Homology by BLASTX
BLASTX 2.2.4 [Aug-26-2002]
Query= F29D11_2
(14,262 letters)
Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
1,967,186 sequences; 661,712,633 total letters
Score E
Sequences producing significant alignments: (bits) Value
gi|17508271|ref|NP_492127.1| EGF motif related, Low-density lipo... 9651 0.0
gi|39582476|emb|CAE66567.1| Hypothetical protein CBG11882 [Caeno... 9213 0.0
gi|31203671|ref|XP_310784.1| ENSANGP00000014849 [Anopheles gambi... 2868 0.0
gi|24640820|ref|NP_572563.2| CG12139-PB [Drosophila melanogaster... 2841 0.0
gi|50750481|ref|XP_422014.1| PREDICTED: similar to glycoprotein ... 2672 0.0
gi|13562118|ref|NP_110454.1| low density lipoprotein receptor-re... 2602 0.0
gi|6806919|ref|NP_004516.1| low density lipoprotein-related prot... 2533 0.0
gi|32816597|gb|AAP88586.1| glycoprotein receptor gp330/megalin p... 2533 0.0
gi|32816595|gb|AAP88585.1| glycoprotein receptor gp330/megalin p... 2532 0.0
gi|47210425|emb|CAF92450.1| unnamed protein product [Tetraodon n... 2372 0.0
gi|45382557|ref|NP_990573.1| low density lipoprotein-related pro... 2076 0.0
gi|4758686|ref|NP_002323.1| low density lipoprotein-related prot... 2030 0.0
gi|15825005|gb|AAL09566.1| lipoprotein receptor-related protein ... 2029 0.0
gi|15825096|gb|AAL09567.1| lipoprotein receptor-related protein ... 2029 0.0
gi|47219712|emb|CAG12634.1| unnamed protein product [Tetraodon n... 2006 0.0
gi|6678720|ref|NP_032538.1| low density lipoprotein receptor-rel... 1998 0.0
gi|34865759|ref|XP_243524.2| similar to lipoprotein receptor-rel... 1992 0.0
gi|9055270|ref|NP_061027.1| low density lipoprotein-related prot... 1881 0.0
gi|16519539|ref|NP_443737.1| low density lipoprotein-related pro... 1877 0.0
gi|38074796|ref|XP_130308.2| similar to low density lipoprotein ... 1851 0.0
gi|34854634|ref|XP_346657.1| hypothetical protein XP_346656 [Rat... 1568 0.0
gi|48137733|ref|XP_393369.1| similar to ENSANGP00000014849 [Apis... 1527 0.0
gi|50750792|ref|XP_422146.1| PREDICTED: similar to Low-density l... 1525 0.0
gi|28573304|ref|NP_788284.1| CG33087-PC [Drosophila melanogaster... 1446 0.0
gi|16768036|gb|AAL28237.1| GH12891p [Drosophila melanogaster] 1330 0.0
gi|47228669|emb|CAG07401.1| unnamed protein product [Tetraodon n... 1119 0.0
gi|39586294|emb|CAE66705.1| Hypothetical protein CBG12050 [Caeno... 1109 0.0
gi|1389559|gb|AAB02882.1| glycoprotein 330 1096 0.0
gi|31239543|ref|XP_320185.1| ENSANGP00000011153 [Anopheles gambi... 1031 0.0
gi|47229537|emb|CAG06733.1| unnamed protein product [Tetraodon n... 971 0.0
gi|1083645|pir||S53457 dominant autoantigen gp 330 - rat (fragme... 914 0.0
gi|34853954|ref|XP_231214.2| similar to low density lipoprotein ... 876 0.0
gi|47228667|emb|CAG07399.1| unnamed protein product [Tetraodon n... 874 0.0
gi|17298317|gb|AAL38109.1| candidate tumor suppressor protein [H... 820 0.0
gi|47229539|emb|CAG06735.1| unnamed protein product [Tetraodon n... 790 0.0
gi|38074798|ref|XP_130363.2| low density lipoprotein receptor-re... 756 0.0
gi|3170549|gb|AAC34396.1| LRP1 [Takifugu rubripes] 751 0.0
gi|17298316|gb|AAL38108.1| candidate tumor suppressor protein [H... 731 0.0
gi|50748119|ref|XP_421114.1| PREDICTED: similar to Low-density l... 708 0.0
gi|47117042|sp|O75096|LRP4_HUMAN Low-density lipoprotein recepto... 692 0.0
gi|47271362|ref|NP_112612.1| low density lipoprotein receptor-re... 687 0.0
gi|47116978|sp|Q9QYP1|LRP4_RAT Low-density lipoprotein receptor-... 686 0.0
gi|47117264|sp|Q8VI56|LRP4_MOUSE Low-density lipoprotein recepto... 681 0.0
gi|27883856|ref|NP_766256.2| low density lipoprotein receptor-re... 676 0.0
gi|37541633|ref|XP_035037.3| low density lipoprotein receptor-re... 667 0.0
gi|34856544|ref|XP_342465.1| low density lipoprotein receptor-re... 646 0.0
gi|41016740|dbj|BAC02725.2| vitellogenin receptor [Periplaneta a... 625 e-177
gi|47230767|emb|CAF99960.1| unnamed protein product [Tetraodon n... 623 e-176
gi|31204353|ref|XP_311125.1| ENSANGP00000017336 [Anopheles gambi... 619 e-175
gi|34853956|ref|XP_231215.2| similar to low density lipoprotein ... 614 e-173
gi|24642347|ref|NP_727914.1| CG8909-PB [Drosophila melanogaster]... 578 e-162
gi|7511796|pir||T18308 probable vitellogenin receptor - yellow f... 566 e-159
gi|42521628|gb|AAP92450.1| vitellogenin receptor [Solenopsis inv... 559 e-157
gi|3449306|dbj|BAA32468.1| MEGF7 [Homo sapiens] 549 e-154
gi|17507419|ref|NP_491271.1| lipoprotein receptor-related protei... 545 e-152
gi|4505017|ref|NP_002327.1| low density lipoprotein receptor-rel... 535 e-149
gi|22854904|gb|AAN09807.1| lipoprotein receptor-related protein ... 533 e-149
gi|6678718|ref|NP_032540.1| low density lipoprotein receptor-rel... 533 e-149
gi|31203447|ref|XP_310672.1| ENSANGP00000020798 [Anopheles gambi... 532 e-149
gi|38174481|gb|AAH60704.1| Low density lipoprotein receptor-rela... 531 e-148
gi|28316919|gb|AAO39481.1| RE59172p [Drosophila melanogaster] 526 e-147
gi|45555120|ref|NP_996433.1| CG1372-PB [Drosophila melanogaster]... 525 e-146
gi|24641935|ref|NP_511151.2| CG1372-PA [Drosophila melanogaster]... 525 e-146
gi|7512012|pir||T13171 probable vitellogenin receptor - fruit fl... 525 e-146
gi|7508146|pir||T29764 hypothetical protein T21E3.3 - Caenorhabd... 517 e-144
gi|17509113|ref|NP_491270.1| lipoprotein receptor-related protei... 517 e-144
gi|22854902|gb|AAN09806.1| lipoprotein receptor-related protein ... 515 e-143
gi|47117043|sp|O75197|LRP5_HUMAN Low-density lipoprotein recepto... 499 e-139
gi|14028618|gb|AAK52433.1| low density lipoprotein receptor-rela... 499 e-138
gi|3831748|gb|AAC72791.1| LDL receptor member LR3 [Homo sapiens] 499 e-138
gi|4505019|ref|NP_002326.1| low density lipoprotein receptor-rel... 499 e-138
gi|34861345|ref|XP_215187.2| similar to low density lipoprotein ... 498 e-138
gi|3831750|gb|AAC70183.1| LDL receptor member LR3 [Mus musculus] 496 e-138
gi|6678716|ref|NP_032539.1| low density lipoprotein receptor-rel... 495 e-137
gi|15030228|gb|AAH11374.1| Low density lipoprotein receptor-rela... 495 e-137
gi|47209732|emb|CAF90682.1| unnamed protein product [Tetraodon n... 489 e-135
gi|49823250|gb|AAT68691.1| megalin [Didelphis virginiana] 486 e-135
gi|2764400|emb|CAA03855.1| lipophorin receptor [Locusta migratoria] 459 e-126
gi|47117276|sp|Q924X6|LRP8_MOUSE Low-density lipoprotein recepto... 453 e-125
gi|16716347|ref|NP_444303.1| low density lipoprotein receptor-re... 453 e-125
gi|28572059|ref|NP_733118.2| CG31092-PA [Drosophila melanogaster... 453 e-125
gi|7438663|pir||JE0237 apolipoprotein E receptor 2 precursor - m... 449 e-124
gi|31198095|ref|XP_307995.1| ENSANGP00000006309 [Anopheles gambi... 448 e-123
gi|6981706|ref|NP_037287.1| very low density lipoprotein recepto... 441 e-121
gi|1730112|sp|P98156|LDVR_MOUSE Very low-density lipoprotein rec... 440 e-121
gi|47213812|emb|CAF92585.1| unnamed protein product [Tetraodon n... 440 e-121
gi|34878705|ref|XP_237984.2| similar to low density lipoprotein ... 439 e-121
gi|15489005|gb|AAH13622.1| Vldlr protein [Mus musculus] 439 e-121
gi|33589552|gb|AAQ22543.1| LD11117p [Drosophila melanogaster] 439 e-120
gi|547843|sp|P35953|LDVR_RABIT Very low-density lipoprotein rece... 439 e-120
gi|1730111|sp|P98155|LDVR_HUMAN Very low-density lipoprotein rec... 438 e-120
gi|437387|gb|AAA61344.1| very low density lipoprotein receptor 438 e-120
gi|15418693|gb|AAF91072.1| arrow [Drosophila melanogaster] 437 e-120
gi|40254473|ref|NP_003374.2| very low density lipoprotein recept... 437 e-120
gi|45553532|ref|NP_996296.1| CG31094-PB [Drosophila melanogaster... 437 e-120
gi|391736|dbj|BAA03946.1| very low density lipoprotein receptor ... 437 e-120
gi|39840998|gb|AAR31134.1| LD21010p [Drosophila melanogaster] 436 e-120
gi|24653390|ref|NP_524737.2| CG5912-PA [Drosophila melanogaster]... 436 e-120
gi|24763|emb|CAA38905.1| alpha-2 macroglobulin receptor [Homo sa... 435 e-119
gi|6760453|gb|AAF28358.1| LDL-related protein LRP6 [Drosophila m... 434 e-119
gi|40231967|gb|AAR83314.1| very low density lipoprotein receptor... 434 e-119
gi|14718545|gb|AAK72954.1| lipophorin receptor [Aedes aegypti] 433 e-119
gi|476532|pir||QRXLL2 LDL receptor 2 precursor - African clawed ... 429 e-117
gi|39840984|gb|AAR31128.1| RE40649p [Drosophila melanogaster] 426 e-117
gi|476531|pir||QRXLL1 LDL receptor 1 precursor - African clawed ... 426 e-117
gi|547838|sp|Q99087|LDL1_XENLA Low-density lipoprotein receptor ... 426 e-116
gi|27806193|ref|NP_776914.1| very low density lipoprotein recept... 424 e-116
gi|3153895|gb|AAC17444.1| low density lipoprotein receptor [Sus ... 423 e-116
gi|45383976|ref|NP_990517.1| LR8B protein [Gallus gallus] >gnl|B... 422 e-116
gi|7305629|ref|NP_038731.1| very low density lipoprotein recepto... 422 e-115
gi|609533|gb|AAC37668.1| very low density lipoprotein receptor 422 e-115
gi|16610195|emb|CAD10640.1| vitellogenin receptor [Oncorhynchus ... 422 e-115
gi|3201962|gb|AAC39254.1| low density lipoprotein receptor [Sus ... 421 e-115
gi|547839|sp|Q99088|LDL2_XENLA Low-density lipoprotein receptor ... 421 e-115
gi|45382563|ref|NP_990560.1| very low density lipoprotein (VLDL)... 419 e-115
gi|28373937|pdb|1N7D|A Chain A, Extracellular Domain Of The Ldl ... 417 e-114
gi|6691161|gb|AAF24515.1| low density lipoprotein receptor [Homo... 417 e-114
gi|4504975|ref|NP_000518.1| low density lipoprotein receptor pre... 417 e-114
gi|32880123|gb|AAP88892.1| low density lipoprotein receptor (fam... 417 e-114
gi|126074|sp|P20063|LDLR_RABIT Low-density lipoprotein receptor ... 414 e-113
gi|28461161|ref|NP_786938.1| Low density lipoprotein receptor; L... 414 e-113
gi|476530|pir||QRRTLD LDL receptor precursor - rat 414 e-113
gi|17512511|gb|AAH19207.1| Ldlr protein [Mus musculus] 411 e-112
gi|7428600|pir||QRMSLD LDL receptor precursor - mouse >gnl|BL_OR... 411 e-112
gi|24650134|ref|NP_733119.1| CG31094-PA [Drosophila melanogaster... 411 e-112
gi|6754526|ref|NP_034830.1| low density lipoprotein receptor [Mu... 410 e-112
gi|4235639|gb|AAD13300.1| low density lipoprotein receptor [Sus ... 409 e-112
gi|16506799|gb|AAL23955.1| low density lipoprotein receptor [Mus... 409 e-111
gi|547840|sp|P35950|LDLR_CRIGR Low-density lipoprotein receptor ... 405 e-110
gi|37728099|gb|AAO92396.1| vitellogenin receptor [Morone americana] 403 e-110
gi|16549252|dbj|BAB70786.1| unnamed protein product [Homo sapiens] 402 e-109
gi|47227965|emb|CAF97594.1| unnamed protein product [Tetraodon n... 402 e-109
gi|28572061|ref|NP_788742.1| CG31092-PB [Drosophila melanogaster... 400 e-109
gi|33589593|gb|AAQ22563.1| GH26833p [Drosophila melanogaster] 400 e-109
gi|40231914|gb|AAR83313.1| low density lipoprotein receptor [Mac... 400 e-109
gi|1817731|gb|AAB42184.1| low-density lipoprotein receptor [Chil... 399 e-109
gi|33356181|gb|AAQ16410.1| lipophorin receptor [Aedes aegypti] 397 e-108
gi|27923331|gb|AAO27569.1| vitellogenin receptor [Oreochromis au... 395 e-107
gi|2118675|pir||JC4858 VLDL receptor precursor - African clawed ... 392 e-106
gi|30385210|gb|AAP22970.1| low density lipoprotein receptor [Dan... 392 e-106
gi|47123899|gb|AAH70552.1| VLDLR protein [Xenopus laevis] 392 e-106
gi|31240653|ref|XP_320740.1| ENSANGP00000020132 [Anopheles gambi... 388 e-105
gi|25012574|gb|AAN71387.1| RE38584p [Drosophila melanogaster] 387 e-105
gi|6681362|dbj|BAA88688.1| MEGF7 [Rattus norvegicus] 387 e-105
gi|30354634|gb|AAH51836.1| LRP8 protein [Homo sapiens] 380 e-103
gi|4758688|ref|NP_004622.1| low density lipoprotein receptor-rel... 377 e-102
gi|37360112|dbj|BAC98034.1| mKIAA0816 protein [Mus musculus] 369 1e-99
gi|14018364|emb|CAC38356.1| ApoE receptor-2 [Mus musculus] 367 3e-99
gi|21750962|dbj|BAC03874.1| unnamed protein product [Homo sapiens] 365 2e-98
gi|31198105|ref|XP_308000.1| ENSANGP00000013335 [Anopheles gambi... 360 6e-97
gi|92331|pir||A30363 glycoprotein GP330, renal - rat (fragments) 359 1e-96
gi|15451866|ref|NP_059992.2| low density lipoprotein receptor-re... 358 2e-96
gi|47217043|emb|CAG10095.1| unnamed protein product [Tetraodon n... 351 3e-94
gi|1834534|emb|CAA99509.1| apolipoprotein E receptor 2 906 [Homo... 346 1e-92
gi|47206272|emb|CAF92386.1| unnamed protein product [Tetraodon n... 336 1e-89
gi|34870155|ref|XP_342878.1| similar to ApoE receptor-2 [Rattus ... 331 3e-88
gi|45383257|ref|NP_989783.1| LDL receptor [Gallus gallus] >gnl|B... 326 9e-87
gi|15451868|ref|NP_150643.1| low density lipoprotein receptor-re... 325 2e-86
gi|50766215|ref|XP_426898.1| PREDICTED: similar to alpha-2-macro... 320 5e-85
gi|47214294|emb|CAG00960.1| unnamed protein product [Tetraodon n... 320 8e-85
gi|31201695|ref|XP_309795.1| ENSANGP00000012534 [Anopheles gambi... 318 3e-84
gi|46195864|gb|AAS80339.1| Hypothetical protein T13C2.6b [Caenor... 311 2e-82
gi|39590231|emb|CAE65969.1| Hypothetical protein CBG11153 [Caeno... 310 5e-82
gi|46195863|gb|AAS80338.1| Hypothetical protein T13C2.6a [Caenor... 309 1e-81
gi|38089188|ref|XP_146277.4| similar to low density lipoprotein ... 308 2e-81
gi|39581312|emb|CAE72333.1| Hypothetical protein CBG19478 [Caeno... 305 2e-80
gi|8928392|sp|Q95209|SORL_RABIT Sortilin-related receptor precur... 303 1e-79
gi|47211616|emb|CAF92929.1| unnamed protein product [Tetraodon n... 301 4e-79
gi|4507157|ref|NP_003096.1| sortilin-related receptor containing... 301 4e-79
gi|17506619|ref|NP_492474.1| low density lipoprotein-related pro... 298 2e-78
gi|17298315|gb|AAL38107.1| candidate tumor suppressor protein [H... 297 6e-78
gi|8928354|sp|Q98930|SORL_CHICK Sortilin-related receptor (Sorti... 293 1e-76
gi|2654025|gb|AAC16739.1| gp250 precursor [Mus musculus] 290 7e-76
gi|48096771|ref|XP_392519.1| similar to ENSANGP00000012534 [Apis... 288 2e-75
gi|8928391|sp|O88307|SORL_MOUSE Sortilin-related receptor precur... 287 5e-75
gi|45597451|ref|NP_035566.1| sortilin-related receptor, LDLR cla... 285 2e-74
gi|3021534|emb|CAA05873.1| vitellogenin receptor [Oncorhynchus m... 280 7e-73
gi|3021536|emb|CAA05874.1| somatic lipoprotein receptor [Oncorhy... 280 7e-73
gi|38089794|ref|XP_287900.2| similar to Sortilin-related recepto... 279 1e-72
gi|2135570|pir||I38467 low density lipoprotein-related protein 2... 278 3e-72
gi|26328189|dbj|BAC27835.1| unnamed protein product [Mus musculus] 278 3e-72
gi|50731507|ref|XP_417286.1| PREDICTED: similar to low density l... 278 3e-72
gi|5457146|gb|AAD43811.1| head-activator binding protein precurs... 276 8e-72
gi|34858529|ref|XP_232466.2| similar to low density lipoprotein ... 276 1e-71
gi|32565014|ref|NP_872023.1| low density lipoprotein-receptor, c... 264 5e-68
gi|15425719|dbj|BAB64337.1| vitellogenin receptor [Anguilla japo... 262 2e-67
gi|18957994|gb|AAL79675.1| putative ovarian lipoprotein receptor... 262 2e-67
gi|17536249|ref|NP_495387.1| low density lipoprotein-receptor, c... 261 3e-67
gi|47222148|emb|CAG11574.1| unnamed protein product [Tetraodon n... 259 1e-66
gi|7507774|pir||T16860 hypothetical protein T13C2.4 - Caenorhabd... 259 1e-66
gi|7494499|pir||T31330 head-activator binding protein precursor ... 258 3e-66
gi|26332673|dbj|BAC30054.1| unnamed protein product [Mus musculus] 253 1e-64
gi|50747938|ref|XP_421047.1| PREDICTED: similar to Lipoprotein R... 248 4e-63
gi|39595186|emb|CAE60223.1| Hypothetical protein CBG03794 [Caeno... 240 6e-61
gi|15425721|dbj|BAB64338.1| vitellogenin receptor [Conger myrias... 238 2e-60
gi|25152990|ref|NP_500815.2| yolk receptor, LDL receptor superfa... 238 4e-60
gi|4097463|gb|AAD09363.1| lipoprotein receptor precursor [Caenor... 236 1e-59
gi|7511475|pir||T37475 lipoprotein receptor precursor - Caenorha... 236 1e-59
gi|28502930|gb|AAH47187.1| Zgc:55792 protein [Danio rerio] 236 2e-59
gi|5919205|gb|AAD56241.1| yolk receptor RME-2 [Caenorhabditis el... 234 4e-59
gi|46561850|gb|AAT01142.1| proteoliaisin [Lytechinus variegatus] 233 1e-58
gi|3114861|emb|CAA72732.1| putative LR11/gp250 receptor protein ... 226 1e-56
gi|40288425|gb|AAR84237.1| truncated epidermal growth factor (be... 224 5e-56
gi|4503491|ref|NP_001954.1| epidermal growth factor (beta-urogas... 224 5e-56
gi|47224917|emb|CAG06487.1| unnamed protein product [Tetraodon n... 223 1e-55
gi|26326125|dbj|BAC26806.1| unnamed protein product [Mus musculus] 223 1e-55
gi|14009441|dbj|BAB47391.1| epidermal growth factor [Felis catus] 222 2e-55
gi|6978797|ref|NP_036974.1| epidermal growth factor [Rattus norv... 222 2e-55
gi|47522862|ref|NP_999185.1| epidermal growth factor [Sus scrofa... 222 2e-55
gi|46561848|gb|AAT01141.1| proteoliaisin [Strongylocentrotus pur... 221 5e-55
gi|13537341|dbj|BAB40599.1| epidermal growth factor [Canis famil... 220 7e-55
gi|38303863|gb|AAH62030.1| Egf protein [Rattus norvegicus] 219 1e-54
gi|7512093|pir||T30272 hypothetical protein - sea urchin (Strong... 219 1e-54
gi|3047267|gb|AAC14024.1| epidermal growth factor precursor [Sus... 218 3e-54
gi|47216973|emb|CAG04915.1| unnamed protein product [Tetraodon n... 216 1e-53
gi|46561854|gb|AAT01144.1| soft fertilization envelope protein 9... 213 8e-53
gi|24639354|ref|NP_726814.1| CG7981-PE [Drosophila melanogaster]... 213 1e-52
gi|24158420|ref|NP_524643.2| CG7981-PA [Drosophila melanogaster]... 213 1e-52
gi|24639352|ref|NP_726813.1| CG7981-PC [Drosophila melanogaster]... 213 1e-52
gi|24639358|ref|NP_726816.1| CG7981-PB [Drosophila melanogaster]... 213 1e-52
gi|47604934|ref|NP_001001292.1| epidermal growth factor precurso... 212 2e-52
gi|50746773|ref|XP_420648.1| PREDICTED: similar to epidermal gro... 211 4e-52
gi|1169995|sp|P46023|GPCR_LYMST G-protein coupled receptor GRL10... 211 5e-52
gi|223684|prf||0907234A epidermal growth factor precursor 208 3e-51
gi|38174492|gb|AAH60741.1| Epidermal growth factor [Mus musculus] 208 3e-51
gi|6753732|ref|NP_034243.1| epidermal growth factor [Mus musculu... 208 3e-51
gi|50801|emb|CAA24115.1| unnamed protein product [Mus musculus] 208 3e-51
gi|17389248|gb|AAH17681.1| Egf protein [Mus musculus] 208 3e-51
gi|47216575|emb|CAG00610.1| unnamed protein product [Tetraodon n... 206 2e-50
gi|50747936|ref|XP_421046.1| PREDICTED: similar to low density l... 204 7e-50
gi|46561852|gb|AAT01143.1| soft fertilization envelope protein 1... 204 7e-50
gi|33879163|gb|AAH21204.1| Unknown (protein for IMAGE:4110815) [... 202 1e-49
gi|34863171|ref|XP_217115.2| similar to gp250 precursor [Rattus ... 199 1e-48
gi|24639356|ref|NP_726815.1| CG7981-PD [Drosophila melanogaster]... 199 2e-48
gi|6946671|emb|CAB72286.1| EG:BACR25B3.1 [Drosophila melanogaster] 199 2e-48
gi|46947106|gb|AAB02256.2| SFE1 [Strongylocentrotus purpuratus] 193 9e-47
gi|7512094|pir||T30274 proteoliaisin - sea urchin (Strongylocent... 193 9e-47
gi|26330916|dbj|BAC29188.1| unnamed protein product [Mus musculus] 187 5e-45
gi|50751224|ref|XP_429288.1| PREDICTED: hypothetical protein XP_... 182 3e-43
gi|14488690|pdb|1IJQ|A Chain A, Crystal Structure Of The Ldl Rec... 180 8e-43
gi|32563562|ref|NP_872279.1| corin [Rattus norvegicus] >gnl|BL_O... 179 2e-42
gi|47226733|emb|CAG07892.1| unnamed protein product [Tetraodon n... 179 2e-42
gi|41053668|ref|NP_956782.1| hypothetical protein MGC63759 [Dani... 176 2e-41
gi|8394057|ref|NP_058565.1| corin; low density lipoprotein-relat... 173 1e-40
gi|50747079|ref|XP_426340.1| PREDICTED: similar to Atrial natriu... 172 2e-40
gi|47227475|emb|CAG04623.1| unnamed protein product [Tetraodon n... 172 2e-40
gi|42658662|ref|XP_379966.1| similar to KIAA2036 protein [Homo s... 172 2e-40
gi|47210424|emb|CAF92449.1| unnamed protein product [Tetraodon n... 168 3e-39
gi|31223187|ref|XP_317275.1| ENSANGP00000021850 [Anopheles gambi... 167 5e-39
gi|45387869|ref|NP_991294.1| epidermal growth factor precursor [... 166 1e-38
gi|32565544|ref|NP_498237.2| low density lipoprotein-receptor, c... 166 2e-38
gi|25395755|pir||B88465 protein B0244.8 [imported] - Caenorhabdi... 166 2e-38
gi|47217533|emb|CAG02460.1| unnamed protein product [Tetraodon n... 165 3e-38
gi|15291287|gb|AAK92912.1| GH14506p [Drosophila melanogaster] 164 8e-38
gi|17554424|ref|NP_498537.1| low density lipoprotein-receptor, c... 162 2e-37
gi|3808095|emb|CAA69867.1| SCO-spondin [Bos taurus] 162 3e-37
gi|28195400|ref|NP_777131.1| SCO-spondin [Bos taurus] >gnl|BL_OR... 162 3e-37
gi|39583862|emb|CAE63952.1| Hypothetical protein CBG08534 [Caeno... 161 5e-37
gi|50796505|ref|XP_428198.1| PREDICTED: similar to AM2 receptor,... 160 6e-37
gi|30424661|ref|NP_775604.1| subcommissural organ spondin; SCO-s... 158 4e-36
gi|13878447|sp|Q9Y5Q5|CORI_HUMAN Atrial natriuteric peptide-conv... 155 2e-35
gi|6739500|gb|AAF27280.1| LDLR-FUT fusion protein [Homo sapiens] 155 3e-35
gi|29244926|ref|NP_006578.2| corin; heart specific serine protei... 155 3e-35
gi|48120148|ref|XP_393220.1| similar to EG:BACR25B3.1 [Apis mell... 153 1e-34
gi|45552547|ref|NP_995796.1| CG12908-PB [Drosophila melanogaster... 152 2e-34
gi|24652408|ref|NP_610575.1| CG12908-PA [Drosophila melanogaster... 152 2e-34
gi|23477350|gb|AAN34647.1| LDL receptor [Oncorhynchus mykiss] 151 5e-34
gi|37360934|dbj|BAC98376.1| KIAA2036 protein [Homo sapiens] 150 7e-34
gi|42657977|ref|XP_376719.1| similar to KIAA2036 protein [Homo s... 150 7e-34
gi|7513560|pir||JE0373 low density lipoprotein receptor related ... 150 1e-33
gi|2134852|pir||I53413 calcium sensor protein - human (fragment)... 149 1e-33
gi|26331372|dbj|BAC29416.1| unnamed protein product [Mus musculus] 146 2e-32
gi|418881|pir||S31213 nidogen precursor - sea squirt (Halocynthi... 145 2e-32
gi|45124835|emb|CAF33425.1| SCO-spondin [Rattus norvegicus] 145 3e-32
gi|7271899|gb|AAF44680.1| nidogen 1; entactin [Gallus gallus] 144 5e-32
gi|71431|pir||MMHUND nidogen precursor - human 144 5e-32
gi|28374139|gb|AAH45606.1| NID protein [Homo sapiens] 144 5e-32
gi|602467|gb|AAA57261.1| nidogen 144 5e-32
gi|48095607|ref|XP_392328.1| similar to ENSANGP00000021850 [Apis... 144 6e-32
gi|4505395|ref|NP_002499.1| nidogen (enactin); Nidogen; nidogen ... 144 8e-32
gi|1155011|emb|CAA57709.1| nidogen [Homo sapiens] 144 8e-32
gi|47230766|emb|CAF99959.1| unnamed protein product [Tetraodon n... 142 2e-31
gi|53384|emb|CAA32642.1| unnamed protein product [Mus musculus] 142 3e-31
gi|6754854|ref|NP_035047.1| nidogen 1; entactin 1 [Mus musculus]... 142 3e-31
gi|26351327|dbj|BAC39300.1| unnamed protein product [Mus musculus] 142 3e-31
gi|34866738|ref|XP_236755.2| similar to testis protein TEX15 [Ra... 139 3e-30
gi|39593249|emb|CAE64719.1| Hypothetical protein CBG09505 [Caeno... 138 5e-30
gi|34876253|ref|XP_213954.2| nidogen (entactin) [Rattus norvegicus] 137 8e-30
gi|17562774|ref|NP_506228.1| NIDogen, basement membrane protein ... 136 2e-29
gi|34861443|ref|XP_345311.1| similar to lipoprotein receptor-rel... 134 7e-29
gi|47217532|emb|CAG02459.1| unnamed protein product [Tetraodon n... 130 9e-28
gi|34810643|pdb|1NPE|A Chain A, Crystal Structure Of NidogenLAMI... 128 4e-27
gi|23273447|gb|AAH35608.1| NID2 protein [Homo sapiens] 127 6e-27
gi|33469989|ref|NP_031387.2| nidogen 2; osteonidogen [Homo sapiens] 127 6e-27
gi|47550925|ref|NP_999636.1| cortical granule serine protease 1 ... 127 1e-26
gi|2252518|emb|CAA57882.1| low-density lipoprotein receptor-rela... 127 1e-26
gi|8928569|sp|Q14112|NID2_HUMAN Nidogen-2 precursor (NID-2) (Ost... 126 1e-26
gi|2135868|pir||G00043 osteonidogen - human >gnl|BL_ORD_ID|15877... 126 1e-26
gi|31208927|ref|XP_313430.1| ENSANGP00000020211 [Anopheles gambi... 124 9e-26
gi|31241309|ref|XP_321085.1| ENSANGP00000007871 [Anopheles gambi... 122 2e-25
gi|47209610|emb|CAF89594.1| unnamed protein product [Tetraodon n... 122 2e-25
gi|50760033|ref|XP_417872.1| PREDICTED: similar to suppression o... 122 3e-25
gi|34869048|ref|XP_238622.2| similar to Nidogen 2 [Rattus norveg... 121 6e-25
gi|17537743|ref|NP_497048.1| low density lipoprotein receptor (2... 120 7e-25
gi|6679058|ref|NP_032721.1| nidogen 2; entactin 2 [Mus musculus]... 120 7e-25
gi|30851203|gb|AAH52593.1| Unknown (protein for IMAGE:6575284) [... 120 1e-24
gi|28175681|gb|AAH45107.1| Unknown (protein for IMAGE:4859182) [... 120 1e-24
gi|32451977|gb|AAH54746.1| Nidogen 2 [Mus musculus] >gnl|BL_ORD_... 119 2e-24
gi|18535663|gb|AAL71853.1| nidogen 2 protein [Mus musculus] 119 2e-24
gi|23592218|emb|CAD21572.3| nidogen-2 [Mus musculus] 119 2e-24
gi|49900216|gb|AAH76994.1| Unknown (protein for MGC:89623) [Xeno... 119 2e-24
gi|48109148|ref|XP_396216.1| similar to ENSANGP00000007871 [Apis... 118 5e-24
gi|47846181|emb|CAE51322.1| basement membrane-specific heparan s... 118 5e-24
gi|50807426|ref|XP_428911.1| PREDICTED: similar to SCO-spondin, ... 117 6e-24
gi|49257232|gb|AAH71077.1| St14-A-prov protein [Xenopus laevis] 117 8e-24
gi|9757702|dbj|BAB08218.1| homolog of human MT-SP1 [Xenopus laevis] 117 8e-24
gi|31213594|ref|XP_315726.1| ENSANGP00000004359 [Anopheles gambi... 117 8e-24
gi|50748950|ref|XP_421471.1| PREDICTED: similar to osteonidogen ... 117 1e-23
gi|16758444|ref|NP_446087.1| suppression of tumorigenicity 14; s... 115 2e-23
gi|47229074|emb|CAG03826.1| unnamed protein product [Tetraodon n... 115 2e-23
gi|32698824|ref|NP_872298.1| hypothetical protein DKFZp434O0213 ... 115 2e-23
gi|48115062|ref|XP_393173.1| similar to Hypothetical protein CBG... 115 3e-23
gi|39582692|emb|CAE65898.1| Hypothetical protein CBG11065 [Caeno... 114 5e-23
gi|31241665|ref|XP_321263.1| ENSANGP00000018359 [Anopheles gambi... 112 2e-22
gi|48097368|ref|XP_393762.1| similar to ENSANGP00000020384 [Apis... 112 3e-22
gi|7363445|ref|NP_035306.2| suppression of tumorigenicity 14 (co... 111 6e-22
gi|34398400|gb|AAQ67268.1| CG31217 [Drosophila virilis] 111 6e-22
gi|47212882|emb|CAF90331.1| unnamed protein product [Tetraodon n... 111 6e-22
gi|50741038|ref|XP_419556.1| PREDICTED: similar to nidogen 1; en... 110 8e-22
gi|12249015|dbj|BAB20376.1| prostamin [Homo sapiens] 110 1e-21
gi|11415040|ref|NP_068813.1| matriptase; suppression of tumorige... 110 1e-21
gi|10257390|gb|AAG15395.1| serine protease TADG15 [Homo sapiens] 110 1e-21
gi|17390323|gb|AAH18146.1| ST14 protein [Homo sapiens] 110 1e-21
gi|34782939|gb|AAH05826.2| ST14 protein [Homo sapiens] 110 1e-21
gi|10179932|gb|AAG13949.1| serine protease SNC19 [Homo sapiens] 110 1e-21
gi|48104878|ref|XP_395858.1| similar to lipophorin receptor [Api... 109 2e-21
gi|39582691|emb|CAE65897.1| Hypothetical protein CBG11064 [Caeno... 108 3e-21
gi|17536619|ref|NP_497045.1| basement membrane proteoglycan (2O9... 108 3e-21
gi|17536623|ref|NP_497047.1| basement membrane proteoglycan (127... 108 3e-21
gi|50507819|emb|CAH04704.1| Hypothetical protein ZC101.2f [Caeno... 108 3e-21
gi|30179887|sp|Q06561|UN52_CAEEL Basement membrane proteoglycan ... 108 3e-21
gi|7305525|ref|NP_038465.1| suppression of tumorigenicity; C8200... 108 3e-21
gi|17536621|ref|NP_497046.1| basement membrane proteoglycan (2O9... 108 3e-21
gi|34849518|gb|AAH58345.1| C820005L12Rik protein [Mus musculus] 108 3e-21
gi|289722|gb|AAA28156.1| basement membrane proteoglycan 108 3e-21
gi|27370214|ref|NP_766402.1| RIKEN cDNA C820005L12 [Mus musculus... 108 3e-21
gi|28557796|ref|NP_777562.1| hypothetical protein LOC143458 [Hom... 108 4e-21
gi|47210047|emb|CAF92888.1| unnamed protein product [Tetraodon n... 108 4e-21
gi|27769272|gb|AAH42754.1| LOC143458 protein [Homo sapiens] 108 4e-21
gi|46396499|sp|Q9BE74|LR12_MACFA Low-density lipoprotein recepto... 108 5e-21
gi|47216714|emb|CAG00988.1| unnamed protein product [Tetraodon n... 108 5e-21
gi|32264589|gb|AAP78740.1| LDL-like [Branchiostoma floridae] 108 5e-21
gi|46849814|ref|NP_849217.1| expressed sequence AI194318 [Mus mu... 108 5e-21
gi|26328037|dbj|BAC27759.1| unnamed protein product [Mus musculus] 108 5e-21
gi|969091|gb|AAA84413.1| LDL receptor-like repeat; orfIa 107 7e-21
gi|17554122|ref|NP_499254.1| transmembrane cell adhesion recepto... 107 7e-21
gi|31322550|gb|AAO52676.1| TFP250 [Eimeria maxima] 107 7e-21
gi|48137845|ref|XP_396820.1| similar to ENSANGP00000018359 [Apis... 107 1e-20
gi|50731832|ref|XP_418378.1| PREDICTED: similar to Low-density l... 107 1e-20
gi|34866097|ref|XP_235261.2| similar to RIKEN cDNA C820005L12 [R... 106 1e-20
gi|1172451|sp|Q05793|PGBM_MOUSE Basement membrane-specific hepar... 106 2e-20
gi|47225569|emb|CAG12052.1| unnamed protein product [Tetraodon n... 105 2e-20
gi|47225217|emb|CAF98844.1| unnamed protein product [Tetraodon n... 105 3e-20
gi|1709335|sp|P21783|NOTC_XENLA Neurogenic locus notch protein h... 105 3e-20
gi|50746637|ref|XP_420587.1| PREDICTED: similar to Low-density l... 105 4e-20
gi|47213696|emb|CAF94589.1| unnamed protein product [Tetraodon n... 104 6e-20
gi|12621134|ref|NP_075244.1| MEGF6 [Rattus norvegicus] >gnl|BL_O... 104 7e-20
gi|34872189|ref|XP_233606.2| similar to Basement membrane-specif... 104 7e-20
gi|24647518|ref|NP_536776.2| CG31217-PA [Drosophila melanogaster... 103 9e-20
gi|31215890|ref|XP_316120.1| ENSANGP00000020384 [Anopheles gambi... 103 1e-19
gi|539611|pir||A38096 perlecan precursor - human >gnl|BL_ORD_ID|... 103 2e-19
gi|24212664|sp|P98160|PGBM_HUMAN Basement membrane-specific hepa... 103 2e-19
gi|7427517|ref|NP_005520.2| heparan sulfate proteoglycan 2; hepa... 103 2e-19
gi|11602963|emb|CAC18534.1| heparan sulfate proteoglycan perleca... 103 2e-19
gi|47227882|emb|CAG09045.1| unnamed protein product [Tetraodon n... 102 2e-19
gi|104252|pir||A35844 Xotch protein - African clawed frog 102 2e-19
gi|24659436|ref|NP_523947.2| CG10129-PA [Drosophila melanogaster... 102 3e-19
gi|1362621|pir||A57096 nudel protein precursor - fruit fly (Dros... 102 3e-19
gi|6746588|gb|AAF27637.1| ecdysone-inducible gene E1 [Drosophila... 102 4e-19
gi|24660872|ref|NP_524849.2| CG32356-PA [Drosophila melanogaster... 102 4e-19
gi|28558748|ref|NP_726551.2| CG31999-PA [Drosophila melanogaster... 102 4e-19
gi|50753796|ref|XP_414135.1| PREDICTED: similar to low density l... 100 8e-19
gi|47187500|emb|CAF87269.1| unnamed protein product [Tetraodon n... 100 1e-18
gi|34857421|ref|XP_345407.1| hypothetical protein XP_345406 [Rat... 100 1e-18
gi|38079068|ref|XP_149548.3| similar to MEGF6 [Mus musculus] 99 2e-18
gi|31208929|ref|XP_313431.1| ENSANGP00000024003 [Anopheles gambi... 99 3e-18
gi|48097480|ref|XP_393795.1| similar to fibrillin-2 [Apis mellif... 98 5e-18
gi|50792921|ref|XP_427922.1| PREDICTED: similar to alpha-2-macro... 98 7e-18
gi|14148971|emb|CAC39104.1| LDL receptor [Anopheles gambiae] 98 7e-18
gi|50754533|ref|XP_425156.1| PREDICTED: similar to Fbln2 protein... 97 9e-18
gi|42761510|gb|AAS45328.1| similar to Mus musculus (Mouse). Late... 97 9e-18
gi|18029258|gb|AAL56436.1| similar to fibrillin [Oikopleura dioica] 97 1e-17
gi|685200|gb|AAA91336.1| fibrillin 97 1e-17
gi|50732087|ref|XP_418472.1| PREDICTED: similar to SCO-spondin [... 97 2e-17
gi|39590594|emb|CAE64964.1| Hypothetical protein CBG09798 [Caeno... 96 2e-17
gi|47211424|emb|CAF92700.1| unnamed protein product [Tetraodon n... 96 2e-17
gi|50732393|ref|XP_418614.1| PREDICTED: similar to apical early ... 96 3e-17
gi|50799271|ref|XP_428400.1| PREDICTED: similar to low density l... 96 3e-17
gi|6679757|ref|NP_032018.1| fibulin 2 [Mus musculus] >gnl|BL_ORD... 96 3e-17
gi|4959705|gb|AAD34456.1| fibulin-2 [Mus musculus] 96 3e-17
gi|34857664|ref|XP_232197.2| similar to fibulin-2 [Rattus norveg... 95 4e-17
gi|23505417|gb|AAN05436.1| fibulin 2 [Homo sapiens] 95 6e-17
gi|13365869|dbj|BAB39320.1| hypothetical protein [Macaca fascicu... 94 7e-17
gi|31199179|ref|XP_308537.1| ENSANGP00000015896 [Anopheles gambi... 94 7e-17
gi|30353774|gb|AAH51690.1| Fibulin 2, precursor [Homo sapiens] 94 1e-16
gi|4503665|ref|NP_001989.1| fibulin 2 precursor; Fibulin-2 [Homo... 94 1e-16
gi|13529413|gb|AAH05443.1| Fbln2 protein [Mus musculus] 94 1e-16
gi|46395624|sp|O75095|EFL3_HUMAN Multiple EGF-like-domain protei... 93 2e-16
gi|50760898|ref|XP_418173.1| PREDICTED: similar to Fibrillin 2 p... 93 2e-16
gi|41107704|ref|XP_031401.4| EGF-like-domain, multiple 3 [Homo s... 93 2e-16
gi|13399179|emb|CAC34726.1| microneme protein 4 [Eimeria tenella] 92 3e-16
gi|39592208|emb|CAE75429.1| Hypothetical protein CBG23422 [Caeno... 92 4e-16
gi|47210094|emb|CAF90826.1| unnamed protein product [Tetraodon n... 92 4e-16
gi|48106706|ref|XP_396146.1| similar to lipophorin receptor [Api... 92 4e-16
gi|17562608|ref|NP_506072.1| low density lipoprotein Receptor X-... 92 4e-16
gi|4884120|emb|CAB43267.1| hypothetical protein [Homo sapiens] 92 4e-16
gi|23505429|gb|AAN05435.1| fibulin 2 [Homo sapiens] 92 4e-16
gi|48110771|ref|XP_396277.1| similar to CG9138-PA [Apis mellifera] 92 5e-16
gi|47211546|emb|CAF96111.1| unnamed protein product [Tetraodon n... 91 6e-16
gi|39588424|emb|CAE72775.1| Hypothetical protein CBG20030 [Caeno... 91 8e-16
gi|13929178|ref|NP_114013.1| fibrillin-1 [Rattus norvegicus] >gn... 91 8e-16
gi|3688648|gb|AAC62317.1| mutant fibrillin-1 [Mus musculus] 91 8e-16
gi|47209733|emb|CAF90683.1| unnamed protein product [Tetraodon n... 91 1e-15
gi|50752971|ref|XP_413815.1| PREDICTED: similar to fibrillin [Ga... 90 1e-15
gi|2947316|gb|AAC05388.1| fibulin-1, isoform C precursor [Gallus... 90 1e-15
gi|45383790|ref|NP_989496.1| fibulin 1 [Gallus gallus] >gnl|BL_O... 90 1e-15
gi|50761388|ref|XP_424715.1| PREDICTED: similar to Fibrillin 2 p... 90 1e-15
gi|47230658|emb|CAF99851.1| unnamed protein product [Tetraodon n... 90 1e-15
gi|17540764|ref|NP_501695.1| FiBuLin, extracellular matrix prote... 90 2e-15
gi|17540768|ref|NP_501693.1| FiBuLin, extracellular matrix prote... 90 2e-15
gi|47212260|emb|CAG06344.1| unnamed protein product [Tetraodon n... 90 2e-15
gi|24650519|ref|NP_651533.1| CG6124-PA [Drosophila melanogaster]... 89 2e-15
gi|6679759|ref|NP_032019.1| fibrillin 1; tight skin [Mus musculu... 89 2e-15
gi|27807269|ref|NP_777128.1| tenascin X [Bos taurus] >gnl|BL_ORD... 89 2e-15
gi|47220868|emb|CAG03075.1| unnamed protein product [Tetraodon n... 89 3e-15
gi|11346361|pir||T43210 fibulin-1D precursor - Caenorhabditis el... 89 4e-15
gi|1619307|emb|CAA69877.1| gp330 [Mus musculus] 89 4e-15
gi|1857988|gb|AAB48531.1| fibrillin-1 [Gallus gallus] 89 4e-15
gi|24653479|ref|NP_610911.1| CG6553-PA [Drosophila melanogaster]... 88 5e-15
gi|42662449|ref|XP_376001.1| similar to low density lipoprotein ... 88 7e-15
gi|17543898|ref|NP_502737.1| MEGF6 (4P83) [Caenorhabditis elegan... 88 7e-15
gi|6753826|ref|NP_034311.1| fibrillin 2; syndatyly ems [Mus musc... 88 7e-15
gi|39596643|emb|CAE63262.1| Hypothetical protein CBG07635 [Caeno... 87 9e-15
gi|13929180|ref|NP_114014.1| fibrillin-2 [Rattus norvegicus] >gn... 87 9e-15
gi|28574998|ref|NP_612113.2| CG12086-PA [Drosophila melanogaster... 87 1e-14
gi|4503667|ref|NP_001990.1| fibrillin 2 (congenital contractural... 87 1e-14
gi|627438|pir||A54105 fibrillin-2 precursor - human 87 1e-14
gi|41946838|gb|AAH66066.1| Unknown (protein for MGC:91355) [Mus ... 87 1e-14
gi|45550554|ref|NP_648137.2| CG7526-PA [Drosophila melanogaster]... 87 1e-14
gi|47223349|emb|CAG04210.1| unnamed protein product [Tetraodon n... 87 2e-14
gi|46249414|ref|NP_996826.1| latent transforming growth factor b... 86 2e-14
gi|19909128|gb|AAM03124.1| transforming growth factor-beta bindi... 86 2e-14
gi|135691|sp|P22064|LTBS_HUMAN Latent transforming growth factor... 86 2e-14
gi|46249412|ref|NP_000618.2| latent transforming growth factor b... 86 2e-14
gi|17551536|ref|NP_510507.1| receptor rabit (XP707) [Caenorhabd... 86 2e-14
gi|20138588|sp|Q14766|LTBL_HUMAN Latent transforming growth fact... 86 2e-14
gi|27503150|gb|AAH42143.1| Similar to hypothetical protein FLJ32... 86 3e-14
gi|22749431|ref|NP_689931.1| hypothetical protein FLJ32009 [Homo... 86 3e-14
gi|30851299|gb|AAH52564.1| FLJ32009 protein [Homo sapiens] >gnl|... 86 3e-14
gi|37551291|ref|XP_295865.2| similar to apical early endosomal g... 86 3e-14
gi|28175657|gb|AAH45220.1| Matn2-prov protein [Xenopus laevis] 86 3e-14
gi|7459676|pir||A47221 fibrillin 1 precursor - human (fragment) 86 3e-14
gi|227918|prf||1713408A fibrillin 86 3e-14
gi|1335064|emb|CAA45118.1| fibrillin [Homo sapiens] 86 3e-14
gi|24430141|ref|NP_000129.2| fibrillin 1 [Homo sapiens] 86 3e-14
gi|46559358|dbj|BAD16739.1| fibrillin 1 [Homo sapiens] 86 3e-14
gi|544279|sp|P35555|FBN1_HUMAN Fibrillin 1 precursor >gnl|BL_ORD... 86 3e-14
gi|38084854|ref|XP_129157.2| RIKEN cDNA 1300015B04 [Mus musculus] 85 5e-14
gi|30580425|sp|Q8MJJ9|FBL1_CERAE Fibulin-1C >gnl|BL_ORD_ID|11846... 85 5e-14
gi|34867535|ref|XP_243637.2| similar to Fbln1 protein [Rattus no... 85 5e-14
gi|28175169|gb|AAH43473.1| 1300015B04Rik protein [Mus musculus] 85 5e-14
gi|39581624|emb|CAE71745.1| Hypothetical protein CBG18730 [Caeno... 85 5e-14
gi|9757700|dbj|BAB08217.1| embryonic serine protease-2 [Xenopus ... 85 5e-14
gi|41058059|gb|AAR99095.1| RE61404p [Drosophila melanogaster] 85 6e-14
gi|34861875|ref|XP_219579.2| similar to hypothetical protein FLJ... 85 6e-14
gi|47221710|emb|CAG10182.1| unnamed protein product [Tetraodon n... 84 1e-13
gi|7513651|pir||S78040 fibulin, splice form C precursor - mouse 84 1e-13
gi|32490559|ref|NP_054764.2| low density lipoprotein receptor-re... 84 1e-13
gi|40787709|gb|AAH64901.1| Unknown (protein for IMAGE:6009130) [... 84 1e-13
gi|479627|pir||S34968 fibulin, splice form D precursor - mouse 84 1e-13
gi|6753822|ref|NP_034310.1| fibulin 1; BM-90/fibulin extracellul... 84 1e-13
gi|21740333|emb|CAD39174.1| hypothetical protein [Homo sapiens] 84 1e-13
gi|34734066|ref|NP_006477.2| fibulin 1 isoform D [Homo sapiens] 84 1e-13
gi|1621019|gb|AAB17099.1| fibulin-1D [Homo sapiens] >gnl|BL_ORD_... 84 1e-13
gi|30581038|sp|P23142|FBL1_HUMAN Fibulin-1 precursor 84 1e-13
gi|13928672|ref|NP_112453.1| tenascin XB [Mus musculus] >gnl|BL_... 84 1e-13
gi|26352065|dbj|BAC39669.1| unnamed protein product [Mus musculus] 84 1e-13
gi|13938049|gb|AAH07140.1| Fbln1 protein [Mus musculus] >gnl|BL_... 84 1e-13
gi|31415|emb|CAA37770.1| fibulin-1 A [Homo sapiens] 84 1e-13
gi|34734068|ref|NP_006478.2| fibulin 1 isoform A precursor [Homo... 84 1e-13
gi|18490682|gb|AAH22497.1| Fibulin 1, isoform C precursor [Homo ... 84 1e-13
gi|106018|pir||C36346 fibulin 1 precursor, splice form C - human... 84 1e-13
gi|34734062|ref|NP_001987.2| fibulin 1 isoform C precursor [Homo... 84 1e-13
gi|45552029|ref|NP_787974.2| CG33196-PB [Drosophila melanogaster... 84 1e-13
gi|22761800|dbj|BAC11705.1| unnamed protein product [Homo sapiens] 84 1e-13
gi|30581063|sp|Q08879|FBL1_MOUSE Fibulin-1 precursor (Basement-m... 84 1e-13
gi|34734064|ref|NP_006476.2| fibulin 1 isoform B precursor [Homo... 84 1e-13
gi|106017|pir||B36346 fibulin 1 precursor, splice form B - human... 84 1e-13
gi|10441928|gb|AAG17241.1| unknown [Homo sapiens] 84 1e-13
gi|7511304|pir||T34513 hypothetical protein ZK783.1 - Caenorhabd... 84 1e-13
>gi|17508271|ref|NP_492127.1| EGF motif related, Low-density lipoprotein
Receptor Related (lrp-1) [Caenorhabditis elegans]
gi|1708868|sp|Q04833|LRP_CAEEL Low-density lipoprotein receptor-related
protein precursor (LRP)
gi|1078879|pir||A47437 LDL-receptor-related protein - Caenorhabditis
elegans
gi|156360|gb|AAA28105.1| LDL receptor-related protein [Caenorhabditis
elegans]
gi|3876533|emb|CAA98124.1| Hypothetical protein F29D11.1
[Caenorhabditis elegans]
Length = 4753
Score = 9651 bits (25043), Expect = 0.0
Identities = 4574/4753 (96%), Positives = 4574/4753 (96%)
Frame = +1
Query: 1 MILRLLIFTALAVTTANSSTRQQSTFHSIQVDSPPSVRSRIISASVNTASSVCNENDFRC 180
MILRLLIFTALAVTTANSSTRQQSTFHSIQVDSPPSVRSRIISASVNTASSVCNENDFRC
Sbjct: 1 MILRLLIFTALAVTTANSSTRQQSTFHSIQVDSPPSVRSRIISASVNTASSVCNENDFRC 60
Query: 181 NDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAEYQRCDNIT 360
NDGKCIRTEW PHPGCKSDQWQCDTYTWHSVSCIAEYQRCDNIT
Sbjct: 61 NDGKCIRTEWKCDGSGDCSDGEDEKDCPHPGCKSDQWQCDTYTWHSVSCIAEYQRCDNIT 120
Query: 361 DCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHT 540
DCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHT
Sbjct: 121 DCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHT 180
Query: 541 ACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKF 720
ACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKF
Sbjct: 181 ACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKF 240
Query: 721 RCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQN 900
RCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQN
Sbjct: 241 RCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQN 300
Query: 901 LCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFT 1080
LCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFT
Sbjct: 301 LCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFT 360
Query: 1081 CSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKL 1260
CSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKL
Sbjct: 361 CSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKL 420
Query: 1261 ASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDW 1440
ASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDW
Sbjct: 421 ASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDW 480
Query: 1441 ITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTNQLKLEAAA 1620
ITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTNQLKLEAAA
Sbjct: 481 ITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTNQLKLEAAA 540
Query: 1621 MDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVP 1800
MDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVP
Sbjct: 541 MDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVP 600
Query: 1801 HPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPG 1980
HPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPG
Sbjct: 601 HPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPG 660
Query: 1981 QSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGKRCIDSIDYLLF 2160
QSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGKRCIDSIDYLLF
Sbjct: 661 QSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGKRCIDSIDYLLF 720
Query: 2161 SSNKIVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYR 2340
SSNKIVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYR
Sbjct: 721 SSNKIVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYR 780
Query: 2341 IRPDGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRR 2520
IRPDGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRR
Sbjct: 781 IRPDGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRR 840
Query: 2521 QLITELRDPVSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDF 2700
QLITELRDPVSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDF
Sbjct: 841 QLITELRDPVSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDF 900
Query: 2701 AENRLCWGDTLLKTISCMDFDGKNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHK 2880
AENRLCWGDTLLKTISCMDFDGKNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHK
Sbjct: 901 AENRLCWGDTLLKTISCMDFDGKNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHK 960
Query: 2881 KNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPN 3060
KNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPN
Sbjct: 961 KNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPN 1020
Query: 3061 ELEAKCACRQGFMINKENNHSCQKDPAEKIEQLCSSNSTQFQCKNGRCIPKEWKCDGEND 3240
ELEAKCACRQGFMINKENNHSCQKDPAEKIEQLCSSNSTQFQCKNGRCIPKEWKCDGEND
Sbjct: 1021 ELEAKCACRQGFMINKENNHSCQKDPAEKIEQLCSSNSTQFQCKNGRCIPKEWKCDGEND 1080
Query: 3241 CLDESDEIDEKGDKCFHETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKD 3420
CLDESDEIDEKGDKCFHETECAENTIKCRNTKKCIPAQ VKYCKD
Sbjct: 1081 CLDESDEIDEKGDKCFHETECAENTIKCRNTKKCIPAQYGCDGDNDCGDYSDEDVKYCKD 1140
Query: 3421 GQKPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNATCAANQFSCANGRCI 3600
GQKPVCAAKKFQCDNHRCIPEQWK EKLEMCGNATCAANQFSCANGRCI
Sbjct: 1141 GQKPVCAAKKFQCDNHRCIPEQWKCDSDNDCGDGSDEKLEMCGNATCAANQFSCANGRCI 1200
Query: 3601 PIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQCVPLRNHXXXXXXXXXXXXX 3780
PIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQCVPLRNH
Sbjct: 1201 PIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQCVPLRNHCDGQSDCEDGSDE 1260
Query: 3781 XXXAVTAESCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKC 3960
AVTAESCTPDQFKCVSSGLCIPASWK SDEPKFGCTSGRQCSSDQFKC
Sbjct: 1261 DSCAVTAESCTPDQFKCVSSGLCIPASWKCDGQQDCDDGSDEPKFGCTSGRQCSSDQFKC 1320
Query: 3961 GNGRCILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLC 4140
GNGRCILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLC
Sbjct: 1321 GNGRCILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLC 1380
Query: 4141 DGKTHCPGGTDEGGRCARDLCSADRAGCSFKCHNSPNGPICSCPFGEQLVNKTKCEPENE 4320
DGKTHCPGGTDEGGRCARDLCSADRAGCSFKCHNSPNGPICSCPFGEQLVNKTKCEPENE
Sbjct: 1381 DGKTHCPGGTDEGGRCARDLCSADRAGCSFKCHNSPNGPICSCPFGEQLVNKTKCEPENE 1440
Query: 4321 CLDSSSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHK 4500
CLDSSSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHK
Sbjct: 1441 CLDSSSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHK 1500
Query: 4501 LDNWHTFGAIVENAIALAWDSLTDRIYWSDIREKKILSANRNGTNATVFIADGLDITEGI 4680
LDNWHTFGAIVENAIALAWDSLTDRIYWSDIREKKILSANRNGTNATVFIADGLDITEGI
Sbjct: 1501 LDNWHTFGAIVENAIALAWDSLTDRIYWSDIREKKILSANRNGTNATVFIADGLDITEGI 1560
Query: 4681 ALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQ 4860
ALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQ
Sbjct: 1561 ALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQ 1620
Query: 4861 NPCIERASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQV 5040
NPCIERASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQV
Sbjct: 1621 NPCIERASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQV 1680
Query: 5041 LASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHP 5220
LASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHP
Sbjct: 1681 LASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHP 1740
Query: 5221 VLQPVIKNNPCSTNPCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTN 5400
VLQPVIKNNPCSTNPCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTN
Sbjct: 1741 VLQPVIKNNPCSTNPCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTN 1800
Query: 5401 VFGIEMNSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDS 5580
VFGIEMNSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDS
Sbjct: 1801 VFGIEMNSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDS 1860
Query: 5581 AIYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVI 5760
AIYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVI
Sbjct: 1861 AIYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVI 1920
Query: 5761 LSNDQSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAEL 5940
LSNDQS KGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAEL
Sbjct: 1921 LSNDQSPTAVVTPVAIAVDADKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAEL 1980
Query: 5941 DHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAF 6120
DHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAF
Sbjct: 1981 DHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAF 2040
Query: 6121 DSIEVATINGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHINNGNCDHICIPLMF 6300
DSIEVATINGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHINNGNCDHICIPLMF
Sbjct: 2041 DSIEVATINGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHINNGNCDHICIPLMF 2100
Query: 6301 AQRTCTCANGYVKDGQTSCKLFDESFVIVATKTKVIGYPIDETQSKGVAMEPIGGLSITG 6480
AQRTCTCANGYVKDGQTSCKLFDESFVIVATKTKVIGYPIDETQSKGVAMEPIGGLSITG
Sbjct: 2101 AQRTCTCANGYVKDGQTSCKLFDESFVIVATKTKVIGYPIDETQSKGVAMEPIGGLSITG 2160
Query: 6481 VDYDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINYNMYFI 6660
VDYDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINYNMYFI
Sbjct: 2161 VDYDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINYNMYFI 2220
Query: 6661 NHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQRSFLDG 6840
NHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQRSFLDG
Sbjct: 2221 NHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQRSFLDG 2280
Query: 6841 SRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPELVRSDIASAAGVA 7020
SRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPELVRSDIASAAGVA
Sbjct: 2281 SRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPELVRSDIASAAGVA 2340
Query: 7021 LHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRASSPC 7200
LHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRASSPC
Sbjct: 2341 LHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRASSPC 2400
Query: 7201 QITDNLRKSPCTQLCFATPGTQTPTCSCARGVLKGRTCEEPDTYIMFSDGDKIIDVAIEP 7380
QITDNLRKSPCTQLCFATPGTQTPTCSCARGVLKGRTCEEPDTYIMFSDGDKIIDVAIEP
Sbjct: 2401 QITDNLRKSPCTQLCFATPGTQTPTCSCARGVLKGRTCEEPDTYIMFSDGDKIIDVAIEP 2460
Query: 7381 DVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAENPRLVFGAS 7560
DVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAENPRLVFGAS
Sbjct: 2461 DVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAENPRLVFGAS 2520
Query: 7561 KQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTIASGDWTYALAIDPC 7740
KQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTIASGDWTYALAIDPC
Sbjct: 2521 KQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTIASGDWTYALAIDPC 2580
Query: 7741 SGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVDFRNQKIYWADV 7920
SGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVDFRNQKIYWADV
Sbjct: 2581 SGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVDFRNQKIYWADV 2640
Query: 7921 NRLNIEVADYDGQNRKVIASGYRAKSLDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVS 8100
NRLNIEVADYDGQNRKVIASGYRAKSLDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVS
Sbjct: 2641 NRLNIEVADYDGQNRKVIASGYRAKSLDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVS 2700
Query: 8101 DRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLCTVVADDIGLAASKVQCS 8280
DRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLCTVVADDIGLAASKVQCS
Sbjct: 2701 DRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLCTVVADDIGLAASKVQCS 2760
Query: 8281 CNDTYELVQEPGKDYPTQCVLRGSNSEPAKECLPPYNFQCGDGSCILLGATCDSKPDCAD 8460
CNDTYELVQEPGKDYPTQCVLRGSNSEPAKECLPPYNFQCGDGSCILLGATCDSKPDCAD
Sbjct: 2761 CNDTYELVQEPGKDYPTQCVLRGSNSEPAKECLPPYNFQCGDGSCILLGATCDSKPDCAD 2820
Query: 8461 ASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHIDDCGDGSDELDCPSAVACAEGTFP 8640
ASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHIDDCGDGSDELDCPSAVACAEGTFP
Sbjct: 2821 ASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHIDDCGDGSDELDCPSAVACAEGTFP 2880
Query: 8641 CSNGHCINQTKVCDGHNDCHDEQVSDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCD 8820
CSNGHCINQTKVCDGHNDCHDEQVSDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCD
Sbjct: 2881 CSNGHCINQTKVCDGHNDCHDEQVSDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCD 2940
Query: 8821 GYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDT 9000
GYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDT
Sbjct: 2941 GYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDT 3000
Query: 9001 AGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNA 9180
AGKKICVGDYLFQCDNLKCISRAFI HSRHGCGNRTCTDQEFHCTSNA
Sbjct: 3001 AGKKICVGDYLFQCDNLKCISRAFICDGEDDCGDGSDEHSRHGCGNRTCTDQEFHCTSNA 3060
Query: 9181 KLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECNKGEFRCSNQHCIHSTWECD 9360
KLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECNKGEFRCSNQHCIHSTWECD
Sbjct: 3061 KLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECNKGEFRCSNQHCIHSTWECD 3120
Query: 9361 GDNDCLDGSDEHANCTYSSCQPDFFQCANHKCVPNSWKCDGNDDCEDGSDEKDCPKNSAS 9540
GDNDCLDGSDEHANCTYSSCQPDFFQCANHKCVPNSWKCDGNDDCEDGSDEKDCPKNSAS
Sbjct: 3121 GDNDCLDGSDEHANCTYSSCQPDFFQCANHKCVPNSWKCDGNDDCEDGSDEKDCPKNSAS 3180
Query: 9541 AQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCM 9720
AQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCM
Sbjct: 3181 AQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCM 3240
Query: 9721 DMKIGYKCDCFEGFAIDISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSS 9900
DMKIGYKCDCFEGFAIDISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSS
Sbjct: 3241 DMKIGYKCDCFEGFAIDISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSS 3300
Query: 9901 DDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLID 10080
DDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLID
Sbjct: 3301 DDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLID 3360
Query: 10081 QGKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELD 10260
QGKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELD
Sbjct: 3361 QGKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELD 3420
Query: 10261 GRFCKTLIRDRIQQPKAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHD 10440
GRFCKTLIRDRIQQPKAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHD
Sbjct: 3421 GRFCKTLIRDRIQQPKAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHD 3480
Query: 10441 LGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWA 10620
LGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWA
Sbjct: 3481 LGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWA 3540
Query: 10621 DWNLREVLRCDKWTGKNETILKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIG 10800
DWNLREVLRCDKWTGKNETILKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIG
Sbjct: 3541 DWNLREVLRCDKWTGKNETILKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIG 3600
Query: 10801 AGGNGYTCSCPDQFVLLSDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDE 10980
AGGNGYTCSCPDQFVLLSDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDE
Sbjct: 3601 AGGNGYTCSCPDQFVLLSDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDE 3660
Query: 10981 PGESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXXEQNCDKACDPWMFKCAATG 11160
PGESICGQRICPVGEFQCTNHNCTRPFQI EQNCDKACDPWMFKCAATG
Sbjct: 3661 PGESICGQRICPVGEFQCTNHNCTRPFQICDGNDDCGDSSDEQNCDKACDPWMFKCAATG 3720
Query: 11161 RCIPRRFTXXXXXXXXXRSDEADTLCMSAERNCTAEEFRCNNNKCIAKAWRXXXXXXXXX 11340
RCIPRRFT RSDEADTLCMSAERNCTAEEFRCNNNKCIAKAWR
Sbjct: 3721 RCIPRRFTCDGDDDCGDRSDEADTLCMSAERNCTAEEFRCNNNKCIAKAWRCDNDDDCGD 3780
Query: 11341 XXXETPECAQIECKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFR 11520
ETPECAQIECKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFR
Sbjct: 3781 GSDETPECAQIECKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFR 3840
Query: 11521 CATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGT 11700
CATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGT
Sbjct: 3841 CATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGT 3900
Query: 11701 IQCSDGLDESQCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCS 11880
IQCSDGLDESQCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCS
Sbjct: 3901 IQCSDGLDESQCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCS 3960
Query: 11881 PFEFECANSVCIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQL 12060
PFEFECANSVCIPRKFM SDETSSECRSAQCDPPLRFRCAHSRLCLNILQL
Sbjct: 3961 PFEFECANSVCIPRKFMCDGDNDCGDNSDETSSECRSAQCDPPLRFRCAHSRLCLNILQL 4020
Query: 12061 CNGFNDCGPNDFSDEHLSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDE 12240
CNGFNDCGPNDFSDEHLSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDE
Sbjct: 4021 CNGFNDCGPNDFSDEHLSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDE 4080
Query: 12241 IGCSKHGGKTSCEAFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNN 12420
IGCSKHGGKTSCEAFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNN
Sbjct: 4081 IGCSKHGGKTSCEAFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNN 4140
Query: 12421 TCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGS 12600
TCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGS
Sbjct: 4141 TCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGS 4200
Query: 12601 GTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDF 12780
GTNRH PRKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDF
Sbjct: 4201 GTNRHAAAKANDDDNDIIGIAFDPRKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDF 4260
Query: 12781 AAMGVVPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGR 12960
AAMGVVPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGR
Sbjct: 4261 AAMGVVPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGR 4320
Query: 12961 YLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSM 13140
YLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSM
Sbjct: 4321 YLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSM 4380
Query: 13141 AIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSRESKTL 13320
AIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSRESKTL
Sbjct: 4381 AIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSRESKTL 4440
Query: 13321 YVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTGFAC 13500
YVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTGFAC
Sbjct: 4441 YVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTGFAC 4500
Query: 13501 LCPDGIVPQLDGSCATQHVEALTMPKQCKCTNGGKCRLDGSCECTSDFEGDQCEKESSVS 13680
LCPDGIVPQLDGSCATQHVEALTMPKQCKCTNGGKCRLDGSCECTSDFEGDQCEKESSVS
Sbjct: 4501 LCPDGIVPQLDGSCATQHVEALTMPKQCKCTNGGKCRLDGSCECTSDFEGDQCEKESSVS 4560
Query: 13681 RKIIGTLSENFITVXXXXXXXXXXXXXXXXXXXNLYKRRQLLFKKNEAADGSVSFHGNVI 13860
RKIIGTLSENFITV NLYKRRQLLFKKNEAADGSVSFHGNVI
Sbjct: 4561 RKIIGTLSENFITVLLYILAFLFAFGLIGFCALNLYKRRQLLFKKNEAADGSVSFHGNVI 4620
Query: 13861 SFSNPVLENKQDAPGSEFNMQQMTSMHDDSTTFTNPVYELEDVDMSSPPPSNDQPSTSAS 14040
SFSNPVLENKQDAPGSEFNMQQMTSMHDDSTTFTNPVYELEDVDMSSPPPSNDQPSTSAS
Sbjct: 4621 SFSNPVLENKQDAPGSEFNMQQMTSMHDDSTTFTNPVYELEDVDMSSPPPSNDQPSTSAS 4680
Query: 14041 AMSPNRPSTSAASSFVPPTFDQDEIELKTADEIIVPKAEISKPPIPARPKKEKADPLRVD 14220
AMSPNRPSTSAASSFVPPTFDQDEIELKTADEIIVPKAEISKPPIPARPKKEKADPLRVD
Sbjct: 4681 AMSPNRPSTSAASSFVPPTFDQDEIELKTADEIIVPKAEISKPPIPARPKKEKADPLRVD 4740
Query: 14221 NPLYDPDSEVSDV 14259
NPLYDPDSEVSDV
Sbjct: 4741 NPLYDPDSEVSDV 4753
>gi|39582476|emb|CAE66567.1| Hypothetical protein CBG11882
[Caenorhabditis briggsae]
Length = 4759
Score = 9213 bits (23907), Expect = 0.0
Identities = 4318/4761 (90%), Positives = 4468/4761 (93%), Gaps = 8/4761 (0%)
Frame = +1
Query: 1 MILRLLIFTALAVTTANSSTRQQ-----STFHSIQVDSPPSVRSRIISASVNTASSVCNE 165
MILR LIFTALAVTTANSSTRQQ S FHSIQVDSPPSVRSRIISASVNTASSVCNE
Sbjct: 1 MILRFLIFTALAVTTANSSTRQQAAAASSAFHSIQVDSPPSVRSRIISASVNTASSVCNE 60
Query: 166 NDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAEYQR 345
NDFRC+DGKCIR EW PHPGCKSDQWQCDTYTWHSVSCIAEYQR
Sbjct: 61 NDFRCSDGKCIRAEWKCDGSGDCSDGEDEKDCPHPGCKSDQWQCDTYTWHSVSCIAEYQR 120
Query: 346 CDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSC 525
CDNITDCADGSDEKDCPASTVDCSS NVFMCADGRQCFD++KKCDGKYDCRDLSDEKDSC
Sbjct: 121 CDNITDCADGSDEKDCPASTVDCSSPNVFMCADGRQCFDITKKCDGKYDCRDLSDEKDSC 180
Query: 526 SRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRC 705
SRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEP+TCEFKKCTANEFQCKNKRC
Sbjct: 181 SRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPETCEFKKCTANEFQCKNKRC 240
Query: 706 QPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQ 885
QPRKFRCDYYDDCGDNSDE+ECGEYRCPPGKWNCPGTGHCI+QLKLCDGSKDCADGADEQ
Sbjct: 241 QPRKFRCDYYDDCGDNSDEEECGEYRCPPGKWNCPGTGHCIEQLKLCDGSKDCADGADEQ 300
Query: 886 QCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANH 1065
QCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANH
Sbjct: 301 QCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANH 360
Query: 1066 RPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDE 1245
RPGFTCSCLGDCFTLQM+HGPGKDNLTMRGYC+SNNADKMKLFVARREGLYRLNPKNPDE
Sbjct: 361 RPGFTCSCLGDCFTLQMDHGPGKDNLTMRGYCISNNADKMKLFVARREGLYRLNPKNPDE 420
Query: 1246 EVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRC 1425
EVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRC
Sbjct: 421 EVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRC 480
Query: 1426 LAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTNQLK 1605
LAVDWITNTLYIIESGSRRIDVSSYDG+RRTVLLADGLTLPLDIALDPLRGEMFFTNQLK
Sbjct: 481 LAVDWITNTLYIIESGSRRIDVSSYDGDRRTVLLADGLTLPLDIALDPLRGEMFFTNQLK 540
Query: 1606 LEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQG 1785
+EAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQG
Sbjct: 541 IEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQG 600
Query: 1786 MNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMA 1965
MN VPHPFGLALFDQYLYWTDWTRLGV+QVEKFGSDTKLLWSNTENNVFPMGISAYHPMA
Sbjct: 601 MNTVPHPFGLALFDQYLYWTDWTRLGVVQVEKFGSDTKLLWSNTENNVFPMGISAYHPMA 660
Query: 1966 QPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGKRCIDSI 2145
QPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGKRCIDSI
Sbjct: 661 QPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGKRCIDSI 720
Query: 2146 DYLLFSSNKIVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMD 2325
DYLLFSSNKIVRGIFPEI EKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMD
Sbjct: 721 DYLLFSSNKIVRGIFPEIAEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMD 780
Query: 2326 NTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPD 2505
NTIYRIRPDGEG+APVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLV PD
Sbjct: 781 NTIYRIRPDGEGSAPVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVQPD 840
Query: 2506 ELVRRQLITELRDPVSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSE 2685
ELVRRQL+TELRDPVSVVVHPWKGLLFYAEAMRPAAIY+CHIDG NCQVIRNTTLGRPSE
Sbjct: 841 ELVRRQLLTELRDPVSVVVHPWKGLLFYAEAMRPAAIYKCHIDGTNCQVIRNTTLGRPSE 900
Query: 2686 MAIDFAENRLCWGDTLLKTISCMDFDGKNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSI 2865
MAIDF E+R+CWGDTLLKTISCMD DGKNV LD D PIPVAITI+NEYIYYVHQRPYSI
Sbjct: 901 MAIDFEEDRICWGDTLLKTISCMDLDGKNVNTLDTDTPIPVAITILNEYIYYVHQRPYSI 960
Query: 2866 RRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPS 3045
RRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIP+DSREHPCRASQCTQLCFATPS
Sbjct: 961 RRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIPEDSREHPCRASQCTQLCFATPS 1020
Query: 3046 ESHPNELEAKCACRQGFMINKENNHSCQKDPAEKIEQLCSSNSTQFQCKNGRCIPKEWKC 3225
ES PN LEAKCACR+GF IN +NNHSCQ+D +E IE LC +NSTQF CKNGRCIPKEWKC
Sbjct: 1021 ESDPNTLEAKCACREGFKINADNNHSCQRDKSESIEVLCPNNSTQFLCKNGRCIPKEWKC 1080
Query: 3226 DGENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXV 3405
DGENDCLDESDE+DEKGDKCFHETECAENTIKCRNTKKCIPAQ V
Sbjct: 1081 DGENDCLDESDEVDEKGDKCFHETECAENTIKCRNTKKCIPAQYGCDGDNDCGDYSDEDV 1140
Query: 3406 KYCKDGQKPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNATCAANQFSCA 3585
KYCK+GQKPVC+AKKFQCDNHRCIPEQWK EK+E+CGNATCAANQFSCA
Sbjct: 1141 KYCKEGQKPVCSAKKFQCDNHRCIPEQWKCDSDNDCGDGSDEKIELCGNATCAANQFSCA 1200
Query: 3586 NGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQCVPLRNHXXXXXXXX 3765
NGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQCVPLRNH
Sbjct: 1201 NGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQCVPLRNHCDGQNDCE 1260
Query: 3766 XXXXXXXXAVTAESCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSS 3945
AV++E+CT DQF+CVSSGLCIPASWK SDEP+FGCT GR+C +
Sbjct: 1261 DGSDEDSCAVSSETCTSDQFQCVSSGLCIPASWKCDGQVDCDDESDEPRFGCTRGRECKA 1320
Query: 3946 DQFKCGNGRCILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIP 4125
DQFKCGNGRCILNNWLCDGENDCGDGSDES+ERGCK+ MN RKCPFEHV CEND ETCIP
Sbjct: 1321 DQFKCGNGRCILNNWLCDGENDCGDGSDESAERGCKSPMNTRKCPFEHVPCENDPETCIP 1380
Query: 4126 LHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCSFKCHNSPNGPICSCPFGEQLVNKTKC 4305
LHQLCDGK HCPGGTDEGGRC RDLCSADRAGC+FKCHNSPNGPICSCP GEQLVNKTKC
Sbjct: 1381 LHQLCDGKRHCPGGTDEGGRCGRDLCSADRAGCAFKCHNSPNGPICSCPQGEQLVNKTKC 1440
Query: 4306 EPENECLDSSSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIY 4485
EPENECLD+SSCSQ CKDEKHGFTCSC+EGYELD +KRTCKV DNVKDTRIYVSNRNRIY
Sbjct: 1441 EPENECLDASSCSQHCKDEKHGFTCSCEEGYELDANKRTCKVQDNVKDTRIYVSNRNRIY 1500
Query: 4486 YSDHKLDNWHTFGAIVENAIALAWDSLTDRIYWSDIREKKILSANRNGTNATVFIADGLD 4665
YSDHKLDNWHTFGA+VENAIALAWDSLTDRIYWSDIREKKILSANRNGTNATVFI+DGLD
Sbjct: 1501 YSDHKLDNWHTFGAVVENAIALAWDSLTDRIYWSDIREKKILSANRNGTNATVFISDGLD 1560
Query: 4666 ITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFW 4845
ITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQN+SQPRGIAVDPRKGVMFW
Sbjct: 1561 ITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNISQPRGIAVDPRKGVMFW 1620
Query: 4846 TDWGQNPCIERASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGS 5025
TDWGQNPCIERASMDG+DRQIIVKTKIYWPNTIALD TT+RVYFADSKLDFIDFVNYDG+
Sbjct: 1621 TDWGQNPCIERASMDGSDRQIIVKTKIYWPNTIALDLTTNRVYFADSKLDFIDFVNYDGT 1680
Query: 5026 GRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGV 5205
GRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTT EYPSHTFSKALGV
Sbjct: 1681 GRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTGEYPSHTFSKALGV 1740
Query: 5206 VAVHPVLQPVIKNNPCSTNPCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKPFLVI 5385
VAVHP LQPVIKNNPCS NPCSHLCLLNNKNTFTCKCPMGEKLD SGKKC+DDAKPFLVI
Sbjct: 1741 VAVHPALQPVIKNNPCSNNPCSHLCLLNNKNTFTCKCPMGEKLDGSGKKCVDDAKPFLVI 1800
Query: 5386 IQKTNVFGIEMNSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQ 5565
IQKTNVFG+EM+S S TP LAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQ
Sbjct: 1801 IQKTNVFGVEMDSRSPTGTPDLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQ 1860
Query: 5566 ITTDSAIYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQ 5745
ITTDSAIYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNK+TQTIE+IRTQGKQ
Sbjct: 1861 ITTDSAIYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKVTQTIELIRTQGKQ 1920
Query: 5746 YRSVILSNDQSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASN 5925
YRSVILSNDQS KGYVFWLDRGGGA+DAKVARAGLDGSNPLVIASN
Sbjct: 1921 YRSVILSNDQSPTAVVTPVSIAVDADKGYVFWLDRGGGASDAKVARAGLDGSNPLVIASN 1980
Query: 5926 DLAELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFY 6105
DLAELDHIA+DTTN RVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAF+GDRLFY
Sbjct: 1981 DLAELDHIALDTTNQRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFHGDRLFY 2040
Query: 6106 ADSAFDSIEVATINGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHINNGNCDHIC 6285
ADSAFDSIEVATI GDSQPP WTHFKKDVENLANIK LQPRASSS HPCHINNGNCDHIC
Sbjct: 2041 ADSAFDSIEVATILGDSQPPSWTHFKKDVENLANIKVLQPRASSSSHPCHINNGNCDHIC 2100
Query: 6286 IPLMFAQRTCTCANGYVKDGQTSCKLFDESFVIVATKTKVIGYPIDETQSKGVAMEPIGG 6465
IP MFAQ C+CANG+ KDGQTSCKLFDESFVIVATKTKV GYPIDE+QSKGVAMEPIGG
Sbjct: 2101 IPQMFAQHACSCANGFTKDGQTSCKLFDESFVIVATKTKVTGYPIDESQSKGVAMEPIGG 2160
Query: 6466 LSITGVDYDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINY 6645
LSITGVDYD+ESKTIYVAEASGINKGITAYTIGES+PRAVIRDSIGSLTIKSLAIDWINY
Sbjct: 2161 LSITGVDYDFESKTIYVAEASGINKGITAYTIGESAPRAVIRDSIGSLTIKSLAIDWINY 2220
Query: 6646 NMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQR 6825
NMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPV+RYLYWADQGQKP+IQR
Sbjct: 2221 NMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVARYLYWADQGQKPSIQR 2280
Query: 6826 SFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPELVRSDIAS 7005
+FLDGSRREVIVSSGI EPTDLVVDVAS+MIYWSDAK+DGI+RVRSTGGTPELVRSDIAS
Sbjct: 2281 AFLDGSRREVIVSSGIGEPTDLVVDVASRMIYWSDAKLDGIFRVRSTGGTPELVRSDIAS 2340
Query: 7006 AAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPR 7185
AAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSS NQPR
Sbjct: 2341 AAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSTNQPR 2400
Query: 7186 ASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCARGVLKGRTCEEPDTYIMFSDGDKIID 7365
ASSPCQITDNLRKSPCTQLCFATPGTQTP C+CARGVLKGRTCEEPDTY+MFSDGDKIID
Sbjct: 2401 ASSPCQITDNLRKSPCTQLCFATPGTQTPICACARGVLKGRTCEEPDTYLMFSDGDKIID 2460
Query: 7366 VAIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAENPRL 7545
AIEPDVKASRPLK+PFPEI+NLQTFDVDVNLRRVYFVVESP+GVNISWFSMNNAENPRL
Sbjct: 2461 AAIEPDVKASRPLKEPFPEITNLQTFDVDVNLRRVYFVVESPIGVNISWFSMNNAENPRL 2520
Query: 7546 VFGASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTIASGDWTYAL 7725
VFGASKQ HAKE+RHISDMKLDWLTQKIYFTTGRGGKVM ID AGEHLSTIASGDWTYAL
Sbjct: 2521 VFGASKQAHAKEVRHISDMKLDWLTQKIYFTTGRGGKVMVIDAAGEHLSTIASGDWTYAL 2580
Query: 7726 AIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVDFRNQKI 7905
AIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAI VDFRNQ I
Sbjct: 2581 AIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAITVDFRNQMI 2640
Query: 7906 YWADVNRLNIEVADYDGQNRKVIASGYRAKSLDIWDRWLYMSDPLSNGVFRIDKESGSGL 8085
YWADVNRLNIEVADY+G+NRK+IASGYRAKSLD+WDRWLYMSDPLSNGVFRIDKESGSGL
Sbjct: 2641 YWADVNRLNIEVADYNGENRKIIASGYRAKSLDLWDRWLYMSDPLSNGVFRIDKESGSGL 2700
Query: 8086 ENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLCTVVADDIGLAAS 8265
ENVVS+RRIPGALRVFASESDVRTRNQVCNALT+QLCK DNGGCDQLC+V+ADD+GLAAS
Sbjct: 2701 ENVVSNRRIPGALRVFASESDVRTRNQVCNALTTQLCKNDNGGCDQLCSVIADDVGLAAS 2760
Query: 8266 KVQCSCNDTYELVQEPGKDYPTQCVLRGSNSEPAKECLPPYNFQCGDGSCILLGATCDSK 8445
KVQCSCNDTYELVQEPGKDYPTQCVLRGS+SEPAKECLPPYNFQCGDGSCILLGATCDSK
Sbjct: 2761 KVQCSCNDTYELVQEPGKDYPTQCVLRGSSSEPAKECLPPYNFQCGDGSCILLGATCDSK 2820
Query: 8446 PDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHIDDCGDGSDELDCPSAVACA 8625
PDC DASDENPNYCNTR+CP+ Y+LCTNRRCIDSAKKCNHIDDCGDGSDELDCPSAV+CA
Sbjct: 2821 PDCPDASDENPNYCNTRACPDGYHLCTNRRCIDSAKKCNHIDDCGDGSDELDCPSAVSCA 2880
Query: 8626 EGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPGLPIDCRGVKVRCPNTNICIQP 8805
EGTFPCSNGHCINQTKVCDGHNDCHDEQVSDES ATCP LPIDCRGVK+RCPNTNICIQP
Sbjct: 2881 EGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESRATCPNLPIDCRGVKIRCPNTNICIQP 2940
Query: 8806 ADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHT 8985
ADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHT
Sbjct: 2941 ADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHT 3000
Query: 8986 NCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFH 9165
NCTDT+GKKICVGDYLFQCDNLKCISRAFI H+RHGCGNRTCTDQEFH
Sbjct: 3001 NCTDTSGKKICVGDYLFQCDNLKCISRAFICDGEDDCGDGSDEHARHGCGNRTCTDQEFH 3060
Query: 9166 CTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECNKGEFRCSNQHCIHS 9345
C SNAKLAQPKYECIPRAWLCDGDVTCAGGEDEST+LCKTEKKECNKGEFRC+NQHCIH+
Sbjct: 3061 CASNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTDLCKTEKKECNKGEFRCNNQHCIHA 3120
Query: 9346 TWECDGDNDCLDGSDEHANCTYSSCQPDFFQCANHKCVPNSWKCDGNDDCEDGSDEKDCP 9525
+WECDGDNDCLDGSDEHANCTYSSCQPDF+QCANHKCVPNSW+CDGNDDCEDGSDEKDCP
Sbjct: 3121 SWECDGDNDCLDGSDEHANCTYSSCQPDFWQCANHKCVPNSWRCDGNDDCEDGSDEKDCP 3180
Query: 9526 KNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLC 9705
KNSA+ QK SKCS QFQCTSGECIDDAKVCDRNFDC DRSDESSLCFIDECSLAEKPLC
Sbjct: 3181 KNSAAGQKTSKCSKSQFQCTSGECIDDAKVCDRNFDCGDRSDESSLCFIDECSLAEKPLC 3240
Query: 9706 EQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDG 9885
EQKC+D KIGYKCDCFEGFAID+SDQKSCHNVNEC+EGISGCSQKCDDKIGSYKC CVDG
Sbjct: 3241 EQKCIDQKIGYKCDCFEGFAIDVSDQKSCHNVNECFEGISGCSQKCDDKIGSYKCACVDG 3300
Query: 9886 YQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKK 10065
YQLSSDDHSCKR EMEPEPFFLLANKHYIRKIS+DGNKYELAAQGFDNVVSLDIDLTEKK
Sbjct: 3301 YQLSSDDHSCKRVEMEPEPFFLLANKHYIRKISMDGNKYELAAQGFDNVVSLDIDLTEKK 3360
Query: 10066 AYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIR 10245
AYLIDQGKLRLLRV+LDEMDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIR
Sbjct: 3361 AYLIDQGKLRLLRVNLDEMDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIR 3420
Query: 10246 VCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFK 10425
VCELDGRFCKTLIRDRIQQPKAI +HPGKGYLFFTEWSLQPYIGR+ALDGSPEL DPIFK
Sbjct: 3421 VCELDGRFCKTLIRDRIQQPKAIAIHPGKGYLFFTEWSLQPYIGRMALDGSPELPDPIFK 3480
Query: 10426 LAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVVFDD 10605
LAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMV+FDD
Sbjct: 3481 LAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVIFDD 3540
Query: 10606 YLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGCSH 10785
YLYWADWNLREV+RCDKWTGKNET+LKKTVQLPNDLRIVHPM+QPAYPNPCGDNNGGCSH
Sbjct: 3541 YLYWADWNLREVVRCDKWTGKNETVLKKTVQLPNDLRIVHPMKQPAYPNPCGDNNGGCSH 3600
Query: 10786 LCLIGAGGNGYTCSCPDQFVLLSDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCR 10965
LCLIGAGGNGYTCSCPDQFVLL DQKTCEPNCT+RQFACGGDDAKCIPKLWYCDGEPDCR
Sbjct: 3601 LCLIGAGGNGYTCSCPDQFVLLPDQKTCEPNCTDRQFACGGDDAKCIPKLWYCDGEPDCR 3660
Query: 10966 DGSDEPGESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXXEQNCDKACDPWMFK 11145
DGSDEPGESICGQRICPVGEFQCTNHNCTRPFQI EQNCDKACDPWMFK
Sbjct: 3661 DGSDEPGESICGQRICPVGEFQCTNHNCTRPFQICDGNDDCGDGTDEQNCDKACDPWMFK 3720
Query: 11146 CAATGRCIPRRFTXXXXXXXXXRSDEADTLCMSAERNCTAEEFRCNNNKCIAKAWRXXXX 11325
CAATGRCIP+RFT RSDEAD+LCMS +RNCTAEEFRCNNNKCIAKAWR
Sbjct: 3721 CAATGRCIPKRFTCDGDDDCGDRSDEADSLCMSPDRNCTAEEFRCNNNKCIAKAWRCDND 3780
Query: 11326 XXXXXXXXETPECAQIECKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDD 11505
ETPECAQIECKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDD
Sbjct: 3781 DDCGDGSDETPECAQIECKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDD 3840
Query: 11506 VGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSK 11685
VGEFRCAT+GKCIP+RWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSK
Sbjct: 3841 VGEFRCATTGKCIPKRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSK 3900
Query: 11686 VCDGTIQCSDGLDESQCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCEDVS 11865
VCDGTIQCSDGLDESQCTLRRC GHRQCDDGTCIAEHKWCDRKKDCPNAADELHCEDVS
Sbjct: 3901 VCDGTIQCSDGLDESQCTLRRCTAGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCEDVS 3960
Query: 11866 RRTCSPFEFECANSVCIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCL 12045
RRTCSPFEFECANSVCIPRKFM SDETS+ECR AQCDPPLRFRCAHSRLCL
Sbjct: 3961 RRTCSPFEFECANSVCIPRKFMCDGDNDCGDNSDETSTECRMAQCDPPLRFRCAHSRLCL 4020
Query: 12046 NILQLCNGFNDCGPNDFSDEHLSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCG 12225
NILQLCNG DCGPNDFSDEHLSMCSSFSE DC+SDQFKC+NGKCVN T+ACDRKDDCG
Sbjct: 4021 NILQLCNGMPDCGPNDFSDEHLSMCSSFSEGSDCASDQFKCSNGKCVNATLACDRKDDCG 4080
Query: 12226 DASDEIGCSKHGGKTSCEAFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDE 12405
DASDEIGCSKHGGKTSCEAFGNNGGCK ICTDVRDGFYCHCRDGFRPDPQSPKECIDIDE
Sbjct: 4081 DASDEIGCSKHGGKTSCEAFGNNGGCKQICTDVRDGFYCHCRDGFRPDPQSPKECIDIDE 4140
Query: 12406 CAGNNTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQL 12585
CAGNNTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGAD SLVQL
Sbjct: 4141 CAGNNTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADSSLVQL 4200
Query: 12586 SLHGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERTIYRSAIANGNQSHEGQK 12765
SLHG+GTNRH PRKELMYWIDGSERTIYRSAI+NGNQSHEGQK
Sbjct: 4201 SLHGTGTNRHAAAKANDEDSDIIGIAFDPRKELMYWIDGSERTIYRSAISNGNQSHEGQK 4260
Query: 12766 LDVDFAAMGVVPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVC 12945
LD+DFA MGVVPTAIAVDYTTGNLF+AAVSE++ENGLVTARKKRMSEPIDNQNTGFIF+
Sbjct: 4261 LDIDFAGMGVVPTAIAVDYTTGNLFVAAVSEDVENGLVTARKKRMSEPIDNQNTGFIFLA 4320
Query: 12946 LPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVF 13125
LPDGRY+KKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVF
Sbjct: 4321 LPDGRYVKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVF 4380
Query: 13126 SPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSR 13305
SPTSMAIDEGK NRIYWVDPKYRRVDAVNIDG++RTTVVHD+HIPYAVDVFENHIYWLSR
Sbjct: 4381 SPTSMAIDEGKNNRIYWVDPKYRRVDAVNIDGTDRTTVVHDKHIPYAVDVFENHIYWLSR 4440
Query: 13306 ESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPS 13485
ESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQR VSGCERAQCSHLCV+LPS
Sbjct: 4441 ESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRVVSGCERAQCSHLCVTLPS 4500
Query: 13486 TGFACLCPDGIVPQLDGSCATQHVEALTMPKQCKCTNGGKCRLDGSCECTSDFEGDQCEK 13665
+GFACLCP+GIVPQ+DGSCATQHVEALTMPKQCKCTNGGKCRLDGSCECTSDFEGD C+K
Sbjct: 4501 SGFACLCPEGIVPQMDGSCATQHVEALTMPKQCKCTNGGKCRLDGSCECTSDFEGDLCDK 4560
Query: 13666 ESSVSRKIIGTLSENFITVXXXXXXXXXXXXXXXXXXXNLYKRRQLLFKKNEAADGSVSF 13845
ESSVSR+IIGTLSENF TV N+YKRRQLLFKKNEAADGSVSF
Sbjct: 4561 ESSVSRRIIGTLSENFFTVLLYILAFLAAFGLIGFIGLNVYKRRQLLFKKNEAADGSVSF 4620
Query: 13846 HGNVISFSNPVLENKQDAPGSEFNMQQMTSMHDDSTTFTNPVYELEDVDMSSPPPSNDQP 14025
HGNVISFSNPVLE+KQDAPGSEF+MQQMTSMHDDSTTFTNPVY+LEDVDMSS P S+++P
Sbjct: 4621 HGNVISFSNPVLESKQDAPGSEFSMQQMTSMHDDSTTFTNPVYDLEDVDMSS-PRSDNRP 4679
Query: 14026 STSASAMSPNRPST-SAASSFVPPTFDQDEIELKTADEIIVPKAEISKPPIPARP--KKE 14196
STS SAMSPN PST SA+SSFVPPTF+QDEIE+KT+D++IVPK EISKPPIPARP K++
Sbjct: 4680 STS-SAMSPNGPSTSSASSSFVPPTFNQDEIEVKTSDQVIVPKVEISKPPIPARPNKKEK 4738
Query: 14197 KADPLRVDNPLYDPDSEVSDV 14259
K + LRVDNPLYDPDSEVSDV
Sbjct: 4739 KEETLRVDNPLYDPDSEVSDV 4759
>gi|31203671|ref|XP_310784.1| ENSANGP00000014849 [Anopheles gambiae]
gi|30177963|gb|EAA06237.2| ENSANGP00000014849 [Anopheles gambiae str.
PEST]
Length = 4569
Score = 2868 bits (7434), Expect = 0.0
Identities = 1677/4681 (35%), Positives = 2437/4681 (51%), Gaps = 133/4681 (2%)
Frame = +1
Query: 385 KDCPASTVDCSSQNVFMCADGRQ---CFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQY 555
+ C + C + ++ + +GR C K+CDG DCR DE + C TAC
Sbjct: 31 RKCQTDDIRCGAPSLGVSLNGRVAEICVPKEKRCDGYLDCRTGKDE-EGCPG--TACRLD 87
Query: 556 QFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYY 735
QFRCA+ +CI + C+ DC D SDE C F C +F+C N C P F CD Y
Sbjct: 88 QFRCANGVRCIDTALKCNHKNDCGDNSDEVG-CNFPPCHGGQFRCANALCIPATFHCDGY 146
Query: 736 DDCGDNSDEDECGEYRCPPGKWNCP-----GTGHCIDQLKLCDGSKDCADGADEQQ-CSQ 897
DC D SDE C CP K+ CP G CI + KLCDG +DC DG DE+ CS
Sbjct: 147 HDCSDESDEANCTAIACPDNKFLCPRGGPNGQAKCIVKSKLCDGKRDCDDGTDEETACST 206
Query: 898 NLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGF 1077
CP+LGC+ C PS GG C CP+G L +RTC+D++EC +G+CDQLC N F
Sbjct: 207 TSCPALGCEHKCGPSLTGGVCYCPAGRTLSPD-NRTCADLDECTVWGHCDQLCTNTDGSF 265
Query: 1078 TCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKK 1257
+C+C +TL ME + CV+ A ++LF A + R++ D +
Sbjct: 266 SCACATG-YTL-ME----------KTRCVAPTASSLELFFAYDRAILRMSAHGQDSRIIA 313
Query: 1258 LASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVD 1437
A+G G+ + Y ++W+D S + D G +L P +A+D
Sbjct: 314 NATGAS--GLSYHYAKNLLYWSDIKTRKVQSQVLVDGGFGGH--DFTLPGTWAPVAIAID 369
Query: 1438 WITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTNQLKLEAA 1617
W+ + LY+ + +++DV DG V+L LT P D+ALDP G MF + + A
Sbjct: 370 WVGDKLYVADLVGQKVDVFELDGRWHAVVLGSNLTSPADLALDPTAGLMFVADGSHVLRA 429
Query: 1618 AMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVV 1797
MDGT+ +++V+ ++ SG+ VD+ A+RV+W D +D +ES+ Y+G R ++ +G V
Sbjct: 430 HMDGTHAKSIVSEAAYKASGVAVDVIARRVFWCDSLLDYIESVSYEGERRVMILRGQQ-V 488
Query: 1798 PHPFGLALFDQYLYWTDWTRLGVIQVEKF-GSDTKLLWSNTENNVFPMGISAYHPMAQPG 1974
P P LALF+ ++W+D T+ G++ V++F GS + ++ P + A HP+ QP
Sbjct: 489 PSPSRLALFENRVFWSDATKQGIMSVDRFEGSSSIQSIFKAKDIREPRALIAVHPLTQP- 547
Query: 1975 PGQSECLAMKIENPC--TNADCEGMCILSKDNGG-FGVGYKCACPIGQKLVNG-KRCIDS 2142
K+ NPC N C MC+++ G G+GY+CAC G +L C
Sbjct: 548 ---------KVSNPCGSNNGGCSQMCVVTAVQGAPSGLGYRCACHTGWQLSKDLMNCHLV 598
Query: 2143 IDYLLFSSNKIVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIM 2322
+L++S + ++G + + ++A+LP+ R +G+ F+ D H +Y+D++
Sbjct: 599 RQFLMYSQQRFIKGKVLDPVIEGFSDAILPVVSRRARFVGLDFDA-VDEH---IYYSDVL 654
Query: 2323 DNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHP 2502
+ IYR+ +G G VL + N+G+ ++ DW+SK LYY+D+ + +L V+ T
Sbjct: 655 QDVIYRVHRNGTGREIVLASQNEGVEGLAVDWVSKNLYYIDSRKGTLNVLSTRNTS---- 710
Query: 2503 DELVRRQLITELRDPVSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPS 2682
RR L+ L+ P ++VVHP +G ++++E RPA I R + DG V RN TLG P+
Sbjct: 711 ---YRRTLLKNLKRPRAIVVHPNRGYIYFSEWDRPANISRANADGSGLIVFRNLTLGWPN 767
Query: 2683 EMAIDFAENRLCWGDTLLKTISCMDFDGKNVVKLDIDNPI---PVAITIMNEYIYYVHQR 2853
++IDF E+R+ W D LL + + DG +V +++ + P +I I E++Y R
Sbjct: 768 GLSIDFREDRVYWCDALLDHVQHANLDGTDV--RTVNSRLIRHPFSIVIHEEWMYITDWR 825
Query: 2854 PYSIRRVHKKNGGGSKI-VREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQ--CTQ 3024
+I R++K NG +I VRE ++ +K SH Q I PC + C +
Sbjct: 826 LDAIVRLNKLNGEQEEIMVRE--PQTNRLYGVKVYSHGVQSI---DASQPCGVNNGGCEK 880
Query: 3025 LCFATPSESHPN------------ELEAKCACRQGFMINKENNHSCQKDP-AEKIEQLCS 3165
LCFA P + L KC C G + ++ SC DP AE Q C
Sbjct: 881 LCFALPRNDTEDAAAASAGGPTSPRLVVKCGCPYGERLG-DDGRSCLSDPNAEPPVQAC- 938
Query: 3166 SNSTQFQCKNGRCIPKEWKCDGENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKKCI 3345
N+ F C N RCIPK W CDG++DCLD SDE C T C N +C+ + +CI
Sbjct: 939 PNTWDFTCNNQRCIPKSWICDGDDDCLDNSDE----EQNCTKPT-CGTNEFQCK-SGRCI 992
Query: 3346 PAQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXX 3525
P + CAA +F C+N RCIP WK
Sbjct: 993 PLNFRCDQENDCGDHSDEF-----ECGNVTCAASQFACENGRCIPNIWKCDSENDCGDGS 1047
Query: 3526 XEKLEMCGNATCAANQFSC-ANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFR 3702
E C TCA QF+C G CIP W+CDGD+DC+D +D++ CPP+ C A QF+
Sbjct: 1048 DEG-PFCAEKTCAYFQFTCPRTGHCIPQSWVCDGDDDCFD--KQDEKDCPPITCLANQFK 1104
Query: 3703 CANGRQCV--PLRNHXXXXXXXXXXXXXXXXAVTAESCTPDQFKCVSSGLCIPASWKXXX 3876
CA+ RQCV P + + F+C SSG+CIP +W
Sbjct: 1105 CADLRQCVEEPYKCDGIPDCNDGSDELGCPTMEPNQCNLEKHFRCRSSGVCIPIAWHCDG 1164
Query: 3877 XXXXXXXSDEPKFGCTSGRQCSSDQFKCGNGRCILNNWLCDGENDCGDGSDESSERGCKT 4056
SDE S C + +KC N +C+ ++CDG++DCGDGSDES E C T
Sbjct: 1165 SNDCDDHSDEED---CSKITCPNGFYKCANAKCVFKAYICDGKDDCGDGSDESVEHACVT 1221
Query: 4057 SMNARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCSFKC 4236
++C AC E C+ L +CD CP G DEG C C CS C
Sbjct: 1222 P--PQRCAHGQWACPGVTERCVNLTSVCDDVPDCPNGADEGLGCDLAQCQHQTGLCSNGC 1279
Query: 4237 HNSPNGPICSCPFGEQLV-NKTKCEPENECLDSSSCSQRCKDEKHGFTCSCDEGYELDVD 4413
+P G +C CP GE+L + C+ NEC CSQRC + K + CSC +GY L+ +
Sbjct: 1280 QKTPLGALCICPPGEELAPDNFTCKDLNECDPPGLCSQRCTNTKGSYFCSCVDGYVLEPN 1339
Query: 4414 KRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGAIVENAIALAWDSLTDRIYWSDI 4593
K TCK A N + +SNR+ I +D K IVEN +A A + T I+WSD+
Sbjct: 1340 KHTCK-AVNHPAAFLIISNRHSILVADLKEQGLERVPIIVENVVATASNMHTGTIFWSDM 1398
Query: 4594 REKKILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRT 4773
+ KKI +R G I+ GLD+ EG+A DW+G+NLYW+DS LNTIEVA+ E+ R
Sbjct: 1399 KLKKISRLDR-GMEPQEIISTGLDLVEGLAYDWIGQNLYWLDSKLNTIEVAH-ENGSNRL 1456
Query: 4774 LLVHQNVSQPRGIAVDPRKGV--MFWTDWGQNPCIERASMDGTDRQIIVKTKIYWPNTIA 4947
+LV +N++QPRG+ +DP +FWTDWG+NP IER MDGT R+ IV TKIYWPN +
Sbjct: 1457 VLVRENITQPRGMCLDPSPTAKWLFWTDWGENPRIERIGMDGTMRETIVSTKIYWPNGLT 1516
Query: 4948 LDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQK 5127
LD T RVYFADSKLDFIDF Y+G+GR QVLA+S ++ H H+L++FED +Y++DR+L +
Sbjct: 1517 LDVATQRVYFADSKLDFIDFCYYNGTGRQQVLAASHYLLHAHSLSLFEDTLYWTDRQLNR 1576
Query: 5128 LQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTNPCSHLCLLNNKNT-- 5301
+ KY GT SH S+ L V HP LQP+ + +PC C H+CLL+
Sbjct: 1577 VLSAHKY-RGTNQTVVSHLISQPLSVHVHHPSLQPMYE-SPCKRAACQHVCLLSPSEPAG 1634
Query: 5302 FTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNVFGIEMNSASEKETPVLAGMVPLSGLG 5481
+ CKC G +L G +C ++ F+++++ + + N + +G++P+ G+
Sbjct: 1635 YACKCRPGYRLLPEG-RCTEEENAFIMLLKGNQIVDVPFNGGDARS----SGLMPVVGIE 1689
Query: 5482 NAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNGGNKTKMF--SSAVPDDAY 5655
YD E ++ ++ + + + IY + GGN+T+ + + AY
Sbjct: 1690 GGISLDYDRKGEMVYWVQGRDESD-----DENCTIYATPYGGGNRTEFLGPDTGLVGAAY 1744
Query: 5656 CLGFDWNGRNLVVGNKITQTIEIIRTQGK-QYRSVILSNDQSXXXXXXXXXXXXXXXKGY 5832
+ FDW GRNL VGN++ IE I GK +YR+V+L+ND + G
Sbjct: 1745 TIAFDWIGRNLYVGNRLASNIEAISVDGKVRYRTVVLANDGNRTSVAKPKQLALDPADGR 1804
Query: 5833 VFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAEL-DHIAIDTTNTRVYFSEAKAGRIS 6009
+FW+D GG KVA AG+DGS+P V+ +D + + I +D RVY+S +
Sbjct: 1805 LFWIDEGGFGVLTKVASAGMDGSDPRVL--DDTVQFPESITVDAEKRRVYYSTRLPPAVL 1862
Query: 6010 SVTYDGQDRHYVLSDGG--RQPNGLAFYGDRLFYADSAFDSI-EVATINGDSQPPQWTHF 6180
S+ YDG + +LS+ +P LA RL++ D ++ + V NGD+
Sbjct: 1863 SIEYDGTGQRTILSEENAISKPRALAVLESRLYFLDPTYEKLARVDLPNGDNA------- 1915
Query: 6181 KKDVENLANIK--ALQPRASSSGHPCHINNGNCDHICIPLMFAQRTCTCANGYVKDGQTS 6354
K ++N +++ + + SS HPC NNG C+H+C+P A R C C GY K+ + +
Sbjct: 1916 KLILDNEPDLRQMVIYRKRSSLQHPCTQNNGGCEHLCLPHAGASRVCACGVGYKKENEVA 1975
Query: 6355 CKLFDESFVIVATKTKVIGYPI-DETQSKGVAMEPIGGLS--ITGVDYDYESKTIYVAEA 6525
C + ++F +V+ G+ + D T+ AM PI G I VD Y IY E
Sbjct: 1976 CTPY-KTFAVVSQLDVTRGFSLRDSTE----AMVPIAGPGHHILHVDVLYRESWIYWVEY 2030
Query: 6526 S-GINKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINYNMYFINHDAERTNIEVSKL 6702
+ G GI + + +++D IGS I+ +AIDW+ N+YF N +EV+ L
Sbjct: 2031 NRGHWNGIFRVRPNGTELQHIVKDGIGSNGIRGIAIDWVAGNLYFTNVFPHENYVEVAWL 2090
Query: 6703 DGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQRSFLDGSRREVIVSSGIAEP 6882
DGT+RK+L+ T + P +AV+P+ R LYW D GQ P I + FLDGS +V+SGI+ P
Sbjct: 2091 DGTHRKVLVKTTNDAPRELAVNPIKRLLYWIDYGQYPRIGKCFLDGSNWTPVVTSGISNP 2150
Query: 6883 TDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPELVRSDIASAAGVALHGQNMYWTDNRLE 7062
DL VD+ + +YW D+K+D I +V +GG +++R ++A+ +A+ ++YW D L
Sbjct: 2151 RDLTVDMLTHDVYWVDSKLDMIQKVSYSGGHRQVIRRNLANPMALAVFLTDVYWVDRNLA 2210
Query: 7063 KLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPR-ASSPCQITDNLRKSPCTQ 7239
+FRA+ P ++ P + +L + D+ ++ N+QP ++PC L C Q
Sbjct: 2211 SVFRASKFPGNST---RPERLRTNLPKLRDITIYDINSQPMDDANPCL---RLGNGGCDQ 2264
Query: 7240 LCFATPG--TQTPT--CSCARGVL--KGRTCEEPDTYIMFSDGDKIIDVAIEPDVKASRP 7401
LCFA P +Q P+ C CA G L GR CE D YI+F+ +I + ++P + P
Sbjct: 2265 LCFALPPDYSQKPSFRCDCAVGRLGADGRHCELTDEYIIFATRTEIRAIDLDP-ASTNVP 2323
Query: 7402 LKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAENPRLVFGASKQPHAKE 7581
P ++N+ D D +++F P I+W + + A+ P
Sbjct: 2324 FA-PVANLTNVVGLDFDYADNKLFFTQIRPWS-KIAWLRGDKPD------AAAITPVMTR 2375
Query: 7582 IRHISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTIASGDWTYALAIDPCSGLLFWS 7761
+ + DW +KIY+T + A++T G L IA + A+ +DPC+G L+++
Sbjct: 2376 GINPEGIAYDWTQRKIYWTDSSNNSIYAMNTDGTELVMIARVERPRAIVLDPCNGTLYFT 2435
Query: 7762 DSG-YKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVDFRNQKIYWADVNRLNIE 7938
D G + TSG +I R+ +AG ++ I+ +S P+ +A+D+ ++ +YW D R IE
Sbjct: 2436 DWGRFGTSG-----KIFRTTMAGSLKRAIIDRDLSQPSGLAIDYDDRMLYWTDAVREKIE 2490
Query: 7939 VADYDGQNRKVIASG-YRAKSLDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVSDRRIP 8115
+ DG+NR+V+ S ++ ++ ++Y +D GV+R +K +G+G+ +V
Sbjct: 2491 RSQLDGRNREVLISATIYPFAITVFRNYIYWTDLQLRGVYRAEKHTGAGVHEMVK----- 2545
Query: 8116 GALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLCTVVADDIGLAASKVQCSCNDTY 8295
R+ S D+ + + C +NGGC Q C A+ K +C C+DT
Sbjct: 2546 ---RLEDSPRDIHIYSATRQQCQANPCLQNNGGCAQSCHPGAN------GKPECKCDDTT 2596
Query: 8296 ELVQEPGKDYPTQCVLRGSNSEPAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDEN 8475
+ V E G P F C +G CI +CD DC D SDE+
Sbjct: 2597 KPVNE------------GRMCAPKNHTCDASKFYCQNGKCISRMWSCDGDDDCGDGSDED 2644
Query: 8476 PNYCNTRSCPEDYNLCTNRRCIDSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCSNGH 8655
NYC SC + C N RCI + KC+H +DC DGSDE C S C +G F C+NG
Sbjct: 2645 VNYCAFHSCAANEFRCANGRCIFKSWKCDHENDCKDGSDEEGC-SYPPCVDGEFTCANGR 2703
Query: 8656 CINQTKVCDGHNDCHDEQVSDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDC 8835
CI Q +VC+G NDC D SDE+ CP C ++C TNIC++P LCDG +DC
Sbjct: 2704 CIPQAQVCNGVNDCKDNGTSDETHERCP-TNTTCPPNHLKCDRTNICVEPYWLCDGDNDC 2762
Query: 8836 GDKADENQLFCMNQQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKI 9015
GD +DEN L C + C Q+ RCP+ RCIP TW CDGD+DC DG DE C +
Sbjct: 2763 GDNSDENPLHCAQRTCPQNSFRCPNHRCIPATWYCDGDDDCGDGADEPPEYCKSEG--RT 2820
Query: 9016 CVGDYLFQCDNLKCISRAFIXXXXXXXXXXXXXHSRHGCGNRTC-TDQEFHCTSNAKLAQ 9192
C GD LF CDN CI R +I +RH C +R C D EF C N A
Sbjct: 2821 CFGD-LFTCDNGNCIPRIYICDGDNDCLDNSDEDNRHQCNDRKCDEDTEFTCHENK--AW 2877
Query: 9193 PKYECIPRAWLCDGDVTCAGGEDESTEL--CKTEKKECNKGEFRCSNQHCIHSTWECDGD 9366
+ +CIP+ W+CDGD C G DE+T L C + + C + F C+N CI+ W CD D
Sbjct: 2878 ARAQCIPKKWICDGDPDCVDGADENTTLQHCPS-PQPCGEDMFTCANGRCINQGWVCDHD 2936
Query: 9367 NDCLDGSDEHANCT--YSSCQPDFFQCANHKCVPNSWKCDGNDDCEDGSDEKDCPKNSAS 9540
NDC DGSDE NC Y +C P F C N KC+ N ++CDG DDC D SDE C K++A+
Sbjct: 2937 NDCGDGSDEGKNCNSQYKTCTPQEFTCQNFKCIRNQYRCDGEDDCGDHSDEVGCKKDNAT 2996
Query: 9541 AQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCM 9720
C+ G+F C +G+CID VC++ DCTD SDE C +DEC+ E C KC+
Sbjct: 2997 ------CAEGKFTCNNGQCIDYHLVCNKVPDCTDESDEPLHCNVDECAKVEIHRCGHKCV 3050
Query: 9721 DMKIGYKCDCFEGFAIDISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDG-YQLS 9897
D Y CDC +G+ + + D K+C +++EC E CSQ C + G Y C C + Y+
Sbjct: 3051 DTLTSYYCDCNQGYKL-LEDGKACADIDECIETPGVCSQHCSNTPGGYYCKCDERYYERQ 3109
Query: 9898 SDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLI 10077
+D+H+CKR + + +P+ + +NK+Y+R +S DG++Y L Q NVV++D D+ + + Y
Sbjct: 3110 NDEHTCKRKD-DTKPWLIFSNKYYVRNMSTDGHQYNLIHQDLMNVVAIDFDMQQHEMYFC 3168
Query: 10078 DQGKLRLLRVDLDEM--DSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVC 10251
D + + + D V++H+ +G EGIA+DWVGRKLY L+R +++ V
Sbjct: 3169 DVTAKTIFKSSFGSLVEDGVRIEKTPVIKHDSHGLEGIAIDWVGRKLYWLDRHSKNLDVA 3228
Query: 10252 ELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLA 10431
ELDG KTL R + P+AIVVHPG GYL+FT W LQ YI ++ +DGS +
Sbjct: 3229 ELDGTRRKTL-RSGVVDPRAIVVHPGIGYLYFTSWHLQAYIAKMGMDGSNFTR---ILTW 3284
Query: 10432 EHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHI--PAQRTSHVSSMVVFDD 10605
E D+ WPNA+ IDYF+DR++W DAHL+ I F D +G RH+ R HV ++ +FDD
Sbjct: 3285 EDDIAWPNALTIDYFTDRIYWADAHLDYIAFADLEGR-HRHVVLSGARVPHVFALSIFDD 3343
Query: 10606 YLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGCSH 10785
LYW DWNL+ +LR +K+TG N T+++ T P D+ I HP+RQ +PNPCG NGGCSH
Sbjct: 3344 SLYWTDWNLKAILRANKFTGANYTVVRNTTHRPYDVHISHPLRQIPFPNPCGTTNGGCSH 3403
Query: 10786 LCLIG---------------AGGNGYTCSCPDQFVLLSDQKTCEPNCTERQFACGGDDAK 10920
LCL+ G Y C+CP+QF L DQKTC NCT Q CGGDD K
Sbjct: 3404 LCLLAPPLESTYLNVEGYLEEGAPSYRCACPNQFYLARDQKTCIANCTSGQHRCGGDDEK 3463
Query: 10921 CIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXX 11100
CIP W CDGEPDC+D SDEP C R C G FQC N NCT I
Sbjct: 3464 CIPWFWKCDGEPDCKDRSDEPAS--CPARHCRAGTFQCGNGNCTPSTTICDGTDDCGDGT 3521
Query: 11101 XEQNCDKACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEADTLCMSAERNCTAE-EFR 11277
EQNCD C FKC ++GRCI + SDE +C +R C E EF
Sbjct: 3522 DEQNCDLPCPVSDFKCKSSGRCILDSWKCDGDADCKDGSDEDPEIC--HKRTCDPETEFS 3579
Query: 11278 CNNNKCIAKAWRXXXXXXXXXXXXETP-ECAQIECKKGWTRC--SSSYRCIPNWAFCNGQ 11448
C N +CI K W E C Q C GW+RC S+YRCIP W FC+G+
Sbjct: 3580 CKNGRCIPKLWMCDFDNDCGDDSDEPAYMCRQRNCTTGWSRCPGQSNYRCIPKWLFCDGK 3639
Query: 11449 DDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTR 11628
DDCRD SDE + CP C+ +F+C + +CIPR+WMCD +DCGD SDE + C G R
Sbjct: 3640 DDCRDKSDELPENCPQCNQETDFKC-NNNRCIPRQWMCDFADDCGDGSDESETQCKGKYR 3698
Query: 11629 PCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQCDDGTCIAEHKWC 11808
CSESEFRC++GKCI CD C D DE C +C G QC G CIA + C
Sbjct: 3699 ECSESEFRCDNGKCISSRWRCDHEDDCGDNSDEYGCEGFQCKNGTFQCKSGHCIAAYFRC 3758
Query: 11809 DRKKDCPNAADELHCED--VSRRTCSPFEFECANSVCIPRKFMXXXXXXXXXXSDETSSE 11982
D +DC + +DE+ C R C F+CAN++C+ + SDE +S
Sbjct: 3759 DGDRDCRDMSDEIGCPPRFPGGRYCPESRFQCANNLCVLPSDLCDGTDDCGDNSDEAASV 3818
Query: 11983 CRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDE-HLSMCSSFSEYGDCSSDQ 12159
C + CD RF+CA+ R C+ Q+C+G ++CG D SDE ++++C++ + D + Q
Sbjct: 3819 CTNFNCDTLRRFQCANHR-CVARYQICDGVDNCG--DGSDENNMTLCAARQKPCDLYT-Q 3874
Query: 12160 FKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKHICTDVRDGFY 12339
++CAN KC++ CD DDCGD SDE+GC + SC A N GGC+H C ++ DG+
Sbjct: 3875 YQCANKKCIDRAQVCDYADDCGDGSDELGCHR---TASCSAL-NKGGCEHHCVNLTDGYI 3930
Query: 12340 CHCRDGFRPDPQSPKECIDIDECA-GNNTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTG 12516
C C GF D + K C DIDECA G + C+ LC N G+Y C C E + + V +
Sbjct: 3931 CACYAGFIIDASNKKRCTDIDECATGTHGCSHLCTNLNGTYECGCREGFRLSDRVSGV-- 3988
Query: 12517 KDCRA-KGDAANVMIGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYW 12693
C+A KG+ V+ G ++ + NR P ++++W
Sbjct: 3989 --CKALKGEPLLVLSGGP----EIRAYEPAQNRQ--FDVIAGEKRIEALDYNPESQMIFW 4040
Query: 12694 IDGSERTIYRSAIAN--GNQSHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAVSENIE 12867
D ++TI RS + N + G D++ G PTA+AVD+ NL+ A
Sbjct: 4041 TDSYDKTIKRSYMVNAMNGDAKVGYAQDLNMKG-GTKPTALAVDWVADNLYWAETDR--- 4096
Query: 12868 NGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSD 13047
T K R G I V DGRY + +V L+ PTA+ P GR+ ++D
Sbjct: 4097 ----TGSKPR----------GRIMVAKTDGRYRRALVQAGLEVPTAIAVDPQLGRMFWAD 4142
Query: 13048 AGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSE 13227
AG KIE + MDG+ R+ I+ + + P + +D + + +YWVD K ++ + DG+
Sbjct: 4143 AGSAPKIEVSWMDGSKRRPIITEAIRHPAGLTVDYSQDHAVYWVDTKLNTIEVMKPDGTM 4202
Query: 13228 RTTVVHD---RHIPYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRV 13398
R TV+ +H P ++DVFE+ +YW++R++ L QDKFGRG + +L + +++V
Sbjct: 4203 RRTVLKGDLLKH-PVSLDVFESSLYWVTRDTGELLRQDKFGRGVQVTVQRNLANPSSIKV 4261
Query: 13399 SQKYAKDTQRTVSGCERAQCSHLCVSLPSTGFACLCPDGIVPQLDGSCATQHVEA----- 13563
+ +T + C R CSHLC+ +P G C CPD VP S A +A
Sbjct: 4262 YHELRYNTTLN-NPCYRNPCSHLCLLVPG-GRRCSCPDNTVPTSHRSTAEVVCDAPAERP 4319
Query: 13564 LTMPKQCKCTNGGKCRLDGS----------CECTSDFEGDQCEKESSVSRKIIGTLSENF 13713
P+ C C NGG C+ + C C +F G CE S KI+G +
Sbjct: 4320 RPAPRVCPCQNGGLCKEADAGPGAPSSELVCVCLPEFSGTHCE---VYSEKILGAAGSST 4376
Query: 13714 ITVXXXXXXXXXXXXXXXXXXXNLYKRRQLLFKKNEAADGSVSFH-GNVISFSNPVLENK 13890
+ + +++ K + ++ SVSF G + F++ +
Sbjct: 4377 TAIFVPLLILMLIIIAIGLF---VIVKKRTFGKPSLSSSQSVSFRPGTNVEFNSSEFPSA 4433
Query: 13891 QDAPG---------------SEFNMQQMTSMHDDSTTFTNPVYELEDVDMSSPPPSNDQP 14025
Q PG + + + ++++ +T F+NP+Y+ S P P+++ P
Sbjct: 4434 QRLPGVPGGAATGTTAGTAVTPLDGYSLDTLNNKNTDFSNPMYDAVQAG-SDPMPTSNMP 4492
Query: 14026 S 14028
S
Sbjct: 4493 S 4493
Score = 355 bits (910), Expect = 2e-95
Identities = 291/1074 (27%), Positives = 448/1074 (41%), Gaps = 78/1074 (7%)
Frame = +1
Query: 139 NTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHS 318
N C N+F+C G+CI + + C + Q+ C+ +
Sbjct: 973 NCTKPTCGTNEFQCKSGRCIPLNFRCDQENDCGDHSDEFECGNVTCAASQFACE-----N 1027
Query: 319 VSCIAEYQRCDNITDCADGS---------------------------------------- 378
CI +CD+ DC DGS
Sbjct: 1028 GRCIPNIWKCDSENDCGDGSDEGPFCAEKTCAYFQFTCPRTGHCIPQSWVCDGDDDCFDK 1087
Query: 379 -DEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTAC-FQ 552
DEKDCP T C + N F CAD RQC + KCDG DC D SDE + C +
Sbjct: 1088 QDEKDCPPIT--CLA-NQFKCADLRQCVEEPYKCDGIPDCNDGSDELGCPTMEPNQCNLE 1144
Query: 553 YQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDY 732
FRC CI +W CDGS DC D SDE D C C ++C N +C + + CD
Sbjct: 1145 KHFRCRSSGVCIPIAWHCDGSNDCDDHSDEED-CSKITCPNGFYKCANAKCVFKAYICDG 1203
Query: 733 YDDCGDNSDED-----ECGEYRCPPGKWNCPG-TGHCIDQLKLCDGSKDCADGADE-QQC 891
DDCGD SDE RC G+W CPG T C++ +CD DC +GADE C
Sbjct: 1204 KDDCGDGSDESVEHACVTPPQRCAHGQWACPGVTERCVNLTSVCDDVPDCPNGADEGLGC 1263
Query: 892 SQNLCPSLG--CQAGCHPSPHGGECTCPSGYKL-DDRFHRTCSDINECAEFGYCDQLCAN 1062
C C GC +P G C CP G +L D F TC D+NEC G C Q C N
Sbjct: 1264 DLAQCQHQTGLCSNGCQKTPLGALCICPPGEELAPDNF--TCKDLNECDPPGLCSQRCTN 1321
Query: 1063 HRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPD 1242
+ + CSC+ D + L+ P K C + N L ++ R + + K
Sbjct: 1322 TKGSYFCSCV-DGYVLE----PNKHT------CKAVNHPAAFLIISNRHSILVADLKEQG 1370
Query: 1243 -EEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYP 1419
E V + + G IFW+D D E + ++ L
Sbjct: 1371 LERVPIIVENVVATASNMHTG--TIFWSDMKLKKISRLDRGMEPQ-----EIISTGLDLV 1423
Query: 1420 RCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALD--PLRGEMFFT 1593
LA DWI LY ++S I+V+ +G R VL+ + +T P + LD P +F+T
Sbjct: 1424 EGLAYDWIGQNLYWLDSKLNTIEVAHENGSNRLVLVRENITQPRGMCLDPSPTAKWLFWT 1483
Query: 1594 N---QLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGND 1764
+ ++E MDGT R T+V+T + +G+ +D+ +RVY+ D K+D ++ Y G
Sbjct: 1484 DWGENPRIERIGMDGTMRETIVSTKIYWPNGLTLDVATQRVYFADSKLDFIDFCYYNGTG 1543
Query: 1765 RRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGI 1944
R+ V + + H L+LF+ LYWTD V+ K+ + + S+ + P+ +
Sbjct: 1544 RQQVLAASHYLLHAHSLSLFEDTLYWTDRQLNRVLSAHKYRGTNQTVVSHLISQ--PLSV 1601
Query: 1945 SAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNG 2124
+HP QP E+PC A C+ +C+LS GY C C G +L+
Sbjct: 1602 HVHHPSLQP----------MYESPCKRAACQHVCLLSPSE---PAGYACKCRPGYRLLPE 1648
Query: 2125 KRCIDSID--YLLFSSNKIVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGN 2298
RC + + +L N+IV P A + ++P+ I ++ D G
Sbjct: 1649 GRCTEEENAFIMLLKGNQIVD--VPFNGGDARSSGLMPVVGIEGG-----ISLDYDRKGE 1701
Query: 2299 SFFYADIMDN------TIYRIRPDGEGAAPVLVTHNDGL----FSMSFDWISKQLYYVDN 2448
++ D TIY P G G + + GL ++++FDWI + LY +
Sbjct: 1702 MVYWVQGRDESDDENCTIY-ATPYGGGNRTEFLGPDTGLVGAAYTIAFDWIGRNLYVGNR 1760
Query: 2449 IRNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKGLLFYAEAMRPAAIYR-- 2622
+ +++E + + L T + P + + P G LF+ + + +
Sbjct: 1761 LASNIEAISVDGKVRYRTVVLANDGNRTSVAKPKQLALDPADGRLFWIDEGGFGVLTKVA 1820
Query: 2623 -CHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKNV-VKLDIDN 2796
+DG + +V+ + T+ P + +D + R+ + L + +++DG L +N
Sbjct: 1821 SAGMDGSDPRVL-DDTVQFPESITVDAEKRRVYYSTRLPPAVLSIEYDGTGQRTILSEEN 1879
Query: 2797 PI--PVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQ 2970
I P A+ ++ +Y++ + RV NG +K++ + D R + + S
Sbjct: 1880 AISKPRALAVLESRLYFLDPTYEKLARVDLPNGDNAKLILDNEPDLRQMVIYRKRS---- 1935
Query: 2971 PIPDDSREHPCRASQ--CTQLCFATPSESHPNELEAKCACRQGFMINKENNHSC 3126
S +HPC + C LC S CAC G+ KEN +C
Sbjct: 1936 -----SLQHPCTQNNGGCEHLCLPHAGASR------VCACGVGY--KKENEVAC 1976
Score = 285 bits (728), Expect = 3e-74
Identities = 208/699 (29%), Positives = 308/699 (43%), Gaps = 44/699 (6%)
Frame = +1
Query: 136 VNTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQC--DTYT 309
++ A C +N FRC + +CI W P CKS+ C D +T
Sbjct: 2771 LHCAQRTCPQNSFRCPNHRCIPATW---YCDGDDDCGDGADEPPEYCKSEGRTCFGDLFT 2827
Query: 310 WHSVSCIAEYQRCDNITDCADGSDEKD-CPASTVDCSSQNVFMCADGR-----QCFDVSK 471
+ +CI CD DC D SDE + + C F C + + QC
Sbjct: 2828 CDNGNCIPRIYICDGDNDCLDNSDEDNRHQCNDRKCDEDTEFTCHENKAWARAQCIPKKW 2887
Query: 472 KCDGKYDCRDLSDEKDSCSR--NHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEP 645
CDG DC D +DE + + C + F CA+ +CI + WVCD DC DGSDE
Sbjct: 2888 ICDGDPDCVDGADENTTLQHCPSPQPCGEDMFTCAN-GRCINQGWVCDHDNDCGDGSDEG 2946
Query: 646 DTC--EFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDEC--GEYRCPPGKWNCPG 813
C ++K CT EF C+N +C ++RCD DDCGD+SDE C C GK+ C
Sbjct: 2947 KNCNSQYKTCTPQEFTCQNFKCIRNQYRCDGEDDCGDHSDEVGCKKDNATCAEGKFTC-N 3005
Query: 814 TGHCIDQLKLCDGSKDCADGADEQ-QCSQNLCPSL---GCQAGCHPSPHGGECTCPSGYK 981
G CID +C+ DC D +DE C+ + C + C C + C C GYK
Sbjct: 3006 NGQCIDYHLVCNKVPDCTDESDEPLHCNVDECAKVEIHRCGHKCVDTLTSYYCDCNQGYK 3065
Query: 982 LDDRFHRTCSDINECAEF-GYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGY 1158
L + + C+DI+EC E G C Q C+N G+ C C + Q + K + +
Sbjct: 3066 LLED-GKACADIDECIETPGVCSQHCSNTPGGYYCKCDERYYERQNDEHTCKRKDDTKPW 3124
Query: 1159 CVSNNADKMKLFVARREGLYRLNPKNPDEEVKKLASGEF--IYGIDFDYGDRKIFWTDRL 1332
+ +N Y + + D L + + IDFD ++++ D
Sbjct: 3125 LIFSNK-------------YYVRNMSTDGHQYNLIHQDLMNVVAIDFDMQQHEMYFCDVT 3171
Query: 1333 A----HSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSY 1500
A S+F + V+D I + + S +A+DW+ LY ++ S+ +DV+
Sbjct: 3172 AKTIFKSSFGSLVEDGVRIEKTPVIKHDSHGL-EGIAIDWVGRKLYWLDRHSKNLDVAEL 3230
Query: 1501 DGERRTVLLADGLTLPLDIALDPLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHTHQV 1671
DG RR L G+ P I + P G ++FT+ Q + MDG+N T + T +
Sbjct: 3231 DGTRRKT-LRSGVVDPRAIVVHPGIGYLYFTSWHLQAYIAKMGMDGSN-FTRILTWEDDI 3288
Query: 1672 ---SGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYW 1842
+ + +D R+YW D +D + D +G R +V G VPH F L++FD LYW
Sbjct: 3289 AWPNALTIDYFTDRIYWADAHLDYIAFADLEGRHRHVVLSGAR-VPHVFALSIFDDSLYW 3347
Query: 1843 TDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPC- 2019
TDW +++ KF + NT + + + IS HP+ Q + NPC
Sbjct: 3348 TDWNLKAILRANKFTGANYTVVRNTTHRPYDVHIS--HPLRQ----------IPFPNPCG 3395
Query: 2020 -TNADCEGMCILSKD--------NGGFGVG---YKCACP 2100
TN C +C+L+ G G Y+CACP
Sbjct: 3396 TTNGGCSHLCLLAPPLESTYLNVEGYLEEGAPSYRCACP 3434
Score = 256 bits (655), Expect = 9e-66
Identities = 193/670 (28%), Positives = 291/670 (42%), Gaps = 22/670 (3%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAE 336
C+E++FRC++GKCI + W GC+ Q + T+ S CIA
Sbjct: 3700 CSESEFRCDNGKCISSRWRCDHEDDCGDNSDEY-----GCEGFQCKNGTFQCKSGHCIAA 3754
Query: 337 YQRCDNITDCADGSDEKDCPASTVD--CSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSD 510
Y RCD DC D SDE CP ++ F CA+ C S CDG DC D SD
Sbjct: 3755 YFRCDGDRDCRDMSDEIGCPPRFPGGRYCPESRFQCAN-NLCVLPSDLCDGTDDCGDNSD 3813
Query: 511 EKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPD----TCEFKKCTA- 675
E S N +F+CA+ +C+ + +CDG +C DGSDE + K C
Sbjct: 3814 EAASVCTNFNCDTLRRFQCANH-RCVARYQICDGVDNCGDGSDENNMTLCAARQKPCDLY 3872
Query: 676 NEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGS 855
++QC NK+C R CDY DDCGD SDE C T C
Sbjct: 3873 TQYQCANKKCIDRAQVCDYADDCGDGSDE------------LGCHRTASC---------- 3910
Query: 856 KDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEF 1035
+ GC+ C G C C +G+ +D + C+DI+ECA
Sbjct: 3911 --------------SALNKGGCEHHCVNLTDGYICACYAGFIIDASNKKRCTDIDECATG 3956
Query: 1036 GY-CDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREG 1212
+ C LC N + C C + F L + G C + + + + E
Sbjct: 3957 THGCSHLCTNLNGTYECGC-REGFRLSDR---------VSGVCKALKGEPLLVLSGGPE- 4005
Query: 1213 LYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTD----RLAHSAFSADVDDEGEIS 1380
R + + +A + I +D++ + IFWTD + S ++ + ++
Sbjct: 4006 -IRAYEPAQNRQFDVIAGEKRIEALDYNPESQMIFWTDSYDKTIKRSYMVNAMNGDAKVG 4064
Query: 1381 QIKKLSLKSLVYPRCLAVDWITNTLYIIE---SGSR---RIDVSSYDGERRTVLLADGLT 1542
+ L++K P LAVDW+ + LY E +GS+ RI V+ DG R L+ GL
Sbjct: 4065 YAQDLNMKGGTKPTALAVDWVADNLYWAETDRTGSKPRGRIMVAKTDGRYRRALVQAGLE 4124
Query: 1543 LPLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKR-VY 1710
+P IA+DP G MF+ + K+E + MDG+ RR ++ +G+ VD + VY
Sbjct: 4125 VPTAIAVDPQLGRMFWADAGSAPKIEVSWMDGSKRRPIITEAIRHPAGLTVDYSQDHAVY 4184
Query: 1711 WVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFGS 1890
WVD K++ +E + G RR V +G +++ HP L +F+ LYW +++ +KFG
Sbjct: 4185 WVDTKLNTIEVMKPDGTMRRTVLKG-DLLKHPVSLDVFESSLYWVTRDTGELLRQDKFGR 4243
Query: 1891 DTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGG 2070
++ + N P I YH + + NPC C +C+L
Sbjct: 4244 GVQV--TVQRNLANPSSIKVYHELR---------YNTTLNNPCYRNPCSHLCLLVPG--- 4289
Query: 2071 FGVGYKCACP 2100
G +C+CP
Sbjct: 4290 ---GRRCSCP 4296
Score = 153 bits (387), Expect = 1e-34
Identities = 109/362 (30%), Positives = 151/362 (41%), Gaps = 58/362 (16%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAE 336
C F+C +G C + P C ++C + S CI +
Sbjct: 3492 CRAGTFQCGNGNCTPSTTICDGTDDCGDGTDEQNCDLP-CPVSDFKCKS----SGRCILD 3546
Query: 337 YQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGR------------QCFDVSKK-- 474
+CD DC DGSDE C + F C +GR C D S +
Sbjct: 3547 SWKCDGDADCKDGSDEDPEICHKRTCDPETEFSCKNGRCIPKLWMCDFDNDCGDDSDEPA 3606
Query: 475 -----------------------------CDGKYDCRDLSDE-KDSCSRNHTACFQYQFR 564
CDGK DCRD SDE ++C + + + F+
Sbjct: 3607 YMCRQRNCTTGWSRCPGQSNYRCIPKWLFCDGKDDCRDKSDELPENCPQCNQ---ETDFK 3663
Query: 565 CADKTQCIQKSWVCDGSKDCADGSDEPDT-C--EFKKCTANEFQCKNKRCQPRKFRCDYY 735
C + +CI + W+CD + DC DGSDE +T C ++++C+ +EF+C N +C ++RCD+
Sbjct: 3664 C-NNNRCIPRQWMCDFADDCGDGSDESETQCKGKYRECSESEFRCDNGKCISSRWRCDHE 3722
Query: 736 DDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNL---- 903
DDCGDNSDE C ++C G + C +GHCI CDG +DC D +DE C
Sbjct: 3723 DDCGDNSDEYGCEGFQCKNGTFQCK-SGHCIAAYFRCDGDRDCRDMSDEIGCPPRFPGGR 3781
Query: 904 -CPSLGCQAGCHPSPHGGECTCPSGY--KLDDRFHRTCSDINECAEFGYCDQL----CAN 1062
CP Q C PS DD + + C F CD L CAN
Sbjct: 3782 YCPESRFQCA------NNLCVLPSDLCDGTDDCGDNSDEAASVCTNFN-CDTLRRFQCAN 3834
Query: 1063 HR 1068
HR
Sbjct: 3835 HR 3836
Score = 150 bits (380), Expect = 7e-34
Identities = 104/341 (30%), Positives = 143/341 (41%), Gaps = 26/341 (7%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXX--PHPGCKSDQWQCDTYTWHSVSCI 330
C+ + F C +GKCI W C +++++C + CI
Sbjct: 2612 CDASKFYCQNGKCISRMWSCDGDDDCGDGSDEDVNYCAFHSCAANEFRCA-----NGRCI 2666
Query: 331 AEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRD--L 504
+ +CD+ DC DGSDE+ C S C F CA+GR C ++ C+G DC+D
Sbjct: 2667 FKSWKCDHENDCKDGSDEEGC--SYPPC-VDGEFTCANGR-CIPQAQVCNGVNDCKDNGT 2722
Query: 505 SDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDE-PDTCEFKKCTANE 681
SDE +T C +C C++ W+CDG DC D SDE P C + C N
Sbjct: 2723 SDETHERCPTNTTCPPNHLKCDRTNICVEPYWLCDGDNDCGDNSDENPLHCAQRTCPQNS 2782
Query: 682 FQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPG------TGHCIDQLKL 843
F+C N RC P + CD DDCGD +DE EY C C G G+CI ++ +
Sbjct: 2783 FRCPNHRCIPATWYCDGDDDCGDGADEPP--EY-CKSEGRTCFGDLFTCDNGNCIPRIYI 2839
Query: 844 CDGSKDCADGADE---QQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSD 1014
CDG DC D +DE QC+ C + CH + C + D
Sbjct: 2840 CDGDNDCLDNSDEDNRHQCNDRKCDE-DTEFTCHENKAWARAQCIPKKWICDGDPDCVDG 2898
Query: 1015 INECAEFGYCDQ---------LCANHR---PGFTCSCLGDC 1101
+E +C CAN R G+ C DC
Sbjct: 2899 ADENTTLQHCPSPQPCGEDMFTCANGRCINQGWVCDHDNDC 2939
Score = 140 bits (354), Expect = 7e-31
Identities = 117/423 (27%), Positives = 157/423 (36%), Gaps = 72/423 (17%)
Frame = +1
Query: 142 TASSVCNENDFRC--NDGKCIRTEWXXXXXXXXXXXXXXXXX-PHPGCKSDQWQCDTYTW 312
T + C RC +D KCI W P C++ +QC
Sbjct: 3445 TCIANCTSGQHRCGGDDEKCIPWFWKCDGEPDCKDRSDEPASCPARHCRAGTFQCG---- 3500
Query: 313 HSVSCIAEYQRCDNITDCADGSDEKDC--PASTVDCSSQNVFMCADGRQCFDVSKKCDGK 486
+ +C CD DC DG+DE++C P D F C +C S KCDG
Sbjct: 3501 -NGNCTPSTTICDGTDDCGDGTDEQNCDLPCPVSD------FKCKSSGRCILDSWKCDGD 3553
Query: 487 YDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPD-TCEFK 663
DC+D SDE T + +F C + +CI K W+CD DC D SDEP C +
Sbjct: 3554 ADCKDGSDEDPEICHKRTCDPETEFSCKN-GRCIPKLWMCDFDNDCGDDSDEPAYMCRQR 3612
Query: 664 KCTA-------------------------------------------NEFQCKNKRCQPR 714
CT +F+C N RC PR
Sbjct: 3613 NCTTGWSRCPGQSNYRCIPKWLFCDGKDDCRDKSDELPENCPQCNQETDFKCNNNRCIPR 3672
Query: 715 KFRCDYYDDCGDNSDEDEC---GEYR-CPPGKWNCPGTGHCIDQLKLCDGSKDCADGADE 882
++ CD+ DDCGD SDE E G+YR C ++ C G CI CD DC D +DE
Sbjct: 3673 QWMCDFADDCGDGSDESETQCKGKYRECSESEFRC-DNGKCISSRWRCDHEDDCGDNSDE 3731
Query: 883 QQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFH----RTCSDINECAEFG---- 1038
C C + G C SG+ + F R C D+++ E G
Sbjct: 3732 YGCEGFQCKN-------------GTFQCKSGHCIAAYFRCDGDRDCRDMSD--EIGCPPR 3776
Query: 1039 -----YCDQ---LCANH---RPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKM 1185
YC + CAN+ P C DC G ++ C + N D +
Sbjct: 3777 FPGGRYCPESRFQCANNLCVLPSDLCDGTDDC---------GDNSDEAASVCTNFNCDTL 3827
Query: 1186 KLF 1194
+ F
Sbjct: 3828 RRF 3830
Score = 134 bits (338), Expect = 5e-29
Identities = 73/198 (36%), Positives = 99/198 (49%), Gaps = 2/198 (1%)
Frame = +1
Query: 304 YTWHSVSCIAEYQRCDNITDCADGSD-EKDCPASTVDCSSQNVFMCADGRQCFDVSKKCD 480
+T ++ CI + CD DC D SD E++C T C + N F C GR C ++ +CD
Sbjct: 944 FTCNNQRCIPKSWICDGDDDCLDNSDEEQNCTKPT--CGT-NEFQCKSGR-CIPLNFRCD 999
Query: 481 GKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEF 660
+ DC D SDE + + C QF C + +CI W CD DC DGSDE C
Sbjct: 1000 QENDCGDHSDEFEC---GNVTCAASQFAC-ENGRCIPNIWKCDSENDCGDGSDEGPFCAE 1055
Query: 661 KKCTANEFQC-KNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQL 837
K C +F C + C P+ + CD DDC D DE +C C ++ C C+++
Sbjct: 1056 KTCAYFQFTCPRTGHCIPQSWVCDGDDDCFDKQDEKDCPPITCLANQFKCADLRQCVEEP 1115
Query: 838 KLCDGSKDCADGADEQQC 891
CDG DC DG+DE C
Sbjct: 1116 YKCDGIPDCNDGSDELGC 1133
Score = 66.2 bits (160), Expect = 2e-08
Identities = 44/145 (30%), Positives = 61/145 (41%), Gaps = 6/145 (4%)
Frame = +1
Query: 151 SVCNENDFRCNDG-KCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSC 327
+ C + FRC +G +CI T P C Q++C + C
Sbjct: 82 TACRLDQFRCANGVRCIDTALKCNHKNDCGDNSDEVGCNFPPCHGGQFRCA-----NALC 136
Query: 328 IAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADG-----RQCFDVSKKCDGKYD 492
I CD DC+D SDE +C A + C N F+C G +C SK CDGK D
Sbjct: 137 IPATFHCDGYHDCSDESDEANCTA--IAC-PDNKFLCPRGGPNGQAKCIVKSKLCDGKRD 193
Query: 493 CRDLSDEKDSCSRNHTACFQYQFRC 567
C D +DE+ +CS + +C
Sbjct: 194 CDDGTDEETACSTTSCPALGCEHKC 218
>gi|24640820|ref|NP_572563.2| CG12139-PB [Drosophila melanogaster]
gi|7291057|gb|AAF46494.1| CG12139-PB [Drosophila melanogaster]
Length = 4547
Score = 2841 bits (7364), Expect = 0.0
Identities = 1668/4715 (35%), Positives = 2444/4715 (51%), Gaps = 144/4715 (3%)
Frame = +1
Query: 454 CFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADG 633
C K+CDG DCR DE CS AC QFRCA+ +CI + C+ DC D
Sbjct: 43 CVPKEKRCDGYLDCRTGRDEV-GCSG--VACRLDQFRCANGLKCIDAALKCNHRDDCGDN 99
Query: 634 SDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCP- 810
SDE C F C +F+C N C P F CD Y DC D SDE C CP K CP
Sbjct: 100 SDEQG-CNFPPCHHAQFRCTNALCIPYNFHCDGYHDCADKSDEANCTAIACPDNKHLCPR 158
Query: 811 ----GTGHCIDQLKLCDGSKDCADGADEQ-QCSQNLCPSLGCQAGCHPSPHGGECTCPSG 975
GT CI + +LCDG +DC DG+DE+ CS CP+L C+ C PS GG C C G
Sbjct: 159 GGASGTPKCILKSQLCDGKRDCEDGSDEETNCSIASCPALSCEFKCGPSLTGGVCYCKPG 218
Query: 976 YKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRG 1155
L +RTC D++ECAE+G+CDQLC N +TC C +TL +
Sbjct: 219 QSLAPD-NRTCVDLDECAEWGHCDQLCTNTLGSYTCQC-AQGYTLIND-----------S 265
Query: 1156 YCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLA 1335
C++ +A+ ++L A + R+ P E K LA+ G+ F Y ++W+D
Sbjct: 266 KCIAPDANNLQLIFAHDRAIMRMLPHG--SEPKILANATAAAGVTFHYARNTLYWSDIKT 323
Query: 1336 HSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERR 1515
S +D + + +L P LAVDW+ + +Y+ + ++IDV G+
Sbjct: 324 RKVQSLPLDAQNKAVSPFDQTLPGTWAPVALAVDWVGDKIYVADLVGQKIDVFELSGQWH 383
Query: 1516 TVLLADGLTLPLDIALDPLRGEMFFTNQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDIT 1695
V+L LT P D+ALDP G MF + ++ A MDGT+ R++V+ ++ SG+ VDI
Sbjct: 384 AVVLGSNLTSPADLALDPTAGLMFVADGGQVLRAHMDGTHARSIVSEAAYKASGVTVDII 443
Query: 1696 AKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQV 1875
+KRV+W D +D +ES+DY+G R +V +G V P P LALF+ +YWTD T+ G++ V
Sbjct: 444 SKRVFWCDSLLDYIESVDYEGAHRVMVLRGQQV-PSPSRLALFENRIYWTDATKQGIMSV 502
Query: 1876 EKFGSDTKLLWSNTENNVF-PMGISAYHPMAQPGPGQSECLAMKIENPC--TNADCEGMC 2046
+KF T + + ++ P GI A H ++QP ++ NPC N C MC
Sbjct: 503 DKFEGPTSIQVTYKAKDIREPKGIIAVHALSQP----------RVSNPCGNNNGGCNHMC 552
Query: 2047 ILSKDNGG-FGVGYKCACPIGQKLVNG-KRCIDSIDYLLFSSNKIVRGIFPEINEKALAE 2220
I++ G G+G++CAC G +L K C ++L++S + ++G E + ++
Sbjct: 553 IVTAVKGAPTGLGFRCACSTGYQLETDLKLCKPVSEFLMYSQQRFIKGKVLEPVIEGFSD 612
Query: 2221 AVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLF 2400
A++P+ R +G+ F D +Y+D++ + IYR+ +G G VL + N+G+
Sbjct: 613 AIMPVVSRRARFVGLDF----DARDEFIYYSDVLQDVIYRVHRNGTGREIVLASQNEGVE 668
Query: 2401 SMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKGL 2580
++ DW SK LYY+D+ + +L V + + H RR L+ L+ P ++VVHP +G
Sbjct: 669 GLAVDWASKNLYYIDSRKGTLNV--LSTRNVTH-----RRTLLKNLKRPRAIVVHPNRGF 721
Query: 2581 LFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDF 2760
+F++E RPA I R + DG V +N TLG P+ ++IDF E+R+ W D LL + +
Sbjct: 722 IFFSEWDRPANITRANTDGSGLLVFKNVTLGWPNGLSIDFKEDRVYWCDALLDHVQHANL 781
Query: 2761 DGKNVVKLDIDNPI-PVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKI-VREFGADERS 2934
DG ++ ++ P +I I N+++Y R +I R+HK G ++ VRE
Sbjct: 782 DGTDIKTVNSRLVRHPFSIVIHNDWMYITDWRLDAIIRLHKLTGEQEEMMVRE--PQTNR 839
Query: 2935 IFSLKACSHQNQPIPDDSREHPCRASQ--CTQLCFATP----------SESHPN--ELEA 3072
++ +K SH+ Q I D PC + C ++CFA P + S P+ L++
Sbjct: 840 LYGVKVYSHEVQRIADTQ---PCHRNNGGCQKICFAVPIGASNGTDGVTTSSPSFGRLQS 896
Query: 3073 KCACRQGFMINKENNHSCQKDP-AEKIEQLCSSNSTQFQCKNGRCIPKEWKCDGENDCLD 3249
+C+C G + ++ SC DP AE Q C NS F C N RCIPK W CDG++DCLD
Sbjct: 897 RCSCPYGERL-ADDQVSCIPDPSAEPPVQPCP-NSWDFTCNNQRCIPKSWLCDGDDDCLD 954
Query: 3250 ESDEIDEKGDKCFHETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQK 3429
SDE C T C N +CR+ + CIP ++
Sbjct: 955 NSDE----EQNCTKPT-CGSNEFQCRSGR-CIPQNFRCDQENDCGDNSDE-----QECGN 1003
Query: 3430 PVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNATCAANQFSCAN-GRCIPI 3606
C +F C N RCIP WK E + C TCA QF+C G CIP
Sbjct: 1004 VTCGTSQFACANGRCIPNMWKCDSENDCGDSSDEG-DFCAEKTCAYFQFTCPRTGHCIPQ 1062
Query: 3607 YWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQCVPLRNHXXXXXXXXXXXXXXX 3786
W+CDGD+DC+D DE + CPP+ C A QF+CA+ RQCV
Sbjct: 1063 SWVCDGDDDCFDKQDE--KDCPPISCLANQFKCADLRQCV----EESYKCDGIPDCNDGS 1116
Query: 3787 XAVTAESCTPDQ------FKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSD 3948
V S P+Q F+C S+G CIP +W SDE G + C+ +
Sbjct: 1117 DEVGCPSMGPNQCNLEKHFRCKSTGFCIPIAWHCDGSNDCSDHSDEQDCGQIT---CAQN 1173
Query: 3949 QFKCGNGRCILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPL 4128
FKC N C+ ++CDG++DCGD SDE +E C KCP C E C+ +
Sbjct: 1174 FFKCNNTNCVFKAYICDGKDDCGDNSDEGAEHACVPP--PFKCPHGQWQCPGVSERCVNI 1231
Query: 4129 HQLCDGKTHCPGGTDEGGRCARDLCSADRAGCSFKCHNSPNGPICSCPFGEQL-VNKTKC 4305
+CD CP G+DEG C C CS C +PNG +C CP G ++ + C
Sbjct: 1232 TSVCDDTPDCPNGSDEGEGCDLAECEHQAGQCSSFCQKTPNGALCVCPPGSEIGEDGYTC 1291
Query: 4306 EPENECLDSSSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIY 4485
NEC CSQ+C + K + CSC +GY L+ +K TCK ++ I +SNR+ I
Sbjct: 1292 IDSNECDPPGLCSQQCTNTKGSYFCSCTDGYVLEPNKHTCKAVNHTAAFLI-ISNRHSIL 1350
Query: 4486 YSDHKLDNWHTFGAIVENAIALAWDSLTDRIYWSDIREKKILSANRNGTNATVFIADGLD 4665
+D K IVEN +A A + T I+WSD++ KKI +R G I GLD
Sbjct: 1351 VADLKEQGLERVPIIVENVVATASNMHTGTIFWSDMKLKKISRLDR-GMEPQEIINTGLD 1409
Query: 4666 ITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGV--M 4839
+ EG+A DW+ +NLYW+DS LNTIEV+ E+ R +LV +N++QPRG+ +DP G +
Sbjct: 1410 LVEGLAYDWIAQNLYWLDSKLNTIEVS-AENGSNRLVLVRENITQPRGMCIDPSPGARWI 1468
Query: 4840 FWTDWGQNPCIERASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYD 5019
FWTDWG+NP +ER MDGT R+ I+ TKIYWPN + LD T RVYFADSKLDFIDF Y+
Sbjct: 1469 FWTDWGENPRVERIGMDGTMRKTIINTKIYWPNGLTLDIATKRVYFADSKLDFIDFCYYN 1528
Query: 5020 GSGRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKAL 5199
G+GR QVLASS ++ HPH+L++FED +Y++DR+L ++ K+ G SH S+ L
Sbjct: 1529 GTGRQQVLASSHYLLHPHSLSLFEDTLYWTDRQLNRVLSANKF-RGKNQTVVSHLISQPL 1587
Query: 5200 GVVAVHPVLQPVIKNNPCSTNPCSHLCLLNNK--NTFTCKCPMGEKLDASGKKCIDDAKP 5373
+ H LQP+ N PC+ + C HLCLL+ ++CKC G KL + G+ CI++ P
Sbjct: 1588 SIHVHHASLQPMTPN-PCAGSRCQHLCLLSPSAPEGYSCKCRPGFKLLSEGR-CIEEENP 1645
Query: 5374 FLVIIQKTNVFGIEMNSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAK 5553
FL++++ T + + +N + + P+ G+ ++ +D E ++ ++
Sbjct: 1646 FLMVVKGTQIVDLPLNGGDARA----GALAPVIGIESSTGLDFDRKGETLYWVQGREDDD 1701
Query: 5554 TLAQITTDSAIYRSTVNGGNKTKMFS--SAVPDDAYCLGFDWNGRNLVVGNKITQTIEII 5727
+ IY + GGNKT + + Y + FDW GRNL +GN++ IE +
Sbjct: 1702 E------NCTIYTTPYGGGNKTLFLGIENGIVGAPYTIAFDWLGRNLYIGNRVASNIEAV 1755
Query: 5728 RTQGKQ-YRSVILSNDQSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSN 5904
R GKQ YR++IL+ND +G +FW+D G K+ R ++G N
Sbjct: 1756 RVDGKQKYRTIILANDGYPNSVSRPKQIALDPTEGKLFWIDEGVLEVPIKIGRVDMNGQN 1815
Query: 5905 PLVIASNDLAELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGR---QPNG 6075
P+V+ + A + +A+DT VY+S + I + Y+G D +L +P
Sbjct: 1816 PIVVFQ-EFAHPESLAVDTEKKMVYYSASNPAVIGVMDYNGDDHTLILMKDSHPMAKPRS 1874
Query: 6076 LAFYGDRLFYADSAFDSIEVATINGDSQPPQWTHFKKDVENLANIKALQ--PRASSSGHP 6249
L RL+Y D ++ I + P K V+N ++++++ + + HP
Sbjct: 1875 LGILDHRLYYLDPLYERIVRIDLPHGDNP------KTIVDNESDLRSMMIYKKRALMQHP 1928
Query: 6250 CHINNGNCDHICIPLMFAQRTCTCANGYVKDGQTSCKLFDESFVIVATKTKVIGYPIDET 6429
C NNG C H+CIP A RTC C GY K+ + +C + + F +V+ + GY + ++
Sbjct: 1929 CQTNNGGCKHLCIPGPGATRTCACGIGYRKENEINCVAY-KIFAVVSQLDMIRGYSLSDS 1987
Query: 6430 QSKGVAMEPIGGLS--ITGVDYDYESKTIYVAEAS-GINKGITAYTIGESSPRAVIRDSI 6600
AM PI G I VD Y + IY AE + G GI + + V++D I
Sbjct: 1988 SE---AMVPISGPGHHILHVDVMYREQWIYWAEYNRGYWNGIFRSRPNGTDLQHVVKDGI 2044
Query: 6601 GSLTIKSLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSR 6780
GS I+ L IDW+ NMYF N +EV LDG+ RK+L+ T T+ P +AV+P+ R
Sbjct: 2045 GSNGIRGLTIDWVAGNMYFTNVYPHENYVEVCWLDGSNRKVLVKTTTDAPRELAVNPIKR 2104
Query: 6781 YLYWADQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVR 6960
LYW D GQ P I ++ LDGS+ +V+SGI+ P DL +D+ + IYW D+K+D I ++
Sbjct: 2105 LLYWIDYGQHPRIGKALLDGSKWTPLVTSGISLPRDLTIDMQTHDIYWVDSKLDTIQKIS 2164
Query: 6961 STGGTPELVRSDIASAAGVALHGQNMYWTDNRLEKLFRATS-KPNQTSLLLSPTTVAASL 7137
G +++R D+ + G+A++ ++YW D L +F+A+ N+T+ T+V +L
Sbjct: 2165 YNGANRKIIRRDLPNPMGIAVYLNDVYWVDRNLMTVFKASKHSANETA-----TSVRTNL 2219
Query: 7138 KDIGDVAVFSSNNQPR-ASSPCQITDNLRKSPCTQLCFATP---------GTQTPTCSCA 7287
+ + D+A+++ NNQP+ ++PC +L C QLCF+ P G + C CA
Sbjct: 2220 EKLRDIAIYNINNQPQDDTNPCA---HLGNGGCDQLCFSFPPDGGASGTSGGRNFRCECA 2276
Query: 7288 RGVLKG--RTCEEPDTYIMFSDGDKIIDVAIEPDVKASRPLKDPFPEISNLQTFDVDVNL 7461
G L R CE + Y++F+ +I V ++P ++ P ++N+ D D
Sbjct: 2277 TGKLSADERKCEVVNEYLVFATRTEIRAVNLDP--HSTEVPFTPLTNLTNVVGLDFDFAH 2334
Query: 7462 RRVYFVVESPVGVNISWFSMNNAENPRLVFGASKQPHAKEIRHISDMKLDWLTQKIYFTT 7641
R+ + P I++ N + + +K + + I + DW QKIY+T
Sbjct: 2335 NRMLYTQIRP-WAKIAYTKANKPGHDDITVVLNKGINPEGIAY------DWTQQKIYWTD 2387
Query: 7642 GRGGKVMAIDTAGEHLSTIASGDWTYALAIDPCSGLLFWSDSG-YKTSGGLYEPRIERSN 7818
+ A++ G L IA + A+ +DPC+G LF++D G + TSG +I R+
Sbjct: 2388 SSNNSIYAMNLDGSELVMIARVERPRAIVLDPCNGTLFFTDWGRFGTSG-----KIFRTT 2442
Query: 7819 LAGGSRKVIVSESISLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRK-VIASGYRAK 7995
+AG ++ IV + +S P+ +A+D+ +++YW D R IE +D DGQNR+ ++A+
Sbjct: 2443 MAGSLKRAIVDKDLSQPSGLAIDYDERRLYWTDAVREKIERSDLDGQNRELLVAATIYPF 2502
Query: 7996 SLDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVSD-RRIPGALRVFASESDVRTRNQVC 8172
++ ++ ++Y +D GV+R +K +G+ + +V P +R+++S+ Q C
Sbjct: 2503 AITVFRNYIYWTDLQLRGVYRAEKHTGANMVEMVKRLEDSPRDIRIYSSD------RQKC 2556
Query: 8173 NALTSQLCKTDNGGCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGS 8352
N C+ +NGGC Q C + K +C C+D+ ++V E C R +
Sbjct: 2557 NV---NPCRINNGGCAQSCHPAPN------GKAECKCDDSTKVVNE-----GRMCAPRNN 2602
Query: 8353 NSEPAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNR 8532
E +K F C +G CI +CD DC D SDE+PNYC SC + C N
Sbjct: 2603 TCEASK-------FYCKNGRCISRMWSCDGDDDCGDNSDEDPNYCAYHSCSPNEFRCNNG 2655
Query: 8533 RCIDSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQV 8712
RCI + KC+H +DC DGSDEL C C +G F C+NG CI Q +VC+G NDC D
Sbjct: 2656 RCIFKSWKCDHENDCKDGSDELGCVYP-PCVDGEFTCANGRCIPQAQVCNGVNDCKDNAT 2714
Query: 8713 SDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQH 8892
SDE+ CP + C ++C TNIC++P LCDG +DCGD +DE+ L C + C +
Sbjct: 2715 SDETHERCP-MNTTCPANHLKCEKTNICVEPYWLCDGDNDCGDNSDEDPLHCGQRTCPTN 2773
Query: 8893 YVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAF 9072
RCP+ RCIP TW CDGD+DC DG DE C + C GD LF CDN CI R +
Sbjct: 2774 SFRCPNHRCIPATWYCDGDDDCGDGADEPPDYCKSEG--RTCFGD-LFTCDNGNCIPRIY 2830
Query: 9073 IXXXXXXXXXXXXXHSRHGCGNRTCTDQ-EFHCTSNAKLAQPKYECIPRAWLCDGDVTCA 9249
I +RH C +R C ++ EF C N + + +CIP+ W+CDGD C
Sbjct: 2831 ICDGDNDCLDNSDEDNRHQCNDRKCDEETEFTCVENK--SWQRAQCIPKKWICDGDPDCV 2888
Query: 9250 GGEDESTEL--CKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDE--HANCTYSS 9417
G DE+T L C T+ + C + F C N CI+ W CD DNDC DG+DE N Y +
Sbjct: 2889 DGADENTTLHNCATQ-QPCGEDMFTCGNGRCINKGWICDHDNDCGDGTDEGKFCNSKYKT 2947
Query: 9418 CQPDFFQCANHKCVPNSWKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTSGEC 9597
C F C N KC+ N +CDG DDC D SDE C K + + C GQF CT+G+C
Sbjct: 2948 CSAQEFTCQNFKCIRNQSRCDGEDDCGDHSDEVGCAKENIT------CPQGQFACTNGQC 3001
Query: 9598 IDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDIS 9777
ID VC++ DC D SDE + C +DEC+ E C KC+D GY CDC EG+ + ++
Sbjct: 3002 IDYNLVCNKYPDCADESDEPAHCNVDECAKVEINQCGHKCVDTLTGYYCDCNEGYKL-LA 3060
Query: 9778 DQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDG-YQLSSDDHSCKRTEMEPEPFFLL 9954
D K+C +V+EC E CSQ C + G + C C + Y+ +D+H+CKR + P P+ +
Sbjct: 3061 DGKACADVDECLEQPGACSQHCSNTPGGFYCKCDETYYERQNDEHTCKRKDKIP-PWLIF 3119
Query: 9955 ANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPL 10134
NK+Y+R +S+DG++Y L Q NVV+LD D+ E+ Y D + R E D +
Sbjct: 3120 TNKYYVRNMSVDGHQYNLMHQDLMNVVALDFDIREEYMYFCDVTAKTIFRAKYGEADDEM 3179
Query: 10135 -SSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKA 10311
E V+RH+ +G EGIA+DWVGRKLY L+R +++ V ELDG KTL R + P+A
Sbjct: 3180 PPEREAVIRHDSHGLEGIAIDWVGRKLYWLDRHSKNLDVSELDGSKRKTL-RSGVVDPRA 3238
Query: 10312 IVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLF 10491
IVVHPG GYL+FT W LQ YI ++ +DGS + + WPNA++IDYF+DR++
Sbjct: 3239 IVVHPGIGYLYFTSWHLQAYIAKMGMDGSNFSR---ILNWNDGIAWPNALSIDYFTDRIY 3295
Query: 10492 WGDAHLNEIGFMDFDGNGRRHI-PAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGK 10668
W DAHL+ I + D +G R + + HV ++ +FDDY+YW+DWNL+ ++R +K+ G
Sbjct: 3296 WADAHLDYIAYADLEGRHRHTVLSGSKVPHVFALSLFDDYIYWSDWNLKAIVRANKFHGA 3355
Query: 10669 NETILKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIG---------------A 10803
N T+L+ T P DL I HP+RQ Y NPCG NNGGCSHLCLI
Sbjct: 3356 NYTVLRNTTHRPYDLHINHPLRQLPYTNPCGTNNGGCSHLCLIAPPPESTYLNIEGYIEE 3415
Query: 10804 GGNGYTCSCPDQFVLLSDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEP 10983
G + C+CP+QF L D KTC NCT Q CGG D KCIP W CDGE DC+DGSDEP
Sbjct: 3416 GAPIFKCACPNQFYLARDMKTCVANCTAGQHLCGGRDEKCIPWFWKCDGEKDCKDGSDEP 3475
Query: 10984 GESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXXEQNCDKACDPWMFKCAATGR 11163
+ C R C G FQC N NCT I EQNCD C FKC ++GR
Sbjct: 3476 --ATCAPRHCRAGTFQCKNTNCTPSATICDGVDDCGDRSDEQNCDLPCPLSDFKCKSSGR 3533
Query: 11164 CIPRRFTXXXXXXXXXRSDEADTLCMSAERNCTAE-EFRCNNNKCIAKAWRXXXXXXXXX 11340
CI + SDE +C +R C + EF C N +CI + W
Sbjct: 3534 CILDSWRCDGDADCKDGSDEDPAVCF--KRTCDPKTEFSCKNGRCIPQLWMCDFDNDCGD 3591
Query: 11341 XXXETP-ECAQIECKKGWTRC--SSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVG 11511
E C Q C GW RC S+YRCIP W FC+G+DDCRDNSDE + CP C+
Sbjct: 3592 DSDEPAYMCRQRNCTTGWQRCPGQSNYRCIPKWLFCDGKDDCRDNSDELPENCPKCNPET 3651
Query: 11512 EFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVC 11691
+F+C + +CIP++WMCD +DCGD SDE +A C G R CSESEFRC +GKCI C
Sbjct: 3652 DFKCG-NNRCIPKQWMCDFADDCGDASDENEAVCKGRYRECSESEFRCGNGKCISSRWQC 3710
Query: 11692 DGTIQCSDGLDESQCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCED--VS 11865
D C D DE C +C G QC G CIA + CD +DC + +DE+ C
Sbjct: 3711 DHEDDCGDNSDEMHCEGYQCKNGTFQCASGHCIASYFRCDGDRDCRDMSDEVGCPPRFPG 3770
Query: 11866 RRTCSPFEFECANSVCIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCL 12045
R C F+C N++C+ + SDE S C CD RF+C++ R C+
Sbjct: 3771 GRYCPESRFQCNNNLCVSLSDLCDGTDDCGDGSDEDPSVCSDFNCDTLRRFQCSNER-CV 3829
Query: 12046 NILQLCNGFNDCGPNDFSDE-HLSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDC 12222
Q+C+G ++CG D SDE ++++C+S + D + Q++CAN C+ + CD DDC
Sbjct: 3830 ARYQICDGVDNCG--DGSDENNMTLCASKQKPCDLYT-QYQCANKHCIERSQVCDFSDDC 3886
Query: 12223 GDASDEIGCSKHGGKTSCEAFGNNGGCKHICTDVRDGFY-CHCRDGFRPDPQSPKECIDI 12399
GDASDE+GC H + EA N GGC+ C ++ DG Y C C G+ + K+C D+
Sbjct: 3887 GDASDELGC--HHTSSCSEA--NRGGCQQHCHNLTDGGYICTCYPGYIIAADNKKKCSDV 3942
Query: 12400 DEC-AGNNTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRA-KGDAANVMIGADDS 12573
DEC +TC+ C N G+Y C C E + + +G CRA K D + + +
Sbjct: 3943 DECLTRQHTCSHQCHNLNGTYSCSCREGFH---LTDGASGV-CRAEKEDVILLFVNGQE- 3997
Query: 12574 LVQLSLHGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERTIYRSAIANG--NQ 12747
+ G ++ ++++++W D ++TI RS + N +
Sbjct: 3998 -----IRGLNWHKSEEFAVIAAEKRIEALDYDAQQQIVFWADSYDKTIKRSYMVNAIDGR 4052
Query: 12748 SHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNT 12927
+ G D++ G PTA+AVD+ NL+ + T K R
Sbjct: 4053 AKIGFAQDLNMKG-GSKPTAVAVDWLASNLYWTEMDR-------TGSKPR---------- 4094
Query: 12928 GFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQII 13107
G + V DGRY + IV L+ PT++ P GRI +SDAG KIE + MDG+ R+ +
Sbjct: 4095 GRVMVAKTDGRYRRSIVNAGLEVPTSIAVNPQLGRIYWSDAGSAPKIEVSWMDGSKRRPL 4154
Query: 13108 VKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHD---RHIPYAVDVF 13278
+ +++ P + ID + + IYWVD K ++++ DGS R +V RH P ++D+F
Sbjct: 4155 ITEMIRHPAGLTIDYSQDHIIYWVDTKLNAIESMRADGSRRKAIVRGDQLRH-PVSLDLF 4213
Query: 13279 ENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQC 13458
E++++W++R++ L QDKFGRG VL + + ++V +T + C+ + C
Sbjct: 4214 ESNMFWMTRDTGELVRQDKFGRGVQVVLHRYIVNPSGLKVYHDKRYNTS-LPNPCDNSTC 4272
Query: 13459 SHLCVSLPSTGFACLCPDGIVP--------QLDGSCATQHVEALTMPKQCKCTNGGKCRL 13614
SHLC+ +P G C CPD P ++ + A +H P+ C C NGG C+
Sbjct: 4273 SHLCLLVPG-GHRCACPDASGPPPSHRSTAEVICNAAAEHPR--PAPRICPCQNGGLCKE 4329
Query: 13615 DGS----CECTSDFEGDQCEKESSVSRKIIGTLSENFITVXXXXXXXXXXXXXXXXXXXN 13782
D CEC + F G+ CE + +G V
Sbjct: 4330 DAQGELLCECRTQFVGEHCETST------MGAFGHGDANVTAVVVPIMVILLVMMAAAGA 4383
Query: 13783 LYKRRQLLFKK-----NEAADGSVSF-HGNVISFSNPVLENKQD------APGSEFNMQQ 13926
Y R+ F K + SV+F HG+ + F+ AP +N+Q
Sbjct: 4384 WYVIRKRPFGKLARMPAMTSSQSVTFRHGSNVEFNESGFPGASAPGAGDVAPIEGYNLQT 4443
Query: 13927 MTSMHDDSTTFTNPVYELEDVDMSSPPPSND---------QPSTSASAMSPNRPS--TSA 14073
+ + + + F NP+Y+ ++ P + +PS +M + T
Sbjct: 4444 VNA--NKARDFANPMYDAVQSGTTADPGMGNGSGIYDVPGEPSAKVKSMGHHAGGSFTEP 4501
Query: 14074 ASSFVPPTF----DQDEIELKTADEIIVPKAEISK 14166
AS+ + P+ +++L+T + + P A+ K
Sbjct: 4502 ASAIIAPSSITHKASPQLQLRTRE--LDPSADTGK 4534
Score = 385 bits (988), Expect = e-104
Identities = 295/1028 (28%), Positives = 457/1028 (43%), Gaps = 38/1028 (3%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXX-PHPGCKSDQWQCDTYTWHSVSCIA 333
C + F C +G+CI W C Q+ C T H CI
Sbjct: 1006 CGTSQFACANGRCIPNMWKCDSENDCGDSSDEGDFCAEKTCAYFQFTCPR-TGH---CIP 1061
Query: 334 EYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDE 513
+ CD DC D DEKDCP + C + N F CAD RQC + S KCDG DC D SDE
Sbjct: 1062 QSWVCDGDDDCFDKQDEKDCPP--ISCLA-NQFKCADLRQCVEESYKCDGIPDCNDGSDE 1118
Query: 514 KDSCSRNHTAC-FQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQC 690
S C + FRC CI +W CDGS DC+D SDE D C C N F+C
Sbjct: 1119 VGCPSMGPNQCNLEKHFRCKSTGFCIPIAWHCDGSNDCSDHSDEQD-CGQITCAQNFFKC 1177
Query: 691 KNKRCQPRKFRCDYYDDCGDNSD---EDEC--GEYRCPPGKWNCPGTG-HCIDQLKLCDG 852
N C + + CD DDCGDNSD E C ++CP G+W CPG C++ +CD
Sbjct: 1178 NNTNCVFKAYICDGKDDCGDNSDEGAEHACVPPPFKCPHGQWQCPGVSERCVNITSVCDD 1237
Query: 853 SKDCADGADE-QQCSQNLCPSLG--CQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINE 1023
+ DC +G+DE + C C C + C +P+G C CP G ++ + + TC D NE
Sbjct: 1238 TPDCPNGSDEGEGCDLAECEHQAGQCSSFCQKTPNGALCVCPPGSEIGEDGY-TCIDSNE 1296
Query: 1024 CAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVAR 1203
C G C Q C N + + CSC D + L+ P K C + N L ++
Sbjct: 1297 CDPPGLCSQQCTNTKGSYFCSCT-DGYVLE----PNKHT------CKAVNHTAAFLIISN 1345
Query: 1204 REGLYRLNPKNPD-EEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEIS 1380
R + + K E V + + G IFW+D D E +
Sbjct: 1346 RHSILVADLKEQGLERVPIIVENVVATASNMHTG--TIFWSDMKLKKISRLDRGMEPQ-- 1401
Query: 1381 QIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIA 1560
++ L LA DWI LY ++S I+VS+ +G R VL+ + +T P +
Sbjct: 1402 ---EIINTGLDLVEGLAYDWIAQNLYWLDSKLNTIEVSAENGSNRLVLVRENITQPRGMC 1458
Query: 1561 LDPLRGE--MFFTN---QLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPK 1725
+DP G +F+T+ ++E MDGT R+T++NT + +G+ +DI KRVY+ D K
Sbjct: 1459 IDPSPGARWIFWTDWGENPRVERIGMDGTMRKTIINTKIYWPNGLTLDIATKRVYFADSK 1518
Query: 1726 VDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLL 1905
+D ++ Y G R+ V + + HP L+LF+ LYWTD V+ KF + +
Sbjct: 1519 LDFIDFCYYNGTGRQQVLASSHYLLHPHSLSLFEDTLYWTDRQLNRVLSANKFRGKNQTV 1578
Query: 1906 WSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVGY 2085
S+ + P+ I +H QP NPC + C+ +C+LS GY
Sbjct: 1579 VSHLISQ--PLSIHVHHASLQP----------MTPNPCAGSRCQHLCLLSP---SAPEGY 1623
Query: 2086 KCACPIGQKLVNGKRCIDSIDYLLFSSNKIVRGI----FPEINEKALAEAVLPISPISQR 2253
C C G KL++ RCI+ + L +V+G P A A A+ P+ I +
Sbjct: 1624 SCKCRPGFKLLSEGRCIEEENPFLM----VVKGTQIVDLPLNGGDARAGALAPVIGI-ES 1678
Query: 2254 RIGMYFEVECDVHGNSFFYA----DIMDNTIYRIRPDGEGAAPVLVTHNDGL----FSMS 2409
G+ F D G + ++ D +N P G G + + +G+ ++++
Sbjct: 1679 STGLDF----DRKGETLYWVQGREDDDENCTIYTTPYGGGNKTLFLGIENGIVGAPYTIA 1734
Query: 2410 FDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKGLLFY 2589
FDW+ + LY + + +++E V++ L + P + + P +G LF+
Sbjct: 1735 FDWLGRNLYIGNRVASNIEAVRVDGKQKYRTIILANDGYPNSVSRPKQIALDPTEGKLFW 1794
Query: 2590 AE---AMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDF 2760
+ P I R ++GQN ++ P +A+D + + + + I MD+
Sbjct: 1795 IDEGVLEVPIKIGRVDMNGQN-PIVVFQEFAHPESLAVDTEKKMVYYSASNPAVIGVMDY 1853
Query: 2761 DGKN--VVKLDIDNPI--PVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADE 2928
+G + ++ + +P+ P ++ I++ +YY+ I R+ +G K + + +D
Sbjct: 1854 NGDDHTLILMKDSHPMAKPRSLGILDHRLYYLDPLYERIVRIDLPHGDNPKTIVDNESDL 1913
Query: 2929 RSIFSLKACSHQNQPIPDDSREHPCRASQ--CTQLCFATPSESHPNELEAKCACRQGFMI 3102
RS+ K + +HPC+ + C LC P + CAC G+
Sbjct: 1914 RSMMIYKKRA---------LMQHPCQTNNGGCKHLCIPGPGATR------TCACGIGY-- 1956
Query: 3103 NKENNHSC 3126
KEN +C
Sbjct: 1957 RKENEINC 1964
Score = 278 bits (710), Expect = 4e-72
Identities = 258/993 (25%), Positives = 400/993 (39%), Gaps = 55/993 (5%)
Frame = +1
Query: 3544 CGNATCAANQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQC 3723
C T A + + G C+P CDG DC G DE C V C QFRCANG +C
Sbjct: 26 CNTPTGAPAEGARLTGPCVPKEKRCDGYLDCRTGRDE--VGCSGVACRLDQFRCANGLKC 83
Query: 3724 VPLR---NHXXXXXXXXXXXXXXXXAVTAESCTPDQFKCVSSGLCIPASWKXXXXXXXXX 3894
+ NH C QF+C ++ LCIP ++
Sbjct: 84 IDAALKCNH-----RDDCGDNSDEQGCNFPPCHHAQFRC-TNALCIPYNFHCDGYHDCAD 137
Query: 3895 XSDEPKFGCTSGRQCSSDQFKC------GNGRCILNNWLCDGENDCGDGSDESSERGCKT 4056
SDE CT+ C ++ C G +CIL + LCDG+ DC DGSDE +T
Sbjct: 138 KSDEA--NCTA-IACPDNKHLCPRGGASGTPKCILKSQLCDGKRDCEDGSDE------ET 188
Query: 4057 SMNARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCSFKC 4236
+ + CP C FKC
Sbjct: 189 NCSIASCP--------------------------------------------ALSCEFKC 204
Query: 4237 HNSPNGPICSCPFGEQLV--NKTKCEPENECLDSSSCSQRCKDEKHGFTCSCDEGYELDV 4410
S G +C C G+ L N+T C +EC + C Q C + +TC C +GY L
Sbjct: 205 GPSLTGGVCYCKPGQSLAPDNRT-CVDLDECAEWGHCDQLCTNTLGSYTCQCAQGYTLIN 263
Query: 4411 DKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGA---IVENAIALA---WDSLTD 4572
D + C D +N I+ D + G+ I+ NA A A + +
Sbjct: 264 DSK-CIAPD--------ANNLQLIFAHDRAIMRMLPHGSEPKILANATAAAGVTFHYARN 314
Query: 4573 RIYWSDIREKKILSANRNGTNATVFIAD----GLDITEGIALDWVGRNLYWVDSSLNTIE 4740
+YWSDI+ +K+ S + N V D G +A+DWVG +Y D I+
Sbjct: 315 TLYWSDIKTRKVQSLPLDAQNKAVSPFDQTLPGTWAPVALAVDWVGDKIYVADLVGQKID 374
Query: 4741 VANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQNPCIERASMDGTDRQIIVKT 4920
V L + +++ N++ P +A+DP G+MF D GQ + RA MDGT + IV
Sbjct: 375 VFELSG-QWHAVVLGSNLTSPADLALDPTAGLMFVADGGQ---VLRAHMDGTHARSIVSE 430
Query: 4921 KIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFEDMM 5100
Y + + +D + RV++ DS LD+I+ V+Y+G+ R VL + V P LA+FE+ +
Sbjct: 431 AAYKASGVTVDIISKRVFWCDSLLDYIESVDYEGAHRVMVLRGQQ-VPSPSRLALFENRI 489
Query: 5101 YYSDRRLQKLQVYPKYPNGTTSE--YPSHTFSKALGVVAVHPVLQPVIKNNPCSTN--PC 5268
Y++D Q + K+ T+ + Y + + G++AVH + QP + +NPC N C
Sbjct: 490 YWTDATKQGIMSVDKFEGPTSIQVTYKAKDIREPKGIIAVHALSQPRV-SNPCGNNNGGC 548
Query: 5269 SHLCLLNNKN------TFTCKCPMGEKLDASGKKCIDDAKPFLVIIQ----KTNVFGIEM 5418
+H+C++ F C C G +L+ K C FL+ Q K V +
Sbjct: 549 NHMCIVTAVKGAPTGLGFRCACSTGYQLETDLKLC-KPVSEFLMYSQQRFIKGKVLEPVI 607
Query: 5419 NSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRST 5598
S+ PV++ GL +DA E ++ + IYR
Sbjct: 608 EGFSDAIMPVVSRRARFVGLD------FDARDEFIYYSD-----------VLQDVIYRVH 650
Query: 5599 VNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVILSNDQS 5778
NG + + +S + L DW +NL + T+ ++ T+ +R +L N
Sbjct: 651 RNGTGREIVLASQ-NEGVEGLAVDWASKNLYYIDSRKGTLNVLSTRNVTHRRTLLKN--- 706
Query: 5779 XXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAID 5958
+G++F+ + A + RA DGS LV + L + ++ID
Sbjct: 707 ---LKRPRAIVVHPNRGFIFFSE---WDRPANITRANTDGSGLLVFKNVTLGWPNGLSID 760
Query: 5959 TTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAFDS-IEV 6135
RVY+ +A + DG D V S R P + + D ++ D D+ I +
Sbjct: 761 FKEDRVYWCDALLDHVQHANLDGTDIKTVNSRLVRHPFSIVIHNDWMYITDWRLDAIIRL 820
Query: 6136 ATINGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHINNGNCDHICIPLMFA---- 6303
+ G+ + + + + + + + + PCH NNG C IC +
Sbjct: 821 HKLTGEQEEMMVREPQTNRLYGVKVYSHEVQRIADTQPCHRNNGGCQKICFAVPIGASNG 880
Query: 6304 --------------QRTCTCANG-YVKDGQTSC 6357
Q C+C G + D Q SC
Sbjct: 881 TDGVTTSSPSFGRLQSRCSCPYGERLADDQVSC 913
Score = 262 bits (670), Expect = 2e-67
Identities = 192/671 (28%), Positives = 301/671 (44%), Gaps = 23/671 (3%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAE 336
C+E++FRC +GKCI + W CK+ +QC S CIA
Sbjct: 3691 CSESEFRCGNGKCISSRWQCDHEDDCGDNSDEMHCEGYQCKNGTFQCA-----SGHCIAS 3745
Query: 337 YQRCDNITDCADGSDEKDCPASTVD--CSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSD 510
Y RCD DC D SDE CP ++ F C + C +S CDG DC D SD
Sbjct: 3746 YFRCDGDRDCRDMSDEVGCPPRFPGGRYCPESRFQC-NNNLCVSLSDLCDGTDDCGDGSD 3804
Query: 511 EKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPD----TCEFKKCTA- 675
E S + +F+C+++ +C+ + +CDG +C DGSDE + + K C
Sbjct: 3805 EDPSVCSDFNCDTLRRFQCSNE-RCVARYQICDGVDNCGDGSDENNMTLCASKQKPCDLY 3863
Query: 676 NEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGS 855
++QC NK C R CD+ DDCGD SDE C T C + +
Sbjct: 3864 TQYQCANKHCIERSQVCDFSDDCGDASDE------------LGCHHTSSCSEANR----- 3906
Query: 856 KDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGE-CTCPSGYKLDDRFHRTCSDINECAE 1032
GCQ CH GG CTC GY + + CSD++EC
Sbjct: 3907 -------------------GGCQQHCHNLTDGGYICTCYPGYIIAADNKKKCSDVDECLT 3947
Query: 1033 FGY-CDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARRE 1209
+ C C N ++CSC + G G C + D + LFV +E
Sbjct: 3948 RQHTCSHQCHNLNGTYSCSCREG---FHLTDGAS-------GVCRAEKEDVILLFVNGQE 3997
Query: 1210 GLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTD----RLAHSAFSADVDDEGEI 1377
+ LN + EE +A+ + I +D+D + +FW D + S +D +I
Sbjct: 3998 -IRGLN-WHKSEEFAVIAAEKRIEALDYDAQQQIVFWADSYDKTIKRSYMVNAIDGRAKI 4055
Query: 1378 SQIKKLSLKSLVYPRCLAVDWITNTLYIIE---SGSR---RIDVSSYDGERRTVLLADGL 1539
+ L++K P +AVDW+ + LY E +GS+ R+ V+ DG R ++ GL
Sbjct: 4056 GFAQDLNMKGGSKPTAVAVDWLASNLYWTEMDRTGSKPRGRVMVAKTDGRYRRSIVNAGL 4115
Query: 1540 TLPLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKR-V 1707
+P IA++P G ++++ + K+E + MDG+ RR L+ +G+ +D + +
Sbjct: 4116 EVPTSIAVNPQLGRIYWSDAGSAPKIEVSWMDGSKRRPLITEMIRHPAGLTIDYSQDHII 4175
Query: 1708 YWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFG 1887
YWVD K++ +ES+ G+ R+ + +G + + HP L LF+ ++W +++ +KFG
Sbjct: 4176 YWVDTKLNAIESMRADGSRRKAIVRG-DQLRHPVSLDLFESNMFWMTRDTGELVRQDKFG 4234
Query: 1888 SDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNG 2067
+++ N P G+ YH + + NPC N+ C +C+L
Sbjct: 4235 RGVQVVLHRYIVN--PSGLKVYH---------DKRYNTSLPNPCDNSTCSHLCLLVPG-- 4281
Query: 2068 GFGVGYKCACP 2100
G++CACP
Sbjct: 4282 ----GHRCACP 4288
Score = 186 bits (471), Expect = 2e-44
Identities = 171/691 (24%), Positives = 265/691 (37%), Gaps = 13/691 (1%)
Frame = +1
Query: 8842 KADENQLFCMNQQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICV 9021
K LFC A +G C+P+ +CDG DC G DE C+ A C
Sbjct: 18 KCQHTDLFCNTPTGAPAEGARLTGPCVPKEKRCDGYLDCRTGRDE--VGCSGVA----CR 71
Query: 9022 GDYLFQCDN-LKCISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPK 9198
D F+C N LKCI A GC C +F CT+
Sbjct: 72 LDQ-FRCANGLKCIDAAL---KCNHRDDCGDNSDEQGCNFPPCHHAQFRCTNAL------ 121
Query: 9199 YECIPRAWLCDGDVTCAGGEDE---STELCKTEKKECNKGEFRCSNQHCIHSTWECDGDN 9369
CIP + CDG CA DE + C K C +G CI + CDG
Sbjct: 122 --CIPYNFHCDGYHDCADKSDEANCTAIACPDNKHLCPRGG-ASGTPKCILKSQLCDGKR 178
Query: 9370 DCLDGSDEHANCTYSSCQPDFFQCANHKCVPNSWKCDGNDDCEDGSDEKDCPKNSASAQK 9549
DC DGSDE NC+ +SC C KC P+
Sbjct: 179 DCEDGSDEETNCSIASCPA--LSC-EFKCGPS---------------------------- 207
Query: 9550 ASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCMDMK 9729
+ G C G+ + N C D +DEC AE C+Q C +
Sbjct: 208 ---LTGGVCYCKPGQ-----SLAPDNRTCVD---------LDEC--AEWGHCDQLCTNTL 248
Query: 9730 IGYKCDCFEGFAIDISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDH 9909
Y C C +G+ + I KC D L
Sbjct: 249 GSYTCQCAQGYTL----------------------------INDSKCIAPDANNLQ---- 276
Query: 9910 SCKRTEMEPEPFFLLANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLIDQGK 10089
+ A+ I ++ G++ ++ A + Y D
Sbjct: 277 ------------LIFAHDRAIMRMLPHGSEPKILANA-TAAAGVTFHYARNTLYWSDIKT 323
Query: 10090 LRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRF 10269
++ + LD + +S ++ L + +AVDWVG K+Y+ + + I V EL G++
Sbjct: 324 RKVQSLPLDAQNKAVSPFDQTL-PGTWAPVALAVDWVGDKIYVADLVGQKIDVFELSGQW 382
Query: 10270 CKTLIRDRIQQPKAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGW 10449
++ + P + + P G +F + + R +DG+ + + + A G
Sbjct: 383 HAVVLGSNLTSPADLALDPTAGLMFVADGG---QVLRAHMDGT-HARSIVSEAAYKASG- 437
Query: 10450 PNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGR-RHIPAQRTSHVSSMVVFDDYLYWADW 10626
+ +D S R+FW D+ L+ I +D++G R + Q+ S + +F++ +YW D
Sbjct: 438 ---VTVDIISKRVFWCDSLLDYIESVDYEGAHRVMVLRGQQVPSPSRLALFENRIYWTDA 494
Query: 10627 NLREVLRCDKWTGKNE---TILKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLI 10797
+ ++ DK+ G T K ++ P + VH + QP NPCG+NNGGC+H+C++
Sbjct: 495 TKQGIMSVDKFEGPTSIQVTYKAKDIREPKGIIAVHALSQPRVSNPCGNNNGGCNHMCIV 554
Query: 10798 GA-----GGNGYTCSCPDQFVLLSDQKTCEP 10875
A G G+ C+C + L +D K C+P
Sbjct: 555 TAVKGAPTGLGFRCACSTGYQLETDLKLCKP 585
Score = 177 bits (449), Expect = 7e-42
Identities = 163/671 (24%), Positives = 263/671 (38%), Gaps = 35/671 (5%)
Frame = +1
Query: 11626 RPCSESEFRCND------------GKCIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQ 11769
R C ++ CN G C+P K CDG + C G DE C+ C +
Sbjct: 17 RKCQHTDLFCNTPTGAPAEGARLTGPCVPKEKRCDGYLDCRTGRDEVGCSGVACRLDQFR 76
Query: 11770 CDDG-TCIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFECANSVCIPRKFMXXXXX 11946
C +G CI C+ + DC + +DE C + C +F C N++CIP F
Sbjct: 77 CANGLKCIDAALKCNHRDDCGDNSDEQGC---NFPPCHHAQFRCTNALCIPYNFH----- 128
Query: 11947 XXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSS 12126
C+G++DC D SDE + C++
Sbjct: 129 --------------------------------------CDGYHDCA--DKSDE--ANCTA 146
Query: 12127 FSEYGDCSSDQFKCANG------KCVNGTVACDRKDDCGDASD-EIGCSKHGGKTSCEAF 12285
+ C ++ C G KC+ + CD K DC D SD E CS SC A
Sbjct: 147 IA----CPDNKHLCPRGGASGTPKCILKSQLCDGKRDCEDGSDEETNCS----IASCPAL 198
Query: 12286 GNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGSYLC 12465
C+ C G C+C+ G P + + C+D+DECA C QLC NT GSY C
Sbjct: 199 ----SCEFKCGPSLTGGVCYCKPGQSLAPDN-RTCVDLDECAEWGHCDQLCTNTLGSYTC 253
Query: 12466 RCHEDYENNVVVGSMTGKDCRAKGDAANVMI--GADDSLVQLSLHGSGTNRHXXXXXXXX 12639
+C + Y + C A DA N+ + D +++++ HGS
Sbjct: 254 QCAQGYT------LINDSKCIAP-DANNLQLIFAHDRAIMRMLPHGSEPK------ILAN 300
Query: 12640 XXXXXXXXXXPRKELMYWIDGSERTIYRSAIANGNQ--SHEGQKLDVDFAAMGVVPTAIA 12813
+ +YW D R + + N+ S Q L +A P A+A
Sbjct: 301 ATAAAGVTFHYARNTLYWSDIKTRKVQSLPLDAQNKAVSPFDQTLPGTWA-----PVALA 355
Query: 12814 VDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQ 12993
VD+ +++A + + + ID V G++ ++ +L
Sbjct: 356 VDWVGDKIYVADL---------------VGQKID--------VFELSGQWHAVVLGSNLT 392
Query: 12994 QPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIY 13173
P L P+AG + +D G ++ A MDGTH + IV + + + + +D R++
Sbjct: 393 SPADLALDPTAGLMFVADGG---QVLRAHMDGTHARSIVSEAAYKASGVTVDI-ISKRVF 448
Query: 13174 WVDPKYRRVDAVNIDGSERTTVVHDRHI--PYAVDVFENHIYWLSRESKTLYVQDKFGRG 13347
W D +++V+ +G+ R V+ + + P + +FEN IYW + + DKF
Sbjct: 449 WCDSLLDYIESVDYEGAHRVMVLRGQQVPSPSRLALFENRIYWTDATKQGIMSVDKFEGP 508
Query: 13348 ---RVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCV------SLPSTGFAC 13500
+V+ A D+ + + ++ G C+H+C+ + GF C
Sbjct: 509 TSIQVTYKAKDIREPKGIIAVHALSQPRVSNPCGNNNGGCNHMCIVTAVKGAPTGLGFRC 568
Query: 13501 LCPDGIVPQLD 13533
C G + D
Sbjct: 569 ACSTGYQLETD 579
Score = 151 bits (381), Expect = 5e-34
Identities = 105/344 (30%), Positives = 146/344 (41%), Gaps = 26/344 (7%)
Frame = +1
Query: 148 SSVCNENDFRCNDGKCIRTEWX--XXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSV 321
++ C + F C +G+CI W + C ++++C ++
Sbjct: 2601 NNTCEASKFYCKNGRCISRMWSCDGDDDCGDNSDEDPNYCAYHSCSPNEFRC-----NNG 2655
Query: 322 SCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRD 501
CI + +CD+ DC DGSDE C F CA+GR C ++ C+G DC+D
Sbjct: 2656 RCIFKSWKCDHENDCKDGSDELGC---VYPPCVDGEFTCANGR-CIPQAQVCNGVNDCKD 2711
Query: 502 --LSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDE-PDTCEFKKCT 672
SDE +T C +C C++ W+CDG DC D SDE P C + C
Sbjct: 2712 NATSDETHERCPMNTTCPANHLKCEKTNICVEPYWLCDGDNDCGDNSDEDPLHCGQRTCP 2771
Query: 673 ANEFQCKNKRCQPRKFRCDYYDDCGDNSDE--DEC-GEYRCPPGKWNCPGTGHCIDQLKL 843
N F+C N RC P + CD DDCGD +DE D C E R G G+CI ++ +
Sbjct: 2772 TNSFRCPNHRCIPATWYCDGDDDCGDGADEPPDYCKSEGRTCFGDLFTCDNGNCIPRIYI 2831
Query: 844 CDGSKDCADGADE---QQCSQNLC---PSLGC-------QAGCHPSPH--GGECTCPSGY 978
CDG DC D +DE QC+ C C +A C P G+ C G
Sbjct: 2832 CDGDNDCLDNSDEDNRHQCNDRKCDEETEFTCVENKSWQRAQCIPKKWICDGDPDCVDGA 2891
Query: 979 KLDDRFHRTCSDINECAEFGYCDQLCANHR---PGFTCSCLGDC 1101
+ H C+ C E + C N R G+ C DC
Sbjct: 2892 DENTTLH-NCATQQPCGEDMF---TCGNGRCINKGWICDHDNDC 2931
Score = 151 bits (381), Expect = 5e-34
Identities = 120/384 (31%), Positives = 162/384 (41%), Gaps = 45/384 (11%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAE 336
C+ N+FRCN+G+CI W +P C ++ C + CI +
Sbjct: 2645 CSPNEFRCNNGRCIFKSWKCDHENDCKDGSDELGCVYPPCVDGEFTC-----ANGRCIPQ 2699
Query: 337 YQRCDNITDCADG--SDE--KDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDL 504
Q C+ + DC D SDE + CP +T C + N C C + CDG DC D
Sbjct: 2700 AQVCNGVNDCKDNATSDETHERCPMNTT-CPA-NHLKCEKTNICVEPYWLCDGDNDCGDN 2757
Query: 505 SDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDE-PDTC--EFKKCTA 675
SDE D C FRC + +CI +W CDG DC DG+DE PD C E + C
Sbjct: 2758 SDE-DPLHCGQRTCPTNSFRCPNH-RCIPATWYCDGDDDCGDGADEPPDYCKSEGRTCFG 2815
Query: 676 NEFQCKNKRCQPRKFRCDYYDDCGDNSDED---ECGEYRC-PPGKWNCPGT-----GHCI 828
+ F C N C PR + CD +DC DNSDED +C + +C ++ C CI
Sbjct: 2816 DLFTCDNGNCIPRIYICDGDNDCLDNSDEDNRHQCNDRKCDEETEFTCVENKSWQRAQCI 2875
Query: 829 DQLKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGE--CTCPSGYKLDDRFHR 1002
+ +CDG DC DGADE N C GE TC +G ++ +
Sbjct: 2876 PKKWICDGDPDCVDGADENTTLHNCATQQPC----------GEDMFTCGNGRCINKGW-- 2923
Query: 1003 TCSDINECA----EFGYCD---QLCANHRPGFTCS----------CLG--DCFTLQMEHG 1125
C N+C E +C+ + C+ FTC C G DC E G
Sbjct: 2924 ICDHDNDCGDGTDEGKFCNSKYKTCSAQE--FTCQNFKCIRNQSRCDGEDDCGDHSDEVG 2981
Query: 1126 PGKDNLT--------MRGYCVSNN 1173
K+N+T G C+ N
Sbjct: 2982 CAKENITCPQGQFACTNGQCIDYN 3005
Score = 150 bits (380), Expect = 7e-34
Identities = 107/341 (31%), Positives = 142/341 (41%), Gaps = 75/341 (21%)
Frame = +1
Query: 271 GCKSDQWQCDT-------YTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNV 429
G +SD+ CD S CI + RCD DC DGSDE C +
Sbjct: 3509 GDRSDEQNCDLPCPLSDFKCKSSGRCILDSWRCDGDADCKDGSDEDPAVCFKRTCDPKTE 3568
Query: 430 FMCADGR------------QCFDVSKK-------------------------------CD 480
F C +GR C D S + CD
Sbjct: 3569 FSCKNGRCIPQLWMCDFDNDCGDDSDEPAYMCRQRNCTTGWQRCPGQSNYRCIPKWLFCD 3628
Query: 481 GKYDCRDLSDE-KDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTC- 654
GK DCRD SDE ++C + + + F+C + +CI K W+CD + DC D SDE +
Sbjct: 3629 GKDDCRDNSDELPENCPKCNP---ETDFKCGN-NRCIPKQWMCDFADDCGDASDENEAVC 3684
Query: 655 --EFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCI 828
+++C+ +EF+C N +C +++CD+ DDCGDNSDE C Y+C G + C +GHCI
Sbjct: 3685 KGRYRECSESEFRCGNGKCISSRWQCDHEDDCGDNSDEMHCEGYQCKNGTFQC-ASGHCI 3743
Query: 829 DQLKLCDGSKDCADGADEQ-----------------QCSQNLCPSLGCQAGCHPSPHGGE 957
CDG +DC D +DE QC+ NLC SL G
Sbjct: 3744 ASYFRCDGDRDCRDMSDEVGCPPRFPGGRYCPESRFQCNNNLCVSLSDLC-------DGT 3796
Query: 958 CTCPSGYKLDDRFHRTCSDINECAEFGYCDQL----CANHR 1068
C G D CSD N CD L C+N R
Sbjct: 3797 DDCGDG---SDEDPSVCSDFN-------CDTLRRFQCSNER 3827
Score = 135 bits (339), Expect = 4e-29
Identities = 114/429 (26%), Positives = 160/429 (36%), Gaps = 67/429 (15%)
Frame = +1
Query: 124 ISASVNTASSVCNENDFRCN--DGKCIRTEWXXXXXXXXXXXXXXXXXPHPG-CKSDQWQ 294
++ + T + C C D KCI W P C++ +Q
Sbjct: 3430 LARDMKTCVANCTAGQHLCGGRDEKCIPWFWKCDGEKDCKDGSDEPATCAPRHCRAGTFQ 3489
Query: 295 CDTYTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKK 474
C + +C CD + DC D SDE++C + C + F C +C S +
Sbjct: 3490 CK-----NTNCTPSATICDGVDDCGDRSDEQNC---DLPCPLSD-FKCKSSGRCILDSWR 3540
Query: 475 CDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPD-T 651
CDG DC+D SDE + T + +F C + +CI + W+CD DC D SDEP
Sbjct: 3541 CDGDADCKDGSDEDPAVCFKRTCDPKTEFSCKN-GRCIPQLWMCDFDNDCGDDSDEPAYM 3599
Query: 652 CEFKKCTA-------------------------------------------NEFQCKNKR 702
C + CT +F+C N R
Sbjct: 3600 CRQRNCTTGWQRCPGQSNYRCIPKWLFCDGKDDCRDNSDELPENCPKCNPETDFKCGNNR 3659
Query: 703 CQPRKFRCDYYDDCGDNSDEDEC---GEYR-CPPGKWNCPGTGHCIDQLKLCDGSKDCAD 870
C P+++ CD+ DDCGD SDE+E G YR C ++ C G G CI CD DC D
Sbjct: 3660 CIPKQWMCDFADDCGDASDENEAVCKGRYRECSESEFRC-GNGKCISSRWQCDHEDDCGD 3718
Query: 871 GADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFH----RTCSDINECAEFG 1038
+DE C C + G C SG+ + F R C D+++ E G
Sbjct: 3719 NSDEMHCEGYQCKN-------------GTFQCASGHCIASYFRCDGDRDCRDMSD--EVG 3763
Query: 1039 ---------YCDQ---LCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADK 1182
YC + C N+ C L D + G G D C N D
Sbjct: 3764 CPPRFPGGRYCPESRFQCNNN----LCVSLSDLCDGTDDCGDGSDE--DPSVCSDFNCDT 3817
Query: 1183 MKLFVARRE 1209
++ F E
Sbjct: 3818 LRRFQCSNE 3826
Score = 105 bits (262), Expect = 3e-20
Identities = 76/224 (33%), Positives = 98/224 (42%), Gaps = 20/224 (8%)
Frame = +1
Query: 8407 GSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTN-RRCIDSAKKCNHIDDCGD 8583
G C+ CD DC DE C+ +C D C N +CID+A KCNH DDCGD
Sbjct: 41 GPCVPKEKRCDGYLDCRTGRDEVG--CSGVACRLDQFRCANGLKCIDAALKCNHRDDCGD 98
Query: 8584 GSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPGLPIDCRG 8763
SDE C + C F C+N CI CDG++DC D+ SDE+ T I C
Sbjct: 99 NSDEQGC-NFPPCHHAQFRCTNALCIPYNFHCDGYHDCADK--SDEANCTA----IACPD 151
Query: 8764 VKVRCP-----NTNICIQPADLCDGYDDCGDKADENQLFCMNQQC-------------AQ 8889
K CP T CI + LCDG DC D +DE + C C
Sbjct: 152 NKHLCPRGGASGTPKCILKSQLCDGKRDCEDGSDE-ETNCSIASCPALSCEFKCGPSLTG 210
Query: 8890 HYVRCPSGRCI-PETWQCDGDNDCSDGWDETHTNCTDTAGKKIC 9018
C G+ + P+ C ++C++ W CT+T G C
Sbjct: 211 GVCYCKPGQSLAPDNRTCVDLDECAE-WGHCDQLCTNTLGSYTC 253
Score = 87.4 bits (215), Expect = 9e-15
Identities = 77/258 (29%), Positives = 95/258 (35%), Gaps = 1/258 (0%)
Frame = +1
Query: 8551 KKCNHIDDCGDGSDELDCPSAV-ACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESL 8727
+KC H D L C + A AEG G C+ + K CDG+ DC + DE
Sbjct: 17 RKCQHTD--------LFCNTPTGAPAEGAR--LTGPCVPKEKRCDGYLDCRTGR--DE-- 62
Query: 8728 ATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCP 8907
C G + CR + RC N CI A C+ DDCGD +DE C C RC
Sbjct: 63 VGCSG--VACRLDQFRCANGLKCIDAALKCNHRDDCGDNSDEQG--CNFPPCHHAQFRCT 118
Query: 8908 SGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXX 9087
+ CIP + CDG +DC+D DE NCT A
Sbjct: 119 NALCIPYNFHCDGYHDCADKSDE--ANCTAIA---------------------------- 148
Query: 9088 XXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDES 9267
C D + C PK CI ++ LCDG C G DE
Sbjct: 149 -------------------CPDNKHLCPRGGASGTPK--CILKSQLCDGKRDCEDGSDEE 187
Query: 9268 TELCKTEKKECNKGEFRC 9321
T C EF+C
Sbjct: 188 TN-CSIASCPALSCEFKC 204
Score = 74.3 bits (181), Expect = 8e-11
Identities = 62/216 (28%), Positives = 81/216 (36%), Gaps = 6/216 (2%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDT--YTWHSVSCI 330
C E+ F C +G+CI W C S C +T + CI
Sbjct: 2906 CGEDMFTCGNGRCINKGWICDHDNDCGDGTDEGKF----CNSKYKTCSAQEFTCQNFKCI 2961
Query: 331 AEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSD 510
RCD DC D SDE C + C Q F C +G QC D + C+ DC D SD
Sbjct: 2962 RNQSRCDGEDDCGDHSDEVGCAKENITC-PQGQFACTNG-QCIDYNLVCNKYPDCADESD 3019
Query: 511 EKDSCSRNHTACFQYQFRCADKTQCIQKSWVCD---GSKDCADGSDEPDTCE-FKKCTAN 678
E C+ + A + +C K + CD G K ADG D E ++ A
Sbjct: 3020 EPAHCNVDECAKVEIN-QCGHKCVDTLTGYYCDCNEGYKLLADGKACADVDECLEQPGAC 3078
Query: 679 EFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRC 786
C N P F C C + E + E+ C
Sbjct: 3079 SQHCSN---TPGGFYC----KCDETYYERQNDEHTC 3107
Score = 70.1 bits (170), Expect = 2e-09
Identities = 54/184 (29%), Positives = 68/184 (36%), Gaps = 14/184 (7%)
Frame = +1
Query: 3196 GRCIPKEWKCDGENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKKCIPAQXXXXXXX 3375
G C+PKE +CDG DC DE+ G C + +C N KCI A
Sbjct: 41 GPCVPKEKRCDGYLDCRTGRDEVGCSG------VACRLDQFRCANGLKCIDAALKCNHRD 94
Query: 3376 XXXXXXXXXVKYCKDGQK------PVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKL 3537
C D P C +F+C N CIP + E
Sbjct: 95 D-----------CGDNSDEQGCNFPPCHHAQFRCTNALCIPYNFHCDGYHDCADKSDE-- 141
Query: 3538 EMCGNATCAANQFSCANG------RCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSAL-- 3693
C C N+ C G +CI LCDG DC DG+DE+ C C AL
Sbjct: 142 ANCTAIACPDNKHLCPRGGASGTPKCILKSQLCDGKRDCEDGSDEE-TNCSIASCPALSC 200
Query: 3694 QFRC 3705
+F+C
Sbjct: 201 EFKC 204
Score = 65.1 bits (157), Expect = 5e-08
Identities = 46/150 (30%), Positives = 61/150 (40%), Gaps = 6/150 (4%)
Frame = +1
Query: 136 VNTASSVCNENDFRCNDG-KCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTW 312
V + C + FRC +G KCI P C Q++C
Sbjct: 63 VGCSGVACRLDQFRCANGLKCIDAALKCNHRDDCGDNSDEQGCNFPPCHHAQFRCT---- 118
Query: 313 HSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGR-----QCFDVSKKC 477
+ CI CD DCAD SDE +C A + C N +C G +C S+ C
Sbjct: 119 -NALCIPYNFHCDGYHDCADKSDEANCTA--IACPD-NKHLCPRGGASGTPKCILKSQLC 174
Query: 478 DGKYDCRDLSDEKDSCSRNHTACFQYQFRC 567
DGK DC D SDE+ +CS +F+C
Sbjct: 175 DGKRDCEDGSDEETNCSIASCPALSCEFKC 204
>gi|50750481|ref|XP_422014.1| PREDICTED: similar to glycoprotein
receptor gp330/megalin precursor [Gallus gallus]
Length = 4742
Score = 2672 bits (6926), Expect = 0.0
Identities = 1605/4672 (34%), Positives = 2348/4672 (49%), Gaps = 170/4672 (3%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDT----------- 303
C FRC +G+CI +W P P C+ +Q+QC T
Sbjct: 33 CGGGQFRCGNGRCIPADWRCDGARDCSDDTDEAGCPQPTCEGNQFQCQTDGECIPHSWVC 92
Query: 304 -------------------------YTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTV 408
+T + CI RCD + DC DG+DE+DC
Sbjct: 93 DDEEDCEDGSDEHQQCPGRTCSSQQFTCSNGQCIPSAYRCDRVKDCTDGTDERDCRYPRC 152
Query: 409 DCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCI 588
+ S CA+G CF+ S++CDGK DCRD SDE + C+R C QF+CA+ +CI
Sbjct: 153 EQLS-----CANGA-CFNASQRCDGKVDCRDTSDEAN-CTRG---CASTQFQCANG-ECI 201
Query: 589 QKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDE 768
++++CD DC D SDE ++C + C N F C + RC + + CD DDC DN DE
Sbjct: 202 PQAFMCDHDDDCGDRSDE-NSCTYATCRGNFFTCPSGRCIHQSWICDGDDDCEDNEDERG 260
Query: 769 CGE--YRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADE------QQCSQNLCPSLGCQ 924
C + C PG+W CP +GHCI K+CDG+ DC G DE + C+ + C +L CQ
Sbjct: 261 CESSYHECYPGEWACPESGHCIPIGKVCDGAADCPAGEDETNITAGRHCNISHCAALSCQ 320
Query: 925 AGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCF 1104
CH SP GG C CPSGY + RTC D ++C +G CDQLC + C C+ F
Sbjct: 321 YRCHSSPSGGMCYCPSGYTISSNDSRTCIDFDDCKMWGVCDQLCEDRVGHHQCHCVEGYF 380
Query: 1105 TLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKLASGEFIYG 1284
H + + SN D + + L+ +N V+ G + G
Sbjct: 381 LEHHRHCRANTSAGVASIIFSNGRDLL---------IGDLHGRNFRTLVQSQNRGVAV-G 430
Query: 1285 IDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYII 1464
+DF + +IFWTD + FS ++D + ++ +S+ + P LAVDW+ N LY++
Sbjct: 431 VDFHFYLHRIFWTDTVQDKVFSINIDGS-DFQEVLNVSVDT---PENLAVDWVNNKLYVV 486
Query: 1465 ESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTN------QLKLEAAAMD 1626
E+ RID+ + DG R L+A+ L P IALDP G +FF++ K+E A MD
Sbjct: 487 ETSVNRIDMVNLDGTNRVTLIAENLGNPRGIALDPTVGYLFFSDWDSLSGDPKVERAFMD 546
Query: 1627 GTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHP 1806
GTNR+ L+ T +GI +DI +KR+YWVD + D +E++ Y G RR +A G +++PHP
Sbjct: 547 GTNRQDLIKTKLGWPAGITLDIVSKRLYWVDSRFDYIETVTYDGLQRRTIAHGGSLIPHP 606
Query: 1807 FGLALFDQYLYWTDWTRLGVIQVEKFG-SDTKLLWSNTENNVFPMGISAYHPMAQPGPGQ 1983
+G+ LF+ +Y+TDWT++ V++ KF S+ ++++ ++++ P G++ YH QP
Sbjct: 607 YGITLFEHNVYFTDWTKMAVVKANKFSESNPQVIY---QSSLRPYGVTVYHAARQP---- 659
Query: 1984 SECLAMKIENPC--TNADCEGMCILSKDNGGFGVGYKCACPIGQKL-VNGKRCIDSIDYL 2154
+ NPC N CE +C+LS G+GY+C C +G L V+G+ C+ +L
Sbjct: 660 ------YVRNPCGNNNGGCEQICVLSHKTDNDGLGYRCRCILGFDLHVDGRHCVAVQQFL 713
Query: 2155 LFSSNKIVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTI 2334
LFSS VRGI N + ++P++ +G+ F + D + F++D + I
Sbjct: 714 LFSSQLAVRGI--PFNLSTQEDVIIPVTGSPSYFVGIDFWAQDD----TIFFSDTSRDMI 767
Query: 2335 YRIRPDGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELV 2514
Y+ + DG G + + + ++FDWISK LY+ D S+ V+++ +
Sbjct: 768 YKQKTDGSGREILTANRVESVEDLAFDWISKNLYWTDPRYRSISVMRLADKS-------- 819
Query: 2515 RRQLITELRDPVSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAI 2694
RR ++ L +P S+VVHP G +F+ + RPA I R DG + I NTTLG P+ +AI
Sbjct: 820 RRAIVQNLNNPRSIVVHPVIGYIFWTDWFRPAKIMRAWSDGSHGLPIVNTTLGWPNGLAI 879
Query: 2695 DFAENRLCWGDTLLKTISCMDFDG--KNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIR 2868
D++ RL W D I FDG + ++ P +TI Y Y+ R +I
Sbjct: 880 DWSSLRLYWVDAFFDKIEHSTFDGLDRRTLERVAQMTHPFGLTIFGGYAYFTDWRLGAIV 939
Query: 2869 RVHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSE 3048
RV K +GG I+R +I +KA +Q + C+ CF P+
Sbjct: 940 RVRKSDGGEMTIIRR---GISNIMHVKAYDAHSQIGSNYCNRGTNPNGDCSHFCFPVPN- 995
Query: 3049 SHPNELEAKCACRQGFMINKENNHSCQKDPAEKIEQL-CSSNSTQFQCKNGRCIPKEWKC 3225
+ C C G + N +C +DP+ + L C S S F C NGRC+P+ ++C
Sbjct: 996 -----FQRVCGCPYGMKLGS-NQLTCVEDPSNEPPTLQCGSYS--FSCNNGRCVPRYYQC 1047
Query: 3226 DGENDCLDESDEIDEKGDKCFH-ETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXX 3402
DG +DC D SDE C C+ + C N + CIP++
Sbjct: 1048 DGIDDCHDNSDE-----QNCGSLNNTCSSSAFTCANGQ-CIPSRWRCDKHNDCFDGSDEL 1101
Query: 3403 VKYCKDGQKPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNATCAANQFSC 3582
C C F CDN+RCIP W EK TC QF C
Sbjct: 1102 --RCPTQGPTSCPETLFTCDNNRCIPRIWLCDTDNDCGDGSDEK-NCTFTGTCEPRQFQC 1158
Query: 3583 ANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQCVPLRNHXXXXXXX 3762
+ RCI Y++CDGD DC DG DE C CS +F+C +G QC+
Sbjct: 1159 PDHRCIDPYYVCDGDKDCVDGADEHD--CI-YNCSGTEFKCVSGDQCISSYYQCDGVFDC 1215
Query: 3763 XXXXXXXXXAVTAES-CTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQC 3939
C ++F+C S G CIPA+W+ SDE C + R C
Sbjct: 1216 NDHSDETDCPTRPPGMCHQNEFQCQSDGNCIPANWECDGHLDCADGSDE-HHRCPA-RTC 1273
Query: 3940 SSDQFKCGNGRCILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETC 4119
F+C NG C+ W+CDG+NDC D SDE R C T +CP C C
Sbjct: 1274 PPSLFRCDNGNCVYRAWICDGDNDCRDMSDE---RDCPTQ--PFRCPSWQWQCPG-HSIC 1327
Query: 4120 IPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCSFKCHNSPNGPICSCPFGEQLVNKT 4299
+ L ++CD CP G DE C ++ CS + AGC+ +C P G C+CP G QL N +
Sbjct: 1328 VNLSKVCDNSADCPNGADESPLCNQESCSDNNAGCTHECIQGPFGAQCTCPVGYQLTNDS 1387
Query: 4300 K-CEPENECLDSSSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRN 4476
K CE NEC CSQ C +E+ F C CDEGY L+ + RTCKVA++ + + V++RN
Sbjct: 1388 KTCEDINECDPPGFCSQHCYNERGSFRCYCDEGYILETNGRTCKVAES-GNLLLLVASRN 1446
Query: 4477 RIYYSDHKLDNWHTFGAIVE---NAIALAWDSLTDRIYWSDIREKKILSANRNGTNATVF 4647
+I D+ H+ +++ N +A+ +DS++DRI+WSD + KI SA +NGT+ V
Sbjct: 1447 QIVV-DNITSQSHSIYSLIRDGRNIVAIDFDSISDRIFWSDTTQDKIWSAYQNGTDRKVV 1505
Query: 4648 IADGLDITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPR 4827
G+ +TE IA+DWVGRNLYW D L TIEV+ + D RT+L+ +NV+ PRG+ +DPR
Sbjct: 1506 FDSGVTVTESIAVDWVGRNLYWTDFVLETIEVSKM-DGSHRTVLISENVTNPRGLVLDPR 1564
Query: 4828 --KGVMFWTDWGQNPCIERASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFI 5001
VMFWTDWGQNP IE+ASMDG R +I+ +KIYWPN +++DY +YFAD+ LD+I
Sbjct: 1565 IDAHVMFWTDWGQNPRIEKASMDGKLRTVIISSKIYWPNGLSIDYPNKLLYFADAYLDYI 1624
Query: 5002 DFVNYDGSGRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNG--TTSEYP 5175
DF +Y+G+ R QV+AS +QHPH L IFED +Y+SDR ++ K+ G T Y
Sbjct: 1625 DFCDYNGNNRRQVVASDLVLQHPHGLTIFEDFVYWSDRYTNRVIRANKWHGGNQTVMIYN 1684
Query: 5176 SHTFSKALGVVAVHPVLQPVIKNNPCSTNPCSHLCLLNNKNT--FTCKCPMGEKLDASGK 5349
H + LG+VAVHPV QP N+ C+++PCSHLCLL++ F+C CP G L +
Sbjct: 1685 IH---QPLGLVAVHPVKQPYGINS-CASSPCSHLCLLSSSGPLFFSCACPSGWMLSPDNR 1740
Query: 5350 KCIDDAKPFLVIIQKTNVFGIEMNSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFI 5529
C+ PFL+ ++ ++GI +N + MVP++G+ N D +D + ++
Sbjct: 1741 NCMRVEHPFLIAVRDNIIYGISLNPEEKTND----AMVPIAGVQNGVDVDFDDSEQMIYW 1796
Query: 5530 LEHTNHAKTLAQITTDSAIYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKIT 5709
+E+ I+R +G N+T +AV L DW NL N T
Sbjct: 1797 VENPGE------------IHRVRSDGSNRTVFAPAAVIGAPIGLALDWISANLYYSNPGT 1844
Query: 5710 QTIEIIRTQGK-QYRSVILSNDQSXXXXXXXXXXXXXXXKGYVFWLDRG-GGAADAKVAR 5883
Q+IE+++ G+ YR +++ND + +G ++W D+G AKVA
Sbjct: 1845 QSIEVLKLHGEVMYRKTLITNDGTSLGAGTPIGLTVDPARGKLYWTDQGTDSGVPAKVAS 1904
Query: 5884 AGLDGSNPLVIASNDLAELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGR 6063
A +DGS + + +L ++ I ID ++Y++ G I DG +R L
Sbjct: 1905 ANMDGSGIQTLFTGNLDHVEFITIDIKEQKLYWAVTSTGVIEKGNVDGTNR-VTLVIHLS 1963
Query: 6064 QPNGLAFYGDRLFYADSAFDSIEVATINGDSQPPQWTHFKKDV--ENLANIKALQ----P 6225
P G+A Y L+Y D ++ IE + ++T K V +N+ +K L+
Sbjct: 1964 HPWGIAVYDTFLYYTDRDYEVIE--------RVDKFTGANKVVLRDNVPRLKCLRVYYRD 2015
Query: 6226 RASSSGHPCHINNGNCDHICIPLMFAQRTCTCANGY-VKDGQTSCKLFDESFVIVATKTK 6402
++ S + C N G C H+C+P+ +C CA G+ + +C ++ SFVIV+ +
Sbjct: 2016 NSAGSSNGCSNNIGVCQHLCLPVPGGLFSCACATGFQLNPDNRTCSPYN-SFVIVSMLSA 2074
Query: 6403 VIGYPIDETQSKGVAMEPIGGL--SITGVDYDYESKTIYVAEASGI---NKGITAYTIGE 6567
+ G+ + ET AM P+ G ++ VD S IY + S I
Sbjct: 2075 IKGFSL-ETSDHSEAMVPLAGRGRNVLHVDVHMPSGFIYWCDYSSTVSSQNAIRKIKPDG 2133
Query: 6568 SSPRAVIRDSIGSLTIKSLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTET 6747
S R V+ + IG I+ +AIDW+ N+YF N T IEV +L+ TYR++LL T +
Sbjct: 2134 SYFRNVVTNGIGRNGIRGIAIDWVAGNLYFTNAFLTETFIEVLRLNTTYRRVLLKTTIDM 2193
Query: 6748 PSSIAVDPVSRYLYWADQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWS 6927
P I VDP +RYL+WAD GQ P I+RSFLD + R V+VS GI P L +D ++ +YW
Sbjct: 2194 PRHIVVDPKNRYLFWADYGQNPKIERSFLDCTNRTVLVSEGIVTPRGLAIDHSNGYVYWV 2253
Query: 6928 DAKMDGIYRVRSTGGTPELVR--SDIASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTS 7101
D +D I R++ GG E+VR S + G+ + G +M W D L+K+F+A+ +P T
Sbjct: 2254 DDSLDMIARIQPDGGDVEIVRYGSRYPTPYGITIFGNSMIWVDRNLKKVFQASKEPGNTD 2313
Query: 7102 LLLSPTTVAASLKDIGDVAVFSSNNQPRASSPCQITDNL---RKSPCTQLCFATPGTQTP 7272
PT + ++ + DV +++S+ Q R SP + +N C LCFA P QTP
Sbjct: 2314 ---QPTVIRDNINWLRDVTIYNSHFQSR--SPLDVNNNPCLNNNGGCFHLCFALPDVQTP 2368
Query: 7273 TCSCARGVLK--GRTCE-EPDTYIMFSDGDKIIDVAIEPDVKASRPLKDPFPEISNLQT- 7440
C CA G L G+ C D Y++F+ + + + ++P+ + PF ++ L+T
Sbjct: 2369 QCGCAFGTLDSDGKRCTISTDDYLIFALENALRSIHLDPENHSP-----PFRAVNVLRTA 2423
Query: 7441 --FDVDVNLRRVYFVVESPVGVN-ISWFSMNNAENPRLVFGASKQPHAKEIRHISDMKLD 7611
D D R+YF P IS+ S+ + +V A ++ + D
Sbjct: 2424 VALDFDSINNRIYFTQSYPSRAGRISYISIYSGIGTPIVV-------ASDLGTPDGIAFD 2476
Query: 7612 WLTQKIYFTTGRGGKVMAIDTAGEHLSTIASGDWTYALAIDPCSGLLFWSDSGYKTSGGL 7791
W+ ++Y++ + ++ G + + IA A+ +DPC G ++W+D
Sbjct: 2477 WINNRVYYSDYLNQTISSMAVDGSNRTVIARVPRPRAVVLDPCRGYMYWTDWSSNA---- 2532
Query: 7792 YEPRIERSNLAGGSRKVIVSESISLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKV 7971
+IER+ L G R IVS ++ P + +D+ Q++YWAD N IE G NR+V
Sbjct: 2533 ---KIERATLGGNFRTPIVSTNLVWPNGLTLDYEEQQLYWADANLQKIERCTLTGTNREV 2589
Query: 7972 IAS-GYRAKSLDIWDRWLYMSDPLSNGVFRIDKESGSG-LENVVSDRRIPGALRVFASES 8145
I S ++ ++D+ +Y +D + ++R +K GS + +++ + P + V+A
Sbjct: 2590 IVSTALHPFAMTLFDQHIYWTDWNTRSIYRANKYDGSDQIVMIMNLPQRPMDIHVWA--- 2646
Query: 8146 DVRTRNQVCNALTSQLCKTDNGGCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDY 8325
+++ Q C + C NGGC +C G A ++ QC + L
Sbjct: 2647 --KSKQQQC----TNPCNQFNGGCSHICAP-----GPAGAECQCPSEGRWYLANNN---- 2691
Query: 8326 PTQCVLRGSNSEPAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCP 8505
C++ + C + F C +G CI CD+ DC D SDE + C +C
Sbjct: 2692 -KHCIV-----DNGTRCDTGF-FTCLNGHCISERWKCDNDNDCGDGSDELESVCAFHTCQ 2744
Query: 8506 EDYNLCTNRRCIDSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDG 8685
C N RC+ +C+H +DCGD SDE C + F C+NG CI+ VC+G
Sbjct: 2745 PTAFTCGNGRCVPYHYRCDHYNDCGDNSDEAGCLFRTCDSHTEFTCNNGRCISLQYVCNG 2804
Query: 8686 HNDCHDEQVSDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLF 8865
N+C+D SDE CP C+ +C +TNICI LCDG +DCGD +DE+
Sbjct: 2805 VNNCYDNGTSDER--NCPERT--CQSGFTKCQSTNICIPRTYLCDGDNDCGDMSDESPTH 2860
Query: 8866 CMNQQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCD 9045
C++ C + RC SGRCIP W CD DC+DG DE +C + C D F+CD
Sbjct: 2861 CVSMTCTNNEFRCTSGRCIPAHWYCDQGVDCADGSDEP-ASCEPHV--RTCSSDQ-FRCD 2916
Query: 9046 NLKCISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWL 9225
+ +CI +I RH C NR+CT EF C +N P CIPRAW+
Sbjct: 2917 DGRCIPATWICDGDNDCGDMSDEDQRHSCANRSCTATEFTCANNRP---PLRRCIPRAWV 2973
Query: 9226 CDGDVTCAGGEDESTELCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANC 9405
CDGD C+ DE + + C + EF C+N CI S + CD NDC D SDE C
Sbjct: 2974 CDGDADCSDALDEHQNCTR---RSCTENEFTCNNGLCIRSAYRCDRRNDCGDASDERG-C 3029
Query: 9406 TYSSCQPDFFQCANHKCVPNSWKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQCT 9585
Y CQ F C N +C+ ++ CDG++DC D SDE + + S +A+ CS F+C
Sbjct: 3030 IYEPCQQHQFTCQNGRCISKAYICDGDNDCGDESDELE---HLCSTPEAT-CSPQHFKCD 3085
Query: 9586 SGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFA 9765
+G CI+ AKVC+R +C D SDE C I+ECS C+ C D + + C C G+
Sbjct: 3086 NGNCIEMAKVCNRLDECLDNSDEKG-CGINECSDPSISGCDHVCTDTQTSFYCSCHPGYK 3144
Query: 9766 IDISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPF 9945
+ +SD+++C +++EC E S CSQ C++ GSY C C GY D SC++ P+
Sbjct: 3145 L-MSDKRTCDDIDECNETPSVCSQICENTAGSYICKCAPGYIREPDGKSCRQNS-NISPY 3202
Query: 9946 FLLANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMD 10125
+ +N++Y+R ++ DG Y L QG NVV+LD D EK+ Y ID G+ + R+ L+ +
Sbjct: 3203 LIFSNRYYLRNLTADGQSYSLILQGLRNVVALDFDRVEKRLYWIDVGRKVIERMFLNGTN 3262
Query: 10126 SPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDR---- 10293
E V+ +V EGIAVDWVGRKLY ++ + I V ELDGRF K L+ DR
Sbjct: 3263 K-----EAVISDDVPNGEGIAVDWVGRKLYWVDAYKDCIYVSELDGRFQKKLV-DRCVDI 3316
Query: 10294 -----IQQPKAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNA 10458
Q P+AIVVHP G +++T+W+ + YIGR +DG ++ + L WPN
Sbjct: 3317 NNTYCFQHPRAIVVHPKYGQVYWTDWADRAYIGRAGMDGKEKMV-----IISTKLEWPNG 3371
Query: 10459 IAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLRE 10638
+ IDY +D+L+W DAHLN I + D DG+ R + H ++ +F+D +YW DWN R
Sbjct: 3372 LTIDYTNDKLYWADAHLNYIEYSDLDGHHRHTVYDGTLPHPFAITIFEDTIYWTDWNTRT 3431
Query: 10639 VLRCDKWTGKNETILKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGY 10818
V + +K+ G T+L T P D+ + HP RQP NPCG NNGGCSHLCLI AGG GY
Sbjct: 3432 VEKGNKYDGSGRTVLVNTTHRPFDIHVYHPYRQPFVNNPCGTNNGGCSHLCLIKAGGQGY 3491
Query: 10819 TCSCPDQFVLLSDQKT--CEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGES 10992
+C CPD F+++ T C P C+ QF C D +CIP W CDG+ DCRDGSDEP
Sbjct: 3492 SCECPDNFMIVQFGSTAHCLPMCSSTQFLC-ADTERCIPIWWKCDGQRDCRDGSDEP--P 3548
Query: 10993 ICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXXEQ--------------------- 11109
C R CPVG+FQC + NCT P + E
Sbjct: 3549 TCPHRYCPVGQFQCNDGNCTSPHFLCNTQPDCHDRSDEDPVLCGEDSTVSFLEKLGDLMS 3608
Query: 11110 ----------------------NCDKACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDE 11223
+ + C+ ++C A RCIP + SDE
Sbjct: 3609 LWEMHPVALEICTSTGQPIYILSANHQCETHQWQC-ANKRCIPEAWQCDREDDCGDNSDE 3667
Query: 11224 ADTLCMSAERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXET-PEC--AQIECKKGWT 11394
T C A R C +F+C+N +CI ++W+ E EC C
Sbjct: 3668 DTTHC--ASRTCPPGQFKCDNGRCIPESWKCDVDDDCGDNSDEPFHECMGPAYRCDNHTQ 3725
Query: 11395 -RCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMCDTE 11571
C +SYRCIP WA CNG DDCRDNSDE TC G+FRC + +CIP RW CD +
Sbjct: 3726 FSCRTSYRCIPLWAVCNGNDDCRDNSDEQGCEEMTCSPFGDFRC-DNHRCIPLRWKCDGD 3784
Query: 11572 NDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTLRRC 11751
NDCGD SDE + S R C+ESE+RC++ +CIP VCD C D DE C LR C
Sbjct: 3785 NDCGDQSDEHNCS----PRECTESEYRCDNLRCIPSRWVCDHDDDCEDNSDERDCELRTC 3840
Query: 11752 LPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCED--VSRRTCSPFEFECANSVCIPRK 11925
PG+ QC+ G C+AE CD DC + +DE+ C + C P FEC N VCI
Sbjct: 3841 HPGYFQCNSGHCVAERFRCDGNADCLDFSDEITCPTRYPNGTYCPPMMFECKNHVCIQPY 3900
Query: 11926 FMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDE 12105
+ SDE C C+ P RFRC ++R C+ +LCN +DCG D SDE
Sbjct: 3901 WKCDGDNDCGDDSDEELHLCLDIACESPFRFRCENNR-CIYSHELCNQEDDCG--DGSDE 3957
Query: 12106 HLSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAF 12285
C + C++++FKC+NG C+ CD DDCGD DE+GC+ +T E
Sbjct: 3958 KEEHCREPTP-RPCTTEEFKCSNGNCIPLHYVCDNYDDCGDHFDEMGCNPGTERTCAENI 4016
Query: 12286 GNNGGCKHICTDVRD-GFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGSYL 12462
C+H CT++ + GF C CR G++ + C DI+EC TCTQ C N+KGSY
Sbjct: 4017 -----CEHNCTNLNEGGFICSCRPGYKASENNRNSCDDINECEIFGTCTQDCKNSKGSYE 4071
Query: 12463 CRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGSGTNRHXXXXXXXXX 12642
C C + +++ VG GK C A G+ +++ + + + ++ + +
Sbjct: 4072 CFCADGFKS---VGDQQGKQCAANGNPPLLLLPDNVRIRRYNISSEQYSDYIDNQERIQA 4128
Query: 12643 XXXXXXXXXPRKELMYW---IDGSE-RTIYRSAIANGNQSHEGQKLDVDFAAMGVV-PTA 12807
++Y+ GS+ I R+ + + S +VD +V P
Sbjct: 4129 LDYDWDPEGIGLSIVYFSILAQGSQFGAIKRAYLPTFDSSRNNPTKEVDLNLRYIVNPDG 4188
Query: 12808 IAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGH 12987
+AVD+ +L+ + T I V DGRY K ++
Sbjct: 4189 LAVDWVGRHLYWT-----------------------DAGTNRIEVAKLDGRYRKWLIFSL 4225
Query: 12988 LQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNR 13167
L QP A+ P G + ++D G KIECA MDG R+ +V + + PT ++ID +R
Sbjct: 4226 LDQPAAIAVNPKHGLMYWTDWGRQPKIECAWMDGQQRRTLVSEDLGWPTGLSIDYLNNDR 4285
Query: 13168 IYWVDPKYRRVDAVNIDGSERTTVVH-DRHIPYAVDVFENHIYWLSRESKTLYVQDKFGR 13344
IYW D K ++++ DG++RT V+H + PY++DVFE H+YW+++E ++ +DKFG
Sbjct: 4286 IYWSDSKENIIESMRHDGTDRTVVLHGEVGSPYSLDVFEGHLYWIAKERGEVWKKDKFGN 4345
Query: 13345 GRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTGFACLCPDG--I 13518
G + + VR+ ++ + Q + C+ CSHLC+ P G+ C CP G
Sbjct: 4346 GEKVKVLTVNPWLTQVRIYHQH-RYNQSVPNPCKDV-CSHLCLLRPG-GYTCACPQGTRF 4402
Query: 13519 VPQLDGSCATQHVEALTMPKQCKCTNGGKCRLDGS----CECTSDFEGDQCE 13662
V C TMP C+C GG C +D S C+C+ + GD CE
Sbjct: 4403 VEGSSTECDAAIESPPTMPPACRCMYGGTCYIDESGLPKCKCSYGYTGDYCE 4454
Score = 433 bits (1114), Expect = e-119
Identities = 310/1055 (29%), Positives = 464/1055 (43%), Gaps = 66/1055 (6%)
Frame = +1
Query: 148 SSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPG---------------CKS 282
++ C+ + F C +G+CI + W P G C
Sbjct: 1066 NNTCSSSAFTCANGQCIPSRWRCDKHNDCFDGSDELRCPTQGPTSCPETLFTCDNNRCIP 1125
Query: 283 DQWQCDT-----------------------YTWHSVSCIAEYQRCDNITDCADGSDEKDC 393
W CDT + CI Y CD DC DG+DE DC
Sbjct: 1126 RIWLCDTDNDCGDGSDEKNCTFTGTCEPRQFQCPDHRCIDPYYVCDGDKDCVDGADEHDC 1185
Query: 394 PASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCAD 573
+CS F C G QC +CDG +DC D SDE D +R C Q +F+C
Sbjct: 1186 ---IYNCSGTE-FKCVSGDQCISSYYQCDGVFDCNDHSDETDCPTRPPGMCHQNEFQCQS 1241
Query: 574 KTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDN 753
CI +W CDG DCADGSDE C + C + F+C N C R + CD +DC D
Sbjct: 1242 DGNCIPANWECDGHLDCADGSDEHHRCPARTCPPSLFRCDNGNCVYRAWICDGDNDCRDM 1301
Query: 754 SDEDEC--GEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQ-CSQNLCP--SLG 918
SDE +C +RCP +W CPG C++ K+CD S DC +GADE C+Q C + G
Sbjct: 1302 SDERDCPTQPFRCPSWQWQCPGHSICVNLSKVCDNSADCPNGADESPLCNQESCSDNNAG 1361
Query: 919 CQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGD 1098
C C P G +CTCP GY+L + +TC DINEC G+C Q C N R F C C +
Sbjct: 1362 CTHECIQGPFGAQCTCPVGYQLTND-SKTCEDINECDPPGFCSQHCYNERGSFRCYC-DE 1419
Query: 1099 CFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKL-ASGEF 1275
+ L+ T C + + L VA R + N + + L G
Sbjct: 1420 GYILE----------TNGRTCKVAESGNLLLLVASRNQIVVDNITSQSHSIYSLIRDGRN 1469
Query: 1276 IYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTL 1455
I IDFD +IFW+D +SA + + K + + +AVDW+ L
Sbjct: 1470 IVAIDFDSISDRIFWSDTTQDKIWSAYQNG----TDRKVVFDSGVTVTESIAVDWVGRNL 1525
Query: 1456 YIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPL--RGEMFFTN---QLKLEAAA 1620
Y + I+VS DG RTVL+++ +T P + LDP MF+T+ ++E A+
Sbjct: 1526 YWTDFVLETIEVSKMDGSHRTVLISENVTNPRGLVLDPRIDAHVMFWTDWGQNPRIEKAS 1585
Query: 1621 MDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVP 1800
MDG R ++++ + +G+ +D K +Y+ D +D ++ DY GN+RR V V+
Sbjct: 1586 MDGKLRTVIISSKIYWPNGLSIDYPNKLLYFADAYLDYIDFCDYNGNNRRQVVASDLVLQ 1645
Query: 1801 HPFGLALFDQYLYWTDWTRLGVIQVEKF--GSDTKLLWSNTENNVFPMGISAYHPMAQPG 1974
HP GL +F+ ++YW+D VI+ K+ G+ T ++++ + P+G+ A HP+ QP
Sbjct: 1646 HPHGLTIFEDFVYWSDRYTNRVIRANKWHGGNQTVMIYNIHQ----PLGLVAVHPVKQPY 1701
Query: 1975 PGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGKRCIDSID-- 2148
N C ++ C +C+LS F + CACP G L R ++
Sbjct: 1702 G----------INSCASSPCSHLCLLSSSGPLF---FSCACPSGWMLSPDNRNCMRVEHP 1748
Query: 2149 YLLFSSNKIVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDN 2328
+L+ + I+ GI EK +A++PI+ + +V+ D ++ +
Sbjct: 1749 FLIAVRDNIIYGISLNPEEKT-NDAMVPIAGVQNG-----VDVDFDDSEQMIYWVE-NPG 1801
Query: 2329 TIYRIRPDGEGA---APVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVH 2499
I+R+R DG AP V ++ DWIS LYY + S+EV+K+ H
Sbjct: 1802 EIHRVRSDGSNRTVFAPAAVI--GAPIGLALDWISANLYYSNPGTQSIEVLKL------H 1853
Query: 2500 PDELVRRQLITE------LRDPVSVVVHPWKGLLFY----AEAMRPAAIYRCHIDGQNCQ 2649
+ + R+ LIT P+ + V P +G L++ ++ PA + ++DG Q
Sbjct: 1854 GEVMYRKTLITNDGTSLGAGTPIGLTVDPARGKLYWTDQGTDSGVPAKVASANMDGSGIQ 1913
Query: 2650 VIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVKLDIDNPIPVAITIMNE 2829
+ L + ID E +L W T I + DG N V L I P I + +
Sbjct: 1914 TLFTGNLDHVEFITIDIKEQKLYWAVTSTGVIEKGNVDGTNRVTLVIHLSHPWGIAVYDT 1973
Query: 2830 YIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRA 3009
++YY + I RV K G ++R+ + + L+ N S
Sbjct: 1974 FLYYTDRDYEVIERVDKFTGANKVVLRD---NVPRLKCLRVYYRDNS--AGSSNGCSNNI 2028
Query: 3010 SQCTQLCFATPSESHPNELEAKCACRQGFMINKEN 3114
C LC P CAC GF +N +N
Sbjct: 2029 GVCQHLCLPVPGGLF------SCACATGFQLNPDN 2057
Score = 302 bits (773), Expect = 2e-79
Identities = 215/778 (27%), Positives = 324/778 (41%), Gaps = 26/778 (3%)
Frame = +1
Query: 8614 VACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPGLPIDCRGVKVRCPNTNI 8793
+ C G F C NG CI CDG DC D+ +DE A CP C G + +C
Sbjct: 31 IGCGGGQFRCGNGRCIPADWRCDGARDCSDD--TDE--AGCP--QPTCEGNQFQCQTDGE 84
Query: 8794 CIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWD 8973
CI + +CD +DC D +DE+Q C + C+ C +G+CIP ++CD DC+DG D
Sbjct: 85 CIPHSWVCDDEEDCEDGSDEHQQ-CPGRTCSSQQFTCSNGQCIPSAYRCDRVKDCTDGTD 143
Query: 8974 ETHTNCTDTAGKKICVGDYLFQCDNLKCISRA-FIXXXXXXXXXXXXXHSRHGCGNRTCT 9150
E +C+ L C + A F S R C
Sbjct: 144 ERDCRYP--------------RCEQLSCANGACFNASQRCDGKVDCRDTSDEANCTRGCA 189
Query: 9151 DQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECNKGEFRCSNQ 9330
+F C + ECIP+A++CD D C DE++ T C F C +
Sbjct: 190 STQFQCANG--------ECIPQAFMCDHDDDCGDRSDENSCTYAT----CRGNFFTCPSG 237
Query: 9331 HCIHSTWECDGDNDCLDGSDEH-ANCTYSSCQPDFFQC-ANHKCVPNSWKCDGNDDCEDG 9504
CIH +W CDGD+DC D DE +Y C P + C + C+P CDG DC G
Sbjct: 238 RCIHQSWICDGDDDCEDNEDERGCESSYHECYPGEWACPESGHCIPIGKVCDGAADCPAG 297
Query: 9505 SDEKD-----------CPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSD 9651
DE + C S + S S G C SG I S+
Sbjct: 298 EDETNITAGRHCNISHCAALSCQYRCHSSPSGGMCYCPSGYTIS--------------SN 343
Query: 9652 ESSLCF-IDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNECYEGISG 9828
+S C D+C + +C+Q C D ++C C EG+ ++
Sbjct: 344 DSRTCIDFDDCKM--WGVCDQLCEDRVGHHQCHCVEGYFLE------------------- 382
Query: 9829 CSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYEL 10008
C+ + +N + + G +
Sbjct: 383 ------------------------HHRHCRANTSAGVASIIFSNGRDLLIGDLHGRNFRT 418
Query: 10009 AAQGFDNVVSLDID--LTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEG 10182
Q + V++ +D + + D + ++ +++D D ++ VL +V E
Sbjct: 419 LVQSQNRGVAVGVDFHFYLHRIFWTDTVQDKVFSINIDGSD-----FQEVLNVSVDTPEN 473
Query: 10183 IAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFFTEW-- 10356
+AVDWV KLY++ I + LDG TLI + + P+ I + P GYLFF++W
Sbjct: 474 LAVDWVNNKLYVVETSVNRIDMVNLDGTNRVTLIAENLGNPRGIALDPTVGYLFFSDWDS 533
Query: 10357 -SLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDF 10533
S P + R +DG+ QD L + LGWP I +D S RL+W D+ + I + +
Sbjct: 534 LSGDPKVERAFMDGT-NRQD----LIKTKLGWPAGITLDIVSKRLYWVDSRFDYIETVTY 588
Query: 10534 DGNGRRHIP--AQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPN 10707
DG RR I H + +F+ +Y+ DW V++ +K++ N ++ ++ P
Sbjct: 589 DGLQRRTIAHGGSLIPHPYGITLFEHNVYFTDWTKMAVVKANKFSESNPQVIYQSSLRPY 648
Query: 10708 DLRIVHPMRQPAYPNPCGDNNGGCSHLCLIG----AGGNGYTCSCPDQFVLLSDQKTC 10869
+ + H RQP NPCG+NNGGC +C++ G GY C C F L D + C
Sbjct: 649 GVTVYHAARQPYVRNPCGNNNGGCEQICVLSHKTDNDGLGYRCRCILGFDLHVDGRHC 706
Score = 291 bits (745), Expect = 3e-76
Identities = 215/740 (29%), Positives = 315/740 (42%), Gaps = 18/740 (2%)
Frame = +1
Query: 11371 IECKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPR 11550
I C G RC + RCIP C+G DC D++DE PTC+ +F+C T G+CIP
Sbjct: 31 IGCGGGQFRCGNG-RCIPADWRCDGARDCSDDTDEAGCPQPTCEG-NQFQCQTDGECIPH 88
Query: 11551 RWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDES 11730
W+CD E DC D SDE C G T CS +F C++G+CIP + CD C+DG DE
Sbjct: 89 SWVCDDEEDCEDGSDE-HQQCPGRT--CSSQQFTCSNGQCIPSAYRCDRVKDCTDGTDER 145
Query: 11731 QCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFECANSV 11910
C RC C +G C + CD K DC + +DE +C R C+ +F+CAN
Sbjct: 146 DCRYPRC--EQLSCANGACFNASQRCDGKVDCRDTSDEANCT----RGCASTQFQCANGE 199
Query: 11911 CIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPN 12090
CIP+ FM SDE S C A C F C R C++ +C+G +DC N
Sbjct: 200 CIPQAFMCDHDDDCGDRSDENS--CTYATCRGNF-FTCPSGR-CIHQSWICDGDDDCEDN 255
Query: 12091 DFSDEHLSMCSSFSEYGDCSSDQFKCA-NGKCVNGTVACDRKDDCGDASDE--IGCSKHG 12261
+ DE S Y +C ++ C +G C+ CD DC DE I +H
Sbjct: 256 E--DER----GCESSYHECYPGEWACPESGHCIPIGKVCDGAADCPAGEDETNITAGRHC 309
Query: 12262 GKTSCEAFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCL 12441
+ C A C++ C G C+C G+ + CID D+C C QLC
Sbjct: 310 NISHCAALS----CQYRCHSSPSGGMCYCPSGYTISSNDSRTCIDFDDCKMWGVCDQLCE 365
Query: 12442 NTKGSYLCRCHEDY--ENNVVVGSMTGKDCRAKGDA--ANVMIGADDSLVQLSLHGSGTN 12609
+ G + C C E Y E++ + CRA A A+++ L+ LHG
Sbjct: 366 DRVGHHQCHCVEGYFLEHH--------RHCRANTSAGVASIIFSNGRDLLIGDLHGRNFR 417
Query: 12610 RHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAM 12789
R ++W D + ++ S +G+ E + VD
Sbjct: 418 TLVQSQNRGVAVGVDFHFYLHR---IFWTDTVQDKVF-SINIDGSDFQEVLNVSVD---- 469
Query: 12790 GVVPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLK 12969
P +AVD+ L++ S N ID N DG
Sbjct: 470 --TPENLAVDWVNNKLYVVETSVN---------------RIDMVNL--------DGTNRV 504
Query: 12970 KIVAGHLQQPTALITAPSAGRICYSD---AGLHAKIECADMDGTHRQIIVKDLVFSPTSM 13140
++A +L P + P+ G + +SD K+E A MDGT+RQ ++K + P +
Sbjct: 505 TLIAENLGNPRGIALDPTVGYLFFSDWDSLSGDPKVERAFMDGTNRQDLIKTKLGWPAGI 564
Query: 13141 AIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHI---PYAVDVFENHIYWLSRES 13311
+D R+YWVD ++ ++ V DG +R T+ H + PY + +FE+++Y+
Sbjct: 565 TLDI-VSKRLYWVDSRFDYIETVTYDGLQRRTIAHGGSLIPHPYGITLFEHNVYFTDWTK 623
Query: 13312 KTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPST- 13488
+ +KF V+ + V V + R G C +CV T
Sbjct: 624 MAVVKANKFSESNPQVIYQSSLRPYGVTVYHAARQPYVRNPCGNNNGGCEQICVLSHKTD 683
Query: 13489 ----GFACLCPDGIVPQLDG 13536
G+ C C G +DG
Sbjct: 684 NDGLGYRCRCILGFDLHVDG 703
Score = 289 bits (740), Expect = 1e-75
Identities = 200/683 (29%), Positives = 299/683 (43%), Gaps = 32/683 (4%)
Frame = +1
Query: 148 SSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHP---GCKSDQWQCDTYTWHS 318
S C N+FRC G+CI W P C SDQ++CD
Sbjct: 2863 SMTCTNNEFRCTSGRCIPAHWYCDQGVDCADGSDEPASCEPHVRTCSSDQFRCD-----D 2917
Query: 319 VSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADG----RQCFDVSKKCDGK 486
CI CD DC D SDE + + F CA+ R+C + CDG
Sbjct: 2918 GRCIPATWICDGDNDCGDMSDEDQRHSCANRSCTATEFTCANNRPPLRRCIPRAWVCDGD 2977
Query: 487 YDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKK 666
DC D DE +C+R +C + +F C + CI+ ++ CD DC D SDE C ++
Sbjct: 2978 ADCSDALDEHQNCTRR--SCTENEFTC-NNGLCIRSAYRCDRRNDCGDASDERG-CIYEP 3033
Query: 667 CTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDE--CG--EYRCPPGKWNCPGTGHCIDQ 834
C ++F C+N RC + + CD +DCGD SDE E C E C P + C G+CI+
Sbjct: 3034 CQQHQFTCQNGRCISKAYICDGDNDCGDESDELEHLCSTPEATCSPQHFKC-DNGNCIEM 3092
Query: 835 LKLCDGSKDCADGADEQQCSQNLC--PSL-GCQAGCHPSPHGGECTCPSGYKL-DDRFHR 1002
K+C+ +C D +DE+ C N C PS+ GC C + C+C GYKL D+ R
Sbjct: 3093 AKVCNRLDECLDNSDEKGCGINECSDPSISGCDHVCTDTQTSFYCSCHPGYKLMSDK--R 3150
Query: 1003 TCSDINECAEF-GYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNAD 1179
TC DI+EC E C Q+C N + C C PG C N+
Sbjct: 3151 TCDDIDECNETPSVCSQICENTAGSYICKC-----------APGYIREPDGKSCRQNSNI 3199
Query: 1180 KMKLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTD---RLAHSAFS 1350
L + R L L + L + +DFD +++++W D ++ F
Sbjct: 3200 SPYLIFSNRYYLRNLTADGQSYSL-ILQGLRNVVALDFDRVEKRLYWIDVGRKVIERMFL 3258
Query: 1351 ADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLA 1530
+ E IS + +AVDW+ LY +++ I VS DG + L+
Sbjct: 3259 NGTNKEAVISD-------DVPNGEGIAVDWVGRKLYWVDAYKDCIYVSELDGRFQKKLVD 3311
Query: 1531 DGLTL--------PLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVSG 1677
+ + P I + P G++++T ++ + A MDG + +++T +G
Sbjct: 3312 RCVDINNTYCFQHPRAIVVHPKYGQVYWTDWADRAYIGRAGMDGKEKMVIISTKLEWPNG 3371
Query: 1678 IVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTR 1857
+ +D T ++YW D ++ +E D G+ R V G +PHPF + +F+ +YWTDW
Sbjct: 3372 LTIDYTNDKLYWADAHLNYIEYSDLDGHHRHTVYDG--TLPHPFAITIFEDTIYWTDWNT 3429
Query: 1858 LGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPC--TNAD 2031
V + K+ + + NT + P I YHP QP + NPC N
Sbjct: 3430 RTVEKGNKYDGSGRTVLVNTTHR--PFDIHVYHPYRQP----------FVNNPCGTNNGG 3477
Query: 2032 CEGMCILSKDNGGFGVGYKCACP 2100
C +C++ G GY C CP
Sbjct: 3478 CSHLCLIKAG----GQGYSCECP 3496
Score = 255 bits (652), Expect = 2e-65
Identities = 220/777 (28%), Positives = 322/777 (41%), Gaps = 113/777 (14%)
Frame = +1
Query: 133 SVNTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTW 312
+ + AS C F+C++G+CI W P C ++CD +T
Sbjct: 3669 TTHCASRTCPPGQFKCDNGRCIPESW---KCDVDDDCGDNSDEPFHECMGPAYRCDNHTQ 3725
Query: 313 H----SVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCD 480
S CI + C+ DC D SDE+ C T CS F C D +C + KCD
Sbjct: 3726 FSCRTSYRCIPLWAVCNGNDDCRDNSDEQGCEEMT--CSPFGDFRC-DNHRCIPLRWKCD 3782
Query: 481 GKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEF 660
G DC D SDE + R C + ++RC D +CI WVCD DC D SDE D CE
Sbjct: 3783 GDNDCGDQSDEHNCSPRE---CTESEYRC-DNLRCIPSRWVCDHDDDCEDNSDERD-CEL 3837
Query: 661 KKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDEC------GEYRCPPGKWNCPGTGH 822
+ C FQC + C +FRCD DC D SDE C G Y CPP + C
Sbjct: 3838 RTCHPGYFQCNSGHCVAERFRCDGNADCLDFSDEITCPTRYPNGTY-CPPMMFECK-NHV 3895
Query: 823 CIDQLKLCDGSKDCADGADEQQCSQNLCPSLGCQAG----------------CHPSPHGG 954
CI CDG DC D +DE+ +LC + C++ C+ G
Sbjct: 3896 CIQPYWKCDGDNDCGDDSDEE---LHLCLDIACESPFRFRCENNRCIYSHELCNQEDDCG 3952
Query: 955 E----------------CT-----CPSGYKLDDRFHRTCSDINECAEF------------ 1035
+ CT C +G + H C + ++C +
Sbjct: 3953 DGSDEKEEHCREPTPRPCTTEEFKCSNGNCIP--LHYVCDNYDDCGDHFDEMGCNPGTER 4010
Query: 1036 ----GYCDQLCAN-HRPGFTCSC----------------------LGDCFTLQMEHGPG- 1131
C+ C N + GF CSC G C T ++ G
Sbjct: 4011 TCAENICEHNCTNLNEGGFICSCRPGYKASENNRNSCDDINECEIFGTC-TQDCKNSKGS 4069
Query: 1132 ---------KDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKLASGEFIYG 1284
K +G + N + L + + R N + ++ + + E I
Sbjct: 4070 YECFCADGFKSVGDQQGKQCAANGNPPLLLLPDNVRIRRYNISS-EQYSDYIDNQERIQA 4128
Query: 1285 IDFDY-----GDRKIFWTDRLAHSAFSA------DVDDEGEISQIKKLSL--KSLVYPRC 1425
+D+D+ G ++++ S F A D + K++ L + +V P
Sbjct: 4129 LDYDWDPEGIGLSIVYFSILAQGSQFGAIKRAYLPTFDSSRNNPTKEVDLNLRYIVNPDG 4188
Query: 1426 LAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTN--- 1596
LAVDW+ LY ++G+ RI+V+ DG R L+ L P IA++P G M++T+
Sbjct: 4189 LAVDWVGRHLYWTDAGTNRIEVAKLDGRYRKWLIFSLLDQPAAIAVNPKHGLMYWTDWGR 4248
Query: 1597 QLKLEAAAMDGTNRRTLVNTHTHQVSGIVVD-ITAKRVYWVDPKVDRLESIDYQGNDRRI 1773
Q K+E A MDG RRTLV+ +G+ +D + R+YW D K + +ES+ + G DR +
Sbjct: 4249 QPKIECAWMDGQQRRTLVSEDLGWPTGLSIDYLNNDRIYWSDSKENIIESMRHDGTDRTV 4308
Query: 1774 VAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAY 1953
V G V P+ L +F+ +LYW R V + +KFG+ K+ N + + Y
Sbjct: 4309 VLHG--EVGSPYSLDVFEGHLYWIAKERGEVWKKDKFGNGEKVKVLTV--NPWLTQVRIY 4364
Query: 1954 HPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNG 2124
H Q QS + NPC + C +C+L GY CACP G + V G
Sbjct: 4365 H---QHRYNQS------VPNPCKDV-CSHLCLLRPG------GYTCACPQGTRFVEG 4405
Score = 151 bits (381), Expect = 5e-34
Identities = 105/363 (28%), Positives = 156/363 (42%), Gaps = 19/363 (5%)
Frame = +1
Query: 145 ASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVS 324
A C F C +G+C+ + C S +T ++
Sbjct: 2739 AFHTCQPTAFTCGNGRCVPYHYRCDHYNDCGDNSDEAGCLFRTCDSH----TEFTCNNGR 2794
Query: 325 CIAEYQRCDNITDCADG--SDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCR 498
CI+ C+ + +C D SDE++CP T C S C C + CDG DC
Sbjct: 2795 CISLQYVCNGVNNCYDNGTSDERNCPERT--CQS-GFTKCQSTNICIPRTYLCDGDNDCG 2851
Query: 499 DLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCE--FKKCT 672
D+SDE + + T C +FRC +CI W CD DCADGSDEP +CE + C+
Sbjct: 2852 DMSDESPTHCVSMT-CTNNEFRCT-SGRCIPAHWYCDQGVDCADGSDEPASCEPHVRTCS 2909
Query: 673 ANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDE---CGEYRCPPGKWNC----PGTGHCID 831
+++F+C + RC P + CD +DCGD SDED+ C C ++ C P CI
Sbjct: 2910 SDQFRCDDGRCIPATWICDGDNDCGDMSDEDQRHSCANRSCTATEFTCANNRPPLRRCIP 2969
Query: 832 QLKLCDGSKDCADGADE-QQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTC 1008
+ +CDG DC+D DE Q C++ C E TC +G + + C
Sbjct: 2970 RAWVCDGDADCSDALDEHQNCTRRSCTE-------------NEFTCNNGLCIRSAYR--C 3014
Query: 1009 SDINECA----EFGYCDQLCANHRPGFTCS---CLGDCFTLQMEHGPGKDNLTMRGYCVS 1167
N+C E G + C H+ FTC C+ + ++ G ++ + C +
Sbjct: 3015 DRRNDCGDASDERGCIYEPCQQHQ--FTCQNGRCISKAYICDGDNDCGDESDELEHLCST 3072
Query: 1168 NNA 1176
A
Sbjct: 3073 PEA 3075
Score = 100 bits (248), Expect = 1e-18
Identities = 79/267 (29%), Positives = 109/267 (40%), Gaps = 16/267 (5%)
Frame = +1
Query: 3676 VQCSALQFRCANGRQCVPLRNHXXXXXXXXXXXXXXXXAVTAESCTPDQFKCVSSGLCIP 3855
+ C QFRC NGR C+P +C +QF+C + G CIP
Sbjct: 31 IGCGGGQFRCGNGR-CIPA--DWRCDGARDCSDDTDEAGCPQPTCEGNQFQCQTDGECIP 87
Query: 3856 ASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKCGNGRCILNNWLCDGENDCGDGSDES 4035
SW SDE + GR CSS QF C NG+CI + + CD DC DG+D
Sbjct: 88 HSWVCDDEEDCEDGSDEHQ--QCPGRTCSSQQFTCSNGQCIPSAYRCDRVKDCTDGTD-- 143
Query: 4036 SERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGGRCARDLCSADR 4215
ER C+ +C E ++C N C Q CDGK C +DE C+
Sbjct: 144 -ERDCRYP----RC--EQLSCANG--ACFNASQRCDGKVDCRDTSDEAN------CTRGC 188
Query: 4216 AGCSFKCHNSPNGPICSCPFGEQLVNKTKCEPENEC---LDSSSC-------------SQ 4347
A F+C N GE + C+ +++C D +SC S
Sbjct: 189 ASTQFQCAN-----------GECIPQAFMCDHDDDCGDRSDENSCTYATCRGNFFTCPSG 237
Query: 4348 RCKDEKHGFTCSCDEGYELDVDKRTCK 4428
RC + + C D+ E + D+R C+
Sbjct: 238 RCIHQ--SWICDGDDDCEDNEDERGCE 262
Score = 70.9 bits (172), Expect = 9e-10
Identities = 110/460 (23%), Positives = 171/460 (36%), Gaps = 28/460 (6%)
Frame = +1
Query: 5266 CSHLCLLNNKNTFTCKCPMGEKL--DASGKKCIDDAKPFLVIIQKTNVFGIEMNSASEKE 5439
C+ C N+K ++ C C G K D GK+C + P L+++ NV N +SE+
Sbjct: 4059 CTQDCK-NSKGSYECFCADGFKSVGDQQGKQCAANGNPPLLLLPD-NVRIRRYNISSEQY 4116
Query: 5440 TPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTV-----N 5604
+ + + L +D LS F + LAQ + AI R+ + +
Sbjct: 4117 SDYIDNQERIQALDYDWDPEGIGLSIVYFSI--------LAQGSQFGAIKRAYLPTFDSS 4168
Query: 5605 GGNKTKMFSSAV-----PDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVILSN 5769
N TK + PD L DW GR+L + T IE+ + G+ + +I S
Sbjct: 4169 RNNPTKEVDLNLRYIVNPDG---LAVDWVGRHLYWTDAGTNRIEVAKLDGRYRKWLIFSL 4225
Query: 5770 -DQSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDH 5946
DQ G ++W D G K+ A +DG + S DL
Sbjct: 4226 LDQPAAIAVNPKH-------GLMYWTDWG---RQPKIECAWMDGQQRRTLVSEDLGWPTG 4275
Query: 5947 IAID-TTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSA-- 6117
++ID N R+Y+S++K I S+ +DG DR VL P L + L++
Sbjct: 4276 LSIDYLNNDRIYWSDSKENIIESMRHDGTDRTVVLHGEVGSPYSLDVFEGHLYWIAKERG 4335
Query: 6118 ----------FDSIEVATINGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHINNG 6267
+ ++V T+N P T + ++ N S +PC
Sbjct: 4336 EVWKKDKFGNGEKVKVLTVN-----PWLTQVRIYHQHRYN--------QSVPNPC---KD 4379
Query: 6268 NCDHICIPLMFAQRTCTCANG--YVKDGQTSCKLFDESFVIVATKTKVIGYPIDETQSKG 6441
C H+C+ L TC C G +V+ T C ES + P G
Sbjct: 4380 VCSHLCL-LRPGGYTCACPQGTRFVEGSSTECDAAIESPPTMP--------PACRCMYGG 4430
Query: 6442 VAMEPIGGLSITGVDYDYESKTIYVAEASGINKGITAYTI 6561
GL Y Y + + G+ G TA +
Sbjct: 4431 TCYIDESGLPKCKCSYGYTGDYCEIGLSKGVPPGTTAVAV 4470
Score = 64.3 bits (155), Expect = 8e-08
Identities = 52/205 (25%), Positives = 77/205 (37%), Gaps = 42/205 (20%)
Frame = +1
Query: 3946 DQFKCGNGR-------CILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACEN 4104
D CG G+ CI +W CDG DC D +DE+ GC C C+
Sbjct: 29 DLIGCGGGQFRCGNGRCIPADWRCDGARDCSDDTDEA---GCPQP----TCEGNQFQCQT 81
Query: 4105 DQETCIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCS--------FKCH------- 4239
D E CIP +CD + C G+DE +C CS+ + CS ++C
Sbjct: 82 DGE-CIPHSWVCDDEEDCEDGSDEHQQCPGRTCSSQQFTCSNGQCIPSAYRCDRVKDCTD 140
Query: 4240 -------NSPNGPICSCPFGEQLVNKTKCEPENECLDSS---SCSQRCKDEK-------- 4365
P SC G +C+ + +C D+S +C++ C +
Sbjct: 141 GTDERDCRYPRCEQLSCANGACFNASQRCDGKVDCRDTSDEANCTRGCASTQFQCANGEC 200
Query: 4366 --HGFTCSCDEGYELDVDKRTCKVA 4434
F C D+ D+ +C A
Sbjct: 201 IPQAFMCDHDDDCGDRSDENSCTYA 225
Score = 52.0 bits (123), Expect = 4e-04
Identities = 34/144 (23%), Positives = 46/144 (31%), Gaps = 5/144 (3%)
Frame = +1
Query: 151 SVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCI 330
+ C N F C G+CI W
Sbjct: 225 ATCRGNFFTCPSGRCIHQSWI--------------------------------------- 245
Query: 331 AEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSD 510
CD DC D DE+ C +S +C + C + C + K CDG DC D
Sbjct: 246 -----CDGDDDCEDNEDERGCESSYHEC-YPGEWACPESGHCIPIGKVCDGAADCPAGED 299
Query: 511 EKD-----SCSRNHTACFQYQFRC 567
E + C+ +H A Q+RC
Sbjct: 300 ETNITAGRHCNISHCAALSCQYRC 323
Score = 51.6 bits (122), Expect = 6e-04
Identities = 45/149 (30%), Positives = 58/149 (38%), Gaps = 33/149 (22%)
Frame = +1
Query: 715 KFRCDYY--DDCGDNSDEDECGEYRCPPGKWNCPGT------------------------ 816
+ C +Y D G + CG RC P W C G
Sbjct: 20 RLTCLFYPRDLIGCGGGQFRCGNGRCIPADWRCDGARDCSDDTDEAGCPQPTCEGNQFQC 79
Query: 817 ---GHCIDQLKLCDGSKDCADGADE-QQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKL 984
G CI +CD +DC DG+DE QQC C S Q C G+C PS Y+
Sbjct: 80 QTDGECIPHSWVCDDEEDCEDGSDEHQQCPGRTCSSQ--QFTC----SNGQC-IPSAYRC 132
Query: 985 DDRFHRTCSDINECAEFGY--CDQL-CAN 1062
D + C+D + + Y C+QL CAN
Sbjct: 133 DR--VKDCTDGTDERDCRYPRCEQLSCAN 159
>gi|13562118|ref|NP_110454.1| low density lipoprotein receptor-related
protein 2; glycoprotein 330; low density
lipoprotein-related protein 2; megalin [Rattus norvegicus]
gi|1708867|sp|P98158|LRP2_RAT Low-density lipoprotein receptor-related
protein 2 precursor (Megalin) (Glycoprotein 330) (gp330)
gi|11275227|pir||T42737 gp330 protein precursor - rat
gi|561853|gb|AAA51369.1| megalin
Length = 4660
Score = 2602 bits (6743), Expect = 0.0
Identities = 1608/4881 (32%), Positives = 2408/4881 (48%), Gaps = 177/4881 (3%)
Frame = +1
Query: 145 ASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKS-------------D 285
+S C +FRC++G CI W P C+S
Sbjct: 24 SSQECGSGNFRCDNGYCIPASWRCDGTRDCLDDTDEIGCPPRSCESGLFLCPAEGTCIPS 83
Query: 286 QWQCD-----------------------TYTWHSVSCIAEYQRCDNITDCADGSDEKDCP 396
W CD T + CI RCD+++DC DGSDE++C
Sbjct: 84 SWVCDEDKDCSDGADEQQNCAGTTCSAQQMTCSNGQCIPSEYRCDHVSDCPDGSDERNCH 143
Query: 397 ASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADK 576
T D CA+G C++ S++CD K DCRD SDE +C+ T C Q +F C
Sbjct: 144 YPTCD-----QLTCANG-ACYNTSQRCDQKVDCRDSSDEA-NCT---TLCSQKEFECG-S 192
Query: 577 TQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNS 756
+CI +++VCD DC D SDE + C + C ++F C N +C + + CD DDC D+
Sbjct: 193 GECILRAYVCDHDNDCEDNSDERN-CNYDTCGGHQFTCSNGQCINQNWVCDGDDDCQDSG 251
Query: 757 DEDEC----GEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADE------QQCSQNLC 906
DED C +RC P +W CPG+G CI K+CDG DC +G DE + C +C
Sbjct: 252 DEDGCESNQSHHRCYPREWACPGSGRCISIDKVCDGVPDCPEGDDENNVTSGRTCGMGVC 311
Query: 907 PSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCS 1086
L C+ CH +P GGEC CP G+ ++ RTC D ++C +G CDQ C N + C
Sbjct: 312 SVLNCEYQCHQTPFGGECFCPPGHIINSNDSRTCIDFDDCQIWGICDQKCENRQGRHQCL 371
Query: 1087 CLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKLAS 1266
C + +H D+ + SN D + + R KN
Sbjct: 372 CEEGYILERGQHCKSSDSFSAASVIFSNGRDLLVGDLHGRNFRILAESKNRG-------- 423
Query: 1267 GEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWIT 1446
+ G+DF Y ++FWTD + FS D++ +I +S+ + P LAVDWI
Sbjct: 424 --MVMGVDFHYQKHRVFWTDPMQEKVFSTDINGL-NTQEILNVSVDT---PENLAVDWIN 477
Query: 1447 NTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTN------QLKL 1608
N LY++E+ RIDV + +G +R L+ + L P IALDP G +FF++ Q K+
Sbjct: 478 NKLYLVETKVNRIDVVNLEGNQRVTLITENLGHPRGIALDPTVGYLFFSDWGSLSGQPKV 537
Query: 1609 EAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGM 1788
E A MDG+NR+ LV T +GI +D+ +KRVYWVD + D +E++ Y G R+ VA+G
Sbjct: 538 ERAFMDGSNRKDLVTTKVGWPAGITLDLVSKRVYWVDSRYDYIETVTYDGIQRKTVARGG 597
Query: 1789 NVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQ 1968
++VPHPFG++LF++++++TDWT++ V++ KF ++ ++++ P G++ YH + Q
Sbjct: 598 SLVPHPFGISLFEEHVFFTDWTKMAVMKASKFTETNPQVYH--QSSLRPHGVTVYHALRQ 655
Query: 1969 PGPGQSECLAMKIENPC--TNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGK-RCID 2139
P NPC N C +C+LS G+GY+C C G +L + + RC+
Sbjct: 656 P----------NATNPCGSNNGGCAQVCVLSHRTDNGGLGYRCKCEFGFELDDDEHRCVA 705
Query: 2140 SIDYLLFSSNKIVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADI 2319
++LLFSS VRGI + ++P++ +G+ F D ++ FY+D+
Sbjct: 706 VKNFLLFSSKTAVRGI--PFTLSTQEDVMVPVTGSPSFFVGIDF----DAQHSTVFYSDL 759
Query: 2320 MDNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVH 2499
+ IY+ + DG G + + + ++FDWIS+ LY+ D S+ V+++ +
Sbjct: 760 SKDIIYKQKIDGTGKEVITANRLESVECLTFDWISRNLYWTDGGLKSVTVLRLADKS--- 816
Query: 2500 PDELVRRQLITELRDPVSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRP 2679
RRQ+I+ L +P S+VVHP G +F ++ RPA I R DG + I NT+LG P
Sbjct: 817 -----RRQIISNLNNPRSIVVHPTAGYMFLSDWFRPAKIMRAWSDGSHLMPIVNTSLGWP 871
Query: 2680 SEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVKLDIDNPI--PVAITIMNEYIYYVHQR 2853
+ +AID++ +RL W D I DG + +L + + P +T+ + ++ R
Sbjct: 872 NGLAIDWSASRLYWVDAFFDKIEHSTLDGLDRKRLGHVDQMTHPFGLTVFKDNVFITDWR 931
Query: 2854 PYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCF 3033
+I RV K +GG ++R S+ +KA Q + + C+ CF
Sbjct: 932 LGAIIRVRKSDGGDMTVIRR---GISSVMHVKAYDADLQTGSNYCSQTTHANGDCSHFCF 988
Query: 3034 ATPSESHPNELEAKCACRQGFMINKENNHSCQKDPA-EKIEQLCSSNSTQFQCKNGRCIP 3210
P+ + C C G + ++ +C+ DPA E Q C S S F C NG+C+P
Sbjct: 989 PVPN------FQRVCGCPYGMKLQRD-QMTCEGDPAREPPTQQCGSLS--FPCNNGKCVP 1039
Query: 3211 KEWKCDGENDCLDESDEIDEKGDKC--FHETECAENTIKCRNTKKCIPAQXXXXXXXXXX 3384
++CDG +DC D SDE +C F+ T C+ + C +CIP Q
Sbjct: 1040 SFFRCDGVDDCHDNSDE-----HQCGVFNNT-CSPSAFACVRGGQCIPGQWHCDRQND-- 1091
Query: 3385 XXXXXXVKYCKDGQ----------KPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEK 3534
C DG C + F CDNH CIP+ W EK
Sbjct: 1092 ---------CLDGSDEQNCPTHATSSTCPSTSFTCDNHVCIPKDWVCDTDNDCSDGSDEK 1142
Query: 3535 LEMCGNATCAANQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANG 3714
+ TC QF C + RCI ++CDGD DC DG+DE C + C++ QF+CA+G
Sbjct: 1143 -NCQASGTCQPTQFRCPDHRCISPLYVCDGDKDCADGSDE--AGC-VLNCTSAQFKCADG 1198
Query: 3715 RQCVPLRNHXXXXXXXXXXXXXXXXAVTAES-CTPDQFKCVSSGLCIPASWKXXXXXXXX 3891
C+ R C PD+F+C G CIP +W+
Sbjct: 1199 SSCINSRYRCDGVYDCRDNSDEAGCPTRPPGMCHPDEFQCQGDGTCIPNTWECDGHPDCI 1258
Query: 3892 XXSDEPKFGCTSGRQCSSDQFKCGNGRCILNNWLCDGENDCGDGSDESSERGCKTSMNAR 4071
SDE GC + CS F C NG CI W+CDG+NDC D SD E+ C T
Sbjct: 1259 HGSDE-HTGCVP-KTCSPTHFLCDNGNCIYKAWICDGDNDCRDMSD---EKDCPT--QPF 1311
Query: 4072 KCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCSFKCHNSPN 4251
CP C TCI L LCDG CP GTDE C +D CS GC+ +C P
Sbjct: 1312 HCPSTQWQCPG-YSTCINLSALCDGVFDCPNGTDESPLCNQDSCSHFNGGCTHQCMQGPF 1370
Query: 4252 GPICSCPFGEQLVNKTK-CEPENECLDSSSCSQRCKDEKHGFTCSCDEGYELDVDKRTCK 4428
G C CP G QL N TK CE NEC CSQ C + + F C+CD Y L+ D RTCK
Sbjct: 1371 GATCLCPLGYQLANDTKTCEDINECDIPGFCSQHCVNMRGSFRCACDPEYTLESDGRTCK 1430
Query: 4429 VADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGAIVEN---AIALAWDSLTDRIYWSDIRE 4599
V + ++ + V++R++I D+ + H ++V++ +AL +DS+T R++WSD+ +
Sbjct: 1431 VTGS-ENPLLVVASRDKIIV-DNITAHTHNLYSLVQDVSFVVALDFDSVTGRVFWSDLLQ 1488
Query: 4600 KKILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLL 4779
K S +NGT+ V GL +TE IA+DW+GRNLYW D +L TIEV+ + D RT+L
Sbjct: 1489 GKTWSVFQNGTDKRVVHDSGLSVTEMIAVDWIGRNLYWTDYALETIEVSKI-DGSHRTVL 1547
Query: 4780 VHQNVSQPRGIAVDPRKG--VMFWTDWGQNPCIERASMDGTDRQIIVKTKIYWPNTIALD 4953
+ +NV++PRG+A+DPR G VMFW+DWG +P IERASMDGT R +IV+ KIYWP +++D
Sbjct: 1548 ISKNVTKPRGLALDPRMGDNVMFWSDWGHHPRIERASMDGTMRTVIVQEKIYWPCGLSID 1607
Query: 4954 YTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQ 5133
Y +YF D+ LD+I+F +YDG R QV+AS + HPHAL +FED +Y++DR +++
Sbjct: 1608 YPNRLIYFMDAYLDYIEFCDYDGHNRRQVIASDLVLHHPHALTLFEDFVYWTDRGTRQVM 1667
Query: 5134 VYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTNPCSHLCLLNNK--NTFT 5307
K+ G S ++ + LG+ A+HP QP NPC++ CSHLCLL+ + ++
Sbjct: 1668 QANKWHGGNQS-VVMYSVHQPLGITAIHPSRQPP-SRNPCASASCSHLCLLSAQAPRHYS 1725
Query: 5308 CKCPMGEKLDASGKKCIDDAKPFLVIIQKTNVFGIEMNSASEKETPVLAGMVPLSGLGNA 5487
C CP G L C+ +PFL+ ++ +FGI + + E MVP+SG+ +
Sbjct: 1726 CACPSGWNLSDDSVNCVRGDQPFLMSVRDNIIFGISL----DPEVKSNDAMVPISGIQHG 1781
Query: 5488 FDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNGGNKTKMFSSAVPDDAYCLGF 5667
+D +D + ++ +E+ I+R +G N+T ++ + L
Sbjct: 1782 YDVEFDDSEQFIYWVENPGE------------IHRVKTDGSNRTVFAPLSLLGSSLGLAL 1829
Query: 5668 DWNGRNLVVGNKITQTIEIIRTQG-KQYRSVILSNDQSXXXXXXXXXXXXXXXKGYVFWL 5844
DW RN+ +++IE++ +G +Y +++ND + +G ++W
Sbjct: 1830 DWVSRNIYYTTPASRSIEVLTLKGDTRYGKTLIANDGTPLGVGFPVGIAVDPARGKLYWS 1889
Query: 5845 DRG-GGAADAKVARAGLDGSNPLVIASNDLAELDHIAIDTTNTRVYFSEAKAGRISSVTY 6021
D G AK+A A +DG++ ++ + +L L+ + +D ++Y++ G I
Sbjct: 1890 DHGTDSGVPAKIASANMDGTSLKILFTGNLQHLEVVTLDIQEQKLYWAVTSRGVIERGNV 1949
Query: 6022 DGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAFDSIE-VATINGDSQPPQWTHFKKDVEN 6198
DG +R +L P GL YG L+Y+D ++ IE V +G+++ + +V
Sbjct: 1950 DGTER-MILVHHLAHPWGLVVYGSFLYYSDEQYEVIERVDKSSGNNK----VVLRDNVPY 2004
Query: 6199 LANIKALQPR-ASSSGHPCHINNGNCDHICIPLMFAQRTCTCANGY--VKDGQTSCKLFD 6369
L ++ R A+ S + C N C IC+P+ +C CA+G+ DG+ SC ++
Sbjct: 2005 LRGLRVYHRRNAADSSNGCSNNPNACQQICLPVPGGMFSCACASGFKLSPDGR-SCSPYN 2063
Query: 6370 ESFVIVATKTKVIGYPIDETQSKGVAMEPIG--GLSITGVDYDYESKTIYVAEASG---I 6534
SF++V+ V G+ + E AM P+ G ++ D D + IY + S
Sbjct: 2064 -SFMVVSMLPAVRGFSL-ELSDHSEAMVPVAGQGRNVLHADVDVANGFIYWCDFSSSVRS 2121
Query: 6535 NKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINYNMYFINHDAERTNIEVSKLDGTY 6714
+ GI S+ V+ IG+ I+ +A+DW N+YF N T IEV +++ TY
Sbjct: 2122 SNGIRRIKPDGSNFTNVVTYGIGANGIRGVALDWAAGNLYFTNAFVYETLIEVLRINTTY 2181
Query: 6715 RKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLV 6894
R++LL + P I VDP RYL+WAD GQKP I+RSFLD + R V+VS GI P L
Sbjct: 2182 RRVLLKVSVDMPRHIIVDPKHRYLFWADYGQKPKIERSFLDCTNRTVLVSEGIVTPRGLA 2241
Query: 6895 VDVASKMIYWSDAKMDGIYRVRSTGGTPELVR--SDIASAAGVALHGQNMYWTDNRLEKL 7068
+D + IYW D +D I R+ GG ++VR S + G+ + G+++ W D L+K+
Sbjct: 2242 MDHDTGYIYWVDDSLDLIARIHLDGGESQVVRYGSRYPTPYGITVFGESIIWVDRNLKKV 2301
Query: 7069 FRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRASSPCQITDN---LRKSPCTQ 7239
F+A+ +P T P + + + DV +F + QP SP ++ +N C+
Sbjct: 2302 FQASKQPGNTD---PPVVIRDKINLLRDVTIFDEHAQP--LSPAELNNNPCLQSNGGCSH 2356
Query: 7240 LCFATPGTQTPTCSCARGVL--KGRTC-EEPDTYIMFSDGDKIIDVAIEPDVKASRPLKD 7410
CFA P TP C CA G L G++C + ++++S + + + +P R
Sbjct: 2357 FCFALPELPTPRCGCAFGTLGNDGKSCATSQEDFLIYSLNNSLRSLHFDP-----RDHSL 2411
Query: 7411 PFPEISNLQT---FDVDVNLRRVYFVVE-SPVGVNISWFSMNNAENPRLVFGASKQPHAK 7578
PF IS T D D R++F + + + IS+ S+ + + V
Sbjct: 2412 PFQVISVAGTAIALDYDRRNNRIFFTQKLNSLRGQISYVSLYSGSSSPTVL-------LS 2464
Query: 7579 EIRHISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTIASGDWTYALAIDPCSGLLFW 7758
I + DW+ ++IY++ + ++ G + + IA A+ +DPC G ++W
Sbjct: 2465 NIGVTDGIAFDWINRRIYYSDFSNQTINSMAEDGSNRAVIARVSKPRAIVLDPCRGYMYW 2524
Query: 7759 SDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVDFRNQKIYWADVNRLNIE 7938
+D G +IER+ L G R IV+ S+ P +A+D +YWAD + IE
Sbjct: 2525 TDWGTNA-------KIERATLGGNFRVPIVNTSLVWPNGLALDLETDLLYWADASLQKIE 2577
Query: 7939 VADYDGQNRKVIAS-GYRAKSLDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVSDRRIP 8115
+ G NR+V+ S + + L ++ +++Y +D + ++R +K GS L V R+P
Sbjct: 2578 RSTLTGTNREVVVSTAFHSFGLTVYGQYIYWTDLYTRKIYRANKYDGSDL--VAMTTRLP 2635
Query: 8116 GALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLCTVVADDIGLAASKVQCSCNDTY 8295
+ + V+T+ Q C S C NGGC +C G ++ QC +
Sbjct: 2636 --TQPSGISTVVKTQRQQC----SNPCDQFNGGCSHICAP-----GPNGAECQCPHEGNW 2684
Query: 8296 ELVQEPGKDYPTQCVLRGSNSEPAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDEN 8475
L + CV+ + C F C +G CI CD+ DC D SDE
Sbjct: 2685 YLAND-----NKYCVV-----DTGTRC-NQLQFTCLNGHCINQDWKCDNDNDCGDGSDEL 2733
Query: 8476 PNYCNTRSCPEDYNLCTNRRCIDSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCSNGH 8655
P C +C C N RC+ +C++ +DCGD SDE C + F CSNG
Sbjct: 2734 PTVCAFHTCRSTAFTCGNGRCVPYHYRCDYYNDCGDNSDEAGCLFRNCNSTTEFTCSNGR 2793
Query: 8656 CINQTKVCDGHNDCHDEQVSDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDC 8835
CI + VC+G N+CHD SDE CP P C +C TNIC+ A LCDG +DC
Sbjct: 2794 CIPLSYVCNGINNCHDNDTSDEK--NCP--PHTCPPDFTKCQTTNICVPRAFLCDGDNDC 2849
Query: 8836 GDKADENQLFCMNQQCAQHYVRCPS-GRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKK 9012
GD +DEN ++C + C + +C S RCIP W CDG+ DC+DG DE DT G
Sbjct: 2850 GDGSDENPIYCASHTCRSNEFQCLSPQRCIPSYWFCDGEADCADGSDE-----PDTCGHS 2904
Query: 9013 I--CVGDYLFQCDNLKCISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKL 9186
+ C FQCDN +CIS ++ RH C + C+ +F C ++
Sbjct: 2905 VNTCRASQ-FQCDNGRCISGNWVCDGDNDCGDMSDEDQRHHCELQNCSSTQFTCVNS--- 2960
Query: 9187 AQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECNKGEFRCSNQHCIHSTWECDGD 9366
P CIP+ W+CDGD C+ D EL + C+ GEF C+N C+ ++ CD
Sbjct: 2961 RPPNRRCIPQYWVCDGDADCS---DALDELQNCTMRTCSAGEFSCANGRCVRQSFRCDRR 3017
Query: 9367 NDCLDGSDEHANCTYSSCQPDFFQCANHKCVPNSWKCDGNDDCEDGSDEKDCPKNSASAQ 9546
NDC D SDE C+Y C + F C N +C+P + CD ++DC DGSDE++
Sbjct: 3018 NDCGDYSDER-GCSYPPCHANQFTCQNGRCIPRFFVCDEDNDCGDGSDEQE----HLCHT 3072
Query: 9547 KASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCMDM 9726
C QF+C +G CI+ +VC+ DC+D SDE C I+EC + C+ C D
Sbjct: 3073 PEPTCPLHQFRCDNGHCIEMGRVCNHVDDCSDNSDEKG-CGINECLDSSISRCDHNCTDT 3131
Query: 9727 KIGYKCDCFEGFAIDISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDD 9906
+ C C G+ + +SD++SC +++EC E CSQKC++ +GSY C C GY D
Sbjct: 3132 ITSFYCSCLPGYKL-MSDKRSCVDIDECKESPQLCSQKCENVVGSYICKCAPGYIREPDG 3190
Query: 9907 HSCKRTEMEPEPFFLLANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLIDQG 10086
SC R EP+ + +N++YIR ++ DG+ Y L QG NVV+LD D EK+ Y ID
Sbjct: 3191 KSC-RQNSNIEPYLIFSNRYYIRNLTTDGSSYSLILQGLGNVVALDFDRVEKRLYWIDAE 3249
Query: 10087 KLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGR 10266
K + R+ L++ ++ ET++ H + E +AVDWV RKLY L+ + V +L+GR
Sbjct: 3250 KQIIERMFLNK-----TNRETIINHRLRRAESLAVDWVSRKLYWLDAILDCLFVSDLEGR 3304
Query: 10267 FCKTLIRDRI--------QQPKAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIF 10422
K + + + + P+ IV+HP +G++++ +W + YIGRI +DG+ +
Sbjct: 3305 HRKMIAQHCVDANNTFCFEHPRGIVLHPQRGHVYWADWGVHAYIGRIGMDGTNK-----S 3359
Query: 10423 KLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVVFD 10602
+ + WPNAI IDY +D L+W DAHL I F D +G+ R + H ++ +F+
Sbjct: 3360 VIISTKIEWPNAITIDYTNDLLYWADAHLGYIEFSDLEGHHRHTVYDGSLPHPFALTIFE 3419
Query: 10603 DYLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGCS 10782
D ++W DWN R V + +K+ G +L T P D+ + HP RQP NPCG NNGGCS
Sbjct: 3420 DTVFWTDWNTRTVEKGNKYDGSGRVVLVNTTHKPFDIHVYHPYRQPIMSNPCGTNNGGCS 3479
Query: 10783 HLCLIGAGGNGYTCSCPDQF--VLLSDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEP 10956
HLCLI AGG G+TC+CPD F V L D+ C P C+ QF CG ++ KCIP W CDG+
Sbjct: 3480 HLCLIKAGGRGFTCACPDDFQTVQLRDRTLCMPMCSSTQFLCGNNE-KCIPIWWKCDGQK 3538
Query: 10957 DCRDGSDEPGESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXXEQN--CD-KAC 11127
DC DGSDEP +C R C +G+FQC + NCT P + E C+ C
Sbjct: 3539 DCSDGSDEP--DLCPHRFCRLGQFQCRDGNCTSPQALCNARQDCADGSDEDRVLCEHHRC 3596
Query: 11128 DPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEADTLCMSAERNCTAEEFRCNNNKCIAKA 11307
+ ++C A RCIP+ + SDE + C A R C +F+CNN +CI ++
Sbjct: 3597 ESNEWQC-ANKRCIPQSWQCDSVNDCLDNSDEDTSHC--ASRTCRPGQFKCNNGRCIPQS 3653
Query: 11308 WRXXXXXXXXXXXXE-TPEC--AQIECKKGWT-RCSSSYRCIPNWAFCNGQDDCRDNSDE 11475
W+ E EC A C C ++YRCIP WA CNG DDCRDNSDE
Sbjct: 3654 WKCDVDNDCGDYSDEPIDECTTAAYNCDNHTEFSCKTNYRCIPQWAVCNGFDDCRDNSDE 3713
Query: 11476 DKQRCPTCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRC 11655
C G+FRCA + CIP RW CD +DCGDNSDE + R CSESEFRC
Sbjct: 3714 QGCESVPCHPSGDFRCA-NHHCIPLRWKCDGTDDCGDNSDEENC----VPRECSESEFRC 3768
Query: 11656 NDGKCIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNA 11835
D +CIP VCD C D DE C ++ C P H QC G C+ + CD + DC +A
Sbjct: 3769 ADQQCIPSRWVCDQENDCGDNSDERDCEMKTCHPEHFQCTSGHCVPKALACDGRADCLDA 3828
Query: 11836 ADELHCED--VSRRTCSPFEFECANSVCIPRKFMXXXXXXXXXXSDETSSECRSAQCDPP 12009
+DE C + C FEC N VCI ++ SDE C + C+ P
Sbjct: 3829 SDESACPTRFPNGTYCPAAMFECKNHVCIQSFWICDGENDCVDGSDEEIHLCFNIPCESP 3888
Query: 12010 LRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSFSEYGDCSSDQFKCANGKCVN 12189
RFRC +SR C+ QLCNG +DCG D SDE C + C+ ++KC+NG C++
Sbjct: 3889 QRFRCDNSR-CVYGHQLCNGVDDCG--DGSDEKEEHCRK-PTHKPCTDTEYKCSNGNCIS 3944
Query: 12190 GTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKHICTDVRD-GFYCHCRDGFRP 12366
CD +DCGD SDE GC+ +T E C+ CT + GF C CR GF+P
Sbjct: 3945 QHYVCDNVNDCGDLSDETGCNLGDNRTCAENI-----CEQNCTQLSSGGFICSCRPGFKP 3999
Query: 12367 DPQSPKECIDIDECAGNNTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAA 12546
C DI+EC C Q C N+KGSY C C + +++ + + G+ C A G
Sbjct: 4000 STSDKNSCQDINECEEFGICPQSCRNSKGSYECFCVDGFKS---MSTHYGERCAADGSPP 4056
Query: 12547 NVMIGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXXXXPRK---ELMYW---IDGSE 12708
+++ + V++ + + + + P ++Y+ GS+
Sbjct: 4057 LLLLPEN---VRIRKYNTSSEKFSEYLEEEEHIQTIDYDWDPEHIGLSVVYYTVLAQGSQ 4113
Query: 12709 -RTIYRSAIANGNQSHEGQKLDVDFAAMGVV-PTAIAVDYTTGNLFIA-AVSENIENGLV 12879
I R+ I N +VD ++ P +AVD+ +++ + A S+ IE
Sbjct: 4114 FGAIKRAYIPNFESGSNNPIREVDLGLKYLMQPDGLAVDWVGRHIYWSDAKSQRIE---- 4169
Query: 12880 TARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLH 13059
V DGRY K ++ L QP A+ P G + ++D G
Sbjct: 4170 --------------------VATLDGRYRKWLITTQLDQPAAIAVNPKLGLMFWTDQGKQ 4209
Query: 13060 AKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTV 13239
KIE A M+G HR ++V + + P ++ID +R+YW D K ++A+ DG++R +
Sbjct: 4210 PKIESAWMNGEHRSVLVSENLGWPNGLSIDYLNDDRVYWSDSKEDVIEAIKYDGTDRRLI 4269
Query: 13240 VHDRHIPYAVDVFENHIYWLSRESKTLYVQDKFGRGR------VSVLASDLEDGHTVRVS 13401
+++ P+++D+FE+ +YW+++E ++ Q+KFG+ V+ + + H +R +
Sbjct: 4270 INEAMKPFSLDIFEDKLYWVAKEKGEVWRQNKFGKENKEKVLVVNPWLTQVRIFHQLRYN 4329
Query: 13402 QKYAKDTQRTVSGCERAQCSHLCVSLPSTGFACLCPDG--IVPQLDGSCATQHVEALTMP 13575
Q +VS + CSHLC+ P G++C CP G V C +TMP
Sbjct: 4330 Q--------SVSNPCKQVCSHLCLLRPG-GYSCACPQGSDFVTGSTVQCDAASELPVTMP 4380
Query: 13576 KQCKCTNGGKCRLDGS----CECTSDFEGDQCEKESSVSRKI-IGTLSENFIT------V 13722
C+C +GG C D + C+C+S + G+ C E +SR I GT +T V
Sbjct: 4381 PPCRCMHGGNCYFDENELPKCKCSSGYSGEYC--EVGLSRGIPPGTTMAVLLTFVIVIIV 4438
Query: 13723 XXXXXXXXXXXXXXXXXXXNLYKRRQL--LFKKNEAADG-------SVSFHGNVISFSNP 13875
L K L L K +E +G V+ V F
Sbjct: 4439 GALVLVGLFHYRKTGSLLPTLPKLPSLSSLAKPSENGNGVTFRSGADVNMDIGVSPFGPE 4498
Query: 13876 VLENKQDAPGSEFNMQQMTSMHDDSTTFTNPVYELEDVDMSSPPPSNDQPSTSASAMSPN 14055
+ ++ A F M+ + F NP+Y +D +TS A++
Sbjct: 4499 TIIDRSMAMNEHFVME----VGKQPVIFENPMYAAKD-------------NTSKVALAVQ 4541
Query: 14056 RPSTSAASSFVPPTFDQDEIELKTADEIIVPKAEISKPPIPARP-------------KKE 14196
PST A + VP + +E + I P +EI P PA P K++
Sbjct: 4542 GPSTGAQVT-VP-----ENVENQNYGRPIDP-SEIVPEPKPASPGADEIQGKKWNIFKRK 4594
Query: 14197 KADPLRVDNPLY-DPDSEVSD 14256
+NP+Y + DSEV D
Sbjct: 4595 PKQTTNFENPIYAEMDSEVKD 4615
Score = 432 bits (1110), Expect = e-118
Identities = 306/1021 (29%), Positives = 464/1021 (44%), Gaps = 25/1021 (2%)
Frame = +1
Query: 139 NTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPG-CKSDQWQCDTYTWH 315
+ SS C F C++ CI +W G C+ Q++C +
Sbjct: 1104 HATSSTCPSTSFTCDNHVCIPKDWVCDTDNDCSDGSDEKNCQASGTCQPTQFRCPDH--- 1160
Query: 316 SVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDC 495
CI+ CD DCADGSDE C ++C+S F CADG C + +CDG YDC
Sbjct: 1161 --RCISPLYVCDGDKDCADGSDEAGC---VLNCTSAQ-FKCADGSSCINSRYRCDGVYDC 1214
Query: 496 RDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTA 675
RD SDE +R C +F+C CI +W CDG DC GSDE C K C+
Sbjct: 1215 RDNSDEAGCPTRPPGMCHPDEFQCQGDGTCIPNTWECDGHPDCIHGSDEHTGCVPKTCSP 1274
Query: 676 NEFQCKNKRCQPRKFRCDYYDDCGDNSDEDEC--GEYRCPPGKWNCPGTGHCIDQLKLCD 849
F C N C + + CD +DC D SDE +C + CP +W CPG CI+ LCD
Sbjct: 1275 THFLCDNGNCIYKAWICDGDNDCRDMSDEKDCPTQPFHCPSTQWQCPGYSTCINLSALCD 1334
Query: 850 GSKDCADGADEQQ-CSQNLCPSL--GCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDIN 1020
G DC +G DE C+Q+ C GC C P G C CP GY+L + +TC DIN
Sbjct: 1335 GVFDCPNGTDESPLCNQDSCSHFNGGCTHQCMQGPFGATCLCPLGYQLAND-TKTCEDIN 1393
Query: 1021 ECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVA 1200
EC G+C Q C N R F C+C + +TL+ D T C ++ L VA
Sbjct: 1394 ECDIPGFCSQHCVNMRGSFRCACDPE-YTLE------SDGRT----CKVTGSENPLLVVA 1442
Query: 1201 RREGLYRLNPKNPDEEVKKLASG-EFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEI 1377
R+ + N + L F+ +DFD ++FW+D L +S V G
Sbjct: 1443 SRDKIIVDNITAHTHNLYSLVQDVSFVVALDFDSVTGRVFWSDLLQGKTWS--VFQNGTD 1500
Query: 1378 SQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDI 1557
++ S L +AVDWI LY + I+VS DG RTVL++ +T P +
Sbjct: 1501 KRVVHDS--GLSVTEMIAVDWIGRNLYWTDYALETIEVSKIDGSHRTVLISKNVTKPRGL 1558
Query: 1558 ALDPLRGE--MFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDP 1722
ALDP G+ MF++ + ++E A+MDGT R +V + G+ +D + +Y++D
Sbjct: 1559 ALDPRMGDNVMFWSDWGHHPRIERASMDGTMRTVIVQEKIYWPCGLSIDYPNRLIYFMDA 1618
Query: 1723 KVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKF--GSDT 1896
+D +E DY G++RR V V+ HP L LF+ ++YWTD V+Q K+ G+ +
Sbjct: 1619 YLDYIEFCDYDGHNRRQVIASDLVLHHPHALTLFEDFVYWTDRGTRQVMQANKWHGGNQS 1678
Query: 1897 KLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFG 2076
+++S + P+GI+A HP QP NPC +A C +C+LS
Sbjct: 1679 VVMYSVHQ----PLGITAIHPSRQP----------PSRNPCASASCSHLCLLSAQAPRH- 1723
Query: 2077 VGYKCACPIGQKLVNGK-RCI-DSIDYLLFSSNKIVRGIF--PEINEKALAEAVLPISPI 2244
Y CACP G L + C+ +L+ + I+ GI PE+ +A++PIS I
Sbjct: 1724 --YSCACPSGWNLSDDSVNCVRGDQPFLMSVRDNIIFGISLDPEVKSN---DAMVPISGI 1778
Query: 2245 SQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGA---APVLVTHNDGLFSMSFD 2415
++VE D F Y I+R++ DG AP+ + + ++ D
Sbjct: 1779 QHG-----YDVEFD-DSEQFIYWVENPGEIHRVKTDGSNRTVFAPLSLLGSS--LGLALD 1830
Query: 2416 WISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKGLLFYA- 2592
W+S+ +YY S+EV+ + + + PV + V P +G L+++
Sbjct: 1831 WVSRNIYYTTPASRSIEVLTLKGDTRYGKTLIANDGTPLGVGFPVGIAVDPARGKLYWSD 1890
Query: 2593 ---EAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFD 2763
++ PA I ++DG + +++ L + +D E +L W T I + D
Sbjct: 1891 HGTDSGVPAKIASANMDGTSLKILFTGNLQHLEVVTLDIQEQKLYWAVTSRGVIERGNVD 1950
Query: 2764 GKNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFS 2943
G + L P + + ++YY ++ I RV K +G ++R+ + +
Sbjct: 1951 GTERMILVHHLAHPWGLVVYGSFLYYSDEQYEVIERVDKSSGNNKVVLRD---NVPYLRG 2007
Query: 2944 LKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINKENNHS 3123
L+ +N D S + C Q+C P CAC GF ++ + S
Sbjct: 2008 LRVYHRRN--AADSSNGCSNNPNACQQICLPVPGGMF------SCACASGFKLSPD-GRS 2058
Query: 3124 C 3126
C
Sbjct: 2059 C 2059
Score = 404 bits (1039), Expect = e-110
Identities = 288/1039 (27%), Positives = 454/1039 (42%), Gaps = 97/1039 (9%)
Frame = +1
Query: 3535 LEMCGNATCAANQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANG 3714
LE + C + F C NG CIP W CDG DC D TDE CPP C + F C
Sbjct: 20 LEPVSSQECGSGNFRCDNGYCIPASWRCDGTRDCLDDTDE--IGCPPRSCESGLFLCPAE 77
Query: 3715 RQCVPLRNHXXXXXXXXXXXXXXXXAVTAESCTPDQFKCVSSGLCIPASWKXXXXXXXXX 3894
C+P + +C+ Q C S+G CIP+ ++
Sbjct: 78 GTCIP-SSWVCDEDKDCSDGADEQQNCAGTTCSAQQMTC-SNGQCIPSEYRCDHVSDCPD 135
Query: 3895 XSDE--------PKFGCTSG-------------------------RQCSSDQFKCGNGRC 3975
SDE + C +G CS +F+CG+G C
Sbjct: 136 GSDERNCHYPTCDQLTCANGACYNTSQRCDQKVDCRDSSDEANCTTLCSQKEFECGSGEC 195
Query: 3976 ILNNWLCDGENDCGDGSDE------------------------------------SSERG 4047
IL ++CD +NDC D SDE E G
Sbjct: 196 ILRAYVCDHDNDCEDNSDERNCNYDTCGGHQFTCSNGQCINQNWVCDGDDDCQDSGDEDG 255
Query: 4048 CKTSMNARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDE-----GGRCARDLCSAD 4212
C+++ + +C AC CI + ++CDG CP G DE G C +CS
Sbjct: 256 CESNQSHHRCYPREWACPGSGR-CISIDKVCDGVPDCPEGDDENNVTSGRTCGMGVCSV- 313
Query: 4213 RAGCSFKCHNSPNGPICSCPFGEQLVNKT---KCEPENECLDSSSCSQRCKDEKHGFTCS 4383
C ++CH +P G C CP G ++N C ++C C Q+C++ + C
Sbjct: 314 -LNCEYQCHQTPFGGECFCPPG-HIINSNDSRTCIDFDDCQIWGICDQKCENRQGRHQCL 371
Query: 4384 CDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGAIVENAIALAWD- 4560
C+EGY L+ + CK +D+ + SN + D N+ + + D
Sbjct: 372 CEEGYILERGQH-CKSSDSFSAASVIFSNGRDLLVGDLHGRNFRILAESKNRGMVMGVDF 430
Query: 4561 -SLTDRIYWSDIREKKILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVDSSLNTI 4737
R++W+D ++K+ S + NG N + +D E +A+DW+ LY V++ +N I
Sbjct: 431 HYQKHRVFWTDPMQEKVFSTDINGLNTQEILNVSVDTPENLAVDWINNKLYLVETKVNRI 490
Query: 4738 EVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQ---NPCIERASMDGTDRQI 4908
+V NLE QR L+ +N+ PRGIA+DP G +F++DWG P +ERA MDG++R+
Sbjct: 491 DVVNLEG-NQRVTLITENLGHPRGIALDPTVGYLFFSDWGSLSGQPKVERAFMDGSNRKD 549
Query: 4909 IVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIF 5088
+V TK+ WP I LD + RVY+ DS+ D+I+ V YDG R V V HP +++F
Sbjct: 550 LVTTKVGWPAGITLDLVSKRVYWVDSRYDYIETVTYDGIQRKTVARGGSLVPHPFGISLF 609
Query: 5089 EDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTN-- 5262
E+ ++++D + K+ Y + + GV H + QP NPC +N
Sbjct: 610 EEHVFFTDWTKMAVMKASKFTETNPQVYHQSSL-RPHGVTVYHALRQP-NATNPCGSNNG 667
Query: 5263 PCSHLCLLNNKNT-----FTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNVFGIEMNSA 5427
C+ +C+L+++ + CKC G +LD +C+ K FL+ KT V GI +
Sbjct: 668 GCAQVCVLSHRTDNGGLGYRCKCEFGFELDDDEHRCV-AVKNFLLFSSKTAVRGIPFTLS 726
Query: 5428 SEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNG 5607
++++ V P +G FDA H+ + IY+ ++G
Sbjct: 727 TQEDVMVPVTGSPSFFVGIDFDA---------------QHSTVFYSDLSKDIIYKQKIDG 771
Query: 5608 GNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVI--LSNDQSX 5781
K + ++ + + CL FDW RNL + +++ ++R K R +I L+N +S
Sbjct: 772 TGKEVITANRL-ESVECLTFDWISRNLYWTDGGLKSVTVLRLADKSRRQIISNLNNPRSI 830
Query: 5782 XXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAIDT 5961
GY+F D AK+ RA DGS+ + I + L + +AID
Sbjct: 831 VVHPTA---------GYMFLSD---WFRPAKIMRAWSDGSHLMPIVNTSLGWPNGLAIDW 878
Query: 5962 TNTRVYFSEAKAGRISSVTYDGQDRHYV-LSDGGRQPNGLAFYGDRLFYADSAFDS-IEV 6135
+ +R+Y+ +A +I T DG DR + D P GL + D +F D + I V
Sbjct: 879 SASRLYWVDAFFDKIEHSTLDGLDRKRLGHVDQMTHPFGLTVFKDNVFITDWRLGAIIRV 938
Query: 6136 ATINGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHIN---NGNCDHICIPLMFAQ 6306
+G T ++ + ++ ++KA + + C NG+C H C P+ Q
Sbjct: 939 RKSDGGDM----TVIRRGISSVMHVKAYDADLQTGSNYCSQTTHANGDCSHFCFPVPNFQ 994
Query: 6307 RTCTCANGY-VKDGQTSCK 6360
R C C G ++ Q +C+
Sbjct: 995 RVCGCPYGMKLQRDQMTCE 1013
Score = 342 bits (877), Expect = 2e-91
Identities = 224/771 (29%), Positives = 350/771 (45%), Gaps = 13/771 (1%)
Frame = +1
Query: 8596 LDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPGLPIDCRGVKVR 8775
L+ S+ C G F C NG+CI + CDG DC D+ +DE CP P C
Sbjct: 20 LEPVSSQECGSGNFRCDNGYCIPASWRCDGTRDCLDD--TDE--IGCP--PRSCESGLFL 73
Query: 8776 CPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCIPETWQCDGDND 8955
CP CI + +CD DC D ADE Q C C+ + C +G+CIP ++CD +D
Sbjct: 74 CPAEGTCIPSSWVCDEDKDCSDGADEQQ-NCAGTTCSAQQMTCSNGQCIPSEYRCDHVSD 132
Query: 8956 CSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXXXXXXHSRHGCG 9135
C DG DE NC + CD L C + A S
Sbjct: 133 CPDGSDE--RNC------------HYPTCDQLTCANGACYNTSQRCDQKVDCRDSSDEAN 178
Query: 9136 NRT-CTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECNKGE 9312
T C+ +EF C S ECI RA++CD D C DE C + C +
Sbjct: 179 CTTLCSQKEFECGSG--------ECILRAYVCDHDNDCEDNSDERN--CNYD--TCGGHQ 226
Query: 9313 FRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCANHKCVPNSWKCDGNDD 9492
F CSN CI+ W CDGD+DC D DE C+ + ++H+C P W C G+
Sbjct: 227 FTCSNGQCINQNWVCDGDDDCQDSGDE------DGCESN---QSHHRCYPREWACPGSGR 277
Query: 9493 CEDGSDEKDCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLCFI 9672
C S +K C +G C G+ D N + R+ +C +
Sbjct: 278 CI--SIDKVC--------------DGVPDCPEGD--------DENNVTSGRTCGMGVCSV 313
Query: 9673 DECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNEC-YEGISGCSQKCDD 9849
C E +C G +C C G I+ +D ++C + ++C GI C QKC++
Sbjct: 314 LNC--------EYQCHQTPFGGECFCPPGHIINSNDSRTCIDFDDCQIWGI--CDQKCEN 363
Query: 9850 KIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYELAAQGFDN 10029
+ G ++C C +GY L H CK ++ + +N + + G + + A+ +
Sbjct: 364 RQGRHQCLCEEGYILERGQH-CKSSDSFSAASVIFSNGRDLLVGDLHGRNFRILAESKNR 422
Query: 10030 --VVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDWVG 10203
V+ +D + + + D + ++ D++ +++ + +L +V E +AVDW+
Sbjct: 423 GMVMGVDFHYQKHRVFWTDPMQEKVFSTDINGLNT-----QEILNVSVDTPENLAVDWIN 477
Query: 10204 RKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFFTEW---SLQPYI 10374
KLY++ + I V L+G TLI + + P+ I + P GYLFF++W S QP +
Sbjct: 478 NKLYLVETKVNRIDVVNLEGNQRVTLITENLGHPRGIALDPTVGYLFFSDWGSLSGQPKV 537
Query: 10375 GRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRH 10554
R +DGS L +GWP I +D S R++W D+ + I + +DG R+
Sbjct: 538 ERAFMDGSNRKD-----LVTTKVGWPAGITLDLVSKRVYWVDSRYDYIETVTYDGIQRKT 592
Query: 10555 IP--AQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDLRIVHP 10728
+ H + +F++++++ DW V++ K+T N + ++ P+ + + H
Sbjct: 593 VARGGSLVPHPFGISLFEEHVFFTDWTKMAVMKASKFTETNPQVYHQSSLRPHGVTVYHA 652
Query: 10729 MRQPAYPNPCGDNNGGCSHLCLIG----AGGNGYTCSCPDQFVLLSDQKTC 10869
+RQP NPCG NNGGC+ +C++ GG GY C C F L D+ C
Sbjct: 653 LRQPNATNPCGSNNGGCAQVCVLSHRTDNGGLGYRCKCEFGFELDDDEHRC 703
Score = 285 bits (729), Expect = 2e-74
Identities = 213/694 (30%), Positives = 302/694 (42%), Gaps = 32/694 (4%)
Frame = +1
Query: 139 NTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHS 318
N C+E++FRC D +CI + W
Sbjct: 3755 NCVPRECSESEFRCADQQCIPSRWV----------------------------------- 3779
Query: 319 VSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCR 498
CD DC D SDE+DC T C ++ F C G C + CDG+ DC
Sbjct: 3780 ---------CDQENDCGDNSDERDCEMKT--CHPEH-FQCTSG-HCVPKALACDGRADCL 3826
Query: 499 DLSDEKDSCSR--NHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEP-DTCEFKKC 669
D SDE +R N T C F C + CIQ W+CDG DC DGSDE C C
Sbjct: 3827 DASDESACPTRFPNGTYCPAAMFECKNHV-CIQSFWICDGENDCVDGSDEEIHLCFNIPC 3885
Query: 670 -TANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDE--CGE---YRCPPGKWNCPGTGHCID 831
+ F+C N RC C+ DDCGD SDE E C + C ++ C G+CI
Sbjct: 3886 ESPQRFRCDNSRCVYGHQLCNGVDDCGDGSDEKEEHCRKPTHKPCTDTEYKC-SNGNCIS 3944
Query: 832 QLKLCDGSKDCADGADEQQCS---QNLCPSLGCQAGCHPSPHGG-ECTCPSGYKLDDRFH 999
Q +CD DC D +DE C+ C C+ C GG C+C G+K
Sbjct: 3945 QHYVCDNVNDCGDLSDETGCNLGDNRTCAENICEQNCTQLSSGGFICSCRPGFKPSTSDK 4004
Query: 1000 RTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNAD 1179
+C DINEC EFG C Q C N + + C C+ ++ +G C ++ +
Sbjct: 4005 NSCQDINECEEFGICPQSCRNSKGSYECFCVDGFKSMSTHYGE---------RCAADGSP 4055
Query: 1180 KMKLFVARREGLYRLNPKNPDEE--VKKLASGEFIYGIDFDY-----GDRKIFWTDRLAH 1338
+ L R+ N E + L E I ID+D+ G +++T
Sbjct: 4056 PLLLLPEN----VRIRKYNTSSEKFSEYLEEEEHIQTIDYDWDPEHIGLSVVYYTVLAQG 4111
Query: 1339 SAFSA------DVDDEGEISQIKK--LSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVS 1494
S F A + G + I++ L LK L+ P LAVDW+ +Y ++ S+RI+V+
Sbjct: 4112 SQFGAIKRAYIPNFESGSNNPIREVDLGLKYLMQPDGLAVDWVGRHIYWSDAKSQRIEVA 4171
Query: 1495 SYDGERRTVLLADGLTLPLDIALDPLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHTH 1665
+ DG R L+ L P IA++P G MF+T+ Q K+E+A M+G +R LV+ +
Sbjct: 4172 TLDGRYRKWLITTQLDQPAAIAVNPKLGLMFWTDQGKQPKIESAWMNGEHRSVLVSENLG 4231
Query: 1666 QVSGIVVD-ITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYW 1842
+G+ +D + RVYW D K D +E+I Y G DRR++ +N PF L +F+ LYW
Sbjct: 4232 WPNGLSIDYLNDDRVYWSDSKEDVIEAIKYDGTDRRLI---INEAMKPFSLDIFEDKLYW 4288
Query: 1843 TDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCT 2022
+ V + KFG + K N + + +H + + NPC
Sbjct: 4289 VAKEKGEVWRQNKFGKENK--EKVLVVNPWLTQVRIFHQLR---------YNQSVSNPCK 4337
Query: 2023 NADCEGMCILSKDNGGFGVGYKCACPIGQKLVNG 2124
C +C+L GY CACP G V G
Sbjct: 4338 QV-CSHLCLLRPG------GYSCACPQGSDFVTG 4364
Score = 147 bits (370), Expect = 1e-32
Identities = 140/557 (25%), Positives = 231/557 (41%), Gaps = 61/557 (10%)
Frame = +1
Query: 394 PASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCAD 573
P S+ +C S N F C +G C S +CDG DC D +DE R+ C F C
Sbjct: 22 PVSSQECGSGN-FRCDNG-YCIPASWRCDGTRDCLDDTDEIGCPPRS---CESGLFLCPA 76
Query: 574 KTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDN 753
+ CI SWVCD KDC+DG+DE C C+A + C N +C P ++RCD+ DC D
Sbjct: 77 EGTCIPSSWVCDEDKDCSDGADEQQNCAGTTCSAQQMTCSNGQCIPSEYRCDHVSDCPDG 136
Query: 754 SDE-----DECGEYRCPPG--------------------KWNCP----------GTGHCI 828
SDE C + C G + NC G+G CI
Sbjct: 137 SDERNCHYPTCDQLTCANGACYNTSQRCDQKVDCRDSSDEANCTTLCSQKEFECGSGECI 196
Query: 829 DQLKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTC 1008
+ +CD DC D +DE+ C+ + C G + TC +G ++ + C
Sbjct: 197 LRAYVCDHDNDCEDNSDERNCNYDTC-------------GGHQFTCSNGQCINQNW--VC 241
Query: 1009 SDINECAEFG---YCDQLCANHR---PGFTCSCLGDCFTL--------QMEHGPGKDNLT 1146
++C + G C+ ++HR + C G C ++ G ++N+T
Sbjct: 242 DGDDDCQDSGDEDGCESNQSHHRCYPREWACPGSGRCISIDKVCDGVPDCPEGDDENNVT 301
Query: 1147 MRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTD 1326
C + + + P + + S + IDFD D +I+
Sbjct: 302 SGRTCGMGVCSVLNCEYQCHQTPFGGECFCPPGHI--INSNDSRTCIDFD--DCQIWGI- 356
Query: 1327 RLAHSAFSADVDDEGEISQIKKLSLKSLVYPR---CLAVDWITNTLYIIESGSRRIDVSS 1497
D E + + L + + R C + D + I +G R + V
Sbjct: 357 --------CDQKCENRQGRHQCLCEEGYILERGQHCKSSDSFSAASVIFSNG-RDLLVGD 407
Query: 1498 YDGERRTVLLAD---GLTLPLDIALDPLRGEMFFTN--QLKLEAAAMDGTNRRTLVNTHT 1662
G +L G+ + +D R +F+T+ Q K+ + ++G N + ++N
Sbjct: 408 LHGRNFRILAESKNRGMVMGVDFHYQKHR--VFWTDPMQEKVFSTDINGLNTQEILNVSV 465
Query: 1663 HQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDR-RIVAQGMNVVPHPFGLALFDQ--Y 1833
+ VD ++Y V+ KV+R++ ++ +GN R ++ + + HP G+AL Y
Sbjct: 466 DTPENLAVDWINNKLYLVETKVNRIDVVNLEGNQRVTLITENLG---HPRGIALDPTVGY 522
Query: 1834 LYWTDWTRL-GVIQVEK 1881
L+++DW L G +VE+
Sbjct: 523 LFFSDWGSLSGQPKVER 539
Score = 122 bits (306), Expect = 3e-25
Identities = 95/355 (26%), Positives = 133/355 (36%), Gaps = 4/355 (1%)
Frame = +1
Query: 10735 QPAYPNPCGDNNGGCSH-LCLIGAGGNGYTCSCPDQFVLLSDQKTCEP-NCTERQFACGG 10908
+P CG N C + C+ + T C D +D+ C P +C F C
Sbjct: 21 EPVSSQECGSGNFRCDNGYCIPASWRCDGTRDCLDD----TDEIGCPPRSCESGLFLCPA 76
Query: 10909 DDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXX 11088
+ CIP W CD + DC DG+DE + C C + C+N C
Sbjct: 77 EGT-CIPSSWVCDEDKDCSDGADE--QQNCAGTTCSAQQMTCSNGQCIPSEYRCDHVSDC 133
Query: 11089 XXXXXEQNCD-KACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEADTLCMSAERNCTA 11265
E+NC CD C A G C SDEA+ + C+
Sbjct: 134 PDGSDERNCHYPTCD--QLTC-ANGACYNTSQRCDQKVDCRDSSDEANCTTL-----CSQ 185
Query: 11266 EEFRCNNNKCIAKAWRXXXXXXXXXXXXETPECAQIECKKGWTRCSSSYRCIPNWAFCNG 11445
+EF C + +CI +A+ C+
Sbjct: 186 KEFECGSGECILRAY-----------------------------------------VCDH 204
Query: 11446 QDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTT 11625
+DC DNSDE TC +F C ++G+CI + W+CD ++DC D+ DE +
Sbjct: 205 DNDCEDNSDERNCNYDTCGG-HQFTC-SNGQCINQNWVCDGDDDCQDSGDEDGCESNQSH 262
Query: 11626 RPCSESEFRC-NDGKCIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQCDDGTC 11787
C E+ C G+CI KVCDG C +G DE+ T R C G C
Sbjct: 263 HRCYPREWACPGSGRCISIDKVCDGVPDCPEGDDENNVT------SGRTCGMGVC 311
Score = 72.8 bits (177), Expect = 2e-10
Identities = 62/248 (25%), Positives = 97/248 (39%), Gaps = 35/248 (14%)
Frame = +1
Query: 11854 EDVSRRTCSPFEFECANSVCIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHS 12033
E VS + C F C N CIP + +DE C C+ L F C
Sbjct: 21 EPVSSQECGSGNFRCDNGYCIPASWRCDGTRDCLDDTDEIG--CPPRSCESGL-FLCPAE 77
Query: 12034 RLCLNILQLCNGFNDCG---------------------------PNDFSDEHLSMCSSFS 12132
C+ +C+ DC P+++ +H+S C S
Sbjct: 78 GTCIPSSWVCDEDKDCSDGADEQQNCAGTTCSAQQMTCSNGQCIPSEYRCDHVSDCPDGS 137
Query: 12133 EYGDC---SSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGC 12303
+ +C + DQ CANG C N + CD+K DC D+SDE C+ + E +G C
Sbjct: 138 DERNCHYPTCDQLTCANGACYNTSQRCDQKVDCRDSSDEANCTTLCSQKEFEC--GSGEC 195
Query: 12304 ---KHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNN-TCTQ-LCLNTKGSYLCR 12468
++C D C D S + + D C G+ TC+ C+N +++C
Sbjct: 196 ILRAYVCDHDND-----CED------NSDERNCNYDTCGGHQFTCSNGQCINQ--NWVCD 242
Query: 12469 CHEDYENN 12492
+D +++
Sbjct: 243 GDDDCQDS 250
Score = 67.4 bits (163), Expect = 1e-08
Identities = 55/222 (24%), Positives = 84/222 (37%), Gaps = 15/222 (6%)
Frame = +1
Query: 139 NTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHS 318
N C+ +F C +G+C+R + +P C ++Q+ C +
Sbjct: 2989 NCTMRTCSAGEFSCANGRCVRQSFRCDRRNDCGDYSDERGCSYPPCHANQFTC-----QN 3043
Query: 319 VSCIAEYQRCDNITDCADGSDEKD--CPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYD 492
CI + CD DC DGSDE++ C C F C +G C ++ + C+ D
Sbjct: 3044 GRCIPRFFVCDEDNDCGDGSDEQEHLCHTPEPTCPLHQ-FRCDNG-HCIEMGRVCNHVDD 3101
Query: 493 CRDLSDEKDSCSRNH---TACFQYQFRCADK-----TQCIQKSWVCDGSKDCAD---GSD 639
C D SDEK C N ++ + C D C+ + + C D +
Sbjct: 3102 CSDNSDEK-GCGINECLDSSISRCDHNCTDTITSFYCSCLPGYKLMSDKRSCVDIDECKE 3160
Query: 640 EPDTCEFKKC--TANEFQCKNKRCQPRKFRCDYYDDCGDNSD 759
P C +KC + CK C P R C NS+
Sbjct: 3161 SPQLCS-QKCENVVGSYICK---CAPGYIREPDGKSCRQNSN 3198
>gi|6806919|ref|NP_004516.1| low density lipoprotein-related protein 2;
megalin; calcium sensor protein; Heymann nephritis antigen
homolog [Homo sapiens]
gi|6166537|sp|P98164|LRP2_HUMAN Low-density lipoprotein
receptor-related protein 2 precursor (Megalin)
(Glycoprotein 330) (gp330)
gi|1809240|gb|AAB41649.1| gp330 precursor [Homo sapiens]
Length = 4655
Score = 2533 bits (6566), Expect = 0.0
Identities = 1522/4609 (33%), Positives = 2304/4609 (49%), Gaps = 100/4609 (2%)
Frame = +1
Query: 136 VNTASSVCNENDFRC-NDGKCIRTEWXXXXXXXXXXXXXXXXX-PHPGCKSDQWQCDTYT 309
+ A C + F+C ++G+CI + W C S Q C
Sbjct: 60 IGCAVVTCQQGYFKCQSEGQCIPSSWVCDQDQDCDDGSDERQDCSQSTCSSHQITCS--- 116
Query: 310 WHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKY 489
+ CI RCD++ DC DG+DE DC T + + D C++ S+KCD K
Sbjct: 117 --NGQCIPSEYRCDHVRDCPDGADENDCQYPTCEQ------LTCDNGACYNTSQKCDWKV 168
Query: 490 DCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKC 669
DCRD SDE + C+ C +F C + +CI +++VCD DC DGSDE C + C
Sbjct: 169 DCRDSSDEIN-CTE---ICLHNEFSCGNG-ECIPRAYVCDHDNDCQDGSDE-HACNYPTC 222
Query: 670 TANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGE-----YRCPPGKWNCPGTGHCIDQ 834
+F C + RC + + CD DDC DN DED C ++C P +W+CP +G CI
Sbjct: 223 GGYQFTCPSGRCIYQNWVCDGEDDCKDNGDEDGCESGPHDVHKCSPREWSCPESGRCISI 282
Query: 835 LKLCDGSKDCADGADEQQ------CSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRF 996
K+CDG DC DE CS LC +L CQ CH +P+GG C CP GY ++
Sbjct: 283 YKVCDGILDCPGREDENNTSTGKYCSMTLCSALNCQYQCHETPYGGACFCPPGYIINHND 342
Query: 997 HRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNA 1176
RTC + ++C +G CDQ C + C C + ++ D+ SN
Sbjct: 343 SRTCVEFDDCQIWGICDQKCESRPGRHLCHCEEGYILERGQYCKANDSFGEASIIFSNGR 402
Query: 1177 DKMKLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSAD 1356
D + + R + +N V G+ F Y +++FWTD + + FS D
Sbjct: 403 DLLIGDIHGRSFRILVESQNRGVAV----------GVAFHYHLQRVFWTDTVQNKVFSVD 452
Query: 1357 VDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADG 1536
++ I ++ +S+++ P LAVDW+ N +Y++E+ RID+ + DG R L+ +
Sbjct: 453 INGLN-IQEVLNVSVET---PENLAVDWVNNKIYLVETKVNRIDMVNLDGSYRVTLITEN 508
Query: 1537 LTLPLDIALDPLRGEMFFTN------QLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITA 1698
L P IA+DP G +FF++ + KLE A MDG+NR+ LV T +G+ +D+ +
Sbjct: 509 LGHPRGIAVDPTVGYLFFSDWESLSGEPKLERAFMDGSNRKDLVKTKLGWPAGVTLDMIS 568
Query: 1699 KRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVE 1878
KRVYWVD + D +E++ Y G R+ V G +++PHPFG++LF+ +++TDWT++ V++
Sbjct: 569 KRVYWVDSRFDYIETVTYDGIQRKTVVHGGSLIPHPFGVSLFEGQVFFTDWTKMAVLKAN 628
Query: 1879 KFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPC--TNADCEGMCIL 2052
KF ++ ++ P G++ YH + QP NPC N CE +C+L
Sbjct: 629 KFTETNPQVYYQA--SLRPYGVTVYHSLRQP----------YATNPCKDNNGGCEQVCVL 676
Query: 2053 SKDNGGFGVGYKCACPIGQKLVNGKR-CIDSIDYLLFSSNKIVRGIFPEINEKALAEAVL 2229
S G+G++C C G +L +R CI ++L+FSS +RGI ++ + + ++
Sbjct: 677 SHRTDNDGLGFRCKCTFGFQLDTDERHCIAVQNFLIFSSQVAIRGIPFTLSTQE--DVMV 734
Query: 2230 PISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMS 2409
P+S +G+ F D ++ F++D+ + I++ + DG G + + + S++
Sbjct: 735 PVSGNPSFFVGIDF----DAQDSTIFFSDMSKHMIFKQKIDGTGREILAANRVENVESLA 790
Query: 2410 FDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKGLLFY 2589
FDWISK LY+ D+ S+ V+++ + RR ++ L +P SVVVHP+ G LF+
Sbjct: 791 FDWISKNLYWTDSHYKSISVMRLADK--------TRRTVVQYLNNPRSVVVHPFAGYLFF 842
Query: 2590 AEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGK 2769
+ RPA I R DG + + NTTLG P+ +AID+A +RL W D I FDG
Sbjct: 843 TDWFRPAKIMRAWSDGSHLLPVINTTLGWPNGLAIDWAASRLYWVDAYFDKIEHSTFDGL 902
Query: 2770 NVVKLDIDNPI--PVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFS 2943
+ +L + P + I E++++ R +I RV K +GG ++R A I
Sbjct: 903 DRRRLGHIEQMTHPFGLAIFGEHLFFTDWRLGAIIRVRKADGGEMTVIRSGIA---YILH 959
Query: 2944 LKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINKENNHS 3123
LK+ Q + + C+ CF P+ + C C G + N+ +
Sbjct: 960 LKSYDVNIQTGSNACNQPTHPNGDCSHFCFPVPN------FQRVCGCPYGMRL-ASNHLT 1012
Query: 3124 CQKDPA-EKIEQLCSSNSTQFQCKNGRCIPKEWKCDGENDCLDESDEIDEKGDKCFH-ET 3297
C+ DP E + C S F CKNGRC+P + CDG +DC D SDE C
Sbjct: 1013 CEGDPTNEPPTEQCGLFS--FPCKNGRCVPNYYLCDGVDDCHDNSDE-----QLCGTLNN 1065
Query: 3298 ECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNHRCI 3477
C+ + C + + CIPA C C ++ CDNH+CI
Sbjct: 1066 TCSSSAFTCGHGE-CIPAHWRCDKRNDCVDGSDEH--NCPTHAPASCLDTQYTCDNHQCI 1122
Query: 3478 PEQWKXXXXXXXXXXXXEKLEMCGNA-TCAANQFSCANGRCIPIYWLCDGDNDCYDGTDE 3654
+ W EK C + TC +QF+C N RCI + ++CDGD DC DG+DE
Sbjct: 1123 SKNWVCDTDNDCGDGSDEK--NCNSTETCQPSQFNCPNHRCIDLSFVCDGDKDCVDGSDE 1180
Query: 3655 DKERCPPVQCSALQFRCANGRQCVPLRNHXXXXXXXXXXXXXXXXAVTAES-CTPDQFKC 3831
C + C+A QF+CA+G +C+ + N C D+F+C
Sbjct: 1181 --VGCV-LNCTASQFKCASGDKCIGVTNRCDGVFDCSDNSDEAGCPTRPPGMCHSDEFQC 1237
Query: 3832 VSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKCGNGRCILNNWLCDGEND 4011
G+CIP W+ SDE C + C S F C NG CI WLCD +ND
Sbjct: 1238 QEDGICIPNFWECDGHPDCLYGSDEHN-ACVP-KTCPSSYFHCDNGNCIHRAWLCDRDND 1295
Query: 4012 CGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGGRCA 4191
CGD SDE + C T +CP C C+ L +CDG CP GTDE C
Sbjct: 1296 CGDMSDE---KDCPTQ--PFRCPSWQWQCLG-HNICVNLSVVCDGIFDCPNGTDESPLCN 1349
Query: 4192 RDLCSADRAGCSFKCHNSPNGPICSCPFGEQLVNKTK-CEPENECLDSSSCSQRCKDEKH 4368
+ CS GC+ +C P G C CP G L N +K CE +EC SCSQ C + +
Sbjct: 1350 GNSCSDFNGGCTHECVQEPFGAKCLCPLGFLLANDSKTCEDIDECDILGSCSQHCYNMRG 1409
Query: 4369 GFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGAIVENA-- 4542
F CSCD GY L+ D RTCKV + + + V+++N+I +D H ++VEN
Sbjct: 1410 SFRCSCDTGYMLESDGRTCKVTAS-ESLLLLVASQNKII-ADSVTSQVHNIYSLVENGSY 1467
Query: 4543 -IALAWDSLTDRIYWSDIREKKILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVD 4719
+A+ +DS++ RI+WSD + K SA +NGT+ V + +TE IA+DWVGRNLYW D
Sbjct: 1468 IVAVDFDSISGRIFWSDATQGKTWSAFQNGTDRRVVFDSSIILTETIAIDWVGRNLYWTD 1527
Query: 4720 SSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKG--VMFWTDWGQNPCIERASMDG 4893
+L TIEV+ + D RT+L+ +N++ PRG+A+DPR ++FW+DWG +P IERASMDG
Sbjct: 1528 YALETIEVSKI-DGSHRTVLISKNLTNPRGLALDPRMNEHLLFWSDWGHHPRIERASMDG 1586
Query: 4894 TDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPH 5073
+ R +IV+ KI+WP + +DY +YF DS LD++DF +Y+G R QV+AS ++HP+
Sbjct: 1587 SMRTVIVQDKIFWPCGLTIDYPNRLLYFMDSYLDYMDFCDYNGHHRRQVIASDLIIRHPY 1646
Query: 5074 ALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPC 5253
AL +FED +Y++DR +++ K+ G S + LG+VAVHP QP NPC
Sbjct: 1647 ALTLFEDSVYWTDRATRRVMRANKWHGGNQSVV-MYNIQWPLGIVAVHPSKQPN-SVNPC 1704
Query: 5254 STNPCSHLCLLNNKNT--FTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNVFGIEMNSA 5427
+ + CSHLCLL+++ ++C CP G L C+ D +PFL+ +++ +FGI +N
Sbjct: 1705 AFSRCSHLCLLSSQGPHFYSCVCPSGWSLSPDLLNCLRDDQPFLITVRQHIIFGISLNPE 1764
Query: 5428 SEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNG 5607
+ MVP++G+ N D +D + ++ +E+ I+R +G
Sbjct: 1765 VKSND----AMVPIAGIQNGLDVEFDDAEQYIYWVENPGE------------IHRVKTDG 1808
Query: 5608 GNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGK-QYRSVILSNDQSXX 5784
N+T S ++ + L DW RNL N TQ+IE++ G +YR +++ND +
Sbjct: 1809 TNRTVFASISMVGPSMNLALDWISRNLYSTNPRTQSIEVLTLHGDIRYRKTLIANDGTAL 1868
Query: 5785 XXXXXXXXXXXXXKGYVFWLDRG-GGAADAKVARAGLDGSNPLVIASNDLAELDHIAIDT 5961
+G ++W D+G AK+A A +DG++ + + +L L+ + +D
Sbjct: 1869 GVGFPIGITVDPARGKLYWSDQGTDSGVPAKIASANMDGTSVKTLFTGNLEHLECVTLDI 1928
Query: 5962 TNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAFDSIE-VA 6138
++Y++ G I DG DR +L P G+A + L+Y D ++ IE V
Sbjct: 1929 EEQKLYWAVTGRGVIERGNVDGTDR-MILVHQLSHPWGIAVHDSFLYYTDEQYEVIERVD 1987
Query: 6139 TINGDSQPPQWTHFKKDVENLANIKALQPR-ASSSGHPCHINNGNCDHICIPLMFAQRTC 6315
G ++ + +V NL ++ R A+ S + C N C IC+P+ +C
Sbjct: 1988 KATGANK----IVLRDNVPNLRGLQVYHRRNAAESSNGCSNNMNACQQICLPVPGGLFSC 2043
Query: 6316 TCANGY-VKDGQTSCKLFDESFVIVATKTKVIGYPIDETQSKGVAMEPIGGLSITG--VD 6486
CA G+ + SC ++ SF++V+ + + G+ + E M P+ G VD
Sbjct: 2044 ACATGFKLNPDNRSCSPYN-SFIVVSMLSAIRGFSL-ELSDHSETMVPVAGQGRNALHVD 2101
Query: 6487 YDYESKTIYVAEASGI---NKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINYNMYF 6657
D S IY + S + I SS ++ IG ++ +A+DW+ N+YF
Sbjct: 2102 VDVSSGFIYWCDFSSSVASDNAIRRIKPDGSSLMNIVTHGIGENGVRGIAVDWVAGNLYF 2161
Query: 6658 INHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQRSFLD 6837
N T IEV +++ TYR++LL + P I VDP +RYL+WAD GQ+P I+RSFLD
Sbjct: 2162 TNAFVSETLIEVLRINTTYRRVLLKVTVDMPRHIVVDPKNRYLFWADYGQRPKIERSFLD 2221
Query: 6838 GSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPELVR--SDIASAA 7011
+ R V+VS GI P L VD + +YW D +D I R+R G E++R S +
Sbjct: 2222 CTNRTVLVSEGIVTPRGLAVDRSDGYVYWVDDSLDIIARIRINGENSEVIRYGSRYPTPY 2281
Query: 7012 GVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRAS 7191
G+ + ++ W D L+K+F+A+ +P T PT + ++ + DV +F QPR
Sbjct: 2282 GITVFENSIIWVDRNLKKIFQASKEPENTE---PPTVIRDNINWLRDVTIFDKQVQPR-- 2336
Query: 7192 SPCQITDNL---RKSPCTQLCFATPGTQTPTCSCARGVLK--GRTCE-EPDTYIMFSDGD 7353
SP ++ +N C+ LCFA PG TP C CA G L+ G+ C + +++F+ +
Sbjct: 2337 SPAEVNNNPCLENNGGCSHLCFALPGLHTPKCDCAFGTLQSDGKNCAISTENFLIFALSN 2396
Query: 7354 KIIDVAIEPDVKASRPLKDPFPEIS---NLQTFDVDVNLRRVYFVVESPVGVN-ISWFSM 7521
+ + ++P+ + PF I+ + + D D R+YF GV IS+ ++
Sbjct: 2397 SLRSLHLDPENHSP-----PFQTINVERTVMSLDYDSVSDRIYFTQNLASGVGQISYATL 2451
Query: 7522 NNAENPRLVFGASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTIA 7701
++ + V A I + DW+T++IY++ + ++ G + + IA
Sbjct: 2452 SSGIHTPTVI-------ASGIGTADGIAFDWITRRIYYSDYLNQMINSMAEDGSNRTVIA 2504
Query: 7702 SGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIA 7881
A+ +DPC G L+W+D + T +IER+ L G R IV+ S+ +P+ +
Sbjct: 2505 RVPKPRAIVLDPCQGYLYWAD--WDTHA-----KIERATLGGNFRVPIVNSSLVMPSGLT 2557
Query: 7882 VDFRNQKIYWADVNRLNIEVADYDGQNRKVIASG-YRAKSLDIWDRWLYMSDPLSNGVFR 8058
+D+ +YW D + IE + G +R+VI + A L ++ +++Y +D + ++R
Sbjct: 2558 LDYEEDLLYWVDASLQRIERSTLTGVDREVIVNAAVHAFGLTLYGQYIYWTDLYTQRIYR 2617
Query: 8059 IDKESGSG----LENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQL 8226
+K GSG N++S R + V+ + Q CN C+ NGGC +
Sbjct: 2618 ANKYDGSGQIAMTTNLLSQPR--------GINTVVKNQKQQCN----NPCEQFNGGCSHI 2665
Query: 8227 CTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSEPAKECLPPYNFQCGD 8406
C G ++ QC + L C++ A +F C +
Sbjct: 2666 CAP-----GPNGAECQCPHEGNWYLANNR-----KHCIVDNGERCGAS------SFTCSN 2709
Query: 8407 GSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHIDDCGDG 8586
G CI CD+ DC D SDE + C +C C N RC+ + +C++ +DCGDG
Sbjct: 2710 GRCISEEWKCDNDNDCGDGSDEMESVCALHTCSPTAFTCANGRCVQYSYRCDYYNDCGDG 2769
Query: 8587 SDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPGLPIDCRGV 8766
SDE C A F C+N CI + +C+G ++CHD SDE CP C+
Sbjct: 2770 SDEAGCLFRDCNATTEFMCNNRRCIPREFICNGVDNCHDNNTSDEK--NCPDRT--CQSG 2825
Query: 8767 KVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCIPETWQCDG 8946
+C N+NICI LCDG +DCGD +DEN +C C+ +C SGRCIP+ W CD
Sbjct: 2826 YTKCHNSNICIPRVYLCDGDNDCGDNSDENPTYCTTHTCSSSEFQCASGRCIPQHWYCDQ 2885
Query: 8947 DNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXXXXXXHSRH 9126
+ DC D DE +C + ++ C+ D F+CD +CI +I RH
Sbjct: 2886 ETDCFDASDEP-ASCGHS--ERTCLADE-FKCDGGRCIPSEWICDGDNDCGDMSDEDKRH 2941
Query: 9127 GCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECNK 9306
C N+ C+D EF C ++ P CIP++W+CDGDV C G DE+ + + C++
Sbjct: 2942 QCQNQNCSDSEFLCVNDRP---PDRRCIPQSWVCDGDVDCTDGYDENQNCTR---RTCSE 2995
Query: 9307 GEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCANHKCVPNSWKCDGN 9486
EF C CI + CD NDC D SDE C Y +CQ + F C N +C+ ++ CD +
Sbjct: 2996 NEFTCGYGLCIPKIFRCDRHNDCGDYSDERG-CLYQTCQQNQFTCQNGRCISKTFVCDED 3054
Query: 9487 DDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLC 9666
+DC DGSDE C +F+C +G CI+ K+C+ DC D SDE C
Sbjct: 3055 NDCGDGSDEL----MHLCHTPEPTCPPHEFKCDNGRCIEMMKLCNHLDDCLDNSDEKG-C 3109
Query: 9667 FIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNECYEGISGCSQKCD 9846
I+EC C+ C D + C C G+ + +SD+++C +++EC E CSQKC+
Sbjct: 3110 GINECHDPSISGCDHNCTDTLTSFYCSCRPGYKL-MSDKRTCVDIDECTEMPFVCSQKCE 3168
Query: 9847 DKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYELAAQGFD 10026
+ IGSY C C GY D +C++ EP+ + +N++Y+R ++IDG Y L +G D
Sbjct: 3169 NVIGSYICKCAPGYLREPDGKTCRQNS-NIEPYLIFSNRYYLRNLTIDGYFYSLILEGLD 3227
Query: 10027 NVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDWVGR 10206
NVV+LD D EK+ Y ID + + R+ L++ + ET++ H + E +AVDWV R
Sbjct: 3228 NVVALDFDRVEKRLYWIDTQRQVIERMFLNKTNK-----ETIINHRLPAAESLAVDWVSR 3282
Query: 10207 KLYMLNRQERSIRVCELDGRFCKTLIRDRIQ--------QPKAIVVHPGKGYLFFTEWSL 10362
KLY L+ + + V +L+G + L + + P+ + +HP GYL++ +W
Sbjct: 3283 KLYWLDARLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLYWADWGH 3342
Query: 10363 QPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGN 10542
+ YIGR+ +DG+ + + L WPN I IDY +D L+W DAHL I + D +G+
Sbjct: 3343 RAYIGRVGMDGTNKSV-----IISTKLEWPNGITIDYTNDLLYWADAHLGYIEYSDLEGH 3397
Query: 10543 GRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDLRIV 10722
R + H ++ +F+D +YW DWN R V + +K+ G N L T P D+ +
Sbjct: 3398 HRHTVYDGALPHPFAITIFEDTIYWTDWNTRTVEKGNKYDGSNRQTLVNTTHRPFDIHVY 3457
Query: 10723 HPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQF--VLLSDQKTCEPNCTERQF 10896
HP RQP NPCG NNGGCSHLCLI GG G+TC CPD F + LS C P C+ QF
Sbjct: 3458 HPYRQPIVSNPCGTNNGGCSHLCLIKPGGKGFTCECPDDFRTLQLSGSTYCMPMCSSTQF 3517
Query: 10897 ACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRPFQIXXX 11076
C ++ KCIP W CDG+ DC DGSDE ++C QR C +G+FQC++ NCT P +
Sbjct: 3518 LCANNE-KCIPIWWKCDGQKDCSDGSDE--LALCPQRFCRLGQFQCSDGNCTSPQTLCNA 3574
Query: 11077 XXXXXXXXXEQN--CDK-ACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEADTLCMSA 11247
E C+ CD ++C A RCIP + SDE + C A
Sbjct: 3575 HQNCPDGSDEDRLLCENHHCDSNEWQC-ANKRCIPESWQCDTFNDCEDNSDEDSSHC--A 3631
Query: 11248 ERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXE-TPEC-AQIECKKGWTR--CSSSYR 11415
R C +FRC N +CI +AW+ E EC + +T C ++YR
Sbjct: 3632 SRTCRPGQFRCANGRCIPQAWKCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFSCKTNYR 3691
Query: 11416 CIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSD 11595
CIP WA CNG DDCRDNSDE TC VG+FRC + CIP RW CD +NDCGDNSD
Sbjct: 3692 CIPKWAVCNGVDDCRDNSDEQGCEERTCHPVGDFRC-KNHHCIPLRWQCDGQNDCGDNSD 3750
Query: 11596 ELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQCD 11775
E + + R C+ESEFRC + +CIP +CD C D DE C +R C P + QC
Sbjct: 3751 EENCA----PRECTESEFRCVNQQCIPSRWICDHYNDCGDNSDERDCEMRTCHPEYFQCT 3806
Query: 11776 DGTCIAEHKWCDRKKDCPNAADELHCED--VSRRTCSPFEFECANSVCIPRKFMXXXXXX 11949
G C+ CD DC +A+DE C C FEC N VCIP +
Sbjct: 3807 SGHCVHSELKCDGSADCLDASDEADCPTRFPDGAYCQATMFECKNHVCIPPYWKCDGDDD 3866
Query: 11950 XXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSF 12129
SDE C C+ P RFRC ++R C+ ++CNG +DCG D +DE C
Sbjct: 3867 CGDGSDEELHLCLDVPCNSPNRFRCDNNR-CIYSHEVCNGVDDCG--DGTDETEEHCRKP 3923
Query: 12130 SEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKH 12309
+ C+ ++KC NG C+ CD DDCGD SDE+GC+K +T E C+
Sbjct: 3924 TP-KPCTEYEYKCGNGHCIPHDNVCDDADDCGDWSDELGCNKGKERTCAENI-----CEQ 3977
Query: 12310 ICTDVRD-GFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGSYLCRCHEDYE 12486
CT + + GF C C GF + C+DI+EC TC Q C NTKGSY C C + +
Sbjct: 3978 NCTQLNEGGFICSCTAGFETNVFDRTSCLDINECEQFGTCPQHCRNTKGSYECVCADGFT 4037
Query: 12487 NNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXXX 12666
+ + GK C A+G + +++ + + + +L + +
Sbjct: 4038 S---MSDRPGKRCAAEGSSPLLLLPDNVRIRKYNLSSERFSEYLQDEEYIQAVDYDWDPK 4094
Query: 12667 XPRKELMYWI---DGSE-RTIYRSAIANGNQSHEGQKLDVDFAAMGVV-PTAIAVDYTTG 12831
++Y+ +GS I R+ I N +VD V+ P IAVD+
Sbjct: 4095 DIGLSVVYYTVRGEGSRFGAIKRAYIPNFESGRNNLVQEVDLKLKYVMQPDGIAVDWVGR 4154
Query: 12832 NLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALI 13011
+++ + V + KR I V DGRY K +++ L QP A+
Sbjct: 4155 HIYWSDV-----------KNKR------------IEVAKLDGRYRKWLISTDLDQPAAIA 4191
Query: 13012 TAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKY 13191
P G + ++D G KIE A M+G R I+V + + PT ++ID +RIYW D K
Sbjct: 4192 VNPKLGLMFWTDWGKEPKIESAWMNGEDRNILVFEDLGWPTGLSIDYLNNDRIYWSDFKE 4251
Query: 13192 RRVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSRESKTLYVQDKFGRGR------V 13353
++ + DG++R + + PY++D+FE+ +YW+S+E ++ Q+KFG+G+ V
Sbjct: 4252 DVIETIKYDGTDRRVIAKEAMNPYSLDIFEDQLYWISKEKGEVWKQNKFGQGKKEKTLVV 4311
Query: 13354 SVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTGFACLCPDG--IVPQ 13527
+ + + H +R + ++V + CSHLC+ P G++C CP G +
Sbjct: 4312 NPWLTQVRIFHQLRYN--------KSVPNLCKQICSHLCLLRPG-GYSCACPQGSSFIEG 4362
Query: 13528 LDGSCATQHVEALTMPKQCKCTNGGKCRLDGS----CECTSDFEGDQCE 13662
C + +P C+C +GG C D + C+C S + G CE
Sbjct: 4363 STTECDAAIELPINLPPPCRCMHGGNCYFDETDLPKCKCPSGYTGKYCE 4411
Score = 399 bits (1024), Expect = e-108
Identities = 301/1086 (27%), Positives = 485/1086 (43%), Gaps = 32/1086 (2%)
Frame = +1
Query: 3169 NSTQFQCKNGRCIPKEWKCDGENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKKCIP 3348
+S F+C +G CIP +W+CDG DC D++DEI C T C + KC++ +CIP
Sbjct: 29 DSAHFRCGSGHCIPADWRCDGTKDCSDDADEIG-----CAVVT-CQQGYFKCQSEGQCIP 82
Query: 3349 AQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXX 3528
+ +D + C++ + C N +CIP +++
Sbjct: 83 SSWVCDQDQDCDDGSDER----QDCSQSTCSSHQITCSNGQCIPSEYRCDHVRDCPDGAD 138
Query: 3529 EKLEMCGNATCAANQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCA 3708
E C TC Q +C NG C CD DC D +DE C + C +F C
Sbjct: 139 E--NDCQYPTC--EQLTCDNGACYNTSQKCDWKVDCRDSSDE--INCTEI-CLHNEFSCG 191
Query: 3709 NGRQCVPLRNHXXXXXXXXXXXXXXXXAVTAESCTPDQFKCVSSGLCIPASWKXXXXXXX 3888
NG +C+P A +C QF C SG CI +W
Sbjct: 192 NG-ECIP--RAYVCDHDNDCQDGSDEHACNYPTCGGYQFTC-PSGRCIYQNWVCDGEDDC 247
Query: 3889 XXXSDEPKFGCTSG----RQCSSDQFKC-GNGRCILNNWLCDGENDCGDGSDESSERGCK 4053
DE GC SG +CS ++ C +GRCI +CDG DC DE++
Sbjct: 248 KDNGDED--GCESGPHDVHKCSPREWSCPESGRCISIYKVCDGILDCPGREDENN----- 300
Query: 4054 TSMNARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCSFK 4233
T G C+ LCSA C ++
Sbjct: 301 --------------------------------------TSTGKYCSMTLCSA--LNCQYQ 320
Query: 4234 CHNSPNGPICSCPFGEQLVN---KTKCEPENECLDSSSCSQRCKDEKHGFTCSCDEGYEL 4404
CH +P G C CP G ++N C ++C C Q+C+ C C+EGY L
Sbjct: 321 CHETPYGGACFCPPG-YIINHNDSRTCVEFDDCQIWGICDQKCESRPGRHLCHCEEGYIL 379
Query: 4405 DVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGAIVEN-----AIALAWDSLT 4569
+ + CK D+ + I SN + D + +F +VE+ A+ +A+
Sbjct: 380 E-RGQYCKANDSFGEASIIFSNGRDLLIGD---IHGRSFRILVESQNRGVAVGVAFHYHL 435
Query: 4570 DRIYWSDIREKKILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVDSSLNTIEVAN 4749
R++W+D + K+ S + NG N + ++ E +A+DWV +Y V++ +N I++ N
Sbjct: 436 QRVFWTDTVQNKVFSVDINGLNIQEVLNVSVETPENLAVDWVNNKIYLVETKVNRIDMVN 495
Query: 4750 LEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDW---GQNPCIERASMDGTDRQIIVKT 4920
L D R L+ +N+ PRGIAVDP G +F++DW P +ERA MDG++R+ +VKT
Sbjct: 496 L-DGSYRVTLITENLGHPRGIAVDPTVGYLFFSDWESLSGEPKLERAFMDGSNRKDLVKT 554
Query: 4921 KIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFEDMM 5100
K+ WP + LD + RVY+ DS+ D+I+ V YDG R V+ + HP +++FE +
Sbjct: 555 KLGWPAGVTLDMISKRVYWVDSRFDYIETVTYDGIQRKTVVHGGSLIPHPFGVSLFEGQV 614
