Homology by BLASTX


BLASTX 2.2.4 [Aug-26-2002]
Query= F20B6_1
         (4266 letters)

Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
           1,967,186 sequences; 661,712,633 total letters


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|17567189|ref|NP_508710.1| multidrug Resistance Protein (mrp-6...  2614   0.0
gi|30794620|gb|AAA82317.2| Multidrug resistance protein family p...  2564   0.0
gi|39597842|emb|CAE68534.1| Hypothetical protein CBG14361 [Caeno...   780   0.0
gi|26984454|emb|CAD24440.2| SI:dZ52I16.4 (novel ABC transporter ...   696   0.0
gi|31322321|gb|AAO37649.1| ATP-binding cassette transporter C4 [...   684   0.0
gi|5031915|ref|NP_005836.1| ATP-binding cassette, sub-family C, ...   683   0.0
gi|21655123|gb|AAL88745.1| multidrug resistance-associated prote...   681   0.0
gi|45862332|gb|AAS78928.1| multidrug resistance-associated prote...   679   0.0
gi|28480852|ref|XP_139262.2| similar to ATP-binding cassette tra...   677   0.0
gi|45862334|gb|AAS78929.1| multidrug resistance-associated prote...   677   0.0
gi|23305895|gb|AAN17334.1| ATP-binding cassette protein C4 splic...   658   0.0
gi|24648279|ref|NP_650838.1| CG4562-PA [Drosophila melanogaster]...   654   0.0
gi|24582795|ref|NP_609215.2| CG7627-PA [Drosophila melanogaster]...   647   0.0
gi|28574259|ref|NP_609930.4| CG31793-PA [Drosophila melanogaster...   636   e-180
gi|24649703|ref|NP_651269.1| CG5789-PA [Drosophila melanogaster]...   622   e-176
gi|27374383|gb|AAO01121.1| CG4562-PA [Drosophila pseudoobscura]       620   e-176
gi|13559039|emb|CAC36037.1| bA464I2.1 (ATP-binding cassette, sub...   619   e-175
gi|24585091|ref|NP_724148.1| CG31792-PA [Drosophila melanogaster...   617   e-175
gi|31207927|ref|XP_312930.1| ENSANGP00000014021 [Anopheles gambi...   614   e-174
gi|47216708|emb|CAG00982.1| unnamed protein product [Tetraodon n...   605   e-171
gi|21358185|ref|NP_651678.1| CG11897-PB [Drosophila melanogaster...   605   e-171
gi|45550390|ref|NP_610482.2| CG8799-PA [Drosophila melanogaster]...   600   e-170
gi|24656876|ref|NP_611571.1| CG10505-PA [Drosophila melanogaster...   565   e-159
gi|3335175|gb|AAC27077.1| ABC transporter MOAT-B isoform [Homo s...   557   e-157
gi|15292027|gb|AAK93282.1| LD35689p [Drosophila melanogaster]         555   e-156
gi|31241739|ref|XP_321300.1| ENSANGP00000008456 [Anopheles gambi...   552   e-155
gi|16758936|ref|NP_446376.1| ATP-binding cassette, sub-family C ...   545   e-153
gi|50752361|ref|XP_422754.1| PREDICTED: similar to Multidrug res...   543   e-152
gi|7304851|ref|NP_038818.1| ATP-binding cassette, sub-family C, ...   540   e-152
gi|21356615|ref|NP_650086.1| CG14709-PA [Drosophila melanogaster...   538   e-151
gi|31542029|ref|NP_071617.2| ATP-binding cassette, sub-family C ...   538   e-151
gi|29468521|gb|AAO44983.1| ATP-binding cassette protein C1 varia...   537   e-150
gi|8928547|sp|O15440|MRP5_HUMAN Multidrug resistance-associated ...   536   e-150
gi|31217619|ref|XP_316463.1| ENSANGP00000004277 [Anopheles gambi...   536   e-150
gi|5006891|gb|AAD37716.1| ABC protein [Homo sapiens]                  536   e-150
gi|27357193|gb|AAN86532.1| multidrug resistance-associated prote...   535   e-150
gi|5032101|ref|NP_005679.1| ATP-binding cassette, sub-family C, ...   535   e-150
gi|4587083|dbj|BAA76608.1| MRP5 [Homo sapiens]                        533   e-149
gi|29893528|gb|AAN65348.1| multidrug resistance protein 1A [Maca...   532   e-149
gi|29893530|gb|AAN65349.1| multidrug resistance protein 1B [Maca...   531   e-149
gi|24585557|ref|NP_610079.2| CG9270-PA [Drosophila melanogaster]...   531   e-149
gi|45552437|ref|NP_995741.1| CG9270-PB [Drosophila melanogaster]...   531   e-149
gi|33589528|gb|AAQ22531.1| LD15381p [Drosophila melanogaster]         530   e-149
gi|17863020|gb|AAL39987.1| SD08921p [Drosophila melanogaster]         526   e-147
gi|20892039|ref|XP_147225.1| ATP-binding cassette, sub-family C,...   521   e-146
gi|40786453|ref|NP_955409.1| ATP-binding cassette protein C12; A...   521   e-146
gi|47226181|emb|CAG08328.1| unnamed protein product [Tetraodon n...   519   e-145
gi|48097312|ref|XP_393750.1| similar to ENSANGP00000004277 [Apis...   518   e-145
gi|30315152|gb|AAP30800.1| ATP-binding cassette protein C12 [Mus...   518   e-145
gi|24650989|ref|NP_651679.1| CG11898-PA [Drosophila melanogaster...   511   e-143
gi|50311901|ref|XP_455982.1| unnamed protein product [Kluyveromy...   510   e-142
gi|31212473|ref|XP_315221.1| ENSANGP00000001450 [Anopheles gambi...   506   e-141
gi|48143003|ref|XP_397395.1| similar to ENSANGP00000004277 [Apis...   503   e-140
gi|37778161|gb|AAO74587.1| ATP-binding cassette protein C12 vari...   501   e-140
gi|48095613|ref|XP_394490.1| similar to CG7806-PA [Apis mellifera]    491   e-137
gi|7428837|pir||JC5667 multidrug resistance protein, short type ...   490   e-136
gi|30313820|gb|AAO49801.1| ATP-binding cassette C5 splicing vari...   489   e-136
gi|50286809|ref|XP_445834.1| unnamed protein product [Candida gl...   481   e-134
gi|19172026|gb|AAL85705.1| ABC transporter ABCC.2 [Dictyostelium...   479   e-133
gi|8134577|sp|Q28689|MRP2_RABIT Canalicular multispecific organi...   478   e-133
gi|19172042|gb|AAL85713.1| ABC transporter ABCC.10 [Dictyosteliu...   478   e-133
gi|49071788|ref|XP_400183.1| hypothetical protein UM02568.1 [Ust...   477   e-132
gi|27368875|emb|CAD59595.1| MRP-like ABC transporter [Oryza sati...   474   e-131
gi|19172028|gb|AAL85706.1| ABC transporter ABCC.3 [Dictyostelium...   473   e-131
gi|45552349|ref|NP_995697.1| CG6214-PE [Drosophila melanogaster]...   473   e-131
gi|45552361|ref|NP_995703.1| CG6214-PN [Drosophila melanogaster]...   473   e-131
gi|38346945|emb|CAE04806.2| OSJNBb0022P19.1 [Oryza sativa (japon...   473   e-131
gi|45552347|ref|NP_995696.1| CG6214-PF [Drosophila melanogaster]...   472   e-131
gi|45552337|ref|NP_995691.1| CG6214-PK [Drosophila melanogaster]...   472   e-131
gi|50402226|sp|Q8VI47|MRP2_MOUSE Canalicular multispecific organ...   472   e-131
gi|17224462|gb|AAL36986.1| sub-family C member 2 ATP-binding cas...   472   e-131
gi|45552351|ref|NP_995698.1| CG6214-PD [Drosophila melanogaster]...   471   e-131
gi|45552339|ref|NP_995692.1| CG6214-PJ [Drosophila melanogaster]...   471   e-131
gi|1574998|gb|AAB09422.1| canalicular multispecific organic anio...   471   e-131
gi|6978669|ref|NP_036965.1| ATP-binding cassette, sub-family C (...   471   e-131
gi|1405353|dbj|BAA13016.1| canalicular multispecific organic ani...   471   e-131
gi|32127554|emb|CAD98883.1| ABC protein [Phanerochaete chrysospo...   469   e-130
gi|4557481|ref|NP_000383.1| ATP-binding cassette, sub-family C (...   469   e-130
gi|11184219|ref|NP_038834.1| ATP-binding cassette, sub-family C,...   469   e-130
gi|31233793|ref|XP_318949.1| ENSANGP00000015753 [Anopheles gambi...   468   e-130
gi|45552343|ref|NP_995694.1| CG6214-PH [Drosophila melanogaster]...   468   e-130
gi|45552363|ref|NP_995704.1| CG6214-PM [Drosophila melanogaster]...   468   e-130
gi|2135769|pir||S71841 multidrug resistance protein, canalicular...   467   e-130
gi|5107947|emb|CAB45309.1| multidrug resistance protein 2 (MRP2)...   467   e-130
gi|15100172|ref|NP_150229.1| ATP-binding cassette, sub-family C,...   467   e-130
gi|50257043|gb|EAL19761.1| hypothetical protein CNBG3890 [Crypto...   467   e-129
gi|24583969|ref|NP_609591.2| CG6214-PB [Drosophila melanogaster]...   466   e-129
gi|45552353|ref|NP_995699.1| CG6214-PC [Drosophila melanogaster]...   466   e-129
gi|17862990|gb|AAL39972.1| SD07655p [Drosophila melanogaster]         466   e-129
gi|45552341|ref|NP_995693.1| CG6214-PI [Drosophila melanogaster]...   465   e-129
gi|45550972|ref|NP_723772.2| CG6214-PA [Drosophila melanogaster]...   465   e-129
gi|19172030|gb|AAL85707.1| ABC transporter ABCC.4 [Dictyostelium...   464   e-128
gi|15593234|gb|AAL02216.1| multidrug resistance protein MRP2 [Ma...   463   e-128
gi|45552335|ref|NP_995690.1| CG6214-PL [Drosophila melanogaster]...   463   e-128
gi|45552345|ref|NP_995695.1| CG6214-PG [Drosophila melanogaster]...   463   e-128
gi|15130910|emb|CAC48162.1| multidrug resistance protein 2 [Cani...   463   e-128
gi|46394980|gb|AAS91646.1| multidrug resistance protein 2; MRP2 ...   461   e-128
gi|14280091|gb|AAK58869.1| ATP-binding cassette protein C11 [Hom...   461   e-128
gi|15149474|ref|NP_149163.2| ATP-binding cassette, sub-family C,...   461   e-128
gi|19172046|gb|AAL85715.1| ABC transporter ABCC.12 [Dictyosteliu...   461   e-128
gi|27368873|emb|CAD59594.1| MRP-like ABC transporter [Oryza sati...   461   e-128
gi|49098240|ref|XP_410580.1| hypothetical protein AN6443.2 [Aspe...   460   e-127
gi|13346481|gb|AAK19755.1| ATP-binding cassette transporter MRP8...   459   e-127
gi|41053579|ref|NP_956883.1| similar to multidrug resistance pro...   459   e-127
gi|45552357|ref|NP_995701.1| CG6214-PP [Drosophila melanogaster]...   458   e-127
gi|45552355|ref|NP_995700.1| CG6214-PQ [Drosophila melanogaster]...   458   e-127
gi|50745417|ref|XP_420102.1| PREDICTED: similar to Canalicular m...   458   e-127
gi|7428836|pir||DVHUAR multidrug resistance protein (cell line H...   458   e-127
gi|27368881|emb|CAD59598.1| MRP-like ABC transporter [Oryza sati...   457   e-126
gi|25297465|pir||T52081 MRP-like ABC transporter [imported] - Ar...   456   e-126
gi|556465|gb|AAA50353.1| metal resistance protein                     456   e-126
gi|2585772|gb|AAB83979.1| multidrug resistance protein [Homo sap...   456   e-126
gi|6320339|ref|NP_010419.1| Vacuolar glutathione S-conjugate tra...   456   e-126
gi|9955960|ref|NP_063957.1| ATP-binding cassette, sub-family C, ...   456   e-126
gi|9955958|ref|NP_063956.1| ATP-binding cassette, sub-family C, ...   456   e-126
gi|50293283|ref|XP_449053.1| unnamed protein product [Candida gl...   456   e-126
gi|4826838|ref|NP_004987.1| ATP-binding cassette, sub-family C, ...   456   e-126
gi|48142909|ref|XP_397384.1| similar to Multidrug resistance-ass...   455   e-126
gi|19172036|gb|AAL85710.1| ABC transporter ABCC.7 [Dictyostelium...   454   e-126
gi|19172024|gb|AAL85704.1| ABC transporter ABCC.1 [Dictyostelium...   453   e-125
gi|49069514|ref|XP_399046.1| hypothetical protein UM01431.1 [Ust...   452   e-125
gi|46437884|gb|EAK97223.1| hypothetical protein CaO19.6382 [Cand...   452   e-125
gi|46437795|gb|EAK97135.1| hypothetical protein CaO19.13739 [Can...   452   e-125
gi|27806339|ref|NP_776648.1| ATP-binding cassette, sub-family C ...   451   e-125
gi|33621129|gb|AAQ23148.1| multidrug resistance-associated prote...   450   e-124
gi|6678848|ref|NP_032602.1| ATP-binding cassette, sub-family C, ...   450   e-124
gi|15230686|ref|NP_187915.1| ABC transporter family protein [Ara...   450   e-124
gi|8843832|dbj|BAA97256.1| sulphonylurea receptor 2b [Rattus nor...   449   e-124
gi|34910256|ref|NP_916475.1| putative MRP-like ABC transporter [...   449   e-124
gi|42733544|dbj|BAD11207.1| multidrug resistance-associated prot...   449   e-124
gi|30682486|ref|NP_187917.3| ABC transporter family protein [Ara...   448   e-124
gi|50551495|ref|XP_503221.1| hypothetical protein [Yarrowia lipo...   448   e-124
gi|39585277|emb|CAE57520.1| Hypothetical protein CBG00495 [Caeno...   448   e-124
gi|50553943|ref|XP_504380.1| hypothetical protein [Yarrowia lipo...   447   e-124
gi|22759566|emb|CAD45086.1| multidrug-resistance related protein...   447   e-123
gi|18034783|ref|NP_542148.1| ATP-binding cassette, sub-family C ...   447   e-123
gi|19111847|ref|NP_595055.1| ABC multidrug or ion efflux transpo...   447   e-123
gi|29179622|gb|AAH48825.1| Similar to ATP-binding cassette, sub-...   446   e-123
gi|19923678|ref|NP_037172.2| ATP-binding cassette, sub-family C ...   446   e-123
gi|6755696|ref|NP_035641.1| ATP-binding cassette, sub-family C, ...   446   e-123
gi|50545229|ref|XP_500152.1| hypothetical protein [Yarrowia lipo...   446   e-123
gi|39583704|emb|CAE63808.1| Hypothetical protein CBG08354 [Caeno...   445   e-123
gi|6016599|sp|O88563|MRP3_RAT Canalicular multispecific organic ...   444   e-123
gi|17556528|ref|NP_499598.1| multidrug Resistance Protein (mrp-8...   443   e-122
gi|15226801|ref|NP_181013.1| glutathione S-conjugate ABC transpo...   442   e-122
gi|2909781|gb|AAC04245.1| MgATP-energized glutathione S-conjugat...   442   e-122
gi|32405776|ref|XP_323501.1| related to ATP-binding cassette tra...   441   e-122
gi|46122387|ref|XP_385747.1| hypothetical protein FG05571.1 [Gib...   441   e-122
gi|50422977|ref|XP_460066.1| unnamed protein product [Debaryomyc...   441   e-122
gi|50553953|ref|XP_504385.1| hypothetical protein [Yarrowia lipo...   441   e-122
gi|18202598|sp|Q63563|ACC9_RAT Sulfonylurea receptor 2 >gnl|BL_O...   440   e-121
gi|7209305|dbj|BAA92227.1| FLJ00002 protein [Homo sapiens]            440   e-121
gi|25914749|ref|NP_258261.2| ATP-binding cassette, sub-family C,...   440   e-121
gi|2440015|gb|AAC49988.1| multidrug resistance-associated protei...   440   e-121
gi|46442694|gb|EAL01981.1| hypothetical protein CaO19.13832 [Can...   440   e-121
gi|15220735|ref|NP_174329.1| glutathione S-conjugate ABC transpo...   439   e-121
gi|19569597|gb|AAL92112.1| multidrug resistance-associated prote...   439   e-121
gi|9188172|emb|CAB97204.1| conjugate export pump protein [Rattus...   439   e-121
gi|11557970|emb|CAC17701.1| multidrug resistance protein 2 [Cani...   439   e-121
gi|11038664|ref|NP_066378.1| ATP-binding cassette, sub-family C,...   438   e-121
gi|11038668|ref|NP_066380.1| ATP-binding cassette, sub-family C,...   438   e-121
gi|19172032|gb|AAL85708.1| ABC transporter ABCC.5 [Dictyostelium...   438   e-121
gi|37694082|gb|AAO72317.1| multidrug resistance associated prote...   438   e-121
gi|30682479|ref|NP_187916.3| ABC transporter, putative [Arabidop...   438   e-121
gi|18031899|gb|AAL14776.1| ATP-binding cassette transporter MRP6...   438   e-121
gi|49068076|ref|XP_398327.1| hypothetical protein UM00712.1 [Ust...   437   e-121
gi|50755781|ref|XP_414899.1| PREDICTED: similar to ATP-binding c...   437   e-120
gi|33329359|gb|AAQ10074.1| multidrug resistance associated prote...   436   e-120
gi|33517380|gb|AAQ19996.1| ATP-binding cassette transporter 13 [...   436   e-120
gi|2340166|gb|AAB67319.1| glutathione S-conjugate transporting A...   436   e-120
gi|50749655|ref|XP_421698.1| PREDICTED: similar to canalicular m...   435   e-120
gi|2909783|gb|AAC04246.1| MgATP-energized glutathione S-conjugat...   435   e-120
gi|6634763|gb|AAF19743.1| Similar to gb|AF008124 Arabidopsis tha...   433   e-119
gi|38111834|gb|EAA57340.1| hypothetical protein MG08309.4 [Magna...   432   e-119
gi|15220745|ref|NP_174330.1| ATP-binding cassette transport prot...   432   e-119
gi|27368877|emb|CAD59596.1| MRP-like ABC transporter [Oryza sati...   432   e-119
gi|27263148|emb|CAD59448.1| MRP-like ABC transporter [Oryza sati...   432   e-119
gi|38344335|emb|CAD41751.2| OSJNBa0058K23.17 [Oryza sativa (japo...   432   e-119
gi|50285781|ref|XP_445319.1| unnamed protein product [Candida gl...   432   e-119
gi|21103955|gb|AAK39642.1| multidrug resistance-associated prote...   431   e-118
gi|15227133|ref|NP_182301.1| glutathione-conjugate transporter (...   430   e-118
gi|47228841|emb|CAG09356.1| unnamed protein product [Tetraodon n...   429   e-118
gi|39579782|emb|CAE56020.1| Hypothetical protein CBG23578 [Caeno...   429   e-118
gi|9955970|ref|NP_003777.2| ATP-binding cassette, sub-family C, ...   428   e-118
gi|4826563|emb|CAA76658.2| multidrug resistance protein 3 (ABCC3...   428   e-118
gi|3132270|dbj|BAA28146.1| multidrug resistance-associated prote...   428   e-118
gi|39596661|emb|CAE63280.1| Hypothetical protein CBG07659 [Caeno...   428   e-118
gi|4102188|gb|AAD01430.1| MRP3 [Homo sapiens]                         428   e-118
gi|17569081|ref|NP_508121.1| multidrug Resistance Protein, ABC t...   427   e-118
gi|7442652|pir||JE0336 canalicular multispecific organic anion t...   427   e-118
gi|19114855|ref|NP_593943.1| ABC multidrug or ion efflux transpo...   427   e-117
gi|19172034|gb|AAL85709.1| ABC transporter ABCC.6 [Dictyostelium...   427   e-117
gi|17551700|ref|NP_510479.1| multidrug Resistance Protein (158.6...   427   e-117
gi|50259319|gb|EAL21992.1| hypothetical protein CNBC1320 [Crypto...   426   e-117
gi|1518137|gb|AAB07022.1| multidrug resistance related protein 2      424   e-117
gi|39592570|emb|CAE63647.1| Hypothetical protein CBG08145 [Caeno...   424   e-117
gi|19172040|gb|AAL85712.1| ABC transporter ABCC.9 [Dictyostelium...   424   e-117
gi|17567243|ref|NP_509658.1| multidrug Resistance Protein (mrp-4...   424   e-117
gi|46275862|gb|AAS86407.1| putative MRP-like ABC transporter [Or...   422   e-116
gi|15220748|ref|NP_174331.1| ATP-binding cassette transport prot...   422   e-116
gi|34874450|ref|XP_236930.2| similar to multidrug resistance-ass...   422   e-116
gi|42568992|ref|NP_178811.3| ABC transporter family protein [Ara...   421   e-116
gi|15718604|gb|AAL06032.1| Multidrug resistance protein family p...   421   e-116
gi|15219648|ref|NP_171908.1| ABC transporter family protein [Ara...   421   e-116
gi|7485868|pir||T00961 hypothetical protein F20D22.11 - Arabidop...   421   e-116
gi|27368883|emb|CAD59599.1| MRP-like ABC transporter [Oryza sati...   421   e-116
gi|45201142|ref|NP_986712.1| AGR047Wp [Eremothecium gossypii] >g...   421   e-116
gi|47847932|dbj|BAD21722.1| putative MRP-like ABC transporter [O...   421   e-116
gi|31241741|ref|XP_321301.1| ENSANGP00000008459 [Anopheles gambi...   421   e-115
gi|38346704|emb|CAE04854.2| OSJNBa0086O06.2 [Oryza sativa (japon...   420   e-115
gi|45200751|ref|NP_986321.1| AGL346Wp [Eremothecium gossypii] >g...   420   e-115
gi|50287891|ref|XP_446375.1| unnamed protein product [Candida gl...   419   e-115
gi|39592571|emb|CAE63648.1| Hypothetical protein CBG08146 [Caeno...   419   e-115
gi|26339846|dbj|BAC33586.1| unnamed protein product [Mus musculus]    418   e-115
gi|15228832|ref|NP_191829.1| glutathione-conjugate transporter, ...   418   e-115
gi|7428835|pir||DVLNS multidrug resistance protein - Leishmania ...   418   e-115
gi|25297466|pir||E89447 protein F57C12.4 [imported] - Caenorhabd...   418   e-115
gi|1170904|sp|P21441|MDR_LEITA Multidrug resistance protein (P-g...   417   e-115
gi|32421921|ref|XP_331404.1| hypothetical protein [Neurospora cr...   417   e-115
gi|39596086|emb|CAE69722.1| Hypothetical protein CBG15993 [Caeno...   416   e-114
gi|10172596|dbj|BAB01400.1| multidrug resistance-associated prot...   416   e-114
gi|50306541|ref|XP_453244.1| unnamed protein product [Kluyveromy...   415   e-114
gi|34907722|ref|NP_915208.1| putative MRP-like ABC transporter [...   415   e-114
gi|24850123|ref|NP_733780.1| ATP-binding cassette, sub-family C,...   415   e-114
gi|21553091|ref|NP_660122.1| ATP-binding cassette, sub-family C,...   415   e-114
gi|39590950|emb|CAE58730.1| Hypothetical protein CBG01916 [Caeno...   414   e-114
gi|49112201|ref|XP_411866.1| hypothetical protein AN7729.2 [Aspe...   414   e-113
gi|50404890|ref|YP_053982.1| Multispecific organic anion transpo...   413   e-113
gi|50411234|ref|XP_457028.1| unnamed protein product [Debaryomyc...   413   e-113
gi|6323014|ref|NP_013086.1| ABC type transmembrane transporter o...   413   e-113
gi|19851882|gb|AAL99902.1| ATP-binding cassette protein C11 isof...   413   e-113
gi|21729876|ref|NP_660187.1| ATP-binding cassette, sub-family C,...   413   e-113
gi|27368879|emb|CAD59597.1| MRP-like ABC transporter [Oryza sati...   412   e-113
gi|37694078|gb|AAO72315.1| multidrug resistance associated prote...   412   e-113
gi|6321720|ref|NP_011797.1| Plasma membrane transporter of the A...   412   e-113
gi|21629500|gb|AAM69107.1| Multidrug resistance protein family p...   410   e-112
gi|15232264|ref|NP_191575.1| ABC transporter family protein [Ara...   410   e-112
gi|17568267|ref|NP_508122.1| multidrug Resistance Protein, ABC t...   410   e-112
gi|49084304|ref|XP_404362.1| hypothetical protein AN0225.2 [Aspe...   410   e-112
gi|50420901|ref|XP_458993.1| unnamed protein product [Debaryomyc...   409   e-112
gi|15559191|emb|CAC69553.1| multidrug resistance associated prot...   409   e-112
gi|25411318|pir||F84487 probable ABC transporter [imported] - Ar...   408   e-112
gi|6321752|ref|NP_011828.1| Protein of unknown function, member ...   405   e-111
gi|1518135|gb|AAB07021.1| multidrug resistance related protein 1      405   e-111
gi|1711613|sp|Q09427|ACC8_CRICR Sulfonylurea receptor 1 >gnl|BL_...   405   e-111
gi|46132976|ref|XP_389193.1| hypothetical protein FG09017.1 [Gib...   403   e-110
gi|47717725|gb|AAT37905.1| multidrug-resistance associated prote...   402   e-110
gi|50548977|ref|XP_501959.1| hypothetical protein [Yarrowia lipo...   402   e-110
gi|46439278|gb|EAK98598.1| hypothetical protein CaO19.12566 [Can...   401   e-110
