
gi|37806249|dbj|BAC99766.1| MDR-like ABC transporter [Oryza sativa
(japonica cultivar-group)]
Length = 1266
Score = 676 bits (1744), Expect = 0.0
Identities = 423/1238 (34%), Positives = 659/1238 (53%), Gaps = 20/1238 (1%)
Frame = +1
Query: 94 KLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVD 273
K +G+ Y G+D LL++ GT+ + +HG +G + +L + D VVG +
Sbjct: 40 KFPFFGLLRYADGLDWLLMVAGTMGSFLHG---------MGPSMSYYLVGKGID-VVGNN 89
Query: 274 NVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYL 453
N E V E+ K Y L ++ ++I C+ ++R + ++R YL
Sbjct: 90 IGNREATV--------HELSKLIPYMWALAIITLPGGMIEITCWMYTSQRQMSRMRMAYL 141
Query: 454 KAILRQQIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYS 630
+++L Q I FD T N+ A T+ + +++ +G+K + F+ FL V F
Sbjct: 142 RSVLSQDIGAFDTDLTTANVMAGATNHMSAIQDAIGEKLGHFLSNFSTFLVSIIVAFVCC 201
Query: 631 WSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHK 810
W + ++ M P++++ GA +K M + + A + E+T S I+TV S G
Sbjct: 202 WEVGMLSMLVVPMLLMVGATYAKMMIDASMKRIALVSAATTVVEQTLSHIKTVFSFVGEN 261
Query: 811 RELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGL 990
+ F ++ + ++ G+G+G + + SY+L W G+ ++ D + G
Sbjct: 262 SAIKSFTKCMDKQYKLSKIEAMTKGLGLGMLQIATFCSYSLTVWVGAAAVV-DRSAKGGE 320
Query: 991 IFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKG 1170
+LS + + A P L SF A+ A V VIN +P I Y G +++ + G
Sbjct: 321 TIAAVINILSAAIYISNAAPDLQSFSQAKAAGKEVFEVINRNPAIS-YESNGTILEKVTG 379
Query: 1171 DISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGR 1350
+I ++V F YPSR D +L+ SL + AG +ALVGSSGCGKST+++L+QRFYDP G
Sbjct: 380 NIEIREVDFMYPSRVDKPILRSFSLSIPAGKVVALVGSSGCGKSTVISLVQRFYDPISGN 439
Query: 1351 VLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAN 1530
+LIDG +++E+++ SLR IG VSQEP LF GTI +N+++G T ++++E K AN +
Sbjct: 440 ILIDGQNIKELDLKSLRRSIGSVSQEPSLFSGTIMDNLRIGKMDGTDEEIIEIAKSANVH 499
Query: 1531 DFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQ 1710
F+ +LP+ Y T VGE+GVQLSGGQKQRIAIARA++K+P ILLLDEATSALD+E+E+ VQ
Sbjct: 500 SFVSKLPNQYSTEVGERGVQLSGGQKQRIAIARAMLKDPPILLLDEATSALDSESEKLVQ 559
Query: 1711 GALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXX 1890
ALD A GRT I++AHR+STI N D+I V + G + +SG+HEEL+ K + +
Sbjct: 560 EALDGAMKGRTVILIAHRMSTIINSDKIVVVENGKVAQSGTHEELLEKSPFYSSVCSMQN 619
Query: 1891 XXXXXXEAGKDIEDTISE-----SAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKAPPT 2055
++ + D + E S S+ +Q +++ +
Sbjct: 620 LEKESGKSEERFTDQVREEQDNGSGTSNEPSSTAHEQEKSLELNPNQPKQDIRNRASAFY 679
Query: 2056 SMF-KIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANVYFWC 2232
MF F K+ P+FA + Y P D + +
Sbjct: 680 RMFLGTFMLEPGKI---LLGSTAAAISGVSKPIFAFYIMTVAIAYFDP-DAKRIVAKYSI 735
Query: 2233 GMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCT 2412
+F++ +TFF F G GE LR F +L+ +I +++ ++ G L +
Sbjct: 736 ILFLIGLLTFFSNIF-QHYIYGLVGERAMNNLREALFSVILQNEIGWFEQPKNSVGFLTS 794
Query: 2413 RFATDAPNVRYVFT-RLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEM 2589
R D ++ + + R+ V++ I +I A G+ W+ + G ++
Sbjct: 795 RVVGDTSMIKTIISDRMSVIVQCISSILIATGLSIGVNWRMGLVAWALMPCQFIAGLVQV 854
Query: 2590 QMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAH 2769
+ G + + + S+AV +IRTV S ++E+ L+EP T+ +
Sbjct: 855 RSAKGFATDTSTSHRKLISLTSEAVSNIRTVASFGQEEEILKKADLSLQEPMQTSRIESI 914
Query: 2770 TYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIP 2949
YG V S L +A A + +++ + R + AI+ I S IP
Sbjct: 915 KYGVVQGVSLCLWHMTHAIALSYTIVLLDKSLATFENCVRAYQAIALTITSITELWSLIP 974
Query: 2950 DVVKARLAASLLFYLIEHPTPIDSLSDSGIV---KPITGNISIRNVFFNYPTRKDTKVLQ 3120
V+ A +++ T I + D V ITGNI ++V F+YP+R+D +L
Sbjct: 975 MVISAIAILDPALDILDRETQI--VPDEPKVHCEDRITGNIEFQDVSFSYPSRQDVIILD 1032
Query: 3121 GFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVC 3300
GF+L I+ G+ VALVG SG GKSTI+ LL RFY+ +G +++DG ++R N+ LR+Q+
Sbjct: 1033 GFSLAIEPGQRVALVGPSGAGKSTIVSLLLRFYDPCRGQVLVDGKDVREYNLRFLRKQIG 1092
Query: 3301 IVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQ 3480
+V QEP LF+ +I ENI YG N + EIVEAA ANIH FI GL +GYDT VG+KG+Q
Sbjct: 1093 LVQQEPILFNLSIRENISYG-NEGASETEIVEAAMEANIHEFISGLSNGYDTVVGDKGSQ 1151
Query: 3481 LSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDA----AKQGR-----T 3633
LSGGQKQRIAIAR +++ P +LLLDEATSALD E+EK+V +L A +K+G T
Sbjct: 1152 LSGGQKQRIAIARTILKRPVILLLDEATSALDGETEKVVMSSLAAKEWKSKEGELSNKIT 1211
Query: 3634 CLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKS 3747
+ IAHRLST+ ++DVI ++ +G++VE G+H+ L+ S
Sbjct: 1212 SITIAHRLSTVTSADVIVVMDKGEVVEMGSHETLVTTS 1249
Score = 324 bits (830), Expect = 1e-86
Identities = 212/606 (34%), Positives = 323/606 (52%), Gaps = 18/606 (2%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNP 285
Y +F T ++ ++ G+ AA I G P+ A + V + +P
Sbjct: 679 YRMFLGTFMLEPGKILLGSTAAAISGVSKPIFAFYI--------------MTVAIAYFDP 724
Query: 286 EGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAIL 465
+ V KY I ++G+L FF++ Q + ER ++ LR+ IL
Sbjct: 725 DA---------KRIVAKYSIILFLIGLLTFFSNIFQHYIYGLVGERAMNNLREALFSVIL 775
Query: 466 RQQIQWFD--KQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSM 639
+ +I WF+ K G LT+R+ D ++ + D+ +++VQ ++ L G+ +W M
Sbjct: 776 QNEIGWFEQPKNSVGFLTSRVVGDTSMIKTIISDRMSVIVQCISSILIATGLSIGVNWRM 835
Query: 640 TLVMMGFAPLIVLSG---AKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHK 810
LV P ++G + +K AT T ++ E S+IRTV S +
Sbjct: 836 GLVAWALMPCQFIAGLVQVRSAKGFATDTSTSHRKLI---SLTSEAVSNIRTVASFGQEE 892
Query: 811 RELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDP---TFD 981
L + +L+ QT ++ G+ G S + ++A+A Y T+++ D TF+
Sbjct: 893 EILKKADLSLQEPMQTSRIESIKYGVVQGVSLCLWHMTHAIALSY--TIVLLDKSLATFE 950
Query: 982 RGL-IFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVD 1158
+ + ++ T L +P + S A L +++ +I P + D
Sbjct: 951 NCVRAYQAIALTITSITELWSLIPMVIS---AIAILDPALDILDRETQIVPDEPKVHCED 1007
Query: 1159 NMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDP 1338
+ G+I F+DV F YPSR+D+ +L G SL ++ G ++ALVG SG GKSTIV+LL RFYDP
Sbjct: 1008 RITGNIEFQDVSFSYPSRQDVIILDGFSLAIEPGQRVALVGPSGAGKSTIVSLLLRFYDP 1067
Query: 1339 TKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKM 1518
+G+VL+DG D+RE N+ LR+QIG+V QEP+LF+ +I ENI GNE A+ ++VEA
Sbjct: 1068 CRGQVLVDGKDVREYNLRFLRKQIGLVQQEPILFNLSIRENISYGNEGASETEIVEAAME 1127
Query: 1519 ANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAE 1698
AN ++FI L +GY T VG+KG QLSGGQKQRIAIAR ++K P ILLLDEATSALD E E
Sbjct: 1128 ANIHEFISGLSNGYDTVVGDKGSQLSGGQKQRIAIARTILKRPVILLLDEATSALDGETE 1187
Query: 1699 REVQGALD----QAQAGR-----TTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMS 1851
+ V +L +++ G T+I +AHRLST+ + D I V G +VE GSHE L++
Sbjct: 1188 KVVMSSLAAKEWKSKEGELSNKITSITIAHRLSTVTSADVIVVMDKGEVVEMGSHETLVT 1247
Query: 1852 KQGIFY 1869
Y
Sbjct: 1248 TSNGVY 1253
Score = 311 bits (798), Expect = 6e-83
Identities = 189/523 (36%), Positives = 280/523 (53%), Gaps = 2/523 (0%)
Frame = +1
Query: 2221 YFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYD-DLRHGT 2397
Y W + I G C + ++R +++L QDI +D DL T
Sbjct: 106 YMWA-----LAIITLPGGMIEITCWMYTSQRQMSRMRMAYLRSVLSQDIGAFDTDLT--T 158
Query: 2398 GKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMG 2574
+ ++ + +L L++ T ++ + F W+ M
Sbjct: 159 ANVMAGATNHMSAIQDAIGEKLGHFLSNFSTFLVSIIVAFVCCWEVGMLSMLVVPMLLMV 218
Query: 2575 GYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTN 2754
G +M ++ L+ A V Q + HI+TV S + ++ + + + + +
Sbjct: 219 GATYAKMMIDASMKRIALVSAATTVVEQTLSHIKTVFSFVGENSAIKSFTKCMDKQYKLS 278
Query: 2755 LKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNT 2934
A T G Q F Y+ ++G+ V ++ + + I I N
Sbjct: 279 KIEAMTKGLGLGMLQIATFCSYSLTVWVGAAAVVDRSAKGGETIAAVINILSAAIYISNA 338
Query: 2935 TSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKV 3114
+ +A+ A +F +I I S+ I++ +TGNI IR V F YP+R D +
Sbjct: 339 APDLQSFSQAKAAGKEVFEVINRNPAISYESNGTILEKVTGNIEIREVDFMYPSRVDKPI 398
Query: 3115 LQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQ 3294
L+ F+L I AGK VALVG SGCGKST++ L++RFY+ G I+IDG NI+ L++ SLR
Sbjct: 399 LRSFSLSIPAGKVVALVGSSGCGKSTVISLVQRFYDPISGNILIDGQNIKELDLKSLRRS 458
Query: 3295 VCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKG 3474
+ VSQEP+LF TI +N+ G + T +EI+E AK AN+H+F+ LP+ Y T VGE+G
Sbjct: 459 IGSVSQEPSLFSGTIMDNLRIG-KMDGTDEEIIEIAKSANVHSFVSKLPNQYSTEVGERG 517
Query: 3475 TQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHR 3654
QLSGGQKQRIAIARA+++ P +LLLDEATSALD+ESEK+VQEALD A +GRT ++IAHR
Sbjct: 518 VQLSGGQKQRIAIARAMLKDPPILLLDEATSALDSESEKLVQEALDGAMKGRTVILIAHR 577
Query: 3655 LSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRI 3783
+STI NSD I +V GK+ + GTH+EL+ KS Y C Q +
Sbjct: 578 MSTIINSDKIVVVENGKVAQSGTHEELLEKSPFYSSVCSMQNL 620
>gi|37695542|gb|AAR00316.1| PGP1; ZMPGP1 [Zea mays]
Length = 1394
Score = 672 bits (1735), Expect = 0.0
Identities = 423/1247 (33%), Positives = 664/1247 (52%), Gaps = 37/1247 (2%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
+F + G+D L++ GT+ A++HG P+ + F G +P+
Sbjct: 127 LFRFADGLDCALMLIGTLGALVHGCSLPVFLRFFADLVDSF----------GSHADDPDT 176
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
+V + VVKY Y+LV+G ++ +S+ +I+C+ ER ++R YL A LRQ
Sbjct: 177 MVRL--------VVKYAFYFLVVGAAIWASSWAEISCWMWTGERQSTRMRIRYLDAALRQ 228
Query: 472 QIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLV 648
+ +FD + ++ + D V++ + K L+ A F+AG+ VGF +W + LV
Sbjct: 229 DVSFFDTDVRASDVIYAINADAVVVQDAISQKLGNLIHYMATFVAGFVVGFTAAWQLALV 288
Query: 649 MMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRF 828
+ PLI + G + ++A + Q+ + A IAE+ + IR V + G +RE+ +
Sbjct: 289 TLAVVPLIAVIGGLSAAALAKLSSRSQDALSGASGIAEQALAQIRIVQAFVGEEREMRAY 348
Query: 829 YNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFF 1008
AL V ++ G G+G+G + ++ Y L WYG L+ T + GL F
Sbjct: 349 SAALAVAQRIGYRSGFAKGLGLGGTYFTVFCCYGLLLWYGGHLVRAQHT-NGGLAIATMF 407
Query: 1009 AVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKD 1188
+V+ G A P +A+F AR AA+ + R+I+ P I S +G +++ G + +
Sbjct: 408 SVMIGGLPRQSA-PSMAAFAKARVAAAKIFRIIDHRPGIS--SRDGAEPESVTGRVEMRG 464
Query: 1189 VHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGV 1368
V F YPSR D+ +L+G SL + AG IALVGSSG GKST+V+L++RFYDP+ G++L+DG
Sbjct: 465 VDFAYPSRPDVPILRGFSLSVPAGKTIALVGSSGSGKSTVVSLIERFYDPSAGQILLDGH 524
Query: 1369 DLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMG--NEHATHDQVVEACKMANANDFIK 1542
DLR + + LR QIG+VSQEP LF +I EN+ +G ++ AT ++ EA ++ANA+ FI
Sbjct: 525 DLRSLELRWLRRQIGLVSQEPALFATSIRENLLLGRDSQSATLAEMEEAARVANAHSFII 584
Query: 1543 RLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALD 1722
+LPDGY T+VGE+G+QLSGGQKQRIAIARA++KNP ILLLDEATSALD+E+E+ VQ ALD
Sbjct: 585 KLPDGYDTQVGERGLQLSGGQKQRIAIARAMLKNPAILLLDEATSALDSESEKLVQEALD 644
Query: 1723 QAQAGRTTI-IVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSK--------------Q 1857
+ GRTT+ A D + V + G + E +H+ELM+K Q
Sbjct: 645 RFMMGRTTLGDRATGCPPSAKADVVAVLQGGAVSEMSAHDELMAKGENGTYAKLIRMQEQ 704
Query: 1858 GIFYDMTXXXXXXXXXXEAGKDIEDTI----SESAHSHLXXXXXXXXXXXXXXXIHQ--- 2016
+ A + I S S IH
Sbjct: 705 AHEAALVNARRSSARPSSARNSVSSPIMTRNSSYGRSPYSRRLSDFSTSDFTLSIHDPHH 764
Query: 2017 ----LAEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNV 2184
+A++ +A +S ++ + N + + S + +FA + + + +V
Sbjct: 765 HHRTMADKQLAFRAGASSFLRLARMNSPEWAYALAGSIGSMVCGSFSAIFAYILSAVLSV 824
Query: 2185 YSLPADQ-MQANVYFWCGMFVLMGITFFVGFFTSANCL--GRCGESLTMKLRFEAFKNLL 2355
Y P + M+ + +C ++L+G++ F + + GE+LT ++R + F +
Sbjct: 825 YYAPDPRYMKREIAKYC--YLLIGMSSAALLFNTVQHVFWDTVGENLTKRVREKMFAAVF 882
Query: 2356 RQDIAFYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQX 2532
R +IA++D + + ++ R A DA NVR + R+ V++ + + A GF W+
Sbjct: 883 RNEIAWFDADENASARVTARLALDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWR- 941
Query: 2533 XXXXXXXXXXXXMGGYFEMQMRFGKQIR-DTQLLE-EAGKVASQAVEHIRTVHSLNRQEQ 2706
+ G +Q F K D + A ++A +AV ++RTV + N + +
Sbjct: 942 -LALVLLAVFPLVVGATVLQKMFMKGFSGDLEAAHARATQIAGEAVANLRTVAAFNAERK 1000
Query: 2707 FHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVY 2886
+ LR P G+ + +Q L++ YA + + V
Sbjct: 1001 ITGLFEANLRGPLRRCFWKGQIAGSGYGVAQFLLYASYALGLWYAAWLVKHGVSDFSRTI 1060
Query: 2887 RVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLS-DSGIVKPITG-N 3060
RVF + T + PD +K A +F I+ T ++ D+ V G
Sbjct: 1061 RVFMVLMVSANGAAETLTLAPDFIKGGRAMRSVFETIDRKTEVEPHDVDAAPVPDGPGAK 1120
Query: 3061 ISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMI 3240
+ +++V F YP+R D +V + +L +AGKT+ALVG SG GKS+++ L++RFY G +
Sbjct: 1121 VELKHVDFLYPSRPDIQVFRDLSLRARAGKTLALVGPSGSGKSSVLALVQRFYKPTSGRV 1180
Query: 3241 MIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIH 3420
++DG ++R N+ +LR V +V QEP LF +I ENI YG T E+VEAA AN H
Sbjct: 1181 LLDGKDVRKYNLRALRRVVAVVPQEPFLFAASIHENIAYG-REGATEAEVVEAAAQANAH 1239
Query: 3421 NFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQ 3600
FI LP+GY T VGE+G QLSGGQ+QRIAIARALV+ +++LLDEATSALD ESE+ VQ
Sbjct: 1240 RFIAALPEGYRTQVGERGVQLSGGQRQRIAIARALVKQAAIVLLDEATSALDAESERCVQ 1299
Query: 3601 EALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIR 3741
EAL+ A GRT +V+AHRL+T++ + IA++ +GK+ E+G+H L++
Sbjct: 1300 EALERAGSGRTTIVVAHRLATVRGAHTIAVIDDGKVAEQGSHSHLLK 1346
Score = 293 bits (751), Expect = 2e-77
Identities = 194/576 (33%), Positives = 293/576 (50%), Gaps = 8/576 (1%)
Frame = +1
Query: 2047 PPTSMFKIFKF-NGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQ---MQA 2214
PP ++ +F+F +G PVF +A++ + + AD M
Sbjct: 120 PPAALRDLFRFADGLDCALMLIGTLGALVHGCSLPVFLRFFADLVDSFGSHADDPDTMVR 179
Query: 2215 NVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYD-DLRH 2391
V + F+++G + + +C GE + ++R LRQD++F+D D+R
Sbjct: 180 LVVKYAFYFLVVGAAIWASSWAEISCWMWTGERQSTRMRIRYLDAALRQDVSFFDTDVR- 238
Query: 2392 GTGKLCTRFATDAPNVRYVFT-RLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXX 2568
+ DA V+ + +L ++ + T +GF WQ
Sbjct: 239 -ASDVIYAINADAVVVQDAISQKLGNLIHYMATFVAGFVVGFTAAWQLALVTLAVVPLIA 297
Query: 2569 MGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFN 2748
+ G R L A +A QA+ IR V + +E+ Y L
Sbjct: 298 VIGGLSAAALAKLSSRSQDALSGASGIAEQALAQIRIVQAFVGEEREMRAYSAALAVAQR 357
Query: 2749 TNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIG 2928
+ G + +F Y + G V Q F++ G +
Sbjct: 358 IGYRSGFAKGLGLGGTYFTVFCCYGLLLWYGGHLVRAQHTNGGLAIATMFSVMI-GGLPR 416
Query: 2929 NTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDT 3108
+ + KAR+AA+ +F +I+H I S D + +TG + +R V F YP+R D
Sbjct: 417 QSAPSMAAFAKARVAAAKIFRIIDHRPGISS-RDGAEPESVTGRVEMRGVDFAYPSRPDV 475
Query: 3109 KVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLR 3288
+L+GF+L + AGKT+ALVG SG GKST++ L+ERFY+ G I++DG ++R+L + LR
Sbjct: 476 PILRGFSLSVPAGKTIALVGSSGSGKSTVVSLIERFYDPSAGQILLDGHDLRSLELRWLR 535
Query: 3289 EQVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLPDGYDTHVG 3465
Q+ +VSQEP LF +I EN+ G + ++ T E+ EAA++AN H+FI+ LPDGYDT VG
Sbjct: 536 RQIGLVSQEPALFATSIRENLLLGRDSQSATLAEMEEAARVANAHSFIIKLPDGYDTQVG 595
Query: 3466 EKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCL-V 3642
E+G QLSGGQKQRIAIARA++++P++LLLDEATSALD+ESEK+VQEALD GRT L
Sbjct: 596 ERGLQLSGGQKQRIAIARAMLKNPAILLLDEATSALDSESEKLVQEALDRFMMGRTTLGD 655
Query: 3643 IAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSE 3750
A +DV+A++ G + E HDEL+ K E
Sbjct: 656 RATGCPPSAKADVVAVLQGGAVSEMSAHDELMAKGE 691
>gi|2360941|gb|AAB69130.1| P-glycoprotein
Length = 1341
Score = 669 bits (1727), Expect = 0.0
Identities = 430/1237 (34%), Positives = 650/1237 (51%), Gaps = 28/1237 (2%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
IF Y D +L+I GT+ AV GAG P + + G + T D + GV +V
Sbjct: 121 IFRYADTADRVLMIIGTIFAVCSGAGMPFFSFIFGRIAT--------DLMSGVGSVE--- 169
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
K + + +G+ MF + C+ A R ++R N+ +A+LRQ
Sbjct: 170 ----------LSAAKTSLIMVYVGIGMFVACGGHVLCWTVAASRQERRIRLNFFRAVLRQ 219