Query: 5101 YYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTN--PCSH 5274
+++D + K+ Y + + GV H + QP NPC N C
Sbjct: 615 FFTDWTKMAVLKANKFTETNPQVYYQASL-RPYGVTVYHSLRQP-YATNPCKDNNGGCEQ 672
Query: 5275 LCLLNNKNT-----FTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNVFGIEMNSASEKE 5439
+C+L+++ F CKC G +LD + CI + FL+ + + GI +++++
Sbjct: 673 VCVLSHRTDNDGLGFRCKCTFGFQLDTDERHCI-AVQNFLIFSSQVAIRGIPFTLSTQED 731
Query: 5440 TPVLAGMVPLSGLGNAF-DAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNGGNK 5616
MVP+SG + F +DA +F + + H I++ ++G +
Sbjct: 732 V-----MVPVSGNPSFFVGIDFDAQDSTIFFSDMSKH-----------MIFKQKIDGTGR 775
Query: 5617 TKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVI--LSNDQSXXXX 5790
+ ++ V ++ L FDW +NL + ++I ++R K R+V+ L+N +S
Sbjct: 776 EILAANRV-ENVESLAFDWISKNLYWTDSHYKSISVMRLADKTRRTVVQYLNNPRSVVVH 834
Query: 5791 XXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAIDTTNT 5970
GY+F+ D AK+ RA DGS+ L + + L + +AID +
Sbjct: 835 PFA---------GYLFFTD---WFRPAKIMRAWSDGSHLLPVINTTLGWPNGLAIDWAAS 882
Query: 5971 RVYFSEAKAGRISSVTYDGQDRHYV-LSDGGRQPNGLAFYGDRLFYADSAFDS-IEVATI 6144
R+Y+ +A +I T+DG DR + + P GLA +G+ LF+ D + I V
Sbjct: 883 RLYWVDAYFDKIEHSTFDGLDRRRLGHIEQMTHPFGLAIFGEHLFFTDWRLGAIIRVRKA 942
Query: 6145 NGDSQPPQWTHFKKDVENLANIKA----LQPRASSSGHPCHINNGNCDHICIPLMFAQRT 6312
+G + T + + + ++K+ +Q +++ P H NG+C H C P+ QR
Sbjct: 943 DGG----EMTVIRSGIAYILHLKSYDVNIQTGSNACNQPTH-PNGDCSHFCFPVPNFQRV 997
Query: 6313 CTCANG 6330
C C G
Sbjct: 998 CGCPYG 1003
Score = 336 bits (862), Expect = 9e-90
Identities = 210/713 (29%), Positives = 326/713 (45%), Gaps = 48/713 (6%)
Frame = +1
Query: 8875 QQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNL- 9051
Q+C + RC SG CIP W+CDG DCSD DE C C Y F+C +
Sbjct: 26 QECDSAHFRCGSGHCIPADWRCDGTKDCSDDADE--IGCAVVT----CQQGY-FKCQSEG 78
Query: 9052 KCISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCD 9231
+CI +++ R C TC+ + C++ +CIP + CD
Sbjct: 79 QCIPSSWV--CDQDQDCDDGSDERQDCSQSTCSSHQITCSNG--------QCIPSEYRCD 128
Query: 9232 GDVTCAGGEDES-------------TELCKTEKKECN-------------------KGEF 9315
C G DE+ C ++C+ EF
Sbjct: 129 HVRDCPDGADENDCQYPTCEQLTCDNGACYNTSQKCDWKVDCRDSSDEINCTEICLHNEF 188
Query: 9316 RCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCANHKCVPNSWKCDGNDDC 9495
C N CI + CD DNDC DGSDEHA C Y +C F C + +C+ +W CDG DDC
Sbjct: 189 SCGNGECIPRAYVCDHDNDCQDGSDEHA-CNYPTCGGYQFTCPSGRCIYQNWVCDGEDDC 247
Query: 9496 EDGSDEKDCPKNSASAQKASKCSNGQFQC-TSGECIDDAKVCDRNFDCTDRSDESSLCFI 9672
+D DE C + KCS ++ C SG CI KVCD DC R DE++
Sbjct: 248 KDNGDEDGC---ESGPHDVHKCSPREWSCPESGRCISIYKVCDGILDCPGREDENNTSTG 304
Query: 9673 DECS--LAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNEC-YEGISGCSQKC 9843
CS L C+ +C + G C C G+ I+ +D ++C ++C GI C QKC
Sbjct: 305 KYCSMTLCSALNCQYQCHETPYGGACFCPPGYIINHNDSRTCVEFDDCQIWGI--CDQKC 362
Query: 9844 DDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYELAAQGF 10023
+ + G + C C +GY L + CK + E + +N + I G + + +
Sbjct: 363 ESRPGRHLCHCEEGYILERGQY-CKANDSFGEASIIFSNGRDLLIGDIHGRSFRILVESQ 421
Query: 10024 DNVVSLDIDLTE--KKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDW 10197
+ V++ + ++ + D + ++ VD++ + + + VL +V E +AVDW
Sbjct: 422 NRGVAVGVAFHYHLQRVFWTDTVQNKVFSVDINGL-----NIQEVLNVSVETPENLAVDW 476
Query: 10198 VGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFFTEW---SLQP 10368
V K+Y++ + I + LDG + TLI + + P+ I V P GYLFF++W S +P
Sbjct: 477 VNNKIYLVETKVNRIDMVNLDGSYRVTLITENLGHPRGIAVDPTVGYLFFSDWESLSGEP 536
Query: 10369 YIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGR 10548
+ R +DGS L + LGWP + +D S R++W D+ + I + +DG R
Sbjct: 537 KLERAFMDGSNRKD-----LVKTKLGWPAGVTLDMISKRVYWVDSRFDYIETVTYDGIQR 591
Query: 10549 RHI--PAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDLRIV 10722
+ + H + +F+ +++ DW VL+ +K+T N + + P + +
Sbjct: 592 KTVVHGGSLIPHPFGVSLFEGQVFFTDWTKMAVLKANKFTETNPQVYYQASLRPYGVTVY 651
Query: 10723 HPMRQPAYPNPCGDNNGGCSHLCLIG----AGGNGYTCSCPDQFVLLSDQKTC 10869
H +RQP NPC DNNGGC +C++ G G+ C C F L +D++ C
Sbjct: 652 HSLRQPYATNPCKDNNGGCEQVCVLSHRTDNDGLGFRCKCTFGFQLDTDERHC 704
Score = 240 bits (613), Expect = 6e-61
Identities = 217/773 (28%), Positives = 313/773 (40%), Gaps = 109/773 (14%)
Frame = +1
Query: 133 SVNTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTW 312
S + AS C FRC +G+CI W P C S CD +T
Sbjct: 3627 SSHCASRTCRPGQFRCANGRCIPQAW---KCDVDNDCGDHSDEPIEECMSSAHLCDNFTE 3683
Query: 313 HSVS----CIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCD 480
S CI ++ C+ + DC D SDE+ C T C F C + C + +CD
Sbjct: 3684 FSCKTNYRCIPKWAVCNGVDDCRDNSDEQGCEERT--CHPVGDFRCKN-HHCIPLRWQCD 3740
Query: 481 GKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEF 660
G+ DC D SDE++ R C + +FRC ++ QCI W+CD DC D SDE D CE
Sbjct: 3741 GQNDCGDNSDEENCAPRE---CTESEFRCVNQ-QCIPSRWICDHYNDCGDNSDERD-CEM 3795
Query: 661 KKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGT-----GH- 822
+ C FQC + C + +CD DC D SDE +C R P G + C T H
Sbjct: 3796 RTCHPEYFQCTSGHCVHSELKCDGSADCLDASDEADC-PTRFPDGAY-CQATMFECKNHV 3853
Query: 823 CIDQLKLCDGSKDCADGADEQ---------------QCSQNLCPSL--------GCQAGC 933
CI CDG DC DG+DE+ +C N C C G
Sbjct: 3854 CIPPYWKCDGDDDCGDGSDEELHLCLDVPCNSPNRFRCDNNRCIYSHEVCNGVDDCGDGT 3913
Query: 934 HPS------PHGGECT-----CPSGYKLDDRFHRTCSDINECAEF--------------- 1035
+ P CT C +G+ + C D ++C ++
Sbjct: 3914 DETEEHCRKPTPKPCTEYEYKCGNGHCIP--HDNVCDDADDCGDWSDELGCNKGKERTCA 3971
Query: 1036 -GYCDQLCAN-HRPGFTCSCLG----------DCFTL----QMEHGPGKDNLTMRGY-CV 1164
C+Q C + GF CSC C + Q P T Y CV
Sbjct: 3972 ENICEQNCTQLNEGGFICSCTAGFETNVFDRTSCLDINECEQFGTCPQHCRNTKGSYECV 4031
Query: 1165 -----SNNADKM-KLFVARREGLYRLNPKNPDEEVKKLASGEF---------IYGIDFDY 1299
++ +D+ K A L P N L+S F I +D+D+
Sbjct: 4032 CADGFTSMSDRPGKRCAAEGSSPLLLLPDNVRIRKYNLSSERFSEYLQDEEYIQAVDYDW 4091
Query: 1300 GDRKI-----FWTDRLAHSAFSA--------DVDDEGEISQIKKLSLKSLVYPRCLAVDW 1440
+ I ++T R S F A + Q L LK ++ P +AVDW
Sbjct: 4092 DPKDIGLSVVYYTVRGEGSRFGAIKRAYIPNFESGRNNLVQEVDLKLKYVMQPDGIAVDW 4151
Query: 1441 ITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTN---QLKLE 1611
+ +Y + ++RI+V+ DG R L++ L P IA++P G MF+T+ + K+E
Sbjct: 4152 VGRHIYWSDVKNKRIEVAKLDGRYRKWLISTDLDQPAAIAVNPKLGLMFWTDWGKEPKIE 4211
Query: 1612 AAAMDGTNRRTLVNTHTHQVSGIVVD-ITAKRVYWVDPKVDRLESIDYQGNDRRIVA-QG 1785
+A M+G +R LV +G+ +D + R+YW D K D +E+I Y G DRR++A +
Sbjct: 4212 SAWMNGEDRNILVFEDLGWPTGLSIDYLNNDRIYWSDFKEDVIETIKYDGTDRRVIAKEA 4271
Query: 1786 MNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMA 1965
MN P+ L +F+ LYW + V + KFG K N + + +H +
Sbjct: 4272 MN----PYSLDIFEDQLYWISKEKGEVWKQNKFGQGKK--EKTLVVNPWLTQVRIFHQLR 4325
Query: 1966 QPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNG 2124
+ N C C +C+L GY CACP G + G
Sbjct: 4326 ---------YNKSVPNLCKQI-CSHLCLLRPG------GYSCACPQGSSFIEG 4362
Score = 239 bits (609), Expect = 2e-60
Identities = 187/684 (27%), Positives = 283/684 (41%), Gaps = 27/684 (3%)
Frame = +1
Query: 130 ASVNTASSVCNENDFRCNDGKCIRTEW---XXXXXXXXXXXXXXXXXPHPGCKSDQWQCD 300
AS + C ++F+C+ G+CI +EW + C ++ C
Sbjct: 2897 ASCGHSERTCLADEFKCDGGRCIPSEWICDGDNDCGDMSDEDKRHQCQNQNCSDSEFLCV 2956
Query: 301 TYTWHSVSCIAEYQRCDNITDCADGSDE-KDCPASTVDCSSQNVFMCADGRQCFDVSKKC 477
CI + CD DC DG DE ++C T S+N F C G C +C
Sbjct: 2957 NDRPPDRRCIPQSWVCDGDVDCTDGYDENQNCTRRT---CSENEFTCGYG-LCIPKIFRC 3012
Query: 478 DGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDE-PDTC 654
D DC D SDE+ + C Q QF C +CI K++VCD DC DGSDE C
Sbjct: 3013 DRHNDCGDYSDERGCL---YQTCQQNQFTC-QNGRCISKTFVCDEDNDCGDGSDELMHLC 3068
Query: 655 EFKK--CTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCI 828
+ C +EF+C N RC C++ DDC DNSDE C
Sbjct: 3069 HTPEPTCPPHEFKCDNGRCIEMMKLCNHLDDCLDNSDEKGC------------------- 3109
Query: 829 DQLKLCDGSKDCADGADEQQCSQNLCPSL-GCQAGCHPSPHGGECTCPSGYKL-DDRFHR 1002
G +C D PS+ GC C + C+C GYKL D+ R
Sbjct: 3110 -------GINECHD------------PSISGCDHNCTDTLTSFYCSCRPGYKLMSDK--R 3148
Query: 1003 TCSDINECAEFGY-CDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNAD 1179
TC DI+EC E + C Q C N + C C + + + + N + Y + +N
Sbjct: 3149 TCVDIDECTEMPFVCSQKCENVIGSYICKC-APGYLREPDGKTCRQNSNIEPYLIFSNRY 3207
Query: 1180 KMKLFVARREG-LYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTD---RLAHSAF 1347
++ +G Y L + D + +DFD +++++W D ++ F
Sbjct: 3208 YLRNLTI--DGYFYSLILEGLDN----------VVALDFDRVEKRLYWIDTQRQVIERMF 3255
Query: 1348 SADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLL 1527
+ E I+ L LAVDW++ LY +++ + VS +G R +L
Sbjct: 3256 LNKTNKETIINH-------RLPAAESLAVDWVSRKLYWLDARLDGLFVSDLNGGHRRMLA 3308
Query: 1528 ADGLTL--------PLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVS 1674
+ P +AL P G +++ ++ + MDGTN+ +++T +
Sbjct: 3309 QHCVDANNTFCFDNPRGLALHPQYGYLYWADWGHRAYIGRVGMDGTNKSVIISTKLEWPN 3368
Query: 1675 GIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWT 1854
GI +D T +YW D + +E D +G+ R V G +PHPF + +F+ +YWTDW
Sbjct: 3369 GITIDYTNDLLYWADAHLGYIEYSDLEGHHRHTVYDG--ALPHPFAITIFEDTIYWTDWN 3426
Query: 1855 RLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPC--TNA 2028
V + K+ + NT + P I YHP QP + NPC N
Sbjct: 3427 TRTVEKGNKYDGSNRQTLVNTTHR--PFDIHVYHPYRQP----------IVSNPCGTNNG 3474
Query: 2029 DCEGMCILSKDNGGFGVGYKCACP 2100
C +C++ G G+ C CP
Sbjct: 3475 GCSHLCLIKPG----GKGFTCECP 3494
Score = 222 bits (565), Expect = 2e-55
Identities = 196/737 (26%), Positives = 297/737 (39%), Gaps = 60/737 (8%)
Frame = +1
Query: 11503 DVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRC-NDGKCIPG 11679
D FRC SG CIP W CD DC D++DE+ C T C + F+C ++G+CIP
Sbjct: 29 DSAHFRCG-SGHCIPADWRCDGTKDCSDDADEI--GCAVVT--CQQGYFKCQSEGQCIPS 83
Query: 11680 SKVCDGTIQCSDGLDESQ-------------CTLRRCLPGHRQ----------------- 11769
S VCD C DG DE Q C+ +C+P +
Sbjct: 84 SWVCDQDQDCDDGSDERQDCSQSTCSSHQITCSNGQCIPSEYRCDHVRDCPDGADENDCQ 143
Query: 11770 --------CDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFECANSVCIPRK 11925
CD+G C + CD K DC +++DE++C ++ C EF C N CIPR
Sbjct: 144 YPTCEQLTCDNGACYNTSQKCDWKVDCRDSSDEINCTEI----CLHNEFSCGNGECIPRA 199
Query: 11926 FMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDE 12105
++ SDE + C C +F C R C+ +C+G +DC N D
Sbjct: 200 YVCDHDNDCQDGSDEHA--CNYPTCG-GYQFTCPSGR-CIYQNWVCDGEDDCKDNGDED- 254
Query: 12106 HLSMCSSFSEYGDCSSDQFKC-ANGKCVNGTVACDRKDDCGDASDEIGCS--KHGGKTSC 12276
S + CS ++ C +G+C++ CD DC DE S K+ T C
Sbjct: 255 --GCESGPHDVHKCSPREWSCPESGRCISIYKVCDGILDCPGREDENNTSTGKYCSMTLC 312
Query: 12277 EAFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGS 12456
A C++ C + G C C G+ + + C++ D+C C Q C + G
Sbjct: 313 SAL----NCQYQCHETPYGGACFCPPGYIINHNDSRTCVEFDDCQIWGICDQKCESRPGR 368
Query: 12457 YLCRCHEDYENNVVVGSMTGKDCRAK---GDAANVMIGADDSLVQLSLHGSGTNRHXXXX 12627
+LC C E Y G+ C+A G+A+ + D L+ +HG
Sbjct: 369 HLCHCEEGYILE------RGQYCKANDSFGEASIIFSNGRDLLIG-DIHGRSFRILVESQ 421
Query: 12628 XXXXXXXXXXXXXXPRKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTA 12807
R ++W D + ++ S NG E + V+ P
Sbjct: 422 NRGVAVGVAFHYHLQR---VFWTDTVQNKVF-SVDINGLNIQEVLNVSVE------TPEN 471
Query: 12808 IAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGH 12987
+AVD+ +++ N ID N DG Y ++ +
Sbjct: 472 LAVDWVNNKIYLVETKVN---------------RIDMVNL--------DGSYRVTLITEN 508
Query: 12988 LQQPTALITAPSAGRICYSD---AGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGK 13158
L P + P+ G + +SD K+E A MDG++R+ +VK + P + +D
Sbjct: 509 LGHPRGIAVDPTVGYLFFSDWESLSGEPKLERAFMDGSNRKDLVKTKLGWPAGVTLDM-I 567
Query: 13159 GNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHI---PYAVDVFENHIYWLSRESKTLYVQ 13329
R+YWVD ++ ++ V DG +R TVVH + P+ V +FE +++ +
Sbjct: 568 SKRVYWVDSRFDYIETVTYDGIQRKTVVHGGSLIPHPFGVSLFEGQVFFTDWTKMAVLKA 627
Query: 13330 DKFGRGRVSVL--ASDLEDGHTV--RVSQKYAKDTQRTVSGCERAQCSHLCVSLPST--- 13488
+KF V AS G TV + Q YA + + +G C +CV T
Sbjct: 628 NKFTETNPQVYYQASLRPYGVTVYHSLRQPYATNPCKDNNG----GCEQVCVLSHRTDND 683
Query: 13489 --GFACLCPDGIVPQLD 13533
GF C C G QLD
Sbjct: 684 GLGFRCKCTFGF--QLD 698
Score = 140 bits (353), Expect = 9e-31
Identities = 101/332 (30%), Positives = 129/332 (38%), Gaps = 10/332 (3%)
Frame = +1
Query: 10879 CTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRP 11058
C F CG CIP W CDG DC D +DE G C C G F
Sbjct: 28 CDSAHFRCGS--GHCIPADWRCDGTKDCSDDADEIG---CAVVTCQQGYF---------- 72
Query: 11059 FQIXXXXXXXXXXXXEQNCDKACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEADTLC 11238
KC + G+CIP + SDE
Sbjct: 73 ----------------------------KCQSEGQCIPSSWVCDQDQDCDDGSDERQDCS 104
Query: 11239 MSAERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXET----PECAQIECKKGWTRCSS 11406
S C++ + C+N +CI +R E P C Q+ C G
Sbjct: 105 QS---TCSSHQITCSNGQCIPSEYRCDHVRDCPDGADENDCQYPTCEQLTCDNG------ 155
Query: 11407 SYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMCDTENDCGD 11586
C C+ + DCRD+SDE C EF C +G+CIPR ++CD +NDC D
Sbjct: 156 --ACYNTSQKCDWKVDCRDSSDE--INCTEICLHNEFSCG-NGECIPRAYVCDHDNDCQD 210
Query: 11587 NSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQC-----TLRRC 11751
SDE +C T C +F C G+CI + VCDG C D DE C + +C
Sbjct: 211 GSDE--HACNYPT--CGGYQFTCPSGRCIYQNWVCDGEDDCKDNGDEDGCESGPHDVHKC 266
Query: 11752 LPGHRQC-DDGTCIAEHKWCDRKKDCPNAADE 11844
P C + G CI+ +K CD DCP DE
Sbjct: 267 SPREWSCPESGRCISIYKVCDGILDCPGREDE 298
Score = 139 bits (351), Expect = 2e-30
Identities = 115/414 (27%), Positives = 164/414 (38%), Gaps = 19/414 (4%)
Frame = +1
Query: 8389 NFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNR-RCIDSAKKCNH 8565
+F+CG G CI CD DC+D +DE C +C + Y C + +CI S+ C+
Sbjct: 32 HFRCGSGHCIPADWRCDGTKDCSDDADEIG--CAVVTCQQGYFKCQSEGQCIPSSWVCDQ 89
Query: 8566 IDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHD-EQVSDESLATCPG 8742
DC DGSDE S C+ CSNG CI CD DC D +D TC
Sbjct: 90 DQDCDDGSDERQDCSQSTCSSHQITCSNGQCIPSEYRCDHVRDCPDGADENDCQYPTCEQ 149
Query: 8743 LPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCI 8922
L D C + CD DC D +DE + C + C + C +G CI
Sbjct: 150 LTCD----------NGACYNTSQKCDWKVDCRDSSDE--INC-TEICLHNEFSCGNGECI 196
Query: 8923 PETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXX 9102
P + CD DNDC DG DE N G Y F C + +CI + ++
Sbjct: 197 PRAYVCDHDNDCQDGSDEHACNYPTCGG-------YQFTCPSGRCIYQNWVCDGEDDCKD 249
Query: 9103 XXXXHSRHGCGN-----RTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDES 9267
GC + C+ +E+ C + + CI +CDG + C G EDE+
Sbjct: 250 NG---DEDGCESGPHDVHKCSPREWSCPESGR-------CISIYKVCDGILDCPGREDEN 299
Query: 9268 TELCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDC-------LDGSDEHANCTYSSCQP 9426
+ K C+ CS +C + E C ++ +D + CQ
Sbjct: 300 N---TSTGKYCSM--TLCSALNCQYQCHETPYGGACFCPPGYIINHNDSRTCVEFDDCQ- 353
Query: 9427 DFFQCANHKCV--PNSWKCDGNDDCEDG---SDEKDCPKNSASAQKASKCSNGQ 9573
+ + KC P C CE+G + C N + + + SNG+
Sbjct: 354 -IWGICDQKCESRPGRHLC----HCEEGYILERGQYCKANDSFGEASIIFSNGR 402
Score = 130 bits (327), Expect = 9e-28
Identities = 78/229 (34%), Positives = 110/229 (47%), Gaps = 15/229 (6%)
Frame = +1
Query: 9274 LCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCANH- 9450
L +EC+ FRC + HCI + W CDG DC D +DE C +CQ +F+C +
Sbjct: 20 LAPASGQECDSAHFRCGSGHCIPADWRCDGTKDCSDDADE-IGCAVVTCQQGYFKCQSEG 78
Query: 9451 KCVPNSWKCDGNDDCEDGSDEK-DCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRN 9627
+C+P+SW CD + DC+DGSDE+ DC + S CS+ Q C++G+CI CD
Sbjct: 79 QCIPSSWVCDQDQDCDDGSDERQDCSQ--------STCSSHQITCSNGQCIPSEYRCDHV 130
Query: 9628 FDCTDRSDESSLCFIDECSLAEKPLCEQKCMD--------MKIGYKCDCFEGFAIDISDQ 9783
DC D +DE+ + P CEQ D K +K DC D SD+
Sbjct: 131 RDCPDGADEND---------CQYPTCEQLTCDNGACYNTSQKCDWKVDC-----RDSSDE 176
Query: 9784 KSC-----HNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSC 9915
+C HN C G +C + +Y C + Q SD+H+C
Sbjct: 177 INCTEICLHNEFSCGNG------ECIPR--AYVCDHDNDCQDGSDEHAC 217
Score = 90.1 bits (222), Expect = 1e-15
Identities = 81/286 (28%), Positives = 113/286 (39%), Gaps = 10/286 (3%)
Frame = +1
Query: 11743 RRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFEC-ANSVCIP 11919
+ C H +C G CI CD KDC + ADE+ C V TC F+C + CIP
Sbjct: 26 QECDSAHFRCGSGHCIPADWRCDGTKDCSDDADEIGCAVV---TCQQGYFKCQSEGQCIP 82
Query: 11920 RKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFS 12099
++ SDE +C + C +H C N C P+++
Sbjct: 83 SSWVCDQDQDCDDGSDE-RQDCSQSTCS-------SHQITCSN--------GQCIPSEYR 126
Query: 12100 DEHLSMCSSFSEYGDC---SSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSK--HGG 12264
+H+ C ++ DC + +Q C NG C N + CD K DC D+SDEI C++
Sbjct: 127 CDHVRDCPDGADENDCQYPTCEQLTCDNGACYNTSQKCDWKVDCRDSSDEINCTEICLHN 186
Query: 12265 KTSCEAFGNNGGC---KHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNN-TCTQ 12432
+ SC NG C ++C D C+DG S + + C G TC
Sbjct: 187 EFSC----GNGECIPRAYVCDHDND-----CQDG------SDEHACNYPTCGGYQFTCPS 231
Query: 12433 LCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADD 12570
RC Y+N V G DC+ GD G D
Sbjct: 232 ----------GRC--IYQNWVCDGE---DDCKDNGDEDGCESGPHD 262
Score = 84.7 bits (208), Expect = 6e-14
Identities = 55/181 (30%), Positives = 86/181 (47%), Gaps = 25/181 (13%)
Frame = +1
Query: 3925 SGRQCSSDQFKCGNGRCILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACEN 4104
SG++C S F+CG+G CI +W CDG DC SD++ E GC C + C++
Sbjct: 24 SGQECDSAHFRCGSGHCIPADWRCDGTKDC---SDDADEIGCAVV----TCQQGYFKCQS 76
Query: 4105 DQETCIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCS--------FKC---HNSPN 4251
+ + CIP +CD C G+DE C++ CS+ + CS ++C + P+
Sbjct: 77 EGQ-CIPSSWVCDQDQDCDDGSDERQDCSQSTCSSHQITCSNGQCIPSEYRCDHVRDCPD 135
Query: 4252 G--------PIC---SCPFGEQLVNKTKCEPENECLDSS---SCSQRCKDEKHGFTCSCD 4389
G P C +C G KC+ + +C DSS +C++ C + F+C
Sbjct: 136 GADENDCQYPTCEQLTCDNGACYNTSQKCDWKVDCRDSSDEINCTEICLHNE--FSCGNG 193
Query: 4390 E 4392
E
Sbjct: 194 E 194
Score = 46.6 bits (109), Expect = 0.018
Identities = 26/86 (30%), Positives = 38/86 (43%), Gaps = 3/86 (3%)
Frame = +1
Query: 12109 LSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSK---HGGKTSCE 12279
L C + + +C S F+C +G C+ CD DC D +DEIGC+ G C+
Sbjct: 16 LVACLAPASGQECDSAHFRCGSGHCIPADWRCDGTKDCSDDADEIGCAVVTCQQGYFKCQ 75
Query: 12280 AFGNNGGCKHICTDVRDGFYCHCRDG 12357
+ G +C +D C DG
Sbjct: 76 SEGQCIPSSWVCDQDQD-----CDDG 96
>gi|32816597|gb|AAP88586.1| glycoprotein receptor gp330/megalin
precursor [Homo sapiens]
Length = 4655
Score = 2533 bits (6564), Expect = 0.0
Identities = 1521/4609 (33%), Positives = 2304/4609 (49%), Gaps = 100/4609 (2%)
Frame = +1
Query: 136 VNTASSVCNENDFRC-NDGKCIRTEWXXXXXXXXXXXXXXXXX-PHPGCKSDQWQCDTYT 309
+ A C + F+C ++G+CI + W C S Q C
Sbjct: 60 IGCAVVTCQQGYFKCQSEGQCIPSSWVCDQDQDCDDGSDERQDCSQSTCSSHQITCS--- 116
Query: 310 WHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKY 489
+ CI RCD++ DC DG+DE DC T + + D C++ S+KCD K
Sbjct: 117 --NGQCIPSEYRCDHVRDCPDGADENDCQYPTCEQ------LTCDNGACYNTSQKCDWKV 168
Query: 490 DCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKC 669
DCRD SDE + C+ C +F C + +CI +++VCD DC DGSDE C + C
Sbjct: 169 DCRDSSDEIN-CTE---ICLHNEFSCGNG-ECIPRAYVCDHDNDCQDGSDE-HACNYPTC 222
Query: 670 TANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGE-----YRCPPGKWNCPGTGHCIDQ 834
+F C + RC + + CD DDC DN DED C ++C P +W+CP +G CI
Sbjct: 223 GGYQFTCPSGRCIYQNWVCDGEDDCKDNGDEDGCESGPHDVHKCSPREWSCPESGRCISI 282
Query: 835 LKLCDGSKDCADGADEQQ------CSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRF 996
K+CDG DC DE CS LC +L CQ CH +P+GG C CP GY ++
Sbjct: 283 YKVCDGILDCPGREDENNTSTGKYCSMTLCSALNCQYQCHETPYGGACFCPPGYIINHND 342
Query: 997 HRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNA 1176
RTC + ++C +G CDQ C + C C + ++ D+ SN
Sbjct: 343 SRTCVEFDDCQIWGICDQKCESRPGRHLCHCEEGYILERGQYCKANDSFGEASIIFSNGR 402
Query: 1177 DKMKLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSAD 1356
D + + R + +N V G+ F Y +++FWTD + + FS D
Sbjct: 403 DLLIGDIHGRSFRILVESQNRGVAV----------GVAFHYHLQRVFWTDTVQNKVFSVD 452
Query: 1357 VDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADG 1536
++ I ++ +S+++ P LAVDW+ N +Y++E+ RID+ + DG R L+ +
Sbjct: 453 INGLN-IQEVLNVSVET---PENLAVDWVNNKIYLVETKVNRIDMVNLDGSYRVTLITEN 508
Query: 1537 LTLPLDIALDPLRGEMFFTN------QLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITA 1698
L P IA+DP G +FF++ + KLE A MDG+NR+ LV T +G+ +D+ +
Sbjct: 509 LGHPRGIAVDPTVGYLFFSDWESLSGEPKLERAFMDGSNRKDLVKTKLGWPAGVTLDMIS 568
Query: 1699 KRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVE 1878
KRVYWVD + D +E++ Y G R+ V G +++PHPFG++LF+ +++TDWT++ V++
Sbjct: 569 KRVYWVDSRFDYIETVTYDGIQRKTVVHGGSLIPHPFGVSLFEGQVFFTDWTKMAVLKAN 628
Query: 1879 KFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPC--TNADCEGMCIL 2052
KF ++ ++ P G++ YH + QP NPC N CE +C+L
Sbjct: 629 KFTETNPQVYYQA--SLRPYGVTVYHSLRQP----------YATNPCKDNNGGCEQVCVL 676
Query: 2053 SKDNGGFGVGYKCACPIGQKLVNGKR-CIDSIDYLLFSSNKIVRGIFPEINEKALAEAVL 2229
S G+G++C C G +L +R CI ++L+FSS +RGI ++ + + ++
Sbjct: 677 SHRTDNDGLGFRCKCTFGFQLDTDERHCIAVQNFLIFSSQVAIRGIPFTLSTQE--DVMV 734
Query: 2230 PISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMS 2409
P+S +G+ F D ++ F++D+ + I++ + DG G + + + S++
Sbjct: 735 PVSGNPSFFVGIDF----DAQDSTIFFSDMSKHMIFKQKIDGTGREILAANRVENVESLA 790
Query: 2410 FDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKGLLFY 2589
FDWISK LY+ D+ S+ V+++ + RR ++ L +P SVVVHP+ G LF+
Sbjct: 791 FDWISKNLYWTDSHYKSISVMRLADK--------TRRTVVQYLNNPRSVVVHPFAGYLFF 842
Query: 2590 AEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGK 2769
+ RPA I R DG + + NTTLG P+ +AID+A +RL W D I FDG
Sbjct: 843 TDWFRPAKIMRAWSDGSHLLPVINTTLGWPNGLAIDWAASRLYWVDAYFDKIEHSTFDGL 902
Query: 2770 NVVKLDIDNPI--PVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFS 2943
+ +L + P + I E++++ R +I RV K +GG ++R A I
Sbjct: 903 DRRRLGHIEQMTHPFGLAIFGEHLFFTDWRLGAIIRVRKADGGEMTVIRSGIA---YILH 959
Query: 2944 LKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINKENNHS 3123
LK+ Q + + C+ CF P+ + C C G + N+ +
Sbjct: 960 LKSYDVNIQTGSNACNQPTHPNGDCSHFCFPVPN------FQRVCGCPYGMRL-ASNHLT 1012
Query: 3124 CQKDPA-EKIEQLCSSNSTQFQCKNGRCIPKEWKCDGENDCLDESDEIDEKGDKCFH-ET 3297
C+ DP E + C S F CKNGRC+P + CDG +DC D SDE C
Sbjct: 1013 CEGDPTNEPPTEQCGLFS--FPCKNGRCVPNYYLCDGVDDCHDNSDE-----QLCGTLNN 1065
Query: 3298 ECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNHRCI 3477
C+ + C + + CIPA C C ++ CDNH+CI
Sbjct: 1066 TCSSSAFTCGHGE-CIPAHWRCDKRNDCVDGSDEH--NCPTHAPASCLDTQYTCDNHQCI 1122
Query: 3478 PEQWKXXXXXXXXXXXXEKLEMCGNA-TCAANQFSCANGRCIPIYWLCDGDNDCYDGTDE 3654
+ W EK C + TC +QF+C N RCI + ++CDGD DC DG+DE
Sbjct: 1123 SKNWVCDTDNDCGDGSDEK--NCNSTETCQPSQFNCPNHRCIDLSFVCDGDKDCVDGSDE 1180
Query: 3655 DKERCPPVQCSALQFRCANGRQCVPLRNHXXXXXXXXXXXXXXXXAVTAES-CTPDQFKC 3831
C + C+A QF+CA+G +C+ + N C D+F+C
Sbjct: 1181 --VGCV-LNCTASQFKCASGDKCIGVTNRCDGVFDCSDNSDEAGCPTRPPGMCHSDEFQC 1237
Query: 3832 VSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKCGNGRCILNNWLCDGEND 4011
G+CIP W+ SDE C + C S F C NG CI WLCD +ND
Sbjct: 1238 QEDGICIPNFWECDGHPDCLYGSDEHN-ACVP-KTCPSSYFHCDNGNCIHRAWLCDRDND 1295
Query: 4012 CGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGGRCA 4191
CGD SDE + C T +CP C C+ L +CDG CP GTDE C
Sbjct: 1296 CGDMSDE---KDCPTQ--PFRCPSWQWQCLG-HNICVNLSVVCDGIFDCPNGTDESPLCN 1349
Query: 4192 RDLCSADRAGCSFKCHNSPNGPICSCPFGEQLVNKTK-CEPENECLDSSSCSQRCKDEKH 4368
+ CS GC+ +C P G C CP G L N +K CE +EC SCSQ C + +
Sbjct: 1350 GNSCSDFNGGCTHECVQEPFGAKCLCPLGFLLANDSKTCEDIDECDILGSCSQHCYNMRG 1409
Query: 4369 GFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGAIVENA-- 4542
F CSCD GY L+ D RTCKV + + + V+++N+I +D H ++VEN
Sbjct: 1410 SFRCSCDTGYMLESDGRTCKVTAS-ESLLLLVASQNKII-ADSVTSQVHNIYSLVENGSY 1467
Query: 4543 -IALAWDSLTDRIYWSDIREKKILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVD 4719
+A+ +DS++ RI+WSD + K SA +NGT+ V + +TE IA+DWVGRNLYW D
Sbjct: 1468 IVAVDFDSISGRIFWSDATQGKTWSAFQNGTDRRVVFDSSIILTETIAIDWVGRNLYWTD 1527
Query: 4720 SSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKG--VMFWTDWGQNPCIERASMDG 4893
+L TIEV+ + D RT+L+ +N++ PRG+A+DPR ++FW+DWG +P IERASMDG
Sbjct: 1528 YALETIEVSKI-DGSHRTVLISKNLTNPRGLALDPRMNEHLLFWSDWGHHPRIERASMDG 1586
Query: 4894 TDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPH 5073
+ R +IV+ KI+WP + +DY +YF DS LD++DF +Y+G R QV+AS ++HP+
Sbjct: 1587 SMRTVIVQDKIFWPCGLTIDYPNRLLYFMDSYLDYMDFCDYNGHHRRQVIASDLIIRHPY 1646
Query: 5074 ALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPC 5253
AL +FED +Y++DR +++ K+ G S + LG+VAVHP QP NPC
Sbjct: 1647 ALTLFEDSVYWTDRATRRVMRANKWHGGNQSVV-MYNIQWPLGIVAVHPSKQPN-SVNPC 1704
Query: 5254 STNPCSHLCLLNNKNT--FTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNVFGIEMNSA 5427
+ + CSHLCLL+++ ++C CP G L C+ D +PFL+ +++ +FGI +N
Sbjct: 1705 AFSRCSHLCLLSSQGPHFYSCVCPSGWSLSPDLLNCLRDDQPFLITVRQHIIFGISLNPE 1764
Query: 5428 SEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNG 5607
+ MVP++G+ N D +D + ++ +E+ I+R +G
Sbjct: 1765 VKSND----AMVPIAGIQNGLDVEFDDAEQYIYWVENPGE------------IHRVKTDG 1808
Query: 5608 GNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGK-QYRSVILSNDQSXX 5784
N+T S ++ + L DW RNL N TQ+IE++ G +YR +++ND +
Sbjct: 1809 TNRTVFASISMVGPSMNLALDWISRNLYSTNPRTQSIEVLTLHGDIRYRKTLIANDGTAL 1868
Query: 5785 XXXXXXXXXXXXXKGYVFWLDRG-GGAADAKVARAGLDGSNPLVIASNDLAELDHIAIDT 5961
+G ++W D+G AK+A A +DG++ + + +L L+ + +D
Sbjct: 1869 GVGFPIGITVDPARGKLYWSDQGTDSGVPAKIASANMDGTSVKTLFTGNLEHLECVTLDI 1928
Query: 5962 TNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAFDSIE-VA 6138
++Y++ G I DG DR +L P G+A + L+Y D ++ IE V
Sbjct: 1929 EEQKLYWAVTGRGVIERGNVDGTDR-MILVHQLSHPWGIAVHDSFLYYTDEQYEVIERVD 1987
Query: 6139 TINGDSQPPQWTHFKKDVENLANIKALQPR-ASSSGHPCHINNGNCDHICIPLMFAQRTC 6315
G ++ + +V NL ++ R A+ S + C N C IC+P+ +C
Sbjct: 1988 KATGANK----IVLRDNVPNLRGLQVYHRRNAAESSNGCSNNMNACQQICLPVPGGLFSC 2043
Query: 6316 TCANGY-VKDGQTSCKLFDESFVIVATKTKVIGYPIDETQSKGVAMEPIGGLSITG--VD 6486
CA G+ + SC ++ SF++V+ + + G+ + E M P+ G VD
Sbjct: 2044 ACATGFKLNPDNRSCSPYN-SFIVVSMLSAIRGFSL-ELSDHSETMVPVAGQGRNALHVD 2101
Query: 6487 YDYESKTIYVAEASGI---NKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINYNMYF 6657
D S IY + S + I SS ++ IG ++ +A+DW+ N+YF
Sbjct: 2102 VDVSSGFIYWCDFSSSVASDNAIRRIKPDGSSLMNIVTHGIGENGVRGIAVDWVAGNLYF 2161
Query: 6658 INHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQRSFLD 6837
N T IEV +++ TYR++LL + P I VDP +RYL+WAD GQ+P I+RSFLD
Sbjct: 2162 TNAFVSETLIEVLRINTTYRRVLLKVTVDMPRHIVVDPKNRYLFWADYGQRPKIERSFLD 2221
Query: 6838 GSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPELVR--SDIASAA 7011
+ R V+VS GI P L VD + +YW D +D I R+R G E++R S +
Sbjct: 2222 CTNRTVLVSEGIVTPRGLAVDRSDGYVYWVDDSLDIIARIRINGENSEVIRYGSRYPTPY 2281
Query: 7012 GVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRAS 7191
G+ + ++ W D L+K+F+A+ +P T PT + ++ + DV +F QPR
Sbjct: 2282 GITVFENSIIWVDRNLKKIFQASKEPENTE---PPTVIRDNINWLRDVTIFDKQVQPR-- 2336
Query: 7192 SPCQITDNL---RKSPCTQLCFATPGTQTPTCSCARGVLK--GRTCE-EPDTYIMFSDGD 7353
SP ++ +N C+ LCFA PG TP C CA G L+ G+ C + +++F+ +
Sbjct: 2337 SPAEVNNNPCLENNGGCSHLCFALPGLHTPKCDCAFGTLQSDGKNCAISTENFLIFALSN 2396
Query: 7354 KIIDVAIEPDVKASRPLKDPFPEIS---NLQTFDVDVNLRRVYFVVESPVGVN-ISWFSM 7521
+ + ++P+ + PF I+ + + D D R+YF GV IS+ ++
Sbjct: 2397 SLRSLHLDPENHSP-----PFQTINVERTVMSLDYDSVSDRIYFTQNLASGVGQISYATL 2451
Query: 7522 NNAENPRLVFGASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTIA 7701
++ + V A I + DW+T++IY++ + ++ G + + IA
Sbjct: 2452 SSGIHTPTVI-------ASGIGTADGIAFDWITRRIYYSDYLNQMINSMAEDGSNRTVIA 2504
Query: 7702 SGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIA 7881
A+ +DPC G L+W+D + T +IER+ L G R IV+ S+ +P+ +
Sbjct: 2505 RVPKPRAIVLDPCQGYLYWAD--WDTHA-----KIERATLGGNFRVPIVNSSLVMPSGLT 2557
Query: 7882 VDFRNQKIYWADVNRLNIEVADYDGQNRKVIASG-YRAKSLDIWDRWLYMSDPLSNGVFR 8058
+D+ +YW D + IE + G +R+VI + A L ++ +++Y +D + ++R
Sbjct: 2558 LDYEEDLLYWVDASLQRIERSTLTGVDREVIVNAAVHAFGLTLYGQYIYWTDLYTQRIYR 2617
Query: 8059 IDKESGSG----LENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQL 8226
+K GSG N++S R + V+ + Q CN C+ NGGC +
Sbjct: 2618 ANKYDGSGQIAMTTNLLSQPR--------GINTVVKNQKQQCN----NPCEQFNGGCSHI 2665
Query: 8227 CTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSEPAKECLPPYNFQCGD 8406
C G ++ QC + L C++ A +F C +
Sbjct: 2666 CAP-----GPNGAECQCPHEGNWYLANNR-----KHCIVDNGERCGAS------SFTCSN 2709
Query: 8407 GSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHIDDCGDG 8586
G CI CD+ DC D SDE + C +C C N RC+ + +C++ +DCGDG
Sbjct: 2710 GRCISEEWKCDNDNDCGDGSDEMESVCALHTCSPTAFTCANGRCVQYSYRCDYYNDCGDG 2769
Query: 8587 SDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPGLPIDCRGV 8766
SDE C A F C+N CI + +C+G ++CHD SDE CP C+
Sbjct: 2770 SDEAGCLFRDCNATTEFMCNNRRCIPREFICNGVDNCHDNNTSDEK--NCPDRT--CQSG 2825
Query: 8767 KVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCIPETWQCDG 8946
+C N+NICI LCDG +DCGD +DEN +C C+ +C SGRCIP+ W CD
Sbjct: 2826 YTKCHNSNICIPRVYLCDGDNDCGDNSDENPTYCTTHTCSSSEFQCASGRCIPQHWYCDQ 2885
Query: 8947 DNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXXXXXXHSRH 9126
+ DC D DE +C + ++ C+ D F+CD +CI +I RH
Sbjct: 2886 ETDCFDASDEP-ASCGHS--ERTCLADE-FKCDGGRCIPSEWICDGDNDCGDMSDEDKRH 2941
Query: 9127 GCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECNK 9306
C N+ C+D EF C ++ P CIP++W+CDGDV C G DE+ + + C++
Sbjct: 2942 QCQNQNCSDSEFLCVNDRP---PDRRCIPQSWVCDGDVDCTDGYDENQNCTR---RTCSE 2995
Query: 9307 GEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCANHKCVPNSWKCDGN 9486
EF C CI + CD NDC D SDE C Y +CQ + F C N +C+ ++ CD +
Sbjct: 2996 NEFTCGYGLCIPKIFRCDRHNDCGDYSDERG-CLYQTCQQNQFTCQNGRCISKTFVCDED 3054
Query: 9487 DDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLC 9666
+DC DGSDE C +F+C +G CI+ K+C+ DC D SDE C
Sbjct: 3055 NDCGDGSDEL----MHLCHTPEPTCPPHEFKCDNGRCIEMMKLCNHLDDCLDNSDEKG-C 3109
Query: 9667 FIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNECYEGISGCSQKCD 9846
I+EC C+ C D + C C G+ + +SD+++C +++EC E CSQKC+
Sbjct: 3110 GINECHDPSISGCDHNCTDTLTSFYCSCRPGYKL-MSDKRTCVDIDECTEMPFVCSQKCE 3168
Query: 9847 DKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYELAAQGFD 10026
+ IGSY C C GY D +C++ EP+ + +N++Y+R ++IDG Y L +G D
Sbjct: 3169 NVIGSYICKCAPGYLREPDGKTCRQNS-NIEPYLIFSNRYYLRNLTIDGYFYSLILEGLD 3227
Query: 10027 NVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDWVGR 10206
NVV+LD D EK+ Y ID + + R+ L++ + ET++ H + E +AVDWV R
Sbjct: 3228 NVVALDFDRVEKRLYWIDTQRQVIERMFLNKTNK-----ETIINHRLPAAESLAVDWVSR 3282
Query: 10207 KLYMLNRQERSIRVCELDGRFCKTLIRDRIQ--------QPKAIVVHPGKGYLFFTEWSL 10362
KLY L+ + + V +L+G + L + + P+ + +HP GYL++ +W
Sbjct: 3283 KLYWLDARLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLYWADWGH 3342
Query: 10363 QPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGN 10542
+ YIGR+ +DG+ + + L WPN I IDY +D L+W DAHL I + D +G+
Sbjct: 3343 RAYIGRVGMDGTNKSV-----IISTKLEWPNGITIDYTNDLLYWADAHLGYIEYSDLEGH 3397
Query: 10543 GRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDLRIV 10722
R + H ++ +F+D +YW DWN R V + +K+ G N L T P D+ +
Sbjct: 3398 HRHTVYDGALPHPFAITIFEDTIYWTDWNTRTVEKGNKYDGSNRQTLVNTTHRPFDIHVY 3457
Query: 10723 HPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQF--VLLSDQKTCEPNCTERQF 10896
HP RQP NPCG NNGGCSHLCLI GG G+TC CPD F + LS C P C+ QF
Sbjct: 3458 HPYRQPIVSNPCGTNNGGCSHLCLIKPGGKGFTCECPDDFRTLQLSGSTYCMPMCSSTQF 3517
Query: 10897 ACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRPFQIXXX 11076
C ++ KCIP W CDG+ DC DGSDE ++C QR C +G+FQC++ NCT P +
Sbjct: 3518 LCANNE-KCIPIWWKCDGQKDCSDGSDE--LALCPQRFCRLGQFQCSDGNCTSPQTLCNA 3574
Query: 11077 XXXXXXXXXEQN--CDK-ACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEADTLCMSA 11247
E C+ CD ++C A RCIP + SDE + C A
Sbjct: 3575 HQNCPDGSDEDRLLCENHHCDSNEWQC-ANKRCIPESWQCDTFNDCEDNSDEDSSHC--A 3631
Query: 11248 ERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXE-TPEC-AQIECKKGWTR--CSSSYR 11415
R C +FRC N +CI +AW+ E EC + +T C ++YR
Sbjct: 3632 SRTCRPGQFRCANGRCIPQAWKCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFSCKTNYR 3691
Query: 11416 CIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSD 11595
CIP WA CNG DDCRDNSDE TC VG+FRC + CIP RW CD +NDCGDNSD
Sbjct: 3692 CIPKWAVCNGVDDCRDNSDEQGCEERTCHPVGDFRC-KNHHCIPLRWQCDGQNDCGDNSD 3750
Query: 11596 ELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQCD 11775
E + + R C+ESEFRC + +CIP +CD C D DE C +R C P + QC
Sbjct: 3751 EENCA----PRECTESEFRCVNQQCIPSRWICDHYNDCGDNSDERDCEMRTCHPEYFQCT 3806
Query: 11776 DGTCIAEHKWCDRKKDCPNAADELHCED--VSRRTCSPFEFECANSVCIPRKFMXXXXXX 11949
G C+ CD DC +A+DE C C FEC N VCIP +
Sbjct: 3807 SGHCVHSELKCDGSADCLDASDEADCPTRFPDGAYCQATMFECKNHVCIPPYWKCDGDDD 3866
Query: 11950 XXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSF 12129
SDE C C+ P RFRC ++R C+ ++CNG +DCG D +DE C
Sbjct: 3867 CGDGSDEELHLCLDVPCNSPNRFRCDNNR-CIYSHEVCNGVDDCG--DGTDETEEHCRKP 3923
Query: 12130 SEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKH 12309
+ C+ ++KC NG C+ CD DDCGD SDE+GC+K +T E C+
Sbjct: 3924 TP-KPCTEYEYKCGNGHCIPHDNVCDDADDCGDWSDELGCNKGKERTCAENI-----CEQ 3977
Query: 12310 ICTDVRD-GFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGSYLCRCHEDYE 12486
CT + + GF C C GF + C+DI+EC TC Q C NTKGSY C C + +
Sbjct: 3978 NCTQLNEGGFICSCTAGFETNVFDRTSCLDINECEQFGTCPQHCRNTKGSYECVCADGFT 4037
Query: 12487 NNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXXX 12666
+ + GK C A+G + +++ + + + +L + +
Sbjct: 4038 S---MSDRPGKRCAAEGSSPLLLLPDNVRIRKYNLSSERFSEYLQDEEYIQAVDYDWDPE 4094
Query: 12667 XPRKELMYWI---DGSE-RTIYRSAIANGNQSHEGQKLDVDFAAMGVV-PTAIAVDYTTG 12831
++Y+ +GS I R+ I N +VD V+ P IAVD+
Sbjct: 4095 DIGLSVVYYTVRGEGSRFGAIKRAYIPNFESGRNNLVQEVDLKLKYVMQPDGIAVDWVGR 4154
Query: 12832 NLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALI 13011
+++ + V + KR I V DGRY K +++ L QP A+
Sbjct: 4155 HIYWSDV-----------KNKR------------IEVAKLDGRYRKWLISTDLDQPAAIA 4191
Query: 13012 TAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKY 13191
P G + ++D G K+E A M+G R I+V + + PT ++ID +RIYW D K
Sbjct: 4192 VNPKLGLMFWTDWGKEPKLESAWMNGEDRNILVFEDLGWPTGLSIDYLNNDRIYWSDFKE 4251
Query: 13192 RRVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSRESKTLYVQDKFGRGR------V 13353
++ + DG++R + + PY++D+FE+ +YW+S+E ++ Q+KFG+G+ V
Sbjct: 4252 DVIETIKYDGTDRRVIAKEAMNPYSLDIFEDQLYWISKEKGEVWKQNKFGQGKKEKTLVV 4311
Query: 13354 SVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTGFACLCPDG--IVPQ 13527
+ + + H +R + ++V + CSHLC+ P G++C CP G +
Sbjct: 4312 NPWLTQVRIFHQLRYN--------KSVPNLCKQICSHLCLLRPG-GYSCACPQGSSFIEG 4362
Query: 13528 LDGSCATQHVEALTMPKQCKCTNGGKCRLDGS----CECTSDFEGDQCE 13662
C + +P C+C +GG C D + C+C S + G CE
Sbjct: 4363 STTECDAAIELPINLPPPCRCMHGGNCYFDETDLPKCKCPSGYTGKYCE 4411
Score = 399 bits (1024), Expect = e-108
Identities = 301/1086 (27%), Positives = 485/1086 (43%), Gaps = 32/1086 (2%)
Frame = +1
Query: 3169 NSTQFQCKNGRCIPKEWKCDGENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKKCIP 3348
+S F+C +G CIP +W+CDG DC D++DEI C T C + KC++ +CIP
Sbjct: 29 DSAHFRCGSGHCIPADWRCDGTKDCSDDADEIG-----CAVVT-CQQGYFKCQSEGQCIP 82
Query: 3349 AQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXX 3528
+ +D + C++ + C N +CIP +++
Sbjct: 83 SSWVCDQDQDCDDGSDER----QDCSQSTCSSHQITCSNGQCIPSEYRCDHVRDCPDGAD 138
Query: 3529 EKLEMCGNATCAANQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCA 3708
E C TC Q +C NG C CD DC D +DE C + C +F C
Sbjct: 139 E--NDCQYPTC--EQLTCDNGACYNTSQKCDWKVDCRDSSDE--INCTEI-CLHNEFSCG 191
Query: 3709 NGRQCVPLRNHXXXXXXXXXXXXXXXXAVTAESCTPDQFKCVSSGLCIPASWKXXXXXXX 3888
NG +C+P A +C QF C SG CI +W
Sbjct: 192 NG-ECIP--RAYVCDHDNDCQDGSDEHACNYPTCGGYQFTC-PSGRCIYQNWVCDGEDDC 247
Query: 3889 XXXSDEPKFGCTSG----RQCSSDQFKC-GNGRCILNNWLCDGENDCGDGSDESSERGCK 4053
DE GC SG +CS ++ C +GRCI +CDG DC DE++
Sbjct: 248 KDNGDED--GCESGPHDVHKCSPREWSCPESGRCISIYKVCDGILDCPGREDENN----- 300
Query: 4054 TSMNARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCSFK 4233
T G C+ LCSA C ++
Sbjct: 301 --------------------------------------TSTGKYCSMTLCSA--LNCQYQ 320
Query: 4234 CHNSPNGPICSCPFGEQLVN---KTKCEPENECLDSSSCSQRCKDEKHGFTCSCDEGYEL 4404
CH +P G C CP G ++N C ++C C Q+C+ C C+EGY L
Sbjct: 321 CHETPYGGACFCPPG-YIINHNDSRTCVEFDDCQIWGICDQKCESRPGRHLCHCEEGYIL 379
Query: 4405 DVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGAIVEN-----AIALAWDSLT 4569
+ + CK D+ + I SN + D + +F +VE+ A+ +A+
Sbjct: 380 E-RGQYCKANDSFGEASIIFSNGRDLLIGD---IHGRSFRILVESQNRGVAVGVAFHYHL 435
Query: 4570 DRIYWSDIREKKILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVDSSLNTIEVAN 4749
R++W+D + K+ S + NG N + ++ E +A+DWV +Y V++ +N I++ N
Sbjct: 436 QRVFWTDTVQNKVFSVDINGLNIQEVLNVSVETPENLAVDWVNNKIYLVETKVNRIDMVN 495
Query: 4750 LEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDW---GQNPCIERASMDGTDRQIIVKT 4920
L D R L+ +N+ PRGIAVDP G +F++DW P +ERA MDG++R+ +VKT
Sbjct: 496 L-DGSYRVTLITENLGHPRGIAVDPTVGYLFFSDWESLSGEPKLERAFMDGSNRKDLVKT 554
Query: 4921 KIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFEDMM 5100
K+ WP + LD + RVY+ DS+ D+I+ V YDG R V+ + HP +++FE +
Sbjct: 555 KLGWPAGVTLDMISKRVYWVDSRFDYIETVTYDGIQRKTVVHGGSLIPHPFGVSLFEGQV 614
Query: 5101 YYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTN--PCSH 5274
+++D + K+ Y + + GV H + QP NPC N C
Sbjct: 615 FFTDWTKMAVLKANKFTETNPQVYYQASL-RPYGVTVYHSLRQP-YATNPCKDNNGGCEQ 672
Query: 5275 LCLLNNKNT-----FTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNVFGIEMNSASEKE 5439
+C+L+++ F CKC G +LD + CI + FL+ + + GI +++++
Sbjct: 673 VCVLSHRTDNDGLGFRCKCTFGFQLDTDERHCI-AVQNFLIFSSQVAIRGIPFTLSTQED 731
Query: 5440 TPVLAGMVPLSGLGNAF-DAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNGGNK 5616
MVP+SG + F +DA +F + + H I++ ++G +
Sbjct: 732 V-----MVPVSGNPSFFVGIDFDAQDSTIFFSDMSKH-----------MIFKQKIDGTGR 775
Query: 5617 TKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVI--LSNDQSXXXX 5790
+ ++ V ++ L FDW +NL + ++I ++R K R+V+ L+N +S
Sbjct: 776 EILAANRV-ENVESLAFDWISKNLYWTDSHYKSISVMRLADKTRRTVVQYLNNPRSVVVH 834
Query: 5791 XXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAIDTTNT 5970
GY+F+ D AK+ RA DGS+ L + + L + +AID +
Sbjct: 835 PFA---------GYLFFTD---WFRPAKIMRAWSDGSHLLPVINTTLGWPNGLAIDWAAS 882
Query: 5971 RVYFSEAKAGRISSVTYDGQDRHYV-LSDGGRQPNGLAFYGDRLFYADSAFDS-IEVATI 6144
R+Y+ +A +I T+DG DR + + P GLA +G+ LF+ D + I V
Sbjct: 883 RLYWVDAYFDKIEHSTFDGLDRRRLGHIEQMTHPFGLAIFGEHLFFTDWRLGAIIRVRKA 942
Query: 6145 NGDSQPPQWTHFKKDVENLANIKA----LQPRASSSGHPCHINNGNCDHICIPLMFAQRT 6312
+G + T + + + ++K+ +Q +++ P H NG+C H C P+ QR
Sbjct: 943 DGG----EMTVIRSGIAYILHLKSYDVNIQTGSNACNQPTH-PNGDCSHFCFPVPNFQRV 997
Query: 6313 CTCANG 6330
C C G
Sbjct: 998 CGCPYG 1003
Score = 336 bits (862), Expect = 9e-90
Identities = 210/713 (29%), Positives = 326/713 (45%), Gaps = 48/713 (6%)
Frame = +1
Query: 8875 QQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNL- 9051
Q+C + RC SG CIP W+CDG DCSD DE C C Y F+C +
Sbjct: 26 QECDSAHFRCGSGHCIPADWRCDGTKDCSDDADE--IGCAVVT----CQQGY-FKCQSEG 78
Query: 9052 KCISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCD 9231
+CI +++ R C TC+ + C++ +CIP + CD
Sbjct: 79 QCIPSSWV--CDQDQDCDDGSDERQDCSQSTCSSHQITCSNG--------QCIPSEYRCD 128
Query: 9232 GDVTCAGGEDES-------------TELCKTEKKECN-------------------KGEF 9315
C G DE+ C ++C+ EF
Sbjct: 129 HVRDCPDGADENDCQYPTCEQLTCDNGACYNTSQKCDWKVDCRDSSDEINCTEICLHNEF 188
Query: 9316 RCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCANHKCVPNSWKCDGNDDC 9495
C N CI + CD DNDC DGSDEHA C Y +C F C + +C+ +W CDG DDC
Sbjct: 189 SCGNGECIPRAYVCDHDNDCQDGSDEHA-CNYPTCGGYQFTCPSGRCIYQNWVCDGEDDC 247
Query: 9496 EDGSDEKDCPKNSASAQKASKCSNGQFQC-TSGECIDDAKVCDRNFDCTDRSDESSLCFI 9672
+D DE C + KCS ++ C SG CI KVCD DC R DE++
Sbjct: 248 KDNGDEDGC---ESGPHDVHKCSPREWSCPESGRCISIYKVCDGILDCPGREDENNTSTG 304
Query: 9673 DECS--LAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNEC-YEGISGCSQKC 9843
CS L C+ +C + G C C G+ I+ +D ++C ++C GI C QKC
Sbjct: 305 KYCSMTLCSALNCQYQCHETPYGGACFCPPGYIINHNDSRTCVEFDDCQIWGI--CDQKC 362
Query: 9844 DDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYELAAQGF 10023
+ + G + C C +GY L + CK + E + +N + I G + + +
Sbjct: 363 ESRPGRHLCHCEEGYILERGQY-CKANDSFGEASIIFSNGRDLLIGDIHGRSFRILVESQ 421
Query: 10024 DNVVSLDIDLTE--KKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDW 10197
+ V++ + ++ + D + ++ VD++ + + + VL +V E +AVDW
Sbjct: 422 NRGVAVGVAFHYHLQRVFWTDTVQNKVFSVDINGL-----NIQEVLNVSVETPENLAVDW 476
Query: 10198 VGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFFTEW---SLQP 10368
V K+Y++ + I + LDG + TLI + + P+ I V P GYLFF++W S +P
Sbjct: 477 VNNKIYLVETKVNRIDMVNLDGSYRVTLITENLGHPRGIAVDPTVGYLFFSDWESLSGEP 536
Query: 10369 YIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGR 10548
+ R +DGS L + LGWP + +D S R++W D+ + I + +DG R
Sbjct: 537 KLERAFMDGSNRKD-----LVKTKLGWPAGVTLDMISKRVYWVDSRFDYIETVTYDGIQR 591
Query: 10549 RHI--PAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDLRIV 10722
+ + H + +F+ +++ DW VL+ +K+T N + + P + +
Sbjct: 592 KTVVHGGSLIPHPFGVSLFEGQVFFTDWTKMAVLKANKFTETNPQVYYQASLRPYGVTVY 651
Query: 10723 HPMRQPAYPNPCGDNNGGCSHLCLIG----AGGNGYTCSCPDQFVLLSDQKTC 10869
H +RQP NPC DNNGGC +C++ G G+ C C F L +D++ C
Sbjct: 652 HSLRQPYATNPCKDNNGGCEQVCVLSHRTDNDGLGFRCKCTFGFQLDTDERHC 704
Score = 241 bits (614), Expect = 5e-61
Identities = 218/773 (28%), Positives = 313/773 (40%), Gaps = 109/773 (14%)
Frame = +1
Query: 133 SVNTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTW 312
S + AS C FRC +G+CI W P C S CD +T
Sbjct: 3627 SSHCASRTCRPGQFRCANGRCIPQAW---KCDVDNDCGDHSDEPIEECMSSAHLCDNFTE 3683
Query: 313 HSVS----CIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCD 480
S CI ++ C+ + DC D SDE+ C T C F C + C + +CD
Sbjct: 3684 FSCKTNYRCIPKWAVCNGVDDCRDNSDEQGCEERT--CHPVGDFRCKN-HHCIPLRWQCD 3740
Query: 481 GKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEF 660
G+ DC D SDE++ R C + +FRC ++ QCI W+CD DC D SDE D CE
Sbjct: 3741 GQNDCGDNSDEENCAPRE---CTESEFRCVNQ-QCIPSRWICDHYNDCGDNSDERD-CEM 3795
Query: 661 KKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGT-----GH- 822
+ C FQC + C + +CD DC D SDE +C R P G + C T H
Sbjct: 3796 RTCHPEYFQCTSGHCVHSELKCDGSADCLDASDEADC-PTRFPDGAY-CQATMFECKNHV 3853
Query: 823 CIDQLKLCDGSKDCADGADEQ---------------QCSQNLCPSL--------GCQAGC 933
CI CDG DC DG+DE+ +C N C C G
Sbjct: 3854 CIPPYWKCDGDDDCGDGSDEELHLCLDVPCNSPNRFRCDNNRCIYSHEVCNGVDDCGDGT 3913
Query: 934 HPS------PHGGECT-----CPSGYKLDDRFHRTCSDINECAEF--------------- 1035
+ P CT C +G+ + C D ++C ++
Sbjct: 3914 DETEEHCRKPTPKPCTEYEYKCGNGHCIP--HDNVCDDADDCGDWSDELGCNKGKERTCA 3971
Query: 1036 -GYCDQLCAN-HRPGFTCSCLG----------DCFTL----QMEHGPGKDNLTMRGY-CV 1164
C+Q C + GF CSC C + Q P T Y CV
Sbjct: 3972 ENICEQNCTQLNEGGFICSCTAGFETNVFDRTSCLDINECEQFGTCPQHCRNTKGSYECV 4031
Query: 1165 -----SNNADKM-KLFVARREGLYRLNPKNPDEEVKKLASGEF---------IYGIDFDY 1299
++ +D+ K A L P N L+S F I +D+D+
Sbjct: 4032 CADGFTSMSDRPGKRCAAEGSSPLLLLPDNVRIRKYNLSSERFSEYLQDEEYIQAVDYDW 4091
Query: 1300 -----GDRKIFWTDRLAHSAFSA--------DVDDEGEISQIKKLSLKSLVYPRCLAVDW 1440
G +++T R S F A + Q L LK ++ P +AVDW
Sbjct: 4092 DPEDIGLSVVYYTVRGEGSRFGAIKRAYIPNFESGRNNLVQEVDLKLKYVMQPDGIAVDW 4151
Query: 1441 ITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTN---QLKLE 1611
+ +Y + ++RI+V+ DG R L++ L P IA++P G MF+T+ + KLE
Sbjct: 4152 VGRHIYWSDVKNKRIEVAKLDGRYRKWLISTDLDQPAAIAVNPKLGLMFWTDWGKEPKLE 4211
Query: 1612 AAAMDGTNRRTLVNTHTHQVSGIVVD-ITAKRVYWVDPKVDRLESIDYQGNDRRIVA-QG 1785
+A M+G +R LV +G+ +D + R+YW D K D +E+I Y G DRR++A +
Sbjct: 4212 SAWMNGEDRNILVFEDLGWPTGLSIDYLNNDRIYWSDFKEDVIETIKYDGTDRRVIAKEA 4271
Query: 1786 MNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMA 1965
MN P+ L +F+ LYW + V + KFG K N + + +H +
Sbjct: 4272 MN----PYSLDIFEDQLYWISKEKGEVWKQNKFGQGKK--EKTLVVNPWLTQVRIFHQLR 4325
Query: 1966 QPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNG 2124
+ N C C +C+L GY CACP G + G
Sbjct: 4326 ---------YNKSVPNLCKQI-CSHLCLLRPG------GYSCACPQGSSFIEG 4362
Score = 239 bits (609), Expect = 2e-60
Identities = 187/684 (27%), Positives = 283/684 (41%), Gaps = 27/684 (3%)
Frame = +1
Query: 130 ASVNTASSVCNENDFRCNDGKCIRTEW---XXXXXXXXXXXXXXXXXPHPGCKSDQWQCD 300
AS + C ++F+C+ G+CI +EW + C ++ C
Sbjct: 2897 ASCGHSERTCLADEFKCDGGRCIPSEWICDGDNDCGDMSDEDKRHQCQNQNCSDSEFLCV 2956
Query: 301 TYTWHSVSCIAEYQRCDNITDCADGSDE-KDCPASTVDCSSQNVFMCADGRQCFDVSKKC 477
CI + CD DC DG DE ++C T S+N F C G C +C
Sbjct: 2957 NDRPPDRRCIPQSWVCDGDVDCTDGYDENQNCTRRT---CSENEFTCGYG-LCIPKIFRC 3012
Query: 478 DGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDE-PDTC 654
D DC D SDE+ + C Q QF C +CI K++VCD DC DGSDE C
Sbjct: 3013 DRHNDCGDYSDERGCL---YQTCQQNQFTC-QNGRCISKTFVCDEDNDCGDGSDELMHLC 3068
Query: 655 EFKK--CTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCI 828
+ C +EF+C N RC C++ DDC DNSDE C
Sbjct: 3069 HTPEPTCPPHEFKCDNGRCIEMMKLCNHLDDCLDNSDEKGC------------------- 3109
Query: 829 DQLKLCDGSKDCADGADEQQCSQNLCPSL-GCQAGCHPSPHGGECTCPSGYKL-DDRFHR 1002
G +C D PS+ GC C + C+C GYKL D+ R
Sbjct: 3110 -------GINECHD------------PSISGCDHNCTDTLTSFYCSCRPGYKLMSDK--R 3148
Query: 1003 TCSDINECAEFGY-CDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNAD 1179
TC DI+EC E + C Q C N + C C + + + + N + Y + +N
Sbjct: 3149 TCVDIDECTEMPFVCSQKCENVIGSYICKC-APGYLREPDGKTCRQNSNIEPYLIFSNRY 3207
Query: 1180 KMKLFVARREG-LYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTD---RLAHSAF 1347
++ +G Y L + D + +DFD +++++W D ++ F
Sbjct: 3208 YLRNLTI--DGYFYSLILEGLDN----------VVALDFDRVEKRLYWIDTQRQVIERMF 3255
Query: 1348 SADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLL 1527
+ E I+ L LAVDW++ LY +++ + VS +G R +L
Sbjct: 3256 LNKTNKETIINH-------RLPAAESLAVDWVSRKLYWLDARLDGLFVSDLNGGHRRMLA 3308
Query: 1528 ADGLTL--------PLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVS 1674
+ P +AL P G +++ ++ + MDGTN+ +++T +
Sbjct: 3309 QHCVDANNTFCFDNPRGLALHPQYGYLYWADWGHRAYIGRVGMDGTNKSVIISTKLEWPN 3368
Query: 1675 GIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWT 1854
GI +D T +YW D + +E D +G+ R V G +PHPF + +F+ +YWTDW
Sbjct: 3369 GITIDYTNDLLYWADAHLGYIEYSDLEGHHRHTVYDG--ALPHPFAITIFEDTIYWTDWN 3426
Query: 1855 RLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPC--TNA 2028
V + K+ + NT + P I YHP QP + NPC N
Sbjct: 3427 TRTVEKGNKYDGSNRQTLVNTTHR--PFDIHVYHPYRQP----------IVSNPCGTNNG 3474
Query: 2029 DCEGMCILSKDNGGFGVGYKCACP 2100
C +C++ G G+ C CP
Sbjct: 3475 GCSHLCLIKPG----GKGFTCECP 3494
Score = 222 bits (565), Expect = 2e-55
Identities = 196/737 (26%), Positives = 297/737 (39%), Gaps = 60/737 (8%)
Frame = +1
Query: 11503 DVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRC-NDGKCIPG 11679
D FRC SG CIP W CD DC D++DE+ C T C + F+C ++G+CIP
Sbjct: 29 DSAHFRCG-SGHCIPADWRCDGTKDCSDDADEI--GCAVVT--CQQGYFKCQSEGQCIPS 83
Query: 11680 SKVCDGTIQCSDGLDESQ-------------CTLRRCLPGHRQ----------------- 11769
S VCD C DG DE Q C+ +C+P +
Sbjct: 84 SWVCDQDQDCDDGSDERQDCSQSTCSSHQITCSNGQCIPSEYRCDHVRDCPDGADENDCQ 143
Query: 11770 --------CDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFECANSVCIPRK 11925
CD+G C + CD K DC +++DE++C ++ C EF C N CIPR
Sbjct: 144 YPTCEQLTCDNGACYNTSQKCDWKVDCRDSSDEINCTEI----CLHNEFSCGNGECIPRA 199
Query: 11926 FMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDE 12105
++ SDE + C C +F C R C+ +C+G +DC N D
Sbjct: 200 YVCDHDNDCQDGSDEHA--CNYPTCG-GYQFTCPSGR-CIYQNWVCDGEDDCKDNGDED- 254
Query: 12106 HLSMCSSFSEYGDCSSDQFKC-ANGKCVNGTVACDRKDDCGDASDEIGCS--KHGGKTSC 12276
S + CS ++ C +G+C++ CD DC DE S K+ T C
Sbjct: 255 --GCESGPHDVHKCSPREWSCPESGRCISIYKVCDGILDCPGREDENNTSTGKYCSMTLC 312
Query: 12277 EAFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGS 12456
A C++ C + G C C G+ + + C++ D+C C Q C + G
Sbjct: 313 SAL----NCQYQCHETPYGGACFCPPGYIINHNDSRTCVEFDDCQIWGICDQKCESRPGR 368
Query: 12457 YLCRCHEDYENNVVVGSMTGKDCRAK---GDAANVMIGADDSLVQLSLHGSGTNRHXXXX 12627
+LC C E Y G+ C+A G+A+ + D L+ +HG
Sbjct: 369 HLCHCEEGYILE------RGQYCKANDSFGEASIIFSNGRDLLIG-DIHGRSFRILVESQ 421
Query: 12628 XXXXXXXXXXXXXXPRKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTA 12807
R ++W D + ++ S NG E + V+ P
Sbjct: 422 NRGVAVGVAFHYHLQR---VFWTDTVQNKVF-SVDINGLNIQEVLNVSVE------TPEN 471
Query: 12808 IAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGH 12987
+AVD+ +++ N ID N DG Y ++ +
Sbjct: 472 LAVDWVNNKIYLVETKVN---------------RIDMVNL--------DGSYRVTLITEN 508
Query: 12988 LQQPTALITAPSAGRICYSD---AGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGK 13158
L P + P+ G + +SD K+E A MDG++R+ +VK + P + +D
Sbjct: 509 LGHPRGIAVDPTVGYLFFSDWESLSGEPKLERAFMDGSNRKDLVKTKLGWPAGVTLDM-I 567
Query: 13159 GNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHI---PYAVDVFENHIYWLSRESKTLYVQ 13329
R+YWVD ++ ++ V DG +R TVVH + P+ V +FE +++ +
Sbjct: 568 SKRVYWVDSRFDYIETVTYDGIQRKTVVHGGSLIPHPFGVSLFEGQVFFTDWTKMAVLKA 627
Query: 13330 DKFGRGRVSVL--ASDLEDGHTV--RVSQKYAKDTQRTVSGCERAQCSHLCVSLPST--- 13488
+KF V AS G TV + Q YA + + +G C +CV T
Sbjct: 628 NKFTETNPQVYYQASLRPYGVTVYHSLRQPYATNPCKDNNG----GCEQVCVLSHRTDND 683
Query: 13489 --GFACLCPDGIVPQLD 13533
GF C C G QLD
Sbjct: 684 GLGFRCKCTFGF--QLD 698
Score = 140 bits (353), Expect = 9e-31
Identities = 101/332 (30%), Positives = 129/332 (38%), Gaps = 10/332 (3%)
Frame = +1
Query: 10879 CTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRP 11058
C F CG CIP W CDG DC D +DE G C C G F
Sbjct: 28 CDSAHFRCGS--GHCIPADWRCDGTKDCSDDADEIG---CAVVTCQQGYF---------- 72
Query: 11059 FQIXXXXXXXXXXXXEQNCDKACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEADTLC 11238
KC + G+CIP + SDE
Sbjct: 73 ----------------------------KCQSEGQCIPSSWVCDQDQDCDDGSDERQDCS 104
Query: 11239 MSAERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXET----PECAQIECKKGWTRCSS 11406
S C++ + C+N +CI +R E P C Q+ C G
Sbjct: 105 QS---TCSSHQITCSNGQCIPSEYRCDHVRDCPDGADENDCQYPTCEQLTCDNG------ 155
Query: 11407 SYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMCDTENDCGD 11586
C C+ + DCRD+SDE C EF C +G+CIPR ++CD +NDC D
Sbjct: 156 --ACYNTSQKCDWKVDCRDSSDE--INCTEICLHNEFSCG-NGECIPRAYVCDHDNDCQD 210
Query: 11587 NSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQC-----TLRRC 11751
SDE +C T C +F C G+CI + VCDG C D DE C + +C
Sbjct: 211 GSDE--HACNYPT--CGGYQFTCPSGRCIYQNWVCDGEDDCKDNGDEDGCESGPHDVHKC 266
Query: 11752 LPGHRQC-DDGTCIAEHKWCDRKKDCPNAADE 11844
P C + G CI+ +K CD DCP DE
Sbjct: 267 SPREWSCPESGRCISIYKVCDGILDCPGREDE 298
Score = 139 bits (351), Expect = 2e-30
Identities = 115/414 (27%), Positives = 164/414 (38%), Gaps = 19/414 (4%)
Frame = +1
Query: 8389 NFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNR-RCIDSAKKCNH 8565
+F+CG G CI CD DC+D +DE C +C + Y C + +CI S+ C+
Sbjct: 32 HFRCGSGHCIPADWRCDGTKDCSDDADEIG--CAVVTCQQGYFKCQSEGQCIPSSWVCDQ 89
Query: 8566 IDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHD-EQVSDESLATCPG 8742
DC DGSDE S C+ CSNG CI CD DC D +D TC
Sbjct: 90 DQDCDDGSDERQDCSQSTCSSHQITCSNGQCIPSEYRCDHVRDCPDGADENDCQYPTCEQ 149
Query: 8743 LPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCI 8922
L D C + CD DC D +DE + C + C + C +G CI
Sbjct: 150 LTCD----------NGACYNTSQKCDWKVDCRDSSDE--INC-TEICLHNEFSCGNGECI 196
Query: 8923 PETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXX 9102
P + CD DNDC DG DE N G Y F C + +CI + ++
Sbjct: 197 PRAYVCDHDNDCQDGSDEHACNYPTCGG-------YQFTCPSGRCIYQNWVCDGEDDCKD 249
Query: 9103 XXXXHSRHGCGN-----RTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDES 9267
GC + C+ +E+ C + + CI +CDG + C G EDE+
Sbjct: 250 NG---DEDGCESGPHDVHKCSPREWSCPESGR-------CISIYKVCDGILDCPGREDEN 299
Query: 9268 TELCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDC-------LDGSDEHANCTYSSCQP 9426
+ K C+ CS +C + E C ++ +D + CQ
Sbjct: 300 N---TSTGKYCSM--TLCSALNCQYQCHETPYGGACFCPPGYIINHNDSRTCVEFDDCQ- 353
Query: 9427 DFFQCANHKCV--PNSWKCDGNDDCEDG---SDEKDCPKNSASAQKASKCSNGQ 9573
+ + KC P C CE+G + C N + + + SNG+
Sbjct: 354 -IWGICDQKCESRPGRHLC----HCEEGYILERGQYCKANDSFGEASIIFSNGR 402
Score = 130 bits (327), Expect = 9e-28
Identities = 78/229 (34%), Positives = 110/229 (47%), Gaps = 15/229 (6%)
Frame = +1
Query: 9274 LCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCANH- 9450
L +EC+ FRC + HCI + W CDG DC D +DE C +CQ +F+C +
Sbjct: 20 LAPASGQECDSAHFRCGSGHCIPADWRCDGTKDCSDDADE-IGCAVVTCQQGYFKCQSEG 78
Query: 9451 KCVPNSWKCDGNDDCEDGSDEK-DCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRN 9627
+C+P+SW CD + DC+DGSDE+ DC + S CS+ Q C++G+CI CD
Sbjct: 79 QCIPSSWVCDQDQDCDDGSDERQDCSQ--------STCSSHQITCSNGQCIPSEYRCDHV 130
Query: 9628 FDCTDRSDESSLCFIDECSLAEKPLCEQKCMD--------MKIGYKCDCFEGFAIDISDQ 9783
DC D +DE+ + P CEQ D K +K DC D SD+
Sbjct: 131 RDCPDGADEND---------CQYPTCEQLTCDNGACYNTSQKCDWKVDC-----RDSSDE 176
Query: 9784 KSC-----HNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSC 9915
+C HN C G +C + +Y C + Q SD+H+C
Sbjct: 177 INCTEICLHNEFSCGNG------ECIPR--AYVCDHDNDCQDGSDEHAC 217
Score = 90.1 bits (222), Expect = 1e-15
Identities = 81/286 (28%), Positives = 113/286 (39%), Gaps = 10/286 (3%)
Frame = +1
Query: 11743 RRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFEC-ANSVCIP 11919
+ C H +C G CI CD KDC + ADE+ C V TC F+C + CIP
Sbjct: 26 QECDSAHFRCGSGHCIPADWRCDGTKDCSDDADEIGCAVV---TCQQGYFKCQSEGQCIP 82
Query: 11920 RKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFS 12099
++ SDE +C + C +H C N C P+++
Sbjct: 83 SSWVCDQDQDCDDGSDE-RQDCSQSTCS-------SHQITCSN--------GQCIPSEYR 126
Query: 12100 DEHLSMCSSFSEYGDC---SSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSK--HGG 12264
+H+ C ++ DC + +Q C NG C N + CD K DC D+SDEI C++
Sbjct: 127 CDHVRDCPDGADENDCQYPTCEQLTCDNGACYNTSQKCDWKVDCRDSSDEINCTEICLHN 186
Query: 12265 KTSCEAFGNNGGC---KHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNN-TCTQ 12432
+ SC NG C ++C D C+DG S + + C G TC
Sbjct: 187 EFSC----GNGECIPRAYVCDHDND-----CQDG------SDEHACNYPTCGGYQFTCPS 231
Query: 12433 LCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADD 12570
RC Y+N V G DC+ GD G D
Sbjct: 232 ----------GRC--IYQNWVCDGE---DDCKDNGDEDGCESGPHD 262
Score = 84.7 bits (208), Expect = 6e-14
Identities = 55/181 (30%), Positives = 86/181 (47%), Gaps = 25/181 (13%)
Frame = +1
Query: 3925 SGRQCSSDQFKCGNGRCILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACEN 4104
SG++C S F+CG+G CI +W CDG DC SD++ E GC C + C++
Sbjct: 24 SGQECDSAHFRCGSGHCIPADWRCDGTKDC---SDDADEIGCAVV----TCQQGYFKCQS 76
Query: 4105 DQETCIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCS--------FKC---HNSPN 4251
+ + CIP +CD C G+DE C++ CS+ + CS ++C + P+
Sbjct: 77 EGQ-CIPSSWVCDQDQDCDDGSDERQDCSQSTCSSHQITCSNGQCIPSEYRCDHVRDCPD 135
Query: 4252 G--------PIC---SCPFGEQLVNKTKCEPENECLDSS---SCSQRCKDEKHGFTCSCD 4389
G P C +C G KC+ + +C DSS +C++ C + F+C
Sbjct: 136 GADENDCQYPTCEQLTCDNGACYNTSQKCDWKVDCRDSSDEINCTEICLHNE--FSCGNG 193
Query: 4390 E 4392
E
Sbjct: 194 E 194
Score = 46.6 bits (109), Expect = 0.018
Identities = 26/86 (30%), Positives = 38/86 (43%), Gaps = 3/86 (3%)
Frame = +1
Query: 12109 LSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSK---HGGKTSCE 12279
L C + + +C S F+C +G C+ CD DC D +DEIGC+ G C+
Sbjct: 16 LVACLAPASGQECDSAHFRCGSGHCIPADWRCDGTKDCSDDADEIGCAVVTCQQGYFKCQ 75
Query: 12280 AFGNNGGCKHICTDVRDGFYCHCRDG 12357
+ G +C +D C DG
Sbjct: 76 SEGQCIPSSWVCDQDQD-----CDDG 96
>gi|32816595|gb|AAP88585.1| glycoprotein receptor gp330/megalin
precursor [Homo sapiens]
Length = 4655
Score = 2532 bits (6562), Expect = 0.0
Identities = 1522/4609 (33%), Positives = 2304/4609 (49%), Gaps = 100/4609 (2%)
Frame = +1
Query: 136 VNTASSVCNENDFRC-NDGKCIRTEWXXXXXXXXXXXXXXXXX-PHPGCKSDQWQCDTYT 309
+ A C + F+C ++G+CI + W C S Q C
Sbjct: 60 IGCAVVTCQQGYFKCQSEGQCIPSSWVCDQDQDCDDGSDERQDCSQSTCSSHQITCS--- 116
Query: 310 WHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKY 489
+ CI RCD++ DC DG+DE DC T + + D C++ S+KCD K
Sbjct: 117 --NGQCIPSEYRCDHVRDCPDGADENDCQYPTCEQ------LTCDNGACYNTSQKCDWKV 168
Query: 490 DCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKC 669
DCRD SDE + C+ C +F C + +CI +++VCD DC DGSDE C + C
Sbjct: 169 DCRDSSDEIN-CTE---ICLHNEFSCGNG-ECIPRAYVCDHDNDCQDGSDE-HACNYPTC 222
Query: 670 TANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGE-----YRCPPGKWNCPGTGHCIDQ 834
+F C + RC + + CD DDC DN DED C ++C P +W+CP +G CI
Sbjct: 223 GGYQFTCPSGRCIYQNWVCDGEDDCKDNGDEDGCESGPHDVHKCSPREWSCPESGRCISI 282
Query: 835 LKLCDGSKDCADGADEQQ------CSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRF 996
K+CDG DC DE CS LC +L CQ CH +P+GG C CP GY ++
Sbjct: 283 YKVCDGILDCPGREDENNTSTGKYCSMTLCSALNCQYQCHETPYGGACFCPPGYIINHND 342
Query: 997 HRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNA 1176
RTC + ++C +G CDQ C + C C + ++ D+ SN
Sbjct: 343 SRTCVEFDDCQIWGICDQKCESRPGRHLCHCEEGYILERGQYCKANDSFGEASIIFSNGR 402
Query: 1177 DKMKLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSAD 1356
D + + R + +N V G+ F Y +++FWTD + + FS D
Sbjct: 403 DLLIGDIHGRSFRILVESQNRGVAV----------GVAFHYHLQRVFWTDTVQNKVFSVD 452
Query: 1357 VDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADG 1536
++ I ++ +S+++ P LAVDW+ N +Y++E+ RID+ + DG R L+ +
Sbjct: 453 INGLN-IQEVLNVSVET---PENLAVDWVNNKIYLVETKVNRIDMVNLDGSYRVTLITEN 508
Query: 1537 LTLPLDIALDPLRGEMFFTN------QLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITA 1698
L P IA+DP G +FF++ + KLE A MDG+NR+ LV T +G+ +D+ +
Sbjct: 509 LGHPRGIAVDPTVGYLFFSDWESLSGEPKLERAFMDGSNRKDLVKTKLGWPAGVTLDMIS 568
Query: 1699 KRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVE 1878
KRVYWVD + D +E++ Y G R+ V G +++PHPFG++LF+ +++TDWT++ V++
Sbjct: 569 KRVYWVDSRFDYIETVTYDGIQRKTVVHGGSLIPHPFGVSLFEGQVFFTDWTKMAVLKAN 628
Query: 1879 KFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPC--TNADCEGMCIL 2052
KF ++ ++ P G++ YH + QP NPC N CE +C+L
Sbjct: 629 KFTETNPQVYYQA--SLRPYGVTVYHSLRQP----------YATNPCKDNNGGCEQVCVL 676
Query: 2053 SKDNGGFGVGYKCACPIGQKLVNGKR-CIDSIDYLLFSSNKIVRGIFPEINEKALAEAVL 2229
S G+G++C C G +L +R CI ++L+FSS +RGI ++ + + ++
Sbjct: 677 SHRTDNDGLGFRCKCTFGFQLDTDERHCIAVQNFLIFSSQVAIRGIPFTLSTQE--DVMV 734
Query: 2230 PISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMS 2409
P+S +G+ F D ++ F++D+ + I++ + DG G + + + S++
Sbjct: 735 PVSGNPSFFVGIDF----DAQDSTIFFSDMSKHMIFKQKIDGTGREILAANRVENVESLA 790
Query: 2410 FDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKGLLFY 2589
FDWISK LY+ D+ S+ V+++ + RR ++ L +P SVVVHP+ G LF+
Sbjct: 791 FDWISKNLYWTDSHYKSISVMRLADK--------TRRTVVQYLNNPRSVVVHPFAGYLFF 842
Query: 2590 AEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGK 2769
+ RPA I R DG + + NTTLG P+ +AID+A +RL W D I FDG
Sbjct: 843 TDWFRPAKIMRAWSDGSHLLPVINTTLGWPNGLAIDWAASRLYWVDAYFDKIEHSTFDGL 902
Query: 2770 NVVKLDIDNPI--PVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFS 2943
+ +L + P + I E++++ R +I RV K +GG ++R A I
Sbjct: 903 DRRRLGHIEQMTHPFGLAIFGEHLFFTDWRLGAIIRVRKADGGEMTVIRSGIA---YILH 959
Query: 2944 LKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINKENNHS 3123
LK+ Q + + C+ CF P+ + C C G + N+ +
Sbjct: 960 LKSYDVNIQTGSNACNQPTHPNGDCSHFCFPVPN------FQRVCGCPYGMRL-ASNHLT 1012
Query: 3124 CQKDPA-EKIEQLCSSNSTQFQCKNGRCIPKEWKCDGENDCLDESDEIDEKGDKCFH-ET 3297
C+ DP E + C S F CKNGRC+P + CDG +DC D SDE C
Sbjct: 1013 CEGDPTNEPPTEQCGLFS--FPCKNGRCVPNYYLCDGVDDCHDNSDE-----QLCGTLNN 1065
Query: 3298 ECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNHRCI 3477
C+ + C + + CIPA C C ++ CDNH+CI
Sbjct: 1066 TCSSSAFTCGHGE-CIPAHWRCDKRNDCVDGSDEH--NCPTHAPASCLDTQYTCDNHQCI 1122
Query: 3478 PEQWKXXXXXXXXXXXXEKLEMCGNA-TCAANQFSCANGRCIPIYWLCDGDNDCYDGTDE 3654
+ W EK C + TC +QF+C N RCI + ++CDGD DC DG+DE
Sbjct: 1123 SKNWVCDTDNDCGDGSDEK--NCNSTETCQPSQFNCPNHRCIDLSFVCDGDKDCVDGSDE 1180
Query: 3655 DKERCPPVQCSALQFRCANGRQCVPLRNHXXXXXXXXXXXXXXXXAVTAES-CTPDQFKC 3831
C + C+A QF+CA+G +C+ + N C D+F+C
Sbjct: 1181 --VGCV-LNCTASQFKCASGDKCIGVTNRCDGVFDCSDNSDEAGCPTRPPGMCHSDEFQC 1237
Query: 3832 VSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKCGNGRCILNNWLCDGEND 4011
G+CIP W+ SDE C + C S F C NG CI WLCD +ND
Sbjct: 1238 QEDGICIPNFWECDGHPDCLYGSDEHN-ACVP-KTCPSSYFHCDNGNCIHRXWLCDRDND 1295
Query: 4012 CGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGGRCA 4191
CGD SDE + C T +CP C C+ L +CDG CP GTDE C
Sbjct: 1296 CGDMSDE---KDCPTQ--PFRCPSWQWQCLG-HNICVNLSVVCDGIFDCPNGTDESPLCN 1349
Query: 4192 RDLCSADRAGCSFKCHNSPNGPICSCPFGEQLVNKTK-CEPENECLDSSSCSQRCKDEKH 4368
+ CS GC+ +C P G C CP G L N +K CE +EC SCSQ C + +
Sbjct: 1350 GNSCSDFNGGCTHECVQEPFGAKCLCPLGFLLANDSKTCEDIDECDILGSCSQHCYNMRG 1409
Query: 4369 GFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGAIVENA-- 4542
F CSCD GY L+ D RTCKV + + + V+++N+I +D H ++VEN
Sbjct: 1410 SFRCSCDTGYMLESDGRTCKVTAS-ESLLLLVASQNKII-ADSVTSQVHNIYSLVENGSY 1467
Query: 4543 -IALAWDSLTDRIYWSDIREKKILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVD 4719
+A+ +DS++ RI+WSD + K SA +NGT+ V + +TE IA+DWVGRNLYW D
Sbjct: 1468 IVAVDFDSISGRIFWSDATQGKTWSAFQNGTDRRVVFDSSIILTETIAIDWVGRNLYWTD 1527
Query: 4720 SSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKG--VMFWTDWGQNPCIERASMDG 4893
+L TIEV+ + D RT+L+ +N++ PRG+A+DPR ++FW+DWG +P IERASMDG
Sbjct: 1528 YALETIEVSKI-DGSHRTVLISKNLTNPRGLALDPRMNEHLLFWSDWGHHPRIERASMDG 1586
Query: 4894 TDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPH 5073
+ R +IV+ KI+WP + +DY +YF DS LD++DF +Y+G R QV+AS ++HP+
Sbjct: 1587 SMRTVIVQDKIFWPCGLTIDYPNRLLYFMDSYLDYMDFCDYNGHHRRQVIASDLIIRHPY 1646
Query: 5074 ALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPC 5253
AL +FED +Y++DR +++ K+ G S + LG+VAVHP QP NPC
Sbjct: 1647 ALTLFEDSVYWTDRATRRVMRANKWHGGNQSVV-MYNIQWPLGIVAVHPSKQPN-SVNPC 1704
Query: 5254 STNPCSHLCLLNNKNT--FTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNVFGIEMNSA 5427
+ + CSHLCLL+++ ++C CP G L C+ D +PFL+ +++ +FGI +N
Sbjct: 1705 AFSRCSHLCLLSSQGPHFYSCVCPSGWSLSPDLLNCLRDDQPFLITVRQHIIFGISLNPE 1764
Query: 5428 SEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNG 5607
+ MVP++G+ N D +D + ++ +E+ I+R +G
Sbjct: 1765 VKSND----AMVPIAGIQNGLDVEFDDAEQYIYWVENPGE------------IHRVKTDG 1808
Query: 5608 GNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGK-QYRSVILSNDQSXX 5784
N+T S ++ + L DW RNL N TQ+IE++ G +YR +++ND +
Sbjct: 1809 TNRTVFASISMVGPSMNLALDWISRNLYSTNPRTQSIEVLTLHGDIRYRKTLIANDGTAL 1868
Query: 5785 XXXXXXXXXXXXXKGYVFWLDRG-GGAADAKVARAGLDGSNPLVIASNDLAELDHIAIDT 5961
+G ++W D+G AK+A A +DG++ + + +L L+ + +D
Sbjct: 1869 GVGFPIGITVDPARGKLYWSDQGTDSGVPAKIASANMDGTSVKTLFTGNLEHLECVTLDI 1928
Query: 5962 TNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAFDSIE-VA 6138
++Y++ G I DG DR +L P G+A + L+Y D ++ IE V
Sbjct: 1929 EEQKLYWAVTGRGVIERGNVDGTDR-MILVHQLSHPWGIAVHDSFLYYTDEQYEVIERVD 1987
Query: 6139 TINGDSQPPQWTHFKKDVENLANIKALQPR-ASSSGHPCHINNGNCDHICIPLMFAQRTC 6315
G ++ + +V NL ++ R A+ S + C N C IC+P+ +C
Sbjct: 1988 KATGANK----IVLRDNVPNLRGLQVYHRRNAAESSNGCSNNMNACQQICLPVPGGLFSC 2043
Query: 6316 TCANGY-VKDGQTSCKLFDESFVIVATKTKVIGYPIDETQSKGVAMEPIGGLSITG--VD 6486
CA G+ + SC ++ SF++V+ + + G+ + E M P+ G VD
Sbjct: 2044 ACATGFKLNPDNRSCSPYN-SFIVVSMLSAIRGFSL-ELSDHSETMVPVAGQGRNALHVD 2101
Query: 6487 YDYESKTIYVAEASGI---NKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINYNMYF 6657
D S IY + S + I SS ++ IG ++ +A+DW+ N+YF
Sbjct: 2102 VDVSSGFIYWCDFSSSVASDNAIRRIKPDGSSLMNIVTHGIGENGVRGIAVDWVAGNLYF 2161
Query: 6658 INHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQRSFLD 6837
N T IEV +++ TYR++LL + P I VDP +RYL+WAD GQ+P I+RSFLD
Sbjct: 2162 TNAFVSETLIEVLRINTTYRRVLLKVTVDMPRHIVVDPKNRYLFWADYGQRPKIERSFLD 2221
Query: 6838 GSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPELVR--SDIASAA 7011
+ R V+VS GI P L VD + +YW D +D I R+R G E++R S +
Sbjct: 2222 CTNRTVLVSEGIVTPRGLAVDRSDGYVYWVDDSLDIIARIRINGENSEVIRYGSRYPTPY 2281
Query: 7012 GVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRAS 7191
G+ + ++ W D L+K+F+A+ +P T PT + ++ + DV +F QPR
Sbjct: 2282 GITVFENSIIWVDRNLKKIFQASKEPENTE---PPTVIRDNINWLRDVTIFDKQVQPR-- 2336
Query: 7192 SPCQITDNL---RKSPCTQLCFATPGTQTPTCSCARGVLK--GRTCE-EPDTYIMFSDGD 7353
SP ++ +N C+ LCFA PG TP C CA G L+ G+ C + +++F+ +
Sbjct: 2337 SPAEVNNNPCLENNGGCSHLCFALPGLHTPKCDCAFGTLQSDGKNCAISTENFLIFALSN 2396
Query: 7354 KIIDVAIEPDVKASRPLKDPFPEIS---NLQTFDVDVNLRRVYFVVESPVGVN-ISWFSM 7521
+ + ++P+ + PF I+ + + D D R+YF GV IS+ ++
Sbjct: 2397 SLRSLHLDPENHSP-----PFQTINVERTVMSLDYDSVSDRIYFTQNLASGVGQISYATL 2451
Query: 7522 NNAENPRLVFGASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTIA 7701
++ + V A I + DW+T++IY++ + ++ G + + IA
Sbjct: 2452 SSGIHTPTVI-------ASGIGTADGIAFDWITRRIYYSDYLNQMINSMAEDGSNRTVIA 2504
Query: 7702 SGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIA 7881
A+ +DPC G L+W+D + T +IER+ L G R IV+ S+ +P+ +
Sbjct: 2505 RVPKPRAIVLDPCQGYLYWAD--WDTHA-----KIERATLGGNFRVPIVNSSLVMPSGLT 2557
Query: 7882 VDFRNQKIYWADVNRLNIEVADYDGQNRKVIASG-YRAKSLDIWDRWLYMSDPLSNGVFR 8058
+D+ +YW D + IE + G +R+VI + A L ++ +++Y +D + ++R
Sbjct: 2558 LDYEEDLLYWVDASLQRIERSTLTGVDREVIVNAAVHAFGLTLYGQYIYWTDLYTQRIYR 2617
Query: 8059 IDKESGSG----LENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQL 8226
+K GSG N++S R + V+ + Q CN C+ NGGC +
Sbjct: 2618 ANKYDGSGQIAMTTNLLSQPR--------GINTVVKNQKQQCN----NPCEQFNGGCSHI 2665
Query: 8227 CTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSEPAKECLPPYNFQCGD 8406
C G ++ QC + L C++ A +F C +
Sbjct: 2666 CAP-----GPNGAECQCPHEGNWYLANNR-----KHCIVDNGERCGAS------SFTCSN 2709
Query: 8407 GSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHIDDCGDG 8586
G CI CD+ DC D SDE + C +C C N RC+ + +C++ +DCGDG
Sbjct: 2710 GRCISEEWKCDNDNDCGDGSDEMESVCALHTCSPTAFTCANGRCVQYSYRCDYYNDCGDG 2769
Query: 8587 SDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPGLPIDCRGV 8766
SDE C A F C+N CI + +C+G ++CHD SDE CP C+
Sbjct: 2770 SDEAGCLFRDCNATTEFMCNNRRCIPREFICNGVDNCHDNNTSDEK--NCPDRT--CQSG 2825
Query: 8767 KVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCIPETWQCDG 8946
+C N+NICI LCDG +DCGD +DEN +C C+ +C SGRCIP+ W CD
Sbjct: 2826 YTKCHNSNICIPRVYLCDGDNDCGDNSDENPTYCTTHTCSSSEFQCTSGRCIPQHWYCDQ 2885
Query: 8947 DNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXXXXXXHSRH 9126
+ DC D DE +C + ++ C+ D F+CD +CI +I RH
Sbjct: 2886 ETDCFDASDEP-ASCGHS--ERTCLADE-FKCDGGRCIPSEWICDGDNDCGDMSDEDKRH 2941
Query: 9127 GCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECNK 9306
C N+ C+D EF C ++ P CIP++W+CDGDV C G DE+ + + C++
Sbjct: 2942 QCQNQNCSDSEFLCVNDRP---PDRRCIPQSWVCDGDVDCTDGYDENQNCTR---RTCSE 2995
Query: 9307 GEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCANHKCVPNSWKCDGN 9486
EF C CI + CD NDC D SDE C Y +CQ + F C N +C+ ++ CD +
Sbjct: 2996 NEFTCGYGLCIPKIFRCDRHNDCGDYSDERG-CLYQTCQQNQFTCQNGRCISKTFVCDED 3054
Query: 9487 DDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLC 9666
+DC DGSDE C +F+C +G CI+ K+C+ DC D SDE C
Sbjct: 3055 NDCGDGSDEL----MHLCHTPEPTCPPHEFKCDNGRCIEMMKLCNHLDDCLDNSDEKG-C 3109
Query: 9667 FIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNECYEGISGCSQKCD 9846
I+EC C+ C D + C C G+ + +SD+++C +++EC E CSQKC+
Sbjct: 3110 GINECHDPSISGCDHNCTDTLTSFYCSCRPGYKL-MSDKRTCVDIDECTEMPFVCSQKCE 3168
Query: 9847 DKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYELAAQGFD 10026
+ IGSY C C GY D +C++ EP+ + +N++Y+R ++IDG Y L +G D
Sbjct: 3169 NVIGSYICKCAPGYLREPDGKTCRQNS-NIEPYLIFSNRYYLRNLTIDGYFYSLILEGLD 3227
Query: 10027 NVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDWVGR 10206
NVV+LD D EK+ Y ID + + R+ L++ + ET++ H + E +AVDWV R
Sbjct: 3228 NVVALDFDRVEKRLYWIDTQRQVIERMFLNKTNK-----ETIINHRLPAAESLAVDWVSR 3282
Query: 10207 KLYMLNRQERSIRVCELDGRFCKTLIRDRIQ--------QPKAIVVHPGKGYLFFTEWSL 10362
KLY L+ + + V +L+G + L + + P+ + +HP GYL++ +W
Sbjct: 3283 KLYWLDARLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLYWADWGH 3342
Query: 10363 QPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGN 10542
+ YIGR+ +DG+ + + L WPN I IDY +D L+W DAHL I + D +G+
Sbjct: 3343 RAYIGRVGMDGTNKSV-----IISTKLEWPNGITIDYTNDLLYWADAHLGYIEYSDLEGH 3397
Query: 10543 GRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDLRIV 10722
R + H ++ +F+D +YW DWN R V + +K+ G N L T P D+ +
Sbjct: 3398 HRHTVYDGALPHPFAITIFEDTIYWTDWNTRTVEKGNKYDGSNRQTLVNTTHRPFDIHVY 3457
Query: 10723 HPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQF--VLLSDQKTCEPNCTERQF 10896
HP RQP NPCG NNGGCSHLCLI GG G+TC CPD F + LS C P C+ QF
Sbjct: 3458 HPYRQPIVSNPCGTNNGGCSHLCLIKPGGKGFTCECPDDFRTLQLSGSTYCMPMCSSTQF 3517
Query: 10897 ACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRPFQIXXX 11076
C ++ KCIP W CDG+ DC DGSDE ++C QR C +G+FQC++ NCT P +
Sbjct: 3518 LCANNE-KCIPIWWKCDGQKDCSDGSDE--LALCPQRFCRLGQFQCSDGNCTSPQTLCNA 3574
Query: 11077 XXXXXXXXXEQN--CDK-ACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEADTLCMSA 11247
E C+ CD ++C A RCIP + SDE + C A
Sbjct: 3575 HQNCPDGSDEDRLLCENHHCDSNEWQC-ANKRCIPESWQCDTFNDCEDNSDEDSSHC--A 3631
Query: 11248 ERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXE-TPEC-AQIECKKGWTR--CSSSYR 11415
R C +FRC N +CI +AW+ E EC + +T C ++YR
Sbjct: 3632 SRTCRPGQFRCANGRCIPQAWKCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFSCKTNYR 3691
Query: 11416 CIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSD 11595
CIP WA CNG DDCRDNSDE TC VG+FRC + CIP RW CD +NDCGDNSD
Sbjct: 3692 CIPKWAVCNGVDDCRDNSDEQGCEERTCHPVGDFRC-KNHHCIPLRWQCDGQNDCGDNSD 3750
Query: 11596 ELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQCD 11775
E + + R C+ESEFRC + +CIP +CD C D DE C +R C P + QC
Sbjct: 3751 EENCA----PRECTESEFRCVNQQCIPSRWICDHYNDCGDNSDERDCEMRTCHPEYFQCT 3806
Query: 11776 DGTCIAEHKWCDRKKDCPNAADELHCED--VSRRTCSPFEFECANSVCIPRKFMXXXXXX 11949
G C+ CD DC +A+DE C C FEC N VCIP +
Sbjct: 3807 SGHCVHSELKCDGSADCLDASDEADCPTRFPDGAYCQATMFECKNHVCIPPYWKCDGDDD 3866
Query: 11950 XXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSF 12129
SDE C C+ P RFRC ++R C+ ++CNG +DCG D +DE C
Sbjct: 3867 CGDGSDEELHLCLDVPCNSPNRFRCDNNR-CIYSHEVCNGVDDCG--DGTDETEEHCRKP 3923
Query: 12130 SEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKH 12309
+ C+ ++KC NG C+ CD DDCGD SDE+GC+K +T E C+
Sbjct: 3924 TP-KPCTEYEYKCGNGHCIPHDNVCDDADDCGDWSDELGCNKGKERTCAENI-----CEQ 3977
Query: 12310 ICTDVRD-GFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGSYLCRCHEDYE 12486
CT + + GF C C GF + C+DI+EC TC Q C NTKGSY C C + +
Sbjct: 3978 NCTQLNEGGFICSCTAGFETNVFDRTSCLDINECEQFGTCPQHCRNTKGSYECVCADGFT 4037
Query: 12487 NNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXXX 12666
+ + GK C A+G + +++ + + + +L + +
Sbjct: 4038 S---MSDRPGKRCAAEGSSPLLLLPDNVRIRKYNLSSERFSEYLQDEEYIQAVDYDWDPX 4094
Query: 12667 XPRKELMYWI---DGSE-RTIYRSAIANGNQSHEGQKLDVDFAAMGVV-PTAIAVDYTTG 12831
++Y+ +GS I R+ I N +VD V+ P IAVD+
Sbjct: 4095 DIGLSVVYYTVRGEGSRFGAIKRAYIPNFESGRNNLVQEVDLKLKYVMQPDGIAVDWVGR 4154
Query: 12832 NLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALI 13011
+++ + V + KR I V DGRY K +++ L QP A+
Sbjct: 4155 HIYWSDV-----------KNKR------------IEVAKLDGRYRKWLISTDLDQPAAIA 4191
Query: 13012 TAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKY 13191
P G + ++D G K E A M+G R I+V + + PT ++ID +RIYW D K
Sbjct: 4192 VNPKLGLMFWTDWGKEPKXESAWMNGEDRNILVFEDLGWPTGLSIDYLNNDRIYWSDFKE 4251
Query: 13192 RRVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSRESKTLYVQDKFGRGR------V 13353
++ + DG++R + + PY++D+FE+ +YW+S+E ++ Q+KFG+G+ V
Sbjct: 4252 DVIETIKYDGTDRRVIAKEAMNPYSLDIFEDQLYWISKEKGEVWKQNKFGQGKKEKTLVV 4311
Query: 13354 SVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTGFACLCPDG--IVPQ 13527
+ + + H +R + ++V + CSHLC+ P G++C CP G +
Sbjct: 4312 NPWLTQVRIFHQLRYN--------KSVPNLCKQICSHLCLLRPG-GYSCACPQGSSFIEG 4362
Query: 13528 LDGSCATQHVEALTMPKQCKCTNGGKCRLDGS----CECTSDFEGDQCE 13662
C + +P C+C +GG C D + C+C S + G CE
Sbjct: 4363 STTECDAAIELPINLPPPCRCMHGGNCYFDETDLPKCKCPSGYTGKYCE 4411
Score = 399 bits (1024), Expect = e-108
Identities = 301/1086 (27%), Positives = 485/1086 (43%), Gaps = 32/1086 (2%)
Frame = +1
Query: 3169 NSTQFQCKNGRCIPKEWKCDGENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKKCIP 3348
+S F+C +G CIP +W+CDG DC D++DEI C T C + KC++ +CIP
Sbjct: 29 DSAHFRCGSGHCIPADWRCDGTKDCSDDADEIG-----CAVVT-CQQGYFKCQSEGQCIP 82
Query: 3349 AQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXX 3528
+ +D + C++ + C N +CIP +++
Sbjct: 83 SSWVCDQDQDCDDGSDER----QDCSQSTCSSHQITCSNGQCIPSEYRCDHVRDCPDGAD 138
Query: 3529 EKLEMCGNATCAANQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCA 3708
E C TC Q +C NG C CD DC D +DE C + C +F C
Sbjct: 139 E--NDCQYPTC--EQLTCDNGACYNTSQKCDWKVDCRDSSDE--INCTEI-CLHNEFSCG 191
Query: 3709 NGRQCVPLRNHXXXXXXXXXXXXXXXXAVTAESCTPDQFKCVSSGLCIPASWKXXXXXXX 3888
NG +C+P A +C QF C SG CI +W
Sbjct: 192 NG-ECIP--RAYVCDHDNDCQDGSDEHACNYPTCGGYQFTC-PSGRCIYQNWVCDGEDDC 247
Query: 3889 XXXSDEPKFGCTSG----RQCSSDQFKC-GNGRCILNNWLCDGENDCGDGSDESSERGCK 4053
DE GC SG +CS ++ C +GRCI +CDG DC DE++
Sbjct: 248 KDNGDED--GCESGPHDVHKCSPREWSCPESGRCISIYKVCDGILDCPGREDENN----- 300
Query: 4054 TSMNARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCSFK 4233
T G C+ LCSA C ++
Sbjct: 301 --------------------------------------TSTGKYCSMTLCSA--LNCQYQ 320
Query: 4234 CHNSPNGPICSCPFGEQLVN---KTKCEPENECLDSSSCSQRCKDEKHGFTCSCDEGYEL 4404
CH +P G C CP G ++N C ++C C Q+C+ C C+EGY L
Sbjct: 321 CHETPYGGACFCPPG-YIINHNDSRTCVEFDDCQIWGICDQKCESRPGRHLCHCEEGYIL 379
Query: 4405 DVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGAIVEN-----AIALAWDSLT 4569
+ + CK D+ + I SN + D + +F +VE+ A+ +A+
Sbjct: 380 E-RGQYCKANDSFGEASIIFSNGRDLLIGD---IHGRSFRILVESQNRGVAVGVAFHYHL 435
Query: 4570 DRIYWSDIREKKILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVDSSLNTIEVAN 4749
R++W+D + K+ S + NG N + ++ E +A+DWV +Y V++ +N I++ N
Sbjct: 436 QRVFWTDTVQNKVFSVDINGLNIQEVLNVSVETPENLAVDWVNNKIYLVETKVNRIDMVN 495
Query: 4750 LEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDW---GQNPCIERASMDGTDRQIIVKT 4920
L D R L+ +N+ PRGIAVDP G +F++DW P +ERA MDG++R+ +VKT
Sbjct: 496 L-DGSYRVTLITENLGHPRGIAVDPTVGYLFFSDWESLSGEPKLERAFMDGSNRKDLVKT 554
Query: 4921 KIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFEDMM 5100
K+ WP + LD + RVY+ DS+ D+I+ V YDG R V+ + HP +++FE +
Sbjct: 555 KLGWPAGVTLDMISKRVYWVDSRFDYIETVTYDGIQRKTVVHGGSLIPHPFGVSLFEGQV 614
Query: 5101 YYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTN--PCSH 5274
+++D + K+ Y + + GV H + QP NPC N C
Sbjct: 615 FFTDWTKMAVLKANKFTETNPQVYYQASL-RPYGVTVYHSLRQP-YATNPCKDNNGGCEQ 672
Query: 5275 LCLLNNKNT-----FTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNVFGIEMNSASEKE 5439
+C+L+++ F CKC G +LD + CI + FL+ + + GI +++++
Sbjct: 673 VCVLSHRTDNDGLGFRCKCTFGFQLDTDERHCI-AVQNFLIFSSQVAIRGIPFTLSTQED 731
Query: 5440 TPVLAGMVPLSGLGNAF-DAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNGGNK 5616
MVP+SG + F +DA +F + + H I++ ++G +
Sbjct: 732 V-----MVPVSGNPSFFVGIDFDAQDSTIFFSDMSKH-----------MIFKQKIDGTGR 775
Query: 5617 TKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVI--LSNDQSXXXX 5790
+ ++ V ++ L FDW +NL + ++I ++R K R+V+ L+N +S
Sbjct: 776 EILAANRV-ENVESLAFDWISKNLYWTDSHYKSISVMRLADKTRRTVVQYLNNPRSVVVH 834
Query: 5791 XXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAIDTTNT 5970
GY+F+ D AK+ RA DGS+ L + + L + +AID +
Sbjct: 835 PFA---------GYLFFTD---WFRPAKIMRAWSDGSHLLPVINTTLGWPNGLAIDWAAS 882
Query: 5971 RVYFSEAKAGRISSVTYDGQDRHYV-LSDGGRQPNGLAFYGDRLFYADSAFDS-IEVATI 6144
R+Y+ +A +I T+DG DR + + P GLA +G+ LF+ D + I V
Sbjct: 883 RLYWVDAYFDKIEHSTFDGLDRRRLGHIEQMTHPFGLAIFGEHLFFTDWRLGAIIRVRKA 942
Query: 6145 NGDSQPPQWTHFKKDVENLANIKA----LQPRASSSGHPCHINNGNCDHICIPLMFAQRT 6312
+G + T + + + ++K+ +Q +++ P H NG+C H C P+ QR
Sbjct: 943 DGG----EMTVIRSGIAYILHLKSYDVNIQTGSNACNQPTH-PNGDCSHFCFPVPNFQRV 997
Query: 6313 CTCANG 6330
C C G
Sbjct: 998 CGCPYG 1003
Score = 336 bits (862), Expect = 9e-90
Identities = 210/713 (29%), Positives = 326/713 (45%), Gaps = 48/713 (6%)
Frame = +1
Query: 8875 QQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNL- 9051
Q+C + RC SG CIP W+CDG DCSD DE C C Y F+C +
Sbjct: 26 QECDSAHFRCGSGHCIPADWRCDGTKDCSDDADE--IGCAVVT----CQQGY-FKCQSEG 78
Query: 9052 KCISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCD 9231
+CI +++ R C TC+ + C++ +CIP + CD
Sbjct: 79 QCIPSSWV--CDQDQDCDDGSDERQDCSQSTCSSHQITCSNG--------QCIPSEYRCD 128
Query: 9232 GDVTCAGGEDES-------------TELCKTEKKECN-------------------KGEF 9315
C G DE+ C ++C+ EF
Sbjct: 129 HVRDCPDGADENDCQYPTCEQLTCDNGACYNTSQKCDWKVDCRDSSDEINCTEICLHNEF 188
Query: 9316 RCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCANHKCVPNSWKCDGNDDC 9495
C N CI + CD DNDC DGSDEHA C Y +C F C + +C+ +W CDG DDC
Sbjct: 189 SCGNGECIPRAYVCDHDNDCQDGSDEHA-CNYPTCGGYQFTCPSGRCIYQNWVCDGEDDC 247
Query: 9496 EDGSDEKDCPKNSASAQKASKCSNGQFQC-TSGECIDDAKVCDRNFDCTDRSDESSLCFI 9672
+D DE C + KCS ++ C SG CI KVCD DC R DE++
Sbjct: 248 KDNGDEDGC---ESGPHDVHKCSPREWSCPESGRCISIYKVCDGILDCPGREDENNTSTG 304
Query: 9673 DECS--LAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNEC-YEGISGCSQKC 9843
CS L C+ +C + G C C G+ I+ +D ++C ++C GI C QKC
Sbjct: 305 KYCSMTLCSALNCQYQCHETPYGGACFCPPGYIINHNDSRTCVEFDDCQIWGI--CDQKC 362
Query: 9844 DDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYELAAQGF 10023
+ + G + C C +GY L + CK + E + +N + I G + + +
Sbjct: 363 ESRPGRHLCHCEEGYILERGQY-CKANDSFGEASIIFSNGRDLLIGDIHGRSFRILVESQ 421
Query: 10024 DNVVSLDIDLTE--KKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDW 10197
+ V++ + ++ + D + ++ VD++ + + + VL +V E +AVDW
Sbjct: 422 NRGVAVGVAFHYHLQRVFWTDTVQNKVFSVDINGL-----NIQEVLNVSVETPENLAVDW 476
Query: 10198 VGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFFTEW---SLQP 10368
V K+Y++ + I + LDG + TLI + + P+ I V P GYLFF++W S +P
Sbjct: 477 VNNKIYLVETKVNRIDMVNLDGSYRVTLITENLGHPRGIAVDPTVGYLFFSDWESLSGEP 536
Query: 10369 YIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGR 10548
+ R +DGS L + LGWP + +D S R++W D+ + I + +DG R
Sbjct: 537 KLERAFMDGSNRKD-----LVKTKLGWPAGVTLDMISKRVYWVDSRFDYIETVTYDGIQR 591
Query: 10549 RHI--PAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDLRIV 10722
+ + H + +F+ +++ DW VL+ +K+T N + + P + +
Sbjct: 592 KTVVHGGSLIPHPFGVSLFEGQVFFTDWTKMAVLKANKFTETNPQVYYQASLRPYGVTVY 651
Query: 10723 HPMRQPAYPNPCGDNNGGCSHLCLIG----AGGNGYTCSCPDQFVLLSDQKTC 10869
H +RQP NPC DNNGGC +C++ G G+ C C F L +D++ C
Sbjct: 652 HSLRQPYATNPCKDNNGGCEQVCVLSHRTDNDGLGFRCKCTFGFQLDTDERHC 704
Score = 239 bits (609), Expect = 2e-60
Identities = 187/684 (27%), Positives = 283/684 (41%), Gaps = 27/684 (3%)
Frame = +1
Query: 130 ASVNTASSVCNENDFRCNDGKCIRTEW---XXXXXXXXXXXXXXXXXPHPGCKSDQWQCD 300
AS + C ++F+C+ G+CI +EW + C ++ C
Sbjct: 2897 ASCGHSERTCLADEFKCDGGRCIPSEWICDGDNDCGDMSDEDKRHQCQNQNCSDSEFLCV 2956
Query: 301 TYTWHSVSCIAEYQRCDNITDCADGSDE-KDCPASTVDCSSQNVFMCADGRQCFDVSKKC 477
CI + CD DC DG DE ++C T S+N F C G C +C
Sbjct: 2957 NDRPPDRRCIPQSWVCDGDVDCTDGYDENQNCTRRT---CSENEFTCGYG-LCIPKIFRC 3012
Query: 478 DGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDE-PDTC 654
D DC D SDE+ + C Q QF C +CI K++VCD DC DGSDE C
Sbjct: 3013 DRHNDCGDYSDERGCL---YQTCQQNQFTC-QNGRCISKTFVCDEDNDCGDGSDELMHLC 3068
Query: 655 EFKK--CTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCI 828
+ C +EF+C N RC C++ DDC DNSDE C
Sbjct: 3069 HTPEPTCPPHEFKCDNGRCIEMMKLCNHLDDCLDNSDEKGC------------------- 3109
Query: 829 DQLKLCDGSKDCADGADEQQCSQNLCPSL-GCQAGCHPSPHGGECTCPSGYKL-DDRFHR 1002
G +C D PS+ GC C + C+C GYKL D+ R
Sbjct: 3110 -------GINECHD------------PSISGCDHNCTDTLTSFYCSCRPGYKLMSDK--R 3148
Query: 1003 TCSDINECAEFGY-CDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNAD 1179
TC DI+EC E + C Q C N + C C + + + + N + Y + +N
Sbjct: 3149 TCVDIDECTEMPFVCSQKCENVIGSYICKC-APGYLREPDGKTCRQNSNIEPYLIFSNRY 3207
Query: 1180 KMKLFVARREG-LYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTD---RLAHSAF 1347
++ +G Y L + D + +DFD +++++W D ++ F
Sbjct: 3208 YLRNLTI--DGYFYSLILEGLDN----------VVALDFDRVEKRLYWIDTQRQVIERMF 3255
Query: 1348 SADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLL 1527
+ E I+ L LAVDW++ LY +++ + VS +G R +L
Sbjct: 3256 LNKTNKETIINH-------RLPAAESLAVDWVSRKLYWLDARLDGLFVSDLNGGHRRMLA 3308
Query: 1528 ADGLTL--------PLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVS 1674
+ P +AL P G +++ ++ + MDGTN+ +++T +
Sbjct: 3309 QHCVDANNTFCFDNPRGLALHPQYGYLYWADWGHRAYIGRVGMDGTNKSVIISTKLEWPN 3368
Query: 1675 GIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWT 1854
GI +D T +YW D + +E D +G+ R V G +PHPF + +F+ +YWTDW
Sbjct: 3369 GITIDYTNDLLYWADAHLGYIEYSDLEGHHRHTVYDG--ALPHPFAITIFEDTIYWTDWN 3426
Query: 1855 RLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPC--TNA 2028
V + K+ + NT + P I YHP QP + NPC N
Sbjct: 3427 TRTVEKGNKYDGSNRQTLVNTTHR--PFDIHVYHPYRQP----------IVSNPCGTNNG 3474
Query: 2029 DCEGMCILSKDNGGFGVGYKCACP 2100
C +C++ G G+ C CP
Sbjct: 3475 GCSHLCLIKPG----GKGFTCECP 3494
Score = 239 bits (609), Expect = 2e-60
Identities = 217/773 (28%), Positives = 312/773 (40%), Gaps = 109/773 (14%)
Frame = +1
Query: 133 SVNTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTW 312
S + AS C FRC +G+CI W P C S CD +T
Sbjct: 3627 SSHCASRTCRPGQFRCANGRCIPQAW---KCDVDNDCGDHSDEPIEECMSSAHLCDNFTE 3683
Query: 313 HSVS----CIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCD 480
S CI ++ C+ + DC D SDE+ C T C F C + C + +CD
Sbjct: 3684 FSCKTNYRCIPKWAVCNGVDDCRDNSDEQGCEERT--CHPVGDFRCKN-HHCIPLRWQCD 3740
Query: 481 GKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEF 660
G+ DC D SDE++ R C + +FRC ++ QCI W+CD DC D SDE D CE
Sbjct: 3741 GQNDCGDNSDEENCAPRE---CTESEFRCVNQ-QCIPSRWICDHYNDCGDNSDERD-CEM 3795
Query: 661 KKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGT-----GH- 822
+ C FQC + C + +CD DC D SDE +C R P G + C T H
Sbjct: 3796 RTCHPEYFQCTSGHCVHSELKCDGSADCLDASDEADC-PTRFPDGAY-CQATMFECKNHV 3853
Query: 823 CIDQLKLCDGSKDCADGADEQ---------------QCSQNLCPSL--------GCQAGC 933
CI CDG DC DG+DE+ +C N C C G
Sbjct: 3854 CIPPYWKCDGDDDCGDGSDEELHLCLDVPCNSPNRFRCDNNRCIYSHEVCNGVDDCGDGT 3913
Query: 934 HPS------PHGGECT-----CPSGYKLDDRFHRTCSDINECAEF--------------- 1035
+ P CT C +G+ + C D ++C ++
Sbjct: 3914 DETEEHCRKPTPKPCTEYEYKCGNGHCIP--HDNVCDDADDCGDWSDELGCNKGKERTCA 3971
Query: 1036 -GYCDQLCAN-HRPGFTCSCLG----------DCFTL----QMEHGPGKDNLTMRGY-CV 1164
C+Q C + GF CSC C + Q P T Y CV
Sbjct: 3972 ENICEQNCTQLNEGGFICSCTAGFETNVFDRTSCLDINECEQFGTCPQHCRNTKGSYECV 4031
Query: 1165 -----SNNADKM-KLFVARREGLYRLNPKNPDEEVKKLASGEF---------IYGIDFDY 1299
++ +D+ K A L P N L+S F I +D+D+
Sbjct: 4032 CADGFTSMSDRPGKRCAAEGSSPLLLLPDNVRIRKYNLSSERFSEYLQDEEYIQAVDYDW 4091
Query: 1300 -----GDRKIFWTDRLAHSAFSA--------DVDDEGEISQIKKLSLKSLVYPRCLAVDW 1440
G +++T R S F A + Q L LK ++ P +AVDW
Sbjct: 4092 DPXDIGLSVVYYTVRGEGSRFGAIKRAYIPNFESGRNNLVQEVDLKLKYVMQPDGIAVDW 4151
Query: 1441 ITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTN---QLKLE 1611
+ +Y + ++RI+V+ DG R L++ L P IA++P G MF+T+ + K E
Sbjct: 4152 VGRHIYWSDVKNKRIEVAKLDGRYRKWLISTDLDQPAAIAVNPKLGLMFWTDWGKEPKXE 4211
Query: 1612 AAAMDGTNRRTLVNTHTHQVSGIVVD-ITAKRVYWVDPKVDRLESIDYQGNDRRIVA-QG 1785
+A M+G +R LV +G+ +D + R+YW D K D +E+I Y G DRR++A +
Sbjct: 4212 SAWMNGEDRNILVFEDLGWPTGLSIDYLNNDRIYWSDFKEDVIETIKYDGTDRRVIAKEA 4271
Query: 1786 MNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMA 1965
MN P+ L +F+ LYW + V + KFG K N + + +H +
Sbjct: 4272 MN----PYSLDIFEDQLYWISKEKGEVWKQNKFGQGKK--EKTLVVNPWLTQVRIFHQLR 4325
Query: 1966 QPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNG 2124
+ N C C +C+L GY CACP G + G
Sbjct: 4326 ---------YNKSVPNLCKQI-CSHLCLLRPG------GYSCACPQGSSFIEG 4362
Score = 222 bits (565), Expect = 2e-55
Identities = 196/737 (26%), Positives = 297/737 (39%), Gaps = 60/737 (8%)
Frame = +1
Query: 11503 DVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRC-NDGKCIPG 11679
D FRC SG CIP W CD DC D++DE+ C T C + F+C ++G+CIP
Sbjct: 29 DSAHFRCG-SGHCIPADWRCDGTKDCSDDADEI--GCAVVT--CQQGYFKCQSEGQCIPS 83
Query: 11680 SKVCDGTIQCSDGLDESQ-------------CTLRRCLPGHRQ----------------- 11769
S VCD C DG DE Q C+ +C+P +
Sbjct: 84 SWVCDQDQDCDDGSDERQDCSQSTCSSHQITCSNGQCIPSEYRCDHVRDCPDGADENDCQ 143
Query: 11770 --------CDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFECANSVCIPRK 11925
CD+G C + CD K DC +++DE++C ++ C EF C N CIPR
Sbjct: 144 YPTCEQLTCDNGACYNTSQKCDWKVDCRDSSDEINCTEI----CLHNEFSCGNGECIPRA 199
Query: 11926 FMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDE 12105
++ SDE + C C +F C R C+ +C+G +DC N D
Sbjct: 200 YVCDHDNDCQDGSDEHA--CNYPTCG-GYQFTCPSGR-CIYQNWVCDGEDDCKDNGDED- 254
Query: 12106 HLSMCSSFSEYGDCSSDQFKC-ANGKCVNGTVACDRKDDCGDASDEIGCS--KHGGKTSC 12276
S + CS ++ C +G+C++ CD DC DE S K+ T C
Sbjct: 255 --GCESGPHDVHKCSPREWSCPESGRCISIYKVCDGILDCPGREDENNTSTGKYCSMTLC 312
Query: 12277 EAFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGS 12456
A C++ C + G C C G+ + + C++ D+C C Q C + G
Sbjct: 313 SAL----NCQYQCHETPYGGACFCPPGYIINHNDSRTCVEFDDCQIWGICDQKCESRPGR 368
Query: 12457 YLCRCHEDYENNVVVGSMTGKDCRAK---GDAANVMIGADDSLVQLSLHGSGTNRHXXXX 12627
+LC C E Y G+ C+A G+A+ + D L+ +HG
Sbjct: 369 HLCHCEEGYILE------RGQYCKANDSFGEASIIFSNGRDLLIG-DIHGRSFRILVESQ 421
Query: 12628 XXXXXXXXXXXXXXPRKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTA 12807
R ++W D + ++ S NG E + V+ P
Sbjct: 422 NRGVAVGVAFHYHLQR---VFWTDTVQNKVF-SVDINGLNIQEVLNVSVE------TPEN 471
Query: 12808 IAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGH 12987
+AVD+ +++ N ID N DG Y ++ +
Sbjct: 472 LAVDWVNNKIYLVETKVN---------------RIDMVNL--------DGSYRVTLITEN 508
Query: 12988 LQQPTALITAPSAGRICYSD---AGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGK 13158
L P + P+ G + +SD K+E A MDG++R+ +VK + P + +D
Sbjct: 509 LGHPRGIAVDPTVGYLFFSDWESLSGEPKLERAFMDGSNRKDLVKTKLGWPAGVTLDM-I 567
Query: 13159 GNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHI---PYAVDVFENHIYWLSRESKTLYVQ 13329
R+YWVD ++ ++ V DG +R TVVH + P+ V +FE +++ +
Sbjct: 568 SKRVYWVDSRFDYIETVTYDGIQRKTVVHGGSLIPHPFGVSLFEGQVFFTDWTKMAVLKA 627
Query: 13330 DKFGRGRVSVL--ASDLEDGHTV--RVSQKYAKDTQRTVSGCERAQCSHLCVSLPST--- 13488
+KF V AS G TV + Q YA + + +G C +CV T
Sbjct: 628 NKFTETNPQVYYQASLRPYGVTVYHSLRQPYATNPCKDNNG----GCEQVCVLSHRTDND 683
Query: 13489 --GFACLCPDGIVPQLD 13533
GF C C G QLD
Sbjct: 684 GLGFRCKCTFGF--QLD 698
Score = 140 bits (353), Expect = 9e-31
Identities = 101/332 (30%), Positives = 129/332 (38%), Gaps = 10/332 (3%)
Frame = +1
Query: 10879 CTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRP 11058
C F CG CIP W CDG DC D +DE G C C G F
Sbjct: 28 CDSAHFRCGS--GHCIPADWRCDGTKDCSDDADEIG---CAVVTCQQGYF---------- 72
Query: 11059 FQIXXXXXXXXXXXXEQNCDKACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEADTLC 11238
KC + G+CIP + SDE
Sbjct: 73 ----------------------------KCQSEGQCIPSSWVCDQDQDCDDGSDERQDCS 104
Query: 11239 MSAERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXET----PECAQIECKKGWTRCSS 11406
S C++ + C+N +CI +R E P C Q+ C G
Sbjct: 105 QS---TCSSHQITCSNGQCIPSEYRCDHVRDCPDGADENDCQYPTCEQLTCDNG------ 155
Query: 11407 SYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMCDTENDCGD 11586
C C+ + DCRD+SDE C EF C +G+CIPR ++CD +NDC D
Sbjct: 156 --ACYNTSQKCDWKVDCRDSSDE--INCTEICLHNEFSCG-NGECIPRAYVCDHDNDCQD 210
Query: 11587 NSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQC-----TLRRC 11751
SDE +C T C +F C G+CI + VCDG C D DE C + +C
Sbjct: 211 GSDE--HACNYPT--CGGYQFTCPSGRCIYQNWVCDGEDDCKDNGDEDGCESGPHDVHKC 266
Query: 11752 LPGHRQC-DDGTCIAEHKWCDRKKDCPNAADE 11844
P C + G CI+ +K CD DCP DE
Sbjct: 267 SPREWSCPESGRCISIYKVCDGILDCPGREDE 298
Score = 139 bits (351), Expect = 2e-30
Identities = 115/414 (27%), Positives = 164/414 (38%), Gaps = 19/414 (4%)
Frame = +1
Query: 8389 NFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNR-RCIDSAKKCNH 8565
+F+CG G CI CD DC+D +DE C +C + Y C + +CI S+ C+
Sbjct: 32 HFRCGSGHCIPADWRCDGTKDCSDDADEIG--CAVVTCQQGYFKCQSEGQCIPSSWVCDQ 89
Query: 8566 IDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHD-EQVSDESLATCPG 8742
DC DGSDE S C+ CSNG CI CD DC D +D TC
Sbjct: 90 DQDCDDGSDERQDCSQSTCSSHQITCSNGQCIPSEYRCDHVRDCPDGADENDCQYPTCEQ 149
Query: 8743 LPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCI 8922
L D C + CD DC D +DE + C + C + C +G CI
Sbjct: 150 LTCD----------NGACYNTSQKCDWKVDCRDSSDE--INC-TEICLHNEFSCGNGECI 196
Query: 8923 PETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXX 9102
P + CD DNDC DG DE N G Y F C + +CI + ++
Sbjct: 197 PRAYVCDHDNDCQDGSDEHACNYPTCGG-------YQFTCPSGRCIYQNWVCDGEDDCKD 249
Query: 9103 XXXXHSRHGCGN-----RTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDES 9267
GC + C+ +E+ C + + CI +CDG + C G EDE+
Sbjct: 250 NG---DEDGCESGPHDVHKCSPREWSCPESGR-------CISIYKVCDGILDCPGREDEN 299
Query: 9268 TELCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDC-------LDGSDEHANCTYSSCQP 9426
+ K C+ CS +C + E C ++ +D + CQ
Sbjct: 300 N---TSTGKYCSM--TLCSALNCQYQCHETPYGGACFCPPGYIINHNDSRTCVEFDDCQ- 353
Query: 9427 DFFQCANHKCV--PNSWKCDGNDDCEDG---SDEKDCPKNSASAQKASKCSNGQ 9573
+ + KC P C CE+G + C N + + + SNG+
Sbjct: 354 -IWGICDQKCESRPGRHLC----HCEEGYILERGQYCKANDSFGEASIIFSNGR 402
Score = 130 bits (327), Expect = 9e-28
Identities = 78/229 (34%), Positives = 110/229 (47%), Gaps = 15/229 (6%)
Frame = +1
Query: 9274 LCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCANH- 9450
L +EC+ FRC + HCI + W CDG DC D +DE C +CQ +F+C +
Sbjct: 20 LAPASGQECDSAHFRCGSGHCIPADWRCDGTKDCSDDADE-IGCAVVTCQQGYFKCQSEG 78
Query: 9451 KCVPNSWKCDGNDDCEDGSDEK-DCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRN 9627
+C+P+SW CD + DC+DGSDE+ DC + S CS+ Q C++G+CI CD
Sbjct: 79 QCIPSSWVCDQDQDCDDGSDERQDCSQ--------STCSSHQITCSNGQCIPSEYRCDHV 130
Query: 9628 FDCTDRSDESSLCFIDECSLAEKPLCEQKCMD--------MKIGYKCDCFEGFAIDISDQ 9783
DC D +DE+ + P CEQ D K +K DC D SD+
Sbjct: 131 RDCPDGADEND---------CQYPTCEQLTCDNGACYNTSQKCDWKVDC-----RDSSDE 176
Query: 9784 KSC-----HNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSC 9915
+C HN C G +C + +Y C + Q SD+H+C
Sbjct: 177 INCTEICLHNEFSCGNG------ECIPR--AYVCDHDNDCQDGSDEHAC 217
Score = 90.1 bits (222), Expect = 1e-15
Identities = 81/286 (28%), Positives = 113/286 (39%), Gaps = 10/286 (3%)
Frame = +1
Query: 11743 RRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFEC-ANSVCIP 11919
+ C H +C G CI CD KDC + ADE+ C V TC F+C + CIP
Sbjct: 26 QECDSAHFRCGSGHCIPADWRCDGTKDCSDDADEIGCAVV---TCQQGYFKCQSEGQCIP 82
Query: 11920 RKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFS 12099
++ SDE +C + C +H C N C P+++
Sbjct: 83 SSWVCDQDQDCDDGSDE-RQDCSQSTCS-------SHQITCSN--------GQCIPSEYR 126
Query: 12100 DEHLSMCSSFSEYGDC---SSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSK--HGG 12264
+H+ C ++ DC + +Q C NG C N + CD K DC D+SDEI C++
Sbjct: 127 CDHVRDCPDGADENDCQYPTCEQLTCDNGACYNTSQKCDWKVDCRDSSDEINCTEICLHN 186
Query: 12265 KTSCEAFGNNGGC---KHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNN-TCTQ 12432
+ SC NG C ++C D C+DG S + + C G TC
Sbjct: 187 EFSC----GNGECIPRAYVCDHDND-----CQDG------SDEHACNYPTCGGYQFTCPS 231
Query: 12433 LCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADD 12570
RC Y+N V G DC+ GD G D
Sbjct: 232 ----------GRC--IYQNWVCDGE---DDCKDNGDEDGCESGPHD 262
Score = 84.7 bits (208), Expect = 6e-14
Identities = 55/181 (30%), Positives = 86/181 (47%), Gaps = 25/181 (13%)
Frame = +1
Query: 3925 SGRQCSSDQFKCGNGRCILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACEN 4104
SG++C S F+CG+G CI +W CDG DC SD++ E GC C + C++
Sbjct: 24 SGQECDSAHFRCGSGHCIPADWRCDGTKDC---SDDADEIGCAVV----TCQQGYFKCQS 76
Query: 4105 DQETCIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCS--------FKC---HNSPN 4251
+ + CIP +CD C G+DE C++ CS+ + CS ++C + P+
Sbjct: 77 EGQ-CIPSSWVCDQDQDCDDGSDERQDCSQSTCSSHQITCSNGQCIPSEYRCDHVRDCPD 135
Query: 4252 G--------PIC---SCPFGEQLVNKTKCEPENECLDSS---SCSQRCKDEKHGFTCSCD 4389
G P C +C G KC+ + +C DSS +C++ C + F+C
Sbjct: 136 GADENDCQYPTCEQLTCDNGACYNTSQKCDWKVDCRDSSDEINCTEICLHNE--FSCGNG 193
Query: 4390 E 4392
E
Sbjct: 194 E 194
Score = 46.6 bits (109), Expect = 0.018
Identities = 26/86 (30%), Positives = 38/86 (43%), Gaps = 3/86 (3%)
Frame = +1
Query: 12109 LSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSK---HGGKTSCE 12279
L C + + +C S F+C +G C+ CD DC D +DEIGC+ G C+
Sbjct: 16 LVACLAPASGQECDSAHFRCGSGHCIPADWRCDGTKDCSDDADEIGCAVVTCQQGYFKCQ 75
Query: 12280 AFGNNGGCKHICTDVRDGFYCHCRDG 12357
+ G +C +D C DG
Sbjct: 76 SEGQCIPSSWVCDQDQD-----CDDG 96
>gi|47210425|emb|CAF92450.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 4260
Score = 2372 bits (6148), Expect = 0.0
Identities = 1488/4485 (33%), Positives = 2196/4485 (48%), Gaps = 210/4485 (4%)
Frame = +1
Query: 1345 FSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVL 1524
FS D+D S ++ + S+ YP LAVDW+ N LY++E+ RIDV +DG R L
Sbjct: 3 FSVDMDG----SNVQVVLNVSVDYPENLAVDWVNNKLYVVEASVNRIDVVDFDGSNRVTL 58
Query: 1525 LADGLTLPLDIALDPLRGEMFFTN------QLKLEAAAMDGTNRRTLVNTHTHQVSGIVV 1686
+ + L P +A+DP G MFFT+ Q LE A MDGTNR ++ T SGI +
Sbjct: 59 ITENLGNPRGVAVDPTVGYMFFTDWEAINGQPGLERAFMDGTNRYGIIGTKLGWPSGITL 118
Query: 1687 DITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGV 1866
DI AKR+YWVD + D +E+ Y G R+ V G VVPHPFG++LF+ +Y+TDWT++ V
Sbjct: 119 DIEAKRIYWVDSRYDYIETATYDGVHRKTVVHGGAVVPHPFGISLFEHSVYFTDWTKMAV 178
Query: 1867 IQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPC--TNADCEG 2040
++ KF ++ ++NPC CE
Sbjct: 179 MRANKF---------------------------------TDSSPPSVQNPCGTNRGGCEH 205
Query: 2041 MCILSKDNGGFGVGYKCACPIGQKL-VNGKRCIDSIDYLLFSSNKIVRGIFPEINEKALA 2217
+C+LS + G+GY+C C +G L +GK C +LLFSS VRGI N +
Sbjct: 206 ICVLSHQSDNGGLGYRCKCRMGYDLHADGKHCFAVRHFLLFSSQLAVRGI--PFNLSSQE 263
Query: 2218 EAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGL 2397
+ +LP++ IG+ F E DV F++D + I++ + DG G + DG+
Sbjct: 264 DIILPVTGSPSYFIGVDFSAEDDV----IFFSDTAKDMIFKQKVDGTGREVLTANRVDGV 319
Query: 2398 FSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKG 2577
+++DWISK LY+ D S+ V+K+ + RR ++ L +P ++VVHP G
Sbjct: 320 EDLAYDWISKNLYWTDPRYRSISVMKVADKS--------RRAIVRNLNNPRAIVVHPLIG 371
Query: 2578 LLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMD 2757
+F+ + RPA I R DG + I NTTLG P+ +AID+ RL W D I +
Sbjct: 372 YIFWTDWYRPAKIMRAWGDGSHALSIVNTTLGWPNGLAIDWNAMRLYWVDAFFDKIEHSN 431
Query: 2758 FDGKNVVKLDIDNPI--PVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVRE------ 2913
FDG+N + LD I P +TI Y YY R I RV K +GG I+R
Sbjct: 432 FDGQNRISLDRITQISHPFGLTIFEGYAYYTDWRLGGIVRVRKTDGGEMVIIRRGISHIM 491
Query: 2914 ----FGADERSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCA 3081
F + ++ F+L C+ P D C+ CF P + C
Sbjct: 492 HVKSFSSTSQTGFNL--CNRLTNPNGD-----------CSHFCFPVPDS------QRVCG 532
Query: 3082 CRQGFMINKENNHSCQKDPAEKIEQL-CSSNSTQFQCKNGRCIPKEWKCDGENDCLDESD 3258
C G + N +C +DP+ + L C +NS F C NG+C+P ++CDG +DC D SD
Sbjct: 533 CPYGMKL-LPNQRTCVEDPSNEPPTLQCGANS--FSCGNGKCVPNSYRCDGVDDCHDNSD 589
Query: 3259 EIDEKGDKC-FHETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPV 3435
E+D C + + C+ C NT+ C+PA C
Sbjct: 590 EVD-----CGVNNSTCSPTAFTCANTR-CVPAAWRCDGHNDCFDNSDESS--CPAPAPGT 641
Query: 3436 CAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNATCAANQFSCANGRCIPIYWL 3615
C A +F C NHRC+P W+ E G+ TC QF C + RCI ++
Sbjct: 642 CPANQFTCSNHRCVPHSWRCDTDNDCGDGSDEADCQLGS-TCHPGQFQCPDHRCIDPSYV 700
Query: 3616 CDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQCVP--LRNHXXXXXXXXXXXXXXXX 3789
CDGD DC DG DE R C+A +F+CA+G QC+ R
Sbjct: 701 CDGDRDCVDGADE---RGCIYNCTANEFKCASGHQCINGYYRCDGVFDCTDRSDERACPT 757
Query: 3790 AVTAESCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKCGNG 3969
+F+C S G CIP++W+ SDE C R C S F+C NG
Sbjct: 758 RPPGMCHHESEFQCQSDGTCIPSTWECDGHPDCEDSSDE-HHACPP-RTCPSTFFRCDNG 815
Query: 3970 RCILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDGK 4149
C+L +W+CDG+NDC D SDE R C T +CP C CI L +CD
Sbjct: 816 NCVLRSWICDGDNDCRDMSDE---RDCPTP--PFRCPSWQWQCPG-HSVCINLTTVCDNT 869
Query: 4150 THCPGGTDEGGRCARDLCSADRAGCSFKCHNSPNGPICSCPFGEQLVNKTK-CEPENECL 4326
CP G DE C ++ CS + AGC+ C P G C+CP G QL N +K C +EC
Sbjct: 870 PDCPNGADESPLCNQESCSDNNAGCTHGCIQGPFGAQCTCPVGYQLSNDSKTCGDVDECS 929
Query: 4327 DSSSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSD--HK 4500
CSQ C +E+ F C C +GY L+ D+RTCKV+D ++ + V++RN+I D +
Sbjct: 930 PPGICSQHCFNERGSFRCHCQDGYALEADQRTCKVSD-LRQAFLLVASRNQIVQDDITSQ 988
Query: 4501 LDNWHTFGAIVENAIALAWDSLTDRIYWSDIREKKILSANRNGTNATVFIADGLDITEGI 4680
+ H+ N +AL +DS+TDR+YWSD + +I SA+ NG++ TV G+ +TE +
Sbjct: 989 PNVVHSLVRDGRNIVALDFDSVTDRVYWSDTSQDRIWSASNNGSDRTVIFDSGVTVTESL 1048
Query: 4681 ALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKG--VMFWTDW 4854
A+DWVGRNLYW D L T+EV+ L D RT+LV +NV+ PRG+ +DPR +MFWTDW
Sbjct: 1049 AVDWVGRNLYWTDYVLETVEVSKL-DGTHRTVLVSENVTNPRGLVLDPRSSAHLMFWTDW 1107
Query: 4855 GQNPCIERASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRT 5034
G+NP IERASMDG R +IV +K+YWPN + +DY + +YFAD+ LDFID+ +Y+G+ R
Sbjct: 1108 GRNPRIERASMDGKLRTVIVNSKLYWPNGLTIDYPNNLLYFADAYLDFIDYCDYNGNNRK 1167
Query: 5035 QVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAV 5214
QVLAS +QHPHA+ IFED +Y++DR + ++ K+ +G + +G+VAV
Sbjct: 1168 QVLASDLVLQHPHAITIFEDFVYWTDRYINRVMRAHKW-HGENQTVMLFNLPQPMGLVAV 1226
Query: 5215 HPVLQPVIKNNPCSTNPCSHLCLLNNKNT--FTCKCPMGEKLDASGKKCIDDAKPFLVII 5388
HP QP N C +PCSH+CLL+ ++C CP G L A C PFLV++
Sbjct: 1227 HPARQPA-GGNSCLRSPCSHICLLSAVGPAYYSCACPSGWTLAADQITCTRVEDPFLVVV 1285
Query: 5389 QKTNVFGIEMNSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQI 5568
+ + ++GI +N + MVP++GL N +D +D + ++ +EH
Sbjct: 1286 RDSIIYGISLNPEDKSND----AMVPVAGLQNGYDVDFDDNEQIIYWVEHPGE------- 1334
Query: 5569 TTDSAIYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGK-Q 5745
I+ +G N+T+ +A+ L DW +NL N TQ+IE+++ +G+ Q
Sbjct: 1335 -----IHSVKSDGTNRTEFAPAAILGSPVGLALDWITQNLYYTNPSTQSIEVLKLRGEVQ 1389
Query: 5746 YRSVILSNDQSXXXXXXXXXXXXXXXKGYVFWLDRGGGAA-DAKVARAGLDGSNPLVIAS 5922
YR +++N+ S +G ++W D+G + AKVA A +DGSNP+ + +
Sbjct: 1390 YRKTLITNNGSPTGAGSPVGIAVDPARGKLYWTDQGTESGIPAKVASANMDGSNPVNLFT 1449
Query: 5923 NDLAELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLF 6102
N+L ++ + +D ++Y++ G I S DG +R +++ G P G+A YG L+
Sbjct: 1450 NNLDHIEFLTVDIRENKLYWAVTSTGAIESGDPDGTNRITIVT-GLSHPWGVAVYGSHLY 1508
Query: 6103 YADSAFDSIE-VATINGDSQPPQWTHFKKDVENLANIKALQPRASSSG--HPCHINN-GN 6270
+ D F+ IE V G ++ + +V L +K + R +S+G + C NN G
Sbjct: 1509 FTDRDFEVIERVDKTTGTNR----VVLRDNVSGLRVLK-VHYRETSAGVSNGCTDNNMGA 1563
Query: 6271 CDHICIPLMFAQRTCTCANGY-VKDGQTSCKLFDESFVIVATKTKVIGYPIDETQSKGVA 6447
C+ IC+P TC CA G+ + +C + +S+V+++T + + G+ + E + A
Sbjct: 1564 CEQICLPAPQGFFTCACATGFKLNTDNRTCAPY-QSYVVISTLSAIKGFSL-EGEDHSEA 1621
Query: 6448 MEPIGGLSITG--VDYDYESKTIYVAEASGI---NKGITAYTIGESSPRAVIRDSIGSLT 6612
M P+ G +D S IY + S G+ S R+++ IG
Sbjct: 1622 MVPVAGRGRNALHIDVHMASGFIYWCDFSSTVAAQNGVRRIKPDGSGLRSIVTSGIGRNG 1681
Query: 6613 IKSLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYW 6792
I+ +A+DW N+YF N T +EV +L+ T+R++LL T+ + P I VDP RYL+W
Sbjct: 1682 IRGIAVDWAAGNLYFTNAFLTETYVEVLRLNTTFRRVLLKTQVDMPRHIVVDPRRRYLFW 1741
Query: 6793 ADQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGG 6972
AD GQ P I+R+ LDG+ R ++VSSGI P L +D S +YW D +D I RV GG
Sbjct: 1742 ADYGQHPKIERALLDGTNRTILVSSGIVTPRGLALDWQSGYVYWVDDSLDMIARVSPQGG 1801
Query: 6973 TPELVR--SDIASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDI 7146
E+VR S + G+ + ++ W D L+K+FRA+ +P T PT + ++ +
Sbjct: 1802 ETEVVRYGSRYPTPYGITVFENSIIWVDRNLKKVFRASKEPGSTE---QPTVIRDNINML 1858
Query: 7147 GDVAVFSSNNQPRASSPCQITDNLRKSP-CTQLCFATP----GTQTPTCSCARGVL---- 7299
DV +F + QP + + ++ C CFA P Q CSCA G L
Sbjct: 1859 RDVTIFDRHTQPTTAQELNFNPCVEENGGCAHFCFALPEYGSDGQNKVCSCAFGNLGADN 1918
Query: 7300 KGRTCEEPDTYIMFSDGDKIIDVAIEPDVKASRPLKDPFPEISNLQT---FDVDVNLRRV 7470
KG D Y++++ + + ++PD A PFP ++ +T D D+ RR+
Sbjct: 1919 KGCVVSRDD-YLIYTTESTVRSLRLDPDDHAL-----PFPVVNVPRTSVALDFDLTERRI 1972
Query: 7471 YFVVESPVGVN-ISWFSMNNAENPRLVFGASKQPHAKEIRHISDMKLDWLTQKIYFTTGR 7647
YF S G + IS+ S++ + +V A ++ + DW+ ++IY++
Sbjct: 1973 YFTQSSGAGASKISYVSLSAPTSTPVVV-------AFDLGAPDGIAYDWINRRIYYSDFV 2025
Query: 7648 GGKVMAIDTAGEHLSTIASGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAG 7827
+ ++ G + + A+ +DPC G ++W+D G +IER+ L G
Sbjct: 2026 NQSINSMSVEGSQRTVVVHVSRPRAIMLDPCRGYMYWTDWGTHA-------KIERATLGG 2078
Query: 7828 GSRKVIVSESISLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIAS-GYRAKSLD 8004
R IV+ S+ P + +D+ ++++YWAD + IE + G +R+VI S ++
Sbjct: 2079 NFRTDIVNSSLVWPNGLTLDYEDERLYWADASLQKIERSSLTGSDREVIVSTAIYPFAMT 2138
Query: 8005 IWDRWLYMSDPLSNGVFRIDKESGSGLENVVSDRRI-PGALRVFASESDVRTRNQVCNAL 8181
++D+++Y +D + ++R +K GSG ++ + P + V AS + Q C++
Sbjct: 2139 MFDQFIYWTDWNTRSIYRANKHDGSGQRVMIQNLPSRPMDIHVLASR-----KQQQCDSP 2193
Query: 8182 TSQLCKTDNGGCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSE 8361
C+ NGGC +CT + +C C G+ Y
Sbjct: 2194 ----CQQFNGGCSHICTP-------GPNGAECHC-------PSEGRWYLAD--------- 2226
Query: 8362 PAKECLP-------PYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTR-------- 8496
+K C+P P F C +G CI CD++ DC D SDE C +
Sbjct: 2227 -SKHCIPDNGTRCQPGQFTCMNGHCIRAQWKCDNENDCGDGSDELERVCGPKPKFTIVAF 2285
Query: 8497 -SCPEDYNLCTNRRCIDSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTK 8673
+C C N RC+ +C+H DDCGD SDEL C F C+NG CI +
Sbjct: 2286 HTCEPTVFTCGNGRCVPYHYRCDHYDDCGDNSDELGCLFRPCDPSREFTCNNGRCIAKDY 2345
Query: 8674 VCDGHNDCHDEQVSDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADE 8853
VC+G N+C+D SDE CP C+ + +C +TNICI + LCDG +DCGD +DE
Sbjct: 2346 VCNGINNCYDNGTSDEQ--NCPERT--CQPEQTKCQSTNICIPRSYLCDGDNDCGDMSDE 2401
Query: 8854 NQLFCMNQQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYL 9033
+ C+ C+Q RC SGRCIP W CDG DCSD DE +CT + C +
Sbjct: 2402 SPTHCVASTCSQSEFRCSSGRCIPARWYCDGGADCSDSSDEP-LSCTPQV--RTCNTEQ- 2457
Query: 9034 FQCDNLKCISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIP 9213
F+CD+ +CI+ +I RH C NRTC++ EF C +N P+ +CIP
Sbjct: 2458 FRCDDGRCIASTWICDGDNDCGDMSDEDQRHNCANRTCSNAEFTCVNNQP---PQRKCIP 2514
Query: 9214 RAWLCDGDVTCAGGEDESTELCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDE 9393
R W+CDGD CA DE + + C EF CSN CI S++ CD NDC DGSDE
Sbjct: 2515 RDWVCDGDADCADALDEHQNCTR---RSCGVNEFTCSNGLCIRSSYRCDRRNDCGDGSDE 2571
Query: 9394 HANCTYSSCQPDFFQCANHKCVPNSWKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQ 9573
CTY +CQ F C N +C+ + CDG++DC D SDE + ++ A C G+
Sbjct: 2572 QG-CTYQACQQHQFTCQNGRCISRDFVCDGDNDCGDESDELEHMCHTP----APTCPPGE 2626
Query: 9574 FQCTSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDCF 9753
F+C +G CI ++VCDRN DC+D SDE C ++EC+ C+ C D + C C
Sbjct: 2627 FRCDNGHCISLSRVCDRNDDCSDNSDEKG-CGVNECTDPSIHHCDHSCTDTPTSFICTCR 2685
Query: 9754 EGFAIDISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEME 9933
G+ + +SD K+C +VNEC E CSQ C++ +GSY C C G+ D HSC++ +
Sbjct: 2686 PGYRL-MSDGKTCDDVNECAETPRVCSQVCENTVGSYVCKCAPGFLREPDGHSCRQNS-D 2743
Query: 9934 PEPFFLLANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDL 10113
P+ + +N++Y+R +S DG Y L QG +VV+LD D +++ Y ID + RV +
Sbjct: 2744 IAPYLIFSNRYYLRNLSTDGAAYSLILQGLTSVVALDFDRVDRRLYWIDVSR----RV-I 2798
Query: 10114 DEMDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDR 10293
+ M S+ E V+ ++G EG+AVDW+ RKLY ++ ++V ELDGRF K L
Sbjct: 2799 ERMSYNGSNREVVVTGVLHG-EGLAVDWIARKLYWVDSFSDCLKVSELDGRFVKKLAEHC 2857
Query: 10294 I--------QQPKAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGW 10449
+ + P+AIV+HP G++++T+W + +IGR+ +DG+ + PI L W
Sbjct: 2858 VDANNTFCFENPRAIVLHPKYGFVYWTDWGDKAFIGRVGMDGTNKA--PIITTK---LEW 2912
Query: 10450 PNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWN 10629
PN I IDY +D+L+W DAHL+ I F D DG R + H ++ VF+D +YW DWN
Sbjct: 2913 PNGITIDYTNDKLYWSDAHLSYIEFSDLDGQHRHTVYDGNLPHPFALTVFEDTVYWTDWN 2972
Query: 10630 LREVLRCDKWTGKNETILKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGG 10809
R V + +K+ G L T P D+ + HP RQP NPC NNGGCSHLCLI GG
Sbjct: 2973 TRTVEKGNKYDGSGRQALVNTTHRPFDIHVCHPYRQPIVTNPCAVNNGGCSHLCLIRHGG 3032
Query: 10810 NGYTCSCPDQF--VLLSDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEP 10983
+TC CPD F + + C P CT Q+ C ++ +CIP W CDG+ DCRDGSDEP
Sbjct: 3033 QEHTCECPDHFLTIQIGGVTRCLPMCTSTQYRCANNE-RCIPIWWKCDGQRDCRDGSDEP 3091
Query: 10984 GESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXXEQN---CDKACDPWMFKCAA 11154
S C R C +G+FQC + NCT P + E C+ ++C A
Sbjct: 3092 --STCPVRHCRLGQFQCNDGNCTSPHLLCNSHQDCHDGSDEDPVLCATHQCENHQWQC-A 3148
Query: 11155 TGRCIPRRFTXXXXXXXXXRSDEADTLCMSAERNCTAEEFRCNNNKCIAKAWRXXXXXXX 11334
RCIP + +SDE C S R C +F+C N +CI ++W+
Sbjct: 3149 NKRCIPESWQCDGEDDCGDQSDEDPAHCSS--RTCRPGQFKCRNGRCIPQSWKCDVDNDC 3206
Query: 11335 XXXXXETPECAQIECKKGWTRCS--------SSYRCIPNWAFCNGQDDCRDNSDEDKQRC 11490
E E EC RC ++YRC+P W+ CNG +DCRD+SDE
Sbjct: 3207 GDNSDEPLE----ECMGPAYRCDNHTEFSCRTNYRCVPMWSVCNGHNDCRDDSDEQGCDE 3262
Query: 11491 PTCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKC 11670
TCD G+FRC + +CIP RW CD ++DCGDNSDE SC T R C+ESE+RC++ +C
Sbjct: 3263 LTCDPTGDFRC-NNHRCIPLRWRCDGDDDCGDNSDE--RSC--TPRTCTESEYRCDNLRC 3317
Query: 11671 IPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELH 11850
IP VCD C D DE C LR C PG+ QC G CI+E CD DC + DE
Sbjct: 3318 IPNRWVCDHDNDCEDNSDERDCELRTCHPGYFQCTSGHCISERFKCDGNPDCLDYTDETS 3377
Query: 11851 CED--VSRRTCSPFEFECANSVCIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRC 12024
C + C PF FEC N VC+ + SDE C QC+ P RFRC
Sbjct: 3378 CPTRFPNGTYCPPFMFECKNHVCVQPHWKCDGDDDCGDNSDEELHLCIDIQCETPFRFRC 3437
Query: 12025 AHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSFS---EYGDCSSDQFKCANGKCVNGT 12195
++R C+ +LCN NDCG D SDE C S +G C+ +++KC+NG C+
Sbjct: 3438 DNNR-CIYSHELCNSVNDCG--DGSDEIPENCERNSPNPTHGPCTDEEYKCSNGHCIPLP 3494
Query: 12196 VACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKHICTDVRD-GFYCHCRDGFRPDP 12372
ACD DDCGD SDE+GC + G +C ++ C+H CTD+R+ G C CR G++P
Sbjct: 3495 YACDDYDDCGDQSDELGCHR-GSTHTC----SDNICEHNCTDLREGGLLCSCRPGYKPRA 3549
Query: 12373 QSPKECIDIDECAGNNTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANV 12552
C D++EC TC Q C NTKGS+ C C + + V +G G +C A+G+ +
Sbjct: 3550 TEKHMCEDVNECEVYGTCPQECKNTKGSFECFCAKGF---VSIGEPHGTECAAQGNPPVL 3606
Query: 12553 MIGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERTIYRSAI 12732
++ + + + +L ++ ++D +E +
Sbjct: 3607 LLPDNVRIRRFNLSS--------------------------QQYSDYVDNAEHIQALDYL 3640
Query: 12733 ANGNQSHEGQKLDVDFAAMGVVPTAIAVDY-------TTGNLFIAAVSENIENGLVTAR- 12888
EGQ L A M + + + Y G ++ + E G +
Sbjct: 3641 ----WDPEGQGLSKMSACMPLHRYRLGLSYCCFLYGCAAGVVYWTVLGRGSEFGSIKCAY 3696
Query: 12889 ----KKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGR-ICYSDAG 13053
S P+ + +V PDG I GR I ++D+G
Sbjct: 3697 MPTFNDYGSNPVKEVDLNLRYVSKPDG-----------------IALDWVGRHIYWTDSG 3739
Query: 13054 LHAKIECADMDGTHRQIIVKDLVFSPTSMA------------------------------ 13143
+ +IE A +DG +R+ ++ + P ++A
Sbjct: 3740 TN-RIEVAKLDGRYRKWLIHTDLDQPAAIAVNPLLRMMYWTDWGRKPRIETAWMDGQNRA 3798
Query: 13144 --IDEGKG------------NRIYWVDPKYRRVDAVNIDGSERTTVV------------- 13242
+DE G NRIYW D K V+++ DG++R V+
Sbjct: 3799 VLVDEDLGWPTGLTVDYLNGNRIYWCDSKENTVESMKPDGTDRKAVISGGQSSALSGFSK 3858
Query: 13243 --------------HDRHIPYAVDVFENHIYWLSRESKTLYVQDKFGRG-RVSVLASDLE 13377
D PY++DVFE H+YW ++++ ++ +KFG G +V VL +
Sbjct: 3859 LQKETPHMHLVSTFSDIGHPYSLDVFEGHLYWTTKDTGEVWRTNKFGNGHKVKVLT--IN 3916
Query: 13378 DGHT-VRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTGFACLCPDG--IVPQLDGSCAT 13548
T VRV Q++ + Q + C+ CSHLC+ P G+ C CP G G C
Sbjct: 3917 PWLTQVRVYQEH-RHNQTVPNPCKNV-CSHLCLLRPG-GYTCACPQGSSFAESDFGICDA 3973
Query: 13549 QHVEALTMPKQCKCTNGGKCRLD----GSCECTSDFEGDQCEKESSVSRKIIGTLSENFI 13716
+TMP C+C NGG C D C+C + G C+ KII + +
Sbjct: 3974 AIEPPVTMPPACRCMNGGTCYTDEGGMPKCKCPYGYTGSYCD-----MGKIINAPAGTAV 4028
Query: 13717 TVXXXXXXXXXXXXXXXXXXXNLYKRR-------------QLLFKKNEAADGSVSFH-GN 13854
V N YKR L K + +G V+FH G+
Sbjct: 4029 AVLLAAIIIIITGALAAGVFLN-YKRTGSFIPSMPKLPSLSSLVKSADTGNG-VTFHSGD 4086
Query: 13855 VISFSNPVLENKQDAPGSEFNMQQMTSMHDDSTTFTNPVYELEDVDMSSPPPSNDQPSTS 14034
+ + + + + TF NP+Y ++P SND
Sbjct: 4087 NVDLGPSHIGVSFIDTAMQMDNNFAMEVGRQPITFENPLY------ATAPAASNDPAVIH 4140
Query: 14035 ASAMSPNRPSTSAASSFVPPTFDQDEIELKTADEIIVPKAEISKP 14169
A+ ++ N ++FV PT+ D+ II + SKP
Sbjct: 4141 ATQVTVNTSGEHLENNFVNPTYSGDQ-----RVSIITTSSSSSKP 4180
Score = 522 bits (1345), Expect = e-146
Identities = 417/1583 (26%), Positives = 674/1583 (42%), Gaps = 145/1583 (9%)
Frame = +1
Query: 1006 CSDINECAEFGYCDQLCANHRPGF-TCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADK 1182
C+D N G C+Q+C GF TC+C F L ++ + + Y V +
Sbjct: 1556 CTDNN----MGACEQICLPAPQGFFTCACATG-FKLNTDN---RTCAPYQSYVVISTLSA 1607
Query: 1183 MKLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVD 1362
+K F E + + V G ID I+W D FS+ V
Sbjct: 1608 IKGFSLEGED-------HSEAMVPVAGRGRNALHIDVHMASGFIYWCD------FSSTVA 1654
Query: 1363 DEGEISQIKK--LSLKSLVYP-------RCLAVDWITNTLYIIES--GSRRIDVSSYDGE 1509
+ + +IK L+S+V R +AVDW LY + ++V +
Sbjct: 1655 AQNGVRRIKPDGSGLRSIVTSGIGRNGIRGIAVDWAAGNLYFTNAFLTETYVEVLRLNTT 1714
Query: 1510 RRTVLLADGLTLPLDIALDPLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHTHQVSGI 1680
R VLL + +P I +DP R +F+ + K+E A +DGTNR LV++ G+
Sbjct: 1715 FRRVLLKTQVDMPRHIVVDPRRRYLFWADYGQHPKIERALLDGTNRTILVSSGIVTPRGL 1774
Query: 1681 VVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRL 1860
+D + VYWVD +D + + QG + +V G P P+G+ +F+ + W D
Sbjct: 1775 ALDWQSGYVYWVDDSLDMIARVSPQGGETEVVRYGSR-YPTPYGITVFENSIIWVDRNLK 1833
Query: 1861 GVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCT--NADC 2034
V + K T+ +N ++ + QP Q NPC N C
Sbjct: 1834 KVFRASKEPGSTEQPTVIRDNINMLRDVTIFDRHTQPTTAQELNF-----NPCVEENGGC 1888
Query: 2035 EGMCILSKDNGGFGVGYKCACPIGQKLVNGKRCIDS-IDYLLFSSNKIVRGIFPEINEKA 2211
C + G G C+C G + K C+ S DYL++++ VR + + ++ A
Sbjct: 1889 AHFCFALPEYGSDGQNKVCSCAFGNLGADNKGCVVSRDDYLIYTTESTVRSLRLDPDDHA 1948
Query: 2212 LAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAA-------- 2367
L P+ + + + + F D+ + IY + G GA+
Sbjct: 1949 LP---FPVVNVPRTSVALDF--------------DLTERRIYFTQSSGAGASKISYVSLS 1991
Query: 2368 -----PVLVTHNDGL-FSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLI 2529
PV+V + G +++DWI++++YY D + S+ + + E +R ++
Sbjct: 1992 APTSTPVVVAFDLGAPDGIAYDWINRRIYYSDFVNQSINSMSV---------EGSQRTVV 2042
Query: 2530 TELRDPVSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAEN 2709
+ P ++++ P +G +++ + A I R + G I N++L P+ + +D+ +
Sbjct: 2043 VHVSRPRAIMLDPCRGYMYWTDWGTHAKIERATLGGNFRTDIVNSSLVWPNGLTLDYEDE 2102
Query: 2710 RLCWGDTLLKTISCMDFDGKNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNG 2889
RL W D L+ I G + + P A+T+ +++IY+ SI R +K +G
Sbjct: 2103 RLYWADASLQKIERSSLTGSDREVIVSTAIYPFAMTMFDQFIYWTDWNTRSIYRANKHDG 2162
Query: 2890 GGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRA--SQCTQLCFATPSESHPNE 3063
G +++ + + A Q Q + PC+ C+ +C TP PN
Sbjct: 2163 SGQRVMIQNLPSRPMDIHVLASRKQQQ------CDSPCQQFNGGCSHIC--TPG---PNG 2211
Query: 3064 LEAKCACRQGFMINKENNHSCQKDPAEKIEQLCSSNSTQFQCKNGRCIPKEWKCDGENDC 3243
E C +G ++ H C D + + QF C NG CI +WKCD ENDC
Sbjct: 2212 AECHCP-SEGRWYLADSKH-CIPDNGTRCQ------PGQFTCMNGHCIRAQWKCDNENDC 2263
Query: 3244 LDESDEIDEK-GDK------CFHETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXX 3402
D SDE++ G K FH C C N +C+P
Sbjct: 2264 GDGSDELERVCGPKPKFTIVAFH--TCEPTVFTCGN-GRCVPYHYRCDHYDD-------- 2312
Query: 3403 VKYCKDGQ-------KPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNATC 3561
C D +P +++F C+N RCI + + + C TC
Sbjct: 2313 ---CGDNSDELGCLFRPCDPSREFTCNNGRCIAKDYVCNGINNCYDNGTSDEQNCPERTC 2369
Query: 3562 AANQFSC-ANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQCVPLRN 3738
Q C + CIP +LCDGDNDC D +DE C CS +FRC++GR C+P R
Sbjct: 2370 QPEQTKCQSTNICIPRSYLCDGDNDCGDMSDESPTHCVASTCSQSEFRCSSGR-CIPARW 2428
Query: 3739 HXXXXXXXXXXXXXXXXAV-TAESCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDE--- 3906
+ +C +QF+C G CI ++W SDE
Sbjct: 2429 YCDGGADCSDSSDEPLSCTPQVRTCNTEQFRC-DDGRCIASTWICDGDNDCGDMSDEDQR 2487
Query: 3907 ----------PKFGCTSG--------------------------------RQCSSDQFKC 3960
+F C + R C ++F C
Sbjct: 2488 HNCANRTCSNAEFTCVNNQPPQRKCIPRDWVCDGDADCADALDEHQNCTRRSCGVNEFTC 2547
Query: 3961 GNGRCILNNWLCDGENDCGDGSDES--SERGCK----TSMNARKCPFEHVACENDQET-- 4116
NG CI +++ CD NDCGDGSDE + + C+ T N R C C+ D +
Sbjct: 2548 SNGLCIRSSYRCDRRNDCGDGSDEQGCTYQACQQHQFTCQNGR-CISRDFVCDGDNDCGD 2606
Query: 4117 ---------------------------CIPLHQLCDGKTHCPGGTDEGGRCARDLCSADR 4215
CI L ++CD C +DE G +
Sbjct: 2607 ESDELEHMCHTPAPTCPPGEFRCDNGHCISLSRVCDRNDDCSDNSDEKGCGVNECTDPSI 2666
Query: 4216 AGCSFKCHNSPNGPICSCPFGEQLVNKTK-CEPENECLDSSS-CSQRCKDEKHGFTCSCD 4389
C C ++P IC+C G +L++ K C+ NEC ++ CSQ C++ + C C
Sbjct: 2667 HHCDHSCTDTPTSFICTCRPGYRLMSDGKTCDDVNECAETPRVCSQVCENTVGSYVCKCA 2726
Query: 4390 EGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGAIVE---NAIALAWD 4560
G+ + D +C+ ++ I+ SNR YY + + + I++ + +AL +D
Sbjct: 2727 PGFLREPDGHSCRQNSDIAPYLIF-SNR---YYLRNLSTDGAAYSLILQGLTSVVALDFD 2782
Query: 4561 SLTDRIYWSDIREKKILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVDSSLNTIE 4740
+ R+YW D+ + I + NG+N V + G+ EG+A+DW+ R LYWVDS + ++
Sbjct: 2783 RVDRRLYWIDVSRRVIERMSYNGSNREV-VVTGVLHGEGLAVDWIARKLYWVDSFSDCLK 2841
Query: 4741 VANLEDPKQRTLLVH----QNV---SQPRGIAVDPRKGVMFWTDWGQNPCIERASMDGTD 4899
V+ L+ + L H N PR I + P+ G ++WTDWG I R MDGT+
Sbjct: 2842 VSELDGRFVKKLAEHCVDANNTFCFENPRAIVLHPKYGFVYWTDWGDKAFIGRVGMDGTN 2901
Query: 4900 RQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHAL 5079
+ I+ TK+ WPN I +DYT D++Y++D+ L +I+F + DG R V + + HP AL
Sbjct: 2902 KAPIITTKLEWPNGITIDYTNDKLYWSDAHLSYIEFSDLDGQHRHTVYDGN--LPHPFAL 2959
Query: 5080 AIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCST 5259
+FED +Y++D + ++ KY +G+ + +T + + HP QP++ NPC+
Sbjct: 2960 TVFEDTVYWTDWNTRTVEKGNKY-DGSGRQALVNTTHRPFDIHVCHPYRQPIV-TNPCAV 3017
Query: 5260 N--PCSHLCLL-NNKNTFTCKCP 5319
N CSHLCL+ + TC+CP
Sbjct: 3018 NNGGCSHLCLIRHGGQEHTCECP 3040
Score = 416 bits (1068), Expect = e-113
Identities = 285/1019 (27%), Positives = 458/1019 (43%), Gaps = 29/1019 (2%)
Frame = +1
Query: 145 ASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXX-----XXPHPGCKSDQWQCDTYT 309
A C N F C++ +C+ W HPG Q+QC +
Sbjct: 638 APGTCPANQFTCSNHRCVPHSWRCDTDNDCGDGSDEADCQLGSTCHPG----QFQCPDHR 693
Query: 310 WHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKY 489
CI CD DC DG+DE+ C +C++ N F CA G QC + +CDG +
Sbjct: 694 -----CIDPSYVCDGDRDCVDGADERGC---IYNCTA-NEFKCASGHQCINGYYRCDGVF 744
Query: 490 DCRDLSDEKDSCSRNHTACF-QYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKK 666
DC D SDE+ +R C + +F+C CI +W CDG DC D SDE C +
Sbjct: 745 DCTDRSDERACPTRPPGMCHHESEFQCQSDGTCIPSTWECDGHPDCEDSSDEHHACPPRT 804
Query: 667 CTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDEC--GEYRCPPGKWNCPGTGHCIDQLK 840
C + F+C N C R + CD +DC D SDE +C +RCP +W CPG CI+
Sbjct: 805 CPSTFFRCDNGNCVLRSWICDGDNDCRDMSDERDCPTPPFRCPSWQWQCPGHSVCINLTT 864
Query: 841 LCDGSKDCADGADEQQ-CSQNLCP--SLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCS 1011
+CD + DC +GADE C+Q C + GC GC P G +CTCP GY+L + +TC
Sbjct: 865 VCDNTPDCPNGADESPLCNQESCSDNNAGCTHGCIQGPFGAQCTCPVGYQLSND-SKTCG 923
Query: 1012 DINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKL 1191
D++EC+ G C Q C N R F C C D + L+ + + C ++ + L
Sbjct: 924 DVDECSPPGICSQHCFNERGSFRCHC-QDGYALEAD----------QRTCKVSDLRQAFL 972
Query: 1192 FVARREGLYRLNPKNPDEEVKKLA-SGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDE 1368
VA R + + + + V L G I +DFD +++W+D +SA +
Sbjct: 973 LVASRNQIVQDDITSQPNVVHSLVRDGRNIVALDFDSVTDRVYWSDTSQDRIWSASNNG- 1031
Query: 1369 GEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLP 1548
S + + LAVDW+ LY + ++VS DG RTVL+++ +T P
Sbjct: 1032 ---SDRTVIFDSGVTVTESLAVDWVGRNLYWTDYVLETVEVSKLDGTHRTVLVSENVTNP 1088
Query: 1549 LDIALDPLRGE--MFFTN---QLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYW 1713
+ LDP MF+T+ ++E A+MDG R +VN+ + +G+ +D +Y+
Sbjct: 1089 RGLVLDPRSSAHLMFWTDWGRNPRIERASMDGKLRTVIVNSKLYWPNGLTIDYPNNLLYF 1148
Query: 1714 VDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKF-GS 1890
D +D ++ DY GN+R+ V V+ HP + +F+ ++YWTD V++ K+ G
Sbjct: 1149 ADAYLDFIDYCDYNGNNRKQVLASDLVLQHPHAITIFEDFVYWTDRYINRVMRAHKWHGE 1208
Query: 1891 DTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGG 2070
+ ++ N PMG+ A HP QP G N C + C +C+LS
Sbjct: 1209 NQTVMLFNLPQ---PMGLVAVHPARQPAGG----------NSCLRSPCSHICLLSAVGPA 1255
Query: 2071 FGVGYKCACPIGQKLVNGKRCIDSID--YLLFSSNKIVRGIFPEINEKALAEAVLPISPI 2244
+ Y CACP G L + ++ +L+ + I+ GI +K+ +A++P++ +
Sbjct: 1256 Y---YSCACPSGWTLAADQITCTRVEDPFLVVVRDSIIYGISLNPEDKS-NDAMVPVAGL 1311
Query: 2245 SQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGA---APVLVTHNDGLFSMSFD 2415
++V+ D + ++ + I+ ++ DG AP + + ++ D
Sbjct: 1312 QNG-----YDVDFDDNEQIIYWVE-HPGEIHSVKSDGTNRTEFAPAAILGSP--VGLALD 1363
Query: 2416 WISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKGLLFY-- 2589
WI++ LYY + S+EV+K+ + T PV + V P +G L++
Sbjct: 1364 WITQNLYYTNPSTQSIEVLKLRGEVQYRKTLITNNGSPTGAGSPVGIAVDPARGKLYWTD 1423
Query: 2590 --AEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFD 2763
E+ PA + ++DG N + L + +D EN+L W T I D D
Sbjct: 1424 QGTESGIPAKVASANMDGSNPVNLFTNNLDHIEFLTVDIRENKLYWAVTSTGAIESGDPD 1483
Query: 2764 GKNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVRE--FGADERSI 2937
G N + + P + + ++Y+ + I RV K G ++R+ G +
Sbjct: 1484 GTNRITIVTGLSHPWGVAVYGSHLYFTDRDFEVIERVDKTTGTNRVVLRDNVSGLRVLKV 1543
Query: 2938 FSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINKEN 3114
+ + + D++ C Q+C P CAC GF +N +N
Sbjct: 1544 HYRETSAGVSNGCTDNN------MGACEQICLPAPQGFF------TCACATGFKLNTDN 1590
Score = 297 bits (760), Expect = 6e-78
Identities = 208/688 (30%), Positives = 303/688 (43%), Gaps = 37/688 (5%)
Frame = +1
Query: 148 SSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPG---CKSDQWQCDTYTWHS 318
+S C++++FRC+ G+CI W P C ++Q++CD
Sbjct: 2408 ASTCSQSEFRCSSGRCIPARWYCDGGADCSDSSDEPLSCTPQVRTCNTEQFRCD-----D 2462
Query: 319 VSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADG----RQCFDVSKKCDGK 486
CIA CD DC D SDE S F C + R+C CDG
Sbjct: 2463 GRCIASTWICDGDNDCGDMSDEDQRHNCANRTCSNAEFTCVNNQPPQRKCIPRDWVCDGD 2522
Query: 487 YDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKK 666
DC D DE +C+R +C +F C++ CI+ S+ CD DC DGSDE C ++
Sbjct: 2523 ADCADALDEHQNCTRR--SCGVNEFTCSNGL-CIRSSYRCDRRNDCGDGSDEQG-CTYQA 2578
Query: 667 CTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDE----CGEYRCPPGKWNCPGTGHCIDQ 834
C ++F C+N RC R F CD +DCGD SDE E CPPG++ C GHCI
Sbjct: 2579 CQQHQFTCQNGRCISRDFVCDGDNDCGDESDELEHMCHTPAPTCPPGEFRCDN-GHCISL 2637
Query: 835 LKLCDGSKDCADGADEQQCSQNLC--PSLG-CQAGCHPSPHGGECTCPSGYKLDDRFHRT 1005
++CD + DC+D +DE+ C N C PS+ C C +P CTC GY+L +T
Sbjct: 2638 SRVCDRNDDCSDNSDEKGCGVNECTDPSIHHCDHSCTDTPTSFICTCRPGYRLMSD-GKT 2696
Query: 1006 CSDINECAEFG-YCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADK 1182
C D+NECAE C Q+C N + C C F + + + N + Y + +N
Sbjct: 2697 CDDVNECAETPRVCSQVCENTVGSYVCKCAPG-FLREPDGHSCRQNSDIAPYLIFSNR-- 2753
Query: 1183 MKLFVARREGLYRLNPKNPDEEVKKLASG-EFIYGIDFDYGDRKIFWTD-------RLAH 1338
Y N + G + +DFD DR+++W D R+++
Sbjct: 2754 ----------YYLRNLSTDGAAYSLILQGLTSVVALDFDRVDRRLYWIDVSRRVIERMSY 2803
Query: 1339 SAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRT 1518
+ + +V G +++ LAVDWI LY ++S S + VS DG R
Sbjct: 2804 NGSNREVVVTG------------VLHGEGLAVDWIARKLYWVDSFSDCLKVSELDG-RFV 2850
Query: 1519 VLLADGLT---------LPLDIALDPLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHT 1662
LA+ P I L P G +++T+ + + MDGTN+ ++ T
Sbjct: 2851 KKLAEHCVDANNTFCFENPRAIVLHPKYGFVYWTDWGDKAFIGRVGMDGTNKAPIITTKL 2910
Query: 1663 HQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYW 1842
+GI +D T ++YW D + +E D G R V G +PHPF L +F+ +YW
Sbjct: 2911 EWPNGITIDYTNDKLYWSDAHLSYIEFSDLDGQHRHTVYDGN--LPHPFALTVFEDTVYW 2968
Query: 1843 TDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPC- 2019
TDW V + K+ + NT + P I HP QP + NPC
Sbjct: 2969 TDWNTRTVEKGNKYDGSGRQALVNTTHR--PFDIHVCHPYRQP----------IVTNPCA 3016
Query: 2020 -TNADCEGMCILSKDNGGFGVGYKCACP 2100
N C +C++ G + C CP
Sbjct: 3017 VNNGGCSHLCLIRHG----GQEHTCECP 3040
Score = 247 bits (631), Expect = 5e-63
Identities = 222/820 (27%), Positives = 325/820 (39%), Gaps = 166/820 (20%)
Frame = +1
Query: 145 ASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHS-- 318
+S C F+C +G+CI W P C ++CD +T S
Sbjct: 3177 SSRTCRPGQFKCRNGRCIPQSW---KCDVDNDCGDNSDEPLEECMGPAYRCDNHTEFSCR 3233
Query: 319 --VSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYD 492
C+ + C+ DC D SDE+ C T C F C + +C + +CDG D
Sbjct: 3234 TNYRCVPMWSVCNGHNDCRDDSDEQGCDELT--CDPTGDFRC-NNHRCIPLRWRCDGDDD 3290
Query: 493 CRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCT 672
C D SDE+ R C + ++RC D +CI WVCD DC D SDE D CE + C
Sbjct: 3291 CGDNSDERSCTPR---TCTESEYRC-DNLRCIPNRWVCDHDNDCEDNSDERD-CELRTCH 3345
Query: 673 ANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDEC------GEYRCPPGKWNCPGTGHCIDQ 834
FQC + C +F+CD DC D +DE C G Y CPP + C C+
Sbjct: 3346 PGYFQCTSGHCISERFKCDGNPDCLDYTDETSCPTRFPNGTY-CPPFMFECK-NHVCVQP 3403
Query: 835 LKLCDGSKDCADGADEQ-------QC---------------SQNLCPSLG-CQAGC---- 933
CDG DC D +DE+ QC S LC S+ C G
Sbjct: 3404 HWKCDGDDDCGDNSDEELHLCIDIQCETPFRFRCDNNRCIYSHELCNSVNDCGDGSDEIP 3463
Query: 934 ------HPSPHGGECT-----CPSG------YKLDD-----------RFHR----TCSD- 1014
P+P G CT C +G Y DD HR TCSD
Sbjct: 3464 ENCERNSPNPTHGPCTDEEYKCSNGHCIPLPYACDDYDDCGDQSDELGCHRGSTHTCSDN 3523
Query: 1015 ----------------------------------INECAEFGYCDQLCANHRPGFTCSCL 1092
+NEC +G C Q C N + F C C
Sbjct: 3524 ICEHNCTDLREGGLLCSCRPGYKPRATEKHMCEDVNECEVYGTCPQECKNTKGSFECFCA 3583
Query: 1093 GDCFTLQMEHGPG------------KDNLTMRGYCVS--------NNADKMK----LFVA 1200
++ HG DN+ +R + +S +NA+ ++ L+
Sbjct: 3584 KGFVSIGEPHGTECAAQGNPPVLLLPDNVRIRRFNLSSQQYSDYVDNAEHIQALDYLWDP 3643
Query: 1201 RREGLYRLNPKNPDEEVK-KLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSA-------D 1356
+GL +++ P + L+ F+YG ++WT S F +
Sbjct: 3644 EGQGLSKMSACMPLHRYRLGLSYCCFLYGC----AAGVVYWTVLGRGSEFGSIKCAYMPT 3699
Query: 1357 VDDEGEISQIKK--LSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLA 1530
+D G + +K+ L+L+ + P +A+DW+ +Y +SG+ RI+V+ DG R L+
Sbjct: 3700 FNDYGS-NPVKEVDLNLRYVSKPDGIALDWVGRHIYWTDSGTNRIEVAKLDGRYRKWLIH 3758
Query: 1531 DGLTLPLDIALDPLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHTHQVSGIVVD-ITA 1698
L P IA++PL M++T+ + ++E A MDG NR LV+ +G+ VD +
Sbjct: 3759 TDLDQPAAIAVNPLLRMMYWTDWGRKPRIETAWMDGQNRAVLVDEDLGWPTGLTVDYLNG 3818
Query: 1699 KRVYWVDPKVDRLESIDYQGNDRRIVAQG------------------------MNVVPHP 1806
R+YW D K + +ES+ G DR+ V G + + HP
Sbjct: 3819 NRIYWCDSKENTVESMKPDGTDRKAVISGGQSSALSGFSKLQKETPHMHLVSTFSDIGHP 3878
Query: 1807 FGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQS 1986
+ L +F+ +LYWT V + KFG+ K+ + + + H Q P
Sbjct: 3879 YSLDVFEGHLYWTTKDTGEVWRTNKFGNGHKVKVLTINPWLTQVRVYQEHRHNQTVP--- 3935
Query: 1987 ECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIG 2106
NPC N C +C+L GY CACP G
Sbjct: 3936 --------NPCKNV-CSHLCLLRPG------GYTCACPQG 3960
Score = 235 bits (599), Expect = 3e-59
Identities = 172/596 (28%), Positives = 287/596 (47%), Gaps = 20/596 (3%)
Frame = +1
Query: 4603 KILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLV 4782
++ S + +G+N V + +D E +A+DWV LY V++S+N I+V + D R L+
Sbjct: 1 QVFSVDMDGSNVQVVLNVSVDYPENLAVDWVNNKLYVVEASVNRIDVVDF-DGSNRVTLI 59
Query: 4783 HQNVSQPRGIAVDPRKGVMFWTDW----GQNPCIERASMDGTDRQIIVKTKIYWPNTIAL 4950
+N+ PRG+AVDP G MF+TDW GQ P +ERA MDGT+R I+ TK+ WP+ I L
Sbjct: 60 TENLGNPRGVAVDPTVGYMFFTDWEAINGQ-PGLERAFMDGTNRYGIIGTKLGWPSGITL 118
Query: 4951 DYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKL 5130
D R+Y+ DS+ D+I+ YDG R V+ V HP +++FE +Y++D +
Sbjct: 119 DIEAKRIYWVDSRYDYIETATYDGVHRKTVVHGGAVVPHPFGISLFEHSVYFTDWTKMAV 178
Query: 5131 QVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTN--PCSHLCLLNNKNT- 5301
K+ T S PS NPC TN C H+C+L++++
Sbjct: 179 MRANKF---TDSSPPS--------------------VQNPCGTNRGGCEHICVLSHQSDN 215
Query: 5302 ----FTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNVFGIEMNSASEKETPVLAGMVPL 5469
+ CKC MG L A GK C + FL+ + V GI N +S+++ ++P+
Sbjct: 216 GGLGYRCKCRMGYDLHADGKHCF-AVRHFLLFSSQLAVRGIPFNLSSQEDI-----ILPV 269
Query: 5470 SGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNGGNKTKMFSSAVPDD 5649
+G + F + +++ T AK + I++ V+G + + ++ V D
Sbjct: 270 TGSPSYFIGVDFSAEDDVIFFSDT--AKDM--------IFKQKVDGTGREVLTANRV-DG 318
Query: 5650 AYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVI--LSNDQSXXXXXXXXXXXXXXX 5823
L +DW +NL + ++I +++ K R+++ L+N ++
Sbjct: 319 VEDLAYDWISKNLYWTDPRYRSISVMKVADKSRRAIVRNLNNPRAIVVHPLI-------- 370
Query: 5824 KGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAIDTTNTRVYFSEAKAGR 6003
GY+FW D AK+ RA DGS+ L I + L + +AID R+Y+ +A +
Sbjct: 371 -GYIFWTD---WYRPAKIMRAWGDGSHALSIVNTTLGWPNGLAIDWNAMRLYWVDAFFDK 426
Query: 6004 ISSVTYDGQDRHYVLSDGGRQ---PNGLAFYGDRLFYADSAFDSI-EVATINGDSQPPQW 6171
I +DGQ+R + D Q P GL + +Y D I V +G +
Sbjct: 427 IEHSNFDGQNR--ISLDRITQISHPFGLTIFEGYAYYTDWRLGGIVRVRKTDGG----EM 480
Query: 6172 THFKKDVENLANIKALQPRASSSGHPCH---INNGNCDHICIPLMFAQRTCTCANG 6330
++ + ++ ++K+ + + + C+ NG+C H C P+ +QR C C G
Sbjct: 481 VIIRRGISHIMHVKSFSSTSQTGFNLCNRLTNPNGDCSHFCFPVPDSQRVCGCPYG 536
Score = 157 bits (397), Expect = 7e-36
Identities = 108/353 (30%), Positives = 138/353 (38%), Gaps = 38/353 (10%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQ---------------W 291
C F+CNDG C PH C S Q
Sbjct: 3099 CRLGQFQCNDGNC--------------------TSPHLLCNSHQDCHDGSDEDPVLCATH 3138
Query: 292 QCDTYTWHSVS--CIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDV 465
QC+ + W + CI E +CD DC D SDE S+ C F C +GR C
Sbjct: 3139 QCENHQWQCANKRCIPESWQCDGEDDCGDQSDEDPAHCSSRTC-RPGQFKCRNGR-CIPQ 3196
Query: 466 SKKCDGKYDCRDLSDEK-DSCSRNHTACFQY-QFRCADKTQCIQKSWVCDGSKDCADGSD 639
S KCD DC D SDE + C C + +F C +C+ VC+G DC D SD
Sbjct: 3197 SWKCDVDNDCGDNSDEPLEECMGPAYRCDNHTEFSCRTNYRCVPMWSVCNGHNDCRDDSD 3256
Query: 640 EPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTG 819
E E +F+C N RC P ++RCD DDCGDNSDE C C ++ C
Sbjct: 3257 EQGCDELTCDPTGDFRCNNHRCIPLRWRCDGDDDCGDNSDERSCTPRTCTESEYRCDNL- 3315
Query: 820 HCIDQLKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFH 999
CI +CD DC D +DE+ C C H G C SG+ + +RF
Sbjct: 3316 RCIPNRWVCDHDNDCEDNSDERDCELRTC-------------HPGYFQCTSGHCISERF- 3361
Query: 1000 RTCSDINECAEF-------------GYCDQL---CANH---RPGFTCSCLGDC 1101
C +C ++ YC C NH +P + C DC
Sbjct: 3362 -KCDGNPDCLDYTDETSCPTRFPNGTYCPPFMFECKNHVCVQPHWKCDGDDDC 3413
Score = 154 bits (390), Expect = 5e-35
Identities = 106/293 (36%), Positives = 142/293 (48%), Gaps = 15/293 (5%)
Frame = +1
Query: 268 PGCKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDE-KDCPASTVDCSSQNVFMCAD 444
P C S Q++C ++ CI + +CD DC DGSDE CP V F C D
Sbjct: 3056 PMCTSTQYRCA----NNERCIPIWWKCDGQRDCRDGSDEPSTCP---VRHCRLGQFQCND 3108
Query: 445 GRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDC 624
G C C+ DC D SDE H C +Q++CA+K +CI +SW CDG DC
Sbjct: 3109 G-NCTSPHLLCNSHQDCHDGSDEDPVLCATH-QCENHQWQCANK-RCIPESWQCDGEDDC 3165
Query: 625 ADGSDE-PDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDE--DEC--GEYRCP 789
D SDE P C + C +F+C+N RC P+ ++CD +DCGDNSDE +EC YRC
Sbjct: 3166 GDQSDEDPAHCSSRTCRPGQFKCRNGRCIPQSWKCDVDNDCGDNSDEPLEECMGPAYRCD 3225
Query: 790 -PGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLG---C-QAGCHPSPH-- 948
+++C C+ +C+G DC D +DEQ C + C G C C P
Sbjct: 3226 NHTEFSCRTNYRCVPMWSVCNGHNDCRDDSDEQGCDELTCDPTGDFRCNNHRCIPLRWRC 3285
Query: 949 GGECTCPSGYKLDDRFHRTCSDINECAEFGY-CDQL-CANHRPGFTCSCLGDC 1101
G+ C D+ R+C+ C E Y CD L C +R + C DC
Sbjct: 3286 DGDDDCG-----DNSDERSCTP-RTCTESEYRCDNLRCIPNR--WVCDHDNDC 3330
Score = 144 bits (362), Expect = 8e-32
Identities = 113/399 (28%), Positives = 157/399 (39%), Gaps = 64/399 (16%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXX---PHPGCKSDQWQ-CD--TYTWHS 318
C F C +G CIR +W P P + C+ +T +
Sbjct: 2238 CQPGQFTCMNGHCIRAQWKCDNENDCGDGSDELERVCGPKPKFTIVAFHTCEPTVFTCGN 2297
Query: 319 VSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGR------------QCFD 462
C+ + RCD+ DC D SDE C D S + F C +GR C+D
Sbjct: 2298 GRCVPYHYRCDHYDDCGDNSDELGCLFRPCDPSRE--FTCNNGRCIAKDYVCNGINNCYD 2355
Query: 463 -----------------------------VSKKCDGKYDCRDLSDEKDSCSRNHTACFQY 555
S CDG DC D+SDE + T C Q
Sbjct: 2356 NGTSDEQNCPERTCQPEQTKCQSTNICIPRSYLCDGDNDCGDMSDESPTHCVAST-CSQS 2414
Query: 556 QFRCADKTQCIQKSWVCDGSKDCADGSDEPDTC--EFKKCTANEFQCKNKRCQPRKFRCD 729
+FRC+ +CI W CDG DC+D SDEP +C + + C +F+C + RC + CD
Sbjct: 2415 EFRCS-SGRCIPARWYCDGGADCSDSSDEPLSCTPQVRTCNTEQFRCDDGRCIASTWICD 2473
Query: 730 YYDDCGDNSDEDE---CGEYRCPPGKWNC----PGTGHCIDQLKLCDGSKDCADGADE-Q 885
+DCGD SDED+ C C ++ C P CI + +CDG DCAD DE Q
Sbjct: 2474 GDNDCGDMSDEDQRHNCANRTCSNAEFTCVNNQPPQRKCIPRDWVCDGDADCADALDEHQ 2533
Query: 886 QCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECA----EFGYCDQL 1053
C++ C E TC +G + + C N+C E G Q
Sbjct: 2534 NCTRRSCGV-------------NEFTCSNGLCIRSSYR--CDRRNDCGDGSDEQGCTYQA 2578
Query: 1054 CANHRPGFTCS---CLGDCFTLQMEHGPGKDNLTMRGYC 1161
C H+ FTC C+ F ++ G ++ + C
Sbjct: 2579 CQQHQ--FTCQNGRCISRDFVCDGDNDCGDESDELEHMC 2615
Score = 130 bits (328), Expect = 7e-28
Identities = 135/592 (22%), Positives = 234/592 (38%), Gaps = 13/592 (2%)
Frame = +1
Query: 5584 IYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVIL 5763
++ ++G N + + +V D L DW L V I+++ G ++I
Sbjct: 2 VFSVDMDGSNVQVVLNVSV-DYPENLAVDWVNNKLYVVEASVNRIDVVDFDGSNRVTLIT 60
Query: 5764 SNDQSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELD 5943
N GY+F+ D + RA +DG+N I L
Sbjct: 61 EN------LGNPRGVAVDPTVGYMFFTDWEAINGQPGLERAFMDGTNRYGIIGTKLGWPS 114
Query: 5944 HIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPN--GLAFYGDRLFYADSA 6117
I +D R+Y+ +++ I + TYDG R V+ G P+ G++ + +++ D
Sbjct: 115 GITLDIEAKRIYWVDSRYDYIETATYDGVHRKTVVHGGAVVPHPFGISLFEHSVYFTDWT 174
Query: 6118 FDSIEVATINGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHINNGNCDHICIPLM 6297
++ A DS PP V+N PC N G C+HIC+
Sbjct: 175 KMAVMRANKFTDSSPPS-------VQN----------------PCGTNRGGCEHICVLSH 211
Query: 6298 FAQR-----TCTCANGYVKDGQTSCKLFDESFVIVATKTKVIGYPIDETQSKGVAMEPIG 6462
+ C C GY F++ +++ V G P + + + + + G
Sbjct: 212 QSDNGGLGYRCKCRMGYDLHADGKHCFAVRHFLLFSSQLAVRGIPFNLSSQEDIILPVTG 271
Query: 6463 GLS-ITGVDYDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWI 6639
S GVD+ E I+ ++ + I + + + + + ++ LA DWI
Sbjct: 272 SPSYFIGVDFSAEDDVIFFSDTA--KDMIFKQKVDGTGREVLTANRVDG--VEDLAYDWI 327
Query: 6640 NYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTI 6819
+ N+Y+ D +I V K+ R+ ++ P +I V P+ Y++W D + I
Sbjct: 328 SKNLYWT--DPRYRSISVMKVADKSRRAIVRN-LNNPRAIVVHPLIGYIFWTDWYRPAKI 384
Query: 6820 QRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTG-GTPELVR-S 6993
R++ DGS IV++ + P L +D + +YW DA D I G L R +
Sbjct: 385 MRAWGDGSHALSIVNTTLGWPNGLAIDWNAMRLYWVDAFFDKIEHSNFDGQNRISLDRIT 444
Query: 6994 DIASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSN 7173
I+ G+ + Y+TD RL + R ++ + + I V FSS
Sbjct: 445 QISHPFGLTIFEGYAYYTDWRLGGIVRVRKTDGGEMVI-----IRRGISHIMHVKSFSST 499
Query: 7174 NQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCARGVL---KGRTCEE 7320
+Q + ++T+ C+ CF P +Q C C G+ RTC E
Sbjct: 500 SQTGFNLCNRLTN--PNGDCSHFCFPVPDSQR-VCGCPYGMKLLPNQRTCVE 548
Score = 107 bits (268), Expect = 7e-21
Identities = 57/147 (38%), Positives = 70/147 (46%), Gaps = 12/147 (8%)
Frame = +1
Query: 502 LSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTC--------- 654
L+D K N T C QF C + CI+ W CD DC DGSDE +
Sbjct: 2224 LADSKHCIPDNGTRCQPGQFTCMNG-HCIRAQWKCDNENDCGDGSDELERVCGPKPKFTI 2282
Query: 655 -EFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCID 831
F C F C N RC P +RCD+YDDCGDNSDE C C P + G CI
Sbjct: 2283 VAFHTCEPTVFTCGNGRCVPYHYRCDHYDDCGDNSDELGCLFRPCDPSREFTCNNGRCIA 2342
Query: 832 QLKLCDGSKDCADG--ADEQQCSQNLC 906
+ +C+G +C D +DEQ C + C
Sbjct: 2343 KDYVCNGINNCYDNGTSDEQNCPERTC 2369
Score = 103 bits (256), Expect = 2e-19
Identities = 79/245 (32%), Positives = 104/245 (42%), Gaps = 22/245 (8%)
Frame = +1
Query: 376 SDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDE---------KDSCS 528
+D K C F C +G C KCD + DC D SDE K +
Sbjct: 2225 ADSKHCIPDNGTRCQPGQFTCMNGH-CIRAQWKCDNENDCGDGSDELERVCGPKPKFTIV 2283
Query: 529 RNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCT-ANEFQCKNKRC 705
HT C F C + +C+ + CD DC D SDE C F+ C + EF C N RC
Sbjct: 2284 AFHT-CEPTVFTCGNG-RCVPYHYRCDHYDDCGDNSDELG-CLFRPCDPSREFTCNNGRC 2340
Query: 706 QPRKFRCDYYDDCGDN--SDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGAD 879
+ + C+ ++C DN SDE C E C P + C T CI + LCDG DC D +D
Sbjct: 2341 IAKDYVCNGINNCYDNGTSDEQNCPERTCQPEQTKCQSTNICIPRSYLCDGDNDCGDMSD 2400
Query: 880 EQ--QCSQNLC--PSLGCQAG-CHPS----PHGGECTCPSGYKLDDRFH-RTCSDINECA 1029
E C + C C +G C P+ G +C+ S L RTC+
Sbjct: 2401 ESPTHCVASTCSQSEFRCSSGRCIPARWYCDGGADCSDSSDEPLSCTPQVRTCNTEQFRC 2460
Query: 1030 EFGYC 1044
+ G C
Sbjct: 2461 DDGRC 2465
Score = 88.2 bits (217), Expect = 5e-15
Identities = 60/177 (33%), Positives = 75/177 (41%), Gaps = 11/177 (6%)
Frame = +1
Query: 628 DGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECG--EYRCPPGKW 801
D S+EP T + C AN F C N +C P +RCD DDC DNSDE +CG C P +
Sbjct: 549 DPSNEPPTLQ---CGANSFSCGNGKCVPNSYRCDGVDDCHDNSDEVDCGVNNSTCSPTAF 605
Query: 802 NCPGTGHCIDQLKLCDGSKDCADGADEQQC---SQNLCPSLGCQAGCHPS-PHGGEC--- 960
C T C+ CDG DC D +DE C + CP+ H PH C
Sbjct: 606 TCANT-RCVPAAWRCDGHNDCFDNSDESSCPAPAPGTCPANQFTCSNHRCVPHSWRCDTD 664
Query: 961 -TCPSGY-KLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHG 1125
C G + D + TC +F D C + P + C DC E G
Sbjct: 665 NDCGDGSDEADCQLGSTCHP----GQFQCPDHRCID--PSYVCDGDRDCVDGADERG 715
Score = 70.1 bits (170), Expect = 2e-09
Identities = 66/272 (24%), Positives = 108/272 (39%), Gaps = 9/272 (3%)
Frame = +1
Query: 2332 IYRIRPDGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDEL 2511
++ + DG VL D +++ DW++ +LY V+ N ++VV D
Sbjct: 2 VFSVDMDGSNVQVVLNVSVDYPENLAVDWVNNKLYVVEASVNRIDVVDF--------DGS 53
Query: 2512 VRRQLITE-LRDPVSVVVHPWKGLLFYA--EAMR-PAAIYRCHIDGQNCQVIRNTTLGRP 2679
R LITE L +P V V P G +F+ EA+ + R +DG N I T LG P
Sbjct: 54 NRVTLITENLGNPRGVAVDPTVGYMFFTDWEAINGQPGLERAFMDGTNRYGIIGTKLGWP 113
Query: 2680 SEMAIDFAENRLCWGDTLLKTISCMDFDG---KNVVKLDIDNPIPVAITIMNEYIYYVHQ 2850
S + +D R+ W D+ I +DG K VV P P I++ +Y+
Sbjct: 114 SGITLDIEAKRIYWVDSRYDYIETATYDGVHRKTVVHGGAVVPHPFGISLFEHSVYFTDW 173
Query: 2851 RPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQ--CTQ 3024
++ R +K V ++PC ++ C
Sbjct: 174 TKMAVMRANKFTDSSPPSV----------------------------QNPCGTNRGGCEH 205
Query: 3025 LCFATPSESHPNELEAKCACRQGFMINKENNH 3120
+C + +S L +C CR G+ ++ + H
Sbjct: 206 ICVLS-HQSDNGGLGYRCKCRMGYDLHADGKH 236
>gi|45382557|ref|NP_990573.1| low density lipoprotein-related protein 1;
alpha-2-macroglobulin receptor [Gallus gallus]
gi|1708864|sp|P98157|LRP1_CHICK Low-density lipoprotein
receptor-related protein 1 precursor (LRP)
(Alpha-2-macroglobulin receptor) (A2MR)
gi|1079416|pir||A53102 alpha-2-macroglobulin receptor precursor -
chicken
gi|438007|emb|CAA52870.1| alpha-2-macroglobulin receptor [Gallus
gallus]
Length = 4543
Score = 2076 bits (5378), Expect = 0.0
Identities = 1414/4513 (31%), Positives = 2139/4513 (47%), Gaps = 140/4513 (3%)
Frame = +1
Query: 544 CFQYQFRCADKTQCIQKSWVCDGSKDCADGSDE-PDTCEFKKCTANEFQCKNKRCQPRKF 720
C QF C D+ CI K W CDG KDC DGSDE PD C Q K RCQP +
Sbjct: 29 CSPKQFACKDQITCISKGWRCDGEKDCPDGSDESPDICP---------QSKVSRCQPNEH 79
Query: 721 RCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADE-QQCSQ 897
NC GT CI KLC+G DC DG+DE C +
Sbjct: 80 ---------------------------NCLGTELCIHMSKLCNGLHDCFDGSDEGPHCRE 112
Query: 898 NL--CPSLGCQAGCHPSPHGGECTCPSGYKL-DDRFHRTCSDINECAEFGYCDQLCANHR 1068
L C +LGCQ C P+ G C C + ++L +DR R+C D +EC +G C Q C N
Sbjct: 113 QLANCTALGCQHHCVPTLSGPACYCNNSFQLAEDR--RSCKDFDECTVYGTCSQTCTNTE 170
Query: 1069 PGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMK---LFVARREGLYRLNPKNP 1239
+TCSC+ + + LQ DN + C + N + L +A + +
Sbjct: 171 GSYTCSCV-EGYLLQ------PDNRS----CKAKNEPVDRPPVLLIANSQNILATYLSGA 219
Query: 1240 DEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIK--------KL 1395
S + +DF+Y + + W + SA S + +I +K +
Sbjct: 220 PVPNITPTSAKQTTAMDFNYIEDTVCWV-HVGDSA-SQTILKCAKIPNLKGFVEERSINI 277
Query: 1396 SLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLR 1575
SL SL +A+DW+T Y ++ RI V + +G LL L P IALDP
Sbjct: 278 SL-SLHQVEQMAIDWLTGNFYFVDDIDDRIFVCNKNGLTCVTLLDLELYNPKGIALDPAM 336
Query: 1576 GEMFFTNQ---LKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESI 1746
G++FFT+ K+E MDG NR LV++ GI +D+ ++ VYW D +D +E +
Sbjct: 337 GKVFFTDYGQIPKVERCDMDGQNRTKLVDSKIVFPHGITLDLVSRLVYWADAYLDYIEVV 396
Query: 1747 DYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTD------WTRLGVIQVEKFGSDTKLLW 1908
DY+G +R + QG+ ++ H +GL +F+ YLY T+ + VI+V +F S +
Sbjct: 397 DYEGKNRHTIIQGI-LIEHLYGLTVFENYLYATNSDNANAQQKTSVIRVNRFNSTEYQVV 455
Query: 1909 SNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYK 2088
+ + + YH QP C + P C +C+L G
Sbjct: 456 TRVDKG---GALHIYHQRRQPTVRSHACEPDQFGKP---GGCSDICLL----GNSHKSRT 505
Query: 2089 CACPIGQKL-VNGKRCIDSIDYLLFSSNK----IVRGIFPEINEKALAEAVLPISPISQR 2253
C C G L +GK C L K I+RG+ ++ K E ++PI +
Sbjct: 506 CRCRSGFSLGSDGKSCKKPEHELFLVYGKGRPGIIRGM--DMGAKVPDEHMIPIENLMNP 563
Query: 2254 RIGMYFEVECDVHGNS--FFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWISK 2427
R D H + ++AD I R + DG +L + ++ DW+
Sbjct: 564 R-------ALDFHAETGFIYFADTTSYLIGRQKIDGTERETILKDGIHNVEGIAVDWMGN 616
Query: 2428 QLYYVDN-IRNSLEVVKIGETGLVHPDELVRRQLIT-ELRDPVSVVVHPWKGLLFYAE-- 2595
LY+ D+ + ++ V ++ + R+ LI ++ P ++VV P G +++ +
Sbjct: 617 NLYWTDDGPKKTISVARLEKAA------QTRKTLIEGKMTHPRAIVVDPLNGWMYWTDWE 670
Query: 2596 ----AMRPAAIYRCHIDGQNCQV-IRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDF 2760
+ I R +DG N V I + T+ P+ +++D L W D I +
Sbjct: 671 EDPKDSKRGKIERAWMDGSNRNVFITSKTVLWPNGLSLDIPAKILYWVDAFYDRIEMVYL 730
Query: 2761 DG--KNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERS 2934
+G + +V + + + ++++ R SI R+ + SK V +
Sbjct: 731 NGTERKIVYEGPELNHAFGLCHYSSFLFWTEYRSGSIYRLDQ----SSKAVSLLRNERPP 786
Query: 2935 IFSLKACSHQNQPIPDDSREHPCRASQ--CTQLCFATPSESHPNELEAKCACRQGFMINK 3108
IF ++ Q Q + + CR + C+ LC ATP +CAC + ++
Sbjct: 787 IFEIRMYDAQQQQVGSNK----CRVNNGGCSSLCLATPR-------GRQCACAEDQILGA 835
Query: 3109 ENNHSCQKDPAEKIEQLCSSNSTQFQCKNGRCIPKEWKCDGENDCLDESDEIDEKGDKCF 3288
+ + +C+ +P+ C +F CKN RCI + WKCDG+NDCLD SDE E
Sbjct: 836 D-SVTCEANPSYIPPPQCQPG--EFACKNNRCIQERWKCDGDNDCLDNSDEAPE----LC 888
Query: 3289 HETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNH 3468
H+ C + KC+N +CIP + C C+ +F C +
Sbjct: 889 HQHTCPSDRFKCKN-NRCIPNRWLCDGDNDCGNNEDESNSTC---SARTCSPNQFSCASG 944
Query: 3469 RCIPEQWKXXXXXXXXXXXXEKLEMCGNATC-AANQFSCANGRCIPIYWLCDGDNDCYDG 3645
RCIP W E C TC QF+C NGRCI I W CD DNDC D
Sbjct: 945 RCIPISWTCDLDDDCGDRSDESAS-CAYPTCFPLTQFTCNNGRCININWRCDNDNDCGDN 1003
Query: 3646 TDEDKERCPPVQCSALQFRCANGRQCVPLR------NHXXXXXXXXXXXXXXXXAVTAES 3807
+DE C CS+ QF+C +GR C+P+ N
Sbjct: 1004 SDE--AGCSH-SCSSNQFKCNSGR-CIPVHWTCDGDNDCGDYSDETHANCTNQATRPPGG 1059
Query: 3808 CTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKCG---NGRCI 3978
C D+F+C GLCIP W+ SDE C K G + RCI
Sbjct: 1060 CHTDEFQCRLDGLCIPMRWRCDGDTDCMDSSDEK--NCEGVTHVCDPNVKFGCKDSARCI 1117
Query: 3979 LNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDGKTHC 4158
W+CDG++DC D SDE + C++ + C C N+ C+P +LCDG C
Sbjct: 1118 SKAWVCDGDSDCEDNSDEEN---CESLV----CKPPSHTCANNTSICLPPEKLCDGSDDC 1170
Query: 4159 PGGTDEGGRCARDLCSADRAGCSFKCHNSP-NGPICSCPFGEQL--VNKTKCEPENECLD 4329
G+DEG C D CS + GCS C +P G +CSCP G +L NKT C+ ++ C
Sbjct: 1171 GDGSDEGELC--DQCSLNNGGCSHNCTVAPGEGIVCSCPLGMELGADNKT-CQIQSYCAK 1227
Query: 4330 SSSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDN 4509
CSQ+C+ +K+ CSC EG+ L+ D +C+ D K I+ SNR+ I D +
Sbjct: 1228 HLKCSQKCEQDKYNVKCSCYEGWMLEPDGESCRSLDPFKPFIIF-SNRHEIRRIDLHRGD 1286
Query: 4510 WHTFGAIVENAIALAWDSLTDRIYWSDIREKKI----LSANRNGTNATVFIADGLDITEG 4677
+ + N IAL + +YW+D+ E KI L N T+ V I GL EG
Sbjct: 1287 YSVLVPGLRNTIALDFHLNQSSLYWTDVVEDKIYRGKLLENGALTSFEVVIQYGLATPEG 1346
Query: 4678 IALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWG 4857
+A+DW+ N+YWV+S+L+ IEVA L D RT L+ ++ PR IA+DPR G++FWTDW
Sbjct: 1347 LAVDWIAGNIYWVESNLDQIEVAKL-DGTMRTTLLAGDIEHPRAIALDPRYGILFWTDWD 1405
Query: 4858 QN-PCIERASMDGTDRQIIVKT--KIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSG 5028
+ P IE ASM G R+ I K WPN + +DY R+ + D++ D I YDG+G
Sbjct: 1406 ASLPRIEAASMSGAGRRTIHKETGSGGWPNGLTVDYLEKRILWIDARSDAIYSALYDGTG 1465
Query: 5029 RTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVV 5208
+VL +++ HP A+ ++ +Y++D R L K+ G T ++ +
Sbjct: 1466 HIEVLRGHEYLSHPFAVTLYGGEVYWTDWRTNTLAKANKW-TGHNVTVVQRTNTQPFDLQ 1524
Query: 5209 AVHPVLQPVIKNNPCSTN----PCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKPF 5376
HP QP + NPC N PCSHLCL+N T +C CP KLD C + K F
Sbjct: 1525 VYHPSRQP-LAPNPCEANGGKGPCSHLCLINYNRTLSCACPHLMKLDKDNTTCY-EFKKF 1582
Query: 5377 LVIIQKTNVFGIEMNSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKT 5556
L+ ++ + G+++++ +++ VP + N YDA+ + ++
Sbjct: 1583 LLYARQMEIRGVDIDNPYYNY--IISFTVP--DIDNVTVVDYDAVEQRIY---------- 1628
Query: 5557 LAQITTDSAIYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKIT--QTIEIIR 5730
+ + T + I R+ +NG + S+ +P +A+ L DW RNL + T + I + R
Sbjct: 1629 WSDVRTQT-IKRAFINGTGVETVVSADLP-NAHGLSVDWVSRNLFWTSYDTNKKQINVAR 1686
Query: 5731 TQGKQYRSVILSNDQSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPL 5910
G +VI D+ G ++W D ++ A +DGSN
Sbjct: 1687 LDGSFKNAVIQGLDKP-------HCLVVHPLHGKLYWTD------GDNISVANMDGSNRT 1733
Query: 5911 VIASNDLAELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGR--QPNGLAF 6084
++ +N + +AID +++Y+ + G I+ DG D +++ + + LA
Sbjct: 1734 LLFTNQRGPVG-LAIDYPESKLYWISSGNGTINRCNLDGSDLEVIVAVKSQLSKATALAI 1792
Query: 6085 YGDRLFYADSAFDSIEVATINGDSQPPQWTHFKKDVENLANIKALQPRASSSG-HPCHIN 6261
GD+L++AD A S + T N + T + + +K +G +PC +N
Sbjct: 1793 MGDKLWWADQA--SERMGTCN-KKDGTEVTVLRNSTTLVMLMKVYDESIQQAGSNPCSVN 1849
Query: 6262 NGNCDHICIPLMFAQRTCTCANGY-VKDGQTSCKLFDESFVIVATKTKVIGYPIDETQSK 6438
NG+C +C+P R+C C GY +K GQ SC+ SF++ + + G P+D K
Sbjct: 1850 NGDCSQLCLPTSETSRSCMCTAGYSLKSGQQSCEGVG-SFLLYSVHEGIRGIPLD-PNDK 1907
Query: 6439 GVAMEPIGGLSI-TGVDYDYESKTIYVAE--ASGINKGITAYTIGESSPRAVIRDSIGSL 6609
A+ P+ G S+ G+D+ E+ TIY + S I++ T E V+ + IG
Sbjct: 1908 SDALVPVSGTSLAVGIDFHAENDTIYWVDMGLSTISRAKRDQTWRED----VVTNGIG-- 1961
Query: 6610 TIKSLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLY 6789
++ +A+DWI N+Y+ + + IEV++L+G++R ++++ + P +I V P YL+
Sbjct: 1962 RVEGIAVDWIAGNIYWTDQGFD--VIEVARLNGSFRYVVISQGLDKPRAITVHPEKGYLF 2019
Query: 6790 WADQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRV-RST 6966
W + GQ P I+RS LDG+ R V+V+ I+ P + VD +YW DA+ D I R+ T
Sbjct: 2020 WTEWGQYPRIERSRLDGTERMVLVNVSISWPNGISVDYEDGKLYWCDARTDKIERIDLET 2079
Query: 6967 GGTPELV-RSDIASAAGVALHGQNMYWTD-NRLEKLFRATSKPNQTSLLLSPTTVAASLK 7140
G E+V SD V++ +YW+D + SK N T + T + LK
Sbjct: 2080 GENREVVLSSDNMDMFSVSVFEDYIYWSDRTHANGSIKRGSKDNATESVSLRTGIGVQLK 2139
Query: 7141 DIGDVAVFSSNNQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCARGVLK--GRTC 7314
DI VF+ Q + Q C QLC G + TC+CA G+L G +C
Sbjct: 2140 DI---KVFNRARQKGTNVCAQ-----NNGGCQQLCLFRGGGRR-TCACAHGMLSEDGVSC 2190
Query: 7315 EEPDTYIMFSDGDKIIDVAIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPV 7494
+ D Y+++S+ + + + + + P+K PF + +++ + +
Sbjct: 2191 RDYDGYLLYSERTILKSIHLSDENNLNAPIK-PFEDAEHMKNV-----IALAFDYRYGTK 2244
Query: 7495 GVNISWFSMNNAENPRLV--FGASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVM-- 7662
G N ++S + N + + G ++ + + + + +Y+T+ +
Sbjct: 2245 GSNRIFYSDIHFGNIQQINDDGTGRRTIVENVGSVEGLAYHRGWDTLYWTSYTTSTITRH 2304
Query: 7663 AIDTA------GEHLSTIASGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLA 7824
+D + E + T++ D A +D C L+FW T+ P I R+ L+
Sbjct: 2305 TVDQSRLGAFERETVITMSGDDHPRAFVLDECQNLMFW------TNWNEQHPSIMRATLS 2358
Query: 7825 GGSRKVIVSESISLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVI--ASGYRAKS 7998
G + +I+ + I P +A+D R +KIY++D IE +YDG +R VI +
Sbjct: 2359 GANVLIIIDQDIRTPNGLAIDHRAEKIYFSDATLDKIERCEYDGSHRHVILKSEPVHPFG 2418
Query: 7999 LDIWDRWLYMSDPLSNGVFRIDKESGSGLENV-VSDRRIPGALRVFASESDVRTRNQVCN 8175
L ++ +++ +D + V R +K G+ ++ + V + P + A+++D
Sbjct: 2419 LAVYGDYIFWTDWVRRAVQRANKYVGTDMKLLRVDIPQQPMGIIAVANDTD--------- 2469
Query: 8176 ALTSQLCKTDNGGCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSN 8355
+ C+ +NGGC LC + V CSC L ++ + N
Sbjct: 2470 SCELSPCRVNNGGCQDLCLLT------PKGHVNCSCRGERVLQED--------FTCKALN 2515
Query: 8356 SEPAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRR 8535
S C F+CG+G CI TCD C D SDE +YC++R C + + C N R
Sbjct: 2516 S----TCNVHDEFECGNGDCIDFSRTCDGVVHCKDKSDEKQSYCSSRKCKKGFLHCMNGR 2571
Query: 8536 CIDSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVS 8715
C+ S CN +DDCGD SDE+ C + +CA F C +G CI + C+ DC D S
Sbjct: 2572 CVASRFWCNGVDDCGDNSDEVPC-NKTSCAATEFRCRDGSCIGNSSRCNQFIDCED--AS 2628
Query: 8716 DESLATCPGLPIDCR-----GVK----VRCPNTNICIQPADLCDGYDDCGDKADE-NQLF 8865
DE T DC GVK +C +T++C P+ +CDG +DCGD +DE N
Sbjct: 2629 DEMNCTA----TDCSSYFKLGVKGTTFQKCEHTSLCYAPSWVCDGANDCGDYSDERNCPG 2684
Query: 8866 CMNQQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCD 9045
+C +Y CPSGRCIP TW CD ++DC +G DETH C++ K C F+C+
Sbjct: 2685 GRKPKCPANYFACPSGRCIPMTWTCDKEDDCENGEDETH--CSERQ-DKFCY-PVQFECN 2740
Query: 9046 NLKCISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWL 9225
N +CIS+ ++ SR C TC+ F C Y C+P WL
Sbjct: 2741 NHRCISKLWVCDGADDCGDGSDEDSR--CRLTTCSTGSFQCPGT-------YVCVPERWL 2791
Query: 9226 CDGDVTCAGGEDESTELCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANC 9405
CDGD CA G DE+ C++ EF C N+ CI + CD D+DC DGSDE C
Sbjct: 2792 CDGDKDCADGADETLAAGCLYNNTCDEREFMCGNRQCIPKHFVCDHDDDCGDGSDESPEC 2851
Query: 9406 TYSSCQPDFFQCANHKCVPNS-WKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQC 9582
Y +C P F+CAN +C+ NS W+CDG DC D SDE PKN + SKC++ F C
Sbjct: 2852 EYPTCGPHEFRCANGRCLSNSQWECDGEFDCHDHSDE--APKNPRCSSPESKCNDSFFMC 2909
Query: 9583 TSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEGF 9762
+G+CI +A +CD N DC D SDE + CFI+EC + C Q+C D+KIGYKC C GF
Sbjct: 2910 KNGKCIPEALLCDNNNDCADGSDELN-CFINECLNKKLSGCSQECEDLKIGYKCRCRPGF 2968
Query: 9763 AIDISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEP 9942
+ D K+C +++EC CSQKC + +GSYKC C++GY+L D+ + + + EP
Sbjct: 2969 RLK-DDGKTCIDIDEC-STTYPCSQKCINTLGSYKCLCIEGYKLKPDNPTSCKAVTDEEP 3026
Query: 9943 FFLLANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLID---QGKLRLLRVDL 10113
F + AN++Y+RK+++DG+ Y L QG +N V+LD D E+ Y D QG + +
Sbjct: 3027 FLIFANRYYLRKLNLDGSNYTLLKQGLNNAVALDFDYREQMIYWTDVTTQGSM------I 3080
Query: 10114 DEMDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDR 10293
M S+ + + R + +G+AVDWVG LY ++ +I V +L+G + L+
Sbjct: 3081 RRMHINGSNVQVLHRTGLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVNSG 3140
Query: 10294 IQQPKAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDY 10473
+++P+A+VV GYL++T+W IG+I +DG+ + + + WPN + +DY
Sbjct: 3141 LREPRALVVDVQNGYLYWTDWGDHSLIGKIGMDGTNR-----SVIVDTKITWPNGLTLDY 3195
Query: 10474 FSDRLFWGDAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCD 10653
+ R++W DA + I F DG+ R + +Q H+ ++ +F+DY+YW DW + + R
Sbjct: 3196 INSRIYWADAREDYIEFASLDGSNRHTVLSQDIPHIFALTLFEDYIYWTDWETKSINRAH 3255
Query: 10654 KWTGKNETILKKTVQLPNDLRIVHPMRQPAYPN-PCGDNNGGCSHLCLIGAGGNGYTCSC 10830
K TG N+T+L T+ P D+ I HP RQP PN PC NN GCS+LCL+ GG G+ C+C
Sbjct: 3256 KTTGANKTLLISTLHRPMDIHIYHPYRQPDVPNHPCKTNNAGCSNLCLLSPGG-GHKCAC 3314
Query: 10831 PDQFVLLSDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRI 11010
P F L SD KTC NCT QF C D KCIP W CD E DC D SDEP + C +
Sbjct: 3315 PTNFYLGSDGKTCVSNCTASQFVCKND--KCIPFWWKCDTEDDCGDRSDEPED--CPEFK 3370
Query: 11011 CPVGEFQCTNHNCTRPFQIXXXXXXXXXXXXEQNCD-KACDPWMFKCAATGRCIPRRFTX 11187
C G+FQC+ CT P I E NCD C P FKC T RCIP F
Sbjct: 3371 CRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCTNTNRCIPGIFRC 3430
Query: 11188 XXXXXXXXRSDEADTLCMSAERNCTAEEFRCN-NNKCIAKAWRXXXXXXXXXXXXETPEC 11364
DE D E C +F+C +CI + W E C
Sbjct: 3431 NGQDNCGDGEDEKD----CPEVTCAPNQFQCAITKRCIPRVWVCDRDNDCVDGSDEPANC 3486
Query: 11365 AQIECKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCP--TCDDVGEFRCATSGK 11538
Q+ C RC S RCIP C+G+DDC D SDE K+ C TC+ +FRC + +
Sbjct: 3487 TQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPY-QFRC-KNNR 3544
Query: 11539 CIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDG 11718
C+P RW CD +NDCGDNSDE SC T RPCSESEF C +G+CI G CDG C+DG
Sbjct: 3545 CVPGRWQCDYDNDCGDNSDE--ESC--TPRPCSESEFSCANGRCIAGRWKCDGDHDCADG 3600
Query: 11719 LDESQCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFEC 11898
DE C + RC QC +G CI CD DC + DE C RTC EF+C
Sbjct: 3601 SDEKDC-IPRCEFDQYQCKNGHCIPMRWRCDADADCMDGTDEEDC-GTGVRTCPLDEFQC 3658
Query: 11899 ANSVCIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFND 12078
N++ P + SDE EC QC P FRC + R+CL I + C+G ++
Sbjct: 3659 NNTLRKPLAWKCDGEDDCGDNSDENPEECLKFQCPPNRPFRCKNDRVCLWIGRQCDGIDN 3718
Query: 12079 CGPNDFSDEHLSMCSSFSEYGDCSSD--QFKCANGKCVNGTVACDRKDDCGDASDEIGCS 12252
CG N +DE S ++ CS D +F C N KC++ + C+ DDCGD SDE CS
Sbjct: 3719 CGDN--TDEK-DCESPTAKPKSCSQDKNEFLCENKKCISANLRCNFFDDCGDGSDEKSCS 3775
Query: 12253 KHGGKTSCEAFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQ 12432
C G + C + YC CR GF+ P C D++EC TC+Q
Sbjct: 3776 HEHKSYDCMTNTTMCGDEAQCIQAQSSTYCTCRRGFQKVPDK-NSCQDVNECLRFGTCSQ 3834
Query: 12433 LCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGSGTNR 12612
LC NTKGS++C C +++ T C+A+G ++ ADD+ ++ + +
Sbjct: 3835 LCNNTKGSHVCSCAKNF-------MKTDNMCKAEGSEHQILYIADDNKIRSMYPFNPNSA 3887
Query: 12613 HXXXXXXXXXXXXXXXXXXPRKELMYWIDG-----SERTIYRSAIANGNQSHEGQKLDVD 12777
+ + +YW + S + S+ A+ + +++D
Sbjct: 3888 YEPAFQGDENVRIDAMDIYVKGNKIYWTNWHTGRISYCELPASSAASTASNRNRRQIDGG 3947
Query: 12778 FAAMGV----VPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVC 12945
+ + +P IAVD+ GN++ ++ I V
Sbjct: 3948 VTHLNISGLKMPRGIAVDWVAGNIYWTDSGRDV-----------------------IEVA 3984
Query: 12946 LPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVF 13125
G K +++G + +P A++ P G + +SD G H KIE A MDGT R+ +V+D +
Sbjct: 3985 QMKGENRKTLISGMIDEPHAIVVDPLRGTMYWSDWGNHPKIETAAMDGTLRETLVQDNIQ 4044
Query: 13126 SPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDR---HIPYAVDVFENHIYW 13296
PT +A+D R+YW D K + ++ ++G++ + ++ P+++D+FE++IY
Sbjct: 4045 WPTGLAVDY-HNERLYWADAKLSVIGSIRLNGTDPVVAIDNKKGLSHPFSIDIFEDYIYG 4103
Query: 13297 LSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVS 13476
++ + ++ KFG V+ L S L V + +Y + + C+R +C LC+
Sbjct: 4104 VTYINNRIFKIHKFGHKSVTNLTSGLNHATDVVLYHQYKQ--PEVTNPCDRKKCEWLCLL 4161
Query: 13477 LPSTGFACLCPDGIVPQLD-GSC------ATQHVEALTMPKQCKCTNGGKC----RLDGS 13623
PS G C CP+G +LD G+C V T C NGG C R
Sbjct: 4162 SPS-GPVCTCPNG--KRLDNGTCVLIPSPTASAVVPTTDTCDLVCLNGGSCFLNARKQAK 4218
Query: 13624 CECTSDFEGDQCE 13662
C C + G++C+
Sbjct: 4219 CRCQPRYNGERCQ 4231
Score = 363 bits (933), Expect = 5e-98
Identities = 289/1021 (28%), Positives = 443/1021 (43%), Gaps = 26/1021 (2%)
Frame = +1
Query: 145 ASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXX-PHPGCKSDQWQCDTYTWHSV 321
++ C+ N F C G+CI W +P C + +T ++
Sbjct: 930 SARTCSPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPTC----FPLTQFTCNNG 985
Query: 322 SCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRD 501
CI RCDN DC D SDE C S CSS N F C GR C V CDG DC D
Sbjct: 986 RCININWRCDNDNDCGDNSDEAGCSHS---CSS-NQFKCNSGR-CIPVHWTCDGDNDCGD 1040
Query: 502 LSDEKDS-CSRNHT----ACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCE--F 660
SDE + C+ T C +F+C CI W CDG DC D SDE + CE
Sbjct: 1041 YSDETHANCTNQATRPPGGCHTDEFQCRLDGLCIPMRWRCDGDTDCMDSSDEKN-CEGVT 1099
Query: 661 KKCTAN-EFQCKNK-RCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPG-TGHCID 831
C N +F CK+ RC + + CD DC DNSDE+ C C P C T C+
Sbjct: 1100 HVCDPNVKFGCKDSARCISKAWVCDGDSDCEDNSDEENCESLVCKPPSHTCANNTSICLP 1159
Query: 832 QLKLCDGSKDCADGADEQQ-CSQNLCPSLGCQAGCHPSPHGG-ECTCPSGYKLDDRFHRT 1005
KLCDGS DC DG+DE + C Q + GC C +P G C+CP G +L ++T
Sbjct: 1160 PEKLCDGSDDCGDGSDEGELCDQCSLNNGGCSHNCTVAPGEGIVCSCPLGMELGAD-NKT 1218
Query: 1006 CSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKM 1185
C + CA+ C Q C + CSC + M G+ C S + K
Sbjct: 1219 CQIQSYCAKHLKCSQKCEQDKYNVKCSC----YEGWMLEPDGES-------CRSLDPFKP 1267
Query: 1186 KLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDD 1365
+ + R + R++ D V I +DF ++WTD + + + +
Sbjct: 1268 FIIFSNRHEIRRIDLHRGDYSVLVPGLRNTI-ALDFHLNQSSLYWTDVVEDKIYRGKLLE 1326
Query: 1366 EGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTL 1545
G ++ + + L P LAVDWI +Y +ES +I+V+ DG RT LLA +
Sbjct: 1327 NGALTSFEVVIQYGLATPEGLAVDWIAGNIYWVESNLDQIEVAKLDGTMRTTLLAGDIEH 1386
Query: 1546 PLDIALDPLRGEMFFT----NQLKLEAAAMDGTNRRTLVNTHTHQ---VSGIVVDITAKR 1704
P IALDP G +F+T + ++EAA+M G RRT ++ T +G+ VD KR
Sbjct: 1387 PRAIALDPRYGILFWTDWDASLPRIEAASMSGAGRRT-IHKETGSGGWPNGLTVDYLEKR 1445
Query: 1705 VYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKF 1884
+ W+D + D + S Y G V +G + HPF + L+ +YWTDW + + K+
Sbjct: 1446 ILWIDARSDAIYSALYDGTGHIEVLRGHEYLSHPFAVTLYGGEVYWTDWRTNTLAKANKW 1505
Query: 1885 GSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDN 2064
+ T N P + YHP QP + C A + PC++ +C+++
Sbjct: 1506 TGHNVTVVQRT--NTQPFDLQVYHPSRQP-LAPNPCEANGGKGPCSH-----LCLIN--- 1554
Query: 2065 GGFGVGYKCACPIGQKL-VNGKRCIDSIDYLLFSSNKIVRGIFPEINEKALAEAVLPISP 2241
+ CACP KL + C + +LL++ +RG+ +I+ + P
Sbjct: 1555 --YNRTLSCACPHLMKLDKDNTTCYEFKKFLLYARQMEIRGV--DIDNPYYNYIISFTVP 1610
Query: 2242 ISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWI 2421
I V+ D +++D+ TI R +G G V+ +S DW+
Sbjct: 1611 ----DIDNVTVVDYDAVEQRIYWSDVRTQTIKRAFINGTGVETVVSADLPNAHGLSVDWV 1666
Query: 2422 SKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKGLLFYAEAM 2601
S+ L++ N ++ + D + +I L P +VVHP G L++ +
Sbjct: 1667 SRNLFWTSYDTNKKQI------NVARLDGSFKNAVIQGLDKPHCLVVHPLHGKLYWTDGD 1720
Query: 2602 RPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKN--- 2772
I ++DG N ++ G P +AID+ E++L W + TI+ + DG +
Sbjct: 1721 N---ISVANMDGSNRTLLFTNQRG-PVGLAIDYPESKLYWISSGNGTINRCNLDGSDLEV 1776
Query: 2773 VVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKA 2952
+V + A+ IM + +++ Q + +KK+G ++R + +K
Sbjct: 1777 IVAVKSQLSKATALAIMGDKLWWADQASERMGTCNKKDGTEVTVLRN---STTLVMLMKV 1833
Query: 2953 CSHQNQPIPDDSREHPCRAS--QCTQLCFATPSESHPNELEAKCACRQGFMINKENNHSC 3126
Q + +PC + C+QLC T +E C C G+ + K SC
Sbjct: 1834 YDESIQ----QAGSNPCSVNNGDCSQLCLPT------SETSRSCMCTAGYSL-KSGQQSC 1882
Query: 3127 Q 3129
+
Sbjct: 1883 E 1883
Score = 324 bits (831), Expect = 3e-86
Identities = 222/681 (32%), Positives = 311/681 (45%), Gaps = 19/681 (2%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXX---XXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSC 327
C N F C G+CI W C Q++C+ + C
Sbjct: 2690 CPANYFACPSGRCIPMTWTCDKEDDCENGEDETHCSERQDKFCYPVQFECNNHR-----C 2744
Query: 328 IAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLS 507
I++ CD DC DGSDE D CS+ + F C C CDG DC D +
Sbjct: 2745 ISKLWVCDGADDCGDGSDE-DSRCRLTTCSTGS-FQCPGTYVCVPERWLCDGDKDCADGA 2802
Query: 508 DEK--DSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANE 681
DE C N+T C + +F C ++ QCI K +VCD DC DGSDE CE+ C +E
Sbjct: 2803 DETLAAGCLYNNT-CDEREFMCGNR-QCIPKHFVCDHDDDCGDGSDESPECEYPTCGPHE 2860
Query: 682 FQCKNKRC-QPRKFRCDYYDDCGDNSDE----DECG--EYRCPPGKWNCPGTGHCIDQLK 840
F+C N RC ++ CD DC D+SDE C E +C + C G CI +
Sbjct: 2861 FRCANGRCLSNSQWECDGEFDCHDHSDEAPKNPRCSSPESKCNDSFFMCK-NGKCIPEAL 2919
Query: 841 LCDGSKDCADGADEQQCSQNLCPS---LGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCS 1011
LCD + DCADG+DE C N C + GC C G +C C G++L D +TC
Sbjct: 2920 LCDNNNDCADGSDELNCFINECLNKKLSGCSQECEDLKIGYKCRCRPGFRLKDD-GKTCI 2978
Query: 1012 DINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKL 1191
DI+EC+ C Q C N + C C+ + + L+ DN T C + ++ L
Sbjct: 2979 DIDECSTTYPCSQKCINTLGSYKCLCI-EGYKLK------PDNPTS---CKAVTDEEPFL 3028
Query: 1192 FVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEG 1371
A R L +LN + + K + +DFDY ++ I+WTD + + G
Sbjct: 3029 IFANRYYLRKLNLDGSNYTLLKQGLNNAV-ALDFDYREQMIYWTDVTTQGSMIRRMHING 3087
Query: 1372 EISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPL 1551
S ++ L L P LAVDW+ LY + G I+VS +G RTVL+ GL P
Sbjct: 3088 --SNVQVLHRTGLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVNSGLREPR 3145
Query: 1552 DIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDP 1722
+ +D G +++T + + MDGTNR +V+T +G+ +D R+YW D
Sbjct: 3146 ALVVDVQNGYLYWTDWGDHSLIGKIGMDGTNRSVIVDTKITWPNGLTLDYINSRIYWADA 3205
Query: 1723 KVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKL 1902
+ D +E G++R V +PH F L LF+ Y+YWTDW + + K K
Sbjct: 3206 REDYIEFASLDGSNRHTVLS--QDIPHIFALTLFEDYIYWTDWETKSINRAHKTTGANKT 3263
Query: 1903 LWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVG 2082
L +T + PM I YHP QP C NA C +C+LS G G
Sbjct: 3264 LLISTLHR--PMDIHIYHPYRQPDVPNHPC-------KTNNAGCSNLCLLSP-----GGG 3309
Query: 2083 YKCACPIGQKL-VNGKRCIDS 2142
+KCACP L +GK C+ +
Sbjct: 3310 HKCACPTNFYLGSDGKTCVSN 3330
Score = 320 bits (819), Expect = 8e-85
Identities = 223/745 (29%), Positives = 330/745 (43%), Gaps = 83/745 (11%)
Frame = +1
Query: 139 NTASSVCNENDFRCND-GKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWH 315
N C ++FRC D G+CI W P + D+ C+ Y +
Sbjct: 3485 NCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDGSD-----EPKEECDERTCEPYQFR 3539
Query: 316 SVS--CIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKY 489
+ C+ +CD DC D SDE+ C T S++ F CA+GR C KCDG +
Sbjct: 3540 CKNNRCVPGRWQCDYDNDCGDNSDEESC---TPRPCSESEFSCANGR-CIAGRWKCDGDH 3595
Query: 490 DCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDT-CEFKK 666
DC D SDEKD R C Q++C + CI W CD DC DG+DE D +
Sbjct: 3596 DCADGSDEKDCIPR----CEFDQYQCKNG-HCIPMRWRCDADADCMDGTDEEDCGTGVRT 3650
Query: 667 CTANEFQCKNKRCQPRKFRCDYYDDCGDNSDE--DECGEYRCPPGK-----------W-- 801
C +EFQC N +P ++CD DDCGDNSDE +EC +++CPP + W
Sbjct: 3651 CPLDEFQCNNTLRKPLAWKCDGEDDCGDNSDENPEECLKFQCPPNRPFRCKNDRVCLWIG 3710
Query: 802 -NCPGTGHCIDQLK---------------------LCDGSK------------DCADGAD 879
C G +C D LC+ K DC DG+D
Sbjct: 3711 RQCDGIDNCGDNTDEKDCESPTAKPKSCSQDKNEFLCENKKCISANLRCNFFDDCGDGSD 3770
Query: 880 EQQCSQN-----------LCPSLGCQAGCHPSPHGGECTCPSGY-KLDDRFHRTCSDINE 1023
E+ CS +C G +A C + CTC G+ K+ D+ +C D+NE
Sbjct: 3771 EKSCSHEHKSYDCMTNTTMC---GDEAQCIQAQSSTYCTCRRGFQKVPDK--NSCQDVNE 3825
Query: 1024 CAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVAR 1203
C FG C QLC N + CSC K+ + C + ++ L++A
Sbjct: 3826 CLRFGTCSQLCNNTKGSHVCSC-------------AKNFMKTDNMCKAEGSEHQILYIAD 3872
Query: 1204 REGLYRLNPKNPDEEVKKLASGEF---IYGIDFDYGDRKIFWTD----RLAH-------S 1341
+ + P NP+ + G+ I +D KI+WT+ R+++ +
Sbjct: 3873 DNKIRSMYPFNPNSAYEPAFQGDENVRIDAMDIYVKGNKIYWTNWHTGRISYCELPASSA 3932
Query: 1342 AFSADVDDEGEISQ-IKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRT 1518
A +A + +I + L++ L PR +AVDW+ +Y +SG I+V+ GE R
Sbjct: 3933 ASTASNRNRRQIDGGVTHLNISGLKMPRGIAVDWVAGNIYWTDSGRDVIEVAQMKGENRK 3992
Query: 1519 VLLADGLTLPLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVD 1689
L++ + P I +DPLRG M+++ N K+E AAMDGT R TLV + +G+ VD
Sbjct: 3993 TLISGMIDEPHAIVVDPLRGTMYWSDWGNHPKIETAAMDGTLRETLVQDNIQWPTGLAVD 4052
Query: 1690 ITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVI 1869
+R+YW D K+ + SI G D + + HPF + +F+ Y+Y + +
Sbjct: 4053 YHNERLYWADAKLSVIGSIRLNGTDPVVAIDNKKGLSHPFSIDIFEDYIYGVTYINNRIF 4112
Query: 1870 QVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCI 2049
++ KFG K + + T + YH QP ++ NPC CE +C+
Sbjct: 4113 KIHKFGH--KSVTNLTSGLNHATDVVLYHQYKQP----------EVTNPCDRKKCEWLCL 4160
Query: 2050 LSKDNGGFGVGYKCACPIGQKLVNG 2124
LS G C CP G++L NG
Sbjct: 4161 LSPS------GPVCTCPNGKRLDNG 4179
Score = 243 bits (619), Expect = 1e-61
Identities = 231/894 (25%), Positives = 373/894 (40%), Gaps = 49/894 (5%)
Frame = +1
Query: 3802 ESCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGR--QCSSDQFKC-GNGR 3972
++C+P QF C CI W+ SDE C + +C ++ C G
Sbjct: 27 KTCSPKQFACKDQITCISKGWRCDGEKDCPDGSDESPDICPQSKVSRCQPNEHNCLGTEL 86
Query: 3973 CILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDGKT 4152
CI + LC+G +DC DGSD
Sbjct: 87 CIHMSKLCNGLHDCFDGSD----------------------------------------- 105
Query: 4153 HCPGGTDEGGRCARDLCSADRAGCSFKCHNSPNGPICSCPFGEQLV-NKTKCEPENECLD 4329
EG C L + GC C + +GP C C QL ++ C+ +EC
Sbjct: 106 -------EGPHCREQLANCTALGCQHHCVPTLSGPACYCNNSFQLAEDRRSCKDFDECTV 158
Query: 4330 SSSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTR--IYVSNRNRI---YYSD 4494
+CSQ C + + +TCSC EGY L D R+CK + D + ++N I Y S
Sbjct: 159 YGTCSQTCTNTEGSYTCSCVEGYLLQPDNRSCKAKNEPVDRPPVLLIANSQNILATYLSG 218
Query: 4495 HKLDNWHTFGAIVENAIALAWDSLTDRIYW---SDIREKKILSA----NRNG--TNATVF 4647
+ N A + A+ ++ + D + W D + IL N G ++
Sbjct: 219 APVPNITPTSA--KQTTAMDFNYIEDTVCWVHVGDSASQTILKCAKIPNLKGFVEERSIN 276
Query: 4648 IADGLDITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPR 4827
I+ L E +A+DW+ N Y+VD + I V N TLL + P+GIA+DP
Sbjct: 277 ISLSLHQVEQMAIDWLTGNFYFVDDIDDRIFVCNKNGLTCVTLL-DLELYNPKGIALDPA 335
Query: 4828 KGVMFWTDWGQNPCIERASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDF 5007
G +F+TD+GQ P +ER MDG +R +V +KI +P+ I LD + VY+AD+ LD+I+
Sbjct: 336 MGKVFFTDYGQIPKVERCDMDGQNRTKLVDSKIVFPHGITLDLVSRLVYWADAYLDYIEV 395
Query: 5008 VNYDGSGRTQVLASSKFVQHPHALAIFEDMMYYSD----RRLQKLQVYPKYPNGTTSEYP 5175
V+Y+G R ++ ++H + L +FE+ +Y ++ QK V + ++EY
Sbjct: 396 VDYEGKNRHTII-QGILIEHLYGLTVFENYLYATNSDNANAQQKTSVI-RVNRFNSTEYQ 453
Query: 5176 SHTFSKALGVVAV-HPVLQPVIKNNPCSTNP------CSHLCLLNNKN-TFTCKCPMGEK 5331
T G + + H QP ++++ C + CS +CLL N + + TC+C G
Sbjct: 454 VVTRVDKGGALHIYHQRRQPTVRSHACEPDQFGKPGGCSDICLLGNSHKSRTCRCRSGFS 513
Query: 5332 LDASGKKCIDDAKPFLVIIQKTN---VFGIEMNSASEKETPVLAGMVPLSGLGNAFDAAY 5502
L + GK C ++ K + G++M + E M+P+ L N A
Sbjct: 514 LGSDGKSCKKPEHELFLVYGKGRPGIIRGMDMGAKVPDE-----HMIPIENLMN--PRAL 566
Query: 5503 DALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGR 5682
D +E FI TT I R ++G + + + + + DW G
Sbjct: 567 DFHAETGFI---------YFADTTSYLIGRQKIDGTERETILKDGI-HNVEGIAVDWMGN 616
Query: 5683 NLV-VGNKITQTIEIIRTQ-GKQYRSVILSNDQSXXXXXXXXXXXXXXXKGYVFWLDRGG 5856
NL + +TI + R + Q R ++ + G+++W D
Sbjct: 617 NLYWTDDGPKKTISVARLEKAAQTRKTLIEGKMT-----HPRAIVVDPLNGWMYWTDWEE 671
Query: 5857 GAADA---KVARAGLDGSNPLV-IASNDLAELDHIAIDTTNTRVYFSEAKAGRISSVTYD 6024
D+ K+ RA +DGSN V I S + + +++D +Y+ +A RI V +
Sbjct: 672 DPKDSKRGKIERAWMDGSNRNVFITSKTVLWPNGLSLDIPAKILYWVDAFYDRIEMVYLN 731
Query: 6025 GQDRHYVLSDGGRQPN---GLAFYGDRLFYADSAFDSI-------EVATINGDSQPPQWT 6174
G +R V G + N GL Y LF+ + SI + ++ + +PP
Sbjct: 732 GTERKIVYE--GPELNHAFGLCHYSSFLFWTEYRSGSIYRLDQSSKAVSLLRNERPP--- 786
Query: 6175 HFKKDVENLANIKALQPRASSSGHPCHINNGNCDHICIPLMFAQRTCTCANGYV 6336
+ + A Q + S + C +NNG C +C+ R C CA +
Sbjct: 787 -----IFEIRMYDAQQQQVGS--NKCRVNNGGCSSLCLATP-RGRQCACAEDQI 832
Score = 180 bits (456), Expect = 1e-42
Identities = 92/246 (37%), Positives = 124/246 (50%), Gaps = 1/246 (0%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAE 336
C F+C+ G C + C Q++C ++ CI
Sbjct: 3371 CRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCT----NTNRCIPG 3426
Query: 337 YQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEK 516
RC+ +C DG DEKDCP T + N F CA ++C CD DC D SDE
Sbjct: 3427 IFRCNGQDNCGDGEDEKDCPEVTC---APNQFQCAITKRCIPRVWVCDRDNDCVDGSDEP 3483
Query: 517 DSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEP-DTCEFKKCTANEFQCK 693
+C++ C +FRC D +CI W CDG DC DGSDEP + C+ + C +F+CK
Sbjct: 3484 ANCTQ--MTCGVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCK 3541
Query: 694 NKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADG 873
N RC P +++CDY +DCGDNSDE+ C C +++C G CI CDG DCADG
Sbjct: 3542 NNRCVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFSC-ANGRCIAGRWKCDGDHDCADG 3600
Query: 874 ADEQQC 891
+DE+ C
Sbjct: 3601 SDEKDC 3606
Score = 171 bits (433), Expect = 5e-40
Identities = 147/605 (24%), Positives = 234/605 (38%), Gaps = 27/605 (4%)
Frame = +1
Query: 9139 RTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEK-KECNKGEF 9315
+TC+ ++F C + + CI + W CDG+ C G DES ++C K C E
Sbjct: 27 KTCSPKQFAC-------KDQITCISKGWRCDGEKDCPDGSDESPDICPQSKVSRCQPNEH 79
Query: 9316 RC-SNQHCIHSTWECDGDNDCLDGSDEH-------ANCTYSSCQPDFFQCANHKCVPNSW 9471
C + CIH + C+G +DC DGSDE ANCT CQ H CVP
Sbjct: 80 NCLGTELCIHMSKLCNGLHDCFDGSDEGPHCREQLANCTALGCQ--------HHCVPT-- 129
Query: 9472 KCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSD 9651
SG A C+ +F + D
Sbjct: 130 -------------------------------------LSG----PACYCNNSFQLAE--D 146
Query: 9652 ESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNECYEGISGC 9831
S DEC++ C Q C + + Y C C EG+ + D +SC NE
Sbjct: 147 RRSCKDFDECTV--YGTCSQTCTNTEGSYTCSCVEGYLLQ-PDNRSCKAKNE-------- 195
Query: 9832 SQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKY-EL 10008
++ P L+AN I + G +
Sbjct: 196 -------------------------------PVDRPPVLLIANSQNILATYLSGAPVPNI 224
Query: 10009 AAQGFDNVVSLDIDLTEKK---AYLIDQGKLRLLR-VDLDEMDSPLSSYETVLRHNVYGT 10176
++D + E ++ D +L+ + + + + +++
Sbjct: 225 TPTSAKQTTAMDFNYIEDTVCWVHVGDSASQTILKCAKIPNLKGFVEERSINISLSLHQV 284
Query: 10177 EGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFFTEW 10356
E +A+DW+ Y ++ + I VC +G C TL+ + PK I + P G +FFT++
Sbjct: 285 EQMAIDWLTGNFYFVDDIDDRIFVCNKNGLTCVTLLDLELYNPKGIALDPAMGKVFFTDY 344
Query: 10357 SLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFD 10536
P + R +DG KL + + +P+ I +D S ++W DA+L+ I +D++
Sbjct: 345 GQIPKVERCDMDGQNRT-----KLVDSKIVFPHGITLDLVSRLVYWADAYLDYIEVVDYE 399
Query: 10537 GNGRRH-IPAQRTSHVSSMVVFDDYLYWAD------WNLREVLRCDKWTGKNETILKKTV 10695
G R I H+ + VF++YLY + V+R +++ ++ + V
Sbjct: 400 GKNRHTIIQGILIEHLYGLTVFENYLYATNSDNANAQQKTSVIRVNRFNSTEYQVVTR-V 458
Query: 10696 QLPNDLRIVHPMRQPAY------PNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSD 10857
L I H RQP P+ G GGCS +CL+G TC C F L SD
Sbjct: 459 DKGGALHIYHQRRQPTVRSHACEPDQFG-KPGGCSDICLLGNSHKSRTCRCRSGFSLGSD 517
Query: 10858 QKTCE 10872
K+C+
Sbjct: 518 GKSCK 522
Score = 140 bits (352), Expect = 1e-30
Identities = 107/349 (30%), Positives = 149/349 (42%), Gaps = 31/349 (8%)
Frame = +1
Query: 148 SSVCNEND-FRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQ-------CDT 303
+S CN +D F C +G CI H KSD+ Q C
Sbjct: 2515 NSTCNVHDEFECGNGDCI------------DFSRTCDGVVHCKDKSDEKQSYCSSRKCKK 2562
Query: 304 YTWHSVS--CIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKC 477
H ++ C+A C+ + DC D SDE C + C++ F C DG C S +C
Sbjct: 2563 GFLHCMNGRCVASRFWCNGVDDCGDNSDEVPC--NKTSCAATE-FRCRDG-SCIGNSSRC 2618
Query: 478 DGKYDCRDLSDEKDSCSRNHTACFQYQFR------CADKTQCIQKSWVCDGSKDCADGSD 639
+ DC D SDE + + + ++ F+ + C + C SWVCDG+ DC D SD
Sbjct: 2619 NQFIDCEDASDEMNCTATDCSSYFKLGVKGTTFQKCEHTSLCYAPSWVCDGANDCGDYSD 2678
Query: 640 EPDTCEFKK--CTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYR---CPPGKWN 804
E + +K C AN F C + RC P + CD DDC + DE C E + C P ++
Sbjct: 2679 ERNCPGGRKPKCPANYFACPSGRCIPMTWTCDKEDDCENGEDETHCSERQDKFCYPVQFE 2738
Query: 805 CPGTGHCIDQLKLCDGSKDCADGADE-QQCSQNLCPSLGCQAG----CHPSPH--GGECT 963
C CI +L +CDG+ DC DG+DE +C C + Q C P G+
Sbjct: 2739 C-NNHRCISKLWVCDGADDCGDGSDEDSRCRLTTCSTGSFQCPGTYVCVPERWLCDGDKD 2797
Query: 964 CPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHR---PGFTCSCLGDC 1101
C G D+ C N C E + +C N + F C DC
Sbjct: 2798 CADG--ADETLAAGCLYNNTCDEREF---MCGNRQCIPKHFVCDHDDDC 2841
Score = 130 bits (328), Expect = 7e-28
Identities = 90/264 (34%), Positives = 127/264 (48%), Gaps = 11/264 (4%)
Frame = +1
Query: 343 RCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDS 522
+C T+ GSD K C ++ C++ F+C + + C KCD + DC D SDE +
Sbjct: 3311 KCACPTNFYLGSDGKTCVSN---CTASQ-FVCKNDK-CIPFWWKCDTEDDCGDRSDEPED 3365
Query: 523 CSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKN-K 699
C C QF+C+ C +++CDG DC D SDE + C+ C ++F+C N
Sbjct: 3366 CPE--FKCRPGQFQCSTGI-CTNPAFICDGDNDCQDNSDEAN-CDIHVCLPSQFKCTNTN 3421
Query: 700 RCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGAD 879
RC P FRC+ D+CGD DE +C E C P ++ C T CI ++ +CD DC DG+D
Sbjct: 3422 RCIPGIFRCNGQDNCGDGEDEKDCPEVTCAPNQFQCAITKRCIPRVWVCDRDNDCVDGSD 3481
Query: 880 E-QQCSQNLC--PSLGCQ--AGCHPS--PHGGECTCPSGYKLDDRFHRTCSDINECAEFG 1038
E C+Q C C+ C P+ GE C G D C D C +
Sbjct: 3482 EPANCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDG---SDEPKEEC-DERTCEPYQ 3537
Query: 1039 YCDQLCANHR--PG-FTCSCLGDC 1101
+ C N+R PG + C DC
Sbjct: 3538 F---RCKNNRCVPGRWQCDYDNDC 3558
Score = 129 bits (324), Expect = 2e-27
Identities = 82/242 (33%), Positives = 104/242 (42%), Gaps = 14/242 (5%)
Frame = +1
Query: 430 FMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCD 609
F C + R C KCDG DC D SDE HT C +F+C + +CI W+CD
Sbjct: 857 FACKNNR-CIQERWKCDGDNDCLDNSDEAPELCHQHT-CPSDRFKCKN-NRCIPNRWLCD 913
Query: 610 GSKDCADGSDEPD-TCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDED-ECGEYR 783
G DC + DE + TC + C+ N+F C + RC P + CD DDCGD SDE C
Sbjct: 914 GDNDCGNNEDESNSTCSARTCSPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPT 973
Query: 784 CPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECT 963
C P G CI+ CD DC D +DE AGC S +
Sbjct: 974 CFPLTQFTCNNGRCININWRCDNDNDCGDNSDE--------------AGCSHSCSSNQFK 1019
Query: 964 CPSGYKLDDRFHRTCSDINECAEFGYCDQLCAN------------HRPGFTCSCLGDCFT 1107
C SG + H TC N+C + Y D+ AN H F C G C
Sbjct: 1020 CNSGRCIP--VHWTCDGDNDCGD--YSDETHANCTNQATRPPGGCHTDEFQCRLDGLCIP 1075
Query: 1108 LQ 1113
++
Sbjct: 1076 MR 1077
Score = 125 bits (315), Expect = 2e-26
Identities = 138/626 (22%), Positives = 238/626 (37%), Gaps = 26/626 (4%)
Frame = +1
Query: 11743 RRCLPGHRQCDDG-TCIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFECANSVCIP 11919
+ C P C D TCI++ CD +KDCP+ +DE
Sbjct: 27 KTCSPKQFACKDQITCISKGWRCDGEKDCPDGSDE------------------------- 61
Query: 11920 RKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFS 12099
S + + + ++C P C + LC+++ +LCNG +DC
Sbjct: 62 --------------SPDICPQSKVSRCQPN-EHNCLGTELCIHMSKLCNGLHDC------ 100
Query: 12100 DEHLSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCE 12279
D SDE G +C
Sbjct: 101 -----------------------------------------FDGSDE-GPHCREQLANCT 118
Query: 12280 AFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGSY 12459
A GC+H C G C+C + F+ + + C D DEC TC+Q C NT+GSY
Sbjct: 119 AL----GCQHHCVPTLSGPACYCNNSFQL-AEDRRSCKDFDECTVYGTCSQTCTNTEGSY 173
Query: 12460 LCRCHEDYENNVVVGSMTGKDCRAKGDAAN----VMIGADDSLVQLSLHGSGTNRHXXXX 12627
C C E Y + + C+AK + + ++I +++ L G+
Sbjct: 174 TCSCVEGY-----LLQPDNRSCKAKNEPVDRPPVLLIANSQNILATYLSGAPVPNITPTS 228
Query: 12628 XXXXXXXXXXXXXXPRKELMYWI---DGSERTIYRSA-IANGNQSHEGQKLDVDFAAMGV 12795
++ + W+ D + +TI + A I N E + +++ + V
Sbjct: 229 AKQTTAMDFNYI----EDTVCWVHVGDSASQTILKCAKIPNLKGFVEERSINISLSLHQV 284
Query: 12796 VPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKI 12975
+A+D+ TGN + + ID++ IFVC +G +
Sbjct: 285 --EQMAIDWLTGNFYFV-------------------DDIDDR----IFVCNKNGLTCVTL 319
Query: 12976 VAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEG 13155
+ L P + P+ G++ ++D G K+E DMDG +R +V + P + +D
Sbjct: 320 LDLELYNPKGIALDPAMGKVFFTDYGQIPKVERCDMDGQNRTKLVDSKIVFPHGITLDL- 378
Query: 13156 KGNRIYWVDPKYRRVDAVNIDGSERTTVVHD---RHIPYAVDVFENHIYWLSRES----- 13311
+YW D ++ V+ +G R T++ H+ Y + VFEN++Y + ++
Sbjct: 379 VSRLVYWADAYLDYIEVVDYEGKNRHTIIQGILIEHL-YGLTVFENYLYATNSDNANAQQ 437
Query: 13312 KTLYVQ-DKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQ------CSHLC 13470
KT ++ ++F V+ + ++ G + + + + T R+ CE Q CS +C
Sbjct: 438 KTSVIRVNRFNSTEYQVV-TRVDKGGALHIYHQRRQPTVRS-HACEPDQFGKPGGCSDIC 495
Query: 13471 VSLPS-TGFACLCPDGIVPQLDG-SC 13542
+ S C C G DG SC
Sbjct: 496 LLGNSHKSRTCRCRSGFSLGSDGKSC 521
Score = 109 bits (272), Expect = 2e-21
Identities = 59/172 (34%), Positives = 79/172 (45%)
Frame = +1
Query: 391 CPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCA 570
C + CS+ + G +C C + L + +C N TA QF C
Sbjct: 3291 CKTNNAGCSNLCLLSPGGGHKC-----ACPTNFY---LGSDGKTCVSNCTAS---QFVCK 3339
Query: 571 DKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGD 750
+ +CI W CD DC D SDEP+ C KC +FQC C F CD +DC D
Sbjct: 3340 ND-KCIPFWWKCDTEDDCGDRSDEPEDCPEFKCRPGQFQCSTGICTNPAFICDGDNDCQD 3398
Query: 751 NSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLC 906
NSDE C + C P ++ C T CI + C+G +C DG DE+ C + C
Sbjct: 3399 NSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDEKDCPEVTC 3450
Score = 107 bits (266), Expect = 1e-20
Identities = 139/629 (22%), Positives = 230/629 (36%), Gaps = 33/629 (5%)
Frame = +1
Query: 7180 PRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCARGVLKGRT---CEEPDTYIMF-SD 7347
P +S + + LR C+QLC T G+ CSCA+ +K E + I++ +D
Sbjct: 3815 PDKNSCQDVNECLRFGTCSQLCNNTKGSHV--CSCAKNFMKTDNMCKAEGSEHQILYIAD 3872
Query: 7348 GDKIIDV-------AIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFV--------- 7479
+KI + A EP + ++ + D+ V ++Y+
Sbjct: 3873 DNKIRSMYPFNPNSAYEPAFQGDENVR--------IDAMDIYVKGNKIYWTNWHTGRISY 3924
Query: 7480 VESPVGVNISWFSMNNAENPRLVFGASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKV 7659
E P S S + N R + G + ++ + +DW+ IY+T +
Sbjct: 3925 CELPAS---SAASTASNRNRRQIDGGVTHLNISGLKMPRGIAVDWVAGNIYWTDSGRDVI 3981
Query: 7660 MAIDTAGEHLSTIASG--DWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGS 7833
GE+ T+ SG D +A+ +DP G ++WSD G P+IE + + G
Sbjct: 3982 EVAQMKGENRKTLISGMIDEPHAIVVDPLRGTMYWSDWG-------NHPKIETAAMDGTL 4034
Query: 7834 RKVIVSESISLPAAIAVDFRNQKIYWADVN-------RLNIEVADYDGQNRKVIASGYRA 7992
R+ +V ++I P +AVD+ N+++YWAD RLN N+K ++ +
Sbjct: 4035 RETLVQDNIQWPTGLAVDYHNERLYWADAKLSVIGSIRLNGTDPVVAIDNKKGLSHPF-- 4092
Query: 7993 KSLDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVC 8172
S+DI++ ++Y ++N +F+I K + N+ S +DV +Q
Sbjct: 4093 -SIDIFEDYIYGVTYINNRIFKIHKFGHKSVTNLTSG---------LNHATDVVLYHQYK 4142
Query: 8173 NALTSQLCKTDNGGCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGS 8352
+ C D C+ LC L+ S C+C + L D T ++
Sbjct: 4143 QPEVTNPC--DRKKCEWLCL-------LSPSGPVCTCPNGKRL------DNGTCVLIPSP 4187
Query: 8353 NSEPAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNR 8532
+ + C +G L A +K C P Y R C
Sbjct: 4188 TASAVVPTTDTCDLVCLNGGSCFLNARKQAKCRC------QPRYNGER--------CQIN 4233
Query: 8533 RCIDSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQV 8712
+C D + G CP+ + C C T C + C Q
Sbjct: 4234 QCSDYCQNGGLCTASPSGMPTCRCPTGFTGSR----CDQQVC---TNYCHNNGSCTVNQ- 4285
Query: 8713 SDESLATCPGLPIDCRGVKVR----CPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQ 8880
++ CP I R + C N +C DG C C + +
Sbjct: 4286 GNQPNCRCPPTFIGDRCQYQQCFNYCENNGVCQMSR---DGVKQCRCPPQFEGAQCQDNK 4342
Query: 8881 CAQHYVRCPSGRCIPETWQCDGDNDCSDG 8967
C+ RC G+C D C DG
Sbjct: 4343 CS----RCQEGKCNINRQSGDVSCICPDG 4367
Score = 94.0 bits (232), Expect = 1e-16
Identities = 62/196 (31%), Positives = 83/196 (41%), Gaps = 5/196 (2%)
Frame = +1
Query: 463 VSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDE 642
V+ C G+ R L ++ + N T +F C + CI S CDG C D SDE
Sbjct: 2495 VNCSCRGE---RVLQEDFTCKALNSTCNVHDEFECGNG-DCIDFSRTCDGVVHCKDKSDE 2550
Query: 643 PDT-CEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTG 819
+ C +KC C N RC +F C+ DDCGDNSDE C + C ++ C G
Sbjct: 2551 KQSYCSSRKCKKGFLHCMNGRCVASRFWCNGVDDCGDNSDEVPCNKTSCAATEFRC-RDG 2609
Query: 820 HCIDQLKLCDGSKDCADGADEQQCSQNLCPS---LGCQAGC-HPSPHGGECTCPSGYKLD 987
CI C+ DC D +DE C+ C S LG + H C PS
Sbjct: 2610 SCIGNSSRCNQFIDCEDASDEMNCTATDCSSYFKLGVKGTTFQKCEHTSLCYAPSW---- 2665
Query: 988 DRFHRTCSDINECAEF 1035
C N+C ++
Sbjct: 2666 -----VCDGANDCGDY 2676
Score = 75.1 bits (183), Expect = 5e-11
Identities = 63/240 (26%), Positives = 93/240 (38%), Gaps = 40/240 (16%)
Frame = +1
Query: 487 YDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFK- 663
YD + + C N+ C QC C ++D G+D TCE
Sbjct: 793 YDAQQQQVGSNKCRVNNGGCSSLCLATPRGRQC-----AC--AEDQILGADSV-TCEANP 844
Query: 664 ------KCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDE--DECGEYRCPPGKWNCPGTG 819
+C EF CKN RC +++CD +DC DNSDE + C ++ CP ++ C
Sbjct: 845 SYIPPPQCQPGEFACKNNRCIQERWKCDGDNDCLDNSDEAPELCHQHTCPSDRFKCK-NN 903
Query: 820 HCIDQLKLCDGSKDCADGADEQQ--CSQNLCP--SLGCQAG-CHP--------------S 942
CI LCDG DC + DE CS C C +G C P S
Sbjct: 904 RCIPNRWLCDGDNDCGNNEDESNSTCSARTCSPNQFSCASGRCIPISWTCDLDDDCGDRS 963
Query: 943 PHGGECTCPSGYKLDD---------RFHRTCSDINEC---AEFGYCDQLCANHRPGFTCS 1086
C P+ + L + C + N+C ++ C C++++ F C+
Sbjct: 964 DESASCAYPTCFPLTQFTCNNGRCININWRCDNDNDCGDNSDEAGCSHSCSSNQ--FKCN 1021
Score = 73.9 bits (180), Expect = 1e-10
Identities = 75/305 (24%), Positives = 129/305 (41%), Gaps = 11/305 (3%)
Frame = +1
Query: 2404 MSFDWISKQLYYVDNIRNSLEVVKI-GETGLVHPDELVRRQLITELRD-PVSVVVHPWKG 2577
++ DW++ +Y+ D+ R+ +EV ++ GE R+ LI+ + D P ++VV P +G
Sbjct: 3962 IAVDWVAGNIYWTDSGRDVIEVAQMKGEN---------RKTLISGMIDEPHAIVVDPLRG 4012
Query: 2578 LLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMD 2757
+++++ I +DG + + + P+ +A+D+ RL W D L I +
Sbjct: 4013 TMYWSDWGNHPKIETAAMDGTLRETLVQDNIQWPTGLAVDYHNERLYWADAKLSVIGSIR 4072
Query: 2758 FDGKNVVKLDIDN----PIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGAD 2925
+G + V + IDN P +I I +YIY V Y R+ K + G K V +
Sbjct: 4073 LNGTDPV-VAIDNKKGLSHPFSIDIFEDYIYGV---TYINNRIFKIHKFGHKSVTNLTSG 4128
Query: 2926 ERSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMIN 3105
+ QP +PC +C LC +PS C C G
Sbjct: 4129 LNHATDVVLYHQYKQP----EVTNPCDRKKCEWLCLLSPS-------GPVCTCPNG---K 4174
Query: 3106 KENNHSCQKDPAEKIEQLCSSNST-QFQCKN-GRCI---PKEWKCDGENDCLDESDEIDE 3270
+ +N +C P+ + + T C N G C K+ KC + E +I++
Sbjct: 4175 RLDNGTCVLIPSPTASAVVPTTDTCDLVCLNGGSCFLNARKQAKCRCQPRYNGERCQINQ 4234
Query: 3271 KGDKC 3285
D C
Sbjct: 4235 CSDYC 4239
Score = 70.9 bits (172), Expect = 9e-10
Identities = 62/258 (24%), Positives = 109/258 (42%), Gaps = 20/258 (7%)
Frame = +1
Query: 12967 KKIVAGHLQQPTALITAPSAGRICYSD------AGLHAKIECADMDGTHRQI-IVKDLVF 13125
K ++ G + P A++ P G + ++D KIE A MDG++R + I V
Sbjct: 642 KTLIEGKMTHPRAIVVDPLNGWMYWTDWEEDPKDSKRGKIERAWMDGSNRNVFITSKTVL 701
Query: 13126 SPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDV--FENHIYWL 13299
P +++D +YWVD Y R++ V ++G+ER V + +A + + + ++W
Sbjct: 702 WPNGLSLDI-PAKILYWVDAFYDRIEMVYLNGTERKIVYEGPELNHAFGLCHYSSFLFWT 760
Query: 13300 SRESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSL 13479
S ++Y D+ + VS+L ++ +R+ + CS LC++
Sbjct: 761 EYRSGSIYRLDQSSKA-VSLLRNERPPIFEIRMYDAQQQQVGSNKCRVNNGGCSSLCLAT 819
Query: 13480 PSTGFACLCPDGIVPQLDGSCATQHVEALTMPKQCK-----CTNG------GKCRLDGSC 13626
P G C C + + D S + + P QC+ C N KC D C
Sbjct: 820 P-RGRQCACAEDQILGAD-SVTCEANPSYIPPPQCQPGEFACKNNRCIQERWKCDGDNDC 877
Query: 13627 ECTSDFEGDQCEKESSVS 13680
SD + C + + S
Sbjct: 878 LDNSDEAPELCHQHTCPS 895
Score = 69.7 bits (169), Expect = 2e-09
Identities = 44/130 (33%), Positives = 60/130 (45%), Gaps = 15/130 (11%)
Frame = +1
Query: 8359 EPAKECLPPYNFQCGDG-SCILLGATCDSKPDCADASDENPNYCN----TRSCPEDYNLC 8523
E K C P F C D +CI G CD + DC D SDE+P+ C +R P ++N
Sbjct: 24 EAPKTCSPK-QFACKDQITCISKGWRCDGEKDCPDGSDESPDICPQSKVSRCQPNEHNCL 82
Query: 8524 TNRRCIDSAKKCNHIDDCGDGSDE-------LDCPSAVACAEGTFPCSNG---HCINQTK 8673
CI +K CN + DC DGSDE L +A+ C P +G +C N +
Sbjct: 83 GTELCIHMSKLCNGLHDCFDGSDEGPHCREQLANCTALGCQHHCVPTLSGPACYCNNSFQ 142
Query: 8674 VCDGHNDCHD 8703
+ + C D
Sbjct: 143 LAEDRRSCKD 152
Score = 64.7 bits (156), Expect = 6e-08
Identities = 108/493 (21%), Positives = 168/493 (33%), Gaps = 27/493 (5%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDEKD--CPASTVDCSSQNVFMCADG 447
C Q+ C ++CI++ RCD DC DGSDE CP S V N C
Sbjct: 29 CSPKQFACKD----QITCISKGWRCDGEKDCPDGSDESPDICPQSKVSRCQPNEHNCLGT 84
Query: 448 RQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTAC--FQYQFRCADKTQCIQKSWVCDGSKD 621
C +SK C+G +DC D SDE C C Q C + C+ S
Sbjct: 85 ELCIHMSKLCNGLHDCFDGSDEGPHCREQLANCTALGCQHHCVPTLS--GPACYCNNSFQ 142
Query: 622 CADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRC----- 786
A+ D +F +CT Y C E G Y C
Sbjct: 143 LAE--DRRSCKDFDECTV-------------------YGTCSQTCTNTE-GSYTCSCVEG 180
Query: 787 ---PPGKWNCPGTGHCIDQ--LKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHG 951
P +C +D+ + L S++ N+ P+ Q +
Sbjct: 181 YLLQPDNRSCKAKNEPVDRPPVLLIANSQNILATYLSGAPVPNITPTSAKQTTAMDFNYI 240
Query: 952 GECTCPSGYKLDDRFHRTCSDINECAEF----GYCDQLCANHRPGFTCSCLGDCFTLQME 1119
+ C + D +T I +CA+ G+ ++ N +L
Sbjct: 241 EDTVC--WVHVGDSASQT---ILKCAKIPNLKGFVEERSIN-----------ISLSLHQV 284
Query: 1120 HGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRL--------NPKNPDEEVKKLASGEF 1275
D LT Y V + D ++FV + GL + NPK
Sbjct: 285 EQMAIDWLTGNFYFVDDIDD--RIFVCNKNGLTCVTLLDLELYNPK-------------- 328
Query: 1276 IYGIDFDYGDRKIFWTD-RLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNT 1452
GI D K+F+TD D+D + KL +V+P + +D ++
Sbjct: 329 --GIALDPAMGKVFFTDYGQIPKVERCDMDGQNR----TKLVDSKIVFPHGITLDLVSRL 382
Query: 1453 LYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTNQLKLEAAAMDGT 1632
+Y ++ I+V Y+G+ R ++ G+ + L ++ TN A
Sbjct: 383 VYWADAYLDYIEVVDYEGKNRHTII-QGILIEHLYGLTVFENYLYATNSDNANAQQKTSV 441
Query: 1633 NRRTLVNTHTHQV 1671
R N+ +QV
Sbjct: 442 IRVNRFNSTEYQV 454
Score = 54.7 bits (130), Expect = 7e-05
Identities = 33/67 (49%), Positives = 34/67 (50%)
Frame = +1
Query: 10849 LSDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEF 11028
L KTC P +QFAC D CI K W CDGE DC DGSDE IC Q V
Sbjct: 23 LEAPKTCSP----KQFACK-DQITCISKGWRCDGEKDCPDGSDE-SPDICPQ--SKVSRC 74
Query: 11029 QCTNHNC 11049
Q HNC
Sbjct: 75 QPNEHNC 81
Score = 49.7 bits (117), Expect = 0.002
Identities = 35/107 (32%), Positives = 46/107 (42%), Gaps = 9/107 (8%)
Frame = +1
Query: 11626 RPCSESEFRCNDG-KCIPGSKVCDGTIQCSDGLDES-----QCTLRRCLPGHRQC-DDGT 11784
+ CS +F C D CI CDG C DG DES Q + RC P C
Sbjct: 27 KTCSPKQFACKDQITCISKGWRCDGEKDCPDGSDESPDICPQSKVSRCQPNEHNCLGTEL 86
Query: 11785 CIAEHKWCDRKKDCPNAADE-LHC-EDVSRRTCSPFEFECANSVCIP 11919
CI K C+ DC + +DE HC E ++ T + C ++ P
Sbjct: 87 CIHMSKLCNGLHDCFDGSDEGPHCREQLANCTALGCQHHCVPTLSGP 133
Score = 48.5 bits (114), Expect = 0.005
Identities = 22/61 (36%), Positives = 31/61 (50%), Gaps = 4/61 (6%)
Frame = +1
Query: 3556 TCAANQFSCANG-RCIPIYWLCDGDNDCYDGTDEDKERCPP---VQCSALQFRCANGRQC 3723
TC+ QF+C + CI W CDG+ DC DG+DE + CP +C + C C
Sbjct: 28 TCSPKQFACKDQITCISKGWRCDGEKDCPDGSDESPDICPQSKVSRCQPNEHNCLGTELC 87
Query: 3724 V 3726
+
Sbjct: 88 I 88
Score = 47.0 bits (110), Expect = 0.014
Identities = 28/72 (38%), Positives = 35/72 (47%), Gaps = 3/72 (4%)
Frame = +1
Query: 3139 AEKIEQLCSSNSTQFQCKNG-RCIPKEWKCDGENDCLDESDEIDEKGDKCFHE--TECAE 3309
A +E + + QF CK+ CI K W+CDGE DC D S DE D C + C
Sbjct: 20 ARALEAPKTCSPKQFACKDQITCISKGWRCDGEKDCPDGS---DESPDICPQSKVSRCQP 76
Query: 3310 NTIKCRNTKKCI 3345
N C T+ CI
Sbjct: 77 NEHNCLGTELCI 88
Score = 46.6 bits (109), Expect = 0.018
Identities = 49/201 (24%), Positives = 80/201 (39%), Gaps = 9/201 (4%)
Frame = +1
Query: 11239 MSAERNCTAEEFRCNNN-KCIAKAWRXXXXXXXXXXXXETPE-CAQIE---CKKGWTRCS 11403
+ A + C+ ++F C + CI+K WR E+P+ C Q + C+ C
Sbjct: 23 LEAPKTCSPKQFACKDQITCISKGWRCDGEKDCPDGSDESPDICPQSKVSRCQPNEHNCL 82
Query: 11404 SSYRCIPNWAFCNGQDDCRDNSDED---KQRCPTCDDVGEFRCATSGKCIPRRWMCDTEN 11574
+ CI CNG DC D SDE +++ C +G C+P +
Sbjct: 83 GTELCIHMSKLCNGLHDCFDGSDEGPHCREQLANCTALG-----CQHHCVPT--LSGPAC 135
Query: 11575 DCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTLRRCL 11754
C +NS +L R C + + G C +G+ CS C+
Sbjct: 136 YC-NNSFQL----AEDRRSCKDFDECTVYGTCSQTCTNTEGSYTCS------------CV 178
Query: 11755 PGH-RQCDDGTCIAEHKWCDR 11814
G+ Q D+ +C A+++ DR
Sbjct: 179 EGYLLQPDNRSCKAKNEPVDR 199
Score = 43.9 bits (102), Expect = 0.12
Identities = 31/102 (30%), Positives = 42/102 (40%), Gaps = 10/102 (9%)
Frame = +1
Query: 8746 PIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMN---QQCAQHYVRC-PSG 8913
P C + C + CI CDG DC D +DE+ C +C + C +
Sbjct: 26 PKTCSPKQFACKDQITCISKGWRCDGEKDCPDGSDESPDICPQSKVSRCQPNEHNCLGTE 85
Query: 8914 RCIPETWQCDGDNDCSDGWD------ETHTNCTDTAGKKICV 9021
CI + C+G +DC DG D E NCT + CV
Sbjct: 86 LCIHMSKLCNGLHDCFDGSDEGPHCREQLANCTALGCQHHCV 127
>gi|4758686|ref|NP_002323.1| low density lipoprotein-related protein 1;
alpha-2-macroglobulin receptor [Homo sapiens]
gi|1708865|sp|Q07954|LRP1_HUMAN Low-density lipoprotein
receptor-related protein 1 precursor (LRP)
(Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E
receptor) (APOER) (CD91)
gi|88083|pir||S02392 alpha-2-macroglobulin receptor precursor - human
gi|34339|emb|CAA32112.1| LDL-receptor related precursor (AA -19 to
4525) [Homo sapiens]
gi|3493576|gb|AAC64265.1| lipoprotein receptor-related protein [Homo
sapiens]
Length = 4544
Score = 2030 bits (5260), Expect = 0.0
Identities = 1404/4518 (31%), Positives = 2104/4518 (46%), Gaps = 145/4518 (3%)
Frame = +1
Query: 544 CFQYQFRCADKTQCIQKSWVCDGSKDCADGSDE-PDTCEFKKCTANEFQCKNKRCQPRKF 720
C QF C D+ CI K W CDG +DC DGSDE P+ C Q K +RCQP +
Sbjct: 27 CSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICP---------QSKAQRCQPNEH 77
Query: 721 RCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADE-QQCS- 894
C G C P C G +DC DG+DE C
Sbjct: 78 NC--------------LGTELCVPMSRLCNGV-------------QDCMDGSDEGPHCRE 110
Query: 895 -QNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRP 1071
Q C LGCQ C P+ G C C S ++L +TC D +EC+ +G C QLC N
Sbjct: 111 LQGNCSRLGCQHHCVPTLDGPTCYCNSSFQL-QADGKTCKDFDECSVYGTCSQLCTNTDG 169
Query: 1072 GFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMK---LFVARREGLYRLNPKNPD 1242
F C C+ + + LQ DN + C + N + L +A + +
Sbjct: 170 SFICGCV-EGYLLQ------PDNRS----CKAKNEPVDRPPVLLIANSQNILATYLSGAQ 218
Query: 1243 EEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVD-----------DEGEISQIK 1389
S +DF Y + + W + SA + DE I+
Sbjct: 219 VSTITPTSTRQTTAMDFSYANETVCWV-HVGDSAAQTQLKCARMPGLKGFVDEHTIN--- 274
Query: 1390 KLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDP 1569
+SL SL + +A+DW+T Y ++ RI V + +G+ LL L P IALDP
Sbjct: 275 -ISL-SLHHVEQMAIDWLTGNFYFVDDIDDRIFVCNRNGDTCVTLLDLELYNPKGIALDP 332
Query: 1570 LRGEMFFTNQ---LKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLE 1740
G++FFT+ K+E MDG NR LV++ GI +D+ ++ VYW D +D +E
Sbjct: 333 AMGKVFFTDYGQIPKVERCDMDGQNRTKLVDSKIVFPHGITLDLVSRLVYWADAYLDYIE 392
Query: 1741 SIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTD------WTRLGVIQVEKFGSDTKL 1902
+DY+G R+ + QG+ ++ H +GL +F+ YLY T+ + VI+V +F S
Sbjct: 393 VVDYEGKGRQTIIQGI-LIEHLYGLTVFENYLYATNSDNANAQQKTSVIRVNRFNSTEYQ 451
Query: 1903 LWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVG 2082
+ + + + YH QP C + P C +C+L+ +
Sbjct: 452 VVTRVDKG---GALHIYHQRRQPRVRSHACENDQYGKP---GGCSDICLLANSH----KA 501
Query: 2083 YKCACPIGQKL-VNGKRCIDSIDYLLFSSNK----IVRGIFPEINEKALAEAVLPISPIS 2247
C C G L +GK C L K I+RG+ ++ K E ++PI +
Sbjct: 502 RTCRCRSGFSLGSDGKSCKKPEHELFLVYGKGRPGIIRGM--DMGAKVPDEHMIPIENLM 559
Query: 2248 QRRIGMYFEVECDVHGNS--FFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWI 2421
R D H + ++AD I R + DG +L + ++ DW+
Sbjct: 560 NPR-------ALDFHAETGFIYFADTTSYLIGRQKIDGTERETILKDGIHNVEGVAVDWM 612
Query: 2422 SKQLYYVDN-IRNSLEVVKIGETGLVHPDELVRRQLIT-ELRDPVSVVVHPWKGLLFYAE 2595
LY+ D+ + ++ V ++ + R+ LI ++ P ++VV P G +++ +
Sbjct: 613 GDNLYWTDDGPKKTISVARLEKAA------QTRKTLIEGKMTHPRAIVVDPLNGWMYWTD 666
Query: 2596 ------AMRPAAIYRCHIDGQNCQV-IRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCM 2754
R + R +DG + + + + T+ P+ +++D RL W D I +
Sbjct: 667 WEEDPKDSRRGRLERAWMDGSHRDIFVTSKTVLWPNGLSLDIPAGRLYWVDAFYDRIETI 726
Query: 2755 DFDG--KNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADE 2928
+G + +V + + Y+++ R S+ R+ + GG V ++
Sbjct: 727 LLNGTDRKIVYEGPELNHAFGLCHHGNYLFWTEYRSGSVYRLERGVGGAPPTVTLLRSER 786
Query: 2929 RSIFSLKACSHQNQPIPDDSREHPCRASQ--CTQLCFATPSESHPNELEAKCACRQGFMI 3102
IF ++ Q Q + + CR + C+ LC ATP +CAC + ++
Sbjct: 787 PPIFEIRMYDAQQQQVGTNK----CRVNNGGCSSLCLATPG-------SRQCACAEDQVL 835
Query: 3103 NKENNHSCQKDPAEKIEQLCSSNSTQFQCKNGRCIPKEWKCDGENDCLDESDEIDEKGDK 3282
+ + +C +P+ C +F C N RCI + WKCDG+NDCLD SDE
Sbjct: 836 DAD-GVTCLANPSYVPPPQCQPG--EFACANSRCIQERWKCDGDNDCLDNSDE----APA 888
Query: 3283 CFHETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCD 3462
H+ C + KC N +CIP + C C +F C
Sbjct: 889 LCHQHTCPSDRFKCEN-NRCIPNRWLCDGDNDCGNSEDESNATC---SARTCPPNQFSCA 944
Query: 3463 NHRCIPEQWKXXXXXXXXXXXXEKLEMCGNATC-AANQFSCANGRCIPIYWLCDGDNDCY 3639
+ RCIP W E C TC QF+C NGRCI I W CD DNDC
Sbjct: 945 SGRCIPISWTCDLDDDCGDRSDESAS-CAYPTCFPLTQFTCNNGRCININWRCDNDNDCG 1003
Query: 3640 DGTDEDKERCPPVQCSALQFRCANGRQCVPLR------NHXXXXXXXXXXXXXXXXAVTA 3801
D +DE C CS+ QF+C +GR C+P N
Sbjct: 1004 DNSDE--AGCSH-SCSSTQFKCNSGR-CIPEHWTCDGDNDCGDYSDETHANCTNQATRPP 1059
Query: 3802 ESCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKC-GNGRCI 3978
C D+F+C GLCIP W+ SDE + S +F C + RCI
Sbjct: 1060 GGCHTDEFQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPSVKFGCKDSARCI 1119
Query: 3979 LNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDGKTHC 4158
W+CDG+NDC D SDE + C+ S+ R P H C N+ C+P +LCDG C
Sbjct: 1120 SKAWVCDGDNDCEDNSDEEN---CE-SLACR--PPSH-PCANNTSVCLPPDKLCDGNDDC 1172
Query: 4159 PGGTDEGGRCARDLCSADRAGCSFKCHNSP-NGPICSCPFGEQL-VNKTKCEPENECLDS 4332
G+DEG C D CS + GCS C +P G +CSCP G +L + C+ ++ C
Sbjct: 1173 GDGSDEGELC--DQCSLNNGGCSHNCSVAPGEGIVCSCPLGMELGPDNHTCQIQSYCAKH 1230
Query: 4333 SSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNW 4512
CSQ+C K CSC EG+ L+ D +C+ D K I+ SNR+ I D ++
Sbjct: 1231 LKCSQKCDQNKFSVKCSCYEGWVLEPDGESCRSLDPFKPFIIF-SNRHEIRRIDLHKGDY 1289
Query: 4513 HTFGAIVENAIALAWDSLTDRIYWSDIREKKI----LSANRNGTNATVFIADGLDITEGI 4680
+ N IAL + +YW+D+ E KI L N T+ V I GL EG+
Sbjct: 1290 SVLVPGLRNTIALDFHLSQSALYWTDVVEDKIYRGKLLDNGALTSFEVVIQYGLATPEGL 1349
Query: 4681 ALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQ 4860
A+DW+ N+YWV+S+L+ IEVA L D RT L+ ++ PR IA+DPR G++FWTDW
Sbjct: 1350 AVDWIAGNIYWVESNLDQIEVAKL-DGTLRTTLLAGDIEHPRAIALDPRDGILFWTDWDA 1408
Query: 4861 N-PCIERASMDGTDRQIIVKT--KIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGR 5031
+ P IE ASM G R+ + + WPN + +DY R+ + D++ D I YDGSG
Sbjct: 1409 SLPRIEAASMSGAGRRTVHRETGSGGWPNGLTVDYLEKRILWIDARSDAIYSARYDGSGH 1468
Query: 5032 TQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVA 5211
+VL +F+ HP A+ ++ +Y++D R L K+ G T ++ +
Sbjct: 1469 MEVLRGHEFLSHPFAVTLYGGEVYWTDWRTNTLAKANKW-TGHNVTVVQRTNTQPFDLQV 1527
Query: 5212 VHPVLQPVIKNNPCSTN----PCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKPFL 5379
HP QP+ NPC N PCSHLCL+N T +C CP KL C + K FL
Sbjct: 1528 YHPSRQPMAP-NPCEANGGQGPCSHLCLINYNRTVSCACPHLMKLHKDNTTCY-EFKKFL 1585
Query: 5380 VIIQKTNVFGIEMNSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTL 5559
+ ++ + G+++++ +++ VP + N YDA + ++ +
Sbjct: 1586 LYARQMEIRGVDLDAPYYNY--IISFTVP--DIDNVTVLDYDAREQRVYWSD-------- 1633
Query: 5560 AQITTDSAIYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKIT--QTIEIIRT 5733
AI R+ +NG + S+ +P +A+ L DW RNL + T + I + R
Sbjct: 1634 ---VRTQAIKRAFINGTGVETVVSADLP-NAHGLAVDWVSRNLFWTSYDTNKKQINVARL 1689
Query: 5734 QGKQYRSVILSNDQSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLV 5913
G +V+ +Q +G ++W D ++ A +DGSN +
Sbjct: 1690 DGSFKNAVVQGLEQP-------HGLVVHPLRGKLYWTD------GDNISMANMDGSNRTL 1736
Query: 5914 IASNDLAELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNG----LA 6081
+ S + +AID +++Y+ + I+ DG + D R G LA
Sbjct: 1737 LFSGQKGPVG-LAIDFPESKLYWISSGNHTINRCNLDGSGLEVI--DAMRSQLGKATALA 1793
Query: 6082 FYGDRLFYADSAFDSIEVATINGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHIN 6261
GD+L++AD + + + S + V ++ +PC +N
Sbjct: 1794 IMGDKLWWADQVSEKMGTCSKADGSGSVVLRNSTTLVMHMKVYDESIQLDHKGTNPCSVN 1853
Query: 6262 NGNCDHICIPLMFAQRTCTCANGY-VKDGQTSCKLFDESFVIVATKTKVIGYPIDETQSK 6438
NG+C +C+P R+C C GY ++ GQ +C+ SF++ + + G P+D K
Sbjct: 1854 NGDCSQLCLPTSETTRSCMCTAGYSLRSGQQACEGVG-SFLLYSVHEGIRGIPLD-PNDK 1911
Query: 6439 GVAMEPIGGLSI-TGVDYDYESKTIYVAE--ASGINKGITAYTIGESSPRAVIRDSIGSL 6609
A+ P+ G S+ G+D+ E+ TIY + S I++ T E V+ + IG
Sbjct: 1912 SDALVPVSGTSLAVGIDFHAENDTIYWVDMGLSTISRAKRDQTWRED----VVTNGIG-- 1965
Query: 6610 TIKSLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLY 6789
++ +A+DWI N+Y+ + + IEV++L+G++R ++++ + P +I V P YL+
Sbjct: 1966 RVEGIAVDWIAGNIYWTDQGFD--VIEVARLNGSFRYVVISQGLDKPRAITVHPEKGYLF 2023
Query: 6790 WADQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRV-RST 6966
W + GQ P I+RS LDG+ R V+V+ I+ P + VD +YW DA+ D I R+ T
Sbjct: 2024 WTEWGQYPRIERSRLDGTERVVLVNVSISWPNGISVDYQDGKLYWCDARTDKIERIDLET 2083
Query: 6967 GGTPELV-RSDIASAAGVALHGQNMYWTD-NRLEKLFRATSKPNQTSLLLSPTTVAASLK 7140
G E+V S+ V++ +YW+D + SK N T + T + LK
Sbjct: 2084 GENREVVLSSNNMDMFSVSVFEDFIYWSDRTHANGSIKRGSKDNATDSVPLRTGIGVQLK 2143
Query: 7141 DIGDVAVFSSNNQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCARGVL--KGRTC 7314
DI VF+ + Q + ++ C + + C QLC G C+CA G+L G +C
Sbjct: 2144 DI---KVFNRDRQ-KGTNVCAVAN----GGCQQLCLYR-GRGQRACACAHGMLAEDGASC 2194
Query: 7315 EEPDTYIMFSDGDKIIDVAIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPV 7494
E Y+++S+ + + + + + P++ PF + +++ + L Y SP
Sbjct: 2195 REYAGYLLYSERTILKSIHLSDERNLNAPVQ-PFEDPEHMKNV---IALAFDYRAGTSPG 2250
Query: 7495 GVNISWFSMNNAENPRLV--FGASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVM-- 7662
N +FS + N + + G+ + + + + + +Y+T+ +
Sbjct: 2251 TPNRIFFSDIHFGNIQQINDDGSRRITIVENVGSVEGLAYHRGWDTLYWTSYTTSTITRH 2310
Query: 7663 AIDTA------GEHLSTIASGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLA 7824
+D E + T++ D A +D C L+FW T+ P I R+ L+
Sbjct: 2311 TVDQTRPGAFERETVITMSGDDHPRAFVLDECQNLMFW------TNWNEQHPSIMRAALS 2364
Query: 7825 GGSRKVIVSESISLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVI--ASGYRAKS 7998
G + ++ + I P +A+D R +K+Y++D IE +YDG +R VI +
Sbjct: 2365 GANVLTLIEKDIRTPNGLAIDHRAEKLYFSDATLDKIERCEYDGSHRYVILKSEPVHPFG 2424
Query: 7999 LDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVSDRRIP-GALRVFASESDVRTRNQVCN 8175
L ++ ++ +D + V R +K GS ++ + D IP + + A +D N
Sbjct: 2425 LAVYGEHIFWTDWVRRAVQRANKHVGSNMKLLRVD--IPQQPMGIIAVANDT-------N 2475
Query: 8176 ALTSQLCKTDNGGCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSN 8355
+ C+ +NGGC LC + V CSC G+ R N
Sbjct: 2476 SCELSPCRINNGGCQDLCLLTHQ------GHVNCSCRG--------GRILQDDLTCRAVN 2521
Query: 8356 SEPAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRR 8535
S C F+C +G CI TCD P C D SDE P+YCN+R C + + C+N R
Sbjct: 2522 S----SCRAQDEFECANGECINFSLTCDGVPHCKDKSDEKPSYCNSRRCKKTFRQCSNGR 2577
Query: 8536 CIDSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVS 8715
C+ + CN DDCGDGSDE+ C + AC G F C +G CI + C+ DC D S
Sbjct: 2578 CVSNMLWCNGADDCGDGSDEIPC-NKTACGVGEFRCRDGTCIGNSSRCNQFVDCED--AS 2634
Query: 8716 DE---SLATCPG-LPIDCRGVKVR-CPNTNICIQPADLCDGYDDCGDKADENQLFCMNQ- 8877
DE S C + +GV + C T++C P+ +CDG +DCGD +DE + +
Sbjct: 2635 DEMNCSATDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDERDCPGVKRP 2694
Query: 8878 QCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKC 9057
+C +Y CPSGRCIP +W CD ++DC G DETH N K C + F+C N +C
Sbjct: 2695 RCPLNYFACPSGRCIPMSWTCDKEDDCEHGEDETHCN-------KFC-SEAQFECQNHRC 2746
Query: 9058 ISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGD 9237
IS+ ++ + C +TC F C + C+P WLCDGD
Sbjct: 2747 ISKQWLCDGSDDCGDGSDEAAH--CEGKTCGPSSFSCPGT-------HVCVPERWLCDGD 2797
Query: 9238 VTCAGGEDESTELCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSS 9417
CA G DES C+ EF C N+ CI + CD D DC DGSDE C Y +
Sbjct: 2798 KDCADGADESIAAGCLYNSTCDDREFMCQNRQCIPKHFVCDHDRDCADGSDESPECEYPT 2857
Query: 9418 CQPDFFQCANHKCVPN-SWKCDGNDDCEDGSDEKDCPKNSASAQKASKC-SNGQFQCTSG 9591
C P F+CAN +C+ + W+CDG +DC D SDE PKN KC ++ QF C+SG
Sbjct: 2858 CGPSEFRCANGRCLSSRQWECDGENDCHDQSDE--APKNPHCTSPEHKCNASSQFLCSSG 2915
Query: 9592 ECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAID 9771
C+ +A +C+ DC D SDE C I+EC + C Q C D+KIG+KC C GF +
Sbjct: 2916 RCVAEALLCNGQDDCGDSSDERG-CHINECLSRKLSGCSQDCEDLKIGFKCRCRPGFRLK 2974
Query: 9772 ISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGY-QLSSDDHSCKRTEMEPEPFF 9948
D ++C +V+EC CSQ+C + GSYKC CV+GY D HSCK E EPF
Sbjct: 2975 -DDGRTCADVDECSTTFP-CSQRCINTHGSYKCLCVEGYAPRGGDPHSCKAVTDE-EPFL 3031
Query: 9949 LLANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLID---QGKLRLLRVDLDE 10119
+ AN++Y+RK+++DG+ Y L QG +N V+LD D E+ Y D QG + + R+ L+
Sbjct: 3032 IFANRYYLRKLNLDGSNYTLLKQGLNNAVALDFDYREQMIYWTDVTTQGSM-IRRMHLNG 3090
Query: 10120 MDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQ 10299
S+ + + R + +G+AVDWVG LY ++ +I V +L+G + L+ ++
Sbjct: 3091 -----SNVQVLHRTGLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVSSGLR 3145
Query: 10300 QPKAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFS 10479
+P+A+VV GYL++T+W IGRI +DGS + + + WPN + +DY +
Sbjct: 3146 EPRALVVDVQNGYLYWTDWGDHSLIGRIGMDGSSR-----SVIVDTKITWPNGLTLDYVT 3200
Query: 10480 DRLFWGDAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKW 10659
+R++W DA + I F DG+ R + +Q H+ ++ +F+DY+YW DW + + R K
Sbjct: 3201 ERIYWADAREDYIEFASLDGSNRHVVLSQDIPHIFALTLFEDYVYWTDWETKSINRAHKT 3260
Query: 10660 TGKNETILKKTVQLPNDLRIVHPMRQPAYPN-PCGDNNGGCSHLCLIGAGGNGYTCSCPD 10836
TG N+T+L T+ P DL + H +RQP PN PC NNGGCS+LCL+ GG G+ C+CP
Sbjct: 3261 TGTNKTLLISTLHRPMDLHVFHALRQPDVPNHPCKVNNGGCSNLCLLSPGG-GHKCACPT 3319
Query: 10837 QFVLLSDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICP 11016
F L SD +TC NCT QF C D KCIP W CD E DC D SDEP + C + C
Sbjct: 3320 NFYLGSDGRTCVSNCTASQFVCKND--KCIPFWWKCDTEDDCGDHSDEPPD--CPEFKCR 3375
Query: 11017 VGEFQCTNHNCTRPFQIXXXXXXXXXXXXEQNCD-KACDPWMFKCAATGRCIPRRFTXXX 11193
G+FQC+ CT P I E NCD C P FKC T RCIP F
Sbjct: 3376 PGQFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNG 3435
Query: 11194 XXXXXXRSDEADTLCMSAERNCTAEEFRCN-NNKCIAKAWRXXXXXXXXXXXXETPECAQ 11370
DE D E C +F+C+ +CI + W E C Q
Sbjct: 3436 QDNCGDGEDERD----CPEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQ 3491
Query: 11371 IECKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCP--TCDDVGEFRCATSGKCI 11544
+ C RC S RCIP C+G+DDC D SDE K+ C TC+ +FRC + +C+
Sbjct: 3492 MTCGVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPY-QFRC-KNNRCV 3549
Query: 11545 PRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLD 11724
P RW CD +NDCGDNSDE SC T RPCSESEF C +G+CI G CDG C+DG D
Sbjct: 3550 PGRWQCDYDNDCGDNSDE--ESC--TPRPCSESEFSCANGRCIAGRWKCDGDHDCADGSD 3605
Query: 11725 ESQCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFECAN 11904
E CT RC QC G CI CD DC + +DE C RTC EF+C N
Sbjct: 3606 EKDCT-PRCDMDQFQCKSGHCIPLRWRCDADADCMDGSDEEAC-GTGVRTCPLDEFQCNN 3663
Query: 11905 SVCIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCG 12084
++C P + SDE EC C P FRC + R+CL I + C+G ++CG
Sbjct: 3664 TLCKPLAWKCDGEDDCGDNSDENPEECARFVCPPNRPFRCKNDRVCLWIGRQCDGTDNCG 3723
Query: 12085 PNDFSDE--------HLSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDE 12240
D +DE H + C E F C N +C++ ++ C+ DDCGD SDE
Sbjct: 3724 --DGTDEEDCEPPTAHTTHCKDKKE--------FLCRNQRCLSSSLRCNMFDDCGDGSDE 3773
Query: 12241 IGCSKHGGKTSCEAFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNN 12420
CS TSC + G + C YC CR GF P P C DI+EC
Sbjct: 3774 EDCSIDPKLTSCATNASICGDEARCVRTEKAAYCACRSGFHTVPGQP-GCQDINECLRFG 3832
Query: 12421 TCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGS 12600
TC+QLC NTKG +LC C ++ T C+A+G V+ ADD+ ++ G
Sbjct: 3833 TCSQLCNNTKGGHLCSCARNF-------MKTHNTCKAEGSEYQVLYIADDNEIRSLFPGH 3885
Query: 12601 GTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERTI-YRS---AIANGNQSHEGQKL 12768
+ + + +YW + TI YRS A + +++
Sbjct: 3886 PHSAYEQAFQGDESVRIDAMDVHVKAGRVYWTNWHTGTISYRSLPPAAPPTTSNRHRRQI 3945
Query: 12769 DVDFAAMGV----VPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFI 12936
D + + +P IA+D+ GN++ ++ I
Sbjct: 3946 DRGVTHLNISGLKMPRGIAIDWVAGNVYWTDSGRDV-----------------------I 3982
Query: 12937 FVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKD 13116
V G K +++G + +P A++ P G + +SD G H KIE A MDGT R+ +V+D
Sbjct: 3983 EVAQMKGENRKTLISGMIDEPHAIVVDPLRGTMYWSDWGNHPKIETAAMDGTLRETLVQD 4042
Query: 13117 LVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRH---IPYAVDVFENH 13287
+ PT +A+D R+YW D K + ++ ++G++ + P+++DVFE++
Sbjct: 4043 NIQWPTGLAVDY-HNERLYWADAKLSVIGSIRLNGTDPIVAADSKRGLSHPFSIDVFEDY 4101
Query: 13288 IYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHL 13467
IY ++ + ++ KFG + L L H V + + C+R +C L
Sbjct: 4102 IYGVTYINNRVFKIHKFGHSPLVNLTGGL--SHASDVVLYHQHKQPEVTNPCDRKKCEWL 4159
Query: 13468 CVSLPSTGFACLCPDGIVPQLD-GSCATQHVEALTMPKQC--------KCTNGGKCRLDG 13620
C+ PS G C CP+G +LD G+C V + T P +C NGG C L+
Sbjct: 4160 CLLSPS-GPVCTCPNG--KRLDNGTCVP--VPSPTPPPDAPRPGTCNLQCFNGGSCFLNA 4214
Query: 13621 ----SCECTSDFEGDQCE 13662
C C + GD+CE
Sbjct: 4215 RRQPKCRCQPRYTGDKCE 4232
Score = 361 bits (926), Expect = 3e-97
Identities = 285/1027 (27%), Positives = 446/1027 (42%), Gaps = 27/1027 (2%)
Frame = +1
Query: 130 ASVNTASSVCNENDFRCNDGKCIRTEWX-XXXXXXXXXXXXXXXXPHPGCKSDQWQCDTY 306
++ ++ C N F C G+CI W +P C + +
Sbjct: 927 SNATCSARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPTC----FPLTQF 982
Query: 307 TWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGK 486
T ++ CI RCDN DC D SDE C S CSS F C GR C CDG
Sbjct: 983 TCNNGRCININWRCDNDNDCGDNSDEAGCSHS---CSSTQ-FKCNSGR-CIPEHWTCDGD 1037
Query: 487 YDCRDLSDEKD-SCSRNHT----ACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDT 651
DC D SDE +C+ T C +F+C CI W CDG DC D SDE +
Sbjct: 1038 NDCGDYSDETHANCTNQATRPPGGCHTDEFQCRLDGLCIPLRWRCDGDTDCMDSSDE-KS 1096
Query: 652 CEFKKCTAN---EFQCKNK-RCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCP-GT 816
CE + +F CK+ RC + + CD +DC DNSDE+ C C P C T
Sbjct: 1097 CEGVTHVCDPSVKFGCKDSARCISKAWVCDGDNDCEDNSDEENCESLACRPPSHPCANNT 1156
Query: 817 GHCIDQLKLCDGSKDCADGADE-QQCSQNLCPSLGCQAGCHPSP-HGGECTCPSGYKLDD 990
C+ KLCDG+ DC DG+DE + C Q + GC C +P G C+CP G +L
Sbjct: 1157 SVCLPPDKLCDGNDDCGDGSDEGELCDQCSLNNGGCSHNCSVAPGEGIVCSCPLGMELGP 1216
Query: 991 RFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSN 1170
H TC + CA+ C Q C ++ CSC + + L+ + G+ C S
Sbjct: 1217 DNH-TCQIQSYCAKHLKCSQKCDQNKFSVKCSCY-EGWVLEPD---GES-------CRSL 1264
Query: 1171 NADKMKLFVARREGLYRLNPKNPDEEVKKLASG-EFIYGIDFDYGDRKIFWTDRLAHSAF 1347
+ K + + R + R++ D V L G +DF ++WTD + +
Sbjct: 1265 DPFKPFIIFSNRHEIRRIDLHKGDYSV--LVPGLRNTIALDFHLSQSALYWTDVVEDKIY 1322
Query: 1348 SADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLL 1527
+ D G ++ + + L P LAVDWI +Y +ES +I+V+ DG RT LL
Sbjct: 1323 RGKLLDNGALTSFEVVIQYGLATPEGLAVDWIAGNIYWVESNLDQIEVAKLDGTLRTTLL 1382
Query: 1528 ADGLTLPLDIALDPLRGEMFFT----NQLKLEAAAMDGTNRRTLVNTHTHQ---VSGIVV 1686
A + P IALDP G +F+T + ++EAA+M G RRT V+ T +G+ V
Sbjct: 1383 AGDIEHPRAIALDPRDGILFWTDWDASLPRIEAASMSGAGRRT-VHRETGSGGWPNGLTV 1441
Query: 1687 DITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGV 1866
D KR+ W+D + D + S Y G+ V +G + HPF + L+ +YWTDW +
Sbjct: 1442 DYLEKRILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYGGEVYWTDWRTNTL 1501
Query: 1867 IQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMC 2046
+ K+ + T N P + YHP QP + C A + PC++ +C
Sbjct: 1502 AKANKWTGHNVTVVQRT--NTQPFDLQVYHPSRQP-MAPNPCEANGGQGPCSH-----LC 1553
Query: 2047 ILSKDNGGFGVGYKCACPIGQKL-VNGKRCIDSIDYLLFSSNKIVRGIFPEINEKALAEA 2223
+++ + CACP KL + C + +LL++ +RG+ + A
Sbjct: 1554 LIN-----YNRTVSCACPHLMKLHKDNTTCYEFKKFLLYARQMEIRGVDLD------APY 1602
Query: 2224 VLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFS 2403
I + I ++ D +++D+ I R +G G V+
Sbjct: 1603 YNYIISFTVPDIDNVTVLDYDAREQRVYWSDVRTQAIKRAFINGTGVETVVSADLPNAHG 1662
Query: 2404 MSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKGLL 2583
++ DW+S+ L++ N ++ + D + ++ L P +VVHP +G L
Sbjct: 1663 LAVDWVSRNLFWTSYDTNKKQI------NVARLDGSFKNAVVQGLEQPHGLVVHPLRGKL 1716
Query: 2584 FYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFD 2763
++ + I ++DG N ++ + G P +AIDF E++L W + TI+ + D
Sbjct: 1717 YWTDGDN---ISMANMDGSNRTLLFSGQKG-PVGLAIDFPESKLYWISSGNHTINRCNLD 1772
Query: 2764 GKNVVKLDIDNP---IPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERS 2934
G + +D A+ IM + +++ Q + K +G GS ++R
Sbjct: 1773 GSGLEVIDAMRSQLGKATALAIMGDKLWWADQVSEKMGTCSKADGSGSVVLRN---STTL 1829
Query: 2935 IFSLKACSHQNQPIPDDSREHPCRAS--QCTQLCFATPSESHPNELEAKCACRQGFMINK 3108
+ +K Q D +PC + C+QLC T +E C C G+ + +
Sbjct: 1830 VMHMKVYDESIQ--LDHKGTNPCSVNNGDCSQLCLPT------SETTRSCMCTAGYSL-R 1880
Query: 3109 ENNHSCQ 3129
+C+
Sbjct: 1881 SGQQACE 1887
Score = 323 bits (828), Expect = 8e-86
Identities = 213/683 (31%), Positives = 310/683 (45%), Gaps = 21/683 (3%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAE 336
C N F C G+CI W + C Q++C + CI++
Sbjct: 2696 CPLNYFACPSGRCIPMSWTCDKEDDCEHGEDETHC-NKFCSEAQFECQNHR-----CISK 2749
Query: 337 YQRCDNITDCADGSDEK-DCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDE 513
CD DC DGSDE C T SS F C C CDG DC D +DE
Sbjct: 2750 QWLCDGSDDCGDGSDEAAHCEGKTCGPSS---FSCPGTHVCVPERWLCDGDKDCADGADE 2806
Query: 514 KDS--CSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQ 687
+ C N T C +F C ++ QCI K +VCD +DCADGSDE CE+ C +EF+
Sbjct: 2807 SIAAGCLYNST-CDDREFMCQNR-QCIPKHFVCDHDRDCADGSDESPECEYPTCGPSEFR 2864
Query: 688 CKNKRC-QPRKFRCDYYDDCGDNSDE----DEC--GEYRCPPGKWNCPGTGHCIDQLKLC 846
C N RC R++ CD +DC D SDE C E++C +G C+ + LC
Sbjct: 2865 CANGRCLSSRQWECDGENDCHDQSDEAPKNPHCTSPEHKCNASSQFLCSSGRCVAEALLC 2924
Query: 847 DGSKDCADGADEQQCSQNLCPS---LGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDI 1017
+G DC D +DE+ C N C S GC C G +C C G++L D RTC+D+
Sbjct: 2925 NGQDDCGDSSDERGCHINECLSRKLSGCSQDCEDLKIGFKCRCRPGFRLKDD-GRTCADV 2983
Query: 1018 NECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRG----YCVSNNADKM 1185
+EC+ C Q C N + C C+ + RG C + ++
Sbjct: 2984 DECSTTFPCSQRCINTHGSYKCLCV--------------EGYAPRGGDPHSCKAVTDEEP 3029
Query: 1186 KLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDD 1365
L A R L +LN + + K + +DFDY ++ I+WTD + +
Sbjct: 3030 FLIFANRYYLRKLNLDGSNYTLLKQGLNNAV-ALDFDYREQMIYWTDVTTQGSMIRRMHL 3088
Query: 1366 EGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTL 1545
G S ++ L L P LAVDW+ LY + G I+VS +G RTVL++ GL
Sbjct: 3089 NG--SNVQVLHRTGLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVSSGLRE 3146
Query: 1546 PLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWV 1716
P + +D G +++T + + MDG++R +V+T +G+ +D +R+YW
Sbjct: 3147 PRALVVDVQNGYLYWTDWGDHSLIGRIGMDGSSRSVIVDTKITWPNGLTLDYVTERIYWA 3206
Query: 1717 DPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFGSDT 1896
D + D +E G++R +V +PH F L LF+ Y+YWTDW + + K
Sbjct: 3207 DAREDYIEFASLDGSNRHVVLS--QDIPHIFALTLFEDYVYWTDWETKSINRAHKTTGTN 3264
Query: 1897 KLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFG 2076
K L +T + PM + +H + QP C N C +C+LS G
Sbjct: 3265 KTLLISTLHR--PMDLHVFHALRQPDVPNHPC-------KVNNGGCSNLCLLSP-----G 3310
Query: 2077 VGYKCACPIGQKL-VNGKRCIDS 2142
G+KCACP L +G+ C+ +
Sbjct: 3311 GGHKCACPTNFYLGSDGRTCVSN 3333
Score = 316 bits (809), Expect = 1e-83
Identities = 220/745 (29%), Positives = 321/745 (42%), Gaps = 83/745 (11%)
Frame = +1
Query: 139 NTASSVCNENDFRCND-GKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWH 315
N C ++FRC D G+CI W P + D+ C+ Y +
Sbjct: 3488 NCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDGSD-----EPKEECDERTCEPYQFR 3542
Query: 316 SVS--CIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKY 489
+ C+ +CD DC D SDE+ C T S++ F CA+GR C KCDG +
Sbjct: 3543 CKNNRCVPGRWQCDYDNDCGDNSDEESC---TPRPCSESEFSCANGR-CIAGRWKCDGDH 3598
Query: 490 DCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCE--FK 663
DC D SDEKD R C QF+C CI W CD DC DGSDE + C +
Sbjct: 3599 DCADGSDEKDCTPR----CDMDQFQCKSG-HCIPLRWRCDADADCMDGSDE-EACGTGVR 3652
Query: 664 KCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDE--DECGEYRCPPGK-WNCPGTGHCIDQ 834
C +EFQC N C+P ++CD DDCGDNSDE +EC + CPP + + C C+
Sbjct: 3653 TCPLDEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEECARFVCPPNRPFRCKNDRVCLWI 3712
Query: 835 LKLCDGSKDCADGADEQQCS-------------QNLCPSLGC------------------ 921
+ CDG+ +C DG DE+ C + LC + C
Sbjct: 3713 GRQCDGTDNCGDGTDEEDCEPPTAHTTHCKDKKEFLCRNQRCLSSSLRCNMFDDCGDGSD 3772
Query: 922 ----------------------QAGCHPSPHGGECTCPSGYKLDDRFHRT-----CSDIN 1020
+A C + C C SG FH C DIN
Sbjct: 3773 EEDCSIDPKLTSCATNASICGDEARCVRTEKAAYCACRSG------FHTVPGQPGCQDIN 3826
Query: 1021 ECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVA 1200
EC FG C QLC N + G CSC ++ + C + ++ L++A
Sbjct: 3827 ECLRFGTCSQLCNNTKGGHLCSC-------------ARNFMKTHNTCKAEGSEYQVLYIA 3873
Query: 1201 RREGLYRLNPKNPDEEVKKLASGEF---IYGIDFDYGDRKIFWTD----RLAHSAF---S 1350
+ L P +P ++ G+ I +D +++WT+ +++ + +
Sbjct: 3874 DDNEIRSLFPGHPHSAYEQAFQGDESVRIDAMDVHVKAGRVYWTNWHTGTISYRSLPPAA 3933
Query: 1351 ADVDDEGEISQIKK----LSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRT 1518
QI + L++ L PR +A+DW+ +Y +SG I+V+ GE R
Sbjct: 3934 PPTTSNRHRRQIDRGVTHLNISGLKMPRGIAIDWVAGNVYWTDSGRDVIEVAQMKGENRK 3993
Query: 1519 VLLADGLTLPLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVD 1689
L++ + P I +DPLRG M+++ N K+E AAMDGT R TLV + +G+ VD
Sbjct: 3994 TLISGMIDEPHAIVVDPLRGTMYWSDWGNHPKIETAAMDGTLRETLVQDNIQWPTGLAVD 4053
Query: 1690 ITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVI 1869
+R+YW D K+ + SI G D + A + HPF + +F+ Y+Y + V
Sbjct: 4054 YHNERLYWADAKLSVIGSIRLNGTDPIVAADSKRGLSHPFSIDVFEDYIYGVTYINNRVF 4113
Query: 1870 QVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCI 2049
++ KFG L + T + YH QP ++ NPC CE +C+
Sbjct: 4114 KIHKFGHSP--LVNLTGGLSHASDVVLYHQHKQP----------EVTNPCDRKKCEWLCL 4161
Query: 2050 LSKDNGGFGVGYKCACPIGQKLVNG 2124
LS G C CP G++L NG
Sbjct: 4162 LSPS------GPVCTCPNGKRLDNG 4180
Score = 178 bits (451), Expect = 4e-42
Identities = 90/247 (36%), Positives = 125/247 (50%), Gaps = 1/247 (0%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAE 336
C F+C+ G C + C Q++C ++ CI
Sbjct: 3374 CRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCT----NTNRCIPG 3429
Query: 337 YQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEK 516
RC+ +C DG DE+DCP T + N F C+ ++C CD DC D SDE
Sbjct: 3430 IFRCNGQDNCGDGEDERDCPEVTC---APNQFQCSITKRCIPRVWVCDRDNDCVDGSDEP 3486
Query: 517 DSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEP-DTCEFKKCTANEFQCK 693
+C++ C +FRC D +CI W CDG DC DGSDEP + C+ + C +F+CK
Sbjct: 3487 ANCTQ--MTCGVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCK 3544
Query: 694 NKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADG 873
N RC P +++CDY +DCGDNSDE+ C C +++C G CI CDG DCADG
Sbjct: 3545 NNRCVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFSC-ANGRCIAGRWKCDGDHDCADG 3603
Query: 874 ADEQQCS 894
+DE+ C+
Sbjct: 3604 SDEKDCT 3610
Score = 167 bits (423), Expect = 7e-39
Identities = 143/604 (23%), Positives = 237/604 (38%), Gaps = 26/604 (4%)
Frame = +1
Query: 9139 RTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEK-KECNKGEF 9315
+TC+ ++F C + + CI + W CDG+ C G DE+ E+C K + C E
Sbjct: 25 KTCSPKQFAC-------RDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEH 77
Query: 9316 RC-SNQHCIHSTWECDGDNDCLDGSDE-------HANCTYSSCQPDFFQCANHKCVPNSW 9471
C + C+ + C+G DC+DGSDE NC+ CQ H CVP
Sbjct: 78 NCLGTELCVPMSRLCNGVQDCMDGSDEGPHCRELQGNCSRLGCQ--------HHCVPT-- 127
Query: 9472 KCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSD 9651
D C NS+ +A D K C ++F
Sbjct: 128 -----------LDGPTCYCNSSFQLQA-----------------DGKTC-KDF------- 151
Query: 9652 ESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNECYEGISGC 9831
DECS+ C Q C + + C C EG+ + D +SC NE
Sbjct: 152 -------DECSV--YGTCSQLCTNTDGSFICGCVEGYLLQ-PDNRSCKAKNE-------- 193
Query: 9832 SQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYE-L 10008
++ P L+AN I + G + +
Sbjct: 194 -------------------------------PVDRPPVLLIANSQNILATYLSGAQVSTI 222
Query: 10009 AAQGFDNVVSLDIDLTEKKAYLIDQG----KLRLLRVDLDEMDSPLSSYETVLRHNVYGT 10176
++D + + G + +L + + + + + +++
Sbjct: 223 TPTSTRQTTAMDFSYANETVCWVHVGDSAAQTQLKCARMPGLKGFVDEHTINISLSLHHV 282
Query: 10177 EGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFFTEW 10356
E +A+DW+ Y ++ + I VC +G C TL+ + PK I + P G +FFT++
Sbjct: 283 EQMAIDWLTGNFYFVDDIDDRIFVCNRNGDTCVTLLDLELYNPKGIALDPAMGKVFFTDY 342
Query: 10357 SLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFD 10536
P + R +DG KL + + +P+ I +D S ++W DA+L+ I +D++
Sbjct: 343 GQIPKVERCDMDGQNRT-----KLVDSKIVFPHGITLDLVSRLVYWADAYLDYIEVVDYE 397
Query: 10537 GNGRRH-IPAQRTSHVSSMVVFDDYLYWAD------WNLREVLRCDKWTGKNETILKKTV 10695
G GR+ I H+ + VF++YLY + V+R +++ ++ + V
Sbjct: 398 GKGRQTIIQGILIEHLYGLTVFENYLYATNSDNANAQQKTSVIRVNRFNSTEYQVVTR-V 456
Query: 10696 QLPNDLRIVHPMRQPAYPNPCGDNN-----GGCSHLCLIGAGGNGYTCSCPDQFVLLSDQ 10860
L I H RQP + +N+ GGCS +CL+ TC C F L SD
Sbjct: 457 DKGGALHIYHQRRQPRVRSHACENDQYGKPGGCSDICLLANSHKARTCRCRSGFSLGSDG 516
Query: 10861 KTCE 10872
K+C+
Sbjct: 517 KSCK 520
Score = 152 bits (383), Expect = 3e-34
Identities = 172/699 (24%), Positives = 258/699 (36%), Gaps = 110/699 (15%)
Frame = +1
Query: 148 SSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQ--CDTY----T 309
SS +++F C +G+CI PH KSD+ C++ T
Sbjct: 2522 SSCRAQDEFECANGECIN------------FSLTCDGVPHCKDKSDEKPSYCNSRRCKKT 2569
Query: 310 WHSVS---CIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCD 480
+ S C++ C+ DC DGSDE C + F C DG C S +C+
Sbjct: 2570 FRQCSNGRCVSNMLWCNGADDCGDGSDEIPCNKTACGVGE---FRCRDGT-CIGNSSRCN 2625
Query: 481 GKYDCRDLSDEKDSCSRNHTACFQYQFR------CADKTQCIQKSWVCDGSKDCADGSDE 642
DC D SDE + + + ++ F+ + C + C SWVCDG+ DC D SDE
Sbjct: 2626 QFVDCEDASDEMNCSATDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDE 2685
Query: 643 PDTCEFKK--CTANEFQCKNKRCQPRKFRCDYYDDCGDNSDE------------------ 762
D K+ C N F C + RC P + CD DDC DE
Sbjct: 2686 RDCPGVKRPRCPLNYFACPSGRCIPMSWTCDKEDDCEHGEDETHCNKFCSEAQFECQNHR 2745
Query: 763 -----------DECGE----------YRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGAD 879
D+CG+ C P ++CPGT C+ + LCDG KDCADGAD
Sbjct: 2746 CISKQWLCDGSDDCGDGSDEAAHCEGKTCGPSSFSCPGTHVCVPERWLCDGDKDCADGAD 2805
Query: 880 EQ---QCSQN--------LCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINEC 1026
E C N +C + C H +C S + + TC
Sbjct: 2806 ESIAAGCLYNSTCDDREFMCQNRQCIPKHFVCDHDRDCADGSDESPECEY-PTCGP---- 2860
Query: 1027 AEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARR 1206
+EF + C + R + C DC Q + P + T + NA L + R
Sbjct: 2861 SEFRCANGRCLSSRQ-WECDGENDCHD-QSDEAPKNPHCTSPEH--KCNASSQFLCSSGR 2916
Query: 1207 EGLYRLNPKNPDE----------EVKKLASGEFIYGIDFDYGDRKIFWTDRLA------- 1335
L D+ + + S + + G D D KI + R
Sbjct: 2917 CVAEALLCNGQDDCGDSSDERGCHINECLSRK-LSGCSQDCEDLKIGFKCRCRPGFRLKD 2975
Query: 1336 HSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWIT--------------NTLYIIESG 1473
ADVD+ + + + +CL V+ ++I +
Sbjct: 2976 DGRTCADVDECSTTFPCSQRCINTHGSYKCLCVEGYAPRGGDPHSCKAVTDEEPFLIFAN 3035
Query: 1474 SRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTNQLKLEAAA-----MDGTNR 1638
+ + DG T LL GL + + D R +M + + + + ++G+N
Sbjct: 3036 RYYLRKLNLDGSNYT-LLKQGLNNAVALDFD-YREQMIYWTDVTTQGSMIRRMHLNGSNV 3093
Query: 1639 RTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLA 1818
+ L T G+ VD +YW D D +E G R ++ P +
Sbjct: 3094 QVLHRTGLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVSSGLREPRALVVD 3153
Query: 1819 LFDQYLYWTDWTRLGVI-QVEKFGS------DTKLLWSN 1914
+ + YLYWTDW +I ++ GS DTK+ W N
Sbjct: 3154 VQNGYLYWTDWGDHSLIGRIGMDGSSRSVIVDTKITWPN 3192
Score = 143 bits (360), Expect = 1e-31
Identities = 89/293 (30%), Positives = 128/293 (43%), Gaps = 40/293 (13%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDE-KDCP----------ASTVDCSS 420
C + Q+ C + CI + +CD DC D SDE DCP ST C++
Sbjct: 3334 CTASQFVCK-----NDKCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQFQCSTGICTN 3388
Query: 421 --------------------------QNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDS 522
+ F C + +C +C+G+ +C D DE+D
Sbjct: 3389 PAFICDGDNDCQDNSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDC 3448
Query: 523 CSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNK- 699
C QF+C+ +CI + WVCD DC DGSDEP C C +EF+CK+
Sbjct: 3449 ---PEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDEFRCKDSG 3505
Query: 700 RCQPRKFRCDYYDDCGDNSDE--DECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADG 873
RC P +++CD DDCGD SDE +EC E C P ++ C C+ CD DC D
Sbjct: 3506 RCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCK-NNRCVPGRWQCDYDNDCGDN 3564
Query: 874 ADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAE 1032
+DE+ C+ C E +C +G + R+ C ++CA+
Sbjct: 3565 SDEESCTPRPCSE-------------SEFSCANGRCIAGRW--KCDGDHDCAD 3602
Score = 132 bits (333), Expect = 2e-28
Identities = 84/242 (34%), Positives = 106/242 (43%), Gaps = 14/242 (5%)
Frame = +1
Query: 430 FMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCD 609
F CA+ R C KCDG DC D SDE + HT C +F+C + +CI W+CD
Sbjct: 859 FACANSR-CIQERWKCDGDNDCLDNSDEAPALCHQHT-CPSDRFKC-ENNRCIPNRWLCD 915
Query: 610 GSKDCADGSDEPD-TCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDED-ECGEYR 783
G DC + DE + TC + C N+F C + RC P + CD DDCGD SDE C
Sbjct: 916 GDNDCGNSEDESNATCSARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPT 975
Query: 784 CPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECT 963
C P G CI+ CD DC D +DE AGC S +
Sbjct: 976 CFPLTQFTCNNGRCININWRCDNDNDCGDNSDE--------------AGCSHSCSSTQFK 1021
Query: 964 CPSGYKLDDRFHRTCSDINECAEFGYCDQLCAN------------HRPGFTCSCLGDCFT 1107
C SG + + H TC N+C + Y D+ AN H F C G C
Sbjct: 1022 CNSGRCIPE--HWTCDGDNDCGD--YSDETHANCTNQATRPPGGCHTDEFQCRLDGLCIP 1077
Query: 1108 LQ 1113
L+
Sbjct: 1078 LR 1079
Score = 127 bits (320), Expect = 6e-27
Identities = 89/264 (33%), Positives = 126/264 (47%), Gaps = 11/264 (4%)
Frame = +1
Query: 343 RCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDS 522
+C T+ GSD + C ++ C++ F+C + + C KCD + DC D SDE
Sbjct: 3314 KCACPTNFYLGSDGRTCVSN---CTASQ-FVCKNDK-CIPFWWKCDTEDDCGDHSDEPPD 3368
Query: 523 CSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKN-K 699
C C QF+C+ C +++CDG DC D SDE + C+ C ++F+C N
Sbjct: 3369 CPE--FKCRPGQFQCSTGI-CTNPAFICDGDNDCQDNSDEAN-CDIHVCLPSQFKCTNTN 3424
Query: 700 RCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGAD 879
RC P FRC+ D+CGD DE +C E C P ++ C T CI ++ +CD DC DG+D
Sbjct: 3425 RCIPGIFRCNGQDNCGDGEDERDCPEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSD 3484
Query: 880 E-QQCSQNLC--PSLGCQ--AGCHPS--PHGGECTCPSGYKLDDRFHRTCSDINECAEFG 1038
E C+Q C C+ C P+ GE C G D C D C +
Sbjct: 3485 EPANCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDG---SDEPKEEC-DERTCEPYQ 3540
Query: 1039 YCDQLCANHR--PG-FTCSCLGDC 1101
+ C N+R PG + C DC
Sbjct: 3541 F---RCKNNRCVPGRWQCDYDNDC 3561
Score = 119 bits (297), Expect = 3e-24
Identities = 155/619 (25%), Positives = 233/619 (37%), Gaps = 29/619 (4%)
Frame = +1
Query: 7198 CQ-ITDNLRKSPCTQLCFATPGTQTPTCSCARGVLKGR-TC--EEPDTYIMFSDGDKIID 7365
CQ I + LR C+QLC T G CSCAR +K TC E + +++ D I
Sbjct: 3822 CQDINECLRFGTCSQLCNNTKGGHL--CSCARNFMKTHNTCKAEGSEYQVLYIADDNEIR 3879
Query: 7366 VAIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAENPRL 7545
++ E + DV V RVY+ G IS+ S+ A P
Sbjct: 3880 SLFPGHPHSAYEQAFQGDESVRIDAMDVHVKAGRVYWT-NWHTGT-ISYRSLPPAAPP-- 3935
Query: 7546 VFGASKQPHAKEIR------HISDMKL------DWLTQKIYFTTGRGGKVMAIDTAGEHL 7689
+ H ++I +IS +K+ DW+ +Y+T + GE+
Sbjct: 3936 ---TTSNRHRRQIDRGVTHLNISGLKMPRGIAIDWVAGNVYWTDSGRDVIEVAQMKGENR 3992
Query: 7690 STIASG--DWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESIS 7863
T+ SG D +A+ +DP G ++WSD G P+IE + + G R+ +V ++I
Sbjct: 3993 KTLISGMIDEPHAIVVDPLRGTMYWSDWG-------NHPKIETAAMDGTLRETLVQDNIQ 4045
Query: 7864 LPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGYRAK----SLDIWDRWLYMS 8031
P +AVD+ N+++YWAD I +G + V A R S+D+++ ++Y
Sbjct: 4046 WPTGLAVDYHNERLYWADAKLSVIGSIRLNGTDPIVAADSKRGLSHPFSIDVFEDYIYGV 4105
Query: 8032 DPLSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNG 8211
++N VF+I K S L N+ + SDV +Q + C D
Sbjct: 4106 TYINNRVFKIHKFGHSPLVNLTGG---------LSHASDVVLYHQHKQPEVTNPC--DRK 4154
Query: 8212 GCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSEPAKECLP-PY 8388
C+ LC L+ S C+C + L D T CV S + P P
Sbjct: 4155 KCEWLCL-------LSPSGPVCTCPNGKRL------DNGT-CVPVPSPTPPPDAPRPGTC 4200
Query: 8389 NFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHI 8568
N QC +G L A K C P Y + C +C + +
Sbjct: 4201 NLQCFNGGSCFLNARRQPKCRC------QPRYTGDK--------CELDQCWEHCRNGGTC 4246
Query: 8569 DDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPGLP 8748
G CP+ + T G+C N ++ C Q + PG
Sbjct: 4247 AASPSGMPTCRCPTGFTGPKCTQQVCAGYCAN-------NSTCTVNQGNQPQCRCLPGFL 4299
Query: 8749 ID------CRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPS 8910
D C G C N C A DG C A C +C+ RC
Sbjct: 4300 GDRCQYRQCSGY---CENFGTCQMAA---DGSRQCRCTAYFEGSRCEVNKCS----RCLE 4349
Query: 8911 GRCIPETWQCDGDNDCSDG 8967
G C+ D +C+DG
Sbjct: 4350 GACVVNKQSGDVTCNCTDG 4368
Score = 106 bits (265), Expect = 1e-20
Identities = 59/172 (34%), Positives = 78/172 (45%)
Frame = +1
Query: 391 CPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCA 570
C + CS+ + G +C C + L + +C N TA QF C
Sbjct: 3294 CKVNNGGCSNLCLLSPGGGHKC-----ACPTNFY---LGSDGRTCVSNCTAS---QFVCK 3342
Query: 571 DKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGD 750
+ +CI W CD DC D SDEP C KC +FQC C F CD +DC D
Sbjct: 3343 ND-KCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQFQCSTGICTNPAFICDGDNDCQD 3401
Query: 751 NSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLC 906
NSDE C + C P ++ C T CI + C+G +C DG DE+ C + C
Sbjct: 3402 NSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTC 3453
Score = 97.1 bits (240), Expect = 1e-17
Identities = 62/185 (33%), Positives = 80/185 (42%), Gaps = 5/185 (2%)
Frame = +1
Query: 496 RDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDE-PDTCEFKKCT 672
R L D+ + N + Q +F CA+ +CI S CDG C D SDE P C ++C
Sbjct: 2509 RILQDDLTCRAVNSSCRAQDEFECANG-ECINFSLTCDGVPHCKDKSDEKPSYCNSRRCK 2567
Query: 673 ANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDG 852
QC N RC C+ DDCGD SDE C + C G++ C G CI C+
Sbjct: 2568 KTFRQCSNGRCVSNMLWCNGADDCGDGSDEIPCNKTACGVGEFRC-RDGTCIGNSSRCNQ 2626
Query: 853 SKDCADGADEQQCSQNLCPS---LGCQAGC-HPSPHGGECTCPSGYKLDDRFHRTCSDIN 1020
DC D +DE CS C S LG + P C PS C N
Sbjct: 2627 FVDCEDASDEMNCSATDCSSYFRLGVKGVLFQPCERTSLCYAPSW---------VCDGAN 2677
Query: 1021 ECAEF 1035
+C ++
Sbjct: 2678 DCGDY 2682
Score = 73.2 bits (178), Expect = 2e-10
Identities = 64/262 (24%), Positives = 111/262 (41%), Gaps = 24/262 (9%)
Frame = +1
Query: 12967 KKIVAGHLQQPTALITAPSAGRICYSD------AGLHAKIECADMDGTHRQIIVKD-LVF 13125
K ++ G + P A++ P G + ++D ++E A MDG+HR I V V
Sbjct: 640 KTLIEGKMTHPRAIVVDPLNGWMYWTDWEEDPKDSRRGRLERAWMDGSHRDIFVTSKTVL 699
Query: 13126 SPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDVFE--NHIYWL 13299
P +++D G R+YWVD Y R++ + ++G++R V + +A + N+++W
Sbjct: 700 WPNGLSLDIPAG-RLYWVDAFYDRIETILLNGTDRKIVYEGPELNHAFGLCHHGNYLFWT 758
Query: 13300 SRESKTLYVQDKFGRG---RVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLC 13470
S ++Y ++ G V++L S+ +R+ + CS LC
Sbjct: 759 EYRSGSVYRLERGVGGAPPTVTLLRSERPPIFEIRMYDAQQQQVGTNKCRVNNGGCSSLC 818
Query: 13471 VSLPSTGFACLCPDGIVPQLDG-SCATQHVEALTMPKQCK-----CTNG------GKCRL 13614
++ P + C C + V DG +C + P QC+ C N KC
Sbjct: 819 LATPGSR-QCACAEDQVLDADGVTCLAN--PSYVPPPQCQPGEFACANSRCIQERWKCDG 875
Query: 13615 DGSCECTSDFEGDQCEKESSVS 13680
D C SD C + + S
Sbjct: 876 DNDCLDNSDEAPALCHQHTCPS 897
Score = 72.4 bits (176), Expect = 3e-10
Identities = 72/311 (23%), Positives = 133/311 (42%), Gaps = 10/311 (3%)
Frame = +1
Query: 2404 MSFDWISKQLYYVDNIRNSLEVVKI-GETGLVHPDELVRRQLITELRD-PVSVVVHPWKG 2577
++ DW++ +Y+ D+ R+ +EV ++ GE R+ LI+ + D P ++VV P +G
Sbjct: 3963 IAIDWVAGNVYWTDSGRDVIEVAQMKGEN---------RKTLISGMIDEPHAIVVDPLRG 4013
Query: 2578 LLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMD 2757
+++++ I +DG + + + P+ +A+D+ RL W D L I +
Sbjct: 4014 TMYWSDWGNHPKIETAAMDGTLRETLVQDNIQWPTGLAVDYHNERLYWADAKLSVIGSIR 4073
Query: 2758 FDGKN-VVKLDIDNPI--PVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADE 2928
+G + +V D + P +I + +YIY V + ++HK G S +V G
Sbjct: 4074 LNGTDPIVAADSKRGLSHPFSIDVFEDYIYGVTYINNRVFKIHK--FGHSPLVNLTGGLS 4131
Query: 2929 RSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINK 3108
+ + H+ + +PC +C LC +PS C C G +
Sbjct: 4132 HASDVVLYHQHKQPEV-----TNPCDRKKCEWLCLLSPS-------GPVCTCPNG---KR 4176
Query: 3109 ENNHSCQKDPAEKIEQLCSSNST-QFQCKN-GRCI---PKEWKCDGENDCLDESDEIDEK 3273
+N +C P+ T QC N G C ++ KC + + E+D+
Sbjct: 4177 LDNGTCVPVPSPTPPPDAPRPGTCNLQCFNGGSCFLNARRQPKCRCQPRYTGDKCELDQC 4236
Query: 3274 GDKCFHETECA 3306
+ C + CA
Sbjct: 4237 WEHCRNGGTCA 4247
Score = 63.9 bits (154), Expect = 1e-07
Identities = 53/172 (30%), Positives = 70/172 (39%), Gaps = 18/172 (10%)
Frame = +1
Query: 8596 LDCPSAVACAEGTFPCSNG-HCINQTKVCDGHNDCHDEQVSDESLATCPGLPID-CRGVK 8769
+D P C+ F C + CI++ CDG DC D SDE+ CP C+ +
Sbjct: 21 IDAPKT--CSPKQFACRDQITCISKGWRCDGERDCPDG--SDEAPEICPQSKAQRCQPNE 76
Query: 8770 VRCPNTNICIQPADLCDGYDDCGDKADEN------QLFCMNQQCAQHYVRCPSGRC--IP 8925
C T +C+ + LC+G DC D +DE Q C C H V G
Sbjct: 77 HNCLGTELCVPMSRLCNGVQDCMDGSDEGPHCRELQGNCSRLGCQHHCVPTLDGPTCYCN 136
Query: 8926 ETWQCDGDNDCSDGWDETHTN------CTDTAGKKI--CVGDYLFQCDNLKC 9057
++Q D +DE CT+T G I CV YL Q DN C
Sbjct: 137 SSFQLQADGKTCKDFDECSVYGTCSQLCTNTDGSFICGCVEGYLLQPDNRSC 188
Score = 62.8 bits (151), Expect = 2e-07
Identities = 113/491 (23%), Positives = 169/491 (34%), Gaps = 25/491 (5%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDEKD--CPASTVDCSSQNVFMCADG 447
C Q+ C ++CI++ RCD DC DGSDE CP S N C
Sbjct: 27 CSPKQFACRD----QITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGT 82
Query: 448 RQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCA 627
C +S+ C+G DC D SDE C C + C C
Sbjct: 83 ELCVPMSRLCNGVQDCMDGSDEGPHCRELQGNC--------SRLGC---------QHHCV 125
Query: 628 DGSDEPDTCEFKKCTAN-EFQCKNKRCQPRKFRCDYYDDCGD---NSDED-ECG---EYR 783
D P TC C ++ + Q K C+ C Y C N+D CG Y
Sbjct: 126 PTLDGP-TC---YCNSSFQLQADGKTCKDFD-ECSVYGTCSQLCTNTDGSFICGCVEGYL 180
Query: 784 CPPGKWNCPGTGHCIDQ---LKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGG 954
P +C +D+ L + + A Q S + P+ Q +
Sbjct: 181 LQPDNRSCKAKNEPVDRPPVLLIANSQNILATYLSGAQVS-TITPTSTRQTTAMDFSYAN 239
Query: 955 ECTCPSGYKLDDRFHRTCSDINECAEF----GYCDQLCANHRPGFTCSCLGDCFTLQMEH 1122
E C + D +T +CA G+ D+ N +L + H
Sbjct: 240 ETVC--WVHVGDSAAQTQL---KCARMPGLKGFVDEHTIN-------------ISLSLHH 281
Query: 1123 --GPGKDNLTMRGYCVSNNADKMKLFVARREG-----LYRLNPKNPDEEVKKLASGEFIY 1281
D LT Y V + D ++FV R G L L NP
Sbjct: 282 VEQMAIDWLTGNFYFVDDIDD--RIFVCNRNGDTCVTLLDLELYNPK------------- 326
Query: 1282 GIDFDYGDRKIFWTD-RLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLY 1458
GI D K+F+TD D+D + KL +V+P + +D ++ +Y
Sbjct: 327 GIALDPAMGKVFFTDYGQIPKVERCDMDGQNR----TKLVDSKIVFPHGITLDLVSRLVY 382
Query: 1459 IIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTNQLKLEAAAMDGTNR 1638
++ I+V Y+G+ R ++ G+ + L ++ TN A R
Sbjct: 383 WADAYLDYIEVVDYEGKGRQTII-QGILIEHLYGLTVFENYLYATNSDNANAQQKTSVIR 441
Query: 1639 RTLVNTHTHQV 1671
N+ +QV
Sbjct: 442 VNRFNSTEYQV 452
Score = 60.1 bits (144), Expect = 2e-06
Identities = 31/82 (37%), Positives = 40/82 (47%), Gaps = 5/82 (6%)
Frame = +1
Query: 8365 AKECLPPYNFQCGDG-SCILLGATCDSKPDCADASDENPNYCNT----RSCPEDYNLCTN 8529
A + P F C D +CI G CD + DC D SDE P C R P ++N
Sbjct: 23 APKTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGT 82
Query: 8530 RRCIDSAKKCNHIDDCGDGSDE 8595
C+ ++ CN + DC DGSDE
Sbjct: 83 ELCVPMSRLCNGVQDCMDGSDE 104
Score = 53.5 bits (127), Expect = 1e-04
Identities = 33/66 (50%), Positives = 35/66 (53%), Gaps = 3/66 (4%)
Frame = +1
Query: 10861 KTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQ-C- 11034
KTC P +QFAC D CI K W CDGE DC DGSDE E ICP + Q C
Sbjct: 25 KTCSP----KQFACR-DQITCISKGWRCDGERDCPDGSDEAPE------ICPQSKAQRCQ 73
Query: 11035 -TNHNC 11049
HNC
Sbjct: 74 PNEHNC 79
Score = 52.0 bits (123), Expect = 4e-04
Identities = 51/202 (25%), Positives = 79/202 (38%), Gaps = 10/202 (4%)
Frame = +1
Query: 11239 MSAERNCTAEEFRCNNN-KCIAKAWRXXXXXXXXXXXXETPE-CAQIE---CKKGWTRCS 11403
+ A + C+ ++F C + CI+K WR E PE C Q + C+ C
Sbjct: 21 IDAPKTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCL 80
Query: 11404 SSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSG---KCIPRRWMCDTEN 11574
+ C+P CNG DC D SDE P C ++ + C+ G C+P
Sbjct: 81 GTELCVPMSRLCNGVQDCMDGSDEG----PHCREL-QGNCSRLGCQHHCVP--------- 126
Query: 11575 DCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCT-LRRC 11751
+ G T C+ S DGK C CS + + + C
Sbjct: 127 -----------TLDGPTCYCNSSFQLQADGKTCKDFDECSVYGTCSQLCTNTDGSFICGC 175
Query: 11752 LPGH-RQCDDGTCIAEHKWCDR 11814
+ G+ Q D+ +C A+++ DR
Sbjct: 176 VEGYLLQPDNRSCKAKNEPVDR 197
Score = 47.8 bits (112), Expect = 0.008
Identities = 55/222 (24%), Positives = 77/222 (33%), Gaps = 8/222 (3%)
Frame = +1
Query: 11743 RRCLPGHRQCDDG-TCIAEHKWCDRKKDCPNAADELH--CEDVSRRTCSPFEFEC-ANSV 11910
+ C P C D TCI++ CD ++DCP+ +DE C + C P E C +
Sbjct: 25 KTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTEL 84
Query: 11911 CIPRKFMXXXXXXXXXXSDETSSECRSAQ--CDPPLRFRCAHSRLCLNILQLCNGFNDCG 12084
C+P + SDE CR Q C R C H C+ L G
Sbjct: 85 CVPMSRLCNGVQDCMDGSDE-GPHCRELQGNCS---RLGCQHH--CVPTLD--------G 130
Query: 12085 PNDFSDEHLSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGG 12264
P + C+S A+GK C D+C
Sbjct: 131 PTCY----------------CNSSFQLQADGK------TCKDFDEC-------------- 154
Query: 12265 KTSCEAFGNNGGCKHICTDVRDGFYCHCRDGF--RPDPQSPK 12384
G C +CT+ F C C +G+ +PD +S K
Sbjct: 155 -------SVYGTCSQLCTNTDGSFICGCVEGYLLQPDNRSCK 189
Score = 42.0 bits (97), Expect = 0.44
Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 24/96 (25%)
Frame = +1
Query: 4210 DRAGCSFKCHNSPNGPICSCPFGEQLVNKTKCEP----------------ENECLDSSSC 4341
DR C + C SP+GP+C+CP G++L N T C P +C + SC
Sbjct: 4152 DRKKCEWLCLLSPSGPVCTCPNGKRLDNGT-CVPVPSPTPPPDAPRPGTCNLQCFNGGSC 4210
Query: 4342 --------SQRCKDEKHGFTCSCDEGYELDVDKRTC 4425
RC+ G C D+ +E + TC
Sbjct: 4211 FLNARRQPKCRCQPRYTGDKCELDQCWEHCRNGGTC 4246
Score = 41.2 bits (95), Expect = 0.75
Identities = 60/231 (25%), Positives = 85/231 (35%), Gaps = 29/231 (12%)
Frame = +1
Query: 9142 TCTDQEFH---CTSNAKLAQPKYECIPR----------AWL-CDGDVTCAGGEDESTELC 9279
TC Q F+ C NA+ QPK C PR W C TCA C
Sbjct: 4199 TCNLQCFNGGSCFLNAR-RQPKCRCQPRYTGDKCELDQCWEHCRNGGTCAASPS-GMPTC 4256
Query: 9280 KTEKKECNKGEF--RCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFF--QCAN 9447
+ C G +C+ Q C C ++ C C C P F +C
Sbjct: 4257 R-----CPTGFTGPKCTQQVC---AGYCANNSTCTVNQGNQPQCR---CLPGFLGDRCQY 4305
Query: 9448 HKCVPNSWKCDGNDDCE---DGSDEKDCPKN-SASAQKASKCSNGQFQCTSGECIDDAKV 9615
+C S C+ C+ DGS + C S + +KCS +C G C+ + +
Sbjct: 4306 RQC---SGYCENFGTCQMAADGSRQCRCTAYFEGSRCEVNKCS----RCLEGACVVNKQS 4358
Query: 9616 CDRNFDCTD-RSDESSLCFIDECS------LAEKPLCEQKCMDMKIGYKCD 9747
D +CTD R S L + CS + K + E +C G +C+
Sbjct: 4359 GDVTCNCTDGRVAPSCLTCVGHCSNGGSCTMNSKMMPECQCPPHMTGPRCE 4409
>gi|15825005|gb|AAL09566.1| lipoprotein receptor-related protein [Mus
musculus]
Length = 4545
Score = 2029 bits (5257), Expect = 0.0
Identities = 1389/4508 (30%), Positives = 2101/4508 (45%), Gaps = 174/4508 (3%)
Frame = +1
Query: 661 KKCTANEFQCKNK-RCQPRKFRCDYYDDCGDNSDE-----DECGEYRCPPGKWNCPGTGH 822
K C+ +F C+++ C + +RCD DC D SDE + RCPP + +C GT
Sbjct: 26 KTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEHSCLGTEL 85
Query: 823 CIDQLKLCDGSKDCADGADEQQCSQNL---CPSLGCQAGCHPSPHGGECTCPSGYKLDDR 993
C+ +LC+G +DC DG+DE + L C +GCQ C P+P G C C S ++L
Sbjct: 86 CVPMSRLCNGIQDCMDGSDEGAHCRELRANCSRMGCQHHCVPTPSGPTCYCNSSFQLQAD 145
Query: 994 FHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNN 1173
+TC D +EC+ +G C QLC N FTC C+ + + LQ DN + C + N
Sbjct: 146 -GKTCKDFDECSVYGTCSQLCTNTDGSFTCGCV-EGYLLQ------PDNRS----CKAKN 193
Query: 1174 ADKMK---LFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSA 1344
+ L +A + + S +DF Y + + W + SA
Sbjct: 194 EPVDRPPVLLIANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWV-HVGDSA 252
Query: 1345 FSADVD-----------DEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDV 1491
+ DE I+ +SL SL + +A+DW+T Y ++ RI V
Sbjct: 253 AQTQLKCARMPGLKGFVDEHTIN----ISL-SLHHVEQMAIDWLTGNFYFVDDIDDRIFV 307
Query: 1492 SSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTNQ---LKLEAAAMDGTNRRTLVNTHT 1662
+ +G+ LL L P IALDP G++FFT+ K+E MDG NR LV++
Sbjct: 308 CNRNGDTCVTLLDLELYNPKGIALDPAMGKVFFTDYGQIPKVERCDMDGQNRTKLVDSKI 367
Query: 1663 HQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYW 1842
GI +D+ ++ VYW D +D +E +DY+G R+ + QG+ ++ H +GL +F+ YLY
Sbjct: 368 VFPHGITLDLVSRLVYWADAYLDYIEVVDYEGKGRQTIIQGI-LIEHLYGLTVFENYLYA 426
Query: 1843 TD------WTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMK 2004
T+ + VI+V +F S + + + + YH QP C +
Sbjct: 427 TNSDNANTQQKTSVIRVNRFNSTEYQVVTRVDKGG---ALHIYHQRRQPRVRSHACENDQ 483
Query: 2005 IENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKL-VNGKRCIDSIDYLLFSSNK--- 2172
P C +C+L+ + C C G L +GK C L K
Sbjct: 484 YGKP---GGCSDICLLANSHKA----RTCRCRSGFSLGSDGKSCKKPEHELFLVYGKGRP 536
Query: 2173 -IVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFF--YADIMDNTIYRI 2343
I+RG+ ++ K E ++PI + R D H + F +AD I R
Sbjct: 537 GIIRGM--DMGAKVPDEHMIPIENLMNPRA-------LDFHAETGFIYFADTTSYLIGRQ 587
Query: 2344 RPDGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDN-IRNSLEVVKIGETGLVHPDELVRR 2520
+ DG +L + ++ DW+ LY+ D+ + ++ V ++ + R+
Sbjct: 588 KIDGTERETILKDGIHNVEGVAVDWMGDNLYWTDDGPKKTISVARLEKAAQT------RK 641
Query: 2521 QLIT-ELRDPVSVVVHPWKGLLFYAE------AMRPAAIYRCHIDGQNCQV-IRNTTLGR 2676
LI ++ P ++VV P G +++ + R + R +DG + + + + T+
Sbjct: 642 TLIEGKMTHPRAIVVDPLNGWMYWTDWEEDPKDSRRGRLERAWMDGSHRDIFVTSKTVLW 701
Query: 2677 PSEMAIDFAENRLCWGDTLLKTISCMDFDG--KNVVKLDIDNPIPVAITIMNEYIYYVHQ 2850
P+ +++D RL W D I + +G + +V + + Y+++
Sbjct: 702 PNGLSLDIPAGRLYWVDAFYDRIETILLNGTDRKIVYEGPELNHAFGLCHHGNYLFWTEY 761
Query: 2851 RPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQ--CTQ 3024
R S+ R+ + G V ++ IF ++ Q Q + + CR + C+
Sbjct: 762 RSGSVYRLERGVAGAPPTVTLLRSERPPIFEIRMYDAQQQQVGTNK----CRVNNGGCSS 817
Query: 3025 LCFATPSESHPNELEAKCACRQGFMINKENNHSCQKDPAEKIEQLCSSNSTQFQCKNGRC 3204
LC ATP +CAC + +++ + +C +P+ C +F C N RC
Sbjct: 818 LCLATPGSR-------QCACAEDQVLDTDGV-TCLANPSYVPPPQCQPG--EFACANNRC 867
Query: 3205 IPKEWKCDGENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKKCIPAQXXXXXXXXXX 3384
I + WKCDG+NDCLD SDE C ++T
Sbjct: 868 IQERWKCDGDNDCLDNSDEAPAL---------CHQHT----------------------- 895
Query: 3385 XXXXXXVKYCKDGQKPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNATCA 3564
C + +F+C+N+RCIP +W E C TC
Sbjct: 896 -----------------CPSDRFKCENNRCIPNRWLCDGDNDCGNSEDESNATCSARTCP 938
Query: 3565 ANQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQCVPLRNHX 3744
NQFSCA+GRCIPI W CD D+DC D +DE P QF C NGR C+ N
Sbjct: 939 PNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNGR-CI---NIN 994
Query: 3745 XXXXXXXXXXXXXXXAVTAESCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCT 3924
A + SC+ QFKC +SG CIP W SDE CT
Sbjct: 995 WRCDNDNDCGDNSDEAGCSHSCSSTQFKC-NSGRCIPEHWTCDGDNDCGDYSDETHANCT 1053
Query: 3925 SGRQ-----CSSDQFKCG-NGRCILNNWLCDGENDCGDGSDESS------------ERGC 4050
+ C SD+F+C +G CI W CDG+ DC D SDE S + GC
Sbjct: 1054 NQATRPPGGCHSDEFQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPNVKFGC 1113
Query: 4051 KTSMN------------------------ARKCPFEHVACENDQETCIPLHQLCDGKTHC 4158
K S A C C N+ C+P +LCDGK C
Sbjct: 1114 KDSARCISKAWVCDGDSDCEDNSDEENCEALACRPPSHPCANNTSVCLPPDKLCDGKDDC 1173
Query: 4159 PGGTDEGGRCARDLCSADRAGCSFKCHNSPN-GPICSCPFGEQLVNKTK-CEPENECLDS 4332
G+DEG C D CS + GCS C +P G +CSCP G +L + C+ ++ C
Sbjct: 1174 GDGSDEGELC--DQCSLNNGGCSHNCSVAPGEGIVCSCPLGMELGSDNHTCQIQSYCAKH 1231
Query: 4333 SSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNW 4512
CSQ+C K CSC EG+ L+ D +C+ D K I+ SNR+ I D ++
Sbjct: 1232 LKCSQKCDQNKFSVKCSCYEGWVLEPDGESCRSLDPFKPFIIF-SNRHEIRRIDLHKGDY 1290
Query: 4513 HTFGAIVENAIALAWDSLTDRIYWSDIREKKI----LSANRNGTNATVFIADGLDITEGI 4680
+ N IAL + +YW+D+ E KI L N T+ V I GL EG+
Sbjct: 1291 SVLVPGLRNTIALDFHLSQSALYWTDVVEDKIYRGKLLDNGALTSFEVVIQYGLATPEGL 1350
Query: 4681 ALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQ 4860
A+DW+ N+YWV+S+L+ IEVA L D RT L+ ++ PR IA+DPR G++FWTDW
Sbjct: 1351 AVDWIAGNIYWVESNLDQIEVAKL-DGTLRTTLLAGDIEHPRAIALDPRDGILFWTDWDA 1409
Query: 4861 N-PCIERASMDGTDRQIIVKTKIY--WPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGR 5031
+ P IE ASM G R+ I + WPN + +DY R+ + D++ D I YDGSG
Sbjct: 1410 SLPRIEAASMSGAGRRTIHRETGSGGWPNGLTVDYLEKRILWIDARSDAIYSARYDGSGH 1469
Query: 5032 TQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVA 5211
+VL +F+ HP A+ ++ +Y++D R L K+ G T ++ +
Sbjct: 1470 MEVLRGHEFLSHPFAVTLYGGEVYWTDWRTNTLAKANKW-TGHNVTVVQRTNTQPFDLQV 1528
Query: 5212 VHPVLQPVIKNNPCSTN----PCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKPFL 5379
HP QP+ N PC N PCSHLCL+N T +C CP KL C + K FL
Sbjct: 1529 YHPSRQPMAPN-PCEANGGRGPCSHLCLINYNRTVSCACPHLMKLHKDNTTCYE-FKKFL 1586
Query: 5380 VIIQKTNVFGIEMNSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTL 5559
+ ++ + G+++++ +++ VP + N YDA + ++ +
Sbjct: 1587 LYARQMEIRGVDLDAPYYNY--IISFTVP--DIDNVTVLDYDAREQRVYWSD-------- 1634
Query: 5560 AQITTDSAIYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKIT--QTIEIIRT 5733
AI R+ +NG + S+ +P+ A+ L DW RNL + T + I + R
Sbjct: 1635 ---VRTQAIKRAFINGTGVETVVSADLPN-AHGLAVDWVSRNLFWTSYDTNKKQINVARL 1690
Query: 5734 QGKQYRSVILSNDQSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLV 5913
G +V+ +Q +G ++W D ++ A +DGSN +
Sbjct: 1691 DGSFKNAVVQGLEQPHGLVVHPL-------RGKLYWTDGDN------ISMANMDGSNHTL 1737
Query: 5914 IASNDLAELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGR--QPNGLAFY 6087
+ S + +AID +++Y+ + I+ DG + + + + + LA
Sbjct: 1738 LFSGQKGPVG-LAIDFPESKLYWISSGNHTINRCNLDGSELEVIDTMRSQLGKATALAIM 1796
Query: 6088 GDRLFYADSAFDSIEVATINGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHINNG 6267
GD+L++AD + + S + V ++ +PC +NNG
Sbjct: 1797 GDKLWWADQVSEKMGTCNKADGSGSVVLRNSTTLVMHMKVYDESIQLEHEGTNPCSVNNG 1856
Query: 6268 NCDHICIPLMFAQRTCTCANGY-VKDGQTSCKLFDESFVIVATKTKVIGYPIDETQSKGV 6444
+C +C+P R+C C GY ++ GQ +C+ SF++ + + G P+D K
Sbjct: 1857 DCSQLCLPTSETTRSCMCTAGYSLRSGQQACEGVG-SFLLYSVHEGIRGIPLDPND-KSD 1914
Query: 6445 AMEPIGGLSIT-GVDYDYESKTIYVAEA--SGINKGITAYTIGESSPRAVIRDSIGSLTI 6615
A+ P+ G S+ G+D+ E+ TIY + S I++ T E V+ + IG +
Sbjct: 1915 ALVPVSGTSLAVGIDFHAENDTIYWVDMGLSTISRAKRDQTWRED----VVTNGIGR--V 1968
Query: 6616 KSLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWA 6795
+ +A+DWI N+Y+ + + IEV++L+G++R ++++ + P +I V P YL+W
Sbjct: 1969 EGIAVDWIAGNIYWTDQGFDV--IEVARLNGSFRYVVISQGLDKPRAITVHPEKGYLFWT 2026
Query: 6796 DQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVR-STGG 6972
+ G P I+RS LDG+ R V+V+ I+ P + VD +YW DA+MD I R+ TG
Sbjct: 2027 EWGHYPRIERSRLDGTERVVLVNVSISWPNGISVDYQGGKLYWCDARMDKIERIDLETGE 2086
Query: 6973 TPELV-RSDIASAAGVALHGQNMYWTDN-RLEKLFRATSKPNQTSLLLSPTTVAASLKDI 7146
E+V S+ V++ +YW+D + K N T + T + LKDI
Sbjct: 2087 NREVVLSSNNMDMFSVSVFEDFIYWSDRTHANGSIKRGCKDNATDSVPLRTGIGVQLKDI 2146
Query: 7147 GDVAVFSSNNQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCARGVLK--GRTCEE 7320
VF+ + Q + ++ C + + C QLC G Q C+CA G+L G +C E
Sbjct: 2147 ---KVFNRDRQ-KGTNVCAVANG----GCQQLCLYRGGGQR-ACACAHGMLAEDGASCRE 2197
Query: 7321 PDTYIMFSDGDKIIDVAIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGV 7500
Y+++S+ + + + + + P++ PF + +++ + L Y SP
Sbjct: 2198 YAGYLLYSERTILKSIHLSDERNLNAPVQ-PFEDPEHMKNV---IALAFDYRAGTSPGTP 2253
Query: 7501 NISWFSMNNAENPRLVF--GASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVM--AI 7668
N +FS + N + + G+ + + + + + +Y+T+ + +
Sbjct: 2254 NRIFFSDIHFGNIQQINDDGSGRTTIVENVGSVEGLAYHRGWDTLYWTSYTTSTITRHTV 2313
Query: 7669 DTAG------EHLSTIASGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGG 7830
D E + T++ D A +D C L+FW T+ P I R+ L+G
Sbjct: 2314 DQTRPGAFERETVITMSGDDHPRAFVLDECQNLMFW------TNWNELHPSIMRAALSGA 2367
Query: 7831 SRKVIVSESISLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGYRAK--SLD 8004
+ ++ + I P +A+D R +K+Y++D IE +YDG +R VI L
Sbjct: 2368 NVLTLIEKDIRTPNGLAIDHRAEKLYFSDATLDKIERCEYDGSHRYVILKSEPVHPFGLA 2427
Query: 8005 IWDRWLYMSDPLSNGVFRIDKESGSGLENVVSDRRIPGA-LRVFASESDVRTRNQVCNAL 8181
++ ++ +D + V R +K GS ++ + D IP + + A +D N+
Sbjct: 2428 VYGEHIFWTDWVRRAVQRANKYVGSDMKLLRVD--IPQQPMGIIAVANDT-------NSC 2478
Query: 8182 TSQLCKTDNGGCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSE 8361
C+ +NGGC LC + V CSC G+ R NS
Sbjct: 2479 ELSPCRINNGGCQDLCLLTHQ------GHVNCSCRG--------GRILQEDFTCRAVNSS 2524
Query: 8362 PAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCI 8541
C F+C +G CI TCD C D SDE P+YCN+R C + + C N RC+
Sbjct: 2525 ----CRAQDEFECANGECISFSLTCDGVSHCKDKSDEKPSYCNSRRCKKTFRQCNNGRCV 2580
Query: 8542 DSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDE 8721
+ CN +DDCGDGSDE+ C + AC G F C +G CI + C+ DC D SDE
Sbjct: 2581 SNMLWCNGVDDCGDGSDEIPC-NKTACGVGEFRCRDGSCIGNSSRCNQFVDCED--ASDE 2637
Query: 8722 ---SLATCPG-LPIDCRGVKVR-CPNTNICIQPADLCDGYDDCGDKADENQLFCMNQ-QC 8883
S C + +GV + C T++C P+ +CDG +DCGD +DE + + +C
Sbjct: 2638 MNCSATDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDERDCPGVKRPRC 2697
Query: 8884 AQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCIS 9063
+Y CPSGRCIP +W CD ++DC +G DETH N K C + F+C N +CIS
Sbjct: 2698 PLNYFACPSGRCIPMSWTCDKEDDCENGEDETHCN-------KFC-SEAQFECQNHRCIS 2749
Query: 9064 RAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVT 9243
+ ++ + C +TC F C + C+P WLCDGD
Sbjct: 2750 KQWLCDGSDDCGDGSDEAAH--CEGKTCGPSSFSCPGT-------HVCVPERWLCDGDKD 2800
Query: 9244 CAGGEDESTELCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQ 9423
C G DES C+ EF C N+ CI + CD D DC DGSDE C Y +C
Sbjct: 2801 CTDGADESVTAGCLYNSTCDDREFMCQNRLCIPKHFVCDHDRDCADGSDESPECEYPTCG 2860
Query: 9424 PDFFQCANHKCVPN-SWKCDGNDDCEDGSDEKDCPKNSASAQKASKCS-NGQFQCTSGEC 9597
P+ F+CAN +C+ + W+CDG +DC D SDE PKN KC+ + QF C+SG C
Sbjct: 2861 PNEFRCANGRCLSSRQWECDGENDCHDHSDE--APKNPHCTSPEHKCNASSQFLCSSGRC 2918
Query: 9598 IDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDIS 9777
+ +A +C+ DC D SDE C ++EC + C Q C D+KIG+KC C GF +
Sbjct: 2919 VAEALLCNGQDDCGDGSDERG-CHVNECLSRKLSGCSQDCEDLKIGFKCRCRPGFRLK-D 2976
Query: 9778 DQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQ-LSSDDHSCKRTEMEPEPFFLL 9954
D ++C +++EC CSQ C + GSYKC CV+GY D HSCK E EPF +
Sbjct: 2977 DGRTCADLDECSTTFP-CSQLCINTHGSYKCLCVEGYAPRGGDPHSCKAVTDE-EPFLIF 3034
Query: 9955 ANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLID---QGKLRLLRVDLDEMD 10125
AN++Y+RK+++DG+ Y L QG +N V+LD D E+ Y D QG + + R+ L+
Sbjct: 3035 ANRYYLRKLNLDGSNYTLLKQGLNNAVALDFDYREQMIYWTDVTTQGSM-IRRMHLNG-- 3091