gi|19549337|gb|AAD51594.2| MRP-like transporter [Candida albicans]    400   e-109
gi|9955950|ref|NP_063915.1| ATP-binding cassette, sub-family C, ...   400   e-109
gi|10947122|ref|NP_064693.1| ATP-binding cassette, sub-family C,...   400   e-109
gi|2585774|gb|AAB83981.1| multidrug resistance protein [Homo sap...   400   e-109
gi|15233000|ref|NP_191656.1| ABC transporter family protein [Ara...   399   e-109
gi|37650995|emb|CAD54072.1| sulphonylurea receptor 1 [Rattus nor...   399   e-109
gi|37650997|emb|CAD54073.1| sulphonylurea receptor 1 [Rattus nor...   399   e-109
gi|30682473|ref|NP_850575.1| ABC transporter family protein [Ara...   399   e-109
gi|19862855|sp|Q09429|ACC8_RAT Sulfonylurea receptor 1 >gnl|BL_O...   399   e-109
gi|11691886|dbj|BAB19011.1| sulphonylurea receptor 1 [Rattus nor...   399   e-109
gi|15778680|gb|AAL07506.1| sulphonylurea receptor 2B [Oryctolagu...   398   e-109
gi|34784298|gb|AAH57080.1| Abcc8 protein [Mus musculus]               398   e-109
gi|26350847|dbj|BAC39060.1| unnamed protein product [Mus musculus]    398   e-109
gi|50419409|ref|XP_458231.1| unnamed protein product [Debaryomyc...   397   e-108
gi|47220281|emb|CAG03315.1| unnamed protein product [Tetraodon n...   397   e-108
gi|50729100|ref|XP_416430.1| PREDICTED: similar to Sulfonylurea ...   397   e-108
gi|25513787|pir||H89715 protein F14F4.3 [imported] - Caenorhabdi...   397   e-108
gi|17551702|ref|NP_510478.1| multidrug Resistance Protein (mrp-5...   397   e-108
gi|3643190|gb|AAC36724.1| sulfonylurea receptor 1 [Homo sapiens]      396   e-108
gi|6920064|sp|Q09428|ACC8_HUMAN Sulfonylurea receptor 1               396   e-108
gi|1083191|pir||A56248 sulfonylurea receptor - golden hamster         396   e-108
gi|6981606|ref|NP_037171.1| ATP-binding cassette, subfamily C (C...   395   e-108
gi|6322980|ref|NP_013052.1| Yeast bile transporter, similar to m...   395   e-108
gi|1369844|gb|AAB02278.1| sulfonylurea receptor >gnl|BL_ORD_ID|7...   395   e-108
gi|1374920|gb|AAB02418.1| alternative splice (exon 17)                395   e-108
gi|4507317|ref|NP_000343.1| ATP-binding cassette, sub-family C, ...   394   e-107
gi|18202413|sp|P82451|ACC9_RABIT Sulfonylurea receptor 2 >gnl|BL...   394   e-107
gi|46229609|gb|EAK90427.1| ABC ATpase (2 ABC domains) with 10 tr...   392   e-107
gi|50747828|ref|XP_421005.1| PREDICTED: similar to alternative s...   391   e-107
gi|50553050|ref|XP_503935.1| hypothetical protein [Yarrowia lipo...   391   e-107
gi|11038666|ref|NP_066379.1| ATP-binding cassette, sub-family C,...   389   e-106
gi|17551372|ref|NP_510616.1| multidrug Resistance Protein (mrp-3...   389   e-106
gi|50555816|ref|XP_505316.1| hypothetical protein [Yarrowia lipo...   389   e-106
gi|5032135|ref|NP_005682.1| ATP-binding cassette, sub-family C, ...   388   e-106
gi|10947124|ref|NP_064694.1| ATP-binding cassette, sub-family C,...   388   e-106
gi|9280227|dbj|BAB01717.1| multidrug resistance-associated prote...   388   e-106
gi|11277356|pir||T47796 ABC transporter-like protein - Arabidops...   386   e-105
gi|22331862|ref|NP_191473.2| ABC transporter family protein [Ara...   386   e-105
gi|47847372|dbj|BAD21358.1| mFLJ00002 protein [Mus musculus]          386   e-105
gi|50552606|ref|XP_503713.1| hypothetical protein [Yarrowia lipo...   385   e-105
gi|46107572|ref|XP_380845.1| hypothetical protein FG00669.1 [Gib...   385   e-105
gi|50307943|ref|XP_453970.1| unnamed protein product [Kluyveromy...   384   e-104
gi|50557404|ref|XP_506110.1| hypothetical protein [Yarrowia lipo...   382   e-104
gi|34898286|ref|NP_910489.1| canalicular multispecific organic a...   382   e-104
gi|38346703|emb|CAE04853.2| OSJNBa0086O06.1 [Oryza sativa (japon...   382   e-104
gi|32417852|ref|XP_329404.1| hypothetical protein [Neurospora cr...   382   e-104
gi|48138115|ref|XP_393388.1| similar to ENSANGP00000004277 [Apis...   380   e-103
gi|38105753|gb|EAA52141.1| hypothetical protein MG03736.4 [Magna...   380   e-103
gi|7404488|sp|P36028|YK83_YEAST Probable ATP-dependent permease ...   380   e-103
gi|50258231|gb|EAL20925.1| hypothetical protein CNBE2860 [Crypto...   379   e-103
gi|50286861|ref|XP_445860.1| unnamed protein product [Candida gl...   379   e-103
gi|2773162|gb|AAB96684.1| sulfonylurea receptor 1B [Rattus norve...   377   e-102
gi|49067550|ref|XP_398065.1| hypothetical protein UM00450.1 [Ust...   377   e-102
gi|2585773|gb|AAB83980.1| multidrug resistance protein [Homo sap...   374   e-101
gi|9955952|ref|NP_063953.1| ATP-binding cassette, sub-family C, ...   374   e-101
gi|38105780|gb|EAA52163.1| hypothetical protein MG04855.4 [Magna...   373   e-101
gi|6715561|ref|NP_001162.2| ATP-binding cassette, sub-family C, ...   371   e-101
gi|45185616|ref|NP_983332.1| ACL072Cp [Eremothecium gossypii] >g...   371   e-101
gi|50305753|ref|XP_452837.1| unnamed protein product [Kluyveromy...   371   e-101
gi|22022396|gb|AAL47686.1| multidrug resistance-associated prote...   370   e-100
gi|50260357|gb|EAL23016.1| hypothetical protein CNBA7830 [Crypto...   370   e-100
gi|19172038|gb|AAL85711.1| ABC transporter ABCC.8 [Dictyostelium...   368   e-100
gi|5764415|gb|AAD51293.1| multi-specific organic anion tranporte...   368   e-100
gi|30686160|ref|NP_188762.2| ABC transporter family protein [Ara...   367   1e-99
gi|16304672|emb|CAC83020.1| multidrug resistance protein A [Tryp...   367   1e-99
gi|32404560|ref|XP_322893.1| hypothetical protein [Neurospora cr...   367   1e-99
gi|22553016|emb|CAD44995.1| multidrug-resistance related protein...   367   2e-99
gi|50256995|gb|EAL19713.1| hypothetical protein CNBG3410 [Crypto...   366   2e-99
gi|50260326|gb|EAL22985.1| hypothetical protein CNBA7530 [Crypto...   365   4e-99
gi|19920928|ref|NP_609207.1| CG7806-PA [Drosophila melanogaster]...   364   9e-99
gi|49100997|ref|XP_410916.1| hypothetical protein AN6779.2 [Aspe...   362   4e-98
gi|2585776|gb|AAB83983.1| multidrug resistance protein [Homo sap...   358   6e-97
gi|9955956|ref|NP_063955.1| ATP-binding cassette, sub-family C, ...   358   6e-97
gi|9055156|ref|NP_061265.1| ATP-binding cassette, sub-family C, ...   358   8e-97
gi|9955954|ref|NP_063954.1| ATP-binding cassette, sub-family C, ...   355   4e-96
gi|2585775|gb|AAB83982.1| multidrug resistance protein [Homo sap...   355   4e-96
gi|50258918|gb|EAL21599.1| hypothetical protein CNBC6360 [Crypto...   355   5e-96
gi|29612524|gb|AAH49980.1| Abcc6 protein [Mus musculus]               355   5e-96
gi|46139027|ref|XP_391204.1| hypothetical protein FG11028.1 [Gib...   353   2e-95
gi|6635093|emb|CAB64568.1| multidrug resistance protein, copy 1 ...   353   3e-95
gi|7520768|pir||T18343 P-glycoprotein - Sauroleishmania tarentol...   352   6e-95
gi|42524005|ref|NP_969385.1| ABC-type multidrug transporter with...   349   4e-94
gi|27371328|gb|AAH41560.1| ABCC4 protein [Homo sapiens]               348   6e-94
gi|27368891|emb|CAD59603.1| MRP-like ABC transporter [Oryza sati...   348   8e-94
gi|6635094|emb|CAB64569.1| multidrug resistance protein, copy 2 ...   347   1e-93
gi|13591916|ref|NP_112275.1| liver multidrug resistance-associat...   347   1e-93
gi|19697910|gb|AAL89812.1| ABC transporter ABCC.14 [Dictyosteliu...   346   3e-93
gi|17066744|gb|AAL35383.1| putative ABC transporter [Chlamydomon...   344   1e-92
gi|19115470|ref|NP_594558.1| putative ABC transporter [Schizosac...   344   1e-92
gi|29248499|gb|EAA40031.1| GLP_387_10931_6135 [Giardia lamblia A...   342   4e-92
gi|47208268|emb|CAF91950.1| unnamed protein product [Tetraodon n...   341   8e-92
gi|10440406|dbj|BAB15736.1| FLJ00036 protein [Homo sapiens]           340   1e-91
gi|11360097|pir||T43469 hypothetical protein DKFZp434L0827.1 - h...   340   2e-91
gi|19115497|ref|NP_594585.1| atp-binding cassette transporter ab...   338   7e-91
gi|31225415|ref|XP_317569.1| ENSANGP00000007239 [Anopheles gambi...   338   9e-91
gi|38110281|gb|EAA56023.1| hypothetical protein MG01674.4 [Magna...   332   5e-89
gi|19699106|gb|AAL90919.1| At1g30400/T4K22_12 [Arabidopsis thali...   332   6e-89
gi|7520769|pir||T30821 P-glycoprotein - Sauroleishmania tarentol...   331   1e-88
gi|50730645|ref|XP_416986.1| PREDICTED: similar to ATP-binding c...   330   2e-88
gi|29250022|gb|EAA41523.1| GLP_623_62539_67263 [Giardia lamblia ...   329   3e-88
gi|46117196|ref|XP_384616.1| hypothetical protein FG04440.1 [Gib...   325   4e-87
gi|46850470|gb|AAT02643.1| P-glycoprotein D [Leishmania tarentolae]   321   8e-86
gi|19172048|gb|AAL85716.1| ABC transporter ABCC.13 [Dictyosteliu...   321   8e-86
gi|50740599|ref|XP_419506.1| PREDICTED: similar to FLJ00002 prot...   320   2e-85
gi|49132374|ref|XP_413094.1| hypothetical protein AN8957.2 [Aspe...   318   5e-85
gi|50256716|gb|EAL19437.1| hypothetical protein CNBH0090 [Crypto...   314   1e-83
gi|49076682|ref|XP_402289.1| hypothetical protein UM04674.1 [Ust...   310   1e-82
gi|3851490|gb|AAC72293.1| sulfonylurea receptor-1 [Mus musculus]      310   3e-82
gi|47211711|emb|CAF95866.1| unnamed protein product [Tetraodon n...   308   6e-82
gi|49072751|ref|XP_400663.1| hypothetical protein UM03048.1 [Ust...   306   3e-81
gi|7494074|pir||T18344 P-glycoprotein E - Leishmania tropica >gn...   306   4e-81
gi|2439970|gb|AAB71756.1| multidrug resistance-associated protei...   305   5e-81
gi|46110869|ref|XP_382492.1| hypothetical protein FG02316.1 [Gib...   305   6e-81
gi|38109025|gb|EAA54955.1| hypothetical protein MG05746.4 [Magna...   305   8e-81
gi|29247443|gb|EAA39005.1| GLP_542_19609_24120 [Giardia lamblia ...   302   4e-80
gi|46136191|ref|XP_389787.1| hypothetical protein FG09611.1 [Gib...   302   4e-80
gi|12007307|gb|AAG45125.1| unknown [Dictyostelium discoideum]         300   2e-79
gi|18845015|gb|AAL79528.1| ATP-binding cassette protein C12 isof...   298   6e-79
gi|49111442|ref|XP_411813.1| hypothetical protein AN7676.2 [Aspe...   298   1e-78
gi|32264580|gb|AAP78734.1| ABC transporter [Alternaria brassicae]     296   2e-78
gi|49114214|ref|XP_412016.1| hypothetical protein AN7879.2 [Aspe...   296   2e-78
gi|32411513|ref|XP_326237.1| hypothetical protein [Neurospora cr...   296   3e-78
gi|13925693|gb|AAK49412.1| multidrug resistance protein MDR [Coc...   295   8e-78
gi|46136383|ref|XP_389883.1| hypothetical protein FG09707.1 [Gib...   294   1e-77
gi|38605757|emb|CAE04329.3| OSJNBb0016D16.20 [Oryza sativa (japo...   291   9e-77
gi|49070168|ref|XP_399373.1| hypothetical protein UM01758.1 [Ust...   291   1e-76
gi|48095348|ref|XP_394420.1| similar to ENSANGP00000015733 [Apis...   289   4e-76
gi|26342527|dbj|BAC34920.1| unnamed protein product [Mus musculus]    288   8e-76
gi|116141|sp|P26362|CFTR_SQUAC Cystic fibrosis transmembrane con...   286   2e-75
gi|47212333|emb|CAF95602.1| unnamed protein product [Tetraodon n...   285   7e-75
gi|1871200|gb|AAC15784.1| Multiple drug resistance gene MRP1 (5'...   284   1e-74
gi|46435946|gb|EAK95318.1| hypothetical protein CaO19.9350 [Cand...   284   1e-74
gi|46110515|ref|XP_382315.1| hypothetical protein FG02139.1 [Gib...   283   2e-74
gi|49070142|ref|XP_399360.1| hypothetical protein UM01745.1 [Ust...   282   4e-74
gi|49074722|ref|XP_401476.1| hypothetical protein UM03861.1 [Ust...   278   6e-73
gi|7442654|pir||JC6139 cystic fibrosis transmembrane conductance...   278   1e-72
gi|6995996|ref|NP_000483.2| cystic fibrosis transmembrane conduc...   277   2e-72
gi|34859564|ref|XP_347230.1| similar to cystic fibrosis transmem...   276   2e-72
gi|34854998|ref|XP_342646.1| cystic fibrosis transmembrane condu...   276   2e-72
gi|1705762|sp|P13569|CFTR_HUMAN Cystic fibrosis transmembrane co...   276   3e-72
gi|1705763|sp|Q00554|CFTR_RABIT Cystic fibrosis transmembrane co...   275   7e-72
gi|382755|prf||1901178A cystic fibrosis transmembrane conductanc...   274   1e-71
gi|3047171|gb|AAC14011.1| cystic fibrosis transmembrane conducta...   274   1e-71
gi|46138961|ref|XP_391171.1| hypothetical protein FG10995.1 [Gib...   274   2e-71
gi|5679250|gb|AAD46905.1| cystic fibrosis transmembrane conducta...   274   2e-71
gi|6007843|gb|AAF01067.1| chloride channel [Oryctolagus cuniculus]    274   2e-71
gi|3057116|gb|AAC14012.1| cystic fibrosis transmembrane conducta...   273   2e-71
gi|5679281|gb|AAD46907.1| cystic fibrosis transmembrane conducta...   273   2e-71
gi|47933788|gb|AAT39475.1| cystic fibrosis transmembrane conduct...   273   3e-71
gi|4886898|gb|AAD32093.1| ATP-binding cassette protein [Cryptosp...   270   2e-70
gi|50728160|ref|XP_416011.1| PREDICTED: similar to chloride chan...   269   5e-70
gi|49086698|ref|XP_405377.1| hypothetical protein AN1240.2 [Aspe...   269   5e-70
gi|1749670|dbj|BAA13892.1| similar to Saccharomyces cerevisiae m...   268   6e-70
gi|31221070|ref|XP_317002.1| ENSANGP00000006599 [Anopheles gambi...   268   8e-70
gi|2506121|sp|Q00555|CFTR_SHEEP Cystic fibrosis transmembrane co...   268   1e-69
gi|27806695|ref|NP_776443.1| cystic fibrosis transmembrane condu...   268   1e-69
gi|46452255|gb|AAS98211.1| cystic fibrosis transmembrane conduct...   268   1e-69
gi|12963887|gb|AAK07685.1| cystic fibrosis transmembrane conduct...   268   1e-69
gi|116142|sp|P26363|CFTR_XENLA Cystic fibrosis transmembrane con...   265   5e-69
gi|14141185|ref|NP_066388.1| cystic fibrosis transmembrane condu...   265   7e-69
gi|6862589|gb|AAF30300.1| cystic fibrosis transmembrane conducta...   265   7e-69
gi|109761|pir||A39901 cystic fibrosis transmembrane conductance ...   265   7e-69
gi|3015540|gb|AAC41271.1| cystic fibrosis transmembrane conducta...   263   3e-68
gi|37194864|gb|AAH58185.1| Abcc3 protein [Mus musculus]               263   4e-68
gi|1617482|gb|AAC60023.1| cystic fibrosis transmembrane conducta...   261   1e-67
gi|8777715|gb|AAF79060.1| sulphonylurea receptor 2A [Cavia porce...   259   5e-67
gi|49083798|ref|XP_404152.1| hypothetical protein AN0015.2 [Aspe...   258   9e-67
gi|31212475|ref|XP_315222.1| ENSANGP00000021575 [Anopheles gambi...   257   2e-66
gi|50545421|ref|XP_500248.1| hypothetical protein [Yarrowia lipo...   257   2e-66
gi|5052017|gb|AAD38404.1| cystic fibrosis transmembrane conducta...   256   3e-66
gi|12746235|gb|AAK07405.1| cystic fibrosis transmembrane conduct...   256   3e-66
gi|38105953|gb|EAA52317.1| hypothetical protein MG05009.4 [Magna...   255   7e-66
gi|7188560|gb|AAF37801.1| cystic fibrosis transmembrane conducta...   254   1e-65
gi|8980337|emb|CAB96905.1| cystic fibrosis transmembrane conduct...   254   2e-65
gi|47847937|dbj|BAD21727.1| putative MRP-like ABC transporter [O...   253   3e-65
gi|27368885|emb|CAD59600.1| MRP-like ABC transporter [Oryza sati...   253   3e-65
gi|50781241|ref|XP_423362.1| PREDICTED: similar to Multidrug res...   251   1e-64
gi|32566680|ref|NP_507812.2| multidrug Resistance Protein (125.4...   249   4e-64
gi|7509819|pir||T26883 hypothetical protein Y43F8C.12 - Caenorha...   249   4e-64
gi|47209056|emb|CAF93260.1| unnamed protein product [Tetraodon n...   249   4e-64
gi|47216707|emb|CAG00981.1| unnamed protein product [Tetraodon n...   249   4e-64
gi|21729886|ref|NP_660188.1| ATP-binding cassette, sub-family C,...   247   2e-63
gi|12804459|gb|AAH01636.1| Unknown (protein for IMAGE:3355848) [...   246   3e-63
gi|784882|gb|AAA99227.1| sulfonylurea receptor                        246   3e-63
gi|18848267|gb|AAH24103.1| ABCC10 protein [Homo sapiens]              245   8e-63
gi|25395351|pir||C87973 protein Y43F8C.12 [imported] - Caenorhab...   244   2e-62
gi|50258065|gb|EAL20759.1| hypothetical protein CNBE1220 [Crypto...   242   5e-62
gi|27374345|gb|AAO01086.1| CG4562-PA [Drosophila willistoni]          241   1e-61
gi|5031476|gb|AAD38185.1| MRP3s1 protein [Homo sapiens]               239   3e-61
gi|50729846|ref|XP_416677.1| PREDICTED: similar to ATP-binding c...   239   4e-61
gi|32453000|gb|AAP82650.1| Multidrug resistance protein family p...   237   2e-60
gi|49079552|ref|XP_403409.1| hypothetical protein UM05794.1 [Ust...   237   2e-60
gi|32404928|ref|XP_323077.1| hypothetical protein ( (AL513466) r...   236   5e-60
gi|47224506|emb|CAG08756.1| unnamed protein product [Tetraodon n...   235   8e-60
gi|8777713|gb|AAF79059.1| sulphonylurea receptor 1C [Cavia porce...   232   7e-59
gi|6322957|ref|NP_013030.1| ORFs YKR103W and YKR104W are merged ...   232   7e-59
gi|18845017|gb|AAL79529.1| ATP-binding cassette protein C12 isof...   228   7e-58
gi|32420053|ref|XP_330470.1| hypothetical protein [Neurospora cr...   228   1e-57
gi|25294143|gb|AAN74822.1| Fum19p [Gibberella moniliformis]           228   1e-57
gi|39593147|emb|CAE64616.1| Hypothetical protein CBG09374 [Caeno...   226   3e-57
gi|8777717|gb|AAF79061.1| sulphonylurea receptor 2B [Cavia porce...   222   7e-56
gi|1279457|emb|CAA65019.1| anthracycline resistance associated p...   221   1e-55
gi|31233537|ref|XP_318893.1| ENSANGP00000015146 [Anopheles gambi...   220   2e-55
gi|37674391|gb|AAB46340.2| unknown [Homo sapiens]                     220   3e-55
gi|2316024|gb|AAC49798.1| MRP-like ABC transporter [Arabidopsis ...   220   3e-55
gi|2316022|gb|AAC49797.1| MRP-like ABC transporter [Arabidopsis ...   218   8e-55
gi|17558094|ref|NP_504463.1| mrp-like ABC transporter (5G25) [Ca...   217   2e-54
gi|50755783|ref|XP_414900.1| PREDICTED: similar to Multidrug res...   216   3e-54
gi|47214074|emb|CAF95331.1| unnamed protein product [Tetraodon n...   214   2e-53
gi|7512614|pir||T34527 hypothetical protein DKFZp434I2115.1 - hu...   213   3e-53
gi|18152937|gb|AAC47653.2| ATP-binding cassette protein 1 [Crypt...   210   2e-52
gi|47220876|emb|CAG03083.1| unnamed protein product [Tetraodon n...   209   5e-52
gi|34915038|ref|NP_918866.1| putative multi resistance protein A...   209   6e-52
gi|31221096|ref|XP_317006.1| ENSANGP00000019169 [Anopheles gambi...   206   4e-51
gi|48100859|ref|XP_395036.1| similar to CG5789-PA [Apis mellifera]    205   9e-51
gi|46123527|ref|XP_386317.1| hypothetical protein FG06141.1 [Gib...   204   2e-50
gi|42523968|ref|NP_969348.1| ABC-type multidrug transporter with...   204   2e-50
gi|16944697|emb|CAC28822.2| related to multidrug resistance-asso...   203   3e-50
gi|46127861|ref|XP_388484.1| hypothetical protein FG08308.1 [Gib...   196   3e-48
gi|49119361|ref|XP_412287.1| hypothetical protein AN8150.2 [Aspe...   196   5e-48
gi|42572407|ref|NP_974299.1| ABC transporter family protein [Ara...   190   3e-46
gi|9955972|ref|NP_064421.1| ATP-binding cassette, sub-family C, ...   186   5e-45
gi|30019026|ref|NP_830657.1| Multidrug resistance ABC transporte...   185   7e-45
gi|39594943|emb|CAE70811.1| Hypothetical protein CBG17574 [Caeno...   185   9e-45
gi|49113744|ref|XP_411976.1| hypothetical protein AN7839.2 [Aspe...   184   2e-44
gi|47564800|ref|ZP_00235844.1| ABC transporter, ATP-binding/perm...   184   2e-44
gi|42526433|ref|NP_971531.1| ABC transporter, ATP-binding/permea...   184   2e-44
gi|49476945|ref|YP_035103.1| multidrug resistance ABC transporte...   184   2e-44
gi|24372343|ref|NP_716385.1| ABC transporter, ATP-binding protei...   183   3e-44
gi|42780019|ref|NP_977266.1| ABC transporter, ATP-binding/permea...   183   3e-44
gi|15614898|ref|NP_243201.1| ABC transporter (ATP-binding protei...   182   6e-44
gi|15613689|ref|NP_241992.1| ABC transporter (ATP-binding protei...   181   1e-43
gi|16304674|emb|CAC83023.1| multidrug resistance protein E [Tryp...   181   1e-43
gi|47216706|emb|CAG00980.1| unnamed protein product [Tetraodon n...   180   1e-43
gi|17137736|ref|NP_477472.1| CG5772-PA [Drosophila melanogaster]...   181   2e-43
gi|17863018|gb|AAL39986.1| SD08664p [Drosophila melanogaster]         181   2e-43
gi|6288773|gb|AAF06736.1| sulfonyl urea receptor [Drosophila mel...   181   2e-43
gi|23098687|ref|NP_692153.1| ABC transporter ATP-binding protein...   180   2e-43
gi|46113651|ref|ZP_00183228.2| COG1132: ABC-type multidrug trans...   179   5e-43
gi|50590389|ref|ZP_00331775.1| COG1132: ABC-type multidrug trans...   179   7e-43
gi|46912593|emb|CAG19383.1| Putative ATP-binding component of a ...   178   9e-43
gi|24379007|ref|NP_720962.1| putative ABC transporter, ATP-bindi...   178   9e-43
gi|30021775|ref|NP_833406.1| Multidrug resistance ABC transporte...   177   3e-42
gi|21729888|ref|NP_660189.1| ATP-binding cassette, sub-family C,...   177   3e-42
gi|49478324|ref|YP_037753.1| ABC transporter, ATP-binding protei...   176   3e-42
gi|21401596|ref|NP_657581.1| ABC_tran, ABC transporter [Bacillus...   176   3e-42
gi|25011449|ref|NP_735844.1| unknown [Streptococcus agalactiae N...   176   4e-42
gi|15673254|ref|NP_267428.1| ABC transporter ABC binding and per...   176   6e-42
gi|33352112|emb|CAD43191.1| multidrug resistance-associated prot...   176   6e-42
gi|16329858|ref|NP_440586.1| ABC transporter [Synechocystis sp. ...   176   6e-42
gi|15899719|ref|NP_344324.1| ABC transporter, ATP binding protei...   176   6e-42