Query: 472 QIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVM 651
I W D++ G LTAR+T D ++ G+ DK + + A + GY GF +SW +TLVM
Sbjct: 220 DIGWHDERSPGELTARMTGDTRVIQNGINDKLSQGIMNGAMGIIGYIAGFVFSWELTLVM 279
Query: 652 MGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFY 831
+G P I++ A + ++ T ++ +A AG++A E +IRTV EL RF
Sbjct: 280 VGMMPFIIVMAAIIGNIVSKMTESSRKHFAKAGSLATEVMENIRTVQVFGREDYELQRFA 339
Query: 832 NALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFA 1011
A+ + GI K + +Y SY +AF++GS L+ D I + F A
Sbjct: 340 EAVLHAQDRGIRKEFAGSLSEAVIMALVYLSYTIAFFFGSYLV-EWGRRDMADIISTFLA 398
Query: 1012 VLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDV 1191
VL GS LG P A+F +R AA + + I+ P +D +G+ V K I F++V
Sbjct: 399 VLMGSFGLGFVAPSAAAFTESRAAAYEIFKAIDRVPPVD-IDADGVPVTGFKQSIEFRNV 457
Query: 1192 HFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVD 1371
F YP+R D+ + + ++L++K G K+A GSSGCGKS+++ L+QRFYDP G VL DGVD
Sbjct: 458 RFSYPTRPDMILFRDLNLKIKCGQKVAFSGSSGCGKSSMIGLIQRFYDPAGGAVLCDGVD 517
Query: 1372 LREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLP 1551
+RE+ +H R+QIGIVSQEP+LF GT+ EN+++G +AT ++V+EAC+ AN +D I LP
Sbjct: 518 MRELCLHDWRDQIGIVSQEPILFAGTMMENVRVGKPNATEEEVIEACRQANVHDTIMSLP 577
Query: 1552 DGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQ-- 1725
D Y T VG G QLSGGQKQRIAIARALVK P ILLLDEATSALD ++E EVQ +LDQ
Sbjct: 578 DQYNTPVGAVGSQLSGGQKQRIAIARALVKRPPILLLDEATSALDRKSEMEVQRSLDQLM 637
Query: 1726 AQAGRTTIIVAHRLSTIRNVDRIFVFK-----AGNIVESGSHEELMSKQGIFYDMTXXXX 1890
+ G T I++AHRL+TIRNVD I+ K I ESG+ +ELM G F M
Sbjct: 638 ERGGVTVIVIAHRLATIRNVDCIYCVKYDGAEGSKIAESGTFDELMELGGEFAAMARIQG 697
Query: 1891 XXXXXXEAGKDIED----------TISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEEC 2040
+G +D T+ E A +HL + +LA+ E
Sbjct: 698 VSTGDARSGARGQDGDRENDFLNMTLDEEALAHL--DEEAPRTARQKVPVEELAK--LEV 753
Query: 2041 KAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNV---YSL--PADQ 2205
++ + N DK + P +++ + V YS+ +Q
Sbjct: 754 NGVNVGFRRLMEMNKDKSWAVALGILGSAVGGAARPTSSILMGYMLRVLGEYSVNKNVEQ 813
Query: 2206 MQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDL 2385
+++ + +F+L + F+G + G GE LT K+R F+ ++RQD+ F+D
Sbjct: 814 LRSGTNLYAPLFILFAVANFLG-WALHGFYGYAGEHLTTKIRVLLFRQIMRQDMNFFDIP 872
Query: 2386 RHGTGKLCTRFATDAPNVRYVFTRLPVVLASIVTIC---GALGIGFYYGWQXXXXXXXXX 2556
G L + D V ++ P + + T+C + + F Y W+
Sbjct: 873 GRDAGTLAGMLSGDCEAVHQLWG--PSIGLKVQTVCIVASGVVVSFIYQWKLALVALACM 930
Query: 2557 XXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLR 2736
E M G ++ + + + ++A+ +RTV S N + + LR
Sbjct: 931 PLLIGCSLAERMMMNG--YTKSKEGDTSDTIVTEALSSVRTVTSFNMKADRVEAFEATLR 988
Query: 2737 EPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCG 2916
++K G+++ +Q + + YA F+ GS +++ Q +V +I F
Sbjct: 989 VEAPRSVKKGIIAGSIYGATQFIYYSAYALCFWYGSKLIDRGEAQFTNVMIASTSILFGA 1048
Query: 2917 QMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITG-NISIRNVFFNYP 3093
Q G +F + A +A +F +I+ +D + SG G ++ + V F Y
Sbjct: 1049 QNAGEAGAFATKLADAERSAKRVFSVIDRVPDVD-IEQSGDKDLGKGCDVDFQRVQFIYS 1107
Query: 3094 TRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLN 3273
R VL+ L G L+G +GCGKSTI+ +L RFY++ G+I ++G ++ +L+
Sbjct: 1108 ARPKQVVLESVNLRFGDGTVNGLMGQTGCGKSTIIQMLARFYDRRSGLICVNGKDLSSLD 1167
Query: 3274 ISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYD 3453
I+ R + +V QEP LF T+ ENI Y + T +E+ EAA++A+IH I+ PDGY+
Sbjct: 1168 IAEWRRNISVVLQEPNLFSGTVRENIRY-AREDATDEEVEEAARLAHIHWEIVKWPDGYN 1226
Query: 3454 THVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDA--AKQG 3627
T VG KG+ LSGGQKQR+AIAR L+R P +LLLDEATSALD +E VQE ++A AK
Sbjct: 1227 TEVGYKGSALSGGQKQRVAIARGLLRRPKLLLLDEATSALDNVTEAKVQEGINAYQAKYE 1286
Query: 3628 RTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELI 3738
T + IAHRL+TI++ D I ++ G I+E+G+H+EL+
Sbjct: 1287 VTSVSIAHRLTTIRHCDQIILLDSGHIIEQGSHEELM 1323
Score = 298 bits (763), Expect = 7e-79
Identities = 203/583 (34%), Positives = 301/583 (50%), Gaps = 10/583 (1%)
Frame = +1
Query: 157 GTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEVVK 336
G + + + GA P +I++G M V +G +VN ++++ S
Sbjct: 777 GILGSAVGGAARPTSSILMGYMLRV----------LGEYSVNK------NVEQLRSGTNL 820
Query: 337 YCIYYLVLGVLMFFTSYVQIACFESYA-ERLVHKLRQNYLKAILRQQIQWFD--KQQTGN 507
Y +++ V F + F YA E L K+R + I+RQ + +FD + G
Sbjct: 821 YAPLFILFAVANFLGWALH--GFYGYAGEHLTTKIRVLLFRQIMRQDMNFFDIPGRDAGT 878
Query: 508 LTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGA 687
L L+ D E V + G L VQ +G V F Y W + LV + PL++ G
Sbjct: 879 LAGMLSGDCEAVHQLWGPSIGLKVQTVCIVASGVVVSFIYQWKLALVALACMPLLI--GC 936
Query: 688 KMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIV 867
+++ M + + + I E SS+RTV S N ++ F L V +
Sbjct: 937 SLAERMMMNGYTKSKEGDTSDTIVTEALSSVRTVTSFNMKADRVEAFEATLRVEAPRSVK 996
Query: 868 KYCYMGIGVGFSNLCMYSSYALAFWYGSTLIIN-DPTFDRGLIFTVFFAVLSGSTSLGGA 1044
K G G + YS+YAL FWYGS LI + F +I + ++L G+ + G A
Sbjct: 997 KGIIAGSIYGATQFIYYSAYALCFWYGSKLIDRGEAQFTNVMIAST--SILFGAQNAGEA 1054
Query: 1045 LPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKG-DISFKDVHFRYPSRKDI 1221
A +A V VI+ P +D D KG D+ F+ V F Y +R
Sbjct: 1055 GAFATKLADAERSAKRVFSVIDRVPDVDIEQSGD--KDLGKGCDVDFQRVQFIYSARPKQ 1112
Query: 1222 HVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLR 1401
VL+ ++L G L+G +GCGKSTI+ +L RFYD G + ++G DL +++ R
Sbjct: 1113 VVLESVNLRFGDGTVNGLMGQTGCGKSTIIQMLARFYDRRSGLICVNGKDLSSLDIAEWR 1172
Query: 1402 EQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEK 1581
I +V QEP LF GT+ ENI+ E AT ++V EA ++A+ + I + PDGY T VG K
Sbjct: 1173 RNISVVLQEPNLFSGTVRENIRYAREDATDEEVEEAARLAHIHWEIVKWPDGYNTEVGYK 1232
Query: 1582 GVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALD--QAQAGRTTIIV 1755
G LSGGQKQR+AIAR L++ PK+LLLDEATSALD E +VQ ++ QA+ T++ +
Sbjct: 1233 GSALSGGQKQRVAIARGLLRRPKLLLLDEATSALDNVTEAKVQEGINAYQAKYEVTSVSI 1292
Query: 1756 AHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIF---YDM 1875
AHRL+TIR+ D+I + +G+I+E GSHEELM+ G + YD+
Sbjct: 1293 AHRLTTIRHCDQIILLDSGHIIEQGSHEELMALGGEYMMRYDL 1335
>gi|27368867|emb|CAD59591.1| MDR-like ABC transporter [Oryza sativa
(japonica cultivar-group)]
Length = 1255
Score = 667 bits (1722), Expect = 0.0
Identities = 407/1155 (35%), Positives = 624/1155 (53%), Gaps = 42/1155 (3%)
Frame = +1
Query: 400 CFESYAERLVHKLRQNYLKAILRQQIQWFD-------------KQQTGNLTARLTDDLER 540
C+ AER ++R+ YL+A+L Q++ +FD + T + + ++DD +
Sbjct: 78 CWTRTAERQASRMRRLYLEAVLSQEVAFFDAAPSSPSSPQAQAQATTFRVISTVSDDADA 137
Query: 541 VREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLI-VLSGAKMSKSMATRT 717
+++ LG+K +++ F V F ++W + L + F L+ V ++ MA
Sbjct: 138 IQDFLGEKLPMVLANATLFFGALAVSFVFAWRLALAGLPFTLLLFVTPSVLLAGRMAAAA 197
Query: 718 RVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVG 897
+ Y AG IA++ SSIRTV S +R ++RF A+ G+ + G +G
Sbjct: 198 GEARVAYEEAGGIAQQAVSSIRTVASYTAERRTVERFRGAVARSAALGVRQGLIKGAVIG 257
Query: 898 FSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTAR 1077
+ +Y+ ++ W GS L+I+ G +F ++ S+ ALP+L F A
Sbjct: 258 SMGV-IYAVWSFLSWIGSLLVIHLHA-QGGHVFVASICIVLAGMSIMMALPNLRYFIDAT 315
Query: 1078 GAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKA 1257
AAS + +I P ++ +G ++ ++G+I FKDVHF YPSR D VL G +L +
Sbjct: 316 AAASRMQEMIEMLPPLEGAEKKGATMERIRGEIVFKDVHFSYPSRPDTLVLNGFNLTISE 375
Query: 1258 GDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVL 1437
G + LVG SG GKST+++LLQRFY P G + +D + +NV LR QIG+VSQEPVL
Sbjct: 376 GATVGLVGGSGSGKSTVISLLQRFYSPDSGEISMDDHGIDTLNVEWLRSQIGLVSQEPVL 435
Query: 1438 FDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRI 1617
F +I ENI G+E A+ QVV A KMANA++FI +LP GY T VG+ G QLSGGQKQRI
Sbjct: 436 FATSIRENILFGDETASLKQVVAAAKMANAHEFIVKLPHGYETHVGQFGTQLSGGQKQRI 495
Query: 1618 AIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIF 1797
AIARALV++P+ILLLDEATSALD E+ER VQ ALD+A GRTT+IVAHRLST+R D I
Sbjct: 496 AIARALVRDPRILLLDEATSALDAESERTVQDALDRASVGRTTVIVAHRLSTLRKADTIA 555
Query: 1798 VFKAGNIVESGSHEELM-----SKQGIFYDMTXXXXXXXXXXE---------------AG 1917
V AG +VE+G+H+EL+ + G++ M +
Sbjct: 556 VLDAGRVVEAGTHDELLGMDDGGEGGVYARMVHLQKAPPVAAREERHRAVDVVESEMVSF 615
Query: 1918 KDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKAPPTSMFKIFKFNGDKVG 2097
+ +E + SA H I + + ++ S ++ K N +
Sbjct: 616 RSVEIMSAVSATEHRPSPAPSFCSVEHSTEIGRKLVDHGVARSRKPSKLRLLKMNRPEWK 675
Query: 2098 WXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPAD-QMQANVYFWCGMFVLMGITFFVGF 2274
+V P+++ + VY L D Q+++ + +F+ + +
Sbjct: 676 QALLGCVGAVVFGAVLPLYSYSLGSLPEVYFLADDGQIRSKTRLYSFLFLGIAVVCITAN 735
Query: 2275 FTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVR-YVF 2451
GE LT ++R + +L ++ ++D+ + + +C R AT + VR V
Sbjct: 736 IVQHYNFAVMGERLTERVRGQMLAKILSFEVGWFDEDENSSAAVCARLATQSSKVRSLVG 795
Query: 2452 TRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLL 2631
R+ +++ + T + W+ YF+ + + +
Sbjct: 796 DRMCLLVQAGATASLGFSLALAVSWRLATVMMAMQPLIIASFYFKKVLMAAMSKKAKKAQ 855
Query: 2632 EEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIF 2811
+ ++AS+AV + RT+ + + Q + Y + P N+ H+ G Q
Sbjct: 856 VQGSQLASEAVVNHRTITAFSSQRRMLRLYEAAQQGPKKDNVAHSWFSGFCLCLCQFSNT 915
Query: 2812 FMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAA-SLLF 2988
A A + G + + + P +++VFF + G++I + S D+ + A S+L
Sbjct: 916 GSMAVALWYGGKLMAKGLITPTHLFQVFFMLMTMGRVIADAGSLTSDLAQGGDAVRSVLD 975
Query: 2989 YLIEHPTPIDSLSDSGIV----KPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTV 3156
L PT D +D+ K I G I +NV F+YPTR + VL GF+L+I AGKTV
Sbjct: 976 TLDREPTIKDDDNDNERKKKKRKEIKGAIEFKNVHFSYPTRPEVAVLSGFSLEIGAGKTV 1035
Query: 3157 ALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCT 3336
ALVG SG GKST++GL+ERFY+ +G +++DG++IR+ +++ LR QV +VSQEPTLF T
Sbjct: 1036 ALVGPSGSGKSTVIGLIERFYDAQRGSVLVDGEDIRSYSLARLRSQVALVSQEPTLFSGT 1095
Query: 3337 IGENICYG-TNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAI 3513
I +NI YG + T E+ AA +AN H FI + GYDT VGE+G QLSGGQ+QRIA+
Sbjct: 1096 IRDNIAYGAAEEHATEDEVARAAALANAHGFISAMERGYDTRVGERGAQLSGGQRQRIAL 1155
Query: 3514 ARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIV 3693
ARA+++ +LLLDEATSALD SE++VQ+A+D +GRTC+V+AHRLST++ SD IA+V
Sbjct: 1156 ARAVLKDARILLLDEATSALDAASERLVQDAVDRMLRGRTCVVVAHRLSTVEKSDTIAVV 1215
Query: 3694 SEGKIVEKGTHDELI 3738
+G++ E+G H EL+
Sbjct: 1216 KDGRVAERGRHHELL 1230
Score = 348 bits (892), Expect = 7e-94
Identities = 219/592 (36%), Positives = 316/592 (52%), Gaps = 17/592 (2%)
Frame = +1
Query: 151 ITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEV 330
+ G V AV+ GA PL + LG + V+ A + + S+
Sbjct: 678 LLGCVGAVVFGAVLPLYSYSLGSLPEVYFLADDG--------------------QIRSKT 717
Query: 331 VKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGN- 507
Y +L + V+ + VQ F ERL ++R L IL ++ WFD+ + +
Sbjct: 718 RLYSFLFLGIAVVCITANIVQHYNFAVMGERLTERVRGQMLAKILSFEVGWFDEDENSSA 777
Query: 508 -LTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSG 684
+ ARL +VR +GD+ LLVQ A G+ + SW + VMM PLI+ S
Sbjct: 778 AVCARLATQSSKVRSLVGDRMCLLVQAGATASLGFSLALAVSWRLATVMMAMQPLIIASF 837
Query: 685 AKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGI 864
MA ++ ++ +A E + RT+ + + +R L R Y A + G +
Sbjct: 838 YFKKVLMAAMSKKAKKAQVQGSQLASEAVVNHRTITAFSSQRRML-RLYEAAQQGPKKDN 896
Query: 865 VKYCYMGIGVGFSN-LCMYS---SYALAFWYGSTLIIND---PTFDRGLIFTVFFAVLSG 1023
V + + GF LC +S S A+A WYG L+ PT +F VFF +++
Sbjct: 897 VAHSWFS---GFCLCLCQFSNTGSMAVALWYGGKLMAKGLITPTH----LFQVFFMLMTM 949
Query: 1024 STSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDN----MKGDISFKDV 1191
+ A + A +VL ++ P I + +KG I FK+V
Sbjct: 950 GRVIADAGSLTSDLAQGGDAVRSVLDTLDREPTIKDDDNDNERKKKKRKEIKGAIEFKNV 1009
Query: 1192 HFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVD 1371
HF YP+R ++ VL G SLE+ AG +ALVG SG GKST++ L++RFYD +G VL+DG D
Sbjct: 1010 HFSYPTRPEVAVLSGFSLEIGAGKTVALVGPSGSGKSTVIGLIERFYDAQRGSVLVDGED 1069
Query: 1372 LREVNVHSLREQIGIVSQEPVLFDGTIYENIKMG--NEHATHDQVVEACKMANANDFIKR 1545
+R ++ LR Q+ +VSQEP LF GTI +NI G EHAT D+V A +ANA+ FI
Sbjct: 1070 IRSYSLARLRSQVALVSQEPTLFSGTIRDNIAYGAAEEHATEDEVARAAALANAHGFISA 1129
Query: 1546 LPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQ 1725
+ GY TRVGE+G QLSGGQ+QRIA+ARA++K+ +ILLLDEATSALD +ER VQ A+D+
Sbjct: 1130 MERGYDTRVGERGAQLSGGQRQRIALARAVLKDARILLLDEATSALDAASERLVQDAVDR 1189
Query: 1726 AQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMS--KQGIFYDM 1875
GRT ++VAHRLST+ D I V K G + E G H EL++ + G +Y++
Sbjct: 1190 MLRGRTCVVVAHRLSTVEKSDTIAVVKDGRVAERGRHHELLAVGRAGTYYNL 1241
Score = 313 bits (803), Expect = 2e-83
Identities = 194/507 (38%), Positives = 281/507 (55%), Gaps = 14/507 (2%)
Frame = +1
Query: 2260 FFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYD-----------DLRHGTGKL 2406
F G C R E ++R + +L Q++AF+D + T ++
Sbjct: 68 FSSGAVDKGLCWTRTAERQASRMRRLYLEAVLSQEVAFFDAAPSSPSSPQAQAQATTFRV 127
Query: 2407 CTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYF 2583
+ + DA ++ ++ +LP+VLA+ GAL + F + W+ +
Sbjct: 128 ISTVSDDADAIQDFLGEKLPMVLANATLFFGALAVSFVFAWRLALAGLPFTLLLFVTPSV 187
Query: 2584 EMQMRFGKQIRDTQLL-EEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLK 2760
+ R + ++ EEAG +A QAV IRTV S + + + + ++
Sbjct: 188 LLAGRMAAAAGEARVAYEEAGGIAQQAVSSIRTVASYTAERRTVERFRGAVARSAALGVR 247
Query: 2761 HAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTS 2940
GAV S +I+ +++ ++GS+ V Q V+ I G I
Sbjct: 248 QGLIKGAVIG-SMGVIYAVWSFLSWIGSLLVIHLHAQGGHVFVASICIVLAGMSIMMALP 306
Query: 2941 FIPDVVKARLAASLLFYLIEHPTPIDSLSDSGI-VKPITGNISIRNVFFNYPTRKDTKVL 3117
+ + A AAS + +IE P++ G ++ I G I ++V F+YP+R DT VL
Sbjct: 307 NLRYFIDATAAASRMQEMIEMLPPLEGAEKKGATMERIRGEIVFKDVHFSYPSRPDTLVL 366
Query: 3118 QGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQV 3297
GF L I G TV LVG SG GKST++ LL+RFY+ D G I +D I LN+ LR Q+
Sbjct: 367 NGFNLTISEGATVGLVGGSGSGKSTVISLLQRFYSPDSGEISMDDHGIDTLNVEWLRSQI 426
Query: 3298 CIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGT 3477
+VSQEP LF +I ENI +G + + +++V AAKMAN H FI+ LP GY+THVG+ GT
Sbjct: 427 GLVSQEPVLFATSIRENILFG-DETASLKQVVAAAKMANAHEFIVKLPHGYETHVGQFGT 485
Query: 3478 QLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRL 3657
QLSGGQKQRIAIARALVR P +LLLDEATSALD ESE+ VQ+ALD A GRT +++AHRL
Sbjct: 486 QLSGGQKQRIAIARALVRDPRILLLDEATSALDAESERTVQDALDRASVGRTTVIVAHRL 545
Query: 3658 STIQNSDVIAIVSEGKIVEKGTHDELI 3738
ST++ +D IA++ G++VE GTHDEL+
Sbjct: 546 STLRKADTIAVLDAGRVVEAGTHDELL 572
>gi|46129276|ref|XP_388999.1| hypothetical protein FG08823.1
[Gibberella zeae PH-1]
gi|42548720|gb|EAA71563.1| hypothetical protein FG08823.1 [Gibberella
zeae PH-1]
Length = 1263
Score = 667 bits (1721), Expect = 0.0
Identities = 424/1244 (34%), Positives = 650/1244 (52%), Gaps = 21/1244 (1%)
Frame = +1
Query: 115 FYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGL 294
F + +D +L + + ++ GA P++AI+ G T + +DF G +V+P
Sbjct: 36 FQFADRLDWVLNVISLICSIASGAAMPVMAILFGKAT-----GRLADF--GGGSVDP--- 85
Query: 295 VPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQ 474
DEF SEV + +++ L V F +YV R LRQ L+ +LR +
Sbjct: 86 -----DEFKSEVNSFVLWFTYLFVGKFVLAYVATTAITISGVRTTRVLRQRVLEKLLRTE 140
Query: 475 IQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMM 654
I +FD G+ +LT ++ R+ +G+ +K +LLVQ A F + + V W + L+ +
Sbjct: 141 IWYFDTANVGSPATQLTTNVTRINQGIAEKLSLLVQGLAMFASAFVVAIAVQWKLALITL 200
Query: 655 GFAPLIVL-SGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFY 831
PL L G MS +V ++ A A+E +SIRTVH+ H R +R+
Sbjct: 201 TVVPLFFLIMGVFMSLDAPIEAKVTG-IHSQANVFAQEVMASIRTVHAFWAHGRMSERYD 259
Query: 832 NALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFA 1011
N L+ G K GI + CMYS ALAFW G + + G +FTV +
Sbjct: 260 NYLKEAHTHGKKKSLLYGIMSSSTYFCMYSGNALAFWQGFRMYRSGEIDSVGTVFTVVLS 319
Query: 1012 VLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDV 1191
VL S+S+G P + + AAS + ++ + +DP S EG + + G+I +++
Sbjct: 320 VLLASSSIGLLYPQIPALVNGAAAASELFQIFDKPSLLDPLSNEGQVPEACNGNIQVENI 379