Query: 10126 SPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQP 10305
S+ + + R + +G+AVDWVG LY ++ +I V +L+G + L+ +++P
Sbjct: 3092 ---SNVQVLHRTGLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVSSGLREP 3148
Query: 10306 KAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDR 10485
+A+VV GYL++T+W IGRI +DGS + + + WPN + +DY ++R
Sbjct: 3149 RALVVDVQNGYLYWTDWGDHSLIGRIGMDGSGRSI-----IVDTKITWPNGLTVDYVTER 3203
Query: 10486 LFWGDAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTG 10665
++W DA + I F DG+ R + +Q H+ ++ +F+DY+YW DW + + R K TG
Sbjct: 3204 IYWADAREDYIEFASLDGSNRHVVLSQDIPHIFALTLFEDYVYWTDWETKSINRAHKTTG 3263
Query: 10666 KNETILKKTVQLPNDLRIVHPMRQPAYPN-PCGDNNGGCSHLCLIGAGGNGYTCSCPDQF 10842
N+T+L T+ P DL + H +RQP PN PC NNGGCS+LCL+ GG G+ C+CP F
Sbjct: 3264 ANKTLLISTLHRPMDLHVFHALRQPDVPNHPCKVNNGGCSNLCLLSPGG-GHKCACPTNF 3322
Query: 10843 VLLSDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVG 11022
L D +TC NCT QF C D KCIP W CD E DC D SDEP + C + C G
Sbjct: 3323 YLGGDGRTCVSNCTASQFVCKND--KCIPFWWKCDTEDDCGDHSDEPPD--CPEFKCRPG 3378
Query: 11023 EFQCTNHNCTRPFQIXXXXXXXXXXXXEQNCD-KACDPWMFKCAATGRCIPRRFTXXXXX 11199
+FQC+ CT P I E NCD C P FKC T RCIP F
Sbjct: 3379 QFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQD 3438
Query: 11200 XXXXRSDEADTLCMSAERNCTAEEFRCN-NNKCIAKAWRXXXXXXXXXXXXETPECAQIE 11376
DE D E C +F+C+ +CI + W E C Q+
Sbjct: 3439 NCGDGEDERD----CPEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQMT 3494
Query: 11377 CKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCP--TCDDVGEFRCATSGKCIPR 11550
C RC S RCIP C+G+DDC D SDE K+ C TC+ +FRC + +C+P
Sbjct: 3495 CGVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPY-QFRC-KNNRCVPG 3552
Query: 11551 RWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDES 11730
RW CD +NDCGDNSDE SC T RPCSESEF C +G+CI G CDG C+DG DE
Sbjct: 3553 RWQCDYDNDCGDNSDE--ESC--TPRPCSESEFSCANGRCIAGRWKCDGDHDCADGSDEK 3608
Query: 11731 QCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFECANSV 11910
CT RC QC G CI CD DC + +DE C RTC EF+C N++
Sbjct: 3609 DCT-PRCDMDQFQCKSGHCIPLRWRCDADADCMDGSDEEAC-GTGVRTCPLDEFQCNNTL 3666
Query: 11911 CIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPN 12090
C P + SDE EC C P FRC + R+CL I + C+G ++CG
Sbjct: 3667 CKPLAWKCDGEDDCGDNSDENPEECARFICPPNRPFRCKNDRVCLWIGRQCDGVDNCG-- 3724
Query: 12091 DFSDEHLSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKT 12270
D +DE + +F C N +C++ ++ C+ DDCGD SDE CS T
Sbjct: 3725 DGTDEEDCEPPTAQNPHCKDKKEFLCRNQRCLSSSLRCNMFDDCGDGSDEEDCSIDPKLT 3784
Query: 12271 SCEAFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTK 12450
SC + G + C YC CR GF P P C DI+EC TC+QLC NTK
Sbjct: 3785 SCATNASMCGDEARCVRTEKAAYCACRSGFHTVPGQP-GCQDINECLRFGTCSQLCNNTK 3843
Query: 12451 GSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGSGTNRHXXXXX 12630
G +LC C ++ T C+A+G V+ ADD+ ++ G + +
Sbjct: 3844 GGHLCSCARNF-------MKTHNTCKAEGSEYQVLYIADDNEIRSLFPGHPHSAYEQTFQ 3896
Query: 12631 XXXXXXXXXXXXXPRKELMYWIDGSERTI-YRS---AIANGNQSHEGQKLDVDFAAMGV- 12795
+ +YW + TI YRS A + +++D + +
Sbjct: 3897 GDESVRIDAMDVHVKAGRVYWTNWHTGTISYRSLPPAAPPTTSNRHRRQIDRGVTHLNIS 3956
Query: 12796 ---VPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYL 12966
+P IA+D+ GN++ ++ I V G
Sbjct: 3957 GLKMPRGIAIDWVAGNVYWTDSGRDV-----------------------IEVAQMKGENR 3993
Query: 12967 KKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAI 13146
K +++G + +P A++ P G + +SD G H KIE A MDGT R+ +V+D + PT +A+
Sbjct: 3994 KTLISGMIDEPHAIVVDPLRGTMYWSDWGNHPKIETAAMDGTLRETLVQDNIQWPTGLAV 4053
Query: 13147 DEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRH---IPYAVDVFENHIYWLSRESKT 13317
D R+YW D K + ++ ++G++ + P+++DVFE++IY ++ +
Sbjct: 4054 DY-HNERLYWADAKLSVIGSIRLNGTDPIVAADSKRGLSHPFSIDVFEDYIYGVTYINNR 4112
Query: 13318 LYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTGFA 13497
++ KFG + L L H V + + C+R +C LC+ PS G
Sbjct: 4113 VFKIHKFGHSPLINLTGGL--SHASDVVLYHQHKQPEVTNPCDRKKCEWLCLLSPS-GPV 4169
Query: 13498 CLCPDGIVPQLD-GSCATQHVEALTMPKQC--------KCTNGGKCRLDG----SCECTS 13638
C CP+G +LD G+C V + T P +C NGG C L+ C C
Sbjct: 4170 CTCPNG--KRLDNGTCVP--VPSPTPPPDAPRPGTCTLQCFNGGSCFLNARRQPKCRCQP 4225
Query: 13639 DFEGDQCE 13662
+ GD+CE
Sbjct: 4226 RYTGDKCE 4233
Score = 360 bits (925), Expect = 4e-97
Identities = 283/1025 (27%), Positives = 442/1025 (42%), Gaps = 25/1025 (2%)
Frame = +1
Query: 130 ASVNTASSVCNENDFRCNDGKCIRTEWX-XXXXXXXXXXXXXXXXPHPGCKSDQWQCDTY 306
++ ++ C N F C G+CI W +P C + +
Sbjct: 928 SNATCSARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPTC----FPLTQF 983
Query: 307 TWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGK 486
T ++ CI RCDN DC D SDE C S CSS F C GR C CDG
Sbjct: 984 TCNNGRCININWRCDNDNDCGDNSDEAGCSHS---CSSTQ-FKCNSGR-CIPEHWTCDGD 1038
Query: 487 YDCRDLSDEKD-SCSRNHT----ACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDT 651
DC D SDE +C+ T C +F+C CI W CDG DC D SDE +
Sbjct: 1039 NDCGDYSDETHANCTNQATRPPGGCHSDEFQCRLDGLCIPLRWRCDGDTDCMDSSDE-KS 1097
Query: 652 CE--FKKCTAN-EFQCKNK-RCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCP-GT 816
CE C N +F CK+ RC + + CD DC DNSDE+ C C P C T
Sbjct: 1098 CEGVTHVCDPNVKFGCKDSARCISKAWVCDGDSDCEDNSDEENCEALACRPPSHPCANNT 1157
Query: 817 GHCIDQLKLCDGSKDCADGADE-QQCSQNLCPSLGCQAGCHPSP-HGGECTCPSGYKLDD 990
C+ KLCDG DC DG+DE + C Q + GC C +P G C+CP G +L
Sbjct: 1158 SVCLPPDKLCDGKDDCGDGSDEGELCDQCSLNNGGCSHNCSVAPGEGIVCSCPLGMELGS 1217
Query: 991 RFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSN 1170
H TC + CA+ C Q C ++ CSC + + L+ + G+ C S
Sbjct: 1218 DNH-TCQIQSYCAKHLKCSQKCDQNKFSVKCSCY-EGWVLEPD---GES-------CRSL 1265
Query: 1171 NADKMKLFVARREGLYRLNPKNPDEEVKKLASG-EFIYGIDFDYGDRKIFWTDRLAHSAF 1347
+ K + + R + R++ D V L G +DF ++WTD + +
Sbjct: 1266 DPFKPFIIFSNRHEIRRIDLHKGDYSV--LVPGLRNTIALDFHLSQSALYWTDVVEDKIY 1323
Query: 1348 SADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLL 1527
+ D G ++ + + L P LAVDWI +Y +ES +I+V+ DG RT LL
Sbjct: 1324 RGKLLDNGALTSFEVVIQYGLATPEGLAVDWIAGNIYWVESNLDQIEVAKLDGTLRTTLL 1383
Query: 1528 ADGLTLPLDIALDPLRGEMFFT----NQLKLEAAAMDGTNRRTLVNTHTHQ---VSGIVV 1686
A + P IALDP G +F+T + ++EAA+M G RRT ++ T +G+ V
Sbjct: 1384 AGDIEHPRAIALDPRDGILFWTDWDASLPRIEAASMSGAGRRT-IHRETGSGGWPNGLTV 1442
Query: 1687 DITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGV 1866
D KR+ W+D + D + S Y G+ V +G + HPF + L+ +YWTDW +
Sbjct: 1443 DYLEKRILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYGGEVYWTDWRTNTL 1502
Query: 1867 IQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMC 2046
+ K+ + T N P + YHP QP + C A PC++ +C
Sbjct: 1503 AKANKWTGHNVTVVQRT--NTQPFDLQVYHPSRQP-MAPNPCEANGGRGPCSH-----LC 1554
Query: 2047 ILSKDNGGFGVGYKCACPIGQKL-VNGKRCIDSIDYLLFSSNKIVRGIFPEINEKALAEA 2223
+++ + CACP KL + C + +LL++ +RG+ + A
Sbjct: 1555 LIN-----YNRTVSCACPHLMKLHKDNTTCYEFKKFLLYARQMEIRGVDLD------APY 1603
Query: 2224 VLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFS 2403
I + I ++ D +++D+ I R +G G V+
Sbjct: 1604 YNYIISFTVPDIDNVTVLDYDAREQRVYWSDVRTQAIKRAFINGTGVETVVSADLPNAHG 1663
Query: 2404 MSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKGLL 2583
++ DW+S+ L++ N ++ + D + ++ L P +VVHP +G L
Sbjct: 1664 LAVDWVSRNLFWTSYDTNKKQI------NVARLDGSFKNAVVQGLEQPHGLVVHPLRGKL 1717
Query: 2584 FYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFD 2763
++ + I ++DG N ++ + G P +AIDF E++L W + TI+ + D
Sbjct: 1718 YWTDGDN---ISMANMDGSNHTLLFSGQKG-PVGLAIDFPESKLYWISSGNHTINRCNLD 1773
Query: 2764 GKNVVKLDIDNP---IPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERS 2934
G + +D A+ IM + +++ Q + +K +G GS ++R
Sbjct: 1774 GSELEVIDTMRSQLGKATALAIMGDKLWWADQVSEKMGTCNKADGSGSVVLRN---STTL 1830
Query: 2935 IFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINKEN 3114
+ +K Q + + C+QLC T +E C C G+ + +
Sbjct: 1831 VMHMKVYDESIQLEHEGTNPCSVNNGDCSQLCLPT------SETTRSCMCTAGYSL-RSG 1883
Query: 3115 NHSCQ 3129
+C+
Sbjct: 1884 QQACE 1888
Score = 327 bits (839), Expect = 4e-87
Identities = 216/683 (31%), Positives = 311/683 (44%), Gaps = 21/683 (3%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAE 336
C N F C G+CI W + C Q++C + CI++
Sbjct: 2697 CPLNYFACPSGRCIPMSWTCDKEDDCENGEDETHC-NKFCSEAQFECQNHR-----CISK 2750
Query: 337 YQRCDNITDCADGSDEK-DCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDE 513
CD DC DGSDE C T SS F C C CDG DC D +DE
Sbjct: 2751 QWLCDGSDDCGDGSDEAAHCEGKTCGPSS---FSCPGTHVCVPERWLCDGDKDCTDGADE 2807
Query: 514 KDS--CSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQ 687
+ C N T C +F C ++ CI K +VCD +DCADGSDE CE+ C NEF+
Sbjct: 2808 SVTAGCLYNST-CDDREFMCQNRL-CIPKHFVCDHDRDCADGSDESPECEYPTCGPNEFR 2865
Query: 688 CKNKRC-QPRKFRCDYYDDCGDNSDE----DEC--GEYRCPPGKWNCPGTGHCIDQLKLC 846
C N RC R++ CD +DC D+SDE C E++C +G C+ + LC
Sbjct: 2866 CANGRCLSSRQWECDGENDCHDHSDEAPKNPHCTSPEHKCNASSQFLCSSGRCVAEALLC 2925
Query: 847 DGSKDCADGADEQQCSQNLCPS---LGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDI 1017
+G DC DG+DE+ C N C S GC C G +C C G++L D RTC+D+
Sbjct: 2926 NGQDDCGDGSDERGCHVNECLSRKLSGCSQDCEDLKIGFKCRCRPGFRLKDD-GRTCADL 2984
Query: 1018 NECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRG----YCVSNNADKM 1185
+EC+ C QLC N + C C+ + RG C + ++
Sbjct: 2985 DECSTTFPCSQLCINTHGSYKCLCV--------------EGYAPRGGDPHSCKAVTDEEP 3030
Query: 1186 KLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDD 1365
L A R L +LN + + K + +DFDY ++ I+WTD + +
Sbjct: 3031 FLIFANRYYLRKLNLDGSNYTLLKQGLNNAV-ALDFDYREQMIYWTDVTTQGSMIRRMHL 3089
Query: 1366 EGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTL 1545
G S ++ L L P LAVDW+ LY + G I+VS +G RTVL++ GL
Sbjct: 3090 NG--SNVQVLHRTGLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVSSGLRE 3147
Query: 1546 PLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWV 1716
P + +D G +++T + + MDG+ R +V+T +G+ VD +R+YW
Sbjct: 3148 PRALVVDVQNGYLYWTDWGDHSLIGRIGMDGSGRSIIVDTKITWPNGLTVDYVTERIYWA 3207
Query: 1717 DPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFGSDT 1896
D + D +E G++R +V +PH F L LF+ Y+YWTDW + + K
Sbjct: 3208 DAREDYIEFASLDGSNRHVVLS--QDIPHIFALTLFEDYVYWTDWETKSINRAHKTTGAN 3265
Query: 1897 KLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFG 2076
K L +T + PM + +H + QP C N C +C+LS G
Sbjct: 3266 KTLLISTLHR--PMDLHVFHALRQPDVPNHPC-------KVNNGGCSNLCLLSP-----G 3311
Query: 2077 VGYKCACPIGQKL-VNGKRCIDS 2142
G+KCACP L +G+ C+ +
Sbjct: 3312 GGHKCACPTNFYLGGDGRTCVSN 3334
Score = 315 bits (808), Expect = 2e-83
Identities = 222/745 (29%), Positives = 322/745 (42%), Gaps = 83/745 (11%)
Frame = +1
Query: 139 NTASSVCNENDFRCND-GKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWH 315
N C ++FRC D G+CI W P + D+ C+ Y +
Sbjct: 3489 NCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDGSD-----EPKEECDERTCEPYQFR 3543
Query: 316 SVS--CIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKY 489
+ C+ +CD DC D SDE+ C T S++ F CA+GR C KCDG +
Sbjct: 3544 CKNNRCVPGRWQCDYDNDCGDNSDEESC---TPRPCSESEFSCANGR-CIAGRWKCDGDH 3599
Query: 490 DCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTC--EFK 663
DC D SDEKD R C QF+C CI W CD DC DGSDE + C +
Sbjct: 3600 DCADGSDEKDCTPR----CDMDQFQC-KSGHCIPLRWRCDADADCMDGSDE-EACGTGVR 3653
Query: 664 KCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDE--DECGEYRCPPGK-WNCPGTGHCIDQ 834
C +EFQC N C+P ++CD DDCGDNSDE +EC + CPP + + C C+
Sbjct: 3654 TCPLDEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEECARFICPPNRPFRCKNDRVCLWI 3713
Query: 835 LKLCDGSKDCADGADEQQC----SQN---------LCPSLGC------------------ 921
+ CDG +C DG DE+ C +QN LC + C
Sbjct: 3714 GRQCDGVDNCGDGTDEEDCEPPTAQNPHCKDKKEFLCRNQRCLSSSLRCNMFDDCGDGSD 3773
Query: 922 ----------------------QAGCHPSPHGGECTCPSGYKLDDRFHRT-----CSDIN 1020
+A C + C C SG FH C DIN
Sbjct: 3774 EEDCSIDPKLTSCATNASMCGDEARCVRTEKAAYCACRSG------FHTVPGQPGCQDIN 3827
Query: 1021 ECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVA 1200
EC FG C QLC N + G CSC ++ + C + ++ L++A
Sbjct: 3828 ECLRFGTCSQLCNNTKGGHLCSC-------------ARNFMKTHNTCKAEGSEYQVLYIA 3874
Query: 1201 RREGLYRLNPKNPDEEVKKLASGE---FIYGIDFDYGDRKIFWTD----RLAHSAF---S 1350
+ L P +P ++ G+ I +D +++WT+ +++ + +
Sbjct: 3875 DDNEIRSLFPGHPHSAYEQTFQGDESVRIDAMDVHVKAGRVYWTNWHTGTISYRSLPPAA 3934
Query: 1351 ADVDDEGEISQIKK----LSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRT 1518
QI + L++ L PR +A+DW+ +Y +SG I+V+ GE R
Sbjct: 3935 PPTTSNRHRRQIDRGVTHLNISGLKMPRGIAIDWVAGNVYWTDSGRDVIEVAQMKGENRK 3994
Query: 1519 VLLADGLTLPLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVD 1689
L++ + P I +DPLRG M+++ N K+E AAMDGT R TLV + +G+ VD
Sbjct: 3995 TLISGMIDEPHAIVVDPLRGTMYWSDWGNHPKIETAAMDGTLRETLVQDNIQWPTGLAVD 4054
Query: 1690 ITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVI 1869
+R+YW D K+ + SI G D + A + HPF + +F+ Y+Y + V
Sbjct: 4055 YHNERLYWADAKLSVIGSIRLNGTDPIVAADSKRGLSHPFSIDVFEDYIYGVTYINNRVF 4114
Query: 1870 QVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCI 2049
++ KFG L + T + YH QP ++ NPC CE +C+
Sbjct: 4115 KIHKFGHSP--LINLTGGLSHASDVVLYHQHKQP----------EVTNPCDRKKCEWLCL 4162
Query: 2050 LSKDNGGFGVGYKCACPIGQKLVNG 2124
LS G C CP G++L NG
Sbjct: 4163 LSPS------GPVCTCPNGKRLDNG 4181
Score = 178 bits (451), Expect = 4e-42
Identities = 90/247 (36%), Positives = 125/247 (50%), Gaps = 1/247 (0%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAE 336
C F+C+ G C + C Q++C ++ CI
Sbjct: 3375 CRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCT----NTNRCIPG 3430
Query: 337 YQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEK 516
RC+ +C DG DE+DCP T + N F C+ ++C CD DC D SDE
Sbjct: 3431 IFRCNGQDNCGDGEDERDCPEVTC---APNQFQCSITKRCIPRVWVCDRDNDCVDGSDEP 3487
Query: 517 DSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEP-DTCEFKKCTANEFQCK 693
+C++ C +FRC D +CI W CDG DC DGSDEP + C+ + C +F+CK
Sbjct: 3488 ANCTQ--MTCGVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCK 3545
Query: 694 NKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADG 873
N RC P +++CDY +DCGDNSDE+ C C +++C G CI CDG DCADG
Sbjct: 3546 NNRCVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFSC-ANGRCIAGRWKCDGDHDCADG 3604
Query: 874 ADEQQCS 894
+DE+ C+
Sbjct: 3605 SDEKDCT 3611
Score = 143 bits (360), Expect = 1e-31
Identities = 89/293 (30%), Positives = 128/293 (43%), Gaps = 40/293 (13%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDE-KDCP----------ASTVDCSS 420
C + Q+ C + CI + +CD DC D SDE DCP ST C++
Sbjct: 3335 CTASQFVCK-----NDKCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQFQCSTGICTN 3389
Query: 421 --------------------------QNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDS 522
+ F C + +C +C+G+ +C D DE+D
Sbjct: 3390 PAFICDGDNDCQDNSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDC 3449
Query: 523 CSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNK- 699
C QF+C+ +CI + WVCD DC DGSDEP C C +EF+CK+
Sbjct: 3450 ---PEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDEFRCKDSG 3506
Query: 700 RCQPRKFRCDYYDDCGDNSDE--DECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADG 873
RC P +++CD DDCGD SDE +EC E C P ++ C C+ CD DC D
Sbjct: 3507 RCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCK-NNRCVPGRWQCDYDNDCGDN 3565
Query: 874 ADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAE 1032
+DE+ C+ C E +C +G + R+ C ++CA+
Sbjct: 3566 SDEESCTPRPCSE-------------SEFSCANGRCIAGRW--KCDGDHDCAD 3603
Score = 140 bits (354), Expect = 7e-31
Identities = 92/290 (31%), Positives = 123/290 (41%), Gaps = 45/290 (15%)
Frame = +1
Query: 148 SSVCNENDFRCNDGKCI--------------RTEWXXXXXXXXXXXXXXXXXPHPGCKSD 285
SS +++F C +G+CI +++ + C S+
Sbjct: 2523 SSCRAQDEFECANGECISFSLTCDGVSHCKDKSDEKPSYCNSRRCKKTFRQCNNGRCVSN 2582
Query: 286 QWQC----------DTYTWHSVSC------------IAEYQRCDNITDCADGSDEKDCPA 399
C D + +C I RC+ DC D SDE +C
Sbjct: 2583 MLWCNGVDDCGDGSDEIPCNKTACGVGEFRCRDGSCIGNSSRCNQFVDCEDASDEMNC-- 2640
Query: 400 STVDCSS------QNVFM--CADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQY 555
S DCSS + V C C+ S CDG DC D SDE+D C
Sbjct: 2641 SATDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDERDCPGVKRPRCPLN 2700
Query: 556 QFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYY 735
F C +CI SW CD DC +G DE +F C+ +F+C+N RC +++ CD
Sbjct: 2701 YFAC-PSGRCIPMSWTCDKEDDCENGEDETHCNKF--CSEAQFECQNHRCISKQWLCDGS 2757
Query: 736 DDCGDNSDE-DECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADE 882
DDCGD SDE C C P ++CPGT C+ + LCDG KDC DGADE
Sbjct: 2758 DDCGDGSDEAAHCEGKTCGPSSFSCPGTHVCVPERWLCDGDKDCTDGADE 2807
Score = 132 bits (333), Expect = 2e-28
Identities = 84/242 (34%), Positives = 106/242 (43%), Gaps = 14/242 (5%)
Frame = +1
Query: 430 FMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCD 609
F CA+ R C KCDG DC D SDE + HT C +F+C + +CI W+CD
Sbjct: 860 FACANNR-CIQERWKCDGDNDCLDNSDEAPALCHQHT-CPSDRFKC-ENNRCIPNRWLCD 916
Query: 610 GSKDCADGSDEPD-TCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDED-ECGEYR 783
G DC + DE + TC + C N+F C + RC P + CD DDCGD SDE C
Sbjct: 917 GDNDCGNSEDESNATCSARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPT 976
Query: 784 CPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECT 963
C P G CI+ CD DC D +DE AGC S +
Sbjct: 977 CFPLTQFTCNNGRCININWRCDNDNDCGDNSDE--------------AGCSHSCSSTQFK 1022
Query: 964 CPSGYKLDDRFHRTCSDINECAEFGYCDQLCAN------------HRPGFTCSCLGDCFT 1107
C SG + + H TC N+C + Y D+ AN H F C G C
Sbjct: 1023 CNSGRCIPE--HWTCDGDNDCGD--YSDETHANCTNQATRPPGGCHSDEFQCRLDGLCIP 1078
Query: 1108 LQ 1113
L+
Sbjct: 1079 LR 1080
Score = 112 bits (280), Expect = 3e-22
Identities = 153/619 (24%), Positives = 230/619 (36%), Gaps = 29/619 (4%)
Frame = +1
Query: 7198 CQ-ITDNLRKSPCTQLCFATPGTQTPTCSCARGVLKGR-TC--EEPDTYIMFSDGDKIID 7365
CQ I + LR C+QLC T G CSCAR +K TC E + +++ D I
Sbjct: 3823 CQDINECLRFGTCSQLCNNTKGGHL--CSCARNFMKTHNTCKAEGSEYQVLYIADDNEIR 3880
Query: 7366 VAIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAENPRL 7545
++ E + DV V RVY+ G IS+ S+ A P
Sbjct: 3881 SLFPGHPHSAYEQTFQGDESVRIDAMDVHVKAGRVYWT-NWHTGT-ISYRSLPPAAPP-- 3936
Query: 7546 VFGASKQPHAKEIR------HISDMKL------DWLTQKIYFTTGRGGKVMAIDTAGEHL 7689
+ H ++I +IS +K+ DW+ +Y+T + GE+
Sbjct: 3937 ---TTSNRHRRQIDRGVTHLNISGLKMPRGIAIDWVAGNVYWTDSGRDVIEVAQMKGENR 3993
Query: 7690 STIASG--DWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESIS 7863
T+ SG D +A+ +DP G ++WSD G P+IE + + G R+ +V ++I
Sbjct: 3994 KTLISGMIDEPHAIVVDPLRGTMYWSDWGN-------HPKIETAAMDGTLRETLVQDNIQ 4046
Query: 7864 LPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGYRAKS----LDIWDRWLYMS 8031
P +AVD+ N+++YWAD I +G + V A R S +D+++ ++Y
Sbjct: 4047 WPTGLAVDYHNERLYWADAKLSVIGSIRLNGTDPIVAADSKRGLSHPFSIDVFEDYIYGV 4106
Query: 8032 DPLSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNG 8211
++N VF+I K S L N+ + SDV +Q + C D
Sbjct: 4107 TYINNRVFKIHKFGHSPLINLTGG---------LSHASDVVLYHQHKQPEVTNPC--DRK 4155
Query: 8212 GCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSEPAKECLP-PY 8388
C+ LC L+ S C+C + L D T CV S + P P
Sbjct: 4156 KCEWLCL-------LSPSGPVCTCPNGKRL------DNGT-CVPVPSPTPPPDAPRPGTC 4201
Query: 8389 NFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHI 8568
QC +G L A K C P Y + C +C +
Sbjct: 4202 TLQCFNGGSCFLNARRQPKCRC------QPRYTGDK--------CELDQCWEYCHNGGTC 4247
Query: 8569 DDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPGLP 8748
G CP+ + T G+C N ++ C Q + PG
Sbjct: 4248 AASPSGMPTCRCPTGFTGPKCTAQVCAGYCSN-------NSTCTVNQGNQPQCRCLPGFL 4300
Query: 8749 ID------CRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPS 8910
D C G C N C AD G C C +C+ RC
Sbjct: 4301 GDRCQYRQCSGF---CENFGTCQMAAD---GSRQCRCTVYFEGPRCEVNKCS----RCLQ 4350
Query: 8911 GRCIPETWQCDGDNDCSDG 8967
G C+ D +C+DG
Sbjct: 4351 GACVVNKQTGDVTCNCTDG 4369
Score = 108 bits (270), Expect = 4e-21
Identities = 88/282 (31%), Positives = 119/282 (41%), Gaps = 23/282 (8%)
Frame = +1
Query: 325 CIAEYQRCDNITDCADG---SDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDC 495
C+ +Q N + C G ++ C A C +Q+ F CA+G +C S CDG C
Sbjct: 2494 CLLTHQGHVNCS-CRGGRILQEDFTCRAVNSSCRAQDEFECANG-ECISFSLTCDGVSHC 2551
Query: 496 RDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTA 675
+D SDEK S N C + FR + +C+ C+G DC DGSDE C C
Sbjct: 2552 KDKSDEKPSYC-NSRRC-KKTFRQCNNGRCVSNMLWCNGVDDCGDGSDE-IPCNKTACGV 2608
Query: 676 NEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPG---------KWNCPGTGHCI 828
EF+C++ C RC+ + DC D SDE C C C T C
Sbjct: 2609 GEFRCRDGSCIGNSSRCNQFVDCEDASDEMNCSATDCSSYFRLGVKGVLFQPCERTSLCY 2668
Query: 829 DQLKLCDGSKDCADGADEQQC---SQNLCP--SLGCQAG-CHPSPH--GGECTCPSGYKL 984
+CDG+ DC D +DE+ C + CP C +G C P E C +G
Sbjct: 2669 APSWVCDGANDCGDYSDERDCPGVKRPRCPLNYFACPSGRCIPMSWTCDKEDDCENG--- 2725
Query: 985 DDRFHRTCSDINECAEFGYCDQLCANHR---PGFTCSCLGDC 1101
+D H C+ A+F C NHR + C DC
Sbjct: 2726 EDETH--CNKFCSEAQFE-----CQNHRCISKQWLCDGSDDC 2760
Score = 106 bits (264), Expect = 2e-20
Identities = 59/172 (34%), Positives = 78/172 (45%)
Frame = +1
Query: 391 CPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCA 570
C + CS+ + G +C C + L + +C N TA QF C
Sbjct: 3295 CKVNNGGCSNLCLLSPGGGHKC-----ACPTNFY---LGGDGRTCVSNCTAS---QFVCK 3343
Query: 571 DKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGD 750
+ +CI W CD DC D SDEP C KC +FQC C F CD +DC D
Sbjct: 3344 ND-KCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQFQCSTGICTNPAFICDGDNDCQD 3402
Query: 751 NSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLC 906
NSDE C + C P ++ C T CI + C+G +C DG DE+ C + C
Sbjct: 3403 NSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTC 3454
Score = 67.4 bits (163), Expect = 1e-08
Identities = 43/129 (33%), Positives = 56/129 (43%), Gaps = 19/129 (14%)
Frame = +1
Query: 610 GSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKF------------RCDYYDDCGDN 753
GS+ CA D+ + C AN +CQP +F +CD +DC DN
Sbjct: 824 GSRQCACAEDQVLDTDGVTCLANPSYVPPPQCQPGEFACANNRCIQERWKCDGDNDCLDN 883
Query: 754 SDEDE--CGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQ--CSQNLCP--SL 915
SDE C ++ CP ++ C CI LCDG DC + DE CS CP
Sbjct: 884 SDEAPALCHQHTCPSDRFKCE-NNRCIPNRWLCDGDNDCGNSEDESNATCSARTCPPNQF 942
Query: 916 GCQAG-CHP 939
C +G C P
Sbjct: 943 SCASGRCIP 951
Score = 47.0 bits (110), Expect = 0.014
Identities = 31/102 (30%), Positives = 42/102 (40%), Gaps = 10/102 (9%)
Frame = +1
Query: 8746 PIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMN---QQCAQHYVRC-PSG 8913
P C + C + CI CDG DC D +DE C Q+C + C +
Sbjct: 25 PKTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEHSCLGTE 84
Query: 8914 RCIPETWQCDGDNDCSDGWD------ETHTNCTDTAGKKICV 9021
C+P + C+G DC DG D E NC+ + CV
Sbjct: 85 LCVPMSRLCNGIQDCMDGSDEGAHCRELRANCSRMGCQHHCV 126
Score = 46.2 bits (108), Expect = 0.023
Identities = 62/231 (26%), Positives = 87/231 (36%), Gaps = 29/231 (12%)
Frame = +1
Query: 9142 TCTDQEFH---CTSNAKLAQPKYECIPR----------AW-LCDGDVTCAGGEDESTELC 9279
TCT Q F+ C NA+ QPK C PR W C TCA C
Sbjct: 4200 TCTLQCFNGGSCFLNAR-RQPKCRCQPRYTGDKCELDQCWEYCHNGGTCAASPS-GMPTC 4257
Query: 9280 KTEKKECNKGEF--RCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFF--QCAN 9447
+ C G +C+ Q C C ++ C C C P F +C
Sbjct: 4258 R-----CPTGFTGPKCTAQVC---AGYCSNNSTCTVNQGNQPQCR---CLPGFLGDRCQY 4306
Query: 9448 HKCVPNSWKCDGNDDCE---DGSDEKDCPKNSASAQ-KASKCSNGQFQCTSGECIDDAKV 9615
+C S C+ C+ DGS + C + + +KCS +C G C+ + +
Sbjct: 4307 RQC---SGFCENFGTCQMAADGSRQCRCTVYFEGPRCEVNKCS----RCLQGACVVNKQT 4359
Query: 9616 CDRNFDCTD-RSDESSLCFIDECS------LAEKPLCEQKCMDMKIGYKCD 9747
D +CTD R S L ID CS + K + E +C G +C+
Sbjct: 4360 GDVTCNCTDGRVAPSCLTCIDHCSNGGSCTMNSKMMPECQCPPHMTGPRCE 4410
>gi|15825096|gb|AAL09567.1| lipoprotein receptor-related protein [Mus
musculus]
Length = 4545
Score = 2029 bits (5257), Expect = 0.0
Identities = 1389/4508 (30%), Positives = 2101/4508 (45%), Gaps = 174/4508 (3%)
Frame = +1
Query: 661 KKCTANEFQCKNK-RCQPRKFRCDYYDDCGDNSDE-----DECGEYRCPPGKWNCPGTGH 822
K C+ +F C+++ C + +RCD DC D SDE + RCPP + +C GT
Sbjct: 26 KTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEHSCLGTEL 85
Query: 823 CIDQLKLCDGSKDCADGADEQQCSQNL---CPSLGCQAGCHPSPHGGECTCPSGYKLDDR 993
C+ +LC+G +DC DG+DE + L C +GCQ C P+P G C C S ++L
Sbjct: 86 CVPMSRLCNGIQDCMDGSDEGAHCRELRANCSRMGCQHHCVPTPSGPTCYCNSSFQLQAD 145
Query: 994 FHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNN 1173
+TC D +EC+ +G C QLC N FTC C+ + + LQ DN + C + N
Sbjct: 146 -GKTCKDFDECSVYGTCSQLCTNTDGSFTCGCV-EGYLLQ------PDNRS----CKAKN 193
Query: 1174 ADKMK---LFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSA 1344
+ L +A + + S +DF Y + + W + SA
Sbjct: 194 EPVDRPPVLLIANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWV-HVGDSA 252
Query: 1345 FSADVD-----------DEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDV 1491
+ DE I+ +SL SL + +A+DW+T Y ++ RI V
Sbjct: 253 AQTQLKCARMPGLKGFVDEHTIN----ISL-SLHHVEQMAIDWLTGNFYFVDDIDDRIFV 307
Query: 1492 SSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTNQ---LKLEAAAMDGTNRRTLVNTHT 1662
+ +G+ LL L P IALDP G++FFT+ K+E MDG NR LV++
Sbjct: 308 CNRNGDTCVTLLDLELYNPKGIALDPAMGKVFFTDYGQIPKVERCDMDGQNRTKLVDSKI 367
Query: 1663 HQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYW 1842
GI +D+ ++ VYW D +D +E +DY+G R+ + QG+ ++ H +GL +F+ YLY
Sbjct: 368 VFPHGITLDLVSRLVYWADAYLDYIEVVDYEGKGRQTIIQGI-LIEHLYGLTVFENYLYA 426
Query: 1843 TD------WTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMK 2004
T+ + VI+V +F S + + + + YH QP C +
Sbjct: 427 TNSDNANTQQKTSVIRVNRFNSTEYQVVTRVDKGG---ALHIYHQRRQPRVRSHACENDQ 483
Query: 2005 IENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKL-VNGKRCIDSIDYLLFSSNK--- 2172
P C +C+L+ + C C G L +GK C L K
Sbjct: 484 YGKP---GGCSDICLLANSHKA----RTCRCRSGFSLGSDGKSCKKPEHELFLVYGKGRP 536
Query: 2173 -IVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFF--YADIMDNTIYRI 2343
I+RG+ ++ K E ++PI + R D H + F +AD I R
Sbjct: 537 GIIRGM--DMGAKVPDEHMIPIENLMNPRA-------LDFHAETGFIYFADTTSYLIGRQ 587
Query: 2344 RPDGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDN-IRNSLEVVKIGETGLVHPDELVRR 2520
+ DG +L + ++ DW+ LY+ D+ + ++ V ++ + R+
Sbjct: 588 KIDGTERETILKDGIHNVEGVAVDWMGDNLYWTDDGPKKTISVARLEKAAQT------RK 641
Query: 2521 QLIT-ELRDPVSVVVHPWKGLLFYAE------AMRPAAIYRCHIDGQNCQV-IRNTTLGR 2676
LI ++ P ++VV P G +++ + R + R +DG + + + + T+
Sbjct: 642 TLIEGKMTHPRAIVVDPLNGWMYWTDWEEDPKDSRRGRLERAWMDGSHRDIFVTSKTVLW 701
Query: 2677 PSEMAIDFAENRLCWGDTLLKTISCMDFDG--KNVVKLDIDNPIPVAITIMNEYIYYVHQ 2850
P+ +++D RL W D I + +G + +V + + Y+++
Sbjct: 702 PNGLSLDIPAGRLYWVDAFYDRIETILLNGTDRKIVYEGPELNHAFGLCHHGNYLFWTEY 761
Query: 2851 RPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQ--CTQ 3024
R S+ R+ + G V ++ IF ++ Q Q + + CR + C+
Sbjct: 762 RSGSVYRLERGVAGAPPTVTLLRSERPPIFEIRMYDAQQQQVGTNK----CRVNNGGCSS 817
Query: 3025 LCFATPSESHPNELEAKCACRQGFMINKENNHSCQKDPAEKIEQLCSSNSTQFQCKNGRC 3204
LC ATP +CAC + +++ + +C +P+ C +F C N RC
Sbjct: 818 LCLATPGSR-------QCACAEDQVLDTDGV-TCLANPSYVPPPQCQPG--EFACANNRC 867
Query: 3205 IPKEWKCDGENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKKCIPAQXXXXXXXXXX 3384
I + WKCDG+NDCLD SDE C ++T
Sbjct: 868 IQERWKCDGDNDCLDNSDEAPAL---------CHQHT----------------------- 895
Query: 3385 XXXXXXVKYCKDGQKPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNATCA 3564
C + +F+C+N+RCIP +W E C TC
Sbjct: 896 -----------------CPSDRFKCENNRCIPNRWLCDGDNDCGNSEDESNATCSARTCP 938
Query: 3565 ANQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQCVPLRNHX 3744
NQFSCA+GRCIPI W CD D+DC D +DE P QF C NGR C+ N
Sbjct: 939 PNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNGR-CI---NIN 994
Query: 3745 XXXXXXXXXXXXXXXAVTAESCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCT 3924
A + SC+ QFKC +SG CIP W SDE CT
Sbjct: 995 WRCDNDNDCGDNSDEAGCSHSCSSTQFKC-NSGRCIPEHWTCDGDNDCGDYSDETHANCT 1053
Query: 3925 SGRQ-----CSSDQFKCG-NGRCILNNWLCDGENDCGDGSDESS------------ERGC 4050
+ C SD+F+C +G CI W CDG+ DC D SDE S + GC
Sbjct: 1054 NQATRPPGGCHSDEFQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPNVKFGC 1113
Query: 4051 KTSMN------------------------ARKCPFEHVACENDQETCIPLHQLCDGKTHC 4158
K S A C C N+ C+P +LCDGK C
Sbjct: 1114 KDSARCISKAWVCDGDSDCEDNSDEENCEALACRPPSHPCANNTSVCLPPDKLCDGKDDC 1173
Query: 4159 PGGTDEGGRCARDLCSADRAGCSFKCHNSPN-GPICSCPFGEQLVNKTK-CEPENECLDS 4332
G+DEG C D CS + GCS C +P G +CSCP G +L + C+ ++ C
Sbjct: 1174 GDGSDEGELC--DQCSLNNGGCSHNCSVAPGEGIVCSCPLGMELGSDNHTCQIQSYCAKH 1231
Query: 4333 SSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNW 4512
CSQ+C K CSC EG+ L+ D +C+ D K I+ SNR+ I D ++
Sbjct: 1232 LKCSQKCDQNKFSVKCSCYEGWVLEPDGESCRSLDPFKPFIIF-SNRHEIRRIDLHKGDY 1290
Query: 4513 HTFGAIVENAIALAWDSLTDRIYWSDIREKKI----LSANRNGTNATVFIADGLDITEGI 4680
+ N IAL + +YW+D+ E KI L N T+ V I GL EG+
Sbjct: 1291 SVLVPGLRNTIALDFHLSQSALYWTDVVEDKIYRGKLLDNGALTSFEVVIQYGLATPEGL 1350
Query: 4681 ALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQ 4860
A+DW+ N+YWV+S+L+ IEVA L D RT L+ ++ PR IA+DPR G++FWTDW
Sbjct: 1351 AVDWIAGNIYWVESNLDQIEVAKL-DGTLRTTLLAGDIEHPRAIALDPRDGILFWTDWDA 1409
Query: 4861 N-PCIERASMDGTDRQIIVKTKIY--WPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGR 5031
+ P IE ASM G R+ I + WPN + +DY R+ + D++ D I YDGSG
Sbjct: 1410 SLPRIEAASMSGAGRRTIHRETGSGGWPNGLTVDYLEKRILWIDARSDAIYSARYDGSGH 1469
Query: 5032 TQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVA 5211
+VL +F+ HP A+ ++ +Y++D R L K+ G T ++ +
Sbjct: 1470 MEVLRGHEFLSHPFAVTLYGGEVYWTDWRTNTLAKANKW-TGHNVTVVQRTNTQPFDLQV 1528
Query: 5212 VHPVLQPVIKNNPCSTN----PCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKPFL 5379
HP QP+ N PC N PCSHLCL+N T +C CP KL C + K FL
Sbjct: 1529 YHPSRQPMAPN-PCEANGGRGPCSHLCLINYNRTVSCACPHLMKLHKDNTTCYE-FKKFL 1586
Query: 5380 VIIQKTNVFGIEMNSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTL 5559
+ ++ + G+++++ +++ VP + N YDA + ++ +
Sbjct: 1587 LYARQMEIRGVDLDAPYYNY--IISFTVP--DIDNVTVLDYDAREQRVYWSD-------- 1634
Query: 5560 AQITTDSAIYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKIT--QTIEIIRT 5733
AI R+ +NG + S+ +P+ A+ L DW RNL + T + I + R
Sbjct: 1635 ---VRTQAIKRAFINGTGVETVVSADLPN-AHGLAVDWVSRNLFWTSYDTNKKQINVARL 1690
Query: 5734 QGKQYRSVILSNDQSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLV 5913
G +V+ +Q +G ++W D ++ A +DGSN +
Sbjct: 1691 DGSFKNAVVQGLEQPHGLVVHPL-------RGKLYWTDGDN------ISMANMDGSNHTL 1737
Query: 5914 IASNDLAELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGR--QPNGLAFY 6087
+ S + +AID +++Y+ + I+ DG + + + + + LA
Sbjct: 1738 LFSGQKGPVG-LAIDFPESKLYWISSGNHTINRCNLDGSELEVIDTMRSQLGKATALAIM 1796
Query: 6088 GDRLFYADSAFDSIEVATINGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHINNG 6267
GD+L++AD + + S + V ++ +PC +NNG
Sbjct: 1797 GDKLWWADQVSEKMGTCNKADGSGSVVLRNSTTLVMHMKVYDESIQLEHEGTNPCSVNNG 1856
Query: 6268 NCDHICIPLMFAQRTCTCANGY-VKDGQTSCKLFDESFVIVATKTKVIGYPIDETQSKGV 6444
+C +C+P R+C C GY ++ GQ +C+ SF++ + + G P+D K
Sbjct: 1857 DCSQLCLPTSETTRSCMCTAGYSLRSGQQACEGVG-SFLLYSVHEGIRGIPLDPND-KSD 1914
Query: 6445 AMEPIGGLSIT-GVDYDYESKTIYVAEA--SGINKGITAYTIGESSPRAVIRDSIGSLTI 6615
A+ P+ G S+ G+D+ E+ TIY + S I++ T E V+ + IG +
Sbjct: 1915 ALVPVSGTSLAVGIDFHAENDTIYWVDMGLSTISRAKRDQTWRED----VVTNGIGR--V 1968
Query: 6616 KSLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWA 6795
+ +A+DWI N+Y+ + + IEV++L+G++R ++++ + P +I V P YL+W
Sbjct: 1969 EGIAVDWIAGNIYWTDQGFDV--IEVARLNGSFRYVVISQGLDKPRAITVHPEKGYLFWT 2026
Query: 6796 DQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVR-STGG 6972
+ G P I+RS LDG+ R V+V+ I+ P + VD +YW DA+MD I R+ TG
Sbjct: 2027 EWGHYPRIERSRLDGTERVVLVNVSISWPNGISVDYQGGKLYWCDARMDKIERIDLETGE 2086
Query: 6973 TPELV-RSDIASAAGVALHGQNMYWTDN-RLEKLFRATSKPNQTSLLLSPTTVAASLKDI 7146
E+V S+ V++ +YW+D + K N T + T + LKDI
Sbjct: 2087 NREVVLSSNNMDMFSVSVFEDFIYWSDRTHANGSIKRGCKDNATDSVPLRTGIGVQLKDI 2146
Query: 7147 GDVAVFSSNNQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCARGVLK--GRTCEE 7320
VF+ + Q + ++ C + + C QLC G Q C+CA G+L G +C E
Sbjct: 2147 ---KVFNRDRQ-KGTNVCAVANG----GCQQLCLYRGGGQR-ACACAHGMLAEDGASCRE 2197
Query: 7321 PDTYIMFSDGDKIIDVAIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGV 7500
Y+++S+ + + + + + P++ PF + +++ + L Y SP
Sbjct: 2198 YAGYLLYSERTILKSIHLSDERNLNAPVQ-PFEDPEHMKNV---IALAFDYRAGTSPGTP 2253
Query: 7501 NISWFSMNNAENPRLVF--GASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVM--AI 7668
N +FS + N + + G+ + + + + + +Y+T+ + +
Sbjct: 2254 NRIFFSDIHFGNIQQINDDGSGRTTIVENVGSVEGLAYHRGWDTLYWTSYTTSTITRHTV 2313
Query: 7669 DTAG------EHLSTIASGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGG 7830
D E + T++ D A +D C L+FW T+ P I R+ L+G
Sbjct: 2314 DQTRPGAFERETVITMSGDDHPRAFVLDECQNLMFW------TNWNELHPSIMRAALSGA 2367
Query: 7831 SRKVIVSESISLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGYRAK--SLD 8004
+ ++ + I P +A+D R +K+Y++D IE +YDG +R VI L
Sbjct: 2368 NVLTLIEKDIRTPNGLAIDHRAEKLYFSDATLDKIERCEYDGSHRYVILKSEPVHPFGLA 2427
Query: 8005 IWDRWLYMSDPLSNGVFRIDKESGSGLENVVSDRRIPGA-LRVFASESDVRTRNQVCNAL 8181
++ ++ +D + V R +K GS ++ + D IP + + A +D N+
Sbjct: 2428 VYGEHIFWTDWVRRAVQRANKYVGSDMKLLRVD--IPQQPMGIIAVANDT-------NSC 2478
Query: 8182 TSQLCKTDNGGCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSE 8361
C+ +NGGC LC + V CSC G+ R NS
Sbjct: 2479 ELSPCRINNGGCQDLCLLTHQ------GHVNCSCRG--------GRILQEDFTCRAVNSS 2524
Query: 8362 PAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCI 8541
C F+C +G CI TCD C D SDE P+YCN+R C + + C N RC+
Sbjct: 2525 ----CRAQDEFECANGECISFSLTCDGVSHCKDKSDEKPSYCNSRRCKKTFRQCNNGRCV 2580
Query: 8542 DSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDE 8721
+ CN +DDCGDGSDE+ C + AC G F C +G CI + C+ DC D SDE
Sbjct: 2581 SNMLWCNGVDDCGDGSDEIPC-NKTACGVGEFRCRDGSCIGNSSRCNQFVDCED--ASDE 2637
Query: 8722 ---SLATCPG-LPIDCRGVKVR-CPNTNICIQPADLCDGYDDCGDKADENQLFCMNQ-QC 8883
S C + +GV + C T++C P+ +CDG +DCGD +DE + + +C
Sbjct: 2638 MNCSTTDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDERDCPGVKRPRC 2697
Query: 8884 AQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCIS 9063
+Y CPSGRCIP +W CD ++DC +G DETH N K C + F+C N +CIS
Sbjct: 2698 PLNYFACPSGRCIPMSWTCDKEDDCENGEDETHCN-------KFC-SEAQFECQNHRCIS 2749
Query: 9064 RAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVT 9243
+ ++ + C +TC F C + C+P WLCDGD
Sbjct: 2750 KQWLCDGSDDCGDGSDEAAH--CEGKTCGPSSFSCPGT-------HVCVPERWLCDGDKD 2800
Query: 9244 CAGGEDESTELCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQ 9423
C G DES C+ EF C N+ CI + CD D DC DGSDE C Y +C
Sbjct: 2801 CTDGADESVTAGCLYNSTCDDREFMCQNRLCIPKHFVCDHDRDCADGSDESPECEYPTCG 2860
Query: 9424 PDFFQCANHKCVPN-SWKCDGNDDCEDGSDEKDCPKNSASAQKASKCS-NGQFQCTSGEC 9597
P+ F+CAN +C+ + W+CDG +DC D SDE PKN KC+ + QF C+SG C
Sbjct: 2861 PNEFRCANGRCLSSRQWECDGENDCHDHSDE--APKNPHCTSPEHKCNASSQFLCSSGRC 2918
Query: 9598 IDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDIS 9777
+ +A +C+ DC D SDE C ++EC + C Q C D+KIG+KC C GF +
Sbjct: 2919 VAEALLCNGQDDCGDGSDERG-CHVNECLSRKLSGCSQDCEDLKIGFKCRCRPGFRLK-D 2976
Query: 9778 DQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQ-LSSDDHSCKRTEMEPEPFFLL 9954
D ++C +++EC CSQ C + GSYKC CV+GY D HSCK E EPF +
Sbjct: 2977 DGRTCADLDECSTTFP-CSQLCINTHGSYKCLCVEGYAPRGGDPHSCKAVTDE-EPFLIF 3034
Query: 9955 ANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLID---QGKLRLLRVDLDEMD 10125
AN++Y+RK+++DG+ Y L QG +N V+LD D E+ Y D QG + + R+ L+
Sbjct: 3035 ANRYYLRKLNLDGSNYTLLKQGLNNAVALDFDYREQMIYWTDVTTQGSM-IRRMHLNG-- 3091
Query: 10126 SPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQP 10305
S+ + + R + +G+AVDWVG LY ++ +I V +L+G + L+ +++P
Sbjct: 3092 ---SNVQVLHRTGLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVSSGLREP 3148
Query: 10306 KAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDR 10485
+A+VV GYL++T+W IGRI +DGS + + + WPN + +DY ++R
Sbjct: 3149 RALVVDVQNGYLYWTDWGDHSLIGRIGMDGSGRSI-----IVDTKITWPNGLTVDYVTER 3203
Query: 10486 LFWGDAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTG 10665
++W DA + I F DG+ R + +Q H+ ++ +F+DY+YW DW + + R K TG
Sbjct: 3204 IYWADAREDYIEFASLDGSNRHVVLSQDIPHIFALTLFEDYVYWTDWETKSINRAHKTTG 3263
Query: 10666 KNETILKKTVQLPNDLRIVHPMRQPAYPN-PCGDNNGGCSHLCLIGAGGNGYTCSCPDQF 10842
N+T+L T+ P DL + H +RQP PN PC NNGGCS+LCL+ GG G+ C+CP F
Sbjct: 3264 ANKTLLISTLHRPMDLHVFHALRQPDVPNHPCKVNNGGCSNLCLLSPGG-GHKCACPTNF 3322
Query: 10843 VLLSDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVG 11022
L D +TC NCT QF C D KCIP W CD E DC D SDEP + C + C G
Sbjct: 3323 YLGGDGRTCVSNCTASQFVCKND--KCIPFWWKCDTEDDCGDHSDEPPD--CPEFKCRPG 3378
Query: 11023 EFQCTNHNCTRPFQIXXXXXXXXXXXXEQNCD-KACDPWMFKCAATGRCIPRRFTXXXXX 11199
+FQC+ CT P I E NCD C P FKC T RCIP F
Sbjct: 3379 QFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQD 3438
Query: 11200 XXXXRSDEADTLCMSAERNCTAEEFRCN-NNKCIAKAWRXXXXXXXXXXXXETPECAQIE 11376
DE D E C +F+C+ +CI + W E C Q+
Sbjct: 3439 NCGDGEDERD----CPEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQMT 3494
Query: 11377 CKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCP--TCDDVGEFRCATSGKCIPR 11550
C RC S RCIP C+G+DDC D SDE K+ C TC+ +FRC + +C+P
Sbjct: 3495 CGVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPY-QFRC-KNNRCVPG 3552
Query: 11551 RWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDES 11730
RW CD +NDCGDNSDE SC T RPCSESEF C +G+CI G CDG C+DG DE
Sbjct: 3553 RWQCDYDNDCGDNSDE--ESC--TPRPCSESEFSCANGRCIAGRWKCDGDHDCADGSDEK 3608
Query: 11731 QCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFECANSV 11910
CT RC QC G CI CD DC + +DE C RTC EF+C N++
Sbjct: 3609 DCT-PRCDMDQFQCKSGHCIPLRWRCDADADCMDGSDEEAC-GTGVRTCPLDEFQCNNTL 3666
Query: 11911 CIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPN 12090
C P + SDE EC C P FRC + R+CL I + C+G ++CG
Sbjct: 3667 CKPLAWKCDGEDDCGDNSDENPEECARFICPPNRPFRCKNDRVCLWIGRQCDGVDNCG-- 3724
Query: 12091 DFSDEHLSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKT 12270
D +DE + +F C N +C++ ++ C+ DDCGD SDE CS T
Sbjct: 3725 DGTDEEDCEPPTAQNPHCKDKKEFLCRNQRCLSSSLRCNMFDDCGDGSDEEDCSIDPKLT 3784
Query: 12271 SCEAFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTK 12450
SC + G + C YC CR GF P P C DI+EC TC+QLC NTK
Sbjct: 3785 SCATNASMCGDEARCVRTEKAAYCACRSGFHTVPGQP-GCQDINECLRFGTCSQLCNNTK 3843
Query: 12451 GSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGSGTNRHXXXXX 12630
G +LC C ++ T C+A+G V+ ADD+ ++ G + +
Sbjct: 3844 GGHLCSCARNF-------MKTHNTCKAEGSEYQVLYIADDNEIRSLFPGHPHSAYEQTFQ 3896
Query: 12631 XXXXXXXXXXXXXPRKELMYWIDGSERTI-YRS---AIANGNQSHEGQKLDVDFAAMGV- 12795
+ +YW + TI YRS A + +++D + +
Sbjct: 3897 GDESVRIDAMDVHVKAGRVYWTNWHTGTISYRSLPPAAPPTTSNRHRRQIDRGVTHLNIS 3956
Query: 12796 ---VPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYL 12966
+P IA+D+ GN++ ++ I V G
Sbjct: 3957 GLKMPRGIAIDWVAGNVYWTDSGRDV-----------------------IEVAQMKGENR 3993
Query: 12967 KKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAI 13146
K +++G + +P A++ P G + +SD G H KIE A MDGT R+ +V+D + PT +A+
Sbjct: 3994 KTLISGMIDEPHAIVVDPLRGTMYWSDWGNHPKIETAAMDGTLRETLVQDNIQWPTGLAV 4053
Query: 13147 DEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRH---IPYAVDVFENHIYWLSRESKT 13317
D R+YW D K + ++ ++G++ + P+++DVFE++IY ++ +
Sbjct: 4054 DY-HNERLYWADAKLSVIGSIRLNGTDPIVAADSKRGLSHPFSIDVFEDYIYGVTYINNR 4112
Query: 13318 LYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTGFA 13497
++ KFG + L L H V + + C+R +C LC+ PS G
Sbjct: 4113 VFKIHKFGHSPLINLTGGL--SHASDVVLYHQHKQPEVTNPCDRKKCEWLCLLSPS-GPV 4169
Query: 13498 CLCPDGIVPQLD-GSCATQHVEALTMPKQC--------KCTNGGKCRLDG----SCECTS 13638
C CP+G +LD G+C V + T P +C NGG C L+ C C
Sbjct: 4170 CTCPNG--KRLDNGTCVP--VPSPTPPPDAPRPGTCTLQCFNGGSCFLNARRQPKCRCQP 4225
Query: 13639 DFEGDQCE 13662
+ GD+CE
Sbjct: 4226 RYTGDKCE 4233
Score = 360 bits (925), Expect = 4e-97
Identities = 283/1025 (27%), Positives = 442/1025 (42%), Gaps = 25/1025 (2%)
Frame = +1
Query: 130 ASVNTASSVCNENDFRCNDGKCIRTEWX-XXXXXXXXXXXXXXXXPHPGCKSDQWQCDTY 306
++ ++ C N F C G+CI W +P C + +
Sbjct: 928 SNATCSARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPTC----FPLTQF 983
Query: 307 TWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGK 486
T ++ CI RCDN DC D SDE C S CSS F C GR C CDG
Sbjct: 984 TCNNGRCININWRCDNDNDCGDNSDEAGCSHS---CSSTQ-FKCNSGR-CIPEHWTCDGD 1038
Query: 487 YDCRDLSDEKD-SCSRNHT----ACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDT 651
DC D SDE +C+ T C +F+C CI W CDG DC D SDE +
Sbjct: 1039 NDCGDYSDETHANCTNQATRPPGGCHSDEFQCRLDGLCIPLRWRCDGDTDCMDSSDE-KS 1097
Query: 652 CE--FKKCTAN-EFQCKNK-RCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCP-GT 816
CE C N +F CK+ RC + + CD DC DNSDE+ C C P C T
Sbjct: 1098 CEGVTHVCDPNVKFGCKDSARCISKAWVCDGDSDCEDNSDEENCEALACRPPSHPCANNT 1157
Query: 817 GHCIDQLKLCDGSKDCADGADE-QQCSQNLCPSLGCQAGCHPSP-HGGECTCPSGYKLDD 990
C+ KLCDG DC DG+DE + C Q + GC C +P G C+CP G +L
Sbjct: 1158 SVCLPPDKLCDGKDDCGDGSDEGELCDQCSLNNGGCSHNCSVAPGEGIVCSCPLGMELGS 1217
Query: 991 RFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSN 1170
H TC + CA+ C Q C ++ CSC + + L+ + G+ C S
Sbjct: 1218 DNH-TCQIQSYCAKHLKCSQKCDQNKFSVKCSCY-EGWVLEPD---GES-------CRSL 1265
Query: 1171 NADKMKLFVARREGLYRLNPKNPDEEVKKLASG-EFIYGIDFDYGDRKIFWTDRLAHSAF 1347
+ K + + R + R++ D V L G +DF ++WTD + +
Sbjct: 1266 DPFKPFIIFSNRHEIRRIDLHKGDYSV--LVPGLRNTIALDFHLSQSALYWTDVVEDKIY 1323
Query: 1348 SADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLL 1527
+ D G ++ + + L P LAVDWI +Y +ES +I+V+ DG RT LL
Sbjct: 1324 RGKLLDNGALTSFEVVIQYGLATPEGLAVDWIAGNIYWVESNLDQIEVAKLDGTLRTTLL 1383
Query: 1528 ADGLTLPLDIALDPLRGEMFFT----NQLKLEAAAMDGTNRRTLVNTHTHQ---VSGIVV 1686
A + P IALDP G +F+T + ++EAA+M G RRT ++ T +G+ V
Sbjct: 1384 AGDIEHPRAIALDPRDGILFWTDWDASLPRIEAASMSGAGRRT-IHRETGSGGWPNGLTV 1442
Query: 1687 DITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGV 1866
D KR+ W+D + D + S Y G+ V +G + HPF + L+ +YWTDW +
Sbjct: 1443 DYLEKRILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYGGEVYWTDWRTNTL 1502
Query: 1867 IQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMC 2046
+ K+ + T N P + YHP QP + C A PC++ +C
Sbjct: 1503 AKANKWTGHNVTVVQRT--NTQPFDLQVYHPSRQP-MAPNPCEANGGRGPCSH-----LC 1554
Query: 2047 ILSKDNGGFGVGYKCACPIGQKL-VNGKRCIDSIDYLLFSSNKIVRGIFPEINEKALAEA 2223
+++ + CACP KL + C + +LL++ +RG+ + A
Sbjct: 1555 LIN-----YNRTVSCACPHLMKLHKDNTTCYEFKKFLLYARQMEIRGVDLD------APY 1603
Query: 2224 VLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFS 2403
I + I ++ D +++D+ I R +G G V+
Sbjct: 1604 YNYIISFTVPDIDNVTVLDYDAREQRVYWSDVRTQAIKRAFINGTGVETVVSADLPNAHG 1663
Query: 2404 MSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKGLL 2583
++ DW+S+ L++ N ++ + D + ++ L P +VVHP +G L
Sbjct: 1664 LAVDWVSRNLFWTSYDTNKKQI------NVARLDGSFKNAVVQGLEQPHGLVVHPLRGKL 1717
Query: 2584 FYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFD 2763
++ + I ++DG N ++ + G P +AIDF E++L W + TI+ + D
Sbjct: 1718 YWTDGDN---ISMANMDGSNHTLLFSGQKG-PVGLAIDFPESKLYWISSGNHTINRCNLD 1773
Query: 2764 GKNVVKLDIDNP---IPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERS 2934
G + +D A+ IM + +++ Q + +K +G GS ++R
Sbjct: 1774 GSELEVIDTMRSQLGKATALAIMGDKLWWADQVSEKMGTCNKADGSGSVVLRN---STTL 1830
Query: 2935 IFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINKEN 3114
+ +K Q + + C+QLC T +E C C G+ + +
Sbjct: 1831 VMHMKVYDESIQLEHEGTNPCSVNNGDCSQLCLPT------SETTRSCMCTAGYSL-RSG 1883
Query: 3115 NHSCQ 3129
+C+
Sbjct: 1884 QQACE 1888
Score = 327 bits (839), Expect = 4e-87
Identities = 216/683 (31%), Positives = 311/683 (44%), Gaps = 21/683 (3%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAE 336
C N F C G+CI W + C Q++C + CI++
Sbjct: 2697 CPLNYFACPSGRCIPMSWTCDKEDDCENGEDETHC-NKFCSEAQFECQNHR-----CISK 2750
Query: 337 YQRCDNITDCADGSDEK-DCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDE 513
CD DC DGSDE C T SS F C C CDG DC D +DE
Sbjct: 2751 QWLCDGSDDCGDGSDEAAHCEGKTCGPSS---FSCPGTHVCVPERWLCDGDKDCTDGADE 2807
Query: 514 KDS--CSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQ 687
+ C N T C +F C ++ CI K +VCD +DCADGSDE CE+ C NEF+
Sbjct: 2808 SVTAGCLYNST-CDDREFMCQNRL-CIPKHFVCDHDRDCADGSDESPECEYPTCGPNEFR 2865
Query: 688 CKNKRC-QPRKFRCDYYDDCGDNSDE----DEC--GEYRCPPGKWNCPGTGHCIDQLKLC 846
C N RC R++ CD +DC D+SDE C E++C +G C+ + LC
Sbjct: 2866 CANGRCLSSRQWECDGENDCHDHSDEAPKNPHCTSPEHKCNASSQFLCSSGRCVAEALLC 2925
Query: 847 DGSKDCADGADEQQCSQNLCPS---LGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDI 1017
+G DC DG+DE+ C N C S GC C G +C C G++L D RTC+D+
Sbjct: 2926 NGQDDCGDGSDERGCHVNECLSRKLSGCSQDCEDLKIGFKCRCRPGFRLKDD-GRTCADL 2984
Query: 1018 NECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRG----YCVSNNADKM 1185
+EC+ C QLC N + C C+ + RG C + ++
Sbjct: 2985 DECSTTFPCSQLCINTHGSYKCLCV--------------EGYAPRGGDPHSCKAVTDEEP 3030
Query: 1186 KLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDD 1365
L A R L +LN + + K + +DFDY ++ I+WTD + +
Sbjct: 3031 FLIFANRYYLRKLNLDGSNYTLLKQGLNNAV-ALDFDYREQMIYWTDVTTQGSMIRRMHL 3089
Query: 1366 EGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTL 1545
G S ++ L L P LAVDW+ LY + G I+VS +G RTVL++ GL
Sbjct: 3090 NG--SNVQVLHRTGLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVSSGLRE 3147
Query: 1546 PLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWV 1716
P + +D G +++T + + MDG+ R +V+T +G+ VD +R+YW
Sbjct: 3148 PRALVVDVQNGYLYWTDWGDHSLIGRIGMDGSGRSIIVDTKITWPNGLTVDYVTERIYWA 3207
Query: 1717 DPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFGSDT 1896
D + D +E G++R +V +PH F L LF+ Y+YWTDW + + K
Sbjct: 3208 DAREDYIEFASLDGSNRHVVLS--QDIPHIFALTLFEDYVYWTDWETKSINRAHKTTGAN 3265
Query: 1897 KLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFG 2076
K L +T + PM + +H + QP C N C +C+LS G
Sbjct: 3266 KTLLISTLHR--PMDLHVFHALRQPDVPNHPC-------KVNNGGCSNLCLLSP-----G 3311
Query: 2077 VGYKCACPIGQKL-VNGKRCIDS 2142
G+KCACP L +G+ C+ +
Sbjct: 3312 GGHKCACPTNFYLGGDGRTCVSN 3334
Score = 315 bits (808), Expect = 2e-83
Identities = 222/745 (29%), Positives = 322/745 (42%), Gaps = 83/745 (11%)
Frame = +1
Query: 139 NTASSVCNENDFRCND-GKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWH 315
N C ++FRC D G+CI W P + D+ C+ Y +
Sbjct: 3489 NCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDGSD-----EPKEECDERTCEPYQFR 3543
Query: 316 SVS--CIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKY 489
+ C+ +CD DC D SDE+ C T S++ F CA+GR C KCDG +
Sbjct: 3544 CKNNRCVPGRWQCDYDNDCGDNSDEESC---TPRPCSESEFSCANGR-CIAGRWKCDGDH 3599
Query: 490 DCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTC--EFK 663
DC D SDEKD R C QF+C CI W CD DC DGSDE + C +
Sbjct: 3600 DCADGSDEKDCTPR----CDMDQFQC-KSGHCIPLRWRCDADADCMDGSDE-EACGTGVR 3653
Query: 664 KCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDE--DECGEYRCPPGK-WNCPGTGHCIDQ 834
C +EFQC N C+P ++CD DDCGDNSDE +EC + CPP + + C C+
Sbjct: 3654 TCPLDEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEECARFICPPNRPFRCKNDRVCLWI 3713
Query: 835 LKLCDGSKDCADGADEQQC----SQN---------LCPSLGC------------------ 921
+ CDG +C DG DE+ C +QN LC + C
Sbjct: 3714 GRQCDGVDNCGDGTDEEDCEPPTAQNPHCKDKKEFLCRNQRCLSSSLRCNMFDDCGDGSD 3773
Query: 922 ----------------------QAGCHPSPHGGECTCPSGYKLDDRFHRT-----CSDIN 1020
+A C + C C SG FH C DIN
Sbjct: 3774 EEDCSIDPKLTSCATNASMCGDEARCVRTEKAAYCACRSG------FHTVPGQPGCQDIN 3827
Query: 1021 ECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVA 1200
EC FG C QLC N + G CSC ++ + C + ++ L++A
Sbjct: 3828 ECLRFGTCSQLCNNTKGGHLCSC-------------ARNFMKTHNTCKAEGSEYQVLYIA 3874
Query: 1201 RREGLYRLNPKNPDEEVKKLASGE---FIYGIDFDYGDRKIFWTD----RLAHSAF---S 1350
+ L P +P ++ G+ I +D +++WT+ +++ + +
Sbjct: 3875 DDNEIRSLFPGHPHSAYEQTFQGDESVRIDAMDVHVKAGRVYWTNWHTGTISYRSLPPAA 3934
Query: 1351 ADVDDEGEISQIKK----LSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRT 1518
QI + L++ L PR +A+DW+ +Y +SG I+V+ GE R
Sbjct: 3935 PPTTSNRHRRQIDRGVTHLNISGLKMPRGIAIDWVAGNVYWTDSGRDVIEVAQMKGENRK 3994
Query: 1519 VLLADGLTLPLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVD 1689
L++ + P I +DPLRG M+++ N K+E AAMDGT R TLV + +G+ VD
Sbjct: 3995 TLISGMIDEPHAIVVDPLRGTMYWSDWGNHPKIETAAMDGTLRETLVQDNIQWPTGLAVD 4054
Query: 1690 ITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVI 1869
+R+YW D K+ + SI G D + A + HPF + +F+ Y+Y + V
Sbjct: 4055 YHNERLYWADAKLSVIGSIRLNGTDPIVAADSKRGLSHPFSIDVFEDYIYGVTYINNRVF 4114
Query: 1870 QVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCI 2049
++ KFG L + T + YH QP ++ NPC CE +C+
Sbjct: 4115 KIHKFGHSP--LINLTGGLSHASDVVLYHQHKQP----------EVTNPCDRKKCEWLCL 4162
Query: 2050 LSKDNGGFGVGYKCACPIGQKLVNG 2124
LS G C CP G++L NG
Sbjct: 4163 LSPS------GPVCTCPNGKRLDNG 4181
Score = 178 bits (451), Expect = 4e-42
Identities = 90/247 (36%), Positives = 125/247 (50%), Gaps = 1/247 (0%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAE 336
C F+C+ G C + C Q++C ++ CI
Sbjct: 3375 CRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCT----NTNRCIPG 3430
Query: 337 YQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEK 516
RC+ +C DG DE+DCP T + N F C+ ++C CD DC D SDE
Sbjct: 3431 IFRCNGQDNCGDGEDERDCPEVTC---APNQFQCSITKRCIPRVWVCDRDNDCVDGSDEP 3487
Query: 517 DSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEP-DTCEFKKCTANEFQCK 693
+C++ C +FRC D +CI W CDG DC DGSDEP + C+ + C +F+CK
Sbjct: 3488 ANCTQ--MTCGVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCK 3545
Query: 694 NKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADG 873
N RC P +++CDY +DCGDNSDE+ C C +++C G CI CDG DCADG
Sbjct: 3546 NNRCVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFSC-ANGRCIAGRWKCDGDHDCADG 3604
Query: 874 ADEQQCS 894
+DE+ C+
Sbjct: 3605 SDEKDCT 3611
Score = 143 bits (360), Expect = 1e-31
Identities = 89/293 (30%), Positives = 128/293 (43%), Gaps = 40/293 (13%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDE-KDCP----------ASTVDCSS 420
C + Q+ C + CI + +CD DC D SDE DCP ST C++
Sbjct: 3335 CTASQFVCK-----NDKCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQFQCSTGICTN 3389
Query: 421 --------------------------QNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDS 522
+ F C + +C +C+G+ +C D DE+D
Sbjct: 3390 PAFICDGDNDCQDNSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDC 3449
Query: 523 CSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNK- 699
C QF+C+ +CI + WVCD DC DGSDEP C C +EF+CK+
Sbjct: 3450 ---PEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDEFRCKDSG 3506
Query: 700 RCQPRKFRCDYYDDCGDNSDE--DECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADG 873
RC P +++CD DDCGD SDE +EC E C P ++ C C+ CD DC D
Sbjct: 3507 RCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCK-NNRCVPGRWQCDYDNDCGDN 3565
Query: 874 ADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAE 1032
+DE+ C+ C E +C +G + R+ C ++CA+
Sbjct: 3566 SDEESCTPRPCSE-------------SEFSCANGRCIAGRW--KCDGDHDCAD 3603
Score = 142 bits (359), Expect = 2e-31
Identities = 93/290 (32%), Positives = 124/290 (42%), Gaps = 45/290 (15%)
Frame = +1
Query: 148 SSVCNENDFRCNDGKCI--------------RTEWXXXXXXXXXXXXXXXXXPHPGCKSD 285
SS +++F C +G+CI +++ + C S+
Sbjct: 2523 SSCRAQDEFECANGECISFSLTCDGVSHCKDKSDEKPSYCNSRRCKKTFRQCNNGRCVSN 2582
Query: 286 QWQC----------DTYTWHSVSC------------IAEYQRCDNITDCADGSDEKDCPA 399
C D + +C I RC+ DC D SDE +C
Sbjct: 2583 MLWCNGVDDCGDGSDEIPCNKTACGVGEFRCRDGSCIGNSSRCNQFVDCEDASDEMNC-- 2640
Query: 400 STVDCSS------QNVFM--CADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQY 555
ST DCSS + V C C+ S CDG DC D SDE+D C
Sbjct: 2641 STTDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDERDCPGVKRPRCPLN 2700
Query: 556 QFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYY 735
F C +CI SW CD DC +G DE +F C+ +F+C+N RC +++ CD
Sbjct: 2701 YFAC-PSGRCIPMSWTCDKEDDCENGEDETHCNKF--CSEAQFECQNHRCISKQWLCDGS 2757
Query: 736 DDCGDNSDE-DECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADE 882
DDCGD SDE C C P ++CPGT C+ + LCDG KDC DGADE
Sbjct: 2758 DDCGDGSDEAAHCEGKTCGPSSFSCPGTHVCVPERWLCDGDKDCTDGADE 2807
Score = 132 bits (333), Expect = 2e-28
Identities = 84/242 (34%), Positives = 106/242 (43%), Gaps = 14/242 (5%)
Frame = +1
Query: 430 FMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCD 609
F CA+ R C KCDG DC D SDE + HT C +F+C + +CI W+CD
Sbjct: 860 FACANNR-CIQERWKCDGDNDCLDNSDEAPALCHQHT-CPSDRFKC-ENNRCIPNRWLCD 916
Query: 610 GSKDCADGSDEPD-TCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDED-ECGEYR 783
G DC + DE + TC + C N+F C + RC P + CD DDCGD SDE C
Sbjct: 917 GDNDCGNSEDESNATCSARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPT 976
Query: 784 CPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECT 963
C P G CI+ CD DC D +DE AGC S +
Sbjct: 977 CFPLTQFTCNNGRCININWRCDNDNDCGDNSDE--------------AGCSHSCSSTQFK 1022
Query: 964 CPSGYKLDDRFHRTCSDINECAEFGYCDQLCAN------------HRPGFTCSCLGDCFT 1107
C SG + + H TC N+C + Y D+ AN H F C G C
Sbjct: 1023 CNSGRCIPE--HWTCDGDNDCGD--YSDETHANCTNQATRPPGGCHSDEFQCRLDGLCIP 1078
Query: 1108 LQ 1113
L+
Sbjct: 1079 LR 1080
Score = 112 bits (280), Expect = 3e-22
Identities = 153/619 (24%), Positives = 230/619 (36%), Gaps = 29/619 (4%)
Frame = +1
Query: 7198 CQ-ITDNLRKSPCTQLCFATPGTQTPTCSCARGVLKGR-TC--EEPDTYIMFSDGDKIID 7365
CQ I + LR C+QLC T G CSCAR +K TC E + +++ D I
Sbjct: 3823 CQDINECLRFGTCSQLCNNTKGGHL--CSCARNFMKTHNTCKAEGSEYQVLYIADDNEIR 3880
Query: 7366 VAIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAENPRL 7545
++ E + DV V RVY+ G IS+ S+ A P
Sbjct: 3881 SLFPGHPHSAYEQTFQGDESVRIDAMDVHVKAGRVYWT-NWHTGT-ISYRSLPPAAPP-- 3936
Query: 7546 VFGASKQPHAKEIR------HISDMKL------DWLTQKIYFTTGRGGKVMAIDTAGEHL 7689
+ H ++I +IS +K+ DW+ +Y+T + GE+
Sbjct: 3937 ---TTSNRHRRQIDRGVTHLNISGLKMPRGIAIDWVAGNVYWTDSGRDVIEVAQMKGENR 3993
Query: 7690 STIASG--DWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESIS 7863
T+ SG D +A+ +DP G ++WSD G P+IE + + G R+ +V ++I
Sbjct: 3994 KTLISGMIDEPHAIVVDPLRGTMYWSDWGN-------HPKIETAAMDGTLRETLVQDNIQ 4046
Query: 7864 LPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGYRAKS----LDIWDRWLYMS 8031
P +AVD+ N+++YWAD I +G + V A R S +D+++ ++Y
Sbjct: 4047 WPTGLAVDYHNERLYWADAKLSVIGSIRLNGTDPIVAADSKRGLSHPFSIDVFEDYIYGV 4106
Query: 8032 DPLSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNG 8211
++N VF+I K S L N+ + SDV +Q + C D
Sbjct: 4107 TYINNRVFKIHKFGHSPLINLTGG---------LSHASDVVLYHQHKQPEVTNPC--DRK 4155
Query: 8212 GCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSEPAKECLP-PY 8388
C+ LC L+ S C+C + L D T CV S + P P
Sbjct: 4156 KCEWLCL-------LSPSGPVCTCPNGKRL------DNGT-CVPVPSPTPPPDAPRPGTC 4201
Query: 8389 NFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHI 8568
QC +G L A K C P Y + C +C +
Sbjct: 4202 TLQCFNGGSCFLNARRQPKCRC------QPRYTGDK--------CELDQCWEYCHNGGTC 4247
Query: 8569 DDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPGLP 8748
G CP+ + T G+C N ++ C Q + PG
Sbjct: 4248 AASPSGMPTCRCPTGFTGPKCTAQVCAGYCSN-------NSTCTVNQGNQPQCRCLPGFL 4300
Query: 8749 ID------CRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPS 8910
D C G C N C AD G C C +C+ RC
Sbjct: 4301 GDRCQYRQCSGF---CENFGTCQMAAD---GSRQCRCTVYFEGPRCEVNKCS----RCLQ 4350
Query: 8911 GRCIPETWQCDGDNDCSDG 8967
G C+ D +C+DG
Sbjct: 4351 GACVVNKQTGDVTCNCTDG 4369
Score = 108 bits (270), Expect = 4e-21
Identities = 88/282 (31%), Positives = 119/282 (41%), Gaps = 23/282 (8%)
Frame = +1
Query: 325 CIAEYQRCDNITDCADG---SDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDC 495
C+ +Q N + C G ++ C A C +Q+ F CA+G +C S CDG C
Sbjct: 2494 CLLTHQGHVNCS-CRGGRILQEDFTCRAVNSSCRAQDEFECANG-ECISFSLTCDGVSHC 2551
Query: 496 RDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTA 675
+D SDEK S N C + FR + +C+ C+G DC DGSDE C C
Sbjct: 2552 KDKSDEKPSYC-NSRRC-KKTFRQCNNGRCVSNMLWCNGVDDCGDGSDE-IPCNKTACGV 2608
Query: 676 NEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPG---------KWNCPGTGHCI 828
EF+C++ C RC+ + DC D SDE C C C T C
Sbjct: 2609 GEFRCRDGSCIGNSSRCNQFVDCEDASDEMNCSTTDCSSYFRLGVKGVLFQPCERTSLCY 2668
Query: 829 DQLKLCDGSKDCADGADEQQC---SQNLCP--SLGCQAG-CHPSPH--GGECTCPSGYKL 984
+CDG+ DC D +DE+ C + CP C +G C P E C +G
Sbjct: 2669 APSWVCDGANDCGDYSDERDCPGVKRPRCPLNYFACPSGRCIPMSWTCDKEDDCENG--- 2725
Query: 985 DDRFHRTCSDINECAEFGYCDQLCANHR---PGFTCSCLGDC 1101
+D H C+ A+F C NHR + C DC
Sbjct: 2726 EDETH--CNKFCSEAQFE-----CQNHRCISKQWLCDGSDDC 2760
Score = 106 bits (264), Expect = 2e-20
Identities = 59/172 (34%), Positives = 78/172 (45%)
Frame = +1
Query: 391 CPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCA 570
C + CS+ + G +C C + L + +C N TA QF C
Sbjct: 3295 CKVNNGGCSNLCLLSPGGGHKC-----ACPTNFY---LGGDGRTCVSNCTAS---QFVCK 3343
Query: 571 DKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGD 750
+ +CI W CD DC D SDEP C KC +FQC C F CD +DC D
Sbjct: 3344 ND-KCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQFQCSTGICTNPAFICDGDNDCQD 3402
Query: 751 NSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLC 906
NSDE C + C P ++ C T CI + C+G +C DG DE+ C + C
Sbjct: 3403 NSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTC 3454
Score = 67.4 bits (163), Expect = 1e-08
Identities = 43/129 (33%), Positives = 56/129 (43%), Gaps = 19/129 (14%)
Frame = +1
Query: 610 GSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKF------------RCDYYDDCGDN 753
GS+ CA D+ + C AN +CQP +F +CD +DC DN
Sbjct: 824 GSRQCACAEDQVLDTDGVTCLANPSYVPPPQCQPGEFACANNRCIQERWKCDGDNDCLDN 883
Query: 754 SDEDE--CGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQ--CSQNLCP--SL 915
SDE C ++ CP ++ C CI LCDG DC + DE CS CP
Sbjct: 884 SDEAPALCHQHTCPSDRFKCE-NNRCIPNRWLCDGDNDCGNSEDESNATCSARTCPPNQF 942
Query: 916 GCQAG-CHP 939
C +G C P
Sbjct: 943 SCASGRCIP 951
Score = 47.0 bits (110), Expect = 0.014
Identities = 31/102 (30%), Positives = 42/102 (40%), Gaps = 10/102 (9%)
Frame = +1
Query: 8746 PIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMN---QQCAQHYVRC-PSG 8913
P C + C + CI CDG DC D +DE C Q+C + C +
Sbjct: 25 PKTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEHSCLGTE 84
Query: 8914 RCIPETWQCDGDNDCSDGWD------ETHTNCTDTAGKKICV 9021
C+P + C+G DC DG D E NC+ + CV
Sbjct: 85 LCVPMSRLCNGIQDCMDGSDEGAHCRELRANCSRMGCQHHCV 126
Score = 46.2 bits (108), Expect = 0.023
Identities = 62/231 (26%), Positives = 87/231 (36%), Gaps = 29/231 (12%)
Frame = +1
Query: 9142 TCTDQEFH---CTSNAKLAQPKYECIPR----------AW-LCDGDVTCAGGEDESTELC 9279
TCT Q F+ C NA+ QPK C PR W C TCA C
Sbjct: 4200 TCTLQCFNGGSCFLNAR-RQPKCRCQPRYTGDKCELDQCWEYCHNGGTCAASPS-GMPTC 4257
Query: 9280 KTEKKECNKGEF--RCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFF--QCAN 9447
+ C G +C+ Q C C ++ C C C P F +C
Sbjct: 4258 R-----CPTGFTGPKCTAQVC---AGYCSNNSTCTVNQGNQPQCR---CLPGFLGDRCQY 4306
Query: 9448 HKCVPNSWKCDGNDDCE---DGSDEKDCPKNSASAQ-KASKCSNGQFQCTSGECIDDAKV 9615
+C S C+ C+ DGS + C + + +KCS +C G C+ + +
Sbjct: 4307 RQC---SGFCENFGTCQMAADGSRQCRCTVYFEGPRCEVNKCS----RCLQGACVVNKQT 4359
Query: 9616 CDRNFDCTD-RSDESSLCFIDECS------LAEKPLCEQKCMDMKIGYKCD 9747
D +CTD R S L ID CS + K + E +C G +C+
Sbjct: 4360 GDVTCNCTDGRVAPSCLTCIDHCSNGGSCTMNSKMMPECQCPPHMTGPRCE 4410
>gi|47219712|emb|CAG12634.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 3848
Score = 2006 bits (5197), Expect = 0.0
Identities = 1327/4129 (32%), Positives = 1929/4129 (46%), Gaps = 171/4129 (4%)
Frame = +1
Query: 661 KKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLK 840
+ C +++F C+ +C P +RCD+ DC DNSDE+ C PP G C + +
Sbjct: 25 RTCGSDQFTCQEGQCVPASYRCDHVKDCLDNSDENNCNY---PPCTERTCANGACYNNSQ 81
Query: 841 LCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDIN 1020
C+G +DC DG+DE CS C +L C+ CHPSP GG C CP G+ + + R+C D +
Sbjct: 82 HCNGLQDCRDGSDEFNCSLQRCATLSCEYMCHPSPQGGACYCPDGFTVAND-SRSCVDYD 140
Query: 1021 ECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVA 1200
+C +G CD LC + CSC D + L+ H C +N + + +
Sbjct: 141 DCQIWGICDHLCEDRPGSHQCSC-ADGYFLEQGH-----------ICKANVSGGLPQLIF 188
Query: 1201 RREGLYRLNPKNPDEEVKKLASGE---FIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEG 1371
G + + V+ L + + G+ + + +FW+D F+A +
Sbjct: 189 TNGGDVMMADIH-GRFVRTLVPSQGRGYAVGVAYHWHSSTVFWSDTNTQKQFTASRTLQW 247
Query: 1372 EISQIKKLSLKS-------------------LVYPRCLAVD-WITNTLYIIESGSRRIDV 1491
S + S + L R L V W G I V
Sbjct: 248 TGSTLNSTSWRPWWNASMCVISVGRTASHWWLKICRVLTVSHWTRQWGAFTFCGFTNITV 307
Query: 1492 SS--YDGERRTVLLADGLTL--PLDIALDPLRGEMFFTN------QLKLEAAAMDGTNRR 1641
++ + RR +LL LTL P + L + MFFT+ Q+KLE A MDG+NR
Sbjct: 308 NTQKHSWNRRCILLKSFLTLEKPRILTLLCVCSYMFFTDMGTATEQVKLERAFMDGSNRV 367
Query: 1642 TLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLAL 1821
LV + I VDI KRVYW D D +E++ Y G DR+IV G P+PFG+A
Sbjct: 368 ELVKKRLGIPAAITVDIVTKRVYWTDIHFDTVETVTYSGLDRKIVLNGGTKAPYPFGIAT 427
Query: 1822 FDQYLYWTDWTRLGVIQVEKFGSDT-KLLWSNTENNVFPMGISAYHPMAQPGPGQSECLA 1998
F+ +L++TDWT++GV++ +F + +L++ T P + H + QP
Sbjct: 428 FENHLFFTDWTKMGVMKANRFKENNPELIYRTTRR---PGHVVVSHSVLQP--------- 475
Query: 1999 MKIENPCT--NADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGKR-CIDSIDYLLFSSN 2169
+ NPC N C+ +C+LS G+G++C C G L + R C D+LL +S+
Sbjct: 476 -VVMNPCGRHNGGCQHICVLSHRTDNDGLGFRCKCRHGYDLHSDHRTCFKVKDFLLIASS 534
Query: 2170 KIVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRP 2349
VRGI +N + LP+S ++ G VE D S FY D +Y+
Sbjct: 535 LAVRGI--PLNLSLQEDLTLPLSGLATSFSGS--AVEFDGIKESIFYNDRSRGLVYKSNL 590
Query: 2350 DGEGAAPVLVTHNDGLF-SMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQL 2526
+G +L + G+ +M++DW S L++ + S+ K+ + RR +
Sbjct: 591 NGT-VQEILTGYRVGVIDAMAYDWTSNILFWTTSTYQSVVAFKVTDKS--------RRDI 641
Query: 2527 ITELRDPVSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAE 2706
+T LR P + VHP G LF+++ RPA I R DG N + NTTLG P +A+D+
Sbjct: 642 VTGLRYPKGIAVHPSAGYLFWSDWYRPAVIMRAFTDGSNAIPLVNTTLGWPYGLALDYIT 701
Query: 2707 NRLCWGDTLLKTISCMDFDGKNVVKLDIDNPI--PVAITIMNEYIYYVHQRPYSIRRVHK 2880
+RL W D+ L + +D G + I P ++T+ +Y+Y R SI + K
Sbjct: 702 DRLYWVDSQLDQVGHIDIQGSDRQTFTNIGEITQPYSLTVYTDYLYVADTRTRSIYEMRK 761
Query: 2881 KNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPN 3060
++GGGS +VR R I ++ + R QC+ CF P S
Sbjct: 762 RDGGGSVVVR------RGITAIMNIKAYTPELHSCIRCTKPPNGQCSHFCFPVPPFSR-- 813
Query: 3061 ELEAKCACRQGFMINKENNHSCQKDPA-EKIEQLCSSNSTQFQCKNGRCIPKEWKCDGEN 3237
KC C G + ++N C KD + + C N+ F+C GRC P ++CDG
Sbjct: 814 ----KCGCPYGMKL-QDNKRDCIKDDSVPPPDNNCGDNA--FECDEGRCRPNSYRCDGII 866
Query: 3238 DCLDESDEIDEKGDKCFHE-TECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYC 3414
DC+D+SDE + C C+ C N K CI + C
Sbjct: 867 DCVDKSDEAN-----CTDTGATCSPLAFTCDN-KHCILSGWRCDGLDDCGDGSDEM--NC 918
Query: 3415 KDGQKPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNATCAANQFSCANGR 3594
C+A F CDN+RCI + + E TC N F C + R
Sbjct: 919 PTKTPTTCSADYFTCDNYRCISKSFLCDGDNDCGDGSDEHNCNSTITTCPPNYFLCPDHR 978
Query: 3595 CIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQCVPLRNHXXXXXXXXXXX 3774
CI ++CDGD DC DG+DE + C C++ +F CA+G QCV
Sbjct: 979 CIYNSYVCDGDQDCLDGSDE--KDCE-FACASYEFACASGDQCVSSSYRCDGVFDCRDHS 1035
Query: 3775 XXXXXAVTAES-CTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQ 3951
C D+F+C + G CIP W+ SDE C C +
Sbjct: 1036 DEQDCPTRGPGLCHDDEFQCQNDGFCIPGVWECDGHSDCEDGSDEHN-SCPPVT-CRPNY 1093
Query: 3952 FKCGNGRCILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLH 4131
++C N CI +W CDG+NDC D SDE + C T +CP C DQ CI L
Sbjct: 1094 YQCQNKLCIPTSWQCDGDNDCLDMSDEQN---CPTP--PFRCPSGQWQCPTDQ-LCIDLD 1147
Query: 4132 QLCDGKTHCPGGTDEGGRCARDLCSADRAGCSFKCHNSPNGPICSCPFGEQLVNKTK-CE 4308
++CDG++ CP G DE C +D C + GCS C P G CSCP G QL+N +K CE
Sbjct: 1148 KVCDGQSDCPNGADESPICNQDDCILNNGGCSDICTQGPFGAQCSCPSGFQLLNDSKTCE 1207
Query: 4309 PENECLDSSSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYY 4488
NECL CSQ C +E+ F C C EGY L+ D RTCK D +D + ++ R++I
Sbjct: 1208 DINECLIPGFCSQECYNERGSFRCYCSEGYLLEPDGRTCKAIDT-QDAVLLIAKRSQI-- 1264
Query: 4489 SDHKLDNWHT-----FGAIVENA--IALAWDSLTDRIYWSDIREKKILSANRNGTNATVF 4647
+ NW +V + + + +D +T RIYW+D +KKI S+ +NGT+
Sbjct: 1265 ----IANWVNKKPPQMKPVVSGSSIVTVDFDRVTSRIYWADASQKKIWSSYQNGTDKREV 1320
Query: 4648 IADGLDITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPR 4827
+ GL + E IA+DWVGRNLYW DS + IEV+ L D + R +L+ +NV+ PRG+ +DPR
Sbjct: 1321 FSTGLMVPESIAVDWVGRNLYWTDSVMENIEVSTL-DGRFRKVLLSKNVTSPRGLVLDPR 1379
Query: 4828 K--GVMFWTDWGQNPCIERASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFI 5001
+MFW+DWGQNP IERA MDGT RQ+IV TK+YWPN +ALDYTT R+YFAD+ L +I
Sbjct: 1380 NHTNLMFWSDWGQNPRIERAFMDGTVRQVIVSTKLYWPNGLALDYTTHRIYFADAYLKYI 1439
Query: 5002 DFVNYDGSGRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSH 5181
D+ +YDGS R QV+AS+ +QHPH + IFE+ +Y+S+R K+ K+ + S
Sbjct: 1440 DYCSYDGSNRHQVMASNMVLQHPHGMTIFENYVYWSERYTSKVMRTNKFHGSNFTTVMSS 1499
Query: 5182 TFSKALGVVAVHPVLQPVIKNNPCSTNPCSHLCLLN--NKNTFTCKCPMGEKLDASGKKC 5355
+ + +G+V HP+ QP + + C+ LCLL+ +TC C G KLDA + C
Sbjct: 1500 VY-QPMGIVMDHPIKQPTV------NSLCTQLCLLSGLRPRYYTCHCQSGWKLDADKRTC 1552
Query: 5356 IDDAKPFLVIIQKTNVFGIEMNSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILE 5535
I D FL++++++ +FGI + + P M P+SG+ D +D E ++ ++
Sbjct: 1553 IKDESTFLMVVRESVIFGIPL----DPNDPSNNAMTPVSGISQGQDIDFDDQEELVYWVQ 1608
Query: 5536 HTNHAKTLAQITTDSAIYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQT 5715
+T +I++ +G N+++ +A+ L FDW R + N ++
Sbjct: 1609 NT------------GSIWKVKTSGTNRSEFAPAAIMGSPSGLAFDWITRMMFYTNPTGKS 1656
Query: 5716 IEIIRTQGKQ-YRSVILSNDQSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGL 5892
IE+IR G Q YR ++++ +G +FW D+G KV A +
Sbjct: 1657 IEVIRVDGSQHYRKTLITSTGKPEETGQPIGIAVDPARGKLFWTDKGSENVPPKVGSADM 1716
Query: 5893 DGSNPLVIASNDLAELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPN 6072
DG N + + +LA + + D + +++Y+ + +G I T DG + V+S G P
Sbjct: 1717 DGGNLKNLYTENLANIGVLTADISASKLYWGVSGSGVIECGTMDGLTKVTVVS-GLSHPW 1775
Query: 6073 GLAFYGDRLFYADSAFDSIEVATINGDSQPPQWTHFKKDVENLANIKALQPRASSSG--H 6246
GL + + L+Y D ++ IE N + + + L +K + R S+G +
Sbjct: 1776 GLTVHQNYLYYTDLDYEVIERVDKNSGA---NMVVMRSGMSGLRALK-VHTRDDSAGTDN 1831
Query: 6247 PCHINNGNCDHICIPLMFAQRTCTCANGYV--KDGQTSCKLFDESFVIVATKTKVIGYPI 6420
C NNG C +C+P Q+TC C G++ DG T C+ + ES+ +V+T + G+ I
Sbjct: 1832 ACSSNNGGCAQLCLPKPDHQKTCACTTGFIMSPDG-TRCEQY-ESYAVVSTDKYIRGFHI 1889
Query: 6421 DETQSKGVAMEPIGGLSIT---GVDYDYESKTIYVAEASGIN--KGITAYTIGESSPRAV 6585
+ + AM PI G S + +D +S +Y + S + +GI V
Sbjct: 1890 N-SSDHSEAMVPISGSSYSVKGTMDLHIQSGFVYYIDNSTYSSYRGIYRTKTSGGFTTRV 1948
Query: 6586 IRDSIGSLTIKSLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAV 6765
I IG L I+ LA+DWI N+YF N T +EV ++ T R ILL + + P +AV
Sbjct: 1949 IGSGIGKLGIQGLAVDWITGNLYFTNAFESETLLEVHVINTTNRMILLKSSHDQPRDLAV 2008
Query: 6766 DPVSRYLYWADQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDG 6945
P RYL+W D GQ P I+R+ LDG+ R V+ S +A P L VD + +YW+D +D
Sbjct: 2009 SPKLRYLFWTDGGQTPKIERALLDGTNRTVLASESLASPRGLTVDYTNDFLYWTDDVLDM 2068
Query: 6946 IYRVRSTGGTPELVR--SDIASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPT 7119
I R+ S G +++R S S GVA+ G NM W D +L KLF+A SK N +S P
Sbjct: 2069 ISRMASDGSQRQIIRYGSRYPSPVGVAILGNNMLWVDKKLGKLFQA-SKGNTSS--AQPE 2125
Query: 7120 TVAASLKDIGDVAVFSSNNQPRAS-----SPCQITDNLRKSPCTQLCFATPGTQTPTCSC 7284
+ +L + D+A+F + QP AS +PC C QLCFA P P C C
Sbjct: 2126 VIRDNLDGLMDIAIFDVHVQPTASHQVAFNPCY----EHNGGCQQLCFAIPDQDHPKCGC 2181
Query: 7285 ARGVL--KGRTCEEP-DTYIMFSDGDKIIDVAIEPDVKASRPLKDPFPEIS-NLQTFDVD 7452
A G L G TC D +++F+ + + ++P A + P ++S ++ D D
Sbjct: 2182 AHGSLLSNGVTCGYGLDEFLVFTTDYTLNSLRLDP---ADHSVPYPTVDLSYGVKALDYD 2238
Query: 7453 VNLRRVYFVVESPVGVN-ISWFSMNNAENPRLVFGASKQPHAKEIRHISDMKLDWLTQKI 7629
+R++F +G + I + S + +P + +S
Sbjct: 2239 FKEKRIFFTQYMGIGYSKIGYISTTSPTSPPTIINSS----------------------- 2275
Query: 7630 YFTTGRGGKVMAIDTAGEHLSTIASGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIE 7809
TT G L+ID +L+W+D+ +IE
Sbjct: 2276 -LTTPNG------------------------LSIDYEERMLYWADASL--------DKIE 2302
Query: 7810 RSNLAGGSRKVIVSESISLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGYR 7989
R+ L G +R +I+ + P A+ V Q I+W D
Sbjct: 2303 RATLTGENRHIIL-HGVVYPYAMTV--FQQDIFWTD------------------------ 2335
Query: 7990 AKSLDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVSDRRI-PGALRVFASESDVRTRNQ 8166
W VFR K+ GSG + D + P + V+A ++ +
Sbjct: 2336 ------W---------TERAVFRARKDGGSGFAVLAQDLQYRPNDIHVYAG-----SKQE 2375
Query: 8167 VCNALTSQLCKTDNGGCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLR 8346
+C S C+ NGGC +C G + + QC + ++ L + GKD C+
Sbjct: 2376 MC----SSSCQQFNGGCSHICV-----SGPSGPECQCPHDGSWYLAND-GKD----CI-- 2419
Query: 8347 GSNSEPAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCT 8526
+ K C F C +G CI + CD DC D SDE C +C +C
Sbjct: 2420 ---QDTGKRCQAD-QFTCLNGHCISVSWKCDGYNDCQDNSDELERVCAFHTCSATEFVCD 2475
Query: 8527 NRRCIDSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDE 8706
N RC+ + C++ +DC D SDE CP F C NG CI+ +CDGHNDC D
Sbjct: 2476 NGRCVPLSYVCDYTNDCRDNSDERGCPFPTCNPTTEFTCDNGRCISADFICDGHNDCRDN 2535
Query: 8707 QVSDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFC------ 8868
SDE CP C V+C +TNICI P +LCDGY++CGD +DEN LFC
Sbjct: 2536 ATSDE--INCPDR--TCPDGLVKCDHTNICIYPGNLCDGYNNCGDNSDENPLFCGKINNA 2591
Query: 8869 -------------------------MNQQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWD 8973
+ C+ + RC SG+CIP +W CDG DC DG D
Sbjct: 2592 LLSFIRIDMLNILCFTDKYLNLCSSETRTCSMNEFRCDSGKCIPNSWVCDGIRDCQDGTD 2651
Query: 8974 ETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTD 9153
E + GK F C N CI + + CG RTC+
Sbjct: 2652 EPL-----SCGKSCAF--VQFTCTNGNCIPQFMLCDGNNDCWDNSDEAVELDCGERTCSS 2704
Query: 9154 QEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECNKGEFRCSNQH 9333
+F C + PK C+P +++CDG+ CA D EL + C+ EF CSN
Sbjct: 2705 VQFTCPTWIP-GFPK--CLPISYVCDGERDCANAAD---ELRNCPNRTCHLDEFSCSNGL 2758
Query: 9334 CIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCANHKCVPNSWKCDGNDDCEDGSDE 9513
CI + CD NDC DGSDE CTY +C + F C N C+ +++ CDG DC DGSDE
Sbjct: 2759 CILLPFHCDRVNDCGDGSDE-LGCTYDTCSSNQFTCTNGACISSAFTCDGMSDCLDGSDE 2817
Query: 9514 KDCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAE 9693
+D S C+ Q+ CTSG+CID +VCD DC D SDE C I+EC+
Sbjct: 2818 ED----SLCVSPQPTCAPQQYMCTSGQCIDTNRVCDGQKDCPDNSDEKG-CGINECTNPS 2872
Query: 9694 KPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCG 9873
C Q C D GY C C G+ + + D K+C ++NEC + CSQ C++ +GSY C
Sbjct: 2873 VHKCAQLCTDTLTGYYCSCQPGYRL-MPDGKACEDINECSSTPAVCSQICENVVGSYYCK 2931
Query: 9874 CVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYELAAQGFDNVVSLDIDL 10053
C GY +D +C R P+ L +N++YIR ++ DG+ + QG N V+LD D
Sbjct: 2932 CAPGYIREADGRTC-RQNSGIAPYLLYSNRYYIRNLTTDGSHLSIVLQGLTNAVALDFDH 2990
Query: 10054 TEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQE 10233
+EK+ Y +D G ++ R+ D D VL ++V EG+A+DWVGRKLY +
Sbjct: 2991 SEKRLYWLDAGTRKIERMRFDGTD------REVLANDVMAAEGLALDWVGRKLYWTDSYY 3044
Query: 10234 RSIRVCELDGRFCKTLIRDR---------IQQPKAIVVHPGKGYLFFTEWSLQPYIGRIA 10386
S+ V EL+G + + L+ I +P+A+ V+P G++++T+W+ YIGR
Sbjct: 3045 GSVHVMELNGLYQRKLLSGHFKEGNSTYIISRPRAVAVNPKYGWVYWTDWADMAYIGRAG 3104
Query: 10387 LDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHIPAQ 10566
+DG + + L WP+A+ IDY ++R+F+ D+HLN + F D DG R
Sbjct: 3105 MDGR-----NVSAIITTKLEWPSALTIDYTTNRIFFADSHLNFLDFADMDGQNRHRAVGG 3159
Query: 10567 RTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDLRIVHPMRQPAY 10746
HV ++ +F+D++YW DWN V + K+TG+ T++ P D+ + HP RQP
Sbjct: 3160 TLPHVFAVSLFEDWVYWTDWNTHTVEKAHKYTGEMRTVMGNNTHRPYDIHVYHPYRQPRS 3219
Query: 10747 PNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLS--DQKTCEPNCTERQFACGGDDAK 10920
NPC ++ CSHLCLIG GG +C CPD F+ L+ + C +C+ QF C GD+ K
Sbjct: 3220 ENPCSSHHLTCSHLCLIGPGGQQASCECPDHFIGLAVGFKIQCVADCSSTQFRC-GDNEK 3278
Query: 10921 CIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXX 11100
CIP W CDG+ DC DGSDEP C R CPVG+FQC + NCT I
Sbjct: 3279 CIPIWWECDGQSDCGDGSDEP--QTCPPRYCPVGQFQCQDRNCTHSGFI----------- 3325
Query: 11101 XEQNCDKACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEADTLCMSAERNCTAEEFRC 11280
CD D C SDE LC ++ C +F+C
Sbjct: 3326 ----CDGHAD-----CP-------------------DHSDEDAALC--SDHRCQENQFQC 3355
Query: 11281 NNNKCIAKAWRXXXXXXXXXXXXETPE-CAQIECKKGWTRCSSSYRCIPNWAFCNGQDDC 11457
N KCI +W E PE C+Q C G +C++ RC+P+ C+ Q+DC
Sbjct: 3356 KNKKCIPVSWHCDGVKDCSDNSDEDPETCSQKTCAPGQFQCANG-RCLPSSYVCDFQNDC 3414
Query: 11458 RDNSDEDKQRCP---------------------------------------------TCD 11502
DNSDE + C CD
Sbjct: 3415 GDNSDEPLETCSKSRHVSVTQTWSLQKRKEITFFNIFLIMMLTFVMHFLSCPVGPDYKCD 3474
Query: 11503 DVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSE-SEFRCNDGKCIPG 11679
+ EF C T+ +CIP+ CD NDC DNSDE C T C +FRC++ +CIP
Sbjct: 3475 ET-EFSCKTNYRCIPQWARCDGTNDCLDNSDE--EGCEDVT--CDPLGDFRCDNHRCIPI 3529
Query: 11680 SKVCDGTIQCSDGLDESQCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCED 11859
CDG C DG DE C R C +CD CI CD DC + +DE C
Sbjct: 3530 RWQCDGNNDCGDGSDERNCQPRPCSESEFRCDSQQCIPATWVCDHMNDCGDNSDERDC-- 3587
Query: 11860 VSRRTCS-PFEFECANSVCIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPL--RFRCAH 12030
+ TC P +F CAN CI + SDET CR P F+C++
Sbjct: 3588 AATITCEMPSKFRCANGYCIFAGLLCNQKDDCGDGSDETEDLCREPTLPPCTLDEFKCSN 3647
Query: 12031 SRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDR 12210
C+ + +C+ ++CG D +D
Sbjct: 3648 GH-CVPLPYVCDHNDNCG--DLTD------------------------------------ 3668
Query: 12211 KDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKHICTDVR-DGFYCHCRDGFRPDPQSPKE 12387
E+GC+ G +CE C+H+CT++ GF C C+ G++ +P S
Sbjct: 3669 ---------ELGCN-FGNDRNCE----EKLCQHVCTNLNGTGFICSCKPGYKVNPDSTTT 3714
Query: 12388 CIDIDECAGNNTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAK 12534
C+DIDEC TC Q C NTKGSY C C Y VG GK C A+
Sbjct: 3715 CLDIDECQIYGTCPQFCKNTKGSYDCECAPGYRK---VGD--GKMCEAE 3758
Score = 436 bits (1120), Expect = e-119
Identities = 314/1064 (29%), Positives = 486/1064 (45%), Gaps = 70/1064 (6%)
Frame = +1
Query: 130 ASVNTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPG---CKSDQWQCD 300
A+ + C+ F C++ CI + W P C +D + CD
Sbjct: 875 ANCTDTGATCSPLAFTCDNKHCILSGWRCDGLDDCGDGSDEMNCPTKTPTTCSADYFTCD 934
Query: 301 TYTWHSVS------------------------------------CIAEYQRCDNITDCAD 372
Y S S CI CD DC D
Sbjct: 935 NYRCISKSFLCDGDNDCGDGSDEHNCNSTITTCPPNYFLCPDHRCIYNSYVCDGDQDCLD 994
Query: 373 GSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQ 552
GSDEKDC + C+S F CA G QC S +CDG +DCRD SDE+D +R C
Sbjct: 995 GSDEKDCEFA---CASYE-FACASGDQCVSSSYRCDGVFDCRDHSDEQDCPTRGPGLCHD 1050
Query: 553 YQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDY 732
+F+C + CI W CDG DC DGSDE ++C C N +QC+NK C P ++CD
Sbjct: 1051 DEFQCQNDGFCIPGVWECDGHSDCEDGSDEHNSCPPVTCRPNYYQCQNKLCIPTSWQCDG 1110
Query: 733 YDDCGDNSDEDEC--GEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQ-CSQNL 903
+DC D SDE C +RCP G+W CP CID K+CDG DC +GADE C+Q+
Sbjct: 1111 DNDCLDMSDEQNCPTPPFRCPSGQWQCPTDQLCIDLDKVCDGQSDCPNGADESPICNQDD 1170
Query: 904 C--PSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGF 1077
C + GC C P G +C+CPSG++L + +TC DINEC G+C Q C N R F
Sbjct: 1171 CILNNGGCSDICTQGPFGAQCSCPSGFQLLND-SKTCEDINECLIPGFCSQECYNERGSF 1229
Query: 1078 TCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYR--LNPKNPDEEV 1251
C C + + L+ D T C + + L +A+R + +N K P ++
Sbjct: 1230 RCYC-SEGYLLE------PDGRT----CKAIDTQDAVLLIAKRSQIIANWVNKKPP--QM 1276
Query: 1252 KKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLA 1431
K + SG I +DFD +I+W D +S+ + + +++ L+ P +A
Sbjct: 1277 KPVVSGSSIVTVDFDRVTSRIYWADASQKKIWSSYQNGTDK----REVFSTGLMVPESIA 1332
Query: 1432 VDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLR--GEMFFTN--- 1596
VDW+ LY +S I+VS+ DG R VLL+ +T P + LDP MF+++
Sbjct: 1333 VDWVGRNLYWTDSVMENIEVSTLDGRFRKVLLSKNVTSPRGLVLDPRNHTNLMFWSDWGQ 1392
Query: 1597 QLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIV 1776
++E A MDGT R+ +V+T + +G+ +D T R+Y+ D + ++ Y G++R V
Sbjct: 1393 NPRIERAFMDGTVRQVIVSTKLYWPNGLALDYTTHRIYFADAYLKYIDYCSYDGSNRHQV 1452
Query: 1777 AQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKF-GSDTKLLWSNTENNVFPMGISAY 1953
V+ HP G+ +F+ Y+YW++ V++ KF GS+ + S+ PMGI
Sbjct: 1453 MASNMVLQHPHGMTIFENYVYWSERYTSKVMRTNKFHGSNFTTVMSSVYQ---PMGIVMD 1509
Query: 1954 HPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGKR- 2130
HP I+ P N+ C +C+LS + Y C C G KL KR
Sbjct: 1510 HP---------------IKQPTVNSLCTQLCLLSGLRPRY---YTCHCQSGWKLDADKRT 1551
Query: 2131 CI-DSIDYLLFSSNKIVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFF 2307
CI D +L+ ++ GI + N+ + A+ P+S ISQ + +++ D +
Sbjct: 1552 CIKDESTFLMVVRESVIFGIPLDPNDPS-NNAMTPVSGISQGQ-----DIDFDDQEELVY 1605
Query: 2308 YADIMDNTIYRIRPDGEGA---APVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKI 2478
+ +I++++ G AP + + ++FDWI++ ++Y + S+EV+++
Sbjct: 1606 WVQ-NTGSIWKVKTSGTNRSEFAPAAIMGSPS--GLAFDWITRMMFYTNPTGKSIEVIRV 1662
Query: 2479 GETGLVHPDELVRRQLIT------ELRDPVSVVVHPWKGLLFYAEAMR---PAAIYRCHI 2631
G H R+ LIT E P+ + V P +G LF+ + P + +
Sbjct: 1663 --DGSQH----YRKTLITSTGKPEETGQPIGIAVDPARGKLFWTDKGSENVPPKVGSADM 1716
Query: 2632 DGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVKLDIDNPIPVA 2811
DG N + + L + D + ++L WG + I C DG V + P
Sbjct: 1717 DGGNLKNLYTENLANIGVLTADISASKLYWGVSGSGVIECGTMDGLTKVTVVSGLSHPWG 1776
Query: 2812 ITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDS- 2988
+T+ Y+YY I RV K +G ++R + L+A + DDS
Sbjct: 1777 LTVHQNYLYYTDLDYEVIERVDKNSGANMVVMRS------GMSGLRALKVHTR---DDSA 1827
Query: 2989 -REHPCRASQ--CTQLCFATPSESHPNELEAKCACRQGFMINKE 3111
++ C ++ C QLC P + CAC GF+++ +
Sbjct: 1828 GTDNACSSNNGGCAQLCLPKPDH------QKTCACTTGFIMSPD 1865
Score = 341 bits (874), Expect = 4e-91
Identities = 308/1137 (27%), Positives = 448/1137 (39%), Gaps = 76/1137 (6%)
Frame = +1
Query: 10450 PNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWN 10629
PN ++IDY L+W DA L++I G R HI + +M VF ++W DW
Sbjct: 2279 PNGLSIDYEERMLYWADASLDKIERATLTGENR-HIILHGVVYPYAMTVFQQDIFWTDWT 2337
Query: 10630 LREVLRCDKWTGKNETILKKTVQL-PNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAG 10806
R V R K G +L + +Q PND+ + +Q + C NGGCSH+C+ +G
Sbjct: 2338 ERAVFRARKDGGSGFAVLAQDLQYRPNDIHVYAGSKQEMCSSSCQQFNGGCSHICV--SG 2395
Query: 10807 GNGYTCSCPDQFVLLSDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPG 10986
+G P C C D + WY DG D
Sbjct: 2396 PSG-------------------PECQ-----CPHDGS------WYL-----ANDGKDCIQ 2420
Query: 10987 ESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXXEQNCDK--------ACDPWMF 11142
++ G+R C +F C N +C I + N D+ C F
Sbjct: 2421 DT--GKR-CQADQFTCLNGHC-----ISVSWKCDGYNDCQDNSDELERVCAFHTCSATEF 2472
Query: 11143 KCAATGRCIPRRFTXXXXXXXXXRSDEADTLCMSAERNCTAEEFRCNNNKCIAKAWRXXX 11322
C GRC+P + SDE C N T E F C+N +CI+ +
Sbjct: 2473 VCD-NGRCVPLSYVCDYTNDCRDNSDERG--CPFPTCNPTTE-FTCDNGRCISADFICDG 2528
Query: 11323 XXX-XXXXXXETPECAQIECKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCP-- 11493
+ C C G +C + CI C+G ++C DNSDE+ C
Sbjct: 2529 HNDCRDNATSDEINCPDRTCPDGLVKCDHTNICIYPGNLCDGYNNCGDNSDENPLFCGKI 2588
Query: 11494 -------------------------------TCDDVGEFRCATSGKCIPRRWMCDTENDC 11580
TC + EFRC SGKCIP W+CD DC
Sbjct: 2589 NNALLSFIRIDMLNILCFTDKYLNLCSSETRTCS-MNEFRC-DSGKCIPNSWVCDGIRDC 2646
Query: 11581 GDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDES---QCTLRRC 11751
D +DE SCG + C+ +F C +G CIP +CDG C D DE+ C R C
Sbjct: 2647 QDGTDE-PLSCG---KSCAFVQFTCTNGNCIPQFMLCDGNNDCWDNSDEAVELDCGERTC 2702
Query: 11752 LPGHRQCDDGT-----CIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFECANSVCI 11916
C C+ CD ++DC NAADEL + RTC EF C+N +CI
Sbjct: 2703 SSVQFTCPTWIPGFPKCLPISYVCDGERDCANAADELR--NCPNRTCHLDEFSCSNGLCI 2760
Query: 11917 PRKFMXXXXXXXXXXSDE---TSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGP 12087
F SDE T C S Q F C + C++ C+G +DC
Sbjct: 2761 LLPFHCDRVNDCGDGSDELGCTYDTCSSNQ------FTCTNGA-CISSAFTCDGMSDC-- 2811
Query: 12088 NDFSDEHLSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGK 12267
D SDE S+C S C+ Q+ C +G+C++ CD + DC D SDE GC G
Sbjct: 2812 LDGSDEEDSLC--VSPQPTCAPQQYMCTSGQCIDTNRVCDGQKDCPDNSDEKGC----GI 2865
Query: 12268 TSCEAFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGN-NTCTQLCLN 12444
C + C +CTD G+YC C+ G+R P K C DI+EC+ C+Q+C N
Sbjct: 2866 NECTNPSVHK-CAQLCTDTLTGYYCSCQPGYRLMPDG-KACEDINECSSTPAVCSQICEN 2923
Query: 12445 TKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQ-LSLHGSGTNRHXX 12621
GSY C+C Y + G+ CR A ++ ++ ++ L+ GS H
Sbjct: 2924 VVGSYYCKCAPGY-----IREADGRTCRQNSGIAPYLLYSNRYYIRNLTTDGS----HLS 2974
Query: 12622 XXXXXXXXXXXXXXXXPRKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVP 12801
K L YW+D R I R +G +V A +
Sbjct: 2975 IVLQGLTNAVALDFDHSEKRL-YWLDAGTRKIER-------MRFDGTDREV-LANDVMAA 3025
Query: 12802 TAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVA 12981
+A+D+ L+ + G + V +G Y +K+++
Sbjct: 3026 EGLALDWVGRKLYWT-----------------------DSYYGSVHVMELNGLYQRKLLS 3062
Query: 12982 GH---------LQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPT 13134
GH + +P A+ P G + ++D A I A MDG + I+ + P+
Sbjct: 3063 GHFKEGNSTYIISRPRAVAVNPKYGWVYWTDWADMAYIGRAGMDGRNVSAIITTKLEWPS 3122
Query: 13135 SMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDR--HIPYAVDVFENHIYWLSRE 13308
++ ID NRI++ D +D ++DG R V H+ +AV +FE+ +YW
Sbjct: 3123 ALTIDY-TTNRIFFADSHLNFLDFADMDGQNRHRAVGGTLPHV-FAVSLFEDWVYWTDWN 3180
Query: 13309 SKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPST 13488
+ T+ K+ +V+ ++ + + V Y + CSHLC+ P
Sbjct: 3181 THTVEKAHKYTGEMRTVMGNNTHRPYDIHVYHPYRQPRSENPCSSHHLTCSHLCLIGPGG 3240
Query: 13489 GFA-CLCPD---GIVPQLDGSCATQHVEALTMPKQCKCTNGGKC-----RLDGSCEC 13632
A C CPD G+ C A Q +C + KC DG +C
Sbjct: 3241 QQASCECPDHFIGLAVGFKIQCV-----ADCSSTQFRCGDNEKCIPIWWECDGQSDC 3292
Score = 326 bits (835), Expect = 1e-86
Identities = 249/980 (25%), Positives = 407/980 (41%), Gaps = 64/980 (6%)
Frame = +1
Query: 7198 CQITDNLRKSP--CTQLCFATPGTQTPTCSCARGVLK---GRTCEEPD---TYIMFSDGD 7353
C+ + +P C+Q+C G+ C CA G ++ GRTC + Y+++S+
Sbjct: 2904 CEDINECSSTPAVCSQICENVVGSYY--CKCAPGYIREADGRTCRQNSGIAPYLLYSNRY 2961
Query: 7354 KIIDVAIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAE 7533
I ++ + L ++N D D + +R+Y W +
Sbjct: 2962 YIRNLTTD-----GSHLSIVLQGLTNAVALDFDHSEKRLY------------WLDAGTRK 3004
Query: 7534 NPRLVF-GASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTIASGD 7710
R+ F G ++ A ++ + LDW+ +K+Y+T G V ++ G + + SG
Sbjct: 3005 IERMRFDGTDREVLANDVMAAEGLALDWVGRKLYWTDSYYGSVHVMELNGLYQRKLLSGH 3064
Query: 7711 W-----TY------ALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSES 7857
+ TY A+A++P G ++W+D G R+ + G + I++
Sbjct: 3065 FKEGNSTYIISRPRAVAVNPKYGWVYWTDWADMAYIG-------RAGMDGRNVSAIITTK 3117
Query: 7858 ISLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGY--RAKSLDIWDRWLYMS 8031
+ P+A+ +D+ +I++AD + ++ AD DGQNR G ++ +++ W+Y +
Sbjct: 3118 LEWPSALTIDYTTNRIFFADSHLNFLDFADMDGQNRHRAVGGTLPHVFAVSLFEDWVYWT 3177
Query: 8032 DPLSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNG 8211
D ++ V + K +G + ++ P + V+ R+ N C + +
Sbjct: 3178 DWNTHTVEKAHKYTGEMRTVMGNNTHRPYDIHVYHPYRQPRSENP---------CSSHHL 3228
Query: 8212 GCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSEPAKECLPPYN 8391
C LC IG + C C D + + + QCV S+++
Sbjct: 3229 TCSHLCL-----IGPGGQQASCECPDHFIGL---AVGFKIQCVADCSSTQ---------- 3270
Query: 8392 FQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHID 8571
F+CGD N +CI +C+
Sbjct: 3271 FRCGD----------------------------------------NEKCIPIWWECDGQS 3290
Query: 8572 DCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPGLPI 8751
DCGDGSDE C G F C + +C + +CDGH DC D SDE A C
Sbjct: 3291 DCGDGSDEPQTCPPRYCPVGQFQCQDRNCTHSGFICDGHADCPDH--SDEDAALCSDHR- 3347
Query: 8752 DCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCIPET 8931
C+ + +C N CI + CDG DC D +DE+ C + CA +C +GRC+P +
Sbjct: 3348 -CQENQFQCKNKK-CIPVSWHCDGVKDCSDNSDEDPETCSQKTCAPGQFQCANGRCLPSS 3405
Query: 8932 WQCDGDNDCSDGWDETHTNCTDTAGKKI-------------------------------C 9018
+ CD NDC D DE C+ + + C
Sbjct: 3406 YVCDFQNDCGDNSDEPLETCSKSRHVSVTQTWSLQKRKEITFFNIFLIMMLTFVMHFLSC 3465
Query: 9019 VGDYLFQCD--------NLKCISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQ-EFHCT 9171
++CD N +CI + GC + TC +F C
Sbjct: 3466 PVGPDYKCDETEFSCKTNYRCIPQ---WARCDGTNDCLDNSDEEGCEDVTCDPLGDFRCD 3522
Query: 9172 SNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECNKGEFRCSNQHCIHSTW 9351
+ + CIP W CDG+ C G DE + + C++ EFRC +Q CI +TW
Sbjct: 3523 N--------HRCIPIRWQCDGNNDCGDGSDERN----CQPRPCSESEFRCDSQQCIPATW 3570
Query: 9352 ECDGDNDCLDGSDEHANCTYSSCQ-PDFFQCANHKCVPNSWKCDGNDDCEDGSDEKDCPK 9528
CD NDC D SDE +C+ P F+CAN C+ C+ DDC DGSDE +
Sbjct: 3571 VCDHMNDCGDNSDERDCAATITCEMPSKFRCANGYCIFAGLLCNQKDDCGDGSDETE--- 3627
Query: 9529 NSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCE 9708
+ C+ +F+C++G C+ VCD N +C D +DE F ++ + EK LC+
Sbjct: 3628 DLCREPTLPPCTLDEFKCSNGHCVPLPYVCDHNDNCGDLTDELGCNFGNDRNCEEK-LCQ 3686
Query: 9709 QKCMDMK-IGYKCDCFEGFAIDISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDG 9885
C ++ G+ C C G+ ++ +C +++EC + C Q C + GSY C C G
Sbjct: 3687 HVCTNLNGTGFICSCKPGYKVNPDSTTTCLDIDEC-QIYGTCPQFCKNTKGSYDCECAPG 3745
Query: 9886 YQLSSDDHSCKRTEMEPEPF 9945
Y+ D C+ ++ PF
Sbjct: 3746 YRKVGDGKMCEAEDVR-NPF 3764
Score = 276 bits (706), Expect = 1e-71
Identities = 228/813 (28%), Positives = 333/813 (40%), Gaps = 13/813 (1%)
Frame = +1
Query: 11116 DKACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEADTLCMSAERNCTAEEFRCNNNKC 11295
D C F+C GRC P + +SDEA+ C C+ F C+N C
Sbjct: 840 DNNCGDNAFECDE-GRCRPNSYRCDGIIDCVDKSDEAN--CTDTGATCSPLAFTCDNKHC 896
Query: 11296 IAKAWRXXXXXXXXXXXXETPECAQIECKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDE 11475
I WR C+G DDC D SDE
Sbjct: 897 ILSGWR-----------------------------------------CDGLDDCGDGSDE 915
Query: 11476 DK--QRCPTCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEF 11649
+ PT F C + +CI + ++CD +NDCGD SDE +C T C + F
Sbjct: 916 MNCPTKTPTTCSADYFTC-DNYRCISKSFLCDGDNDCGDGSDE--HNCNSTITTCPPNYF 972
Query: 11650 RCNDGKCIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQCDDGT-CIAEHKWCDRKKDC 11826
C D +CI S VCDG C DG DE C C C G C++ CD DC
Sbjct: 973 LCPDHRCIYNSYVCDGDQDCLDGSDEKDCEFA-CASYEFACASGDQCVSSSYRCDGVFDC 1031
Query: 11827 PNAADELHCEDVSRRTCSPFEFECANS-VCIPRKFMXXXXXXXXXXSDETSSECRSAQCD 12003
+ +DE C C EF+C N CIP + SDE +S C C
Sbjct: 1032 RDHSDEQDCPTRGPGLCHDDEFQCQNDGFCIPGVWECDGHSDCEDGSDEHNS-CPPVTCR 1090
Query: 12004 PPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSFSEYGDCSSDQFKCANGK- 12180
P ++C ++LC+ C+G NDC D SDE F C S Q++C +
Sbjct: 1091 PNY-YQC-QNKLCIPTSWQCDGDNDC--LDMSDEQNCPTPPFR----CPSGQWQCPTDQL 1142
Query: 12181 CVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKHICTDVRDGFYCHCRDGF 12360
C++ CD + DC + +DE + NNGGC ICT G C C GF
Sbjct: 1143 CIDLDKVCDGQSDCPNGADESPICNQD-----DCILNNGGCSDICTQGPFGAQCSCPSGF 1197
Query: 12361 RPDPQSPKECIDIDECAGNNTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGD 12540
+ S K C DI+EC C+Q C N +GS+ C C E Y + G+ C+A
Sbjct: 1198 QLLNDS-KTCEDINECLIPGFCSQECYNERGSFRCYCSEGY-----LLEPDGRTCKAIDT 1251
Query: 12541 AANVMIGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERTIY 12720
V++ A S + + + R +YW D S++ I+
Sbjct: 1252 QDAVLLIAKRSQIIANWVNKKPPQMKPVVSGSSIVTVDFDRVTSR---IYWADASQKKIW 1308
Query: 12721 RSAIANGNQSHEGQKLDVDFAAMGVVPTAIAVDYTTGNLF-IAAVSENIENGLVTARKKR 12897
S+ NG E F+ +VP +IAVD+ NL+ +V ENIE
Sbjct: 1309 -SSYQNGTDKRE------VFSTGLMVPESIAVDWVGRNLYWTDSVMENIE---------- 1351
Query: 12898 MSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAP--SAGRICYSDAGLHAKIE 13071
V DGR+ K +++ ++ P L+ P + +SD G + +IE
Sbjct: 1352 --------------VSTLDGRFRKVLLSKNVTSPRGLVLDPRNHTNLMFWSDWGQNPRIE 1397
Query: 13072 CADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDR 13251
A MDGT RQ+IV ++ P +A+D +RIY+ D + +D + DGS R V+
Sbjct: 1398 RAFMDGTVRQVIVSTKLYWPNGLALDY-TTHRIYFADAYLKYIDYCSYDGSNRHQVMASN 1456
Query: 13252 HI---PYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDT 13422
+ P+ + +FEN++YW R + + +KF + + S + + + + T
Sbjct: 1457 MVLQHPHGMTIFENYVYWSERYTSKVMRTNKFHGSNFTTVMSSVYQPMGIVMDHPIKQPT 1516
Query: 13423 QRTVSGCERAQCSHLCV--SLPSTGFACLCPDG 13515
++ C+ LC+ L + C C G
Sbjct: 1517 VNSL-------CTQLCLLSGLRPRYYTCHCQSG 1542
Score = 264 bits (674), Expect = 5e-68
Identities = 190/683 (27%), Positives = 298/683 (42%), Gaps = 29/683 (4%)
Frame = +1
Query: 139 NTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHS 318
++ + C+ N+FRC+ GKCI W C Q+ C +
Sbjct: 2615 SSETRTCSMNEFRCDSGKCIPNSWVCDGIRDCQDGTDEPLSCGKSCAFVQFTCT-----N 2669
Query: 319 VSCIAEYQRCDNITDCADGSDEK---DCPASTVDCSSQNVFMCADG----RQCFDVSKKC 477
+CI ++ CD DC D SDE DC T CSS F C +C +S C
Sbjct: 2670 GNCIPQFMLCDGNNDCWDNSDEAVELDCGERT--CSSVQ-FTCPTWIPGFPKCLPISYVC 2726
Query: 478 DGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCE 657
DG+ DC + +DE +C + C +F C++ CI + CD DC DGSDE C
Sbjct: 2727 DGERDCANAADELRNCP--NRTCHLDEFSCSNGL-CILLPFHCDRVNDCGDGSDELG-CT 2782
Query: 658 FKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDE----CGEYRCPPGKWNCPGTGHC 825
+ C++N+F C N C F CD DC D SDE++ + C P ++ C +G C
Sbjct: 2783 YDTCSSNQFTCTNGACISSAFTCDGMSDCLDGSDEEDSLCVSPQPTCAPQQYMCT-SGQC 2841
Query: 826 IDQLKLCDGSKDCADGADEQQCSQNLC--PSL-GCQAGCHPSPHGGECTCPSGYKLDDRF 996
ID ++CDG KDC D +DE+ C N C PS+ C C + G C+C GY+L
Sbjct: 2842 IDTNRVCDGQKDCPDNSDEKGCGINECTNPSVHKCAQLCTDTLTGYYCSCQPGYRLMPD- 2900
Query: 997 HRTCSDINECAEF-GYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNN 1173
+ C DINEC+ C Q+C N + C C PG C N+
Sbjct: 2901 GKACEDINECSSTPAVCSQICENVVGSYYCKC-----------APGYIREADGRTCRQNS 2949
Query: 1174 ADKMKLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSA 1353
L + R + L + L +DFD+ +++++W D A +
Sbjct: 2950 GIAPYLLYSNRYYIRNLTTDGSHLSI-VLQGLTNAVALDFDHSEKRLYWLD-----AGTR 3003
Query: 1354 DVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLAD 1533
++ +++ ++ LA+DW+ LY +S + V +G + LL+
Sbjct: 3004 KIERMRFDGTDREVLANDVMAAEGLALDWVGRKLYWTDSYYGSVHVMELNGLYQRKLLSG 3063
Query: 1534 G---------LTLPLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVSG 1677
++ P +A++P G +++T + + A MDG N ++ T S
Sbjct: 3064 HFKEGNSTYIISRPRAVAVNPKYGWVYWTDWADMAYIGRAGMDGRNVSAIITTKLEWPSA 3123
Query: 1678 IVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTR 1857
+ +D T R+++ D ++ L+ D G +R G +PH F ++LF+ ++YWTDW
Sbjct: 3124 LTIDYTTNRIFFADSHLNFLDFADMDGQNRHRAVGG--TLPHVFAVSLFEDWVYWTDWNT 3181
Query: 1858 LGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCT--NAD 2031
V + K+ + + + N N P I YHP QP + ENPC+ +
Sbjct: 3182 HTVEKAHKYTGEMRTVMGN--NTHRPYDIHVYHPYRQP----------RSENPCSSHHLT 3229
Query: 2032 CEGMCILSKDNGGFGVGYKCACP 2100
C +C++ G G C CP
Sbjct: 3230 CSHLCLI----GPGGQQASCECP 3248
Score = 254 bits (649), Expect = 4e-65
Identities = 243/962 (25%), Positives = 380/962 (39%), Gaps = 112/962 (11%)
Frame = +1
Query: 1942 ISAYHPMAQPG----PGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQ 2109
++ Y+ QPG P C + E T A C +C Y C C G
Sbjct: 2884 LTGYYCSCQPGYRLMPDGKACEDIN-ECSSTPAVCSQIC------ENVVGSYYCKCAPGY 2936
Query: 2110 -KLVNGKRCIDS---IDYLLFSSNKIVRGIFPE-----INEKALAEAVLPISPISQRRIG 2262
+ +G+ C + YLL+S+ +R + + I + L AV S++R+
Sbjct: 2937 IREADGRTCRQNSGIAPYLLYSNRYYIRNLTTDGSHLSIVLQGLTNAVALDFDHSEKRL- 2995
Query: 2263 MYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWISKQLYYV 2442
++ D I R+R DG VL ++ DW+ ++LY+
Sbjct: 2996 --------------YWLDAGTRKIERMRFDGTDRE-VLANDVMAAEGLALDWVGRKLYWT 3040
Query: 2443 DNIRNSLEVVKIGETGLVHPDELVRRQLITE----------LRDPVSVVVHPWKGLLFYA 2592
D+ S+ V+++ + L +R+L++ + P +V V+P G +++
Sbjct: 3041 DSYYGSVHVMEL--------NGLYQRKLLSGHFKEGNSTYIISRPRAVAVNPKYGWVYWT 3092
Query: 2593 EAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKN 2772
+ A I R +DG+N I T L PS + ID+ NR+ + D+ L + D DG+N
Sbjct: 3093 DWADMAYIGRAGMDGRNVSAIITTKLEWPSALTIDYTTNRIFFADSHLNFLDFADMDGQN 3152
Query: 2773 VVKLDIDNPIP--VAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSL 2946
+ + +P A+++ +++Y+ +++ + HK G ++ G + + +
Sbjct: 3153 RHRA-VGGTLPHVFAVSLFEDWVYWTDWNTHTVEKAHKYTGEMRTVM---GNNTHRPYDI 3208
Query: 2947 KACSHQNQPIPDDSREHPCRASQ--CTQLCFATPSESHPNELEAKCACRQGFMINKENNH 3120
H P E+PC + C+ LC P +A C C +H
Sbjct: 3209 ----HVYHPYRQPRSENPCSSHHLTCSHLCLIGPGGQ-----QASCECP---------DH 3250
Query: 3121 SCQKDPAEKIEQLCSSNSTQFQC-KNGRCIPKEWKCDGENDCLDESDE------------ 3261
KI+ + +STQF+C N +CIP W+CDG++DC D SDE
Sbjct: 3251 FIGLAVGFKIQCVADCSSTQFRCGDNEKCIPIWWECDGQSDCGDGSDEPQTCPPRYCPVG 3310
Query: 3262 ---------------IDEKGDKCFHETE---------CAENTIKCRNTKKCIPAQXXXXX 3369
D D H E C EN +C+N KKCIP
Sbjct: 3311 QFQCQDRNCTHSGFICDGHADCPDHSDEDAALCSDHRCQENQFQCKN-KKCIPVSWHCDG 3369
Query: 3370 XXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCG 3549
+ C + CA +FQC N RC+P + E LE C
Sbjct: 3370 VKDCSDNSDEDPETCS---QKTCAPGQFQCANGRCLPSSYVCDFQNDCGDNSDEPLETCS 3426
Query: 3550 NAT-------------------------------------------CAANQFSC-ANGRC 3597
+ C +FSC N RC
Sbjct: 3427 KSRHVSVTQTWSLQKRKEITFFNIFLIMMLTFVMHFLSCPVGPDYKCDETEFSCKTNYRC 3486
Query: 3598 IPIYWLCDGDNDCYDGTDEDKERCPPVQCSAL-QFRCANGRQCVPLRNHXXXXXXXXXXX 3774
IP + CDG NDC D +DE E C V C L FRC N R C+P+R
Sbjct: 3487 IPQWARCDGTNDCLDNSDE--EGCEDVTCDPLGDFRCDNHR-CIPIRWQCDGNNDCGDGS 3543
Query: 3775 XXXXXAVTAESCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQF 3954
C+ +F+C S CIPA+W SDE T + S +F
Sbjct: 3544 DERN--CQPRPCSESEFRC-DSQQCIPATWVCDHMNDCGDNSDERDCAATITCEMPS-KF 3599
Query: 3955 KCGNGRCILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQ 4134
+C NG CI LC+ ++DCGDGSDE+ + + ++ C + C N C+PL
Sbjct: 3600 RCANGYCIFAGLLCNQKDDCGDGSDETEDLCREPTLPP--CTLDEFKCSNGH--CVPLPY 3655
Query: 4135 LCDGKTHCPGGTDEGGRCARDLCSADRAGCSFKCHN-SPNGPICSCPFGEQLV--NKTKC 4305
+CD +C TDE G + + + C C N + G ICSC G ++ + T C
Sbjct: 3656 VCDHNDNCGDLTDELGCNFGNDRNCEEKLCQHVCTNLNGTGFICSCKPGYKVNPDSTTTC 3715
Query: 4306 EPENECLDSSSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIY 4485
+EC +C Q CK+ K + C C GY D + C+ A++V++ + +Y
Sbjct: 3716 LDIDECQIYGTCPQFCKNTKGSYDCECAPGYRKVGDGKMCE-AEDVRNPFSVCVFEDHVY 3774
Query: 4486 YS 4491
+S
Sbjct: 3775 WS 3776
Score = 179 bits (453), Expect = 2e-42
Identities = 104/286 (36%), Positives = 138/286 (47%), Gaps = 10/286 (3%)
Frame = +1
Query: 262 PHPGCKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCA 441
P C ++ C T + CI ++ RCD DC D SDE+ C V C F C
Sbjct: 3469 PDYKCDETEFSCKT----NYRCIPQWARCDGTNDCLDNSDEEGC--EDVTCDPLGDFRC- 3521
Query: 442 DGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKD 621
D +C + +CDG DC D SDE++ R C + +FRC D QCI +WVCD D
Sbjct: 3522 DNHRCIPIRWQCDGNNDCGDGSDERNCQPR---PCSESEFRC-DSQQCIPATWVCDHMND 3577
Query: 622 CADGSDEPDTCEFKKCTA-NEFQCKNKRCQPRKFRCDYYDDCGDNSDEDE--CGEYRCPP 792
C D SDE D C ++F+C N C C+ DDCGD SDE E C E PP
Sbjct: 3578 CGDNSDERDCAATITCEMPSKFRCANGYCIFAGLLCNQKDDCGDGSDETEDLCREPTLPP 3637
Query: 793 ---GKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCS---QNLCPSLGCQAGC-HPSPHG 951
++ C GHC+ +CD + +C D DE C+ C CQ C + + G
Sbjct: 3638 CTLDEFKC-SNGHCVPLPYVCDHNDNCGDLTDELGCNFGNDRNCEEKLCQHVCTNLNGTG 3696
Query: 952 GECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSC 1089
C+C GYK++ TC DI+EC +G C Q C N + + C C
Sbjct: 3697 FICSCKPGYKVNPDSTTTCLDIDECQIYGTCPQFCKNTKGSYDCEC 3742
Score = 156 bits (394), Expect = 2e-35
Identities = 92/262 (35%), Positives = 119/262 (45%), Gaps = 47/262 (17%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDE-KDCPASTVDCSSQNVFMCADGR 450
C S Q++C + CI + CD +DC DGSDE + CP F C D R
Sbjct: 3266 CSSTQFRCGD----NEKCIPIWWECDGQSDCGDGSDEPQTCPPRYCPVGQ---FQCQD-R 3317
Query: 451 QCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCAD 630
C CDG DC D SDE + +H C + QF+C +K +CI SW CDG KDC+D
Sbjct: 3318 NCTHSGFICDGHADCPDHSDEDAALCSDHR-CQENQFQCKNK-KCIPVSWHCDGVKDCSD 3375
Query: 631 GSDE-PDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDE--DECG--------- 774
SDE P+TC K C +FQC N RC P + CD+ +DCGDNSDE + C
Sbjct: 3376 NSDEDPETCSQKTCAPGQFQCANGRCLPSSYVCDFQNDCGDNSDEPLETCSKSRHVSVTQ 3435
Query: 775 ----------------------------------EYRCPPGKWNCPGTGHCIDQLKLCDG 852
+Y+C +++C CI Q CDG
Sbjct: 3436 TWSLQKRKEITFFNIFLIMMLTFVMHFLSCPVGPDYKCDETEFSCKTNYRCIPQWARCDG 3495
Query: 853 SKDCADGADEQQCSQNLCPSLG 918
+ DC D +DE+ C C LG
Sbjct: 3496 TNDCLDNSDEEGCEDVTCDPLG 3517
Score = 145 bits (365), Expect = 4e-32
Identities = 114/404 (28%), Positives = 157/404 (38%), Gaps = 87/404 (21%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEW--XXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCI 330
C + F C +G CI W C + ++ CD + C+
Sbjct: 2426 CQADQFTCLNGHCISVSWKCDGYNDCQDNSDELERVCAFHTCSATEFVCD-----NGRCV 2480
Query: 331 AEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRD--- 501
CD DC D SDE+ CP T C+ F C +GR C CDG DCRD
Sbjct: 2481 PLSYVCDYTNDCRDNSDERGCPFPT--CNPTTEFTCDNGR-CISADFICDGHNDCRDNAT 2537
Query: 502 -----------------------------LSDEKDSCSRN-------------------- 534
L D ++C N
Sbjct: 2538 SDEINCPDRTCPDGLVKCDHTNICIYPGNLCDGYNNCGDNSDENPLFCGKINNALLSFIR 2597
Query: 535 ----HTACF--QYQFRCADKTQ-------------CIQKSWVCDGSKDCADGSDEPDTCE 657
+ CF +Y C+ +T+ CI SWVCDG +DC DG+DEP +C
Sbjct: 2598 IDMLNILCFTDKYLNLCSSETRTCSMNEFRCDSGKCIPNSWVCDGIRDCQDGTDEPLSCG 2657
Query: 658 FKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDED---ECGEYRCPPGKWNC----PGT 816
K C +F C N C P+ CD +DC DNSDE +CGE C ++ C PG
Sbjct: 2658 -KSCAFVQFTCTNGNCIPQFMLCDGNNDCWDNSDEAVELDCGERTCSSVQFTCPTWIPGF 2716
Query: 817 GHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRF 996
C+ +CDG +DCA+ ADE + CP+ C H E +C +G + F
Sbjct: 2717 PKCLPISYVCDGERDCANAADELR----NCPNRTC--------HLDEFSCSNGLCILLPF 2764
Query: 997 HRTCSDINECA----EFGYCDQLCANHRPGFTC---SCLGDCFT 1107
H C +N+C E G C++++ FTC +C+ FT
Sbjct: 2765 H--CDRVNDCGDGSDELGCTYDTCSSNQ--FTCTNGACISSAFT 2804
Score = 140 bits (352), Expect = 1e-30
Identities = 74/211 (35%), Positives = 102/211 (48%), Gaps = 19/211 (9%)
Frame = +1
Query: 325 CIAEYQRCDNITDCADGSDEKDCPAS--------------TVDCSSQNVFMCADGRQCFD 462
C + + C ++ G + C DCSS F C D +C
Sbjct: 3223 CSSHHLTCSHLCLIGPGGQQASCECPDHFIGLAVGFKIQCVADCSSTQ-FRCGDNEKCIP 3281
Query: 463 VSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDE 642
+ +CDG+ DC D SDE +C + C QF+C D+ C ++CDG DC D SDE
Sbjct: 3282 IWWECDGQSDCGDGSDEPQTCPPRY--CPVGQFQCQDRN-CTHSGFICDGHADCPDHSDE 3338
Query: 643 PDT-CEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDE--CGEYRCPPGKWNCPG 813
C +C N+FQCKNK+C P + CD DC DNSDED C + C PG++ C
Sbjct: 3339 DAALCSDHRCQENQFQCKNKKCIPVSWHCDGVKDCSDNSDEDPETCSQKTCAPGQFQC-A 3397
Query: 814 TGHCIDQLKLCDGSKDCADGADE--QQCSQN 900
G C+ +CD DC D +DE + CS++
Sbjct: 3398 NGRCLPSSYVCDFQNDCGDNSDEPLETCSKS 3428
Score = 127 bits (318), Expect = 1e-26
Identities = 73/172 (42%), Positives = 88/172 (50%), Gaps = 3/172 (1%)
Frame = +1
Query: 376 SDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQY 555
+D KDC T + F C +G C VS KCDG DC+D SDE + HT C
Sbjct: 2413 NDGKDCIQDTGKRCQADQFTCLNGH-CISVSWKCDGYNDCQDNSDELERVCAFHT-CSAT 2470
Query: 556 QFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCT-ANEFQCKNKRCQPRKFRCDY 732
+F C D +C+ S+VCD + DC D SDE C F C EF C N RC F CD
Sbjct: 2471 EFVC-DNGRCVPLSYVCDYTNDCRDNSDERG-CPFPTCNPTTEFTCDNGRCISADFICDG 2528
Query: 733 YDDCGDN--SDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADE 882
++DC DN SDE C + CP G C T CI LCDG +C D +DE
Sbjct: 2529 HNDCRDNATSDEINCPDRTCPDGLVKCDHTNICIYPGNLCDGYNNCGDNSDE 2580
Score = 124 bits (312), Expect = 5e-26
Identities = 66/161 (40%), Positives = 81/161 (49%), Gaps = 4/161 (2%)
Frame = +1
Query: 544 CFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFR 723
C QFRC D +CI W CDG DC DGSDEP TC + C +FQC+++ C F
Sbjct: 3266 CSSTQFRCGDNEKCIPIWWECDGQSDCGDGSDEPQTCPPRYCPVGQFQCQDRNCTHSGFI 3325
Query: 724 CDYYDDCGDNSDEDE--CGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADE--QQC 891
CD + DC D+SDED C ++RC ++ C CI CDG KDC+D +DE + C
Sbjct: 3326 CDGHADCPDHSDEDAALCSDHRCQENQFQCKNK-KCIPVSWHCDGVKDCSDNSDEDPETC 3384
Query: 892 SQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSD 1014
SQ C Q G C PS Y D F C D
Sbjct: 3385 SQKTCAPGQFQCA------NGRC-LPSSYVCD--FQNDCGD 3416
Score = 115 bits (288), Expect = 3e-23
Identities = 72/221 (32%), Positives = 89/221 (39%), Gaps = 1/221 (0%)
Frame = +1
Query: 373 GSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQ 552
GS ++ C +S + +C G + DG + + D KD C
Sbjct: 2371 GSKQEMCSSSCQQFNGGCSHICVSGPSGPECQCPHDGSWYLAN--DGKDCIQDTGKRCQA 2428
Query: 553 YQFRCADKTQCIQKSWVCDGSKDCADGSDEPD-TCEFKKCTANEFQCKNKRCQPRKFRCD 729
QF C + CI SW CDG DC D SDE + C F C+A EF C N RC P + CD
Sbjct: 2429 DQFTCLNG-HCISVSWKCDGYNDCQDNSDELERVCAFHTCSATEFVCDNGRCVPLSYVCD 2487
Query: 730 YYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCP 909
Y +DC DNSDE C C P G CI +CDG DC D A + + CP
Sbjct: 2488 YTNDCRDNSDERGCPFPTCNPTTEFTCDNGRCISADFICDGHNDCRDNATSDEIN---CP 2544
Query: 910 SLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAE 1032
C G H C P C N C +
Sbjct: 2545 DRTCPDGLVKCDHTNICIYPG---------NLCDGYNNCGD 2576
Score = 97.8 bits (242), Expect = 7e-18
Identities = 79/274 (28%), Positives = 110/274 (39%), Gaps = 3/274 (1%)
Frame = +1
Query: 169 DFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAEYQRC 348
DFRC++ +CI W C +++CD S CI C
Sbjct: 3518 DFRCDNHRCIPIRWQCDGNNDCGDGSDERNCQPRPCSESEFRCD-----SQQCIPATWVC 3572
Query: 349 DNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCS 528
D++ DC D SDE+DC A+T+ C + F CA+G C C+ K DC D SDE +
Sbjct: 3573 DHMNDCGDNSDERDC-AATITCEMPSKFRCANG-YCIFAGLLCNQKDDCGDGSDETEDLC 3630
Query: 529 RNHT--ACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKR 702
R T C +F+C++ C+ +VCD + +C D +DE C F N+ C+ K
Sbjct: 3631 REPTLPPCTLDEFKCSN-GHCVPLPYVCDHNDNCGDLTDELG-CNF----GNDRNCEEKL 3684
Query: 703 CQPRKFRCDYYDDCGDNSDEDECGEYRCPPG-KWNCPGTGHCIDQLKLCDGSKDCADGAD 879
CQ C + G C PG K N T C+D D
Sbjct: 3685 CQ---HVCTNLNGTGFICS--------CKPGYKVNPDSTTTCLD--------------ID 3719
Query: 880 EQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYK 981
E Q CP C + +C C GY+
Sbjct: 3720 ECQI-YGTCPQF-----CKNTKGSYDCECAPGYR 3747
Score = 88.2 bits (217), Expect = 5e-15
Identities = 51/170 (30%), Positives = 75/170 (44%)
Frame = +1
Query: 9262 ESTELCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQC 9441
E L K E+ C +F C C+ +++ CD DCLD SDE+ NC Y C C
Sbjct: 16 EGIHLVKGERT-CGSDQFTCQEGQCVPASYRCDHVKDCLDNSDEN-NCNYPPCTER--TC 71
Query: 9442 ANHKCVPNSWKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCD 9621
AN C NS C+G DC DGSDE +C + + Q + C D V +
Sbjct: 72 ANGACYNNSQHCNGLQDCRDGSDEFNCSLQRCATLSCEYMCHPSPQGGACYCPDGFTVAN 131
Query: 9622 RNFDCTDRSDESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAID 9771
+ C D D+C + +C+ C D ++C C +G+ ++
Sbjct: 132 DSRSCVD---------YDDCQI--WGICDHLCEDRPGSHQCSCADGYFLE 170
Score = 79.3 bits (194), Expect = 2e-12
Identities = 52/163 (31%), Positives = 66/163 (39%), Gaps = 10/163 (6%)
Frame = +1
Query: 529 RNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQ 708
+ C QF C + QC+ S+ CD KDC D SDE + C + CT E C N C
Sbjct: 22 KGERTCGSDQFTCQEG-QCVPASYRCDHVKDCLDNSDE-NNCNYPPCT--ERTCANGACY 77
Query: 709 PRKFRCDYYDDCGDNSDEDECG---------EYRCPPGKWNCPGTGHCIDQLKLCDGSKD 861
C+ DC D SDE C EY C P G +C D + + S+
Sbjct: 78 NNSQHCNGLQDCRDGSDEFNCSLQRCATLSCEYMCHPSPQG--GACYCPDGFTVANDSRS 135
Query: 862 CADGADEQQCSQNLCPSLG-CQAGCHPSPHGGECTCPSGYKLD 987
C D D C G C C P +C+C GY L+
Sbjct: 136 CVDYDD--------CQIWGICDHLCEDRPGSHQCSCADGYFLE 170
Score = 73.6 bits (179), Expect = 1e-10
Identities = 113/489 (23%), Positives = 190/489 (38%), Gaps = 32/489 (6%)
Frame = +1
Query: 12289 NNGGCKHIC-----TDVRD-GFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTK 12450
+NGGC+HIC TD GF C CR G+ D + + TC ++
Sbjct: 484 HNGGCQHICVLSHRTDNDGLGFRCKCRHGY-------------DLHSDHRTCFKV----- 525
Query: 12451 GSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGSGTNRHXXXXX 12630
+D+ + +G N+ + D + L L G T+
Sbjct: 526 --------KDF-------LLIASSLAVRGIPLNLSLQED---LTLPLSGLATSFSGSAVE 567
Query: 12631 XXXXXXXXXXXXXPRKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTAI 12810
KE +++ D S +Y+S + NG Q++ + +GV+ A+
Sbjct: 568 FDGI-----------KESIFYNDRSRGLVYKSNL-NGTV----QEILTGYR-VGVID-AM 609
Query: 12811 AVDYTTGNLF-IAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGH 12987
A D+T+ LF + +++ VT + +R IV G
Sbjct: 610 AYDWTSNILFWTTSTYQSVVAFKVTDKSRR------------------------DIVTG- 644
Query: 12988 LQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNR 13167
L+ P + PSAG + +SD A I A DG++ +V + P +A+D +R
Sbjct: 645 LRYPKGIAVHPSAGYLFWSDWYRPAVIMRAFTDGSNAIPLVNTTLGWPYGLALDYIT-DR 703
Query: 13168 IYWVDPKYRRVDAVNIDGSERTTVVHDRHI--PYAVDVFENHIYWLSRESKTLY-VQDKF 13338
+YWVD + +V ++I GS+R T + I PY++ V+ +++Y ++++Y ++ +
Sbjct: 704 LYWVDSQLDQVGHIDIQGSDRQTFTNIGEITQPYSLTVYTDYLYVADTRTRSIYEMRKRD 763
Query: 13339 GRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCER---AQCSHLCVSLPSTGFACLCP 13509
G G V V G T ++ K + C + QCSH C +P C CP
Sbjct: 764 GGGSVVV-----RRGITAIMNIKAYTPELHSCIRCTKPPNGQCSHFCFPVPPFSRKCGCP 818
Query: 13510 DGI--------------VPQLDGSCATQHVEALTMPKQCKCTNGGKC-----RLDGSCEC 13632
G+ VP D +C E + G+C R DG +C
Sbjct: 819 YGMKLQDNKRDCIKDDSVPPPDNNCGDNAFEC----------DEGRCRPNSYRCDGIIDC 868
Query: 13633 TSDFEGDQC 13659
+ C
Sbjct: 869 VDKSDEANC 877
Score = 70.9 bits (172), Expect = 9e-10
Identities = 54/196 (27%), Positives = 86/196 (43%), Gaps = 8/196 (4%)
Frame = +1
Query: 13105 IVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDVFEN 13284
I+ + +P ++ID + +YW D +++ + G R ++H PYA+ VF+
Sbjct: 2271 IINSSLTTPNGLSIDYEE-RMLYWADASLDKIERATLTGENRHIILHGVVYPYAMTVFQQ 2329
Query: 13285 HIYWLSRESKTLYVQDKFGRGRVSVLASDLE----DGHTVRVSQKYAKDTQRTVSGCER- 13449
I+W + ++ K G +VLA DL+ D H S++ + S C++
Sbjct: 2330 DIFWTDWTERAVFRARKDGGSGFAVLAQDLQYRPNDIHVYAGSKQ-----EMCSSSCQQF 2384
Query: 13450 -AQCSHLCVSLPSTGFACLCP-DGI-VPQLDGSCATQHVEALTMPKQCKCTNGGKCRLDG 13620
CSH+CVS PS G C CP DG DG Q Q C NG +
Sbjct: 2385 NGGCSHICVSGPS-GPECQCPHDGSWYLANDGKDCIQDTGKRCQADQFTCLNGHCISVSW 2443
Query: 13621 SCECTSDFEGDQCEKE 13668
C+ +D + + E E
Sbjct: 2444 KCDGYNDCQDNSDELE 2459
Score = 67.8 bits (164), Expect = 7e-09
Identities = 77/395 (19%), Positives = 159/395 (39%), Gaps = 15/395 (3%)
Frame = +1
Query: 12415 NNTCTQLCLNT---KGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQL 12585
N+ CTQLCL + Y C C ++ + K K ++ +M+ + + +
Sbjct: 1518 NSLCTQLCLLSGLRPRYYTCHCQSGWKLDA------DKRTCIKDESTFLMVVRESVIFGI 1571
Query: 12586 SLHGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERTIYRSAIANGNQSHEGQK 12765
L + + + ++EL+YW+ + +I++ + N+S
Sbjct: 1572 PLDPNDPSNNAMTPVSGISQGQDIDFDD-QEELVYWVQNTG-SIWKVKTSGTNRS----- 1624
Query: 12766 LDVDFAAMGVV--PTAIAVDYTTGNLFIA-AVSENIE----NGLVTARKKRMSEPIDNQN 12924
+FA ++ P+ +A D+ T +F ++IE +G RK ++ +
Sbjct: 1625 ---EFAPAAIMGSPSGLAFDWITRMMFYTNPTGKSIEVIRVDGSQHYRKTLITSTGKPEE 1681
Query: 12925 TGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAG---LHAKIECADMDGTH 13095
TG QP + P+ G++ ++D G + K+ ADMDG +
Sbjct: 1682 TG---------------------QPIGIAVDPARGKLFWTDKGSENVPPKVGSADMDGGN 1720
Query: 13096 RQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDV 13275
+ + + + + + D +++YW ++ +DG + TVV P+ + V
Sbjct: 1721 LKNLYTENLANIGVLTADIS-ASKLYWGVSGSGVIECGTMDGLTKVTVVSGLSHPWGLTV 1779
Query: 13276 FENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGC--ER 13449
+N++Y+ + + + DK + V+ S + ++V + D+ T + C
Sbjct: 1780 HQNYLYYTDLDYEVIERVDKNSGANMVVMRSGMSGLRALKVHTR--DDSAGTDNACSSNN 1837
Query: 13450 AQCSHLCVSLPSTGFACLCPDGIVPQLDGSCATQH 13554
C+ LC+ P C C G + DG+ Q+
Sbjct: 1838 GGCAQLCLPKPDHQKTCACTTGFIMSPDGTRCEQY 1872
Score = 66.6 bits (161), Expect = 2e-08
Identities = 42/127 (33%), Positives = 60/127 (47%), Gaps = 5/127 (3%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQ 453
C SDQ+ C C+ RCD++ DC D SDE +C + C+ + CA+G
Sbjct: 27 CGSDQFTCQ-----EGQCVPASYRCDHVKDCLDNSDENNC--NYPPCTERT---CANG-A 75
Query: 454 CFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQ-----CIQKSWVCDGSK 618
C++ S+ C+G DCRD SDE +CS A ++ C Q C V + S+
Sbjct: 76 CYNNSQHCNGLQDCRDGSDE-FNCSLQRCATLSCEYMCHPSPQGGACYCPDGFTVANDSR 134
Query: 619 DCADGSD 639
C D D
Sbjct: 135 SCVDYDD 141
Score = 62.8 bits (151), Expect = 2e-07
Identities = 79/386 (20%), Positives = 144/386 (36%), Gaps = 16/386 (4%)
Frame = +1
Query: 12406 CAGNNT-CTQLCL-NTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDSLV 12579
C+ NN C QLCL C C + + S G C A ++ D +
Sbjct: 1833 CSSNNGGCAQLCLPKPDHQKTCACTTGF-----IMSPDGTRCEQYESYA--VVSTDKYIR 1885
Query: 12580 QLSLHGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSE----RTIYRSAIANGNQ 12747
++ S + + +Y+ID S R IYR+ + G
Sbjct: 1886 GFHINSSDHSEAMVPISGSSYSVKGTMDLHIQSGFVYYIDNSTYSSYRGIYRTKTSGGFT 1945
Query: 12748 SHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNT 12927
+ + + +G+ +AVD+ TGNL+ E+ + + + N
Sbjct: 1946 T---RVIGSGIGKLGI--QGLAVDWITGNLYFTNAFES---------ETLLEVHVINTTN 1991
Query: 12928 GFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQII 13107
I + + H QP L +P + ++D G KIE A +DGT+R ++
Sbjct: 1992 RMIL-----------LKSSH-DQPRDLAVSPKLRYLFWTDGGQTPKIERALLDGTNRTVL 2039
Query: 13108 VKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHI--PYAVDVFE 13281
+ + SP + +D + +YW D + + DGS+R + + P V +
Sbjct: 2040 ASESLASPRGLTVDY-TNDFLYWTDDVLDMISRMASDGSQRQIIRYGSRYPSPVGVAILG 2098
Query: 13282 NHIYWLSRESKTLYVQDK--FGRGRVSVLASDLEDGHTVRVSQKYAKDT---QRTVSGC- 13443
N++ W+ ++ L+ K + V+ +L+ + + + + T Q + C
Sbjct: 2099 NNMLWVDKKLGKLFQASKGNTSSAQPEVIRDNLDGLMDIAIFDVHVQPTASHQVAFNPCY 2158
Query: 13444 -ERAQCSHLCVSLPSTGF-ACLCPDG 13515
C LC ++P C C G
Sbjct: 2159 EHNGGCQQLCFAIPDQDHPKCGCAHG 2184
Score = 60.1 bits (144), Expect = 2e-06
Identities = 47/188 (25%), Positives = 79/188 (42%), Gaps = 12/188 (6%)
Frame = +1
Query: 12988 LQQPTALITAPSAGRICYSDAGL---HAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGK 13158
L++P L + ++D G K+E A MDG++R +VK + P ++ +D
Sbjct: 327 LEKPRILTLLCVCSYMFFTDMGTATEQVKLERAFMDGSNRVELVKKRLGIPAAITVDIVT 386
Query: 13159 GNRIYWVDPKYRRVDAVNIDGSERTTVVH---DRHIPYAVDVFENHIYWLSRESKTLYVQ 13329
R+YW D + V+ V G +R V++ P+ + FENH+++ +
Sbjct: 387 -KRVYWTDIHFDTVETVTYSGLDRKIVLNGGTKAPYPFGIATFENHLFFTDWTKMGVMKA 445
Query: 13330 DKFGRGRVSVL-ASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPST-----G 13491
++F ++ + GH V VS + G C H+CV T G
Sbjct: 446 NRFKENNPELIYRTTRRPGHVV-VSHSVLQPVVMNPCGRHNGGCQHICVLSHRTDNDGLG 504
Query: 13492 FACLCPDG 13515
F C C G
Sbjct: 505 FRCKCRHG 512
Score = 58.2 bits (139), Expect = 6e-06
Identities = 51/188 (27%), Positives = 69/188 (36%), Gaps = 23/188 (12%)
Frame = +1
Query: 9133 GNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECNK-- 9306
G RTC +F C +C+P ++ CD C DE+ CN
Sbjct: 23 GERTCGSDQFTCQEG--------QCVPASYRCDHVKDCLDNSDEN---------NCNYPP 65
Query: 9307 -GEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQ-------------------P 9426
E C+N C +++ C+G DC DGSDE NC+ C P
Sbjct: 66 CTERTCANGACYNNSQHCNGLQDCRDGSDEF-NCSLQRCATLSCEYMCHPSPQGGACYCP 124
Query: 9427 DFFQCANHKCVPNSWKCDGNDDCED-GSDEKDCPKNSASAQKASKCSNGQFQCTSGECID 9603
D F AN +S C DDC+ G + C S Q CS C G ++
Sbjct: 125 DGFTVAN-----DSRSCVDYDDCQIWGICDHLCEDRPGSHQ----CS-----CADGYFLE 170
Query: 9604 DAKVCDRN 9627
+C N
Sbjct: 171 QGHICKAN 178
Score = 51.6 bits (122), Expect = 6e-04
Identities = 22/56 (39%), Positives = 31/56 (55%)
Frame = +1
Query: 3547 GNATCAANQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANG 3714
G TC ++QF+C G+C+P + CD DC D +DE+ PP + CANG
Sbjct: 23 GERTCGSDQFTCQEGQCVPASYRCDHVKDCLDNSDENNCNYPP----CTERTCANG 74
Score = 50.4 bits (119), Expect = 0.001
Identities = 25/70 (35%), Positives = 35/70 (49%), Gaps = 4/70 (5%)
Frame = +1
Query: 3145 KIEQLCSSNSTQFQCKNGRCIPKEWKCDGENDCLDESDEIDEKGDKCFHET----ECAEN 3312
K E+ C S+ QF C+ G+C+P ++CD DCLD SDE + C T C N
Sbjct: 22 KGERTCGSD--QFTCQEGQCVPASYRCDHVKDCLDNSDENNCNYPPCTERTCANGACYNN 79
Query: 3313 TIKCRNTKKC 3342
+ C + C
Sbjct: 80 SQHCNGLQDC 89
Score = 49.7 bits (117), Expect = 0.002
Identities = 46/178 (25%), Positives = 66/178 (36%), Gaps = 15/178 (8%)
Frame = +1
Query: 11239 MSAERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXET----PECAQIECKKGWTRCSS 11406
+ ER C +++F C +C+ ++R E P C + C G
Sbjct: 21 VKGERTCGSDQFTCQEGQCVPASYRCDHVKDCLDNSDENNCNYPPCTERTCANG------ 74
Query: 11407 SYRCIPNWAFCNGQDDCRDNSDE---DKQRCPTCDDVGEFRCATSGK-----CIPRRWMC 11562
C N CNG DCRD SDE QRC T E+ C S + C +
Sbjct: 75 --ACYNNSQHCNGLQDCRDGSDEFNCSLQRCATLS--CEYMCHPSPQGGACYCPDGFTVA 130
Query: 11563 DTENDCGDNSD-ELDASCGG--TTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDE 11727
+ C D D ++ C RP S + C DG + +C + S GL +
Sbjct: 131 NDSRSCVDYDDCQIWGICDHLCEDRPGSH-QCSCADGYFLEQGHICKANV--SGGLPQ 185
Score = 45.8 bits (107), Expect = 0.030
Identities = 22/55 (40%), Positives = 32/55 (58%)
Frame = +1
Query: 13183 PKYRRVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSRESKTLYVQDKFGRG 13347
P YR+V G + D P++V VFE+H+YW ++E ++ QDKFGRG
Sbjct: 3744 PGYRKV------GDGKMCEAEDVRNPFSVCVFEDHVYWSTQEKGEVFRQDKFGRG 3792
Score = 45.4 bits (106), Expect = 0.040
Identities = 26/84 (30%), Positives = 34/84 (39%), Gaps = 8/84 (9%)
Frame = +1
Query: 13441 CERAQCSHLCVSLPSTGFACLCPDGIVPQLDGSCATQHVEAL----TMPKQCKCTNGGKC 13608
CE C H+C +L TGF C C G D + ++ T P+ CK T G
Sbjct: 3680 CEEKLCQHVCTNLNGTGFICSCKPGYKVNPDSTTTCLDIDECQIYGTCPQFCKNTKGSY- 3738
Query: 13609 RLDGSCECTSDF----EGDQCEKE 13668
CEC + +G CE E
Sbjct: 3739 ----DCECAPGYRKVGDGKMCEAE 3758
>gi|6678720|ref|NP_032538.1| low density lipoprotein receptor-related
protein 1; alpha 2-macroglobulin receptor [Mus musculus]
gi|109553|pir||S25111 alpha-2-macroglobulin receptor precursor - mouse
gi|49942|emb|CAA47817.1| AM2 receptor [Mus musculus]
Length = 4545
Score = 1998 bits (5175), Expect = 0.0
Identities = 1381/4508 (30%), Positives = 2092/4508 (45%), Gaps = 174/4508 (3%)
Frame = +1
Query: 661 KKCTANEFQCKNK-RCQPRKFRCDYYDDCGDNSDE-----DECGEYRCPPGKWNCPGTGH 822
K C+ +F C+++ C + +RCD DC D SDE + RCPP + +C GT
Sbjct: 26 KTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEHSCLGTEL 85
Query: 823 CIDQLKLCDGSKDCADGADEQQCSQNL---CPSLGCQAGCHPSPHGGECTCPSGYKLDDR 993
C+ +LC+G +DC DG+DE + L C +GCQ C P+P G C C S ++L+
Sbjct: 86 CVPMSRLCNGIQDCMDGSDEGAHCRELRANCSRMGCQHHCVPTPSGPTCYCNSSFQLEAD 145
Query: 994 FHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNN 1173
+TC D +EC+ +G C QLC N FTC C+ + + LQ DN + C + N
Sbjct: 146 -GKTCKDFDECSVYGTCSQLCTNTDGSFTCGCV-EGYLLQ------PDNRS----CKAKN 193
Query: 1174 ADKMK---LFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSA 1344
+ L +A + + S +DF Y + + W + SA
Sbjct: 194 EPVDRPPVLLIANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWV-HVGDSA 252
Query: 1345 FSADVD-----------DEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDV 1491
+ DE I+ +SL SL + +A+DW+T Y ++ RI V
Sbjct: 253 AQTQLKCARMPGLKGFVDEHTIN----ISL-SLHHVEQMAIDWLTGNFYFVDDIDDRIFV 307
Query: 1492 SSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTNQ---LKLEAAAMDGTNRRTLVNTHT 1662
+ +G+ LL L P IALDP G++FFT+ K+E MDG NR LV++
Sbjct: 308 CNRNGDTCVTLLDLELYNPKGIALDPAMGKVFFTDYGQIPKVERCDMDGQNRTKLVDSKI 367
Query: 1663 HQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYW 1842
GI +D+ ++ VYW D +D +E +DY+G R+ + QG+ ++ H +GL +F+ YLY
Sbjct: 368 VFPHGITLDLVSRLVYWADAYLDYIEVVDYEGKGRQTIIQGI-LIEHLYGLTVFENYLYA 426
Query: 1843 TD------WTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMK 2004
T+ + VI+V +F S + + + + YH QP C +
Sbjct: 427 TNSDNANTQQKTSVIRVNRFNSTEYQVVTRVDKGG---ALHIYHQRRQPRVRSHACENDQ 483
Query: 2005 IENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKL-VNGKRCIDSIDYLLFSSNK--- 2172
P C +C+L+ + C C G L +GK C L K
Sbjct: 484 YGKP---GGCSDICLLANSHKA----RTCRCRSGFSLGSDGKSCKKPEHELFLVYGKGRP 536
Query: 2173 -IVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFF--YADIMDNTIYRI 2343
I+RG+ ++ K E ++PI + R D H + F +AD I R
Sbjct: 537 GIIRGM--DMGAKVPDEHMIPIENLMNPRA-------LDFHAETGFIYFADTTSYLIGRQ 587
Query: 2344 RPDGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDN-IRNSLEVVKIGETGLVHPDELVRR 2520
+ DG +L + ++ DW+ LY+ D+ + ++ V ++ + R+
Sbjct: 588 KIDGTERETILKDGIHNVEGVAVDWMGDNLYWTDDGPKKTISVARLEKAAQT------RK 641
Query: 2521 QLIT-ELRDPVSVVVHPWKGLLFYAE------AMRPAAIYRCHIDGQNCQV-IRNTTLGR 2676
LI ++ P ++VV P G +++ + R + R +DG + + + + T+
Sbjct: 642 TLIEGKMTHPRAIVVDPLNGWMYWTDWEEDPKDSRRGRLERAWMDGSHRDIFVTSKTVLW 701
Query: 2677 PSEMAIDFAENRLCWGDTLLKTISCMDFDG--KNVVKLDIDNPIPVAITIMNEYIYYVHQ 2850
P+ +++D RL W D I + +G + +V + + Y+++
Sbjct: 702 PNGLSLDIPAGRLYWVDAFYDRIETILLNGTDRKIVYEGPELNHAFGLCHHGNYLFWTEY 761
Query: 2851 RPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQ--CTQ 3024
R S+ R+ + G V ++ IF ++ Q + + CR + C+
Sbjct: 762 RSGSVYRLERGVAGAPPTVTLLRSERPPIFEIRMYDAHEQQVGTNK----CRVNNGGCSS 817
Query: 3025 LCFATPSESHPNELEAKCACRQGFMINKENNHSCQKDPAEKIEQLCSSNSTQFQCKNGRC 3204
LC ATP +CAC + +++ + +C +P+ C QF C N RC
Sbjct: 818 LCLATPGSR-------QCACAEDQVLDTDGV-TCLANPSYVPPPQCQPG--QFACANNRC 867
Query: 3205 IPKEWKCDGENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKKCIPAQXXXXXXXXXX 3384
I + WKCDG+NDCLD SDE C ++T
Sbjct: 868 IQERWKCDGDNDCLDNSDEAPAL---------CHQHT----------------------- 895
Query: 3385 XXXXXXVKYCKDGQKPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNATCA 3564
C + +F+C+N+RCIP +W E C TC
Sbjct: 896 -----------------CPSDRFKCENNRCIPNRWLCDGDNDCGNSEDESNATCSARTCP 938
Query: 3565 ANQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQCVPLRNHX 3744
NQFSCA+GRCIPI W CD D+DC D +DE P QF C NGR C+ N
Sbjct: 939 PNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNGR-CI---NIN 994
Query: 3745 XXXXXXXXXXXXXXXAVTAESCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCT 3924
A + SC+ QFKC +SG CIP W SDE CT
Sbjct: 995 WRCDNDNDCGDNSDEAGCSHSCSSTQFKC-NSGRCIPEHWTCDGDNDCGDYSDETHANCT 1053
Query: 3925 SGRQ-----CSSDQFKCG-NGRCILNNWLCDGENDCGDGSDESS------------ERGC 4050
+ C SD+F+C +G CI W CDG+ DC D SDE S + GC
Sbjct: 1054 NQATRPPGGCHSDEFQCPLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPNVKFGC 1113
Query: 4051 KTSMN------------------------ARKCPFEHVACENDQETCIPLHQLCDGKTHC 4158
K S A C C N+ C+P +LCDGK C
Sbjct: 1114 KDSARCISKAWVCDGDSDCEDNSDEENCEALACRPPSHPCANNTSVCLPPDKLCDGKDDC 1173
Query: 4159 PGGTDEGGRCARDLCSADRAGCSFKCHNSPN-GPICSCPFGEQLVNKTK-CEPENECLDS 4332
G+DEG C D CS + GCS C +P G +CSCP G +L + C+ ++ C
Sbjct: 1174 GDGSDEGELC--DQCSLNNGGCSHNCSVAPGEGIVCSCPLGMELGSDNHTCQIQSYCAKH 1231
Query: 4333 SSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNW 4512
CSQ+C K CSC EG+ L+ D TC+ D K I+ SNR+ I D ++
Sbjct: 1232 LKCSQKCDQNKFSVKCSCYEGWVLEPDGETCRSLDPFKLFIIF-SNRHEIRRIDLHKGDY 1290
Query: 4513 HTFGAIVENAIALAWDSLTDRIYWSDIREKKI----LSANRNGTNATVFIADGLDITEGI 4680
+ N IAL + +YW+D E KI L N T+ V I GL EG+
Sbjct: 1291 SVLVPGLRNTIALDFHLSQSALYWTDAVEDKIYRGKLLDNGALTSFEVVIQYGLATPEGL 1350
Query: 4681 ALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQ 4860
A+DW+ N+YWV+S+L+ IEVA L D RT L+ ++ PR IA+DPR G++FWTDW
Sbjct: 1351 AVDWIAGNIYWVESNLDQIEVAKL-DGTLRTTLLAGDIEHPRAIALDPRDGILFWTDWDA 1409
Query: 4861 N-PCIERASMDGTDRQIIVKTKIYW--PNTIALDYTTDRVYFADSKLDFIDFVNYDGSGR 5031
+ P IE ASM G R+ I + N + +DY R+ + D++ D I YDGSG
Sbjct: 1410 SLPRIEAASMSGAGRRTIHRETGSGGCANGLTVDYLEKRILWIDARSDAIYSARYDGSGH 1469
Query: 5032 TQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVA 5211
+VL +F+ HP A+ ++ +Y++D R L K+ G T ++ +
Sbjct: 1470 MEVLRGHEFLSHPFAVTLYGGEVYWTDWRTNTLAKANKW-TGHNVTVVQRTNTQPFDLQV 1528
Query: 5212 VHPVLQPVIKNNPCSTN----PCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKPFL 5379
HP QP+ N PC N PCSHLCL+N T + CP KL C + K FL
Sbjct: 1529 YHPSRQPMAPN-PCEANGGRGPCSHLCLINYNRTVSWACPHLMKLHKDNTTCYE-FKKFL 1586
Query: 5380 VIIQKTNVFGIEMNSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTL 5559
+ ++ + G+++++ +++ VP + N YDA + ++ +
Sbjct: 1587 LYARQMEIRGVDLDAPYYNY--IISFTVP--DIDNVTVLDYDAREQRVYWSD-------- 1634
Query: 5560 AQITTDSAIYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKIT--QTIEIIRT 5733
AI R+ +NG + S+ +P+ A+ L DW RNL + T + I + R
Sbjct: 1635 ---VRTQAIKRAFINGTGVETVVSADLPN-AHGLAVDWVSRNLFWTSYDTNKKQINVARL 1690
Query: 5734 QGKQYRSVILSNDQSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLV 5913
G +V+ +Q +G ++W D ++ A +DGSN +
Sbjct: 1691 DGSFKNAVVQGLEQPHGLVVHPL-------RGKLYWTDGDN------ISMANMDGSNHTL 1737
Query: 5914 IASNDLAELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGR--QPNGLAFY 6087
+ S + +AID +++Y+ + I+ DG + + + + + LA
Sbjct: 1738 LFSGQKGPVG-LAIDFPESKLYWISSGNHTINRCNLDGSELEVIDTMRSQLGKATALAIM 1796
Query: 6088 GDRLFYADSAFDSIEVATINGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHINNG 6267
GD+L++AD + + S + V ++ +PC +NNG
Sbjct: 1797 GDKLWWADQVSEKMGTCNKADGSGSVVLRNSTTLVMHMKVYDESIQLEHEGTNPCSVNNG 1856
Query: 6268 NCDHICIPLMFAQRTCTCANGY-VKDGQTSCKLFDESFVIVATKTKVIGYPIDETQSKGV 6444
+C +C+P R+C C GY ++ GQ +C+ SF++ + + G P+D K
Sbjct: 1857 DCSQLCLPTSETTRSCMCTAGYSLRSGQQACEGVG-SFLLYSVHEGIRGIPLDPND-KSD 1914
Query: 6445 AMEPIGGLSIT-GVDYDYESKTIYVAEA--SGINKGITAYTIGESSPRAVIRDSIGSLTI 6615
A+ P+ G S+ G+D+ E+ TIY + S I++ T E V+ + IG +
Sbjct: 1915 ALVPVSGTSLAVGIDFHAENDTIYWVDMGLSTISRAKRDQTWRED----VVTNGIGR--V 1968
Query: 6616 KSLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWA 6795
+ +A+DWI N+Y+ + + IEV++L+G++R ++++ + P +I V P YL+W
Sbjct: 1969 EGIAVDWIAGNIYWTDQGFDV--IEVARLNGSFRYVVISQGLDKPRAITVHPEKGYLFWT 2026
Query: 6796 DQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVR-STGG 6972
+ G P I+RS LDG+ R V+V+ I+ P + VD +YW DA+MD I R+ TG
Sbjct: 2027 EWGHYPRIERSRLDGTERVVLVNVSISWPNGISVDYQGGKLYWCDARMDKIERIDLETGE 2086
Query: 6973 TPELV-RSDIASAAGVALHGQNMYWTDN-RLEKLFRATSKPNQTSLLLSPTTVAASLKDI 7146
E+V S+ V++ +YW+D + K N T + T + LKDI
Sbjct: 2087 NREVVLSSNNMDMFSVSVFEDFIYWSDRTHANGSIKRGCKDNATDSVPLRTGIGVQLKDI 2146
Query: 7147 GDVAVFSSNNQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCARGVLK--GRTCEE 7320
VF+ + Q + ++ C + + C QLC G Q C+CA G+L G +C E
Sbjct: 2147 ---KVFNRDRQ-KGTNVCAVANG----GCQQLCLYRGGGQR-ACACAHGMLAEDGASCRE 2197
Query: 7321 PDTYIMFSDGDKIIDVAIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGV 7500
Y+++S+ + + + + + P++ PF + +++ + L Y SP
Sbjct: 2198 YAGYLLYSERTILKSIHLSDERNLNAPVQ-PFEDPEHMKNV---IALAFDYRAGTSPGTP 2253
Query: 7501 NISWFSMNNAENPRLVF--GASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVM--AI 7668
N +FS + N + + G+ + + + + + +Y+T+ + +
Sbjct: 2254 NRIFFSDIHFGNIQQINDDGSGRTTIVENVGSVEGLAYHRGWDTLYWTSYTTSTITRHTV 2313
Query: 7669 DTAG------EHLSTIASGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGG 7830
D E + T++ D A +D C L+FW T+ P I R+ L+G
Sbjct: 2314 DQTRPGAFERETVITMSGDDHPRAFVLDECQNLMFW------TNWNELHPSIMRAALSGA 2367
Query: 7831 SRKVIVSESISLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGYRAK--SLD 8004
+ ++ + I P +A+D R +K+Y++D IE +YDG +R VI L
Sbjct: 2368 NVLTLIEKDIRTPNGLAIDHRAEKLYFSDATLDKIERCEYDGSHRYVILKSEPVHPFGLA 2427
Query: 8005 IWDRWLYMSDPLSNGVFRIDKESGSGLENVVSDRRIPGA-LRVFASESDVRTRNQVCNAL 8181
++ ++ +D + V R +K GS ++ + D IP + + A +D N+
Sbjct: 2428 VYGEHIFWTDWVRRAVQRANKYVGSDMKLLRVD--IPQQPMGIIAVANDT-------NSC 2478
Query: 8182 TSQLCKTDNGGCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSE 8361
C+ +NGGC LC + V CSC G+ R NS
Sbjct: 2479 ELSPCRINNGGCQDLCLLTHQ------GHVNCSCRG--------GRILQEDFTCRAVNSS 2524
Query: 8362 PAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCI 8541
C F+C +G CI TCD C D SDE P+YCN+R C + + C N RC+
Sbjct: 2525 ----CRAQDEFECANGECISFSLTCDGVSHCKDKSDEKPSYCNSRRCKKTFRQCNNGRCV 2580
Query: 8542 DSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDE 8721
+ CN +D CGDGSDE+ C + AC G F C +G CI + C+ DC D SDE
Sbjct: 2581 SNMLWCNGVDYCGDGSDEIPC-NKTACGVGEFRCRDGSCIGNSSRCNQFVDCED--ASDE 2637
Query: 8722 ---SLATCPG-LPIDCRGVKVR-CPNTNICIQPADLCDGYDDCGDKADENQLFCMNQ-QC 8883
S C + +GV + C T++C P+ +CDG +DCGD +DE + + +C
Sbjct: 2638 MNCSATDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDERDCPGVKRPRC 2697
Query: 8884 AQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCIS 9063
+Y CPSGRCIP +W CD ++DC +G DETH N K C + F+C N +CIS
Sbjct: 2698 PLNYFACPSGRCIPMSWTCDKEDDCENGEDETHCN-------KFC-SEAQFECQNHRCIS 2749
Query: 9064 RAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVT 9243
+ ++ + C +TC F C + C+P WLCDGD
Sbjct: 2750 KQWLCDGSDDCGDGSDEAAH--CEGKTCGPSSFSCPGT-------HVCVPERWLCDGDKD 2800
Query: 9244 CAGGEDESTELCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQ 9423
C G DES C+ EF C N+ CI + CD D DC DGSDE C Y +C
Sbjct: 2801 CTDGADESVTAGCLYNSTCDDREFMCQNRLCIPKHFVCDHDRDCADGSDESPECEYPTCG 2860
Query: 9424 PDFFQCANHKCVPN-SWKCDGNDDCEDGSDEKDCPKNSASAQKASKCS-NGQFQCTSGEC 9597
P+ F+CAN +C+ + W+CDG +DC D SDE PKN KC+ + QF C+SG C
Sbjct: 2861 PNEFRCANGRCLSSRQWECDGENDCHDHSDE--APKNPHCTSPEHKCNASSQFLCSSGRC 2918
Query: 9598 IDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDIS 9777
+ +A +C+ DC D SDE C ++EC + C Q C D+KIG+KC C GF +
Sbjct: 2919 VAEALLCNGQDDCGDGSDERG-CHVNECLSRKLSGCSQDCEDLKIGFKCRCRPGFRLK-D 2976
Query: 9778 DQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQ-LSSDDHSCKRTEMEPEPFFLL 9954
D ++C +++EC CSQ C + GSYKC CV+GY D HSCK E EPF +
Sbjct: 2977 DGRTCADLDECSTTFP-CSQLCINTHGSYKCLCVEGYAPRGGDPHSCKAVTDE-EPFLIF 3034
Query: 9955 ANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAY---LIDQGKLRLLRVDLDEMD 10125
AN++Y+RK+++DG+ Y L QG +N V+L D E+ Y + QG + + R+ L+
Sbjct: 3035 ANRYYLRKLNLDGSNYTLLKQGLNNAVALAFDYREQMIYWTGVTTQGSM-IRRMHLNG-- 3091
Query: 10126 SPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQP 10305
S+ + + R + +G+AVDWVG LY ++ +I V +L+G + L+ +++P
Sbjct: 3092 ---SNVQVLHRTGLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVSSGLREP 3148
Query: 10306 KAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDR 10485
+A+VV GYL++T+W IGRI +DGS + + + WPN + +DY ++R
Sbjct: 3149 RALVVDVQNGYLYWTDWGDHSLIGRIGMDGSGRSI-----IVDTKITWPNGLTVDYVTER 3203
Query: 10486 LFWGDAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTG 10665
++W DA + I F DG+ R + +Q H+ ++ +F+DY+YW DW + + R K TG
Sbjct: 3204 IYWADAREDYIEFASLDGSNRHVVLSQDIPHIFALTLFEDYVYWTDWETKSINRAHKTTG 3263
Query: 10666 KNETILKKTVQLPNDLRIVHPMRQPAYPN-PCGDNNGGCSHLCLIGAGGNGYTCSCPDQF 10842
N+T+L T+ P DL + H +RQP PN PC NNGGCS+LCL+ GG G+ C+CP F
Sbjct: 3264 ANKTLLISTLHRPMDLHVFHALRQPDVPNHPCKVNNGGCSNLCLLSPGG-GHKCACPTNF 3322
Query: 10843 VLLSDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVG 11022
L D +TC NCT QF C D KCIP W CD E DC D SDEP + C + C G
Sbjct: 3323 YLGGDGRTCVSNCTASQFVCKND--KCIPFWWKCDTEDDCGDHSDEPPD--CPEFKCRPG 3378
Query: 11023 EFQCTNHNCTRPFQIXXXXXXXXXXXXEQNCD-KACDPWMFKCAATGRCIPRRFTXXXXX 11199
+FQC+ CT P I E NCD C P FKC T RCIP F
Sbjct: 3379 QFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQD 3438
Query: 11200 XXXXRSDEADTLCMSAERNCTAEEFRCN-NNKCIAKAWRXXXXXXXXXXXXETPECAQIE 11376
DE D E C +F+C+ +CI + W E C Q+
Sbjct: 3439 NCGDGEDERD----CPEVTCAPNQFQCSITKRCIPRVWVCDRDNHCVDGSDEPANCTQMT 3494
Query: 11377 CKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCP--TCDDVGEFRCATSGKCIPR 11550
C RC S RCIP C+G+DDC D SDE K+ C TC+ +FRC + +C+P
Sbjct: 3495 CGVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPY-QFRC-KNNRCVPG 3552
Query: 11551 RWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDES 11730
RW CD +NDCGDNSDE SC T RPCSESEF C +G+CI G CDG C+DG DE
Sbjct: 3553 RWQCDYDNDCGDNSDE--ESC--TPRPCSESEFFCANGRCIAGRWKCDGDHDCADGSDEK 3608
Query: 11731 QCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFECANSV 11910
CT RC QC G CI CD DC + +DE C RTC EF+C N++
Sbjct: 3609 DCT-PRCDMDQFQCKSGHCIPLRWPCDADADCMDGSDEEAC-GTGVRTCPLDEFQCNNTL 3666
Query: 11911 CIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPN 12090
C P + SDE EC C P FRC + R+CL I + C+G ++CG
Sbjct: 3667 CKPLAWKCDGEDDCGDNSDENPEECARFICPPNRPFRCKNDRVCLWIGRQCDGVDNCG-- 3724
Query: 12091 DFSDEHLSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKT 12270
D +DE + +F C N +C++ ++ C+ DDCGD SDE CS T
Sbjct: 3725 DGTDEEDCEPPTAQNPHCKDKKEFLCRNQRCLSSSLRCNMFDDCGDGSDEEDCSIDPKLT 3784
Query: 12271 SCEAFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTK 12450
SC + G + C YC CR GF P P C DI+EC TC+QL K
Sbjct: 3785 SCATNASMCGDEARCVRTEKAAYCACRSGFHTVPGQP-GCQDINECLRFGTCSQLWNKPK 3843
Query: 12451 GSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGSGTNRHXXXXX 12630
G +LC C ++ T C+A+G V+ ADD+ ++ G + +
Sbjct: 3844 GGHLCSCARNF-------MKTHNTCKAEGSEYQVLYIADDNEIRSLFPGHPHSAYEQTFQ 3896
Query: 12631 XXXXXXXXXXXXXPRKELMYWIDGSERTI-YRS---AIANGNQSHEGQKLDVDFAAMGV- 12795
+ +YW + TI YRS A + +++D + +
Sbjct: 3897 GDESVRIDAMDVHVKAGRVYWTNWHTGTISYRSLPPAAPPTTSNRHRRQIDRGVTHLNIS 3956
Query: 12796 ---VPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYL 12966
+P IA+D+ GN++ ++ I V G
Sbjct: 3957 GLKMPRGIAIDWVAGNVYWTDSGRDV-----------------------IEVAQMKGENR 3993
Query: 12967 KKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAI 13146
K +++G + +P A++ P G + +SD G H KIE A MDGT R+ +V+D + PT +A+
Sbjct: 3994 KTLISGMIDEPHAIVVDPLRGTMYWSDWGNHPKIETAAMDGTLRETLVQDNIQWPTGLAV 4053
Query: 13147 DEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRH---IPYAVDVFENHIYWLSRESKT 13317
D R+YW D K + ++ ++G++ + P+++DVFE++IY ++ +
Sbjct: 4054 DY-HNERLYWADAKLSVIGSIRLNGTDPIVAADSKRGLSHPFSIDVFEDYIYGVTYINNR 4112
Query: 13318 LYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTGFA 13497
++ KFG + L L H V + + C+R +C LC+ PS G
Sbjct: 4113 VFKIHKFGHSPLYNLTGGL--SHASDVVLYHQHKQPEVTNPCDRKKCEWLCLLSPS-GPV 4169
Query: 13498 CLCPDGIVPQLD-GSCATQHVEALTMPKQC--------KCTNGGKCRLDG----SCECTS 13638
C CP+G +LD G+C V + T P +C NGG C L+ C C
Sbjct: 4170 CTCPNG--KRLDNGTCVP--VPSPTPPPDAPRPGTCTLQCFNGGSCFLNARRQPKCRCQP 4225
Query: 13639 DFEGDQCE 13662
+ GD+CE
Sbjct: 4226 RYTGDKCE 4233
Score = 360 bits (925), Expect = 4e-97
Identities = 285/1027 (27%), Positives = 442/1027 (42%), Gaps = 27/1027 (2%)
Frame = +1
Query: 130 ASVNTASSVCNENDFRCNDGKCIRTEWX-XXXXXXXXXXXXXXXXPHPGCKSDQWQCDTY 306
++ ++ C N F C G+CI W +P C + +
Sbjct: 928 SNATCSARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPTC----FPLTQF 983
Query: 307 TWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGK 486
T ++ CI RCDN DC D SDE C S CSS F C GR C CDG
Sbjct: 984 TCNNGRCININWRCDNDNDCGDNSDEAGCSHS---CSSTQ-FKCNSGR-CIPEHWTCDGD 1038
Query: 487 YDCRDLSDEKD-SCSRNHT----ACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDT 651
DC D SDE +C+ T C +F+C CI W CDG DC D SDE +
Sbjct: 1039 NDCGDYSDETHANCTNQATRPPGGCHSDEFQCPLDGLCIPLRWRCDGDTDCMDSSDE-KS 1097
Query: 652 CE--FKKCTAN-EFQCKNK-RCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCP-GT 816
CE C N +F CK+ RC + + CD DC DNSDE+ C C P C T
Sbjct: 1098 CEGVTHVCDPNVKFGCKDSARCISKAWVCDGDSDCEDNSDEENCEALACRPPSHPCANNT 1157
Query: 817 GHCIDQLKLCDGSKDCADGADE-QQCSQNLCPSLGCQAGCHPSP-HGGECTCPSGYKLDD 990
C+ KLCDG DC DG+DE + C Q + GC C +P G C+CP G +L
Sbjct: 1158 SVCLPPDKLCDGKDDCGDGSDEGELCDQCSLNNGGCSHNCSVAPGEGIVCSCPLGMELGS 1217
Query: 991 RFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSN 1170
H TC + CA+ C Q C ++ CSC + + L+ D T R
Sbjct: 1218 DNH-TCQIQSYCAKHLKCSQKCDQNKFSVKCSCY-EGWVLE------PDGETCR------ 1263
Query: 1171 NADKMKLFV--ARREGLYRLNPKNPDEEVKKLASG-EFIYGIDFDYGDRKIFWTDRLAHS 1341
+ D KLF+ + R + R++ D V L G +DF ++WTD +
Sbjct: 1264 SLDPFKLFIIFSNRHEIRRIDLHKGDYSV--LVPGLRNTIALDFHLSQSALYWTDAVEDK 1321
Query: 1342 AFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTV 1521
+ + D G ++ + + L P LAVDWI +Y +ES +I+V+ DG RT
Sbjct: 1322 IYRGKLLDNGALTSFEVVIQYGLATPEGLAVDWIAGNIYWVESNLDQIEVAKLDGTLRTT 1381
Query: 1522 LLADGLTLPLDIALDPLRGEMFFT----NQLKLEAAAMDGTNRRTLVNTHTHQ---VSGI 1680
LLA + P IALDP G +F+T + ++EAA+M G RRT ++ T +G+
Sbjct: 1382 LLAGDIEHPRAIALDPRDGILFWTDWDASLPRIEAASMSGAGRRT-IHRETGSGGCANGL 1440
Query: 1681 VVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRL 1860
VD KR+ W+D + D + S Y G+ V +G + HPF + L+ +YWTDW
Sbjct: 1441 TVDYLEKRILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYGGEVYWTDWRTN 1500
Query: 1861 GVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEG 2040
+ + K+ + T N P + YHP QP + C A PC++
Sbjct: 1501 TLAKANKWTGHNVTVVQRT--NTQPFDLQVYHPSRQP-MAPNPCEANGGRGPCSH----- 1552
Query: 2041 MCILSKDNGGFGVGYKCACPIGQKL-VNGKRCIDSIDYLLFSSNKIVRGIFPEINEKALA 2217
+C+++ + ACP KL + C + +LL++ +RG+ + A
Sbjct: 1553 LCLIN-----YNRTVSWACPHLMKLHKDNTTCYEFKKFLLYARQMEIRGVDLD------A 1601
Query: 2218 EAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGL 2397
I + I ++ D +++D+ I R +G G V+
Sbjct: 1602 PYYNYIISFTVPDIDNVTVLDYDAREQRVYWSDVRTQAIKRAFINGTGVETVVSADLPNA 1661
Query: 2398 FSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKG 2577
++ DW+S+ L++ N ++ + D + ++ L P +VVHP +G
Sbjct: 1662 HGLAVDWVSRNLFWTSYDTNKKQI------NVARLDGSFKNAVVQGLEQPHGLVVHPLRG 1715
Query: 2578 LLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMD 2757
L++ + I ++DG N ++ + G P +AIDF E++L W + TI+ +
Sbjct: 1716 KLYWTDGDN---ISMANMDGSNHTLLFSGQKG-PVGLAIDFPESKLYWISSGNHTINRCN 1771
Query: 2758 FDGKNVVKLDIDNP---IPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADE 2928
DG + +D A+ IM + +++ Q + +K +G GS ++R
Sbjct: 1772 LDGSELEVIDTMRSQLGKATALAIMGDKLWWADQVSEKMGTCNKADGSGSVVLRN---ST 1828
Query: 2929 RSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINK 3108
+ +K Q + + C+QLC T +E C C G+ + +
Sbjct: 1829 TLVMHMKVYDESIQLEHEGTNPCSVNNGDCSQLCLPT------SETTRSCMCTAGYSL-R 1881
Query: 3109 ENNHSCQ 3129
+C+
Sbjct: 1882 SGQQACE 1888
Score = 322 bits (824), Expect = 2e-85
Identities = 214/683 (31%), Positives = 309/683 (44%), Gaps = 21/683 (3%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAE 336
C N F C G+CI W + C Q++C + CI++
Sbjct: 2697 CPLNYFACPSGRCIPMSWTCDKEDDCENGEDETHC-NKFCSEAQFECQNHR-----CISK 2750
Query: 337 YQRCDNITDCADGSDEK-DCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDE 513
CD DC DGSDE C T SS F C C CDG DC D +DE
Sbjct: 2751 QWLCDGSDDCGDGSDEAAHCEGKTCGPSS---FSCPGTHVCVPERWLCDGDKDCTDGADE 2807
Query: 514 KDS--CSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQ 687
+ C N T C +F C ++ CI K +VCD +DCADGSDE CE+ C NEF+
Sbjct: 2808 SVTAGCLYNST-CDDREFMCQNRL-CIPKHFVCDHDRDCADGSDESPECEYPTCGPNEFR 2865
Query: 688 CKNKRC-QPRKFRCDYYDDCGDNSDE----DEC--GEYRCPPGKWNCPGTGHCIDQLKLC 846
C N RC R++ CD +DC D+SDE C E++C +G C+ + LC
Sbjct: 2866 CANGRCLSSRQWECDGENDCHDHSDEAPKNPHCTSPEHKCNASSQFLCSSGRCVAEALLC 2925
Query: 847 DGSKDCADGADEQQCSQNLCPS---LGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDI 1017
+G DC DG+DE+ C N C S GC C G +C C G++L D RTC+D+
Sbjct: 2926 NGQDDCGDGSDERGCHVNECLSRKLSGCSQDCEDLKIGFKCRCRPGFRLKDD-GRTCADL 2984
Query: 1018 NECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRG----YCVSNNADKM 1185
+EC+ C QLC N + C C+ + RG C + ++
Sbjct: 2985 DECSTTFPCSQLCINTHGSYKCLCV--------------EGYAPRGGDPHSCKAVTDEEP 3030
Query: 1186 KLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDD 1365
L A R L +LN + + K + + FDY ++ I+WT + +
Sbjct: 3031 FLIFANRYYLRKLNLDGSNYTLLKQGLNNAV-ALAFDYREQMIYWTGVTTQGSMIRRMHL 3089
Query: 1366 EGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTL 1545
G S ++ L L P LAVDW+ LY + G I+VS +G RTVL++ GL
Sbjct: 3090 NG--SNVQVLHRTGLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVSSGLRE 3147
Query: 1546 PLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWV 1716
P + +D G +++T + + MDG+ R +V+T +G+ VD +R+YW
Sbjct: 3148 PRALVVDVQNGYLYWTDWGDHSLIGRIGMDGSGRSIIVDTKITWPNGLTVDYVTERIYWA 3207
Query: 1717 DPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFGSDT 1896
D + D +E G++R +V +PH F L LF+ Y+YWTDW + + K
Sbjct: 3208 DAREDYIEFASLDGSNRHVVLS--QDIPHIFALTLFEDYVYWTDWETKSINRAHKTTGAN 3265
Query: 1897 KLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFG 2076
K L +T + PM + +H + QP C N C +C+LS G
Sbjct: 3266 KTLLISTLHR--PMDLHVFHALRQPDVPNHPC-------KVNNGGCSNLCLLSP-----G 3311
Query: 2077 VGYKCACPIGQKL-VNGKRCIDS 2142
G+KCACP L +G+ C+ +
Sbjct: 3312 GGHKCACPTNFYLGGDGRTCVSN 3334
Score = 174 bits (442), Expect = 4e-41
Identities = 96/278 (34%), Positives = 133/278 (47%), Gaps = 5/278 (1%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAE 336
C F+C+ G C + C Q++C ++ CI
Sbjct: 3375 CRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCT----NTNRCIPG 3430
Query: 337 YQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEK 516
RC+ +C DG DE+DCP T + N F C+ ++C CD C D SDE
Sbjct: 3431 IFRCNGQDNCGDGEDERDCPEVTC---APNQFQCSITKRCIPRVWVCDRDNHCVDGSDEP 3487
Query: 517 DSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEP-DTCEFKKCTANEFQCK 693
+C++ C +FRC D +CI W CDG DC DGSDEP + C+ + C +F+CK
Sbjct: 3488 ANCTQ--MTCGVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCK 3545
Query: 694 NKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADG 873
N RC P +++CDY +DCGDNSDE+ C C ++ C G CI CDG DCADG
Sbjct: 3546 NNRCVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFFC-ANGRCIAGRWKCDGDHDCADG 3604
Query: 874 ADEQQCSQNL-CPSLGCQAG-CHPS--PHGGECTCPSG 975
+DE+ C+ C++G C P P + C G
Sbjct: 3605 SDEKDCTPRCDMDQFQCKSGHCIPLRWPCDADADCMDG 3642
Score = 144 bits (364), Expect = 5e-32
Identities = 94/290 (32%), Positives = 123/290 (42%), Gaps = 45/290 (15%)
Frame = +1
Query: 148 SSVCNENDFRCNDGKCI-----------------------------RTEWXXXXXXXXXX 240
SS +++F C +G+CI +T
Sbjct: 2523 SSCRAQDEFECANGECISFSLTCDGVSHCKDKSDEKPSYCNSRRCKKTFRQCNNGRCVSN 2582
Query: 241 XXXXXXXPHPGCKSDQWQCD-------TYTWHSVSCIAEYQRCDNITDCADGSDEKDCPA 399
+ G SD+ C+ + SCI RC+ DC D SDE +C
Sbjct: 2583 MLWCNGVDYCGDGSDEIPCNKTACGVGEFRCRDGSCIGNSSRCNQFVDCEDASDEMNC-- 2640
Query: 400 STVDCSS------QNVFM--CADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQY 555
S DCSS + V C C+ S CDG DC D SDE+D C
Sbjct: 2641 SATDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDERDCPGVKRPRCPLN 2700
Query: 556 QFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYY 735
F C +CI SW CD DC +G DE +F C+ +F+C+N RC +++ CD
Sbjct: 2701 YFAC-PSGRCIPMSWTCDKEDDCENGEDETHCNKF--CSEAQFECQNHRCISKQWLCDGS 2757
Query: 736 DDCGDNSDE-DECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADE 882
DDCGD SDE C C P ++CPGT C+ + LCDG KDC DGADE
Sbjct: 2758 DDCGDGSDEAAHCEGKTCGPSSFSCPGTHVCVPERWLCDGDKDCTDGADE 2807
Score = 140 bits (353), Expect = 9e-31
Identities = 98/323 (30%), Positives = 136/323 (41%), Gaps = 47/323 (14%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDE-KDCP----------ASTVDCSS 420
C + Q+ C + CI + +CD DC D SDE DCP ST C++
Sbjct: 3335 CTASQFVCK-----NDKCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQFQCSTGICTN 3389
Query: 421 --------------------------QNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDS 522
+ F C + +C +C+G+ +C D DE+D
Sbjct: 3390 PAFICDGDNDCQDNSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDC 3449
Query: 523 CSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNK- 699
C QF+C+ +CI + WVCD C DGSDEP C C +EF+CK+
Sbjct: 3450 ---PEVTCAPNQFQCSITKRCIPRVWVCDRDNHCVDGSDEPANCTQMTCGVDEFRCKDSG 3506
Query: 700 RCQPRKFRCDYYDDCGDNSDE--DECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADG 873
RC P +++CD DDCGD SDE +EC E C P ++ C C+ CD DC D
Sbjct: 3507 RCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCK-NNRCVPGRWQCDYDNDCGDN 3565
Query: 874 ADEQQC-------SQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAE 1032
+DE+ C S+ C + C AG G+ C G D R D +C +
Sbjct: 3566 SDEESCTPRPCSESEFFCANGRCIAGRWKC--DGDHDCADGSDEKDCTPRCDMDQFQC-K 3622
Query: 1033 FGYCDQLCANHRPGFTCSCLGDC 1101
G+C L + C DC
Sbjct: 3623 SGHCIPL------RWPCDADADC 3639
Score = 132 bits (333), Expect = 2e-28
Identities = 84/242 (34%), Positives = 106/242 (43%), Gaps = 14/242 (5%)
Frame = +1
Query: 430 FMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCD 609
F CA+ R C KCDG DC D SDE + HT C +F+C + +CI W+CD
Sbjct: 860 FACANNR-CIQERWKCDGDNDCLDNSDEAPALCHQHT-CPSDRFKC-ENNRCIPNRWLCD 916
Query: 610 GSKDCADGSDEPD-TCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDED-ECGEYR 783
G DC + DE + TC + C N+F C + RC P + CD DDCGD SDE C
Sbjct: 917 GDNDCGNSEDESNATCSARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPT 976
Query: 784 CPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECT 963
C P G CI+ CD DC D +DE AGC S +
Sbjct: 977 CFPLTQFTCNNGRCININWRCDNDNDCGDNSDE--------------AGCSHSCSSTQFK 1022
Query: 964 CPSGYKLDDRFHRTCSDINECAEFGYCDQLCAN------------HRPGFTCSCLGDCFT 1107
C SG + + H TC N+C + Y D+ AN H F C G C
Sbjct: 1023 CNSGRCIPE--HWTCDGDNDCGD--YSDETHANCTNQATRPPGGCHSDEFQCPLDGLCIP 1078
Query: 1108 LQ 1113
L+
Sbjct: 1079 LR 1080
Score = 106 bits (265), Expect = 1e-20
Identities = 151/619 (24%), Positives = 228/619 (36%), Gaps = 29/619 (4%)
Frame = +1
Query: 7198 CQ-ITDNLRKSPCTQLCFATPGTQTPTCSCARGVLKGR-TC--EEPDTYIMFSDGDKIID 7365
CQ I + LR C+QL G CSCAR +K TC E + +++ D I
Sbjct: 3823 CQDINECLRFGTCSQLWNKPKGGHL--CSCARNFMKTHNTCKAEGSEYQVLYIADDNEIR 3880
Query: 7366 VAIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAENPRL 7545
++ E + DV V RVY+ G IS+ S+ A P
Sbjct: 3881 SLFPGHPHSAYEQTFQGDESVRIDAMDVHVKAGRVYWT-NWHTGT-ISYRSLPPAAPP-- 3936
Query: 7546 VFGASKQPHAKEIR------HISDMKL------DWLTQKIYFTTGRGGKVMAIDTAGEHL 7689
+ H ++I +IS +K+ DW+ +Y+T + GE+
Sbjct: 3937 ---TTSNRHRRQIDRGVTHLNISGLKMPRGIAIDWVAGNVYWTDSGRDVIEVAQMKGENR 3993
Query: 7690 STIASG--DWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESIS 7863
T+ SG D +A+ +DP G ++WSD G P+IE + + G R+ +V ++I
Sbjct: 3994 KTLISGMIDEPHAIVVDPLRGTMYWSDWGN-------HPKIETAAMDGTLRETLVQDNIQ 4046
Query: 7864 LPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGYRAKS----LDIWDRWLYMS 8031
P +AVD+ N+++YWAD I +G + V A R S +D+++ ++Y
Sbjct: 4047 WPTGLAVDYHNERLYWADAKLSVIGSIRLNGTDPIVAADSKRGLSHPFSIDVFEDYIYGV 4106
Query: 8032 DPLSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNG 8211
++N VF+I K S L N+ + SDV +Q + C D
Sbjct: 4107 TYINNRVFKIHKFGHSPLYNLTGG---------LSHASDVVLYHQHKQPEVTNPC--DRK 4155
Query: 8212 GCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSEPAKECLP-PY 8388
C+ LC L+ S C+C + L D T CV S + P P
Sbjct: 4156 KCEWLCL-------LSPSGPVCTCPNGKRL------DNGT-CVPVPSPTPPPDAPRPGTC 4201
Query: 8389 NFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHI 8568
QC +G L A K C P Y + C +C +
Sbjct: 4202 TLQCFNGGSCFLNARRQPKCRC------QPRYTGDK--------CELDQCWEYCHNGGTC 4247
Query: 8569 DDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPGLP 8748
G CP+ + T G+C N ++ C Q + PG
Sbjct: 4248 AASPSGMPTCRCPTGFTGPKCTAQVCAGYCSN-------NSTCTVNQGNQPQCRCLPGFL 4300
Query: 8749 ID------CRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPS 8910
D C G C N C AD G C C +C+ RC
Sbjct: 4301 GDRCQYRQCSGF---CENFGTCQMAAD---GSRQCRCTVYFEGPRCEVNKCS----RCLQ 4350
Query: 8911 GRCIPETWQCDGDNDCSDG 8967
G C+ D +C+DG
Sbjct: 4351 GACVVNKQTGDVTCNCTDG 4369
Score = 106 bits (264), Expect = 2e-20
Identities = 59/172 (34%), Positives = 78/172 (45%)
Frame = +1
Query: 391 CPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCA 570
C + CS+ + G +C C + L + +C N TA QF C
Sbjct: 3295 CKVNNGGCSNLCLLSPGGGHKC-----ACPTNFY---LGGDGRTCVSNCTAS---QFVCK 3343
Query: 571 DKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGD 750
+ +CI W CD DC D SDEP C KC +FQC C F CD +DC D
Sbjct: 3344 ND-KCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQFQCSTGICTNPAFICDGDNDCQD 3402
Query: 751 NSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLC 906
NSDE C + C P ++ C T CI + C+G +C DG DE+ C + C
Sbjct: 3403 NSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTC 3454
Score = 105 bits (261), Expect = 4e-20
Identities = 87/282 (30%), Positives = 118/282 (40%), Gaps = 23/282 (8%)
Frame = +1
Query: 325 CIAEYQRCDNITDCADG---SDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDC 495
C+ +Q N + C G ++ C A C +Q+ F CA+G +C S CDG C
Sbjct: 2494 CLLTHQGHVNCS-CRGGRILQEDFTCRAVNSSCRAQDEFECANG-ECISFSLTCDGVSHC 2551
Query: 496 RDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTA 675
+D SDEK S N C + FR + +C+ C+G C DGSDE C C
Sbjct: 2552 KDKSDEKPSYC-NSRRC-KKTFRQCNNGRCVSNMLWCNGVDYCGDGSDE-IPCNKTACGV 2608
Query: 676 NEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPG---------KWNCPGTGHCI 828
EF+C++ C RC+ + DC D SDE C C C T C
Sbjct: 2609 GEFRCRDGSCIGNSSRCNQFVDCEDASDEMNCSATDCSSYFRLGVKGVLFQPCERTSLCY 2668
Query: 829 DQLKLCDGSKDCADGADEQQC---SQNLCP--SLGCQAG-CHPSPH--GGECTCPSGYKL 984
+CDG+ DC D +DE+ C + CP C +G C P E C +G
Sbjct: 2669 APSWVCDGANDCGDYSDERDCPGVKRPRCPLNYFACPSGRCIPMSWTCDKEDDCENG--- 2725
Query: 985 DDRFHRTCSDINECAEFGYCDQLCANHR---PGFTCSCLGDC 1101
+D H C+ A+F C NHR + C DC
Sbjct: 2726 EDETH--CNKFCSEAQFE-----CQNHRCISKQWLCDGSDDC 2760
Score = 82.8 bits (203), Expect = 2e-13
Identities = 62/242 (25%), Positives = 93/242 (37%), Gaps = 20/242 (8%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEW--XXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCI 330
C+ + F+C G CI W C D++QC+ + C
Sbjct: 3614 CDMDQFQCKSGHCIPLRWPCDADADCMDGSDEEACGTGVRTCPLDEFQCN-----NTLCK 3668
Query: 331 AEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSD 510
+CD DC D SDE + C F C + R C + ++CDG +C D +D
Sbjct: 3669 PLAWKCDGEDDCGDNSDENPEECARFICPPNRPFRCKNDRVCLWIGRQCDGVDNCGDGTD 3728
Query: 511 EKD---SCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTC---EFKKCT 672
E+D ++N + +F C ++ +C+ S C+ DC DGSDE D + C
Sbjct: 3729 EEDCEPPTAQNPHCKDKKEFLCRNQ-RCLSSSLRCNMFDDCGDGSDEEDCSIDPKLTSCA 3787
Query: 673 ANEFQCKNKRCQPRKFRCDYYDDCGDNS------------DEDECGEYRCPPGKWNCPGT 816
N C ++ R + Y C S D +EC + WN P
Sbjct: 3788 TNASMCGDEARCVRTEKAAY---CACRSGFHTVPGQPGCQDINECLRFGTCSQLWNKPKG 3844
Query: 817 GH 822
GH
Sbjct: 3845 GH 3846
Score = 67.4 bits (163), Expect = 1e-08
Identities = 43/129 (33%), Positives = 56/129 (43%), Gaps = 19/129 (14%)
Frame = +1
Query: 610 GSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKF------------RCDYYDDCGDN 753
GS+ CA D+ + C AN +CQP +F +CD +DC DN
Sbjct: 824 GSRQCACAEDQVLDTDGVTCLANPSYVPPPQCQPGQFACANNRCIQERWKCDGDNDCLDN 883
Query: 754 SDEDE--CGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQ--CSQNLCP--SL 915
SDE C ++ CP ++ C CI LCDG DC + DE CS CP
Sbjct: 884 SDEAPALCHQHTCPSDRFKCE-NNRCIPNRWLCDGDNDCGNSEDESNATCSARTCPPNQF 942
Query: 916 GCQAG-CHP 939
C +G C P
Sbjct: 943 SCASGRCIP 951
Score = 47.0 bits (110), Expect = 0.014
Identities = 31/102 (30%), Positives = 42/102 (40%), Gaps = 10/102 (9%)
Frame = +1
Query: 8746 PIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMN---QQCAQHYVRC-PSG 8913
P C + C + CI CDG DC D +DE C Q+C + C +
Sbjct: 25 PKTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEHSCLGTE 84
Query: 8914 RCIPETWQCDGDNDCSDGWD------ETHTNCTDTAGKKICV 9021
C+P + C+G DC DG D E NC+ + CV
Sbjct: 85 LCVPMSRLCNGIQDCMDGSDEGAHCRELRANCSRMGCQHHCV 126
Score = 45.4 bits (106), Expect = 0.040
Identities = 62/230 (26%), Positives = 86/230 (36%), Gaps = 29/230 (12%)
Frame = +1
Query: 9142 TCTDQEFH---CTSNAKLAQPKYECIPR----------AW-LCDGDVTCAGGEDESTELC 9279
TCT Q F+ C NA+ QPK C PR W C TCA C
Sbjct: 4200 TCTLQCFNGGSCFLNAR-RQPKCRCQPRYTGDKCELDQCWEYCHNGGTCAASPS-GMPTC 4257
Query: 9280 KTEKKECNKGEF--RCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFF--QCAN 9447
+ C G +C+ Q C C ++ C C C P F +C
Sbjct: 4258 R-----CPTGFTGPKCTAQVC---AGYCSNNSTCTVNQGNQPQCR---CLPGFLGDRCQY 4306
Query: 9448 HKCVPNSWKCDGNDDCE---DGSDEKDCPKNSASAQ-KASKCSNGQFQCTSGECIDDAKV 9615
+C S C+ C+ DGS + C + + +KCS +C G C+ + +
Sbjct: 4307 RQC---SGFCENFGTCQMAADGSRQCRCTVYFEGPRCEVNKCS----RCLQGACVVNKQT 4359
Query: 9616 CDRNFDCTD-RSDESSLCFIDECS------LAEKPLCEQKCMDMKIGYKC 9744
D +CTD R S L ID CS + K + E +C G +C
Sbjct: 4360 GDVTCNCTDGRVAPSCLTCIDHCSNGGSCTMNSKMMPECQCPPHMTGPRC 4409
>gi|34865759|ref|XP_243524.2| similar to lipoprotein receptor-related
protein [Rattus norvegicus]
Length = 4662
Score = 1992 bits (5161), Expect = 0.0
Identities = 1391/4580 (30%), Positives = 2102/4580 (45%), Gaps = 246/4580 (5%)
Frame = +1
Query: 661 KKCTANEFQCKNK-RCQPRKFRCDYYDDCGDNSDE-----DECGEYRCPPGKWNCPGTGH 822
K C+ +F C+++ C + +RCD DC D SDE + RCPP + +C GT
Sbjct: 26 KTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEHSCLGTEL 85
Query: 823 CIDQLKLCDGSKDCADGADEQQCSQNL---CPSLGCQAGCHPSPHGGECTCPSGYKLDDR 993
C+ +LC+G +DC DG+DE + L C +GCQ C P+P G C C + ++L
Sbjct: 86 CVPMSRLCNGIQDCMDGSDEGAHCRELRVNCSRMGCQHHCVPTPSGPTCYCNNSFQLQAD 145
Query: 994 FHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNN 1173
+TC D +EC+ +G C QLC N FTC C+ + + LQ DN + C + N
Sbjct: 146 -GKTCKDFDECSVYGTCSQLCTNTDGSFTCGCV-EGYLLQ------PDNRS----CKAKN 193
Query: 1174 ADKMK---LFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSA 1344
+ L +A + + S +DF Y + + W
Sbjct: 194 EPVDRPPVLLIANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWVH------ 247
Query: 1345 FSADVDDEGEISQIKKL---SLK------------SLVYPRCLAVDWITNTLYIIESGSR 1479
V D +Q+K SLK SL + +A+DW+T Y ++
Sbjct: 248 ----VGDSAAQTQLKCARMPSLKGFVDEHTINISLSLHHVEQMAIDWLTGNFYFVDDIDD 303
Query: 1480 RIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTNQ---LKLEAAAMDGTNRRTLV 1650
RI V + +G+ LL L P IALDP G++FFT+ K+E MDG NR LV
Sbjct: 304 RIFVCNRNGDTCVTLLDLELYNPKGIALDPAMGKVFFTDYGQIPKVERCDMDGQNRTKLV 363
Query: 1651 NTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQ 1830
++ GI +D+ ++ VYW D +D +E +DY+G R+ + QG+ ++ H +GL +F+
Sbjct: 364 DSKIVFPHGITLDLVSRLVYWADAYLDYIEVVDYEGKGRQTIIQGI-LIEHLYGLTVFEN 422
Query: 1831 YLYWTD------WTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSEC 1992
YLY T+ + VI+V +F S + + + + YH QP C
Sbjct: 423 YLYATNSDNANTQQKTSVIRVNRFNSTEYQVVTRVDKGG---ALHIYHQRRQPRVRSHAC 479
Query: 1993 LAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKL-VNGKRCIDSIDYLLFSSN 2169
+ P C +C+L+ + C C G L +GK C L
Sbjct: 480 ENDQYGKP---GGCSDICLLANSHKA----RTCRCRSGFSLGSDGKSCKKPEHELFLVYG 532
Query: 2170 K----IVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFF--YADIMDNT 2331
K I+RG+ ++ K E ++PI + R D H + F +AD
Sbjct: 533 KGRPGIIRGM--DMGAKVPDEHMIPIENLMNPRA-------LDFHAETGFIYFADTTSYL 583
Query: 2332 IYR----------IRPDGEGAA------PVLVTHNDGLFSMSFDWISKQLYYVDN-IRNS 2460
I R I DG+G P +T + ++ DW+ LY+ D+ + +
Sbjct: 584 IGRQKIDGTERETILKDGKGVRGSPPGIPYTLTGIHNVEGVAVDWMGDNLYWTDDGPKKT 643
Query: 2461 LEVVKIGETGLVHPDELVRRQLIT-ELRDPVSVVVHPWKGLLFYAE------AMRPAAIY 2619
+ V ++ + R+ LI ++ P ++VV P G +++ + R +
Sbjct: 644 ISVARLEKAAQT------RKTLIEGKMTHPRAIVVDPLNGWMYWTDWEEDPKDSRRGRLE 697
Query: 2620 RCHIDGQNCQV-IRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDG--KNVVKLDI 2790
R +DG + + + + T+ P+ +++D RL W D I + +G + +V
Sbjct: 698 RAWMDGSHRDIFVTSKTVLWPNGLSLDIPAGRLYWVDAFYDRIETILLNGTDRKIVYEGP 757
Query: 2791 DNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQ 2970
+ + Y+++ R S+ R+ + G V ++ IF ++ Q Q
Sbjct: 758 ELNHAFGLCHHGNYLFWTEYRSGSVYRLERGVAGAQPTVTLLRSERPPIFEIRMYDAQQQ 817
Query: 2971 PIPDDSREHPCRASQ--CTQLCFATPSESHPNELEAKCACRQGFMINKENNHSCQKDPAE 3144
+ + CR + C+ LC ATP +CAC + +++ + +C +P+
Sbjct: 818 QVGTNK----CRVNNGGCSSLCLATPGSR-------QCACAEDQVLDADGV-TCLANPSY 865
Query: 3145 KIEQLCSSNSTQFQCKNGRCIPKEWKCDGENDCLDESDEIDEKGDKCFHETECAENTIKC 3324
C +F C N RCI + WKCDG+NDCLD SDE C ++T
Sbjct: 866 VPPPQCQPG--EFACANNRCIQERWKCDGDNDCLDNSDEAPAL---------CHQHT--- 911
Query: 3325 RNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNHRCIPEQWKXXXX 3504
C + +F+C+N+RCIP +W
Sbjct: 912 -------------------------------------CPSDRFKCENNRCIPNRWLCDGD 934
Query: 3505 XXXXXXXXEKLEMCGNATCAANQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQC 3684
E C TC NQFSCA+GRCIPI W CD D+DC D +DE P
Sbjct: 935 NDCGNSEDESNATCSARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPTCF 994
Query: 3685 SALQFRCANGRQCVPLR--------------NHXXXXXXXXXXXXXXXXAVTAESCTPDQ 3822
QF C NGR C+ + A + SC+ Q
Sbjct: 995 PLTQFTCNNGR-CININWRCDNEKDCGDGSDEKTCPEPADNDCGDNSDEAGCSHSCSSTQ 1053
Query: 3823 FKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQ-----CSSDQFKCG-NGRCILN 3984
FKC +SG CIP W SDE CT+ C SD+F+C +G CI
Sbjct: 1054 FKC-NSGRCIPEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHSDEFQCRLDGLCIPL 1112
Query: 3985 NWLCDGENDCGDGSDESS------------ERGCKTSMN--------------------- 4065
W CDG+ DC D SDE + GCK S
Sbjct: 1113 RWRCDGDTDCMDSSDEKGCEGVTHVCDPNVKFGCKDSARCISKAWVCDGDSDCEDNSDEE 1172
Query: 4066 ---ARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCSFKC 4236
A C C N+ C+ +LCDGK C G+DEG C D CS + GCS C
Sbjct: 1173 NCEALACRPPSHPCANNTSVCLSPDKLCDGKDDCGDGSDEGELC--DQCSLNNGGCSHNC 1230
Query: 4237 HNSPN-GPICSCPFGEQL-VNKTKCEPENECLDSSSCSQRCKDEKHGFTCSCDEGYELDV 4410
+P G +CSCP G +L + C+ ++ C CSQ+C K CSC EG+ L+
Sbjct: 1231 SVAPGEGIVCSCPLGMELGPDNHTCQIQSYCAKHLKCSQKCDQNKFSVKCSCYEGWVLEP 1290
Query: 4411 DKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGAIVENAIALAWDSLTDRIYWSD 4590
D +C+ D K I+ SNR+ I D ++ + N IAL + +YW+D
Sbjct: 1291 DGESCRSLDPFKPFIIF-SNRHEIRRIDLHKGDYSVLVPGLRNTIALDFHLSQSALYWTD 1349
Query: 4591 IREKKI----LSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVDSSLNTIEVANLED 4758
+ E KI L N T+ V I GL EG+A+DW+ N+YWV+S+L+ IEVA L D
Sbjct: 1350 VVEDKIYRGKLLDNGALTSFEVVIQYGLATPEGLAVDWIAGNIYWVESNLDQIEVAKL-D 1408
Query: 4759 PKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQN-PCIERASMDGTDRQIIVKTKIY-- 4929
RT L+ ++ PR IA+DPR G++FWTDW + P IE ASM G R+ I +
Sbjct: 1409 GTLRTTLLAGDIEHPRAIALDPRDGILFWTDWDASLPRIEAASMSGAGRRTIHRETGSGG 1468
Query: 4930 WPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFEDMMYYS 5109
WPN + +DY R+ + D++ D I YDGSG +VL +F+ HP A+ ++ +Y++
Sbjct: 1469 WPNGLTVDYLEKRILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYGGEVYWT 1528
Query: 5110 DRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTN----PCSHL 5277
D R L K+ G T ++ + HP QP+ N PC N PCSHL
Sbjct: 1529 DWRTNTLAKANKW-TGHNVTVVQRTNTQPFDLQVYHPSRQPMAPN-PCEANGGRGPCSHL 1586
Query: 5278 CLLNNKNTFTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNVFGIEMNSASEKETPVLAG 5457
CL+N T +C CP KL C + K FL+ ++ + G+++++ +++
Sbjct: 1587 CLINYNRTVSCACPHLMKLHNDNTTCYE-FKKFLLYARQMEIRGVDLDAPYYNY--IISF 1643
Query: 5458 MVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNGGNKTKMFSSA 5637
VP + N YDA + ++ + AI R+ +NG + S+
Sbjct: 1644 TVP--DIDNVTVLDYDAREQRVYWSD-----------VRTQAIKRAFINGTGVETVVSAD 1690
Query: 5638 VPDDAYCLGFDWNGRNLVVGNKIT--QTIEIIRTQGKQYRSVILSNDQSXXXXXXXXXXX 5811
+P+ A+ L DW RNL + T + I + R G +V+ +Q
Sbjct: 1691 LPN-AHGLAVDWVSRNLFWTSYDTNKKQINVARLDGSFKNAVVQGLEQPHGLVVHPL--- 1746
Query: 5812 XXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAIDTTNTRVYFSEA 5991
+G ++W D ++ +DGSN ++ S + +AID +++Y+ +
Sbjct: 1747 ----RGKLYWTDGDN------ISMVNMDGSNRTLLFSGQKGPVG-LAIDFPESKLYWISS 1795
Query: 5992 KAGRISSVTYDGQDRHYVLSDGGR--QPNGLAFYGDRLFYADSAFDSIEVATINGDSQPP 6165
I+ DG + + + + + LA GD+L++AD + + S
Sbjct: 1796 GNHTINRCNLDGSELEVIDTMRSQLGKATALAIMGDKLWWADQVSEKMGTCNKADGSGSV 1855
Query: 6166 QWTHFKKDVENLANIKALQPRASSSGHPCHINNGNCDHICIPLMFAQRTCTCANGY-VKD 6342
+ V ++ +PC +NNG+C +C+P R+C C GY ++
Sbjct: 1856 VLRNSTTLVMHMKVYDESIQLEHEGTNPCSVNNGDCSQLCLPTSETTRSCMCTAGYSLRS 1915
Query: 6343 GQTSCKLFDESFVIVATKTKVIGYPIDETQSKGVAMEPIGGLSIT-GVDYDYESKTIYVA 6519
GQ +C+ SF++ + + G P+D K A+ P+ G S+ G+D+ E+ TIY
Sbjct: 1916 GQQACEGVG-SFLLYSVHEGIRGIPLDPND-KSDALVPVSGTSLAVGIDFHAENDTIYWV 1973
Query: 6520 EA--SGINKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINYNMYFINHDAERTNIEV 6693
+ S I++ T E V+ + IG ++ +A+DWI N+Y+ + + IEV
Sbjct: 1974 DMGLSTISRAKRDQTWRED----VVTNGIGR--VEGIAVDWIAGNIYWTDQGFDV--IEV 2025
Query: 6694 SKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQRSFLDGSRREVIVSSGI 6873
++L+G++R ++++ + P +I V P YL+W + G P I+RS LDG+ R V+V+ I
Sbjct: 2026 ARLNGSFRYVVISQGLDKPRAITVHPEKGYLFWTEWGHYPRIERSRLDGTERVVLVNVSI 2085
Query: 6874 AEPTDLVVDVASKMIYWSDAKMDGIYRVR-STGGTPELV-RSDIASAAGVALHGQNMYWT 7047
+ P + VD +YW DA+MD I R+ TG E+V S+ V++ +YW+
Sbjct: 2086 SWPNGISVDYQGGKLYWCDARMDKIERIDLETGENREVVLSSNNMDMFSVSVFEDFIYWS 2145
Query: 7048 DN-RLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRASSPCQITDNLRK 7224
D + K N T + T + LKDI VF+ + Q + ++ C + +
Sbjct: 2146 DRTHANGSIKRGCKDNATDSVPLRTGIGVQLKDI---KVFNRDRQ-KGTNVCAVANG--- 2198
Query: 7225 SPCTQLCFATPGTQTPTCSCARGVLK--GRTCEEPDTYIMFSDGDKIIDVAIEPDVKASR 7398
C QLC G Q C+CA G+L G +C E Y+++S+ + + + + +
Sbjct: 2199 -GCQQLCLYRGGGQR-ACACAHGMLAEDGASCREYAGYLLYSERTILKSIHLSDERNLNA 2256
Query: 7399 PLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAENPRLVF--GASKQPH 7572
P++ PF + +++ + L Y SP N +FS + N + + G+ +
Sbjct: 2257 PVQ-PFEDPEHMKNV---IALAFDYRAGTSPGTPNRIFFSDIHFGNIQQINDDGSGRTTI 2312
Query: 7573 AKEIRHISDMKLDWLTQKIYFTTGRGGKVM--AIDTAG------EHLSTIASGDWTYALA 7728
+ + + + +Y+T+ + +D E + T++ D A
Sbjct: 2313 VENVGSVEGLAYHRGWDTLYWTSYTTSTITRHTVDQTRPGAFERETVITMSGDDHPRAFV 2372
Query: 7729 IDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVDFRNQKIY 7908
+D C L+FW T+ P I R+ L+G + ++ + I P +A+D R +K+Y
Sbjct: 2373 LDECQNLMFW------TNWNELHPSIMRAALSGANVLTLIEKDIRTPNGLAIDHRAEKLY 2426
Query: 7909 WADVNRLNIEVADYDGQNRKVIASGYRAK--SLDIWDRWLYMSDPLSNGVFRIDKESGSG 8082
++D IE +YDG +R VI L ++ ++ +D + V R +K GS
Sbjct: 2427 FSDATLDKIERCEYDGSHRYVILKSEPVHPFGLAVYGEHIFWTDWVRRAVQRANKYVGSD 2486
Query: 8083 LENVVSDRRIPGA-LRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLCTVVADDIGLA 8259
++ + D IP + + A +D N+ C+ +NGGC LC +
Sbjct: 2487 MKLLRVD--IPQQPMGIIAVANDT-------NSCELSPCRINNGGCQDLCLLTHQ----- 2532
Query: 8260 ASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSEPAKECLPPYNFQCGDGSCILLGATCD 8439
V CSC G+ R NS C F+C +G CI TCD
Sbjct: 2533 -GHVNCSCRG--------GRILQEDFTCRAMNSS----CRAQDEFECANGECISFSLTCD 2579
Query: 8440 SKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHIDDCGDGSDELDCPSAVA 8619
C D SDE P+YCN+R C + + C N RC+ + CN +DDCGDGSDE+ C + A
Sbjct: 2580 GVSHCKDKSDEKPSYCNSRRCKKTFRQCNNGRCVSNMLWCNGVDDCGDGSDEIPC-NKTA 2638
Query: 8620 CAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDE---SLATCPG-LPIDCRGVKVR-CPN 8784
C G F C +G CI + C+ DC D SDE S C + +GV + C
Sbjct: 2639 CGVGEFRCRDGSCIGNSSRCNQFVDCED--ASDEMNCSATDCSSYFRLGVKGVLFQPCER 2696
Query: 8785 TNICIQPADLCDGYDDCGDKADENQLFCMNQ-QCAQHYVRCPSGRCIPETWQCDGDNDCS 8961
T++C P+ +CDG +DCGD +DE + + +C +Y CPSGRCIP +W CD ++DC
Sbjct: 2697 TSLCYAPSWVCDGANDCGDYSDERDSPGVKRPRCPLNYFACPSGRCIPMSWTCDKEDDCE 2756
Query: 8962 DGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXXXXXXHSRHGCGNR 9141
+G DETH N K C + F+C N +CIS+ ++ + C +
Sbjct: 2757 NGEDETHCN-------KFC-SEAQFECQNHRCISKQWLCDGSDDCGDGSDEAAH--CEGK 2806
Query: 9142 TCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECNKGEFRC 9321
TC F C + C+P WLCDGD CA G DES C+ EF C
Sbjct: 2807 TCGPSSFSCPGT-------HVCVPERWLCDGDKDCADGADESISAGCLYNSTCDDREFMC 2859
Query: 9322 SNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCANHKCVPN-SWKCDGNDDCE 9498
N+ CI + CD D DC DGSDE C Y +C P+ F+CAN +C+ + W+CDG +DC
Sbjct: 2860 QNRLCIPKHFVCDHDRDCADGSDESPECEYPTCGPNEFRCANGRCLSSRQWECDGENDCH 2919
Query: 9499 DGSDEKDCPKNSASAQKASKC-SNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLCFID 9675
D SDE PKN KC ++ QF C+SG C+ +A +C+ DC D SDE C ++
Sbjct: 2920 DHSDE--APKNPHCTSPEHKCNASSQFLCSSGRCVAEALLCNGQDDCGDGSDERG-CHVN 2976
Query: 9676 ECSLAEKPLCEQKCMDMKIGYK--CDCFEGFAIDISDQKSCHNVNECYEGISGCSQKCDD 9849
EC + C Q C D+KIG+K C C GF + D ++C +V+EC CSQ C +
Sbjct: 2977 ECLSRKLSGCSQDCEDLKIGFKVHCRCRPGFRLK-DDGRTCADVDECSTTFP-CSQLCIN 3034
Query: 9850 KIGSYKCGCVDGY-QLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYELAAQGFD 10026
GSYKC CV+GY D HSCK E EPF + AN++Y+RK+++DG+ Y L QG +
Sbjct: 3035 THGSYKCLCVEGYAPRGGDPHSCKAVTDE-EPFLIFANRYYLRKLNLDGSNYTLLKQGLN 3093
Query: 10027 NVVSLDIDLTEKKAYLID---QGKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDW 10197
N V+LD D + Y D QG + + R+ L+ S+ + + R + +G+AVDW
Sbjct: 3094 NAVALDFDYRGQMIYWTDVTTQGSM-IRRMHLNG-----SNVQVLHRTGLSNPDGLAVDW 3147
Query: 10198 VGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFFTEWSLQPYIG 10377
VG LY ++ +I V +L+G + L+ +++P+A+VV GYL++T+W IG
Sbjct: 3148 VGGNLYWCDKGRDTIEVSKLNGAYRTVLVSSGLREPRALVVDVQNGYLYWTDWGDHSLIG 3207
Query: 10378 RIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGR--- 10548
RI +DGS + + + WPN + +DY ++R++W DA + I F DG+ R
Sbjct: 3208 RIGMDGSGR-----SIIVDTKITWPNGLTVDYVTERIYWADAREDYIEFASLDGSNRHVG 3262
Query: 10549 -------------RH--------------------IPAQRTSHVSSMVVFDDYLYWADWN 10629
RH + +Q H+ ++ +F+DY+YW DW
Sbjct: 3263 PYARLRWDSRRSGRHGTQSVLGANFCSVSPASPPTVLSQDIPHIFALTLFEDYVYWTDWE 3322
Query: 10630 LREVLRCDKWTGKNETILKKTVQLPNDLRIVHPMRQPAYPN-PCGDNNGGCSHLCLIGAG 10806
+ + R K TG N+T+L T+ P DL + H +RQP PN PC NNGGCS+LCL+ G
Sbjct: 3323 TKSINRAHKTTGANKTLLISTLHRPMDLHVFHALRQPDVPNHPCKVNNGGCSNLCLLSPG 3382
Query: 10807 GNGYTCSCPDQFVLLSDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPG 10986
G G+ C+CP F L D +TC NCT QF C D KCIP W CD E DC D SDEP
Sbjct: 3383 G-GHKCACPTNFYLGGDGRTCVSNCTASQFVCKND--KCIPFWWKCDTEDDCGDHSDEPP 3439
Query: 10987 ESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXXEQNCD-KACDPWMFKCAATGR 11163
+ C + C G+FQC+ CT P I E NCD C P FKC T R
Sbjct: 3440 D--CPEFKCRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCTNTNR 3497
Query: 11164 CIPRRFTXXXXXXXXXRSDEADTLCMSAERNCTAEEFRCN-NNKCIAKAWRXXXXXXXXX 11340
CIP F DE D E C +F+C+ +CI + W
Sbjct: 3498 CIPGIFRCNGQDNCGDGEDERD----CPEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVD 3553
Query: 11341 XXXETPECAQIECKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCP--TCDDVGE 11514
E C Q+ C RC S RCIP C+G+DDC D SDE K+ C TC+ +
Sbjct: 3554 GSDEPANCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPY-Q 3612
Query: 11515 FRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCD 11694
FRC + +C+P RW CD +NDCGDNSDE SC T RPCSESEF C +G+CI G CD
Sbjct: 3613 FRC-KNNRCVPGRWQCDYDNDCGDNSDE--ESC--TPRPCSESEFSCANGRCIAGRWKCD 3667
Query: 11695 GTIQCSDGLDESQCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRT 11874
G C+DG DE CT RC QC G CI CD DC + +DE C T
Sbjct: 3668 GDHDCADGSDEKDCT-PRCDMDQFQCKSGHCIPLRWRCDADADCMDGSDEEAC-GTGGET 3725
Query: 11875 CSPFEFECANSVCIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNIL 12054
C EF+C N++C P + SDE EC QC P FRC + R+CL I
Sbjct: 3726 CPLDEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEECTRFQCPPNRPFRCKNDRVCLWIG 3785
Query: 12055 QLCNGFNDCGPNDFSDEHLSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDAS 12234
+ C+G ++CG D +DE + +F C N +C++ ++ C+ DDCGD S
Sbjct: 3786 RQCDGTDNCG--DGTDEEDCEPPTAQNPHCKDKKEFLCRNQRCLSSSLRCNMFDDCGDGS 3843
Query: 12235 DEIGCSKHGGKTSCEAFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAG 12414
DE CS TSC + G + C YC CR GF P P C DI+EC
Sbjct: 3844 DEEDCSIDPKLTSCATNASMCGDEARCVRTEKAAYCACRPGFHTVPGQP-GCQDINECLR 3902
Query: 12415 NNTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLH 12594
TC+QLC NTKG +LC C ++ T C+A+G V+ ADD+ ++
Sbjct: 3903 FGTCSQLCNNTKGGHLCSCARNF-------MKTHNTCKAEGSEYQVLYIADDNEIRSLFP 3955
Query: 12595 GSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERTI-YRS---AIANGNQSHEGQ 12762
G + + + +YW + TI YRS A + +
Sbjct: 3956 GHPHSAYEQAFQGDESVRIDAMDVHVKAGRVYWTNWHTGTISYRSLPPAAPPTTSNRHRR 4015
Query: 12763 KLDVDFAAMGV----VPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTG 12930
++D + + +P IA+D+ GN++ ++
Sbjct: 4016 QIDRGVTHLNISGLKMPRGIAIDWVAGNVYWTDSGRDV---------------------- 4053
Query: 12931 FIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIV 13110
I V G K +++G + +P A++ P G + +SD G H KIE A MDGT R+ +V
Sbjct: 4054 -IEVAQMKGENRKTLISGMIDEPHAIVVDPLRGTMYWSDWGNHPKIETAAMDGTLRETLV 4112
Query: 13111 KDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRH---IPYAVDVFE 13281
+D + PT +A+D R+YW D K + ++ ++G++ V + P+++DVFE
Sbjct: 4113 QDNIQWPTGLAVDY-HNERLYWADAKLSVIGSIRLNGTDPIVAVDSKRGLSHPFSIDVFE 4171
Query: 13282 NHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCS 13461
++IY ++ + ++ KFG + L L H V + + C+R +C
Sbjct: 4172 DYIYGVTYINNRVFKIHKFGHSPLINLTGGL--SHASDVVLYHQHKQPEVTNPCDRKKCE 4229
Query: 13462 HLCVSLPSTGFACLCPDGIVPQLD-GSCATQHVEALTMPKQC--------KCTNGGKCRL 13614
LC+ PS G C CP+G +LD G+C V + T P +C NGG C L
Sbjct: 4230 WLCLLSPS-GPVCTCPNG--KRLDNGTCVP--VPSPTPPPDAPRPGTCTLQCFNGGSCFL 4284
Query: 13615 DG----SCECTSDFEGDQCE 13662
+ C C + GD+CE
Sbjct: 4285 NARRQPKCRCQPRYTGDKCE 4304
Score = 363 bits (932), Expect = 7e-98
Identities = 286/1038 (27%), Positives = 444/1038 (42%), Gaps = 38/1038 (3%)
Frame = +1
Query: 130 ASVNTASSVCNENDFRCNDGKCIRTEWX-XXXXXXXXXXXXXXXXPHPGCKSDQWQCDTY 306
++ ++ C N F C G+CI W +P C + +
Sbjct: 944 SNATCSARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPTC----FPLTQF 999
Query: 307 TWHSVSCIAEYQRCDNITDCADGSDEKDCP----------ASTVDCS---SQNVFMCADG 447
T ++ CI RCDN DC DGSDEK CP + CS S F C G
Sbjct: 1000 TCNNGRCININWRCDNEKDCGDGSDEKTCPEPADNDCGDNSDEAGCSHSCSSTQFKCNSG 1059
Query: 448 RQCFDVSKKCDGKYDCRDLSDEKD-SCSRNHT----ACFQYQFRCADKTQCIQKSWVCDG 612
R C CDG DC D SDE +C+ T C +F+C CI W CDG
Sbjct: 1060 R-CIPEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHSDEFQCRLDGLCIPLRWRCDG 1118
Query: 613 SKDCADGSDEPDTCE--FKKCTAN-EFQCKNK-RCQPRKFRCDYYDDCGDNSDEDECGEY 780
DC D SDE CE C N +F CK+ RC + + CD DC DNSDE+ C
Sbjct: 1119 DTDCMDSSDEKG-CEGVTHVCDPNVKFGCKDSARCISKAWVCDGDSDCEDNSDEENCEAL 1177
Query: 781 RCPPGKWNCP-GTGHCIDQLKLCDGSKDCADGADE-QQCSQNLCPSLGCQAGCHPSP-HG 951
C P C T C+ KLCDG DC DG+DE + C Q + GC C +P G
Sbjct: 1178 ACRPPSHPCANNTSVCLSPDKLCDGKDDCGDGSDEGELCDQCSLNNGGCSHNCSVAPGEG 1237
Query: 952 GECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPG 1131
C+CP G +L H TC + CA+ C Q C ++ CSC + + L+ + G
Sbjct: 1238 IVCSCPLGMELGPDNH-TCQIQSYCAKHLKCSQKCDQNKFSVKCSCY-EGWVLEPD---G 1292
Query: 1132 KDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKLASG-EFIYGIDFDYGDR 1308
+ C S + K + + R + R++ D V L G +DF
Sbjct: 1293 ES-------CRSLDPFKPFIIFSNRHEIRRIDLHKGDYSV--LVPGLRNTIALDFHLSQS 1343
Query: 1309 KIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRID 1488
++WTD + + + D G ++ + + L P LAVDWI +Y +ES +I+
Sbjct: 1344 ALYWTDVVEDKIYRGKLLDNGALTSFEVVIQYGLATPEGLAVDWIAGNIYWVESNLDQIE 1403
Query: 1489 VSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFT----NQLKLEAAAMDGTNRRTLVNT 1656
V+ DG RT LLA + P IALDP G +F+T + ++EAA+M G RRT ++
Sbjct: 1404 VAKLDGTLRTTLLAGDIEHPRAIALDPRDGILFWTDWDASLPRIEAASMSGAGRRT-IHR 1462
Query: 1657 HTHQ---VSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFD 1827
T +G+ VD KR+ W+D + D + S Y G+ V +G + HPF + L+
Sbjct: 1463 ETGSGGWPNGLTVDYLEKRILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYG 1522
Query: 1828 QYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKI 2007
+YWTDW + + K+ + T N P + YHP QP + C A
Sbjct: 1523 GEVYWTDWRTNTLAKANKWTGHNVTVVQRT--NTQPFDLQVYHPSRQP-MAPNPCEANGG 1579
Query: 2008 ENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVN-GKRCIDSIDYLLFSSNKIVRG 2184
PC++ +C+++ + CACP KL N C + +LL++ +RG
Sbjct: 1580 RGPCSH-----LCLIN-----YNRTVSCACPHLMKLHNDNTTCYEFKKFLLYARQMEIRG 1629
Query: 2185 IFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGA 2364
+ + A I + I ++ D +++D+ I R +G G
Sbjct: 1630 VDLD------APYYNYIISFTVPDIDNVTVLDYDAREQRVYWSDVRTQAIKRAFINGTGV 1683
Query: 2365 APVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRD 2544
V+ ++ DW+S+ L++ N ++ + D + ++ L
Sbjct: 1684 ETVVSADLPNAHGLAVDWVSRNLFWTSYDTNKKQI------NVARLDGSFKNAVVQGLEQ 1737
Query: 2545 PVSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWG 2724
P +VVHP +G L++ + I ++DG N ++ + G P +AIDF E++L W
Sbjct: 1738 PHGLVVHPLRGKLYWTDGDN---ISMVNMDGSNRTLLFSGQKG-PVGLAIDFPESKLYWI 1793
Query: 2725 DTLLKTISCMDFDGKNVVKLDIDNP---IPVAITIMNEYIYYVHQRPYSIRRVHKKNGGG 2895
+ TI+ + DG + +D A+ IM + +++ Q + +K +G G
Sbjct: 1794 SSGNHTINRCNLDGSELEVIDTMRSQLGKATALAIMGDKLWWADQVSEKMGTCNKADGSG 1853
Query: 2896 SKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAK 3075
S ++R + +K Q + + C+QLC T +E
Sbjct: 1854 SVVLRN---STTLVMHMKVYDESIQLEHEGTNPCSVNNGDCSQLCLPT------SETTRS 1904
Query: 3076 CACRQGFMINKENNHSCQ 3129
C C G+ + + +C+
Sbjct: 1905 CMCTAGYSL-RSGQQACE 1921
Score = 313 bits (802), Expect = 8e-83
Identities = 221/745 (29%), Positives = 322/745 (42%), Gaps = 83/745 (11%)
Frame = +1
Query: 139 NTASSVCNENDFRCND-GKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWH 315
N C ++FRC D G+CI W P + D+ C+ Y +
Sbjct: 3560 NCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDGSD-----EPKEECDERTCEPYQFR 3614
Query: 316 SVS--CIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKY 489
+ C+ +CD DC D SDE+ C T S++ F CA+GR C KCDG +
Sbjct: 3615 CKNNRCVPGRWQCDYDNDCGDNSDEESC---TPRPCSESEFSCANGR-CIAGRWKCDGDH 3670
Query: 490 DCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEF--K 663
DC D SDEKD R C QF+C CI W CD DC DGSDE + C +
Sbjct: 3671 DCADGSDEKDCTPR----CDMDQFQCKSG-HCIPLRWRCDADADCMDGSDE-EACGTGGE 3724
Query: 664 KCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDE--DECGEYRCPPGK-WNCPGTGHCIDQ 834
C +EFQC N C+P ++CD DDCGDNSDE +EC ++CPP + + C C+
Sbjct: 3725 TCPLDEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEECTRFQCPPNRPFRCKNDRVCLWI 3784
Query: 835 LKLCDGSKDCADGADEQQC----SQN----------------LCPSLGC----------- 921
+ CDG+ +C DG DE+ C +QN L SL C
Sbjct: 3785 GRQCDGTDNCGDGTDEEDCEPPTAQNPHCKDKKEFLCRNQRCLSSSLRCNMFDDCGDGSD 3844
Query: 922 ----------------------QAGCHPSPHGGECTCPSGYKLDDRFHRT-----CSDIN 1020
+A C + C C G FH C DIN
Sbjct: 3845 EEDCSIDPKLTSCATNASMCGDEARCVRTEKAAYCACRPG------FHTVPGQPGCQDIN 3898
Query: 1021 ECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVA 1200
EC FG C QLC N + G CSC ++ + C + ++ L++A
Sbjct: 3899 ECLRFGTCSQLCNNTKGGHLCSC-------------ARNFMKTHNTCKAEGSEYQVLYIA 3945
Query: 1201 RREGLYRLNPKNPDEEVKKLASGEF---IYGIDFDYGDRKIFWTD----RLAHSAF---S 1350
+ L P +P ++ G+ I +D +++WT+ +++ + +
Sbjct: 3946 DDNEIRSLFPGHPHSAYEQAFQGDESVRIDAMDVHVKAGRVYWTNWHTGTISYRSLPPAA 4005
Query: 1351 ADVDDEGEISQIKK----LSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRT 1518
QI + L++ L PR +A+DW+ +Y +SG I+V+ GE R
Sbjct: 4006 PPTTSNRHRRQIDRGVTHLNISGLKMPRGIAIDWVAGNVYWTDSGRDVIEVAQMKGENRK 4065
Query: 1519 VLLADGLTLPLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVD 1689
L++ + P I +DPLRG M+++ N K+E AAMDGT R TLV + +G+ VD
Sbjct: 4066 TLISGMIDEPHAIVVDPLRGTMYWSDWGNHPKIETAAMDGTLRETLVQDNIQWPTGLAVD 4125
Query: 1690 ITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVI 1869
+R+YW D K+ + SI G D + + HPF + +F+ Y+Y + V
Sbjct: 4126 YHNERLYWADAKLSVIGSIRLNGTDPIVAVDSKRGLSHPFSIDVFEDYIYGVTYINNRVF 4185
Query: 1870 QVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCI 2049
++ KFG L + T + YH QP ++ NPC CE +C+
Sbjct: 4186 KIHKFGHSP--LINLTGGLSHASDVVLYHQHKQP----------EVTNPCDRKKCEWLCL 4233
Query: 2050 LSKDNGGFGVGYKCACPIGQKLVNG 2124
LS G C CP G++L NG
Sbjct: 4234 LSPS------GPVCTCPNGKRLDNG 4252
Score = 308 bits (790), Expect = 2e-81
Identities = 218/719 (30%), Positives = 311/719 (42%), Gaps = 57/719 (7%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAE 336
C N F C G+CI W + C Q++C + CI++
Sbjct: 2730 CPLNYFACPSGRCIPMSWTCDKEDDCENGEDETHC-NKFCSEAQFECQNHR-----CISK 2783
Query: 337 YQRCDNITDCADGSDEK-DCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDE 513
CD DC DGSDE C T SS F C C CDG DC D +DE
Sbjct: 2784 QWLCDGSDDCGDGSDEAAHCEGKTCGPSS---FSCPGTHVCVPERWLCDGDKDCADGADE 2840
Query: 514 KDS--CSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQ 687
S C N T C +F C ++ CI K +VCD +DCADGSDE CE+ C NEF+
Sbjct: 2841 SISAGCLYNST-CDDREFMCQNRL-CIPKHFVCDHDRDCADGSDESPECEYPTCGPNEFR 2898
Query: 688 CKNKRC-QPRKFRCDYYDDCGDNSDE----DEC--GEYRCPPGKWNCPGTGHCIDQLKLC 846
C N RC R++ CD +DC D+SDE C E++C +G C+ + LC
Sbjct: 2899 CANGRCLSSRQWECDGENDCHDHSDEAPKNPHCTSPEHKCNASSQFLCSSGRCVAEALLC 2958
Query: 847 DGSKDCADGADEQQCSQNLCPS---LGCQAGCHPSPHGGE--CTCPSGYKLDDRFHRTCS 1011
+G DC DG+DE+ C N C S GC C G + C C G++L D RTC+
Sbjct: 2959 NGQDDCGDGSDERGCHVNECLSRKLSGCSQDCEDLKIGFKVHCRCRPGFRLKDD-GRTCA 3017
Query: 1012 DINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRG----YCVSNNAD 1179
D++EC+ C QLC N + C C+ + RG C + +
Sbjct: 3018 DVDECSTTFPCSQLCINTHGSYKCLCV--------------EGYAPRGGDPHSCKAVTDE 3063
Query: 1180 KMKLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADV 1359
+ L A R L +LN + + K + +DFDY + I+WTD + +
Sbjct: 3064 EPFLIFANRYYLRKLNLDGSNYTLLKQGLNNAV-ALDFDYRGQMIYWTDVTTQGSMIRRM 3122
Query: 1360 DDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGL 1539
G S ++ L L P LAVDW+ LY + G I+VS +G RTVL++ GL
Sbjct: 3123 HLNG--SNVQVLHRTGLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVSSGL 3180
Query: 1540 TLPLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVY 1710
P + +D G +++T + + MDG+ R +V+T +G+ VD +R+Y
Sbjct: 3181 REPRALVVDVQNGYLYWTDWGDHSLIGRIGMDGSGRSIIVDTKITWPNGLTVDYVTERIY 3240
Query: 1711 WVDPKVDRLESIDYQGNDRRI-------------------VAQGMNV------------- 1794
W D + D +E G++R + G N
Sbjct: 3241 WADAREDYIEFASLDGSNRHVGPYARLRWDSRRSGRHGTQSVLGANFCSVSPASPPTVLS 3300
Query: 1795 --VPHPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQ 1968
+PH F L LF+ Y+YWTDW + + K K L +T + PM + +H + Q
Sbjct: 3301 QDIPHIFALTLFEDYVYWTDWETKSINRAHKTTGANKTLLISTLHR--PMDLHVFHALRQ 3358
Query: 1969 PGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKL-VNGKRCIDS 2142
P C N C +C+LS G G+KCACP L +G+ C+ +
Sbjct: 3359 PDVPNHPC-------KVNNGGCSNLCLLSP-----GGGHKCACPTNFYLGGDGRTCVSN 3405
Score = 178 bits (451), Expect = 4e-42
Identities = 90/247 (36%), Positives = 125/247 (50%), Gaps = 1/247 (0%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAE 336
C F+C+ G C + C Q++C ++ CI
Sbjct: 3446 CRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCT----NTNRCIPG 3501
Query: 337 YQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEK 516
RC+ +C DG DE+DCP T + N F C+ ++C CD DC D SDE
Sbjct: 3502 IFRCNGQDNCGDGEDERDCPEVTC---APNQFQCSITKRCIPRVWVCDRDNDCVDGSDEP 3558
Query: 517 DSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEP-DTCEFKKCTANEFQCK 693
+C++ C +FRC D +CI W CDG DC DGSDEP + C+ + C +F+CK
Sbjct: 3559 ANCTQ--MTCGVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCK 3616
Query: 694 NKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADG 873
N RC P +++CDY +DCGDNSDE+ C C +++C G CI CDG DCADG
Sbjct: 3617 NNRCVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFSC-ANGRCIAGRWKCDGDHDCADG 3675
Query: 874 ADEQQCS 894
+DE+ C+
Sbjct: 3676 SDEKDCT 3682
Score = 161 bits (407), Expect = 5e-37
Identities = 100/296 (33%), Positives = 130/296 (43%), Gaps = 18/296 (6%)
Frame = +1
Query: 49 NSSTRQQSTFH---------SIQVDSPPSVRSRIISASVNTASSVCNENDFRCNDGKCIR 201
NSS R Q F S+ D + + S C + +CN+G+C+
Sbjct: 2555 NSSCRAQDEFECANGECISFSLTCDGVSHCKDKSDEKPSYCNSRRCKKTFRQCNNGRCVS 2614
Query: 202 TEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSD 381
C +++C SCI RC+ DC D SD
Sbjct: 2615 NMLWCNGVDDCGDGSDEIPCNKTACGVGEFRC-----RDGSCIGNSSRCNQFVDCEDASD 2669
Query: 382 EKDCPASTVDCSS------QNVFM--CADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNH 537
E +C S DCSS + V C C+ S CDG DC D SDE+DS
Sbjct: 2670 EMNC--SATDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDERDSPGVKR 2727
Query: 538 TACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRK 717
C F C +CI SW CD DC +G DE +F C+ +F+C+N RC ++
Sbjct: 2728 PRCPLNYFAC-PSGRCIPMSWTCDKEDDCENGEDETHCNKF--CSEAQFECQNHRCISKQ 2784
Query: 718 FRCDYYDDCGDNSDE-DECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADE 882
+ CD DDCGD SDE C C P ++CPGT C+ + LCDG KDCADGADE
Sbjct: 2785 WLCDGSDDCGDGSDEAAHCEGKTCGPSSFSCPGTHVCVPERWLCDGDKDCADGADE 2840
Score = 147 bits (370), Expect = 1e-32
Identities = 89/245 (36%), Positives = 114/245 (46%), Gaps = 17/245 (6%)
Frame = +1
Query: 430 FMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCD 609
F CA+ R C KCDG DC D SDE + HT C +F+C + +CI W+CD
Sbjct: 876 FACANNR-CIQERWKCDGDNDCLDNSDEAPALCHQHT-CPSDRFKC-ENNRCIPNRWLCD 932
Query: 610 GSKDCADGSDEPD-TCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDED-ECGEYR 783
G DC + DE + TC + C N+F C + RC P + CD DDCGD SDE C
Sbjct: 933 GDNDCGNSEDESNATCSARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPT 992
Query: 784 CPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQC---SQNLCPSLGCQAGCHPSPHGG 954
C P G CI+ CD KDC DG+DE+ C + N C +AGC S
Sbjct: 993 CFPLTQFTCNNGRCININWRCDNEKDCGDGSDEKTCPEPADNDCGDNSDEAGCSHSCSST 1052
Query: 955 ECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCAN------------HRPGFTCSCLGD 1098
+ C SG + + H TC N+C + Y D+ AN H F C G
Sbjct: 1053 QFKCNSGRCIPE--HWTCDGDNDCGD--YSDETHANCTNQATRPPGGCHSDEFQCRLDGL 1108
Query: 1099 CFTLQ 1113
C L+
Sbjct: 1109 CIPLR 1113
Score = 143 bits (360), Expect = 1e-31
Identities = 89/293 (30%), Positives = 128/293 (43%), Gaps = 40/293 (13%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDE-KDCP----------ASTVDCSS 420
C + Q+ C + CI + +CD DC D SDE DCP ST C++
Sbjct: 3406 CTASQFVCK-----NDKCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQFQCSTGICTN 3460
Query: 421 --------------------------QNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDS 522
+ F C + +C +C+G+ +C D DE+D
Sbjct: 3461 PAFICDGDNDCQDNSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDC 3520
Query: 523 CSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNK- 699
C QF+C+ +CI + WVCD DC DGSDEP C C +EF+CK+
Sbjct: 3521 ---PEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDEFRCKDSG 3577
Query: 700 RCQPRKFRCDYYDDCGDNSDE--DECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADG 873
RC P +++CD DDCGD SDE +EC E C P ++ C C+ CD DC D
Sbjct: 3578 RCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCK-NNRCVPGRWQCDYDNDCGDN 3636
Query: 874 ADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAE 1032
+DE+ C+ C E +C +G + R+ C ++CA+
Sbjct: 3637 SDEESCTPRPCSE-------------SEFSCANGRCIAGRW--KCDGDHDCAD 3674
Score = 126 bits (316), Expect = 2e-26
Identities = 88/264 (33%), Positives = 125/264 (47%), Gaps = 11/264 (4%)
Frame = +1
Query: 343 RCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDS 522
+C T+ G D + C ++ C++ F+C + + C KCD + DC D SDE
Sbjct: 3386 KCACPTNFYLGGDGRTCVSN---CTASQ-FVCKNDK-CIPFWWKCDTEDDCGDHSDEPPD 3440
Query: 523 CSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKN-K 699
C C QF+C+ C +++CDG DC D SDE + C+ C ++F+C N
Sbjct: 3441 CPE--FKCRPGQFQCSTGI-CTNPAFICDGDNDCQDNSDEAN-CDIHVCLPSQFKCTNTN 3496
Query: 700 RCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGAD 879
RC P FRC+ D+CGD DE +C E C P ++ C T CI ++ +CD DC DG+D
Sbjct: 3497 RCIPGIFRCNGQDNCGDGEDERDCPEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSD 3556
Query: 880 E-QQCSQNLC--PSLGCQ--AGCHPS--PHGGECTCPSGYKLDDRFHRTCSDINECAEFG 1038
E C+Q C C+ C P+ GE C G D C D C +
Sbjct: 3557 EPANCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDG---SDEPKEEC-DERTCEPYQ 3612
Query: 1039 YCDQLCANHR--PG-FTCSCLGDC 1101
+ C N+R PG + C DC
Sbjct: 3613 F---RCKNNRCVPGRWQCDYDNDC 3633
Score = 106 bits (264), Expect = 2e-20
Identities = 59/172 (34%), Positives = 78/172 (45%)
Frame = +1
Query: 391 CPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCA 570
C + CS+ + G +C C + L + +C N TA QF C
Sbjct: 3366 CKVNNGGCSNLCLLSPGGGHKC-----ACPTNFY---LGGDGRTCVSNCTAS---QFVCK 3414
Query: 571 DKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGD 750
+ +CI W CD DC D SDEP C KC +FQC C F CD +DC D
Sbjct: 3415 ND-KCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQFQCSTGICTNPAFICDGDNDCQD 3473
Query: 751 NSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLC 906
NSDE C + C P ++ C T CI + C+G +C DG DE+ C + C
Sbjct: 3474 NSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTC 3525
Score = 105 bits (261), Expect = 4e-20
Identities = 87/282 (30%), Positives = 118/282 (40%), Gaps = 23/282 (8%)
Frame = +1
Query: 325 CIAEYQRCDNITDCADG---SDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDC 495
C+ +Q N + C G ++ C A C +Q+ F CA+G +C S CDG C
Sbjct: 2527 CLLTHQGHVNCS-CRGGRILQEDFTCRAMNSSCRAQDEFECANG-ECISFSLTCDGVSHC 2584
Query: 496 RDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTA 675
+D SDEK S N C + FR + +C+ C+G DC DGSDE C C
Sbjct: 2585 KDKSDEKPSYC-NSRRC-KKTFRQCNNGRCVSNMLWCNGVDDCGDGSDE-IPCNKTACGV 2641
Query: 676 NEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPG---------KWNCPGTGHCI 828
EF+C++ C RC+ + DC D SDE C C C T C
Sbjct: 2642 GEFRCRDGSCIGNSSRCNQFVDCEDASDEMNCSATDCSSYFRLGVKGVLFQPCERTSLCY 2701
Query: 829 DQLKLCDGSKDCADGADEQQ---CSQNLCP--SLGCQAG-CHPSPH--GGECTCPSGYKL 984
+CDG+ DC D +DE+ + CP C +G C P E C +G
Sbjct: 2702 APSWVCDGANDCGDYSDERDSPGVKRPRCPLNYFACPSGRCIPMSWTCDKEDDCENG--- 2758
Query: 985 DDRFHRTCSDINECAEFGYCDQLCANHR---PGFTCSCLGDC 1101
+D H C+ A+F C NHR + C DC
Sbjct: 2759 EDETH--CNKFCSEAQFE-----CQNHRCISKQWLCDGSDDC 2793
Score = 102 bits (253), Expect = 4e-19
Identities = 124/492 (25%), Positives = 193/492 (39%), Gaps = 45/492 (9%)
Frame = +1
Query: 7198 CQ-ITDNLRKSPCTQLCFATPGTQTPTCSCARGVLKGR-TC--EEPDTYIMFSDGDKIID 7365
CQ I + LR C+QLC T G CSCAR +K TC E + +++ D I
Sbjct: 3894 CQDINECLRFGTCSQLCNNTKGGHL--CSCARNFMKTHNTCKAEGSEYQVLYIADDNEIR 3951
Query: 7366 VAIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAENPRL 7545
++ E + DV V RVY+ G IS+ S+ A P
Sbjct: 3952 SLFPGHPHSAYEQAFQGDESVRIDAMDVHVKAGRVYWT-NWHTGT-ISYRSLPPAAPP-- 4007
Query: 7546 VFGASKQPHAKEIR------HISDMKL------DWLTQKIYFTTGRGGKVMAIDTAGEHL 7689
+ H ++I +IS +K+ DW+ +Y+T + GE+
Sbjct: 4008 ---TTSNRHRRQIDRGVTHLNISGLKMPRGIAIDWVAGNVYWTDSGRDVIEVAQMKGENR 4064
Query: 7690 STIASG--DWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESIS 7863
T+ SG D +A+ +DP G ++WSD G P+IE + + G R+ +V ++I
Sbjct: 4065 KTLISGMIDEPHAIVVDPLRGTMYWSDWGN-------HPKIETAAMDGTLRETLVQDNIQ 4117
Query: 7864 LPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGYRAK----SLDIWDRWLYMS 8031
P +AVD+ N+++YWAD I +G + V R S+D+++ ++Y
Sbjct: 4118 WPTGLAVDYHNERLYWADAKLSVIGSIRLNGTDPIVAVDSKRGLSHPFSIDVFEDYIYGV 4177
Query: 8032 DPLSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNG 8211
++N VF+I K S L N+ + SDV +Q + C D
Sbjct: 4178 TYINNRVFKIHKFGHSPLINLTGG---------LSHASDVVLYHQHKQPEVTNPC--DRK 4226
Query: 8212 GCDQLCTVVADDIGLAASKVQCSCNDTYEL-----------VQEPGKDYPTQCVLRGSNS 8358
C+ LC L+ S C+C + L P P C L+ N
Sbjct: 4227 KCEWLCL-------LSPSGPVCTCPNGKRLDNGTCVPVPSPTPPPDAPRPGTCTLQCFNG 4279
Query: 8359 ---------EPAKECLPPY-NFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPE 8508
+P C P Y +C C C + CA +P+ T CP
Sbjct: 4280 GSCFLNARRQPKCRCQPRYTGDKCELDQC---WEYCHNGGTCA----ASPSGMPTCRCPT 4332
Query: 8509 DYN--LCTNRRC 8538
+ CT + C
Sbjct: 4333 GFTGPRCTQQVC 4344
Score = 73.6 bits (179), Expect = 1e-10
Identities = 64/262 (24%), Positives = 111/262 (41%), Gaps = 24/262 (9%)
Frame = +1
Query: 12967 KKIVAGHLQQPTALITAPSAGRICYSD------AGLHAKIECADMDGTHRQIIVKD-LVF 13125
K ++ G + P A++ P G + ++D ++E A MDG+HR I V V
Sbjct: 657 KTLIEGKMTHPRAIVVDPLNGWMYWTDWEEDPKDSRRGRLERAWMDGSHRDIFVTSKTVL 716
Query: 13126 SPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDVFE--NHIYWL 13299
P +++D G R+YWVD Y R++ + ++G++R V + +A + N+++W
Sbjct: 717 WPNGLSLDIPAG-RLYWVDAFYDRIETILLNGTDRKIVYEGPELNHAFGLCHHGNYLFWT 775
Query: 13300 SRESKTLYVQDKFGRG---RVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLC 13470
S ++Y ++ G V++L S+ +R+ + CS LC
Sbjct: 776 EYRSGSVYRLERGVAGAQPTVTLLRSERPPIFEIRMYDAQQQQVGTNKCRVNNGGCSSLC 835
Query: 13471 VSLPSTGFACLCPDGIVPQLDG-SCATQHVEALTMPKQCK-----CTNG------GKCRL 13614
++ P + C C + V DG +C + P QC+ C N KC
Sbjct: 836 LATPGSR-QCACAEDQVLDADGVTCLAN--PSYVPPPQCQPGEFACANNRCIQERWKCDG 892
Query: 13615 DGSCECTSDFEGDQCEKESSVS 13680
D C SD C + + S
Sbjct: 893 DNDCLDNSDEAPALCHQHTCPS 914
Score = 72.8 bits (177), Expect = 2e-10
Identities = 71/311 (22%), Positives = 134/311 (42%), Gaps = 10/311 (3%)
Frame = +1
Query: 2404 MSFDWISKQLYYVDNIRNSLEVVKI-GETGLVHPDELVRRQLITELRD-PVSVVVHPWKG 2577
++ DW++ +Y+ D+ R+ +EV ++ GE R+ LI+ + D P ++VV P +G
Sbjct: 4035 IAIDWVAGNVYWTDSGRDVIEVAQMKGEN---------RKTLISGMIDEPHAIVVDPLRG 4085
Query: 2578 LLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMD 2757
+++++ I +DG + + + P+ +A+D+ RL W D L I +
Sbjct: 4086 TMYWSDWGNHPKIETAAMDGTLRETLVQDNIQWPTGLAVDYHNERLYWADAKLSVIGSIR 4145
Query: 2758 FDGKN-VVKLDIDNPI--PVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADE 2928
+G + +V +D + P +I + +YIY V + ++HK G S ++ G
Sbjct: 4146 LNGTDPIVAVDSKRGLSHPFSIDVFEDYIYGVTYINNRVFKIHK--FGHSPLINLTGGLS 4203
Query: 2929 RSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINK 3108
+ + H+ + +PC +C LC +PS C C G +
Sbjct: 4204 HASDVVLYHQHKQPEV-----TNPCDRKKCEWLCLLSPS-------GPVCTCPNG---KR 4248
Query: 3109 ENNHSCQKDPAEKIEQLCSSNST-QFQCKN-GRCI---PKEWKCDGENDCLDESDEIDEK 3273
+N +C P+ T QC N G C ++ KC + + E+D+
Sbjct: 4249 LDNGTCVPVPSPTPPPDAPRPGTCTLQCFNGGSCFLNARRQPKCRCQPRYTGDKCELDQC 4308
Query: 3274 GDKCFHETECA 3306
+ C + CA
Sbjct: 4309 WEYCHNGGTCA 4319
Score = 67.8 bits (164), Expect = 7e-09
Identities = 43/129 (33%), Positives = 56/129 (43%), Gaps = 19/129 (14%)
Frame = +1
Query: 610 GSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKF------------RCDYYDDCGDN 753
GS+ CA D+ + C AN +CQP +F +CD +DC DN
Sbjct: 840 GSRQCACAEDQVLDADGVTCLANPSYVPPPQCQPGEFACANNRCIQERWKCDGDNDCLDN 899
Query: 754 SDEDE--CGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQ--CSQNLCP--SL 915
SDE C ++ CP ++ C CI LCDG DC + DE CS CP
Sbjct: 900 SDEAPALCHQHTCPSDRFKCE-NNRCIPNRWLCDGDNDCGNSEDESNATCSARTCPPNQF 958
Query: 916 GCQAG-CHP 939
C +G C P
Sbjct: 959 SCASGRCIP 967
Score = 55.1 bits (131), Expect = 5e-05
Identities = 45/210 (21%), Positives = 87/210 (41%), Gaps = 4/210 (1%)
Frame = +1
Query: 13054 LHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERT 13233
LH I A + G + +++ + +P +AID + ++Y+ D +++ DGS R
Sbjct: 2388 LHPSIMRAALSGANVLTLIEKDIRTPNGLAIDH-RAEKLYFSDATLDKIERCEYDGSHRY 2446
Query: 13234 TVVHDRHI-PYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKY 13410
++ + P+ + V+ HI+W + + +K+ + +L D+ ++
Sbjct: 2447 VILKSEPVHPFGLAVYGEHIFWTDWVRRAVQRANKYVGSDMKLLRVDIPQQPMGIIA--V 2504
Query: 13411 AKDTQR-TVSGC--ERAQCSHLCVSLPSTGFACLCPDGIVPQLDGSCATQHVEALTMPKQ 13581
A DT +S C C LC+ C C G + Q D +C + + +
Sbjct: 2505 ANDTNSCELSPCRINNGGCQDLCLLTHQGHVNCSCRGGRILQEDFTCRAMN-SSCRAQDE 2563
Query: 13582 CKCTNGGKCRLDGSCECTSDFEGDQCEKES 13671
+C NG +C+ S + EK S
Sbjct: 2564 FECANGECISFSLTCDGVSHCKDKSDEKPS 2593
Score = 50.8 bits (120), Expect = 0.001
Identities = 41/154 (26%), Positives = 52/154 (33%), Gaps = 28/154 (18%)
Frame = +1
Query: 11239 MSAERNCTAEEFRCNNN-KCIAKAWRXXXXXXXXXXXXETPE-CAQIE---CKKGWTRCS 11403
M A + C+ ++F C + CI+K WR E PE C Q + C C
Sbjct: 22 MDAPKTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEHSCL 81
Query: 11404 SSYRCIPNWAFCNGQDDCRDNSDE-----------DKQRC----------PTCDDVGEFR 11520
+ C+P CNG DC D SDE + C PTC F+
Sbjct: 82 GTELCVPMSRLCNGIQDCMDGSDEGAHCRELRVNCSRMGCQHHCVPTPSGPTCYCNNSFQ 141
Query: 11521 CATSGKCIPRRWMCDTENDCGDNSDELDAS--CG 11616
GK C C D S CG
Sbjct: 142 LQADGKTCKDFDECSVYGTCSQLCTNTDGSFTCG 175
Score = 50.4 bits (119), Expect = 0.001
Identities = 35/106 (33%), Positives = 47/106 (44%), Gaps = 12/106 (11%)
Frame = +1
Query: 11599 LDASCGGTT----RPCSESEFRCNDG-KCIPGSKVCDGTIQCSDGLDES-----QCTLRR 11748
L A G T + CS +F C D CI CDG C DG DE+ Q +R
Sbjct: 13 LSALVAGATMDAPKTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQR 72
Query: 11749 CLPGHRQC-DDGTCIAEHKWCDRKKDCPNAADE-LHCEDVSRRTCS 11880
C P C C+ + C+ +DC + +DE HC ++ R CS
Sbjct: 73 CPPNEHSCLGTELCVPMSRLCNGIQDCMDGSDEGAHCREL-RVNCS 117
Score = 47.0 bits (110), Expect = 0.014
Identities = 31/102 (30%), Positives = 42/102 (40%), Gaps = 10/102 (9%)
Frame = +1
Query: 8746 PIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMN---QQCAQHYVRC-PSG 8913
P C + C + CI CDG DC D +DE C Q+C + C +
Sbjct: 25 PKTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEHSCLGTE 84
Query: 8914 RCIPETWQCDGDNDCSDGWD------ETHTNCTDTAGKKICV 9021
C+P + C+G DC DG D E NC+ + CV
Sbjct: 85 LCVPMSRLCNGIQDCMDGSDEGAHCRELRVNCSRMGCQHHCV 126
Score = 42.4 bits (98), Expect = 0.34
Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 24/96 (25%)
Frame = +1
Query: 4210 DRAGCSFKCHNSPNGPICSCPFGEQLVNKTKCEP----------------ENECLDSSSC 4341
DR C + C SP+GP+C+CP G++L N T C P +C + SC
Sbjct: 4224 DRKKCEWLCLLSPSGPVCTCPNGKRLDNGT-CVPVPSPTPPPDAPRPGTCTLQCFNGGSC 4282
Query: 4342 --------SQRCKDEKHGFTCSCDEGYELDVDKRTC 4425
RC+ G C D+ +E + TC
Sbjct: 4283 FLNARRQPKCRCQPRYTGDKCELDQCWEYCHNGGTC 4318
>gi|9055270|ref|NP_061027.1| low density lipoprotein-related protein 1B;
low density lipoprotein receptor related protein-deleted
in tumor [Homo sapiens]
gi|46577130|sp|Q9NZR2|LR1B_HUMAN Low-density lipoprotein
receptor-related protein 1B precursor (Low-density
lipoprotein receptor-related protein-deleted in tumor)
(LRP-DIT)
gi|7861733|gb|AAF70379.1| low density lipoprotein receptor related
protein-deleted in tumor [Homo sapiens]
Length = 4599
Score = 1881 bits (4873), Expect = 0.0
Identities = 1356/4534 (29%), Positives = 2073/4534 (44%), Gaps = 202/4534 (4%)
Frame = +1
Query: 667 CTANEFQCKNK-RCQPRKFRCDYYDDCGDNSDE--DECGE---YRCPPGKWNCPGTGHCI 828
C EF C + C + + CD DC D+SDE D C E +CP C GT C+
Sbjct: 32 CDPGEFLCHDHVTCVSQSWLCDGDPDCPDDSDESLDTCPEEVEIKCPLNHIACLGTNKCV 91
Query: 829 DQLKLCDGSKDCADGADEQQCSQNL---CPSLGCQAGCHPSPHGGECTCPSGYKLDDRFH 999
+LC+G DC DG DE Q L C L CQ C + C C G+++ +
Sbjct: 92 HLSQLCNGVLDCPDGYDEGVHCQELLSNCQQLNCQYKCTMVRNSTRCYCEDGFEITED-G 150
Query: 1000 RTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRG---YCVSN 1170
R+C D +ECA +G C Q C N +TCSC+ + + +Q ++ K + +
Sbjct: 151 RSCKDQDECAVYGTCSQTCRNTHGSYTCSCV-EGYLMQPDNRSCKAKIEPTDRPPILLIA 209
Query: 1171 NADKMKLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFS 1350
N + +++F + L+ N +E I+ +DF Y + I W + S
Sbjct: 210 NFETIEVFYLNGSKMATLSSVNGNE----------IHTLDFIYNEDMICWIE-------S 252
Query: 1351 ADVDDEGEISQIKKLS----------LKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSY 1500
+ ++ + QI K L+S + +A+DW+T LY ++ RI V +
Sbjct: 253 RESSNQLKCIQITKAGGLTDEWTINILQSFHNVQQMAIDWLTRNLYFVDHVGDRIFVCNS 312
Query: 1501 DGERRTVLLADGLTLPLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQV 1671
+G L+ L P IA+DP+ G++FFT N K+E MDG NR ++++ T Q
Sbjct: 313 NGSVCVTLIDLELHNPKAIAVDPIAGKLFFTDYGNVAKVERCDMDGMNRTRIIDSKTEQP 372
Query: 1672 SGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDW 1851
+ + +D+ K VYWVD +D + +DYQG +R V QG V H +G+ +F+ YLY T+
Sbjct: 373 AALALDLVNKLVYWVDLYLDYVGVVDYQGKNRHTVIQGRQV-RHLYGITVFEDYLYATNS 431
Query: 1852 TRLGVIQVEKF-GSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNA 2028
++++ +F G+D L EN GI Y QP C P
Sbjct: 432 DNYNIVRINRFNGTDIHSL-IKIEN---AWGIRIYQKRTQPTVRSHACEVDPYGMP---G 484
Query: 2029 DCEGMCILSKDNGGFGVGYK---CACPIGQKL-VNGKRCIDSIDYLLFSSNK----IVRG 2184
C +C+LS YK C C G L +G+ C + L K IVRG
Sbjct: 485 GCSHICLLSSS-------YKTRTCRCRTGFNLGSDGRSCKRPKNELFLFYGKGRPGIVRG 537
Query: 2185 IFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGA 2364
+ ++N K E ++PI + R + F E N ++AD I R + DG
Sbjct: 538 M--DLNTKIADEYMIPIENLVNPR-ALDFHAET----NYIYFADTTSFLIGRQKIDGTER 590
Query: 2365 APVLVTHNDGLFSMSFDWISKQLYYV-DNIRNSLEVVKIGETGLVHPDELVRRQLITELR 2541
+L D + ++ DWI LY+ D R ++ V ++ + + + L E+
Sbjct: 591 ETILKDDLDNVEGIAVDWIGNNLYWTNDGHRKTINVARLEKAS-----QSRKTLLEGEMS 645
Query: 2542 DPVSVVVHPWKGLLFYAEAMRP------AAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFA 2703
P +VV P G +++ + I + +DG N Q+ + + P+ + +DF
Sbjct: 646 HPRGIVVDPVNGWMYWTDWEEDEIDDSVGRIEKAWMDGFNRQIFVTSKMLWPNGLTLDFH 705
Query: 2704 ENRLCWGDTLLKTISCMDFDG--KNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVH 2877
N L W D I + +G + +V + P ++ Y+++ SI ++
Sbjct: 706 TNTLYWCDAYYDHIEKVFLNGTHRKIVYSGRELNHPFGLSHHGNYVFWTDYMNGSIFQLD 765
Query: 2878 KKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQ--CTQLCFATPSES 3051
+ + E +F L+ + Q ++ CR + C+ LC A P
Sbjct: 766 LITSEVTLLRHE----RPPLFGLQIYDPRKQ-----QGDNMCRVNNGGCSTLCLAIPGGR 816
Query: 3052 HPNELEAKCACRQGFMINKENNHSCQKDPAEKIEQLCSSNSTQFQCKNGRCIPKEWKCDG 3231
CAC +++ EN +C +P E + +C + +F+CKN CI WKCDG
Sbjct: 817 -------VCACADNQLLD-ENGTTCTFNPGEALPHICKAG--EFRCKNRHCIQARWKCDG 866
Query: 3232 ENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKY 3411
++DCLD SDE +++ C N
Sbjct: 867 DDDCLDGSDE----------------DSVNCFNHS------------------------- 885
Query: 3412 CKDGQKPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNATCAANQFSCANG 3591
C D Q F+C N+RCIP++W E + C TC +QFSC NG
Sbjct: 886 CPDDQ--------FKCQNNRCIPKRWLCDGANDCGSNEDESNQTCTARTCQVDQFSCGNG 937
Query: 3592 RCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSAL-QFRCANGRQCVPLRNHXXXXXXXXX 3768
RCIP WLCD ++DC D TDE C C L QF C +GR C+ + H
Sbjct: 938 RCIPRAWLCDREDDCGDQTDE-MASCEFPTCEPLTQFVCKSGR-CISSKWHCDSDDDCGD 995
Query: 3769 XXXXXXXAVTAESCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCT-----SGR 3933
SC +QF+C SSG CIP W SDE + CT S
Sbjct: 996 GSDEVG---CVHSCFDNQFRC-SSGRCIPGHWACDGDNDCGDFSDEAQINCTKEEIHSPA 1051
Query: 3934 QCSSDQFKCG-NGRCILNNWLCDGENDCGDGSDESSERG--------------------- 4047
C+ ++F+C +G C+ + W CDGE DC DGSDE G
Sbjct: 1052 GCNGNEFQCHPDGNCVPDLWRCDGEKDCEDGSDEKGCNGTIRLCDHKTKFSCWSTGRCIN 1111
Query: 4048 ----------CKTSMNARKC------PFEHVACENDQETCIPLHQLCDGKTHCPGGTDEG 4179
C+ + C P +H C ND C+ +LC+GK CP G+DEG
Sbjct: 1112 KAWVCDGDIDCEDQSDEDDCDSFLCGPPKH-PCANDTSVCLQPEKLCNGKKDCPDGSDEG 1170
Query: 4180 GRCARDLCSADRAGCSFKCHNSPN-GPICSCPFGEQLVNKTK-CEPENECLDSSSCSQRC 4353
C D CS + GCS C P G +CSCP G QL K CE + C + CSQ C
Sbjct: 1171 YLC--DECSLNNGGCSNHCSVVPGRGIVCSCPEGLQLNKDNKTCEIVDYCSNHLKCSQVC 1228
Query: 4354 KDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGAIV 4533
+ KH CSC EG++LDVD +C D + I+ S R+ I D ++ +
Sbjct: 1229 EQHKHTVKCSCYEGWKLDVDGESCTSVDPFEAFIIF-SIRHEIRRIDLHKRDYSLLVPGL 1287
Query: 4534 ENAIALAWDSLTDRIYWSDIREKKI----LSANRNGTNATVFIADGLDITEGIALDWVGR 4701
N IAL + +YW+D+ E +I LS + + V + GL EG+ +DW+
Sbjct: 1288 RNTIALDFHFNQSLLYWTDVVEDRIYRGKLSESGGVSAIEVVVEHGLATPEGLTVDWIAG 1347
Query: 4702 NLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQN-PCIER 4878
N+YW+DS+L+ IEVA L D RT L+ + PR IA+DPR G++FWTDW N P IE
Sbjct: 1348 NIYWIDSNLDQIEVAKL-DGSLRTTLIAGAMEHPRAIALDPRYGILFWTDWDANFPRIES 1406
Query: 4879 ASMDGTDRQIIVKTKIY--WPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASS 5052
ASM G R+ I K WPN + +D+ R+ + D++ D I YDG+ +++
Sbjct: 1407 ASMSGAGRKTIYKDMKTGAWPNGLTVDHFEKRIVWTDARSDAIYSALYDGTNMIEIIRGH 1466
Query: 5053 KFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQP 5232
+++ HP A++++ +Y++D R L K+ G T ++ + HP QP
Sbjct: 1467 EYLSHPFAVSLYGSEVYWTDWRTNTLSKANKW-TGQNVSVIQKTSAQPFDLQIYHPSRQP 1525
Query: 5233 VIKNNPCSTN----PCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTN 5400
N PC+ N PCSH+CL+N+ + C CP KL + K C + K FL+ +++
Sbjct: 1526 QAPN-PCAANDGKGPCSHMCLINHNRSAACACPHLMKLSSDKKTCYE-MKKFLLYARRSE 1583
Query: 5401 VFGIEMNSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDS 5580
+ G+++++ + A VP + + +DA E ++ + I T +
Sbjct: 1584 IRGVDIDNPYFNF--ITAFTVP--DIDDVTVIDFDASEERLYWTD----------IKTQT 1629
Query: 5581 AIYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLV-VGNKITQT-IEIIRTQGKQYRS 5754
I R+ +NG + S + L DW RNL + ++ +T I + R G S
Sbjct: 1630 -IKRAFINGTGLETVISRDI-QSIRGLAVDWVSRNLYWISSEFDETQINVARLDGSLKTS 1687
Query: 5755 VILSNDQSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLA 5934
+I D+ +G ++W D + A +DGSN ++ N
Sbjct: 1688 IIHGIDKPQCLAAHPV-------RGKLYWTDGN------TINMANMDGSNSKILFQNQKE 1734
Query: 5935 ELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYV--LSDGGRQPNGLAFYGDRLFYA 6108
+ ++ID ++Y+ + G I+ DG + + + + + L +L++A
Sbjct: 1735 PVG-LSIDYVENKLYWISSGNGTINRCNLDGGNLEVIESMKEELTKATALTIMDKKLWWA 1793
Query: 6109 DSAFDSIEVATINGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHINNGNCDHICI 6288
D + + P T + + ++K A + C +NNG C +C+
Sbjct: 1794 DQNLAQLGTCSKRDGRNP---TILRNKTSGVVHMKVYDKEAQQGSNSCQLNNGGCSQLCL 1850
Query: 6289 PLMFAQRTCTCANGY-VKDGQTSCKLFDESFVIVATKTKVIGYPIDETQSKGVAMEPIGG 6465
P RTC C GY ++ + SC+ ESF++ + + G P+ E K A+ PI G
Sbjct: 1851 PTSETTRTCMCTVGYYLQKNRMSCQGI-ESFLMYSVHEGIRGIPL-EPSDKMDALMPISG 1908
Query: 6466 LSIT-GVDYDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWIN 6642
S G+D+ E+ TIY + G NK I+ ++ +I + +G ++ +A+DWI
Sbjct: 1909 TSFAVGIDFHAENDTIYWTDM-GFNK-ISRAKRDQTWKEDIITNGLGR--VEGIAVDWIA 1964
Query: 6643 YNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQ 6822
N+Y+ +H IEV++L+G++R ++++ + P SIAV P L+W + GQ P I
Sbjct: 1965 GNIYWTDHGFNL--IEVARLNGSFRYVIISQGLDQPRSIAVHPEKGLLFWTEWGQMPCIG 2022
Query: 6823 RSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVR-STGGTPELVRSDI 6999
++ LDGS + V+VS GIA P + +D +YW DA+ D I R+ TGG E+V S
Sbjct: 2023 KARLDGSEKVVLVSMGIAWPNGISIDYEENKLYWCDARTDKIERIDLETGGNREMVLSGS 2082
Query: 7000 -ASAAGVALHGQNMYWTDN-RLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSN 7173
VA+ G +YW+D R K + T + T + +LK+ V +F+
Sbjct: 2083 NVDMFSVAVFGAYIYWSDRAHANGSVRRGHKNDATETITMRTGLGVNLKE---VKIFNRV 2139
Query: 7174 NQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCARGVLK--GRTCEEPDTYIMFSD 7347
+ + ++ C DN C QLC G TC+CA G L G TC + Y+++S
Sbjct: 2140 RE-KGTNVCA-RDN---GGCKQLCLYR-GNSRRTCACAHGYLAEDGVTCLRHEGYLLYSG 2193
Query: 7348 GDKIIDVAIEPDVKASRPLKDPFPE---ISNLQTFDVDVNLRRVYFVVESPVGVNISWFS 7518
+ + + + + P++ P+ N+ D N RR G N ++S
Sbjct: 2194 RTILKSIHLSDETNLNSPIR-PYENPRYFKNVIALAFDYNQRRK--------GTNRIFYS 2244
Query: 7519 MNNAENPRLVFG--ASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVM--AIDTAG-- 7680
+ N +L+ +Q + + + + +Y+T+ + +D
Sbjct: 2245 DAHFGNIQLIKDNWEDRQVIVENVGSVEGLAYHRAWDTLYWTSSTTSSITRHTVDQTRPG 2304
Query: 7681 ----EHLSTIASGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIV 7848
E + T++ D + LA+D C L+FW T+ P I RS L G + +V+V
Sbjct: 2305 AFDREAVITMSEDDHPHVLALDECQNLMFW------TNWNEQHPSIMRSTLTGKNAQVVV 2358
Query: 7849 SESISLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGYRAK--SLDIWDRWL 8022
S I P + +D+R +K+Y++D + IE +YDG R VI SL ++D ++
Sbjct: 2359 STDILTPNGLTIDYRAEKLYFSDGSLGKIERCEYDGSQRHVIVKSGPGTFLSLAVYDNYI 2418
Query: 8023 YMSDPLSNGVFRIDKESGSGLENVVSDRRIPGA-LRVFASESDVRTRNQVCNALTSQLCK 8199
+ SD + R +K +G + + SD IP + + A +D N+ C
Sbjct: 2419 FWSDWGRRAILRSNKYTGGDTKILRSD--IPHQPMGIIAVANDT-------NSCELSPCA 2469
Query: 8200 TDNGGCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSEPAKECL 8379
NGGC LC + + +V CSC L+++ +CV + S+ E
Sbjct: 2470 LLNGGCHDLCLLTPN------GRVNCSCRGDRILLED------NRCVTKNSSCNAYSE-- 2515
Query: 8380 PPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKC 8559
F+CG+G CI TCD P C D SDE YC RSC + C NRRCI K C
Sbjct: 2516 ----FECGNGECIDYQLTCDGIPHCKDKSDEKLLYCENRSCRRGFKPCYNRRCIPHGKLC 2571
Query: 8560 NHIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCP 8739
+ +DCGD SDELDC + CA F C++G CI ++ C+ + DC D SDE C
Sbjct: 2572 DGENDCGDNSDELDCKVST-CATVEFRCADGTCIPRSARCNQNIDCAD--ASDEK--NCN 2626
Query: 8740 GLPIDCR-----GVK----VRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQ-QCAQ 8889
DC GVK +RC +T++C+ P +CDG +DCGD +DE + N+ +C +
Sbjct: 2627 NT--DCTHFYKLGVKTTGFIRCNSTSLCVLPTWICDGSNDCGDYSDELKCPVQNKHKCEE 2684
Query: 8890 HYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRA 9069
+Y CPSGRCI TW CDG DC DG DE H + + + + F C KCIS+
Sbjct: 2685 NYFSCPSGRCILNTWICDGQKDCEDGRDEFHCDSSCSWNQ--------FACSAQKCISKH 2736
Query: 9070 FIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCA 9249
+I S CG TC F C Q C+PR WLCDG+ C
Sbjct: 2737 WICDGEDDCGDGLD-ESDSICGAITCAADMFSC-------QGSRACVPRHWLCDGERDCP 2788
Query: 9250 GGEDESTELCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPD 9429
G DE + C++ F C N+ CI + CD D+DC DGSDE C Y C +
Sbjct: 2789 DGSDELSTAGCAPNNTCDENAFMCHNKVCIPKQFVCDHDDDCGDGSDESPQCGYRQCGTE 2848
Query: 9430 FFQCANHKCVPNS-WKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTSGECIDD 9606
F CA+ +C+ N+ W+CDG+ DC D SDE P N C++ F C +G CI
Sbjct: 2849 EFSCADGRCLLNTQWQCDGDFDCPDHSDE--APLNPKCKSAEQSCNSSFFMCKNGRCIPS 2906
Query: 9607 AKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQK 9786
+CD DC D SDE + C I+EC + C Q C D+ + YKC C+ GF + D K
Sbjct: 2907 GGLCDNKDDCGDGSDERN-CHINECLSKKVSGCSQDCQDLPVSYKCKCWPGFQLK-DDGK 2964
Query: 9787 SCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKH 9966
+C +++EC G CSQ+C + G+YKC C DGY++ D+ + ++ + EPF +LA+ H
Sbjct: 2965 TCVDIDECSSGFP-CSQQCINTYGTYKCLCTDGYEIQPDNPNGCKSLSDEEPFLILADHH 3023
Query: 9967 YIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYE 10146
IRKIS DG+ Y L QG +NV+++D D E+ Y ID + R++ L+ +
Sbjct: 3024 EIRKISTDGSNYTLLKQGLNNVIAIDFDYREEFIYWIDSSRPNGSRIN----RMCLNGSD 3079
Query: 10147 TVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHP 10326
+ HN +AVDW+G+ LY + ++R I V +L+G + L+ R++ P+ + + P
Sbjct: 3080 IKVVHNTAVPNALAVDWIGKNLYWSDTEKRIIEVSKLNGLYPTILVSKRLKFPRDLSLDP 3139
Query: 10327 GKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAH 10506
GYL++ + P+IGR+ +DG+ + + E + P A+ IDY + RL+W D
Sbjct: 3140 QAGYLYWIDCCEYPHIGRVGMDGTNQ-----SVVIETKISRPMALTIDYVNRRLYWADE- 3193
Query: 10507 LNEIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILK 10686
N I F + DG+ R +P Q V ++ +F+DY+YW D + + R K +G + L
Sbjct: 3194 -NHIEFSNMDGSHRHKVPNQDIPGVIALTLFEDYIYWTDGKTKSLSRAHKTSGADRLSLI 3252
Query: 10687 KTVQLPNDLRIVHPMRQP-AYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQK 10863
+ D+++ H RQP + C NNGGCSHLCL+ A G +TC+CP F L +D +
Sbjct: 3253 YSWHAITDIQVYHSYRQPDVSKHLCMINNGGCSHLCLL-APGKTHTCACPTNFYLAADNR 3311
Query: 10864 TCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNH 11043
TC NCT QF C D KCIP W CD DC DGSDEP + C + C G FQC
Sbjct: 3312 TCLSNCTASQFRCKTD--KCIPFWWKCDTVDDCGDGSDEPDD--CPEFRCQPGRFQCGTG 3367
Query: 11044 NCTRPFQIXXXXXXXXXXXXEQNCD-KACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSD 11220
C P I E NCD C FKC +CIP D
Sbjct: 3368 LCALPAFICDGENDCGDNSDELNCDTHVCLSGQFKCTKNQKCIPVNLRCNGQDDCGDEED 3427
Query: 11221 EADTLCMSAERNCTAEEFRCNNNK-CIAKAWRXXXXXXXXXXXXETPECAQIECKKGWTR 11397
E D E +C+ + F+C K CI+K W E C + C +
Sbjct: 3428 ERD----CPENSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEA-NCDKKTCGPHEFQ 3482
Query: 11398 CSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMCDTEND 11577
C ++ CIP+ C+ Q+DC DNSDE+ + TC + +F CA +G C+ R+ CD + D
Sbjct: 3483 CKNN-NCIPDHWRCDSQNDCSDNSDEENCKPQTC-TLKDFLCA-NGDCVSSRFWCDGDFD 3539
Query: 11578 CGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQ-------- 11733
C D SDE + CS+ +FRC++G+CIP CDG C G DE
Sbjct: 3540 CADGSDERNCETS-----CSKDQFRCSNGQCIPAKWKCDGHEDCKYGEDEKSCEPASPTC 3594
Query: 11734 ------CTLRRCLP------GHRQCDDGT----CIAEHK----------------W-CDR 11814
C C+ G C DG+ C+ E K W CD
Sbjct: 3595 SSREYICASDGCISASLKCNGEYDCADGSDEMDCVTECKEDQFRCKNKAHCIPIRWLCDG 3654
Query: 11815 KKDCPNAADELHCEDVSRRTCSPFEFECANSVCIPRKFMXXXXXXXXXXSDETSSECRSA 11994
DC + +DE +CE C EF C NS+C ++ SDE C
Sbjct: 3655 IHDCVDGSDEENCER-GGNICRADEFLCNNSLCKLHFWVCDGEDDCGDNSDEAPDMCVKF 3713
Query: 11995 QCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSFSEY--GDCSSDQFKC 12168
C RC ++R+CL Q+CNG ++CG N D C Y C D+F C
Sbjct: 3714 LCPSTRPHRCRNNRICLQSEQMCNGIDECGDNSDEDH----CGGKLTYKARPCKKDEFAC 3769
Query: 12169 ANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKHICTDVRDGFYCHC 12348
+N KC+ + CDR DDCGD SDE GC + +CE N G C ++ +C C
Sbjct: 3770 SNKKCIPMDLQCDRLDDCGDGSDEQGCRIAPTEYTCEDNVNPCGDDAYCNQIKTSVFCRC 3829
Query: 12349 RDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCR 12528
+ GF+ + ++ ++C D++EC TC+ C+N +GSY C C ++++ C
Sbjct: 3830 KPGFQRNMKN-RQCEDLNECLVFGTCSHQCINVEGSYKCVCDQNFQER-------NNTCI 3881
Query: 12529 AKGDAANVM-IGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGS 12705
A+G V+ I D ++ + + H +++++ W
Sbjct: 3882 AEGSEDQVLYIANDTDILGFIYPFNYSGDHQQISHIEHNSRITGMDVYYQRDMIIW---- 3937
Query: 12706 ERTIYRSAIANGNQSHEGQKLDVDFAAMGVV------PTAIAVDYTTGNLFIAAVSENIE 12867
T + + H +K A G++ P IAVD+ GN++ S
Sbjct: 3938 -STQFNPGGIFYKRIHGREKRQ---ANSGLICPEFKRPRDIAVDWVAGNIYWTDHSRMHW 3993
Query: 12868 NGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSD 13047
T + I N G + +G +++ +P A+ P G + ++
Sbjct: 3994 FSYYTTHWTSLRYSI---NVGQL-----NGPNCTRLLTNMAGEPYAIAVNPKRGMMYWTV 4045
Query: 13048 AGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSE 13227
G H+ IE A MDGT R+I+V+ + PT +A+D RIYW D + + +V DGS
Sbjct: 4046 VGDHSHIEEAAMDGTLRRILVQKNLQRPTGLAVDY-FSERIYWADFELSIIGSVLYDGSN 4104
Query: 13228 RTTVVHDRH---IPYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRV 13398
V + P+ +D+FE++IY ++ VQ KFG G V LA +++ V +
Sbjct: 4105 SVVSVSSKQGLLHPHRIDIFEDYIYGAGPKNGVFRVQ-KFGHGSVEYLALNIDKTKGVLI 4163
Query: 13399 SQKYAKDTQRTVSGCERAQCSHLCVSLPSTGFACLCPDGIVPQLDGSCATQHVEALTMPK 13578
S +Y + + C C LC+ PS G C+CP+G ++G+C + +
Sbjct: 4164 SHRYKQ--LDLPNPCLDLACEFLCLLNPS-GATCVCPEGKY-LINGTCNDDSL----LDD 4215
Query: 13579 QCK--CTNGGKCRL----DGSCECTSDFEGDQCE 13662
CK C NGG+C L D C C + G++CE
Sbjct: 4216 SCKLTCENGGRCILNEKGDLRCHCWPSYSGERCE 4249
Score = 364 bits (934), Expect = 4e-98
Identities = 284/1074 (26%), Positives = 458/1074 (42%), Gaps = 75/1074 (6%)
Frame = +1
Query: 133 SVNTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPG--CKSDQ------ 288
SVN + C ++ F+C + +CI W C+ DQ
Sbjct: 878 SVNCFNHSCPDDQFKCQNNRCIPKRWLCDGANDCGSNEDESNQTCTARTCQVDQFSCGNG 937
Query: 289 ------WQCD------------------------TYTWHSVSCIAEYQRCDNITDCADGS 378
W CD + S CI+ CD+ DC DGS
Sbjct: 938 RCIPRAWLCDREDDCGDQTDEMASCEFPTCEPLTQFVCKSGRCISSKWHCDSDDDCGDGS 997
Query: 379 DEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKD-SCSRNH----TA 543
DE C S D N F C+ GR C CDG DC D SDE +C++
Sbjct: 998 DEVGCVHSCFD----NQFRCSSGR-CIPGHWACDGDNDCGDFSDEAQINCTKEEIHSPAG 1052
Query: 544 CFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPD------TCEFKKCTANEFQC-KNKR 702
C +F+C C+ W CDG KDC DGSDE C+ K +F C R
Sbjct: 1053 CNGNEFQCHPDGNCVPDLWRCDGEKDCEDGSDEKGCNGTIRLCDHK----TKFSCWSTGR 1108
Query: 703 CQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPG-TGHCIDQLKLCDGSKDCADGAD 879
C + + CD DC D SDED+C + C P K C T C+ KLC+G KDC DG+D
Sbjct: 1109 CINKAWVCDGDIDCEDQSDEDDCDSFLCGPPKHPCANDTSVCLQPEKLCNGKKDCPDGSD 1168
Query: 880 E----QQCSQNLCPSLGCQAGCHPSP-HGGECTCPSGYKLDDRFHRTCSDINECAEFGYC 1044
E +CS N + GC C P G C+CP G +L ++ ++TC ++ C+ C
Sbjct: 1169 EGYLCDECSLN---NGGCSNHCSVVPGRGIVCSCPEGLQL-NKDNKTCEIVDYCSNHLKC 1224
Query: 1045 DQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRL 1224
Q+C H+ CSC + + L ++ G+ C S + + + + R + R+
Sbjct: 1225 SQVCEQHKHTVKCSCY-EGWKLDVD---GES-------CTSVDPFEAFIIFSIRHEIRRI 1273
Query: 1225 NPKNPDEEVKKLASG-EFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSL 1401
+ D + L G +DF + ++WTD + + + + G +S I+ +
Sbjct: 1274 DLHKRDYSL--LVPGLRNTIALDFHFNQSLLYWTDVVEDRIYRGKLSESGGVSAIEVVVE 1331
Query: 1402 KSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGE 1581
L P L VDWI +Y I+S +I+V+ DG RT L+A + P IALDP G
Sbjct: 1332 HGLATPEGLTVDWIAGNIYWIDSNLDQIEVAKLDGSLRTTLIAGAMEHPRAIALDPRYGI 1391
Query: 1582 MFFT----NQLKLEAAAMDGTNRRTLVNTHTHQV--SGIVVDITAKRVYWVDPKVDRLES 1743
+F+T N ++E+A+M G R+T+ +G+ VD KR+ W D + D + S
Sbjct: 1392 LFWTDWDANFPRIESASMSGAGRKTIYKDMKTGAWPNGLTVDHFEKRIVWTDARSDAIYS 1451
Query: 1744 IDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKF-GSDTKLLWSNTE 1920
Y G + + +G + HPF ++L+ +YWTDW + + K+ G + ++ +
Sbjct: 1452 ALYDGTNMIEIIRGHEYLSHPFAVSLYGSEVYWTDWRTNTLSKANKWTGQNVSVI---QK 1508
Query: 1921 NNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNAD----CEGMCILSKDNGGFGVGYK 2088
+ P + YHP QP + NPC D C MC+++ +
Sbjct: 1509 TSAQPFDLQIYHPSRQP----------QAPNPCAANDGKGPCSHMCLINHNRSA-----A 1553
Query: 2089 CACPIGQKLVNGKR-CIDSIDYLLFSSNKIVRGI---FPEINEKALAEAVLPISPISQRR 2256
CACP KL + K+ C + +LL++ +RG+ P N I+ +
Sbjct: 1554 CACPHLMKLSSDKKTCYEMKKFLLYARRSEIRGVDIDNPYFNF---------ITAFTVPD 1604
Query: 2257 IGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWISKQLY 2436
I ++ D ++ DI TI R +G G V+ + ++ DW+S+ LY
Sbjct: 1605 IDDVTVIDFDASEERLYWTDIKTQTIKRAFINGTGLETVISRDIQSIRGLAVDWVSRNLY 1664
Query: 2437 YVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKGLLFYAEAMRPAAI 2616
++ + + ++ + D ++ +I + P + HP +G L++ + I
Sbjct: 1665 WISSEFDETQI------NVARLDGSLKTSIIHGIDKPQCLAAHPVRGKLYWTDG---NTI 1715
Query: 2617 YRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKN---VVKLD 2787
++DG N +++ P ++ID+ EN+L W + TI+ + DG N + +
Sbjct: 1716 NMANMDGSNSKILFQNQ-KEPVGLSIDYVENKLYWISSGNGTINRCNLDGGNLEVIESMK 1774
Query: 2788 IDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQN 2967
+ A+TIM++ +++ Q + K++G I+R + +K +
Sbjct: 1775 EELTKATALTIMDKKLWWADQNLAQLGTCSKRDGRNPTILRN---KTSGVVHMKVYDKEA 1831
Query: 2968 QPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINKENNHSCQ 3129
Q S C+QLC T +E C C G+ + K N SCQ
Sbjct: 1832 Q---QGSNSCQLNNGGCSQLCLPT------SETTRTCMCTVGYYLQK-NRMSCQ 1875
Score = 283 bits (723), Expect = 1e-73
Identities = 211/762 (27%), Positives = 316/762 (40%), Gaps = 83/762 (10%)
Frame = +1
Query: 139 NTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHS 318
N C DF C +G C+ + + C DQ++C +
Sbjct: 3509 NCKPQTCTLKDFLCANGDCVSSRFWCDGDFDCADGSDERNC-ETSCSKDQFRCS-----N 3562
Query: 319 VSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCR 498
CI +CD DC G DEK C ++ CSS+ +DG C S KC+G+YDC
Sbjct: 3563 GQCIPAKWKCDGHEDCKYGEDEKSCEPASPTCSSREYICASDG--CISASLKCNGEYDCA 3620
Query: 499 DLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEF--KKCT 672
D SDE D T C + QFRC +K CI W+CDG DC DGSDE + CE C
Sbjct: 3621 DGSDEMDCV----TECKEDQFRCKNKAHCIPIRWLCDGIHDCVDGSDE-ENCERGGNICR 3675
Query: 673 ANEFQCKNKRCQPRKFRCDYYDDCGDNSDE--DECGEYRCPPGK-WNCPGTGHCIDQLKL 843
A+EF C N C+ + CD DDCGDNSDE D C ++ CP + C C+ ++
Sbjct: 3676 ADEFLCNNSLCKLHFWVCDGEDDCGDNSDEAPDMCVKFLCPSTRPHRCRNNRICLQSEQM 3735
Query: 844 CDGSKDCADGADEQQCSQNL-------------CPSLGC------------------QAG 930
C+G +C D +DE C L C + C + G
Sbjct: 3736 CNGIDECGDNSDEDHCGGKLTYKARPCKKDEFACSNKKCIPMDLQCDRLDDCGDGSDEQG 3795
Query: 931 C-----------HPSPHGGE-----------CTCPSGYKLDDRFHRTCSDINECAEFGYC 1044
C + +P G + C C G++ + + +R C D+NEC FG C
Sbjct: 3796 CRIAPTEYTCEDNVNPCGDDAYCNQIKTSVFCRCKPGFQRNMK-NRQCEDLNECLVFGTC 3854
Query: 1045 DQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGY-CVSNNADKMKLFVARREGL-- 1215
C N + C C N R C++ ++ L++A +
Sbjct: 3855 SHQCINVEGSYKCVC--------------DQNFQERNNTCIAEGSEDQVLYIANDTDILG 3900
Query: 1216 --YRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSA-FSADVDDEGEISQI 1386
Y N +++ + I G+D Y I W+ + F + +
Sbjct: 3901 FIYPFNYSGDHQQISHIEHNSRITGMDVYYQRDMIIWSTQFNPGGIFYKRIHGREKRQAN 3960
Query: 1387 KKLSLKSLVYPRCLAVDWITNTLYIIESGSRR---------------IDVSSYDGERRTV 1521
L PR +AVDW+ +Y + I+V +G T
Sbjct: 3961 SGLICPEFKRPRDIAVDWVAGNIYWTDHSRMHWFSYYTTHWTSLRYSINVGQLNGPNCTR 4020
Query: 1522 LLADGLTLPLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDI 1692
LL + P IA++P RG M++T + +E AAMDGT RR LV + + +G+ VD
Sbjct: 4021 LLTNMAGEPYAIAVNPKRGMMYWTVVGDHSHIEEAAMDGTLRRILVQKNLQRPTGLAVDY 4080
Query: 1693 TAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQ 1872
++R+YW D ++ + S+ Y G++ + + HP + +F+ Y+Y + GV +
Sbjct: 4081 FSERIYWADFELSIIGSVLYDGSNSVVSVSSKQGLLHPHRIDIFEDYIYGAG-PKNGVFR 4139
Query: 1873 VEKFG-SDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCI 2049
V+KFG + L N + G+ H Q + + NPC + CE +C+
Sbjct: 4140 VQKFGHGSVEYLALNIDKT---KGVLISHRYKQ----------LDLPNPCLDLACEFLCL 4186
Query: 2050 LSKDNGGFGVGYKCACPIGQKLVNGKRCIDSIDYLLFSSNKI 2175
L+ G C CP G+ L+NG C D D LL S K+
Sbjct: 4187 LNPS------GATCVCPEGKYLING-TCND--DSLLDDSCKL 4219
Score = 283 bits (723), Expect = 1e-73
Identities = 197/673 (29%), Positives = 305/673 (45%), Gaps = 25/673 (3%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKS--DQWQCDTY-TWHSVSC 327
C EN F C G+CI W C+ D++ CD+ +W+ +C
Sbjct: 2682 CEENYFSCPSGRCILNTWICDG--------------QKDCEDGRDEFHCDSSCSWNQFAC 2727
Query: 328 -----IAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYD 492
I+++ CD DC DG DE D + C++ ++F C R C CDG+ D
Sbjct: 2728 SAQKCISKHWICDGEDDCGDGLDESDSICGAITCAA-DMFSCQGSRACVPRHWLCDGERD 2786
Query: 493 CRDLSDEKDS--CSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKK 666
C D SDE + C+ N+T C + F C +K CI K +VCD DC DGSDE C +++
Sbjct: 2787 CPDGSDELSTAGCAPNNT-CDENAFMCHNKV-CIPKQFVCDHDDDCGDGSDESPQCGYRQ 2844
Query: 667 CTANEFQCKNKRC-QPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGT------GHC 825
C EF C + RC +++CD DC D+SDE +C + +C + G C
Sbjct: 2845 CGTEEFSCADGRCLLNTQWQCDGDFDCPDHSDEAPLNP-KCKSAEQSCNSSFFMCKNGRC 2903
Query: 826 IDQLKLCDGSKDCADGADEQQCSQNLCPS---LGCQAGCHPSPHGGECTCPSGYKLDDRF 996
I LCD DC DG+DE+ C N C S GC C P +C C G++L D
Sbjct: 2904 IPSGGLCDNKDDCGDGSDERNCHINECLSKKVSGCSQDCQDLPVSYKCKCWPGFQLKDD- 2962
Query: 997 HRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNA 1176
+TC DI+EC+ C Q C N + C C D + +Q ++ G C S +
Sbjct: 2963 GKTCVDIDECSSGFPCSQQCINTYGTYKCLCT-DGYEIQPDNPNG---------CKSLSD 3012
Query: 1177 DKMKLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTD--RLAHSAFS 1350
++ L +A + +++ + + K I IDFDY + I+W D R S +
Sbjct: 3013 EEPFLILADHHEIRKISTDGSNYTLLKQGLNNVI-AIDFDYREEFIYWIDSSRPNGSRIN 3071
Query: 1351 ADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLA 1530
+ +I + ++ P LAVDWI LY ++ R I+VS +G T+L++
Sbjct: 3072 RMCLNGSDIKVVHNTAV-----PNALAVDWIGKNLYWSDTEKRIIEVSKLNGLYPTILVS 3126
Query: 1531 DGLTLPLDIALDPLRGEMFFTNQLK---LEAAAMDGTNRRTLVNTHTHQVSGIVVDITAK 1701
L P D++LDP G +++ + + + MDGTN+ ++ T + + +D +
Sbjct: 3127 KRLKFPRDLSLDPQAGYLYWIDCCEYPHIGRVGMDGTNQSVVIETKISRPMALTIDYVNR 3186
Query: 1702 RVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEK 1881
R+YW D + +E + G+ R V +P L LF+ Y+YWTD + + K
Sbjct: 3187 RLYWADE--NHIEFSNMDGSHRHKVPN--QDIPGVIALTLFEDYIYWTDGKTKSLSRAHK 3242
Query: 1882 FGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKD 2061
+L + + + I YH QP + C+ N C +C+L+
Sbjct: 3243 TSGADRLSLIYSWHAI--TDIQVYHSYRQPDVSKHLCM-------INNGGCSHLCLLAP- 3292
Query: 2062 NGGFGVGYKCACP 2100
G + CACP
Sbjct: 3293 ----GKTHTCACP 3301
Score = 233 bits (593), Expect = 1e-58
Identities = 209/844 (24%), Positives = 341/844 (39%), Gaps = 88/844 (10%)
Frame = +1
Query: 4090 VACENDQE-------------TCIPLHQLCDGKTHC------------------------ 4158
V + DQ+ TC+ LCDG C
Sbjct: 23 VGADRDQQLCDPGEFLCHDHVTCVSQSWLCDGDPDCPDDSDESLDTCPEEVEIKCPLNHI 82
Query: 4159 ---------------------PGGTDEGGRCARDLCSADRAGCSFKCHNSPNGPICSCPF 4275
P G DEG C L + + C +KC N C C
Sbjct: 83 ACLGTNKCVHLSQLCNGVLDCPDGYDEGVHCQELLSNCQQLNCQYKCTMVRNSTRCYCED 142
Query: 4276 GEQLVNKTK-CEPENECLDSSSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDT 4452
G ++ + C+ ++EC +CSQ C++ +TCSC EGY + D R+CK D
Sbjct: 143 GFEITEDGRSCKDQDECAVYGTCSQTCRNTHGSYTCSCVEGYLMQPDNRSCKAKIEPTDR 202
Query: 4453 R--IYVSNRNRIYYSDHKLDNWHTFGAIVENAI-ALAWDSLTDRIYWSDIREK------- 4602
+ ++N I T ++ N I L + D I W + RE
Sbjct: 203 PPILLIANFETIEVFYLNGSKMATLSSVNGNEIHTLDFIYNEDMICWIESRESSNQLKCI 262
Query: 4603 KILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLV 4782
+I A T+ I + +A+DW+ RNLY+VD + I V N + L+
Sbjct: 263 QITKAGGLTDEWTINILQSFHNVQQMAIDWLTRNLYFVDHVGDRIFVCN-SNGSVCVTLI 321
Query: 4783 HQNVSQPRGIAVDPRKGVMFWTDWGQNPCIERASMDGTDRQIIVKTKIYWPNTIALDYTT 4962
+ P+ IAVDP G +F+TD+G +ER MDG +R I+ +K P +ALD
Sbjct: 322 DLELHNPKAIAVDPIAGKLFFTDYGNVAKVERCDMDGMNRTRIIDSKTEQPAALALDLVN 381
Query: 4963 DRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYP 5142
VY+ D LD++ V+Y G R V+ + V+H + + +FED +Y ++ +
Sbjct: 382 KLVYWVDLYLDYVGVVDYQGKNRHTVI-QGRQVRHLYGITVFEDYLYATNSDNYNIVRIN 440
Query: 5143 KYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTNP------CSHLCLLNNK-NT 5301
++ NG T + A G+ QP ++++ C +P CSH+CLL++ T
Sbjct: 441 RF-NG-TDIHSLIKIENAWGIRIYQKRTQPTVRSHACEVDPYGMPGGCSHICLLSSSYKT 498
Query: 5302 FTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTN---VFGIEMNSASEKETPVLAGMVPLS 5472
TC+C G L + G+ C + K V G+++N+ E M+P+
Sbjct: 499 RTCRCRTGFNLGSDGRSCKRPKNELFLFYGKGRPGIVRGMDLNTKIADEY-----MIPIE 553
Query: 5473 GLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNGGNKTKMFSSAVPDDA 5652
L N + A + ++ + TT I R ++G + + + D+
Sbjct: 554 NLVNPRALDFHAETNYIYFAD-----------TTSFLIGRQKIDGTERETILKDDL-DNV 601
Query: 5653 YCLGFDWNGRNLVVGNK-ITQTIEIIRTQ-GKQYRSVILSNDQSXXXXXXXXXXXXXXXK 5826
+ DW G NL N +TI + R + Q R +L + S
Sbjct: 602 EGIAVDWIGNNLYWTNDGHRKTINVARLEKASQSRKTLLEGEMS-----HPRGIVVDPVN 656
Query: 5827 GYVFWLDRGGGAADAKVAR---AGLDGSNPLVIASNDLAELDHIAIDTTNTRVYFSEAKA 5997
G+++W D D V R A +DG N + ++ + + + +D +Y+ +A
Sbjct: 657 GWMYWTDWEEDEIDDSVGRIEKAWMDGFNRQIFVTSKMLWPNGLTLDFHTNTLYWCDAYY 716
Query: 5998 GRISSVTYDGQDRHYVLSDGGRQ---PNGLAFYGDRLFYADSAFDSIEVATINGDSQPPQ 6168
I V +G R V S GR+ P GL+ +G+ +F+ D SI D +
Sbjct: 717 DHIEKVFLNGTHRKIVYS--GRELNHPFGLSHHGNYVFWTDYMNGSI----FQLDLITSE 770
Query: 6169 WTHFKKDVENLANIKALQPRASSSGHPCHINNGNCDHICIPLMFAQRTCTCA-NGYVKDG 6345
T + + L ++ PR + C +NNG C +C+ + R C CA N + +
Sbjct: 771 VTLLRHERPPLFGLQIYDPRKQQGDNMCRVNNGGCSTLCLAIP-GGRVCACADNQLLDEN 829
Query: 6346 QTSC 6357
T+C
Sbjct: 830 GTTC 833
Score = 173 bits (439), Expect = 1e-40
Identities = 112/322 (34%), Positives = 146/322 (44%), Gaps = 1/322 (0%)
Frame = +1
Query: 124 ISASVNTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXX-PHPGCKSDQWQCD 300
++A T S C + FRC KCI W P C+ ++QC
Sbjct: 3306 LAADNRTCLSNCTASQFRCKTDKCIPFWWKCDTVDDCGDGSDEPDDCPEFRCQPGRFQCG 3365
Query: 301 TYTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCD 480
T C CD DC D SDE +C T C S F C ++C V+ +C+
Sbjct: 3366 TGL-----CALPAFICDGENDCGDNSDELNC--DTHVCLSGQ-FKCTKNQKCIPVNLRCN 3417
Query: 481 GKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEF 660
G+ DC D DE+D C N +C F+C CI K WVCD DCAD SDE + C+
Sbjct: 3418 GQDDCGDEEDERD-CPEN--SCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEAN-CDK 3473
Query: 661 KKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLK 840
K C +EFQCKN C P +RCD +DC DNSDE+ C C + C G C+
Sbjct: 3474 KTCGPHEFQCKNNNCIPDHWRCDSQNDCSDNSDEENCKPQTCTLKDFLC-ANGDCVSSRF 3532
Query: 841 LCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDIN 1020
CDG DCADG+DE+ C + Q C G+C P+ +K D H C
Sbjct: 3533 WCDGDFDCADGSDERNCETSCSKD---QFRC----SNGQC-IPAKWKCDG--HEDC---- 3578
Query: 1021 ECAEFGYCDQLCANHRPGFTCS 1086
++G ++ C P TCS
Sbjct: 3579 ---KYGEDEKSCEPASP--TCS 3595
Score = 145 bits (367), Expect = 2e-32
Identities = 117/374 (31%), Positives = 159/374 (42%), Gaps = 35/374 (9%)
Frame = +1
Query: 142 TASSVCNE-NDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQ--WQCDTYTW 312
T +S CN ++F C +G+CI + PH KSD+ C+ +
Sbjct: 2505 TKNSSCNAYSEFECGNGECIDYQ------------LTCDGIPHCKDKSDEKLLYCENRSC 2552
Query: 313 -------HSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSK 471
++ CI + CD DC D SDE DC ST C++ F CADG C S
Sbjct: 2553 RRGFKPCYNRRCIPHGKLCDGENDCGDNSDELDCKVST--CATVE-FRCADGT-CIPRSA 2608
Query: 472 KCDGKYDCRDLSDEKDSCSRNHTACFQYQ---------FRCADKTQCIQKSWVCDGSKDC 624
+C+ DC D SDEK+ N+T C + RC + C+ +W+CDGS DC
Sbjct: 2609 RCNQNIDCADASDEKNC---NNTDCTHFYKLGVKTTGFIRCNSTSLCVLPTWICDGSNDC 2665
Query: 625 ADGSDEPDTCEFK---KCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPG 795
D SDE C + KC N F C + RC + CD DC D DE C + C
Sbjct: 2666 GDYSDEL-KCPVQNKHKCEENYFSCPSGRCILNTWICDGQKDCEDGRDEFHC-DSSCSWN 2723
Query: 796 KWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLGCQA---------GCHPSPH 948
++ C CI + +CDG DC DG DE S ++C ++ C A C P
Sbjct: 2724 QFAC-SAQKCISKHWICDGEDDCGDGLDE---SDSICGAITCAADMFSCQGSRACVPRHW 2779
Query: 949 --GGECTCPSGYKLDDRFHRTCSDINECAEFGYC--DQLCANHRPGFTCSCLGDCFTLQM 1116
GE CP G D+ C+ N C E + +++C + F C DC
Sbjct: 2780 LCDGERDCPDG--SDELSTAGCAPNNTCDENAFMCHNKVCIPKQ--FVCDHDDDC----- 2830
Query: 1117 EHGPGKDNLTMRGY 1158
G G D GY
Sbjct: 2831 --GDGSDESPQCGY 2842
Score = 142 bits (358), Expect = 2e-31
Identities = 94/283 (33%), Positives = 128/283 (45%), Gaps = 7/283 (2%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQ 453
CK+ +++C CI +CD DC DGSDE C F C + R
Sbjct: 845 CKAGEFRCKNR-----HCIQARWKCDGDDDCLDGSDEDSVNCFNHSCPDDQ-FKCQNNR- 897
Query: 454 CFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADG 633
C CDG DC DE + T C QF C + +CI ++W+CD DC D
Sbjct: 898 CIPKRWLCDGANDCGSNEDESNQTCTART-CQVDQFSCGN-GRCIPRAWLCDREDDCGDQ 955
Query: 634 SDEPDTCEFKKC-TANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCP 810
+DE +CEF C +F CK+ RC K+ CD DDCGD SDE C + C ++ C
Sbjct: 956 TDEMASCEFPTCEPLTQFVCKSGRCISSKWHCDSDDDCGDGSDEVGC-VHSCFDNQFRC- 1013
Query: 811 GTGHCIDQLKLCDGSKDCADGADEQQCS---QNLCPSLGCQAG---CHPSPHGGECTCPS 972
+G CI CDG DC D +DE Q + + + GC CHP G C P
Sbjct: 1014 SSGRCIPGHWACDGDNDCGDFSDEAQINCTKEEIHSPAGCNGNEFQCHPD---GNCV-PD 1069
Query: 973 GYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDC 1101
++ D + C D ++ +LC +H+ F+C G C
Sbjct: 1070 LWRCDG--EKDCEDGSDEKGCNGTIRLC-DHKTKFSCWSTGRC 1109
Score = 128 bits (322), Expect = 4e-27
Identities = 80/228 (35%), Positives = 102/228 (44%), Gaps = 3/228 (1%)
Frame = +1
Query: 430 FMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCD 609
F C + R C KCDG DC D SDE NH+ C QF+C + +CI K W+CD
Sbjct: 850 FRCKN-RHCIQARWKCDGDDDCLDGSDEDSVNCFNHS-CPDDQFKCQNN-RCIPKRWLCD 906
Query: 610 GSKDCADGSDEPD-TCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEY-R 783
G+ DC DE + TC + C ++F C N RC PR + CD DDCGD +DE E+
Sbjct: 907 GANDCGSNEDESNQTCTARTCQVDQFSCGNGRCIPRAWLCDREDDCGDQTDEMASCEFPT 966
Query: 784 CPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECT 963
C P +G CI CD DC DG+DE GC S +
Sbjct: 967 CEPLTQFVCKSGRCISSKWHCDSDDDCGDGSDE--------------VGCVHSCFDNQFR 1012
Query: 964 CPSGYKLDDRFHRTCSDINECAEFGYCDQL-CANHRPGFTCSCLGDCF 1104
C SG + H C N+C +F Q+ C C G+ F
Sbjct: 1013 CSSGRCIPG--HWACDGDNDCGDFSDEAQINCTKEEIHSPAGCNGNEF 1058
Score = 92.4 bits (228), Expect = 3e-16
Identities = 52/149 (34%), Positives = 74/149 (48%), Gaps = 6/149 (4%)
Frame = +1
Query: 478 DGKYDCRDLSD----EKDSCSRNHTACFQY-QFRCADKTQCIQKSWVCDGSKDCADGSDE 642
+G+ +C D E + C +++C Y +F C + +CI CDG C D SDE
Sbjct: 2484 NGRVNCSCRGDRILLEDNRCVTKNSSCNAYSEFECGNG-ECIDYQLTCDGIPHCKDKSDE 2542
Query: 643 PDT-CEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTG 819
CE + C C N+RC P CD +DCGDNSDE +C C ++ C G
Sbjct: 2543 KLLYCENRSCRRGFKPCYNRRCIPHGKLCDGENDCGDNSDELDCKVSTCATVEFRC-ADG 2601
Query: 820 HCIDQLKLCDGSKDCADGADEQQCSQNLC 906
CI + C+ + DCAD +DE+ C+ C
Sbjct: 2602 TCIPRSARCNQNIDCADASDEKNCNNTDC 2630
Score = 75.5 bits (184), Expect = 4e-11
Identities = 110/476 (23%), Positives = 184/476 (38%), Gaps = 63/476 (13%)
Frame = +1
Query: 7579 EIRHISDMKLDWLTQKIYFT-----------TGRGGKVMAIDTAGE-------HLSTIAS 7704
E + D+ +DW+ IY+T T + G+ L T +
Sbjct: 3967 EFKRPRDIAVDWVAGNIYWTDHSRMHWFSYYTTHWTSLRYSINVGQLNGPNCTRLLTNMA 4026
Query: 7705 GDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAV 7884
G+ YA+A++P G+++W+ G + IE + + G R+++V +++ P +AV
Sbjct: 4027 GE-PYAIAVNPKRGMMYWTVVGDHS-------HIEEAAMDGTLRRILVQKNLQRPTGLAV 4078
Query: 7885 DFRNQKIYWADVNRLNIEVADYDGQNRKVIASGYRA----KSLDIWDRWLYMSDPLSNGV 8052
D+ +++IYWAD I YDG N V S + +DI++ ++Y + P NGV
Sbjct: 4079 DYFSERIYWADFELSIIGSVLYDGSNSVVSVSSKQGLLHPHRIDIFEDYIYGAGP-KNGV 4137
Query: 8053 FRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLCT 8232
FR+ K +E + + + + + N + LC + G +C
Sbjct: 4138 FRVQKFGHGSVEYLALNIDKTKGVLISHRYKQLDLPNPCLDLACEFLCLLNPSGATCVCP 4197
Query: 8233 VVADDIGLAASKVQCSCNDTYELVQEPGK---DYPTQCVLRGSNSEPAKECLPPY----- 8388
+ +CND L+ + K + +C+L + C P Y
Sbjct: 4198 E-------GKYLINGTCNDD-SLLDDSCKLTCENGGRCIL-NEKGDLRCHCWPSYSGERC 4248
Query: 8389 ------NFQCGDGSCI--LLG-ATCD-----SKPDCADASDE----NPNYCNTRSCPEDY 8514
N+ G+C+ +LG TC + P+C E N C + + Y
Sbjct: 4249 EVNHCSNYCQNGGTCVPSVLGRPTCSCALGFTGPNCGKTVCEDFCQNGGTCIVTAGNQPY 4308
Query: 8515 NLC----TNRRCIDSAKKCNHI----DDC---GDGSDELDCPS---AVAC-AEGTFPCSN 8649
C T RC C+H + C DGS E CP+ C + C
Sbjct: 4309 CHCQPEYTGDRC--QYYVCHHYCVNSESCTIGDDGSXECVCPTRYEGPKCEVDKCVRCHG 4366
Query: 8650 GHCINQTKVCDGHNDCHDEQVSDESLATCPGLPIDCRGVKVRCPNTNICIQPADLC 8817
GHCI D +C + +++ S C G + G P TN+ P LC
Sbjct: 4367 GHCIINKDSEDIFCNCTNGKIA-SSCQLCDGYCYN-GGTCQLDPETNV---PVCLC 4417
Score = 66.2 bits (160), Expect = 2e-08
Identities = 82/333 (24%), Positives = 138/333 (40%), Gaps = 17/333 (5%)
Frame = +1
Query: 2404 MSFDWISKQLYYVDNIR-----------NSLEV-VKIGETGLVHPDELVRRQLITELRDP 2547
++ DW++ +Y+ D+ R SL + +G+ L P+ R L +P
Sbjct: 3974 IAVDWVAGNIYWTDHSRMHWFSYYTTHWTSLRYSINVGQ--LNGPN--CTRLLTNMAGEP 4029
Query: 2548 VSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGD 2727
++ V+P +G++++ + I +DG +++ L RP+ +A+D+ R+ W D
Sbjct: 4030 YAIAVNPKRGMMYWTVVGDHSHIEEAAMDGTLRRILVQKNLQRPTGLAVDYFSERIYWAD 4089
Query: 2728 TLLKTISCMDFDGKN-VVKLDIDNPI--PVAITIMNEYIYYVHQRPYSIRRVHKKNGGGS 2898
L I + +DG N VV + + P I I +YIY + + RV +K G GS
Sbjct: 4090 FELSIIGSVLYDGSNSVVSVSSKQGLLHPHRIDIFEDYIYGAGPK-NGVFRV-QKFGHGS 4147
Query: 2899 KIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKC 3078
D+ + SH+ + + +PC C LC PS A C
Sbjct: 4148 VEYLALNIDKTKGVLI---SHRYKQL---DLPNPCLDLACEFLCLLNPS-------GATC 4194
Query: 3079 ACRQG-FMINKENNHSCQKDPAEKIEQLCSSNSTQFQCKN-GRCIPKEWKCDGENDCLDE 3252
C +G ++IN N D +S + C+N GRCI E K D C
Sbjct: 4195 VCPEGKYLINGTCNDDSLLD-----------DSCKLTCENGGRCILNE-KGDLRCHCWP- 4241
Query: 3253 SDEIDEKGDKCFHETECAENTIKCRNTKKCIPA 3351
G++C E + C+N C+P+
Sbjct: 4242 ----SYSGERC----EVNHCSNYCQNGGTCVPS 4266
Score = 65.1 bits (157), Expect = 5e-08
Identities = 65/257 (25%), Positives = 107/257 (41%), Gaps = 22/257 (8%)
Frame = +1
Query: 12967 KKIVAGHLQQPTALITAPSAGRICYSD------AGLHAKIECADMDGTHRQIIVKDLVFS 13128
K ++ G + P ++ P G + ++D +IE A MDG +RQI V +
Sbjct: 637 KTLLEGEMSHPRGIVVDPVNGWMYWTDWEEDEIDDSVGRIEKAWMDGFNRQIFVTSKMLW 696
Query: 13129 PTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHI--PYAVDVFENHIYWLS 13302
P + +D N +YW D Y ++ V ++G+ R V R + P+ + N+++W
Sbjct: 697 PNGLTLD-FHTNTLYWCDAYYDHIEKVFLNGTHRKIVYSGRELNHPFGLSHHGNYVFWTD 755
Query: 13303 RESKTLYVQDKFGRGRVSVLASDLED--GHTVRVSQKYAKDTQRTVSGCERAQCSHLCVS 13476
+ +++ D V++L + G + +K D V+ CS LC++
Sbjct: 756 YMNGSIFQLDLI-TSEVTLLRHERPPLFGLQIYDPRKQQGDNMCRVN---NGGCSTLCLA 811
Query: 13477 LPSTGFACLCPDGIVPQLDG-SCATQHVEALTMPKQCK-----CTN------GGKCRLDG 13620
+P G C C D + +G +C EAL P CK C N KC D
Sbjct: 812 IPG-GRVCACADNQLLDENGTTCTFNPGEAL--PHICKAGEFRCKNRHCIQARWKCDGDD 868
Query: 13621 SCECTSDFEGDQCEKES 13671
C SD + C S
Sbjct: 869 DCLDGSDEDSVNCFNHS 885
Score = 56.6 bits (135), Expect = 2e-05
Identities = 44/153 (28%), Positives = 62/153 (39%), Gaps = 11/153 (7%)
Frame = +1
Query: 271 GCKSDQWQCDT--YTWHS-VSCIAEYQRCDNITDCADGSDEK--DCPASTVDCSSQNVFM 435
G DQ CD + H V+C+++ CD DC D SDE CP N
Sbjct: 24 GADRDQQLCDPGEFLCHDHVTCVSQSWLCDGDPDCPDDSDESLDTCPEEVEIKCPLNHIA 83
Query: 436 CADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVC--- 606
C +C +S+ C+G DC D DE C + C Q C K ++ S C
Sbjct: 84 CLGTNKCVHLSQLCNGVLDCPDGYDEGVHCQELLSNC--QQLNCQYKCTMVRNSTRCYCE 141
Query: 607 DGSKDCADG---SDEPDTCEFKKCTANEFQCKN 696
DG + DG D+ + + C+ C+N
Sbjct: 142 DGFEITEDGRSCKDQDECAVYGTCSQT---CRN 171
Score = 38.5 bits (88), Expect = 4.9
Identities = 29/111 (26%), Positives = 45/111 (40%), Gaps = 7/111 (6%)
Frame = +1
Query: 13375 EDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTGFACLCPDGIVPQLDGSCATQH 13554
+DG V + + V C R H ++ S C C +G ++ SC
Sbjct: 4339 DDGSXECVCPTRYEGPKCEVDKCVRCHGGHCIINKDSEDIFCNCTNG---KIASSC---- 4391
Query: 13555 VEALTMPKQCK--CTNGGKCRLDGS-----CECTSDFEGDQCEKESSVSRK 13686
+ C C NGG C+LD C C++++ G QCE+ + S K
Sbjct: 4392 -------QLCDGYCYNGGTCQLDPETNVPVCLCSTNWSGTQCERPAPKSSK 4435
>gi|16519539|ref|NP_443737.1| low density lipoprotein-related protein
1B; low density lipoprotein receptor related protein
LRP1B/LRP-DIT [Mus musculus]
gi|46577126|sp|Q9JI18|LR1B_MOUSE Low-density lipoprotein
receptor-related protein 1B precursor (Low-density
lipoprotein receptor-related protein-deleted in tumor)
(LRP-DIT)
gi|8926243|gb|AAF81758.1| low density lipoprotein receptor related
protein LRP1B/LRP-DIT [Mus musculus]
Length = 4599
Score = 1877 bits (4863), Expect = 0.0
Identities = 1342/4530 (29%), Positives = 2059/4530 (44%), Gaps = 198/4530 (4%)
Frame = +1
Query: 667 CTANEFQCKNK-RCQPRKFRCDYYDDCGDNSDE--DECGE---YRCPPGKWNCPGTGHCI 828
C EF C + C + + CD DC D SDE D C E +CP C G+ C+
Sbjct: 32 CDPGEFLCHDHVTCVSQSWLCDGDPDCPDQSDESLDTCPEEVEIKCPLNHIACHGSSACV 91
Query: 829 DQLKLCDGSKDCADGADEQQCSQNLCPS---LGCQAGCHPSPHGGECTCPSGYKLDDRFH 999
KLC+G DC DG DE Q L PS L CQ C + C C G+++ +
Sbjct: 92 HLSKLCNGVVDCPDGFDEGGHCQELLPSCQQLNCQFKCAMVRNATRCYCEDGFEVAED-G 150
Query: 1000 RTCSDINECAEFGYCDQLCANHRPGFTCSCL------GDCFTLQMEHGPGKDNLTMRGYC 1161
R+C D +EC+ +G C Q C N + CSC+ D + +++H P D M
Sbjct: 151 RSCKDQDECSIYGICSQTCKNTYGSYACSCVEGYIMQSDNRSCKVKHEP-TDKAPM---L 206
Query: 1162 VSNNADKMKLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHS 1341
+ ++ + ++LF + L+ N +E I+ +DF Y + I W + S
Sbjct: 207 LISSLETIELFYINGSKMTTLSSANRNE----------IHTLDFIYSEEMICWIE----S 252
Query: 1342 AFSADVDDEGEISQIKKL-------SLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSY 1500
S++ G+I++ +L SL+S +A DW+T +Y ++ S RI V ++
Sbjct: 253 RESSNQLKCGQITKAGRLTDQRIINSLQSFQNVEQMAFDWLTRNIYFVDHVSDRIFVCNF 312
Query: 1501 DGERRTVLLADGLTLPLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQV 1671
+G L+ L P IA DP+ G++FFT N K+E +DG NR +V + Q
Sbjct: 313 NGSVCVTLIESELHNPKAIAADPIAGKLFFTDYGNVPKIERCDLDGMNRTRIVYSKAEQP 372
Query: 1672 SGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDW 1851
S + +D+ + VYWVD +D + +DYQG +R + QG V H +G+ +F+ YLY T
Sbjct: 373 SALALDLVNRLVYWVDLYLDYVGVVDYQGKNRHTIVQGRQV-KHLYGITVFEDYLYATSS 431
Query: 1852 TRLGVIQVEKF-GSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNA 2028
+I++ +F G+D + GI Y QP C P
Sbjct: 432 DNFNIIRINRFNGTDIHSIIKMESAR----GIRTYQKRTQPTVRSHACEVDAYGMP---G 484
Query: 2029 DCEGMCILSKDNGGFGVGYK---CACPIGQKL-VNGKRCIDSIDYLLFSSNK----IVRG 2184
C +C+LS YK C C G + +G+ C + L K IVRG
Sbjct: 485 GCSHICLLSSS-------YKTRTCRCRTGFNMGSDGRSCKRPKNELFLFYGKGRPGIVRG 537
Query: 2185 IFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGA 2364
+ ++N K E ++PI + R ++ N ++AD I R + DG
Sbjct: 538 M--DLNTKIADECMIPIENLVNPRA-----LDFHAEANYIYFADTTSFLIGRQKIDGTER 590
Query: 2365 APVLVTHNDGLFSMSFDWISKQLYYV-DNIRNSLEVVKIGETGLVHPDELVRRQLITE-- 2535
+L D + ++ DWI LY+ D R ++ V ++ + R+ + E
Sbjct: 591 ETILKDDLDNVEGIAVDWIGNNLYWTNDGHRKTINVARLEKASQ-------SRKTLLEGG 643
Query: 2536 LRDPVSVVVHPWKGLLFYAEAMRP------AAIYRCHIDGQNCQVIRNTTLGRPSEMAID 2697
+ P ++VV P G +++ + I + +DG N QV + + P+ + +D
Sbjct: 644 MSHPRAIVVDPVNGWMYWTDWKEDKIDDSVGRIEKAWMDGVNRQVFVTSKMLWPNGLTLD 703
Query: 2698 FAENRLCWGDTLLKTISCMDFDG--KNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRR 2871
F + L W D I + +G + VV + P ++ Y+++ SI +
Sbjct: 704 FHTSTLYWCDAYYDHIEKVFLNGTHRKVVYSGKELNHPFGLSHHGNYVFWTDYMNGSIFQ 763
Query: 2872 VHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQ--CTQLCFATPS 3045
+ + + E +F L+ + Q ++ CR + C LC A P+
Sbjct: 764 LDLMTNEVTLLRHE----RAPLFGLQIYDPRKQ-----QGDNMCRINNGGCGTLCLAIPA 814
Query: 3046 ESHPNELEAKCACRQGFMINKENNHSCQKDPAEKIEQLCSSNSTQFQCKNGRCIPKEWKC 3225
CAC +++ EN +C +P E +C +F+CKN CI WKC
Sbjct: 815 GR-------VCACADNQLLD-ENGTTCTFNPEEIRFHICKPG--EFRCKNKHCIQARWKC 864
Query: 3226 DGENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXV 3405
DG++DCLD SD E+++ C N
Sbjct: 865 DGDDDCLDGSD----------------EDSVTCFNHS----------------------- 885
Query: 3406 KYCKDGQKPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNATCAANQFSCA 3585
C D Q F+C N+RCIP++W E + C TC A+QFSC
Sbjct: 886 --CPDDQ--------FKCQNNRCIPKRWLCDGANDCGSNEDESNQTCTARTCQADQFSCG 935
Query: 3586 NGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSAL-QFRCANGRQCVPLRNHXXXXXXX 3762
NGRCIP WLCD ++DC D TDE C C L QF C +GR C+ + H
Sbjct: 936 NGRCIPTAWLCDREDDCGDQTDEVAS-CEFPTCEPLTQFICKSGR-CISNKWHCDTDDDC 993
Query: 3763 XXXXXXXXXAVTAESCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCT-----S 3927
SC DQF+C SSG CIP W SDE CT S
Sbjct: 994 GDRSDEVG---CVHSCLDDQFRC-SSGRCIPGHWACDGDNDCGDFSDETHINCTKEEARS 1049
Query: 3928 GRQCSSDQFKCG-NGRCILNNWLCDGENDCGDGSDESSERGC------KTSMNARK---- 4074
C ++F+C +G CI + W CDGE DC DGSDE G KT + R
Sbjct: 1050 PAGCIGNEFQCRPDGNCIPDLWRCDGEKDCEDGSDEKGCNGTIRLCDHKTKFSCRSTGRC 1109
Query: 4075 --------------------------CPFEHVACENDQETCIPLHQLCDGKTHCPGGTDE 4176
C C ND C+ +LC+G+ CP G+DE
Sbjct: 1110 INNAWVCDGDVDCEDQSDEEDCDSFLCGPPKYPCANDTSVCLQPEKLCNGRKDCPDGSDE 1169
Query: 4177 GGRCARDLCSADRAGCSFKCHNSPN-GPICSCPFGEQLVNKTK-CEPENECLDSSSCSQR 4350
G C D CS + GCS C P G +CSCP G QL + CE + C CSQ
Sbjct: 1170 GDLC--DECSLNNGGCSNHCSVVPGRGIVCSCPEGHQLKKDNRTCEIVDYCASHLRCSQV 1227
Query: 4351 CKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGAI 4530
C+ +KH CSC EG+ L D +C D+ + I+ S R+ I D ++
Sbjct: 1228 CEQQKHMVKCSCYEGWALGTDGESCTSVDSFEAFIIF-SIRHEIRRIDLHKGDYSLLVPG 1286
Query: 4531 VENAIALAWDSLTDRIYWSDIREKKI----LSANRNGTNATVFIADGLDITEGIALDWVG 4698
+ N IAL + +YW+D+ E +I LS + + V + GL EG+ +DW+
Sbjct: 1287 LRNTIALDFHFNQSLLYWTDVVEDRIYRGKLSESGGVSAIEVVVEHGLATPEGLTVDWIA 1346
Query: 4699 RNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQN-PCIE 4875
N+YW+DS+L+ IEV+ L D R L+ + PR IA+DPR G++FWTDW N P IE
Sbjct: 1347 GNIYWIDSNLDQIEVSKL-DGSLRATLIAGAMEHPRAIALDPRYGILFWTDWDANFPRIE 1405
Query: 4876 RASMDGTDRQIIVKTKIY--WPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLAS 5049
ASM G R+ I K WPN + +D+ R+ + D++ D I YDG+ +++
Sbjct: 1406 SASMSGAGRKTIYKDMKTGAWPNGLTVDHFERRIVWTDARSDAIYSAFYDGTNMIEIIRG 1465
Query: 5050 SKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQ 5229
+++ HP A++++ +Y++D R L K+ G T ++ + HP Q
Sbjct: 1466 HEYLSHPFAVSLYGSEVYWTDWRTNTLAKANKW-TGQNVSVIQKTSAQPFDLQIYHPSRQ 1524
Query: 5230 PVIKNNPCSTN----PCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKPFLVIIQKT 5397
P N PC+ N PCSHLCL+N+ + C CP KL + K C + K FL+ +++
Sbjct: 1525 PQAPN-PCAANEGRGPCSHLCLINHNRSAACACPHLMKLSSDKKTCYE-MKKFLLYARRS 1582
Query: 5398 NVFGIEMNSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTD 5577
+ G+++++ + A VP + + +DA E ++ + I T
Sbjct: 1583 EIRGVDIDNPYVNF--ITAFTVP--DIDDVAVIDFDASEERLYWTD----------IKTQ 1628
Query: 5578 SAIYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLV-VGNKITQT-IEIIRTQGKQYR 5751
+ I R+ +NG + S + L DW RNL + ++ +T I + R G
Sbjct: 1629 T-ITRAFINGTGLETVISRDI-QSIRGLAVDWVSRNLYWISSEFDETQINVARLDGSLKT 1686
Query: 5752 SVILSNDQSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDL 5931
S+I D+ +G ++W D + A +DGSN ++ N
Sbjct: 1687 SIIHGIDKPQCLAAHPV-------RGKLYWTDGN------TINMANMDGSNSKILFQNQK 1733
Query: 5932 AELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYV--LSDGGRQPNGLAFYGDRLFY 6105
+ ++ID ++Y+ + G I+ DG + + + + + L +L++
Sbjct: 1734 EPVG-LSIDYVENKLYWISSGNGTINRCNLDGGNLEVIESMKEELTKATALTIMDKKLWW 1792
Query: 6106 ADSAFDSIEVATINGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHINNGNCDHIC 6285
AD + P + + + ++K A + C +NNG C +C
Sbjct: 1793 ADQNLAQLGTCNKRDGRNP---SILRNKTSGVVHMKVYDKEAQQGSNSCQVNNGGCSQLC 1849
Query: 6286 IPLMFAQRTCTCANGY-VKDGQTSCKLFDESFVIVATKTKVIGYPIDETQSKGVAMEPIG 6462
+P RTC C GY ++ + SC+ ESF++ + + G P+ E + K A+ PI
Sbjct: 1850 LPTSETTRTCMCTVGYYLQKNRMSCQGI-ESFLMYSVHEGIRGIPL-EPRDKVDALMPIS 1907
Query: 6463 GLSIT-GVDYDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWI 6639
G + G+D+ E+ TIY + G+NK I+ ++ V+ + +G ++ +A+DWI
Sbjct: 1908 GAAFAVGIDFHAENDTIYWTDM-GLNK-ISRAKRDQTWKEDVVTNGLGR--VEGIAVDWI 1963
Query: 6640 NYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTI 6819
N+Y+ +H IEV++L+G++R ++++ + P SIAV P +L+W + GQ P I
Sbjct: 1964 AGNIYWTDHGFNL--IEVARLNGSFRYVIISQGLDQPRSIAVHPEKGFLFWTEWGQVPCI 2021
Query: 6820 QRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVR-STGGTPELVRSD 6996
++ LDGS + +IVS GI P + +D +YW DA+ D I R+ TG E++ S
Sbjct: 2022 GKARLDGSEKVMIVSVGITWPNGISIDYEENKLYWCDARSDKIERIDLDTGANREVLLSG 2081
Query: 6997 I-ASAAGVALHGQNMYWTDN-RLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSS 7170
VA+ G +YW+D R K + T + T + +LK+I +F+
Sbjct: 2082 SNVDLFSVAVFGAYIYWSDRAHANGSVRRGHKNDATETVTMRTGLGVNLKEI---KIFNR 2138
Query: 7171 NNQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCARGVLKGR--TCEEPDTYIMFS 7344
+ + ++ C C QLC G TC+CA G L G TC + Y+++S
Sbjct: 2139 VRE-KGTNVCA----KENGGCQQLCLYR-GNSRRTCACAHGYLAGDGVTCLRHEGYLLYS 2192
Query: 7345 DGDKIIDVAIEPDVKASRPLKDPFPE---ISNLQTFDVDVNLRRVYFVVESPVGVNISWF 7515
+ + + + + P++ P+ N+ D N RR G N ++
Sbjct: 2193 GRTILKSIHLSDETNLNSPVR-PYENPNYFKNIIALAFDYNQRRE--------GTNRIFY 2243
Query: 7516 SMNNAENPRLVFG--ASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVM--------- 7662
S + N +L+ +Q + + + + +Y+T+ +
Sbjct: 2244 SDAHFGNIQLIKDNWEDRQVIVENVGSVEGLAYHRAWDTLYWTSSSTSSITRHTVDQTRP 2303
Query: 7663 -AIDTAGEHLSTIASGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRK 7839
AID E + T++ D + LA+D C L+FW T+ P I R+ L G +
Sbjct: 2304 GAIDR--EAVITMSEDDHPHVLALDECQNLMFW------TNWNEQHPSIMRATLTGKNAH 2355
Query: 7840 VIVSESISLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGYRAK--SLDIWD 8013
V+VS I P + +D R +K+Y++D + IE +YDG R VI SL ++D
Sbjct: 2356 VVVSTDILTPNGLTIDHRAEKLYFSDGSLGKIERCEYDGSQRHVIVKSGPGTFLSLAVYD 2415
Query: 8014 RWLYMSDPLSNGVFRIDKESGSGLENVVSDRRIPGA-LRVFASESDVRTRNQVCNALTSQ 8190
+++ SD + R +K +G + + SD IP + + A +D N+
Sbjct: 2416 SYIFWSDWGRRAILRSNKYTGGETKILRSD--IPHQPMGIIAVANDT-------NSCELS 2466
Query: 8191 LCKTDNGGCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSEPAK 8370
C NGGC LC + D +V CSC L+ +CV + S+
Sbjct: 2467 PCALLNGGCHDLCLLTPD------GRVNCSCRGDRVLLAN------NRCVTKNSSCNIYS 2514
Query: 8371 ECLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSA 8550
E F+CG+G C+ TCD P C D SDE YC RSC + C NRRC+
Sbjct: 2515 E------FECGNGDCVDYVLTCDGIPHCKDKSDEKLLYCENRSCRSGFKPCYNRRCVPHG 2568
Query: 8551 KKCNHIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLA 8730
K C+ +DCGD SDELDC + C+ F C++G CI ++ C+ + DC D SDE
Sbjct: 2569 KLCDGTNDCGDSSDELDCKVST-CSTVEFRCADGTCIPRSARCNQNMDCSD--ASDEKGC 2625
Query: 8731 TCPGLPIDCR-----GVK----VRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQ-Q 8880
DC GVK +RC +T++C+ P+ +CDG +DCGD +DE + N+ +
Sbjct: 2626 N----NTDCTHFYKLGVKSTGFIRCNSTSLCVLPSWICDGSNDCGDYSDELKCPVQNKHK 2681
Query: 8881 CAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCI 9060
C ++Y CPSGRCI TW CDG DC DG DE H + + + + F C KCI
Sbjct: 2682 CEENYFGCPSGRCILNTWVCDGQKDCEDGLDELHCDSSCSWNQ--------FACSVKKCI 2733
Query: 9061 SRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDV 9240
S+ +I S CG TC F C Q + C+P+ WLCDG+
Sbjct: 2734 SKHWICDGEDDCGDSLD-ESDSICGAVTCAADMFSC-------QGSHACVPQHWLCDGER 2785
Query: 9241 TCAGGEDESTELCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSC 9420
C G DE + C++ F C N+ CI + CD D+DC DGSDE C Y C
Sbjct: 2786 DCPDGSDELSSAGCAPNNTCDENAFMCHNKVCIPKQFVCDHDDDCGDGSDEFLQCGYRQC 2845
Query: 9421 QPDFFQCANHKCVPNS-WKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTSGEC 9597
P+ F+CA+ +C+ N+ W+CDG+ DC D SDE P N C++ F C +G C
Sbjct: 2846 GPEEFRCADGRCLVNTLWQCDGDFDCPDSSDE--APINPRCRSAEHSCNSSFFMCKNGRC 2903
Query: 9598 IDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDIS 9777
I +CD DC D SDE++ C I+EC + C Q C D+ + YKC C+ GF +
Sbjct: 2904 IPSDGLCDIRDDCGDGSDETN-CHINECLSKKISGCSQDCQDLPVSYKCKCWPGFQLK-D 2961
Query: 9778 DQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLA 9957
D K+C +++EC G CSQ+C + G+YKC C +GY+ D+ + R+ + EPF +LA
Sbjct: 2962 DGKTCVDIDECSSGFP-CSQQCINTYGTYKCHCAEGYETQPDNPNGCRSLSDEEPFLILA 3020
Query: 9958 NKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLS 10137
++H IRKIS DG+ Y L QG +NV++LD D E+ Y ID + R++ L+
Sbjct: 3021 DQHEIRKISTDGSNYTLLKQGLNNVIALDFDYREEFIYWIDSSRPNGSRIN----RMCLN 3076
Query: 10138 SYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIV 10317
+ + HN +AVDW+G+ LY + ++R I V +L+G + L+ R++ P+ +
Sbjct: 3077 GSDIKVVHNTAVPNALAVDWIGKNLYWSDTEKRIIEVSKLNGLYPTVLVSKRLKFPRDLS 3136
Query: 10318 VHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWG 10497
+ P G L++ + P+IGR+ +DG+ + + E + P A+ IDY + RL+W
Sbjct: 3137 LDPRAGNLYWIDCCEYPHIGRVGMDGTNQ-----SVVIETKISRPMALTIDYVNHRLYWA 3191
Query: 10498 DAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNET 10677
D N I F + DG+ R +P Q V ++ +F+DY+YW D + + R K +G +
Sbjct: 3192 DE--NHIEFSNMDGSHRHKVPNQDIPGVIALTLFEDYIYWTDGKTKSLSRVHKTSGADRL 3249
Query: 10678 ILKKTVQLPNDLRIVHPMRQP-AYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLS 10854
L + D+++ H RQP + C NNGGCSHLCL+G G +TC+CP F L +
Sbjct: 3250 SLINSWHAITDIQVYHSYRQPDVSKHLCTVNNGGCSHLCLLGP-GKTHTCACPTNFYLAA 3308
Query: 10855 DQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQC 11034
D +TC NCT QF C D KCIP W CD DC DGSDEP + C + C G FQC
Sbjct: 3309 DNRTCLSNCTASQFRCKTD--KCIPFWWKCDTVDDCGDGSDEPDD--CPEFKCQPGRFQC 3364
Query: 11035 TNHNCTRPFQIXXXXXXXXXXXXEQNCD-KACDPWMFKCAATGRCIPRRFTXXXXXXXXX 11211
C P I E NCD C FKC +CIP
Sbjct: 3365 GTGLCALPAFICDGENDCGDNSDELNCDTHVCLAGQFKCTKNKKCIPVNLRCNGQDDCGD 3424
Query: 11212 RSDEADTLCMSAERNCTAEEFRCNNNK-CIAKAWRXXXXXXXXXXXXETPECAQIECKKG 11388
DE D E +C+ + F+C K CI+K W E C + C
Sbjct: 3425 EEDEKD----CPENSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEA-NCDKKTCGPH 3479
Query: 11389 WTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMCDT 11568
+C ++ CIP+ C+ Q+DC DNSDED + TC + +F C ++G C+ R+ CD
Sbjct: 3480 EFQCKNN-NCIPDHWRCDNQNDCSDNSDEDNCKPQTC-TLKDFLC-SNGDCVSSRFWCDG 3536
Query: 11569 ENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQC--TL 11742
E DC D SDE + CS+ +F+C++G+C+ CDG C G DE C
Sbjct: 3537 EFDCADGSDEKNCETS-----CSKDQFQCSNGQCLSAKWKCDGHEDCKYGEDEKNCEPAF 3591
Query: 11743 RRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHC----------------------- 11853
C C G C++ C+ + DC + +DE+ C
Sbjct: 3592 PVCSSSEYMCASGGCLSASLKCNGEPDCVDGSDEMDCVIECKEDQFQCKNKAYCIPIRWL 3651
Query: 11854 ------------EDVSRR---TCSPFEFECANSVCIPRKFMXXXXXXXXXXSDETSSECR 11988
E+ R C EF C NS+C ++ SDE C
Sbjct: 3652 CDGIYDCVDGSDEETCGRGGSICRDDEFLCNNSLCKLHFWVCDGEDDCGDNSDEAPDMCV 3711
Query: 11989 SAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSFSEYGDCSSDQFKC 12168
C P +RC + R+CL + ++CNG NDCG N +EH S S C D+F C
Sbjct: 3712 KFLCPPTRPYRCRNDRICLQLEKICNGINDCGDNS-DEEHCSGKLSLKS-KPCKKDEFTC 3769
Query: 12169 ANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKHICTDVRDGFYCHC 12348
+N C+ + CD DDCGD SDE GC K + +CE GN G C ++ +C C
Sbjct: 3770 SNRNCIPMELQCDSLDDCGDGSDEQGCLKTPIEHTCENNGNPCGDDAYCNQIKTSVFCRC 3829
Query: 12349 RDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCR 12528
+ GF+ + + +EC D++EC C+ CLNT+GSY C C ++++ C
Sbjct: 3830 KPGFQRNMKG-RECADLNECLLFGICSHHCLNTRGSYKCVCDQNFQEK-------NNSCI 3881
Query: 12529 AKGDAANVM-IGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWID-- 12699
AKG + I D ++ + + H ++ ++ W
Sbjct: 3882 AKGSEDQALYIANDTDILGFVYPFNYSGGHQQISHVEHNSRITGMDVHYQRNVIVWSTQF 3941
Query: 12700 GSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAVSENIENGLV 12879
Y+ A + + +F P IAVD+ GN++ S
Sbjct: 3942 NPGGIFYKMIDAREKRQANSGLICPEFKR----PRDIAVDWVAGNVYWTDHSRMHWFSYY 3997
Query: 12880 TARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLH 13059
T + I N G + +G +++ +P A+ P G + ++ G H
Sbjct: 3998 TTHWTSLRYSI---NVGQL-----NGPNCTRLLTNMAGEPYAIAVNPKRGMMYWTVIGDH 4049
Query: 13060 AKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTV 13239
+ IE A MDGT R+++V+ + PT + +D G RIYW D + + +V DGS
Sbjct: 4050 SHIEEAAMDGTLRRVLVQKNLQRPTGLTVDH-FGERIYWADFELSIIGSVLYDGSSPVVS 4108
Query: 13240 VHDRH---IPYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKY 13410