>gi|17567189|ref|NP_508710.1| multidrug Resistance Protein (mrp-6)
            [Caenorhabditis elegans]
 gi|7499473|pir||T34225 hypothetical protein F20B6.3 - Caenorhabditis
            elegans
          Length = 1421

 Score = 2614 bits (6775), Expect = 0.0
 Identities = 1334/1421 (93%), Positives = 1334/1421 (93%)
 Frame = -1

Query: 4266 MIPHFQKTPDETKPDVNLESVEGYHPSSEDSAGLISSILFSFVGFYWWRTRNAQTDTDLL 4087
            MIPHFQKTPDETKPDVNLESVEGYHPSSEDSAGLISSILFSFVGFYWWRTRNAQTDTDLL
Sbjct: 1    MIPHFQKTPDETKPDVNLESVEGYHPSSEDSAGLISSILFSFVGFYWWRTRNAQTDTDLL 60

Query: 4086 EKPSKGISAKYAAQKLESKWISSGPKRTHFLVGVWHCTKVSVMAHAISLCLEELTRVAQP 3907
            EKPSKGISAKYAAQKLESKWISSGPKRTHFLVGVWHCTKVSVMAHAISLCLEELTRVAQP
Sbjct: 61   EKPSKGISAKYAAQKLESKWISSGPKRTHFLVGVWHCTKVSVMAHAISLCLEELTRVAQP 120

Query: 3906 LLLRELMSYYDIEEGQEFPYWPAMQVALIISLLSFVTVCIHHPYFHGLLKVGNHARVATG 3727
            LLLRELMSYYDIEEGQEFPYWPAMQVALIISLLSFVTVCIHHPYFHGLLKVGNHARVATG
Sbjct: 121  LLLRELMSYYDIEEGQEFPYWPAMQVALIISLLSFVTVCIHHPYFHGLLKVGNHARVATG 180

Query: 3726 VLLYRKSLRISLTSLFETNSGQIIQLLNTDAAKLEQAFLFAHYVWLCPLLMFFYAYILWS 3547
            VLLYRKSLRISLTSLFETNSGQIIQLLNTDAAKLEQAFLFAHYVWLCPLLMFFYAYILWS
Sbjct: 181  VLLYRKSLRISLTSLFETNSGQIIQLLNTDAAKLEQAFLFAHYVWLCPLLMFFYAYILWS 240

Query: 3546 MFGFCCLLGFLVMMAIVSFQVHYSYQLGVNRRNIGDKMDSRLKVMSEIINGIKVIKMHGW 3367
            MFGFCCLLGFLVMMAIVSFQVHYSYQLGVNRRNIGDKMDSRLKVMSEIINGIKVIKMHGW
Sbjct: 241  MFGFCCLLGFLVMMAIVSFQVHYSYQLGVNRRNIGDKMDSRLKVMSEIINGIKVIKMHGW 300

Query: 3366 ENAFAEKIRILREDEIKAVGTSAFYSSMVMGIYFISAKIGLFVYIFACDYFDEILTTRGV 3187
            ENAFAEKIRILREDEIKAVGTSAFYSSMVMGIYFISAKIGLFVYIFACDYFDEILTTRGV
Sbjct: 301  ENAFAEKIRILREDEIKAVGTSAFYSSMVMGIYFISAKIGLFVYIFACDYFDEILTTRGV 360

Query: 3186 FASSALFNSVXXXXXXXXXXXXXXXXXXFSTSRRIDLFFCLEEYSRITLELDSTDTEDGS 3007
            FASSALFNSV                  FSTSRRIDLFFCLEEYSRITLELDSTDTEDGS
Sbjct: 361  FASSALFNSVRLPFALFLPLGLLFGRELFSTSRRIDLFFCLEEYSRITLELDSTDTEDGS 420

Query: 3006 KNEKEGLTLKKIGEKPSWTLKCDKAEKTSVFLNKVTAVWYXXXXXXXXXXXXXXXXXXDN 2827
            KNEKEGLTLKKIGEKPSWTLKCDKAEKTSVFLNKVTAVWY                  DN
Sbjct: 421  KNEKEGLTLKKIGEKPSWTLKCDKAEKTSVFLNKVTAVWYDKDEHDQKKKKKNFKALSDN 480

Query: 2826 DATVIAGEKKDEPLHVVYAVQDLSFEFVAGTCYXXXXXXXXXXXXXXLTILSESRMTRGN 2647
            DATVIAGEKKDEPLHVVYAVQDLSFEFVAGTCY              LTILSESRMTRGN
Sbjct: 481  DATVIAGEKKDEPLHVVYAVQDLSFEFVAGTCYGIIGSVGSGKSSLLLTILSESRMTRGN 540

Query: 2646 LSVNGSFAYCAQEPWIFTGSIQDNIVFGSEFNKERYENALELCLLTPDLRQFANGDMTIV 2467
            LSVNGSFAYCAQEPWIFTGSIQDNIVFGSEFNKERYENALELCLLTPDLRQFANGDMTIV
Sbjct: 541  LSVNGSFAYCAQEPWIFTGSIQDNIVFGSEFNKERYENALELCLLTPDLRQFANGDMTIV 600

Query: 2466 GDNGSTLSGGQXXXXXXXXXXXXXXDIYLLDDPLSAVDAHVGKKLYENLIRGFLSDKLVI 2287
            GDNGSTLSGGQ              DIYLLDDPLSAVDAHVGKKLYENLIRGFLSDKLVI
Sbjct: 601  GDNGSTLSGGQRARVALARAVYADADIYLLDDPLSAVDAHVGKKLYENLIRGFLSDKLVI 660

Query: 2286 LVTHQIHFLSELDSVILMKNNKMVGNGSLDELKSTFTDDFIKLQAVETEVQSDELFVDGX 2107
            LVTHQIHFLSELDSVILMKNNKMVGNGSLDELKSTFTDDFIKLQAVETEVQSDELFVDG
Sbjct: 661  LVTHQIHFLSELDSVILMKNNKMVGNGSLDELKSTFTDDFIKLQAVETEVQSDELFVDGP 720

Query: 2106 XXXXXXXPVNIESMEKINKESIFQRANSVLSGSKMSETEYVKEIVYESRKSGTISWSVYW 1927
                   PVNIESMEKINKESIFQRANSVLSGSKMSETEYVKEIVYESRKSGTISWSVYW
Sbjct: 721  PSSPPPSPVNIESMEKINKESIFQRANSVLSGSKMSETEYVKEIVYESRKSGTISWSVYW 780

Query: 1926 EYTRGVINPLKYGIWLVVCVLITQLMNNFVDWWLNKWLVDLDMNNADNSTSKEEFNRNVD 1747
            EYTRGVINPLKYGIWLVVCVLITQLMNNFVDWWLNKWLVDLDMNNADNSTSKEEFNRNVD
Sbjct: 781  EYTRGVINPLKYGIWLVVCVLITQLMNNFVDWWLNKWLVDLDMNNADNSTSKEEFNRNVD 840

Query: 1746 VLGYTFNVTFQTYELTFIISTVIMSILGVVRSVWFRNAQLMASRILHNSMFDCVLKTESE 1567
            VLGYTFNVTFQTYELTFIISTVIMSILGVVRSVWFRNAQLMASRILHNSMFDCVLKTESE
Sbjct: 841  VLGYTFNVTFQTYELTFIISTVIMSILGVVRSVWFRNAQLMASRILHNSMFDCVLKTESE 900

Query: 1566 FFDKNSEGMILNRFSKDIGLTDDLLAFTYFEFVFGTLTFVGIVGLVSMVRPIVILACAFI 1387
            FFDKNSEGMILNRFSKDIGLTDDLLAFTYFEFVFGTLTFVGIVGLVSMVRPIVILACAFI
Sbjct: 901  FFDKNSEGMILNRFSKDIGLTDDLLAFTYFEFVFGTLTFVGIVGLVSMVRPIVILACAFI 960

Query: 1386 TAGFYFCRKMYVHRSRELKRIEAAARSPLNTTITSTVHGLSTIRAYRKENEMIEKFCALH 1207
            TAGFYFCRKMYVHRSRELKRIEAAARSPLNTTITSTVHGLSTIRAYRKENEMIEKFCALH
Sbjct: 961  TAGFYFCRKMYVHRSRELKRIEAAARSPLNTTITSTVHGLSTIRAYRKENEMIEKFCALH 1020

Query: 1206 DVYMAAYNMGLLSARWFGICIDXXXXXXXXXXXXXXXLQYETLTVGEVGLCLVCAVQLSG 1027
            DVYMAAYNMGLLSARWFGICID               LQYETLTVGEVGLCLVCAVQLSG
Sbjct: 1021 DVYMAAYNMGLLSARWFGICIDFLVSVFVSIVAIVVVLQYETLTVGEVGLCLVCAVQLSG 1080

Query: 1026 FFSWIMRQSAELENGMVSVERVLEYTKLKSEEEARRPHDAYLDKQLLNSWPTKGEIEFEN 847
            FFSWIMRQSAELENGMVSVERVLEYTKLKSEEEARRPHDAYLDKQLLNSWPTKGEIEFEN
Sbjct: 1081 FFSWIMRQSAELENGMVSVERVLEYTKLKSEEEARRPHDAYLDKQLLNSWPTKGEIEFEN 1140

Query: 846  VSVNYGETKVLKNLSFVVLGGQKIGVVGRTGAGKSTLIKIIFGLKEYCSGRVTIDGVDLD 667
            VSVNYGETKVLKNLSFVVLGGQKIGVVGRTGAGKSTLIKIIFGLKEYCSGRVTIDGVDLD
Sbjct: 1141 VSVNYGETKVLKNLSFVVLGGQKIGVVGRTGAGKSTLIKIIFGLKEYCSGRVTIDGVDLD 1200

Query: 666  HISLNFRRGGMSIIPQEPVIFSGTVRENLDPFDEYDDATIWFALEQCELKRSITKEKGLN 487
            HISLNFRRGGMSIIPQEPVIFSGTVRENLDPFDEYDDATIWFALEQCELKRSITKEKGLN
Sbjct: 1201 HISLNFRRGGMSIIPQEPVIFSGTVRENLDPFDEYDDATIWFALEQCELKRSITKEKGLN 1260

Query: 486  VELGQRGVSLSVGQRQLFCLARAMIHRSKILVIDEATANVDGVTDACIQKTIRDFFKNAT 307
            VELGQRGVSLSVGQRQLFCLARAMIHRSKILVIDEATANVDGVTDACIQKTIRDFFKNAT
Sbjct: 1261 VELGQRGVSLSVGQRQLFCLARAMIHRSKILVIDEATANVDGVTDACIQKTIRDFFKNAT 1320

Query: 306  IITVAHRLHTIMNSDNVMVFEKGELVEFDKPITLLDDQSSLFSRMAAQSGAENFDSLRAA 127
            IITVAHRLHTIMNSDNVMVFEKGELVEFDKPITLLDDQSSLFSRMAAQSGAENFDSLRAA
Sbjct: 1321 IITVAHRLHTIMNSDNVMVFEKGELVEFDKPITLLDDQSSLFSRMAAQSGAENFDSLRAA 1380

Query: 126  ALAHAIDDQSSYTDNTIQLFNVTFSKGIEIVFISLFIPSFH 4
            ALAHAIDDQSSYTDNTIQLFNVTFSKGIEIVFISLFIPSFH
Sbjct: 1381 ALAHAIDDQSSYTDNTIQLFNVTFSKGIEIVFISLFIPSFH 1421


>gi|30794620|gb|AAA82317.2| Multidrug resistance protein family
            protein 6 [Caenorhabditis elegans]
          Length = 1396

 Score = 2564 bits (6646), Expect = 0.0
 Identities = 1308/1396 (93%), Positives = 1309/1396 (93%)
 Frame = -1

Query: 4266 MIPHFQKTPDETKPDVNLESVEGYHPSSEDSAGLISSILFSFVGFYWWRTRNAQTDTDLL 4087
            MIPHFQKTPDETKPDVNLESVEGYHPSSEDSAGLISSILFSFVGFYWWRTRNAQTDTDLL
Sbjct: 1    MIPHFQKTPDETKPDVNLESVEGYHPSSEDSAGLISSILFSFVGFYWWRTRNAQTDTDLL 60

Query: 4086 EKPSKGISAKYAAQKLESKWISSGPKRTHFLVGVWHCTKVSVMAHAISLCLEELTRVAQP 3907
            EKPSKGISAKYAAQKLESKWISSGPKRTHFLVGVWHCTKVSVMAHAISLCLEELTRVAQP
Sbjct: 61   EKPSKGISAKYAAQKLESKWISSGPKRTHFLVGVWHCTKVSVMAHAISLCLEELTRVAQP 120

Query: 3906 LLLRELMSYYDIEEGQEFPYWPAMQVALIISLLSFVTVCIHHPYFHGLLKVGNHARVATG 3727
            LLLRELMSYYDIEEGQEFPYWPAMQVALIISLLSFVTVCIHHPYFHGLLKVGNHARVATG
Sbjct: 121  LLLRELMSYYDIEEGQEFPYWPAMQVALIISLLSFVTVCIHHPYFHGLLKVGNHARVATG 180

Query: 3726 VLLYRKSLRISLTSLFETNSGQIIQLLNTDAAKLEQAFLFAHYVWLCPLLMFFYAYILWS 3547
            VLLYRKSLRISLTSLFETNSGQIIQLLNTDAAKLEQAFLFAHYVWLCPLLMFFYAYILWS
Sbjct: 181  VLLYRKSLRISLTSLFETNSGQIIQLLNTDAAKLEQAFLFAHYVWLCPLLMFFYAYILWS 240

Query: 3546 MFGFCCLLGFLVMMAIVSFQVHYSYQLGVNRRNIGDKMDSRLKVMSEIINGIKVIKMHGW 3367
            MFGFCCLLGFLVMMAIVSFQVHYSYQLGVNRRNIGDKMDSRLKVMSEIINGIKVIKMHGW
Sbjct: 241  MFGFCCLLGFLVMMAIVSFQVHYSYQLGVNRRNIGDKMDSRLKVMSEIINGIKVIKMHGW 300

Query: 3366 ENAFAEKIRILREDEIKAVGTSAFYSSMVMGIYFISAKIGLFVYIFACDYFDEILTTRGV 3187
            ENAFAEKIRILREDEIKAVGTSAFYSSMVMGIYFISAKIGLFVYIFACDYFDEILTTRGV
Sbjct: 301  ENAFAEKIRILREDEIKAVGTSAFYSSMVMGIYFISAKIGLFVYIFACDYFDEILTTRGV 360

Query: 3186 FASSALFNSVXXXXXXXXXXXXXXXXXXFSTSRRIDLFFCLEEYSRITLELDSTDTEDGS 3007
            FASSALFNSV                  FSTSRRIDLFFCLEEYSRITLELDSTDTEDGS
Sbjct: 361  FASSALFNSVRLPFALFLPLGLLFGRELFSTSRRIDLFFCLEEYSRITLELDSTDTEDGS 420

Query: 3006 KNEKEGLTLKKIGEKPSWTLKCDKAEKTSVFLNKVTAVWYXXXXXXXXXXXXXXXXXXDN 2827
            KNEKEGLTLKKIGEKPSWTLKCDKAEKTSVFLNKVTAVWY                  DN
Sbjct: 421  KNEKEGLTLKKIGEKPSWTLKCDKAEKTSVFLNKVTAVWYDKDEHDQKKKKKNFKALSDN 480