Query: 1192 HFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVD 1371
F YPSR + VLK ISL++ AG A VG+SG GKSTI+ LL+R+Y P+ GR+L+DGVD
Sbjct: 380 SFSYPSRPNTQVLKDISLDIPAGKTTAFVGASGSGKSTIIGLLERWYLPSSGRLLLDGVD 439
Query: 1372 LREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHA--------THDQVVEACKMANA 1527
+ +NV R Q+ +V QEPVLF GT++EN+ G + V EAC+ + A
Sbjct: 440 ISTLNVKWFRSQMALVQQEPVLFRGTVFENVSKGFTDSQKALPLKEQRTLVQEACEASYA 499
Query: 1528 NDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREV 1707
+DFI+ L GY T +GE+G LSGGQKQRIAIAR++V NPKILLLDEATSALD AER V
Sbjct: 500 HDFIQNLEHGYDTYLGERGGTLSGGQKQRIAIARSVVSNPKILLLDEATSALDPNAERIV 559
Query: 1708 QGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXX 1887
Q AL + RTT+++AHRLSTIR+ D I V G +VE G+H++L++ + +
Sbjct: 560 QKALSRVSQQRTTLVIAHRLSTIRDADSIVVLSNGQVVEQGTHDDLLALDSHYARLIRAQ 619
Query: 1888 XXXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKAPP----T 2055
G++I+ IS + E +E K +
Sbjct: 620 NLSV----VGREIKAGISADENPDAFDTEDEVRRVITAQTHKYRDVEGQESKPKDRSILS 675
Query: 2056 SMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLPADQMQANVYFWCG 2235
S+F + K + + P AL+++ I +S AD ++V F+
Sbjct: 676 SIFLVVKEQKALRLYIITSALCCTIAAATWPGQALLFSRIITAFS--ADTSASDVNFYAL 733
Query: 2236 MFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTR 2415
MF ++ + V + ++++ + R E F ++ DI F+D + +G L +
Sbjct: 734 MFFVIALGNLVCYGIIGYIANHVSQTISYQYRLELFTRMVGLDIEFFDRPENSSGALAST 793
Query: 2416 FATDAPNVRYVF-TRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMG-GYFEM 2589
++ +++ + + V++ V I + + YGW+ MG GYF++
Sbjct: 794 LSSIPTHLQELLGLNIFVIVVMFVNITASSILAIAYGWKLALVMVFAALPLLMGSGYFKV 853
Query: 2590 QMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAH 2769
++ + E+ +AS+AV +RTV SL + F Y + L +K
Sbjct: 854 RLESKLHAGNEARFRESASLASEAVSSLRTVASLTAETDFITQYSDTLSSIVMKTIKSLS 913
Query: 2770 TYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIP 2949
+AFSQS+ F + A F+ GS + + +F + F GQ + +
Sbjct: 914 VSMIAYAFSQSIEFLVMALGFWYGSRLMASGEYTSEQFFLIFMGVLFAGQAASQLFANLT 973
Query: 2950 DVVKARLAASLLFYLIEHPTPIDSLSDSGIVKP-ITGNISIRNVFFNYPTRKDTKVLQGF 3126
+ A+ AA+ LF L E I +D+ P I + +V F Y +R TKVLQG
Sbjct: 974 SLTMAKGAANYLFNLREEKAVIRETNDNKDKCPDFDQPIGVTDVHFQYKSR-STKVLQGL 1032
Query: 3127 TLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIV 3306
++DI + VA+VG SGCGKST++ LLER+Y+ G I + +I++++ R Q+ IV
Sbjct: 1033 SMDISPSQFVAVVGPSGCGKSTLISLLERYYDATTGKICVGEQDIKDMSPRQFRSQMSIV 1092
Query: 3307 SQEPTLFDCTIGENICYGTNRNV---TYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGT 3477
QEP L++ ++ ENI G + T + + EAA+ A+I F LP+G+DT G +GT
Sbjct: 1093 QQEPILYEGSVRENILMGLEGDATDKTDERLNEAARQADILEFASSLPEGFDTPCGPRGT 1152
Query: 3478 QLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVI--AH 3651
SGGQ+QRIAIARAL+R P +LLLDEATSALDT SEK+VQEAL+ ++ C VI AH
Sbjct: 1153 AFSGGQRQRIAIARALIRKPKLLLLDEATSALDTHSEKLVQEALEQTRKESGCSVIAVAH 1212
Query: 3652 RLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRI 3783
RLSTI+++D+I ++ GK+ E GTH++L + +Y C+ Q +
Sbjct: 1213 RLSTIRDADIIFVLVGGKVAEVGTHEDLQARRGVYADMCQAQSL 1256
Score = 299 bits (766), Expect = 3e-79
Identities = 201/607 (33%), Positives = 314/607 (51%), Gaps = 21/607 (3%)
Frame = +1
Query: 2026 EVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXS--VTPVFALVYAEI------FN 2181
EVE+ +A + +++ F+F D++ W S PV A+++ + F
Sbjct: 22 EVEK-QAQLSDLWRAFQF-ADRLDWVLNVISLICSIASGAAMPVMAILFGKATGRLADFG 79
Query: 2182 VYSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQ 2361
S+ D+ ++ V + F + + FV + + + G T LR + LLR
Sbjct: 80 GGSVDPDEFKSEVNSFVLWFTYLFVGKFVLAYVATTAITISGVRTTRVLRQRVLEKLLRT 139
Query: 2362 DIAFYDDLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIVTICGALGIGFYYGWQXXX 2538
+I ++D G T+ T+ + + +L +++ + A + W+
Sbjct: 140 EIWYFDTAN--VGSPATQLTTNVTRINQGIAEKLSLLVQGLAMFASAFVVAIAVQWKLAL 197
Query: 2539 XXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFT 2718
+ M + + + T + +A A + + IRTVH+ +
Sbjct: 198 ITLTVVPLFFLIMGVFMSLDAPIEAKVTGIHSQANVFAQEVMASIRTVHAFWAHGRMSER 257
Query: 2719 YCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMY---AAAFYLGSIFVNQQAMQPID-VY 2886
Y YL+E K + YG + S S F MY A AF+ G + + V+
Sbjct: 258 YDNYLKEAHTHGKKKSLLYGIM---SSSTYFCMYSGNALAFWQGFRMYRSGEIDSVGTVF 314
Query: 2887 RVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIV-KPITGNI 3063
V ++ IG IP +V AAS LF + + P+ +D LS+ G V + GNI
Sbjct: 315 TVVLSVLLASSSIGLLYPQIPALVNGAAAASELFQIFDKPSLLDPLSNEGQVPEACNGNI 374
Query: 3064 SIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIM 3243
+ N+ F+YP+R +T+VL+ +LDI AGKT A VG SG GKSTI+GLLER+Y G ++
Sbjct: 375 QVENISFSYPSRPNTQVLKDISLDIPAGKTTAFVGASGSGKSTIIGLLERWYLPSSGRLL 434
Query: 3244 IDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYG---TNRNVTYQE----IVEAA 3402
+DG +I LN+ R Q+ +V QEP LF T+ EN+ G + + + +E + EA
Sbjct: 435 LDGVDISTLNVKWFRSQMALVQQEPVLFRGTVFENVSKGFTDSQKALPLKEQRTLVQEAC 494
Query: 3403 KMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTE 3582
+ + H+FI L GYDT++GE+G LSGGQKQRIAIAR++V +P +LLLDEATSALD
Sbjct: 495 EASYAHDFIQNLEHGYDTYLGERGGTLSGGQKQRIAIARSVVSNPKILLLDEATSALDPN 554
Query: 3583 SEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQK 3762
+E+IVQ+AL Q RT LVIAHRLSTI+++D I ++S G++VE+GTHD+L+ Y +
Sbjct: 555 AERIVQKALSRVSQQRTTLVIAHRLSTIRDADSIVVLSNGQVVEQGTHDDLLALDSHYAR 614
Query: 3763 FCETQRI 3783
Q +
Sbjct: 615 LIRAQNL 621
>gi|159363|gb|AAA02977.1| P-glycoprotein
Length = 1341
Score = 665 bits (1717), Expect = 0.0
Identities = 430/1237 (34%), Positives = 643/1237 (51%), Gaps = 28/1237 (2%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
IF Y D +L+I GT+ AV GAG PL + + G + T D + GV +V
Sbjct: 121 IFRYADTADRVLMIVGTIFAVCSGAGTPLFSFIFGRIAT--------DLMSGVGSVE--- 169
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
K + + +G+ MF + C+ A R ++R N+ +A+LRQ
Sbjct: 170 ----------LSAAKTSLIMVYVGIGMFVACGGHVLCWTVAASRQEGRIRLNFFRAVLRQ 219
Query: 472 QIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVM 651
I W D+ G LTAR+T D ++ G+ DK + + A + GY GF +SW +TLVM
Sbjct: 220 DIGWHDEHSPGELTARMTGDTRVIQNGINDKLSQGIMNGAMGIIGYIAGFVFSWDVTLVM 279
Query: 652 MGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFY 831
+G P I++ A + ++ T ++ +A AG++A E +IRTV EL RF
Sbjct: 280 VGMMPFIIVMAAIIGNIVSKMTESSRKHFAKAGSLATEVMENIRTVQVFGREDYELQRFA 339
Query: 832 NALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFA 1011
A+ + GI K + +Y SY +AF++GS L+ D I + F A
Sbjct: 340 EAVLYAQDRGIRKEFAGNLSAAVIMALVYLSYTIAFFFGSYLV-EWGRRDMADIISTFLA 398
Query: 1012 VLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDV 1191
VL GS LG P +F +R AA + + I+ P +D G+ V K I F++V
Sbjct: 399 VLMGSFGLGFVAPSATAFTESRAAAYEIFKAIDRVPPVD-IDAGGVPVTGFKQSIEFRNV 457
Query: 1192 HFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVD 1371
F YP+R D+ + + ++L +K G K+A GSSGCGKS+++ L+QRFYDP G VL DGVD
Sbjct: 458 RFSYPTRPDMILFRDLNLTIKCGQKVAFSGSSGCGKSSMIGLIQRFYDPVGGAVLCDGVD 517
Query: 1372 LREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLP 1551
LRE+ +H R+QIGIVSQEP LF GT+ EN+++G +AT ++V+EAC+ AN +D I LP
Sbjct: 518 LRELCLHDWRDQIGIVSQEPNLFAGTMMENVRVGKPNATEEEVIEACRQANVHDTIMSLP 577
Query: 1552 DGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQ-- 1725
D Y T VG G QLSGGQKQRIAIARALVK P +LLLDEATSALD ++E EVQ +LDQ
Sbjct: 578 DQYNTPVGAVGSQLSGGQKQRIAIARALVKRPPVLLLDEATSALDRKSEMEVQRSLDQLM 637
Query: 1726 AQAGRTTIIVAHRLSTIRNVDRIFVFK-----AGNIVESGSHEELMSKQGIFYDMTXXXX 1890
+ G T I++AHRL+TIRNVD I+ K I ESG+ +ELM G F M
Sbjct: 638 QRGGMTVIVIAHRLATIRNVDCIYYVKYDGAEGSKITESGTFDELMELGGEFAAMARIQG 697
Query: 1891 XXXXXXEAGKDIED----------TISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEEC 2040
+G +D + E+A + L I +LA+ E
Sbjct: 698 VSTGDARSGARGQDGGKANDFLNAILDEAALAQL--DEEAPRTARQKVPIEELAK--WEV 753
Query: 2041 KAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNV---YSL--PADQ 2205
++ N DK + P ++ + V YS+ +Q
Sbjct: 754 NGVSVGFRRLMGMNKDKSWAVALGILGSAVGGAARPTSTILMGYMLRVLGEYSVNKNVEQ 813
Query: 2206 MQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDL 2385
+++ + +F++ + F+G+ G GE LT K+R F+ ++RQD+ F+D
Sbjct: 814 LRSGTNLYAPLFIVFAVANFLGWILH-GFYGYAGEHLTTKIRVLLFRQIMRQDMNFFDIP 872
Query: 2386 RHGTGKLCTRFATDAPNVRYVFTRLPVVLASIVTIC---GALGIGFYYGWQXXXXXXXXX 2556
G L + D V ++ P + + T+C + + F Y W+
Sbjct: 873 GRDAGTLAGMLSGDCEAVHQLWG--PSIGLKVQTVCIVASGIVVSFIYQWKLALVALACM 930
Query: 2557 XXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLR 2736
E M G ++ + + + ++A+ +RTV S N + + LR
Sbjct: 931 PLLIGCSLAERMMMNG--YTKSKEGDTSDTIVTEALSSVRTVTSFNMKADRVEAFEATLR 988
Query: 2737 EPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCG 2916
++K G+++ +Q + + YA F+ GS +++ Q DV +I F
Sbjct: 989 VEVPRSVKKGIIAGSIYGATQFIYYSAYALCFWYGSKLIDRGEAQFTDVMIASMSILFGA 1048
Query: 2917 QMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITG-NISIRNVFFNYP 3093
Q G +F + A +A +F +I+ +D + SG G ++ R V F Y
Sbjct: 1049 QNAGEAGAFATKLADAERSAKRVFSVIDRVPDVD-IEQSGDKDLGKGCDVDFRKVQFIYS 1107
Query: 3094 TRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLN 3273
R VL L G L+G +GCGKSTI+ +L RFY++ G+I ++G ++ +L+
Sbjct: 1108 ARPKQVVLASVNLRFGDGMANGLMGQTGCGKSTIIQMLARFYDRRSGLICVNGKDLSSLD 1167
Query: 3274 ISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYD 3453
I+ R + +V QEP LF T+ ENI Y + T +E+ EAA++A+IH I+ PDGY+
Sbjct: 1168 IAEWRRNISVVLQEPNLFSGTVRENIRY-AREDATDEEVEEAARLAHIHWEIMKWPDGYN 1226
Query: 3454 THVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDA--AKQG 3627
T VG KG+ LSGGQKQR+AIAR L+R P +LLLDEATSALD+ +E VQE ++ AK G
Sbjct: 1227 TEVGYKGSALSGGQKQRVAIARGLLRRPKLLLLDEATSALDSVTEAKVQEGINVYQAKYG 1286
Query: 3628 RTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELI 3738
T + IAHRL+TI++ D I ++ G I+E+G+H+EL+
Sbjct: 1287 VTSVSIAHRLTTIRHCDQIILLDSGHIIEQGSHEELM 1323
Score = 303 bits (776), Expect = 2e-80
Identities = 203/586 (34%), Positives = 299/586 (50%), Gaps = 13/586 (2%)
Frame = +1
Query: 157 GTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEVVK 336
G + + + GA P I++G M V +G +VN ++++ S
Sbjct: 777 GILGSAVGGAARPTSTILMGYMLRV----------LGEYSVNK------NVEQLRSGTNL 820
Query: 337 YCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD--KQQTGNL 510
Y ++V V F ++ + E L K+R + I+RQ + +FD + G L
Sbjct: 821 YAPLFIVFAVANFL-GWILHGFYGYAGEHLTTKIRVLLFRQIMRQDMNFFDIPGRDAGTL 879
Query: 511 TARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAK 690
L+ D E V + G L VQ +G V F Y W + LV + PL++ G
Sbjct: 880 AGMLSGDCEAVHQLWGPSIGLKVQTVCIVASGIVVSFIYQWKLALVALACMPLLI--GCS 937
Query: 691 MSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVK 870
+++ M + + + I E SS+RTV S N ++ F L V + K
Sbjct: 938 LAERMMMNGYTKSKEGDTSDTIVTEALSSVRTVTSFNMKADRVEAFEATLRVEVPRSVKK 997
Query: 871 YCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGL-----IFTVFFAVLSGSTSL 1035
G G + YS+YAL FWYGS LI DRG + ++L G+ +
Sbjct: 998 GIIAGSIYGATQFIYYSAYALCFWYGSKLI------DRGEAQFTDVMIASMSILFGAQNA 1051
Query: 1036 GGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKG-DISFKDVHFRYPSR 1212
G A A +A V VI+ P +D D KG D+ F+ V F Y +R
Sbjct: 1052 GEAGAFATKLADAERSAKRVFSVIDRVPDVDIEQSGD--KDLGKGCDVDFRKVQFIYSAR 1109
Query: 1213 KDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVH 1392
VL ++L G L+G +GCGKSTI+ +L RFYD G + ++G DL +++
Sbjct: 1110 PKQVVLASVNLRFGDGMANGLMGQTGCGKSTIIQMLARFYDRRSGLICVNGKDLSSLDIA 1169
Query: 1393 SLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRV 1572
R I +V QEP LF GT+ ENI+ E AT ++V EA ++A+ + I + PDGY T V
Sbjct: 1170 EWRRNISVVLQEPNLFSGTVRENIRYAREDATDEEVEEAARLAHIHWEIMKWPDGYNTEV 1229
Query: 1573 GEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALD--QAQAGRTT 1746
G KG LSGGQKQR+AIAR L++ PK+LLLDEATSALD+ E +VQ ++ QA+ G T+
Sbjct: 1230 GYKGSALSGGQKQRVAIARGLLRRPKLLLLDEATSALDSVTEAKVQEGINVYQAKYGVTS 1289
Query: 1747 IIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIF---YDM 1875
+ +AHRL+TIR+ D+I + +G+I+E GSHEELM+ G + YD+
Sbjct: 1290 VSIAHRLTTIRHCDQIILLDSGHIIEQGSHEELMALGGEYMMRYDL 1335
Score = 275 bits (704), Expect = 5e-72
Identities = 196/562 (34%), Positives = 289/562 (50%), Gaps = 15/562 (2%)
Frame = +1
Query: 2143 TPVFALVYAEIFNVYSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTM 2322
TP+F+ ++ I ++ + + V +GI FV C
Sbjct: 147 TPLFSFIFGRIATDLMSGVGSVELSAAKTSLIMVYVGIGMFVACGGHVLCWTVAASRQEG 206
Query: 2323 KLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVFTRLPVVLASIVTICGAL 2502
++R F+ +LRQDI ++D+ H G+L R D R + + L+ + + GA+
Sbjct: 207 RIRLNFFRAVLRQDIGWHDE--HSPGELTARMTGDT---RVIQNGINDKLSQGI-MNGAM 260
Query: 2503 GI-----GFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVE 2667
GI GF + W + + + +AG +A++ +E
Sbjct: 261 GIIGYIAGFVFSWDVTLVMVGMMPFIIVMAAIIGNIVSKMTESSRKHFAKAGSLATEVME 320
Query: 2668 HIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSI 2847
+IRTV R++ + E + + ++ A +L++ Y AF+ GS
Sbjct: 321 NIRTVQVFGREDYELQRFAEAVLYAQDRGIRKEFAGNLSAAVIMALVYLSYTIAFFFGSY 380
Query: 2848 FVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLS 3027
V D+ F A+ +G ++R AA +F I+ P+D
Sbjct: 381 LVEWGRRDMADIISTFLAVLMGSFGLGFVAPSATAFTESRAAAYEIFKAIDRVPPVDI-- 438
Query: 3028 DSGIVKPITG---NISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIM 3198
D+G V P+TG +I RNV F+YPTR D + + L IK G+ VA G SGCGKS+++
Sbjct: 439 DAGGV-PVTGFKQSIEFRNVRFSYPTRPDMILFRDLNLTIKCGQKVAFSGSSGCGKSSMI 497
Query: 3199 GLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVT 3378
GL++RFY+ G ++ DG ++R L + R+Q+ IVSQEP LF T+ EN+ G N T
Sbjct: 498 GLIQRFYDPVGGAVLCDGVDLRELCLHDWRDQIGIVSQEPNLFAGTMMENVRVG-KPNAT 556
Query: 3379 YQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDE 3558
+E++EA + AN+H+ I+ LPD Y+T VG G+QLSGGQKQRIAIARALV+ P VLLLDE
Sbjct: 557 EEEVIEACRQANVHDTIMSLPDQYNTPVGAVGSQLSGGQKQRIAIARALVKRPPVLLLDE 616
Query: 3559 ATSALDTESEKIVQEALDAAKQ--GRTCLVIAHRLSTIQNSDVIAIV----SEG-KIVEK 3717
ATSALD +SE VQ +LD Q G T +VIAHRL+TI+N D I V +EG KI E
Sbjct: 617 ATSALDRKSEMEVQRSLDQLMQRGGMTVIVIAHRLATIRNVDCIYYVKYDGAEGSKITES 676
Query: 3718 GTHDELIRKSEIYQKFCETQRI 3783
GT DEL+ E+ +F RI
Sbjct: 677 GTFDELM---ELGGEFAAMARI 695
>gi|37806003|dbj|BAC99416.1| putative MDR-like ABC transporter [Oryza
sativa (japonica cultivar-group)]
gi|37806247|dbj|BAC99764.1| putative MDR-like ABC transporter [Oryza
sativa (japonica cultivar-group)]
Length = 1261
Score = 662 bits (1708), Expect = 0.0
Identities = 427/1255 (34%), Positives = 661/1255 (52%), Gaps = 32/1255 (2%)
Frame = +1
Query: 109 GIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPE 288
G+ Y VD LL+ GTV ++IHG FP+ ++LG + G + + E
Sbjct: 43 GLLCYADAVDWLLMALGTVGSIIHGMAFPVGYLLLGKALDAY----------GTNINDQE 92
Query: 289 GLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILR 468
G+V +VV + ++Y+ L V+I+C+ +ER + ++R +L+++L
Sbjct: 93 GMVHALY-----KVVPF-VWYMAAATLP--AGMVEISCWIYSSERQLARMRLAFLRSVLN 144
Query: 469 QQIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTL 645
Q++ FD T + +T+ + +++ +G+K V F+ F AG + F W + L
Sbjct: 145 QEVGAFDTDLTTAKIITGVTNHMSVIQDAIGEKLGHFVASFSTFFAGIIIAFASCWEVAL 204
Query: 646 VMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDR 825
+ PLI++ GA +K M + + A +I E+T S I+TV S G KR +
Sbjct: 205 LSFLVIPLILVIGATYTKQMNGISLSRNAIVSEATSIVEQTLSHIKTVFSFVGEKRAMRS 264
Query: 826 FY----NALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLI 993
F N ++ ++ ++K GIG+G + S+AL W G+ + + G I
Sbjct: 265 FVRCMDNQYKLSKKEAVIK----GIGLGLFQAVTFCSWALMVWIGAVAVTSRKATGGGTI 320
Query: 994 FTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGD 1173
+ ++L G+ S+ A P L +F A+ A V +VI P I Y G ++ + G+
Sbjct: 321 AAIM-SILFGAISITYAAPDLQTFNQAKAAGKEVFKVIKRKPSIS-YEKHGSVLGKVHGE 378
Query: 1174 ISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRV 1353
I F+ VHF YPSR+D +L+G SL + AG +ALVGSSGCGKST+++LLQRFYDPT G +
Sbjct: 379 IKFRRVHFAYPSRQDKPILQGFSLSIPAGKVVALVGSSGCGKSTVISLLQRFYDPTSGSI 438