V + P+ +DVFE++IY ++ VQ KFG G V VLA ++ ++ VS +Y
Sbjct: 4109 VSSKQGLLHPHRIDVFEDYIYGAGPKNGIFRVQ-KFGHGSVEVLALGVDKTKSILVSHRY 4167
Query: 13411 AKDTQRTVSGCERAQCSHLCVSLPSTGFACLCPDGIVPQLDGSCATQHVEALTMPKQCK- 13587
+ + C C LC+ PS G C+CP+G ++G+C H ++L + CK
Sbjct: 4168 KQ--LNLPNPCLDLSCDFLCLLNPS-GATCICPEGKY-MMNGTC---HDDSL-LDDSCKL 4219
Query: 13588 -CTNGGKCRL----DGSCECTSDFEGDQCE 13662
C NGG+C L D C C + G +CE
Sbjct: 4220 TCENGGRCILNEKGDLRCHCWPSYSGGRCE 4249
Score = 368 bits (945), Expect = 2e-99
Identities = 280/1030 (27%), Positives = 459/1030 (44%), Gaps = 39/1030 (3%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWX-XXXXXXXXXXXXXXXXPHPGCKS-DQWQCDTYTWHSVSCI 330
C + F C +G+CI T W P C+ Q+ C S CI
Sbjct: 927 CQADQFSCGNGRCIPTAWLCDREDDCGDQTDEVASCEFPTCEPLTQFIC-----KSGRCI 981
Query: 331 AEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSD 510
+ CD DC D SDE C S +D + F C+ GR C CDG DC D SD
Sbjct: 982 SNKWHCDTDDDCGDRSDEVGCVHSCLD----DQFRCSSGR-CIPGHWACDGDNDCGDFSD 1036
Query: 511 EKD-SC----SRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPD------TCE 657
E +C +R+ C +F+C CI W CDG KDC DGSDE C+
Sbjct: 1037 ETHINCTKEEARSPAGCIGNEFQCRPDGNCIPDLWRCDGEKDCEDGSDEKGCNGTIRLCD 1096
Query: 658 FKKCTANEFQCKNK-RCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPG-TGHCID 831
K +F C++ RC + CD DC D SDE++C + C P K+ C T C+
Sbjct: 1097 HK----TKFSCRSTGRCINNAWVCDGDVDCEDQSDEEDCDSFLCGPPKYPCANDTSVCLQ 1152
Query: 832 QLKLCDGSKDCADGADE----QQCSQNLCPSLGCQAGCHPSP-HGGECTCPSGYKLDDRF 996
KLC+G KDC DG+DE +CS N + GC C P G C+CP G++L +
Sbjct: 1153 PEKLCNGRKDCPDGSDEGDLCDECSLN---NGGCSNHCSVVPGRGIVCSCPEGHQL-KKD 1208
Query: 997 HRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNA 1176
+RTC ++ CA C Q+C + CSC + + L G D + C S ++
Sbjct: 1209 NRTCEIVDYCASHLRCSQVCEQQKHMVKCSCY-EGWAL------GTDGES----CTSVDS 1257
Query: 1177 DKMKLFVARREGLYRLNPKNPDEEVKKLASG-EFIYGIDFDYGDRKIFWTDRLAHSAFSA 1353
+ + + R + R++ D + L G +DF + ++WTD + +
Sbjct: 1258 FEAFIIFSIRHEIRRIDLHKGDYSL--LVPGLRNTIALDFHFNQSLLYWTDVVEDRIYRG 1315
Query: 1354 DVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLAD 1533
+ + G +S I+ + L P L VDWI +Y I+S +I+VS DG R L+A
Sbjct: 1316 KLSESGGVSAIEVVVEHGLATPEGLTVDWIAGNIYWIDSNLDQIEVSKLDGSLRATLIAG 1375
Query: 1534 GLTLPLDIALDPLRGEMFFT----NQLKLEAAAMDGTNRRTLVNTHTHQV--SGIVVDIT 1695
+ P IALDP G +F+T N ++E+A+M G R+T+ +G+ VD
Sbjct: 1376 AMEHPRAIALDPRYGILFWTDWDANFPRIESASMSGAGRKTIYKDMKTGAWPNGLTVDHF 1435
Query: 1696 AKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQV 1875
+R+ W D + D + S Y G + + +G + HPF ++L+ +YWTDW + +
Sbjct: 1436 ERRIVWTDARSDAIYSAFYDGTNMIEIIRGHEYLSHPFAVSLYGSEVYWTDWRTNTLAKA 1495
Query: 1876 EKF-GSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCIL 2052
K+ G + ++ + + P + YHP QP + C A + PC++ +C++
Sbjct: 1496 NKWTGQNVSVI---QKTSAQPFDLQIYHPSRQP-QAPNPCAANEGRGPCSH-----LCLI 1546
Query: 2053 SKDNGGFGVGYKCACPIGQKLVNGKR-CIDSIDYLLFSSNKIVRGI---FPEINEKALAE 2220
+ + CACP KL + K+ C + +LL++ +RG+ P +N
Sbjct: 1547 NHNRSA-----ACACPHLMKLSSDKKTCYEMKKFLLYARRSEIRGVDIDNPYVNF----- 1596
Query: 2221 AVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLF 2400
I+ + I ++ D ++ DI TI R +G G V+ +
Sbjct: 1597 ----ITAFTVPDIDDVAVIDFDASEERLYWTDIKTQTITRAFINGTGLETVISRDIQSIR 1652
Query: 2401 SMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKGL 2580
++ DW+S+ LY++ + + ++ + D ++ +I + P + HP +G
Sbjct: 1653 GLAVDWVSRNLYWISSEFDETQI------NVARLDGSLKTSIIHGIDKPQCLAAHPVRGK 1706
Query: 2581 LFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDF 2760
L++ + I ++DG N +++ P ++ID+ EN+L W + TI+ +
Sbjct: 1707 LYWTDG---NTINMANMDGSNSKILFQNQ-KEPVGLSIDYVENKLYWISSGNGTINRCNL 1762
Query: 2761 DGKN---VVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVRE--FGAD 2925
DG N + + + A+TIM++ +++ Q + +K++G I+R G
Sbjct: 1763 DGGNLEVIESMKEELTKATALTIMDKKLWWADQNLAQLGTCNKRDGRNPSILRNKTSGVV 1822
Query: 2926 ERSIFSLKACSHQNQPIPDDSREHPCRASQ--CTQLCFATPSESHPNELEAKCACRQGFM 3099
++ +A N C+ + C+QLC T +E C C G+
Sbjct: 1823 HMKVYDKEAQQGSNS----------CQVNNGGCSQLCLPT------SETTRTCMCTVGYY 1866
Query: 3100 INKENNHSCQ 3129
+ K N SCQ
Sbjct: 1867 LQK-NRMSCQ 1875
Score = 281 bits (718), Expect = 4e-73
Identities = 211/760 (27%), Positives = 320/760 (41%), Gaps = 81/760 (10%)
Frame = +1
Query: 139 NTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHS 318
N C DF C++G C+ + + C DQ+QC +
Sbjct: 3509 NCKPQTCTLKDFLCSNGDCVSSRFWCDGEFDCADGSDEKNC-ETSCSKDQFQCS-----N 3562
Query: 319 VSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCR 498
C++ +CD DC G DEK+C + CSS +MCA G C S KC+G+ DC
Sbjct: 3563 GQCLSAKWKCDGHEDCKYGEDEKNCEPAFPVCSSSE-YMCASGG-CLSASLKCNGEPDCV 3620
Query: 499 DLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEF--KKCT 672
D SDE D C + QF+C +K CI W+CDG DC DGSDE +TC C
Sbjct: 3621 DGSDEMDCVIE----CKEDQFQCKNKAYCIPIRWLCDGIYDCVDGSDE-ETCGRGGSICR 3675
Query: 673 ANEFQCKNKRCQPRKFRCDYYDDCGDNSDE--DECGEYRCPPGK-WNCPGTGHCIDQLKL 843
+EF C N C+ + CD DDCGDNSDE D C ++ CPP + + C C+ K+
Sbjct: 3676 DDEFLCNNSLCKLHFWVCDGEDDCGDNSDEAPDMCVKFLCPPTRPYRCRNDRICLQLEKI 3735
Query: 844 CDGSKDCADGADEQQCSQNL-------------CPSLGC------------------QAG 930
C+G DC D +DE+ CS L C + C + G
Sbjct: 3736 CNGINDCGDNSDEEHCSGKLSLKSKPCKKDEFTCSNRNCIPMELQCDSLDDCGDGSDEQG 3795
Query: 931 CHPSP--HGGE--------------------CTCPSGYKLDDRFHRTCSDINECAEFGYC 1044
C +P H E C C G++ + + R C+D+NEC FG C
Sbjct: 3796 CLKTPIEHTCENNGNPCGDDAYCNQIKTSVFCRCKPGFQRNMK-GRECADLNECLLFGIC 3854
Query: 1045 DQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGL--- 1215
C N R + C C ++ K+N C++ ++ L++A +
Sbjct: 3855 SHHCLNTRGSYKCVC--------DQNFQEKNNS-----CIAKGSEDQALYIANDTDILGF 3901
Query: 1216 -YRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKK 1392
Y N +++ + I G+D Y I W+ + + D E Q
Sbjct: 3902 VYPFNYSGGHQQISHVEHNSRITGMDVHYQRNVIVWSTQFNPGGIFYKMIDAREKRQANS 3961
Query: 1393 -LSLKSLVYPRCLAVDWITNTLYIIESGSRR---------------IDVSSYDGERRTVL 1524
L PR +AVDW+ +Y + I+V +G T L
Sbjct: 3962 GLICPEFKRPRDIAVDWVAGNVYWTDHSRMHWFSYYTTHWTSLRYSINVGQLNGPNCTRL 4021
Query: 1525 LADGLTLPLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDIT 1695
L + P IA++P RG M++T + +E AAMDGT RR LV + + +G+ VD
Sbjct: 4022 LTNMAGEPYAIAVNPKRGMMYWTVIGDHSHIEEAAMDGTLRRVLVQKNLQRPTGLTVDHF 4081
Query: 1696 AKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQV 1875
+R+YW D ++ + S+ Y G+ + + HP + +F+ Y+Y + G+ +V
Sbjct: 4082 GERIYWADFELSIIGSVLYDGSSPVVSVSSKQGLLHPHRIDVFEDYIYGAG-PKNGIFRV 4140
Query: 1876 EKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILS 2055
+KFG + V +G+ + + + NPC + C+ +C+L+
Sbjct: 4141 QKFGHGSV--------EVLALGVDKTKSILV----SHRYKQLNLPNPCLDLSCDFLCLLN 4188
Query: 2056 KDNGGFGVGYKCACPIGQKLVNGKRCIDSIDYLLFSSNKI 2175
G C CP G+ ++NG C D D LL S K+
Sbjct: 4189 PS------GATCICPEGKYMMNG-TCHD--DSLLDDSCKL 4219
Score = 276 bits (706), Expect = 1e-71
Identities = 200/673 (29%), Positives = 301/673 (44%), Gaps = 25/673 (3%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKS--DQWQCDTY-TWHSVSC 327
C EN F C G+CI W C+ D+ CD+ +W+ +C
Sbjct: 2682 CEENYFGCPSGRCILNTWVCDG--------------QKDCEDGLDELHCDSSCSWNQFAC 2727
Query: 328 -----IAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYD 492
I+++ CD DC D DE D V C++ ++F C C CDG+ D
Sbjct: 2728 SVKKCISKHWICDGEDDCGDSLDESDSICGAVTCAA-DMFSCQGSHACVPQHWLCDGERD 2786
Query: 493 CRDLSDEKDS--CSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKK 666
C D SDE S C+ N+T C + F C +K CI K +VCD DC DGSDE C +++
Sbjct: 2787 CPDGSDELSSAGCAPNNT-CDENAFMCHNKV-CIPKQFVCDHDDDCGDGSDEFLQCGYRQ 2844
Query: 667 CTANEFQCKNKRCQPRK-FRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGT------GHC 825
C EF+C + RC ++CD DC D+SDE RC + +C + G C
Sbjct: 2845 CGPEEFRCADGRCLVNTLWQCDGDFDCPDSSDEAPINP-RCRSAEHSCNSSFFMCKNGRC 2903
Query: 826 IDQLKLCDGSKDCADGADEQQCSQNLCPS---LGCQAGCHPSPHGGECTCPSGYKLDDRF 996
I LCD DC DG+DE C N C S GC C P +C C G++L D
Sbjct: 2904 IPSDGLCDIRDDCGDGSDETNCHINECLSKKISGCSQDCQDLPVSYKCKCWPGFQLKDD- 2962
Query: 997 HRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNA 1176
+TC DI+EC+ C Q C N + C C + + Q ++ G C S +
Sbjct: 2963 GKTCVDIDECSSGFPCSQQCINTYGTYKCHC-AEGYETQPDNPNG---------CRSLSD 3012
Query: 1177 DKMKLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTD--RLAHSAFS 1350
++ L +A + + +++ + + K I +DFDY + I+W D R S +
Sbjct: 3013 EEPFLILADQHEIRKISTDGSNYTLLKQGLNNVI-ALDFDYREEFIYWIDSSRPNGSRIN 3071
Query: 1351 ADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLA 1530
+ +I + ++ P LAVDWI LY ++ R I+VS +G TVL++
Sbjct: 3072 RMCLNGSDIKVVHNTAV-----PNALAVDWIGKNLYWSDTEKRIIEVSKLNGLYPTVLVS 3126
Query: 1531 DGLTLPLDIALDPLRGEMFFTNQLK---LEAAAMDGTNRRTLVNTHTHQVSGIVVDITAK 1701
L P D++LDP G +++ + + + MDGTN+ ++ T + + +D
Sbjct: 3127 KRLKFPRDLSLDPRAGNLYWIDCCEYPHIGRVGMDGTNQSVVIETKISRPMALTIDYVNH 3186
Query: 1702 RVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEK 1881
R+YW D + +E + G+ R V +P L LF+ Y+YWTD + +V K
Sbjct: 3187 RLYWADE--NHIEFSNMDGSHRHKVPN--QDIPGVIALTLFEDYIYWTDGKTKSLSRVHK 3242
Query: 1882 FGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKD 2061
+L N+ + + I YH QP + C N C +C+L
Sbjct: 3243 TSGADRLSLINSWHAI--TDIQVYHSYRQPDVSKHLCTV-------NNGGCSHLCLL--- 3290
Query: 2062 NGGFGVGYKCACP 2100
G G + CACP
Sbjct: 3291 --GPGKTHTCACP 3301
Score = 174 bits (440), Expect = 7e-41
Identities = 98/257 (38%), Positives = 123/257 (47%), Gaps = 1/257 (0%)
Frame = +1
Query: 124 ISASVNTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXX-PHPGCKSDQWQCD 300
++A T S C + FRC KCI W P C+ ++QC
Sbjct: 3306 LAADNRTCLSNCTASQFRCKTDKCIPFWWKCDTVDDCGDGSDEPDDCPEFKCQPGRFQCG 3365
Query: 301 TYTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCD 480
T C CD DC D SDE +C T C + F C ++C V+ +C+
Sbjct: 3366 TGL-----CALPAFICDGENDCGDNSDELNC--DTHVCLAGQ-FKCTKNKKCIPVNLRCN 3417
Query: 481 GKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEF 660
G+ DC D DEKD C N +C F+C CI K WVCD DCAD SDE + C+
Sbjct: 3418 GQDDCGDEEDEKD-CPEN--SCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEAN-CDK 3473
Query: 661 KKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLK 840
K C +EFQCKN C P +RCD +DC DNSDED C C + C G C+
Sbjct: 3474 KTCGPHEFQCKNNNCIPDHWRCDNQNDCSDNSDEDNCKPQTCTLKDFLC-SNGDCVSSRF 3532
Query: 841 LCDGSKDCADGADEQQC 891
CDG DCADG+DE+ C
Sbjct: 3533 WCDGEFDCADGSDEKNC 3549
Score = 167 bits (423), Expect = 7e-39
Identities = 152/596 (25%), Positives = 241/596 (39%), Gaps = 35/596 (5%)
Frame = +1
Query: 9190 QPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECNKGEFRCSNQHCIHSTWECDGDN 9369
Q ++ C P +LC VT C+ +W CDGD
Sbjct: 27 QDQHLCDPGEFLCHDHVT------------------------------CVSQSWLCDGDP 56
Query: 9370 DCLDGSDEHANC----TYSSCQPDFFQC-ANHKCVPNSWKCDGNDDCEDGSDE-KDCPKN 9531
DC D SDE + C + C + CV S C+G DC DG DE C +
Sbjct: 57 DCPDQSDESLDTCPEEVEIKCPLNHIACHGSSACVHLSKLCNGVVDCPDGFDEGGHCQEL 116
Query: 9532 SASAQKASKCSNGQFQC------TSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAE 9693
S Q+ N QF+C T C D +V + C D+ DECS+
Sbjct: 117 LPSCQQL----NCQFKCAMVRNATRCYCEDGFEVAEDGRSCKDQ---------DECSI-- 161
Query: 9694 KPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCG 9873
+C Q C + Y C C EG+ + SD +SC
Sbjct: 162 YGICSQTCKNTYGSYACSCVEGYIMQ-SDNRSC--------------------------- 193
Query: 9874 CVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKY-ELAAQGFDNVVSLDID 10050
K + P L+++ I I+G+K L++ + + +LD
Sbjct: 194 ------------KVKHEPTDKAPMLLISSLETIELFYINGSKMTTLSSANRNEIHTLDFI 241
Query: 10051 LTEKKAYLIDQGK----------LRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDWV 10200
+E+ I+ + + R+ + + L S++ V E +A DW+
Sbjct: 242 YSEEMICWIESRESSNQLKCGQITKAGRLTDQRIINSLQSFQNV--------EQMAFDWL 293
Query: 10201 GRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFFTEWSLQPYIGR 10380
R +Y ++ I VC +G C TLI + PKAI P G LFFT++ P I R
Sbjct: 294 TRNIYFVDHVSDRIFVCNFNGSVCVTLIESELHNPKAIAADPIAGKLFFTDYGNVPKIER 353
Query: 10381 IALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHI- 10557
LDG + ++ AE P+A+A+D + ++W D +L+ +G +D+ G R I
Sbjct: 354 CDLDGMNRTR-IVYSKAEQ----PSALALDLVNRLVYWVDLYLDYVGVVDYQGKNRHTIV 408
Query: 10558 PAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKN-ETILKKTVQLPNDLRIVHPMR 10734
++ H+ + VF+DYLY + ++R +++ G + +I+K ++ +R
Sbjct: 409 QGRQVKHLYGITVFEDYLYATSSDNFNIIRINRFNGTDIHSIIK--MESARGIRTYQKRT 466
Query: 10735 QP----------AYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTCE 10872
QP AY P GGCSH+CL+ + TC C F + SD ++C+
Sbjct: 467 QPTVRSHACEVDAYGMP-----GGCSHICLLSSSYKTRTCRCRTGFNMGSDGRSCK 517
Score = 143 bits (361), Expect = 1e-31
Identities = 117/374 (31%), Positives = 154/374 (40%), Gaps = 35/374 (9%)
Frame = +1
Query: 142 TASSVCN-ENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQ--WQCDTYTW 312
T +S CN ++F C +G C+ PH KSD+ C+ +
Sbjct: 2505 TKNSSCNIYSEFECGNGDCV------------DYVLTCDGIPHCKDKSDEKLLYCENRSC 2552
Query: 313 HSV-------SCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSK 471
S C+ + CD DC D SDE DC ST CS+ F CADG C S
Sbjct: 2553 RSGFKPCYNRRCVPHGKLCDGTNDCGDSSDELDCKVST--CSTVE-FRCADGT-CIPRSA 2608
Query: 472 KCDGKYDCRDLSDEKDSCSRNHTACFQYQ---------FRCADKTQCIQKSWVCDGSKDC 624
+C+ DC D SDEK N+T C + RC + C+ SW+CDGS DC
Sbjct: 2609 RCNQNMDCSDASDEKGC---NNTDCTHFYKLGVKSTGFIRCNSTSLCVLPSWICDGSNDC 2665
Query: 625 ADGSDEPDTCEFK---KCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPG 795
D SDE C + KC N F C + RC + CD DC D DE C + C
Sbjct: 2666 GDYSDEL-KCPVQNKHKCEENYFGCPSGRCILNTWVCDGQKDCEDGLDELHC-DSSCSWN 2723
Query: 796 KWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLGCQA---------GCHPSPH 948
++ C CI + +CDG DC D DE S ++C ++ C A C P
Sbjct: 2724 QFAC-SVKKCISKHWICDGEDDCGDSLDE---SDSICGAVTCAADMFSCQGSHACVPQHW 2779
Query: 949 --GGECTCPSGYKLDDRFHRTCSDINECAEFGYC--DQLCANHRPGFTCSCLGDCFTLQM 1116
GE CP G D+ C+ N C E + +++C + F C DC
Sbjct: 2780 LCDGERDCPDG--SDELSSAGCAPNNTCDENAFMCHNKVCIPKQ--FVCDHDDDC----- 2830
Query: 1117 EHGPGKDNLTMRGY 1158
G G D GY
Sbjct: 2831 --GDGSDEFLQCGY 2842
Score = 119 bits (297), Expect = 3e-24
Identities = 81/244 (33%), Positives = 99/244 (40%), Gaps = 44/244 (18%)
Frame = +1
Query: 502 LSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANE 681
L+ + +C N TA QFRC +CI W CD DC DGSDEPD C KC
Sbjct: 3306 LAADNRTCLSNCTAS---QFRCKTD-KCIPFWWKCDTVDDCGDGSDEPDDCPEFKCQPGR 3361
Query: 682 FQC----------------------------------------KNKRCQPRKFRCDYYDD 741
FQC KNK+C P RC+ DD
Sbjct: 3362 FQCGTGLCALPAFICDGENDCGDNSDELNCDTHVCLAGQFKCTKNKKCIPVNLRCNGQDD 3421
Query: 742 CGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLGC 921
CGD DE +C E C P + C T HCI +L +CD DCAD +DE C + C
Sbjct: 3422 CGDEEDEKDCPENSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEANCDKKTC----- 3476
Query: 922 QAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCD----QLCANHRPGFTCSC 1089
PH E C + + D H C + N+C++ D Q C F CS
Sbjct: 3477 ------GPH--EFQCKNNNCIPD--HWRCDNQNDCSDNSDEDNCKPQTCT--LKDFLCS- 3523
Query: 1090 LGDC 1101
GDC
Sbjct: 3524 NGDC 3527
Score = 88.2 bits (217), Expect = 5e-15
Identities = 49/149 (32%), Positives = 73/149 (48%), Gaps = 6/149 (4%)
Frame = +1
Query: 478 DGKYDCRDLSDE----KDSCSRNHTACFQY-QFRCADKTQCIQKSWVCDGSKDCADGSDE 642
DG+ +C D + C +++C Y +F C + C+ CDG C D SDE
Sbjct: 2484 DGRVNCSCRGDRVLLANNRCVTKNSSCNIYSEFECGNG-DCVDYVLTCDGIPHCKDKSDE 2542
Query: 643 PDT-CEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTG 819
CE + C + C N+RC P CD +DCGD+SDE +C C ++ C G
Sbjct: 2543 KLLYCENRSCRSGFKPCYNRRCVPHGKLCDGTNDCGDSSDELDCKVSTCSTVEFRC-ADG 2601
Query: 820 HCIDQLKLCDGSKDCADGADEQQCSQNLC 906
CI + C+ + DC+D +DE+ C+ C
Sbjct: 2602 TCIPRSARCNQNMDCSDASDEKGCNNTDC 2630
Score = 79.0 bits (193), Expect = 3e-12
Identities = 50/141 (35%), Positives = 66/141 (46%), Gaps = 4/141 (2%)
Frame = +1
Query: 643 PDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDE--CGEYRCPPGKWNCPGT 816
P+ F C EF+CKNK C +++CD DDC D SDED C + CP ++ C
Sbjct: 837 PEEIRFHICKPGEFRCKNKHCIQARWKCDGDDDCLDGSDEDSVTCFNHSCPDDQFKCQ-N 895
Query: 817 GHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLD--D 990
CI + LCDG+ DC DE S C + CQA S G C P+ + D D
Sbjct: 896 NRCIPKRWLCDGANDCGSNEDE---SNQTCTARTCQAD-QFSCGNGRC-IPTAWLCDRED 950
Query: 991 RFHRTCSDINECAEFGYCDQL 1053
++ C EF C+ L
Sbjct: 951 DCGDQTDEVASC-EFPTCEPL 970
Score = 68.6 bits (166), Expect = 4e-09
Identities = 111/500 (22%), Positives = 184/500 (36%), Gaps = 62/500 (12%)
Frame = +1
Query: 7429 NLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAENPRLVFGASKQPHAKEIRHISDMKL 7608
N + +DV+ +R V + ++ M +A R P K R D+ +
Sbjct: 3920 NSRITGMDVHYQRNVIVWSTQFNPGGIFYKMIDAREKRQANSGLICPEFKRPR---DIAV 3976
Query: 7609 DWLTQKIYFT-----------TGRGGKVMAIDTAGE-------HLSTIASGDWTYALAID 7734
DW+ +Y+T T + G+ L T +G+ YA+A++
Sbjct: 3977 DWVAGNVYWTDHSRMHWFSYYTTHWTSLRYSINVGQLNGPNCTRLLTNMAGE-PYAIAVN 4035
Query: 7735 PCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVDFRNQKIYWA 7914
P G+++W+ G + IE + + G R+V+V +++ P + VD ++IYWA
Sbjct: 4036 PKRGMMYWTVIGDHS-------HIEEAAMDGTLRRVLVQKNLQRPTGLTVDHFGERIYWA 4088
Query: 7915 DVNRLNIEVADYDGQNRKVIASGYRA----KSLDIWDRWLYMSDPLSNGVFRIDKESGSG 8082
D I YDG + V S + +D+++ ++Y + P NG+FR+ K
Sbjct: 4089 DFELSIIGSVLYDGSSPVVSVSSKQGLLHPHRIDVFEDYIYGAGP-KNGIFRVQKFGHGS 4147
Query: 8083 LENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLC-------TVVA 8241
+E + ++ V + N + LC + G +C
Sbjct: 4148 VEVLALGVDKTKSILVSHRYKQLNLPNPCLDLSCDFLCLLNPSGATCICPEGKYMMNGTC 4207
Query: 8242 DDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSEPAKECLPPYNFQCGDGSCI- 8418
D L + +C + + D +C S S E N+ G+CI
Sbjct: 4208 HDDSLLDDSCKLTCENGGRCILNEKGD--LRCHCWPSYSGGRCEVNHCSNYCQNGGTCIP 4265
Query: 8419 --LLGATC-----DSKPDCADASDE--------------NPNYCNTRSCPEDYNLCTNRR 8535
L TC + P+C A E N YC+ C DY T R
Sbjct: 4266 STLGRPTCICALGFTGPNCGKAVCEDSCHNGGSCVVTAGNQPYCH---CQADY---TGDR 4319
Query: 8536 CIDSAKKCNHI----DDC---GDGSDELDCPS---AVAC-AEGTFPCSNGHCINQTKVCD 8682
C C+H + C DGS E CP+ C + C GHCI D
Sbjct: 4320 C--QYYVCHHYCVNSESCTIGNDGSVECVCPTRYEGPKCEIDKCVRCHGGHCIINKDNED 4377
Query: 8683 GHNDCHDEQVSDESLATCPG 8742
+C + +++ S C G
Sbjct: 4378 IFCNCTNGKIA-SSCQLCDG 4396
Score = 65.1 bits (157), Expect = 5e-08
Identities = 86/334 (25%), Positives = 137/334 (40%), Gaps = 18/334 (5%)
Frame = +1
Query: 2404 MSFDWISKQLYYVDNIR-----------NSLEV-VKIGETGLVHPDELVRRQLITELRDP 2547
++ DW++ +Y+ D+ R SL + +G+ L P+ R L +P
Sbjct: 3974 IAVDWVAGNVYWTDHSRMHWFSYYTTHWTSLRYSINVGQ--LNGPN--CTRLLTNMAGEP 4029
Query: 2548 VSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGD 2727
++ V+P +G++++ + I +DG +V+ L RP+ + +D R+ W D
Sbjct: 4030 YAIAVNPKRGMMYWTVIGDHSHIEEAAMDGTLRRVLVQKNLQRPTGLTVDHFGERIYWAD 4089
Query: 2728 TLLKTISCMDFDGKN-VVKLDIDNPI--PVAITIMNEYIYYVHQRPYSIRRVHKKNGGGS 2898
L I + +DG + VV + + P I + +YIY + I RV +K G GS
Sbjct: 4090 FELSIIGSVLYDGSSPVVSVSSKQGLLHPHRIDVFEDYIYGAGPK-NGIFRV-QKFGHGS 4147
Query: 2899 KIVREFGADE-RSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAK 3075
V G D+ +SI N P +PC C LC PS A
Sbjct: 4148 VEVLALGVDKTKSILVSHRYKQLNLP-------NPCLDLSCDFLCLLNPS-------GAT 4193
Query: 3076 CACRQG-FMINKENNHSCQKDPAEKIEQLCSSNSTQFQCKN-GRCIPKEWKCDGENDCLD 3249
C C +G +M+ N +C D +S + C+N GRCI E K D C
Sbjct: 4194 CICPEGKYMM----NGTCHDDS-------LLDDSCKLTCENGGRCILNE-KGDLRCHCWP 4241
Query: 3250 ESDEIDEKGDKCFHETECAENTIKCRNTKKCIPA 3351
G +C E + C+N CIP+
Sbjct: 4242 -----SYSGGRC----EVNHCSNYCQNGGTCIPS 4266
Score = 63.9 bits (154), Expect = 1e-07
Identities = 57/255 (22%), Positives = 109/255 (42%), Gaps = 20/255 (7%)
Frame = +1
Query: 12967 KKIVAGHLQQPTALITAPSAGRICYSD------AGLHAKIECADMDGTHRQIIVKDLVFS 13128
K ++ G + P A++ P G + ++D +IE A MDG +RQ+ V +
Sbjct: 637 KTLLEGGMSHPRAIVVDPVNGWMYWTDWKEDKIDDSVGRIEKAWMDGVNRQVFVTSKMLW 696
Query: 13129 PTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHI--PYAVDVFENHIYWLS 13302
P + +D + +YW D Y ++ V ++G+ R V + + P+ + N+++W
Sbjct: 697 PNGLTLD-FHTSTLYWCDAYYDHIEKVFLNGTHRKVVYSGKELNHPFGLSHHGNYVFWTD 755
Query: 13303 RESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGC--ERAQCSHLCVS 13476
+ +++ D V++L + +++ Y Q+ + C C LC++
Sbjct: 756 YMNGSIFQLDLM-TNEVTLLRHERAPLFGLQI---YDPRKQQGDNMCRINNGGCGTLCLA 811
Query: 13477 LPSTGFACLCPDGIVPQLDGSCATQHVEALTM----PKQCKCTN------GGKCRLDGSC 13626
+P+ G C C D + +G+ T + E + P + +C N KC D C
Sbjct: 812 IPA-GRVCACADNQLLDENGTTCTFNPEEIRFHICKPGEFRCKNKHCIQARWKCDGDDDC 870
Query: 13627 ECTSDFEGDQCEKES 13671
SD + C S
Sbjct: 871 LDGSDEDSVTCFNHS 885
Score = 59.7 bits (143), Expect = 2e-06
Identities = 48/152 (31%), Positives = 61/152 (39%), Gaps = 10/152 (6%)
Frame = +1
Query: 271 GCKSDQWQCDT--YTWHS-VSCIAEYQRCDNITDCADGSDEK--DCPASTVDCSSQNVFM 435
G DQ CD + H V+C+++ CD DC D SDE CP N
Sbjct: 24 GANQDQHLCDPGEFLCHDHVTCVSQSWLCDGDPDCPDQSDESLDTCPEEVEIKCPLNHIA 83
Query: 436 CADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQY--QFRCA---DKTQCIQKSW 600
C C +SK C+G DC D DE C +C Q QF+CA + T+C +
Sbjct: 84 CHGSSACVHLSKLCNGVVDCPDGFDEGGHCQELLPSCQQLNCQFKCAMVRNATRC----Y 139
Query: 601 VCDGSKDCADGSDEPDTCEFKKCTANEFQCKN 696
DG + DG D E CKN
Sbjct: 140 CEDGFEVAEDGRSCKDQDECSIYGICSQTCKN 171
>gi|38074796|ref|XP_130308.2| similar to low density lipoprotein
receptor-related protein 2; glycoprotein 330; low density
lipoprotein-related protein 2; megalin [Mus musculus]
Length = 3312
Score = 1851 bits (4795), Expect = 0.0
Identities = 1090/3230 (33%), Positives = 1654/3230 (50%), Gaps = 73/3230 (2%)
Frame = +1
Query: 4192 RDLCSADRAGCSFKCHNSPNGPICSCPFGEQLVNKTK-CEPENECLDSSSCSQRCKDEKH 4368
+D C GC+ +C P G C CP G QL N TK CE NEC CSQ C + +
Sbjct: 3 QDSCLHFNGGCTHRCIQGPFGATCVCPIGYQLANDTKTCEDVNECDIPGFCSQHCVNMRG 62
Query: 4369 GFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGAIVENA-- 4542
F C+CD Y L+ D RTCKV + ++ + V++R++I D+ + H ++V++
Sbjct: 63 SFRCACDPEYTLESDGRTCKVTAS-ENLLLVVASRDKIIM-DNITAHTHNIYSLVQDVSF 120
Query: 4543 -IALAWDSLTDRIYWSDIREKKILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVD 4719
+AL +DS+T R++WSD+ E K SA +NGT+ V GL +TE IA+DW+GRN+YW D
Sbjct: 121 VVALDFDSVTGRVFWSDLLEGKTWSAFQNGTDKRVVHDSGLSLTEMIAVDWIGRNIYWTD 180
Query: 4720 SSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKG--VMFWTDWGQNPCIERASMDG 4893
+L TIEV+ + D RT+L+ +NV++PRG+A+DPR G VMFW+DWG +P IERASMDG
Sbjct: 181 YTLETIEVSKI-DGSHRTVLISKNVTKPRGLALDPRMGDNVMFWSDWGHHPRIERASMDG 239
Query: 4894 TDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPH 5073
T R +IV+ KIYWP +++DY +YF D+ LD+I+F +YDG R QV+AS + HPH
Sbjct: 240 TMRTVIVQEKIYWPCGLSIDYPNRLIYFMDAYLDYIEFCDYDGQNRRQVIASDLVLHHPH 299
Query: 5074 ALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPC 5253
AL +FED ++++DR ++ K+ +G ++ + LG++A+HP QP NPC
Sbjct: 300 ALTLFEDSVFWTDRGTHQVMQANKW-HGRNQSVVMYSVPQPLGIIAIHPSRQPS-SPNPC 357
Query: 5254 STNPCSHLCLLNNKNT--FTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNVFGIEMNSA 5427
++ CSHLCLL+ + ++C CP G L C+ +PFL+ +++ +FGI +
Sbjct: 358 ASATCSHLCLLSAQEPRHYSCACPSGWNLSDDSVNCVRGDQPFLISVRENVIFGISL--- 414
Query: 5428 SEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNG 5607
+ E MVP+SG+ + +D +D + ++ +E+ I+R +G
Sbjct: 415 -DPEVKSNDAMVPISGIQHGYDVEFDDSEQFIYWVENPGE------------IHRVKTDG 461
Query: 5608 GNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGK-QYRSVILSNDQSXX 5784
N+T ++ + L DW RN+ +++IE++ +G +Y +++ND +
Sbjct: 462 SNRTAFAPLSLLGSSLGLALDWVSRNIYYTTPASRSIEVLTLRGDTRYGKTLITNDGTPL 521
Query: 5785 XXXXXXXXXXXXXKGYVFWLDRG-GGAADAKVARAGLDGSNPLVIASNDLAELDHIAIDT 5961
+G ++W D G AK+A A +DG++ ++ + ++ L+ + +D
Sbjct: 522 GVGFPVGIAVDPARGKLYWSDHGTDSGVPAKIASANMDGTSLKILFTGNMEHLEVVTLDI 581
Query: 5962 TNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAFDSIEVAT 6141
++Y++ G I DG +R +L P GL +G L+Y+D ++ IE
Sbjct: 582 QEQKLYWAVTSRGVIERGNVDGTER-MILVHHLAHPWGLVVHGSFLYYSDEQYEVIERVD 640
Query: 6142 INGDSQPPQWTHFKKDVENLANIKALQPR-ASSSGHPCHINNGNCDHICIPLMFAQRTCT 6318
+ S F+ ++ L ++ R A+ S + C N C IC+P+ +C
Sbjct: 641 KSSGSNK---VVFRDNIPYLRGLRVYHHRNAADSSNGCSNNPNACQQICLPVPGGMFSCA 697
Query: 6319 CANGYV--KDGQTSCKLFDESFVIVATKTKVIGYPIDETQSKGVAMEPIGGL--SITGVD 6486
CA+G+ DG+ SC ++ SF++V+ V G+ + E AM P+ G ++ D
Sbjct: 698 CASGFKLSPDGR-SCSPYN-SFIVVSMLPAVRGFSL-ELSDHSEAMVPVAGQGRNVLHAD 754
Query: 6487 YDYESKTIYVAEASGI---NKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINYNMYF 6657
D + IY + S + GI S+ ++ IG+ I+ +A+DW+ N+YF
Sbjct: 755 VDVANGFIYWCDFSSSVRSSNGIRRIKPNGSNFTNIVTYGIGANGIRGVAVDWVAGNLYF 814
Query: 6658 INHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQRSFLD 6837
N T IEV +++ TYR++LL + P I VDP RYL+WAD GQKP I+RSFLD
Sbjct: 815 TNAFVYETLIEVIRINTTYRRVLLKVSVDMPRHIVVDPKHRYLFWADYGQKPKIERSFLD 874
Query: 6838 GSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPELVR--SDIASAA 7011
+ R V+VS GI P L VD + IYW D +D I R+ GG ++VR S +
Sbjct: 875 CTNRTVLVSEGIVTPRGLAVDHDTGYIYWVDDSLDIIARIHRDGGESQVVRYGSRYPTPY 934
Query: 7012 GVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRAS 7191
G+ + G+++ W D L K+F+A+ +P T PT + S+ + DV +F + QP
Sbjct: 935 GITVFGESIIWVDRNLRKVFQASKQPGNTD---PPTVIRDSINLLRDVTIFDEHVQPL-- 989
Query: 7192 SPCQITDN---LRKSPCTQLCFATPGTQTPTCSCARGVLK--GRTCEEP-DTYIMFSDGD 7353
SP ++ +N C+ CFA P TP C CA G L+ G+ C + ++++S +
Sbjct: 990 SPAELNNNPCLQSNGGCSHFCFALPELPTPKCGCAFGTLEDDGKNCATSREDFLIYSLNN 1049
Query: 7354 KIIDVAIEPDVKASRPLKDPFPEIS---NLQTFDVDVNLRRVYFVVE-SPVGVNISWFSM 7521
+ + +P + PF IS D D R++F + +P+ IS+ ++
Sbjct: 1050 SLRSLHFDP-----QDHNLPFQAISVEGMAIALDYDRRNNRIFFTQKLNPIRGQISYVNL 1104
Query: 7522 -NNAENPRLVFGASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTI 7698
+ A +P ++ I + DW+ ++IY++ + ++ G + + I
Sbjct: 1105 YSGASSPTILLS--------NIGVTDGIAFDWINRRIYYSDFSNQTINSMAEDGSNRAVI 1156
Query: 7699 ASGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAI 7878
A A+ +DPC G ++W+D G +IER+ L G R IV+ S+ P +
Sbjct: 1157 ARVSKPRAIVLDPCRGYMYWTDWGTNA-------KIERATLGGNFRVPIVNTSLVWPNGL 1209
Query: 7879 AVDFRNQKIYWADVNRLNIEVADYDGQNRKVIAS-GYRAKSLDIWDRWLYMSDPLSNGVF 8055
+D +YWAD + IE + G NR+V+ S + + L ++ +++Y +D + ++
Sbjct: 1210 TLDLETDLLYWADASLQKIERSTLTGSNREVVISTAFHSFGLTVYGQYIYWTDFYTKKIY 1269
Query: 8056 RIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLCTV 8235
R +K GS L + R+P + + V+T+ Q C S C NGGC +C
Sbjct: 1270 RANKYDGSDL--IAMTTRLP--TQPSGISTVVKTQQQQC----SNPCDQFNGGCSHICAP 1321
Query: 8236 VADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSEPAKECLPPYNFQCGDGSC 8415
G ++ QC ++ L + CV+ + C + F C +G C
Sbjct: 1322 -----GPNGAECQCPHEGSWYLANDN-----KYCVV-----DTGARC-NQFQFTCLNGRC 1365
Query: 8416 ILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHIDDCGDGSDE 8595
I CD+ DC D SDE P C +C C N RC+ +C+ +DCGD SDE
Sbjct: 1366 ISQDWKCDNDNDCGDGSDELPTVCAFHTCRSTAFTCANGRCVPYHYRCDFYNDCGDNSDE 1425
Query: 8596 LDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPGLPIDCRGVKVR 8775
C + F CSNG CI + VC+G N+CHD SDE CP PI C+ +
Sbjct: 1426 AGCLFRSCNSTTEFTCSNGRCIPLSYVCNGINNCHDNDTSDEK--NCP--PITCQPDFAK 1481
Query: 8776 CPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSG-RCIPETWQCDGDN 8952
C TNIC+ A LCDG +DCGD +DEN ++C + C + +C S RCIP W CDG+
Sbjct: 1482 CQTTNICVPRAFLCDGDNDCGDGSDENPIYCASHTCRSNEFQCVSPHRCIPSYWFCDGEA 1541
Query: 8953 DCSDGWDETHTNCTDTAGKKI--CVGDYLFQCDNLKCISRAFIXXXXXXXXXXXXXHSRH 9126
DC D DE DT G + C + F CDN +CIS +++ RH
Sbjct: 1542 DCVDSSDEP-----DTCGHSLNSCSANQ-FHCDNGRCISSSWVCDGDNDCGDMSDEDQRH 1595
Query: 9127 GCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECNK 9306
C + C+ EF C ++ P CIP+ W+CDGD CA DE L + C+
Sbjct: 1596 HCELQNCSSTEFTCINSRP---PNRRCIPQHWVCDGDADCADALDE---LQNCTMRACST 1649
Query: 9307 GEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCANHKCVPNSWKCDGN 9486
GEF C+N CI ++ CD NDC D SDE C+Y C+ D F C N +C+ + CD +
Sbjct: 1650 GEFSCANGRCIRQSFRCDRRNDCGDYSDERG-CSYPPCRDDQFTCQNGQCITKLYVCDED 1708
Query: 9487 DDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLC 9666
+DC DGSDE++ ++ C QF+C +G CI+ VC+ DC+D SDE C
Sbjct: 1709 NDCGDGSDEQEHLCHTPEPT----CPPHQFRCDNGHCIEMGTVCNHVDDCSDNSDEKG-C 1763
Query: 9667 FIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNECYEGISGCSQKCD 9846
I+EC + C+ C D + C C G+ + +SD+++C +++EC E CSQKC+
Sbjct: 1764 GINECQDSSISHCDHNCTDTITSFYCSCLPGYKL-MSDKRTCVDIDECKETPQLCSQKCE 1822
Query: 9847 DKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYELAAQGFD 10026
+ IGSY C C GY D SC++ EP+ + +N++YIR ++IDG Y L QG
Sbjct: 1823 NVIGSYICKCAPGYIREPDGKSCRQNS-NIEPYLVFSNRYYIRNLTIDGTSYSLILQGLG 1881
Query: 10027 NVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDWVGR 10206
NVV+LD D E++ Y ID K + R+ L++ ++ ET++ H + E +AVDWV R
Sbjct: 1882 NVVALDFDRVEERLYWIDAEKQIIERMFLNK-----TNQETIISHRLRRAESLAVDWVSR 1936
Query: 10207 KLYMLNRQERSIRVCELDGRFCKTLIRDRI--------QQPKAIVVHPGKGYLFFTEWSL 10362
KLY L+ + V +L+GR K L + + + P+ IV+HP +GY+++ +W
Sbjct: 1937 KLYWLDAILDCLFVSDLEGRQRKMLAQHCVDANNTFCFENPRGIVLHPQRGYVYWADWGD 1996
Query: 10363 QPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGN 10542
YI RI +DG+ + + + WPNAI IDY +D L+W DAHL I F D +G+
Sbjct: 1997 HAYIARIGMDGTNKTV-----IISTKIEWPNAITIDYTNDLLYWADAHLGYIEFSDLEGH 2051
Query: 10543 GRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDLRIV 10722
R + H ++ +F+D ++W DWN R V + +K+ G +L T P D+ ++
Sbjct: 2052 HRHTVYDGTLPHPFALTIFEDTVFWTDWNTRTVEKGNKYDGSGRVVLVNTTHKPFDIHVL 2111
Query: 10723 HPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQF--VLLSDQKTCEPNCTERQF 10896
HP RQP NPC NNGGCSHLCLI AGG G+TC CPD F V L D+ C P C+ QF
Sbjct: 2112 HPYRQPIMSNPCATNNGGCSHLCLIKAGGRGFTCECPDDFQTVQLRDRTLCMPMCSSTQF 2171
Query: 10897 ACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRPFQIXXX 11076
CG ++ KCIP W CDG+ DC DGSDE +C R C +G+FQC + NCT P +
Sbjct: 2172 LCGNNE-KCIPIWWKCDGQKDCSDGSDE--SDLCPHRFCRLGQFQCRDGNCTSPQALCNA 2228
Query: 11077 XXXXXXXXXEQN--CD-KACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEADTLCMSA 11247
E C+ C+ ++C A RCIP + SDE + C A
Sbjct: 2229 RQDCADGSDEDRVLCEHHRCEANEWQC-ANKRCIPEYWQCDSVDDCLDNSDEDPSHC--A 2285
Query: 11248 ERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXE-TPEC--AQIECKKGWT-RCSSSYR 11415
R C +F+CNN +CI ++W+ E EC A C C ++YR
Sbjct: 2286 SRTCRPGQFKCNNGRCIPQSWKCDVDNDCGDYSDEPIHECMTAAYNCDNHTEFSCKTNYR 2345
Query: 11416 CIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSD 11595
CIP WA CNG DDCRDNSDE C G+FRC + CIP RW CD +DCGDNSD
Sbjct: 2346 CIPQWAVCNGFDDCRDNSDEQGCESVPCHPSGDFRCG-NHHCIPLRWKCDGIDDCGDNSD 2404
Query: 11596 ELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQCD 11775
E SC R C+ESEFRC D +CIP VCD C D DE C ++ C P H QC
Sbjct: 2405 E--ESC--VPRECTESEFRCADQQCIPSRWVCDQENDCGDNSDERDCEMKTCHPEHFQCT 2460
Query: 11776 DGTCIAEHKWCDRKKDCPNAADELHCED--VSRRTCSPFEFECANSVCIPRKFMXXXXXX 11949
G C+ + CD + DC +A+DE C + C FEC N VCI ++
Sbjct: 2461 SGHCVPKALACDGRADCLDASDESACPTRFPNGTYCPAAMFECKNHVCIQSFWICDGEND 2520
Query: 11950 XXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSF 12129
SDE C + C+ P RFRC +SR C+ QLCNG +DCG D SDE C
Sbjct: 2521 CVDGSDEEIHLCFNVPCESPQRFRCDNSR-CIYGHQLCNGVDDCG--DGSDEKEEHCRK- 2576
Query: 12130 SEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKH 12309
+ C+ ++KC+NG CV+ CD DDCGD SDE GC+ +T E C+
Sbjct: 2577 PTHKPCTDTEYKCSNGNCVSQHYVCDNVDDCGDLSDETGCNLGENRTCAEKI-----CEQ 2631
Query: 12310 ICTDVRD-GFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGSYLCRCHEDYE 12486
CT + + GF C CR GF+P C DI+EC C Q C N+KGSY C C + ++
Sbjct: 2632 NCTQLSNGGFICSCRPGFKPSTLDKNSCQDINECEEFGICPQSCRNSKGSYECFCVDGFK 2691
Query: 12487 NNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXXX 12666
+ + + G+ C A G +++ + + + ++ + +
Sbjct: 2692 S---MSTHYGERCAADGSPPLLLLPENVRIRKYNISSEKFSEYLEEEEHIQAIDYDWDPE 2748
Query: 12667 XPRKELMYWI---DGSE-RTIYRSAIANGNQSHEGQKLDVDFAAMGVV-PTAIAVDYTTG 12831
++Y+ GS+ I R+ + + +VD ++ P +AVD+
Sbjct: 2749 GIGLSVVYYTVLSQGSQFGAIKRAYLPDFESGSNNPVREVDLGLKYLMQPDGLAVDWVGR 2808
Query: 12832 NLFIA-AVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTAL 13008
+++ + A S+ IE V DGRY K ++ L QP A+
Sbjct: 2809 HIYWSDAKSQRIE------------------------VATLDGRYRKWLITTQLDQPAAI 2844
Query: 13009 ITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPK 13188
P G + ++D G KIE A M+G HR ++ + P ++ID G+RIYW D K
Sbjct: 2845 AVNPKLGLMFWTDQGKQPKIESAWMNGEHRSVLASANLGWPNGLSIDYLNGDRIYWSDSK 2904
Query: 13189 YRRVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSRESKTLYVQDKFGRGR------ 13350
++++ DG++R +++D P+++D+FE+ +YW+++E ++ Q+KFG+G
Sbjct: 2905 EDVIESIKYDGTDRRLIINDAMKPFSLDIFEDQLYWVAKEKGEVWRQNKFGKGNKEKLLV 2964
Query: 13351 VSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTGFACLCPDG--IVP 13524
V+ + + H +R +Q +VS + CSHLC+ P G++C CP G V
Sbjct: 2965 VNPWLTQVRIFHQLRYNQ--------SVSNPCKQVCSHLCLLRPG-GYSCACPQGSDFVT 3015
Query: 13525 QLDGSCATQHVEALTMPKQCKCTNGGKCRLDGS----CECTSDFEGDQCE 13662
C +TMP C+C +GG C D + C+C+S + G+ CE
Sbjct: 3016 GSTVECDAASELPITMPSPCRCMHGGSCYFDENDLPKCKCSSGYSGEYCE 3065
Score = 500 bits (1287), Expect = e-139
Identities = 405/1514 (26%), Positives = 624/1514 (40%), Gaps = 163/1514 (10%)
Frame = +1
Query: 1267 GEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLS---LKSLVYP------ 1419
G + D D + I+W D FS+ V I +IK + Y
Sbjct: 747 GRNVLHADVDVANGFIYWCD------FSSSVRSSNGIRRIKPNGSNFTNIVTYGIGANGI 800
Query: 1420 RCLAVDWITNTLYIIESG--SRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFT 1593
R +AVDW+ LY + I+V + R VLL + +P I +DP +F+
Sbjct: 801 RGVAVDWVAGNLYFTNAFVYETLIEVIRINTTYRRVLLKVSVDMPRHIVVDPKHRYLFWA 860
Query: 1594 N---QLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGND 1764
+ + K+E + +D TNR LV+ G+ VD +YWVD +D + I G +
Sbjct: 861 DYGQKPKIERSFLDCTNRTVLVSEGIVTPRGLAVDHDTGYIYWVDDSLDIIARIHRDGGE 920
Query: 1765 RRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGI 1944
++V G P P+G+ +F + + W D V Q K +T ++ +
Sbjct: 921 SQVVRYGSRY-PTPYGITVFGESIIWVDRNLRKVFQASKQPGNTDPPTVIRDSINLLRDV 979
Query: 1945 SAYHPMAQP-GPGQSECLAMKIENPC--TNADCEGMCILSKDNGGFGVGYKCACPIGQKL 2115
+ + QP P + NPC +N C C + KC C G
Sbjct: 980 TIFDEHVQPLSPAELN------NNPCLQSNGGCSHFCFALPELPT----PKCGCAFGTLE 1029
Query: 2116 VNGKRCIDSI-DYLLFSSNKIVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVH 2292
+GK C S D+L++S N +R + + + L P IS GM ++ D
Sbjct: 1030 DDGKNCATSREDFLIYSLNNSLRSLHFDPQDHNL-----PFQAISVE--GMAIALDYDRR 1082
Query: 2293 GNSFFYADIMD---NTIYRIRPDGEGAAPVLVTHNDGLFS-MSFDWISKQLYYVDNIRNS 2460
N F+ ++ I + ++P ++ N G+ ++FDWI++++YY D +
Sbjct: 1083 NNRIFFTQKLNPIRGQISYVNLYSGASSPTILLSNIGVTDGIAFDWINRRIYYSDFSNQT 1142
Query: 2461 LEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQ 2640
+ + E G R +I + P ++V+ P +G +++ + A I R + G
Sbjct: 1143 IN--SMAEDGS-------NRAVIARVSKPRAIVLDPCRGYMYWTDWGTNAKIERATLGGN 1193
Query: 2641 NCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVKLDIDNPIPVAITI 2820
I NT+L P+ + +D + L W D L+ I G N + +T+
Sbjct: 1194 FRVPIVNTSLVWPNGLTLDLETDLLYWADASLQKIERSTLTGSNREVVISTAFHSFGLTV 1253
Query: 2821 MNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHP 3000
+YIY+ I R +K +G + + S S + Q Q +P
Sbjct: 1254 YGQYIYWTDFYTKKIYRANKYDGSDLIAMTTRLPTQPSGISTVVKTQQQQC------SNP 1307
Query: 3001 CRASQ--CTQLCFATPSESHPNELEAKCAC-RQGFMINKENNHSCQKDPAEKIEQLCSSN 3171
C C+ +C P+ A+C C +G +N C D + Q
Sbjct: 1308 CDQFNGGCSHICAPGPNG-------AECQCPHEGSWYLANDNKYCVVDTGARCNQF---- 1356
Query: 3172 STQFQCKNGRCIPKEWKCDGENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKKCIPA 3351
QF C NGRCI ++WKCD +NDC D SDE+ T CA +T CR+T
Sbjct: 1357 --QFTCLNGRCISQDWKCDNDNDCGDGSDEL---------PTVCAFHT--CRST------ 1397
Query: 3352 QXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXE 3531
F C N RC+P ++ E
Sbjct: 1398 --------------------------------AFTCANGRCVPYHYRCDFYNDCGDNSDE 1425
Query: 3532 K---LEMCGNATCAANQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFR 3702
C + T +F+C+NGRCIP+ ++C+G N+C+D D++ CPP+ C +
Sbjct: 1426 AGCLFRSCNSTT----EFTCSNGRCIPLSYVCNGINNCHDNDTSDEKNCPPITCQPDFAK 1481
Query: 3703 CANGRQCVPLRNHXXXXXXXXXXXXXXXXAVTAESCTPDQFKCVSSGLCIPASWKXXXXX 3882
C CVP + +C ++F+CVS CIP+ W
Sbjct: 1482 CQTTNICVPRAFLCDGDNDCGDGSDENPIYCASHTCRSNEFQCVSPHRCIPSYWFCDGEA 1541
Query: 3883 XXXXXSDEPKFGCTSGRQCSSDQFKCGNGRCILNNWLCDGENDCGDGSDESSERGCKTSM 4062
SDEP S CS++QF C NGRCI ++W+CDG+NDCGD SDE C+
Sbjct: 1542 DCVDSSDEPDTCGHSLNSCSANQFHCDNGRCISSSWVCDGDNDCGDMSDEDQRHHCEL-Q 1600
Query: 4063 NARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGC------ 4224
N F + CIP H +CDG C DE C CS C
Sbjct: 1601 NCSSTEFTCINSRPPNRRCIPQHWVCDGDADCADALDELQNCTMRACSTGEFSCANGRCI 1660
Query: 4225 --SFKC--------HNSPNG---PIC-----SCPFGEQLVNKTKCEPENECLDSS----- 4335
SF+C ++ G P C +C G+ + C+ +N+C D S
Sbjct: 1661 RQSFRCDRRNDCGDYSDERGCSYPPCRDDQFTCQNGQCITKLYVCDEDNDCGDGSDEQEH 1720
Query: 4336 --------------------------------SCS----------QRCKDEK-----HGF 4374
CS C+D H
Sbjct: 1721 LCHTPEPTCPPHQFRCDNGHCIEMGTVCNHVDDCSDNSDEKGCGINECQDSSISHCDHNC 1780
Query: 4375 T-------CSCDEGYELDVDKRTCKVADNVKDT--------------------------- 4452
T CSC GY+L DKRTC D K+T
Sbjct: 1781 TDTITSFYCSCLPGYKLMSDKRTCVDIDECKETPQLCSQKCENVIGSYICKCAPGYIREP 1840
Query: 4453 -----------RIYVSNRNRIYYSDHKLDNWHTFGAIVE---NAIALAWDSLTDRIYWSD 4590
Y+ NR Y + +D ++ I++ N +AL +D + +R+YW D
Sbjct: 1841 DGKSCRQNSNIEPYLVFSNRYYIRNLTIDG-TSYSLILQGLGNVVALDFDRVEERLYWID 1899
Query: 4591 IREKKILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQR 4770
++ I N TN I+ L E +A+DWV R LYW+D+ L+ + V++LE +QR
Sbjct: 1900 AEKQIIERMFLNKTNQETIISHRLRRAESLAVDWVSRKLYWLDAILDCLFVSDLEG-RQR 1958
Query: 4771 TLLVHQNV--------SQPRGIAVDPRKGVMFWTDWGQNPCIERASMDGTDRQIIVKTKI 4926
+L V PRGI + P++G ++W DWG + I R MDGT++ +I+ TKI
Sbjct: 1959 KMLAQHCVDANNTFCFENPRGIVLHPQRGYVYWADWGDHAYIARIGMDGTNKTVIISTKI 2018
Query: 4927 YWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFEDMMYY 5106
WPN I +DYT D +Y+AD+ L +I+F + +G R V + + HP AL IFED +++
Sbjct: 2019 EWPNAITIDYTNDLLYWADAHLGYIEFSDLEGHHRHTVYDGT--LPHPFALTIFEDTVFW 2076
Query: 5107 SDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTN--PCSHLC 5280
+D + ++ KY +G+ +T K + +HP QP++ +NPC+TN CSHLC
Sbjct: 2077 TDWNTRTVEKGNKY-DGSGRVVLVNTTHKPFDIHVLHPYRQPIM-SNPCATNNGGCSHLC 2134
Query: 5281 LLN-NKNTFTCKCP 5319
L+ FTC+CP
Sbjct: 2135 LIKAGGRGFTCECP 2148
Score = 363 bits (931), Expect = 9e-98
Identities = 325/1249 (26%), Positives = 505/1249 (40%), Gaps = 168/1249 (13%)
Frame = +1
Query: 2083 YKCACPIGQ-KLVNGKRCIDSID---YLLFSSNKIVRGIFPEINEKALAEAVLPISPISQ 2250
Y C C G + +GK C + + YL+FS+ +R + + +L
Sbjct: 1828 YICKCAPGYIREPDGKSCRQNSNIEPYLVFSNRYYIRNLTIDGTSYSLI----------L 1877
Query: 2251 RRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWISKQ 2430
+ +G ++ D ++ D I R+ + ++ S++ DW+S++
Sbjct: 1878 QGLGNVVALDFDRVEERLYWIDAEKQIIERMFLNKTNQETIISHRLRRAESLAVDWVSRK 1937
Query: 2431 LYYVDNIRNSLEVVKI-GETGLVHPDELVRRQLITELRDPVSVVVHPWKGLLFYAEAMRP 2607
LY++D I + L V + G + V +P +V+HP +G +++A+
Sbjct: 1938 LYWLDAILDCLFVSDLEGRQRKMLAQHCVDANNTFCFENPRGIVLHPQRGYVYWADWGDH 1997
Query: 2608 AAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVKL- 2784
A I R +DG N VI +T + P+ + ID+ + L W D L I D +G + +
Sbjct: 1998 AYIARIGMDGTNKTVIISTKIEWPNAITIDYTNDLLYWADAHLGYIEFSDLEGHHRHTVY 2057
Query: 2785 DIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQ 2964
D P P A+TI + +++ ++ + +K +G G ++ F +
Sbjct: 2058 DGTLPHPFALTIFEDTVFWTDWNTRTVEKGNKYDGSGRVVLVN---TTHKPFDIHVLHPY 2114
Query: 2965 NQPIPDDSREHPCRASQ--CTQLCFATPSESHPNELEAKCACRQGFM-INKENNHSCQKD 3135
QPI +PC + C+ LC C C F + + C
Sbjct: 2115 RQPI----MSNPCATNNGGCSHLCLIKAGGRG-----FTCECPDDFQTVQLRDRTLCMP- 2164
Query: 3136 PAEKIEQLCSSNSTQFQCKNG-RCIPKEWKCDGENDCLDESDEID--------------- 3267
+CSS TQF C N +CIP WKCDG+ DC D SDE D
Sbjct: 2165 -------MCSS--TQFLCGNNEKCIPIWWKCDGQKDCSDGSDESDLCPHRFCRLGQFQCR 2215
Query: 3268 ----------------------EKGDKCFHETECAENTIKCRNTKKCIPAQXXXXXXXXX 3381
E C H C N +C N K+CIP
Sbjct: 2216 DGNCTSPQALCNARQDCADGSDEDRVLCEHH-RCEANEWQCAN-KRCIPEYWQCDSVDDC 2273
Query: 3382 XXXXXXXVKYCKDGQKPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNA-- 3555
+C C +F+C+N RCIP+ WK E + C A
Sbjct: 2274 LDNSDEDPSHCASR---TCRPGQFKCNNGRCIPQSWKCDVDNDCGDYSDEPIHECMTAAY 2330
Query: 3556 --------TCAAN----------------------------------QFSCANGRCIPIY 3609
+C N F C N CIP+
Sbjct: 2331 NCDNHTEFSCKTNYRCIPQWAVCNGFDDCRDNSDEQGCESVPCHPSGDFRCGNHHCIPLR 2390
Query: 3610 WLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQCVPLRNHXXXXXXXXXXXXXXXX 3789
W CDG +DC D +DE E C P +C+ +FRCA+ +QC+P R
Sbjct: 2391 WKCDGIDDCGDNSDE--ESCVPRECTESEFRCAD-QQCIPSR--WVCDQENDCGDNSDER 2445
Query: 3790 AVTAESCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCT--SGRQCSSDQFKCG 3963
++C P+ F+C +SG C+P + SDE +G C + F+C
Sbjct: 2446 DCEMKTCHPEHFQC-TSGHCVPKALACDGRADCLDASDESACPTRFPNGTYCPAAMFECK 2504
Query: 3964 NGRCILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLCD 4143
N CI + W+CDGENDC DGSDE + + C+N + CI HQLC+
Sbjct: 2505 NHVCIQSFWICDGENDCVDGSDEEIHLCFNVPCESP----QRFRCDNSR--CIYGHQLCN 2558
Query: 4144 GKTHCPGGTDE---------------------GGRCAR--------DLCS--ADRAGCSF 4230
G C G+DE G C D C +D GC+
Sbjct: 2559 GVDDCGDGSDEKEEHCRKPTHKPCTDTEYKCSNGNCVSQHYVCDNVDDCGDLSDETGCNL 2618
Query: 4231 -------------KCHNSPNGP-ICSC--PFGEQLVNKTKCEPENECLDSSSCSQRCKDE 4362
C NG ICSC F ++K C+ NEC + C Q C++
Sbjct: 2619 GENRTCAEKICEQNCTQLSNGGFICSCRPGFKPSTLDKNSCQDINECEEFGICPQSCRNS 2678
Query: 4363 KHGFTCSCDEGYE-----------LDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDN 4509
K + C C +G++ D + +NV+ + +S+ +S++ +
Sbjct: 2679 KGSYECFCVDGFKSMSTHYGERCAADGSPPLLLLPENVRIRKYNISSEK---FSEYLEEE 2735
Query: 4510 WHTFGAIVENAIALAWDSL---TDRIYWSDIRE--------KKILSANRNGTNATVFIAD 4656
H AI WD +Y++ + + + L +G+N V D
Sbjct: 2736 EHI------QAIDYDWDPEGIGLSVVYYTVLSQGSQFGAIKRAYLPDFESGSNNPVREVD 2789
Query: 4657 -GLDI---TEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDP 4824
GL +G+A+DWVGR++YW D+ IEVA L D + R L+ + QP IAV+P
Sbjct: 2790 LGLKYLMQPDGLAVDWVGRHIYWSDAKSQRIEVATL-DGRYRKWLITTQLDQPAAIAVNP 2848
Query: 4825 RKGVMFWTDWGQNPCIERASMDGTDRQIIVKTKIYWPNTIALDYTT-DRVYFADSKLDFI 5001
+ G+MFWTD G+ P IE A M+G R ++ + WPN +++DY DR+Y++DSK D I
Sbjct: 2849 KLGLMFWTDQGKQPKIESAWMNGEHRSVLASANLGWPNGLSIDYLNGDRIYWSDSKEDVI 2908
Query: 5002 DFVNYDGSGRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSH 5181
+ + YDG+ R ++ + P +L IFED +Y+ + +K +V+ + G ++
Sbjct: 2909 ESIKYDGTDRRLIINDA---MKPFSLDIFEDQLYWVAK--EKGEVWRQNKFGKGNKEKLL 2963
Query: 5182 TFSKALGVVAV-HPVLQPVIKNNPCSTNPCSHLCLLNNKNTFTCKCPMG 5325
+ L V + H + +NPC CSHLCLL ++C CP G
Sbjct: 2964 VVNPWLTQVRIFHQLRYNQSVSNPCK-QVCSHLCLL-RPGGYSCACPQG 3010
Score = 290 bits (743), Expect = 5e-76
Identities = 212/685 (30%), Positives = 308/685 (44%), Gaps = 33/685 (4%)
Frame = +1
Query: 169 DFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAEYQRC 348
DFRC + CI W C +++C CI C
Sbjct: 2378 DFRCGNHHCIPLRWKCDGIDDCGDNSDEESCVPRECTESEFRCADQ-----QCIPSRWVC 2432
Query: 349 DNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCS 528
D DC D SDE+DC T C ++ F C G C + CDG+ DC D SDE +
Sbjct: 2433 DQENDCGDNSDERDCEMKT--CHPEH-FQCTSGH-CVPKALACDGRADCLDASDESACPT 2488
Query: 529 R--NHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEP-DTCEFKKCTANE-FQCKN 696
R N T C F C + CIQ W+CDG DC DGSDE C C + + F+C N
Sbjct: 2489 RFPNGTYCPAAMFECKNHV-CIQSFWICDGENDCVDGSDEEIHLCFNVPCESPQRFRCDN 2547
Query: 697 KRCQPRKFRCDYYDDCGDNSDEDE--CGEYR---CPPGKWNCPGTGHCIDQLKLCDGSKD 861
RC C+ DDCGD SDE E C + C ++ C G+C+ Q +CD D
Sbjct: 2548 SRCIYGHQLCNGVDDCGDGSDEKEEHCRKPTHKPCTDTEYKC-SNGNCVSQHYVCDNVDD 2606
Query: 862 CADGADEQQCS---QNLCPSLGCQAGCHPSPHGGE-CTCPSGYKLDDRFHRTCSDINECA 1029
C D +DE C+ C C+ C +GG C+C G+K +C DINEC
Sbjct: 2607 CGDLSDETGCNLGENRTCAEKICEQNCTQLSNGGFICSCRPGFKPSTLDKNSCQDINECE 2666
Query: 1030 EFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVAR-R 1206
EFG C Q C N + + C C+ ++ +G C ++ + + L R
Sbjct: 2667 EFGICPQSCRNSKGSYECFCVDGFKSMSTHYGER---------CAADGSPPLLLLPENVR 2717
Query: 1207 EGLYRLNPKNPDEEVKKLASGEFIYGIDFDY-----GDRKIFWTDRLAHSAFSADVD--- 1362
Y ++ + E +++ E I ID+D+ G +++T S F A
Sbjct: 2718 IRKYNISSEKFSEYLEE---EEHIQAIDYDWDPEGIGLSVVYYTVLSQGSQFGAIKRAYL 2774
Query: 1363 ---DEGEISQIKK--LSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLL 1527
+ G + +++ L LK L+ P LAVDW+ +Y ++ S+RI+V++ DG R L+
Sbjct: 2775 PDFESGSNNPVREVDLGLKYLMQPDGLAVDWVGRHIYWSDAKSQRIEVATLDGRYRKWLI 2834
Query: 1528 ADGLTLPLDIALDPLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHTHQVSGIVVD-IT 1695
L P IA++P G MF+T+ Q K+E+A M+G +R L + + +G+ +D +
Sbjct: 2835 TTQLDQPAAIAVNPKLGLMFWTDQGKQPKIESAWMNGEHRSVLASANLGWPNGLSIDYLN 2894
Query: 1696 AKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQV 1875
R+YW D K D +ESI Y G DRR++ +N PF L +F+ LYW + V +
Sbjct: 2895 GDRIYWSDSKEDVIESIKYDGTDRRLI---INDAMKPFSLDIFEDQLYWVAKEKGEVWRQ 2951
Query: 1876 EKF--GSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCI 2049
KF G+ KLL N + + +H + + NPC C +C+
Sbjct: 2952 NKFGKGNKEKLLVVNP----WLTQVRIFHQLR---------YNQSVSNPCKQV-CSHLCL 2997
Query: 2050 LSKDNGGFGVGYKCACPIGQKLVNG 2124
L GY CACP G V G
Sbjct: 2998 LRPG------GYSCACPQGSDFVTG 3016
Score = 278 bits (711), Expect = 3e-72
Identities = 196/677 (28%), Positives = 285/677 (41%), Gaps = 68/677 (10%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQ 453
C+S+++QC + CI Y CD DC D SDE D +++ S N F C +GR
Sbjct: 1517 CRSNEFQCVS----PHRCIPSYWFCDGEADCVDSSDEPDTCGHSLNSCSANQFHCDNGR- 1571
Query: 454 CFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKT----QCIQKSWVCDGSKD 621
C S CDG DC D+SDE C +F C + +CI + WVCDG D
Sbjct: 1572 CISSSWVCDGDNDCGDMSDEDQRHHCELQNCSSTEFTCINSRPPNRRCIPQHWVCDGDAD 1631
Query: 622 CADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDE------------- 762
CAD DE C + C+ EF C N RC + FRCD +DCGD SDE
Sbjct: 1632 CADALDELQNCTMRACSTGEFSCANGRCIRQSFRCDRRNDCGDYSDERGCSYPPCRDDQF 1691
Query: 763 -----------------DECG-------------EYRCPPGKWNCPGTGHCIDQLKLCDG 852
++CG E CPP ++ C GHCI+ +C+
Sbjct: 1692 TCQNGQCITKLYVCDEDNDCGDGSDEQEHLCHTPEPTCPPHQFRCDN-GHCIEMGTVCNH 1750
Query: 853 SKDCADGADEQQCSQNLCPSLG---CQAGCHPSPHGGECTCPSGYKL-DDRFHRTCSDIN 1020
DC+D +DE+ C N C C C + C+C GYKL D+ RTC DI+
Sbjct: 1751 VDDCSDNSDEKGCGINECQDSSISHCDHNCTDTITSFYCSCLPGYKLMSDK--RTCVDID 1808
Query: 1021 ECAEFGY-CDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFV 1197
EC E C Q C N + C C PG C N+ + L
Sbjct: 1809 ECKETPQLCSQKCENVIGSYICKC-----------APGYIREPDGKSCRQNSNIEPYLVF 1857
Query: 1198 ARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTD---RLAHSAFSADVDDE 1368
+ R + L + G + +DFD + +++W D ++ F + E
Sbjct: 1858 SNRYYIRNLTIDGTSYSLILQGLGNVV-ALDFDRVEERLYWIDAEKQIIERMFLNKTNQE 1916
Query: 1369 GEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTL- 1545
IS L LAVDW++ LY +++ + VS +G +R +L +
Sbjct: 1917 TIISH-------RLRRAESLAVDWVSRKLYWLDAILDCLFVSDLEGRQRKMLAQHCVDAN 1969
Query: 1546 -------PLDIALDPLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDIT 1695
P I L P RG +++ + + MDGTN+ +++T + I +D T
Sbjct: 1970 NTFCFENPRGIVLHPQRGYVYWADWGDHAYIARIGMDGTNKTVIISTKIEWPNAITIDYT 2029
Query: 1696 AKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQV 1875
+YW D + +E D +G+ R V G +PHPF L +F+ ++WTDW V +
Sbjct: 2030 NDLLYWADAHLGYIEFSDLEGHHRHTVYDG--TLPHPFALTIFEDTVFWTDWNTRTVEKG 2087
Query: 1876 EKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPC--TNADCEGMCI 2049
K+ +++ NT + P I HP QP + NPC N C +C+
Sbjct: 2088 NKYDGSGRVVLVNTTHK--PFDIHVLHPYRQP----------IMSNPCATNNGGCSHLCL 2135
Query: 2050 LSKDNGGFGVGYKCACP 2100
+ G G+ C CP
Sbjct: 2136 IKAG----GRGFTCECP 2148
Score = 258 bits (658), Expect = 4e-66
Identities = 209/762 (27%), Positives = 339/762 (44%), Gaps = 25/762 (3%)
Frame = +1
Query: 916 GCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLG 1095
GC C P G C CP GY+L + +TC D+NEC G+C Q C N R F C+C
Sbjct: 12 GCTHRCIQGPFGATCVCPIGYQLANDT-KTCEDVNECDIPGFCSQHCVNMRGSFRCACDP 70
Query: 1096 DCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKLASG-E 1272
+ +TL+ D T C ++ + L VA R+ + N + L
Sbjct: 71 E-YTLE------SDGRT----CKVTASENLLLVVASRDKIIMDNITAHTHNIYSLVQDVS 119
Query: 1273 FIYGIDFDYGDRKIFWTDRLAHSAFSADVDD-EGEISQIKKLSLKSLVYPRCLAVDWITN 1449
F+ +DFD ++FW+D L +SA + + + LSL ++ AVDWI
Sbjct: 120 FVVALDFDSVTGRVFWSDLLEGKTWSAFQNGTDKRVVHDSGLSLTEMI-----AVDWIGR 174
Query: 1450 TLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGE--MFFTN---QLKLEA 1614
+Y + I+VS DG RTVL++ +T P +ALDP G+ MF+++ ++E
Sbjct: 175 NIYWTDYTLETIEVSKIDGSHRTVLISKNVTKPRGLALDPRMGDNVMFWSDWGHHPRIER 234
Query: 1615 AAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNV 1794
A+MDGT R +V + G+ +D + +Y++D +D +E DY G +RR V V
Sbjct: 235 ASMDGTMRTVIVQEKIYWPCGLSIDYPNRLIYFMDAYLDYIEFCDYDGQNRRQVIASDLV 294
Query: 1795 VPHPFGLALFDQYLYWTDWTRLGVIQVEKF-GSDTKLLWSNTENNVFPMGISAYHPMAQP 1971
+ HP L LF+ ++WTD V+Q K+ G + ++ + P+GI A HP QP
Sbjct: 295 LHHPHALTLFEDSVFWTDRGTHQVMQANKWHGRNQSVVMYSVPQ---PLGIIAIHPSRQP 351
Query: 1972 GPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGK-RCI-DSI 2145
NPC +A C +C+LS Y CACP G L + C+
Sbjct: 352 SS----------PNPCASATCSHLCLLSAQEPRH---YSCACPSGWNLSDDSVNCVRGDQ 398
Query: 2146 DYLLFSSNKIVRGIF--PEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADI 2319
+L+ ++ GI PE+ +A++PIS I ++VE D F Y
Sbjct: 399 PFLISVRENVIFGISLDPEVKSN---DAMVPISGIQHG-----YDVEFD-DSEQFIYWVE 449
Query: 2320 MDNTIYRIRPDGEGA---APVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETG 2490
I+R++ DG AP+ + + ++ DW+S+ +YY S+EV+ +
Sbjct: 450 NPGEIHRVKTDGSNRTAFAPLSLLGSS--LGLALDWVSRNIYYTTPASRSIEVLTL---- 503
Query: 2491 LVHPDELVRRQLITE------LRDPVSVVVHPWKGLLFYA----EAMRPAAIYRCHIDGQ 2640
D + LIT + PV + V P +G L+++ ++ PA I ++DG
Sbjct: 504 --RGDTRYGKTLITNDGTPLGVGFPVGIAVDPARGKLYWSDHGTDSGVPAKIASANMDGT 561
Query: 2641 NCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVKLDIDNPIPVAITI 2820
+ +++ + + +D E +L W T I + DG + L P + +
Sbjct: 562 SLKILFTGNMEHLEVVTLDIQEQKLYWAVTSRGVIERGNVDGTERMILVHHLAHPWGLVV 621
Query: 2821 MNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHP 3000
++YY ++ I RV K +G + R+ + + L+ H+N D S
Sbjct: 622 HGSFLYYSDEQYEVIERVDKSSGSNKVVFRD---NIPYLRGLRVYHHRN--AADSSNGCS 676
Query: 3001 CRASQCTQLCFATPSESHPNELEAKCACRQGFMINKENNHSC 3126
+ C Q+C P CAC GF ++ + SC
Sbjct: 677 NNPNACQQICLPVPGGMF------SCACASGFKLSPD-GRSC 711
Score = 174 bits (440), Expect = 7e-41
Identities = 107/309 (34%), Positives = 140/309 (44%), Gaps = 13/309 (4%)
Frame = +1
Query: 145 ASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVS 324
AS C F+CN+G+CI W P C + + CD +T S
Sbjct: 2285 ASRTCRPGQFKCNNGRCIPQSW---KCDVDNDCGDYSDEPIHECMTAAYNCDNHTEFSCK 2341
Query: 325 ----CIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYD 492
CI ++ C+ DC D SDE+ C +V C F C + C + KCDG D
Sbjct: 2342 TNYRCIPQWAVCNGFDDCRDNSDEQGC--ESVPCHPSGDFRCGN-HHCIPLRWKCDGIDD 2398
Query: 493 CRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCT 672
C D SDE+ R C + +FRCAD+ QCI WVCD DC D SDE D CE K C
Sbjct: 2399 CGDNSDEESCVPRE---CTESEFRCADQ-QCIPSRWVCDQENDCGDNSDERD-CEMKTCH 2453
Query: 673 ANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDEC------GEYRCPPGKWNCPGTGHCIDQ 834
FQC + C P+ CD DC D SDE C G Y CP + C CI
Sbjct: 2454 PEHFQCTSGHCVPKALACDGRADCLDASDESACPTRFPNGTY-CPAAMFECK-NHVCIQS 2511
Query: 835 LKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGEC---TCPSGYKLDDRFHRT 1005
+CDG DC DG+DE+ +LC ++ C+ SP C C G H+
Sbjct: 2512 FWICDGENDCVDGSDEE---IHLCFNVPCE-----SPQRFRCDNSRCIYG-------HQL 2556
Query: 1006 CSDINECAE 1032
C+ +++C +
Sbjct: 2557 CNGVDDCGD 2565
Score = 164 bits (414), Expect = 8e-38
Identities = 113/372 (30%), Positives = 148/372 (39%), Gaps = 55/372 (14%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAE 336
CN+ F C +G+CI +W C + +T + C+
Sbjct: 1353 CNQFQFTCLNGRCISQDWKCDNDNDCGDGSDELPTV---CAFHTCRSTAFTCANGRCVPY 1409
Query: 337 YQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGR------------QCFDVSKK-- 474
+ RCD DC D SDE C + C+S F C++GR C D
Sbjct: 1410 HYRCDFYNDCGDNSDEAGCLFRS--CNSTTEFTCSNGRCIPLSYVCNGINNCHDNDTSDE 1467
Query: 475 ---------------------------CDGKYDCRDLSDEKDSCSRNHTACFQYQFRCAD 573
CDG DC D SDE +HT C +F+C
Sbjct: 1468 KNCPPITCQPDFAKCQTTNICVPRAFLCDGDNDCGDGSDENPIYCASHT-CRSNEFQCVS 1526
Query: 574 KTQCIQKSWVCDGSKDCADGSDEPDTC--EFKKCTANEFQCKNKRCQPRKFRCDYYDDCG 747
+CI W CDG DC D SDEPDTC C+AN+F C N RC + CD +DCG
Sbjct: 1527 PHRCIPSYWFCDGEADCVDSSDEPDTCGHSLNSCSANQFHCDNGRCISSSWVCDGDNDCG 1586
Query: 748 DNSDEDE---CGEYRCPPGKWNC----PGTGHCIDQLKLCDGSKDCADGADE-QQCSQNL 903
D SDED+ C C ++ C P CI Q +CDG DCAD DE Q C+
Sbjct: 1587 DMSDEDQRHHCELQNCSSTEFTCINSRPPNRRCIPQHWVCDGDADCADALDELQNCTMRA 1646
Query: 904 CPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRP---- 1071
C + GE +C +G + F C N+C + Y D+ ++ P
Sbjct: 1647 CST-------------GEFSCANGRCIRQSFR--CDRRNDCGD--YSDERGCSYPPCRDD 1689
Query: 1072 GFTCSCLGDCFT 1107
FTC G C T
Sbjct: 1690 QFTCQ-NGQCIT 1700
Score = 156 bits (395), Expect = 1e-35
Identities = 94/302 (31%), Positives = 129/302 (42%), Gaps = 45/302 (14%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTE--WXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCI 330
C F+C DG C + H C++++WQC + CI
Sbjct: 2207 CRLGQFQCRDGNCTSPQALCNARQDCADGSDEDRVLCEHHRCEANEWQCA-----NKRCI 2261
Query: 331 AEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSD 510
EY +CD++ DC D SDE ++ C F C +GR C S KCD DC D SD
Sbjct: 2262 PEYWQCDSVDDCLDNSDEDPSHCASRTCRPGQ-FKCNNGR-CIPQSWKCDVDNDCGDYSD 2319
Query: 511 E----------------KDSCSRNHTACFQY---------------------------QF 561
E + SC N+ Q+ F
Sbjct: 2320 EPIHECMTAAYNCDNHTEFSCKTNYRCIPQWAVCNGFDDCRDNSDEQGCESVPCHPSGDF 2379
Query: 562 RCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDD 741
RC + CI W CDG DC D SDE ++C ++CT +EF+C +++C P ++ CD +D
Sbjct: 2380 RCGNH-HCIPLRWKCDGIDDCGDNSDE-ESCVPRECTESEFRCADQQCIPSRWVCDQEND 2437
Query: 742 CGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLGC 921
CGDNSDE +C C P + C +GHC+ + CDG DC D +DE C C
Sbjct: 2438 CGDNSDERDCEMKTCHPEHFQCT-SGHCVPKALACDGRADCLDASDESACPTRFPNGTYC 2496
Query: 922 QA 927
A
Sbjct: 2497 PA 2498
Score = 142 bits (357), Expect = 3e-31
Identities = 94/259 (36%), Positives = 118/259 (45%), Gaps = 8/259 (3%)
Frame = +1
Query: 154 VCNENDFRC-NDGKCIRTEWXXXXXXXXXXXXXXXXX-PHPGCKSDQWQCDTYTWHSVSC 327
+C+ F C N+ KCI W PH C+ Q+QC +C
Sbjct: 2165 MCSSTQFLCGNNEKCIPIWWKCDGQKDCSDGSDESDLCPHRFCRLGQFQC-----RDGNC 2219
Query: 328 IAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLS 507
+ C+ DCADGSDE C + N + CA+ R C +CD DC D S
Sbjct: 2220 TSPQALCNARQDCADGSDEDRVLCEHHRCEA-NEWQCANKR-CIPEYWQCDSVDDCLDNS 2277
Query: 508 DEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPD----TCEFKKCTA 675
DE S + T C QF+C + +CI +SW CD DC D SDEP T +
Sbjct: 2278 DEDPSHCASRT-CRPGQFKC-NNGRCIPQSWKCDVDNDCGDYSDEPIHECMTAAYNCDNH 2335
Query: 676 NEFQCK-NKRCQPRKFRCDYYDDCGDNSDEDECGEYRC-PPGKWNCPGTGHCIDQLKLCD 849
EF CK N RC P+ C+ +DDC DNSDE C C P G + C G HCI CD
Sbjct: 2336 TEFSCKTNYRCIPQWAVCNGFDDCRDNSDEQGCESVPCHPSGDFRC-GNHHCIPLRWKCD 2394
Query: 850 GSKDCADGADEQQCSQNLC 906
G DC D +DE+ C C
Sbjct: 2395 GIDDCGDNSDEESCVPREC 2413
Score = 119 bits (299), Expect = 2e-24
Identities = 85/240 (35%), Positives = 106/240 (43%), Gaps = 16/240 (6%)
Frame = +1
Query: 376 SDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQY 555
+D K C T +Q F C +GR C KCD DC D SDE + HT C
Sbjct: 1340 NDNKYCVVDTGARCNQFQFTCLNGR-CISQDWKCDNDNDCGDGSDELPTVCAFHT-CRST 1397
Query: 556 QFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTAN-EFQCKNKRCQPRKFRCDY 732
F CA+ +C+ + CD DC D SDE C F+ C + EF C N RC P + C+
Sbjct: 1398 AFTCANG-RCVPYHYRCDFYNDCGDNSDEAG-CLFRSCNSTTEFTCSNGRCIPLSYVCNG 1455
Query: 733 YDDCGDN--SDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQ--QCSQN 900
++C DN SDE C C P C T C+ + LCDG DC DG+DE C+ +
Sbjct: 1456 INNCHDNDTSDEKNCPPITCQPDFAKCQTTNICVPRAFLCDGDNDCGDGSDENPIYCASH 1515
Query: 901 LCPSLGCQAGCHPSPH---------GGECTCPSGYKLDDRFHRTCS-DINEC-AEFGYCD 1047
C S Q SPH GE C D TC +N C A +CD
Sbjct: 1516 TCRSNEFQC---VSPHRCIPSYWFCDGEADCVDSSDEPD----TCGHSLNSCSANQFHCD 1568
Score = 114 bits (286), Expect = 5e-23
Identities = 67/187 (35%), Positives = 86/187 (45%), Gaps = 7/187 (3%)
Frame = +1
Query: 544 CFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFR 723
C QF C + +CI W CDG KDC+DGSDE D C + C +FQC++ C +
Sbjct: 2166 CSSTQFLCGNNEKCIPIWWKCDGQKDCSDGSDESDLCPHRFCRLGQFQCRDGNCTSPQAL 2225
Query: 724 CDYYDDCGDNSDEDE--CGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQ 897
C+ DC D SDED C +RC +W C CI + CD DC D +DE
Sbjct: 2226 CNARQDCADGSDEDRVLCEHHRCEANEWQC-ANKRCIPEYWQCDSVDDCLDNSDE---DP 2281
Query: 898 NLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSD-----INECAEFGYCDQLCAN 1062
+ C S C+ G + G C P +K D C D I+EC Y C N
Sbjct: 2282 SHCASRTCRPGQFKC-NNGRC-IPQSWKCD--VDNDCGDYSDEPIHECMTAAY---NCDN 2334
Query: 1063 HRPGFTC 1083
H F+C
Sbjct: 2335 HTE-FSC 2340
Score = 68.6 bits (166), Expect = 4e-09
Identities = 57/222 (25%), Positives = 82/222 (36%), Gaps = 15/222 (6%)
Frame = +1
Query: 139 NTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHS 318
N C+ +F C +G+CIR + +P C+ DQ+ C +
Sbjct: 1641 NCTMRACSTGEFSCANGRCIRQSFRCDRRNDCGDYSDERGCSYPPCRDDQFTC-----QN 1695
Query: 319 VSCIAEYQRCDNITDCADGSDEKD--CPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYD 492
CI + CD DC DGSDE++ C C F C +G C ++ C+ D
Sbjct: 1696 GQCITKLYVCDEDNDCGDGSDEQEHLCHTPEPTCPPHQ-FRCDNG-HCIEMGTVCNHVDD 1753
Query: 493 CRDLSDEKDSCSRNH---TACFQYQFRCADK-----TQCIQKSWVCDGSKDCAD---GSD 639
C D SDEK C N ++ C D C+ + + C D +
Sbjct: 1754 CSDNSDEK-GCGINECQDSSISHCDHNCTDTITSFYCSCLPGYKLMSDKRTCVDIDECKE 1812
Query: 640 EPDTCEFKKC--TANEFQCKNKRCQPRKFRCDYYDDCGDNSD 759
P C +KC + CK C P R C NS+
Sbjct: 1813 TPQLCS-QKCENVIGSYICK---CAPGYIREPDGKSCRQNSN 1850
Score = 37.7 bits (86), Expect = 8.3
Identities = 31/96 (32%), Positives = 38/96 (39%), Gaps = 8/96 (8%)
Frame = +1
Query: 880 EQQCSQNLCPSL--GCQAGCHPSPHGGECTCP---SGYKLDDRFHRTCSDINECAEFGYC 1044
+QQCS N C GC C P P+G EC CP S Y +D + C +F +
Sbjct: 1301 QQQCS-NPCDQFNGGCSHICAPGPNGAECQCPHEGSWYLANDNKYCVVDTGARCNQFQF- 1358
Query: 1045 DQLCANHR---PGFTCSCLGDCFTLQMEHGPGKDNL 1143
C N R + C DC G G D L
Sbjct: 1359 --TCLNGRCISQDWKCDNDNDC-------GDGSDEL 1385
>gi|34854634|ref|XP_346657.1| hypothetical protein XP_346656 [Rattus
norvegicus]
Length = 2994
Score = 1568 bits (4059), Expect = 0.0
Identities = 999/3135 (31%), Positives = 1523/3135 (47%), Gaps = 100/3135 (3%)
Frame = +1
Query: 5152 NGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTNPCSHLCLLNNK--NTFTCKCPMG 5325
+G ++ + LG+ A+HP QP +N PC++ CSHLCLL+ + ++C CP G
Sbjct: 7 HGGNQSVVMYSVHQPLGITAIHPSRQPPSRN-PCASASCSHLCLLSAQAPRHYSCACPSG 65
Query: 5326 EKLDASGKKCIDDAKPFLVIIQKTNVFGIEMNSASEKETPVLAGMVPLSGLGNAFDAAYD 5505
L C+ +PFL+ ++ +FGI + + E MVP+SG+ + +D +D
Sbjct: 66 WNLSDDSVNCVRGDQPFLMSVRDNIIFGISL----DPEVKSNDAMVPISGIQHGYDVEFD 121
Query: 5506 ALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRN 5685
+ ++ +E+ I+R +G N+T ++ + L DW RN
Sbjct: 122 DSEQFIYWVENPGE------------IHRVKTDGSNRTVFAPLSLLGSSLGLALDWVSRN 169
Query: 5686 LVVGNKITQTIEIIRTQGK-QYRSVILSNDQSXXXXXXXXXXXXXXXKGYVFWLDRG-GG 5859
+ +++IE++ +G +Y +++ND + +G ++W D G
Sbjct: 170 IYYTTPASRSIEVLTLKGDTRYGKTLIANDGTPLGVGFPVGIAVDPARGKLYWSDHGTDS 229
Query: 5860 AADAKVARAGLDGSNPLVIASNDLAELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRH 6039
AK+A A +DG++ ++ + +L L+ + +D ++Y++ G I DG +R
Sbjct: 230 GVPAKIASANMDGTSLKILFTGNLQHLEVVTLDIQEQKLYWAVTSRGVIERGNVDGTER- 288
Query: 6040 YVLSDGGRQPNGLAFYGDRLFYADSAFDSIE-VATINGDSQPPQWTHFKKDVENLANIKA 6216
+L P GL YG L+Y+D ++ IE V +G+++ + +V L ++
Sbjct: 289 MILVHHLAHPWGLVVYGSFLYYSDEQYEVIERVDKSSGNNK----VVLRDNVPYLRGLRV 344
Query: 6217 LQPR-ASSSGHPCHINNGNCDHICIPLMFAQRTCTCANGYV--KDGQTSCKLFDESFVIV 6387
R A+ S + C N C IC+P+ +C CA+G+ DG+ SC ++ SF++V
Sbjct: 345 YHRRNAADSSNGCSNNPNACQQICLPVPGGMFSCACASGFKLSPDGR-SCSPYN-SFMVV 402
Query: 6388 ATKTKVIGYPIDETQSKGVAMEPIGGL--SITGVDYDYESKTIYVAEASGI---NKGITA 6552
+ V G+ + E AM P+ G ++ D D + IY + S + GI
Sbjct: 403 SMLPAVRGFSL-ELSDHSEAMVPVAGQGRNVLHADVDVANGFIYWCDFSSSVRSSNGIRR 461
Query: 6553 YTIGESSPRAVIRDSIGSLTIKSLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLT 6732
S+ V+ IG+ I+ +A+DW N+YF N T IEV +++ TYR++LL
Sbjct: 462 IKPDGSNFTNVVTYGIGANGIRGVALDWAAGNLYFTNAFVYETLIEVLRINTTYRRVLLK 521
Query: 6733 TKTETPSSIAVDPVSRYLYWADQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASK 6912
+ P I VDP RYL+WAD GQKP I+RSFLD + R V+VS GI P L +D +
Sbjct: 522 VSVDMPRHIIVDPKHRYLFWADYGQKPKIERSFLDCTNRTVLVSEGIVTPRGLAMDHDTG 581
Query: 6913 MIYWSDAKMDGIYRVRSTGGTPELVR--SDIASAAGVALHGQNMYWTDNRLEKLFRATSK 7086
IYW D +D I R+ GG ++VR S + G+ + G+++ W D L+K+F+A+ +
Sbjct: 582 YIYWVDDSLDLIARIHLDGGESQVVRYGSRYPTPYGITVFGESIIWVDRNLKKVFQASKQ 641
Query: 7087 PNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRASSPCQITDN---LRKSPCTQLCFATP 7257
P T P + + + DV +F + QP SP ++ +N C+ CFA P
Sbjct: 642 PGNTD---PPVVIRDKINLLRDVTIFDEHAQPL--SPAELNNNPCLQSNGGCSHFCFALP 696
Query: 7258 GTQTPTCSCARGVL--KGRTCE-EPDTYIMFSDGDKIIDVAIEPDVKASRPLKDPFPEIS 7428
TP C CA G L G++C + ++++S + + + +P R PF IS
Sbjct: 697 ELPTPRCGCAFGTLGNDGKSCATSQEDFLIYSLNNSLRSLHFDP-----RDHSLPFQVIS 751
Query: 7429 NLQT---FDVDVNLRRVYFVVE-SPVGVNISWFSMNNAENPRLVFGASKQPHAKEIRHIS 7596
T D D R++F + + + IS+ S+ + + V I
Sbjct: 752 VAGTAIALDYDRRNNRIFFTQKLNSLRGQISYVSLYSGSSSPTVL-------LSNIGVTD 804
Query: 7597 DMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTIASGDWTYALAIDPCSGLLFWSDSGYK 7776
+ DW+ ++IY++ + ++ G + + IA A+ +DPC G ++W+D G
Sbjct: 805 GIAFDWINRRIYYSDFSNQTINSMAEDGSNRAVIARVSKPRAIVLDPCRGYMYWTDWGTN 864
Query: 7777 TSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVDFRNQKIYWADVNRLNIEVADYDG 7956
+IER+ L G R IV+ S+ P +A+D +YWAD + IE + G
Sbjct: 865 A-------KIERATLGGNFRVPIVNTSLVWPNGLALDLETDLLYWADASLQKIERSTLTG 917
Query: 7957 QNRKVIAS-GYRAKSLDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVSDRRIPGALRVF 8133
NR+V+ S + + L ++ +++Y +D + ++R +K GS L V R+P +
Sbjct: 918 TNREVVVSTAFHSFGLTVYGQYIYWTDLYTRKIYRANKYDGSDL--VAMTTRLP--TQPS 973
Query: 8134 ASESDVRTRNQVCNALTSQLCKTDNGGCDQLCTVVADDIGLAASKVQCSCNDTYELVQEP 8313
+ V+T+ Q C S C NGGC +C G ++ QC + L +
Sbjct: 974 GISTVVKTQRQQC----SNPCDQFNGGCSHICAP-----GPNGAECQCPHEGNWYLANDN 1024
Query: 8314 GKDYPTQCVLRGSNSEPAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNT 8493
CV+ + C F C +G CI CD+ DC D SDE P C
Sbjct: 1025 -----KYCVV-----DTGTRC-NQLQFTCLNGHCINQDWKCDNDNDCGDGSDELPTVCAF 1073
Query: 8494 RSCPEDYNLCTNRRCIDSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTK 8673
+C C N RC+ +C++ +DCGD SDE C + F CSNG CI +
Sbjct: 1074 HTCRSTAFTCGNGRCVPYHYRCDYYNDCGDNSDEAGCLFRNCNSTTEFTCSNGRCIPLSY 1133
Query: 8674 VCDGHNDCHDEQVSDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADE 8853
VC+G N+CHD SDE CP P C +C TNIC+ A LCDG +DCGD +DE
Sbjct: 1134 VCNGINNCHDNDTSDEK--NCP--PHTCPPDFTKCQTTNICVPRAFLCDGDNDCGDGSDE 1189
Query: 8854 NQLFCMNQQCAQHYVRCPSG-RCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKI--CVG 9024
N ++C + C + +C S RCIP W CDG+ DC+DG DE DT G + C
Sbjct: 1190 NPIYCASHTCRSNEFQCLSPQRCIPSYWFCDGEADCADGSDEP-----DTCGHSVNTCRA 1244
Query: 9025 DYLFQCDNLKCISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYE 9204
FQCDN +CIS ++ RH C + C+ +F C ++ P
Sbjct: 1245 SQ-FQCDNGRCISGNWVCDGDNDCGDMSDEDQRHHCELQNCSSTQFTCVNSRP---PNRR 1300
Query: 9205 CIPRAWLCDGDVTCAGGEDESTELCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDG 9384
CIP+ W+CDGD C+ DE L + C+ GEF C+N C+ ++ CD NDC D
Sbjct: 1301 CIPQYWVCDGDADCSDALDE---LQNCTMRTCSAGEFSCANGRCVRQSFRCDRRNDCGDY 1357
Query: 9385 SDEHANCTYSSCQPDFFQCANHKCVPNSWKCDGNDDCEDGSDEKDCPKNSASAQKASKCS 9564
SDE C+Y C + F C N +C+P + CD ++DC DGSDE++ ++ C
Sbjct: 1358 SDERG-CSYPPCHANQFTCQNGRCIPRFFVCDEDNDCGDGSDEQEHLCHTPEPT----CP 1412
Query: 9565 NGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCMDMKIGYKC 9744
QF+C +G CI+ +VC+ DC+D SDE C I+EC + C+ C D + C
Sbjct: 1413 LHQFRCDNGHCIEMGRVCNHVDDCSDNSDEKG-CGINECLDSSISRCDHNCTDTITSFYC 1471
Query: 9745 DCFEGFAIDISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRT 9924
C G+ + +SD++SC +++EC E CSQKC++ +GSY C C GY D SC++
Sbjct: 1472 SCLPGYKL-MSDKRSCVDIDECKESPQLCSQKCENVVGSYICKCAPGYIREPDGKSCRQN 1530
Query: 9925 EMEPEPFFLLANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLR 10104
EP+ + +N++YIR ++ DG+ Y L QG NVV+LD D EK+ Y ID K + R
Sbjct: 1531 S-NIEPYLIFSNRYYIRNLTTDGSSYSLILQGLGNVVALDFDRVEKRLYWIDAEKQIIER 1589
Query: 10105 VDLDEMDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLI 10284
+ L++ ++ ET++ H + E +AVDWV RKLY L+ + V +L+GR K +
Sbjct: 1590 MFLNK-----TNRETIINHRLRRAESLAVDWVSRKLYWLDAILDCLFVSDLEGRHRKMIA 1644
Query: 10285 RDRI--------QQPKAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHD 10440
+ + + P+ IV+HP +G++++ +W + YIGRI +DG+ + +
Sbjct: 1645 QHCVDANNTFCFEHPRGIVLHPQRGHVYWADWGVHAYIGRIGMDGTNKSV-----IISTK 1699
Query: 10441 LGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWA 10620
+ WPNAI IDY +D L+W DAHL I F D +G+ R + H ++ +F+D ++W
Sbjct: 1700 IEWPNAITIDYTNDLLYWADAHLGYIEFSDLEGHHRHTVYDGSLPHPFALTIFEDTVFWT 1759
Query: 10621 DWNLREVLRCDKWTGKNETILKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIG 10800
DWN R V + +K+ G +L T P D+ + HP RQP NPCG NNGGCSHLCLI
Sbjct: 1760 DWNTRTVEKGNKYDGSGRVVLVNTTHKPFDIHVYHPYRQPISDNPCGTNNGGCSHLCLIK 1819
Query: 10801 AGGNGYTCSCPDQF--VLLSDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGS 10974
AGG G+TC+CPD F V L D+ C P C+ QF CG ++ KCIP W CDG+ DC DGS
Sbjct: 1820 AGGRGFTCACPDDFQTVQLRDRTLCMPMCSSTQFLCGNNE-KCIPIWWKCDGQKDCSDGS 1878
Query: 10975 DEPGESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXXEQN--CD-KACDPWMFK 11145
DEP +C R C +G+FQC + NCT P + E C+ C+ ++
Sbjct: 1879 DEP--DLCPHRFCRLGQFQCRDGNCTSPQALCNARQDCADGSDEDRVLCEHHRCESNEWQ 1936
Query: 11146 CAATGRCIPRRFTXXXXXXXXXRSDEADTLCMSAERNCTAEEFRCNNNKCIAKAWRXXXX 11325
C A RCIP+ + SDE + C A R C +F+CNN +CI ++W+
Sbjct: 1937 C-ANKRCIPQSWQCDSVNDCLDNSDEDTSHC--ASRTCRPGQFKCNNGRCIPQSWKCDVD 1993
Query: 11326 XXXXXXXXE-TPEC--AQIECKKGWT-RCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCP 11493
E EC A C C ++YRCIP WA CNG DDCRDNSDE
Sbjct: 1994 NDCGDYSDEPIDECTTAAYNCDNHTEFSCKTNYRCIPQWAVCNGFDDCRDNSDEQGCESV 2053
Query: 11494 TCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCI 11673
C G+FRCA + CIP RW CD +DCGDNSDE + R CSESEFRC D +CI
Sbjct: 2054 PCHPSGDFRCA-NHHCIPLRWKCDGTDDCGDNSDEENC----VPRECSESEFRCADQQCI 2108
Query: 11674 PGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHC 11853
P VCD C D DE C ++ C P H QC G C+ + CD + DC +A+DE C
Sbjct: 2109 PSRWVCDQENDCGDNSDERDCEMKTCHPEHFQCTSGHCVPKALACDGRADCLDASDESAC 2168
Query: 11854 ED--VSRRTCSPFEFECANSVCIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCA 12027
+ C FEC N VCI ++ SDE C + C+ P RFRC
Sbjct: 2169 PTRFPNGTYCPAAMFECKNHVCIQSFWICDGENDCVDGSDEEIHLCFNIPCESPQRFRCD 2228
Query: 12028 HSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSFSEYGDCSSDQFKCANGKCVNGTVACD 12207
+SR C+ QLCNG +DCG D SDE C + C+ ++KC+NG C++ CD
Sbjct: 2229 NSR-CVYGHQLCNGVDDCG--DGSDEKEEHCRK-PTHKPCTDTEYKCSNGNCISQHYVCD 2284
Query: 12208 RKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKHICTDVRD-GFYCHCRDGFRPDPQSPK 12384
+DCGD SDE GC+ +T E C+ CT + GF C CR GF+P
Sbjct: 2285 NVNDCGDLSDETGCNLGDNRTCAENI-----CEQNCTQLSSGGFICSCRPGFKPSTLDKN 2339
Query: 12385 ECIDIDECAGNNTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGA 12564
C DI+EC C Q C N+KGSY C C + +++ + + G+ C A G +++
Sbjct: 2340 SCQDINECEEFGICPQSCRNSKGSYECFCVDGFKS---MSTHYGERCAADGSPPLLLLPE 2396
Query: 12565 DDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXXXXPRK---ELMYW---IDGSE-RTIYR 12723
+ V++ + + + + P ++Y+ GS+ I R
Sbjct: 2397 N---VRIRKYNTSSEKFSEYLEEEEHIQTIDYDWDPEHIGLSVVYYTVLAQGSQFGAIKR 2453
Query: 12724 SAIANGNQSHEGQKLDVDFAAMGVV-PTAIAVDYTTGNLFIA-AVSENIENGLVTARKKR 12897
+ I N +VD ++ P +AVD+ +++ + A S+ IE
Sbjct: 2454 AYIPNFESGSNNPIREVDLGLKYLMQPDGLAVDWVGRHIYWSDAKSQRIE---------- 2503
Query: 12898 MSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECA 13077
V DGRY K ++ L QP A+ P G + ++D G KIE A
Sbjct: 2504 --------------VATLDGRYRKWLITTQLDQPAAIAVNPKLGLMFWTDQGKQPKIESA 2549
Query: 13078 DMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHI 13257
M+G HR ++V + + P ++ID +R+YW D K ++A+ DG++R ++++
Sbjct: 2550 WMNGEHRSVLVSENLGWPNGLSIDYLNDDRVYWSDSKEDVIEAIKYDGTDRRLIINEAMK 2609
Query: 13258 PYAVDVFENHIYWLSRESKTLYVQDKFGRGR------VSVLASDLEDGHTVRVSQKYAKD 13419
P+++D+FE+ +YW+++E ++ Q+KFG+ V+ + + H +R +Q
Sbjct: 2610 PFSLDIFEDKLYWVAKEKGEVWRQNKFGKENKEKVLVVNPWLTQVRIFHQLRYNQ----- 2664
Query: 13420 TQRTVSGCERAQCSHLCVSLPSTGFACLCPDG--IVPQLDGSCATQHVEALTMPKQCKCT 13593
+VS + CSHLC+ P G++C CP G V C +TMP C+C
Sbjct: 2665 ---SVSNPCKQVCSHLCLLRPG-GYSCACPQGSDFVTGSTVQCDAASELPVTMPPPCRCM 2720
Query: 13594 NGGKCRLDGS----CECTSDFEGDQCEKESSVSRKI-IGTLSENFIT------VXXXXXX 13740
+GG C D + C+C+S + G+ C E +SR I GT +T V
Sbjct: 2721 HGGNCYFDENELPKCKCSSGYSGEYC--EVGLSRGIPPGTTMAVLLTFVIVIIVGALVLV 2778
Query: 13741 XXXXXXXXXXXXXNLYKRRQL--LFKKNEAADG-------SVSFHGNVISFSNPVLENKQ 13893
L K L L K +E +G V+ V F + ++
Sbjct: 2779 GLFHYRKTGSLLPTLPKLPSLSSLAKPSENGNGVTFRSGADVNMDIGVSPFGPETIIDRS 2838
Query: 13894 DAPGSEFNMQQMTSMHDDSTTFTNPVYELEDVDMSSPPPSNDQPSTSASAMSPNRPSTSA 14073
A F M+ + F NP+Y +D +TS A++ PST A
Sbjct: 2839 MAMNEHFVME----VGKQPVIFENPMYAAKD-------------NTSKVALAVQGPSTGA 2881
Query: 14074 ASSFVPPTFDQDEIELKTADEIIVPKAEISKPPIPARP-------------KKEKADPLR 14214
+ VP + +E + I P +EI P PA P K++
Sbjct: 2882 QVT-VP-----ENVENQNYGRPIDP-SEIVPEPKPASPGADEIQGKKWNIFKRKPKQTTN 2934
Query: 14215 VDNPLY-DPDSEVSD 14256
+NP+Y + DSEV D
Sbjct: 2935 FENPIYAEMDSEVKD 2949
Score = 514 bits (1323), Expect = e-143
Identities = 407/1462 (27%), Positives = 644/1462 (43%), Gaps = 111/1462 (7%)
Frame = +1
Query: 1267 GEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLS---LKSLVYP------ 1419
G + D D + I+W D FS+ V I +IK + Y
Sbjct: 429 GRNVLHADVDVANGFIYWCD------FSSSVRSSNGIRRIKPDGSNFTNVVTYGIGANGI 482
Query: 1420 RCLAVDWITNTLYIIESG--SRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFT 1593
R +A+DW LY + I+V + R VLL + +P I +DP +F+
Sbjct: 483 RGVALDWAAGNLYFTNAFVYETLIEVLRINTTYRRVLLKVSVDMPRHIIVDPKHRYLFWA 542
Query: 1594 N---QLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGND 1764
+ + K+E + +D TNR LV+ G+ +D +YWVD +D + I G +
Sbjct: 543 DYGQKPKIERSFLDCTNRTVLVSEGIVTPRGLAMDHDTGYIYWVDDSLDLIARIHLDGGE 602
Query: 1765 RRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGI 1944
++V G P P+G+ +F + + W D V Q K +T + +
Sbjct: 603 SQVVRYGSRY-PTPYGITVFGESIIWVDRNLKKVFQASKQPGNTDPPVVIRDKINLLRDV 661
Query: 1945 SAYHPMAQP-GPGQSECLAMKIENPC--TNADCEGMCILSKDNGGFGVGYKCACPIGQKL 2115
+ + AQP P + NPC +N C C + +C C G
Sbjct: 662 TIFDEHAQPLSPAELN------NNPCLQSNGGCSHFCFALPELPT----PRCGCAFGTLG 711
Query: 2116 VNGKRCIDSI-DYLLFSSNKIVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVH 2292
+GK C S D+L++S N +R + + + +L V+ ++ G ++ D
Sbjct: 712 NDGKSCATSQEDFLIYSLNNSLRSLHFDPRDHSLPFQVISVA-------GTAIALDYDRR 764
Query: 2293 GNSFFYADIMDNTIYRIRP----DGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDNIRNS 2460
N F+ +++ +I G + VL+++ ++FDWI++++YY D +
Sbjct: 765 NNRIFFTQKLNSLRGQISYVSLYSGSSSPTVLLSNIGVTDGIAFDWINRRIYYSDFSNQT 824
Query: 2461 LEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQ 2640
+ + E G R +I + P ++V+ P +G +++ + A I R + G
Sbjct: 825 IN--SMAEDGS-------NRAVIARVSKPRAIVLDPCRGYMYWTDWGTNAKIERATLGGN 875
Query: 2641 NCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVKLDIDNPIPVAITI 2820
I NT+L P+ +A+D + L W D L+ I G N + +T+
Sbjct: 876 FRVPIVNTSLVWPNGLALDLETDLLYWADASLQKIERSTLTGTNREVVVSTAFHSFGLTV 935
Query: 2821 MNEYIYYVHQRPYSIRRVHKKNG---------------GGSKIV---REFGADERSIFSL 2946
+YIY+ I R +K +G G S +V R+ ++ F+
Sbjct: 936 YGQYIYWTDLYTRKIYRANKYDGSDLVAMTTRLPTQPSGISTVVKTQRQQCSNPCDQFN- 994
Query: 2947 KACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKC-----ACRQGFMINKE 3111
CSH P P+ + C+ A ++ + +C C G IN++
Sbjct: 995 GGCSHICAPGPNGAE---CQCPHEGNWYLANDNKYCVVDTGTRCNQLQFTCLNGHCINQD 1051
Query: 3112 ----NNHSCQKDPAEKIEQLCSSN---STQFQCKNGRCIPKEWKCDGENDCLDESDEIDE 3270
N++ C D ++++ +C+ + ST F C NGRC+P ++CD NDC D SDE
Sbjct: 1052 WKCDNDNDCG-DGSDELPTVCAFHTCRSTAFTCGNGRCVPYHYRCDYYNDCGDNSDEAGC 1110
Query: 3271 KGDKCFHETE------------------------------------CAENTIKCRNTKKC 3342
C TE C + KC+ T C
Sbjct: 1111 LFRNCNSTTEFTCSNGRCIPLSYVCNGINNCHDNDTSDEKNCPPHTCPPDFTKCQTTNIC 1170
Query: 3343 IPAQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQC-DNHRCIPEQWKXXXXXXXXX 3519
+P YC C + +FQC RCIP W
Sbjct: 1171 VPRAFLCDGDNDCGDGSDENPIYCASH---TCRSNEFQCLSPQRCIPSYWFCDGEADCAD 1227
Query: 3520 XXXEKLEMCGNA--TCAANQFSCANGRCIPIYWLCDGDNDCYDGTDED-KERCPPVQCSA 3690
E + CG++ TC A+QF C NGRCI W+CDGDNDC D +DED + C CS+
Sbjct: 1228 GSDEP-DTCGHSVNTCRASQFQCDNGRCISGNWVCDGDNDCGDMSDEDQRHHCELQNCSS 1286
Query: 3691 LQFRCANGR----QCVPLRNHXXXXXXXXXXXXXXXXAVTAESCTPDQFKCVSSGLCIPA 3858
QF C N R +C+P + T +C+ +F C ++G C+
Sbjct: 1287 TQFTCVNSRPPNRRCIP-QYWVCDGDADCSDALDELQNCTMRTCSAGEFSC-ANGRCVRQ 1344
Query: 3859 SWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKCGNGRCILNNWLCDGENDCGDGSDESS 4038
S++ SDE GC S C ++QF C NGRCI ++CD +NDCGDGSDE
Sbjct: 1345 SFRCDRRNDCGDYSDER--GC-SYPPCHANQFTCQNGRCIPRFFVCDEDNDCGDGSDEQ- 1400
Query: 4039 ERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRA 4218
E C T CP C+N CI + ++C+ C +DE G + + +
Sbjct: 1401 EHLCHTPEPT--CPLHQFRCDNGH--CIEMGRVCNHVDDCSDNSDEKGCGINECLDSSIS 1456
Query: 4219 GCSFKCHNSPNGPICSCPFGEQLVN-KTKCEPENECLDSSS-CSQRCKDEKHGFTCSCDE 4392
C C ++ CSC G +L++ K C +EC +S CSQ+C++ + C C
Sbjct: 1457 RCDHNCTDTITSFYCSCLPGYKLMSDKRSCVDIDECKESPQLCSQKCENVVGSYICKCAP 1516
Query: 4393 GYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGAIVE---NAIALAWDS 4563
GY + D ++C+ N++ I+ SNR YY + + ++ I++ N +AL +D
Sbjct: 1517 GYIREPDGKSCRQNSNIEPYLIF-SNR---YYIRNLTTDGSSYSLILQGLGNVVALDFDR 1572
Query: 4564 LTDRIYWSDIREKKILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVDSSLNTIEV 4743
+ R+YW D ++ I N TN I L E +A+DWV R LYW+D+ L+ + V
Sbjct: 1573 VEKRLYWIDAEKQIIERMFLNKTNRETIINHRLRRAESLAVDWVSRKLYWLDAILDCLFV 1632
Query: 4744 ANLEDPKQRTLLVH----QNV---SQPRGIAVDPRKGVMFWTDWGQNPCIERASMDGTDR 4902
++LE ++ + H N PRGI + P++G ++W DWG + I R MDGT++
Sbjct: 1633 SDLEGRHRKMIAQHCVDANNTFCFEHPRGIVLHPQRGHVYWADWGVHAYIGRIGMDGTNK 1692
Query: 4903 QIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALA 5082
+I+ TKI WPN I +DYT D +Y+AD+ L +I+F + +G R V S + HP AL
Sbjct: 1693 SVIISTKIEWPNAITIDYTNDLLYWADAHLGYIEFSDLEGHHRHTVYDGS--LPHPFALT 1750
Query: 5083 IFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTN 5262
IFED ++++D + ++ KY +G+ +T K + HP QP I +NPC TN
Sbjct: 1751 IFEDTVFWTDWNTRTVEKGNKY-DGSGRVVLVNTTHKPFDIHVYHPYRQP-ISDNPCGTN 1808
Query: 5263 --PCSHLCLLN-NKNTFTCKCP 5319
CSHLCL+ FTC CP
Sbjct: 1809 NGGCSHLCLIKAGGRGFTCACP 1830
Score = 338 bits (866), Expect = 3e-90
Identities = 327/1256 (26%), Positives = 504/1256 (40%), Gaps = 175/1256 (13%)
Frame = +1
Query: 2083 YKCACPIGQ-KLVNGKRCIDSID---YLLFSSNKIVRGIFPEINEKALAEAVLPISPISQ 2250
Y C C G + +GK C + + YL+FS+ +R + + + +L
Sbjct: 1510 YICKCAPGYIREPDGKSCRQNSNIEPYLIFSNRYYIRNLTTDGSSYSLI----------L 1559
Query: 2251 RRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWISKQ 2430
+ +G ++ D ++ D I R+ + ++ S++ DW+S++
Sbjct: 1560 QGLGNVVALDFDRVEKRLYWIDAEKQIIERMFLNKTNRETIINHRLRRAESLAVDWVSRK 1619
Query: 2431 LYYVDNIRNSLEVVKI-GETGLVHPDELVRRQLITELRDPVSVVVHPWKGLLFYAEAMRP 2607
LY++D I + L V + G + V P +V+HP +G +++A+
Sbjct: 1620 LYWLDAILDCLFVSDLEGRHRKMIAQHCVDANNTFCFEHPRGIVLHPQRGHVYWADWGVH 1679
Query: 2608 AAIYRCHIDGQNCQVIRNTTL--------------------------------------- 2670
A I R +DG N VI +T +
Sbjct: 1680 AYIGRIGMDGTNKSVIISTKIEWPNAITIDYTNDLLYWADAHLGYIEFSDLEGHHRHTVY 1739
Query: 2671 --GRPSEMAIDFAENRLCWGDTLLKTISCMD-FDGKNVVKLDIDNPIPVAITIMNEYIYY 2841
P A+ E+ + W D +T+ + +DG V L P I ++Y+
Sbjct: 1740 DGSLPHPFALTIFEDTVFWTDWNTRTVEKGNKYDGSGRVVLVNTTHKPFDI-----HVYH 1794
Query: 2842 VHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCR-ASQC 3018
+++P S NGG S + A R AC PDD + R + C
Sbjct: 1795 PYRQPISDNPCGTNNGGCSHLCL-IKAGGRGFTC--AC-------PDDFQTVQLRDRTLC 1844
Query: 3019 TQLCFATPSESHPNE----LEAKC--------------------------ACRQGFMINK 3108
+C +T NE + KC CR G +
Sbjct: 1845 MPMCSSTQFLCGNNEKCIPIWWKCDGQKDCSDGSDEPDLCPHRFCRLGQFQCRDGNCTSP 1904
Query: 3109 ENNHSCQKDPAEKIEQ---LCSSN---STQFQCKNGRCIPKEWKCDGENDCLDESDEIDE 3270
+ + ++D A+ ++ LC + S ++QC N RCIP+ W+CD NDCLD SDE
Sbjct: 1905 QALCNARQDCADGSDEDRVLCEHHRCESNEWQCANKRCIPQSWQCDSVNDCLDNSDE--- 1961
Query: 3271 KGDKCFHETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKD-GQKPV--CA 3441
C T C KC N + CIP C D +P+ C
Sbjct: 1962 DTSHCASRT-CRPGQFKCNNGR-CIPQSWKCDVDND-----------CGDYSDEPIDECT 2008
Query: 3442 AKKFQCDNH---------RCIPEQWKXXXXXXXXXXXXEKLEMCGNATC-AANQFSCANG 3591
+ CDNH RCIP QW ++ + C + C + F CAN
Sbjct: 2009 TAAYNCDNHTEFSCKTNYRCIP-QWAVCNGFDDCRDNSDE-QGCESVPCHPSGDFRCANH 2066
Query: 3592 RCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQCVPLRNHXXXXXXXXXX 3771
CIP+ W CDG +DC D +DE E C P +CS +FRCA+ +QC+P R
Sbjct: 2067 HCIPLRWKCDGTDDCGDNSDE--ENCVPRECSESEFRCAD-QQCIPSR--WVCDQENDCG 2121
Query: 3772 XXXXXXAVTAESCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCT--SGRQCSS 3945
++C P+ F+C +SG C+P + SDE +G C +
Sbjct: 2122 DNSDERDCEMKTCHPEHFQC-TSGHCVPKALACDGRADCLDASDESACPTRFPNGTYCPA 2180
Query: 3946 DQFKCGNGRCILNNWLCDGENDC------------------------------------- 4014
F+C N CI + W+CDGENDC
Sbjct: 2181 AMFECKNHVCIQSFWICDGENDCVDGSDEEIHLCFNIPCESPQRFRCDNSRCVYGHQLCN 2240
Query: 4015 -----GDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEG 4179
GDGSDE E C+ + + C C N CI H +CD C +DE
Sbjct: 2241 GVDDCGDGSDEKEEH-CRKPTH-KPCTDTEYKCSNG--NCISQHYVCDNVNDCGDLSDET 2296
Query: 4180 G-------RCARDLCSADRAGCSFKCHNSPNGPICSC--PFGEQLVNKTKCEPENECLDS 4332
G CA ++C + C+ S G ICSC F ++K C+ NEC +
Sbjct: 2297 GCNLGDNRTCAENICEQN---CT---QLSSGGFICSCRPGFKPSTLDKNSCQDINECEEF 2350
Query: 4333 SSCSQRCKDEKHGFTCSCDEGYE--------------------LDVDKRTCKVADNVKDT 4452
C Q C++ K + C C +G++ L + R K + +
Sbjct: 2351 GICPQSCRNSKGSYECFCVDGFKSMSTHYGERCAADGSPPLLLLPENVRIRKYNTSSEKF 2410
Query: 4453 RIYVSNRNRIYYSDHKLDNWHTFGAIVENAIALAWDSLTDRIYWSDIREKKILSANRNGT 4632
Y+ I D+ D H ++V + L + I+ I +
Sbjct: 2411 SEYLEEEEHIQTIDYDWDPEHIGLSVVYYTV------LAQGSQFGAIKRAYIPNFESGSN 2464
Query: 4633 NATVFIADGLDI---TEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQP 4803
N + GL +G+A+DWVGR++YW D+ IEVA L D + R L+ + QP
Sbjct: 2465 NPIREVDLGLKYLMQPDGLAVDWVGRHIYWSDAKSQRIEVATL-DGRYRKWLITTQLDQP 2523
Query: 4804 RGIAVDPRKGVMFWTDWGQNPCIERASMDGTDRQIIVKTKIYWPNTIALDY-TTDRVYFA 4980
IAV+P+ G+MFWTD G+ P IE A M+G R ++V + WPN +++DY DRVY++
Sbjct: 2524 AAIAVNPKLGLMFWTDQGKQPKIESAWMNGEHRSVLVSENLGWPNGLSIDYLNDDRVYWS 2583
Query: 4981 DSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGT 5160
DSK D I+ + YDG+ R ++ + P +L IFED +Y+ + +K +V+ + G
Sbjct: 2584 DSKEDVIEAIKYDGTDRRLIINEA---MKPFSLDIFEDKLYWVAK--EKGEVWRQNKFGK 2638
Query: 5161 TSEYPSHTFSKALGVVAV-HPVLQPVIKNNPCSTNPCSHLCLLNNKNTFTCKCPMG 5325
++ + L V + H + +NPC CSHLCLL ++C CP G
Sbjct: 2639 ENKEKVLVVNPWLTQVRIFHQLRYNQSVSNPCK-QVCSHLCLL-RPGGYSCACPQG 2692
Score = 290 bits (743), Expect = 5e-76
Identities = 214/684 (31%), Positives = 303/684 (44%), Gaps = 32/684 (4%)
Frame = +1
Query: 169 DFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAEYQRC 348
DFRC + CI W C +++C CI C
Sbjct: 2060 DFRCANHHCIPLRWKCDGTDDCGDNSDEENCVPRECSESEFRCADQ-----QCIPSRWVC 2114
Query: 349 DNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCS 528
D DC D SDE+DC T C ++ F C G C + CDG+ DC D SDE +
Sbjct: 2115 DQENDCGDNSDERDCEMKT--CHPEH-FQCTSGH-CVPKALACDGRADCLDASDESACPT 2170
Query: 529 R--NHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEP-DTCEFKKCTANE-FQCKN 696
R N T C F C + CIQ W+CDG DC DGSDE C C + + F+C N
Sbjct: 2171 RFPNGTYCPAAMFECKNHV-CIQSFWICDGENDCVDGSDEEIHLCFNIPCESPQRFRCDN 2229
Query: 697 KRCQPRKFRCDYYDDCGDNSDEDE--CGEYR---CPPGKWNCPGTGHCIDQLKLCDGSKD 861
RC C+ DDCGD SDE E C + C ++ C G+CI Q +CD D
Sbjct: 2230 SRCVYGHQLCNGVDDCGDGSDEKEEHCRKPTHKPCTDTEYKC-SNGNCISQHYVCDNVND 2288
Query: 862 CADGADEQQCS---QNLCPSLGCQAGCHPSPHGGE-CTCPSGYKLDDRFHRTCSDINECA 1029
C D +DE C+ C C+ C GG C+C G+K +C DINEC
Sbjct: 2289 CGDLSDETGCNLGDNRTCAENICEQNCTQLSSGGFICSCRPGFKPSTLDKNSCQDINECE 2348
Query: 1030 EFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARRE 1209
EFG C Q C N + + C C+ ++ +G C ++ + + L
Sbjct: 2349 EFGICPQSCRNSKGSYECFCVDGFKSMSTHYGER---------CAADGSPPLLLLPEN-- 2397
Query: 1210 GLYRLNPKNPDEEV--KKLASGEFIYGIDFDY-----GDRKIFWTDRLAHSAFSADVD-- 1362
R+ N E + L E I ID+D+ G +++T S F A
Sbjct: 2398 --VRIRKYNTSSEKFSEYLEEEEHIQTIDYDWDPEHIGLSVVYYTVLAQGSQFGAIKRAY 2455
Query: 1363 ----DEGEISQIKK--LSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVL 1524
+ G + I++ L LK L+ P LAVDW+ +Y ++ S+RI+V++ DG R L
Sbjct: 2456 IPNFESGSNNPIREVDLGLKYLMQPDGLAVDWVGRHIYWSDAKSQRIEVATLDGRYRKWL 2515
Query: 1525 LADGLTLPLDIALDPLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHTHQVSGIVVD-I 1692
+ L P IA++P G MF+T+ Q K+E+A M+G +R LV+ + +G+ +D +
Sbjct: 2516 ITTQLDQPAAIAVNPKLGLMFWTDQGKQPKIESAWMNGEHRSVLVSENLGWPNGLSIDYL 2575
Query: 1693 TAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQ 1872
RVYW D K D +E+I Y G DRR++ +N PF L +F+ LYW + V +
Sbjct: 2576 NDDRVYWSDSKEDVIEAIKYDGTDRRLI---INEAMKPFSLDIFEDKLYWVAKEKGEVWR 2632
Query: 1873 VEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCIL 2052
KFG + K N + + +H + + NPC C +C+L
Sbjct: 2633 QNKFGKENK--EKVLVVNPWLTQVRIFHQLR---------YNQSVSNPCKQV-CSHLCLL 2680
Query: 2053 SKDNGGFGVGYKCACPIGQKLVNG 2124
GY CACP G V G
Sbjct: 2681 RPG------GYSCACPQGSDFVTG 2698
Score = 286 bits (733), Expect = 8e-75
Identities = 265/1044 (25%), Positives = 447/1044 (42%), Gaps = 39/1044 (3%)
Frame = +1
Query: 4270 PFGEQLVNKTKCEPENECLDSSSCSQRC----KDEKHGFTCSCDEGYELDVDKRTCKVAD 4437
P G ++ ++ P S+SCS C + +H ++C+C G+ L D C D
Sbjct: 21 PLGITAIHPSRQPPSRNPCASASCSHLCLLSAQAPRH-YSCACPSGWNLSDDSVNCVRGD 79
Query: 4438 NVKDTRIYVSNRNRIYYS---DHKLDNWHTFGAI--VENAIALAWDSLTDRIYWSDIREK 4602
+S R+ I + D ++ + I +++ + +D IYW +
Sbjct: 80 QP----FLMSVRDNIIFGISLDPEVKSNDAMVPISGIQHGYDVEFDDSEQFIYWVE-NPG 134
Query: 4603 KILSANRNGTNATVFIADGL-DITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQ--RT 4773
+I +G+N TVF L + G+ALDWV RN+Y+ + +IEV L+ + +T
Sbjct: 135 EIHRVKTDGSNRTVFAPLSLLGSSLGLALDWVSRNIYYTTPASRSIEVLTLKGDTRYGKT 194
Query: 4774 LLVHQ----NVSQPRGIAVDPRKGVMFWTDWGQN----PCIERASMDGTDRQIIVKTKIY 4929
L+ + V P GIAVDP +G ++W+D G + I A+MDGT +I+ +
Sbjct: 195 LIANDGTPLGVGFPVGIAVDPARGKLYWSDHGTDSGVPAKIASANMDGTSLKILFTGNLQ 254
Query: 4930 WPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFEDMMYYS 5109
+ LD ++Y+A + I+ N DG+ R ++ + HP L ++ +YYS
Sbjct: 255 HLEVVTLDIQEQKLYWAVTSRGVIERGNVDGTERMILV---HHLAHPWGLVVYGSFLYYS 311
Query: 5110 DRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTNP--CSHLCL 5283
D + + ++ K +G G+ H +N CS NP C +CL
Sbjct: 312 DEQYEVIERVDK-SSGNNKVVLRDNVPYLRGLRVYHR-RNAADSSNGCSNNPNACQQICL 369
Query: 5284 LNNKNTFTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNVFGIEMNSASEKETPVLAGMV 5463
F+C C G KL G+ C F+V+ V G + + E MV
Sbjct: 370 PVPGGMFSCACASGFKLSPDGRSC-SPYNSFMVVSMLPAVRGFSLELSDHSE-----AMV 423
Query: 5464 PLSGLG-NAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNGGNKTKMFSSAV 5640
P++G G N A D + ++ + + + + + + I R +G N T + + +
Sbjct: 424 PVAGQGRNVLHADVDVANGFIYWCDFS------SSVRSSNGIRRIKPDGSNFTNVVTYGI 477
Query: 5641 -PDDAYCLGFDWNGRNLVVGNKIT--QTIEIIRTQGKQYRSVILSNDQSXXXXXXXXXXX 5811
+ + DW NL N IE++R YR V+L
Sbjct: 478 GANGIRGVALDWAAGNLYFTNAFVYETLIEVLRI-NTTYRRVLLK-----VSVDMPRHII 531
Query: 5812 XXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAIDTTNTRVYFSEA 5991
Y+FW D G K+ R+ LD +N V+ S + +A+D +Y+ +
Sbjct: 532 VDPKHRYLFWADYG---QKPKIERSFLDCTNRTVLVSEGIVTPRGLAMDHDTGYIYWVDD 588
Query: 5992 KAGRISSVTYDGQDRHYVLSDGGRQPN--GLAFYGDRLFYADSAFDSI-EVATINGDSQP 6162
I+ + DG + V+ G R P G+ +G+ + + D + + + G++ P
Sbjct: 589 SLDLIARIHLDGGESQ-VVRYGSRYPTPYGITVFGESIIWVDRNLKKVFQASKQPGNTDP 647
Query: 6163 PQWTHFK----KDVENL-ANIKALQPRASSSGHPCHINNGNCDHICIPL-MFAQRTCTCA 6324
P K +DV + + L P A + +PC +NG C H C L C CA
Sbjct: 648 PVVIRDKINLLRDVTIFDEHAQPLSP-AELNNNPCLQSNGGCSHFCFALPELPTPRCGCA 706
Query: 6325 NGYVKDGQTSCKLFDESFVIVATKTKVIGYPID-ETQSKGVAMEPIGGLSITGVDYDYES 6501
G + + SC E F+I + + D S + + G +I +DYD +
Sbjct: 707 FGTLGNDGKSCATSQEDFLIYSLNNSLRSLHFDPRDHSLPFQVISVAGTAI-ALDYDRRN 765
Query: 6502 KTIYVAEASGINKGITAYT---IGESSPRAVIRDSIGSLTIKSLAIDWINYNMYFINHDA 6672
I+ + +G +Y G SSP V+ +IG +A DWIN +Y+ D
Sbjct: 766 NRIFFTQKLNSLRGQISYVSLYSGSSSP-TVLLSNIG--VTDGIAFDWINRRIYY--SDF 820
Query: 6673 ERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQRSFLDGSRRE 6852
I DG+ R ++ + P +I +DP Y+YW D G I+R+ L G+ R
Sbjct: 821 SNQTINSMAEDGSNRAVI--ARVSKPRAIVLDPCRGYMYWTDWGTNAKIERATLGGNFRV 878
Query: 6853 VIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPELVRSDIASAAGVALHGQ 7032
IV++ + P L +D+ + ++YW+DA + I R TG E+V S + G+ ++GQ
Sbjct: 879 PIVNTSLVWPNGLALDLETDLLYWADASLQKIERSTLTGTNREVVVSTAFHSFGLTVYGQ 938
Query: 7033 NMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRASSPCQITD 7212
+YWTD K++RA +K + + L+ T + I V + + S+PC
Sbjct: 939 YIYWTDLYTRKIYRA-NKYDGSDLVAMTTRLPTQPSGISTVV---KTQRQQCSNPC---- 990
Query: 7213 NLRKSPCTQLCFATPGTQTPTCSC 7284
+ C+ +C PG C C
Sbjct: 991 DQFNGGCSHIC--APGPNGAECQC 1012
Score = 280 bits (716), Expect = 7e-73
Identities = 194/682 (28%), Positives = 289/682 (41%), Gaps = 73/682 (10%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQ 453
C+S+++QC + CI Y CD DCADGSDE D +V+ + F C +GR
Sbjct: 1199 CRSNEFQCLS----PQRCIPSYWFCDGEADCADGSDEPDTCGHSVNTCRASQFQCDNGR- 1253
Query: 454 CFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKT----QCIQKSWVCDGSKD 621
C + CDG DC D+SDE C QF C + +CI + WVCDG D
Sbjct: 1254 CISGNWVCDGDNDCGDMSDEDQRHHCELQNCSSTQFTCVNSRPPNRRCIPQYWVCDGDAD 1313
Query: 622 CADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKW 801
C+D DE C + C+A EF C N RC + FRCD +DCGD SDE C C ++
Sbjct: 1314 CSDALDELQNCTMRTCSAGEFSCANGRCVRQSFRCDRRNDCGDYSDERGCSYPPCHANQF 1373
Query: 802 NCPGTGHCIDQLKLCDGSKDCADGADEQQ----------------CSQNLCPSLG----- 918
C G CI + +CD DC DG+DEQ+ C C +G
Sbjct: 1374 TCQN-GRCIPRFFVCDEDNDCGDGSDEQEHLCHTPEPTCPLHQFRCDNGHCIEMGRVCNH 1432
Query: 919 -------------------------CQAGCHPSPHGGECTCPSGYKL-DDRFHRTCSDIN 1020
C C + C+C GYKL D+ R+C DI+
Sbjct: 1433 VDDCSDNSDEKGCGINECLDSSISRCDHNCTDTITSFYCSCLPGYKLMSDK--RSCVDID 1490
Query: 1021 ECAEFGY-CDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFV 1197
EC E C Q C N + C C PG C N+ + L
Sbjct: 1491 ECKESPQLCSQKCENVVGSYICKC-----------APGYIREPDGKSCRQNSNIEPYLIF 1539
Query: 1198 ARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEI 1377
+ R + L + G + +DFD +++++W +D E +I
Sbjct: 1540 SNRYYIRNLTTDGSSYSLILQGLGNVV-ALDFDRVEKRLYW------------IDAEKQI 1586
Query: 1378 SQ---IKKLSLKSLVYPRC-----LAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLAD 1533
+ + K + ++++ R LAVDW++ LY +++ + VS +G R ++
Sbjct: 1587 IERMFLNKTNRETIINHRLRRAESLAVDWVSRKLYWLDAILDCLFVSDLEGRHRKMIAQH 1646
Query: 1534 GLTL--------PLDIALDPLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHTHQVSGI 1680
+ P I L P RG +++ + + MDGTN+ +++T + I
Sbjct: 1647 CVDANNTFCFEHPRGIVLHPQRGHVYWADWGVHAYIGRIGMDGTNKSVIISTKIEWPNAI 1706
Query: 1681 VVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRL 1860
+D T +YW D + +E D +G+ R V G +PHPF L +F+ ++WTDW
Sbjct: 1707 TIDYTNDLLYWADAHLGYIEFSDLEGHHRHTVYDGS--LPHPFALTIFEDTVFWTDWNTR 1764
Query: 1861 GVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPC--TNADC 2034
V + K+ +++ NT + P I YHP QP +NPC N C
Sbjct: 1765 TVEKGNKYDGSGRVVLVNTTHK--PFDIHVYHPYRQP----------ISDNPCGTNNGGC 1812
Query: 2035 EGMCILSKDNGGFGVGYKCACP 2100
+C++ G G+ CACP
Sbjct: 1813 SHLCLIKAG----GRGFTCACP 1830
Score = 177 bits (450), Expect = 5e-42
Identities = 108/309 (34%), Positives = 142/309 (45%), Gaps = 13/309 (4%)
Frame = +1
Query: 145 ASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVS 324
AS C F+CN+G+CI W P C + + CD +T S
Sbjct: 1967 ASRTCRPGQFKCNNGRCIPQSW---KCDVDNDCGDYSDEPIDECTTAAYNCDNHTEFSCK 2023
Query: 325 ----CIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYD 492
CI ++ C+ DC D SDE+ C +V C F CA+ C + KCDG D
Sbjct: 2024 TNYRCIPQWAVCNGFDDCRDNSDEQGC--ESVPCHPSGDFRCAN-HHCIPLRWKCDGTDD 2080
Query: 493 CRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCT 672
C D SDE++ R C + +FRCAD+ QCI WVCD DC D SDE D CE K C
Sbjct: 2081 CGDNSDEENCVPRE---CSESEFRCADQ-QCIPSRWVCDQENDCGDNSDERD-CEMKTCH 2135
Query: 673 ANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDEC------GEYRCPPGKWNCPGTGHCIDQ 834
FQC + C P+ CD DC D SDE C G Y CP + C CI
Sbjct: 2136 PEHFQCTSGHCVPKALACDGRADCLDASDESACPTRFPNGTY-CPAAMFECK-NHVCIQS 2193
Query: 835 LKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGEC---TCPSGYKLDDRFHRT 1005
+CDG DC DG+DE+ +LC ++ C+ SP C C G H+
Sbjct: 2194 FWICDGENDCVDGSDEE---IHLCFNIPCE-----SPQRFRCDNSRCVYG-------HQL 2238
Query: 1006 CSDINECAE 1032
C+ +++C +
Sbjct: 2239 CNGVDDCGD 2247
Score = 165 bits (418), Expect = 3e-38
Identities = 163/652 (25%), Positives = 291/652 (44%), Gaps = 43/652 (6%)
Frame = +1
Query: 1279 YGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRC--------LAV 1434
Y ++FD ++ I+W V++ GEI ++K V+ LA+
Sbjct: 116 YDVEFDDSEQFIYW------------VENPGEIHRVKTDGSNRTVFAPLSLLGSSLGLAL 163
Query: 1435 DWITNTLYIIESGSRRIDVSSYDGERR---TVLLADGLTL----PLDIALDPLRGEMFFT 1593
DW++ +Y SR I+V + G+ R T++ DG L P+ IA+DP RG+++++
Sbjct: 164 DWVSRNIYYTTPASRSIEVLTLKGDTRYGKTLIANDGTPLGVGFPVGIAVDPARGKLYWS 223
Query: 1594 NQ-------LKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDY 1752
+ K+ +A MDGT+ + L + + + +DI +++YW +E +
Sbjct: 224 DHGTDSGVPAKIASANMDGTSLKILFTGNLQHLEVVTLDIQEQKLYWAVTSRGVIERGNV 283
Query: 1753 QGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVF 1932
G +R I+ ++ + HP+GL ++ +LY++D + +V+K + K++ +N +
Sbjct: 284 DGTERMIL---VHHLAHPWGLVVYGSFLYYSDEQYEVIERVDKSSGNNKVVL--RDNVPY 338
Query: 1933 PMGISAYHPMAQPGPGQSECLAMKIENPCTNAD--CEGMCILSKDNGGFGVGYKCACPIG 2106
G+ YH A N C+N C+ +C+ GG + CAC G
Sbjct: 339 LRGLRVYHRRN----------AADSSNGCSNNPNACQQICL--PVPGGM---FSCACASG 383
Query: 2107 QKL-VNGKRCIDSIDYLLFSSNKIVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVEC 2283
KL +G+ C +++ S VRG E+++ +EA++P++ Q R ++ +V
Sbjct: 384 FKLSPDGRSCSPYNSFMVVSMLPAVRGFSLELSDH--SEAMVPVA--GQGRNVLHADV-- 437
Query: 2284 DVHGNSFFYADI-----MDNTIYRIRPDGEGAAPVLVTHN---DGLFSMSFDWISKQLYY 2439
DV ++ D N I RI+PDG V VT+ +G+ ++ DW + LY+
Sbjct: 438 DVANGFIYWCDFSSSVRSSNGIRRIKPDGSNFTNV-VTYGIGANGIRGVALDWAAGNLYF 496
Query: 2440 VDNI--RNSLEVVKIGETGLVHPDELVRRQLITELRD-PVSVVVHPWKGLLFYAEAMRPA 2610
+ +EV++I T RR L+ D P ++V P LF+A+ +
Sbjct: 497 TNAFVYETLIEVLRINTT--------YRRVLLKVSVDMPRHIIVDPKHRYLFWADYGQKP 548
Query: 2611 AIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDG--KNVVKL 2784
I R +D N V+ + + P +A+D + W D L I+ + DG VV+
Sbjct: 549 KIERSFLDCTNRTVLVSEGIVTPRGLAMDHDTGYIYWVDDSLDLIARIHLDGGESQVVRY 608
Query: 2785 DIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSK--IVREFGADERSIFSLKACS 2958
P P IT+ E I +V + + + K+ G ++R+ + +
Sbjct: 609 GSRYPTPYGITVFGESIIWVDRNLKKVFQASKQPGNTDPPVVIRD---KINLLRDVTIFD 665
Query: 2959 HQNQPI-PDDSREHPCRASQ--CTQLCFATPSESHPNELEAKCACRQGFMIN 3105
QP+ P + +PC S C+ CFA P P +C C G + N
Sbjct: 666 EHAQPLSPAELNNNPCLQSNGGCSHFCFALPELPTP-----RCGCAFGTLGN 712
Score = 163 bits (413), Expect = 1e-37
Identities = 116/386 (30%), Positives = 151/386 (39%), Gaps = 77/386 (19%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAE 336
CN+ F C +G CI +W C + +T + C+
Sbjct: 1035 CNQLQFTCLNGHCINQDWKCDNDNDCGDGSDELPTV---CAFHTCRSTAFTCGNGRCVPY 1091
Query: 337 YQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGR------------QCFDVSKK-- 474
+ RCD DC D SDE C +C+S F C++GR C D
Sbjct: 1092 HYRCDYYNDCGDNSDEAGCLFR--NCNSTTEFTCSNGRCIPLSYVCNGINNCHDNDTSDE 1149
Query: 475 ---------------------------CDGKYDCRDLSDEKDSCSRNHTACFQYQFRCAD 573
CDG DC D SDE +HT C +F+C
Sbjct: 1150 KNCPPHTCPPDFTKCQTTNICVPRAFLCDGDNDCGDGSDENPIYCASHT-CRSNEFQCLS 1208
Query: 574 KTQCIQKSWVCDGSKDCADGSDEPDTC--EFKKCTANEFQCKNKRCQPRKFRCDYYDDCG 747
+CI W CDG DCADGSDEPDTC C A++FQC N RC + CD +DCG
Sbjct: 1209 PQRCIPSYWFCDGEADCADGSDEPDTCGHSVNTCRASQFQCDNGRCISGNWVCDGDNDCG 1268
Query: 748 DNSDEDE---CGEYRCPPGKWNC----PGTGHCIDQLKLCDGSKDCADGADEQQ------ 888
D SDED+ C C ++ C P CI Q +CDG DC+D DE Q
Sbjct: 1269 DMSDEDQRHHCELQNCSSTQFTCVNSRPPNRRCIPQYWVCDGDADCSDALDELQNCTMRT 1328
Query: 889 CS--------------------QNLCPSLGCQAGC-HPSPHGGECTCPSGYKLDDRFHRT 1005
CS +N C + GC +P H + TC +G + F
Sbjct: 1329 CSAGEFSCANGRCVRQSFRCDRRNDCGDYSDERGCSYPPCHANQFTCQNGRCIPRFF--V 1386
Query: 1006 CSDINECAEFGYCDQLCANHRPGFTC 1083
C + N+C + G +Q H P TC
Sbjct: 1387 CDEDNDCGD-GSDEQEHLCHTPEPTC 1411
Score = 157 bits (398), Expect = 5e-36
Identities = 86/262 (32%), Positives = 125/262 (46%), Gaps = 5/262 (1%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPG--CKSDQWQCDTYTWHSVSCI 330
C N+++C + +CI W C+ Q++C+ + CI
Sbjct: 1930 CESNEWQCANKRCIPQSWQCDSVNDCLDNSDEDTSHCASRTCRPGQFKCN-----NGRCI 1984
Query: 331 AEYQRCDNITDCADGSDEK--DCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDL 504
+ +CD DC D SDE +C + +C + F C +C C+G DCRD
Sbjct: 1985 PQSWKCDVDNDCGDYSDEPIDECTTAAYNCDNHTEFSCKTNYRCIPQWAVCNGFDDCRDN 2044
Query: 505 SDEKDSCSRNHTACFQY-QFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANE 681
SDE+ S C FRCA+ CI W CDG+ DC D SDE + C ++C+ +E
Sbjct: 2045 SDEQGCES---VPCHPSGDFRCANH-HCIPLRWKCDGTDDCGDNSDE-ENCVPRECSESE 2099
Query: 682 FQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKD 861
F+C +++C P ++ CD +DCGDNSDE +C C P + C +GHC+ + CDG D
Sbjct: 2100 FRCADQQCIPSRWVCDQENDCGDNSDERDCEMKTCHPEHFQCT-SGHCVPKALACDGRAD 2158
Query: 862 CADGADEQQCSQNLCPSLGCQA 927
C D +DE C C A
Sbjct: 2159 CLDASDESACPTRFPNGTYCPA 2180
Score = 155 bits (391), Expect = 4e-35
Identities = 104/292 (35%), Positives = 138/292 (46%), Gaps = 14/292 (4%)
Frame = +1
Query: 268 PGCKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDEKD-CPASTVDCSSQNVFMCAD 444
P C S Q+ C ++ CI + +CD DC+DGSDE D CP F C D
Sbjct: 1846 PMCSSTQFLCG----NNEKCIPIWWKCDGQKDCSDGSDEPDLCPHRFCRLGQ---FQCRD 1898
Query: 445 GRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDC 624
G C C+ + DC D SDE D H C +++CA+K +CI +SW CD DC
Sbjct: 1899 G-NCTSPQALCNARQDCADGSDE-DRVLCEHHRCESNEWQCANK-RCIPQSWQCDSVNDC 1955
Query: 625 ADGSDEPDT-CEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDE--DEC--GEYRCP 789
D SDE + C + C +F+C N RC P+ ++CD +DCGD SDE DEC Y C
Sbjct: 1956 LDNSDEDTSHCASRTCRPGQFKCNNGRCIPQSWKCDVDNDCGDYSDEPIDECTTAAYNCD 2015
Query: 790 -PGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLG---CQAGCHPSPHGGE 957
+++C CI Q +C+G DC D +DEQ C C G C A H P +
Sbjct: 2016 NHTEFSCKTNYRCIPQWAVCNGFDDCRDNSDEQGCESVPCHPSGDFRC-ANHHCIPLRWK 2074
Query: 958 C----TCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDC 1101
C C ++ R CS+ +EF DQ C R + C DC
Sbjct: 2075 CDGTDDCGDNSDEENCVPRECSE----SEFRCADQQCIPSR--WVCDQENDC 2120
Score = 154 bits (389), Expect = 6e-35
Identities = 87/255 (34%), Positives = 118/255 (46%), Gaps = 5/255 (1%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTE--WXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCI 330
C F+C DG C + H C+S++WQC + CI
Sbjct: 1889 CRLGQFQCRDGNCTSPQALCNARQDCADGSDEDRVLCEHHRCESNEWQCA-----NKRCI 1943
Query: 331 AEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSD 510
+ +CD++ DC D SDE ++ C F C +GR C S KCD DC D SD
Sbjct: 1944 PQSWQCDSVNDCLDNSDEDTSHCASRTC-RPGQFKCNNGR-CIPQSWKCDVDNDCGDYSD 2001
Query: 511 EK-DSCSRNHTACFQY-QFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKC-TANE 681
E D C+ C + +F C +CI + VC+G DC D SDE CE C + +
Sbjct: 2002 EPIDECTTAAYNCDNHTEFSCKTNYRCIPQWAVCNGFDDCRDNSDE-QGCESVPCHPSGD 2060
Query: 682 FQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKD 861
F+C N C P +++CD DDCGDNSDE+ C C ++ C CI +CD D
Sbjct: 2061 FRCANHHCIPLRWKCDGTDDCGDNSDEENCVPRECSESEFRC-ADQQCIPSRWVCDQEND 2119
Query: 862 CADGADEQQCSQNLC 906
C D +DE+ C C
Sbjct: 2120 CGDNSDERDCEMKTC 2134
Score = 122 bits (307), Expect = 2e-25
Identities = 82/229 (35%), Positives = 104/229 (44%), Gaps = 12/229 (5%)
Frame = +1
Query: 376 SDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQY 555
+D K C T +Q F C +G C + KCD DC D SDE + HT C
Sbjct: 1022 NDNKYCVVDTGTRCNQLQFTCLNGH-CINQDWKCDNDNDCGDGSDELPTVCAFHT-CRST 1079
Query: 556 QFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTAN-EFQCKNKRCQPRKFRCDY 732
F C + +C+ + CD DC D SDE C F+ C + EF C N RC P + C+
Sbjct: 1080 AFTCGNG-RCVPYHYRCDYYNDCGDNSDEAG-CLFRNCNSTTEFTCSNGRCIPLSYVCNG 1137
Query: 733 YDDCGDN--SDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQ--QCSQN 900
++C DN SDE C + CPP C T C+ + LCDG DC DG+DE C+ +
Sbjct: 1138 INNCHDNDTSDEKNCPPHTCPPDFTKCQTTNICVPRAFLCDGDNDCGDGSDENPIYCASH 1197
Query: 901 LCPSLGCQA----GCHPSPH--GGECTCPSGYKLDDRFHRTCS-DINEC 1026
C S Q C PS GE C G D TC +N C
Sbjct: 1198 TCRSNEFQCLSPQRCIPSYWFCDGEADCADGSDEPD----TCGHSVNTC 1242
Score = 106 bits (265), Expect = 1e-20
Identities = 99/409 (24%), Positives = 169/409 (41%), Gaps = 11/409 (2%)
Frame = +1
Query: 1933 PMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQK 2112
P+GI+A HP QP NPC +A C +C+LS Y CACP G
Sbjct: 21 PLGITAIHPSRQPPS----------RNPCASASCSHLCLLSAQAPRH---YSCACPSGWN 67
Query: 2113 LVNGK-RCI-DSIDYLLFSSNKIVRGIF--PEINEKALAEAVLPISPISQRRIGMYFEVE 2280
L + C+ +L+ + I+ GI PE+ +A++PIS I ++VE
Sbjct: 68 LSDDSVNCVRGDQPFLMSVRDNIIFGISLDPEVKSN---DAMVPISGIQHG-----YDVE 119
Query: 2281 CDVHGNSFFYADIMDNTIYRIRPDGEGA---APVLVTHNDGLFSMSFDWISKQLYYVDNI 2451
D F Y I+R++ DG AP+ + + ++ DW+S+ +YY
Sbjct: 120 FD-DSEQFIYWVENPGEIHRVKTDGSNRTVFAPLSLLGSS--LGLALDWVSRNIYYTTPA 176
Query: 2452 RNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKGLLFYA----EAMRPAAIY 2619
S+EV+ + + + PV + V P +G L+++ ++ PA I
Sbjct: 177 SRSIEVLTLKGDTRYGKTLIANDGTPLGVGFPVGIAVDPARGKLYWSDHGTDSGVPAKIA 236
Query: 2620 RCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVKLDIDNP 2799
++DG + +++ L + +D E +L W T I + DG + L
Sbjct: 237 SANMDGTSLKILFTGNLQHLEVVTLDIQEQKLYWAVTSRGVIERGNVDGTERMILVHHLA 296
Query: 2800 IPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIP 2979
P + + ++YY ++ I RV K +G ++R+ + + L+ +N
Sbjct: 297 HPWGLVVYGSFLYYSDEQYEVIERVDKSSGNNKVVLRD---NVPYLRGLRVYHRRN--AA 351
Query: 2980 DDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINKENNHSC 3126
D S + C Q+C P CAC GF ++ + SC
Sbjct: 352 DSSNGCSNNPNACQQICLPVPGGMF------SCACASGFKLSPD-GRSC 393
Score = 67.4 bits (163), Expect = 1e-08
Identities = 55/222 (24%), Positives = 84/222 (37%), Gaps = 15/222 (6%)
Frame = +1
Query: 139 NTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHS 318
N C+ +F C +G+C+R + +P C ++Q+ C +
Sbjct: 1323 NCTMRTCSAGEFSCANGRCVRQSFRCDRRNDCGDYSDERGCSYPPCHANQFTC-----QN 1377
Query: 319 VSCIAEYQRCDNITDCADGSDEKD--CPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYD 492
CI + CD DC DGSDE++ C C F C +G C ++ + C+ D
Sbjct: 1378 GRCIPRFFVCDEDNDCGDGSDEQEHLCHTPEPTCPLHQ-FRCDNG-HCIEMGRVCNHVDD 1435
Query: 493 CRDLSDEKDSCSRNH---TACFQYQFRCADK-----TQCIQKSWVCDGSKDCAD---GSD 639
C D SDEK C N ++ + C D C+ + + C D +
Sbjct: 1436 CSDNSDEK-GCGINECLDSSISRCDHNCTDTITSFYCSCLPGYKLMSDKRSCVDIDECKE 1494
Query: 640 EPDTCEFKKC--TANEFQCKNKRCQPRKFRCDYYDDCGDNSD 759
P C +KC + CK C P R C NS+
Sbjct: 1495 SPQLCS-QKCENVVGSYICK---CAPGYIREPDGKSCRQNSN 1532
Score = 62.4 bits (150), Expect = 3e-07
Identities = 28/77 (36%), Positives = 43/77 (55%), Gaps = 1/77 (1%)
Frame = +1
Query: 10642 LRCDKWTGKNETILKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGA-GGNGY 10818
++ +KW G N++++ +V P + +HP RQP NPC + CSHLCL+ A Y
Sbjct: 1 MQANKWHGGNQSVVMYSVHQPLGITAIHPSRQPPSRNPCA--SASCSHLCLLSAQAPRHY 58
Query: 10819 TCSCPDQFVLLSDQKTC 10869
+C+CP + L D C
Sbjct: 59 SCACPSGWNLSDDSVNC 75
>gi|48137733|ref|XP_393369.1| similar to ENSANGP00000014849 [Apis
mellifera]
Length = 4275
Score = 1527 bits (3954), Expect = 0.0
Identities = 990/3010 (32%), Positives = 1493/3010 (48%), Gaps = 137/3010 (4%)
Frame = +1
Query: 385 KDCPASTVDCSS--QNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCS-----RNHTA 543
K C D S N F C DG C + C+ + DC DE SC+
Sbjct: 5 KGCTYMAADGSGCGVNSFRCLDGT-CIPATLVCNYQKDCESAEDEFQSCTPPDCEAGQIT 63
Query: 544 CFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEP-------------------------- 645
C QY F +KT CI CD + DC DG+DE
Sbjct: 64 CGQYIF---NKTYCIPPHQRCDMTVDCVDGTDEAGCRNVNRMIFDVEVQHQNFVSQKRRN 120
Query: 646 ---------------------DTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDE 762
+F++CT ++F+C N C PR + CD Y DC D SDE
Sbjct: 121 AMVIWIVEMVVMRRNVRIIRNQLVDFQQCTMDQFRCANSLCIPRSYVCDGYKDCHDGSDE 180
Query: 763 DECGEYRCPPGKWNCP-----GTGHCIDQLKLCDGSKDCADGADEQQ-CSQNLCPSLGCQ 924
C CP K+ CP G CID+ ++CDG DC D ADE+ CS +C SL C+
Sbjct: 181 KSCTTTSCPQNKFVCPRGTTDGKPLCIDRSQICDGKTDCEDKADEEATCSSVICTSLACR 240
Query: 925 AGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCF 1104
C SP GG C CP+G+ L + TC D +EC+E+G+C+QLC N +TCSC F
Sbjct: 241 YKCRASPTGGVCYCPAGWILAND-STTCIDRDECSEWGFCEQLCKNTEGSYTCSCAPG-F 298
Query: 1105 TLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKLASGEFIYG 1284
LQ G + + + K++L VA+ + ++R++ D + +A+ G
Sbjct: 299 ILQ-----GLNKCRAQ----QHPGVKLELLVAQEKAVWRMSSNGEDRTI--VANTTSASG 347
Query: 1285 IDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYII 1464
+D+ Y +FW+D S ++ EG S++ + L S P +AVDWI LY++
Sbjct: 348 VDYLYSRDLLFWSDVKTKKVHSEPLNGEGSSSRVA-IYLTSSWGPVSIAVDWIGEKLYVV 406
Query: 1465 ESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTNQLKLEAAAMDGTNRRT 1644
+S ++IDV DG + L+ LT P DI LDP G MF + ++ A MDGT
Sbjct: 407 DSVVQKIDVLELDGRYHGIALSSNLTNPTDIGLDPTVGLMFIADSKRVLRANMDGTVDFP 466
Query: 1645 LVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALF 1824
+V ++VSGI VD+ A+R++W D ++D +E+ DY G +R +V +G + P P L LF
Sbjct: 467 IVFEAAYKVSGIAVDVIARRIFWCDSQLDYIETADYLGRNRVMVLRGTHT-PSPTRLTLF 525
Query: 1825 DQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPM----GISAYHPMAQPGPGQSEC 1992
+ +YWTD T+ ++ V+K D + ++ M I HP+ QP
Sbjct: 526 ENRIYWTDGTKQAIMSVDKTEGDYSI------RTIYKMRDAKAIKTLHPLTQP------- 572
Query: 1993 LAMKIENPC--TNADCEGMCILSKDNGGFG-VGYKCACPIGQKLVNGKRCIDSI-DYLLF 2160
+ NPC N C+ MCI++ + +GY+CAC IG +L + +R + + ++L++
Sbjct: 573 ---MVSNPCGNNNGGCQHMCIVTAASDQENRLGYRCACDIGWRLSSDQRNCNLVQEFLMY 629
Query: 2161 SSNKIVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYR 2340
S + ++G + + ++A+ P+ R +G+ + D + +Y+D++ + IYR
Sbjct: 630 SQQRFIKGRVLDPVMEGFSDAISPVVSRRARFVGLDY----DAYDQYIYYSDVLQDVIYR 685
Query: 2341 IRPDGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRR 2520
+R G G VL + N+G+ ++ DW++K LYY+D+ + +L V+ RR
Sbjct: 686 VRQSGAGREVVLASQNEGVEGLAVDWVAKNLYYIDSRKGTLNVLSTRNV-------TYRR 738
Query: 2521 QLITELRDPVSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDF 2700
L+ L+ P ++V+HP +G +F++E RPA I R + DG N V +N +LG P+ +AIDF
Sbjct: 739 TLLKNLKRPRAIVIHPNQGYIFFSEWDRPANISRAYTDGSNLIVFKNLSLGWPNGLAIDF 798
Query: 2701 AENRLCWGDTLLKTISCMDFDGKNV--VKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRV 2874
A++RL W D LL + + +G +V VK + P ++ I +++Y R +I R+
Sbjct: 799 AKDRLYWCDALLDHVQHSNLNGTDVRSVKSKLIRH-PFSMAIYEQWMYITDWRLDAIIRL 857
Query: 2875 HKKNGGGSKI-VREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQ--CTQLCFATPS 3045
HK+ G I VR+ + ++ +K S Q D HPC C +LCFA P
Sbjct: 858 HKETGEQESILVRQ--PETNRLYGVKVYSRSIQTFLHD---HPCFNDNGGCEKLCFAIPQ 912
Query: 3046 ESHPN----ELEAKCACRQGFMINKENNHSCQKDPAEKIEQLCSSNSTQFQCKNGRCIPK 3213
+ L C C G I +EN +C DP + N+ F C N RCI
Sbjct: 913 NNTNKYGITRLTKVCGCPYGERI-QENGRTCAPDPEAEPPLEACPNTWDFTCANQRCISH 971
Query: 3214 EWKCDGENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXX 3393
W CDGENDCLD SDE + C T CA N +C++ + C+P
Sbjct: 972 AWVCDGENDCLDNSDERN-----CTKPT-CAPNQFQCKSGR-CVPMSFLCDSENDCGD-- 1022
Query: 3394 XXXVKYCKDGQKP--VCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNATCAA 3567
Y + P C A +F C N+RCIP WK E + C TC+
Sbjct: 1023 -----YSDEASCPNVTCTANQFACANNRCIPNTWKCDSENDCGDSSDEG-DFCVAKTCSY 1076
Query: 3568 NQFSCA-NGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQCVPLRNHX 3744
QF+C +G CIP W+CDGDNDC+D +D+ CPPV C + QF CA+ + CV L ++
Sbjct: 1077 FQFTCPRSGHCIPRSWVCDGDNDCFD--QQDEMDCPPVTCLSTQFTCADQKMCV-LDSYK 1133
Query: 3745 XXXXXXXXXXXXXXX--AVTAESCTPD-QFKCVSSGLCIPASWKXXXXXXXXXXSDEPKF 3915
++ + C D QF+C SS +CIP SW SDEP
Sbjct: 1134 CDGISDCNDGSDEVGCPSLAPDQCNTDKQFQCASSAICIPRSWYCDGTPDCPDRSDEPAS 1193
Query: 3916 GCTSGRQCSSDQFKCGNGRCILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVA 4095
G C FKC N +C+ ++CDG++DCGDGSDE +E T+ KC +
Sbjct: 1194 CGQVG--CQPGFFKCRNEKCVFKAYICDGKDDCGDGSDEDTELHACTAPEF-KCDSQQWK 1250
Query: 4096 CENDQETCIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCSFKCHNSPNGPICSCPF 4275
C N C+ + +CD K CP G DEG C C CS C +P G C+CP
Sbjct: 1251 CPNVTNICVNITSVCDNKFDCPNGADEGPACNFQECEYRGGYCSNDCIETPLGKQCTCPS 1310
Query: 4276 GEQLVNKT--KCEPENECLDSSSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKD 4449
GE+L NK CE NEC CSQ C + K G+ C+C EGY L+ DK TCK A N
Sbjct: 1311 GEEL-NKDGYTCEDLNECEPPGRCSQICVNIKRGYYCNCVEGYTLEKDKHTCK-AFNHSV 1368
Query: 4450 TRIYVSNRNRIYYSDHKLDNWHTFGAIVENAIALAWDSLTDRIYWSDIREKKILSANRNG 4629
+ +SNR+ I +D + VEN +A A + T I+WSD++ KKI +R G
Sbjct: 1369 AFLIISNRHTILVADLQDQALERVPINVENVVATASNMHTGTIFWSDMKLKKISRLDR-G 1427
Query: 4630 TNATVFIADGLDITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRG 4809
++ I+ GLD+ EG+A DW+G NLYW+DS LNTIEVA E R +LV +N++QPRG
Sbjct: 1428 SDPEDVISTGLDLVEGLAYDWIGHNLYWLDSKLNTIEVAK-ETGSNRMILVKENITQPRG 1486
Query: 4810 IAVDPRKGV--MFWTDWGQNPCIERASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFAD 4983
+ +DP G +FWTDWG+NP IER MDGT+R I+ TKIYWPN +ALD R+YFAD
Sbjct: 1487 MCLDPSPGARWLFWTDWGENPRIERIGMDGTNRSTIINTKIYWPNGLALDIANKRIYFAD 1546
Query: 4984 SKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTT 5163
SKLDFID YDGS R QVLASS ++ HPH+L +FED MY++DR+L ++ K+ G
Sbjct: 1547 SKLDFIDTCLYDGSKRIQVLASSHYLLHPHSLTLFEDTMYWTDRQLNRVLSAHKF-YGVN 1605
Query: 5164 SEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTNPCSHLCLLN--NKNTFTCKCPMGEKLD 5337
SH S+ L + HPVLQP+ N PC+ + C HLCLL+ +TCKC +G +L
Sbjct: 1606 QTVVSHLISQPLSIHVHHPVLQPITAN-PCANSTCDHLCLLSPTKPQGYTCKCQVGFRL- 1663
Query: 5338 ASGKKCIDDAKPFLVIIQKTNVFGIEMNSASEKETPVLAGMVPLSGLGNAFDAAYDALSE 5517
+C+++ P+L++++ + + + + S K + P+ G+ + YD +
Sbjct: 1664 -FNGQCLEEEIPYLMVLRGSQIVDVSLLPRSIKTGYI----TPVVGVESGKFIDYDRKEK 1718
Query: 5518 EMFILEHTNHAKTLAQITTDSAIYRSTVNGGNKTKMFS----SAVPDDAYCLGFDWNGRN 5685
++ L+ T + IY + NGGN+T+ + S + + FDW GRN
Sbjct: 1719 MIYWLQ------TKDDDDENGTIYTTPYNGGNRTEFPNASGESGIVGAPSAMAFDWLGRN 1772
Query: 5686 LVVGNKITQTIEIIRTQGK-QYRSVILSNDQSXXXXXXXXXXXXXXXKGYVFWLDRGGGA 5862
L +GNK IE I+ GK +YR+++L+ND + +G++FW+D G
Sbjct: 1773 LFIGNKYASNIEAIKIDGKTKYRTIVLANDGNKTSVAKPKAMCVDPLEGHIFWVDGGSFG 1832
Query: 5863 ADAKVARAGLDGSNPLVIASNDLAELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHY 6042
K+ R +DG+NP+++ N + + I ID +YFS I +++ DGQ+
Sbjct: 1833 IPTKIGRVNMDGTNPIILVDN-VERPEAITIDIPTKTIYFSSLYPALIMALSTDGQNLRT 1891
Query: 6043 VLSDGGRQPNGLAFYGDRLFYADSAFDSIEVATINGDSQPPQWTHFKKDVENLANIKALQ 6222
++S P LA + RL+ D +D IE + P +++ L K
Sbjct: 1892 IVSQNIALPKALAVHDSRLYLLDPLYDKIERVDLPDGGNPTTIIDNDSELKTLTIYK--- 1948
Query: 6223 PRASSSGHPCHINNGNCDHICIPLMFAQRTCTCANGYVKDGQTSCKLFDESFVIVATKTK 6402
+ + HPC INNG+C+ IC+P R C C Y K TSC+ F ++F +V
Sbjct: 1949 -KRITGDHPCFINNGDCEQICLPASGGTRVCACGMEYRKVSDTSCEPF-KTFAVVTQLDV 2006
Query: 6403 VIGYPIDETQSKGVAMEPIGGLS--ITGVDYDYESKTIYVAEAS-GINKGITAYTIGESS 6573
GY + + + AM PI G+ I VD IY E + G+ GI +
Sbjct: 2007 ARGYSLKDAKE---AMVPISGIGHHILHVDVYTAGNWIYWVEFNRGMWNGIFRVRPNGTE 2063
Query: 6574 PRAVIRDSIGSLTIKSLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPS 6753
+ V++ IGS I+ LAIDW+ NMYF N +EV KLDG+ RK+L+ T++P
Sbjct: 2064 LQHVVKQGIGSNGIRGLAIDWVAENMYFTNVFPHDNYVEVCKLDGSNRKVLVKKTTDSPR 2123
Query: 6754 SIAVDPVSRYLYWADQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDA 6933
+AV+P+ +YLYW D GQ P + +++LDGS IV+SGI+ P D+ +D + +YW D+
Sbjct: 2124 ELAVNPIKKYLYWIDYGQYPRLGKAYLDGSNWMPIVTSGISTPRDITIDPITHDVYWVDS 2183
Query: 6934 KMDGIYRVRSTGGTPELVRSDIASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLS 7113
K D I +V TGG +++R ++ + GVA++G ++YW D L +F+A SK N + S
Sbjct: 2184 KQDTIQKVSYTGGNRQIIRRNLPNPMGVAIYGNDVYWVDRNLGIVFKA-SKQNDNN---S 2239
Query: 7114 PTTVAASLKDIGDVAVFSSNNQ-PRASSPCQITDNLRKSPCTQLCFATPGTQTP--TCSC 7284
TV ++L + D+ +F N+Q P ++PC + N + C QLCFA P + C C
Sbjct: 2240 SVTVRSNLPKLRDIVMFDQNSQPPDPTNPCSSSGN---AGCKQLCFAMPKENSVPFKCEC 2296
Query: 7285 ARG--VLKGRTCEEPDTYIMFSDGDKIIDVAIEPDVKASRPLKDPFPEISNLQTFDVDVN 7458
A G + G+ CE + Y++F+ +I + ++P + P +P ++N+ D D
Sbjct: 2297 AVGKLAIDGKNCENVNEYLVFATRTEIRAIGLDPQ-NTTIPF-NPIGNLTNVVGVDFDYQ 2354
Query: 7459 LRRVYFVVESPVGVNISWFSMNNAENPRLVFGASKQPHAKEIRHIS--DMKLDWLTQKIY 7632
+++ F P I+W AENP +S + H + I+ + DW +K+Y
Sbjct: 2355 DKKLLFTQIRP-WAKIAWM---QAENP-----SSSEIHTLISKGINPEGISYDWTQKKVY 2405
Query: 7633 FTTGRGGKVMAIDTAGEHLSTIASGDWTYALAIDPCSGLLFWSDSG-YKTSGGLYEPRIE 7809
+T + A+D G +L IA D A+ +DPC+G L+++D G + TSG +I
Sbjct: 2406 WTDSSNNSIYAMDLNGSNLVMIARVDRPRAIVVDPCNGSLYFTDWGRFGTSG-----KIF 2460
Query: 7810 RSNLAGGSRKVIVSESISLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGYR 7989
++ +AG +K ++ + +S P+ +A+D+ + + D +RL E +N +S +
Sbjct: 2461 KTTMAGSLKKAVIDKDLSQPSGLAIDYEDPECKCDDNSRLVNEDRMCVPKNVTCDSSKFA 2520
Query: 7990 AKSLDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQV 8169
++ R ++ D D + G G SD S ++ R N
Sbjct: 2521 CRNGRCISR-MWACDG--------DDDCGDG-----SDEDTNYCSYHSCSPNEFRCNNGR 2566
Query: 8170 CNALTSQLCKTDNGGCDQLCTVVADDIGLA---ASKVQCSCNDTYELVQEPGKDYPTQCV 8340
C T + C +N C +D+ G + + +C + + Q + C
Sbjct: 2567 CIFKTWK-CDHEND-----CRDGSDEEGCVYPPCAAGEFTCANYRCIPQSQVCNGINDCK 2620
Query: 8341 LRGSNSEPAKEC-----LPPYNFQCGDGS-CILLGATCDSKPDCADASDENPNYCNTRSC 8502
++ E + C PP + +C + C+ CD DC D SDENP +C R+C
Sbjct: 2621 DNVTSDETHERCPRNTTCPPNHLKCEKTNICVEPYWLCDGDNDCGDNSDENPLHCAQRTC 2680
Query: 8503 PEDYNLCTNRRCIDSAKKCNHIDDCGDGSDELD--CPS-AVACAEGTFPCSNGHCINQTK 8673
P+ C N RCI + C+ DDC DGSDE C S C F C NG+CI +
Sbjct: 2681 PQSSFRCPNHRCIPATWYCDGDDDCLDGSDEPPGYCQSEGRTCFGDLFTCDNGNCIPRIY 2740
Query: 8674 VCDGHND------------CHDEQVSDESLATCPGLPI----DCRGVKVRCPNTNICIQP 8805
+CDG ND C+D + +E+ TC + C K C C+
Sbjct: 2741 ICDGDNDCLDYSDEDERHQCNDRKCDEETEFTCTANKVWHRAQCIPKKWLCDGDPDCV-- 2798
Query: 8806 ADLCDGYDDCGDKADENQL--FCMNQQCAQ-HYVRCPSGRCIPETWQCDGDNDCSDGWDE 8976
D D DDCGD +DE+ N C+ C +G CI + C+ + DC+D DE
Sbjct: 2799 -DGADENDDCGDHSDEDGCPPKMKNMTCSNPKEFMCANGICIDQQLVCNKEPDCADESDE 2857
Query: 8977 -THTNCTDTA 9003
H N + A
Sbjct: 2858 PAHCNVDECA 2867
Score = 1068 bits (2761), Expect = 0.0
Identities = 695/2198 (31%), Positives = 990/2198 (44%), Gaps = 74/2198 (3%)
Frame = +1
Query: 7804 IERSNLAGGSRKVIVSESISLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASG 7983
++ N + ++S+ I+ P I+ D+ +K+YW D + +I D +G N +IA
Sbjct: 2372 MQAENPSSSEIHTLISKGIN-PEGISYDWTQKKVYWTDSSNNSIYAMDLNGSNLVMIARV 2430
Query: 7984 YRAKSLDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRN 8163
R +++ + DP + ++ D G + + G+L+ + D+ +
Sbjct: 2431 DRPRAIVV--------DPCNGSLYFTDW-GRFGTSGKIFKTTMAGSLKKAVIDKDLSQPS 2481
Query: 8164 QVCNALTSQLCKTDNGGCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVL 8343
+ + +C C+D LV E CV
Sbjct: 2482 ---------------------------GLAIDYEDPECKCDDNSRLVNED-----RMCVP 2509
Query: 8344 RGSNSEPAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLC 8523
+ + +K F C +G CI CD DC D SDE+ NYC+ SC + C
Sbjct: 2510 KNVTCDSSK-------FACRNGRCISRMWACDGDDDCGDGSDEDTNYCSYHSCSPNEFRC 2562
Query: 8524 TNRRCIDSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHD 8703
N RCI KC+H +DC DGSDE C CA G F C+N CI Q++VC+G NDC D
Sbjct: 2563 NNGRCIFKTWKCDHENDCRDGSDEEGCVYP-PCAAGEFTCANYRCIPQSQVCNGINDCKD 2621
Query: 8704 EQVSDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQC 8883
SDE+ CP C ++C TNIC++P LCDG +DCGD +DEN L C + C
Sbjct: 2622 NVTSDETHERCP-RNTTCPPNHLKCEKTNICVEPYWLCDGDNDCGDNSDENPLHCAQRTC 2680
Query: 8884 AQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCIS 9063
Q RCP+ RCIP TW CDGD+DC DG DE C + C GD LF CDN CI
Sbjct: 2681 PQSSFRCPNHRCIPATWYCDGDDDCLDGSDEPPGYCQSEG--RTCFGD-LFTCDNGNCIP 2737
Query: 9064 RAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQ-EFHCTSNAKLAQPKYECIPRAWLCDGDV 9240
R +I RH C +R C ++ EF CT+N + +CIP+ WLCDGD
Sbjct: 2738 RIYICDGDNDCLDYSDEDERHQCNDRKCDEETEFTCTANK--VWHRAQCIPKKWLCDGDP 2795
Query: 9241 TCAGGEDESTEL--------CKTEKKE---CNKGEFRCSNQHCIHSTWECDGDNDCLDGS 9387
C G DE+ + C + K N EF C+N CI C+ + DC D S
Sbjct: 2796 DCVDGADENDDCGDHSDEDGCPPKMKNMTCSNPKEFMCANGICIDQQLVCNKEPDCADES 2855
Query: 9388 DEHANCTYSSC-QPDFFQCANHKCV--PNSWKCDGNDDCEDGSDEKDCPKNSASAQKASK 9558
DE A+C C + QCA HKC+ P S+ C+
Sbjct: 2856 DEPAHCNVDECAMVEMNQCA-HKCIDTPTSYYCE-------------------------- 2888
Query: 9559 CSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKP-LCEQKCMDMKIG 9735
C+ G G+ +D IDEC E P +C Q+C +
Sbjct: 2889 CNPGYRLLADGKACED---------------------IDEC--VETPQVCSQQCQNTPGS 2925
Query: 9736 YKCDCFEGFAIDISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSC 9915
+ C C + +D+ +C
Sbjct: 2926 FYCKCNHYWYERAADEHTCK---------------------------------------- 2945
Query: 9916 KRTEMEPEPFFLLANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLIDQGKLR 10095
+R + P + + NK+Y+R +SID Y L Q NVV+LD D ++ Y D
Sbjct: 2946 RRDNIIP--WIIFTNKYYVRNMSIDALNYSLMHQDLINVVALDADYGDQMLYFCDVTAKT 3003
Query: 10096 LLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCK 10275
+ R + + E ++RH+ G EGIAVDW+GRKLY L+R + + V EL+G K
Sbjct: 3004 IFRAPIAGGEK-----EAIIRHDSLGLEGIAVDWIGRKLYWLDRHAKHLDVAELNGTNRK 3058
Query: 10276 TLIRDRIQQPKAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPN 10455
TL+ I P+AIVVHPG GYL+FT W LQ YIG++ +DGS + E D+ WPN
Sbjct: 3059 TLLTG-IADPRAIVVHPGTGYLYFTSWHLQAYIGKMGMDGSNFTR---ILTWEDDIAWPN 3114
Query: 10456 AIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHI-PAQRTSHVSSMVVFDDYLYWADWNL 10632
A+ IDYF+DR+FW DAHL+ I F D +G+ RR + HV ++ +FDD+++W DWNL
Sbjct: 3115 ALTIDYFTDRIFWADAHLDYIAFADLEGHNRRKVLSGTAVPHVFAITIFDDFIFWTDWNL 3174
Query: 10633 REVLRCDKWTGKNETILKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIG---- 10800
+ + R +K++G N +L+ T P D+ HP+RQ Y NPC +NNGGCSHLCLI
Sbjct: 3175 KAISRAEKFSGYNLRVLRNTTHRPYDIHAYHPLRQLPYNNPCNENNGGCSHLCLISPPAS 3234
Query: 10801 ---------AGGNGYTCSCPDQFVLLSDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGE 10953
G Y C CP+QFVL D KTC NCT Q CG D KCIP W CDGE
Sbjct: 3235 SYLLEGYGQPGVTSYKCKCPNQFVLDKDGKTCTANCTAGQHKCGPPDEKCIPWYWKCDGE 3294
Query: 10954 PDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXXEQNCDKACDP 11133
DC+DGSDEP C R+C FQC N NC + E +C C
Sbjct: 3295 KDCKDGSDEP--ISCPARVCRPSVFQCANGNCRPSVAVCDGADDCGDKSDEAHCSLECGE 3352
Query: 11134 WMFKCAATGRCIPRRFTXXXXXXXXXRSDEADTLCMSAERNCTAE-EFRCNNNKCIAKAW 11310
FKC + GRCI + SDE +C + R C EF C NN+CI K W
Sbjct: 3353 LEFKCKSNGRCIHESWKCDGDADCKDGSDEDPAICHN--RPCDPNTEFTCKNNRCIQKVW 3410
Query: 11311 RXXXXXXXXXXXXETP-ECAQIECKKGWTRC--SSSYRCIPNWAFCNGQDDCRDNSDEDK 11481
E C Q C GW RC ++YRCIP W FC+G+DDCRD SDE
Sbjct: 3411 MCDSDNDCGDDSDEPAYMCRQRNCTTGWQRCPGHANYRCIPKWLFCDGKDDCRDGSDELA 3470
Query: 11482 QRCPTCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCND 11661
+ CP CD +F+C T+ +C+P++W+CD +DCGD SDE + C R CSESEFRC++
Sbjct: 3471 ENCPKCDPEMDFKC-TNNRCVPKQWLCDFADDCGDGSDEAETMCKNRYRECSESEFRCDN 3529
Query: 11662 GKCIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAAD 11841
GKCI CD C D DE+ C C QC G CIA + CD +DC + +D
Sbjct: 3530 GKCIASRWRCDSEDDCGDNSDENGCQEFVCKNDTFQCASGHCIASYLRCDGTRDCRDMSD 3589
Query: 11842 ELHCED--VSRRTCSPFEFECANSVCIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPLR 12015
E+ C R C F+C N++C+ + SDE ++ C + +CD R
Sbjct: 3590 EIGCPPRYPGGRYCPQSRFQCDNNLCVYLSDICDGSDDCGDGSDENTNMCANFKCDTTRR 3649
Query: 12016 FRCAHSRLCLNILQLCNGFNDCGPNDFSDE-HLSMCSSFSEYGDCSSDQFKCANGKCVNG 12192
F+CA+ + C+ QLC+G ++CG D SDE +++MC+S D + ++ CAN KC+
Sbjct: 3650 FQCANHK-CIAKYQLCDGIDNCG--DGSDENNMTMCASRVRPCDAIT-EYTCANKKCIER 3705
Query: 12193 TVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKHICTDVRDGFY-CHCRDGFRPD 12369
T CD DDCGD+SDE+GC H K ++ N GGC H C ++ +G Y C C G+
Sbjct: 3706 TKLCDFADDCGDSSDELGC--HHNKPCLDS--NKGGCSHYCHNITEGGYICACYPGYIIS 3761
Query: 12370 PQSPKECIDIDEC-AGNNTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAA 12546
+ K C DI+EC G + C+QLC N G+Y C C + +E + CRA
Sbjct: 3762 QNNRKHCEDINECVTGQHQCSQLCTNLNGTYSCSCRQGFE----LSDNRSGVCRA----- 3812
Query: 12547 NVMIGADDSLVQLSLHGSGTNRH-----XXXXXXXXXXXXXXXXXXPRKELMYWIDGSER 12711
D +++ L +G G + PR E ++WIDG
Sbjct: 3813 -----VDTNMMILFANGPGIRAYDPYDKQEIEVIANEKRVQALDFDPRSEYVFWIDGESG 3867
Query: 12712 TIYRSAIANGNQSHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAVSENIENGLVTARK 12891
T++A+D+ +GNL+
Sbjct: 3868 L-----------------------------TSLAMDWISGNLYWT--------------- 3883
Query: 12892 KRMSEPIDNQNT---GFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLH- 13059
D+ T G + V DGRY + ++ L+ PT+++ P G+ ++D L+
Sbjct: 3884 -----EFDSSGTTLFGRVMVSKADGRYRRSLITVGLEIPTSIVVDPELGKAIWADHVLYW 3938
Query: 13060 -----AKIECADMDGTHRQIIVK-DLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDG 13221
IE + DG++R+II+K D + P S+ + E N +YW+
Sbjct: 3939 ADSKLNTIESIEQDGSNRKIILKGDSLKHPISLDVFE---NSLYWI-------------- 3981
Query: 13222 SERTTVVHDRHIPYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRV- 13398
++ + L QDKFGRG ++ + + V+V
Sbjct: 3982 --------------------------TKRTGELIRQDKFGRGVPEIIVKHVPNSGGVKVY 4015
Query: 13399 -SQKYAKDTQRTVSGCERAQCSHLCVSLPSTGFACLCPDGIVP--------QLDGSCATQ 13551
Q+Y + C QC+HLCV +P G CLC D I P + C
Sbjct: 4016 HQQRYNISLRNL---CHEDQCTHLCVPIPG-GNRCLCSDSIGPLQQRETIRSNERHCDAT 4071
Query: 13552 HVEALTMPKQCKCTNGGKCRL---DGSCECTSDFEGDQCEKESSVSRKIIGTLSENFITV 13722
+ L P+ C C NGG C+ C+C + F G+ CE ++G S N
Sbjct: 4072 NERPLPAPRICPCRNGGLCQEVEDKLQCDCPAPFHGEFCE-------IMLGARSTNATAA 4124
Query: 13723 XXXXXXXXXXXXXXXXXXXNLYKRRQLLFKK-----NEAADGSVSF-HGNVISFSNPVLE 13884
+ K+R F K + SVSF G+ + F P E
Sbjct: 4125 IVIPIVVSILVLFGAAAIIMVLKKRP--FGKPGGLGSLTGAQSVSFRQGSNVEFGIPAHE 4182
Query: 13885 NKQDAPGSEFNMQQMTSMHDDSTTFTNPVYELEDVDMSSPPPSNDQPSTSASAMSPNRPS 14064
+ + E+N+ +++ + D F+NP+Y D +T A +
Sbjct: 4183 -RMEPLDVEYNLGDVSNKNRD---FSNPMY--------------DAVNTETGATN----G 4220
Query: 14065 TSAASSF-VPPTFDQDEIELKTADEIIVPKAEISKPPI 14175
T A+S + +P I+ K ++ + + E+ PI
Sbjct: 4221 TGASSRYELPAEMKPSSIQHKEPPQLHLKRRELDPTPI 4258
Score = 464 bits (1195), Expect = e-128
Identities = 390/1572 (24%), Positives = 649/1572 (40%), Gaps = 40/1572 (2%)
Frame = +1
Query: 6265 GNCDHICIPLMFAQRTCTCANGYVKDGQTSCKLFDESFV---IVATKTKVIGYPIDETQS 6435
G C+ +C TC+CA G++ G C+ V ++ + K + +
Sbjct: 277 GFCEQLCKNTE-GSYTCSCAPGFILQGLNKCRAQQHPGVKLELLVAQEKAVWRMSSNGED 335
Query: 6436 KGVAMEPIGGLSITGVDYDYESKTIYVAEASGINKGITAYTI-GESSPRAVIRDSIGSLT 6612
+ + S +GVDY Y ++ ++ K + + + GE S V S
Sbjct: 336 RTIVANTT---SASGVDYLYSRDLLFWSDVK--TKKVHSEPLNGEGSSSRVAIYLTSSWG 390
Query: 6613 IKSLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYW 6792
S+A+DWI +Y ++ ++ I+V +LDG Y I L++ P+ I +DP ++
Sbjct: 391 PVSIAVDWIGEKLYVVDSVVQK--IDVLELDGRYHGIALSSNLTNPTDIGLDPTVGLMFI 448
Query: 6793 ADQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGG 6972
AD + + R+ +DG+ IV + + + VDV ++ I+W D+++D I G
Sbjct: 449 ADSKR---VLRANMDGTVDFPIVFEAAYKVSGIAVDVIARRIFWCDSQLDYIETADYLGR 505
Query: 6973 TPELVR--SDIASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDI 7146
+V + S + L +YWTD + + S+ ++D
Sbjct: 506 NRVMVLRGTHTPSPTRLTLFENRIYWTDGTKQAIMSVDKTEGDYSI-----RTIYKMRDA 560
Query: 7147 GDVAVFSSNNQPRASSPCQITDNLRKSPCTQLCFATPGTQTPT-----CSCARGVLKG-- 7305
+ QP S+PC C +C T + C+C G
Sbjct: 561 KAIKTLHPLTQPMVSNPC----GNNNGGCQHMCIVTAASDQENRLGYRCACDIGWRLSSD 616
Query: 7306 -RTCEEPDTYIMFSDGDKIIDVAIEPDVKASRPLKDPFPEISNLQTF---DVDVNLRRVY 7473
R C ++M+S I ++P ++ P +S F D D + +Y
Sbjct: 617 QRNCNLVQEFLMYSQQRFIKGRVLDPVMEGFSDAISPV--VSRRARFVGLDYDAYDQYIY 674
Query: 7474 FVVESPVGVNISWFSMNNAENPRLVFGASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGG 7653
+ S V ++ + + +V + + + + +DW+ + +Y+ R G
Sbjct: 675 Y---SDVLQDVIYRVRQSGAGREVVLASQNEG-------VEGLAVDWVAKNLYYIDSRKG 724
Query: 7654 KVMAIDTAGE--HLSTIASGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAG 7827
+ + T + + + A+ I P G +F+S+ + I R+ G
Sbjct: 725 TLNVLSTRNVTYRRTLLKNLKRPRAIVIHPNQGYIFFSEWDRPAN-------ISRAYTDG 777
Query: 7828 GSRKVIVSESISLPAAIAVDFRNQKIYWAD-----VNRLNIEVADYDGQNRKVIASGYRA 7992
+ V + S+ P +A+DF ++YW D V N+ D K+I +
Sbjct: 778 SNLIVFKNLSLGWPNGLAIDFAKDRLYWCDALLDHVQHSNLNGTDVRSVKSKLIRHPF-- 835
Query: 7993 KSLDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVC 8172
S+ I+++W+Y++D + + R+ KE+G +V R P R++ + R+ +
Sbjct: 836 -SMAIYEQWMYITDWRLDAIIRLHKETGEQESILV---RQPETNRLYGVKVYSRS---IQ 888
Query: 8173 NALTSQLCKTDNGGCDQLCTVVADD----IGLAASKVQCSCNDTYELVQEPGKDYPTQCV 8340
L C DNGGC++LC + + G+ C C E +QE G+ C
Sbjct: 889 TFLHDHPCFNDNGGCEKLCFAIPQNNTNKYGITRLTKVCGC-PYGERIQENGRT----CA 943
Query: 8341 LRGSNSEPAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNL 8520
P + C ++F C + CI CD + DC D SDE C +C +
Sbjct: 944 PDPEAEPPLEACPNTWDFTCANQRCISHAWVCDGENDCLDNSDE--RNCTKPTCAPNQFQ 1001
Query: 8521 CTNRRCIDSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCH 8700
C + RC+ + C+ +DCGD SDE CP+ V C F C+N CI T CD NDC
Sbjct: 1002 CKSGRCVPMSFLCDSENDCGDYSDEASCPN-VTCTANQFACANNRCIPNTWKCDSENDCG 1060
Query: 8701 DEQVSDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQ 8880
D SDE C + C + CP + CI + +CDG +DC D+ DE + C
Sbjct: 1061 DS--SDEG-DFC--VAKTCSYFQFTCPRSGHCIPRSWVCDGDNDCFDQQDE--MDCPPVT 1113
Query: 8881 CAQHYVRCPSGR-CIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQC-DNLK 9054
C C + C+ ++++CDG +DC+DG DE C A + C D FQC +
Sbjct: 1114 CLSTQFTCADQKMCVLDSYKCDGISDCNDGSDE--VGCPSLAPDQ-CNTDKQFQCASSAI 1170
Query: 9055 CISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDG 9234
CI R++ + CG C F C + +C+ +A++CDG
Sbjct: 1171 CIPRSWYCDGTPDCPDRSDEPA--SCGQVGCQPGFFKCRNE--------KCVFKAYICDG 1220
Query: 9235 DVTCAGGEDESTEL--CKTEKKECNKGEFRCSN--QHCIHSTWECDGDNDCLDGSDEHAN 9402
C G DE TEL C + +C+ +++C N C++ T CD DC +G+DE
Sbjct: 1221 KDDCGDGSDEDTELHACTAPEFKCDSQQWKCPNVTNICVNITSVCDNKFDCPNGADEGPA 1280
Query: 9403 CTYSSCQPDFFQCANHKCVPNSWKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQC 9582
C + C+ C+N DC + K C C
Sbjct: 1281 CNFQECEYRGGYCSN--------------DCIETPLGKQC------------------TC 1308
Query: 9583 TSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKP-LCEQKCMDMKIGYKCDCFEG 9759
SGE ++ + C D ++EC E P C Q C+++K GY C+C EG
Sbjct: 1309 PSGE-----ELNKDGYTCED---------LNEC---EPPGRCSQICVNIKRGYYCNCVEG 1351
Query: 9760 FAIDISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPE 9939
+ L D H+CK
Sbjct: 1352 YT------------------------------------------LEKDKHTCKAFN-HSV 1368
Query: 9940 PFFLLANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDE 10119
F +++N+H I + E +NVV+ ++ + D ++ R+D
Sbjct: 1369 AFLIISNRHTILVADLQDQALERVPINVENVVATASNMHTGTIFWSDMKLKKISRLDRG- 1427
Query: 10120 MDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQ 10299
S E V+ + EG+A DW+G LY L+ + +I V + G L+++ I
Sbjct: 1428 -----SDPEDVISTGLDLVEGLAYDWIGHNLYWLDSKLNTIEVAKETGSNRMILVKENIT 1482
Query: 10300 QPKAIVVHPGKG--YLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDY 10473
QP+ + + P G +LF+T+W P I RI +DG+ + + WPN +A+D
Sbjct: 1483 QPRGMCLDPSPGARWLFWTDWGENPRIERIGMDGTNR-----STIINTKIYWPNGLALDI 1537
Query: 10474 FSDRLFWGDAHLNEIGFMDFDGNGRRHIPAQR--TSHVSSMVVFDDYLYWADWNLREVLR 10647
+ R+++ D+ L+ I +DG+ R + A H S+ +F+D +YW D L VL
Sbjct: 1538 ANKRIYFADSKLDFIDTCLYDGSKRIQVLASSHYLLHPHSLTLFEDTMYWTDRQLNRVLS 1597
Query: 10648 CDKWTGKNETILKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIG-AGGNGYTC 10824
K+ G N+T++ + P + + HP+ QP NPC N C HLCL+ GYTC
Sbjct: 1598 AHKFYGVNQTVVSHLISQPLSIHVHHPVLQPITANPCA--NSTCDHLCLLSPTKPQGYTC 1655
Query: 10825 SCPDQFVLLSDQ 10860
C F L + Q
Sbjct: 1656 KCQVGFRLFNGQ 1667
Score = 410 bits (1054), Expect = e-112
Identities = 361/1336 (27%), Positives = 566/1336 (42%), Gaps = 78/1336 (5%)
Frame = +1
Query: 7198 CQITDNLRKSP--CTQLCFATPGTQTPTCS--CARGVLKGRTCEEPDT---YIMFSDGDK 7356
C+ D ++P C+Q C TPG+ C+ TC+ D +I+F++
Sbjct: 2902 CEDIDECVETPQVCSQQCQNTPGSFYCKCNHYWYERAADEHTCKRRDNIIPWIIFTNKYY 2961
Query: 7357 IIDVAIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAEN 7536
+ +++I+ + S +D + N+ D D + +YF +
Sbjct: 2962 VRNMSIDA-LNYSLMHQD----LINVVALDADYGDQMLYFCDVTA--------------- 3001
Query: 7537 PRLVFGASKQPHAKE--IRH----ISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTI 7698
+ +F A KE IRH + + +DW+ +K+Y+ + + G + T+
Sbjct: 3002 -KTIFRAPIAGGEKEAIIRHDSLGLEGIAVDWIGRKLYWLDRHAKHLDVAELNGTNRKTL 3060
Query: 7699 ASGDWT-YALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAA 7875
+G A+ + P +G L+++ + + + ++ SN +R + + I+ P A
Sbjct: 3061 LTGIADPRAIVVHPGTGYLYFTS--WHLQAYIGKMGMDGSNF---TRILTWEDDIAWPNA 3115
Query: 7876 IAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGYRAK---SLDIWDRWLYMSDPLSN 8046
+ +D+ +I+WAD + I AD +G NR+ + SG ++ I+D +++ +D
Sbjct: 3116 LTIDYFTDRIFWADAHLDYIAFADLEGHNRRKVLSGTAVPHVFAITIFDDFIFWTDWNLK 3175
Query: 8047 GVFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQL 8226
+ R +K SG L + + P D+ + + + C +NGGC L
Sbjct: 3176 AISRAEKFSGYNLRVLRNTTHRP---------YDIHAYHPLRQLPYNNPCNENNGGCSHL 3226
Query: 8227 CTV-------VADDIGL-AASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSEPAKECLP 8382
C + + + G + +C C + + ++ + GK C + +C P
Sbjct: 3227 CLISPPASSYLLEGYGQPGVTSYKCKCPNQF-VLDKDGKTCTANC------TAGQHKCGP 3279
Query: 8383 PYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCN 8562
P D CI CD + DC D SDE P C R C C N C S C+
Sbjct: 3280 P------DEKCIPWYWKCDGEKDCKDGSDE-PISCPARVCRPSVFQCANGNCRPSVAVCD 3332
Query: 8563 HIDDCGDGSDELDCPSAVACAEGTFPC-SNGHCINQTKVCDGHNDCHDEQVSDESLATCP 8739
DDCGD SDE C ++ C E F C SNG CI+++ CDG DC D SDE A C
Sbjct: 3333 GADDCGDKSDEAHC--SLECGELEFKCKSNGRCIHESWKCDGDADCKDG--SDEDPAICH 3388
Query: 8740 GLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCP---S 8910
P D + C N N CIQ +CD +DCGD +DE C + C + RCP +
Sbjct: 3389 NRPCD-PNTEFTCKN-NRCIQKVWMCDSDNDCGDDSDEPAYMCRQRNCTTGWQRCPGHAN 3446
Query: 8911 GRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXX 9090
RCIP+ CDG +DC DG DE NC C + F+C N +C+ + ++
Sbjct: 3447 YRCIPKWLFCDGKDDCRDGSDELAENCPK------CDPEMDFKCTNNRCVPKQWL-CDFA 3499
Query: 9091 XXXXXXXXHSRHGCGN--RTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDE 9264
+ C N R C++ EF C + +CI W CD + C DE
Sbjct: 3500 DDCGDGSDEAETMCKNRYRECSESEFRCDNG--------KCIASRWRCDSEDDCGDNSDE 3551
Query: 9265 S---TELCKTEKKECNKG-------------------------------------EFRCS 9324
+ +CK + +C G F+C
Sbjct: 3552 NGCQEFVCKNDTFQCASGHCIASYLRCDGTRDCRDMSDEIGCPPRYPGGRYCPQSRFQCD 3611
Query: 9325 NQHCIHSTWECDGDNDCLDGSDEHAN-CTYSSCQPD-FFQCANHKCVPNSWKCDGNDDCE 9498
N C++ + CDG +DC DGSDE+ N C C FQCANHKC+ CDG D+C
Sbjct: 3612 NNLCVYLSDICDGSDDCGDGSDENTNMCANFKCDTTRRFQCANHKCIAKYQLCDGIDNCG 3671
Query: 9499 DGSDEKDCPKNSASAQKASKC-SNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLCFID 9675
DGSDE + + A + C + ++ C + +CI+ K+CD DC D SDE
Sbjct: 3672 DGSDENNM---TMCASRVRPCDAITEYTCANKKCIERTKLCDFADDCGDSSDELGCHHNK 3728
Query: 9676 ECSLAEKPLCEQKCMDM-KIGYKCDCFEGFAIDISDQKSCHNVNECYEGISGCSQKCDDK 9852
C + K C C ++ + GY C C+ G+ I +++K C ++NEC G CSQ C +
Sbjct: 3729 PCLDSNKGGCSHYCHNITEGGYICACYPGYIISQNNRKHCEDINECVTGQHQCSQLCTNL 3788
Query: 9853 IGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKIS-IDGNKYELAAQGFDN 10029
G+Y C C G++L SD+ S ++ L AN IR D + E+ A
Sbjct: 3789 NGTYSCSCRQGFEL-SDNRSGVCRAVDTNMMILFANGPGIRAYDPYDKQEIEVIANE-KR 3846
Query: 10030 VVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDWVGRK 10209
V +LD D + + ID G+ L + +D + N+Y TE D G
Sbjct: 3847 VQALDFDPRSEYVFWID-GESGLTSLAMDWISG-----------NLYWTE---FDSSGTT 3891
Query: 10210 LYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFFTEWSLQPYIGRIAL 10389
L+ + V + DGR+ ++LI ++ P +IVV P G
Sbjct: 3892 LF------GRVMVSKADGRYRRSLITVGLEIPTSIVVDPELG------------------ 3927
Query: 10390 DGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHI-PAQ 10566
AI D+ L+W D+ LN I ++ DG+ R+ I
Sbjct: 3928 ---------------------KAIWADHV---LYWADSKLNTIESIEQDGSNRKIILKGD 3963
Query: 10567 RTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDLRIVHPMR-QPA 10743
H S+ VF++ LYW E++R DK+ I+ K V +++ H R +
Sbjct: 3964 SLKHPISLDVFENSLYWITKRTGELIRQDKFGRGVPEIIVKHVPNSGGVKVYHQQRYNIS 4023
Query: 10744 YPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTCEPNCTERQFACGGDDAKC 10923
N C ++ C+HLC+ GGN C C D L ++T N ER C + +
Sbjct: 4024 LRNLCHEDQ--CTHLCVPIPGGN--RCLCSDSIGPLQQRETIRSN--ERH--CDATNERP 4075
Query: 10924 IPKLWYCDGEPDCRDG 10971
+P C CR+G
Sbjct: 4076 LPAPRIC----PCRNG 4087
Score = 382 bits (982), Expect = e-103
Identities = 295/1075 (27%), Positives = 460/1075 (42%), Gaps = 78/1075 (7%)
Frame = +1
Query: 139 NTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQ---------- 288
N C N F+C G+C+ + P+ C ++Q
Sbjct: 989 NCTKPTCAPNQFQCKSGRCVPMSFLCDSENDCGDYSDEASCPNVTCTANQFACANNRCIP 1048
Query: 289 --WQCDT-----------------------YTW-HSVSCIAEYQRCDNITDCADGSDEKD 390
W+CD+ +T S CI CD DC D DE D
Sbjct: 1049 NTWKCDSENDCGDSSDEGDFCVAKTCSYFQFTCPRSGHCIPRSWVCDGDNDCFDQQDEMD 1108
Query: 391 CPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTAC-FQYQFRC 567
CP V C S F CAD + C S KCDG DC D SDE S C QF+C
Sbjct: 1109 CP--PVTCLSTQ-FTCADQKMCVLDSYKCDGISDCNDGSDEVGCPSLAPDQCNTDKQFQC 1165
Query: 568 ADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCG 747
A CI +SW CDG+ DC D SDEP +C C F+C+N++C + + CD DDCG
Sbjct: 1166 ASSAICIPRSWYCDGTPDCPDRSDEPASCGQVGCQPGFFKCRNEKCVFKAYICDGKDDCG 1225
Query: 748 DNSDED------ECGEYRCPPGKWNCPG-TGHCIDQLKLCDGSKDCADGADE-QQCSQNL 903
D SDED E++C +W CP T C++ +CD DC +GADE C+
Sbjct: 1226 DGSDEDTELHACTAPEFKCDSQQWKCPNVTNICVNITSVCDNKFDCPNGADEGPACNFQE 1285
Query: 904 CPSLG--CQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGF 1077
C G C C +P G +CTCPSG +L+ + TC D+NEC G C Q+C N + G+
Sbjct: 1286 CEYRGGYCSNDCIETPLGKQCTCPSGEELNKDGY-TCEDLNECEPPGRCSQICVNIKRGY 1344
Query: 1078 TCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKK 1257
C+C+ + +TL+ + K + + +N + + + + L R+ P N + V
Sbjct: 1345 YCNCV-EGYTLEKDKHTCKAFNHSVAFLIISNRHTILVADLQDQALERV-PINVENVV-- 1400
Query: 1258 LASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVD 1437
A+ ++ + D K+ RL + DV G L LA D
Sbjct: 1401 -ATASNMHTGTIFWSDMKLKKISRLDRGSDPEDVISTG------------LDLVEGLAYD 1447
Query: 1438 WITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGE--MFFTN---QL 1602
WI + LY ++S I+V+ G R +L+ + +T P + LDP G +F+T+
Sbjct: 1448 WIGHNLYWLDSKLNTIEVAKETGSNRMILVKENITQPRGMCLDPSPGARWLFWTDWGENP 1507
Query: 1603 KLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQ 1782
++E MDGTNR T++NT + +G+ +DI KR+Y+ D K+D +++ Y G+ R V
Sbjct: 1508 RIERIGMDGTNRSTIINTKIYWPNGLALDIANKRIYFADSKLDFIDTCLYDGSKRIQVLA 1567
Query: 1783 GMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPM 1962
+ + HP L LF+ +YWTD V+ KF + + S+ + P+ I +HP+
Sbjct: 1568 SSHYLLHPHSLTLFEDTMYWTDRQLNRVLSAHKFYGVNQTVVSHLISQ--PLSIHVHHPV 1625
Query: 1963 AQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGKRCIDS 2142
QP NPC N+ C+ +C+LS GY C C +G +L NG+ +
Sbjct: 1626 LQP----------ITANPCANSTCDHLCLLSPTK---PQGYTCKCQVGFRLFNGQCLEEE 1672
Query: 2143 IDYLLFSSNKIVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIM 2322
I YL+ ++RG ++ +S + + Y V F D
Sbjct: 1673 IPYLM-----VLRG-----------SQIVDVSLLPRSIKTGYITPVVGVESGKFIDYDRK 1716
Query: 2323 DNTIYRIR---PDGEGAAPVLVTHNDG-----------------LFSMSFDWISKQLYYV 2442
+ IY ++ D E +N G +M+FDW+ + L+
Sbjct: 1717 EKMIYWLQTKDDDDENGTIYTTPYNGGNRTEFPNASGESGIVGAPSAMAFDWLGRNLFIG 1776
Query: 2443 DNIRNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKGLLFYAEAMR---PAA 2613
+ +++E +KI L T + P ++ V P +G +F+ + P
Sbjct: 1777 NKYASNIEAIKIDGKTKYRTIVLANDGNKTSVAKPKAMCVDPLEGHIFWVDGGSFGIPTK 1836
Query: 2614 IYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVKLDID 2793
I R ++DG N +I + RP + ID + + I + DG+N+ +
Sbjct: 1837 IGRVNMDGTN-PIILVDNVERPEAITIDIPTKTIYFSSLYPALIMALSTDGQNLRTIVSQ 1895
Query: 2794 N-PIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQ 2970
N +P A+ + + +Y + I RV +GG + + ++ LK + +
Sbjct: 1896 NIALPKALAVHDSRLYLLDPLYDKIERVDLPDGGNPTTIIDNDSE------LKTLTIYKK 1949
Query: 2971 PIPDDSREHPC--RASQCTQLCFATPSESHPNELEAKCACRQGFMINKENNHSCQ 3129
I D HPC C Q+C + CAC G K ++ SC+
Sbjct: 1950 RITGD---HPCFINNGDCEQICLPASGGTR------VCAC--GMEYRKVSDTSCE 1993
Score = 368 bits (945), Expect = 2e-99
Identities = 269/944 (28%), Positives = 418/944 (43%), Gaps = 51/944 (5%)
Frame = +1
Query: 2677 PSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVKLD-IDNPIPVAITIMNEYIYYVHQR 2853
P ++ D+ + ++ W D+ +I MD +G N+V + +D P + + N +Y+
Sbjct: 2392 PEGISYDWTQKKVYWTDSSNNSIYAMDLNGSNLVMIARVDRPRAIVVDPCNGSLYFTDWG 2451
Query: 2854 PYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCF 3033
FG + + A S + I D
Sbjct: 2452 -------------------RFGTSGKIFKTTMAGSLKKAVIDKD---------------L 2477
Query: 3034 ATPSESHPNELEAKCACRQGFMINKENNHSCQKDPAEKIEQLCSSNSTQFQCKNGRCIPK 3213
+ PS + + +C C + E+ K+ + +S++F C+NGRCI +
Sbjct: 2478 SQPSGLAIDYEDPECKCDDNSRLVNEDRMCVPKN--------VTCDSSKFACRNGRCISR 2529
Query: 3214 EWKCDGENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXX 3393
W CDG++DC D SDE + C + + C+ N +C N + CI
Sbjct: 2530 MWACDGDDDCGDGSDE---DTNYCSYHS-CSPNEFRCNNGR-CI-----------FKTWK 2573
Query: 3394 XXXVKYCKDGQK------PVCAAKKFQCDNHRCIPEQW--KXXXXXXXXXXXXEKLEMCG 3549
C+DG P CAA +F C N+RCIP+ E E C
Sbjct: 2574 CDHENDCRDGSDEEGCVYPPCAAGEFTCANYRCIPQSQVCNGINDCKDNVTSDETHERCP 2633
Query: 3550 -NATCAANQFSCANGR-CIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQC 3723
N TC N C C+ YWLCDGDNDC D +DE+ C C FRC N R C
Sbjct: 2634 RNTTCPPNHLKCEKTNICVEPYWLCDGDNDCGDNSDENPLHCAQRTCPQSSFRCPNHR-C 2692
Query: 3724 VPLRNHXXXXXXXXXXXXXXXXAVTAE--SCTPDQFKCVSSGLCIPASWKXXXXXXXXXX 3897
+P + +E +C D F C +G CIP +
Sbjct: 2693 IPATWYCDGDDDCLDGSDEPPGYCQSEGRTCFGDLFTC-DNGNCIPRIYICDGDNDCLDY 2751
Query: 3898 SDEPKFGCTSGRQCSSD-QFKCG------NGRCILNNWLCDGENDCGDGSDESSERGCKT 4056
SDE + + R+C + +F C +CI WLCDG+ DC DG+DE+ + G +
Sbjct: 2752 SDEDERHQCNDRKCDEETEFTCTANKVWHRAQCIPKKWLCDGDPDCVDGADENDDCGDHS 2811
Query: 4057 SMNARKCPFEHVACENDQE------TCIPLHQLCDGKTHCPGGTDEGGRCARDLCS-ADR 4215
+ +++ C N +E CI +C+ + C +DE C D C+ +
Sbjct: 2812 DEDGCPPKMKNMTCSNPKEFMCANGICIDQQLVCNKEPDCADESDEPAHCNVDECAMVEM 2871
Query: 4216 AGCSFKCHNSPNGPICSCPFGEQLVNKTK-CEPENECLDSSS-CSQRCKDEKHGFTCSCD 4389
C+ KC ++P C C G +L+ K CE +EC+++ CSQ+C++ F C C+
Sbjct: 2872 NQCAHKCIDTPTSYYCECNPGYRLLADGKACEDIDECVETPQVCSQQCQNTPGSFYCKCN 2931
Query: 4390 E-GYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLD--NWHTFGAIVENAIALAWD 4560
YE D+ TCK DN+ I+ N+ Y + +D N+ + N +AL D
Sbjct: 2932 HYWYERAADEHTCKRRDNIIPWIIFT---NKYYVRNMSIDALNYSLMHQDLINVVALDAD 2988
Query: 4561 SLTDRIYWSDIREKKILSAN-RNGTNATVFIADGLDITEGIALDWVGRNLYWVDSSLNTI 4737
+Y+ D+ K I A G + D L + EGIA+DW+GR LYW+D +
Sbjct: 2989 YGDQMLYFCDVTAKTIFRAPIAGGEKEAIIRHDSLGL-EGIAVDWIGRKLYWLDRHAKHL 3047
Query: 4738 EVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQNPCIERASMDGTD--RQII 4911
+VA L ++TLL ++ PR I V P G +++T W I + MDG++ R +
Sbjct: 3048 DVAELNGTNRKTLLT--GIADPRAIVVHPGTGYLYFTSWHLQAYIGKMGMDGSNFTRILT 3105
Query: 4912 VKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFE 5091
+ I WPN + +DY TDR+++AD+ LD+I F + +G R +VL S V H A+ IF+
Sbjct: 3106 WEDDIAWPNALTIDYFTDRIFWADAHLDYIAFADLEGHNRRKVL-SGTAVPHVFAITIFD 3164
Query: 5092 DMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTN--P 5265
D ++++D L+ + K+ +G +T + + A HP L+ + NNPC+ N
Sbjct: 3165 DFIFWTDWNLKAISRAEKF-SGYNLRVLRNTTHRPYDIHAYHP-LRQLPYNNPCNENNGG 3222
Query: 5266 CSHLCLLN--------------NKNTFTCKCPMGEKLDASGKKC 5355
CSHLCL++ ++ CKCP LD GK C
Sbjct: 3223 CSHLCLISPPASSYLLEGYGQPGVTSYKCKCPNQFVLDKDGKTC 3266
Score = 333 bits (855), Expect = 6e-89
Identities = 253/906 (27%), Positives = 382/906 (41%), Gaps = 53/906 (5%)
Frame = +1
Query: 9802 NECYEGISGCSQKC--------DDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLA 9957
N C GC C ++++G Y+C C G++LSSD +C + F + +
Sbjct: 576 NPCGNNNGGCQHMCIVTAASDQENRLG-YRCACDIGWRLSSDQRNCNLVQ----EFLMYS 630
Query: 9958 NKHYIRKISIDGNKYELAAQGFDNVVS-----------LDIDLTEKKAYLIDQGKLRLLR 10104
+ +I+ G + +GF + +S LD D ++ Y D +L+
Sbjct: 631 QQRFIK-----GRVLDPVMEGFSDAISPVVSRRARFVGLDYDAYDQYIYYSD-----VLQ 680
Query: 10105 VDLDEMDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLI 10284
+ + + E VL G EG+AVDWV + LY ++ ++ ++ V + +
Sbjct: 681 DVIYRVRQSGAGREVVLASQNEGVEGLAVDWVAKNLYYIDSRKGTLNVLSTRNVTYRRTL 740
Query: 10285 RDRIQQPKAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIA 10464
+++P+AIV+HP +GY+FF+EW I R DGS + +FK LGWPN +A
Sbjct: 741 LKNLKRPRAIVIHPNQGYIFFSEWDRPANISRAYTDGSNLI---VFK--NLSLGWPNGLA 795
Query: 10465 IDYFSDRLFWGDAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVL 10644
ID+ DRL+W DA L+ + + +G R + ++ H SM +++ ++Y DW L ++
Sbjct: 796 IDFAKDRLYWCDALLDHVQHSNLNGTDVRSVKSKLIRHPFSMAIYEQWMYITDWRLDAII 855
Query: 10645 RCDKWTGKNETILKKTVQLPNDLRIV------HPMRQPAYPNPCGDNNGGCSHLCLIGAG 10806
R K TG+ E+IL V+ P R+ ++ + +PC ++NGGC LC
Sbjct: 856 RLHKETGEQESIL---VRQPETNRLYGVKVYSRSIQTFLHDHPCFNDNGGCEKLCFAIPQ 912
Query: 10807 GN----GYT-----CSCPDQFVLLSDQKTCEPN---------CTER-QFACGGDDAKCIP 10929
N G T C CP + + +TC P+ C F C + +CI
Sbjct: 913 NNTNKYGITRLTKVCGCPYGERIQENGRTCAPDPEAEPPLEACPNTWDFTCA--NQRCIS 970
Query: 10930 KLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXXEQ 11109
W CDGE DC D SDE NCT+P
Sbjct: 971 HAWVCDGENDCLDNSDE--------------------RNCTKP----------------- 993
Query: 11110 NCDKACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEADTLCMSAERNCTAEEFRCNNN 11289
C P F+C +GRC+P F SDEA C + CTA +F C NN
Sbjct: 994 ----TCAPNQFQC-KSGRCVPMSFLCDSENDCGDYSDEAS--CPNV--TCTANQFACANN 1044
Query: 11290 KCIAKAWRXXXXXXXXXXXXETPECAQIECKKGWTRCSSSYRCIPNWAFCNGQDDCRDNS 11469
+CI W+ E C C C S CIP C+G +DC D
Sbjct: 1045 RCIPNTWKCDSENDCGDSSDEGDFCVAKTCSYFQFTCPRSGHCIPRSWVCDGDNDCFDQQ 1104
Query: 11470 DEDKQRCP--TCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSES 11643
DE CP TC +F CA C+ + CD +DC D SDE+ + ++
Sbjct: 1105 DE--MDCPPVTCLST-QFTCADQKMCVLDSYKCDGISDCNDGSDEVGCPSLAPDQCNTDK 1161
Query: 11644 EFRC-NDGKCIPGSKVCDGTIQCSDGLDE-SQCTLRRCLPGHRQCDDGTCIAEHKWCDRK 11817
+F+C + CIP S CDGT C D DE + C C PG +C + C+ + CD K
Sbjct: 1162 QFQCASSAICIPRSWYCDGTPDCPDRSDEPASCGQVGCQPGFFKCRNEKCVFKAYICDGK 1221
Query: 11818 KDCPNAADELHCEDVSRRTCSPFEFECANSVCIPRKFMXXXXXXXXXXSDETSSECRSAQ 11997
DC + +D ED C+ EF+C D +C +
Sbjct: 1222 DDCGDGSD----EDTELHACTAPEFKC----------------------DSQQWKCPNV- 1254
Query: 11998 CDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSFSEY--GDCSSDQFKCA 12171
+ +C+NI +C+ DC PN +DE + EY G CS+D +
Sbjct: 1255 -----------TNICVNITSVCDNKFDC-PNG-ADEGPACNFQECEYRGGYCSNDCIETP 1301
Query: 12172 NGK---CVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKHICTDVRDGFYC 12342
GK C +G C D ++ CE G C IC +++ G+YC
Sbjct: 1302 LGKQCTCPSGEELNKDGYTCEDLNE------------CEP---PGRCSQICVNIKRGYYC 1346
Query: 12343 HCRDGF 12360
+C +G+
Sbjct: 1347 NCVEGY 1352
Score = 296 bits (759), Expect = 8e-78
Identities = 287/1152 (24%), Positives = 432/1152 (36%), Gaps = 149/1152 (12%)
Frame = +1
Query: 2275 VECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHND-GLFSMSFDWISKQLYYVDNI 2451
++ D ++ D+ TI+R P G ++ H+ GL ++ DWI ++LY++D
Sbjct: 2985 LDADYGDQMLYFCDVTAKTIFRA-PIAGGEKEAIIRHDSLGLEGIAVDWIGRKLYWLDRH 3043
Query: 2452 RNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKGLLFYAEAMRPAAIYRCHI 2631
L+V ++ T R+ L+T + DP ++VVHP G L++ A I + +
Sbjct: 3044 AKHLDVAELNGTN--------RKTLLTGIADPRAIVVHPGTGYLYFTSWHLQAYIGKMGM 3095
Query: 2632 DGQNCQVIRN--TTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVKLDIDNPIP 2805
DG N I + P+ + ID+ +R+ W D L I+ D +G N K+ +P
Sbjct: 3096 DGSNFTRILTWEDDIAWPNALTIDYFTDRIFWADAHLDYIAFADLEGHNRRKVLSGTAVP 3155
Query: 2806 --VAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIP 2979
AITI +++I++ +I R K +G +++R I H P+
Sbjct: 3156 HVFAITIFDDFIFWTDWNLKAISRAEKFSGYNLRVLRNTTHRPYDI-------HAYHPLR 3208
Query: 2980 DDSREHPCRASQ--CTQLCFATPSES--------HPNELEAKCACRQGFMINKENN---- 3117
+PC + C+ LC +P S P KC C F+++K+
Sbjct: 3209 QLPYNNPCNENNGGCSHLCLISPPASSYLLEGYGQPGVTSYKCKCPNQFVLDKDGKTCTA 3268
Query: 3118 ------HSCQKDPAEKI---------EQLCSSNSTQ-------------FQCKNGRCIPK 3213
H C P EK E+ C S + FQC NG C P
Sbjct: 3269 NCTAGQHKCGP-PDEKCIPWYWKCDGEKDCKDGSDEPISCPARVCRPSVFQCANGNCRPS 3327
Query: 3214 EWKCDGENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXX 3393
CDG +DC D+SDE EC E KC++ +CI
Sbjct: 3328 VAVCDGADDCGDKSDE-------AHCSLECGELEFKCKSNGRCIHESWKCDGDAD----- 3375
Query: 3394 XXXVKYCKDG---------QKPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMC 3546
CKDG +P +F C N+RCI + W E MC
Sbjct: 3376 ------CKDGSDEDPAICHNRPCDPNTEFTCKNNRCIQKVWMCDSDNDCGDDSDEPAYMC 3429
Query: 3547 GNATCAANQFSC---ANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGR 3717
C C AN RCIP + CDG +DC DG+DE E CP + F+C N R
Sbjct: 3430 RQRNCTTGWQRCPGHANYRCIPKWLFCDGKDDCRDGSDELAENCPKCD-PEMDFKCTNNR 3488
Query: 3718 QCVPLR--NHXXXXXXXXXXXXXXXXAVTAESCTPDQFKCVSSGLCIPASWKXXXXXXXX 3891
CVP + C+ +F+C +G CI + W+
Sbjct: 3489 -CVPKQWLCDFADDCGDGSDEAETMCKNRYRECSESEFRC-DNGKCIASRWRCDSEDDCG 3546
Query: 3892 XXSDEPKFGCTSGRQCSSDQFKCGNGRCILNNWLCDGENDCGDGSDESSERGCKTSM-NA 4068
SDE GC C +D F+C +G CI + CDG DC D SDE GC
Sbjct: 3547 DNSDEN--GCQE-FVCKNDTFQCASGHCIASYLRCDGTRDCRDMSDEI---GCPPRYPGG 3600
Query: 4069 RKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEG-GRCARDLCSADRAGCSFKCHN- 4242
R CP C+N+ C+ L +CDG C G+DE CA C R F+C N
Sbjct: 3601 RYCPQSRFQCDNN--LCVYLSDICDGSDDCGDGSDENTNMCANFKCDTTR---RFQCANH 3655
Query: 4243 --------------------SPNGPICS-------------------------CPFGEQL 4287
N +C+ C F +
Sbjct: 3656 KCIAKYQLCDGIDNCGDGSDENNMTMCASRVRPCDAITEYTCANKKCIERTKLCDFADDC 3715
Query: 4288 VNKTK---CEPENECLDSS--SCSQRCKD-EKHGFTCSCDEGYELDVDKR---------- 4419
+ + C CLDS+ CS C + + G+ C+C GY + + R
Sbjct: 3716 GDSSDELGCHHNKPCLDSNKGGCSHYCHNITEGGYICACYPGYIISQNNRKHCEDINECV 3775
Query: 4420 -----TCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGAIVENAIAL--------AWD 4560
++ N+ T S R SD++ A+ N + L A+D
Sbjct: 3776 TGQHQCSQLCTNLNGT-YSCSCRQGFELSDNRSG---VCRAVDTNMMILFANGPGIRAYD 3831
Query: 4561 SLTDRIYWSDIREKKILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWV--DSSLNT 4734
+ EK++ + + + + VF DG +A+DW+ NLYW DSS T
Sbjct: 3832 PYDKQEIEVIANEKRVQALDFDPRSEYVFWIDGESGLTSLAMDWISGNLYWTEFDSSGTT 3891
Query: 4735 I---EVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTD----WGQNP--CIERASM 4887
+ + + D + R L+ + P I VDP G W D W + IE
Sbjct: 3892 LFGRVMVSKADGRYRRSLITVGLEIPTSIVVDPELGKAIWADHVLYWADSKLNTIESIEQ 3951
Query: 4888 DGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQH 5067
DG++R+II+K DS ++H
Sbjct: 3952 DGSNRKIILK--------------------GDS------------------------LKH 3967
Query: 5068 PHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNN 5247
P +L +FE+ +Y+ +R +L K+ G H + GV H + N
Sbjct: 3968 PISLDVFENSLYWITKRTGELIRQDKFGRGVPEIIVKHVPNSG-GVKVYHQQRYNISLRN 4026
Query: 5248 PCSTNPCSHLCL 5283
C + C+HLC+
Sbjct: 4027 LCHEDQCTHLCV 4038
Score = 274 bits (701), Expect = 4e-71
Identities = 209/741 (28%), Positives = 306/741 (41%), Gaps = 93/741 (12%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAE 336
C+ N+FRCN+G+CI W +P C + ++ C Y CI +
Sbjct: 2555 CSPNEFRCNNGRCIFKTWKCDHENDCRDGSDEEGCVYPPCAAGEFTCANYR-----CIPQ 2609
Query: 337 YQRCDNITDCADG--SDE--KDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDL 504
Q C+ I DC D SDE + CP +T N C C + CDG DC D
Sbjct: 2610 SQVCNGINDCKDNVTSDETHERCPRNTT--CPPNHLKCEKTNICVEPYWLCDGDNDCGDN 2667
Query: 505 SDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPD---TCEFKKCTA 675
SDE T C Q FRC + +CI +W CDG DC DGSDEP E + C
Sbjct: 2668 SDENPLHCAQRT-CPQSSFRCPNH-RCIPATWYCDGDDDCLDGSDEPPGYCQSEGRTCFG 2725
Query: 676 NEFQCKNKRCQPRKFRCDYYDDCGDNSDEDE---CGEYRCP------------------- 789
+ F C N C PR + CD +DC D SDEDE C + +C
Sbjct: 2726 DLFTCDNGNCIPRIYICDGDNDCLDYSDEDERHQCNDRKCDEETEFTCTANKVWHRAQCI 2785
Query: 790 PGKWNCPG-----------------------------------------TGHCIDQLKLC 846
P KW C G G CIDQ +C
Sbjct: 2786 PKKWLCDGDPDCVDGADENDDCGDHSDEDGCPPKMKNMTCSNPKEFMCANGICIDQQLVC 2845
Query: 847 DGSKDCADGADEQ-QCSQNLCPSLG---CQAGCHPSPHGGECTCPSGYKLDDRFHRTCSD 1014
+ DCAD +DE C+ + C + C C +P C C GY+L + C D
Sbjct: 2846 NKEPDCADESDEPAHCNVDECAMVEMNQCAHKCIDTPTSYYCECNPGYRLLAD-GKACED 2904
Query: 1015 INECAEFGY-CDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKL 1191
I+EC E C Q C N F C C + + K + + + N
Sbjct: 2905 IDECVETPQVCSQQCQNTPGSFYCKCNHYWYERAADEHTCKRRDNIIPWIIFTNK----- 2959
Query: 1192 FVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADV--DD 1365
+ R + LN +++ + + +D DYGD+ +++ D A + F A + +
Sbjct: 2960 YYVRNMSIDALNYSLMHQDLINVVA------LDADYGDQMLYFCDVTAKTIFRAPIAGGE 3013
Query: 1366 EGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTL 1545
+ I + L L+ + AVDWI LY ++ ++ +DV+ +G R LL G+
Sbjct: 3014 KEAIIRHDSLGLEGI------AVDWIGRKLYWLDRHAKHLDVAELNGTNRKTLLT-GIAD 3066
Query: 1546 PLDIALDPLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHTHQV--SGIVVDITAKRVY 1710
P I + P G ++FT+ Q + MDG+N ++ + + +D R++
Sbjct: 3067 PRAIVVHPGTGYLYFTSWHLQAYIGKMGMDGSNFTRILTWEDDIAWPNALTIDYFTDRIF 3126
Query: 1711 WVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFGS 1890
W D +D + D +G++RR V G VPH F + +FD +++WTDW + + EKF
Sbjct: 3127 WADAHLDYIAFADLEGHNRRKVLSG-TAVPHVFAITIFDDFIFWTDWNLKAISRAEKFSG 3185
Query: 1891 DTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPC--TNADCEGMCILSKDN 2064
+ NT + P I AYHP+ Q + NPC N C +C++S
Sbjct: 3186 YNLRVLRNTTHR--PYDIHAYHPLRQ----------LPYNNPCNENNGGCSHLCLISPPA 3233
Query: 2065 G-----GFG----VGYKCACP 2100
G+G YKC CP
Sbjct: 3234 SSYLLEGYGQPGVTSYKCKCP 3254
Score = 272 bits (696), Expect = 2e-70
Identities = 221/783 (28%), Positives = 332/783 (42%), Gaps = 17/783 (2%)
Frame = +1
Query: 11269 EFRCNNNKCIAKAWRXXXXXXXXXXXXETPECAQIECKKGWTRCSSSYRCIPNWAFCNGQ 11448
+F C N +CI+ AW E C + C +C S RC+P C+ +
Sbjct: 960 DFTCANQRCISHAWVCDGENDCLDNSDER-NCTKPTCAPNQFQCKSG-RCVPMSFLCDSE 1017
Query: 11449 DDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTR 11628
+DC D SDE TC +F CA + +CIP W CD+ENDCGD+SDE D T
Sbjct: 1018 NDCGDYSDEASCPNVTCT-ANQFACANN-RCIPNTWKCDSENDCGDSSDEGDFCVAKT-- 1073
Query: 11629 PCSESEFRC-NDGKCIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQC-DDGTCIAEHK 11802
CS +F C G CIP S VCDG C D DE C CL C D C+ +
Sbjct: 1074 -CSYFQFTCPRSGHCIPRSWVCDGDNDCFDQQDEMDCPPVTCLSTQFTCADQKMCVLDSY 1132
Query: 11803 WCDRKKDCPNAADELHCEDVSRRTCSPF-EFECANS-VCIPRKFMXXXXXXXXXXSDETS 11976
CD DC + +DE+ C ++ C+ +F+CA+S +CIPR + SDE +
Sbjct: 1133 KCDGISDCNDGSDEVGCPSLAPDQCNTDKQFQCASSAICIPRSWYCDGTPDCPDRSDEPA 1192
Query: 11977 SECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSFSEYGDCSSD 12156
S C C P F+C + + C+ +C+G +DCG D L C++ E+ C S
Sbjct: 1193 S-CGQVGCQPGF-FKCRNEK-CVFKAYICDGKDDCGDGSDEDTELHACTA-PEF-KCDSQ 1247
Query: 12157 QFKCAN--GKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKHICTDVRD 12330
Q+KC N CVN T CD K DC + +DE CE G G C + C +
Sbjct: 1248 QWKCPNVTNICVNITSVCDNKFDCPNGADEGPACNF---QECEYRG--GYCSNDCIETPL 1302
Query: 12331 GFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGSYLCRCHEDYENNVVVGSM 12510
G C C G + C D++EC C+Q+C+N K Y C C V G
Sbjct: 1303 GKQCTCPSGEELNKDG-YTCEDLNECEPPGRCSQICVNIKRGYYCNC--------VEGYT 1353
Query: 12511 TGKD---CRA-KGDAANVMIGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXXXXPRK 12678
KD C+A A ++I +++ L R
Sbjct: 1354 LEKDKHTCKAFNHSVAFLIISNRHTILVADLQDQALERVPINVENVVATASNMHTGT--- 1410
Query: 12679 ELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAVSE 12858
++W D + I R + G+ + +D +A D+ NL+
Sbjct: 1411 --IFWSDMKLKKISR--LDRGSDPEDVISTGLDLVE------GLAYDWIGHNLYW----- 1455
Query: 12859 NIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGR-- 13032
+++ L T I V G +V ++ QP + PS G
Sbjct: 1456 -LDSKLNT-----------------IEVAKETGSNRMILVKENITQPRGMCLDPSPGARW 1497
Query: 13033 ICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVN 13212
+ ++D G + +IE MDGT+R I+ ++ P +A+D RIY+ D K +D
Sbjct: 1498 LFWTDWGENPRIERIGMDGTNRSTIINTKIYWPNGLALDIA-NKRIYFADSKLDFIDTCL 1556
Query: 13213 IDGSERTTVVHDRHI---PYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDG 13383
DGS+R V+ H P+++ +FE+ +YW R+ + KF +V++ +
Sbjct: 1557 YDGSKRIQVLASSHYLLHPHSLTLFEDTMYWTDRQLNRVLSAHKFYGVNQTVVSHLISQP 1616
Query: 13384 HTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPS--TGFACLCPDGIVPQLDGSCATQHV 13557
++ V + T + C + C HLC+ P+ G+ C C G +G C + +
Sbjct: 1617 LSIHVHHPVLQPI--TANPCANSTCDHLCLLSPTKPQGYTCKCQVGF-RLFNGQCLEEEI 1673
Query: 13558 EAL 13566
L
Sbjct: 1674 PYL 1676
Score = 247 bits (631), Expect = 5e-63
Identities = 192/664 (28%), Positives = 280/664 (41%), Gaps = 35/664 (5%)
Frame = +1
Query: 163 ENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXP----HPGCKSDQWQCDTYTWHSVSCI 330
E DF+C + +C+ +W + C +++CD + CI
Sbjct: 3479 EMDFKCTNNRCVPKQWLCDFADDCGDGSDEAETMCKNRYRECSESEFRCD-----NGKCI 3533
Query: 331 AEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSD 510
A RCD+ DC D SDE C + F CA G C +CDG DCRD+SD
Sbjct: 3534 ASRWRCDSEDDCGDNSDENGCQEFVC---KNDTFQCASGH-CIASYLRCDGTRDCRDMSD 3589
Query: 511 EKDSCSR--NHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDE-PDTCEFKKC-TAN 678
E R C Q +F+C D C+ S +CDGS DC DGSDE + C KC T
Sbjct: 3590 EIGCPPRYPGGRYCPQSRFQC-DNNLCVYLSDICDGSDDCGDGSDENTNMCANFKCDTTR 3648
Query: 679 EFQCKNKRCQPRKFRCDYYDDCGDNSDE-------------DECGEYRCPPGKWNCPGTG 819
FQC N +C + CD D+CGD SDE D EY C K
Sbjct: 3649 RFQCANHKCIAKYQLCDGIDNCGDGSDENNMTMCASRVRPCDAITEYTCANKK------- 3701
Query: 820 HCIDQLKLCDGSKDCADGADEQQCSQNLCPSL-----GCQAGCHPSPHGGE-CTCPSGYK 981
CI++ KLCD + DC D +DE C N P L GC CH GG C C GY
Sbjct: 3702 -CIERTKLCDFADDCGDSSDELGCHHNK-PCLDSNKGGCSHYCHNITEGGYICACYPGYI 3759
Query: 982 LDDRFHRTCSDINECAEFGY-CDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGY 1158
+ + C DINEC + C QLC N ++CSC F L DN + G
Sbjct: 3760 ISQNNRKHCEDINECVTGQHQCSQLCTNLNGTYSCSC-RQGFEL-------SDNRS--GV 3809
Query: 1159 CVSNNADKMKLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAH 1338
C + + + M LF A G+ +P + +E++ +A+ + + +DFD +FW
Sbjct: 3810 CRAVDTNMMILF-ANGPGIRAYDPYD-KQEIEVIANEKRVQALDFDPRSEYVFW------ 3861
Query: 1339 SAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSR------RIDVSSY 1500
+D E ++ LA+DWI+ LY E S R+ VS
Sbjct: 3862 ------IDGESGLTS--------------LAMDWISGNLYWTEFDSSGTTLFGRVMVSKA 3901
Query: 1501 DGERRTVLLADGLTLPLDIALDPLRGEMFFTNQLKLEAAAMDGTNRRTLVNTHTHQVSGI 1680
DG R L+ GL +P I +DP G+ + + +
Sbjct: 3902 DGRYRRSLITVGLEIPTSIVVDPELGKAIWADHV-------------------------- 3935
Query: 1681 VVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRL 1860
+YW D K++ +ESI+ G++R+I+ +G + + HP L +F+ LYW
Sbjct: 3936 --------LYWADSKLNTIESIEQDGSNRKIILKG-DSLKHPISLDVFENSLYWITKRTG 3986
Query: 1861 GVIQVEKFGSDT-KLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCE 2037
+I+ +KFG +++ + N+ G+ YH + + + N C C
Sbjct: 3987 ELIRQDKFGRGVPEIIVKHVPNS---GGVKVYH---------QQRYNISLRNLCHEDQCT 4034
Query: 2038 GMCI 2049
+C+
Sbjct: 4035 HLCV 4038
Score = 239 bits (610), Expect = 1e-60
Identities = 174/628 (27%), Positives = 271/628 (42%), Gaps = 73/628 (11%)
Frame = +1
Query: 9205 CIPRAWLCDGDVTCAGGEDESTELCKTEKKECNKGEFRC-----SNQHCIHSTWECDGDN 9369
CIP +C+ C EDE + C G+ C + +CI CD
Sbjct: 29 CIPATLVCNYQKDCESAEDEFQSCTPPD---CEAGQITCGQYIFNKTYCIPPHQRCDMTV 85
Query: 9370 DCLDGSDE----------------HANCT------------------------------- 9408
DC+DG+DE H N
Sbjct: 86 DCVDGTDEAGCRNVNRMIFDVEVQHQNFVSQKRRNAMVIWIVEMVVMRRNVRIIRNQLVD 145
Query: 9409 YSSCQPDFFQCANHKCVPNSWKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTS 9588
+ C D F+CAN C+P S+ CDG DC DGSDEK C S C +F C
Sbjct: 146 FQQCTMDQFRCANSLCIPRSYVCDGYKDCHDGSDEKSCTTTS--------CPQNKFVCPR 197
Query: 9589 GE------CIDDAKVCDRNFDCTDRSDESSLCFIDEC-SLAEKPLCEQKCMDMKIGYKCD 9747
G CID +++CD DC D++DE + C C SLA C KC G C
Sbjct: 198 GTTDGKPLCIDRSQICDGKTDCEDKADEEATCSSVICTSLA----CRYKCRASPTGGVCY 253
Query: 9748 CFEGFAIDISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTE 9927
C G+ + +D +C + +EC E C Q C + GSY C C G+ L + +
Sbjct: 254 CPAGWIL-ANDSTTCIDRDECSEW-GFCEQLCKNTEGSYTCSCAPGFILQGLNKCRAQQH 311
Query: 9928 MEPEPFFLLANKHYIRKISIDGNKYEL-----AAQGFDNVVSLDIDLTEKKAYLIDQGKL 10092
+ L+A + + ++S +G + +A G D + S D L+ +
Sbjct: 312 PGVKLELLVAQEKAVWRMSSNGEDRTIVANTTSASGVDYLYSRD---------LLFWSDV 362
Query: 10093 RLLRVDLDEMDSP-LSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRF 10269
+ +V + ++ SS + + +G IAVDW+G KLY+++ + I V ELDGR+
Sbjct: 363 KTKKVHSEPLNGEGSSSRVAIYLTSSWGPVSIAVDWIGEKLYVVDSVVQKIDVLELDGRY 422
Query: 10270 CKTLIRDRIQQPKAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGW 10449
+ + P I + P G +F + + R +DG+ + PI A + +
Sbjct: 423 HGIALSSNLTNPTDIGLDPTVGLMFIAD---SKRVLRANMDGTVDF--PIVFEAAYKV-- 475
Query: 10450 PNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHIPAQRTSHVSS---MVVFDDYLYWA 10620
+ IA+D + R+FW D+ L+ I D+ GR + R +H S + +F++ +YW
Sbjct: 476 -SGIAVDVIARRIFWCDSQLDYIETADY--LGRNRVMVLRGTHTPSPTRLTLFENRIYWT 532
Query: 10621 DWNLREVLRCDKWTGKNETILKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIG 10800
D + ++ DK G ++ ++ +HP+ QP NPCG+NNGGC H+C++
Sbjct: 533 DGTKQAIMSVDKTEGDYSIRTIYKMRDAKAIKTLHPLTQPMVSNPCGNNNGGCQHMCIVT 592
Query: 10801 AGGN-----GYTCSCPDQFVLLSDQKTC 10869
A + GY C+C + L SDQ+ C
Sbjct: 593 AASDQENRLGYRCACDIGWRLSSDQRNC 620
Score = 168 bits (425), Expect = 4e-39
Identities = 161/657 (24%), Positives = 259/657 (38%), Gaps = 29/657 (4%)
Frame = +1
Query: 11632 CSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQ-CTLRRCLPGHRQC-----DDGTCIA 11793
C + FRC DG CIP + VC+ C DE Q CT C G C + CI
Sbjct: 17 CGVNSFRCLDGTCIPATLVCNYQKDCESAEDEFQSCTPPDCEAGQITCGQYIFNKTYCIP 76
Query: 11794 EHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFECANSVCIPRKFMXXXXXXXXXXSDET 11973
H+ CD DC + DE C +V+R E + N V R+
Sbjct: 77 PHQRCDMTVDCVDGTDEAGCRNVNRMIFD-VEVQHQNFVSQKRRNAMVIWIVEMVVMRRN 135
Query: 11974 SSECRSA-----QCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSFSEY 12138
R+ QC +FRCA+S LC+ +C+G+ DC +D SDE C++ S
Sbjct: 136 VRIIRNQLVDFQQCTMD-QFRCANS-LCIPRSYVCDGYKDC--HDGSDE--KSCTTTS-- 187
Query: 12139 GDCSSDQFKCANGK------CVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGG 12300
C ++F C G C++ + CD K DC D +DE T +
Sbjct: 188 --CPQNKFVCPRGTTDGKPLCIDRSQICDGKTDCEDKADEEA-------TCSSVICTSLA 238
Query: 12301 CKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGSYLCRCHED 12480
C++ C G C+C G+ S CID DEC+ C QLC NT+GSY C C
Sbjct: 239 CRYKCRASPTGGVCYCPAGWILANDSTT-CIDRDECSEWGFCEQLCKNTEGSYTCSCAPG 297
Query: 12481 YENNVVVGSMTGKDCRAK---GDAANVMIGADDSLVQLSLHGSGTNRHXXXXXXXXXXXX 12651
+ ++ G CRA+ G +++ + ++ ++S +G
Sbjct: 298 F---ILQGL---NKCRAQQHPGVKLELLVAQEKAVWRMSSNGEDRT------IVANTTSA 345
Query: 12652 XXXXXXPRKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTAIAVDYTTG 12831
++L++W D + ++ + NG S + + P +IAVD+
Sbjct: 346 SGVDYLYSRDLLFWSDVKTKKVHSEPL-NGEGSSSRVAI---YLTSSWGPVSIAVDWIGE 401
Query: 12832 NLFIA-AVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTAL 13008
L++ +V + I+ V DGRY ++ +L PT +
Sbjct: 402 KLYVVDSVVQKID------------------------VLELDGRYHGIALSSNLTNPTDI 437
Query: 13009 ITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPK 13188
P+ G + +D+ ++ A+MDGT IV + + + +A+D RI+W D +
Sbjct: 438 GLDPTVGLMFIADS---KRVLRANMDGTVDFPIVFEAAYKVSGIAVDV-IARRIFWCDSQ 493
Query: 13189 YRRVDAVNIDGSERTTVVHDRHI--PYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVL 13362
++ + G R V+ H P + +FEN IYW + + DK
Sbjct: 494 LDYIETADYLGRNRVMVLRGTHTPSPTRLTLFENRIYWTDGTKQAIMSVDKTEGDYSIRT 553
Query: 13363 ASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPST------GFACLCPDG 13515
+ D ++ + G C H+C+ ++ G+ C C G
Sbjct: 554 IYKMRDAKAIKTLHPLTQPMVSNPCGNNNGGCQHMCIVTAASDQENRLGYRCACDIG 610
Score = 167 bits (424), Expect = 5e-39
Identities = 181/731 (24%), Positives = 270/731 (36%), Gaps = 42/731 (5%)
Frame = +1
Query: 9817 GISGCSQKC----DDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKIS 9984
G +GC Q C + +KC C G +L+ D +C+ + + A + IR I
Sbjct: 2273 GNAGCKQLCFAMPKENSVPFKCECAVG-KLAIDGKNCENVN----EYLVFATRTEIRAIG 2327
Query: 9985 IDGNKYELAAQ---GFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVL 10155
+D + NVV +D D +KK L+ ++ + ++P SS L
Sbjct: 2328 LDPQNTTIPFNPIGNLTNVVGVDFDYQDKK--LLFTQIRPWAKIAWMQAENPSSSEIHTL 2385
Query: 10156 RHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKG 10335
EGI+ DW +K+Y + SI +L+G ++ R+ +P+AIVV P G
Sbjct: 2386 ISKGINPEGISYDWTQKKVYWTDSSNNSIYAMDLNGS--NLVMIARVDRPRAIVVDPCNG 2443
Query: 10336 YLFFTEWSLQPYIGRI---ALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAH 10506
L+FT+W G+I + GS + + + DL P+ +AIDY D
Sbjct: 2444 SLYFTDWGRFGTSGKIFKTTMAGSLKK-----AVIDKDLSQPSGLAIDYEDPECKCDDNS 2498
Query: 10507 --LNEIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETI 10680
+NE R +P T S + W C + ++
Sbjct: 2499 RLVNE---------DRMCVPKNVTCDSSKFACRNGRCISRMWACDGDDDCGDGSDEDTNY 2549
Query: 10681 LKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQ 10860
PN+ R NNG C+ + C D SD+
Sbjct: 2550 CSYHSCSPNEFRC---------------NNG----RCIFKTWKCDHENDCRDG----SDE 2586
Query: 10861 KTC-EPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDG--SDEPGESICGQRICPVGEFQ 11031
+ C P C +F C + +CIP+ C+G DC+D SDE E CP +
Sbjct: 2587 EGCVYPPCAAGEFTCA--NYRCIPQSQVCNGINDCKDNVTSDETHERCPRNTTCPPNHLK 2644
Query: 11032 CTNHN-CTRPFQIXXXXXXXXXXXXEQ--NC-DKACDPWMFKCAATGRCIPRRFTXXXXX 11199
C N C P+ + E +C + C F+C RCIP +
Sbjct: 2645 CEKTNICVEPYWLCDGDNDCGDNSDENPLHCAQRTCPQSSFRC-PNHRCIPATWYCDGDD 2703
Query: 11200 XXXXRSDEADTLCMSAERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXETPECAQIEC 11379
SDE C S R C + F C+N CI + +
Sbjct: 2704 DCLDGSDEPPGYCQSEGRTCFGDLFTCDNGNCIPRIY----------------------- 2740
Query: 11380 KKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDED-KQRC--PTCDDVGEFRCATS-----G 11535
C+G +DC D SDED + +C CD+ EF C +
Sbjct: 2741 ------------------ICDGDNDCLDYSDEDERHQCNDRKCDEETEFTCTANKVWHRA 2782
Query: 11536 KCIPRRWMCDTENDCGDNSDELDASCGG-----------TTRPCSE-SEFRCNDGKCIPG 11679
+CIP++W+CD + DC D +DE D CG CS EF C +G CI
Sbjct: 2783 QCIPKKWLCDGDPDCVDGADEND-DCGDHSDEDGCPPKMKNMTCSNPKEFMCANGICIDQ 2841
Query: 11680 SKVCDGTIQCSDGLDE-SQCTLRRCLPGHRQCDDGTCI--AEHKWCDRKKDCPNAADELH 11850
VC+ C+D DE + C + C CI +C+ AD
Sbjct: 2842 QLVCNKEPDCADESDEPAHCNVDECAMVEMNQCAHKCIDTPTSYYCECNPGYRLLADGKA 2901
Query: 11851 CEDVSRRTCSP 11883
CED+ +P
Sbjct: 2902 CEDIDECVETP 2912
Score = 156 bits (395), Expect = 1e-35
Identities = 111/338 (32%), Positives = 152/338 (44%), Gaps = 34/338 (10%)
Frame = +1
Query: 157 CNENDFRC-NDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDT-YTWHSVSCI 330
C E +F+C ++G+CI W C + +T +T + CI
Sbjct: 3350 CGELEFKCKSNGRCIHESWKCDGDADCKDGSDEDPAI---CHNRPCDPNTEFTCKNNRCI 3406
Query: 331 AEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQ---------CFDVSKKCDG 483
+ CD+ DC D SDE PA C +N C G Q C CDG
Sbjct: 3407 QKVWMCDSDNDCGDDSDE---PAYM--CRQRN---CTTGWQRCPGHANYRCIPKWLFCDG 3458
Query: 484 KYDCRDLSDEKDSCSRNHTACF-QYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTC-- 654
K DCRD SDE + N C + F+C + +C+ K W+CD + DC DGSDE +T
Sbjct: 3459 KDDCRDGSDE---LAENCPKCDPEMDFKCTNN-RCVPKQWLCDFADDCGDGSDEAETMCK 3514
Query: 655 -EFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCID 831
+++C+ +EF+C N +C ++RCD DDCGDNSDE+ C E+ C + C +GHCI
Sbjct: 3515 NRYRECSESEFRCDNGKCIASRWRCDSEDDCGDNSDENGCQEFVCKNDTFQC-ASGHCIA 3573
Query: 832 QLKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCS 1011
CDG++DC D +DE GC P GG S ++ D+ S
Sbjct: 3574 SYLRCDGTRDCRDMSDE--------------IGCPPRYPGGRYCPQSRFQCDNNLCVYLS 3619
Query: 1012 DI---------------NECAEFGYCDQL----CANHR 1068
DI N CA F CD CANH+
Sbjct: 3620 DICDGSDDCGDGSDENTNMCANF-KCDTTRRFQCANHK 3656
Score = 154 bits (388), Expect = 8e-35
Identities = 90/210 (42%), Positives = 108/210 (50%), Gaps = 7/210 (3%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDEK-DCPASTVDCSSQNVFMCADGR 450
C + Q +C CI Y +CD DC DGSDE CPA S VF CA+G
Sbjct: 3270 CTAGQHKCGP---PDEKCIPWYWKCDGEKDCKDGSDEPISCPARVCRPS---VFQCANGN 3323
Query: 451 QCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCAD 630
C CDG DC D SDE CS C + +F+C +CI +SW CDG DC D
Sbjct: 3324 -CRPSVAVCDGADDCGDKSDEAH-CSLE---CGELEFKCKSNGRCIHESWKCDGDADCKD 3378
Query: 631 GSDE-PDTCEFKKCTAN-EFQCKNKRCQPRKFRCDYYDDCGDNSDEDE--CGEYRCPPGK 798
GSDE P C + C N EF CKN RC + + CD +DCGD+SDE C + C G
Sbjct: 3379 GSDEDPAICHNRPCDPNTEFTCKNNRCIQKVWMCDSDNDCGDDSDEPAYMCRQRNCTTGW 3438
Query: 799 WNCPGTGH--CIDQLKLCDGSKDCADGADE 882
CPG + CI + CDG DC DG+DE
Sbjct: 3439 QRCPGHANYRCIPKWLFCDGKDDCRDGSDE 3468
Score = 113 bits (282), Expect = 2e-22
Identities = 64/178 (35%), Positives = 85/178 (46%), Gaps = 1/178 (0%)
Frame = +1
Query: 502 LSDEKDSCSRNHTACFQYQFRCADKTQ-CIQKSWVCDGSKDCADGSDEPDTCEFKKCTAN 678
L + +C+ N TA Q +C + CI W CDG KDC DGSDEP +C + C +
Sbjct: 3259 LDKDGKTCTANCTAG---QHKCGPPDEKCIPWYWKCDGEKDCKDGSDEPISCPARVCRPS 3315
Query: 679 EFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSK 858
FQC N C+P CD DDCGD SDE C C ++ C G CI + CDG
Sbjct: 3316 VFQCANGNCRPSVAVCDGADDCGDKSDEAHC-SLECGELEFKCKSNGRCIHESWKCDGDA 3374
Query: 859 DCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAE 1032
DC DG+DE P++ C P+ E TC + + + C N+C +
Sbjct: 3375 DCKDGSDED-------PAICHNRPCDPNT---EFTCKNNRCIQKVW--MCDSDNDCGD 3420
Score = 100 bits (249), Expect = 1e-18
Identities = 66/241 (27%), Positives = 110/241 (45%), Gaps = 7/241 (2%)
Frame = +1
Query: 10171 GTEGIAVDWVGRKLYMLN--RQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLF 10344
G G+A+DWV +Y N + + VC+LDG K L++ P+ + V+P K YL+
Sbjct: 2076 GIRGLAIDWVAENMYFTNVFPHDNYVEVCKLDGSNRKVLVKKTTDSPRELAVNPIKKYLY 2135
Query: 10345 FTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGF 10524
+ ++ P +G+ LDGS + + + P I ID + ++W D+ + I
Sbjct: 2136 WIDYGQYPRLGKAYLDGSNWM-----PIVTSGISTPRDITIDPITHDVYWVDSKQDTIQK 2190
Query: 10525 MDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETI-LKKTVQL 10701
+ + G G R I + + + ++ + +YW D NL V + K N ++ ++ +
Sbjct: 2191 VSYTG-GNRQIIRRNLPNPMGVAIYGNDVYWVDRNLGIVFKASKQNDNNSSVTVRSNLPK 2249
Query: 10702 PNDLRIVHPMRQPAYP-NPCGDN-NGGCSHLCLIGAGGNG--YTCSCPDQFVLLSDQKTC 10869
D+ + QP P NPC + N GC LC N + C C L D K C
Sbjct: 2250 LRDIVMFDQNSQPPDPTNPCSSSGNAGCKQLCFAMPKENSVPFKCECA-VGKLAIDGKNC 2308
Query: 10870 E 10872
E
Sbjct: 2309 E 2309
Score = 89.4 bits (220), Expect = 2e-15
Identities = 76/300 (25%), Positives = 134/300 (44%), Gaps = 5/300 (1%)
Frame = +1
Query: 6466 LSITGVDYDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINY 6645
+++ +D DY + +Y + + K I I A+IR SL ++ +A+DWI
Sbjct: 2980 INVVALDADYGDQMLYFCDVTA--KTIFRAPIAGGEKEAIIRHD--SLGLEGIAVDWIGR 3035
Query: 6646 NMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQR 6825
+Y+++ A+ +++V++L+GT RK LLT + P +I V P + YLY+ + I +
Sbjct: 3036 KLYWLDRHAK--HLDVAELNGTNRKTLLTGIAD-PRAIVVHPGTGYLYFTSWHLQAYIGK 3092
Query: 6826 SFLDGSR--REVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPELVRSDI 6999
+DGS R + IA P L +D + I+W+DA +D I G V S
Sbjct: 3093 MGMDGSNFTRILTWEDDIAWPNALTIDYFTDRIFWADAHLDYIAFADLEGHNRRKVLSGT 3152
Query: 7000 A--SAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSN 7173
A + + ++WTD L+ + RA +L TT D+ +
Sbjct: 3153 AVPHVFAITIFDDFIFWTDWNLKAISRAEKFSGYNLRVLRNTTHRPY-----DIHAYHPL 3207
Query: 7174 NQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTC-SCARGVLKGRTCEEPDTYIMFSDG 7350
Q ++PC N C+ LC +P + + + C+ P+ +++ DG
Sbjct: 3208 RQLPYNNPC----NENNGGCSHLCLISPPASSYLLEGYGQPGVTSYKCKCPNQFVLDKDG 3263
Score = 89.4 bits (220), Expect = 2e-15
Identities = 73/280 (26%), Positives = 100/280 (35%), Gaps = 70/280 (25%)
Frame = +1
Query: 8389 NFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLC-----TNRRCIDSAK 8553
+F+C DG+CI C+ + DC A DE + C C C CI +
Sbjct: 21 SFRCLDGTCIPATLVCNYQKDCESAEDEFQS-CTPPDCEAGQITCGQYIFNKTYCIPPHQ 79
Query: 8554 KCNHIDDCGDGSDELDCPSA---------------------------------------- 8613
+C+ DC DG+DE C +
Sbjct: 80 RCDMTVDCVDGTDEAGCRNVNRMIFDVEVQHQNFVSQKRRNAMVIWIVEMVVMRRNVRII 139
Query: 8614 -------VACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPGLPIDCRGVKV 8772
C F C+N CI ++ VCDG+ DCHD SDE T P + K
Sbjct: 140 RNQLVDFQQCTMDQFRCANSLCIPRSYVCDGYKDCHDG--SDEKSCTTTSCPQN----KF 193
Query: 8773 RCPNTN-----ICIQPADLCDGYDDCGDKADE----NQLFCMNQQCAQHYVRCPSGRC-- 8919
CP +CI + +CDG DC DKADE + + C + C P+G
Sbjct: 194 VCPRGTTDGKPLCIDRSQICDGKTDCEDKADEEATCSSVICTSLACRYKCRASPTGGVCY 253
Query: 8920 IPETW-------QCDGDNDCSDGWDETHTNCTDTAGKKIC 9018
P W C ++CS+ W C +T G C
Sbjct: 254 CPAGWILANDSTTCIDRDECSE-WGFCEQLCKNTEGSYTC 292
Score = 87.4 bits (215), Expect = 9e-15
Identities = 94/379 (24%), Positives = 162/379 (41%), Gaps = 28/379 (7%)
Frame = +1
Query: 9823 SGCSQKC---DDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDG 9993
S C C K Y C C G++L + C E+ P+ ++ I +S+
Sbjct: 1637 STCDHLCLLSPTKPQGYTCKCQVGFRLFNGQ--CLEEEI---PYLMVLRGSQIVDVSLLP 1691
Query: 9994 NK----YELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDE----MDSPLSSYET 10149
Y G ++ +D D EK Y + + D DE +P +
Sbjct: 1692 RSIKTGYITPVVGVESGKFIDYDRKEKMIYWLQT------KDDDDENGTIYTTPYNGGNR 1745
Query: 10150 VLRHNVYGTEGI-------AVDWVGRKLYMLNRQERSIRVCELDGRF-CKTLI------R 10287
N G GI A DW+GR L++ N+ +I ++DG+ +T++ +
Sbjct: 1746 TEFPNASGESGIVGAPSAMAFDWLGRNLFIGNKYASNIEAIKIDGKTKYRTIVLANDGNK 1805
Query: 10288 DRIQQPKAIVVHPGKGYLFFTE---WSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNA 10458
+ +PKA+ V P +G++F+ + + + IGR+ +DG+ +PI + ++ P A
Sbjct: 1806 TSVAKPKAMCVDPLEGHIFWVDGGSFGIPTKIGRVNMDGT----NPI--ILVDNVERPEA 1859
Query: 10459 IAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLRE 10638
I ID + +++ + I + DG R I +Q + ++ V D LY D +
Sbjct: 1860 ITIDIPTKTIYFSSLYPALIMALSTDGQNLRTIVSQNIALPKALAVHDSRLYLLDPLYDK 1919
Query: 10639 VLRCDKWTGKNETILKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGY 10818
+ R D G N T + L I ++ +PC NNG C +CL +GG
Sbjct: 1920 IERVDLPDGGNPTTIIDNDSELKTLTIY--KKRITGDHPCFINNGDCEQICLPASGGT-R 1976
Query: 10819 TCSCPDQFVLLSDQKTCEP 10875
C+C ++ +SD +CEP
Sbjct: 1977 VCACGMEYRKVSD-TSCEP 1994
Score = 87.0 bits (214), Expect = 1e-14
Identities = 75/280 (26%), Positives = 123/280 (43%), Gaps = 16/280 (5%)
Frame = +1
Query: 6250 CHINNGNCDHICIPLMFAQRTCTCANGYVKDGQTS--CKLFDESFVIV-ATKTKVIGY-P 6417
C C +C L +C+C G+ S C+ D + +I+ A + Y P
Sbjct: 3774 CVTGQHQCSQLCTNLN-GTYSCSCRQGFELSDNRSGVCRAVDTNMMILFANGPGIRAYDP 3832
Query: 6418 IDETQSKGVAMEPIGGLSITGVDYDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDS 6597
D+ + + +A E + +D+D S+ ++ + GES
Sbjct: 3833 YDKQEIEVIANEK----RVQALDFDPRSEYVFWID-------------GESG-------- 3867
Query: 6598 IGSLTIKSLAIDWINYNMYFINHDAERTN----IEVSKLDGTYRKILLTTKTETPSSIAV 6765
+ SLA+DWI+ N+Y+ D+ T + VSK DG YR+ L+T E P+SI V
Sbjct: 3868 -----LTSLAMDWISGNLYWTEFDSSGTTLFGRVMVSKADGRYRRSLITVGLEIPTSIVV 3922
Query: 6766 DP-------VSRYLYWADQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYW 6924
DP LYWAD + TI+ DGS R++I+ G + + +DV +YW
Sbjct: 3923 DPELGKAIWADHVLYWAD-SKLNTIESIEQDGSNRKIIL-KGDSLKHPISLDVFENSLYW 3980
Query: 6925 SDAKMDGIYRVRSTG-GTPELVRSDIASAAGVALHGQNMY 7041
+ + R G G PE++ + ++ GV ++ Q Y
Sbjct: 3981 ITKRTGELIRQDKFGRGVPEIIVKHVPNSGGVKVYHQQRY 4020
Score = 72.0 bits (175), Expect = 4e-10
Identities = 74/291 (25%), Positives = 97/291 (32%), Gaps = 76/291 (26%)
Frame = +1
Query: 11257 CTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXETPECAQIECKKGWTRCS----SSYRCIP 11424
C FRC + CI E C +C+ G C + CIP
Sbjct: 17 CGVNSFRCLDGTCIPATLVCNYQKDCESAEDEFQSCTPPDCEAGQITCGQYIFNKTYCIP 76
Query: 11425 NWAFCNGQDDCRDNSDE------------------------------------------- 11475
C+ DC D +DE
Sbjct: 77 PHQRCDMTVDCVDGTDEAGCRNVNRMIFDVEVQHQNFVSQKRRNAMVIWIVEMVVMRRNV 136
Query: 11476 --------DKQRCPTCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRP 11631
D Q+C + +FRCA S CIPR ++CD DC D SDE SC TT
Sbjct: 137 RIIRNQLVDFQQCT----MDQFRCANS-LCIPRSYVCDGYKDCHDGSDE--KSC--TTTS 187
Query: 11632 CSESEFRC----NDGK--CIPGSKVCDGTIQCSDGLDESQ------CTLRRCLPGHRQC- 11772
C +++F C DGK CI S++CDG C D DE CT C R
Sbjct: 188 CPQNKFVCPRGTTDGKPLCIDRSQICDGKTDCEDKADEEATCSSVICTSLACRYKCRASP 247
Query: 11773 DDGTCIAEHKW--------CDRKKDCPNAADELHCEDVSRRTCSPFEFECA 11901
G C W C + +C ++ CE + + T + CA
Sbjct: 248 TGGVCYCPAGWILANDSTTCIDRDEC---SEWGFCEQLCKNTEGSYTCSCA 295
Score = 71.6 bits (174), Expect = 5e-10
Identities = 82/331 (24%), Positives = 107/331 (31%), Gaps = 71/331 (21%)
Frame = +1
Query: 8545 SAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDES 8724
S K C ++ G G C +F C +G CI T VC+ DC +++
Sbjct: 3 SLKGCTYMAADGSG-----------CGVNSFRCLDGTCIPATLVCNYQKDCES---AEDE 48
Query: 8725 LATCPGLPIDCRGVKVRCP----NTNICIQPADLCDGYDDCGDKADE------------- 8853
+C P DC ++ C N CI P CD DC D DE
Sbjct: 49 FQSCT--PPDCEAGQITCGQYIFNKTYCIPPHQRCDMTVDCVDGTDEAGCRNVNRMIFDV 106
Query: 8854 ----------------------------------NQLFCMNQQCAQHYVRCPSGRCIPET 8931
NQL QQC RC + CIP +
Sbjct: 107 EVQHQNFVSQKRRNAMVIWIVEMVVMRRNVRIIRNQLVDF-QQCTMDQFRCANSLCIPRS 165
Query: 8932 WQCDGDNDCSDGWDE---THTNCTD---------TAGKKICVGDYLFQCD-NLKCISRAF 9072
+ CDG DC DG DE T T+C T GK +C+ D CD C +A
Sbjct: 166 YVCDGYKDCHDGSDEKSCTTTSCPQNKFVCPRGTTDGKPLCI-DRSQICDGKTDCEDKA- 223
Query: 9073 IXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYEC-IPRAWLCDGDVTCA 9249
C + CT C + + C P W+ D T
Sbjct: 224 --------------DEEATCSSVICT--SLACRYKCRASPTGGVCYCPAGWILANDSTTC 267
Query: 9250 GGEDESTE------LCKTEKKECNKGEFRCS 9324
DE +E LCK +G + CS
Sbjct: 268 IDRDECSEWGFCEQLCKN-----TEGSYTCS 293
Score = 69.7 bits (169), Expect = 2e-09
Identities = 71/275 (25%), Positives = 116/275 (41%), Gaps = 16/275 (5%)
Frame = +1
Query: 7654 KVMAIDTAGEHLSTIASGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGS 7833
+ + D E++ I +LA+D SG L+W++ + +SG R+ S G
Sbjct: 3848 QALDFDPRSEYVFWIDGESGLTSLAMDWISGNLYWTE--FDSSGTTLFGRVMVSKADGRY 3905
Query: 7834 RKVIVSESISLPAAIAVD-------FRNQKIYWADVNRLNIEVADYDGQNRKVIASGYRA 7992
R+ +++ + +P +I VD + + +YWAD IE + DG NRK+I G
Sbjct: 3906 RRSLITVGLEIPTSIVVDPELGKAIWADHVLYWADSKLNTIESIEQDGSNRKIILKGDSL 3965
Query: 7993 K---SLDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVSDRRIPGALRVFASES-DVRTR 8160
K SLD+++ LY + + R DK E +V G ++V+ + ++ R
Sbjct: 3966 KHPISLDVFENSLYWITKRTGELIRQDKFGRGVPEIIVKHVPNSGGVKVYHQQRYNISLR 4025
Query: 8161 NQVCNALTSQLCKTDNGGCDQLCTVVADDIGLAASKVQCSCNDTY-ELVQEPGKDYPTQC 8337
N + LC GG LC +D IG + N+ + + E P C
Sbjct: 4026 NLCHEDQCTHLCVPIPGGNRCLC---SDSIGPLQQRETIRSNERHCDATNERPLPAPRIC 4082
Query: 8338 VLRG----SNSEPAKECLPPYNFQCGDGSCILLGA 8430
R E +C P F G+ I+LGA
Sbjct: 4083 PCRNGGLCQEVEDKLQCDCPAPFH-GEFCEIMLGA 4116
Score = 64.7 bits (156), Expect = 6e-08
Identities = 80/352 (22%), Positives = 120/352 (33%), Gaps = 30/352 (8%)
Frame = +1
Query: 10774 GCSHLCLIGAGG--NGYTC---SCPDQFVLLSDQKTCE-----------PNCTERQFACG 10905
GC+++ G+G N + C +C ++ + QK CE P+C Q CG
Sbjct: 6 GCTYMAADGSGCGVNSFRCLDGTCIPATLVCNYQKDCESAEDEFQSCTPPDCEAGQITCG 65
Query: 10906 G---DDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRPFQIXXX 11076
+ CIP CD DC DG+DE G C N N ++
Sbjct: 66 QYIFNKTYCIPPHQRCDMTVDCVDGTDEAG---------------CRNVN-----RMIFD 105
Query: 11077 XXXXXXXXXEQNCDKACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEADTLCMSAERN 11256
Q A W+ + R + R+ D +
Sbjct: 106 VEVQHQNFVSQKRRNAMVIWIVEMVVMRRNV-----------RIIRNQLVDF------QQ 148
Query: 11257 CTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXETPECAQIECKKGWTRCSSSYRCIPNWAF 11436
CT ++FRC N+ CI +++
Sbjct: 149 CTMDQFRCANSLCIPRSY-----------------------------------------V 167
Query: 11437 CNGQDDCRDNSDEDKQRCPTCDDVGEFRC---ATSGK--CIPRRWMCDTENDCGDNSDEL 11601
C+G DC D SDE +C +F C T GK CI R +CD + DC D +DE
Sbjct: 168 CDGYKDCHDGSDEKSCTTTSCPQ-NKFVCPRGTTDGKPLCIDRSQICDGKTDCEDKADE- 225
Query: 11602 DASCGGTTRPCSESEFRCNDGKCIPGSKVC---DGTIQCSDG---LDESQCT 11739
+A+C ++C + P VC G I +D +D +C+
Sbjct: 226 EATCSSVICTSLACRYKC---RASPTGGVCYCPAGWILANDSTTCIDRDECS 274
Score = 59.7 bits (143), Expect = 2e-06
Identities = 86/401 (21%), Positives = 155/401 (38%), Gaps = 34/401 (8%)
Frame = +1
Query: 5260 NPCSHLCLLNNKNTFTCKCPMGEKLDASGKKC--IDDAKPFLVIIQ------------KT 5397
N C+H C+ + ++ C+C G +L A GK C ID+ + K
Sbjct: 2872 NQCAHKCI-DTPTSYYCECNPGYRLLADGKACEDIDECVETPQVCSQQCQNTPGSFYCKC 2930
Query: 5398 NVFGIEMNSASEKETPVLAGMVPLSGLGNAF---DAAYDALSEEMFILEHTNHAKTLAQI 5568
N + E +A E ++P N + + + DAL+ + + N A
Sbjct: 2931 NHYWYE-RAADEHTCKRRDNIIPWIIFTNKYYVRNMSIDALNYSLMHQDLINVVALDADY 2989
Query: 5569 ---------TTDSAIYRSTVNGGNKTKMFSSAVPDDAYCL---GFDWNGRNLVVGNKITQ 5712
T I+R+ + GG K + + D+ L DW GR L ++ +
Sbjct: 2990 GDQMLYFCDVTAKTIFRAPIAGGEK----EAIIRHDSLGLEGIAVDWIGRKLYWLDRHAK 3045
Query: 5713 TIEIIRTQGKQYRSVILSNDQSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGL 5892
+++ G ++++ GY+++ A + + G+
Sbjct: 3046 HLDVAELNGTNRKTLLTG-------IADPRAIVVHPGTGYLYFTS---WHLQAYIGKMGM 3095
Query: 5893 DGSN--PLVIASNDLAELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQ 6066
DGSN ++ +D+A + + ID R+++++A I+ +G +R VLS G
Sbjct: 3096 DGSNFTRILTWEDDIAWPNALTIDYFTDRIFWADAHLDYIAFADLEGHNRRKVLS-GTAV 3154
Query: 6067 PN--GLAFYGDRLFYADSAFDSIEVATINGDSQPPQWTHFKKDVENLANIKALQP-RASS 6237
P+ + + D +F+ D +I A + +I A P R
Sbjct: 3155 PHVFAITIFDDFIFWTDWNLKAISRAE---KFSGYNLRVLRNTTHRPYDIHAYHPLRQLP 3211
Query: 6238 SGHPCHINNGNCDHICIPLMFAQRTCTCANGYVKDGQTSCK 6360
+PC+ NNG C H+C L+ + GY + G TS K
Sbjct: 3212 YNNPCNENNGGCSHLC--LISPPASSYLLEGYGQPGVTSYK 3250
Score = 57.8 bits (138), Expect = 8e-06
Identities = 48/200 (24%), Positives = 86/200 (43%), Gaps = 14/200 (7%)
Frame = +1
Query: 6751 SSIAVDPVSRYLYWADQGQKPT-----IQRSFLDGSRREVIVSSGIAEPTDLVVDV---- 6903
+S+A+D +S LYW + T + S DG R +++ G+ PT +VVD
Sbjct: 3869 TSLAMDWISGNLYWTEFDSSGTTLFGRVMVSKADGRYRRSLITVGLEIPTSIVVDPELGK 3928
Query: 6904 ---ASKMIYWSDAKMDGIYRVRSTGGTPELVRSDIASAAGVALH--GQNMYWTDNRLEKL 7068
A ++YW+D+K++ I + G +++ + ++L ++YW R +L
Sbjct: 3929 AIWADHVLYWADSKLNTIESIEQDGSNRKIILKGDSLKHPISLDVFENSLYWITKRTGEL 3988
Query: 7069 FRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRASSPCQITDNLRKSPCTQLCF 7248
R P + + + G V V+ +Q R + + + + CT LC
Sbjct: 3989 IRQDKFGRGV-----PEIIVKHVPNSGGVKVY---HQQRYN--ISLRNLCHEDQCTHLCV 4038
Query: 7249 ATPGTQTPTCSCARGVLKGR 7308
PG CS + G L+ R
Sbjct: 4039 PIPGGNRCLCSDSIGPLQQR 4058
Score = 51.6 bits (122), Expect = 6e-04
Identities = 79/356 (22%), Positives = 141/356 (39%), Gaps = 27/356 (7%)
Frame = +1
Query: 12679 ELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAVSE 12858
+ +Y+ D + IYR QS G+++ + GV +AVD+ NL+
Sbjct: 671 QYIYYSDVLQDVIYRV-----RQSGAGREVVLASQNEGV--EGLAVDWVAKNLYY----- 718
Query: 12859 NIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRIC 13038
+ +RK ++ + +N + ++ + +L++P A++ P+ G I
Sbjct: 719 ------IDSRKGTLNV-LSTRNVTY-----------RRTLLKNLKRPRAIVIHPNQGYIF 760
Query: 13039 YSDAGLHAKIECADMDGTHRQIIVKDLVFS-PTSMAIDEGKGNRIYWVDPKYRRVDAVNI 13215
+S+ A I A DG++ I+ K+L P +AID K +R+YW D V N+
Sbjct: 761 FSEWDRPANISRAYTDGSN-LIVFKNLSLGWPNGLAIDFAK-DRLYWCDALLDHVQHSNL 818
Query: 13216 DGSERTTVVHD--RHIPYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHT 13389
+G++ +V RH P+++ ++E +Y + K + S+L E
Sbjct: 819 NGTDVRSVKSKLIRH-PFSMAIYEQWMYITDWRLDAIIRLHKETGEQESILVRQPETNRL 877
Query: 13390 VRVSQKYAKDTQRTVSG--C--ERAQCSHLCVSLPSTGF----------ACLCPDGIVPQ 13527
V + Y++ Q + C + C LC ++P C CP G Q
Sbjct: 878 YGV-KVYSRSIQTFLHDHPCFNDNGGCEKLCFAIPQNNTNKYGITRLTKVCGCPYGERIQ 936
Query: 13528 LDGSCATQHVEALTMPKQCKCTNGGKCR----------LDGSCECTSDFEGDQCEK 13665
+G EA + C T C DG +C + + C K
Sbjct: 937 ENGRTCAPDPEAEPPLEACPNTWDFTCANQRCISHAWVCDGENDCLDNSDERNCTK 992
Score = 51.2 bits (121), Expect = 7e-04
Identities = 89/417 (21%), Positives = 142/417 (33%), Gaps = 10/417 (2%)
Frame = +1
Query: 2083 YKCACPIGQKLVNGK----RCIDSIDYLLFSSNKIVRGIFPEINEKALAEAVLPISPISQ 2250
Y C+C G +L + + R +D+ +LF++ +R P +
Sbjct: 3792 YSCSCRQGFELSDNRSGVCRAVDTNMMILFANGPGIRAYDPYDKQ--------------- 3836
Query: 2251 RRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWISKQ 2430
E+E + D + Y DGE GL S++ DWIS
Sbjct: 3837 -------EIEVIANEKRVQALDFDPRSEYVFWIDGES----------GLTSLAMDWISGN 3879
Query: 2431 LYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITE-LRDPVSVVVHPWKGLLFYAEAMRP 2607
LY+ + +S G + D RR LIT L P S+VV P G +A+
Sbjct: 3880 LYWTEF--DSSGTTLFGRVMVSKADGRYRRSLITVGLEIPTSIVVDPELGKAIWAD---- 3933
Query: 2608 AAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKN---VV 2778
H+ L W D+ L TI ++ DG N ++
Sbjct: 3934 ------HV---------------------------LYWADSKLNTIESIEQDGSNRKIIL 3960
Query: 2779 KLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACS 2958
K D P+++ + +Y++ +R + R K G +I+ + + + K
Sbjct: 3961 KGD-SLKHPISLDVFENSLYWITKRTGELIRQDKFGRGVPEIIVKHVPNSGGV---KVYH 4016
Query: 2959 HQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINKENNHSCQKDP 3138
Q I S + C QCT LC P + +C C P
Sbjct: 4017 QQRYNI---SLRNLCHEDQCTHLCVPIPGGN-------RCLCSDSI------------GP 4054
Query: 3139 AEKIEQLCSSNSTQFQCKNGRCIPKEWKCDGEND--CLDESDEIDEKGDKCFHETEC 3303
++ E + SN N R +P C N C + D++ FH C
Sbjct: 4055 LQQRETI-RSNERHCDATNERPLPAPRICPCRNGGLCQEVEDKLQCDCPAPFHGEFC 4110
Score = 48.1 bits (113), Expect = 0.006
Identities = 23/52 (44%), Positives = 28/52 (53%)
Frame = +1
Query: 10879 CTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQC 11034
CT QF C ++ CIP+ + CDG DC DGSDE C CP +F C
Sbjct: 149 CTMDQFRCA--NSLCIPRSYVCDGYKDCHDGSDEKS---CTTTSCPQNKFVC 195
Score = 43.5 bits (101), Expect = 0.15
Identities = 30/100 (30%), Positives = 39/100 (39%), Gaps = 12/100 (12%)
Frame = +1
Query: 9541 AQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAE--------- 9693
A S C F+C G CI VC+ DC DE C +C +
Sbjct: 11 AADGSGCGVNSFRCLDGTCIPATLVCNYQKDCESAEDEFQSCTPPDCEAGQITCGQYIFN 70
Query: 9694 KPLC---EQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVN 9804
K C Q+C DM + DC +G +D+ C NVN
Sbjct: 71 KTYCIPPHQRC-DMTV----DCVDG-----TDEAGCRNVN 100
>gi|50750792|ref|XP_422146.1| PREDICTED: similar to Low-density
lipoprotein receptor-related protein 1B precursor
(Low-density lipoprotein receptor-related protein-deleted
in tumor) (LRP-DIT) [Gallus gallus]
Length = 3738
Score = 1525 bits (3949), Expect = 0.0
Identities = 1081/3597 (30%), Positives = 1643/3597 (45%), Gaps = 94/3597 (2%)
Frame = +1
Query: 3154 QLCSSNSTQFQCKNGRCIPKEWKCDGENDCLDESDEIDEKGDKCFHETECAENTIKCRNT 3333
QLC + QFQC N RCI W+CDG++DCLD SDE D CF+ + C EN KC+N
Sbjct: 4 QLCKAE--QFQCNNKRCIHDRWRCDGDDDCLDGSDE---HADICFNHS-CPENQFKCQNN 57
Query: 3334 KKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNHRCIPEQWKXXXXXXX 3513
+ CIP + K C C +F C N RCIP W
Sbjct: 58 R-CIPKRWLCDGANDCGNNEDESNKTCA---ARTCQFDQFSCGNGRCIPTSWLCDREDDC 113
Query: 3514 XXXXXEKLEMCGNATCAA-NQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSA 3690
E + C TC QF C NGRCI WLCD D+DC DG+DE C CSA
Sbjct: 114 GDQTDE-MTSCEFPTCEPLTQFICKNGRCISSKWLCDSDDDCGDGSDE--LGCIH-SCSA 169
Query: 3691 LQFRCANGRQCVPLRNHXXXXXXXXXXXXXXXXAVTAES------CTPDQFKCVSSGLCI 3852
QFRC NGR C+P T E C +F+C G C+
Sbjct: 170 DQFRCYNGR-CIPSHWACDGDNDCGDYSDETRTNCTKEETPAPGRCNGKEFQCSPDGNCV 228
Query: 3853 PASWKXXXXXXXXXXSDEPKFGCTSG-RQCSSD-QFKC-GNGRCILNNWLCDGENDCGDG 4023
P W+ SDE GC R C +F C GRCI WLCDG+ DC D
Sbjct: 229 PELWRCDGEKDCEDGSDEK--GCNGTLRLCDEKTKFSCVSTGRCISKAWLCDGDIDCEDQ 286
Query: 4024 SDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGGRCARDLC 4203
SDE + C+ M C C ND C+ +LC+G+ CP G+DEG C D C
Sbjct: 287 SDEDN---CEGYM----CGPPKYPCANDTSICLQPEKLCNGRRDCPDGSDEGDLC--DEC 337
Query: 4204 SADRAGCSFKCHNSPNGPI-CSCPFGEQL-VNKTKCEPENECLDSSSCSQRCKDEKHGFT 4377
S + GCS +C P G I CSCP G L V+ CE + C CSQ C+ K+
Sbjct: 338 SLNNGGCSHQCSVVPGGRIVCSCPSGFNLSVDNKTCEIMDYCTKHLKCSQVCEQHKNNVK 397
Query: 4378 CSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGAIVENAIALAW 4557
CSC EG++L D C ++ + + I S R+ I D ++ + N IAL +
Sbjct: 398 CSCYEGWKLSKDGENC-ISTDPFEAFIIFSIRHEIRKIDLHKRDYSLLVPGLRNTIALDF 456
Query: 4558 DSLTDRIYWSDIREKKILSANRNGTNAT----VFIADGLDITEGIALDWVGRNLYWVDSS 4725
+YW+D+ E KI + T V + GL EG+ +DW+ N+YW+DS+
Sbjct: 457 HFSQSLLYWTDVVEDKIYRGKLSDTGGVSAIEVIVQHGLATPEGLTVDWIAGNIYWIDSN 516
Query: 4726 LNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQN-PCIERASMDGTDR 4902
L+ IEVA L D RT L+ + PR IA+DPR G++FWTDW N P IE ASM G +R
Sbjct: 517 LDQIEVAKL-DGTLRTTLIAGAMEHPRAIALDPRYGILFWTDWDANFPRIESASMSGAER 575
Query: 4903 QIIVKTKIY--WPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHA 5076
+II K WPN + +D+ R+ + D++ D I YDG+G +++ +++ HP A
Sbjct: 576 KIIYKDMDTGAWPNGLTVDHFEKRIVWTDARSDAIYSALYDGTGMIEIIRGHEYLSHPFA 635
Query: 5077 LAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCS 5256
++++ +Y++D R L K+ G T ++ + HP QP
Sbjct: 636 VSLYGSEVYWTDWRTNTLAKANKW-TGQNVSVIQKTSAQPFDLQIYHPSRQP-------- 686
Query: 5257 TNPCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNVFGIEMNSASEK 5436
+ K FL+ +++ + G+++++
Sbjct: 687 ----------------------------------QERKKFLLYARRSEIRGVDIDNPYFN 712
Query: 5437 ETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNGGNK 5616
+ A VP + + +DA+ E ++ + KT I R+ +NG
Sbjct: 713 F--ITAFTVP--DIDDVTVIDFDAVEERLYWTD----VKT-------QTIKRAFINGTGL 757
Query: 5617 TKMFSSAVPDDAYCLGFDWNGRNLV-VGNKITQT-IEIIRTQGKQYRSVILSNDQSXXXX 5790
+ S + L DW RNL + ++ +T I + G S+I D+
Sbjct: 758 ETIISRDI-QSIRGLAVDWISRNLYWISSEFDETQINVAHLDGSLKTSIIHGIDKPQCLA 816
Query: 5791 XXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAIDTTNT 5970
KG ++W D + A +DGSN ++ N + ++ID
Sbjct: 817 VHPV-------KGKLYWTDGN------TINMANMDGSNSKILFQNQKDPVG-LSIDYVEN 862
Query: 5971 RVYFSEAKAGRISSVTYDGQDRHYV--LSDGGRQPNGLAFYGDRLFYADSAFDSIEVATI 6144
++Y+ + G I+ DG + + + + + L +L++AD
Sbjct: 863 KLYWISSGNGTINRCNLDGGNLEIIDSMKEDLPKATALTIMDKKLWWAD----------- 911
Query: 6145 NGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHINNGNCDHICIPLMFAQRTCTCA 6324
+NLA I R + P + +T
Sbjct: 912 ----------------QNLAQIGTCNKRDGRN----------------PTILRNKT---- 935
Query: 6325 NGYVKDGQTSCKLFDESFVIVATKTKVIGYPIDETQSKGVAMEPIGGLSIT-GVDYDYES 6501
G K++D+ A + + G +D K A+ P+ G S G+D+ +
Sbjct: 936 -----SGVVHMKVYDK-----AAQQGIRGISLDPND-KMEALMPVSGTSFAVGIDFHAGN 984
Query: 6502 KTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINYNMYFINHDAERT 6681
TIY + G NK I+ ++ V+ + +G ++ +A+DWI N+Y+ +H
Sbjct: 985 DTIYWTDM-GFNK-ISRSKRDQTWKEDVVTNGLGR--VEGIAVDWIAGNIYWTDHGFNL- 1039
Query: 6682 NIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQRSFLDGSRREVIV 6861
IEV++L+G++R ++++ + P SIAV P YL+W + GQ P I +++LDGS + V+V
Sbjct: 1040 -IEVARLNGSFRYVIISQGLDQPRSIAVHPEKGYLFWTEWGQIPCIGKAYLDGSEKVVLV 1098
Query: 6862 SSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVR-STGGTPELVRSDI-ASAAGVALHGQN 7035
S GI P + +D +YW DA+ D I R+ +GG E+V S VA+ G
Sbjct: 1099 SLGIVWPNGISIDYEENKLYWCDARTDKIERIDLESGGNREIVLSGSNVDMFSVAVFGAY 1158
Query: 7036 MYWTDN-RLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRASSPCQITD 7212
+YW+D R K T + T + +LK+ V VF+ + + ++ C +
Sbjct: 1159 IYWSDRAHANGSIRRGHKNEATDAVTMRTGLGINLKE---VKVFNRARE-KGTNVCAKNN 1214
Query: 7213 NLRKSPCTQLCFATPGTQTPTCSCARGVLK--GRTCEEPDTYIMFSDGDKIIDVAIEPDV 7386
C QLC G TC+CA G L G TC + Y+++S + + + +
Sbjct: 1215 G----GCHQLCLYR-GKAQRTCACAHGYLAEDGITCLRHEGYLLYSGRTILKSIHLSDEN 1269
Query: 7387 KASRPLKDPF--PE-ISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAENPRLVFG- 7554
+ P++ P+ PE N+ D +L+ G N +FS + N +++
Sbjct: 1270 NLNSPVR-PYENPEYFKNVIALAFDYSLKGR--------GTNRIFFSDAHFGNIQVIKDN 1320
Query: 7555 -ASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVM--AIDTAG------EHLSTIASG 7707
A ++ + + + + +Y+T+ + +D E + T++
Sbjct: 1321 WAGRRVLIENVGSVEGLAYHRAWDTLYWTSSTTSSITRHTVDQRRRGAFNREAVITMSED 1380
Query: 7708 DWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVD 7887
D + LA+D C L+FW++ + P I RS L+G + +VI+S I P + +D
Sbjct: 1381 DHPHVLALDECQNLMFWTNWNEQL------PSIMRSTLSGKNAQVIISTDILTPNGLTID 1434
Query: 7888 FRNQKIYWADVNRLNIEVADYDGQNRKVIASGYRAK--SLDIWDRWLYMSDPLSNGVFRI 8061
R +K+Y++D + IE +YDG R VI SL ++D +++ SD + + R
Sbjct: 1435 HRAEKLYFSDGSLGKIERCEYDGSQRYVIVKSGPGTFLSLAVYDDYIFWSDGVRRAILRS 1494
Query: 8062 DKESGSGLENVVSDRRIPGA-LRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLCTVV 8238
K +G + + SD IP + + A +D N+ C NGGC LC +
Sbjct: 1495 SKYTGGDTKVLRSD--IPHQPMGIIAVANDT-------NSCELSPCAQMNGGCHDLCLLT 1545
Query: 8239 ADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSEPAKECLPPYNFQCGDGSCI 8418
D +V CSC L+ + +CV + S E F+CG+G CI
Sbjct: 1546 PD------GRVNCSCRGDRILIDD------NRCVTKNSTCNIYSE------FECGNGECI 1587
Query: 8419 LLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHIDDCGDGSDEL 8598
TCD C D SDE YC R C + + C+NRRCI K C+ +DCGD SDE+
Sbjct: 1588 DYQLTCDGTAHCKDKSDEKLFYCENRGCRKGFKPCSNRRCISRNKVCDGRNDCGDNSDEI 1647
Query: 8599 DCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHD----EQVSDESLATCPGLPIDCRGV 8766
DC + AC F C++G CI ++ C+ DC D + ++ + A L I G
Sbjct: 1648 DCKDS-ACTSTEFRCADGTCIGKSAQCNQIIDCADASDEKNCNNTNCAYFYKLGIKSTGF 1706
Query: 8767 KVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQ-CAQHYVRCPSGRCIPETWQCD 8943
+ C +T++CI P +CDG +DCGD DE + N+ C ++Y CPSGRCI TW CD
Sbjct: 1707 -ISCNSTSLCILPEWICDGSNDCGDYTDELKCPVQNKPTCEENYFGCPSGRCILNTWLCD 1765
Query: 8944 GDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXXXXXXHSR 9123
G DC DG DE H + + + + C D KCIS+ + S
Sbjct: 1766 GQKDCEDGVDELHCDSSCSWNQFACSAD--------KCISKQW-TCDGEDDCGNGLDESD 1816
Query: 9124 HGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECN 9303
CG+ TC F C + + C+P WLCDG+ C G DE + C+
Sbjct: 1817 AICGSVTCAVGTFSCLGS-------HACVPHHWLCDGERDCPNGSDELSTAGCAPNNTCD 1869
Query: 9304 KGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANC-----TYSSCQPDFFQCANHKCVPNS 9468
+ F C N CI + CD D+DC DGSDE C Y C P F CA+ +C+ NS
Sbjct: 1870 ENAFMCRNNICIPKQFVCDHDDDCGDGSDESLECGKYNKRYRRCHPGEFTCADGRCLLNS 1929
Query: 9469 -WKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDR 9645
W+CDG+ DC D SDE K S++++ C++ F C +G+CI VC+ DC+D
Sbjct: 1930 QWQCDGDFDCPDHSDEAPINKKCKSSEQS--CNSSFFMCKNGKCIPQNNVCNNKEDCSDG 1987
Query: 9646 SDESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNECYEGIS 9825
SDE S C I+EC + C Q C D+ +GYKC C+ GF + D K+C +++EC G
Sbjct: 1988 SDEKS-CHINECLSKKVSGCSQDCQDLPVGYKCKCWPGFQLK-DDGKTCTDIDECSSGFP 2045
Query: 9826 GCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYE 10005
CSQ+C + G+YKC C DGY++ D+ + ++ + EPF +LA+ H IRKIS DG+ Y
Sbjct: 2046 -CSQQCINTYGTYKCLCADGYEIQPDNLNGCKSLSDEEPFLILADHHEIRKISTDGSNYT 2104
Query: 10006 LAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGI 10185
L QG +NV+++D D E+ Y ID + R++ ++ S + V HN +
Sbjct: 2105 LLKQGLNNVIAIDFDYREEFIYWIDSSRPNGSRINRMRLNG--SDIKVV--HNTAVPNAL 2160
Query: 10186 AVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFFTEWSLQ 10365
AVDW+G+ LY + ++R I V +++G + L+ R++ P+ + + P GYL++ +
Sbjct: 2161 AVDWIGKNLYWSDTEKRIIEVSKVNGLYPTVLVSKRVKFPRDLSLDPQAGYLYWIDCCEY 2220
Query: 10366 PYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNG 10545
P+IGR+ +DGS + + E + P A+ IDY + RL+W D N I F D DG+
Sbjct: 2221 PHIGRVGMDGSSQTV-----VIETQISRPMALTIDYVNHRLYWADE--NHIEFSDMDGSH 2273
Query: 10546 RRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDLRIVH 10725
R +P Q V ++ +F+DY+YW D + + R K +G + L + D+++ H
Sbjct: 2274 RHKVPNQDIPGVIALTLFEDYIYWTDGKTKSLNRAHKTSGLDRLSLINSWHTITDIQVYH 2333
Query: 10726 PMRQP-AYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTCEPNCTERQFAC 10902
RQP + C NNGGCSHLCL+ A G +TC+CP F L +D KTC NCT QF C
Sbjct: 2334 SYRQPDVSKHLCTVNNGGCSHLCLL-APGKMHTCACPTNFYLAADNKTCLSNCTASQFRC 2392
Query: 10903 GGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRPFQIXXXXX 11082
D KCIP W CD DC DGSDEP E C + C G FQC C P I
Sbjct: 2393 KTD--KCIPFWWKCDTVDDCGDGSDEPEE--CPEFRCQPGRFQCGTGLCALPAFICDGEN 2448
Query: 11083 XXXXXXXEQNCD-KACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEADTLCMSAERNC 11259
E NCD C FKC +CIP DE D E +C
Sbjct: 2449 DCGDNSDELNCDTHVCLSGQFKCTKNQKCIPINLRCNGQDDCGDEEDERD----CPENSC 2504
Query: 11260 TAEEFRCNNNK-CIAKAWRXXXXXXXXXXXXETPECAQIECKKGWTRCSSSYRCIPNWAF 11436
+ + F+C K CI+K W E C + C +C ++ CIP+
Sbjct: 2505 SPDHFQCQTTKHCISKLWVCDEDPDCADGSDEA-NCDKKTCGPHEFQCKNN-NCIPDHWR 2562
Query: 11437 CNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCG 11616
C+ Q+DC DNSDE+ + TC + +F CA +G C+ R+ CD + DC D SDE G
Sbjct: 2563 CDSQNDCGDNSDEENCKPQTC-TLKDFLCA-NGDCVSARFWCDGDYDCADGSDERYCETG 2620
Query: 11617 GTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQC--TLRRCLPGHRQCDDGTCI 11790
CS +F+C++G+CI CDG C G DE C C C G CI
Sbjct: 2621 -----CSRDQFQCSNGQCISAKWRCDGHEDCKLGDDEKNCEPASPTCSVSEYICASGGCI 2675
Query: 11791 AEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFECAN-SVCIPRKFMXXXXXXXXXXSD 11967
+ C+ + DC + +DE+ C C +F C N + CIP +++ SD
Sbjct: 2676 SASLKCNGEYDCADGSDEMDCV----TECKEDQFRCKNKAYCIPVRWLCDGIHDCVDGSD 2731
Query: 11968 ETS---------------SECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSD 12102
E E C P +RC ++R+CL Q+CN +DCG N D
Sbjct: 2732 EEDCVQGCVLIGIVFCAIKETIKFPCPPTRPYRCRNNRVCLRPEQICNEVDDCGDNSDED 2791
Query: 12103 EHLSMCSSFS-EYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCE 12279
C + + C D+F C + KC+ + CD DDCGD SDE C + +CE
Sbjct: 2792 H----CDKITYKARPCKKDEFTCNDKKCIPMELQCDWFDDCGDGSDEQDCKISVTEYTCE 2847
Query: 12280 AFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGSY 12459
N G C + C C+ GF+ + + ++C DI+EC C+Q C N KGSY
Sbjct: 2848 DNVNPCGDDAYCNQTKTSLLCQCKPGFQRNEMN-RQCEDINECMVFGACSQHCNNVKGSY 2906
Query: 12460 LCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDS-LVQLSLHGSGTNRHXXXXXXX 12636
C C ++Y+ C+AKG V+ A+D+ ++ + + ++ H
Sbjct: 2907 RCACEKNYKE-------WNNSCKAKGSEEQVLYVANDTDILGFAYPFNYSDVHQQISHIE 2959
Query: 12637 XXXXXXXXXXXPRKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVV------ 12798
+ ++ W T + + H+ +K + G++
Sbjct: 2960 HNSRITGMDAYFQGNMIVW-----STHFNPGGIFYKKLHDKEKRQ---SNSGLICPEFKR 3011
Query: 12799 PTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIV 12978
P IAVD+ GN++ S T + I N G + +G +++
Sbjct: 3012 PRGIAVDWIAGNIYWTDHSRMHWFSYYTTHWTSLRYSI---NVGQL-----NGPNCTRLL 3063
Query: 12979 AGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGK 13158
+P A+ P G + ++ G + IE + MDGT R+I+V+ + PT + +D+
Sbjct: 3064 TSIAGEPYAIAVNPKKGMMYWTVIGDRSHIEESSMDGTLRRILVQKNLQRPTGLVVDQ-F 3122
Query: 13159 GNRIYWVDPKYRRVDAVNIDGSERTTVVHDRH---IPYAVDVFENHIYWLSRESKTLYVQ 13329
R++W D + + +V DGS+ V + P+ +D+FE++IY ++ V
Sbjct: 3123 SQRLFWADFELSVIGSVLFDGSDSVVSVSTKQGLLHPHRIDIFEDYIYGAGPKNGAFRVH 3182
Query: 13330 DKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTGFACLCP 13509
KFGR V L+ D++ + + +Y + + C C +C+ PS G +C CP
Sbjct: 3183 -KFGRSLVEYLSVDVDKAKSALIFHRYKQ--MDLPNPCLDLTCEFICLLNPS-GASCACP 3238
Query: 13510 DGIVPQLDGSCATQHVEALTMPKQCK--CTNGGKCRL----DGSCECTSDFEGDQCE 13662
+G ++G+C Q + + CK C NGGKC + D C C + G++CE
Sbjct: 3239 EG-KSLVNGTCVDQSL----LDDTCKLTCENGGKCIINEKGDPRCHCWPSYSGERCE 3290
Score = 447 bits (1151), Expect = e-123
Identities = 385/1491 (25%), Positives = 622/1491 (40%), Gaps = 110/1491 (7%)
Frame = +1
Query: 1222 LNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSL 1401
L+P + E + ++ F GIDF G+ I+WTD + + S D+ + L
Sbjct: 957 LDPNDKMEALMPVSGTSFAVGIDFHAGNDTIYWTD-MGFNKISRSKRDQTWKEDVVTNGL 1015
Query: 1402 KSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGE 1581
+ +AVDWI +Y + G I+V+ +G R V+++ GL P IA+ P +G
Sbjct: 1016 GRV---EGIAVDWIAGNIYWTDHGFNLIEVARLNGSFRYVIISQGLDQPRSIAVHPEKGY 1072
Query: 1582 MFFTNQLKLEA---AAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDY 1752
+F+T ++ A +DG+ + LV+ +GI +D ++YW D + D++E ID
Sbjct: 1073 LFWTEWGQIPCIGKAYLDGSEKVVLVSLGIVWPNGISIDYEENKLYWCDARTDKIERIDL 1132
Query: 1753 Q-GNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRL-GVIQVEKFGSDTKLLWSNTENN 1926
+ G +R IV G NV F +A+F Y+YW+D G I+ T + T
Sbjct: 1133 ESGGNREIVLSGSNV--DMFSVAVFGAYIYWSDRAHANGSIRRGHKNEATDAVTMRTGLG 1190
Query: 1927 VFPMGISAYHPMAQPGPGQSECLAMKIENPCT--NADCEGMCILSKDNGGFGVGYKCACP 2100
+ + ++ + G N C N C +C+ CAC
Sbjct: 1191 INLKEVKVFNRAREKGT-----------NVCAKNNGGCHQLCLYRGK-----AQRTCACA 1234
Query: 2101 IGQKLVNGKRCIDSIDYLLFSSNKIVRGIFPEINEKALAEAVLPIS--PISQRRIGMYFE 2274
G +G C+ YLL+S I++ I +E L V P + I + F+
Sbjct: 1235 HGYLAEDGITCLRHEGYLLYSGRTILKSIHLS-DENNLNSPVRPYENPEYFKNVIALAFD 1293
Query: 2275 VECDVHG-NSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDNI 2451
G N F++D I I+ + G VL+ + + +++ LY+ +
Sbjct: 1294 YSLKGRGTNRIFFSDAHFGNIQVIKDNWAGRR-VLIENVGSVEGLAYHRAWDTLYWTSST 1352
Query: 2452 RNSLEVVKIGETGLVHPDELVRRQLITELRD--PVSVVVHPWKGLLFYAEAMRPA-AIYR 2622
+S+ + + R +IT D P + + + L+F+ +I R
Sbjct: 1353 TSSITRHTVDQR---RRGAFNREAVITMSEDDHPHVLALDECQNLMFWTNWNEQLPSIMR 1409
Query: 2623 CHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVKLDIDNPI 2802
+ G+N QVI +T + P+ + ID +L + D L I ++DG + P
Sbjct: 1410 STLSGKNAQVIISTDILTPNGLTIDHRAEKLYFSDGSLGKIERCEYDGSQRYVIVKSGPG 1469
Query: 2803 P-VAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIP 2979
+++ + ++YI++ +I R K GG +K++R HQ I
Sbjct: 1470 TFLSLAVYDDYIFWSDGVRRAILRSSKYTGGDTKVLRS------------DIPHQPMGII 1517
Query: 2980 DDSRE-HPCRASQCTQ-------LCFATPSESHPNELEAKCACRQGFMINKEN-----NH 3120
+ + + C S C Q LC TP C+CR ++ +N N
Sbjct: 1518 AVANDTNSCELSPCAQMNGGCHDLCLLTPDG------RVNCSCRGDRILIDDNRCVTKNS 1571
Query: 3121 SCQ-------------------------KDPAEKIEQLCSSNSTQF---QCKNGRCIPKE 3216
+C KD +++ C + + C N RCI +
Sbjct: 1572 TCNIYSEFECGNGECIDYQLTCDGTAHCKDKSDEKLFYCENRGCRKGFKPCSNRRCISRN 1631
Query: 3217 WKCDGENDCLDESDEIDEKGDKCFH-ETECAENT-------------------------- 3315
CDG NDC D SDEID K C E CA+ T
Sbjct: 1632 KVCDGRNDCGDNSDEIDCKDSACTSTEFRCADGTCIGKSAQCNQIIDCADASDEKNCNNT 1691
Query: 3316 ---------------IKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKK 3450
I C +T CI + C KP C
Sbjct: 1692 NCAYFYKLGIKSTGFISCNSTSLCILPEWICDGSNDCGDYTDELK--CPVQNKPTCEENY 1749
Query: 3451 FQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNATCAANQFSCANGRCIPIYWLCDGDN 3630
F C + RCI W E + +++C+ NQF+C+ +CI W CDG++
Sbjct: 1750 FGCPSGRCILNTWLCDGQKDCEDGVDE---LHCDSSCSWNQFACSADKCISKQWTCDGED 1806
Query: 3631 DCYDGTDEDKERCPPVQCSALQFRCANGRQCVPLRNHXXXXXXXXXXXXXXXXAVTA--E 3804
DC +G DE C V C+ F C CVP A A
Sbjct: 1807 DCGNGLDESDAICGSVTCAVGTFSCLGSHACVPHHWLCDGERDCPNGSDELSTAGCAPNN 1866
Query: 3805 SCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEP----KFGCTSGRQCSSDQFKCGNGR 3972
+C + F C + +CIP + SDE K+ R+C +F C +GR
Sbjct: 1867 TCDENAFMC-RNNICIPKQFVCDHDDDCGDGSDESLECGKYN-KRYRRCHPGEFTCADGR 1924
Query: 3973 CILNN-WLCDGENDCGDGSDESS-ERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDG 4146
C+LN+ W CDG+ DC D SDE+ + CK+S + C C+N + CIP + +C+
Sbjct: 1925 CLLNSQWQCDGDFDCPDHSDEAPINKKCKSS--EQSCNSSFFMCKNGK--CIPQNNVCNN 1980
Query: 4147 KTHCPGGTDEGGRCARDLCSADRAGCSFKCHNSPNGPICSCPFGEQLVNKTK-CEPENEC 4323
K C G+DE + S +GCS C + P G C C G QL + K C +EC
Sbjct: 1981 KEDCSDGSDEKSCHINECLSKKVSGCSQDCQDLPVGYKCKCWPGFQLKDDGKTCTDIDEC 2040
Query: 4324 LDSSSCSQRCKDEKHGFTCSCDEGYELDVDKRT-CKVADNVKDTRIYVSNRNRIYYSDHK 4500
CSQ+C + + C C +GYE+ D CK + ++ + +++ + I
Sbjct: 2041 SSGFPCSQQCINTYGTYKCLCADGYEIQPDNLNGCKSLSD-EEPFLILADHHEIRKISTD 2099
Query: 4501 LDNWHTFGAIVENAIALAWDSLTDRIYWSDIREKKILSANRNGTNAT-VFIADGLDITEG 4677
N+ + N IA+ +D + IYW D NR N + + + +
Sbjct: 2100 GSNYTLLKQGLNNVIAIDFDYREEFIYWIDSSRPNGSRINRMRLNGSDIKVVHNTAVPNA 2159
Query: 4678 IALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWG 4857
+A+DW+G+NLYW D+ IEV+ + T+LV + V PR +++DP+ G ++W D
Sbjct: 2160 LAVDWIGKNLYWSDTEKRIIEVSKVNG-LYPTVLVSKRVKFPRDLSLDPQAGYLYWIDCC 2218
Query: 4858 QNPCIERASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQ 5037
+ P I R MDG+ + ++++T+I P + +DY R+Y+AD + I+F + DGS R +
Sbjct: 2219 EYPHIGRVGMDGSSQTVVIETQISRPMALTIDYVNHRLYWADE--NHIEFSDMDGSHRHK 2276
Query: 5038 VLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVH 5217
V ++ + AL +FED +Y++D + + L K +G +++ + H
Sbjct: 2277 V--PNQDIPGVIALTLFEDYIYWTDGKTKSLNRAHK-TSGLDRLSLINSWHTITDIQVYH 2333
Query: 5218 PVLQPVIKNNPCSTN--PCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDD 5364
QP + + C+ N CSHLCLL TC CP L A K C+ +
Sbjct: 2334 SYRQPDVSKHLCTVNNGGCSHLCLLAPGKMHTCACPTNFYLAADNKTCLSN 2384
Score = 356 bits (913), Expect = 1e-95
Identities = 335/1307 (25%), Positives = 512/1307 (38%), Gaps = 190/1307 (14%)
Frame = +1
Query: 2017 CTNAD-------CEGMCILSKDNGGFGVGYKCACPIGQKL----VNG-KRCIDSIDYLLF 2160
CT+ D C CI + +G YKC C G ++ +NG K D +L+
Sbjct: 2034 CTDIDECSSGFPCSQQCINT-----YGT-YKCLCADGYEIQPDNLNGCKSLSDEEPFLIL 2087
Query: 2161 SSNKIVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYR 2340
+ + +R I + + L + + + ++ D ++ D R
Sbjct: 2088 ADHHEIRKISTDGSNYTLLK----------QGLNNVIAIDFDYREEFIYWIDSSRPNGSR 2137
Query: 2341 IRPDGEGAAPVLVTHNDGL-FSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVR 2517
I + + V HN + +++ DWI K LY+ D + +EV K+ ++P LV
Sbjct: 2138 INRMRLNGSDIKVVHNTAVPNALAVDWIGKNLYWSDTEKRIIEVSKVNG---LYPTVLVS 2194
Query: 2518 RQLITELRDPVSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAID 2697
+++ + P + + P G L++ + I R +DG + V+ T + RP + ID
Sbjct: 2195 KRV----KFPRDLSLDPQAGYLYWIDCCEYPHIGRVGMDGSSQTVVIETQISRPMALTID 2250
Query: 2698 FAENRLCWGDTLLKTISCMDFDGKNVVKL-DIDNPIPVAITIMNEYIYYVHQRPYSIRRV 2874
+ +RL W D I D DG + K+ + D P +A+T+ +YIY+ + S+ R
Sbjct: 2251 YVNHRLYWADE--NHIEFSDMDGSHRHKVPNQDIPGVIALTLFEDYIYWTDGKTKSLNRA 2308
Query: 2875 HKKNG-GGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQ--CTQLCFATPS 3045
HK +G ++ + +I ++ QP D +H C + C+ LC P
Sbjct: 2309 HKTSGLDRLSLINSW----HTITDIQVYHSYRQP---DVSKHLCTVNNGGCSHLCLLAPG 2361
Query: 3046 ESHPNELEAKCACRQGFMINKENNHSCQKDPAEKIEQLCSSNST--QFQCKNGRCIPKEW 3219
+ H CAC F + +N + C SN T QF+CK +CIP W
Sbjct: 2362 KMHT------CACPTNFYLAADN-------------KTCLSNCTASQFRCKTDKCIPFWW 2402
Query: 3220 KCD----------------------------------------GENDCLDESDEID---- 3267
KCD GENDC D SDE++
Sbjct: 2403 KCDTVDDCGDGSDEPEECPEFRCQPGRFQCGTGLCALPAFICDGENDCGDNSDELNCDTH 2462
Query: 3268 ---------EKGDKCF----------------HETECAENT-----IKCRNTKKCIPAQX 3357
K KC E +C EN+ +C+ TK CI
Sbjct: 2463 VCLSGQFKCTKNQKCIPINLRCNGQDDCGDEEDERDCPENSCSPDHFQCQTTKHCISKLW 2522
Query: 3358 XXXXXXXXXXXXXXXVKYCKDGQ------KPVCAAKKFQCDNHRCIPEQWKXXXXXXXXX 3519
C DG K C +FQC N+ CIP+ W+
Sbjct: 2523 VCDEDPD-----------CADGSDEANCDKKTCGPHEFQCKNNNCIPDHWRCDSQNDCGD 2571
Query: 3520 XXXEKLEMCGNATCAANQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQF 3699
E E C TC F CANG C+ + CDGD DC DG+DE R CS QF
Sbjct: 2572 NSDE--ENCKPQTCTLKDFLCANGDCVSARFWCDGDYDCADGSDE---RYCETGCSRDQF 2626
Query: 3700 RCANG---------------------RQCVPLRNHXXXXXXXXXXXXXXXXAVTAES--- 3807
+C+NG + C P ++
Sbjct: 2627 QCSNGQCISAKWRCDGHEDCKLGDDEKNCEPASPTCSVSEYICASGGCISASLKCNGEYD 2686
Query: 3808 -------------CTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEP------------- 3909
C DQF+C + CIP W SDE
Sbjct: 2687 CADGSDEMDCVTECKEDQFRCKNKAYCIPVRWLCDGIHDCVDGSDEEDCVQGCVLIGIVF 2746
Query: 3910 -------KFGCTSGRQCSSDQFKCGNGR-CILNNWLCDGENDCGDGSDESSERGCKTSMN 4065
KF C R ++C N R C+ +C+ +DCGD SDE + K +
Sbjct: 2747 CAIKETIKFPCPPTRP-----YRCRNNRVCLRPEQICNEVDDCGDNSDE--DHCDKITYK 2799
Query: 4066 ARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGGRCARDLC------SADRAGCS 4227
AR C + C ND++ CIP+ CD C G+DE C + + + G
Sbjct: 2800 ARPCKKDEFTC-NDKK-CIPMELQCDWFDDCGDGSDEQD-CKISVTEYTCEDNVNPCGDD 2856
Query: 4228 FKCHNSPNGPICSCPFGEQLVNKTK-CEPENECLDSSSCSQRCKDEKHGFTCSCDEGYEL 4404
C+ + +C C G Q + CE NEC+ +CSQ C + K + C+C++ Y+
Sbjct: 2857 AYCNQTKTSLLCQCKPGFQRNEMNRQCEDINECMVFGACSQHCNNVKGSYRCACEKNYK- 2915
Query: 4405 DVDKRTCKVADNVKDTRIYVSNRNRIY---YSDHKLDNWHTFGAIVENAIALAWDSLT-- 4569
+CK A ++ +YV+N I Y + D I N+ D+
Sbjct: 2916 -EWNNSCK-AKGSEEQVLYVANDTDILGFAYPFNYSDVHQQISHIEHNSRITGMDAYFQG 2973
Query: 4570 DRIYWSD------IREKKILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVDSSLN 4731
+ I WS I KK+ + +N+ + I GIA+DW+ N+YW D S
Sbjct: 2974 NMIVWSTHFNPGGIFYKKLHDKEKRQSNSGL-ICPEFKRPRGIAVDWIAGNIYWTDHSRM 3032
Query: 4732 ---------------TIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQNP 4866
+I V L P LL +P IAV+P+KG+M+WT G
Sbjct: 3033 HWFSYYTTHWTSLRYSINVGQLNGPNCTRLLT-SIAGEPYAIAVNPKKGMMYWTVIGDRS 3091
Query: 4867 CIERASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLA 5046
IE +SMDGT R+I+V+ + P + +D + R+++AD +L I V +DGS ++
Sbjct: 3092 HIEESSMDGTLRRILVQKNLQRPTGLVVDQFSQRLFWADFELSVIGSVLFDGSDSVVSVS 3151
Query: 5047 SSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVL 5226
+ + + HPH + IFED +Y + + +V+ K+ EY S KA + H
Sbjct: 3152 TKQGLLHPHRIDIFEDYIYGAGPKNGAFRVH-KFGRSLV-EYLSVDVDKAKSALIFHRYK 3209
Query: 5227 QPVIKNNPCSTNPCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDA 5367
Q + NPC C +CLLN +C CP G+ L C+D +
Sbjct: 3210 QMDLP-NPCLDLTCEFICLLNPSGA-SCACPEGKSL--VNGTCVDQS 3252
Score = 304 bits (779), Expect = 4e-80
Identities = 246/906 (27%), Positives = 393/906 (43%), Gaps = 30/906 (3%)
Frame = +1
Query: 145 ASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXX-PHPGCKS-DQWQCDTYTWHS 318
A+ C + F C +G+CI T W P C+ Q+ C +
Sbjct: 84 AARTCQFDQFSCGNGRCIPTSWLCDREDDCGDQTDEMTSCEFPTCEPLTQFICK-----N 138
Query: 319 VSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCR 498
CI+ CD+ DC DGSDE C S CS+ F C +GR C CDG DC
Sbjct: 139 GRCISSKWLCDSDDDCGDGSDELGCIHS---CSADQ-FRCYNGR-CIPSHWACDGDNDCG 193
Query: 499 DLSDE-KDSCSRNHTA----CFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDT---- 651
D SDE + +C++ T C +F+C+ C+ + W CDG KDC DGSDE
Sbjct: 194 DYSDETRTNCTKEETPAPGRCNGKEFQCSPDGNCVPELWRCDGEKDCEDGSDEKGCNGTL 253
Query: 652 --CEFKKCTANEFQCKNK-RCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPG-TG 819
C+ K +F C + RC + + CD DC D SDED C Y C P K+ C T
Sbjct: 254 RLCDEK----TKFSCVSTGRCISKAWLCDGDIDCEDQSDEDNCEGYMCGPPKYPCANDTS 309
Query: 820 HCIDQLKLCDGSKDCADGADE----QQCSQNLCPSLGCQAGCHPSPHGG-ECTCPSGYKL 984
C+ KLC+G +DC DG+DE +CS N + GC C P G C+CPSG+ L
Sbjct: 310 ICLQPEKLCNGRRDCPDGSDEGDLCDECSLN---NGGCSHQCSVVPGGRIVCSCPSGFNL 366
Query: 985 DDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCV 1164
++TC ++ C + C Q+C H+ CSC + + L + G++ C+
Sbjct: 367 SVD-NKTCEIMDYCTKHLKCSQVCEQHKNNVKCSCY-EGWKLSKD---GEN-------CI 414
Query: 1165 SNNADKMKLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSA 1344
S + + + + R + +++ D + I +DF + ++WTD +
Sbjct: 415 STDPFEAFIIFSIRHEIRKIDLHKRDYSLLVPGLRNTI-ALDFHFSQSLLYWTDVVEDKI 473
Query: 1345 FSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVL 1524
+ + D G +S I+ + L P L VDWI +Y I+S +I+V+ DG RT L
Sbjct: 474 YRGKLSDTGGVSAIEVIVQHGLATPEGLTVDWIAGNIYWIDSNLDQIEVAKLDGTLRTTL 533
Query: 1525 LADGLTLPLDIALDPLRGEMFFT----NQLKLEAAAMDGTNRRTLVNTHTHQV--SGIVV 1686
+A + P IALDP G +F+T N ++E+A+M G R+ + +G+ V
Sbjct: 534 IAGAMEHPRAIALDPRYGILFWTDWDANFPRIESASMSGAERKIIYKDMDTGAWPNGLTV 593
Query: 1687 DITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGV 1866
D KR+ W D + D + S Y G + +G + HPF ++L+ +YWTDW +
Sbjct: 594 DHFEKRIVWTDARSDAIYSALYDGTGMIEIIRGHEYLSHPFAVSLYGSEVYWTDWRTNTL 653
Query: 1867 IQVEKF-GSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGM 2043
+ K+ G + ++ + + P + YHP QP + L + ++ G+
Sbjct: 654 AKANKWTGQNVSVI---QKTSAQPFDLQIYHPSRQPQERKKFLLYAR------RSEIRGV 704
Query: 2044 CILSKDNGGFGVGYKCACPIGQKLVNGKRCIDSIDYLLFSSNKIVRGIFPEINEKALAEA 2223
I DN F P ID + + F + + R + ++ + + A
Sbjct: 705 DI---DNPYFNFITAFTVP----------DIDDVTVIDFDAVE-ERLYWTDVKTQTIKRA 750
Query: 2224 VLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFS 2403
+ G+ + D+ D + +Y I + + + V H DG
Sbjct: 751 FI-------NGTGLETIISRDIQSIRGLAVDWISRNLYWISSEFD-ETQINVAHLDGSLK 802
Query: 2404 MS-FDWISK-QLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKG 2577
S I K Q V ++ L + + D + L +DPV + + +
Sbjct: 803 TSIIHGIDKPQCLAVHPVKGKLYWTDGNTINMANMDGSNSKILFQNQKDPVGLSIDYVEN 862
Query: 2578 LLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTI-SCM 2754
L++ + I RC++DG N ++I + P A+ + +L W D L I +C
Sbjct: 863 KLYWISSGN-GTINRCNLDGGNLEIIDSMKEDLPKATALTIMDKKLWWADQNLAQIGTCN 921
Query: 2755 DFDGKN 2772
DG+N
Sbjct: 922 KRDGRN 927
Score = 288 bits (736), Expect = 4e-75
Identities = 208/723 (28%), Positives = 310/723 (42%), Gaps = 56/723 (7%)
Frame = +1
Query: 139 NTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHS 318
N C DF C +G C+ + GC DQ+QC +
Sbjct: 2577 NCKPQTCTLKDFLCANGDCVSARFWCDGDYDCADGSDERYC-ETGCSRDQFQCS-----N 2630
Query: 319 VSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCR 498
CI+ RCD DC G DEK+C ++ CS ++CA G C S KC+G+YDC
Sbjct: 2631 GQCISAKWRCDGHEDCKLGDDEKNCEPASPTCSVSE-YICASGG-CISASLKCNGEYDCA 2688
Query: 499 DLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPD---------- 648
D SDE D T C + QFRC +K CI W+CDG DC DGSDE D
Sbjct: 2689 DGSDEMDCV----TECKEDQFRCKNKAYCIPVRWLCDGIHDCVDGSDEEDCVQGCVLIGI 2744
Query: 649 -------TCEFKKCTANEFQCKNKR-CQPRKFRCDYYDDCGDNSDEDECGEYR-----CP 789
T +F ++C+N R C + C+ DDCGDNSDED C + C
Sbjct: 2745 VFCAIKETIKFPCPPTRPYRCRNNRVCLRPEQICNEVDDCGDNSDEDHCDKITYKARPCK 2804
Query: 790 PGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCS---------QNLCPSLGCQAGCHPS 942
++ C CI CD DC DG+DEQ C N+ P G A C+ +
Sbjct: 2805 KDEFTC-NDKKCIPMELQCDWFDDCGDGSDEQDCKISVTEYTCEDNVNPC-GDDAYCNQT 2862
Query: 943 PHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEH 1122
C C G++ ++ +R C DINEC FG C Q C N + + C+C
Sbjct: 2863 KTSLLCQCKPGFQRNE-MNRQCEDINECMVFGACSQHCNNVKGSYRCAC----------- 2910
Query: 1123 GPGKDNLTMRGYCVSNNADKMKLFVARREGL----YRLNPKNPDEEVKKLASGEFIYGID 1290
K+ C + +++ L+VA + Y N + +++ + I G+D
Sbjct: 2911 --EKNYKEWNNSCKAKGSEEQVLYVANDTDILGFAYPFNYSDVHQQISHIEHNSRITGMD 2968
Query: 1291 FDYGDRKIFWTDRLAHSA-FSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIE 1467
+ I W+ F + D+ + L PR +AVDWI +Y +
Sbjct: 2969 AYFQGNMIVWSTHFNPGGIFYKKLHDKEKRQSNSGLICPEFKRPRGIAVDWIAGNIYWTD 3028
Query: 1468 SGSRR---------------IDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFT--- 1593
I+V +G T LL P IA++P +G M++T
Sbjct: 3029 HSRMHWFSYYTTHWTSLRYSINVGQLNGPNCTRLLTSIAGEPYAIAVNPKKGMMYWTVIG 3088
Query: 1594 NQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRI 1773
++ +E ++MDGT RR LV + + +G+VVD ++R++W D ++ + S+ + G+D +
Sbjct: 3089 DRSHIEESSMDGTLRRILVQKNLQRPTGLVVDQFSQRLFWADFELSVIGSVLFDGSDSVV 3148
Query: 1774 VAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFG-SDTKLLWSNTENNVFPMGISA 1950
+ HP + +F+ Y+Y + G +V KFG S + L + + +
Sbjct: 3149 SVSTKQGLLHPHRIDIFEDYIYGAG-PKNGAFRVHKFGRSLVEYLSVDVDKAKSALIFHR 3207
Query: 1951 YHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGKR 2130
Y M P NPC + CE +C+L+ G CACP G+ LVNG
Sbjct: 3208 YKQMDLP-------------NPCLDLTCEFICLLNPS------GASCACPEGKSLVNG-T 3247
Query: 2131 CID 2139
C+D
Sbjct: 3248 CVD 3250
Score = 274 bits (700), Expect = 5e-71
Identities = 212/783 (27%), Positives = 312/783 (39%), Gaps = 111/783 (14%)
Frame = +1
Query: 127 SASVNTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGC----KSDQWQ 294
S ++ S C +FRC DG CI + C K
Sbjct: 1644 SDEIDCKDSACTSTEFRCADGTCIGKSAQCNQIIDCADASDEKNCNNTNCAYFYKLGIKS 1703
Query: 295 CDTYTWHSVS-CIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSK 471
+ +S S CI CD DC D +DE CP +N F C GR C +
Sbjct: 1704 TGFISCNSTSLCILPEWICDGSNDCGDYTDELKCPVQNKPTCEENYFGCPSGR-CILNTW 1762
Query: 472 KCDGKYDCRDLSDE---KDSCSRNHTACFQYQ---------------------------- 558
CDG+ DC D DE SCS N AC +
Sbjct: 1763 LCDGQKDCEDGVDELHCDSSCSWNQFACSADKCISKQWTCDGEDDCGNGLDESDAICGSV 1822
Query: 559 ------FRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEF---KKCTANEFQCKNKRCQP 711
F C C+ W+CDG +DC +GSDE T C N F C+N C P
Sbjct: 1823 TCAVGTFSCLGSHACVPHHWLCDGERDCPNGSDELSTAGCAPNNTCDENAFMCRNNICIP 1882
Query: 712 RKFRCDYYDDCGDNSDED-ECGEY-----RCPPGK-------------WNCPG------- 813
++F CD+ DDCGD SDE ECG+Y RC PG+ W C G
Sbjct: 1883 KQFVCDHDDDCGDGSDESLECGKYNKRYRRCHPGEFTCADGRCLLNSQWQCDGDFDCPDH 1942
Query: 814 -------------------------TGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSL- 915
G CI Q +C+ +DC+DG+DE+ C N C S
Sbjct: 1943 SDEAPINKKCKSSEQSCNSSFFMCKNGKCIPQNNVCNNKEDCSDGSDEKSCHINECLSKK 2002
Query: 916 --GCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSC 1089
GC C P G +C C G++L D +TC+DI+EC+ C Q C N + C C
Sbjct: 2003 VSGCSQDCQDLPVGYKCKCWPGFQLKDD-GKTCTDIDECSSGFPCSQQCINTYGTYKCLC 2061
Query: 1090 LGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKLASG 1269
D + +Q ++ G C S + ++ L +A + +++ + + K
Sbjct: 2062 -ADGYEIQPDNLNG---------CKSLSDEEPFLILADHHEIRKISTDGSNYTLLKQGLN 2111
Query: 1270 EFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLK--------SLVYPRC 1425
I IDFDY + I+W D + S+I ++ L + P
Sbjct: 2112 NVI-AIDFDYREEFIYWIDSSRPNG-----------SRINRMRLNGSDIKVVHNTAVPNA 2159
Query: 1426 LAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTNQLK 1605
LAVDWI LY ++ R I+VS +G TVL++ + P D++LDP G +++ + +
Sbjct: 2160 LAVDWIGKNLYWSDTEKRIIEVSKVNGLYPTVLVSKRVKFPRDLSLDPQAGYLYWIDCCE 2219
Query: 1606 ---LEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIV 1776
+ MDG+++ ++ T + + +D R+YW D + +E D G+ R V
Sbjct: 2220 YPHIGRVGMDGSSQTVVIETQISRPMALTIDYVNHRLYWADE--NHIEFSDMDGSHRHKV 2277
Query: 1777 AQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYH 1956
+P L LF+ Y+YWTD + + K +L N+ + + I YH
Sbjct: 2278 PN--QDIPGVIALTLFEDYIYWTDGKTKSLNRAHKTSGLDRLSLINSWHTI--TDIQVYH 2333
Query: 1957 PMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKL-VNGKRC 2133
QP + C N C +C+L+ G + CACP L + K C
Sbjct: 2334 SYRQPDVSKHLCTV-------NNGGCSHLCLLAP-----GKMHTCACPTNFYLAADNKTC 2381
Query: 2134 IDS 2142
+ +
Sbjct: 2382 LSN 2384
Score = 176 bits (446), Expect = 1e-41
Identities = 98/257 (38%), Positives = 125/257 (48%), Gaps = 1/257 (0%)
Frame = +1
Query: 124 ISASVNTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXX-PHPGCKSDQWQCD 300
++A T S C + FRC KCI W P C+ ++QC
Sbjct: 2374 LAADNKTCLSNCTASQFRCKTDKCIPFWWKCDTVDDCGDGSDEPEECPEFRCQPGRFQCG 2433
Query: 301 TYTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCD 480
T C CD DC D SDE +C T C S F C ++C ++ +C+
Sbjct: 2434 TGL-----CALPAFICDGENDCGDNSDELNC--DTHVCLSGQ-FKCTKNQKCIPINLRCN 2485
Query: 481 GKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEF 660
G+ DC D DE+D C N +C F+C CI K WVCD DCADGSDE + C+
Sbjct: 2486 GQDDCGDEEDERD-CPEN--SCSPDHFQCQTTKHCISKLWVCDEDPDCADGSDEAN-CDK 2541
Query: 661 KKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLK 840
K C +EFQCKN C P +RCD +DCGDNSDE+ C C + C G C+
Sbjct: 2542 KTCGPHEFQCKNNNCIPDHWRCDSQNDCGDNSDEENCKPQTCTLKDFLC-ANGDCVSARF 2600
Query: 841 LCDGSKDCADGADEQQC 891
CDG DCADG+DE+ C
Sbjct: 2601 WCDGDYDCADGSDERYC 2617
Score = 146 bits (369), Expect = 1e-32
Identities = 91/263 (34%), Positives = 122/263 (45%), Gaps = 13/263 (4%)
Frame = +1
Query: 154 VCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXP--HPGCKSDQWQCDTYTWHSVSC 327
+C F+CN+ +CI W + C +Q++C + C
Sbjct: 5 LCKAEQFQCNNKRCIHDRWRCDGDDDCLDGSDEHADICFNHSCPENQFKC-----QNNRC 59
Query: 328 IAEYQRCDNITDCADGSDE--KDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRD 501
I + CD DC + DE K C A T F C +GR C S CD + DC D
Sbjct: 60 IPKRWLCDGANDCGNNEDESNKTCAARTCQFDQ---FSCGNGR-CIPTSWLCDREDDCGD 115
Query: 502 LSDEKDSCSRNHTACFQY-QFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTAN 678
+DE SC C QF C + +CI W+CD DC DGSDE C+A+
Sbjct: 116 QTDEMTSC--EFPTCEPLTQFICKN-GRCISSKWLCDSDDDCGDGSDELGC--IHSCSAD 170
Query: 679 EFQCKNKRCQPRKFRCDYYDDCGDNSDE--DECGEYRCP-PGKWN-----CPGTGHCIDQ 834
+F+C N RC P + CD +DCGD SDE C + P PG+ N C G+C+ +
Sbjct: 171 QFRCYNGRCIPSHWACDGDNDCGDYSDETRTNCTKEETPAPGRCNGKEFQCSPDGNCVPE 230
Query: 835 LKLCDGSKDCADGADEQQCSQNL 903
L CDG KDC DG+DE+ C+ L
Sbjct: 231 LWRCDGEKDCEDGSDEKGCNGTL 253
Score = 144 bits (364), Expect = 5e-32
Identities = 97/282 (34%), Positives = 132/282 (46%), Gaps = 4/282 (1%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQ 453
CK++Q+QC+ + CI + RCD DC DGSDE C +N F C + R
Sbjct: 6 CKAEQFQCN-----NKRCIHDRWRCDGDDDCLDGSDEHADICFNHSC-PENQFKCQNNR- 58
Query: 454 CFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADG 633
C CDG DC + DE + T F QF C + +CI SW+CD DC D
Sbjct: 59 CIPKRWLCDGANDCGNNEDESNKTCAARTCQFD-QFSCGN-GRCIPTSWLCDREDDCGDQ 116
Query: 634 SDEPDTCEFKKC-TANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCP 810
+DE +CEF C +F CKN RC K+ CD DDCGD SDE C + C ++ C
Sbjct: 117 TDEMTSCEFPTCEPLTQFICKNGRCISSKWLCDSDDDCGDGSDELGC-IHSCSADQFRC- 174
Query: 811 GTGHCIDQLKLCDGSKDCADGADEQQ--CSQNLCPSLG-CQAGCHPSPHGGECTCPSGYK 981
G CI CDG DC D +DE + C++ P+ G C G C P ++
Sbjct: 175 YNGRCIPSHWACDGDNDCGDYSDETRTNCTKEETPAPGRCNGKEFQCSPDGNCV-PELWR 233
Query: 982 LDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFT 1107
D + C D ++ +LC + + F+C G C +
Sbjct: 234 CDG--EKDCEDGSDEKGCNGTLRLC-DEKTKFSCVSTGRCIS 272
Score = 135 bits (339), Expect = 4e-29
Identities = 91/283 (32%), Positives = 126/283 (44%), Gaps = 5/283 (1%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDE-KDCPASTVDCSSQNVFMCADGR 450
C + Q++C T CI + +CD + DC DGSDE ++CP F C G
Sbjct: 2385 CTASQFRCKTD-----KCIPFWWKCDTVDDCGDGSDEPEECPEFRCQPGR---FQCGTGL 2436
Query: 451 QCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCAD 630
C + CDG+ DC D SDE + C + C QF+C +CI + C+G DC D
Sbjct: 2437 -CALPAFICDGENDCGDNSDELN-CDTH--VCLSGQFKCTKNQKCIPINLRCNGQDDCGD 2492
Query: 631 GSDEPDTCEFKKCTANEFQCKN-KRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNC 807
DE D C C+ + FQC+ K C + + CD DC D SDE C + C P ++ C
Sbjct: 2493 EEDERD-CPENSCSPDHFQCQTTKHCISKLWVCDEDPDCADGSDEANCDKKTCGPHEFQC 2551
Query: 808 PGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLD 987
+CI CD DC D +DE+ C C + C +G +
Sbjct: 2552 KNN-NCIPDHWRCDSQNDCGDNSDEENCKPQTCTL-------------KDFLCANGDCVS 2597
Query: 988 DRFHRTCSDINECAEFG---YCDQLCANHRPGFTCSCLGDCFT 1107
RF C +CA+ YC+ C+ R F CS G C +
Sbjct: 2598 ARF--WCDGDYDCADGSDERYCETGCS--RDQFQCS-NGQCIS 2635
Score = 133 bits (335), Expect = 1e-28
Identities = 77/220 (35%), Positives = 107/220 (48%), Gaps = 1/220 (0%)
Frame = +1
Query: 376 SDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQY 555
+D K C ++ C++ F C + C KCD DC D SDE + C C
Sbjct: 2376 ADNKTCLSN---CTASQ-FRCKTDK-CIPFWWKCDTVDDCGDGSDEPEECPEFR--CQPG 2428
Query: 556 QFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQC-KNKRCQPRKFRCDY 732
+F+C C +++CDG DC D SDE + C+ C + +F+C KN++C P RC+
Sbjct: 2429 RFQCGTGL-CALPAFICDGENDCGDNSDELN-CDTHVCLSGQFKCTKNQKCIPINLRCNG 2486
Query: 733 YDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPS 912
DDCGD DE +C E C P + C T HCI +L +CD DCADG+DE C + C
Sbjct: 2487 QDDCGDEEDERDCPENSCSPDHFQCQTTKHCISKLWVCDEDPDCADGSDEANCDKKTC-- 2544
Query: 913 LGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAE 1032
PH E C + + D H C N+C +
Sbjct: 2545 ---------GPH--EFQCKNNNCIPD--HWRCDSQNDCGD 2571
Score = 130 bits (327), Expect = 9e-28
Identities = 141/614 (22%), Positives = 250/614 (39%), Gaps = 9/614 (1%)
Frame = +1
Query: 1285 IDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYII 1464
IDFD + +++WTD + A ++ G + I ++S+ R LAVDWI+ LY I
Sbjct: 728 IDFDAVEERLYWTDVKTQTIKRAFINGTG-LETIISRDIQSI---RGLAVDWISRNLYWI 783
Query: 1465 ES--GSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTNQLKLEAAAMDGTNR 1638
S +I+V+ DG +T ++ G+ P +A+ P++G++++T+ + A MDG+N
Sbjct: 784 SSEFDETQINVAHLDGSLKTSII-HGIDKPQCLAVHPVKGKLYWTDGNTINMANMDGSNS 842
Query: 1639 RTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLA 1818
+ L V G+ +D ++YW+ + + G + I+ +P L
Sbjct: 843 KILFQNQKDPV-GLSIDYVENKLYWISSGNGTINRCNLDGGNLEIIDSMKEDLPKATALT 901
Query: 1819 LFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLA 1998
+ D KL W++ +AQ G
Sbjct: 902 IM----------------------DKKLWWADQN-------------LAQIGT------- 919
Query: 1999 MKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGKRCIDSIDYLLFSSNKIV 2178
C D IL G + K+ + ++ + +
Sbjct: 920 ------CNKRDGRNPTILRNKTSGV---------VHMKVYDK------------AAQQGI 952
Query: 2179 RGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHG--NSFFYADIMDNTIYRIRPD 2352
RGI + N+K EA++P+S G F V D H ++ ++ D+ N I R + D
Sbjct: 953 RGISLDPNDKM--EALMPVS-------GTSFAVGIDFHAGNDTIYWTDMGFNKISRSKRD 1003
Query: 2353 GEGAAPVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLIT 2532
V+ + ++ DWI+ +Y+ D+ N +EV ++ + R +I+
Sbjct: 1004 QTWKEDVVTNGLGRVEGIAVDWIAGNIYWTDHGFNLIEVARLNGS--------FRYVIIS 1055
Query: 2533 E-LRDPVSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAEN 2709
+ L P S+ VHP KG LF+ E + I + ++DG V+ + + P+ ++ID+ EN
Sbjct: 1056 QGLDQPRSIAVHPEKGYLFWTEWGQIPCIGKAYLDGSEKVVLVSLGIVWPNGISIDYEEN 1115
Query: 2710 RLCWGDTLLKTISCMDFD--GKNVVKLDIDNPIPVAITIMNEYIYYVHQRPY--SIRRVH 2877
+L W D I +D + G + L N ++ + YIY+ + SIRR H
Sbjct: 1116 KLYWCDARTDKIERIDLESGGNREIVLSGSNVDMFSVAVFGAYIYWSDRAHANGSIRRGH 1175
Query: 2878 KKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHP 3057
KN + G +LK N+ + C QLC +
Sbjct: 1176 -KNEATDAVTMRTGLG----INLKEVKVFNRAREKGTNVCAKNNGGCHQLCL------YR 1224
Query: 3058 NELEAKCACRQGFM 3099
+ + CAC G++
Sbjct: 1225 GKAQRTCACAHGYL 1238
Score = 118 bits (296), Expect = 4e-24
Identities = 103/332 (31%), Positives = 130/332 (39%), Gaps = 22/332 (6%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVS---CIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCAD 444
C + C+ Y+ CI CD C D SDEK C + F
Sbjct: 1566 CVTKNSTCNIYSEFECGNGECIDYQLTCDGTAHCKDKSDEKLFYCENRGC--RKGFKPCS 1623
Query: 445 GRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDC 624
R+C +K CDG+ DC D SDE D +AC +FRCAD T CI KS C+ DC
Sbjct: 1624 NRRCISRNKVCDGRNDCGDNSDEIDC---KDSACTSTEFRCADGT-CIGKSAQCNQIIDC 1679
Query: 625 ADGSDEPDTCEFKKC---------TANEFQCKN-KRCQPRKFRCDYYDDCGDNSDEDEC- 771
AD SDE + C C + C + C ++ CD +DCGD +DE +C
Sbjct: 1680 ADASDEKN-CNNTNCAYFYKLGIKSTGFISCNSTSLCILPEWICDGSNDCGDYTDELKCP 1738
Query: 772 --GEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLC-PSLGCQAGCHPS 942
+ C + CP +G CI LCDG KDC DG DE C + C A S
Sbjct: 1739 VQNKPTCEENYFGCP-SGRCILNTWLCDGQKDCEDGVDELHCDSSCSWNQFACSADKCIS 1797
Query: 943 PH---GGECTCPSGYKLDDRFHRTCSDINECAEFGYC--DQLCANHRPGFTCSCLGDCFT 1107
GE C +G D C + C C H + C DC
Sbjct: 1798 KQWTCDGEDDCGNGL---DESDAICGSVTCAVGTFSCLGSHACVPHH--WLCDGERDC-- 1850
Query: 1108 LQMEHGPGKDNLTMRGYCVSNNADKMKLFVAR 1203
G D L+ G C NN F+ R
Sbjct: 1851 -----PNGSDELSTAG-CAPNNTCDENAFMCR 1876
Score = 110 bits (276), Expect = 8e-22
Identities = 71/216 (32%), Positives = 97/216 (44%), Gaps = 10/216 (4%)
Frame = +1
Query: 3094 FMINKENNHSCQKDPAEKIEQLCSSNSTQFQCKNGRCIPKEWKCDGENDCLDESDEIDEK 3273
++ ++E++ Q D E TQF CKNGRCI +W CD ++DC D SDE+
Sbjct: 105 WLCDREDDCGDQTDEMTSCEFPTCEPLTQFICKNGRCISSKWLCDSDDDCGDGSDELG-- 162
Query: 3274 GDKCFHETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPV---CAA 3444
C H C+ + +C N +CIP+ C + P C
Sbjct: 163 ---CIH--SCSADQFRCYN-GRCIPSHWACDGDNDCGDYSDETRTNCTKEETPAPGRCNG 216
Query: 3445 KKFQCD-NHRCIPEQWKXXXXXXXXXXXXEK-----LEMCGNATCAANQFSC-ANGRCIP 3603
K+FQC + C+PE W+ EK L +C T +FSC + GRCI
Sbjct: 217 KEFQCSPDGNCVPELWRCDGEKDCEDGSDEKGCNGTLRLCDEKT----KFSCVSTGRCIS 272
Query: 3604 IYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCAN 3711
WLCDGD DC D +DED C C ++ CAN
Sbjct: 273 KAWLCDGDIDCEDQSDED--NCEGYMCGPPKYPCAN 306
Score = 110 bits (275), Expect = 1e-21
Identities = 83/253 (32%), Positives = 109/253 (42%), Gaps = 13/253 (5%)
Frame = +1
Query: 3670 PPVQCSALQFRCANGRQCVPLRNHXXXXXXXXXXXXXXXXAVTAESCTPDQFKCVSSGLC 3849
PP C A QF+C N ++C+ R SC +QFKC + C
Sbjct: 2 PPQLCKAEQFQC-NNKRCIHDRWRCDGDDDCLDGSDEHADICFNHSCPENQFKC-QNNRC 59
Query: 3850 IPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKCGNGRCILNNWLCDGENDCGDGSD 4029
IP W DE C + R C DQF CGNGRCI +WLCD E+DCGD +D
Sbjct: 60 IPKRWLCDGANDCGNNEDESNKTC-AARTCQFDQFSCGNGRCIPTSWLCDREDDCGDQTD 118
Query: 4030 ESSERGCKTSMNARKC-PFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGGRCARDLCS 4206
E TS C P C+N + CI LCD C G+DE G C CS
Sbjct: 119 E------MTSCEFPTCEPLTQFICKNGR--CISSKWLCDSDDDCGDGSDELG-CIHS-CS 168
Query: 4207 ADRAGCSFKCHNSPNGPICSCPFGEQLVNKTKCEPENECLDSS-----SCSQ-------R 4350
AD+ F+C+N G + + C+ +N+C D S +C++ R
Sbjct: 169 ADQ----FRCYN-----------GRCIPSHWACDGDNDCGDYSDETRTNCTKEETPAPGR 213
Query: 4351 CKDEKHGFTCSCD 4389
C ++ F CS D
Sbjct: 214 CNGKE--FQCSPD 224
Score = 96.7 bits (239), Expect = 2e-17
Identities = 53/149 (35%), Positives = 74/149 (49%), Gaps = 6/149 (4%)
Frame = +1
Query: 478 DGKYDC-----RDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDE 642
DG+ +C R L D+ ++N T +F C + +CI CDG+ C D SDE
Sbjct: 1547 DGRVNCSCRGDRILIDDNRCVTKNSTCNIYSEFECGNG-ECIDYQLTCDGTAHCKDKSDE 1605
Query: 643 P-DTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTG 819
CE + C C N+RC R CD +DCGDNSDE +C + C ++ C G
Sbjct: 1606 KLFYCENRGCRKGFKPCSNRRCISRNKVCDGRNDCGDNSDEIDCKDSACTSTEFRC-ADG 1664
Query: 820 HCIDQLKLCDGSKDCADGADEQQCSQNLC 906
CI + C+ DCAD +DE+ C+ C
Sbjct: 1665 TCIGKSAQCNQIIDCADASDEKNCNNTNC 1693
Score = 67.4 bits (163), Expect = 1e-08
Identities = 61/256 (23%), Positives = 110/256 (42%), Gaps = 17/256 (6%)
Frame = +1
Query: 7717 YALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVDFRN 7896
YA+A++P G+++W+ G ++ IE S++ G R+++V +++ P + VD +
Sbjct: 3071 YAIAVNPKKGMMYWTVIGDRS-------HIEESSMDGTLRRILVQKNLQRPTGLVVDQFS 3123
Query: 7897 QKIYWADVNRLNIEVADYDGQNRKVIASGYRA----KSLDIWDRWLYMSDPLSNGVFRID 8064
Q+++WAD I +DG + V S + +DI++ ++Y + P NG FR+
Sbjct: 3124 QRLFWADFELSVIGSVLFDGSDSVVSVSTKQGLLHPHRIDIFEDYIYGAGP-KNGAFRVH 3182
Query: 8065 KESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLCTVVAD 8244
K S +E + D + +F + N + +C + G C
Sbjct: 3183 KFGRSLVEYLSVDVDKAKSALIFHRYKQMDLPNPCLDLTCEFICLLNPSGASCACP-EGK 3241
Query: 8245 DIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSEPAKECLPP-----------YN 8391
+ Q +DT +L E G +C++ +P C P YN
Sbjct: 3242 SLVNGTCVDQSLLDDTCKLTCENG----GKCII-NEKGDPRCHCWPSYSGERCETNHCYN 3296
Query: 8392 FQCGDGSC--ILLGAT 8433
+ G+C LLGAT
Sbjct: 3297 YCQNGGTCGASLLGAT 3312
Score = 67.0 bits (162), Expect = 1e-08
Identities = 79/345 (22%), Positives = 153/345 (43%), Gaps = 21/345 (6%)
Frame = +1
Query: 2002 KIENPCT-NADCEGMCILSKDNGGFGVGYKCACPIGQKLV-NGKRCIDSIDY---LLFSS 2166
+I + CT + C +C K+N KC+C G KL +G+ CI + + ++FS
Sbjct: 374 EIMDYCTKHLKCSQVCEQHKNN------VKCSCYEGWKLSKDGENCISTDPFEAFIIFSI 427
Query: 2167 NKIVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNS--FFYADIMDNTIYR 2340
+R I + +L ++P G+ + D H + ++ D++++ IYR
Sbjct: 428 RHEIRKIDLHKRDYSL---LVP---------GLRNTIALDFHFSQSLLYWTDVVEDKIYR 475
Query: 2341 IR---PDGEGAAPVLVTHNDGLFS---MSFDWISKQLYYVDNIRNSLEVVKIGETGLVHP 2502
+ G A V+V H GL + ++ DWI+ +Y++D+ + +EV K+
Sbjct: 476 GKLSDTGGVSAIEVIVQH--GLATPEGLTVDWIAGNIYWIDSNLDQIEVAKL-------- 525
Query: 2503 DELVRRQLIT-ELRDPVSVVVHPWKGLLFYA--EAMRPAAIYRCHIDGQNCQVIRN--TT 2667
D +R LI + P ++ + P G+LF+ +A P I + G ++I T
Sbjct: 526 DGTLRTTLIAGAMEHPRAIALDPRYGILFWTDWDANFP-RIESASMSGAERKIIYKDMDT 584
Query: 2668 LGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVKLDIDNPI---PVAITIMNEYIY 2838
P+ + +D E R+ W D I +DG ++++ + P A+++ +Y
Sbjct: 585 GAWPNGLTVDHFEKRIVWTDARSDAIYSALYDGTGMIEIIRGHEYLSHPFAVSLYGSEVY 644
Query: 2839 YVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQP 2973
+ R ++ + +K G ++++ A F L+ QP
Sbjct: 645 WTDWRTNTLAKANKWTGQNVSVIQKTSAQP---FDLQIYHPSRQP 686
Score = 65.1 bits (157), Expect = 5e-08
Identities = 71/288 (24%), Positives = 125/288 (42%), Gaps = 17/288 (5%)
Frame = +1
Query: 2404 MSFDWISKQLYYVDNIR-----------NSLEV-VKIGETGLVHPDELVRRQLITELRDP 2547
++ DWI+ +Y+ D+ R SL + +G+ L P+ R L + +P
Sbjct: 3015 IAVDWIAGNIYWTDHSRMHWFSYYTTHWTSLRYSINVGQ--LNGPN--CTRLLTSIAGEP 3070
Query: 2548 VSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGD 2727
++ V+P KG++++ + I +DG +++ L RP+ + +D RL W D
Sbjct: 3071 YAIAVNPKKGMMYWTVIGDRSHIEESSMDGTLRRILVQKNLQRPTGLVVDQFSQRLFWAD 3130
Query: 2728 TLLKTISCMDFDGK-NVVKLDIDNPI--PVAITIMNEYIYYVHQRPYSIRRVHKKNGGGS 2898
L I + FDG +VV + + P I I +YIY + + RVHK G
Sbjct: 3131 FELSVIGSVLFDGSDSVVSVSTKQGLLHPHRIDIFEDYIYGAGPKNGAF-RVHK---FGR 3186
Query: 2899 KIVREFGAD-ERSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAK 3075
+V D +++ +L ++ +P +PC C +C PS A
Sbjct: 3187 SLVEYLSVDVDKAKSALIFHRYKQMDLP-----NPCLDLTCEFICLLNPS-------GAS 3234
Query: 3076 CACRQGFMINKENNHSCQKDPAEKIEQLCSSNSTQFQCKN-GRCIPKE 3216
CAC +G + N +C ++Q ++ + C+N G+CI E
Sbjct: 3235 CACPEGKSL---VNGTC-------VDQSLLDDTCKLTCENGGKCIINE 3272
Score = 62.0 bits (149), Expect = 4e-07
Identities = 38/111 (34%), Positives = 48/111 (43%), Gaps = 9/111 (8%)
Frame = +1
Query: 607 DGSKDCADGSD----EPDTCEFKKCTAN---EFQCKNKRCQPRKFRCDYYDDCGDNSDED 765
DG +C+ D + + C K T N EF+C N C + CD C D SDE
Sbjct: 1547 DGRVNCSCRGDRILIDDNRCVTKNSTCNIYSEFECGNGECIDYQLTCDGTAHCKDKSDEK 1606
Query: 766 --ECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPS 912
C C G C CI + K+CDG DC D +DE C + C S
Sbjct: 1607 LFYCENRGCRKGFKPCSNR-RCISRNKVCDGRNDCGDNSDEIDCKDSACTS 1656
Score = 39.3 bits (90), Expect = 2.8
Identities = 45/200 (22%), Positives = 68/200 (33%), Gaps = 13/200 (6%)
Frame = +1
Query: 13414 KDTQRTVSGCER---AQCSHLCVSLPSTGFAC-LCPDGIVPQLDGSCA--TQHVEALTMP 13575
KDT V C A LC G C L PD VP S +Q + P
Sbjct: 3507 KDTNDIVCNCTNGKIASTCQLCDGYCYNGGTCQLDPDTNVPVCLCSVGFKSQRCDQKVNP 3566
Query: 13576 KQCKCTNGGKCRL----DGSCECTSDFEGDQCEKESSVSRKIIGTLSENFITVXXXXXXX 13743
C N G C L + C+C++++ G QCE+ + S K + + +
Sbjct: 3567 CDYYCQNEGICTLTAFNEPRCKCSANWSGTQCERPAPKSSKSDNISTRSIAIIVPLVLLV 3626
Query: 13744 XXXXXXXXXXXXNLYKRRQLLFKKNEAADGSVSFHGNVISFSNP---VLENKQDAPGSEF 13914
KRR ++ +G ++ + NP + E D
Sbjct: 3627 TLITTLVIGLFLCKRKRRTKTIRRQPIINGGIN-----VEIGNPSYNMYEVGHDHSEGGL 3681
Query: 13915 NMQQMTSMHDDSTTFTNPVY 13974
T + T ++NPVY
Sbjct: 3682 LASDFTVNAEKPTNYSNPVY 3701
>gi|28573304|ref|NP_788284.1| CG33087-PC [Drosophila melanogaster]
gi|23240381|gb|AAF59114.3| CG33087-PC [Drosophila melanogaster]
Length = 4699
Score = 1446 bits (3743), Expect = 0.0
Identities = 1151/4271 (26%), Positives = 1824/4271 (41%), Gaps = 192/4271 (4%)
Frame = +1
Query: 1426 LAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTNQL- 1602
L +DW++ Y++ + + + V+L L + LDP +G MF+T+
Sbjct: 352 LRLDWLSGNWYLVSEDDGLVYLCTNAMTYCRVILQQVDPLS-SLDLDPTKGFMFYTDWTP 410
Query: 1603 KLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQ 1782
L + +DG+NR LV + S + +D+ + VYW+D D + +DY+G +R + +
Sbjct: 411 SLSRSLLDGSNRTVLVTDQVYHPSSVTLDLANELVYWIDIYKDEVNRVDYEGRNRWTLKR 470
Query: 1783 GMNVVPHPF----GLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISA 1950
++ P P + +F+ +Y W ++ ++KF T +L SN +
Sbjct: 471 PLDS-PVPLKTIHAVEVFENSIYLAAWMDTAIVALDKFSLKTHILQSNVSRGA---NLRI 526
Query: 1951 YHPMAQPGPGQSECLAMKIENPC--TNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNG 2124
+H QP ++ +PC NA C +C+ G KC C G KL N
Sbjct: 527 FHRQKQP----------EVAHPCRDNNAGCNQICVPQWTKGFASA--KCMCTAGYKLHNQ 574
Query: 2125 KRCIDSI--DYLLFSSNKIVR--GIFPEINEKALAEAV--LPISPISQRRIGMYFEVECD 2286
C+ S +L++S + R GI + + E + P + + ++ +
Sbjct: 575 TTCLLSALDKFLVYSDKHLARISGIPLDTEQVQQLEQIGEQPDVMVPVYNVSKTLAIDVN 634
Query: 2287 VHGNSFFYADIMDNTIYRIRPDGEG--------------AAPVLVTHNDGLFSMSFDWIS 2424
V G + FY + D+ P G G + +L + +++FDWI+
Sbjct: 635 VRGKAVFYV-VADSGA---SPFGNGEPSCSIRSQSLNGSVSRLLAQGLKRVHAVAFDWIN 690
Query: 2425 KQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKGLLFYAE--- 2595
LY+ + + + ++ L + D +S+ + P GLL++++
Sbjct: 691 DHLYWTSHKKMQVAPLRNLSKVLTFNTDC----------DAMSLELDPTTGLLYWSQWES 740
Query: 2596 AMRPAAIYRCHIDGQNCQVIRNTTLGRPSE----MAIDFAENRLCWGDTLLKTISCMDFD 2763
A IY +DG + +++ T P + + +D L W D L TI M D
Sbjct: 741 QSCEAGIYSSWMDGTHKELLAKGTSSMPMQWPRSLDVDRRTKELYWCDIRLSTIELMRLD 800
Query: 2764 GKN-VVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERS-- 2934
G V D P +I N IY+ + +I R H S +R+
Sbjct: 801 GTGREVLFKSDQFHPYSIVQNNGLIYWADNKNSTILRFHAHQANLSSTFSSTVHLQRTGR 860
Query: 2935 IFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINKEN 3114
L+ +QP+P C S+C +C TP A C C GF +N
Sbjct: 861 AADLRIFDIASQPLPQTPSA--CAQSKCPGMCLNTPKG-------AICRCPDGFTLNGTG 911
Query: 3115 NHSCQKDPAEKIEQLCSSNSTQFQCKNGR-CIPKEWKCDGENDCLDESDEIDEKGDKCFH 3291
+H + I C+S + C++ R C+ + CDG DC D DE + C
Sbjct: 912 SHCIPQLAPSPIRPNCTSG---YMCRSTRQCLDTKDMCDGFEDCEDGIDESSDPKGPCNV 968
Query: 3292 ETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDG------QKPVCAAKKF 3453
T + C +C + YC DG + C + +F
Sbjct: 969 NTCDKTHNFVCNG--RCYQRSLLCST-----------IPYCSDGTDQANCHQNTCNSNEF 1015
Query: 3454 QCDNH-RCIPEQWKXXXXXXXX--XXXXEKLEMCGNATCAANQFSCANGRCIPIYWLCDG 3624
C RCI W E E + C +F C NGRC +CDG
Sbjct: 1016 TCHKSGRCIQLTWVNDGVVDCGPDDDSDETSETIFASKCP--EFDCNNGRCRQFADVCDG 1073
Query: 3625 DNDCYDGTDE---------DKERCPPVQCSALQFRCANGRQCVPLRNHXXXXXXXXXXXX 3777
++C + DE ++ C P+ C C C+ +
Sbjct: 1074 IDNCGNNADEMECEQECEHGEKYCRPIGCYGEMHMCDGIHDCLDFSDEANCNQTKSDNHP 1133
Query: 3778 XXXXAVTAESCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFK 3957
E C P +F C+ CIP +
Sbjct: 1134 VTEWKELGE-CAPLEFACMFPFECIPDFLR------------------------------ 1162
Query: 3958 CGNGRCILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQ------ETC 4119
CDG + C D +DE + C R E V CE+ + C
Sbjct: 1163 ------------CDGISHCFDKTDEFN---CTHINTTRFDMNETVICEHPDRLCGFSKQC 1207
Query: 4120 IPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCSFKCHNSPNGPICSCPFGEQLV-NK 4296
+ + QLCDGK C TDEG CA LC CS +CHN+P G ICSCP L N
Sbjct: 1208 VTVDQLCDGKNDCEDTTDEGFLCADKLCDRGHE-CSHRCHNTPEGYICSCPDHLYLQPNG 1266
Query: 4297 TKCEPENECLDSSSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRN 4476
+C ++ C +CSQ C+ G+ C C +G++L D+ TCK + + + +NR
Sbjct: 1267 KRCSMQHACDHWDTCSQVCESSGKGYDCRCLDGFDLGFDRFTCK-STAPDEPYVIFTNRQ 1325
Query: 4477 RIYYSDHKLDNWHTFGAIVENAIALAW---DSLTDRIYWSDIREKKILSANRNGT---NA 4638
I + K N F + + N IAL + + IYW+D+ + KI + G N
Sbjct: 1326 DIKGINLKTLNVGNFYSSLRNIIALDFLYNNESNVEIYWTDVIDDKIYRGHLVGESLRNV 1385
Query: 4639 TVFIADGLDITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAV 4818
I GL TEG+A+DWVG+NLYW+DS+L+ IEVA L +RTL+ N+ PR IA+
Sbjct: 1386 EAVIHSGLSTTEGLAVDWVGKNLYWIDSNLDQIEVAKLNGSFRRTLIAG-NMESPRAIAL 1444
Query: 4819 DPRKGVMFWTDWGQN-PCIERASMDGTDRQIIVKT---KIYWPNTIALDYTTDRVYFADS 4986
DPR+G++FWTDW N P IERASM G R++I + WPN + LDYT RVY+ D+
Sbjct: 1445 DPREGLLFWTDWDDNSPRIERASMSGDGRRMISTSWQLSAGWPNGLTLDYTQKRVYWVDA 1504
Query: 4987 KLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTS 5166
K D I YDGS VL + + + HP A+++FE+ +Y++D R + K+ NG+
Sbjct: 1505 KSDSISSTMYDGSEHHVVLRNKEILSHPFAISVFENYVYWTDWRTTSVIRANKW-NGSDV 1563
Query: 5167 EYPSHTFSKALGVVAVHPVLQPVIKNNPCSTNP--CSHLCLLNNKNTFTCKCPMGEKLDA 5340
+ T S+ G+ +H QP +N PC N CSHLCLL+ + TF C+CP +LD
Sbjct: 1564 QVLQRTQSQPFGIQVLHSSRQPWDRN-PCGENNGGCSHLCLLSGRGTFKCECPHVMRLDP 1622
Query: 5341 SGKKCIDDAKPFLVIIQKTNVFGIEMNSASEKETPVLAGMVPLSGLGNAFDAAYDALSEE 5520
+ ++ + L+ + + GI+++ + P + D L +E
Sbjct: 1623 ANERNCVPNEQVLLFVMVDEIRGIDLHQPNHHTIPTI----------RQSPRRIDFLVDE 1672
Query: 5521 MFILEHTNHAKTLAQITTDSAIYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGN 5700
I ++ + + +N N K + AV DW RN+ +
Sbjct: 1673 SRIFWSDIQQNEISSAGISNGLIEPIINT-NIEKPYGFAV---------DWIARNMYFSS 1722
Query: 5701 KITQTIEIIRTQGKQYRSVILSNDQSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVA 5880
+ + ++ S+I + G ++W+ + +++
Sbjct: 1723 GQIKCNILASNLKGEFASIIHED------LNMVDSIVLDPANGKMYWIHSASDGSMSQLE 1776
Query: 5881 RAGLDGSNPLVIASNDLAELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGG 6060
++ LDGS+ +I ++ L + +D + R+Y++ +G + R +++
Sbjct: 1777 QSNLDGSSRSLIYQHE-NNLQSLTMDFDSQRLYYAYDNSGIAYYDIPRNETRKVLVASPI 1835
Query: 6061 RQPNGLAFYGDRLFYADSAFDSIEVATINGDSQPPQWTHFKKDVENLANIKALQPRASSS 6240
+ L Y L++ ++ I S ++ + + +++ ++K A +
Sbjct: 1836 TSISSLTVYNGTLYFPENIQSVIMQCEKEACSN---MSYLRVNTKSIQSMKMFYADAQTG 1892
Query: 6241 GHPCH--INNGNCDHICIPLMFAQRTCTCANGY--VKDGQTSCKLFDESF---VIVATKT 6399
+ C G C +C+ C CA GY + T C E + V
Sbjct: 1893 SNTCAEWAYRGGCQQLCLATSSIDHVCRCALGYDVEPNNPTGCVPRAEFIFYSIDVLQGV 1952
Query: 6400 KVIGYPIDETQSKGVAMEPIGGLSITG-VDYDYESKTIYVAEASGINKGITAYTIGESSP 6576
++I P ++ + A+ PI +S +DY + T+Y + G + + +
Sbjct: 1953 EMID-PSEQFDTPSPALVPISRVSSASFIDYLANTDTLYWGDNE---LGSISRVKRDGTQ 2008
Query: 6577 RAVIRDSIGSLTIKS------LAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTK 6738
R I +++ + K +AIDW+ N+Y+ D +R IEV++LDG++R ++++
Sbjct: 2009 RETILEALNLVGYKQQDWLGGIAIDWVAGNIYW--SDTKRNIIEVARLDGSHRYVVVSN- 2065
Query: 6739 TETPSSIAVDPVSRYLYWADQGQKPTIQRSFLDGSRREVIVSSGIAEPT--DLVVDVASK 6912
E P+++AVDP+ L++ Q I R LDGS+ V+V+ A LV+D+ +
Sbjct: 2066 LEKPTALAVDPLQGLLFYVTQQH---IGRVGLDGSQPFVLVNQTRANWAVGSLVLDIEAT 2122
Query: 6913 MIYWSDAKMDGIYRVRSTGGTPE-LVRSDIASAAGVALHGQNMYWTDNRL-EKLFRATSK 7086
+YW + D + +V G E L+ + + +A G +YW +N+ E + R
Sbjct: 2123 KVYWCERYPDALMKVDYDGNLREQLLNESLNNPVALAKMGDYLYWAENKYNEGIIRVAPL 2182
Query: 7087 PNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRASSPCQITDNLRKSPCTQLCFATPGTQ 7266
N L S + I D+ ++S + Q R S+PC ++ C QLC +
Sbjct: 2183 AN---LSQSKVVLQTEQDAIRDLKIYSKHLQ-RGSNPCAHSNGA----CEQLCLFNGTSA 2234
Query: 7267 TPTCSCARGVLKGRTCEEPDTYIMFSDGDKIIDVAIEPDVKASRPLKDPFPEISNLQTFD 7446
C+ +R G +CE + +++FS I + + + P++ ISN
Sbjct: 2235 VCACAHSRLASDGYSCEPYENFLLFSYRSNIESIHMTDHADKNWPVQ----MISN----- 2285
Query: 7447 VDVNLRRVYFVVESPVGVNISWFSMNNAENPRLVF--GASKQPHAKEIRHISDMKLDWLT 7620
+L R + + ++S V G + ++ + + + D +
Sbjct: 2286 --TSLMRNVIAITYNYEEQLVYYSDVQLSTINQVHFNGTGHRVLLEQQQRVEGLAYDIVN 2343
Query: 7621 QKIYFTTGRGGKVMAIDTAGEHLS--------------TIASGDWTYALAIDPCSGLLFW 7758
+++++T+ + +++ HLS ++ D +A++PC G+++W
Sbjct: 2344 EQLFWTSNNNATIRSVEL--RHLSEHADQNQVHVKKVLSLREDDKPRGIAVEPCLGMIYW 2401
Query: 7759 SDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVDFRNQKIYWADVNRLNIE 7938
T+ P I+RS L G +VI+ I +P A+ +D QK+YWAD IE
Sbjct: 2402 ------TNWNEGSPCIQRSYLTGYGTEVIIKTDIKMPNALTLDLEQQKLYWADARLDKIE 2455
Query: 7939 VADYDGQNRKVIASGY--RAKSLDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVSDRRI 8112
+YDG NR V+A A ++ ++ L+ +D + + V R +K +G+ + +
Sbjct: 2456 RTNYDGSNRVVLAHSTPKHAFAMAVYGDLLFWTDWVLHAVVRANKYTGTDVLFLREHVTR 2515
Query: 8113 PGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLCTVVADDIGLAASKVQCSCNDT 8292
P + V +N N +Q CK NG C+ +C + + + C C
Sbjct: 2516 PMGI--------VAVQNTSINCDANQ-CKILNGQCEDVCILNK------SGQATCHC--- 2557
Query: 8293 YELVQEPGKDYPTQCVLRGSNSEPAKECLPPYNFQCG-------DGSCILLGATCDSKPD 8451
TQ VL + + C+ P N CG G CI L TCD+
Sbjct: 2558 ------------TQGVL----APDGRRCIAPVNTSCGLSQYNCHSGECIPLELTCDNVTH 2601
Query: 8452 CADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHIDDCGDGSDELDCPSAVACAE- 8628
CAD SDE +YC R CPE + +C N RCI KC+ CGDGSDE P C
Sbjct: 2602 CADGSDEFRSYCIFRQCPETHFMCQNHRCIPKEHKCDGEQQCGDGSDET--PLLCKCQSE 2659
Query: 8629 ---------------GTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPGLPIDCRG 8763
F C +G CI + +CD DC D SDE + C +P +
Sbjct: 2660 DIDMHPSNNNTKEMPDMFRCGSGECIPRKFLCDSLKDCRD--FSDEKM--CAPIPCEKND 2715
Query: 8764 VK-VRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQ---QCAQHYVRCPSGRCIPET 8931
+ V C N+ ICI P CDG DC D DE L C N C RC SG CI +
Sbjct: 2716 MTFVHCGNSTICIMPRWRCDGDPDCPDGTDE--LDCANHTSLSCDPGQFRCASGNCIAGS 2773
Query: 8932 WQCDGDNDCSDGWDETH--TNCTDT--AGKKICVGDYLFQCDNLKCISRAFIXXXXXXXX 9099
W CDG+ DC DG DE + T C A K C+ +QCD
Sbjct: 2774 WHCDGEKDCPDGSDEINCRTECRHNQFACDKTCI-PASWQCDG--------------KSD 2818
Query: 9100 XXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGG------ED 9261
C NR C F C S+ + CIP+ W+CDG+ C G ED
Sbjct: 2819 CEDGSDEGPQCPNRPCRPHLFQCKSSGR-------CIPQKWVCDGEKDCPSGLGDEGSED 2871
Query: 9262 ESTELCKTEK-KECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYS----SCQP 9426
E + +C C++ CI S + CDGD DC G DE+ C + SC
Sbjct: 2872 EGPQCGGVAHIPDCPPPAHLCTSGLCIDSHYVCDGDEDCPGGDDEYEGCVPAFQPHSCPG 2931
Query: 9427 D--FFQCANHKCVPNSWKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTSGECI 9600
QC + C+ + CDG DC DGSDE +S A F+C +G CI
Sbjct: 2932 GSLMHQCQDGLCIFKNQTCDGKPDCGDGSDET----SSLCAHTRGCNGTDDFRCKNGACI 2987
Query: 9601 DDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISD 9780
+CDR DC D SDE LC ++EC + + +CE +C D +GY+C C G+ +
Sbjct: 2988 HADLLCDRRNDCADFSDEE-LCNVNECLIPD--ICEHECEDKVVGYQCHCRPGYKVLPKS 3044
Query: 9781 QKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLAN 9960
C +++EC E CSQ C + GSYKC C GY L D H+CK T + +N
Sbjct: 3045 PHLCTDIDECDEQ-QPCSQTCINTYGSYKCLCAKGYALV-DHHTCKATS-NVSMELIFSN 3101
Query: 9961 KHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLID-QGKLRLLRVDLDEMDSPLS 10137
++YIR++ + GN L + N V+LD D + Y D + ++ + + +
Sbjct: 3102 RYYIRQVDMTGNGSILINE-LSNAVALDYDWDSQCLYWSDVTSTVGTIKRYCPKENKTQT 3160
Query: 10138 SYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIV 10317
++ +L++ +G+AVDWV + LY ++ +I V +LDG++ K LI + +++P+ I
Sbjct: 3161 LHQAMLKN----PDGLAVDWVAKNLYWCDKGLDTIEVSQLDGKYRKVLINEYLREPRGIA 3216
Query: 10318 VHPGKGYLFFTEWSLQPYIGRIALDGS-PELQDPIFKLAEHDLGWPNAIAIDYFSDRLFW 10494
+HP + ++F+++W P+IG+ +DGS P++ + LGWPNA+ I + + +LFW
Sbjct: 3217 LHPYQQHIFWSDWGDSPHIGKAGMDGSNPKM------IIRDGLGWPNALTISFETQQLFW 3270
Query: 10495 GDAHLNEIGFMDFDGNGRRHI------PAQRTSHVSSMVVFDDYLYWADWNLREVLRCDK 10656
GDA + I D DGN R + P H+ ++ V++ ++YW+DW + + C
Sbjct: 3271 GDAREDTISVSDLDGNHTRLLLARSINPLLNLHHIFAIAVWEGHIYWSDWETKSIEYCSI 3330
Query: 10657 WTGKNETILKKTVQLPNDLRIVHPMR--QPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSC 10830
+ G+N T L T+ P DLR+ HP R QP NPC N CS LC++ Y C C
Sbjct: 3331 FNGQNCTTLITTIHRPMDLRVFHPYRQQQPMSGNPCLAAN--CSTLCVLSPEEPYYKCMC 3388
Query: 10831 PDQFVLLSDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRI 11010
P F+L D +TC NCT F C + KCIP W CD + DC DGSDEP C
Sbjct: 3389 PTNFILADDGRTCRANCTAAHFEC-VNTYKCIPFYWRCDTQDDCGDGSDEP--ETCPPFH 3445
Query: 11011 CPVGEFQCTNHNCTRPFQIXXXXXXXXXXXXEQNCDK-ACDPWMFKCAATGR----CIPR 11175
C G++QC N CT P + E NCDK C KC AT C+
Sbjct: 3446 CEPGQYQCANKKCTHPSNLCDGINQCGDGSDELNCDKFTCFDNHMKCGATANSSAFCVDN 3505
Query: 11176 RFTXXXXXXXXXRSDEADTLCMSAERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXET 11355
DE+ + C ++F+C NN+C+ W E
Sbjct: 3506 VKRCDGVKDCPGGEDESACTPLV----CKKDQFQCGNNRCMPFVWVCDGDIDCPDKSDEA 3561
Query: 11356 PECAQIECKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDK---QRCPTCDDVGEFRCA 11526
C + C +C S RCIP C+ DC + DE TCD F+C
Sbjct: 3562 -NCDNVSCGPNDFQCDSG-RCIPLAWRCDDDHDCPNGEDEPASCFSSKATCDPT-YFKCN 3618
Query: 11527 TSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQ 11706
S KCIP RW CD ENDCGD SDEL+ R CSESEFRC GKCI + CDG I
Sbjct: 3619 NS-KCIPGRWRCDYENDCGDGSDELNCQ----MRNCSESEFRCGTGKCIKHNYRCDGEIH 3673
Query: 11707 CSDGLDESQCTLRRCLPGHRQCDD-GTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCSP 11883
C D DE C + C +C TCI + CD DCP+ +DE++C TC
Sbjct: 3674 CDDNSDEINCNI-TCKENQFKCAAFNTCINKQYKCDGDDDCPDGSDEVNC------TCHS 3726
Query: 11884 FEFECANSVCIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLC 12063
F C N CI ++ SDE+ C C F+C ++LC+ LC
Sbjct: 3727 DHFSCGNGKCIMSRWKCDGWDDCLDGSDESLETCAKTHCHAN-AFKC-RNQLCVRNSALC 3784
Query: 12064 NGFNDCGPNDFSDEHLSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEI 12243
+G NDCG N+ DE ++C++ + C DQF+C N C++ CD + +C D SDE+
Sbjct: 3785 DGINDCGENE--DESDAVCAALPK---CRHDQFQCENDDCISKAFRCDGQYNCVDGSDEM 3839
Query: 12244 GCSKHGGKTSCEAFGNNGGCKHICTDVRDGFY-CHCRDGFRPDPQSPKECIDIDECAGNN 12420
C G C IC + + G Y C C DG+ P+ C+ +G +
Sbjct: 3840 NCQ--------PPVCGFGSCSQICIEKKAGHYNCKCADGYHKGPEKNATCL----ASGPD 3887
Query: 12421 TCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGS 12600
L + ++ + E VVG ++ I D L++
Sbjct: 3888 QILLLASEQEFRFILPAKQ--EGTTVVGFF---------QTDSLKIDVFDILIR------ 3930
Query: 12601 GTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDF 12780
P+ L++WID ++ IA + G ++ D
Sbjct: 3931 -----------------------PKDTLLFWIDSHHGKVHTMKIATPHVEGTGVRVRRDL 3967
Query: 12781 AAMGVV-------PTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIF 12939
+ P ++AVD+ + ++I ID+++ +
Sbjct: 3968 KELTAFNIPELDDPKSLAVDWISQRVYI----------------------IDSRHNQILA 4005
Query: 12940 VCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDL 13119
+ +Y+ + G PT ++ P + + +S L I A +DG++++ +V+
Sbjct: 4006 TDIEGKKYISLVSTG--MNPTDIVLEPESRIMIWST--LENGILVASLDGSNKKSLVERD 4061
Query: 13120 VFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTV--VHDRHIPYAVDVFENHIY 13293
V P S+++D G R+YW D + ++ ++G +R V +R P +DVFE+++Y
Sbjct: 4062 VGWPISLSMDYPTG-RLYWADYRKGTIETCRLNGKDRNVVRRFGNREKPQKIDVFEDYLY 4120
Query: 13294 WLSRESKTLYVQDKFGRGRVSVL-----ASDLEDGHTVRVSQKYAKDTQRTVSGCERAQC 13458
+ +++ +KFG + L +SD+ H ++ ++ + + RA C
Sbjct: 4121 -IKLYDQSIIKMNKFGNDNGTYLLKGYRSSDIGILHPMKQNRNISNPCAKDPCKSSRALC 4179
Query: 13459 SHLCVSLPSTGFACLCPDGIVPQLDGSCATQHVEALTMPKQCKCTNGGKCRLDG---SCE 13629
+ S S G++C C +G V DG C P QC N G C++ C
Sbjct: 4180 --ILSSESSVGYSCKCAEGYVMTDDGVCKAHADIPDYCPLQC---NLGTCKIVDHVPKCI 4234
Query: 13630 CTSDFEGDQCE 13662
C FEG+ CE
Sbjct: 4235 CQPQFEGELCE 4245
Score = 454 bits (1169), Expect = e-125
Identities = 407/1593 (25%), Positives = 668/1593 (41%), Gaps = 147/1593 (9%)
Frame = +1
Query: 1018 NECAEFGY---CDQLC-ANHRPGFTCSC-LGDCFTLQMEHGPGKDNLTMRGYCVSNNADK 1182
N CAE+ Y C QLC A C C LG + ++ + G CV A+
Sbjct: 1894 NTCAEWAYRGGCQQLCLATSSIDHVCRCALG--YDVEPNNPTG---------CVPR-AEF 1941
Query: 1183 MKLFVARREGLYRLNPKNPDEE-------VKKLASGEFIYGIDFDYGDRKIFWTDRLAHS 1341
+ + +G+ ++P + + +++S FI D+ ++W D S
Sbjct: 1942 IFYSIDVLQGVEMIDPSEQFDTPSPALVPISRVSSASFI---DYLANTDTLYWGDNELGS 1998
Query: 1342 AFSADVDDEGEISQIKKLSL---KSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGER 1512
D + ++ L+L K + +A+DW+ +Y ++ I+V+ DG
Sbjct: 1999 ISRVKRDGTQRETILEALNLVGYKQQDWLGGIAIDWVAGNIYWSDTKRNIIEVARLDGSH 2058
Query: 1513 RTVLLADGLTLPLDIALDPLRGEMFFTNQLKLEAAAMDGTNRRTLVNTHTHQ--VSGIVV 1686
R V++++ L P +A+DPL+G +F+ Q + +DG+ LVN V +V+
Sbjct: 2059 RYVVVSN-LEKPTALAVDPLQGLLFYVTQQHIGRVGLDGSQPFVLVNQTRANWAVGSLVL 2117
Query: 1687 DITAKRVYWVDPKVDRLESIDYQGNDR-RIVAQGMNVVPHPFGLALFDQYLYWTDWT-RL 1860
DI A +VYW + D L +DY GN R +++ + +N +P LA YLYW +
Sbjct: 2118 DIEATKVYWCERYPDALMKVDYDGNLREQLLNESLN---NPVALAKMGDYLYWAENKYNE 2174
Query: 1861 GVIQVEKFG--SDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPC--TNA 2028
G+I+V S +K++ ++ + + I + H + NPC +N
Sbjct: 2175 GIIRVAPLANLSQSKVVLQTEQDAIRDLKIYSKH-------------LQRGSNPCAHSNG 2221
Query: 2029 DCEGMCILSKDNGGFGVGYKCACPIGQKLVNGKRCIDSIDYLLFSSNKIVRGIFPEINEK 2208
CE +C+ + G CAC + +G C ++LLFS R I+
Sbjct: 2222 ACEQLCLFN------GTSAVCACAHSRLASDGYSCEPYENFLLFS----YRSNIESIHMT 2271