Query: 2826 DATVIAGEKKDEPLHVVYAVQDLSFEFVAGTCYXXXXXXXXXXXXXXLTILSESRMTRGN 2647
            DATVIAGEKKDEPLHVVYAVQDLSFEFVAGTCY              LTILSESRMTRGN
Sbjct: 481  DATVIAGEKKDEPLHVVYAVQDLSFEFVAGTCYGIIGSVGSGKSSLLLTILSESRMTRGN 540

Query: 2646 LSVNGSFAYCAQEPWIFTGSIQDNIVFGSEFNKERYENALELCLLTPDLRQFANGDMTIV 2467
            LSVNGSFAYCAQEPWIFTGSIQDNIVFGSEFNKERYENALELCLLTPDLRQFANGDMTIV
Sbjct: 541  LSVNGSFAYCAQEPWIFTGSIQDNIVFGSEFNKERYENALELCLLTPDLRQFANGDMTIV 600

Query: 2466 GDNGSTLSGGQXXXXXXXXXXXXXXDIYLLDDPLSAVDAHVGKKLYENLIRGFLSDKLVI 2287
            GDNGSTLSGGQ              DIYLLDDPLSAVDAHVGKKLYENLIRGFLSDKLVI
Sbjct: 601  GDNGSTLSGGQRARVALARAVYADADIYLLDDPLSAVDAHVGKKLYENLIRGFLSDKLVI 660

Query: 2286 LVTHQIHFLSELDSVILMKNNKMVGNGSLDELKSTFTDDFIKLQAVETEVQSDELFVDGX 2107
            LVTHQIHFLSELDSVILMKNNKMVGNGSLDELKSTFTDDFIKLQAVETEVQSDELFVDG
Sbjct: 661  LVTHQIHFLSELDSVILMKNNKMVGNGSLDELKSTFTDDFIKLQAVETEVQSDELFVDGP 720

Query: 2106 XXXXXXXPVNIESMEKINKESIFQRANSVLSGSKMSETEYVKEIVYESRKSGTISWSVYW 1927
                   PVNIESMEKINKESIFQRANSVLSGSKMSETEYVKEIVYESRKSGTISWSVYW
Sbjct: 721  PSSPPPSPVNIESMEKINKESIFQRANSVLSGSKMSETEYVKEIVYESRKSGTISWSVYW 780

Query: 1926 EYTRGVINPLKYGIWLVVCVLITQLMNNFVDWWLNKWLVDLDMNNADNSTSKEEFNRNVD 1747
            EYTRGVINPLKYGIWLVVCVLITQLMNNFVDWWLNKWLVDLDMNNADNSTSKEEFNRNVD
Sbjct: 781  EYTRGVINPLKYGIWLVVCVLITQLMNNFVDWWLNKWLVDLDMNNADNSTSKEEFNRNVD 840

Query: 1746 VLGYTFNVTFQTYELTFIISTVIMSILGVVRSVWFRNAQLMASRILHNSMFDCVLKTESE 1567
            VLGYTFNVTFQTYELTFIISTVIMSILGVVRSVWFRNAQLMASRILHNSMFDCVLKTESE
Sbjct: 841  VLGYTFNVTFQTYELTFIISTVIMSILGVVRSVWFRNAQLMASRILHNSMFDCVLKTESE 900

Query: 1566 FFDKNSEGMILNRFSKDIGLTDDLLAFTYFEFVFGTLTFVGIVGLVSMVRPIVILACAFI 1387
            FFDKNSEGMILNRFSKDIGLTDDLLAFTYFEFVFGTLTFVGIVGLVSMVRPIVILACAFI
Sbjct: 901  FFDKNSEGMILNRFSKDIGLTDDLLAFTYFEFVFGTLTFVGIVGLVSMVRPIVILACAFI 960

Query: 1386 TAGFYFCRKMYVHRSRELKRIEAAARSPLNTTITSTVHGLSTIRAYRKENEMIEKFCALH 1207
            TAGFYFCRKMYVHRSRELKRIEAAARSPLNTTITSTVHGLSTIRAYRKENEMIEKFCALH
Sbjct: 961  TAGFYFCRKMYVHRSRELKRIEAAARSPLNTTITSTVHGLSTIRAYRKENEMIEKFCALH 1020

Query: 1206 DVYMAAYNMGLLSARWFGICIDXXXXXXXXXXXXXXXLQYETLTVGEVGLCLVCAVQLSG 1027
            DVYMAAYNMGLLSARWFGICID               LQYETLTVGEVGLCLVCAVQLSG
Sbjct: 1021 DVYMAAYNMGLLSARWFGICIDFLVSVFVSIVAIVVVLQYETLTVGEVGLCLVCAVQLSG 1080

Query: 1026 FFSWIMRQSAELENGMVSVERVLEYTKLKSEEEARRPHDAYLDKQLLNSWPTKGEIEFEN 847
            FFSWIMRQSAELENGMVSVERVLEYTKLKSEEEARRPHDAYLDKQLLNSWPTKGEIEFEN
Sbjct: 1081 FFSWIMRQSAELENGMVSVERVLEYTKLKSEEEARRPHDAYLDKQLLNSWPTKGEIEFEN 1140

Query: 846  VSVNYGETKVLKNLSFVVLGGQKIGVVGRTGAGKSTLIKIIFGLKEYCSGRVTIDGVDLD 667
            VSVNYGETKVLKNLSFVVLGGQKIGVVGRTGAGKSTLIKIIFGLKEYCSGRVTIDGVDLD
Sbjct: 1141 VSVNYGETKVLKNLSFVVLGGQKIGVVGRTGAGKSTLIKIIFGLKEYCSGRVTIDGVDLD 1200

Query: 666  HISLNFRRGGMSIIPQEPVIFSGTVRENLDPFDEYDDATIWFALEQCELKRSITKEKGLN 487
            HISLNFRRGGMSIIPQEPVIFSGTVRENLDPFDEYDDATIWFALEQCELKRSITKEKGLN
Sbjct: 1201 HISLNFRRGGMSIIPQEPVIFSGTVRENLDPFDEYDDATIWFALEQCELKRSITKEKGLN 1260

Query: 486  VELGQRGVSLSVGQRQLFCLARAMIHRSKILVIDEATANVDGVTDACIQKTIRDFFKNAT 307
            VELGQRGVSLSVGQRQLFCLARAMIHRSKILVIDEATANVDGVTDACIQKTIRDFFKNAT
Sbjct: 1261 VELGQRGVSLSVGQRQLFCLARAMIHRSKILVIDEATANVDGVTDACIQKTIRDFFKNAT 1320

Query: 306  IITVAHRLHTIMNSDNVMVFEKGELVEFDKPITLLDDQSSLFSRMAAQSGAENFDSLRAA 127
            IITVAHRLHTIMNSDNVMVFEKGELVEFDKPITLLDDQSSLFSRMAAQSGAENFDSLRAA
Sbjct: 1321 IITVAHRLHTIMNSDNVMVFEKGELVEFDKPITLLDDQSSLFSRMAAQSGAENFDSLRAA 1380

Query: 126  ALAHAIDDQSSYTDNT 79
            ALAHAIDDQSSYTDN+
Sbjct: 1381 ALAHAIDDQSSYTDNS 1396


>gi|39597842|emb|CAE68534.1| Hypothetical protein CBG14361
            [Caenorhabditis briggsae]
          Length = 1257

 Score =  780 bits (2013), Expect = 0.0
 Identities = 386/532 (72%), Positives = 449/532 (83%)
 Frame = -1

Query: 1827 LNKWLVDLDMNNADNSTSKEEFNRNVDVLGYTFNVTFQTYELTFIISTVIMSILGVVRSV 1648
            + + LVDLD  NA+NST+KEEF R +  LG T+ +TF+ YE++FI+ TV +S+LGV+RSV
Sbjct: 738  MREMLVDLDEWNANNSTTKEEFYRKIAFLGVTYRITFKDYEISFIVITVTVSLLGVIRSV 797

Query: 1647 WFRNAQLMASRILHNSMFDCVLKTESEFFDKNSEGMILNRFSKDIGLTDDLLAFTYFEFV 1468
            WFR AQL ASR+LH+SMFDCVL  +SEFF++NSEG ILNRFSKDIGL DD+L+F YFEFV
Sbjct: 798  WFRYAQLNASRVLHSSMFDCVLNAQSEFFERNSEGAILNRFSKDIGLCDDMLSFCYFEFV 857

Query: 1467 FGTLTFVGIVGLVSMVRPIVILACAFITAGFYFCRKMYVHRSRELKRIEAAARSPLNTTI 1288
            FG LTF+GIVGLV+MV+PIV+ AC  IT GFY+CRK+YV RSRELKRIEAA
Sbjct: 858  FGGLTFLGIVGLVTMVKPIVLFACTLITFGFYYCRKIYVVRSRELKRIEAA--------- 908

Query: 1287 TSTVHGLSTIRAYRKENEMIEKFCALHDVYMAAYNMGLLSARWFGICIDXXXXXXXXXXX 1108
               VHGL+TIRA+RKE EM+EKFC+LHDVYMAAYNM LLSARWFGICID
Sbjct: 909  ---VHGLATIRAFRKEAEMMEKFCSLHDVYMAAYNMSLLSARWFGICIDLLVSVFISIVA 965

Query: 1107 XXXXLQYETLTVGEVGLCLVCAVQLSGFFSWIMRQSAELENGMVSVERVLEYTKLKSEEE 928
                LQYET+TVGEVGLCLVCAVQLSGFFSWIMRQSAELENGMVS+ER+LEYT+LKSEE+
Sbjct: 966  IVVVLQYETMTVGEVGLCLVCAVQLSGFFSWIMRQSAELENGMVSIERILEYTELKSEED 1025

Query: 927  ARRPHDAYLDKQLLNSWPTKGEIEFENVSVNYGETKVLKNLSFVVLGGQKIGVVGRTGAG 748
             RRPHD YLD  L N+WPTKG+IEFE+V V YGET VL NLSFV+L GQKIGVVGRTGAG
Sbjct: 1026 LRRPHDTYLDDSLKNAWPTKGQIEFEDVRVKYGETYVLNNLSFVILEGQKIGVVGRTGAG 1085

Query: 747  KSTLIKIIFGLKEYCSGRVTIDGVDLDHISLNFRRGGMSIIPQEPVIFSGTVRENLDPFD 568
            KSTLIK++FGLKEYC G+V ID  DLD ISL FRR GM+IIPQEPVIFS T+RENLDP++
Sbjct: 1086 KSTLIKVLFGLKEYCGGQVRIDDADLDSISLKFRRAGMAIIPQEPVIFSRTIRENLDPYN 1145

Query: 567  EYDDATIWFALEQCELKRSITKEKGLNVELGQRGVSLSVGQRQLFCLARAMIHRSKILVI 388
            +Y DA IW ALE+CELK +I +++GL+V LG RGV+LSVGQRQLFCLARAM+ +SKILVI
Sbjct: 1146 QYSDADIWNALEKCELKYTIARDRGLDVTLGLRGVNLSVGQRQLFCLARAMLRKSKILVI 1205

Query: 387  DEATANVDGVTDACIQKTIRDFFKNATIITVAHRLHTIMNSDNVMVFEKGEL 232
            DEATANVDGVTDACIQ+TI++ FK+AT+ITVAHRLHTIMNSD +MVFEKGEL
Sbjct: 1206 DEATANVDGVTDACIQRTIQESFKHATVITVAHRLHTIMNSDRIMVFEKGEL 1257



 Score =  754 bits (1946), Expect = 0.0
 Identities = 388/658 (58%), Positives = 479/658 (71%)
 Frame = -1

Query: 4215 LESVEGYHPSSEDSAGLISSILFSFVGFYWWRTRNAQTDTDLLEKPSKGISAKYAAQKLE 4036
            L+SVE ++PSSED+AG  S ILFS+VG YW RT++A+TD +LLEKPSK I+A +A+ +LE
Sbjct: 44   LDSVEHFYPSSEDNAGFFSGILFSYVGTYWSRTKHAKTDAELLEKPSKKITAAHASARLE 103

Query: 4035 SKWISSGPKRTHFLVGVWHCTKVSVMAHAISLCLEELTRVAQPLLLRELMSYYDIEEGQE 3856
            S W +   K  HFL GV+   + +V  HA+ LCLEELTRVAQPLLLRELMS+YD+++G+
Sbjct: 104  SAWNTPDAKGRHFLYGVYVAIRSAVFLHALLLCLEELTRVAQPLLLRELMSHYDLKDGEV 163

Query: 3855 FPYWPAMQVALIISLLSFVTVCIHHPYFHGLLKVGNHARVATGVLLYRKSLRISLTSLFE 3676
            F +W A+ VA+IIS+LSFVTV IHHPYFHGLL VGN  +V TGVLLY+K+LR+SL SL +
Sbjct: 164  FAFWSALTVAVIISVLSFVTVVIHHPYFHGLLNVGNQMKVGTGVLLYKKALRLSLGSLAD 223

Query: 3675 TNSGQIIQLLNTDAAKLEQAFLFAHYVWLCPLLMFFYAYILWSMFGFCCLLGFLVMMAIV 3496
            TNSGQIIQLLNTDAAKLEQAFLFAHYVWLCPLLMFFY +ILW  FG  CLLGF+VMM IV
Sbjct: 224  TNSGQIIQLLNTDAAKLEQAFLFAHYVWLCPLLMFFYGFILWYYFGNSCLLGFIVMMLIV 283

Query: 3495 SFQVHYSYQLGVNRRNIGDKMDSRLKVMSEIINGIKVIKMHGWENAFAEKIRILREDEIK 3316
            +FQVH+SYQLGVNR+NIGD+MD RLKVMSE+ING++VIKM  WE++FA+KI  LR+ EI
Sbjct: 284  TFQVHFSYQLGVNRKNIGDRMDDRLKVMSELINGMRVIKMICWESSFADKILELRKREIT 343

Query: 3315 AVGTSAFYSSMVMGIYFISAKIGLFVYIFACDYFDEILTTRGVFASSALFNSVXXXXXXX 3136
            AVG +++YS+MVMGIYFISAKIGLFVYIF+C Y  E L+T+ VFA+SAL+NSV
Sbjct: 344  AVGKTSYYSAMVMGIYFISAKIGLFVYIFSCLYSGEDLSTKSVFAASALYNSVRLPFALF 403

Query: 3135 XXXXXXXXXXXFSTSRRIDLFFCLEEYSRITLELDSTDTEDGSKNEKEGLTLKKIGEKPS 2956
                        STSRRI+ FF L E+SR      S D+ED S  ++E + L  +    S
Sbjct: 404  LPLGLLFGRELISTSRRINCFFKLHEFSRTP---KSRDSEDKSNVKEEKIALTSMETPAS 460

Query: 2955 WTLKCDKAEKTSVFLNKVTAVWYXXXXXXXXXXXXXXXXXXDNDATVIAGEKKDEPLHVV 2776
            W L   K +  S+ LN VT+VWY                  DN+  V   E       VV
Sbjct: 461  WILDDTKTDTPSIHLNDVTSVWYDDDEAEEQENLKELKKSDDNEEDVDTNEANPSS-SVV 519

Query: 2775 YAVQDLSFEFVAGTCYXXXXXXXXXXXXXXLTILSESRMTRGNLSVNGSFAYCAQEPWIF 2596
            Y +QD++    +G CY              LT+LSE++M++G + V+GS AYCAQEPW F
Sbjct: 520  YGIQDVTIVLKSGECYGIIGSVGSGKSSLLLTMLSEAKMSKGRMEVHGSIAYCAQEPWTF 579

Query: 2595 TGSIQDNIVFGSEFNKERYENALELCLLTPDLRQFANGDMTIVGDNGSTLSGGQXXXXXX 2416
            TG+++DNI+FG+E++ ERY+N+LELCLL  DLRQ  NGDMT+VGDNGSTLSGGQ
Sbjct: 580  TGTVRDNILFGNEYDAERYQNSLELCLLNHDLRQLQNGDMTVVGDNGSTLSGGQRARVAL 639

Query: 2415 XXXXXXXXDIYLLDDPLSAVDAHVGKKLYENLIRGFLSDKLVILVTHQIHFLSELDSV 2242
                    DIYLLDDPLSAVDAHVG+KLYENLIRGFLSDKLV+LVTHQIHFL  L+++
Sbjct: 640  ARAVYADADIYLLDDPLSAVDAHVGRKLYENLIRGFLSDKLVVLVTHQIHFLGTLNTI 697



 Score = 80.9 bits (198), Expect = 2e-13
 Identities = 56/203 (27%), Positives = 100/203 (48%), Gaps = 2/203 (0%)
 Frame = -1

Query: 843  SVNYGETKVLKNLSFVVLGGQKIGVVGRTGAGKSTLIKIIFGLKEYCSGRVTIDGVDLDH 664
            SV YG    +++++ V+  G+  G++G  G+GKS+L+  +    +   GR+ +
Sbjct: 517  SVVYG----IQDVTIVLKSGECYGIIGSVGSGKSSLLLTMLSEAKMSKGRMEV------- 565

Query: 663  ISLNFRRGGMSIIPQEPVIFSGTVRENLDPFDEYDDATIWFALEQCELKRSITK-EKGLN 487
                   G ++   QEP  F+GTVR+N+   +EYD      +LE C L   + + + G
Sbjct: 566  ------HGSIAYCAQEPWTFTGTVRDNILFGNEYDAERYQNSLELCLLNHDLRQLQNGDM 619

Query: 486  VELGQRGVSLSVGQRQLFCLARAMIHRSKILVIDEATANVDG-VTDACIQKTIRDFFKNA 310
              +G  G +LS GQR    LARA+   + I ++D+  + VD  V     +  IR F  +
Sbjct: 620  TVVGDNGSTLSGGQRARVALARAVYADADIYLLDDPLSAVDAHVGRKLYENLIRGFLSDK 679

Query: 309  TIITVAHRLHTIMNSDNVMVFEK 241
             ++ V H++H +   + +   E+
Sbjct: 680  LVVLVTHQIHFLGTLNTISASEE 702



 Score = 44.3 bits (103), Expect = 0.026
 Identities = 34/136 (25%), Positives = 62/136 (45%)
 Frame = -1

Query: 2625 AYCAQEPWIFTGSIQDNIVFGSEFNKERYENALELCLLTPDLRQFANGDMTIVGDNGSTL 2446
            A   QEP IF+ +I++N+   ++++     NALE C L   + +    D+T+ G  G  L
Sbjct: 1124 AIIPQEPVIFSRTIRENLDPYNQYSDADIWNALEKCELKYTIARDRGLDVTL-GLRGVNL 1182

Query: 2445 SGGQXXXXXXXXXXXXXXDIYLLDDPLSAVDAHVGKKLYENLIRGFLSDKLVILVTHQIH 2266
            S GQ               I ++D+  + VD  V     +  I+       VI V H++H
Sbjct: 1183 SVGQRQLFCLARAMLRKSKILVIDEATANVDG-VTDACIQRTIQESFKHATVITVAHRLH 1241

Query: 2265 FLSELDSVILMKNNKM 2218
             +   D +++ +  ++
Sbjct: 1242 TIMNSDRIMVFEKGEL 1257


>gi|26984454|emb|CAD24440.2| SI:dZ52I16.4 (novel ABC transporter
            similar to human multidrug-resistance proteins (MRP))
            [Danio rerio]
          Length = 1327

 Score =  696 bits (1796), Expect = 0.0
 Identities = 452/1400 (32%), Positives = 697/1400 (49%), Gaps = 30/1400 (2%)
 Frame = -1

Query: 4176 SAGLISSILFSFVGFYWWRTRNAQTDTDLLEKPSKGISAKYAAQKLESKWISSGPKRTHF 3997
            SA L S I F ++   +      + + D +        +K   ++L+S W     K
Sbjct: 15   SANLFSQIFFCWLNPLFSIGSKRRLEEDDMFNVLPEDRSKKLGEELQSYWDQEKEKAAKE 74

Query: 3996 LV------GVWHCTKVSVMAHAISLCLEELTRVAQPLLLRELMSYYDIEEGQEFPYWP-A 3838
            L        +  C   S     +   +EE  +V QP+ L +L+ Y++     +      A
Sbjct: 75   LKTPKLTKAIIRCYWKSYAVLGVFTLIEESIKVIQPVFLGKLIKYFENYRHDDMAALSEA 134

Query: 3837 MQVALIISLLSFVTVCIHHPYFHGLLKVGNHARVATGVLLYRKSLRISLTSLFETNSGQI 3658
               A  + L +     +HH YF+ + + G   R+A   ++YRK+L +S  ++ +T +GQI
Sbjct: 135  YGYATGVCLSTLGLALLHHLYFYHVQRAGMKIRIAMCHMIYRKALCLSAAAMGQTTTGQI 194

Query: 3657 IQLLNTDAAKLEQAFLFAHYVWLCPLLMFFYAYILWSMFGFCCLLGFLVMMAIVSFQVHY 3478
            + LL+ D  K ++  +F H++W+ PL       +LW   G  CL G  V++ ++  Q  +
Sbjct: 195  VNLLSNDVNKFDELTIFLHFLWVGPLQAAAVIGLLWQEIGPSCLAGMAVLVFLMPLQTMF 254

Query: 3477 SYQLGVNRRNIGDKMDSRLKVMSEIINGIKVIKMHGWENAFAEKIRILREDEIKAVGTSA 3298
                   R       DSR++ M+E+++GI++IKM+ WE  FA  +  +R  EI  + +S+
Sbjct: 255  GKLFSKYRSKTAALTDSRIRTMNEVVSGIRIIKMYAWEKPFAMLVNDVRRKEISKIMSSS 314

Query: 3297 FYSSMVMGIYFISAKIGLFVYIFACDYFDEILTTRGVFASSALFNSVXXXXXXXXXXXXX 3118
            +   + M  +F + KI LFV           ++   VF + +L+++V
Sbjct: 315  YLRGLNMASFFTANKIILFVTFTVYVLVGNTMSASRVFVAVSLYSAVRLTVTLFFPAAIE 374

Query: 3117 XXXXXFSTSRRIDLFFCLEEYSRITLELDSTDTEDGSKNEKEGLTLKKIGEKPSWTLKCD 2938
                   + RRI  F  L+E  +  L L        S+ EK+
Sbjct: 375  KVSESAISIRRIKKFLLLDELVKNHLPL--------SQEEKK------------------ 408

Query: 2937 KAEKTSVFLNKVTAVWYXXXXXXXXXXXXXXXXXXDNDATVIAGEKKDEPLHVVYAVQDL 2758
               + SV +  +   W                     D T+      D P      +Q++
Sbjct: 409  ---EPSVEMQDLICYW---------------------DKTL------DAP-----TLQNV 433