Query: 1354 LIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAND 1533
LIDG ++++++ SLR I VSQEP LF GTI +N+++G A D++ +A + AN +
Sbjct: 439 LIDGHSIKKLDLESLRRNIASVSQEPSLFSGTIKDNLRIGKMDANDDEITKAARTANVHS 498
Query: 1534 FIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQG 1713
FI +LP+ Y T VGE+GVQLSGGQKQRIAIARA++K+P ILLLDEATSALD+E+E+ VQ
Sbjct: 499 FISKLPNEYLTEVGERGVQLSGGQKQRIAIARAMLKDPPILLLDEATSALDSESEKLVQD 558
Query: 1714 ALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTX---- 1881
AL++A +GRT I++AHR+STI N D I V + G + ++G+H+EL+ K + ++
Sbjct: 559 ALEKAMSGRTVILIAHRMSTIVNADTIVVVENGKVAQTGTHQELIEKSTFYSNVCSMQNI 618
Query: 1882 -XXXXXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQL--AEEVEECKAPP 2052
+ IED I E L + QL + +E +
Sbjct: 619 EKEAGTRVASSSDNVIEDEIDEVYDRQL------SPKQGQQNKLEQLNSKQPKQEVRKEI 672
Query: 2053 TSMFKI-FKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEI-FNVYSLPADQMQAN--- 2217
F++ + D + P+F I Y L A + +
Sbjct: 673 HPFFRLWYGLQKDDIAKILLGSSSAAISGISKPLFGYFIMTIGVAYYDLDAKRKVSKYSL 732
Query: 2218 VYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGT 2397
++F G+ L F G GE LR F ++LR ++ +++ ++G
Sbjct: 733 IFFTAGVITLASNIF------QHYIYGVVGEKAMKILREAIFSSVLRNELGWFEKPKNGV 786
Query: 2398 GKLCTRFATDAPNVRYVFT-RLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMG 2574
G L +R +D V+ + + R+ V++ I +I A + Y W+ +G
Sbjct: 787 GFLTSRIVSDTSTVKTIISDRMAVIVQCISSILIATVVSMYVNWRMGLVSWAVMPCHFIG 846
Query: 2575 GYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTN 2754
G + + G +E +AS+A +IRTV S +++ L+EP
Sbjct: 847 GLIQAKAAKGFYGDSAIAHQELVSLASEAASNIRTVASFVYEDEIIKKAELSLQEPMRVT 906
Query: 2755 LKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNT 2934
+ YG V S L +A A + ++ V ++ + R + S I
Sbjct: 907 KIESMKYGVVQGISLCLWNIAHAVALWYTTVLVQRKQASFENSIRSYQIFSLTVPSITEL 966
Query: 2935 TSFIPDVVKARLAASLLFYLIEHPTPI-----DSLSDSGIVKPITGNISIRNVFFNYPTR 3099
+ IP V+ A + F +++ T I ++ SD ++ G ++V FNYP+R
Sbjct: 967 WTLIPMVMSAIAVLNPAFEMLDRDTQIVPDRPENPSDGWLM----GRTEFQDVSFNYPSR 1022
Query: 3100 KDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNIS 3279
+ +L GF+L I+ G+ VALVG SG GKS+++ LL RFY+ +G ++ID NI++ N+
Sbjct: 1023 PEVTILDGFSLVIEPGQRVALVGPSGAGKSSVLALLLRFYDPQRGRVLIDNKNIKDYNLR 1082
Query: 3280 SLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTH 3459
LR+Q+ +V QEP LF+ +I +NI YG + + EI++AA ANIH FI LP GYDT
Sbjct: 1083 WLRKQIGLVQQEPILFNSSIRDNISYG-SEETSETEIIQAAMEANIHEFISSLPKGYDTV 1141
Query: 3460 VGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDA-------- 3615
VGEKG+QLSGGQKQRIAIAR L++ P +LLLDEATSALD ESE++V +L A
Sbjct: 1142 VGEKGSQLSGGQKQRIAIARTLLKRPVILLLDEATSALDGESERVVMSSLGAKDWKDRNE 1201
Query: 3616 AKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSE-IYQKFCETQ 3777
T + +AHRLST+ NSD I ++ GK+VE G H LI + +Y + Q
Sbjct: 1202 GSSKITSITVAHRLSTVINSDTIVVMERGKVVELGNHHTLITADDGVYSRLFHLQ 1256
Score = 305 bits (782), Expect = 4e-81
Identities = 181/501 (36%), Positives = 271/501 (53%), Gaps = 2/501 (0%)
Frame = +1
Query: 2287 NCLGRCGESLTMKLRFEAFKNLLRQDIAFYD-DLRHGTGKLCTRFATDAPNVR-YVFTRL 2460
+C E ++R +++L Q++ +D DL T K+ T ++ + +L
Sbjct: 121 SCWIYSSERQLARMRLAFLRSVLNQEVGAFDTDLT--TAKIITGVTNHMSVIQDAIGEKL 178
Query: 2461 PVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEA 2640
+AS T + I F W+ + G + G + ++ EA
Sbjct: 179 GHFVASFSTFFAGIIIAFASCWEVALLSFLVIPLILVIGATYTKQMNGISLSRNAIVSEA 238
Query: 2641 GKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMY 2820
+ Q + HI+TV S +++ ++ + + + K A G Q++ F +
Sbjct: 239 TSIVEQTLSHIKTVFSFVGEKRAMRSFVRCMDNQYKLSKKEAVIKGIGLGLFQAVTFCSW 298
Query: 2821 AAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIE 3000
A ++G++ V + +I F I + +A+ A +F +I+
Sbjct: 299 ALMVWIGAVAVTSRKATGGGTIAAIMSILFGAISITYAAPDLQTFNQAKAAGKEVFKVIK 358
Query: 3001 HPTPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGC 3180
I ++ + G I R V F YP+R+D +LQGF+L I AGK VALVG SGC
Sbjct: 359 RKPSISYEKHGSVLGKVHGEIKFRRVHFAYPSRQDKPILQGFSLSIPAGKVVALVGSSGC 418
Query: 3181 GKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYG 3360
GKST++ LL+RFY+ G I+IDG +I+ L++ SLR + VSQEP+LF TI +N+ G
Sbjct: 419 GKSTVISLLQRFYDPTSGSILIDGHSIKKLDLESLRRNIASVSQEPSLFSGTIKDNLRIG 478
Query: 3361 TNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPS 3540
+ EI +AA+ AN+H+FI LP+ Y T VGE+G QLSGGQKQRIAIARA+++ P
Sbjct: 479 -KMDANDDEITKAARTANVHSFISKLPNEYLTEVGERGVQLSGGQKQRIAIARAMLKDPP 537
Query: 3541 VLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKG 3720
+LLLDEATSALD+ESEK+VQ+AL+ A GRT ++IAHR+STI N+D I +V GK+ + G
Sbjct: 538 ILLLDEATSALDSESEKLVQDALEKAMSGRTVILIAHRMSTIVNADTIVVVENGKVAQTG 597
Query: 3721 THDELIRKSEIYQKFCETQRI 3783
TH ELI KS Y C Q I
Sbjct: 598 THQELIEKSTFYSNVCSMQNI 618
Score = 303 bits (777), Expect = 2e-80
Identities = 198/598 (33%), Positives = 319/598 (53%), Gaps = 16/598 (2%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNP 285
+ ++Y Q D+ ++ G+ +A I G PL F++ +
Sbjct: 676 FRLWYGLQKDDIAKILLGSSSAAISGISKPLFGY----------------FIMTI----- 714
Query: 286 EGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAIL 465
G+ LD +V KY + + GV+ ++ Q + E+ + LR+ ++L
Sbjct: 715 -GVAYYDLDA-KRKVSKYSLIFFTAGVITLASNIFQHYIYGVVGEKAMKILREAIFSSVL 772
Query: 466 RQQIQWFDKQQTGN--LTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSM 639
R ++ WF+K + G LT+R+ D V+ + D+ A++VQ ++ L V + +W M
Sbjct: 773 RNELGWFEKPKNGVGFLTSRIVSDTSTVKTIISDRMAVIVQCISSILIATVVSMYVNWRM 832
Query: 640 TLVMMGFAPLIVLSG---AKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHK 810
LV P + G AK +K + + + ++A E S+IRTV S
Sbjct: 833 GLVSWAVMPCHFIGGLIQAKAAKGFYGDSAIAHQELV---SLASEAASNIRTVASFVYED 889
Query: 811 RELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYS-SYALAFWYGSTLIIN-DPTFDR 984
+ + +L+ + ++ G+ G S LC+++ ++A+A WY + L+ +F+
Sbjct: 890 EIIKKAELSLQEPMRVTKIESMKYGVVQGIS-LCLWNIAHAVALWYTTVLVQRKQASFEN 948
Query: 985 GL-IFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDN 1161
+ + +F + T L +P + S A + +++ +I P E
Sbjct: 949 SIRSYQIFSLTVPSITELWTLIPMVMS---AIAVLNPAFEMLDRDTQIVPDRPENPSDGW 1005
Query: 1162 MKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPT 1341
+ G F+DV F YPSR ++ +L G SL ++ G ++ALVG SG GKS+++ LL RFYDP
Sbjct: 1006 LMGRTEFQDVSFNYPSRPEVTILDGFSLVIEPGQRVALVGPSGAGKSSVLALLLRFYDPQ 1065
Query: 1342 KGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMA 1521
+GRVLID ++++ N+ LR+QIG+V QEP+LF+ +I +NI G+E + ++++A A
Sbjct: 1066 RGRVLIDNKNIKDYNLRWLRKQIGLVQQEPILFNSSIRDNISYGSEETSETEIIQAAMEA 1125
Query: 1522 NANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAER 1701
N ++FI LP GY T VGEKG QLSGGQKQRIAIAR L+K P ILLLDEATSALD E+ER
Sbjct: 1126 NIHEFISSLPKGYDTVVGEKGSQLSGGQKQRIAIARTLLKRPVILLLDEATSALDGESER 1185
Query: 1702 EVQGAL--------DQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMS 1851
V +L ++ + T+I VAHRLST+ N D I V + G +VE G+H L++
Sbjct: 1186 VVMSSLGAKDWKDRNEGSSKITSITVAHRLSTVINSDTIVVMERGKVVELGNHHTLIT 1243
>gi|730011|sp|Q06034|MDR1_LEIEN Multidrug resistance protein 1
(P-glycoprotein 1)
gi|159370|gb|AAA16255.1| multidrug resistance protein
Length = 1280
Score = 662 bits (1708), Expect = 0.0
Identities = 423/1235 (34%), Positives = 643/1235 (51%), Gaps = 26/1235 (2%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
IF Y D +L+I GT AV GAG P+ + + G + D + GV +
Sbjct: 60 IFRYADATDRVLMIAGTAFAVACGAGMPVFSFIFGRIAM--------DLMSGVGSAE--- 108
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
+ K + + +G+ M + C+ A R V ++R + +A+LRQ
Sbjct: 109 ----------EKAAKTSLIMVYVGIAMLIACAGHVMCWTVAACRQVARIRLLFFRAVLRQ 158
Query: 472 QIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVM 651
I W D+ G LTAR+T D ++ G+ DK + + + + GY GF +SW +TL+M
Sbjct: 159 DIGWHDEHSPGALTARMTGDTRVIQNGINDKLSQGIMNGSMGVIGYIAGFVFSWELTLMM 218
Query: 652 MGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFY 831
+G P I++ A + ++ T ++ +A AG++A E +IRTV + EL+RF
Sbjct: 219 IGMMPFIIVMAAIIGSIVSKITESSRKYFAKAGSLATEVMENIRTVQAFGREDYELERFT 278
Query: 832 NALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFA 1011
A+ + GI K + MY SY +AF++GS L+ D I + F A
Sbjct: 279 KAVLYAQGRGIRKELASNLSAAVIMALMYVSYTVAFFFGSYLV-EWGRRDMADIISTFLA 337
Query: 1012 VLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDV 1191
VL GS LG P +F +R AA + + I+ P +D G+ V K I F++V
Sbjct: 338 VLMGSFGLGFVAPSRTAFTESRAAAYEIFKAIDRVPPVD-IDAGGVPVPGFKESIEFRNV 396
Query: 1192 HFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVD 1371
F YP+R + + + +SL++K G K+A G+SGCGKS+++ L+QRFYDP G VL+DGV
Sbjct: 397 RFAYPTRPGMILFRDLSLKIKCGQKVAFSGASGCGKSSVIGLIQRFYDPIGGAVLVDGVR 456
Query: 1372 LREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLP 1551
+RE+ + R+QIGIVSQEP LF GT+ EN++MG +AT ++VVEAC+ AN +D I LP
Sbjct: 457 MRELCLREWRDQIGIVSQEPNLFAGTMMENVRMGKPNATDEEVVEACRQANIHDTIMALP 516
Query: 1552 DGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQ-- 1725
D Y T VG G LSGGQKQRIAIARALVK P ILLLDEATSALD ++E EVQ ALDQ
Sbjct: 517 DRYDTPVGPVGSLLSGGQKQRIAIARALVKRPPILLLDEATSALDRKSEMEVQAALDQLI 576
Query: 1726 AQAGRTTIIVAHRLSTIRNVDRIFVFK-----AGNIVESGSHEELMSKQGIFYDMTXXXX 1890
+ G T +++AHRL+TIR++DRI+ K I ESG+ +EL+ G F +
Sbjct: 577 QRGGTTVVVIAHRLATIRDMDRIYYVKHDGAEGSRITESGTFDELLELDGEFAAVAKMQG 636
Query: 1891 XXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEE--------VEECKA 2046
++G + D ++ A HL + + A + E K
Sbjct: 637 VLAGDAKSGASVRD--AKKASGHLGVILDEADLAQLDEDVPRTARQNVPIDELAKWEVKH 694
Query: 2047 PPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNV---YSLPAD--QMQ 2211
++ + N DK S P ++V + V YS D ++
Sbjct: 695 AKVGFLRLMRMNKDKAWAVALGILSSVVIGSARPASSIVMGHMLRVLGEYSATKDVEALR 754
Query: 2212 ANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRH 2391
+ + +F++ + F G+ G GE LT K+R F+ ++RQDI F+D
Sbjct: 755 SGTNLYAPLFIVFAVANFSGWILH-GFYGYAGEHLTTKIRVLLFRQIMRQDINFFDIPGR 813
Query: 2392 GTGKLCTRFATDAPNVRYVFTRLPVVLASIVTIC---GALGIGFYYGWQXXXXXXXXXXX 2562
G L + D V ++ P + + T+C L +GF Y W+
Sbjct: 814 DAGTLAGMLSGDCEAVHQLWG--PSIGLKVQTMCIIASGLVVGFIYQWK-LALVALACMP 870
Query: 2563 XXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREP 2742
+G ++ + + + + ++A+ ++RTV SLN +E + LRE
Sbjct: 871 LMIGCSLTRRLMINGYTKSRE-GDTDDTIVTEALSNVRTVTSLNMKEDCVEAFQAALREE 929
Query: 2743 FNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQM 2922
+++ G ++ +Q + + +YA F+ GS +++ + DV +I F Q
Sbjct: 930 APRSVRKGIIAGGIYGITQFIFYGVYALCFWYGSKLIDKGEAEFKDVMIASMSILFGAQN 989
Query: 2923 IGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITG-NISIRNVFFNYPTR 3099
G +F + A +A +F +I+ +D + +G G +I RNV F Y R
Sbjct: 990 AGEAGAFATKLADAEASAKRVFSVIDRVPDVD-IEQAGNKDLGEGCDIEYRNVQFIYSAR 1048
Query: 3100 KDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNIS 3279
VL + + L+G +GCGKST++ +L RFY + G+I ++G ++ +L+I+
Sbjct: 1049 PKQVVLASVNMRFGDATSNGLIGQTGCGKSTVIQMLARFYERRSGLISVNGRDLSSLDIA 1108
Query: 3280 SLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTH 3459
R + IV QEP LF T+ ENI Y T +E+ EAA++A+IH+ I+ DGYDT
Sbjct: 1109 EWRRNISIVLQEPNLFSGTVRENIRY-AREGATDEEVEEAARLAHIHHEIIKWTDGYDTE 1167
Query: 3460 VGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDA--AKQGRT 3633
VG KG LSGGQKQRIAIAR L+R P +LLLDEATSALD+ +E VQE ++A AK T
Sbjct: 1168 VGYKGRALSGGQKQRIAIARGLLRRPRLLLLDEATSALDSVTEAKVQEGIEAFQAKYKVT 1227
Query: 3634 CLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELI 3738
+ IAHRL+TI++ D I ++ G I+E+G+H+EL+
Sbjct: 1228 TVSIAHRLTTIRHCDQIILLDSGCIIEQGSHEELM 1262
Score = 288 bits (738), Expect = 5e-76
Identities = 194/581 (33%), Positives = 292/581 (49%), Gaps = 8/581 (1%)
Frame = +1
Query: 157 GTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEVVK 336
G +++V+ G+ P +IV+G M V E ++ S
Sbjct: 716 GILSSVVIGSARPASSIVMGHMLRVL----------------GEYSATKDVEALRSGTNL 759
Query: 337 YCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD--KQQTGNL 510
Y ++V V F + ++ + E L K+R + I+RQ I +FD + G L
Sbjct: 760 YAPLFIVFAVANF-SGWILHGFYGYAGEHLTTKIRVLLFRQIMRQDINFFDIPGRDAGTL 818
Query: 511 TARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAK 690
L+ D E V + G L VQ +G VGF Y W + LV + PL++ G
Sbjct: 819 AGMLSGDCEAVHQLWGPSIGLKVQTMCIIASGLVVGFIYQWKLALVALACMPLMI--GCS 876
Query: 691 MSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVK 870
+++ + + I E S++RTV SLN + ++ F AL + K
Sbjct: 877 LTRRLMINGYTKSREGDTDDTIVTEALSNVRTVTSLNMKEDCVEAFQAALREEAPRSVRK 936
Query: 871 YCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALP 1050
G G + Y YAL FWYGS LI + ++ ++L G+ + G A
Sbjct: 937 GIIAGGIYGITQFIFYGVYALCFWYGSKLIDKGEAEFKDVMIASM-SILFGAQNAGEAGA 995
Query: 1051 HLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKG-DISFKDVHFRYPSRKDIHV 1227
A +A V VI+ P +D D +G DI +++V F Y +R V
Sbjct: 996 FATKLADAEASAKRVFSVIDRVPDVDIEQAGN--KDLGEGCDIEYRNVQFIYSARPKQVV 1053
Query: 1228 LKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQ 1407
L +++ L+G +GCGKST++ +L RFY+ G + ++G DL +++ R
Sbjct: 1054 LASVNMRFGDATSNGLIGQTGCGKSTVIQMLARFYERRSGLISVNGRDLSSLDIAEWRRN 1113
Query: 1408 IGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGV 1587
I IV QEP LF GT+ ENI+ E AT ++V EA ++A+ + I + DGY T VG KG
Sbjct: 1114 ISIVLQEPNLFSGTVRENIRYAREGATDEEVEEAARLAHIHHEIIKWTDGYDTEVGYKGR 1173
Query: 1588 QLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALD--QAQAGRTTIIVAH 1761
LSGGQKQRIAIAR L++ P++LLLDEATSALD+ E +VQ ++ QA+ TT+ +AH
Sbjct: 1174 ALSGGQKQRIAIARGLLRRPRLLLLDEATSALDSVTEAKVQEGIEAFQAKYKVTTVSIAH 1233
Query: 1762 RLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIF---YDM 1875
RL+TIR+ D+I + +G I+E GSHEELM+ G + YD+
Sbjct: 1234 RLTTIRHCDQIILLDSGCIIEQGSHEELMALGGEYKTRYDL 1274
>gi|4521245|dbj|BAA76299.1| LAMDR1 [Leishmania mexicana amazonensis]
Length = 1341
Score = 654 bits (1688), Expect = 0.0
Identities = 423/1234 (34%), Positives = 641/1234 (51%), Gaps = 25/1234 (2%)
Frame = +1
Query: 112 IFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEG 291
IF Y D +L+I GT+ AV GAG PL + + G + T D + GV +V
Sbjct: 121 IFRYADTADRVLMIIGTIFAVCSGAGMPLFSFIFGRIAT--------DLMSGVGSV---- 168
Query: 292 LVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQ 471
E N+ + Y+ +G MF + C+ A R ++R N+ +A+LRQ
Sbjct: 169 -------ELNAAKTSLIMVYVGIG--MFVACGGHVLCWTVAASRQEGRIRLNFFRAVLRQ 219
Query: 472 QIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVM 651
I W D+ G LTAR+T D + G+ DK + + A + GY GF +SW +TLVM
Sbjct: 220 DIGWHDEHSPGELTARMTGDTRVIHNGINDKLSQGIMNGAMGIIGYIAGFVFSWELTLVM 279
Query: 652 MGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFY 831
+G P I++ A + ++ T ++ +A AG++A E +IRTV EL RF
Sbjct: 280 VGMMPFIIVMAAIIGNIVSKMTESSRKHFAKAGSMATEVMENIRTVQVFGREDYELQRFA 339
Query: 832 NALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFA 1011
A+ ++ GI K + +Y SY +AF++GS L+ D I + F A
Sbjct: 340 EAVLYAQERGIHKEFAGSLSAAVVMALVYLSYTVAFFFGSYLV-EWGRRDMADIISTFLA 398
Query: 1012 VLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDV 1191
VL GS LG P +F +R AA + + I P +D G+ V + I F +V
Sbjct: 399 VLMGSFGLGFVAPSATAFTESRAAAYEIFKTIERVPPVD-IDAGGVPVTGFRQSIEFHNV 457
Query: 1192 HFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVD 1371
F YP+R D+ + + ++L +K G K+A GSSGCGKS+++ L+QRFYDP G VL DGVD
Sbjct: 458 RFSYPTRPDMILFRDLNLTIKRGQKVAFSGSSGCGKSSMIGLIQRFYDPVGGAVLCDGVD 517
Query: 1372 LREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLP 1551
+RE+ ++ R+QIGIVSQEP LF GT+ EN+++G +AT ++V+EAC+ AN +D I LP
Sbjct: 518 MRELCLYDWRDQIGIVSQEPNLFAGTMMENVRVGKPNATEEEVIEACRQANVHDTIMSLP 577
Query: 1552 DGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQ-- 1725
D Y T VG G QLSGGQKQRIAIARALVK P ILLLDEATSALD ++E EVQ +LDQ
Sbjct: 578 DQYNTPVGAVGSQLSGGQKQRIAIARALVKRPPILLLDEATSALDRKSEMEVQRSLDQLM 637
Query: 1726 AQAGRTTIIVAHRLSTIRNVDRIFVFK-----AGNIVESGSHEELMSKQGIFYDMTXXXX 1890
+ G T I++AHRL TIRNVD I+ K I ESG+ +ELM+ G F M