Query: 2209 ALAEAVLPISPISQRRIGM-YFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTH 2385
A+ P+ IS + + + +Y+D+ +TI ++ +G G VL+
Sbjct: 2272 DHADKNWPVQMISNTSLMRNVIAITYNYEEQLVYYSDVQLSTINQVHFNGTGHR-VLLEQ 2330
Query: 2386 NDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRD---PVSV 2556
+ +++D +++QL++ N ++ V++ V + + LR+ P +
Sbjct: 2331 QQRVEGLAYDIVNEQLFWTSNNNATIRSVELRHLSEHADQNQVHVKKVLSLREDDKPRGI 2390
Query: 2557 VVHPWKGLLFYAEAMRPA-AIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTL 2733
V P G++++ + I R ++ G +VI T + P+ + +D + +L W D
Sbjct: 2391 AVEPCLGMIYWTNWNEGSPCIQRSYLTGYGTEVIIKTDIKMPNALTLDLEQQKLYWADAR 2450
Query: 2734 LKTISCMDFDGKNVVKLDIDNPIPV-AITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVR 2910
L I ++DG N V L P A+ + + +++ +++ R +K G +R
Sbjct: 2451 LDKIERTNYDGSNRVVLAHSTPKHAFAMAVYGDLLFWTDWVLHAVVRANKYTGTDVLFLR 2510
Query: 2911 EFGADERSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQ 3090
E I ++ QN I D+ + QC +C S +A C C Q
Sbjct: 2511 EHVTRPMGIVAV-----QNTSINCDANQCKILNGQCEDVCILNKSG------QATCHCTQ 2559
Query: 3091 GFM----------------INKENNHSCQ--------------KDPAEKIEQLC---SSN 3171
G + +++ N HS + D +++ C
Sbjct: 2560 GVLAPDGRRCIAPVNTSCGLSQYNCHSGECIPLELTCDNVTHCADGSDEFRSYCIFRQCP 2619
Query: 3172 STQFQCKNGRCIPKEWKCDGENDCLDESDEID-----EKGDKCFHET------------- 3297
T F C+N RCIPKE KCDGE C D SDE + D H +
Sbjct: 2620 ETHFMCQNHRCIPKEHKCDGEQQCGDGSDETPLLCKCQSEDIDMHPSNNNTKEMPDMFRC 2679
Query: 3298 ---ECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNH 3468
EC C + K C +C G +C +++CD
Sbjct: 2680 GSGECIPRKFLCDSLKDCRDFSDEKMCAPIPCEKNDMTFVHC--GNSTICIMPRWRCDGD 2737
Query: 3469 RCIPEQWKXXXXXXXXXXXXEKLEMCGNAT---CAANQFSCANGRCIPIYWLCDGDNDCY 3639
P+ ++L+ C N T C QF CA+G CI W CDG+ DC
Sbjct: 2738 PDCPD-------------GTDELD-CANHTSLSCDPGQFRCASGNCIAGSWHCDGEKDCP 2783
Query: 3640 DGTDEDKERCPPVQCSALQFRCANGRQCVPLRNHXXXXXXXXXXXXXXXXAVTAESCTPD 3819
DG+DE R +C QF C + C+P + C P
Sbjct: 2784 DGSDEINCR---TECRHNQFAC--DKTCIP-ASWQCDGKSDCEDGSDEGPQCPNRPCRPH 2837
Query: 3820 QFKCVSSGLCIPASW-----KXXXXXXXXXXSDE--PKFGCTSG-RQCSSDQFKCGNGRC 3975
F+C SSG CIP W K S++ P+ G + C C +G C
Sbjct: 2838 LFQCKSSGRCIPQKWVCDGEKDCPSGLGDEGSEDEGPQCGGVAHIPDCPPPAHLCTSGLC 2897
Query: 3976 ILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDGKTH 4155
I ++++CDG+ DC G DE GC + CP + + CI +Q CDGK
Sbjct: 2898 IDSHYVCDGDEDCPGGDDE--YEGCVPAFQPHSCPGGSLMHQCQDGLCIFKNQTCDGKPD 2955
Query: 4156 CPGGTDE--------------------GGRCA-----------------RDLCSADRA-- 4218
C G+DE G C +LC+ +
Sbjct: 2956 CGDGSDETSSLCAHTRGCNGTDDFRCKNGACIHADLLCDRRNDCADFSDEELCNVNECLI 3015
Query: 4219 --GCSFKCHNSPNGPICSCPFGEQLVNKTK--CEPENECLDSSSCSQRCKDEKHGFTCSC 4386
C +C + G C C G +++ K+ C +EC + CSQ C + + C C
Sbjct: 3016 PDICEHECEDKVVGYQCHCRPGYKVLPKSPHLCTDIDECDEQQPCSQTCINTYGSYKCLC 3075
Query: 4387 DEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGAIVENAIALAWDSL 4566
+GY L VD TCK NV I+ SNR I D N + NA+AL +D
Sbjct: 3076 AKGYAL-VDHHTCKATSNVSMELIF-SNRYYIRQVD-MTGNGSILINELSNAVALDYDWD 3132
Query: 4567 TDRIYWSDIREK----KILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVDSSLNT 4734
+ +YWSD+ K N T T+ A L +G+A+DWV +NLYW D L+T
Sbjct: 3133 SQCLYWSDVTSTVGTIKRYCPKENKTQ-TLHQA-MLKNPDGLAVDWVAKNLYWCDKGLDT 3190
Query: 4735 IEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQNPCIERASMDGTDRQIIV 4914
IEV+ L D K R +L+++ + +PRGIA+ P + +FW+DWG +P I +A MDG++ ++I+
Sbjct: 3191 IEVSQL-DGKYRKVLINEYLREPRGIALHPYQQHIFWSDWGDSPHIGKAGMDGSNPKMII 3249
Query: 4915 KTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASS----KFVQHPHALA 5082
+ + WPN + + + T ++++ D++ D I + DG+ +LA S + H A+A
Sbjct: 3250 RDGLGWPNALTISFETQQLFWGDAREDTISVSDLDGNHTRLLLARSINPLLNLHHIFAIA 3309
Query: 5083 IFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPV-LQPVIKNNPCST 5259
++E +Y+SD + ++ Y NG T + + + HP Q + NPC
Sbjct: 3310 VWEGHIYWSDWETKSIE-YCSIFNGQNCTTLITTIHRPMDLRVFHPYRQQQPMSGNPCLA 3368
Query: 5260 NPCSHLCLLNNKNT-FTCKCPMGEKLDASGKKC 5355
CS LC+L+ + + C CP L G+ C
Sbjct: 3369 ANCSTLCVLSPEEPYYKCMCPTNFILADDGRTC 3401
Score = 296 bits (758), Expect = 1e-77
Identities = 271/1020 (26%), Positives = 423/1020 (40%), Gaps = 90/1020 (8%)
Frame = +1
Query: 337 YQR---CDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLS 507
YQR C I C+DG+D+ +C +T C+S N F C +C ++ DG DC
Sbjct: 984 YQRSLLCSTIPYCSDGTDQANCHQNT--CNS-NEFTCHKSGRCIQLTWVNDGVVDCGP-D 1039
Query: 508 DEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQ 687
D+ D S A +F C + +C Q + VCDG +C + +DE + CE ++C E
Sbjct: 1040 DDSDETSETIFASKCPEFDC-NNGRCRQFADVCDGIDNCGNNADEME-CE-QECEHGEKY 1096
Query: 688 CKNKRCQPRKFRCDYYDDCGDNSDEDECGE---------------------------YRC 786
C+ C CD DC D SDE C + + C
Sbjct: 1097 CRPIGCYGEMHMCDGIHDCLDFSDEANCNQTKSDNHPVTEWKELGECAPLEFACMFPFEC 1156
Query: 787 PPGKWNCPGTGHCIDQL--------------------------------------KLCDG 852
P C G HC D+ +LCDG
Sbjct: 1157 IPDFLRCDGISHCFDKTDEFNCTHINTTRFDMNETVICEHPDRLCGFSKQCVTVDQLCDG 1216
Query: 853 SKDCADGADEQ-QCSQNLCP-SLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINEC 1026
DC D DE C+ LC C CH +P G C+CP L R CS + C
Sbjct: 1217 KNDCEDTTDEGFLCADKLCDRGHECSHRCHNTPEGYICSCPDHLYLQPNGKR-CSMQHAC 1275
Query: 1027 AEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARR 1206
+ C Q+C + G+ C CL D F L + K Y + N +K
Sbjct: 1276 DHWDTCSQVCESSGKGYDCRCL-DGFDLGFDRFTCKSTAPDEPYVIFTNRQDIKGI---- 1330
Query: 1207 EGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQI 1386
L LN N ++ + + +F+Y + + +I+WTD + + + E + +
Sbjct: 1331 -NLKTLNVGNFYSSLRNIIALDFLYNNESNV---EIYWTDVIDDKIYRGHLVGES-LRNV 1385
Query: 1387 KKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALD 1566
+ + L LAVDW+ LY I+S +I+V+ +G R L+A + P IALD
Sbjct: 1386 EAVIHSGLSTTEGLAVDWVGKNLYWIDSNLDQIEVAKLNGSFRRTLIAGNMESPRAIALD 1445
Query: 1567 PLRGEMFFT----NQLKLEAAAMDGTNRRTLVNTHTHQV---SGIVVDITAKRVYWVDPK 1725
P G +F+T N ++E A+M G RR + + +G+ +D T KRVYWVD K
Sbjct: 1446 PREGLLFWTDWDDNSPRIERASMSGDGRRMISTSWQLSAGWPNGLTLDYTQKRVYWVDAK 1505
Query: 1726 VDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKF-GSDTKL 1902
D + S Y G++ +V + ++ HPF +++F+ Y+YWTDW VI+ K+ GSD ++
Sbjct: 1506 SDSISSTMYDGSEHHVVLRNKEILSHPFAISVFENYVYWTDWRTTSVIRANKWNGSDVQV 1565
Query: 1903 LWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPC--TNADCEGMCILSKDNGGFG 2076
L T++ P GI H QP NPC N C +C+LS G G
Sbjct: 1566 L-QRTQSQ--PFGIQVLHSSRQPWD----------RNPCGENNGGCSHLCLLS----GRG 1608
Query: 2077 VGYKCACPIGQKL--VNGKRCIDSIDYLLFSSNKIVRGIFPEINEKALAEAVLPISPISQ 2250
+KC CP +L N + C+ + LLF +RGI ++++ +P S
Sbjct: 1609 T-FKCECPHVMRLDPANERNCVPNEQVLLFVMVDEIRGI--DLHQP--NHHTIPTIRQSP 1663
Query: 2251 RRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWISKQ 2430
RRI V + F++DI N I P++ T+ + + + DWI++
Sbjct: 1664 RRIDFL------VDESRIFWSDIQQNEISSAGISNGLIEPIINTNIEKPYGFAVDWIARN 1717
Query: 2431 LYYVD-NIR-NSLEVVKIGE-TGLVHPDELVRRQLITELRDPVSVVVHPWKGLLFYAEAM 2601
+Y+ I+ N L GE ++H D L S+V+ P G +++ +
Sbjct: 1718 MYFSSGQIKCNILASNLKGEFASIIHED----------LNMVDSIVLDPANGKMYWIHSA 1767
Query: 2602 RPAA---IYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKN 2772
+ + + ++DG + +I S + +DF RL + I+ D
Sbjct: 1768 SDGSMSQLEQSNLDGSSRSLIYQHENNLQS-LTMDFDSQRLYYAYD-NSGIAYYDIPRNE 1825
Query: 2773 VVKLDIDNPIP--VAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSL 2946
K+ + +PI ++T+ N +Y+ I + K+ +R + +SI S+
Sbjct: 1826 TRKVLVASPITSISSLTVYNGTLYFPENIQSVIMQCEKEACSNMSYLR---VNTKSIQSM 1882
Query: 2947 KACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINKENNHSC 3126
K Q + E R C QLC AT S H C C G+ + N C
Sbjct: 1883 KMFYADAQTGSNTCAEWAYRGG-CQQLCLATSSIDH------VCRCALGYDVEPNNPTGC 1935
Score = 243 bits (620), Expect = 1e-61
Identities = 195/699 (27%), Positives = 306/699 (42%), Gaps = 30/699 (4%)
Frame = +1
Query: 127 SASVNTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDT- 303
S N + C NDF+C+ G+CI W C S + CD
Sbjct: 3558 SDEANCDNVSCGPNDFQCDSGRCIPLAWRCDDDHDCPNGEDEPAS----CFSSKATCDPT 3613
Query: 304 -YTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCD 480
+ ++ CI RCD DC DGSDE +C S++ F C G+ C + +CD
Sbjct: 3614 YFKCNNSKCIPGRWRCDYENDCGDGSDELNCQMRNC---SESEFRCGTGK-CIKHNYRCD 3669
Query: 481 GKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEF 660
G+ C D SDE + + C + QF+CA CI K + CDG DC DGSDE +
Sbjct: 3670 GEIHCDDNSDEINC----NITCKENQFKCAAFNTCINKQYKCDGDDDCPDGSDEVNC--- 3722
Query: 661 KKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDE--DECGEYRCPPGKWNCPGTGHCIDQ 834
C ++ F C N +C +++CD +DDC D SDE + C + C + C C+
Sbjct: 3723 -TCHSDHFSCGNGKCIMSRWKCDGWDDCLDGSDESLETCAKTHCHANAFKCRNQ-LCVRN 3780
Query: 835 LKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRT-CS 1011
LCDG DC + DE S +C +L +C ++ D +++ S
Sbjct: 3781 SALCDGINDCGENEDE---SDAVCAALPKCRHDQFQCENDDC-ISKAFRCDGQYNCVDGS 3836
Query: 1012 DINEC----AEFGYCDQLCANHRPG-FTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNA 1176
D C FG C Q+C + G + C C GP K+ C+++
Sbjct: 3837 DEMNCQPPVCGFGSCSQICIEKKAGHYNCKCADG-----YHKGPEKN-----ATCLASGP 3886
Query: 1177 DKMKLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDY----GDRKIFWTDR---LA 1335
D++ L + +E + L K V + + FD D +FW D
Sbjct: 3887 DQILLLASEQEFRFILPAKQEGTTVVGFFQTDSLKIDVFDILIRPKDTLLFWIDSHHGKV 3946
Query: 1336 HSAFSADVDDEG-------EISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVS 1494
H+ A EG ++ ++ ++ L P+ LAVDWI+ +YII+S +I +
Sbjct: 3947 HTMKIATPHVEGTGVRVRRDLKELTAFNIPELDDPKSLAVDWISQRVYIIDSRHNQILAT 4006
Query: 1495 SYDGERRTVLLADGLTLPLDIALDP-LRGEMFFTNQLKLEAAAMDGTNRRTLVNTHTHQV 1671
+G++ L++ G+ P DI L+P R ++ T + + A++DG+N+++LV
Sbjct: 4007 DIEGKKYISLVSTGMN-PTDIVLEPESRIMIWSTLENGILVASLDGSNKKSLVERDVGWP 4065
Query: 1672 SGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDW 1851
+ +D R+YW D + +E+ G DR +V + N P + +F+ YLY +
Sbjct: 4066 ISLSMDYPTGRLYWADYRKGTIETCRLNGKDRNVVRRFGN-REKPQKIDVFEDYLYIKLY 4124
Query: 1852 TRLGVIQVEKFGSD--TKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTN 2025
+ +I++ KFG+D T LL ++ I HPM Q I NPC
Sbjct: 4125 DQ-SIIKMNKFGNDNGTYLLKGYRSSD-----IGILHPMKQ---------NRNISNPCAK 4169
Query: 2026 ADCE---GMCILSKDNGGFGVGYKCACPIGQKLVNGKRC 2133
C+ +CILS ++ VGY C C G + + C
Sbjct: 4170 DPCKSSRALCILSSES---SVGYSCKCAEGYVMTDDGVC 4205
Score = 242 bits (618), Expect = 2e-61
Identities = 189/700 (27%), Positives = 290/700 (41%), Gaps = 35/700 (5%)
Frame = +1
Query: 139 NTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHS 318
N S C+ FRC G CI W C+ +Q+ CD
Sbjct: 2751 NHTSLSCDPGQFRCASGNCIAGSWHCDGEKDCPDGSDEINC-RTECRHNQFACDK----- 2804
Query: 319 VSCIAEYQRCDNITDCADGSDE-KDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDC 495
+CI +CD +DC DGSDE CP ++F C +C CDG+ DC
Sbjct: 2805 -TCIPASWQCDGKSDCEDGSDEGPQCPNRPC---RPHLFQCKSSGRCIPQKWVCDGEKDC 2860
Query: 496 ------RDLSDEKDSCSR-NHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTC 654
DE C H CI +VCDG +DC G DE + C
Sbjct: 2861 PSGLGDEGSEDEGPQCGGVAHIPDCPPPAHLCTSGLCIDSHYVCDGDEDCPGGDDEYEGC 2920
Query: 655 ----EFKKCTANEF--QCKNKRCQPRKFRCDYYDDCGDNSDEDE--CGEYRCPPGKWNCP 810
+ C QC++ C + CD DCGD SDE C R C
Sbjct: 2921 VPAFQPHSCPGGSLMHQCQDGLCIFKNQTCDGKPDCGDGSDETSSLCAHTR------GCN 2974
Query: 811 GT-------GHCIDQLKLCDGSKDCADGADEQQCSQNLC--PSLGCQAGCHPSPHGGECT 963
GT G CI LCD DCAD +DE+ C+ N C P + C+ C G +C
Sbjct: 2975 GTDDFRCKNGACIHADLLCDRRNDCADFSDEELCNVNECLIPDI-CEHECEDKVVGYQCH 3033
Query: 964 CPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNL 1143
C GYK+ + C+DI+EC E C Q C N + C C + L H
Sbjct: 3034 CRPGYKVLPKSPHLCTDIDECDEQQPCSQTCINTYGSYKCLC-AKGYALVDHH------- 3085
Query: 1144 TMRGYCVSNNADKMKLFVARREGLYRLN-PKNPDEEVKKLASGEFIYGIDFDYGDRKIFW 1320
C + + M+L + R + +++ N + +L++ +D+D+ + ++W
Sbjct: 3086 ----TCKATSNVSMELIFSNRYYIRQVDMTGNGSILINELSNA---VALDYDWDSQCLYW 3138
Query: 1321 TDRLAH-SAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSS 1497
+D + E + + + LK+ P LAVDW+ LY + G I+VS
Sbjct: 3139 SDVTSTVGTIKRYCPKENKTQTLHQAMLKN---PDGLAVDWVAKNLYWCDKGLDTIEVSQ 3195
Query: 1498 YDGERRTVLLADGLTLPLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQ 1668
DG+ R VL+ + L P IAL P + +F++ + + A MDG+N + ++
Sbjct: 3196 LDGKYRKVLINEYLREPRGIALHPYQQHIFWSDWGDSPHIGKAGMDGSNPKMIIRDGLGW 3255
Query: 1669 VSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRR-IVAQGMNV---VPHPFGLALFDQYL 1836
+ + + ++++W D + D + D GN R ++A+ +N + H F +A+++ ++
Sbjct: 3256 PNALTISFETQQLFWGDAREDTISVSDLDGNHTRLLLARSINPLLNLHHIFAIAVWEGHI 3315
Query: 1837 YWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENP 2016
YW+DW + F T + PM + +HP Q P NP
Sbjct: 3316 YWSDWETKSIEYCSIFNGQNCTTLITTIHR--PMDLRVFHPYRQQQPMSG--------NP 3365
Query: 2017 CTNADCEGMCILSKDNGGFGVGYKCACPIGQKLV-NGKRC 2133
C A+C +C+LS + YKC CP L +G+ C
Sbjct: 3366 CLAANCSTLCVLSPEE----PYYKCMCPTNFILADDGRTC 3401
Score = 197 bits (502), Expect = 5e-48
Identities = 145/563 (25%), Positives = 255/563 (44%), Gaps = 39/563 (6%)
Frame = +1
Query: 9298 CNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCA-NHKCVPNSWK 9474
C F C++ CI W+CD DC D SDE + C C F+C + C+PN+W
Sbjct: 39 CPASYFTCNDGFCIPMRWKCDSKADCPDMSDEGSECA-PKCNEGQFRCGVSRHCIPNNWL 97
Query: 9475 CDGNDDCEDG--SDEKDCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRS 9648
CDG DC G SDE +CP KC + QC +G+C++ ++ CD +DC
Sbjct: 98 CDGEFDCGKGDISDELNCPNGD-----TPKCRAFEGQCRNGDCLELSRFCDGRWDC---- 148
Query: 9649 DESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNECYEGISG 9828
D L + + C C G +C C + + S+ C + +EC E
Sbjct: 149 DNDELQCDKQNAACAALNCSFNCKLTPQGARCYCPKDQVPESSNSTRCVDYDECSEP-GT 207
Query: 9829 CSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEP-EPFFLL-ANKHYIRKISIDGNKY 10002
C Q C + GSY+C CV GY + + C+ + P EP L+ ++ ++ + +G +
Sbjct: 208 CDQVCRNTPGSYECSCVSGY-AKTKGNRCRAINVPPTEPTTLIFLSRDGVQSVGTNGTEV 266
Query: 10003 ELAAQGFDNVVSLDID-LTEKKAYLIDQG--------------------------KLRLL 10101
DN D D + ++ L+ Q ++R
Sbjct: 267 IGPPGAKDNDKVTDKDGVGSEEELLLSQPLRFVHAFEVWHRNRTLCSLLFSWPELQMRCQ 326
Query: 10102 RVDLDEMDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTL 10281
RVD ++ L + + + + TE + +DW+ Y+++ + + +C +C+ +
Sbjct: 327 RVDDARVNWTL-PFSSFVSPQQFFTE-LRLDWLSGNWYLVSEDDGLVYLCTNAMTYCRVI 384
Query: 10282 IRDRIQQPKAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAI 10461
++ ++ ++ + P KG++F+T+W+ P + R LDGS L + P+++
Sbjct: 385 LQ-QVDPLSSLDLDPTKGFMFYTDWT--PSLSRSLLDGSNRT-----VLVTDQVYHPSSV 436
Query: 10462 AIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHIPAQRTSHV-----SSMVVFDDYLYWADW 10626
+D ++ ++W D + +E+ +D++G R + S V ++ VF++ +Y A W
Sbjct: 437 TLDLANELVYWIDIYKDEVNRVDYEGRNRWTLKRPLDSPVPLKTIHAVEVFENSIYLAAW 496
Query: 10627 NLREVLRCDKWTGKNETILKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCL--IG 10800
++ DK++ K IL+ V +LRI H +QP +PC DNN GC+ +C+
Sbjct: 497 MDTAIVALDKFSLKTH-ILQSNVSRGANLRIFHRQKQPEVAHPCRDNNAGCNQICVPQWT 555
Query: 10801 AGGNGYTCSCPDQFVLLSDQKTC 10869
G C C + L +Q TC
Sbjct: 556 KGFASAKCMCTAGY-KLHNQTTC 577
Score = 192 bits (489), Expect = 2e-46
Identities = 188/839 (22%), Positives = 330/839 (38%), Gaps = 62/839 (7%)
Frame = +1
Query: 3799 AESCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKCGNGR-C 3975
A C F C + G CIP WK SDE G +C+ QF+CG R C
Sbjct: 36 AGPCPASYFTC-NDGFCIPMRWKCDSKADCPDMSDE---GSECAPKCNEGQFRCGVSRHC 91
Query: 3976 ILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDGKTH 4155
I NNWLCDGE DCG G D S E C + KC C N C+ L + CDG+
Sbjct: 92 IPNNWLCDGEFDCGKG-DISDELNCPNG-DTPKCRAFEGQCRNGD--CLELSRFCDGRWD 147
Query: 4156 CPGGTDEGGRCARDLCSADRAGCSFKCHNSPNGPICSCPFGE--QLVNKTKCEPENECLD 4329
C ++ +C + + CSF C +P G C CP + + N T+C +EC +
Sbjct: 148 CD---NDELQCDKQNAACAALNCSFNCKLTPQGARCYCPKDQVPESSNSTRCVDYDECSE 204
Query: 4330 SSSCSQRCKDEKHGFTCSCDEGYELDVDK--RTCKVADNVKDTRIYVS------------ 4467
+C Q C++ + CSC GY R V T I++S
Sbjct: 205 PGTCDQVCRNTPGSYECSCVSGYAKTKGNRCRAINVPPTEPTTLIFLSRDGVQSVGTNGT 264
Query: 4468 ---------NRNRIYYSD-----------------HKLDNWHTFGAIVENAIALAWDSLT 4569
+ +++ D H + WH + ++ +W L
Sbjct: 265 EVIGPPGAKDNDKVTDKDGVGSEEELLLSQPLRFVHAFEVWHRNRTLC--SLLFSWPEL- 321
Query: 4570 DRIYWSDIREKKILSANRNGT-NATVFIADGLDITEGIALDWVGRNLYWVDSSLNTIEVA 4746
+R +++ A N T + F++ TE + LDW+ N Y V + +
Sbjct: 322 ------QMRCQRVDDARVNWTLPFSSFVSPQQFFTE-LRLDWLSGNWYLVSEDDGLVYLC 374
Query: 4747 NLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQNPCIERASMDGTDRQIIVKTKI 4926
R +L Q V + +DP KG MF+TDW P + R+ +DG++R ++V ++
Sbjct: 375 TNAMTYCRVIL--QQVDPLSSLDLDPTKGFMFYTDW--TPSLSRSLLDGSNRTVLVTDQV 430
Query: 4927 YWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGR---TQVLASSKFVQHPHALAIFEDM 5097
Y P+++ LD + VY+ D D ++ V+Y+G R + L S ++ HA+ +FE+
Sbjct: 431 YHPSSVTLDLANELVYWIDIYKDEVNRVDYEGRNRWTLKRPLDSPVPLKTIHAVEVFENS 490
Query: 5098 MYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTN--PCS 5271
+Y + + K+ + S+ + H QP + +PC N C+
Sbjct: 491 IYLAAWMDTAIVALDKF--SLKTHILQSNVSRGANLRIFHRQKQPEVA-HPCRDNNAGCN 547
Query: 5272 HLCLLNNKNTFT---CKCPMGEKLDASGKKCIDDAKPFLVIIQK--TNVFGIEMNSASEK 5436
+C+ F C C G KL + FLV K + GI +++ +
Sbjct: 548 QICVPQWTKGFASAKCMCTAGYKLHNQTTCLLSALDKFLVYSDKHLARISGIPLDTEQVQ 607
Query: 5437 ETPVLAG----MVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTVN 5604
+ + MVP+ + + + +F + + A +I ++N
Sbjct: 608 QLEQIGEQPDVMVPVYNVSKTLAIDVNVRGKAVFYVVADSGASPFGNGEPSCSIRSQSLN 667
Query: 5605 GGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVILSNDQSXX 5784
G+ +++ + + + + FDW +L + + +R K V+ N
Sbjct: 668 -GSVSRLLAQGL-KRVHAVAFDWINDHLYWTSHKKMQVAPLRNLSK----VLTFNTDCDA 721
Query: 5785 XXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIA----SNDLAELDHIA 5952
G ++W + +A + + +DG++ ++A S + +
Sbjct: 722 MSLELDPTT-----GLLYWSQWESQSCEAGIYSSWMDGTHKELLAKGTSSMPMQWPRSLD 776
Query: 5953 IDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAFDSI 6129
+D +Y+ + + I + DG R + P + +++AD+ +I
Sbjct: 777 VDRRTKELYWCDIRLSTIELMRLDGTGREVLFKSDQFHPYSIVQNNGLIYWADNKNSTI 835
Score = 153 bits (386), Expect = 1e-34
Identities = 93/258 (36%), Positives = 121/258 (46%), Gaps = 4/258 (1%)
Frame = +1
Query: 265 HPGCKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCAD 444
HP + + D + S CI CD++ DC D SDEK C + + C +
Sbjct: 2664 HPSNNNTKEMPDMFRCGSGECIPRKFLCDSLKDCRDFSDEKMCAPIPCEKNDMTFVHCGN 2723
Query: 445 GRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDC 624
C +CDG DC D +DE D + +C QFRCA CI SW CDG KDC
Sbjct: 2724 STICIMPRWRCDGDPDCPDGTDELDCANHTSLSCDPGQFRCA-SGNCIAGSWHCDGEKDC 2782
Query: 625 ADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDE-DECGEYRCPPGKW 801
DGSDE + C +C N+F C +K C P ++CD DC D SDE +C C P +
Sbjct: 2783 PDGSDEIN-CR-TECRHNQFAC-DKTCIPASWQCDGKSDCEDGSDEGPQCPNRPCRPHLF 2839
Query: 802 NCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLGCQA---GCHPSPHGGECTCPS 972
C +G CI Q +CDG KDC G ++ S++ P G A C P H C S
Sbjct: 2840 QCKSSGRCIPQKWVCDGEKDCPSGLGDEG-SEDEGPQCGGVAHIPDCPPPAH----LCTS 2894
Query: 973 GYKLDDRFHRTCSDINEC 1026
G +D H C +C
Sbjct: 2895 GLCIDS--HYVCDGDEDC 2910
Score = 148 bits (374), Expect = 3e-33
Identities = 77/209 (36%), Positives = 104/209 (48%), Gaps = 2/209 (0%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQ 453
C + +C S C+ +RCD + DC G DE C T ++ F C + R
Sbjct: 3485 CFDNHMKCGATANSSAFCVDNVKRCDGVKDCPGGEDESAC---TPLVCKKDQFQCGNNR- 3540
Query: 454 CFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADG 633
C CDG DC D SDE + ++ +C F+C D +CI +W CD DC +G
Sbjct: 3541 CMPFVWVCDGDIDCPDKSDEANC---DNVSCGPNDFQC-DSGRCIPLAWRCDDDHDCPNG 3596
Query: 634 SDEPDTCEFKKCTANE--FQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNC 807
DEP +C K T + F+C N +C P ++RCDY +DCGD SDE C C ++ C
Sbjct: 3597 EDEPASCFSSKATCDPTYFKCNNSKCIPGRWRCDYENDCGDGSDELNCQMRNCSESEFRC 3656
Query: 808 PGTGHCIDQLKLCDGSKDCADGADEQQCS 894
GTG CI CDG C D +DE C+
Sbjct: 3657 -GTGKCIKHNYRCDGEIHCDDNSDEINCN 3684
Score = 147 bits (372), Expect = 6e-33
Identities = 147/582 (25%), Positives = 238/582 (40%), Gaps = 35/582 (6%)
Frame = +1
Query: 11875 CSPFEFECANSVCIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNIL 12054
C F C + CIP ++ SDE SEC + +C+ +FRC SR C+
Sbjct: 39 CPASYFTCNDGFCIPMRWKCDSKADCPDMSDE-GSEC-APKCNEG-QFRCGVSRHCIPNN 95
Query: 12055 QLCNGFNDCGPNDFSDEHLSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDAS 12234
LC+G DCG D SDE + + C + + +C NG C+ + CD + DC +
Sbjct: 96 WLCDGEFDCGKGDISDE---LNCPNGDTPKCRAFEGQCRNGDCLELSRFCDGRWDCDN-- 150
Query: 12235 DEIGCSKHGGKTSCEAFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAG 12414
DE+ C K +C A C C G C+C P+ + C+D DEC+
Sbjct: 151 DELQCDKQNA--ACAALN----CSFNCKLTPQGARCYCPKDQVPESSNSTRCVDYDECSE 204
Query: 12415 NNTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLH 12594
TC Q+C NT GSY C C Y G CR A NV +L+ LS
Sbjct: 205 PGTCDQVCRNTPGSYECSCVSGY------AKTKGNRCR----AINVPPTEPTTLIFLSRD 254
Query: 12595 G------SGTNRHXXXXXXXXXXXXXXXXXXPRKELM----------YWIDGSERTIYRS 12726
G +GT +EL+ + + RT+
Sbjct: 255 GVQSVGTNGTEVIGPPGAKDNDKVTDKDGVGSEEELLLSQPLRFVHAFEVWHRNRTLCSL 314
Query: 12727 AIANGNQSHEGQKLD----------VDFAAMGVVPTAIAVDYTTGNLFIAAVSENIENGL 12876
+ Q++D F + T + +D+ +GN ++ VSE ++GL
Sbjct: 315 LFSWPELQMRCQRVDDARVNWTLPFSSFVSPQQFFTELRLDWLSGNWYL--VSE--DDGL 370
Query: 12877 VTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGL 13056
V ++C Y +++ + ++L P+ G + Y+D
Sbjct: 371 V-------------------YLCTNAMTYC-RVILQQVDPLSSLDLDPTKGFMFYTD--W 408
Query: 13057 HAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTT 13236
+ + +DG++R ++V D V+ P+S+ +D +YW+D V+ V+ +G R T
Sbjct: 409 TPSLSRSLLDGSNRTVLVTDQVYHPSSVTLDLA-NELVYWIDIYKDEVNRVDYEGRNRWT 467
Query: 13237 VVH--DRHIP----YAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRV 13398
+ D +P +AV+VFEN IY + + DKF + +L S++ G +R+
Sbjct: 468 LKRPLDSPVPLKTIHAVEVFENSIYLAAWMDTAIVALDKFSL-KTHILQSNVSRGANLRI 526
Query: 13399 SQKYAKDTQRTVSGCERAQCSHLCVSLPSTGFA---CLCPDG 13515
+ + A C+ +CV + GFA C+C G
Sbjct: 527 FHRQKQPEVAHPCRDNNAGCNQICVPQWTKGFASAKCMCTAG 568
Score = 129 bits (323), Expect = 3e-27
Identities = 98/294 (33%), Positives = 131/294 (44%), Gaps = 28/294 (9%)
Frame = +1
Query: 304 YTWHSVSCIAEYQRCDNITDCADGSDE-------KDCPASTVDCSSQNVFMCADGRQCFD 462
Y HS CI CDN+T CADGSDE + CP + FMC + R C
Sbjct: 2582 YNCHSGECIPLELTCDNVTHCADGSDEFRSYCIFRQCP--------ETHFMCQNHR-CIP 2632
Query: 463 VSKKCDGKYDCRDLSDEKD---SC---------SRNHTACFQYQFRCADKTQCIQKSWVC 606
KCDG+ C D SDE C S N+T FRC +CI + ++C
Sbjct: 2633 KEHKCDGEQQCGDGSDETPLLCKCQSEDIDMHPSNNNTKEMPDMFRCG-SGECIPRKFLC 2691
Query: 607 DGSKDCADGSDEPDTCEFKKCTANEF---QCKNKR-CQPRKFRCDYYDDCGDNSDEDECG 774
D KDC D SDE C C N+ C N C ++RCD DC D +DE +C
Sbjct: 2692 DSLKDCRDFSDE-KMCAPIPCEKNDMTFVHCGNSTICIMPRWRCDGDPDCPDGTDELDCA 2750
Query: 775 EY---RCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSP 945
+ C PG++ C +G+CI CDG KDC DG+DE + C+ C +
Sbjct: 2751 NHTSLSCDPGQFRC-ASGNCIAGSWHCDGEKDCPDGSDE----------INCRTECRHNQ 2799
Query: 946 HGGECTC-PSGYKLDDRFHRTCSDINECAEFGYC-DQLCANHRPGFTCSCLGDC 1101
+ TC P+ ++ D + C D ++ E C ++ C H F C G C
Sbjct: 2800 FACDKTCIPASWQCDGK--SDCEDGSD--EGPQCPNRPCRPHL--FQCKSSGRC 2847
Score = 124 bits (312), Expect = 5e-26
Identities = 100/346 (28%), Positives = 133/346 (37%), Gaps = 68/346 (19%)
Frame = +1
Query: 274 CKSDQWQC-DTYTWHSVSCIAEYQRCDNITDCADGSDEKD------CPASTVDCSSQ--- 423
C + ++C +TY CI Y RCD DC DGSDE + C C+++
Sbjct: 3405 CTAAHFECVNTY-----KCIPFYWRCDTQDDCGDGSDEPETCPPFHCEPGQYQCANKKCT 3459
Query: 424 -------NVFMCADGRQ-------------------------CFDVSKKCDGKYDCRDLS 507
+ C DG C D K+CDG DC
Sbjct: 3460 HPSNLCDGINQCGDGSDELNCDKFTCFDNHMKCGATANSSAFCVDNVKRCDGVKDCPGGE 3519
Query: 508 DEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQ 687
DE +C+ C + QF+C + +C+ WVCDG DC D SDE + C+ C N+FQ
Sbjct: 3520 DE-SACT--PLVCKKDQFQCGN-NRCMPFVWVCDGDIDCPDKSDEAN-CDNVSCGPNDFQ 3574
Query: 688 CKNKRCQPRKFRCDYYDDCGDNSDEDE---CGEYRCPPGKWNCPGTGHCIDQLKLCDGSK 858
C + RC P +RCD DC + DE + C P + C CI CD
Sbjct: 3575 CDSGRCIPLAWRCDDDHDCPNGEDEPASCFSSKATCDPTYFKC-NNSKCIPGRWRCDYEN 3633
Query: 859 DCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSD----IN-- 1020
DC DG+DE C C + G G+C Y+ D H C D IN
Sbjct: 3634 DCGDGSDELNCQMRNCSESEFRCGT------GKC-IKHNYRCDGEIH--CDDNSDEINCN 3684
Query: 1021 --------ECAEFGYC---------DQLCANHRPGFTCSCLGDCFT 1107
+CA F C D C + C+C D F+
Sbjct: 3685 ITCKENQFKCAAFNTCINKQYKCDGDDDCPDGSDEVNCTCHSDHFS 3730
Score = 119 bits (299), Expect = 2e-24
Identities = 77/240 (32%), Positives = 97/240 (40%), Gaps = 6/240 (2%)
Frame = +1
Query: 391 CPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCA 570
CPAS F C DG C + KCD K DC D+SDE C+ C + QFRC
Sbjct: 39 CPAS--------YFTCNDGF-CIPMRWKCDSKADCPDMSDEGSECAPK---CNEGQFRCG 86
Query: 571 DKTQCIQKSWVCDGSKDCADG--SDEPD--TCEFKKCTANEFQCKNKRCQPRKFRCDYYD 738
CI +W+CDG DC G SDE + + KC A E QC+N C CD
Sbjct: 87 VSRHCIPNNWLCDGEFDCGKGDISDELNCPNGDTPKCRAFEGQCRNGDCLELSRFCD--- 143
Query: 739 DCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQN--LCPS 912
G+W+C DE QC + C +
Sbjct: 144 ------------------GRWDCDN---------------------DELQCDKQNAACAA 164
Query: 913 LGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCL 1092
L C C +P G C CP + C D +EC+E G CDQ+C N + CSC+
Sbjct: 165 LNCSFNCKLTPQGARCYCPKDQVPESSNSTRCVDYDECSEPGTCDQVCRNTPGSYECSCV 224
Score = 119 bits (298), Expect = 2e-24
Identities = 62/165 (37%), Positives = 80/165 (47%), Gaps = 9/165 (5%)
Frame = +1
Query: 502 LSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANE 681
L+D+ +C N TA F C + +CI W CD DC DGSDEP+TC C +
Sbjct: 3394 LADDGRTCRANCTAA---HFECVNTYKCIPFYWRCDTQDDCGDGSDEPETCPPFHCEPGQ 3450
Query: 682 FQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGH----CIDQLKLCD 849
+QC NK+C CD + CGD SDE C ++ C C T + C+D +K CD
Sbjct: 3451 YQCANKKCTHPSNLCDGINQCGDGSDELNCDKFTCFDNHMKCGATANSSAFCVDNVKRCD 3510
Query: 850 GSKDCADGADEQQCSQNLCPSLGCQAG---CHPSPH--GGECTCP 969
G KDC G DE C+ +C Q G C P G+ CP
Sbjct: 3511 GVKDCPGGEDESACTPLVCKKDQFQCGNNRCMPFVWVCDGDIDCP 3555
Score = 103 bits (256), Expect = 2e-19
Identities = 70/223 (31%), Positives = 101/223 (44%), Gaps = 10/223 (4%)
Frame = +1
Query: 337 YQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEK 516
Y +C T+ D + C A+ C++ + F C + +C +CD + DC D SDE
Sbjct: 3383 YYKCMCPTNFILADDGRTCRAN---CTAAH-FECVNTYKCIPFYWRCDTQDDCGDGSDEP 3438
Query: 517 DSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQC-- 690
++C H C Q++CA+K +C S +CDG C DGSDE + C+ C N +C
Sbjct: 3439 ETCPPFH--CEPGQYQCANK-KCTHPSNLCDGINQCGDGSDELN-CDKFTCFDNHMKCGA 3494
Query: 691 ---KNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKD 861
+ C RCD DC DE C C ++ C G C+ + +CDG D
Sbjct: 3495 TANSSAFCVDNVKRCDGVKDCPGGEDESACTPLVCKKDQFQC-GNNRCMPFVWVCDGDID 3553
Query: 862 CADGADEQQCSQNLC--PSLGCQAG-CHPSPH--GGECTCPSG 975
C D +DE C C C +G C P + CP+G
Sbjct: 3554 CPDKSDEANCDNVSCGPNDFQCDSGRCIPLAWRCDDDHDCPNG 3596
Score = 97.1 bits (240), Expect = 1e-17
Identities = 61/192 (31%), Positives = 85/192 (43%), Gaps = 16/192 (8%)
Frame = +1
Query: 11377 CKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRW 11556
C + C+ + CIP C+ + DC D SDE + P C++ G+FRC S CIP W
Sbjct: 39 CPASYFTCNDGF-CIPMRWKCDSKADCPDMSDEGSECAPKCNE-GQFRCGVSRHCIPNNW 96
Query: 11557 MCDTENDC--GDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDES 11730
+CD E DC GD SDEL+ G T + C E +C +G C+ S+ CDG C + DE
Sbjct: 97 LCDGEFDCGKGDISDELNCPNGDTPK-CRAFEGQCRNGDCLELSRFCDGRWDCDN--DEL 153
Query: 11731 QCTLRRCLPGHRQC--------DDGTC------IAEHKWCDRKKDCPNAADELHCEDVSR 11868
QC + C C + E R D ++ C+ V R
Sbjct: 154 QCDKQNAACAALNCSFNCKLTPQGARCYCPKDQVPESSNSTRCVDYDECSEPGTCDQVCR 213
Query: 11869 RTCSPFEFECAN 11904
T +E C +
Sbjct: 214 NTPGSYECSCVS 225
Score = 94.4 bits (233), Expect = 7e-17
Identities = 71/231 (30%), Positives = 97/231 (41%), Gaps = 22/231 (9%)
Frame = +1
Query: 8380 PPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKC 8559
P F C DG CI + CDSK DC D SDE + C + + +R CI + C
Sbjct: 40 PASYFTCNDGFCIPMRWKCDSKADCPDMSDEG-SECAPKCNEGQFRCGVSRHCIPNNWLC 98
Query: 8560 NHIDDCGDG--SDELDCPS--AVACAEGTFPCSNGHCINQTKVCDGHNDC-HDEQVSDES 8724
+ DCG G SDEL+CP+ C C NG C+ ++ CDG DC +DE D+
Sbjct: 99 DGEFDCGKGDISDELNCPNGDTPKCRAFEGQCRNGDCLELSRFCDGRWDCDNDELQCDKQ 158
Query: 8725 LATCPGL--PIDCR----GVKVRCPNTNIC-IQPADLCDGYDDCGDKADENQLFCMNQ-- 8877
A C L +C+ G + CP + + C YD+C + +Q+ C N
Sbjct: 159 NAACAALNCSFNCKLTPQGARCYCPKDQVPESSNSTRCVDYDECSEPGTCDQV-CRNTPG 217
Query: 8878 ----QCAQHYVRCPSGRC----IPETWQCDGDNDCSDGWDETHTNCTDTAG 9006
C Y + RC +P T DG TN T+ G
Sbjct: 218 SYECSCVSGYAKTKGNRCRAINVPPTEPTTLIFLSRDGVQSVGTNGTEVIG 268
Score = 92.0 bits (227), Expect = 4e-16
Identities = 93/398 (23%), Positives = 170/398 (42%), Gaps = 41/398 (10%)
Frame = +1
Query: 7231 CTQLCFATPGTQTPTCSCARGVLKGRTCE-------EPDTYIMFS--------------- 7344
C Q+C TPG+ +C KG C EP T I S
Sbjct: 208 CDQVCRNTPGSYECSCVSGYAKTKGNRCRAINVPPTEPTTLIFLSRDGVQSVGTNGTEVI 267
Query: 7345 ------DGDKIID---VAIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVG 7497
D DK+ D V E ++ S+PL+ + F+V R + ++ S
Sbjct: 268 GPPGAKDNDKVTDKDGVGSEEELLLSQPLRF-------VHAFEVWHRNRTLCSLLFSWPE 320
Query: 7498 VNISWFSMNNAE-NPRLVFGASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVMAIDT 7674
+ + +++A N L F + P + ++++LDWL+ Y + G V
Sbjct: 321 LQMRCQRVDDARVNWTLPFSSFVSPQ----QFFTELRLDWLSGNWYLVSEDDGLVYLCTN 376
Query: 7675 AGEHLSTIASG-DWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVS 7851
A + I D +L +DP G +F++D + P + RS L G +R V+V+
Sbjct: 377 AMTYCRVILQQVDPLSSLDLDPTKGFMFYTD---------WTPSLSRSLLDGSNRTVLVT 427
Query: 7852 ESISLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNR----KVIASGYRAKSL---DIW 8010
+ + P+++ +D N+ +YW D+ + + DY+G+NR + + S K++ +++
Sbjct: 428 DQVYHPSSVTLDLANELVYWIDIYKDEVNRVDYEGRNRWTLKRPLDSPVPLKTIHAVEVF 487
Query: 8011 DRWLYMSDPLSNGVFRIDKESGSGLENVVSDRRIPGA-LRVFASESDVRTRNQVCNALTS 8187
+ +Y++ + + +DK S +++ GA LR+F + +
Sbjct: 488 ENSIYLAAWMDTAIVALDKFSLK--THILQSNVSRGANLRIFHRQKQPEVAHP------- 538
Query: 8188 QLCKTDNGGCDQLCTVVADDIGLAASKVQCSCNDTYEL 8301
C+ +N GC+Q+C V G A++K C C Y+L
Sbjct: 539 --CRDNNAGCNQIC-VPQWTKGFASAK--CMCTAGYKL 571
Score = 91.7 bits (226), Expect = 5e-16
Identities = 59/191 (30%), Positives = 85/191 (43%), Gaps = 29/191 (15%)
Frame = +1
Query: 421 QNVFMCADGRQCFDVSKKCD--------GKYDCRDLS-----DEKDSCSRNHTACFQYQF 561
QN + D QC ++ +C+ G+ C D + + +T+C Q+
Sbjct: 2523 QNTSINCDANQCKILNGQCEDVCILNKSGQATCHCTQGVLAPDGRRCIAPVNTSCGLSQY 2582
Query: 562 RCADKTQCIQKSWVCDGSKDCADGSDE-PDTCEFKKCTANEFQCKNKRCQPRKFRCDYYD 738
C +CI CD CADGSDE C F++C F C+N RC P++ +CD
Sbjct: 2583 NC-HSGECIPLELTCDNVTHCADGSDEFRSYCIFRQCPETHFMCQNHRCIPKEHKCDGEQ 2641
Query: 739 DCGDNSDED----EC-----------GEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADG 873
CGD SDE +C + P + C G+G CI + LCD KDC D
Sbjct: 2642 QCGDGSDETPLLCKCQSEDIDMHPSNNNTKEMPDMFRC-GSGECIPRKFLCDSLKDCRDF 2700
Query: 874 ADEQQCSQNLC 906
+DE+ C+ C
Sbjct: 2701 SDEKMCAPIPC 2711
Score = 88.2 bits (217), Expect = 5e-15
Identities = 135/667 (20%), Positives = 247/667 (36%), Gaps = 55/667 (8%)
Frame = +1
Query: 7231 CTQLCFATPGTQTPTCSCARGVLKGRTCEEPDTYIMFSDGDKIIDVAIEPDVKASRPLKD 7410
C+Q+C C CA G KG E + + S D+I+ +A E + + P K
Sbjct: 3851 CSQICIEKKAGHY-NCKCADGYHKG---PEKNATCLASGPDQILLLASEQEFRFILPAKQ 3906
Query: 7411 PFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAENPRLVFGAS---------- 7560
+ F D V+ ++ P + W ++ + +
Sbjct: 3907 EGTTVVGF--FQTDSLKIDVFDILIRPKDTLLFWIDSHHGKVHTMKIATPHVEGTGVRVR 3964
Query: 7561 ---KQPHAKEIRHISDMK---LDWLTQKIYFTTGRGGKVMAIDTAG-EHLSTIASGDWTY 7719
K+ A I + D K +DW++Q++Y R +++A D G +++S +++G
Sbjct: 3965 RDLKELTAFNIPELDDPKSLAVDWISQRVYIIDSRHNQILATDIEGKKYISLVSTGMNPT 4024
Query: 7720 ALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVDFRNQ 7899
+ ++P S ++ WS E I ++L G ++K +V + P ++++D+
Sbjct: 4025 DIVLEPESRIMIWS---------TLENGILVASLDGSNKKSLVERDVGWPISLSMDYPTG 4075
Query: 7900 KIYWADVNRLNIEVADYDGQNRKVIAS-GYRAK--SLDIWDRWLYMS--DPLSNGVFRID 8064
++YWAD + IE +G++R V+ G R K +D+++ +LY+ D + +
Sbjct: 4076 RLYWADYRKGTIETCRLNGKDRNVVRRFGNREKPQKIDVFEDYLYIKLYDQSIIKMNKFG 4135
Query: 8065 KESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLCTVVAD 8244
++G+ L I G L ++ + N CK+ C +++
Sbjct: 4136 NDNGTYLLKGYRSSDI-GILH------PMKQNRNISNPCAKDPCKSSRALC-----ILSS 4183
Query: 8245 DIGLAASKVQCSCNDTYEL----VQEPGKDYPTQCVLRGSNSEPAKECLPPYNFQCGDGS 8412
+ + S C C + Y + V + D P C L QC G+
Sbjct: 4184 ESSVGYS---CKCAEGYVMTDDGVCKAHADIPDYCPL-----------------QCNLGT 4223
Query: 8413 CILLGATCDSKPDCADASDENPNYCNTRSCP---EDYNLCTNRRCIDSAK-----KCNHI 8568
C ++ D P C C C ++Y +C+ + ++ KC
Sbjct: 4224 CKIV----DHVPKCICQPQFEGELCEHYRCSGYCQNYGVCSVAPALPGSQEPPPLKCT-- 4277
Query: 8569 DDCGDGSDELDCPSAVACAEGTFPCSNGH--CINQTKVCDGHNDCHDEQVSDESLATCPG 8742
C G C +++ + C NG I++T +G + + E C
Sbjct: 4278 --CTAGWSGARCETSMPACQSR--CHNGGSCLISET---EGMKCSCPKMFTGEQCEHCRN 4330
Query: 8743 LPIDCRGVKVRCPNTNICIQPADLCDGY-------DDCGDKADENQLFCMNQQCAQHYVR 8901
L + G+ C T + DG+ D+C D +N C+ Q +
Sbjct: 4331 LTCENGGI---CRETLTGTPQCECPDGFTGKRCEIDECADFC-KNGGSCVISTKGQRQCK 4386
Query: 8902 CPSG----RCIPETWQ--CDGDNDCSDGWDETHTNCTDTAGKKICVGDYL------FQCD 9045
CPSG C + + C CS+ C + C D CD
Sbjct: 4387 CPSGYFGEHCESNSCRDFCRNGGTCSERGGRLSCTCPPRYIGESCESDLCKTSSPPHFCD 4446
Query: 9046 NLKCISR 9066
N K +R
Sbjct: 4447 NTKVPTR 4453
Score = 80.5 bits (197), Expect = 1e-12
Identities = 56/218 (25%), Positives = 85/218 (38%), Gaps = 33/218 (15%)
Frame = +1
Query: 559 FRCADKTQCIQKSWVCDGSKDCADGSDEPDT----CEFKKCT-ANEFQCKNKRCQPRKFR 723
+ C QC+ +CDG +DC DG DE C C + F C N RC R
Sbjct: 931 YMCRSTRQCLDTKDMCDGFEDCEDGIDESSDPKGPCNVNTCDKTHNFVC-NGRCYQRSLL 989
Query: 724 CDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNL 903
C C D +D+ C + C ++ C +G CI + DG DC D + S+ +
Sbjct: 990 CSTIPYCSDGTDQANCHQNTCNSNEFTCHKSGRCIQLTWVNDGVVDCGPDDDSDETSETI 1049
Query: 904 ----CPSLGCQAG--------CHPSPHGG----ECTCPSGYKLDDRFHR---------TC 1008
CP C G C + G E C + +++ R C
Sbjct: 1050 FASKCPEFDCNNGRCRQFADVCDGIDNCGNNADEMECEQECEHGEKYCRPIGCYGEMHMC 1109
Query: 1009 SDINECAEF---GYCDQLCANHRPGFTCSCLGDCFTLQ 1113
I++C +F C+Q +++ P LG+C L+
Sbjct: 1110 DGIHDCLDFSDEANCNQTKSDNHPVTEWKELGECAPLE 1147
Score = 77.4 bits (189), Expect = 9e-12
Identities = 60/188 (31%), Positives = 83/188 (43%), Gaps = 15/188 (7%)
Frame = +1
Query: 8500 CPEDYNLCTNRRCIDSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCS-NGHCINQTKV 8676
CP Y C + CI KC+ DC D SDE A C EG F C + HCI +
Sbjct: 39 CPASYFTCNDGFCIPMRWKCDSKADCPDMSDE-GSECAPKCNEGQFRCGVSRHCIPNNWL 97
Query: 8677 CDGHNDCHDEQVSDESLATCP-GLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGD---K 8844
CDG DC +SDE CP G CR + +C N + C++ + CDG DC + +
Sbjct: 98 CDGEFDCGKGDISDE--LNCPNGDTPKCRAFEGQCRNGD-CLELSRFCDGRWDCDNDELQ 154
Query: 8845 ADENQLFCMNQQCAQHYVRCPSG-RC------IPE---TWQCDGDNDCSDGWDETHTNCT 8994
D+ C C+ + P G RC +PE + +C ++CS+ C
Sbjct: 155 CDKQNAACAALNCSFNCKLTPQGARCYCPKDQVPESSNSTRCVDYDECSEP-GTCDQVCR 213
Query: 8995 DTAGKKIC 9018
+T G C
Sbjct: 214 NTPGSYEC 221
Score = 69.7 bits (169), Expect = 2e-09
Identities = 58/210 (27%), Positives = 77/210 (36%), Gaps = 7/210 (3%)
Frame = +1
Query: 11257 CTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXETPECAQIECKKGWTRCSSSYRCIPNWAF 11436
C A F CN+ CI W+ E ECA +C +G RC S CIPN
Sbjct: 39 CPASYFTCNDGFCIPMRWKCDSKADCPDMSDEGSECAP-KCNEGQFRCGVSRHCIPNNWL 97
Query: 11437 CNGQDDCRDNSDEDKQRCPTCDD----VGEFRCATSGKCIPRRWMCDTENDCGDNSDELD 11604
C+G+ DC D+ CP D E +C +G C+ CD DC ++DEL
Sbjct: 98 CDGEFDCGKGDISDELNCPNGDTPKCRAFEGQC-RNGDCLELSRFCDGRWDC--DNDELQ 154
Query: 11605 ASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQC---SDGLDESQCTLRRCLPGHRQCD 11775
C + C C K+ +C D + ES RC+ +
Sbjct: 155 ---------CDKQNAACAALNCSFNCKLTPQGARCYCPKDQVPESS-NSTRCVDYDECSE 204
Query: 11776 DGTCIAEHKWCDRKKDCPNAADELHCEDVS 11865
GTC + C N C VS
Sbjct: 205 PGTC---------DQVCRNTPGSYECSCVS 225
Score = 68.9 bits (167), Expect = 3e-09
Identities = 59/228 (25%), Positives = 89/228 (38%), Gaps = 3/228 (1%)
Frame = +1
Query: 304 YTWHSVSCIAEYQRCDNITDCADGSDE-KDCPASTVDCSSQNVFMCADGRQCFDVSKKCD 480
+T + CI +CD+ DC D SDE +C ++ F C R C + CD
Sbjct: 44 FTCNDGFCIPMRWKCDSKADCPDMSDEGSECAPKC----NEGQFRCGVSRHCIPNNWLCD 99
Query: 481 GKYDC--RDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTC 654
G++DC D+SDE + + + C ++ +C + C++ S CDG DC +
Sbjct: 100 GEFDCGKGDISDELNCPNGDTPKCRAFEGQCRN-GDCLELSRFCDGRWDCDN-------- 150
Query: 655 EFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQ 834
+E QC + C + +C C CP DQ
Sbjct: 151 -------DELQCDKQNAACAALNCSF--NCKLTPQGARC---YCPK------------DQ 186
Query: 835 LKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGY 978
+ S C D +CS+ P C C +P EC+C SGY
Sbjct: 187 VPESSNSTRC---VDYDECSE---PGT-CDQVCRNTPGSYECSCVSGY 227
Score = 66.6 bits (161), Expect = 2e-08
Identities = 36/99 (36%), Positives = 46/99 (46%), Gaps = 3/99 (3%)
Frame = +1
Query: 11629 PCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQCD-DGTCIAEHKW 11805
PC S F CNDG CIP CD C D DE +C G +C CI +
Sbjct: 38 PCPASYFTCNDGFCIPMRWKCDSKADCPDMSDEGSECAPKCNEGQFRCGVSRHCIPNNWL 97
Query: 11806 CDRKKDC--PNAADELHCEDVSRRTCSPFEFECANSVCI 11916
CD + DC + +DEL+C + C FE +C N C+
Sbjct: 98 CDGEFDCGKGDISDELNCPNGDTPKCRAFEGQCRNGDCL 136
Score = 64.7 bits (156), Expect = 6e-08
Identities = 52/191 (27%), Positives = 74/191 (38%), Gaps = 13/191 (6%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAE 336
C + F CNDG CI W P C Q++C S CI
Sbjct: 39 CPASYFTCNDGFCIPMRWKCDSKADCPDMSDEGSECAPKCNEGQFRCGV----SRHCIPN 94
Query: 337 YQRCDNITDCADG--SDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSD 510
CD DC G SDE +CP C +G C ++S+ CDG++DC +
Sbjct: 95 NWLCDGEFDCGKGDISDELNCPNGDTPKCRAFEGQCRNG-DCLELSRFCDGRWDC---DN 150
Query: 511 EKDSCSRNHTAC--FQYQFRCADKTQCIQ----KSWVCDGSKD--CADGSD--EPDTC-E 657
++ C + + AC F C Q + K V + S C D + EP TC +
Sbjct: 151 DELQCDKQNAACAALNCSFNCKLTPQGARCYCPKDQVPESSNSTRCVDYDECSEPGTCDQ 210
Query: 658 FKKCTANEFQC 690
+ T ++C
Sbjct: 211 VCRNTPGSYEC 221
Score = 64.3 bits (155), Expect = 8e-08
Identities = 41/123 (33%), Positives = 54/123 (43%), Gaps = 3/123 (2%)
Frame = +1
Query: 8605 PSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPGLPIDCRGVKVRCPN 8784
P A C F C++G CI CD DC D +SDE P C + RC
Sbjct: 34 PIAGPCPASYFTCNDGFCIPMRWKCDSKADCPD--MSDEGSECAP----KCNEGQFRCGV 87
Query: 8785 TNICIQPADLCDGYDDCGDKADENQLFCMN---QQCAQHYVRCPSGRCIPETWQCDGDND 8955
+ CI LCDG DCG ++L C N +C +C +G C+ + CDG D
Sbjct: 88 SRHCIPNNWLCDGEFDCGKGDISDELNCPNGDTPKCRAFEGQCRNGDCLELSRFCDGRWD 147
Query: 8956 CSD 8964
C +
Sbjct: 148 CDN 150
Score = 62.4 bits (150), Expect = 3e-07
Identities = 33/102 (32%), Positives = 45/102 (43%)
Frame = +1
Query: 3172 STQFQCKNGRCIPKEWKCDGENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKKCIPA 3351
++ F C +G CIP WKCD + DC D SDE G +C +C E +C ++ CIP
Sbjct: 41 ASYFTCNDGFCIPMRWKCDSKADCPDMSDE----GSEC--APKCNEGQFRCGVSRHCIPN 94
Query: 3352 QXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNHRCI 3477
C +G P C A + QC N C+
Sbjct: 95 NWLCDGEFDCGKGDISDELNCPNGDTPKCRAFEGQCRNGDCL 136
Score = 62.0 bits (149), Expect = 4e-07
Identities = 37/103 (35%), Positives = 46/103 (43%), Gaps = 4/103 (3%)
Frame = +1
Query: 3436 CAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNATCAANQFSCANGR-CIPIYW 3612
C A F C++ CIP +WK E E C QF C R CIP W
Sbjct: 39 CPASYFTCNDGFCIPMRWKCDSKADCPDMSDEGSECAPK--CNEGQFRCGVSRHCIPNNW 96
Query: 3613 LCDGDNDCYDGTDEDKERCP---PVQCSALQFRCANGRQCVPL 3732
LCDG+ DC G D+ CP +C A + +C NG C+ L
Sbjct: 97 LCDGEFDCGKGDISDELNCPNGDTPKCRAFEGQCRNG-DCLEL 138
Score = 52.4 bits (124), Expect = 3e-04
Identities = 33/77 (42%), Positives = 37/77 (47%), Gaps = 3/77 (3%)
Frame = +1
Query: 10828 CPDQFVLLSDQKT-CEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDG--SDEPGESIC 10998
CPD +SD+ + C P C E QF CG CIP W CDGE DC G SDE
Sbjct: 64 CPD----MSDEGSECAPKCNEGQFRCGVS-RHCIPNNWLCDGEFDCGKGDISDELNCPNG 118
Query: 10999 GQRICPVGEFQCTNHNC 11049
C E QC N +C
Sbjct: 119 DTPKCRAFEGQCRNGDC 135
Score = 49.7 bits (117), Expect = 0.002
Identities = 32/103 (31%), Positives = 41/103 (39%), Gaps = 5/103 (4%)
Frame = +1
Query: 667 CTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDE-----CGEYRCPPGKWNCPGTGHCID 831
CT+ ++C K CD ++DC D DE C C N G C
Sbjct: 927 CTSGYMCRSTRQCLDTKDMCDGFEDCEDGIDESSDPKGPCNVNTCDK-THNFVCNGRCYQ 985
Query: 832 QLKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGEC 960
+ LC C+DG D+ C QN C S + CH S G C
Sbjct: 986 RSLLCSTIPYCSDGTDQANCHQNTCNS--NEFTCHKS---GRC 1023
Score = 43.1 bits (100), Expect = 0.20
Identities = 22/52 (42%), Positives = 27/52 (51%)
Frame = +1
Query: 10879 CTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQC 11034
C F C +D CIP W CD + DC D SDE E C + C G+F+C
Sbjct: 39 CPASYFTC--NDGFCIPMRWKCDSKADCPDMSDEGSE--CAPK-CNEGQFRC 85
Score = 41.6 bits (96), Expect = 0.57
Identities = 37/140 (26%), Positives = 49/140 (34%), Gaps = 12/140 (8%)
Frame = +1
Query: 9550 ASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCMDMK 9729
A C F C G CI CD DC D SDE S C P C +
Sbjct: 36 AGPCPASYFTCNDGFCIPMRWKCDSKADCPDMSDEGSEC---------APKCNEGQFRCG 86
Query: 9730 IGYKC-----------DCFEGFAIDISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCG- 9873
+ C DC +G DISD+ +C N G + KC G + G
Sbjct: 87 VSRHCIPNNWLCDGEFDCGKG---DISDELNCPN---------GDTPKCRAFEGQCRNGD 134
Query: 9874 CVDGYQLSSDDHSCKRTEME 9933
C++ + C E++
Sbjct: 135 CLELSRFCDGRWDCDNDELQ 154
Score = 38.9 bits (89), Expect = 3.7
Identities = 37/150 (24%), Positives = 50/150 (32%), Gaps = 28/150 (18%)
Frame = +1
Query: 12118 CSSFSE-YGDCS----------SDQFKC------ANGKCVNGTVACDRKDDCGDASDEIG 12246
CS + + YG CS KC + +C AC + C + +
Sbjct: 4249 CSGYCQNYGVCSVAPALPGSQEPPPLKCTCTAGWSGARCETSMPACQSR--CHNGGSCLI 4306
Query: 12247 CSKHGGKTSCEAFGNNGGCKH----------ICTDVRDGF-YCHCRDGFRPDPQSPKECI 12393
G K SC C+H IC + G C C DGF EC
Sbjct: 4307 SETEGMKCSCPKMFTGEQCEHCRNLTCENGGICRETLTGTPQCECPDGFTGKRCEIDECA 4366
Query: 12394 DIDECAGNNTCTQLCLNTKGSYLCRCHEDY 12483
D C +C ++TKG C+C Y
Sbjct: 4367 DF--CKNGGSCV---ISTKGQRQCKCPSGY 4391
>gi|16768036|gb|AAL28237.1| GH12891p [Drosophila melanogaster]
Length = 1952
Score = 1330 bits (3443), Expect = 0.0
Identities = 751/2021 (37%), Positives = 1053/2021 (51%), Gaps = 77/2021 (3%)
Frame = +1
Query: 8335 CVLRGSNSEPAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDY 8514
C R + E +K F C +G CI +CD DC D SDE+PNYC SC +
Sbjct: 2 CAPRNNTCEASK-------FYCKNGRCISRMWSCDGDDDCGDNSDEDPNYCAYHSCSPNE 54
Query: 8515 NLCTNRRCIDSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHND 8694
C N RCI + KC+H +DC DGSDEL C C +G F C+NG CI Q +VC+G ND
Sbjct: 55 FRCNNGRCIFKSWKCDHENDCKDGSDELGCVYP-PCVDGEFTCANGRCIPQAQVCNGVND 113
Query: 8695 CHDEQVSDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMN 8874
C D SDE+ CP + C ++C TNIC++P LCDG +DCGD +DE+ L C
Sbjct: 114 CKDNATSDETHERCP-MNTTCPANHLKCEKTNICVEPYWLCDGDNDCGDNSDEDPLHCGQ 172
Query: 8875 QQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLK 9054
+ C + RCP+ RCIP TW CDGD+DC DG DE C + C GD LF CDN
Sbjct: 173 RTCPTNSFRCPNHRCIPATWYCDGDDDCGDGADEPPDYCKSEG--RTCFGD-LFTCDNGN 229
Query: 9055 CISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQ-EFHCTSNAKLAQPKYECIPRAWLCD 9231
CI R +I +RH C +R C ++ EF C N + + +CIP+ W+CD
Sbjct: 230 CIPRIYICDGDNDCLDNSDEDNRHQCNDRKCDEETEFTCVENK--SWQRAQCIPKKWICD 287
Query: 9232 GDVTCAGGEDESTEL--CKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANC 9405
GD C G DE+T L C T++ C + F C N CI+ W CD DNDC DG+DE C
Sbjct: 288 GDPDCVDGADENTTLHNCATQQP-CGEDMFTCGNGRCINKGWICDHDNDCGDGTDEGKFC 346
Query: 9406 T--YSSCQPDFFQCANHKCVPNSWKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQ 9579
Y +C F C N KC+ N +CDG DDC D SDE C K + + C GQF
Sbjct: 347 NSKYKTCSAQEFTCQNFKCIRNQSRCDGEDDCGDHSDEVGCAKENIT------CPQGQFA 400
Query: 9580 CTSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEG 9759
CT+G+CID VC++ DC D SDE + C +DEC+ E C KC+D GY CDC EG
Sbjct: 401 CTNGQCIDYNLVCNKYPDCADESDEPAHCNVDECAKVEINQCGHKCVDTLTGYYCDCNEG 460
Query: 9760 FAIDISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGY-QLSSDDHSCKRTEMEP 9936
+ + ++D K+C +V+EC E CSQ C + G + C C + Y + +D+H+CKR + P
Sbjct: 461 YKL-LADGKACADVDECLEQPGACSQHCSNTPGGFYCKCDETYYERQNDEHTCKRKDKIP 519
Query: 9937 EPFFLLANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLD 10116
P+ + NK+Y+R +S+DG++Y L Q NVV+LD D+ E+ Y D + R
Sbjct: 520 -PWLIFTNKYYVRNMSVDGHQYNLMHQDLMNVVALDFDIREEYMYFCDVTAKTIFRAKYG 578
Query: 10117 EMDSPLS-SYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDR 10293
E D + E V+RH+ +G EGIA+DWVGRKLY L+R +++ V ELDG KTL R
Sbjct: 579 EADDEMPPEREAVIRHDSHGLEGIAIDWVGRKLYWLDRHSKNLDVSELDGSKRKTL-RSG 637
Query: 10294 IQQPKAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDY 10473
+ P+AIVVHPG GYL+FT W LQ YI ++ +DGS + + + WPNA++IDY
Sbjct: 638 VVDPRAIVVHPGIGYLYFTSWHLQAYIAKMGMDGSNFSRILNWN---DGIAWPNALSIDY 694
Query: 10474 FSDRLFWGDAHLNEIGFMDFDGNGRRHI-PAQRTSHVSSMVVFDDYLYWADWNLREVLRC 10650
F+DR++W DAHL+ I + D +G R + + HV ++ +FDDY+YW+DWNL+ ++R
Sbjct: 695 FTDRIYWADAHLDYIAYADLEGRHRHTVLSGSKVPHVFALSLFDDYIYWSDWNLKAIVRA 754
Query: 10651 DKWTGKNETILKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGA--------- 10803
+K+ G N T+L+ T P DL I HP+RQ Y NPCG NNGGCSHLCLI
Sbjct: 755 NKFHGANYTVLRNTTHRPYDLHINHPLRQLPYTNPCGTNNGGCSHLCLIAPPPESTYLNI 814
Query: 10804 ------GGNGYTCSCPDQFVLLSDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCR 10965
G + C+CP+QF L D KTC NCT Q CGG D KCIP W CDGE DC+
Sbjct: 815 EGYIEEGAPIFKCACPNQFYLARDMKTCVANCTAGQHLCGGRDEKCIPWFWKCDGEKDCK 874
Query: 10966 DGSDEPGESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXXEQNCDKACDPWMFK 11145
DGSDEP + C R C G FQC N NCT I EQNCD C FK
Sbjct: 875 DGSDEP--ATCAPRHCRAGTFQCKNTNCTPSATICDGVDDCGDRSDEQNCDLPCPLSDFK 932
Query: 11146 CAATGRCIPRRFTXXXXXXXXXRSDEADTLCMSAERNCTAE-EFRCNNNKCIAKAWRXXX 11322
C ++GRCI + SDE +C +R C + EF C N +CI + W
Sbjct: 933 CKSSGRCILDSWRCDGDADCKDGSDEDPAVCF--KRTCDPKTEFSCKNGRCIPQLWMCDF 990
Query: 11323 XXXXXXXXXETPE-CAQIECKKGWTRC--SSSYRCIPNWAFCNGQDDCRDNSDEDKQRCP 11493
E C Q C GW RC S+YRCIP W FC+G+DDCRDNSDE + CP
Sbjct: 991 DNDCGDDSDEPAYMCRQRNCTTGWQRCPGQSNYRCIPKWLFCDGKDDCRDNSDELPENCP 1050
Query: 11494 TCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCI 11673
C+ +F+C + +CIP++WMCD +DCGD SDE +A C G R CSESEFRC +GKCI
Sbjct: 1051 KCNPETDFKCGNN-RCIPKQWMCDFADDCGDASDENEAVCKGRYRECSESEFRCGNGKCI 1109
Query: 11674 PGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHC 11853
CD C D DE C +C G QC G CIA + CD +DC + +DE+ C
Sbjct: 1110 SSRWQCDHEDDCGDNSDEMHCEGYQCKNGTFQCASGHCIASYFRCDGDRDCRDMSDEVGC 1169
Query: 11854 ED--VSRRTCSPFEFECANSVCIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCA 12027
R C F+C N++C+ + SDE S C CD RF+C+
Sbjct: 1170 PPRFPGGRYCPESRFQCNNNLCVSLSDLCDGTDDCGDGSDEDPSVCSDFNCDTLRRFQCS 1229
Query: 12028 HSRLCLNILQLCNGFNDCGPNDFSDE-HLSMCSSFSEYGDCSSDQFKCANGKCVNGTVAC 12204
+ R C+ Q+C+G ++CG D SDE ++++C+S + D + Q++CAN C+ + C
Sbjct: 1230 NER-CVARYQICDGVDNCG--DGSDENNMTLCASKQKPCDLYT-QYQCANKHCIERSQVC 1285
Query: 12205 DRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKHICTDVRDGFY-CHCRDGFRPDPQSP 12381
D DDCGDASDE+GC H + EA N GGC+ C ++ DG Y C C G+ +
Sbjct: 1286 DFSDDCGDASDELGC--HHTSSCSEA--NRGGCQQHCHNLTDGGYICTCYPGYIIAADNK 1341
Query: 12382 KECIDIDEC-AGNNTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRA-KGDAANVM 12555
K+C D+DEC +TC+ C N G+Y C C E + + +G CRA K D +
Sbjct: 1342 KKCSDVDECLTRQHTCSHQCHNLNGTYSCSCREGFH---LTDGASGV-CRAEKEDVILLF 1397
Query: 12556 IGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERTIYRSAIA 12735
+ + + G ++ ++++++W D ++TI RS +
Sbjct: 1398 VNGQE------IRGLNWHKSEEFAVIAAEKRIEALDYDAQQQIVFWADSYDKTIKRSYMV 1451
Query: 12736 NG--NQSHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEP 12909
N ++ G D++ G PTA+AVD+ NL+ + T K R
Sbjct: 1452 NAIDGRAKIGFAQDLNMKG-GSKPTAVAVDWLASNLYWTEMDR-------TGSKPR---- 1499
Query: 12910 IDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDG 13089
G + V DGRY + IV L+ PT++ P GRI +SDAG KIE + MDG
Sbjct: 1500 ------GRVMVAKTDGRYRRSIVNAGLEVPTSIAVNPQLGRIYWSDAGSAPKIEVSWMDG 1553
Query: 13090 THRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHD---RHIP 13260
+ R+ ++ +++ P + ID + + IYWVD K ++++ DGS R +V RH P
Sbjct: 1554 SKRRPLITEMIRHPAGLTIDYSQDHIIYWVDTKLNAIESMRADGSRRKAIVRGDQLRH-P 1612
Query: 13261 YAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSG 13440
++D+FE++++W++R++ L QDKFGRG VL + + ++V +T +
Sbjct: 1613 VSLDLFESNMFWMTRDTGELVRQDKFGRGVQVVLHRYIVNPSGLKVYHDKRYNTS-LPNP 1671
Query: 13441 CERAQCSHLCVSLPSTGFACLCPDGIVP--------QLDGSCATQHVEALTMPKQCKCTN 13596
C+ + CSHLC+ +P G C CPD P ++ + A +H P+ C C N
Sbjct: 1672 CDNSTCSHLCLLVPG-GHRCACPDASGPPPSHRSTAEVICNAAAEHPR--PAPRICPCQN 1728
Query: 13597 GGKCRLDGS----CECTSDFEGDQCEKESSVSRKIIGTLSENFITVXXXXXXXXXXXXXX 13764
GG C+ D CEC + F G+ CE + +G V
Sbjct: 1729 GGLCKEDAQGELLCECRTQFVGEHCETST------MGAFGHGDANVTAVVVPIMVILLVM 1782
Query: 13765 XXXXXNLYKRRQLLFKK-----NEAADGSVSF-HGNVISFSNPVLENKQD------APGS 13908
Y R+ F K + SV+F HG+ + F+ AP
Sbjct: 1783 MAAAGAWYVIRKRPFGKLARMPAMTSSQSVTFRHGSNVEFNESGFPGASAPGAGDVAPIE 1842
Query: 13909 EFNMQQMTSMHDDSTTFTNPVYELEDVDMSSPPPSND---------QPSTSASAMSPNRP 14061
+N+Q + + + + F NP+Y+ ++ P + +PS +M +
Sbjct: 1843 GYNLQTVNA--NKARDFANPMYDAVQSGTTADPGMGNGSGIYDVPGEPSAKVKSMGHHAG 1900
Query: 14062 S--TSAASSFVPPTF----DQDEIELKTADEIIVPKAEISK 14166
T AS+ + P+ +++L+T + + P A+ K
Sbjct: 1901 GSFTEPASAIIAPSSITHKASPQLQLRTRE--LDPSADTGK 1939
Score = 443 bits (1140), Expect = e-122
Identities = 368/1377 (26%), Positives = 585/1377 (41%), Gaps = 101/1377 (7%)
Frame = +1
Query: 7198 CQITDNLRKSP--CTQLCFATPGTQTPTCSCARGVLKGR----TCEEPDT---YIMFSDG 7350
C D + P C+Q C TPG C C + + TC+ D +++F++
Sbjct: 470 CADVDECLEQPGACSQHCSNTPGGFY--CKCDETYYERQNDEHTCKRKDKIPPWLIFTNK 527
Query: 7351 DKIIDVAIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNA 7530
+ +++++ ++ N+ D D+ +YF + + + + +
Sbjct: 528 YYVRNMSVD-----GHQYNLMHQDLMNVVALDFDIREEYMYFCDVTAKTIFRAKYGEADD 582
Query: 7531 ENPRLVFGASKQPHAKEIRH----ISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTI 7698
E P IRH + + +DW+ +K+Y+ + + G T+
Sbjct: 583 EMP--------PEREAVIRHDSHGLEGIAIDWVGRKLYWLDRHSKNLDVSELDGSKRKTL 634
Query: 7699 ASGDWT-YALAIDPCSGLLF---WSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISL 7866
SG A+ + P G L+ W Y G+ + SN SR + ++ I+
Sbjct: 635 RSGVVDPRAIVVHPGIGYLYFTSWHLQAYIAKMGM-----DGSNF---SRILNWNDGIAW 686
Query: 7867 PAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGYRAK---SLDIWDRWLYMSDP 8037
P A+++D+ +IYWAD + I AD +G++R + SG + +L ++D ++Y SD
Sbjct: 687 PNALSIDYFTDRIYWADAHLDYIAYADLEGRHRHTVLSGSKVPHVFALSLFDDYIYWSDW 746
Query: 8038 LSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGC 8217
+ R +K G+ + + P D+ + + + C T+NGGC
Sbjct: 747 NLKAIVRANKFHGANYTVLRNTTHRP---------YDLHINHPLRQLPYTNPCGTNNGGC 797
Query: 8218 DQLCTV----------VADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSEPA 8367
LC + + I A +C+C + + L +D T CV + +
Sbjct: 798 SHLCLIAPPPESTYLNIEGYIEEGAPIFKCACPNQFYL----ARDMKT-CVANCTAGQ-- 850
Query: 8368 KECLPPYNFQCG--DGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCI 8541
CG D CI CD + DC D SDE P C R C C N C
Sbjct: 851 --------HLCGGRDEKCIPWFWKCDGEKDCKDGSDE-PATCAPRHCRAGTFQCKNTNCT 901
Query: 8542 DSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPC-SNGHCINQTKVCDGHNDCHDEQVSD 8718
SA C+ +DDCGD SDE +C + C F C S+G CI + CDG DC D SD
Sbjct: 902 PSATICDGVDDCGDRSDEQNCD--LPCPLSDFKCKSSGRCILDSWRCDGDADCKDG--SD 957
Query: 8719 ESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYV 8898
E A C D + + C N CI +CD +DCGD +DE C + C +
Sbjct: 958 EDPAVCFKRTCDPK-TEFSCKNGR-CIPQLWMCDFDNDCGDDSDEPAYMCRQRNCTTGWQ 1015
Query: 8899 RCP---SGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRA 9069
RCP + RCIP+ CDG +DC D DE NC C + F+C N +CI +
Sbjct: 1016 RCPGQSNYRCIPKWLFCDGKDDCRDNSDELPENCPK------CNPETDFKCGNNRCIPKQ 1069
Query: 9070 FIXXXXXXXXXXXXXHSRHGCGN-RTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTC 9246
++ + G R C++ EF C + +CI W CD + C
Sbjct: 1070 WMCDFADDCGDASDENEAVCKGRYRECSESEFRCGNG--------KCISSRWQCDHEDDC 1121
Query: 9247 AGGEDESTELCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQP 9426
DE E +C G F+C++ HCI S + CDGD DC D SDE C P
Sbjct: 1122 GDNSDE----MHCEGYQCKNGTFQCASGHCIASYFRCDGDRDCRDMSDE------VGCPP 1171
Query: 9427 DF----------FQCANHKCVPNSWKCDGNDDCEDGSDEKD--CPKNSASAQKASKCSN- 9567
F FQC N+ CV S CDG DDC DGSDE C + + +CSN
Sbjct: 1172 RFPGGRYCPESRFQCNNNLCVSLSDLCDGTDDCGDGSDEDPSVCSDFNCDTLRRFQCSNE 1231
Query: 9568 -------------------------------------GQFQCTSGECIDDAKVCDRNFDC 9636
Q+QC + CI+ ++VCD + DC
Sbjct: 1232 RCVARYQICDGVDNCGDGSDENNMTLCASKQKPCDLYTQYQCANKHCIERSQVCDFSDDC 1291
Query: 9637 TDRSDESSLCFIDECSLAEKPLCEQKCMDMKI-GYKCDCFEGFAIDISDQKSCHNVNECY 9813
D SDE CS A + C+Q C ++ GY C C+ G+ I ++K C +V+EC
Sbjct: 1292 GDASDELGCHHTSSCSEANRGGCQQHCHNLTDGGYICTCYPGYIIAADNKKKCSDVDECL 1351
Query: 9814 EGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDG 9993
CS +C + G+Y C C +G+ L+ R E E + L N IR ++
Sbjct: 1352 TRQHTCSHQCHNLNGTYSCSCREGFHLTDGASGVCRAEKE-DVILLFVNGQEIRGLNWHK 1410
Query: 9994 NKYELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLR---VDLDEMDSPLSSYETVLRHN 10164
++ + +LD D ++ + D + R V+ + + + + +
Sbjct: 1411 SEEFAVIAAEKRIEALDYDAQQQIVFWADSYDKTIKRSYMVNAIDGRAKIGFAQDLNMKG 1470
Query: 10165 VYGTEGIAVDWVGRKLYML------NRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHP 10326
+AVDW+ LY ++ + V + DGR+ ++++ ++ P +I V+P
Sbjct: 1471 GSKPTAVAVDWLASNLYWTEMDRTGSKPRGRVMVAKTDGRYRRSIVNAGLEVPTSIAVNP 1530
Query: 10327 GKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDR-LFWGDA 10503
G +++++ P I +DGS + + I ++ H P + IDY D ++W D
Sbjct: 1531 QLGRIYWSDAGSAPKIEVSWMDGS-KRRPLITEMIRH----PAGLTIDYSQDHIIYWVDT 1585
Query: 10504 HLNEIGFMDFDGNGRRHI-PAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETI 10680
LN I M DG+ R+ I + H S+ +F+ ++W + E++R DK+ + +
Sbjct: 1586 KLNAIESMRADGSRRKAIVRGDQLRHPVSLDLFESNMFWMTRDTGELVRQDKFGRGVQVV 1645
Query: 10681 LKKTVQLPNDLRIVHPMR-QPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPD-QFVLLS 10854
L + + P+ L++ H R + PNPC +N CSHLCL+ G G+ C+CPD S
Sbjct: 1646 LHRYIVNPSGLKVYHDKRYNTSLPNPC--DNSTCSHLCLLVPG--GHRCACPDASGPPPS 1701
Query: 10855 DQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGE 11025
+ T E C + + P++ C C++ D GE +C R VGE
Sbjct: 1702 HRSTAEVICN-----AAAEHPRPAPRICPCQNGGLCKE--DAQGELLCECRTQFVGE 1751
Score = 374 bits (959), Expect = e-101
Identities = 263/854 (30%), Positives = 377/854 (43%), Gaps = 91/854 (10%)
Frame = +1
Query: 3070 AKCACRQGFMINK----ENNHSC----QKDPAEKIEQLCSSNSTQFQCKNGRCIPKEWKC 3225
+K C+ G I++ + + C +DP CS N +F+C NGRCI K WKC
Sbjct: 12 SKFYCKNGRCISRMWSCDGDDDCGDNSDEDPNYCAYHSCSPN--EFRCNNGRCIFKSWKC 69
Query: 3226 DGENDCLDESDEI--------------------------------------DEKGDKCFH 3291
D ENDC D SDE+ DE ++C
Sbjct: 70 DHENDCKDGSDELGCVYPPCVDGEFTCANGRCIPQAQVCNGVNDCKDNATSDETHERCPM 129
Query: 3292 ETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNHR 3471
T C N +KC T C+ +C GQ+ C F+C NHR
Sbjct: 130 NTTCPANHLKCEKTNICVEPYWLCDGDNDCGDNSDEDPLHC--GQR-TCPTNSFRCPNHR 186
Query: 3472 CIPEQWKXXXXXXXXXXXXEKLEMCGNA--TCAANQFSCANGRCIPIYWLCDGDNDCYDG 3645
CIP W E + C + TC + F+C NG CIP ++CDGDNDC D
Sbjct: 187 CIPATWYCDGDDDCGDGADEPPDYCKSEGRTCFGDLFTCDNGNCIPRIYICDGDNDCLDN 246
Query: 3646 TDED-KERCPPVQCSA-LQFRCANGR-----QCVPLR---NHXXXXXXXXXXXXXXXXAV 3795
+DED + +C +C +F C + QC+P + +
Sbjct: 247 SDEDNRHQCNDRKCDEETEFTCVENKSWQRAQCIPKKWICDGDPDCVDGADENTTLHNCA 306
Query: 3796 TAESCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKCGNGRC 3975
T + C D F C +G CI W +DE KF + + CS+ +F C N +C
Sbjct: 307 TQQPCGEDMFTC-GNGRCINKGWICDHDNDCGDGTDEGKFCNSKYKTCSAQEFTCQNFKC 365
Query: 3976 ILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDGKTH 4155
I N CDGE+DCGD SDE GC + CP AC N Q CI + +C+
Sbjct: 366 IRNQSRCDGEDDCGDHSDEV---GC--AKENITCPQGQFACTNGQ--CIDYNLVCNKYPD 418
Query: 4156 CPGGTDEGGRCARDLCSADRAG-CSFKCHNSPNGPICSCPFGEQLVNKTK-CEPENECLD 4329
C +DE C D C+ C KC ++ G C C G +L+ K C +ECL+
Sbjct: 419 CADESDEPAHCNVDECAKVEINQCGHKCVDTLTGYYCDCNEGYKLLADGKACADVDECLE 478
Query: 4330 S-SSCSQRCKDEKHGFTCSCDEGY-ELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKL 4503
+CSQ C + GF C CDE Y E D+ TCK D + I+ N+ Y + +
Sbjct: 479 QPGACSQHCSNTPGGFYCKCDETYYERQNDEHTCKRKDKIPPWLIFT---NKYYVRNMSV 535
Query: 4504 DNWHTFGAIVE---NAIALAWDSLTDRIYWSDIREKKILSANRNGTNATV------FIAD 4656
D H + + + N +AL +D + +Y+ D+ K I A + + I
Sbjct: 536 DG-HQYNLMHQDLMNVVALDFDIREEYMYFCDVTAKTIFRAKYGEADDEMPPEREAVIRH 594
Query: 4657 GLDITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGV 4836
EGIA+DWVGR LYW+D ++V+ L+ K++TL V PR I V P G
Sbjct: 595 DSHGLEGIAIDWVGRKLYWLDRHSKNLDVSELDGSKRKTL--RSGVVDPRAIVVHPGIGY 652
Query: 4837 MFWTDWGQNPCIERASMDGTDRQIIVKTK--IYWPNTIALDYTTDRVYFADSKLDFIDFV 5010
+++T W I + MDG++ I+ I WPN +++DY TDR+Y+AD+ LD+I +
Sbjct: 653 LYFTSWHLQAYIAKMGMDGSNFSRILNWNDGIAWPNALSIDYFTDRIYWADAHLDYIAYA 712
Query: 5011 NYDGSGRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFS 5190
+ +G R VL+ SK V H AL++F+D +Y+SD L+ + K+ +G +T
Sbjct: 713 DLEGRHRHTVLSGSK-VPHVFALSLFDDYIYWSDWNLKAIVRANKF-HGANYTVLRNTTH 770
Query: 5191 KALGVVAVHPVLQPVIKNNPCSTN--PCSHLCLL----------------NNKNTFTCKC 5316
+ + HP L+ + NPC TN CSHLCL+ F C C
Sbjct: 771 RPYDLHINHP-LRQLPYTNPCGTNNGGCSHLCLIAPPPESTYLNIEGYIEEGAPIFKCAC 829
Query: 5317 PMGEKLDASGKKCI 5358
P L K C+
Sbjct: 830 PNQFYLARDMKTCV 843
Score = 340 bits (873), Expect = 5e-91
Identities = 315/1207 (26%), Positives = 480/1207 (39%), Gaps = 183/1207 (15%)
Frame = +1
Query: 2275 VECDVHGNSFFYADIMDNTIYRIR-PDGEGAAP----VLVTHND-GLFSMSFDWISKQLY 2436
++ D+ ++ D+ TI+R + + + P ++ H+ GL ++ DW+ ++LY
Sbjct: 553 LDFDIREEYMYFCDVTAKTIFRAKYGEADDEMPPEREAVIRHDSHGLEGIAIDWVGRKLY 612
Query: 2437 YVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKGLLFYAEAMRPAAI 2616
++D +L+V ++ D R+ L + + DP ++VVHP G L++ A I
Sbjct: 613 WLDRHSKNLDVSEL--------DGSKRKTLRSGVVDPRAIVVHPGIGYLYFTSWHLQAYI 664
Query: 2617 YRCHIDGQNCQVIRNTTLGR--PSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVKLDI 2790
+ +DG N I N G P+ ++ID+ +R+ W D L I+ D +G++ +
Sbjct: 665 AKMGMDGSNFSRILNWNDGIAWPNALSIDYFTDRIYWADAHLDYIAYADLEGRHRHTVLS 724
Query: 2791 DNPIP--VAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQ 2964
+ +P A+++ ++YIY+ +I R +K +G ++R + H
Sbjct: 725 GSKVPHVFALSLFDDYIYWSDWNLKAIVRANKFHGANYTVLRNTTHRPYDL-------HI 777
Query: 2965 NQPIPDDSREHPCRASQ--CTQLCF-ATPSESHPNELEA---------KCACRQGFMINK 3108
N P+ +PC + C+ LC A P ES +E KCAC F + +
Sbjct: 778 NHPLRQLPYTNPCGTNNGGCSHLCLIAPPPESTYLNIEGYIEEGAPIFKCACPNQFYLAR 837
Query: 3109 ENNHSCQKDPAEKIEQLCSSNST--QFQC--KNGRCIPKEWKCDGENDCLDESDEIDEKG 3276
+ + C +N T Q C ++ +CIP WKCDGE DC D SDE
Sbjct: 838 DM-------------KTCVANCTAGQHLCGGRDEKCIPWFWKCDGEKDCKDGSDEPATCA 884
Query: 3277 DKCFHETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPV-----CA 3441
+ C T +C+NT C P+ V C D C
Sbjct: 885 PR-----HCRAGTFQCKNTN-CTPS-----------ATICDGVDDCGDRSDEQNCDLPCP 927
Query: 3442 AKKFQCDNH-RCIPEQWKXXXXXXXXXXXXEKLEMCGNATC-AANQFSCANGRCIPIYWL 3615
F+C + RCI + W+ E +C TC +FSC NGRCIP W+
Sbjct: 928 LSDFKCKSSGRCILDSWRCDGDADCKDGSDEDPAVCFKRTCDPKTEFSCKNGRCIPQLWM 987
Query: 3616 CDGDNDCYDGTDEDKERCPPVQCSALQFRCA--NGRQCVPLRNHXXXXXXXXXXXXXXXX 3789
CD DNDC D +DE C C+ RC + +C+P
Sbjct: 988 CDFDNDCGDDSDEPAYMCRQRNCTTGWQRCPGQSNYRCIP--KWLFCDGKDDCRDNSDEL 1045
Query: 3790 AVTAESCTPD-QFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSG-RQCSSDQFKCG 3963
C P+ FKC + CIP W SDE + C R+CS +F+CG
Sbjct: 1046 PENCPKCNPETDFKC-GNNRCIPKQWMCDFADDCGDASDENEAVCKGRYRECSESEFRCG 1104
Query: 3964 NGRCILNNWLCDGENDCGDGSDE------------------------------------S 4035
NG+CI + W CD E+DCGD SDE S
Sbjct: 1105 NGKCISSRWQCDHEDDCGDNSDEMHCEGYQCKNGTFQCASGHCIASYFRCDGDRDCRDMS 1164
Query: 4036 SERGCKTSM-NARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGGRCARDL-CSA 4209
E GC R CP C N+ C+ L LCDG C G+DE D C
Sbjct: 1165 DEVGCPPRFPGGRYCPESRFQCNNN--LCVSLSDLCDGTDDCGDGSDEDPSVCSDFNCDT 1222
Query: 4210 DRAGCSFKCHNS---PNGPIC----SCPFGEQLVNKTKCEPENE---------------- 4320
R F+C N IC +C G N T C + +
Sbjct: 1223 LR---RFQCSNERCVARYQICDGVDNCGDGSDENNMTLCASKQKPCDLYTQYQCANKHCI 1279
Query: 4321 --------------------CLDSSSCSQR----CKDEKH-----GFTCSCDEGYELDVD 4413
C +SSCS+ C+ H G+ C+C GY + D
Sbjct: 1280 ERSQVCDFSDDCGDASDELGCHHTSSCSEANRGGCQQHCHNLTDGGYICTCYPGYIIAAD 1339
Query: 4414 -KRTCKVADNVKDTRIYVS----NRNRIYYSD-----HKLD------------------- 4506
K+ C D + S N N Y H D
Sbjct: 1340 NKKKCSDVDECLTRQHTCSHQCHNLNGTYSCSCREGFHLTDGASGVCRAEKEDVILLFVN 1399
Query: 4507 -------NWH---TFGAIV--ENAIALAWDSLTDRIYWSDIREKKI---LSANRNGTNAT 4641
NWH F I + AL +D+ ++W+D +K I N A
Sbjct: 1400 GQEIRGLNWHKSEEFAVIAAEKRIEALDYDAQQQIVFWADSYDKTIKRSYMVNAIDGRAK 1459
Query: 4642 VFIADGLDITEG-----IALDWVGRNLYWVD------SSLNTIEVANLEDPKQRTLLVHQ 4788
+ A L++ G +A+DW+ NLYW + + VA D + R +V+
Sbjct: 1460 IGFAQDLNMKGGSKPTAVAVDWLASNLYWTEMDRTGSKPRGRVMVAK-TDGRYRRSIVNA 1518
Query: 4789 NVSQPRGIAVDPRKGVMFWTDWGQNPCIERASMDGTDRQIIVKTKIYWPNTIALDYTTDR 4968
+ P IAV+P+ G ++W+D G P IE + MDG+ R+ ++ I P + +DY+ D
Sbjct: 1519 GLEVPTSIAVNPQLGRIYWSDAGSAPKIEVSWMDGSKRRPLITEMIRHPAGLTIDYSQDH 1578
Query: 4969 -VYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPK 5145
+Y+ D+KL+ I+ + DGS R ++ + ++HP +L +FE M++ R +L K
Sbjct: 1579 IIYWVDTKLNAIESMRADGSRRKAIVRGDQ-LRHPVSLDLFESNMFWMTRDTGELVRQDK 1637
Query: 5146 YPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTNPCSHLCLLNNKNTFTCKCPMG 5325
+ G + + + G+ H NPC + CSHLCLL C CP
Sbjct: 1638 FGRGVQVVLHRYIVNPS-GLKVYHDKRYNTSLPNPCDNSTCSHLCLL-VPGGHRCACP-- 1693
Query: 5326 EKLDASG 5346
DASG
Sbjct: 1694 ---DASG 1697
Score = 290 bits (743), Expect = 5e-76
Identities = 206/683 (30%), Positives = 318/683 (46%), Gaps = 35/683 (5%)
Frame = +1
Query: 157 CN-ENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPG----CKSDQWQCDTYTWHSV 321
CN E DF+C + +CI +W G C +++C +
Sbjct: 1052 CNPETDFKCGNNRCIPKQWMCDFADDCGDASDENEAVCKGRYRECSESEFRCG-----NG 1106
Query: 322 SCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRD 501
CI+ +CD+ DC D SDE C C + F CA G C +CDG DCRD
Sbjct: 1107 KCISSRWQCDHEDDCGDNSDEMHCEG--YQCKN-GTFQCASGH-CIASYFRCDGDRDCRD 1162
Query: 502 LSDEKDSCSR--NHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDE-PDTCEFKKC- 669
+SDE R C + +F+C + C+ S +CDG+ DC DGSDE P C C
Sbjct: 1163 MSDEVGCPPRFPGGRYCPESRFQC-NNNLCVSLSDLCDGTDDCGDGSDEDPSVCSDFNCD 1221
Query: 670 TANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDE---CGEYRCPPG---KWNCPGTGHCID 831
T FQC N+RC R CD D+CGD SDE+ C + P ++ C HCI+
Sbjct: 1222 TLRRFQCSNERCVARYQICDGVDNCGDGSDENNMTLCASKQKPCDLYTQYQCANK-HCIE 1280
Query: 832 QLKLCDGSKDCADGADEQQCSQNLCPSL----GCQAGCHPSPHGGE-CTCPSGYKLDDRF 996
+ ++CD S DC D +DE C S GCQ CH GG CTC GY +
Sbjct: 1281 RSQVCDFSDDCGDASDELGCHHTSSCSEANRGGCQQHCHNLTDGGYICTCYPGYIIAADN 1340
Query: 997 HRTCSDINECAEFGY-CDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNN 1173
+ CSD++EC + C C N ++CSC + G G C +
Sbjct: 1341 KKKCSDVDECLTRQHTCSHQCHNLNGTYSCSCREG---FHLTDGAS-------GVCRAEK 1390
Query: 1174 ADKMKLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDR----LAHS 1341
D + LFV +E + LN + EE +A+ + I +D+D + +FW D + S
Sbjct: 1391 EDVILLFVNGQE-IRGLN-WHKSEEFAVIAAEKRIEALDYDAQQQIVFWADSYDKTIKRS 1448
Query: 1342 AFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIE---SGSR---RIDVSSYD 1503
+D +I + L++K P +AVDW+ + LY E +GS+ R+ V+ D
Sbjct: 1449 YMVNAIDGRAKIGFAQDLNMKGGSKPTAVAVDWLASNLYWTEMDRTGSKPRGRVMVAKTD 1508
Query: 1504 GERRTVLLADGLTLPLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVS 1674
G R ++ GL +P IA++P G ++++ + K+E + MDG+ RR L+ +
Sbjct: 1509 GRYRRSIVNAGLEVPTSIAVNPQLGRIYWSDAGSAPKIEVSWMDGSKRRPLITEMIRHPA 1568
Query: 1675 GIVVDITAKR-VYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDW 1851
G+ +D + +YWVD K++ +ES+ G+ R+ + +G + + HP L LF+ ++W
Sbjct: 1569 GLTIDYSQDHIIYWVDTKLNAIESMRADGSRRKAIVRG-DQLRHPVSLDLFESNMFWMTR 1627
Query: 1852 TRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNAD 2031
+++ +KFG +++ N P G+ YH + + NPC N+
Sbjct: 1628 DTGELVRQDKFGRGVQVVLHRYIVN--PSGLKVYH---------DKRYNTSLPNPCDNST 1676
Query: 2032 CEGMCILSKDNGGFGVGYKCACP 2100
C +C+L G++CACP
Sbjct: 1677 CSHLCLLVPG------GHRCACP 1693
Score = 288 bits (737), Expect = 3e-75
Identities = 238/896 (26%), Positives = 359/896 (39%), Gaps = 107/896 (11%)
Frame = +1
Query: 11233 LCMSAERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXETPE-CAQIECKKGWTRCS-- 11403
+C C A +F C N +CI++ W E P CA C RC+
Sbjct: 1 MCAPRNNTCEASKFYCKNGRCISRMWSCDGDDDCGDNSDEDPNYCAYHSCSPNEFRCNNG 60
Query: 11404 ------------------------------------SSYRCIPNWAFCNGQDDCRDN--S 11469
++ RCIP CNG +DC+DN S
Sbjct: 61 RCIFKSWKCDHENDCKDGSDELGCVYPPCVDGEFTCANGRCIPQAQVCNGVNDCKDNATS 120
Query: 11470 DEDKQRCP--TCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSES 11643
DE +RCP T +C + C+ W+CD +NDCGDNSDE CG R C +
Sbjct: 121 DETHERCPMNTTCPANHLKCEKTNICVEPYWLCDGDNDCGDNSDEDPLHCG--QRTCPTN 178
Query: 11644 EFRCNDGKCIPGSKVCDGTIQCSDGLDE----SQCTLRRCLPGHRQCDDGTCIAEHKWCD 11811
FRC + +CIP + CDG C DG DE + R C CD+G CI CD
Sbjct: 179 SFRCPNHRCIPATWYCDGDDDCGDGADEPPDYCKSEGRTCFGDLFTCDNGNCIPRIYICD 238
Query: 11812 RKKDCPNAADELHCEDVSRRTC-SPFEFECA------NSVCIPRKFMXXXXXXXXXXSDE 11970
DC + +DE + + R C EF C + CIP+K++ +DE
Sbjct: 239 GDNDCLDNSDEDNRHQCNDRKCDEETEFTCVENKSWQRAQCIPKKWICDGDPDCVDGADE 298
Query: 11971 --TSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSFSEYGD 12144
T C + Q F C + R C+N +C+ NDCG D +DE C+ S+Y
Sbjct: 299 NTTLHNCATQQPCGEDMFTCGNGR-CINKGWICDHDNDCG--DGTDEG-KFCN--SKYKT 352
Query: 12145 CSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHG-----GKTSCE---------- 12279
CS+ +F C N KC+ CD +DDCGD SDE+GC+K G+ +C
Sbjct: 353 CSAQEFTCQNFKCIRNQSRCDGEDDCGDHSDEVGCAKENITCPQGQFACTNGQCIDYNLV 412
Query: 12280 ----------------------AFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECI 12393
A C H C D G+YC C +G++ K C
Sbjct: 413 CNKYPDCADESDEPAHCNVDECAKVEINQCGHKCVDTLTGYYCDCNEGYKLLADG-KACA 471
Query: 12394 DIDECAGN-NTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADD 12570
D+DEC C+Q C NT G + C+C E Y C+ K +I +
Sbjct: 472 DVDECLEQPGACSQHCSNTPGGFYCKCDETYYER----QNDEHTCKRKDKIPPWLIFTNK 527
Query: 12571 SLVQ-LSLHGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERTIYRSAIANGNQ 12747
V+ +S+ G H R+E MY+ D + +TI+R+ +
Sbjct: 528 YYVRNMSVDG-----HQYNLMHQDLMNVVALDFDIREEYMYFCDVTAKTIFRAKYGEADD 582
Query: 12748 SHEGQK-LDVDFAAMGVVPTAIAVDYTTGNLF-IAAVSENIENGLVTARKKRMSEPIDNQ 12921
++ + + G+ IA+D+ L+ + S+N++
Sbjct: 583 EMPPEREAVIRHDSHGL--EGIAIDWVGRKLYWLDRHSKNLD------------------ 622
Query: 12922 NTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQ 13101
V DG K + +G + P A++ P G + ++ L A I MDG++
Sbjct: 623 ------VSELDGSKRKTLRSG-VVDPRAIVVHPGIGYLYFTSWHLQAYIAKMGMDGSNFS 675
Query: 13102 IIV--KDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHIP--YAV 13269
I+ D + P +++ID +RIYW D + +++G R TV+ +P +A+
Sbjct: 676 RILNWNDGIAWPNALSIDYFT-DRIYWADAHLDYIAYADLEGRHRHTVLSGSKVPHVFAL 734
Query: 13270 DVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCER 13449
+F+++IYW K + +KF +VL + + + ++ + G
Sbjct: 735 SLFDDYIYWSDWNLKAIVRANKFHGANYTVLRNTTHRPYDLHINHPLRQLPYTNPCGTNN 794
Query: 13450 AQCSHLCVSLPSTGFACLCPDGIV----PQLDGSCATQHVEALTMPKQC--KCTNG 13599
CSHLC+ P L +G + P +C Q A M K C CT G
Sbjct: 795 GGCSHLCLIAPPPESTYLNIEGYIEEGAPIFKCACPNQFYLARDM-KTCVANCTAG 849
Score = 281 bits (719), Expect = 3e-73
Identities = 204/692 (29%), Positives = 306/692 (43%), Gaps = 44/692 (6%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQC--DTYTWHSVSCI 330
C N FRC + +CI W P CKS+ C D +T + +CI
Sbjct: 175 CPTNSFRCPNHRCIPATWYCDGDDDCGDGADE---PPDYCKSEGRTCFGDLFTCDNGNCI 231
Query: 331 AEYQRCDNITDCADGSDEKDC-PASTVDCSSQNVFMCADGR-----QCFDVSKKCDGKYD 492
CD DC D SDE + + C + F C + + QC CDG D
Sbjct: 232 PRIYICDGDNDCLDNSDEDNRHQCNDRKCDEETEFTCVENKSWQRAQCIPKKWICDGDPD 291
Query: 493 CRDLSDEKDSCSRNHTA--CFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTC--EF 660
C D +DE + T C + F C + +CI K W+CD DC DG+DE C ++
Sbjct: 292 CVDGADENTTLHNCATQQPCGEDMFTCGNG-RCINKGWICDHDNDCGDGTDEGKFCNSKY 350
Query: 661 KKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGE--YRCPPGKWNCPGTGHCIDQ 834
K C+A EF C+N +C + RCD DDCGD+SDE C + CP G++ C G CID
Sbjct: 351 KTCSAQEFTCQNFKCIRNQSRCDGEDDCGDHSDEVGCAKENITCPQGQFACT-NGQCIDY 409
Query: 835 LKLCDGSKDCADGADE-QQCSQNLCPSL---GCQAGCHPSPHGGECTCPSGYKLDDRFHR 1002
+C+ DCAD +DE C+ + C + C C + G C C GYKL +
Sbjct: 410 NLVCNKYPDCADESDEPAHCNVDECAKVEINQCGHKCVDTLTGYYCDCNEGYKL-LADGK 468
Query: 1003 TCSDINECAEF-GYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNAD 1179
C+D++EC E G C Q C+N GF C C + Q + K + + + N
Sbjct: 469 ACADVDECLEQPGACSQHCSNTPGGFYCKCDETYYERQNDEHTCKRKDKIPPWLIFTNK- 527
Query: 1180 KMKLFVARREGLYRLNPKNPDEEVKKLASGEF--IYGIDFDYGDRKIFWTDRLAHSAFSA 1353
Y + + D L + + +DFD + +++ D A + F A
Sbjct: 528 ------------YYVRNMSVDGHQYNLMHQDLMNVVALDFDIREEYMYFCDVTAKTIFRA 575
Query: 1354 ---DVDDE--GEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRT 1518
+ DDE E + + L +A+DW+ LY ++ S+ +DVS DG +R
Sbjct: 576 KYGEADDEMPPEREAVIRHDSHGL---EGIAIDWVGRKLYWLDRHSKNLDVSELDGSKRK 632
Query: 1519 VLLADGLTLPLDIALDPLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHTHQV--SGIV 1683
L G+ P I + P G ++FT+ Q + MDG+N ++N + + +
Sbjct: 633 T-LRSGVVDPRAIVVHPGIGYLYFTSWHLQAYIAKMGMDGSNFSRILNWNDGIAWPNALS 691
Query: 1684 VDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLG 1863
+D R+YW D +D + D +G R V G + VPH F L+LFD Y+YW+DW
Sbjct: 692 IDYFTDRIYWADAHLDYIAYADLEGRHRHTVLSG-SKVPHVFALSLFDDYIYWSDWNLKA 750
Query: 1864 VIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPC--TNADCE 2037
+++ KF + NT + + + I+ HP+ Q + NPC N C
Sbjct: 751 IVRANKFHGANYTVLRNTTHRPYDLHIN--HPLRQ----------LPYTNPCGTNNGGCS 798
Query: 2038 GMCILSKD--------NGGFGVG---YKCACP 2100
+C+++ G G +KCACP
Sbjct: 799 HLCLIAPPPESTYLNIEGYIEEGAPIFKCACP 830
Score = 156 bits (394), Expect = 2e-35
Identities = 100/327 (30%), Positives = 138/327 (41%), Gaps = 12/327 (3%)
Frame = +1
Query: 3436 CAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNATCAANQFSCANGRCIPIYWL 3615
C A KF C N RCI W E C +C+ N+F C NGRCI W
Sbjct: 9 CEASKFYCKNGRCISRMWSCDGDDDCGDNSDEDPNYCAYHSCSPNEFRCNNGRCIFKSWK 68
Query: 3616 CDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQCVP---LRNHXXXXXXXXXXXXXXX 3786
CD +NDC DG+DE PP C +F CANGR C+P + N
Sbjct: 69 CDHENDCKDGSDELGCVYPP--CVDGEFTCANGR-CIPQAQVCNGVNDCKDNATSDETHE 125
Query: 3787 XAVTAESCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKCGN 3966
+C + KC + +C+ W SDE C R C ++ F+C N
Sbjct: 126 RCPMNTTCPANHLKCEKTNICVEPYWLCDGDNDCGDNSDEDPLHC-GQRTCPTNSFRCPN 184
Query: 3967 GRCILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDG 4146
RCI W CDG++DCGDG+DE + CK+ R C + C+N CIP +CDG
Sbjct: 185 HRCIPATWYCDGDDDCGDGADEPPDY-CKS--EGRTCFGDLFTCDNG--NCIPRIYICDG 239
Query: 4147 KTHCPGGTDEGGR--CARDLCSADRAGCSFKCHNSPNGPICSCPFGEQLVNKTKCEPENE 4320
C +DE R C C + F C + + C + K C+ + +
Sbjct: 240 DNDCLDNSDEDNRHQCNDRKCDEE---TEFTCVENKSWQRAQC-----IPKKWICDGDPD 291
Query: 4321 CLDSS-------SCSQRCKDEKHGFTC 4380
C+D + +C+ + + FTC
Sbjct: 292 CVDGADENTTLHNCATQQPCGEDMFTC 318
Score = 152 bits (384), Expect = 2e-34
Identities = 110/340 (32%), Positives = 149/340 (43%), Gaps = 36/340 (10%)
Frame = +1
Query: 157 CNENDFRC-NDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVS--- 324
C +DF+C + G+CI W P K CD T S
Sbjct: 926 CPLSDFKCKSSGRCILDSWRCDGDADCKDGSDED--PAVCFKRT---CDPKTEFSCKNGR 980
Query: 325 CIAEYQRCDNITDCADGSDE-------KDCPASTVDCSSQNVFMCADGRQCFDVSKKCDG 483
CI + CD DC D SDE ++C C Q+ + C + F CDG
Sbjct: 981 CIPQLWMCDFDNDCGDDSDEPAYMCRQRNCTTGWQRCPGQSNYRCIP-KWLF-----CDG 1034
Query: 484 KYDCRDLSDE-KDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTC-- 654
K DCRD SDE ++C + + + F+C + +CI K W+CD + DC D SDE +
Sbjct: 1035 KDDCRDNSDELPENCPKCNP---ETDFKCGNN-RCIPKQWMCDFADDCGDASDENEAVCK 1090
Query: 655 -EFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCID 831
+++C+ +EF+C N +C +++CD+ DDCGDNSDE C Y+C G + C +GHCI
Sbjct: 1091 GRYRECSESEFRCGNGKCISSRWQCDHEDDCGDNSDEMHCEGYQCKNGTFQC-ASGHCIA 1149
Query: 832 QLKLCDGSKDCADGADEQ-----------------QCSQNLCPSLGCQAGCHPSPHGGEC 960
CDG +DC D +DE QC+ NLC SL G
Sbjct: 1150 SYFRCDGDRDCRDMSDEVGCPPRFPGGRYCPESRFQCNNNLCVSLSDLC-------DGTD 1202
Query: 961 TCPSGYKLDDRFHRTCSDINECAEFGYCDQL----CANHR 1068
C G D CSD N CD L C+N R
Sbjct: 1203 DCGDG---SDEDPSVCSDFN-------CDTLRRFQCSNER 1232
Score = 151 bits (381), Expect = 5e-34
Identities = 107/345 (31%), Positives = 148/345 (42%), Gaps = 27/345 (7%)
Frame = +1
Query: 148 SSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXX--PHPGCKSDQWQCDTYTWHSV 321
++ C + F C +G+CI W + C ++++C+ +
Sbjct: 6 NNTCEASKFYCKNGRCISRMWSCDGDDDCGDNSDEDPNYCAYHSCSPNEFRCN-----NG 60
Query: 322 SCIAEYQRCDNITDCADGSDEKDCP-ASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCR 498
CI + +CD+ DC DGSDE C VD F CA+GR C ++ C+G DC+
Sbjct: 61 RCIFKSWKCDHENDCKDGSDELGCVYPPCVD----GEFTCANGR-CIPQAQVCNGVNDCK 115
Query: 499 D--LSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDE-PDTCEFKKC 669
D SDE +T C +C C++ W+CDG DC D SDE P C + C
Sbjct: 116 DNATSDETHERCPMNTTCPANHLKCEKTNICVEPYWLCDGDNDCGDNSDEDPLHCGQRTC 175
Query: 670 TANEFQCKNKRCQPRKFRCDYYDDCGDNSDE--DEC-GEYRCPPGKWNCPGTGHCIDQLK 840
N F+C N RC P + CD DDCGD +DE D C E R G G+CI ++
Sbjct: 176 PTNSFRCPNHRCIPATWYCDGDDDCGDGADEPPDYCKSEGRTCFGDLFTCDNGNCIPRIY 235
Query: 841 LCDGSKDCADGADE---QQCSQNLC---PSLGC-------QAGCHPSPH--GGECTCPSG 975
+CDG DC D +DE QC+ C C +A C P G+ C G
Sbjct: 236 ICDGDNDCLDNSDEDNRHQCNDRKCDEETEFTCVENKSWQRAQCIPKKWICDGDPDCVDG 295
Query: 976 YKLDDRFHRTCSDINECAEFGYCDQLCANHR---PGFTCSCLGDC 1101
+ H C+ C E + C N R G+ C DC
Sbjct: 296 ADENTTLH-NCATQQPCGEDMF---TCGNGRCINKGWICDHDNDC 336
Score = 145 bits (365), Expect = 4e-32
Identities = 96/291 (32%), Positives = 122/291 (40%), Gaps = 11/291 (3%)
Frame = +1
Query: 3541 MCG--NATCAANQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANG 3714
MC N TC A++F C NGRCI W CDGD+DC D +DED C CS +FRC NG
Sbjct: 1 MCAPRNNTCEASKFYCKNGRCISRMWSCDGDDDCGDNSDEDPNYCAYHSCSPNEFRCNNG 60
Query: 3715 RQCVPLRNHXXXXXXXXXXXXXXXXAVTAESCTPDQFKCVSSGLCIPAS--WKXXXXXXX 3888
R C+ C +F C ++G CIP +
Sbjct: 61 R-CI--FKSWKCDHENDCKDGSDELGCVYPPCVDGEFTC-ANGRCIPQAQVCNGVNDCKD 116
Query: 3889 XXXSDEPKFGCTSGRQCSSDQFKCGNGR-CILNNWLCDGENDCGDGSDESSERGCKTSMN 4065
SDE C C ++ KC C+ WLCDG+NDCGD SDE
Sbjct: 117 NATSDETHERCPMNTTCPANHLKCEKTNICVEPYWLCDGDNDCGDNSDED-----PLHCG 171
Query: 4066 ARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCSFKCHNS 4245
R CP C N + CIP CDG C G DE D C ++ C
Sbjct: 172 QRTCPTNSFRCPNHR--CIPATWYCDGDDDCGDGADE----PPDYCKSEGRTCF------ 219
Query: 4246 PNGPICSCPFGEQLVNKTKCEPENECLDSS------SCSQRCKDEKHGFTC 4380
G + +C G + C+ +N+CLD+S C+ R DE+ FTC
Sbjct: 220 --GDLFTCDNGNCIPRIYICDGDNDCLDNSDEDNRHQCNDRKCDEETEFTC 268
Score = 135 bits (339), Expect = 4e-29
Identities = 114/429 (26%), Positives = 160/429 (36%), Gaps = 67/429 (15%)
Frame = +1
Query: 124 ISASVNTASSVCNENDFRCN--DGKCIRTEWXXXXXXXXXXXXXXXXXPHPG-CKSDQWQ 294
++ + T + C C D KCI W P C++ +Q
Sbjct: 835 LARDMKTCVANCTAGQHLCGGRDEKCIPWFWKCDGEKDCKDGSDEPATCAPRHCRAGTFQ 894
Query: 295 CDTYTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKK 474
C + +C CD + DC D SDE++C + C + F C +C S +
Sbjct: 895 CK-----NTNCTPSATICDGVDDCGDRSDEQNC---DLPCPLSD-FKCKSSGRCILDSWR 945
Query: 475 CDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPD-T 651
CDG DC+D SDE + T + +F C + +CI + W+CD DC D SDEP
Sbjct: 946 CDGDADCKDGSDEDPAVCFKRTCDPKTEFSCKN-GRCIPQLWMCDFDNDCGDDSDEPAYM 1004
Query: 652 CEFKKCTA-------------------------------------------NEFQCKNKR 702
C + CT +F+C N R
Sbjct: 1005 CRQRNCTTGWQRCPGQSNYRCIPKWLFCDGKDDCRDNSDELPENCPKCNPETDFKCGNNR 1064
Query: 703 CQPRKFRCDYYDDCGDNSDEDEC---GEYR-CPPGKWNCPGTGHCIDQLKLCDGSKDCAD 870
C P+++ CD+ DDCGD SDE+E G YR C ++ C G G CI CD DC D
Sbjct: 1065 CIPKQWMCDFADDCGDASDENEAVCKGRYRECSESEFRC-GNGKCISSRWQCDHEDDCGD 1123
Query: 871 GADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFH----RTCSDINECAEFG 1038
+DE C C + G C SG+ + F R C D+++ E G
Sbjct: 1124 NSDEMHCEGYQCKN-------------GTFQCASGHCIASYFRCDGDRDCRDMSD--EVG 1168
Query: 1039 ---------YCDQ---LCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADK 1182
YC + C N+ C L D + G G D C N D
Sbjct: 1169 CPPRFPGGRYCPESRFQCNNN----LCVSLSDLCDGTDDCGDGSDE--DPSVCSDFNCDT 1222
Query: 1183 MKLFVARRE 1209
++ F E
Sbjct: 1223 LRRFQCSNE 1231
Score = 125 bits (314), Expect = 3e-26
Identities = 63/162 (38%), Positives = 85/162 (51%), Gaps = 4/162 (2%)
Frame = +1
Query: 9274 LCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHAN-CTYSSCQPDFFQCANH 9450
+C C +F C N CI W CDGD+DC D SDE N C Y SC P+ F+C N
Sbjct: 1 MCAPRNNTCEASKFYCKNGRCISRMWSCDGDDDCGDNSDEDPNYCAYHSCSPNEFRCNNG 60
Query: 9451 KCVPNSWKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNF 9630
+C+ SWKCD +DC+DGSDE C C +G+F C +G CI A+VC+
Sbjct: 61 RCIFKSWKCDHENDCKDGSDELGC--------VYPPCVDGEFTCANGRCIPQAQVCNGVN 112
Query: 9631 DCTDR--SDES-SLCFIDECSLAEKPLCEQKCMDMKIGYKCD 9747
DC D SDE+ C ++ A CE+ + ++ + CD
Sbjct: 113 DCKDNATSDETHERCPMNTTCPANHLKCEKTNICVEPYWLCD 154
Score = 111 bits (278), Expect = 5e-22
Identities = 60/177 (33%), Positives = 84/177 (46%), Gaps = 2/177 (1%)
Frame = +1
Query: 523 CSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDE-PDTCEFKKCTANEFQCKNK 699
C+ + C +F C + +CI + W CDG DC D SDE P+ C + C+ NEF+C N
Sbjct: 2 CAPRNNTCEASKFYCKNG-RCISRMWSCDGDDDCGDNSDEDPNYCAYHSCSPNEFRCNNG 60
Query: 700 RCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGAD 879
RC + ++CD+ +DC D SDE C C G++ C G CI Q ++C+G DC D A
Sbjct: 61 RCIFKSWKCDHENDCKDGSDELGCVYPPCVDGEFTC-ANGRCIPQAQVCNGVNDCKDNAT 119
Query: 880 EQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAE-FGYCD 1047
+ + CP TCP+ H C N C E + CD
Sbjct: 120 SDETHER-CPM--------------NTTCPAN-------HLKCEKTNICVEPYWLCD 154
Score = 110 bits (275), Expect = 1e-21
Identities = 99/378 (26%), Positives = 163/378 (42%), Gaps = 16/378 (4%)
Frame = +1
Query: 6208 IKALQPRASSSGHPCHINNGNCDHICIPLMFAQRTCTCANGY-VKDGQTS-CKLFDESFV 6381
I A + S C C H C L +C+C G+ + DG + C+ E +
Sbjct: 1336 IAADNKKKCSDVDECLTRQHTCSHQCHNLN-GTYSCSCREGFHLTDGASGVCRAEKEDVI 1394
Query: 6382 IVATKTKVI-GYPIDETQSKGVAMEPIGGLSITGVDYDYESKTIYVAEASGINKGIT-AY 6555
++ + I G +++ V I +DYD + + ++ A++ +K I +Y
Sbjct: 1395 LLFVNGQEIRGLNWHKSEEFAVIAAE---KRIEALDYDAQQQIVFWADS--YDKTIKRSY 1449
Query: 6556 TIGESSPRAVIR-----DSIGSLTIKSLAIDWINYNMYFINHDAE----RTNIEVSKLDG 6708
+ RA I + G ++A+DW+ N+Y+ D R + V+K DG
Sbjct: 1450 MVNAIDGRAKIGFAQDLNMKGGSKPTAVAVDWLASNLYWTEMDRTGSKPRGRVMVAKTDG 1509
Query: 6709 TYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQRSFLDGSRREVIVSSGIAEPTD 6888
YR+ ++ E P+SIAV+P +YW+D G P I+ S++DGS+R +++ I P
Sbjct: 1510 RYRRSIVNAGLEVPTSIAVNPQLGRIYWSDAGSAPKIEVSWMDGSKRRPLITEMIRHPAG 1569
Query: 6889 LVVDVA-SKMIYWSDAKMDGIYRVRSTGGTPE-LVRSD-IASAAGVALHGQNMYWTDNRL 7059
L +D + +IYW D K++ I +R+ G + +VR D + + L NM+W
Sbjct: 1570 LTIDYSQDHIIYWVDTKLNAIESMRADGSRRKAIVRGDQLRHPVSLDLFESNMFWMTRDT 1629
Query: 7060 EKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRASSPCQITDNLRKSPCTQ 7239
+L R ++L V S G +PC DN S C+
Sbjct: 1630 GELVRQDKFGRGVQVVLHRYIVNPS----GLKVYHDKRYNTSLPNPC---DN---STCSH 1679
Query: 7240 LCFATPGTQTPTCSCARG 7293
LC PG C A G
Sbjct: 1680 LCLLVPGGHRCACPDASG 1697
Score = 83.2 bits (204), Expect = 2e-13
Identities = 86/330 (26%), Positives = 143/330 (43%), Gaps = 15/330 (4%)
Frame = +1
Query: 6313 CTCANGYVK--DGQTSCKLFDE--SFVIVATKTKVIGYPIDETQSKGVAMEPIGGLSITG 6480
C C Y + + + +CK D+ ++I K V +D Q + + +++
Sbjct: 496 CKCDETYYERQNDEHTCKRKDKIPPWLIFTNKYYVRNMSVDGHQYNLMHQDL---MNVVA 552
Query: 6481 VDYDYESKTIYVAEASGINKGITAYTIGESSPR------AVIR-DSIGSLTIKSLAIDWI 6639
+D+D + +Y + + K I GE+ AVIR DS G ++ +AIDW+
Sbjct: 553 LDFDIREEYMYFCDVTA--KTIFRAKYGEADDEMPPEREAVIRHDSHG---LEGIAIDWV 607
Query: 6640 NYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTI 6819
+Y++ D N++VS+LDG+ RK L + + P +I V P YLY+ + I
Sbjct: 608 GRKLYWL--DRHSKNLDVSELDGSKRKTLRSGVVD-PRAIVVHPGIGYLYFTSWHLQAYI 664
Query: 6820 QRSFLDGSRREVIVS--SGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPELV-- 6987
+ +DGS I++ GIA P L +D + IYW+DA +D I G V
Sbjct: 665 AKMGMDGSNFSRILNWNDGIAWPNALSIDYFTDRIYWADAHLDYIAYADLEGRHRHTVLS 724
Query: 6988 RSDIASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFS 7167
S + ++L +YW+D L+ + RA +L TT D+ +
Sbjct: 725 GSKVPHVFALSLFDDYIYWSDWNLKAIVRANKFHGANYTVLRNTTHRPY-----DLHINH 779
Query: 7168 SNNQPRASSPCQITDNLRKSPCTQLCFATP 7257
Q ++PC C+ LC P
Sbjct: 780 PLRQLPYTNPC----GTNNGGCSHLCLIAP 805
Score = 63.5 bits (153), Expect = 1e-07
Identities = 79/351 (22%), Positives = 145/351 (40%), Gaps = 17/351 (4%)
Frame = +1
Query: 2083 YKCACPIGQKLVNGKRCIDSID----YLLFSSNKIVRGIFPEINEKALAEAVLPISPISQ 2250
Y C+C G L +G + + LLF + + +RG+ +E+ A ++
Sbjct: 1368 YSCSCREGFHLTDGASGVCRAEKEDVILLFVNGQEIRGLNWHKSEEFAVIA-------AE 1420
Query: 2251 RRIGMYFEVECDVHGNSFFYADIMDNTIYRIRP----DGEG----AAPVLVTHNDGLFSM 2406
+RI ++ D F+AD D TI R DG A + + ++
Sbjct: 1421 KRIEA---LDYDAQQQIVFWADSYDKTIKRSYMVNAIDGRAKIGFAQDLNMKGGSKPTAV 1477
Query: 2407 SFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITE-LRDPVSVVVHPWKGLL 2583
+ DW++ LY+ + R + G + D RR ++ L P S+ V+P G +
Sbjct: 1478 AVDWLASNLYWTEMDRTGSK--PRGRVMVAKTDGRYRRSIVNAGLEVPTSIAVNPQLGRI 1535
Query: 2584 FYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLC-WGDTLLKTISCMDF 2760
++++A I +DG + + + P+ + ID++++ + W DT L I M
Sbjct: 1536 YWSDAGSAPKIEVSWMDGSKRRPLITEMIRHPAGLTIDYSQDHIIYWVDTKLNAIESMRA 1595
Query: 2761 DG---KNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADER 2931
DG K +V+ D PV++ + ++++ + + R K G G ++V R
Sbjct: 1596 DGSRRKAIVRGD-QLRHPVSLDLFESNMFWMTRDTGELVR-QDKFGRGVQVVL-----HR 1648
Query: 2932 SIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCAC 3084
I + + + S +PC S C+ LC P +CAC
Sbjct: 1649 YIVNPSGLKVYHDKRYNTSLPNPCDNSTCSHLCLLVPGGH-------RCAC 1692
Score = 58.5 bits (140), Expect = 5e-06
Identities = 43/172 (25%), Positives = 78/172 (45%), Gaps = 13/172 (7%)
Frame = +1
Query: 5869 AKVARAGLDGSN-PLVIASND-LAELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHY 6042
A +A+ G+DGSN ++ ND +A + ++ID R+Y+++A I+ +G+ RH
Sbjct: 662 AYIAKMGMDGSNFSRILNWNDGIAWPNALSIDYFTDRIYWADAHLDYIAYADLEGRHRHT 721
Query: 6043 VLSDGGRQPN--GLAFYGDRLFYAD---------SAFDSIEVATINGDSQPPQWTHFKKD 6189
VLS G + P+ L+ + D ++++D + F + + P H
Sbjct: 722 VLS-GSKVPHVFALSLFDDYIYWSDWNLKAIVRANKFHGANYTVLRNTTHRPYDLHINHP 780
Query: 6190 VENLANIKALQPRASSSGHPCHINNGNCDHICIPLMFAQRTCTCANGYVKDG 6345
+ L +PC NNG C H+C+ + T GY+++G
Sbjct: 781 LRQLPYT-----------NPCGTNNGGCSHLCLIAPPPESTYLNIEGYIEEG 821
Score = 56.6 bits (135), Expect = 2e-05
Identities = 56/220 (25%), Positives = 75/220 (33%), Gaps = 4/220 (1%)
Frame = +1
Query: 139 NTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHS 318
N+ C+ +F C + KCIR +
Sbjct: 347 NSKYKTCSAQEFTCQNFKCIRNQ------------------------------------- 369
Query: 319 VSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCR 498
RCD DC D SDE C + C Q F C +G QC D + C+ DC
Sbjct: 370 -------SRCDGEDDCGDHSDEVGCAKENITC-PQGQFACTNG-QCIDYNLVCNKYPDCA 420
Query: 499 DLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCD---GSKDCADGSDEPDTCE-FKK 666
D SDE C+ + A + +C K + CD G K ADG D E ++
Sbjct: 421 DESDEPAHCNVDECAKVEIN-QCGHKCVDTLTGYYCDCNEGYKLLADGKACADVDECLEQ 479
Query: 667 CTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRC 786
A C N P F C C + E + E+ C
Sbjct: 480 PGACSQHCSN---TPGGFYC----KCDETYYERQNDEHTC 512
Score = 52.8 bits (125), Expect = 2e-04
Identities = 75/363 (20%), Positives = 142/363 (38%), Gaps = 11/363 (3%)
Frame = +1
Query: 5266 CSHLCLLNNKNTFTCKCPMGEKLD--ASGKKCIDDAKPFLVIIQKTNVFGIEMNSASEKE 5439
CSH C N T++C C G L ASG + L+ + + G+ + + +E
Sbjct: 1357 CSHQCH-NLNGTYSCSCREGFHLTDGASGVCRAEKEDVILLFVNGQEIRGLNWHKS--EE 1413
Query: 5440 TPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIY-RSTVNGGNK 5616
V+A + L YDA + +F + ++ KT+ + +AI R+ +
Sbjct: 1414 FAVIAAEKRIEALD------YDAQQQIVFWAD--SYDKTIKRSYMVNAIDGRAKIGFAQD 1465
Query: 5617 TKMFSSAVPDDAYCLGFDWNGRNLV------VGNKITQTIEIIRTQGKQYRSVILSNDQS 5778
M + P + DW NL G+K + + +T G+ RS++ + +
Sbjct: 1466 LNMKGGSKPT---AVAVDWLASNLYWTEMDRTGSKPRGRVMVAKTDGRYRRSIVNAGLEV 1522
Query: 5779 XXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAID 5958
G ++W D G K+ + +DGS + + + + ID
Sbjct: 1523 PTSIAVNPQL------GRIYWSDAGSAP---KIEVSWMDGSKRRPLITEMIRHPAGLTID 1573
Query: 5959 TTNTRV-YFSEAKAGRISSVTYDGQDRHYVL-SDGGRQPNGLAFYGDRLFYADSAFDSIE 6132
+ + Y+ + K I S+ DG R ++ D R P L + +F+ D+ E
Sbjct: 1574 YSQDHIIYWVDTKLNAIESMRADGSRRKAIVRGDQLRHPVSLDLFESNMFWMTR--DTGE 1631
Query: 6133 VATINGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHINNGNCDHICIPLMFAQRT 6312
+ + + Q + + N + +K + ++ P +N C H+C+ L+
Sbjct: 1632 LVRQDKFGRGVQVV-LHRYIVNPSGLKVYHDKRYNTSLPNPCDNSTCSHLCL-LVPGGHR 1689
Query: 6313 CTC 6321
C C
Sbjct: 1690 CAC 1692
>gi|47228669|emb|CAG07401.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 2378
Score = 1119 bits (2894), Expect = 0.0
Identities = 683/2112 (32%), Positives = 1001/2112 (47%), Gaps = 123/2112 (5%)
Frame = +1
Query: 7696 IASGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAA 7875
+++ D A +D C L+FW T+ P I R++L G + VI+ I P
Sbjct: 78 MSAEDHPRAFVLDECQDLMFW------TNWNEQAPSIMRASLNGANVLVIIGSDIKTPNG 131
Query: 7876 IAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGYRAK--SLDIWDRWLYMSDPLSNG 8049
+A+D R +K+Y++D IE +YDG +R V+ L ++ +++ +D +
Sbjct: 132 LAIDHRAEKLYFSDATLDKIERCEYDGSSRYVLLKNEPVHPFGLAVYGDYIFWTDWVRRA 191
Query: 8050 VFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLC 8229
V R D A ++A+++ N C+T+NGGC LC
Sbjct: 192 VLRADNSQW--------------ASSLWANDT---------NNCEFSPCRTNNGGCQDLC 228
Query: 8230 TVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSEPAKECLPPYNFQCGDG 8409
+D +V CSC L+++ + S C F+CG+G
Sbjct: 229 LPTSD------GRVNCSCRGDRHLLED------------NTCSPLNMSCGSVDGFECGNG 270
Query: 8410 SCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHIDDCGDGS 8589
CI TCD C D SDE +YC R C + Y C N RCI C+ DDCGD S
Sbjct: 271 DCINYSLTCDGMAHCKDKSDEKQSYCANRICKKGYRRCINGRCIGHQFWCDGTDDCGDHS 330
Query: 8590 DELDCPSAVA-------------------CAEGTFPCSNGHCINQTKVCDGHNDCHD--E 8706
DEL C + + C G F C +G CI+ CD +C D +
Sbjct: 331 DELPCNTLLVLISQGLLPNWFAFLLLVTLCKPGEFQCKDGSCISNFSRCDQVVNCEDASD 390
Query: 8707 QVSDESLATCPGLPIDCRGVKVR-CPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQ- 8880
+++ +S + +G + C T +C + +CDG +DCGD +DE C +++
Sbjct: 391 EMNCQSTDCSRFFRLGVKGASFQSCERTTLCYLSSWVCDGNNDCGDFSDEKN--CPDKRK 448
Query: 8881 --CAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTN--CTDTAGKKICVGDYLFQCDN 9048
C ++ CPSGRCIP +W CD +NDC +G DETH + CT T F+C N
Sbjct: 449 LKCPVNFFACPSGRCIPMSWTCDKENDCENGADETHCDKFCTSTQ----------FECAN 498
Query: 9049 LKCISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLC 9228
+CIS ++ + C ++TC+ + F C + + C+P+ W C
Sbjct: 499 HRCISSHWVCDGSDDCGDGSDEDQK--CKSKTCSPEAFQCPGS-------HMCVPQRWKC 549
Query: 9229 DGDVTCAGGEDESTEL-CKTEKKECN-KGEFRCSNQHCIHSTWECDGDNDCLDGSDEHAN 9402
DGD C G DES + C C+ + EF C N+ CI + CD D DC DGSDE
Sbjct: 550 DGDKDCPDGADESVKAGCMYTNSTCDPENEFMCQNRQCIPKHFVCDLDVDCSDGSDESPE 609
Query: 9403 CTYSSCQPDFFQCANHKCV-PNSWKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQ 9579
C Y +C PD F+CAN +C+ W+CDG DC D SDE PKN C++ F
Sbjct: 610 CEYPTCGPDEFRCANGRCLNQKKWECDGEFDCHDHSDE--APKNPRCTSSERTCNDSAFT 667
Query: 9580 CTSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEG 9759
C +G C+++ +CDRN DC D SDE + CFI+EC ++ C Q C D+KIGYKC C G
Sbjct: 668 CLNGNCLNETLLCDRNDDCGDGSDELN-CFINECLNSKLSGCSQLCDDLKIGYKCRCHPG 726
Query: 9760 FAIDISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPE 9939
F + D K+C +V+EC CSQ+C + GS+ C CVDG+Q + E
Sbjct: 727 FQLK-RDGKTCVDVDECLTTYP-CSQRCINTHGSFHCLCVDGFQ------------PKEE 772
Query: 9940 PFFLLANKHYIRKISIDGNKYELAAQ----------------------------GFDNVV 10035
P+ + AN++Y+RK+++DG+ Y L Q G +N V
Sbjct: 773 PYLIFANRYYLRKLNLDGSNYTLIKQVRSAPAETMRWSSLLGPCARFNPFRHFQGLNNAV 832
Query: 10036 SLDIDLTEKKAYLID---QGKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDWVGR 10206
+LD E+ Y D QG + + M S+ E + R ++ +G+AVDWVG
Sbjct: 833 ALDFHYAEQMIYWTDVTTQGSM------IRRMHMNGSNMEVLHRTSLSNPDGLAVDWVGG 886
Query: 10207 KLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFFTEWSLQPYIGRIA 10386
LY ++ +I V +L+G + L+ +++P+A+ V YL++++W P+IGRI
Sbjct: 887 NLYWCDKGRDTIEVSKLNGAYRTVLVNSGLREPRALAVDVRYRYLYWSDWGDNPHIGRIG 946
Query: 10387 LDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHIPAQ 10566
+DGS + E + WPN + +D+ +DR++W DA + I F DG R +
Sbjct: 947 MDGSNRSV-----IVEEKITWPNGLTLDFINDRIYWADAREDYIEFASLDGTNRHTVLNH 1001
Query: 10567 RTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDLRIVHPMRQPAY 10746
H+ +M +F++Y+YW DW + + R K G N+T L T+ P D+ I HP RQP
Sbjct: 1002 DIPHIFAMTLFEEYIYWTDWETKSINRAHKTQGTNKTTLISTLHRPMDVHIYHPYRQPEV 1061
Query: 10747 PN-PCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTCEPNCTERQFACGGDDAKC 10923
N PC NNGGCS+LCL+ GG GY C+CP F L SDQ+TC NCT QF C D KC
Sbjct: 1062 LNHPCQTNNGGCSNLCLLSPGG-GYKCACPTNFYLASDQRTCMSNCTASQFVCKND--KC 1118
Query: 10924 IPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXX 11103
IP W CD E DC D SDEP + C + C G+FQC CT P I
Sbjct: 1119 IPFWWKCDTEDDCGDRSDEPAD--CPEFKCRPGQFQCGTGICTNPAYICDGDNDCQDNSD 1176
Query: 11104 EQNCD-KACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEADTLCMSAERNCTAEEFRC 11280
E NCD C P FKC+ RCIP F DE D E C +F+C
Sbjct: 1177 EANCDIHVCLPSQFKCSHPSRCIPGIFRCNGQDNCGDGEDEKD----CPEVTCAPTQFQC 1232
Query: 11281 N-NNKCIAKAWRXXXXXXXXXXXXETPECAQIECKKGWTRCSSSYRCIPNWAFCNGQDDC 11457
+CI + W E C Q+ C RC S RCIP C+G+DDC
Sbjct: 1233 AITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDC 1292
Query: 11458 RDNSDEDKQRCP--TCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRP 11631
D SDE K+ C TC+ +FRC + +C+P RW CD +NDCGDNSDE C R
Sbjct: 1293 GDASDEPKEECAERTCEPY-QFRC-KNNRCVPGRWQCDYDNDCGDNSDE--DKC--MPRQ 1346
Query: 11632 CSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQCDDGTCIAEHKWCD 11811
CSESEF C +G+CI G CDG C+DG DE C L +C H QC++G CI CD
Sbjct: 1347 CSESEFACTNGRCIAGRWKCDGDHDCADGSDEHGCDL-KCDTDHFQCNNGHCIPIRWRCD 1405
Query: 11812 RKKDCPNAADELHCEDVSRRTCSPFEFECANSVCIPRKFMXXXXXXXXXXSDETSSECRS 11991
DC + +DE +C + R C EF+C N++C P + SDE +CR
Sbjct: 1406 ADPDCLDGSDEENCGSATERHCPADEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEQCRK 1465
Query: 11992 AQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPND-------------------FSDEHLS 12114
QC P FRC + R+CL + + C+G N+CG N F D +
Sbjct: 1466 FQCPPTRAFRCQNDRVCLQVSKRCDGVNNCGDNSDELNCRTCWTPSCSYEICAFLDCKRN 1525
Query: 12115 MCSSFSE----YGDCSSDQFKCANGKCVNGTVACDRKDDCGD-ASDEIGCSKHGGKTSCE 12279
+C + +E C D+F CAN +C++ T+ C+ +DC D SDEIGC C
Sbjct: 1526 ICCASTETPPAVPTCEKDEFLCANHRCISSTLRCNLFNDCEDFGSDEIGCKTDTKLNDCR 1585
Query: 12280 A---FGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTK 12450
+ +G H T+ D F C C+ GF+ + C D +EC C+ C NTK
Sbjct: 1586 SNRTHCGDGDEAHCVTNGTDSF-CSCKPGFQ--KIGHRTCGDKNECLQFGVCSHSCNNTK 1642
Query: 12451 GSYLCRCHEDYENNVVVGSMTGKDCRAK--GDAANVMIGADDSLVQLSLHGSGTNRHXXX 12624
GSY C CH+ + + C+A + ++ ADD+ ++ G R+
Sbjct: 1643 GSYKCSCHKYF-------TRISDTCKADNINSSRQILYIADDNEIRSLDPGMPDWRYEQT 1695
Query: 12625 XXXXXXXXXXXXXXXPRKELMYWIDGSERTIYR------SAIANGNQSH------EGQKL 12768
+ ++W + I S A + SH EG+
Sbjct: 1696 FQGDASVRIDAMDVHVKTNRIFWTNWHTGRISTYELQGPSLSATSSNSHRHRRQSEGRVT 1755
Query: 12769 DVDFAAMGVVPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCL 12948
D+ + +P IAVD+ GNL+ ++ I V
Sbjct: 1756 DLQIKEL-KMPRGIAVDWVAGNLYWTDSGRDV-----------------------IEVAQ 1791
Query: 12949 PDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFS 13128
G+ K +++G + +P A++ P G + ++D G H KIE A MDGT RQ +V + +
Sbjct: 1792 MSGQNCKTLISGMIDEPYAIVVNPQRGTMYWADWGNHPKIETAAMDGTLRQTLVHENIQW 1851
Query: 13129 PTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVV----HDRHIPYAVDVFENHIYW 13296
PT +A+D R+YW D K + +V +DGS+ V ++ P+++D+FE++IY
Sbjct: 1852 PTGLAVDY-FNERLYWADAKLSVIGSVRLDGSDPVISVSGLKNNLLHPFSIDIFEDYIYG 1910
Query: 13297 LSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVS 13476
++ + ++ +KFG+G++ L + + + + +Y K + T + C+R +C LC+
Sbjct: 1911 VTYINNIVFRVNKFGKGKMENLTTGINHASDIVLHHRY-KQPEMT-NPCDRKKCEWLCLL 1968
Query: 13477 LPSTGFACLCPDGIVPQLDGSCATQHVEAL------TMPKQCKCTNGGKCRLD----GSC 13626
PS G C CP+ V +G+C + V + P +C NGG C L+ C
Sbjct: 1969 SPS-GPVCTCPNKYVAD-NGTCVEKPVPTQSPFSPPSEPCDIQCLNGGSCFLNARQVAKC 2026
Query: 13627 ECTSDFEGDQCE 13662
C + G++CE
Sbjct: 2027 RCQPSYIGERCE 2038
Score = 446 bits (1147), Expect = e-123
Identities = 373/1297 (28%), Positives = 535/1297 (40%), Gaps = 178/1297 (13%)
Frame = +1
Query: 7570 HAKEIRHISDMKLDWLTQKIYFT--TGRGGKVMAIDTAGE-----HLSTIASGDWTYALA 7728
H + + + + + Q IY+T T +G + + G H +++++ D LA
Sbjct: 824 HFQGLNNAVALDFHYAEQMIYWTDVTTQGSMIRRMHMNGSNMEVLHRTSLSNPD---GLA 880
Query: 7729 IDPCSGLLFWSDSG------------YKT---SGGLYEPR-------------------- 7803
+D G L+W D G Y+T + GL EPR
Sbjct: 881 VDWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVNSGLREPRALAVDVRYRYLYWSDWGDNP 940
Query: 7804 -IERSNLAGGSRKVIVSESISLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIAS 7980
I R + G +R VIV E I+ P + +DF N +IYWAD IE A DG NR + +
Sbjct: 941 HIGRIGMDGSNRSVIVEEKITWPNGLTLDFINDRIYWADAREDYIEFASLDGTNRHTVLN 1000
Query: 7981 G--YRAKSLDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESDVR 8154
++ +++ ++Y +D + + R K G+ ++S P + ++
Sbjct: 1001 HDIPHIFAMTLFEEYIYWTDWETKSINRAHKTQGTNKTTLISTLHRPMDVHIYHPYRQPE 1060
Query: 8155 TRNQVCNALTSQLCKTDNGGCDQLCTV---------VADDIGLAASKVQCSCNDT-YELV 8304
N C+T+NGGC LC + + LA+ + C N T + V
Sbjct: 1061 VLNHP--------CQTNNGGCSNLCLLSPGGGYKCACPTNFYLASDQRTCMSNCTASQFV 1112
Query: 8305 QEPGKDYP--TQCVLR---GSNSEPAKEC----LPPYNFQCGDGSCILLGATCDSKPDCA 8457
+ K P +C G S+ +C P FQCG G C CD DC
Sbjct: 1113 CKNDKCIPFWWKCDTEDDCGDRSDEPADCPEFKCRPGQFQCGTGICTNPAYICDGDNDCQ 1172
Query: 8458 DASDENPNYCNTRSC-PEDYNLCTNRRCIDSAKKCNHIDDCGDGSDELDCPSAVACAEGT 8634
D SDE C+ C P + RCI +CN D+CGDG DE DCP V CA
Sbjct: 1173 DNSDE--ANCDIHVCLPSQFKCSHPSRCIPGIFRCNGQDNCGDGEDEKDCPE-VTCAPTQ 1229
Query: 8635 FPCS-NGHCINQTKVCDGHNDCHDEQVSDESLATCPGLPIDCRGVKVRCPNTNICIQPAD 8811
F C+ CI + VCD NDC D SDE A C + C + RC ++ CI
Sbjct: 1230 FQCAITKRCIPRVWVCDRDNDCVDG--SDEP-ANC--TQMTCGVDEFRCKDSGRCIPARW 1284
Query: 8812 LCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNC 8991
CDG DDCGD +DE + C + C + RC + RC+P WQCD DNDC D DE
Sbjct: 1285 KCDGEDDCGDASDEPKEECAERTCEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDED---- 1340
Query: 8992 TDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCT 9171
KC+ R C++ EF CT
Sbjct: 1341 --------------------KCMPR-------------------------QCSESEFACT 1355
Query: 9172 SNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECNKGEFRCSNQHCIHSTW 9351
+ CI W CDGD CA G DE C +C+ F+C+N HCI W
Sbjct: 1356 NG--------RCIAGRWKCDGDHDCADGSDEHG--CDL---KCDTDHFQCNNGHCIPIRW 1402
Query: 9352 ECDGDNDCLDGSDEHANC---TYSSCQPDFFQCANHKCVPNSWKCDGNDDCEDGSDE--K 9516
CD D DCLDGSDE NC T C D FQC N C P +WKCDG DDC D SDE +
Sbjct: 1403 RCDADPDCLDGSDEE-NCGSATERHCPADEFQCNNTLCKPLAWKCDGEDDCGDNSDENPE 1461
Query: 9517 DCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESS--LCFIDECSL- 9687
C K +A +C N + C+ +K CD +C D SDE + C+ CS
Sbjct: 1462 QCRKFQCPPTRAFRCQNDRV------CLQVSKRCDGVNNCGDNSDELNCRTCWTPSCSYE 1515
Query: 9688 -------------------AEKPLCEQ--------KCMDMKIGYKCDCF---EGFAIDIS 9777
P CE+ +C+ + +C+ F E F D
Sbjct: 1516 ICAFLDCKRNICCASTETPPAVPTCEKDEFLCANHRCISSTL--RCNLFNDCEDFGSDEI 1573
Query: 9778 DQKSCHNVNECYEGISGC------------------------------------------ 9831
K+ +N+C + C
Sbjct: 1574 GCKTDTKLNDCRSNRTHCGDGDEAHCVTNGTDSFCSCKPGFQKIGHRTCGDKNECLQFGV 1633
Query: 9832 -SQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFL-LANKHYIRKI--SIDGNK 9999
S C++ GSYKC C + SD +CK + L +A+ + IR + + +
Sbjct: 1634 CSHSCNNTKGSYKCSCHKYFTRISD--TCKADNINSSRQILYIADDNEIRSLDPGMPDWR 1691
Query: 10000 YELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRH------ 10161
YE QG D V +D K I R+ E+ P S + H
Sbjct: 1692 YEQTFQG-DASVRIDAMDVHVKTNRIFWTNWHTGRISTYELQGPSLSATSSNSHRHRRQS 1750
Query: 10162 ----------NVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKA 10311
+ GIAVDWV LY + I V ++ G+ CKTLI I +P A
Sbjct: 1751 EGRVTDLQIKELKMPRGIAVDWVAGNLYWTDSGRDVIEVAQMSGQNCKTLISGMIDEPYA 1810
Query: 10312 IVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLF 10491
IVV+P +G +++ +W P I A+DG+ L ++ WP +A+DYF++RL+
Sbjct: 1811 IVVNPQRGTMYWADWGNHPKIETAAMDGTLRQ-----TLVHENIQWPTGLAVDYFNERLY 1865
Query: 10492 WGDAHLNEIGFMDFDGNGRRHIPAQRTS-------HVSSMVVFDDYLYWADWNLREVLRC 10650
W DA L+ IG + DG+ P S H S+ +F+DY+Y + V R
Sbjct: 1866 WADAKLSVIGSVRLDGSD----PVISVSGLKNNLLHPFSIDIFEDYIYGVTYINNIVFRV 1921
Query: 10651 DKW-TGKNETILKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCS 10827
+K+ GK E L + +D+ + H +QP NPC + C LCL+ +G C+
Sbjct: 1922 NKFGKGKMEN-LTTGINHASDIVLHHRYKQPEMTNPC--DRKKCEWLCLLSP--SGPVCT 1976
Query: 10828 CPDQFVLLSDQKTC--EPNCTERQFACGGD--DAKCI 10926
CP+++V +D TC +P T+ F+ + D +C+
Sbjct: 1977 CPNKYV--ADNGTCVEKPVPTQSPFSPPSEPCDIQCL 2011
Score = 404 bits (1039), Expect = e-110
Identities = 369/1369 (26%), Positives = 530/1369 (37%), Gaps = 248/1369 (18%)
Frame = +1
Query: 2011 NPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLV-NGKRCIDSID------------- 2148
N C N+ G L D +GYKC C G +L +GK C+D +
Sbjct: 698 NECLNSKLSGCSQLCDD---LKIGYKCRCHPGFQLKRDGKTCVDVDECLTTYPCSQRCIN 754
Query: 2149 -------------------YLLFSSNKIVRGIFPEINEKALAEAVLP-----------IS 2238
YL+F++ +R + + + L + V +
Sbjct: 755 THGSFHCLCVDGFQPKEEPYLIFANRYYLRKLNLDGSNYTLIKQVRSAPAETMRWSSLLG 814
Query: 2239 PISQRRIGMYFEVECDVHGNSFFYADIM---------DNTIYRIRPDGEGAAPVLVTHND 2391
P ++ +F+ + F YA+ M + I R+ +G + T
Sbjct: 815 PCARFNPFRHFQGLNNAVALDFHYAEQMIYWTDVTTQGSMIRRMHMNGSNMEVLHRTSLS 874
Query: 2392 GLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITE-LRDPVSVVVHP 2568
++ DW+ LY+ D R+++EV K+ R L+ LR+P ++ V
Sbjct: 875 NPDGLAVDWVGGNLYWCDKGRDTIEVSKLNGA--------YRTVLVNSGLREPRALAVDV 926
Query: 2569 WKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTIS 2748
L++++ I R +DG N VI + P+ + +DF +R+ W D I
Sbjct: 927 RYRYLYWSDWGDNPHIGRIGMDGSNRSVIVEEKITWPNGLTLDFINDRIYWADAREDYIE 986
Query: 2749 CMDFDGKNV-VKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGAD 2925
DG N L+ D P A+T+ EYIY+ SI R HK G +
Sbjct: 987 FASLDGTNRHTVLNHDIPHIFAMTLFEEYIYWTDWETKSINRAHKTQGTNKTTLI----- 1041
Query: 2926 ERSIFSLKACSHQNQPIPD-DSREHPCRASQ--CTQLCFATPSESHPNELEAKCACRQGF 3096
S H P + HPC+ + C+ LC +P + KCAC F
Sbjct: 1042 --STLHRPMDVHIYHPYRQPEVLNHPCQTNNGGCSNLCLLSPGGGY------KCACPTNF 1093
Query: 3097 MINKENNHSCQKDPAEKIEQLCSSNST--QFQCKNGRCIPKEWKCD-------------- 3228
+ + ++ C SN T QF CKN +CIP WKCD
Sbjct: 1094 YLASD-------------QRTCMSNCTASQFVCKNDKCIPFWWKCDTEDDCGDRSDEPAD 1140
Query: 3229 --------------------------GENDCLDESDEID-------EKGDKCFH------ 3291
G+NDC D SDE + KC H
Sbjct: 1141 CPEFKCRPGQFQCGTGICTNPAYICDGDNDCQDNSDEANCDIHVCLPSQFKCSHPSRCIP 1200
Query: 3292 ---------------------ETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVK 3408
E CA +C TK+CIP
Sbjct: 1201 GIFRCNGQDNCGDGEDEKDCPEVTCAPTQFQCAITKRCIPRVWVCDRDND---------- 1250
Query: 3409 YCKDGQ-------KPVCAAKKFQC-DNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNATCA 3564
C DG + C +F+C D+ RCIP +WK E E C TC
Sbjct: 1251 -CVDGSDEPANCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDASDEPKEECAERTCE 1309
Query: 3565 ANQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQCVPLRNHX 3744
QF C N RC+P W CD DNDC D +DEDK C P QCS +F C NGR C+ R
Sbjct: 1310 PYQFRCKNNRCVPGRWQCDYDNDCGDNSDEDK--CMPRQCSESEFACTNGR-CIAGRWKC 1366
Query: 3745 XXXXXXXXXXXXXXXAVTAESCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCT 3924
+ C D F+C ++G CIP W+ SDE G
Sbjct: 1367 DGDHDCADGSDEHGCDL---KCDTDHFQC-NNGHCIPIRWRCDADPDCLDGSDEENCGSA 1422
Query: 3925 SGRQCSSDQFKCGNGRCILNNWLCDGENDCGDGSDE------------------------ 4032
+ R C +D+F+C N C W CDGE+DCGD SDE
Sbjct: 1423 TERHCPADEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEQCRKFQCPPTRAFRCQNDRVC 1482
Query: 4033 ----------------SSERGCKTSMNARKCPFEHVA---------------------CE 4101
S E C+T C +E A CE
Sbjct: 1483 LQVSKRCDGVNNCGDNSDELNCRTCWTP-SCSYEICAFLDCKRNICCASTETPPAVPTCE 1541
Query: 4102 NDQ-----ETCIPLHQLCDGKTHCPG-GTDEGGRCARDL----CSADRAGCSF--KCHNS 4245
D+ CI C+ C G+DE G C D C ++R C + H
Sbjct: 1542 KDEFLCANHRCISSTLRCNLFNDCEDFGSDEIG-CKTDTKLNDCRSNRTHCGDGDEAHCV 1600
Query: 4246 PNGP--ICSCPFGEQLVNKTKCEPENECLDSSSCSQRCKDEKHGFTCSCDEGYELDVDKR 4419
NG CSC G Q + C +NECL CS C + K + CSC + + D
Sbjct: 1601 TNGTDSFCSCKPGFQKIGHRTCGDKNECLQFGVCSHSCNNTKGSYKCSCHKYFTRISD-- 1658
Query: 4420 TCKVADNVKDTR--IYVSNRNRIYYSDHKLDNWHTFGAIVENAIALAWDSL-----TDRI 4578
TCK ADN+ +R +Y+++ N I D + +W + + ++ D++ T+RI
Sbjct: 1659 TCK-ADNINSSRQILYIADDNEIRSLDPGMPDWR-YEQTFQGDASVRIDAMDVHVKTNRI 1716
Query: 4579 YWSDIREKKI---------LSANRNGTNATVFIADG---------LDITEGIALDWVGRN 4704
+W++ +I LSA + ++ ++G L + GIA+DWV N
Sbjct: 1717 FWTNWHTGRISTYELQGPSLSATSSNSHRHRRQSEGRVTDLQIKELKMPRGIAVDWVAGN 1776
Query: 4705 LYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQNPCIERAS 4884
LYW DS + IEVA + +TL+ + +P I V+P++G M+W DWG +P IE A+
Sbjct: 1777 LYWTDSGRDVIEVAQMSGQNCKTLISGM-IDEPYAIVVNPQRGTMYWADWGNHPKIETAA 1835
Query: 4885 MDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRT-QVLASSKFV 5061
MDGT RQ +V I WP +A+DY +R+Y+AD+KL I V DGS V +
Sbjct: 1836 MDGTLRQTLVHENIQWPTGLAVDYFNERLYWADAKLSVIGSVRLDGSDPVISVSGLKNNL 1895
Query: 5062 QHPHALAIFEDMMY---YSDRRLQKLQVY--PKYPNGTTSEYPSHTFSKALGVVAVHPVL 5226
HP ++ IFED +Y Y + + ++ + K N TT + A +V H
Sbjct: 1896 LHPFSIDIFEDYIYGVTYINNIVFRVNKFGKGKMENLTTG------INHASDIVLHHRYK 1949
Query: 5227 QPVIKNNPCSTNPCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKP 5373
QP + NPC C LCLL+ C CP K A C++ P
Sbjct: 1950 QPEM-TNPCDRKKCEWLCLLSPSGP-VCTCP--NKYVADNGTCVEKPVP 1994
Score = 365 bits (937), Expect = 2e-98
Identities = 239/767 (31%), Positives = 351/767 (45%), Gaps = 38/767 (4%)
Frame = +1
Query: 3178 QFQCKNGRCIPKEWKCDGENDCLDESDEIDEKGDKC---FHETECAENTIKCRNTKKCIP 3348
+FQCK+G CI +CD +C D SDE++ + C F + C T C
Sbjct: 364 EFQCKDGSCISNFSRCDQVVNCEDASDEMNCQSTDCSRFFRLGVKGASFQSCERTTLCYL 423
Query: 3349 AQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXX 3528
+ K C D +K C F C + RCIP W
Sbjct: 424 SSWVCDGNNDCGDFSDE--KNCPDKRKLKCPVNFFACPSGRCIPMSW-----------TC 470
Query: 3529 EKLEMCGNAT--------CAANQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQC 3684
+K C N C + QF CAN RCI +W+CDG +DC DG+DED ++C C
Sbjct: 471 DKENDCENGADETHCDKFCTSTQFECANHRCISSHWVCDGSDDCGDGSDED-QKCKSKTC 529
Query: 3685 SALQFRCANGRQCVPLR---NHXXXXXXXXXXXXXXXXAVTAESCTPDQFKCVSSGLCIP 3855
S F+C CVP R + T +C P+ + CIP
Sbjct: 530 SPEAFQCPGSHMCVPQRWKCDGDKDCPDGADESVKAGCMYTNSTCDPENEFMCQNRQCIP 589
Query: 3856 ASWKXXXXXXXXXXSDE-PKFGCTSGRQCSSDQFKCGNGRCI-LNNWLCDGENDCGDGSD 4029
+ SDE P+ + C D+F+C NGRC+ W CDGE DC D SD
Sbjct: 590 KHFVCDLDVDCSDGSDESPECEYPT---CGPDEFRCANGRCLNQKKWECDGEFDCHDHSD 646
Query: 4030 ESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGGRCARDLCSA 4209
E+ + TS + R C C N C+ LCD C G+DE + ++
Sbjct: 647 EAPKNPRCTS-SERTCNDSAFTCLNG--NCLNETLLCDRNDDCGDGSDELNCFINECLNS 703
Query: 4210 DRAGCSFKCHNSPNGPICSCPFGEQLVNKTK-CEPENECLDSSSCSQRCKDEKHGFTCSC 4386
+GCS C + G C C G QL K C +ECL + CSQRC + F C C
Sbjct: 704 KLSGCSQLCDDLKIGYKCRCHPGFQLKRDGKTCVDVDECLTTYPCSQRCINTHGSFHCLC 763
Query: 4387 DEGYE-----------------LDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWH 4515
+G++ L++D + V+ + + + + +
Sbjct: 764 VDGFQPKEEPYLIFANRYYLRKLNLDGSNYTLIKQVRSAPAETMRWSSLLGPCARFNPFR 823
Query: 4516 TFGAIVENAIALAWDSLTDRIYWSDI--REKKILSANRNGTNATVFIADGLDITEGIALD 4689
F + NA+AL + IYW+D+ + I + NG+N V L +G+A+D
Sbjct: 824 HFQGL-NNAVALDFHYAEQMIYWTDVTTQGSMIRRMHMNGSNMEVLHRTSLSNPDGLAVD 882
Query: 4690 WVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQNPC 4869
WVG NLYW D +TIEV+ L + RT+LV+ + +PR +AVD R ++W+DWG NP
Sbjct: 883 WVGGNLYWCDKGRDTIEVSKL-NGAYRTVLVNSGLREPRALAVDVRYRYLYWSDWGDNPH 941
Query: 4870 IERASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLAS 5049
I R MDG++R +IV+ KI WPN + LD+ DR+Y+AD++ D+I+F + DG+ R VL
Sbjct: 942 IGRIGMDGSNRSVIVEEKITWPNGLTLDFINDRIYWADAREDYIEFASLDGTNRHTVL-- 999
Query: 5050 SKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQ 5229
+ + H A+ +FE+ +Y++D + + K GT T + + V HP Q
Sbjct: 1000 NHDIPHIFAMTLFEEYIYWTDWETKSINRAHK-TQGTNKTTLISTLHRPMDVHIYHPYRQ 1058
Query: 5230 PVIKNNPCSTN--PCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDD 5364
P + N+PC TN CS+LCLL+ + C CP L + + C+ +
Sbjct: 1059 PEVLNHPCQTNNGGCSNLCLLSPGGGYKCACPTNFYLASDQRTCMSN 1105
Score = 308 bits (790), Expect = 2e-81
Identities = 216/689 (31%), Positives = 308/689 (44%), Gaps = 31/689 (4%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAE 336
C N F C G+CI W C S Q++C + CI+
Sbjct: 451 CPVNFFACPSGRCIPMSWTCDKENDCENGADETHCDK-FCTSTQFECANHR-----CISS 504
Query: 337 YQRCDNITDCADGSDE-KDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDE 513
+ CD DC DGSDE + C + T CS + F C C KCDG DC D +DE
Sbjct: 505 HWVCDGSDDCGDGSDEDQKCKSKT--CSPE-AFQCPGSHMCVPQRWKCDGDKDCPDGADE 561
Query: 514 --KDSCSRNHTACF-QYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEF 684
K C ++ C + +F C ++ QCI K +VCD DC+DGSDE CE+ C +EF
Sbjct: 562 SVKAGCMYTNSTCDPENEFMCQNR-QCIPKHFVCDLDVDCSDGSDESPECEYPTCGPDEF 620
Query: 685 QCKNKRC-QPRKFRCDYYDDCGDNSDE----DEC--GEYRCPPGKWNCPGTGHCIDQLKL 843
+C N RC +K+ CD DC D+SDE C E C + C G+C+++ L
Sbjct: 621 RCANGRCLNQKKWECDGEFDCHDHSDEAPKNPRCTSSERTCNDSAFTCL-NGNCLNETLL 679
Query: 844 CDGSKDCADGADEQQCSQNLCPS---LGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSD 1014
CD + DC DG+DE C N C + GC C G +C C G++L R +TC D
Sbjct: 680 CDRNDDCGDGSDELNCFINECLNSKLSGCSQLCDDLKIGYKCRCHPGFQL-KRDGKTCVD 738
Query: 1015 INECAEFGYCDQLCANHRPGFTCSCLGDCFTLQME--------HGPGKDNLTMRGYCVSN 1170
++EC C Q C N F C C+ D F + E + K NL Y +
Sbjct: 739 VDECLTTYPCSQRCINTHGSFHCLCV-DGFQPKEEPYLIFANRYYLRKLNLDGSNYTLIK 797
Query: 1171 NADKMKLFVARREGLY----RLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAH 1338
R L R NP + + + +DF Y ++ I+WTD
Sbjct: 798 QVRSAPAETMRWSSLLGPCARFNPFRHFQGLNNAVA------LDFHYAEQMIYWTDVTTQ 851
Query: 1339 SAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRT 1518
+ + G S ++ L SL P LAVDW+ LY + G I+VS +G RT
Sbjct: 852 GSMIRRMHMNG--SNMEVLHRTSLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLNGAYRT 909
Query: 1519 VLLADGLTLPLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVD 1689
VL+ GL P +A+D ++++ + + MDG+NR +V +G+ +D
Sbjct: 910 VLVNSGLREPRALAVDVRYRYLYWSDWGDNPHIGRIGMDGSNRSVIVEEKITWPNGLTLD 969
Query: 1690 ITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVI 1869
R+YW D + D +E G +R V + +PH F + LF++Y+YWTDW +
Sbjct: 970 FINDRIYWADAREDYIEFASLDGTNRHTVLN--HDIPHIFAMTLFEEYIYWTDWETKSIN 1027
Query: 1870 QVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPC--TNADCEGM 2043
+ K K +T + PM + YHP QP + +PC N C +
Sbjct: 1028 RAHKTQGTNKTTLISTLHR--PMDVHIYHPYRQP---------EVLNHPCQTNNGGCSNL 1076
Query: 2044 CILSKDNGGFGVGYKCACPIGQKLVNGKR 2130
C+LS G GYKCACP L + +R
Sbjct: 1077 CLLSP-----GGGYKCACPTNFYLASDQR 1100
Score = 272 bits (696), Expect = 2e-70
Identities = 207/730 (28%), Positives = 308/730 (41%), Gaps = 65/730 (8%)
Frame = +1
Query: 145 ASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVS 324
A C FRC + +C+ W C ++ C +
Sbjct: 1304 AERTCEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDEDKCMPRQCSESEFACT-----NGR 1358
Query: 325 CIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDL 504
CIA +CD DCADGSDE C + C + + F C +G C + +CD DC D
Sbjct: 1359 CIAGRWKCDGDHDCADGSDEHGCD---LKCDTDH-FQCNNGH-CIPIRWRCDADPDCLDG 1413
Query: 505 SDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDE-PDTCEFKKCTANE 681
SDE++ S C +F+C + T C +W CDG DC D SDE P+ C +C
Sbjct: 1414 SDEENCGSATERHCPADEFQC-NNTLCKPLAWKCDGEDDCGDNSDENPEQCRKFQCPPTR 1472
Query: 682 -FQCKNKR-CQPRKFRCDYYDDCGDNSDEDEC------------------------GEYR 783
F+C+N R C RCD ++CGDNSDE C
Sbjct: 1473 AFRCQNDRVCLQVSKRCDGVNNCGDNSDELNCRTCWTPSCSYEICAFLDCKRNICCASTE 1532
Query: 784 CPPGKWNCP------GTGHCIDQLKLCDGSKDCAD-GADEQQCSQ----NLCPSL----- 915
PP C CI C+ DC D G+DE C N C S
Sbjct: 1533 TPPAVPTCEKDEFLCANHRCISSTLRCNLFNDCEDFGSDEIGCKTDTKLNDCRSNRTHCG 1592
Query: 916 -GCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCL 1092
G +A C + C+C G++ HRTC D NEC +FG C C N + + CSC
Sbjct: 1593 DGDEAHCVTNGTDSFCSCKPGFQKIG--HRTCGDKNECLQFGVCSHSCNNTKGSYKCSC- 1649
Query: 1093 GDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKLASGE 1272
+ ++ DN+ N+ + L++A + L+P PD ++ G+
Sbjct: 1650 -HKYFTRISDTCKADNI---------NSSRQILYIADDNEIRSLDPGMPDWRYEQTFQGD 1699
Query: 1273 F---IYGIDFDYGDRKIFWTD--------------RLAHSAFSADVDDEGEISQIKKLSL 1401
I +D +IFWT+ L+ ++ ++ ++ L +
Sbjct: 1700 ASVRIDAMDVHVKTNRIFWTNWHTGRISTYELQGPSLSATSSNSHRHRRQSEGRVTDLQI 1759
Query: 1402 KSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGE 1581
K L PR +AVDW+ LY +SG I+V+ G+ L++ + P I ++P RG
Sbjct: 1760 KELKMPRGIAVDWVAGNLYWTDSGRDVIEVAQMSGQNCKTLISGMIDEPYAIVVNPQRGT 1819
Query: 1582 MFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDY 1752
M++ N K+E AAMDGT R+TLV+ + +G+ VD +R+YW D K+ + S+
Sbjct: 1820 MYWADWGNHPKIETAAMDGTLRQTLVHENIQWPTGLAVDYFNERLYWADAKLSVIGSVRL 1879
Query: 1753 QGNDRRIVAQGM-NVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNV 1929
G+D I G+ N + HPF + +F+ Y+Y + V +V KFG + N+
Sbjct: 1880 DGSDPVISVSGLKNNLLHPFSIDIFEDYIYGVTYINNIVFRVNKFGKGKMENLTTGINHA 1939
Query: 1930 FPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQ 2109
I +H QP ++ NPC CE +C+LS G C CP
Sbjct: 1940 --SDIVLHHRYKQP----------EMTNPCDRKKCEWLCLLSPS------GPVCTCPNKY 1981
Query: 2110 KLVNGKRCID 2139
NG C++
Sbjct: 1982 VADNG-TCVE 1990
Score = 177 bits (448), Expect = 9e-42
Identities = 92/246 (37%), Positives = 119/246 (47%), Gaps = 1/246 (0%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAE 336
C F+C G C + C Q++C H CI
Sbjct: 1146 CRPGQFQCGTGICTNPAYICDGDNDCQDNSDEANCDIHVCLPSQFKCS----HPSRCIPG 1201
Query: 337 YQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEK 516
RC+ +C DG DEKDCP T + F CA ++C CD DC D SDE
Sbjct: 1202 IFRCNGQDNCGDGEDEKDCPEVTC---APTQFQCAITKRCIPRVWVCDRDNDCVDGSDEP 1258
Query: 517 DSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEP-DTCEFKKCTANEFQCK 693
+C++ C +FRC D +CI W CDG DC D SDEP + C + C +F+CK
Sbjct: 1259 ANCTQ--MTCGVDEFRCKDSGRCIPARWKCDGEDDCGDASDEPKEECAERTCEPYQFRCK 1316
Query: 694 NKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADG 873
N RC P +++CDY +DCGDNSDED+C +C ++ C G CI CDG DCADG
Sbjct: 1317 NNRCVPGRWQCDYDNDCGDNSDEDKCMPRQCSESEFACT-NGRCIAGRWKCDGDHDCADG 1375
Query: 874 ADEQQC 891
+DE C
Sbjct: 1376 SDEHGC 1381
Score = 159 bits (403), Expect = 1e-36
Identities = 84/212 (39%), Positives = 108/212 (50%), Gaps = 9/212 (4%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCS--------SQNV 429
CK ++QC SCI+ + RCD + +C D SDE +C + DCS +
Sbjct: 360 CKPGEFQCK-----DGSCISNFSRCDQVVNCEDASDEMNC--QSTDCSRFFRLGVKGASF 412
Query: 430 FMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCD 609
C C+ S CDG DC D SDEK+ + C F C +CI SW CD
Sbjct: 413 QSCERTTLCYLSSWVCDGNNDCGDFSDEKNCPDKRKLKCPVNFFAC-PSGRCIPMSWTCD 471
Query: 610 GSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDE-CGEYRC 786
DC +G+DE +F CT+ +F+C N RC + CD DDCGD SDED+ C C
Sbjct: 472 KENDCENGADETHCDKF--CTSTQFECANHRCISSHWVCDGSDDCGDGSDEDQKCKSKTC 529
Query: 787 PPGKWNCPGTGHCIDQLKLCDGSKDCADGADE 882
P + CPG+ C+ Q CDG KDC DGADE
Sbjct: 530 SPEAFQCPGSHMCVPQRWKCDGDKDCPDGADE 561
Score = 142 bits (358), Expect = 2e-31
Identities = 95/305 (31%), Positives = 127/305 (41%), Gaps = 44/305 (14%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDE-KDCPA----------------- 399
C + Q+ C + CI + +CD DC D SDE DCP
Sbjct: 1106 CTASQFVCK-----NDKCIPFWWKCDTEDDCGDRSDEPADCPEFKCRPGQFQCGTGICTN 1160
Query: 400 ------STVDCSSQ-------------NVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDS 522
DC + F C+ +C +C+G+ +C D DEKD
Sbjct: 1161 PAYICDGDNDCQDNSDEANCDIHVCLPSQFKCSHPSRCIPGIFRCNGQDNCGDGEDEKDC 1220
Query: 523 CSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNK- 699
C QF+CA +CI + WVCD DC DGSDEP C C +EF+CK+
Sbjct: 1221 ---PEVTCAPTQFQCAITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDEFRCKDSG 1277
Query: 700 RCQPRKFRCDYYDDCGDNSDE--DECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADG 873
RC P +++CD DDCGD SDE +EC E C P ++ C C+ CD DC D
Sbjct: 1278 RCIPARWKCDGEDDCGDASDEPKEECAERTCEPYQFRCK-NNRCVPGRWQCDYDNDCGDN 1336
Query: 874 ADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECA----EFGY 1041
+DE +C C E C +G + R+ C ++CA E G
Sbjct: 1337 SDEDKCMPRQCSE-------------SEFACTNGRCIAGRW--KCDGDHDCADGSDEHG- 1380
Query: 1042 CDQLC 1056
CD C
Sbjct: 1381 CDLKC 1385
Score = 127 bits (318), Expect = 1e-26
Identities = 87/265 (32%), Positives = 125/265 (46%), Gaps = 12/265 (4%)
Frame = +1
Query: 343 RCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDS 522
+C T+ SD++ C ++ C++ F+C + + C KCD + DC D SDE
Sbjct: 1086 KCACPTNFYLASDQRTCMSN---CTASQ-FVCKNDK-CIPFWWKCDTEDDCGDRSDEPAD 1140
Query: 523 CSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKN-K 699
C C QF+C C +++CDG DC D SDE + C+ C ++F+C +
Sbjct: 1141 CPE--FKCRPGQFQCGTGI-CTNPAYICDGDNDCQDNSDEAN-CDIHVCLPSQFKCSHPS 1196
Query: 700 RCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGAD 879
RC P FRC+ D+CGD DE +C E C P ++ C T CI ++ +CD DC DG+D
Sbjct: 1197 RCIPGIFRCNGQDNCGDGEDEKDCPEVTCAPTQFQCAITKRCIPRVWVCDRDNDCVDGSD 1256
Query: 880 EQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDIN-----ECAEFGYC 1044
E C + C G C P+ +K D C D + ECAE C
Sbjct: 1257 EPA----NCTQMTCGVDEFRCKDSGRC-IPARWKCDG--EDDCGDASDEPKEECAE-RTC 1308
Query: 1045 DQL---CANHR--PG-FTCSCLGDC 1101
+ C N+R PG + C DC
Sbjct: 1309 EPYQFRCKNNRCVPGRWQCDYDNDC 1333
Score = 126 bits (317), Expect = 1e-26
Identities = 89/265 (33%), Positives = 133/265 (49%), Gaps = 5/265 (1%)
Frame = +1
Query: 6481 VDYDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINYNMYFI 6660
+D+ Y + IY + + I + S+ + R S+ + LA+DW+ N+Y+
Sbjct: 834 LDFHYAEQMIYWTDVTTQGSMIRRMHMNGSNMEVLHRTSLSNPD--GLAVDWVGGNLYWC 891
Query: 6661 NHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQRSFLDG 6840
D R IEVSKL+G YR +L+ + P ++AVD RYLYW+D G P I R +DG
Sbjct: 892 --DKGRDTIEVSKLNGAYRTVLVNSGLREPRALAVDVRYRYLYWSDWGDNPHIGRIGMDG 949
Query: 6841 SRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPE--LVRSDIASAAG 7014
S R VIV I P L +D + IYW+DA+ D I S GT ++ DI
Sbjct: 950 SNRSVIVEEKITWPNGLTLDFINDRIYWADAREDYI-EFASLDGTNRHTVLNHDIPHIFA 1008
Query: 7015 VALHGQNMYWTDNRLEKLFRA--TSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRA 7188
+ L + +YWTD + + RA T N+T+L+ ++L DV ++ QP
Sbjct: 1009 MTLFEEYIYWTDWETKSINRAHKTQGTNKTTLI-------STLHRPMDVHIYHPYRQPEV 1061
Query: 7189 -SSPCQITDNLRKSPCTQLCFATPG 7260
+ PCQ T+N C+ LC +PG
Sbjct: 1062 LNHPCQ-TNN---GGCSNLCLLSPG 1082
Score = 124 bits (312), Expect = 5e-26
Identities = 92/301 (30%), Positives = 119/301 (38%), Gaps = 42/301 (13%)
Frame = +1
Query: 325 CIAEYQRCDNITDCADGSDEKDCPASTVDCSS-----------------QNVFMCADGRQ 453
CI CD DC D SDE C V S F C DG
Sbjct: 313 CIGHQFWCDGTDDCGDHSDELPCNTLLVLISQGLLPNWFAFLLLVTLCKPGEFQCKDG-S 371
Query: 454 CFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFR------CADKTQCIQKSWVCDGS 615
C +CD +C D SDE + S + + F+ + C T C SWVCDG+
Sbjct: 372 CISNFSRCDQVVNCEDASDEMNCQSTDCSRFFRLGVKGASFQSCERTTLCYLSSWVCDGN 431
Query: 616 KDCADGSDEPDTCEFKK--CTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCP 789
DC D SDE + + +K C N F C + RC P + CD +DC + +DE C ++ C
Sbjct: 432 NDCGDFSDEKNCPDKRKLKCPVNFFACPSGRCIPMSWTCDKENDCENGADETHCDKF-CT 490
Query: 790 PGKWNCPGTGHCIDQLKLCDGSKDCADGADE-QQCSQNLCPSLGCQAGCHPSPH------ 948
++ C CI +CDGS DC DG+DE Q+C C Q P H
Sbjct: 491 STQFEC-ANHRCISSHWVCDGSDDCGDGSDEDQKCKSKTCSPEAFQC---PGSHMCVPQR 546
Query: 949 ---GGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQ----LCANHR---PGFTCSCLGD 1098
G+ CP G D+ C N CD +C N + F C D
Sbjct: 547 WKCDGDKDCPDG--ADESVKAGCMYTNST-----CDPENEFMCQNRQCIPKHFVCDLDVD 599
Query: 1099 C 1101
C
Sbjct: 600 C 600
Score = 110 bits (275), Expect = 1e-21
Identities = 130/564 (23%), Positives = 221/564 (39%), Gaps = 37/564 (6%)
Frame = +1
Query: 7231 CTQLCFATPGTQTPTCSCARGVLK-GRTCEEPDTYIMFSDGDKIIDVAIEPDVKASRPLK 7407
C+ C T G+ CSC + + TC+ + + +I+ +A + ++++ P
Sbjct: 1634 CSHSCNNTKGSYK--CSCHKYFTRISDTCKADN----INSSRQILYIADDNEIRSLDP-- 1685
Query: 7408 DPFPEISNLQTF-----------DVDVNLRRVYFV--------VESPVGVNISWFSMNNA 7530
P+ QTF DV V R+++ G ++S S N+
Sbjct: 1686 -GMPDWRYEQTFQGDASVRIDAMDVHVKTNRIFWTNWHTGRISTYELQGPSLSATSSNSH 1744
Query: 7531 ENPRLVFGASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTIASG- 7707
+ R G KE++ + +DW+ +Y+T + +G++ T+ SG
Sbjct: 1745 RHRRQSEGRVTDLQIKELKMPRGIAVDWVAGNLYWTDSGRDVIEVAQMSGQNCKTLISGM 1804
Query: 7708 -DWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAV 7884
D YA+ ++P G ++W+D G P+IE + + G R+ +V E+I P +AV
Sbjct: 1805 IDEPYAIVVNPQRGTMYWADWG-------NHPKIETAAMDGTLRQTLVHENIQWPTGLAV 1857
Query: 7885 DFRNQKIYWADVNRLNIEVADYDGQNRKVIASGYRAK-----SLDIWDRWLYMSDPLSNG 8049
D+ N+++YWAD I DG + + SG + S+DI++ ++Y ++N
Sbjct: 1858 DYFNERLYWADAKLSVIGSVRLDGSDPVISVSGLKNNLLHPFSIDIFEDYIYGVTYINNI 1917
Query: 8050 VFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLC 8229
VFR++K +EN+ + SD+ ++ + C D C+ LC
Sbjct: 1918 VFRVNKFGKGKMENLTTG---------INHASDIVLHHRYKQPEMTNPC--DRKKCEWLC 1966
Query: 8230 TVVADDIGLAASKVQCSCNDTYELVQEPG----KDYPTQCVLRGSNSEPAKECLPPYNFQ 8397
L+ S C+C + Y V + G K PTQ S P++ C + Q
Sbjct: 1967 L-------LSPSGPVCTCPNKY--VADNGTCVEKPVPTQSPF----SPPSEPC----DIQ 2009
Query: 8398 CGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHIDDC 8577
C +G L A +K C P+Y R C +C D K
Sbjct: 2010 CLNGGSCFLNARQVAKCRC------QPSYIGER--------CEINQCRDYCKNGGTCTAS 2055
Query: 8578 GDGSDELDCP---SAVACAEGTFP--CSNGHCINQTKVCDGHNDCHDEQVSDE-SLATCP 8739
G CP + C+ T C NG + + C E D TC
Sbjct: 2056 HAGVPTCRCPKGFTGPTCSRQTCQDYCQNGGSCSVSMGNQPTCSCPSEYQGDRCQYTTCE 2115
Query: 8740 GLPIDCRGVKVRCPNTNICIQPAD 8811
G C N+ C+Q ++
Sbjct: 2116 GF----------CHNSGTCLQTSN 2129
Score = 106 bits (265), Expect = 1e-20
Identities = 76/238 (31%), Positives = 105/238 (43%), Gaps = 18/238 (7%)
Frame = +1
Query: 3055 PNELEAKC-----ACRQGFMI------NKENNHSCQKDPAEK-IEQLCSSNSTQFQCKNG 3198
P++ + KC AC G I +KEN+ C+ E ++ C+S TQF+C N
Sbjct: 444 PDKRKLKCPVNFFACPSGRCIPMSWTCDKEND--CENGADETHCDKFCTS--TQFECANH 499
Query: 3199 RCIPKEWKCDGENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKKCIPAQXXXXXXXX 3378
RCI W CDG +DC D SDE KC +T C+ +C + C+P +
Sbjct: 500 RCISSHWVCDGSDDCGDGSDE----DQKCKSKT-CSPEAFQCPGSHMCVPQRWKCDGDKD 554
Query: 3379 XXXXXXXXVKY-CKDGQKPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNA 3555
VK C +F C N +CIP+ + E E C
Sbjct: 555 CPDGADESVKAGCMYTNSTCDPENEFMCQNRQCIPKHFVCDLDVDCSDGSDESPE-CEYP 613
Query: 3556 TCAANQFSCANGRCI-PIYWLCDGDNDCYDGTDE--DKERCPPVQ--CSALQFRCANG 3714
TC ++F CANGRC+ W CDG+ DC+D +DE RC + C+ F C NG
Sbjct: 614 TCGPDEFRCANGRCLNQKKWECDGEFDCHDHSDEAPKNPRCTSSERTCNDSAFTCLNG 671
Score = 106 bits (264), Expect = 2e-20
Identities = 85/282 (30%), Positives = 112/282 (39%), Gaps = 41/282 (14%)
Frame = +1
Query: 379 DEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQ 558
++ C + C S + F C +G C + S CDG C+D SDEK S N C +
Sbjct: 248 EDNTCSPLNMSCGSVDGFECGNG-DCINYSLTCDGMAHCKDKSDEKQSYCANR-ICKKGY 305
Query: 559 FRCADKTQCIQKSWVCDGSKDCADGSDE---------------PDTCEF----KKCTANE 681
RC + +CI + CDG+ DC D SDE P+ F C E
Sbjct: 306 RRCIN-GRCIGHQFWCDGTDDCGDHSDELPCNTLLVLISQGLLPNWFAFLLLVTLCKPGE 364
Query: 682 FQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCP---------PGKWNCPGTGHCIDQ 834
FQCK+ C RCD +C D SDE C C +C T C
Sbjct: 365 FQCKDGSCISNFSRCDQVVNCEDASDEMNCQSTDCSRFFRLGVKGASFQSCERTTLCYLS 424
Query: 835 LKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSD 1014
+CDG+ DC D +DE+ C L C CPSG + + TC
Sbjct: 425 SWVCDGNNDCGDFSDEKNCPDK--RKLKCPVNFF--------ACPSGRCIPMSW--TCDK 472
Query: 1015 INEC---AEFGYCDQL-------CANHR---PGFTCSCLGDC 1101
N+C A+ +CD+ CANHR + C DC
Sbjct: 473 ENDCENGADETHCDKFCTSTQFECANHRCISSHWVCDGSDDC 514
Score = 98.2 bits (243), Expect = 5e-18
Identities = 65/242 (26%), Positives = 112/242 (45%), Gaps = 7/242 (2%)
Frame = +1
Query: 6616 KSLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWA 6795
+ +A+DW+ N+Y+ D+ R IEV+++ G K L++ + P +I V+P +YWA
Sbjct: 1766 RGIAVDWVAGNLYWT--DSGRDVIEVAQMSGQNCKTLISGMIDEPYAIVVNPQRGTMYWA 1823
Query: 6796 DQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGT 6975
D G P I+ + +DG+ R+ +V I PT L VD ++ +YW+DAK+ I VR G
Sbjct: 1824 DWGNHPKIETAAMDGTLRQTLVHENIQWPTGLAVDYFNERLYWADAKLSVIGSVRLDGSD 1883
Query: 6976 PEL----VRSDIASAAGVALHGQNMYWTDNRLEKLFRATS--KPNQTSLLLSPTTVAASL 7137
P + +++++ + + +Y +FR K +L +
Sbjct: 1884 PVISVSGLKNNLLHPFSIDIFEDYIYGVTYINNIVFRVNKFGKGKMENL-------TTGI 1936
Query: 7138 KDIGDVAVFSSNNQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCA-RGVLKGRTC 7314
D+ + QP ++PC + C LC +P P C+C + V TC
Sbjct: 1937 NHASDIVLHHRYKQPEMTNPCD------RKKCEWLCLLSP--SGPVCTCPNKYVADNGTC 1988
Query: 7315 EE 7320
E
Sbjct: 1989 VE 1990
Score = 94.7 bits (234), Expect = 6e-17
Identities = 96/354 (27%), Positives = 122/354 (34%), Gaps = 74/354 (20%)
Frame = +1
Query: 3550 NATCAA-NQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQCV 3726
N +C + + F C NG CI CDG C D +DE + C C RC NGR C+
Sbjct: 256 NMSCGSVDGFECGNGDCINYSLTCDGMAHCKDKSDEKQSYCANRICKKGYRRCINGR-CI 314
Query: 3727 PLR------------------NHXXXXXXXXXXXXXXXXAVTAESCTPDQFKCVSSGLCI 3852
+ N + C P +F+C G CI
Sbjct: 315 GHQFWCDGTDDCGDHSDELPCNTLLVLISQGLLPNWFAFLLLVTLCKPGEFQC-KDGSCI 373
Query: 3853 PASWKXXXXXXXXXXSDEPKFGCTS-------GRQCSSDQFKCGNGRCILNNWLCDGEND 4011
+ SDE T G + +S Q C L++W+CDG ND
Sbjct: 374 SNFSRCDQVVNCEDASDEMNCQSTDCSRFFRLGVKGASFQSCERTTLCYLSSWVCDGNND 433
Query: 4012 CGDGSDESSERGCKTSMNARKCPFEHVAC--------------ENDQET----------- 4116
CGD SD E+ C KCP AC END E
Sbjct: 434 CGDFSD---EKNCPDKRKL-KCPVNFFACPSGRCIPMSWTCDKENDCENGADETHCDKFC 489
Query: 4117 -----------CIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGC---------SFKC 4236
CI H +CDG C G+DE +C CS + C +KC
Sbjct: 490 TSTQFECANHRCISSHWVCDGSDDCGDGSDEDQKCKSKTCSPEAFQCPGSHMCVPQRWKC 549
Query: 4237 ---HNSPNGPICSCPFGEQLVNKTKCEPENECLDSSSCSQRCKDEKHGFTCSCD 4389
+ P+G S G N T C+PENE + C R KH F C D
Sbjct: 550 DGDKDCPDGADESVKAGCMYTNST-CDPENEFM----CQNRQCIPKH-FVCDLD 597
Score = 89.4 bits (220), Expect = 2e-15
Identities = 62/223 (27%), Positives = 105/223 (46%), Gaps = 8/223 (3%)
Frame = +1
Query: 4672 EGIALDWVGRNLYWVDSSLNTIEVANLEDPK----QRTLLVHQNVSQ-PRGIAVDPRKGV 4836
EG+A LYW + +TI ++ + R +V+ + PR +D + +
Sbjct: 36 EGLAYHRGWDTLYWTSYTTSTITRHTVDQSRTVAYNRDTVVNMSAEDHPRAFVLDECQDL 95
Query: 4837 MFWTDWG-QNPCIERASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVN 5013
MFWT+W Q P I RAS++G + +I+ + I PN +A+D+ +++YF+D+ LD I+
Sbjct: 96 MFWTNWNEQAPSIMRASLNGANVLVIIGSDIKTPNGLAIDHRAEKLYFSDATLDKIERCE 155
Query: 5014 YDGSGRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSK 5193
YDGS R +L + HP LA++ D ++++D V S++ S ++
Sbjct: 156 YDGSSRYVLLKNEPV--HPFGLAVYGDYIFWTD------WVRRAVLRADNSQWASSLWAN 207
Query: 5194 ALGVVAVHPVLQPVIKNNPCSTN--PCSHLCLLNNKNTFTCKC 5316
+ +PC TN C LCL + C C
Sbjct: 208 DTN----------NCEFSPCRTNNGGCQDLCLPTSDGRVNCSC 240
Score = 86.7 bits (213), Expect = 2e-14
Identities = 89/384 (23%), Positives = 154/384 (39%), Gaps = 16/384 (4%)
Frame = +1
Query: 5254 STNPCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKPFLVI-----IQKTNVFG--- 5409
+T PCS C+ N +F C C G + +P+L+ ++K N+ G
Sbjct: 744 TTYPCSQRCI-NTHGSFHCLCVDGFQ---------PKEEPYLIFANRYYLRKLNLDGSNY 793
Query: 5410 --IEMNSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTD-S 5580
I+ ++ ET + ++ N F + + +TT S
Sbjct: 794 TLIKQVRSAPAETMRWSSLLGPCARFNPFRHFQGLNNAVALDFHYAEQMIYWTDVTTQGS 853
Query: 5581 AIYRSTVNGGNKTKMFSSAV--PDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRS 5754
I R +NG N + +++ PD L DW G NL +K TIE+ + G YR+
Sbjct: 854 MIRRMHMNGSNMEVLHRTSLSNPDG---LAVDWVGGNLYWCDKGRDTIEVSKLNG-AYRT 909
Query: 5755 VILSNDQSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLA 5934
V++++ Y++W D G + + R G+DGSN VI +
Sbjct: 910 VLVNSGLREPRALAVDVRYR-----YLYWSDWGD---NPHIGRIGMDGSNRSVIVEEKIT 961
Query: 5935 ELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADS 6114
+ + +D N R+Y+++A+ I + DG +RH VL+ + + + +++ D
Sbjct: 962 WPNGLTLDFINDRIYWADAREDYIEFASLDGTNRHTVLNHDIPHIFAMTLFEEYIYWTDW 1021
Query: 6115 AFDSIEVATINGDSQPPQWTHFKKDVENLANIKALQP--RASSSGHPCHINNGNCDHICI 6288
SI A +Q T + ++ P + HPC NNG C ++C+
Sbjct: 1022 ETKSINRA---HKTQGTNKTTLISTLHRPMDVHIYHPYRQPEVLNHPCQTNNGGCSNLCL 1078
Query: 6289 PLMFAQRTCTC-ANGYVKDGQTSC 6357
C C N Y+ Q +C
Sbjct: 1079 LSPGGGYKCACPTNFYLASDQRTC 1102
Score = 84.7 bits (208), Expect = 6e-14
Identities = 59/220 (26%), Positives = 102/220 (45%), Gaps = 4/220 (1%)
Frame = +1
Query: 1510 RRTVLLADGLTLPLDIALDPLRGEMFFTNQLK----LEAAAMDGTNRRTLVNTHTHQVSG 1677
R TV+ P LD + MF+TN + + A+++G N ++ + +G
Sbjct: 72 RDTVVNMSAEDHPRAFVLDECQDLMFWTNWNEQAPSIMRASLNGANVLVIIGSDIKTPNG 131
Query: 1678 IVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTR 1857
+ +D A+++Y+ D +D++E +Y G+ R ++ + V HPFGLA++ Y++WTDW R
Sbjct: 132 LAIDHRAEKLYFSDATLDKIERCEYDGSSRYVLLKNEPV--HPFGLAVYGDYIFWTDWVR 189
Query: 1858 LGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCE 2037
V++ + LW+N NN + P + G + L + + N C
Sbjct: 190 RAVLRADN-SQWASSLWANDTNN------CEFSP-CRTNNGGCQDLCLPTSDGRVNCSCR 241
Query: 2038 GMCILSKDNGGFGVGYKCACPIGQKLVNGKRCIDSIDYLL 2157
G L +DN + C G + NG D I+Y L
Sbjct: 242 GDRHLLEDNTCSPLNMSCGSVDGFECGNG----DCINYSL 277
Score = 79.0 bits (193), Expect = 3e-12
Identities = 48/163 (29%), Positives = 75/163 (45%)
Frame = +1
Query: 5833 VFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAIDTTNTRVYFSEAKAGRISS 6012
+FW + A + RA L+G+N LVI +D+ + +AID ++YFS+A +I
Sbjct: 96 MFWTNWNEQAPS--IMRASLNGANVLVIIGSDIKTPNGLAIDHRAEKLYFSDATLDKIER 153
Query: 6013 VTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAFDSIEVATINGDSQPPQWTHFKKDV 6192
YDG R+ +L + P GLA YGD +F+ D + A + D+ + + D
Sbjct: 154 CEYDGSSRYVLLKNEPVHPFGLAVYGDYIFWT----DWVRRAVLRADNSQWASSLWANDT 209
Query: 6193 ENLANIKALQPRASSSGHPCHINNGNCDHICIPLMFAQRTCTC 6321
N PC NNG C +C+P + C+C
Sbjct: 210 NN------------CEFSPCRTNNGGCQDLCLPTSDGRVNCSC 240
Score = 74.3 bits (181), Expect = 8e-11
Identities = 77/310 (24%), Positives = 130/310 (41%), Gaps = 10/310 (3%)
Frame = +1
Query: 2404 MSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRD-PVSVVVHPWKGL 2580
++ DW++ LY+ D+ R+ +EV ++ + LI+ + D P ++VV+P +G
Sbjct: 1768 IAVDWVAGNLYWTDSGRDVIEVAQMSGQNC--------KTLISGMIDEPYAIVVNPQRGT 1819
Query: 2581 LFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDF 2760
+++A+ I +DG Q + + + P+ +A+D+ RL W D L I +
Sbjct: 1820 MYWADWGNHPKIETAAMDGTLRQTLVHENIQWPTGLAVDYFNERLYWADAKLSVIGSVRL 1879
Query: 2761 DGKNVV--KLDIDNPI--PVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADE 2928
DG + V + N + P +I I +YIY V + RV+ K G G G +
Sbjct: 1880 DGSDPVISVSGLKNNLLHPFSIDIFEDYIYGVTYINNIVFRVN-KFGKGKMENLTTGINH 1938
Query: 2929 RSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINK 3108
S L H P+ +PC +C LC +PS C C ++
Sbjct: 1939 ASDIVL----HHRYKQPE--MTNPCDRKKCEWLCLLSPS-------GPVCTCPNKYV--- 1982
Query: 3109 ENNHSCQKDPAEKIEQLC-SSNSTQFQCKN-GRCI---PKEWKCDGENDCLDESDEIDEK 3273
+N +C + P S QC N G C + KC + + E EI++
Sbjct: 1983 ADNGTCVEKPVPTQSPFSPPSEPCDIQCLNGGSCFLNARQVAKCRCQPSYIGERCEINQC 2042
Query: 3274 GDKCFHETEC 3303
D C + C
Sbjct: 2043 RDYCKNGGTC 2052
Score = 65.1 bits (157), Expect = 5e-08
Identities = 61/232 (26%), Positives = 102/232 (43%), Gaps = 5/232 (2%)
Frame = +1
Query: 6634 WINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTET-PSSIAVDPVSRYLYWADQG-Q 6807
W +Y I R ++ S+ R ++ E P + +D ++W + Q
Sbjct: 49 WTSYTTSTIT----RHTVDQSRTVAYNRDTVVNMSAEDHPRAFVLDECQDLMFWTNWNEQ 104
Query: 6808 KPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTP-EL 6984
P+I R+ L+G+ VI+ S I P L +D ++ +Y+SDA +D I R G + L
Sbjct: 105 APSIMRASLNGANVLVIIGSDIKTPNGLAIDHRAEKLYFSDATLDKIERCEYDGSSRYVL 164
Query: 6985 VRSDIASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVF 7164
++++ G+A++G ++WTD + RA + +SL + T
Sbjct: 165 LKNEPVHPFGLAVYGDYIFWTDWVRRAVLRADNSQWASSLWANDT--------------- 209
Query: 7165 SSNNQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCA--RGVLKGRTC 7314
NN SPC+ T+N C LC T + CSC R +L+ TC
Sbjct: 210 --NN--CEFSPCR-TNN---GGCQDLCLPTSDGRV-NCSCRGDRHLLEDNTC 252
Score = 54.3 bits (129), Expect = 9e-05
Identities = 33/105 (31%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = +1
Query: 4546 ALAWDSLTDRIYWSDIREK--KILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVD 4719
A D D ++W++ E+ I+ A+ NG N V I + G+A+D LY+ D
Sbjct: 86 AFVLDECQDLMFWTNWNEQAPSIMRASLNGANVLVIIGSDIKTPNGLAIDHRAEKLYFSD 145
Query: 4720 SSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDW 4854
++L+ IE + + LL ++ V P G+AV +FWTDW
Sbjct: 146 ATLDKIERCEYDGSSRYVLLKNEPV-HPFGLAV--YGDYIFWTDW 187
Score = 52.0 bits (123), Expect = 4e-04
Identities = 52/200 (26%), Positives = 75/200 (37%), Gaps = 17/200 (8%)
Frame = +1
Query: 3817 DQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKCGNGRCILNNWLC 3996
D F+C +G CI S SDE + C + R C +C NGRCI + + C
Sbjct: 263 DGFEC-GNGDCINYSLTCDGMAHCKDKSDEKQSYCAN-RICKKGYRRCINGRCIGHQFWC 320
Query: 3997 DGENDCGDGSDESSERGCKT----------------SMNARKCPFEHVACENDQETCIPL 4128
DG +DCGD SDE C T + C C++ +CI
Sbjct: 321 DGTDDCGDHSDELP---CNTLLVLISQGLLPNWFAFLLLVTLCKPGEFQCKDG--SCISN 375
Query: 4129 HQLCDGKTHCPGGTDEGGRCARDLCSADRAGCSFKCHNS-PNGPICSCPFGEQLVNKTKC 4305
CD +C +DE + D R G S +C ++ C
Sbjct: 376 FSRCDQVVNCEDASDEMNCQSTDCSRFFRLGVKGASFQSCERTTLC-------YLSSWVC 428
Query: 4306 EPENECLDSSSCSQRCKDEK 4365
+ N+C D S + C D++
Sbjct: 429 DGNNDCGDFSD-EKNCPDKR 447
Score = 50.1 bits (118), Expect = 0.002
Identities = 42/180 (23%), Positives = 84/180 (46%), Gaps = 4/180 (2%)
Frame = +1
Query: 6469 SITGVDYDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTI----KSLAIDW 6636
S+ G+ Y T+Y S IT +T+ +S A RD++ +++ ++ +D
Sbjct: 34 SVEGLAYHRGWDTLYWT--SYTTSTITRHTVDQSRTVAYNRDTVVNMSAEDHPRAFVLDE 91
Query: 6637 INYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPT 6816
M++ N + + +I + L+G +++ + +TP+ +A+D + LY++D
Sbjct: 92 CQDLMFWTNWNEQAPSIMRASLNGANVLVIIGSDIKTPNGLAIDHRAEKLYFSD-ATLDK 150
Query: 6817 IQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPELVRSD 6996
I+R DGS R V++ + P L V I+W+D + R ++ L +D
Sbjct: 151 IERCEYDGSSRYVLLKNEPVHPFGLA--VYGDYIFWTDWVRRAVLRADNSQWASSLWAND 208
Score = 48.5 bits (114), Expect = 0.005
Identities = 54/237 (22%), Positives = 95/237 (39%), Gaps = 6/237 (2%)
Frame = +1
Query: 5659 LGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVILSNDQSXXXXXXXXXXXXXXXKGYVF 5838
+ DW NL + IE+ + G+ +++I +G ++
Sbjct: 1768 IAVDWVAGNLYWTDSGRDVIEVAQMSGQNCKTLI------SGMIDEPYAIVVNPQRGTMY 1821
Query: 5839 WLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAIDTTNTRVYFSEAKAGRISSVT 6018
W D G K+ A +DG+ + ++ +A+D N R+Y+++AK I SV
Sbjct: 1822 WADWGN---HPKIETAAMDGTLRQTLVHENIQWPTGLAVDYFNERLYWADAKLSVIGSVR 1878
Query: 6019 YDGQDRHYVLSDGGRQPNGLAFYGDRLF----YADSAFDSI--EVATINGDSQPPQWTHF 6180
DG D V+S G + N L + +F Y + ++I V T
Sbjct: 1879 LDGSDP--VISVSGLKNNLLHPFSIDIFEDYIYGVTYINNIVFRVNKFGKGKMENLTTGI 1936
Query: 6181 KKDVENLANIKALQPRASSSGHPCHINNGNCDHICIPLMFAQRTCTCANGYVKDGQT 6351
+ + + + QP + +PC + C+ +C+ L + CTC N YV D T
Sbjct: 1937 NHASDIVLHHRYKQPEMT---NPC--DRKKCEWLCL-LSPSGPVCTCPNKYVADNGT 1987
Score = 39.7 bits (91), Expect = 2.2
Identities = 44/165 (26%), Positives = 55/165 (32%), Gaps = 18/165 (10%)
Frame = +1
Query: 667 CTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLC 846
C N Q RCQP G+ + ++C +Y C G C
Sbjct: 2016 CFLNARQVAKCRCQPSYI--------GERCEINQCRDY--------CKNGGTCTASHAGV 2059
Query: 847 DGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGE---CTCPSGYKLDDRFHRTCSDI 1017
+ C G CS+ C CQ G S G C+CPS Y+ D + TC
Sbjct: 2060 PTCR-CPKGFTGPTCSRQTCQDY-CQNGGSCSVSMGNQPTCSCPSEYQGDRCQYTTCEGF 2117
Query: 1018 NECAEFGYCDQ--------LCANHRPGFTCSC-------LGDCFT 1107
C G C Q LC+N G C G CFT
Sbjct: 2118 --CHNSGTCLQTSNGTKLCLCSNQYVGHQCELDKCQFCGTGKCFT 2160
>gi|39586294|emb|CAE66705.1| Hypothetical protein CBG12050
[Caenorhabditis briggsae]
Length = 4856
Score = 1109 bits (2868), Expect = 0.0
Identities = 1060/4270 (24%), Positives = 1697/4270 (38%), Gaps = 317/4270 (7%)
Frame = +1
Query: 502 LSDEKDSCSR--NHTACFQYQFRCADKT----QCIQKSWVCDGSKDCADGSDEPDTCEFK 663
LSD DS + N ++C C T +C + W CDG DC D SDEP TC+ +
Sbjct: 19 LSDSPDSSLKKANTSSCVPPMRECDSGTPSGPKCYPEQWFCDGYPDCRDNSDEPPTCK-R 77
Query: 664 KCTANEFQCKNKRCQPRKFRCDYYDDCG-------DNSDEDE--CGE-YRCPPGKWNCPG 813
C NEF CK +C PR + CD DCG D SDE C + C ++ C
Sbjct: 78 ACLENEFVCKTGKCLPRGYLCDGQLDCGRFPDGLQDRSDESRELCNQPLNCEHNEYACAA 137
Query: 814 TGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDR 993
+ C+ K CDG DC+DG+DE +N+ + C+ G + G +C CP L+++
Sbjct: 138 SAQCVPLFKFCDGKLDCSDGSDEVCRVKNISTANDCEYGAAITIDGIKCYCPKNKFLNEK 197
Query: 994 FHRTCSDINECAEF-----GYCDQLCANHRPG-FTCSCLGDCFTL-QMEHGPGKDNLTM- 1149
C +N+C C Q C +++ G F+C C T+ H + ++++
Sbjct: 198 --GKCEFVNQCDRLKNGLPPACSQGCTDNKNGTFSCFCFDPRLTVANGTHCVAEKDVSIP 255
Query: 1150 --------RGYCVSNNADKMKLFVARREG------LYRLNPKNPDEEVKKLASGEF---- 1275
+ Y + N + R G L +P P+ +V L E
Sbjct: 256 SVAILTKQKIYTIQNGTMSNYSSLPRPLGKPGALTLVFQHPDFPEAKVPILCLSEAPTSN 315
Query: 1276 -----------------IYGIDFDYGDRKIFWTDRLAHSAFSADVD--------DEGEIS 1380
Y +DFD + D ++ D D +IS
Sbjct: 316 QSYITCGNVEGSEPVTKSYAVDFDISAIHMIRFDNFGNNWIFTDASYYIFICKHDSVKIS 375
Query: 1381 QIKKLSLKSLVYPRCLAVDWITNTLYIIES-----GSRRIDVSSYDGERRTVLLADGLTL 1545
+ + ++ + + D + ++ +S G RIDV+S GER L +T
Sbjct: 376 KCHTFAAGAMGTLQDVQYDGVNGQFFVTDSDYFQQGIWRIDVAS--GERNR-LTTQPITS 432
Query: 1546 PLDIALDPLRGEMFFTNQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPK 1725
P +A+DP K +Y+VD
Sbjct: 433 PA-LAIDPF-----------------------------------------TKTLYYVDSS 450
Query: 1726 VDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFGS--DTK 1899
+ +++IDY N RIV G + T+L + + F + D +
Sbjct: 451 ANSIKAIDYNSNFSRIVVSGRIA----------------KEVTQLDYAEGKLFATLRDNR 494
Query: 1900 LLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKI--------------ENPCTNADCE 2037
+ +N + + + + P G + M++ N C A C+
Sbjct: 495 VFVANALESDSEAVLKTWQEITPPSNGGPNKVIMEVFHFRRNANAWKNKGRNICKAASCD 554
Query: 2038 GMCILSKDNGGFGVGYKCACPIGQKLVNGKRCIDSID--------YLLFSSNKIVRGIFP 2193
+CI G + C C G L+ + ID L+ + + R
Sbjct: 555 DICI-----GHIEKTFSCLCRDG--LIQKENKCQEIDQNELKDKEILILAQLRPARVKVL 607
Query: 2194 EINEKALAEAV-LPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAP 2370
N+ E + +P ++R + F D G D+ +++ + D
Sbjct: 608 GFNKDYQTEDIGIPDILAAKRPSAITF----DPKGKRILMYDLKRHSLVVQKMDQSNTTF 663
Query: 2371 VLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRDPV 2550
+T M++D+ S LY D R + V ++ + +++ R + +P
Sbjct: 664 HGLTGIMNCEGMAYDYTSDNLYMTDQKRKLITVQRLSNLSV---QKIIVR---GNMSNPR 717
Query: 2551 SVVVHPWKGLLFYA--------EAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAE 2706
++ VH K LF+ +A PA I R +DG + + + + + +D
Sbjct: 718 AIAVHVAKSYLFWGSWSEDRQNDATTPAMIERSKLDGSERKTLVSKNSMWINGLTLDLKN 777
Query: 2707 NRLCWGDTLLKTISCMDFDG--KNVVKLDIDN-PIPVAITIMNEYIYYVHQRPYSIRRVH 2877
+ L W D I + ++G + V+ +D P + + +I++ + +++RV
Sbjct: 778 DFLYWCDAYRNVIERIRWNGADREVIIQGVDKISHPYGLAFFDNHIFFTEFKRGAVKRV- 836
Query: 2878 KKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPC--RASQCTQLCFATPSES 3051
N V+E ++F L + PC +S C CFAT +
Sbjct: 837 --NVNFPDQVQEIFQYSATVFELAVFKNSL-----SKSTSPCSTSSSNCEHFCFATSCKG 889
Query: 3052 HPNELEAKCACRQGFMINKENNHSCQKDPAEKIEQLCSSNSTQFQCKNGR-CIPKEWKCD 3228
KC C G + +N C KD + C + +F C N R CIPK CD
Sbjct: 890 SVGCEPVKCGCADGMKL--VDNGKCVKDEHWEDPNGCDED-REFTCLNSRKCIPKANLCD 946
Query: 3229 GENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVK 3408
G++DC D SDE D G + +C N +C +T CIP +
Sbjct: 947 GDDDCGDGSDE-DSNG--ICKDFKCVGNKFQCDST-TCIPLEFLCDGKSDCNDGTDELET 1002
Query: 3409 YCKDGQKPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNATCAANQFSCAN 3588
CK C+ +F+C N +CI ++ K ++ + + C +F C
Sbjct: 1003 MCKTVPDVRCSVGQFRCSNTKCI-DKSKRCNGIQDCENGSDEEDCPRSKLCTPTEFRCGT 1061
Query: 3589 GRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQ-CVPL---RNHXXXXX 3756
G CI +CDG C DG DE QFRCAN + C+ + +
Sbjct: 1062 GLCIKQSQVCDGKMQCLDGLDEKHCEENNSCIKGRQFRCANKQSTCLDMIFQCDGVPDCE 1121
Query: 3757 XXXXXXXXXXXAVTAESCTP-DQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGR 3933
T+ SC +QF C + G C+ + DE + C
Sbjct: 1122 DESDESPEFCKGNTSSSCAKMNQFMC-ADGKCLRSFQLCDGFPDCLTGEDEKE--CPPSM 1178
Query: 3934 QCSSDQFKCGNG-RCILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQ 4110
S+ C NG +C+ CDG +DCGD SDES + +C C++ +
Sbjct: 1179 CNSATHLSCANGNKCVSKELECDGVDDCGDKSDESHCDDIRMEAALLRCIPPMYKCQSGR 1238
Query: 4111 ETCIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCSFKCHNSPNGPICSCPFGEQLV 4290
CI QLCDGK CP G DEG C+ LC++ GCS C +P+GPICSCP E +
Sbjct: 1239 FQCISDKQLCDGKNDCPSGDDEGMWCS-FLCNSTEIGCSHTCRATPSGPICSCP-DEYFL 1296
Query: 4291 NK--TKCEPENECLDSSSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYV 4464
K C ++ C CSQ C + C C++GY+L D+ +C+ D + IY
Sbjct: 1297 EKDGVTCAKKDPC-RFGQCSQHCMSQGSRHFCYCEDGYKLLNDRISCRTVDPKTEFMIY- 1354
Query: 4465 SNRNRIYYSDHKLDNWHTFGAIVENAIALAWDSLTDR---IYWSDIREKKILSA---NRN 4626
SNR+ I + + NAIAL + L + +YW+D+ KI S R
Sbjct: 1355 SNRHEIRMIQATSPGSIPLISSLTNAIALDFKYLNNGSLIVYWTDLSSDKIYSGLMDQRT 1414
Query: 4627 GTNATVFIADGLDITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPR 4806
+ ++ G+ EGIA+DW+ N+YW+DS L+TI+V + ED +R +V++N+ R
Sbjct: 1415 IMYSRTIVSYGVFNAEGIAVDWITGNIYWIDSHLDTIQVLS-EDGTKRATVVNENMGNAR 1473
Query: 4807 GIAVDPRKGVMFWTDWGQ-NPCIERASMDGTDRQIIVK----TKIYWPNTIALDYTTDRV 4971
+A+D +G+MFWTDW + NP IER ++ G +R + K + WPN IALD T RV
Sbjct: 1474 SLAIDVEEGLMFWTDWEEANPRIERCTLAGKNRATVWKISNVAQAGWPNGIALDTITKRV 1533
Query: 4972 YFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYP 5151
Y+ D+K D I + YDG VL + + H + ++ D +Y+SD R + K+
Sbjct: 1534 YWVDAKSDSIHTITYDGRDHVLVLRDPERLGHCFGIDVYGDNVYFSDWRTNTISTVNKFG 1593
Query: 5152 NGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTNPCSHLCLLNNKNTFTCKCPMGEK 5331
G + ++ + VH Q N C C+ +CL + +N +C+C +
Sbjct: 1594 KGEVT-IVERVATQPFSLKIVHRSKQKRQLKNMCDGFKCNGICLNDGRNKASCQCTNIQT 1652
Query: 5332 LDASGKKCIDDAKPFLVIIQKTNVFGIEMNSASEKETPVLAGMVPLSGLGNAFDAAYDAL 5511
G C+ D + L+I K V G P+++G N D +
Sbjct: 1653 TTDDG--CV-DVEQTLLIATKNAVRGFSTIPPHPHAFPLVSG----KQFENIRDVG--SF 1703
Query: 5512 SEEMFILEHTNHAKTLAQIT--TDSAIYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRN 5685
+ IL+ L +T D I + + + M V + Y F +G
Sbjct: 1704 QNRLQILDDLTDQVVLVNLTGEADEQILATGSDMYGVSGMTIDPVLGNTYFTFFSNDG-- 1761
Query: 5686 LVVGNKITQTIEIIRTQGKQYRSVILSNDQSXXXXXXXXXXXXXXXKGYVFWLDRGGGAA 5865
T IE+I +G + ++ S K ++W + G
Sbjct: 1762 -------TGRIEVINAEGTSKKVLVESGTFPGMRFPRGIIFVNSTKK--LYWFEAGTTPY 1812
Query: 5866 DAKVARAGLDGSNPLVIASNDLAELDHIAIDTTNTRVYF-SEAKAGR-------ISSVTY 6021
A +G+ L + S L ++ + +D N+++Y+ S+ K + I+ +
Sbjct: 1813 TIFTMSAAGNGAKKLKLNSTLLTKVYNPTVDQFNSKLYWISQGKIVQFNPATEIINEIEV 1872
Query: 6022 DGQDRHYVLSDGGRQPNGLAFYGDRLFYADS------AFDSIEVATINGDSQPPQWTHFK 6183
G D++ V S Q NG G+ + A+ + + G Q P + +
Sbjct: 1873 TGGDKN-VSSIAVDQKNGDILIGEFVRIANQTTVRRLSMKGTKSTQTGGVMQVPLHSSVQ 1931
Query: 6184 KDVENLANIKALQPRASSSGHPCHINNGNCDHICIPLMFAQRTCTCANGYVKDGQTSCKL 6363
+ + K ++ + C C+ +C+ C C+ GY+ + C+
Sbjct: 1932 FFLATIDTSKVVK----NIPDECK----TCESLCLSKDQKTFECACSQGYILE-NGKCRS 1982
Query: 6364 FDESFVIVATKTKV--IGYPIDETQSKGVAM-------EPIGGLSITGVDYDYESKTIYV 6516
++ + V V +G+ D+ + V + IG I + D + IYV
Sbjct: 1983 PEKRVIYVTDDGSVQSVGWYKDQKSGEMVQVMRAHSLHSDIGKKRIVRLVADTKKDVIYV 2042
Query: 6517 AEASGINKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINYNMYFINHDAERTNIEVS 6696
+ + + + A + S S I ++++D + ++ ++ + ++
Sbjct: 2043 -----VTRQNEVWKCATNGSFAHMIYSTTSHRIAAISLDRVTGHLLVSARESVSSKGDIV 2097
Query: 6697 KLD------GTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQRSFLDGSRREVI 6858
LD G Y +++ + + P IAVDP ++WA I+ + DGS + I
Sbjct: 2098 LLDPDRYQEGMY-SVIVEDEEKVPYEIAVDPPKGKIFWA---SAHCIKAANYDGSEPKCI 2153
Query: 6859 VSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPE-----LVRSDIASAAGVAL 7023
V+ + VD + + D++ + V G + +A ++
Sbjct: 2154 VAKSAV--ATIAVDEDRSRLCYMDSERAAVDCVDYNGENEQRNVAMFKAQGLAEVVSLSF 2211
Query: 7024 HGQNMYWTD--NRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRASSP 7197
+G M++ D N + R + + + + + + + + F +Q ++
Sbjct: 2212 NGDEMFFFDKFNSSGSIVRGIVQKDGSVVFVDSIKKQLPRQKL-RIIDFDIMDQKKSVLF 2270
Query: 7198 CQITDNLRKSPCTQLCFATPGTQT--PTCSCARGV-LKGRTCEEPDTYIMFSDGDKIIDV 7368
++N C LC P + C C V + TC + +T++ F+ I +
Sbjct: 2271 TACSNN--NGGCEHLCITVPFEDSIKKKCICVHSVPTEDGTCGQSNTFVAFTRFTSIEFL 2328
Query: 7369 AIEPDVKAS--RPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAENPR 7542
+ P V A + + ++ + D + R+YF ++ F
Sbjct: 2329 SATPGVMAPPYKQIASASCAMTKIGAIAADNSRGRIYFADYEKFRISAVNFD-------- 2380
Query: 7543 LVFGASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLST--------- 7695
G A+++R + M D + +++Y+ + + ID A +L
Sbjct: 2381 ---GTGCVVIAEDVRVVPSMAYDEVNRELYYVSANPAGIWRIDVADNNLENYPTEPKLVL 2437
Query: 7696 -IASGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPA 7872
+ + D LAIDPC LLF+ T+ + IER+ +G R+ I+ E +
Sbjct: 2438 LLTNRDRPRHLAIDPCRMLLFF------TNNAITGSVIERAYFSGYKREQILQEDLHDLR 2491
Query: 7873 AIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGYRAKS-----LDIWDRWLYMSDP 8037
+A+D +K+Y++D I D DG NR+V+ S S L+I++ + +D
Sbjct: 2492 GLAIDLETEKLYFSDSKDFRISRCDLDGCNREVVISNSDNPSIHPFELEIYENEIIFTDW 2551
Query: 8038 LSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGC 8217
+ V I+K SG + +P L V + T+N C + C
Sbjct: 2552 VKRAVSGINKISGVEHRLMNRATEVPVGLVVVDVSKEFCTKNP---------CYENELKC 2602
Query: 8218 DQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSEPAKECLPPYNFQ 8397
C ++AD + C+CN L D T C + K+C F+
Sbjct: 2603 GDYCRLMAD------GQATCACNGERRL----SADNKT-C----TGDVDEKKC-AENEFK 2646
Query: 8398 C-GDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHIDD 8574
C CI TCD DC DE+ YC++R C Y C N CI +K CN +D
Sbjct: 2647 CLHSDKCIPYEDTCDQYNDCPMFDDEDAKYCSSRVCRPGYFDCGNGLCISESKVCNRFND 2706
Query: 8575 CGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDE---SLATCPGL 8745
C + DE +C C++ F C +G+CI C+ DC+D SDE C L
Sbjct: 2707 CINFHDENNC----TCSKSEFKCDSGNCIPGEDRCNHVQDCND--ASDEIGCPYRNCSSL 2760
Query: 8746 PIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQL---FCMNQQCAQHYVRCPSG- 8913
+ C +T+ CI P+ CDG +DC D +DE F N+ C S
Sbjct: 2761 VEFGMSDLINCASTSQCIHPSWKCDGTNDCYDGSDELDCLVEFDFNKGSVSPPRSCDSAT 2820
Query: 8914 --------RCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRA 9069
C+P W+CDG DC+DG DE NC A
Sbjct: 2821 QFPCLATRNCMPNRWRCDGQPDCADGSDE--ANCEQKA---------------------- 2856
Query: 9070 FIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCA 9249
C EF C S K CIP CDG C
Sbjct: 2857 -------------------------CNSFEFTCESTKK-------CIPLEQKCDGRSDCP 2884
Query: 9250 GGEDESTELCKTEKKECN-KGEFRCSNQHCIHSTWECDGDNDCLD-----GSDEHANCTY 9411
GEDE++ C TE N FRC+N CI W CDG +DCLD GSDE
Sbjct: 2885 NGEDENS--CDTECDSKNGNSTFRCTNHRCIPMAWRCDGTDDCLDNAKSLGSDEMDCAPG 2942
Query: 9412 SSCQPDFFQCANHKCVP----NSWKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQ 9579
+ +C + CV + CDG DC DG DE++C A +C ++
Sbjct: 2943 KTSFHVPSRCTDETCVVACELTAVLCDGIKDCNDGFDEENC------ASLDRQCKLNEWM 2996
Query: 9580 CTSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKP-------------------- 9699
C SG+CI+ A +CD + DC D SDE +++ CSL+E P
Sbjct: 2997 CDSGQCINSAHLCDSSVDCIDGSDE----WVEICSLSEPPKRGCPNGWSCVLKNGTIGCL 3052
Query: 9700 ----LCE--QKCMD---------------------------MKIGYK-CDCFEGFAIDIS 9777
LC+ + CM G++ C C EGF +
Sbjct: 3053 QEHQLCDGRKDCMSGIDEQCDLPQGNCSSARNSCEQPWNCKRNAGFETCSCDEGFHLSPY 3112
Query: 9778 DQKSCHNVNECYEGISGCSQKCDDKIG-SYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLL 9954
D+++C C + + CS C D+ ++C C G+ LS + C+R + EP L+
Sbjct: 3113 DKRTCLRSPSCPK--ANCSHFCIDRRDVGHQCFCAPGFILSDNQRDCRRND-TIEPEILM 3169
Query: 9955 ANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPL 10134
+ H ++ +IDG+ N V+LD D+ Y D + + M +
Sbjct: 3170 VSGHRLKLFTIDGHAKATLLSNLTNGVALDYDVKSDLVYWTDVTNSG-NKAGITSMSNQP 3228
Query: 10135 SSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDR-IQQPKA 10311
+Y + G +GIAVDW+GR +Y +R +I VC++ GRF + L++ + P+A
Sbjct: 3229 YTYRIINSLPTKGIDGIAVDWLGRHIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRA 3288
Query: 10312 IVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLF 10491
IV+ P + LF+T+W +IGR+ +DGS E+ L + + WPNA+A+D + RL+
Sbjct: 3289 IVLDPIQALLFWTDWGASAHIGRMNMDGSNEM----IILEDRTIRWPNALAVDAPAQRLY 3344
Query: 10492 WGDAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKN 10671
+GDAH + I ++DG RR + H+ ++ VF+DY+YW+DW+ + R K TG N
Sbjct: 3345 FGDAHRDYIASCNYDGTKRRMVLRNSVRHIFALAVFEDYIYWSDWHNHTIERVHKITGDN 3404
Query: 10672 ETILKKTVQL-PNDLRIVHPMRQ-----PAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCP 10833
+L + Q P ++VHP Q +PC C +LC+ + +TC C
Sbjct: 3405 RKVLIQDKQYRPMGFKVVHPSFQNMGSMKTAKHPC-SQPARCDNLCIPASSPEAFTCMCA 3463
Query: 10834 DQFVLLSDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPG--ESICGQR 11007
F SD ++C C F C KCI W CDG+ DC DG DE + +C Q
Sbjct: 3464 QGF--RSDGRSCVSECKPNDFVC-TKTYKCIASWWRCDGQDDCGDGEDEGYFLKGVCPQF 3520
Query: 11008 ICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXXEQNCDKACDPWMFKCAATGRCIPRRFTX 11187
C G+F C +N C C C+
Sbjct: 3521 PCDPGQFLCPK--------------------SPRNTTAQCLYASKLCDGVKDCL------ 3554
Query: 11188 XXXXXXXXRSDEADTLCMSAERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXETPECA 11367
DE T C E CT +F+C + K + C
Sbjct: 3555 -------EGEDEEKTFCEHFE--CTESQFKCGDKKKCIPLTSVCDKEKDCDDGSDERSCE 3605
Query: 11368 QIECKKGWTRC-----SSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGE-----F 11517
CK + C S +CIP +C+G+DDC + DE TC +GE F
Sbjct: 3606 IKSCKPDFFACVNETTSQISKCIPKEFYCDGEDDCPNGQDEP----DTCFGIGECTHEQF 3661
Query: 11518 RCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDG 11697
+CA SGKCIP+R CD DC D SDE + C + D +C+P ++CDG
Sbjct: 3662 QCA-SGKCIPKRRKCDGTIDCRDGSDE---------KGCKKECAIVCDNECVPVEELCDG 3711
Query: 11698 TIQCSDGLDESQ--CTLRRCL-------------PGHRQCDDGT---------CIAEHK- 11802
+C+ G DE + C +++ + G C+DG C +
Sbjct: 3712 KRKCTHGTDEEEEACAIKKLMEKPVLRTCGGFKCDGIIDCEDGADEKGCPDLECHLSNNA 3771
Query: 11803 --WCDRKKDCPNAADELHCEDVSRRTCSPFEFECANSVCIPRKFMXXXXXXXXXXSDETS 11976
CD K DC + DE +C++ + +P F+C+ + + DE
Sbjct: 3772 SLICDGKVDCESGKDEQNCQNYGGYS-NPL-FQCSRQT-VKEWQVCDGRWDCADGLDEYP 3828
Query: 11977 SECRSAQCDPPLRFRCAHSRLCLNI-LQLCNGFNDCGPNDFSDEHLSMCSSFSEYGDCSS 12153
C+S Q C + CL++ LC+GF DC +D SDE + C D
Sbjct: 3829 EMCKSRQARCFRIGFCDDKKQCLDVSTALCDGFKDC--SDGSDESPAHCK------DMCK 3880
Query: 12154 DQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKHIC-TDVRD 12330
F+C NG+C++ + CD +DDCGD SDE C C FG C C
Sbjct: 3881 GMFRCTNGRCLDESARCDGRDDCGDGSDEDTCG-----LQCHHFGT---CPQKCWMAYNS 3932
Query: 12331 GFYCHCRDGF 12360
CHC G+
Sbjct: 3933 TARCHCDVGY 3942
Score = 824 bits (2129), Expect = 0.0
Identities = 1003/4387 (22%), Positives = 1648/4387 (36%), Gaps = 350/4387 (7%)
Frame = +1
Query: 1552 DIALDPLRGEMFFTNQLKLEAAAMD---GTNRRTLVNTHTHQVSGIVVDITAKRVYWVDP 1722
D+ D + G+ F T+ + + R + T + +D K +Y+VD
Sbjct: 390 DVQYDGVNGQFFVTDSDYFQQGIWRIDVASGERNRLTTQPITSPALAIDPFTKTLYYVDS 449
Query: 1723 KVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFGS--DT 1896
+ +++IDY N RIV G + T+L + + F + D
Sbjct: 450 SANSIKAIDYNSNFSRIVVSGRIA----------------KEVTQLDYAEGKLFATLRDN 493
Query: 1897 KLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKI--------------ENPCTNADC 2034
++ +N + + + + P G + M++ N C A C
Sbjct: 494 RVFVANALESDSEAVLKTWQEITPPSNGGPNKVIMEVFHFRRNANAWKNKGRNICKAASC 553
Query: 2035 EGMCILSKDNGGFGVGYKCACPIGQKLVNGKRCIDSIDY--------LLFSSNKIVRGIF 2190
+ +CI G + C C G L+ + ID L+ + + R
Sbjct: 554 DDICI-----GHIEKTFSCLCRDG--LIQKENKCQEIDQNELKDKEILILAQLRPARVKV 606
Query: 2191 PEINEKALAEAV-LPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAA 2367
N+ E + +P ++R + F D G D+ +++ + D
Sbjct: 607 LGFNKDYQTEDIGIPDILAAKRPSAITF----DPKGKRILMYDLKRHSLVVQKMDQSNTT 662
Query: 2368 PVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRDP 2547
+T M++D+ S LY D R + V ++ + +++ R + +P
Sbjct: 663 FHGLTGIMNCEGMAYDYTSDNLYMTDQKRKLITVQRLSNLSV---QKIIVRG---NMSNP 716
Query: 2548 VSVVVHPWKGLLFYA--------EAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFA 2703
++ VH K LF+ +A PA I R +DG + + + + + +D
Sbjct: 717 RAIAVHVAKSYLFWGSWSEDRQNDATTPAMIERSKLDGSERKTLVSKNSMWINGLTLDLK 776
Query: 2704 ENRLCWGDTLLKTISCMDFDG--KNVVKLDIDN-PIPVAITIMNEYIYYVHQRPYSIRRV 2874
+ L W D I + ++G + V+ +D P + + +I++ + +++RV
Sbjct: 777 NDFLYWCDAYRNVIERIRWNGADREVIIQGVDKISHPYGLAFFDNHIFFTEFKRGAVKRV 836
Query: 2875 HKKNGGGSKIVREFGAD--ERSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSE 3048
+ + + ++ A E ++F + S P S S C CFAT +
Sbjct: 837 NVNFPDQVQEIFQYSATVFELAVFK-NSLSKSTSPCSTSS-------SNCEHFCFATSCK 888
Query: 3049 SHPNELEAKCACRQGFMINKENNHSCQKDPAEKIEQLCSSNSTQFQCKNGR-CIPKEWKC 3225
KC C G + +N C KD + C + +F C N R CIPK C
Sbjct: 889 GSVGCEPVKCGCADGMKL--VDNGKCVKDEHWEDPNGCDEDR-EFTCLNSRKCIPKANLC 945
Query: 3226 DGENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXV 3405
DG++DC D SDE D G + +C N +C +T CIP +
Sbjct: 946 DGDDDCGDGSDE-DSNG--ICKDFKCVGNKFQCDSTT-CIPLEFLCDGKSDCNDGTDELE 1001
Query: 3406 KYCKDGQKPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNATCAANQFSCA 3585
CK C+ +F+C N +CI + + E+ + + C +F C
Sbjct: 1002 TMCKTVPDVRCSVGQFRCSNTKCIDKSKRCNGIQDCENGSDEE-DCPRSKLCTPTEFRCG 1060
Query: 3586 NGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQ-CVPLR---NHXXXX 3753
G CI +CDG C DG DE QFRCAN + C+ + +
Sbjct: 1061 TGLCIKQSQVCDGKMQCLDGLDEKHCEENNSCIKGRQFRCANKQSTCLDMIFQCDGVPDC 1120
Query: 3754 XXXXXXXXXXXXAVTAESCTP-DQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSG 3930
T+ SC +QF C + G C+ + DE + C
Sbjct: 1121 EDESDESPEFCKGNTSSSCAKMNQFMC-ADGKCLRSFQLCDGFPDCLTGEDEKE--CPPS 1177
Query: 3931 RQCSSDQFKCGNG-RCILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACEND 4107
S+ C NG +C+ CDG +DCGD SDES + +C C++
Sbjct: 1178 MCNSATHLSCANGNKCVSKELECDGVDDCGDKSDESHCDDIRMEAALLRCIPPMYKCQSG 1237
Query: 4108 QETCIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCSFKCHNSPNGPICSCPFGEQL 4287
+ CI QLCDGK CP G DEG C+ LC++ GCS C +P+GPICSCP E
Sbjct: 1238 RFQCISDKQLCDGKNDCPSGDDEGMWCSF-LCNSTEIGCSHTCRATPSGPICSCP-DEYF 1295
Query: 4288 VNK--TKCEPENECLDSSSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIY 4461
+ K C ++ C CSQ C + C C++GY+L D+ +C+ D + IY
Sbjct: 1296 LEKDGVTCAKKDPCR-FGQCSQHCMSQGSRHFCYCEDGYKLLNDRISCRTVDPKTEFMIY 1354
Query: 4462 VSNRNRIYYSDHKLDNWHTFGAIVENAIALAWDSLTDR---IYWSDIREKKILSA---NR 4623
SNR+ I + + NAIAL + L + +YW+D+ KI S R
Sbjct: 1355 -SNRHEIRMIQATSPGSIPLISSLTNAIALDFKYLNNGSLIVYWTDLSSDKIYSGLMDQR 1413
Query: 4624 NGTNATVFIADGLDITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQP 4803
+ ++ G+ EGIA+DW+ N+YW+DS L+TI+V + ED +R +V++N+
Sbjct: 1414 TIMYSRTIVSYGVFNAEGIAVDWITGNIYWIDSHLDTIQVLS-EDGTKRATVVNENMGNA 1472
Query: 4804 RGIAVDPRKGVMFWTDWGQ-NPCIERASMDGTDRQIIVK----TKIYWPNTIALDYTTDR 4968
R +A+D +G+MFWTDW + NP IER ++ G +R + K + WPN IALD T R
Sbjct: 1473 RSLAIDVEEGLMFWTDWEEANPRIERCTLAGKNRATVWKISNVAQAGWPNGIALDTITKR 1532
Query: 4969 VYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKY 5148
VY+ D+K D I + YDG VL + + H + ++ D +Y+SD R + K+
Sbjct: 1533 VYWVDAKSDSIHTITYDGRDHVLVLRDPERLGHCFGIDVYGDNVYFSDWRTNTISTVNKF 1592
Query: 5149 PNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTNPCSHLCLLNNKNTFTCKCPMGE 5328
G + ++ + VH Q N C C+ +CL + +N +C+C +
Sbjct: 1593 GKGEVT-IVERVATQPFSLKIVHRSKQKRQLKNMCDGFKCNGICLNDGRNKASCQCTNIQ 1651
Query: 5329 KLDASGKKCIDDAKPFLVIIQKTNVFGIEMNSASEKETPVLAGMVPLSGLGNAFDAAYD- 5505
G C+D + L+I K V G P+++G F+ D
Sbjct: 1652 TTTDDG--CVD-VEQTLLIATKNAVRGFSTIPPHPHAFPLVSG--------KQFENIRDV 1700
Query: 5506 -ALSEEMFILEHTNHAKTLAQIT--TDSAIYRSTVNGGNKTKMFSSAVPDDAYCLGFDWN 5676
+ + IL+ L +T D I + + + M V + Y F +
Sbjct: 1701 GSFQNRLQILDDLTDQVVLVNLTGEADEQILATGSDMYGVSGMTIDPVLGNTYFTFFSND 1760
Query: 5677 GRNLVVGNKITQTIEIIRTQGKQYRSVILSNDQSXXXXXXXXXXXXXXXKGYVFWLDRGG 5856
G T IE+I +G + ++ S K ++W + G
Sbjct: 1761 G---------TGRIEVINAEGTSKKVLVESGTFPGMRFPRGIIFVNSTKK--LYWFEAGT 1809
Query: 5857 GAADAKVARAGLDGSNPLVIASNDLAELDHIAIDTTNTRVYF-SEAKAGR-------ISS 6012
A +G+ L + S L ++ + +D N+++Y+ S+ K + I+
Sbjct: 1810 TPYTIFTMSAAGNGAKKLKLNSTLLTKVYNPTVDQFNSKLYWISQGKIVQFNPATEIINE 1869
Query: 6013 VTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADS------AFDSIEVATINGDSQPPQWT 6174
+ G D++ V S Q NG G+ + A+ + + G Q P +
Sbjct: 1870 IEVTGGDKN-VSSIAVDQKNGDILIGEFVRIANQTTVRRLSMKGTKSTQTGGVMQVPLHS 1928
Query: 6175 HFKKDVENLANIKALQPRASSSGHPCHINNGNCDHICIPLMFAQRTCTCANGYVKDGQTS 6354
+ + + K ++ + C C+ +C+ C C+ GY+ +
Sbjct: 1929 SVQFFLATIDTSKVVK----NIPDECK----TCESLCLSKDQKTFECACSQGYILENG-K 1979
Query: 6355 CKLFDESFVIVATKTKV--IGYPIDETQSKGVAM-------EPIGGLSITGVDYDYESKT 6507
C+ ++ + V V +G+ D+ + V + IG I + D +
Sbjct: 1980 CRSPEKRVIYVTDDGSVQSVGWYKDQKSGEMVQVMRAHSLHSDIGKKRIVRLVADTKKDV 2039
Query: 6508 IYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINYNMYFINHDAERTNI 6687
IYV + + + + A + S S I ++++D + ++ ++ +
Sbjct: 2040 IYV-----VTRQNEVWKCATNGSFAHMIYSTTSHRIAAISLDRVTGHLLVSARESVSSKG 2094
Query: 6688 EVSKLD------GTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQRSFLDGSRR 6849
++ LD G Y +++ + + P IAVDP ++WA I+ + DGS
Sbjct: 2095 DIVLLDPDRYQEGMY-SVIVEDEEKVPYEIAVDPPKGKIFWASAH---CIKAANYDGSEP 2150
Query: 6850 EVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPE-----LVRSDIASAAG 7014
+ IV+ + VD + + D++ + V G + +A
Sbjct: 2151 KCIVAKSAV--ATIAVDEDRSRLCYMDSERAAVDCVDYNGENEQRNVAMFKAQGLAEVVS 2208
Query: 7015 VALHGQNMYWTD--NRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRA 7188
++ +G M++ D N + R + + + + + + + + F +Q ++
Sbjct: 2209 LSFNGDEMFFFDKFNSSGSIVRGIVQKDGSVVFVDSIKKQLPRQKLR-IIDFDIMDQKKS 2267
Query: 7189 SSPCQITDNLRKSPCTQLCFATPGTQT--PTCSCARGV-LKGRTCEEPDTYIMFSDGDKI 7359
++N C LC P + C C V + TC + +T++ F+ I
Sbjct: 2268 VLFTACSNN--NGGCEHLCITVPFEDSIKKKCICVHSVPTEDGTCGQSNTFVAFTRFTSI 2325
Query: 7360 IDVAIEPDVKAS--RPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAE 7533
++ P V A + + ++ + D + R+YF ++ F
Sbjct: 2326 EFLSATPGVMAPPYKQIASASCAMTKIGAIAADNSRGRIYFADYEKFRISAVNFD----- 2380
Query: 7534 NPRLVFGASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLST------ 7695
G A+++R + M D + +++Y+ + + ID A +L
Sbjct: 2381 ------GTGCVVIAEDVRVVPSMAYDEVNRELYYVSANPAGIWRIDVADNNLENYPTEPK 2434
Query: 7696 ----IASGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESIS 7863
+ + D LAIDPC LLF++++ S IER+ +G R+ I+ E +
Sbjct: 2435 LVLLLTNRDRPRHLAIDPCRMLLFFTNNAITGSV------IERAYFSGYKREQILQEDLH 2488
Query: 7864 LPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGYRAKS-----LDIWDRWLYM 8028
+A+D +K+Y++D I D DG NR+V+ S S L+I++ +
Sbjct: 2489 DLRGLAIDLETEKLYFSDSKDFRISRCDLDGCNREVVISNSDNPSIHPFELEIYENEIIF 2548
Query: 8029 SDPLSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDN 8208
+D + V I+K SG + +P L V + T+N C +
Sbjct: 2549 TDWVKRAVSGINKISGVEHRLMNRATEVPVGLVVVDVSKEFCTKNP---------CYENE 2599
Query: 8209 GGCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSEPAKECLPPY 8388
C C ++AD + C+CN L
Sbjct: 2600 LKCGDYCRLMAD------GQATCACNGERRL----------------------------- 2624
Query: 8389 NFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNR-RCIDSAKKCNH 8565
+ D+K D + + C E+ C + +CI C+
Sbjct: 2625 --------------SADNKTCTGDVDE--------KKCAENEFKCLHSDKCIPYEDTCDQ 2662
Query: 8566 IDDCG--DGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCP 8739
+DC D D C S V C G F C NG CI+++KVC+ NDC + DE+ TC
Sbjct: 2663 YNDCPMFDDEDAKYCSSRV-CRPGYFDCGNGLCISESKVCNRFNDCIN--FHDENNCTCS 2719
Query: 8740 GLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQ-------HYV 8898
C ++ CI D C+ DC D +DE + C + C+ +
Sbjct: 2720 KSEFKC--------DSGNCIPGEDRCNHVQDCNDASDE--IGCPYRNCSSLVEFGMSDLI 2769
Query: 8899 RCPS-GRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFI 9075
C S +CI +W+CDG NDC DG DE C+ ++ F ++
Sbjct: 2770 NCASTSQCIHPSWKCDGTNDCYDGSDELD-----------CLVEFDFNKGSVS------- 2811
Query: 9076 XXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGG 9255
C + T +F C + C+P W CDG CA G
Sbjct: 2812 --------------PPRSCDSAT----QFPCLATRN-------CMPNRWRCDGQPDCADG 2846
Query: 9256 EDESTELCKTEKKECNKGEFRC-SNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQP-- 9426
DE+ E+K CN EF C S + CI +CDG +DC +G DE++ T +
Sbjct: 2847 SDEAN----CEQKACNSFEFTCESTKKCIPLEQKCDGRSDCPNGEDENSCDTECDSKNGN 2902
Query: 9427 DFFQCANHKCVPNSWKCDGNDDCED-----GSDEKDCPKNSASAQKASKCSN-------- 9567
F+C NH+C+P +W+CDG DDC D GSDE DC S S+C++
Sbjct: 2903 STFRCTNHRCIPMAWRCDGTDDCLDNAKSLGSDEMDCAPGKTSFHVPSRCTDETCVVACE 2962
Query: 9568 ------------------------------GQFQCTSGECIDDAKVCDRNFDCTDRSDES 9657
++ C SG+CI+ A +CD + DC D SDE
Sbjct: 2963 LTAVLCDGIKDCNDGFDEENCASLDRQCKLNEWMCDSGQCINSAHLCDSSVDCIDGSDE- 3021
Query: 9658 SLCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNECYEGI----- 9822
+++ CSL+E P ++ C + G+ C G + + + C +C GI
Sbjct: 3022 ---WVEICSLSEPP--KRGCPN---GWSCVLKNGTIGCLQEHQLCDGRKDCMSGIDEQCD 3073
Query: 9823 ----------SGCSQ--KCDDKIGSYKCGCVDGYQLSS-DDHSCKRTEMEPEPFFLLANK 9963
+ C Q C G C C +G+ LS D +C R+ P+ AN
Sbjct: 3074 LPQGNCSSARNSCEQPWNCKRNAGFETCSCDEGFHLSPYDKRTCLRSPSCPK-----ANC 3128
Query: 9964 HYIRKISIDGNKYELAAQGF---DNVVSLDI-DLTEKKAYLIDQGKLRLLRVDLDEMDSP 10131
+ D A GF DN D E + ++ +L+L +D +
Sbjct: 3129 SHFCIDRRDVGHQCFCAPGFILSDNQRDCRRNDTIEPEILMVSGHRLKLFTIDGHAKATL 3188
Query: 10132 LSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKA 10311
LS+ T G+A+D+ +S V D
Sbjct: 3189 LSNL----------TNGVALDY----------DVKSDLVYWTD----------------- 3211
Query: 10312 IVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLF 10491
V + G T S QPY RI I L + + IA+D+ ++
Sbjct: 3212 -VTNSGNK-AGITSMSNQPYTYRI-----------INSLPTKGI---DGIAVDWLGRHIY 3255
Query: 10492 WGDAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDY---LYWADWNLREVLRCDKWT 10662
+ D + + I D G R + + +V D L+W DW +
Sbjct: 3256 YTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPIQALLFWTDWGASAHIGRMNMD 3315
Query: 10663 GKNETIL--KKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGCSH------LCLIGAGGNGY 10818
G NE I+ +T++ PN L + P ++ + + D C++ + L + + +
Sbjct: 3316 GSNEMIILEDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGTKRRMVLRNSVRHIF 3375
Query: 10819 TCSCPDQFVLLSDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEP-GESI 10995
+ + ++ SD + ER GD+ K + +D P G +
Sbjct: 3376 ALAVFEDYIYWSDWHN---HTIERVHKITGDNRKVL-----------IQDKQYRPMGFKV 3421
Query: 10996 CGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXXEQNCDKACDPWMFKCAATGRCIPR 11175
+G + H C++P + CD C P
Sbjct: 3422 VHPSFQNMGSMKTAKHPCSQPAR----------------CDNLCIP-------------- 3451
Query: 11176 RFTXXXXXXXXXRSDEADTLCMSAERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXET 11355
S EA T CM A+ FR + C++
Sbjct: 3452 -----------ASSPEAFT-CMCAQG------FRSDGRSCVS------------------ 3475
Query: 11356 PECAQIECKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDED---KQRCPTCD-DVGEFRC 11523
ECK C+ +Y+CI +W C+GQDDC D DE K CP D G+F C
Sbjct: 3476 ------ECKPNDFVCTKTYKCIASWWRCDGQDDCGDGEDEGYFLKGVCPQFPCDPGQFLC 3529
Query: 11524 A-----TSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGK-CIPGSK 11685
T+ +C+ +CD DC + DE C C+ES+F+C D K CIP +
Sbjct: 3530 PKSPRNTTAQCLYASKLCDGVKDCLEGEDEEKTFCEHFE--CTESQFKCGDKKKCIPLTS 3587
Query: 11686 VCDGTIQCSDGLDESQCTLRRCLPGHRQCDDGT------CIAEHKWCDRKKDCPNAADEL 11847
VCD C DG DE C ++ C P C + T CI + +CD + DCPN DE
Sbjct: 3588 VCDKEKDCDDGSDERSCEIKSCKPDFFACVNETTSQISKCIPKEFYCDGEDDCPNGQDEP 3647
Query: 11848 H-CEDVSRRTCSPFEFECANSVCIPRKFMXXXXXXXXXXSDETS--SECRSAQCDP---P 12009
C + C+ +F+CA+ CIP++ SDE EC + CD P
Sbjct: 3648 DTCFGIGE--CTHEQFQCASGKCIPKRRKCDGTIDCRDGSDEKGCKKEC-AIVCDNECVP 3704
Query: 12010 LRFRCAHSRLCLN------------------ILQLCNGFN-----DCGPNDFSDE----- 12105
+ C R C + +L+ C GF DC D +DE
Sbjct: 3705 VEELCDGKRKCTHGTDEEEEACAIKKLMEKPVLRTCGGFKCDGIIDC--EDGADEKGCPD 3762
Query: 12106 ---HLSMCSSFSEYG--DCSS--DQFKCANG--------KCVNGTV----ACDRKDDCGD 12228
HLS +S G DC S D+ C N +C TV CD + DC D
Sbjct: 3763 LECHLSNNASLICDGKVDCESGKDEQNCQNYGGYSNPLFQCSRQTVKEWQVCDGRWDCAD 3822
Query: 12229 ASDEIGCSKHGGKTSCEAFG---NNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKE---- 12387
DE + C G + C + T + DGF C DG P K+
Sbjct: 3823 GLDEYPEMCKSRQARCFRIGFCDDKKQCLDVSTALCDGFK-DCSDGSDESPAHCKDMCKG 3881
Query: 12388 --------CIDI-------DECAGNN-------------TCTQLCLNTKGSYLCRCHEDY 12483
C+D D+C + TC Q C S RCH D
Sbjct: 3882 MFRCTNGRCLDESARCDGRDDCGDGSDEDTCGLQCHHFGTCPQKCWMAYNS-TARCHCDV 3940
Query: 12484 ENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXX 12663
S DC + + L + +
Sbjct: 3941 G---YTKSTKYNDCEPLTKFTEIFLSNGKRLHLMVAEETRLRTVFNERMNIISGGIDFGY 3997
Query: 12664 XXPRKELMYWID-GSERTIYRSAIANGNQSHE--GQKLDVDFAAMGVVPTAIAVDYTTGN 12834
+ LMY + G R R+ + ++ + G+K D A + IA D+ N
Sbjct: 3998 DMYKTTLMYSVGIGKNRVDIRTKKWSESKPSDEWGEKNDESTAGL------IAHDFMHNN 4051
Query: 12835 LFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALIT 13014
+++ I L ++ I+V + ++ T+L
Sbjct: 4052 VYLTESGSYIPGILFHTQEN-------------IYVAKSKDTNTRTLIVNSTGSITSLSV 4098
Query: 13015 APSAGRICYSDAGLHAKIECADMDGT------------HRQIIVKDLVFSPTSMAIDEGK 13158
P I ++ +I A +DGT H+ +I ++ +F P S+ +D
Sbjct: 4099 DPIQRLIFWTTGAPVPRILSAHLDGTPIAQLFKTGSQPHKALIERN-IFDPKSLILDS-P 4156
Query: 13159 GNRIYWVDPKYRRVDAVNIDGSERTTV--VHDRHIPYAVDVFENHIYWLSRESKTLYVQD 13332
R+YW+D R V+ V+ DG +R TV P ++D+ +IY ++ + ++
Sbjct: 4157 NKRLYWIDGFKRTVETVSYDGRDRRTVRKFELGDSPVSMDIIGGYIYLVTLQG-NIHKMH 4215
Query: 13333 KFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVS-------GCERAQCSHLCVSLPSTG 13491
KF G+ + + D R+ A ++ TVS C+ C V +P
Sbjct: 4216 KFS-GKTNKYPQRIRD-VAPRIRLLIAHPSKHTVSHITHQKNPCQSDYCPSETVCIPKED 4273
Query: 13492 F------ACLCPDG-IVPQLDGSCATQHVEALTMPKQCK---CTNGGKCRLDGSCECTSD 13641
CLC G + C H + QC C N C C C
Sbjct: 4274 TNGVLIPKCLCGAGRFFEESTKKCLPVH-DMNQEASQCGDYFCYNNAACSAQKKCICPPG 4332
Query: 13642 FEGDQCE 13662
F G QCE
Sbjct: 4333 FYGRQCE 4339
Score = 278 bits (710), Expect = 4e-72
Identities = 261/1055 (24%), Positives = 420/1055 (39%), Gaps = 47/1055 (4%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPG-CKSDQWQCDTYTWHSVSCIA 333
C+ FRC++ KCI P C +++C T CI
Sbjct: 1012 CSVGQFRCSNTKCIDKSKRCNGIQDCENGSDEEDCPRSKLCTPTEFRCGTGL-----CIK 1066
Query: 334 EYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQ-CFDVSKKCDGKYDCRDLSD 510
+ Q CD C DG DEK C + C F CA+ + C D+ +CDG DC D SD
Sbjct: 1067 QSQVCDGKMQCLDGLDEKHCEENN-SCIKGRQFRCANKQSTCLDMIFQCDGVPDCEDESD 1125
Query: 511 EKDSCSRNHTA--CFQY-QFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKC-TAN 678
E + +T+ C + QF CAD +C++ +CDG DC G DE + C C +A
Sbjct: 1126 ESPEFCKGNTSSSCAKMNQFMCADG-KCLRSFQLCDGFPDCLTGEDEKE-CPPSMCNSAT 1183
Query: 679 EFQCKN-KRCQPRKFRCDYYDDCGDNSDEDECGEYR-------CPPGKWNCP-GTGHCID 831
C N +C ++ CD DDCGD SDE C + R C P + C G CI
Sbjct: 1184 HLSCANGNKCVSKELECDGVDDCGDKSDESHCDDIRMEAALLRCIPPMYKCQSGRFQCIS 1243
Query: 832 QLKLCDGSKDCADGADEQQCSQNLCPS--LGCQAGCHPSPHGGECTCPSGYKLDDRFHRT 1005
+LCDG DC G DE LC S +GC C +P G C+CP Y L+ + T
Sbjct: 1244 DKQLCDGKNDCPSGDDEGMWCSFLCNSTEIGCSHTCRATPSGPICSCPDEYFLE-KDGVT 1302
Query: 1006 CSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKM 1185
C+ + C FG C Q C + C C G L R C + +
Sbjct: 1303 CAKKDPC-RFGQCSQHCMSQGSRHFCYC-----------EDGYKLLNDRISCRTVDPKTE 1350
Query: 1186 KLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDY---GDRKIFWTDRLAHSAFSAD 1356
+ + R + + +P + ++S +DF Y G ++WTD + +S
Sbjct: 1351 FMIYSNRHEIRMIQATSPGS-IPLISSLTNAIALDFKYLNNGSLIVYWTDLSSDKIYSG- 1408
Query: 1357 VDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADG 1536
+ D+ I + + + +AVDWIT +Y I+S I V S DG +R ++ +
Sbjct: 1409 LMDQRTIMYSRTIVSYGVFNAEGIAVDWITGNIYWIDSHLDTIQVLSEDGTKRATVVNEN 1468
Query: 1537 LTLPLDIALDPLRGEMFFTN----QLKLEAAAMDGTNRRTLVN----THTHQVSGIVVDI 1692
+ +A+D G MF+T+ ++E + G NR T+ +GI +D
Sbjct: 1469 MGNARSLAIDVEEGLMFWTDWEEANPRIERCTLAGKNRATVWKISNVAQAGWPNGIALDT 1528
Query: 1693 TAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQ 1872
KRVYWVD K D + +I Y G D +V + + H FG+ ++ +Y++DW +
Sbjct: 1529 ITKRVYWVDAKSDSIHTITYDGRDHVLVLRDPERLGHCFGIDVYGDNVYFSDWRTNTIST 1588
Query: 1873 VEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCIL 2052
V KFG + P + H Q +++N C C G+C+
Sbjct: 1589 VNKFGKGEVTIVERVATQ--PFSLKIVHRSKQ---------KRQLKNMCDGFKCNGICLN 1637
Query: 2053 SKDNGGFGVGYKCACPIGQKLVNGKRCIDSIDYLLFSSNKIVRGIFPEINEKALAEAVLP 2232
N C C Q + C+D LL ++ VRG + +P
Sbjct: 1638 DGRNKA-----SCQCTNIQTTTD-DGCVDVEQTLLIATKNAVRGF-----------STIP 1680
Query: 2233 ISPISQRRI-GMYFEVECDVHG--NSFFYADIMDNTIYRIRPDGEGAAPVLVTHND--GL 2397
P + + G FE DV N D + + + + GE +L T +D G+
Sbjct: 1681 PHPHAFPLVSGKQFENIRDVGSFQNRLQILDDLTDQVVLVNLTGEADEQILATGSDMYGV 1740
Query: 2398 FSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVV-VHPWK 2574
M+ D + Y+ + +++ LV +R P ++ V+ K
Sbjct: 1741 SGMTIDPVLGNTYFTFFSNDGTGRIEVINAEGTSKKVLVESGTFPGMRFPRGIIFVNSTK 1800
Query: 2575 GLLFYAEAMRPAAIYRCHIDGQNCQVIR--NTTLGRPSEMAIDFAENRLCW--------- 2721
L ++ P I+ G + ++ +T L + +D ++L W
Sbjct: 1801 KLYWFEAGTTPYTIFTMSAAGNGAKKLKLNSTLLTKVYNPTVDQFNSKLYWISQGKIVQF 1860
Query: 2722 --GDTLLKTISCMDFDGKNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGG 2895
++ I D KNV + +D ++ E++ +Q ++RR+ K G
Sbjct: 1861 NPATEIINEIEVTGGD-KNVSSIAVDQ--KNGDILIGEFVRIANQT--TVRRLSMK---G 1912
Query: 2896 SKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAK 3075
+K + G + + S + P C LC + ++ +
Sbjct: 1913 TKSTQTGGVMQVPLHSSVQFFLATIDTSKVVKNIPDECKTCESLCLSKDQKTF------E 1966
Query: 3076 CACRQGFMINKENNHSCQKDPAEKIEQLCSSNSTQ 3180
CAC QG+++ N C + P +++ + S Q
Sbjct: 1967 CACSQGYIL---ENGKC-RSPEKRVIYVTDDGSVQ 1997
Score = 262 bits (670), Expect = 2e-67
Identities = 325/1401 (23%), Positives = 518/1401 (36%), Gaps = 113/1401 (8%)
Frame = +1
Query: 9769 DISDQKSCHNVNECYEGISGCSQKC-----DDKIGSYKCGCVDGYQLSSDDHSCKRTEME 9933
DI DQK C GC C +D I KC CV + + ++D +C ++
Sbjct: 2260 DIMDQKKSVLFTACSNNNGGCEHLCITVPFEDSIKK-KCICV--HSVPTEDGTCGQSNT- 2315
Query: 9934 PEPFFLLANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDL 10113
F I +S + A + + S +T+ A D + R+ D
Sbjct: 2316 ---FVAFTRFTSIEFLSATPG---VMAPPYKQIASASCAMTKIGAIAADNSRGRIYFADY 2369
Query: 10114 DEMDSPLSSYE----TVLRHNVYGTEGIAVDWVGRKLYMLNRQERSI-RVCELDGRFCK- 10275
++ +++ V+ +V +A D V R+LY ++ I R+ D
Sbjct: 2370 EKFRISAVNFDGTGCVVIAEDVRVVPSMAYDEVNRELYYVSANPAGIWRIDVADNNLENY 2429
Query: 10276 ------TLIRDRIQQPKAIVVHPGKGYLFFTEWSLQ-PYIGRIALDGSPELQDPIFKLAE 10434
L+ +P+ + + P + LFFT ++ I R G Q + +
Sbjct: 2430 PTEPKLVLLLTNRDRPRHLAIDPCRMLLFFTNNAITGSVIERAYFSGYKREQ-----ILQ 2484
Query: 10435 HDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHIPAQRTS---HVSSMVVFDD 10605
DL +AID +++L++ D+ I D DG R + + + H + ++++
Sbjct: 2485 EDLHDLRGLAIDLETEKLYFSDSKDFRISRCDLDGCNREVVISNSDNPSIHPFELEIYEN 2544
Query: 10606 YLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGCSH 10785
+ + DW R V +K +G ++ + ++P L +V ++ NPC +N
Sbjct: 2545 EIIFTDWVKRAVSGINKISGVEHRLMNRATEVPVGLVVVDVSKEFCTKNPCYENE----- 2599
Query: 10786 LCLIGAGGNGYTCSCPDQFVLLSD-QKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDC 10962
C D L++D Q TC N R A D K C G+ D
Sbjct: 2600 ------------LKCGDYCRLMADGQATCACNGERRLSA----DNKT------CTGDVD- 2636
Query: 10963 RDGSDEPGESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXXEQNCDKACDPWMF 11142
++ C EF+C + + P+ E CD+ D MF
Sbjct: 2637 -------------EKKCAENEFKCLHSDKCIPY--------------EDTCDQYNDCPMF 2669
Query: 11143 KCAATGRCIPRRFTXXXXXXXXXRSDEADTLCMSAERNCTAEEFRCNNNKCIAKAWRXXX 11322
DE C S R C F C N CI+++ +
Sbjct: 2670 ------------------------DDEDAKYCSS--RVCRPGYFDCGNGLCISES-KVCN 2702
Query: 11323 XXXXXXXXXETPECAQIECKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCD 11502
+ C C K +C S CIP CN DC D SDE C
Sbjct: 2703 RFNDCINFHDENNCT---CSKSEFKCDSG-NCIPGEDRCNHVQDCNDASDEIGCPYRNCS 2758
Query: 11503 DVGEF------RCATSGKCIPRRWMCDTENDCGDNSDELDA------SCGGTTRP--C-S 11637
+ EF CA++ +CI W CD NDC D SDELD + G + P C S
Sbjct: 2759 SLVEFGMSDLINCASTSQCIHPSWKCDGTNDCYDGSDELDCLVEFDFNKGSVSPPRSCDS 2818
Query: 11638 ESEFRCNDGK-CIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQCDDGT-CIAEHKWCD 11811
++F C + C+P CDG C+DG DE+ C + C C+ CI + CD
Sbjct: 2819 ATQFPCLATRNCMPNRWRCDGQPDCADGSDEANCEQKACNSFEFTCESTKKCIPLEQKCD 2878
Query: 11812 RKKDCPNAADELHCEDVSRRTCSPFEFECANSVCIPRKFMXXXXXXXXXXSDETSSE--- 11982
+ DCPN DE C+ F C N CIP + + S+
Sbjct: 2879 GRSDCPNGEDENSCDTECDSKNGNSTFRCTNHRCIPMAWRCDGTDDCLDNAKSLGSDEMD 2938
Query: 11983 CRSAQCDPPLRFRCAHSRL---CLNILQLCNGFNDCGPNDFSDEHLSMCSSFSEYGDCSS 12153
C + + RC C LC+G DC ND DE C+S C
Sbjct: 2939 CAPGKTSFHVPSRCTDETCVVACELTAVLCDGIKDC--NDGFDEE--NCASLDR--QCKL 2992
Query: 12154 DQFKCANGKCVNGTVACDRKDDCGDASDE---------------------------IGCS 12252
+++ C +G+C+N CD DC D SDE IGC
Sbjct: 2993 NEWMCDSGQCINSAHLCDSSVDCIDGSDEWVEICSLSEPPKRGCPNGWSCVLKNGTIGCL 3052
Query: 12253 KH----GGKTSCEAF---------GNNGGCKHICTDVRD-----GFY-CHCRDGFRPDPQ 12375
+ G+ C + GN ++ C + GF C C +GF P
Sbjct: 3053 QEHQLCDGRKDCMSGIDEQCDLPQGNCSSARNSCEQPWNCKRNAGFETCSCDEGFHLSPY 3112
Query: 12376 SPKECIDIDECAGNNTCTQLCLNTKG-SYLCRCHEDYENNVVVGSMTGKDCRAKGDAA-N 12549
+ C+ C N C+ C++ + + C C + + S +DCR
Sbjct: 3113 DKRTCLRSPSCPKAN-CSHFCIDRRDVGHQCFCAPGF-----ILSDNQRDCRRNDTIEPE 3166
Query: 12550 VMIGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERTIYRSA 12729
+++ + L ++ G H + +L+YW D +
Sbjct: 3167 ILMVSGHRLKLFTIDG-----HAKATLLSNLTNGVALDYDVKSDLVYWTDVTNSGNKAGI 3221
Query: 12730 IANGNQSHEGQKLDVDFAAMGVVPT----AIAVDYTTGNLFIAAVSENIENGLVTARKKR 12897
+ NQ + + + +PT IAVD+ +++
Sbjct: 3222 TSMSNQPYT-------YRIINSLPTKGIDGIAVDWLGRHIYYT----------------- 3257
Query: 12898 MSEPIDNQNTGFIFVCLPDGRYLKKIVAGH-LQQPTALITAPSAGRICYSDAGLHAKIEC 13074
++N I VC GR+ + ++ G L P A++ P + ++D G A I
Sbjct: 3258 ------DRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPIQALLFWTDWGASAHIGR 3311
Query: 13075 ADMDGTHRQIIVKDLVFS-PTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHD- 13248
+MDG++ II++D P ++A+D R+Y+ D + + N DG++R V+ +
Sbjct: 3312 MNMDGSNEMIILEDRTIRWPNALAVD-APAQRLYFGDAHRDYIASCNYDGTKRRMVLRNS 3370
Query: 13249 -RHIPYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLE----DGHTVRVSQKYA 13413
RHI +A+ VFE++IYW + T+ K VL D + V S +
Sbjct: 3371 VRHI-FALAVFEDYIYWSDWHNHTIERVHKITGDNRKVLIQDKQYRPMGFKVVHPSFQNM 3429
Query: 13414 KDTQRTVSGCER-AQCSHLCVSLPS-TGFACLCPDGIVPQLDG-SCATQHVEALTMPKQC 13584
+ C + A+C +LC+ S F C+C G + DG SC ++ P
Sbjct: 3430 GSMKTAKHPCSQPARCDNLCIPASSPEAFTCMCAQGF--RSDGRSCVSE-----CKPNDF 3482
Query: 13585 KCTNGGKC-----RLDGSCEC 13632
CT KC R DG +C
Sbjct: 3483 VCTKTYKCIASWWRCDGQDDC 3503
Score = 236 bits (603), Expect = 9e-60
Identities = 303/1273 (23%), Positives = 485/1273 (37%), Gaps = 159/1273 (12%)
Frame = +1
Query: 2017 CTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGKRCI---DSID--YLLFSSNKIVR 2181
C A+C CI +D VG++C C G L + +R D+I+ L+ S +++
Sbjct: 3123 CPKANCSHFCIDRRD-----VGHQCFCAPGFILSDNQRDCRRNDTIEPEILMVSGHRLKL 3177
Query: 2182 GIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDN------TIYRI 2343
A+A L +S G+ ++ DV + ++ D+ ++ T
Sbjct: 3178 -----FTIDGHAKATL----LSNLTNGV--ALDYDVKSDLVYWTDVTNSGNKAGITSMSN 3226
Query: 2344 RPDGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQ 2523
+P L T G+ ++ DW+ + +YY D +++ V + R
Sbjct: 3227 QPYTYRIINSLPTK--GIDGIAVDWLGRHIYYTDRNHDAIAVCDMRGR--------FNRI 3276
Query: 2524 LI--TELRDPVSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVI-RNTTLGRPSEMAI 2694
L+ T L DP ++V+ P + LLF+ + A I R ++DG N +I + T+ P+ +A+
Sbjct: 3277 LLKGTPLNDPRAIVLDPIQALLFWTDWGASAHIGRMNMDGSNEMIILEDRTIRWPNALAV 3336
Query: 2695 DFAENRLCWGDTLLKTISCMDFDGKNVVKLDIDNPIP--VAITIMNEYIYYVHQRPYSIR 2868
D RL +GD I+ ++DG ++ + N + A+ + +YIY+ ++I
Sbjct: 3337 DAPAQRLYFGDAHRDYIASCNYDGTKR-RMVLRNSVRHIFALAVFEDYIYWSDWHNHTIE 3395
Query: 2869 RVHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPC-RASQCTQLCFATPS 3045
RVHK G K++ + F + S QN ++ HPC + ++C LC S
Sbjct: 3396 RVHKITGDNRKVLIQDKQYRPMGFKVVHPSFQNMGSMKTAK-HPCSQPARCDNLCIPASS 3454
Query: 3046 ESHPNELEAKCACRQGFMINKENNHSCQKDPAEKIEQLCSSNSTQFQC-KNGRCIPKEWK 3222
C C QGF + + SC + C N F C K +CI W+
Sbjct: 3455 PE-----AFTCMCAQGF---RSDGRSCVSE--------CKPND--FVCTKTYKCIASWWR 3496
Query: 3223 CDGENDCLDESDE----------------------------------------------- 3261
CDG++DC D DE
Sbjct: 3497 CDGQDDCGDGEDEGYFLKGVCPQFPCDPGQFLCPKSPRNTTAQCLYASKLCDGVKDCLEG 3556
Query: 3262 IDEKGDKCFHETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQKP--- 3432
DE+ C H EC E+ KC + KKCIP K C DG
Sbjct: 3557 EDEEKTFCEH-FECTESQFKCGDKKKCIPLTSVCDKE-----------KDCDDGSDERSC 3604
Query: 3433 ---VCAAKKFQCDNH------RCIPEQWKXXXXXXXXXXXXEKLEMCGNATCAANQFSCA 3585
C F C N +CIP+++ E G C QF CA
Sbjct: 3605 EIKSCKPDFFACVNETTSQISKCIPKEFYCDGEDDCPNGQDEPDTCFGIGECTHEQFQCA 3664
Query: 3586 NGRCIPIYWLCDGDNDCYDGTDED--KERCPPV---QCSALQFRCANGRQCVPLRNHXXX 3750
+G+CIP CDG DC DG+DE K+ C V +C ++ C R+C H
Sbjct: 3665 SGKCIPKRRKCDGTIDCRDGSDEKGCKKECAIVCDNECVPVEELCDGKRKCT----HGTD 3720
Query: 3751 XXXXXXXXXXXXXAVTAESCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSG 3930
+C FKC C + + S+ C
Sbjct: 3721 EEEEACAIKKLMEKPVLRTC--GGFKCDGIIDCEDGADEKGCPDLECHLSNNASLICDGK 3778
Query: 3931 RQCSS--DQFKCGN-----------GRCILNNW-LCDGENDCGDGSDESSERGCKTSMNA 4068
C S D+ C N R + W +CDG DC DG DE E CK+
Sbjct: 3779 VDCESGKDEQNCQNYGGYSNPLFQCSRQTVKEWQVCDGRWDCADGLDEYPEM-CKS---- 3833
Query: 4069 RKCPFEHVACENDQETCIPLHQ-LCDGKTHCPGGTDEGGRCARDLCSADRAGCSFKCHNS 4245
R+ + +D++ C+ + LCDG C G+DE +D+C F+C N
Sbjct: 3834 RQARCFRIGFCDDKKQCLDVSTALCDGFKDCSDGSDESPAHCKDMCKG-----MFRCTN- 3887
Query: 4246 PNGPICSCPFGEQLVNKTKCEPENECLDSS-------------SCSQRCKDEKHGFT-CS 4383
G L +C+ ++C D S +C Q+C + C
Sbjct: 3888 ----------GRCLDESARCDGRDDCGDGSDEDTCGLQCHHFGTCPQKCWMAYNSTARCH 3937
Query: 4384 CDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGA----IVENAIAL 4551
CD GY C+ K T I++SN R++ + T I+ I
Sbjct: 3938 CDVGYTKSTKYNDCEPL--TKFTEIFLSNGKRLHLMVAEETRLRTVFNERMNIISGGIDF 3995
Query: 4552 AWDSLTDRIYWS--------DIREKKILSANRNGTNATVFIADGLDITEG-IALDWVGRN 4704
+D + +S DIR KK + + + + T G IA D++ N
Sbjct: 3996 GYDMYKTTLMYSVGIGKNRVDIRTKKWSESKPSDE----WGEKNDESTAGLIAHDFMHNN 4051
Query: 4705 LYWVDS----------SLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDW 4854
+Y +S + I VA +D RTL+V+ S ++VDP + ++FWT
Sbjct: 4052 VYLTESGSYIPGILFHTQENIYVAKSKDTNTRTLIVNSTGSIT-SLSVDPIQRLIFWTTG 4110
Query: 4855 GQNPCIERASMDGTD-----------RQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFI 5001
P I A +DGT + +++ I+ P ++ LD R+Y+ D +
Sbjct: 4111 APVPRILSAHLDGTPIAQLFKTGSQPHKALIERNIFDPKSLILDSPNKRLYWIDGFKRTV 4170
Query: 5002 DFVNYDGSGRTQVLASSKFVQHPHALAIFEDMMYY--SDRRLQKLQVYPKYPNGTTSEYP 5175
+ V+YDG R + + + P ++ I +Y + K+ + +G T++YP
Sbjct: 4171 ETVSYDGRDR-RTVRKFELGDSPVSMDIIGGYIYLVTLQGNIHKMHKF----SGKTNKYP 4225
Query: 5176 SHTFSKA--LGVVAVHPVLQPVI----KNNPCSTN--PCSHLCL----LNNKNTFTCKCP 5319
A + ++ HP V + NPC ++ P +C+ N C C
Sbjct: 4226 QRIRDVAPRIRLLIAHPSKHTVSHITHQKNPCQSDYCPSETVCIPKEDTNGVLIPKCLCG 4285
Query: 5320 MGEKLDASGKKCI 5358
G + S KKC+
Sbjct: 4286 AGRFFEESTKKCL 4298
Score = 224 bits (571), Expect = 5e-56
Identities = 198/712 (27%), Positives = 300/712 (41%), Gaps = 44/712 (6%)
Frame = +1
Query: 133 SVNTASSVCNENDFRCNDGK-CIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYT 309
SV+ S + F C + C+ W C S ++ C++
Sbjct: 2809 SVSPPRSCDSATQFPCLATRNCMPNRWRCDGQPDCADGSDEANCEQKACNSFEFTCES-- 2866
Query: 310 WHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKY 489
+ CI Q+CD +DC +G DE C + + F C + R C ++ +CDG
Sbjct: 2867 --TKKCIPLEQKCDGRSDCPNGEDENSCDTECDSKNGNSTFRCTNHR-CIPMAWRCDGTD 2923
Query: 490 DCRDL-----SDEKDSCSRNHTACFQYQFRCADKT---QCIQKSWVCDGSKDCADGSDEP 645
DC D SDE D C+ T+ F RC D+T C + +CDG KDC DG DE
Sbjct: 2924 DCLDNAKSLGSDEMD-CAPGKTS-FHVPSRCTDETCVVACELTAVLCDGIKDCNDGFDEE 2981
Query: 646 DTCEF-KKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDE-------DECGEYRCPPGKW 801
+ ++C NE+ C + +C CD DC D SDE E + CP G W
Sbjct: 2982 NCASLDRQCKLNEWMCDSGQCINSAHLCDSSVDCIDGSDEWVEICSLSEPPKRGCPNG-W 3040
Query: 802 NCP---GTGHCIDQLKLCDGSKDCADGADEQ-QCSQNLCPSL--GCQAGCHPSPHGG--E 957
+C GT C+ + +LCDG KDC G DEQ Q C S C+ + + G
Sbjct: 3041 SCVLKNGTIGCLQEHQLCDGRKDCMSGIDEQCDLPQGNCSSARNSCEQPWNCKRNAGFET 3100
Query: 958 CTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRP-GFTCSCLGDCFTLQMEHGPGK 1134
C+C G+ L RTC C + C C + R G C C F L +
Sbjct: 3101 CSCDEGFHLSPYDKRTCLRSPSCPKAN-CSHFCIDRRDVGHQCFCAPG-FILSDNQRDCR 3158
Query: 1135 DNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKI 1314
N T+ + + ++KLF L + L +G +D+D +
Sbjct: 3159 RNDTIEPEILMVSGHRLKLFTIDGHAKATL--------LSNLTNG---VALDYDVKSDLV 3207
Query: 1315 FWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRC----------LAVDWITNTLYII 1464
+WTD V + G + I +S + Y +AVDW+ +Y
Sbjct: 3208 YWTD----------VTNSGNKAGITSMSNQPYTYRIINSLPTKGIDGIAVDWLGRHIYYT 3257
Query: 1465 ESGSRRIDVSSYDGERRTVLL-ADGLTLPLDIALDPLRGEMFFTN---QLKLEAAAMDGT 1632
+ I V G +LL L P I LDP++ +F+T+ + MDG+
Sbjct: 3258 DRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPIQALLFWTDWGASAHIGRMNMDGS 3317
Query: 1633 NRRTLVNTHTHQ-VSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPF 1809
N ++ T + + + VD A+R+Y+ D D + S +Y G RR+V + N V H F
Sbjct: 3318 NEMIILEDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGTKRRMVLR--NSVRHIF 3375
Query: 1810 GLALFDQYLYWTDWTRLGVIQVEKF-GSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQS 1986
LA+F+ Y+YW+DW + +V K G + K+L + + PMG HP Q
Sbjct: 3376 ALAVFEDYIYWSDWHNHTIERVHKITGDNRKVLIQDKQYR--PMGFKVVHPSFQ------ 3427
Query: 1987 ECLAMK-IENPCTN-ADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGKRCI 2136
+MK ++PC+ A C+ +CI + F C C G + +G+ C+
Sbjct: 3428 NMGSMKTAKHPCSQPARCDNLCIPASSPEAF----TCMCAQGFR-SDGRSCV 3474
Score = 218 bits (554), Expect = 4e-54
Identities = 199/787 (25%), Positives = 326/787 (41%), Gaps = 29/787 (3%)
Frame = +1
Query: 11269 EFRC-NNNKCIAKAWRXXXXXXXXXXXXETPE--CAQIECKKGWTRCSSSYRCIPNWAFC 11439
EF C N+ KCI KA E C +C +C S+ CIP C
Sbjct: 929 EFTCLNSRKCIPKANLCDGDDDCGDGSDEDSNGICKDFKCVGNKFQCDST-TCIPLEFLC 987
Query: 11440 NGQDDCRDNSDEDKQRCPTCDDV----GEFRCATSGKCIPRRWMCDTENDCGDNSDELDA 11607
+G+ DC D +DE + C T DV G+FRC+ + KCI + C+ DC + SDE D
Sbjct: 988 DGKSDCNDGTDELETMCKTVPDVRCSVGQFRCSNT-KCIDKSKRCNGIQDCENGSDEEDC 1046
Query: 11608 SCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTLRR-CLPGHR-QC--D 11775
++ C+ +EFRC G CI S+VCDG +QC DGLDE C C+ G + +C
Sbjct: 1047 P---RSKLCTPTEFRCGTGLCIKQSQVCDGKMQCLDGLDEKHCEENNSCIKGRQFRCANK 1103
Query: 11776 DGTCIAEHKWCDRKKDCPNAADEL--HCEDVSRRTCSPF-EFECANSVCIPRKFMXXXXX 11946
TC+ CD DC + +DE C+ + +C+ +F CA+ C+ R F
Sbjct: 1104 QSTCLDMIFQCDGVPDCEDESDESPEFCKGNTSSSCAKMNQFMCADGKCL-RSFQ-LCDG 1161
Query: 11947 XXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDE-HLSMCS 12123
+ E EC + C+ CA+ C++ C+G +DCG D SDE H
Sbjct: 1162 FPDCLTGEDEKECPPSMCNSATHLSCANGNKCVSKELECDGVDDCG--DKSDESHCDDIR 1219
Query: 12124 SFSEYGDCSSDQFKCANGK--CVNGTVACDRKDDCGDASDE-IGCSKHGGKTSCEAFGNN 12294
+ C +KC +G+ C++ CD K+DC DE + CS T
Sbjct: 1220 MEAALLRCIPPMYKCQSGRFQCISDKQLCDGKNDCPSGDDEGMWCSFLCNSTEI------ 1273
Query: 12295 GGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGSYLCRCH 12474
GC H C G C C D + + + C D C C+Q C++ + C C
Sbjct: 1274 -GCSHTCRATPSGPICSCPDEYFLE-KDGVTCAKKDPCRFGQ-CSQHCMSQGSRHFCYCE 1330
Query: 12475 EDYE--NNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGSGTNRHXXXXXXXXXXX 12648
+ Y+ N+ + CR MI ++ +++ + +
Sbjct: 1331 DGYKLLNDRI-------SCRTVDPKTEFMIYSNRHEIRM-IQATSPGSIPLISSLTNAIA 1382
Query: 12649 XXXXXXXPRKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVV-PTAIAVDYT 12825
++YW D S IY +G + GV IAVD+
Sbjct: 1383 LDFKYLNNGSLIVYWTDLSSDKIY-----SGLMDQRTIMYSRTIVSYGVFNAEGIAVDWI 1437
Query: 12826 TGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTA 13005
TGN++ I++ L T I V DG +V ++ +
Sbjct: 1438 TGNIYW------IDSHLDT-----------------IQVLSEDGTKRATVVNENMGNARS 1474
Query: 13006 LITAPSAGRICYSD-AGLHAKIECADMDGTHRQIIVKDLVFS----PTSMAIDEGKGNRI 13170
L G + ++D + +IE + G +R + K + P +A+D R+
Sbjct: 1475 LAIDVEEGLMFWTDWEEANPRIERCTLAGKNRATVWKISNVAQAGWPNGIALDT-ITKRV 1533
Query: 13171 YWVDPKYRRVDAVNIDGSERTTVVHDRH---IPYAVDVFENHIYWLSRESKTLYVQDKFG 13341
YWVD K + + DG + V+ D + +DV+ +++Y+ + T+ +KFG
Sbjct: 1534 YWVDAKSDSIHTITYDGRDHVLVLRDPERLGHCFGIDVYGDNVYFSDWRTNTISTVNKFG 1593
Query: 13342 RGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTGFACLCPDGIV 13521
+G V+++ ++++ + +K ++ + C+ +C+ +C++ +C C + I
Sbjct: 1594 KGEVTIVERVATQPFSLKIVHR-SKQKRQLKNMCDGFKCNGICLNDGRNKASCQCTN-IQ 1651
Query: 13522 PQLDGSC 13542
D C
Sbjct: 1652 TTTDDGC 1658
Score = 192 bits (488), Expect = 2e-46
Identities = 312/1289 (24%), Positives = 466/1289 (35%), Gaps = 141/1289 (10%)
Frame = +1
Query: 7609 DWLTQKIYFTTGRGGKVMAIDTAGEH--LSTIASGDWTYALAIDPCSGLLFWSDSGYKTS 7782
D + +I +G K+ ID + LS + +G AL D S L++W+D T+
Sbjct: 3161 DTIEPEILMVSGHRLKLFTIDGHAKATLLSNLTNG---VALDYDVKSDLVYWTDV---TN 3214
Query: 7783 GGLYEPRIERSNLAGGSRKVIVSESI-SLPA----AIAVDFRNQKIYWADVNRLNIEVAD 7947
G ++ + S + I SLP IAVD+ + IY+ D N I V D
Sbjct: 3215 SG------NKAGITSMSNQPYTYRIINSLPTKGIDGIAVDWLGRHIYYTDRNHDAIAVCD 3268
Query: 7948 YDGQNRKVIASGY-----RAKSLDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVSDRRI 8112
G+ +++ G RA LD L+ +D ++ GS ++ DR I
Sbjct: 3269 MRGRFNRILLKGTPLNDPRAIVLDPIQALLFWTDWGASAHIGRMNMDGSNEMIILEDRTI 3328
Query: 8113 --PGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQ---LCTVVADDIGLAASKVQC 8277
P AL V A R +A + + G + L V LA +
Sbjct: 3329 RWPNALAVDAPAQ----RLYFGDAHRDYIASCNYDGTKRRMVLRNSVRHIFALAVFEDYI 3384
Query: 8278 SCND----TYELVQEPGKDYPTQCVLRGSNSEPA--KECLPPYNFQCGDGSCILLGATCD 8439
+D T E V + + G N + + P F+ S +G+
Sbjct: 3385 YWSDWHNHTIERVHK----------ITGDNRKVLIQDKQYRPMGFKVVHPSFQNMGSMKT 3434
Query: 8440 SKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHIDDCGDG--SDELDCPSA 8613
+K C+ + N C S PE + C+ C G SD C S
Sbjct: 3435 AKHPCSQPA-RCDNLCIPASSPEAFT------CM-----------CAQGFRSDGRSCVSE 3476
Query: 8614 VACAEGTFPCSNGH-CINQTKVCDGHNDCHDEQVSDESL-ATCPGLPIDCRGVKVRCPN- 8784
C F C+ + CI CDG +DC D + L CP P C + CP
Sbjct: 3477 --CKPNDFVCTKTYKCIASWWRCDGQDDCGDGEDEGYFLKGVCPQFP--CDPGQFLCPKS 3532
Query: 8785 ----TNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRC-PSGRCIPETWQCDGD 8949
T C+ + LCDG DC + DE + FC + +C + +C +CIP T CD +
Sbjct: 3533 PRNTTAQCLYASKLCDGVKDCLEGEDEEKTFCEHFECTESQFKCGDKKKCIPLTSVCDKE 3592
Query: 8950 NDCSDGWDETHTNCTDTAGKKICVGDYLFQCDN------LKCISRAFIXXXXXXXXXXXX 9111
DC DG DE K C D+ F C N KCI + F
Sbjct: 3593 KDCDDGSDERSCEI------KSCKPDF-FACVNETTSQISKCIPKEFYCDGEDDCPNGQD 3645
Query: 9112 XHSR-HGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTE 9288
G G CT ++F C S +CIP+ CDG + C G DE K
Sbjct: 3646 EPDTCFGIGE--CTHEQFQCASG--------KCIPKRRKCDGTIDCRDGSDE-----KGC 3690
Query: 9289 KKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHAN-CTYSSC--QPDFFQCANHKCV 9459
KKEC C N+ C+ CDG C G+DE C +P C
Sbjct: 3691 KKEC---AIVCDNE-CVPVEELCDGKRKCTHGTDEEEEACAIKKLMEKPVLRTCGG---- 3742
Query: 9460 PNSWKCDGNDDCEDGSDEKDCP-----------------------KNSASAQKASKCSNG 9570
+KCDG DCEDG+DEK CP K+ + Q SN
Sbjct: 3743 ---FKCDGIIDCEDGADEKGCPDLECHLSNNASLICDGKVDCESGKDEQNCQNYGGYSNP 3799
Query: 9571 QFQCTSGECIDDAKVCDRNFDCTDRSDE-SSLCFIDECSLAEKPLCEQK--CMDMKI--- 9732
FQC S + + + +VCD +DC D DE +C + C+ K C+D+
Sbjct: 3800 LFQC-SRQTVKEWQVCDGRWDCADGLDEYPEMCKSRQARCFRIGFCDDKKQCLDVSTALC 3858
Query: 9733 -GYKCDCFEGFAID-------------------ISDQKSCHNVNECYEG----------- 9819
G+K DC +G + + C ++C +G
Sbjct: 3859 DGFK-DCSDGSDESPAHCKDMCKGMFRCTNGRCLDESARCDGRDDCGDGSDEDTCGLQCH 3917
Query: 9820 -ISGCSQKCDDKIGSY-KCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDG 9993
C QKC S +C C GY S+ + C+ E F L+N + + +
Sbjct: 3918 HFGTCPQKCWMAYNSTARCHCDVGYTKSTKYNDCEPLTKFTEIF--LSNGKRLHLMVAEE 3975
Query: 9994 NKYELAAQGFDNVVSLDIDL-----TEKKAYLIDQGKLRL-LRVDLDEMDSPLSSYETVL 10155
+ N++S ID Y + GK R+ +R P +
Sbjct: 3976 TRLRTVFNERMNIISGGIDFGYDMYKTTLMYSVGIGKNRVDIRTKKWSESKPSDEWG--- 4032
Query: 10156 RHNVYGTEG-IAVDWVGRKLYM----------LNRQERSIRVCELDGRFCKTLIRDRIQQ 10302
N T G IA D++ +Y+ L + +I V + +TLI +
Sbjct: 4033 EKNDESTAGLIAHDFMHNNVYLTESGSYIPGILFHTQENIYVAKSKDTNTRTLIVNSTGS 4092
Query: 10303 PKAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQ------DPIFKLAEHDLGWPNAIA 10464
++ V P + +F+T + P I LDG+P Q P L E ++ P ++
Sbjct: 4093 ITSLSVDPIQRLIFWTTGAPVPRILSAHLDGTPIAQLFKTGSQPHKALIERNIFDPKSLI 4152
Query: 10465 IDYFSDRLFWGDAHLNEIGFMDFDGNGRRHI-PAQRTSHVSSMVVFDDYLYWADWNLREV 10641
+D + RL+W D + + +DG RR + + SM + Y+Y +
Sbjct: 4153 LDSPNKRLYWIDGFKRTVETVSYDGRDRRTVRKFELGDSPVSMDIIGGYIYLVTLQ-GNI 4211
Query: 10642 LRCDKWTGKNETILKKTVQLPNDLR--IVHPMRQPA-----YPNPCGDNNGGCSHLCLIG 10800
+ K++GK ++ + +R I HP + NPC + +C+
Sbjct: 4212 HKMHKFSGKTNKYPQRIRDVAPRIRLLIAHPSKHTVSHITHQKNPCQSDYCPSETVCIPK 4271
Query: 10801 AGGNGY---TCSCPDQFVLLSDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDG 10971
NG C C K C P Q A D C C + C
Sbjct: 4272 EDTNGVLIPKCLCGAGRFFEESTKKCLPVHDMNQEASQCGDYFCYNNA-ACSAQKKC--- 4327
Query: 10972 SDEPGESICGQRICPVGEF--QCTNHNCT 11052
ICP G + QC + C+
Sbjct: 4328 ------------ICPPGFYGRQCEINECS 4344
Score = 148 bits (374), Expect = 3e-33
Identities = 105/295 (35%), Positives = 137/295 (45%), Gaps = 19/295 (6%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDE-----KDCPASTVDCSSQNVFMC 438
CK + + C T T+ CIA + RCD DC DG DE CP D F+C
Sbjct: 3477 CKPNDFVC-TKTY---KCIASWWRCDGQDDCGDGEDEGYFLKGVCPQFPCD---PGQFLC 3529
Query: 439 ADG-----RQCFDVSKKCDGKYDCRDLSD-EKDSCSRNHTACFQYQFRCADKTQCIQKSW 600
QC SK CDG DC + D EK C H C + QF+C DK +CI +
Sbjct: 3530 PKSPRNTTAQCLYASKLCDGVKDCLEGEDEEKTFC--EHFECTESQFKCGDKKKCIPLTS 3587
Query: 601 VCDGSKDCADGSDEPDTCEFKKCTANEFQCKNK------RCQPRKFRCDYYDDCGDNSDE 762
VCD KDC DGSDE +CE K C + F C N+ +C P++F CD DDC + DE
Sbjct: 3588 VCDKEKDCDDGSDE-RSCEIKSCKPDFFACVNETTSQISKCIPKEFYCDGEDDCPNGQDE 3646
Query: 763 -DEC-GEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCH 936
D C G C ++ C +G CI + + CDG+ DC DG+DE+ C + ++ C C
Sbjct: 3647 PDTCFGIGECTHEQFQC-ASGKCIPKRRKCDGTIDCRDGSDEKGCKKEC--AIVCDNECV 3703
Query: 937 PSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDC 1101
P E C K H T + CA ++ GF C + DC
Sbjct: 3704 PV----EELCDGKRKCT---HGTDEEEEACAIKKLMEKPVLRTCGGFKCDGIIDC 3751
Score = 147 bits (371), Expect = 7e-33
Identities = 185/773 (23%), Positives = 279/773 (35%), Gaps = 113/773 (14%)
Frame = +1
Query: 157 CNENDFRCND-GKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVS-CI 330
C E+ F+C D KCI CK D + C T +S CI
Sbjct: 3569 CTESQFKCGDKKKCIPLTSVCDKEKDCDDGSDERSCEIKSCKPDFFACVNETTSQISKCI 3628
Query: 331 AEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSD 510
+ CD DC +G DE D +C+ + F CA G+ C +KCDG DCRD SD
Sbjct: 3629 PKEFYCDGEDDCPNGQDEPDTCFGIGECTHEQ-FQCASGK-CIPKRRKCDGTIDCRDGSD 3686
Query: 511 EKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQC 690
EK C +C+ +CDG + C G+DE E + C +
Sbjct: 3687 EKGCKKECAIVC---------DNECVPVEELCDGKRKCTHGTDE----EEEACAIKKLME 3733
Query: 691 KNKRCQPRKFRCDYYDDCGDNSDEDEC----------------GEYRCPPGK--WNCPGT 816
K F+CD DC D +DE C G+ C GK NC
Sbjct: 3734 KPVLRTCGGFKCDGIIDCEDGADEKGCPDLECHLSNNASLICDGKVDCESGKDEQNCQNY 3793
Query: 817 G-----------HCIDQLKLCDGSKDCADGADE---------------------QQC--- 891
G + + ++CDG DCADG DE +QC
Sbjct: 3794 GGYSNPLFQCSRQTVKEWQVCDGRWDCADGLDEYPEMCKSRQARCFRIGFCDDKKQCLDV 3853
Query: 892 SQNLCPSL-GCQAGCHPSPH------GGECTCPSGYKLDDRF----HRTCSDIN------ 1020
S LC C G SP G C +G LD+ C D +
Sbjct: 3854 STALCDGFKDCSDGSDESPAHCKDMCKGMFRCTNGRCLDESARCDGRDDCGDGSDEDTCG 3913
Query: 1021 -ECAEFGYCDQLC-ANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLF 1194
+C FG C Q C + C C D + + LT +N ++ L
Sbjct: 3914 LQCHHFGTCPQKCWMAYNSTARCHC--DVGYTKSTKYNDCEPLTKFTEIFLSNGKRLHLM 3971
Query: 1195 VARREGLYRLNPKNPDEEVKKLASGEFIYGID-------FDYGDRKIFWTDRLAHSAFSA 1353
VA L + E + SG +G D + G K R + S
Sbjct: 3972 VAEETRL-----RTVFNERMNIISGGIDFGYDMYKTTLMYSVGIGKNRVDIRTKKWSESK 4026
Query: 1354 DVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGS----------RRIDVSSYD 1503
D+ GE + L +A D++ N +Y+ ESGS I V+
Sbjct: 4027 PSDEWGEKNDESTAGL--------IAHDFMHNNVYLTESGSYIPGILFHTQENIYVAKSK 4078
Query: 1504 GERRTVLLADGLTLPLDIALDPLRGEMFFTNQL---KLEAAAMDGT-----------NRR 1641
L+ + +++DP++ +F+T ++ +A +DGT +
Sbjct: 4079 DTNTRTLIVNSTGSITSLSVDPIQRLIFWTTGAPVPRILSAHLDGTPIAQLFKTGSQPHK 4138
Query: 1642 TLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLAL 1821
L+ + +++D KR+YW+D +E++ Y G DRR V + + P + +
Sbjct: 4139 ALIERNIFDPKSLILDSPNKRLYWIDGFKRTVETVSYDGRDRRTVRK-FELGDSPVSMDI 4197
Query: 1822 FDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHP-----MAQPGPGQS 1986
Y+Y + + ++ KF T N +P I P +A P
Sbjct: 4198 IGGYIYLVT-LQGNIHKMHKFSGKT---------NKYPQRIRDVAPRIRLLIAHPSKHTV 4247
Query: 1987 ECLAMKIENPCTNADC--EGMCILSKDNGGFGVGYKCACPIGQKLVNG-KRCI 2136
+ + +NPC + C E +CI +D G + KC C G+ K+C+
Sbjct: 4248 SHITHQ-KNPCQSDYCPSETVCIPKEDTNGVLIP-KCLCGAGRFFEESTKKCL 4298
Score = 134 bits (336), Expect = 8e-29
Identities = 78/234 (33%), Positives = 113/234 (47%), Gaps = 14/234 (5%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVSCIAEYQRCDNIT-DCADGSDEKDCPASTVD--------CSSQN 426
C + C+ + + + SC C+ + CADG D D C
Sbjct: 871 CSTSSSNCEHFCF-ATSCKGSVG-CEPVKCGCADGMKLVDNGKCVKDEHWEDPNGCDEDR 928
Query: 427 VFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVC 606
F C + R+C + CDG DC D SDE + C +F+C D T CI ++C
Sbjct: 929 EFTCLNSRKCIPKANLCDGDDDCGDGSDEDSNGICKDFKCVGNKFQC-DSTTCIPLEFLC 987
Query: 607 DGSKDCADGSDEPDT-CEF---KKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECG 774
DG DC DG+DE +T C+ +C+ +F+C N +C + RC+ DC + SDE++C
Sbjct: 988 DGKSDCNDGTDELETMCKTVPDVRCSVGQFRCSNTKCIDKSKRCNGIQDCENGSDEEDCP 1047
Query: 775 EYR-CPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLGCQAGC 933
+ C P ++ C GTG CI Q ++CDG C DG DE+ C +N G Q C
Sbjct: 1048 RSKLCTPTEFRC-GTGLCIKQSQVCDGKMQCLDGLDEKHCEENNSCIKGRQFRC 1100
Score = 132 bits (331), Expect = 3e-28
Identities = 84/263 (31%), Positives = 116/263 (43%), Gaps = 18/263 (6%)
Frame = +1
Query: 157 CNENDFRC-NDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIA 333
C EN+F+C + KCI E C S + + + CI+
Sbjct: 2640 CAENEFKCLHSDKCIPYE---DTCDQYNDCPMFDDEDAKYCSSRVCRPGYFDCGNGLCIS 2696
Query: 334 EYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDE 513
E + C+ DC + DE +C S ++ F C G C +C+ DC D SDE
Sbjct: 2697 ESKVCNRFNDCINFHDENNCTCS------KSEFKCDSGN-CIPGEDRCNHVQDCNDASDE 2749
Query: 514 KDSCSRNHTACFQYQF----RCADKTQCIQKSWVCDGSKDCADGSDEPDTC---EFKK-- 666
RN ++ ++ CA +QCI SW CDG+ DC DGSDE D +F K
Sbjct: 2750 IGCPYRNCSSLVEFGMSDLINCASTSQCIHPSWKCDGTNDCYDGSDELDCLVEFDFNKGS 2809
Query: 667 ------C-TANEFQC-KNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGH 822
C +A +F C + C P ++RCD DC D SDE C + C ++ C T
Sbjct: 2810 VSPPRSCDSATQFPCLATRNCMPNRWRCDGQPDCADGSDEANCEQKACNSFEFTCESTKK 2869
Query: 823 CIDQLKLCDGSKDCADGADEQQC 891
CI + CDG DC +G DE C
Sbjct: 2870 CIPLEQKCDGRSDCPNGEDENSC 2892
Score = 111 bits (277), Expect = 6e-22
Identities = 73/235 (31%), Positives = 108/235 (45%), Gaps = 13/235 (5%)
Frame = +1
Query: 436 CADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGS 615
CADG + D +GK + ++ + C + +F C + +CI K+ +CDG
Sbjct: 900 CADGMKLVD-----NGKCVKDEHWEDPNGCDEDR------EFTCLNSRKCIPKANLCDGD 948
Query: 616 KDCADGSDEPDT--CEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDE-----CG 774
DC DGSDE C+ KC N+FQC + C P +F CD DC D +DE E
Sbjct: 949 DDCGDGSDEDSNGICKDFKCVGNKFQCDSTTCIPLEFLCDGKSDCNDGTDELETMCKTVP 1008
Query: 775 EYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQN-LCPSLGCQAGCHPSPHG 951
+ RC G++ C T CID+ K C+G +DC +G+DE+ C ++ LC + G
Sbjct: 1009 DVRCSVGQFRCSNT-KCIDKSKRCNGIQDCENGSDEEDCPRSKLCTPTEFRCGTGLCIKQ 1067
Query: 952 GECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPG-----FTCSCLGDC 1101
+ LD + C + N C + CAN + F C + DC
Sbjct: 1068 SQVCDGKMQCLDGLDEKHCEENNSCIKGR--QFRCANKQSTCLDMIFQCDGVPDC 1120
Score = 110 bits (274), Expect = 1e-21
Identities = 140/597 (23%), Positives = 230/597 (38%), Gaps = 47/597 (7%)
Frame = +1
Query: 9223 LCDGDVTCAGGEDESTELCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHAN 9402
+C D + + +T C +EC+ G S C W CDG DC D SDE
Sbjct: 17 VCLSDSPDSSLKKANTSSCVPPMRECDSGT--PSGPKCYPEQWFCDGYPDCRDNSDEPPT 74
Query: 9403 CTYSSCQPDFFQCANHKCVPNSWKCDGNDDC---EDGSDEKDCPKNSASAQKASKCSNGQ 9573
C +C + F C KC+P + CDG DC DG ++ Q + C + +
Sbjct: 75 CK-RACLENEFVCKTGKCLPRGYLCDGQLDCGRFPDGLQDRSDESRELCNQPLN-CEHNE 132
Query: 9574 FQC-TSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDC 9750
+ C S +C+ K CD DC+D SDE +C + S A CE G KC C
Sbjct: 133 YACAASAQCVPLFKFCDGKLDCSDGSDE--VCRVKNISTAND--CEYGAAITIDGIKCYC 188
Query: 9751 FEGFAIDISDQKSCHNVNECYEGISG----CSQKC-DDKIGSYKCGCVDGYQLSSDDHSC 9915
+ ++++ C VN+C +G CSQ C D+K G++ C C D ++ C
Sbjct: 189 PKNKF--LNEKGKCEFVNQCDRLKNGLPPACSQGCTDNKNGTFSCFCFDPRLTVANGTHC 246
Query: 9916 KRTEMEPEPFFLLANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLI------ 10077
+ P + K I Y + N SL L + A +
Sbjct: 247 VAEKDVSIPSVAILTKQKI---------YTIQNGTMSNYSSLPRPLGKPGALTLVFQHPD 297
Query: 10078 -DQGKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGI----AVDWVGRKLYMLNRQERS- 10239
+ K+ +L + ++P S+ + NV G+E + AVD+ ++M+
Sbjct: 298 FPEAKVPILCLS----EAPTSNQSYITCGNVEGSEPVTKSYAVDFDISAIHMIRFDNFGN 353
Query: 10240 ----------IRVCELDG---RFCKTLIRDRIQQPKAIVVHPGKGYLFFTEWS-LQPYIG 10377
I +C+ D C T + + + G F T+ Q I
Sbjct: 354 NWIFTDASYYIFICKHDSVKISKCHTFAAGAMGTLQDVQYDGVNGQFFVTDSDYFQQGIW 413
Query: 10378 RIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHI 10557
RI + +L + P A+AID F+ L++ D+ N I +D++ N R +
Sbjct: 414 RIDVASGER-----NRLTTQPITSP-ALAIDPFTKTLYYVDSSANSIKAIDYNSNFSRIV 467
Query: 10558 PAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQL-------PND-- 10710
+ R + + + + + +A V + +E +LK ++ PN
Sbjct: 468 VSGRIAKEVTQLDYAEGKLFATLRDNRVFVANALESDSEAVLKTWQEITPPSNGGPNKVI 527
Query: 10711 LRIVHPMRQPAYPNPCGDN---NGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTCE 10872
+ + H R G N C +C IG ++C C D L+ + C+
Sbjct: 528 MEVFHFRRNANAWKNKGRNICKAASCDDIC-IGHIEKTFSCLCRDG--LIQKENKCQ 581
Score = 106 bits (264), Expect = 2e-20
Identities = 93/333 (27%), Positives = 136/333 (39%), Gaps = 37/333 (11%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQ 453
C ++++C HS CI CD DC DE S+ C F C +G
Sbjct: 2640 CAENEFKC----LHSDKCIPYEDTCDQYNDCPMFDDEDAKYCSSRVCRP-GYFDCGNGL- 2693
Query: 454 CFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADG 633
C SK C+ DC + DE N+ C + +F+C D CI C+ +DC D
Sbjct: 2694 CISESKVCNRFNDCINFHDE------NNCTCSKSEFKC-DSGNCIPGEDRCNHVQDCNDA 2746
Query: 634 SDEPDTCEFKKCTA-------NEFQCKN-KRCQPRKFRCDYYDDCGDNSDEDEC------ 771
SDE C ++ C++ + C + +C ++CD +DC D SDE +C
Sbjct: 2747 SDEIG-CPYRNCSSLVEFGMSDLINCASTSQCIHPSWKCDGTNDCYDGSDELDCLVEFDF 2805
Query: 772 --GEYRCPPG-----KWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPS--LGCQ 924
G P ++ C T +C+ CDG DCADG+DE C Q C S C+
Sbjct: 2806 NKGSVSPPRSCDSATQFPCLATRNCMPNRWRCDGQPDCADGSDEANCEQKACNSFEFTCE 2865
Query: 925 A--GCHPSPH--GGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHR---PGFTC 1083
+ C P G CP+G + ++ C N + F C NHR + C
Sbjct: 2866 STKKCIPLEQKCDGRSDCPNG-EDENSCDTECDSKNGNSTF-----RCTNHRCIPMAWRC 2919
Query: 1084 SCLGDCF-------TLQMEHGPGKDNLTMRGYC 1161
DC + +M+ PGK + + C
Sbjct: 2920 DGTDDCLDNAKSLGSDEMDCAPGKTSFHVPSRC 2952
Score = 83.2 bits (204), Expect = 2e-13
Identities = 173/784 (22%), Positives = 271/784 (34%), Gaps = 75/784 (9%)
Frame = +1
Query: 7669 DTAGEHLSTIASGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAG------- 7827
DT L ++G T +L++DP L+FW+ G PRI ++L G
Sbjct: 4079 DTNTRTLIVNSTGSIT-SLSVDPIQRLIFWTT-------GAPVPRILSAHLDGTPIAQLF 4130
Query: 7828 --GSR--KVIVSESISLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIAS---GY 7986
GS+ K ++ +I P ++ +D N+++YW D + +E YDG++R+ + G
Sbjct: 4131 KTGSQPHKALIERNIFDPKSLILDSPNKRLYWIDGFKRTVETVSYDGRDRRTVRKFELGD 4190
Query: 7987 RAKSLDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQ 8166
S+DI ++Y+ L + ++ K SG + R + +R+ + T +
Sbjct: 4191 SPVSMDIIGGYIYLV-TLQGNIHKMHKFSGKTNKYPQRIRDVAPRIRLLIAHPSKHTVSH 4249
Query: 8167 VCNALTSQLCKTDNGGCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLR 8346
+ + C++D + +C D G+ K C +E
Sbjct: 4250 ITH--QKNPCQSDYCPSETVCIPKEDTNGVLIPKCLCGAGRFFE---------------- 4291
Query: 8347 GSNSEPAKECLPPYNF-----QCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPE- 8508
E K+CLP ++ QCGD C A C ++ C C C E
Sbjct: 4292 ----ESTKKCLPVHDMNQEASQCGDYFC-YNNAACSAQKKCICPPGFYGRQCEINECSER 4346
Query: 8509 --DYNLCTNR-----RCIDSAKKCNHID-DCGDGSDELDCPSAVACAEGTFPC------- 8643
+ C R R I+ N+ DC E C +C T PC
Sbjct: 4347 CWNGETCAIRESGATRNIECHCPANYTQIDCATNVCEGVCGPRGSCK--TVPCTREEPHC 4404
Query: 8644 ------------SNGHCINQ--TKVCDGH----NDCHDEQVSDESLATCPGLPIDCRGVK 8769
S HC ++ K+C GH +C +Q S+ PG
Sbjct: 4405 RSYSYCECDKGWSGPHCRHKIDAKICYGHCFSGGECQGDQPSNLKCQCRPGF-------- 4456
Query: 8770 VRCPNTNICIQPADLCDGYDDCGDKADENQLFCM---NQQCAQHYVRCPSGRCIPETWQC 8940
N N C +C D+ N FC + + H + CPSG
Sbjct: 4457 ----NGNRC----------QNCKDRECLNGGFCSYFGSNRTMSHCI-CPSG--------Y 4493
Query: 8941 DGDNDCSDGWDETHTNCTDTA--GKKICVGDYLFQCDNLKCISRAFIXXXXXXXXXXXXX 9114
GDN C + C D G+K CV D+ + C
Sbjct: 4494 TGDN-CEE------YLCKDACSYGEK-CVYDFTNHLQPISCFCE-------------KNA 4532
Query: 9115 HSRHGCGNRTCTDQEFHCTSNAK-LAQP----KYECIPR--AWLCDGDVTCAGGEDESTE 9273
+ + + C Q C + K L P K +C+PR CD V C +
Sbjct: 4533 AAPNADCSPICHKQPNWCHNGGKCLDMPGSPGKCKCLPRFTGPRCDVPVLC-------DD 4585
Query: 9274 LCKTEKK--ECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCAN 9447
C K E N F C + C+ + C S CQ
Sbjct: 4586 YCTNNSKCIETNGTHFECECKPGFKGL-RCEQETLC------------SECQ------NG 4626
Query: 9448 HKCVPNSWK---CDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTSGECIDDAKVC 9618
KC+ + C C +G K C + +A + KC NG G C++
Sbjct: 4627 AKCIKQPSRTVLC----QCPEGLGGKYCEEITAVSCNQLKCQNG------GYCLEPDSDV 4676
Query: 9619 DRNF-DCTDRSD-ESSLCFIDECSLAEKPLC--EQKC-MDMKIGYKCDCFEGFAIDISDQ 9783
DRN C R + LC C C + KC ++ + +C+C++ F D
Sbjct: 4677 DRNRPQCVCRPGFQGILCGSHSCD----NFCHHDGKCSLNEEFEPQCECYKAFTGDRCQY 4732
Query: 9784 KSCH 9795
+ H
Sbjct: 4733 RVSH 4736
Score = 81.6 bits (200), Expect = 5e-13
Identities = 53/178 (29%), Positives = 72/178 (39%), Gaps = 21/178 (11%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQ 453
C +CD+ T C E CD DC D SDE P + +N F+C G+
Sbjct: 35 CVPPMRECDSGTPSGPKCYPEQWFCDGYPDCRDNSDE---PPTCKRACLENEFVCKTGK- 90
Query: 454 CFDVSKKCDGKYDC-------RDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDG 612
C CDG+ DC +D SDE C ++ CA QC+ CDG
Sbjct: 91 CLPRGYLCDGQLDCGRFPDGLQDRSDESRELCNQPLNCEHNEYACAASAQCVPLFKFCDG 150
Query: 613 SKDCADGSDEPDTCEFKK-CTANEFQ-------------CKNKRCQPRKFRCDYYDDC 744
DC+DGSDE C K TAN+ + C + K +C++ + C
Sbjct: 151 KLDCSDGSDE--VCRVKNISTANDCEYGAAITIDGIKCYCPKNKFLNEKGKCEFVNQC 206
Score = 79.3 bits (194), Expect = 2e-12
Identities = 74/265 (27%), Positives = 98/265 (36%), Gaps = 5/265 (1%)
Frame = +1
Query: 11629 PCSESEFRCNDGKCIPGSKVCDGTIQCSDGL-DESQCTLRRCLPGHRQCDDG-TCIAEHK 11802
PCS+ RC D CIP S T C+ G + + + C P C CIA
Sbjct: 3438 PCSQPA-RC-DNLCIPASSPEAFTCMCAQGFRSDGRSCVSECKPNDFVCTKTYKCIASWW 3495
Query: 11803 WCDRKKDCPNAADELHCED--VSRRTCSPFEFECANSVCIPRKFMXXXXXXXXXXSDETS 11976
CD + DC + DE + + C P +F C S PR T+
Sbjct: 3496 RCDGQDDCGDGEDEGYFLKGVCPQFPCDPGQFLCPKS---PRN---------------TT 3537
Query: 11977 SECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSFSEYGDCSSD 12156
++C A +LC+G DC + DE + C F +C+
Sbjct: 3538 AQCLYAS-------------------KLCDGVKDCLEGE--DEEKTFCEHF----ECTES 3572
Query: 12157 QFKCANGK-CVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKHICTDVRDG 12333
QFKC + K C+ T CD++ DC D SDE C K A N I +
Sbjct: 3573 QFKCGDKKKCIPLTSVCDKEKDCDDGSDERSCEIKSCKPDFFACVNET-TSQISKCIPKE 3631
Query: 12334 FYCHCRDGFRPDPQSPKECIDIDEC 12408
FYC D P C I EC
Sbjct: 3632 FYCDGEDDCPNGQDEPDTCFGIGEC 3656
Score = 70.9 bits (172), Expect = 9e-10
Identities = 73/291 (25%), Positives = 112/291 (38%), Gaps = 12/291 (4%)
Frame = +1
Query: 11710 SDGLDES--QCTLRRCLPGHRQCDDGT-----CIAEHKWCDRKKDCPNAADELHCEDVSR 11868
SD D S + C+P R+CD GT C E +CD DC + +DE +
Sbjct: 20 SDSPDSSLKKANTSSCVPPMRECDSGTPSGPKCYPEQWFCDGYPDCRDNSDE---PPTCK 76
Query: 11869 RTCSPFEFECANSVCIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLN 12048
R C EF C C+PR ++ CD L
Sbjct: 77 RACLENEFVCKTGKCLPRGYL----------------------CDGQLD----------- 103
Query: 12049 ILQLCNGFNDCGPNDFSDEHLSMCSSFSEYGDCSSDQFKCA-NGKCVNGTVACDRKDDCG 12225
C F D G D SDE +C+ + +C +++ CA + +CV CD K DC
Sbjct: 104 ----CGRFPD-GLQDRSDESRELCN---QPLNCEHNEYACAASAQCVPLFKFCDGKLDCS 155
Query: 12226 DASDEIGCSKHGGKTSCEAFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDE 12405
D SDE+ K+ C++ DG C+C + + E ++ +
Sbjct: 156 DGSDEVCRVKN--------ISTANDCEYGAAITIDGIKCYCPKNKFLNEKGKCEFVNQCD 207
Query: 12406 CAGNN---TCTQLCLNTK-GSYLCRCHEDYENNVVVGSMTGKDCRAKGDAA 12546
N C+Q C + K G++ C C ++ + V + G C A+ D +
Sbjct: 208 RLKNGLPPACSQGCTDNKNGTFSCFC---FDPRLTVAN--GTHCVAEKDVS 253
Score = 69.3 bits (168), Expect = 3e-09
Identities = 83/382 (21%), Positives = 146/382 (37%), Gaps = 31/382 (8%)
Frame = +1
Query: 6241 GHPCHINNGNCDHICIPLMFAQRTCTCANGYVKDGQ-TSCKLFDESFVIVATKTKVIGYP 6417
G CH + G C C + C C GY K + C+ + I + K +
Sbjct: 3913 GLQCH-HFGTCPQKCWMAYNSTARCHCDVGYTKSTKYNDCEPLTKFTEIFLSNGKRLHLM 3971
Query: 6418 I-DETQSKGVAMEPIGGLSITGVDYDYESKTIYVAEASGINKG---ITAYTIGESSPRAV 6585
+ +ET+ + V E + +S G+D+ Y+ + + GI K I ES P
Sbjct: 3972 VAEETRLRTVFNERMNIIS-GGIDFGYDMYKTTLMYSVGIGKNRVDIRTKKWSESKPSDE 4030
Query: 6586 IRDSIGSLTIKSLAIDWINYNMYFINHDA--------ERTNIEVSKLDGTYRKILLTTKT 6741
+ T +A D+++ N+Y + + NI V+K T + L+ T
Sbjct: 4031 WGEKNDESTAGLIAHDFMHNNVYLTESGSYIPGILFHTQENIYVAKSKDTNTRTLIVNST 4090
Query: 6742 ETPSSIAVDPVSRYLYWADQGQKPTIQRSFLDGS-----------RREVIVSSGIAEPTD 6888
+ +S++VDP+ R ++W P I + LDG+ + ++ I +P
Sbjct: 4091 GSITSLSVDPIQRLIFWTTGAPVPRILSAHLDGTPIAQLFKTGSQPHKALIERNIFDPKS 4150
Query: 6889 LVVDVASKMIYWSDAKMDGIYRVRSTGGTPELVRSDIASAAGVALH--GQNMYWT--DNR 7056
L++D +K +YW D + V G VR + V++ G +Y
Sbjct: 4151 LILDSPNKRLYWIDGFKRTVETVSYDGRDRRTVRKFELGDSPVSMDIIGGYIYLVTLQGN 4210
Query: 7057 LEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRASSPCQITDNLRKSPCT 7236
+ K+ + + K N+ + L I + + ++ +PCQ P
Sbjct: 4211 IHKMHKFSGKTNKYPQRIRDVAPRIRLL-IAHPSKHTVSHITHQKNPCQSD----YCPSE 4265
Query: 7237 QLCFA---TPGTQTPTCSCARG 7293
+C T G P C C G
Sbjct: 4266 TVCIPKEDTNGVLIPKCLCGAG 4287
Score = 65.9 bits (159), Expect = 3e-08
Identities = 64/282 (22%), Positives = 111/282 (38%), Gaps = 14/282 (4%)
Frame = +1
Query: 2503 DELVRRQLITELRDPVSVVVHPWKGLLFYAEAMRPAAIYRCHIDG-----------QNCQ 2649
D R ++ S+ V P + L+F+ I H+DG Q +
Sbjct: 4079 DTNTRTLIVNSTGSITSLSVDPIQRLIFWTTGAPVPRILSAHLDGTPIAQLFKTGSQPHK 4138
Query: 2650 VIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKN---VVKLDIDNPIPVAITI 2820
+ + P + +D RL W D +T+ + +DG++ V K ++ + PV++ I
Sbjct: 4139 ALIERNIFDPKSLILDSPNKRLYWIDGFKRTVETVSYDGRDRRTVRKFELGDS-PVSMDI 4197
Query: 2821 MNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHP 3000
+ YIY V + +I ++HK +G +K + I L A ++ +++P
Sbjct: 4198 IGGYIYLVTLQG-NIHKMHKFSGKTNKYPQRIRDVAPRIRLLIAHPSKHTVSHITHQKNP 4256
Query: 3001 CRASQCTQLCFATPSESHPNELEAKCACRQGFMINKENNHSCQKDPAEKIEQLCSSNSTQ 3180
C++ C P E L KC C G +E+ C P + Q S
Sbjct: 4257 CQSDYCPSETVCIPKEDTNGVLIPKCLCGAGRFF-EESTKKCL--PVHDMNQEASQCGDY 4313
Query: 3181 FQCKNGRCIPKEWKCDGENDCLDESDEIDEKGDKCFHETECA 3306
F C N + KC EI+E ++C++ CA
Sbjct: 4314 F-CYNNAACSAQKKCICPPGFYGRQCEINECSERCWNGETCA 4354
Score = 51.6 bits (122), Expect = 6e-04
Identities = 60/273 (21%), Positives = 106/273 (37%), Gaps = 37/273 (13%)
Frame = +1
Query: 12967 KKIVAGHLQQPTALITAPSAGRICY--------SDAGLHAKIECADMDGTHRQIIVKDLV 13122
K IV G++ P A+ + + + +DA A IE + +DG+ R+ +V
Sbjct: 706 KIIVRGNMSNPRAIAVHVAKSYLFWGSWSEDRQNDATTPAMIERSKLDGSERKTLVSKNS 765
Query: 13123 FSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHD----RHIPYAVDVFENHI 13290
+ +D K + +YW D ++ + +G++R ++ H PY + F+NHI
Sbjct: 766 MWINGLTLDL-KNDFLYWCDAYRNVIERIRWNGADREVIIQGVDKISH-PYGLAFFDNHI 823
Query: 13291 YWLSRESKTLYVQDKFGRGRVSVLASDLED--------GHTVRVSQKYAKDTQRTVSGC- 13443
++ +F RG V + + D TV + ++ S C
Sbjct: 824 FF-----------TEFKRGAVKRVNVNFPDQVQEIFQYSATVFELAVFKNSLSKSTSPCS 872
Query: 13444 -ERAQCSHLCVSLPSTG------FACLCPDGIVPQLDGSCA-TQHVE---ALTMPKQCKC 13590
+ C H C + G C C DG+ +G C +H E ++ C
Sbjct: 873 TSSSNCEHFCFATSCKGSVGCEPVKCGCADGMKLVDNGKCVKDEHWEDPNGCDEDREFTC 932
Query: 13591 TNGGKC-----RLDGSCECTSDFEGDQCEKESS 13674
N KC DG +C GD +++S+
Sbjct: 933 LNSRKCIPKANLCDGDDDC-----GDGSDEDSN 960
Score = 41.6 bits (96), Expect = 0.57
Identities = 65/287 (22%), Positives = 93/287 (31%), Gaps = 54/287 (18%)
Frame = +1
Query: 391 CPASTVDCSSQNV-------FMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSR----NH 537
CP+ TV ++ +C GR + +KKC D++ E C N+
Sbjct: 4262 CPSETVCIPKEDTNGVLIPKCLCGAGRFFEESTKKC---LPVHDMNQEASQCGDYFCYNN 4318
Query: 538 TACFQ---------YQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTAN--EF 684
AC + R + +C ++ W + G+ C C AN +
Sbjct: 4319 AACSAQKKCICPPGFYGRQCEINECSERCWNGETCAIRESGATRNIECH---CPANYTQI 4375
Query: 685 QCKNKRCQPRKFRCDYYDDCGD---NSDEDECGEY---RCPPGKWNCPGTGHCIDQLKLC 846
C C+ C C +E C Y C G W+ P H ID K+C
Sbjct: 4376 DCATNVCEGV---CGPRGSCKTVPCTREEPHCRSYSYCECDKG-WSGPHCRHKIDA-KIC 4430
Query: 847 DGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECT--------------------- 963
G C G + C + +L CQ C P +G C
Sbjct: 4431 YGH--CFSGGE---CQGDQPSNLKCQ--CRPGFNGNRCQNCKDRECLNGGFCSYFGSNRT 4483
Query: 964 -----CPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSC 1089
CPSGY D+ C D C+ C NH +C C
Sbjct: 4484 MSHCICPSGYTGDNCEEYLCKD--ACSYGEKCVYDFTNHLQPISCFC 4528
Score = 39.7 bits (91), Expect = 2.2
Identities = 25/85 (29%), Positives = 33/85 (38%), Gaps = 8/85 (9%)
Frame = +1
Query: 13441 CERAQCSHLCVSLPSTGFACLCPDGIVPQLDGSCATQHVEALTMPKQCKCTNGGKC---- 13608
C Q C+ PS C CP+G+ G + + A++ Q KC NGG C
Sbjct: 4620 CSECQNGAKCIKQPSRTVLCQCPEGL-----GGKYCEEITAVSC-NQLKCQNGGYCLEPD 4673
Query: 13609 ----RLDGSCECTSDFEGDQCEKES 13671
R C C F+G C S
Sbjct: 4674 SDVDRNRPQCVCRPGFQGILCGSHS 4698
>gi|1389559|gb|AAB02882.1| glycoprotein 330
Length = 1751
Score = 1096 bits (2834), Expect = 0.0
Identities = 626/1796 (34%), Positives = 906/1796 (49%), Gaps = 39/1796 (2%)
Frame = +1
Query: 8392 FQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHID 8571
F C +G CI CD+ C D SDE + C +C C N RC+ + +C++ +
Sbjct: 1 FTCSNGRCISEEWKCDNDNGCGDGSDEMESVCALHTCSPTAFTCANGRCVQYSYRCDYYN 60
Query: 8572 DCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPGLPI 8751
DCGDGSDE C A F C+N CI + +C+G ++CHD SDE CP
Sbjct: 61 DCGDGSDETGCLFRDCNATTEFMCNNRRCIPREFICNGVDNCHDNNTSDEK--NCPDRT- 117
Query: 8752 DCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCIPET 8931
C+ +C N+NICI LCDG +DCGD +DEN +C C+ +C SGRCIP+T
Sbjct: 118 -CQSGYPKCHNSNICIPRVYLCDGDNDCGDNSDENPTYCTTHTCSSSEFQCASGRCIPQT 176
Query: 8932 WQ-CDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXXXX 9108
+ CD + DC D DE ++C + ++ C+ D F+CD +CI +I
Sbjct: 177 FGICDQETDCFDASDEP-SSCGHS--ERTCLSDE-FKCDGGRCIPNEWICDGDNDCGDMS 232
Query: 9109 XXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTE 9288
RH C N+ C+D EF C ++ P CIP++W DGDV C G DE +
Sbjct: 233 DEDKRHQCQNQNCSDSEFPCVNDRP---PDRRCIPQSWPPDGDVDCTDGHDE---IQNCT 286
Query: 9289 KKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCANHKCVPNS 9468
++ C++ EF C CI + CD NDC D SDE C Y +CQ + F C N +C+ +
Sbjct: 287 RRTCSENEFTCGYGLCIPKIFRCDRHNDCGDYSDERG-CLYQTCQQNQFTCQNGRCISKT 345
Query: 9469 WKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRS 9648
+ CD ++DC DGSDE C +F+C +G CI+ K+C+ DC D S
Sbjct: 346 FVCDEDNDCGDGSDEL----MHLCHTPEPTCPPHEFKCDNGRCIEMMKLCNHLDDCLDNS 401
Query: 9649 DESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNECYEGISG 9828
DE C I+EC C+ C D + C C G+ + +SD+++C +++EC E
Sbjct: 402 DEKG-CGINECHDPSISGCDHNCTDTLTSFYCSCRPGYKL-MSDKRTCVDIDECTEMPFV 459
Query: 9829 CSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYEL 10008
CSQKC++ IGSY C C GY D +C++ EP+ + +N++Y+R ++IDG Y L
Sbjct: 460 CSQKCENVIGSYICKCAPGYLREPDGKTCRQNS-NIEPYLIFSNRYYLRNLTIDGYFYSL 518
Query: 10009 AAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIA 10188
+G DNVV+LD D EK+ Y ID + + R+ L++ + ET++ H + E +A
Sbjct: 519 ILEGLDNVVALDFDRVEKRLYWIDTQRQVIERMFLNKTNK-----ETIINHRLPAAESLA 573
Query: 10189 VDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQ--------QPKAIVVHPGKGYLF 10344
VDWV RKLY L+ + + V +L+G + L + + P+ + +HP GYL+
Sbjct: 574 VDWVSRKLYWLDARLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLY 633
Query: 10345 FTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGF 10524
+ +W + YIGR+ +DG+ + + L WPN I IDY +D L+W DAHL I +
Sbjct: 634 WADWGHRAYIGRVGMDGTNKSV-----IISTKLEWPNGITIDYTNDLLYWADAHLGYIEY 688
Query: 10525 MDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLP 10704
D +G+ R + H ++ +F+D +YW DWN R V + +K+ G N L T P
Sbjct: 689 SDLEGHHRHTVYDGALPHPFAITIFEDTIYWTDWNTRTVEKGNKYDGSNRQTLVNTTHRP 748
Query: 10705 NDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQF--VLLSDQKTCEPN 10878
D+ + HP RQP NPCG NNGGCSHLCLI GG G+TC CPD F + LS C P
Sbjct: 749 FDIHVYHPYRQPIVSNPCGTNNGGCSHLCLIKPGGKGFTCECPDDFRTLQLSGSTYCMPM 808
Query: 10879 CTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRP 11058
C+ QF C ++ KCIP W CDG+ DC DGSDE ++C QR C +G+FQC++ NCT P
Sbjct: 809 CSSTQFLCANNE-KCIPIWWKCDGQKDCSDGSDE--LALCPQRFCRLGQFQCSDGNCTSP 865
Query: 11059 FQIXXXXXXXXXXXXEQN--CDK-ACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEAD 11229
+ E C+ CD ++C A RCIP + SDE
Sbjct: 866 QTLCNAHQNCPDGSDEDRLLCENHHCDSNEWQC-ANKRCIPESWQCDSFNDCEDNSDEDS 924
Query: 11230 TLCMSAERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXE-TPEC-AQIECKKGWTR-- 11397
+ C A R C +FRC N +CI +AW+ E EC + +T
Sbjct: 925 SHC--ASRTCRPGQFRCANGRCIPQAWKCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFS 982
Query: 11398 CSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMCDTEND 11577
C ++YRCIP WA CNG DDCRDNSDE TC VG+FRC + CIP RW CD +ND
Sbjct: 983 CKTNYRCIPKWAVCNGVDDCRDNSDEQGCEERTCHPVGDFRC-KNHHCIPLRWKCDGQND 1041
Query: 11578 CGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQC-SDGLDESQCTLRRCL 11754
CGDNSDE + + R C+ESEFRC + +CIP +CD D DE C +R C
Sbjct: 1042 CGDNSDEENCA----PRECTESEFRCVNQQCIPSRWICDHYNDLWGDNSDERDCEMRTCH 1097
Query: 11755 PGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCED--VSRRTCSPFEFECANSVCIPRKF 11928
P + QC G + CD DC +A+DE C C FEC N VCIP +
Sbjct: 1098 PEYFQCTSGHRVHSELKCDGSADCLDASDEADCPTRFPDGAYCQATMFECKNHVCIPPYW 1157
Query: 11929 MXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEH 12108
SDE C C+ P RFRC ++R C+ ++CNG +DCG D +DE
Sbjct: 1158 KCDGDDDCGDGSDEELHLCLDVPCNSPNRFRCDNNR-CIYSHEVCNGVDDCG--DGTDET 1214
Query: 12109 LSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFG 12288
C + C+ ++KC NG C+ CD DDCGD SDE+GC+K +T E
Sbjct: 1215 EEHCRKPTP-KPCTEYEYKCGNGHCIPHDNVCDDADDCGDWSDELGCNKGKERTCAENI- 1272
Query: 12289 NNGGCKHICTDVRD-GFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGSYLC 12465
C+ CT + + GF C C GF + C+DI+EC TC Q C NTKGSY C
Sbjct: 1273 ----CEQNCTQLNEGGFICSCTAGFETNVFDRTSCLDINECEQFGTCPQHCRNTKGSYEC 1328
Query: 12466 RCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGSGTNRHXXXXXXXXXX 12645
C + + + + GK C A+G + +++ + + + +L + +
Sbjct: 1329 VCADGFTS---MSDRPGKRCAAEGSSPLLLLPDNVRIRKYNLSSERFSEYLQDEEYIQAV 1385
Query: 12646 XXXXXXXXPRKELMYWI---DGSE-RTIYRSAIANGNQSHEGQKLDVDFAAMGVV-PTAI 12810
++Y+ +GS I R+ I N +VD V+ P I
Sbjct: 1386 DYDWDPEDIGLSVVYYTVRGEGSRFGAIKRAYIPNFESGRNNLVQEVDLKLKYVMQPDGI 1445
Query: 12811 AVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHL 12990
AVD+ +++ + V + KR I V DGRY K +++ L
Sbjct: 1446 AVDWVGRHIYWSDV-----------KNKR------------IEVAKLDGRYRKWLISTDL 1482
Query: 12991 QQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRI 13170
QP A+ P G + ++D G K+E A M+G I+V + + PT ++ID +RI
Sbjct: 1483 DQPAAIAVNPKLGLMFWTDWGKEPKLESAWMNGEDPNILVFEDLGWPTGLSIDYLNNDRI 1542
Query: 13171 YWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSRESKTLYVQDKFGRGR 13350
YW D K ++ + DG++R + + PY++D+FE+ +YW+S+E ++ Q+KFG+G+
Sbjct: 1543 YWSDFKEDVIETIKYDGTDRRVIAKEAMNPYSLDIFEDQLYWISKEKGEVWKQNKFGQGK 1602
Query: 13351 ------VSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTGFACLCPD 13512
V+ + + H +R + ++V + CSHLC+ P G++C CP
Sbjct: 1603 KEKTLVVNPWLTQVRIFHQLRYN--------KSVPNLCKQICSHLCLLRPG-GYSCACPQ 1653
Query: 13513 G--IVPQLDGSCATQHVEALTMPKQCKCTNGGKCRLDGS----CECTSDFEGDQCE 13662
G + C + +P C+C +GG C D + C+C S + G CE
Sbjct: 1654 GSSFIEGSTTECDAAIELPINLPPPCRCMHGGNCYFDETDLPKCKCPSGYTGKYCE 1709
Score = 508 bits (1308), Expect = e-141
Identities = 385/1310 (29%), Positives = 582/1310 (44%), Gaps = 98/1310 (7%)
Frame = +1
Query: 7198 CQITDNLRKSP--CTQLCFATPGTQTPTCSCARGVLK---GRTCEEP---DTYIMFSDGD 7353
C D + P C+Q C G+ C CA G L+ G+TC + + Y++FS+
Sbjct: 447 CVDIDECTEMPFVCSQKCENVIGSYI--CKCAPGYLREPDGKTCRQNSNIEPYLIFSNRY 504
Query: 7354 KIIDVAIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAE 7533
+ ++ I+ + + N+ D D +R+Y++ + + + N E
Sbjct: 505 YLRNLTIDGYFYSLI-----LEGLDNVVALDFDRVEKRLYWIDTQRQVIERMFLNKTNKE 559
Query: 7534 ---NPRLVFGASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTIAS 7704
N RL S + +DW+++K+Y+ R + D G H +A
Sbjct: 560 TIINHRLPAAES-------------LAVDWVSRKLYWLDARLDGLFVSDLNGGHRRMLAQ 606
Query: 7705 G----------DWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSE 7854
D LA+ P G L+W+D G++ G R + G ++ VI+S
Sbjct: 607 HCVDANNTFCFDNPRGLALHPQYGYLYWADWGHRAYIG-------RVGMDGTNKSVIIST 659
Query: 7855 SISLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGY--RAKSLDIWDRWLYM 8028
+ P I +D+ N +YWAD + IE +D +G +R + G ++ I++ +Y
Sbjct: 660 KLEWPNGITIDYTNDLLYWADAHLGYIEYSDLEGHHRHTVYDGALPHPFAITIFEDTIYW 719
Query: 8029 SDPLSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDN 8208
+D + V + +K GS + +V+ P D+ + + S C T+N
Sbjct: 720 TDWNTRTVEKGNKYDGSNRQTLVNTTHRP---------FDIHVYHPYRQPIVSNPCGTNN 770
Query: 8209 GGCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSE----PAKEC 8376
GGC LC + G C C D + +Q G Y C+ S+++ ++C
Sbjct: 771 GGCSHLCLIKPGGKGFT-----CECPDDFRTLQLSGSTY---CMPMCSSTQFLCANNEKC 822
Query: 8377 LPPY---------------------------NFQCGDGSCILLGATCDSKPDCADASDEN 8475
+P + FQC DG+C C++ +C D SDE+
Sbjct: 823 IPIWWKCDGQKDCSDGSDELALCPQRFCRLGQFQCSDGNCTSPQTLCNAHQNCPDGSDED 882
Query: 8476 PNYCNTRSCPEDYNLCTNRRCIDSAKKCNHIDDCGDGSDE--LDCPSAVACAEGTFPCSN 8649
C C + C N+RCI + +C+ +DC D SDE C S C G F C+N
Sbjct: 883 RLLCENHHCDSNEWQCANKRCIPESWQCDSFNDCEDNSDEDSSHCASR-TCRPGQFRCAN 941
Query: 8650 GHCINQTKVCDGHNDCHDEQVSDESLATCPGLPIDCRG-VKVRCPNTNICIQPADLCDGY 8826
G CI Q CD NDC D SDE + C C + C CI +C+G
Sbjct: 942 GRCIPQAWKCDVDNDCGDH--SDEPIEECMSSAHLCDNFTEFSCKTNYRCIPKWAVCNGV 999
Query: 8827 DDCGDKADENQLFCMNQQCAQHYV---RCPSGRCIPETWQCDGDNDCSDGWDETH---TN 8988
DDC D +DE C + C H V RC + CIP W+CDG NDC D DE +
Sbjct: 1000 DDCRDNSDEQG--CEERTC--HPVGDFRCKNHHCIPLRWKCDGQNDCGDNSDEENCAPRE 1055
Query: 8989 CTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHC 9168
CT++ F+C N +CI +I C RTC + F C
Sbjct: 1056 CTESE----------FRCVNQQCIPSRWICDHYNDLWGDNS--DERDCEMRTCHPEYFQC 1103
Query: 9169 TSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKE---CNKGEFRCSNQHCI 9339
TS + + CDG C DE+ C T + C F C N CI
Sbjct: 1104 TSGHR--------VHSELKCDGSADCLDASDEAD--CPTRFPDGAYCQATMFECKNHVCI 1153
Query: 9340 HSTWECDGDNDCLDGSDEHAN-CTYSSC-QPDFFQCANHKCVPNSWKCDGNDDCEDGSDE 9513
W+CDGD+DC DGSDE + C C P+ F+C N++C+ + C+G DDC DG+DE
Sbjct: 1154 PPYWKCDGDDDCGDGSDEELHLCLDVPCNSPNRFRCDNNRCIYSHEVCNGVDDCGDGTDE 1213
Query: 9514 KD--CPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSL 9687
+ C K + C+ +++C +G CI VCD DC D SDE E +
Sbjct: 1214 TEEHCRKPT-----PKPCTEYEYKCGNGHCIPHDNVCDDADDCGDWSDELGCNKGKERTC 1268
Query: 9688 AEKPLCEQKCMDM-KIGYKCDCFEGFAIDISDQKSCHNVNECYEGISGCSQKCDDKIGSY 9864
AE +CEQ C + + G+ C C GF ++ D+ SC ++NEC E C Q C + GSY
Sbjct: 1269 AEN-ICEQNCTQLNEGGFICSCTAGFETNVFDRTSCLDINEC-EQFGTCPQHCRNTKGSY 1326
Query: 9865 KCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYELAAQGFDNVVSLD 10044
+C C DG+ SD + P LL + IRK ++ ++ Q + + ++D
Sbjct: 1327 ECVCADGFTSMSDRPGKRCAAEGSSPLLLLPDNVRIRKYNLSSERFSEYLQDEEYIQAVD 1386
Query: 10045 IDLTE----------------------KKAYL--IDQGKLRLLRVDLDEMDSPLSSYETV 10152
D K+AY+ + G+ L++ E+D L
Sbjct: 1387 YDWDPEDIGLSVVYYTVRGEGSRFGAIKRAYIPNFESGRNNLVQ----EVDLKLK----- 1437
Query: 10153 LRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGK 10332
V +GIAVDWVGR +Y + + + I V +LDGR+ K LI + QP AI V+P
Sbjct: 1438 ---YVMQPDGIAVDWVGRHIYWSDVKNKRIEVAKLDGRYRKWLISTDLDQPAAIAVNPKL 1494
Query: 10333 GYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYF-SDRLFWGDAHL 10509
G +F+T+W +P + ++G +DP + E DLGWP ++IDY +DR++W D
Sbjct: 1495 GLMFWTDWGKEPKLESAWMNG----EDPNILVFE-DLGWPTGLSIDYLNNDRIYWSDFKE 1549
Query: 10510 NEIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKW-TGKNETILK 10686
+ I + +DG RR I A+ + S+ +F+D LYW EV + +K+ GK E L
Sbjct: 1550 DVIETIKYDGTDRRVI-AKEAMNPYSLDIFEDQLYWISKEKGEVWKQNKFGQGKKEKTLV 1608
Query: 10687 KTVQLPNDLRIVHPMR-QPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCP 10833
L +RI H +R + PN C CSHLCL+ G GY+C+CP
Sbjct: 1609 VNPWL-TQVRIFHQLRYNKSVPNLCKQI---CSHLCLLRPG--GYSCACP 1652
Score = 404 bits (1038), Expect = e-110
Identities = 246/738 (33%), Positives = 371/738 (49%), Gaps = 22/738 (2%)
Frame = +1
Query: 3172 STQFQCKNGRCIPKEWKCDGENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKKCIPA 3351
+T+F C N RCIP+E+ C+G ++C D + DEK C T C KC N+ CIP
Sbjct: 79 TTEFMCNNRRCIPREFICNGVDNCHDNNTS-DEKN--CPDRT-CQSGYPKCHNSNICIPR 134
Query: 3352 QXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXE 3531
YC C++ +FQC + RCIP+ + +
Sbjct: 135 VYLCDGDNDCGDNSDENPTYCTTH---TCSSSEFQCASGRCIPQTFGICDQETDCFDASD 191
Query: 3532 KLEMCGNA--TCAANQFSCANGRCIPIYWLCDGDNDCYDGTDEDKE-RCPPVQCSALQFR 3702
+ CG++ TC +++F C GRCIP W+CDGDNDC D +DEDK +C CS +F
Sbjct: 192 EPSSCGHSERTCLSDEFKCDGGRCIPNEWICDGDNDCGDMSDEDKRHQCQNQNCSDSEFP 251
Query: 3703 CANGR----QCVPLRNHXXXXXXXXXXXXXXXXAVTAESCTPDQFKCVSSGLCIPASWKX 3870
C N R +C+P ++ T +C+ ++F C GLCIP ++
Sbjct: 252 CVNDRPPDRRCIP-QSWPPDGDVDCTDGHDEIQNCTRRTCSENEFTC-GYGLCIPKIFRC 309
Query: 3871 XXXXXXXXXSDEPKFGCTSGRQCSSDQFKCGNGRCILNNWLCDGENDCGDGSDESSERGC 4050
SDE GC + C +QF C NGRCI ++CD +NDCGDGSDE C
Sbjct: 310 DRHNDCGDYSDER--GCLY-QTCQQNQFTCQNGRCISKTFVCDEDNDCGDGSDELMHL-C 365
Query: 4051 KTSMNARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCSF 4230
T CP C+N + CI + +LC+ C +DE G + +GC
Sbjct: 366 HTPEPT--CPPHEFKCDNGR--CIEMMKLCNHLDDCLDNSDEKGCGINECHDPSISGCDH 421
Query: 4231 KCHNSPNGPICSCPFGEQLVN-KTKCEPENECLDSSS-CSQRCKDEKHGFTCSCDEGYEL 4404
C ++ CSC G +L++ K C +EC + CSQ+C++ + C C GY
Sbjct: 422 NCTDTLTSFYCSCRPGYKLMSDKRTCVDIDECTEMPFVCSQKCENVIGSYICKCAPGYLR 481
Query: 4405 DVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGAIVE---NAIALAWDSLTDR 4575
+ D +TC+ N++ I+ NR Y + +D + + I+E N +AL +D + R
Sbjct: 482 EPDGKTCRQNSNIEPYLIF---SNRYYLRNLTIDGYF-YSLILEGLDNVVALDFDRVEKR 537
Query: 4576 IYWSDIREKKILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVDSSLNTIEVANLE 4755
+YW D + + I N TN I L E +A+DWV R LYW+D+ L+ + V++L
Sbjct: 538 LYWIDTQRQVIERMFLNKTNKETIINHRLPAAESLAVDWVSRKLYWLDARLDGLFVSDLN 597
Query: 4756 DPKQRTLLVH----QNV---SQPRGIAVDPRKGVMFWTDWGQNPCIERASMDGTDRQIIV 4914
+R L H N PRG+A+ P+ G ++W DWG I R MDGT++ +I+
Sbjct: 598 GGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLYWADWGHRAYIGRVGMDGTNKSVII 657
Query: 4915 KTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFED 5094
TK+ WPN I +DYT D +Y+AD+ L +I++ + +G R V + + HP A+ IFED
Sbjct: 658 STKLEWPNGITIDYTNDLLYWADAHLGYIEYSDLEGHHRHTVYDGA--LPHPFAITIFED 715
Query: 5095 MMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTN--PC 5268
+Y++D + ++ KY +G+ + +T + + HP QP++ +NPC TN C
Sbjct: 716 TIYWTDWNTRTVEKGNKY-DGSNRQTLVNTTHRPFDIHVYHPYRQPIV-SNPCGTNNGGC 773
Query: 5269 SHLCLLN-NKNTFTCKCP 5319
SHLCL+ FTC+CP
Sbjct: 774 SHLCLIKPGGKGFTCECP 791
Score = 343 bits (881), Expect = 5e-92
Identities = 302/1152 (26%), Positives = 460/1152 (39%), Gaps = 167/1152 (14%)
Frame = +1
Query: 2401 SMSFDWISKQLYYVDNIRNSLEVVKI-GETGLVHPDELVRRQLITELRDPVSVVVHPWKG 2577
S++ DW+S++LY++D + L V + G + V +P + +HP G
Sbjct: 571 SLAVDWVSRKLYWLDARLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLALHPQYG 630
Query: 2578 LLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMD 2757
L++A+ A I R +DG N VI +T L P+ + ID+ + L W D L I D
Sbjct: 631 YLYWADWGHRAYIGRVGMDGTNKSVIISTKLEWPNGITIDYTNDLLYWADAHLGYIEYSD 690
Query: 2758 FDGKNVVKL-DIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERS 2934
+G + + D P P AITI + IY+ ++ + +K +G + +
Sbjct: 691 LEGHHRHTVYDGALPHPFAITIFEDTIYWTDWNTRTVEKGNKYDGSNRQTLVN---TTHR 747
Query: 2935 IFSLKACSHQNQPIPDDSREHPCRASQ--CTQLCFATPSESHPNELEAKCACRQGFMINK 3108
F + QPI + PC + C+ LC P C C F
Sbjct: 748 PFDIHVYHPYRQPIVSN----PCGTNNGGCSHLCLIKPGGKG-----FTCECPDDF---- 794
Query: 3109 ENNHSCQKDPAEKIEQLCSSNSTQFQCKNG-RCIPKEWKCDGENDCLDESDEIDEKGDKC 3285
+ Q + +CSS TQF C N +CIP WKCDG+ DC D SDE+
Sbjct: 795 ---RTLQLSGSTYCMPMCSS--TQFLCANNEKCIPIWWKCDGQKDCSDGSDEL-----AL 844
Query: 3286 FHETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDN 3465
+ C +C + C Q C++ C + ++QC N
Sbjct: 845 CPQRFCRLGQFQCSDGN-CTSPQTLCNAHQNCPDGSDEDRLLCENHH---CDSNEWQCAN 900
Query: 3466 HRCIPEQWKXXXXXXXXXXXXEKLEMCGNATCAANQFSCANGRCIPIYWLCDGDNDCYDG 3645
RCIPE W+ E C + TC QF CANGRCIP W CD DNDC D
Sbjct: 901 KRCIPESWQCDSFNDCEDNSDEDSSHCASRTCRPGQFRCANGRCIPQAWKCDVDNDCGDH 960
Query: 3646 TDE-------------------------------------------DKERCPPVQCSAL- 3693
+DE D++ C C +
Sbjct: 961 SDEPIEECMSSAHLCDNFTEFSCKTNYRCIPKWAVCNGVDDCRDNSDEQGCEERTCHPVG 1020
Query: 3694 QFRCANGRQCVPLRNHXXXXXXXXXXXXXXXXAVTAESCTPDQFKCVSSGLCIPASWKXX 3873
FRC N C+PLR A CT +F+CV+ CIP+ W
Sbjct: 1021 DFRCKN-HHCIPLRWKCDGQNDCGDNSDEENCA--PRECTESEFRCVNQ-QCIPSRWICD 1076
Query: 3874 XXXXXXXXSDEPK-----------FGCTSGRQ---------------------------- 3936
+ + + F CTSG +
Sbjct: 1077 HYNDLWGDNSDERDCEMRTCHPEYFQCTSGHRVHSELKCDGSADCLDASDEADCPTRFPD 1136
Query: 3937 ---CSSDQFKCGNGRCILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACEND 4107
C + F+C N CI W CDG++DCGDGSDE N+ C+N+
Sbjct: 1137 GAYCQATMFECKNHVCIPPYWKCDGDDDCGDGSDEELHLCLDVPCNSP----NRFRCDNN 1192
Query: 4108 QETCIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCSFKCHNS---PNGPIC----- 4263
+ CI H++C+G C GTDE R +KC N P+ +C
Sbjct: 1193 R--CIYSHEVCNGVDDCGDGTDETEEHCRKPTPKPCTEYEYKCGNGHCIPHDNVCDDADD 1250
Query: 4264 -------------------------------------SCP--FGEQLVNKTKCEPENECL 4326
SC F + ++T C NEC
Sbjct: 1251 CGDWSDELGCNKGKERTCAENICEQNCTQLNEGGFICSCTAGFETNVFDRTSCLDINECE 1310
Query: 4327 DSSSCSQRCKDEKHGFTCSCDEGYELDVDK--RTCK---------VADNVKDTRIYVSNR 4473
+C Q C++ K + C C +G+ D+ + C + DNV+ + +S+
Sbjct: 1311 QFGTCPQHCRNTKGSYECVCADGFTSMSDRPGKRCAAEGSSPLLLLPDNVRIRKYNLSSE 1370
Query: 4474 NRIYYSDHKLDNWHTFGAIVENAIALAWD--SLTDRIYWSDIR---------EKKILSAN 4620
+S++ D + A+ WD + + + +R ++ +
Sbjct: 1371 R---FSEYLQDEEYI------QAVDYDWDPEDIGLSVVYYTVRGEGSRFGAIKRAYIPNF 1421
Query: 4621 RNGTNATVFIAD----GLDITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQ 4788
+G N V D + +GIA+DWVGR++YW D IEVA L D + R L+
Sbjct: 1422 ESGRNNLVQEVDLKLKYVMQPDGIAVDWVGRHIYWSDVKNKRIEVAKL-DGRYRKWLIST 1480
Query: 4789 NVSQPRGIAVDPRKGVMFWTDWGQNPCIERASMDGTDRQIIVKTKIYWPNTIALDY-TTD 4965
++ QP IAV+P+ G+MFWTDWG+ P +E A M+G D I+V + WP +++DY D
Sbjct: 1481 DLDQPAAIAVNPKLGLMFWTDWGKEPKLESAWMNGEDPNILVFEDLGWPTGLSIDYLNND 1540
Query: 4966 RVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPK 5145
R+Y++D K D I+ + YDG+ R + +K +P++L IFED +Y+ + +K +V+ +
Sbjct: 1541 RIYWSDFKEDVIETIKYDGTDRRVI---AKEAMNPYSLDIFEDQLYWISK--EKGEVWKQ 1595
Query: 5146 YPNGTTSEYPSHTFSKALGVVAV-HPVLQPVIKNNPCSTNPCSHLCLLNNKNTFTCKCPM 5322
G + + + L V + H + N C CSHLCLL ++C CP
Sbjct: 1596 NKFGQGKKEKTLVVNPWLTQVRIFHQLRYNKSVPNLCK-QICSHLCLL-RPGGYSCACPQ 1653
Query: 5323 GEK-LDASGKKC 5355
G ++ S +C
Sbjct: 1654 GSSFIEGSTTEC 1665
Score = 277 bits (709), Expect = 5e-72
Identities = 228/800 (28%), Positives = 326/800 (40%), Gaps = 119/800 (14%)
Frame = +1
Query: 82 SIQVDSPPSVRSRIISASVNTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXX 261
S Q DS S + AS C FRC +G+CI W
Sbjct: 907 SWQCDSFNDCEDNSDEDSSHCASRTCRPGQFRCANGRCIPQAWKCDVDNDCGDHSDE--- 963
Query: 262 PHPGCKSDQWQCDTYTWHSVS----CIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNV 429
P C S CD +T S CI ++ C+ + DC D SDE+ C T C
Sbjct: 964 PIEECMSSAHLCDNFTEFSCKTNYRCIPKWAVCNGVDDCRDNSDEQGCEERT--CHPVGD 1021
Query: 430 FMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCD 609
F C + C + KCDG+ DC D SDE++ R C + +FRC ++ QCI W+CD
Sbjct: 1022 FRCKN-HHCIPLRWKCDGQNDCGDNSDEENCAPRE---CTESEFRCVNQ-QCIPSRWICD 1076
Query: 610 ----------------------------------------GSKDCADGSDEPDTCEFK-- 663
GS DC D SDE D C +
Sbjct: 1077 HYNDLWGDNSDERDCEMRTCHPEYFQCTSGHRVHSELKCDGSADCLDASDEAD-CPTRFP 1135
Query: 664 ---KCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDE------------------------ 762
C A F+CKN C P ++CD DDCGD SDE
Sbjct: 1136 DGAYCQATMFECKNHVCIPPYWKCDGDDDCGDGSDEELHLCLDVPCNSPNRFRCDNNRCI 1195
Query: 763 ---------DECGEYR--------------CPPGKWNCPGTGHCIDQLKLCDGSKDCADG 873
D+CG+ C ++ C G GHCI +CD + DC D
Sbjct: 1196 YSHEVCNGVDDCGDGTDETEEHCRKPTPKPCTEYEYKC-GNGHCIPHDNVCDDADDCGDW 1254
Query: 874 ADEQQCS---QNLCPSLGCQAGCHPSPHGGE-CTCPSGYKLDDRFHRTCSDINECAEFGY 1041
+DE C+ + C C+ C GG C+C +G++ + +C DINEC +FG
Sbjct: 1255 SDELGCNKGKERTCAENICEQNCTQLNEGGFICSCTAGFETNVFDRTSCLDINECEQFGT 1314
Query: 1042 CDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVAR-REGLY 1218
C Q C N + + C C D FT M PGK C + + + L R Y
Sbjct: 1315 CPQHCRNTKGSYECVC-ADGFT-SMSDRPGKR-------CAAEGSSPLLLLPDNVRIRKY 1365
Query: 1219 RLNPKNPDEEVKKLASGEFIYGIDFDY-----GDRKIFWTDRLAHSAFSADV-------- 1359
L+ + E L E+I +D+D+ G +++T R S F A
Sbjct: 1366 NLSSERFSEY---LQDEEYIQAVDYDWDPEDIGLSVVYYTVRGEGSRFGAIKRAYIPNFE 1422
Query: 1360 DDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGL 1539
+ Q L LK ++ P +AVDW+ +Y + ++RI+V+ DG R L++ L
Sbjct: 1423 SGRNNLVQEVDLKLKYVMQPDGIAVDWVGRHIYWSDVKNKRIEVAKLDGRYRKWLISTDL 1482
Query: 1540 TLPLDIALDPLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHTHQVSGIVVD-ITAKRV 1707
P IA++P G MF+T+ + KLE+A M+G + LV +G+ +D + R+
Sbjct: 1483 DQPAAIAVNPKLGLMFWTDWGKEPKLESAWMNGEDPNILVFEDLGWPTGLSIDYLNNDRI 1542
Query: 1708 YWVDPKVDRLESIDYQGNDRRIVA-QGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKF 1884
YW D K D +E+I Y G DRR++A + MN P+ L +F+ LYW + V + KF
Sbjct: 1543 YWSDFKEDVIETIKYDGTDRRVIAKEAMN----PYSLDIFEDQLYWISKEKGEVWKQNKF 1598
Query: 1885 GSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDN 2064
G K N + + +H + + N C C +C+L
Sbjct: 1599 GQGKK--EKTLVVNPWLTQVRIFHQLR---------YNKSVPNLCKQI-CSHLCLLRPG- 1645
Query: 2065 GGFGVGYKCACPIGQKLVNG 2124
GY CACP G + G
Sbjct: 1646 -----GYSCACPQGSSFIEG 1660
Score = 275 bits (702), Expect = 3e-71
Identities = 210/763 (27%), Positives = 308/763 (39%), Gaps = 115/763 (15%)
Frame = +1
Query: 157 CNEN-DFRCNDGKCIRTEWXXXXXXXXXXXXXXXXX--PHPGCKSDQWQCDTYTWHSVSC 327
CN +F CN+ +CI E+ P C+S +C +S C
Sbjct: 76 CNATTEFMCNNRRCIPREFICNGVDNCHDNNTSDEKNCPDRTCQSGYPKCH----NSNIC 131
Query: 328 IAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLS 507
I CD DC D SDE +T CSS F CA GR CD + DC D S
Sbjct: 132 IPRVYLCDGDNDCGDNSDENPTYCTTHTCSSSE-FQCASGRCIPQTFGICDQETDCFDAS 190
Query: 508 DEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDE--------------- 642
DE SC + C +F+C D +CI W+CDG DC D SDE
Sbjct: 191 DEPSSCGHSERTCLSDEFKC-DGGRCIPNEWICDGDNDCGDMSDEDKRHQCQNQNCSDSE 249
Query: 643 --------PD------------------------TCEFKKCTANEFQCKNKRCQPRKFRC 726
PD C + C+ NEF C C P+ FRC
Sbjct: 250 FPCVNDRPPDRRCIPQSWPPDGDVDCTDGHDEIQNCTRRTCSENEFTCGYGLCIPKIFRC 309
Query: 727 DYYDDCGDNSDE------------------------------DECG-------------E 777
D ++DCGD SDE ++CG E
Sbjct: 310 DRHNDCGDYSDERGCLYQTCQQNQFTCQNGRCISKTFVCDEDNDCGDGSDELMHLCHTPE 369
Query: 778 YRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLC--PSL-GCQAGCHPSPH 948
CPP ++ C G CI+ +KLC+ DC D +DE+ C N C PS+ GC C +
Sbjct: 370 PTCPPHEFKC-DNGRCIEMMKLCNHLDDCLDNSDEKGCGINECHDPSISGCDHNCTDTLT 428
Query: 949 GGECTCPSGYKL-DDRFHRTCSDINECAEFGY-CDQLCANHRPGFTCSCLGDCFTLQMEH 1122
C+C GYKL D+ RTC DI+EC E + C Q C N + C C + + +
Sbjct: 429 SFYCSCRPGYKLMSDK--RTCVDIDECTEMPFVCSQKCENVIGSYICKC-APGYLREPDG 485
Query: 1123 GPGKDNLTMRGYCVSNNADKMKLFVARREG-LYRLNPKNPDEEVKKLASGEFIYGIDFDY 1299
+ N + Y + +N ++ +G Y L + D + +DFD
Sbjct: 486 KTCRQNSNIEPYLIFSNRYYLRNLTI--DGYFYSLILEGLDN----------VVALDFDR 533
Query: 1300 GDRKIFWTD---RLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIES 1470
+++++W D ++ F + E I+ L LAVDW++ LY +++
Sbjct: 534 VEKRLYWIDTQRQVIERMFLNKTNKETIINH-------RLPAAESLAVDWVSRKLYWLDA 586
Query: 1471 GSRRIDVSSYDGERRTVLLADGLTL--------PLDIALDPLRGEMFFT---NQLKLEAA 1617
+ VS +G R +L + P +AL P G +++ ++ +
Sbjct: 587 RLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLYWADWGHRAYIGRV 646
Query: 1618 AMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVV 1797
MDGTN+ +++T +GI +D T +YW D + +E D +G+ R V G +
Sbjct: 647 GMDGTNKSVIISTKLEWPNGITIDYTNDLLYWADAHLGYIEYSDLEGHHRHTVYDG--AL 704
Query: 1798 PHPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGP 1977
PHPF + +F+ +YWTDW V + K+ + NT + P I YHP QP
Sbjct: 705 PHPFAITIFEDTIYWTDWNTRTVEKGNKYDGSNRQTLVNTTHR--PFDIHVYHPYRQP-- 760
Query: 1978 GQSECLAMKIENPC--TNADCEGMCILSKDNGGFGVGYKCACP 2100
+ NPC N C +C++ G G+ C CP
Sbjct: 761 --------IVSNPCGTNNGGCSHLCLIKPG----GKGFTCECP 791
Score = 149 bits (375), Expect = 3e-33
Identities = 108/339 (31%), Positives = 145/339 (41%), Gaps = 21/339 (6%)
Frame = +1
Query: 172 FRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAEYQRCD 351
F C++G+CI EW C +T + C+ RCD
Sbjct: 1 FTCSNGRCISEEWKCDNDNGCGDGSDEMESV---CALHTCSPTAFTCANGRCVQYSYRCD 57
Query: 352 NITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRD--LSDEKDSC 525
DC DGSDE C DC++ FMC + R+C C+G +C D SDEK+
Sbjct: 58 YYNDCGDGSDETGCLFR--DCNATTEFMC-NNRRCIPREFICNGVDNCHDNNTSDEKNCP 114
Query: 526 SRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDE-PDTCEFKKCTANEFQCKNKR 702
R C +C + CI + ++CDG DC D SDE P C C+++EFQC + R
Sbjct: 115 DR---TCQSGYPKCHNSNICIPRVYLCDGDNDCGDNSDENPTYCTTHTCSSSEFQCASGR 171
Query: 703 CQPRKFR-CDYYDDCGDNSDE-DECG--EYRCPPGKWNCPGTGHCIDQLKLCDGSKDCAD 870
C P+ F CD DC D SDE CG E C ++ C G G CI +CDG DC D
Sbjct: 172 CIPQTFGICDQETDCFDASDEPSSCGHSERTCLSDEFKCDG-GRCIPNEWICDGDNDCGD 230
Query: 871 GADE--------QQCSQNLCPSLGCQ---AGCHPS--PHGGECTCPSGY-KLDDRFHRTC 1008
+DE Q CS + P + + C P P G+ C G+ ++ + RTC
Sbjct: 231 MSDEDKRHQCQNQNCSDSEFPCVNDRPPDRRCIPQSWPPDGDVDCTDGHDEIQNCTRRTC 290
Query: 1009 SDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHG 1125
S+ +G C F C DC E G
Sbjct: 291 SENEFTCGYGLCIPKI------FRCDRHNDCGDYSDERG 323
Score = 148 bits (373), Expect = 4e-33
Identities = 103/338 (30%), Positives = 142/338 (41%), Gaps = 23/338 (6%)
Frame = +1
Query: 157 CNENDFRCNDGKCI--RTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCI 330
C F+C+DG C +T + C S++WQC + CI
Sbjct: 850 CRLGQFQCSDGNCTSPQTLCNAHQNCPDGSDEDRLLCENHHCDSNEWQCA-----NKRCI 904
Query: 331 AEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSD 510
E +CD+ DC D SDE ++ C F CA+GR C + KCD DC D SD
Sbjct: 905 PESWQCDSFNDCEDNSDEDSSHCASRTCRPGQ-FRCANGR-CIPQAWKCDVDNDCGDHSD 962
Query: 511 EK-DSCSRNHTACFQY-QFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKC-TANE 681
E + C + C + +F C +CI K VC+G DC D SDE CE + C +
Sbjct: 963 EPIEECMSSAHLCDNFTEFSCKTNYRCIPKWAVCNGVDDCRDNSDEQG-CEERTCHPVGD 1021
Query: 682 FQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKD 861
F+CKN C P +++CD +DCGDNSDE+ C C ++ C CI +CD D
Sbjct: 1022 FRCKNHHCIPLRWKCDGQNDCGDNSDEENCAPRECTESEFRCVNQ-QCIPSRWICDHYND 1080
Query: 862 C-ADGADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRF----HRTCSDINEC 1026
D +DE+ C C H C SG+++ C D ++
Sbjct: 1081 LWGDNSDERDCEMRTC-------------HPEYFQCTSGHRVHSELKCDGSADCLDASDE 1127
Query: 1027 AEF-------GYCDQL---CANH---RPGFTCSCLGDC 1101
A+ YC C NH P + C DC
Sbjct: 1128 ADCPTRFPDGAYCQATMFECKNHVCIPPYWKCDGDDDC 1165
Score = 143 bits (361), Expect = 1e-31
Identities = 83/232 (35%), Positives = 118/232 (50%), Gaps = 3/232 (1%)
Frame = +1
Query: 412 CSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQ 591
CSS F+CA+ +C + KCDG+ DC D SDE C + C QF+C+D C
Sbjct: 809 CSSTQ-FLCANNEKCIPIWWKCDGQKDCSDGSDELALCPQRF--CRLGQFQCSD-GNCTS 864
Query: 592 KSWVCDGSKDCADGSDEPD-TCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDED- 765
+C+ ++C DGSDE CE C +NE+QC NKRC P ++CD ++DC DNSDED
Sbjct: 865 PQTLCNAHQNCPDGSDEDRLLCENHHCDSNEWQCANKRCIPESWQCDSFNDCEDNSDEDS 924
Query: 766 -ECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPS 942
C C PG++ C G CI Q CD DC D +DE P C + H
Sbjct: 925 SHCASRTCRPGQFRC-ANGRCIPQAWKCDVDNDCGDHSDE--------PIEECMSSAHLC 975
Query: 943 PHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGD 1098
+ E +C + Y+ ++ C+ +++C + +Q C TC +GD
Sbjct: 976 DNFTEFSCKTNYRCIPKW-AVCNGVDDCRD-NSDEQGCEER----TCHPVGD 1021
Score = 142 bits (357), Expect = 3e-31
Identities = 81/224 (36%), Positives = 116/224 (51%), Gaps = 7/224 (3%)
Frame = +1
Query: 268 PGCKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDEKD-CPASTVDCSSQNVFMCAD 444
P C S Q+ C ++ CI + +CD DC+DGSDE CP F C+D
Sbjct: 807 PMCSSTQFLCA----NNEKCIPIWWKCDGQKDCSDGSDELALCPQRFCRLGQ---FQCSD 859
Query: 445 GRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDC 624
G C C+ +C D SDE NH C +++CA+K +CI +SW CD DC
Sbjct: 860 G-NCTSPQTLCNAHQNCPDGSDEDRLLCENH-HCDSNEWQCANK-RCIPESWQCDSFNDC 916
Query: 625 ADGSDEPDT-CEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDE--DEC--GEYRCP 789
D SDE + C + C +F+C N RC P+ ++CD +DCGD+SDE +EC + C
Sbjct: 917 EDNSDEDSSHCASRTCRPGQFRCANGRCIPQAWKCDVDNDCGDHSDEPIEECMSSAHLCD 976
Query: 790 P-GKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLG 918
+++C CI + +C+G DC D +DEQ C + C +G
Sbjct: 977 NFTEFSCKTNYRCIPKWAVCNGVDDCRDNSDEQGCEERTCHPVG 1020
Score = 138 bits (348), Expect = 3e-30
Identities = 120/426 (28%), Positives = 156/426 (36%), Gaps = 66/426 (15%)
Frame = +1
Query: 8242 DDIGLAASKVQC---SCNDTYELVQEPGKDYPTQCVLRG------SNSEPAKECLPPYNF 8394
+D G + + C CN T E + + P + + G +N+ K C P
Sbjct: 60 NDCGDGSDETGCLFRDCNATTEFMCNNRRCIPREFICNGVDNCHDNNTSDEKNC-PDRTC 118
Query: 8395 QCG------DGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCI-DSAK 8553
Q G CI CD DC D SDENP YC T +C C + RCI +
Sbjct: 119 QSGYPKCHNSNICIPRVYLCDGDNDCGDNSDENPTYCTTHTCSSSEFQCASGRCIPQTFG 178
Query: 8554 KCNHIDDCGDGSDELDC--PSAVACAEGTFPCSNGHCINQTKVCDGHNDCHD-------- 8703
C+ DC D SDE S C F C G CI +CDG NDC D
Sbjct: 179 ICDQETDCFDASDEPSSCGHSERTCLSDEFKCDGGRCIPNEWICDGDNDCGDMSDEDKRH 238
Query: 8704 ----EQVSDESLATCPGLPIDCRGVKVRCP-----------------------------N 8784
+ SD P D R + P
Sbjct: 239 QCQNQNCSDSEFPCVNDRPPDRRCIPQSWPPDGDVDCTDGHDEIQNCTRRTCSENEFTCG 298
Query: 8785 TNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCIPETWQCDGDNDCSD 8964
+CI CD ++DCGD +DE C+ Q C Q+ C +GRCI +T+ CD DNDC D
Sbjct: 299 YGLCIPKIFRCDRHNDCGDYSDERG--CLYQTCQQNQFTCQNGRCISKTFVCDEDNDCGD 356
Query: 8965 GWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXXXXXXHSRHGCGNRT 9144
G DE C + C + F+CDN +CI + GCG
Sbjct: 357 GSDELMHLC--HTPEPTC-PPHEFKCDNGRCIE---MMKLCNHLDDCLDNSDEKGCGINE 410
Query: 9145 CTDQ-----EFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECNK- 9306
C D + +CT L C P L TC DE TE+ ++C
Sbjct: 411 CHDPSISGCDHNCTDT--LTSFYCSCRPGYKLMSDKRTCV-DIDECTEMPFVCSQKCENV 467
Query: 9307 -GEFRC 9321
G + C
Sbjct: 468 IGSYIC 473
Score = 103 bits (257), Expect = 1e-19
Identities = 84/336 (25%), Positives = 152/336 (45%), Gaps = 12/336 (3%)
Frame = +1
Query: 6313 CTCANGYVK--DGQTSCKLFD-ESFVIVATKTKVIGYPIDETQSKGVAMEPIGGLSITGV 6483
C CA GY++ DG+T + + E ++I + + + ID + +E + ++ +
Sbjct: 473 CKCAPGYLREPDGKTCRQNSNIEPYLIFSNRYYLRNLTIDG-YFYSLILEGLD--NVVAL 529
Query: 6484 DYDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINYNMYFIN 6663
D+D K +Y + + I + +++ +I + + +SLA+DW++ +Y++
Sbjct: 530 DFDRVEKRLYWIDTQ--RQVIERMFLNKTNKETIINHRLPAA--ESLAVDWVSRKLYWL- 584
Query: 6664 HDAERTNIEVSKLDGTYRKILL--------TTKTETPSSIAVDPVSRYLYWADQGQKPTI 6819
DA + VS L+G +R++L T + P +A+ P YLYWAD G + I
Sbjct: 585 -DARLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLYWADWGHRAYI 643
Query: 6820 QRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPELVRSD- 6996
R +DG+ + VI+S+ + P + +D + ++YW+DA + I G V
Sbjct: 644 GRVGMDGTNKSVIISTKLEWPNGITIDYTNDLLYWADAHLGYIEYSDLEGHHRHTVYDGA 703
Query: 6997 IASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNN 7176
+ + + +YWTD R K N+ T V + + D+ V+
Sbjct: 704 LPHPFAITIFEDTIYWTDWNT----RTVEKGNKYDGSNRQTLVNTTHRPF-DIHVYHPYR 758
Query: 7177 QPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSC 7284
QP S+PC C+ LC PG + TC C
Sbjct: 759 QPIVSNPC----GTNNGGCSHLCLIKPGGKGFTCEC 790
Score = 102 bits (255), Expect = 2e-19
Identities = 74/300 (24%), Positives = 136/300 (44%), Gaps = 18/300 (6%)
Frame = +1
Query: 6472 ITGVDYDYESKTI------YVAEASGINKGIT--AYTIGESSPRAVIRDSIGSLTIK--- 6618
I VDYD++ + I Y G G AY S R + + L +K
Sbjct: 1382 IQAVDYDWDPEDIGLSVVYYTVRGEGSRFGAIKRAYIPNFESGRNNLVQEV-DLKLKYVM 1440
Query: 6619 ---SLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLY 6789
+A+DW+ ++Y+ D + IEV+KLDG YRK L++T + P++IAV+P ++
Sbjct: 1441 QPDGIAVDWVGRHIYW--SDVKNKRIEVAKLDGRYRKWLISTDLDQPAAIAVNPKLGLMF 1498
Query: 6790 WADQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVD-VASKMIYWSDAKMDGIYRVRST 6966
W D G++P ++ ++++G ++V + PT L +D + + IYWSD K D I ++
Sbjct: 1499 WTDWGKEPKLESAWMNGEDPNILVFEDLGWPTGLSIDYLNNDRIYWSDFKEDVIETIKYD 1558
Query: 6967 GGTPELVRSDIASAAGVALHGQNMYWTDNRLEKLFRAT---SKPNQTSLLLSPTTVAASL 7137
G ++ + + + + +YW ++++ + +L+++P
Sbjct: 1559 GTDRRVIAKEAMNPYSLDIFEDQLYWISKEKGEVWKQNKFGQGKKEKTLVVNPW------ 1612
Query: 7138 KDIGDVAVFSSNNQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCARGVLKGRTCE 7317
+ V +F ++ NL K C+ LC PG + C ++G T E
Sbjct: 1613 --LTQVRIFHQLRYNKS------VPNLCKQICSHLCLLRPGGYSCACPQGSSFIEGSTTE 1664
Score = 78.2 bits (191), Expect = 6e-12
Identities = 85/371 (22%), Positives = 146/371 (38%), Gaps = 10/371 (2%)
Frame = +1
Query: 5251 CSTNP--CSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDA--KPFLVIIQKTNVFGIEM 5418
C+ P CS C N ++ CKC G + GK C ++ +P+L+ + + + +
Sbjct: 453 CTEMPFVCSQKCE-NVIGSYICKCAPGYLREPDGKTCRQNSNIEPYLIFSNRYYLRNLTI 511
Query: 5419 NSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRST 5598
+ + L GL N +D + + ++ ++ T I R
Sbjct: 512 DGYFYS--------LILEGLDNVVALDFDRVEKRLYWID-----------TQRQVIERMF 552
Query: 5599 VNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVILS--ND 5772
+N NK + + +P A L DW R L + + + G R + +
Sbjct: 553 LNKTNKETIINHRLPA-AESLAVDWVSRKLYWLDARLDGLFVSDLNGGHRRMLAQHCVDA 611
Query: 5773 QSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIA 5952
+ GY++W D G A + R G+DG+N VI S L + I
Sbjct: 612 NNTFCFDNPRGLALHPQYGYLYWADWGHRAY---IGRVGMDGTNKSVIISTKLEWPNGIT 668
Query: 5953 IDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAFDSIE 6132
ID TN +Y+++A G I +G RH V P + + D +++ D ++E
Sbjct: 669 IDYTNDLLYWADAHLGYIEYSDLEGHHRHTVYDGALPHPFAITIFEDTIYWTDWNTRTVE 728
Query: 6133 VAT-INGDSQPP--QWTHFKKDVENLANIKALQPRASSSGHPCHINNGNCDHICIPLMFA 6303
+G ++ TH D+ + QP S +PC NNG C H+C+
Sbjct: 729 KGNKYDGSNRQTLVNTTHRPFDIHVYHPYR--QPIVS---NPCGTNNGGCSHLCLIKPGG 783
Query: 6304 QR-TCTCANGY 6333
+ TC C + +
Sbjct: 784 KGFTCECPDDF 794
Score = 63.2 bits (152), Expect = 2e-07
Identities = 83/370 (22%), Positives = 149/370 (39%), Gaps = 13/370 (3%)
Frame = +1
Query: 5287 NNKNTFTCKCPMG--EKLDASGKKCIDDAKPFLVIIQKTNVFGIEMNSASEKETPVLAGM 5460
N K ++ C C G D GK+C + L+++ NV + N +SE+ + L
Sbjct: 1321 NTKGSYECVCADGFTSMSDRPGKRCAAEGSSPLLLLPD-NVRIRKYNLSSERFSEYLQDE 1379
Query: 5461 VPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNGGNKT------K 5622
+ A D +D + ++ +T + A + +G N K
Sbjct: 1380 EYIQ----AVDYDWDPEDIGLSVVYYTVRGEGSRFGAIKRAYIPNFESGRNNLVQEVDLK 1435
Query: 5623 MFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVILSNDQSXXXXXXXX 5802
+ PD + DW GR++ + + IE+ + G+ YR ++S D
Sbjct: 1436 LKYVMQPDG---IAVDWVGRHIYWSDVKNKRIEVAKLDGR-YRKWLISTDLDQPAAIAVN 1491
Query: 5803 XXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAID-TTNTRVY 5979
G +FW D G + K+ A ++G +P ++ DL ++ID N R+Y
Sbjct: 1492 PKL-----GLMFWTDWG---KEPKLESAWMNGEDPNILVFEDLGWPTGLSIDYLNNDRIY 1543
Query: 5980 FSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAFDSIEVATINGDSQ 6159
+S+ K I ++ YDG DR V++ P L + D+L++ S E + ++
Sbjct: 1544 WSDFKEDVIETIKYDGTDRR-VIAKEAMNPYSLDIFEDQLYWI-----SKEKGEVWKQNK 1597
Query: 6160 PPQWTHFKKDVEN--LANIKALQPRASSSGHPCHINNGNCDHICIPLMFAQRTCTCANG- 6330
Q K V N L ++ + P ++ C H+C+ L +C C G
Sbjct: 1598 FGQGKKEKTLVVNPWLTQVRIFHQLRYNKSVP-NLCKQICSHLCL-LRPGGYSCACPQGS 1655
Query: 6331 -YVKDGQTSC 6357
+++ T C
Sbjct: 1656 SFIEGSTTEC 1665
Score = 63.2 bits (152), Expect = 2e-07
Identities = 45/166 (27%), Positives = 71/166 (42%)
Frame = +1
Query: 2980 DDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINKENNHSCQKDPAEKIEQL 3159
D+ + H C+ C+ F ++ P+ + ++ + H + +
Sbjct: 233 DEDKRHQCQNQNCSDSEFPCVNDRPPDRRCIPQSWPPDGDVDCTDGHD---EIQNCTRRT 289
Query: 3160 CSSNSTQFQCKNGRCIPKEWKCDGENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKK 3339
CS N +F C G CIPK ++CD NDC D S DE+G C ++T C +N C+N +
Sbjct: 290 CSEN--EFTCGYGLCIPKIFRCDRHNDCGDYS---DERG--CLYQT-CQQNQFTCQN-GR 340
Query: 3340 CIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNHRCI 3477
CI + C +P C +F+CDN RCI
Sbjct: 341 CISKTFVCDEDNDCGDGSDELMHLCHT-PEPTCPPHEFKCDNGRCI 385
>gi|31239543|ref|XP_320185.1| ENSANGP00000011153 [Anopheles gambiae]
gi|30174007|gb|EAA00393.2| ENSANGP00000011153 [Anopheles gambiae str.