Query: 2757 SFEFVAGTCYXXXXXXXXXXXXXXLTILSESRMTRGNLSVNGSFAYCAQEPWIFTGSIQD 2578
             F    G                  T+L E    +G + V G   Y +Q+PW+F G+I+
Sbjct: 434  CFTVKPGQLLAVIGPVGAGKSSLLSTVLGELPAEKGVIKVKGELTYASQQPWVFPGTIRS 493

Query: 2577 NIVFGSEFNKERYENALELCLLTPDLRQFANGDMTIVGDNGSTLSGGQXXXXXXXXXXXX 2398
            NI+FG E   +RYE  L  C L  D+    +GD+T++GD G+TLSGGQ
Sbjct: 494  NILFGKELQPQRYERVLRACALKRDMELLPDGDLTVIGDRGATLSGGQKARVNLARAVYQ 553

Query: 2397 XXDIYLLDDPLSAVDAHVGKKLYENLIRGFLSDKLVILVTHQIHFLSELDSVILMKNNKM 2218
              DIYLLDDPLSAVDA V + L+E  + G L DK  ILVTHQ+ +L   + ++++K   M
Sbjct: 554  DADIYLLDDPLSAVDAEVSRHLFEQCVCGILKDKPRILVTHQLQYLKAANQILVLKEGHM 613

Query: 2217 VGNGSLDELKSTFTDDFIKLQAVETEVQSDELFVDGXXXXXXXXPVNIESMEKINKESIF 2038
            V  GS  EL+ +  D    L+  E E    E                      +++ S+
Sbjct: 614  VARGSYSELQQSGLDFTSLLKKDEEEESGSE----------KGEAPRSPRSRTVSQNSVR 663

Query: 2037 QRANSVLS---GSKMSETEYVKEIVYESRKSGTISWSVYWEYTRGVINPLKYGIWLVVCV 1867
              ++SVLS    S     E V  +  ESR  G I   +YW+Y R   N     + LV+ V
Sbjct: 664  SHSSSVLSVKDDSDQLPAEPVHTMAEESRSEGNIGIRMYWKYFRAGANV----VMLVLLV 719

Query: 1866 LITQLMNNFV---DWWLNKWLVD---LDMNNADNSTSKEEFNRNVDVLGYTFNVTFQTYE 1705
            L+  L   F    DWWL+ W  +   LD N  + +T+          L   F      Y
Sbjct: 720  LLNLLAQTFYILQDWWLSYWATEQEKLDHNTNNTNTNNTSAGNTTQQLDLNF------YL 773

Query: 1704 LTFIISTVIMSILGVVRSVWFRNAQLMASRILHNSMFDCVLKTESEFFDKNSEGMILNRF 1525
              +   T    + G +R +   NA + ++  LHN MF+ +L+T   FFD N  G ILNRF
Sbjct: 774  GIYAGLTGATIVFGFMRCLIMFNALVSSAETLHNRMFNSILRTPVRFFDINPIGRILNRF 833

Query: 1524 SKDIGLTDDLLAFTYFEFVFGTLTFVGIVGLVSMVRPIVILACAFITAGFYFCRKMYVHR 1345
            SKDIG  D LL +T+ +F+   L  VG++ + S V P +++    +   F F R+ ++
Sbjct: 834  SKDIGHLDSLLPWTFVDFIQVFLQIVGVIAVASSVIPWILIPVLPLLICFLFLRRYFLRT 893

Query: 1344 SRELKRIEAAARSPLNTTITSTVHGLSTIRAYRKENEMIEKFCALHDVYMAAYNMGLLSA 1165
            SR++KRIE+  RSP+ + ++S++ GL TIRA++ E    + F A  D++  A+ + L ++
Sbjct: 894  SRDVKRIESTTRSPVFSHLSSSLQGLWTIRAFKAEERFQQTFDAHQDLHSEAWFLFLTTS 953

Query: 1164 RWFGICIDXXXXXXXXXXXXXXXLQYETLTVGEVGLCLVCAVQLSGFFSWIMRQSAELEN 985
            RWF + +D               L  +T+  G+VGL L  AV L G F W +RQSAE+EN
Sbjct: 954  RWFAVRLDGMCSVFVTITAFGCLLLKDTMNAGDVGLALSYAVTLMGMFQWGVRQSAEVEN 1013

Query: 984  GMVSVERVLEYTKLKSE---EEARRPHDAYLDKQLLNSWPTKGEIEFENVSVNYGE--TK 820
             M SVERV+EYT+L+SE   E  +RP            WP +G I F+ V+ +Y
Sbjct: 1014 MMTSVERVVEYTELESEAPWETQKRPSP---------DWPNRGLITFDRVNFSYSSDGPV 1064

Query: 819  VLKNLSFVVLGGQKIGVVGRTGAGKSTLIKIIFGLKEYCSGRVTIDGVDLDHISLNFRRG 640
            VLKN+S +    +K+G+VGRTGAGKS+LI  +F L E   G++ +DGV    I L+  R
Sbjct: 1065 VLKNISAMFRPREKVGIVGRTGAGKSSLISALFRLSE-PEGKILVDGVLTSEIGLHDLRQ 1123

Query: 639  GMSIIPQEPVIFSGTVRENLDPFDEYDDATIWFALEQCELKRSITKEKG-LNVELGQRGV 463
             MSIIPQ+PV+F+GT+R+NLDPF+++ D  +W ALE+ +LK ++ +  G L  EL + G
Sbjct: 1124 KMSIIPQDPVLFTGTMRKNLDPFNQHSDHDLWKALEEVQLKAAVEELPGKLETELAESGS 1183

Query: 462  SLSVGQRQLFCLARAMIHRSKILVIDEATANVDGVTDACIQKTIRDFFKNATIITVAHRL 283
            + SVGQRQL CLARA++ ++++L+IDEATANVD  TD  IQKTIRD FK  T++T+AHRL
Sbjct: 1184 NFSVGQRQLVCLARAILRKNRVLIIDEATANVDPRTDELIQKTIRDKFKECTVLTIAHRL 1243

Query: 282  HTIMNSDNVMVFEKGELVEFDKPITLLDDQSSLFSRMAAQSGAENFDSLRAAAL------ 121
            +TI++SD ++V + G + E+D P  LL +QS +F +M  Q+G     SL   A
Sbjct: 1244 NTIIDSDRILVLDAGRIHEYDAPHVLLQNQSGIFYKMVQQTGKAEATSLLQTAKQAYTNR 1303

Query: 120  --AHAIDDQSSYTDNTIQLF 67
              AH ++  ++  D ++ +F
Sbjct: 1304 SPAHQLNGFATTGDGSLIIF 1323


>gi|31322321|gb|AAO37649.1| ATP-binding cassette transporter C4 [Homo
            sapiens]
          Length = 1325

 Score =  684 bits (1764), Expect = 0.0
 Identities = 435/1303 (33%), Positives = 675/1303 (51%), Gaps = 18/1303 (1%)
 Frame = -1

Query: 3978 CTKVSVMAHAISLCLEELTRVAQPLLLRELMSYYDIEEGQE-FPYWPAMQVALIISLLSF 3802
            C   S +   I   +EE  +V QP+ L ++++Y++  +  +      A   A +++  +
Sbjct: 87   CYWKSYLVLGIFTLIEESAKVIQPIFLGKIINYFENYDPMDSVALNTAYAYATVLTFCTL 146

Query: 3801 VTVCIHHPYFHGLLKVGNHARVATGVLLYRKSLRISLTSLFETNSGQIIQLLNTDAAKLE 3622
            +   +HH YF+ +   G   RVA   ++YRK+LR+S  ++ +T +GQI+ LL+ D  K +
Sbjct: 147  ILAILHHLYFYHVQCAGMRLRVAMCHMIYRKALRLSNMAMGKTTTGQIVNLLSNDVNKFD 206

Query: 3621 QAFLFAHYVWLCPLLMFFYAYILWSMFGFCCLLGFLVMMAIVSFQVHYSYQLGVNRRNIG 3442
            Q  +F H++W  PL       +LW   G  CL G  V++ ++  Q  +       R
Sbjct: 207  QVTVFLHFLWAGPLQAIAVTALLWMEIGISCLAGMAVLIILLPLQSCFGKLFSSLRSKTA 266

Query: 3441 DKMDSRLKVMSEIINGIKVIKMHGWENAFAEKIRILREDEIKAVGTSAFYSSMVMGIYFI 3262
               D+R++ M+E+I GI++IKM+ WE +F+  I  LR+ EI  +  S+    M +  +F
Sbjct: 267  TFTDARIRTMNEVITGIRIIKMYAWEKSFSNLITNLRKKEISKILRSSCLRGMNLASFFS 326

Query: 3261 SAKIGLFVYIFACDYFDEILTTRGVFASSALFNSVXXXXXXXXXXXXXXXXXXFSTSRRI 3082
            ++KI +FV          ++T   VF +  L+ +V                    + RRI
Sbjct: 327  ASKIIVFVTFTTYVLLGSVITASRVFVAVTLYGAVRLTVTLFFPSAIERVSEAIVSIRRI 386

Query: 3081 DLFFCLEEYSRITLELDSTDTEDGSKNEKEGLTLKKIGEKPSWTLKCDKAEKTSVFLNKV 2902
              F  L+E S+   +L S    DG          KK+     +T   DKA +T
Sbjct: 387  QTFLLLDEISQRNRQLPS----DG----------KKMVHVQDFTAFWDKASETPT----- 427

Query: 2901 TAVWYXXXXXXXXXXXXXXXXXXDNDATVIAGEKKDEPLHVVYAVQDLSFEFVAGTCYXX 2722
                                                        +Q LSF    G
Sbjct: 428  --------------------------------------------LQGLSFTVRPGELLAV 443

Query: 2721 XXXXXXXXXXXXLTILSESRMTRGNLSVNGSFAYCAQEPWIFTGSIQDNIVFGSEFNKER 2542
                          +L E   + G +SV+G  AY +Q+PW+F+G+++ NI+FG ++ KER
Sbjct: 444  VGPVGAGKSSLLSAVLGELAPSHGLVSVHGRIAYVSQQPWVFSGTLRSNILFGKKYEKER 503

Query: 2541 YENALELCLLTPDLRQFANGDMTIVGDNGSTLSGGQXXXXXXXXXXXXXXDIYLLDDPLS 2362
            YE  ++ C L  DL+   +GD+T++GD G+TLSGGQ              DIYLLDDPLS
Sbjct: 504  YEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADIYLLDDPLS 563

Query: 2361 AVDAHVGKKLYENLIRGFLSDKLVILVTHQIHFLSELDSVILMKNNKMVGNGSLDE-LKS 2185
            AVDA V + L+E  I   L +K+ ILVTHQ+ +L     ++++K+ KMV  G+  E LKS
Sbjct: 564  AVDAEVSRHLFELCICQILHEKITILVTHQLQYLKAASQILILKDGKMVQKGTYTEFLKS 623

Query: 2184 TFTDDFIKLQAVETEVQSDELFVDGXXXXXXXXPVNIESMEKINKESIFQRANSVLS--- 2014
                DF  L   + E +S++  V G                  ++ S++ + +S  S
Sbjct: 624  GI--DFGSLLKKDNE-ESEQPPVPGTPTLRN---------RTFSESSVWSQQSSRPSLKD 671

Query: 2013 -GSKMSETEYVK-EIVYESRKSGTISWSVYWEYTRGVINPLKYGIWLVVCVLITQLMNNF 1840
               +  +TE V   +  E+R  G + +  Y  Y R   + + + I+L++     Q+
Sbjct: 672  GALESQDTENVPVTLSEENRSEGKVGFQAYKNYFRAGAHWIVF-IFLILLNTAAQVAYVL 730

Query: 1839 VDWWLNKW-----LVDLDMNNADNSTSKEEFNRNVDVLGYTFNVTFQTYELTFIISTVIM 1675
             DWWL+ W     ++++ +N   N T K + N  + +               +   TV
Sbjct: 731  QDWWLSYWANKQSMLNVTVNGGGNVTEKLDLNWYLGI---------------YSGLTVAT 775

Query: 1674 SILGVVRSVWFRNAQLMASRILHNSMFDCVLKTESEFFDKNSEGMILNRFSKDIGLTDDL 1495
             + G+ RS+      + +S+ LHN MF+ +LK    FFD+N  G ILNRFSKDIG  DDL
Sbjct: 776  VLFGIARSLLVFYVLVNSSQTLHNKMFESILKAPVLFFDRNPIGRILNRFSKDIGHLDDL 835

Query: 1494 LAFTYFEFVFGTLTFVGIVGLVSMVRPIVILACAFITAGFYFCRKMYVHRSRELKRIEAA 1315
            L  T+ +F+   L  VG+V +   V P + +    +   F F R+ ++  SR++KR+E+
Sbjct: 836  LPLTFLDFIQTLLQVVGVVSVAVAVIPWIAIPLVPLGIIFIFLRRYFLETSRDVKRLEST 895

Query: 1314 ARSPLNTTITSTVHGLSTIRAYRKENEMIEKFCALHDVYMAAYNMGLLSARWFGICIDXX 1135
             RSP+ + ++S++ GL TIRAY+ E    E F A  D++  A+ + L ++RWF + +D
Sbjct: 896  TRSPVFSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAI 955

Query: 1134 XXXXXXXXXXXXXLQYETLTVGEVGLCLVCAVQLSGFFSWIMRQSAELENGMVSVERVLE 955
                         +  +TL  G+VGL L  A+ L G F W +RQSAE+EN M+SVERV+E
Sbjct: 956  CAMFVIIVAFGSLILAKTLDAGQVGLALSYALTLMGMFQWCVRQSAEVENMMISVERVIE 1015

Query: 954  YTKLKSE---EEARRPHDAYLDKQLLNSWPTKGEIEFENVSVNY--GETKVLKNLSFVVL 790
            YT L+ E   E  +RP  A         WP +G I F+NV+  Y  G   VLK+L+ ++
Sbjct: 1016 YTDLEKEAPWEYQKRPPPA---------WPHEGVIIFDNVNFMYSPGGPLVLKHLTALIK 1066

Query: 789  GGQKIGVVGRTGAGKSTLIKIIFGLKEYCSGRVTIDGVDLDHISLNFRRGGMSIIPQEPV 610
              +K+G+VGRTGAGKS+LI  +F L E   G++ ID +    I L+  R  MSIIPQEPV
Sbjct: 1067 SQEKVGIVGRTGAGKSSLISALFRLSE-PEGKIWIDKILTTEIGLHDLRKKMSIIPQEPV 1125

Query: 609  IFSGTVRENLDPFDEYDDATIWFALEQCELKRSITKEKG-LNVELGQRGVSLSVGQRQLF 433
            +F+GT+R+NLDPF+E+ D  +W AL++ +LK +I    G ++ EL + G + SVGQRQL
Sbjct: 1126 LFTGTMRKNLDPFNEHTDEELWNALQEVQLKETIEDLPGKMDTELAESGSNFSVGQRQLV 1185

Query: 432  CLARAMIHRSKILVIDEATANVDGVTDACIQKTIRDFFKNATIITVAHRLHTIMNSDNVM 253
            CLARA++ +++IL+IDEATANVD  TD  IQK IR+ F + T++T+AHRL+TI++SD +M
Sbjct: 1186 CLARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIAHRLNTIIDSDKIM 1245

Query: 252  VFEKGELVEFDKPITLLDDQSSLFSRMAAQSGAENFDSLRAAA 124
            V + G L E+D+P  LL ++ SLF +M  Q G     +L   A
Sbjct: 1246 VLDSGRLKEYDEPYVLLQNKESLFYKMVQQLGKAEAAALTETA 1288


>gi|5031915|ref|NP_005836.1| ATP-binding cassette, sub-family C,
            member 4; canalicular multispecific organic anion
            transporter (ABC superfamily) [Homo sapiens]
 gi|8928546|sp|O15439|MRP4_HUMAN Multidrug resistance-associated
            protein 4 (MRP/cMOAT-related ABC transporter)
            (Multi-specific organic anion tranporter-B) (MOAT-B)
 gi|3335173|gb|AAC27076.1| ABC transporter MOAT-B [Homo sapiens]
          Length = 1325

 Score =  683 bits (1762), Expect = 0.0
 Identities = 435/1303 (33%), Positives = 674/1303 (51%), Gaps = 18/1303 (1%)
 Frame = -1

Query: 3978 CTKVSVMAHAISLCLEELTRVAQPLLLRELMSYYDIEEGQE-FPYWPAMQVALIISLLSF 3802
            C   S +   I   +EE  +V QP+ L ++++Y++  +  +      A   A +++  +
Sbjct: 87   CYWKSYLVLGIFTLIEESAKVIQPIFLGKIINYFENYDPMDSVALNTAYAYATVLTFCTL 146

Query: 3801 VTVCIHHPYFHGLLKVGNHARVATGVLLYRKSLRISLTSLFETNSGQIIQLLNTDAAKLE 3622
            +   +HH YF+ +   G   RVA   ++YRK+LR+S  ++ +T +GQI+ LL+ D  K +
Sbjct: 147  ILAILHHLYFYHVQCAGMRLRVAMCHMIYRKALRLSNMAMGKTTTGQIVNLLSNDVNKFD 206

Query: 3621 QAFLFAHYVWLCPLLMFFYAYILWSMFGFCCLLGFLVMMAIVSFQVHYSYQLGVNRRNIG 3442
            Q  +F H++W  PL       +LW   G  CL G  V++ ++  Q  +       R
Sbjct: 207  QVTVFLHFLWAGPLQAIAVTALLWMEIGISCLAGMAVLIILLPLQSCFGKLFSSLRSKTA 266

Query: 3441 DKMDSRLKVMSEIINGIKVIKMHGWENAFAEKIRILREDEIKAVGTSAFYSSMVMGIYFI 3262
               D+R++ M+E+I GI++IKM+ WE +F+  I  LR+ EI  +  S+    M +  +F
Sbjct: 267  TFTDARIRTMNEVITGIRIIKMYAWEKSFSNLITNLRKKEISKILRSSCLRGMNLASFFS 326

Query: 3261 SAKIGLFVYIFACDYFDEILTTRGVFASSALFNSVXXXXXXXXXXXXXXXXXXFSTSRRI 3082
            ++KI +FV          ++T   VF +  L+ +V                    + RRI
Sbjct: 327  ASKIIVFVTFTTYVLLGSVITASRVFVAVTLYGAVRLTVTLFFPSAIERVSEAIVSIRRI 386

Query: 3081 DLFFCLEEYSRITLELDSTDTEDGSKNEKEGLTLKKIGEKPSWTLKCDKAEKTSVFLNKV 2902
              F  L+E S+   +L S    DG          KK+     +T   DKA +T
Sbjct: 387  QTFLLLDEISQRNRQLPS----DG----------KKMVHVQDFTAFWDKASETPT----- 427

Query: 2901 TAVWYXXXXXXXXXXXXXXXXXXDNDATVIAGEKKDEPLHVVYAVQDLSFEFVAGTCYXX 2722
                                                        +Q LSF    G
Sbjct: 428  --------------------------------------------LQGLSFTVRPGELLAV 443

Query: 2721 XXXXXXXXXXXXLTILSESRMTRGNLSVNGSFAYCAQEPWIFTGSIQDNIVFGSEFNKER 2542
                          +L E   + G +SV+G  AY +Q+PW+F+G+++ NI+FG ++ KER
Sbjct: 444  VGPVGAGKSSLLSAVLGELAPSHGLVSVHGRIAYVSQQPWVFSGTLRSNILFGKKYEKER 503

Query: 2541 YENALELCLLTPDLRQFANGDMTIVGDNGSTLSGGQXXXXXXXXXXXXXXDIYLLDDPLS 2362
            YE  ++ C L  DL+   +GD+T++GD G+TLSGGQ              DIYLLDDPLS
Sbjct: 504  YEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADIYLLDDPLS 563

Query: 2361 AVDAHVGKKLYENLIRGFLSDKLVILVTHQIHFLSELDSVILMKNNKMVGNGSLDE-LKS 2185
            AVDA V + L+E  I   L +K+ ILVTHQ+ +L     ++++K+ KMV  G+  E LKS
Sbjct: 564  AVDAEVSRHLFELCICQILHEKITILVTHQLQYLKAASQILILKDGKMVQKGTYTEFLKS 623

Query: 2184 TFTDDFIKLQAVETEVQSDELFVDGXXXXXXXXPVNIESMEKINKESIFQRANSVLS--- 2014
                DF  L   + E +S++  V G                  ++ S++ + +S  S
Sbjct: 624  GI--DFGSLLKKDNE-ESEQPPVPGTPTLRN---------RTFSESSVWSQQSSRPSLKD 671

Query: 2013 -GSKMSETEYVK-EIVYESRKSGTISWSVYWEYTRGVINPLKYGIWLVVCVLITQLMNNF 1840
               +  +TE V   +  E+R  G + +  Y  Y R   + + + I+L++     Q+
Sbjct: 672  GALESQDTENVPVTLSEENRSEGKVGFQAYKNYFRAGAHWIVF-IFLILLNTAAQVAYVL 730

Query: 1839 VDWWLNKW-----LVDLDMNNADNSTSKEEFNRNVDVLGYTFNVTFQTYELTFIISTVIM 1675
             DWWL+ W     ++++ +N   N T K + N  + +               +   TV
Sbjct: 731  QDWWLSYWANKQSMLNVTVNGGGNVTEKLDLNWYLGI---------------YSGLTVAT 775

Query: 1674 SILGVVRSVWFRNAQLMASRILHNSMFDCVLKTESEFFDKNSEGMILNRFSKDIGLTDDL 1495
             + G+ RS+      + +S+ LHN MF+ +LK    FFD+N  G ILNRFSKDIG  DDL
Sbjct: 776  VLFGIARSLLVFYVLVNSSQTLHNKMFESILKAPVLFFDRNPIGRILNRFSKDIGHLDDL 835

Query: 1494 LAFTYFEFVFGTLTFVGIVGLVSMVRPIVILACAFITAGFYFCRKMYVHRSRELKRIEAA 1315
            L  T+ +F+   L  VG+V +   V P + +    +   F F R+ ++  SR++KR+E+
Sbjct: 836  LPLTFLDFIQTLLQVVGVVSVAVAVIPWIAIPLVPLGIIFIFLRRYFLETSRDVKRLEST 895

Query: 1314 ARSPLNTTITSTVHGLSTIRAYRKENEMIEKFCALHDVYMAAYNMGLLSARWFGICIDXX 1135
             RSP+ + ++S++ GL TIRAY+ E    E F A  D++  A+ + L ++RWF + +D
Sbjct: 896  TRSPVFSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAI 955