Sbjct: 638 QKGGMTVIVIAHRLETIRNVDCIYYMKYDGEEGSKITESGTFDELMALGGEFAAMARIQG 697
Query: 1891 XXXXXXEAG---------KDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECK 2043
+G D+ + I + A + I +LA+ E
Sbjct: 698 VSAGNARSGAKGQDDSKANDLLNVILDEA-TLAQLDEEAPRTARQKVPIEELAK--WEVN 754
Query: 2044 APPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNV-----YSLPADQM 2208
++ N DK+ + P +++ + V ++ +Q+
Sbjct: 755 GVNVGFGRLMGMNKDKLWAVALGILGSAVGGAARPTSSILMGYMLRVLGEYSFNKNVEQL 814
Query: 2209 QANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLR 2388
++ + +F++ + F+G+ G GE LT K+R F+ ++RQD+ F+D
Sbjct: 815 RSGTNLYAPLFIVFAVGNFLGWVLH-GFYGYAGEHLTTKIRLLLFRQIMRQDMNFFDIPG 873
Query: 2389 HGTGKLCTRFATDAPNVRYVF-TRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXX 2565
G L + D V ++ + + + + I + + F Y W+
Sbjct: 874 RDAGSLAGMLSGDCEAVHQLWGPSIGLKVQMVCIIAAGVVVSFIYQWKLALVALACMPLL 933
Query: 2566 XMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPF 2745
E M + ++ + + + ++A+ +RTV S N + + LR
Sbjct: 934 IGCSLAERMMM--NRYTKSKDGDTSDTIVTEALSSVRTVTSFNMKADRVEAFEATLRVET 991
Query: 2746 NTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMI 2925
+K G++ Q + + +A F+ GS +++ Q DV +I F Q
Sbjct: 992 PHGVKKGIIAGSINGARQFIHYGAFALCFWYGSKLIDRGEAQFTDVMIASMSILFGAQST 1051
Query: 2926 GNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITG-NISIRNVFFNYPTRK 3102
G+ +F + +A +A +F +I+ +D + SG G ++ R V F Y R
Sbjct: 1052 GDAGAFATKLAEAERSAKRVFSVIDRVPDLD-IEQSGDKDLGKGCDVDFRKVQFIYSARP 1110
Query: 3103 DTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISS 3282
VL L G T L+G +GCGKSTI+ +L RFY++ G+I ++G ++ +L+I+
Sbjct: 1111 KQAVLASVNLRFGDGTTNGLIGQTGCGKSTIIQMLARFYDRRSGLICVNGKDLSSLDIAE 1170
Query: 3283 LREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHV 3462
R + +V QEP LF T+ ENI Y + T +E+ EAA++A+IH I+ P GY+T V
Sbjct: 1171 WRRNISVVLQEPDLFSGTVRENIRY-AREDATDEEVEEAARLAHIHQEIMKWPGGYNTEV 1229
Query: 3463 GEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDA--AKQGRTC 3636
G KG+ LSGGQKQR+AIAR L+R P +LLLDEATSALD +E VQ+ ++A AK G T
Sbjct: 1230 GYKGSALSGGQKQRVAIARGLLRRPKLLLLDEATSALDNVTEAKVQDGINAYQAKYGVTS 1289
Query: 3637 LVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELI 3738
+ IAHRL+TI++ D I ++ G I+E+G+H+EL+
Sbjct: 1290 VSIAHRLTTIRHCDQIILLDAGHIIEQGSHEELM 1323
Score = 306 bits (783), Expect = 3e-81
Identities = 203/578 (35%), Positives = 294/578 (50%), Gaps = 10/578 (1%)
Frame = +1
Query: 157 GTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEVVK 336
G + + + GA P +I++G M V +G + N ++++ S
Sbjct: 777 GILGSAVGGAARPTSSILMGYMLRV----------LGEYSFNK------NVEQLRSGTNL 820
Query: 337 YCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD--KQQTGNL 510
Y ++V V F +V + E L K+R + I+RQ + +FD + G+L
Sbjct: 821 YAPLFIVFAVGNFL-GWVLHGFYGYAGEHLTTKIRLLLFRQIMRQDMNFFDIPGRDAGSL 879
Query: 511 TARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAK 690
L+ D E V + G L VQM AG V F Y W + LV + PL++ G
Sbjct: 880 AGMLSGDCEAVHQLWGPSIGLKVQMVCIIAAGVVVSFIYQWKLALVALACMPLLI--GCS 937
Query: 691 MSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVK 870
+++ M + + + I E SS+RTV S N ++ F L V G+ K
Sbjct: 938 LAERMMMNRYTKSKDGDTSDTIVTEALSSVRTVTSFNMKADRVEAFEATLRVETPHGVKK 997
Query: 871 YCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGL-----IFTVFFAVLSGSTSL 1035
G G Y ++AL FWYGS LI DRG + ++L G+ S
Sbjct: 998 GIIAGSINGARQFIHYGAFALCFWYGSKLI------DRGEAQFTDVMIASMSILFGAQST 1051
Query: 1036 GGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKG-DISFKDVHFRYPSR 1212
G A A +A V VI+ P +D D KG D+ F+ V F Y +R
Sbjct: 1052 GDAGAFATKLAEAERSAKRVFSVIDRVPDLDIEQSGD--KDLGKGCDVDFRKVQFIYSAR 1109
Query: 1213 KDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVH 1392
VL ++L G L+G +GCGKSTI+ +L RFYD G + ++G DL +++
Sbjct: 1110 PKQAVLASVNLRFGDGTTNGLIGQTGCGKSTIIQMLARFYDRRSGLICVNGKDLSSLDIA 1169
Query: 1393 SLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRV 1572
R I +V QEP LF GT+ ENI+ E AT ++V EA ++A+ + I + P GY T V
Sbjct: 1170 EWRRNISVVLQEPDLFSGTVRENIRYAREDATDEEVEEAARLAHIHQEIMKWPGGYNTEV 1229
Query: 1573 GEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALD--QAQAGRTT 1746
G KG LSGGQKQR+AIAR L++ PK+LLLDEATSALD E +VQ ++ QA+ G T+
Sbjct: 1230 GYKGSALSGGQKQRVAIARGLLRRPKLLLLDEATSALDNVTEAKVQDGINAYQAKYGVTS 1289
Query: 1747 IIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQG 1860
+ +AHRL+TIR+ D+I + AG+I+E GSHEELM+ G
Sbjct: 1290 VSIAHRLTTIRHCDQIILLDAGHIIEQGSHEELMALGG 1327
>gi|27368869|emb|CAD59592.1| MDR-like ABC transporter [Oryza sativa
(japonica cultivar-group)]
Length = 1279
Score = 654 bits (1687), Expect = 0.0
Identities = 408/1182 (34%), Positives = 625/1182 (52%), Gaps = 69/1182 (5%)
Frame = +1
Query: 400 CFESYAERLVHKLRQNYLKAILRQQIQWFD-------------KQQTGNLTARLTDDLER 540
C+ AER K+R+ YL+A+L Q++ +FD + T + + ++DD +
Sbjct: 75 CWTRTAERQASKMRRLYLEAVLSQEVAFFDAAPSSPSSPQAQAQATTFRVISTVSDDADA 134
Query: 541 VREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLI-VLSGAKMSKSMATRT 717
+++ LG+K +++ F V F ++W + L + F L+ V ++ MA
Sbjct: 135 IQDFLGEKLPMVLANATLFFGALAVSFVFAWRLALAGLPFTLLLFVTPSVLLAGRMAAAA 194
Query: 718 RVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVG 897
+ Y AG IA++ SSIRTV S +R ++RF A+ G+ + G +G
Sbjct: 195 GEARAAYEEAGGIAQQAVSSIRTVASYTAERRTVERFRGAVARSAALGVRQGLIKGAVIG 254
Query: 898 FSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTAR 1077
+ +Y+ ++ W GS L+I+ G +F ++ S+ ALP+L F A
Sbjct: 255 SMGV-IYAVWSFLSWIGSLLVIHLHA-QGGHVFVASICIVLAGMSIMMALPNLRYFIDAT 312
Query: 1078 GAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKA 1257
AAS + +I P ++ +G ++ ++G+I FKDVHF YPSR D VL G +L +
Sbjct: 313 AAASRMQEMIEMLPPLEGAEKKGATMERIRGEIVFKDVHFSYPSRPDTLVLNGFNLTISE 372
Query: 1258 GDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVL 1437
G + LVG SG GKST+++LLQRFY P G + +D + +NV LR QIG+VSQEPVL
Sbjct: 373 GATVGLVGGSGSGKSTVISLLQRFYSPDSGEISMDDHGIDTLNVEWLRSQIGLVSQEPVL 432
Query: 1438 FDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGT----------------- 1566
F +I ENI G+E A+ QVV A KMANA++FI +LP GY T
Sbjct: 433 FATSIRENILFGDETASLKQVVAAAKMANAHEFIVKLPHGYETHVHKQQQFLQCMLQHAE 492
Query: 1567 ----------RVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGA 1716
+VG+ G QLSGGQKQRIAIARALV++P+ILLLDEATSALD E+ER VQ A
Sbjct: 493 SYGVFFFSPVQVGQFGTQLSGGQKQRIAIARALVRDPRILLLDEATSALDAESERTVQDA 552
Query: 1717 LDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELM-----SKQGIFYDMTX 1881
LD+A GRTT+IVAHRLST+R D I V AG +VE+G+H+EL+ + G++ M
Sbjct: 553 LDRASVGRTTVIVAHRLSTLRKADTIAVLDAGRVVEAGTHDELLGMDDGGEGGVYARMVH 612
Query: 1882 XXXXXXXXXE---------------AGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQ 2016
+ + +E + SA H I +
Sbjct: 613 LQKAPPVAAREERHRAVDVVESEMVSFRSVEIMSAVSATEHRPSPAPSFCSVEHSTEIGR 672
Query: 2017 LAEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVYSLP 2196
+ ++ S ++ K N + +V P+++ + VY L
Sbjct: 673 KLVDHGVARSRKPSKLRLLKMNRPEWKQALLGCVGAVVFGAVLPLYSYSLGSLPEVYFLA 732
Query: 2197 AD-QMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAF 2373
D Q+++ + +F+ + + GE LT ++R + +L ++ +
Sbjct: 733 DDGQIRSKTRLYYFLFLGIAVVCITANIVQHYNFAVMGERLTERVRGQMLAKILSFEVGW 792
Query: 2374 YDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXX 2550
+D+ + + +C R AT + VR V R+ +++ + T + W+
Sbjct: 793 FDEDENSSAAVCARLATQSSKVRSLVGDRMCLLVQAGATASLGFSLALAVSWRLATVMMA 852
Query: 2551 XXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEY 2730
YF+ + + + + ++AS+AV + RT+ + + Q + Y
Sbjct: 853 MQPLIIASFYFKKVLMAAMSKKAKKAQVQGSQLASEAVVNHRTITAFSSQRRMLRLYEAA 912
Query: 2731 LREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISF 2910
+ P N+ H+ G Q A A + G + + + P +++VFF +
Sbjct: 913 QQGPKKDNVAHSWFSGFCLCLCQFSNTGSMAVALWYGGKLMAKGLITPTHLFQVFFMLMT 972
Query: 2911 CGQMIGNTTSFIPDVVKARLAA-SLLFYLIEHPTPIDSLSDSGIV----KPITGNISIRN 3075
G++I + S D+ + A S+L L PT D +D+ K I G I +N
Sbjct: 973 MGRVIADAGSLTSDLAQGGDAVRSVLDTLDREPTIKDDDNDNERKKKKRKEIKGAIEFKN 1032
Query: 3076 VFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGD 3255
V F+YPTR + VL GF+L+I AGKTVALVG SG GKST++GL+ERFY+ +G +++DG+
Sbjct: 1033 VHFSYPTRPEVAVLAGFSLEIGAGKTVALVGPSGSGKSTVIGLIERFYDAQRGSVLVDGE 1092
Query: 3256 NIRNLNISSLREQVCIVSQEPTLFDCTIGENICYG-TNRNVTYQEIVEAAKMANIHNFIL 3432
+IR+ +++ LR QV +VSQEPTLF TI +NI YG + T E+ AA +AN H FI
Sbjct: 1093 DIRSYSLARLRSQVALVSQEPTLFSGTIRDNIAYGAAEEHATEDEVARAAALANAHGFIS 1152
Query: 3433 GLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALD 3612
+ GYDT VGE+G QLSGGQ+QRIA+ARA+++ +LLLDEATSALD SE++VQ+A+D
Sbjct: 1153 AMERGYDTRVGERGAQLSGGQRQRIALARAVLKDARILLLDEATSALDAASERLVQDAVD 1212
Query: 3613 AAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELI 3738
+GRTC+V+AHRLST++ SD IA+V +G++ E+G H EL+
Sbjct: 1213 RMLRGRTCVVVAHRLSTVEKSDTIAVVKDGRVAERGRHHELL 1254
Score = 347 bits (890), Expect = 1e-93
Identities = 219/592 (36%), Positives = 316/592 (52%), Gaps = 17/592 (2%)
Frame = +1
Query: 151 ITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEV 330
+ G V AV+ GA PL + LG + V+ A + + S+
Sbjct: 702 LLGCVGAVVFGAVLPLYSYSLGSLPEVYFLADDG--------------------QIRSKT 741
Query: 331 VKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGN- 507
Y +L + V+ + VQ F ERL ++R L IL ++ WFD+ + +
Sbjct: 742 RLYYFLFLGIAVVCITANIVQHYNFAVMGERLTERVRGQMLAKILSFEVGWFDEDENSSA 801
Query: 508 -LTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSG 684
+ ARL +VR +GD+ LLVQ A G+ + SW + VMM PLI+ S
Sbjct: 802 AVCARLATQSSKVRSLVGDRMCLLVQAGATASLGFSLALAVSWRLATVMMAMQPLIIASF 861
Query: 685 AKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGI 864
MA ++ ++ +A E + RT+ + + +R L R Y A + G +
Sbjct: 862 YFKKVLMAAMSKKAKKAQVQGSQLASEAVVNHRTITAFSSQRRML-RLYEAAQQGPKKDN 920
Query: 865 VKYCYMGIGVGFSN-LCMYS---SYALAFWYGSTLIIND---PTFDRGLIFTVFFAVLSG 1023
V + + GF LC +S S A+A WYG L+ PT +F VFF +++
Sbjct: 921 VAHSWFS---GFCLCLCQFSNTGSMAVALWYGGKLMAKGLITPTH----LFQVFFMLMTM 973
Query: 1024 STSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDN----MKGDISFKDV 1191
+ A + A +VL ++ P I + +KG I FK+V
Sbjct: 974 GRVIADAGSLTSDLAQGGDAVRSVLDTLDREPTIKDDDNDNERKKKKRKEIKGAIEFKNV 1033
Query: 1192 HFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVD 1371
HF YP+R ++ VL G SLE+ AG +ALVG SG GKST++ L++RFYD +G VL+DG D
Sbjct: 1034 HFSYPTRPEVAVLAGFSLEIGAGKTVALVGPSGSGKSTVIGLIERFYDAQRGSVLVDGED 1093
Query: 1372 LREVNVHSLREQIGIVSQEPVLFDGTIYENIKMG--NEHATHDQVVEACKMANANDFIKR 1545
+R ++ LR Q+ +VSQEP LF GTI +NI G EHAT D+V A +ANA+ FI
Sbjct: 1094 IRSYSLARLRSQVALVSQEPTLFSGTIRDNIAYGAAEEHATEDEVARAAALANAHGFISA 1153
Query: 1546 LPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQ 1725
+ GY TRVGE+G QLSGGQ+QRIA+ARA++K+ +ILLLDEATSALD +ER VQ A+D+
Sbjct: 1154 MERGYDTRVGERGAQLSGGQRQRIALARAVLKDARILLLDEATSALDAASERLVQDAVDR 1213
Query: 1726 AQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMS--KQGIFYDM 1875
GRT ++VAHRLST+ D I V K G + E G H EL++ + G +Y++
Sbjct: 1214 MLRGRTCVVVAHRLSTVEKSDTIAVVKDGRVAERGRHHELLAVGRAGTYYNL 1265
Score = 299 bits (766), Expect = 3e-79
Identities = 195/534 (36%), Positives = 280/534 (51%), Gaps = 41/534 (7%)
Frame = +1
Query: 2260 FFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYD-----------DLRHGTGKL 2406
F G C R E K+R + +L Q++AF+D + T ++
Sbjct: 65 FSSGAVDKGLCWTRTAERQASKMRRLYLEAVLSQEVAFFDAAPSSPSSPQAQAQATTFRV 124
Query: 2407 CTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYF 2583
+ + DA ++ ++ +LP+VLA+ GAL + F + W+ +
Sbjct: 125 ISTVSDDADAIQDFLGEKLPMVLANATLFFGALAVSFVFAWRLALAGLPFTLLLFVTPSV 184
Query: 2584 EMQMRFGKQIRDTQLL-EEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLK 2760
+ R + + EEAG +A QAV IRTV S + + + + ++
Sbjct: 185 LLAGRMAAAAGEARAAYEEAGGIAQQAVSSIRTVASYTAERRTVERFRGAVARSAALGVR 244
Query: 2761 HAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTS 2940
GAV S +I+ +++ ++GS+ V Q V+ I G I
Sbjct: 245 QGLIKGAVIG-SMGVIYAVWSFLSWIGSLLVIHLHAQGGHVFVASICIVLAGMSIMMALP 303
Query: 2941 FIPDVVKARLAASLLFYLIEHPTPIDSLSDSGI-VKPITGNISIRNVFFNYPTRKDTKVL 3117
+ + A AAS + +IE P++ G ++ I G I ++V F+YP+R DT VL
Sbjct: 304 NLRYFIDATAAASRMQEMIEMLPPLEGAEKKGATMERIRGEIVFKDVHFSYPSRPDTLVL 363
Query: 3118 QGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQV 3297
GF L I G TV LVG SG GKST++ LL+RFY+ D G I +D I LN+ LR Q+
Sbjct: 364 NGFNLTISEGATVGLVGGSGSGKSTVISLLQRFYSPDSGEISMDDHGIDTLNVEWLRSQI 423
Query: 3298 CIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHV----- 3462
+VSQEP LF +I ENI +G + + +++V AAKMAN H FI+ LP GY+THV
Sbjct: 424 GLVSQEPVLFATSIRENILFG-DETASLKQVVAAAKMANAHEFIVKLPHGYETHVHKQQQ 482
Query: 3463 ----------------------GEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALD 3576
G+ GTQLSGGQKQRIAIARALVR P +LLLDEATSALD
Sbjct: 483 FLQCMLQHAESYGVFFFSPVQVGQFGTQLSGGQKQRIAIARALVRDPRILLLDEATSALD 542
Query: 3577 TESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELI 3738
ESE+ VQ+ALD A GRT +++AHRLST++ +D IA++ G++VE GTHDEL+
Sbjct: 543 AESERTVQDALDRASVGRTTVIVAHRLSTLRKADTIAVLDAGRVVEAGTHDELL 596
>gi|33307712|gb|AAQ03033.1| P-glycoprotein [Homo sapiens]
Length = 832
Score = 652 bits (1681), Expect = 0.0
Identities = 366/834 (43%), Positives = 506/834 (59%), Gaps = 6/834 (0%)
Frame = +1
Query: 1300 STIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNE 1479
ST+V LLQR YDP G +++D D+R +NV R+ IG+VSQEPVLF TI NIK G +
Sbjct: 3 STVVQLLQRLYDPDDGFIMVDENDIRALNVRHYRDHIGVVSQEPVLFGTTISNNIKYGRD 62
Query: 1480 HATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILL 1659
T +++ A + ANA DFI P+ + T VGEKG Q+SGGQKQRIAIARALV+NPKIL+
Sbjct: 63 DVTDEEMERAAREANAYDFIMEFPNKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILI 122
Query: 1660 LDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHE 1839
LDEATSALD+E++ VQ AL++A GRTTI+VAHRLSTIR+ D I K G + E G+H
Sbjct: 123 LDEATSALDSESKSAVQAALEKASKGRTTIVVAHRLSTIRSADLIVTLKDGMLAEKGAHA 182
Query: 1840 ELMSKQGIFYDMTXXXXXXXXXXEAGKDIED-TISESAHSHLXXXXXXXXXXXXXXXIHQ 2016
ELM+K+G++Y + +A + +E T S ++ +
Sbjct: 183 ELMAKRGLYYSLV----MSQDIKKADEQMESMTYSTERKTNSLPLHSVKSIKSDFIDKAE 238
Query: 2017 LAEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNVY-SL 2193
+ + +E P S+ KI K N + + +V PVF++++A+I ++ +
Sbjct: 239 ESTQSKEISLPEVSLLKILKLNKPEWPFVVLGTLASVLNGTVHPVFSIIFAKIITMFGNN 298
Query: 2194 PADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAF 2373
++ + + +FV++G+ FV +F GR GE LTM+LR AFK +L QDIA+
Sbjct: 299 DKTTLKHDAEIYSMIFVILGVICFVSYFMQGLFYGRAGEILTMRLRHLAFKAMLYQDIAW 358
Query: 2374 YDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFYYGWQXXXXXXX 2550
+D+ + TG L T A D ++ +R+ V+ + + ++ I F YGW+
Sbjct: 359 FDEKENSTGGLTTILAIDIAQIQGATGSRIGVLTQNATNMGLSVIISFIYGWEMTFLILS 418
Query: 2551 XXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEY 2730
+ G E G +D Q L+ AGK+A++A+E+IRT+ SL R++ F Y E
Sbjct: 419 IAPVLAVTGMIETAAMTGFANKDKQELKHAGKIATEALENIRTIVSLTREKAFEQMYEEM 478
Query: 2731 LREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISF 2910
L+ K A G+ +AFS + I+F YAA F G+ + M P ++ VF AI++
Sbjct: 479 LQTQHRNTSKKAQIIGSCYAFSHAFIYFAYAAGFRFGAYLIQAGRMTPEGMFIVFTAIAY 538
Query: 2911 CGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPIT--GNISIRNVFF 3084
IG T P+ KA+ A+ LF L+E IDS S G KP T GN+ R V F
Sbjct: 539 GAMAIGKTLVLAPEYSKAKSGAAHLFALLEKKPNIDSRSQEG-KKPDTCEGNLEFREVSF 597
Query: 3085 NYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIR 3264
YP R D +L+G +L I+ GKTVA VG SGCGKST + LL+R Y+ +G ++ DG + +
Sbjct: 598 FYPCRPDVFILRGLSLSIERGKTVAFVGSSGCGKSTSVQLLQRLYDPVQGQVLFDGVDAK 657
Query: 3265 NLNISSLREQVCIVSQEPTLFDCTIGENICYGTN-RNVTYQEIVEAAKMANIHNFILGLP 3441
LN+ LR Q+ IV QEP LF+C+I ENI YG N R V EI EAA ANIH+FI GLP
Sbjct: 658 ELNVQWLRSQIAIVPQEPVLFNCSIAENIAYGDNSRVVPLDEIKEAANAANIHSFIEGLP 717
Query: 3442 DGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDAAK 3621
+ Y+T VG KG QLSGGQKQR+AIARAL++ P +LLLDEATSALD +SEK+VQ ALD A+