PEST]
Length = 4569
Score = 1031 bits (2667), Expect = 0.0
Identities = 767/2719 (28%), Positives = 1216/2719 (44%), Gaps = 127/2719 (4%)
Frame = +1
Query: 5887 GLDGSNPLVI---ASNDLAELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLS-- 6051
GL N LV+ +++ +D +A+D R+Y+ + AG I+ VL+
Sbjct: 1582 GLSVVNSLVVYPTSNSTFHPIDSLALDFETNRLYYISSNAGEINYYDIGSGKIIQVLAPH 1641
Query: 6052 DGGRQPNGLAFYGDRLFYADSAFDSIEVATINGDSQPPQWTHFKKDVENLANIKALQPRA 6231
+ + + Y D ++Y D+ I N P + + L I+ P A
Sbjct: 1642 EDNHPISTITIYRDSIYYDDNHDGRIMRCNKNLCQNP---VSVRNNTSGLNAIRMYHPGA 1698
Query: 6232 SSSGHPCHINNGN-----CDHICIPLMFAQRTCTCANGYVKDGQTSCKLFD-ESFVIVAT 6393
S + C N C+H+CIP+ C CA GY D + + + ++ +
Sbjct: 1699 QSGTNSCQKRNDKSAGTGCEHLCIPVSAQSHVCRCAIGYRSDPRNPWRCIGLDDILVYSV 1758
Query: 6394 KTKVIGYPI---DETQSKGVAMEPIGGLS----ITGVDYDYESKTIYVAEASGINKGITA 6552
++ G + DE+ E +G L T +D+D +Y+A+ ++G
Sbjct: 1759 GHQLKGIALSSSDESTGSLRNRESLGPLQQISLATSIDFDVAHDYVYIADT---DRGSIT 1815
Query: 6553 YTIGESSPRAVIRDSIGSLT-------IKSLAIDWINYNMYFINHDAERTNIEVSKLDGT 6711
+ S R VI + + + +AIDW+ N+Y+ D +R IEV++L+GT
Sbjct: 1816 RIKRDGSAREVIISNFEQVVDGSTLDWLGGIAIDWVAENIYWT--DQKRNLIEVARLNGT 1873
Query: 6712 YRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQRSFLDGSRREVIVSSGIAEPTDL 6891
R ++ + E+P +A+DP+ YL++ +G TI R LDGS ++V+ A +DL
Sbjct: 1874 LRYVV-ASDVESPQLLAIDPIQGYLFYVTRG---TIGRMGLDGSGNFILVNRSSAI-SDL 1928
Query: 6892 VVDVASKMIYWSDAKMDGIYRVRSTGGTPELVRSDIA-SAAGVALHGQNMYWTDNR---- 7056
+D+ ++++YW + D I++V G L+ + + + + L G ++YW D+R
Sbjct: 1929 ALDLDNQVVYWCETSTDTIWKVDYDGNLKRLLLNGTSHNPKSLDLFGDSIYWADSRGNIY 1988
Query: 7057 ---LEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRASSPCQITDNLRKS 7227
L +F S A + + D+ VFSS Q + ++ C +++
Sbjct: 1989 EAGLSNIFNYRS-----------VVEALEVSSLKDIKVFSSRKQSKTNA-CGVSNG---- 2032
Query: 7228 PCTQLCFATPGTQTPTCSCARGVLKG---RTCEEPDTYIMFSDGDKIIDVAIEPDVKASR 7398
C +LC GT P C+C+ G + +TCE + +++FS I + + +
Sbjct: 2033 GCQELCLFN-GTH-PICACSHGKISSADLKTCEPYENFLIFSRQSAIESIHMTD----AN 2086
Query: 7399 PLKDPFPEISNLQ------TFDVDVNLRRVYFVVESPVGVNISWFSMNNAENPRLVFGAS 7560
+ P PEI N D + +++ +N +F N + R+V
Sbjct: 2087 NINGPIPEIKNSSYLKNTIALSYDYEQQLIFYSDIDHSTINCVFF--NGTNHRRIV---- 2140
Query: 7561 KQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTIASG----------- 7707
K++ + + + LT+ +++T+ + ++D L+ A+
Sbjct: 2141 ----TKQLT-VEGLAFNVLTRVLFWTSNNEAAIRSLDLNKASLTDPAANAELVQDVIKLR 2195
Query: 7708 --DWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIA 7881
D +A++PC +++W T+ + I+R+ +G + I++ I +P A+
Sbjct: 2196 ATDKPRGIAVEPCLAMVYW------TNWNQHAASIQRAYPSGYGLESIITSDIQMPNALT 2249
Query: 7882 VDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGYRAK--SLDIWDRWLYMSDPLSNGVF 8055
+D++ +K+YWAD +E DYDG++R V+A +L ++ L+ +D + V
Sbjct: 2250 LDYQARKLYWADALLDKVERTDYDGKHRVVLAHSTPKHPFALAVFGDLLFWTDLTVHAVI 2309
Query: 8056 RIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLCTV 8235
R +K SGS + V+ R I + + A + Q+ ++ C+ NG C+ +C +
Sbjct: 2310 RANKYSGSDI--VLLRRDIAQPMGIVAVQ-------QIDKECSADPCQVMNGFCEDVCLI 2360
Query: 8236 VADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSEPAKECLPPYNFQCGDGSC 8415
A A KV+C C T ++ G+ + V S+SE F C +G+C
Sbjct: 2361 DA------AGKVECHC--TQGVLAADGQRCIPKSVSNCSSSE----------FSCTNGNC 2402
Query: 8416 ILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHIDDCGDGSDE 8595
I TCD +C D SDE +C R CP+ + C N RCI ++CNHI +CGDGSDE
Sbjct: 2403 IPFHLTCDGVKNCLDGSDELVTFCAHRPCPDGFFRCNNARCIPKNQQCNHIQNCGDGSDE 2462
Query: 8596 LDCPSAVACAEGT-FPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPGLPIDCRGVKV 8772
+ C +C T F C++G CI ++ CD DC D VSDE CP + +C V
Sbjct: 2463 VGC----SCNNATHFRCTDGQCIVKSMRCDYEPDCKD--VSDE--IGCPVMR-NCTEGFV 2513
Query: 8773 RCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCIPETWQCDGDN 8952
C NT C P CDG +DC D +DE C + C +GRCIP++W+CD ++
Sbjct: 2514 NCANTTGCYMPTWRCDGENDCWDNSDEQDCPTAIPTCPEDKFLCANGRCIPQSWRCDDED 2573
Query: 8953 DCSDGWDETHTNCTDTAGKKICVGDYLFQCDNL-KCISRAFIXXXXXXXXXXXXXHSRHG 9129
DC+D ++ + A K C + F+C N +CIS ++
Sbjct: 2574 DCTDATGGGLSS-DELACVKHCKPNQ-FKCTNTSECISNSWQCDGHPDCADGSDEGDH-- 2629
Query: 9130 CGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECNKG 9309
C R C + EF C + + CIP+ W+CDG+V C +D+ + EC+K
Sbjct: 2630 CSRRDCPETEFQCPTTNR-------CIPQKWVCDGEVDCGATQDDEMGCDEMMVNECDKT 2682
Query: 9310 EFRCSNQHCIHSTWECDGDNDCLDGSDEHANCT----------------YSSCQPDFFQC 9441
F C N CI CDG+ DC+DGSDE C + +PD F+C
Sbjct: 2683 SFTCKNGECISLLHVCDGEQDCVDGSDEPLYCKEGDDGYDEEEGAGVDDHLCVEPDHFRC 2742
Query: 9442 ANHKCVPNSWKCDGNDDCEDGSDE--KDCPKNSASAQKASKCSNGQFQCTSGECIDDAKV 9615
N +C+ + C+ NDDC DGSDE + C + F+C SG CI +
Sbjct: 2743 NNGRCIERNLTCNVNDDCADGSDEDIRLCRNTTLIC-----AGPDLFRCESGACITSNML 2797
Query: 9616 CDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCH 9795
CD DC D SDE S C ++EC + LC +C D +GY+C C +GF ++++D+ C
Sbjct: 2798 CDGANDCGDWSDEKS-CQVNECEMIPD-LCAHECEDRPVGYECVCRKGFRVNVNDKHLCV 2855
Query: 9796 NVNECYEGISG-CSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYI 9972
+V+EC E C+Q C + GSY C C+DG+ L +D P + +N++Y+
Sbjct: 2856 DVDECTEQQPRPCTQTCVNTHGSYHCTCLDGFVLRDNDTCRAEGRHILPPKLIFSNRYYL 2915
Query: 9973 RKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETV 10152
R++ + G + A N ++LD D ++ Y D + + E E +
Sbjct: 2916 REVDLSGGM-TILAHNLTNAITLDFDWKDECYYWSDVTRTVTTVKRMCESGEENRPVEVI 2974
Query: 10153 LRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGK 10332
R N+ EG+AVDWVGR LY ++ +I V +LDGR+ + LI +Q+P+AI + P +
Sbjct: 2975 HRTNLKNPEGLAVDWVGRNLYWCDKGLDTIEVSKLDGRYRRVLINKELQKPRAIALDPYR 3034
Query: 10333 GYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLN 10512
Y+++T+W QP+IGR +DGS + L + LGWPNA+ I + +++LFWGDA +
Sbjct: 3035 RYMYWTDWGDQPHIGRAGMDGSNQTI-----LIKEQLGWPNALTISFETNQLFWGDARED 3089
Query: 10513 EIGFMDFDGNGRRHI------PAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNE 10674
I D DG R + P HV ++ V++D +YW+D + + + C K+ G
Sbjct: 3090 YIAVSDLDGQNVRILLSRARQPTLNLHHVFAIAVWEDRIYWSDLDSKSIEYCHKFRGDGC 3149
Query: 10675 TILKKTVQLPNDLRIVHPMRQ-PAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLL 10851
L T+ P D+R+ H RQ NPC + GC LC++ GY C CPD F+L
Sbjct: 3150 GTLINTIHRPMDIRVFHYYRQLQPEVNPC--DTAGCQTLCVLSPDPPGYRCLCPDNFILT 3207
Query: 10852 SDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQ 11031
+D K+C NC+ F C KCIP W CD + DC DGSDEP C C G+FQ
Sbjct: 3208 ADGKSCAANCSAAHFQCR-TTFKCIPFYWRCDKQDDCGDGSDEPPN--CPTFTCEAGQFQ 3264
Query: 11032 CTNHNCTRPFQIXXXXXXXXXXXXEQNCDK-ACDPWMFKCAATGRCIPRRFTXXXXXXXX 11208
C N C P QI E++CD+ C FKC +
Sbjct: 3265 CLNKRCINPSQICDGVDQCGDLSDERDCDRFECFSSHFKCGPSA---------------- 3308
Query: 11209 XRSDEADTLCMSAERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXETPECAQIECKKG 11388
+ C+ R C EE C N + + C C
Sbjct: 3309 --AKNTSGFCIEGARRCD-EEVNCPNGE-------------------DEQNCEPKNCTAT 3346
Query: 11389 WTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMCDT 11568
RC++ RCI C+ DC D SDE T EFRC+ G+CIP+ W+CD
Sbjct: 3347 QFRCANGGRCIDRTWVCDNVPDCHDGSDEQVCGPATTCPEHEFRCS-EGRCIPQSWLCDD 3405
Query: 11569 ENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTLRR 11748
E DC + DE + C + FRCN+ KCIPG CD C D DE C LR
Sbjct: 3406 EKDCANGEDETENCQKPEAITCEPTSFRCNNSKCIPGRWRCDFENDCGDNSDELNCELRN 3465
Query: 11749 CLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFEC-ANSVCIPRK 11925
C +C DG CI + CD + +C + +DE +C TCS +F+C ++ CI K
Sbjct: 3466 CSESEFRCRDGHCIRGIRRCDNEFNCADHSDEENC----NVTCSAEQFKCKSHPACISNK 3521
Query: 11926 FMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDE 12105
F SDE EC+ + +RC + + C+ +C+G +DC N SDE
Sbjct: 3522 FKCDGDNDCIDESDEEDCECQEGE------YRCNNGK-CILSSWVCDGIDDCLDN--SDE 3572
Query: 12106 HLSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAF 12285
C E+G C+ F+CAN C+ ++ CD KDDCGD SDE H K +F
Sbjct: 3573 MGEYC---KEHG-CNKRAFRCANRNCIRKSLMCDNKDDCGDNSDEKSALCH--KCPPNSF 3626
Query: 12286 GNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGSYLC 12465
N K I +R HC D E I G C+QLC+ KG Y C
Sbjct: 3627 RCNSDSKCIDIALRCDQTPHCLD-------ESDEIGCIKTGCGFGACSQLCIEKKGHYTC 3679
Query: 12466 RCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGSGTNRHXXXXXXXXXX 12645
RC E Y V G C A + +++ ++ L + T
Sbjct: 3680 RCAEGY---VKGGPGRNATCVAVDEQGILLVASESDFRSLY---ADTPVMGYLQTSSLKI 3733
Query: 12646 XXXXXXXXPRKELMYWIDGSERTIYR----SAIANG---NQSHEGQKLDVDFAAMGVVPT 12804
++WID + +I + + + +G ++S K + +G P
Sbjct: 3734 DRFDFAITRHNITLFWIDSYDTSINKILMDTTVKDGGDYSRSPPVDKRKIVRRGLGPAPA 3793
Query: 12805 AIAVD--YTTGNLFIAAVSENIENGLVTARKKRMSEP--IDNQNTGFIFVCLPDGRYLKK 12972
+ D T + V ++ E + ++E + N+ IFV +G
Sbjct: 3794 PPSYDRIKTLDGKHSSVVLKDDEIHPIAIACDWLTERLYVINKKRSNIFVMSFNGTNHTT 3853
Query: 12973 IVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDE 13152
+ A + P L+ P +G + +S + I + MDG +Q +V V + +AID
Sbjct: 3854 LTATG-KHPIDLVVDPVSGMMVWS---IMETIISSGMDGRGKQKLVHTNVEWASGLAIDT 3909
Query: 13153 GKGNRIYWVDPKYRRVD-AVNIDGSERTTV--VHDRHIPYAVDVFENHIYWLSRESKTLY 13323
R+YW D + ++ + + G +R + +HD P +DVFE+ +Y + L
Sbjct: 3910 -TTKRLYWADYRKSTIETCLLLTGGDRHVIAELHDYSKPKLLDVFEDSVYVILYNQNILK 3968
Query: 13324 VQDKFGR--------------GRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCS 13461
+ +K+GR G +SD+ H + K + + C + C
Sbjct: 3969 L-NKYGRDNGTYMNEEARGAGGLAGYRSSDVHFIHPL-------KHDRSVPNPCIISPCH 4020
Query: 13462 HLCVSLPST----GFACLCPDGIVPQLDGSCATQHVEALTMPKQ---CKC-TNGGKCRLD 13617
+ V L ST AC+CPD P++ + E L +P Q CK N G C +D
Sbjct: 4021 NSTVCLLSTVSRLKRACVCPDA-RPRIVFDERGEVKECLDLPAQAPECKLHCNNGTCFID 4079
Query: 13618 ----GSCECTSDFEGDQCE 13662
C+C++ F+G C+
Sbjct: 4080 TDGQQKCKCSASFDGKYCD 4098
Score = 442 bits (1136), Expect = e-121
Identities = 403/1628 (24%), Positives = 667/1628 (40%), Gaps = 133/1628 (8%)
Frame = +1
Query: 871 GADEQQCSQNLCPSLGCQAGCHP-SPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCD 1047
G + Q + GC+ C P S C C GY+ D R C +++ +
Sbjct: 1701 GTNSCQKRNDKSAGTGCEHLCIPVSAQSHVCRCAIGYRSDPRNPWRCIGLDDILVYSVGH 1760
Query: 1048 QLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLN 1227
QL +G +S++ D+ + RE L L
Sbjct: 1761 QL--------------------------------KGIALSSS-DESTGSLRNRESLGPLQ 1787
Query: 1228 PKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKS 1407
+ + + +++Y D D G D A ++ + + S + L
Sbjct: 1788 QISLATSIDFDVAHDYVYIADTDRGSITRIKRDGSAREVIISNFEQVVDGSTLDWLG--- 1844
Query: 1408 LVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMF 1587
+A+DW+ +Y + I+V+ +G R V+ +D + P +A+DP++G +F
Sbjct: 1845 -----GIAIDWVAENIYWTDQKRNLIEVARLNGTLRYVVASD-VESPQLLAIDPIQGYLF 1898
Query: 1588 FTNQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDR 1767
+ + + +DG+ LVN + +S + +D+ + VYW + D + +DY GN +
Sbjct: 1899 YVTRGTIGRMGLDGSGNFILVN-RSSAISDLALDLDNQVVYWCETSTDTIWKVDYDGNLK 1957
Query: 1768 RIVAQGMNVVPHPFGLALFDQYLYWTD-------------WTRLGVIQVEKFGS--DTKL 1902
R++ G + +P L LF +YW D + V++ + S D K+
Sbjct: 1958 RLLLNGTS--HNPKSLDLFGDSIYWADSRGNIYEAGLSNIFNYRSVVEALEVSSLKDIKV 2015
Query: 1903 LWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVG 2082
S ++ G+S N C+ +C+ + G
Sbjct: 2016 FSSRKQSKTNACGVS-------------------------NGGCQELCLFN------GTH 2044
Query: 2083 YKCACPIGQ-KLVNGKRCIDSIDYLLFSSNKIVRGIFPEINEKALAEAVLPISPISQRRI 2259
CAC G+ + K C ++L+FS + I + +A PI + +
Sbjct: 2045 PICACSHGKISSADLKTCEPYENFLIFSRQSAIESIH-------MTDANNINGPIPEIKN 2097
Query: 2260 GMYFE----VECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWISK 2427
Y + + D FY+DI +TI + +G + VT + ++F+ +++
Sbjct: 2098 SSYLKNTIALSYDYEQQLIFYSDIDHSTINCVFFNGTNHRRI-VTKQLTVEGLAFNVLTR 2156
Query: 2428 QLYYVDNIRNSLEVVKIGETGLVHPD---ELVRRQLITELRD-PVSVVVHPWKGLLFYAE 2595
L++ N ++ + + + L P ELV+ + D P + V P ++++
Sbjct: 2157 VLFWTSNNEAAIRSLDLNKASLTDPAANAELVQDVIKLRATDKPRGIAVEPCLAMVYWTN 2216
Query: 2596 AMRPAA-IYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKN 2772
+ AA I R + G + I + + P+ + +D+ +L W D LL + D+DGK+
Sbjct: 2217 WNQHAASIQRAYPSGYGLESIITSDIQMPNALTLDYQARKLYWADALLDKVERTDYDGKH 2276
Query: 2773 VVKLDIDNPI-PVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSL- 2946
V L P P A+ + + +++ +++ R +K +G ++R A I ++
Sbjct: 2277 RVVLAHSTPKHPFALAVFGDLLFWTDLTVHAVIRANKYSGSDIVLLRRDIAQPMGIVAVQ 2336
Query: 2947 ---KACS-------------------------HQNQPI--PDDSREHPCRASQCTQLCFA 3036
K CS H Q + D R P S C+ F+
Sbjct: 2337 QIDKECSADPCQVMNGFCEDVCLIDAAGKVECHCTQGVLAADGQRCIPKSVSNCSSSEFS 2396
Query: 3037 TPSES----------------HPNELEAKCA---CRQGFMI---------NKENNH--SC 3126
+ + +EL CA C GF N++ NH +C
Sbjct: 2397 CTNGNCIPFHLTCDGVKNCLDGSDELVTFCAHRPCPDGFFRCNNARCIPKNQQCNHIQNC 2456
Query: 3127 QKDPAEKIEQLCSSNSTQFQCKNGRCIPKEWKCDGENDCLDESDEIDEKGDKCFHETECA 3306
D ++++ C+ N+T F+C +G+CI K +CD E DC D SDEI C C
Sbjct: 2457 G-DGSDEVGCSCN-NATHFRCTDGQCIVKSMRCDYEPDCKDVSDEIG-----CPVMRNCT 2509
Query: 3307 ENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQK--------PVCAAKKFQCD 3462
E + C NT C C D P C KF C
Sbjct: 2510 EGFVNCANTTGCYMPTWRCDGEND-----------CWDNSDEQDCPTAIPTCPEDKFLCA 2558
Query: 3463 NHRCIPEQWKXXXXXXXXXXXXEKL---EMCGNATCAANQFSCAN-GRCIPIYWLCDGDN 3630
N RCIP+ W+ L E+ C NQF C N CI W CDG
Sbjct: 2559 NGRCIPQSWRCDDEDDCTDATGGGLSSDELACVKHCKPNQFKCTNTSECISNSWQCDGHP 2618
Query: 3631 DCYDGTDEDKERCPPVQCSALQFRCANGRQCVPLR--NHXXXXXXXXXXXXXXXXAVTAE 3804
DC DG+DE + C C +F+C +C+P + +
Sbjct: 2619 DCADGSDEG-DHCSRRDCPETEFQCPTTNRCIPQKWVCDGEVDCGATQDDEMGCDEMMVN 2677
Query: 3805 SCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQ---------------C 3939
C F C +G CI SDEP + C G
Sbjct: 2678 ECDKTSFTC-KNGECISLLHVCDGEQDCVDGSDEPLY-CKEGDDGYDEEEGAGVDDHLCV 2735
Query: 3940 SSDQFKCGNGRCILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETC 4119
D F+C NGRCI N C+ +DC DGSDE R C+ + P + CE+ C
Sbjct: 2736 EPDHFRCNNGRCIERNLTCNVNDDCADGSDEDI-RLCRNTTLICAGP-DLFRCESG--AC 2791
Query: 4120 IPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCSFKCHNSPNGPICSCPFGEQL-VN- 4293
I + LCDG C +DE C + C C+ +C + P G C C G ++ VN
Sbjct: 2792 ITSNMLCDGANDCGDWSDEKS-CQVNECEMIPDLCAHECEDRPVGYECVCRKGFRVNVND 2850
Query: 4294 KTKCEPENECLDSSS--CSQRCKDEKHGFTCSCDEGYELDVDKRTCKVAD-NVKDTRIYV 4464
K C +EC + C+Q C + + C+C +G+ L D TC+ ++ ++
Sbjct: 2851 KHLCVDVDECTEQQPRPCTQTCVNTHGSYHCTCLDGFVLR-DNDTCRAEGRHILPPKLIF 2909
Query: 4465 SNRNRIYYSDHKLDNWHTFGAI-VENAIALAWDSLTDRIYWSDIRE-----KKILSANRN 4626
SNR Y + L T A + NAI L +D + YWSD+ K++ +
Sbjct: 2910 SNR--YYLREVDLSGGMTILAHNLTNAITLDFDWKDECYYWSDVTRTVTTVKRMCESGEE 2967
Query: 4627 GTNATVFIADGLDITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPR 4806
V L EG+A+DWVGRNLYW D L+TIEV+ L D + R +L+++ + +PR
Sbjct: 2968 NRPVEVIHRTNLKNPEGLAVDWVGRNLYWCDKGLDTIEVSKL-DGRYRRVLINKELQKPR 3026
Query: 4807 GIAVDPRKGVMFWTDWGQNPCIERASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADS 4986
IA+DP + M+WTDWG P I RA MDG+++ I++K ++ WPN + + + T+++++ D+
Sbjct: 3027 AIALDPYRRYMYWTDWGDQPHIGRAGMDGSNQTILIKEQLGWPNALTISFETNQLFWGDA 3086
Query: 4987 KLDFIDFVNYDGSGRTQVLASSK----FVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPN 5154
+ D+I + DG +L+ ++ + H A+A++ED +Y+SD + ++ K+
Sbjct: 3087 REDYIAVSDLDGQNVRILLSRARQPTLNLHHVFAIAVWEDRIYWSDLDSKSIEYCHKF-R 3145
Query: 5155 GTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTNPCSHLCLLN-NKNTFTCKCPMGEK 5331
G +T + + + H Q + NPC T C LC+L+ + + C CP
Sbjct: 3146 GDGCGTLINTIHRPMDIRVFHYYRQLQPEVNPCDTAGCQTLCVLSPDPPGYRCLCPDNFI 3205
Query: 5332 LDASGKKC 5355
L A GK C
Sbjct: 3206 LTADGKSC 3213
Score = 335 bits (860), Expect = 1e-89
Identities = 230/665 (34%), Positives = 321/665 (47%), Gaps = 25/665 (3%)
Frame = +1
Query: 3535 LEMCGNATCAANQFSCANG-RCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCAN 3711
L C N+T F C N CI I + CDGD DC DG+DE E P C
Sbjct: 880 LASCNNST----HFLCRNKIDCIEIKYTCDGDRDCEDGSDE--ETTPDGPCDP------- 926
Query: 3712 GRQCVPLRNHXXXXXXXXXXXXXXXXAVTAESCTPDQFKCVSSGLCIPASWKXXXXXXXX 3891
C RN FKC CI S
Sbjct: 927 --NCDLERN----------------------------FKC-DEQRCISRSHVCDGSVDCI 955
Query: 3892 XXSDEPKFGCTSGRQCSSDQFKCG-NGRCILNNWLCDGENDCG--DGSDESS------ER 4044
SDE C + + CS F+C + RCI N W+CD DCG D SDE E
Sbjct: 956 DESDEDYINCPN-KTCSEHFFQCEVSHRCIPNTWVCDRHLDCGPNDSSDEPEHCHKCPEF 1014
Query: 4045 GCKTSMNARKCPFEHVACENDQ----ETCIPLHQLCDGKTHCPGGTDEGGRCARDLCSAD 4212
CK N+ PFE + D CI + QLC+G+T CP GTDEG RCA LC A
Sbjct: 1015 ECK---NSACVPFEFLCDGVDNCGVTNQCIKVTQLCNGRTDCPDGTDEGFRCAEKLCDAP 1071
Query: 4213 RAGCSFKCHNSPNGPICSCPFGEQLV-NKTKCEPENECLDSSSCSQRCKDEKHGFTCSCD 4389
CS CHN+P G ICSCP L N C ++ C + +CSQ C + C C
Sbjct: 1072 N-DCSHACHNAPEGLICSCPAHLFLQPNGRDCGHDHACDNWGTCSQICTKAGTHYRCGCV 1130
Query: 4390 EGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGAIVENAIAL--AWDS 4563
EGY L DK TC+ ++N + SNR I D +F + N IAL + +
Sbjct: 1131 EGYTLMYDKFTCR-SNNGDSPYVIFSNRQEILGVDLNTLGVRSFYTSLRNTIALDFLYRN 1189
Query: 4564 LTDRIYWSDIREKKILSAN-RNGT--NATVFIADGLDITEGIALDWVGRNLYWVDSSLNT 4734
+ +I+WSD+ + KI RN T N + GL EG+A+DW+G N+YW+DS+L+
Sbjct: 1190 ESVQIFWSDVMDDKIYRGTLRNDTLSNVEAVVQSGLSTAEGLAVDWIGMNIYWIDSNLDQ 1249
Query: 4735 IEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQ-NPCIERASMDGTDRQII 4911
IEVA +RTL+ V+ PR IA+DP +GV+FWTDW + +P +ER +M G +R +I
Sbjct: 1250 IEVAKTNGSFRRTLVAGDMVN-PRAIALDPMEGVLFWTDWEEGSPRLERCTMAGENRTVI 1308
Query: 4912 --VKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAI 5085
V + WPN IALDY RVY+ D++ D I + YDG V+ + HP ++ +
Sbjct: 1309 KYVGSDGGWPNGIALDYIPRRVYWIDARSDSIHTITYDGQDHHLVIKDQGVLAHPFSITV 1368
Query: 5086 FEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTN- 5262
F++ +Y++D R + K+ NGT T S+ G+ +H QP + NPC+ N
Sbjct: 1369 FDNYVYWTDWRTYSVIRANKW-NGTDVNVIQKTQSQPFGIQILHSSRQPNTQPNPCADNN 1427
Query: 5263 -PCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNVFGIEMNSASEKE 5439
CSHLCLL+ + C CP +L ++C+ + + L+ + T + G+++ +
Sbjct: 1428 GGCSHLCLLSVGSRHECACPHVMRLHEDRRQCVPN-EEILLFVVLTEIRGVDLQQPAHYT 1486
Query: 5440 TPVLA 5454
P ++
Sbjct: 1487 IPTIS 1491
Score = 333 bits (853), Expect = 1e-88
Identities = 270/980 (27%), Positives = 412/980 (41%), Gaps = 42/980 (4%)
Frame = +1
Query: 313 HSVSCIAEYQRCDNITDCADGSDEKDCPASTVD--CSSQNVFMCADGRQCFDVSKKCDGK 486
+ + CI CD DC DGSDE+ P D C + F C D ++C S CDG
Sbjct: 893 NKIDCIEIKYTCDGDRDCEDGSDEETTPDGPCDPNCDLERNFKC-DEQRCISRSHVCDGS 951
Query: 487 YDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCA--DGSDEPDTCEF 660
DC D SDE D + + C ++ F+C +CI +WVCD DC D SDEP+ C
Sbjct: 952 VDCIDESDE-DYINCPNKTCSEHFFQCEVSHRCIPNTWVCDRHLDCGPNDSSDEPEHCH- 1009
Query: 661 KKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLK 840
KC EF+CKN C P +F CD D+CG T CI +
Sbjct: 1010 -KCP--EFECKNSACVPFEFLCDGVDNCGV---------------------TNQCIKVTQ 1045
Query: 841 LCDGSKDCADGADEQ-QCSQNLCPSLG-CQAGCHPSPHGGECTCPSGYKLDDRFHRTCSD 1014
LC+G DC DG DE +C++ LC + C CH +P G C+CP+ L R C
Sbjct: 1046 LCNGRTDCPDGTDEGFRCAEKLCDAPNDCSHACHNAPEGLICSCPAHLFLQPN-GRDCGH 1104
Query: 1015 INECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLF 1194
+ C +G C Q+C + C C+ + +TL D T C SNN D +
Sbjct: 1105 DHACDNWGTCSQICTKAGTHYRCGCV-EGYTLMY------DKFT----CRSNNGDSPYVI 1153
Query: 1195 VARRE-----GLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADV 1359
+ R+ L L ++ ++ + +F+Y + +IFW+D + + +
Sbjct: 1154 FSNRQEILGVDLNTLGVRSFYTSLRNTIALDFLYRNE----SVQIFWSDVMDDKIYRGTL 1209
Query: 1360 DDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGL 1539
++ +S ++ + L LAVDWI +Y I+S +I+V+ +G R L+A +
Sbjct: 1210 RND-TLSNVEAVVQSGLSTAEGLAVDWIGMNIYWIDSNLDQIEVAKTNGSFRRTLVAGDM 1268
Query: 1540 TLPLDIALDPLRGEMFFTN----QLKLEAAAMDGTNRRTL--VNTHTHQVSGIVVDITAK 1701
P IALDP+ G +F+T+ +LE M G NR + V + +GI +D +
Sbjct: 1269 VNPRAIALDPMEGVLFWTDWEEGSPRLERCTMAGENRTVIKYVGSDGGWPNGIALDYIPR 1328
Query: 1702 RVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEK 1881
RVYW+D + D + +I Y G D +V + V+ HPF + +FD Y+YWTDW VI+ K
Sbjct: 1329 RVYWIDARSDSIHTITYDGQDHHLVIKDQGVLAHPFSITVFDNYVYWTDWRTYSVIRANK 1388
Query: 1882 FGSDTKLLWSNTENNVF------PMGISAYHPMAQPGPGQSECLAMKIENPC--TNADCE 2037
W+ T+ NV P GI H QP NPC N C
Sbjct: 1389 --------WNGTDVNVIQKTQSQPFGIQILHSSRQPNTQ---------PNPCADNNGGCS 1431
Query: 2038 GMCILSKDNGGFGVGYKCACPIGQKLVNGKR-CIDSIDYLLFSSNKIVRGIFPEINEKAL 2214
+C+LS G ++CACP +L +R C+ + + LLF +RG ++ +
Sbjct: 1432 HLCLLS-----VGSRHECACPHVMRLHEDRRQCVPNEEILLFVVLTEIRG----VDLQQP 1482
Query: 2215 AEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAP---VLVTH 2385
A +P + Q ++ ++ D+ ++ DI N I+ G P +L T
Sbjct: 1483 AHYTIP-TISHQTQVVQPAVLDYDISAARLYWNDIQLN---EIKSSGLATGPIETILDTD 1538
Query: 2386 NDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVH 2565
+ DWISK LY+ ++ G + +TE+ D +SVV
Sbjct: 1539 ISNSLGFAVDWISKLLYFSTGNETHSRIMVSNLNG----------EFVTEIADGLSVV-- 1586
Query: 2566 PWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTI 2745
L+ Y + N+T +A+DF NRL + + I
Sbjct: 1587 --NSLVVYPTS--------------------NSTFHPIDSLALDFETNRLYYISSNAGEI 1624
Query: 2746 SCMDFDGKNVVKL---DIDNPIPVAITIMNEYIYYVHQRPYSIRRVHK----------KN 2886
+ D ++++ DN ITI + IYY I R +K N
Sbjct: 1625 NYYDIGSGKIIQVLAPHEDNHPISTITIYRDSIYYDDNHDGRIMRCNKNLCQNPVSVRNN 1684
Query: 2887 GGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNEL 3066
G +R + +S +C +N + C LC ++SH
Sbjct: 1685 TSGLNAIRMYHPGAQS--GTNSCQKRND---------KSAGTGCEHLCIPVSAQSH---- 1729
Query: 3067 EAKCACRQGFMINKENNHSC 3126
C C G+ + N C
Sbjct: 1730 --VCRCAIGYRSDPRNPWRC 1747
Score = 328 bits (841), Expect = 2e-87
Identities = 199/617 (32%), Positives = 294/617 (47%), Gaps = 29/617 (4%)
Frame = +1
Query: 9115 HSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKK 9294
HS C N T F C + K +CI + CDGD C G DE T
Sbjct: 878 HSLASCNNST----HFLCRN-------KIDCIEIKYTCDGDRDCEDGSDEETTPDGPCDP 926
Query: 9295 ECN-KGEFRCSNQHCIHSTWECDGDNDCLDGSDE-HANCTYSSCQPDFFQC-ANHKCVPN 9465
C+ + F+C Q CI + CDG DC+D SDE + NC +C FFQC +H+C+PN
Sbjct: 927 NCDLERNFKCDEQRCISRSHVCDGSVDCIDESDEDYINCPNKTCSEHFFQCEVSHRCIPN 986
Query: 9466 SWKCDGNDDC--EDGSDEKD-CPKNSASAQKASKCSNGQFQC-------TSGECIDDAKV 9615
+W CD + DC D SDE + C K K S C +F C + +CI ++
Sbjct: 987 TWVCDRHLDCGPNDSSDEPEHCHKCPEFECKNSACVPFEFLCDGVDNCGVTNQCIKVTQL 1046
Query: 9616 CDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCH 9795
C+ DC D +DE C C C C + G C C + + + C
Sbjct: 1047 CNGRTDCPDGTDEGFRCAEKLCDAPND--CSHACHNAPEGLICSCPAHLFLQ-PNGRDCG 1103
Query: 9796 NVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIR 9975
+ + C + CSQ C Y+CGCV+GY L D +C R+ P+ + +N+ I
Sbjct: 1104 HDHAC-DNWGTCSQICTKAGTHYRCGCVEGYTLMYDKFTC-RSNNGDSPYVIFSNRQEIL 1161
Query: 9976 KISIDGNKYELAAQGFDNVVSLDI------------DLTEKKAYLIDQGKLRLLRVDLDE 10119
+ ++ N ++LD D+ + K Y +G LR
Sbjct: 1162 GVDLNTLGVRSFYTSLRNTIALDFLYRNESVQIFWSDVMDDKIY---RGTLR-------- 1210
Query: 10120 MDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQ 10299
+ LS+ E V++ + EG+AVDW+G +Y ++ I V + +G F +TL+ +
Sbjct: 1211 -NDTLSNVEAVVQSGLSTAEGLAVDWIGMNIYWIDSNLDQIEVAKTNGSFRRTLVAGDMV 1269
Query: 10300 QPKAIVVHPGKGYLFFTEWSL-QPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYF 10476
P+AI + P +G LF+T+W P + R + G + K D GWPN IA+DY
Sbjct: 1270 NPRAIALDPMEGVLFWTDWEEGSPRLERCTMAGE---NRTVIKYVGSDGGWPNGIALDYI 1326
Query: 10477 SDRLFWGDAHLNEIGFMDFDGNGRRHIPAQR--TSHVSSMVVFDDYLYWADWNLREVLRC 10650
R++W DA + I + +DG + + +H S+ VFD+Y+YW DW V+R
Sbjct: 1327 PRRVYWIDARSDSIHTITYDGQDHHLVIKDQGVLAHPFSITVFDNYVYWTDWRTYSVIRA 1386
Query: 10651 DKWTGKNETILKKTVQLPNDLRIVHPMRQP-AYPNPCGDNNGGCSHLCLIGAGGNGYTCS 10827
+KW G + +++KT P ++I+H RQP PNPC DNNGGCSHLCL+ G + C+
Sbjct: 1387 NKWNGTDVNVIQKTQSQPFGIQILHSSRQPNTQPNPCADNNGGCSHLCLLSVGSR-HECA 1445
Query: 10828 CPDQFVLLSDQKTCEPN 10878
CP L D++ C PN
Sbjct: 1446 CPHVMRLHEDRRQCVPN 1462
Score = 288 bits (737), Expect = 3e-75
Identities = 282/1132 (24%), Positives = 467/1132 (40%), Gaps = 83/1132 (7%)
Frame = +1
Query: 544 CFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCK-NKRCQPRKF 720
C Q QF C +CI W CD S DC+DGSDE + C F C + RC P +
Sbjct: 3 CSQSQFTCVMDGKCIPALWRCDTSADCSDGSDEVGCDKAHACNEGMFHCTVSNRCIPHDW 62
Query: 721 RCDYYDDCG--------DNSDEDE--CGEY-RCPPGKWNCPGTGHCIDQLKLCDGSKDCA 867
CD DCG D SDED C + +C P + C G C++ + CDG+ DC+
Sbjct: 63 TCDGDVDCGLVEKYDMVDVSDEDPQLCRAHTKCLPTQALC-SDGKCLEIDRFCDGAWDCS 121
Query: 868 DGADEQQCSQN----------LCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDI 1017
+ DE CS N C +L C C + G C C + + C D
Sbjct: 122 N--DELNCSSNDTATASAPTSACDALKCSYDCRLTSEGARCFCAKDSQPNGS---VCEDF 176
Query: 1018 NECAEFGYCDQLCANHRPGFTCSCL-------GDCFTLQMEHGPGKDNLTMRGYCVSNNA 1176
+EC G CDQ+C N + CSC C + + KD T + N
Sbjct: 177 DECQIEGLCDQMCKNQPGAYQCSCTTGYVRQGNTCTAVNLP----KDEPTSLFFTTFNKV 232
Query: 1177 DKMKLFVARREGLYRLN-PKNPDEEVKKLAS-GEFIYGIDFDYGDRKIFWTDRLAHSA-- 1344
K+ ++ R + N P N E + L I ++ + +R F R+ +
Sbjct: 233 KKVS--ISNRTSVLAGNFPTNETVEEEYLKQPNPRIRAMEMVHRNRT-FCLARIDGKSLL 289
Query: 1345 --FSADVDDEGEISQIKKL--SLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGER 1512
+S D + L +L+ +V R +DW++ Y ++ I V S
Sbjct: 290 ECYSVDNTSHSWVMPRPDLFPNLEDIVDIR---LDWVSGNWYYLDQQREIIFVCSPQMVH 346
Query: 1513 RTVLLA--DGLTLPLDIALDPLRGEMFFTN----QLKLEAAAMDGTNRRTLVNTHTHQVS 1674
+++ + P +ALDP +G +FF+ + +E + +DGTNR ++V
Sbjct: 347 CAIIVEALSEVLRPRRMALDPTKGFLFFSKWGSGDVSIERSLLDGTNRTSIVLNKIITPL 406
Query: 1675 GIVVDITAKRVYWVDPKVDRLESIDYQGNDR---RIVAQGMNVVPHPFGLALFDQYLYWT 1845
I +D+ + VYWVD +D ++ ++Y G+ R + Q + + L +F++ +Y
Sbjct: 407 DIALDLVMQHVYWVDTHLDTVQRVNYDGSGRWFPKRSTQFLFNFQMLYALDVFERTIYLA 466
Query: 1846 DWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPC-- 2019
W ++ + + +++ N + V + +H QP ++ +PC
Sbjct: 467 SWQNGSIVALNGTTGEARVIVPNAPHAVH---LHVFHRQKQP----------EVAHPCRI 513
Query: 2020 TNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGKRC--IDSIDYLLF--SSNKIVRGI 2187
N C+ +CI G + +C C G +L +C I +LL+ S+ ++RG
Sbjct: 514 QNGGCDQLCIPVWKKIGVAIA-QCMCSPGYRLKTKSQCVLIKRPTFLLYAKSNPAMIRGF 572
Query: 2188 FPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDG-EGA 2364
I + EA++PI+ + I + VE + FF ++D +RI +G
Sbjct: 573 AVGIKSQ---EAIVPITDLGP-HITFDYHVEDQL---IFFSHGVIDKPSFRIEAQKLDGT 625
Query: 2365 APVLVTHNDG-LFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELR 2541
L+ + G +S+DW+ +++ D+ RN + V+K+G + +R ++ +L
Sbjct: 626 QRELLLESPGSCDGISYDWLGNNIFWTDSDRNHISVIKLG-------PKRMRYTVLRQLY 678
Query: 2542 DPVSVVVHPWKGLLFYAEAMRPAA-IYRCHIDGQNCQVI---RNTTLGRPSEMAIDFAEN 2709
P S+VV P +G ++++ P+ I R ++G +++ + + P+ ++ID +
Sbjct: 679 APKSIVVDPKQGWMYWSSWSVPSGRIDRAWMNGTQPELLVSSKERPIEWPTGLSIDMIQK 738
Query: 2710 RLCWGDTLLKTISCMDFDGKNVVKL---DIDNPIPVAITIMNEYIYYVHQRPYSIRRVHK 2880
RL W D L I ++ DG N V L N PVA+ + + +Y+ + K
Sbjct: 739 RLYWCDARLSFIESINLDGSNRVLLFDGRSQNQFPVALAVHRQLLYFADNVK---GHIEK 795
Query: 2881 KNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPN 3060
N ++ ++ + LK + Q + + C C +C TP
Sbjct: 796 LNLSDPHLLETITIEKPQVLGLKIFDNLTQ--YGGNGRNACEI-DCPGICLNTP------ 846
Query: 3061 ELEAKCACRQGFMIN-KENNHSCQKDPAEKIEQLCS-SNSTQFQCKNG-RCIPKEWKCDG 3231
A C C G +++ P + L S +NST F C+N CI ++ CDG
Sbjct: 847 VAVASCKCEDGQVLSLSSEGKPVACVPFDLQHSLASCNNSTHFLCRNKIDCIEIKYTCDG 906
Query: 3232 ENDCLDESDEIDEKGDKCFHETEC-AENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVK 3408
+ DC D SDE C + C E KC + ++CI
Sbjct: 907 DRDCEDGSDEETTPDGPC--DPNCDLERNFKC-DEQRCISRSHVCDGSVDCIDESDEDYI 963
Query: 3409 YCKDGQKPVCAAKKFQCD-NHRCIPEQW----------KXXXXXXXXXXXXEKLEMCGNA 3555
C + C+ FQC+ +HRCIP W + E C N+
Sbjct: 964 NCPN---KTCSEHFFQCEVSHRCIPNTWVCDRHLDCGPNDSSDEPEHCHKCPEFE-CKNS 1019
Query: 3556 TCAANQFSC-------ANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSA 3690
C +F C +CI + LC+G DC DGTDE RC C A
Sbjct: 1020 ACVPFEFLCDGVDNCGVTNQCIKVTQLCNGRTDCPDGTDEG-FRCAEKLCDA 1070
Score = 287 bits (734), Expect = 6e-75
Identities = 300/1192 (25%), Positives = 461/1192 (38%), Gaps = 163/1192 (13%)
Frame = +1
Query: 2275 VECDVHGNSFFYADIMDN--TIYRIRPDGEGAAPVLVTHNDGLFS---MSFDWISKQLYY 2439
++ D ++++D+ T+ R+ GE PV V H L + ++ DW+ + LY+
Sbjct: 2937 LDFDWKDECYYWSDVTRTVTTVKRMCESGEENRPVEVIHRTNLKNPEGLAVDWVGRNLYW 2996
Query: 2440 VDNIRNSLEVVKIGETGLVHPDELVRRQLIT-ELRDPVSVVVHPWKGLLFYAEAMRPAAI 2616
D +++EV K+ D RR LI EL+ P ++ + P++ +++ + I
Sbjct: 2997 CDKGLDTIEVSKL--------DGRYRRVLINKELQKPRAIALDPYRRYMYWTDWGDQPHI 3048
Query: 2617 YRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVKLDIDN 2796
R +DG N ++ LG P+ + I F N+L WGD I+ D DG+NV L
Sbjct: 3049 GRAGMDGSNQTILIKEQLGWPNALTISFETNQLFWGDAREDYIAVSDLDGQNVRILLSRA 3108
Query: 2797 PIPV-------AITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKAC 2955
P AI + + IY+ SI HK G G + R + ++
Sbjct: 3109 RQPTLNLHHVFAIAVWEDRIYWSDLDSKSIEYCHKFRGDGCGTL--INTIHRPM-DIRVF 3165
Query: 2956 SHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINKENNHSCQKD 3135
+ Q P+ +PC + C LC +P +C C F++ + SC +
Sbjct: 3166 HYYRQLQPE---VNPCDTAGCQTLCVLSPDPP-----GYRCLCPDNFILTADGK-SCAAN 3216
Query: 3136 PAEKIEQLCSSNSTQFQCKNG-RCIPKEWKCDGENDCLDESDE-------IDEKGD---- 3279
CS + FQC+ +CIP W+CD ++DC D SDE E G
Sbjct: 3217 --------CS--AAHFQCRTTFKCIPFYWRCDKQDDCGDGSDEPPNCPTFTCEAGQFQCL 3266
Query: 3280 --KCFHETECAENTIKC---RNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPV--- 3435
+C + ++ + +C + + C + +C +G +
Sbjct: 3267 NKRCINPSQICDGVDQCGDLSDERDCDRFECFSSHFKCGPSAAKNTSGFCIEGARRCDEE 3326
Query: 3436 ----------------CAAKKFQCDN-HRCIPEQWKXXXXXXXXXXXXEKLEMCGNA-TC 3561
C A +F+C N RCI W E ++CG A TC
Sbjct: 3327 VNCPNGEDEQNCEPKNCTATQFRCANGGRCIDRTWVCDNVPDCHDGSDE--QVCGPATTC 3384
Query: 3562 AANQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERCPP--VQCSALQFRCANGRQCVP-- 3729
++F C+ GRCIP WLCD + DC +G DE + P + C FRC N +C+P
Sbjct: 3385 PEHEFRCSEGRCIPQSWLCDDEKDCANGEDETENCQKPEAITCEPTSFRC-NNSKCIPGR 3443
Query: 3730 -------------------LRN-----------HXXXXXXXXXXXXXXXXAVTAESC--- 3810
LRN H E+C
Sbjct: 3444 WRCDFENDCGDNSDELNCELRNCSESEFRCRDGHCIRGIRRCDNEFNCADHSDEENCNVT 3503
Query: 3811 -TPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKCGNGRCILNN 3987
+ +QFKC S CI +K SDE C G +++C NG+CIL++
Sbjct: 3504 CSAEQFKCKSHPACISNKFKCDGDNDCIDESDEEDCECQEG------EYRCNNGKCILSS 3557
Query: 3988 WLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDGKTHCPGG 4167
W+CDG +DC D SDE E CK C C N CI +CD K C
Sbjct: 3558 WVCDGIDDCLDNSDEMGEY-CK----EHGCNKRAFRCAN--RNCIRKSLMCDNKDDCGDN 3610
Query: 4168 TDEGGRCARDLCSADRAGCSFKCHNSPNGPICSCPFGEQLVNKTKCEPENECLDSS---- 4335
+DE S CH P + + +C+ CLD S
Sbjct: 3611 SDEK---------------SALCHKCPPNSFRCNSDSKCIDIALRCDQTPHCLDESDEIG 3655
Query: 4336 ---------SCSQRCKDEKHGFTCSCDEGYELDVDKR--TCKVADNVKDTRIYVSNRNRI 4482
+CSQ C ++K +TC C EGY R TC D + + R
Sbjct: 3656 CIKTGCGFGACSQLCIEKKGHYTCRCAEGYVKGGPGRNATCVAVDEQGILLVASESDFRS 3715
Query: 4483 YYSDH-----------KLDNWHTFGAIVENAIALAW----DSLTDRIYWS---------- 4587
Y+D K+D + AI + I L W D+ ++I
Sbjct: 3716 LYADTPVMGYLQTSSLKIDRFDF--AITRHNITLFWIDSYDTSINKILMDTTVKDGGDYS 3773
Query: 4588 ---DIREKKIL-----------SANR----NGTNATVFIADGLDITEGIALDWVGRNLYW 4713
+ ++KI+ S +R +G +++V + D IA DW+ LY
Sbjct: 3774 RSPPVDKRKIVRRGLGPAPAPPSYDRIKTLDGKHSSVVLKDDEIHPIAIACDWLTERLYV 3833
Query: 4714 VDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQNPCIERASMDG 4893
++ + I V + TL P + VDP G+M W+ I + MDG
Sbjct: 3834 INKKRSNIFVMSFNGTNHTTLTA--TGKHPIDLVVDPVSGMMVWSIM---ETIISSGMDG 3888
Query: 4894 TDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPH 5073
+Q +V T + W + +A+D TT R+Y+AD + I+ G V+A P
Sbjct: 3889 RGKQKLVHTNVEWASGLAIDTTTKRLYWADYRKSTIETCLLLTGGDRHVIAELHDYSKPK 3948
Query: 5074 ALAIFEDMMY--YSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALG-----VVAVHPVLQP 5232
L +FED +Y ++ + KL Y + NGT + G V +HP+
Sbjct: 3949 LLDVFEDSVYVILYNQNILKLNKYGR-DNGTYMNEEARGAGGLAGYRSSDVHFIHPLKHD 4007
Query: 5233 VIKNNPCSTNPC--SHLCLLNNKNTF--TCKCPMGEK---LDASG--KKCID 5361
NPC +PC S +CLL+ + C CP D G K+C+D
Sbjct: 4008 RSVPNPCIISPCHNSTVCLLSTVSRLKRACVCPDARPRIVFDERGEVKECLD 4059
Score = 276 bits (707), Expect = 8e-72
Identities = 212/705 (30%), Positives = 302/705 (42%), Gaps = 41/705 (5%)
Frame = +1
Query: 142 TASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHP-----GCKSDQWQCDTY 306
TA C E+ F C +G+CI W CK +Q++C
Sbjct: 2545 TAIPTCPEDKFLCANGRCIPQSWRCDDEDDCTDATGGGLSSDELACVKHCKPNQFKCT-- 2602
Query: 307 TWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGK 486
++ CI+ +CD DCADGSDE D S DC + F C +C CDG+
Sbjct: 2603 --NTSECISNSWQCDGHPDCADGSDEGD-HCSRRDCP-ETEFQCPTTNRCIPQKWVCDGE 2658
Query: 487 YDCRDLSDEKDSCSRNHT-ACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFK 663
DC D++ C C + F C + +CI VCDG +DC DGSDEP C+
Sbjct: 2659 VDCGATQDDEMGCDEMMVNECDKTSFTCKNG-ECISLLHVCDGEQDCVDGSDEPLYCKEG 2717
Query: 664 KCTANE----------------FQCKNKRCQPRKFRCDYYDDCGDNSDEDE--CGEYR-- 783
+E F+C N RC R C+ DDC D SDED C
Sbjct: 2718 DDGYDEEEGAGVDDHLCVEPDHFRCNNGRCIERNLTCNVNDDCADGSDEDIRLCRNTTLI 2777
Query: 784 -CPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLG--CQAGCHPSPHGG 954
P + C +G CI LCDG+ DC D +DE+ C N C + C C P G
Sbjct: 2778 CAGPDLFRCE-SGACITSNMLCDGANDCGDWSDEKSCQVNECEMIPDLCAHECEDRPVGY 2836
Query: 955 ECTCPSGYKLDDRFHRTCSDINECAEFGY--CDQLCANHRPGFTCSCLGDCFTLQMEHGP 1128
EC C G++++ C D++EC E C Q C N + C+CL D F L
Sbjct: 2837 ECVCRKGFRVNVNDKHLCVDVDECTEQQPRPCTQTCVNTHGSYHCTCL-DGFVL------ 2889
Query: 1129 GKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKLASG-EFIYGIDFDYGD 1305
+DN T R + KL + R Y L + + LA +DFD+ D
Sbjct: 2890 -RDNDTCRAE--GRHILPPKLIFSNR---YYLREVDLSGGMTILAHNLTNAITLDFDWKD 2943
Query: 1306 RKIFWTDRLAHSAFSADVDDEGEISQ-IKKLSLKSLVYPRCLAVDWITNTLYIIESGSRR 1482
+W+D + + GE ++ ++ + +L P LAVDW+ LY + G
Sbjct: 2944 ECYYWSDVTRTVTTVKRMCESGEENRPVEVIHRTNLKNPEGLAVDWVGRNLYWCDKGLDT 3003
Query: 1483 IDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVN 1653
I+VS DG R VL+ L P IALDP R M++T +Q + A MDG+N+ L+
Sbjct: 3004 IEVSKLDGRYRRVLINKELQKPRAIALDPYRRYMYWTDWGDQPHIGRAGMDGSNQTILIK 3063
Query: 1654 THTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIV----AQGMNVVPHPFGLAL 1821
+ + + +++W D + D + D G + RI+ Q + H F +A+
Sbjct: 3064 EQLGWPNALTISFETNQLFWGDAREDYIAVSDLDGQNVRILLSRARQPTLNLHHVFAIAV 3123
Query: 1822 FDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAM 2001
++ +YW+D + KF D NT + PM I +H Q P
Sbjct: 3124 WEDRIYWSDLDSKSIEYCHKFRGDGCGTLINTIHR--PMDIRVFHYYRQLQPE------- 3174
Query: 2002 KIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKL-VNGKRC 2133
NPC A C+ +C+LS D GY+C CP L +GK C
Sbjct: 3175 --VNPCDTAGCQTLCVLSPD----PPGYRCLCPDNFILTADGKSC 3213
Score = 240 bits (612), Expect = 8e-61
Identities = 186/698 (26%), Positives = 286/698 (40%), Gaps = 50/698 (7%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAE 336
C FRCN+ KCI W C +++C CI
Sbjct: 3427 CEPTSFRCNNSKCIPGRWRCDFENDCGDNSDELNCELRNCSESEFRC-----RDGHCIRG 3481
Query: 337 YQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEK 516
+RCDN +CAD SDE++C V CS++ F C C KCDG DC D SDE+
Sbjct: 3482 IRRCDNEFNCADHSDEENC---NVTCSAEQ-FKCKSHPACISNKFKCDGDNDCIDESDEE 3537
Query: 517 DSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEP-DTCEFKKCTANEFQCK 693
D C + ++RC + +CI SWVCDG DC D SDE + C+ C F+C
Sbjct: 3538 DC------ECQEGEYRC-NNGKCILSSWVCDGIDDCLDNSDEMGEYCKEHGCNKRAFRCA 3590
Query: 694 NKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADG 873
N+ C + CD DDCGDNSDE ++CPP + C CID CD + C D
Sbjct: 3591 NRNCIRKSLMCDNKDDCGDNSDEKSALCHKCPPNSFRCNSDSKCIDIALRCDQTPHCLDE 3650
Query: 874 ADEQQCSQNLCPSLGC-QAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQ 1050
+DE +GC + GC FG C Q
Sbjct: 3651 SDE----------IGCIKTGCG--------------------------------FGACSQ 3668
Query: 1051 LCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARRE--GLYRL 1224
LC + +TC C ++ GPG++ CV+ + + L + + LY
Sbjct: 3669 LCIEKKGHYTCRCAEG----YVKGGPGRN-----ATCVAVDEQGILLVASESDFRSLYAD 3719
Query: 1225 NPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHS----AFSADVDDEGEISQIKK 1392
P + L F + I + +FW D S V D G+ S+
Sbjct: 3720 TPVMGYLQTSSLKIDRFDFAI--TRHNITLFWIDSYDTSINKILMDTTVKDGGDYSRSPP 3777
Query: 1393 LSLKSLV---------------------------------YPRCLAVDWITNTLYIIESG 1473
+ + +V +P +A DW+T LY+I
Sbjct: 3778 VDKRKIVRRGLGPAPAPPSYDRIKTLDGKHSSVVLKDDEIHPIAIACDWLTERLYVINKK 3837
Query: 1474 SRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTNQLKLEAAAMDGTNRRTLVN 1653
I V S++G T L A G P+D+ +DP+ G M ++ + ++ MDG ++ LV+
Sbjct: 3838 RSNIFVMSFNGTNHTTLTATG-KHPIDLVVDPVSGMMVWSIMETIISSGMDGRGKQKLVH 3896
Query: 1654 THTHQVSGIVVDITAKRVYWVDPKVDRLES-IDYQGNDRRIVAQGMNVVPHPFGLALFDQ 1830
T+ SG+ +D T KR+YW D + +E+ + G DR ++A+ ++ P L +F+
Sbjct: 3897 TNVEWASGLAIDTTTKRLYWADYRKSTIETCLLLTGGDRHVIAE-LHDYSKPKLLDVFED 3955
Query: 1831 YLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAY--------HPMAQPGPGQS 1986
+Y + + ++++ K+G D + G++ Y HP+ +
Sbjct: 3956 SVYVILYNQ-NILKLNKYGRDNGTYMNEEARGA--GGLAGYRSSDVHFIHPLKHDRSVPN 4012
Query: 1987 ECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACP 2100
C I +PC N+ +C+LS + + C CP
Sbjct: 4013 PC----IISPCHNST---VCLLSTVS---RLKRACVCP 4040
Score = 232 bits (592), Expect = 2e-58
Identities = 234/911 (25%), Positives = 373/911 (40%), Gaps = 67/911 (7%)
Frame = +1
Query: 3805 SCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKCG-NGRCIL 3981
+C+ QF CV G CIPA W+ SDE GC C+ F C + RCI
Sbjct: 2 TCSQSQFTCVMDGKCIPALWRCDTSADCSDGSDE--VGCDKAHACNEGMFHCTVSNRCIP 59
Query: 3982 NNWLCDGENDCG--------DGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQL 4137
++W CDG+ DCG D SDE + C+ KC C + + C+ + +
Sbjct: 60 HDWTCDGDVDCGLVEKYDMVDVSDEDPQL-CRAHT---KCLPTQALCSDGK--CLEIDRF 113
Query: 4138 CDGKTHCPGGTDEGGRCARDLCSA-------DRAGCSFKCHNSPNGPICSCPFGEQLVNK 4296
CDG C DE + D +A D CS+ C + G C C Q N
Sbjct: 114 CDGAWDC--SNDELNCSSNDTATASAPTSACDALKCSYDCRLTSEGARCFCAKDSQ-PNG 170
Query: 4297 TKCEPENECLDSSSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDT-------- 4452
+ CE +EC C Q CK++ + CSC GY + TC + KD
Sbjct: 171 SVCEDFDECQIEGLCDQMCKNQPGAYQCSCTTGYVRQGN--TCTAVNLPKDEPTSLFFTT 228
Query: 4453 -----RIYVSNRNRIYYSDHKLDNWHTFGAIVENAI--------ALAWDSLTDRIYWSDI 4593
++ +SNR + N+ T + E + A+ + I
Sbjct: 229 FNKVKKVSISNRTSVLAG-----NFPTNETVEEEYLKQPNPRIRAMEMVHRNRTFCLARI 283
Query: 4594 REKKILSANR--NGTNATVF----IADGLDITEGIALDWVGRNLYWVDSSLNTIEVANLE 4755
K +L N +++ V + L+ I LDWV N Y++D I V + +
Sbjct: 284 DGKSLLECYSVDNTSHSWVMPRPDLFPNLEDIVDIRLDWVSGNWYYLDQQREIIFVCSPQ 343
Query: 4756 DPKQRTLL-VHQNVSQPRGIAVDPRKGVMFWTDWGQNPC-IERASMDGTDRQIIVKTKIY 4929
++ V +PR +A+DP KG +F++ WG IER+ +DGT+R IV KI
Sbjct: 344 MVHCAIIVEALSEVLRPRRMALDPTKGFLFFSKWGSGDVSIERSLLDGTNRTSIVLNKII 403
Query: 4930 WPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFV---QHPHALAIFEDMM 5100
P IALD VY+ D+ LD + VNYDGSGR S++F+ Q +AL +FE +
Sbjct: 404 TPLDIALDLVMQHVYWVDTHLDTVQRVNYDGSGRWFPKRSTQFLFNFQMLYALDVFERTI 463
Query: 5101 YYSDRRLQKLQVYPKYPNGTTSE----YPSHTFSKALGVVAVHPVLQPVIKNNPC--STN 5262
Y + + + NGTT E P+ + L V H QP + +PC
Sbjct: 464 YLASWQNGSIVAL----NGTTGEARVIVPNAPHAVHLHV--FHRQKQPEVA-HPCRIQNG 516
Query: 5263 PCSHLCLLNNKN----TFTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTN---VFGIEMN 5421
C LC+ K C C G +L +C+ +P ++ K+N + G +
Sbjct: 517 GCDQLCIPVWKKIGVAIAQCMCSPGYRLKTK-SQCVLIKRPTFLLYAKSNPAMIRGFAVG 575
Query: 5422 SASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTV 5601
S++ +VP++ LG Y + +++ H K +I +
Sbjct: 576 IKSQE------AIVPITDLGPHITFDYH-VEDQLIFFSHGVIDKPSFRIEAQK------L 622
Query: 5602 NGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVILSNDQSX 5781
+G + + S P + +DW G N+ + I +I+ K+ R +L
Sbjct: 623 DGTQRELLLES--PGSCDGISYDWLGNNIFWTDSDRNHISVIKLGPKRMRYTVLRQ---- 676
Query: 5782 XXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELD---HIA 5952
+G+++W ++ RA ++G+ P ++ S+ ++ ++
Sbjct: 677 --LYAPKSIVVDPKQGWMYW--SSWSVPSGRIDRAWMNGTQPELLVSSKERPIEWPTGLS 732
Query: 5953 IDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQ---PNGLAFYGDRLFYADSAFD 6123
ID R+Y+ +A+ I S+ DG +R +L DG Q P LA + L++AD+
Sbjct: 733 IDMIQKRLYWCDARLSFIESINLDGSNR-VLLFDGRSQNQFPVALAVHRQLLYFADNVKG 791
Query: 6124 SIEVATINGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHINNGNCDHICIPLMFA 6303
IE ++ T K V L L + + C I +C IC+ A
Sbjct: 792 HIEKLNLSDPHLLETITIEKPQVLGLKIFDNLTQYGGNGRNACEI---DCPGICLNTPVA 848
Query: 6304 QRTCTCANGYV 6336
+C C +G V
Sbjct: 849 VASCKCEDGQV 859
Score = 213 bits (542), Expect = 1e-52
Identities = 246/1024 (24%), Positives = 408/1024 (39%), Gaps = 86/1024 (8%)
Frame = +1
Query: 6250 CHINNGNCDHICIPLMFAQRTCTCANGYVKDGQTSC----------KLFDESF-----VI 6384
C I G CD +C A + C+C GYV+ G T LF +F V
Sbjct: 179 CQIE-GLCDQMCKNQPGAYQ-CSCTTGYVRQGNTCTAVNLPKDEPTSLFFTTFNKVKKVS 236
Query: 6385 VATKTKVIG--YPIDETQSKGVAMEPIGGLSITGVDYDYESKTIYVAEASGINKGITAYT 6558
++ +T V+ +P +ET + +P I ++ + ++T +A G + + Y+
Sbjct: 237 ISNRTSVLAGNFPTNETVEEEYLKQP--NPRIRAMEMVHRNRTFCLARIDGKSL-LECYS 293
Query: 6559 IGESSPRAVIR--DSIGSLT-IKSLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILL 6729
+ +S V+ D +L I + +DW++ N Y++ D +R I V + I++
Sbjct: 294 VDNTSHSWVMPRPDLFPNLEDIVDIRLDWVSGNWYYL--DQQREIIFVCSPQMVHCAIIV 351
Query: 6730 TTKTET--PSSIAVDPVSRYLYWADQGQKP-TIQRSFLDGSRREVIVSSGIAEPTDLVVD 6900
+E P +A+DP +L+++ G +I+RS LDG+ R IV + I P D+ +D
Sbjct: 352 EALSEVLRPRRMALDPTKGFLFFSKWGSGDVSIERSLLDGTNRTSIVLNKIITPLDIALD 411
Query: 6901 VASKMIYWSDAKMDGIYRVRSTGGTPELVRSDIASAAGVALHGQNMYWTDNRLEKLFRAT 7080
+ + +YW D +D + RV G + L M + + E+
Sbjct: 412 LVMQHVYWVDTHLDTVQRVNYDGSGRWFPKRSTQ-----FLFNFQMLYALDVFERTIYLA 466
Query: 7081 SKPNQTSLLLSPTT-----VAASLKDIGDVAVFSSNNQPRASSPCQITDNLRKSPCTQLC 7245
S N + + L+ TT + + + VF QP + PC+I + C QLC
Sbjct: 467 SWQNGSIVALNGTTGEARVIVPNAPHAVHLHVFHRQKQPEVAHPCRI----QNGGCDQLC 522
Query: 7246 ---FATPGTQTPTCSCARGV-LKGRT---CEEPDTYIMFSDGDKIIDVAIEPDVKASR-- 7398
+ G C C+ G LK ++ + T+++++ + + +K+
Sbjct: 523 IPVWKKIGVAIAQCMCSPGYRLKTKSQCVLIKRPTFLLYAKSNPAMIRGFAVGIKSQEAI 582
Query: 7399 -PLKDPFPEISNLQTFDVDVNLRRVYF---VVESPVGVNISWFSMNNAENPRLVFGASKQ 7566
P+ D P I TFD V + ++F V++ P I ++ + L+
Sbjct: 583 VPITDLGPHI----TFDYHVEDQLIFFSHGVIDKP-SFRIEAQKLDGTQRELLLESPGS- 636
Query: 7567 PHAKEIRHISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHL--STIASGDWTYALAIDPC 7740
+ DWL I++T + I + + + + ++ +DP
Sbjct: 637 --------CDGISYDWLGNNIFWTDSDRNHISVIKLGPKRMRYTVLRQLYAPKSIVVDPK 688
Query: 7741 SGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSES---ISLPAAIAVDFRNQKIYW 7911
G ++WS S + RI+R+ + G +++VS I P +++D +++YW
Sbjct: 689 QGWMYWS------SWSVPSGRIDRAWMNGTQPELLVSSKERPIEWPTGLSIDMIQKRLYW 742
Query: 7912 ADVNRLNIEVADYDGQNRKVIASGYRAK----SLDIWDRWLYMSDPLSNGVFRIDKESGS 8079
D IE + DG NR ++ G +L + + LY +D + + +++
Sbjct: 743 CDARLSFIESINLDGSNRVLLFDGRSQNQFPVALAVHRQLLYFADNVKGHIEKLNLSDPH 802
Query: 8080 GLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLCTVVADDIGLA 8259
LE + ++ L++F + + + C+ D C +C +
Sbjct: 803 LLETITIEKPQVLGLKIFDNLTQYGGNGR-------NACEID---CPGIC------LNTP 846
Query: 8260 ASKVQCSCNDTYEL-VQEPGKDYPTQCVLRGSNSEPAKECLPPYNFQCGDG-SCILLGAT 8433
+ C C D L + GK P CV A C +F C + CI + T
Sbjct: 847 VAVASCKCEDGQVLSLSSEGK--PVACVPFDLQHSLA-SCNNSTHFLCRNKIDCIEIKYT 903
Query: 8434 CDSKPDCADASDE--NPNYCNTRSCPEDYNL-CTNRRCIDSAKKCNHIDDCGDGSDE--L 8598
CD DC D SDE P+ +C + N C +RCI + C+ DC D SDE +
Sbjct: 904 CDGDRDCEDGSDEETTPDGPCDPNCDLERNFKCDEQRCISRSHVCDGSVDCIDESDEDYI 963
Query: 8599 DCPSAVACAEGTFPCSNGH-CINQTKVCDGHNDCHDEQVSDE------------SLATCP 8739
+CP+ C+E F C H CI T VCD H DC SDE + C
Sbjct: 964 NCPNK-TCSEHFFQCEVSHRCIPNTWVCDRHLDCGPNDSSDEPEHCHKCPEFECKNSACV 1022
Query: 8740 GLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADE-----NQLFCMNQQCAQHYVRC 8904
C GV C TN CI+ LC+G DC D DE +L C+
Sbjct: 1023 PFEFLCDGVD-NCGVTNQCIKVTQLCNGRTDCPDGTDEGFRCAEKLCDAPNDCSHACHNA 1081
Query: 8905 PSGRCI---------PETWQCDGDNDCSDGWDETHTNCT--DTAGKKICVGDYLFQCDNL 9051
P G P C D+ C D W CT T + CV Y D
Sbjct: 1082 PEGLICSCPAHLFLQPNGRDCGHDHAC-DNWGTCSQICTKAGTHYRCGCVEGYTLMYDKF 1140
Query: 9052 KCIS 9063
C S
Sbjct: 1141 TCRS 1144
Score = 206 bits (525), Expect = 1e-50
Identities = 250/1073 (23%), Positives = 454/1073 (42%), Gaps = 56/1073 (5%)
Frame = +1
Query: 4264 SCPFGEQLVNKTKCEPE---NECLDSSS-CSQRCK---DEKHGFTCSCDEGYELDVDKRT 4422
S PFG Q+++ ++ +P N C D++ CS C +H C+C L D+R
Sbjct: 1402 SQPFGIQILHSSR-QPNTQPNPCADNNGGCSHLCLLSVGSRH--ECACPHVMRLHEDRRQ 1458
Query: 4423 CKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGAI-----VENAIALAWDSLTDRIYWS 4587
C + + + R D + +T I V L +D R+YW+
Sbjct: 1459 CVPNEEILLFVVLTEIRG----VDLQQPAHYTIPTISHQTQVVQPAVLDYDISAARLYWN 1514
Query: 4588 DIREKKILSAN-RNGTNATVFIADGLDITEGIALDWVGRNLYWV--DSSLNTIEVANLED 4758
DI+ +I S+ G T+ D + + G A+DW+ + LY+ + + + I V+NL
Sbjct: 1515 DIQLNEIKSSGLATGPIETILDTD-ISNSLGFAVDWISKLLYFSTGNETHSRIMVSNLNG 1573
Query: 4759 PKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQNPCIERASMDGTDRQIIVKTKIYWPN 4938
+ + +S + V P F +P +
Sbjct: 1574 --EFVTEIADGLSVVNSLVVYPTSNSTF------HPI----------------------D 1603
Query: 4939 TIALDYTTDRVYFADSKLDFIDFVNYD-GSGR-TQVLASSKFVQHPHALAIFEDMMYYSD 5112
++ALD+ T+R+Y+ S I++ YD GSG+ QVLA + + I+ D +YY D
Sbjct: 1604 SLALDFETNRLYYISSNAGEINY--YDIGSGKIIQVLAPHEDNHPISTITIYRDSIYYDD 1661
Query: 5113 RRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAV---HPVLQPVI-----KNNPCSTNPC 5268
++ N + P + G+ A+ HP Q +N+ + C
Sbjct: 1662 NHDGRIM----RCNKNLCQNPVSVRNNTSGLNAIRMYHPGAQSGTNSCQKRNDKSAGTGC 1717
Query: 5269 SHLCLLNNKNTFTCKCPMGEKLDASGK-KCI--DDAKPFLVIIQKTNVFGIEMNSASEKE 5439
HLC+ + + C+C +G + D +CI DD LV + GI ++S+ E
Sbjct: 1718 EHLCIPVSAQSHVCRCAIGYRSDPRNPWRCIGLDD---ILVYSVGHQLKGIALSSSDEST 1774
Query: 5440 TPV--LAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNGGN 5613
+ + PL + A +D + ++I + ++ +I D + ++ N
Sbjct: 1775 GSLRNRESLGPLQQISLATSIDFDVAHDYVYIAD--TDRGSITRIKRDGSAREVIIS--N 1830
Query: 5614 KTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVILSNDQSXXXXX 5793
++ + D + DW N+ ++ IE+ R G R V+ S+ +S
Sbjct: 1831 FEQVVDGSTLDWLGGIAIDWVAENIYWTDQKRNLIEVARLNG-TLRYVVASDVES----- 1884
Query: 5794 XXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAIDTTNTR 5973
+GY+F++ RG + R GLDGS ++ + A + +A+D N
Sbjct: 1885 -PQLLAIDPIQGYLFYVTRG------TIGRMGLDGSGNFILVNRSSA-ISDLALDLDNQV 1936
Query: 5974 VYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAFDSIEVATINGD 6153
VY+ E I V YDG + +L+ P L +GD +++ADS + E N
Sbjct: 1937 VYWCETSTDTIWKVDYDGNLKRLLLNGTSHNPKSLDLFGDSIYWADSRGNIYEAGLSNIF 1996
Query: 6154 SQPPQWTHFKKDVENLANIKALQPRASSSGHPCHINNGNCDHICIPLMFAQRTCTCANGY 6333
+ + +V +L +IK R S + C ++NG C +C+ C C++G
Sbjct: 1997 NY--RSVVEALEVSSLKDIKVFSSRKQSKTNACGVSNGGCQELCL-FNGTHPICACSHGK 2053
Query: 6334 VKDGQ-TSCKLFDESFVIVATKTKV----------IGYPIDETQSKGVAMEPIGGLSITG 6480
+ +C+ + E+F+I + ++ + I PI E ++ I
Sbjct: 2054 ISSADLKTCEPY-ENFLIFSRQSAIESIHMTDANNINGPIPEIKNSSYLKNTI------A 2106
Query: 6481 VDYDYESKTIYVAEA--SGINKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINYNMY 6654
+ YDYE + I+ ++ S IN + G + R V + LT++ LA + + ++
Sbjct: 2107 LSYDYEQQLIFYSDIDHSTIN---CVFFNGTNHRRIVTK----QLTVEGLAFNVLTRVLF 2159
Query: 6655 FI-NHDAERTNIEVSKLDGT--------YRKILLTTKTETPSSIAVDPVSRYLYWADQGQ 6807
+ N++A +++++K T + ++ T+ P IAV+P +YW + Q
Sbjct: 2160 WTSNNEAAIRSLDLNKASLTDPAANAELVQDVIKLRATDKPRGIAVEPCLAMVYWTNWNQ 2219
Query: 6808 -KPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTG-GTPE 6981
+IQR++ G E I++S I P L +D ++ +YW+DA +D + R G
Sbjct: 2220 HAASIQRAYPSGYGLESIITSDIQMPNALTLDYQARKLYWADALLDKVERTDYDGKHRVV 2279
Query: 6982 LVRSDIASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAV 7161
L S +A+ G ++WTD + + RA +K + + ++L +A + +G VAV
Sbjct: 2280 LAHSTPKHPFALAVFGDLLFWTDLTVHAVIRA-NKYSGSDIVLLRRDIA---QPMGIVAV 2335
Query: 7162 FSSNNQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCARGVL--KGRTC 7314
+ + A PCQ+ + C +C + C C +GVL G+ C
Sbjct: 2336 QQIDKECSA-DPCQVMNGF----CEDVCLIDAAGKV-ECHCTQGVLAADGQRC 2382
Score = 181 bits (460), Expect = 4e-43
Identities = 145/542 (26%), Positives = 237/542 (42%), Gaps = 43/542 (7%)
Frame = +1
Query: 9298 CNKGEFRC-SNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCA-NHKCVPNSW 9471
C++ +F C + CI + W CD DC DGSDE +C F C +++C+P+ W
Sbjct: 3 CSQSQFTCVMDGKCIPALWRCDTSADCSDGSDEVGCDKAHACNEGMFHCTVSNRCIPHDW 62
Query: 9472 KCDGNDDCE--DGSDEKDCPKNSASAQKA-SKCSNGQFQCTSGECIDDAKVCDRNFDCTD 9642
CDG+ DC + D D +A +KC Q C+ G+C++ + CD +DC
Sbjct: 63 TCDGDVDCGLVEKYDMVDVSDEDPQLCRAHTKCLPTQALCSDGKCLEIDRFCDGAWDC-- 120
Query: 9643 RSDESSLCFIDECSLAEKPL-------CEQKCMDMKIGYKCDCFEGFAIDISDQKS-CHN 9798
S++ C ++ + A P C C G +C C A D S C +
Sbjct: 121 -SNDELNCSSNDTATASAPTSACDALKCSYDCRLTSEGARCFC----AKDSQPNGSVCED 175
Query: 9799 VNECY-EGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEM-EPEP---FFLLANK 9963
+EC EG+ C Q C ++ G+Y+C C GY ++C + + EP FF NK
Sbjct: 176 FDECQIEGL--CDQMCKNQPGAYQCSCTTGY--VRQGNTCTAVNLPKDEPTSLFFTTFNK 231
Query: 9964 HYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLID----------------QGKLR 10095
++K+SI N+ + A F +++ + ++ I GK
Sbjct: 232 --VKKVSI-SNRTSVLAGNFPTNETVEEEYLKQPNPRIRAMEMVHRNRTFCLARIDGKSL 288
Query: 10096 LLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCK 10275
L +D L N+ I +DWV Y L++Q I VC C
Sbjct: 289 LECYSVDNTSHSWVMPRPDLFPNLEDIVDIRLDWVSGNWYYLDQQREIIFVCSPQMVHCA 348
Query: 10276 TLIR--DRIQQPKAIVVHPGKGYLFFTEW-SLQPYIGRIALDGSPELQDPIFKLAEHDLG 10446
++ + +P+ + + P KG+LFF++W S I R LDG+ + K+
Sbjct: 349 IIVEALSEVLRPRRMALDPTKGFLFFSKWGSGDVSIERSLLDGTNRTSIVLNKIIT---- 404
Query: 10447 WPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHIPAQRTSH------VSSMVVFDDY 10608
P IA+D ++W D HL+ + +++DG+G R P + T + ++ VF+
Sbjct: 405 -PLDIALDLVMQHVYWVDTHLDTVQRVNYDGSG-RWFPKRSTQFLFNFQMLYALDVFERT 462
Query: 10609 LYWADWNLREVLRCDKWTGKNETILKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHL 10788
+Y A W ++ + TG+ I+ + L + H +QP +PC NGGC L
Sbjct: 463 IYLASWQNGSIVALNGTTGEARVIVPNAPHAVH-LHVFHRQKQPEVAHPCRIQNGGCDQL 521
Query: 10789 CL 10794
C+
Sbjct: 522 CI 523
Score = 176 bits (445), Expect = 2e-41
Identities = 232/1076 (21%), Positives = 432/1076 (39%), Gaps = 49/1076 (4%)
Frame = +1
Query: 5149 PNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCST-NPCSHLCLLNNKNTFTCKCPMG 5325
P G P+H F + G H ++ C CS +C + + C C G
Sbjct: 1082 PEGLICSCPAHLFLQPNGRDCGH--------DHACDNWGTCSQICTKAGTH-YRCGCVEG 1132
Query: 5326 EKLDASGKKCIDDA--KPFLVIIQKTNVFGIEMNSASEKETPVLAGMVPLSGLGN--AFD 5493
L C + P+++ + + G+++N+ + + L N A D
Sbjct: 1133 YTLMYDKFTCRSNNGDSPYVIFSNRQEILGVDLNTLGVRSF--------YTSLRNTIALD 1184
Query: 5494 AAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNG---GNKTKMFSSAVPDDAYCLG 5664
Y S ++F + D IYR T+ N + S + A L
Sbjct: 1185 FLYRNESVQIFWSD-----------VMDDKIYRGTLRNDTLSNVEAVVQSGL-STAEGLA 1232
Query: 5665 FDWNGRNLVVGNKITQTIEIIRTQGKQYRSVILSNDQSXXXXXXXXXXXXXXXKGYVFWL 5844
DW G N+ + IE+ +T G +R +++ D +G +FW
Sbjct: 1233 VDWIGMNIYWIDSNLDQIEVAKTNGS-FRRTLVAGDM-----VNPRAIALDPMEGVLFWT 1286
Query: 5845 DRGGGAADAKVARAGLDGSNPLVI--ASNDLAELDHIAIDTTNTRVYFSEAKAGRISSVT 6018
D G+ ++ R + G N VI +D + IA+D RVY+ +A++ I ++T
Sbjct: 1287 DWEEGSP--RLERCTMAGENRTVIKYVGSDGGWPNGIALDYIPRRVYWIDARSDSIHTIT 1344
Query: 6019 YDGQDRHYVLSDGG--RQPNGLAFYGDRLFYAD-SAFDSIEVATINGDS----QPPQWTH 6177
YDGQD H V+ D G P + + + +++ D + I NG Q Q
Sbjct: 1345 YDGQDHHLVIKDQGVLAHPFSITVFDNYVYWTDWRTYSVIRANKWNGTDVNVIQKTQSQP 1404
Query: 6178 FKKDVENLANIKALQPRASSSGHPCHINNGNCDHICIPLMFAQRTCTCANGY-VKDGQTS 6354
F + + + QP +PC NNG C H+C+ + ++ C C + + + +
Sbjct: 1405 FGIQILHSSRQPNTQP------NPCADNNGGCSHLCLLSVGSRHECACPHVMRLHEDRRQ 1458
Query: 6355 CKLFDESFVIVATKTKVIG--------YPIDETQSKGVAMEPIGGLSITGVDYDYESKTI 6510
C + +E ++ T++ G Y I + ++P +DYD + +
Sbjct: 1459 C-VPNEEILLFVVLTEIRGVDLQQPAHYTIPTISHQTQVVQP------AVLDYDISAARL 1511
Query: 6511 Y-------VAEASGINKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINYNMYFINHD 6669
Y ++SG+ G P I D+ S ++ A+DWI+ +YF +
Sbjct: 1512 YWNDIQLNEIKSSGLATG----------PIETILDTDISNSL-GFAVDWISKLLYFSTGN 1560
Query: 6670 AERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQRSFLDGSRR 6849
+ I VS L+G + TE ++V V+ + + PT +F
Sbjct: 1561 ETHSRIMVSNLNGEF-------VTEIADGLSV--VNSLVVY------PTSNSTF------ 1599
Query: 6850 EVIVSSGIAEPTD-LVVDVASKMIYWSDAKMDGI-YRVRSTGGTPELV--RSDIASAAGV 7017
P D L +D + +Y+ + I Y +G +++ D + +
Sbjct: 1600 ---------HPIDSLALDFETNRLYYISSNAGEINYYDIGSGKIIQVLAPHEDNHPISTI 1650
Query: 7018 ALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRASSP 7197
++ ++Y+ DN ++ R +L +P +V + + + ++ Q +S
Sbjct: 1651 TIYRDSIYYDDNHDGRIMRCNK-----NLCQNPVSVRNNTSGLNAIRMYHPGAQSGTNSC 1705
Query: 7198 CQITDNLRKSPCTQLCFATPGTQTPTCSCARGVLKGR----TCEEPDTYIMFSDGDKIID 7365
+ D + C LC Q+ C CA G C D +++S G ++
Sbjct: 1706 QKRNDKSAGTGCEHLCIPV-SAQSHVCRCAIGYRSDPRNPWRCIGLDDILVYSVGHQLKG 1764
Query: 7366 VAIEPDVKASRPLKD-----PFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNA 7530
+A+ +++ L++ P +IS + D DV VY + ++ G +I+ + +
Sbjct: 1765 IALSSSDESTGSLRNRESLGPLQQISLATSIDFDVAHDYVY-IADTDRG-SITRIKRDGS 1822
Query: 7531 ENPRLVFGASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTIASG- 7707
++ + + + + +DW+ + IY+T + + G +AS
Sbjct: 1823 AREVIISNFEQVVDGSTLDWLGGIAIDWVAENIYWTDQKRNLIEVARLNGTLRYVVASDV 1882
Query: 7708 DWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVD 7887
+ LAIDP G LF+ G I R L G ++V+ S ++ + +A+D
Sbjct: 1883 ESPQLLAIDPIQGYLFYVTRG----------TIGRMGLDGSGNFILVNRSSAI-SDLALD 1931
Query: 7888 FRNQKIYWADVNRLNIEVADYDGQNRKVIASG--YRAKSLDIWDRWLYMSDPLSNGVFRI 8061
NQ +YW + + I DYDG ++++ +G + KSLD++ +Y +D N ++
Sbjct: 1932 LDNQVVYWCETSTDTIWKVDYDGNLKRLLLNGTSHNPKSLDLFGDSIYWADSRGN-IYE- 1989
Query: 8062 DKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLC 8229
+GL N+ + R + AL V +S D++ + + T+ C NGGC +LC
Sbjct: 1990 -----AGLSNIFNYRSVVEALEV-SSLKDIKVFSSRKQSKTN-ACGVSNGGCQELC 2038
Score = 171 bits (432), Expect = 6e-40
Identities = 161/689 (23%), Positives = 261/689 (37%), Gaps = 17/689 (2%)
Frame = +1
Query: 11494 TCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCS-ESEFRCNDGKC 11670
+C++ F C CI ++ CD + DC D SDE G C E F+C++ +C
Sbjct: 882 SCNNSTHFLCRNKIDCIEIKYTCDGDRDCEDGSDEETTPDGPCDPNCDLERNFKCDEQRC 941
Query: 11671 IPGSKVCDGTIQCSDGLDES--QCTLRRCLPGHRQCD-DGTCIAEHKWCDRKKDC-PN-A 11835
I S VCDG++ C D DE C + C QC+ CI CDR DC PN +
Sbjct: 942 ISRSHVCDGSVDCIDESDEDYINCPNKTCSEHFFQCEVSHRCIPNTWVCDRHLDCGPNDS 1001
Query: 11836 ADE-LHCEDVSRRTCSPFEFECANSVCIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPL 12012
+DE HC EFEC NS C+P +F+ CD
Sbjct: 1002 SDEPEHCHKCP-------EFECKNSACVPFEFL----------------------CDGV- 1031
Query: 12013 RFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSFSEYGDCSSDQFKCANGKCVNG 12192
C + C+ + QLCNG DC D + + F+CA
Sbjct: 1032 -DNCGVTNQCIKVTQLCNGRTDC-------------------PDGTDEGFRCAE------ 1065
Query: 12193 TVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKHICTDVRDGFYCHCRDGFRPDP 12372
CD +D C H C + +G C C P
Sbjct: 1066 -KLCDAPND---------------------------CSHACHNAPEGLICSCPAHLFLQP 1097
Query: 12373 QSPKECIDIDECAGNNTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRA-KGDAAN 12549
++C C TC+Q+C Y C C E Y ++ T CR+ GD+
Sbjct: 1098 NG-RDCGHDHACDNWGTCSQICTKAGTHYRCGCVEGY--TLMYDKFT---CRSNNGDSPY 1151
Query: 12550 VMIGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERTIYRSA 12729
V+ ++ + L+ G + ++W D + IYR
Sbjct: 1152 VIFSNRQEILGVDLNTLGVRSFYTSLRNTIALDFLYRNESVQ---IFWSDVMDDKIYRGT 1208
Query: 12730 IANGNQSHEGQKLDVDFAAMGVVPTA--IAVDYTTGNLFIAAVSENIENGLVTARKKRMS 12903
+ N S +V+ + TA +AVD+ N++ + N++
Sbjct: 1209 LRNDTLS------NVEAVVQSGLSTAEGLAVDWIGMNIY--WIDSNLDQ----------- 1249
Query: 12904 EPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSD-AGLHAKIECAD 13080
I V +G + + +VAG + P A+ P G + ++D ++E
Sbjct: 1250 ----------IEVAKTNGSFRRTLVAGDMVNPRAIALDPMEGVLFWTDWEEGSPRLERCT 1299
Query: 13081 MDGTHRQII--VKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRH 13254
M G +R +I V P +A+D R+YW+D + + + DG + V+ D+
Sbjct: 1300 MAGENRTVIKYVGSDGGWPNGIALDY-IPRRVYWIDARSDSIHTITYDGQDHHLVIKDQG 1358
Query: 13255 I---PYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAK-DT 13422
+ P+++ VF+N++YW + ++ +K+ V+V+ +++ + +T
Sbjct: 1359 VLAHPFSITVFDNYVYWTDWRTYSVIRANKWNGTDVNVIQKTQSQPFGIQILHSSRQPNT 1418
Query: 13423 QRTVSGCERAQCSHLCVSLPSTGFACLCP 13509
Q CSHLC+ + C CP
Sbjct: 1419 QPNPCADNNGGCSHLCLLSVGSRHECACP 1447
Score = 164 bits (414), Expect = 8e-38
Identities = 110/333 (33%), Positives = 150/333 (45%), Gaps = 13/333 (3%)
Frame = +1
Query: 151 SVCNENDFRCNDGKCI--RTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVS 324
S C+ ++F C +G CI H C ++C+ +
Sbjct: 2388 SNCSSSEFSCTNGNCIPFHLTCDGVKNCLDGSDELVTFCAHRPCPDGFFRCN-----NAR 2442
Query: 325 CIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDL 504
CI + Q+C++I +C DGSDE C C++ F C DG QC S +CD + DC+D+
Sbjct: 2443 CIPKNQQCNHIQNCGDGSDEVGC-----SCNNATHFRCTDG-QCIVKSMRCDYEPDCKDV 2496
Query: 505 SDEKD-SCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPD-TCEFKKCTAN 678
SDE RN T F CA+ T C +W CDG DC D SDE D C +
Sbjct: 2497 SDEIGCPVMRNCTEGF---VNCANTTGCYMPTWRCDGENDCWDNSDEQDCPTAIPTCPED 2553
Query: 679 EFQCKNKRCQPRKFRCDYYDDCGD------NSDEDECGEYRCPPGKWNCPGTGHCIDQLK 840
+F C N RC P+ +RCD DDC D +SDE C ++ C P ++ C T CI
Sbjct: 2554 KFLCANGRCIPQSWRCDDEDDCTDATGGGLSSDELACVKH-CKPNQFKCTNTSECISNSW 2612
Query: 841 LCDGSKDCADGADE-QQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDI 1017
CDG DCADG+DE CS+ CP Q P C P + D +
Sbjct: 2613 QCDGHPDCADGSDEGDHCSRRDCPETEFQC-----PTTNRC-IPQKWVCDGEVDCGATQD 2666
Query: 1018 NECAEFGYCDQLCANH--RPGFTCSCLGDCFTL 1110
+E CD++ N + FTC G+C +L
Sbjct: 2667 DEMG----CDEMMVNECDKTSFTCK-NGECISL 2694
Score = 162 bits (410), Expect = 2e-37
Identities = 108/327 (33%), Positives = 149/327 (45%), Gaps = 26/327 (7%)
Frame = +1
Query: 160 NENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCK--SDQWQCDTYT-------- 309
N FRC DG+CI P CK SD+ C
Sbjct: 2469 NATHFRCTDGQCIVKSMRCDY--------------EPDCKDVSDEIGCPVMRNCTEGFVN 2514
Query: 310 -WHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGK 486
++ C RCD DC D SDE+DCP + C ++ F+CA+GR C S +CD +
Sbjct: 2515 CANTTGCYMPTWRCDGENDCWDNSDEQDCPTAIPTCP-EDKFLCANGR-CIPQSWRCDDE 2572
Query: 487 YDCRD-----LSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDT 651
DC D LS ++ +C ++ C QF+C + ++CI SW CDG DCADGSDE D
Sbjct: 2573 DDCTDATGGGLSSDELACVKH---CKPNQFKCTNTSECISNSWQCDGHPDCADGSDEGDH 2629
Query: 652 CEFKKCTANEFQC-KNKRCQPRKFRCDYYDDCGDNSDE----DECGEYRCPPGKWNCPGT 816
C + C EFQC RC P+K+ CD DCG D+ DE C + C
Sbjct: 2630 CSRRDCPETEFQCPTTNRCIPQKWVCDGEVDCGATQDDEMGCDEMMVNECDKTSFTCK-N 2688
Query: 817 GHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDD-- 990
G CI L +CDG +DC DG+DE + + G H C P ++ ++
Sbjct: 2689 GECISLLHVCDGEQDCVDGSDEPLYCKEGDDGYDEEEGAGVDDH--LCVEPDHFRCNNGR 2746
Query: 991 --RFHRTCSDINECAEFGYCD-QLCAN 1062
+ TC+ ++CA+ D +LC N
Sbjct: 2747 CIERNLTCNVNDDCADGSDEDIRLCRN 2773
Score = 147 bits (371), Expect = 7e-33
Identities = 113/417 (27%), Positives = 169/417 (40%), Gaps = 55/417 (13%)
Frame = +1
Query: 121 IISASVNTASSVCNENDFRCNDG-KCIRTEWXXXXXXXXXXXXXXXXX-PHPGCKSDQWQ 294
I++A + ++ C+ F+C KCI W P C++ Q+Q
Sbjct: 3205 ILTADGKSCAANCSAAHFQCRTTFKCIPFYWRCDKQDDCGDGSDEPPNCPTFTCEAGQFQ 3264
Query: 295 CDTYTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQ------C 456
C + CI Q CD + C D SDE+DC +C S + F C C
Sbjct: 3265 C-----LNKRCINPSQICDGVDQCGDLSDERDC--DRFECFSSH-FKCGPSAAKNTSGFC 3316
Query: 457 FDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDG-------- 612
+ +++CD + +C + DE++ +N TA QFRCA+ +CI ++WVCD
Sbjct: 3317 IEGARRCDEEVNCPNGEDEQNCEPKNCTAT---QFRCANGGRCIDRTWVCDNVPDCHDGS 3373
Query: 613 --------------------------------SKDCADGSDEPDTC---EFKKCTANEFQ 687
KDCA+G DE + C E C F+
Sbjct: 3374 DEQVCGPATTCPEHEFRCSEGRCIPQSWLCDDEKDCANGEDETENCQKPEAITCEPTSFR 3433
Query: 688 CKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCA 867
C N +C P ++RCD+ +DCGDNSDE C C ++ C GHCI ++ CD +CA
Sbjct: 3434 CNNSKCIPGRWRCDFENDCGDNSDELNCELRNCSESEFRC-RDGHCIRGIRRCDNEFNCA 3492
Query: 868 DGADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYK-LDDRFHRTCSDINECAEFGYC 1044
D +DE+ C+ C + + HP+ + C +D+ C EC E Y
Sbjct: 3493 DHSDEENCNVT-CSAEQFKCKSHPACISNKFKCDGDNDCIDESDEEDC----ECQEGEY- 3546
Query: 1045 DQLCANHR---PGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARR 1206
C N + + C + DC E G YC + +K A R
Sbjct: 3547 --RCNNGKCILSSWVCDGIDDCLDNSDEMGE---------YCKEHGCNKRAFRCANR 3592
Score = 144 bits (364), Expect = 5e-32
Identities = 170/727 (23%), Positives = 296/727 (40%), Gaps = 45/727 (6%)
Frame = +1
Query: 4303 CEPENECLDSSSCSQRCKD-EKHGFTCSCDEGYELDV----------DKRTCKVADNVKD 4449
C+ N+ + C C C C GY D D V +K
Sbjct: 1705 CQKRNDKSAGTGCEHLCIPVSAQSHVCRCAIGYRSDPRNPWRCIGLDDILVYSVGHQLKG 1764
Query: 4450 TRIYVSNRNRIYYSDHKLDNWHTFGAIVENAIALA--WDSLTDRIYWSDIREKKILSANR 4623
+ S+ S L N + G + + ++A + +D D +Y +D I R
Sbjct: 1765 IALSSSDE-----STGSLRNRESLGPLQQISLATSIDFDVAHDYVYIADTDRGSITRIKR 1819
Query: 4624 NGTNATVFIA------DG--LDITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLL 4779
+G+ V I+ DG LD GIA+DWV N+YW D N IEVA L + +
Sbjct: 1820 DGSAREVIISNFEQVVDGSTLDWLGGIAIDWVAENIYWTDQKRNLIEVARLNGTLR--YV 1877
Query: 4780 VHQNVSQPRGIAVDPRKGVMFWTDWGQNPCIERASMDGTDRQIIVKTKIYWPNTIALDYT 4959
V +V P+ +A+DP +G +F+ G I R +DG+ I+V + + +ALD
Sbjct: 1878 VASDVESPQLLAIDPIQGYLFYVTRG---TIGRMGLDGSGNFILV-NRSSAISDLALDLD 1933
Query: 4960 TDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVY 5139
VY+ ++ D I V+YDG+ + +L + +P +L +F D +Y++D R
Sbjct: 1934 NQVVYWCETSTDTIWKVDYDGNLKRLLLNGTS--HNPKSLDLFGDSIYWADSRGN----- 1986
Query: 5140 PKYPNGTTSEYPSHTFSKALGVVAVHPV----LQPVIKNNPC--STNPCSHLCLLNNKNT 5301
Y G ++ + + +AL V ++ + + K N C S C LCL N +
Sbjct: 1987 -IYEAGLSNIFNYRSVVEALEVSSLKDIKVFSSRKQSKTNACGVSNGGCQELCLFNGTHP 2045
Query: 5302 FTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNVFGIEMNSASEKETPVLAGMVPLSGLG 5481
C C G K+ ++ K + + FL+ +++ + I M A+ P+ + S L
Sbjct: 2046 I-CACSHG-KISSADLKTCEPYENFLIFSRQSAIESIHMTDANNINGPI-PEIKNSSYLK 2102
Query: 5482 NAFDAAYDALSEEMFI--LEH----------TNHAKTLA-QITTDSAIYRSTVNGGNKTK 5622
N +YD + +F ++H TNH + + Q+T + + T+
Sbjct: 2103 NTIALSYDYEQQLIFYSDIDHSTINCVFFNGTNHRRIVTKQLTVEGLAFNVL------TR 2156
Query: 5623 MFSSAVPDDAYCLGFDWNGRNL---VVGNKITQTIEIIRTQGKQYRSVILSNDQSXXXXX 5793
+ ++A D N +L ++ Q + +R K R + +
Sbjct: 2157 VLFWTSNNEAAIRSLDLNKASLTDPAANAELVQDVIKLRATDKP-RGIAVE--------- 2206
Query: 5794 XXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAIDTTNTR 5973
V+W + A A + RA G I ++D+ + + +D +
Sbjct: 2207 --------PCLAMVYWTNWNQHA--ASIQRAYPSGYGLESIITSDIQMPNALTLDYQARK 2256
Query: 5974 VYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAFDSIEVATINGD 6153
+Y+++A ++ YDG+ R + + P LA +GD LF+ D ++ A
Sbjct: 2257 LYWADALLDKVERTDYDGKHRVVLAHSTPKHPFALAVFGDLLFWTDLTVHAVIRANKYSG 2316
Query: 6154 SQPPQWTHFKKDVENLANIKALQP-RASSSGHPCHINNGNCDHICIPLMFAQRTCTCANG 6330
S ++D+ I A+Q S PC + NG C+ +C+ + C C G
Sbjct: 2317 S---DIVLLRRDIAQPMGIVAVQQIDKECSADPCQVMNGFCEDVCLIDAAGKVECHCTQG 2373
Query: 6331 YV-KDGQ 6348
+ DGQ
Sbjct: 2374 VLAADGQ 2380
Score = 143 bits (361), Expect = 1e-31
Identities = 110/386 (28%), Positives = 185/386 (47%), Gaps = 27/386 (6%)
Frame = +1
Query: 4282 QLVNKTKCEPENEC-LDSSSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRI 4458
++ + K N C + + C + C C+C G D +TC+ +N
Sbjct: 2014 KVFSSRKQSKTNACGVSNGGCQELCLFNGTHPICACSHGKISSADLKTCEPYEN-----F 2068
Query: 4459 YVSNRNRIYYSDHKLDNWHTFGAIVE--------NAIALAWDSLTDRIYWSDIREKKILS 4614
+ +R S H D + G I E N IAL++D I++SDI I
Sbjct: 2069 LIFSRQSAIESIHMTDANNINGPIPEIKNSSYLKNTIALSYDYEQQLIFYSDIDHSTINC 2128
Query: 4615 ANRNGTNATVFIADGLDITEGIALDWVGRNLYWV---DSSLNTIEV--ANLEDPKQRTLL 4779
NGTN + L + EG+A + + R L+W ++++ ++++ A+L DP L
Sbjct: 2129 VFFNGTNHRRIVTKQLTV-EGLAFNVLTRVLFWTSNNEAAIRSLDLNKASLTDPAANAEL 2187
Query: 4780 VHQNVS-----QPRGIAVDPRKGVMFWTDWGQNPC-IERASMDGTDRQIIVKTKIYWPNT 4941
V + +PRGIAV+P +++WT+W Q+ I+RA G + I+ + I PN
Sbjct: 2188 VQDVIKLRATDKPRGIAVEPCLAMVYWTNWNQHAASIQRAYPSGYGLESIITSDIQMPNA 2247
Query: 4942 IALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFEDMMYYSDRRL 5121
+ LDY ++Y+AD+ LD ++ +YDG R VLA S +HP ALA+F D+++++D +
Sbjct: 2248 LTLDYQARKLYWADALLDKVERTDYDGKHRV-VLAHST-PKHPFALAVFGDLLFWTDLTV 2305
Query: 5122 QKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTNP-------CSHLC 5280
+ KY +G+ ++ +G+VAV + + CS +P C +C
Sbjct: 2306 HAVIRANKY-SGSDIVLLRRDIAQPMGIVAVQQI------DKECSADPCQVMNGFCEDVC 2358
Query: 5281 LLNNKNTFTCKCPMGEKLDASGKKCI 5358
L++ C C G L A G++CI
Sbjct: 2359 LIDAAGKVECHCTQG-VLAADGQRCI 2383
Score = 143 bits (360), Expect = 1e-31
Identities = 159/712 (22%), Positives = 298/712 (41%), Gaps = 23/712 (3%)
Frame = +1
Query: 6217 LQPRASSSGHPCHINN-GNCDHICIPLMFAQRTCTCANGY-VKDGQTSCKLF--DESFVI 6384
LQP GH +N G C IC R C C GY + + +C+ D +VI
Sbjct: 1095 LQPNGRDCGHDHACDNWGTCSQICTKAGTHYR-CGCVEGYTLMYDKFTCRSNNGDSPYVI 1153
Query: 6385 VATKTKVIGYPIDETQSKGVAMEPIGGLSITGVDYDYESKTIYVAEASGINKGITAYTIG 6564
+ + +++G ++ + GV + +D+ Y ++++ + + ++ I T+
Sbjct: 1154 FSNRQEILGVDLN---TLGVRSFYTSLRNTIALDFLYRNESVQIFWSDVMDDKIYRGTLR 1210
Query: 6565 E---SSPRAVIRDSIGSLTIKSLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTT 6735
S+ AV++ + T + LA+DWI N+Y+I D+ IEV+K +G++R+ L+
Sbjct: 1211 NDTLSNVEAVVQSGLS--TAEGLAVDWIGMNIYWI--DSNLDQIEVAKTNGSFRRTLVAG 1266
Query: 6736 KTETPSSIAVDPVSRYLYWAD-QGQKPTIQRSFLDGSRREVI--VSSGIAEPTDLVVDVA 6906
P +IA+DP+ L+W D + P ++R + G R VI V S P + +D
Sbjct: 1267 DMVNPRAIALDPMEGVLFWTDWEEGSPRLERCTMAGENRTVIKYVGSDGGWPNGIALDYI 1326
Query: 6907 SKMIYWSDAKMDGIYRVRSTGGTPELVRSD---IASAAGVALHGQNMYWTDNRLEKLFRA 7077
+ +YW DA+ D I+ + G LV D +A + + +YWTD R + RA
Sbjct: 1327 PRRVYWIDARSDSIHTITYDGQDHHLVIKDQGVLAHPFSITVFDNYVYWTDWRTYSVIRA 1386
Query: 7078 TSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRAS-SPCQITDNLRKSPCTQLCFAT 7254
+K N T + + T + + + S+ QP +PC DN C+ LC +
Sbjct: 1387 -NKWNGTDVNVIQKTQSQPF----GIQILHSSRQPNTQPNPC--ADN--NGGCSHLCLLS 1437
Query: 7255 PGTQTPTCSCARGVL---KGRTCEEPDTYIMFSDGDKIIDVAIEPDVKASRPLKDPFPEI 7425
G++ C+C + R C + ++F +I V ++ + P ++
Sbjct: 1438 VGSR-HECACPHVMRLHEDRRQCVPNEEILLFVVLTEIRGVDLQQPAHYTIPTISHQTQV 1496
Query: 7426 SNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAENPRLVFGASKQPHAKEIRHISDMK 7605
D D++ R+Y+ + +N ++ L G + +I +
Sbjct: 1497 VQPAVLDYDISAARLYW----------NDIQLNEIKSSGLATGPIETILDTDISNSLGFA 1546
Query: 7606 LDWLTQKIYFTTGR--GGKVMAIDTAGEHLSTIASGDWTYALAIDPCSGLLFWSDSGYKT 7779
+DW+++ +YF+TG ++M + GE ++ IA G + + L+ Y T
Sbjct: 1547 VDWISKLLYFSTGNETHSRIMVSNLNGEFVTEIADG-------LSVVNSLVV-----YPT 1594
Query: 7780 SGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVDFRNQKIYWADVNRLNIEVADY-DG 7956
S + P ++A+DF ++Y+ N I D G
Sbjct: 1595 SNSTFHP----------------------IDSLALDFETNRLYYISSNAGEINYYDIGSG 1632
Query: 7957 QNRKVIA---SGYRAKSLDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVSDRRIPGALR 8127
+ +V+A + ++ I+ +Y D + R +K +V ++ A+R
Sbjct: 1633 KIIQVLAPHEDNHPISTITIYRDSIYYDDNHDGRIMRCNKNLCQNPVSVRNNTSGLNAIR 1692
Query: 8128 VFASESDVRTRNQVCNALTSQLCKTDNGGCDQLCTVVADDIGLAASKVQCSC 8283
++ + T N+ + K+ GC+ LC I ++A C C
Sbjct: 1693 MYHPGAQSGT-----NSCQKRNDKSAGTGCEHLC------IPVSAQSHVCRC 1733
Score = 126 bits (316), Expect = 2e-26
Identities = 161/686 (23%), Positives = 261/686 (37%), Gaps = 42/686 (6%)
Frame = +1
Query: 9781 QKSCHNVNECYEGISGCSQKCDD---KIGSY--KCGCVDGYQLSSDDHSCKRTEMEPEPF 9945
QK + C GC Q C KIG +C C GY+L + + P
Sbjct: 502 QKQPEVAHPCRIQNGGCDQLCIPVWKKIGVAIAQCMCSPGYRLKTKSQCV----LIKRPT 557
Query: 9946 FLL---ANKHYIRKISIDGNKYELAAQGFDNV---VSLDIDLTEKKAY----LIDQGKLR 10095
FLL +N IR ++ G K + A ++ ++ D + ++ + +ID+ R
Sbjct: 558 FLLYAKSNPAMIRGFAV-GIKSQEAIVPITDLGPHITFDYHVEDQLIFFSHGVIDKPSFR 616
Query: 10096 LLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCK 10275
+ LD + +L + +GI+ DW+G ++ + I V +L + +
Sbjct: 617 IEAQKLD------GTQRELLLESPGSCDGISYDWLGNNIFWTDSDRNHISVIKLGPKRMR 670
Query: 10276 TLIRDRIQQPKAIVVHPGKGYLFFTEWSLQP-YIGRIALDGS-PELQDPIFKLAEHDLGW 10449
+ ++ PK+IVV P +G+++++ WS+ I R ++G+ PEL + E + W
Sbjct: 671 YTVLRQLYAPKSIVVDPKQGWMYWSSWSVPSGRIDRAWMNGTQPEL---LVSSKERPIEW 727
Query: 10450 PNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHIPAQRTSHVS--SMVVFDDYLYWAD 10623
P ++ID RL+W DA L+ I ++ DG+ R + R+ + ++ V LY+AD
Sbjct: 728 PTGLSIDMIQKRLYWCDARLSFIESINLDGSNRVLLFDGRSQNQFPVALAVHRQLLYFAD 787
Query: 10624 WNLREVLRCDKWTGKNETILKK-TVQLPN--DLRIVHPMRQPAYPNPCGDNNGGCSHLC- 10791
N++ + +K + +L+ T++ P L+I + Q G+ C C
Sbjct: 788 -NVKGHI--EKLNLSDPHLLETITIEKPQVLGLKIFDNLTQYG-----GNGRNACEIDCP 839
Query: 10792 --LIGAGGNGYTCSCPDQFVLLSDQK----TCEP--------NCTERQFACGGDDAKCIP 10929
+ +C C D VL + C P +C + CI
Sbjct: 840 GICLNTPVAVASCKCEDGQVLSLSSEGKPVACVPFDLQHSLASCNNSTHFLCRNKIDCIE 899
Query: 10930 KLWYCDGEPDCRDGSDE--PGESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXX 11103
+ CDG+ DC DGSDE + C F+C C +
Sbjct: 900 IKYTCDGDRDCEDGSDEETTPDGPCDPNCDLERNFKCDEQRCISRSHVCDGSVDCIDESD 959
Query: 11104 EQ--NC-DKACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEADTLCMSAERNCTAEEF 11274
E NC +K C F+C + RCIP + +D +D E EF
Sbjct: 960 EDYINCPNKTCSEHFFQCEVSHRCIPNTWV-CDRHLDCGPNDSSD----EPEHCHKCPEF 1014
Query: 11275 RCNNNKCIAKAWRXXXXXXXXXXXXETPECAQIECKKGWTRCSSSYRCIPNWAFCNGQDD 11454
C N+ C+ + C G C + +CI CNG+ D
Sbjct: 1015 ECKNSACVP---------------------FEFLC-DGVDNCGVTNQCIKVTQLCNGRTD 1052
Query: 11455 CRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPC 11634
C D +DE FRCA +CD NDC S + G C
Sbjct: 1053 CPDGTDEG------------FRCAEK--------LCDAPNDC---SHACHNAPEGLICSC 1089
Query: 11635 SESEFRCNDGKCIPGSKVCDGTIQCS 11712
F +G+ CD CS
Sbjct: 1090 PAHLFLQPNGRDCGHDHACDNWGTCS 1115
Score = 119 bits (298), Expect = 2e-24
Identities = 73/234 (31%), Positives = 118/234 (50%), Gaps = 8/234 (3%)
Frame = +1
Query: 4672 EGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTD 4851
+GI+ DW+G N++W DS N I V L PK+ V + + P+ I VDP++G M+W+
Sbjct: 638 DGISYDWLGNNIFWTDSDRNHISVIKL-GPKRMRYTVLRQLYAPKSIVVDPKQGWMYWSS 696
Query: 4852 WG-QNPCIERASMDGTDRQIIVKTK---IYWPNTIALDYTTDRVYFADSKLDFIDFVNYD 5019
W + I+RA M+GT +++V +K I WP +++D R+Y+ D++L FI+ +N D
Sbjct: 697 WSVPSGRIDRAWMNGTQPELLVSSKERPIEWPTGLSIDMIQKRLYWCDARLSFIESINLD 756
Query: 5020 GSGRTQVLASSKFVQHPHALAIFEDMMYYSDR---RLQKLQVY-PKYPNGTTSEYPSHTF 5187
GS R + Q P ALA+ ++Y++D ++KL + P T E P
Sbjct: 757 GSNRVLLFDGRSQNQFPVALAVHRQLLYFADNVKGHIEKLNLSDPHLLETITIEKP---- 812
Query: 5188 SKALGVVAVHPVLQPVIKNNPCSTNPCSHLCLLNNKNTFTCKCPMGEKLDASGK 5349
+ LG+ + Q C +CL +CKC G+ L S +
Sbjct: 813 -QVLGLKIFDNLTQYGGNGRNACEIDCPGICLNTPVAVASCKCEDGQVLSLSSE 865
Score = 96.3 bits (238), Expect = 2e-17
Identities = 66/256 (25%), Positives = 118/256 (45%), Gaps = 8/256 (3%)
Frame = +1
Query: 7600 MKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTIASGDWTY--ALAIDPCSGLLFWSDSGY 7773
+ +DW+ IY+ ++ T G T+ +GD A+A+DP G+LFW+D
Sbjct: 1231 LAVDWIGMNIYWIDSNLDQIEVAKTNGSFRRTLVAGDMVNPRAIALDPMEGVLFWTDWEE 1290
Query: 7774 KTSGGLYEPRIERSNLAGGSRKVI--VSESISLPAAIAVDFRNQKIYWADVNRLNIEVAD 7947
+ PR+ER +AG +R VI V P IA+D+ +++YW D +I
Sbjct: 1291 GS------PRLERCTMAGENRTVIKYVGSDGGWPNGIALDYIPRRVYWIDARSDSIHTIT 1344
Query: 7948 YDGQNRKVIA--SGYRAK--SLDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVSDRRIP 8115
YDGQ+ ++ G A S+ ++D ++Y +D + V R +K +G+ + + + P
Sbjct: 1345 YDGQDHHLVIKDQGVLAHPFSITVFDNYVYWTDWRTYSVIRANKWNGTDVNVIQKTQSQP 1404
Query: 8116 GALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLCTVVADDIGLAASKVQCSCNDTY 8295
+++ S T+ C +NGGC LC + S+ +C+C
Sbjct: 1405 FGIQILHSSRQPNTQ--------PNPCADNNGGCSHLCLL------SVGSRHECACPHVM 1450
Query: 8296 ELVQEPGKDYPTQCVL 8343
L ++ + P + +L
Sbjct: 1451 RLHEDRRQCVPNEEIL 1466
Score = 92.4 bits (228), Expect = 3e-16
Identities = 54/152 (35%), Positives = 64/152 (41%), Gaps = 12/152 (7%)
Frame = +1
Query: 11494 TCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCN-DGKC 11670
TC +F C GKCIP W CDT DC D SDE+ C+E F C +C
Sbjct: 2 TCSQ-SQFTCVMDGKCIPALWRCDTSADCSDGSDEVGCD---KAHACNEGMFHCTVSNRC 57
Query: 11671 IPGSKVCDGTIQCS--------DGLDESQCTLR---RCLPGHRQCDDGTCIAEHKWCDRK 11817
IP CDG + C D DE R +CLP C DG C+ ++CD
Sbjct: 58 IPHDWTCDGDVDCGLVEKYDMVDVSDEDPQLCRAHTKCLPTQALCSDGKCLEIDRFCDGA 117
Query: 11818 KDCPNAADELHCEDVSRRTCSPFEFECANSVC 11913
DC N DEL+C T S C C
Sbjct: 118 WDCSN--DELNCSSNDTATASAPTSACDALKC 147
Score = 88.2 bits (217), Expect = 5e-15
Identities = 64/217 (29%), Positives = 88/217 (40%), Gaps = 13/217 (5%)
Frame = +1
Query: 11872 TCSPFEFECA-NSVCIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLN 12048
TCS +F C + CIP + SDE C A F C S C+
Sbjct: 2 TCSQSQFTCVMDGKCIPALWRCDTSADCSDGSDEVG--CDKAHACNEGMFHCTVSNRCIP 59
Query: 12049 ILQLCNGFNDCG------PNDFSDEHLSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDR 12210
C+G DCG D SDE +C + ++ C Q C++GKC+ CD
Sbjct: 60 HDWTCDGDVDCGLVEKYDMVDVSDEDPQLCRAHTK---CLPTQALCSDGKCLEIDRFCDG 116
Query: 12211 KDDCGDASDEIGCSKHGGKTS------CEAFGNNGGCKHICTDVRDGFYCHCRDGFRPDP 12372
DC ++DE+ CS + T+ C+A C + C +G C C +P+
Sbjct: 117 AWDC--SNDELNCSSNDTATASAPTSACDALK----CSYDCRLTSEGARCFCAKDSQPNG 170
Query: 12373 QSPKECIDIDECAGNNTCTQLCLNTKGSYLCRCHEDY 12483
C D DEC C Q+C N G+Y C C Y
Sbjct: 171 SV---CEDFDECQIEGLCDQMCKNQPGAYQCSCTTGY 204
Score = 88.2 bits (217), Expect = 5e-15
Identities = 59/175 (33%), Positives = 76/175 (42%), Gaps = 11/175 (6%)
Frame = +1
Query: 11413 RCIPNWAFCNGQDDCRDNSDEDKQRCP--TCDDVGEFRCATSGKCIPRRWMCDTENDCG- 11583
RCI C+G DC D SDED CP TC + F+C S +CIP W+CD DCG
Sbjct: 940 RCISRSHVCDGSVDCIDESDEDYINCPNKTCSE-HFFQCEVSHRCIPNTWVCDRHLDCGP 998
Query: 11584 -DNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTLRRCLPG 11760
D+SDE + C EF C + C+P +CDG C G+ + + G
Sbjct: 999 NDSSDEPE-----HCHKC--PEFECKNSACVPFEFLCDGVDNC--GVTNQCIKVTQLCNG 1049
Query: 11761 HRQCDDGT---CIAEHKWCDRKKDCP----NAADELHCEDVSRRTCSPFEFECAN 11904
C DGT K CD DC NA + L C + P +C +
Sbjct: 1050 RTDCPDGTDEGFRCAEKLCDAPNDCSHACHNAPEGLICSCPAHLFLQPNGRDCGH 1104
Score = 84.3 bits (207), Expect = 8e-14
Identities = 55/173 (31%), Positives = 74/173 (41%), Gaps = 12/173 (6%)
Frame = +1
Query: 11371 IECKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDE-DKQRCPTCDDVGEFRCATSGKCIP 11547
+ C + C +CIP C+ DC D SDE + C++ G F C S +CIP
Sbjct: 1 VTCSQSQFTCVMDGKCIPALWRCDTSADCSDGSDEVGCDKAHACNE-GMFHCTVSNRCIP 59
Query: 11548 RRWMCDTENDCG--------DNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTI 11703
W CD + DCG D SDE C T+ C ++ C+DGKC+ + CDG
Sbjct: 60 HDWTCDGDVDCGLVEKYDMVDVSDEDPQLCRAHTK-CLPTQALCSDGKCLEIDRFCDGAW 118
Query: 11704 QCSDGLDESQCTLRRCLPGHRQCDDGTCIAEHKWCDRKK---DCPNAADELHC 11853
CS+ DE C+ D T A CD K DC ++ C
Sbjct: 119 DCSN--DELNCSSN---------DTATASAPTSACDALKCSYDCRLTSEGARC 160
Score = 84.3 bits (207), Expect = 8e-14
Identities = 59/212 (27%), Positives = 78/212 (35%), Gaps = 41/212 (19%)
Frame = +1
Query: 397 ASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADK 576
A V+C + ADG++C S +CS + +C
Sbjct: 2363 AGKVECHCTQGVLAADGQRCIPKSVS---------------NCSSSEFSC--------TN 2399
Query: 577 TQCIQKSWVCDGSKDCADGSDEPDT-CEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDN 753
CI CDG K+C DGSDE T C + C F+C N RC P+ +C++ +CGD
Sbjct: 2400 GNCIPFHLTCDGVKNCLDGSDELVTFCAHRPCPDGFFRCNNARCIPKNQQCNHIQNCGDG 2459
Query: 754 SDEDECG-----EYRCPPGKW---------------------------------NCPGTG 819
SDE C +RC G+ NC T
Sbjct: 2460 SDEVGCSCNNATHFRCTDGQCIVKSMRCDYEPDCKDVSDEIGCPVMRNCTEGFVNCANTT 2519
Query: 820 HCIDQLKLCDGSKDCADGADEQQCSQNL--CP 909
C CDG DC D +DEQ C + CP
Sbjct: 2520 GCYMPTWRCDGENDCWDNSDEQDCPTAIPTCP 2551
Score = 81.3 bits (199), Expect = 7e-13
Identities = 58/203 (28%), Positives = 81/203 (39%), Gaps = 32/203 (15%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQ 453
C Q+ C CI RCD DC+DGSDE C ++ +F C +
Sbjct: 3 CSQSQFTCVM----DGKCIPALWRCDTSADCSDGSDEVGC--DKAHACNEGMFHCTVSNR 56
Query: 454 CFDVSKKCDG--------KYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCD 609
C CDG KYD D+SDE R HT C Q C+D +C++ CD
Sbjct: 57 CIPHDWTCDGDVDCGLVEKYDMVDVSDEDPQLCRAHTKCLPTQALCSD-GKCLEIDRFCD 115
Query: 610 GSKDC------------ADGSDEPDTCEFKKCTAN-EFQCKNKRC------QPRKFRCDY 732
G+ DC A S C+ KC+ + + RC QP C+
Sbjct: 116 GAWDCSNDELNCSSNDTATASAPTSACDALKCSYDCRLTSEGARCFCAKDSQPNGSVCED 175
Query: 733 YDDCG-----DNSDEDECGEYRC 786
+D+C D +++ G Y+C
Sbjct: 176 FDECQIEGLCDQMCKNQPGAYQC 198
Score = 80.9 bits (198), Expect = 9e-13
Identities = 86/362 (23%), Positives = 144/362 (39%), Gaps = 19/362 (5%)
Frame = +1
Query: 9802 NECYEGISGCSQKCDDKIGS-YKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRK 9978
N C + GCS C +GS ++C C +L D C + E L IR
Sbjct: 1421 NPCADNNGGCSHLCLLSVGSRHECACPHVMRLHEDRRQC----VPNEEILLFVVLTEIRG 1476
Query: 9979 ISIDGNK-YELAAQGFDNVVS----LDIDLTEKKAYLIDQGKLRLLRVDLDEMDSP---L 10134
+ + Y + V LD D++ + Y D + L+E+ S
Sbjct: 1477 VDLQQPAHYTIPTISHQTQVVQPAVLDYDISAARLYWND--------IQLNEIKSSGLAT 1528
Query: 10135 SSYETVLRHNVYGTEGIAVDWVGRKLYML--NRQERSIRVCELDGRFCKTLIRDRIQQPK 10308
ET+L ++ + G AVDW+ + LY N I V L+G F T I D +
Sbjct: 1529 GPIETILDTDISNSLGFAVDWISKLLYFSTGNETHSRIMVSNLNGEFV-TEIADGLSVVN 1587
Query: 10309 AIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRL 10488
++VV+P F PI +++A+D+ ++RL
Sbjct: 1588 SLVVYPTSNSTF----------------------HPI-----------DSLALDFETNRL 1614
Query: 10489 FWGDAHLNEIGFMDFDGNGR---RHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKW 10659
++ ++ EI + D G+G+ P + +S++ ++ D +Y+ D + ++RC+K
Sbjct: 1615 YYISSNAGEINYYDI-GSGKIIQVLAPHEDNHPISTITIYRDSIYYDDNHDGRIMRCNKN 1673
Query: 10660 TGKNETILKKTVQLPNDLRIVHPMRQPAYPNPCGDNNG-----GCSHLCLIGAGGNGYTC 10824
+N ++ N +R+ HP Q N C N GC HLC I + C
Sbjct: 1674 LCQNPVSVRNNTSGLNAIRMYHPGAQSG-TNSCQKRNDKSAGTGCEHLC-IPVSAQSHVC 1731
Query: 10825 SC 10830
C
Sbjct: 1732 RC 1733
Score = 77.8 bits (190), Expect = 7e-12
Identities = 69/269 (25%), Positives = 104/269 (38%), Gaps = 13/269 (4%)
Frame = +1
Query: 11140 FKCAATGRCIPRRFTXXXXXXXXXRSDEADTLCMSAERNCTAEE-FRCNNNKCIAKAWRX 11316
F C CI ++T SDE T + NC E F+C+ +CI+++
Sbjct: 889 FLCRNKIDCIEIKYTCDGDRDCEDGSDEETTPDGPCDPNCDLERNFKCDEQRCISRSHVC 948
Query: 11317 XXXXXXXXXXXETP-ECAQIECKKGWTRCSSSYRCIPNWAFCNGQDDCRDN-SDEDKQRC 11490
E C C + + +C S+RCIPN C+ DC N S ++ + C
Sbjct: 949 DGSVDCIDESDEDYINCPNKTCSEHFFQCEVSHRCIPNTWVCDRHLDCGPNDSSDEPEHC 1008
Query: 11491 PTCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSD--ELDASCGGTTRPC---SESEFRC 11655
C EF C S C+P ++CD ++CG + ++ C G T C ++ FRC
Sbjct: 1009 HKCP---EFECKNSA-CVPFEFLCDGVDNCGVTNQCIKVTQLCNGRT-DCPDGTDEGFRC 1063
Query: 11656 NDGKCIPGSKVCDGTIQCSDGLDESQCTLRRCLPGH--RQCDDGTCIAEH---KWCDRKK 11820
K+CD CS + L P H Q + C +H W +
Sbjct: 1064 -------AEKLCDAPNDCSHACHNAPEGLICSCPAHLFLQPNGRDCGHDHACDNWGTCSQ 1116
Query: 11821 DCPNAADELHCEDVSRRTCSPFEFECANS 11907
C A C V T +F C ++
Sbjct: 1117 ICTKAGTHYRCGCVEGYTLMYDKFTCRSN 1145
Score = 69.7 bits (169), Expect = 2e-09
Identities = 52/189 (27%), Positives = 72/189 (37%), Gaps = 2/189 (1%)
Frame = +1
Query: 8497 SCPEDYNLCT-NRRCIDSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCS-NGHCINQT 8670
+C + C + +CI + +C+ DC DGSDE+ C A AC EG F C+ + CI
Sbjct: 2 TCSQSQFTCVMDGKCIPALWRCDTSADCSDGSDEVGCDKAHACNEGMFHCTVSNRCIPHD 61
Query: 8671 KVCDGHNDCHDEQVSDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKAD 8850
CDG DC L + YD +
Sbjct: 62 WTCDGDVDC-------------------------------------GLVEKYDMVDVSDE 84
Query: 8851 ENQLFCMNQQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDY 9030
+ QL + +C C G+C+ CDG DCS+ DE + + DTA
Sbjct: 85 DPQLCRAHTKCLPTQALCSDGKCLEIDRFCDGAWDCSN--DELNCSSNDTATASAPTS-- 140
Query: 9031 LFQCDNLKC 9057
CD LKC
Sbjct: 141 --ACDALKC 147
Score = 65.9 bits (159), Expect = 3e-08
Identities = 137/653 (20%), Positives = 227/653 (33%), Gaps = 74/653 (11%)
Frame = +1
Query: 7231 CTQLCFATPGTQTPTCSCARGVLKGRTCEEPDTYIMFSDGDKIIDVAIEPDVKASRPLKD 7410
C+QLC G T C CA G +KG + G I+ VA E D R L
Sbjct: 3666 CSQLCIEKKGHYT--CRCAEGYVKGGPGRNATCVAVDEQG--ILLVASESDF---RSLYA 3718
Query: 7411 PFPEISNLQT-------FDVDVNLRRVYFVVESPVGVNISWFSMNN--------AENP-- 7539
P + LQT FD + + +I+ M+ + +P
Sbjct: 3719 DTPVMGYLQTSSLKIDRFDFAITRHNITLFWIDSYDTSINKILMDTTVKDGGDYSRSPPV 3778
Query: 7540 ------RLVFGASKQP------------HAKEIR-----HISDMKLDWLTQKIYFTTGRG 7650
R G + P H+ + H + DWLT+++Y +
Sbjct: 3779 DKRKIVRRGLGPAPAPPSYDRIKTLDGKHSSVVLKDDEIHPIAIACDWLTERLYVINKKR 3838
Query: 7651 GKVMAIDTAG-EHLSTIASGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAG 7827
+ + G H + A+G L +DP SG++ WS I S + G
Sbjct: 3839 SNIFVMSFNGTNHTTLTATGKHPIDLVVDPVSGMMVWS----------IMETIISSGMDG 3888
Query: 7828 GSRKVIVSESISLPAAIAVDFRNQKIYWADVNRLNIEVA-DYDGQNRKVIASGY---RAK 7995
++ +V ++ + +A+D +++YWAD + IE G +R VIA + + K
Sbjct: 3889 RGKQKLVHTNVEWASGLAIDTTTKRLYWADYRKSTIETCLLLTGGDRHVIAELHDYSKPK 3948
Query: 7996 SLDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESDV------RT 8157
LD+++ +Y+ + + +++K + + R G L + S SDV +
Sbjct: 3949 LLDVFEDSVYVI-LYNQNILKLNKYGRDNGTYMNEEARGAGGLAGYRS-SDVHFIHPLKH 4006
Query: 8158 RNQVCNALTSQLCKTDNGGCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQC 8337
V N C N L TV + K C C D + + +C
Sbjct: 4007 DRSVPNPCIISPC--HNSTVCLLSTV-------SRLKRACVCPDARPRIVFDERGEVKEC 4057
Query: 8338 VLRGSNSEPAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCP---E 8508
+ PA+ P C +G+C + D + C ++ + YC+ C +
Sbjct: 4058 L-----DLPAQ--APECKLHCNNGTCFI---DTDGQQKCKCSASFDGKYCDHYICSGYCK 4107
Query: 8509 DYNLC---------------TNRRCIDSAKKCNHIDDCGDGSD----ELDCPS-AVACAE 8628
+ C T +RC S KC C +G + + D S + +C
Sbjct: 4108 NKGFCELVNGEPQCTCLPQWTGKRCDISTNKCQRY--CHNGGNCTIVQRDGGSLSCSCPV 4165
Query: 8629 GTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPGLPIDCRGVKVRCPNTNICIQPA 8808
G HC N C+ C + +D S C G R N+C
Sbjct: 4166 GYTGEQCEHCSNLR--CENGGVCR-KTTTDRSQCLC------AEGYVGRNCEKNVC---T 4213
Query: 8809 DLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCIPETWQCDGDNDCSDG 8967
+ C+ +C + + C + RC +C C DC G
Sbjct: 4214 EFCENGGECTIERGAAKCSCPENTYGE---RCQLRQCAD---LCRNGGDCVPG 4260
Score = 65.9 bits (159), Expect = 3e-08
Identities = 82/353 (23%), Positives = 141/353 (39%), Gaps = 11/353 (3%)
Frame = +1
Query: 5263 PCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNVFGIEMNSASEKET 5442
PC+ C+ N ++ C C G L C + + I+ +F N +E
Sbjct: 2867 PCTQTCV-NTHGSYHCTCLDGFVL-RDNDTCRAEGRH---ILPPKLIFS---NRYYLREV 2918
Query: 5443 PVLAGMVPLS-GLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNGGNKT 5619
+ GM L+ L NA +D +E + T + +S V ++T
Sbjct: 2919 DLSGGMTILAHNLTNAITLDFD-WKDECYYWSDVTRTVTTVKRMCESGEENRPVEVIHRT 2977
Query: 5620 KMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVILSNDQSXXXXXXX 5799
+ + P+ L DW GRNL +K TIE+ + G+ YR V+++ +
Sbjct: 2978 NLKN---PEG---LAVDWVGRNLYWCDKGLDTIEVSKLDGR-YRRVLINKELQKPRAIAL 3030
Query: 5800 XXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAIDTTNTRVY 5979
+ Y++W D G + RAG+DGSN ++ L + + I +++
Sbjct: 3031 DPY-----RRYMYWTDWGD---QPHIGRAGMDGSNQTILIKEQLGWPNALTISFETNQLF 3082
Query: 5980 FSEAKAGRISSVTYDGQDRHYVLSDGGRQPN-------GLAFYGDRLFYADSAFDSIEVA 6138
+ +A+ I+ DGQ+ +LS RQP +A + DR++++D SIE
Sbjct: 3083 WGDAREDYIAVSDLDGQNVRILLS-RARQPTLNLHHVFAIAVWEDRIYWSDLDSKSIEYC 3141
Query: 6139 -TINGDSQPP--QWTHFKKDVENLANIKALQPRASSSGHPCHINNGNCDHICI 6288
GD H D+ + LQP +PC + C +C+
Sbjct: 3142 HKFRGDGCGTLINTIHRPMDIRVFHYYRQLQPEV----NPC--DTAGCQTLCV 3188
Score = 65.9 bits (159), Expect = 3e-08
Identities = 60/239 (25%), Positives = 86/239 (35%), Gaps = 7/239 (2%)
Frame = +1
Query: 10879 CTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQ-RICPVGEFQCTNHNCTR 11055
C++ QF C D KCIP LW CD DC DGSDE G C + C G F CT N
Sbjct: 3 CSQSQFTCVMD-GKCIPALWRCDTSADCSDGSDEVG---CDKAHACNEGMFHCTVSNRCI 58
Query: 11056 PFQIXXXXXXXXXXXXEQNCDKACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEADTL 11235
P + + D C A +C+P + + E D
Sbjct: 59 PHDWTCDGDVDCGLVEKYDMVDVSDEDPQLCRAHTKCLPTQ-----ALCSDGKCLEIDRF 113
Query: 11236 CMSAERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXETPECAQIECKKGWTRCSSSYR 11415
C A +C+ +E C++N T C ++C S R
Sbjct: 114 CDGA-WDCSNDELNCSSN-------------DTATASAPTSACDALKCSYDCRLTSEGAR 159
Query: 11416 CI------PNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMCDTEN 11574
C PN + C D+C+ D Q C + G ++C+ + + + C N
Sbjct: 160 CFCAKDSQPNGSVCEDFDECQIEGLCD-QMCK--NQPGAYQCSCTTGYVRQGNTCTAVN 215
Score = 65.1 bits (157), Expect = 5e-08
Identities = 58/198 (29%), Positives = 82/198 (41%), Gaps = 32/198 (16%)
Frame = +1
Query: 8404 DGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCT-NRRCIDSAKKCNHIDDCG 8580
DG CI CD+ DC+D SDE +C E CT + RCI C+ DCG
Sbjct: 13 DGKCIPALWRCDTSADCSDGSDE-VGCDKAHACNEGMFHCTVSNRCIPHDWTCDGDVDCG 71
Query: 8581 --------DGSDELD--CPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQV----SD 8718
D SDE C + C CS+G C+ + CDG DC ++++ +D
Sbjct: 72 LVEKYDMVDVSDEDPQLCRAHTKCLPTQALCSDGKCLEIDRFCDGAWDCSNDELNCSSND 131
Query: 8719 ESLATCP-------GLPIDCR----GVKVRCPNTNICIQP-ADLCDGYDDCG-----DKA 8847
+ A+ P DCR G + C + QP +C+ +D+C D+
Sbjct: 132 TATASAPTSACDALKCSYDCRLTSEGARCFCAKDS---QPNGSVCEDFDECQIEGLCDQM 188
Query: 8848 DENQLFCMNQQCAQHYVR 8901
+NQ C YVR
Sbjct: 189 CKNQPGAYQCSCTTGYVR 206
Score = 62.4 bits (150), Expect = 3e-07
Identities = 61/225 (27%), Positives = 96/225 (42%), Gaps = 16/225 (7%)
Frame = +1
Query: 12916 NQNTGFIFVCLPDGRYLKKIVAG--HLQQPTALITAPSAGRICYSDAGL-HAKIECADMD 13086
+Q IFVC P + IV + +P + P+ G + +S G IE + +D
Sbjct: 331 DQQREIIFVCSPQMVHCAIIVEALSEVLRPRRMALDPTKGFLFFSKWGSGDVSIERSLLD 390
Query: 13087 GTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSER------TTVVHD 13248
GT+R IV + + +P +A+D +YWVD V VN DGS R T + +
Sbjct: 391 GTNRTSIVLNKIITPLDIALDLVM-QHVYWVDTHLDTVQRVNYDGSGRWFPKRSTQFLFN 449
Query: 13249 RHIPYAVDVFENHIYWLSRESKTLY-VQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQ 13425
+ YA+DVFE IY S ++ ++ + G RV V + H V + + +
Sbjct: 450 FQMLYALDVFERTIYLASWQNGSIVALNGTTGEARVIVPNAP----HAVHLHVFHRQKQP 505
Query: 13426 RTVSGC--ERAQCSHLCVSL-PSTGFA---CLCPDGIVPQLDGSC 13542
C + C LC+ + G A C+C G + C
Sbjct: 506 EVAHPCRIQNGGCDQLCIPVWKKIGVAIAQCMCSPGYRLKTKSQC 550
Score = 54.7 bits (130), Expect = 7e-05
Identities = 44/184 (23%), Positives = 64/184 (33%), Gaps = 8/184 (4%)
Frame = +1
Query: 3169 NSTQFQC-KNGRCIPKEWKCDGENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKKCI 3345
+ +QF C +G+CIP W+CD DC D SDE+ C C E C + +CI
Sbjct: 4 SQSQFTCVMDGKCIPALWRCDTSADCSDGSDEVG-----CDKAHACNEGMFHCTVSNRCI 58
Query: 3346 PAQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXX 3525
P + DG +K+
Sbjct: 59 PHD------------------WTCDGDVDCGLVEKYD------------------MVDVS 82
Query: 3526 XEKLEMC-GNATCAANQFSCANGRCIPIYWLCDGDNDCYD------GTDEDKERCPPVQC 3684
E ++C + C Q C++G+C+ I CDG DC + D P C
Sbjct: 83 DEDPQLCRAHTKCLPTQALCSDGKCLEIDRFCDGAWDCSNDELNCSSNDTATASAPTSAC 142
Query: 3685 SALQ 3696
AL+
Sbjct: 143 DALK 146
Score = 52.8 bits (125), Expect = 2e-04
Identities = 69/317 (21%), Positives = 125/317 (38%), Gaps = 19/317 (5%)
Frame = +1
Query: 2350 DGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLI 2529
DG+ ++ VL +++ DW++++LY ++ R+++ V+ T L
Sbjct: 3804 DGKHSSVVLKDDEIHPIAIACDWLTERLYVINKKRSNIFVMSFNGTN--------HTTLT 3855
Query: 2530 TELRDPVSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAEN 2709
+ P+ +VV P G++ ++ I +DG+ Q + +T + S +AID
Sbjct: 3856 ATGKHPIDLVVDPVSGMMVWSIM---ETIISSGMDGRGKQKLVHTNVEWASGLAIDTTTK 3912
Query: 2710 RLCWGDTLLKTI-SCMDFDG--KNVVKLDIDNPIPVAITIMNEYIYYV--HQRPYSIRRV 2874
RL W D TI +C+ G ++V+ D P + + + +Y + +Q + +
Sbjct: 3913 RLYWADYRKSTIETCLLLTGGDRHVIAELHDYSKPKLLDVFEDSVYVILYNQNILKLNKY 3972
Query: 2875 HKKNG--------GGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQC--TQ 3024
+ NG G + +D I LK D S +PC S C +
Sbjct: 3973 GRDNGTYMNEEARGAGGLAGYRSSDVHFIHPLK---------HDRSVPNPCIISPCHNST 4023
Query: 3025 LCFATPSESHPNELEAKCAC---RQGFMINKENN-HSCQKDPAEKIEQLCSSNSTQFQCK 3192
+C S + L+ C C R + ++ C PA+ E + C
Sbjct: 4024 VCLL----STVSRLKRACVCPDARPRIVFDERGEVKECLDLPAQAPE-------CKLHCN 4072
Query: 3193 NGRCIPKEWKCDGENDC 3243
NG C DG+ C
Sbjct: 4073 NGTCF---IDTDGQQKC 4086
Score = 49.3 bits (116), Expect = 0.003
Identities = 41/196 (20%), Positives = 85/196 (42%), Gaps = 7/196 (3%)
Frame = +1
Query: 12964 LKKIVAGHLQQPTALITAPSAGRICYSDAGLHA-KIECADMDGTHRQIIVKDL---VFSP 13131
++ V L P +++ P G + +S + + +I+ A M+GT +++V + P
Sbjct: 669 MRYTVLRQLYAPKSIVVDPKQGWMYWSSWSVPSGRIDRAWMNGTQPELLVSSKERPIEWP 728
Query: 13132 TSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDR---HIPYAVDVFENHIYWLS 13302
T ++ID + R+YW D + ++++N+DGS R + R P A+ V +Y+
Sbjct: 729 TGLSIDMIQ-KRLYWCDARLSFIESINLDGSNRVLLFDGRSQNQFPVALAVHRQLLYFAD 787
Query: 13303 RESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLP 13482
+ + + + + +++ + + CE C +C++ P
Sbjct: 788 NVKGHIEKLNLSDPHLLETITIEKPQVLGLKIFDNLTQYGGNGRNACE-IDCPGICLNTP 846
Query: 13483 STGFACLCPDGIVPQL 13530
+C C DG V L
Sbjct: 847 VAVASCKCEDGQVLSL 862
Score = 40.0 bits (92), Expect = 1.7
Identities = 48/175 (27%), Positives = 69/175 (39%), Gaps = 2/175 (1%)
Frame = +1
Query: 8269 VQCSCNDTYELVQEPGKDYPTQCVLRGSNSEPAKECLPPYNFQCGDGSCILLGATCDSKP 8448
V C + Y++V +D P C +CLP C DG C+ + CD
Sbjct: 68 VDCGLVEKYDMVDVSDED-PQLC-------RAHTKCLPTQAL-CSDGKCLEIDRFCDGAW 118
Query: 8449 DCA-DASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHIDDCGDGSDELDCPSAVACA 8625
DC+ D + + N T S P + C A KC++ DC S+ C CA
Sbjct: 119 DCSNDELNCSSNDTATASAPT--SAC-------DALKCSY--DCRLTSEGARC----FCA 163
Query: 8626 EGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPG-LPIDCRGVKVRCPNT 8787
+ + P NG VC+ ++C E + D+ PG C VR NT
Sbjct: 164 KDSQP--NG------SVCEDFDECQIEGLCDQMCKNQPGAYQCSCTTGYVRQGNT 210
>gi|47229537|emb|CAG06733.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 2303
Score = 971 bits (2509), Expect = 0.0
Identities = 577/1697 (34%), Positives = 816/1697 (48%), Gaps = 140/1697 (8%)
Frame = +1
Query: 7693 TIASGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPA 7872
T++ D A +D C L+FW T+ P I R+ L G + VI+ I P
Sbjct: 71 TMSGEDHPRAFVLDECQSLMFW------TNWNEQSPSIMRATLTGSNVIVIIGSDIRTPN 124
Query: 7873 AIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGYRAK--SLDIWDRWLYMSDPLSN 8046
+A+D R +K+Y++D IE +YDG R V+ L ++ +++ +D +
Sbjct: 125 GLAIDHRAEKLYFSDATLDKIERCEYDGTRRYVVLKNEPVHPFGLAVYGDYIFWTDWVRR 184
Query: 8047 GVFRIDKESGSGLENVVSDRRIPGA-LRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQ 8223
V R +K +G ++ + +D IP + + A +D N+ +C+ +NGGC
Sbjct: 185 AVLRANKYTGGDMKLLRAD--IPQQPMGIVAVANDT-------NSCEFSMCRVNNGGCQD 235
Query: 8224 LCTVVADDIGLAASKVQCSCNDTYELVQEPG-KDYPTQ------------CVLRGSNSEP 8364
LC + ++ +V CSC +L+++ Y T L S+
Sbjct: 236 LCLLTSE------GRVNCSCRGDRKLLEDSTCSGYTTSFFFLLTWKCQTAAFLNASSCTA 289
Query: 8365 AKE-CLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCI 8541
C F+CG+G CI TCD C D SDE +YC R C + Y C N RC+
Sbjct: 290 LNTTCNVVDGFECGNGDCINYTLTCDGMAHCKDKSDEKQSYCANRVCKKGYRRCVNGRCV 349
Query: 8542 DSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDE 8721
CN DDCGD SDE+ C + + C F C +G CI+ + CD DC D DE
Sbjct: 350 GHGSWCNGRDDCGDNSDEIFCNTTL-CTADQFQCRDGSCISNSSKCDQKVDCED--AGDE 406
Query: 8722 SLATCPGLPIDCR-----GVK----VRCPNTNICIQPADLCDGYDDCGDKADE-NQLFCM 8871
T DC GVK +C T +C P+ LCDG +DCGD +DE N
Sbjct: 407 MNCTAT----DCSSYFHLGVKGVTFQKCEFTTLCYAPSWLCDGANDCGDFSDERNCPGSS 462
Query: 8872 NQQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNL 9051
++C + CPSGRCIP++W CD +NDC +G DE H + K C FQC N
Sbjct: 463 KEKCPTPFFACPSGRCIPKSWTCDKENDCENGADEAHCD-------KFCSATQ-FQCANN 514
Query: 9052 KCISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCD 9231
+CI + ++ S+ C +TC+ + F C + + CIP+ W CD
Sbjct: 515 RCIPQRWVCDGADDCGDSSDEDSQ--CKTKTCSPEAFQCPGS-------HMCIPQRWKCD 565
Query: 9232 GDVTCAGGEDESTELCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTY 9411
GD C G DES + C+ EF C N+ CI + CD DNDC DGSDE C Y
Sbjct: 566 GDKDCPDGTDESVKAGCVFNNTCSSNEFMCQNRQCIPKHFVCDHDNDCGDGSDESQECEY 625
Query: 9412 SSCQPDFFQCANHKC-VPNSWKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTS 9588
+C P F+CAN +C + +SW+CDG+ DC D SDE P N A+KC+N + C++
Sbjct: 626 PTCGPKEFRCANGRCLIQSSWECDGDFDCHDQSDE--APLNPRCGGPANKCNNTAYACSN 683
Query: 9589 GECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAI 9768
G C+++ +CDR DC D SDE + CFI+EC ++ C Q C D+KIG+KC C GF +
Sbjct: 684 GNCVNETLLCDRKDDCGDGSDELN-CFINECLNSKLSGCSQLCEDLKIGFKCRCHPGFRL 742
Query: 9769 DISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFF 9948
D+K+C +++EC C+Q+C + GS+ C CV+GY LS ++ + ++ + EPF
Sbjct: 743 K-DDRKTCIDIDECTTTYP-CTQRCINTHGSFHCLCVEGYHLSPENPTICKSTSDEEPFL 800
Query: 9949 LLANKHYIRKISIDGNKYEL---------------------------------AAQGFDN 10029
+ AN++Y+RK+++DG+ Y L QG +N
Sbjct: 801 IFANRYYLRKLNLDGSNYTLLKQVRLAFTLFSGVALKDTRRVCCGPRLTELHVLQQGLNN 860
Query: 10030 VVSLDIDLTEKKAYLID---QGKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDWV 10200
V+LD D ++ Y D QG + + M S + + R ++ +G+AVDWV
Sbjct: 861 AVALDFDYRQQMIYWTDVTTQGSM------IRRMYINGSDVQVLHRTSLSNPDGLAVDWV 914
Query: 10201 GRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFFTEWSLQPYIGR 10380
G LY ++ +I V +L+G + L+ +++P+A+ V GYL++++W P+IGR
Sbjct: 915 GGNLYWCDKGRDTIEVSKLNGAYRTVLVNSGLREPRAVAVDVRYGYLYWSDWGDNPHIGR 974
Query: 10381 IALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHIP 10560
I +DG+ + E + WPN + +D+ +DR++W DA + I F DG RRH
Sbjct: 975 IGMDGTNR-----SIIIEEKITWPNGLTLDFVNDRIYWADAREDYIAFASLDGT-RRHTS 1028
Query: 10561 AQRT--------------------------------SHVSSMVVFDDYLYWADWNLREVL 10644
T H+ +M +F++Y+YW DW + +
Sbjct: 1029 KTHTHTHTFELKNDRYSNVAPDCCLWVRCTVLVKDIPHIFAMSLFEEYIYWTDWETKSIN 1088
Query: 10645 RCDKWTGKNETILKKTVQLPNDLRIVHPMRQPAYPN-PCGDNNGGCSHLCLIGAGGNGYT 10821
R K G N+T+L T+ P D+ I HP RQP N PC NNGGCS+LCLI GG GY
Sbjct: 1089 RAHKTLGTNKTVLISTLHRPMDIHIYHPYRQPEVENHPCQMNNGGCSNLCLISPGG-GYQ 1147
Query: 10822 CSCPDQFVLLSDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICG 11001
C+CP F L +D K C NCT QF C D KCIP W CD E DC D SDEP + C
Sbjct: 1148 CACPTNFYLAADGKQCLSNCTASQFVCKND--KCIPFWWKCDTEDDCGDRSDEPAD--CP 1203
Query: 11002 QRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXXEQNCD-KACDPWMFKCAATGRCIPRR 11178
+ C G+FQC CT P I E NCD C P FKC + RCIP
Sbjct: 1204 EFKCRPGQFQCGTGICTNPAYICDGDNDCHDNSDEANCDIHVCLPSQFKCTSPSRCIPGI 1263
Query: 11179 FTXXXXXXXXXRSDEADTLCMSAERNCTAEEFRCN-NNKCIAKAWRXXXXXXXXXXXXET 11355
F DE D E C +F+C +CI + W E
Sbjct: 1264 FRCNSQDNCGEGEDEKD----CPEVTCAPNQFQCAITKRCIPRVWVCDRDNDCVDGSDEP 1319
Query: 11356 PECAQIECKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCP--TCDDVGEFRCAT 11529
C Q+ C RC S RCIP C+G+DDC D SDE K+ C TC+ +FRC
Sbjct: 1320 ANCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDASDEPKEECDERTCEPY-QFRC-K 1377
Query: 11530 SGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQC 11709
+ +C+P RW CD +NDCGDNSDE C R CSESEF C +G+CI G CDG C
Sbjct: 1378 NNRCVPGRWQCDYDNDCGDNSDE--DKC--VPRQCSESEFACTNGRCIAGRWKCDGDHDC 1433
Query: 11710 SDGLDESQCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFE 11889
+DG DE+ C + +C QC + CI CD DC + +DE C+ R C E
Sbjct: 1434 ADGSDENGCEV-KCDSDQYQCKNSHCIPLRWHCDADPDCLDGSDEEKCDSGVVRHCPKDE 1492
Query: 11890 FECANSVCIPRKFMXXXXXXXXXXSDETSSEC---------RSA---------------- 11994
F+C N++C P+ + SDE EC R A
Sbjct: 1493 FQCNNTLCKPQGWKCDGEDDCGDNSDENPEECGEDFYGSAFRQAVLFHRYVLIHSELLVC 1552
Query: 11995 -----QCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSFSEYGDCSSDQ 12159
QC P +FRC + R+CL + + C+G N+CG N SDE C C +
Sbjct: 1553 LSVIFQCPPTRQFRCLNDRVCLPLSKRCDGVNNCGDN--SDE--LDCQVPPPIPVCQKHE 1608
Query: 12160 FKCANGKCVNGTVACDRKDDCGD-ASDEIGCSK--------HGGKTSCEAFGNNGGCKHI 12312
F+C+NG+C++ C+ +DC D SDEI C+K +T C +G H
Sbjct: 1609 FQCSNGRCISSIFRCNYFNDCEDYGSDEINCNKKDTALNDCRSNRTVC----GDGDEAHC 1664
Query: 12313 CTDVRDGFYCHCRDGFR 12363
+ D F C CR GF+
Sbjct: 1665 VVNGTDSF-CSCRPGFQ 1680
Score = 428 bits (1100), Expect = e-117
Identities = 353/1237 (28%), Positives = 510/1237 (40%), Gaps = 120/1237 (9%)
Frame = +1
Query: 10303 PKAIVVHPGKGYLFFTEWSLQ-PYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFS 10479
P+A V+ + +F+T W+ Q P I R L GS + + D+ PN +AID+ +
Sbjct: 78 PRAFVLDECQSLMFWTNWNEQSPSIMRATLTGSN-----VIVIIGSDIRTPNGLAIDHRA 132
Query: 10480 DRLFWGDAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKW 10659
++L++ DA L++I ++DG R + H + V+ DY++W DW R VLR +K+
Sbjct: 133 EKLYFSDATLDKIERCEYDGTRRYVVLKNEPVHPFGLAVYGDYIFWTDWVRRAVLRANKY 192
Query: 10660 TGKNETILKKTV-QLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPD 10836
TG + +L+ + Q P + V + C NNGGC LCL+ + G CSC
Sbjct: 193 TGGDMKLLRADIPQQPMGIVAVANDTNSCEFSMCRVNNGGCQDLCLLTSEGR-VNCSCRG 251
Query: 10837 QFVLLSDQKTCE----------------------PNCTERQ--------FACGGDDAKCI 10926
LL D TC +CT F CG D CI
Sbjct: 252 DRKLLED-STCSGYTTSFFFLLTWKCQTAAFLNASSCTALNTTCNVVDGFECGNGD--CI 308
Query: 10927 PKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXXE 11106
CDG C+D SDE +S C R+C G +C N
Sbjct: 309 NYTLTCDGMAHCKDKSDEK-QSYCANRVCKKGYRRCVN---------------------- 345
Query: 11107 QNCDKACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEADTLCMSAERNCTAEEFRCNN 11286
GRC+ SDE C + CTA++F+C +
Sbjct: 346 -----------------GRCVGHGSWCNGRDDCGDNSDE--IFCNTT--LCTADQFQCRD 384
Query: 11287 NKCIAKAWRXXXXXXXXXXXXETPECAQIECK-------KGWT--RCSSSYRC-IPNWAF 11436
CI+ + + E C +C KG T +C + C P+W
Sbjct: 385 GSCISNSSKCDQKVDCEDAGDEM-NCTATDCSSYFHLGVKGVTFQKCEFTTLCYAPSW-L 442
Query: 11437 CNGQDDCRDNSDE------DKQRCPTCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDE 11598
C+G +DC D SDE K++CPT F SG+CIP+ W CD ENDC + +DE
Sbjct: 443 CDGANDCGDFSDERNCPGSSKEKCPT-----PFFACPSGRCIPKSWTCDKENDCENGADE 497
Query: 11599 LDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDE-SQCTLRRCLPGHRQCD 11775
A C + CS ++F+C + +CIP VCDG C D DE SQC + C P QC
Sbjct: 498 --AHC---DKFCSATQFQCANNRCIPQRWVCDGADDCGDSSDEDSQCKTKTCSPEAFQCP 552
Query: 11776 DG-TCIAEHKWCDRKKDCPNAADE-LHCEDVSRRTCSPFEFECANSVCIPRKFMXXXXXX 11949
CI + CD KDCP+ DE + V TCS EF C N CIP+ F+
Sbjct: 553 GSHMCIPQRWKCDGDKDCPDGTDESVKAGCVFNNTCSSNEFMCQNRQCIPKHFVCDHDND 612
Query: 11950 XXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSF 12129
SDE S EC C P FRCA+ R + C+G DC +D SDE
Sbjct: 613 CGDGSDE-SQECEYPTCGPK-EFRCANGRCLIQSSWECDGDFDC--HDQSDEAPLNPRCG 668
Query: 12130 SEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKH 12309
C++ + C+NG CVN T+ CDRKDDCGD SDE+ C + S GC
Sbjct: 669 GPANKCNNTAYACSNGNCVNETLLCDRKDDCGDGSDELNCFINECLNS-----KLSGCSQ 723
Query: 12310 ICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGSYLCRCHEDY-- 12483
+C D++ GF C C GFR K CIDIDEC CTQ C+NT GS+ C C E Y
Sbjct: 724 LCEDLKIGFKCRCHPGFRL-KDDRKTCIDIDECTTTYPCTQRCINTHGSFHCLCVEGYHL 782
Query: 12484 --ENNVVVGSMTGKDCRAKGDAANVMIGADD-SLVQLSLHGS------------------ 12600
EN + C++ D +I A+ L +L+L GS
Sbjct: 783 SPENPTI--------CKSTSDEEPFLIFANRYYLRKLNLDGSNYTLLKQVRLAFTLFSGV 834
Query: 12601 ----------GTNRHXXXXXXXXXXXXXXXXXXPRKELMYWID-GSERTIYRSAIANGNQ 12747
G R++++YW D ++ ++ R NG+
Sbjct: 835 ALKDTRRVCCGPRLTELHVLQQGLNNAVALDFDYRQQMIYWTDVTTQGSMIRRMYINGSD 894
Query: 12748 SHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNT 12927
+ + P +AVD+ GNL+ + G T ++
Sbjct: 895 VQVLHRTSLS------NPDGLAVDWVGGNLYWC------DKGRDTIEVSKL--------- 933
Query: 12928 GFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQII 13107
+G Y +V L++P A+ G + +SD G + I MDGT+R II
Sbjct: 934 --------NGAYRTVLVNSGLREPRAVAVDVRYGYLYWSDWGDNPHIGRIGMDGTNRSII 985
Query: 13108 VKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTT-----------VVHDRH 13254
+++ + P + +D +RIYW D + + ++DG+ R T + +DR+
Sbjct: 986 IEEKITWPNGLTLD-FVNDRIYWADAREDYIAFASLDGTRRHTSKTHTHTHTFELKNDRY 1044
Query: 13255 -------------------IP--YAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASD 13371
IP +A+ +FE +IYW E+K++ K +VL S
Sbjct: 1045 SNVAPDCCLWVRCTVLVKDIPHIFAMSLFEEYIYWTDWETKSINRAHKTLGTNKTVLIST 1104
Query: 13372 LEDGHTVRVSQKYAK-DTQRTVSGCERAQCSHLCVSLPSTGFACLCPDGIVPQLDG-SCA 13545
L + + Y + + + CS+LC+ P G+ C CP DG C
Sbjct: 1105 LHRPMDIHIYHPYRQPEVENHPCQMNNGGCSNLCLISPGGGYQCACPTNFYLAADGKQCL 1164
Query: 13546 TQHVEALTMPKQCKCTN-GGKCRLDGSCECTSDFEGD 13653
+ + + K KC KC + C SD D
Sbjct: 1165 SNCTASQFVCKNDKCIPFWWKCDTEDDCGDRSDEPAD 1201
Score = 395 bits (1016), Expect = e-107
Identities = 343/1271 (26%), Positives = 501/1271 (38%), Gaps = 103/1271 (8%)
Frame = +1
Query: 7423 ISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAENPRLVFGASKQPHAKEIRHISDM 7602
++N D D + +Y+ + G I +N ++ L H + + +
Sbjct: 858 LNNAVALDFDYRQQMIYWTDVTTQGSMIRRMYINGSDVQVL--------HRTSLSNPDGL 909
Query: 7603 KLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTIASGDWTY--ALAIDPCSGLLFWSDSGYK 7776
+DW+ +Y+ + G + + + + A+A+D G L+WSD G
Sbjct: 910 AVDWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVNSGLREPRAVAVDVRYGYLYWSDWGDN 969
Query: 7777 TSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVDFRNQKIYWADVNRLNIEVADYDG 7956
P I R + G +R +I+ E I+ P + +DF N +IYWAD I A DG
Sbjct: 970 -------PHIGRIGMDGTNRSIIIEEKITWPNGLTLDFVNDRIYWADAREDYIAFASLDG 1022
Query: 7957 QNRKVIASGYRAKSLDI---------------------------------WDRWLYMSDP 8037
R + + ++ ++ ++Y +D
Sbjct: 1023 TRRHTSKTHTHTHTFELKNDRYSNVAPDCCLWVRCTVLVKDIPHIFAMSLFEEYIYWTDW 1082
Query: 8038 LSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGC 8217
+ + R K G+ ++S P + ++ N C + +NGGC
Sbjct: 1083 ETKSINRAHKTLGTNKTVLISTLHRPMDIHIYHPYRQPEVENHPC--------QMNNGGC 1134
Query: 8218 DQLCTV---------VADDIGLAASKVQCSCNDTY-ELVQEPGKDYPT--QCVLR---GS 8352
LC + + LAA QC N T + V + K P +C G
Sbjct: 1135 SNLCLISPGGGYQCACPTNFYLAADGKQCLSNCTASQFVCKNDKCIPFWWKCDTEDDCGD 1194
Query: 8353 NSEPAKEC----LPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSC-PEDYN 8517
S+ +C P FQCG G C CD DC D SDE C+ C P +
Sbjct: 1195 RSDEPADCPEFKCRPGQFQCGTGICTNPAYICDGDNDCHDNSDEAN--CDIHVCLPSQFK 1252
Query: 8518 LCTNRRCIDSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCS-NGHCINQTKVCDGHND 8694
+ RCI +CN D+CG+G DE DCP V CA F C+ CI + VCD ND
Sbjct: 1253 CTSPSRCIPGIFRCNSQDNCGEGEDEKDCPE-VTCAPNQFQCAITKRCIPRVWVCDRDND 1311
Query: 8695 CHDEQVSDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMN 8874
C D SDE A C + C + RC ++ CI CDG DDCGD +DE + C
Sbjct: 1312 CVDG--SDEP-ANCTQMT--CGVDEFRCKDSGRCIPARWKCDGEDDCGDASDEPKEECDE 1366
Query: 8875 QQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLK 9054
+ C + RC + RC+P WQCD DNDC D DE K
Sbjct: 1367 RTCEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDED------------------------K 1402
Query: 9055 CISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDG 9234
C+ R C++ EF CT+ CI W CDG
Sbjct: 1403 CVPRQ-------------------------CSESEFACTNG--------RCIAGRWKCDG 1429
Query: 9235 DVTCAGGEDESTELCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHA--NCT 9408
D CA G DE+ C+ + C+ +++C N HCI W CD D DCLDGSDE +
Sbjct: 1430 DHDCADGSDENG--CEVK---CDSDQYQCKNSHCIPLRWHCDADPDCLDGSDEEKCDSGV 1484
Query: 9409 YSSCQPDFFQCANHKCVPNSWKCDGNDDCEDGSDE--KDCPKN---SASAQ--------- 9546
C D FQC N C P WKCDG DDC D SDE ++C ++ SA Q
Sbjct: 1485 VRHCPKDEFQCNNTLCKPQGWKCDGEDDCGDNSDENPEECGEDFYGSAFRQAVLFHRYVL 1544
Query: 9547 ---KASKCSNGQFQCTSGE---CIDD------AKVCDRNFDCTDRSDESSLCF---IDEC 9681
+ C + FQC C++D +K CD +C D SDE I C
Sbjct: 1545 IHSELLVCLSVIFQCPPTRQFRCLNDRVCLPLSKRCDGVNNCGDNSDELDCQVPPPIPVC 1604
Query: 9682 SLAEKPLCEQKCMD--MKIGYKCDCFEGFAIDISDQKSCHNVNECYEGISGCSQ----KC 9843
E +C+ + Y DC + + +I+ K +N+C + C C
Sbjct: 1605 QKHEFQCSNGRCISSIFRCNYFNDCEDYGSDEINCNKKDTALNDCRSNRTVCGDGDEAHC 1664
Query: 9844 DDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYELAAQGF 10023
C C G+Q + R E L + K + D + L +Q
Sbjct: 1665 VVNGTDSFCSCRPGFQTNG------RNRCEGAVVSALLWRRLEVKAARDPGR--LISQIR 1716
Query: 10024 DNVVSLDI---------DLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNVYGT 10176
+V SL+ D T A I R + ++ P
Sbjct: 1717 TSVCSLESAPTCATTPKDPTSAAATNISPKSTTPARPMIPDLKMP--------------- 1761
Query: 10177 EGIAVDWVGRKLYMLNRQERSIRVCELDG-RFCKTLIRDRIQQPKAIVVHPGKGYLFFTE 10353
GIAVDWV LY + I V ++ KTLI I +P AIVV P +G +++ +
Sbjct: 1762 RGIAVDWVAGNLYWTDSGRDVIEVAQISKTHHRKTLISGMIDEPYAIVVDPQRGRMYWAD 1821
Query: 10354 WSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDF 10533
W P I A+DG+ L E ++ WP +A+DYF++RL+W DA L+ I +
Sbjct: 1822 WGNHPKIETAAMDGTMRET-----LVEKNIQWPTGLAVDYFNERLYWADAKLSLICSVRL 1876
Query: 10534 DGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDL 10713
+G+ S+ VF+DY+Y + V R +K+ L + D+
Sbjct: 1877 NGSD------AVLRQPFSIDVFEDYVYGVTYINNYVFRVNKFGKGPIENLTTGMNHATDI 1930
Query: 10714 RIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTCEPNCTERQ 10893
+ H +QP NPC C LCL+ +G C+CP+ +L + TC T
Sbjct: 1931 VLYHRYKQPEVNNPCDSKK--CEWLCLLSP--SGPVCTCPNGHML--NNGTCVETPTPTL 1984
Query: 10894 FACGGDDAKCI 10926
G C+
Sbjct: 1985 SPIGPPSGPCL 1995
Score = 380 bits (976), Expect = e-103
Identities = 305/1116 (27%), Positives = 462/1116 (41%), Gaps = 176/1116 (15%)
Frame = +1
Query: 2545 PVSVVVHPWKGLLFYAEAMRPA-AIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCW 2721
P + V+ + L+F+ + +I R + G N VI + + P+ +AID +L +
Sbjct: 78 PRAFVLDECQSLMFWTNWNEQSPSIMRATLTGSNVIVIIGSDIRTPNGLAIDHRAEKLYF 137
Query: 2722 GDTLLKTISCMDFDGKNVVKLDIDNPI-PVAITIMNEYIYYVHQRPYSIRRVHKKNGGGS 2898
D L I ++DG + + P+ P + + +YI++ ++ R +K GG
Sbjct: 138 SDATLDKIERCEYDGTRRYVVLKNEPVHPFGLAVYGDYIFWTDWVRRAVLRANKYTGGDM 197
Query: 2899 KIVREFGAD-ERSIFSLKACSHQNQPIPDDSREHPCRASQ--CTQLCFATPSESHPNELE 3069
K++R AD + + A ++ + CR + C LC T +E
Sbjct: 198 KLLR---ADIPQQPMGIVAVANDT----NSCEFSMCRVNNGGCQDLCLLT------SEGR 244
Query: 3070 AKCACRQGFMINKENNHS-------------CQKDPAEKIEQLCSSNST-----QFQCKN 3195
C+CR + +++ S CQ + N+T F+C N
Sbjct: 245 VNCSCRGDRKLLEDSTCSGYTTSFFFLLTWKCQTAAFLNASSCTALNTTCNVVDGFECGN 304
Query: 3196 GRCIPKEWKCDGENDCLDESDE--------IDEKGDK-------------CFHETECAEN 3312
G CI CDG C D+SDE + +KG + C +C +N
Sbjct: 305 GDCINYTLTCDGMAHCKDKSDEKQSYCANRVCKKGYRRCVNGRCVGHGSWCNGRDDCGDN 364
Query: 3313 T--IKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKY-CKD-GQKPVCAAKKFQCDNHR--- 3471
+ I C NT C Q K C+D G + C A H
Sbjct: 365 SDEIFC-NTTLCTADQFQCRDGSCISNSSKCDQKVDCEDAGDEMNCTATDCSSYFHLGVK 423
Query: 3472 ------------CIPEQWKXXXXXXXXXXXXEKLEMCGNAT---CAANQFSCANGRCIPI 3606
C W E+ C ++ C F+C +GRCIP
Sbjct: 424 GVTFQKCEFTTLCYAPSWLCDGANDCGDFSDER--NCPGSSKEKCPTPFFACPSGRCIPK 481
Query: 3607 YWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQCVPLRNHXXXXXXXXXXXXXXX 3786
W CD +NDC +G DE C CSA QF+CAN R C+P R
Sbjct: 482 SWTCDKENDCENGADE--AHCDKF-CSATQFQCANNR-CIPQRWVCDGADDCGDSSDEDS 537
Query: 3787 XAVTAESCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEP-KFGCTSGRQCSSDQFKCG 3963
T ++C+P+ F+C S +CIP WK +DE K GC CSS++F C
Sbjct: 538 QCKT-KTCSPEAFQCPGSHMCIPQRWKCDGDKDCPDGTDESVKAGCVFNNTCSSNEFMCQ 596
Query: 3964 NGRCILNNWLCDGENDCGDGSDESSE---------------------------------- 4041
N +CI +++CD +NDCGDGSDES E
Sbjct: 597 NRQCIPKHFVCDHDNDCGDGSDESQECEYPTCGPKEFRCANGRCLIQSSWECDGDFDCHD 656
Query: 4042 RGCKTSMNAR------KCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGGRCARDLC 4203
+ + +N R KC AC N C+ LCD K C G+DE +
Sbjct: 657 QSDEAPLNPRCGGPANKCNNTAYACSNGN--CVNETLLCDRKDDCGDGSDELNCFINECL 714
Query: 4204 SADRAGCSFKCHNSPNGPICSCPFGEQLVNKTK-CEPENECLDSSSCSQRCKDEKHGFTC 4380
++ +GCS C + G C C G +L + K C +EC + C+QRC + F C
Sbjct: 715 NSKLSGCSQLCEDLKIGFKCRCHPGFRLKDDRKTCIDIDECTTTYPCTQRCINTHGSFHC 774
Query: 4381 SCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDN----------------- 4509
C EGY L + T + + D ++ NR Y LD
Sbjct: 775 LCVEGYHLSPENPT--ICKSTSDEEPFLIFANRYYLRKLNLDGSNYTLLKQVRLAFTLFS 832
Query: 4510 ------------------WHTFGAIVENAIALAWDSLTDRIYWSDIREKKILSANR--NG 4629
H + NA+AL +D IYW+D+ + + NG
Sbjct: 833 GVALKDTRRVCCGPRLTELHVLQQGLNNAVALDFDYRQQMIYWTDVTTQGSMIRRMYING 892
Query: 4630 TNATVFIADGLDITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRG 4809
++ V L +G+A+DWVG NLYW D +TIEV+ L RT+LV+ + +PR
Sbjct: 893 SDVQVLHRTSLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLNGA-YRTVLVNSGLREPRA 951
Query: 4810 IAVDPRKGVMFWTDWGQNPCIERASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSK 4989
+AVD R G ++W+DWG NP I R MDGT+R II++ KI WPN + LD+ DR+Y+AD++
Sbjct: 952 VAVDVRYGYLYWSDWGDNPHIGRIGMDGTNRSIIIEEKITWPNGLTLDFVNDRIYWADAR 1011
Query: 4990 LDFIDFVNYDGSGR----------TQVLASSKF-------------------VQHPHALA 5082
D+I F + DG+ R T L + ++ + H A++
Sbjct: 1012 EDYIAFASLDGTRRHTSKTHTHTHTFELKNDRYSNVAPDCCLWVRCTVLVKDIPHIFAMS 1071
Query: 5083 IFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTN 5262
+FE+ +Y++D + + K GT T + + + HP QP ++N+PC N
Sbjct: 1072 LFEEYIYWTDWETKSINRAHK-TLGTNKTVLISTLHRPMDIHIYHPYRQPEVENHPCQMN 1130
Query: 5263 --PCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDD 5364
CS+LCL++ + C CP L A GK+C+ +
Sbjct: 1131 NGGCSNLCLISPGGGYQCACPTNFYLAADGKQCLSN 1166
Score = 364 bits (934), Expect = 4e-98
Identities = 323/1191 (27%), Positives = 456/1191 (38%), Gaps = 190/1191 (15%)
Frame = +1
Query: 2377 VTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITE-LRDPVS 2553
+++ DGL + DW+ LY+ D R+++EV K+ R L+ LR+P +
Sbjct: 903 LSNPDGL---AVDWVGGNLYWCDKGRDTIEVSKLNGA--------YRTVLVNSGLREPRA 951
Query: 2554 VVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTL 2733
V V G L++++ I R +DG N +I + P+ + +DF +R+ W D
Sbjct: 952 VAVDVRYGYLYWSDWGDNPHIGRIGMDGTNRSIIIEEKITWPNGLTLDFVNDRIYWADAR 1011
Query: 2734 LKTISCMDFDG----------------------KNVVK----------LDIDNPIPVAIT 2817
I+ DG NV L D P A++
Sbjct: 1012 EDYIAFASLDGTRRHTSKTHTHTHTFELKNDRYSNVAPDCCLWVRCTVLVKDIPHIFAMS 1071
Query: 2818 IMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSRE- 2994
+ EYIY+ SI R HK G ++ S H P E
Sbjct: 1072 LFEEYIYWTDWETKSINRAHKTLGTNKTVLI-------STLHRPMDIHIYHPYRQPEVEN 1124
Query: 2995 HPCRASQ--CTQLCFATPSESHPNELEAKCACRQGFMINKENNHSCQKDPAEKIEQLCSS 3168
HPC+ + C+ LC +P + +CAC F + + C S
Sbjct: 1125 HPCQMNNGGCSNLCLISPGGGY------QCACPTNFYLAADGKQ-------------CLS 1165
Query: 3169 NST--QFQCKNGRCIPKEWKCD-------------------------------------- 3228
N T QF CKN +CIP WKCD
Sbjct: 1166 NCTASQFVCKNDKCIPFWWKCDTEDDCGDRSDEPADCPEFKCRPGQFQCGTGICTNPAYI 1225
Query: 3229 --GENDCLDESDEID--------------------------EKGDKCFH--------ETE 3300
G+NDC D SDE + D C E
Sbjct: 1226 CDGDNDCHDNSDEANCDIHVCLPSQFKCTSPSRCIPGIFRCNSQDNCGEGEDEKDCPEVT 1285
Query: 3301 CAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQ-------KPVCAAKKFQC 3459
CA N +C TK+CIP C DG + C +F+C
Sbjct: 1286 CAPNQFQCAITKRCIPRVWVCDRDND-----------CVDGSDEPANCTQMTCGVDEFRC 1334
Query: 3460 -DNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNATCAANQFSCANGRCIPIYWLCDGDNDC 3636
D+ RCIP +WK E E C TC QF C N RC+P W CD DNDC
Sbjct: 1335 KDSGRCIPARWKCDGEDDCGDASDEPKEECDERTCEPYQFRCKNNRCVPGRWQCDYDNDC 1394
Query: 3637 YDGTDEDKERCPPVQCSALQFRCANGRQCVPLRNHXXXXXXXXXXXXXXXXAVTAESCTP 3816
D +DEDK C P QCS +F C NGR C+ R V C
Sbjct: 1395 GDNSDEDK--CVPRQCSESEFACTNGR-CIAGRWKCDGDHDCADGSDENGCEV---KCDS 1448
Query: 3817 DQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSG--RQCSSDQFKCGNGRCILNNW 3990
DQ++C +S CIP W SDE K C SG R C D+F+C N C W
Sbjct: 1449 DQYQCKNSH-CIPLRWHCDADPDCLDGSDEEK--CDSGVVRHCPKDEFQCNNTLCKPQGW 1505
Query: 3991 LCDGENDCGDGSDESSERGCKTSMNAR-------------------------KC-PFEHV 4092
CDGE+DCGD SDE+ E + + +C P
Sbjct: 1506 KCDGEDDCGDNSDENPEECGEDFYGSAFRQAVLFHRYVLIHSELLVCLSVIFQCPPTRQF 1565
Query: 4093 ACENDQETCIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCSFKCHNSPNGPIC--- 4263
C ND+ C+PL + CDG +C +DE C P P+C
Sbjct: 1566 RCLNDR-VCLPLSKRCDGVNNCGDNSDE-----------------LDCQVPPPIPVCQKH 1607
Query: 4264 --SCPFGEQLVNKTKCEPENECLDSSSCSQRCK-------------------DEKHGFT- 4377
C G + + +C N+C D S C DE H
Sbjct: 1608 EFQCSNGRCISSIFRCNYFNDCEDYGSDEINCNKKDTALNDCRSNRTVCGDGDEAHCVVN 1667
Query: 4378 -----CSCDEGYELDVDKRTCKVAD---------NVKDTRIYVSNRNRIYYSDHKLDNWH 4515
CSC G++ + + C+ A VK R ++I S L++
Sbjct: 1668 GTDSFCSCRPGFQTN-GRNRCEGAVVSALLWRRLEVKAARDPGRLISQIRTSVCSLESAP 1726
Query: 4516 TFGAIVENAIALAWDSLTDRIYWSDIREKKILSANRNGTNATVFIADGLDITEGIALDWV 4695
T ++ + A +++ ++ T A I D L + GIA+DWV
Sbjct: 1727 TCATTPKDPTSAAATNISP----------------KSTTPARPMIPD-LKMPRGIAVDWV 1769
Query: 4696 GRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQNPCIE 4875
NLYW DS + IEVA + R L+ + +P I VDP++G M+W DWG +P IE
Sbjct: 1770 AGNLYWTDSGRDVIEVAQISKTHHRKTLISGMIDEPYAIVVDPQRGRMYWADWGNHPKIE 1829
Query: 4876 RASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSK 5055
A+MDGT R+ +V+ I WP +A+DY +R+Y+AD+KL I V +G S
Sbjct: 1830 TAAMDGTMRETLVEKNIQWPTGLAVDYFNERLYWADAKLSLICSVRLNG--------SDA 1881
Query: 5056 FVQHPHALAIFEDMMY---YSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVL 5226
++ P ++ +FED +Y Y + + ++ + K P + +H A +V H
Sbjct: 1882 VLRQPFSIDVFEDYVYGVTYINNYVFRVNKFGKGPIENLTTGMNH----ATDIVLYHRYK 1937
Query: 5227 QPVIKNNPCSTNPCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKPFL 5379
QP + NNPC + C LCLL+ C CP G L + C++ P L
Sbjct: 1938 QPEV-NNPCDSKKCEWLCLLSPSGP-VCTCPNGHML--NNGTCVETPTPTL 1984
Score = 299 bits (765), Expect = 2e-78
Identities = 232/832 (27%), Positives = 332/832 (39%), Gaps = 167/832 (20%)
Frame = +1
Query: 148 SSVCNENDFRCNDGKCI--------RTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDT 303
+++C + F+C DG CI + + H G K +Q
Sbjct: 372 TTLCTADQFQCRDGSCISNSSKCDQKVDCEDAGDEMNCTATDCSSYFHLGVKGVTFQKCE 431
Query: 304 YTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGR----------- 450
+T C A CD DC D SDE++CP S+ + F C GR
Sbjct: 432 FT---TLCYAPSWLCDGANDCGDFSDERNCPGSSKEKCPTPFFACPSGRCIPKSWTCDKE 488
Query: 451 --------------------------QCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQ 552
+C CDG DC D SDE C C
Sbjct: 489 NDCENGADEAHCDKFCSATQFQCANNRCIPQRWVCDGADDCGDSSDEDSQCKTK--TCSP 546
Query: 553 YQFRCADKTQCIQKSWVCDGSKDCADGSDE--PDTCEFKK-CTANEFQCKNKRCQPRKFR 723
F+C CI + W CDG KDC DG+DE C F C++NEF C+N++C P+ F
Sbjct: 547 EAFQCPGSHMCIPQRWKCDGDKDCPDGTDESVKAGCVFNNTCSSNEFMCQNRQCIPKHFV 606
Query: 724 CDYYDDCGDNSDEDE------CG--EYRCPPGK------WNCPG---------------- 813
CD+ +DCGD SDE + CG E+RC G+ W C G
Sbjct: 607 CDHDNDCGDGSDESQECEYPTCGPKEFRCANGRCLIQSSWECDGDFDCHDQSDEAPLNPR 666
Query: 814 ----------------TGHCIDQLKLCDGSKDCADGADEQQCSQNLCPS---LGCQAGCH 936
G+C+++ LCD DC DG+DE C N C + GC C
Sbjct: 667 CGGPANKCNNTAYACSNGNCVNETLLCDRKDDCGDGSDELNCFINECLNSKLSGCSQLCE 726
Query: 937 PSPHGGECTCPSGYKL-DDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQ 1113
G +C C G++L DDR +TC DI+EC C Q C N F C C+ + + L
Sbjct: 727 DLKIGFKCRCHPGFRLKDDR--KTCIDIDECTTTYPCTQRCINTHGSFHCLCV-EGYHLS 783
Query: 1114 MEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKK-------LASGE 1272
E N T+ C S + ++ L A R L +LN + + K L SG
Sbjct: 784 PE------NPTI---CKSTSDEEPFLIFANRYYLRKLNLDGSNYTLLKQVRLAFTLFSGV 834
Query: 1273 FI-------------------------YGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEI 1377
+ +DFDY + I+WTD + + G
Sbjct: 835 ALKDTRRVCCGPRLTELHVLQQGLNNAVALDFDYRQQMIYWTDVTTQGSMIRRMYING-- 892
Query: 1378 SQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDI 1557
S ++ L SL P LAVDW+ LY + G I+VS +G RTVL+ GL P +
Sbjct: 893 SDVQVLHRTSLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVNSGLREPRAV 952
Query: 1558 ALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKV 1728
A+D G ++++ + + MDGTNR ++ +G+ +D R+YW D +
Sbjct: 953 AVDVRYGYLYWSDWGDNPHIGRIGMDGTNRSIIIEEKITWPNGLTLDFVNDRIYWADARE 1012
Query: 1729 DRLESIDYQGNDRRIVAQGMNV-----------------------------VPHPFGLAL 1821
D + G R + +PH F ++L
Sbjct: 1013 DYIAFASLDGTRRHTSKTHTHTHTFELKNDRYSNVAPDCCLWVRCTVLVKDIPHIFAMSL 1072
Query: 1822 FDQYLYWTDWTRLGVIQVEK-FGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLA 1998
F++Y+YWTDW + + K G++ +L S PM I YHP QP
Sbjct: 1073 FEEYIYWTDWETKSINRAHKTLGTNKTVLISTLHR---PMDIHIYHPYRQP--------- 1120
Query: 1999 MKIEN-PC--TNADCEGMCILSKDNGGFGVGYKCACPIGQKL-VNGKRCIDS 2142
++EN PC N C +C++S G GY+CACP L +GK+C+ +
Sbjct: 1121 -EVENHPCQMNNGGCSNLCLISP-----GGGYQCACPTNFYLAADGKQCLSN 1166
Score = 256 bits (655), Expect = 9e-66
Identities = 212/727 (29%), Positives = 311/727 (42%), Gaps = 59/727 (8%)
Frame = +1
Query: 139 NTASSVCNENDFRCND-GKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWH 315
N C ++FRC D G+CI W P + D+ C+ Y +
Sbjct: 1321 NCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDASD-----EPKEECDERTCEPYQFR 1375
Query: 316 SVS--CIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKY 489
+ C+ +CD DC D SDE C S++ F C +GR C KCDG +
Sbjct: 1376 CKNNRCVPGRWQCDYDNDCGDNSDEDKCVPRQC---SESEFACTNGR-CIAGRWKCDGDH 1431
Query: 490 DCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEP--DTCEFK 663
DC D SDE + C C Q++C + + CI W CD DC DGSDE D+ +
Sbjct: 1432 DCADGSDE-NGCE---VKCDSDQYQCKN-SHCIPLRWHCDADPDCLDGSDEEKCDSGVVR 1486
Query: 664 KCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDE--DECGE-------------------- 777
C +EFQC N C+P+ ++CD DDCGDNSDE +ECGE
Sbjct: 1487 HCPKDEFQCNNTLCKPQGWKCDGEDDCGDNSDENPEECGEDFYGSAFRQAVLFHRYVLIH 1546
Query: 778 ----------YRCPPGK-WNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLGCQ 924
++CPP + + C C+ K CDG +C D +DE C Q P CQ
Sbjct: 1547 SELLVCLSVIFQCPPTRQFRCLNDRVCLPLSKRCDGVNNCGDNSDELDC-QVPPPIPVCQ 1605
Query: 925 AGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCF 1104
E C +G + F C+ N+C ++G D++ N + + L DC
Sbjct: 1606 K--------HEFQCSNGRCISSIFR--CNYFNDCEDYG-SDEINCNKKD----TALNDCR 1650
Query: 1105 TLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDE------------E 1248
+ + G G + +CV N D F + R G ++ N +N E E
Sbjct: 1651 SNRTVCGDGDE-----AHCVVNGTDS---FCSCRPG-FQTNGRNRCEGAVVSALLWRRLE 1701
Query: 1249 VKKLAS-GEFIYGIDFDYGDRK----IFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLV 1413
VK G I I + T + SA + ++ + + + + L
Sbjct: 1702 VKAARDPGRLISQIRTSVCSLESAPTCATTPKDPTSAAATNISPKS--TTPARPMIPDLK 1759
Query: 1414 YPRCLAVDWITNTLYIIESGSRRIDVSSYD-GERRTVLLADGLTLPLDIALDPLRGEMFF 1590
PR +AVDW+ LY +SG I+V+ R L++ + P I +DP RG M++
Sbjct: 1760 MPRGIAVDWVAGNLYWTDSGRDVIEVAQISKTHHRKTLISGMIDEPYAIVVDPQRGRMYW 1819
Query: 1591 T---NQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGN 1761
N K+E AAMDGT R TLV + +G+ VD +R+YW D K+ + S+ G+
Sbjct: 1820 ADWGNHPKIETAAMDGTMRETLVEKNIQWPTGLAVDYFNERLYWADAKLSLICSVRLNGS 1879
Query: 1762 DRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMG 1941
D V+ PF + +F+ Y+Y + V +V KFG + + T
Sbjct: 1880 DA--------VLRQPFSIDVFEDYVYGVTYINNYVFRVNKFGKGP--IENLTTGMNHATD 1929
Query: 1942 ISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVN 2121
I YH QP ++ NPC + CE +C+LS G C CP G L N
Sbjct: 1930 IVLYHRYKQP----------EVNNPCDSKKCEWLCLLSPS------GPVCTCPNGHMLNN 1973
Query: 2122 GKRCIDS 2142
G C+++
Sbjct: 1974 G-TCVET 1979
Score = 177 bits (450), Expect = 5e-42
Identities = 103/315 (32%), Positives = 144/315 (45%), Gaps = 4/315 (1%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAE 336
C F+C G C + C Q++C + + CI
Sbjct: 1207 CRPGQFQCGTGICTNPAYICDGDNDCHDNSDEANCDIHVCLPSQFKCTSPS----RCIPG 1262
Query: 337 YQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEK 516
RC++ +C +G DEKDCP T + N F CA ++C CD DC D SDE
Sbjct: 1263 IFRCNSQDNCGEGEDEKDCPEVTC---APNQFQCAITKRCIPRVWVCDRDNDCVDGSDEP 1319
Query: 517 DSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEP-DTCEFKKCTANEFQCK 693
+C++ C +FRC D +CI W CDG DC D SDEP + C+ + C +F+CK
Sbjct: 1320 ANCTQ--MTCGVDEFRCKDSGRCIPARWKCDGEDDCGDASDEPKEECDERTCEPYQFRCK 1377
Query: 694 NKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADG 873
N RC P +++CDY +DCGDNSDED+C +C ++ C G CI CDG DCADG
Sbjct: 1378 NNRCVPGRWQCDYDNDCGDNSDEDKCVPRQCSESEFACT-NGRCIAGRWKCDGDHDCADG 1436
Query: 874 ADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINEC---AEFGYC 1044
+DE GC+ C + C + + + R+H C +C ++ C
Sbjct: 1437 SDEN----------GCEVKCDSDQY----QCKNSHCIPLRWH--CDADPDCLDGSDEEKC 1480
Query: 1045 DQLCANHRPGFTCSC 1089
D H P C
Sbjct: 1481 DSGVVRHCPKDEFQC 1495
Score = 169 bits (428), Expect = 2e-39
Identities = 102/292 (34%), Positives = 133/292 (44%), Gaps = 20/292 (6%)
Frame = +1
Query: 145 ASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVS 324
A+ VC + RC +G+C+ C +DQ+QC S
Sbjct: 332 ANRVCKKGYRRCVNGRCVGHGSWCNGRDDCGDNSDEIFCNTTLCTADQFQC-----RDGS 386
Query: 325 CIAEYQRCDNITDCADGSDEKDCPASTVDCSSQ--------NVFMCADGRQCFDVSKKCD 480
CI+ +CD DC D DE +C A+ DCSS C C+ S CD
Sbjct: 387 CISNSSKCDQKVDCEDAGDEMNCTAT--DCSSYFHLGVKGVTFQKCEFTTLCYAPSWLCD 444
Query: 481 GKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEF 660
G DC D SDE++ + C F C +CI KSW CD DC +G+DE +F
Sbjct: 445 GANDCGDFSDERNCPGSSKEKCPTPFFAC-PSGRCIPKSWTCDKENDCENGADEAHCDKF 503
Query: 661 KKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDED-ECGEYRCPPGKWNCPGTGHCIDQL 837
C+A +FQC N RC P+++ CD DDCGD+SDED +C C P + CPG+ CI Q
Sbjct: 504 --CSATQFQCANNRCIPQRWVCDGADDCGDSSDEDSQCKTKTCSPEAFQCPGSHMCIPQR 561
Query: 838 KLCDGSKDCADGADE---------QQCSQN--LCPSLGCQAGCHPSPHGGEC 960
CDG KDC DG DE CS N +C + C H +C
Sbjct: 562 WKCDGDKDCPDGTDESVKAGCVFNNTCSSNEFMCQNRQCIPKHFVCDHDNDC 613
Score = 140 bits (354), Expect = 7e-31
Identities = 92/294 (31%), Positives = 122/294 (41%), Gaps = 41/294 (13%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDE-KDCPASTVDCSSQNVFMCADGR 450
C + Q+ C + CI + +CD DC D SDE DCP F C G
Sbjct: 1167 CTASQFVCK-----NDKCIPFWWKCDTEDDCGDRSDEPADCPEFK---CRPGQFQCGTG- 1217
Query: 451 QCFDVSKKCDGKYDCRDLSDE------------------------------KDSCSRN-- 534
C + + CDG DC D SDE +D+C
Sbjct: 1218 ICTNPAYICDGDNDCHDNSDEANCDIHVCLPSQFKCTSPSRCIPGIFRCNSQDNCGEGED 1277
Query: 535 -----HTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNK 699
C QF+CA +CI + WVCD DC DGSDEP C C +EF+CK+
Sbjct: 1278 EKDCPEVTCAPNQFQCAITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDEFRCKDS 1337
Query: 700 -RCQPRKFRCDYYDDCGDNSDE--DECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCAD 870
RC P +++CD DDCGD SDE +EC E C P ++ C C+ CD DC D
Sbjct: 1338 GRCIPARWKCDGEDDCGDASDEPKEECDERTCEPYQFRCK-NNRCVPGRWQCDYDNDCGD 1396
Query: 871 GADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAE 1032
+DE +C C E C +G + R+ C ++CA+
Sbjct: 1397 NSDEDKCVPRQCSE-------------SEFACTNGRCIAGRW--KCDGDHDCAD 1435
Score = 125 bits (314), Expect = 3e-26
Identities = 81/299 (27%), Positives = 146/299 (48%), Gaps = 10/299 (3%)
Frame = +1
Query: 12796 VPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKI 12975
+P IAVD+ GNL+ ++G ++S+ + K +
Sbjct: 1760 MPRGIAVDWVAGNLYWT------DSGRDVIEVAQISKT----------------HHRKTL 1797
Query: 12976 VAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEG 13155
++G + +P A++ P GR+ ++D G H KIE A MDGT R+ +V+ + PT +A+D
Sbjct: 1798 ISGMIDEPYAIVVDPQRGRMYWADWGNHPKIETAAMDGTMRETLVEKNIQWPTGLAVDY- 1856
Query: 13156 KGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSRESKTLYVQDK 13335
R+YW D K + +V ++GS+ P+++DVFE+++Y ++ + ++ +K
Sbjct: 1857 FNERLYWADAKLSLICSVRLNGSDAVL-----RQPFSIDVFEDYVYGVTYINNYVFRVNK 1911
Query: 13336 FGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTGFACLCPDG 13515
FG+G + L + + + + +Y + + C+ +C LC+ PS G C CP+G
Sbjct: 1912 FGKGPIENLTTGMNHATDIVLYHRYKQ--PEVNNPCDSKKCEWLCLLSPS-GPVCTCPNG 1968
Query: 13516 IVPQLDGSCATQHVEALTM------PKQCKCTNGGKCRLD----GSCECTSDFEGDQCE 13662
+ +G+C L+ P +C NGG C L+ C C ++ GD+CE
Sbjct: 1969 HMLN-NGTCVETPTPTLSPIGPPSGPCLVQCLNGGSCFLNAHKQAKCRCQPNYGGDRCE 2026
Score = 122 bits (307), Expect = 2e-25
Identities = 66/179 (36%), Positives = 91/179 (49%), Gaps = 18/179 (10%)
Frame = +1
Query: 424 NVFMCADGRQCFD-------VSK---------KCDGKYDCRDLSDEKDSCSRNHTACFQY 555
N ++ ADG+QC V K KCD + DC D SDE C C
Sbjct: 1153 NFYLAADGKQCLSNCTASQFVCKNDKCIPFWWKCDTEDDCGDRSDEPADCPE--FKCRPG 1210
Query: 556 QFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKN-KRCQPRKFRCDY 732
QF+C C +++CDG DC D SDE + C+ C ++F+C + RC P FRC+
Sbjct: 1211 QFQCGTGI-CTNPAYICDGDNDCHDNSDEAN-CDIHVCLPSQFKCTSPSRCIPGIFRCNS 1268
Query: 733 YDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADE-QQCSQNLC 906
D+CG+ DE +C E C P ++ C T CI ++ +CD DC DG+DE C+Q C
Sbjct: 1269 QDNCGEGEDEKDCPEVTCAPNQFQCAITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTC 1327
Score = 116 bits (290), Expect = 2e-23
Identities = 88/327 (26%), Positives = 143/327 (42%), Gaps = 33/327 (10%)
Frame = +1
Query: 6481 VDYDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINYNMYFI 6660
+D+DY + IY + + I I S + + R S+ + LA+DW+ N+Y+
Sbjct: 864 LDFDYRQQMIYWTDVTTQGSMIRRMYINGSDVQVLHRTSLSNPD--GLAVDWVGGNLYWC 921
Query: 6661 NHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQRSFLDG 6840
D R IEVSKL+G YR +L+ + P ++AVD YLYW+D G P I R +DG
Sbjct: 922 --DKGRDTIEVSKLNGAYRTVLVNSGLREPRAVAVDVRYGYLYWSDWGDNPHIGRIGMDG 979
Query: 6841 SRREVIVSSGIAEPTDLVVDVASKMIYWSDAK--------MDGIYRVRSTGGT------- 6975
+ R +I+ I P L +D + IYW+DA+ +DG R S T
Sbjct: 980 TNRSIIIEEKITWPNGLTLDFVNDRIYWADAREDYIAFASLDGTRRHTSKTHTHTHTFEL 1039
Query: 6976 ---------PE--------LVRSDIASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSL 7104
P+ ++ DI ++L + +YWTD + + RA +L
Sbjct: 1040 KNDRYSNVAPDCCLWVRCTVLVKDIPHIFAMSLFEEYIYWTDWETKSINRA-----HKTL 1094
Query: 7105 LLSPTTVAASLKDIGDVAVFSSNNQPRASS-PCQITDNLRKSPCTQLCFATPGTQTPTCS 7281
+ T + ++L D+ ++ QP + PCQ + C+ LC +PG
Sbjct: 1095 GTNKTVLISTLHRPMDIHIYHPYRQPEVENHPCQ----MNNGGCSNLCLISPG------- 1143
Query: 7282 CARGVLKGRTCEEPDTYIMFSDGDKII 7362
G C P + + +DG + +
Sbjct: 1144 ------GGYQCACPTNFYLAADGKQCL 1164
Score = 110 bits (276), Expect = 8e-22
Identities = 75/238 (31%), Positives = 103/238 (42%), Gaps = 15/238 (6%)
Frame = +1
Query: 391 CPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCA 570
C A C+ + F C +G C + + CDG C+D SDEK S N C + RC
Sbjct: 287 CTALNTTCNVVDGFECGNG-DCINYTLTCDGMAHCKDKSDEKQSYCANR-VCKKGYRRCV 344
Query: 571 DKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGD 750
+ +C+ C+G DC D SDE C CTA++FQC++ C +CD DC D
Sbjct: 345 N-GRCVGHGSWCNGRDDCGDNSDE-IFCNTTLCTADQFQCRDGSCISNSSKCDQKVDCED 402
Query: 751 NSDEDECGEYRCPP---------GKWNCPGTGHCIDQLKLCDGSKDCADGADEQQC---S 894
DE C C C T C LCDG+ DC D +DE+ C S
Sbjct: 403 AGDEMNCTATDCSSYFHLGVKGVTFQKCEFTTLCYAPSWLCDGANDCGDFSDERNCPGSS 462
Query: 895 QNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINEC---AEFGYCDQLCA 1059
+ CP+ CPSG + + TC N+C A+ +CD+ C+
Sbjct: 463 KEKCPT-------------PFFACPSGRCIPKSW--TCDKENDCENGADEAHCDKFCS 505
Score = 103 bits (258), Expect = 9e-20
Identities = 68/240 (28%), Positives = 115/240 (47%), Gaps = 2/240 (0%)
Frame = +1
Query: 6616 KSLAIDWINYNMYFINHDAERTNIEVSKLDGTY-RKILLTTKTETPSSIAVDPVSRYLYW 6792
+ +A+DW+ N+Y+ D+ R IEV+++ T+ RK L++ + P +I VDP +YW
Sbjct: 1762 RGIAVDWVAGNLYWT--DSGRDVIEVAQISKTHHRKTLISGMIDEPYAIVVDPQRGRMYW 1819
Query: 6793 ADQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGG 6972
AD G P I+ + +DG+ RE +V I PT L VD ++ +YW+DAK+ I VR G
Sbjct: 1820 ADWGNHPKIETAAMDGTMRETLVEKNIQWPTGLAVDYFNERLYWADAKLSLICSVRLNGS 1879
Query: 6973 TPELVRSDIASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGD 7152
L + ++G + + +N + ++ + P + + + D
Sbjct: 1880 DAVLRQPFSIDVFEDYVYG--VTYINNYVFRVNKFGKGPIE--------NLTTGMNHATD 1929
Query: 7153 VAVFSSNNQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCARG-VLKGRTCEEPDT 7329
+ ++ QP ++PC C LC +P P C+C G +L TC E T
Sbjct: 1930 IVLYHRYKQPEVNNPCD------SKKCEWLCLLSP--SGPVCTCPNGHMLNNGTCVETPT 1981
Score = 100 bits (249), Expect = 1e-18
Identities = 65/234 (27%), Positives = 112/234 (47%), Gaps = 13/234 (5%)
Frame = +1
Query: 4672 EGIALDWVGRNLYWVDSSLNTIEVANLEDPK-----QRTLLVHQNVSQPRGIAVDPRKGV 4836
EG+A LYW + +TI ++ + + T++ PR +D + +
Sbjct: 30 EGLAYHRGWDMLYWTSYTTSTITRHTVDQSRWGAVDRHTVVTMSGEDHPRAFVLDECQSL 89
Query: 4837 MFWTDWG-QNPCIERASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVN 5013
MFWT+W Q+P I RA++ G++ +I+ + I PN +A+D+ +++YF+D+ LD I+
Sbjct: 90 MFWTNWNEQSPSIMRATLTGSNVIVIIGSDIRTPNGLAIDHRAEKLYFSDATLDKIERCE 149
Query: 5014 YDGSGRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSK 5193
YDG+ R VL + HP LA++ D ++++D + + KY G + +
Sbjct: 150 YDGTRRYVVLKNEPV--HPFGLAVYGDYIFWTDWVRRAVLRANKYTGGDMKLLRADIPQQ 207
Query: 5194 ALGVVAVHPVLQPVIKNNPC-------STNPCSHLCLLNNKNTFTCKCPMGEKL 5334
+G+VAV N C + C LCLL ++ C C KL
Sbjct: 208 PMGIVAV------ANDTNSCEFSMCRVNNGGCQDLCLLTSEGRVNCSCRGDRKL 255
Score = 95.9 bits (237), Expect = 3e-17
Identities = 75/272 (27%), Positives = 125/272 (45%), Gaps = 7/272 (2%)
Frame = +1
Query: 1339 SAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRR-IDVSSYDG-ER 1512
+A SA D G S++ L Y R D + T Y + +R +D S + +R
Sbjct: 17 AALSASFSDVG--------SVEGLAYHR--GWDMLYWTSYTTSTITRHTVDQSRWGAVDR 66
Query: 1513 RTVLLADGLTLPLDIALDPLRGEMFFTN----QLKLEAAAMDGTNRRTLVNTHTHQVSGI 1680
TV+ G P LD + MF+TN + A + G+N ++ + +G+
Sbjct: 67 HTVVTMSGEDHPRAFVLDECQSLMFWTNWNEQSPSIMRATLTGSNVIVIIGSDIRTPNGL 126
Query: 1681 VVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRL 1860
+D A+++Y+ D +D++E +Y G R +V + V HPFGLA++ Y++WTDW R
Sbjct: 127 AIDHRAEKLYFSDATLDKIERCEYDGTRRYVVLKNEPV--HPFGLAVYGDYIFWTDWVRR 184
Query: 1861 GVIQVEKF-GSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCE 2037
V++ K+ G D KLL ++ PMGI A E ++ N C+
Sbjct: 185 AVLRANKYTGGDMKLLRADIPQQ--PMGIVA----VANDTNSCEFSMCRV----NNGGCQ 234
Query: 2038 GMCILSKDNGGFGVGYKCACPIGQKLVNGKRC 2133
+C+L+ + C+C +KL+ C
Sbjct: 235 DLCLLTSEG-----RVNCSCRGDRKLLEDSTC 261
Score = 89.0 bits (219), Expect = 3e-15
Identities = 97/412 (23%), Positives = 168/412 (40%), Gaps = 28/412 (6%)
Frame = +1
Query: 7564 QPHAKEIRHISDMKLDWLTQKIYFT-TGRGGKVMAIDTAGEHLSTIASG--DWTYALAID 7734
+P +++ + +DW+ +Y+T +GR +A + H T+ SG D YA+ +D
Sbjct: 1752 RPMIPDLKMPRGIAVDWVAGNLYWTDSGRDVIEVAQISKTHHRKTLISGMIDEPYAIVVD 1811
Query: 7735 PCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVDFRNQKIYWA 7914
P G ++W+D G P+IE + + G R+ +V ++I P +AVD+ N+++YWA
Sbjct: 1812 PQRGRMYWADWGN-------HPKIETAAMDGTMRETLVEKNIQWPTGLAVDYFNERLYWA 1864
Query: 7915 DVNRLNIEVADYDGQNRKVIASGYRAKSLDIWDRWLYMSDPLSNGVFRIDKESGSGLENV 8094
D I +G + V+ + S+D+++ ++Y ++N VFR++K +EN+
Sbjct: 1865 DAKLSLICSVRLNGSD-AVLRQPF---SIDVFEDYVYGVTYINNYVFRVNKFGKGPIENL 1920
Query: 8095 VSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLCTVVADDIGLAASKVQ 8274
+ + ++ N + LC G +CT + + V+
Sbjct: 1921 TTGMNHATDIVLYHRYKQPEVNNPCDSKKCEWLCLLSPSG--PVCTCPNGHMLNNGTCVE 1978
Query: 8275 CSCNDTYELVQEPGKDYPTQCVLRGS-----NSEPAKECLPPY-NFQCGDGSC---ILLG 8427
+ T + P QC+ GS + + C P Y +C C G
Sbjct: 1979 -TPTPTLSPIGPPSGPCLVQCLNGGSCFLNAHKQAKCRCQPNYGGDRCEIDQCRDYCKNG 2037
Query: 8428 ATC----DSKPDCADASDENPNYCNTRSCPEDYNLCTN-RRCIDSAK-----KCNHIDDC 8577
TC P C + CN +C N C N C S+ +C+H D
Sbjct: 2038 GTCTPSPTGSPTCRCLTGFTGRNCNLHTCK---NYCKNGGNCTVSSGNQPTCQCSH-DFL 2093
Query: 8578 GDGSDELDCP-----SAVACAEGTFPCSNGHCI-NQTKVCDGHNDCHDEQVS 8715
GD +CP A + C +G CI + + G C Q S
Sbjct: 2094 GDQCQYSECPFMLYTGATCEIDKCHYCRDGECIPSNSFTSRGDFTCRSSQPS 2145
Score = 84.7 bits (208), Expect = 6e-14
Identities = 75/306 (24%), Positives = 128/306 (41%), Gaps = 6/306 (1%)
Frame = +1
Query: 2404 MSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRD-PVSVVVHPWKGL 2580
++ DW++ LY+ D+ R+ +EV +I +T R+ LI+ + D P ++VV P +G
Sbjct: 1764 IAVDWVAGNLYWTDSGRDVIEVAQISKTHH-------RKTLISGMIDEPYAIVVDPQRGR 1816
Query: 2581 LFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDF 2760
+++A+ I +DG + + + P+ +A+D+ RL W D L I +
Sbjct: 1817 MYWADWGNHPKIETAAMDGTMRETLVEKNIQWPTGLAVDYFNERLYWADAKLSLICSVRL 1876
Query: 2761 DGKNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIF 2940
+G + V P +I + +Y+Y V Y V + N G +
Sbjct: 1877 NGSDAVLRQ-----PFSIDVFEDYVYGV---TYINNYVFRVNKFGKGPIENLTTGMNHAT 1928
Query: 2941 SLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINKENNH 3120
+ QP +PC + +C LC +PS C C G M+ NN
Sbjct: 1929 DIVLYHRYKQP----EVNNPCDSKKCEWLCLLSPS-------GPVCTCPNGHML---NNG 1974
Query: 3121 SCQKDPAEKIEQL-CSSNSTQFQCKN-GRCI---PKEWKCDGENDCLDESDEIDEKGDKC 3285
+C + P + + S QC N G C K+ KC + + + EID+ D C
Sbjct: 1975 TCVETPTPTLSPIGPPSGPCLVQCLNGGSCFLNAHKQAKCRCQPNYGGDRCEIDQCRDYC 2034
Query: 3286 FHETEC 3303
+ C
Sbjct: 2035 KNGGTC 2040
Score = 73.6 bits (179), Expect = 1e-10
Identities = 49/177 (27%), Positives = 80/177 (44%), Gaps = 4/177 (2%)
Frame = +1
Query: 5875 VARAGLDGSNPLVIASNDLAELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSD 6054
+ RA L GSN +VI +D+ + +AID ++YFS+A +I YDG R+ VL +
Sbjct: 102 IMRATLTGSNVIVIIGSDIRTPNGLAIDHRAEKLYFSDATLDKIERCEYDGTRRYVVLKN 161
Query: 6055 GGRQPNGLAFYGDRLFYADSAFDSIEVAT--INGDSQPPQWTHFKKDV--ENLANIKALQ 6222
P GLA YGD +F+ D ++ A GD + + D+ + + +
Sbjct: 162 EPVHPFGLAVYGDYIFWTDWVRRAVLRANKYTGGDMK-----LLRADIPQQPMGIVAVAN 216
Query: 6223 PRASSSGHPCHINNGNCDHICIPLMFAQRTCTCANGYVKDGQTSCKLFDESFVIVAT 6393
S C +NNG C +C+ + C+C ++C + SF + T
Sbjct: 217 DTNSCEFSMCRVNNGGCQDLCLLTSEGRVNCSCRGDRKLLEDSTCSGYTTSFFFLLT 273
Score = 73.2 bits (178), Expect = 2e-10
Identities = 94/424 (22%), Positives = 160/424 (37%), Gaps = 64/424 (15%)
Frame = +1
Query: 5254 STNPCSHLCLLNNKNTFTCKCPMGEKLDASGK---KCIDDAKPFLVI-----IQKTNVFG 5409
+T PC+ C+ N +F C C G L K D +PFL+ ++K N+ G
Sbjct: 757 TTYPCTQRCI-NTHGSFHCLCVEGYHLSPENPTICKSTSDEEPFLIFANRYYLRKLNLDG 815
Query: 5410 IE-------------MNSASEKET------PVLAGMVPLS-GLGNAFDAAYDALSEEMFI 5529
+ + K+T P L + L GL NA +D + ++
Sbjct: 816 SNYTLLKQVRLAFTLFSGVALKDTRRVCCGPRLTELHVLQQGLNNAVALDFDYRQQMIYW 875
Query: 5530 LEHTNHAKTLAQITTDSAIYRSTVNGGNKTKMFSSAV--PDDAYCLGFDWNGRNLVVGNK 5703
+ T T S I R +NG + + +++ PD L DW G NL +K
Sbjct: 876 TDVT---------TQGSMIRRMYINGSDVQVLHRTSLSNPDG---LAVDWVGGNLYWCDK 923
Query: 5704 ITQTIEIIRTQGKQYRSVILSNDQSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVAR 5883
TIE+ + G YR+V++++ GY++W D G + + R
Sbjct: 924 GRDTIEVSKLNGA-YRTVLVNSGLREPRAVAVDVRY-----GYLYWSDWGD---NPHIGR 974
Query: 5884 AGLDGSNPLVIASNDLAELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGR 6063
G+DG+N +I + + + +D N R+Y+++A+ I+ + DG RH S
Sbjct: 975 IGMDGTNRSIIIEEKITWPNGLTLDFVNDRIYWADAREDYIAFASLDGTRRH--TSKTHT 1032
Query: 6064 QPNGLAFYGDRLFYADSAFDSI-------------EVATINGDSQPPQWTHFKKDVENLA 6204
+ DR Y++ A D + ++ + WT ++ N A
Sbjct: 1033 HTHTFELKNDR--YSNVAPDCCLWVRCTVLVKDIPHIFAMSLFEEYIYWTDWETKSINRA 1090
Query: 6205 -------------------NIKALQP--RASSSGHPCHINNGNCDHICIPLMFAQRTCTC 6321
+I P + HPC +NNG C ++C+ C C
Sbjct: 1091 HKTLGTNKTVLISTLHRPMDIHIYHPYRQPEVENHPCQMNNGGCSNLCLISPGGGYQCAC 1150
Query: 6322 ANGY 6333
+
Sbjct: 1151 PTNF 1154
Score = 69.7 bits (169), Expect = 2e-09
Identities = 64/241 (26%), Positives = 103/241 (42%), Gaps = 5/241 (2%)
Frame = +1
Query: 6634 WINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTET-PSSIAVDPVSRYLYWADQG-Q 6807
W +Y I R ++ S+ R ++T E P + +D ++W + Q
Sbjct: 43 WTSYTTSTIT----RHTVDQSRWGAVDRHTVVTMSGEDHPRAFVLDECQSLMFWTNWNEQ 98
Query: 6808 KPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPELV 6987
P+I R+ L GS VI+ S I P L +D ++ +Y+SDA +D I R G +V
Sbjct: 99 SPSIMRATLTGSNVIVIIGSDIRTPNGLAIDHRAEKLYFSDATLDKIERCEYDGTRRYVV 158
Query: 6988 -RSDIASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVF 7164
+++ G+A++G ++WTD + RA LL + +G VAV
Sbjct: 159 LKNEPVHPFGLAVYGDYIFWTDWVRRAVLRANKYTGGDMKLL---RADIPQQPMGIVAVA 215
Query: 7165 SSNNQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCA--RGVLKGRTCEEPDTYIM 7338
+ N S C++ + C LC T + CSC R +L+ TC T
Sbjct: 216 NDTNSCEFSM-CRVNN----GGCQDLCLLTSEGRV-NCSCRGDRKLLEDSTCSGYTTSFF 269
Query: 7339 F 7341
F
Sbjct: 270 F 270
Score = 66.2 bits (160), Expect = 2e-08
Identities = 47/150 (31%), Positives = 75/150 (49%), Gaps = 4/150 (2%)
Frame = +1
Query: 6619 SLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWAD 6798
+L D+ +Y+ + + + I ++G+ ++L T P +AVD V LYW D
Sbjct: 863 ALDFDYRQQMIYWTDVTTQGSMIRRMYINGSDVQVLHRTSLSNPDGLAVDWVGGNLYWCD 922
Query: 6799 QGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSD-AKMDGIYRVRSTGGT 6975
+G + TI+ S L+G+ R V+V+SG+ EP + VDV +YWSD I R+ G
Sbjct: 923 KG-RDTIEVSKLNGAYRTVLVNSGLREPRAVAVDVRYGYLYWSDWGDNPHIGRIGMDGTN 981
Query: 6976 PE-LVRSDIASAAGVALHGQN--MYWTDNR 7056
++ I G+ L N +YW D R
Sbjct: 982 RSIIIEEKITWPNGLTLDFVNDRIYWADAR 1011
Score = 54.7 bits (130), Expect = 7e-05
Identities = 41/157 (26%), Positives = 81/157 (51%), Gaps = 5/157 (3%)
Frame = +1
Query: 6544 ITAYTIGESSPRAVIRDSIGSLT----IKSLAIDWINYNMYFINHDAERTNIEVSKLDGT 6711
IT +T+ +S AV R ++ +++ ++ +D M++ N + + +I + L G+
Sbjct: 51 ITRHTVDQSRWGAVDRHTVVTMSGEDHPRAFVLDECQSLMFWTNWNEQSPSIMRATLTGS 110
Query: 6712 YRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQRSFLDGSRREVIVSSGIAEPTDL 6891
+++ + TP+ +A+D + LY++D I+R DG+RR V++ + P L
Sbjct: 111 NVIVIIGSDIRTPNGLAIDHRAEKLYFSD-ATLDKIERCEYDGTRRYVVLKNEPVHPFGL 169
Query: 6892 VVDVASKMIYWSDAKMDGIYRV-RSTGGTPELVRSDI 6999
V I+W+D + R + TGG +L+R+DI
Sbjct: 170 A--VYGDYIFWTDWVRRAVLRANKYTGGDMKLLRADI 204
Score = 45.8 bits (107), Expect = 0.030
Identities = 51/234 (21%), Positives = 96/234 (40%), Gaps = 3/234 (1%)
Frame = +1
Query: 5659 LGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVILSNDQSXXXXXXXXXXXXXXXKGYVF 5838
+ DW NL + IE+ + +R ++S +G ++
Sbjct: 1764 IAVDWVAGNLYWTDSGRDVIEVAQISKTHHRKTLISG-----MIDEPYAIVVDPQRGRMY 1818
Query: 5839 WLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAIDTTNTRVYFSEAKAGRISSVT 6018
W D G K+ A +DG+ + ++ +A+D N R+Y+++AK I SV
Sbjct: 1819 WADWGN---HPKIETAAMDGTMRETLVEKNIQWPTGLAVDYFNERLYWADAKLSLICSVR 1875
Query: 6019 YDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAFDSIEVATINGDSQPP---QWTHFKKD 6189
+G D VL RQP + + D ++ + + V +N + P T
Sbjct: 1876 LNGSDA--VL----RQPFSIDVFEDYVY--GVTYINNYVFRVNKFGKGPIENLTTGMNHA 1927
Query: 6190 VENLANIKALQPRASSSGHPCHINNGNCDHICIPLMFAQRTCTCANGYVKDGQT 6351
+ + + QP + +PC ++ C+ +C+ L + CTC NG++ + T
Sbjct: 1928 TDIVLYHRYKQPEVN---NPC--DSKKCEWLCL-LSPSGPVCTCPNGHMLNNGT 1975
Score = 39.3 bits (90), Expect = 2.8
Identities = 26/95 (27%), Positives = 36/95 (37%), Gaps = 23/95 (24%)
Frame = +1
Query: 4210 DRAGCSFKCHNSPNGPICSCPFGEQLVNKTKCEPEN---------------ECLDSSSC- 4341
D C + C SP+GP+C+CP G L N T E +CL+ SC
Sbjct: 1946 DSKKCEWLCLLSPSGPVCTCPNGHMLNNGTCVETPTPTLSPIGPPSGPCLVQCLNGGSCF 2005
Query: 4342 -------SQRCKDEKHGFTCSCDEGYELDVDKRTC 4425
RC+ G C D+ + + TC
Sbjct: 2006 LNAHKQAKCRCQPNYGGDRCEIDQCRDYCKNGGTC 2040
>gi|1083645|pir||S53457 dominant autoantigen gp 330 - rat (fragment)
gi|998942|gb|AAB33315.1| Heymann nephritis autoantigen gp330
{C-terminal} [rats, kidney, Peptide Partial, 1650 aa]
Length = 1650
Score = 914 bits (2362), Expect = 0.0
Identities = 568/1716 (33%), Positives = 837/1716 (48%), Gaps = 75/1716 (4%)
Frame = +1
Query: 9334 CIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCANHKCVPNSWKCDGNDDCEDGSDE 9513
C+ ++ CD NDC D SDE C+Y C + F C N +C+P + CD ++DC DGSDE
Sbjct: 2 CVRQSFRCDRRNDCGDYSDERG-CSYPPCHANQFTCQNGRCIPRFFVCDEDNDCGDGSDE 60
Query: 9514 KDCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAE 9693
++ ++ C QF+C +G CI+ +VC+ DC+D SDE C I+EC +
Sbjct: 61 QEHLCHTPEPT----CPLHQFRCDNGHCIEMGRVCNHVDDCSDNSDEKG-CGINECLDSS 115
Query: 9694 KPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCG 9873
C+ C D + C C G+ + +SD++SC +++EC E CSQKC++ +GSY C
Sbjct: 116 ISRCDHNCTDTITSFYCSCLPGYKL-MSDKRSCVDIDECKESPQLCSQKCENVVGSYICK 174
Query: 9874 CVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYELAAQGFDNVVSLDIDL 10053
C GY D SC++ EP+ + +N++YIR ++ DG+ Y L QG NVV+LD D
Sbjct: 175 CAPGYIREPDGKSCRQNS-NIEPYLIFSNRYYIRNLTTDGSSYSLILQGLGNVVALDFDR 233
Query: 10054 TEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQE 10233
EK+ Y ID K + R+ L++ ++ ET++ H + E + VDWV KLY L+
Sbjct: 234 VEKRLYWIDAEKQIIERMFLNK-----TNRETIINHRLRRAESLDVDWVSTKLYWLDAIL 288
Query: 10234 RSIRVCELDGRFCKTLIRDRI--------QQPKAIVVHPGKGYLFFTEWSLQPYIGRIAL 10389
+ V +L+GR K + + + + P+ IV+HP +G++++T+W + YIGRI +
Sbjct: 289 DCLFVSDLEGRHRKMIAQHCVDANNTFCFEHPRGIVLHPQRGHVYWTDWGVHAYIGRIGM 348
Query: 10390 DGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHIPAQR 10569
DG+ + + + WPNAI IDY +D L+W DAHL I F D +G+ R +
Sbjct: 349 DGTNKSV-----IISTKIEWPNAITIDYTNDLLYWADAHLGYIEFSDLEGHHRHTVYDGS 403
Query: 10570 TSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDLRIVHPMRQPAYP 10749
H ++ +F+D ++W DWN R V + +K+ G +L T P D+ + HP RQP
Sbjct: 404 LPHPFALTIFEDTVFWTDWNTRTVEKGNKYDGSGRVVLVNTTHKPFDIHVYHPYRQPIMS 463
Query: 10750 NPCGDNNGGCSHLCLIGAGGNGYTCSCPDQF--VLLSDQKTCEPNCTERQFACGGDDAKC 10923
NPCG NNGGCSHLCLI AGG G+TC+CPD F V L D+ C P C+ +QF CG ++ KC
Sbjct: 464 NPCGTNNGGCSHLCLIKAGGRGFTCACPDDFQTVQLRDRTLCMPMCSSQQFLCGNNE-KC 522
Query: 10924 IPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXX 11103
IP W CDG+ DC DGSDEP +C R C +G+FQC + NCT P +
Sbjct: 523 IPIWWKCDGQKDCSDGSDEP--DLCPHRFCRLGQFQCRDGNCTSPQALCNARQDCADGSD 580
Query: 11104 EQN--CD-----KACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEADTLCMSAERNCT 11262
E C+ C+ ++C A RCIP+ + SDE + C A R C
Sbjct: 581 EDRVLCEHHRVSHECESNEWQC-ANKRCIPQSWQCDSVNDCLDNSDEDTSHC--ASRTCR 637
Query: 11263 AEEFRCNNNKCIAKAWRXXXXXXXXXXXXE-TPEC--AQIECKKGWT-RCSSSYRCIPNW 11430
+F+CNN +CI ++W+ E EC A C C ++YRCIP W
Sbjct: 638 PGQFKCNNGRCIPQSWKCDVDNDCGDYSDEPIDECTTAAYNCDNHTEFSCKTNYRCIPQW 697
Query: 11431 AFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDAS 11610
A CNG DDCR+NSDE C G+FRCA + CIP RW CD +DCGDNSDE +
Sbjct: 698 AVCNGFDDCRENSDEQGCESVPCHPSGDFRCA-NHHCIPLRWKCDGTDDCGDNSDEENC- 755
Query: 11611 CGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQCDDGTCI 11790
R CSESEFRC D +CIP VCD C D DE C ++ C P H QC G C+
Sbjct: 756 ---VPRECSESEFRCADQQCIPSRWVCDQENDCGDNSDERDCEMKTCHPEHFQCTSGHCV 812
Query: 11791 AEHKWCDRKKDCPNAADELHCED--VSRRTCSPFEFECANSVCIPRKFMXXXXXXXXXXS 11964
+ CD + DC +A+DE C + C FEC N VCI ++ S
Sbjct: 813 PKALACDGRADCLDASDESACPTRFPNGTYCPAAMFECKNHVCIQSFWICDGENDCVDGS 872
Query: 11965 DETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSFSEYGD 12144
DE C + C+ P RFRC +SR C+ QLCNG +DCG D SDE C +
Sbjct: 873 DEEIHLCFNIPCESPQRFRCDNSR-CVYGHQLCNGVDDCG--DGSDEKEEHCRK-PTHKP 928
Query: 12145 CSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKHICTDV 12324
C+ ++KC+NG C++ CD +DCGD SDE GC+ +T E C+ CT +
Sbjct: 929 CTDTEYKCSNGNCISQHYVCDNVNDCGDLSDETGCNLGDNRTCAENI-----CEQNCTQL 983
Query: 12325 RD-GFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGSYLCRCHEDYENNVVV 12501
GF C CR GF+P C DI+EC C Q C N+KGSY C C + +++ +
Sbjct: 984 SSGGFICSCRPGFKPSTSDKNSCQDINECEEFGICPQSCRNSKGSYECFCVDGFKS---M 1040
Query: 12502 GSMTGKDCRAKGDAANVMIGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXXXXPRK- 12678
+ G+ C A G +++ + V++ + + + + P
Sbjct: 1041 STHYGERCAADGSPPLLLLPEN---VRIRKYNTSSEKFSEYLEEEEHIQTIDYDWDPEHI 1097
Query: 12679 --ELMYW---IDGSE-RTIYRSAIANGNQSHEGQKLDVDFAAMGVV-PTAIAVDYTTGNL 12837
++Y+ GS+ I R+ I N +VD ++ P +AVD+ ++
Sbjct: 1098 GLSVVYYTVLAQGSQFGAIKRAYIPNFESGSNNPIREVDLGLKYLMQPDGLAVDWVGRHI 1157
Query: 12838 FIA-AVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALIT 13014
+ + A S+ IE V DGRY ++ L QP + +
Sbjct: 1158 YWSDAKSQRIE------------------------VATLDGRYRNWLITTQLDQPRSYV- 1192
Query: 13015 APSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYR 13194
D G KIE A M+G HR ++V + + P ++ID +R+YW D K
Sbjct: 1193 --------LDDQGKQPKIESAWMNGEHRSVLVSENLGWPNGLSIDYLNDDRVYWSDSKED 1244
Query: 13195 RVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSRESKTLYVQDKFGRGR------VS 13356
++A+ DG++R ++++ P+++D+FE+ +YW+++E ++ Q+KFG+ V+
Sbjct: 1245 VIEAIKYDGTDRRLIINEAMKPFSLDIFEDKLYWVAKEKGEVWRQNKFGKENKEKVLVVN 1304
Query: 13357 VLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTGFACLCPDG--IVPQL 13530
+ + H +R Q +VS + CSHLC+ P G++C CP G V
Sbjct: 1305 PWLTQVRIFHQLRYKQ--------SVSNPCKQVCSHLCLLRPG-GYSCACPQGSDFVTGS 1355
Query: 13531 DGSCATQHVEALTMPKQCKCTNGGKCRLDGS----CECTSDFEGDQCEKESSVSRKI-IG 13695
C +TMP C+C +GG C D + C+C+S + G+ C E +SR I G
Sbjct: 1356 TVQCDAASELPVTMPPPCRCMHGGNCYFDENELPKCKCSSGYSGEYC--EVGLSRGIPPG 1413
Query: 13696 TLSENFIT------VXXXXXXXXXXXXXXXXXXXNLYKRRQL--LFKKNEAADG------ 13833
T +T V L K L L K +E +G
Sbjct: 1414 TTMAVLLTFVIVIIVGALVLVGLFHYRKTGSLLPTLPKLPSLSSLAKPSENGNGVTFRSG 1473
Query: 13834 -SVSFHGNVISFSNPVLENKQDAPGSEFNMQQMTSMHDDSTTFTNPVYELEDVDMSSPPP 14010
V+ V F + ++ A F M+ + F NP+Y +D
Sbjct: 1474 ADVNMDIGVSPFGPETIIDRSMAMNEHFVME----VGKQPVIFENPMYAAKD-------- 1521
Query: 14011 SNDQPSTSASAMSPNRPSTSAASSFVPPTFDQDEIELKTADEIIVPKAEISKPPIPARP- 14187
+TS A++ PST A + VP + +E + I P +EI P PA P
Sbjct: 1522 -----NTSKVALAVQGPSTGAQVT-VP-----ENVENQNYGRPIDP-SEIVPEPKPASPG 1569
Query: 14188 ------------KKEKADPLRVDNPLY-DPDSEVSD 14256
K++ +NP+Y + DSEV D
Sbjct: 1570 ADEIQGKKWNIFKRKPKQTTNFENPIYAEMDSEVKD 1605
Score = 502 bits (1293), Expect = e-140
Identities = 381/1295 (29%), Positives = 583/1295 (44%), Gaps = 83/1295 (6%)
Frame = +1
Query: 7198 CQITDNLRKSP--CTQLCFATPGTQTPTCSCARGVLK---GRTCEEP---DTYIMFSDGD 7353
C D ++SP C+Q C G+ C CA G ++ G++C + + Y++FS+
Sbjct: 147 CVDIDECKESPQLCSQKCENVVGSYI--CKCAPGYIREPDGKSCRQNSNIEPYLIFSNRY 204
Query: 7354 KIIDVAIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAE 7533
I ++ + S L+ + N+ D D +R+Y++ + + + N E
Sbjct: 205 YIRNLTTDGS-SYSLILQG----LGNVVALDFDRVEKRLYWIDAEKQIIERMFLNKTNRE 259
Query: 7534 ---NPRLVFGASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTIAS 7704
N RL R + +DW++ K+Y+ + D G H IA
Sbjct: 260 TIINHRL-------------RRAESLDVDWVSTKLYWLDAILDCLFVSDLEGRHRKMIAQ 306
Query: 7705 G----------DWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSE 7854
+ + + P G ++W+D G G R + G ++ VI+S
Sbjct: 307 HCVDANNTFCFEHPRGIVLHPQRGHVYWTDWGVHAYIG-------RIGMDGTNKSVIIST 359
Query: 7855 SISLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGY--RAKSLDIWDRWLYM 8028
I P AI +D+ N +YWAD + IE +D +G +R + G +L I++ ++
Sbjct: 360 KIEWPNAITIDYTNDLLYWADAHLGYIEFSDLEGHHRHTVYDGSLPHPFALTIFEDTVFW 419
Query: 8029 SDPLSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDN 8208
+D + V + +K GSG +V+ P D+ + + S C T+N
Sbjct: 420 TDWNTRTVEKGNKYDGSGRVVLVNTTHKP---------FDIHVYHPYRQPIMSNPCGTNN 470
Query: 8209 GGCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDY-----PTQCVLRGSNS----- 8358
GGC LC + A G C+C D ++ VQ + +Q L G+N
Sbjct: 471 GGCSHLCLIKAGGRGFT-----CACPDDFQTVQLRDRTLCMPMCSSQQFLCGNNEKCIPI 525
Query: 8359 ----EPAKEC--------LPPY------NFQCGDGSCILLGATCDSKPDCADASDENPNY 8484
+ K+C L P+ FQC DG+C A C+++ DCAD SDE+
Sbjct: 526 WWKCDGQKDCSDGSDEPDLCPHRFCRLGQFQCRDGNCTSPQALCNARQDCADGSDEDRVL 585
Query: 8485 CN----TRSCPEDYNLCTNRRCIDSAKKCNHIDDCGDGSDE--LDCPSAVACAEGTFPCS 8646
C + C + C N+RCI + +C+ ++DC D SDE C S C G F C+
Sbjct: 586 CEHHRVSHECESNEWQCANKRCIPQSWQCDSVNDCLDNSDEDTSHCASR-TCRPGQFKCN 644
Query: 8647 NGHCINQTKVCDGHNDCHDEQVSDESLATCPGLPIDC-RGVKVRCPNTNICIQPADLCDG 8823
NG CI Q+ CD NDC D SDE + C +C + C CI +C+G
Sbjct: 645 NGRCIPQSWKCDVDNDCGD--YSDEPIDECTTAAYNCDNHTEFSCKTNYRCIPQWAVCNG 702
Query: 8824 YDDCGDKADENQLFCMNQQC-AQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDT 9000
+DDC + +DE C + C RC + CIP W+CDG +DC D DE NC
Sbjct: 703 FDDCRENSDEQG--CESVPCHPSGDFRCANHHCIPLRWKCDGTDDCGDNSDE--ENCVPR 758
Query: 9001 AGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNA 9180
+ F+C + +CI ++ C +TC + F CTS
Sbjct: 759 E-----CSESEFRCADQQCIPSRWVCDQENDCGDNS---DERDCEMKTCHPEHFQCTSG- 809
Query: 9181 KLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKE---CNKGEFRCSNQHCIHSTW 9351
C+P+A CDG C DES C T C F C N CI S W
Sbjct: 810 -------HCVPKALACDGRADCLDASDESA--CPTRFPNGTYCPAAMFECKNHVCIQSFW 860
Query: 9352 ECDGDNDCLDGSDEHAN-CTYSSCQ-PDFFQCANHKCVPNSWKCDGNDDCEDGSDEKD-- 9519
CDG+NDC+DGSDE + C C+ P F+C N +CV C+G DDC DGSDEK+
Sbjct: 861 ICDGENDCVDGSDEEIHLCFNIPCESPQRFRCDNSRCVYGHQLCNGVDDCGDGSDEKEEH 920
Query: 9520 CPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKP 9699
C K + C++ +++C++G CI VCD DC D SDE+ D + AE
Sbjct: 921 CRKPT-----HKPCTDTEYKCSNGNCISQHYVCDNVNDCGDLSDETGCNLGDNRTCAEN- 974
Query: 9700 LCEQKCMDMKI-GYKCDCFEGFAIDISDQKSCHNVNECYE-GISGCSQKCDDKIGSYKCG 9873
+CEQ C + G+ C C GF SD+ SC ++NEC E GI C Q C + GSY+C
Sbjct: 975 ICEQNCTQLSSGGFICSCRPGFKPSTSDKNSCQDINECEEFGI--CPQSCRNSKGSYECF 1032
Query: 9874 CVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYELAAQGFDNVVSLDID- 10050
CVDG++ S + + P LL IRK + K+ + +++ ++D D
Sbjct: 1033 CVDGFKSMSTHYGERCAADGSPPLLLLPENVRIRKYNTSSEKFSEYLEEEEHIQTIDYDW 1092
Query: 10051 ------LTEKKAYLIDQGKL--RLLRVDLDEMDS----PLSSYETVLRHNVYGTEGIAVD 10194
L+ ++ QG + R + +S P+ + L++ + +G+AVD
Sbjct: 1093 DPEHIGLSVVYYTVLAQGSQFGAIKRAYIPNFESGSNNPIREVDLGLKY-LMQPDGLAVD 1151
Query: 10195 WVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFFTEWSLQPYI 10374
WVGR +Y + + + I V LDGR+ LI ++ QP++ V+ + QP I
Sbjct: 1152 WVGRHIYWSDAKSQRIEVATLDGRYRNWLITTQLDQPRSYVL---------DDQGKQPKI 1202
Query: 10375 GRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFS-DRLFWGDAHLNEIGFMDFDGNGRR 10551
++G L +LGWPN ++IDY + DR++W D+ + I + +DG RR
Sbjct: 1203 ESAWMNGEHR-----SVLVSENLGWPNGLSIDYLNDDRVYWSDSKEDVIEAIKYDGTDRR 1257
Query: 10552 HIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDLRIVHPM 10731
I S+ +F+D LYW EV R +K+ +N+ + +RI H +
Sbjct: 1258 LI-INEAMKPFSLDIFEDKLYWVAKEKGEVWRQNKFGKENKEKVLVVNPWLTQVRIFHQL 1316
Query: 10732 R-QPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCP 10833
R + + NPC CSHLCL+ G GY+C+CP
Sbjct: 1317 RYKQSVSNPC---KQVCSHLCLLRPG--GYSCACP 1346
Score = 343 bits (881), Expect = 5e-92
Identities = 312/1230 (25%), Positives = 488/1230 (39%), Gaps = 149/1230 (12%)
Frame = +1
Query: 2083 YKCACPIGQ-KLVNGKRCIDSID---YLLFSSNKIVRGIFPEINEKALAEAVLPISPISQ 2250
Y C C G + +GK C + + YL+FS+ +R + + + +L
Sbjct: 171 YICKCAPGYIREPDGKSCRQNSNIEPYLIFSNRYYIRNLTTDGSSYSLI----------L 220
Query: 2251 RRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWISKQ 2430
+ +G ++ D ++ D I R+ + ++ S+ DW+S +
Sbjct: 221 QGLGNVVALDFDRVEKRLYWIDAEKQIIERMFLNKTNRETIINHRLRRAESLDVDWVSTK 280
Query: 2431 LYYVDNIRNSLEVVKI-GETGLVHPDELVRRQLITELRDPVSVVVHPWKGLLFYAEAMRP 2607
LY++D I + L V + G + V P +V+HP +G +++ +
Sbjct: 281 LYWLDAILDCLFVSDLEGRHRKMIAQHCVDANNTFCFEHPRGIVLHPQRGHVYWTDWGVH 340
Query: 2608 AAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVKL- 2784
A I R +DG N VI +T + P+ + ID+ + L W D L I D +G + +
Sbjct: 341 AYIGRIGMDGTNKSVIISTKIEWPNAITIDYTNDLLYWADAHLGYIEFSDLEGHHRHTVY 400
Query: 2785 DIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQ 2964
D P P A+TI + +++ ++ + +K +G G ++ F +
Sbjct: 401 DGSLPHPFALTIFEDTVFWTDWNTRTVEKGNKYDGSGRVVLVN---TTHKPFDIHVYHPY 457
Query: 2965 NQPIPDDSREHPCRASQ--CTQLCF----------ATPSESHPNELEAKCACR-----QG 3093
QPI +PC + C+ LC A P + +L + C Q
Sbjct: 458 RQPI----MSNPCGTNNGGCSHLCLIKAGGRGFTCACPDDFQTVQLRDRTLCMPMCSSQQ 513
Query: 3094 FMINKENNHSC---------QKDPAEKIEQ--LCSSNST---QFQCKNGRCIPKEWKCDG 3231
F+ NN C QKD ++ ++ LC QFQC++G C + C+
Sbjct: 514 FLCG--NNEKCIPIWWKCDGQKDCSDGSDEPDLCPHRFCRLGQFQCRDGNCTSPQALCNA 571
Query: 3232 ENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKY 3411
DC D SDE + EC N +C N K+CIP +
Sbjct: 572 RQDCADGSDEDRVLCEHHRVSHECESNEWQCAN-KRCIPQSWQCDSVNDCLDNSDEDTSH 630
Query: 3412 CKDGQKPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNA----------TC 3561
C C +F+C+N RCIP+ WK E ++ C A +C
Sbjct: 631 CASR---TCRPGQFKCNNGRCIPQSWKCDVDNDCGDYSDEPIDECTTAAYNCDNHTEFSC 687
Query: 3562 AAN----------------------------------QFSCANGRCIPIYWLCDGDNDCY 3639
N F CAN CIP+ W CDG +DC
Sbjct: 688 KTNYRCIPQWAVCNGFDDCRENSDEQGCESVPCHPSGDFRCANHHCIPLRWKCDGTDDCG 747
Query: 3640 DGTDEDKERCPPVQCSALQFRCANGRQCVPLRNHXXXXXXXXXXXXXXXXAVTAESCTPD 3819
D +DE E C P +CS +FRCA+ +QC+P R ++C P+
Sbjct: 748 DNSDE--ENCVPRECSESEFRCAD-QQCIPSR--WVCDQENDCGDNSDERDCEMKTCHPE 802
Query: 3820 QFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCT--SGRQCSSDQFKCGNGRCILNNWL 3993
F+C +SG C+P + SDE +G C + F+C N CI + W+
Sbjct: 803 HFQC-TSGHCVPKALACDGRADCLDASDESACPTRFPNGTYCPAAMFECKNHVCIQSFWI 861
Query: 3994 CDGENDCGDGSDESSER----GCKTSMNAR----KCPFEHVACENDQE------------ 4113
CDGENDC DGSDE C++ R +C + H C +
Sbjct: 862 CDGENDCVDGSDEEIHLCFNIPCESPQRFRCDNSRCVYGHQLCNGVDDCGDGSDEKEEHC 921
Query: 4114 ------------------TCIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCSFKCH 4239
CI H +CD C +DE G D + C C
Sbjct: 922 RKPTHKPCTDTEYKCSNGNCISQHYVCDNVNDCGDLSDETGCNLGDNRTCAENICEQNCT 981
Query: 4240 N-SPNGPICSCP--FGEQLVNKTKCEPENECLDSSSCSQRCKDEKHGFTCSCDEGYE--- 4401
S G ICSC F +K C+ NEC + C Q C++ K + C C +G++
Sbjct: 982 QLSSGGFICSCRPGFKPSTSDKNSCQDINECEEFGICPQSCRNSKGSYECFCVDGFKSMS 1041
Query: 4402 -----------------LDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGAI 4530
L + R K + + Y+ I D+ D H ++
Sbjct: 1042 THYGERCAADGSPPLLLLPENVRIRKYNTSSEKFSEYLEEEEHIQTIDYDWDPEHIGLSV 1101
Query: 4531 VENAIALAWDSLTDRIYWSDIREKKILSANRNGTNATVFIADGLDI---TEGIALDWVGR 4701
V + L + I+ I + N + GL +G+A+DWVGR
Sbjct: 1102 VYYTV------LAQGSQFGAIKRAYIPNFESGSNNPIREVDLGLKYLMQPDGLAVDWVGR 1155
Query: 4702 NLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQNPCIERA 4881
++YW D+ IEVA L D + R L+ + QPR +D D G+ P IE A
Sbjct: 1156 HIYWSDAKSQRIEVATL-DGRYRNWLITTQLDQPRSYVLD---------DQGKQPKIESA 1205
Query: 4882 SMDGTDRQIIVKTKIYWPNTIALDY-TTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKF 5058
M+G R ++V + WPN +++DY DRVY++DSK D I+ + YDG+ R ++ +
Sbjct: 1206 WMNGEHRSVLVSENLGWPNGLSIDYLNDDRVYWSDSKEDVIEAIKYDGTDRRLIINEA-- 1263
Query: 5059 VQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAV-HPVLQPV 5235
P +L IFED +Y+ + +K +V+ + G ++ + L V + H +
Sbjct: 1264 -MKPFSLDIFEDKLYWVAK--EKGEVWRQNKFGKENKEKVLVVNPWLTQVRIFHQLRYKQ 1320
Query: 5236 IKNNPCSTNPCSHLCLLNNKNTFTCKCPMG 5325
+NPC CSHLCLL ++C CP G
Sbjct: 1321 SVSNPCK-QVCSHLCLL-RPGGYSCACPQG 1348
Score = 283 bits (723), Expect = 1e-73
Identities = 173/506 (34%), Positives = 265/506 (52%), Gaps = 15/506 (2%)
Frame = +1
Query: 3847 CIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKCGNGRCILNNWLCDGENDCGDGS 4026
C+ S++ SDE GC S C ++QF C NGRCI ++CD +NDCGDGS
Sbjct: 2 CVRQSFRCDRRNDCGDYSDER--GC-SYPPCHANQFTCQNGRCIPRFFVCDEDNDCGDGS 58
Query: 4027 DESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGGRCARDLCS 4206
DE E C T CP C+N CI + ++C+ C +DE G +
Sbjct: 59 DEQ-EHLCHTPEPT--CPLHQFRCDNGH--CIEMGRVCNHVDDCSDNSDEKGCGINECLD 113
Query: 4207 ADRAGCSFKCHNSPNGPICSCPFGEQLVN-KTKCEPENECLDSSS-CSQRCKDEKHGFTC 4380
+ + C C ++ CSC G +L++ K C +EC +S CSQ+C++ + C
Sbjct: 114 SSISRCDHNCTDTITSFYCSCLPGYKLMSDKRSCVDIDECKESPQLCSQKCENVVGSYIC 173
Query: 4381 SCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGAIVE---NAIAL 4551
C GY + D ++C+ N++ I+ SNR YY + + ++ I++ N +AL
Sbjct: 174 KCAPGYIREPDGKSCRQNSNIEPYLIF-SNR---YYIRNLTTDGSSYSLILQGLGNVVAL 229
Query: 4552 AWDSLTDRIYWSDIREKKILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVDSSLN 4731
+D + R+YW D ++ I N TN I L E + +DWV LYW+D+ L+
Sbjct: 230 DFDRVEKRLYWIDAEKQIIERMFLNKTNRETIINHRLRRAESLDVDWVSTKLYWLDAILD 289
Query: 4732 TIEVANLEDPKQRTLLVH----QNV---SQPRGIAVDPRKGVMFWTDWGQNPCIERASMD 4890
+ V++LE ++ + H N PRGI + P++G ++WTDWG + I R MD
Sbjct: 290 CLFVSDLEGRHRKMIAQHCVDANNTFCFEHPRGIVLHPQRGHVYWTDWGVHAYIGRIGMD 349
Query: 4891 GTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHP 5070
GT++ +I+ TKI WPN I +DYT D +Y+AD+ L +I+F + +G R V S + HP
Sbjct: 350 GTNKSVIISTKIEWPNAITIDYTNDLLYWADAHLGYIEFSDLEGHHRHTVYDGS--LPHP 407
Query: 5071 HALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNP 5250
AL IFED ++++D + ++ KY +G+ +T K + HP QP++ +NP
Sbjct: 408 FALTIFEDTVFWTDWNTRTVEKGNKY-DGSGRVVLVNTTHKPFDIHVYHPYRQPIM-SNP 465
Query: 5251 CSTN--PCSHLCLLN-NKNTFTCKCP 5319
C TN CSHLCL+ FTC CP
Sbjct: 466 CGTNNGGCSHLCLIKAGGRGFTCACP 491
Score = 280 bits (715), Expect = 1e-72
Identities = 210/681 (30%), Positives = 297/681 (42%), Gaps = 29/681 (4%)
Frame = +1
Query: 169 DFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAEYQRC 348
DFRC + CI W C +++C CI C
Sbjct: 725 DFRCANHHCIPLRWKCDGTDDCGDNSDEENCVPRECSESEFRCADQ-----QCIPSRWVC 779
Query: 349 DNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCS 528
D DC D SDE+DC T C ++ F C G C + CDG+ DC D SDE +
Sbjct: 780 DQENDCGDNSDERDCEMKT--CHPEH-FQCTSGH-CVPKALACDGRADCLDASDESACPT 835
Query: 529 R--NHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEP-DTCEFKKCTANE-FQCKN 696
R N T C F C + CIQ W+CDG DC DGSDE C C + + F+C N
Sbjct: 836 RFPNGTYCPAAMFECKNHV-CIQSFWICDGENDCVDGSDEEIHLCFNIPCESPQRFRCDN 894
Query: 697 KRCQPRKFRCDYYDDCGDNSDEDE--CGEYR---CPPGKWNCPGTGHCIDQLKLCDGSKD 861
RC C+ DDCGD SDE E C + C ++ C G+CI Q +CD D
Sbjct: 895 SRCVYGHQLCNGVDDCGDGSDEKEEHCRKPTHKPCTDTEYKC-SNGNCISQHYVCDNVND 953
Query: 862 CADGADEQQCS---QNLCPSLGCQAGCHPSPHGGE-CTCPSGYKLDDRFHRTCSDINECA 1029
C D +DE C+ C C+ C GG C+C G+K +C DINEC
Sbjct: 954 CGDLSDETGCNLGDNRTCAENICEQNCTQLSSGGFICSCRPGFKPSTSDKNSCQDINECE 1013
Query: 1030 EFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARRE 1209
EFG C Q C N + + C C+ ++ +G C ++ + + L
Sbjct: 1014 EFGICPQSCRNSKGSYECFCVDGFKSMSTHYGE---------RCAADGSPPLLLLPEN-- 1062
Query: 1210 GLYRLNPKNPDEE--VKKLASGEFIYGIDFDY-----GDRKIFWTDRLAHSAFSA----- 1353
R+ N E + L E I ID+D+ G +++T S F A
Sbjct: 1063 --VRIRKYNTSSEKFSEYLEEEEHIQTIDYDWDPEHIGLSVVYYTVLAQGSQFGAIKRAY 1120
Query: 1354 -DVDDEGEISQIKK--LSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVL 1524
+ G + I++ L LK L+ P LAVDW+ +Y ++ S+RI+V++ DG R L
Sbjct: 1121 IPNFESGSNNPIREVDLGLKYLMQPDGLAVDWVGRHIYWSDAKSQRIEVATLDGRYRNWL 1180
Query: 1525 LADGLTLPLDIALDPLRGEMFFTNQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVD-ITAK 1701
+ L P LD +G+ Q K+E+A M+G +R LV+ + +G+ +D +
Sbjct: 1181 ITTQLDQPRSYVLDD-QGK-----QPKIESAWMNGEHRSVLVSENLGWPNGLSIDYLNDD 1234
Query: 1702 RVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEK 1881
RVYW D K D +E+I Y G DRR++ +N PF L +F+ LYW + V + K
Sbjct: 1235 RVYWSDSKEDVIEAIKYDGTDRRLI---INEAMKPFSLDIFEDKLYWVAKEKGEVWRQNK 1291
Query: 1882 FGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKD 2061
FG + K N + + +H + + NPC C +C+L
Sbjct: 1292 FGKENK--EKVLVVNPWLTQVRIFHQLR---------YKQSVSNPCKQV-CSHLCLLRPG 1339
Query: 2062 NGGFGVGYKCACPIGQKLVNG 2124
GY CACP G V G
Sbjct: 1340 ------GYSCACPQGSDFVTG 1354
Score = 226 bits (577), Expect = 1e-56
Identities = 156/537 (29%), Positives = 243/537 (45%), Gaps = 30/537 (5%)
Frame = +1
Query: 580 QCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSD 759
+C+++S+ CD DC D SDE C + C AN+F C+N RC PR F CD +DCGD SD
Sbjct: 1 RCVRQSFRCDRRNDCGDYSDERG-CSYPPCHANQFTCQNGRCIPRFFVCDEDNDCGDGSD 59
Query: 760 EDE----CGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLG--- 918
E E E CP ++ C GHCI+ ++C+ DC+D +DE+ C N C
Sbjct: 60 EQEHLCHTPEPTCPLHQFRC-DNGHCIEMGRVCNHVDDCSDNSDEKGCGINECLDSSISR 118
Query: 919 CQAGCHPSPHGGECTCPSGYKL-DDRFHRTCSDINECAEF-GYCDQLCANHRPGFTCSCL 1092
C C + C+C GYKL D+ R+C DI+EC E C Q C N + C C
Sbjct: 119 CDHNCTDTITSFYCSCLPGYKLMSDK--RSCVDIDECKESPQLCSQKCENVVGSYICKC- 175
Query: 1093 GDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKLASGE 1272
PG C N+ + L + R + L + G
Sbjct: 176 ----------APGYIREPDGKSCRQNSNIEPYLIFSNRYYIRNLTTDGSSYSLILQGLGN 225
Query: 1273 FIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQ---IKKLSLKSLVYPR-----CL 1428
+ +DFD +++++W +D E +I + + K + ++++ R L
Sbjct: 226 -VVALDFDRVEKRLYW------------IDAEKQIIERMFLNKTNRETIINHRLRRAESL 272
Query: 1429 AVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTL--------PLDIALDPLRGEM 1584
VDW++ LY +++ + VS +G R ++ + P I L P RG +
Sbjct: 273 DVDWVSTKLYWLDAILDCLFVSDLEGRHRKMIAQHCVDANNTFCFEHPRGIVLHPQRGHV 332
Query: 1585 FFTN---QLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQ 1755
++T+ + MDGTN+ +++T + I +D T +YW D + +E D +
Sbjct: 333 YWTDWGVHAYIGRIGMDGTNKSVIISTKIEWPNAITIDYTNDLLYWADAHLGYIEFSDLE 392
Query: 1756 GNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFP 1935
G+ R V G +PHPF L +F+ ++WTDW V + K+ +++ NT + P
Sbjct: 393 GHHRHTVYDGS--LPHPFALTIFEDTVFWTDWNTRTVEKGNKYDGSGRVVLVNTTHK--P 448
Query: 1936 MGISAYHPMAQPGPGQSECLAMKIENPC--TNADCEGMCILSKDNGGFGVGYKCACP 2100
I YHP QP + NPC N C +C++ G G+ CACP
Sbjct: 449 FDIHVYHPYRQP----------IMSNPCGTNNGGCSHLCLIKAG----GRGFTCACP 491
Score = 176 bits (446), Expect = 1e-41
Identities = 107/309 (34%), Positives = 142/309 (45%), Gaps = 13/309 (4%)
Frame = +1
Query: 145 ASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVS 324
AS C F+CN+G+CI W P C + + CD +T S
Sbjct: 632 ASRTCRPGQFKCNNGRCIPQSW---KCDVDNDCGDYSDEPIDECTTAAYNCDNHTEFSCK 688
Query: 325 ----CIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYD 492
CI ++ C+ DC + SDE+ C +V C F CA+ C + KCDG D
Sbjct: 689 TNYRCIPQWAVCNGFDDCRENSDEQGC--ESVPCHPSGDFRCAN-HHCIPLRWKCDGTDD 745
Query: 493 CRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCT 672
C D SDE++ R C + +FRCAD+ QCI WVCD DC D SDE D CE K C
Sbjct: 746 CGDNSDEENCVPRE---CSESEFRCADQ-QCIPSRWVCDQENDCGDNSDERD-CEMKTCH 800
Query: 673 ANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDEC------GEYRCPPGKWNCPGTGHCIDQ 834
FQC + C P+ CD DC D SDE C G Y CP + C CI
Sbjct: 801 PEHFQCTSGHCVPKALACDGRADCLDASDESACPTRFPNGTY-CPAAMFECK-NHVCIQS 858
Query: 835 LKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGEC---TCPSGYKLDDRFHRT 1005
+CDG DC DG+DE+ +LC ++ C+ SP C C G H+
Sbjct: 859 FWICDGENDCVDGSDEE---IHLCFNIPCE-----SPQRFRCDNSRCVYG-------HQL 903
Query: 1006 CSDINECAE 1032
C+ +++C +
Sbjct: 904 CNGVDDCGD 912
Score = 156 bits (395), Expect = 1e-35
Identities = 86/265 (32%), Positives = 126/265 (47%), Gaps = 5/265 (1%)
Frame = +1
Query: 148 SSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPG--CKSDQWQCDTYTWHSV 321
S C N+++C + +CI W C+ Q++C+ +
Sbjct: 592 SHECESNEWQCANKRCIPQSWQCDSVNDCLDNSDEDTSHCASRTCRPGQFKCN-----NG 646
Query: 322 SCIAEYQRCDNITDCADGSDEK--DCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDC 495
CI + +CD DC D SDE +C + +C + F C +C C+G DC
Sbjct: 647 RCIPQSWKCDVDNDCGDYSDEPIDECTTAAYNCDNHTEFSCKTNYRCIPQWAVCNGFDDC 706
Query: 496 RDLSDEKDSCSRNHTACFQY-QFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCT 672
R+ SDE+ S C FRCA+ CI W CDG+ DC D SDE + C ++C+
Sbjct: 707 RENSDEQGCES---VPCHPSGDFRCANH-HCIPLRWKCDGTDDCGDNSDE-ENCVPRECS 761
Query: 673 ANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDG 852
+EF+C +++C P ++ CD +DCGDNSDE +C C P + C +GHC+ + CDG
Sbjct: 762 ESEFRCADQQCIPSRWVCDQENDCGDNSDERDCEMKTCHPEHFQCT-SGHCVPKALACDG 820
Query: 853 SKDCADGADEQQCSQNLCPSLGCQA 927
DC D +DE C C A
Sbjct: 821 RADCLDASDESACPTRFPNGTYCPA 845
Score = 152 bits (383), Expect = 3e-34
Identities = 102/295 (34%), Positives = 138/295 (46%), Gaps = 17/295 (5%)
Frame = +1
Query: 268 PGCKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDEKD-CPASTVDCSSQNVFMCAD 444
P C S Q+ C ++ CI + +CD DC+DGSDE D CP F C D
Sbjct: 507 PMCSSQQFLCG----NNEKCIPIWWKCDGQKDCSDGSDEPDLCPHRFCRLGQ---FQCRD 559
Query: 445 GRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTA---CFQYQFRCADKTQCIQKSWVCDGS 615
G C C+ + DC D SDE +H C +++CA+K +CI +SW CD
Sbjct: 560 G-NCTSPQALCNARQDCADGSDEDRVLCEHHRVSHECESNEWQCANK-RCIPQSWQCDSV 617
Query: 616 KDCADGSDEPDT-CEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDE--DEC--GEY 780
DC D SDE + C + C +F+C N RC P+ ++CD +DCGD SDE DEC Y
Sbjct: 618 NDCLDNSDEDTSHCASRTCRPGQFKCNNGRCIPQSWKCDVDNDCGDYSDEPIDECTTAAY 677
Query: 781 RCP-PGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLG---CQAGCHPSPH 948
C +++C CI Q +C+G DC + +DEQ C C G C A H P
Sbjct: 678 NCDNHTEFSCKTNYRCIPQWAVCNGFDDCRENSDEQGCESVPCHPSGDFRC-ANHHCIPL 736
Query: 949 GGEC----TCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDC 1101
+C C ++ R CS+ +EF DQ C R + C DC
Sbjct: 737 RWKCDGTDDCGDNSDEENCVPRECSE----SEFRCADQQCIPSR--WVCDQENDC 785
Score = 140 bits (354), Expect = 7e-31
Identities = 154/688 (22%), Positives = 245/688 (35%), Gaps = 23/688 (3%)
Frame = +1
Query: 11665 KCIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADE 11844
+C+ S CD C D DE C+ C C +G CI CD DC + +DE
Sbjct: 1 RCVRQSFRCDRRNDCGDYSDERGCSYPPCHANQFTCQNGRCIPRFFVCDEDNDCGDGSDE 60
Query: 11845 L-HCEDVSRRTCSPFEFECANSVCIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFR 12021
H TC +F C N CI
Sbjct: 61 QEHLCHTPEPTCPLHQFRCDNGHCI----------------------------------- 85
Query: 12022 CAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSFSEYGDCSSDQFKCANGKCVNGTVA 12201
+ ++CN +DC N SD+ C +C++ +++
Sbjct: 86 --------EMGRVCNHVDDCSDN--------------------SDEKGCGINECLDSSIS 117
Query: 12202 -CDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQS 12378
CD +C D C SC K C D+ D + PQ
Sbjct: 118 RCDH--NCTDTITSFYC-------SCLPGYKLMSDKRSCVDI---------DECKESPQ- 158
Query: 12379 PKECIDIDECAGNNTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMI 12558
C+Q C N GSY+C+C Y + GK CR + +I
Sbjct: 159 --------------LCSQKCENVVGSYICKCAPGY-----IREPDGKSCRQNSNIEPYLI 199
Query: 12559 GADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERTIYRSAIAN 12738
++ ++ +L G++ R +YWID ++ I R +
Sbjct: 200 FSNRYYIR-NLTTDGSSYSLILQGLGNVVALDFDRVEKR---LYWIDAEKQIIERMFLNK 255
Query: 12739 GNQS-------HEGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAVSENIENGLVTARKKR 12897
N+ + LDVD+ V +D LF+ + L +K
Sbjct: 256 TNRETIINHRLRRAESLDVDW----VSTKLYWLDAILDCLFV--------SDLEGRHRKM 303
Query: 12898 MSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECA 13077
+++ + N F F + P ++ P G + ++D G+HA I
Sbjct: 304 IAQHCVDANNTFCF-----------------EHPRGIVLHPQRGHVYWTDWGVHAYIGRI 346
Query: 13078 DMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHI 13257
MDGT++ +I+ + P ++ ID + +YW D ++ +++G R T V+D +
Sbjct: 347 GMDGTNKSVIISTKIEWPNAITIDY-TNDLLYWADAHLGYIEFSDLEGHHRHT-VYDGSL 404
Query: 13258 --PYAVDVFENHIYWLSRESKTLYVQDKF-GRGRVSVLASDLEDGHTVRVSQKYAKDTQR 13428
P+A+ +FE+ ++W ++T+ +K+ G GRV VL + + V Y +
Sbjct: 405 PHPFALTIFEDTVFWTDWNTRTVEKGNKYDGSGRV-VLVNTTHKPFDIHVYHPYRQPIMS 463
Query: 13429 TVSGCERAQCSHLC-VSLPSTGFACLCPDGIVPQLDGSCATQHVEALTMP----KQCKCT 13593
G CSHLC + GF C CPD D L MP +Q C
Sbjct: 464 NPCGTNNGGCSHLCLIKAGGRGFTCACPD------DFQTVQLRDRTLCMPMCSSQQFLCG 517
Query: 13594 NGGKC-----RLDGSCECT-SDFEGDQC 13659
N KC + DG +C+ E D C
Sbjct: 518 NNEKCIPIWWKCDGQKDCSDGSDEPDLC 545
Score = 95.5 bits (236), Expect = 3e-17
Identities = 77/291 (26%), Positives = 131/291 (44%), Gaps = 17/291 (5%)
Frame = +1
Query: 6472 ITGVDYDYESKTI------YVAEASGINKG------ITAYTIGESSP-RAVIRDSIGSLT 6612
I +DYD++ + I Y A G G I + G ++P R V +
Sbjct: 1085 IQTIDYDWDPEHIGLSVVYYTVLAQGSQFGAIKRAYIPNFESGSNNPIREVDLGLKYLMQ 1144
Query: 6613 IKSLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYW 6792
LA+DW+ ++Y+ DA+ IEV+ LDG YR L+TT+ + P S +D
Sbjct: 1145 PDGLAVDWVGRHIYW--SDAKSQRIEVATLDGRYRNWLITTQLDQPRSYVLD-------- 1194
Query: 6793 ADQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVD-VASKMIYWSDAKMDGIYRVRSTG 6969
DQG++P I+ ++++G R V+VS + P L +D + +YWSD+K D I ++ G
Sbjct: 1195 -DQGKQPKIESAWMNGEHRSVLVSENLGWPNGLSIDYLNDDRVYWSDSKEDVIEAIKYDG 1253
Query: 6970 GTPELVRSDIASAAGVALHGQNMYWTDNRLEKLFRAT--SKPNQTSLLLSPTTVAASLKD 7143
L+ ++ + + +YW +++R K N+ +L+ +
Sbjct: 1254 TDRRLIINEAMKPFSLDIFEDKLYWVAKEKGEVWRQNKFGKENKEKVLVVNPWLT----- 1308
Query: 7144 IGDVAVFSS-NNQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCARG 7293
V +F + S+PC K C+ LC PG +C+C +G
Sbjct: 1309 --QVRIFHQLRYKQSVSNPC-------KQVCSHLCLLRPGGY--SCACPQG 1348
Score = 93.2 bits (230), Expect = 2e-16
Identities = 80/337 (23%), Positives = 149/337 (43%), Gaps = 13/337 (3%)
Frame = +1
Query: 6313 CTCANGYVK--DGQTSCKLFD--ESFVIVATKTKVIGYPIDETQSKGVAMEPIGGLSITG 6480
C CA GY++ DG+ SC+ E ++I + + + D + S + ++ +G ++
Sbjct: 173 CKCAPGYIREPDGK-SCRQNSNIEPYLIFSNRYYIRNLTTDGS-SYSLILQGLG--NVVA 228
Query: 6481 VDYDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINYNMYFI 6660
+D+D K +Y +A + I + +++ +I + +SL +DW++ +Y++
Sbjct: 229 LDFDRVEKRLYWIDAE--KQIIERMFLNKTNRETIINHRLRRA--ESLDVDWVSTKLYWL 284
Query: 6661 NHDAERTNIEVSKLDGTYRKILL--------TTKTETPSSIAVDPVSRYLYWADQGQKPT 6816
DA + VS L+G +RK++ T E P I + P ++YW D G
Sbjct: 285 --DAILDCLFVSDLEGRHRKMIAQHCVDANNTFCFEHPRGIVLHPQRGHVYWTDWGVHAY 342
Query: 6817 IQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPELV-RS 6993
I R +DG+ + VI+S+ I P + +D + ++YW+DA + I G V
Sbjct: 343 IGRIGMDGTNKSVIISTKIEWPNAITIDYTNDLLYWADAHLGYIEFSDLEGHHRHTVYDG 402
Query: 6994 DIASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSN 7173
+ + + ++WTD + + ++L TT D+ V+
Sbjct: 403 SLPHPFALTIFEDTVFWTDWNTRTVEKGNKYDGSGRVVLVNTTHKPF-----DIHVYHPY 457
Query: 7174 NQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSC 7284
QP S+PC C+ LC G + TC+C
Sbjct: 458 RQPIMSNPC----GTNNGGCSHLCLIKAGGRGFTCAC 490
Score = 83.2 bits (204), Expect = 2e-13
Identities = 85/367 (23%), Positives = 146/367 (39%), Gaps = 9/367 (2%)
Frame = +1
Query: 5251 CSTNP--CSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDA--KPFLVIIQKTNVFGIEM 5418
C +P CS C N ++ CKC G + GK C ++ +P+L+ + + +
Sbjct: 153 CKESPQLCSQKCE-NVVGSYICKCAPGYIREPDGKSCRQNSNIEPYLIFSNRYYIRNLTT 211
Query: 5419 NSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRST 5598
+ +S + L GLGN +D + + ++ ++ I R
Sbjct: 212 DGSSYS--------LILQGLGNVVALDFDRVEKRLYWID-----------AEKQIIERMF 252
Query: 5599 VNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVILS--ND 5772
+N N+ + + + A L DW L + I + + +G+ + + +
Sbjct: 253 LNKTNRETIINHRLRR-AESLDVDWVSTKLYWLDAILDCLFVSDLEGRHRKMIAQHCVDA 311
Query: 5773 QSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIA 5952
+ +G+V+W D G A + R G+DG+N VI S + + I
Sbjct: 312 NNTFCFEHPRGIVLHPQRGHVYWTDWG---VHAYIGRIGMDGTNKSVIISTKIEWPNAIT 368
Query: 5953 IDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAFDSIE 6132
ID TN +Y+++A G I +G RH V P L + D +F+ D ++E
Sbjct: 369 IDYTNDLLYWADAHLGYIEFSDLEGHHRHTVYDGSLPHPFALTIFEDTVFWTDWNTRTVE 428
Query: 6133 VATI---NGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHINNGNCDHICIPLMFA 6303
+G TH D+ + QP S +PC NNG C H+C+ +
Sbjct: 429 KGNKYDGSGRVVLVNTTHKPFDIHVYHPYR--QPIMS---NPCGTNNGGCSHLCL-IKAG 482
Query: 6304 QRTCTCA 6324
R TCA
Sbjct: 483 GRGFTCA 489
Score = 81.6 bits (200), Expect = 5e-13
Identities = 43/110 (39%), Positives = 60/110 (54%), Gaps = 4/110 (3%)
Frame = +1
Query: 11536 KCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSD 11715
+C+ + + CD NDCGD SDE G + PC ++F C +G+CIP VCD C D
Sbjct: 1 RCVRQSFRCDRRNDCGDYSDER----GCSYPPCHANQFTCQNGRCIPRFFVCDEDNDCGD 56
Query: 11716 GLDESQ--C-TLRRCLPGHR-QCDDGTCIAEHKWCDRKKDCPNAADELHC 11853
G DE + C T P H+ +CD+G CI + C+ DC + +DE C
Sbjct: 57 GSDEQEHLCHTPEPTCPLHQFRCDNGHCIEMGRVCNHVDDCSDNSDEKGC 106
Score = 81.3 bits (199), Expect = 7e-13
Identities = 57/194 (29%), Positives = 80/194 (40%), Gaps = 19/194 (9%)
Frame = +1
Query: 8533 RCIDSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQV 8712
RC+ + +C+ +DCGD SDE C S C F C NG CI + VCD NDC D
Sbjct: 1 RCVRQSFRCDRRNDCGDYSDERGC-SYPPCHANQFTCQNGRCIPRFFVCDEDNDCGDG-- 57
Query: 8713 SDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQH 8892
SDE C C + RC N + CI+ +C+ DDC D +DE C +C
Sbjct: 58 SDEQEHLCHTPEPTCPLHQFRCDNGH-CIEMGRVCNHVDDCSDNSDEKG--CGINECLDS 114
Query: 8893 YV-RC----------------PSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKI-- 9015
+ RC P + + + C ++C + C + G I
Sbjct: 115 SISRCDHNCTDTITSFYCSCLPGYKLMSDKRSCVDIDECKESPQLCSQKCENVVGSYICK 174
Query: 9016 CVGDYLFQCDNLKC 9057
C Y+ + D C
Sbjct: 175 CAPGYIREPDGKSC 188
Score = 77.4 bits (189), Expect = 9e-12
Identities = 57/196 (29%), Positives = 80/196 (40%), Gaps = 28/196 (14%)
Frame = +1
Query: 8413 CILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHIDDCGDGSD 8592
C+ CD + DC D SDE C+ C + C N RCI C+ +DCGDGSD
Sbjct: 2 CVRQSFRCDRRNDCGDYSDERG--CSYPPCHANQFTCQNGRCIPRFFVCDEDNDCGDGSD 59
Query: 8593 ELD--CPS-AVACAEGTFPCSNGHCINQTKVCDGHNDCHD---------EQVSDESLATC 8736
E + C + C F C NGHCI +VC+ +DC D + D S++ C
Sbjct: 60 EQEHLCHTPEPTCPLHQFRCDNGHCIEMGRVCNHVDDCSDNSDEKGCGINECLDSSISRC 119
Query: 8737 ----------------PGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFC 8868
PG + K C + + C + LC + EN +
Sbjct: 120 DHNCTDTITSFYCSCLPGYKL--MSDKRSCVDIDECKESPQLC-------SQKCENVVGS 170
Query: 8869 MNQQCAQHYVRCPSGR 8916
+CA Y+R P G+
Sbjct: 171 YICKCAPGYIREPDGK 186
Score = 73.9 bits (180), Expect = 1e-10
Identities = 33/65 (50%), Positives = 41/65 (62%), Gaps = 2/65 (3%)
Frame = +1
Query: 3544 CGNATCAANQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERC--PPVQCSALQFRCANGR 3717
C C ANQF+C NGRCIP +++CD DNDC DG+DE + C P C QFRC NG
Sbjct: 24 CSYPPCHANQFTCQNGRCIPRFFVCDEDNDCGDGSDEQEHLCHTPEPTCPLHQFRCDNG- 82
Query: 3718 QCVPL 3732
C+ +
Sbjct: 83 HCIEM 87
Score = 73.2 bits (178), Expect = 2e-10
Identities = 54/181 (29%), Positives = 75/181 (40%), Gaps = 5/181 (2%)
Frame = +1
Query: 8794 CIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWD 8973
C++ + CD +DCGD +DE C C + C +GRCIP + CD DNDC DG D
Sbjct: 2 CVRQSFRCDRRNDCGDYSDERG--CSYPPCHANQFTCQNGRCIPRFFVCDEDNDCGDGSD 59
Query: 8974 ETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTD 9153
E C + C + F+CDN CI + GCG C D
Sbjct: 60 EQEHLC--HTPEPTC-PLHQFRCDNGHCIEMGRVCNHVDDCSDNS---DEKGCGINECLD 113
Query: 9154 QEF-HCTSNAKLAQPKY--ECIPRAWLCDGDVTCAGGED--ESTELCKTEKKECNKGEFR 9318
C N + C+P L +C ++ ES +LC ++K E G +
Sbjct: 114 SSISRCDHNCTDTITSFYCSCLPGYKLMSDKRSCVDIDECKESPQLC-SQKCENVVGSYI 172
Query: 9319 C 9321
C
Sbjct: 173 C 173
Score = 65.5 bits (158), Expect = 4e-08
Identities = 93/396 (23%), Positives = 161/396 (40%), Gaps = 27/396 (6%)
Frame = +1
Query: 5266 CSHLCLLNNKNTFTCKCPMGEKLDAS--GKKCIDDAKPFLVIIQKTNVFGIEMNSASEKE 5439
C C N+K ++ C C G K ++ G++C D P L+++ + NV + N++SEK
Sbjct: 1018 CPQSCR-NSKGSYECFCVDGFKSMSTHYGERCAADGSPPLLLLPE-NVRIRKYNTSSEKF 1075
Query: 5440 TPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTV-----N 5604
+ L + + +D + LS + + LAQ + AI R+ +
Sbjct: 1076 SEYLEEEEHIQTIDYDWDPEHIGLSVVYYTV--------LAQGSQFGAIKRAYIPNFESG 1127
Query: 5605 GGNKTKMFSSAV-----PDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVILSN 5769
N + + PD L DW GR++ + +Q IE+ G+ YR+ +++
Sbjct: 1128 SNNPIREVDLGLKYLMQPDG---LAVDWVGRHIYWSDAKSQRIEVATLDGR-YRNWLITT 1183
Query: 5770 DQSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHI 5949
+ YV LD G K+ A ++G + V+ S +L + +
Sbjct: 1184 QLDQP-------------RSYV--LDDQG--KQPKIESAWMNGEHRSVLVSENLGWPNGL 1226
Query: 5950 AIDTTNT-RVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAFDS 6126
+ID N RVY+S++K I ++ YDG DR ++++ +P L + D+L++
Sbjct: 1227 SIDYLNDDRVYWSDSKEDVIEAIKYDGTDRRLIINE-AMKPFSLDIFEDKLYW------- 1278
Query: 6127 IEVATINGDSQPPQWTHFKKDVENLANIKALQP------------RASSSGHPCHINNGN 6270
VA G+ W K EN + + P S +PC
Sbjct: 1279 --VAKEKGE----VWRQNKFGKENKEKVLVVNPWLTQVRIFHQLRYKQSVSNPC---KQV 1329
Query: 6271 CDHICIPLMFAQRTCTCANG--YVKDGQTSCKLFDE 6372
C H+C+ L +C C G +V C E
Sbjct: 1330 CSHLCL-LRPGGYSCACPQGSDFVTGSTVQCDAASE 1364
Score = 60.8 bits (146), Expect = 9e-07
Identities = 64/288 (22%), Positives = 91/288 (31%)
Frame = +1
Query: 10918 KCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXX 11097
+C+ + + CD DC D SDE G C C +F C N
Sbjct: 1 RCVRQSFRCDRRNDCGDYSDERG---CSYPPCHANQFTCQN------------------- 38
Query: 11098 XXEQNCDKACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEADTLCMSAERNCTAEEFR 11277
GRCIPR F SDE + LC + E C +FR
Sbjct: 39 --------------------GRCIPRFFVCDEDNDCGDGSDEQEHLCHTPEPTCPLHQFR 78
Query: 11278 CNNNKCIAKAWRXXXXXXXXXXXXETPECAQIECKKGWTRCSSSYRCIPNWAFCNGQDDC 11457
C+N CI E ++ CN DDC
Sbjct: 79 CDNGHCI--------------------EMGRV---------------------CNHVDDC 97
Query: 11458 RDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCS 11637
DNSDE C D RC +++C D SC + S
Sbjct: 98 SDNSDEKGCGINECLDSSISRC---------------DHNCTDTITSFYCSCLPGYKLMS 142
Query: 11638 ESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQCDDG 11781
+ + +C ++C + +C + + C +C PG+ + DG
Sbjct: 143 DKRSCVDIDECKESPQLC--SQKCENVVGSYIC---KCAPGYIREPDG 185
Score = 55.1 bits (131), Expect = 5e-05
Identities = 47/178 (26%), Positives = 68/178 (37%), Gaps = 15/178 (8%)
Frame = +1
Query: 271 GCKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDEKD--CPASTVDCSSQNVFMCAD 444
GC + +T + CI + CD DC DGSDE++ C C F C +
Sbjct: 23 GCSYPPCHANQFTCQNGRCIPRFFVCDEDNDCGDGSDEQEHLCHTPEPTCPLHQ-FRCDN 81
Query: 445 GRQCFDVSKKCDGKYDCRDLSDEKDSCSRNH---TACFQYQFRCADK-----TQCIQKSW 600
G C ++ + C+ DC D SDEK C N ++ + C D C+
Sbjct: 82 G-HCIEMGRVCNHVDDCSDNSDEK-GCGINECLDSSISRCDHNCTDTITSFYCSCLPGYK 139
Query: 601 VCDGSKDCAD---GSDEPDTCEFKKC--TANEFQCKNKRCQPRKFRCDYYDDCGDNSD 759
+ + C D + P C +KC + CK C P R C NS+
Sbjct: 140 LMSDKRSCVDIDECKESPQLCS-QKCENVVGSYICK---CAPGYIREPDGKSCRQNSN 193
Score = 54.3 bits (129), Expect = 9e-05
Identities = 40/154 (25%), Positives = 56/154 (35%), Gaps = 2/154 (1%)
Frame = +1
Query: 3199 RCIPKEWKCDGENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKKCIPAQXXXXXXXX 3378
RC+ + ++CD NDC D SD E+G C +
Sbjct: 1 RCVRQSFRCDRRNDCGDYSD---ERG--CSY----------------------------- 26
Query: 3379 XXXXXXXXVKYCKDGQKPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNA- 3555
P C A +F C N RCIP + E+ +C
Sbjct: 27 -----------------PPCHANQFTCQNGRCIPRFFVCDEDNDCGDGSDEQEHLCHTPE 69
Query: 3556 -TCAANQFSCANGRCIPIYWLCDGDNDCYDGTDE 3654
TC +QF C NG CI + +C+ +DC D +DE
Sbjct: 70 PTCPLHQFRCDNGHCIEMGRVCNHVDDCSDNSDE 103
Score = 51.6 bits (122), Expect = 6e-04
Identities = 49/181 (27%), Positives = 74/181 (40%), Gaps = 7/181 (3%)
Frame = +1
Query: 157 CNENDFRCNDGKCIR----TEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVS 324
C+ N F C +G+CI + P P C Q++CD +
Sbjct: 29 CHANQFTCQNGRCIPRFFVCDEDNDCGDGSDEQEHLCHTPEPTCPLHQFRCD-----NGH 83
Query: 325 CIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFD--VSKKCDGKYDCR 498
CI + C+++ DC+D SDEK C + +C ++ C C D S C +
Sbjct: 84 CIEMGRVCNHVDDCSDNSDEKGCGIN--ECLDSSISRC--DHNCTDTITSFYCSCLPGYK 139
Query: 499 DLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADG-SDEPDTCEFKKCTA 675
+SD K SC + C + C+ K + + S++C CA G EPD K C
Sbjct: 140 LMSD-KRSCV-DIDECKESPQLCSQKCENVVGSYIC----KCAPGYIREPDG---KSCRQ 190
Query: 676 N 678
N
Sbjct: 191 N 191
Score = 50.4 bits (119), Expect = 0.001
Identities = 31/100 (31%), Positives = 44/100 (44%), Gaps = 23/100 (23%)
Frame = +1
Query: 3085 RQGFMINKENNHSCQKDPAEKIEQLCSSNSTQFQCKNGRCIPKEWKCDGENDCLDESDEI 3264
RQ F ++ N+ D C +N QF C+NGRCIP+ + CD +NDC D SDE
Sbjct: 4 RQSFRCDRRNDCGDYSDERGCSYPPCHAN--QFTCQNGRCIPRFFVCDEDNDCGDGSDEQ 61
Query: 3265 D-----------------------EKGDKCFHETECAENT 3315
+ E G C H +C++N+
Sbjct: 62 EHLCHTPEPTCPLHQFRCDNGHCIEMGRVCNHVDDCSDNS 101
Score = 44.3 bits (103), Expect = 0.089
Identities = 28/97 (28%), Positives = 40/97 (40%), Gaps = 2/97 (2%)
Frame = +1
Query: 8362 PAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCI 8541
P C P + F+C +G CI +G C+ DC+D SDE C C + + C
Sbjct: 68 PEPTC-PLHQFRCDNGHCIEMGRVCNHVDDCSDNSDEKG--CGINECLDSSISRCDHNCT 124
Query: 8542 DSAKK--CNHIDDCGDGSDELDCPSAVACAEGTFPCS 8646
D+ C+ + SD+ C C E CS
Sbjct: 125 DTITSFYCSCLPGYKLMSDKRSCVDIDECKESPQLCS 161
Score = 38.5 bits (88), Expect = 4.9
Identities = 28/102 (27%), Positives = 41/102 (39%), Gaps = 13/102 (12%)
Frame = +1
Query: 3082 CRQGFMINKENNHSCQKDPAEKIEQLCSSNST-----QFQCKNGRCIPKEWKCDGENDCL 3246
C F + E+N D +++ E LC + QF+C NG CI C+ +DC
Sbjct: 41 CIPRFFVCDEDNDC--GDGSDEQEHLCHTPEPTCPLHQFRCDNGHCIEMGRVCNHVDDCS 98
Query: 3247 DESDE--------IDEKGDKCFHETECAENTIKCRNTKKCIP 3348
D SDE +D +C H + C C+P
Sbjct: 99 DNSDEKGCGINECLDSSISRCDHNCTDTITSFYC----SCLP 136
>gi|34853954|ref|XP_231214.2| similar to low density lipoprotein
receptor related protein LRP1B/LRP-DIT [Rattus norvegicus]
Length = 2281
Score = 876 bits (2263), Expect = 0.0
Identities = 627/2094 (29%), Positives = 912/2094 (42%), Gaps = 100/2094 (4%)
Frame = +1
Query: 7681 EHLSTIASGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESI 7860
E + T++ D + LA+D C L+FW T+ P I R+ L G + V+VS I
Sbjct: 64 EAVITMSEDDHPHVLALDECQNLMFW------TNWNEQHPSIMRATLTGKNAHVVVSTDI 117
Query: 7861 SLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGYRAK--SLDIWDRWLYMSD 8034
P + +D R +K+Y++D + IE +YDG R VI SL ++D +++ SD
Sbjct: 118 LTPNGLTIDHRAEKLYFSDGSLGKIERCEYDGSQRHVIVKSGPGTFLSLAVYDNYIFWSD 177
Query: 8035 PLSNGVFRIDKESGSGLENVVSDRRIPGA-LRVFASESDVRTRNQVCNALTSQLCKTDNG 8211
+ R +K +G + + SD IP + + A +D N+ C NG
Sbjct: 178 WGRRAILRSNKYTGGETKVLRSD--IPHQPMGIIAVANDT-------NSCELSPCALLNG 228
Query: 8212 GCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSEPAKECLPPYN 8391
GC LC + D +V CSC L+ +CV + S+ E
Sbjct: 229 GCHDLCLLTPD------GRVNCSCRGDRTLLAS------NRCVTKNSSCNIYSE------ 270
Query: 8392 FQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHID 8571
F+CG+G C+ TCD P C D SDE YC RSC + C NRRC+ K C+ +
Sbjct: 271 FECGNGDCVDYVLTCDGIPHCKDKSDEKLLYCENRSCRSGFKPCYNRRCVPHGKLCDGTN 330
Query: 8572 DCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPGLPI 8751
DCGDGSDELDC C+ F C++G CI ++ C+ + DC D SDE
Sbjct: 331 DCGDGSDELDC-KVSTCSTVEFRCTDGTCIPRSARCNQNMDCSD--ASDEKGCN----NT 383
Query: 8752 DCR-----GVK----VRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQ-QCAQHYVR 8901
DC GVK +RC +T++C+ P+ +CDG +DCGD +DE + N+ +C ++Y
Sbjct: 384 DCTHFYKLGVKSTGFIRCNSTSLCVLPSWICDGSNDCGDYSDELKCPVQNKHKCEENYFG 443
Query: 8902 CPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXX 9081
CPSGRCI TW CDG DC DG DE H + + + + F C KCIS+ +I
Sbjct: 444 CPSGRCILNTWVCDGQKDCEDGLDELHCDSSCSWNQ--------FACSVHKCISKHWI-C 494
Query: 9082 XXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGED 9261
S + CG TC F C Q + C+P+ WLCDG+ C G D
Sbjct: 495 DGEDDCGDGLDESDNICGAVTCAADMFSC-------QSSHACVPQHWLCDGERDCPDGSD 547
Query: 9262 ESTELCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANC------------ 9405
E + C++ F C N+ CI + CD D+DC DGSDE C
Sbjct: 548 ELSSAGCAPNNTCDENAFMCHNKVCIPKQFVCDHDDDCGDGSDEFLECGTSCSCRDRLQT 607
Query: 9406 ----------------TYSSCQPDFFQCANHKCVPNS-WKCDGNDDCEDGSDEKDCPKNS 9534
Y C P+ F+CA+ +C+ N+ W+CDG+ DC D SDE P N
Sbjct: 608 GCYGSLTSTVQYDKFFRYRQCGPEEFRCADGRCLVNTLWQCDGDFDCPDSSDE--APINP 665
Query: 9535 ASAQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQK 9714
C++ F C +G CI +CD DC D S+E C I+EC + C Q
Sbjct: 666 RCTSAEHSCNSSFFMCKNGRCIPRDGLCDNRDDCGDGSEEPK-CHINECLSKKISGCSQD 724
Query: 9715 CMDMKIGYKCDCFEGFAIDISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQL 9894
C D+ I YKC C+ GF + D K+C +++EC G CSQ+C + G+YKC C +GY+
Sbjct: 725 CQDLPISYKCKCWPGFQLK-DDGKTCVDIDECSTGFP-CSQQCINTYGTYKCRCTEGYET 782
Query: 9895 SSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYELAAQ-GFDNVVSLDIDLTEKKAY 10071
D+ + R +P + + K + N E A++ G +NV+++D D E+ Y
Sbjct: 783 QPDNQNGCR---KPSKVIDVFQEAVELKANPCLNIREAASRHGLNNVIAIDFDYREEFIY 839
Query: 10072 LIDQGK---LRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQE-RS 10239
ID + R+ R+ L+ D V+ G + VGR LY ++ E
Sbjct: 840 WIDSSRPNGSRINRMCLNGSDI-----------KVWWRRGDELG-VGRNLYWIDCCEYPH 887
Query: 10240 IRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPI 10419
I +DG +I +I +P A+ + L+ W+ + +I +DGS
Sbjct: 888 IGRVGMDGTNQSVVIETKISRPMALTIDYVNHRLY---WADENHIEFSNMDGSHR----- 939
Query: 10420 FKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVVF 10599
K+ D+ P IA+ F D ++W
Sbjct: 940 HKVPNQDI--PGVIALTLFEDYIYW----------------------------------- 962
Query: 10600 DDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGC 10779
D + + R K +G + L + D+++ H RQP P
Sbjct: 963 ------TDGKTKSLSRVHKTSGADRLSLIYSWHAITDIQVYHSYRQPDGP---------- 1006
Query: 10780 SHLCLIGAGGNGYTCSCPDQFVLLSDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPD 10959
G +TC+CP F L +D +TC NCT QF C D KCIP W CD D
Sbjct: 1007 ---------GKTHTCACPTNFYLAADNRTCLSNCTASQFRCKTD--KCIPFWWKCDTVDD 1055
Query: 10960 CRDGSDEPGESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXXEQNC-------- 11115
C DGSDEP + C + C G FQC C P I E NC
Sbjct: 1056 CGDGSDEPDD--CPEFKCQPGRFQCGTGLCALPAFICDGENDCGDNSDELNCGQFKCTKN 1113
Query: 11116 --------------------------DKACDPWMFKCAATGRCIPRRFTXXXXXXXXXRS 11217
+ +C P F+C T CI + + S
Sbjct: 1114 KKCIPVNLRCNGQDDCGDEEDERDCPENSCSPDYFQCKTTKHCISKLWVCDEDPDCADAS 1173
Query: 11218 DEADTLCMSAERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXETPECAQIECKKGWTR 11397
DEA+ ++ C EF+C NN CI WR E C C
Sbjct: 1174 DEAN----CDKKTCGPHEFQCKNNNCIPDHWRCDSQNDCSDNSDE-ENCKPQTCTLRDFL 1228
Query: 11398 CSSSYRCIPNWAFCNGQDDCRDNSDE------DKQRCPTCDDVGEFRCATSGKCIPRRWM 11559
CS+ C+ + +C+G+ DC D SDE K+ C T +F+C ++G+C+ +W
Sbjct: 1229 CSNG-DCVSSRFWCDGEFDCADGSDEVGISVNAKKNCETSCSKDQFQC-SNGQCLSAKWK 1286
Query: 11560 CDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCT 11739
CD DC DE +C CS SE+ C G C+ S C+G C DG DE C
Sbjct: 1287 CDGHEDCKYGEDE--KNCEPAFPVCSSSEYMCASGGCLSASLKCNGETDCVDGSDEMDC- 1343
Query: 11740 LRRCLPGHRQC-DDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFECANSVCI 11916
+ C QC + CI CD DC + +DE +C C EF C NS+C
Sbjct: 1344 VTECKEDQFQCRNKAYCIPIRWLCDGIYDCVDGSDEENC-GRGGSICRADEFLCNNSLCK 1402
Query: 11917 PRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDF 12096
++ SDE C C P +RC + R+CL + ++CNG NDCG N
Sbjct: 1403 LHFWVCDGEDDCGDNSDEVPDMCVKFLCPPTRPYRCRNDRICLQLEKMCNGINDCGDNS- 1461
Query: 12097 SDEHLSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSC 12276
+EH S SF C D+F C N C+ + CD DDCGD SDE GC + + +C
Sbjct: 1462 DEEHCSGTLSFKS-EPCKKDEFTCNNRNCIPMELQCDGLDDCGDGSDEQGCMQTPTQHTC 1520
Query: 12277 EAFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGS 12456
E GN G C +R +C C+ GF+ + + +EC D++EC C+Q CLNT+GS
Sbjct: 1521 ENNGNPCGDDAYCNQIRTSVFCRCKPGFQRNIKG-RECADLNECLVFGICSQHCLNTRGS 1579
Query: 12457 YLCRCHEDYENNVVVGSMTGKDCRAKGDAANVM-IGADDSLVQLSLHGSGTNRHXXXXXX 12633
Y C C ++++ C AKG + I D ++ + + H
Sbjct: 1580 YKCVCDQNFQEK-------NNSCIAKGSEDQALYIANDTDILGFVYPFNYSGSHQQISHV 1632
Query: 12634 XXXXXXXXXXXXPRKELMYWID--GSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTA 12807
++ ++ W Y A + + +F P
Sbjct: 1633 EHNSRITGMDVYYQRNVIVWSTQFNPGGIFYTMIDAREKRQANSGLICPEFKR----PRD 1688
Query: 12808 IAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGH 12987
IAVD+ TGN++ S T + I N G + +G +++
Sbjct: 1689 IAVDWVTGNVYWTDHSRMHWFSYYTTHWTSLRYSI---NVGQL-----NGPNCTRLLTNM 1740
Query: 12988 LQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNR 13167
+P A+ P G + ++ G H+ IE A MDGT R+I+V+ + PT + +D G R
Sbjct: 1741 AGEPYAIAVNPKRGMMYWTVIGDHSHIEEAAMDGTLRRILVQKHLQRPTGLTVDH-FGER 1799
Query: 13168 IYWVDPKYRRVDAVNIDGSERTTVVHDRH---IPYAVDVFENHIYWLSRESKTLYVQDKF 13338
IYW D + + +V DGS V + P+ +DVFE++IY ++ VQ KF
Sbjct: 1800 IYWADFELSIIGSVMYDGSSPVVSVSSKQGLLHPHRIDVFEDYIYGAGPKNGIFRVQ-KF 1858
Query: 13339 GRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTGFACLCPDGI 13518
G G V VL D++ ++ VS +Y + + C C LC+ PS G C+CP+G
Sbjct: 1859 GHGSVEVLTLDVDKTKSIVVSHRYKQ--LNLPNPCLGLSCDFLCLLNPS-GATCVCPEGK 1915
Query: 13519 VPQLDGSCATQHVEALTMPKQCK--CTNGGKCRL----DGSCECTSDFEGDQCE 13662
+ +G+C H +L + CK C NGG+C L D C C + G +CE
Sbjct: 1916 HIR-NGTC---HENSL-LDDSCKLTCENGGRCILNEKGDLRCHCWPSYSGGRCE 1964
Score = 348 bits (892), Expect = 3e-93
Identities = 299/1101 (27%), Positives = 445/1101 (40%), Gaps = 52/1101 (4%)
Frame = +1
Query: 10141 YETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRI------QQ 10302
Y++ +V EG+A LY + SI +D + R+ +
Sbjct: 15 YQSRTMPDVGSVEGLAYHRAWDTLYWTSSSTSSITRHTVDQTQPGAIDREAVITMSEDDH 74
Query: 10303 PKAIVVHPGKGYLFFTEWSLQ-PYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFS 10479
P + + + +F+T W+ Q P I R L G + D+ PN + ID+ +
Sbjct: 75 PHVLALDECQNLMFWTNWNEQHPSIMRATLTGKNA-----HVVVSTDILTPNGLTIDHRA 129
Query: 10480 DRLFWGDAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKW 10659
++L++ D L +I ++DG+ R I S+ V+D+Y++W+DW R +LR +K+
Sbjct: 130 EKLYFSDGSLGKIERCEYDGSQRHVIVKSGPGTFLSLAVYDNYIFWSDWGRRAILRSNKY 189
Query: 10660 TGKNETILKKTV-QLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPD 10836
TG +L+ + P + V +PC NGGC LCL+ G CSC
Sbjct: 190 TGGETKVLRSDIPHQPMGIIAVANDTNSCELSPCALLNGGCHDLCLLTPDGR-VNCSCRG 248
Query: 10837 QFVLLSDQKTCEPNCT---ERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQR 11007
LL+ + N + +F CG D C+ + CDG P C+D SDE C R
Sbjct: 249 DRTLLASNRCVTKNSSCNIYSEFECGNGD--CVDYVLTCDGIPHCKDKSDEK-LLYCENR 305
Query: 11008 ICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXXEQNCD-KACDPWMFKCAATGRCIPRRFT 11184
C G C N C ++ E +C C F+C G CIPR
Sbjct: 306 SCRSGFKPCYNRRCVPHGKLCDGTNDCGDGSDELDCKVSTCSTVEFRC-TDGTCIPRSAR 364
Query: 11185 XXXXXXXXXRSDEADTLCMSAERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXETPEC 11364
SDE CNN C
Sbjct: 365 CNQNMDCSDASDEKG----------------CNNTDC--------------------THF 388
Query: 11365 AQIECKK-GWTRCSSSYRCI-PNWAFCNGQDDCRDNSDEDKQRCPT-----CDDVGEFRC 11523
++ K G+ RC+S+ C+ P+W C+G +DC D SDE K CP C++ F C
Sbjct: 389 YKLGVKSTGFIRCNSTSLCVLPSW-ICDGSNDCGDYSDELK--CPVQNKHKCEE-NYFGC 444
Query: 11524 ATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTI 11703
SG+CI W+CD + DC D DEL CS ++F C+ KCI +CDG
Sbjct: 445 -PSGRCILNTWVCDGQKDCEDGLDELHCDSS-----CSWNQFACSVHKCISKHWICDGED 498
Query: 11704 QCSDGLDESQ--CTLRRCLPGHRQCDDG-TCIAEHKWCDRKKDCPNAADELHCEDVS-RR 11871
C DGLDES C C C C+ +H CD ++DCP+ +DEL +
Sbjct: 499 DCGDGLDESDNICGAVTCAADMFSCQSSHACVPQHWLCDGERDCPDGSDELSSAGCAPNN 558
Query: 11872 TCSPFEFECANSVCIPRKFMXXXXXXXXXXSDE-----TSSECRS--------------- 11991
TC F C N VCIP++F+ SDE TS CR
Sbjct: 559 TCDENAFMCHNKVCIPKQFVCDHDDDCGDGSDEFLECGTSCSCRDRLQTGCYGSLTSTVQ 618
Query: 11992 -------AQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSFSEYGDCS 12150
QC P FRCA R +N L C+G DC D SDE S C+
Sbjct: 619 YDKFFRYRQCGPE-EFRCADGRCLVNTLWQCDGDFDC--PDSSDEAPINPRCTSAEHSCN 675
Query: 12151 SDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKHICTDVRD 12330
S F C NG+C+ CD +DDCGD S+E C H + + GC C D+
Sbjct: 676 SSFFMCKNGRCIPRDGLCDNRDDCGDGSEEPKC--HINECLSKKI---SGCSQDCQDLPI 730
Query: 12331 GFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGSYLCRCHEDYENNVVVGSM 12510
+ C C GF+ K C+DIDEC+ C+Q C+NT G+Y CRC E YE
Sbjct: 731 SYKCKCWPGFQLKDDG-KTCVDIDECSTGFPCSQQCINTYGTYKCRCTEGYETQ----PD 785
Query: 12511 TGKDCRAKGDAANVMIGADDSLVQLSLH-GSGTNRHXXXXXXXXXXXXXXXXXXPRKELM 12687
CR +V A + L+ +RH R+E +
Sbjct: 786 NQNGCRKPSKVIDVFQEAVELKANPCLNIREAASRHGLNNVIAIDFDY-------REEFI 838
Query: 12688 YWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAVSENIE 12867
YWID S NG++ + M + + I V + G
Sbjct: 839 YWIDSSR--------PNGSRINR----------MCLNGSDIKVWWRRG------------ 868
Query: 12868 NGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSD 13047
+ L R + + + G + + DG ++ + +P AL R+ ++D
Sbjct: 869 DELGVGRNLYWIDCCEYPHIGRVGM---DGTNQSVVIETKISRPMALTIDYVNHRLYWAD 925
Query: 13048 AGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVN-IDGS 13224
IE ++MDG+HR + + ++ + E + IYW D K + + V+ G+
Sbjct: 926 EN---HIEFSNMDGSHRHKVPNQDIPGVIALTLFE---DYIYWTDGKTKSLSRVHKTSGA 979
Query: 13225 ERTTVVHDRHIPYAVDVFENH 13287
+R ++++ H + V+ ++
Sbjct: 980 DRLSLIYSWHAITDIQVYHSY 1000
Score = 334 bits (856), Expect = 4e-89
Identities = 292/1107 (26%), Positives = 421/1107 (37%), Gaps = 189/1107 (17%)
Frame = +1
Query: 2581 LFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDF 2760
L++ + I R +DG N V+ T + RP + ID+ +RL W D S MD
Sbjct: 877 LYWIDCCEYPHIGRVGMDGTNQSVVIETKISRPMALTIDYVNHRLYWADENHIEFSNMDG 936
Query: 2761 DGKNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIF 2940
++ V + D P +A+T+ +YIY+ + S+ RVHK +G AD S+
Sbjct: 937 SHRHKVP-NQDIPGVIALTLFEDYIYWTDGKTKSLSRVHKTSG----------ADRLSLI 985
Query: 2941 SLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINKENNH 3120
+ I D H R P ++H CAC F + +N
Sbjct: 986 ------YSWHAITDIQVYHSYRQPD-------GPGKTHT------CACPTNFYLAADN-- 1024
Query: 3121 SCQKDPAEKIEQLCSSNST--QFQCKNGRCIPKEWKCDGENDCLDESDEIDEKGDK---- 3282
+ C SN T QF+CK +CIP WKCD +DC D SDE D+ +
Sbjct: 1025 -----------RTCLSNCTASQFRCKTDKCIPFWWKCDTVDDCGDGSDEPDDCPEFKCQP 1073
Query: 3283 ----------------CFHETECAENT-------IKCRNTKKCIPAQXXXXXXXXXXXXX 3393
C E +C +N+ KC KKCIP
Sbjct: 1074 GRFQCGTGLCALPAFICDGENDCGDNSDELNCGQFKCTKNKKCIPVNLRCNGQDDCGDEE 1133
Query: 3394 XX----------------XVKYC-------------------KDGQKPVCAAKKFQCDNH 3468
K+C + K C +FQC N+
Sbjct: 1134 DERDCPENSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEANCDKKTCGPHEFQCKNN 1193
Query: 3469 RCIPEQWKXXXXXXXXXXXXEKLEMCGNATCAANQFSCANGRCIPIYWLCDGDNDCYDGT 3648
CIP+ W+ E E C TC F C+NG C+ + CDG+ DC DG+
Sbjct: 1194 NCIPDHWRCDSQNDCSDNSDE--ENCKPQTCTLRDFLCSNGDCVSSRFWCDGEFDCADGS 1251
Query: 3649 DE------DKERCPPVQCSALQFRCANGRQCVPLR----NHXXXXXXXXXXXXXXXXAVT 3798
DE K+ C CS QF+C+NG QC+ + H V
Sbjct: 1252 DEVGISVNAKKNCE-TSCSKDQFQCSNG-QCLSAKWKCDGHEDCKYGEDEKNCEPAFPVC 1309
Query: 3799 AES----------------------------------CTPDQFKCVSSGLCIPASWKXXX 3876
+ S C DQF+C + CIP W
Sbjct: 1310 SSSEYMCASGGCLSASLKCNGETDCVDGSDEMDCVTECKEDQFQCRNKAYCIPIRWLCDG 1369
Query: 3877 XXXXXXXSDEPKFGCTSGRQCSSDQFKCGNGRCILNNWLCDGENDCGDGSDE-------- 4032
SDE G G C +D+F C N C L+ W+CDGE+DCGD SDE
Sbjct: 1370 IYDCVDGSDEENCG-RGGSICRADEFLCNNSLCKLHFWVCDGEDDCGDNSDEVPDMCVKF 1428
Query: 4033 --------------------------------SSERGCK--TSMNARKCPFEHVACENDQ 4110
S E C S + C + C N
Sbjct: 1429 LCPPTRPYRCRNDRICLQLEKMCNGINDCGDNSDEEHCSGTLSFKSEPCKKDEFTCNN-- 1486
Query: 4111 ETCIPLHQLCDGKTHCPGGTDEGGRC---ARDLC--SADRAGCSFKCHNSPNGPICSCPF 4275
CIP+ CDG C G+DE G + C + + G C+ C C
Sbjct: 1487 RNCIPMELQCDGLDDCGDGSDEQGCMQTPTQHTCENNGNPCGDDAYCNQIRTSVFCRCKP 1546
Query: 4276 GEQL-VNKTKCEPENECLDSSSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDT 4452
G Q + +C NECL CSQ C + + + C CD+ ++ +K +A +D
Sbjct: 1547 GFQRNIKGRECADLNECLVFGICSQHCLNTRGSYKCVCDQNFQ---EKNNSCIAKGSEDQ 1603
Query: 4453 RIYVSNRNRIY---YSDHKLDNWHTFGAIVENAIALAWDSLTDR--IYWS---------- 4587
+Y++N I Y + + + N+ D R I WS
Sbjct: 1604 ALYIANDTDILGFVYPFNYSGSHQQISHVEHNSRITGMDVYYQRNVIVWSTQFNPGGIFY 1663
Query: 4588 ---DIREKKILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVDSSLN--------- 4731
D REK+ ++ I IA+DWV N+YW D S
Sbjct: 1664 TMIDAREKRQANSG--------LICPEFKRPRDIAVDWVTGNVYWTDHSRMHWFSYYTTH 1715
Query: 4732 ------TIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQNPCIERASMDG 4893
+I V L P LL + +P IAV+P++G+M+WT G + IE A+MDG
Sbjct: 1716 WTSLRYSINVGQLNGPNCTRLLTNM-AGEPYAIAVNPKRGMMYWTVIGDHSHIEEAAMDG 1774
Query: 4894 TDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPH 5073
T R+I+V+ + P + +D+ +R+Y+AD +L I V YDGS ++S + + HPH
Sbjct: 1775 TLRRILVQKHLQRPTGLTVDHFGERIYWADFELSIIGSVMYDGSSPVVSVSSKQGLLHPH 1834
Query: 5074 ALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPC 5253
+ +FED +Y + + +V K+ +G+ E + K +V H Q + NPC
Sbjct: 1835 RIDVFEDYIYGAGPKNGIFRV-QKFGHGSV-EVLTLDVDKTKSIVVSHRYKQLNLP-NPC 1891
Query: 5254 STNPCSHLCLLNNKNTFTCKCPMGEKL 5334
C LCLLN TC CP G+ +
Sbjct: 1892 LGLSCDFLCLLNPSGA-TCVCPEGKHI 1917
Score = 288 bits (736), Expect = 4e-75
Identities = 209/750 (27%), Positives = 314/750 (41%), Gaps = 88/750 (11%)
Frame = +1
Query: 139 NTASSVCNENDFRCNDGKCIRTEWX-------XXXXXXXXXXXXXXXXPHPGCKSDQWQC 297
N C DF C++G C+ + + C DQ+QC
Sbjct: 1216 NCKPQTCTLRDFLCSNGDCVSSRFWCDGEFDCADGSDEVGISVNAKKNCETSCSKDQFQC 1275
Query: 298 DTYTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKC 477
+ C++ +CD DC G DEK+C + CSS +MCA G C S KC
Sbjct: 1276 S-----NGQCLSAKWKCDGHEDCKYGEDEKNCEPAFPVCSSSE-YMCASGG-CLSASLKC 1328
Query: 478 DGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCE 657
+G+ DC D SDE D T C + QF+C +K CI W+CDG DC DGSDE +
Sbjct: 1329 NGETDCVDGSDEMDCV----TECKEDQFQCRNKAYCIPIRWLCDGIYDCVDGSDEENCGR 1384
Query: 658 FKK-CTANEFQCKNKRCQPRKFRCDYYDDCGDNSDE--DECGEYRCPPGK-WNCPGTGHC 825
C A+EF C N C+ + CD DDCGDNSDE D C ++ CPP + + C C
Sbjct: 1385 GGSICRADEFLCNNSLCKLHFWVCDGEDDCGDNSDEVPDMCVKFLCPPTRPYRCRNDRIC 1444
Query: 826 IDQLKLCDGSKDCADGADEQQCSQNL-------------CPSLGC--------------- 921
+ K+C+G DC D +DE+ CS L C + C
Sbjct: 1445 LQLEKMCNGINDCGDNSDEEHCSGTLSFKSEPCKKDEFTCNNRNCIPMELQCDGLDDCGD 1504
Query: 922 ---QAGCHPSP--HGGE--------------------CTCPSGYKLDDRFHRTCSDINEC 1026
+ GC +P H E C C G++ + + R C+D+NEC
Sbjct: 1505 GSDEQGCMQTPTQHTCENNGNPCGDDAYCNQIRTSVFCRCKPGFQRNIK-GRECADLNEC 1563
Query: 1027 AEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARR 1206
FG C Q C N R + C C ++ K+N C++ ++ L++A
Sbjct: 1564 LVFGICSQHCLNTRGSYKCVC--------DQNFQEKNNS-----CIAKGSEDQALYIAND 1610
Query: 1207 EGL----YRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGE 1374
+ Y N +++ + I G+D Y I W+ + + D E
Sbjct: 1611 TDILGFVYPFNYSGSHQQISHVEHNSRITGMDVYYQRNVIVWSTQFNPGGIFYTMIDARE 1670
Query: 1375 ISQIKK-LSLKSLVYPRCLAVDWITNTLYIIESGSRR---------------IDVSSYDG 1506
Q L PR +AVDW+T +Y + I+V +G
Sbjct: 1671 KRQANSGLICPEFKRPRDIAVDWVTGNVYWTDHSRMHWFSYYTTHWTSLRYSINVGQLNG 1730
Query: 1507 ERRTVLLADGLTLPLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVSG 1677
T LL + P IA++P RG M++T + +E AAMDGT RR LV H + +G
Sbjct: 1731 PNCTRLLTNMAGEPYAIAVNPKRGMMYWTVIGDHSHIEEAAMDGTLRRILVQKHLQRPTG 1790
Query: 1678 IVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTR 1857
+ VD +R+YW D ++ + S+ Y G+ + + HP + +F+ Y+Y +
Sbjct: 1791 LTVDHFGERIYWADFELSIIGSVMYDGSSPVVSVSSKQGLLHPHRIDVFEDYIYGAG-PK 1849
Query: 1858 LGVIQVEKFG-SDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADC 2034
G+ +V+KFG ++L + + I H Q + + NPC C
Sbjct: 1850 NGIFRVQKFGHGSVEVLTLDVDKT---KSIVVSHRYKQ----------LNLPNPCLGLSC 1896
Query: 2035 EGMCILSKDNGGFGVGYKCACPIGQKLVNG 2124
+ +C+L+ G C CP G+ + NG
Sbjct: 1897 DFLCLLNPS------GATCVCPEGKHIRNG 1920
Score = 257 bits (656), Expect = 7e-66
Identities = 263/1089 (24%), Positives = 414/1089 (37%), Gaps = 111/1089 (10%)
Frame = +1
Query: 2431 LYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRD--PVSVVVHPWKGLLFYAE-AM 2601
LY+ + +S+ + +T P + R +IT D P + + + L+F+
Sbjct: 38 LYWTSSSTSSITRHTVDQT---QPGAIDREAVITMSEDDHPHVLALDECQNLMFWTNWNE 94
Query: 2602 RPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVK 2781
+ +I R + G+N V+ +T + P+ + ID +L + D L I ++DG
Sbjct: 95 QHPSIMRATLTGKNAHVVVSTDILTPNGLTIDHRAEKLYFSDGSLGKIERCEYDGSQRHV 154
Query: 2782 LDIDNPIP-VAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVRE----------FGADE 2928
+ P +++ + + YI++ +I R +K GG +K++R A++
Sbjct: 155 IVKSGPGTFLSLAVYDNYIFWSDWGRRAILRSNKYTGGETKVLRSDIPHQPMGIIAVAND 214
Query: 2929 RSIFSLKACSHQNQPI-------PDDSREHPCRASQCTQLCFATPSESHPNELEAKCACR 3087
+ L C+ N PD CR + +++ + ++ C
Sbjct: 215 TNSCELSPCALLNGGCHDLCLLTPDGRVNCSCRGDRTLLASNRCVTKNSSCNIYSEFECG 274
Query: 3088 QG----FMINKENNHSCQKDPAEKIEQLCSSNSTQF---QCKNGRCIPKEWKCDGENDCL 3246
G +++ + C+ EK+ C + S + C N RC+P CDG NDC
Sbjct: 275 NGDCVDYVLTCDGIPHCKDKSDEKL-LYCENRSCRSGFKPCYNRRCVPHGKLCDGTNDCG 333
Query: 3247 DESDEIDEK-------------------GDKCFHETECAE--------NT---------- 3315
D SDE+D K +C +C++ NT
Sbjct: 334 DGSDELDCKVSTCSTVEFRCTDGTCIPRSARCNQNMDCSDASDEKGCNNTDCTHFYKLGV 393
Query: 3316 -----IKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNHRCIP 3480
I+C +T C+ C K C F C + RCI
Sbjct: 394 KSTGFIRCNSTSLCVLPSWICDGSNDCGDYSDELK--CPVQNKHKCEENYFGCPSGRCIL 451
Query: 3481 EQWKXXXXXXXXXXXXEKLEMCGNATCAANQFSCANGRCIPIYWLCDGDNDCYDGTDEDK 3660
W E + +++C+ NQF+C+ +CI +W+CDG++DC DG DE
Sbjct: 452 NTWVCDGQKDCEDGLDE---LHCDSSCSWNQFACSVHKCISKHWICDGEDDCGDGLDESD 508
Query: 3661 ERCPPVQCSALQFRCANGRQCVPLRNHXXXXXXXXXXXXXXXXAVTAES----------- 3807
C V C+A F C + CVP A A +
Sbjct: 509 NICGAVTCAADMFSCQSSHACVPQHWLCDGERDCPDGSDELSSAGCAPNNTCDENAFMCH 568
Query: 3808 ---CTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSG-------------RQC 3939
C P QF C C S + D + GC RQC
Sbjct: 569 NKVCIPKQFVCDHDDDCGDGSDEFLECGTSCSCRDRLQTGCYGSLTSTVQYDKFFRYRQC 628
Query: 3940 SSDQFKCGNGRCILNN-WLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQET 4116
++F+C +GRC++N W CDG+ DC D SDE+ TS C C+N +
Sbjct: 629 GPEEFRCADGRCLVNTLWQCDGDFDCPDSSDEAPINPRCTSAE-HSCNSSFFMCKNGR-- 685
Query: 4117 CIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCSFKCHNSPNGPICSCPFGEQLVNK 4296
CIP LCD + C G++E + S +GCS C + P C C G QL +
Sbjct: 686 CIPRDGLCDNRDDCGDGSEEPKCHINECLSKKISGCSQDCQDLPISYKCKCWPGFQLKDD 745
Query: 4297 TK-CEPENECLDSSSCSQRCKDEKHGFTCSCDEGYELDVD-----KRTCKVADNVKDTRI 4458
K C +EC CSQ+C + + C C EGYE D ++ KV D ++
Sbjct: 746 GKTCVDIDECSTGFPCSQQCINTYGTYKCRCTEGYETQPDNQNGCRKPSKVIDVFQEAVE 805
Query: 4459 YVSN---RNRIYYSDHKLDNWHTFGAIVENAIALAWDSLTDRIYWSDIREKKILSANRNG 4629
+N R S H L+N IA+ +D + IYW D S+ NG
Sbjct: 806 LKANPCLNIREAASRHGLNN----------VIAIDFDYREEFIYWID-------SSRPNG 848
Query: 4630 TNATVFIADGLDIT----EGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVS 4797
+ +G DI G L VGRNLY
Sbjct: 849 SRINRMCLNGSDIKVWWRRGDELG-VGRNLY----------------------------- 878
Query: 4798 QPRGIAVDPRKGVMFWTDWGQNPCIERASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYF 4977
W D + P I R MDGT++ ++++TKI P + +DY R+Y+
Sbjct: 879 ---------------WIDCCEYPHIGRVGMDGTNQSVVIETKISRPMALTIDYVNHRLYW 923
Query: 4978 ADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNG 5157
AD + I+F N DGS R +V ++ + AL +FED +Y++D + + L K +G
Sbjct: 924 ADE--NHIEFSNMDGSHRHKV--PNQDIPGVIALTLFEDYIYWTDGKTKSLSRVHK-TSG 978
Query: 5158 TTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTNPCSHLCLLNNKNTFTCKCPMGEKLD 5337
+++ + H QP + P T+ TC CP L
Sbjct: 979 ADRLSLIYSWHAITDIQVYHSYRQP---DGPGKTH--------------TCACPTNFYLA 1021
Query: 5338 ASGKKCIDD 5364
A + C+ +
Sbjct: 1022 ADNRTCLSN 1030
Score = 189 bits (480), Expect = 2e-45
Identities = 156/578 (26%), Positives = 233/578 (39%), Gaps = 48/578 (8%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAE 336
C EN F C G+CI W C +Q+ C + CI++
Sbjct: 437 CEENYFGCPSGRCILNTWVCDGQKDCEDGLDELHCDS-SCSWNQFACSVH-----KCISK 490
Query: 337 YQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEK 516
+ CD DC DG DE D V C++ ++F C C CDG+ DC D SDE
Sbjct: 491 HWICDGEDDCGDGLDESDNICGAVTCAA-DMFSCQSSHACVPQHWLCDGERDCPDGSDEL 549
Query: 517 DS--CSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTC------------ 654
S C+ N+T C + F C +K CI K +VCD DC DGSDE C
Sbjct: 550 SSAGCAPNNT-CDENAFMCHNKV-CIPKQFVCDHDDDCGDGSDEFLECGTSCSCRDRLQT 607
Query: 655 ----------------EFKKCTANEFQCKNKRCQPRK-FRCDYYDDCGDNSDEDECGEYR 783
+++C EF+C + RC ++CD DC D+SDE R
Sbjct: 608 GCYGSLTSTVQYDKFFRYRQCGPEEFRCADGRCLVNTLWQCDGDFDCPDSSDEAPINP-R 666
Query: 784 CPPGKWNCPGT------GHCIDQLKLCDGSKDCADGADEQQCSQNLCPSL---GCQAGCH 936
C + +C + G CI + LCD DC DG++E +C N C S GC C
Sbjct: 667 CTSAEHSCNSSFFMCKNGRCIPRDGLCDNRDDCGDGSEEPKCHINECLSKKISGCSQDCQ 726
Query: 937 PSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQM 1116
P +C C G++L D +TC DI+EC+ C Q C N + C C T
Sbjct: 727 DLPISYKCKCWPGFQLKDD-GKTCVDIDECSTGFPCSQQCINTYGTYKCRC-----TEGY 780
Query: 1117 EHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFD 1296
E P N + V + V + + NP E + IDFD
Sbjct: 781 ETQPDNQNGCRKPSKV--------IDVFQEAVELKANPCLNIREAASRHGLNNVIAIDFD 832
Query: 1297 YGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDW-------ITNTL 1455
Y + I+W D + S+I ++ L + V W + L
Sbjct: 833 YREEFIYWIDSSRPNG-----------SRINRMCLNG----SDIKVWWRRGDELGVGRNL 877
Query: 1456 YIIESGS-RRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTNQLKLEAAAMDGT 1632
Y I+ I DG ++V++ ++ P+ + +D + +++ ++ +E + MDG+
Sbjct: 878 YWIDCCEYPHIGRVGMDGTNQSVVIETKISRPMALTIDYVNHRLYWADENHIEFSNMDGS 937
Query: 1633 NRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESI 1746
+R + N V I + + +YW D K L +
Sbjct: 938 HRHKVPNQDIPGV--IALTLFEDYIYWTDGKTKSLSRV 973
Score = 170 bits (430), Expect = 1e-39
Identities = 104/312 (33%), Positives = 139/312 (44%), Gaps = 1/312 (0%)
Frame = +1
Query: 124 ISASVNTASSVCNENDFRCNDGKCIRTEWX-XXXXXXXXXXXXXXXXPHPGCKSDQWQCD 300
++A T S C + FRC KCI W P C+ ++QC
Sbjct: 1020 LAADNRTCLSNCTASQFRCKTDKCIPFWWKCDTVDDCGDGSDEPDDCPEFKCQPGRFQCG 1079
Query: 301 TYTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCD 480
T C CD DC D SDE +C F C ++C V+ +C+
Sbjct: 1080 TGL-----CALPAFICDGENDCGDNSDELNC----------GQFKCTKNKKCIPVNLRCN 1124
Query: 481 GKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEF 660
G+ DC D DE+D C N +C F+C CI K WVCD DCAD SDE + C+
Sbjct: 1125 GQDDCGDEEDERD-CPEN--SCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEAN-CDK 1180
Query: 661 KKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLK 840
K C +EFQCKN C P +RCD +DC DNSDE+ C C + C G C+
Sbjct: 1181 KTCGPHEFQCKNNNCIPDHWRCDSQNDCSDNSDEENCKPQTCTLRDFLC-SNGDCVSSRF 1239
Query: 841 LCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDIN 1020
CDG DCADG+DE S N + C S + C +G L ++ C
Sbjct: 1240 WCDGEFDCADGSDEVGISVN------AKKNCETSCSKDQFQCSNGQCLSAKW--KCDGHE 1291
Query: 1021 ECAEFGYCDQLC 1056
+C ++G ++ C
Sbjct: 1292 DC-KYGEDEKNC 1302
Score = 146 bits (368), Expect = 2e-32
Identities = 116/365 (31%), Positives = 154/365 (41%), Gaps = 35/365 (9%)
Frame = +1
Query: 112 RSRIISASVNTASSVCN-ENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQ 288
R+ + S T +S CN ++F C +G C+ PH KSD+
Sbjct: 250 RTLLASNRCVTKNSSCNIYSEFECGNGDCV------------DYVLTCDGIPHCKDKSDE 297
Query: 289 --WQCDTYTWHSV-------SCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCA 441
C+ + S C+ + CD DC DGSDE DC ST CS+ F C
Sbjct: 298 KLLYCENRSCRSGFKPCYNRRCVPHGKLCDGTNDCGDGSDELDCKVST--CSTVE-FRCT 354
Query: 442 DGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQ---------FRCADKTQCIQK 594
DG C S +C+ DC D SDEK N+T C + RC + C+
Sbjct: 355 DGT-CIPRSARCNQNMDCSDASDEKGC---NNTDCTHFYKLGVKSTGFIRCNSTSLCVLP 410
Query: 595 SWVCDGSKDCADGSDEPDTCEFK---KCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDED 765
SW+CDGS DC D SDE C + KC N F C + RC + CD DC D DE
Sbjct: 411 SWICDGSNDCGDYSDEL-KCPVQNKHKCEENYFGCPSGRCILNTWVCDGQKDCEDGLDEL 469
Query: 766 ECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLGCQA------ 927
C + C ++ C CI + +CDG DC DG DE S N+C ++ C A
Sbjct: 470 HC-DSSCSWNQFAC-SVHKCISKHWICDGEDDCGDGLDE---SDNICGAVTCAADMFSCQ 524
Query: 928 ---GCHPSPH--GGECTCPSGYKLDDRFHRTCSDINECAEFGYC--DQLCANHRPGFTCS 1086
C P GE CP G D+ C+ N C E + +++C + F C
Sbjct: 525 SSHACVPQHWLCDGERDCPDG--SDELSSAGCAPNNTCDENAFMCHNKVCIPKQ--FVCD 580
Query: 1087 CLGDC 1101
DC
Sbjct: 581 HDDDC 585
Score = 125 bits (313), Expect = 4e-26
Identities = 82/277 (29%), Positives = 105/277 (37%), Gaps = 34/277 (12%)
Frame = +1
Query: 304 YTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQ-NVFMCADGRQCFDVSKKCD 480
Y+WH+++ I Y + D P T C+ N ++ AD R C
Sbjct: 986 YSWHAITDIQVYH----------SYRQPDGPGKTHTCACPTNFYLAADNRTCL------- 1028
Query: 481 GKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEF 660
+ C QFRC +CI W CD DC DGSDEPD C
Sbjct: 1029 -------------------SNCTASQFRCKTD-KCIPFWWKCDTVDDCGDGSDEPDDCPE 1068
Query: 661 KKCTANEFQC---------------------------------KNKRCQPRKFRCDYYDD 741
KC FQC KNK+C P RC+ DD
Sbjct: 1069 FKCQPGRFQCGTGLCALPAFICDGENDCGDNSDELNCGQFKCTKNKKCIPVNLRCNGQDD 1128
Query: 742 CGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLGC 921
CGD DE +C E C P + C T HCI +L +CD DCAD +DE C + C
Sbjct: 1129 CGDEEDERDCPENSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEANCDKKTC----- 1183
Query: 922 QAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAE 1032
PH E C + + D H C N+C++
Sbjct: 1184 ------GPH--EFQCKNNNCIPD--HWRCDSQNDCSD 1210
Score = 101 bits (251), Expect = 6e-19
Identities = 65/244 (26%), Positives = 117/244 (47%), Gaps = 15/244 (6%)
Frame = +1
Query: 4672 EGIALDWVGRNLYWVDSSLNTIEVANLEDPK-----QRTLLVHQNVSQPRGIAVDPRKGV 4836
EG+A LYW SS ++I ++ + + ++ P +A+D + +
Sbjct: 27 EGLAYHRAWDTLYWTSSSTSSITRHTVDQTQPGAIDREAVITMSEDDHPHVLALDECQNL 86
Query: 4837 MFWTDWG-QNPCIERASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVN 5013
MFWT+W Q+P I RA++ G + ++V T I PN + +D+ +++YF+D L I+
Sbjct: 87 MFWTNWNEQHPSIMRATLTGKNAHVVVSTDILTPNGLTIDHRAEKLYFSDGSLGKIERCE 146
Query: 5014 YDGSGRTQVLAS--SKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTF 5187
YDGS R ++ S F+ +LA++++ +++SD + + KY G T S
Sbjct: 147 YDGSQRHVIVKSGPGTFL----SLAVYDNYIFWSDWGRRAILRSNKYTGGETKVLRSDIP 202
Query: 5188 SKALGVVAVHPVLQPVIKNNPCSTNPCS-------HLCLLNNKNTFTCKCPMGEKLDASG 5346
+ +G++AV N C +PC+ LCLL C C G++ +
Sbjct: 203 HQPMGIIAV------ANDTNSCELSPCALLNGGCHDLCLLTPDGRVNCSC-RGDRTLLAS 255
Query: 5347 KKCI 5358
+C+
Sbjct: 256 NRCV 259
Score = 87.4 bits (215), Expect = 9e-15
Identities = 49/149 (32%), Positives = 72/149 (47%), Gaps = 6/149 (4%)
Frame = +1
Query: 478 DGKYDCRDLSDE----KDSCSRNHTACFQY-QFRCADKTQCIQKSWVCDGSKDCADGSDE 642
DG+ +C D + C +++C Y +F C + C+ CDG C D SDE
Sbjct: 239 DGRVNCSCRGDRTLLASNRCVTKNSSCNIYSEFECGNG-DCVDYVLTCDGIPHCKDKSDE 297
Query: 643 PDT-CEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTG 819
CE + C + C N+RC P CD +DCGD SDE +C C ++ C G
Sbjct: 298 KLLYCENRSCRSGFKPCYNRRCVPHGKLCDGTNDCGDGSDELDCKVSTCSTVEFRCT-DG 356
Query: 820 HCIDQLKLCDGSKDCADGADEQQCSQNLC 906
CI + C+ + DC+D +DE+ C+ C
Sbjct: 357 TCIPRSARCNQNMDCSDASDEKGCNNTDC 385
Score = 84.0 bits (206), Expect = 1e-13
Identities = 69/261 (26%), Positives = 120/261 (45%), Gaps = 14/261 (5%)
Frame = +1
Query: 1396 SLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDG------ERRTVLLADGLTLPLDI 1557
S++ L Y R W +TLY S + I + D +R V+ P +
Sbjct: 25 SVEGLAYHRA----W--DTLYWTSSSTSSITRHTVDQTQPGAIDREAVITMSEDDHPHVL 78
Query: 1558 ALDPLRGEMFFTN----QLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPK 1725
ALD + MF+TN + A + G N +V+T +G+ +D A+++Y+ D
Sbjct: 79 ALDECQNLMFWTNWNEQHPSIMRATLTGKNAHVVVSTDILTPNGLTIDHRAEKLYFSDGS 138
Query: 1726 VDRLESIDYQGNDRRIVAQGMNVVPHPF-GLALFDQYLYWTDWTRLGVIQVEKF-GSDTK 1899
+ ++E +Y G+ R ++ + P F LA++D Y++W+DW R +++ K+ G +TK
Sbjct: 139 LGKIERCEYDGSQRHVIVKSG---PGTFLSLAVYDNYIFWSDWGRRAILRSNKYTGGETK 195
Query: 1900 LLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCT--NADCEGMCILSKDNGGF 2073
+L S+ + PMGI A + C +PC N C +C+L+ D
Sbjct: 196 VLRSDIPHQ--PMGIIAV------ANDTNSCEL----SPCALLNGGCHDLCLLTPDG--- 240
Query: 2074 GVGYKCACPIGQKLVNGKRCI 2136
C+C + L+ RC+
Sbjct: 241 --RVNCSCRGDRTLLASNRCV 259
Score = 82.4 bits (202), Expect = 3e-13
Identities = 63/256 (24%), Positives = 109/256 (41%), Gaps = 18/256 (7%)
Frame = +1
Query: 6265 GNCDHICIPLMFAQRTCTCANGYVKDGQTSCKLFDESFVIVATKTKVIG--YPIDETQSK 6438
G C C+ + + N K+ K ++ + +A T ++G YP + + S
Sbjct: 1567 GICSQHCLNTRGSYKCVCDQNFQEKNNSCIAKGSEDQALYIANDTDILGFVYPFNYSGSH 1626
Query: 6439 GVAMEPIGGLSITGVDYDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIK 6618
ITG+D Y+ I ++ N G YT+ ++ + + K
Sbjct: 1627 QQISHVEHNSRITGMDVYYQRNVI--VWSTQFNPGGIFYTMIDAREKRQANSGLICPEFK 1684
Query: 6619 ---SLAIDWINYNMYFINHD-------------AERTNIEVSKLDGTYRKILLTTKTETP 6750
+A+DW+ N+Y+ +H + R +I V +L+G LLT P
Sbjct: 1685 RPRDIAVDWVTGNVYWTDHSRMHWFSYYTTHWTSLRYSINVGQLNGPNCTRLLTNMAGEP 1744
Query: 6751 SSIAVDPVSRYLYWADQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSD 6930
+IAV+P +YW G I+ + +DG+ R ++V + PT L VD + IYW+D
Sbjct: 1745 YAIAVNPKRGMMYWTVIGDHSHIEEAAMDGTLRRILVQKHLQRPTGLTVDHFGERIYWAD 1804
Query: 6931 AKMDGIYRVRSTGGTP 6978
++ I V G +P
Sbjct: 1805 FELSIIGSVMYDGSSP 1820
Score = 73.6 bits (179), Expect = 1e-10
Identities = 55/182 (30%), Positives = 95/182 (51%), Gaps = 5/182 (2%)
Frame = +1
Query: 6469 SITGVDYDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIKS----LAIDW 6636
S+ G+ Y T+Y +S IT +T+ ++ P A+ R+++ +++ LA+D
Sbjct: 25 SVEGLAYHRAWDTLYWTSSS--TSSITRHTVDQTQPGAIDREAVITMSEDDHPHVLALDE 82
Query: 6637 INYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPT 6816
M++ N + + +I + L G ++++T TP+ + +D + LY++D G
Sbjct: 83 CQNLMFWTNWNEQHPSIMRATLTGKNAHVVVSTDILTPNGLTIDHRAEKLYFSD-GSLGK 141
Query: 6817 IQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRV-RSTGGTPELVRS 6993
I+R DGS+R VIV SG T L + V I+WSD I R + TGG +++RS
Sbjct: 142 IERCEYDGSQRHVIVKSG--PGTFLSLAVYDNYIFWSDWGRRAILRSNKYTGGETKVLRS 199
Query: 6994 DI 6999
DI
Sbjct: 200 DI 201
Score = 71.6 bits (174), Expect = 5e-10
Identities = 112/505 (22%), Positives = 184/505 (36%), Gaps = 67/505 (13%)
Frame = +1
Query: 7429 NLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAENPRLVFGASKQPHAKEIRHISDMKL 7608
N + +DV +R V + +++M +A R P K R D+ +
Sbjct: 1635 NSRITGMDVYYQRNVIVWSTQFNPGGIFYTMIDAREKRQANSGLICPEFKRPR---DIAV 1691
Query: 7609 DWLTQKIYFT-----------TGRGGKVMAIDTAGE-------HLSTIASGDWTYALAID 7734
DW+T +Y+T T + G+ L T +G+ YA+A++
Sbjct: 1692 DWVTGNVYWTDHSRMHWFSYYTTHWTSLRYSINVGQLNGPNCTRLLTNMAGE-PYAIAVN 1750
Query: 7735 PCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVDFRNQKIYWA 7914
P G+++W+ G + IE + + G R+++V + + P + VD ++IYWA
Sbjct: 1751 PKRGMMYWTVIGDHS-------HIEEAAMDGTLRRILVQKHLQRPTGLTVDHFGERIYWA 1803
Query: 7915 DVNRLNIEVADYDGQNRKVIASGYRA----KSLDIWDRWLYMSDPLSNGVFRIDKESGSG 8082
D I YDG + V S + +D+++ ++Y + P NG+FR+ K
Sbjct: 1804 DFELSIIGSVMYDGSSPVVSVSSKQGLLHPHRIDVFEDYIYGAGP-KNGIFRVQKFGHGS 1862
Query: 8083 LENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLCTVVADDIGLAA 8262
+E + D ++ V + N LC + G +C I
Sbjct: 1863 VEVLTLDVDKTKSIVVSHRYKQLNLPNPCLGLSCDFLCLLNPSGATCVCP-EGKHIRNGT 1921
Query: 8263 SKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSEPAKECLPPY-----------NFQCGDG 8409
+D+ +L E G +C+L + C P Y N+ G
Sbjct: 1922 CHENSLLDDSCKLTCENG----GRCIL-NEKGDLRCHCWPSYSGGRCEVNHCSNYCQNGG 1976
Query: 8410 SCI--------------LLGATCDSKPDCADASDE---------NPNYCNTRSCPEDYNL 8520
+CI G C K C D+ N YC+ C DY
Sbjct: 1977 TCIPSALGRPTCICALGFTGPNC-GKTVCEDSCHNGGSCVVTAGNQPYCH---CQADY-- 2030
Query: 8521 CTNRRCIDSAKKCNHI----DDC---GDGSDELDCPS---AVAC-AEGTFPCSNGHCINQ 8667
T RC C+H + C DGS E CP+ C + C GHCI
Sbjct: 2031 -TGDRC--QYYVCHHYCVNSESCSIGNDGSVECVCPTRYEGPKCEIDKCVRCHGGHCIIN 2087
Query: 8668 TKVCDGHNDCHDEQVSDESLATCPG 8742
D +C + +++ S C G
Sbjct: 2088 QDNEDIFCNCTNGKIA-SSCQLCDG 2111
Score = 68.9 bits (167), Expect = 3e-09
Identities = 61/243 (25%), Positives = 102/243 (41%), Gaps = 5/243 (2%)
Frame = +1
Query: 6271 CDHICIPLMFAQRTCTCANGYVK--DGQTSCKLFDESFVIVATKTKVIGYPIDETQSKGV 6444
C CI + C C GY D Q C+ + + ++ P +
Sbjct: 761 CSQQCINT-YGTYKCRCTEGYETQPDNQNGCRKPSKVIDVFQEAVELKANPCLNIRE--- 816
Query: 6445 AMEPIGGLSITGVDYDYESKTIYVAEASGINKG-ITAYTIGESSPRAVIR--DSIGSLTI 6615
A G ++ +D+DY + IY ++S N I + S + R D +G
Sbjct: 817 AASRHGLNNVIAIDFDYREEFIYWIDSSRPNGSRINRMCLNGSDIKVWWRRGDELG---- 872