Query: 1134 XXXXXXXXXXXXXLQYETLTVGEVGLCLVCAVQLSGFFSWIMRQSAELENGMVSVERVLE 955
                         +  +TL  G+VGL L  A+ L G F W +RQSAE+EN M+SVERV+E
Sbjct: 956  CAMFVIIVAFGSLILAKTLDAGQVGLALSYALTLMGMFQWCVRQSAEVENMMISVERVIE 1015

Query: 954  YTKLKSE---EEARRPHDAYLDKQLLNSWPTKGEIEFENVSVNY--GETKVLKNLSFVVL 790
            YT L+ E   E  +RP  A         WP +G I F+NV+  Y  G   VLK+L+ ++
Sbjct: 1016 YTDLEKEAPWEYQKRPPPA---------WPHEGVIIFDNVNFMYSPGGPLVLKHLTALIK 1066

Query: 789  GGQKIGVVGRTGAGKSTLIKIIFGLKEYCSGRVTIDGVDLDHISLNFRRGGMSIIPQEPV 610
              +K+G+VGRTGAGKS+LI  +F L E   G++ ID +    I L+  R  MSIIPQEPV
Sbjct: 1067 SQEKVGIVGRTGAGKSSLISALFRLSE-PEGKIWIDKILTTEIGLHDLRKKMSIIPQEPV 1125

Query: 609  IFSGTVRENLDPFDEYDDATIWFALEQCELKRSITKEKG-LNVELGQRGVSLSVGQRQLF 433
            +F+GT+R+NLDPF E+ D  +W AL++ +LK +I    G ++ EL + G + SVGQRQL
Sbjct: 1126 LFTGTMRKNLDPFKEHTDEELWNALQEVQLKETIEDLPGKMDTELAESGSNFSVGQRQLV 1185

Query: 432  CLARAMIHRSKILVIDEATANVDGVTDACIQKTIRDFFKNATIITVAHRLHTIMNSDNVM 253
            CLARA++ +++IL+IDEATANVD  TD  IQK IR+ F + T++T+AHRL+TI++SD +M
Sbjct: 1186 CLARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIAHRLNTIIDSDKIM 1245

Query: 252  VFEKGELVEFDKPITLLDDQSSLFSRMAAQSGAENFDSLRAAA 124
            V + G L E+D+P  LL ++ SLF +M  Q G     +L   A
Sbjct: 1246 VLDSGRLKEYDEPYVLLQNKESLFYKMVQQLGKAEAAALTETA 1288


>gi|21655123|gb|AAL88745.1| multidrug resistance-associated protein
            [Homo sapiens]
          Length = 1325

 Score =  681 bits (1757), Expect = 0.0
 Identities = 434/1303 (33%), Positives = 674/1303 (51%), Gaps = 18/1303 (1%)
 Frame = -1

Query: 3978 CTKVSVMAHAISLCLEELTRVAQPLLLRELMSYYDIEEGQE-FPYWPAMQVALIISLLSF 3802
            C   S +   I   +EE  +V QP+ L ++++Y++  +  +      A   A +++  +
Sbjct: 87   CYWKSYLVLGIFTLIEESAKVIQPIFLGKIINYFENYDPMDSVALNTAYAYATVLTFCTL 146

Query: 3801 VTVCIHHPYFHGLLKVGNHARVATGVLLYRKSLRISLTSLFETNSGQIIQLLNTDAAKLE 3622
            +   +HH YF+ +   G   RVA   ++YRK+LR+S  ++ +T +GQI+ LL+ D  K +
Sbjct: 147  ILAILHHLYFYHVQCAGMRLRVAMCHMIYRKALRLSNMAMGKTTTGQIVNLLSNDVNKFD 206

Query: 3621 QAFLFAHYVWLCPLLMFFYAYILWSMFGFCCLLGFLVMMAIVSFQVHYSYQLGVNRRNIG 3442
            Q  +F H++W  PL       +LW   G  CL G  V++ ++  Q  +       R
Sbjct: 207  QVTVFLHFLWAGPLQAIAVTALLWMEIGISCLAGMAVLIILLPLQSCFGKLFSSLRSKTA 266

Query: 3441 DKMDSRLKVMSEIINGIKVIKMHGWENAFAEKIRILREDEIKAVGTSAFYSSMVMGIYFI 3262
               D+R++ M+E+I GI++IKM+ WE +F+  I  LR+ EI  +  S+    M +  +F
Sbjct: 267  TFTDARIRTMNEVITGIRIIKMYAWEKSFSNLITNLRKKEISKILRSSCLRGMNLASFFS 326

Query: 3261 SAKIGLFVYIFACDYFDEILTTRGVFASSALFNSVXXXXXXXXXXXXXXXXXXFSTSRRI 3082
            ++KI +FV          ++T   VF +  L+ +V                    + RRI
Sbjct: 327  ASKIIVFVTFTTYVLLGSVITASRVFVAVTLYGAVRLTVTLFFPSAIERVSEAIVSIRRI 386

Query: 3081 DLFFCLEEYSRITLELDSTDTEDGSKNEKEGLTLKKIGEKPSWTLKCDKAEKTSVFLNKV 2902
              F  L+E S+   +L S    DG          KK+     +T   DKA +T
Sbjct: 387  QTFLLLDEISQRNRQLPS----DG----------KKMVHVQDFTAFWDKASETPT----- 427

Query: 2901 TAVWYXXXXXXXXXXXXXXXXXXDNDATVIAGEKKDEPLHVVYAVQDLSFEFVAGTCYXX 2722
                                                        +Q LSF    G
Sbjct: 428  --------------------------------------------LQGLSFTVRPGELLAV 443

Query: 2721 XXXXXXXXXXXXLTILSESRMTRGNLSVNGSFAYCAQEPWIFTGSIQDNIVFGSEFNKER 2542
                          +L E   + G +SV+G  AY +Q+PW+F+G+++ NI+FG ++ KER
Sbjct: 444  VGPVGAGKSSLLSAVLGELAPSHGLVSVHGRIAYVSQQPWVFSGTLRSNILFGKKYEKER 503

Query: 2541 YENALELCLLTPDLRQFANGDMTIVGDNGSTLSGGQXXXXXXXXXXXXXXDIYLLDDPLS 2362
            YE  ++ C L  DL+   +GD+T++GD G+TLSGGQ              DIYLLDDPLS
Sbjct: 504  YEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADIYLLDDPLS 563

Query: 2361 AVDAHVGKKLYENLIRGFLSDKLVILVTHQIHFLSELDSVILMKNNKMVGNGSLDE-LKS 2185
            AVDA V + L+E  I   L +K+ ILVTHQ+ +L     ++++K+ KMV  G+  E LKS
Sbjct: 564  AVDAEVSRHLFELCICQILHEKITILVTHQLQYLKAASQILILKDGKMVQKGTYTEFLKS 623

Query: 2184 TFTDDFIKLQAVETEVQSDELFVDGXXXXXXXXPVNIESMEKINKESIFQRANSVLS--- 2014
                DF  L   + E +S++  V G                  ++ S++ + +S  S
Sbjct: 624  GI--DFGSLLKKDNE-ESEQPPVPGTPTLRN---------RTFSESSVWSQQSSRPSLKD 671

Query: 2013 -GSKMSETEYVK-EIVYESRKSGTISWSVYWEYTRGVINPLKYGIWLVVCVLITQLMNNF 1840
               +  +TE V   +  E+R  G + +  Y  Y R   + + + I+L++     Q+
Sbjct: 672  GALESQDTENVPVTLSEENRSEGKVGFQAYKSYFRAGAHWIVF-IFLILLNTAAQVAYVL 730

Query: 1839 VDWWLNKW-----LVDLDMNNADNSTSKEEFNRNVDVLGYTFNVTFQTYELTFIISTVIM 1675
             DWWL+ W     ++++ +N   N T K + N  + +               +   TV
Sbjct: 731  QDWWLSYWANKQSMLNVTVNGGGNVTGKLDLNWYLGI---------------YSGLTVAT 775

Query: 1674 SILGVVRSVWFRNAQLMASRILHNSMFDCVLKTESEFFDKNSEGMILNRFSKDIGLTDDL 1495
             + G+ RS+      + +S+ LHN MF+ +LK    FFD+N  G ILNRFSKDIG  DDL
Sbjct: 776  VLFGIARSLLVFYVLVNSSQTLHNKMFESILKAPVLFFDRNPIGRILNRFSKDIGHLDDL 835

Query: 1494 LAFTYFEFVFGTLTFVGIVGLVSMVRPIVILACAFITAGFYFCRKMYVHRSRELKRIEAA 1315
            L  T+ +F+   L  VG+V +   V P + +    +   F F R+ ++  SR++KR+ +
Sbjct: 836  LPLTFLDFIQTLLQVVGVVSVAVAVIPWIAIPLVPLGIIFIFLRRYFLETSRDVKRLGST 895

Query: 1314 ARSPLNTTITSTVHGLSTIRAYRKENEMIEKFCALHDVYMAAYNMGLLSARWFGICIDXX 1135
             RSP+ + ++S++ GL TIRAY+ E    E F A  D++  A+ + L ++RWF + +D
Sbjct: 896  TRSPVFSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAI 955

Query: 1134 XXXXXXXXXXXXXLQYETLTVGEVGLCLVCAVQLSGFFSWIMRQSAELENGMVSVERVLE 955
                         +  +TL  G+VGL L  A+ L G F W +RQSAE+EN M+SVERV+E
Sbjct: 956  CAMFVIIVAFGSLILAKTLDAGQVGLALSYALTLMGMFQWCVRQSAEVENMMISVERVIE 1015

Query: 954  YTKLKSE---EEARRPHDAYLDKQLLNSWPTKGEIEFENVSVNY--GETKVLKNLSFVVL 790
            YT L+ E   E  +RP  A         WP +G I F+NV+  Y  G   VLK+L+ ++
Sbjct: 1016 YTDLEKEAPWEYQKRPPPA---------WPHEGVIIFDNVNFMYSPGGPLVLKHLTALIK 1066

Query: 789  GGQKIGVVGRTGAGKSTLIKIIFGLKEYCSGRVTIDGVDLDHISLNFRRGGMSIIPQEPV 610
              +K+G+VGRTGAGKS+LI  +F L E   G++ ID +    I L+  R  MSIIPQEPV
Sbjct: 1067 SQEKVGIVGRTGAGKSSLISALFRLSE-PEGKIWIDKILTTEIGLHDLRKKMSIIPQEPV 1125

Query: 609  IFSGTVRENLDPFDEYDDATIWFALEQCELKRSITKEKG-LNVELGQRGVSLSVGQRQLF 433
            +F+GT+R+NLDPF+E+ D  +W AL++ +LK +I    G ++ EL + G + SVGQRQL
Sbjct: 1126 LFTGTMRKNLDPFNEHTDEELWNALQEVQLKETIEDLPGKMDTELAESGSNFSVGQRQLV 1185

Query: 432  CLARAMIHRSKILVIDEATANVDGVTDACIQKTIRDFFKNATIITVAHRLHTIMNSDNVM 253
            CLARA++ +++IL+IDEATANVD  TD  IQK IR+ F + T++T+AHRL+TI++SD +M
Sbjct: 1186 CLARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIAHRLNTIIDSDKIM 1245

Query: 252  VFEKGELVEFDKPITLLDDQSSLFSRMAAQSGAENFDSLRAAA 124
            V + G L E+D+P  LL ++ SLF +M  Q G     +L   A
Sbjct: 1246 VLDSGRLKEYDEPYVLLQNKESLFYKMVQQLGKAEAAALTETA 1288


>gi|45862332|gb|AAS78928.1| multidrug resistance-associated protein 4
            [Rattus norvegicus]
          Length = 1325

 Score =  679 bits (1753), Expect = 0.0
 Identities = 438/1347 (32%), Positives = 676/1347 (49%), Gaps = 21/1347 (1%)
 Frame = -1

Query: 4134 FYWW--------RTRNAQTDTDLLEKPSKGISAKYAAQKLESKW------ISSGPKRTHF 3997
            F+WW          R  + D      P     +K+  ++L+  W           ++
Sbjct: 23   FFWWLNPLFKAGHKRRLEEDDMFSVLPED--RSKHLGEELQGYWDKEVLRAKKDARKPSL 80

Query: 3996 LVGVWHCTKVSVMAHAISLCLEELTRVAQPLLLRELMSYYD-IEEGQEFPYWPAMQVALI 3820
               +  C   S +   I   +EE TRV QP+ L +++ Y++  +         A   A +
Sbjct: 81   TKAIVKCYWKSYLILGIFTLIEETTRVVQPIFLGKIIDYFEKYDSDDSAALHTAYGYAAV 140

Query: 3819 ISLLSFVTVCIHHPYFHGLLKVGNHARVATGVLLYRKSLRISLTSLFETNSGQIIQLLNT 3640
            +SL + +   +HH YF+ +   G   RVA   ++YRK+LR+S +++ +T +GQI+ LL+
Sbjct: 141  LSLCTLILAILHHLYFYHVQCAGMRIRVAMCHMIYRKALRLSNSAMGKTTTGQIVNLLSN 200

Query: 3639 DAAKLEQAFLFAHYVWLCPLLMFFYAYILWSMFGFCCLLGFLVMMAIVSFQVHYSYQLGV 3460
            D  K +Q  +F H++W  PL       +LW   G  CL G  +++ ++  Q
Sbjct: 201  DVNKFDQVTIFLHFLWAGPLQAIGVTILLWVEIGISCLAGLAILVILLPLQSCIGKLFSS 260

Query: 3459 NRRNIGDKMDSRLKVMSEIINGIKVIKMHGWENAFAEKIRILREDEIKAVGTSAFYSSMV 3280
             R       D+R + M+E+I G+++IKM+ WE +FA+ I  LR+ EI  +  S++   M
Sbjct: 261  LRSKTAAFTDARFRTMNEVITGMRIIKMYAWEKSFADLITNLRKKEISKILGSSYLRGMN 320

Query: 3279 MGIYFISAKIGLFVYIFACDYFDEILTTRGVFASSALFNSVXXXXXXXXXXXXXXXXXXF 3100
            M  +FI+ K+ LFV           +T+  VF +  L+ +V
Sbjct: 321  MASFFIANKVILFVTFTTYVLLGNKITSSHVFVAMTLYGAVRLTVTLFFPSAIERVSEAV 380

Query: 3099 STSRRIDLFFCLEEYSRITLELDSTDTEDGSKNEKEGLTLKKIGEKPSWTLKCDKAEKTS 2920
             + RRI  F  L+E      E  + +  DG                           K
Sbjct: 381  VSVRRIKNFLLLDELP----ERKAQEPSDG---------------------------KAI 409

Query: 2919 VFLNKVTAVWYXXXXXXXXXXXXXXXXXXDNDATVIAGEKKDEPLHVVYAVQDLSFEFVA 2740
            V +   TA W                            +  D P      +Q LSF
Sbjct: 410  VHVQDFTAFW---------------------------DKALDTP-----TLQGLSFTARP 437

Query: 2739 GTCYXXXXXXXXXXXXXXLTILSESRMTRGNLSVNGSFAYCAQEPWIFTGSIQDNIVFGS 2560
            G                   +L E   T G +SV+G  AY +Q+PW+F+G+++ NI+FG
Sbjct: 438  GELLAVVGPVGAGKSSLLSAVLGELPPTSGLVSVHGRIAYVSQQPWVFSGTVRSNILFGR 497

Query: 2559 EFNKERYENALELCLLTPDLRQFANGDMTIVGDNGSTLSGGQXXXXXXXXXXXXXXDIYL 2380
            ++ KERYE  ++ C L  DL+   +GD+T++GD G+TLSGGQ              DIYL
Sbjct: 498  KYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGATLSGGQKARVNLARAVYQDADIYL 557

Query: 2379 LDDPLSAVDAHVGKKLYENLIRGFLSDKLVILVTHQIHFLSELDSVILMKNNKMVGNGSL 2200
            LDDPLSAVDA VGK L++  I   L +K+ ILVTHQ+ +L     ++++K+ +MV  G+
Sbjct: 558  LDDPLSAVDAEVGKHLFQLCICQTLHEKITILVTHQLQYLKAASHILILKDGEMVQKGTY 617

Query: 2199 DELKSTFTDDFIKLQAVETEVQSDELFVDGXXXXXXXXPVNIESMEKINKESIFQRANSV 2020
             E   +  D    L+    E +   +              +I S +  ++ S+    + V
Sbjct: 618  TEFLKSGVDFGSLLKKENEEAEPSPVPGTPTLRNRTFSEASIWSQQS-SRPSL---KDGV 673

Query: 2019 LSGSKMSETEYVKEIVYESRKSGTISWSVYWEYTRGVINPLKYGIWLVVCVLITQLMNNF 1840
                    T+  +    ESR  G I +  Y  Y     +   + I+LV+  L+ Q+
Sbjct: 674  PDAQDAENTQAAQP--EESRSEGRIGFKAYKNYFSAGASWF-FIIFLVLLNLMGQVFYVL 730

Query: 1839 VDWWLNKWLVDLDMNNADNSTSKEEFNRNVDVLGYTFNVTFQTYELTFIISTVIMSILGV 1660
             DWWL+ W    +   A N T     N N +V G    +    Y   +   T +  + G+
Sbjct: 731  QDWWLSHWA---NRQGALNDTK----NANGNVTG---TLDLSWYLGIYTGLTAVTVLFGI 780

Query: 1659 VRSVWFRNAQLMASRILHNSMFDCVLKTESEFFDKNSEGMILNRFSKDIGLTDDLLAFTY 1480
             RS+      + AS+ LHN MF+ +LK    FFD+N  G ILNRFSKDIG  DDLL  T+
Sbjct: 781  ARSLLVFYVLVNASQTLHNRMFESILKAPVLFFDRNPIGRILNRFSKDIGHMDDLLPLTF 840

Query: 1479 FEFVFGTLTFVGIVGLVSMVRPIVILACAFITAGFYFCRKMYVHRSRELKRIEAAARSPL 1300
             +F+   L  V ++ + + V P +++    ++  F   R+ ++  SR++KR+E+  RSP+
Sbjct: 841  LDFIQTLLLVVSVIAVAAAVIPWILIPLVPLSIIFVVLRRYFLETSRDVKRLESTTRSPV 900

Query: 1299 NTTITSTVHGLSTIRAYRKENEMIEKFCALHDVYMAAYNMGLLSARWFGICIDXXXXXXX 1120
             + ++S++ GL TIRAY+ E    E F A  D++  A+ + L ++RWF + +D
Sbjct: 901  FSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAVFV 960

Query: 1119 XXXXXXXXLQYETLTVGEVGLCLVCAVQLSGFFSWIMRQSAELENGMVSVERVLEYTKLK 940
                    +  +TL  G+VGL L  ++ L G F W +RQSAE+EN M+SVERV+EYT L+
Sbjct: 961  IVVAFGSLVLAKTLDAGQVGLALSYSLTLMGMFQWSVRQSAEVENMMISVERVIEYTDLE 1020

Query: 939  SE---EEARRPHDAYLDKQLLNSWPTKGEIEFENVSVNYG--ETKVLKNLSFVVLGGQKI 775
             E   E  +RP            WP +G I F+NV+  Y      VLK+L+ ++   +K+
Sbjct: 1021 KEAPWECRKRPPP---------GWPHEGVIVFDNVNFTYSLDGPLVLKHLTALIKSREKV 1071

Query: 774  GVVGRTGAGKSTLIKIIFGLKEYCSGRVTIDGVDLDHISLNFRRGGMSIIPQEPVIFSGT 595
            G+VGRTGAGKS+LI  +F L E   G++ ID +    I L+  R  MSIIPQEPV+F+GT
Sbjct: 1072 GIVGRTGAGKSSLISALFRLSE-PEGKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGT 1130

Query: 594  VRENLDPFDEYDDATIWFALEQCELKRSITKEKG-LNVELGQRGVSLSVGQRQLFCLARA 418
            +R+NLDPF+E+ D  +W ALE+ +LK +I    G ++ EL + G + SVGQRQL CLARA
Sbjct: 1131 MRKNLDPFNEHSDEELWKALEEVQLKEAIEDLPGKMDTELAESGSNFSVGQRQLVCLARA 1190

Query: 417  MIHRSKILVIDEATANVDGVTDACIQKTIRDFFKNATIITVAHRLHTIMNSDNVMVFEKG 238
            ++ +++IL+IDEATANVD  TD  IQ+ IR+ F   T++T+AHRL+TI++SD +MV + G
Sbjct: 1191 ILKKNRILIIDEATANVDPRTDELIQQKIREKFAQCTVLTIAHRLNTIIDSDKIMVLDSG 1250

Query: 237  ELVEFDKPITLLDDQSSLFSRMAAQSG 157
             L E+D+P  LL +  SLF +M  Q G
Sbjct: 1251 RLREYDEPYVLLQNPESLFYKMVQQLG 1277


>gi|28480852|ref|XP_139262.2| similar to ATP-binding cassette
            transporter C4 [Mus musculus]
          Length = 1325

 Score =  677 bits (1748), Expect = 0.0
 Identities = 437/1347 (32%), Positives = 673/1347 (49%), Gaps = 21/1347 (1%)
 Frame = -1

Query: 4134 FYWW--------RTRNAQTDTDLLEKPSKGISAKYAAQKLESKW------ISSGPKRTHF 3997
            F+WW          R  + D      P     +K+  ++L+  W           ++
Sbjct: 23   FFWWLNPLFKTGHKRRLEEDDMFSVLPED--RSKHLGEELQRYWDKELLRAKKDSRKPSL 80

Query: 3996 LVGVWHCTKVSVMAHAISLCLEELTRVAQPLLLRELMSYYD-IEEGQEFPYWPAMQVALI 3820
               +  C   S +   I   +EE TRV QPL L +++ Y++  +         A   A +
Sbjct: 81   TKAIIKCYWKSYLILGIFTLIEEGTRVVQPLFLGKIIEYFEKYDPDDSVALHTAYGYAAV 140

Query: 3819 ISLLSFVTVCIHHPYFHGLLKVGNHARVATGVLLYRKSLRISLTSLFETNSGQIIQLLNT 3640
            +S+ + +   +HH YF+ +   G   RVA   ++YRK+LR+S +++ +T +GQI+ LL+
Sbjct: 141  LSMCTLILAILHHLYFYHVQCAGMRLRVAMCHMIYRKALRLSNSAMGKTTTGQIVNLLSN 200