Sbjct: 718 EKYNTQVGLKGAQLSGGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDKAR 777
Query: 3622 QGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCETQRI 3783
GRTCLV+ HRLS IQN+D+I ++ GKI E+GTH EL+R +IY K Q +
Sbjct: 778 TGRTCLVVTHRLSAIQNADLIVVLHNGKIKEQGTHQELLRNRDIYFKLVNAQSV 831
Score = 377 bits (969), Expect = e-103
Identities = 217/580 (37%), Positives = 331/580 (56%), Gaps = 4/580 (0%)
Frame = +1
Query: 148 LITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSE 327
++ GT+A+V++G P+ +I+ + T+F + + ++E
Sbjct: 267 VVLGTLASVLNGTVHPVFSIIFAKIITMFGNNDKTTL------------------KHDAE 308
Query: 328 VVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQ--T 501
+ Y + +++LGV+ F + ++Q + E L +LR KA+L Q I WFD+++ T
Sbjct: 309 I--YSMIFVILGVICFVSYFMQGLFYGRAGEILTMRLRHLAFKAMLYQDIAWFDEKENST 366
Query: 502 GNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLS 681
G LT L D+ +++ G + +L Q + F Y W MT +++ AP++ ++
Sbjct: 367 GGLTTILAIDIAQIQGATGSRIGVLTQNATNMGLSVIISFIYGWEMTFLILSIAPVLAVT 426
Query: 682 GAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTG 861
G + +M +++ AG IA E +IRT+ SL K + L+ +
Sbjct: 427 GMIETAAMTGFANKDKQELKHAGKIATEALENIRTIVSLTREKAFEQMYEEMLQTQHRNT 486
Query: 862 IVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGG 1041
K +G FS+ +Y +YA F +G+ LI G+ F VF A+ G+ ++G
Sbjct: 487 SKKAQIIGSCYAFSHAFIYFAYAAGFRFGAYLIQAGRMTPEGM-FIVFTAIAYGAMAIGK 545
Query: 1042 ALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDI 1221
L + A+ A+ + ++ P ID S EG D +G++ F++V F YP R D+
Sbjct: 546 TLVLAPEYSKAKSGAAHLFALLEKKPNIDSRSQEGKKPDTCEGNLEFREVSFFYPCRPDV 605
Query: 1222 HVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLR 1401
+L+G+SL ++ G +A VGSSGCGKST V LLQR YDP +G+VL DGVD +E+NV LR
Sbjct: 606 FILRGLSLSIERGKTVAFVGSSGCGKSTSVQLLQRLYDPVQGQVLFDGVDAKELNVQWLR 665
Query: 1402 EQIGIVSQEPVLFDGTIYENIKMGNEH--ATHDQVVEACKMANANDFIKRLPDGYGTRVG 1575
QI IV QEPVLF+ +I ENI G+ D++ EA AN + FI+ LP+ Y T+VG
Sbjct: 666 SQIAIVPQEPVLFNCSIAENIAYGDNSRVVPLDEIKEAANAANIHSFIEGLPEKYNTQVG 725
Query: 1576 EKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIV 1755
KG QLSGGQKQR+AIARAL++ PKILLLDEATSALD ++E+ VQ ALD+A+ GRT ++V
Sbjct: 726 LKGAQLSGGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDKARTGRTCLVV 785
Query: 1756 AHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDM 1875
HRLS I+N D I V G I E G+H+EL+ + I++ +
Sbjct: 786 THRLSAIQNADLIVVLHNGKIKEQGTHQELLRNRDIYFKL 825
>gi|39594943|emb|CAE70811.1| Hypothetical protein CBG17574
[Caenorhabditis briggsae]
Length = 1628
Score = 652 bits (1681), Expect = 0.0
Identities = 390/1018 (38%), Positives = 579/1018 (56%), Gaps = 11/1018 (1%)
Frame = +1
Query: 703 MATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYM 882
M ++ + YA AG IA + S +TV SLNG EL + + L++G + GI +
Sbjct: 1 MMGASKAQSYHYANAGGIAYQALSCFKTVISLNGQSYELKSYSSELKLGEKHGIHRALLF 60
Query: 883 GIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLAS 1062
+N + + G+ LI N T D+ I T+F ++ + SL LPH+++
Sbjct: 61 ATSRAVTNFFCSALNGTLLYIGAGLIYNK-TMDQASIVTLFHYMMLSAYSLAEVLPHISN 119
Query: 1063 FGTARGAASTVLRVINSHPKIDPYSLEGILVDN--MKGDISFKDVHFRYPSRKDIHVLKG 1236
A +AS++ ++ S+ D E + D + G I FKDV F YP+R + VLKG
Sbjct: 120 LLNAISSASSIFEILTSND--DNIENEDVPDDQKPINGVIQFKDVRFSYPTRPNAKVLKG 177
Query: 1237 ISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGI 1416
ISLE+K G+ +ALVG+SG GKST+V LL R Y+ G + IDGV+L +++ LR IG+
Sbjct: 178 ISLEVKRGECVALVGASGSGKSTLVQLLLRHYNKDSGSISIDGVELENISLKKLRRNIGV 237
Query: 1417 VSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLS 1596
VSQEP+LFD TI +NI+ GN + ++ +A K ANA +F+ P+G T VGE G QLS
Sbjct: 238 VSQEPILFDTTIEQNIRFGNPECSKFEIFDALKKANAYEFVASFPNGIETIVGEGGAQLS 297
Query: 1597 GGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTI 1776
GGQKQRIAIAR LVKNPKILLLDEATSALD E+ERE+Q AL +A GRTTII+AHRLSTI
Sbjct: 298 GGQKQRIAIARVLVKNPKILLLDEATSALDNESEREIQKALRKASEGRTTIIIAHRLSTI 357
Query: 1777 RNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTXXXXXXXXXXEAG-KDIEDT--ISES 1947
N D+I V G I+ESG+H+ L+ K G + ++ + KD D I E+
Sbjct: 358 NNCDKIIVMSQGQIIESGAHKHLIQKAGAYNNLINSQIFDSEEKQTSQKDPLDINKIKEN 417
Query: 1948 AHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXX 2127
++S L + EE K + ++I + W
Sbjct: 418 SNSLRKSSKGSQAS---------LTDTPEE-KEVSSGFWEIINECRPQYFWLLTAIIGSF 467
Query: 2128 XXXSVTPVFALVYAEIFNVYSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCG 2307
P+ A + + YS+ + + +FW MF +G+ + +T+ C GR
Sbjct: 468 MQGLSPPLLAQLIVRTYKAYSMEGEDILIYGHFWASMFFALGLIRPITAYTTHYCYGRVA 527
Query: 2308 ESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIV 2484
E L+ +LR ++F ++L AFYD+ ++ +L R TDA NV+ V +RL + ++V
Sbjct: 528 EKLSTRLRIKSFHHMLSLPCAFYDESKNSPTRLANRLNTDASNVKGAVDSRLGTIFTTLV 587
Query: 2485 TICGALGIGFYYGWQXXXXXXXXXXXXXMGG--YFEMQMRFGKQIRDTQLLEEAGKVASQ 2658
+ ++ + YY W+ G Y ++ KQ D+ L+E++ K+A +
Sbjct: 588 SFLVSISVASYYSWKLTIQIILFFPILYFGKRCYDNATVQSVKQ--DSALIEKSNKIAVE 645
Query: 2659 AVEHIRTVHSLNRQEQFHFTYC---EYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAA 2829
+ +I+TV SLN ++ E LR+ + A T G FS +F YAA+
Sbjct: 646 VLNNIKTVRSLNMGDKVMSMIIGELEVLRKKYRWK---AITLGLANGFSVICHYFFYAAS 702
Query: 2830 FYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPT 3009
F G+ + Q+ + P+++Y F +S+ M+GN ++P+ KA AA L+F L++ P
Sbjct: 703 FKFGTHLILQREILPMNMYVSFITLSYTSNMVGNVMLYLPEYRKAVHAAGLIFNLLKTPA 762
Query: 3010 PIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKS 3189
+ S G ++ G + N+ F+Y R D VL+ L +K GKT+ALVG SG GKS
Sbjct: 763 TMPYDSKEGSMEIKNGVVKGSNISFHYHQRLDHMVLKNVNLSLKPGKTLALVGPSGSGKS 822
Query: 3190 TIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNR 3369
+ + L+ERFY D G + ID +++ ++NI LR + +V+QEP LF+C+I +N+ YG
Sbjct: 823 SFISLIERFYQVDTGCVKIDNEDVEDINIHHLRSNLGLVAQEPVLFNCSIRQNLLYGLEE 882
Query: 3370 NVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLL 3549
V +I +A + AN +FI P+G +T VGE G QLSGGQKQRIAIARA++R+P +LL
Sbjct: 883 LVEEIKIEKALRTANALDFIQKFPEGLNTIVGEHGAQLSGGQKQRIAIARAILRNPKILL 942
Query: 3550 LDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGT 3723
LDEATSALD++SEK+VQ ALD A + + +V+AHRLSTI N+D IA+ G++VE+G+
Sbjct: 943 LDEATSALDSDSEKLVQNALDTAIERLSTVVVAHRLSTIVNADSIAVFENGQVVEQGS 1000
Score = 305 bits (782), Expect = 4e-81
Identities = 184/500 (36%), Positives = 280/500 (55%), Gaps = 5/500 (1%)
Frame = +1
Query: 349 YLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTG--NLTARL 522
+ LG++ T+Y C+ AE+L +LR +L ++D+ + L RL
Sbjct: 505 FFALGLIRPITAYTTHYCYGRVAEKLSTRLRIKSFHHMLSLPCAFYDESKNSPTRLANRL 564
Query: 523 TDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKS 702
D V+ + + + +FL V +YSW +T+ ++ F P++ K
Sbjct: 565 NTDASNVKGAVDSRLGTIFTTLVSFLVSISVASYYSWKLTIQIILFFPILYFG--KRCYD 622
Query: 703 MATRTRVEQETYAV--AGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYC 876
AT V+Q++ + + IA E ++I+TV SLN + + LEV R+ K
Sbjct: 623 NATVQSVKQDSALIEKSNKIAVEVLNNIKTVRSLNMGDKVMSMIIGELEVLRKKYRWKAI 682
Query: 877 YMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHL 1056
+G+ GFS +C Y YA +F +G+ LI+ + + F + S +G + +L
Sbjct: 683 TLGLANGFSVICHYFFYAASFKFGTHLILQREILPMNM-YVSFITLSYTSNMVGNVMLYL 741
Query: 1057 ASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKG 1236
+ A AA + ++ + P PY + ++ G + ++ F Y R D VLK
Sbjct: 742 PEYRKAVHAAGLIFNLLKT-PATMPYDSKEGSMEIKNGVVKGSNISFHYHQRLDHMVLKN 800
Query: 1237 ISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGI 1416
++L LK G +ALVG SG GKS+ ++L++RFY G V ID D+ ++N+H LR +G+
Sbjct: 801 VNLSLKPGKTLALVGPSGSGKSSFISLIERFYQVDTGCVKIDNEDVEDINIHHLRSNLGL 860
Query: 1417 VSQEPVLFDGTIYENIKMGNEHATHDQVVE-ACKMANANDFIKRLPDGYGTRVGEKGVQL 1593
V+QEPVLF+ +I +N+ G E + +E A + ANA DFI++ P+G T VGE G QL
Sbjct: 861 VAQEPVLFNCSIRQNLLYGLEELVEEIKIEKALRTANALDFIQKFPEGLNTIVGEHGAQL 920
Query: 1594 SGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLST 1773
SGGQKQRIAIARA+++NPKILLLDEATSALD+++E+ VQ ALD A +T++VAHRLST
Sbjct: 921 SGGQKQRIAIARAILRNPKILLLDEATSALDSDSEKLVQNALDTAIERLSTVVVAHRLST 980
Query: 1774 IRNVDRIFVFKAGNIVESGS 1833
I N D I VF+ G +VE GS
Sbjct: 981 IVNADSIAVFENGQVVEQGS 1000
Score = 277 bits (708), Expect = 2e-72
Identities = 161/385 (41%), Positives = 232/385 (59%), Gaps = 5/385 (1%)
Frame = +1
Query: 2638 AGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFM 2817
AG +A QA+ +TV SLN Q +Y L+ KH +FA S+++ F
Sbjct: 15 AGGIAYQALSCFKTVISLNGQSYELKSYSSELK----LGEKHGIHRALLFATSRAVTNFF 70
Query: 2818 YAAA----FYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLL 2985
+A Y+G+ + + M + +F + + I +++ A +AS +
Sbjct: 71 CSALNGTLLYIGAGLIYNKTMDQASIVTLFHYMMLSAYSLAEVLPHISNLLNAISSASSI 130
Query: 2986 FYLI-EHPTPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVAL 3162
F ++ + I++ KPI G I ++V F+YPTR + KVL+G +L++K G+ VAL
Sbjct: 131 FEILTSNDDNIENEDVPDDQKPINGVIQFKDVRFSYPTRPNAKVLKGISLEVKRGECVAL 190
Query: 3163 VGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIG 3342
VG SG GKST++ LL R YN+D G I IDG + N+++ LR + +VSQEP LFD TI
Sbjct: 191 VGASGSGKSTLVQLLLRHYNKDSGSISIDGVELENISLKKLRRNIGVVSQEPILFDTTIE 250
Query: 3343 ENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARA 3522
+NI +G N + EI +A K AN + F+ P+G +T VGE G QLSGGQKQRIAIAR
Sbjct: 251 QNIRFG-NPECSKFEIFDALKKANAYEFVASFPNGIETIVGEGGAQLSGGQKQRIAIARV 309
Query: 3523 LVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEG 3702
LV++P +LLLDEATSALD ESE+ +Q+AL A +GRT ++IAHRLSTI N D I ++S+G
Sbjct: 310 LVKNPKILLLDEATSALDNESEREIQKALRKASEGRTTIIIAHRLSTINNCDKIIVMSQG 369
Query: 3703 KIVEKGTHDELIRKSEIYQKFCETQ 3777
+I+E G H LI+K+ Y +Q
Sbjct: 370 QIIESGAHKHLIQKAGAYNNLINSQ 394
Score = 264 bits (675), Expect = 1e-68
Identities = 185/593 (31%), Positives = 279/593 (46%), Gaps = 11/593 (1%)
Frame = +1
Query: 1456 ENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARAL 1635
ENI GN +AT ++ EA + ANA DF+ P G + VGE+G QLSGGQKQRIAIAR L
Sbjct: 1049 ENILFGNPNATVSEIYEALRKANAYDFVNSFPKGIKSVVGERGAQLSGGQKQRIAIARTL 1108
Query: 1636 VKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGN 1815
V+NPKILLL EATSALD E+E VQ AL++A GRTTI++AHRLSTIRN +I V G
Sbjct: 1109 VRNPKILLL-EATSALDNESEHVVQRALEKASEGRTTIVIAHRLSTIRNASKIIVMDKGE 1167
Query: 1816 IVESG-----SHEELMSKQGIFYDMTXXXXXXXXXXEAGKDIEDTISESAHSHLXXXXXX 1980
IV+ G S +EL ++Q EA D
Sbjct: 1168 IVKVGNVLDHSSQELSARQ------DSSRTEFSETNEAQDD------------------- 1202
Query: 1981 XXXXXXXXXIHQLAEEVEECKAPPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFAL 2160
I +L E+ E A +++ +I K +
Sbjct: 1203 --------EIKRLMNELTEEGAQKSNLREIIKMCKPDYCLFLTALAGSALQGLSYQISVK 1254
Query: 2161 VYAEIFNVYSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEA 2340
+ + +++ + + +FW +L+ + + LG+ E L+ +LR ++
Sbjct: 1255 LTVRAYEAFAMNGEDIMIYGHFWAFAILLLALFRPITLRCQYYYLGKVSERLSTRLRMKS 1314
Query: 2341 FKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVR-YVFTRLPVVLASIVTICGALGIGFY 2517
FK+L+ +FYDD +H +L R TDA NV+ V RL V + V I A+
Sbjct: 1315 FKHLMSLPCSFYDDPKHSAIRLSNRLNTDASNVKASVDDRLGSVFMTFVAISIAISTSTV 1374
Query: 2518 YGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNR 2697
Y W+ + Y + G +DT E + + A +A+EHIRTV +LN
Sbjct: 1375 YSWKMTIQVLLLCPILYLAEYCYERAIDGAIEKDTLAFENSNRAAIEAIEHIRTVRALNM 1434
Query: 2698 QEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPI 2877
+++ ++L++ N+ K A GA F F++Y+ +F G+ + + P+
Sbjct: 1435 EDRIMDMVADHLQKSHNSCFKRAVIQGAANGFFCCCFFYIYSISFKFGTWLAMHKEIMPM 1494
Query: 2878 DVYRVFFAISFCGQ-----MIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIV 3042
+ Y V ++ M G+ +++PD KA AA L+F+L +P + S G
Sbjct: 1495 ETYMVSMTLTLTSTYDLWLMAGSAVAYLPDYKKAAHAAGLIFHLFTYPETMAYGSKDGTK 1554
Query: 3043 KPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMG 3201
G + N+ F+Y R D +L G L ++ GKT+AL G TI+G
Sbjct: 1555 NIKLGKVVGENLKFHYEQRPDKTILDGVNLRVEPGKTLAL------GLDTIVG 1601
Score = 140 bits (352), Expect = 3e-31
Identities = 75/127 (59%), Positives = 95/127 (74%)
Frame = +1
Query: 3340 GENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIAR 3519
GENI +G N N T EI EA + AN ++F+ P G + VGE+G QLSGGQKQRIAIAR
Sbjct: 1048 GENILFG-NPNATVSEIYEALRKANAYDFVNSFPKGIKSVVGERGAQLSGGQKQRIAIAR 1106
Query: 3520 ALVRSPSVLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSE 3699
LVR+P +LLL EATSALD ESE +VQ AL+ A +GRT +VIAHRLSTI+N+ I ++ +
Sbjct: 1107 TLVRNPKILLL-EATSALDNESEHVVQRALEKASEGRTTIVIAHRLSTIRNASKIIVMDK 1165
Query: 3700 GKIVEKG 3720
G+IV+ G
Sbjct: 1166 GEIVKVG 1172
Score = 85.9 bits (211), Expect = 7e-15
Identities = 72/316 (22%), Positives = 131/316 (40%), Gaps = 8/316 (2%)
Frame = +1
Query: 352 LVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD--KQQTGNLTARLT 525
L+L + T Q +ERL +LR K ++ ++D K L+ RL
Sbjct: 1282 LLLALFRPITLRCQYYYLGKVSERLSTRLRMKSFKHLMSLPCSFYDDPKHSAIRLSNRLN 1341
Query: 526 DDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSM 705
D V+ + D+ + F A YSW MT+ ++ P++ L A+
Sbjct: 1342 TDASNVKASVDDRLGSVFMTFVAISIAISTSTVYSWKMTIQVLLLCPILYL--AEYCYER 1399
Query: 706 ATRTRVEQETYAV--AGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCY 879
A +E++T A + A E IRTV +LN R +D + L+ + +
Sbjct: 1400 AIDGAIEKDTLAFENSNRAAIEAIEHIRTVRALNMEDRIMDMVADHLQKSHNSCFKRAVI 1459
Query: 880 MGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSL----GGAL 1047
G GF C + Y+++F +G+ L ++ L+ + L G A+
Sbjct: 1460 QGAANGFFCCCFFYIYSISFKFGTWLAMHKEIMPMETYMVSMTLTLTSTYDLWLMAGSAV 1519
Query: 1048 PHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHV 1227
+L + A AA + + ++P+ Y + + G + +++ F Y R D +
Sbjct: 1520 AYLPDYKKAAHAAGLIFHLF-TYPETMAYGSKDGTKNIKLGKVVGENLKFHYEQRPDKTI 1578
Query: 1228 LKGISLELKAGDKIAL 1275
L G++L ++ G +AL
Sbjct: 1579 LDGVNLRVEPGKTLAL 1594
>gi|27368843|emb|CAD59579.1| MDR-like ABC transporter [Oryza sativa
(japonica cultivar-group)]
Length = 1242
Score = 642 bits (1657), Expect = 0.0
Identities = 423/1255 (33%), Positives = 651/1255 (51%), Gaps = 32/1255 (2%)
Frame = +1
Query: 109 GIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPE 288
G+ Y VD LL+ GTV ++IHG FP+ ++LG + G + + E
Sbjct: 43 GLLCYADAVDWLLMALGTVGSIIHGMAFPVGYLLLGKALDAY----------GTNINDQE 92
Query: 289 GLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILR 468
G+V +VV + ++Y+ L V+I+C+ +ER + ++R +L+++L
Sbjct: 93 GMVHALY-----KVVPF-VWYMAAATLP--AGMVEISCWIYSSERQLARMRLAFLRSVLN 144
Query: 469 QQIQWFDKQ-QTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTL 645
Q++ FD T + +T+ + +++ +G+K V F+ F AG + F W + L
Sbjct: 145 QEVGAFDTDLTTAKIITGVTNHMSVIQDAIGEKLGHFVASFSTFFAGIIIAFASCWEVAL 204
Query: 646 VMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDR 825
+ PLI++ GA +K M + + A +I E+T S I+TV S G KR +
Sbjct: 205 LSFLVIPLILVIGATYTKQMNGISLSRNAIVSEATSIVEQTLSHIKTVFSFVGEKRAMRS 264
Query: 826 FY----NALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLI 993
F N ++ ++ ++K GIG+G + S+AL W G+
Sbjct: 265 FVRCMDNQYKLSKKEAVIK----GIGLGLFQAVTFCSWALMVWIGAV------------- 307
Query: 994 FTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGD 1173
AV S + GG + + S GA V +VI P I Y G ++ + G+
Sbjct: 308 -----AVTSRKATGGGTIAAIMSI--LFGAXKXVFKVIKRKPSIS-YEKHGSVLGKVHGE 359
Query: 1174 ISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRV 1353
I F+ VHF YPSR+D +L+G SL + AG +ALVGSSGCGKST+++LLQRFYDPT G +
Sbjct: 360 IKFRRVHFAYPSRQDKPILQGFSLSIPAGKVVALVGSSGCGKSTVISLLQRFYDPTSGSI 419
Query: 1354 LIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANAND 1533
LIDG ++++++ SLR I VSQEP LF GTI +N+++G A D++ +A + AN +
Sbjct: 420 LIDGHSIKKLDLESLRRNIASVSQEPSLFSGTIKDNLRIGKMDANDDEITKAARTANVHS 479
Query: 1534 FIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQG 1713
FI +LP+ Y T VGE+GVQLSGGQKQRIAIARA++K+P ILLLDEATSALD+E+E+ VQ
Sbjct: 480 FISKLPNEYLTEVGERGVQLSGGQKQRIAIARAMLKDPPILLLDEATSALDSESEKLVQD 539
Query: 1714 ALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYDMTX---- 1881
AL++A +GRT I++AHR+STI N D I V + G + ++G+H+EL+ K + ++