Query: 6616 KSLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWA 6795
+ N+Y+I+ E +I +DGT + +++ TK P ++ +D V+ LYWA
Sbjct: 873 -------VGRNLYWIDC-CEYPHIGRVGMDGTNQSVVIETKISRPMALTIDYVNHRLYWA 924
Query: 6796 DQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGT 6975
D+ I+ S +DGS R + + I P + + + IYW+D K + RV T G
Sbjct: 925 DENH---IEFSNMDGSHRHKVPNQDI--PGVIALTLFEDYIYWTDGKTKSLSRVHKTSGA 979
Query: 6976 PEL 6984
L
Sbjct: 980 DRL 982
Score = 63.9 bits (154), Expect = 1e-07
Identities = 43/145 (29%), Positives = 68/145 (46%), Gaps = 8/145 (5%)
Frame = +1
Query: 6772 VSRYLYWADQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSD------A 6933
V R LYW D + P I R +DG+ + V++ + I+ P L +D + +YW+D +
Sbjct: 873 VGRNLYWIDCCEYPHIGRVGMDGTNQSVVIETKISRPMALTIDYVNHRLYWADENHIEFS 932
Query: 6934 KMDGIYRVRSTGGTPELVRSDIASAAGVALHGQNMYWTDNRLEKLFRA--TSKPNQTSLL 7107
MDG +R ++ DI + L +YWTD + + L R TS ++ SL+
Sbjct: 933 NMDGSHR-------HKVPNQDIPGVIALTLFEDYIYWTDGKTKSLSRVHKTSGADRLSLI 985
Query: 7108 LSPTTVAASLKDIGDVAVFSSNNQP 7182
S I D+ V+ S QP
Sbjct: 986 Y-------SWHAITDIQVYHSYRQP 1003
Score = 63.5 bits (153), Expect = 1e-07
Identities = 51/203 (25%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Frame = +1
Query: 6721 ILLTTKTETPSSIAVDPVSRYLYWADQG-QKPTIQRSFLDGSRREVIVSSGIAEPTDLVV 6897
++ ++ + P +A+D ++W + Q P+I R+ L G V+VS+ I P L +
Sbjct: 66 VITMSEDDHPHVLALDECQNLMFWTNWNEQHPSIMRATLTGKNAHVVVSTDILTPNGLTI 125
Query: 6898 DVASKMIYWSDAKMDGIYRVRSTGGTPE-LVRSDIASAAGVALHGQNMYWTDNRLEKLFR 7074
D ++ +Y+SD + I R G +V+S + +A++ ++W+D + R
Sbjct: 126 DHRAEKLYFSDGSLGKIERCEYDGSQRHVIVKSGPGTFLSLAVYDNYIFWSDWGRRAILR 185
Query: 7075 ATS-KPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRASSPCQITDNLRKSPCTQLCFA 7251
+ +T +L S + +G +AV + N SPC L C LC
Sbjct: 186 SNKYTGGETKVLRSD----IPHQPMGIIAVANDTNSCEL-SPCA----LLNGGCHDLCLL 236
Query: 7252 TPGTQTPTCSCA--RGVLKGRTC 7314
TP + CSC R +L C
Sbjct: 237 TPDGRV-NCSCRGDRTLLASNRC 258
Score = 63.2 bits (152), Expect = 2e-07
Identities = 79/332 (23%), Positives = 129/332 (38%), Gaps = 16/332 (4%)
Frame = +1
Query: 2404 MSFDWISKQLYYVDNIR-----------NSLEV-VKIGETGLVHPDELVRRQLITELRDP 2547
++ DW++ +Y+ D+ R SL + +G+ L P+ R L +P
Sbjct: 1689 IAVDWVTGNVYWTDHSRMHWFSYYTTHWTSLRYSINVGQ--LNGPN--CTRLLTNMAGEP 1744
Query: 2548 VSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGD 2727
++ V+P +G++++ + I +DG +++ L RP+ + +D R+ W D
Sbjct: 1745 YAIAVNPKRGMMYWTVIGDHSHIEEAAMDGTLRRILVQKHLQRPTGLTVDHFGERIYWAD 1804
Query: 2728 TLLKTISCMDFDGKN-VVKLDIDNPI--PVAITIMNEYIYYVHQRPYSIRRVHKKNGGGS 2898
L I + +DG + VV + + P I + +YIY + I RV K G
Sbjct: 1805 FELSIIGSVMYDGSSPVVSVSSKQGLLHPHRIDVFEDYIYGAGPK-NGIFRVQKFGHGSV 1863
Query: 2899 KIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKC 3078
+++ +SI N P +PC C LC PS A C
Sbjct: 1864 EVLTLDVDKTKSIVVSHRYKQLNLP-------NPCLGLSCDFLCLLNPS-------GATC 1909
Query: 3079 ACRQGFMINKENNHSCQKDPAEKIEQLCSSNSTQFQCKN-GRCIPKEWKCDGENDCLDES 3255
C +G I H E +S + C+N GRCI E K D C
Sbjct: 1910 VCPEGKHIRNGTCH----------ENSLLDDSCKLTCENGGRCILNE-KGDLRCHCWP-- 1956
Query: 3256 DEIDEKGDKCFHETECAENTIKCRNTKKCIPA 3351
G +C E + C+N CIP+
Sbjct: 1957 ---SYSGGRC----EVNHCSNYCQNGGTCIPS 1981
Score = 60.8 bits (146), Expect = 9e-07
Identities = 43/177 (24%), Positives = 76/177 (42%), Gaps = 11/177 (6%)
Frame = +1
Query: 5875 VARAGLDGSNPLVIASNDLAELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSD 6054
+ RA L G N V+ S D+ + + ID ++YFS+ G+I YDG RH ++
Sbjct: 99 IMRATLTGKNAHVVVSTDILTPNGLTIDHRAEKLYFSDGSLGKIERCEYDGSQRHVIVKS 158
Query: 6055 GGRQPNGLAFYGDRLFYADSAFDSIEVAT--INGDSQPPQWTHFKKDV--ENLANIKALQ 6222
G LA Y + +F++D +I + G+++ + D+ + + I
Sbjct: 159 GPGTFLSLAVYDNYIFWSDWGRRAILRSNKYTGGETKV-----LRSDIPHQPMGIIAVAN 213
Query: 6223 PRASSSGHPCHINNGNCDHICIPLMFAQRTCTC-------ANGYVKDGQTSCKLFDE 6372
S PC + NG C +C+ + C+C A+ +SC ++ E
Sbjct: 214 DTNSCELSPCALLNGGCHDLCLLTPDGRVNCSCRGDRTLLASNRCVTKNSSCNIYSE 270
Score = 56.2 bits (134), Expect = 2e-05
Identities = 49/215 (22%), Positives = 87/215 (39%), Gaps = 10/215 (4%)
Frame = +1
Query: 13057 HAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTT 13236
H I A + G + ++V + +P + ID + ++Y+ D +++ DGS+R
Sbjct: 96 HPSIMRATLTGKNAHVVVSTDILTPNGLTIDH-RAEKLYFSDGSLGKIERCEYDGSQRHV 154
Query: 13237 VVHDRHIPY-AVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYA 13413
+V + ++ V++N+I+W + + +K+ G VL SD+ H A
Sbjct: 155 IVKSGPGTFLSLAVYDNYIFWSDWGRRAILRSNKYTGGETKVLRSDIP--HQPMGIIAVA 212
Query: 13414 KDTQR-TVSGCE--RAQCSHLCVSLPSTGFACLCPDGIVPQLDGSCATQHVEALTMPKQC 13584
DT +S C C LC+ P C C C T++ + + +
Sbjct: 213 NDTNSCELSPCALLNGGCHDLCLLTPDGRVNCSCRGDRTLLASNRCVTKN-SSCNIYSEF 271
Query: 13585 KCTNGG------KCRLDGSCECTSDFEGDQCEKES 13671
+C NG C C+ SD + CE S
Sbjct: 272 ECGNGDCVDYVLTCDGIPHCKDKSDEKLLYCENRS 306
Score = 56.2 bits (134), Expect = 2e-05
Identities = 36/127 (28%), Positives = 58/127 (45%), Gaps = 1/127 (0%)
Frame = +1
Query: 1621 MDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVP 1800
MDGTN+ ++ T + + +D R+YW D + +E + G+ R V +P
Sbjct: 893 MDGTNQSVVIETKISRPMALTIDYVNHRLYWADE--NHIEFSNMDGSHRHKVPN--QDIP 948
Query: 1801 HPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQP-GP 1977
L LF+ Y+YWTD + +V K +L + + + I YH QP GP
Sbjct: 949 GVIALTLFEDYIYWTDGKTKSLSRVHKTSGADRLSLIYSWHAI--TDIQVYHSYRQPDGP 1006
Query: 1978 GQSECLA 1998
G++ A
Sbjct: 1007 GKTHTCA 1013
Score = 38.5 bits (88), Expect = 4.9
Identities = 39/191 (20%), Positives = 70/191 (36%), Gaps = 10/191 (5%)
Frame = +1
Query: 13432 VSGCERAQCSHLCVSLPSTGFACLCPDGIVPQLDGSCATQHVEALTMPKQCK--CTNGGK 13605
+ C R H ++ + C C +G ++ SC + C C NGG
Sbjct: 2073 IDKCVRCHGGHCIINQDNEDIFCNCTNG---KIASSC-----------QLCDGYCYNGGT 2118
Query: 13606 CRLDGS-----CECTSDFEGDQCEKESSVSRKIIGTLSENFITVXXXXXXXXXXXXXXXX 13770
C+LD C C++++ G QCE+ + S K + + +
Sbjct: 2119 CQLDPETSVPVCVCSTNWSGTQCERPAPKSSKSEHISTRSIAIIVPLVLLVTLVTTLVIG 2178
Query: 13771 XXXNLYKRRQLLFKKNEAADGSVSFHGNVISFSNPVLENKQ-DAPGSEFNMQQMTSMHD- 13944
KRR ++ +G ++ + NP + D S+ + + + M D
Sbjct: 2179 LVVCKRKRRTKTIRRQPIINGGIN-----VEIGNPSYNMYEVDHDHSDGGLLEPSFMIDP 2233
Query: 13945 -DSTTFTNPVY 13974
T ++NPVY
Sbjct: 2234 VKPTNYSNPVY 2244
Score = 37.7 bits (86), Expect = 8.3
Identities = 45/205 (21%), Positives = 80/205 (38%), Gaps = 21/205 (10%)
Frame = +1
Query: 5824 KGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAIDTTNTRVYFSEAKAGR 6003
+G ++W G + + A +DG+ ++ L + +D R+Y+++ +
Sbjct: 1753 RGMMYWTVIGD---HSHIEEAAMDGTLRRILVQKHLQRPTGLTVDHFGERIYWADFELSI 1809
Query: 6004 ISSVTYDGQDRHYVLS--DGGRQPNGLAFYGDRLFYADS----------AFDSIEVATIN 6147
I SV YDG +S G P+ + + D ++ A S+EV T++
Sbjct: 1810 IGSVMYDGSSPVVSVSSKQGLLHPHRIDVFEDYIYGAGPKNGIFRVQKFGHGSVEVLTLD 1869
Query: 6148 GDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHINNGNCDHICIPLMFAQRTCTCAN 6327
D + NL N PC +CD +C+ L + TC C
Sbjct: 1870 VDKTKSIVVSHRYKQLNLPN-------------PC--LGLSCDFLCL-LNPSGATCVCPE 1913
Query: 6328 G-YVKDG--------QTSCKLFDES 6375
G ++++G SCKL E+
Sbjct: 1914 GKHIRNGTCHENSLLDDSCKLTCEN 1938
>gi|47228667|emb|CAG07399.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 2304
Score = 874 bits (2259), Expect = 0.0
Identities = 690/2434 (28%), Positives = 1087/2434 (44%), Gaps = 136/2434 (5%)
Frame = +1
Query: 544 CFQYQFRCADKTQCIQKSWVCDGSKDCADGSDE-PDTCEFKK---CTANEFQCKNKR-CQ 708
C QF C D+ CI K W CDG KDC DGSDE PD C K C NE C + C
Sbjct: 8 CSSKQFVCKDQVTCISKGWRCDGEKDCPDGSDESPDICSHSKVNQCPVNEHGCLDPEVCI 67
Query: 709 PRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQ 888
P CD DC D DE HC +Q C +
Sbjct: 68 PMSRLCDGVPDCTDGWDEGP-----------------HCREQAPACIAQR---------- 100
Query: 889 CSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHR 1068
CQ C + G C C +GY++ RTC D NEC +G C Q C+N
Sbjct: 101 ----------CQFNCSVTHDGPRCYCSAGYEV-TADGRTCKDFNECNVYGTCSQTCSNTE 149
Query: 1069 PGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEE 1248
+TCSC+ + + LQ DN + C + N +L + L+ +
Sbjct: 150 GSYTCSCV-EGYLLQ------PDNRS----CKAKNDPVDRLPMLLIANLHDIRCTTLSGA 198
Query: 1249 VKKL--ASGEFIYGIDFDYGDRKIFWTD----RLAHSAFSADVDDEGEISQIKKLSLK-S 1407
+ +L + + +DF Y D + W D A A + D ++ I+ +++ S
Sbjct: 199 LSRLHAITTKQTMAMDFIYADETVCWIDVGETPAATHLKCASIPDLKTVTNIRTINITLS 258
Query: 1408 LVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMF 1587
L + +A+DW+T Y ++ R+ V + DG+ LL L P IALDP G++F
Sbjct: 259 LHHVEQMAIDWLTKNFYFVDDVDDRVFVCNKDGQTCVTLLDQDLYNPKGIALDPAMGKVF 318
Query: 1588 FT---NQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQG 1758
FT + ++E MDG NR LV+T GI +D+ + VYW D +D +E +DY+G
Sbjct: 319 FTDYGSTPRVERCDMDGQNRTKLVDTKIVFPHGITLDLVNRLVYWADAYLDYIEVVDYEG 378
Query: 1759 NDRRIVAQGMNVVPHPFGLALFDQYLYWTDW------TRLGVIQVEKFGSDTKLLWSNTE 1920
+R + QG+ ++ H +GL +F+ YLY T+ + VI+V +F S + + +
Sbjct: 379 KNRHTIIQGL-LIEHLYGLTVFENYLYATNSDEGNLNPKTSVIRVNRFNSSDFQVVTRVD 437
Query: 1921 NNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACP 2100
+ YH QP C + C +C+LS + C C
Sbjct: 438 RGA---ALHVYHQRRQPQVRSHACTTDQFGKA---GGCSDICLLSNSH----KTRTCRCR 487
Query: 2101 IGQKL-VNGKRC--IDSIDYLLFSSNK--IVRGIFPEINEKALAEAVLPISPISQRRIGM 2265
G L +GK C D +L++ + I+RG+ ++N K E ++PI + R
Sbjct: 488 SGFSLGSDGKSCKKPDHELFLVYGKGRPGIIRGM--DMNAKVPDEYMIPIENLMNPR--- 542
Query: 2266 YFEVECDVHGNS--FFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWISKQLYY 2439
D H S ++AD I R + DG +L + ++ DW+ LY+
Sbjct: 543 ----ALDFHAASEYIYFADATSYIIGRQKIDGTERDTILKEGIHTVEGIAVDWMGGNLYW 598
Query: 2440 VDN-IRNSLEVVKIGETGLVHPDELVRRQLIT-ELRDPVSVVVHPWKGLLFYAE------ 2595
D+ + ++ V ++ + R+ LI ++ P ++VV P G +++ +
Sbjct: 599 TDDGPKKTISVARLEKA------SQTRKTLIEGKMSHPRAIVVDPQHGWMYWTDWEEDPS 652
Query: 2596 AMRPAAIYRCHIDGQNCQV-IRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCM------ 2754
I + +DG + Q+ + + T+ P+ +++D + L W D I +
Sbjct: 653 ESNRGKIKKAWMDGSHHQIFLTSKTVLWPNGLSLDIPQGILYWVDAYYDRIEMVYLNTTE 712
Query: 2755 --------------------------DFDGKNVVKLDIDNPIPVAITIMNEYIYYVHQRP 2856
++ G ++ KLD + +T++ ++RP
Sbjct: 713 RKVVYEGQELTHAFGLCHYKQFLFWNEYRGGSIYKLD---QVTKTVTLLR------NERP 763
Query: 2857 --YSIR--RVHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQ--C 3018
+ IR H++ G + R F E S S P + CR + C
Sbjct: 764 PIFEIRVYDAHQQQGSSASHTRPFRTGENMSDSFIPGS------PFGLGSNACRVNNGGC 817
Query: 3019 TQLCFATPSESHPNELEAKCACRQGFMINKENNHSCQKDPAEKIEQLCSSNSTQFQCKNG 3198
+ LC A P C C +++ + N +C+ +P+ C +F CKN
Sbjct: 818 SSLCLAIPD-------GRSCGCADDQILDGD-NVTCKANPSYVNPPQCQPG--EFACKNN 867
Query: 3199 RCIPKEWKCDGENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKKCIPAQXXXXXXXX 3378
RCI + WKCDG+NDCLD SDE E H+ C + KC+N +CIP +
Sbjct: 868 RCIQERWKCDGDNDCLDNSDEAPE----LCHQHTCPADRFKCQN-NRCIPLRWLCDGDND 922
Query: 3379 XXXXXXXXVKYCKDGQKPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCGN-- 3552
C C ++ C + RCIP W E + CG
Sbjct: 923 CGNDEDESNTTC---SARTCPPNQYPCASGRCIPISWTCDLDDDCGDRSDEP-DSCGELV 978
Query: 3553 --ATCAAN------------------------QFSCANGRCIPIYWLCDGDNDCYDGTDE 3654
+ C+++ QF+CANGRCI I W CD DNDC D +DE
Sbjct: 979 APSRCSSSVRLFCFHISPLDPPSAYPTCFPLTQFTCANGRCININWRCDNDNDCGDNSDE 1038
Query: 3655 DKERCPPVQCSALQFRCANGRQCVPL------RNHXXXXXXXXXXXXXXXXAVTAESCTP 3816
C CS++QF+C +GR C+P N C
Sbjct: 1039 --AGCSH-SCSSVQFKCNSGR-CIPEYWTCDGDNDCGDYSDETHANCTNQATRPPGGCHV 1094
Query: 3817 DQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKC-GNGRCILNNWL 3993
D+F+C LCIP W+ SDE + + +F C + RCI W+
Sbjct: 1095 DEFQCRMDSLCIPMRWRCDGDTDCMDLSDERNCEGVTHMCDPAVKFSCKDSARCISKAWV 1154
Query: 3994 CDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTD 4173
CDG++DC D SDE + +A C H C + C+P +LCDG CP G+D
Sbjct: 1155 CDGDSDCEDNSDED-------NCDALVCKLSHHTCATNDSICLPAEKLCDGTDDCPDGSD 1207
Query: 4174 EGGRCARDLCSADRAGCSFKCHNSP-NGPICSCPFGEQL--VNKTKCEPENECLDSSSCS 4344
E DLC+ D GCS C P G +CSCP G +L NKT C+ ++ C CS
Sbjct: 1208 EK---LCDLCALDNGGCSHNCTIIPGEGFMCSCPLGMELGADNKT-CQIQSFCAKHLKCS 1263
Query: 4345 QRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFG 4524
Q+C+ EK CSC EG+EL+ D +CK D K I+ SNR+ I D +
Sbjct: 1264 QKCEQEKSSVKCSCYEGWELEADMESCKSTDPFKPFIIF-SNRHEIRRIDLHKGEFSVLV 1322
Query: 4525 AIVENAIALAWDSLTDRIYWSDIREKKI----LSANRNGTNATVFIADGLDITEGIALDW 4692
+ N IAL + +YW+D+ E KI LS N T+ V I GL EG+A+DW
Sbjct: 1323 PGLRNTIALDFHLSESTLYWTDVVEDKIYRGKLSENGALTSFEVVIQYGLATPEGLAVDW 1382
Query: 4693 VGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQN-PC 4869
+ N+YWV+S+L+ IEVA L D RT L+ V PR IA+DPR G++FWTDW + P
Sbjct: 1383 IAGNIYWVESNLDQIEVAKL-DGTMRTTLLAGEVEHPRAIALDPRDGILFWTDWDASLPR 1441
Query: 4870 IERASMDGTDRQIIVKT--KIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVL 5043
IE ASM G R+ I + WPN + +DY R+ + D++ D I YDGSG +VL
Sbjct: 1442 IEAASMSGEGRRTIHRETGSGGWPNGLTVDYMERRIVWIDARSDAIYSAMYDGSGLIEVL 1501
Query: 5044 ASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPV 5223
+++ HP A+ ++ +Y++D R L K+ G T ++ + HP
Sbjct: 1502 RGHEYLSHPFAVTMYGGEVYWTDWRTNTLAKANKW-TGHNVTVVQRTNTQPFDLQVYHPS 1560
Query: 5224 LQPVIKNNPCSTNPCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNV 5403
QP NPC+++PCSHLCL+N TF+C CP KL + C +++ FL+ ++ +
Sbjct: 1561 RQPKAP-NPCASSPCSHLCLINFNQTFSCACPHLMKLQPDKRTC-KESRKFLLYARQIEI 1618
Query: 5404 FGIEMNSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSA 5583
G+++++ +++ VP + N YDA+ ++ + + T +
Sbjct: 1619 RGVDIDNPYYNY--IISFTVP--DIDNVTAVDYDAVEHRIY----------WSDVRTQT- 1663
Query: 5584 IYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRNL----VVGNKITQTIEIIRTQGKQYR 5751
I R+ +NG + S+ +P +A+ L DW RNL NK + I + R G
Sbjct: 1664 IKRAFINGTGVETVVSADLP-NAHGLAVDWVSRNLFWTSYDANK--KQINVARLDGSFKN 1720
Query: 5752 SVILSNDQSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDL 5931
+VI D+ G ++W D ++ A +DGSN + +
Sbjct: 1721 AVIQGLDKPHCLVLHPIL-------GKLYWTD------GDNISMANMDGSNHTTLFTGQK 1767
Query: 5932 AELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGR--QPNGLAFYGDRLFY 6105
+ ++ID ++Y+ + G IS DG + G+ + LA GD+L++
Sbjct: 1768 GPVG-LSIDYEKDQLYWISSGNGTISRCQLDGTKLEIMEGVKGKLSKATALAIMGDKLWW 1826
Query: 6106 ADSAFDSIEVATINGDSQPPQWTHFKKDVENLANIKALQPRASSSG-HPCHINNGNCDHI 6282
AD D I W + + + +++ A SG + C NNG+C +
Sbjct: 1827 ADQGSDQIGTC---DKKDGGNWKVMRNNTSPMMHMRIYDESAQKSGINLCSNNNGDCSQL 1883
Query: 6283 CIPLMFAQRTCTCANGY-VKDGQTSCKLFDESFVIVATKTKVIGYPIDETQSKGVAMEPI 6459
C+P R C C GY +K GQ SC+ SF++ + + G P+D K A+ P+
Sbjct: 1884 CLPTSPTTRACMCTAGYSLKSGQQSCEGMG-SFLLFSVHEGIRGIPLDPA-DKSDALVPV 1941
Query: 6460 GGLSI-TGVDYDYESKTIYVAE--ASGINKGITAYTIGESSPRAVIRDSIGSLTIKSLAI 6630
G S+ G+D+ E+ TIY + S I++ T E V+ + IG ++ + +
Sbjct: 1942 SGTSLAVGIDFHAENDTIYWVDMGLSTISRAKRDQTWRED----VVTNGIG--RVEGITV 1995
Query: 6631 DWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQK 6810
DWI N+Y+ + + IEV++L+G++R ++++ + P +I V P YL+W + GQ
Sbjct: 1996 DWIAGNIYWTDQGFD--VIEVARLNGSFRYVVISQGLDKPRAITVHPSKGYLFWTEWGQY 2053
Query: 6811 PTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVR-STGGTPELV 6987
P I+RS LDGS+R V+V+ I+ P + +D ++YW DA+ D I R+ TG ELV
Sbjct: 2054 PRIERSRLDGSQRLVLVNVSISWPNGISIDYEEGLLYWCDARTDKIERINLETGENRELV 2113
Query: 6988 -RSDIASAAGVALHGQNMYWTD-NRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAV 7161
++ V++ +++YW+D + SK N T + T + LKDI V
Sbjct: 2114 LANNNMDMFAVSVFEEHIYWSDRTHANGSIKRGSKDNATDAVQLRTGIGVQLKDI---KV 2170
Query: 7162 FSSNNQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCARGVL--KGRTCEEPDTYI 7335
F+ Q + ++ C+ + C QLC G TC+CA G+L R+C + D Y+
Sbjct: 2171 FNKARQ-QGTNVCRNNN----GGCEQLCLYR-GNGERTCACAHGMLAEDNRSCRDYDGYL 2224
Query: 7336 MFSDGDKIIDVAIEPDVKASRPLKDPFPEISNLQ 7437
++S+ + + + + + P+K PF + +++
Sbjct: 2225 LYSERTILKSIHLSDETNLNAPIK-PFEDPDHMK 2257
Score = 426 bits (1095), Expect = e-117
Identities = 269/821 (32%), Positives = 392/821 (46%), Gaps = 43/821 (5%)
Frame = +1
Query: 8539 IDSAKKCNHIDDCGDGSDELDC---PSAV---ACAEGTFPCSNGHCINQTKVCDGHNDCH 8700
I + C DD D + C PS V C G F C N CI + CDG NDC
Sbjct: 824 IPDGRSCGCADDQILDGDNVTCKANPSYVNPPQCQPGEFACKNNRCIQERWKCDGDNDCL 883
Query: 8701 DEQVSDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQ 8880
D SDE+ C C + +C N N CI LCDG +DCG+ DE+ C +
Sbjct: 884 DN--SDEAPELCH--QHTCPADRFKCQN-NRCIPLRWLCDGDNDCGNDEDESNTTCSART 938
Query: 8881 CAQHYVRCPSGRCIPETWQCDGDNDCSDGWDE--------THTNCTDT------------ 9000
C + C SGRCIP +W CD D+DC D DE + C+ +
Sbjct: 939 CPPNQYPCASGRCIPISWTCDLDDDCGDRSDEPDSCGELVAPSRCSSSVRLFCFHISPLD 998
Query: 9001 --AGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTS 9174
+ C F C N +CI+ I GC + +C+ +F C S
Sbjct: 999 PPSAYPTCFPLTQFTCANGRCIN---INWRCDNDNDCGDNSDEAGC-SHSCSSVQFKCNS 1054
Query: 9175 NAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKE----CNKGEFRC-SNQHCI 9339
CIP W CDGD C DE+ C + C+ EF+C + CI
Sbjct: 1055 G--------RCIPEYWTCDGDNDCGDYSDETHANCTNQATRPPGGCHVDEFQCRMDSLCI 1106
Query: 9340 HSTWECDGDNDCLDGSDEHANC--TYSSCQPDF-FQCANH-KCVPNSWKCDGNDDCEDGS 9507
W CDGD DC+D SDE NC C P F C + +C+ +W CDG+ DCED S
Sbjct: 1107 PMRWRCDGDTDCMDLSDER-NCEGVTHMCDPAVKFSCKDSARCISKAWVCDGDSDCEDNS 1165
Query: 9508 DEKDCPKNSASAQKASKCSNGQFQCTSGE--CIDDAKVCDRNFDCTDRSDESSLCFIDEC 9681
DE +C A C C + + C+ K+CD DC D SDE LC D C
Sbjct: 1166 DEDNC--------DALVCKLSHHTCATNDSICLPAEKLCDGTDDCPDGSDE-KLC--DLC 1214
Query: 9682 SLAEKPLCEQKCMDMK-IGYKCDCFEGFAIDISDQKSCHNVNECYEGISGCSQKCDDKIG 9858
+L + C C + G+ C C G + +D K+C + C + + CSQKC+ +
Sbjct: 1215 AL-DNGGCSHNCTIIPGEGFMCSCPLGMELG-ADNKTCQIQSFCAKHLK-CSQKCEQEKS 1271
Query: 9859 SYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYELAAQGFDNVVS 10038
S KC C +G++L +D SCK T+ +PF + +N+H IR+I + ++ + G N ++
Sbjct: 1272 SVKCSCYEGWELEADMESCKSTD-PFKPFIIFSNRHEIRRIDLHKGEFSVLVPGLRNTIA 1330
Query: 10039 LDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYM 10218
LD L+E Y D + ++ R L E + L+S+E V+++ + EG+AVDW+ +Y
Sbjct: 1331 LDFHLSESTLYWTDVVEDKIYRGKLSE-NGALTSFEVVIQYGLATPEGLAVDWIAGNIYW 1389
Query: 10219 LNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFFTEWSLQ-PYIGRIALDG 10395
+ I V +LDG TL+ ++ P+AI + P G LF+T+W P I ++ G
Sbjct: 1390 VESNLDQIEVAKLDGTMRTTLLAGEVEHPRAIALDPRDGILFWTDWDASLPRIEAASMSG 1449
Query: 10396 SPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHI--PAQR 10569
E + I + GWPN + +DY R+ W DA + I +DG+G + +
Sbjct: 1450 --EGRRTIHRETGSG-GWPNGLTVDYMERRIVWIDARSDAIYSAMYDGSGLIEVLRGHEY 1506
Query: 10570 TSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDLRIVHPMRQPAYP 10749
SH ++ ++ +YW DW + + +KWTG N T++++T P DL++ HP RQP P
Sbjct: 1507 LSHPFAVTMYGGEVYWTDWRTNTLAKANKWTGHNVTVVQRTNTQPFDLQVYHPSRQPKAP 1566
Query: 10750 NPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTCE 10872
NPC + CSHLCLI ++C+CP L D++TC+
Sbjct: 1567 NPCA--SSPCSHLCLINF-NQTFSCACPHLMKLQPDKRTCK 1604
Score = 350 bits (899), Expect = 4e-94
Identities = 279/977 (28%), Positives = 429/977 (43%), Gaps = 35/977 (3%)
Frame = +1
Query: 304 YTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDG 483
+T + CI RCDN DC D SDE C S CSS F C GR C CDG
Sbjct: 1012 FTCANGRCININWRCDNDNDCGDNSDEAGCSHS---CSSVQ-FKCNSGR-CIPEYWTCDG 1066
Query: 484 KYDCRDLSDEKDS-CSRNHT----ACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPD 648
DC D SDE + C+ T C +F+C + CI W CDG DC D SDE +
Sbjct: 1067 DNDCGDYSDETHANCTNQATRPPGGCHVDEFQCRMDSLCIPMRWRCDGDTDCMDLSDERN 1126
Query: 649 TCE--FKKCT-ANEFQCKNK-RCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGT 816
CE C A +F CK+ RC + + CD DC DNSDED C C C
Sbjct: 1127 -CEGVTHMCDPAVKFSCKDSARCISKAWVCDGDSDCEDNSDEDNCDALVCKLSHHTCATN 1185
Query: 817 GH-CIDQLKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSP-HGGECTCPSGYKLDD 990
C+ KLCDG+ DC DG+DE+ C + GC C P G C+CP G +L
Sbjct: 1186 DSICLPAEKLCDGTDDCPDGSDEKLCDLCALDNGGCSHNCTIIPGEGFMCSCPLGMELGA 1245
Query: 991 RFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSN 1170
++TC + CA+ C Q C + CSC + + L+ + K + + + +
Sbjct: 1246 D-NKTCQIQSFCAKHLKCSQKCEQEKSSVKCSCY-EGWELEADMESCKSTDPFKPFIIFS 1303
Query: 1171 NADKMKLFVARREGLYRLNPKNPDEEVKKLASG-EFIYGIDFDYGDRKIFWTDRLAHSAF 1347
N ++ RR L++ E L G +DF + ++WTD + +
Sbjct: 1304 NRHEI-----RRIDLHK-------GEFSVLVPGLRNTIALDFHLSESTLYWTDVVEDKIY 1351
Query: 1348 SADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLL 1527
+ + G ++ + + L P LAVDWI +Y +ES +I+V+ DG RT LL
Sbjct: 1352 RGKLSENGALTSFEVVIQYGLATPEGLAVDWIAGNIYWVESNLDQIEVAKLDGTMRTTLL 1411
Query: 1528 ADGLTLPLDIALDPLRGEMFFT----NQLKLEAAAMDGTNRRTLVNTHTHQ---VSGIVV 1686
A + P IALDP G +F+T + ++EAA+M G RRT ++ T +G+ V
Sbjct: 1412 AGEVEHPRAIALDPRDGILFWTDWDASLPRIEAASMSGEGRRT-IHRETGSGGWPNGLTV 1470
Query: 1687 DITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGV 1866
D +R+ W+D + D + S Y G+ V +G + HPF + ++ +YWTDW +
Sbjct: 1471 DYMERRIVWIDARSDAIYSAMYDGSGLIEVLRGHEYLSHPFAVTMYGGEVYWTDWRTNTL 1530
Query: 1867 IQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMC 2046
+ K+ + T N P + YHP QP K NPC ++ C +C
Sbjct: 1531 AKANKWTGHNVTVVQRT--NTQPFDLQVYHPSRQP----------KAPNPCASSPCSHLC 1578
Query: 2047 ILSKDNGGFGVGYKCACPIGQKLVNGKR-CIDSIDYLLFSSNKIVRGIFPEINEKALAEA 2223
+++ F + CACP KL KR C +S +LL++ +RG+ +I+
Sbjct: 1579 LIN-----FNQTFSCACPHLMKLQPDKRTCKESRKFLLYARQIEIRGV--DIDNPYYNYI 1631
Query: 2224 VLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFS 2403
+ P I V+ D + +++D+ TI R +G G V+
Sbjct: 1632 ISFTVP----DIDNVTAVDYDAVEHRIYWSDVRTQTIKRAFINGTGVETVVSADLPNAHG 1687
Query: 2404 MSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKGLL 2583
++ DW+S+ L++ N ++ + D + +I L P +V+HP G L
Sbjct: 1688 LAVDWVSRNLFWTSYDANKKQI------NVARLDGSFKNAVIQGLDKPHCLVLHPILGKL 1741
Query: 2584 FYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFD 2763
++ + I ++DG N + G P ++ID+ +++L W + TIS D
Sbjct: 1742 YWTDGDN---ISMANMDGSNHTTLFTGQKG-PVGLSIDYEKDQLYWISSGNGTISRCQLD 1797
Query: 2764 GKNVVKLDIDNPI------PVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGA- 2922
G KL+I + A+ IM + +++ Q I KK+GG K++R +
Sbjct: 1798 G---TKLEIMEGVKGKLSKATALAIMGDKLWWADQGSDQIGTCDKKDGGNWKVMRNNTSP 1854
Query: 2923 -------DERSIFS-LKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKC 3078
DE + S + CS+ N C+QLC T + C
Sbjct: 1855 MMHMRIYDESAQKSGINLCSNNN--------------GDCSQLCLPTSPTTR------AC 1894
Query: 3079 ACRQGFMINKENNHSCQ 3129
C G+ + K SC+
Sbjct: 1895 MCTAGYSL-KSGQQSCE 1910
Score = 301 bits (772), Expect = 2e-79
Identities = 225/766 (29%), Positives = 331/766 (42%), Gaps = 89/766 (11%)
Frame = +1
Query: 9826 GCSQKC--DDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDG-- 9993
GCS C + + C C G+ L SD SCK+ + E + IR + ++
Sbjct: 468 GCSDICLLSNSHKTRTCRCRSGFSLGSDGKSCKKPDHELFLVYGKGRPGIIRGMDMNAKV 527
Query: 9994 -NKYELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNVY 10170
++Y + + N +LD + Y D + R +D + +T+L+ ++
Sbjct: 528 PDEYMIPIENLMNPRALDFHAASEYIYFADATSYIIGRQKIDGTER-----DTILKEGIH 582
Query: 10171 GTEGIAVDWVGRKLYMLNR-QERSIRVCELD--GRFCKTLIRDRIQQPKAIVVHPGKGYL 10341
EGIAVDW+G LY + +++I V L+ + KTLI ++ P+AIVV P G++
Sbjct: 583 TVEGIAVDWMGGNLYWTDDGPKKTISVARLEKASQTRKTLIEGKMSHPRAIVVDPQHGWM 642
Query: 10342 FFTEWSLQP------YIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDA 10503
++T+W P I + +DGS IF L + WPN +++D L+W DA
Sbjct: 643 YWTDWEEDPSESNRGKIKKAWMDGS---HHQIF-LTSKTVLWPNGLSLDIPQGILYWVDA 698
Query: 10504 HLNEIGFMDFDGNGRRHI-PAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETI 10680
+ + I + + R+ + Q +H + + +L+W ++ + + D+ T K T+
Sbjct: 699 YYDRIEMVYLNTTERKVVYEGQELTHAFGLCHYKQFLFWNEYRGGSIYKLDQVT-KTVTL 757
Query: 10681 LKKTVQLPNDLRIVHPMRQ----------------------PAYP-----NPCGDNNGGC 10779
L+ ++R+ +Q P P N C NNGGC
Sbjct: 758 LRNERPPIFEIRVYDAHQQQGSSASHTRPFRTGENMSDSFIPGSPFGLGSNACRVNNGGC 817
Query: 10780 SHLCLIGAGGNGYTCSCPDQFVLLSDQKTCE--------PNCTERQFACGGDDAKCIPKL 10935
S LCL A +G +C C D +L D TC+ P C +FAC + +CI +
Sbjct: 818 SSLCL--AIPDGRSCGCADDQILDGDNVTCKANPSYVNPPQCQPGEFACKNN--RCIQER 873
Query: 10936 WYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXXEQNC 11115
W CDG+ DC D SDE E +C Q CP F+C N+ C + E N
Sbjct: 874 WKCDGDNDCLDNSDEAPE-LCHQHTCPADRFKCQNNRCIPLRWLCDGDNDCGNDEDESNT 932
Query: 11116 D---KACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEADTL--------CMSAER--- 11253
+ C P + C A+GRCIP +T RSDE D+ C S+ R
Sbjct: 933 TCSARTCPPNQYPC-ASGRCIPISWTCDLDDDCGDRSDEPDSCGELVAPSRCSSSVRLFC 991
Query: 11254 -------------NC-TAEEFRCNNNKCIAKAWRXXXXXXXXXXXXETPECAQIECKKGW 11391
C +F C N +CI WR E C+ C
Sbjct: 992 FHISPLDPPSAYPTCFPLTQFTCANGRCININWRCDNDNDCGDNSDEA-GCSH-SCSSVQ 1049
Query: 11392 TRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRC-------PTCDDVGEFRCATSGKCIPR 11550
+C+S RCIP + C+G +DC D SDE C P V EF+C CIP
Sbjct: 1050 FKCNSG-RCIPEYWTCDGDNDCGDYSDETHANCTNQATRPPGGCHVDEFQCRMDSLCIPM 1108
Query: 11551 RWMCDTENDCGDNSDELDASCGGTTRPCSES-EFRCND-GKCIPGSKVCDGTIQCSDGLD 11724
RW CD + DC D SDE +C G T C + +F C D +CI + VCDG C D D
Sbjct: 1109 RWRCDGDTDCMDLSDE--RNCEGVTHMCDPAVKFSCKDSARCISKAWVCDGDSDCEDNSD 1166
Query: 11725 ESQCTLRRCLPGHRQC--DDGTCIAEHKWCDRKKDCPNAADELHCE 11856
E C C H C +D C+ K CD DCP+ +DE C+
Sbjct: 1167 EDNCDALVCKLSHHTCATNDSICLPAEKLCDGTDDCPDGSDEKLCD 1212
Score = 291 bits (744), Expect = 4e-76
Identities = 254/1001 (25%), Positives = 411/1001 (40%), Gaps = 104/1001 (10%)
Frame = +1
Query: 6613 IKSLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYW 6792
++ +AIDW+ N YF++ +R + V DG LL P IA+DP +++
Sbjct: 262 VEQMAIDWLTKNFYFVDDVDDR--VFVCNKDGQTCVTLLDQDLYNPKGIALDPAMGKVFF 319
Query: 6793 ADQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGG 6972
D G P ++R +DG R +V + I P + +D+ ++++YW+DA +D I V G
Sbjct: 320 TDYGSTPRVERCDMDGQNRTKLVDTKIVFPHGITLDLVNRLVYWADAYLDYIEVVDYEGK 379
Query: 6973 TPELVRSD--IASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDI 7146
+ I G+ + +Y T++ L TS S V +
Sbjct: 380 NRHTIIQGLLIEHLYGLTVFENYLYATNSDEGNLNPKTSVIRVNRFNSSDFQVVTRVDRG 439
Query: 7147 GDVAVFSSNNQPRASSPCQITDNLRKSP-CTQLCFATPGTQTPTCSCARGVL---KGRTC 7314
+ V+ QP+ S TD K+ C+ +C + +T TC C G G++C
Sbjct: 440 AALHVYHQRRQPQVRSHACTTDQFGKAGGCSDICLLSNSHKTRTCRCRSGFSLGSDGKSC 499
Query: 7315 EEPD--TYIMFSDGDKIIDVAIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVES 7488
++PD ++++ G I ++ + K P + N + D +YF +
Sbjct: 500 KKPDHELFLVYGKGRPGIIRGMDMNAKVPDEYMIPIENLMNPRALDFHAASEYIYFADAT 559
Query: 7489 PVGVNISWFSMNNAENPRLVFGASKQPHAKE-IRHISDMKLDWLTQKIYFTTGRGGKVMA 7665
+ + + G + KE I + + +DW+ +Y+T K ++
Sbjct: 560 SYIIG-----------RQKIDGTERDTILKEGIHTVEGIAVDWMGGNLYWTDDGPKKTIS 608
Query: 7666 I---DTAGEHLSTIASGDWTY--ALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGG 7830
+ + A + T+ G ++ A+ +DP G ++W+D S +I+++ + G
Sbjct: 609 VARLEKASQTRKTLIEGKMSHPRAIVVDPQHGWMYWTDWEEDPSES-NRGKIKKAWMDGS 667
Query: 7831 SRKV-IVSESISLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGYR---AKS 7998
++ + S+++ P +++D +YW D IE+ + RKV+ G A
Sbjct: 668 HHQIFLTSKTVLWPNGLSLDIPQGILYWVDAYYDRIEMVYLNTTERKVVYEGQELTHAFG 727
Query: 7999 LDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVSDRRIP-GALRVFASESD--------- 8148
L + ++L+ ++ ++++D+ + + ++ + R P +RV+ +
Sbjct: 728 LCHYKQFLFWNEYRGGSIYKLDQVTKT--VTLLRNERPPIFEIRVYDAHQQQGSSASHTR 785
Query: 8149 -VRTRNQVCNA--------LTSQLCKTDNGGCDQLCTVV--------ADDIGLAASKVQC 8277
RT + ++ L S C+ +NGGC LC + ADD L V C
Sbjct: 786 PFRTGENMSDSFIPGSPFGLGSNACRVNNGGCSSLCLAIPDGRSCGCADDQILDGDNVTC 845
Query: 8278 SCNDTY----------------ELVQEPGK-DYPTQCVLRGSNSEPAKECL-----PPYN 8391
N +Y +QE K D C+ NS+ A E P
Sbjct: 846 KANPSYVNPPQCQPGEFACKNNRCIQERWKCDGDNDCL---DNSDEAPELCHQHTCPADR 902
Query: 8392 FQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHID 8571
F+C + CI L CD DC + DE+ C+ R+CP + C + RCI + C+ D
Sbjct: 903 FKCQNNRCIPLRWLCDGDNDCGNDEDESNTTCSARTCPPNQYPCASGRCIPISWTCDLDD 962
Query: 8572 DCGDGSDE--------------------------LDCPSAV-ACAEGT-FPCSNGHCINQ 8667
DCGD SDE LD PSA C T F C+NG CIN
Sbjct: 963 DCGDRSDEPDSCGELVAPSRCSSSVRLFCFHISPLDPPSAYPTCFPLTQFTCANGRCINI 1022
Query: 8668 TKVCDGHNDCHDEQVSDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKA 8847
CD NDC D SDE+ G C V+ +C N+ CI CDG +DCGD +
Sbjct: 1023 NWRCDNDNDCGDN--SDEA-----GCSHSCSSVQFKC-NSGRCIPEYWTCDGDNDCGDYS 1074
Query: 8848 DENQLFCMNQQ------CAQHYVRC-PSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAG 9006
DE C NQ C +C CIP W+CDGD DC D DE NC
Sbjct: 1075 DETHANCTNQATRPPGGCHVDEFQCRMDSLCIPMRWRCDGDTDCMDLSDE--RNCEGVT- 1131
Query: 9007 KKICVGDYLFQC-DNLKCISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAK 9183
+C F C D+ +CIS+A++ C C C +N
Sbjct: 1132 -HMCDPAVKFSCKDSARCISKAWVCDGDSDCEDNS---DEDNCDALVCKLSHHTCATNDS 1187
Query: 9184 LAQPKYECIPRAWLCDGDVTCAGGEDES-TELCKTEKKECN 9303
+ C+P LCDG C G DE +LC + C+
Sbjct: 1188 I------CLPAEKLCDGTDDCPDGSDEKLCDLCALDNGGCS 1222
Score = 279 bits (713), Expect = 2e-72
Identities = 232/914 (25%), Positives = 390/914 (42%), Gaps = 61/914 (6%)
Frame = +1
Query: 3802 ESCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKCGNGRCIL 3981
++C+ QF C CI W+
Sbjct: 6 KTCSSKQFVCKDQVTCISKGWR-------------------------------------- 27
Query: 3982 NNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDGKTHCP 4161
CDGE DC DGSDES + + +N +CP C D E CIP+ +LCDG C
Sbjct: 28 ----CDGEKDCPDGSDESPDICSHSKVN--QCPVNEHGC-LDPEVCIPMSRLCDGVPDCT 80
Query: 4162 GGTDEGGRCARDLCSADRAGCSFKCHNSPNGPICSCPFG-EQLVNKTKCEPENECLDSSS 4338
G DEG C + C F C + +GP C C G E + C+ NEC +
Sbjct: 81 DGWDEGPHCREQAPACIAQRCQFNCSVTHDGPRCYCSAGYEVTADGRTCKDFNECNVYGT 140
Query: 4339 CSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKD--TRIYVSNRNRIYYSDHKLDNW 4512
CSQ C + + +TCSC EGY L D R+CK ++ D + ++N + I +
Sbjct: 141 CSQTCSNTEGSYTCSCVEGYLLQPDNRSCKAKNDPVDRLPMLLIANLHDIRCTTLSGALS 200
Query: 4513 HTFGAIVENAIALAWDSLTDRIYWSDIREKKI--------LSANRNGTN-ATVFIADGLD 4665
+ +A+ + + + W D+ E + + TN T+ I L
Sbjct: 201 RLHAITTKQTMAMDFIYADETVCWIDVGETPAATHLKCASIPDLKTVTNIRTINITLSLH 260
Query: 4666 ITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFW 4845
E +A+DW+ +N Y+VD + + V N +D + L+ Q++ P+GIA+DP G +F+
Sbjct: 261 HVEQMAIDWLTKNFYFVDDVDDRVFVCN-KDGQTCVTLLDQDLYNPKGIALDPAMGKVFF 319
Query: 4846 TDWGQNPCIERASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGS 5025
TD+G P +ER MDG +R +V TKI +P+ I LD VY+AD+ LD+I+ V+Y+G
Sbjct: 320 TDYGSTPRVERCDMDGQNRTKLVDTKIVFPHGITLDLVNRLVYWADAYLDYIEVVDYEGK 379
Query: 5026 GRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTF------ 5187
R ++ ++H + L +FE+ +Y ++ L PK + + S F
Sbjct: 380 NRHTII-QGLLIEHLYGLTVFENYLYATNSDEGNLN--PKTSVIRVNRFNSSDFQVVTRV 436
Query: 5188 SKALGVVAVHPVLQPVIKNNPCSTNP------CSHLCLLNNKN-TFTCKCPMGEKLDASG 5346
+ + H QP ++++ C+T+ CS +CLL+N + T TC+C G L + G
Sbjct: 437 DRGAALHVYHQRRQPQVRSHACTTDQFGKAGGCSDICLLSNSHKTRTCRCRSGFSLGSDG 496
Query: 5347 KKCIDDAKPFLVIIQKTN---VFGIEMNSASEKETPVLAGMVPLSGLGNAFDAAYDALSE 5517
K C ++ K + G++MN+ E M+P+ L N + A SE
Sbjct: 497 KSCKKPDHELFLVYGKGRPGIIRGMDMNAKVPDEY-----MIPIENLMNPRALDFHAASE 551
Query: 5518 EMFILEHTNHAKTLAQITTDSAIYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLV-V 5694
++ + T++ I R ++G + + + + DW G NL
Sbjct: 552 YIYFADATSY-----------IIGRQKIDGTERDTILKEGI-HTVEGIAVDWMGGNLYWT 599
Query: 5695 GNKITQTIEIIRTQ-GKQYRSVILSNDQSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADA 5871
+ +TI + R + Q R ++ S G+++W D +++
Sbjct: 600 DDGPKKTISVARLEKASQTRKTLIEGKMS-----HPRAIVVDPQHGWMYWTDWEEDPSES 654
Query: 5872 ---KVARAGLDGS-NPLVIASNDLAELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRH 6039
K+ +A +DGS + + + S + + +++D +Y+ +A RI V + +R
Sbjct: 655 NRGKIKKAWMDGSHHQIFLTSKTVLWPNGLSLDIPQGILYWVDAYYDRIEMVYLNTTERK 714
Query: 6040 YVLSDGGRQPN--GLAFYGDRLFYADSAFDSI-------EVATINGDSQPPQWTHFKKDV 6192
V+ +G + GL Y LF+ + SI + T+ + +PP + D
Sbjct: 715 -VVYEGQELTHAFGLCHYKQFLFWNEYRGGSIYKLDQVTKTVTLLRNERPPIFEIRVYDA 773
Query: 6193 ENLANIKALQPRASSSG-----------------HPCHINNGNCDHICIPLMFAQRTCTC 6321
A R +G + C +NNG C +C+ + R+C C
Sbjct: 774 HQQQGSSASHTRPFRTGENMSDSFIPGSPFGLGSNACRVNNGGCSSLCLAIPDG-RSCGC 832
Query: 6322 ANGYVKDG-QTSCK 6360
A+ + DG +CK
Sbjct: 833 ADDQILDGDNVTCK 846
Score = 272 bits (695), Expect = 2e-70
Identities = 216/795 (27%), Positives = 335/795 (41%), Gaps = 44/795 (5%)
Frame = +1
Query: 11257 CTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXETPE-CAQIECKKGWTRCSSSYRCIPNWA 11433
C EF C NN+CI + W+ E PE C Q C +C ++ RCIP
Sbjct: 857 CQPGEFACKNNRCIQERWKCDGDNDCLDNSDEAPELCHQHTCPADRFKCQNN-RCIPLRW 915
Query: 11434 FCNGQDDCRDNSDEDKQRCP--TCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDA 11607
C+G +DC ++ DE C TC ++ CA SG+CIP W CD ++DCGD SDE D
Sbjct: 916 LCDGDNDCGNDEDESNTTCSARTCPP-NQYPCA-SGRCIPISWTCDLDDDCGDRSDEPD- 972
Query: 11608 SCGGTTRP--CSES------------------------EFRCNDGKCIPGSKVCDGTIQC 11709
SCG P CS S +F C +G+CI + CD C
Sbjct: 973 SCGELVAPSRCSSSVRLFCFHISPLDPPSAYPTCFPLTQFTCANGRCININWRCDNDNDC 1032
Query: 11710 SDGLDESQCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRT----- 11874
D DE+ C+ C +C+ G CI E+ CD DC + +DE H ++ T
Sbjct: 1033 GDNSDEAGCS-HSCSSVQFKCNSGRCIPEYWTCDGDNDCGDYSDETHANCTNQATRPPGG 1091
Query: 11875 CSPFEFECA-NSVCIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNI 12051
C EF+C +S+CIP ++ SDE + E + CDP ++F C S C++
Sbjct: 1092 CHVDEFQCRMDSLCIPMRWRCDGDTDCMDLSDERNCEGVTHMCDPAVKFSCKDSARCISK 1151
Query: 12052 LQLCNGFNDCGPNDFSDEHLSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDA 12231
+C+G +DC N D ++ S + ++D C+ CD DDC D
Sbjct: 1152 AWVCDGDSDCEDNSDEDNCDALVCKLSHHTCATNDSI------CLPAEKLCDGTDDCPDG 1205
Query: 12232 SDEIGCSKHGGKTSCEAFGNNGGCKHICTDV-RDGFYCHCRDGFRPDPQSPKECIDIDEC 12408
SDE C C +NGGC H CT + +GF C C G + K C C
Sbjct: 1206 SDEKLCD------LCAL--DNGGCSHNCTIIPGEGFMCSCPLGMELGADN-KTCQIQSFC 1256
Query: 12409 AGNNTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGAD-DSLVQL 12585
A + C+Q C K S C C+E +E + S C++ +I ++ + ++
Sbjct: 1257 AKHLKCSQKCEQEKSSVKCSCYEGWELEADMES-----CKSTDPFKPFIIFSNRHEIRRI 1311
Query: 12586 SLHGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERTIYRSAIANGNQSHEGQK 12765
LH + + +YW D E IYR ++ N + +
Sbjct: 1312 DLH-----KGEFSVLVPGLRNTIALDFHLSESTLYWTDVVEDKIYRGKLSE-NGALTSFE 1365
Query: 12766 LDVDFAAMGVVPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVC 12945
+ + + P +AVD+ GN++ V N++ I V
Sbjct: 1366 VVIQYGL--ATPEGLAVDWIAGNIY--WVESNLDQ---------------------IEVA 1400
Query: 12946 LPDGRYLKKIVAGHLQQPTALITAPSAGRICYS--DAGLHAKIECADMDGTHRQIIVKDL 13119
DG ++AG ++ P A+ P G + ++ DA L +IE A M G R+ I ++
Sbjct: 1401 KLDGTMRTTLLAGEVEHPRAIALDPRDGILFWTDWDASL-PRIEAASMSGEGRRTIHRET 1459
Query: 13120 VFS--PTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHI---PYAVDVFEN 13284
P + +D + RI W+D + + + DGS V+ P+AV ++
Sbjct: 1460 GSGGWPNGLTVDYME-RRIVWIDARSDAIYSAMYDGSGLIEVLRGHEYLSHPFAVTMYGG 1518
Query: 13285 HIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSH 13464
+YW + TL +K+ V+V+ ++V + + + C + CSH
Sbjct: 1519 EVYWTDWRTNTLAKANKWTGHNVTVVQRTNTQPFDLQV--YHPSRQPKAPNPCASSPCSH 1576
Query: 13465 LCVSLPSTGFACLCP 13509
LC+ + F+C CP
Sbjct: 1577 LCLINFNQTFSCACP 1591
Score = 220 bits (560), Expect = 9e-55
Identities = 147/517 (28%), Positives = 244/517 (46%), Gaps = 21/517 (4%)
Frame = +1
Query: 9385 SDEHANCTYSSCQPDFFQCANH-KCVPNSWKCDGNDDCEDGSDEKDCPKNSASAQKASKC 9561
+D+H +C F C + C+ W+CDG DC DGSDE + S K ++C
Sbjct: 1 ADDHPK----TCSSKQFVCKDQVTCISKGWRCDGEKDCPDGSDESP---DICSHSKVNQC 53
Query: 9562 SNGQFQCTSGE-CIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCMDMKIGY 9738
+ C E CI +++CD DCTD DE C ++ C+ C G
Sbjct: 54 PVNEHGCLDPEVCIPMSRLCDGVPDCTDGWDEGPHCR-EQAPACIAQRCQFNCSVTHDGP 112
Query: 9739 KCDCFEGFAIDISDQKSCHNVNECYEGISG-CSQKCDDKIGSYKCGCVDGYQLSSDDHSC 9915
+C C G+ + +D ++C + NEC + G CSQ C + GSY C CV+GY L D+ SC
Sbjct: 113 RCYCSAGYEVT-ADGRTCKDFNEC--NVYGTCSQTCSNTEGSYTCSCVEGYLLQPDNRSC 169
Query: 9916 KRTE--MEPEPFFLLANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLIDQGK 10089
K ++ P L+AN H IR ++ G L A +++D ++ ID G+
Sbjct: 170 KAKNDPVDRLPMLLIANLHDIRCTTLSGALSRLHAITTKQTMAMDFIYADETVCWIDVGE 229
Query: 10090 L----RLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCEL 10257
L + ++ + + + +++ E +A+DW+ + Y ++ + + VC
Sbjct: 230 TPAATHLKCASIPDLKTVTNIRTINITLSLHHVEQMAIDWLTKNFYFVDDVDDRVFVCNK 289
Query: 10258 DGRFCKTLIRDRIQQPKAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEH 10437
DG+ C TL+ + PK I + P G +FFT++ P + R +DG KL +
Sbjct: 290 DGQTCVTLLDQDLYNPKGIALDPAMGKVFFTDYGSTPRVERCDMDGQNRT-----KLVDT 344
Query: 10438 DLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRH-IPAQRTSHVSSMVVFDDYLY 10614
+ +P+ I +D + ++W DA+L+ I +D++G R I H+ + VF++YLY
Sbjct: 345 KIVFPHGITLDLVNRLVYWADAYLDYIEVVDYEGKNRHTIIQGLLIEHLYGLTVFENYLY 404
Query: 10615 WA---DWNLR---EVLRCDKWTGKNETILKKTVQLPNDLRIVHPMRQP-AYPNPCGDNN- 10770
+ NL V+R +++ + ++ + V L + H RQP + C +
Sbjct: 405 ATNSDEGNLNPKTSVIRVNRFNSSDFQVVTR-VDRGAALHVYHQRRQPQVRSHACTTDQF 463
Query: 10771 ---GGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTCE 10872
GGCS +CL+ TC C F L SD K+C+
Sbjct: 464 GKAGGCSDICLLSNSHKTRTCRCRSGFSLGSDGKSCK 500
Score = 189 bits (481), Expect = 1e-45
Identities = 216/1017 (21%), Positives = 410/1017 (40%), Gaps = 29/1017 (2%)
Frame = +1
Query: 5266 CSHLCLLNNKNTFTCKCPMGEKLDASGKKC--IDDAKPFLVIIQKTNVFGIEMNSASEKE 5439
CS C K++ C C G +L+A + C D KPF++ + + I+++
Sbjct: 1262 CSQKCE-QEKSSVKCSCYEGWELEADMESCKSTDPFKPFIIFSNRHEIRRIDLHKGE--- 1317
Query: 5440 TPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNGGNKT 5619
+ +VP GL N + ++ + +++ + A+ V
Sbjct: 1318 ---FSVLVP--GLRNTIALDFHLSESTLYWTDVVEDKIYRGKLSENGALTSFEV-----V 1367
Query: 5620 KMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVILSNDQSXXXXXXX 5799
+ A P+ L DW N+ IE+ + G R+ +L+ +
Sbjct: 1368 IQYGLATPEG---LAVDWIAGNIYWVESNLDQIEVAKLDGTM-RTTLLAGEVEHPRAIAL 1423
Query: 5800 XXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAIDTTNTRVY 5979
G +FW D + A +G + + + + +D R+
Sbjct: 1424 DPRD-----GILFWTDWDASLPRIEAASMSGEGRRTIHRETGSGGWPNGLTVDYMERRIV 1478
Query: 5980 FSEAKAGRISSVTYDGQDRHYVLSDGG--RQPNGLAFYGDRLFYADSAFDSIEVATINGD 6153
+ +A++ I S YDG VL P + YG +++ D +++ A
Sbjct: 1479 WIDARSDAIYSAMYDGSGLIEVLRGHEYLSHPFAVTMYGGEVYWTDWRTNTLAKAN---- 1534
Query: 6154 SQPPQWTHFKKDVENLANIKALQ------PRASSSGHPCHINNGNCDHICIPLMFAQRTC 6315
+WT V N + R + +PC + C H+C L+ +T
Sbjct: 1535 ----KWTGHNVTVVQRTNTQPFDLQVYHPSRQPKAPNPCA--SSPCSHLC--LINFNQTF 1586
Query: 6316 TCANGYVKDGQTSCKLFDES--FVIVATKTKVIGYPIDETQSKGVAMEPIGGL-SITGVD 6486
+CA ++ Q + ES F++ A + ++ G ID + + + ++T VD
Sbjct: 1587 SCACPHLMKLQPDKRTCKESRKFLLYARQIEIRGVDIDNPYYNYIISFTVPDIDNVTAVD 1646
Query: 6487 YDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINYNMYFINH 6666
YD IY ++ + I I + V+ + + LA+DW++ N+++ ++
Sbjct: 1647 YDAVEHRIYWSDVR--TQTIKRAFINGTGVETVVSADLPNA--HGLAVDWVSRNLFWTSY 1702
Query: 6667 DAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQRSFLDGSR 6846
DA + I V++LDG+++ ++ + P + + P+ LYW D I + +DGS
Sbjct: 1703 DANKKQINVARLDGSFKNAVIQG-LDKPHCLVLHPILGKLYWTDGDN---ISMANMDGSN 1758
Query: 6847 REVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPEL---VRSDIASAAGV 7017
+ + G P L +D +YW + I R + G E+ V+ ++ A +
Sbjct: 1759 HTTLFT-GQKGPVGLSIDYEKDQLYWISSGNGTISRCQLDGTKLEIMEGVKGKLSKATAL 1817
Query: 7018 ALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRASSP 7197
A+ G ++W D +++ K ++ T + + ++ + Q +
Sbjct: 1818 AIMGDKLWWADQGSDQIGTCDKKDGGNWKVMRNNT-----SPMMHMRIYDESAQKSGINL 1872
Query: 7198 CQITDNLRKSPCTQLCFATPGTQTPTCSCARGV-LKG--RTCEEPDTYIMFSDGDKIIDV 7368
C + C+QLC T T T C C G LK ++CE ++++FS + I +
Sbjct: 1873 CSNNNG----DCSQLCLPTSPT-TRACMCTAGYSLKSGQQSCEGMGSFLLFSVHEGIRGI 1927
Query: 7369 AIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAENPRLV 7548
++P K+ + P S D +Y+V ++ +++ A+ +
Sbjct: 1928 PLDPADKSDALV--PVSGTSLAVGIDFHAENDTIYWV-------DMGLSTISRAKRDQTW 1978
Query: 7549 FGASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTIASG--DWTYA 7722
+ I + + +DW+ IY+T + G + S D A
Sbjct: 1979 ---REDVVTNGIGRVEGITVDWIAGNIYWTDQGFDVIEVARLNGSFRYVVISQGLDKPRA 2035
Query: 7723 LAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVDFRNQK 7902
+ + P G LFW++ G PRIERS L G R V+V+ SIS P I++D+
Sbjct: 2036 ITVHPSKGYLFWTEWGQY-------PRIERSRLDGSQRLVLVNVSISWPNGISIDYEEGL 2088
Query: 7903 IYWAD-----VNRLNIEVADYDGQNRKVIASGYRAK--SLDIWDRWLYMSDPL-SNGVFR 8058
+YW D + R+N+E G+NR+++ + ++ +++ +Y SD +NG
Sbjct: 2089 LYWCDARTDKIERINLET----GENRELVLANNNMDMFAVSVFEEHIYWSDRTHANG--S 2142
Query: 8059 IDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLC 8229
I + S + V R G D++ N+ T+ +C+ +NGGC+QLC
Sbjct: 2143 IKRGSKDNATDAVQLRTGIG-----VQLKDIKVFNKARQQGTN-VCRNNNGGCEQLC 2193
Score = 164 bits (415), Expect = 6e-38
Identities = 167/689 (24%), Positives = 293/689 (42%), Gaps = 26/689 (3%)
Frame = +1
Query: 6313 CTCANGY-VKDGQTSCKLFD--ESFVIVATKTKVIGYPIDETQSKGVAMEPIGGLSIT-G 6480
C+C G+ ++ SCK D + F+I + + ++ + KG + GL T
Sbjct: 1275 CSCYEGWELEADMESCKSTDPFKPFIIFSNRHEIRRIDLH----KGEFSVLVPGLRNTIA 1330
Query: 6481 VDYDYESKTIYVAEA--SGINKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINYNMY 6654
+D+ T+Y + I +G + +S VI+ G T + LA+DWI N+Y
Sbjct: 1331 LDFHLSESTLYWTDVVEDKIYRGKLSENGALTSFEVVIQ--YGLATPEGLAVDWIAGNIY 1388
Query: 6655 FINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWAD-QGQKPTIQRSF 6831
++ + ++ IEV+KLDGT R LL + E P +IA+DP L+W D P I+ +
Sbjct: 1389 WVESNLDQ--IEVAKLDGTMRTTLLAGEVEHPRAIALDPRDGILFWTDWDASLPRIEAAS 1446
Query: 6832 LDGSRREVI---VSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTG-GTPELVRSD- 6996
+ G R I SG P L VD + I W DA+ D IY G G E++R
Sbjct: 1447 MSGEGRRTIHRETGSG-GWPNGLTVDYMERRIVWIDARSDAIYSAMYDGSGLIEVLRGHE 1505
Query: 6997 -IASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSN 7173
++ V ++G +YWTD R L +A ++ T D+ V+ +
Sbjct: 1506 YLSHPFAVTMYGGEVYWTDWRTNTLAKANKWTGHNVTVVQRTNTQPF-----DLQVYHPS 1560
Query: 7174 NQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCARGVLK----GRTCEEPDTYIMF 7341
QP+A +PC SPC+ LC QT +C+C ++K RTC+E ++++
Sbjct: 1561 RQPKAPNPCA------SSPCSHLCLIN-FNQTFSCACPH-LMKLQPDKRTCKESRKFLLY 1612
Query: 7342 SDGDKIIDVAIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSM 7521
+ +I V I+ + + + P+I N+ D D R+Y+ S V +
Sbjct: 1613 ARQIEIRGVDID-NPYYNYIISFTVPDIDNVTAVDYDAVEHRIYW---SDVRTQTIKRAF 1668
Query: 7522 NNAENPRLVFGASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGK----VMAIDTAGEHL 7689
N V A ++ + + +DW+++ +++T+ K V +D G
Sbjct: 1669 INGTGVETVVSA-------DLPNAHGLAVDWVSRNLFWTSYDANKKQINVARLD--GSFK 1719
Query: 7690 STIASG-DWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISL 7866
+ + G D + L + P G L+W+D I +N+ G + + +
Sbjct: 1720 NAVIQGLDKPHCLVLHPILGKLYWTDGD----------NISMANMDGSNHTTLFTGQKG- 1768
Query: 7867 PAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGY----RAKSLDIWDRWLYMSD 8034
P +++D+ ++YW I DG +++ +A +L I L+ +D
Sbjct: 1769 PVGLSIDYEKDQLYWISSGNGTISRCQLDGTKLEIMEGVKGKLSKATALAIMGDKLWWAD 1828
Query: 8035 PLSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGG 8214
S+ + DK+ G + + ++ +R++ + N LC +NG
Sbjct: 1829 QGSDQIGTCDKKDGGNWKVMRNNTSPMMHMRIYDESAQKSGIN---------LCSNNNGD 1879
Query: 8215 CDQLCTVVADDIGLAASKVQCSCNDTYEL 8301
C QLC + + + C C Y L
Sbjct: 1880 CSQLC------LPTSPTTRACMCTAGYSL 1902
Score = 158 bits (399), Expect = 4e-36
Identities = 119/377 (31%), Positives = 177/377 (46%), Gaps = 10/377 (2%)
Frame = +1
Query: 9769 DISDQKSCHNVNECYEGISGCSQKCDDKIGSYK-CGCVDGYQLSSDDHSCKRTEMEPEPF 9945
D S QKS +N C CSQ C + + C C GY L S SC E
Sbjct: 1862 DESAQKS--GINLCSNNNGDCSQLCLPTSPTTRACMCTAGYSLKSGQQSC-----EGMGS 1914
Query: 9946 FLLANKHY-IRKISID-GNKYE--LAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDL 10113
FLL + H IR I +D +K + + G V +D Y +D G + R
Sbjct: 1915 FLLFSVHEGIRGIPLDPADKSDALVPVSGTSLAVGIDFHAENDTIYWVDMGLSTISRAKR 1974
Query: 10114 DEMDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDR 10293
D+ + E V+ + + EGI VDW+ +Y ++ I V L+G F +I
Sbjct: 1975 DQ-----TWREDVVTNGIGRVEGITVDWIAGNIYWTDQGFDVIEVARLNGSFRYVVISQG 2029
Query: 10294 IQQPKAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDY 10473
+ +P+AI VHP KGYLF+TEW P I R LDGS L L + WPN I+IDY
Sbjct: 2030 LDKPRAITVHPSKGYLFWTEWGQYPRIERSRLDGSQRL-----VLVNVSISWPNGISIDY 2084
Query: 10474 FSDRLFWGDAHLNEIGFMDFD-GNGRRHIPAQRTSHVSSMVVFDDYLYWAD-WNLREVLR 10647
L+W DA ++I ++ + G R + A + ++ VF++++YW+D + ++
Sbjct: 2085 EEGLLYWCDARTDKIERINLETGENRELVLANNNMDMFAVSVFEEHIYWSDRTHANGSIK 2144
Query: 10648 CDKWTGKNETILKKT---VQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGY 10818
+ + +T VQL D+++ + RQ N C +NNGGC LCL G
Sbjct: 2145 RGSKDNATDAVQLRTGIGVQL-KDIKVFNKARQQG-TNVCRNNNGGCEQLCLYRGNGE-R 2201
Query: 10819 TCSCPDQFVLLSDQKTC 10869
TC+C +L D ++C
Sbjct: 2202 TCACA-HGMLAEDNRSC 2217
Score = 125 bits (314), Expect = 3e-26
Identities = 100/359 (27%), Positives = 154/359 (42%), Gaps = 9/359 (2%)
Frame = +1
Query: 9823 SGCSQKCDDKIG-SYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNK 9999
S CS C ++ C C +L D +CK E F L A + IR + ID
Sbjct: 1572 SPCSHLCLINFNQTFSCACPHLMKLQPDKRTCK----ESRKFLLYARQIEIRGVDIDNPY 1627
Query: 10000 YE----LAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNV 10167
Y DNV ++D D E + Y D + R ++ + ETV+ ++
Sbjct: 1628 YNYIISFTVPDIDNVTAVDYDAVEHRIYWSDVRTQTIKRAFING-----TGVETVVSADL 1682
Query: 10168 YGTEGIAVDWVGRKLYMLN--RQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYL 10341
G+AVDWV R L+ + ++ I V LDG F +I+ + +P +V+HP G L
Sbjct: 1683 PNAHGLAVDWVSRNLFWTSYDANKKQINVARLDGSFKNAVIQG-LDKPHCLVLHPILGKL 1741
Query: 10342 FFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIG 10521
++T+ I +DGS L G P ++IDY D+L+W + I
Sbjct: 1742 YWTDGD---NISMANMDGSNHTT-----LFTGQKG-PVGLSIDYEKDQLYWISSGNGTIS 1792
Query: 10522 FMDFDGNGRRHIPAQR--TSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTV 10695
DG + + S +++ + D L+WAD ++ CDK G N +++
Sbjct: 1793 RCQLDGTKLEIMEGVKGKLSKATALAIMGDKLWWADQGSDQIGTCDKKDGGNWKVMRNNT 1852
Query: 10696 QLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTCE 10872
+RI Q + N C +NNG CS LCL C C + L S Q++CE
Sbjct: 1853 SPMMHMRIYDESAQKSGINLCSNNNGDCSQLCL-PTSPTTRACMCTAGYSLKSGQQSCE 1910
Score = 120 bits (301), Expect = 1e-24
Identities = 109/455 (23%), Positives = 186/455 (39%), Gaps = 11/455 (2%)
Frame = +1
Query: 11962 SDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSFSEYG 12141
+D+ C S Q F C C++ C+G DC D SDE +CS S+
Sbjct: 1 ADDHPKTCSSKQ------FVCKDQVTCISKGWRCDGEKDCP--DGSDESPDICSH-SKVN 51
Query: 12142 DCSSDQFKCANGK-CVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKHICT 12318
C ++ C + + C+ + CD DC D DE G +C A C+ C+
Sbjct: 52 QCPVNEHGCLDPEVCIPMSRLCDGVPDCTDGWDE-GPHCREQAPACIA----QRCQFNCS 106
Query: 12319 DVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGSYLCRCHEDYENNVV 12498
DG C+C G+ + C D +EC TC+Q C NT+GSY C C E Y
Sbjct: 107 VTHDGPRCYCSAGYEVTADG-RTCKDFNECNVYGTCSQTCSNTEGSYTCSCVEGY----- 160
Query: 12499 VGSMTGKDCRAKGDAAN----VMIGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXXX 12666
+ + C+AK D + ++I + +L G+ + H
Sbjct: 161 LLQPDNRSCKAKNDPVDRLPMLLIANLHDIRCTTLSGALSRLHAITTKQTMAMDFIYA-- 218
Query: 12667 XPRKELMYWIDGSERT----IYRSAIANGNQSHEGQKLDVDFAAMGVVPTAIAVDYTTGN 12834
E + WID E + ++I + + +++ + V +A+D+ T N
Sbjct: 219 ---DETVCWIDVGETPAATHLKCASIPDLKTVTNIRTINITLSLHHV--EQMAIDWLTKN 273
Query: 12835 LFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALIT 13014
+ + +D++ +FVC DG+ ++ L P +
Sbjct: 274 FYFV-------------------DDVDDR----VFVCNKDGQTCVTLLDQDLYNPKGIAL 310
Query: 13015 APSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYR 13194
P+ G++ ++D G ++E DMDG +R +V + P + +D +YW D
Sbjct: 311 DPAMGKVFFTDYGSTPRVERCDMDGQNRTKLVDTKIVFPHGITLDL-VNRLVYWADAYLD 369
Query: 13195 RVDAVNIDGSERTTVVHDRHIP--YAVDVFENHIY 13293
++ V+ +G R T++ I Y + VFEN++Y
Sbjct: 370 YIEVVDYEGKNRHTIIQGLLIEHLYGLTVFENYLY 404
Score = 118 bits (296), Expect = 4e-24
Identities = 81/241 (33%), Positives = 105/241 (42%), Gaps = 30/241 (12%)
Frame = +1
Query: 430 FMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCD 609
F C + R C KCDG DC D SDE HT C +F+C + +CI W+CD
Sbjct: 862 FACKNNR-CIQERWKCDGDNDCLDNSDEAPELCHQHT-CPADRFKCQNN-RCIPLRWLCD 918
Query: 610 GSKDCADGSDEPDT-CEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDE-DECGEY- 780
G DC + DE +T C + C N++ C + RC P + CD DDCGD SDE D CGE
Sbjct: 919 GDNDCGNDEDESNTTCSARTCPPNQYPCASGRCIPISWTCDLDDDCGDRSDEPDSCGELV 978
Query: 781 ---RC---------------PPG---------KWNCPGTGHCIDQLKLCDGSKDCADGAD 879
RC PP ++ C G CI+ CD DC D +D
Sbjct: 979 APSRCSSSVRLFCFHISPLDPPSAYPTCFPLTQFTC-ANGRCININWRCDNDNDCGDNSD 1037
Query: 880 EQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCA 1059
E AGC S + C SG + + + TC N+C + Y D+ A
Sbjct: 1038 E--------------AGCSHSCSSVQFKCNSGRCIPE--YWTCDGDNDCGD--YSDETHA 1079
Query: 1060 N 1062
N
Sbjct: 1080 N 1080
Score = 117 bits (292), Expect = 1e-23
Identities = 113/457 (24%), Positives = 193/457 (41%), Gaps = 22/457 (4%)
Frame = +1
Query: 1051 LCANHRPGFTCSCLGDCFTLQMEHGPG-KDNLTMRGYCVSNNADKMK-----LFVARREG 1212
LC+N+ GDC L + P + + GY + + + L + EG
Sbjct: 1872 LCSNNN--------GDCSQLCLPTSPTTRACMCTAGYSLKSGQQSCEGMGSFLLFSVHEG 1923
Query: 1213 L--YRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQI 1386
+ L+P + + + ++ GIDF + I+W D + A D
Sbjct: 1924 IRGIPLDPADKSDALVPVSGTSLAVGIDFHAENDTIYWVDMGLSTISRAKRDQTWR---- 1979
Query: 1387 KKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALD 1566
+ + + + VDWI +Y + G I+V+ +G R V+++ GL P I +
Sbjct: 1980 EDVVTNGIGRVEGITVDWIAGNIYWTDQGFDVIEVARLNGSFRYVVISQGLDKPRAITVH 2039
Query: 1567 PLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRL 1737
P +G +F+T ++E + +DG+ R LVN +GI +D +YW D + D++
Sbjct: 2040 PSKGYLFWTEWGQYPRIERSRLDGSQRLVLVNVSISWPNGISIDYEEGLLYWCDARTDKI 2099
Query: 1738 ESIDYQ-GNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRL-GVIQVEKFGSDTKLLWS 1911
E I+ + G +R +V N+ F +++F++++YW+D T G I+ + T +
Sbjct: 2100 ERINLETGENRELVLANNNM--DMFAVSVFEEHIYWSDRTHANGSIKRGSKDNATDAVQL 2157
Query: 1912 NTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPC--TNADCEGMCILSKDNGGFGVGY 2085
T V I ++ Q G N C N CE +C L + NG
Sbjct: 2158 RTGIGVQLKDIKVFNKARQQGT-----------NVCRNNNGGCEQLC-LYRGNGE----R 2201
Query: 2086 KCACPIGQKLVNGKRCIDSIDYLLFSSNKIVRGIFPEINEKALAEAVLPISPISQ-RRIG 2262
CAC G + + C D YLL+S I++ I ++++ A PI P +
Sbjct: 2202 TCACAHGMLAEDNRSCRDYDGYLLYSERTILKSI--HLSDETNLNA--PIKPFEDPDHMK 2257
Query: 2263 MYFEVECDVHG------NSFFYADIMDNTIYRIRPDG 2355
+ D HG N F++DI I +I DG
Sbjct: 2258 NVIALSFDYHGGGGKGSNRIFFSDIHFGNIQQINDDG 2294
Score = 97.8 bits (242), Expect = 7e-18
Identities = 91/357 (25%), Positives = 151/357 (41%), Gaps = 24/357 (6%)
Frame = +1
Query: 7231 CTQLCFATPGTQTPTCSCARGVL---KGRTCEEPDTYIMFSDGDKIIDVAIEPDVKASR- 7398
C+Q C T G+ T CSC G L R+C+ + + D ++ +A D++ +
Sbjct: 141 CSQTCSNTEGSYT--CSCVEGYLLQPDNRSCKAKNDPV---DRLPMLLIANLHDIRCTTL 195
Query: 7399 -PLKDPFPEISNLQTFDVDVNLRRVYF--------VVESPVGVNISWFSMNNAENPRLVF 7551
I+ QT +D +Y V E+P ++ S+ + + V
Sbjct: 196 SGALSRLHAITTKQTMAMDF----IYADETVCWIDVGETPAATHLKCASIPDLKT---VT 248
Query: 7552 GASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTIASGDW--TYAL 7725
+ H+ M +DWLT+ YF +V + G+ T+ D +
Sbjct: 249 NIRTINITLSLHHVEQMAIDWLTKNFYFVDDVDDRVFVCNKDGQTCVTLLDQDLYNPKGI 308
Query: 7726 AIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVDFRNQKI 7905
A+DP G +F++D G PR+ER ++ G +R +V I P I +D N+ +
Sbjct: 309 ALDPAMGKVFFTDYG-------STPRVERCDMDGQNRTKLVDTKIVFPHGITLDLVNRLV 361
Query: 7906 YWADVNRLNIEVADYDGQNRKVIASGYRAK---SLDIWDRWLYMSDP------LSNGVFR 8058
YWAD IEV DY+G+NR I G + L +++ +LY ++ V R
Sbjct: 362 YWADAYLDYIEVVDYEGKNRHTIIQGLLIEHLYGLTVFENYLYATNSDEGNLNPKTSVIR 421
Query: 8059 IDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLC 8229
+++ + S + V R AL V+ + R+ C T Q K GGC +C
Sbjct: 422 VNRFNSSDFQVVTRVDR-GAALHVYHQRRQPQVRSHACT--TDQFGKA--GGCSDIC 473
Score = 89.0 bits (219), Expect = 3e-15
Identities = 69/220 (31%), Positives = 99/220 (44%), Gaps = 2/220 (0%)
Frame = +1
Query: 11587 NSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQC--SDGLDESQCTLRRCLPG 11760
++ + S TRP E + IPGS G+ C ++G S C +P
Sbjct: 772 DAHQQQGSSASHTRPFRTGENMSDS--FIPGSPFGLGSNACRVNNGGCSSLCL---AIPD 826
Query: 11761 HRQCDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFECANSVCIPRKFMXXX 11940
R C D+ D N + + V+ C P EF C N+ CI ++
Sbjct: 827 GRSCGCAD--------DQILDGDNVTCKANPSYVNPPQCQPGEFACKNNRCIQERWKCDG 878
Query: 11941 XXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMC 12120
SDE C C P RF+C ++R C+ + LC+G NDCG ND DE + C
Sbjct: 879 DNDCLDNSDEAPELCHQHTC-PADRFKCQNNR-CIPLRWLCDGDNDCG-ND-EDESNTTC 934
Query: 12121 SSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDE 12240
S+ + C +Q+ CA+G+C+ + CD DDCGD SDE
Sbjct: 935 SART----CPPNQYPCASGRCIPISWTCDLDDDCGDRSDE 970
Score = 83.2 bits (204), Expect = 2e-13
Identities = 86/390 (22%), Positives = 162/390 (41%), Gaps = 8/390 (2%)
Frame = +1
Query: 12397 IDECAGNN-TCTQLCLNTKGSY-LCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADD 12570
I+ C+ NN C+QLCL T + C C Y S+ +G + ++ +
Sbjct: 1870 INLCSNNNGDCSQLCLPTSPTTRACMCTAGY-------SLKSGQQSCEGMGSFLLFSVHE 1922
Query: 12571 SLVQLSLHGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERTIYRSAIANGNQS 12750
+ + L + ++ + +YW+D TI R+ +
Sbjct: 1923 GIRGIPLDPA--DKSDALVPVSGTSLAVGIDFHAENDTIYWVDMGLSTISRA------KR 1974
Query: 12751 HEGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTG 12930
+ + DV +G V I VD+ GN++ +Q
Sbjct: 1975 DQTWREDVVTNGIGRVE-GITVDWIAGNIYWT-----------------------DQGFD 2010
Query: 12931 FIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIV 13110
I V +G + +++ L +P A+ PS G + +++ G + +IE + +DG+ R ++V
Sbjct: 2011 VIEVARLNGSFRYVVISQGLDKPRAITVHPSKGYLFWTEWGQYPRIERSRLDGSQRLVLV 2070
Query: 13111 KDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNID-GSERTTVVHDRHIP-YAVDVFEN 13284
+ P ++ID +G +YW D + +++ +N++ G R V+ + ++ +AV VFE
Sbjct: 2071 NVSISWPNGISIDYEEG-LLYWCDARTDKIERINLETGENRELVLANNNMDMFAVSVFEE 2129
Query: 13285 HIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRVS--QKYAKDTQRTVSGC--ERA 13452
HIYW R + K G + A L G V++ + + K Q+ + C
Sbjct: 2130 HIYWSDRTHANGSI--KRGSKDNATDAVQLRTGIGVQLKDIKVFNKARQQGTNVCRNNNG 2187
Query: 13453 QCSHLCVSLPSTGFACLCPDGIVPQLDGSC 13542
C LC+ + C C G++ + + SC
Sbjct: 2188 GCEQLCLYRGNGERTCACAHGMLAEDNRSC 2217
Score = 77.8 bits (190), Expect = 7e-12
Identities = 115/473 (24%), Positives = 171/473 (35%), Gaps = 29/473 (6%)
Frame = +1
Query: 265 HPG-CKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDEKD--CPASTVDCSSQNVFM 435
HP C S Q+ C V+CI++ RCD DC DGSDE C S V+ N
Sbjct: 4 HPKTCSSKQFVCKD----QVTCISKGWRCDGEKDCPDGSDESPDICSHSKVNQCPVNEHG 59
Query: 436 CADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACF--QYQFRCA---DKTQCIQKSW 600
C D C +S+ CDG DC D DE C AC + QF C+ D +C
Sbjct: 60 CLDPEVCIPMSRLCDGVPDCTDGWDEGPHCREQAPACIAQRCQFNCSVTHDGPRCY---- 115
Query: 601 VCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEY 780
C+ G + TA+ CK+ C+ Y C E G Y
Sbjct: 116 -------CSAGYE---------VTADGRTCKDFN------ECNVYGTCSQTCSNTE-GSY 152
Query: 781 RCPPGKWNCPGTGHCIDQLKLCDGSKDC-ADGADEQQCSQNLCPSLGCQAGCHPSPHGGE 957
C C++ L ++ C A + L +L H
Sbjct: 153 TC-----------SCVEGYLLQPDNRSCKAKNDPVDRLPMLLIANL----------HDIR 191
Query: 958 CTCPSGYKLDDRFHRTCSDINECAEFGYCDQ----LCANHRPGFT---CSCLGDC----- 1101
CT SG R H + +F Y D+ + P T C+ + D
Sbjct: 192 CTTLSGAL--SRLHAITTKQTMAMDFIYADETVCWIDVGETPAATHLKCASIPDLKTVTN 249
Query: 1102 -----FTLQMEH--GPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKL 1260
TL + H D LT Y V + D ++FV ++G + + D K
Sbjct: 250 IRTINITLSLHHVEQMAIDWLTKNFYFVDDVDD--RVFVCNKDGQTCVTLLDQDLYNPK- 306
Query: 1261 ASGEFIYGIDFDYGDRKIFWTDRLAHSAFS-ADVDDEGEISQIKKLSLKSLVYPRCLAVD 1437
GI D K+F+TD + D+D + KL +V+P + +D
Sbjct: 307 -------GIALDPAMGKVFFTDYGSTPRVERCDMDGQNR----TKLVDTKIVFPHGITLD 355
Query: 1438 WITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTN 1596
+ +Y ++ I+V Y+G+ R ++ GL + L ++ TN
Sbjct: 356 LVNRLVYWADAYLDYIEVVDYEGKNRHTII-QGLLIEHLYGLTVFENYLYATN 407
Score = 75.1 bits (183), Expect = 5e-11
Identities = 44/136 (32%), Positives = 59/136 (43%), Gaps = 5/136 (3%)
Frame = +1
Query: 517 DSCSRNHTACFQYQFRCADKTQC-IQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCK 693
++C N+ C D C + DG D P +C EF CK
Sbjct: 808 NACRVNNGGCSSLCLAIPDGRSCGCADDQILDG--DNVTCKANPSYVNPPQCQPGEFACK 865
Query: 694 NKRCQPRKFRCDYYDDCGDNSDE--DECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCA 867
N RC +++CD +DC DNSDE + C ++ CP ++ C CI LCDG DC
Sbjct: 866 NNRCIQERWKCDGDNDCLDNSDEAPELCHQHTCPADRFKCQ-NNRCIPLRWLCDGDNDCG 924
Query: 868 DGADEQQ--CSQNLCP 909
+ DE CS CP
Sbjct: 925 NDEDESNTTCSARTCP 940
Score = 73.2 bits (178), Expect = 2e-10
Identities = 50/179 (27%), Positives = 79/179 (43%), Gaps = 8/179 (4%)
Frame = +1
Query: 9139 RTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEK-KECNKGEF 9315
+TC+ ++F C + + CI + W CDG+ C G DES ++C K +C E
Sbjct: 6 KTCSSKQFVC-------KDQVTCISKGWRCDGEKDCPDGSDESPDICSHSKVNQCPVNEH 58
Query: 9316 RCSN-QHCIHSTWECDGDNDCLDGSDEHANCTYSS----CQPDFFQCANHKCVPNSWKCD 9480
C + + CI + CDG DC DG DE +C + Q F C+ P +
Sbjct: 59 GCLDPEVCIPMSRLCDGVPDCTDGWDEGPHCREQAPACIAQRCQFNCSVTHDGPRCYCSA 118
Query: 9481 GNDDCEDGSDEKDCPKNSASAQKASKCSN--GQFQCTSGECIDDAKVCDRNFDCTDRSD 9651
G + DG KD + + + CSN G + C+ C++ + N C ++D
Sbjct: 119 GYEVTADGRTCKDFNECNVYGTCSQTCSNTEGSYTCS---CVEGYLLQPDNRSCKAKND 174
Score = 70.1 bits (170), Expect = 2e-09
Identities = 101/487 (20%), Positives = 178/487 (35%), Gaps = 50/487 (10%)
Frame = +1
Query: 12361 RPDPQSPKECIDIDECAGNNTCTQLCL--NTKGSYLCRCHEDYENNVVVGSMTGKDCRAK 12534
R PQ D+ C+ +CL N+ + CRC + +GS GK C+
Sbjct: 448 RRQPQVRSHACTTDQFGKAGGCSDICLLSNSHKTRTCRCRSGFS----LGS-DGKSCKKP 502
Query: 12535 GDAANVMIGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERT 12714
++ G + + + E +Y+ D +
Sbjct: 503 DHELFLVYGKGRPGIIRGMDMNAKVPDEYMIPIENLMNPRALDFHAASEYIYFADATSYI 562
Query: 12715 IYRSAIANGNQSHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAVSENIENGLVTARKK 12894
I G Q +G + D IAVD+ GNL+ + + + AR +
Sbjct: 563 I-------GRQKIDGTERDTILKEGIHTVEGIAVDWMGGNLYWT--DDGPKKTISVARLE 613
Query: 12895 RMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSD------AGL 13056
+ S+ K ++ G + P A++ P G + ++D
Sbjct: 614 KASQT------------------RKTLIEGKMSHPRAIVVDPQHGWMYWTDWEEDPSESN 655
Query: 13057 HAKIECADMDGTHRQI-IVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERT 13233
KI+ A MDG+H QI + V P +++D +G +YWVD Y R++ V ++ +ER
Sbjct: 656 RGKIKKAWMDGSHHQIFLTSKTVLWPNGLSLDIPQG-ILYWVDAYYDRIEMVYLNTTERK 714
Query: 13234 TVVHDRHIPYAVDV--FENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQK 13407
V + + +A + ++ ++W ++Y D+ + V++L ++ +RV
Sbjct: 715 VVYEGQELTHAFGLCHYKQFLFWNEYRGGSIYKLDQVTK-TVTLLRNERPPIFEIRVYDA 773
Query: 13408 Y------AKDTQRTVSG---------------------CERAQCSHLCVSLPSTGFACLC 13506
+ A T+ +G CS LC+++P G +C C
Sbjct: 774 HQQQGSSASHTRPFRTGENMSDSFIPGSPFGLGSNACRVNNGGCSSLCLAIPD-GRSCGC 832
Query: 13507 PDGIVPQLDGSCATQHVE-ALTMPKQCK-----CTNG------GKCRLDGSCECTSDFEG 13650
D + LDG T + P QC+ C N KC D C SD
Sbjct: 833 ADDQI--LDGDNVTCKANPSYVNPPQCQPGEFACKNNRCIQERWKCDGDNDCLDNSDEAP 890
Query: 13651 DQCEKES 13671
+ C + +
Sbjct: 891 ELCHQHT 897
Score = 63.9 bits (154), Expect = 1e-07
Identities = 44/139 (31%), Positives = 59/139 (41%), Gaps = 13/139 (9%)
Frame = +1
Query: 11512 EFRCATSGKCIPRRWMCDTENDCGDNSDELDASCG-GTTRPCSESEFRCNDGK-CIPGSK 11685
+F C CI + W CD E DC D SDE C C +E C D + CIP S+
Sbjct: 12 QFVCKDQVTCISKGWRCDGEKDCPDGSDESPDICSHSKVNQCPVNEHGCLDPEVCIPMSR 71
Query: 11686 VCDGTIQCSDGLDES--------QCTLRRCLPGHRQCDDGT---CIAEHKWCDRKKDCPN 11832
+CDG C+DG DE C +RC DG C A ++ + C +
Sbjct: 72 LCDGVPDCTDGWDEGPHCREQAPACIAQRCQFNCSVTHDGPRCYCSAGYEVTADGRTCKD 131
Query: 11833 AADELHCEDVSRRTCSPFE 11889
+E + +TCS E
Sbjct: 132 -FNECNVYGTCSQTCSNTE 149
Score = 60.8 bits (146), Expect = 9e-07
Identities = 92/446 (20%), Positives = 146/446 (32%), Gaps = 25/446 (5%)
Frame = +1
Query: 3556 TCAANQFSCANG-RCIPIYWLCDGDNDCYDGTDEDKERCPPV---QCSALQFRCANGRQC 3723
TC++ QF C + CI W CDG+ DC DG+DE + C QC + C + C
Sbjct: 7 TCSSKQFVCKDQVTCISKGWRCDGEKDCPDGSDESPDICSHSKVNQCPVNEHGCLDPEVC 66
Query: 3724 VPLRNHXXXXXXXXXXXXXXXXAVTAESCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSD 3903
+P+ CT + PA D
Sbjct: 67 IPM----------------SRLCDGVPDCTDGWDEGPHCREQAPACIAQRCQFNCSVTHD 110
Query: 3904 EPKFGCTSGRQCSSDQFKCGN-------GRCILNNWLCDGENDCGDGSD---ESSERGCK 4053
P+ C++G + ++D C + G C +G C + R CK
Sbjct: 111 GPRCYCSAGYEVTADGRTCKDFNECNVYGTCSQTCSNTEGSYTCSCVEGYLLQPDNRSCK 170
Query: 4054 TSMN-ARKCP------FEHVACENDQETCIPLHQLCDGKTHCPGGTDEGGRCARDLCSAD 4212
+ + P + C LH + +T A D AD
Sbjct: 171 AKNDPVDRLPMLLIANLHDIRCTTLSGALSRLHAITTKQT-----------MAMDFIYAD 219
Query: 4213 RAGCSFKCHNSPNGPICSCPFGEQLVNKTKCEPENECLDSSSCSQRCKDEKHGFTCSCDE 4392
C +P C L T N L Q
Sbjct: 220 ETVCWIDVGETPAATHLKCASIPDLKTVTNIRTINITLSLHHVEQMA------------- 266
Query: 4393 GYELDVDKRTCKVADNVKDTRIYVSNRNR---IYYSDHKLDNWHTFGAIVENAIALAWDS 4563
+D + D+V D R++V N++ + D L N IAL D
Sbjct: 267 ---IDWLTKNFYFVDDV-DDRVFVCNKDGQTCVTLLDQDLYN--------PKGIAL--DP 312
Query: 4564 LTDRIYWSDI-REKKILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVDSSLNTIE 4740
+++++D ++ + +G N T + + GI LD V R +YW D+ L+ IE
Sbjct: 313 AMGKVFFTDYGSTPRVERCDMDGQNRTKLVDTKIVFPHGITLDLVNRLVYWADAYLDYIE 372
Query: 4741 VANLEDPKQRTLLVHQNVSQPRGIAV 4818
V + E + T++ + G+ V
Sbjct: 373 VVDYEGKNRHTIIQGLLIEHLYGLTV 398
Score = 60.1 bits (144), Expect = 2e-06
Identities = 63/282 (22%), Positives = 116/282 (40%), Gaps = 5/282 (1%)
Frame = +1
Query: 12685 MYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTA--IAVDYTTGNLFIAAVSE 12858
+YW D +TI R+ I NG V+ +P A +AVD+ + NLF +
Sbjct: 1654 IYWSDVRTQTIKRAFI-NGT--------GVETVVSADLPNAHGLAVDWVSRNLFWTSYDA 1704
Query: 12859 NIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRIC 13038
N KK+++ V DG + ++ G L +P L+ P G++
Sbjct: 1705 N---------KKQIN------------VARLDGSFKNAVIQG-LDKPHCLVLHPILGKLY 1742
Query: 13039 YSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNID 13218
++D I A+MDG++ + P ++ID K +++YW+ + +D
Sbjct: 1743 WTDGD---NISMANMDGSNHTTLFTGQK-GPVGLSIDYEK-DQLYWISSGNGTISRCQLD 1797
Query: 13219 GSERTT---VVHDRHIPYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHT 13389
G++ V A+ + + ++W + S + DK G V+ ++
Sbjct: 1798 GTKLEIMEGVKGKLSKATALAIMGDKLWWADQGSDQIGTCDKKDGGNWKVMRNNTSPMMH 1857
Query: 13390 VRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTGFACLCPDG 13515
+R+ + A+ + + CS LC+ T AC+C G
Sbjct: 1858 MRIYDESAQKSGINLCSNNNGDCSQLCLPTSPTTRACMCTAG 1899
Score = 55.1 bits (131), Expect = 5e-05
Identities = 38/142 (26%), Positives = 58/142 (40%), Gaps = 27/142 (19%)
Frame = +1
Query: 8392 FQCGDG-SCILLGATCDSKPDCADASDENPNYCN---TRSCPEDYNLCTNRR-CIDSAKK 8556
F C D +CI G CD + DC D SDE+P+ C+ CP + + C + CI ++
Sbjct: 13 FVCKDQVTCISKGWRCDGEKDCPDGSDESPDICSHSKVNQCPVNEHGCLDPEVCIPMSRL 72
Query: 8557 CNHIDDCGDGSDE-----LDCPSAVA-----------------CAEGTFPCSNGHCINQT 8670
C+ + DC DG DE P+ +A C+ G ++G
Sbjct: 73 CDGVPDCTDGWDEGPHCREQAPACIAQRCQFNCSVTHDGPRCYCSAGYEVTADGRTCKDF 132
Query: 8671 KVCDGHNDCHDEQVSDESLATC 8736
C+ + C + E TC
Sbjct: 133 NECNVYGTCSQTCSNTEGSYTC 154
Score = 55.1 bits (131), Expect = 5e-05
Identities = 30/85 (35%), Positives = 38/85 (44%), Gaps = 8/85 (9%)
Frame = +1
Query: 8746 PIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGR--- 8916
P C + C + CI CDG DC D +DE+ C + + Q CP
Sbjct: 5 PKTCSSKQFVCKDQVTCISKGWRCDGEKDCPDGSDESPDICSHSKVNQ----CPVNEHGC 60
Query: 8917 -----CIPETWQCDGDNDCSDGWDE 8976
CIP + CDG DC+DGWDE
Sbjct: 61 LDPEVCIPMSRLCDGVPDCTDGWDE 85
Score = 54.3 bits (129), Expect = 9e-05
Identities = 34/113 (30%), Positives = 51/113 (45%), Gaps = 11/113 (9%)
Frame = +1
Query: 3418 DGQKPVCAAKKFQC-DNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNAT---CAANQFSCA 3585
D C++K+F C D CI + W+ E ++C ++ C N+ C
Sbjct: 2 DDHPKTCSSKQFVCKDQVTCISKGWRCDGEKDCPDGSDESPDICSHSKVNQCPVNEHGCL 61
Query: 3586 NGR-CIPIYWLCDGDNDCYDGTDED---KERCPPVQCSALQFRCA---NGRQC 3723
+ CIP+ LCDG DC DG DE +E+ P QF C+ +G +C
Sbjct: 62 DPEVCIPMSRLCDGVPDCTDGWDEGPHCREQAPACIAQRCQFNCSVTHDGPRC 114
Score = 53.1 bits (126), Expect = 2e-04
Identities = 25/54 (46%), Positives = 30/54 (55%), Gaps = 2/54 (3%)
Frame = +1
Query: 10879 CTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRI--CPVGEFQC 11034
C+ +QF C D CI K W CDGE DC DGSDE + ++ CPV E C
Sbjct: 8 CSSKQFVCK-DQVTCISKGWRCDGEKDCPDGSDESPDICSHSKVNQCPVNEHGC 60
Score = 52.4 bits (124), Expect = 3e-04
Identities = 40/117 (34%), Positives = 49/117 (41%), Gaps = 5/117 (4%)
Frame = +1
Query: 3139 AEKIEQLCSSNSTQFQCKNG-RCIPKEWKCDGENDCLDESDEIDEKGDKCFHE--TECAE 3309
A+ + CSS QF CK+ CI K W+CDGE DC D S DE D C H +C
Sbjct: 1 ADDHPKTCSSK--QFVCKDQVTCISKGWRCDGEKDCPDGS---DESPDICSHSKVNQCPV 55
Query: 3310 NTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDG--QKPVCAAKKFQCDNHRC 3474
N C + + CIP V C DG + P C + C RC
Sbjct: 56 NEHGCLDPEVCIP-----------MSRLCDGVPDCTDGWDEGPHCREQAPACIAQRC 101
Score = 48.9 bits (115), Expect = 0.004
Identities = 47/172 (27%), Positives = 65/172 (37%), Gaps = 26/172 (15%)
Frame = +1
Query: 8620 CAEGTFPCSNG-HCINQTKVCDGHNDCHDEQVSDES--------LATCPGLPIDCRGVKV 8772
C+ F C + CI++ CDG DC D SDES + CP C +V
Sbjct: 8 CSSKQFVCKDQVTCISKGWRCDGEKDCPDG--SDESPDICSHSKVNQCPVNEHGCLDPEV 65
Query: 8773 RCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQ---------------CAQHYVRCP 8907
P + +C D DG+D+ G E C+ Q+ C+ Y
Sbjct: 66 CIPMSRLCDGVPDCTDGWDE-GPHCREQAPACIAQRCQFNCSVTHDGPRCYCSAGYEVTA 124
Query: 8908 SGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKI--CVGDYLFQCDNLKC 9057
GR + +C+ CS C++T G CV YL Q DN C
Sbjct: 125 DGRTCKDFNECNVYGTCSQ-------TCSNTEGSYTCSCVEGYLLQPDNRSC 169
Score = 48.1 bits (113), Expect = 0.006
Identities = 44/175 (25%), Positives = 53/175 (30%), Gaps = 8/175 (4%)
Frame = +1
Query: 11398 CSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCD----DVGEFRCATSGKCIPRRWMCD 11565
C CI C+G+ DC D SDE C V E C CIP +CD
Sbjct: 15 CKDQVTCISKGWRCDGEKDCPDGSDESPDICSHSKVNQCPVNEHGCLDPEVCIPMSRLCD 74
Query: 11566 TENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTLR 11745
DC D DE C E C +C CS D +C
Sbjct: 75 GVPDCTDGWDE--------GPHCREQAPACIAQRC---------QFNCSVTHDGPRC--- 114
Query: 11746 RCLPGHRQCDDGTCIAEHKWCD----RKKDCPNAADELHCEDVSRRTCSPFEFEC 11898
C G+ DG + C+ + C N C V P C
Sbjct: 115 YCSAGYEVTADGRTCKDFNECNVYGTCSQTCSNTEGSYTCSCVEGYLLQPDNRSC 169
Score = 46.6 bits (109), Expect = 0.018
Identities = 43/165 (26%), Positives = 59/165 (35%), Gaps = 2/165 (1%)
Frame = +1
Query: 8845 ADENQLFCMNQQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVG 9024
AD++ C ++Q +V CI + W+CDG+ DC DG DE+ IC
Sbjct: 1 ADDHPKTCSSKQ----FVCKDQVTCISKGWRCDGEKDCPDGSDES---------PDICSH 47
Query: 9025 DYLFQCDNLKCISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYE 9204
+ QC + HG C D E
Sbjct: 48 SKVNQCP-----------------------VNEHG-----CLDPEV-------------- 65
Query: 9205 CIPRAWLCDGDVTCAGGEDESTELCKTEKKEC--NKGEFRCSNQH 9333
CIP + LCDG C G DE C+ + C + +F CS H
Sbjct: 66 CIPMSRLCDGVPDCTDGWDEGPH-CREQAPACIAQRCQFNCSVTH 109
Score = 44.7 bits (104), Expect = 0.068
Identities = 25/68 (36%), Positives = 34/68 (49%), Gaps = 1/68 (1%)
Frame = +1
Query: 10852 SDQKTCEPN-CTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEF 11028
SD+ C+ C C +D+ C+P CDG DC DGSD E +C +C +
Sbjct: 1165 SDEDNCDALVCKLSHHTCATNDSICLPAEKLCDGTDDCPDGSD---EKLCD--LCALDNG 1219
Query: 11029 QCTNHNCT 11052
C +HNCT
Sbjct: 1220 GC-SHNCT 1226
Score = 42.0 bits (97), Expect = 0.44
Identities = 25/91 (27%), Positives = 40/91 (43%), Gaps = 8/91 (8%)
Frame = +1
Query: 11251 RNCTAEEFRCNNN-KCIAKAWRXXXXXXXXXXXXETPE-CAQI---ECKKGWTRCSSSYR 11415
+ C++++F C + CI+K WR E+P+ C+ +C C
Sbjct: 6 KTCSSKQFVCKDQVTCISKGWRCDGEKDCPDGSDESPDICSHSKVNQCPVNEHGCLDPEV 65
Query: 11416 CIPNWAFCNGQDDCRDNSDED---KQRCPTC 11499
CIP C+G DC D DE +++ P C
Sbjct: 66 CIPMSRLCDGVPDCTDGWDEGPHCREQAPAC 96
Score = 38.1 bits (87), Expect = 6.3
Identities = 24/77 (31%), Positives = 31/77 (40%), Gaps = 13/77 (16%)
Frame = +1
Query: 13456 CSHLCVSLPSTGFACLCP-------DGIVPQLDGSCA-----TQHVEALTMPKQCKCTNG 13599
CSH C +P GF C CP D Q+ CA +Q E +C C G
Sbjct: 1221 CSHNCTIIPGEGFMCSCPLGMELGADNKTCQIQSFCAKHLKCSQKCEQEKSSVKCSCYEG 1280
Query: 13600 GKCRLD-GSCECTSDFE 13647
+ D SC+ T F+
Sbjct: 1281 WELEADMESCKSTDPFK 1297
>gi|17298317|gb|AAL38109.1| candidate tumor suppressor protein [Homo
sapiens]
Length = 1537
Score = 820 bits (2118), Expect = 0.0
Identities = 517/1612 (32%), Positives = 760/1612 (47%), Gaps = 57/1612 (3%)
Frame = +1
Query: 8878 QCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKC 9057
+C ++Y CPSGRCI TW CDG DC DG DE H + + + + F C KC
Sbjct: 5 KCEENYFSCPSGRCILNTWICDGQKDCEDGRDEFHCDSSCSWNQ--------FACSAQKC 56
Query: 9058 ISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGD 9237
IS+ +I S CG TC F C Q C+PR WLCDG+
Sbjct: 57 ISKHWICDGEDDCGDGLD-ESDSICGAITCAADMFSC-------QGSRACVPRHWLCDGE 108
Query: 9238 VTCAGGEDESTELCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSS 9417
C G DE + C++ F C N+ CI + CD D+DC DGSDE C Y
Sbjct: 109 RDCPDGSDELSTAGCAPNNTCDENAFMCHNKVCIPKQFVCDHDDDCGDGSDESPQCGYRQ 168
Query: 9418 CQPDFFQCANHKCVPNS-WKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTSGE 9594
C + F CA+ +C+ N+ W+CDG+ DC D SDE P N C++ F C +G
Sbjct: 169 CGTEEFSCADGRCLLNTQWQCDGDFDCPDHSDE--APLNPKCKSAXQSCNSSFFMCKNGR 226
Query: 9595 CIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDI 9774
CI +CD DC D SDE + C I+EC + C Q C D+ + YKC C+ GF +
Sbjct: 227 CIPSGGLCDNKDDCGDGSDERN-CHINECLSKKVSGCSQDCQDLPVSYKCKCWPGFQLK- 284
Query: 9775 SDQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLL 9954
D K+C +++EC G CSQ+C + G+YKC C DGY++ D+ + ++ + EPF +L
Sbjct: 285 DDGKTCVDIDECSSGFP-CSQQCINTYGTYKCLCTDGYEIQPDNPNGCKSLSDEEPFLIL 343
Query: 9955 ANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPL 10134
A+ H IRKIS DG+ Y L QG +NV+++D D E+ Y ID + R++ L
Sbjct: 344 ADHHEIRKISTDGSNYTLLKQGLNNVIAIDFDYREEFIYWIDSSRPNGSRIN----RMCL 399
Query: 10135 SSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAI 10314
+ + + HN +AVDW+G+ LY + ++R I V +L+G + L+ R++ P+ +
Sbjct: 400 NGSDIKVVHNTAVPNALAVDWIGKNLYWSDTEKRIIEVSKLNGLYPTILVSKRLKFPRDL 459
Query: 10315 VVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFW 10494
+ P GYL++ + P+IGR+ +DG+ + + E + P A+ IDY + RL+W
Sbjct: 460 SLDPQAGYLYWIDCCEYPHIGRVGMDGTNQ-----SVVIETKISRPMALTIDYVNRRLYW 514
Query: 10495 GDAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNE 10674
D N I F + DG+ R +P Q V ++ +F+DY+YW D + + R K +G +
Sbjct: 515 ADE--NHIEFSNMDGSHRHKVPNQDIPGVIALTLFEDYIYWTDGKTKSLSRAHKTSGADR 572
Query: 10675 TILKKTVQLPNDLRIVHPMRQP-AYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLL 10851
L + D+++ H RQP + C NNGGCSHLCL+ A G +TC+CP F L
Sbjct: 573 LSLIYSWHAITDIQVYHSYRQPDVSKHLCMINNGGCSHLCLL-APGKTHTCACPTNFYLA 631
Query: 10852 SDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQ 11031
+D +TC NCT QF C D KCIP W CD DC DGSDEP + C + C G FQ
Sbjct: 632 ADNRTCLSNCTASQFRCKTD--KCIPFWWKCDTVDDCGDGSDEPDD--CPEFRCQPGRFQ 687
Query: 11032 CTNHNCTRPFQIXXXXXXXXXXXXEQNCD-KACDPWMFKCAATGRCIPRRFTXXXXXXXX 11208
C C P I E NCD C FKC +CIP
Sbjct: 688 CGTGLCALPAFICDGENDCGDNSDELNCDTHVCLSGQFKCTKNQKCIPVNLRCNGQDDCG 747
Query: 11209 XRSDEADTLCMSAERNCTAEEFRCNNNK-CIAKAWRXXXXXXXXXXXXETPECAQIECKK 11385
DE D E +C+ + F+C K CI+K W E C + C
Sbjct: 748 DEEDERD----CPENSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEA-NCDKKTCGP 802
Query: 11386 GWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMCD 11565
+C ++ CIP+ C+ Q+DC DNSDE+ + TC + +F CA +G C+ R+ CD
Sbjct: 803 HEFQCKNN-NCIPDHWRCDSQNDCSDNSDEENCKPQTC-TLKDFLCA-NGDCVSSRFWCD 859
Query: 11566 TENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQ---- 11733
+ DC D SDE + CS+ +FRC++G+CIP CDG C G DE
Sbjct: 860 GDFDCADGSDERNCETS-----CSKDQFRCSNGQCIPAKWKCDGHEDCKYGEDEKSCEPA 914
Query: 11734 ----------CTLRRCLP------GHRQCDDGT----CIAEHK----------------W 11805
C C+ G C DG+ C+ E K W
Sbjct: 915 SPTCSSREYICASDGCISASLKCNGEYDCADGSDEMDCVTECKEDQFRCKNKAHCIPIRW 974
Query: 11806 -CDRKKDCPNAADELHCEDVSRRTCSPFEFECANSVCIPRKFMXXXXXXXXXXSDETSSE 11982
CD DC + +DE +CE C EF C NS+C ++ SDE
Sbjct: 975 LCDGIHDCVDGSDEENCER-GGNICRADEFLCNNSLCKLHFWVCDGEDDCGDNSDEAPDM 1033
Query: 11983 CRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSFSEY--GDCSSD 12156
C C RC ++R+CL Q+CNG ++CG N D C Y C D
Sbjct: 1034 CVKFLCPSTRPHRCRNNRICLQSEQMCNGIDECGDNSDEDH----CGGKLTYKARPCKKD 1089
Query: 12157 QFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKHICTDVRDGF 12336
+F C+N KC+ + CDR DDCGD SDE GC + +CE N G C ++
Sbjct: 1090 EFACSNKKCIPMDLQCDRLDDCGDGSDEQGCRIAPTEYTCEDNVNPCGDDAYCNQIKTSV 1149
Query: 12337 YCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTG 12516
+C C+ GF+ + ++ ++C D++EC TC+ C+N +GSY C C ++++
Sbjct: 1150 FCRCKPGFQRNMKN-RQCEDLNECLVFGTCSHQCINVEGSYKCVCDQNFQER-------N 1201
Query: 12517 KDCRAKGDAANVM-IGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYW 12693
C A+G V+ I D ++ + + H +++++ W
Sbjct: 1202 NTCIAEGSEDQVLYIANDTDILGFIYPFNYSGDHQQISHIEHNSRITGMDVYYQRDMIIW 1261
Query: 12694 IDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVV------PTAIAVDYTTGNLFIAAVS 12855
T + + H +K A G++ P IAVD+ GN++ S
Sbjct: 1262 -----STQFNPGGIFYKRIHGREKRQ---ANSGLICPEFKRPRDIAVDWVAGNIYWTDHS 1313
Query: 12856 ENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRI 13035
T + I N G + +G +++ +P A+ P G +
Sbjct: 1314 RMHWFSYYTTHWTSLRYSI---NVGQL-----NGPNCTRLLTNMAGEPYAIAVNPKRGMM 1365
Query: 13036 CYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNI 13215
++ G H+ IE A MDGT R+I+V+ + PT +A+D RIYW D + + +V
Sbjct: 1366 YWTVVGDHSHIEEAAMDGTLRRILVQKNLQRPTGLAVDY-FSERIYWADFELSIIGSVLY 1424
Query: 13216 DGSERTTVVHDRH---IPYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGH 13386
DGS V + P+ +D+FE++IY ++ VQ KFG G V LA +++
Sbjct: 1425 DGSNSVVSVSSKQGLLHPHRIDIFEDYIYGAGPKNGVFRVQ-KFGHGSVEYLALNIDKTK 1483
Query: 13387 TVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTGFACLCPDGIVPQLDGSC 13542
V +S +Y + + C C LC+ PS G C+CP+G ++G+C
Sbjct: 1484 GVLISHRYKQ--LDLPNPCLDLACEFLCLLNPS-GATCVCPEGKY-LINGTC 1531
Score = 389 bits (999), Expect = e-105
Identities = 346/1296 (26%), Positives = 511/1296 (38%), Gaps = 201/1296 (15%)
Frame = +1
Query: 2083 YKCACPIGQKLV----NG-KRCIDSIDYLLFSSNKIVRGIFPEINEKALAEAVLPISPIS 2247
YKC C G ++ NG K D +L+ + + +R I + + L +
Sbjct: 313 YKCLCTDGYEIQPDNPNGCKSLSDEEPFLILADHHEIRKISTDGSNYTLLK--------- 363
Query: 2248 QRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGL-FSMSFDWIS 2424
+ + ++ D ++ D RI + + V HN + +++ DWI
Sbjct: 364 -QGLNNVIAIDFDYREEFIYWIDSSRPNGSRINRMCLNGSDIKVVHNTAVPNALAVDWIG 422
Query: 2425 KQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKGLLFYAEAMR 2604
K LY+ D + +EV K+ ++P LV ++L + P + + P G L++ +
Sbjct: 423 KNLYWSDTEKRIIEVSKLNG---LYPTILVSKRL----KFPRDLSLDPQAGYLYWIDCCE 475
Query: 2605 PAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVKL 2784
I R +DG N V+ T + RP + ID+ RL W D S MD ++ V
Sbjct: 476 YPHIGRVGMDGTNQSVVIETKISRPMALTIDYVNRRLYWADENHIEFSNMDGSHRHKVP- 534
Query: 2785 DIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGS-KIVREFGADERSIFSLKACSH 2961
+ D P +A+T+ +YIY+ + S+ R HK +G ++ + A I ++
Sbjct: 535 NQDIPGVIALTLFEDYIYWTDGKTKSLSRAHKTSGADRLSLIYSWHA----ITDIQVYHS 590
Query: 2962 QNQPIPDDSREHPCRASQ--CTQLCFATPSESHPNELEAKCACRQGFMINKENNHSCQKD 3135
QP D +H C + C+ LC P ++H CAC F + +N
Sbjct: 591 YRQP---DVSKHLCMINNGGCSHLCLLAPGKTHT------CACPTNFYLAADN------- 634
Query: 3136 PAEKIEQLCSSNST--QFQCKNGRCIPKEWKCD--------------------------- 3228
+ C SN T QF+CK +CIP WKCD
Sbjct: 635 ------RTCLSNCTASQFRCKTDKCIPFWWKCDTVDDCGDGSDEPDDCPEFRCQPGRFQC 688
Query: 3229 -------------GENDCLDESDEID-------------EKGDKCF-------------- 3288
GENDC D SDE++ K KC
Sbjct: 689 GTGLCALPAFICDGENDCGDNSDELNCDTHVCLSGQFKCTKNQKCIPVNLRCNGQDDCGD 748
Query: 3289 --HETECAENT-----IKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAK 3447
E +C EN+ +C+ TK CI + K C
Sbjct: 749 EEDERDCPENSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEA-----NCDKKTCGPH 803
Query: 3448 KFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNATCAANQFSCANGRCIPIYWLCDGD 3627
+FQC N+ CIP+ W+ E E C TC F CANG C+ + CDGD
Sbjct: 804 EFQCKNNNCIPDHWRCDSQNDCSDNSDE--ENCKPQTCTLKDFLCANGDCVSSRFWCDGD 861
Query: 3628 NDCYDGTDEDKERCPPVQCSALQFRCANG---------------------RQCVPLRNHX 3744
DC DG+DE R CS QFRC+NG + C P
Sbjct: 862 FDCADGSDE---RNCETSCSKDQFRCSNGQCIPAKWKCDGHEDCKYGEDEKSCEPASPTC 918
Query: 3745 XXXXXXXXXXXXXXXAVTAES----------------CTPDQFKCVSSGLCIPASWKXXX 3876
++ C DQF+C + CIP W
Sbjct: 919 SSREYICASDGCISASLKCNGEYDCADGSDEMDCVTECKEDQFRCKNKAHCIPIRWLCDG 978
Query: 3877 XXXXXXXSDEPKFGCTSGRQCSSDQFKCGNGRCILNNWLCDGENDCGDGSDES------- 4035
SDE G C +D+F C N C L+ W+CDGE+DCGD SDE+
Sbjct: 979 IHDCVDGSDEENCE-RGGNICRADEFLCNNSLCKLHFWVCDGEDDCGDNSDEAPDMCVKF 1037
Query: 4036 ------------------SERGC-----------------KTSMNARKCPFEHVACENDQ 4110
SE+ C K + AR C + AC N +
Sbjct: 1038 LCPSTRPHRCRNNRICLQSEQMCNGIDECGDNSDEDHCGGKLTYKARPCKKDEFACSNKK 1097
Query: 4111 ETCIPLHQLCDGKTHCPGGTDEGG-RCARD--LC--SADRAGCSFKCHNSPNGPICSCPF 4275
CIP+ CD C G+DE G R A C + + G C+ C C
Sbjct: 1098 --CIPMDLQCDRLDDCGDGSDEQGCRIAPTEYTCEDNVNPCGDDAYCNQIKTSVFCRCKP 1155
Query: 4276 GEQLVNKTK-CEPENECLDSSSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDT 4452
G Q K + CE NECL +CS +C + + + C CD+ ++ ++ +A+ +D
Sbjct: 1156 GFQRNMKNRQCEDLNECLVFGTCSHQCINVEGSYKCVCDQNFQ---ERNNTCIAEGSEDQ 1212
Query: 4453 RIYVSNRNRI--------YYSDHKLDNWHTFGAIVENAIALAWDSL--TDRIYWSD---- 4590
+Y++N I Y DH+ I N+ D D I WS
Sbjct: 1213 VLYIANDTDILGFIYPFNYSGDHQ-----QISHIEHNSRITGMDVYYQRDMIIWSTQFNP 1267
Query: 4591 --IREKKILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVDSSLN----------- 4731
I K+I + N+ + I IA+DWV N+YW D S
Sbjct: 1268 GGIFYKRIHGREKRQANSGL-ICPEFKRPRDIAVDWVAGNIYWTDHSRMHWFSYYTTHWT 1326
Query: 4732 ----TIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQNPCIERASMDGTD 4899
+I V L P LL + +P IAV+P++G+M+WT G + IE A+MDGT
Sbjct: 1327 SLRYSINVGQLNGPNCTRLLTNM-AGEPYAIAVNPKRGMMYWTVVGDHSHIEEAAMDGTL 1385
Query: 4900 RQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHAL 5079
R+I+V+ + P +A+DY ++R+Y+AD +L I V YDGS ++S + + HPH +
Sbjct: 1386 RRILVQKNLQRPTGLAVDYFSERIYWADFELSIIGSVLYDGSNSVVSVSSKQGLLHPHRI 1445
Query: 5080 AIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCST 5259
IFED +Y + + +V K+ +G+ EY + K GV+ H Q + NPC
Sbjct: 1446 DIFEDYIYGAGPKNGVFRV-QKFGHGSV-EYLALNIDKTKGVLISHRYKQLDLP-NPCLD 1502
Query: 5260 NPCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDA 5367
C LCLLN TC CP G+ L C DD+
Sbjct: 1503 LACEFLCLLNPSGA-TCVCPEGKYL--INGTCNDDS 1535
Score = 318 bits (816), Expect = 2e-84
Identities = 258/923 (27%), Positives = 397/923 (42%), Gaps = 26/923 (2%)
Frame = +1
Query: 7228 PCTQLCFATPGTQTPTCSCARGV---------LKGRTCEEPDTYIMFSDGDKIIDVAIEP 7380
PC+Q C T GT C C G K + EEP +++ +D +I ++
Sbjct: 301 PCSQQCINTYGTYK--CLCTDGYEIQPDNPNGCKSLSDEEP--FLILADHHEIRKIST-- 354
Query: 7381 DVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVES-PVGVNISWFSMNNAENPRLVFGA 7557
D LK ++N+ D D +Y++ S P G I+ +N ++ V
Sbjct: 355 DGSNYTLLKQG---LNNVIAIDFDYREEFIYWIDSSRPNGSRINRMCLNGSDIK--VVHN 409
Query: 7558 SKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTIASGDWTYA--LAI 7731
+ P+A + +DW+ + +Y++ + G + + + S + L++
Sbjct: 410 TAVPNA--------LAVDWIGKNLYWSDTEKRIIEVSKLNGLYPTILVSKRLKFPRDLSL 461
Query: 7732 DPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVDFRNQKIYW 7911
DP +G L+W D P I R + G ++ V++ IS P A+ +D+ N+++YW
Sbjct: 462 DPQAGYLYWIDC-------CEYPHIGRVGMDGTNQSVVIETKISRPMALTIDYVNRRLYW 514
Query: 7912 ADVNRLNIEVADYDGQNRKVIASGY--RAKSLDIWDRWLYMSDPLSNGVFRIDKESGSGL 8085
AD N +IE ++ DG +R + + +L +++ ++Y +D + + R K SG+
Sbjct: 515 ADEN--HIEFSNMDGSHRHKVPNQDIPGVIALTLFEDYIYWTDGKTKSLSRAHKTSGADR 572
Query: 8086 ENVVSDRRIPGALRVFAS--ESDVRTRNQVCNALTSQLCKTDNGGCDQLCTVVADDIGLA 8259
+++ ++V+ S + DV + LC +NGGC LC LA
Sbjct: 573 LSLIYSWHAITDIQVYHSYRQPDV----------SKHLCMINNGGCSHLCL-------LA 615
Query: 8260 ASKVQ-CSCNDTYELVQEPGKDYPTQCVLRGSNSEPAKECLPPYNFQCGDGSCILLGATC 8436
K C+C PT L N C F+C CI C
Sbjct: 616 PGKTHTCAC--------------PTNFYLAADNRTCLSNCTAS-QFRCKTDKCIPFWWKC 660
Query: 8437 DSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHIDDCGDGSDELDCPSAV 8616
D+ DC D SDE P+ C C C C A C+ +DCGD SDEL+C + V
Sbjct: 661 DTVDDCGDGSDE-PDDCPEFRCQPGRFQCGTGLCALPAFICDGENDCGDNSDELNCDTHV 719
Query: 8617 ACAEGTFPCS-NGHCINQTKVCDGHNDCHDEQVSDESLATCPGLPIDCRGVKVRCPNTNI 8793
C G F C+ N CI C+G +DC DE E CP C +C T
Sbjct: 720 -CLSGQFKCTKNQKCIPVNLRCNGQDDCGDE----EDERDCP--ENSCSPDYFQCKTTKH 772
Query: 8794 CIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWD 8973
CI +CD DC D +DE C + C H +C + CIP+ W+CD NDCSD D
Sbjct: 773 CISKLWVCDEDPDCADASDEAN--CDKKTCGPHEFQCKNNNCIPDHWRCDSQNDCSDNSD 830
Query: 8974 ETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTD 9153
E NC + + D+L C N C+S F C +C+
Sbjct: 831 E--ENCKP---QTCTLKDFL--CANGDCVSSRF---WCDGDFDCADGSDERNC-ETSCSK 879
Query: 9154 QEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECNKGEFRCSNQH 9333
+F C++ +CIP W CDG C GEDE + C+ C+ E+ C++
Sbjct: 880 DQFRCSNG--------QCIPAKWKCDGHEDCKYGEDEKS--CEPASPTCSSREYICASDG 929
Query: 9334 CIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCANH-KCVPNSWKCDGNDDCEDGSD 9510
CI ++ +C+G+ DC DGSDE +C + C+ D F+C N C+P W CDG DC DGSD
Sbjct: 930 CISASLKCNGEYDCADGSDE-MDCV-TECKEDQFRCKNKAHCIPIRWLCDGIHDCVDGSD 987
Query: 9511 EKDCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDES-SLCFIDECSL 9687
E++C + + C +F C + C VCD DC D SDE+ +C C
Sbjct: 988 EENCERG------GNICRADEFLCNNSLCKLHFWVCDGEDDCGDNSDEAPDMCVKFLCPS 1041
Query: 9688 AEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSC-----HNVNECYEGISGCS-QKCDD 9849
C + ++ C+ + D SD+ C + C + CS +KC
Sbjct: 1042 TRPHRCRNNRICLQSEQMCNGIDECG-DNSDEDHCGGKLTYKARPCKKDEFACSNKKCIP 1100
Query: 9850 KIGSYKCGCVDGYQLSSDDHSCK 9918
+C +D SD+ C+
Sbjct: 1101 M--DLQCDRLDDCGDGSDEQGCR 1121
Score = 310 bits (793), Expect = 9e-82
Identities = 202/656 (30%), Positives = 312/656 (46%), Gaps = 10/656 (1%)
Frame = +1
Query: 3427 KPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNATCAANQFSCANGRCIPI 3606
K C F C + RCI W + E +++C+ NQF+C+ +CI
Sbjct: 3 KHKCEENYFSCPSGRCILNTW---ICDGQKDCEDGRDEFHCDSSCSWNQFACSAQKCISK 59
Query: 3607 YWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQCVPLRNHXXXXXXXXXXXXXXX 3786
+W+CDG++DC DG DE C + C+A F C R CVP
Sbjct: 60 HWICDGEDDCGDGLDESDSICGAITCAADMFSCQGSRACVPRHWLCDGERDCPDGSDELS 119
Query: 3787 XAVTA--ESCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDE-PKFGCTSGRQCSSDQFK 3957
A A +C + F C + +CIP + SDE P+ G RQC +++F
Sbjct: 120 TAGCAPNNTCDENAFMC-HNKVCIPKQFVCDHDDDCGDGSDESPQCGY---RQCGTEEFS 175
Query: 3958 CGNGRCILN-NWLCDGENDCGDGSDESS-ERGCKTSMNARKCPFEHVACENDQETCIPLH 4131
C +GRC+LN W CDG+ DC D SDE+ CK++ + C C+N + CIP
Sbjct: 176 CADGRCLLNTQWQCDGDFDCPDHSDEAPLNPKCKSA--XQSCNSSFFMCKNGR--CIPSG 231
Query: 4132 QLCDGKTHCPGGTDEGGRCARDLCSADRAGCSFKCHNSPNGPICSCPFGEQLVNKTK-CE 4308
LCD K C G+DE + S +GCS C + P C C G QL + K C
Sbjct: 232 GLCDNKDDCGDGSDERNCHINECLSKKVSGCSQDCQDLPVSYKCKCWPGFQLKDDGKTCV 291
Query: 4309 PENECLDSSSCSQRCKDEKHGFTCSCDEGYELDVDK-RTCKVADNVKDTRIYVSNRNRIY 4485
+EC CSQ+C + + C C +GYE+ D CK + ++ + +++ + I
Sbjct: 292 DIDECSSGFPCSQQCINTYGTYKCLCTDGYEIQPDNPNGCKSLSD-EEPFLILADHHEIR 350
Query: 4486 YSDHKLDNWHTFGAIVENAIALAWDSLTDRIYWSDIREKKILSANRNGTNAT-VFIADGL 4662
N+ + N IA+ +D + IYW D NR N + + +
Sbjct: 351 KISTDGSNYTLLKQGLNNVIAIDFDYREEFIYWIDSSRPNGSRINRMCLNGSDIKVVHNT 410
Query: 4663 DITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMF 4842
+ +A+DW+G+NLYW D+ IEV+ L + T+LV + + PR +++DP+ G ++
Sbjct: 411 AVPNALAVDWIGKNLYWSDTEKRIIEVSKL-NGLYPTILVSKRLKFPRDLSLDPQAGYLY 469
Query: 4843 WTDWGQNPCIERASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDG 5022
W D + P I R MDGT++ ++++TKI P + +DY R+Y+AD + I+F N DG
Sbjct: 470 WIDCCEYPHIGRVGMDGTNQSVVIETKISRPMALTIDYVNRRLYWADE--NHIEFSNMDG 527
Query: 5023 SGRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALG 5202
S R +V ++ + AL +FED +Y++D + + L K +G +++
Sbjct: 528 SHRHKV--PNQDIPGVIALTLFEDYIYWTDGKTKSLSRAHK-TSGADRLSLIYSWHAITD 584
Query: 5203 VVAVHPVLQPVIKNNPCSTN--PCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDD 5364
+ H QP + + C N CSHLCLL T TC CP L A + C+ +
Sbjct: 585 IQVYHSYRQPDVSKHLCMINNGGCSHLCLLAPGKTHTCACPTNFYLAADNRTCLSN 640
Score = 282 bits (722), Expect = 1e-73
Identities = 206/752 (27%), Positives = 311/752 (40%), Gaps = 83/752 (11%)
Frame = +1
Query: 139 NTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHS 318
N C DF C +G C+ + + C DQ++C +
Sbjct: 833 NCKPQTCTLKDFLCANGDCVSSRFWCDGDFDCADGSDERNC-ETSCSKDQFRCS-----N 886
Query: 319 VSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCR 498
CI +CD DC G DEK C ++ CSS+ +DG C S KC+G+YDC
Sbjct: 887 GQCIPAKWKCDGHEDCKYGEDEKSCEPASPTCSSREYICASDG--CISASLKCNGEYDCA 944
Query: 499 DLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEF--KKCT 672
D SDE D T C + QFRC +K CI W+CDG DC DGSDE + CE C
Sbjct: 945 DGSDEMDCV----TECKEDQFRCKNKAHCIPIRWLCDGIHDCVDGSDE-ENCERGGNICR 999
Query: 673 ANEFQCKNKRCQPRKFRCDYYDDCGDNSDE--DECGEYRCPPGK-WNCPGTGHCIDQLKL 843
A+EF C N C+ + CD DDCGDNSDE D C ++ CP + C C+ ++
Sbjct: 1000 ADEFLCNNSLCKLHFWVCDGEDDCGDNSDEAPDMCVKFLCPSTRPHRCRNNRICLQSEQM 1059
Query: 844 CDGSKDCADGADEQQCSQNL-------------CPSLGC------------------QAG 930
C+G +C D +DE C L C + C + G
Sbjct: 1060 CNGIDECGDNSDEDHCGGKLTYKARPCKKDEFACSNKKCIPMDLQCDRLDDCGDGSDEQG 1119
Query: 931 C-----------HPSPHGGE-----------CTCPSGYKLDDRFHRTCSDINECAEFGYC 1044
C + +P G + C C G++ + + +R C D+NEC FG C
Sbjct: 1120 CRIAPTEYTCEDNVNPCGDDAYCNQIKTSVFCRCKPGFQRNMK-NRQCEDLNECLVFGTC 1178
Query: 1045 DQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGY-CVSNNADKMKLFVARREGL-- 1215
C N + C C N R C++ ++ L++A +
Sbjct: 1179 SHQCINVEGSYKCVC--------------DQNFQERNNTCIAEGSEDQVLYIANDTDILG 1224
Query: 1216 --YRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSA-FSADVDDEGEISQI 1386
Y N +++ + I G+D Y I W+ + F + +
Sbjct: 1225 FIYPFNYSGDHQQISHIEHNSRITGMDVYYQRDMIIWSTQFNPGGIFYKRIHGREKRQAN 1284
Query: 1387 KKLSLKSLVYPRCLAVDWITNTLYIIESGSRR---------------IDVSSYDGERRTV 1521
L PR +AVDW+ +Y + I+V +G T
Sbjct: 1285 SGLICPEFKRPRDIAVDWVAGNIYWTDHSRMHWFSYYTTHWTSLRYSINVGQLNGPNCTR 1344
Query: 1522 LLADGLTLPLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDI 1692
LL + P IA++P RG M++T + +E AAMDGT RR LV + + +G+ VD
Sbjct: 1345 LLTNMAGEPYAIAVNPKRGMMYWTVVGDHSHIEEAAMDGTLRRILVQKNLQRPTGLAVDY 1404
Query: 1693 TAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQ 1872
++R+YW D ++ + S+ Y G++ + + HP + +F+ Y+Y + GV +
Sbjct: 1405 FSERIYWADFELSIIGSVLYDGSNSVVSVSSKQGLLHPHRIDIFEDYIYGAG-PKNGVFR 1463
Query: 1873 VEKFG-SDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCI 2049
V+KFG + L N + G+ H Q + + NPC + CE +C+
Sbjct: 1464 VQKFGHGSVEYLALNIDKT---KGVLISHRYKQ----------LDLPNPCLDLACEFLCL 1510
Query: 2050 LSKDNGGFGVGYKCACPIGQKLVNGKRCIDSI 2145
L+ G C CP G+ L+NG DS+
Sbjct: 1511 LNPS------GATCVCPEGKYLINGTCNDDSL 1536
Score = 282 bits (721), Expect = 2e-73
Identities = 197/673 (29%), Positives = 304/673 (44%), Gaps = 25/673 (3%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKS--DQWQCDTY-TWHSVSC 327
C EN F C G+CI W C+ D++ CD+ +W+ +C
Sbjct: 6 CEENYFSCPSGRCILNTWICDG--------------QKDCEDGRDEFHCDSSCSWNQFAC 51
Query: 328 -----IAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYD 492
I+++ CD DC DG DE D + C++ ++F C R C CDG+ D
Sbjct: 52 SAQKCISKHWICDGEDDCGDGLDESDSICGAITCAA-DMFSCQGSRACVPRHWLCDGERD 110
Query: 493 CRDLSDEKDS--CSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKK 666
C D SDE + C+ N+T C + F C +K CI K +VCD DC DGSDE C +++
Sbjct: 111 CPDGSDELSTAGCAPNNT-CDENAFMCHNKV-CIPKQFVCDHDDDCGDGSDESPQCGYRQ 168
Query: 667 CTANEFQCKNKRC-QPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGT------GHC 825
C EF C + RC +++CD DC D+SDE +C +C + G C
Sbjct: 169 CGTEEFSCADGRCLLNTQWQCDGDFDCPDHSDEAPLNP-KCKSAXQSCNSSFFMCKNGRC 227
Query: 826 IDQLKLCDGSKDCADGADEQQCSQNLCPS---LGCQAGCHPSPHGGECTCPSGYKLDDRF 996
I LCD DC DG+DE+ C N C S GC C P +C C G++L D
Sbjct: 228 IPSGGLCDNKDDCGDGSDERNCHINECLSKKVSGCSQDCQDLPVSYKCKCWPGFQLKDD- 286
Query: 997 HRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNA 1176
+TC DI+EC+ C Q C N + C C D + +Q ++ G C S +
Sbjct: 287 GKTCVDIDECSSGFPCSQQCINTYGTYKCLCT-DGYEIQPDNPNG---------CKSLSD 336
Query: 1177 DKMKLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTD--RLAHSAFS 1350
++ L +A + +++ + + K I IDFDY + I+W D R S +
Sbjct: 337 EEPFLILADHHEIRKISTDGSNYTLLKQGLNNVI-AIDFDYREEFIYWIDSSRPNGSRIN 395
Query: 1351 ADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLA 1530
+ +I + ++ P LAVDWI LY ++ R I+VS +G T+L++
Sbjct: 396 RMCLNGSDIKVVHNTAV-----PNALAVDWIGKNLYWSDTEKRIIEVSKLNGLYPTILVS 450
Query: 1531 DGLTLPLDIALDPLRGEMFFTNQLK---LEAAAMDGTNRRTLVNTHTHQVSGIVVDITAK 1701
L P D++LDP G +++ + + + MDGTN+ ++ T + + +D +
Sbjct: 451 KRLKFPRDLSLDPQAGYLYWIDCCEYPHIGRVGMDGTNQSVVIETKISRPMALTIDYVNR 510
Query: 1702 RVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEK 1881
R+YW D + +E + G+ R V +P L LF+ Y+YWTD + + K
Sbjct: 511 RLYWADE--NHIEFSNMDGSHRHKVPN--QDIPGVIALTLFEDYIYWTDGKTKSLSRAHK 566
Query: 1882 FGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKD 2061
+L + + + I YH QP + C+ N C +C+L+
Sbjct: 567 TSGADRLSLIYSWHAI--TDIQVYHSYRQPDVSKHLCM-------INNGGCSHLCLLAP- 616
Query: 2062 NGGFGVGYKCACP 2100
G + CACP
Sbjct: 617 ----GKTHTCACP 625
Score = 281 bits (720), Expect = 3e-73
Identities = 222/746 (29%), Positives = 316/746 (41%), Gaps = 17/746 (2%)
Frame = +1
Query: 11473 EDKQRCPTCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFR 11652
++K +C + F C SG+CI W+CD + DC D DE CS ++F
Sbjct: 1 QNKHKC----EENYFSCP-SGRCILNTWICDGQKDCEDGRDEFHCDSS-----CSWNQFA 50
Query: 11653 CNDGKCIPGSKVCDGTIQCSDGLDESQ--CTLRRCLPGHRQCDDG-TCIAEHKWCDRKKD 11823
C+ KCI +CDG C DGLDES C C C C+ H CD ++D
Sbjct: 51 CSAQKCISKHWICDGEDDCGDGLDESDSICGAITCAADMFSCQGSRACVPRHWLCDGERD 110
Query: 11824 CPNAADELHCEDVS-RRTCSPFEFECANSVCIPRKFMXXXXXXXXXXSDETSSECRSAQC 12000
CP+ +DEL + TC F C N VCIP++F+ SDE S +C QC
Sbjct: 111 CPDGSDELSTAGCAPNNTCDENAFMCHNKVCIPKQFVCDHDDDCGDGSDE-SPQCGYRQC 169
Query: 12001 DPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSFSEYGDCSSDQFKCANGK 12180
F CA R LN C+G DC D SDE S C+S F C NG+
Sbjct: 170 GTE-EFSCADGRCLLNTQWQCDGDFDCP--DHSDEAPLNPKCKSAXQSCNSSFFMCKNGR 226
Query: 12181 CVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNN-GGCKHICTDVRDGFYCHCRDG 12357
C+ CD KDDCGD SDE C + E GC C D+ + C C G
Sbjct: 227 CIPSGGLCDNKDDCGDGSDERNCHIN------ECLSKKVSGCSQDCQDLPVSYKCKCWPG 280
Query: 12358 FRPDPQSPKECIDIDECAGNNTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKG 12537
F+ K C+DIDEC+ C+Q C+NT G+Y C C + YE + C++
Sbjct: 281 FQLKDDG-KTCVDIDECSSGFPCSQQCINTYGTYKCLCTDGYE----IQPDNPNGCKSLS 335
Query: 12538 DAANVMIGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERTI 12717
D +I AD ++ + G+N R+E +YWID S
Sbjct: 336 DEEPFLILADHHEIR-KISTDGSN---YTLLKQGLNNVIAIDFDYREEFIYWIDSSRPNG 391
Query: 12718 YR--SAIANGNQSHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAVSENIENGLVTARK 12891
R NG+ D+ VP A+AVD+ NL+ + + I
Sbjct: 392 SRINRMCLNGS--------DIKVVHNTAVPNALAVDWIGKNLYWSDTEKRI--------- 434
Query: 12892 KRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIE 13071
I V +G Y +V+ L+ P L P AG + + D + I
Sbjct: 435 --------------IEVSKLNGLYPTILVSKRLKFPRDLSLDPQAGYLYWIDCCEYPHIG 480
Query: 13072 CADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDR 13251
MDGT++ ++++ + P ++ ID R+YW D + ++ N+DGS R V + +
Sbjct: 481 RVGMDGTNQSVVIETKISRPMALTIDY-VNRRLYWADENH--IEFSNMDGSHRHKVPN-Q 536
Query: 13252 HIP--YAVDVFENHIYWLSRESKTLYVQDKF-GRGRVSVLAS-----DLEDGHTVRVSQK 13407
IP A+ +FE++IYW ++K+L K G R+S++ S D++ H+ R
Sbjct: 537 DIPGVIALTLFEDYIYWTDGKTKSLSRAHKTSGADRLSLIYSWHAITDIQVYHSYR---- 592
Query: 13408 YAKDTQRTVSGCERAQCSHLCVSLPSTGFACLCPDGIVPQLDG-SCATQHVEALTMPKQC 13584
D + + CSHLC+ P C CP D +C + + K
Sbjct: 593 -QPDVSKHLCMINNGGCSHLCLLAPGKTHTCACPTNFYLAADNRTCLSNCTASQFRCKTD 651
Query: 13585 KCTN-GGKCRLDGSCECTSDFEGDQC 13659
KC KC C SD E D C
Sbjct: 652 KCIPFWWKCDTVDDCGDGSD-EPDDC 676
Score = 173 bits (439), Expect = 1e-40
Identities = 112/322 (34%), Positives = 146/322 (44%), Gaps = 1/322 (0%)
Frame = +1
Query: 124 ISASVNTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXX-PHPGCKSDQWQCD 300
++A T S C + FRC KCI W P C+ ++QC
Sbjct: 630 LAADNRTCLSNCTASQFRCKTDKCIPFWWKCDTVDDCGDGSDEPDDCPEFRCQPGRFQCG 689
Query: 301 TYTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCD 480
T C CD DC D SDE +C T C S F C ++C V+ +C+
Sbjct: 690 TGL-----CALPAFICDGENDCGDNSDELNC--DTHVCLSGQ-FKCTKNQKCIPVNLRCN 741
Query: 481 GKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEF 660
G+ DC D DE+D C N +C F+C CI K WVCD DCAD SDE + C+
Sbjct: 742 GQDDCGDEEDERD-CPEN--SCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEAN-CDK 797
Query: 661 KKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLK 840
K C +EFQCKN C P +RCD +DC DNSDE+ C C + C G C+
Sbjct: 798 KTCGPHEFQCKNNNCIPDHWRCDSQNDCSDNSDEENCKPQTCTLKDFLC-ANGDCVSSRF 856
Query: 841 LCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDIN 1020
CDG DCADG+DE+ C + Q C G+C P+ +K D H C
Sbjct: 857 WCDGDFDCADGSDERNCETSCSKD---QFRC----SNGQC-IPAKWKCDG--HEDC---- 902
Query: 1021 ECAEFGYCDQLCANHRPGFTCS 1086
++G ++ C P TCS
Sbjct: 903 ---KYGEDEKSCEPASP--TCS 919
Score = 147 bits (371), Expect = 7e-33
Identities = 111/402 (27%), Positives = 150/402 (36%), Gaps = 16/402 (3%)
Frame = +1
Query: 11248 ERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXETPECAQIECKKGWTRCSSSYRCIPN 11427
+ C F C + +CI W E C CS+ +CI
Sbjct: 3 KHKCEENYFSCPSGRCILNTWICDGQKDCEDGRDEFH--CDSSCSWNQFACSAQ-KCISK 59
Query: 11428 WAFCNGQDDCRDNSDEDKQRCPTCDDVGE-FRCATSGKCIPRRWMCDTENDCGDNSDELD 11604
C+G+DDC D DE C + F C S C+PR W+CD E DC D SDEL
Sbjct: 60 HWICDGEDDCGDGLDESDSICGAITCAADMFSCQGSRACVPRHWLCDGERDCPDGSDELS 119
Query: 11605 ASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDES-QCTLRRCLPGHRQCDDG 11781
+ C E+ F C++ CIP VCD C DG DES QC R+C C DG
Sbjct: 120 TAGCAPNNTCDENAFMCHNKVCIPKQFVCDHDDDCGDGSDESPQCGYRQCGTEEFSCADG 179
Query: 11782 TCIAEHKW-CDRKKDCPNAADEL----HCEDVSRRTCSPFEFECANSVCIPRKFMXXXXX 11946
C+ +W CD DCP+ +DE C+ + ++C+ F C N CIP +
Sbjct: 180 RCLLNTQWQCDGDFDCPDHSDEAPLNPKCKS-AXQSCNSSFFMCKNGRCIPSGGL----- 233
Query: 11947 XXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDE---HLSM 12117
C+ +DCG D SDE H++
Sbjct: 234 --------------------------------------CDNKDDCG--DGSDERNCHINE 253
Query: 12118 CSSFSEYGDCSSD------QFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCE 12279
C S + CS D +KC KC G D C D + CS
Sbjct: 254 CLS-KKVSGCSQDCQDLPVSYKC---KCWPGFQLKDDGKTCVDIDE---CS--------- 297
Query: 12280 AFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDE 12405
+ C C + + C C DG+ P +P C + +
Sbjct: 298 ---SGFPCSQQCINTYGTYKCLCTDGYEIQPDNPNGCKSLSD 336
Score = 141 bits (355), Expect = 5e-31
Identities = 111/352 (31%), Positives = 150/352 (42%), Gaps = 18/352 (5%)
Frame = +1
Query: 8392 FQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHID 8571
F C G CIL CD + DC D DE +C++ SC + C+ ++CI C+ D
Sbjct: 11 FSCPSGRCILNTWICDGQKDCEDGRDEF--HCDS-SCSWNQFACSAQKCISKHWICDGED 67
Query: 8572 DCGDGSDELD-CPSAVACAEGTFPCSNGH-CINQTKVCDGHNDCHDEQVSDESLATCPGL 8745
DCGDG DE D A+ CA F C C+ + +CDG DC D + L+T
Sbjct: 68 DCGDGLDESDSICGAITCAADMFSCQGSRACVPRHWLCDGERDCPD---GSDELSTAGCA 124
Query: 8746 PID-CRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCI 8922
P + C C N +CI +CD DDCGD +DE+ C +QC C GRC+
Sbjct: 125 PNNTCDENAFMCHN-KVCIPKQFVCDHDDDCGDGSDESPQ-CGYRQCGTEEFSCADGRCL 182
Query: 8923 PET-WQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXX 9099
T WQCDGD DC D DE N + + C + F C N +CI +
Sbjct: 183 LNTQWQCDGDFDCPDHSDEAPLNPKCKSAXQSCNSSF-FMCKNGRCIPSGGLCDNKDDCG 241
Query: 9100 XXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKY--ECIPRAWLCDGDVTCAGGEDESTE 9273
+ H N + + C+ + + Y +C P L D TC
Sbjct: 242 DGSDERNCH--INECLSKKVSGCSQDCQDLPVSYKCKCWPGFQLKDDGKTC--------- 290
Query: 9274 LCKTEKKECNKGEFRCSNQHCI--HSTWEC----------DGDNDCLDGSDE 9393
+ EC+ G F CS Q CI + T++C D N C SDE
Sbjct: 291 ---VDIDECSSG-FPCS-QQCINTYGTYKCLCTDGYEIQPDNPNGCKSLSDE 337
Score = 139 bits (351), Expect = 2e-30
Identities = 109/376 (28%), Positives = 174/376 (45%), Gaps = 16/376 (4%)
Frame = +1
Query: 6235 SSGHPCHINNGNCDHICIPLMFAQRTCTCANGYV--KDGQTSCKLF--DESFVIVATKTK 6402
SSG PC CI + C C +GY D CK +E F+I+A +
Sbjct: 297 SSGFPC-------SQQCINT-YGTYKCLCTDGYEIQPDNPNGCKSLSDEEPFLILADHHE 348
Query: 6403 VIGYPIDETQSKGVAMEPIGGLSITGVDYDYESKTIYVAEASGINKG-ITAYTIGESSPR 6579
+ T + G ++ +D+DY + IY ++S N I + S +
Sbjct: 349 IRKI---STDGSNYTLLKQGLNNVIAIDFDYREEFIYWIDSSRPNGSRINRMCLNGSDIK 405
Query: 6580 AVIRDSIGSLTIKSLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSI 6759
V ++ + +LA+DWI N+Y+ D E+ IEVSKL+G Y IL++ + + P +
Sbjct: 406 VVHNTAVPN----ALAVDWIGKNLYW--SDTEKRIIEVSKLNGLYPTILVSKRLKFPRDL 459
Query: 6760 AVDPVSRYLYWADQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSD--- 6930
++DP + YLYW D + P I R +DG+ + V++ + I+ P L +D ++ +YW+D
Sbjct: 460 SLDPQAGYLYWIDCCEYPHIGRVGMDGTNQSVVIETKISRPMALTIDYVNRRLYWADENH 519
Query: 6931 ---AKMDGIYRVRSTGGTPELVRSDIASAAGVALHGQNMYWTDNRLEKLFRA--TSKPNQ 7095
+ MDG +R ++ DI + L +YWTD + + L RA TS ++
Sbjct: 520 IEFSNMDGSHR-------HKVPNQDIPGVIALTLFEDYIYWTDGKTKSLSRAHKTSGADR 572
Query: 7096 TSLLLSPTTVAASLKDIGDVAVFSSNNQPRASSPCQITDNLRKSPCTQLCFATPGTQTPT 7275
SL+ S I D+ V+ S QP S + +N C+ LC PG +T T
Sbjct: 573 LSLIY-------SWHAITDIQVYHSYRQPDVSKHLCMINN---GGCSHLCLLAPG-KTHT 621
Query: 7276 CSCARG---VLKGRTC 7314
C+C RTC
Sbjct: 622 CACPTNFYLAADNRTC 637
Score = 135 bits (339), Expect = 4e-29
Identities = 85/270 (31%), Positives = 119/270 (43%), Gaps = 27/270 (10%)
Frame = +1
Query: 304 YTWHSVSCIAEYQR------CDNITDCADGSDEKDC---PASTVDCSSQ-NVFMCADGRQ 453
Y+WH+++ I Y ++ +G C P T C+ N ++ AD R
Sbjct: 577 YSWHAITDIQVYHSYRQPDVSKHLCMINNGGCSHLCLLAPGKTHTCACPTNFYLAADNRT 636
Query: 454 CFDVSK----------------KCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQC 585
C KCD DC D SDE D C C +F+C C
Sbjct: 637 CLSNCTASQFRCKTDKCIPFWWKCDTVDDCGDGSDEPDDCPEFR--CQPGRFQCGTGL-C 693
Query: 586 IQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQC-KNKRCQPRKFRCDYYDDCGDNSDE 762
+++CDG DC D SDE + C+ C + +F+C KN++C P RC+ DDCGD DE
Sbjct: 694 ALPAFICDGENDCGDNSDELN-CDTHVCLSGQFKCTKNQKCIPVNLRCNGQDDCGDEEDE 752
Query: 763 DECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPS 942
+C E C P + C T HCI +L +CD DCAD +DE C + C
Sbjct: 753 RDCPENSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEANCDKKTC-----------G 801
Query: 943 PHGGECTCPSGYKLDDRFHRTCSDINECAE 1032
PH E C + + D H C N+C++
Sbjct: 802 PH--EFQCKNNNCIPD--HWRCDSQNDCSD 827
Score = 107 bits (268), Expect = 7e-21
Identities = 120/555 (21%), Positives = 205/555 (36%), Gaps = 25/555 (4%)
Frame = +1
Query: 148 SSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSC 327
++ C+EN F C++ CI ++
Sbjct: 126 NNTCDENAFMCHNKVCIPKQFV-------------------------------------- 147
Query: 328 IAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLS 507
CD+ DC DGSDE C ++ F CADGR + +CDG +DC D S
Sbjct: 148 ------CDHDDDCGDGSDESP-QCGYRQCGTEE-FSCADGRCLLNTQWQCDGDFDCPDHS 199
Query: 508 DE---KDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTAN 678
DE C +C F C + +CI +CD DC DGSDE + C +C +
Sbjct: 200 DEAPLNPKCKSAXQSCNSSFFMCKN-GRCIPSGGLCDNKDDCGDGSDERN-CHINECLSK 257
Query: 679 EFQCKNKRCQ--PRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDG 852
+ ++ CQ P ++C +C PG +L D
Sbjct: 258 KVSGCSQDCQDLPVSYKC------------------KCWPG-------------FQLKDD 286
Query: 853 SKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAE 1032
K C D +CS C C + +C C GY++ C +++
Sbjct: 287 GKTC---VDIDECSS----GFPCSQQCINTYGTYKCLCTDGYEIQPDNPNGCKSLSDEEP 339
Query: 1033 FGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREG 1212
F + A+H S G +TL + G +N+ F R E
Sbjct: 340 F----LILADHHEIRKISTDGSNYTLLKQ---GLNNVIAID------------FDYREEF 380
Query: 1213 LYRLNPKNPD-----------EEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADV 1359
+Y ++ P+ ++K + + + D+ + ++W+
Sbjct: 381 IYWIDSSRPNGSRINRMCLNGSDIKVVHNTAVPNALAVDWIGKNLYWS------------ 428
Query: 1360 DDEGEISQIKKLS--------LKSLVYPRCLAVDWITNTLYIIESGS-RRIDVSSYDGER 1512
D E I ++ KL+ K L +PR L++D LY I+ I DG
Sbjct: 429 DTEKRIIEVSKLNGLYPTILVSKRLKFPRDLSLDPQAGYLYWIDCCEYPHIGRVGMDGTN 488
Query: 1513 RTVLLADGLTLPLDIALDPLRGEMFFTNQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDI 1692
++V++ ++ P+ + +D + +++ ++ +E + MDG++R + N V I + +
Sbjct: 489 QSVVIETKISRPMALTIDYVNRRLYWADENHIEFSNMDGSHRHKVPNQDIPGV--IALTL 546
Query: 1693 TAKRVYWVDPKVDRL 1737
+YW D K L
Sbjct: 547 FEDYIYWTDGKTKSL 561
Score = 101 bits (251), Expect = 6e-19
Identities = 67/205 (32%), Positives = 87/205 (41%), Gaps = 15/205 (7%)
Frame = +1
Query: 3160 CSSNSTQFQCKNGRCIPKEWKCDGENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKK 3339
CS N QF C +CI K W CDGE+DC D +DE C T CA + C+ ++
Sbjct: 44 CSWN--QFACSAQKCISKHWICDGEDDC---GDGLDESDSICGAIT-CAADMFSCQGSRA 97
Query: 3340 CIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPV----------CAAKKFQCDNHRCIPEQW 3489
C+P + C DG + C F C N CIP+Q+
Sbjct: 98 CVPRHWLCDGE-----------RDCPDGSDELSTAGCAPNNTCDENAFMCHNKVCIPKQF 146
Query: 3490 KXXXXXXXXXXXXEKLEMCGNATCAANQFSCANGRC-IPIYWLCDGDNDCYDGTDE---- 3654
E CG C +FSCA+GRC + W CDGD DC D +DE
Sbjct: 147 VCDHDDDCGDGSDES-PQCGYRQCGTEEFSCADGRCLLNTQWQCDGDFDCPDHSDEAPLN 205
Query: 3655 DKERCPPVQCSALQFRCANGRQCVP 3729
K + C++ F C NGR C+P
Sbjct: 206 PKCKSAXQSCNSSFFMCKNGR-CIP 229
Score = 95.9 bits (237), Expect = 3e-17
Identities = 92/378 (24%), Positives = 159/378 (41%), Gaps = 9/378 (2%)
Frame = +1
Query: 5251 CSTN-PCSHLCLLNNKNTFTCKCPMGEKL---DASGKKCIDDAKPFLVIIQKTNVFGIEM 5418
CS+ PCS C+ N T+ C C G ++ + +G K + D +PFL++ + I
Sbjct: 296 CSSGFPCSQQCI-NTYGTYKCLCTDGYEIQPDNPNGCKSLSDEEPFLILADHHEIRKIST 354
Query: 5419 NSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRST 5598
+ ++ + GL N +D E ++ ++ + S I R
Sbjct: 355 DGSNYT--------LLKQGLNNVIAIDFDYREEFIYWIDSSR--------PNGSRINRMC 398
Query: 5599 VNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVILSNDQS 5778
+NG + + ++AVP+ L DW G+NL + + IE+ + G Y ++++S
Sbjct: 399 LNGSDIKVVHNTAVPN---ALAVDWIGKNLYWSDTEKRIIEVSKLNGL-YPTILVSKRLK 454
Query: 5779 XXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAID 5958
GY++W+D + R G+DG+N V+ ++ + ID
Sbjct: 455 FPRDLSLDPQA-----GYLYWIDC---CEYPHIGRVGMDGTNQSVVIETKISRPMALTID 506
Query: 5959 TTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAFDSIEVA 6138
N R+Y+++ S++ DG RH V + L + D +++ D S+ A
Sbjct: 507 YVNRRLYWADENHIEFSNM--DGSHRHKVPNQDIPGVIALTLFEDYIYWTDGKTKSLSRA 564
Query: 6139 --TINGD--SQPPQWTHFKKDVENLANIKALQPRASSSGHPCHINNGNCDHICIPLMFAQ 6306
T D S W H D++ + + QP S H C INNG C H+C+
Sbjct: 565 HKTSGADRLSLIYSW-HAITDIQVYHSYR--QPDVSK--HLCMINNGGCSHLCLLAPGKT 619
Query: 6307 RTCTC-ANGYVKDGQTSC 6357
TC C N Y+ +C
Sbjct: 620 HTCACPTNFYLAADNRTC 637
Score = 78.6 bits (192), Expect = 4e-12
Identities = 65/254 (25%), Positives = 106/254 (41%), Gaps = 19/254 (7%)
Frame = +1
Query: 6265 GNCDHICIPLMFAQRTCTCANGYVKDGQTSCKLFDESFVI-VATKTKVIG--YPIDETQS 6435
G C H CI + + + C C + + T E V+ +A T ++G YP + +
Sbjct: 1176 GTCSHQCINVEGSYK-CVCDQNFQERNNTCIAEGSEDQVLYIANDTDILGFIYPFNYSGD 1234
Query: 6436 KGVAMEPIGGLSITGVDYDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTI 6615
ITG+D Y+ I + + N G Y + +
Sbjct: 1235 HQQISHIEHNSRITGMDVYYQRDMIIWS--TQFNPGGIFYKRIHGREKRQANSGLICPEF 1292
Query: 6616 K---SLAIDWINYNMYFINHD-------------AERTNIEVSKLDGTYRKILLTTKTET 6747
K +A+DW+ N+Y+ +H + R +I V +L+G LLT
Sbjct: 1293 KRPRDIAVDWVAGNIYWTDHSRMHWFSYYTTHWTSLRYSINVGQLNGPNCTRLLTNMAGE 1352
Query: 6748 PSSIAVDPVSRYLYWADQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWS 6927
P +IAV+P +YW G I+ + +DG+ R ++V + PT L VD S+ IYW+
Sbjct: 1353 PYAIAVNPKRGMMYWTVVGDHSHIEEAAMDGTLRRILVQKNLQRPTGLAVDYFSERIYWA 1412
Query: 6928 DAKMDGIYRVRSTG 6969
D ++ I V G
Sbjct: 1413 DFELSIIGSVLYDG 1426
Score = 69.7 bits (169), Expect = 2e-09
Identities = 51/192 (26%), Positives = 90/192 (46%), Gaps = 22/192 (11%)
Frame = +1
Query: 7579 EIRHISDMKLDWLTQKIYFT-----------TGRGGKVMAIDTAGE-------HLSTIAS 7704
E + D+ +DW+ IY+T T + G+ L T +
Sbjct: 1291 EFKRPRDIAVDWVAGNIYWTDHSRMHWFSYYTTHWTSLRYSINVGQLNGPNCTRLLTNMA 1350
Query: 7705 GDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAV 7884
G+ YA+A++P G+++W+ G + IE + + G R+++V +++ P +AV
Sbjct: 1351 GE-PYAIAVNPKRGMMYWTVVGDHS-------HIEEAAMDGTLRRILVQKNLQRPTGLAV 1402
Query: 7885 DFRNQKIYWADVNRLNIEVADYDGQNRKVIASGYRA----KSLDIWDRWLYMSDPLSNGV 8052
D+ +++IYWAD I YDG N V S + +DI++ ++Y + P NGV
Sbjct: 1403 DYFSERIYWADFELSIIGSVLYDGSNSVVSVSSKQGLLHPHRIDIFEDYIYGAGP-KNGV 1461
Query: 8053 FRIDKESGSGLE 8088
FR+ K +E
Sbjct: 1462 FRVQKFGHGSVE 1473
Score = 67.8 bits (164), Expect = 7e-09
Identities = 54/178 (30%), Positives = 72/178 (40%), Gaps = 13/178 (7%)
Frame = +1
Query: 664 KCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKL 843
KC N F C + RC + CD DC D DE C + C ++ C CI + +
Sbjct: 5 KCEENYFSCPSGRCILNTWICDGQKDCEDGRDEFHC-DSSCSWNQFAC-SAQKCISKHWI 62
Query: 844 CDGSKDCADGADEQQCSQNLCPSLGCQA---------GCHPSPH--GGECTCPSGYKLDD 990
CDG DC DG DE S ++C ++ C A C P GE CP G D+
Sbjct: 63 CDGEDDCGDGLDE---SDSICGAITCAADMFSCQGSRACVPRHWLCDGERDCPDG--SDE 117
Query: 991 RFHRTCSDINECAEFGYC--DQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGY 1158
C+ N C E + +++C + F C DC G G D GY
Sbjct: 118 LSTAGCAPNNTCDENAFMCHNKVCIPKQ--FVCDHDDDC-------GDGSDESPQCGY 166
Score = 47.8 bits (112), Expect = 0.008
Identities = 27/70 (38%), Positives = 35/70 (49%), Gaps = 8/70 (11%)
Frame = +1
Query: 3163 SSNSTQFQCKNGRCIPKEWKCDGENDCLDESDE--------IDEKGDKCFHETECAENTI 3318
S NS+ F CKNGRCIP CD ++DC D SDE + +K C + + +
Sbjct: 214 SCNSSFFMCKNGRCIPSGGLCDNKDDCGDGSDERNCHINECLSKKVSGCSQDCQDLPVSY 273
Query: 3319 KCRNTKKCIP 3348
KC KC P
Sbjct: 274 KC----KCWP 279
Score = 40.4 bits (93), Expect = 1.3
Identities = 39/148 (26%), Positives = 50/148 (33%), Gaps = 14/148 (9%)
Frame = +1
Query: 9544 QKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCMD 9723
Q KC F C SG CI + +CD DC D DE CS + QKC+
Sbjct: 1 QNKHKCEENYFSCPSGRCILNTWICDGQKDCEDGRDEFHC--DSSCSWNQFACSAQKCIS 58
Query: 9724 MK--IGYKCDCFEGF--------AID-ISDQKSCHNVNECYEGISGCSQKCDDKIGSYK- 9867
+ DC +G AI +D SC C C + D GS +
Sbjct: 59 KHWICDGEDDCGDGLDESDSICGAITCAADMFSCQGSRACVPRHWLCDGERDCPDGSDEL 118
Query: 9868 --CGCVDGYQLSSDDHSCKRTEMEPEPF 9945
GC + C P+ F
Sbjct: 119 STAGCAPNNTCDENAFMCHNKVCIPKQF 146
>gi|47229539|emb|CAG06735.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 2465
Score = 790 bits (2040), Expect = 0.0
Identities = 681/2552 (26%), Positives = 1062/2552 (40%), Gaps = 290/2552 (11%)
Frame = +1
Query: 661 KKCTANEFQCKNK-RCQPRKFRCDYYDDCGDNSDE--DECGEY---RCPPGKWNCPGTGH 822
K C+ +F CK+ C + +RCD DC D SDE D C RCPP ++ C GT
Sbjct: 14 KTCSPKQFVCKDGVTCISKGWRCDREKDCPDGSDEEPDVCPHSTVARCPPNEYRCGGTEV 73
Query: 823 CIDQLKLCDGSKDCADGADEQ-------------------QCSQNL------------CP 909
CI +LC+G DC DG DE CS+ C
Sbjct: 74 CIHMSRLCNGVPDCTDGWDEGPHCRGSAARAVHFPETFTLSCSEEAPLTGRRRELITNCS 133
Query: 910 SLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSC 1089
GCQ C +P G C C SGY++ + C D +EC+ +G C Q C N G+TCSC
Sbjct: 134 LRGCQESCGITPTGSACYCKSGYEIGPD-GKACKDFDECSVYGTCSQSCTNTNGGYTCSC 192
Query: 1090 LGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMK-LFVARREGLYRLNPKNPDEEVKKLAS 1266
+ P DN + + V D++ L +A + + + +
Sbjct: 193 VEGYL-------PQPDNRSCKAKNVP--VDRLPVLLIANSQNIQATSLSGTTVHSLLSTT 243
Query: 1267 GEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCL------ 1428
+ +DF Y + K+ W D + + +LKS R +
Sbjct: 244 TKQTTAMDFLYAEEKVCWIH-------VGDAPPSTHLKCARIPNLKSFTEERIINISLSL 296
Query: 1429 ------AVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFF 1590
AVDW+T Y ++ RI V +G+ LL L P IALDP G++FF
Sbjct: 297 HHVEQMAVDWLTGNFYFVDDVDDRIFVCDKNGQTCVTLLDQELYNPKGIALDPTVGKVFF 356
Query: 1591 TNQ---LKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGN 1761
T+ K+E MDG NR LV++ GI +D+ ++ VYW D +D +E +DY+G
Sbjct: 357 TDYGQIPKVERCDMDGQNRTKLVDSKIVFPHGITLDLVSRLVYWADAYLDYIEVVDYEGK 416
Query: 1762 DRRIVAQGMNVVPHPFGLALFDQYLYWTD------WTRLGVIQVEKFGSDTKLLWSNTEN 1923
+R + QG+ ++ H +GL +F+ YLY T+ + VI++ +F S + + +
Sbjct: 417 NRHTIIQGL-LIEHLYGLTVFENYLYATNSDNANMQPKTSVIKINRFNSTDYQVVTRVDK 475
Query: 1924 NVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYK---CA 2094
+ YH QP C +++ C +C+L G G+K C
Sbjct: 476 GG---ALHVYHQRRQPPVRSHAC---ELDQFGKAGGCSDICLL-------GNGHKTRTCR 522
Query: 2095 CPIGQKL-VNGKRCIDSIDYLLFSSNK----IVRGIFPEINEKALAEAVLPISPISQRRI 2259
C G L +GK C L K ++RG+ ++N K E ++PI + R
Sbjct: 523 CRSGFSLGSDGKSCKKPEHELFLVYGKGRPGVIRGM--DMNAKVPDEYMIPIENLMNPRA 580
Query: 2260 GMYFEVECDVHGNSFF--YADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWISKQL 2433
D H S F +AD I R + DG ++ + ++ DW++ L
Sbjct: 581 -------LDFHAESEFIYFADATSYIIGRQKIDGSERDTIVKEGIHIVEGIAVDWMADNL 633
Query: 2434 YYVDN-IRNSLEVVKIGETGLVHPDELVRRQLIT-ELRDPVSVVVHPWKGLLFYAE---- 2595
Y+ D+ + ++ V ++ + R+ LI ++ P ++VV P G +++ +
Sbjct: 634 YWTDDGPKKTISVARLEKASQT------RKTLIEGKITHPRAIVVDPLNGWMYWTDWEED 687
Query: 2596 --AMRPAAIYRCHIDGQNCQV-IRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDG 2766
+ I R +DG N + + + T+ P+ +++D + L W D I + +
Sbjct: 688 PKESKRGRIERAWMDGSNRNMFLSSKTVLWPNGLSLDVPQGILYWVDAFYDRIEMVYLNS 747
Query: 2767 KNVVKLDIDNPIPVAITIMN--EYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIF 2940
+ + A + + ++++ R SI ++ G V ++ IF
Sbjct: 748 SERKTVYEGQELIHAFGLCHYKHFLFWNEYRSGSIYKLDSTTG----TVTLLRSERPPIF 803
Query: 2941 SLKACSHQNQPIPDDSREHPCRASQ--CTQLCFATPSESHPNELEAKCACRQGFMINKEN 3114
++ Q Q + CR + C+ LC ATP +C C +++ N
Sbjct: 804 EIRMYDAQQQ-----QGSNACRVNNGGCSSLCLATPGGR-------QCGCADDQILDPAN 851
Query: 3115 NHSCQKDPAEKIEQLCSSNSTQFQCKNGRCIPKEWKCDGENDCLDESDEIDEKGDKCFHE 3294
N SC+ +P+ K C + +F CKN RCI + WKCDG+NDCLD SDE E H+
Sbjct: 852 NTSCKANPSYKPPPQCQAG--EFACKNSRCIQERWKCDGDNDCLDNSDEAPE----LCHQ 905
Query: 3295 TECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNHRC 3474
C + KC+N +CIP + C C ++ C + RC
Sbjct: 906 HTCPTDRFKCKN-NRCIPLRWLCDGDNDCGNDEDESNTTC---SARTCPPNQYSCASGRC 961
Query: 3475 IPEQWKXXXXXXXXXXXXEKLEMCGNATC-AANQFSCANGRCIPIYWLCDGDNDCYDGTD 3651
IP W E C TC QF+C NGRCI I W CD +
Sbjct: 962 IPISWTCDLDDDCGDRSDEPAS-CAYPTCFPLTQFTCNNGRCININWRCDNGESLLETLC 1020
Query: 3652 EDKERCPPVQCSA-----------LQFRCANGR------QCVPLRNHXXXXXXXXXXXXX 3780
R + SA F C+ CV L H
Sbjct: 1021 PPSVRLCNLHVSATISSSPLFVVFCAFLCSVALCCWFLFSCVVLFAHSAVFRWFCLSEKD 1080
Query: 3781 XXXAVTAESC----------TPDQFKCVSS----------GLCIPASWKXXXXXXXXXXS 3900
+C D+ C S G CIP W S
Sbjct: 1081 CGDGSDELNCPNPTDNDCGDNSDEAGCSHSCSSAQFKCNSGRCIPDYWTCDGDNDCGDYS 1140
Query: 3901 DEPKFGCTSGRQ-----CSSDQFKC----------------------------------- 3960
DE CT+ C +D+F+C
Sbjct: 1141 DETHANCTNQATRPPGGCHTDEFQCRMDSLCIPLRWRCDGDTDCMDLSDEKNCEGVTHMC 1200
Query: 3961 ---------GNGRCILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQE 4113
+ RCI W+CDG++DC D SDE + CK S HV C ND
Sbjct: 1201 DPAVKFGCRDSARCISKAWVCDGDSDCEDNSDEDNCDACKLS--------HHV-CANDST 1251
Query: 4114 TCIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCSFKCHNSP-NGPICSCPFGEQL- 4287
C+P +LC+G CP G+DE DLCS + CS C +P G ICSCP G +L
Sbjct: 1252 ICLPPEKLCNGADDCPDGSDEK---LCDLCSLENGDCSHNCTVAPGEGVICSCPLGMELG 1308
Query: 4288 VNKTKCEPENECLDSSSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVS 4467
N C+ ++ C CSQRC+ +K CSC EG+EL+ D CK D K I+ S
Sbjct: 1309 PNNKTCQIQSFCAKHLKCSQRCQQDKFSVKCSCYEGWELEPDMENCKSTDPFKPFIIF-S 1367
Query: 4468 NRNRIYYSDHKLDNWHTFGAIVENAIALAWDSLTDRIYWSDIREKKI----LSANRNGTN 4635
NR+ I D + + N IAL + +YW+D+ E KI LS N T+
Sbjct: 1368 NRHEIRRIDLNKGEFSVLVPGLRNTIALDFHLNQSALYWTDVVEDKIYRGKLSENGALTS 1427
Query: 4636 ATVFIADGLDITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIA 4815
V I GL EG+A+DW+ N+YWV+S+L+ IEVA L D RT L+ V PR IA
Sbjct: 1428 FDVVIQYGLATPEGLAVDWIAGNIYWVESNLDQIEVAKL-DGTMRTTLLAGEVEHPRAIA 1486
Query: 4816 VDPRKGVMFWTDWGQN-PCIERASMDGTDRQIIVKT--KIYWPNTIALDYTTDRVYFADS 4986
+DPR G++FWTDW + P IE ASM G R+ I K WPN + +DY R+ + D+
Sbjct: 1487 LDPRDGILFWTDWDASMPRIEAASMSGEGRKTIHKETGNGGWPNGLTVDYLERRILWIDA 1546
Query: 4987 KLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTS 5166
+ D I YDGSG +VL +++ HP A+ ++ +Y++D R L K+ G+
Sbjct: 1547 RSDAIYSAKYDGSGLIEVLRGHEYLSHPFAVTMYGGEVYWTDWRTNTLAKANKW-TGSNV 1605
Query: 5167 EYPSHTFSKALGVVAVHPVLQP----------------------------VIKNNPCST- 5259
T ++ + HP QP + NPC+
Sbjct: 1606 TVVQRTNTQPFDLQVYHPSRQPQGESHRLAGTSLKPHTIRLDCIILFVFAFLAPNPCAAK 1665
Query: 5260 ---NPCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNVFGIEMNSAS 5430
PCSHLCL+N TF+C CP KL + C + + FL+ ++ + G+++++
Sbjct: 1666 DGKKPCSHLCLINYNQTFSCACPHLMKLGPDRRNCY-EFRQFLLYARQIEIRGVDIDNPY 1724
Query: 5431 EKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNGG 5610
+++ VP + N YDAL ++ + + T + I R+ +NG
Sbjct: 1725 YNY--IISFTVP--DIDNVTVVDYDALEHRIY----------WSDVRTQT-IKRAFINGT 1769
Query: 5611 NKTKMFSSAVPDDAYCLGFDWNGRNL----VVGNKITQTIEIIRTQGKQYRSVILSNDQS 5778
+ S+ +P +A+ L DW RNL NK + I + R G +VI D+
Sbjct: 1770 GVETVVSADLP-NAHGLAVDWVSRNLFWTSYDANK--KQINVARLDGSFKNAVIQGLDKP 1826
Query: 5779 XXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAID 5958
G ++W D + A DGSN ++ +N + ++ID
Sbjct: 1827 HCLVLHPVL-------GKLYWTD------GDTINMANTDGSNRSILFTNQKGPVG-LSID 1872
Query: 5959 TTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLA------------------- 6081
+Y+ + I+ DG + G+ A
Sbjct: 1873 FDTEALYWISSGNSTINRCKLDGSGLEVLEGTKGKLTKATALAIMGGCGKKKRRVLSRIC 1932
Query: 6082 ------------FYGDRLFYADSAFDSIEVATINGDSQPPQWTHFKKDVENLANIKALQP 6225
G+ L++AD D I + W + + ++K
Sbjct: 1933 GTEAFAGWFILHLLGNTLWWADQGTDQIGTC---DKTDGGNWKVLRNSTSPMMHMKIYNE 1989
Query: 6226 RASSSGHPCHINNGNCDHICIPLMFAQRTCTCANGY-VKDGQTSCKLFDESFVIVATKTK 6402
+ C INNG+C +C+P R C C GY ++ GQ SC+ SF++ +
Sbjct: 1990 TVQEGTNLCSINNGDCSQLCLPTSPTTRACMCTAGYSLRTGQQSCEGVG-SFLLYSVHEG 2048
Query: 6403 VIGYPIDETQSKGVAMEPIGGLSI-TGVDYDYESKTIYVAE--ASGINKGITAYTIGESS 6573
+ G P+D + K A+ P+ G S+ G+D+ E+ TIY + S I++ T E
Sbjct: 2049 IRGIPLDPS-DKSDALVPVSGTSLAVGIDFHAENDTIYWVDMGLSTISRAKRDQTWRED- 2106
Query: 6574 PRAVIRDSIGSLTIKSLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPS 6753
V+ + IG ++ +A+DWI N+Y+ + + IEV++L+G++R ++++ + P
Sbjct: 2107 ---VVTNGIG--RVEGIAVDWIAGNIYWTDQGFD--VIEVARLNGSFRYVVISQGLDKPR 2159
Query: 6754 SIAVDPVSRYLYWADQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVD----------- 6900
+I V P YL+W + GQ P I+RS LDGS R V+V+ I+ P + +D
Sbjct: 2160 AITVHPERGYLFWTEWGQYPRIERSRLDGSERAVLVNVSISWPNGISIDYEVRQTGLFSH 2219
Query: 6901 --------------------VASKMIYWSDAKMDGIYRVR-STGGTPELV-RSDIASAAG 7014
V ++YW DA+ D I R+ TG E+V S+
Sbjct: 2220 SPPLFNGADGFASTVLLSVHVQENLLYWCDARTDKIERINLETGENREVVLASNNMDMFS 2279
Query: 7015 VALHGQNMYWTD-NRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRAS 7191
V++ +YW+D + SK N T + T + LKDI VF+ Q + +
Sbjct: 2280 VSVFESYIYWSDRTHANGSIKRGSKDNATDSVSLRTGIGVQLKDI---KVFNRARQ-QGT 2335
Query: 7192 SPCQITDNLRKSPCTQLCFATPGTQTPTCSCARGVL--KGRTCEEPDTYIMFSDGDKIID 7365
+ C++ + C QLC G TC+CA G+L G +C + D Y+++S+ +
Sbjct: 2336 NVCKVNN----GGCEQLCLFR-GNGQRTCACAHGMLAEDGCSCRDYDGYLLYSERTILKS 2390
Query: 7366 VAIEPDVKASRPLKDPFPEISNLQ-----TFD 7446
V + + + P+K PF + +++ TFD
Sbjct: 2391 VHLSDENNLNAPIK-PFEDPEHMKNVIALTFD 2421
Score = 509 bits (1311), Expect = e-142
Identities = 425/1620 (26%), Positives = 683/1620 (41%), Gaps = 100/1620 (6%)
Frame = +1
Query: 6310 TCTCANGYV-KDGQTSCKLFDESFVIVATKTKVIGYPIDETQSKGVAMEPIGGLSI---T 6477
TC+C GY+ + SCK + + I T G + + + T
Sbjct: 189 TCSCVEGYLPQPDNRSCKAKNVPVDRLPVLLIANSQNIQATSLSGTTVHSLLSTTTKQTT 248
Query: 6478 GVDYDY-ESKTIYV----AEASGINKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWIN 6642
+D+ Y E K ++ A S K + + +I S+ ++ +A+DW+
Sbjct: 249 AMDFLYAEEKVCWIHVGDAPPSTHLKCARIPNLKSFTEERIINISLSLHHVEQMAVDWLT 308
Query: 6643 YNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQ 6822
N YF++ +R I V +G LL + P IA+DP +++ D GQ P ++
Sbjct: 309 GNFYFVDDVDDR--IFVCDKNGQTCVTLLDQELYNPKGIALDPTVGKVFFTDYGQIPKVE 366
Query: 6823 RSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPELVRSD-- 6996
R +DG R +V S I P + +D+ S+++YW+DA +D I V G +
Sbjct: 367 RCDMDGQNRTKLVDSKIVFPHGITLDLVSRLVYWADAYLDYIEVVDYEGKNRHTIIQGLL 426
Query: 6997 IASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNN 7176
I G+ + +Y T++ + TS + V + G + V+
Sbjct: 427 IEHLYGLTVFENYLYATNSDNANMQPKTSVIKINRFNSTDYQVVTRVDKGGALHVYHQRR 486
Query: 7177 QPRASS-PCQITDNLRKSPCTQLCFATPGTQTPTCSCARGVL---KGRTCEEPD--TYIM 7338
QP S C++ + C+ +C G +T TC C G G++C++P+ +++
Sbjct: 487 QPPVRSHACELDQFGKAGGCSDICLLGNGHKTRTCRCRSGFSLGSDGKSCKKPEHELFLV 546
Query: 7339 FSDGDKIIDVAIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFS 7518
+ G + ++ + K P + N + D +YF + +
Sbjct: 547 YGKGRPGVIRGMDMNAKVPDEYMIPIENLMNPRALDFHAESEFIYFADATSYIIG----- 601
Query: 7519 MNNAENPRLVFGASKQPHAKEIRHISD-MKLDWLTQKIYFTTGRGGKVMAI---DTAGEH 7686
+ + G+ + KE HI + + +DW+ +Y+T K +++ + A +
Sbjct: 602 ------RQKIDGSERDTIVKEGIHIVEGIAVDWMADNLYWTDDGPKKTISVARLEKASQT 655
Query: 7687 LSTIASGDWTY--ALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESI 7860
T+ G T+ A+ +DP +G ++W+D RIER+ + G +R + +S
Sbjct: 656 RKTLIEGKITHPRAIVVDPLNGWMYWTDWEEDPKESK-RGRIERAWMDGSNRNMFLSSKT 714
Query: 7861 SL-PAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGYR---AKSLDIWDRWLYM 8028
L P +++D +YW D IE+ + RK + G A L + +L+
Sbjct: 715 VLWPNGLSLDVPQGILYWVDAFYDRIEMVYLNSSERKTVYEGQELIHAFGLCHYKHFLFW 774
Query: 8029 SDPLSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDN 8208
++ S ++++D +G+ + + S+R +R++ ++ + Q NA C+ +N
Sbjct: 775 NEYRSGSIYKLDSTTGT-VTLLRSERPPIFEIRMYDAQ-----QQQGSNA-----CRVNN 823
Query: 8209 GGCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSEPAKECLPPY 8388
GGC LC QC C D + L P
Sbjct: 824 GGCSSLCLATPGGR-------QCGCADD--------------------------QILDPA 850
Query: 8389 NFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHI 8568
N +C + NP+Y C C N RCI KC+
Sbjct: 851 N-----------NTSCKA----------NPSYKPPPQCQAGEFACKNSRCIQERWKCDGD 889
Query: 8569 DDCGDGSDEL-DCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPGL 8745
+DC D SDE + C F C N CI +CDG NDC +++ DES TC
Sbjct: 890 NDCLDNSDEAPELCHQHTCPTDRFKCKNNRCIPLRWLCDGDNDCGNDE--DESNTTCSAR 947
Query: 8746 PIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQ-HYVRCPSGRCI 8922
C + C + CI + CD DDCGD++DE C C C +GRCI
Sbjct: 948 T--CPPNQYSCASGR-CIPISWTCDLDDDCGDRSDE-PASCAYPTCFPLTQFTCNNGRCI 1003
Query: 8923 PETWQCDGDND------------CSDGWDETHTN-------CTDTAGKKICVGDYLFQCD 9045
W+CD C+ T ++ C +C +LF C
Sbjct: 1004 NINWRCDNGESLLETLCPPSVRLCNLHVSATISSSPLFVVFCAFLCSVALCCW-FLFSCV 1062
Query: 9046 NLKCISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTD-----QEFHCTSNAKLAQPKYE-- 9204
L S F + C N T D E C+ + AQ K
Sbjct: 1063 VLFAHSAVFRWFCLSEKDCGDGSDELN-CPNPTDNDCGDNSDEAGCSHSCSSAQFKCNSG 1121
Query: 9205 -CIPRAWLCDGDVTCAGGEDESTELCKTEKKE----CNKGEFRCS-NQHCIHSTWECDGD 9366
CIP W CDGD C DE+ C + C+ EF+C + CI W CDGD
Sbjct: 1122 RCIPDYWTCDGDNDCGDYSDETHANCTNQATRPPGGCHTDEFQCRMDSLCIPLRWRCDGD 1181
Query: 9367 NDCLDGSDEHANC--TYSSCQPDF-FQCANH-KCVPNSWKCDGNDDCEDGSDEKDCPKNS 9534
DC+D SDE NC C P F C + +C+ +W CDG+ DCED SDE +C
Sbjct: 1182 TDCMDLSDEK-NCEGVTHMCDPAVKFGCRDSARCISKAWVCDGDSDCEDNSDEDNCD--- 1237
Query: 9535 ASAQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQK 9714
A K S+ S C+ K+C+ DC D SDE LC D CSL E C
Sbjct: 1238 -----ACKLSHHVCANDSTICLPPEKLCNGADDCPDGSDEK-LC--DLCSL-ENGDCSHN 1288
Query: 9715 C-MDMKIGYKCDCFEGFAIDISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQ 9891
C + G C C G + + K+C + C + + CSQ+C S KC C +G++
Sbjct: 1289 CTVAPGEGVICSCPLGMELG-PNNKTCQIQSFCAKHLK-CSQRCQQDKFSVKCSCYEGWE 1346
Query: 9892 LSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAY 10071
L D +CK T+ +PF + +N+H IR+I ++ ++ + G N ++LD L + Y
Sbjct: 1347 LEPDMENCKSTDPF-KPFIIFSNRHEIRRIDLNKGEFSVLVPGLRNTIALDFHLNQSALY 1405
Query: 10072 LIDQGKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVC 10251
D + ++ R L E + L+S++ V+++ + EG+AVDW+ +Y + I V
Sbjct: 1406 WTDVVEDKIYRGKLSE-NGALTSFDVVIQYGLATPEGLAVDWIAGNIYWVESNLDQIEVA 1464
Query: 10252 ELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFFTEW-SLQPYIGRIALDGSPELQDPIFKL 10428
+LDG TL+ ++ P+AI + P G LF+T+W + P I ++ G E + I K
Sbjct: 1465 KLDGTMRTTLLAGEVEHPRAIALDPRDGILFWTDWDASMPRIEAASMSG--EGRKTIHKE 1522
Query: 10429 AEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHI--PAQRTSHVSSMVVFD 10602
+ GWPN + +DY R+ W DA + I +DG+G + + SH ++ ++
Sbjct: 1523 TGNG-GWPNGLTVDYLERRILWIDARSDAIYSAKYDGSGLIEVLRGHEYLSHPFAVTMYG 1581
Query: 10603 DYLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDLRIVHPMRQP-------------- 10740
+YW DW + + +KWTG N T++++T P DL++ HP RQP
Sbjct: 1582 GEVYWTDWRTNTLAKANKWTGSNVTVVQRTNTQPFDLQVYHPSRQPQGESHRLAGTSLKP 1641
Query: 10741 ---------------AYPNPCGDNNG--GCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTC 10869
PNPC +G CSHLCLI ++C+CP L D++ C
Sbjct: 1642 HTIRLDCIILFVFAFLAPNPCAAKDGKKPCSHLCLINY-NQTFSCACPHLMKLGPDRRNC 1700
Score = 330 bits (846), Expect = 6e-88
Identities = 342/1350 (25%), Positives = 512/1350 (37%), Gaps = 122/1350 (9%)
Frame = +1
Query: 9826 GCSQKCDDKIG--SYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDG-- 9993
GCS C G + C C G+ L SD SCK+ E E + IR + ++
Sbjct: 505 GCSDICLLGNGHKTRTCRCRSGFSLGSDGKSCKKPEHELFLVYGKGRPGVIRGMDMNAKV 564
Query: 9994 -NKYELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNVY 10170
++Y + + N +LD + Y D + R +D S +T+++ ++
Sbjct: 565 PDEYMIPIENLMNPRALDFHAESEFIYFADATSYIIGRQKIDG-----SERDTIVKEGIH 619
Query: 10171 GTEGIAVDWVGRKLYMLNR-QERSIRVCELD--GRFCKTLIRDRIQQPKAIVVHPGKGYL 10341
EGIAVDW+ LY + +++I V L+ + KTLI +I P+AIVV P G++
Sbjct: 620 IVEGIAVDWMADNLYWTDDGPKKTISVARLEKASQTRKTLIEGKITHPRAIVVDPLNGWM 679
Query: 10342 FFTEWSLQP------YIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDA 10503
++T+W P I R +DGS + L+ + WPN +++D L+W DA
Sbjct: 680 YWTDWEEDPKESKRGRIERAWMDGS----NRNMFLSSKTVLWPNGLSLDVPQGILYWVDA 735
Query: 10504 HLNEIGFMDFDGNGRRHI-PAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETI 10680
+ I + + + R+ + Q H + + +L+W ++ + + D TG T+
Sbjct: 736 FYDRIEMVYLNSSERKTVYEGQELIHAFGLCHYKHFLFWNEYRSGSIYKLDSTTG-TVTL 794
Query: 10681 LKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVL-LSD 10857
L+ ++R+ +Q N C NNGGCS LCL GG C C D +L ++
Sbjct: 795 LRSERPPIFEIRMYDAQQQQG-SNACRVNNGGCSSLCLATPGGR--QCGCADDQILDPAN 851
Query: 10858 QKTCE--------PNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRIC 11013
+C+ P C +FAC +++CI + W CDG+ DC D SDE E +C Q C
Sbjct: 852 NTSCKANPSYKPPPQCQAGEFAC--KNSRCIQERWKCDGDNDCLDNSDEAPE-LCHQHTC 908
Query: 11014 PVGEFQCTNHNCTRPFQIXXXXXXXXXXXXEQNCD---KACDPWMFKCAATGRCIPRRFT 11184
P F+C N+ C + E N + C P + C A+GRCIP +T
Sbjct: 909 PTDRFKCKNNRCIPLRWLCDGDNDCGNDEDESNTTCSARTCPPNQYSC-ASGRCIPISWT 967
Query: 11185 XXXXXXXXXRSDEADTLCMSAERNC-TAEEFRCNNNKCIAKAWRXXXXXX---------- 11331
RSDE A C +F CNN +CI WR
Sbjct: 968 CDLDDDCGDRSDEP---ASCAYPTCFPLTQFTCNNGRCININWRCDNGESLLETLCPPSV 1024
Query: 11332 ------XXXXXXETP--------ECAQIECKKGWTRCSSSYRCIPNWA-------FCNGQ 11448
+P C+ C C + C+ +A FC +
Sbjct: 1025 RLCNLHVSATISSSPLFVVFCAFLCSVALC------CWFLFSCVVLFAHSAVFRWFCLSE 1078
Query: 11449 DDCRDNSDEDKQRCPTCDDVG---------------EFRCATSGKCIPRRWMCDTENDCG 11583
DC D SDE PT +D G +F+C SG+CIP W CD +NDCG
Sbjct: 1079 KDCGDGSDELNCPNPTDNDCGDNSDEAGCSHSCSSAQFKC-NSGRCIPDYWTCDGDNDCG 1137
Query: 11584 DNSDELDASC-GGTTRP---CSESEFRCN-DGKCIPGSKVCDGTIQCSDGLDESQC--TL 11742
D SDE A+C TRP C EF+C D CIP CDG C D DE C
Sbjct: 1138 DYSDETHANCTNQATRPPGGCHTDEFQCRMDSLCIPLRWRCDGDTDCMDLSDEKNCEGVT 1197
Query: 11743 RRCLPGHR-QC-DDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFECANSVCI 11916
C P + C D CI++ CD DC + +DE +C+ C CAN
Sbjct: 1198 HMCDPAVKFGCRDSARCISKAWVCDGDSDCEDNSDEDNCD-----ACKLSHHVCAND--- 1249
Query: 11917 PRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDF 12096
S +CL +LCNG +DC D
Sbjct: 1250 --------------------------------------STICLPPEKLCNGADDC--PDG 1269
Query: 12097 SDEHL-SMCSSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTS 12273
SDE L +CS E GDCS
Sbjct: 1270 SDEKLCDLCS--LENGDCS----------------------------------------- 1286
Query: 12274 CEAFGNNGGCKHICTDV-RDGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTK 12450
H CT +G C C G P + K C CA + C+Q C K
Sbjct: 1287 -----------HNCTVAPGEGVICSCPLGMELGPNN-KTCQIQSFCAKHLKCSQRCQQDK 1334
Query: 12451 GSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGSGTNRHXXXXX 12630
S C C+E +E + ++C++ +I ++ + + N+
Sbjct: 1335 FSVKCSCYEGWELEPDM-----ENCKSTDPFKPFIIFSN----RHEIRRIDLNKGEFSVL 1385
Query: 12631 XXXXXXXXXXXXXPRKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTAI 12810
+ +YW D E IYR ++ DV P +
Sbjct: 1386 VPGLRNTIALDFHLNQSALYWTDVVEDKIYRGKLSENGAL---TSFDVVIQYGLATPEGL 1442
Query: 12811 AVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHL 12990
AVD+ GN++ V N++ I V DG ++AG +
Sbjct: 1443 AVDWIAGNIY--WVESNLDQ---------------------IEVAKLDGTMRTTLLAGEV 1479
Query: 12991 QQPTALITAPSAGRICYSD-AGLHAKIECADMDGTHRQIIVKDLVFS--PTSMAIDEGKG 13161
+ P A+ P G + ++D +IE A M G R+ I K+ P + +D +
Sbjct: 1480 EHPRAIALDPRDGILFWTDWDASMPRIEAASMSGEGRKTIHKETGNGGWPNGLTVDYLE- 1538
Query: 13162 NRIYWVDPKYRRVDAVNIDGSERTTVVHDRHI---PYAVDVFENHIYWLSRESKTLYVQD 13332
RI W+D + + + DGS V+ P+AV ++ +YW + TL +
Sbjct: 1539 RRILWIDARSDAIYSAKYDGSGLIEVLRGHEYLSHPFAVTMYGGEVYWTDWRTNTLAKAN 1598
Query: 13333 KFGRGRVSVLAS------DLEDGHTVRVSQKYAKDTQRT--------------------- 13431
K+ V+V+ DL+ H R Q + T
Sbjct: 1599 KWTGSNVTVVQRTNTQPFDLQVYHPSRQPQGESHRLAGTSLKPHTIRLDCIILFVFAFLA 1658
Query: 13432 ----VSGCERAQCSHLCVSLPSTGFACLCP 13509
+ + CSHLC+ + F+C CP
Sbjct: 1659 PNPCAAKDGKKPCSHLCLINYNQTFSCACP 1688
Score = 305 bits (780), Expect = 3e-80
Identities = 267/1036 (25%), Positives = 424/1036 (40%), Gaps = 96/1036 (9%)
Frame = +1
Query: 310 WHSVSCIAEYQR-------CDNITDCADGSDEKDCPASTVD--------------CSSQN 426
W SC+ + C + DC DGSDE +CP T + CSS
Sbjct: 1056 WFLFSCVVLFAHSAVFRWFCLSEKDCGDGSDELNCPNPTDNDCGDNSDEAGCSHSCSSAQ 1115
Query: 427 VFMCADGRQCFDVSKKCDGKYDCRDLSDEKDS-CSRNHT----ACFQYQFRCADKTQCIQ 591
F C GR C CDG DC D SDE + C+ T C +F+C + CI
Sbjct: 1116 -FKCNSGR-CIPDYWTCDGDNDCGDYSDETHANCTNQATRPPGGCHTDEFQCRMDSLCIP 1173
Query: 592 KSWVCDGSKDCADGSDEPDTCE--FKKCT-ANEFQCKNK-RCQPRKFRCDYYDDCGDNSD 759
W CDG DC D SDE + CE C A +F C++ RC + + CD DC DNSD
Sbjct: 1174 LRWRCDGDTDCMDLSDEKN-CEGVTHMCDPAVKFGCRDSARCISKAWVCDGDSDCEDNSD 1232
Query: 760 EDECGEYRCPPGKWNCPGTGH-CIDQLKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCH 936
ED C C C C+ KLC+G+ DC DG+DE+ C + C C
Sbjct: 1233 EDNCDA--CKLSHHVCANDSTICLPPEKLCNGADDCPDGSDEKLCDLCSLENGDCSHNCT 1290
Query: 937 PSPHGGE-CTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQ 1113
+P G C+CP G +L ++TC + CA+ C Q C + CSC
Sbjct: 1291 VAPGEGVICSCPLGMELGPN-NKTCQIQSFCAKHLKCSQRCQQDKFSVKCSCYEG----- 1344
Query: 1114 MEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDF 1293
E P +N C S + K + + R + R++ + V I +DF
Sbjct: 1345 WELEPDMEN------CKSTDPFKPFIIFSNRHEIRRIDLNKGEFSVLVPGLRNTI-ALDF 1397
Query: 1294 DYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESG 1473
++WTD + + + + G ++ + L P LAVDWI +Y +ES
Sbjct: 1398 HLNQSALYWTDVVEDKIYRGKLSENGALTSFDVVIQYGLATPEGLAVDWIAGNIYWVESN 1457
Query: 1474 SRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFT----NQLKLEAAAMDGTNRR 1641
+I+V+ DG RT LLA + P IALDP G +F+T + ++EAA+M G R+
Sbjct: 1458 LDQIEVAKLDGTMRTTLLAGEVEHPRAIALDPRDGILFWTDWDASMPRIEAASMSGEGRK 1517
Query: 1642 TL--VNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGL 1815
T+ + +G+ VD +R+ W+D + D + S Y G+ V +G + HPF +
Sbjct: 1518 TIHKETGNGGWPNGLTVDYLERRILWIDARSDAIYSAKYDGSGLIEVLRGHEYLSHPFAV 1577
Query: 1816 ALFDQYLYWTDWTRLGVIQVEKF-GSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQS-- 1986
++ +YWTDW + + K+ GS+ ++ N P + YHP QP G+S
Sbjct: 1578 TMYGGEVYWTDWRTNTLAKANKWTGSNVTVV---QRTNTQPFDLQVYHPSRQP-QGESHR 1633
Query: 1987 -------------ECL-----AMKIENPCTNAD----CEGMCILSKDNGGFGVGYKCACP 2100
+C+ A NPC D C +C+++ + + CACP
Sbjct: 1634 LAGTSLKPHTIRLDCIILFVFAFLAPNPCAAKDGKKPCSHLCLIN-----YNQTFSCACP 1688
Query: 2101 IGQKLVNGKR-CIDSIDYLLFSSNKIVRGIFPEINEKALAEAVLPISPISQRRIGMYFEV 2277
KL +R C + +LL++ +RG+ +I+ + P I V
Sbjct: 1689 HLMKLGPDRRNCYEFRQFLLYARQIEIRGV--DIDNPYYNYIISFTVP----DIDNVTVV 1742
Query: 2278 ECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDNIRN 2457
+ D + +++D+ TI R +G G V+ ++ DW+S+ L++ N
Sbjct: 1743 DYDALEHRIYWSDVRTQTIKRAFINGTGVETVVSADLPNAHGLAVDWVSRNLFWTSYDAN 1802
Query: 2458 SLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKGLLFYAEAMRPAAIYRCHIDG 2637
++ + D + +I L P +V+HP G L++ + I + DG
Sbjct: 1803 KKQI------NVARLDGSFKNAVIQGLDKPHCLVLHPVLGKLYWTDG---DTINMANTDG 1853
Query: 2638 QNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVKLD-----IDNPI 2802
N ++ G P ++IDF L W + TI+ DG + L+ +
Sbjct: 1854 SNRSILFTNQKG-PVGLSIDFDTEALYWISSGNSTINRCKLDGSGLEVLEGTKGKLTKAT 1912
Query: 2803 PVAIT---------------------------IMNEYIYYVHQRPYSIRRVHKKNGGGSK 2901
+AI ++ +++ Q I K +GG K
Sbjct: 1913 ALAIMGGCGKKKRRVLSRICGTEAFAGWFILHLLGNTLWWADQGTDQIGTCDKTDGGNWK 1972
Query: 2902 IVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCA 3081
++R S + N+ + + + C+QLC T + C
Sbjct: 1973 VLR------NSTSPMMHMKIYNETVQEGTNLCSINNGDCSQLCLPTSPTTR------ACM 2020
Query: 3082 CRQGFMINKENNHSCQ 3129
C G+ + + SC+
Sbjct: 2021 CTAGYSL-RTGQQSCE 2035
Score = 208 bits (529), Expect = 4e-51
Identities = 154/552 (27%), Positives = 249/552 (44%), Gaps = 25/552 (4%)
Frame = +1
Query: 9292 KECNKGEFRCSNQ-HCIHSTWECDGDNDCLDGSDEHAN-CTYSS---CQPDFFQCANHK- 9453
K C+ +F C + CI W CD + DC DGSDE + C +S+ C P+ ++C +
Sbjct: 14 KTCSPKQFVCKDGVTCISKGWRCDREKDCPDGSDEEPDVCPHSTVARCPPNEYRCGGTEV 73
Query: 9454 CVPNSWKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFD 9633
C+ S C+G DC DG DE P SA +A + + C ++A + R +
Sbjct: 74 CIHMSRLCNGVPDCTDGWDEG--PHCRGSAARAVHFP----ETFTLSCSEEAPLTGRRRE 127
Query: 9634 CTDRSDESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNECY 9813
I CSL C++ C G C C G+ I D K+C + +EC
Sbjct: 128 -----------LITNCSLRG---CQESCGITPTGSACYCKSGYEIG-PDGKACKDFDEC- 171
Query: 9814 EGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPE--PFFLLANKHYIRKISI 9987
CSQ C + G Y C CV+GY D+ SCK + + P L+AN I+ S+
Sbjct: 172 SVYGTCSQSCTNTNGGYTCSCVEGYLPQPDNRSCKAKNVPVDRLPVLLIANSQNIQATSL 231
Query: 9988 DGNK-YELAAQGFDNVVSLDIDLTEKKAYLIDQG----KLRLLRVDLDEMDSPLSSYETV 10152
G + L + ++D E+K I G L + + S
Sbjct: 232 SGTTVHSLLSTTTKQTTAMDFLYAEEKVCWIHVGDAPPSTHLKCARIPNLKSFTEERIIN 291
Query: 10153 LRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGK 10332
+ +++ E +AVDW+ Y ++ + I VC+ +G+ C TL+ + PK I + P
Sbjct: 292 ISLSLHHVEQMAVDWLTGNFYFVDDVDDRIFVCDKNGQTCVTLLDQELYNPKGIALDPTV 351
Query: 10333 GYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLN 10512
G +FFT++ P + R +DG KL + + +P+ I +D S ++W DA+L+
Sbjct: 352 GKVFFTDYGQIPKVERCDMDGQNRT-----KLVDSKIVFPHGITLDLVSRLVYWADAYLD 406
Query: 10513 EIGFMDFDGNGRRH-IPAQRTSHVSSMVVFDDYLYWADWN------LREVLRCDKWTGKN 10671
I +D++G R I H+ + VF++YLY + + V++ +++ +
Sbjct: 407 YIEVVDYEGKNRHTIIQGLLIEHLYGLTVFENYLYATNSDNANMQPKTSVIKINRFNSTD 466
Query: 10672 ETILKKTVQLPNDLRIVHPMRQPAYPNPCGD-----NNGGCSHLCLIGAGGNGYTCSCPD 10836
++ + V L + H RQP + + GGCS +CL+G G TC C
Sbjct: 467 YQVVTR-VDKGGALHVYHQRRQPPVRSHACELDQFGKAGGCSDICLLGNGHKTRTCRCRS 525
Query: 10837 QFVLLSDQKTCE 10872
F L SD K+C+
Sbjct: 526 GFSLGSDGKSCK 537
Score = 155 bits (393), Expect = 2e-35
Identities = 234/1143 (20%), Positives = 421/1143 (36%), Gaps = 135/1143 (11%)
Frame = +1
Query: 5266 CSHLCLLNNKNTFTCKCPMGEKLDASGKKC--IDDAKPFLVIIQKTNVFGIEMNSASEKE 5439
CS C +K + C C G +L+ + C D KPF++ + + I++N
Sbjct: 1326 CSQRCQ-QDKFSVKCSCYEGWELEPDMENCKSTDPFKPFIIFSNRHEIRRIDLNKGE--- 1381
Query: 5440 TPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNGGNKT 5619
+ +VP GL N + H N + + IYR ++
Sbjct: 1382 ---FSVLVP--GLRNTIALDF-----------HLNQSALYWTDVVEDKIYRGKLSENGAL 1425
Query: 5620 KMFSS------AVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVILSNDQSX 5781
F A P+ L DW N+ IE+ + G R+ +L+ +
Sbjct: 1426 TSFDVVIQYGLATPEG---LAVDWIAGNIYWVESNLDQIEVAKLDGTM-RTTLLAGEVEH 1481
Query: 5782 XXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAIDT 5961
G +FW D + A +G + + + + + +D
Sbjct: 1482 PRAIALDPRD-----GILFWTDWDASMPRIEAASMSGEGRKTIHKETGNGGWPNGLTVDY 1536
Query: 5962 TNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGG--RQPNGLAFYGDRLFYADSAFDSIEV 6135
R+ + +A++ I S YDG VL P + YG +++ D +++
Sbjct: 1537 LERRILWIDARSDAIYSAKYDGSGLIEVLRGHEYLSHPFAVTMYGGEVYWTDWRTNTLAK 1596
Query: 6136 ATINGDSQPPQWTHFKKDVENLANIKAL---------QPRASS----------------- 6237
A +WT V N + QP+ S
Sbjct: 1597 AN--------KWTGSNVTVVQRTNTQPFDLQVYHPSRQPQGESHRLAGTSLKPHTIRLDC 1648
Query: 6238 ---------SGHPCHINNGN--CDHICIPLMFAQRTCTCANGYVKDGQTSCKLFD-ESFV 6381
+ +PC +G C H+C+ +C C + +K G ++ F+
Sbjct: 1649 IILFVFAFLAPNPCAAKDGKKPCSHLCLINYNQTFSCACPH-LMKLGPDRRNCYEFRQFL 1707
Query: 6382 IVATKTKVIGYPIDETQSKGVAMEPIGGL-SITGVDYDYESKTIYVAEASGINKGITAYT 6558
+ A + ++ G ID + + + ++T VDYD IY ++ + I
Sbjct: 1708 LYARQIEIRGVDIDNPYYNYIISFTVPDIDNVTVVDYDALEHRIYWSDVR--TQTIKRAF 1765
Query: 6559 IGESSPRAVIRDSIGSLTIKSLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTK 6738
I + V+ + + LA+DW++ N+++ ++DA + I V++LDG+++ ++
Sbjct: 1766 INGTGVETVVSADLPNA--HGLAVDWVSRNLFWTSYDANKKQINVARLDGSFKNAVIQG- 1822
Query: 6739 TETPSSIAVDPVSRYLYWADQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMI 6918
+ P + + PV LYW D TI + DGS R ++ ++ P L +D ++ +
Sbjct: 1823 LDKPHCLVLHPVLGKLYWTDGD---TINMANTDGSNRSILFTNQKG-PVGLSIDFDTEAL 1878
Query: 6919 YWSDAKMDGIYRVRSTGGTPELV---RSDIASAAGVA----------------------- 7020
YW + I R + G E++ + + A +A
Sbjct: 1879 YWISSGNSTINRCKLDGSGLEVLEGTKGKLTKATALAIMGGCGKKKRRVLSRICGTEAFA 1938
Query: 7021 ------LHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQP 7182
L G ++W D +++ +L +T I + V N
Sbjct: 1939 GWFILHLLGNTLWWADQGTDQIGTCDKTDGGNWKVLRNSTSPMMHMKIYNETVQEGTNL- 1997
Query: 7183 RASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCARGV---LKGRTCEEPDTYIMFSDGD 7353
C I + C+QLC T T T C C G ++CE +++++S +
Sbjct: 1998 -----CSINNG----DCSQLCLPTSPT-TRACMCTAGYSLRTGQQSCEGVGSFLLYSVHE 2047
Query: 7354 KIIDVAIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAE 7533
I + ++P K+ + P S D +Y+V ++ +++ A+
Sbjct: 2048 GIRGIPLDPSDKSDALV--PVSGTSLAVGIDFHAENDTIYWV-------DMGLSTISRAK 2098
Query: 7534 NPRLVFGASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTIASG-- 7707
+ + I + + +DW+ IY+T + G + S
Sbjct: 2099 RDQTW---REDVVTNGIGRVEGIAVDWIAGNIYWTDQGFDVIEVARLNGSFRYVVISQGL 2155
Query: 7708 DWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVD 7887
D A+ + P G LFW++ G PRIERS L G R V+V+ SIS P I++D
Sbjct: 2156 DKPRAITVHPERGYLFWTEWGQY-------PRIERSRLDGSERAVLVNVSISWPNGISID 2208
Query: 7888 F-------------------------------RNQKIYWAD-----VNRLNIEVADYDGQ 7959
+ + +YW D + R+N+E G+
Sbjct: 2209 YEVRQTGLFSHSPPLFNGADGFASTVLLSVHVQENLLYWCDARTDKIERINLET----GE 2264
Query: 7960 NRKVIASGYRAK--SLDIWDRWLYMSDPL-SNGVFRIDKESGSGLENVVSDRRIPGA--- 8121
NR+V+ + S+ +++ ++Y SD +NG I + S + VS R G
Sbjct: 2265 NREVVLASNNMDMFSVSVFESYIYWSDRTHANG--SIKRGSKDNATDSVSLRTGIGVQLK 2322
Query: 8122 -LRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLCTVVADDIGLAA------SKVQCS 8280
++VF R R Q N +CK +NGGC+QLC + A ++ CS
Sbjct: 2323 DIKVFN-----RARQQGTN-----VCKVNNGGCEQLCLFRGNGQRTCACAHGMLAEDGCS 2372
Query: 8281 CND 8289
C D
Sbjct: 2373 CRD 2375
Score = 141 bits (356), Expect = 4e-31
Identities = 171/754 (22%), Positives = 298/754 (38%), Gaps = 77/754 (10%)
Frame = +1
Query: 6271 CDHICIPLMFAQRTCTCANGY-VKDGQTSCKLFD--ESFVIVATKTKVIGYPIDETQSKG 6441
C C F+ + C+C G+ ++ +CK D + F+I + + ++ ++ KG
Sbjct: 1326 CSQRCQQDKFSVK-CSCYEGWELEPDMENCKSTDPFKPFIIFSNRHEIRRIDLN----KG 1380
Query: 6442 VAMEPIGGLSIT-GVDYDYESKTIYVAEA--SGINKGITAYTIGESSPRAVIRDSIGSLT 6612
+ GL T +D+ +Y + I +G + +S VI+ G T
Sbjct: 1381 EFSVLVPGLRNTIALDFHLNQSALYWTDVVEDKIYRGKLSENGALTSFDVVIQ--YGLAT 1438
Query: 6613 IKSLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYW 6792
+ LA+DWI N+Y++ + ++ IEV+KLDGT R LL + E P +IA+DP L+W
Sbjct: 1439 PEGLAVDWIAGNIYWVESNLDQ--IEVAKLDGTMRTTLLAGEVEHPRAIALDPRDGILFW 1496
Query: 6793 AD-QGQKPTIQRSFLDGSRREVI--VSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRS 6963
D P I+ + + G R+ I + P L VD + I W DA+ D IY +
Sbjct: 1497 TDWDASMPRIEAASMSGEGRKTIHKETGNGGWPNGLTVDYLERRILWIDARSDAIYSAKY 1556
Query: 6964 TG-GTPELVRSD--IASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAAS 7134
G G E++R ++ V ++G +YWTD R L +A ++ T
Sbjct: 1557 DGSGLIEVLRGHEYLSHPFAVTMYGGEVYWTDWRTNTLAKANKWTGSNVTVVQRTNTQPF 1616
Query: 7135 LKDIGDVAVFSSNNQPRASS-----------------------------PCQITDNLRKS 7227
D+ V+ + QP+ S PC D K
Sbjct: 1617 -----DLQVYHPSRQPQGESHRLAGTSLKPHTIRLDCIILFVFAFLAPNPCAAKDG--KK 1669
Query: 7228 PCTQLCFATPGTQTPTCSCARGVLKG---RTCEEPDTYIMFSDGDKIIDVAIEPDVKASR 7398
PC+ LC QT +C+C + G R C E +++++ +I V I+ + +
Sbjct: 1670 PCSHLCLINYN-QTFSCACPHLMKLGPDRRNCYEFRQFLLYARQIEIRGVDID-NPYYNY 1727
Query: 7399 PLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAENPRLVFGASKQPHAK 7578
+ P+I N+ D D R+Y+ S V + N V A
Sbjct: 1728 IISFTVPDIDNVTVVDYDALEHRIYW---SDVRTQTIKRAFINGTGVETVVSA------- 1777
Query: 7579 EIRHISDMKLDWLTQKIYFTTGRGGK----VMAIDTAGEHLSTIASG-DWTYALAIDPCS 7743
++ + + +DW+++ +++T+ K V +D G + + G D + L + P
Sbjct: 1778 DLPNAHGLAVDWVSRNLFWTSYDANKKQINVARLD--GSFKNAVIQGLDKPHCLVLHPVL 1835
Query: 7744 GLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVDFRNQKIYWADVN 7923
G L+W+D I +N G +R ++ + P +++DF + +YW
Sbjct: 1836 GKLYWTDGD----------TINMANTDGSNRSILFTNQKG-PVGLSIDFDTEALYWISSG 1884
Query: 7924 RLNIEVADYDGQNRKV---------------IASGYRAKSLDIWDR---------WLYMS 8031
I DG +V I G K + R W ++
Sbjct: 1885 NSTINRCKLDGSGLEVLEGTKGKLTKATALAIMGGCGKKKRRVLSRICGTEAFAGW-FIL 1943
Query: 8032 DPLSNGVFRIDKESGSGLENV-VSDRRIPGALRVFASESDVRTRNQVCNALTSQ---LCK 8199
L N ++ D+ G + + D+ G +V + + ++ N + LC
Sbjct: 1944 HLLGNTLWWADQ----GTDQIGTCDKTDGGNWKVLRNSTSPMMHMKIYNETVQEGTNLCS 1999
Query: 8200 TDNGGCDQLCTVVADDIGLAASKVQCSCNDTYEL 8301
+NG C QLC + + + C C Y L
Sbjct: 2000 INNGDCSQLC------LPTSPTTRACMCTAGYSL 2027
Score = 139 bits (350), Expect = 2e-30
Identities = 123/494 (24%), Positives = 200/494 (39%), Gaps = 13/494 (2%)
Frame = +1
Query: 11851 CEDVSRRTCSPFEFECANSV-CIPRKFMXXXXXXXXXXSDETSSECRS---AQCDPPLRF 12018
C + +TCSP +F C + V CI + + SDE C A+C PP +
Sbjct: 8 CFSSAPKTCSPKQFVCKDGVTCISKGWRCDREKDCPDGSDEEPDVCPHSTVARC-PPNEY 66
Query: 12019 RCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSFSEYGDCSSDQFKCANGKCVNGTV 12198
RC + +C+++ +LCNG DC + E C + + T+
Sbjct: 67 RCGGTEVCIHMSRLCNGVPDC------------TDGWDEGPHCRGSAARAVHFP-ETFTL 113
Query: 12199 ACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQS 12378
+C + E+ T+C GC+ C G C+C+ G+ P
Sbjct: 114 SCSEEAPLTGRRREL-------ITNCSL----RGCQESCGITPTGSACYCKSGYEIGPDG 162
Query: 12379 PKECIDIDECAGNNTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKG---DAAN 12549
K C D DEC+ TC+Q C NT G Y C C E Y + + C+AK D
Sbjct: 163 -KACKDFDECSVYGTCSQSCTNTNGGYTCSCVEGY-----LPQPDNRSCKAKNVPVDRLP 216
Query: 12550 VMIGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWI---DGSERTIY 12720
V++ A+ +Q + SGT H +E + WI D T
Sbjct: 217 VLLIANSQNIQ-ATSLSGTTVHSLLSTTTKQTTAMDFLYA--EEKVCWIHVGDAPPSTHL 273
Query: 12721 RSA-IANGNQSHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAVSENIENGLVTARKKR 12897
+ A I N E + +++ + V +AVD+ TGN +
Sbjct: 274 KCARIPNLKSFTEERIINISLSLHHV--EQMAVDWLTGNFYFV----------------- 314
Query: 12898 MSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECA 13077
+ +D++ IFVC +G+ ++ L P + P+ G++ ++D G K+E
Sbjct: 315 --DDVDDR----IFVCDKNGQTCVTLLDQELYNPKGIALDPTVGKVFFTDYGQIPKVERC 368
Query: 13078 DMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHI 13257
DMDG +R +V + P + +D +YW D ++ V+ +G R T++ I
Sbjct: 369 DMDGQNRTKLVDSKIVFPHGITLDL-VSRLVYWADAYLDYIEVVDYEGKNRHTIIQGLLI 427
Query: 13258 P--YAVDVFENHIY 13293
Y + VFEN++Y
Sbjct: 428 EHLYGLTVFENYLY 441
Score = 134 bits (338), Expect = 5e-29
Identities = 112/383 (29%), Positives = 162/383 (42%), Gaps = 40/383 (10%)
Frame = +1
Query: 9802 NECYEGISGCSQKCDDKIGSYK-CGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHY-IR 9975
N C CSQ C + + C C GY L + SC E FLL + H IR
Sbjct: 1996 NLCSINNGDCSQLCLPTSPTTRACMCTAGYSLRTGQQSC-----EGVGSFLLYSVHEGIR 2050
Query: 9976 KISIDGNKYELA---AQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYE 10146
I +D + A G V +D Y +D G + R D+ + E
Sbjct: 2051 GIPLDPSDKSDALVPVSGTSLAVGIDFHAENDTIYWVDMGLSTISRAKRDQ-----TWRE 2105
Query: 10147 TVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHP 10326
V+ + + EGIAVDW+ +Y ++ I V L+G F +I + +P+AI VHP
Sbjct: 2106 DVVTNGIGRVEGIAVDWIAGNIYWTDQGFDVIEVARLNGSFRYVVISQGLDKPRAITVHP 2165
Query: 10327 GKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDY-------FS-- 10479
+GYLF+TEW P I R LDGS L + WPN I+IDY FS
Sbjct: 2166 ERGYLFWTEWGQYPRIERSRLDGSERA-----VLVNVSISWPNGISIDYEVRQTGLFSHS 2220
Query: 10480 ----------------------DRLFWGDAHLNEIGFMDFD-GNGRRHIPAQRTSHVSSM 10590
+ L+W DA ++I ++ + G R + A + S+
Sbjct: 2221 PPLFNGADGFASTVLLSVHVQENLLYWCDARTDKIERINLETGENREVVLASNNMDMFSV 2280
Query: 10591 VVFDDYLYWADWNLR--EVLRCDKWTGKNETILKKTVQLP-NDLRIVHPMRQPAYPNPCG 10761
VF+ Y+YW+D + R K + L+ + + D+++ + RQ N C
Sbjct: 2281 SVFESYIYWSDRTHANGSIKRGSKDNATDSVSLRTGIGVQLKDIKVFNRARQQG-TNVCK 2339
Query: 10762 DNNGGCSHLCLIGAGGNGYTCSC 10830
NNGGC LCL G TC+C
Sbjct: 2340 VNNGGCEQLCLFRGNGQ-RTCAC 2361
Score = 113 bits (282), Expect = 2e-22
Identities = 99/375 (26%), Positives = 137/375 (36%), Gaps = 49/375 (13%)
Frame = +1
Query: 85 IQVDSPPSVRSRIISASVNTASSVCNENDFRCNDGKCIRT----------EWXXXXXXXX 234
++ + PP R+ A S+ C N+ C+ C+ T +
Sbjct: 795 LRSERPPIFEIRMYDAQQQQGSNACRVNNGGCSS-LCLATPGGRQCGCADDQILDPANNT 853
Query: 235 XXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDC 414
P P C++ ++ C + CI E +CD DC D SDE C
Sbjct: 854 SCKANPSYKPPPQCQAGEFACK-----NSRCIQERWKCDGDNDCLDNSDEAPELCHQHTC 908
Query: 415 SSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQK 594
+ F C + R C + CDG DC + DE ++ T C Q+ CA +CI
Sbjct: 909 PTDR-FKCKNNR-CIPLRWLCDGDNDCGNDEDESNTTCSART-CPPNQYSCA-SGRCIPI 964
Query: 595 SWVCDGSKDCADGSDEPDTCEFKKC-TANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDEC 771
SW CD DC D SDEP +C + C +F C N RC +RCD + +
Sbjct: 965 SWTCDLDDDCGDRSDEPASCAYPTCFPLTQFTCNNGRCININWRCD---------NGESL 1015
Query: 772 GEYRCPPGKWNC----PGT-------------------------------GHCIDQLKLC 846
E CPP C T H C
Sbjct: 1016 LETLCPPSVRLCNLHVSATISSSPLFVVFCAFLCSVALCCWFLFSCVVLFAHSAVFRWFC 1075
Query: 847 DGSKDCADGADEQQC---SQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDI 1017
KDC DG+DE C + N C +AGC S + C SG + D + TC
Sbjct: 1076 LSEKDCGDGSDELNCPNPTDNDCGDNSDEAGCSHSCSSAQFKCNSGRCIPD--YWTCDGD 1133
Query: 1018 NECAEFGYCDQLCAN 1062
N+C + Y D+ AN
Sbjct: 1134 NDCGD--YSDETHAN 1146
Score = 108 bits (271), Expect = 3e-21
Identities = 79/261 (30%), Positives = 101/261 (38%), Gaps = 38/261 (14%)
Frame = +1
Query: 148 SSVCNENDFRCNDGKCIRTEWX--------XXXXXXXXXXXXXXXXPHPGCKSDQWQCDT 303
S C+ F+CN G+CI W P GC +D++QC
Sbjct: 1108 SHSCSSAQFKCNSGRCIPDYWTCDGDNDCGDYSDETHANCTNQATRPPGGCHTDEFQCRM 1167
Query: 304 YTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDG 483
CI RCD TDC D SDEK+C T C F C D +C + CDG
Sbjct: 1168 ----DSLCIPLRWRCDGDTDCMDLSDEKNCEGVTHMCDPAVKFGCRDSARCISKAWVCDG 1223
Query: 484 KYDCRDLSDEK--DSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEP--DT 651
DC D SDE D+C +H C D T C+ +C+G+ DC DGSDE D
Sbjct: 1224 DSDCEDNSDEDNCDACKLSHHVC------ANDSTICLPPEKLCNGADDCPDGSDEKLCDL 1277
Query: 652 CEFKK--CTAN-----------------EFQCKNKRCQPRKFRCDYYDDCGDNSDEDE-- 768
C + C+ N E NK CQ + F C + C +D+
Sbjct: 1278 CSLENGDCSHNCTVAPGEGVICSCPLGMELGPNNKTCQIQSF-CAKHLKCSQRCQQDKFS 1336
Query: 769 ----CGE-YRCPPGKWNCPGT 816
C E + P NC T
Sbjct: 1337 VKCSCYEGWELEPDMENCKST 1357
Score = 102 bits (253), Expect = 4e-19
Identities = 102/430 (23%), Positives = 169/430 (38%), Gaps = 45/430 (10%)
Frame = +1
Query: 1222 LNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSL 1401
L+P + + + ++ GIDF + I+W D + A D + +
Sbjct: 2054 LDPSDKSDALVPVSGTSLAVGIDFHAENDTIYWVDMGLSTISRAKRDQTWR----EDVVT 2109
Query: 1402 KSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGE 1581
+ +AVDWI +Y + G I+V+ +G R V+++ GL P I + P RG
Sbjct: 2110 NGIGRVEGIAVDWIAGNIYWTDQGFDVIEVARLNGSFRYVVISQGLDKPRAITVHPERGY 2169
Query: 1582 MFFTN---QLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKR---------------- 1704
+F+T ++E + +DG+ R LVN +GI +D ++
Sbjct: 2170 LFWTEWGQYPRIERSRLDGSERAVLVNVSISWPNGISIDYEVRQTGLFSHSPPLFNGADG 2229
Query: 1705 ---------------VYWVDPKVDRLESIDYQ-GNDRRIVAQGMNVVPHPFGLALFDQYL 1836
+YW D + D++E I+ + G +R +V N+ F +++F+ Y+
Sbjct: 2230 FASTVLLSVHVQENLLYWCDARTDKIERINLETGENREVVLASNNM--DMFSVSVFESYI 2287
Query: 1837 YWTDWTRL-GVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIEN 2013
YW+D T G I+ + T + T V I ++ Q G N
Sbjct: 2288 YWSDRTHANGSIKRGSKDNATDSVSLRTGIGVQLKDIKVFNRARQQGT-----------N 2336
Query: 2014 PC--TNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGKRCIDSIDYLLFSSNKIVRGI 2187
C N CE +C+ + NG CAC G +G C D YLL+S I++ +
Sbjct: 2337 VCKVNNGGCEQLCLF-RGNGQ----RTCACAHGMLAEDGCSCRDYDGYLLYSERTILKSV 2391
Query: 2188 FPEINEKALAEAVLPISPISQ-RRIGMYFEVECDVHG------NSFFYADIMDNTIYRIR 2346
A PI P + + D G N F++DI I +I
Sbjct: 2392 HLSDENNLNA----PIKPFEDPEHMKNVIALTFDYRGGGGKGANRVFFSDIHFGNIQQIS 2447
Query: 2347 PDGEGAAPVL 2376
DG V+
Sbjct: 2448 DDGSDRKTVV 2457
Score = 102 bits (253), Expect = 4e-19
Identities = 62/173 (35%), Positives = 80/173 (45%), Gaps = 3/173 (1%)
Frame = +1
Query: 349 DNITDCADGSDEKDCPASTVDCSSQ-NVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSC 525
D I D A+ + K P+ Q F C + R C KCDG DC D SDE
Sbjct: 844 DQILDPANNTSCKANPSYKPPPQCQAGEFACKNSR-CIQERWKCDGDNDCLDNSDEAPEL 902
Query: 526 SRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDT-CEFKKCTANEFQCKNKR 702
HT C +F+C + +CI W+CDG DC + DE +T C + C N++ C + R
Sbjct: 903 CHQHT-CPTDRFKCKNN-RCIPLRWLCDGDNDCGNDEDESNTTCSARTCPPNQYSCASGR 960
Query: 703 CQPRKFRCDYYDDCGDNSDED-ECGEYRCPPGKWNCPGTGHCIDQLKLCDGSK 858
C P + CD DDCGD SDE C C P G CI+ CD +
Sbjct: 961 CIPISWTCDLDDDCGDRSDEPASCAYPTCFPLTQFTCNNGRCININWRCDNGE 1013
Score = 98.6 bits (244), Expect = 4e-18
Identities = 95/391 (24%), Positives = 154/391 (39%), Gaps = 38/391 (9%)
Frame = +1
Query: 9814 EGISGCSQKCDDKIG-SYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISID 9990
+G CS C ++ C C +L D +C E F L A + IR + ID
Sbjct: 1666 DGKKPCSHLCLINYNQTFSCACPHLMKLGPDRRNC----YEFRQFLLYARQIEIRGVDID 1721
Query: 9991 GNKYE----LAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLR 10158
Y DNV +D D E + Y D + R ++ + ETV+
Sbjct: 1722 NPYYNYIISFTVPDIDNVTVVDYDALEHRIYWSDVRTQTIKRAFING-----TGVETVVS 1776
Query: 10159 HNVYGTEGIAVDWVGRKLY--MLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGK 10332
++ G+AVDWV R L+ + ++ I V LDG F K + + +P +V+HP
Sbjct: 1777 ADLPNAHGLAVDWVSRNLFWTSYDANKKQINVARLDGSF-KNAVIQGLDKPHCLVLHPVL 1835
Query: 10333 GYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLN 10512
G L++T+ I DGS + + P ++ID+ ++ L+W + +
Sbjct: 1836 GKLYWTDGDT---INMANTDGSNR------SILFTNQKGPVGLSIDFDTEALYWISSGNS 1886
Query: 10513 EIGFMDFDGNGRRHIP------------------AQRTSHVSSMV-------------VF 10599
I DG+G + ++ V S + +
Sbjct: 1887 TINRCKLDGSGLEVLEGTKGKLTKATALAIMGGCGKKKRRVLSRICGTEAFAGWFILHLL 1946
Query: 10600 DDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGC 10779
+ L+WAD ++ CDK G N +L+ + ++I + Q N C NNG C
Sbjct: 1947 GNTLWWADQGTDQIGTCDKTDGGNWKVLRNSTSPMMHMKIYNETVQEG-TNLCSINNGDC 2005
Query: 10780 SHLCLIGAGGNGYTCSCPDQFVLLSDQKTCE 10872
S LCL C C + L + Q++CE
Sbjct: 2006 SQLCL-PTSPTTRACMCTAGYSLRTGQQSCE 2035
Score = 80.1 bits (196), Expect = 1e-12
Identities = 103/478 (21%), Positives = 182/478 (37%), Gaps = 24/478 (5%)
Frame = +1
Query: 12310 ICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKG--SYLCRCHEDY 12483
+ T V G H R P C ++D+ C+ +CL G + CRC +
Sbjct: 469 VVTRVDKGGALHVYHQRRQPPVRSHAC-ELDQFGKAGGCSDICLLGNGHKTRTCRCRSGF 527
Query: 12484 ENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXX 12663
+GS GK C+ ++ G V + +
Sbjct: 528 S----LGS-DGKSCKKPEHELFLVYGKGRPGVIRGMDMNAKVPDEYMIPIENLMNPRALD 582
Query: 12664 XXPRKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFI 12843
E +Y+ D + I G Q +G + D + IAVD+ NL+
Sbjct: 583 FHAESEFIYFADATSYII-------GRQKIDGSERDTIVKEGIHIVEGIAVDWMADNLYW 635
Query: 12844 AAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPS 13023
+ + + AR ++ S+ K ++ G + P A++ P
Sbjct: 636 T--DDGPKKTISVARLEKASQT------------------RKTLIEGKITHPRAIVVDPL 675
Query: 13024 AGRICYSD------AGLHAKIECADMDGTHRQIIVKD-LVFSPTSMAIDEGKGNRIYWVD 13182
G + ++D +IE A MDG++R + + V P +++D +G +YWVD
Sbjct: 676 NGWMYWTDWEEDPKESKRGRIERAWMDGSNRNMFLSSKTVLWPNGLSLDVPQGI-LYWVD 734
Query: 13183 PKYRRVDAVNIDGSERTTVVHDRHIPYAVDV--FENHIYWLSRESKTLYVQDKFGRGRVS 13356
Y R++ V ++ SER TV + + +A + +++ ++W S ++Y D G V+
Sbjct: 735 AFYDRIEMVYLNSSERKTVYEGQELIHAFGLCHYKHFLFWNEYRSGSIYKLDS-TTGTVT 793
Query: 13357 VLASDLEDGHTVRVSQKYAKDTQRTVSGC--ERAQCSHLCVSLPSTGFACLCPDGIVPQL 13530
+L S+ +R+ Y Q+ + C CS LC++ P G C C D +
Sbjct: 794 LLRSERPPIFEIRM---YDAQQQQGSNACRVNNGGCSSLCLATPG-GRQCGCADDQILDP 849
Query: 13531 DGSCATQHVEALTMPKQCK-----CTNG------GKCRLDGSCECTSDFEGDQCEKES 13671
+ + + + P QC+ C N KC D C SD + C + +
Sbjct: 850 ANNTSCKANPSYKPPPQCQAGEFACKNSRCIQERWKCDGDNDCLDNSDEAPELCHQHT 907
Score = 63.5 bits (153), Expect = 1e-07
Identities = 81/413 (19%), Positives = 153/413 (36%), Gaps = 37/413 (8%)
Frame = +1
Query: 12415 NNTCTQLCLNTKGSY-LCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSL 12591
N C+QLCL T + C C Y TG+ +G + ++ + + + L
Sbjct: 2002 NGDCSQLCLPTSPTTRACMCTAGYSLR------TGQQS-CEGVGSFLLYSVHEGIRGIPL 2054
Query: 12592 HGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERTIYRSAIANGNQSHEGQKLD 12771
S ++ + +YW+D TI R+ + + + D
Sbjct: 2055 DPS--DKSDALVPVSGTSLAVGIDFHAENDTIYWVDMGLSTISRA------KRDQTWRED 2106
Query: 12772 VDFAAMGVVPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLP 12951
V +G V IAVD+ GN++ +Q I V
Sbjct: 2107 VVTNGIGRVE-GIAVDWIAGNIYWT-----------------------DQGFDVIEVARL 2142
Query: 12952 DGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSP 13131
+G + +++ L +P A+ P G + +++ G + +IE + +DG+ R ++V + P
Sbjct: 2143 NGSFRYVVISQGLDKPRAITVHPERGYLFWTEWGQYPRIERSRLDGSERAVLVNVSISWP 2202
Query: 13132 TSMAID------------------------------EGKGNRIYWVDPKYRRVDAVNID- 13218
++ID + N +YW D + +++ +N++
Sbjct: 2203 NGISIDYEVRQTGLFSHSPPLFNGADGFASTVLLSVHVQENLLYWCDARTDKIERINLET 2262
Query: 13219 GSERTTVVHDRHIP-YAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHTVR 13395
G R V+ ++ ++V VFE++IYW R + K G + + L G V+
Sbjct: 2263 GENREVVLASNNMDMFSVSVFESYIYWSDRTHANGSI--KRGSKDNATDSVSLRTGIGVQ 2320
Query: 13396 VSQ----KYAKDTQRTVSGCERAQCSHLCVSLPSTGFACLCPDGIVPQLDGSC 13542
+ A+ V C LC+ + C C G++ + SC
Sbjct: 2321 LKDIKVFNRARQQGTNVCKVNNGGCEQLCLFRGNGQRTCACAHGMLAEDGCSC 2373
Score = 61.2 bits (147), Expect = 7e-07
Identities = 63/241 (26%), Positives = 85/241 (35%), Gaps = 7/241 (2%)
Frame = +1
Query: 8356 SEPAKECLPPYNFQCGDG-SCILLGATCDSKPDCADASDENPNYCN----TRSCPEDYNL 8520
S K C P F C DG +CI G CD + DC D SDE P+ C R P +Y
Sbjct: 10 SSAPKTCSPK-QFVCKDGVTCISKGWRCDREKDCPDGSDEEPDVCPHSTVARCPPNEYRC 68
Query: 8521 CTNRRCIDSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCH 8700
CI ++ CN + DC DG DE A FP + ++ G
Sbjct: 69 GGTEVCIHMSRLCNGVPDCTDGWDEGPHCRGSAARAVHFPETFTLSCSEEAPLTGR---R 125
Query: 8701 DEQVSDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQ 8880
E +++ SL C + CG + +C +
Sbjct: 126 RELITNCSLRGC-----------------------------QESCGITPTGSACYCKS-- 154
Query: 8881 CAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKI--CVGDYLFQCDNLK 9054
Y P G+ + +C CS +CT+T G CV YL Q DN
Sbjct: 155 ---GYEIGPDGKACKDFDECSVYGTCSQ-------SCTNTNGGYTCSCVEGYLPQPDNRS 204
Query: 9055 C 9057
C
Sbjct: 205 C 205
Score = 61.2 bits (147), Expect = 7e-07
Identities = 30/74 (40%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Frame = +1
Query: 11512 EFRCATSGKCIPRRWMCDTENDCGDNSDELDASC-GGTTRPCSESEFRCNDGK-CIPGSK 11685
+F C CI + W CD E DC D SDE C T C +E+RC + CI S+
Sbjct: 20 QFVCKDGVTCISKGWRCDREKDCPDGSDEEPDVCPHSTVARCPPNEYRCGGTEVCIHMSR 79
Query: 11686 VCDGTIQCSDGLDE 11727
+C+G C+DG DE
Sbjct: 80 LCNGVPDCTDGWDE 93
Score = 60.1 bits (144), Expect = 2e-06
Identities = 33/86 (38%), Positives = 42/86 (48%), Gaps = 2/86 (2%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDEKD--CPASTVDCSSQNVFMCADG 447
C Q+ C V+CI++ RCD DC DGSDE+ CP STV N + C
Sbjct: 16 CSPKQFVCKD----GVTCISKGWRCDREKDCPDGSDEEPDVCPHSTVARCPPNEYRCGGT 71
Query: 448 RQCFDVSKKCDGKYDCRDLSDEKDSC 525
C +S+ C+G DC D DE C
Sbjct: 72 EVCIHMSRLCNGVPDCTDGWDEGPHC 97
Score = 49.3 bits (116), Expect = 0.003
Identities = 28/64 (43%), Positives = 33/64 (50%), Gaps = 3/64 (4%)
Frame = +1
Query: 10852 SDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRI---CPVG 11022
S KTC P +QF C D CI K W CD E DC DGSDE + +C CP
Sbjct: 11 SAPKTCSP----KQFVCK-DGVTCISKGWRCDREKDCPDGSDEEPD-VCPHSTVARCPPN 64
Query: 11023 EFQC 11034
E++C
Sbjct: 65 EYRC 68
Score = 46.6 bits (109), Expect = 0.018
Identities = 59/219 (26%), Positives = 77/219 (34%), Gaps = 25/219 (11%)
Frame = +1
Query: 11233 LCMS-AERNCTAEEFRCNNN-KCIAKAWRXXXXXXXXXXXXETPECAQ----IECKKGWT 11394
LC S A + C+ ++F C + CI+K WR E P+ C
Sbjct: 7 LCFSSAPKTCSPKQFVCKDGVTCISKGWRCDREKDCPDGSDEEPDVCPHSTVARCPPNEY 66
Query: 11395 RCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRW--MCDT 11568
RC + CI CNG DC D DE P C A P + C
Sbjct: 67 RCGGTEVCIHMSRLCNGVPDCTDGWDEG----PHCRG-----SAARAVHFPETFTLSCSE 117
Query: 11569 ENDCGDNSDELDASCGGTTRPCSE--------SEFRCNDGKCI-PGSKVCDGTIQCS-DG 11718
E EL +C + R C E S C G I P K C +CS G
Sbjct: 118 EAPLTGRRRELITNC--SLRGCQESCGITPTGSACYCKSGYEIGPDGKACKDFDECSVYG 175
Query: 11719 LDESQCTLRR------CLPGH-RQCDDGTCIAEHKWCDR 11814
CT C+ G+ Q D+ +C A++ DR
Sbjct: 176 TCSQSCTNTNGGYTCSCVEGYLPQPDNRSCKAKNVPVDR 214
Score = 40.8 bits (94), Expect = 0.98
Identities = 35/134 (26%), Positives = 54/134 (40%), Gaps = 17/134 (12%)
Frame = +1
Query: 8347 GSNSEP-------AKECLPPYNFQCGDGS-CILLGATCDSKPDCADASDENPNYCNTRSC 8502
GS+ EP C PP ++CG CI + C+ PDC D DE P +C +
Sbjct: 45 GSDEEPDVCPHSTVARC-PPNEYRCGGTEVCIHMSRLCNGVPDCTDGWDEGP-HCRGSAA 102
Query: 8503 -----PEDYNLCTNRRCIDSAKKCNHIDDCGDGSDELDC---PSAVACAEGTFPCSNGHC 8658
PE + L + + ++ I +C + C P+ AC C +G+
Sbjct: 103 RAVHFPETFTLSCSEEAPLTGRRRELITNCSLRGCQESCGITPTGSACY-----CKSGYE 157
Query: 8659 IN-QTKVCDGHNDC 8697
I K C ++C
Sbjct: 158 IGPDGKACKDFDEC 171
>gi|38074798|ref|XP_130363.2| low density lipoprotein receptor-related
protein 2 [Mus musculus]
Length = 1363
Score = 756 bits (1952), Expect = 0.0
Identities = 460/1417 (32%), Positives = 679/1417 (47%), Gaps = 71/1417 (5%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKS-------------DQWQC 297
C +FRC++G CI W P C S W C
Sbjct: 28 CGSGNFRCDNGYCIPASWRCDGTRDCLDDTDEIGCPPRSCGSGFFLCPAEGTCIPSSWVC 87
Query: 298 DT-----------------------YTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTV 408
D T + C+ RCD+++DC DGSDE++C T
Sbjct: 88 DQDKDCSDGADEQQNCPGTTCSSQQLTCSNGQCVPIEYRCDHVSDCPDGSDERNCYYPTC 147
Query: 409 DCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCI 588
D CA+G C++ S+KCD K DCRD SDE + C+ T C Q +F+C +CI
Sbjct: 148 D-----QLTCANGA-CYNTSQKCDHKVDCRDSSDEAN-CT---TLCSQKEFQCGSG-ECI 196
Query: 589 QKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDE 768
+++VCD DC D SDE + C + C ++F C N +C + + CD DDC D+ DED
Sbjct: 197 LRAYVCDHDNDCEDNSDEHN-CNYDTCGGHQFTCSNGQCINQNWVCDGDDDCQDSGDEDG 255
Query: 769 CGE----YRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQ------CSQNLCPSLG 918
C + C P +W CPG+G CI K+CDG DC +G DE C LC L
Sbjct: 256 CESNQRHHTCYPREWACPGSGRCISMDKVCDGVPDCPEGEDENNATSGRYCGTGLCSILN 315
Query: 919 CQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGD 1098
C+ CH +P+GGEC CP G+ ++ RTC D ++C +G CDQ C + + C C
Sbjct: 316 CEYQCHQTPYGGECFCPPGHIINSNDSRTCIDFDDCQIWGICDQKCESRQGRHQCLCEEG 375
Query: 1099 CFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGL-YRLNPKNPDEEVKKLASGEF 1275
+ +H D+ + SN D L V G +R+ ++ + +
Sbjct: 376 YILERGQHCKSNDSFSAASIIFSNGRD---LLVGDLHGRNFRILAESKNRGI-------- 424
Query: 1276 IYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTL 1455
+ G+DF Y ++FWTD + FS D++ +I +S+ + P LAVDWI N L
Sbjct: 425 VMGVDFHYQKHRVFWTDPMQAKVFSTDINGLNT-QEILNVSIDA---PENLAVDWINNKL 480
Query: 1456 YIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTN------QLKLEAA 1617
Y++E+ RIDV + +G +R L+ + L P IALDP G +FF++ Q K+E A
Sbjct: 481 YLVETRVNRIDVVNLEGNQRVTLITENLGHPRGIALDPTVGYLFFSDWGSLSGQPKVERA 540
Query: 1618 AMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVV 1797
MDG+NR+ LV T +GI +D+ +KRVYWVD + D +E++ Y G R+ VA+G ++V
Sbjct: 541 FMDGSNRKDLVTTKLGWPAGITLDLVSKRVYWVDSRYDYIETVTYDGIQRKTVARGGSLV 600
Query: 1798 PHPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGP 1977
PHPFG++LF++++++TDWT++ V++ KF ++ ++++ P G++ YH + QP
Sbjct: 601 PHPFGISLFEEHVFFTDWTKMAVMKANKFTDTNPQVYH--QSSLTPFGVTVYHALRQP-- 656
Query: 1978 GQSECLAMKIENPC--TNADCEGMCILSKDNGGFGVGYKCACPIGQKL-VNGKRCIDSID 2148
NPC N C +C+LS G+GY+C C G +L + C+ +
Sbjct: 657 --------NATNPCGNNNGGCAQICVLSHRTDNGGLGYRCKCEFGFELDADEHHCVAVKN 708
Query: 2149 YLLFSSNKIVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDN 2328
+LLFSS VRGI + ++P++ +G+ F D ++ FY+D+ N
Sbjct: 709 FLLFSSQTAVRGI--PFTLSTQEDVMVPVTGSPSFFVGIDF----DAQHSTIFYSDLSKN 762
Query: 2329 TIYRIRPDGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDE 2508
IY+ + DG G + + +SFDWIS+ LY+ D S+ V+K+ +
Sbjct: 763 IIYQQKIDGTGKEVITANRLQNVECLSFDWISRNLYWTDGGSKSVTVMKLADKS------ 816
Query: 2509 LVRRQLITELRDPVSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEM 2688
RRQ+I+ L +P S+VVHP G +F ++ RPA I R DG + I NT+LG P+ +
Sbjct: 817 --RRQIISNLNNPRSIVVHPAAGYMFLSDWFRPAKIMRAWSDGSHLMPIVNTSLGWPNGL 874
Query: 2689 AIDFAENRLCWGDTLLKTISCMDFDGKNVVKLDIDNPI--PVAITIMNEYIYYVHQRPYS 2862
AID++ +RL W D I + DG + +L + + P +T+ + ++ R +
Sbjct: 875 AIDWSTSRLYWVDAFFDKIEHSNLDGLDRKRLGHVDQMTHPFGLTVFKDNVFLTDWRLGA 934
Query: 2863 IRRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATP 3042
I RV K +GG +VR SI +KA Q + + C+ CF P
Sbjct: 935 IIRVRKSDGGDMTVVRR---GISSIMHVKAYDADLQTGTNYCSQTTHPNGDCSHFCFPVP 991
Query: 3043 SESHPNELEAKCACRQGFMINKENNHSCQKDPA-EKIEQLCSSNSTQFQCKNGRCIPKEW 3219
+ + C C G + ++ +C+ DPA E Q C S+S F C NG+C+P +
Sbjct: 992 N------FQRVCGCPYGMKLQRD-QMTCEGDPAREPPTQQCGSSS--FPCNNGKCVPSIF 1042
Query: 3220 KCDGENDCLDESDEIDEKGDKC-FHETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXX 3396
+CDG +DC D SDE +C C+ + C + +CIP Q
Sbjct: 1043 RCDGVDDCHDNSDE-----HQCGALNNTCSSSAFTCVHGGQCIPGQWRCDKQND------ 1091
Query: 3397 XXVKYCKDGQ----------KPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMC 3546
C DG C F CDNH CIP++W EK
Sbjct: 1092 -----CLDGSDEQNCPTRSPSSTCPPTSFTCDNHMCIPKEWVCDTDNDCSDGSDEK-NCQ 1145
Query: 3547 GNATCAANQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQCV 3726
+ TC QF C + RCI ++CDGD DC DG+DE C + C++ QF+CA+G C+
Sbjct: 1146 ASGTCHPTQFRCPDHRCISPLYVCDGDKDCVDGSDE--AGC-VLNCTSSQFKCADGSSCI 1202
Query: 3727 PLRNHXXXXXXXXXXXXXXXXAVTAES-CTPDQFKCVSSGLCIPASWKXXXXXXXXXXSD 3903
R C PD+F+C G CIP +W+ SD
Sbjct: 1203 NSRYRCDGVYDCKDNSDEAGCPTRPPGMCHPDEFQCQGDGTCIPNTWECDGHPDCIQGSD 1262
Query: 3904 EPKFGCTSGRQCSSDQFKCGNGRCILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPF 4083
E GC + CS F C NG CI N+W+CDG+NDC D SD E+ C T CP
Sbjct: 1263 EHN-GCVP-KTCSPSHFLCDNGNCIYNSWVCDGDNDCRDMSD---EKDCPT--QPFHCPS 1315
Query: 4084 EHVACENDQETCIPLHQLCDGKTHCPGGTDEGGRCAR 4194
C C+ L LCDG CP GTDE C++
Sbjct: 1316 SQWQCPG-YSICVNLSALCDGVFDCPNGTDESPLCSK 1351
Score = 429 bits (1104), Expect = e-118
Identities = 304/1042 (29%), Positives = 465/1042 (44%), Gaps = 67/1042 (6%)
Frame = +1
Query: 3436 CAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNATCAANQFSC-ANGRCIPIYW 3612
C + F+CDN CIP W+ E C +C + F C A G CIP W
Sbjct: 28 CGSGNFRCDNGYCIPASWRCDGTRDCLDDTDEI--GCPPRSCGSGFFLCPAEGTCIPSSW 85
Query: 3613 LCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQCVPLRNHXXXXXXXXXXXXXXXXA 3792
+CD D DC DG DE ++ CP CS+ Q C+NG QCVP+
Sbjct: 86 VCDQDKDCSDGADE-QQNCPGTTCSSQQLTCSNG-QCVPIEYRCDHVSDCPDGSDE---- 139
Query: 3793 VTAESC---TPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEP---------KFGCTSGR- 3933
+C T DQ C ++G C S K SDE +F C SG
Sbjct: 140 ---RNCYYPTCDQLTC-ANGACYNTSQKCDHKVDCRDSSDEANCTTLCSQKEFQCGSGEC 195
Query: 3934 -------------------------QCSSDQFKCGNGRCILNNWLCDGENDCGDGSDESS 4038
C QF C NG+CI NW+CDG++DC D DE
Sbjct: 196 ILRAYVCDHDNDCEDNSDEHNCNYDTCGGHQFTCSNGQCINQNWVCDGDDDCQDSGDED- 254
Query: 4039 ERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDE-----GGRCARDLC 4203
GC+++ C AC CI + ++CDG CP G DE G C LC
Sbjct: 255 --GCESNQRHHTCYPREWACPGSGR-CISMDKVCDGVPDCPEGEDENNATSGRYCGTGLC 311
Query: 4204 SADRAGCSFKCHNSPNGPICSCPFGEQLVNKTK---CEPENECLDSSSCSQRCKDEKHGF 4374
S C ++CH +P G C CP G ++N C ++C C Q+C+ +
Sbjct: 312 SI--LNCEYQCHQTPYGGECFCPPGH-IINSNDSRTCIDFDDCQIWGICDQKCESRQGRH 368
Query: 4375 TCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGAIVENAIALA 4554
C C+EGY L+ + CK D+ I SN + D N+ I +
Sbjct: 369 QCLCEEGYILERGQH-CKSNDSFSAASIIFSNGRDLLVGDLHGRNFRILAESKNRGIVMG 427
Query: 4555 WDS--LTDRIYWSDIREKKILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVDSSL 4728
D R++W+D + K+ S + NG N + +D E +A+DW+ LY V++ +
Sbjct: 428 VDFHYQKHRVFWTDPMQAKVFSTDINGLNTQEILNVSIDAPENLAVDWINNKLYLVETRV 487
Query: 4729 NTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQ---NPCIERASMDGTD 4899
N I+V NLE QR L+ +N+ PRGIA+DP G +F++DWG P +ERA MDG++
Sbjct: 488 NRIDVVNLEG-NQRVTLITENLGHPRGIALDPTVGYLFFSDWGSLSGQPKVERAFMDGSN 546
Query: 4900 RQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHAL 5079
R+ +V TK+ WP I LD + RVY+ DS+ D+I+ V YDG R V V HP +
Sbjct: 547 RKDLVTTKLGWPAGITLDLVSKRVYWVDSRYDYIETVTYDGIQRKTVARGGSLVPHPFGI 606
Query: 5080 AIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCST 5259
++FE+ ++++D + K+ + Y + + GV H + QP NPC
Sbjct: 607 SLFEEHVFFTDWTKMAVMKANKFTDTNPQVYHQSSLT-PFGVTVYHALRQP-NATNPCGN 664
Query: 5260 N--PCSHLCLLNNKNT-----FTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNVFGIEM 5418
N C+ +C+L+++ + CKC G +LDA C+ K FL+ +T V GI
Sbjct: 665 NNGGCAQICVLSHRTDNGGLGYRCKCEFGFELDADEHHCV-AVKNFLLFSSQTAVRGIPF 723
Query: 5419 NSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRST 5598
+++++ V P +G FDA H+ + + IY+
Sbjct: 724 TLSTQEDVMVPVTGSPSFFVGIDFDA---------------QHSTIFYSDLSKNIIYQQK 768
Query: 5599 VNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVI--LSND 5772
++G K + ++ + + CL FDW RNL + ++++ +++ K R +I L+N
Sbjct: 769 IDGTGKEVITANRL-QNVECLSFDWISRNLYWTDGGSKSVTVMKLADKSRRQIISNLNNP 827
Query: 5773 QSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIA 5952
+S GY+F D AK+ RA DGS+ + I + L + +A
Sbjct: 828 RSIVVHPAA---------GYMFLSD---WFRPAKIMRAWSDGSHLMPIVNTSLGWPNGLA 875
Query: 5953 IDTTNTRVYFSEAKAGRISSVTYDGQDRHYV-LSDGGRQPNGLAFYGDRLFYADSAFDS- 6126
ID + +R+Y+ +A +I DG DR + D P GL + D +F D +
Sbjct: 876 IDWSTSRLYWVDAFFDKIEHSNLDGLDRKRLGHVDQMTHPFGLTVFKDNVFLTDWRLGAI 935
Query: 6127 IEVATINGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHIN---NGNCDHICIPLM 6297
I V +G T ++ + ++ ++KA + + C NG+C H C P+
Sbjct: 936 IRVRKSDGGDM----TVVRRGISSIMHVKAYDADLQTGTNYCSQTTHPNGDCSHFCFPVP 991
Query: 6298 FAQRTCTCANGY-VKDGQTSCK 6360
QR C C G ++ Q +C+
Sbjct: 992 NFQRVCGCPYGMKLQRDQMTCE 1013
Score = 377 bits (968), Expect = e-102
Identities = 233/772 (30%), Positives = 357/772 (46%), Gaps = 18/772 (2%)
Frame = +1
Query: 8608 SAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPGLPIDCRGVKVRCPNT 8787
S C G F C NG+CI + CDG DC D+ +DE CP P C CP
Sbjct: 24 SGQECGSGNFRCDNGYCIPASWRCDGTRDCLDD--TDE--IGCP--PRSCGSGFFLCPAE 77
Query: 8788 NICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCIPETWQCDGDNDCSDG 8967
CI + +CD DC D ADE Q C C+ + C +G+C+P ++CD +DC DG
Sbjct: 78 GTCIPSSWVCDQDKDCSDGADEQQN-CPGTTCSSQQLTCSNGQCVPIEYRCDHVSDCPDG 136
Query: 8968 WDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXXXXXXHSRHGCGNRTC 9147
DE NC Y CD L C + A
Sbjct: 137 SDER--NC------------YYPTCDQLTCANGA-------------------------- 156
Query: 9148 TDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECNKGEFRCSN 9327
C + CD V C DE+ C T C++ EF+C +
Sbjct: 157 -------------------CYNTSQKCDHKVDCRDSSDEAN--CTTL---CSQKEFQCGS 192
Query: 9328 QHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCANHKCVPNSWKCDGNDDCEDGS 9507
CI + CD DNDC D SDEH NC Y +C F C+N +C+ +W CDG+DDC+D
Sbjct: 193 GECILRAYVCDHDNDCEDNSDEH-NCNYDTCGGHQFTCSNGQCINQNWVCDGDDDCQDSG 251
Query: 9508 DEKDCPKNSASAQKASKCSNGQFQCT-SGECIDDAKVCDRNFDCTDRSDESSL-----CF 9669
DE C N Q+ C ++ C SG CI KVCD DC + DE++ C
Sbjct: 252 DEDGCESN----QRHHTCYPREWACPGSGRCISMDKVCDGVPDCPEGEDENNATSGRYCG 307
Query: 9670 IDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNECYE-GISGCSQKCD 9846
CS+ CE +C G +C C G I+ +D ++C + ++C GI C QKC+
Sbjct: 308 TGLCSILN---CEYQCHQTPYGGECFCPPGHIINSNDSRTCIDFDDCQIWGI--CDQKCE 362
Query: 9847 DKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYELAAQGFD 10026
+ G ++C C +GY L H CK + + +N + + G + + A+ +
Sbjct: 363 SRQGRHQCLCEEGYILERGQH-CKSNDSFSAASIIFSNGRDLLVGDLHGRNFRILAESKN 421
Query: 10027 N--VVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDWV 10200
V+ +D + + + D + ++ D++ +++ + +L ++ E +AVDW+
Sbjct: 422 RGIVMGVDFHYQKHRVFWTDPMQAKVFSTDINGLNT-----QEILNVSIDAPENLAVDWI 476
Query: 10201 GRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFFTEW---SLQPY 10371
KLY++ + I V L+G TLI + + P+ I + P GYLFF++W S QP
Sbjct: 477 NNKLYLVETRVNRIDVVNLEGNQRVTLITENLGHPRGIALDPTVGYLFFSDWGSLSGQPK 536
Query: 10372 IGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRR 10551
+ R +DGS L LGWP I +D S R++W D+ + I + +DG R+
Sbjct: 537 VERAFMDGSNRKD-----LVTTKLGWPAGITLDLVSKRVYWVDSRYDYIETVTYDGIQRK 591
Query: 10552 HIP--AQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDLRIVH 10725
+ H + +F++++++ DW V++ +K+T N + ++ P + + H
Sbjct: 592 TVARGGSLVPHPFGISLFEEHVFFTDWTKMAVMKANKFTDTNPQVYHQSSLTPFGVTVYH 651
Query: 10726 PMRQPAYPNPCGDNNGGCSHLCLIG----AGGNGYTCSCPDQFVLLSDQKTC 10869
+RQP NPCG+NNGGC+ +C++ GG GY C C F L +D+ C
Sbjct: 652 ALRQPNATNPCGNNNGGCAQICVLSHRTDNGGLGYRCKCEFGFELDADEHHC 703
Score = 310 bits (794), Expect = 7e-82
Identities = 276/1092 (25%), Positives = 464/1092 (42%), Gaps = 44/1092 (4%)
Frame = +1
Query: 6265 GNCDHICIPLMFAQRTCTCANGYVKDGQTSCKLFDE----SFVIVATKTKVIG------- 6411
G CD C + C C GY+ + CK D S + + ++G
Sbjct: 355 GICDQKCESRQ-GRHQCLCEEGYILERGQHCKSNDSFSAASIIFSNGRDLLVGDLHGRNF 413
Query: 6412 YPIDETQSKGVAMEPIGGLSITGVDYDYESKTIYVAEASGINKGITAYTIGESSPRAVIR 6591
+ E++++G+ M GVD+ Y+ ++ + + + + I + + ++
Sbjct: 414 RILAESKNRGIVM---------GVDFHYQKHRVFWTDP--MQAKVFSTDINGLNTQEILN 462
Query: 6592 DSIGSLTIKSLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDP 6771
SI + ++LA+DWIN +Y + R I+V L+G R L+T P IA+DP
Sbjct: 463 VSIDAP--ENLAVDWINNKLYLVETRVNR--IDVVNLEGNQRVTLITENLGHPRGIALDP 518
Query: 6772 VSRYLYWADQGQ---KPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMD 6942
YL+++D G +P ++R+F+DGS R+ +V++ + P + +D+ SK +YW D++ D
Sbjct: 519 TVGYLFFSDWGSLSGQPKVERAFMDGSNRKDLVTTKLGWPAGITLDLVSKRVYWVDSRYD 578
Query: 6943 GIYRVRSTGGTPELVR---SDIASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLS 7113
I V G + V S + G++L +++++TD K+ A K N+ +
Sbjct: 579 YIETVTYDGIQRKTVARGGSLVPHPFGISLFEEHVFFTD--WTKM--AVMKANKFTDTNP 634
Query: 7114 PTTVAASLKDIGDVAVFSSNNQPRASSPCQITDNLRKSPCTQLCFATPGTQTP----TCS 7281
+SL G V V+ + QP A++PC C Q+C + T C
Sbjct: 635 QVYHQSSLTPFG-VTVYHALRQPNATNPC----GNNNGGCAQICVLSHRTDNGGLGYRCK 689
Query: 7282 CARGV---LKGRTCEEPDTYIMFSDGDKIIDVAIEPDVKASRPLKDPFPEISNLQTFDVD 7452
C G C +++FS + + + +D ++ +F V
Sbjct: 690 CEFGFELDADEHHCVAVKNFLLFSSQTAVRGIPFTLSTQ-----EDVMVPVTGSPSFFVG 744
Query: 7453 VNLRRVYFVV-ESPVGVNISWFSMNNAENPRLVFGASKQPHAKEIRHISDMKLDWLTQKI 7629
++ + + S + NI + + ++ A ++++ + DW+++ +
Sbjct: 745 IDFDAQHSTIFYSDLSKNIIYQQKIDGTGKEVIT-------ANRLQNVECLSFDWISRNL 797
Query: 7630 YFTTGRGGKVMAIDTAGEHLSTIASG-DWTYALAIDPCSGLLFWSDSGYKTSGGLYEP-R 7803
Y+T G V + A + I S + ++ + P +G +F SD + P +
Sbjct: 798 YWTDGGSKSVTVMKLADKSRRQIISNLNNPRSIVVHPAAGYMFLSD--------WFRPAK 849
Query: 7804 IERSNLAGGSRKVIVSESISLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASG 7983
I R+ G IV+ S+ P +A+D+ ++YW D IE ++ DG +RK +
Sbjct: 850 IMRAWSDGSHLMPIVNTSLGWPNGLAIDWSTSRLYWVDAFFDKIEHSNLDGLDRKRLGHV 909
Query: 7984 YRAK---SLDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESDVR 8154
+ L ++ ++++D + R+ K G + V R I + V A ++D++
Sbjct: 910 DQMTHPFGLTVFKDNVFLTDWRLGAIIRVRKSDGGDM--TVVRRGISSIMHVKAYDADLQ 967
Query: 8155 TRNQVCNALTSQLCKTDNGGCDQLCTVVAD-------DIGLAASKVQCSCNDTYELVQEP 8313
T C+ T NG C C V + G+ + Q +C +P
Sbjct: 968 TGTNYCSQTTHP-----NGDCSHFCFPVPNFQRVCGCPYGMKLQRDQMTCEG------DP 1016
Query: 8314 GKDYPTQCVLRGSNSEPAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNT 8493
++ PTQ GS+S F C +G C+ CD DC D SDE+
Sbjct: 1017 AREPPTQQC--GSSS-----------FPCNNGKCVPSIFRCDGVDDCHDNSDEHQCGALN 1063
Query: 8494 RSCPEDYNLCTNR-RCIDSAKKCNHIDDCGDGSDELDCPS---AVACAEGTFPCSNGHCI 8661
+C C + +CI +C+ +DC DGSDE +CP+ + C +F C N CI
Sbjct: 1064 NTCSSSAFTCVHGGQCIPGQWRCDKQNDCLDGSDEQNCPTRSPSSTCPPTSFTCDNHMCI 1123
Query: 8662 NQTKVCDGHNDCHDEQVSDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGD 8841
+ VCD NDC D SDE G C + RCP+ CI P +CDG DC D
Sbjct: 1124 PKEWVCDTDNDCSDG--SDEKNCQASGT---CHPTQFRCPDHR-CISPLYVCDGDKDCVD 1177
Query: 8842 KADENQLFCMNQQCAQHYVRCPSGR-CIPETWQCDGDNDCSDGWDETHTNCTDTAGKKIC 9018
+DE C +C G CI ++CDG DC D DE C T +C
Sbjct: 1178 GSDEAGCVL---NCTSSQFKCADGSSCINSRYRCDGVYDCKDNSDEA--GCP-TRPPGMC 1231
Query: 9019 VGDYLFQCD-NLKCISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQP 9195
D FQC + CI + H+ GC +TC+ F C +
Sbjct: 1232 HPDE-FQCQGDGTCIPNTWECDGHPDCIQGSDEHN--GCVPKTCSPSHFLCDNG------ 1282
Query: 9196 KYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECNKGEFRCSNQH-CIHSTWECDGDND 9372
CI +W+CDGD C DE C T+ C +++C C++ + CDG D
Sbjct: 1283 --NCIYNSWVCDGDNDCRDMSDEKD--CPTQPFHCPSSQWQCPGYSICVNLSALCDGVFD 1338
Query: 9373 CLDGSDEHANCT 9408
C +G+DE C+
Sbjct: 1339 CPNGTDESPLCS 1350
Score = 293 bits (749), Expect = 1e-76
Identities = 220/814 (27%), Positives = 326/814 (40%), Gaps = 27/814 (3%)
Frame = +1
Query: 9802 NECYEGISGCSQKC------DDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANK 9963
N C GC+Q C D+ Y+C C G++L +D+H C + + F L +++
Sbjct: 660 NPCGNNNGGCAQICVLSHRTDNGGLGYRCKCEFGFELDADEHHC----VAVKNFLLFSSQ 715
Query: 9964 HYIRKISIDGNKYE---LAAQGFDNV-VSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSP 10131
+R I + E + G + V +D D + D K + + +D
Sbjct: 716 TAVRGIPFTLSTQEDVMVPVTGSPSFFVGIDFDAQHSTIFYSDLSKNIIYQQKIDG---- 771
Query: 10132 LSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKA 10311
+ E + + + E ++ DW+ R LY + +S+ V +L + + +I + + P++
Sbjct: 772 -TGKEVITANRLQNVECLSFDWISRNLYWTDGGSKSVTVMKLADKSRRQIISN-LNNPRS 829
Query: 10312 IVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLF 10491
IVVHP GY+F ++W I R DGS + + LGWPN +AID+ + RL+
Sbjct: 830 IVVHPAAGYMFLSDWFRPAKIMRAWSDGSH-----LMPIVNTSLGWPNGLAIDWSTSRLY 884
Query: 10492 WGDAHLNEIGFMDFDGNGRRHI-PAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGK 10668
W DA ++I + DG R+ + + +H + VF D ++ DW L ++R K G
Sbjct: 885 WVDAFFDKIEHSNLDGLDRKRLGHVDQMTHPFGLTVFKDNVFLTDWRLGAIIRVRKSDGG 944
Query: 10669 NETILKKTVQLPNDLRIVHPMRQPA--YPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQF 10842
+ T++++ + ++ Q Y + NG CSH C C CP
Sbjct: 945 DMTVVRRGISSIMHVKAYDADLQTGTNYCSQTTHPNGDCSHFC-FPVPNFQRVCGCPYGM 1003
Query: 10843 VLLSDQKTCE---------PNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESI 10995
L DQ TCE C F C ++ KC+P ++ CDG DC D SDE
Sbjct: 1004 KLQRDQMTCEGDPAREPPTQQCGSSSFPC--NNGKCVPSIFRCDGVDDCHDNSDE----- 1056
Query: 10996 CGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXXEQNCDKACDPWMFKCAATGRCIPR 11175
H C + C F C G+CIP
Sbjct: 1057 ---------------HQCGA-------------------LNNTCSSSAFTCVHGGQCIPG 1082
Query: 11176 RFTXXXXXXXXXRSDEADTLCMSAERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXET 11355
++ SDE + S C F C+N+ CI K W E
Sbjct: 1083 QWRCDKQNDCLDGSDEQNCPTRSPSSTCPPTSFTCDNHMCIPKEWVCDTDNDCSDGSDEK 1142
Query: 11356 PECAQIECKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSG 11535
A C RC +RCI C+G DC D SDE C +F+CA
Sbjct: 1143 NCQASGTCHPTQFRC-PDHRCISPLYVCDGDKDCVDGSDE--AGCVLNCTSSQFKCADGS 1199
Query: 11536 KCIPRRWMCDTENDCGDNSDELDASCGGTTRP---CSESEFRC-NDGKCIPGSKVCDGTI 11703
CI R+ CD DC DNSDE G TRP C EF+C DG CIP + CDG
Sbjct: 1200 SCINSRYRCDGVYDCKDNSDE----AGCPTRPPGMCHPDEFQCQGDGTCIPNTWECDGHP 1255
Query: 11704 QCSDGLDE-SQCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCS 11880
C G DE + C + C P H CD+G CI CD DC + +DE + C
Sbjct: 1256 DCIQGSDEHNGCVPKTCSPSHFLCDNGNCIYNSWVCDGDNDCRDMSDE--------KDCP 1307
Query: 11881 PFEFECANSVCIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQL 12060
F C P +++C +C+N+ L
Sbjct: 1308 TQPFHC-----------------------------------PSSQWQCPGYSICVNLSAL 1332
Query: 12061 CNGFNDCGPNDFSDEHLSMCSSFSEYGDCSSDQF 12162
C+G DC PN + L CS F ++ ++ F
Sbjct: 1333 CDGVFDC-PNGTDESPL--CSKFPDHSLLDTNLF 1363
Score = 253 bits (646), Expect = 1e-64
Identities = 195/730 (26%), Positives = 302/730 (40%), Gaps = 16/730 (2%)
Frame = +1
Query: 11374 ECKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRR 11553
EC G RC + Y CIP C+G DC D++DE +C G F C G CIP
Sbjct: 27 ECGSGNFRCDNGY-CIPASWRCDGTRDCLDDTDEIGCPPRSCGS-GFFLCPAEGTCIPSS 84
Query: 11554 WMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQ 11733
W+CD + DC D +DE +C GTT CS + C++G+C+P CD C DG DE
Sbjct: 85 WVCDQDKDCSDGADE-QQNCPGTT--CSSQQLTCSNGQCVPIEYRCDHVSDCPDGSDERN 141
Query: 11734 CTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFECANSVC 11913
C C C +G C + CD K DC +++DE +C + CS EF+C + C
Sbjct: 142 CYYPTC--DQLTCANGACYNTSQKCDHKVDCRDSSDEANCTTL----CSQKEFQCGSGEC 195
Query: 11914 IPRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPND 12093
I R ++ SDE + C C +F C++ + C+N +C+G +DC D
Sbjct: 196 ILRAYVCDHDNDCEDNSDEHN--CNYDTCGGH-QFTCSNGQ-CINQNWVCDGDDDC--QD 249
Query: 12094 FSDEHLSMCSSFSEYGDCSSDQFKC-ANGKCVNGTVACDRKDDCGDASDEIGCS--KHGG 12264
DE C S + C ++ C +G+C++ CD DC + DE + ++ G
Sbjct: 250 SGDE--DGCESNQRHHTCYPREWACPGSGRCISMDKVCDGVPDCPEGEDENNATSGRYCG 307
Query: 12265 KTSCEAFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLN 12444
C C++ C G C C G + + CID D+C C Q C +
Sbjct: 308 TGLCSILN----CEYQCHQTPYGGECFCPPGHIINSNDSRTCIDFDDCQIWGICDQKCES 363
Query: 12445 TKGSYLCRCHEDYENNVVVGSMTGKDCRAKG--DAANVMIGADDSLVQLSLHGSGTNRHX 12618
+G + C C E Y G+ C++ AA+++ L+ LHG
Sbjct: 364 RQGRHQCLCEEGYILE------RGQHCKSNDSFSAASIIFSNGRDLLVGDLHG---RNFR 414
Query: 12619 XXXXXXXXXXXXXXXXXPRKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVV 12798
+K ++W D + ++ + I NG + E + +D
Sbjct: 415 ILAESKNRGIVMGVDFHYQKHRVFWTDPMQAKVFSTDI-NGLNTQEILNVSID------A 467
Query: 12799 PTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIV 12978
P +AVD+ L+ LV R R ID N +G ++
Sbjct: 468 PENLAVDWINNKLY-----------LVETRVNR----IDVVNL--------EGNQRVTLI 504
Query: 12979 AGHLQQPTALITAPSAGRICYSDAGL---HAKIECADMDGTHRQIIVKDLVFSPTSMAID 13149
+L P + P+ G + +SD G K+E A MDG++R+ +V + P + +D
Sbjct: 505 TENLGHPRGIALDPTVGYLFFSDWGSLSGQPKVERAFMDGSNRKDLVTTKLGWPAGITLD 564
Query: 13150 EGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHI---PYAVDVFENHIYWLSRESKTL 13320
R+YWVD +Y ++ V DG +R TV + P+ + +FE H+++ +
Sbjct: 565 L-VSKRVYWVDSRYDYIETVTYDGIQRKTVARGGSLVPHPFGISLFEEHVFFTDWTKMAV 623
Query: 13321 YVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPST---- 13488
+KF V V V + G C+ +CV T
Sbjct: 624 MKANKFTDTNPQVYHQSSLTPFGVTVYHALRQPNATNPCGNNNGGCAQICVLSHRTDNGG 683
Query: 13489 -GFACLCPDG 13515
G+ C C G
Sbjct: 684 LGYRCKCEFG 693
Score = 226 bits (576), Expect = 1e-56
Identities = 178/639 (27%), Positives = 264/639 (40%), Gaps = 18/639 (2%)
Frame = +1
Query: 7804 IERSNLAGGSRKVIVSESISLPAAIAVDFRNQKIYWADVNRLNIEVADY-DGQNRKVIAS 7980
I + + G ++VI + + ++ D+ ++ +YW D ++ V D R++I++
Sbjct: 764 IYQQKIDGTGKEVITANRLQNVECLSFDWISRNLYWTDGGSKSVTVMKLADKSRRQIISN 823
Query: 7981 GYRAKSLDIWDR--WLYMSDPLSNGVFRIDKESGSGLENVVSDRR-IPGALRVFASESDV 8151
+S+ + ++++SD GS L +V+ P L + S S +
Sbjct: 824 LNNPRSIVVHPAAGYMFLSDWFRPAKIMRAWSDGSHLMPIVNTSLGWPNGLAIDWSTSRL 883
Query: 8152 RTRNQVCNALT-SQLCKTDN---GGCDQLC-----TVVADDIGLAASKVQCSCNDTYELV 8304
+ + + S L D G DQ+ TV D++ L ++ ++
Sbjct: 884 YWVDAFFDKIEHSNLDGLDRKRLGHVDQMTHPFGLTVFKDNVFLTDWRLGA-------II 936
Query: 8305 QEPGKDYPTQCVLRGSNSEPAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNY 8484
+ D V+R S + Q G C T DC+ PN+
Sbjct: 937 RVRKSDGGDMTVVRRGISSIMHVKAYDADLQTGTNYC---SQTTHPNGDCSHFCFPVPNF 993
Query: 8485 CNTRSCPEDYNLCTNRRCIDSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCSNGHCIN 8664
CP L ++ + GD + E P C +FPC+NG C+
Sbjct: 994 QRVCGCPYGMKLQRDQMTCE-----------GDPARE---PPTQQCGSSSFPCNNGKCVP 1039
Query: 8665 QTKVCDGHNDCHDEQVSDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDK 8844
CDG +DCHD SDE C L C C + CI CD +DC D
Sbjct: 1040 SIFRCDGVDDCHDN--SDEH--QCGALNNTCSSSAFTCVHGGQCIPGQWRCDKQNDCLDG 1095
Query: 8845 ADENQLFCMNQQ--CAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKIC 9018
+DE + C C + CIP+ W CD DNDCSDG DE + + T
Sbjct: 1096 SDEQNCPTRSPSSTCPPTSFTCDNHMCIPKEWVCDTDNDCSDGSDEKNCQASGTCHPT-- 1153
Query: 9019 VGDYLFQCDNLKCISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPK 9198
F+C + +CIS ++ GC CT +F C +
Sbjct: 1154 ----QFRCPDHRCISPLYVCDGDKDCVDGS---DEAGCV-LNCTSSQFKCADGSS----- 1200
Query: 9199 YECIPRAWLCDGDVTCAGGEDESTELCKTEKKE-CNKGEFRCSNQH-CIHSTWECDGDND 9372
CI + CDG C DE+ C T C+ EF+C CI +TWECDG D
Sbjct: 1201 --CINSRYRCDGVYDCKDNSDEAG--CPTRPPGMCHPDEFQCQGDGTCIPNTWECDGHPD 1256
Query: 9373 CLDGSDEHANCTYSSCQPDFFQCANHKCVPNSWKCDGNDDCEDGSDEKDCPKNSASAQKA 9552
C+ GSDEH C +C P F C N C+ NSW CDG++DC D SDEKDCP +
Sbjct: 1257 CIQGSDEHNGCVPKTCSPSHFLCDNGNCIYNSWVCDGDNDCRDMSDEKDCP------TQP 1310
Query: 9553 SKCSNGQFQCTS-GECIDDAKVCDRNFDCTDRSDESSLC 9666
C + Q+QC C++ + +CD FDC + +DES LC
Sbjct: 1311 FHCPSSQWQCPGYSICVNLSALCDGVFDCPNGTDESPLC 1349
Score = 176 bits (446), Expect = 1e-41
Identities = 93/254 (36%), Positives = 121/254 (47%), Gaps = 4/254 (1%)
Frame = +1
Query: 148 SSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPG-CKSDQWQCDTYTWHSVS 324
SS C F C++ CI EW G C Q++C +
Sbjct: 1107 SSTCPPTSFTCDNHMCIPKEWVCDTDNDCSDGSDEKNCQASGTCHPTQFRCPDH-----R 1161
Query: 325 CIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDL 504
CI+ CD DC DGSDE C ++C+S F CADG C + +CDG YDC+D
Sbjct: 1162 CISPLYVCDGDKDCVDGSDEAGC---VLNCTSSQ-FKCADGSSCINSRYRCDGVYDCKDN 1217
Query: 505 SDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEF 684
SDE +R C +F+C CI +W CDG DC GSDE + C K C+ + F
Sbjct: 1218 SDEAGCPTRPPGMCHPDEFQCQGDGTCIPNTWECDGHPDCIQGSDEHNGCVPKTCSPSHF 1277
Query: 685 QCKNKRCQPRKFRCDYYDDCGDNSDEDEC--GEYRCPPGKWNCPGTGHCIDQLKLCDGSK 858
C N C + CD +DC D SDE +C + CP +W CPG C++ LCDG
Sbjct: 1278 LCDNGNCIYNSWVCDGDNDCRDMSDEKDCPTQPFHCPSSQWQCPGYSICVNLSALCDGVF 1337
Query: 859 DCADGADEQQ-CSQ 897
DC +G DE CS+
Sbjct: 1338 DCPNGTDESPLCSK 1351
Score = 176 bits (445), Expect = 2e-41
Identities = 121/356 (33%), Positives = 156/356 (42%), Gaps = 11/356 (3%)
Frame = +1
Query: 11221 EADTLCMSAERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXETPECAQIE--CKKGWT 11394
E D + C + F CNN KC+ +R E +C + C
Sbjct: 1013 EGDPAREPPTQQCGSSSFPCNNGKCVPSIFRCDGVDDCHDNSDEH-QCGALNNTCSSSAF 1071
Query: 11395 RCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVG-----EFRCATSGKCIPRRWM 11559
C +CIP C+ Q+DC D SDE Q CPT F C + CIP+ W+
Sbjct: 1072 TCVHGGQCIPGQWRCDKQNDCLDGSDE--QNCPTRSPSSTCPPTSFTC-DNHMCIPKEWV 1128
Query: 11560 CDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCT 11739
CDT+NDC D SDE + GT C ++FRC D +CI VCDG C DG DE+ C
Sbjct: 1129 CDTDNDCSDGSDEKNCQASGT---CHPTQFRCPDHRCISPLYVCDGDKDCVDGSDEAGCV 1185
Query: 11740 LRRCLPGHRQCDDGT-CIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFEC-ANSVC 11913
L C +C DG+ CI CD DC + +DE C C P EF+C + C
Sbjct: 1186 LN-CTSSQFKCADGSSCINSRYRCDGVYDCKDNSDEAGCPTRPPGMCHPDEFQCQGDGTC 1244
Query: 11914 IPRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPND 12093
IP + SDE + C C P F C + C+ +C+G NDC D
Sbjct: 1245 IPNTWECDGHPDCIQGSDEHNG-CVPKTCSPS-HFLCDNGN-CIYNSWVCDGDNDC--RD 1299
Query: 12094 FSDEHLSMCSSFSEYGDCSSDQFKCANGK-CVNGTVACDRKDDCGDASDEIG-CSK 12255
SDE F C S Q++C CVN + CD DC + +DE CSK
Sbjct: 1300 MSDEKDCPTQPFH----CPSSQWQCPGYSICVNLSALCDGVFDCPNGTDESPLCSK 1351
Score = 152 bits (383), Expect = 3e-34
Identities = 101/351 (28%), Positives = 155/351 (43%), Gaps = 3/351 (0%)
Frame = +1
Query: 4321 CLDSSSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHK 4500
C S R + G+ C C+ G+ELD D+ C N + R + +
Sbjct: 669 CAQICVLSHRTDNGGLGYRCKCEFGFELDADEHHCVAVKNFLLFSSQTAVRGIPFTLSTQ 728
Query: 4501 LDNWHTFGAIVENAIALAWDSLTDRIYWSDIREKKILSANRNGTNATVFIADGLDITEGI 4680
D + + +D+ I++SD+ + I +GT V A+ L E +
Sbjct: 729 EDVMVPVTGSPSFFVGIDFDAQHSTIFYSDLSKNIIYQQKIDGTGKEVITANRLQNVECL 788
Query: 4681 ALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQ 4860
+ DW+ RNLYW D ++ V L D +R ++ N++ PR I V P G MF +DW +
Sbjct: 789 SFDWISRNLYWTDGGSKSVTVMKLADKSRRQII--SNLNNPRSIVVHPAAGYMFLSDWFR 846
Query: 4861 NPCIERASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQV 5040
I RA DG+ IV T + WPN +A+D++T R+Y+ D+ D I+ N DG R +
Sbjct: 847 PAKIMRAWSDGSHLMPIVNTSLGWPNGLAIDWSTSRLYWVDAFFDKIEHSNLDGLDRKR- 905
Query: 5041 LASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHP 5220
L + HP L +F+D ++ +D RL + + + +G S + V A
Sbjct: 906 LGHVDQMTHPFGLTVFKDNVFLTDWRLGAI-IRVRKSDGGDMTVVRRGISSIMHVKAYDA 964
Query: 5221 VLQPVIKNNPCSTNP---CSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDD 5364
LQ +T+P CSH C C CP G KL C D
Sbjct: 965 DLQTGTNYCSQTTHPNGDCSHFCFPVPNFQRVCGCPYGMKLQRDQMTCEGD 1015
Score = 147 bits (370), Expect = 1e-32
Identities = 147/576 (25%), Positives = 236/576 (40%), Gaps = 71/576 (12%)
Frame = +1
Query: 394 PASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCAD 573
P S +C S N F C +G C S +CDG DC D +DE R+ C F C
Sbjct: 22 PVSGQECGSGN-FRCDNG-YCIPASWRCDGTRDCLDDTDEIGCPPRS---CGSGFFLCPA 76
Query: 574 KTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDN 753
+ CI SWVCD KDC+DG+DE C C++ + C N +C P ++RCD+ DC D
Sbjct: 77 EGTCIPSSWVCDQDKDCSDGADEQQNCPGTTCSSQQLTCSNGQCVPIEYRCDHVSDCPDG 136
Query: 754 SDE-----DECGEYRCPPG--------------------KWNCP----------GTGHCI 828
SDE C + C G + NC G+G CI
Sbjct: 137 SDERNCYYPTCDQLTCANGACYNTSQKCDHKVDCRDSSDEANCTTLCSQKEFQCGSGECI 196
Query: 829 DQLKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTC 1008
+ +CD DC D +DE C+ + C G + TC +G ++ + C
Sbjct: 197 LRAYVCDHDNDCEDNSDEHNCNYDTC-------------GGHQFTCSNGQCINQNW--VC 241
Query: 1009 SDINECAEFGYCDQLCANHRPGFTC-----SCLGDCFTLQME----------HGPGKDNL 1143
++C + G D C +++ TC +C G + M+ G ++N
Sbjct: 242 DGDDDCQDSGDEDG-CESNQRHHTCYPREWACPGSGRCISMDKVCDGVPDCPEGEDENNA 300
Query: 1144 TMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWT 1323
T YC + + + Y P + + S + IDFD D +I+
Sbjct: 301 TSGRYCGTGLCSILNCEYQCHQTPYGGECFCPPGHI--INSNDSRTCIDFD--DCQIWGI 356
Query: 1324 DRLAHSAFSADVDDEGEISQIKKLSLKSLVYPR---CLAVDWITNTLYIIESGSRRIDVS 1494
D E + + L + + R C + D + II S R + V
Sbjct: 357 ---------CDQKCESRQGRHQCLCEEGYILERGQHCKSNDSF-SAASIIFSNGRDLLVG 406
Query: 1495 SYDGERRTVLLAD---GLTLPLDIALDPLRGEMFFTN--QLKLEAAAMDGTNRRTLVNTH 1659
G +L G+ + +D R +F+T+ Q K+ + ++G N + ++N
Sbjct: 407 DLHGRNFRILAESKNRGIVMGVDFHYQKHR--VFWTDPMQAKVFSTDINGLNTQEILNVS 464
Query: 1660 THQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDR-RIVAQGMNVVPHPFGLALFDQ-- 1830
+ VD ++Y V+ +V+R++ ++ +GN R ++ + + HP G+AL
Sbjct: 465 IDAPENLAVDWINNKLYLVETRVNRIDVVNLEGNQRVTLITENLG---HPRGIALDPTVG 521
Query: 1831 YLYWTDWTRL-GVIQVEKFGSD---------TKLLW 1908
YL+++DW L G +VE+ D TKL W
Sbjct: 522 YLFFSDWGSLSGQPKVERAFMDGSNRKDLVTTKLGW 557
Score = 144 bits (362), Expect = 8e-32
Identities = 114/412 (27%), Positives = 164/412 (39%), Gaps = 8/412 (1%)
Frame = +1
Query: 8362 PAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCI 8541
P + C + +G+CI CD DC+D +DE N C +C C+N +C+
Sbjct: 63 PPRSCGSGFFLCPAEGTCIPSSWVCDQDKDCSDGADEQQN-CPGTTCSSQQLTCSNGQCV 121
Query: 8542 DSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDE 8721
+C+H+ DC DGSDE +C C + T C+NG C N ++ CD DC D SDE
Sbjct: 122 PIEYRCDHVSDCPDGSDERNC-YYPTCDQLT--CANGACYNTSQKCDHKVDCRDS--SDE 176
Query: 8722 SLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVR 8901
A C L C + +C + CI A +CD +DC D +DE+ C C H
Sbjct: 177 --ANCTTL---CSQKEFQC-GSGECILRAYVCDHDNDCEDNSDEHN--CNYDTCGGHQFT 228
Query: 8902 CPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXX 9081
C +G+CI + W CDGD+DC D DE C++
Sbjct: 229 CSNGQCINQNWVCDGDDDCQDSGDED-------------------GCES----------- 258
Query: 9082 XXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGED 9261
+ RH TC +E+ C + + CI +CDG C GED
Sbjct: 259 -----------NQRH----HTCYPREWACPGSGR-------CISMDKVCDGVPDCPEGED 296
Query: 9262 ESTELCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQC 9441
E+ T + C G CS +C + + +C N S DF C
Sbjct: 297 ENN---ATSGRYCGTG--LCSILNCEYQCHQTPYGGECFCPPGHIINSNDSRTCIDFDDC 351
Query: 9442 ANHKCVPNSWKCDGNDD-----CEDG---SDEKDCPKNSASAQKASKCSNGQ 9573
KC+ CE+G + C N + + + SNG+
Sbjct: 352 QIWGICDQ--KCESRQGRHQCLCEEGYILERGQHCKSNDSFSAASIIFSNGR 401
Score = 141 bits (356), Expect = 4e-31
Identities = 101/365 (27%), Positives = 134/365 (36%), Gaps = 46/365 (12%)
Frame = +1
Query: 8836 GDKADENQLFCMN--------QQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNC 8991
G K +Q+ C QQC C +G+C+P ++CD G D+ H N
Sbjct: 1002 GMKLQRDQMTCEGDPAREPPTQQCGSSSFPCNNGKCVPSIFRCD-------GVDDCHDNS 1054
Query: 8992 TDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXXXXXXHSRHGCG--NRTCTDQEFH 9165
+ H CG N TC+ F
Sbjct: 1055 DE------------------------------------------HQCGALNNTCSSSAFT 1072
Query: 9166 CTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECNKGEFRCSNQHCIHS 9345
C +CIP W CD C G DE ++ C F C N CI
Sbjct: 1073 CVHGG-------QCIPGQWRCDKQNDCLDGSDEQNCPTRSPSSTCPPTSFTCDNHMCIPK 1125
Query: 9346 TWECDGDNDCLDGSDEHANCTYS-SCQPDFFQCANHKCVPNSWKCDGNDDCEDGSDEKDC 9522
W CD DNDC DGSDE NC S +C P F+C +H+C+ + CDG+ DC DGSDE C
Sbjct: 1126 EWVCDTDNDCSDGSDEK-NCQASGTCHPTQFRCPDHRCISPLYVCDGDKDCVDGSDEAGC 1184
Query: 9523 PKNSASAQ----KASKCSNGQFQCTS-------------------------------GEC 9597
N S+Q S C N +++C G C
Sbjct: 1185 VLNCTSSQFKCADGSSCINSRYRCDGVYDCKDNSDEAGCPTRPPGMCHPDEFQCQGDGTC 1244
Query: 9598 IDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDIS 9777
I + CD + DC SDE + C CS + C + + CD + D+S
Sbjct: 1245 IPNTWECDGHPDCIQGSDEHNGCVPKTCSPSHFLCDNGNC--IYNSWVCD-GDNDCRDMS 1301
Query: 9778 DQKSC 9792
D+K C
Sbjct: 1302 DEKDC 1306
Score = 133 bits (334), Expect = 1e-28
Identities = 96/306 (31%), Positives = 127/306 (41%), Gaps = 6/306 (1%)
Frame = +1
Query: 3436 CAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLEMCG--NATCAANQFSCANG-RCIPI 3606
C + F C+N +C+P ++ E CG N TC+++ F+C +G +CIP
Sbjct: 1025 CGSSSFPCNNGKCVPSIFRCDGVDDCHDNSDE--HQCGALNNTCSSSAFTCVHGGQCIPG 1082
Query: 3607 YWLCDGDNDCYDGTDEDK--ERCPPVQCSALQFRCANGRQCVPLRNHXXXXXXXXXXXXX 3780
W CD NDC DG+DE R P C F C N C+P +
Sbjct: 1083 QWRCDKQNDCLDGSDEQNCPTRSPSSTCPPTSFTCDN-HMCIP-KEWVCDTDNDCSDGSD 1140
Query: 3781 XXXAVTAESCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKC 3960
+ +C P QF+C CI + SDE GC C+S QFKC
Sbjct: 1141 EKNCQASGTCHPTQFRCPDHR-CISPLYVCDGDKDCVDGSDEA--GCVLN--CTSSQFKC 1195
Query: 3961 GNGR-CILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQL 4137
+G CI + + CDG DC D SDE+ GC T C + C+ D TCIP
Sbjct: 1196 ADGSSCINSRYRCDGVYDCKDNSDEA---GCPTRPPGM-CHPDEFQCQGDG-TCIPNTWE 1250
Query: 4138 CDGKTHCPGGTDEGGRCARDLCSADRAGCSFKCHNSPNGPICSCPFGEQLVNKTKCEPEN 4317
CDG C G+DE C CS F C N G + N C+ +N
Sbjct: 1251 CDGHPDCIQGSDEHNGCVPKTCSPSH----FLCDN-----------GNCIYNSWVCDGDN 1295
Query: 4318 ECLDSS 4335
+C D S
Sbjct: 1296 DCRDMS 1301
Score = 126 bits (317), Expect = 1e-26
Identities = 77/224 (34%), Positives = 109/224 (48%), Gaps = 10/224 (4%)
Frame = +1
Query: 9274 LCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQC-ANH 9450
L +EC G FRC N +CI ++W CDG DCLD +DE C SC FF C A
Sbjct: 20 LAPVSGQECGSGNFRCDNGYCIPASWRCDGTRDCLDDTDE-IGCPPRSCGSGFFLCPAEG 78
Query: 9451 KCVPNSWKCDGNDDCEDGSDE-KDCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRN 9627
C+P+SW CD + DC DG+DE ++CP + CS+ Q C++G+C+ CD
Sbjct: 79 TCIPSSWVCDQDKDCSDGADEQQNCP--------GTTCSSQQLTCSNGQCVPIEYRCDHV 130
Query: 9628 FDCTDRSDESSLCFIDECSLAEKPLCEQKCMD--MKIGYKCDCFEGFAIDISDQKSCHNV 9801
DC D SDE + C+ C + C + K +K DC D SD+ +C +
Sbjct: 131 SDCPDGSDERN-CYYPTCD--QLTCANGACYNTSQKCDHKVDC-----RDSSDEANCTTL 182
Query: 9802 NECYEGISGCSQK---CDDK---IGSYKCGCVDGYQLSSDDHSC 9915
CSQK C + +Y C + + +SD+H+C
Sbjct: 183 ---------CSQKEFQCGSGECILRAYVCDHDNDCEDNSDEHNC 217
Score = 119 bits (299), Expect = 2e-24
Identities = 95/354 (26%), Positives = 132/354 (36%), Gaps = 4/354 (1%)
Frame = +1
Query: 10738 PAYPNPCGDNNGGCSH-LCLIGAGGNGYTCSCPDQFVLLSDQKTCEP-NCTERQFACGGD 10911
P CG N C + C+ + T C D +D+ C P +C F C +
Sbjct: 22 PVSGQECGSGNFRCDNGYCIPASWRCDGTRDCLDD----TDEIGCPPRSCGSGFFLCPAE 77
Query: 10912 DAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXX 11091
CIP W CD + DC DG+DE + C C + C+N C
Sbjct: 78 GT-CIPSSWVCDQDKDCSDGADE--QQNCPGTTCSSQQLTCSNGQCVPIEYRCDHVSDCP 134
Query: 11092 XXXXEQNC-DKACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEADTLCMSAERNCTAE 11268
E+NC CD C A G C SDEA+ + C+ +
Sbjct: 135 DGSDERNCYYPTCD--QLTC-ANGACYNTSQKCDHKVDCRDSSDEANCTTL-----CSQK 186
Query: 11269 EFRCNNNKCIAKAWRXXXXXXXXXXXXETPECAQIECKKGWTRCSSSYRCIPNWAFCNGQ 11448
EF+C + +CI +A+ C+
Sbjct: 187 EFQCGSGECILRAY-----------------------------------------VCDHD 205
Query: 11449 DDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTR 11628
+DC DNSDE TC +F C ++G+CI + W+CD ++DC D+ DE
Sbjct: 206 NDCEDNSDEHNCNYDTCGG-HQFTC-SNGQCINQNWVCDGDDDCQDSGDEDGCESNQRHH 263
Query: 11629 PCSESEFRC-NDGKCIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQCDDGTC 11787
C E+ C G+CI KVCDG C +G DE+ T R C G C
Sbjct: 264 TCYPREWACPGSGRCISMDKVCDGVPDCPEGEDENNAT------SGRYCGTGLC 311
Score = 117 bits (294), Expect = 6e-24
Identities = 68/210 (32%), Positives = 99/210 (46%), Gaps = 2/210 (0%)
Frame = +1
Query: 9292 KECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEH-ANCTYSSCQPDFFQCANH-KCVPN 9465
++C F C+N C+ S + CDG +DC D SDEH ++C F C + +C+P
Sbjct: 1023 QQCGSSSFPCNNGKCVPSIFRCDGVDDCHDNSDEHQCGALNNTCSSSAFTCVHGGQCIPG 1082
Query: 9466 SWKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDR 9645
W+CD +DC DGSDE++CP S S S C F C + CI VCD + DC+D
Sbjct: 1083 QWRCDKQNDCLDGSDEQNCPTRSPS----STCPPTSFTCDNHMCIPKEWVCDTDNDCSDG 1138
Query: 9646 SDESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNECYEGIS 9825
SDE + C + + +C+ Y CD + +D SD+ C V C
Sbjct: 1139 SDEKNCQASGTCHPTQFRCPDHRCISPL--YVCD-GDKDCVDGSDEAGC--VLNCTSSQF 1193
Query: 9826 GCSQKCDDKIGSYKCGCVDGYQLSSDDHSC 9915
C+ Y+C V + +SD+ C
Sbjct: 1194 KCADGSSCINSRYRCDGVYDCKDNSDEAGC 1223
Score = 83.2 bits (204), Expect = 2e-13
Identities = 59/202 (29%), Positives = 83/202 (40%), Gaps = 35/202 (17%)
Frame = +1
Query: 3925 SGRQCSSDQFKCGNGRCILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACEN 4104
SG++C S F+C NG CI +W CDG DC D +DE GC R C C
Sbjct: 24 SGQECGSGNFRCDNGYCIPASWRCDGTRDCLDDTDEI---GCP----PRSCGSGFFLCP- 75
Query: 4105 DQETCIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCS--------FKC---HNSPN 4251
+ TCIP +CD C G DE C CS+ + CS ++C + P+
Sbjct: 76 AEGTCIPSSWVCDQDKDCSDGADEQQNCPGTTCSSQQLTCSNGQCVPIEYRCDHVSDCPD 135
Query: 4252 G--------PIC---SCPFGEQLVNKTKCEPENECLDSS---SCSQRCKDEK-------- 4365
G P C +C G KC+ + +C DSS +C+ C ++
Sbjct: 136 GSDERNCYYPTCDQLTCANGACYNTSQKCDHKVDCRDSSDEANCTTLCSQKEFQCGSGEC 195
Query: 4366 --HGFTCSCDEGYELDVDKRTC 4425
+ C D E + D+ C
Sbjct: 196 ILRAYVCDHDNDCEDNSDEHNC 217
Score = 81.6 bits (200), Expect = 5e-13
Identities = 63/247 (25%), Positives = 110/247 (44%), Gaps = 16/247 (6%)
Frame = +1
Query: 12967 KKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAI 13146
++ + +L P +++ P+AG + SD AKI A DG+H IV + P +AI
Sbjct: 817 RRQIISNLNNPRSIVVHPAAGYMFLSDWFRPAKIMRAWSDGSHLMPIVNTSLGWPNGLAI 876
Query: 13147 DEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHI--PYAVDVFENHIYWLSRESKTL 13320
D +R+YWVD + +++ N+DG +R + H + P+ + VF+++++ +
Sbjct: 877 D-WSTSRLYWVDAFFDKIEHSNLDGLDRKRLGHVDQMTHPFGLTVFKDNVFLTDWRLGAI 935
Query: 13321 YVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCER-----AQCSHLCVSLPS 13485
K G ++V+ + ++ + Y D Q + C + CSH C +P+
Sbjct: 936 IRVRKSDGGDMTVVRRGIS---SIMHVKAYDADLQTGTNYCSQTTHPNGDCSHFCFPVPN 992
Query: 13486 TGFACLCPDGIVPQLDGSCATQHVEALTMPKQCKCT----NGGKC-----RLDGSCECTS 13638
C CP G+ Q D +QC + N GKC R DG +C
Sbjct: 993 FQRVCGCPYGMKLQRDQMTCEGDPAREPPTQQCGSSSFPCNNGKCVPSIFRCDGVDDCHD 1052
Query: 13639 DFEGDQC 13659
+ + QC
Sbjct: 1053 NSDEHQC 1059
Score = 68.2 bits (165), Expect = 6e-09
Identities = 65/233 (27%), Positives = 89/233 (37%), Gaps = 19/233 (8%)
Frame = +1
Query: 11839 DELHCE-DVSR----RTCSPFEFECANSVCIPRKFMXXXXXXXXXXSDETSSECRSAQCD 12003
D++ CE D +R + C F C N C+P F SDE + C
Sbjct: 1008 DQMTCEGDPAREPPTQQCGSSSFPCNNGKCVPSIFRCDGVDDCHDNSDEHQCGALNNTCS 1067
Query: 12004 PPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSFSEYGDCSSDQFKCANGKC 12183
F C H C+ C+ NDC D SDE C + S C F C N C
Sbjct: 1068 SSA-FTCVHGGQCIPGQWRCDKQNDC--LDGSDEQ--NCPTRSPSSTCPPTSFTCDNHMC 1122
Query: 12184 VNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKHICTDVRDGFYCHCRDGFR 12363
+ CD +DC D SDE +C+A G + C D R + DG
Sbjct: 1123 IPKEWVCDTDNDCSDGSDE---------KNCQASGTCHPTQFRCPDHRCISPLYVCDG-- 1171
Query: 12364 PDPQSPKECIDIDECAG---NNTCTQL-------CLNTK----GSYLCRCHED 12480
K+C+D + AG N T +Q C+N++ G Y C+ + D
Sbjct: 1172 -----DKDCVDGSDEAGCVLNCTSSQFKCADGSSCINSRYRCDGVYDCKDNSD 1219
Score = 65.1 bits (157), Expect = 5e-08
Identities = 59/246 (23%), Positives = 92/246 (36%), Gaps = 35/246 (14%)
Frame = +1
Query: 11860 VSRRTCSPFEFECANSVCIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRL 12039
VS + C F C N CIP + +DE C C F C
Sbjct: 23 VSGQECGSGNFRCDNGYCIPASWRCDGTRDCLDDTDEIG--CPPRSCGSGF-FLCPAEGT 79
Query: 12040 CLNILQLCNGFNDCG---------------------------PNDFSDEHLSMCSSFSEY 12138
C+ +C+ DC P ++ +H+S C S+
Sbjct: 80 CIPSSWVCDQDKDCSDGADEQQNCPGTTCSSQQLTCSNGQCVPIEYRCDHVSDCPDGSDE 139
Query: 12139 GDC---SSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGC-- 12303
+C + DQ CANG C N + CD K DC D+SDE C+ + + +G C
Sbjct: 140 RNCYYPTCDQLTCANGACYNTSQKCDHKVDCRDSSDEANCTTLCSQKEFQC--GSGECIL 197
Query: 12304 -KHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNN-TCTQ-LCLNTKGSYLCRCH 12474
++C D C D S + + D C G+ TC+ C+N +++C
Sbjct: 198 RAYVCDHDND-----CED------NSDEHNCNYDTCGGHQFTCSNGQCINQ--NWVCDGD 244
Query: 12475 EDYENN 12492
+D +++
Sbjct: 245 DDCQDS 250
Score = 62.8 bits (151), Expect = 2e-07
Identities = 64/271 (23%), Positives = 94/271 (34%), Gaps = 11/271 (4%)
Frame = +1
Query: 8182 TSQLC--------KTDNGGCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQC 8337
TSQ C +D C LC S+ + C +++ D+ C
Sbjct: 160 TSQKCDHKVDCRDSSDEANCTTLC-----------SQKEFQCGSGECILRAYVCDHDNDC 208
Query: 8338 VLRGSNSEPAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTR--SC-PE 8508
+ + F C +G CI CD DC D+ DE+ N R +C P
Sbjct: 209 EDNSDEHNCNYDTCGGHQFTCSNGQCINQNWVCDGDDDCQDSGDEDGCESNQRHHTCYPR 268
Query: 8509 DYNLCTNRRCIDSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGH 8688
++ + RCI K C+ + DC +G DE + S C GT CS +C Q
Sbjct: 269 EWACPGSGRCISMDKVCDGVPDCPEGEDENNATSGRYC--GTGLCSILNCEYQ------- 319
Query: 8689 NDCHDEQVSDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFC 8868
CH E CP G + ++ CI D C + C K + Q
Sbjct: 320 --CHQTPYGGECF--CP------PGHIINSNDSRTCID-FDDCQIWGICDQKCESRQ--- 365
Query: 8869 MNQQCAQHYVRCPSGRCIPETWQCDGDNDCS 8961
+H C G + C ++ S
Sbjct: 366 -----GRHQCLCEEGYILERGQHCKSNDSFS 391
Score = 47.8 bits (112), Expect = 0.008
Identities = 43/133 (32%), Positives = 55/133 (41%), Gaps = 2/133 (1%)
Frame = +1
Query: 12145 CSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKHICTDV 12324
C S F C NGKCV CD DDC D SDE C S AF G + I
Sbjct: 1025 CGSSSFPCNNGKCVPSIFRCDGVDDCHDNSDEHQCGALNNTCSSSAFTCVHGGQCIPGQW 1084
Query: 12325 RDGFYCHCRDGFRPDPQSPKECIDIDECAGNN-TC-TQLCLNTKGSYLCRCHEDYENNVV 12498
R C DG D Q+ C + TC +C+ + ++C D +N+
Sbjct: 1085 RCDKQNDCLDG--SDEQNCPTRSPSSTCPPTSFTCDNHMCIPKE--WVC----DTDNDCS 1136
Query: 12499 VGSMTGKDCRAKG 12537
GS K+C+A G
Sbjct: 1137 DGS-DEKNCQASG 1148
>gi|3170549|gb|AAC34396.1| LRP1 [Takifugu rubripes]
Length = 1581
Score = 751 bits (1939), Expect = 0.0
Identities = 453/1348 (33%), Positives = 667/1348 (48%), Gaps = 41/1348 (3%)
Frame = +1
Query: 9742 CDCFEGFAIDISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHS-CK 9918
C C GF + D ++C +++EC CSQ+C + GS+ C CVDG++LS +D + CK
Sbjct: 1 CRCHPGFQLK-RDGRTCVDIDECTTTYP-CSQRCINTHGSFHCLCVDGFELSPNDPTICK 58
Query: 9919 RTEMEPEPFFLLANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLID---QGK 10089
R + + AN++Y+RK+++DG+ Y L QG +N V+LD E+ Y D QG
Sbjct: 59 R-----RTYLIFANRYYLRKLNLDGSNYTLIKQGLNNAVALDFHYAEQMIYWTDVTTQGS 113
Query: 10090 LRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRF 10269
+ + M SS E + R ++ +G+AVDWVG LY ++ +I V +L+G +
Sbjct: 114 M------IRRMRMNGSSMEVLHRTSLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLNGAY 167
Query: 10270 CKTLIRDRIQQPKAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGW 10449
L+ +++P+A+ V GYL++++W P+IGRI +DG+ + E + W
Sbjct: 168 RTVLVNSGLREPRALAVDVRYGYLYWSDWGDSPHIGRIGMDGTNRSV-----IVEEKITW 222
Query: 10450 PNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWN 10629
PN + +D+ +DR++W DA + I F DG R + H+ +M +F++Y+YW DW
Sbjct: 223 PNGLTLDFINDRIYWADAREDYIEFASLDGTNRHTVLNHDIPHIFAMTLFEEYIYWTDWE 282
Query: 10630 LREVLRCDKWTGKNETILKKTVQLPNDLRIVHPMRQPAYPN-PCGDNNGGCSHLCLIGAG 10806
+ + R K G N+T L T+ P D+ I HP RQP N PC NNGGCS+LCL+ G
Sbjct: 283 TKSINRAHKTQGTNKTTLISTLHRPMDVHIYHPYRQPEVLNHPCQTNNGGCSNLCLLSPG 342
Query: 10807 GNGYTCSCPDQFVLLSDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPG 10986
G GY C+CP F L SD +TC NCT QF C D KCIP W CD E DC D SDEP
Sbjct: 343 G-GYKCACPTNFYLASDHRTCMSNCTASQFVCKND--KCIPFWWKCDTEDDCGDRSDEPA 399
Query: 10987 ESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXXEQNCD-KACDPWMFKCAATGR 11163
+ C + C G+FQC CT P I E NCD C P FKC+ R
Sbjct: 400 D--CPEFKCRPGQFQCGTGICTNPAYICDGDNDCQDNSDEANCDIHVCLPSQFKCSHPSR 457
Query: 11164 CIPRRFTXXXXXXXXXRSDEADTLCMSAERNCTAEEFRCN-NNKCIAKAWRXXXXXXXXX 11340
CIP F DE D E C +F+C +CI + W
Sbjct: 458 CIPGIFRCNGQDNCGDGEDEKD----CPEVTCAPTQFQCAITKRCIPRVWVCDRDNDCVD 513
Query: 11341 XXXETPECAQIECKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCP--TCDDVGE 11514
E C Q+ C RC S RCIP C+G+DDC D SDE K+ C TC+ +
Sbjct: 514 GSDEPANCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDASDEPKEECAERTCEPY-Q 572
Query: 11515 FRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCD 11694
FRC + +C+P RW CD +NDCGDNSDE C R CSESEF C +G+CI G CD
Sbjct: 573 FRC-KNNRCVPGRWQCDYDNDCGDNSDE--DKC--MPRQCSESEFACTNGRCIAGRWKCD 627
Query: 11695 GTIQCSDGLDESQCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRT 11874
G C+DG DE C L +C H QC++G CI CD DC + +DE +C + R
Sbjct: 628 GDHDCADGSDEHGCDL-KCDIDHFQCNNGHCIPIRWRCDADPDCLDGSDEENCG--TERH 684
Query: 11875 CSPFEFECANSVCIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNIL 12054
C EF+C N++C P + SDE ECR QC P FRC + R+CL +
Sbjct: 685 CPVDEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEECRKFQCPPTRAFRCQNDRVCLQVS 744
Query: 12055 QLCNGFNDCGPNDFSDEHLSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGD-A 12231
+ C+G ++CG N SDE C C D+F CAN +C++ T+ C+ +DC D
Sbjct: 745 KRCDGVSNCGDN--SDE--LNCQIPPAIPTCEKDEFLCANNRCISSTLRCNFFNDCEDFG 800
Query: 12232 SDEIGCSKHGGKTSCEAFG---NNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDID 12402
SDEIGC T C + +G H T+ D F C C+ GF+ + C D +
Sbjct: 801 SDEIGCKTDTKLTDCRSNRTQCGDGDEAHCVTNGTDSF-CSCKAGFQ--KIGHRTCGDKN 857
Query: 12403 ECAGNNTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAK--GDAANVMIGADDSL 12576
EC C+ +C NTKGSY C CH+ + + C+A + ++ ADD+
Sbjct: 858 ECLQFGVCSHICNNTKGSYKCSCHKYF-------TRISDTCKADNINSSRQILYIADDNE 910
Query: 12577 VQLSLHGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERTIYR------SAIAN 12738
++ G R+ + ++W + I S A
Sbjct: 911 IRSLDPGMPDWRYEQTFQGDASVRIDAMDVHVKTNRIFWTNWHTGRISTYELQGPSLSAT 970
Query: 12739 GNQSH------EGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRM 12900
+ SH EG+ +D+ + +P IAVD+ GNL+ ++
Sbjct: 971 SSNSHRNRRQSEGRVIDLQIKEL-KMPRGIAVDWVAGNLYWTDSGRDV------------ 1017
Query: 12901 SEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECAD 13080
I V G++ K +++G + +P A++ P G + ++D G H KIE A
Sbjct: 1018 -----------IEVAQMSGQHCKTLISGMIDEPYAIVVDPQRGTMYWADWGNHPKIETAA 1066
Query: 13081 MDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVV----HD 13248
MDGT RQ +V + + PT +A+D R+YW D K + +V +DGS+ V ++
Sbjct: 1067 MDGTLRQTLVHENIQWPTGLAVDY-YNERLYWADAKLSVIGSVRLDGSDPVIAVSGIKNN 1125
Query: 13249 RHIPYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQR 13428
P+++D+FE++IY ++ + ++ +KFG+G + L + + + + +Y K +
Sbjct: 1126 LLHPFSIDIFEDYIYGVTYINNIVFRVNKFGKGTMENLTTGINHASDIVLHHRY-KQPEM 1184
Query: 13429 TVSGCERAQCSHLCVSLPSTGFACLCPDGIVPQLDGSCATQ------HVEALTMPKQCKC 13590
T + C+R +C LC+ PS G C CP+ V +G+C + + P +C
Sbjct: 1185 T-NPCDRKKCEWLCLLSPS-GPVCTCPNKYVAD-NGTCVERPKPTQSPFSPPSEPCDIQC 1241
Query: 13591 TNGGKCRLD----GSCECTSDFEGDQCE 13662
NGG C L+ C C + GD+C+
Sbjct: 1242 LNGGSCFLNARQVAKCRCQPSYIGDRCD 1269
Score = 449 bits (1156), Expect = e-124
Identities = 367/1319 (27%), Positives = 545/1319 (40%), Gaps = 86/1319 (6%)
Frame = +1
Query: 7228 PCTQLCFATPGTQTPTCSCARGVL---KGRTCEEPDTYIMFSDGDKIIDVAIEPDVKASR 7398
PC+Q C T G+ C C G T + TY++F++ + + + D
Sbjct: 27 PCSQRCINTHGSFH--CLCVDGFELSPNDPTICKRRTYLIFANRYYLRKLNL--DGSNYT 82
Query: 7399 PLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAENPRLVFGASKQPHAK 7578
+K ++N D + +Y+ + G I MN + L H
Sbjct: 83 LIKQG---LNNAVALDFHYAEQMIYWTDVTTQGSMIRRMRMNGSSMEVL--------HRT 131
Query: 7579 EIRHISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTIASGDWTY--ALAIDPCSGLL 7752
+ + + +DW+ +Y+ + G + + + + ALA+D G L
Sbjct: 132 SLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVNSGLREPRALAVDVRYGYL 191
Query: 7753 FWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVDFRNQKIYWADVNRLN 7932
+WSD G P I R + G +R VIV E I+ P + +DF N +IYWAD
Sbjct: 192 YWSDWGDS-------PHIGRIGMDGTNRSVIVEEKITWPNGLTLDFINDRIYWADAREDY 244
Query: 7933 IEVADYDGQNRKVIASGY--RAKSLDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVSDR 8106
IE A DG NR + + ++ +++ ++Y +D + + R K G+ ++S
Sbjct: 245 IEFASLDGTNRHTVLNHDIPHIFAMTLFEEYIYWTDWETKSINRAHKTQGTNKTTLISTL 304
Query: 8107 RIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLCTVVADDIGLAASKVQCSCN 8286
P + ++ N C +T+NGGC LC + +C+C
Sbjct: 305 HRPMDVHIYHPYRQPEVLNHPC--------QTNNGGCSNLCLLSP------GGGYKCAC- 349
Query: 8287 DTYELVQEPGKDYPTQCVLRGSNSEPAKECLPPYNFQCGDGSCILLGATCDSKPDCADAS 8466
PT L + C F C + CI CD++ DC D S
Sbjct: 350 -------------PTNFYLASDHRTCMSNCTAS-QFVCKNDKCIPFWWKCDTEDDCGDRS 395
Query: 8467 DENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCS 8646
DE P C C C C + A C+ +DC D SDE +C V C F CS
Sbjct: 396 DE-PADCPEFKCRPGQFQCGTGICTNPAYICDGDNDCQDNSDEANCDIHV-CLPSQFKCS 453
Query: 8647 N-GHCINQTKVCDGHNDCHDEQVSDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDG 8823
+ CI C+G ++C D + DE CP + C + +C T CI +CD
Sbjct: 454 HPSRCIPGIFRCNGQDNCGDGE--DEK--DCP--EVTCAPTQFQCAITKRCIPRVWVCDR 507
Query: 8824 YDDCGDKADENQLFCMNQQCAQHYVRCP-SGRCIPETWQCDGDNDCSDGWDETHTNCTDT 9000
+DC D +DE C C RC SGRCIP W+CDG++DC D DE C +
Sbjct: 508 DNDCVDGSDE-PANCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDASDEPKEECAER 566
Query: 9001 AGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNA 9180
+ Y F+C N +C+ + C R C++ EF CT+
Sbjct: 567 TCEP-----YQFRCKNNRCVPGRW---QCDYDNDCGDNSDEDKCMPRQCSESEFACTNG- 617
Query: 9181 KLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECNKGEFRCSNQHCIHSTWECD 9360
CI W CDGD CA G DE C + C+ F+C+N HCI W CD
Sbjct: 618 -------RCIAGRWKCDGDHDCADGSDEHG--CDLK---CDIDHFQCNNGHCIPIRWRCD 665
Query: 9361 GDNDCLDGSDEHANCTYSSCQPDFFQCANHKCVPNSWKCDGNDDCEDGSDE--KDCPKNS 9534
D DCLDGSDE T C D FQC N C P +WKCDG DDC D SDE ++C K
Sbjct: 666 ADPDCLDGSDEENCGTERHCPVDEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEECRKFQ 725
Query: 9535 ASAQKASKCSN-------------------------------------GQFQCTSGECID 9603
+A +C N +F C + CI
Sbjct: 726 CPPTRAFRCQNDRVCLQVSKRCDGVSNCGDNSDELNCQIPPAIPTCEKDEFLCANNRCIS 785
Query: 9604 DAKVCDRNFDCTDRSDESSLCFID----ECSLAEKPLC----EQKCMDMKIGYKCDCFEG 9759
C+ DC D + C D +C + + C E C+ C C G
Sbjct: 786 STLRCNFFNDCEDFGSDEIGCKTDTKLTDCR-SNRTQCGDGDEAHCVTNGTDSFCSCKAG 844
Query: 9760 FAIDISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPE 9939
F ++C + NEC + CS C++ GSYKC C + SD +CK +
Sbjct: 845 F--QKIGHRTCGDKNECLQ-FGVCSHICNNTKGSYKCSCHKYFTRISD--TCKADNINSS 899
Query: 9940 PFFL-LANKHYIRKI--SIDGNKYELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVD 10110
L +A+ + IR + + +YE QG D V +D K I R+
Sbjct: 900 RQILYIADDNEIRSLDPGMPDWRYEQTFQG-DASVRIDAMDVHVKTNRIFWTNWHTGRIS 958
Query: 10111 LDEMDSP-LSSYETVLRHNVYGTE---------------GIAVDWVGRKLYMLNRQERSI 10242
E+ P LS+ + N +E GIAVDWV LY + I
Sbjct: 959 TYELQGPSLSATSSNSHRNRRQSEGRVIDLQIKELKMPRGIAVDWVAGNLYWTDSGRDVI 1018
Query: 10243 RVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIF 10422
V ++ G+ CKTLI I +P AIVV P +G +++ +W P I A+DG+
Sbjct: 1019 EVAQMSGQHCKTLISGMIDEPYAIVVDPQRGTMYWADWGNHPKIETAAMDGTLRQ----- 1073
Query: 10423 KLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHIPAQRTS-------HV 10581
L ++ WP +A+DY+++RL+W DA L+ IG + DG+ P S H
Sbjct: 1074 TLVHENIQWPTGLAVDYYNERLYWADAKLSVIGSVRLDGSD----PVIAVSGIKNNLLHP 1129
Query: 10582 SSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDLRIVHPMRQPAYPNPCG 10761
S+ +F+DY+Y + V R +K+ L + +D+ + H +QP NPC
Sbjct: 1130 FSIDIFEDYIYGVTYINNIVFRVNKFGKGTMENLTTGINHASDIVLHHRYKQPEMTNPC- 1188
Query: 10762 DNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTC--EPNCTERQFACGGD--DAKCI 10926
+ C LCL+ +G C+CP+++V +D TC P T+ F+ + D +C+
Sbjct: 1189 -DRKKCEWLCLLSP--SGPVCTCPNKYV--ADNGTCVERPKPTQSPFSPPSEPCDIQCL 1242
Score = 423 bits (1087), Expect = e-116
Identities = 360/1297 (27%), Positives = 521/1297 (39%), Gaps = 174/1297 (13%)
Frame = +1
Query: 2005 IENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLV-NGKRCIDSIDYLLFSSNKIVR 2181
I+ T C CI +G F C C G +L N YL+F++ +R
Sbjct: 19 IDECTTTYPCSQRCI--NTHGSF----HCLCVDGFELSPNDPTICKRRTYLIFANRYYLR 72
Query: 2182 GIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVH--GNSFFYADI--MDNTIYRIRP 2349
+ + + L + G+ V D H ++ D+ + I R+R
Sbjct: 73 KLNLDGSNYTLIKQ------------GLNNAVALDFHYAEQMIYWTDVTTQGSMIRRMRM 120
Query: 2350 DGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLI 2529
+G + T ++ DW+ LY+ D R+++EV K+ R L+
Sbjct: 121 NGSSMEVLHRTSLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLNGA--------YRTVLV 172
Query: 2530 TE-LRDPVSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAE 2706
LR+P ++ V G L++++ I R +DG N VI + P+ + +DF
Sbjct: 173 NSGLREPRALAVDVRYGYLYWSDWGDSPHIGRIGMDGTNRSVIVEEKITWPNGLTLDFIN 232
Query: 2707 NRLCWGDTLLKTISCMDFDGKNV-VKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKK 2883
+R+ W D I DG N L+ D P A+T+ EYIY+ SI R HK
Sbjct: 233 DRIYWADAREDYIEFASLDGTNRHTVLNHDIPHIFAMTLFEEYIYWTDWETKSINRAHKT 292
Query: 2884 NGGGSKIVREFGADERSIFSLKACSHQNQPIPD-DSREHPCRASQ--CTQLCFATPSESH 3054
G + S H P + HPC+ + C+ LC +P +
Sbjct: 293 QGTNKTTLI-------STLHRPMDVHIYHPYRQPEVLNHPCQTNNGGCSNLCLLSPGGGY 345
Query: 3055 PNELEAKCACRQGFMINKENNHSCQKDPAEKIEQLCSSNST--QFQCKNGRCIPKEWKCD 3228
KCAC F + ++ + C SN T QF CKN +CIP WKCD
Sbjct: 346 ------KCACPTNFYLASDH-------------RTCMSNCTASQFVCKNDKCIPFWWKCD 386
Query: 3229 ----------------------------------------GENDCLDESDEID------- 3267
G+NDC D SDE +
Sbjct: 387 TEDDCGDRSDEPADCPEFKCRPGQFQCGTGICTNPAYICDGDNDCQDNSDEANCDIHVCL 446
Query: 3268 EKGDKCFH---------------------------ETECAENTIKCRNTKKCIPAQXXXX 3366
KC H E CA +C TK+CIP
Sbjct: 447 PSQFKCSHPSRCIPGIFRCNGQDNCGDGEDEKDCPEVTCAPTQFQCAITKRCIPRVWVCD 506
Query: 3367 XXXXXXXXXXXXVKYCKDGQ-------KPVCAAKKFQC-DNHRCIPEQWKXXXXXXXXXX 3522
C DG + C +F+C D+ RCIP +WK
Sbjct: 507 RDND-----------CVDGSDEPANCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDA 555
Query: 3523 XXEKLEMCGNATCAANQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFR 3702
E E C TC QF C N RC+P W CD DNDC D +DEDK C P QCS +F
Sbjct: 556 SDEPKEECAERTCEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDEDK--CMPRQCSESEFA 613
Query: 3703 CANGRQCVPLRNHXXXXXXXXXXXXXXXXAVTAESCTPDQFKCVSSGLCIPASWKXXXXX 3882
C NGR C+ R + C D F+C ++G CIP W+
Sbjct: 614 CTNGR-CIAGRWKCDGDHDCADGSDEHGCDL---KCDIDHFQC-NNGHCIPIRWRCDADP 668
Query: 3883 XXXXXSDEPKFGCTSGRQCSSDQFKCGNGRCILNNWLCDGENDCGDGSDESSERGCKTSM 4062
SDE C + R C D+F+C N C W CDGE+DCGD SDE+ E K
Sbjct: 669 DCLDGSDEEN--CGTERHCPVDEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEECRKFQC 726
Query: 4063 NARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGG---------------RCARD 4197
P C+ND+ C+ + + CDG ++C +DE CA +
Sbjct: 727 P----PTRAFRCQNDR-VCLQVSKRCDGVSNCGDNSDELNCQIPPAIPTCEKDEFLCANN 781
Query: 4198 LCSADRAGCSF----------------------------------KCHNSPNGP--ICSC 4269
C + C+F + H NG CSC
Sbjct: 782 RCISSTLRCNFFNDCEDFGSDEIGCKTDTKLTDCRSNRTQCGDGDEAHCVTNGTDSFCSC 841
Query: 4270 PFGEQLVNKTKCEPENECLDSSSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKD 4449
G Q + C +NECL CS C + K + CSC + + D TCK ADN+
Sbjct: 842 KAGFQKIGHRTCGDKNECLQFGVCSHICNNTKGSYKCSCHKYFTRISD--TCK-ADNINS 898
Query: 4450 TR--IYVSNRNRIYYSDHKLDNWHTFGAIVENAIALAWDSL-----TDRIYWSDIREKKI 4608
+R +Y+++ N I D + +W + + ++ D++ T+RI+W++ +I
Sbjct: 899 SRQILYIADDNEIRSLDPGMPDWR-YEQTFQGDASVRIDAMDVHVKTNRIFWTNWHTGRI 957
Query: 4609 ---------LSANRNGTNATVFIADG---------LDITEGIALDWVGRNLYWVDSSLNT 4734
LSA + ++ ++G L + GIA+DWV NLYW DS +
Sbjct: 958 STYELQGPSLSATSSNSHRNRRQSEGRVIDLQIKELKMPRGIAVDWVAGNLYWTDSGRDV 1017
Query: 4735 IEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQNPCIERASMDGTDRQIIV 4914
IEVA + +TL+ + +P I VDP++G M+W DWG +P IE A+MDGT RQ +V
Sbjct: 1018 IEVAQMSGQHCKTLISGM-IDEPYAIVVDPQRGTMYWADWGNHPKIETAAMDGTLRQTLV 1076
Query: 4915 KTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSK-FVQHPHALAIFE 5091
I WP +A+DY +R+Y+AD+KL I V DGS ++ K + HP ++ IFE
Sbjct: 1077 HENIQWPTGLAVDYYNERLYWADAKLSVIGSVRLDGSDPVIAVSGIKNNLLHPFSIDIFE 1136
Query: 5092 DMMY---YSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTN 5262
D +Y Y + + ++ + K T E + + A +V H QP + NPC
Sbjct: 1137 DYIYGVTYINNIVFRVNKFGK----GTMENLTTGINHASDIVLHHRYKQPEM-TNPCDRK 1191
Query: 5263 PCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKP 5373
C LCLL+ C CP K A C++ KP
Sbjct: 1192 KCEWLCLLSPSGP-VCTCP--NKYVADNGTCVERPKP 1225
Score = 304 bits (778), Expect = 5e-80
Identities = 216/751 (28%), Positives = 324/751 (42%), Gaps = 84/751 (11%)
Frame = +1
Query: 139 NTASSVCNENDFRCND-GKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWH 315
N C ++FRC D G+CI W P C + C+ Y +
Sbjct: 520 NCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDASDE---PKEECA--ERTCEPYQFR 574
Query: 316 SVS--CIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKY 489
+ C+ +CD DC D SDE C S++ F C +GR C KCDG +
Sbjct: 575 CKNNRCVPGRWQCDYDNDCGDNSDEDKCMPRQC---SESEFACTNGR-CIAGRWKCDGDH 630
Query: 490 DCRDLSDEKD---SCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEF 660
DC D SDE C +H C + CI W CD DC DGSDE +
Sbjct: 631 DCADGSDEHGCDLKCDIDHFQC--------NNGHCIPIRWRCDADPDCLDGSDEENCGTE 682
Query: 661 KKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDE--DECGEYRCPPGK-WNCPGTGHCID 831
+ C +EFQC N C+P ++CD DDCGDNSDE +EC +++CPP + + C C+
Sbjct: 683 RHCPVDEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEECRKFQCPPTRAFRCQNDRVCLQ 742
Query: 832 QLKLCDGSKDCADGADEQQC----------------SQNLCPS----------------- 912
K CDG +C D +DE C + N C S
Sbjct: 743 VSKRCDGVSNCGDNSDELNCQIPPAIPTCEKDEFLCANNRCISSTLRCNFFNDCEDFGSD 802
Query: 913 -LGC--------------------QAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECA 1029
+GC +A C + C+C +G++ HRTC D NEC
Sbjct: 803 EIGCKTDTKLTDCRSNRTQCGDGDEAHCVTNGTDSFCSCKAGFQKIG--HRTCGDKNECL 860
Query: 1030 EFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARRE 1209
+FG C +C N + + CSC + ++ DN+ N+ + L++A
Sbjct: 861 QFGVCSHICNNTKGSYKCSC--HKYFTRISDTCKADNI---------NSSRQILYIADDN 909