Query: 3639 DAAKLEQAFLFAHYVWLCPLLMFFYAYILWSMFGFCCLLGFLVMMAIVSFQVHYSYQLGV 3460
            D  K +Q  +F H++W  PL       +LW   G  CL G  V++ ++  Q
Sbjct: 201  DVNKFDQVTIFLHFLWAGPLQAIAVTVLLWVEIGISCLAGLAVLVILLPLQSCIGKLFSS 260

Query: 3459 NRRNIGDKMDSRLKVMSEIINGIKVIKMHGWENAFAEKIRILREDEIKAVGTSAFYSSMV 3280
             R       D+R++ M+E+I G+++IKM+ WE +FA+ I  LR+ EI  +  S++   M
Sbjct: 261  LRSKTAAFTDARIRTMNEVITGMRIIKMYAWEKSFADLIANLRKKEISKILGSSYLRGMN 320

Query: 3279 MGIYFISAKIGLFVYIFACDYFDEILTTRGVFASSALFNSVXXXXXXXXXXXXXXXXXXF 3100
            M  +FI+ K+ LFV   +       +T   VF +  L+ +V
Sbjct: 321  MASFFIANKVILFVTFTSYVLLGNEITASHVFVAMTLYGAVRLTVTLFFPSAIERGSEAI 380

Query: 3099 STSRRIDLFFCLEEYSRITLELDSTDTEDGSKNEKEGLTLKKIGEKPSWTLKCDKAEKTS 2920
             + RRI  F  L+E  +    + S    DG                           K
Sbjct: 381  VSIRRIKNFLLLDELPQRKAHVPS----DG---------------------------KAI 409

Query: 2919 VFLNKVTAVWYXXXXXXXXXXXXXXXXXXDNDATVIAGEKKDEPLHVVYAVQDLSFEFVA 2740
            V +   TA W                            +  D P      +Q LSF
Sbjct: 410  VHVQDFTAFW---------------------------DKALDSP-----TLQGLSFIARP 437

Query: 2739 GTCYXXXXXXXXXXXXXXLTILSESRMTRGNLSVNGSFAYCAQEPWIFTGSIQDNIVFGS 2560
            G                   +L E     G +SV+G  AY +Q+PW+F+G+++ NI+FG
Sbjct: 438  GELLAVVGPVGAGKSSLLSAVLGELPPASGLVSVHGRIAYVSQQPWVFSGTVRSNILFGK 497

Query: 2559 EFNKERYENALELCLLTPDLRQFANGDMTIVGDNGSTLSGGQXXXXXXXXXXXXXXDIYL 2380
            ++ KERYE  ++ C L  DL+   +GD+T++GD G+TLSGGQ              DIYL
Sbjct: 498  KYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGATLSGGQKARVNLARAVYQDADIYL 557

Query: 2379 LDDPLSAVDAHVGKKLYENLIRGFLSDKLVILVTHQIHFLSELDSVILMKNNKMVGNGSL 2200
            LDDPLSAVDA VGK L++  I   L +K+ ILVTHQ+ +L     ++++K+ +MV  G+
Sbjct: 558  LDDPLSAVDAEVGKHLFQLCICQALHEKITILVTHQLQYLKAASHILILKDGEMVQKGTY 617

Query: 2199 DELKSTFTDDFIKLQAVETEVQSDELFVDGXXXXXXXXPVNIESMEKINKESIFQRANSV 2020
             E   +  D    L+    E +                  +I S +  ++ S+    +
Sbjct: 618  TEFLKSGVDFGSLLKKENEEAEPSTAPGTPTLRKRTFSEASIWSQQS-SRPSL---KDGA 673

Query: 2019 LSGSKMSETEYVKEIVYESRKSGTISWSVYWEYTRGVINPLKYGIWLVVCVLITQLMNNF 1840
              G     T+ V+    ESR  G I +  Y  Y     +   + I+LV+  ++ Q+
Sbjct: 674  PEGQDAENTQAVQP--EESRSEGRIGFKAYKNYFSAGASWF-FIIFLVLLNMVGQVFYVL 730

Query: 1839 VDWWLNKWLVDLDMNNADNSTSKEEFNRNVDVLGYTFNVTFQTYELTFIISTVIMSILGV 1660
             DWWL+ W    +   A N+T     N        T  +    Y   +   T +  + G+
Sbjct: 731  QDWWLSHW---ANKQGALNNTRNANGN-------ITETLDLSWYLGIYAGLTAVTVLFGI 780

Query: 1659 VRSVWFRNAQLMASRILHNSMFDCVLKTESEFFDKNSEGMILNRFSKDIGLTDDLLAFTY 1480
             RS+      + AS+ LHN MF+ +LK    FFD+N  G ILNRFSKDIG  DDLL  T+
Sbjct: 781  ARSLLVFYILVNASQTLHNRMFESILKAPVLFFDRNPIGRILNRFSKDIGHMDDLLPLTF 840

Query: 1479 FEFVFGTLTFVGIVGLVSMVRPIVILACAFITAGFYFCRKMYVHRSRELKRIEAAARSPL 1300
             +F+   L  V ++ + + V P +++    ++  F   R+ ++  SR++KR+E+  RSP+
Sbjct: 841  LDFIQTLLLVVSVIAVAAAVIPWILIPLVPLSVVFLVLRRYFLETSRDVKRLESTTRSPV 900

Query: 1299 NTTITSTVHGLSTIRAYRKENEMIEKFCALHDVYMAAYNMGLLSARWFGICIDXXXXXXX 1120
             + ++S++ GL TIRAY+ E    E F A  D++  A+ + L ++RWF + +D
Sbjct: 901  FSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAIFV 960

Query: 1119 XXXXXXXXLQYETLTVGEVGLCLVCAVQLSGFFSWIMRQSAELENGMVSVERVLEYTKLK 940
                    +  +TL  G+VGL L  A+ L G F W +RQSAE+EN M+SVERV+EYT L+
Sbjct: 961  IVVAFGSLVLAKTLNAGQVGLALSYALTLMGMFQWSVRQSAEVENMMISVERVIEYTDLE 1020

Query: 939  SE---EEARRPHDAYLDKQLLNSWPTKGEIEFENVSVNYG--ETKVLKNLSFVVLGGQKI 775
             E   E  +RP            WP +G I F+NV+  Y      VLK+L+ ++   +K+
Sbjct: 1021 KEAPWECKKRPPP---------GWPHEGVIVFDNVNFTYSLDGPLVLKHLTALIKSREKV 1071

Query: 774  GVVGRTGAGKSTLIKIIFGLKEYCSGRVTIDGVDLDHISLNFRRGGMSIIPQEPVIFSGT 595
            G+VGRTGAGKS+LI  +F L E   G++ ID +    I L+  R  MSIIPQEPV+F+GT
Sbjct: 1072 GIVGRTGAGKSSLISALFRLSE-PEGKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGT 1130

Query: 594  VRENLDPFDEYDDATIWFALEQCELKRSITKEKG-LNVELGQRGVSLSVGQRQLFCLARA 418
            +R+NLDPF+E+ D  +W ALE+ +LK +I    G ++ EL + G + SVGQRQL CLARA
Sbjct: 1131 MRKNLDPFNEHTDEELWRALEEVQLKEAIEDLPGKMDTELAESGSNFSVGQRQLVCLARA 1190

Query: 417  MIHRSKILVIDEATANVDGVTDACIQKTIRDFFKNATIITVAHRLHTIMNSDNVMVFEKG 238
            ++  ++IL+IDEATANVD  TD  IQ+ IR+ F   T++T+AHRL+TI++SD +MV + G
Sbjct: 1191 ILKNNRILIIDEATANVDPRTDELIQQKIREKFAQCTVLTIAHRLNTIIDSDKIMVLDSG 1250

Query: 237  ELVEFDKPITLLDDQSSLFSRMAAQSG 157
             L E+D+P  LL +  SLF +M  Q G
Sbjct: 1251 RLKEYDEPYVLLQNPESLFYKMVQQLG 1277


>gi|45862334|gb|AAS78929.1| multidrug resistance-associated protein 4
            splice variant [Rattus norvegicus]
          Length = 1288

 Score =  677 bits (1746), Expect = 0.0
 Identities = 429/1281 (33%), Positives = 657/1281 (50%), Gaps = 7/1281 (0%)
 Frame = -1

Query: 3978 CTKVSVMAHAISLCLEELTRVAQPLLLRELMSYYD-IEEGQEFPYWPAMQVALIISLLSF 3802
            C   S +   I   +EE TRV QP+ L +++ Y++  +         A   A ++SL +
Sbjct: 50   CYWKSYLILGIFTLIEETTRVVQPIFLGKIIDYFEKYDSDDSAALHTAYGYAAVLSLCTL 109

Query: 3801 VTVCIHHPYFHGLLKVGNHARVATGVLLYRKSLRISLTSLFETNSGQIIQLLNTDAAKLE 3622
            +   +HH YF+ +   G   RVA   ++YRK+LR+S +++ +T +GQI+ LL+ D  K +
Sbjct: 110  ILAILHHLYFYHVQCAGMRIRVAMCHMIYRKALRLSNSAMGKTTTGQIVNLLSNDVNKFD 169

Query: 3621 QAFLFAHYVWLCPLLMFFYAYILWSMFGFCCLLGFLVMMAIVSFQVHYSYQLGVNRRNIG 3442
            Q  +F H++W  PL       +LW   G  CL G  +++ ++  Q          R
Sbjct: 170  QVTIFLHFLWAGPLQAIGVTILLWVEIGISCLAGLAILVILLPLQSCIGKLFSSLRSKTA 229

Query: 3441 DKMDSRLKVMSEIINGIKVIKMHGWENAFAEKIRILREDEIKAVGTSAFYSSMVMGIYFI 3262
               D+R + M+E+I G+++IKM+ WE +FA+ I  LR+ EI  +  S++   M M  +FI
Sbjct: 230  AFTDARFRTMNEVITGMRIIKMYAWEKSFADLITNLRKKEISKILGSSYLRGMNMASFFI 289

Query: 3261 SAKIGLFVYIFACDYFDEILTTRGVFASSALFNSVXXXXXXXXXXXXXXXXXXFSTSRRI 3082
            + K+ LFV           +T+  VF +  L+ +V                    + RRI
Sbjct: 290  ANKVILFVTFTTYVLLGNKITSSHVFVAMTLYGAVRLTVTLFFPSAIERVSEAVVSVRRI 349

Query: 3081 DLFFCLEEYSRITLELDSTDTEDGSKNEKEGLTLKKIGEKPSWTLKCDKAEKTSVFLNKV 2902
              F  L+E      E  + +  DG                           K  V +
Sbjct: 350  KNFLLLDELP----ERKAQEPSDG---------------------------KAIVHVQDF 378

Query: 2901 TAVWYXXXXXXXXXXXXXXXXXXDNDATVIAGEKKDEPLHVVYAVQDLSFEFVAGTCYXX 2722
            TA W                            +  D P      +Q LSF    G
Sbjct: 379  TAFW---------------------------DKALDTP-----TLQGLSFTARPGELLAV 406

Query: 2721 XXXXXXXXXXXXLTILSESRMTRGNLSVNGSFAYCAQEPWIFTGSIQDNIVFGSEFNKER 2542
                          +L E   T G +SV+G  AY +Q+PW+F+G+++ NI+FG ++ KER
Sbjct: 407  VGPVGAGKSSLLSAVLGELPPTSGLVSVHGRIAYVSQQPWVFSGTVRSNILFGRKYEKER 466

Query: 2541 YENALELCLLTPDLRQFANGDMTIVGDNGSTLSGGQXXXXXXXXXXXXXXDIYLLDDPLS 2362
            YE  ++ C L  DL+   +GD+T++GD G+TLSGGQ              DIYLLDDPLS
Sbjct: 467  YEKVIKACALKKDLQLLEDGDLTVIGDRGATLSGGQKARVNLARAVYQDADIYLLDDPLS 526

Query: 2361 AVDAHVGKKLYENLIRGFLSDKLVILVTHQIHFLSELDSVILMKNNKMVGNGSLDELKST 2182
            AVDA VGK L++  I   L +K+ ILVTHQ+ +L     ++++K+ +MV  G+  E   +
Sbjct: 527  AVDAEVGKHLFQLCICQTLHEKITILVTHQLQYLKAASHILILKDGEMVQKGTYTEFLKS 586

Query: 2181 FTDDFIKLQAVETEVQSDELFVDGXXXXXXXXPVNIESMEKINKESIFQRANSVLSGSKM 2002
              D    L+    E +   +              +I S +  ++ S+    + V
Sbjct: 587  GVDFGSLLKKENEEAEPSPVPGTPTLRNRTFSEASIWSQQS-SRPSL---KDGVPDAQDA 642

Query: 2001 SETEYVKEIVYESRKSGTISWSVYWEYTRGVINPLKYGIWLVVCVLITQLMNNFVDWWLN 1822
              T+  +    ESR  G I +  Y  Y     +   + I+LV+  L+ Q+     DWWL+
Sbjct: 643  ENTQAAQP--EESRSEGRIGFKAYKNYFSAGASWF-FIIFLVLLNLMGQVFYVLQDWWLS 699

Query: 1821 KWLVDLDMNNADNSTSKEEFNRNVDVLGYTFNVTFQTYELTFIISTVIMSILGVVRSVWF 1642
             W    +   A N T     N N +V G    +    Y   +   T +  + G+ RS+
Sbjct: 700  HWA---NRQGALNDTK----NANGNVTG---TLDLSWYLGIYTGLTAVTVLFGIARSLLV 749

Query: 1641 RNAQLMASRILHNSMFDCVLKTESEFFDKNSEGMILNRFSKDIGLTDDLLAFTYFEFVFG 1462
                + AS+ LHN MF+ +LK    FFD+N  G ILNRFSKDIG  DDLL  T+ +F+
Sbjct: 750  FYVLVNASQTLHNRMFESILKAPVLFFDRNPIGRILNRFSKDIGHMDDLLPLTFLDFIQT 809

Query: 1461 TLTFVGIVGLVSMVRPIVILACAFITAGFYFCRKMYVHRSRELKRIEAAARSPLNTTITS 1282
             L  V ++ + + V P +++    ++  F   R+ ++  SR++KR+E+  RSP+ + ++S
Sbjct: 810  LLLVVSVIAVAAAVIPWILIPLVPLSIIFVVLRRYFLETSRDVKRLESTTRSPVFSHLSS 869

Query: 1281 TVHGLSTIRAYRKENEMIEKFCALHDVYMAAYNMGLLSARWFGICIDXXXXXXXXXXXXX 1102
            ++ GL TIRAY+ E    E F A  D++  A+ + L ++RWF + +D
Sbjct: 870  SLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAVFVIVVAFG 929

Query: 1101 XXLQYETLTVGEVGLCLVCAVQLSGFFSWIMRQSAELENGMVSVERVLEYTKLKSE---E 931
              +  +TL  G+VGL L  ++ L G F W +RQSAE+EN M+SVERV+EYT L+ E   E
Sbjct: 930  SLVLAKTLDAGQVGLALSYSLTLMGMFQWSVRQSAEVENMMISVERVIEYTDLEKEAPWE 989

Query: 930  EARRPHDAYLDKQLLNSWPTKGEIEFENVSVNYG--ETKVLKNLSFVVLGGQKIGVVGRT 757
              +RP            WP +G I F+NV+  Y      VLK+L+ ++   +K+G+VGRT
Sbjct: 990  CRKRPPP---------GWPHEGVIVFDNVNFTYSLDGPLVLKHLTALIKSREKVGIVGRT 1040

Query: 756  GAGKSTLIKIIFGLKEYCSGRVTIDGVDLDHISLNFRRGGMSIIPQEPVIFSGTVRENLD 577
            GAGKS+LI  +F L E   G++ ID +    I L+  R  MSIIPQEPV+F+GT+R+NLD
Sbjct: 1041 GAGKSSLISALFRLSE-PEGKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLD 1099

Query: 576  PFDEYDDATIWFALEQCELKRSITKEKG-LNVELGQRGVSLSVGQRQLFCLARAMIHRSK 400
            PF+E+ D  +W ALE+ +LK +I    G ++ EL + G + SVGQRQL CLARA++ +++
Sbjct: 1100 PFNEHSDEELWKALEEVQLKEAIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILKKNR 1159

Query: 399  ILVIDEATANVDGVTDACIQKTIRDFFKNATIITVAHRLHTIMNSDNVMVFEKGELVEFD 220
            IL+IDEATANVD  TD  IQ+ IR+ F   T++T+AHRL+TI++SD +MV + G L E+D
Sbjct: 1160 ILIIDEATANVDPRTDELIQQKIREKFAQCTVLTIAHRLNTIIDSDKIMVLDSGRLREYD 1219

Query: 219  KPITLLDDQSSLFSRMAAQSG 157
            +P  LL +  SLF +M  Q G
Sbjct: 1220 EPYVLLQNPESLFYKMVQQLG 1240


>gi|23305895|gb|AAN17334.1| ATP-binding cassette protein C4 splice
            variant A [Homo sapiens]
          Length = 1278

 Score =  658 bits (1698), Expect = 0.0
 Identities = 425/1294 (32%), Positives = 658/1294 (50%), Gaps = 9/1294 (0%)
 Frame = -1

Query: 3978 CTKVSVMAHAISLCLEELTRVAQPLLLRELMSYYDIEEGQE-FPYWPAMQVALIISLLSF 3802
            C   S +   I   +EE  +V QP+ L ++++Y++  +  +      A   A +++  +
Sbjct: 87   CYWKSYLVLGIFTLIEESAKVIQPIFLGKIINYFENYDPMDSVALNTAYAYATVLTFCTL 146

Query: 3801 VTVCIHHPYFHGLLKVGNHARVATGVLLYRKSLRISLTSLFETNSGQIIQLLNTDAAKLE 3622
            +   +HH YF+ +   G   RVA   ++YRK+LR+S  ++ +T +GQI+ LL+ D  K +
Sbjct: 147  ILAILHHLYFYHVQCAGMRLRVAMCHMIYRKALRLSNMAMGKTTTGQIVNLLSNDVNKFD 206

Query: 3621 QAFLFAHYVWLCPLLMFFYAYILWSMFGFCCLLGFLVMMAIVSFQVHYSYQLGVNRRNIG 3442
            Q  +F H++W  PL       +LW   G  CL G  V++ ++  Q  +       R
Sbjct: 207  QVTVFLHFLWAGPLQAIAVTALLWMEIGISCLAGMAVLIILLPLQSCFGKLFSSLRSKTA 266

Query: 3441 DKMDSRLKVMSEIINGIKVIKMHGWENAFAEKIRILREDEIKAVGTSAFYSSMVMGIYFI 3262
               D+R++ M+E+I GI++IKM+ WE +F+  I  LR+ EI  +  S+    M +  +F
Sbjct: 267  TFTDARIRTMNEVITGIRIIKMYAWEKSFSNLITNLRKKEISKILRSSCLRGMNLASFFS 326

Query: 3261 SAKIGLFVYIFACDYFDEILTTRGVFASSALFNSVXXXXXXXXXXXXXXXXXXFSTSRRI 3082
            ++KI +FV          ++T   VF +  L+ +V                    + RRI
Sbjct: 327  ASKIIVFVTFTTYVLLGSVITASRVFVAVTLYGAVRLTVTLFFPSAIERVSEAIVSIRRI 386

Query: 3081 DLFFCLEEYSRITLELDSTDTEDGSKNEKEGLTLKKIGEKPSWTLKCDKAEKTSVFLNKV 2902
              F  L+E S+   +L S    DG          KK+     +T   DKA +T
Sbjct: 387  QTFLLLDEISQRNRQLPS----DG----------KKMVHVQDFTAFWDKASETPT----- 427

Query: 2901 TAVWYXXXXXXXXXXXXXXXXXXDNDATVIAGEKKDEPLHVVYAVQDLSFEFVAGTCYXX 2722
                                                        +Q LSF    G
Sbjct: 428  --------------------------------------------LQGLSFTVRPGELLAV 443

Query: 2721 XXXXXXXXXXXXLTILSESRMTRGNLSVNGSFAYCAQEPWIFTGSIQDNIVFGSEFNKER 2542
                          +L E   + G +SV+G  AY +Q+PW+F+G+++ NI+FG ++ KER
Sbjct: 444  VGPVGAGKSSLLSAVLGELAPSHGLVSVHGRIAYVSQQPWVFSGTLRSNILFGKKYEKER 503

Query: 2541 YENALELCLLTPDLRQFANGDMTIVGDNGSTLSGGQXXXXXXXXXXXXXXDIYLLDDPLS 2362
            YE  ++ C L  DL+   +GD+T++GD G+TLSGGQ              DIYLLDDPLS
Sbjct: 504  YEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADIYLLDDPLS 563

Query: 2361 AVDAHVGKKLYENLIRGFLSDKLVILVTHQIHFLSELDSVILMKNNKMVGNGSLDE-LKS 2185
            AVDA V + L+E  I   L +K+ ILVTHQ+ +L     ++++K+ KMV  G+  E LKS
Sbjct: 564  AVDAEVSRHLFELCICQILHEKITILVTHQLQYLKAASQILILKDGKMVQKGTYTEFLKS 623

Query: 2184 TFTDDFIKLQAVETEVQSDELFVDGXXXXXXXXPVNIESMEKINKESIFQRANSVLSGSK 2005
                DF  L   + E +S++  V G                  ++ S++         S+
Sbjct: 624  GI--DFGSLLKKDNE-ESEQPPVPGTPTLRN---------RTFSESSVW---------SQ 662

Query: 2004 MSETEYVKEIVYESRKSGTISWSVYWEYTRGVINPLKYGIWLVVCVLITQLMNNFVDWWL 1825
             S    +K+   ES+    +                              L + ++ +W
Sbjct: 663  QSSRPSLKDGALESQDVAYV------------------------------LQDWWLSYWA 692

Query: 1824 NKW-LVDLDMNNADNSTSKEEFNRNVDVLGYTFNVTFQTYELTFIISTVIMSILGVVRSV 1648
            NK  ++++ +N   N T K + N  + +               +   TV   + G+ RS+
Sbjct: 693  NKQSMLNVTVNGGGNVTEKLDLNWYLGI---------------YSGLTVATVLFGIARSL 737

Query: 1647 WFRNAQLMASRILHNSMFDCVLKTESEFFDKNSEGMILNRFSKDIGLTDDLLAFTYFEFV 1468
                  + +S+ LHN MF+ +LK    FFD+N  G ILNRFSKDIG  DDLL  T+ +F+
Sbjct: 738  LVFYVLVNSSQTLHNKMFESILKAPVLFFDRNPIGRILNRFSKDIGHLDDLLPLTFLDFI 797