Sbjct: 540 ALEKAMSGRTVILIAHRMSTIVNADTIVVVENGKVAQTGTHQELIEKSTFYSNVCSMQNI 599
Query: 1882 -XXXXXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQL--AEEVEECKAPP 2052
+ IED I E L + QL + +E +
Sbjct: 600 EKEAGTRVASSSDNVIEDEIDEVYDRQL------SPKQGQQNKLEQLNSKQPKQEVRKEI 653
Query: 2053 TSMFKI-FKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEI-FNVYSLPADQMQAN--- 2217
F++ + D + P+F I Y L A + +
Sbjct: 654 HPFFRLWYGLQKDDIAKILLGSSSAAISGISKPLFGYFIMTIGVAYYDLDAKRKVSKYSL 713
Query: 2218 VYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGT 2397
++F G+ L F G GE LR F ++LR ++ +++ ++G
Sbjct: 714 IFFTAGVITLASNIF------QHYIYGVVGEKAMKILREAIFSSVLRNELGWFEKPKNGV 767
Query: 2398 GKLCTRFATDAPNVRYVFT-RLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMG 2574
G L +R +D V+ + + R+ V++ I +I A + Y W+ +G
Sbjct: 768 GFLTSRIVSDTSTVKTIISDRMAVIVQCISSILIATVVSMYVNWRMGLVSWAVMPCHFIG 827
Query: 2575 GYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTN 2754
G + + G +E +AS+A +IRTV S +++ L+EP
Sbjct: 828 GLIQAKAAKGFYGDSAIAHQELVSLASEAASNIRTVASFVYEDEIIKKAELSLQEPMRVT 887
Query: 2755 LKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNT 2934
+ YG V S L +A A + ++ V ++ + R + S I
Sbjct: 888 KIESMKYGVVQGISLCLWNIAHAVALWYTTVLVQRKQASFENSIRSYQIFSLTVPSITEL 947
Query: 2935 TSFIPDVVKARLAASLLFYLIEHPTPI-----DSLSDSGIVKPITGNISIRNVFFNYPTR 3099
+ IP V+ A + F +++ T I ++ SD ++ G ++V FNYP+R
Sbjct: 948 WTLIPMVMSAIAVLNPAFEMLDRDTQIVPDRPENPSDGWLM----GRTEFQDVSFNYPSR 1003
Query: 3100 KDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNIS 3279
+ +L GF+L I+ G+ VALVG SG GKS+++ LL RFY+ +G ++ID NI++ N+
Sbjct: 1004 PEVTILDGFSLVIEPGQRVALVGPSGAGKSSVLALLLRFYDPQRGRVLIDNKNIKDYNLR 1063
Query: 3280 SLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTH 3459
LR+Q+ +V QEP LF+ +I +NI YG + + EI++AA ANIH FI LP GYDT
Sbjct: 1064 WLRKQIGLVQQEPILFNSSIRDNISYG-SEETSETEIIQAAMEANIHEFISSLPKGYDTV 1122
Query: 3460 VGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDA-------- 3615
VG KG+QLSGGQKQRIAIAR L++ P +LLLDEATSALD ESE++V +L A
Sbjct: 1123 VGRKGSQLSGGQKQRIAIARTLLKRPVILLLDEATSALDGESERVVMSSLGAKDWKDRNE 1182
Query: 3616 AKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSE-IYQKFCETQ 3777
T + +AHRLST+ NSD I ++ GK+VE G H LI + +Y + Q
Sbjct: 1183 GSSKITSITVAHRLSTVINSDTIVVMERGKVVELGNHHTLITADDGVYSRLFHLQ 1237
Score = 301 bits (772), Expect = 6e-80
Identities = 197/598 (32%), Positives = 318/598 (52%), Gaps = 16/598 (2%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNP 285
+ ++Y Q D+ ++ G+ +A I G PL F++ +
Sbjct: 657 FRLWYGLQKDDIAKILLGSSSAAISGISKPLFGY----------------FIMTI----- 695
Query: 286 EGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAIL 465
G+ LD +V KY + + GV+ ++ Q + E+ + LR+ ++L
Sbjct: 696 -GVAYYDLDA-KRKVSKYSLIFFTAGVITLASNIFQHYIYGVVGEKAMKILREAIFSSVL 753
Query: 466 RQQIQWFDKQQTGN--LTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSM 639
R ++ WF+K + G LT+R+ D V+ + D+ A++VQ ++ L V + +W M
Sbjct: 754 RNELGWFEKPKNGVGFLTSRIVSDTSTVKTIISDRMAVIVQCISSILIATVVSMYVNWRM 813
Query: 640 TLVMMGFAPLIVLSG---AKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHK 810
LV P + G AK +K + + + ++A E S+IRTV S
Sbjct: 814 GLVSWAVMPCHFIGGLIQAKAAKGFYGDSAIAHQELV---SLASEAASNIRTVASFVYED 870
Query: 811 RELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYS-SYALAFWYGSTLIIN-DPTFDR 984
+ + +L+ + ++ G+ G S LC+++ ++A+A WY + L+ +F+
Sbjct: 871 EIIKKAELSLQEPMRVTKIESMKYGVVQGIS-LCLWNIAHAVALWYTTVLVQRKQASFEN 929
Query: 985 GL-IFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDN 1161
+ + +F + T L +P + S A + +++ +I P E
Sbjct: 930 SIRSYQIFSLTVPSITELWTLIPMVMS---AIAVLNPAFEMLDRDTQIVPDRPENPSDGW 986
Query: 1162 MKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPT 1341
+ G F+DV F YPSR ++ +L G SL ++ G ++ALVG SG GKS+++ LL RFYDP
Sbjct: 987 LMGRTEFQDVSFNYPSRPEVTILDGFSLVIEPGQRVALVGPSGAGKSSVLALLLRFYDPQ 1046
Query: 1342 KGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMA 1521
+GRVLID ++++ N+ LR+QIG+V QEP+LF+ +I +NI G+E + ++++A A
Sbjct: 1047 RGRVLIDNKNIKDYNLRWLRKQIGLVQQEPILFNSSIRDNISYGSEETSETEIIQAAMEA 1106
Query: 1522 NANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAER 1701
N ++FI LP GY T VG KG QLSGGQKQRIAIAR L+K P ILLLDEATSALD E+ER
Sbjct: 1107 NIHEFISSLPKGYDTVVGRKGSQLSGGQKQRIAIARTLLKRPVILLLDEATSALDGESER 1166
Query: 1702 EVQGAL--------DQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMS 1851
V +L ++ + T+I VAHRLST+ N D I V + G +VE G+H L++
Sbjct: 1167 VVMSSLGAKDWKDRNEGSSKITSITVAHRLSTVINSDTIVVMERGKVVELGNHHTLIT 1224
Score = 298 bits (762), Expect = 9e-79
Identities = 180/501 (35%), Positives = 269/501 (52%), Gaps = 2/501 (0%)
Frame = +1
Query: 2287 NCLGRCGESLTMKLRFEAFKNLLRQDIAFYD-DLRHGTGKLCTRFATDAPNVR-YVFTRL 2460
+C E ++R +++L Q++ +D DL T K+ T ++ + +L
Sbjct: 121 SCWIYSSERQLARMRLAFLRSVLNQEVGAFDTDLT--TAKIITGVTNHMSVIQDAIGEKL 178
Query: 2461 PVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEA 2640
+AS T + I F W+ + G + G + ++ EA
Sbjct: 179 GHFVASFSTFFAGIIIAFASCWEVALLSFLVIPLILVIGATYTKQMNGISLSRNAIVSEA 238
Query: 2641 GKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMY 2820
+ Q + HI+TV S +++ ++ + + + K A G Q++ F +
Sbjct: 239 TSIVEQTLSHIKTVFSFVGEKRAMRSFVRCMDNQYKLSKKEAVIKGIGLGLFQAVTFCSW 298
Query: 2821 AAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIE 3000
A ++G++ V + G T + I ++ A +F +I+
Sbjct: 299 ALMVWIGAVAVTSRKATG-----------------GGTIAAIMSILFG--AXKXVFKVIK 339
Query: 3001 HPTPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGC 3180
I ++ + G I R V F YP+R+D +LQGF+L I AGK VALVG SGC
Sbjct: 340 RKPSISYEKHGSVLGKVHGEIKFRRVHFAYPSRQDKPILQGFSLSIPAGKVVALVGSSGC 399
Query: 3181 GKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYG 3360
GKST++ LL+RFY+ G I+IDG +I+ L++ SLR + VSQEP+LF TI +N+ G
Sbjct: 400 GKSTVISLLQRFYDPTSGSILIDGHSIKKLDLESLRRNIASVSQEPSLFSGTIKDNLRIG 459
Query: 3361 TNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPS 3540
+ EI +AA+ AN+H+FI LP+ Y T VGE+G QLSGGQKQRIAIARA+++ P
Sbjct: 460 -KMDANDDEITKAARTANVHSFISKLPNEYLTEVGERGVQLSGGQKQRIAIARAMLKDPP 518
Query: 3541 VLLLDEATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKG 3720
+LLLDEATSALD+ESEK+VQ+AL+ A GRT ++IAHR+STI N+D I +V GK+ + G
Sbjct: 519 ILLLDEATSALDSESEKLVQDALEKAMSGRTVILIAHRMSTIVNADTIVVVENGKVAQTG 578
Query: 3721 THDELIRKSEIYQKFCETQRI 3783
TH ELI KS Y C Q I
Sbjct: 579 THQELIEKSTFYSNVCSMQNI 599
>gi|49092568|ref|XP_407745.1| hypothetical protein AN3608.2
[Aspergillus nidulans FGSC A4]
gi|40740626|gb|EAA59816.1| hypothetical protein AN3608.2 [Aspergillus
nidulans FGSC A4]
Length = 1266
Score = 642 bits (1655), Expect = 0.0
Identities = 414/1261 (32%), Positives = 644/1261 (50%), Gaps = 37/1261 (2%)
Frame = +1
Query: 106 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNP 285
+ ++ Y+ D ++ +TG AA+ GA PL+ +V G + +DN N
Sbjct: 30 FRVWGYSSVQDHVIRVTGLFAAIACGAALPLMTLVFGTL---------------IDNFND 74
Query: 286 EGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAIL 465
G +S DEF S V + +++ L + +F S AC A R V LR +++++IL
Sbjct: 75 WGAGKLSPDEFRSHVSQNALWFTYLFISIFVLSSFNTACLRLTATRCVRALRHDFIRSIL 134
Query: 466 RQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTL 645
RQ + +FD G + L+++ + V GLG+K + ++ A A + V F W +TL
Sbjct: 135 RQDLSYFDNCLPGTVATVLSNNADLVEIGLGEKLGIAIEGVAQLCAAFVVAFARQWKLTL 194
Query: 646 VMMGFAPLIVLSGAKMSKSMATRTRVEQETYAV---AGAIAEETFSSIRTVHSLNGHKRE 816
V+ PL +L + ++ TR+ + A+ AG IAEE +S V + N +
Sbjct: 195 VVAATLPLAMLV---IVVTVILETRITTKILAIYSKAGGIAEEALASTHIVKAYNAASKL 251
Query: 817 LDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIF 996
R+ + LE Q G+ + GI G M+ +YALA++YG L++ G +
Sbjct: 252 QARYDSYLERATQLGVKRGPIRGIQYGAQFAIMFCAYALAWFYGIRLLVKGEIESGGYLI 311
Query: 997 TVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDI 1176
TV +VL GS SL P + AA + +VI+ P ID S +G + + G I
Sbjct: 312 TVLTSVLIGSQSLTLIGPFIGEVSKTAAAAQELFQVIDRKPNIDSLSSDGRTLTGVTGHI 371
Query: 1177 SFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVL 1356
SF++V F YPSR + VL ++++ +AG A+VGSSG GKSTI+ L+ RF+DP G VL
Sbjct: 372 SFRNVSFAYPSRPSVRVLDDVTVDFEAGKTTAIVGSSGSGKSTILALVSRFFDPVSGSVL 431
Query: 1357 IDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMG---------NEHATHDQVVEA 1509
+DG + E+N+ LR QIG V QEPVLF +I+ N+ G EH +V EA
Sbjct: 432 LDGHPIHELNIRWLRGQIGSVQQEPVLFSESIFANVCHGFFRTDMDLLPEHERRIRVQEA 491
Query: 1510 CKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDT 1689
C+ A A+ FI+ LP+ Y T VG LSGGQKQRIAIAR++++NP ILLLDEATSALD
Sbjct: 492 CEAAFAHHFIQGLPEQYDTPVGAGDGLLSGGQKQRIAIARSIIRNPPILLLDEATSALDP 551
Query: 1690 EAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFY 1869
AE VQ AL+ RTTIIVAHRLST++ D I V + G +VE GSH EL++K+G ++
Sbjct: 552 NAEGTVQAALNNVSKTRTTIIVAHRLSTVQRADNIVVLRKGRVVEQGSHRELLAKKGTYF 611
Query: 1870 DMTXXXXXXXXXXEAGKDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKAP 2049
D+ AG + T + A S L Q ++ K
Sbjct: 612 DLVAAQTEDGIISTAG---DQTGTSEADSVLVKKAAVEDYNSAMSS--QSSKATAHEKRV 666
Query: 2050 PTSMFKIFKFNGDKVGW--XXXXXXXXXXXXSVTPVFALVYAEIFNVYSLP----ADQMQ 2211
P G W SV PV A+V++ ++ P A +M
Sbjct: 667 PLLKCLFILLRGRLQLWPLFFCGLIVSIGAGSVFPVQAVVFSRAILIFQFPLPAMASEML 726
Query: 2212 ANVYFWCGMFVLMGITFFV-----GFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFY 2376
FW +++++ ++ + GFF + L+ R F +L QD++F+
Sbjct: 727 HKGNFWGIIYIVLAVSVLICYAGLGFFFTV-----AASFLSGTYRSRYFAAMLNQDVSFF 781
Query: 2377 DDLRHGTGKLCTRFATDAPNVRYVFTR-LPVVLASIVTICGALGIGFYYGWQXXXXXXXX 2553
++ G + + +TD + + + L +L +V + + + GW+
Sbjct: 782 EEEDQSAGVMTGQLSTDPQRIEDLISLCLGFILLVVVNVLASCILALAVGWRLALVAIFG 841
Query: 2554 -XXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEY 2730
+ GY +++ Q R T+L E+ + A++A+ IRTV SL +E+ Y E
Sbjct: 842 CLPPLFLAGYVRVRLEITCQERTTRLYLESARFATEAISAIRTVASLTLEEKVIQMYDER 901
Query: 2731 LREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISF 2910
L ++ + +SL F+ G ++Q + VF A+ F
Sbjct: 902 LSHTSPKFIRITLVSAILLGLCESLYLATLGLIFWYGVKLLSQGEYNVETFFMVFVAVIF 961
Query: 2911 CGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGN--ISIRNVFF 3084
GQ G + + KA AA+ + +++ I++ + + + I ++V F
Sbjct: 962 GGQAAGFLLGYTVNTAKAHTAANNIIHILGSRPSINASTGKQETVQLDSDTAIEFKDVHF 1021
Query: 3085 NYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIR 3264
+YP R VLQG + +K G+ + LVG SGCGK+T++ LLERFY G I I+G +
Sbjct: 1022 SYPARPTVPVLQGLSFKVKKGEHIGLVGASGCGKTTVISLLERFYEAGSGEIFINGIPLH 1081
Query: 3265 NLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQE--------IVEAAKMANIH 3420
++++ S R ++ +V+Q PTL+ +I +N+ G + + +E + +A K ANI
Sbjct: 1082 DIDVHSHRARIGLVTQNPTLYQGSIRDNVLIGISISHQNEELDSQIEEKLTKAYKDANIQ 1141
Query: 3421 NFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQ 3600
+FI LP+G T G +G LSGGQ+QRIAIARAL+R P +LL DEATSALDTE+E++VQ
Sbjct: 1142 DFIQSLPEGQQTDPGTRGLALSGGQRQRIAIARALIRDPELLLFDEATSALDTENERLVQ 1201
Query: 3601 EALDAAKQ--GRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIYQKFCET 3774
EA++ GRT + +AHRL+T++ D I ++ EG++ E+GTH EL+ + Y +
Sbjct: 1202 EAIERVSHGPGRTTISVAHRLTTVRRCDRILVLHEGRVEEEGTHAELMARGGRYYQMVLA 1261
Query: 3775 Q 3777
Q
Sbjct: 1262 Q 1262
>gi|16304396|gb|AAL15148.1| multidrug resistance transporter-like
protein [Pseudopleuronectes americanus]
Length = 817
Score = 640 bits (1652), Expect = 0.0
Identities = 350/794 (44%), Positives = 484/794 (60%), Gaps = 20/794 (2%)
Frame = +1
Query: 1456 ENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARAL 1635
ENI+ G T ++ +A K ANA DFI +LP + T VG++G Q+SGGQKQR+AIARAL
Sbjct: 18 ENIRYGRLDVTQQEIEQAAKEANAYDFIMKLPQKFDTLVGDRGTQMSGGQKQRVAIARAL 77
Query: 1636 VKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGN 1815
V+NPKILLLDEATSALD E+E VQ ALD+ + GRTTIIVAHRLSTIRN D I F+ G
Sbjct: 78 VRNPKILLLDEATSALDAESETIVQAALDKVRLGRTTIIVAHRLSTIRNADVIAGFQDGK 137
Query: 1816 IVESGSHEELMSKQGIFYDMTXXXXXXXXXXEAGKDIEDTISESA-----HSHLXXXXXX 1980
+ E G+H +LM K+GI++ + ++ E ++ E + HS
Sbjct: 138 VAEVGTHSQLMEKKGIYHRLVTTQTFQDVEEGEKEEEELSVDEKSPLVDSHSECTPYRRK 197
Query: 1981 XXXXXXXXXIHQLAEEVEECKA-----------PPTSMFKIFKFNGDKVGWXXXXXXXXX 2127
EE E+ ++ PP S FK+ + N + +
Sbjct: 198 TTRGSSMTVSEGGKEEKEKTESDKDEPEEDEIVPPVSFFKVLRLNLPEWPYILVGTICAI 257
Query: 2128 XXXSVTPVFALVYAEIFNVYSLPADQM-QANVYFWCGMFVLMGITFFVGFFTSANCLGRC 2304
++ PVFA+++++I V++ ++ + + MF ++G FV F C G+
Sbjct: 258 INGAMQPVFAIIFSKIITVFAETDQELVRQRATLFSLMFAVIGGVSFVTMFLQGFCFGKS 317
Query: 2305 GESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRYVF-TRLPVVLASI 2481
GE LT+KLR AFK ++RQD+ ++D+ ++ G L TR ATDA V+ R+ + +
Sbjct: 318 GEILTLKLRLGAFKAMMRQDLGWFDNPKNSVGALTTRLATDAAQVQGATGVRMATLAQNF 377
Query: 2482 VTICGALGIGFYYGWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQA 2661
+ ++ I F YGW+ + G EM++ G + D + LE+AGK++++A
Sbjct: 378 ANMGTSVIISFVYGWELTLLILAVVPAMVLAGAVEMKLLTGHAVEDKKELEKAGKISTEA 437
Query: 2662 VEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLG 2841
+E+IRTV SL R+ +F Y E L P+ + K AH YG FAFSQ++I+F YA F G
Sbjct: 438 IENIRTVASLTREPKFESLYHENLEVPYKNSTKKAHVYGLTFAFSQAMIYFAYAGCFRFG 497
Query: 2842 SIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDS 3021
+ + + M V+ V + + IG SF P+ KA+++AS L LI ID+
Sbjct: 498 AWLIEEGRMDVQGVFLVISTVLYGAMAIGEANSFTPNYAKAKMSASYLMQLINLEPAIDN 557
Query: 3022 LSDSGIVKP-ITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIM 3198
LS G GN+ NV FNYP+R D +LQG L++K G+T+ALVG SGCGKSTI+
Sbjct: 558 LSQEGETPDSFDGNVHFENVRFNYPSRPDVPILQGLDLEVKRGETLALVGSSGCGKSTII 617
Query: 3199 GLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNV- 3375
LLERFY+ +G + +D N + LNI LR Q+ IVSQEPTLFDCT+ +NI YG N +
Sbjct: 618 QLLERFYDPREGSVALDNVNTKRLNIHWLRSQMGIVSQEPTLFDCTLAQNIAYGDNSRIA 677
Query: 3376 TYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLD 3555
T EIV AAK ANIH+FI LP+ YDT G+KGTQLSGGQKQRIAIARA++R+P +LLLD
Sbjct: 678 TMDEIVAAAKSANIHSFIQELPEKYDTQAGDKGTQLSGGQKQRIAIARAILRNPMLLLLD 737
Query: 3556 EATSALDTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDEL 3735
EATSALDTESEK+VQEALD A +GRTC+++AHRLSTIQN+D IA++ G +VE+GTH +L
Sbjct: 738 EATSALDTESEKVVQEALDQASKGRTCIIVAHRLSTIQNADRIAVLQGGVVVEQGTHQQL 797
Query: 3736 IRKSEIYQKFCETQ 3777
+ K +Y TQ
Sbjct: 798 LAKRGVYHMLVTTQ 811
Score = 429 bits (1102), Expect = e-118
Identities = 239/578 (41%), Positives = 345/578 (59%), Gaps = 4/578 (0%)
Frame = +1
Query: 148 LITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSE 327
++ GT+ A+I+GA P+ AI+ + TVF +
Sbjct: 249 ILVGTICAIINGAMQPVFAIIFSKIITVFAETDQ--------------------ELVRQR 288
Query: 328 VVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD--KQQT 501
+ + + V+G + F T ++Q CF E L KLR KA++RQ + WFD K
Sbjct: 289 ATLFSLMFAVIGGVSFVTMFLQGFCFGKSGEILTLKLRLGAFKAMMRQDLGWFDNPKNSV 348
Query: 502 GNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLS 681
G LT RL D +V+ G + A L Q FA + F Y W +TL+++ P +VL+
Sbjct: 349 GALTTRLATDAAQVQGATGVRMATLAQNFANMGTSVIISFVYGWELTLLILAVVPAMVLA 408
Query: 682 GAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTG 861
GA K + +++ AG I+ E +IRTV SL + ++ LEV +
Sbjct: 409 GAVEMKLLTGHAVEDKKELEKAGKISTEAIENIRTVASLTREPKFESLYHENLEVPYKNS 468
Query: 862 IVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGG 1041
K G+ FS +Y +YA F +G+ LI + D +F V VL G+ ++G
Sbjct: 469 TKKAHVYGLTFAFSQAMIYFAYAGCFRFGAWLI-EEGRMDVQGVFLVISTVLYGAMAIGE 527
Query: 1042 ALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDI 1221
A ++ A+ +AS ++++IN P ID S EG D+ G++ F++V F YPSR D+
Sbjct: 528 ANSFTPNYAKAKMSASYLMQLINLEPAIDNLSQEGETPDSFDGNVHFENVRFNYPSRPDV 587
Query: 1222 HVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLR 1401
+L+G+ LE+K G+ +ALVGSSGCGKSTI+ LL+RFYDP +G V +D V+ + +N+H LR
Sbjct: 588 PILQGLDLEVKRGETLALVGSSGCGKSTIIQLLERFYDPREGSVALDNVNTKRLNIHWLR 647
Query: 1402 EQIGIVSQEPVLFDGTIYENIKMGNEH--ATHDQVVEACKMANANDFIKRLPDGYGTRVG 1575
Q+GIVSQEP LFD T+ +NI G+ AT D++V A K AN + FI+ LP+ Y T+ G
Sbjct: 648 SQMGIVSQEPTLFDCTLAQNIAYGDNSRIATMDEIVAAAKSANIHSFIQELPEKYDTQAG 707
Query: 1576 EKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRTTIIV 1755
+KG QLSGGQKQRIAIARA+++NP +LLLDEATSALDTE+E+ VQ ALDQA GRT IIV
Sbjct: 708 DKGTQLSGGQKQRIAIARAILRNPMLLLLDEATSALDTESEKVVQEALDQASKGRTCIIV 767
Query: 1756 AHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFY 1869
AHRLSTI+N DRI V + G +VE G+H++L++K+G+++
Sbjct: 768 AHRLSTIQNADRIAVLQGGVVVEQGTHQQLLAKRGVYH 805
>gi|7442650|pir||JG0166 LaMDR1 protein - Leishmania mexicana
amazonensis
Length = 1341
Score = 640 bits (1651), Expect = 0.0
Identities = 418/1233 (33%), Positives = 638/1233 (50%), Gaps = 25/1233 (2%)
Frame = +1
Query: 115 FYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGL 294
F Y D +L+I GT+ AV GAG PL + + G + T D + GV +V
Sbjct: 122 FRYADTADRVLMIIGTIFAVSCGAGMPLFSFIFGRIAT--------DLMSGVGSV----- 168
Query: 295 VPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQ 474
E N+ + Y+ +G MF + C+ A R ++R N+ +A+LRQ
Sbjct: 169 ------ELNAAKTSLIMVYVGIG--MFVACGGHVLCWIVAASRQEGRIRLNFFRAVLRQD 220
Query: 475 IQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMM 654
I W D+ G LTAR+T D + G+ DK + + A + GY GF +SW +TLVM+
Sbjct: 221 IGWHDEHSPGELTARMTGDTRVIHNGINDKLSQGIMNGAMGIIGYIAGFVFSWELTLVMV 280
Query: 655 GFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYN 834
G P I++ A + ++ T ++ +A AG++A E +IRTV EL RF
Sbjct: 281 GMMPFIIVMAAIIGNIVSKMTESSRKHFAKAGSMATEVMENIRTVQVFGREDYELQRFAE 340
Query: 835 ALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAV 1014
A+ ++ GI K + +Y SY +AF++GS L+ D I ++F AV
Sbjct: 341 AVLYAQERGIHKEFAGSLSAAVVMALVYLSYTVAFFFGSYLV-EWGRRDMADIISIFLAV 399
Query: 1015 LSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVH 1194
L GS LG P +F +R AA + + I P +D G+ V + I F +V
Sbjct: 400 LMGSFGLGFVAPSATAFTESRAAAYEIFKTIERVPPVD-IDAGGVPVTGFRQSIEFHNVR 458
Query: 1195 FRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDL 1374
F YP+R D+ + + ++L +K G K+A GSSGCGKS+++ L+QRFYDP G VL DGVD+
Sbjct: 459 FSYPTRPDMILFRDLNLTIKRGQKVAFSGSSGCGKSSMIGLIQRFYDPVGGAVLCDGVDM 518
Query: 1375 REVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPD 1554
RE+ ++ R+QIGIVSQEP LF G + EN+++G +AT ++V+EAC+ AN +D I LPD
Sbjct: 519 RELCLYDWRDQIGIVSQEPNLFAGIMMENVRVGKPNATEEEVIEACRQANVHDTIMSLPD 578
Query: 1555 GYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQ--A 1728
Y T VG G QLSGGQKQRIAIARALVK P ILLLDEATSALD ++E EVQ +LDQ
Sbjct: 579 QYNTPVGAVGSQLSGGQKQRIAIARALVKRPPILLLDEATSALDRKSEMEVQRSLDQLMQ 638
Query: 1729 QAGRTTIIVAHRLSTIRNVDRIFVFK-----AGNIVESGSHEELMSKQGIFYDMTXXXXX 1893
+ G I++AHRL TIRNVD I+ K I ESG+ +ELM+ G F M
Sbjct: 639 KGGMIVIVIAHRLETIRNVDCIYYMKYDGEEGSKITESGTFDELMALGGEFAAMARIQGV 698
Query: 1894 XXXXXEAG---------KDIEDTISESAHSHLXXXXXXXXXXXXXXXIHQLAEEVEECKA 2046
+G D+ + I + A + I +LA+ E
Sbjct: 699 SAGNARSGAKGQDDSKANDLLNVILDEA-TLAQLDEEAPRTARQKVPIEELAK--WEVNG 755
Query: 2047 PPTSMFKIFKFNGDKVGWXXXXXXXXXXXXSVTPVFALVYAEIFNV-----YSLPADQMQ 2211
++ N DK+ + P +++ + V ++ +Q++
Sbjct: 756 VNVGFGRLMGMNKDKLWAVALGILGSAVGGAARPTSSILMGYMLRVLGEYSFNKNVEQLR 815
Query: 2212 ANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRH 2391
+ + + +F++ + F+G+ G GE LT K+R F+ ++RQD+ F+D
Sbjct: 816 SGINLYAPLFIVFAVGNFLGWVLH-GFYGYAGEHLTTKIRLLLFRQIMRQDMNFFDIPGR 874
Query: 2392 GTGKLCTRFATDAPNVRYVF-TRLPVVLASIVTICGALGIGFYYGWQXXXXXXXXXXXXX 2568
G L + D V ++ + + + + I + + F Y W+
Sbjct: 875 DAGSLAGMLSGDCEAVHQLWGPSIGLKVQMVCIIAAGVVVSFIYQWKLALVALACMPLLI 934
Query: 2569 MGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFN 2748
E M + ++ + + + ++A+ +R V S N + + LR
Sbjct: 935 GCSLAERMMM--NRYTKSKDGDTSDTIVTEALSSVRIVTSFNMKADRVEAFEATLRVETP 992
Query: 2749 TNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIG 2928
+K G++ Q + + +A F+ GS +++ Q DV +I F Q G
Sbjct: 993 HGVKKGIIAGSINGARQFIHYGAFALCFWYGSKLIDRGEAQFTDVMIASMSILFGAQSTG 1052
Query: 2929 NTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITG-NISIRNVFFNYPTRKD 3105
+ +F + +A +A +F +I+ +D + SG G ++ R V F Y R
Sbjct: 1053 DAGAFATKLAEAERSAKRVFSVIDRVPDLD-IEQSGDKDLGKGCDVDFRKVQFIYSARPK 1111
Query: 3106 TKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSL 3285
VL L G T L+G +GCGKSTI+ +L RFY++ G+I ++G ++ +L+I+
Sbjct: 1112 QAVLASVNLRFGDGTTNGLIGQTGCGKSTIIQMLARFYDRRSGLICVNGKDLSSLDIAEW 1171
Query: 3286 REQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVG 3465
R + +V QEP LF T+ ENI Y + T +E+ EAA++A+IH I+ P GY+T VG
Sbjct: 1172 RRNISVVLQEPDLFSGTVRENIRY-AREDATDEEVEEAARLAHIHQEIMKWPGGYNTEVG 1230
Query: 3466 EKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDA--AKQGRTCL 3639
KG+ L GGQKQR+AIAR L+R P +LLLDEATSALD +E VQ+ ++A AK G T +
Sbjct: 1231 YKGSAL-GGQKQRVAIARGLLRRPKLLLLDEATSALDNVTEAKVQDGINAYQAKYGVTSV 1289
Query: 3640 VIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELI 3738
IAHRL+TI++ D I ++ G I+E+G+H+EL+
Sbjct: 1290 SIAHRLTTIRHCDQIILLDAGHIIEQGSHEELM 1322
Score = 298 bits (764), Expect = 5e-79
Identities = 201/578 (34%), Positives = 293/578 (49%), Gaps = 10/578 (1%)
Frame = +1
Query: 157 GTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEVVK 336
G + + + GA P +I++G M V +G + N ++++ S +
Sbjct: 777 GILGSAVGGAARPTSSILMGYMLRV----------LGEYSFNK------NVEQLRSGINL 820
Query: 337 YCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFD--KQQTGNL 510
Y ++V V F +V + E L K+R + I+RQ + +FD + G+L
Sbjct: 821 YAPLFIVFAVGNFL-GWVLHGFYGYAGEHLTTKIRLLLFRQIMRQDMNFFDIPGRDAGSL 879
Query: 511 TARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAK 690
L+ D E V + G L VQM AG V F Y W + LV + PL++ G
Sbjct: 880 AGMLSGDCEAVHQLWGPSIGLKVQMVCIIAAGVVVSFIYQWKLALVALACMPLLI--GCS 937
Query: 691 MSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVK 870
+++ M + + + I E SS+R V S N ++ F L V G+ K
Sbjct: 938 LAERMMMNRYTKSKDGDTSDTIVTEALSSVRIVTSFNMKADRVEAFEATLRVETPHGVKK 997
Query: 871 YCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGL-----IFTVFFAVLSGSTSL 1035
G G Y ++AL FWYGS LI DRG + ++L G+ S
Sbjct: 998 GIIAGSINGARQFIHYGAFALCFWYGSKLI------DRGEAQFTDVMIASMSILFGAQST 1051
Query: 1036 GGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKG-DISFKDVHFRYPSR 1212
G A A +A V VI+ P +D D KG D+ F+ V F Y +R
Sbjct: 1052 GDAGAFATKLAEAERSAKRVFSVIDRVPDLDIEQSGD--KDLGKGCDVDFRKVQFIYSAR 1109
Query: 1213 KDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVH 1392
VL ++L G L+G +GCGKSTI+ +L RFYD G + ++G DL +++
Sbjct: 1110 PKQAVLASVNLRFGDGTTNGLIGQTGCGKSTIIQMLARFYDRRSGLICVNGKDLSSLDIA 1169
Query: 1393 SLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRV 1572
R I +V QEP LF GT+ ENI+ E AT ++V EA ++A+ + I + P GY T V
Sbjct: 1170 EWRRNISVVLQEPDLFSGTVRENIRYAREDATDEEVEEAARLAHIHQEIMKWPGGYNTEV 1229
Query: 1573 GEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALD--QAQAGRTT 1746
G KG L GGQKQR+AIAR L++ PK+LLLDEATSALD E +VQ ++ QA+ G T+
Sbjct: 1230 GYKGSAL-GGQKQRVAIARGLLRRPKLLLLDEATSALDNVTEAKVQDGINAYQAKYGVTS 1288
Query: 1747 IIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQG 1860
+ +AHRL+TIR+ D+I + AG+I+E GSHEELM+ G
Sbjct: 1289 VSIAHRLTTIRHCDQIILLDAGHIIEQGSHEELMALGG 1326
>gi|38098857|gb|AAR11078.1| ATP binding cassette transporter
[Leptosphaeria maculans]
gi|46403062|gb|AAS92552.1| SirA [Leptosphaeria maculans]
Length = 1263
Score = 640 bits (1650), Expect = 0.0
Identities = 413/1254 (32%), Positives = 632/1254 (49%), Gaps = 32/1254 (2%)
Frame = +1
Query: 91 VKLTNYGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGV 270
+K+ + +F Y + LL+ A + GA FPLL + +G + V DF +G
Sbjct: 37 IKINYFSLFRYATVKEYALLLISAFFAAVSGAMFPLLILFIGNLVQVL-----KDFNLGT 91
Query: 271 DNVNPEGLVPISLDEFNSEVVKYCIY--YLVLGVLMFFTSYVQIACFESYAERLVHKLRQ 444
I ++ + ++ +Y YL LG L+ + C E + + +R+
Sbjct: 92 ----------IPQEQLSEQIRDIALYIVYLFLGQLVSVFIFTN-GCL-LVGEAITNAIRE 139
Query: 445 NYLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFF 624
Y++++ RQ I +FD +G +T++LT +++ + K L V + F+A Y +GF
Sbjct: 140 KYVRSLFRQNIAFFDTYGSGKITSQLTSSTATIQDAISHKIGLFVSACSCFVASYAIGFV 199
Query: 625 YSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNG 804
W +T ++ I MS MA A A A EETFS IR V +L
Sbjct: 200 KHWKLTFILTSTVVAITGVMIIMSGFMAKFGANSSGALAEASAKLEETFSGIRVVKALGL 259
Query: 805 HKR---ELD-RFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDP 972
KR ELD + N G++ V + I G ++ +Y LA W G +
Sbjct: 260 EKRLSDELDPQLLNIEFWGKRVRHVMGWMLAIMYGL----IFLNYGLAIWQGYRFM-QGG 314
Query: 973 TFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGIL 1152
T D G I TV + G+ G PHL + AA + VI D + G
Sbjct: 315 TEDVGAIITVLMCLNIGAFLFGNVGPHLQAMSLGAAAAQDIFAVIERESVTDGGAPPGSF 374
Query: 1153 VDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFY 1332
++G+I F++V YPSR D HVL+ S+ AG A+VG+SG GKSTIV++L+RFY
Sbjct: 375 --EVEGNIEFRNVSHVYPSRPDTHVLQDFSMIFPAGKVTAIVGASGSGKSTIVSILERFY 432
Query: 1333 DPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQ----- 1497
+P G+V +DG D+ +NV LR+Q G+V QEPVLF+G+I++N+ G + + Q
Sbjct: 433 EPVSGQVFLDGHDITHLNVQWLRQQFGLVGQEPVLFNGSIFKNVAYGLKGTQYGQESREV 492
Query: 1498 ----VVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLD 1665
V EAC++ANA+DFI LP GY VG +G LSGGQ+QRIAIARA+V PKILLLD
Sbjct: 493 TMKLVTEACRIANAHDFITALPHGYDQEVGIRGASLSGGQRQRIAIARAIVSGPKILLLD 552
Query: 1666 EATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEEL 1845
EATSALD ++E VQ L+ A +GRTTI+VAH LSTI+ D I V + G + + G+H EL
Sbjct: 553 EATSALDVQSEEAVQLGLNMASSGRTTIVVAHSLSTIKLADNIIVMEKGRVAQQGTHAEL 612
Query: 1846 MSKQGIFYDMTXXXXXXXXXXEAGKDIEDTISESAHSHLXXXXXXXXX-----XXXXXXI 2010
+++G++ + ++ E H+ + I
Sbjct: 613 EAQEGLYQTFVRR-----------QQLKQATLEPPHARITPAVDTPASPQHRLSEKTGSI 661
Query: 2011 HQLAEEVEECKAPPT--SMFKIFKF--NGDKVGWXXXXXXXXXXXXS--VTPVFALVYAE 2172
+ E K+P T S ++ KF +K W S V P ++ +A+
Sbjct: 662 YGQGESEAADKSPSTKYSFVQLVKFVARFNKEDWRLMVTGIASAVISGAVWPAHSVFFAK 721
Query: 2173 IFNVYSLPAD-QMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKN 2349
S P+ + FW M+V++ + C E L ++ R AFK
Sbjct: 722 AIVALSSPSPASLARGPNFWAAMYVMLAFVQIASQGVQGSAFAICAERLILRARRVAFKY 781
Query: 2350 LLRQDIAFYDDLRHGTGKLCTRFATDA---PNVRYVFTRLPVVLASIVTICGALGIGFYY 2520
LLRQD+ F+DD H +G + + ++D + VF L + ++ T+ G L +
Sbjct: 782 LLRQDVEFFDDPLHSSGIMTSFVSSDVNALAGLSGVF--LGTLFSATATVLGGLILSLAV 839
Query: 2521 GWQXXXXXXXXXXXXXMGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNRQ 2700
GW+ + GY +++ + ++ EE+ + + +RTV + +
Sbjct: 840 GWKLTLVTMGTIPIIIVAGYVRLKLVGTLEKISRKVHEESAGRVCEEINAVRTVAASCLE 899
Query: 2701 EQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPID 2880
++ Y L+ T L+ +A S+++ + F+ G+ V +
Sbjct: 900 DEMCEDYVRSLKSKEKTYLRATLWSSGWYALSEAVPLGCMSLGFWYGATLVMRTEYTTEQ 959
Query: 2881 VYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSG-IVKPITG 3057
+ V A+ F G +F PD KA ++A L L++ +D+ S+ G ++ G
Sbjct: 960 FFIVVTAVIFGASSAGLVFAFAPDFGKAGVSAERLQELVDRQPEVDTWSEEGDHIETTNG 1019
Query: 3058 NISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGM 3237
+ + NV F Y R T VL +L G+++ L G SG GKST+ LLERFYN G
Sbjct: 1020 KVDVSNVVFYYNQRSKTPVLNSISLGAAPGQSIGLCGGSGSGKSTVASLLERFYNPSSGT 1079
Query: 3238 IMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGT-NRNVTYQEIVEAAKMAN 3414
+ +D ++R +NI+S R Q +V+QEP LF C+I EN+ YG+ +++T EI EA KMA
Sbjct: 1080 VSLDEKDVRTININSYRAQFALVNQEPLLFSCSIRENLLYGSLGKDLTDSEIEEACKMAQ 1139
Query: 3415 IHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKI 3594
+++F+ LP+G DT G LSGGQ+QR++IARA++R P VL+LDEATSALD+ SE+
Sbjct: 1140 VYDFVCSLPEGLDTSFGSNAVMLSGGQRQRLSIARAILRKPRVLILDEATSALDSTSERA 1199
Query: 3595 VQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEIY 3756
V EAL +GRT +++AHRLSTIQ D I + G + E+GTH+EL+ K Y
Sbjct: 1200 VIEALTKTAEGRTTIMVAHRLSTIQGCDKIFYLRAGAVAEEGTHEELMAKRGSY 1253
Score = 322 bits (826), Expect = 3e-86
Identities = 196/583 (33%), Positives = 313/583 (53%), Gaps = 4/583 (0%)
Frame = +1
Query: 136 DLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDE 315
D L++TG +AVI GA +P ++ F +A +V + + +P L
Sbjct: 694 DWRLMVTGIASAVISGAVWPAHSVF-------FAKA-----IVALSSPSPASLA------ 735
Query: 316 FNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDK- 492
+ Y++L + + VQ + F AERL+ + R+ K +LRQ +++FD
Sbjct: 736 --RGPNFWAAMYVMLAFVQIASQGVQGSAFAICAERLILRARRVAFKYLLRQDVEFFDDP 793
Query: 493 -QQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPL 669
+G +T+ ++ D+ + G L A L G + W +TLV MG P+
Sbjct: 794 LHSSGIMTSFVSSDVNALAGLSGVFLGTLFSATATVLGGLILSLAVGWKLTLVTMGTIPI 853
Query: 670 IVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVG 849
I+++G K + T ++ ++ + + E +++RTV + + + +L+
Sbjct: 854 IIVAGYVRLKLVGTLEKISRKVHEESAGRVCEEINAVRTVAASCLEDEMCEDYVRSLKSK 913
Query: 850 RQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGST 1029
+T + + S +L FWYG+TL++ + F V AV+ G++
Sbjct: 914 EKTYLRATLWSSGWYALSEAVPLGCMSLGFWYGATLVMRTE-YTTEQFFIVVTAVIFGAS 972
Query: 1030 SLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPS 1209
S G FG A +A + +++ P++D +S EG ++ G + +V F Y
Sbjct: 973 SAGLVFAFAPDFGKAGVSAERLQELVDRQPEVDTWSEEGDHIETTNGKVDVSNVVFYYNQ 1032
Query: 1210 RKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNV 1389
R VL ISL G I L G SG GKST+ +LL+RFY+P+ G V +D D+R +N+
Sbjct: 1033 RSKTPVLNSISLGAAPGQSIGLCGGSGSGKSTVASLLERFYNPSSGTVSLDEKDVRTINI 1092
Query: 1390 HSLREQIGIVSQEPVLFDGTIYENIKMGN--EHATHDQVVEACKMANANDFIKRLPDGYG 1563
+S R Q +V+QEP+LF +I EN+ G+ + T ++ EACKMA DF+ LP+G
Sbjct: 1093 NSYRAQFALVNQEPLLFSCSIRENLLYGSLGKDLTDSEIEEACKMAQVYDFVCSLPEGLD 1152
Query: 1564 TRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQAGRT 1743
T G V LSGGQ+QR++IARA+++ P++L+LDEATSALD+ +ER V AL + GRT
Sbjct: 1153 TSFGSNAVMLSGGQRQRLSIARAILRKPRVLILDEATSALDSTSERAVIEALTKTAEGRT 1212
Query: 1744 TIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEELMSKQGIFYD 1872
TI+VAHRLSTI+ D+IF +AG + E G+HEELM+K+G +YD
Sbjct: 1213 TIMVAHRLSTIQGCDKIFYLRAGAVAEEGTHEELMAKRGSYYD 1255
Score = 288 bits (737), Expect = 7e-76
Identities = 182/553 (32%), Positives = 286/553 (50%), Gaps = 14/553 (2%)
Frame = +1
Query: 2176 FNVYSLPADQMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLL 2355
FN+ ++P +Q+ + V + + V F N GE++T +R + ++L
Sbjct: 87 FNLGTIPQEQLSEQIRDIALYIVYLFLGQLVSVFIFTNGCLLVGEAITNAIREKYVRSLF 146
Query: 2356 RQDIAFYDDLRHGTGKLCTRFATDAPNVRYVFT-RLPVVLASIVTICGALGIGFYYGWQX 2532
RQ+IAF+D +G+GK+ ++ + ++ + ++ + +++ + IGF W+
Sbjct: 147 RQNIAFFDT--YGSGKITSQLTSSTATIQDAISHKIGLFVSACSCFVASYAIGFVKHWKL 204
Query: 2533 XXXXXXXXXXXX-----MGGYFEMQMRFGKQIRDTQLLEEAGKVASQAVEHIRTVHSLNR 2697
M G+ +FG + L EA + IR V +L
Sbjct: 205 TFILTSTVVAITGVMIIMSGFMA---KFGAN--SSGALAEASAKLEETFSGIRVVKALGL 259
Query: 2698 QEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPI 2877
+++ L + H G + A LIF Y A + G F+
Sbjct: 260 EKRLSDELDPQLLNIEFWGKRVRHVMGWMLAIMYGLIFLNYGLAIWQGYRFMQGGTEDVG 319
Query: 2878 DVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITG 3057
+ V ++ + GN + + AA +F +IE + D + G + + G
Sbjct: 320 AIITVLMCLNIGAFLFGNVGPHLQAMSLGAAAAQDIFAVIERESVTDGGAPPGSFE-VEG 378
Query: 3058 NISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGM 3237
NI RNV YP+R DT VLQ F++ AGK A+VG SG GKSTI+ +LERFY G
Sbjct: 379 NIEFRNVSHVYPSRPDTHVLQDFSMIFPAGKVTAIVGASGSGKSTIVSILERFYEPVSGQ 438
Query: 3238 IMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGT--------NRNVTYQEIV 3393
+ +DG +I +LN+ LR+Q +V QEP LF+ +I +N+ YG +R VT + +
Sbjct: 439 VFLDGHDITHLNVQWLRQQFGLVGQEPVLFNGSIFKNVAYGLKGTQYGQESREVTMKLVT 498
Query: 3394 EAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSAL 3573
EA ++AN H+FI LP GYD VG +G LSGGQ+QRIAIARA+V P +LLLDEATSAL
Sbjct: 499 EACRIANAHDFITALPHGYDQEVGIRGASLSGGQRQRIAIARAIVSGPKILLLDEATSAL 558
Query: 3574 DTESEKIVQEALDAAKQGRTCLVIAHRLSTIQNSDVIAIVSEGKIVEKGTHDELIRKSEI 3753
D +SE+ VQ L+ A GRT +V+AH LSTI+ +D I ++ +G++ ++GTH EL + +
Sbjct: 559 DVQSEEAVQLGLNMASSGRTTIVVAHSLSTIKLADNIIVMEKGRVAQQGTHAELEAQEGL 618
Query: 3754 YQKFCETQRIVES 3792
YQ F Q++ ++
Sbjct: 619 YQTFVRRQQLKQA 631