Query: 1467 FGTLTFVGIVGLVSMVRPIVILACAFITAGFYFCRKMYVHRSRELKRIEAAARSPLNTTI 1288
               L  VG+V +   V P + +    +   F F R+ ++  SR++KR+E+  RSP+ + +
Sbjct: 798  QTLLQVVGVVSVAVAVIPWIAIPLVPLGIIFIFLRRYFLETSRDVKRLESTTRSPVFSHL 857

Query: 1287 TSTVHGLSTIRAYRKENEMIEKFCALHDVYMAAYNMGLLSARWFGICIDXXXXXXXXXXX 1108
            +S++ GL TIRAY+ E    E F A  D++  A+ + L ++RWF + +D
Sbjct: 858  SSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAMFVIIVA 917

Query: 1107 XXXXLQYETLTVGEVGLCLVCAVQLSGFFSWIMRQSAELENGMVSVERVLEYTKLKSE-- 934
                +  +TL  G+VGL L  A+ L G F W +RQSAE+EN M+SVERV+EYT L+ E
Sbjct: 918  FGSLILAKTLDAGQVGLALSYALTLMGMFQWCVRQSAEVENMMISVERVIEYTDLEKEAP 977

Query: 933  -EEARRPHDAYLDKQLLNSWPTKGEIEFENVSVNY--GETKVLKNLSFVVLGGQKIGVVG 763
             E  +RP  A         WP +G I F+NV+  Y  G   VLK+L+ ++   +K+G+VG
Sbjct: 978  WEYQKRPPPA---------WPHEGVIIFDNVNFMYSPGGPLVLKHLTALIKSQEKVGIVG 1028

Query: 762  RTGAGKSTLIKIIFGLKEYCSGRVTIDGVDLDHISLNFRRGGMSIIPQEPVIFSGTVREN 583
            RTGAGKS+LI  +F L E   G++ ID +    I L+  R  MSIIPQEPV+F+GT+R+N
Sbjct: 1029 RTGAGKSSLISALFRLSE-PEGKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKN 1087

Query: 582  LDPFDEYDDATIWFALEQCELKRSITKEKG-LNVELGQRGVSLSVGQRQLFCLARAMIHR 406
            LDPF+E+ D  +W AL++ +LK +I    G ++ EL + G + SVGQRQL CLARA++ +
Sbjct: 1088 LDPFNEHTDEELWNALQEVQLKETIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILRK 1147

Query: 405  SKILVIDEATANVDGVTDACIQKTIRDFFKNATIITVAHRLHTIMNSDNVMVFEKGELVE 226
            ++IL+IDEATANVD  TD  IQK IR+ F + T++T+AHRL+TI++SD +MV + G L E
Sbjct: 1148 NQILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIAHRLNTIIDSDKIMVLDSGRLKE 1207

Query: 225  FDKPITLLDDQSSLFSRMAAQSGAENFDSLRAAA 124
            +D+P  LL ++ SLF +M  Q G     +L   A
Sbjct: 1208 YDEPYVLLQNKESLFYKMVQQLGKAEAAALTETA 1241


>gi|24648279|ref|NP_650838.1| CG4562-PA [Drosophila melanogaster]
 gi|23171755|gb|AAF55707.2| CG4562-PA [Drosophila melanogaster]
          Length = 1362

 Score =  654 bits (1686), Expect = 0.0
 Identities = 438/1383 (31%), Positives = 690/1383 (49%), Gaps = 31/1383 (2%)
 Frame = -1

Query: 4179 DSAGLISSILFSFVGFYWWRTRNAQTDTDLLEKPSKGISAKYAAQKLESKWISSGPKR-- 4006
            + + + SS++F F    +++ R    D + L +  +   + +   KL + W     K+
Sbjct: 15   EKSNIFSSLMFCFAMPTFFKGRKKTLDENDLYRALQEHRSDHLGSKLSAAWEKEVEKKRK 74

Query: 4005 ---------THFLVGVWHCTKVSVMAHAISLCLEELTRVAQPLLLRELMSYYDIEEGQEF 3853
                         V  W    + +    +   LE   RV QPL L  L++YY     QE
Sbjct: 75   KKKTPSLLKASMNVFGWRLAGLGL----VLFILEIGFRVTQPLFLGGLVAYYADASNQEG 130

Query: 3852 P-YWPAMQVALIISLLSFVTVCIHHPYFHGLLKVGNHARVATGVLLYRKSLRISLTSLFE 3676
                 A   AL + L S   V   HPY  G+  +G  AR+A   ++YRK+LR+S T+L +
Sbjct: 131  DNQTKAYLYALGVILTSACNVLFMHPYMLGMFHIGMKARIAMTSMIYRKALRLSRTALGD 190

Query: 3675 TNSGQIIQLLNTDAAKLEQAFLFAHYVWLCPLLMFFYAYILWSMFGFCCLLGFLVMMAIV 3496
            T  GQ++ L++ D  +L+ + +  +Y+WL P+ +    Y+++   G     G  VM+  +
Sbjct: 191  TTIGQVVNLISNDVGRLDVSVIHMNYLWLGPVEIGIITYLMYREIGISAFFGVAVMLLFI 250

Query: 3495 SFQVHYSYQLGVNRRNIGDKMDSRLKVMSEIINGIKVIKMHGWENAFAEKIRILREDEIK 3316
              Q +   +  V R     + D R+++M+EII+GI+VIKM+ WE  F++ I  +R  E+
Sbjct: 251  PLQAYLGKKTSVLRLKTALRTDERVRMMNEIISGIQVIKMYAWEIPFSKMINYVRTKEMN 310

Query: 3315 AVGTSAFYSSMVMGIYFISAKIGLFVYIFACDYFDEILTTRGVFASSALFNSVXXXXXXX 3136
            A+    +    +        +I +FV +       ++LT    F  +A +N +
Sbjct: 311  AIRNVNYIRGTLQSFIMFVTRISVFVSLVGFVLLGKLLTAEKAFVITAYYNILRNTMTVY 370

Query: 3135 XXXXXXXXXXXFSTSRRIDLFFCLEEYSRITLELDSTDTEDGSKNEKEGLTLKKIGEKPS 2956
                         + RRI  F   EE    T   D ++  D  K  K GL  +    + +
Sbjct: 371  FPMGISQFAELLVSIRRIQTFMLHEE----TKVRDKSEDLDEQKLGKAGLIAEPTVAQTT 426

Query: 2955 WTLKCDKAEKT----SVFLNKVTAVWYXXXXXXXXXXXXXXXXXXDNDATVIAGEKKDEP 2788
              LK      +    S+ ++K+ A W                   + D T+     K +P
Sbjct: 427  GVLKPSSRRTSEAEHSIVISKLKAKW----------------DQKNTDNTLDNISLKFKP 470

Query: 2787 LHVVYAVQDLSFEFVAGTCYXXXXXXXXXXXXXXLTILSESRMTRGNLSVNGSFAYCAQE 2608
              +V  +  +                          +L E     G++ VNG+ +Y +QE
Sbjct: 471  RQLVAVIGPVG----------------SGKSSLIQAVLGELNPDSGSVKVNGTLSYASQE 514

Query: 2607 PWIFTGSIQDNIVFGSEFNKERYENALELCLLTPDLRQFANGDMTIVGDNGSTLSGGQXX 2428
            PW+FTG+++ NI+FG   +K RY   ++ C L  D       D TIVG+ G++LSGGQ
Sbjct: 515  PWLFTGTVRQNILFGLPMDKHRYRTVVKRCALERDFELLPYADKTIVGERGASLSGGQKA 574

Query: 2427 XXXXXXXXXXXXDIYLLDDPLSAVDAHVGKKLYENLIRGFLSDKLVILVTHQIHFLSELD 2248
                        DIYLLDDPLSAVD HVG+ L++  +RGFL +++V+LVTHQ+ FL + D
Sbjct: 575  RISLARAVYRKADIYLLDDPLSAVDTHVGRHLFDQCMRGFLREEIVLLVTHQLQFLEQAD 634

Query: 2247 SVILMKNNKMVGNGSLDELKSTFTDDFIKLQAVETEVQSDELFVDGXXXXXXXXPVNIES 2068
             +++M   K+   G+ + +  +  D     Q +    + DE   D           N +
Sbjct: 635  VIVIMDKGKISAMGTYESMAKSGLD---FAQMLTDPSKKDEGAGDAPDKKSLSRQ-NSKL 690

Query: 2067 MEKINKESIFQRANSVLSGSKMSETEYVKEIVYESRKSGTISWSVYWEYTRGVINPLKYG 1888
             ++    S  + A   L+     +T+       E R  G I   +Y +Y         YG
Sbjct: 691  RDRHGSISSMESAAESLAAESPMQTQ-------EGRVEGRIGMKLYKKY----FGANGYG 739

Query: 1887 IWLV---VCVLITQLMNN---FVDWWLNK---WLVDLDMNNADNSTSKEEFNRNVDVLGY 1735
            +++V    C+    L +    F+ +W+NK      D  M     +  +   N + D +
Sbjct: 740  LFIVFAFFCIGAQVLASGGDIFLSYWVNKNGEAERDTFMARLRRAFPETRINADTDPV-- 797

Query: 1734 TFNVTFQTYELTFIISTVIMSILGVVRSVWFRNAQLMASRILHNSMFDCVLKTESEFFDK 1555
                    Y  T I  +VI  I  +VRS+ F    + +S  LHN+MF  V +    FF+
Sbjct: 798  ------DIYYFTGINVSVI--IFSLVRSMLFFYLAMRSSTTLHNTMFQGVTRAAMHFFNT 849

Query: 1554 NSEGMILNRFSKDIGLTDDLLAFTYFEFVFGTLTFVGIVGLVSMVRPIVILACAFITAGF 1375
            N  G ILNRFSKD+G  D++L     + +   L  VGIV ++ ++    ILA  F+   F
Sbjct: 850  NPSGRILNRFSKDLGQVDEILPSVMMDVMQIFLAIVGIVVVLCIINVWYILATVFLVIVF 909

Query: 1374 YFCRKMYVHRSRELKRIEAAARSPLNTTITSTVHGLSTIRAYRKENEMIEKFCALHDVYM 1195
            Y  R  Y+  SR++KR+EA  RSP+ + ++++++GL+TIRA+  + E+I +F    D++
Sbjct: 910  YLLRVFYLSTSRDVKRLEAVTRSPIYSHLSASLNGLATIRAFGAQKELIAEFDNYQDMHS 969

Query: 1194 AAYNMGLLSARWFGICIDXXXXXXXXXXXXXXXLQYETLTVGEVGLCLVCAVQLSGFFSW 1015
            + Y M L ++R FG  +D               L +     G+VGL +  A+ ++G   W
Sbjct: 970  SGYYMFLATSRAFGYWLDCVCVVYIAVITLSFFL-FSPENGGDVGLAITQAMGMTGMVQW 1028

Query: 1014 IMRQSAELENGMVSVERVLEYTKLKSEEEARRPHDAYLDKQLLNSWPTKGEIEFENVSVN 835
             MRQSAELEN M +VERV+EY  L+ E +     ++  +K+    WP  G+I F+++S+
Sbjct: 1029 GMRQSAELENTMTAVERVVEYEDLEPEGD----FESKPNKKPPKDWPEDGKIVFDDLSLK 1084

Query: 834  YGETK----VLKNLSFVVLGGQKIGVVGRTGAGKSTLIKIIFGLKEYCSGRVTIDGVDLD 667
            Y   K    VL++L+  + G +K+G+VGRTGAGKS+LI  +F L  Y  G + ID  D +
Sbjct: 1085 YFPDKAADYVLRSLNIAIEGCEKVGIVGRTGAGKSSLINALFRL-SYNEGAILIDRRDTN 1143

Query: 666  HISLNFRRGGMSIIPQEPVIFSGTVRENLDPFDEYDDATIWFALEQCELKRSITK-EKGL 490
             + L+  R  +SIIPQEPV+FSGT+R NLDPFDEY DA +W +LE+ +LK+ +     GL
Sbjct: 1144 DLGLHDLRSKISIIPQEPVLFSGTMRYNLDPFDEYSDAKLWESLEEVKLKQVVADLPSGL 1203

Query: 489  NVELGQRGVSLSVGQRQLFCLARAMIHRSKILVIDEATANVDGVTDACIQKTIRDFFKNA 310
              ++ + G + SVGQRQL CLARA++  ++ILV+DEATANVD  TDA IQ TIR+ FK+
Sbjct: 1204 QSKISEGGTNFSVGQRQLVCLARAILRENRILVMDEATANVDPQTDALIQTTIRNKFKDC 1263

Query: 309  TIITVAHRLHTIMNSDNVMVFEKGELVEFDKPITLL-DDQSSLFSRMAAQSGAENFDSLR 133
            T++T+AHRLHT+M+SD V+V + G+ VEF  P  LL   +  +F  M  Q+G   FD+L
Sbjct: 1264 TVLTIAHRLHTVMDSDKVLVMDAGKAVEFGSPFELLTTSEKKVFHSMVKQTGDSTFDALL 1323

Query: 132  AAA 124
              A
Sbjct: 1324 KVA 1326


>gi|24582795|ref|NP_609215.2| CG7627-PA [Drosophila melanogaster]
 gi|7297388|gb|AAF52648.1| CG7627-PA [Drosophila melanogaster]
          Length = 1327

 Score =  647 bits (1669), Expect = 0.0
 Identities = 424/1347 (31%), Positives = 675/1347 (49%), Gaps = 28/1347 (2%)
 Frame = -1

Query: 4092 LLEKPSKGISAKYAAQ-KLESKWISSGPKRTHFLVGV--WHCTKVSVMAHAISLCLEELT 3922
            L E  S+ +  K  A  +LE +     P     L+ V  W+   + ++   + L L
Sbjct: 21   LKEHKSETLGNKLCASWELELEKTKGKPNLLRALLRVFGWYFALLGLVLFLLELGL---- 76

Query: 3921 RVAQPLLLRELMSYYDI-EEGQEFPYWPAMQVALIISLLSFVTVCIHHPYFHGLLKVGNH 3745
            R  QP+ L +L++YY    E  E  Y+ A  V L  +L     V I HPY  G + VG
Sbjct: 77   RTLQPIFLLKLIAYYTHGSESIESAYYYAAGVILCSAL----NVIIMHPYMLGTMHVGLK 132

Query: 3744 ARVATGVLLYRKSLRISLTSLFETNSGQIIQLLNTDAAKLEQAFLFAHYVWLCPLLMFFY 3565
             RV    ++YRK+LR+S ++L +T +G ++ L++ D  +L+ A +F HY+W+ PL   F
Sbjct: 133  MRVGMCSMIYRKALRLSKSALGDTTAGHVVNLMSNDVGRLDLATIFVHYLWVGPLETLFI 192

Query: 3564 AYILWSMFGFCCLLGFLVMMAIVSFQVHYSYQLGVNRRNIGDKMDSRLKVMSEIINGIKV 3385
             Y+++   G   + G   M+  +  Q +   +  V R     + D R+++M+EII+GI+V
Sbjct: 193  TYLMYREIGIAAVFGVAFMLLFIPLQAYLGKRTSVLRLRTALRTDERVRMMNEIISGIQV 252

Query: 3384 IKMHGWENAFAEKIRILREDEIKAVGTSAFYSSMVMGIYFISAKIGLFVYIFACDYFDEI 3205
            IKM+ WE  F   +   R+ EI A+   ++   +++       ++ +F+ +
Sbjct: 253  IKMYAWELPFEHMVAFARKKEINAIRHVSYIRGILLSFIIFLTRVSIFLSLVGYVLLGTF 312

Query: 3204 LTTRGVFASSALFNSVXXXXXXXXXXXXXXXXXXFSTSRRIDLFFCLEEYSRITLELDST 3025
            LT    F  +A +N +                    + +R+  +   +E + + + +D T
Sbjct: 313  LTPEVAFLITAYYNILRTTMTVFFPQGISQMAETLVSIKRVQKYMQSDETNVMDMSVDLT 372

Query: 3024 DTEDGSKNE---------KEGLTLKKIGEKPSWTLKCDKAEKTSVFLNKVTAVWYXXXXX 2872
            +   GS  E         ++    K +G   +   +  K  +  + ++ + A W
Sbjct: 373  EDFQGSNQETVHADGDEERDEAEDKLLGPPIATVNENAKLSEAGISISGLMAKWDVNSPD 432

Query: 2871 XXXXXXXXXXXXXDNDATVIAGEKKDEPLHVVYAVQDLSFEFVAGTCYXXXXXXXXXXXX 2692
                                            Y++  ++     GT
Sbjct: 433  --------------------------------YSLNGVNLRVQPGTMLGIVGRTGSGKSS 460

Query: 2691 XXLTILSESRMTRGNLSVNGSFAYCAQEPWIFTGSIQDNIVFGSEFNKERYENALELCLL 2512
                IL E     G + VNGS +Y +QEPW+F+G+++ NI+FG   ++ RY   ++ C L
Sbjct: 461  LIQAILGELPAESGEIKVNGSMSYASQEPWLFSGTVRQNILFGQPMDRRRYAKVVKKCAL 520

Query: 2511 TPDLRQFANGDMTIVGDNGSTLSGGQXXXXXXXXXXXXXXDIYLLDDPLSAVDAHVGKKL 2332
              D       D TIVG+ G++LSGGQ               IYLLDDPLSAVD HV + L
Sbjct: 521  ERDFELLPFKDKTIVGERGASLSGGQKARISLARAVYRETSIYLLDDPLSAVDTHVARHL 580

Query: 2331 YENLIRGFLSDKLVILVTHQIHFLSELDSVILMKNNKMVGNGSLDELKSTFTDDFIKLQA 2152
            +E  +RG+L +++VIL THQ+ FL   D +++M   ++   G+ + L+ +  D    L
Sbjct: 581  FEQCMRGYLRERIVILATHQLQFLQHADQIVIMDKGRVSAVGTYESLRESGLDFASMLAD 640

Query: 2151 VETEVQSDELFVDGXXXXXXXXPVNIESMEKINKE-SIFQRANSVLSGSKMSETEYVKEI 1975
             E + QS+E               +  S ++ N E S+   A+S      M + E  +
Sbjct: 641  PERDEQSEE-----RSRSRSGSYTHSHSDQRRNSEQSLLSMADSC-----MDDLEAEQAN 690

Query: 1974 VYESRKSGTISWSVYWEYTRGVINPLKYGIWLVVCVL---ITQLMNNFVDWWL-NKWLVD 1807
              E +++G I   +Y +Y +       + + +  CVL   +  L + F+ +W+  K  V
Sbjct: 691  NQERQEAGQIGLRLYSKYFKAGGGFFAFFVMMGFCVLSQGLASLGDYFLSYWVTKKGNVA 750

Query: 1806 LDMNNADNSTSKE---EFNRNVDVLGYTFNV-TFQTYELTFIISTVIMSILGVVRSVWFR 1639
               +N D + S+E     +  +  +G + +     TY   F + TV+  ++ V RS  F
Sbjct: 751  YRADNNDTTRSEELEPRLSTWLRDIGLSVDAEMLDTY--IFTVITVLTILVTVARSFLFF 808

Query: 1638 NAQLMASRILHNSMFDCVLKTESEFFDKNSEGMILNRFSKDIGLTDDLLAFTYFEFVFGT 1459
            N  + AS  LHNSMF  + +    FF+ N  G ILNRFSKD+G  D++L     + +
Sbjct: 809  NLAMKASIRLHNSMFRGITRAAMYFFNTNPSGRILNRFSKDMGQVDEILPAVMMDVIQIF 868

Query: 1458 LTFVGIVGLVSMVRPIVILACAFITAGFYFCRKMYVHRSRELKRIEAAARSPLNTTITST 1279
            L   GIV ++++V P+ ++    +   FY  R  Y+  SR++KR+EA  RSP+ + + ++
Sbjct: 869  LALAGIVIVIAVVNPLFLIPTVVLGIIFYQLRTFYLKTSRDVKRMEAITRSPVYSHLAAS 928

Query: 1278 VHGLSTIRAYRKENEMIEKFCALHDVYMAAYNMGLLSARWFGICIDXXXXXXXXXXXXXX 1099
            + GLSTIRA+  +  +  +F    D++ +A+ M + ++R FG  +D
Sbjct: 929  LTGLSTIRAFGAQRVLEAEFDNYQDMHSSAFYMFISTSRAFGYWLDCFCVIYIAIITLSF 988

Query: 1098 XLQYETLTVGEVGLCLVCAVQLSGFFSWIMRQSAELENGMVSVERVLEYTKLKSEEEARR 919
             + +     G+VGL +  A+ ++G   W MRQSAELEN M +VERV+EY  ++ E
Sbjct: 989  FI-FPPANGGDVGLAITQAMGMTGMVQWGMRQSAELENTMTAVERVVEYEDIEPEGALEA 1047

Query: 918  PHDAYLDKQLLNSWPTKGEIEFENVSVNY----GETKVLKNLSFVVLGGQKIGVVGRTGA 751
            P     DK+   SWP +G+I F+ +S+ Y        VLK+LSFV+   +K+G+VGRTGA
Sbjct: 1048 P----ADKKPPKSWPEQGKIVFDELSLRYTPDPKSENVLKSLSFVIKPKEKVGIVGRTGA 1103

Query: 750  GKSTLIKIIFGLKEYCSGRVTIDGVDLDHISLNFRRGGMSIIPQEPVIFSGTVRENLDPF 571
            GKS+LI  +F L  Y  G V ID  D   + L+  R  +SIIPQEPV+FSGT+R NLDPF
Sbjct: 1104 GKSSLINALFRL-SYNDGSVLIDKRDTSEMGLHDLRSKISIIPQEPVLFSGTMRYNLDPF 1162

Query: 570  DEYDDATIWFALEQCELKRSITK-EKGLNVELGQRGVSLSVGQRQLFCLARAMIHRSKIL 394
            DEY D  +W +LE+ +LK  +     GL  ++ + G + SVGQRQL CLARA++  ++IL
Sbjct: 1163 DEYSDDKLWRSLEEVKLKEVVADLPSGLQSKITEGGTNFSVGQRQLVCLARAILRENRIL 1222

Query: 393  VIDEATANVDGVTDACIQKTIRDFFKNATIITVAHRLHTIMNSDNVMVFEKGELVEFDKP 214
            V+DEATANVD  TD  IQ TIR+ FK  T++T+AHRLHTIM+SD V+V + G  VEF  P
Sbjct: 1223 VMDEATANVDPQTDGLIQTTIRNKFKECTVLTIAHRLHTIMDSDKVLVMDAGRAVEFGTP 1282

Query: 213  ITLLD-DQSSLFSRMAAQSGAENFDSL 136
              LL    S +F  M  Q+G   ++SL
Sbjct: 1283 YELLTLADSKVFHGMVKQTGHATYESL 1309




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