Query: 1210 GLYRLNPKNPDEEVKKLASGEF---IYGIDFDYGDRKIFWTD--------------RLAH 1338
+ L+P PD ++ G+ I +D +IFWT+ L+
Sbjct: 910 EIRSLDPGMPDWRYEQTFQGDASVRIDAMDVHVKTNRIFWTNWHTGRISTYELQGPSLSA 969
Query: 1339 SAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRT 1518
++ ++ + ++ L +K L PR +AVDW+ LY +SG I+V+ G+
Sbjct: 970 TSSNSHRNRRQSEGRVIDLQIKELKMPRGIAVDWVAGNLYWTDSGRDVIEVAQMSGQHCK 1029
Query: 1519 VLLADGLTLPLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVD 1689
L++ + P I +DP RG M++ N K+E AAMDGT R+TLV+ + +G+ VD
Sbjct: 1030 TLISGMIDEPYAIVVDPQRGTMYWADWGNHPKIETAAMDGTLRQTLVHENIQWPTGLAVD 1089
Query: 1690 ITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGM-NVVPHPFGLALFDQYLYWTDWTRLGV 1866
+R+YW D K+ + S+ G+D I G+ N + HPF + +F+ Y+Y + V
Sbjct: 1090 YYNERLYWADAKLSVIGSVRLDGSDPVIAVSGIKNNLLHPFSIDIFEDYIYGVTYINNIV 1149
Query: 1867 IQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMC 2046
+V KFG T + N+ I +H QP ++ NPC CE +C
Sbjct: 1150 FRVNKFGKGTMENLTTGINHA--SDIVLHHRYKQP----------EMTNPCDRKKCEWLC 1197
Query: 2047 ILSKDNGGFGVGYKCACPIGQKLVNGKRCID 2139
+LS G C CP NG C++
Sbjct: 1198 LLSPS------GPVCTCPNKYVADNG-TCVE 1221
Score = 232 bits (591), Expect = 2e-58
Identities = 135/376 (35%), Positives = 200/376 (52%), Gaps = 8/376 (2%)
Frame = +1
Query: 4261 CSCPFGEQLVNKTK-CEPENECLDSSSCSQRCKDEKHGFTCSCDEGYELDVDKRT-CKVA 4434
C C G QL + C +EC + CSQRC + F C C +G+EL + T CK
Sbjct: 1 CRCHPGFQLKRDGRTCVDIDECTTTYPCSQRCINTHGSFHCLCVDGFELSPNDPTICK-- 58
Query: 4435 DNVKDTRIYVSNRNRIYYSDHKLD--NWHTFGAIVENAIALAWDSLTDRIYWSDIREK-- 4602
R Y+ NR Y LD N+ + NA+AL + IYW+D+ +
Sbjct: 59 -----RRTYLIFANRYYLRKLNLDGSNYTLIKQGLNNAVALDFHYAEQMIYWTDVTTQGS 113
Query: 4603 KILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLV 4782
I NG++ V L +G+A+DWVG NLYW D +TIEV+ L RT+LV
Sbjct: 114 MIRRMRMNGSSMEVLHRTSLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLNGA-YRTVLV 172
Query: 4783 HQNVSQPRGIAVDPRKGVMFWTDWGQNPCIERASMDGTDRQIIVKTKIYWPNTIALDYTT 4962
+ + +PR +AVD R G ++W+DWG +P I R MDGT+R +IV+ KI WPN + LD+
Sbjct: 173 NSGLREPRALAVDVRYGYLYWSDWGDSPHIGRIGMDGTNRSVIVEEKITWPNGLTLDFIN 232
Query: 4963 DRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYP 5142
DR+Y+AD++ D+I+F + DG+ R VL + + H A+ +FE+ +Y++D + +
Sbjct: 233 DRIYWADAREDYIEFASLDGTNRHTVL--NHDIPHIFAMTLFEEYIYWTDWETKSINRAH 290
Query: 5143 KYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTN--PCSHLCLLNNKNTFTCKC 5316
K GT T + + V HP QP + N+PC TN CS+LCLL+ + C C
Sbjct: 291 K-TQGTNKTTLISTLHRPMDVHIYHPYRQPEVLNHPCQTNNGGCSNLCLLSPGGGYKCAC 349
Query: 5317 PMGEKLDASGKKCIDD 5364
P L + + C+ +
Sbjct: 350 PTNFYLASDHRTCMSN 365
Score = 177 bits (448), Expect = 9e-42
Identities = 92/246 (37%), Positives = 119/246 (47%), Gaps = 1/246 (0%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAE 336
C F+C G C + C Q++C H CI
Sbjct: 406 CRPGQFQCGTGICTNPAYICDGDNDCQDNSDEANCDIHVCLPSQFKCS----HPSRCIPG 461
Query: 337 YQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEK 516
RC+ +C DG DEKDCP T + F CA ++C CD DC D SDE
Sbjct: 462 IFRCNGQDNCGDGEDEKDCPEVT---CAPTQFQCAITKRCIPRVWVCDRDNDCVDGSDEP 518
Query: 517 DSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEP-DTCEFKKCTANEFQCK 693
+C++ C +FRC D +CI W CDG DC D SDEP + C + C +F+CK
Sbjct: 519 ANCTQ--MTCGVDEFRCKDSGRCIPARWKCDGEDDCGDASDEPKEECAERTCEPYQFRCK 576
Query: 694 NKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADG 873
N RC P +++CDY +DCGDNSDED+C +C ++ C G CI CDG DCADG
Sbjct: 577 NNRCVPGRWQCDYDNDCGDNSDEDKCMPRQCSESEFACT-NGRCIAGRWKCDGDHDCADG 635
Query: 874 ADEQQC 891
+DE C
Sbjct: 636 SDEHGC 641
Score = 173 bits (439), Expect = 1e-40
Identities = 122/396 (30%), Positives = 177/396 (43%), Gaps = 5/396 (1%)
Frame = +1
Query: 958 CTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKD 1137
C C G++L R RTC DI+EC C Q C N F C C+ D F L P
Sbjct: 1 CRCHPGFQLK-RDGRTCVDIDECTTTYPCSQRCINTHGSFHCLCV-DGFELS----PNDP 54
Query: 1138 NLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIF 1317
+ R + L A R L +LN + + K + +DF Y ++ I+
Sbjct: 55 TICKR---------RTYLIFANRYYLRKLNLDGSNYTLIKQGLNNAV-ALDFHYAEQMIY 104
Query: 1318 WTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSS 1497
WTD + + G S ++ L SL P LAVDW+ LY + G I+VS
Sbjct: 105 WTDVTTQGSMIRRMRMNG--SSMEVLHRTSLSNPDGLAVDWVGGNLYWCDKGRDTIEVSK 162
Query: 1498 YDGERRTVLLADGLTLPLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQ 1668
+G RTVL+ GL P +A+D G ++++ + + MDGTNR +V
Sbjct: 163 LNGAYRTVLVNSGLREPRALAVDVRYGYLYWSDWGDSPHIGRIGMDGTNRSVIVEEKITW 222
Query: 1669 VSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTD 1848
+G+ +D R+YW D + D +E G +R V + +PH F + LF++Y+YWTD
Sbjct: 223 PNGLTLDFINDRIYWADAREDYIEFASLDGTNRHTVLN--HDIPHIFAMTLFEEYIYWTD 280
Query: 1849 WTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPC--T 2022
W + + K K +T + PM + YHP QP + +PC
Sbjct: 281 WETKSINRAHKTQGTNKTTLISTLHR--PMDVHIYHPYRQP---------EVLNHPCQTN 329
Query: 2023 NADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGKR 2130
N C +C+LS G GYKCACP L + R
Sbjct: 330 NGGCSNLCLLSP-----GGGYKCACPTNFYLASDHR 360
Score = 142 bits (358), Expect = 2e-31
Identities = 95/305 (31%), Positives = 127/305 (41%), Gaps = 44/305 (14%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDE-KDCPA----------------- 399
C + Q+ C + CI + +CD DC D SDE DCP
Sbjct: 366 CTASQFVCK-----NDKCIPFWWKCDTEDDCGDRSDEPADCPEFKCRPGQFQCGTGICTN 420
Query: 400 ------STVDCSSQ-------------NVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDS 522
DC + F C+ +C +C+G+ +C D DEKD
Sbjct: 421 PAYICDGDNDCQDNSDEANCDIHVCLPSQFKCSHPSRCIPGIFRCNGQDNCGDGEDEKDC 480
Query: 523 CSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNK- 699
C QF+CA +CI + WVCD DC DGSDEP C C +EF+CK+
Sbjct: 481 ---PEVTCAPTQFQCAITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDEFRCKDSG 537
Query: 700 RCQPRKFRCDYYDDCGDNSDE--DECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADG 873
RC P +++CD DDCGD SDE +EC E C P ++ C C+ CD DC D
Sbjct: 538 RCIPARWKCDGEDDCGDASDEPKEECAERTCEPYQFRCK-NNRCVPGRWQCDYDNDCGDN 596
Query: 874 ADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECA----EFGY 1041
+DE +C C E C +G + R+ C ++CA E G
Sbjct: 597 SDEDKCMPRQCSE-------------SEFACTNGRCIAGRW--KCDGDHDCADGSDEHG- 640
Query: 1042 CDQLC 1056
CD C
Sbjct: 641 CDLKC 645
Score = 126 bits (316), Expect = 2e-26
Identities = 87/265 (32%), Positives = 124/265 (45%), Gaps = 12/265 (4%)
Frame = +1
Query: 343 RCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDS 522
+C T+ SD + C ++ C++ F+C + + C KCD + DC D SDE
Sbjct: 346 KCACPTNFYLASDHRTCMSN---CTASQ-FVCKNDK-CIPFWWKCDTEDDCGDRSDEPAD 400
Query: 523 CSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKN-K 699
C C QF+C C +++CDG DC D SDE + C+ C ++F+C +
Sbjct: 401 CPE--FKCRPGQFQCGTGI-CTNPAYICDGDNDCQDNSDEAN-CDIHVCLPSQFKCSHPS 456
Query: 700 RCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGAD 879
RC P FRC+ D+CGD DE +C E C P ++ C T CI ++ +CD DC DG+D
Sbjct: 457 RCIPGIFRCNGQDNCGDGEDEKDCPEVTCAPTQFQCAITKRCIPRVWVCDRDNDCVDGSD 516
Query: 880 EQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDIN-----ECAEFGYC 1044
E C + C G C P+ +K D C D + ECAE C
Sbjct: 517 EPA----NCTQMTCGVDEFRCKDSGRC-IPARWKCDG--EDDCGDASDEPKEECAE-RTC 568
Query: 1045 DQL---CANHR--PG-FTCSCLGDC 1101
+ C N+R PG + C DC
Sbjct: 569 EPYQFRCKNNRCVPGRWQCDYDNDC 593
Score = 125 bits (313), Expect = 4e-26
Identities = 98/323 (30%), Positives = 154/323 (47%), Gaps = 7/323 (2%)
Frame = +1
Query: 6313 CTCANGYV--KDGQTSCKLFDESFVIVATKTKVIGYPIDETQSKGVAMEPIGGLSITGVD 6486
C C +G+ + T CK +++I A + + +D + + G + +D
Sbjct: 41 CLCVDGFELSPNDPTICKR--RTYLIFANRYYLRKLNLDGSNYTLIKQ---GLNNAVALD 95
Query: 6487 YDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINYNMYFINH 6666
+ Y + IY + + I + SS + R S+ + LA+DW+ N+Y+
Sbjct: 96 FHYAEQMIYWTDVTTQGSMIRRMRMNGSSMEVLHRTSLSNPD--GLAVDWVGGNLYWC-- 151
Query: 6667 DAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQRSFLDGSR 6846
D R IEVSKL+G YR +L+ + P ++AVD YLYW+D G P I R +DG+
Sbjct: 152 DKGRDTIEVSKLNGAYRTVLVNSGLREPRALAVDVRYGYLYWSDWGDSPHIGRIGMDGTN 211
Query: 6847 REVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPE--LVRSDIASAAGVA 7020
R VIV I P L +D + IYW+DA+ D I S GT ++ DI +
Sbjct: 212 RSVIVEEKITWPNGLTLDFINDRIYWADAREDYI-EFASLDGTNRHTVLNHDIPHIFAMT 270
Query: 7021 LHGQNMYWTDNRLEKLFRA--TSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRA-S 7191
L + +YWTD + + RA T N+T+L+ ++L DV ++ QP +
Sbjct: 271 LFEEYIYWTDWETKSINRAHKTQGTNKTTLI-------STLHRPMDVHIYHPYRQPEVLN 323
Query: 7192 SPCQITDNLRKSPCTQLCFATPG 7260
PCQ T+N C+ LC +PG
Sbjct: 324 HPCQ-TNN---GGCSNLCLLSPG 342
Score = 123 bits (309), Expect = 1e-25
Identities = 147/624 (23%), Positives = 246/624 (38%), Gaps = 45/624 (7%)
Frame = +1
Query: 7231 CTQLCFATPGTQTPTCSCARGVLK-GRTCEEPDTYIMFSDGDKIIDVAIEPDVKASRPLK 7407
C+ +C T G+ CSC + + TC+ + + +I+ +A + ++++ P
Sbjct: 865 CSHICNNTKGSYK--CSCHKYFTRISDTCKADN----INSSRQILYIADDNEIRSLDP-- 916
Query: 7408 DPFPEISNLQTF-----------DVDVNLRRVYFV--------VESPVGVNISWFSMNNA 7530
P+ QTF DV V R+++ G ++S S N+
Sbjct: 917 -GMPDWRYEQTFQGDASVRIDAMDVHVKTNRIFWTNWHTGRISTYELQGPSLSATSSNSH 975
Query: 7531 ENPRLVFGASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTIASG- 7707
N R G KE++ + +DW+ +Y+T + +G+H T+ SG
Sbjct: 976 RNRRQSEGRVIDLQIKELKMPRGIAVDWVAGNLYWTDSGRDVIEVAQMSGQHCKTLISGM 1035
Query: 7708 -DWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAV 7884
D YA+ +DP G ++W+D G P+IE + + G R+ +V E+I P +AV
Sbjct: 1036 IDEPYAIVVDPQRGTMYWADWGN-------HPKIETAAMDGTLRQTLVHENIQWPTGLAV 1088
Query: 7885 DFRNQKIYWADVNRLNIEVADYDGQNRKVIASGYRAK-----SLDIWDRWLYMSDPLSNG 8049
D+ N+++YWAD I DG + + SG + S+DI++ ++Y ++N
Sbjct: 1089 DYYNERLYWADAKLSVIGSVRLDGSDPVIAVSGIKNNLLHPFSIDIFEDYIYGVTYINNI 1148
Query: 8050 VFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLC 8229
VFR++K +EN+ + SD+ ++ + C D C+ LC
Sbjct: 1149 VFRVNKFGKGTMENLTTG---------INHASDIVLHHRYKQPEMTNPC--DRKKCEWLC 1197
Query: 8230 TVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVLRGSNSE-PAKECLPPYNFQCGD 8406
L+ S C+C + Y V + G CV R ++ P P + QC +
Sbjct: 1198 L-------LSPSGPVCTCPNKY--VADNG-----TCVERPKPTQSPFSPPSEPCDIQCLN 1243
Query: 8407 GSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHIDDCGDG 8586
G L A +K C P+Y R C +C D K G
Sbjct: 1244 GGSCFLNARQVAKCRC------QPSYIGDR--------CDINQCRDYCKNGGTCTASHAG 1289
Query: 8587 SDELDCPSAVACAEGTFPCSNGHCIN--QTKVCDGHN---DCHDEQVSDE-SLATCPGLP 8748
CP + +C+N + V G+ C E D+ TC G
Sbjct: 1290 VPTCRCPKGFTGPTCSRQTCQDYCLNGGRCSVNTGNQPTCSCPSEYQGDQCQYTTCEGF- 1348
Query: 8749 IDCRGVKVRCPNTNICIQPAD-----LCDG-YDDCGDKADENQLFCMNQQCA-----QHY 8895
C N+ C+Q ++ LC Y + D+ Q FC +C+ +
Sbjct: 1349 ---------CHNSGTCLQTSNGTKLCLCSSKYIGHQCELDKCQ-FCGTGKCSTSPTNEVT 1398
Query: 8896 VRCPSGRCIPETWQCDGDNDCSDG 8967
CP+G+ P + C N CS G
Sbjct: 1399 CSCPNGQIQPSCYTC--LNYCSRG 1420
Score = 104 bits (259), Expect = 7e-20
Identities = 65/240 (27%), Positives = 112/240 (46%), Gaps = 5/240 (2%)
Frame = +1
Query: 6616 KSLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWA 6795
+ +A+DW+ N+Y+ D+ R IEV+++ G + K L++ + P +I VDP +YWA
Sbjct: 997 RGIAVDWVAGNLYWT--DSGRDVIEVAQMSGQHCKTLISGMIDEPYAIVVDPQRGTMYWA 1054
Query: 6796 DQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGT 6975
D G P I+ + +DG+ R+ +V I PT L VD ++ +YW+DAK+ I VR G
Sbjct: 1055 DWGNHPKIETAAMDGTLRQTLVHENIQWPTGLAVDYYNERLYWADAKLSVIGSVRLDGSD 1114
Query: 6976 PEL----VRSDIASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKD 7143
P + +++++ + + +Y +FR T + +
Sbjct: 1115 PVIAVSGIKNNLLHPFSIDIFEDYIYGVTYINNIVFRVNKFGKGTM-----ENLTTGINH 1169
Query: 7144 IGDVAVFSSNNQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCA-RGVLKGRTCEE 7320
D+ + QP ++PC + C LC +P P C+C + V TC E
Sbjct: 1170 ASDIVLHHRYKQPEMTNPCD------RKKCEWLCLLSP--SGPVCTCPNKYVADNGTCVE 1221
Score = 87.4 bits (215), Expect = 9e-15
Identities = 84/373 (22%), Positives = 152/373 (40%), Gaps = 5/373 (1%)
Frame = +1
Query: 5254 STNPCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNVFGIEMNSASE 5433
+T PCS C+ N +F C C G +L + I + +L+ + + + ++ ++
Sbjct: 24 TTYPCSQRCI-NTHGSFHCLCVDGFELSPNDPT-ICKRRTYLIFANRYYLRKLNLDGSNY 81
Query: 5434 KETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNGGN 5613
+ GL NA + + ++ + T T S I R +NG +
Sbjct: 82 T--------LIKQGLNNAVALDFHYAEQMIYWTDVT---------TQGSMIRRMRMNGSS 124
Query: 5614 KTKMFSSAV--PDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVILSNDQSXXX 5787
+ +++ PD L DW G NL +K TIE+ + G YR+V++++
Sbjct: 125 MEVLHRTSLSNPDG---LAVDWVGGNLYWCDKGRDTIEVSKLNGA-YRTVLVNSGLREPR 180
Query: 5788 XXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAIDTTN 5967
GY++W D G + R G+DG+N VI + + + +D N
Sbjct: 181 ALAVDVRY-----GYLYWSDWGDSP---HIGRIGMDGTNRSVIVEEKITWPNGLTLDFIN 232
Query: 5968 TRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAFDSIEVATIN 6147
R+Y+++A+ I + DG +RH VL+ + + + +++ D SI A
Sbjct: 233 DRIYWADAREDYIEFASLDGTNRHTVLNHDIPHIFAMTLFEEYIYWTDWETKSINRA--- 289
Query: 6148 GDSQPPQWTHFKKDVENLANIKALQP--RASSSGHPCHINNGNCDHICIPLMFAQRTCTC 6321
+Q T + ++ P + HPC NNG C ++C+ C C
Sbjct: 290 HKTQGTNKTTLISTLHRPMDVHIYHPYRQPEVLNHPCQTNNGGCSNLCLLSPGGGYKCAC 349
Query: 6322 -ANGYVKDGQTSC 6357
N Y+ +C
Sbjct: 350 PTNFYLASDHRTC 362
Score = 71.6 bits (174), Expect = 5e-10
Identities = 74/309 (23%), Positives = 129/309 (40%), Gaps = 9/309 (2%)
Frame = +1
Query: 2404 MSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPWKGLL 2583
++ DW++ LY+ D+ R+ +EV ++ H L+ + +P ++VV P +G +
Sbjct: 999 IAVDWVAGNLYWTDSGRDVIEVAQMSGQ---HCKTLISGMI----DEPYAIVVDPQRGTM 1051
Query: 2584 FYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFD 2763
++A+ I +DG Q + + + P+ +A+D+ RL W D L I + D
Sbjct: 1052 YWADWGNHPKIETAAMDGTLRQTLVHENIQWPTGLAVDYYNERLYWADAKLSVIGSVRLD 1111
Query: 2764 GKN--VVKLDIDNPI--PVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADER 2931
G + + I N + P +I I +YIY V + RV+ K G G+ G +
Sbjct: 1112 GSDPVIAVSGIKNNLLHPFSIDIFEDYIYGVTYINNIVFRVN-KFGKGTMENLTTGINHA 1170
Query: 2932 SIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINKE 3111
S L H P+ +PC +C LC +PS C C ++
Sbjct: 1171 SDIVL----HHRYKQPE--MTNPCDRKKCEWLCLLSPS-------GPVCTCPNKYV---A 1214
Query: 3112 NNHSCQKDPAEKIEQLC-SSNSTQFQCKN-GRCI---PKEWKCDGENDCLDESDEIDEKG 3276
+N +C + P S QC N G C + KC + + + +I++
Sbjct: 1215 DNGTCVERPKPTQSPFSPPSEPCDIQCLNGGSCFLNARQVAKCRCQPSYIGDRCDINQCR 1274
Query: 3277 DKCFHETEC 3303
D C + C
Sbjct: 1275 DYCKNGGTC 1283
Score = 47.4 bits (111), Expect = 0.010
Identities = 53/237 (22%), Positives = 96/237 (40%), Gaps = 6/237 (2%)
Frame = +1
Query: 5659 LGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVILSNDQSXXXXXXXXXXXXXXXKGYVF 5838
+ DW NL + IE+ + G+ +++I +G ++
Sbjct: 999 IAVDWVAGNLYWTDSGRDVIEVAQMSGQHCKTLI------SGMIDEPYAIVVDPQRGTMY 1052
Query: 5839 WLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAIDTTNTRVYFSEAKAGRISSVT 6018
W D G K+ A +DG+ + ++ +A+D N R+Y+++AK I SV
Sbjct: 1053 WADWGN---HPKIETAAMDGTLRQTLVHENIQWPTGLAVDYYNERLYWADAKLSVIGSVR 1109
Query: 6019 YDGQDRHYVLSDGGRQPNGLAFYGDRLF----YADSAFDSI--EVATINGDSQPPQWTHF 6180
DG D V++ G + N L + +F Y + ++I V + T
Sbjct: 1110 LDGSDP--VIAVSGIKNNLLHPFSIDIFEDYIYGVTYINNIVFRVNKFGKGTMENLTTGI 1167
Query: 6181 KKDVENLANIKALQPRASSSGHPCHINNGNCDHICIPLMFAQRTCTCANGYVKDGQT 6351
+ + + + QP + +PC + C+ +C+ L + CTC N YV D T
Sbjct: 1168 NHASDIVLHHRYKQPEMT---NPC--DRKKCEWLCL-LSPSGPVCTCPNKYVADNGT 1218
Score = 37.7 bits (86), Expect = 8.3
Identities = 40/150 (26%), Positives = 51/150 (33%), Gaps = 11/150 (7%)
Frame = +1
Query: 667 CTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLC 846
C N Q RCQP GD D ++C +Y C G C
Sbjct: 1247 CFLNARQVAKCRCQPSYI--------GDRCDINQCRDY--------CKNGGTCTASHAGV 1290
Query: 847 DGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGE---CTCPSGYKLDDRFHRTCSDI 1017
+ C G CS+ C C G S + G C+CPS Y+ D + TC
Sbjct: 1291 PTCR-CPKGFTGPTCSRQTCQDY-CLNGGRCSVNTGNQPTCSCPSEYQGDQCQYTTCEGF 1348
Query: 1018 NECAEFGYCDQ--------LCANHRPGFTC 1083
C G C Q LC++ G C
Sbjct: 1349 --CHNSGTCLQTSNGTKLCLCSSKYIGHQC 1376
>gi|17298316|gb|AAL38108.1| candidate tumor suppressor protein [Homo
sapiens]
Length = 1731
Score = 731 bits (1888), Expect = 0.0
Identities = 549/1841 (29%), Positives = 850/1841 (45%), Gaps = 93/1841 (5%)
Frame = +1
Query: 3556 TCAANQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSAL-QFRCANGRQCVPL 3732
TC +QFSC NGRCIP WLCD ++DC D TDE C C L QF C +GR C+
Sbjct: 2 TCQVDQFSCGNGRCIPRAWLCDREDDCGDQTDE-MASCEFPTCEPLTQFVCKSGR-CISS 59
Query: 3733 RNHXXXXXXXXXXXXXXXXAVTAESCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPK 3912
+ H SC +QF+C SSG CIP W SDE +
Sbjct: 60 KWHCDSDDDCGDGSDEVG---CVHSCFDNQFRC-SSGRCIPGHWACDGDNDCGDFSDEAQ 115
Query: 3913 FGCT-----SGRQCSSDQFKCG-NGRCILNNWLCDGENDCGDGSDESSERG--------- 4047
CT S C+ ++F+C +G C+ + W CDGE DC DGSDE G
Sbjct: 116 INCTKEEIHSPAGCNGNEFQCHPDGNCVPDLWRCDGEKDCEDGSDEKGCNGTIRLCDHKT 175
Query: 4048 ----------------------CKTSMNARKC------PFEHVACENDQETCIPLHQLCD 4143
C+ + C P +H C ND C+ +LC+
Sbjct: 176 KFSCWSTGRCINKAWVCDGDIDCEDQSDEDDCDSFLCGPPKH-PCANDTSVCLQPEKLCN 234
Query: 4144 GKTHCPGGTDEGGRCARDLCSADRAGCSFKCHNSPN-GPICSCPFGEQLVNKTK-CEPEN 4317
GK CP G+DEG C D CS + GCS C P G +CSCP G QL K CE +
Sbjct: 235 GKKDCPDGSDEGYLC--DECSLNNGGCSNHCSVVPGRGIVCSCPEGLQLNKDNKTCEIVD 292
Query: 4318 ECLDSSSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDH 4497
C + CSQ C+ KH CSC EG++LDVD +C D+ + I+ S R+ I D
Sbjct: 293 YCSNHLKCSQVCEQHKHTVKCSCYEGWKLDVDGESCTSVDSFEAFIIF-SIRHEIRRIDL 351
Query: 4498 KLDNWHTFGAIVENAIALAWDSLTDRIYWSDIREKKI----LSANRNGTNATVFIADGLD 4665
++ + N IAL + +YW+D+ E +I LS + + V + GL
Sbjct: 352 HKRDYSLLVPGLRNTIALDFHFNQSLLYWTDVVEDRIYRGKLSESGGVSAIEVVVEHGLA 411
Query: 4666 ITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFW 4845
EG+ +DW+ N+YW+DS+L+ IEVA L D RT L+ + PR IA+DPR G++FW
Sbjct: 412 TPEGLTVDWIAGNIYWIDSNLDQIEVAKL-DGSLRTTLIAGAMEHPRAIALDPRYGILFW 470
Query: 4846 TDWGQN-PCIERASMDGTDRQIIVKTKIY--WPNTIALDYTTDRVYFADSKLDFIDFVNY 5016
TDW N P IE ASM G R+ I K WPN + +D+ R+ + D++ D I Y
Sbjct: 471 TDWDANFPRIESASMSGAGRKTIYKDMKTGAWPNGLTVDHFEKRIVWTDARSDAIYSALY 530
Query: 5017 DGSGRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKA 5196
DG+ +++ +++ HP A++++ +Y++D R L K+ G T ++
Sbjct: 531 DGTNMIEIIRGHEYLSHPFAVSLYGSEVYWTDWRTNTLSKANKW-TGQNVSVIQKTSAQP 589
Query: 5197 LGVVAVHPVLQPVIKNNPCSTN----PCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDD 5364
+ HP QP N PC+ N PCSH+CL+N+ + C CP KL + K C
Sbjct: 590 FDLQIYHPSRQPQAPN-PCAANDGKGPCSHMCLINHNRSAACACPHLMKLSSDKKTCYG- 647
Query: 5365 AKPFLVIIQKTNVFGIEMNSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTN 5544
K FL+ +++ + G+++++ + A VP + + +DA E ++ +
Sbjct: 648 MKKFLLYARRSEIRGVDIDNPYFNF--ITAFTVP--DIDDVTVIDFDASEERLYWTD--- 700
Query: 5545 HAKTLAQITTDSAIYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLV-VGNKITQT-I 5718
I T + I R+ +NG + S + L DW RNL + ++ +T I
Sbjct: 701 -------IKTQT-IKRAFINGTGLETVISRDI-QSIRGLAVDWVSRNLYWISSEFDETQI 751
Query: 5719 EIIRTQGKQYRSVILSNDQSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDG 5898
+ R G S+I D+ +G ++W D + A +DG
Sbjct: 752 NVARLDGSLKTSIIHGIDKPQCLAAHPV-------RGKLYWTDGN------TINMANMDG 798
Query: 5899 SNPLVIASNDLAELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYV--LSDGGRQPN 6072
SN ++ N + ++ID ++Y+ + G I+ DG + + + + +
Sbjct: 799 SNSKILFQNQKEPVG-LSIDYVENKLYWISSGNGTINRCNLDGGNLEVIESMKEELTKAT 857
Query: 6073 GLAFYGDRLFYADSAFDSIEVATINGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPC 6252
L +L++AD + + P T + + ++K A + C
Sbjct: 858 ALTIMDKKLWWADQNLAQLGTCSKRDGRNP---TILRNKTSGVVHMKVYDKEAQQGSNSC 914
Query: 6253 HINNGNCDHICIPLMFAQRTCTCANGY-VKDGQTSCKLFDESFVIVATKTKVIGYPIDET 6429
+NNG C +C+P RTC C GY ++ + SC+ ESF++ + + G P+ E
Sbjct: 915 QLNNGGCSQLCLPTSETTRTCMCTVGYYLQKNRMSCQGI-ESFLMYSVHEGIRGIPL-EP 972
Query: 6430 QSKGVAMEPIGGLSIT-GVDYDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGS 6606
K A+ PI G S G+D+ E+ TIY + G NK I+ ++ +I + +G
Sbjct: 973 SDKMDALMPISGTSFAVGIDFHAENDTIYWTDM-GFNK-ISRAKRDQTWKEDIITNGLGR 1030
Query: 6607 LTIKSLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYL 6786
++ +A+DWI N+Y+ +H IEV++L+G++R ++++ + P SIAV P L
Sbjct: 1031 --VEGIAVDWIAGNIYWTDHGFNL--IEVARLNGSFRYVIISQGLDQPRSIAVHPEKGLL 1086
Query: 6787 YWADQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVR-S 6963
+W + GQ P I ++ LDGS + V+VS GIA P + +D +YW DA+ D I R+
Sbjct: 1087 FWTEWGQMPCIGKARLDGSEKVVLVSMGIAWPNGISIDYEENKLYWCDARTDKIERIDLE 1146
Query: 6964 TGGTPELVRSDI-ASAAGVALHGQNMYWTDN-RLEKLFRATSKPNQTSLLLSPTTVAASL 7137
TGG E+V S VA G +YW+D R K + T + T + +L
Sbjct: 1147 TGGNREMVLSGSNVDMFSVAXFGAYIYWSDRAHANGSVRRGHKNDATETITMRTGLGVNL 1206
Query: 7138 KDIGDVAVFSSNNQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCARGVLK--GRT 7311
K+ V +F+ + + ++ C DN C QLC G TC+CA G L G T
Sbjct: 1207 KE---VKIFNRVRE-KGTNVCA-RDN---GGCKQLCLYR-GNSRRTCACAHGYLAEDGVT 1257
Query: 7312 CEEPDTYIMFSDGDKIIDVAIEPDVKASRPLKDPFPE---ISNLQTFDVDVNLRRVYFVV 7482
C + Y+++S + + + + + P++ P+ N+ D N RR
Sbjct: 1258 CLRHEGYLLYSGRTILKSIHLSDETNLNSPIR-PYENPRYFKNVIALAFDYNQRRK---- 1312
Query: 7483 ESPVGVNISWFSMNNAENPRLVFG--ASKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGK 7656
G N ++S + N +L+ +Q + + + + +Y+T+
Sbjct: 1313 ----GTNRIFYSDAHFGNIQLIKDNWEDRQVIVENVGSVEGLAYHRAWDTLYWTSSTTSS 1368
Query: 7657 VM--AIDTAG------EHLSTIASGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIER 7812
+ +D E + T++ D + LA+D C L+FW T+ P I R
Sbjct: 1369 ITRHTVDQTRPGAFDREAVITMSEDDHPHVLALDECQNLMFW------TNWNEQHPSIMR 1422
Query: 7813 SNLAGGSRKVIVSESISLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGYRA 7992
S L G + +V+VS I P + +D+R +K+Y++D + IE +YDG R VI
Sbjct: 1423 STLTGKNAQVVVSTDILTPNGLTIDYRAEKLYFSDGSLGKIERCEYDGSQRHVIVKSGPG 1482
Query: 7993 K--SLDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVSDRRIPGA-LRVFASESDVRTRN 8163
SL ++D +++ SD + R +K +G + + SD IP + + A +D
Sbjct: 1483 TFLSLAVYDNYIFWSDWGRRAILRSNKYTGGDTKILRSD--IPHQPMGIIAVANDT---- 1536
Query: 8164 QVCNALTSQLCKTDNGGCDQLCTVVADDIGLAASKVQCSCNDTYELVQEPGKDYPTQCVL 8343
N+ C NGGC LC + + +V CSC L+++ +CV
Sbjct: 1537 ---NSCELSPCALLNGGCHDLCLLTPN------GRVNCSCRGDRILLED------NRCVT 1581
Query: 8344 RGSNSEPAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLC 8523
+ S+ E F+CG+G CI TCD P C D SDE YC RSC + C
Sbjct: 1582 KNSSCNAYSE------FECGNGECIDYQLTCDGIPHCKDKSDEKLLYCENRSCRRGFKPC 1635
Query: 8524 TNRRCIDSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHD 8703
NRRCI K C+ +DCGD SDELDC CA F C++G CI ++ C+ + DC D
Sbjct: 1636 YNRRCIPHGKLCDGENDCGDNSDELDC-KVSTCATVEFRCADGTCIPRSARCNQNIDCAD 1694
Query: 8704 EQVSDESLATCPGLPIDCR-----GVK----VRCPNTNICI 8799
SDE C DC GVK +RC +T++C+
Sbjct: 1695 --ASDEK--NCNN--TDCTHFYKLGVKTTGFIRCNSTSLCV 1729
Score = 375 bits (962), Expect = e-101
Identities = 240/721 (33%), Positives = 335/721 (46%), Gaps = 16/721 (2%)
Frame = +1
Query: 8755 CRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQ--HYVRCPSGRCIPE 8928
C+ + C N CI A LCD DDCGD+ DE C C +V C SGRCI
Sbjct: 3 CQVDQFSCGNGR-CIPRAWLCDREDDCGDQTDE-MASCEFPTCEPLTQFV-CKSGRCISS 59
Query: 8929 TWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXXXX 9108
W CD D+DC DG DE
Sbjct: 60 KWHCDSDDDCGDGSDEV------------------------------------------- 76
Query: 9109 XXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTE 9288
GC + +C D +F C+S CIP W CDGD C DE+ C E
Sbjct: 77 ------GCVH-SCFDNQFRCSSG--------RCIPGHWACDGDNDCGDFSDEAQINCTKE 121
Query: 9289 KKE----CNKGEFRCS-NQHCIHSTWECDGDNDCLDGSDEHA-NCTYSSCQPDF-FQC-A 9444
+ CN EF+C + +C+ W CDG+ DC DGSDE N T C F C +
Sbjct: 122 EIHSPAGCNGNEFQCHPDGNCVPDLWRCDGEKDCEDGSDEKGCNGTIRLCDHKTKFSCWS 181
Query: 9445 NHKCVPNSWKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDR 9624
+C+ +W CDG+ DCED SDE DC K C+N + C+ K+C+
Sbjct: 182 TGRCINKAWVCDGDIDCEDQSDEDDCDSFLCGPPK-HPCAND-----TSVCLQPEKLCNG 235
Query: 9625 NFDCTDRSDESSLCFIDECSLAEKPLCEQKCMDMK-IGYKCDCFEGFAIDISDQKSCHNV 9801
DC D SDE LC DECSL C C + G C C EG ++ D K+C V
Sbjct: 236 KKDCPDGSDEGYLC--DECSLNNGG-CSNHCSVVPGRGIVCSCPEGLQLN-KDNKTCEIV 291
Query: 9802 NECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKI 9981
+ C + CSQ C+ + KC C +G++L D SC + E F + + +H IR+I
Sbjct: 292 DYCSNHLK-CSQVCEQHKHTVKCSCYEGWKLDVDGESCTSVDSF-EAFIIFSIRHEIRRI 349
Query: 9982 SIDGNKYELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRH 10161
+ Y L G N ++LD + Y D + R+ R L E +S+ E V+ H
Sbjct: 350 DLHKRDYSLLVPGLRNTIALDFHFNQSLLYWTDVVEDRIYRGKLSESGG-VSAIEVVVEH 408
Query: 10162 NVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYL 10341
+ EG+ VDW+ +Y ++ I V +LDG TLI ++ P+AI + P G L
Sbjct: 409 GLATPEGLTVDWIAGNIYWIDSNLDQIEVAKLDGSLRTTLIAGAMEHPRAIALDPRYGIL 468
Query: 10342 FFTEWSLQ-PYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEI 10518
F+T+W P I ++ G+ + I+K + WPN + +D+F R+ W DA + I
Sbjct: 469 FWTDWDANFPRIESASMSGAG--RKTIYKDMKTG-AWPNGLTVDHFEKRIVWTDARSDAI 525
Query: 10519 GFMDFDGNGRRHIPA--QRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKT 10692
+DG I + SH ++ ++ +YW DW + + +KWTG+N ++++KT
Sbjct: 526 YSALYDGTNMIEIIRGHEYLSHPFAVSLYGSEVYWTDWRTNTLSKANKWTGQNVSVIQKT 585
Query: 10693 VQLPNDLRIVHPMRQPAYPNPC--GDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKT 10866
P DL+I HP RQP PNPC D G CSH+CLI + C+CP L SD+KT
Sbjct: 586 SAQPFDLQIYHPSRQPQAPNPCAANDGKGPCSHMCLINHNRSA-ACACPHLMKLSSDKKT 644
Query: 10867 C 10869
C
Sbjct: 645 C 645
Score = 367 bits (941), Expect = 6e-99
Identities = 279/1029 (27%), Positives = 450/1029 (43%), Gaps = 38/1029 (3%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXX-PHPGCKS-DQWQCDTYTWHSVSCI 330
C + F C +G+CI W P C+ Q+ C S CI
Sbjct: 3 CQVDQFSCGNGRCIPRAWLCDREDDCGDQTDEMASCEFPTCEPLTQFVCK-----SGRCI 57
Query: 331 AEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSD 510
+ CD+ DC DGSDE C S D N F C+ GR C CDG DC D SD
Sbjct: 58 SSKWHCDSDDDCGDGSDEVGCVHSCFD----NQFRCSSGR-CIPGHWACDGDNDCGDFSD 112
Query: 511 EKD-SCSRNH----TACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDT------CE 657
E +C++ C +F+C C+ W CDG KDC DGSDE C+
Sbjct: 113 EAQINCTKEEIHSPAGCNGNEFQCHPDGNCVPDLWRCDGEKDCEDGSDEKGCNGTIRLCD 172
Query: 658 FKKCTANEFQC-KNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPG-TGHCID 831
K +F C RC + + CD DC D SDED+C + C P K C T C+
Sbjct: 173 HK----TKFSCWSTGRCINKAWVCDGDIDCEDQSDEDDCDSFLCGPPKHPCANDTSVCLQ 228
Query: 832 QLKLCDGSKDCADGADE----QQCSQNLCPSLGCQAGCHPSPHGG-ECTCPSGYKLDDRF 996
KLC+G KDC DG+DE +CS N + GC C P G C+CP G +L+ +
Sbjct: 229 PEKLCNGKKDCPDGSDEGYLCDECSLN---NGGCSNHCSVVPGRGIVCSCPEGLQLN-KD 284
Query: 997 HRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNA 1176
++TC ++ C+ C Q+C H+ CSC + + L ++ G+ C S ++
Sbjct: 285 NKTCEIVDYCSNHLKCSQVCEQHKHTVKCSCY-EGWKLDVD---GES-------CTSVDS 333
Query: 1177 DKMKLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSAD 1356
+ + + R + R++ D + I +DF + ++WTD + +
Sbjct: 334 FEAFIIFSIRHEIRRIDLHKRDYSLLVPGLRNTI-ALDFHFNQSLLYWTDVVEDRIYRGK 392
Query: 1357 VDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADG 1536
+ + G +S I+ + L P L VDWI +Y I+S +I+V+ DG RT L+A
Sbjct: 393 LSESGGVSAIEVVVEHGLATPEGLTVDWIAGNIYWIDSNLDQIEVAKLDGSLRTTLIAGA 452
Query: 1537 LTLPLDIALDPLRGEMFFT----NQLKLEAAAMDGTNRRTLVNTHTHQV--SGIVVDITA 1698
+ P IALDP G +F+T N ++E+A+M G R+T+ +G+ VD
Sbjct: 453 MEHPRAIALDPRYGILFWTDWDANFPRIESASMSGAGRKTIYKDMKTGAWPNGLTVDHFE 512
Query: 1699 KRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVE 1878
KR+ W D + D + S Y G + + +G + HPF ++L+ +YWTDW + +
Sbjct: 513 KRIVWTDARSDAIYSALYDGTNMIEIIRGHEYLSHPFAVSLYGSEVYWTDWRTNTLSKAN 572
Query: 1879 KF-GSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNAD----CEGM 2043
K+ G + ++ + + P + YHP QP + NPC D C M
Sbjct: 573 KWTGQNVSVI---QKTSAQPFDLQIYHPSRQP----------QAPNPCAANDGKGPCSHM 619
Query: 2044 CILSKDNGGFGVGYKCACPIGQKLVNGKR-CIDSIDYLLFSSNKIVRGI---FPEINEKA 2211
C+++ + CACP KL + K+ C +LL++ +RG+ P N
Sbjct: 620 CLINHNRSA-----ACACPHLMKLSSDKKTCYGMKKFLLYARRSEIRGVDIDNPYFNF-- 672
Query: 2212 LAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHND 2391
I+ + I ++ D ++ DI TI R +G G V+
Sbjct: 673 -------ITAFTVPDIDDVTVIDFDASEERLYWTDIKTQTIKRAFINGTGLETVISRDIQ 725
Query: 2392 GLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRDPVSVVVHPW 2571
+ ++ DW+S+ LY++ + + ++ + D ++ +I + P + HP
Sbjct: 726 SIRGLAVDWVSRNLYWISSEFDETQI------NVARLDGSLKTSIIHGIDKPQCLAAHPV 779
Query: 2572 KGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISC 2751
+G L++ + I ++DG N +++ P ++ID+ EN+L W + TI+
Sbjct: 780 RGKLYWTDG---NTINMANMDGSNSKILFQNQ-KEPVGLSIDYVENKLYWISSGNGTINR 835
Query: 2752 MDFDGKN---VVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGA 2922
+ DG N + + + A+TIM++ +++ Q + K++G I+R
Sbjct: 836 CNLDGGNLEVIESMKEELTKATALTIMDKKLWWADQNLAQLGTCSKRDGRNPTILRN--- 892
Query: 2923 DERSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMI 3102
+ +K + Q S C+QLC T +E C C G+ +
Sbjct: 893 KTSGVVHMKVYDKEAQ---QGSNSCQLNNGGCSQLCLPT------SETTRTCMCTVGYYL 943
Query: 3103 NKENNHSCQ 3129
K N SCQ
Sbjct: 944 QK-NRMSCQ 951
Score = 233 bits (593), Expect = 1e-58
Identities = 193/694 (27%), Positives = 294/694 (41%), Gaps = 22/694 (3%)
Frame = +1
Query: 11494 TCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSE-SEFRCNDGKC 11670
TC V +F C +G+CIPR W+CD E+DCGD +DE+ ASC T C ++F C G+C
Sbjct: 2 TCQ-VDQFSCG-NGRCIPRAWLCDREDDCGDQTDEM-ASCEFPT--CEPLTQFVCKSGRC 56
Query: 11671 IPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADE-- 11844
I CD C DG DE C + C +C G CI H CD DC + +DE
Sbjct: 57 ISSKWHCDSDDDCGDGSDEVGC-VHSCFDNQFRCSSGRCIPGHWACDGDNDCGDFSDEAQ 115
Query: 11845 LHC---EDVSRRTCSPFEFEC-ANSVCIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPL 12012
++C E S C+ EF+C + C+P + SDE CD
Sbjct: 116 INCTKEEIHSPAGCNGNEFQCHPDGNCVPDLWRCDGEKDCEDGSDEKGCNGTIRLCDHKT 175
Query: 12013 RFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSFSEYGDCSSDQFKCANGK--CV 12186
+F C + C+N +C+G DC D SDE C SF C + CAN C+
Sbjct: 176 KFSCWSTGRCINKAWVCDGDIDC--EDQSDE--DDCDSFL----CGPPKHPCANDTSVCL 227
Query: 12187 NGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKHICTDVRD-GFYCHCRDGFR 12363
C+ K DC D SDE G E NNGGC + C+ V G C C +G +
Sbjct: 228 QPEKLCNGKKDCPDGSDE-------GYLCDECSLNNGGCSNHCSVVPGRGIVCSCPEGLQ 280
Query: 12364 PDPQSPKECIDIDECAGNNTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDA 12543
+ + K C +D C+ + C+Q+C K + C C+E ++ +V S T D
Sbjct: 281 LNKDN-KTCEIVDYCSNHLKCSQVCEQHKHTVKCSCYEGWKLDVDGESCTSVD----SFE 335
Query: 12544 ANVMIGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERTIYR 12723
A ++ + ++ LH + + L+YW D E IYR
Sbjct: 336 AFIIFSIRHEIRRIDLH-----KRDYSLLVPGLRNTIALDFHFNQSLLYWTDVVEDRIYR 390
Query: 12724 SAIANGNQSHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMS 12903
+ ++S ++V P + VD+ GN++ + N++
Sbjct: 391 GKL---SESGGVSAIEVVVEHGLATPEGLTVDWIAGNIY--WIDSNLDQ----------- 434
Query: 12904 EPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLH-AKIECAD 13080
I V DG ++AG ++ P A+ P G + ++D + +IE A
Sbjct: 435 ----------IEVAKLDGSLRTTLIAGAMEHPRAIALDPRYGILFWTDWDANFPRIESAS 484
Query: 13081 MDGTHRQIIVKDLVFS--PTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRH 13254
M G R+ I KD+ P + +D + RI W D + + + DG+ ++
Sbjct: 485 MSGAGRKTIYKDMKTGAWPNGLTVDHFE-KRIVWTDARSDAIYSALYDGTNMIEIIRGHE 543
Query: 13255 I---PYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLAS------DLEDGHTVRVSQK 13407
P+AV ++ + +YW + TL +K+ VSV+ DL+ H R Q
Sbjct: 544 YLSHPFAVSLYGSEVYWTDWRTNTLSKANKWTGQNVSVIQKTSAQPFDLQIYHPSR--QP 601
Query: 13408 YAKDTQRTVSGCERAQCSHLCVSLPSTGFACLCP 13509
A + G + CSH+C+ + AC CP
Sbjct: 602 QAPNPCAANDG--KGPCSHMCLINHNRSAACACP 633
Score = 186 bits (471), Expect = 2e-44
Identities = 193/799 (24%), Positives = 333/799 (41%), Gaps = 19/799 (2%)
Frame = +1
Query: 1222 LNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSL 1401
L P + + + ++ F GIDF + I+WTD + A D + + +
Sbjct: 970 LEPSDKMDALMPISGTSFAVGIDFHAENDTIYWTDMGFNKISRAKRDQTWK----EDIIT 1025
Query: 1402 KSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGE 1581
L +AVDWI +Y + G I+V+ +G R V+++ GL P IA+ P +G
Sbjct: 1026 NGLGRVEGIAVDWIAGNIYWTDHGFNLIEVARLNGSFRYVIISQGLDQPRSIAVHPEKGL 1085
Query: 1582 MFFTNQLKLEA---AAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDY 1752
+F+T ++ A +DG+ + LV+ +GI +D ++YW D + D++E ID
Sbjct: 1086 LFWTEWGQMPCIGKARLDGSEKVVLVSMGIAWPNGISIDYEENKLYWCDARTDKIERIDL 1145
Query: 1753 Q-GNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRL-GVIQVEKFGSDTKLLWSNTENN 1926
+ G +R +V G NV F +A F Y+YW+D G ++ T+ + T
Sbjct: 1146 ETGGNREMVLSGSNV--DMFSVAXFGAYIYWSDRAHANGSVRRGHKNDATETITMRTGLG 1203
Query: 1927 VFPMGISAYHPMAQPGPGQSECLAMKIENPCT--NADCEGMCILSKDNGGFGVGYKCACP 2100
V + ++ + + G N C N C+ +C+ ++ CAC
Sbjct: 1204 VNLKEVKIFNRVREKGT-----------NVCARDNGGCKQLCLYRGNSRR-----TCACA 1247
Query: 2101 IGQKLVNGKRCIDSIDYLLFSSNKIVRGIFPEINEKALAEAVLPISPISQRR-----IGM 2265
G +G C+ YLL+S I++ I ++++ + PI P R I +
Sbjct: 1248 HGYLAEDGVTCLRHEGYLLYSGRTILKSI--HLSDETNLNS--PIRPYENPRYFKNVIAL 1303
Query: 2266 YFEVECDVHG-NSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWISKQLYYV 2442
F+ G N FY+D I I+ + E V+V + + +++ LY+
Sbjct: 1304 AFDYNQRRKGTNRIFYSDAHFGNIQLIKDNWEDRQ-VIVENVGSVEGLAYHRAWDTLYWT 1362
Query: 2443 DNIRNSLEVVKIGETGLVHPDELVRRQLITELRD--PVSVVVHPWKGLLFYAE-AMRPAA 2613
+ +S+ + +T P R +IT D P + + + L+F+ + +
Sbjct: 1363 SSTTSSITRHTVDQT---RPGAFDREAVITMSEDDHPHVLALDECQNLMFWTNWNEQHPS 1419
Query: 2614 IYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVKLDID 2793
I R + G+N QV+ +T + P+ + ID+ +L + D L I ++DG +
Sbjct: 1420 IMRSTLTGKNAQVVVSTDILTPNGLTIDYRAEKLYFSDGSLGKIERCEYDGSQRHVIVKS 1479
Query: 2794 NPIP-VAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQ 2970
P +++ + + YI++ +I R +K GG +KI+R + + + + N
Sbjct: 1480 GPGTFLSLAVYDNYIFWSDWGRRAILRSNKYTGGDTKILRS-DIPHQPMGIIAVANDTNS 1538
Query: 2971 PIPDDSREHPCRASQ--CTQLCFATPSESHPNELEAKCACRQGFMINKENNHSCQKDPAE 3144
PC C LC TP+ C+CR G I E+N K+ +
Sbjct: 1539 -----CELSPCALLNGGCHDLCLLTPNG------RVNCSCR-GDRILLEDNRCVTKNSS- 1585
Query: 3145 KIEQLCSSNSTQFQCKNGRCIPKEWKCDGENDCLDESDEIDEKGDKCFHETECAENTIKC 3324
C++ S +F+C NG CI + CDG C D+SDE K C + + C C
Sbjct: 1586 -----CNAYS-EFECGNGECIDYQLTCDGIPHCKDKSDE---KLLYCENRS-CRRGFKPC 1635
Query: 3325 RNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNHRCIPEQWKXXXX 3504
N ++CIP D + CA +F+C + CIP +
Sbjct: 1636 YN-RRCIPHGKLCDGENDCGDNSDEL-----DCKVSTCATVEFRCADGTCIPRSARCNQN 1689
Query: 3505 XXXXXXXXEKLEMCGNATC 3561
EK C N C
Sbjct: 1690 IDCADASDEK--NCNNTDC 1706
Score = 165 bits (418), Expect = 3e-38
Identities = 148/618 (23%), Positives = 267/618 (42%), Gaps = 13/618 (2%)
Frame = +1
Query: 1285 IDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYII 1464
IDFD + +++WTD + A ++ G + I + ++S+ R LAVDW++ LY I
Sbjct: 687 IDFDASEERLYWTDIKTQTIKRAFINGTGLETVISR-DIQSI---RGLAVDWVSRNLYWI 742
Query: 1465 ES--GSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTNQLKLEAAAMDGTNR 1638
S +I+V+ DG +T ++ G+ P +A P+RG++++T+ + A MDG+N
Sbjct: 743 SSEFDETQINVARLDGSLKTSII-HGIDKPQCLAAHPVRGKLYWTDGNTINMANMDGSNS 801
Query: 1639 RTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLA 1818
+ L V G+ +D ++YW+ + + G + ++ + L
Sbjct: 802 KILFQNQKEPV-GLSIDYVENKLYWISSGNGTINRCNLDGGNLEVIESMKEELTKATALT 860
Query: 1819 LFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLA 1998
+ D+ L+W D + K + N + V M + Y AQ G +
Sbjct: 861 IMDKKLWWADQNLAQLGTCSKRDGRNPTILRNKTSGVVHMKV--YDKEAQQGSNSCQL-- 916
Query: 1999 MKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGKRCIDSID-YLLFSSNKI 2175
N C +C+ + + C C +G L + I+ +L++S ++
Sbjct: 917 -------NNGGCSQLCLPTSETTR-----TCMCTVGYYLQKNRMSCQGIESFLMYSVHEG 964
Query: 2176 VRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHG--NSFFYADIMDNTIYRIRP 2349
+RGI E ++K +A++PIS G F V D H ++ ++ D+ N I R +
Sbjct: 965 IRGIPLEPSDKM--DALMPIS-------GTSFAVGIDFHAENDTIYWTDMGFNKISRAKR 1015
Query: 2350 DGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLI 2529
D ++ + ++ DWI+ +Y+ D+ N +EV ++ + R +I
Sbjct: 1016 DQTWKEDIITNGLGRVEGIAVDWIAGNIYWTDHGFNLIEVARLNGS--------FRYVII 1067
Query: 2530 TE-LRDPVSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAE 2706
++ L P S+ VHP KGLLF+ E + I + +DG V+ + + P+ ++ID+ E
Sbjct: 1068 SQGLDQPRSIAVHPEKGLLFWTEWGQMPCIGKARLDGSEKVVLVSMGIAWPNGISIDYEE 1127
Query: 2707 NRLCWGDTLLKTISCMDFD--GKNVVKLDIDNPIPVAITIMNEYIYYVHQRPY--SIRRV 2874
N+L W D I +D + G + L N ++ YIY+ + S+RR
Sbjct: 1128 NKLYWCDARTDKIERIDLETGGNREMVLSGSNVDMFSVAXFGAYIYWSDRAHANGSVRRG 1187
Query: 2875 HKKNGGGSKIVRE---FGADERSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPS 3045
HK + + +R E IF+ N D+ C QLC
Sbjct: 1188 HKNDATETITMRTGLGVNLKEVKIFNRVREKGTNVCARDN--------GGCKQLCL---- 1235
Query: 3046 ESHPNELEAKCACRQGFM 3099
+ CAC G++
Sbjct: 1236 --YRGNSRRTCACAHGYL 1251
Score = 155 bits (391), Expect = 4e-35
Identities = 114/376 (30%), Positives = 179/376 (47%), Gaps = 10/376 (2%)
Frame = +1
Query: 9772 ISDQKSCHNVNECYEGISGCSQKCDDKIGSYK-CGCVDGYQLSSDDHSCKRTEMEPEPFF 9948
+ D+++ N C GCSQ C + + C C GY L + SC+ E F
Sbjct: 902 VYDKEAQQGSNSCQLNNGGCSQLCLPTSETTRTCMCTVGYYLQKNRMSCQGIES-----F 956
Query: 9949 LLANKHY-IRKISID-GNKYE--LAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLD 10116
L+ + H IR I ++ +K + + G V +D Y D G ++ R D
Sbjct: 957 LMYSVHEGIRGIPLEPSDKMDALMPISGTSFAVGIDFHAENDTIYWTDMGFNKISRAKRD 1016
Query: 10117 EMDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRI 10296
+ + E ++ + + EGIAVDW+ +Y + I V L+G F +I +
Sbjct: 1017 Q-----TWKEDIITNGLGRVEGIAVDWIAGNIYWTDHGFNLIEVARLNGSFRYVIISQGL 1071
Query: 10297 QQPKAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYF 10476
QP++I VHP KG LF+TEW P IG+ LDGS ++ L + WPN I+IDY
Sbjct: 1072 DQPRSIAVHPEKGLLFWTEWGQMPCIGKARLDGSEKV-----VLVSMGIAWPNGISIDYE 1126
Query: 10477 SDRLFWGDAHLNEIGFMDFDGNGRRHIPAQRTS-HVSSMVVFDDYLYWAD-WNLREVLRC 10650
++L+W DA ++I +D + G R + ++ + S+ F Y+YW+D + +R
Sbjct: 1127 ENKLYWCDARTDKIERIDLETGGNREMVLSGSNVDMFSVAXFGAYIYWSDRAHANGSVRR 1186
Query: 10651 DKWTGKNETILKKT---VQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYT 10821
ETI +T V L +++I + +R+ N C +NGGC LCL G + T
Sbjct: 1187 GHKNDATETITMRTGLGVNL-KEVKIFNRVREKG-TNVCARDNGGCKQLCLY-RGNSRRT 1243
Query: 10822 CSCPDQFVLLSDQKTC 10869
C+C + L D TC
Sbjct: 1244 CACAHGY-LAEDGVTC 1258
Score = 149 bits (377), Expect = 1e-33
Identities = 145/560 (25%), Positives = 226/560 (39%), Gaps = 39/560 (6%)
Frame = +1
Query: 9733 GYKCDCFE------GFAIDISDQKSCHNVNE-----CYEGISGCSQKCDDKIGSYK-CGC 9876
G+K D E G +++ + K + V E C GC Q C + S + C C
Sbjct: 1187 GHKNDATETITMRTGLGVNLKEVKIFNRVREKGTNVCARDNGGCKQLCLYRGNSRRTCAC 1246
Query: 9877 VDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNK--------YELAAQGFDNV 10032
GY L+ D +C R E + L + + ++ I + YE + F NV
Sbjct: 1247 AHGY-LAEDGVTCLRHE----GYLLYSGRTILKSIHLSDETNLNSPIRPYE-NPRYFKNV 1300
Query: 10033 VSLDIDLTEKKA-----YLIDQ--GKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIAV 10191
++L D +++ + D G ++L++ + ++ V+ NV EG+A
Sbjct: 1301 IALAFDYNQRRKGTNRIFYSDAHFGNIQLIKDNWEDRQ--------VIVENVGSVEGLAY 1352
Query: 10192 DWVGRKLYMLNRQERSIRVCELD----GRFCKTLI--RDRIQQPKAIVVHPGKGYLFFTE 10353
LY + SI +D G F + + P + + + +F+T
Sbjct: 1353 HRAWDTLYWTSSTTSSITRHTVDQTRPGAFDREAVITMSEDDHPHVLALDECQNLMFWTN 1412
Query: 10354 WSLQ-PYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMD 10530
W+ Q P I R L G + D+ PN + IDY +++L++ D L +I +
Sbjct: 1413 WNEQHPSIMRSTLTGKNAQV-----VVSTDILTPNGLTIDYRAEKLYFSDGSLGKIERCE 1467
Query: 10531 FDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTV-QLPN 10707
+DG+ R I S+ V+D+Y++W+DW R +LR +K+TG + IL+ + P
Sbjct: 1468 YDGSQRHVIVKSGPGTFLSLAVYDNYIFWSDWGRRAILRSNKYTGGDTKILRSDIPHQPM 1527
Query: 10708 DLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTCEPNCT- 10884
+ V +PC NGGC LCL+ G CSC +LL D + N +
Sbjct: 1528 GIIAVANDTNSCELSPCALLNGGCHDLCLLTPNGR-VNCSCRGDRILLEDNRCVTKNSSC 1586
Query: 10885 --ERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRP 11058
+F CG + +CI CDG P C+D SDE C R C G C N C
Sbjct: 1587 NAYSEFECG--NGECIDYQLTCDGIPHCKDKSDEK-LLYCENRSCRRGFKPCYNRRCIPH 1643
Query: 11059 FQIXXXXXXXXXXXXEQNCD-KACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEADTL 11235
++ E +C C F+C A G CIPR SDE +
Sbjct: 1644 GKLCDGENDCGDNSDELDCKVSTCATVEFRC-ADGTCIPRSARCNQNIDCADASDEKN-- 1700
Query: 11236 CMSAERNCTAEEFRCNNNKC 11295
CNN C
Sbjct: 1701 --------------CNNTDC 1706
Score = 134 bits (336), Expect = 8e-29
Identities = 104/375 (27%), Positives = 166/375 (43%), Gaps = 9/375 (2%)
Frame = +1
Query: 9775 SDQKSCHNVNECYEGISGCSQKC-DDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFL 9951
S Q N +G CS C + S C C +LSSD +C + F L
Sbjct: 598 SRQPQAPNPCAANDGKGPCSHMCLINHNRSAACACPHLMKLSSDKKTCYGMKK----FLL 653
Query: 9952 LANKHYIRKISIDGNKYEL----AAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDE 10119
A + IR + ID + D+V +D D +E++ Y D + R ++
Sbjct: 654 YARRSEIRGVDIDNPYFNFITAFTVPDIDDVTVIDFDASEERLYWTDIKTQTIKRAFING 713
Query: 10120 MDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQ--ERSIRVCELDGRFCKTLIRDR 10293
+ ETV+ ++ G+AVDWV R LY ++ + E I V LDG KT I
Sbjct: 714 -----TGLETVISRDIQSIRGLAVDWVSRNLYWISSEFDETQINVARLDGSL-KTSIIHG 767
Query: 10294 IQQPKAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDY 10473
I +P+ + HP +G L++T+ + I +DGS K+ + P ++IDY
Sbjct: 768 IDKPQCLAAHPVRGKLYWTDGNT---INMANMDGSNS------KILFQNQKEPVGLSIDY 818
Query: 10474 FSDRLFWGDAHLNEIGFMDFDGNGRRHIPAQRT--SHVSSMVVFDDYLYWADWNLREVLR 10647
++L+W + I + DG I + + + +++ + D L+WAD NL ++
Sbjct: 819 VENKLYWISSGNGTINRCNLDGGNLEVIESMKEELTKATALTIMDKKLWWADQNLAQLGT 878
Query: 10648 CDKWTGKNETILKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCS 10827
C K G+N TIL+ +++ Q N C NNGGCS LCL TC
Sbjct: 879 CSKRDGRNPTILRNKTSGVVHMKVYDKEAQQG-SNSCQLNNGGCSQLCL-PTSETTRTCM 936
Query: 10828 CPDQFVLLSDQKTCE 10872
C + L ++ +C+
Sbjct: 937 CTVGYYLQKNRMSCQ 951
Score = 125 bits (315), Expect = 2e-26
Identities = 100/369 (27%), Positives = 141/369 (38%), Gaps = 32/369 (8%)
Frame = +1
Query: 10879 CTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRIC-PVGEFQCTNHNCTR 11055
C QF+CG + +CIP+ W CD E DC D +DE C C P+ +F C + C
Sbjct: 3 CQVDQFSCG--NGRCIPRAWLCDREDDCGDQTDEMAS--CEFPTCEPLTQFVCKSGRCIS 58
Query: 11056 PFQIXXXXXXXXXXXXEQNCDKACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEADTL 11235
E C +C F+C ++GRCIP + SDEA
Sbjct: 59 SKWHCDSDDDCGDGSDEVGCVHSCFDNQFRC-SSGRCIPGHWACDGDNDCGDFSDEAQIN 117
Query: 11236 CMSAE----RNCTAEEFRCN-NNKCIAKAWRXXXXXXXXXXXXETPECAQIECKKGWTRC 11400
C E C EF+C+ + C+ WR
Sbjct: 118 CTKEEIHSPAGCNGNEFQCHPDGNCVPDLWR----------------------------- 148
Query: 11401 SSSYRCIPNWAFCNGQDDCRDNSDED--KQRCPTCDDVGEFRCATSGKCIPRRWMCDTEN 11574
C+G+ DC D SDE CD +F C ++G+CI + W+CD +
Sbjct: 149 ------------CDGEKDCEDGSDEKGCNGTIRLCDHKTKFSCWSTGRCINKAWVCDGDI 196
Query: 11575 DCGDNSDELDAS---CGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDE----SQ 11733
DC D SDE D CG PC+ + C+ K+C+G C DG DE +
Sbjct: 197 DCEDQSDEDDCDSFLCGPPKHPCAN-----DTSVCLQPEKLCNGKKDCPDGSDEGYLCDE 251
Query: 11734 CTLRR--------CLPGHR---QCDDGTCI-AEHKWCDRKKDCPNAADELHCEDVSRR-- 11871
C+L +PG C +G + ++K C+ C N L C V +
Sbjct: 252 CSLNNGGCSNHCSVVPGRGIVCSCPEGLQLNKDNKTCEIVDYCSN---HLKCSQVCEQHK 308
Query: 11872 ---TCSPFE 11889
CS +E
Sbjct: 309 HTVKCSCYE 317
Score = 108 bits (269), Expect = 5e-21
Identities = 59/157 (37%), Positives = 76/157 (47%), Gaps = 5/157 (3%)
Frame = +1
Query: 9229 DGDVTCAGGEDE---STELCKTEKKECNK-GEFRCSNQHCIHSTWECDGDNDCLDGSDEH 9396
+G V C+ D C T+ CN EF C N CI CDG C D SDE
Sbjct: 1560 NGRVNCSCRGDRILLEDNRCVTKNSSCNAYSEFECGNGECIDYQLTCDGIPHCKDKSDEK 1619
Query: 9397 A-NCTYSSCQPDFFQCANHKCVPNSWKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQ 9573
C SC+ F C N +C+P+ CDG +DC D SDE DC K S C+ +
Sbjct: 1620 LLYCENRSCRRGFKPCYNRRCIPHGKLCDGENDCGDNSDELDC--------KVSTCATVE 1671
Query: 9574 FQCTSGECIDDAKVCDRNFDCTDRSDESSLCFIDECS 9684
F+C G CI + C++N DC D SDE + C +C+
Sbjct: 1672 FRCADGTCIPRSARCNQNIDCADASDEKN-CNNTDCT 1707
Score = 99.4 bits (246), Expect = 2e-18
Identities = 66/218 (30%), Positives = 98/218 (44%), Gaps = 10/218 (4%)
Frame = +1
Query: 3088 QGFMINKENNHSCQKDPAEKIEQLCSSNSTQFQCKNGRCIPKEWKCDGENDCLDESDEID 3267
+ ++ ++E++ Q D E TQF CK+GRCI +W CD ++DC D SDE+
Sbjct: 18 RAWLCDREDDCGDQTDEMASCEFPTCEPLTQFVCKSGRCISSKWHCDSDDDCGDGSDEVG 77
Query: 3268 EKGDKCFHETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYC--KDGQKPV-C 3438
C H C +N +C ++ +CIP C ++ P C
Sbjct: 78 -----CVH--SCFDNQFRC-SSGRCIPGHWACDGDNDCGDFSDEAQINCTKEEIHSPAGC 129
Query: 3439 AAKKFQC-DNHRCIPEQWKXXXXXXXXXXXXEK-----LEMCGNATCAANQFSC-ANGRC 3597
+FQC + C+P+ W+ EK + +C + T +FSC + GRC
Sbjct: 130 NGNEFQCHPDGNCVPDLWRCDGEKDCEDGSDEKGCNGTIRLCDHKT----KFSCWSTGRC 185
Query: 3598 IPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCAN 3711
I W+CDGD DC D +DED C C + CAN
Sbjct: 186 INKAWVCDGDIDCEDQSDEDD--CDSFLCGPPKHPCAN 221
Score = 95.5 bits (236), Expect = 3e-17
Identities = 56/166 (33%), Positives = 73/166 (43%)
Frame = +1
Query: 11254 NCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXETPECAQIECKKGWTRCSSSYRCIPNWA 11433
+C + +N+C+ K ++ EC G CI
Sbjct: 1566 SCRGDRILLEDNRCVTK-------------NSSCNAYSEFECGNG--------ECIDYQL 1604
Query: 11434 FCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASC 11613
C+G C+D SDE C F+ + +CIP +CD ENDCGDNSDELD C
Sbjct: 1605 TCDGIPHCKDKSDEKLLYCENRSCRRGFKPCYNRRCIPHGKLCDGENDCGDNSDELD--C 1662
Query: 11614 GGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTLRRC 11751
+T C+ EFRC DG CIP S C+ I C+D DE C C
Sbjct: 1663 KVST--CATVEFRCADGTCIPRSARCNQNIDCADASDEKNCNNTDC 1706
Score = 95.5 bits (236), Expect = 3e-17
Identities = 64/182 (35%), Positives = 76/182 (41%)
Frame = +1
Query: 8452 CADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCNHIDDCGDGSDELDCPSAVACAEG 8631
C D PN SC D L + RC+ CN A
Sbjct: 1551 CHDLCLLTPNGRVNCSCRGDRILLEDNRCVTKNSSCN--------------------AYS 1590
Query: 8632 TFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPGLPIDCRGVKVRCPNTNICIQPAD 8811
F C NG CI+ CDG C D+ SDE L C CR C N CI
Sbjct: 1591 EFECGNGECIDYQLTCDGIPHCKDK--SDEKLLYCENR--SCRRGFKPCYNRR-CIPHGK 1645
Query: 8812 LCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNC 8991
LCDG +DCGD +DE L C CA RC G CIP + +C+ + DC+D DE + N
Sbjct: 1646 LCDGENDCGDNSDE--LDCKVSTCATVEFRCADGTCIPRSARCNQNIDCADASDEKNCNN 1703
Query: 8992 TD 8997
TD
Sbjct: 1704 TD 1705
Score = 92.4 bits (228), Expect = 3e-16
Identities = 52/149 (34%), Positives = 74/149 (48%), Gaps = 6/149 (4%)
Frame = +1
Query: 478 DGKYDCRDLSD----EKDSCSRNHTACFQY-QFRCADKTQCIQKSWVCDGSKDCADGSDE 642
+G+ +C D E + C +++C Y +F C + +CI CDG C D SDE
Sbjct: 1560 NGRVNCSCRGDRILLEDNRCVTKNSSCNAYSEFECGNG-ECIDYQLTCDGIPHCKDKSDE 1618
Query: 643 PDT-CEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTG 819
CE + C C N+RC P CD +DCGDNSDE +C C ++ C G
Sbjct: 1619 KLLYCENRSCRRGFKPCYNRRCIPHGKLCDGENDCGDNSDELDCKVSTCATVEFRC-ADG 1677
Query: 820 HCIDQLKLCDGSKDCADGADEQQCSQNLC 906
CI + C+ + DCAD +DE+ C+ C
Sbjct: 1678 TCIPRSARCNQNIDCADASDEKNCNNTDC 1706
Score = 91.7 bits (226), Expect = 5e-16
Identities = 51/147 (34%), Positives = 69/147 (46%), Gaps = 7/147 (4%)
Frame = +1
Query: 11440 NGQDDCRDNSDE---DKQRCPT----CDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDE 11598
NG+ +C D + RC T C+ EF C +G+CI + CD C D SDE
Sbjct: 1560 NGRVNCSCRGDRILLEDNRCVTKNSSCNAYSEFECG-NGECIDYQLTCDGIPHCKDKSDE 1618
Query: 11599 LDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQCDD 11778
C R C C + +CIP K+CDG C D DE C + C +C D
Sbjct: 1619 KLLYC--ENRSCRRGFKPCYNRRCIPHGKLCDGENDCGDNSDELDCKVSTCATVEFRCAD 1676
Query: 11779 GTCIAEHKWCDRKKDCPNAADELHCED 11859
GTCI C++ DC +A+DE +C +
Sbjct: 1677 GTCIPRSARCNQNIDCADASDEKNCNN 1703
Score = 77.4 bits (189), Expect = 9e-12
Identities = 56/193 (29%), Positives = 85/193 (44%), Gaps = 5/193 (2%)
Frame = +1
Query: 11722 DESQCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCED----VSRRTCSPF- 11886
D + C L C + C D + + + +C D + ED +C+ +
Sbjct: 1535 DTNSCELSPCALLNGGCHDLCLLTPNG----RVNCSCRGDRILLEDNRCVTKNSSCNAYS 1590
Query: 11887 EFECANSVCIPRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCN 12066
EFEC N CI + SDE C + C F+ ++R C+ +LC+
Sbjct: 1591 EFECGNGECIDYQLTCDGIPHCKDKSDEKLLYCENRSCRRG--FKPCYNRRCIPHGKLCD 1648
Query: 12067 GFNDCGPNDFSDEHLSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEIG 12246
G NDCG N SDE S+ C++ +F+CA+G C+ + C++ DC DASDE
Sbjct: 1649 GENDCGDN--SDELDCKVST------CATVEFRCADGTCIPRSARCNQNIDCADASDEKN 1700
Query: 12247 CSKHGGKTSCEAF 12285
C+ T C F
Sbjct: 1701 CN----NTDCTHF 1709
Score = 72.8 bits (177), Expect = 2e-10
Identities = 52/200 (26%), Positives = 71/200 (35%), Gaps = 32/200 (16%)
Frame = +1
Query: 9415 SCQPDFFQCANHKCVPNSWKCDGNDDCEDGSDE--------------------------- 9513
+CQ D F C N +C+P +W CD DDC D +DE
Sbjct: 2 TCQVDQFSCGNGRCIPRAWLCDREDDCGDQTDEMASCEFPTCEPLTQFVCKSGRCISSKW 61
Query: 9514 -----KDCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLCFIDE 9678
DC S C + QF+C+SG CI CD + DC D SDE+ +
Sbjct: 62 HCDSDDDCGDGSDEVGCVHSCFDNQFRCSSGRCIPGHWACDGDNDCGDFSDEAQI----- 116
Query: 9679 CSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNECYEGISGCSQKCDDKIG 9858
C +I C ++ CH C + C + D + G
Sbjct: 117 -----------NCTKEEIHSPAGC-------NGNEFQCHPDGNCVPDLWRCDGEKDCEDG 158
Query: 9859 SYKCGCVDGYQLSSDDHSCK 9918
S + GC +L DH K
Sbjct: 159 SDEKGCNGTIRLC--DHKTK 176
Score = 67.8 bits (164), Expect = 7e-09
Identities = 34/92 (36%), Positives = 46/92 (49%)
Frame = +1
Query: 8794 CIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWD 8973
CI CDG C DK+DE L+C N+ C + + C + RCIP CDG+NDC D D
Sbjct: 1599 CIDYQLTCDGIPHCKDKSDEKLLYCENRSCRRGFKPCYNRRCIPHGKLCDGENDCGDNSD 1658
Query: 8974 ETHTNCTDTAGKKICVGDYLFQCDNLKCISRA 9069
E + A + F+C + CI R+
Sbjct: 1659 ELDCKVSTCATVE-------FRCADGTCIPRS 1683
Score = 64.3 bits (155), Expect = 8e-08
Identities = 51/168 (30%), Positives = 72/168 (42%), Gaps = 19/168 (11%)
Frame = +1
Query: 142 TASSVCNE-NDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQ--WQCDTYTW 312
T +S CN ++F C +G+CI + PH KSD+ C+ +
Sbjct: 1581 TKNSSCNAYSEFECGNGECIDYQ------------LTCDGIPHCKDKSDEKLLYCENRSC 1628
Query: 313 -------HSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSK 471
++ CI + CD DC D SDE DC ST C++ F CADG C S
Sbjct: 1629 RRGFKPCYNRRCIPHGKLCDGENDCGDNSDELDCKVST--CATVE-FRCADG-TCIPRSA 1684
Query: 472 KCDGKYDCRDLSDEKDSCSRNHTACFQYQ---------FRCADKTQCI 588
+C+ DC D SDEK+ N+T C + RC + C+
Sbjct: 1685 RCNQNIDCADASDEKNC---NNTDCTHFYKLGVKTTGFIRCNSTSLCV 1729
Score = 61.2 bits (147), Expect = 7e-07
Identities = 59/214 (27%), Positives = 73/214 (33%), Gaps = 10/214 (4%)
Frame = +1
Query: 8809 DLC----DGYDDCGDKAD-----ENQLFCMNQQC-AQHYVRCPSGRCIPETWQCDGDNDC 8958
DLC +G +C + D +N+ N C A C +G CI CDG C
Sbjct: 1553 DLCLLTPNGRVNCSCRGDRILLEDNRCVTKNSSCNAYSEFECGNGECIDYQLTCDGIPHC 1612
Query: 8959 SDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXXXXXXHSRHGCGN 9138
D DE L C+N C R F C N
Sbjct: 1613 KDKSDEK-----------------LLYCENRSC-RRGF-----------------KPCYN 1637
Query: 9139 RTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECNKGEFR 9318
R CIP LCDG+ C DE CK C EFR
Sbjct: 1638 R--------------------RCIPHGKLCDGENDCGDNSDELD--CKV--STCATVEFR 1673
Query: 9319 CSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSC 9420
C++ CI + C+ + DC D SDE NC + C
Sbjct: 1674 CADGTCIPRSARCNQNIDCADASDE-KNCNNTDC 1706
Score = 61.2 bits (147), Expect = 7e-07
Identities = 83/346 (23%), Positives = 110/346 (30%), Gaps = 27/346 (7%)
Frame = +1
Query: 10756 CGDNNG--GCSHLCLIGAGGNGYTCSC----PDQFVLLSDQKT------CEPNCTERQF- 10896
CGD + GC H C N + CS P + D + NCT+ +
Sbjct: 69 CGDGSDEVGCVHSCF----DNQFRCSSGRCIPGHWACDGDNDCGDFSDEAQINCTKEEIH 124
Query: 10897 ---ACGGD------DAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNC 11049
C G+ D C+P LW CDGE DC DGSDE G C I
Sbjct: 125 SPAGCNGNEFQCHPDGNCVPDLWRCDGEKDCEDGSDEKG---CNGTI------------- 168
Query: 11050 TRPFQIXXXXXXXXXXXXEQNCDKACD-PWMFKCAATGRCIPRRFTXXXXXXXXXRSDEA 11226
+ CD F C +TGRCI + + +SDE
Sbjct: 169 -----------------------RLCDHKTKFSCWSTGRCINKAWVCDGDIDCEDQSDED 205
Query: 11227 DTLCMSAERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXETPECAQIECKKGWTRCSS 11406
D + F C K +T C Q E
Sbjct: 206 D-----------CDSFLCGPPK--------------HPCANDTSVCLQPE---------- 230
Query: 11407 SYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRW-MCDTENDCG 11583
CNG+ DC D SDE C C + C+ +P R +C
Sbjct: 231 --------KLCNGKKDCPDGSDEG-YLCDEC-SLNNGGCSNHCSVVPGRGIVCSCPEGLQ 280
Query: 11584 DNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCD---GTIQCS 11712
N D + C ++ N KC S+VC+ T++CS
Sbjct: 281 LNKD---------NKTCEIVDYCSNHLKC---SQVCEQHKHTVKCS 314
Score = 60.1 bits (144), Expect = 2e-06
Identities = 74/385 (19%), Positives = 148/385 (38%), Gaps = 5/385 (1%)
Frame = +1
Query: 12415 NNTCTQLCLNT-KGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSL 12591
N C+QLCL T + + C C Y + +G + +M + + + L
Sbjct: 918 NGGCSQLCLPTSETTRTCMCTVGYY-------LQKNRMSCQGIESFLMYSVHEGIRGIPL 970
Query: 12592 HGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERTIYRSAIANGNQSHEGQKLD 12771
S ++ + +YW D I R+ + + K D
Sbjct: 971 EPS--DKMDALMPISGTSFAVGIDFHAENDTIYWTDMGFNKISRA------KRDQTWKED 1022
Query: 12772 VDFAAMGVVPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLP 12951
+ +G V IAVD+ GN++ N+ I V
Sbjct: 1023 IITNGLGRVE-GIAVDWIAGNIYWTDHGFNL-----------------------IEVARL 1058
Query: 12952 DGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSP 13131
+G + I++ L QP ++ P G + +++ G I A +DG+ + ++V + P
Sbjct: 1059 NGSFRYVIISQGLDQPRSIAVHPEKGLLFWTEWGQMPCIGKARLDGSEKVVLVSMGIAWP 1118
Query: 13132 TSMAIDEGKGNRIYWVDPKYRRVDAVNID-GSERTTVVHDRHIP-YAVDVFENHIYWLSR 13305
++ID + N++YW D + +++ ++++ G R V+ ++ ++V F +IYW R
Sbjct: 1119 NGISIDY-EENKLYWCDARTDKIERIDLETGGNREMVLSGSNVDMFSVAXFGAYIYWSDR 1177
Query: 13306 ESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCER--AQCSHLCVSL 13479
V+ + G ++ + + + ++ + C R C LC+
Sbjct: 1178 AHANGSVRRGHKNDATETITMRTGLGVNLKEVKIFNRVREKGTNVCARDNGGCKQLCLYR 1237
Query: 13480 PSTGFACLCPDGIVPQLDGSCATQH 13554
++ C C G + + DG +H
Sbjct: 1238 GNSRRTCACAHGYLAE-DGVTCLRH 1261
Score = 58.9 bits (141), Expect = 3e-06
Identities = 37/112 (33%), Positives = 48/112 (42%), Gaps = 9/112 (8%)
Frame = +1
Query: 607 DGSKDCADGSD----EPDTCEFKKCTAN---EFQCKNKRCQPRKFRCDYYDDCGDNSDED 765
+G +C+ D E + C K + N EF+C N C + CD C D SDE
Sbjct: 1560 NGRVNCSCRGDRILLEDNRCVTKNSSCNAYSEFECGNGECIDYQLTCDGIPHCKDKSDEK 1619
Query: 766 --ECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSL 915
C C G C CI KLCDG DC D +DE C + C ++
Sbjct: 1620 LLYCENRSCRRGFKPCYNR-RCIPHGKLCDGENDCGDNSDELDCKVSTCATV 1670
Score = 57.8 bits (138), Expect = 8e-06
Identities = 50/215 (23%), Positives = 92/215 (42%), Gaps = 10/215 (4%)
Frame = +1
Query: 13057 HAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTT 13236
H I + + G + Q++V + +P + ID + ++Y+ D +++ DGS+R
Sbjct: 1417 HPSIMRSTLTGKNAQVVVSTDILTPNGLTIDY-RAEKLYFSDGSLGKIERCEYDGSQRHV 1475
Query: 13237 VVHDRHIPY-AVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYA 13413
+V + ++ V++N+I+W + + +K+ G +L SD+ H A
Sbjct: 1476 IVKSGPGTFLSLAVYDNYIFWSDWGRRAILRSNKYTGGDTKILRSDIP--HQPMGIIAVA 1533
Query: 13414 KDTQR-TVSGCE--RAQCSHLCVSLPSTGFACLCPDGIVPQLDGSCATQHVEALTMPKQC 13584
DT +S C C LC+ P+ C C + D C T++ + +
Sbjct: 1534 NDTNSCELSPCALLNGGCHDLCLLTPNGRVNCSCRGDRILLEDNRCVTKN-SSCNAYSEF 1592
Query: 13585 KCTNGG----KCRLDG--SCECTSDFEGDQCEKES 13671
+C NG + DG C+ SD + CE S
Sbjct: 1593 ECGNGECIDYQLTCDGIPHCKDKSDEKLLYCENRS 1627
Score = 57.0 bits (136), Expect = 1e-05
Identities = 67/304 (22%), Positives = 123/304 (40%), Gaps = 5/304 (1%)
Frame = +1
Query: 12676 KELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAVS 12855
+E +YW D +TI R+ I NG D+ +AVD+ + NL+ + S
Sbjct: 693 EERLYWTDIKTQTIKRAFI-NGTGLETVISRDIQSIR------GLAVDWVSRNLYWIS-S 744
Query: 12856 ENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRI 13035
E E + AR DG I+ G + +P L P G++
Sbjct: 745 EFDETQINVARL--------------------DGSLKTSIIHG-IDKPQCLAAHPVRGKL 783
Query: 13036 CYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNI 13215
++D I A+MDG++ +I+ ++ P ++ID + N++YW+ ++ N+
Sbjct: 784 YWTDGNT---INMANMDGSNSKILFQNQK-EPVGLSIDYVE-NKLYWISSGNGTINRCNL 838
Query: 13216 DGSERTTVVHDRHI---PYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGH 13386
DG + + A+ + + ++W + L K ++L +
Sbjct: 839 DGGNLEVIESMKEELTKATALTIMDKKLWWADQNLAQLGTCSKRDGRNPTILRNKTSGVV 898
Query: 13387 TVRVSQKYAKDTQRTVSGCE--RAQCSHLCVSLPSTGFACLCPDGIVPQLDGSCATQHVE 13560
++V Y K+ Q+ + C+ CS LC+ T C+C G Q + Q +E
Sbjct: 899 HMKV---YDKEAQQGSNSCQLNNGGCSQLCLPTSETTRTCMCTVGYYLQ-KNRMSCQGIE 954
Query: 13561 ALTM 13572
+ M
Sbjct: 955 SFLM 958
>gi|50748119|ref|XP_421114.1| PREDICTED: similar to Low-density
lipoprotein receptor-related protein 4 precursor
(Multiple epidermal growth factor-like domains 7) [Gallus
gallus]
Length = 2222
Score = 708 bits (1827), Expect = 0.0
Identities = 501/1753 (28%), Positives = 818/1753 (46%), Gaps = 26/1753 (1%)
Frame = +1
Query: 3109 ENNHSCQKDPAEKIEQLCSSNSTQFQCKNGRCIPKEWKCDGENDCLDESDEIDEKGDKCF 3288
+ ++ C E L + + F C NG+CI + W CDG+NDC D+SDE D C
Sbjct: 349 DGDNDCGDHSDEDGCMLPTCSPLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQD-----CP 403
Query: 3289 HETECAENTIKCRNTKKCIPAQXXXXXXXXXXXX----XXXXVKYCKDGQKPVCAAKKFQ 3456
+ + + + +PAQ + + C +F
Sbjct: 404 SSPFKPSSLRREKGAVRMLPAQTAIALKAGLSAACKVLSSEELPWKAASPPRECEEDEFS 463
Query: 3457 CDNHRCIPEQWKXXXXXXXXXXXXEKLEMCGNATCAANQFSCANGRCIPIYWLCDGDNDC 3636
C N CI W E+ +M C+ +F C++G CI +W CDGD DC
Sbjct: 464 CQNGYCIRSLWHCDGDNDCGDNSDEQCDM---RKCSEKEFRCSDGSCIAEHWFCDGDTDC 520
Query: 3637 YDGTDEDK--ERCPPVQCSALQFRCANGRQCVPLRNHXXXXXXXXXXXXXXXXAVTAESC 3810
DG+DE+ P CS +F+CA GR C+ L + + + C
Sbjct: 521 KDGSDEENCPSDVPAATCSLEEFQCAYGR-CI-LDIYHCDGDDDCGDWSDESDCSSHQPC 578
Query: 3811 TPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKCGNGRCILNNW 3990
+F C +SGLCI A W+ SDE CT+ C++DQF+C +GRC+ +W
Sbjct: 579 RSGEFMC-NSGLCINAGWRCDGDSDCDDQSDERN--CTTS-MCTADQFRCKSGRCVRLSW 634
Query: 3991 LCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGT 4170
CDGE+DC D SDE + C+ + +C + C N + CI +LC+G C G+
Sbjct: 635 RCDGEDDCSDNSDEEN---CENT-GTPQCAPDQFLCGNGR--CIGQRKLCNGANDCGDGS 688
Query: 4171 DEGG------RCARDLCSADRAGCSFKCHNSPNGPICSCPFGEQLVNKTK-CEPENECLD 4329
DE R + C+ + GC+ KC C+C G +L+ + C+ NEC +
Sbjct: 689 DESPHQNCRPRTGEENCNVNNGGCAQKCQMVRGMVQCTCHTGYRLLEDGRSCQDVNECAE 748
Query: 4330 SSSCSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDN 4509
CSQ C + + GF C C++GYEL DKR+CK + + +NR I
Sbjct: 749 EGYCSQGCTNSEGGFQCWCEQGYELRPDKRSCKALG--PEPVLLFANRIDIRQVLPHRSE 806
Query: 4510 WHTFGAIVENAIALAWDSLTDRIYWSDIREKKILSANRNGTNATVFIADGLDITEGIALD 4689
+ +ENAIAL + + ++WSD+ +I+ AN NG+N ++ GL+ G+A+D
Sbjct: 807 YTLLLNNLENAIALDFHHSKELVFWSDVTLDRIMRANLNGSNVEEVVSTGLESPGGLAID 866
Query: 4690 WVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQNPC 4869
W+ LYW DS + IEVANL D R +L+ QN+ +PR IA+ P +G ++WTDWG P
Sbjct: 867 WIHDKLYWTDSGTSRIEVANL-DGTHRKVLLWQNLEKPRAIALHPMEGTIYWTDWGNTPR 925
Query: 4870 IERASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLAS 5049
IE ++MDG++R+II T ++WPN + +DY R+Y+ D+K I+ + DG R V+
Sbjct: 926 IEYSNMDGSNRRIIADTHLFWPNGLTIDYAGHRMYWVDAKHHVIERADLDGRNRKAVI-- 983
Query: 5050 SKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQ 5229
S+ + HP A+ +FED +Y++D + + K+ G E + + + +HP Q
Sbjct: 984 SQGLPHPFAITVFEDSLYWTDWHTKSINSANKF-TGKNQEIIRNKLHFPMDIHTLHPQRQ 1042
Query: 5230 PVIKNNPCSTN--PCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNV 5403
P +N C N C+HLCL ++K+ +TC CP G + S C FL+ ++ ++
Sbjct: 1043 PAGRNR-CGANNGGCTHLCLPSSKD-YTCACPTGFR-KTSSHACAQSLDKFLLFARRMDI 1099
Query: 5404 FGIEMNSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSA 5583
I ++ + ++PL+ + +A +D+ + ++ ++TDS
Sbjct: 1100 RRISFDTDDLSD-----DVIPLADVRSAVALDWDSKDDYVY----------WTDVSTDS- 1143
Query: 5584 IYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVIL 5763
I R+ +G + + +++ A L DW L + T IE+ T G +I
Sbjct: 1144 ISRAKWDGSGQEVVVDTSLESPA-GLAIDWVTNKLYWTDAGTDRIEVSNTDGTMRTVLIW 1202
Query: 5764 SNDQSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELD 5943
N G+++W D G A+ K+ RAG+D SN LVI S++L +
Sbjct: 1203 EN------LDRPRDIVVDPVGGFMYWTDWG---ANPKIERAGMDASNRLVIISSNLTWPN 1253
Query: 5944 HIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAFD 6123
+AID + R+Y+++A I + DG +R ++ P GL YG+R+++ D
Sbjct: 1254 GLAIDYESQRLYWADAGMKTIEYASLDGSNRKVLIGSNLPHPFGLTLYGERIYWTDWQAK 1313
Query: 6124 SIEVATINGDSQPPQWTHFKKD-VENLANIKALQPRASSSGHPCHINNGNCDHICIPLMF 6300
SI+ A D + Q +D +ENL +I PC +NNG C H+C+
Sbjct: 1314 SIQSA----DRRTGQARETLQDNLENLMDIHVFHRHRPPVRTPCEVNNGGCSHLCLLAPL 1369
Query: 6301 AQ-RTCTCANG--YVKDGQTSCKLFDESFVIVATKTKVIGYPIDETQSKGVAMEPIGGLS 6471
+ +CTC G DG+T + V+V+ ++ T +A+
Sbjct: 1370 PKGYSCTCPTGINLQSDGKTC-----STDVVVS---------VNVTMKNTIAI------- 1408
Query: 6472 ITGVDYDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINYNM 6651
GVD +E K + + + I+ + S +I + G LT LA+D I +
Sbjct: 1409 --GVD-PHEGKVYW---SDSTLRKISRAALDGSKFEDII--TTGLLTTDGLAVDAIGRKI 1460
Query: 6652 YFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQRSF 6831
Y+ D IEV LDG+ RK+L+ ++P +IA+ Y+YW D G+ ++RS
Sbjct: 1461 YWT--DTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIALYHEMGYMYWTDWGENAKLERSG 1518
Query: 6832 LDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPELVRSDIASAA 7011
+DGS R V++S+ + P L VD A + W+DA + I G + S +
Sbjct: 1519 MDGSGRVVLISNNLGWPNGLAVDKAGSQLLWADAHTERIEAADLNGANRRTLLSPVQHPY 1578
Query: 7012 GVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRAS 7191
G+ L +YWTD + + RA +L V A+L + D+ +P
Sbjct: 1579 GLTLLDSYIYWTDWQTRSIHRADKDSGANVIL-----VRANLPGLMDIQAV-DRARPLGF 1632
Query: 7192 SPCQITDNLRKSPCTQLCFATPGTQTPTCSCARGVLKGR---TCE-EPDTYIMFSDGDKI 7359
+ C +R C+ LC P +C+C G+ R TC+ P+TY++FS I
Sbjct: 1633 NKC----GVRNGGCSHLCL--PHPTGFSCACPTGIQLKRDEQTCDSSPETYLLFSSRASI 1686
Query: 7360 IDVAIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAENP 7539
+++ D + P PE++N+ + D D ++Y+ + V +++ S N N
Sbjct: 1687 RRISL--DTSDHTDVHIPVPELNNVISLDYDSVDGKIYY---TDVFLDVIRRSDLNGSNM 1741
Query: 7540 RLVFGASKQPHAKEIRHISDMKLDWLTQKIYFT-TGRGG-KVMAIDTAGEHLSTIASGDW 7713
V G + ++ + +DW+ + +Y+T TGR +V +D + + S D
Sbjct: 1742 ETVIG-------QGLKTTDGLAVDWVARNLYWTDTGRNTVEVARLDGSSRKVLINNSLDE 1794
Query: 7714 TYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVDFR 7893
A+A+ P G LFW+D G+ +IER+NL G RK++++ + P + +D+
Sbjct: 1795 PRAIAVFPKKGYLFWTDWGHIA-------KIERANLDGSERKILINTDLGWPNGLTLDYD 1847
Query: 7894 NQKIYWADVNRLNIEVADYDGQNRKVIASGY-RAKSLDIWDRWLYMSDPLSNGVFRIDKE 8070
++IYW D + IE D +G+ R+V+ S +L DRW+Y +D + + R+DK
Sbjct: 1848 TRRIYWVDAHLDRIESCDLNGKLRQVLVSQVSHPFALTQQDRWIYWTDWQTKSIQRVDKY 1907
Query: 8071 SGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLCTVVADDI 8250
SG E V+++ + G + + +T C +NGGC LC A D
Sbjct: 1908 SGRNKETVLAN--VEGLMDIIVVSPQRQTGTNACG--------VNNGGCTHLCFARASDF 1957
Query: 8251 GLAASKVQCSCND 8289
C+C D
Sbjct: 1958 -------VCACPD 1963
Score = 468 bits (1205), Expect = e-129
Identities = 321/1017 (31%), Positives = 486/1017 (47%), Gaps = 24/1017 (2%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHSVSCIAE 336
C E++F C +G CIR+ W C +++C SCIAE
Sbjct: 457 CEEDEFSCQNGYCIRSLWHCDGDNDCGDNSDEQCDMRK-CSEKEFRCS-----DGSCIAE 510
Query: 337 YQRCDNITDCADGSDEKDCPAST--VDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSD 510
+ CD TDC DGSDE++CP+ CS + F CA GR D+ CDG DC D SD
Sbjct: 511 HWFCDGDTDCKDGSDEENCPSDVPAATCSLEE-FQCAYGRCILDIYH-CDGDDDCGDWSD 568
Query: 511 EKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQC 690
E D CS +H C +F C + CI W CDG DC D SDE + C CTA++F+C
Sbjct: 569 ESD-CS-SHQPCRSGEFMC-NSGLCINAGWRCDGDSDCDDQSDERN-CTTSMCTADQFRC 624
Query: 691 KNKRCQPRKFRCDYYDDCGDNSDEDEC---GEYRCPPGKWNCPGTGHCIDQLKLCDGSKD 861
K+ RC +RCD DDC DNSDE+ C G +C P ++ C G G CI Q KLC+G+ D
Sbjct: 625 KSGRCVRLSWRCDGEDDCSDNSDEENCENTGTPQCAPDQFLC-GNGRCIGQRKLCNGAND 683
Query: 862 CADGADEQQCSQNLCPSLG----------CQAGCHPSPHGGECTCPSGYKLDDRFHRTCS 1011
C DG+DE QN P G C C +CTC +GY+L + R+C
Sbjct: 684 CGDGSDESP-HQNCRPRTGEENCNVNNGGCAQKCQMVRGMVQCTCHTGYRLLED-GRSCQ 741
Query: 1012 DINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKL 1191
D+NECAE GYC Q C N GF C C E P K + C + + + L
Sbjct: 742 DVNECAEEGYCSQGCTNSEGGFQCWC-----EQGYELRPDKRS------CKALGPEPVLL 790
Query: 1192 FVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEG 1371
F A R + ++ P E L + E +DF + +FW+D A+++
Sbjct: 791 F-ANRIDIRQVLPHR-SEYTLLLNNLENAIALDFHHSKELVFWSDVTLDRIMRANLNG-- 846
Query: 1372 EISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPL 1551
S ++++ L P LA+DWI + LY +SG+ RI+V++ DG R VLL L P
Sbjct: 847 --SNVEEVVSTGLESPGGLAIDWIHDKLYWTDSGTSRIEVANLDGTHRKVLLWQNLEKPR 904
Query: 1552 DIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDP 1722
IAL P+ G +++T N ++E + MDG+NRR + +TH +G+ +D R+YWVD
Sbjct: 905 AIALHPMEGTIYWTDWGNTPRIEYSNMDGSNRRIIADTHLFWPNGLTIDYAGHRMYWVDA 964
Query: 1723 KVDRLESIDYQGNDRR-IVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTK 1899
K +E D G +R+ +++QG+ PHPF + +F+ LYWTDW + KF +
Sbjct: 965 KHHVIERADLDGRNRKAVISQGL---PHPFAITVFEDSLYWTDWHTKSINSANKFTGKNQ 1021
Query: 1900 LLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGV 2079
+ N + FPM I HP QP G++ C A N C +C+ S +
Sbjct: 1022 EIIRNKLH--FPMDIHTLHPQRQPA-GRNRCGA-------NNGGCTHLCLPSSKD----- 1066
Query: 2080 GYKCACPIGQKLVNGKRCIDSID-YLLFSSNKIVRGIFPEINEKALAEAVLPISPISQRR 2256
Y CACP G + + C S+D +LLF+ +R I + ++ L++ V+P++ +
Sbjct: 1067 -YTCACPTGFRKTSSHACAQSLDKFLLFARRMDIRRISFDTDD--LSDDVIPLADVRSA- 1122
Query: 2257 IGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWISKQLY 2436
++ D + ++ D+ ++I R + DG G V+ T + ++ DW++ +LY
Sbjct: 1123 ----VALDWDSKDDYVYWTDVSTDSISRAKWDGSGQEVVVDTSLESPAGLAIDWVTNKLY 1178
Query: 2437 YVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRD-PVSVVVHPWKGLLFYAEAMRPAA 2613
+ D + +EV + D +R LI E D P +VV P G +++ +
Sbjct: 1179 WTDAGTDRIEV--------SNTDGTMRTVLIWENLDRPRDIVVDPVGGFMYWTDWGANPK 1230
Query: 2614 IYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKN-VVKLDI 2790
I R +D N VI ++ L P+ +AID+ RL W D +KTI DG N V +
Sbjct: 1231 IERAGMDASNRLVIISSNLTWPNGLAIDYESQRLYWADAGMKTIEYASLDGSNRKVLIGS 1290
Query: 2791 DNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQ 2970
+ P P +T+ E IY+ + SI+ ++ G + +++ + ++ +
Sbjct: 1291 NLPHPFGLTLYGERIYWTDWQAKSIQSADRRTGQARETLQD---NLENLMDIHVFHRHRP 1347
Query: 2971 PIPDDSREHPCRASQ--CTQLCFATPSESHPNELEAKCACRQGFMINKENNHSCQKD 3135
P+ PC + C+ LC P C C G + + +C D
Sbjct: 1348 PV-----RTPCEVNNGGCSHLCLLAPLPK-----GYSCTCPTGINLQSDGK-TCSTD 1393
Score = 465 bits (1197), Expect = e-128
Identities = 281/838 (33%), Positives = 399/838 (47%), Gaps = 54/838 (6%)
Frame = +1
Query: 8536 CIDSAKKCNHIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVS 8715
CI + +C+ +DCGD SDE C C+ F C NG CI ++ VCDG NDC D+ S
Sbjct: 341 CIPAQWQCDGDNDCGDHSDEDGC-MLPTCSPLDFHCDNGKCIRRSWVCDGDNDCEDD--S 397
Query: 8716 DESLATCPGLPI------------------------------------------------ 8751
DE CP P
Sbjct: 398 DEQ--DCPSSPFKPSSLRREKGAVRMLPAQTAIALKAGLSAACKVLSSEELPWKAASPPR 455
Query: 8752 DCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCIPET 8931
+C + C N CI+ CDG +DCGD +DE C ++C++ RC G CI E
Sbjct: 456 ECEEDEFSCQN-GYCIRSLWHCDGDNDCGDNSDEQ---CDMRKCSEKEFRCSDGSCIAEH 511
Query: 8932 WQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXXXXX 9111
W CDGD DC DG DE NC
Sbjct: 512 WFCDGDTDCKDGSDEE--NCPSDVPAA--------------------------------- 536
Query: 9112 XHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEK 9291
TC+ +EF C CI + CDGD C DES C + +
Sbjct: 537 ----------TCSLEEFQCAYG--------RCILDIYHCDGDDDCGDWSDESD--CSSHQ 576
Query: 9292 KECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCANHKCVPNSW 9471
C GEF C++ CI++ W CDGD+DC D SDE NCT S C D F+C + +CV SW
Sbjct: 577 P-CRSGEFMCNSGLCINAGWRCDGDSDCDDQSDER-NCTTSMCTADQFRCKSGRCVRLSW 634
Query: 9472 KCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSD 9651
+CDG DDC D SDE++C +N+ + Q C+ QF C +G CI K+C+ DC D SD
Sbjct: 635 RCDGEDDCSDNSDEENC-ENTGTPQ----CAPDQFLCGNGRCIGQRKLCNGANDCGDGSD 689
Query: 9652 ESS------LCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNECY 9813
ES + C++ C QKC ++ +C C G+ + + D +SC +VNEC
Sbjct: 690 ESPHQNCRPRTGEENCNVNNGG-CAQKCQMVRGMVQCTCHTGYRL-LEDGRSCQDVNECA 747
Query: 9814 EGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDG 9993
E CSQ C + G ++C C GY+L D SCK + PEP L AN+ IR++
Sbjct: 748 EE-GYCSQGCTNSEGGFQCWCEQGYELRPDKRSCKA--LGPEPVLLFANRIDIRQVLPHR 804
Query: 9994 NKYELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNVYG 10173
++Y L +N ++LD +++ + D R++R +L+ S+ E V+ +
Sbjct: 805 SEYTLLLNNLENAIALDFHHSKELVFWSDVTLDRIMRANLNG-----SNVEEVVSTGLES 859
Query: 10174 TEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFFTE 10353
G+A+DW+ KLY + I V LDG K L+ +++P+AI +HP +G +++T+
Sbjct: 860 PGGLAIDWIHDKLYWTDSGTSRIEVANLDGTHRKVLLWQNLEKPRAIALHPMEGTIYWTD 919
Query: 10354 WSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDF 10533
W P I +DGS +A+ L WPN + IDY R++W DA + I D
Sbjct: 920 WGNTPRIEYSNMDGSNRRI-----IADTHLFWPNGLTIDYAGHRMYWVDAKHHVIERADL 974
Query: 10534 DGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDL 10713
DG R+ + +Q H ++ VF+D LYW DW+ + + +K+TGKN+ I++ + P D+
Sbjct: 975 DGRNRKAVISQGLPHPFAITVFEDSLYWTDWHTKSINSANKFTGKNQEIIRNKLHFPMDI 1034
Query: 10714 RIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTCEPNCTE 10887
+HP RQPA N CG NNGGC+HLCL YTC+CP F +KT C +
Sbjct: 1035 HTLHPQRQPAGRNRCGANNGGCTHLCL--PSSKDYTCACPTGF-----RKTSSHACAQ 1085
Score = 320 bits (821), Expect = 5e-85
Identities = 236/798 (29%), Positives = 344/798 (42%), Gaps = 88/798 (11%)
Frame = +1
Query: 11416 CIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSD 11595
CIP C+G +DC D+SDED PTC + +F C +GKCI R W+CD +NDC D+SD
Sbjct: 341 CIPAQWQCDGDNDCGDHSDEDGCMLPTCSPL-DFHC-DNGKCIRRSWVCDGDNDCEDDSD 398
Query: 11596 ELD----------------------------------ASC------------GGTTRPCS 11637
E D A+C R C
Sbjct: 399 EQDCPSSPFKPSSLRREKGAVRMLPAQTAIALKAGLSAACKVLSSEELPWKAASPPRECE 458
Query: 11638 ESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQCDDGTCIAEHKWCDRK 11817
E EF C +G CI CDG C D DE QC +R+C +C DG+CIAEH +CD
Sbjct: 459 EDEFSCQNGYCIRSLWHCDGDNDCGDNSDE-QCDMRKCSEKEFRCSDGSCIAEHWFCDGD 517
Query: 11818 KDCPNAADELHC-EDVSRRTCSPFEFECANSVCIPRKFMXXXXXXXXXXSDETSSECRSA 11994
DC + +DE +C DV TCS EF+CA CI + SDE S+C S
Sbjct: 518 TDCKDGSDEENCPSDVPAATCSLEEFQCAYGRCILDIYHCDGDDDCGDWSDE--SDCSSH 575
Query: 11995 QCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEH---LSMCSS------------- 12126
Q F C +S LC+N C+G +DC +D SDE SMC++
Sbjct: 576 QPCRSGEFMC-NSGLCINAGWRCDGDSDC--DDQSDERNCTTSMCTADQFRCKSGRCVRL 632
Query: 12127 ---------FSEYGD-----------CSSDQFKCANGKCVNGTVACDRKDDCGDASDEI- 12243
S+ D C+ DQF C NG+C+ C+ +DCGD SDE
Sbjct: 633 SWRCDGEDDCSDNSDEENCENTGTPQCAPDQFLCGNGRCIGQRKLCNGANDCGDGSDESP 692
Query: 12244 --GCSKHGGKTSCEAFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGN 12417
C G+ +C NNGGC C VR C C G+R + + C D++ECA
Sbjct: 693 HQNCRPRTGEENCNV--NNGGCAQKCQMVRGMVQCTCHTGYRL-LEDGRSCQDVNECAEE 749
Query: 12418 NTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHG 12597
C+Q C N++G + C C + YE + C+A G ++ + Q+ H
Sbjct: 750 GYCSQGCTNSEGGFQCWCEQGYELR-----PDKRSCKALGPEPVLLFANRIDIRQVLPH- 803
Query: 12598 SGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVD 12777
R KEL++W S+ T+ R AN N S+ + +
Sbjct: 804 ----RSEYTLLLNNLENAIALDFHHSKELVFW---SDVTLDRIMRANLNGSNVEEVVSTG 856
Query: 12778 FAAMGVVPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDG 12957
+ P +A+D+ L+ + T I V DG
Sbjct: 857 LES----PGGLAIDWIHDKLYWT-----------------------DSGTSRIEVANLDG 889
Query: 12958 RYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTS 13137
+ K ++ +L++P A+ P G I ++D G +IE ++MDG++R+II +F P
Sbjct: 890 THRKVLLWQNLEKPRAIALHPMEGTIYWTDWGNTPRIEYSNMDGSNRRIIADTHLFWPNG 949
Query: 13138 MAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVV-HDRHIPYAVDVFENHIYWLSRESK 13314
+ ID G+R+YWVD K+ ++ ++DG R V+ P+A+ VFE+ +YW +K
Sbjct: 950 LTIDYA-GHRMYWVDAKHHVIERADLDGRNRKAVISQGLPHPFAITVFEDSLYWTDWHTK 1008
Query: 13315 TLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPST-G 13491
++ +KF ++ + L + + R G C+HLC LPS+
Sbjct: 1009 SINSANKFTGKNQEIIRNKLHFPMDIHTLHPQRQPAGRNRCGANNGGCTHLC--LPSSKD 1066
Query: 13492 FACLCPDGIVPQLDGSCA 13545
+ C CP G +CA
Sbjct: 1067 YTCACPTGFRKTSSHACA 1084
Score = 232 bits (591), Expect = 2e-58
Identities = 191/718 (26%), Positives = 315/718 (43%), Gaps = 11/718 (1%)
Frame = +1
Query: 1018 NEC-AEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLF 1194
N C A G C LC +TC+C P T C + + DK LF
Sbjct: 1047 NRCGANNGGCTHLCLPSSKDYTCAC------------PTGFRKTSSHAC-AQSLDKFLLF 1093
Query: 1195 VARREGLYRLNPKNPD--EEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDE 1368
ARR + R++ D ++V LA +D+D D ++WTD S A D
Sbjct: 1094 -ARRMDIRRISFDTDDLSDDVIPLADVRSAVALDWDSKDDYVYWTDVSTDSISRAKWDGS 1152
Query: 1369 GEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLP 1548
G+ + SL+S P LA+DW+TN LY ++G+ RI+VS+ DG RTVL+ + L P
Sbjct: 1153 GQ-EVVVDTSLES---PAGLAIDWVTNKLYWTDAGTDRIEVSNTDGTMRTVLIWENLDRP 1208
Query: 1549 LDIALDPLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVD 1719
DI +DP+ G M++T+ K+E A MD +NR +++++ +G+ +D ++R+YW D
Sbjct: 1209 RDIVVDPVGGFMYWTDWGANPKIERAGMDASNRLVIISSNLTWPNGLAIDYESQRLYWAD 1268
Query: 1720 PKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVE-KFGSDT 1896
+ +E G++R+++ G N +PHPFGL L+ + +YWTDW + + + G
Sbjct: 1269 AGMKTIEYASLDGSNRKVLI-GSN-LPHPFGLTLYGERIYWTDWQAKSIQSADRRTGQAR 1326
Query: 1897 KLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPC--TNADCEGMCILSKDNGG 2070
+ L N EN M I +H P + PC N C +C+L+
Sbjct: 1327 ETLQDNLEN---LMDIHVFHRHRPP-----------VRTPCEVNNGGCSHLCLLAP---- 1368
Query: 2071 FGVGYKCACPIGQKL-VNGKRCIDSIDYLLFSSNKIVRGIFPEINEKALAEAVLPISPIS 2247
GY C CP G L +GK C + V+ ++
Sbjct: 1369 LPKGYSCTCPTGINLQSDGKTC--------------------------STDVVVSVNVTM 1402
Query: 2248 QRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWISK 2427
+ I + D H +++D I R DG ++ T ++ D I +
Sbjct: 1403 KNTIA----IGVDPHEGKVYWSDSTLRKISRAALDGSKFEDIITTGLLTTDGLAVDAIGR 1458
Query: 2428 QLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITE-LRDPVSVVVHPWKGLLFYAEAMR 2604
++Y+ D N +EV + D +R+ L+ + L P ++ ++ G +++ +
Sbjct: 1459 KIYWTDTGTNRIEVGNL--------DGSMRKVLVWQNLDSPRAIALYHEMGYMYWTDWGE 1510
Query: 2605 PAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVKL 2784
A + R +DG V+ + LG P+ +A+D A ++L W D + I D +G N L
Sbjct: 1511 NAKLERSGMDGSGRVVLISNNLGWPNGLAVDKAGSQLLWADAHTERIEAADLNGANRRTL 1570
Query: 2785 DIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQ 2964
P +T+++ YIY+ + SI R K +G +VR A+ + ++A
Sbjct: 1571 LSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKDSGANVILVR---ANLPGLMDIQAVDRA 1627
Query: 2965 NQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINKENNHSCQKDP 3138
P + R C+ LC P+ CAC G + K + +C P
Sbjct: 1628 R---PLGFNKCGVRNGGCSHLCL-------PHPTGFSCACPTGIQL-KRDEQTCDSSP 1674
Score = 225 bits (574), Expect = 2e-56
Identities = 126/349 (36%), Positives = 188/349 (53%), Gaps = 3/349 (0%)
Frame = +1
Query: 9802 NECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKI 9981
N+C GCS C + C C G QL D+ +C + PE + L +++ IR+I
Sbjct: 1633 NKCGVRNGGCSHLCLPHPTGFSCACPTGIQLKRDEQTC---DSSPETYLLFSSRASIRRI 1689
Query: 9982 SIDGNKY---ELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETV 10152
S+D + + + +NV+SLD D + K Y D + R DL+ S+ ETV
Sbjct: 1690 SLDTSDHTDVHIPVPELNNVISLDYDSVDGKIYYTDVFLDVIRRSDLNG-----SNMETV 1744
Query: 10153 LRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGK 10332
+ + T+G+AVDWV R LY + ++ V LDG K LI + + +P+AI V P K
Sbjct: 1745 IGQGLKTTDGLAVDWVARNLYWTDTGRNTVEVARLDGSSRKVLINNSLDEPRAIAVFPKK 1804
Query: 10333 GYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLN 10512
GYLF+T+W I R LDGS L DLGWPN + +DY + R++W DAHL+
Sbjct: 1805 GYLFWTDWGHIAKIERANLDGSERK-----ILINTDLGWPNGLTLDYDTRRIYWVDAHLD 1859
Query: 10513 EIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKT 10692
I D +G R+ + +Q SH ++ D ++YW DW + + R DK++G+N+ +
Sbjct: 1860 RIESCDLNGKLRQVLVSQ-VSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVLAN 1918
Query: 10693 VQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQ 10839
V+ D+ +V P RQ N CG NNGGC+HLC A + + C+CPD+
Sbjct: 1919 VEGLMDIIVVSPQRQTG-TNACGVNNGGCTHLCF--ARASDFVCACPDE 1964
Score = 219 bits (557), Expect = 2e-54
Identities = 175/658 (26%), Positives = 297/658 (44%), Gaps = 14/658 (2%)
Frame = +1
Query: 1285 IDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYII 1464
I D + K++W+D A +D S+ + + L+ LAVD I +Y
Sbjct: 1408 IGVDPHEGKVYWSDSTLRKISRAALDG----SKFEDIITTGLLTTDGLAVDAIGRKIYWT 1463
Query: 1465 ESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFTN---QLKLEAAAMDGTN 1635
++G+ RI+V + DG R VL+ L P IAL G M++T+ KLE + MDG+
Sbjct: 1464 DTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIALYHEMGYMYWTDWGENAKLERSGMDGSG 1523
Query: 1636 RRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGL 1815
R L++ + +G+ VD ++ W D +R+E+ D G +RR + ++ V HP+GL
Sbjct: 1524 RVVLISNNLGWPNGLAVDKAGSQLLWADAHTERIEAADLNGANRRTL---LSPVQHPYGL 1580
Query: 1816 ALFDQYLYWTDWTRLGVIQVEK-FGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSEC 1992
L D Y+YWTDW + + +K G++ L+ +N + + P+ G ++C
Sbjct: 1581 TLLDSYIYWTDWQTRSIHRADKDSGANVILVRANLPGLMDIQAVDRARPL-----GFNKC 1635
Query: 1993 LAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGKRCIDSID--YLLFSS 2166
N C +C+ G+ CACP G +L ++ DS YLLFSS
Sbjct: 1636 -------GVRNGGCSHLCLPHP------TGFSCACPTGIQLKRDEQTCDSSPETYLLFSS 1682
Query: 2167 NKIVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIR 2346
+R I + ++ +P + ++ D +Y D+ + I R
Sbjct: 1683 RASIRRISLDTSDHTDVHIPVP-------ELNNVISLDYDSVDGKIYYTDVFLDVIRRSD 1735
Query: 2347 PDGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQL 2526
+G V+ ++ DW+++ LY+ D RN++EV ++ D R+ L
Sbjct: 1736 LNGSNMETVIGQGLKTTDGLAVDWVARNLYWTDTGRNTVEVARL--------DGSSRKVL 1787
Query: 2527 ITE-LRDPVSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFA 2703
I L +P ++ V P KG LF+ + A I R ++DG +++ NT LG P+ + +D+
Sbjct: 1788 INNSLDEPRAIAVFPKKGYLFWTDWGHIAKIERANLDGSERKILINTDLGWPNGLTLDYD 1847
Query: 2704 ENRLCWGDTLLKTISCMDFDGKNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKK 2883
R+ W D L I D +GK L P A+T + +IY+ + SI+RV K
Sbjct: 1848 TRRIYWVDAHLDRIESCDLNGKLRQVLVSQVSHPFALTQQDRWIYWTDWQTKSIQRVDKY 1907
Query: 2884 NGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQ--CTQLCFATPSE--- 3048
+G + V A+ + + S Q Q + + C + CT LCFA S+
Sbjct: 1908 SGRNKETVL---ANVEGLMDIIVVSPQRQ-----TGTNACGVNNGGCTHLCFARASDFVC 1959
Query: 3049 SHPNELEAK-CACRQGFM-INKENNHSCQKDPAEKIEQLCSSNSTQFQCKNGRCIPKE 3216
+ P+E + + C+ G + E + P +I + T + + G C K+
Sbjct: 1960 ACPDEPDGRPCSTVPGVVPFGPEITSERSQTPPGRIGTSTTKPLTSLEEEEGNCSDKD 2017
Score = 200 bits (508), Expect = 1e-48
Identities = 181/747 (24%), Positives = 314/747 (41%), Gaps = 49/747 (6%)
Frame = +1
Query: 6250 CHINNGNCDHICIPLMFAQRTCTCANGY--VKDGQTSCK----LFDESFVIVATKTKVIG 6411
C++NNG C C ++ CTC GY ++DG+ SC+ +E + G
Sbjct: 705 CNVNNGGCAQKC-QMVRGMVQCTCHTGYRLLEDGR-SCQDVNECAEEGYCSQGCTNSEGG 762
Query: 6412 YPI----------DETQSKGVAMEPI----GGLSITGV--------------------DY 6489
+ D+ K + EP+ + I V D+
Sbjct: 763 FQCWCEQGYELRPDKRSCKALGPEPVLLFANRIDIRQVLPHRSEYTLLLNNLENAIALDF 822
Query: 6490 DYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINYNMYFINHD 6669
+ + ++ ++ + +++ + A G + V S G + LAIDWI+ +Y+ D
Sbjct: 823 HHSKELVFWSDVT-LDRIMRANLNGSNVEEVV---STGLESPGGLAIDWIHDKLYWT--D 876
Query: 6670 AERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQRSFLDGSRR 6849
+ + IEV+ LDGT+RK+LL E P +IA+ P+ +YW D G P I+ S +DGS R
Sbjct: 877 SGTSRIEVANLDGTHRKVLLWQNLEKPRAIALHPMEGTIYWTDWGNTPRIEYSNMDGSNR 936
Query: 6850 EVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPELVRSD-IASAAGVALH 7026
+I + + P L +D A +YW DAK I R G + V S + + +
Sbjct: 937 RIIADTHLFWPNGLTIDYAGHRMYWVDAKHHVIERADLDGRNRKAVISQGLPHPFAITVF 996
Query: 7027 GQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRASSPCQI 7206
++YWTD + + A + + + L D+ QP + C
Sbjct: 997 EDSLYWTDWHTKSINSANKFTGKNQEI-----IRNKLHFPMDIHTLHPQRQPAGRNRC-- 1049
Query: 7207 TDNLRKSPCTQLCFATPGTQTPTCSCARGVLK--GRTCEEP-DTYIMFSDGDKIIDVAIE 7377
CT LC P ++ TC+C G K C + D +++F+ I ++ +
Sbjct: 1050 --GANNGGCTHLCL--PSSKDYTCACPTGFRKTSSHACAQSLDKFLLFARRMDIRRISFD 1105
Query: 7378 PDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAENPRLVFGA 7557
D + + P ++ + D D VY+ S ++ + + + E +V
Sbjct: 1106 TDDLSDDVI--PLADVRSAVALDWDSKDDYVYWTDVSTDSISRAKWDGSGQE---VVVDT 1160
Query: 7558 SKQPHAKEIRHISDMKLDWLTQKIYFTTGRGGKVMAIDTAGEHLSTIA--SGDWTYALAI 7731
S + A + +DW+T K+Y+T ++ +T G + + + D + +
Sbjct: 1161 SLESPA-------GLAIDWVTNKLYWTDAGTDRIEVSNTDGTMRTVLIWENLDRPRDIVV 1213
Query: 7732 DPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVDFRNQKIYW 7911
DP G ++W+D G P+IER+ + +R VI+S +++ P +A+D+ +Q++YW
Sbjct: 1214 DPVGGFMYWTDWGAN-------PKIERAGMDASNRLVIISSNLTWPNGLAIDYESQRLYW 1266
Query: 7912 ADVNRLNIEVADYDGQNRKVIASGY--RAKSLDIWDRWLYMSDPLSNGVFRIDKESGSGL 8085
AD IE A DG NRKV+ L ++ +Y +D + + D+ +G
Sbjct: 1267 ADAGMKTIEYASLDGSNRKVLIGSNLPHPFGLTLYGERIYWTDWQAKSIQSADRRTGQAR 1326
Query: 8086 ENVVSDRRIPGALRVF-ASESDVRTRNQVCNALTSQLCKTDNGGCDQLCTVVADDIGLAA 8262
E + + + VF VRT C+ +NGGC LC + G +
Sbjct: 1327 ETLQDNLENLMDIHVFHRHRPPVRTP-----------CEVNNGGCSHLCLLAPLPKGYS- 1374
Query: 8263 SKVQCSCNDTYELVQEPGKDYPTQCVL 8343
C+C L Q GK T V+
Sbjct: 1375 ----CTCPTGINL-QSDGKTCSTDVVV 1396
Score = 197 bits (501), Expect = 6e-48
Identities = 113/359 (31%), Positives = 171/359 (47%), Gaps = 3/359 (0%)
Frame = +1
Query: 9802 NECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKI 9981
N C GC+ C Y C C G++ +S H+C ++ + F L A + IR+I
Sbjct: 1047 NRCGANNGGCTHLCLPSSKDYTCACPTGFRKTSS-HACAQSL---DKFLLFARRMDIRRI 1102
Query: 9982 SIDGNKYE---LAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETV 10152
S D + + + V+LD D + Y D + R D S E V
Sbjct: 1103 SFDTDDLSDDVIPLADVRSAVALDWDSKDDYVYWTDVSTDSISRAKWDG-----SGQEVV 1157
Query: 10153 LRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGK 10332
+ ++ G+A+DWV KLY + I V DG LI + + +P+ IVV P
Sbjct: 1158 VDTSLESPAGLAIDWVTNKLYWTDAGTDRIEVSNTDGTMRTVLIWENLDRPRDIVVDPVG 1217
Query: 10333 GYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLN 10512
G++++T+W P I R +D S L + +L WPN +AIDY S RL+W DA +
Sbjct: 1218 GFMYWTDWGANPKIERAGMDASNRLV-----IISSNLTWPNGLAIDYESQRLYWADAGMK 1272
Query: 10513 EIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKT 10692
I + DG+ R+ + H + ++ + +YW DW + + D+ TG+ L+
Sbjct: 1273 TIEYASLDGSNRKVLIGSNLPHPFGLTLYGERIYWTDWQAKSIQSADRRTGQARETLQDN 1332
Query: 10693 VQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTC 10869
++ D+ + H R P PC NNGGCSHLCL+ GY+C+CP L SD KTC
Sbjct: 1333 LENLMDIHVFHRHRPPV-RTPCEVNNGGCSHLCLLAPLPKGYSCTCPTGINLQSDGKTC 1390
Score = 176 bits (445), Expect = 2e-41
Identities = 107/357 (29%), Positives = 163/357 (44%), Gaps = 2/357 (0%)
Frame = +1
Query: 9808 CYEGISGCSQKC--DDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKI 9981
C GCS C Y C C G L SD +C + +
Sbjct: 1353 CEVNNGGCSHLCLLAPLPKGYSCTCPTGINLQSDGKTCSTDVV----------------V 1396
Query: 9982 SIDGNKYELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRH 10161
S++ N +++ +D E K Y D ++ R LD S +E ++
Sbjct: 1397 SVNVT--------MKNTIAIGVDPHEGKVYWSDSTLRKISRAALDG-----SKFEDIITT 1443
Query: 10162 NVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYL 10341
+ T+G+AVD +GRK+Y + I V LDG K L+ + P+AI ++ GY+
Sbjct: 1444 GLLTTDGLAVDAIGRKIYWTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIALYHEMGYM 1503
Query: 10342 FFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIG 10521
++T+W + R +DGS + L ++LGWPN +A+D +L W DAH I
Sbjct: 1504 YWTDWGENAKLERSGMDGSGRV-----VLISNNLGWPNGLAVDKAGSQLLWADAHTERIE 1558
Query: 10522 FMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQL 10701
D +G RR + H + + D Y+YW DW R + R DK +G N +++ +
Sbjct: 1559 AADLNGANRRTL-LSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKDSGANVILVRANLPG 1617
Query: 10702 PNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTCE 10872
D++ V R P N CG NGGCSHLCL G++C+CP L D++TC+
Sbjct: 1618 LMDIQAVDRAR-PLGFNKCGVRNGGCSHLCL--PHPTGFSCACPTGIQLKRDEQTCD 1671
Score = 156 bits (395), Expect = 1e-35
Identities = 102/303 (33%), Positives = 131/303 (42%), Gaps = 12/303 (3%)
Frame = +1
Query: 8335 CVLRGSNSEPAKECLPPYN-----FQCGDGSCILLGATCDSKPDCADASDENPNYCNTRS 8499
C + S P K PP F C +G CI CD DC D SDE C+ R
Sbjct: 438 CKVLSSEELPWKAASPPRECEEDEFSCQNGYCIRSLWHCDGDNDCGDNSDEQ---CDMRK 494
Query: 8500 CPEDYNLCTNRRCIDSAKKCNHIDDCGDGSDELDCPS---AVACAEGTFPCSNGHCINQT 8670
C E C++ CI C+ DC DGSDE +CPS A C+ F C+ G CI
Sbjct: 495 CSEKEFRCSDGSCIAEHWFCDGDTDCKDGSDEENCPSDVPAATCSLEEFQCAYGRCILDI 554
Query: 8671 KVCDGHNDCHDEQVSDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKAD 8850
CDG +DC D SDES + CR + C N+ +CI CDG DC D++D
Sbjct: 555 YHCDGDDDCGD--WSDESDCSSHQ---PCRSGEFMC-NSGLCINAGWRCDGDSDCDDQSD 608
Query: 8851 ENQLFCMNQQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDY 9030
E C C RC SGRC+ +W+CDG++DCSD DE NC +T G C D
Sbjct: 609 ERN--CTTSMCTADQFRCKSGRCVRLSWRCDGEDDCSDNSDE--ENCENT-GTPQCAPDQ 663
Query: 9031 LFQCDNLKCISRAFIXXXXXXXXXXXXXHSRHGC----GNRTCTDQEFHCTSNAKLAQPK 9198
F C N +CI + + C G C C ++ +
Sbjct: 664 -FLCGNGRCIGQRKLCNGANDCGDGSDESPHQNCRPRTGEENCNVNNGGCAQKCQMVRGM 722
Query: 9199 YEC 9207
+C
Sbjct: 723 VQC 725
Score = 144 bits (363), Expect = 6e-32
Identities = 104/370 (28%), Positives = 176/370 (47%), Gaps = 9/370 (2%)
Frame = +1
Query: 1018 NECA-EFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLF 1194
N+C G C LC H GF+C+C +Q++ +D T +++ + L
Sbjct: 1633 NKCGVRNGGCSHLCLPHPTGFSCACPTG---IQLK----RDEQTC------DSSPETYLL 1679
Query: 1195 VARREGLYRLNPKNPDEEVKKLASGEF--IYGIDFDYGDRKIFWTDRLAHSAFSADVDDE 1368
+ R + R++ D + E + +D+D D KI++TD +D++
Sbjct: 1680 FSSRASIRRISLDTSDHTDVHIPVPELNNVISLDYDSVDGKIYYTDVFLDVIRRSDLNG- 1738
Query: 1369 GEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLP 1548
S ++ + + L LAVDW+ LY ++G ++V+ DG R VL+ + L P
Sbjct: 1739 ---SNMETVIGQGLKTTDGLAVDWVARNLYWTDTGRNTVEVARLDGSSRKVLINNSLDEP 1795
Query: 1549 LDIALDPLRGEMFFTNQ---LKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVD 1719
IA+ P +G +F+T+ K+E A +DG+ R+ L+NT +G+ +D +R+YWVD
Sbjct: 1796 RAIAVFPKKGYLFWTDWGHIAKIERANLDGSERKILINTDLGWPNGLTLDYDTRRIYWVD 1855
Query: 1720 PKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKF-GSDT 1896
+DR+ES D G R+++ ++ V HPF L D+++YWTDW + +V+K+ G +
Sbjct: 1856 AHLDRIESCDLNGKLRQVL---VSQVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNK 1912
Query: 1897 KLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPC--TNADCEGMCILSKDNGG 2070
+ + +N E M I P Q G N C N C +C +
Sbjct: 1913 ETVLANVEG---LMDIIVVSPQRQTG-----------TNACGVNNGGCTHLCFARASD-- 1956
Query: 2071 FGVGYKCACP 2100
+ CACP
Sbjct: 1957 ----FVCACP 1962
Score = 139 bits (350), Expect = 2e-30
Identities = 116/351 (33%), Positives = 144/351 (40%), Gaps = 26/351 (7%)
Frame = +1
Query: 11515 FRCATSG----KCIPRRWMCDTENDCGDNSDELDASCGGTTRP-CSESEFRCNDGKCIPG 11679
F CA S CIP +W CD +NDCGD+SDE G P CS +F C++GKCI
Sbjct: 329 FTCAVSAFGECTCIPAQWQCDGDNDCGDHSDE-----DGCMLPTCSPLDFHCDNGKCIRR 383
Query: 11680 SKVCDGTIQCSDGLDESQC--------TLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNA 11835
S VCDG C D DE C +LRR R T IA K A
Sbjct: 384 SWVCDGDNDCEDDSDEQDCPSSPFKPSSLRREKGAVRMLPAQTAIA------LKAGLSAA 437
Query: 11836 ADELHCEDVSRRTCSP------FEFECANSVCIPRKFMXXXXXXXXXXSDETSSECRSAQ 11997
L E++ + SP EF C N CI + SDE +C +
Sbjct: 438 CKVLSSEELPWKAASPPRECEEDEFSCQNGYCIRSLWHCDGDNDCGDNSDE---QCDMRK 494
Query: 11998 CDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSFSEYGDCSSDQFKCANG 12177
C FRC+ C+ C+G DC D SDE C S CS ++F+CA G
Sbjct: 495 CSEK-EFRCSDGS-CIAEHWFCDGDTDC--KDGSDEE--NCPSDVPAATCSLEEFQCAYG 548
Query: 12178 KCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKHICTDVRDGFYCHCRDG 12357
+C+ CD DDCGD SDE CS H S E N+G C + G+ C DG
Sbjct: 549 RCILDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMCNSGLC------INAGWRC---DG 599
Query: 12358 FRP-DPQSPKECIDIDECAG------NNTCTQLCLNTKGSYLCRCHEDYEN 12489
D QS + C + C +L G C + D EN
Sbjct: 600 DSDCDDQSDERNCTTSMCTADQFRCKSGRCVRLSWRCDGEDDCSDNSDEEN 650
Score = 122 bits (306), Expect = 3e-25
Identities = 94/317 (29%), Positives = 130/317 (40%), Gaps = 27/317 (8%)
Frame = +1
Query: 3556 TCAANQFSCANGR-----CIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQ 3720
+C N F+CA CIP W CDGDNDC D +DED C CS L F C NG+
Sbjct: 323 SCGRNHFTCAVSAFGECTCIPAQWQCDGDNDCGDHSDED--GCMLPTCSPLDFHCDNGK- 379
Query: 3721 CVPLRNHXXXXXXXXXXXXXXXXAVTAESCTPDQFKCVSSGL-CIPA----SWKXXXXXX 3885
C+ R + P + + +PA + K
Sbjct: 380 CI--RRSWVCDGDNDCEDDSDEQDCPSSPFKPSSLRREKGAVRMLPAQTAIALKAGLSAA 437
Query: 3886 XXXXSDE--PKFGCTSGRQCSSDQFKCGNGRCILNNWLCDGENDCGDGSDESSERGCKTS 4059
S E P + R+C D+F C NG CI + W CDG+NDCGD SDE +
Sbjct: 438 CKVLSSEELPWKAASPPRECEEDEFSCQNGYCIRSLWHCDGDNDCGDNSDEQCD------ 491
Query: 4060 MNARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCSFKCH 4239
RKC + C + +CI H CDG T C G+DE C D+ +A CS +
Sbjct: 492 --MRKCSEKEFRCSDG--SCIAEHWFCDGDTDCKDGSDE-ENCPSDVPAAT---CSLE-- 541
Query: 4240 NSPNGPICSCPFGEQLVNKTKCEPENEC---LDSSSCS--QRCKDEKH----------GF 4374
C +G +++ C+ +++C D S CS Q C+ + G+
Sbjct: 542 ------EFQCAYGRCILDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMCNSGLCINAGW 595
Query: 4375 TCSCDEGYELDVDKRTC 4425
C D + D+R C
Sbjct: 596 RCDGDSDCDDQSDERNC 612
Score = 104 bits (260), Expect = 6e-20
Identities = 91/398 (22%), Positives = 162/398 (39%), Gaps = 10/398 (2%)
Frame = +1
Query: 12409 AGNNTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKD----CRAKGDAANVMIGADD-- 12570
A N CT LCL + Y C C + D + D + DD
Sbjct: 1051 ANNGGCTHLCLPSSKDYTCACPTGFRKTSSHACAQSLDKFLLFARRMDIRRISFDTDDLS 1110
Query: 12571 -SLVQLSLHGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERTIYRSAIANGNQ 12747
++ L+ + + +YW D S +I R+
Sbjct: 1111 DDVIPLA----------------DVRSAVALDWDSKDDYVYWTDVSTDSISRA-----KW 1149
Query: 12748 SHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNT 12927
GQ++ VD + P +A+D+ T L+ ++ I+ NT
Sbjct: 1150 DGSGQEVVVDTSLES--PAGLAIDWVTNKLYWTDAG---------------TDRIEVSNT 1192
Query: 12928 GFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQII 13107
DG ++ +L +P ++ P G + ++D G + KIE A MD ++R +I
Sbjct: 1193 --------DGTMRTVLIWENLDRPRDIVVDPVGGFMYWTDWGANPKIERAGMDASNRLVI 1244
Query: 13108 VKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVV-HDRHIPYAVDVFEN 13284
+ + P +AID + R+YW D + ++ ++DGS R ++ + P+ + ++
Sbjct: 1245 ISSNLTWPNGLAIDY-ESQRLYWADAGMKTIEYASLDGSNRKVLIGSNLPHPFGLTLYGE 1303
Query: 13285 HIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSH 13464
IYW ++K++ D+ L +LE+ + V ++ + RT CSH
Sbjct: 1304 RIYWTDWQAKSIQSADRRTGQARETLQDNLENLMDIHVFHRH-RPPVRTPCEVNNGGCSH 1362
Query: 13465 LCVSLP-STGFACLCPDGIVPQLDG-SCATQHVEALTM 13572
LC+ P G++C CP GI Q DG +C+T V ++ +
Sbjct: 1363 LCLLAPLPKGYSCTCPTGINLQSDGKTCSTDVVVSVNV 1400
Score = 103 bits (258), Expect = 9e-20
Identities = 73/283 (25%), Positives = 135/283 (46%)
Frame = +1
Query: 12670 PRKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAA 12849
P + +YW D + R I R+A+ +G K + D G++ TT L + A
Sbjct: 1412 PHEGKVYWSDSTLRKISRAAL-------DGSKFE-DIITTGLL--------TTDGLAVDA 1455
Query: 12850 VSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAG 13029
+ I + T I V DG K +V +L P A+ G
Sbjct: 1456 IGRKIY--------------WTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIALYHEMG 1501
Query: 13030 RICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAV 13209
+ ++D G +AK+E + MDG+ R +++ + + P +A+D+ G+++ W D R++A
Sbjct: 1502 YMYWTDWGENAKLERSGMDGSGRVVLISNNLGWPNGLAVDKA-GSQLLWADAHTERIEAA 1560
Query: 13210 NIDGSERTTVVHDRHIPYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHT 13389
+++G+ R T++ PY + + +++IYW ++++++ DK V ++ ++L
Sbjct: 1561 DLNGANRRTLLSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKDSGANVILVRANLPGLMD 1620
Query: 13390 VRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTGFACLCPDGI 13518
++ + A+ G CSHLC+ P TGF+C CP GI
Sbjct: 1621 IQAVDR-ARPLGFNKCGVRNGGCSHLCLPHP-TGFSCACPTGI 1661
Score = 94.0 bits (232), Expect = 1e-16
Identities = 57/188 (30%), Positives = 96/188 (50%), Gaps = 1/188 (0%)
Frame = +1
Query: 12952 DGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSP 13131
DG K ++ L +P A+ P G + ++D G AKIE A++DG+ R+I++ + P
Sbjct: 1780 DGSSRKVLINNSLDEPRAIAVFPKKGYLFWTDWGHIAKIERANLDGSERKILINTDLGWP 1839
Query: 13132 TSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSRES 13311
+ +D RIYWVD R+++ +++G R +V P+A+ + IYW ++
Sbjct: 1840 NGLTLDYDT-RRIYWVDAHLDRIESCDLNGKLRQVLVSQVSHPFALTQQDRWIYWTDWQT 1898
Query: 13312 KTLYVQDKF-GRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPST 13488
K++ DK+ GR + +VLA+ +G + + T G C+HLC + S
Sbjct: 1899 KSIQRVDKYSGRNKETVLAN--VEGLMDIIVVSPQRQTGTNACGVNNGGCTHLCFARAS- 1955
Query: 13489 GFACLCPD 13512
F C CPD
Sbjct: 1956 DFVCACPD 1963
Score = 89.7 bits (221), Expect = 2e-15
Identities = 74/268 (27%), Positives = 97/268 (35%), Gaps = 56/268 (20%)
Frame = +1
Query: 505 SDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEF 684
S + SC RNH C F + CI W CDG DC D SDE D C C+ +F
Sbjct: 318 SSTECSCGRNHFTCAVSAF---GECTCIPAQWQCDGDNDCGDHSDE-DGCMLPTCSPLDF 373
Query: 685 QCKNKRCQPRKFRCDYYDDCGDNSDEDEC--------------GEYR------------- 783
C N +C R + CD +DC D+SDE +C G R
Sbjct: 374 HCDNGKCIRRSWVCDGDNDCEDDSDEQDCPSSPFKPSSLRREKGAVRMLPAQTAIALKAG 433
Query: 784 -----------------------CPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCS 894
C +++C G+CI L CDG DC D +DE QC
Sbjct: 434 LSAACKVLSSEELPWKAASPPRECEEDEFSCQ-NGYCIRSLWHCDGDNDCGDNSDE-QCD 491
Query: 895 QNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPG 1074
C E C G + + H C +C + G ++ C + P
Sbjct: 492 MRKCSE-------------KEFRCSDGSCIAE--HWFCDGDTDCKD-GSDEENCPSDVPA 535
Query: 1075 FTCS------CLGDCFTLQMEHGPGKDN 1140
TCS G C L + H G D+
Sbjct: 536 ATCSLEEFQCAYGRCI-LDIYHCDGDDD 562
Score = 65.5 bits (158), Expect = 4e-08
Identities = 51/205 (24%), Positives = 76/205 (36%), Gaps = 21/205 (10%)
Frame = +1
Query: 139 NTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHS 318
N +S+C + FRC G+C+R W
Sbjct: 611 NCTTSMCTADQFRCKSGRCVRLSW------------------------------------ 634
Query: 319 VSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCR 498
RCD DC+D SDE++C + + + F+C +GR C K C+G DC
Sbjct: 635 --------RCDGEDDCSDNSDEENCENTGTPQCAPDQFLCGNGR-CIGQRKLCNGANDCG 685
Query: 499 DLSDE-----------KDSCSRNHTACFQ--------YQFRCADKTQCIQKSWVCDGSKD 621
D SDE +++C+ N+ C Q Q C + ++ C +
Sbjct: 686 DGSDESPHQNCRPRTGEENCNVNNGGCAQKCQMVRGMVQCTCHTGYRLLEDGRSCQDVNE 745
Query: 622 CADGSDEPDTCEFKKCTANE--FQC 690
CA E C + CT +E FQC
Sbjct: 746 CA----EEGYCS-QGCTNSEGGFQC 765
Score = 58.2 bits (139), Expect = 6e-06
Identities = 37/96 (38%), Positives = 44/96 (45%), Gaps = 7/96 (7%)
Frame = +1
Query: 3910 KFGCTSGRQCSS--DQFKC-----GNGRCILNNWLCDGENDCGDGSDESSERGCKTSMNA 4068
KFG TS +CS + F C G CI W CDG+NDCGD SDE GC
Sbjct: 313 KFGITSSTECSCGRNHFTCAVSAFGECTCIPAQWQCDGDNDCGDHSDED---GCMLP--- 366
Query: 4069 RKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDE 4176
C C+N + CI +CDG C +DE
Sbjct: 367 -TCSPLDFHCDNGK--CIRRSWVCDGDNDCEDDSDE 399
Score = 47.8 bits (112), Expect = 0.008
Identities = 29/81 (35%), Positives = 37/81 (44%), Gaps = 4/81 (4%)
Frame = +1
Query: 10816 YTCSCPDQFVLLSDQKTCE----PNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEP 10983
+ C D SD++ CE P C QF CG + +CI + C+G DC DGSDE
Sbjct: 634 WRCDGEDDCSDNSDEENCENTGTPQCAPDQFLCG--NGRCIGQRKLCNGANDCGDGSDES 691
Query: 10984 GESICGQRICPVGEFQCTNHN 11046
C R GE C +N
Sbjct: 692 PHQNCRPR---TGEENCNVNN 709
Score = 39.7 bits (91), Expect = 2.2
Identities = 24/93 (25%), Positives = 50/93 (52%), Gaps = 3/93 (3%)
Frame = +1
Query: 13027 GRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDA 13206
G+I Y+D L I +D++G++ + ++ + + +A+D N +YW D V+
Sbjct: 1719 GKIYYTDVFLDV-IRRSDLNGSNMETVIGQGLKTTDGLAVDWVARN-LYWTDTGRNTVEV 1776
Query: 13207 VNIDGSERTTVVHDR-HIPYAVDVF--ENHIYW 13296
+DGS R ++++ P A+ VF + +++W
Sbjct: 1777 ARLDGSSRKVLINNSLDEPRAIAVFPKKGYLFW 1809
>gi|47117042|sp|O75096|LRP4_HUMAN Low-density lipoprotein
receptor-related protein 4 precursor (Multiple epidermal
growth factor-like domains 7)
Length = 1950
Score = 692 bits (1785), Expect = 0.0
Identities = 505/1743 (28%), Positives = 808/1743 (45%), Gaps = 33/1743 (1%)
Frame = +1
Query: 3160 CSSNSTQFQCKNGR-----CIPKEWKCDGENDCLDESDEIDEKGDKCFHETECAENTIKC 3324
C+ + F C CIP +W+CDG+NDC D SDE D C T C+ C
Sbjct: 70 CACGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDE-----DGCILPT-CSPLDFHC 123
Query: 3325 RNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNHRCIPEQWKXXXX 3504
N K CI +D C +F C N CI W
Sbjct: 124 DNGK-CIRRSWVCDGDNDCEDDSDE-----QDCPPRECEEDEFPCQNGYCIRSLWHCDGD 177
Query: 3505 XXXXXXXXEKLEMCGNATCAANQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERCPPV-- 3678
E+ +M C+ +F C++G CI +W CDGD DC DG+DE E CP
Sbjct: 178 NDCGDNSDEQCDM---RKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDE--ENCPSAVP 232
Query: 3679 --QCSALQFRCANGRQCVPLRNHXXXXXXXXXXXXXXXXAVTAESCTPDQFKCVSSGLCI 3852
C+ +F+CA GR C+ L + + + C +F C SGLCI
Sbjct: 233 APPCNLEEFQCAYGR-CI-LDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMC-DSGLCI 289
Query: 3853 PASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKCGNGRCILNNWLCDGENDCGDGSDE 4032
A W+ SDE CT+ C+++QF+C +GRC+ +W CDGE+DC D SDE
Sbjct: 290 NAGWRCDGDADCDDQSDERN--CTTS-MCTAEQFRCHSGRCVRLSWRCDGEDDCADNSDE 346
Query: 4033 SSERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGG------RCAR 4194
+ C+ + + +C + C N + CI +LC+G C +DE R
Sbjct: 347 EN---CENT-GSPQCALDQFLCWNGR--CIGQRKLCNGVNDCGDNSDESPQQNCRPRTGE 400
Query: 4195 DLCSADRAGCSFKCHNSPNGPICSCPFGEQLVNKTK-CEPENECLDSSSCSQRCKDEKHG 4371
+ C+ + GC+ KC C+C G +L C+ NEC + CSQ C + +
Sbjct: 401 ENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTEDGHTCQDVNECAEEGYCSQGCTNSEGA 460
Query: 4372 FTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGAIVENAIAL 4551
F C C+ GYEL D+R+CK + + +NR I + +ENAIAL
Sbjct: 461 FQCWCETGYELRPDRRSCKALG--PEPVLLFANRIDIRQVLPHRSEYTLLLNNLENAIAL 518
Query: 4552 AWDSLTDRIYWSDIREKKILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVDSSLN 4731
+ + ++WSD+ +IL AN NG+N ++ GL+ G+A+DWV LYW DS +
Sbjct: 519 DFHHRRELVFWSDVTLDRILRANLNGSNVEEVVSTGLESPGGLAVDWVHDKLYWTDSGTS 578
Query: 4732 TIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQNPCIERASMDGTDRQII 4911
IEVANL D R +L+ QN+ +PR IA+ P +G ++WTDWG P IE +SMDG+ R+II
Sbjct: 579 RIEVANL-DGAHRKVLLWQNLEKPRAIALHPMEGTIYWTDWGNTPRIEASSMDGSGRRII 637
Query: 4912 VKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFE 5091
T ++WPN + +DY R+Y+ D+K I+ N DGS R V+ S+ + HP A+ +FE
Sbjct: 638 ADTHLFWPNGLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVI--SQGLPHPFAITVFE 695
Query: 5092 DMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTN--P 5265
D +Y++D + + K+ G E + + + +HP QP KN C N
Sbjct: 696 DSLYWTDWHTKSINSANKF-TGKNQEIIRNKLHFPMDIHTLHPQRQPAGKNR-CGDNNGG 753
Query: 5266 CSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNVFGIEMNSASEKETP 5445
C+HLCL + +N +TC CP G + S C FL+ ++ ++ I ++ +
Sbjct: 754 CTHLCLPSGQN-YTCACPTGFR-KISSHACAQSLDKFLLFARRMDIRRISFDTEDLSD-- 809
Query: 5446 VLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNGGNKTKM 5625
++PL+ + +A +D+ + ++ ++TD+ I R+ +G + +
Sbjct: 810 ---DVIPLADVRSAVALDWDSRDDHVY----------WTDVSTDT-ISRAKWDGTGQEVV 855
Query: 5626 FSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVILSNDQSXXXXXXXXX 5805
+++ A L DW L + T IE+ T G +I N
Sbjct: 856 VDTSLESPA-GLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWEN------LDRPRD 908
Query: 5806 XXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAIDTTNTRVYFS 5985
GY++W D G A K+ RAG+D S VI S++L + +AID + R+Y++
Sbjct: 909 IVVEPMGGYMYWTDWG---ASPKIERAGMDASGRQVIISSNLTWPNGLAIDYGSQRLYWA 965
Query: 5986 EAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAFDSIEVA-TINGDSQP 6162
+A I DG R ++ P GL YG+R+++ D SI+ A + G +
Sbjct: 966 DAGMKTIEFAGLDGSKRKVLIGSQLPHPFGLTLYGERIYWTDWQTKSIQSADRLTGLDRE 1025
Query: 6163 PQWTHFKKDVENLANIKALQPRASSSGHPCHINNGNCDHICI----PLMFAQRTCTCANG 6330
++++ENL +I R PC + NG C H+C+ P F +CTC G
Sbjct: 1026 T----LQENLENLMDIHVFHRRRPPVSTPCAMENGGCSHLCLRSPNPSGF---SCTCPTG 1078
Query: 6331 --YVKDGQTSCKLFDESFVIVATKTKVIGYPIDETQSKGVAME-PIGGLSITGVDYDYES 6501
+ DG+T C SF+I A + + +D V + I + + D +
Sbjct: 1079 INLLSDGKT-CSPGMNSFLIFARRIDIRMVSLDIPYFADVVVPINITMKNTIAIGVDPQE 1137
Query: 6502 KTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINYNMYFINHDAERT 6681
+Y ++++ I+ + S +I + G T LA+D I +Y+ D
Sbjct: 1138 GKVYWSDST--LHRISRANLDGSQHEDII--TTGLQTTDGLAVDAIGRKVYWT--DTGTN 1191
Query: 6682 NIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQRSFLDGSRREVIV 6861
IEV LDG+ RK+L+ ++P +I + ++YW D G+ ++RS +DGS R V++
Sbjct: 1192 RIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTDWGENAKLERSGMDGSDRAVLI 1251
Query: 6862 SSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPELVRSDIASAAGVALHGQNMY 7041
++ + P L VD AS + W+DA + I G + S + G+ L +Y
Sbjct: 1252 NNNLGWPNGLTVDKASSQLLWADAHTERIEAADLNGANRHTLVSPVQHPYGLTLLDSYIY 1311
Query: 7042 WTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRASSPCQITDNLR 7221
WTD + + RA +L V ++L + D+ QP + C R
Sbjct: 1312 WTDWQTRSIHRADKGTGSNVIL-----VRSNLPGLMDMQAV-DRAQPLGFNKC----GSR 1361
Query: 7222 KSPCTQLCFATPGTQTPTCSCARGV-LK--GRTCE-EPDTYIMFSDGDKIIDVAIEPDVK 7389
C+ LC P +C+C G+ LK G+TC+ P+TY++FS I +++ D
Sbjct: 1362 NGGCSHLCLPRPSGF--SCACPTGIQLKGDGKTCDPSPETYLLFSSRGSIRRISL--DTS 1417
Query: 7390 ASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAENPRLVFGASKQP 7569
+ P PE++N+ + D D +VY+ + V +++ + N N V G
Sbjct: 1418 DHTDVHVPVPELNNVISLDYDSVDGKVYY---TDVFLDVIRRADLNGSNMETVIG----- 1469
Query: 7570 HAKEIRHISDMKLDWLTQKIYFT-TGRGG-KVMAIDTAGEHLSTIASGDWTYALAIDPCS 7743
+ ++ + +DW+ + +Y+T TGR + +D + + S D A+A+ P
Sbjct: 1470 --RGLKTTDGLAVDWVARNLYWTDTGRNTIEASRLDGSCRKVLINNSLDEPRAIAVFPRK 1527
Query: 7744 GLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVDFRNQKIYWADVN 7923
G LFW+D G+ +IER+NL G RKV+++ + P + +D+ ++IYW D +
Sbjct: 1528 GYLFWTDWGHIA-------KIERANLDGSERKVLINTDLGWPNGLTLDYDTRRIYWVDAH 1580
Query: 7924 RLNIEVADYDGQNRKVIASGY-RAKSLDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVS 8100
IE AD +G+ R+V+ S +L DRW+Y +D + + R+DK SG E V++
Sbjct: 1581 LDRIESADLNGKLRQVLVSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVLA 1640
Query: 8101 DRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLCTVVADDIGLAASKVQCS 8280
+ + G + + +T C +NGGC LC A D C+
Sbjct: 1641 N--VEGLMDIIVVSPQRQTGTNACG--------VNNGGCTHLCFARASDF-------VCA 1683
Query: 8281 CND 8289
C D
Sbjct: 1684 CPD 1686
Score = 463 bits (1191), Expect = e-128
Identities = 321/1036 (30%), Positives = 480/1036 (45%), Gaps = 57/1036 (5%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDT-----YTWH-- 315
C+ DF C++GKCIR W P C+ D++ C WH
Sbjct: 116 CSPLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPCQNGYCIRSLWHCD 175
Query: 316 --------------------------SVSCIAEYQRCDNITDCADGSDEKDCPASTV--D 411
SCIAE+ CD TDC DGSDE++CP++
Sbjct: 176 GDNDCGDNSDEQCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEENCPSAVPAPP 235
Query: 412 CSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQ 591
C+ + F CA GR D+ CDG DC D SDE D CS +H C +F C D CI
Sbjct: 236 CNLEE-FQCAYGRCILDIYH-CDGDDDCGDWSDESD-CS-SHQPCRSGEFMC-DSGLCIN 290
Query: 592 KSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDEC 771
W CDG DC D SDE + C CTA +F+C + RC +RCD DDC DNSDE+ C
Sbjct: 291 AGWRCDGDADCDDQSDERN-CTTSMCTAEQFRCHSGRCVRLSWRCDGEDDCADNSDEENC 349
Query: 772 ---GEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLG-------- 918
G +C ++ C G CI Q KLC+G DC D +DE QN P G
Sbjct: 350 ENTGSPQCALDQFLC-WNGRCIGQRKLCNGVNDCGDNSDESP-QQNCRPRTGEENCNVNN 407
Query: 919 --CQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCL 1092
C C +CTC +GY+L + H TC D+NECAE GYC Q C N F C C
Sbjct: 408 GGCAQKCQMVRGAVQCTCHTGYRLTEDGH-TCQDVNECAEEGYCSQGCTNSEGAFQCWC- 465
Query: 1093 GDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKLASGE 1272
G + R C + + + LF A R + ++ P E L + E
Sbjct: 466 ----------ETGYELRPDRRSCKALGPEPVLLF-ANRIDIRQVLPHR-SEYTLLLNNLE 513
Query: 1273 FIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNT 1452
+DF + +FW+D A+++ S ++++ L P LAVDW+ +
Sbjct: 514 NAIALDFHHRRELVFWSDVTLDRILRANLNG----SNVEEVVSTGLESPGGLAVDWVHDK 569
Query: 1453 LYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFT---NQLKLEAAAM 1623
LY +SG+ RI+V++ DG R VLL L P IAL P+ G +++T N ++EA++M
Sbjct: 570 LYWTDSGTSRIEVANLDGAHRKVLLWQNLEKPRAIALHPMEGTIYWTDWGNTPRIEASSM 629
Query: 1624 DGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRR-IVAQGMNVVP 1800
DG+ RR + +TH +G+ +D +R+YWVD K +E + G+ R+ +++QG+ P
Sbjct: 630 DGSGRRIIADTHLFWPNGLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVISQGL---P 686
Query: 1801 HPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPG 1980
HPF + +F+ LYWTDW + KF + + N + FPM I HP QP G
Sbjct: 687 HPFAITVFEDSLYWTDWHTKSINSANKFTGKNQEIIRNKLH--FPMDIHTLHPQRQPA-G 743
Query: 1981 QSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGKRCIDSID-YLL 2157
++ C N C +C+ S G Y CACP G + ++ C S+D +LL
Sbjct: 744 KNRC-------GDNNGGCTHLCLPS------GQNYTCACPTGFRKISSHACAQSLDKFLL 790
Query: 2158 FSSNKIVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIY 2337
F+ +R I + + L++ V+P++ + ++ D + ++ D+ +TI
Sbjct: 791 FARRMDIRRI--SFDTEDLSDDVIPLADVRSA-----VALDWDSRDDHVYWTDVSTDTIS 843
Query: 2338 RIRPDGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVR 2517
R + DG G V+ T + ++ DW++ +LY+ D + +EV + D +R
Sbjct: 844 RAKWDGTGQEVVVDTSLESPAGLAIDWVTNKLYWTDAGTDRIEV--------ANTDGSMR 895
Query: 2518 RQLITELRD-PVSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAI 2694
LI E D P +VV P G +++ + I R +D QVI ++ L P+ +AI
Sbjct: 896 TVLIWENLDRPRDIVVEPMGGYMYWTDWGASPKIERAGMDASGRQVIISSNLTWPNGLAI 955
Query: 2695 DFAENRLCWGDTLLKTISCMDFDG-KNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRR 2871
D+ RL W D +KTI DG K V + P P +T+ E IY+ + SI+
Sbjct: 956 DYGSQRLYWADAGMKTIEFAGLDGSKRKVLIGSQLPHPFGLTLYGERIYWTDWQTKSIQS 1015
Query: 2872 VHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQ--CTQLCFATPS 3045
+ G + ++E + ++ + + P+ PC C+ LC +P+
Sbjct: 1016 ADRLTGLDRETLQE---NLENLMDIHVFHRRRPPV-----STPCAMENGGCSHLCLRSPN 1067
Query: 3046 ESHPNELEAKCACRQG 3093
S C C G
Sbjct: 1068 PS-----GFSCTCPTG 1078
Score = 451 bits (1161), Expect = e-124
Identities = 268/762 (35%), Positives = 379/762 (49%), Gaps = 16/762 (2%)
Frame = +1
Query: 8617 ACAEGTFPCSNGH-----CINQTKVCDGHNDCHDEQVSDES-LATCPGLPIDCRGVKVRC 8778
AC F C+ CI CDG NDC D D L TC L C K
Sbjct: 71 ACGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDEDGCILPTCSPLDFHCDNGK--- 127
Query: 8779 PNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCIPETWQCDGDNDC 8958
CI+ + +CDG +DC D +DE C ++C + C +G CI W CDGDNDC
Sbjct: 128 -----CIRRSWVCDGDNDCEDDSDEQD--CPPRECEEDEFPCQNGYCIRSLWHCDGDNDC 180
Query: 8959 SDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXXXXXXHSRHGCGN 9138
D DE + C D F+C + CI+ + C +
Sbjct: 181 GDNSDEQ-------CDMRKC-SDKEFRCSDGSCIAEHWYCDGDTDCKDGS---DEENCPS 229
Query: 9139 RT----CTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECNK 9306
C +EF C CI + CDGD C DES C + + C
Sbjct: 230 AVPAPPCNLEEFQCAYG--------RCILDIYHCDGDDDCGDWSDESD--CSSHQP-CRS 278
Query: 9307 GEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCANHKCVPNSWKCDGN 9486
GEF C + CI++ W CDGD DC D SDE NCT S C + F+C + +CV SW+CDG
Sbjct: 279 GEFMCDSGLCINAGWRCDGDADCDDQSDER-NCTTSMCTAEQFRCHSGRCVRLSWRCDGE 337
Query: 9487 DDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLC 9666
DDC D SDE++C +N+ S Q C+ QF C +G CI K+C+ DC D SDES
Sbjct: 338 DDCADNSDEENC-ENTGSPQ----CALDQFLCWNGRCIGQRKLCNGVNDCGDNSDESPQQ 392
Query: 9667 FI------DECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNECYEGISG 9828
+ C++ C QKC ++ +C C G+ + D +C +VNEC E
Sbjct: 393 NCRPRTGEENCNVNNGG-CAQKCQMVRGAVQCTCHTGYRLT-EDGHTCQDVNECAEE-GY 449
Query: 9829 CSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNKYEL 10008
CSQ C + G+++C C GY+L D SCK + PEP L AN+ IR++ ++Y L
Sbjct: 450 CSQGCTNSEGAFQCWCETGYELRPDRRSCKA--LGPEPVLLFANRIDIRQVLPHRSEYTL 507
Query: 10009 AAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNVYGTEGIA 10188
+N ++LD + + D R+LR +L+ S+ E V+ + G+A
Sbjct: 508 LLNNLENAIALDFHHRRELVFWSDVTLDRILRANLNG-----SNVEEVVSTGLESPGGLA 562
Query: 10189 VDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFFTEWSLQP 10368
VDWV KLY + I V LDG K L+ +++P+AI +HP +G +++T+W P
Sbjct: 563 VDWVHDKLYWTDSGTSRIEVANLDGAHRKVLLWQNLEKPRAIALHPMEGTIYWTDWGNTP 622
Query: 10369 YIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGR 10548
I ++DGS +A+ L WPN + IDY R++W DA + I + DG+ R
Sbjct: 623 RIEASSMDGSGRRI-----IADTHLFWPNGLTIDYAGRRMYWVDAKHHVIERANLDGSHR 677
Query: 10549 RHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDLRIVHP 10728
+ + +Q H ++ VF+D LYW DW+ + + +K+TGKN+ I++ + P D+ +HP
Sbjct: 678 KAVISQGLPHPFAITVFEDSLYWTDWHTKSINSANKFTGKNQEIIRNKLHFPMDIHTLHP 737
Query: 10729 MRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLS 10854
RQPA N CGDNNGGC+HLCL G YTC+CP F +S
Sbjct: 738 QRQPAGKNRCGDNNGGCTHLCL--PSGQNYTCACPTGFRKIS 777
Score = 330 bits (845), Expect = 8e-88
Identities = 238/778 (30%), Positives = 343/778 (43%), Gaps = 47/778 (6%)
Frame = +1
Query: 11353 TPECAQIECKKGWTRCSSSY----RCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFR 11520
+PECA C + C+ S CIP C+G +DC D+SDED PTC + +F
Sbjct: 67 SPECA---CGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDEDGCILPTCSPL-DFH 122
Query: 11521 CATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGT 11700
C +GKCI R W+CD +NDC D+SDE D R C E EF C +G CI CDG
Sbjct: 123 C-DNGKCIRRSWVCDGDNDCEDDSDEQDCP----PRECEEDEFPCQNGYCIRSLWHCDGD 177
Query: 11701 IQCSDGLDESQCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCED-VSRRTC 11877
C D DE QC +R+C +C DG+CIAEH +CD DC + +DE +C V C
Sbjct: 178 NDCGDNSDE-QCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEENCPSAVPAPPC 236
Query: 11878 SPFEFECANSVCIPRKFMXXXXXXXXXXSDETSSE----CRSAQ--CDPPL--------- 12012
+ EF+CA CI + SDE+ CRS + CD L
Sbjct: 237 NLEEFQCAYGRCILDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMCDSGLCINAGWRCD 296
Query: 12013 ----------------------RFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSS 12126
+FRC HS C+ + C+G +DC N SDE C +
Sbjct: 297 GDADCDDQSDERNCTTSMCTAEQFRC-HSGRCVRLSWRCDGEDDCADN--SDEE--NCEN 351
Query: 12127 FSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEI---GCSKHGGKTSCEAFGNNG 12297
C+ DQF C NG+C+ C+ +DCGD SDE C G+ +C NNG
Sbjct: 352 TGS-PQCALDQFLCWNGRCIGQRKLCNGVNDCGDNSDESPQQNCRPRTGEENCNV--NNG 408
Query: 12298 GCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGSYLCRCHE 12477
GC C VR C C G+R + C D++ECA C+Q C N++G++ C C
Sbjct: 409 GCAQKCQMVRGAVQCTCHTGYRLT-EDGHTCQDVNECAEEGYCSQGCTNSEGAFQCWCET 467
Query: 12478 DYENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXX 12657
YE + C+A G ++ + Q+ H R
Sbjct: 468 GYELR-----PDRRSCKALGPEPVLLFANRIDIRQVLPH-----RSEYTLLLNNLENAIA 517
Query: 12658 XXXXPRKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTAIAVDYTTGNL 12837
R+EL++W S+ T+ R AN N S+ + + + P +AVD+ L
Sbjct: 518 LDFHHRRELVFW---SDVTLDRILRANLNGSNVEEVVSTGLES----PGGLAVDWVHDKL 570
Query: 12838 FIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITA 13017
+ + T I V DG + K ++ +L++P A+
Sbjct: 571 YWT-----------------------DSGTSRIEVANLDGAHRKVLLWQNLEKPRAIALH 607
Query: 13018 PSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRR 13197
P G I ++D G +IE + MDG+ R+II +F P + ID G R+YWVD K+
Sbjct: 608 PMEGTIYWTDWGNTPRIEASSMDGSGRRIIADTHLFWPNGLTIDYA-GRRMYWVDAKHHV 666
Query: 13198 VDAVNIDGSERTTVV-HDRHIPYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDL 13374
++ N+DGS R V+ P+A+ VFE+ +YW +K++ +KF ++ + L
Sbjct: 667 IERANLDGSHRKAVISQGLPHPFAITVFEDSLYWTDWHTKSINSANKFTGKNQEIIRNKL 726
Query: 13375 EDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPS-TGFACLCPDGIVPQLDGSCA 13545
+ + + G C+HLC LPS + C CP G +CA
Sbjct: 727 HFPMDIHTLHPQRQPAGKNRCGDNNGGCTHLC--LPSGQNYTCACPTGFRKISSHACA 782
Score = 244 bits (624), Expect = 3e-62
Identities = 195/732 (26%), Positives = 335/732 (45%), Gaps = 12/732 (1%)
Frame = +1
Query: 1018 NECAEF-GYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLF 1194
N C + G C LC +TC+C G K + + + + DK LF
Sbjct: 745 NRCGDNNGGCTHLCLPSGQNYTCAC---------PTGFRK----ISSHACAQSLDKFLLF 791
Query: 1195 VARREGLYRLNPKNPD--EEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDE 1368
ARR + R++ D ++V LA +D+D D ++WTD + A D
Sbjct: 792 -ARRMDIRRISFDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDGT 850
Query: 1369 GEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLP 1548
G+ + SL+S P LA+DW+TN LY ++G+ RI+V++ DG RTVL+ + L P
Sbjct: 851 GQ-EVVVDTSLES---PAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRP 906
Query: 1549 LDIALDPLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVD 1719
DI ++P+ G M++T+ K+E A MD + R+ +++++ +G+ +D ++R+YW D
Sbjct: 907 RDIVVEPMGGYMYWTDWGASPKIERAGMDASGRQVIISSNLTWPNGLAIDYGSQRLYWAD 966
Query: 1720 PKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKF-GSDT 1896
+ +E G+ R+++ +PHPFGL L+ + +YWTDW + ++ G D
Sbjct: 967 AGMKTIEFAGLDGSKRKVLIGSQ--LPHPFGLTLYGERIYWTDWQTKSIQSADRLTGLDR 1024
Query: 1897 KLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCT--NADCEGMCILSKDNGG 2070
+ L N EN M I +H P + PC N C +C+ S + G
Sbjct: 1025 ETLQENLEN---LMDIHVFHRRRPP-----------VSTPCAMENGGCSHLCLRSPNPSG 1070
Query: 2071 FGVGYKCACPIGQKLV-NGKRCIDSID-YLLFSSNKIVRGIFPEINEKALAEAVLPISPI 2244
F C CP G L+ +GK C ++ +L+F+ +R + +I A+ V+PI+
Sbjct: 1071 F----SCTCPTGINLLSDGKTCSPGMNSFLIFARRIDIRMVSLDI--PYFADVVVPINIT 1124
Query: 2245 SQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWIS 2424
+ I + D +++D + I R DG ++ T ++ D I
Sbjct: 1125 MKNTIA----IGVDPQEGKVYWSDSTLHRISRANLDGSQHEDIITTGLQTTDGLAVDAIG 1180
Query: 2425 KQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITE-LRDPVSVVVHPWKGLLFYAEAM 2601
+++Y+ D N +EV + D +R+ L+ + L P ++V++ G +++ +
Sbjct: 1181 RKVYWTDTGTNRIEVGNL--------DGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTDWG 1232
Query: 2602 RPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVK 2781
A + R +DG + V+ N LG P+ + +D A ++L W D + I D +G N
Sbjct: 1233 ENAKLERSGMDGSDRAVLINNNLGWPNGLTVDKASSQLLWADAHTERIEAADLNGANRHT 1292
Query: 2782 LDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSH 2961
L P +T+++ YIY+ + SI R K G +VR ++ L
Sbjct: 1293 LVSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKGTGSNVILVRS------NLPGLMDMQA 1346
Query: 2962 QNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINKENNHSCQKDPA 3141
++ P + R C+ LC PS CAC G + K + +C DP+
Sbjct: 1347 VDRAQPLGFNKCGSRNGGCSHLCLPRPS-------GFSCACPTGIQL-KGDGKTC--DPS 1396
Query: 3142 EKIEQLCSSNST 3177
+ L SS +
Sbjct: 1397 PETYLLFSSRGS 1408
Score = 228 bits (580), Expect = 4e-57
Identities = 195/701 (27%), Positives = 315/701 (44%), Gaps = 16/701 (2%)
Frame = +1
Query: 994 FHRTCSDINE-CA-EFGYCDQLCAN--HRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYC 1161
FHR ++ CA E G C LC + GF+C+C P NL G
Sbjct: 1040 FHRRRPPVSTPCAMENGGCSHLCLRSPNPSGFSCTC------------PTGINLLSDGKT 1087
Query: 1162 VSNNADKMKLFVARREGLYRLN---PKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRL 1332
S + +F ARR + ++ P D V + + I D + K++W+D
Sbjct: 1088 CSPGMNSFLIF-ARRIDIRMVSLDIPYFADVVVPINITMKNTIAIGVDPQEGKVYWSDST 1146
Query: 1333 AHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGER 1512
H A++D SQ + + L LAVD I +Y ++G+ RI+V + DG
Sbjct: 1147 LHRISRANLDG----SQHEDIITTGLQTTDGLAVDAIGRKVYWTDTGTNRIEVGNLDGSM 1202
Query: 1513 RTVLLADGLTLPLDIALDPLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHTHQVSGIV 1683
R VL+ L P I L G M++T+ KLE + MDG++R L+N + +G+
Sbjct: 1203 RKVLVWQNLDSPRAIVLYHEMGFMYWTDWGENAKLERSGMDGSDRAVLINNNLGWPNGLT 1262
Query: 1684 VDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLG 1863
VD + ++ W D +R+E+ D G +R + ++ V HP+GL L D Y+YWTDW
Sbjct: 1263 VDKASSQLLWADAHTERIEAADLNGANRHTL---VSPVQHPYGLTLLDSYIYWTDWQTRS 1319
Query: 1864 VIQVEK-FGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEG 2040
+ + +K GS+ L+ SN + + P+ G ++C + N C
Sbjct: 1320 IHRADKGTGSNVILVRSNLPGLMDMQAVDRAQPL-----GFNKCGSR-------NGGCSH 1367
Query: 2041 MCILSKDNGGFGVGYKCACPIGQKLV-NGKRCIDSID-YLLFSSNKIVRGIFPEINEKAL 2214
+C+ G+ CACP G +L +GK C S + YLLFSS +R I + ++
Sbjct: 1368 LCLPRPS------GFSCACPTGIQLKGDGKTCDPSPETYLLFSSRGSIRRISLDTSDHTD 1421
Query: 2215 AEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDG 2394
+P + ++ D +Y D+ + I R +G V+
Sbjct: 1422 VHVPVP-------ELNNVISLDYDSVDGKVYYTDVFLDVIRRADLNGSNMETVIGRGLKT 1474
Query: 2395 LFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITE-LRDPVSVVVHPW 2571
++ DW+++ LY+ D RN++E ++ D R+ LI L +P ++ V P
Sbjct: 1475 TDGLAVDWVARNLYWTDTGRNTIEASRL--------DGSCRKVLINNSLDEPRAIAVFPR 1526
Query: 2572 KGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISC 2751
KG LF+ + A I R ++DG +V+ NT LG P+ + +D+ R+ W D L I
Sbjct: 1527 KGYLFWTDWGHIAKIERANLDGSERKVLINTDLGWPNGLTLDYDTRRIYWVDAHLDRIES 1586
Query: 2752 MDFDGKNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADER 2931
D +GK L P A+T + +IY+ + SI+RV K +G + V A+
Sbjct: 1587 ADLNGKLRQVLVSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVL---ANVE 1643
Query: 2932 SIFSLKACSHQNQPIPDDSREHPCRASQ--CTQLCFATPSE 3048
+ + S Q Q + + C + CT LCFA S+
Sbjct: 1644 GLMDIIVVSPQRQ-----TGTNACGVNNGGCTHLCFARASD 1679
Score = 225 bits (574), Expect = 2e-56
Identities = 125/349 (35%), Positives = 184/349 (51%), Gaps = 3/349 (0%)
Frame = +1
Query: 9802 NECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKI 9981
N+C GCS C + + C C G QL D +C + PE + L +++ IR+I
Sbjct: 1356 NKCGSRNGGCSHLCLPRPSGFSCACPTGIQLKGDGKTC---DPSPETYLLFSSRGSIRRI 1412
Query: 9982 SIDGNKY---ELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETV 10152
S+D + + + +NV+SLD D + K Y D + R DL+ S+ ETV
Sbjct: 1413 SLDTSDHTDVHVPVPELNNVISLDYDSVDGKVYYTDVFLDVIRRADLNG-----SNMETV 1467
Query: 10153 LRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGK 10332
+ + T+G+AVDWV R LY + +I LDG K LI + + +P+AI V P K
Sbjct: 1468 IGRGLKTTDGLAVDWVARNLYWTDTGRNTIEASRLDGSCRKVLINNSLDEPRAIAVFPRK 1527
Query: 10333 GYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLN 10512
GYLF+T+W I R LDGS L DLGWPN + +DY + R++W DAHL+
Sbjct: 1528 GYLFWTDWGHIAKIERANLDGSERK-----VLINTDLGWPNGLTLDYDTRRIYWVDAHLD 1582
Query: 10513 EIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKT 10692
I D +G R + SH ++ D ++YW DW + + R DK++G+N+ +
Sbjct: 1583 RIESADLNGK-LRQVLVSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVLAN 1641
Query: 10693 VQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQ 10839
V+ D+ +V P RQ N CG NNGGC+HLC A + + C+CPD+
Sbjct: 1642 VEGLMDIIVVSPQRQTG-TNACGVNNGGCTHLCF--ARASDFVCACPDE 1687
Score = 201 bits (510), Expect = 6e-49
Identities = 113/361 (31%), Positives = 174/361 (47%), Gaps = 3/361 (0%)
Frame = +1
Query: 9802 NECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKI 9981
N C + GC+ C +Y C C G++ S H+C ++ + F L A + IR+I
Sbjct: 745 NRCGDNNGGCTHLCLPSGQNYTCACPTGFRKISS-HACAQSL---DKFLLFARRMDIRRI 800
Query: 9982 SIDGNKYE---LAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETV 10152
S D + + V+LD D + Y D + R D + E V
Sbjct: 801 SFDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDG-----TGQEVV 855
Query: 10153 LRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGK 10332
+ ++ G+A+DWV KLY + I V DG LI + + +P+ IVV P
Sbjct: 856 VDTSLESPAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRPRDIVVEPMG 915
Query: 10333 GYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLN 10512
GY+++T+W P I R +D S + +L WPN +AIDY S RL+W DA +
Sbjct: 916 GYMYWTDWGASPKIERAGMDASGRQV-----IISSNLTWPNGLAIDYGSQRLYWADAGMK 970
Query: 10513 EIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKT 10692
I F DG+ R+ + + H + ++ + +YW DW + + D+ TG + L++
Sbjct: 971 TIEFAGLDGSKRKVLIGSQLPHPFGLTLYGERIYWTDWQTKSIQSADRLTGLDRETLQEN 1030
Query: 10693 VQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTCE 10872
++ D+ + H R+P PC NGGCSHLCL +G++C+CP LLSD KTC
Sbjct: 1031 LENLMDIHVFH-RRRPPVSTPCAMENGGCSHLCLRSPNPSGFSCTCPTGINLLSDGKTCS 1089
Query: 10873 P 10875
P
Sbjct: 1090 P 1090
Score = 194 bits (494), Expect = 4e-47
Identities = 114/357 (31%), Positives = 171/357 (46%), Gaps = 6/357 (1%)
Frame = +1
Query: 9826 GCSQKC--DDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNK 9999
GCS C + C C G L SD +C F + A + IR +S+D
Sbjct: 1057 GCSHLCLRSPNPSGFSCTCPTGINLLSDGKTCSPGM---NSFLIFARRIDIRMVSLDIPY 1113
Query: 10000 YELAAQGFD----NVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNV 10167
+ + N +++ +D E K Y D R+ R +LD S +E ++ +
Sbjct: 1114 FADVVVPINITMKNTIAIGVDPQEGKVYWSDSTLHRISRANLDG-----SQHEDIITTGL 1168
Query: 10168 YGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFF 10347
T+G+AVD +GRK+Y + I V LDG K L+ + P+AIV++ G++++
Sbjct: 1169 QTTDGLAVDAIGRKVYWTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYW 1228
Query: 10348 TEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFM 10527
T+W + R +DGS L ++LGWPN + +D S +L W DAH I
Sbjct: 1229 TDWGENAKLERSGMDGSDRA-----VLINNNLGWPNGLTVDKASSQLLWADAHTERIEAA 1283
Query: 10528 DFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPN 10707
D +G RH H + + D Y+YW DW R + R DK TG N +++ +
Sbjct: 1284 DLNG-ANRHTLVSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKGTGSNVILVRSNLPGLM 1342
Query: 10708 DLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTCEPN 10878
D++ V QP N CG NGGCSHLCL +G++C+CP L D KTC+P+
Sbjct: 1343 DMQAV-DRAQPLGFNKCGSRNGGCSHLCL--PRPSGFSCACPTGIQLKGDGKTCDPS 1396
Score = 158 bits (399), Expect = 4e-36
Identities = 115/372 (30%), Positives = 155/372 (40%), Gaps = 19/372 (5%)
Frame = +1
Query: 8383 PYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCN 8562
P +F C +G CI CD DC D SDE C R C ED C N CI S C+
Sbjct: 118 PLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQD--CPPRECEEDEFPCQNGYCIRSLWHCD 175
Query: 8563 HIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPG 8742
+DCGD SDE C C++ F CS+G CI + CDG DC D + + P
Sbjct: 176 GDNDCGDNSDE-QCDMR-KCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEENCPSAVPA 233
Query: 8743 LPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCI 8922
P C + +C CI CDG DDCGD +DE+ +Q C C SG CI
Sbjct: 234 PP--CNLEEFQCAYGR-CILDIYHCDGDDDCGDWSDESDC-SSHQPCRSGEFMCDSGLCI 289
Query: 8923 PETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXX 9102
W+CDGD DC D DE NCT + +C + F+C + +C+ ++
Sbjct: 290 NAGWRCDGDADCDDQSDE--RNCTTS----MCTAEQ-FRCHSGRCVRLSWRCDGEDDCAD 342
Query: 9103 XXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTEL-C 9279
+ G+ C +F C + CI + LC+G C DES + C
Sbjct: 343 NSDEENCENTGSPQCALDQFLCWNG--------RCIGQRKLCNGVNDCGDNSDESPQQNC 394
Query: 9280 --KTEKKECNKGEFRCSN---------QHCIHSTWE-------CDGDNDCLDGSDEHANC 9405
+T ++ CN C+ Q H+ + C N+C + C
Sbjct: 395 RPRTGEENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTEDGHTCQDVNECAEEGYCSQGC 454
Query: 9406 TYSSCQPDFFQC 9441
T S FQC
Sbjct: 455 TNSE---GAFQC 463
Score = 151 bits (381), Expect = 5e-34
Identities = 102/316 (32%), Positives = 132/316 (41%), Gaps = 4/316 (1%)
Frame = +1
Query: 10852 SDQKTCE-PNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEF 11028
SD+ C P C+ F C D+ KCI + W CDG+ DC D SDE C R C EF
Sbjct: 106 SDEDGCILPTCSPLDFHC--DNGKCIRRSWVCDGDNDCEDDSDEQD---CPPRECEEDEF 160
Query: 11029 QCTNHNCTRPFQIXXXXXXXXXXXXEQNCDKACDPWMFKCAATGRCIPRRFTXXXXXXXX 11208
C N C R EQ + C F+C + G CI +
Sbjct: 161 PCQNGYCIRSLWHCDGDNDCGDNSDEQCDMRKCSDKEFRC-SDGSCIAEHWYCDGDTDCK 219
Query: 11209 XRSDEADTLCMSAERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXETPECAQIECKKG 11388
SDE + C EEF+C +CI + E+ + C+ G
Sbjct: 220 DGSDEENCPSAVPAPPCNLEEFQCAYGRCILDIYHCDGDDDCGDWSDESDCSSHQPCRSG 279
Query: 11389 WTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMCDT 11568
C S W C+G DC D SDE C +FRC SG+C+ W CD
Sbjct: 280 EFMCDSGLCINAGWR-CDGDADCDDQSDERNCTTSMC-TAEQFRC-HSGRCVRLSWRCDG 336
Query: 11569 ENDCGDNSDELDASCGGTTRP-CSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTLR 11745
E+DC DNSDE +C T P C+ +F C +G+CI K+C+G C D DES
Sbjct: 337 EDDCADNSDE--ENCENTGSPQCALDQFLCWNGRCIGQRKLCNGVNDCGDNSDESPQQNC 394
Query: 11746 RCLPGHRQC--DDGTC 11787
R G C ++G C
Sbjct: 395 RPRTGEENCNVNNGGC 410
Score = 149 bits (377), Expect = 1e-33
Identities = 109/340 (32%), Positives = 148/340 (43%), Gaps = 10/340 (2%)
Frame = +1
Query: 8362 PAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCI 8541
P +EC F C +G CI CD DC D SDE C+ R C + C++ CI
Sbjct: 151 PPRECEED-EFPCQNGYCIRSLWHCDGDNDCGDNSDEQ---CDMRKCSDKEFRCSDGSCI 206
Query: 8542 DSAKKCNHIDDCGDGSDELDCPSAV---ACAEGTFPCSNGHCINQTKVCDGHNDCHDEQV 8712
C+ DC DGSDE +CPSAV C F C+ G CI CDG +DC D
Sbjct: 207 AEHWYCDGDTDCKDGSDEENCPSAVPAPPCNLEEFQCAYGRCILDIYHCDGDDDCGD--W 264
Query: 8713 SDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQH 8892
SDES + CR + C ++ +CI CDG DC D++DE C C
Sbjct: 265 SDESDCSSHQ---PCRSGEFMC-DSGLCINAGWRCDGDADCDDQSDERN--CTTSMCTAE 318
Query: 8893 YVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAF 9072
RC SGRC+ +W+CDG++DC+D DE NC +T + + +L C N +CI +
Sbjct: 319 QFRCHSGRCVRLSWRCDGEDDCADNSDE--ENCENTGSPQCALDQFL--CWNGRCIGQRK 374
Query: 9073 IXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAG 9252
+ + C RT E +C N K + + A C TC
Sbjct: 375 LCNGVNDCGDNSDESPQQNCRPRT---GEENCNVNNGGCAQKCQMVRGAVQC----TCHT 427
Query: 9253 GE--DESTELCK-----TEKKECNKGEFRCSNQHCIHSTW 9351
G E C+ E+ C++G C+N W
Sbjct: 428 GYRLTEDGHTCQDVNECAEEGYCSQG---CTNSEGAFQCW 464
Score = 142 bits (357), Expect = 3e-31
Identities = 105/370 (28%), Positives = 174/370 (46%), Gaps = 9/370 (2%)
Frame = +1
Query: 1018 NEC-AEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLF 1194
N+C + G C LC GF+C+C +Q++ G GK + + + L
Sbjct: 1356 NKCGSRNGGCSHLCLPRPSGFSCACPTG---IQLK-GDGK---------TCDPSPETYLL 1402
Query: 1195 VARREGLYRLNPKNPDEEVKKLASGEF--IYGIDFDYGDRKIFWTDRLAHSAFSADVDDE 1368
+ R + R++ D + E + +D+D D K+++TD AD++
Sbjct: 1403 FSSRGSIRRISLDTSDHTDVHVPVPELNNVISLDYDSVDGKVYYTDVFLDVIRRADLNG- 1461
Query: 1369 GEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLP 1548
S ++ + + L LAVDW+ LY ++G I+ S DG R VL+ + L P
Sbjct: 1462 ---SNMETVIGRGLKTTDGLAVDWVARNLYWTDTGRNTIEASRLDGSCRKVLINNSLDEP 1518
Query: 1549 LDIALDPLRGEMFFTNQ---LKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVD 1719
IA+ P +G +F+T+ K+E A +DG+ R+ L+NT +G+ +D +R+YWVD
Sbjct: 1519 RAIAVFPRKGYLFWTDWGHIAKIERANLDGSERKVLINTDLGWPNGLTLDYDTRRIYWVD 1578
Query: 1720 PKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKF-GSDT 1896
+DR+ES D G R+++ ++ V HPF L D+++YWTDW + +V+K+ G +
Sbjct: 1579 AHLDRIESADLNGKLRQVL---VSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNK 1635
Query: 1897 KLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPC--TNADCEGMCILSKDNGG 2070
+ + +N E M I P Q G N C N C +C +
Sbjct: 1636 ETVLANVEG---LMDIIVVSPQRQTG-----------TNACGVNNGGCTHLCFARASD-- 1679
Query: 2071 FGVGYKCACP 2100
+ CACP
Sbjct: 1680 ----FVCACP 1685
Score = 130 bits (328), Expect = 7e-28
Identities = 100/350 (28%), Positives = 145/350 (40%), Gaps = 16/350 (4%)
Frame = +1
Query: 10852 SDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPG-ESICGQRICPVGEF 11028
SD++ C++++F C D CI + WYCDG+ DC+DGSDE S C + EF
Sbjct: 184 SDEQCDMRKCSDKEFRCS--DGSCIAEHWYCDGDTDCKDGSDEENCPSAVPAPPCNLEEF 241
Query: 11029 QCTNHNCTRPFQIXXXXXXXXXXXXEQNCD--KACDPWMFKCAATGRCIPRRFTXXXXXX 11202
QC C E +C + C F C +G CI +
Sbjct: 242 QCAYGRCILDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMC-DSGLCINAGWRCDGDAD 300
Query: 11203 XXXRSDEADTLCMSAERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXETPECAQIECK 11382
+SDE + C ++ CTAE+FRC++ +C+ +WR
Sbjct: 301 CDDQSDERN--CTTS--MCTAEQFRCHSGRCVRLSWR----------------------- 333
Query: 11383 KGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCAT------SGKCI 11544
C+G+DDC DNSDE+ C++ G +CA +G+CI
Sbjct: 334 ------------------CDGEDDCADNSDEE-----NCENTGSPQCALDQFLCWNGRCI 370
Query: 11545 PRRWMCDTENDCGDNSDELDASCGGTTRP-CSESEFRCNDGKCIPGSKVCDGTIQCSDGL 11721
+R +C+ NDCGDNSDE S RP E N+G C ++ G +QC+
Sbjct: 371 GQRKLCNGVNDCGDNSDE---SPQQNCRPRTGEENCNVNNGGCAQKCQMVRGAVQCT--- 424
Query: 11722 DESQCTLRRCLPGHRQCDDG-TC-----IAEHKWCDRKKDCPNAADELHC 11853
C G+R +DG TC AE +C + C N+ C
Sbjct: 425 ---------CHTGYRLTEDGHTCQDVNECAEEGYC--SQGCTNSEGAFQC 463
Score = 105 bits (262), Expect = 3e-20
Identities = 92/382 (24%), Positives = 155/382 (40%), Gaps = 3/382 (0%)
Frame = +1
Query: 12400 DECAGNNT-CTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDSL 12576
+ C NN CT LCL + +Y C C + ++ C D + D +
Sbjct: 745 NRCGDNNGGCTHLCLPSGQNYTCACPTGFRK------ISSHACAQSLDKFLLFARRMD-I 797
Query: 12577 VQLSLHGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERTIYRSAIANGNQSHE 12756
++S + R + +YW D S TI R+
Sbjct: 798 RRISFDTEDLSDDVIPLADVRSAVALDWDS--RDDHVYWTDVSTDTISRA-----KWDGT 850
Query: 12757 GQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFI 12936
GQ++ VD + P +A+D+ T L+ + T I
Sbjct: 851 GQEVVVDTSLES--PAGLAIDWVTNKLYWT-----------------------DAGTDRI 885
Query: 12937 FVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKD 13116
V DG ++ +L +P ++ P G + ++D G KIE A MD + RQ+I+
Sbjct: 886 EVANTDGSMRTVLIWENLDRPRDIVVEPMGGYMYWTDWGASPKIERAGMDASGRQVIISS 945
Query: 13117 LVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDR-HIPYAVDVFENHIY 13293
+ P +AID G R+YW D + ++ +DGS+R ++ + P+ + ++ IY
Sbjct: 946 NLTWPNGLAIDYG-SQRLYWADAGMKTIEFAGLDGSKRKVLIGSQLPHPFGLTLYGERIY 1004
Query: 13294 WLSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCV 13473
W ++K++ D+ L +LE+ + V + + T E CSHLC+
Sbjct: 1005 WTDWQTKSIQSADRLTGLDRETLQENLENLMDIHVFHR-RRPPVSTPCAMENGGCSHLCL 1063
Query: 13474 SLPS-TGFACLCPDGIVPQLDG 13536
P+ +GF+C CP GI DG
Sbjct: 1064 RSPNPSGFSCTCPTGINLLSDG 1085
Score = 102 bits (254), Expect = 3e-19
Identities = 57/162 (35%), Positives = 74/162 (45%), Gaps = 5/162 (3%)
Frame = +1
Query: 505 SDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEF 684
S + +C R+H C + CI W CDG DC D SDE D C C+ +F
Sbjct: 66 SSPECACGRSHFTC---AVSALGECTCIPAQWQCDGDNDCGDHSDE-DGCILPTCSPLDF 121
Query: 685 QCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDC 864
C N +C R + CD +DC D+SDE +C C ++ C G+CI L CDG DC
Sbjct: 122 HCDNGKCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPCQ-NGYCIRSLWHCDGDNDC 180
Query: 865 ADGADEQQCSQNLC--PSLGCQAGCHPSPH---GGECTCPSG 975
D +DE QC C C G + H G+ C G
Sbjct: 181 GDNSDE-QCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDG 221
Score = 99.4 bits (246), Expect = 2e-18
Identities = 55/195 (28%), Positives = 105/195 (53%)
Frame = +1
Query: 12952 DGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSP 13131
DG K +V +L P A++ G + ++D G +AK+E + MDG+ R +++ + + P
Sbjct: 1199 DGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTDWGENAKLERSGMDGSDRAVLINNNLGWP 1258
Query: 13132 TSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSRES 13311
+ +D+ +++ W D R++A +++G+ R T+V PY + + +++IYW ++
Sbjct: 1259 NGLTVDKAS-SQLLWADAHTERIEAADLNGANRHTLVSPVQHPYGLTLLDSYIYWTDWQT 1317
Query: 13312 KTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTG 13491
++++ DK V ++ S+L ++ + A+ G CSHLC+ PS G
Sbjct: 1318 RSIHRADKGTGSNVILVRSNLPGLMDMQAVDR-AQPLGFNKCGSRNGGCSHLCLPRPS-G 1375
Query: 13492 FACLCPDGIVPQLDG 13536
F+C CP GI + DG
Sbjct: 1376 FSCACPTGIQLKGDG 1390
Score = 93.2 bits (230), Expect = 2e-16
Identities = 56/188 (29%), Positives = 96/188 (50%), Gaps = 1/188 (0%)
Frame = +1
Query: 12952 DGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSP 13131
DG K ++ L +P A+ P G + ++D G AKIE A++DG+ R++++ + P
Sbjct: 1503 DGSCRKVLINNSLDEPRAIAVFPRKGYLFWTDWGHIAKIERANLDGSERKVLINTDLGWP 1562
Query: 13132 TSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSRES 13311
+ +D RIYWVD R+++ +++G R +V P+A+ + IYW ++
Sbjct: 1563 NGLTLDYDT-RRIYWVDAHLDRIESADLNGKLRQVLVSHVSHPFALTQQDRWIYWTDWQT 1621
Query: 13312 KTLYVQDKF-GRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPST 13488
K++ DK+ GR + +VLA+ +G + + T G C+HLC + S
Sbjct: 1622 KSIQRVDKYSGRNKETVLAN--VEGLMDIIVVSPQRQTGTNACGVNNGGCTHLCFARAS- 1678
Query: 13489 GFACLCPD 13512
F C CPD
Sbjct: 1679 DFVCACPD 1686
Score = 64.3 bits (155), Expect = 8e-08
Identities = 52/205 (25%), Positives = 75/205 (36%), Gaps = 21/205 (10%)
Frame = +1
Query: 139 NTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHS 318
N +S+C FRC+ G+C+R W
Sbjct: 309 NCTTSMCTAEQFRCHSGRCVRLSW------------------------------------ 332
Query: 319 VSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCR 498
RCD DCAD SDE++C + + + F+C +GR C K C+G DC
Sbjct: 333 --------RCDGEDDCADNSDEENCENTGSPQCALDQFLCWNGR-CIGQRKLCNGVNDCG 383
Query: 499 DLSDE-----------KDSCSRNHTACFQ--------YQFRCADKTQCIQKSWVCDGSKD 621
D SDE +++C+ N+ C Q Q C + + C +
Sbjct: 384 DNSDESPQQNCRPRTGEENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTEDGHTCQDVNE 443
Query: 622 CADGSDEPDTCEFKKCTANE--FQC 690
CA E C + CT +E FQC
Sbjct: 444 CA----EEGYCS-QGCTNSEGAFQC 463
Score = 59.3 bits (142), Expect = 3e-06
Identities = 35/101 (34%), Positives = 43/101 (41%), Gaps = 2/101 (1%)
Frame = +1
Query: 10753 PCGDNNGGC-SHLCLIGAGGNGYTCSCPDQFVLLSDQKTCEPN-CTERQFACGGDDAKCI 10926
PC C S LC+ C DQ SD++ C + CT QF C +C+
Sbjct: 275 PCRSGEFMCDSGLCINAGWRCDGDADCDDQ----SDERNCTTSMCTAEQFRC--HSGRCV 328
Query: 10927 PKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNC 11049
W CDGE DC D SDE G C + +F C N C
Sbjct: 329 RLSWRCDGEDDCADNSDEENCENTGSPQCALDQFLCWNGRC 369
Score = 52.8 bits (125), Expect = 2e-04
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 6/105 (5%)
Frame = +1
Query: 3049 SHPNELEAKCACRQGFMINK----ENNHSCQKDPAEKIEQLCSSNSTQFQCKNGRCIPKE 3216
SH + C G IN + + C E+ + QF+C +GRC+
Sbjct: 272 SHQPCRSGEFMCDSGLCINAGWRCDGDADCDDQSDERNCTTSMCTAEQFRCHSGRCVRLS 331
Query: 3217 WKCDGENDCLDESDEIDEKGDKCFH--ETECAENTIKCRNTKKCI 3345
W+CDGE+DC D SDE + C + +CA + C N +CI
Sbjct: 332 WRCDGEDDCADNSDE-----ENCENTGSPQCALDQFLCWN-GRCI 370
Score = 49.7 bits (117), Expect = 0.002
Identities = 29/106 (27%), Positives = 57/106 (53%), Gaps = 3/106 (2%)
Frame = +1
Query: 12988 LQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNR 13167
++ A+ P G++ +SD+ LH +I A++DG+ + I+ + + +A+D G +
Sbjct: 1125 MKNTIAIGVDPQEGKVYWSDSTLH-RISRANLDGSQHEDIITTGLQTTDGLAVD-AIGRK 1182
Query: 13168 IYWVDPKYRRVDAVNIDGSERTTVV-HDRHIPYAVDVFE--NHIYW 13296
+YW D R++ N+DGS R +V + P A+ ++ +YW
Sbjct: 1183 VYWTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYW 1228
Score = 38.5 bits (88), Expect = 4.9
Identities = 24/93 (25%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
Frame = +1
Query: 13027 GRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDA 13206
G++ Y+D L I AD++G++ + ++ + + +A+D N +YW D ++A
Sbjct: 1442 GKVYYTDVFLDV-IRRADLNGSNMETVIGRGLKTTDGLAVDWVARN-LYWTDTGRNTIEA 1499
Query: 13207 VNIDGSERTTVVHDR-HIPYAVDVF--ENHIYW 13296
+DGS R ++++ P A+ VF + +++W
Sbjct: 1500 SRLDGSCRKVLINNSLDEPRAIAVFPRKGYLFW 1532
>gi|47271362|ref|NP_112612.1| low density lipoprotein receptor-related
protein 4 [Rattus norvegicus]
gi|47076317|dbj|BAD18061.1| LDL receptor-related protein 13 [Rattus
norvegicus]
Length = 1905
Score = 687 bits (1773), Expect = 0.0
Identities = 505/1764 (28%), Positives = 810/1764 (45%), Gaps = 42/1764 (2%)
Frame = +1
Query: 3124 CQKDPAEKIEQLCSSNSTQFQCKNGR-----CIPKEWKCDGENDCLDESDEIDEKGDKCF 3288
C A +E C+ + F C CIP +W+CDG+NDC D SDE D C
Sbjct: 15 CAHGTASNLE--CACGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDE-----DGCT 67
Query: 3289 HETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNH 3468
T C+ C N K CI +D C +F C N
Sbjct: 68 LPT-CSPLDFHCDNGK-CIRRSWVCDGDNDCEDDSDE-----QDCPPRECEEDEFPCQNG 120
Query: 3469 RCIPEQWKXXXXXXXXXXXXEKLEMCGNATCAANQFSCANGRCIPIYWLCDGDNDCYDGT 3648
CI W E+ +M C+ +F C++G CI +W CDGD DC DG+
Sbjct: 121 YCIRSLWHCDGDNDCGDNSDEQCDM---RKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGS 177
Query: 3649 DEDK--ERCPPVQCSALQFRCANGRQCVPLRNHXXXXXXXXXXXXXXXXAVTAESCTPDQ 3822
DE+ P C+ +F+CA GR+ + + + + + C +
Sbjct: 178 DEESCPSAVPSPPCNLEEFQCAYGRRILDI--YHCDGDDDCGDWSDESDCSSHQPCRSGE 235
Query: 3823 FKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKCGNGRCILNNWLCDG 4002
F C SGLC+ A W+ SDE CT+ C+++QF+C +GRC+ +W CDG
Sbjct: 236 FMC-DSGLCVNAGWRCDGDADCDDQSDERN--CTTS-MCTAEQFRCRSGRCVRLSWRCDG 291
Query: 4003 ENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGG 4182
E+DC D SDE + C+ + + +C + C N + CI +LC+G C +DE
Sbjct: 292 EDDCADNSDEEN---CENT-GSPQCASDQFLCWNGR--CIGQRKLCNGVNDCGDNSDESP 345
Query: 4183 ------RCARDLCSADRAGCSFKCHNSPNGPICSCPFGEQLVNKTK-CEPENECLDSSSC 4341
R + C+ + GC+ KC C+C G +L + C+ NEC + C
Sbjct: 346 QQNCRPRTGEENCNVNNGGCAQKCQMIRGAVQCTCHTGYRLTEDGRTCQDVNECAEEGYC 405
Query: 4342 SQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTF 4521
SQ C + + F C C+ GYEL D+R CK + + +NR I +
Sbjct: 406 SQGCTNSEGAFQCRCEAGYELRPDRRNCKALG--PEPVLLFANRIDIRQVLPHRSEYTLL 463
Query: 4522 GAIVENAIALAWDSLTDRIYWSDIREKKILSANRNGTNATVFIADGLDITEGIALDWVGR 4701
+ENAIAL + + ++WSD+ +IL AN NG+N ++ GL+ G+A+DWV
Sbjct: 464 LNNLENAIALDFHHRRELVFWSDVTLDRILRANLNGSNVEEVVSTGLESPGGLAVDWVHD 523
Query: 4702 NLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQNPCIERA 4881
LYW DS + IEVANL D R +L+ Q++ +PR IA+ P +G ++WTDWG P IE +
Sbjct: 524 KLYWTDSGTSRIEVANL-DGAHRKVLLWQSLEKPRAIALHPMEGTIYWTDWGNTPRIEAS 582
Query: 4882 SMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFV 5061
SMDG+ R+II T ++WPN + +DY R+Y+ D+K I+ N DGS R V+ S+ +
Sbjct: 583 SMDGSGRRIIADTHLFWPNGLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVI--SQGL 640
Query: 5062 QHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIK 5241
HP A+ +FED +Y++D + + K+ G E + + + +HP QP K
Sbjct: 641 PHPFAITVFEDSLYWTDWHTKSINSANKF-TGKNQEIIRNKLHFPMDIHTLHPQRQPAGK 699
Query: 5242 NNPCSTN--PCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNVFGIE 5415
N C N C+HLCL + +N +TC CP G + + C FL+ ++ ++ I
Sbjct: 700 NR-CGDNNGGCTHLCLPSGQN-YTCACPTGFR-KINSHACAQSLDKFLLFARRMDIRRIS 756
Query: 5416 MNSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRS 5595
++ + ++PL+ + +A +D+ + ++ ++TD+ I R+
Sbjct: 757 FDTEDLSD-----DVIPLADVRSAVALDWDSRDDHVY----------WTDVSTDT-ISRA 800
Query: 5596 TVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVILSNDQ 5775
+G + + +++ A L DW L + T IE+ T G +I N
Sbjct: 801 KWDGTGQKVVVDTSLESPA-GLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWEN-- 857
Query: 5776 SXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAI 5955
GY++W D G A K+ RAG+D SN VI S++L + +AI
Sbjct: 858 ----LDRPRDIVVEPMGGYMYWTDWG---ASPKIERAGMDASNRQVIISSNLTWPNGLAI 910
Query: 5956 DTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAFDSIEV 6135
D + R+Y+++A I DG R ++ P GL YG R+++ D SI+
Sbjct: 911 DYGSQRLYWADAGMKTIEFAGLDGSKRKVLIGSQLPHPFGLTLYGQRIYWTDWQTKSIQS 970
Query: 6136 A-TINGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHINNGNCDHICI----PLMF 6300
A + G + ++++ENL +I + PC + NG C H+C+ P F
Sbjct: 971 ADRLTGLDRET----LQENLENLMDIHVFHRQRPPVTTPCAVENGGCSHLCLRSPSPSGF 1026
Query: 6301 AQRTCTCANG--YVKDGQTSCKLFDESFVIVATKTKV------------IGYPIDETQSK 6438
+CTC G + DG+T C SF+I A + V + PI+ T
Sbjct: 1027 ---SCTCPTGINLLLDGKT-CSPGMNSFLIFARRIDVRMVSLDIPYFADVVVPINMTMKN 1082
Query: 6439 GVAMEPIGGLSITGVDYDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIK 6618
+A IG + G Y +S ++ AS + S +I + G T
Sbjct: 1083 TIA---IGVDPLEGKVYWSDSTLHRISRAS----------LDGSQHEDII--TTGLQTTD 1127
Query: 6619 SLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWAD 6798
LA+D I +Y+ D IEV LDG+ RK+L+ ++P +I + ++YW D
Sbjct: 1128 GLAVDAIGRKVYWT--DTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTD 1185
Query: 6799 QGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTP 6978
G+ ++RS +DGS R V++++ + P L VD S + W+DA + I G
Sbjct: 1186 WGENAKLERSGMDGSDRTVLINNNLGWPNGLTVDKTSSQLLWADAHTERIEVADLNGANR 1245
Query: 6979 ELVRSDIASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVA 7158
+ S + G+ L +YWTD + + RA +L V ++L + D+
Sbjct: 1246 HTLVSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKSTGSNVIL-----VRSNLPGLMDIQ 1300
Query: 7159 VFSSNNQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCARGV-LK--GRTCE-EPD 7326
QP + C R C+ LC P +C+C G+ LK G+TC+ P+
Sbjct: 1301 AV-DRAQPLGFNKC----GSRNGGCSHLCLPRPSGF--SCACPTGIQLKGDGKTCDPSPE 1353
Query: 7327 TYIMFSDGDKIIDVAIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNI 7506
TY++FS I ++++ D + P P ++N+ + D D +VY+ + V +++
Sbjct: 1354 TYLLFSSRGSIRRISLDTDDHTD--VHVPVPGLNNVISLDYDSVDGKVYY---TDVFLDV 1408
Query: 7507 SWFSMNNAENPRLVFGASKQPHAKEIRHISDMKLDWLTQKIYFT-TGRGG-KVMAIDTAG 7680
+ N N V G ++ + +DW+ + +Y+T TGR + +D +
Sbjct: 1409 IRRADLNGSNMETVIGHG-------LKTTDGLAVDWVARNLYWTDTGRNTIEASRLDGSC 1461
Query: 7681 EHLSTIASGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESI 7860
+ S D A+A+ P G LFW+D G+ +IER+NL G RKV+++ +
Sbjct: 1462 RKVLINNSLDEPRAIAVFPRKGYLFWTDWGHIA-------KIERANLDGSERKVLINADL 1514
Query: 7861 SLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGY-RAKSLDIWDRWLYMSDP 8037
P + +D+ ++IYW D + IE AD +G+ R+V+ S +L DRW+Y +D
Sbjct: 1515 GWPNGLTLDYDTRRIYWVDAHLDRIESADLNGKLRQVLVSHVSHPFALTQQDRWIYWTDW 1574
Query: 8038 LSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGC 8217
+ + R+DK SG E V+++ + G + + +T C +NGGC
Sbjct: 1575 QTKSIQRVDKYSGRNKETVLAN--VEGLMDIIVVSPQRQTGTNACG--------VNNGGC 1624
Query: 8218 DQLCTVVADDIGLAASKVQCSCND 8289
LC A D C+C D
Sbjct: 1625 SHLCFARASDF-------VCACPD 1641
Score = 473 bits (1216), Expect = e-131
Identities = 324/1036 (31%), Positives = 483/1036 (46%), Gaps = 57/1036 (5%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDT-----YTWH-- 315
C+ DF C++GKCIR W P C+ D++ C WH
Sbjct: 71 CSPLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPCQNGYCIRSLWHCD 130
Query: 316 --------------------------SVSCIAEYQRCDNITDCADGSDEKDCPASTVD-- 411
SCIAE+ CD TDC DGSDE+ CP++
Sbjct: 131 GDNDCGDNSDEQCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEESCPSAVPSPP 190
Query: 412 CSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQ 591
C+ + F CA GR+ D+ CDG DC D SDE D CS +H C +F C D C+
Sbjct: 191 CNLEE-FQCAYGRRILDIYH-CDGDDDCGDWSDESD-CS-SHQPCRSGEFMC-DSGLCVN 245
Query: 592 KSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDEC 771
W CDG DC D SDE + C CTA +F+C++ RC +RCD DDC DNSDE+ C
Sbjct: 246 AGWRCDGDADCDDQSDERN-CTTSMCTAEQFRCRSGRCVRLSWRCDGEDDCADNSDEENC 304
Query: 772 ---GEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLG-------- 918
G +C ++ C G CI Q KLC+G DC D +DE QN P G
Sbjct: 305 ENTGSPQCASDQFLC-WNGRCIGQRKLCNGVNDCGDNSDESP-QQNCRPRTGEENCNVNN 362
Query: 919 --CQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCL 1092
C C +CTC +GY+L + RTC D+NECAE GYC Q C N F C C
Sbjct: 363 GGCAQKCQMIRGAVQCTCHTGYRLTED-GRTCQDVNECAEEGYCSQGCTNSEGAFQCRCE 421
Query: 1093 GDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKLASGE 1272
E P + N C + + + LF A R + ++ P E L + E
Sbjct: 422 AG-----YELRPDRRN------CKALGPEPVLLF-ANRIDIRQVLPHR-SEYTLLLNNLE 468
Query: 1273 FIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNT 1452
+DF + +FW+D A+++ S ++++ L P LAVDW+ +
Sbjct: 469 NAIALDFHHRRELVFWSDVTLDRILRANLNG----SNVEEVVSTGLESPGGLAVDWVHDK 524
Query: 1453 LYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFT---NQLKLEAAAM 1623
LY +SG+ RI+V++ DG R VLL L P IAL P+ G +++T N ++EA++M
Sbjct: 525 LYWTDSGTSRIEVANLDGAHRKVLLWQSLEKPRAIALHPMEGTIYWTDWGNTPRIEASSM 584
Query: 1624 DGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRR-IVAQGMNVVP 1800
DG+ RR + +TH +G+ +D +R+YWVD K +E + G+ R+ +++QG+ P
Sbjct: 585 DGSGRRIIADTHLFWPNGLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVISQGL---P 641
Query: 1801 HPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPG 1980
HPF + +F+ LYWTDW + KF + + N + FPM I HP QP G
Sbjct: 642 HPFAITVFEDSLYWTDWHTKSINSANKFTGKNQEIIRNKLH--FPMDIHTLHPQRQPA-G 698
Query: 1981 QSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGKRCIDSID-YLL 2157
++ C N C +C+ S G Y CACP G + +N C S+D +LL
Sbjct: 699 KNRC-------GDNNGGCTHLCLPS------GQNYTCACPTGFRKINSHACAQSLDKFLL 745
Query: 2158 FSSNKIVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIY 2337
F+ +R I + + L++ V+P++ + ++ D + ++ D+ +TI
Sbjct: 746 FARRMDIRRI--SFDTEDLSDDVIPLADVRSA-----VALDWDSRDDHVYWTDVSTDTIS 798
Query: 2338 RIRPDGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVR 2517
R + DG G V+ T + ++ DW++ +LY+ D + +EV + D +R
Sbjct: 799 RAKWDGTGQKVVVDTSLESPAGLAIDWVTNKLYWTDAGTDRIEV--------ANTDGSMR 850
Query: 2518 RQLITELRD-PVSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAI 2694
LI E D P +VV P G +++ + I R +D N QVI ++ L P+ +AI
Sbjct: 851 TVLIWENLDRPRDIVVEPMGGYMYWTDWGASPKIERAGMDASNRQVIISSNLTWPNGLAI 910
Query: 2695 DFAENRLCWGDTLLKTISCMDFDG-KNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRR 2871
D+ RL W D +KTI DG K V + P P +T+ + IY+ + SI+
Sbjct: 911 DYGSQRLYWADAGMKTIEFAGLDGSKRKVLIGSQLPHPFGLTLYGQRIYWTDWQTKSIQS 970
Query: 2872 VHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQ--CTQLCFATPS 3045
+ G + ++E + ++ + Q P+ PC C+ LC +PS
Sbjct: 971 ADRLTGLDRETLQE---NLENLMDIHVFHRQRPPVTT-----PCAVENGGCSHLCLRSPS 1022
Query: 3046 ESHPNELEAKCACRQG 3093
S C C G
Sbjct: 1023 PS-----GFSCTCPTG 1033
Score = 454 bits (1167), Expect = e-125
Identities = 268/769 (34%), Positives = 387/769 (49%), Gaps = 13/769 (1%)
Frame = +1
Query: 8575 CGDGS-DELDCPSAVACAEGTFPCSNGH-----CINQTKVCDGHNDCHDEQVSDESLATC 8736
C G+ L+C AC F C+ CI CDG NDC D SDE T
Sbjct: 15 CAHGTASNLEC----ACGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDH--SDEDGCTL 68
Query: 8737 PGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGR 8916
P C + C N CI+ + +CDG +DC D +DE C ++C + C +G
Sbjct: 69 P----TCSPLDFHCDNGK-CIRRSWVCDGDNDCEDDSDEQD--CPPRECEEDEFPCQNGY 121
Query: 8917 CIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXX 9096
CI W CDGDNDC D DE + C D F+C + CI+ +
Sbjct: 122 CIRSLWHCDGDNDCGDNSDEQ-------CDMRKC-SDKEFRCSDGSCIAEHWYCDGDTDC 173
Query: 9097 XXXXXXHS-RHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTE 9273
S + C +EF C ++ + CDGD C DES
Sbjct: 174 KDGSDEESCPSAVPSPPCNLEEFQCAYGRRILD--------IYHCDGDDDCGDWSDESD- 224
Query: 9274 LCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCANHK 9453
C + + C GEF C + C+++ W CDGD DC D SDE NCT S C + F+C + +
Sbjct: 225 -CSSHQP-CRSGEFMCDSGLCVNAGWRCDGDADCDDQSDER-NCTTSMCTAEQFRCRSGR 281
Query: 9454 CVPNSWKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFD 9633
CV SW+CDG DDC D SDE++C +N+ S Q C++ QF C +G CI K+C+ D
Sbjct: 282 CVRLSWRCDGEDDCADNSDEENC-ENTGSPQ----CASDQFLCWNGRCIGQRKLCNGVND 336
Query: 9634 CTDRSDESSLCFI------DECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCH 9795
C D SDES + C++ C QKC ++ +C C G+ + D ++C
Sbjct: 337 CGDNSDESPQQNCRPRTGEENCNVNNGG-CAQKCQMIRGAVQCTCHTGYRLT-EDGRTCQ 394
Query: 9796 NVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIR 9975
+VNEC E CSQ C + G+++C C GY+L D +CK + PEP L AN+ IR
Sbjct: 395 DVNECAEE-GYCSQGCTNSEGAFQCRCEAGYELRPDRRNCKA--LGPEPVLLFANRIDIR 451
Query: 9976 KISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVL 10155
++ ++Y L +N ++LD + + D R+LR +L+ S+ E V+
Sbjct: 452 QVLPHRSEYTLLLNNLENAIALDFHHRRELVFWSDVTLDRILRANLNG-----SNVEEVV 506
Query: 10156 RHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKG 10335
+ G+AVDWV KLY + I V LDG K L+ +++P+AI +HP +G
Sbjct: 507 STGLESPGGLAVDWVHDKLYWTDSGTSRIEVANLDGAHRKVLLWQSLEKPRAIALHPMEG 566
Query: 10336 YLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNE 10515
+++T+W P I ++DGS +A+ L WPN + IDY R++W DA +
Sbjct: 567 TIYWTDWGNTPRIEASSMDGSGRRI-----IADTHLFWPNGLTIDYAGRRMYWVDAKHHV 621
Query: 10516 IGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTV 10695
I + DG+ R+ + +Q H ++ VF+D LYW DW+ + + +K+TGKN+ I++ +
Sbjct: 622 IERANLDGSHRKAVISQGLPHPFAITVFEDSLYWTDWHTKSINSANKFTGKNQEIIRNKL 681
Query: 10696 QLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQF 10842
P D+ +HP RQPA N CGDNNGGC+HLCL G YTC+CP F
Sbjct: 682 HFPMDIHTLHPQRQPAGKNRCGDNNGGCTHLCL--PSGQNYTCACPTGF 728
Score = 387 bits (993), Expect = e-105
Identities = 273/1015 (26%), Positives = 481/1015 (46%), Gaps = 8/1015 (0%)
Frame = +1
Query: 4312 ENECLDSSS-CSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRN--RI 4482
+N C D++ C+ C +TC+C G+ ++ C A ++ ++ + RI
Sbjct: 699 KNRCGDNNGGCTHLCLPSGQNYTCACPTGFR-KINSHAC--AQSLDKFLLFARRMDIRRI 755
Query: 4483 YYSDHKLDNWHTFGAIVENAIALAWDSLTDRIYWSDIREKKILSANRNGTNATVFIADGL 4662
+ L + A V +A+AL WDS D +YW+D+ I A +GT V + L
Sbjct: 756 SFDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDGTGQKVVVDTSL 815
Query: 4663 DITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMF 4842
+ G+A+DWV LYW D+ + IEVAN D RT+L+ +N+ +PR I V+P G M+
Sbjct: 816 ESPAGLAIDWVTNKLYWTDAGTDRIEVANT-DGSMRTVLIWENLDRPRDIVVEPMGGYMY 874
Query: 4843 WTDWGQNPCIERASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDG 5022
WTDWG +P IERA MD ++RQ+I+ + + WPN +A+DY + R+Y+AD+ + I+F DG
Sbjct: 875 WTDWGASPKIERAGMDASNRQVIISSNLTWPNGLAIDYGSQRLYWADAGMKTIEFAGLDG 934
Query: 5023 SGRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALG 5202
S R ++ S + HP L ++ +Y++D + + +Q + G E +
Sbjct: 935 SKRKVLIGSQ--LPHPFGLTLYGQRIYWTDWQTKSIQSADRL-TGLDRETLQENLENLMD 991
Query: 5203 VVAVHPVLQPVIKNNPCSTNPCSHLCLLN-NKNTFTCKCPMGEKLDASGKKCIDDAKPFL 5379
+ H PV CSHLCL + + + F+C CP G L GK C FL
Sbjct: 992 IHVFHRQRPPVTTPCAVENGGCSHLCLRSPSPSGFSCTCPTGINLLLDGKTCSPGMNSFL 1051
Query: 5380 VIIQKTNVFGIEMNSASEKETPVLAG-MVPLS-GLGNAFDAAYDALSEEMFILEHTNHAK 5553
+ ++ +V + + + P A +VP++ + N D L +++ + T H
Sbjct: 1052 IFARRIDVRMVSL------DIPYFADVVVPINMTMKNTIAIGVDPLEGKVYWSDSTLH-- 1103
Query: 5554 TLAQITTDSAIYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRT 5733
+++ + D + + + G +T L D GR + + T IE+
Sbjct: 1104 RISRASLDGSQHEDIITTGLQT----------TDGLAVDAIGRKVYWTDTGTNRIEVGNL 1153
Query: 5734 QGKQYRSVILSNDQSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLV 5913
G + ++ N S G+++W D G +AK+ R+G+DGS+ V
Sbjct: 1154 DGSMRKVLVWQNLDS------PRAIVLYHEMGFMYWTDWG---ENAKLERSGMDGSDRTV 1204
Query: 5914 IASNDLAELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGD 6093
+ +N+L + + +D T++++ +++A RI +G +RH ++S + P GL
Sbjct: 1205 LINNNLGWPNGLTVDKTSSQLLWADAHTERIEVADLNGANRHTLVSP-VQHPYGLTLLDS 1263
Query: 6094 RLFYADSAFDSIEVATINGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHINNGNC 6273
+++ D SI A + S + ++ L +I+A+ + C NG C
Sbjct: 1264 YIYWTDWQTRSIHRADKSTGSNV---ILVRSNLPGLMDIQAVDRAQPLGFNKCGSRNGGC 1320
Query: 6274 DHICIPLMFAQRTCTCANG-YVKDGQTSCKLFDESFVIVATKTKVIGYPIDETQSKGVAM 6450
H+C+P + +C C G +K +C E++++ +++ + +D V +
Sbjct: 1321 SHLCLPRP-SGFSCACPTGIQLKGDGKTCDPSPETYLLFSSRGSIRRISLDTDDHTDVHV 1379
Query: 6451 EPIGGL-SITGVDYDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIKSLA 6627
P+ GL ++ +DYD +Y + I + S+ VI G T LA
Sbjct: 1380 -PVPGLNNVISLDYDSVDGKVYYTDV--FLDVIRRADLNGSNMETVI--GHGLKTTDGLA 1434
Query: 6628 IDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQ 6807
+DW+ N+Y+ D R IE S+LDG+ RK+L+ + P +IAV P YL+W D G
Sbjct: 1435 VDWVARNLYWT--DTGRNTIEASRLDGSCRKVLINNSLDEPRAIAVFPRKGYLFWTDWGH 1492
Query: 6808 KPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPELV 6987
I+R+ LDGS R+V++++ + P L +D ++ IYW DA +D I G +++
Sbjct: 1493 IAKIERANLDGSERKVLINADLGWPNGLTLDYDTRRIYWVDAHLDRIESADLNGKLRQVL 1552
Query: 6988 RSDIASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFS 7167
S ++ + + +YWTD + + + R + + TV A+++ + D+ V S
Sbjct: 1553 VSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGR-----NKETVLANVEGLMDIIVVS 1607
Query: 7168 SNNQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCARGVLKGRTCEEPDTY 7332
Q ++ C + + C+ LCFA C+C +EPD++
Sbjct: 1608 PQRQ-TGTNACGVNN----GGCSHLCFAR--ASDFVCACP---------DEPDSH 1646
Score = 326 bits (836), Expect = 9e-87
Identities = 231/779 (29%), Positives = 339/779 (42%), Gaps = 50/779 (6%)
Frame = +1
Query: 11359 ECAQIECKKGWTRCSSSY----RCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCA 11526
ECA C + C+ S CIP C+G +DC D+SDED PTC + +F C
Sbjct: 24 ECA---CGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDEDGCTLPTCSPL-DFHC- 78
Query: 11527 TSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQ 11706
+GKCI R W+CD +NDC D+SDE D R C E EF C +G CI CDG
Sbjct: 79 DNGKCIRRSWVCDGDNDCEDDSDEQDCP----PRECEEDEFPCQNGYCIRSLWHCDGDND 134
Query: 11707 CSDGLDESQCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCEDV-------- 11862
C D DE QC +R+C +C DG+CIAEH +CD DC + +DE C
Sbjct: 135 CGDNSDE-QCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEESCPSAVPSPPCNL 193
Query: 11863 ---------------------------------SRRTCSPFEFECANSVCIPRKFMXXXX 11943
S + C EF C + +C+ +
Sbjct: 194 EEFQCAYGRRILDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMCDSGLCVNAGWRCDGD 253
Query: 11944 XXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCS 12123
SDE + C ++ C +FRC R C+ + C+G +DC N SDE C
Sbjct: 254 ADCDDQSDERN--CTTSMCTAE-QFRCRSGR-CVRLSWRCDGEDDCADN--SDEE--NCE 305
Query: 12124 SFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEI---GCSKHGGKTSCEAFGNN 12294
+ C+SDQF C NG+C+ C+ +DCGD SDE C G+ +C NN
Sbjct: 306 NTGS-PQCASDQFLCWNGRCIGQRKLCNGVNDCGDNSDESPQQNCRPRTGEENCNV--NN 362
Query: 12295 GGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGSYLCRCH 12474
GGC C +R C C G+R + + C D++ECA C+Q C N++G++ CRC
Sbjct: 363 GGCAQKCQMIRGAVQCTCHTGYRLT-EDGRTCQDVNECAEEGYCSQGCTNSEGAFQCRCE 421
Query: 12475 EDYENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXX 12654
YE ++C+A G ++ + Q+ H R
Sbjct: 422 AGYELR-----PDRRNCKALGPEPVLLFANRIDIRQVLPH-----RSEYTLLLNNLENAI 471
Query: 12655 XXXXXPRKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTAIAVDYTTGN 12834
R+EL++W S+ T+ R AN N S+ + + + P +AVD+
Sbjct: 472 ALDFHHRRELVFW---SDVTLDRILRANLNGSNVEEVVSTGLES----PGGLAVDWVHDK 524
Query: 12835 LFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALIT 13014
L+ + T I V DG + K ++ L++P A+
Sbjct: 525 LYWT-----------------------DSGTSRIEVANLDGAHRKVLLWQSLEKPRAIAL 561
Query: 13015 APSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYR 13194
P G I ++D G +IE + MDG+ R+II +F P + ID G R+YWVD K+
Sbjct: 562 HPMEGTIYWTDWGNTPRIEASSMDGSGRRIIADTHLFWPNGLTIDYA-GRRMYWVDAKHH 620
Query: 13195 RVDAVNIDGSERTTVV-HDRHIPYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASD 13371
++ N+DGS R V+ P+A+ VFE+ +YW +K++ +KF ++ +
Sbjct: 621 VIERANLDGSHRKAVISQGLPHPFAITVFEDSLYWTDWHTKSINSANKFTGKNQEIIRNK 680
Query: 13372 LEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPS-TGFACLCPDGIVPQLDGSCA 13545
L + + + G C+HLC LPS + C CP G +CA
Sbjct: 681 LHFPMDIHTLHPQRQPAGKNRCGDNNGGCTHLC--LPSGQNYTCACPTGFRKINSHACA 737
Score = 248 bits (633), Expect = 3e-63
Identities = 198/732 (27%), Positives = 333/732 (45%), Gaps = 12/732 (1%)
Frame = +1
Query: 1018 NECAEF-GYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLF 1194
N C + G C LC +TC+C G K N + + + DK LF
Sbjct: 700 NRCGDNNGGCTHLCLPSGQNYTCAC---------PTGFRKIN----SHACAQSLDKFLLF 746
Query: 1195 VARREGLYRLNPKNPD--EEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDE 1368
ARR + R++ D ++V LA +D+D D ++WTD + A D
Sbjct: 747 -ARRMDIRRISFDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDGT 805
Query: 1369 GEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLP 1548
G+ K + SL P LA+DW+TN LY ++G+ RI+V++ DG RTVL+ + L P
Sbjct: 806 GQ----KVVVDTSLESPAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRP 861
Query: 1549 LDIALDPLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVD 1719
DI ++P+ G M++T+ K+E A MD +NR+ +++++ +G+ +D ++R+YW D
Sbjct: 862 RDIVVEPMGGYMYWTDWGASPKIERAGMDASNRQVIISSNLTWPNGLAIDYGSQRLYWAD 921
Query: 1720 PKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKF-GSDT 1896
+ +E G+ R+++ +PHPFGL L+ Q +YWTDW + ++ G D
Sbjct: 922 AGMKTIEFAGLDGSKRKVLIGSQ--LPHPFGLTLYGQRIYWTDWQTKSIQSADRLTGLDR 979
Query: 1897 KLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCT--NADCEGMCILSKDNGG 2070
+ L N EN M I +H P + PC N C +C+ S G
Sbjct: 980 ETLQENLEN---LMDIHVFHRQRPP-----------VTTPCAVENGGCSHLCLRSPSPSG 1025
Query: 2071 FGVGYKCACPIG-QKLVNGKRCIDSID-YLLFSSNKIVRGIFPEINEKALAEAVLPISPI 2244
F C CP G L++GK C ++ +L+F+ VR + +I A+ V+PI+
Sbjct: 1026 F----SCTCPTGINLLLDGKTCSPGMNSFLIFARRIDVRMVSLDI--PYFADVVVPINMT 1079
Query: 2245 SQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWIS 2424
+ I + D +++D + I R DG ++ T ++ D I
Sbjct: 1080 MKNTIA----IGVDPLEGKVYWSDSTLHRISRASLDGSQHEDIITTGLQTTDGLAVDAIG 1135
Query: 2425 KQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITE-LRDPVSVVVHPWKGLLFYAEAM 2601
+++Y+ D N +EV + D +R+ L+ + L P ++V++ G +++ +
Sbjct: 1136 RKVYWTDTGTNRIEVGNL--------DGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTDWG 1187
Query: 2602 RPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVK 2781
A + R +DG + V+ N LG P+ + +D ++L W D + I D +G N
Sbjct: 1188 ENAKLERSGMDGSDRTVLINNNLGWPNGLTVDKTSSQLLWADAHTERIEVADLNGANRHT 1247
Query: 2782 LDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSH 2961
L P +T+++ YIY+ + SI R K G +VR ++ L
Sbjct: 1248 LVSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKSTGSNVILVRS------NLPGLMDIQA 1301
Query: 2962 QNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINKENNHSCQKDPA 3141
++ P + R C+ LC PS CAC G + K + +C DP+
Sbjct: 1302 VDRAQPLGFNKCGSRNGGCSHLCLPRPS-------GFSCACPTGIQL-KGDGKTC--DPS 1351
Query: 3142 EKIEQLCSSNST 3177
+ L SS +
Sbjct: 1352 PETYLLFSSRGS 1363
Score = 233 bits (593), Expect = 1e-58
Identities = 128/349 (36%), Positives = 186/349 (52%), Gaps = 3/349 (0%)
Frame = +1
Query: 9802 NECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKI 9981
N+C GCS C + + C C G QL D +C + PE + L +++ IR+I
Sbjct: 1311 NKCGSRNGGCSHLCLPRPSGFSCACPTGIQLKGDGKTC---DPSPETYLLFSSRGSIRRI 1367
Query: 9982 SIDGNKY---ELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETV 10152
S+D + + + G +NV+SLD D + K Y D + R DL+ S+ ETV
Sbjct: 1368 SLDTDDHTDVHVPVPGLNNVISLDYDSVDGKVYYTDVFLDVIRRADLNG-----SNMETV 1422
Query: 10153 LRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGK 10332
+ H + T+G+AVDWV R LY + +I LDG K LI + + +P+AI V P K
Sbjct: 1423 IGHGLKTTDGLAVDWVARNLYWTDTGRNTIEASRLDGSCRKVLINNSLDEPRAIAVFPRK 1482
Query: 10333 GYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLN 10512
GYLF+T+W I R LDGS L DLGWPN + +DY + R++W DAHL+
Sbjct: 1483 GYLFWTDWGHIAKIERANLDGSERK-----VLINADLGWPNGLTLDYDTRRIYWVDAHLD 1537
Query: 10513 EIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKT 10692
I D +G R + SH ++ D ++YW DW + + R DK++G+N+ +
Sbjct: 1538 RIESADLNGK-LRQVLVSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVLAN 1596
Query: 10693 VQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQ 10839
V+ D+ +V P RQ N CG NNGGCSHLC A + + C+CPD+
Sbjct: 1597 VEGLMDIIVVSPQRQTG-TNACGVNNGGCSHLCF--ARASDFVCACPDE 1642
Score = 223 bits (569), Expect = 8e-56
Identities = 203/734 (27%), Positives = 325/734 (43%), Gaps = 19/734 (2%)
Frame = +1
Query: 994 FHRTCSDINE-CA-EFGYCDQLCANHRP--GFTCSCLGDCFTLQMEHGPGKDNLTMRGYC 1161
FHR + CA E G C LC GF+C+C P NL + G
Sbjct: 995 FHRQRPPVTTPCAVENGGCSHLCLRSPSPSGFSCTC------------PTGINLLLDGKT 1042
Query: 1162 VSNNADKMKLFVARREGLYRLN---PKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRL 1332
S + +F ARR + ++ P D V + + I D + K++W+D
Sbjct: 1043 CSPGMNSFLIF-ARRIDVRMVSLDIPYFADVVVPINMTMKNTIAIGVDPLEGKVYWSDST 1101
Query: 1333 AHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGER 1512
H A +D SQ + + L LAVD I +Y ++G+ RI+V + DG
Sbjct: 1102 LHRISRASLDG----SQHEDIITTGLQTTDGLAVDAIGRKVYWTDTGTNRIEVGNLDGSM 1157
Query: 1513 RTVLLADGLTLPLDIALDPLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHTHQVSGIV 1683
R VL+ L P I L G M++T+ KLE + MDG++R L+N + +G+
Sbjct: 1158 RKVLVWQNLDSPRAIVLYHEMGFMYWTDWGENAKLERSGMDGSDRTVLINNNLGWPNGLT 1217
Query: 1684 VDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLG 1863
VD T+ ++ W D +R+E D G +R + ++ V HP+GL L D Y+YWTDW
Sbjct: 1218 VDKTSSQLLWADAHTERIEVADLNGANRHTL---VSPVQHPYGLTLLDSYIYWTDWQTRS 1274
Query: 1864 VIQVEKF-GSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEG 2040
+ + +K GS+ L+ SN + + P+ G ++C + N C
Sbjct: 1275 IHRADKSTGSNVILVRSNLPGLMDIQAVDRAQPL-----GFNKCGSR-------NGGCSH 1322
Query: 2041 MCILSKDNGGFGVGYKCACPIGQKLV-NGKRCIDSID-YLLFSSNKIVRGIFPEINEKAL 2214
+C+ G+ CACP G +L +GK C S + YLLFSS +R I + ++
Sbjct: 1323 LCLPRPS------GFSCACPTGIQLKGDGKTCDPSPETYLLFSSRGSIRRISLDTDDHTD 1376
Query: 2215 AEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVL---VTH 2385
+P + ++ D +Y D+ + I R +G V+ +
Sbjct: 1377 VHVPVP-------GLNNVISLDYDSVDGKVYYTDVFLDVIRRADLNGSNMETVIGHGLKT 1429
Query: 2386 NDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITE-LRDPVSVVV 2562
DGL + DW+++ LY+ D RN++E ++ D R+ LI L +P ++ V
Sbjct: 1430 TDGL---AVDWVARNLYWTDTGRNTIEASRL--------DGSCRKVLINNSLDEPRAIAV 1478
Query: 2563 HPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKT 2742
P KG LF+ + A I R ++DG +V+ N LG P+ + +D+ R+ W D L
Sbjct: 1479 FPRKGYLFWTDWGHIAKIERANLDGSERKVLINADLGWPNGLTLDYDTRRIYWVDAHLDR 1538
Query: 2743 ISCMDFDGKNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGA 2922
I D +GK L P A+T + +IY+ + SI+RV K +G + V A
Sbjct: 1539 IESADLNGKLRQVLVSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVL---A 1595
Query: 2923 DERSIFSLKACSHQNQPIPDDSREHPCRASQ--CTQLCFATPSESHPNELEAKCACRQGF 3096
+ + + S Q Q + + C + C+ LCFA S + CAC
Sbjct: 1596 NVEGLMDIIVVSPQRQ-----TGTNACGVNNGGCSHLCFARAS-------DFVCACP--- 1640
Query: 3097 MINKENNHSCQKDP 3138
++ ++H C P
Sbjct: 1641 --DEPDSHPCSLVP 1652
Score = 195 bits (496), Expect = 2e-47
Identities = 110/361 (30%), Positives = 171/361 (46%), Gaps = 3/361 (0%)
Frame = +1
Query: 9802 NECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKI 9981
N C + GC+ C +Y C C G++ + H+C ++ + F L A + IR+I
Sbjct: 700 NRCGDNNGGCTHLCLPSGQNYTCACPTGFR-KINSHACAQSL---DKFLLFARRMDIRRI 755
Query: 9982 SIDGNKYE---LAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETV 10152
S D + + V+LD D + Y D + R D + + V
Sbjct: 756 SFDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDG-----TGQKVV 810
Query: 10153 LRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGK 10332
+ ++ G+A+DWV KLY + I V DG LI + + +P+ IVV P
Sbjct: 811 VDTSLESPAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRPRDIVVEPMG 870
Query: 10333 GYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLN 10512
GY+++T+W P I R +D S + +L WPN +AIDY S RL+W DA +
Sbjct: 871 GYMYWTDWGASPKIERAGMDASNRQV-----IISSNLTWPNGLAIDYGSQRLYWADAGMK 925
Query: 10513 EIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKT 10692
I F DG+ R+ + + H + ++ +YW DW + + D+ TG + L++
Sbjct: 926 TIEFAGLDGSKRKVLIGSQLPHPFGLTLYGQRIYWTDWQTKSIQSADRLTGLDRETLQEN 985
Query: 10693 VQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTCE 10872
++ D+ + H R P PC NGGCSHLCL +G++C+CP LL D KTC
Sbjct: 986 LENLMDIHVFHRQRPPV-TTPCAVENGGCSHLCLRSPSPSGFSCTCPTGINLLLDGKTCS 1044
Query: 10873 P 10875
P
Sbjct: 1045 P 1045
Score = 191 bits (486), Expect = 3e-46
Identities = 112/357 (31%), Positives = 169/357 (46%), Gaps = 6/357 (1%)
Frame = +1
Query: 9826 GCSQKC--DDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNK 9999
GCS C + C C G L D +C F + A + +R +S+D
Sbjct: 1012 GCSHLCLRSPSPSGFSCTCPTGINLLLDGKTCSPGM---NSFLIFARRIDVRMVSLDIPY 1068
Query: 10000 YELAAQGFD----NVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNV 10167
+ + N +++ +D E K Y D R+ R LD S +E ++ +
Sbjct: 1069 FADVVVPINMTMKNTIAIGVDPLEGKVYWSDSTLHRISRASLDG-----SQHEDIITTGL 1123
Query: 10168 YGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFF 10347
T+G+AVD +GRK+Y + I V LDG K L+ + P+AIV++ G++++
Sbjct: 1124 QTTDGLAVDAIGRKVYWTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYW 1183
Query: 10348 TEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFM 10527
T+W + R +DGS L ++LGWPN + +D S +L W DAH I
Sbjct: 1184 TDWGENAKLERSGMDGSDRT-----VLINNNLGWPNGLTVDKTSSQLLWADAHTERIEVA 1238
Query: 10528 DFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPN 10707
D +G RH H + + D Y+YW DW R + R DK TG N +++ +
Sbjct: 1239 DLNG-ANRHTLVSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKSTGSNVILVRSNLPGLM 1297
Query: 10708 DLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTCEPN 10878
D++ V QP N CG NGGCSHLCL +G++C+CP L D KTC+P+
Sbjct: 1298 DIQAV-DRAQPLGFNKCGSRNGGCSHLCL--PRPSGFSCACPTGIQLKGDGKTCDPS 1351
Score = 155 bits (392), Expect = 3e-35
Identities = 115/387 (29%), Positives = 160/387 (40%), Gaps = 22/387 (5%)
Frame = +1
Query: 8383 PYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCN 8562
P +F C +G CI CD DC D SDE C R C ED C N CI S C+
Sbjct: 73 PLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQD--CPPRECEEDEFPCQNGYCIRSLWHCD 130
Query: 8563 HIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPG 8742
+DCGD SDE C C++ F CS+G CI + CDG DC D + + P
Sbjct: 131 GDNDCGDNSDE-QCDMR-KCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEESCPSAVPS 188
Query: 8743 LPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCI 8922
P C + +C + CDG DDCGD +DE+ +Q C C SG C+
Sbjct: 189 PP--CNLEEFQCAYGRRILDIYH-CDGDDDCGDWSDESDC-SSHQPCRSGEFMCDSGLCV 244
Query: 8923 PETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXX 9102
W+CDGD DC D DE NCT + +C + F+C + +C+ ++
Sbjct: 245 NAGWRCDGDADCDDQSDE--RNCTTS----MCTAEQ-FRCRSGRCVRLSWRCDGEDDCAD 297
Query: 9103 XXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTEL-C 9279
+ G+ C +F C + CI + LC+G C DES + C
Sbjct: 298 NSDEENCENTGSPQCASDQFLCWNG--------RCIGQRKLCNGVNDCGDNSDESPQQNC 349
Query: 9280 --KTEKKECNKGEFRCSN---------QHCIHSTWE-------CDGDNDCLDGSDEHANC 9405
+T ++ CN C+ Q H+ + C N+C + C
Sbjct: 350 RPRTGEENCNVNNGGCAQKCQMIRGAVQCTCHTGYRLTEDGRTCQDVNECAEEGYCSQGC 409
Query: 9406 TYSSCQPDFFQC---ANHKCVPNSWKC 9477
T S FQC A ++ P+ C
Sbjct: 410 TNSE---GAFQCRCEAGYELRPDRRNC 433
Score = 144 bits (364), Expect = 5e-32
Identities = 102/329 (31%), Positives = 142/329 (43%), Gaps = 9/329 (2%)
Frame = +1
Query: 8362 PAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCI 8541
P +EC F C +G CI CD DC D SDE C+ R C + C++ CI
Sbjct: 106 PPRECEED-EFPCQNGYCIRSLWHCDGDNDCGDNSDEQ---CDMRKCSDKEFRCSDGSCI 161
Query: 8542 DSAKKCNHIDDCGDGSDELDCPSAV---ACAEGTFPCSNGHCINQTKVCDGHNDCHDEQV 8712
C+ DC DGSDE CPSAV C F C+ G I CDG +DC D
Sbjct: 162 AEHWYCDGDTDCKDGSDEESCPSAVPSPPCNLEEFQCAYGRRILDIYHCDGDDDCGD--W 219
Query: 8713 SDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQH 8892
SDES + CR + C ++ +C+ CDG DC D++DE C C
Sbjct: 220 SDESDCSSHQ---PCRSGEFMC-DSGLCVNAGWRCDGDADCDDQSDERN--CTTSMCTAE 273
Query: 8893 YVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAF 9072
RC SGRC+ +W+CDG++DC+D DE NC +T G C D F C N +CI +
Sbjct: 274 QFRCRSGRCVRLSWRCDGEDDCADNSDE--ENCENT-GSPQCASDQ-FLCWNGRCIGQRK 329
Query: 9073 IXXXXXXXXXXXXXHSRHGC----GNRTCTDQEFHCTSNAKLAQPKYECIPRAW--LCDG 9234
+ + C G C C ++ + +C L +
Sbjct: 330 LCNGVNDCGDNSDESPQQNCRPRTGEENCNVNNGGCAQKCQMIRGAVQCTCHTGYRLTED 389
Query: 9235 DVTCAGGEDESTELCKTEKKECNKGEFRC 9321
TC + + E ++ ++G F+C
Sbjct: 390 GRTCQDVNECAEEGYCSQGCTNSEGAFQC 418
Score = 126 bits (317), Expect = 1e-26
Identities = 99/313 (31%), Positives = 127/313 (39%), Gaps = 7/313 (2%)
Frame = +1
Query: 11590 SDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQ 11769
+ L+ +CG + C+ S + CIP CDG C D DE CTL C P
Sbjct: 20 ASNLECACGRSHFTCAVSAL--GECTCIPAQWQCDGDNDCGDHSDEDGCTLPTCSPLDFH 77
Query: 11770 CDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFECANSVCIPRKFMXXXXXX 11949
CD+G CI CD DC + +DE C R C EF C N CI +
Sbjct: 78 CDNGKCIRRSWVCDGDNDCEDDSDEQDCPP---RECEEDEFPCQNGYCIRSLWHCDGDND 134
Query: 11950 XXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSF 12129
SDE +C +C FRC+ C+ C+G DC D SDE C S
Sbjct: 135 CGDNSDE---QCDMRKCSDK-EFRCSDGS-CIAEHWYCDGDTDC--KDGSDEE--SCPSA 185
Query: 12130 SEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKH 12309
C+ ++F+CA G+ + CD DDCGD SDE CS H S E ++G C
Sbjct: 186 VPSPPCNLEEFQCAYGRRILDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMCDSGLC-- 243
Query: 12310 ICTDVRDGFYCHCRDGFRP-DPQSPKECIDIDECAG------NNTCTQLCLNTKGSYLCR 12468
V G+ C DG D QS + C + C +L G C
Sbjct: 244 ----VNAGWRC---DGDADCDDQSDERNCTTSMCTAEQFRCRSGRCVRLSWRCDGEDDCA 296
Query: 12469 CHEDYENNVVVGS 12507
+ D EN GS
Sbjct: 297 DNSDEENCENTGS 309
Score = 111 bits (277), Expect = 6e-22
Identities = 80/290 (27%), Positives = 131/290 (44%), Gaps = 2/290 (0%)
Frame = +1
Query: 12673 RKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAV 12852
R + +YW D S TI R+ GQK+ VD + P +A+D+ T L+
Sbjct: 783 RDDHVYWTDVSTDTISRA-----KWDGTGQKVVVDTSLES--PAGLAIDWVTNKLYWT-- 833
Query: 12853 SENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGR 13032
+ T I V DG ++ +L +P ++ P G
Sbjct: 834 ---------------------DAGTDRIEVANTDGSMRTVLIWENLDRPRDIVVEPMGGY 872
Query: 13033 ICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVN 13212
+ ++D G KIE A MD ++RQ+I+ + P +AID G R+YW D + ++
Sbjct: 873 MYWTDWGASPKIERAGMDASNRQVIISSNLTWPNGLAIDYG-SQRLYWADAGMKTIEFAG 931
Query: 13213 IDGSERTTVVHDR-HIPYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHT 13389
+DGS+R ++ + P+ + ++ IYW ++K++ D+ L +LE+
Sbjct: 932 LDGSKRKVLIGSQLPHPFGLTLYGQRIYWTDWQTKSIQSADRLTGLDRETLQENLENLMD 991
Query: 13390 VRVSQKYAKDTQRTVSGCERAQCSHLCVSLPS-TGFACLCPDGIVPQLDG 13536
+ V + + T E CSHLC+ PS +GF+C CP GI LDG
Sbjct: 992 IHVFHR-QRPPVTTPCAVENGGCSHLCLRSPSPSGFSCTCPTGINLLLDG 1040
Score = 104 bits (260), Expect = 6e-20
Identities = 66/213 (30%), Positives = 94/213 (43%), Gaps = 29/213 (13%)
Frame = +1
Query: 520 SCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNK 699
+C R+H C + CI W CDG DC D SDE D C C+ +F C N
Sbjct: 26 ACGRSHFTC---AVSALGECTCIPAQWQCDGDNDCGDHSDE-DGCTLPTCSPLDFHCDNG 81
Query: 700 RCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGAD 879
+C R + CD +DC D+SDE +C C ++ C G+CI L CDG DC D +D
Sbjct: 82 KCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPCQ-NGYCIRSLWHCDGDNDCGDNSD 140
Query: 880 EQ-----------QCSQNLC--------PSLGCQAGCH--------PSP--HGGECTCPS 972
EQ +CS C C+ G PSP + E C
Sbjct: 141 EQCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEESCPSAVPSPPCNLEEFQCAY 200
Query: 973 GYKLDDRFHRTCSDINECAEFGYCDQLCANHRP 1071
G ++ D +H C ++C ++ + C++H+P
Sbjct: 201 GRRILDIYH--CDGDDDCGDWS-DESDCSSHQP 230
Score = 98.6 bits (244), Expect = 4e-18
Identities = 54/195 (27%), Positives = 104/195 (52%)
Frame = +1
Query: 12952 DGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSP 13131
DG K +V +L P A++ G + ++D G +AK+E + MDG+ R +++ + + P
Sbjct: 1154 DGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTDWGENAKLERSGMDGSDRTVLINNNLGWP 1213
Query: 13132 TSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSRES 13311
+ +D+ +++ W D R++ +++G+ R T+V PY + + +++IYW ++
Sbjct: 1214 NGLTVDK-TSSQLLWADAHTERIEVADLNGANRHTLVSPVQHPYGLTLLDSYIYWTDWQT 1272
Query: 13312 KTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTG 13491
++++ DK V ++ S+L ++ + A+ G CSHLC+ PS G
Sbjct: 1273 RSIHRADKSTGSNVILVRSNLPGLMDIQAVDR-AQPLGFNKCGSRNGGCSHLCLPRPS-G 1330
Query: 13492 FACLCPDGIVPQLDG 13536
F+C CP GI + DG
Sbjct: 1331 FSCACPTGIQLKGDG 1345
Score = 94.0 bits (232), Expect = 1e-16
Identities = 57/188 (30%), Positives = 96/188 (50%), Gaps = 1/188 (0%)
Frame = +1
Query: 12952 DGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSP 13131
DG K ++ L +P A+ P G + ++D G AKIE A++DG+ R++++ + P
Sbjct: 1458 DGSCRKVLINNSLDEPRAIAVFPRKGYLFWTDWGHIAKIERANLDGSERKVLINADLGWP 1517
Query: 13132 TSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSRES 13311
+ +D RIYWVD R+++ +++G R +V P+A+ + IYW ++
Sbjct: 1518 NGLTLDYDT-RRIYWVDAHLDRIESADLNGKLRQVLVSHVSHPFALTQQDRWIYWTDWQT 1576
Query: 13312 KTLYVQDKF-GRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPST 13488
K++ DK+ GR + +VLA+ +G + + T G CSHLC + S
Sbjct: 1577 KSIQRVDKYSGRNKETVLAN--VEGLMDIIVVSPQRQTGTNACGVNNGGCSHLCFARAS- 1633
Query: 13489 GFACLCPD 13512
F C CPD
Sbjct: 1634 DFVCACPD 1641
Score = 65.9 bits (159), Expect = 3e-08
Identities = 64/261 (24%), Positives = 90/261 (33%), Gaps = 12/261 (4%)
Frame = +1
Query: 10816 YTCSCPDQFVLLSDQKTCEPN--CTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGE 10989
Y C D SD+ C + C +F C D C+ W CDG+ DC D SDE
Sbjct: 208 YHCDGDDDCGDWSDESDCSSHQPCRSGEFMC--DSGLCVNAGWRCDGDADCDDQSDERN- 264
Query: 10990 SICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXXEQNCDKACDPWMFKCAA----- 11154
C +C +F+C + C R E+NC+ P +CA+
Sbjct: 265 --CTTSMCTAEQFRCRSGRCVRLSWRCDGEDDCADNSDEENCENTGSP---QCASDQFLC 319
Query: 11155 -TGRCIPRRFTXXXXXXXXXRSDEADTLCMSAERNC---TAEE-FRCNNNKCIAKAWRXX 11319
GRCI +R SDE S ++NC T EE NN C K
Sbjct: 320 WNGRCIGQRKLCNGVNDCGDNSDE------SPQQNCRPRTGEENCNVNNGGCAQKCQMIR 373
Query: 11320 XXXXXXXXXXETPECAQIECKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTC 11499
++C C + YR + C ++C + Q C
Sbjct: 374 ---------------GAVQC-----TCHTGYRLTEDGRTCQDVNECAEEG-YCSQGCTNS 412
Query: 11500 DDVGEFRCATSGKCIPRRWMC 11562
+ + RC + P R C
Sbjct: 413 EGAFQCRCEAGYELRPDRRNC 433
Score = 65.9 bits (159), Expect = 3e-08
Identities = 52/202 (25%), Positives = 78/202 (37%), Gaps = 17/202 (8%)
Frame = +1
Query: 139 NTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHS 318
N +S+C FRC G+C+R W
Sbjct: 264 NCTTSMCTAEQFRCRSGRCVRLSW------------------------------------ 287
Query: 319 VSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCR 498
RCD DCAD SDE++C + + + F+C +GR C K C+G DC
Sbjct: 288 --------RCDGEDDCADNSDEENCENTGSPQCASDQFLCWNGR-CIGQRKLCNGVNDCG 338
Query: 499 DLSDE-----------KDSCSRNHTACFQ--YQFRCADKTQCIQKSWVCDGSKDCADGSD 639
D SDE +++C+ N+ C Q R A + C + + + C D ++
Sbjct: 339 DNSDESPQQNCRPRTGEENCNVNNGGCAQKCQMIRGAVQCTCHTGYRLTEDGRTCQDVNE 398
Query: 640 --EPDTCEFKKCTANE--FQCK 693
E C + CT +E FQC+
Sbjct: 399 CAEEGYCS-QGCTNSEGAFQCR 419
Score = 48.5 bits (114), Expect = 0.005
Identities = 29/106 (27%), Positives = 56/106 (52%), Gaps = 3/106 (2%)
Frame = +1
Query: 12988 LQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNR 13167
++ A+ P G++ +SD+ LH +I A +DG+ + I+ + + +A+D G +
Sbjct: 1080 MKNTIAIGVDPLEGKVYWSDSTLH-RISRASLDGSQHEDIITTGLQTTDGLAVD-AIGRK 1137
Query: 13168 IYWVDPKYRRVDAVNIDGSERTTVV-HDRHIPYAVDVFE--NHIYW 13296
+YW D R++ N+DGS R +V + P A+ ++ +YW
Sbjct: 1138 VYWTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYW 1183
Score = 38.9 bits (89), Expect = 3.7
Identities = 24/93 (25%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
Frame = +1
Query: 13027 GRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDA 13206
G++ Y+D L I AD++G++ + ++ + + +A+D N +YW D ++A
Sbjct: 1397 GKVYYTDVFLDV-IRRADLNGSNMETVIGHGLKTTDGLAVDWVARN-LYWTDTGRNTIEA 1454
Query: 13207 VNIDGSERTTVVHDR-HIPYAVDVF--ENHIYW 13296
+DGS R ++++ P A+ VF + +++W
Sbjct: 1455 SRLDGSCRKVLINNSLDEPRAIAVFPRKGYLFW 1487
>gi|47116978|sp|Q9QYP1|LRP4_RAT Low-density lipoprotein
receptor-related protein 4 precursor (Multiple epidermal
growth factor-like domains 7)
Length = 1905
Score = 686 bits (1770), Expect = 0.0
Identities = 507/1764 (28%), Positives = 811/1764 (45%), Gaps = 42/1764 (2%)
Frame = +1
Query: 3124 CQKDPAEKIEQLCSSNSTQFQCKNGR-----CIPKEWKCDGENDCLDESDEIDEKGDKCF 3288
C A +E C+ + F C CIP +W+CDG+NDC D SDE D C
Sbjct: 15 CAHGTASNLE--CACGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDE-----DGCT 67
Query: 3289 HETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNH 3468
T C+ C N K CI +D C +F C N
Sbjct: 68 LPT-CSPLDFHCDNGK-CIRRSWVCDGDNDCEDDSDE-----QDCPPRECEEDEFPCQNG 120
Query: 3469 RCIPEQWKXXXXXXXXXXXXEKLEMCGNATCAANQFSCANGRCIPIYWLCDGDNDCYDGT 3648
CI W E+ +M C+ +F C++G CI +W CDGD DC DG+
Sbjct: 121 YCIRSLWHCDGDNDCGDNSDEQCDM---RKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGS 177
Query: 3649 DEDK--ERCPPVQCSALQFRCANGRQCVPLRNHXXXXXXXXXXXXXXXXAVTAESCTPDQ 3822
DE+ P C+ +F+CA GR C+ L + + + C +
Sbjct: 178 DEESCPSAVPSPPCNLEEFQCAYGR-CI-LDIYHCDGDDDCGDWSDESDCSSHQPCRSGE 235
Query: 3823 FKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKCGNGRCILNNWLCDG 4002
F C SGLC+ A W+ SDE CT+ C+++QF+C +GRC+ +W CDG
Sbjct: 236 FMC-DSGLCVNAGWRCDGDADCDDQSDERN--CTTS-MCTAEQFRCRSGRCVRLSWRCDG 291
Query: 4003 ENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGG 4182
E+DC D SDE + C+ + + +C + C N + CI +LC+G C +DE
Sbjct: 292 EDDCADNSDEEN---CENT-GSPQCASDQFLCWNGR--CIGQRKLCNGVNDCGDNSDESP 345
Query: 4183 ------RCARDLCSADRAGCSFKCHNSPNGPICSCPFGEQLVNKTK-CEPENECLDSSSC 4341
R + C+ + GC+ KC C+C G +L + C+ NEC + C
Sbjct: 346 QQNCRPRTGEENCNVNNGGCAQKCQMIRGAVQCTCHTGYRLTEDGRTCQDVNECAEEGYC 405
Query: 4342 SQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTF 4521
SQ C + + F C C+ GYEL D+R+CK + + +NR I +
Sbjct: 406 SQGCTNSEGAFQCWCEAGYELRPDRRSCKALG--PEPVLLFANRIDIRQVLPHRSEYTLL 463
Query: 4522 GAIVENAIALAWDSLTDRIYWSDIREKKILSANRNGTNATVFIADGLDITEGIALDWVGR 4701
+ENAIAL + + ++WSD+ +IL AN NG+N ++ GL+ G+A+DWV
Sbjct: 464 LNNLENAIALDFHHRRELVFWSDVTLDRILRANLNGSNVEEVVSTGLESPGGLAVDWVHD 523
Query: 4702 NLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQNPCIERA 4881
LYW DS + IEVANL D R +L+ Q++ +PR IA+ P +G ++WTDWG P IE +
Sbjct: 524 KLYWTDSGTSRIEVANL-DGAHRKVLLWQSLEKPRAIALHPMEGTIYWTDWGNTPRIEAS 582
Query: 4882 SMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFV 5061
SMDG+ R+II T ++WPN + +DY R+Y+ D+K I+ N DGS R V+ S+ +
Sbjct: 583 SMDGSGRRIIADTHLFWPNGLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVI--SQGL 640
Query: 5062 QHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIK 5241
HP A+ +FED +Y++D + + K+ G E + + + +HP QP K
Sbjct: 641 PHPFAITVFEDSLYWTDWHTKSINSANKF-TGKNQEIIRNKLHFPMDIHTLHPQRQPAGK 699
Query: 5242 NNPCSTN--PCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNVFGIE 5415
N C N C+HLCL + +N +TC CP G + + C FL+ ++ ++ I
Sbjct: 700 NR-CGDNNGGCTHLCLPSGQN-YTCACPTGFR-KINSHACAQSLDKFLLFARRMDIRRIS 756
Query: 5416 MNSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRS 5595
++ + ++PL+ + +A +D+ + ++ ++TD+ I R+
Sbjct: 757 FDTEDLSD-----DVIPLADVRSAVALDWDSRDDHVY----------WTDVSTDT-ISRA 800
Query: 5596 TVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVILSNDQ 5775
+G + + +++ A L DW L + T IE+ T G +I N
Sbjct: 801 KWDGTGQKVVVDTSLESPA-GLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWEN-- 857
Query: 5776 SXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAI 5955
GY++W D G A K+ RAG+D SN VI S++L + +AI
Sbjct: 858 ----LDRPRDIVVEPMGGYMYWTDWG---ASPKIERAGMDASNRQVIISSNLTWPNGLAI 910
Query: 5956 DTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAFDSIEV 6135
D + R+Y+++A I DG R ++ P GL YG R+++ D SI+
Sbjct: 911 DYGSQRLYWADAGMKTIEFAGLDGSKRKVLIGSQLPHPFGLTLYGQRIYWTDWQTKSIQS 970
Query: 6136 A-TINGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHINNGNCDHICI----PLMF 6300
A + G + ++++ENL +I + PC + NG C H+C+ P F
Sbjct: 971 ADRLTGLDRET----LQENLENLMDIHVFHRQRPPVTTPCAVENGGCSHLCLRSPSPSGF 1026
Query: 6301 AQRTCTCANG--YVKDGQTSCKLFDESFVIVATKTKV------------IGYPIDETQSK 6438
+CTC G + DG+T C SF+I A + V + PI+ T
Sbjct: 1027 ---SCTCPTGINLLLDGKT-CSPGMNSFLIFARRIDVRMVSLDIPYFADVVVPINMTMKN 1082
Query: 6439 GVAMEPIGGLSITGVDYDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIK 6618
+A IG + G Y +S ++ AS + S +I + G T
Sbjct: 1083 TIA---IGVDPLEGKVYWSDSTLHRISRAS----------LDGSQHEDII--TTGLQTTD 1127
Query: 6619 SLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWAD 6798
LA+D I +Y+ D IEV LDG+ RK+L+ ++P +I + ++YW D
Sbjct: 1128 GLAVDAIGRKVYWT--DTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTD 1185
Query: 6799 QGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTP 6978
G+ ++RS +DGS R V++++ + P L VD S + W+DA + I G
Sbjct: 1186 WGENAKLERSGMDGSDRTVLINNNLGWPNGLTVDKTSSQLLWADAHTERIEVADLNGANR 1245
Query: 6979 ELVRSDIASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVA 7158
+ S + G+ L +YWTD + + RA +L V ++L + D+
Sbjct: 1246 HTLVSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKSTGSNVIL-----VRSNLPGLMDIQ 1300
Query: 7159 VFSSNNQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCARGV-LK--GRTCE-EPD 7326
QP + C R C+ LC P +C+C G+ LK G+TC+ P+
Sbjct: 1301 AV-DRAQPLGFNKC----GSRNGGCSHLCLPRPSGF--SCACPTGIQLKGDGKTCDPSPE 1353
Query: 7327 TYIMFSDGDKIIDVAIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNI 7506
TY++FS I ++++ D + P P ++N+ + D D +VY+ + V +++
Sbjct: 1354 TYLLFSSRGSIRRISLDTDDHTD--VHVPVPGLNNVISLDYDSVDGKVYY---TDVFLDV 1408
Query: 7507 SWFSMNNAENPRLVFGASKQPHAKEIRHISDMKLDWLTQKIYFT-TGRGG-KVMAIDTAG 7680
+ N N V G ++ + +DW+ + +Y+T TGR + +D +
Sbjct: 1409 IRRADLNGSNMETVIGHG-------LKTTDGLAVDWVARNLYWTDTGRNTIEASRLDGSC 1461
Query: 7681 EHLSTIASGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESI 7860
+ S D A+A+ P G LFW+D G+ +IER+NL G RKV+++ +
Sbjct: 1462 RKVLINNSLDEPRAIAVFPRKGYLFWTDWGHIA-------KIERANLDGSERKVLINADL 1514
Query: 7861 SLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGY-RAKSLDIWDRWLYMSDP 8037
P + +D+ ++IYW D + IE AD +G+ R+V+ S +L DRW+Y +D
Sbjct: 1515 GWPNGLTLDYDTRRIYWVDAHLDRIESADLNGKLRQVLVSHVSHPFALTQQDRWIYWTDW 1574
Query: 8038 LSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGC 8217
+ + R+DK SG E V+++ + G + + +T C +NGGC
Sbjct: 1575 QTKSIQRVDKYSGRNKETVLAN--VEGLMDIIVVSPQRQTGTNACG--------VNNGGC 1624
Query: 8218 DQLCTVVADDIGLAASKVQCSCND 8289
LC A D C+C D
Sbjct: 1625 SHLCFARASDF-------VCACPD 1641
Score = 470 bits (1209), Expect = e-130
Identities = 323/1036 (31%), Positives = 481/1036 (46%), Gaps = 57/1036 (5%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDT-----YTWH-- 315
C+ DF C++GKCIR W P C+ D++ C WH
Sbjct: 71 CSPLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPCQNGYCIRSLWHCD 130
Query: 316 --------------------------SVSCIAEYQRCDNITDCADGSDEKDCPASTVD-- 411
SCIAE+ CD TDC DGSDE+ CP++
Sbjct: 131 GDNDCGDNSDEQCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEESCPSAVPSPP 190
Query: 412 CSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQ 591
C+ + F CA GR D+ CDG DC D SDE D CS +H C +F C D C+
Sbjct: 191 CNLEE-FQCAYGRCILDIYH-CDGDDDCGDWSDESD-CS-SHQPCRSGEFMC-DSGLCVN 245
Query: 592 KSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDEC 771
W CDG DC D SDE + C CTA +F+C++ RC +RCD DDC DNSDE+ C
Sbjct: 246 AGWRCDGDADCDDQSDERN-CTTSMCTAEQFRCRSGRCVRLSWRCDGEDDCADNSDEENC 304
Query: 772 ---GEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLG-------- 918
G +C ++ C G CI Q KLC+G DC D +DE QN P G
Sbjct: 305 ENTGSPQCASDQFLC-WNGRCIGQRKLCNGVNDCGDNSDESP-QQNCRPRTGEENCNVNN 362
Query: 919 --CQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCL 1092
C C +CTC +GY+L + RTC D+NECAE GYC Q C N F C C
Sbjct: 363 GGCAQKCQMIRGAVQCTCHTGYRLTED-GRTCQDVNECAEEGYCSQGCTNSEGAFQCWCE 421
Query: 1093 GDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKLASGE 1272
G + R C + + + LF A R + ++ P E L + E
Sbjct: 422 A-----------GYELRPDRRSCKALGPEPVLLF-ANRIDIRQVLPHR-SEYTLLLNNLE 468
Query: 1273 FIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNT 1452
+DF + +FW+D A+++ S ++++ L P LAVDW+ +
Sbjct: 469 NAIALDFHHRRELVFWSDVTLDRILRANLNG----SNVEEVVSTGLESPGGLAVDWVHDK 524
Query: 1453 LYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFT---NQLKLEAAAM 1623
LY +SG+ RI+V++ DG R VLL L P IAL P+ G +++T N ++EA++M
Sbjct: 525 LYWTDSGTSRIEVANLDGAHRKVLLWQSLEKPRAIALHPMEGTIYWTDWGNTPRIEASSM 584
Query: 1624 DGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRR-IVAQGMNVVP 1800
DG+ RR + +TH +G+ +D +R+YWVD K +E + G+ R+ +++QG+ P
Sbjct: 585 DGSGRRIIADTHLFWPNGLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVISQGL---P 641
Query: 1801 HPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPG 1980
HPF + +F+ LYWTDW + KF + + N + FPM I HP QP G
Sbjct: 642 HPFAITVFEDSLYWTDWHTKSINSANKFTGKNQEIIRNKLH--FPMDIHTLHPQRQPA-G 698
Query: 1981 QSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGKRCIDSID-YLL 2157
++ C N C +C+ S G Y CACP G + +N C S+D +LL
Sbjct: 699 KNRC-------GDNNGGCTHLCLPS------GQNYTCACPTGFRKINSHACAQSLDKFLL 745
Query: 2158 FSSNKIVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIY 2337
F+ +R I + + L++ V+P++ + ++ D + ++ D+ +TI
Sbjct: 746 FARRMDIRRI--SFDTEDLSDDVIPLADVRSA-----VALDWDSRDDHVYWTDVSTDTIS 798
Query: 2338 RIRPDGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVR 2517
R + DG G V+ T + ++ DW++ +LY+ D + +EV + D +R
Sbjct: 799 RAKWDGTGQKVVVDTSLESPAGLAIDWVTNKLYWTDAGTDRIEV--------ANTDGSMR 850
Query: 2518 RQLITELRD-PVSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAI 2694
LI E D P +VV P G +++ + I R +D N QVI ++ L P+ +AI
Sbjct: 851 TVLIWENLDRPRDIVVEPMGGYMYWTDWGASPKIERAGMDASNRQVIISSNLTWPNGLAI 910
Query: 2695 DFAENRLCWGDTLLKTISCMDFDG-KNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRR 2871
D+ RL W D +KTI DG K V + P P +T+ + IY+ + SI+
Sbjct: 911 DYGSQRLYWADAGMKTIEFAGLDGSKRKVLIGSQLPHPFGLTLYGQRIYWTDWQTKSIQS 970
Query: 2872 VHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQ--CTQLCFATPS 3045
+ G + ++E + ++ + Q P+ PC C+ LC +PS
Sbjct: 971 ADRLTGLDRETLQE---NLENLMDIHVFHRQRPPVTT-----PCAVENGGCSHLCLRSPS 1022
Query: 3046 ESHPNELEAKCACRQG 3093
S C C G
Sbjct: 1023 PS-----GFSCTCPTG 1033
Score = 457 bits (1176), Expect = e-126
Identities = 271/769 (35%), Positives = 387/769 (50%), Gaps = 13/769 (1%)
Frame = +1
Query: 8575 CGDGS-DELDCPSAVACAEGTFPCSNGH-----CINQTKVCDGHNDCHDEQVSDESLATC 8736
C G+ L+C AC F C+ CI CDG NDC D SDE T
Sbjct: 15 CAHGTASNLEC----ACGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDH--SDEDGCTL 68
Query: 8737 PGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGR 8916
P C + C N CI+ + +CDG +DC D +DE C ++C + C +G
Sbjct: 69 P----TCSPLDFHCDNGK-CIRRSWVCDGDNDCEDDSDEQD--CPPRECEEDEFPCQNGY 121
Query: 8917 CIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXX 9096
CI W CDGDNDC D DE + C D F+C + CI+ +
Sbjct: 122 CIRSLWHCDGDNDCGDNSDEQ-------CDMRKC-SDKEFRCSDGSCIAEHWYCDGDTDC 173
Query: 9097 XXXXXXHS-RHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTE 9273
S + C +EF C CI + CDGD C DES
Sbjct: 174 KDGSDEESCPSAVPSPPCNLEEFQCAYG--------RCILDIYHCDGDDDCGDWSDESD- 224
Query: 9274 LCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCANHK 9453
C + + C GEF C + C+++ W CDGD DC D SDE NCT S C + F+C + +
Sbjct: 225 -CSSHQP-CRSGEFMCDSGLCVNAGWRCDGDADCDDQSDER-NCTTSMCTAEQFRCRSGR 281
Query: 9454 CVPNSWKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFD 9633
CV SW+CDG DDC D SDE++C +N+ S Q C++ QF C +G CI K+C+ D
Sbjct: 282 CVRLSWRCDGEDDCADNSDEENC-ENTGSPQ----CASDQFLCWNGRCIGQRKLCNGVND 336
Query: 9634 CTDRSDESSLCFI------DECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCH 9795
C D SDES + C++ C QKC ++ +C C G+ + D ++C
Sbjct: 337 CGDNSDESPQQNCRPRTGEENCNVNNGG-CAQKCQMIRGAVQCTCHTGYRLT-EDGRTCQ 394
Query: 9796 NVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIR 9975
+VNEC E CSQ C + G+++C C GY+L D SCK + PEP L AN+ IR
Sbjct: 395 DVNECAEE-GYCSQGCTNSEGAFQCWCEAGYELRPDRRSCKA--LGPEPVLLFANRIDIR 451
Query: 9976 KISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVL 10155
++ ++Y L +N ++LD + + D R+LR +L+ S+ E V+
Sbjct: 452 QVLPHRSEYTLLLNNLENAIALDFHHRRELVFWSDVTLDRILRANLNG-----SNVEEVV 506
Query: 10156 RHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKG 10335
+ G+AVDWV KLY + I V LDG K L+ +++P+AI +HP +G
Sbjct: 507 STGLESPGGLAVDWVHDKLYWTDSGTSRIEVANLDGAHRKVLLWQSLEKPRAIALHPMEG 566
Query: 10336 YLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNE 10515
+++T+W P I ++DGS +A+ L WPN + IDY R++W DA +
Sbjct: 567 TIYWTDWGNTPRIEASSMDGSGRRI-----IADTHLFWPNGLTIDYAGRRMYWVDAKHHV 621
Query: 10516 IGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTV 10695
I + DG+ R+ + +Q H ++ VF+D LYW DW+ + + +K+TGKN+ I++ +
Sbjct: 622 IERANLDGSHRKAVISQGLPHPFAITVFEDSLYWTDWHTKSINSANKFTGKNQEIIRNKL 681
Query: 10696 QLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQF 10842
P D+ +HP RQPA N CGDNNGGC+HLCL G YTC+CP F
Sbjct: 682 HFPMDIHTLHPQRQPAGKNRCGDNNGGCTHLCL--PSGQNYTCACPTGF 728
Score = 387 bits (993), Expect = e-105
Identities = 273/1015 (26%), Positives = 481/1015 (46%), Gaps = 8/1015 (0%)
Frame = +1
Query: 4312 ENECLDSSS-CSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRN--RI 4482
+N C D++ C+ C +TC+C G+ ++ C A ++ ++ + RI
Sbjct: 699 KNRCGDNNGGCTHLCLPSGQNYTCACPTGFR-KINSHAC--AQSLDKFLLFARRMDIRRI 755
Query: 4483 YYSDHKLDNWHTFGAIVENAIALAWDSLTDRIYWSDIREKKILSANRNGTNATVFIADGL 4662
+ L + A V +A+AL WDS D +YW+D+ I A +GT V + L
Sbjct: 756 SFDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDGTGQKVVVDTSL 815
Query: 4663 DITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMF 4842
+ G+A+DWV LYW D+ + IEVAN D RT+L+ +N+ +PR I V+P G M+
Sbjct: 816 ESPAGLAIDWVTNKLYWTDAGTDRIEVANT-DGSMRTVLIWENLDRPRDIVVEPMGGYMY 874
Query: 4843 WTDWGQNPCIERASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDG 5022
WTDWG +P IERA MD ++RQ+I+ + + WPN +A+DY + R+Y+AD+ + I+F DG
Sbjct: 875 WTDWGASPKIERAGMDASNRQVIISSNLTWPNGLAIDYGSQRLYWADAGMKTIEFAGLDG 934
Query: 5023 SGRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALG 5202
S R ++ S + HP L ++ +Y++D + + +Q + G E +
Sbjct: 935 SKRKVLIGSQ--LPHPFGLTLYGQRIYWTDWQTKSIQSADRL-TGLDRETLQENLENLMD 991
Query: 5203 VVAVHPVLQPVIKNNPCSTNPCSHLCLLN-NKNTFTCKCPMGEKLDASGKKCIDDAKPFL 5379
+ H PV CSHLCL + + + F+C CP G L GK C FL
Sbjct: 992 IHVFHRQRPPVTTPCAVENGGCSHLCLRSPSPSGFSCTCPTGINLLLDGKTCSPGMNSFL 1051
Query: 5380 VIIQKTNVFGIEMNSASEKETPVLAG-MVPLS-GLGNAFDAAYDALSEEMFILEHTNHAK 5553
+ ++ +V + + + P A +VP++ + N D L +++ + T H
Sbjct: 1052 IFARRIDVRMVSL------DIPYFADVVVPINMTMKNTIAIGVDPLEGKVYWSDSTLH-- 1103
Query: 5554 TLAQITTDSAIYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRT 5733
+++ + D + + + G +T L D GR + + T IE+
Sbjct: 1104 RISRASLDGSQHEDIITTGLQT----------TDGLAVDAIGRKVYWTDTGTNRIEVGNL 1153
Query: 5734 QGKQYRSVILSNDQSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLV 5913
G + ++ N S G+++W D G +AK+ R+G+DGS+ V
Sbjct: 1154 DGSMRKVLVWQNLDS------PRAIVLYHEMGFMYWTDWG---ENAKLERSGMDGSDRTV 1204
Query: 5914 IASNDLAELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGD 6093
+ +N+L + + +D T++++ +++A RI +G +RH ++S + P GL
Sbjct: 1205 LINNNLGWPNGLTVDKTSSQLLWADAHTERIEVADLNGANRHTLVSP-VQHPYGLTLLDS 1263
Query: 6094 RLFYADSAFDSIEVATINGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHINNGNC 6273
+++ D SI A + S + ++ L +I+A+ + C NG C
Sbjct: 1264 YIYWTDWQTRSIHRADKSTGSNV---ILVRSNLPGLMDIQAVDRAQPLGFNKCGSRNGGC 1320
Query: 6274 DHICIPLMFAQRTCTCANG-YVKDGQTSCKLFDESFVIVATKTKVIGYPIDETQSKGVAM 6450
H+C+P + +C C G +K +C E++++ +++ + +D V +
Sbjct: 1321 SHLCLPRP-SGFSCACPTGIQLKGDGKTCDPSPETYLLFSSRGSIRRISLDTDDHTDVHV 1379
Query: 6451 EPIGGL-SITGVDYDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIKSLA 6627
P+ GL ++ +DYD +Y + I + S+ VI G T LA
Sbjct: 1380 -PVPGLNNVISLDYDSVDGKVYYTDV--FLDVIRRADLNGSNMETVI--GHGLKTTDGLA 1434
Query: 6628 IDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQ 6807
+DW+ N+Y+ D R IE S+LDG+ RK+L+ + P +IAV P YL+W D G
Sbjct: 1435 VDWVARNLYWT--DTGRNTIEASRLDGSCRKVLINNSLDEPRAIAVFPRKGYLFWTDWGH 1492
Query: 6808 KPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPELV 6987
I+R+ LDGS R+V++++ + P L +D ++ IYW DA +D I G +++
Sbjct: 1493 IAKIERANLDGSERKVLINADLGWPNGLTLDYDTRRIYWVDAHLDRIESADLNGKLRQVL 1552
Query: 6988 RSDIASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFS 7167
S ++ + + +YWTD + + + R + + TV A+++ + D+ V S
Sbjct: 1553 VSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGR-----NKETVLANVEGLMDIIVVS 1607
Query: 7168 SNNQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCARGVLKGRTCEEPDTY 7332
Q ++ C + + C+ LCFA C+C +EPD++
Sbjct: 1608 PQRQ-TGTNACGVNN----GGCSHLCFAR--ASDFVCACP---------DEPDSH 1646
Score = 327 bits (837), Expect = 7e-87
Identities = 236/776 (30%), Positives = 340/776 (43%), Gaps = 47/776 (6%)
Frame = +1
Query: 11359 ECAQIECKKGWTRCSSSY----RCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCA 11526
ECA C + C+ S CIP C+G +DC D+SDED PTC + +F C
Sbjct: 24 ECA---CGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDEDGCTLPTCSPL-DFHC- 78
Query: 11527 TSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQ 11706
+GKCI R W+CD +NDC D+SDE D R C E EF C +G CI CDG
Sbjct: 79 DNGKCIRRSWVCDGDNDCEDDSDEQDCP----PRECEEDEFPCQNGYCIRSLWHCDGDND 134
Query: 11707 CSDGLDESQCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCED-VSRRTCSP 11883
C D DE QC +R+C +C DG+CIAEH +CD DC + +DE C V C+
Sbjct: 135 CGDNSDE-QCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEESCPSAVPSPPCNL 193
Query: 11884 FEFECANSVCIPRKFMXXXXXXXXXXSDETSSE----CRSAQ--CDPPL----------- 12012
EF+CA CI + SDE+ CRS + CD L
Sbjct: 194 EEFQCAYGRCILDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMCDSGLCVNAGWRCDGD 253
Query: 12013 --------------------RFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSFS 12132
+FRC R C+ + C+G +DC N SDE C +
Sbjct: 254 ADCDDQSDERNCTTSMCTAEQFRCRSGR-CVRLSWRCDGEDDCADN--SDEE--NCENTG 308
Query: 12133 EYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEI---GCSKHGGKTSCEAFGNNGGC 12303
C+SDQF C NG+C+ C+ +DCGD SDE C G+ +C NNGGC
Sbjct: 309 S-PQCASDQFLCWNGRCIGQRKLCNGVNDCGDNSDESPQQNCRPRTGEENCNV--NNGGC 365
Query: 12304 KHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGSYLCRCHEDY 12483
C +R C C G+R + + C D++ECA C+Q C N++G++ C C Y
Sbjct: 366 AQKCQMIRGAVQCTCHTGYRLT-EDGRTCQDVNECAEEGYCSQGCTNSEGAFQCWCEAGY 424
Query: 12484 ENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXX 12663
E + C+A G ++ + Q+ H R
Sbjct: 425 ELR-----PDRRSCKALGPEPVLLFANRIDIRQVLPH-----RSEYTLLLNNLENAIALD 474
Query: 12664 XXPRKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFI 12843
R+EL++W S+ T+ R AN N S+ + + + P +AVD+ L+
Sbjct: 475 FHHRRELVFW---SDVTLDRILRANLNGSNVEEVVSTGLES----PGGLAVDWVHDKLYW 527
Query: 12844 AAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPS 13023
+ T I V DG + K ++ L++P A+ P
Sbjct: 528 T-----------------------DSGTSRIEVANLDGAHRKVLLWQSLEKPRAIALHPM 564
Query: 13024 AGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVD 13203
G I ++D G +IE + MDG+ R+II +F P + ID G R+YWVD K+ ++
Sbjct: 565 EGTIYWTDWGNTPRIEASSMDGSGRRIIADTHLFWPNGLTIDYA-GRRMYWVDAKHHVIE 623
Query: 13204 AVNIDGSERTTVV-HDRHIPYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLED 13380
N+DGS R V+ P+A+ VFE+ +YW +K++ +KF ++ + L
Sbjct: 624 RANLDGSHRKAVISQGLPHPFAITVFEDSLYWTDWHTKSINSANKFTGKNQEIIRNKLHF 683
Query: 13381 GHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPS-TGFACLCPDGIVPQLDGSCA 13545
+ + + G C+HLC LPS + C CP G +CA
Sbjct: 684 PMDIHTLHPQRQPAGKNRCGDNNGGCTHLC--LPSGQNYTCACPTGFRKINSHACA 737
Score = 248 bits (633), Expect = 3e-63
Identities = 198/732 (27%), Positives = 333/732 (45%), Gaps = 12/732 (1%)
Frame = +1
Query: 1018 NECAEF-GYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLF 1194
N C + G C LC +TC+C G K N + + + DK LF
Sbjct: 700 NRCGDNNGGCTHLCLPSGQNYTCAC---------PTGFRKIN----SHACAQSLDKFLLF 746
Query: 1195 VARREGLYRLNPKNPD--EEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDE 1368
ARR + R++ D ++V LA +D+D D ++WTD + A D
Sbjct: 747 -ARRMDIRRISFDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDGT 805
Query: 1369 GEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLP 1548
G+ K + SL P LA+DW+TN LY ++G+ RI+V++ DG RTVL+ + L P
Sbjct: 806 GQ----KVVVDTSLESPAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRP 861
Query: 1549 LDIALDPLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVD 1719
DI ++P+ G M++T+ K+E A MD +NR+ +++++ +G+ +D ++R+YW D
Sbjct: 862 RDIVVEPMGGYMYWTDWGASPKIERAGMDASNRQVIISSNLTWPNGLAIDYGSQRLYWAD 921
Query: 1720 PKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKF-GSDT 1896
+ +E G+ R+++ +PHPFGL L+ Q +YWTDW + ++ G D
Sbjct: 922 AGMKTIEFAGLDGSKRKVLIGSQ--LPHPFGLTLYGQRIYWTDWQTKSIQSADRLTGLDR 979
Query: 1897 KLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCT--NADCEGMCILSKDNGG 2070
+ L N EN M I +H P + PC N C +C+ S G
Sbjct: 980 ETLQENLEN---LMDIHVFHRQRPP-----------VTTPCAVENGGCSHLCLRSPSPSG 1025
Query: 2071 FGVGYKCACPIG-QKLVNGKRCIDSID-YLLFSSNKIVRGIFPEINEKALAEAVLPISPI 2244
F C CP G L++GK C ++ +L+F+ VR + +I A+ V+PI+
Sbjct: 1026 F----SCTCPTGINLLLDGKTCSPGMNSFLIFARRIDVRMVSLDI--PYFADVVVPINMT 1079
Query: 2245 SQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWIS 2424
+ I + D +++D + I R DG ++ T ++ D I
Sbjct: 1080 MKNTIA----IGVDPLEGKVYWSDSTLHRISRASLDGSQHEDIITTGLQTTDGLAVDAIG 1135
Query: 2425 KQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITE-LRDPVSVVVHPWKGLLFYAEAM 2601
+++Y+ D N +EV + D +R+ L+ + L P ++V++ G +++ +
Sbjct: 1136 RKVYWTDTGTNRIEVGNL--------DGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTDWG 1187
Query: 2602 RPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVK 2781
A + R +DG + V+ N LG P+ + +D ++L W D + I D +G N
Sbjct: 1188 ENAKLERSGMDGSDRTVLINNNLGWPNGLTVDKTSSQLLWADAHTERIEVADLNGANRHT 1247
Query: 2782 LDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSH 2961
L P +T+++ YIY+ + SI R K G +VR ++ L
Sbjct: 1248 LVSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKSTGSNVILVRS------NLPGLMDIQA 1301
Query: 2962 QNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINKENNHSCQKDPA 3141
++ P + R C+ LC PS CAC G + K + +C DP+
Sbjct: 1302 VDRAQPLGFNKCGSRNGGCSHLCLPRPS-------GFSCACPTGIQL-KGDGKTC--DPS 1351
Query: 3142 EKIEQLCSSNST 3177
+ L SS +
Sbjct: 1352 PETYLLFSSRGS 1363
Score = 233 bits (593), Expect = 1e-58
Identities = 128/349 (36%), Positives = 186/349 (52%), Gaps = 3/349 (0%)
Frame = +1
Query: 9802 NECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKI 9981
N+C GCS C + + C C G QL D +C + PE + L +++ IR+I
Sbjct: 1311 NKCGSRNGGCSHLCLPRPSGFSCACPTGIQLKGDGKTC---DPSPETYLLFSSRGSIRRI 1367
Query: 9982 SIDGNKY---ELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETV 10152
S+D + + + G +NV+SLD D + K Y D + R DL+ S+ ETV
Sbjct: 1368 SLDTDDHTDVHVPVPGLNNVISLDYDSVDGKVYYTDVFLDVIRRADLNG-----SNMETV 1422
Query: 10153 LRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGK 10332
+ H + T+G+AVDWV R LY + +I LDG K LI + + +P+AI V P K
Sbjct: 1423 IGHGLKTTDGLAVDWVARNLYWTDTGRNTIEASRLDGSCRKVLINNSLDEPRAIAVFPRK 1482
Query: 10333 GYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLN 10512
GYLF+T+W I R LDGS L DLGWPN + +DY + R++W DAHL+
Sbjct: 1483 GYLFWTDWGHIAKIERANLDGSERK-----VLINADLGWPNGLTLDYDTRRIYWVDAHLD 1537
Query: 10513 EIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKT 10692
I D +G R + SH ++ D ++YW DW + + R DK++G+N+ +
Sbjct: 1538 RIESADLNGK-LRQVLVSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVLAN 1596
Query: 10693 VQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQ 10839
V+ D+ +V P RQ N CG NNGGCSHLC A + + C+CPD+
Sbjct: 1597 VEGLMDIIVVSPQRQTG-TNACGVNNGGCSHLCF--ARASDFVCACPDE 1642
Score = 223 bits (569), Expect = 8e-56
Identities = 203/734 (27%), Positives = 325/734 (43%), Gaps = 19/734 (2%)
Frame = +1
Query: 994 FHRTCSDINE-CA-EFGYCDQLCANHRP--GFTCSCLGDCFTLQMEHGPGKDNLTMRGYC 1161
FHR + CA E G C LC GF+C+C P NL + G
Sbjct: 995 FHRQRPPVTTPCAVENGGCSHLCLRSPSPSGFSCTC------------PTGINLLLDGKT 1042
Query: 1162 VSNNADKMKLFVARREGLYRLN---PKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRL 1332
S + +F ARR + ++ P D V + + I D + K++W+D
Sbjct: 1043 CSPGMNSFLIF-ARRIDVRMVSLDIPYFADVVVPINMTMKNTIAIGVDPLEGKVYWSDST 1101
Query: 1333 AHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGER 1512
H A +D SQ + + L LAVD I +Y ++G+ RI+V + DG
Sbjct: 1102 LHRISRASLDG----SQHEDIITTGLQTTDGLAVDAIGRKVYWTDTGTNRIEVGNLDGSM 1157
Query: 1513 RTVLLADGLTLPLDIALDPLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHTHQVSGIV 1683
R VL+ L P I L G M++T+ KLE + MDG++R L+N + +G+
Sbjct: 1158 RKVLVWQNLDSPRAIVLYHEMGFMYWTDWGENAKLERSGMDGSDRTVLINNNLGWPNGLT 1217
Query: 1684 VDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLG 1863
VD T+ ++ W D +R+E D G +R + ++ V HP+GL L D Y+YWTDW
Sbjct: 1218 VDKTSSQLLWADAHTERIEVADLNGANRHTL---VSPVQHPYGLTLLDSYIYWTDWQTRS 1274
Query: 1864 VIQVEKF-GSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEG 2040
+ + +K GS+ L+ SN + + P+ G ++C + N C
Sbjct: 1275 IHRADKSTGSNVILVRSNLPGLMDIQAVDRAQPL-----GFNKCGSR-------NGGCSH 1322
Query: 2041 MCILSKDNGGFGVGYKCACPIGQKLV-NGKRCIDSID-YLLFSSNKIVRGIFPEINEKAL 2214
+C+ G+ CACP G +L +GK C S + YLLFSS +R I + ++
Sbjct: 1323 LCLPRPS------GFSCACPTGIQLKGDGKTCDPSPETYLLFSSRGSIRRISLDTDDHTD 1376
Query: 2215 AEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVL---VTH 2385
+P + ++ D +Y D+ + I R +G V+ +
Sbjct: 1377 VHVPVP-------GLNNVISLDYDSVDGKVYYTDVFLDVIRRADLNGSNMETVIGHGLKT 1429
Query: 2386 NDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITE-LRDPVSVVV 2562
DGL + DW+++ LY+ D RN++E ++ D R+ LI L +P ++ V
Sbjct: 1430 TDGL---AVDWVARNLYWTDTGRNTIEASRL--------DGSCRKVLINNSLDEPRAIAV 1478
Query: 2563 HPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKT 2742
P KG LF+ + A I R ++DG +V+ N LG P+ + +D+ R+ W D L
Sbjct: 1479 FPRKGYLFWTDWGHIAKIERANLDGSERKVLINADLGWPNGLTLDYDTRRIYWVDAHLDR 1538
Query: 2743 ISCMDFDGKNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGA 2922
I D +GK L P A+T + +IY+ + SI+RV K +G + V A
Sbjct: 1539 IESADLNGKLRQVLVSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVL---A 1595
Query: 2923 DERSIFSLKACSHQNQPIPDDSREHPCRASQ--CTQLCFATPSESHPNELEAKCACRQGF 3096
+ + + S Q Q + + C + C+ LCFA S + CAC
Sbjct: 1596 NVEGLMDIIVVSPQRQ-----TGTNACGVNNGGCSHLCFARAS-------DFVCACP--- 1640
Query: 3097 MINKENNHSCQKDP 3138
++ ++H C P
Sbjct: 1641 --DEPDSHPCSLVP 1652
Score = 195 bits (496), Expect = 2e-47
Identities = 110/361 (30%), Positives = 171/361 (46%), Gaps = 3/361 (0%)
Frame = +1
Query: 9802 NECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKI 9981
N C + GC+ C +Y C C G++ + H+C ++ + F L A + IR+I
Sbjct: 700 NRCGDNNGGCTHLCLPSGQNYTCACPTGFR-KINSHACAQSL---DKFLLFARRMDIRRI 755
Query: 9982 SIDGNKYE---LAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETV 10152
S D + + V+LD D + Y D + R D + + V
Sbjct: 756 SFDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDG-----TGQKVV 810
Query: 10153 LRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGK 10332
+ ++ G+A+DWV KLY + I V DG LI + + +P+ IVV P
Sbjct: 811 VDTSLESPAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRPRDIVVEPMG 870
Query: 10333 GYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLN 10512
GY+++T+W P I R +D S + +L WPN +AIDY S RL+W DA +
Sbjct: 871 GYMYWTDWGASPKIERAGMDASNRQV-----IISSNLTWPNGLAIDYGSQRLYWADAGMK 925
Query: 10513 EIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKT 10692
I F DG+ R+ + + H + ++ +YW DW + + D+ TG + L++
Sbjct: 926 TIEFAGLDGSKRKVLIGSQLPHPFGLTLYGQRIYWTDWQTKSIQSADRLTGLDRETLQEN 985
Query: 10693 VQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTCE 10872
++ D+ + H R P PC NGGCSHLCL +G++C+CP LL D KTC
Sbjct: 986 LENLMDIHVFHRQRPPV-TTPCAVENGGCSHLCLRSPSPSGFSCTCPTGINLLLDGKTCS 1044
Query: 10873 P 10875
P
Sbjct: 1045 P 1045
Score = 191 bits (486), Expect = 3e-46
Identities = 112/357 (31%), Positives = 169/357 (46%), Gaps = 6/357 (1%)
Frame = +1
Query: 9826 GCSQKC--DDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNK 9999
GCS C + C C G L D +C F + A + +R +S+D
Sbjct: 1012 GCSHLCLRSPSPSGFSCTCPTGINLLLDGKTCSPGM---NSFLIFARRIDVRMVSLDIPY 1068
Query: 10000 YELAAQGFD----NVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNV 10167
+ + N +++ +D E K Y D R+ R LD S +E ++ +
Sbjct: 1069 FADVVVPINMTMKNTIAIGVDPLEGKVYWSDSTLHRISRASLDG-----SQHEDIITTGL 1123
Query: 10168 YGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFF 10347
T+G+AVD +GRK+Y + I V LDG K L+ + P+AIV++ G++++
Sbjct: 1124 QTTDGLAVDAIGRKVYWTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYW 1183
Query: 10348 TEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFM 10527
T+W + R +DGS L ++LGWPN + +D S +L W DAH I
Sbjct: 1184 TDWGENAKLERSGMDGSDRT-----VLINNNLGWPNGLTVDKTSSQLLWADAHTERIEVA 1238
Query: 10528 DFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPN 10707
D +G RH H + + D Y+YW DW R + R DK TG N +++ +
Sbjct: 1239 DLNG-ANRHTLVSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKSTGSNVILVRSNLPGLM 1297
Query: 10708 DLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTCEPN 10878
D++ V QP N CG NGGCSHLCL +G++C+CP L D KTC+P+
Sbjct: 1298 DIQAV-DRAQPLGFNKCGSRNGGCSHLCL--PRPSGFSCACPTGIQLKGDGKTCDPS 1351
Score = 159 bits (403), Expect = 1e-36
Identities = 117/387 (30%), Positives = 161/387 (41%), Gaps = 22/387 (5%)
Frame = +1
Query: 8383 PYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCN 8562
P +F C +G CI CD DC D SDE C R C ED C N CI S C+
Sbjct: 73 PLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQD--CPPRECEEDEFPCQNGYCIRSLWHCD 130
Query: 8563 HIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPG 8742
+DCGD SDE C C++ F CS+G CI + CDG DC D + + P
Sbjct: 131 GDNDCGDNSDE-QCDMR-KCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEESCPSAVPS 188
Query: 8743 LPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCI 8922
P C + +C CI CDG DDCGD +DE+ +Q C C SG C+
Sbjct: 189 PP--CNLEEFQCAYGR-CILDIYHCDGDDDCGDWSDESDC-SSHQPCRSGEFMCDSGLCV 244
Query: 8923 PETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXX 9102
W+CDGD DC D DE NCT + +C + F+C + +C+ ++
Sbjct: 245 NAGWRCDGDADCDDQSDE--RNCTTS----MCTAEQ-FRCRSGRCVRLSWRCDGEDDCAD 297
Query: 9103 XXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTEL-C 9279
+ G+ C +F C + CI + LC+G C DES + C
Sbjct: 298 NSDEENCENTGSPQCASDQFLCWNG--------RCIGQRKLCNGVNDCGDNSDESPQQNC 349
Query: 9280 --KTEKKECNKGEFRCSN---------QHCIHSTWE-------CDGDNDCLDGSDEHANC 9405
+T ++ CN C+ Q H+ + C N+C + C
Sbjct: 350 RPRTGEENCNVNNGGCAQKCQMIRGAVQCTCHTGYRLTEDGRTCQDVNECAEEGYCSQGC 409
Query: 9406 TYSSCQPDFFQC---ANHKCVPNSWKC 9477
T S FQC A ++ P+ C
Sbjct: 410 TNSE---GAFQCWCEAGYELRPDRRSC 433
Score = 150 bits (379), Expect = 9e-34
Identities = 112/340 (32%), Positives = 147/340 (42%), Gaps = 10/340 (2%)
Frame = +1
Query: 8362 PAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCI 8541
P +EC F C +G CI CD DC D SDE C+ R C + C++ CI
Sbjct: 106 PPRECEED-EFPCQNGYCIRSLWHCDGDNDCGDNSDEQ---CDMRKCSDKEFRCSDGSCI 161
Query: 8542 DSAKKCNHIDDCGDGSDELDCPSAV---ACAEGTFPCSNGHCINQTKVCDGHNDCHDEQV 8712
C+ DC DGSDE CPSAV C F C+ G CI CDG +DC D
Sbjct: 162 AEHWYCDGDTDCKDGSDEESCPSAVPSPPCNLEEFQCAYGRCILDIYHCDGDDDCGD--W 219
Query: 8713 SDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQH 8892
SDES + CR + C ++ +C+ CDG DC D++DE C C
Sbjct: 220 SDESDCSSHQ---PCRSGEFMC-DSGLCVNAGWRCDGDADCDDQSDERN--CTTSMCTAE 273
Query: 8893 YVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAF 9072
RC SGRC+ +W+CDG++DC+D DE NC +T G C D F C N +CI +
Sbjct: 274 QFRCRSGRCVRLSWRCDGEDDCADNSDE--ENCENT-GSPQCASDQ-FLCWNGRCIGQRK 329
Query: 9073 IXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAG 9252
+ + C RT E +C N K + I A C TC
Sbjct: 330 LCNGVNDCGDNSDESPQQNCRPRT---GEENCNVNNGGCAQKCQMIRGAVQC----TCHT 382
Query: 9253 GE--DESTELCK-----TEKKECNKGEFRCSNQHCIHSTW 9351
G E C+ E+ C++G C+N W
Sbjct: 383 GYRLTEDGRTCQDVNECAEEGYCSQG---CTNSEGAFQCW 419
Score = 131 bits (329), Expect = 6e-28
Identities = 100/313 (31%), Positives = 128/313 (39%), Gaps = 7/313 (2%)
Frame = +1
Query: 11590 SDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQ 11769
+ L+ +CG + C+ S + CIP CDG C D DE CTL C P
Sbjct: 20 ASNLECACGRSHFTCAVSAL--GECTCIPAQWQCDGDNDCGDHSDEDGCTLPTCSPLDFH 77
Query: 11770 CDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFECANSVCIPRKFMXXXXXX 11949
CD+G CI CD DC + +DE C R C EF C N CI +
Sbjct: 78 CDNGKCIRRSWVCDGDNDCEDDSDEQDCPP---RECEEDEFPCQNGYCIRSLWHCDGDND 134
Query: 11950 XXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSF 12129
SDE +C +C FRC+ C+ C+G DC D SDE C S
Sbjct: 135 CGDNSDE---QCDMRKCSDK-EFRCSDGS-CIAEHWYCDGDTDC--KDGSDEE--SCPSA 185
Query: 12130 SEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKH 12309
C+ ++F+CA G+C+ CD DDCGD SDE CS H S E ++G C
Sbjct: 186 VPSPPCNLEEFQCAYGRCILDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMCDSGLC-- 243
Query: 12310 ICTDVRDGFYCHCRDGFRP-DPQSPKECIDIDECAG------NNTCTQLCLNTKGSYLCR 12468
V G+ C DG D QS + C + C +L G C
Sbjct: 244 ----VNAGWRC---DGDADCDDQSDERNCTTSMCTAEQFRCRSGRCVRLSWRCDGEDDCA 296
Query: 12469 CHEDYENNVVVGS 12507
+ D EN GS
Sbjct: 297 DNSDEENCENTGS 309
Score = 111 bits (277), Expect = 6e-22
Identities = 80/290 (27%), Positives = 131/290 (44%), Gaps = 2/290 (0%)
Frame = +1
Query: 12673 RKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAV 12852
R + +YW D S TI R+ GQK+ VD + P +A+D+ T L+
Sbjct: 783 RDDHVYWTDVSTDTISRA-----KWDGTGQKVVVDTSLES--PAGLAIDWVTNKLYWT-- 833
Query: 12853 SENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGR 13032
+ T I V DG ++ +L +P ++ P G
Sbjct: 834 ---------------------DAGTDRIEVANTDGSMRTVLIWENLDRPRDIVVEPMGGY 872
Query: 13033 ICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVN 13212
+ ++D G KIE A MD ++RQ+I+ + P +AID G R+YW D + ++
Sbjct: 873 MYWTDWGASPKIERAGMDASNRQVIISSNLTWPNGLAIDYG-SQRLYWADAGMKTIEFAG 931
Query: 13213 IDGSERTTVVHDR-HIPYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHT 13389
+DGS+R ++ + P+ + ++ IYW ++K++ D+ L +LE+
Sbjct: 932 LDGSKRKVLIGSQLPHPFGLTLYGQRIYWTDWQTKSIQSADRLTGLDRETLQENLENLMD 991
Query: 13390 VRVSQKYAKDTQRTVSGCERAQCSHLCVSLPS-TGFACLCPDGIVPQLDG 13536
+ V + + T E CSHLC+ PS +GF+C CP GI LDG
Sbjct: 992 IHVFHR-QRPPVTTPCAVENGGCSHLCLRSPSPSGFSCTCPTGINLLLDG 1040
Score = 102 bits (255), Expect = 2e-19
Identities = 56/157 (35%), Positives = 72/157 (45%), Gaps = 5/157 (3%)
Frame = +1
Query: 520 SCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNK 699
+C R+H C + CI W CDG DC D SDE D C C+ +F C N
Sbjct: 26 ACGRSHFTC---AVSALGECTCIPAQWQCDGDNDCGDHSDE-DGCTLPTCSPLDFHCDNG 81
Query: 700 RCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGAD 879
+C R + CD +DC D+SDE +C C ++ C G+CI L CDG DC D +D
Sbjct: 82 KCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPCQ-NGYCIRSLWHCDGDNDCGDNSD 140
Query: 880 EQQCSQNLC--PSLGCQAGCHPSPH---GGECTCPSG 975
E QC C C G + H G+ C G
Sbjct: 141 E-QCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDG 176
Score = 98.6 bits (244), Expect = 4e-18
Identities = 54/195 (27%), Positives = 104/195 (52%)
Frame = +1
Query: 12952 DGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSP 13131
DG K +V +L P A++ G + ++D G +AK+E + MDG+ R +++ + + P
Sbjct: 1154 DGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTDWGENAKLERSGMDGSDRTVLINNNLGWP 1213
Query: 13132 TSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSRES 13311
+ +D+ +++ W D R++ +++G+ R T+V PY + + +++IYW ++
Sbjct: 1214 NGLTVDK-TSSQLLWADAHTERIEVADLNGANRHTLVSPVQHPYGLTLLDSYIYWTDWQT 1272
Query: 13312 KTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTG 13491
++++ DK V ++ S+L ++ + A+ G CSHLC+ PS G
Sbjct: 1273 RSIHRADKSTGSNVILVRSNLPGLMDIQAVDR-AQPLGFNKCGSRNGGCSHLCLPRPS-G 1330
Query: 13492 FACLCPDGIVPQLDG 13536
F+C CP GI + DG
Sbjct: 1331 FSCACPTGIQLKGDG 1345
Score = 94.0 bits (232), Expect = 1e-16
Identities = 57/188 (30%), Positives = 96/188 (50%), Gaps = 1/188 (0%)
Frame = +1
Query: 12952 DGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSP 13131
DG K ++ L +P A+ P G + ++D G AKIE A++DG+ R++++ + P
Sbjct: 1458 DGSCRKVLINNSLDEPRAIAVFPRKGYLFWTDWGHIAKIERANLDGSERKVLINADLGWP 1517
Query: 13132 TSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSRES 13311
+ +D RIYWVD R+++ +++G R +V P+A+ + IYW ++
Sbjct: 1518 NGLTLDYDT-RRIYWVDAHLDRIESADLNGKLRQVLVSHVSHPFALTQQDRWIYWTDWQT 1576
Query: 13312 KTLYVQDKF-GRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPST 13488
K++ DK+ GR + +VLA+ +G + + T G CSHLC + S
Sbjct: 1577 KSIQRVDKYSGRNKETVLAN--VEGLMDIIVVSPQRQTGTNACGVNNGGCSHLCFARAS- 1633
Query: 13489 GFACLCPD 13512
F C CPD
Sbjct: 1634 DFVCACPD 1641
Score = 65.1 bits (157), Expect = 5e-08
Identities = 52/201 (25%), Positives = 77/201 (37%), Gaps = 17/201 (8%)
Frame = +1
Query: 139 NTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHS 318
N +S+C FRC G+C+R W
Sbjct: 264 NCTTSMCTAEQFRCRSGRCVRLSW------------------------------------ 287
Query: 319 VSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCR 498
RCD DCAD SDE++C + + + F+C +GR C K C+G DC
Sbjct: 288 --------RCDGEDDCADNSDEENCENTGSPQCASDQFLCWNGR-CIGQRKLCNGVNDCG 338
Query: 499 DLSDE-----------KDSCSRNHTACFQ--YQFRCADKTQCIQKSWVCDGSKDCADGSD 639
D SDE +++C+ N+ C Q R A + C + + + C D ++
Sbjct: 339 DNSDESPQQNCRPRTGEENCNVNNGGCAQKCQMIRGAVQCTCHTGYRLTEDGRTCQDVNE 398
Query: 640 --EPDTCEFKKCTANE--FQC 690
E C + CT +E FQC
Sbjct: 399 CAEEGYCS-QGCTNSEGAFQC 418
Score = 63.5 bits (153), Expect = 1e-07
Identities = 67/283 (23%), Positives = 97/283 (33%), Gaps = 13/283 (4%)
Frame = +1
Query: 10753 PCGDNNGGCSH-LCLIGAGGNGYTCSCPDQFVLLSDQKTCEPN--CTERQFACGGDDAKC 10923
PC C++ C++ Y C D SD+ C + C +F C D C
Sbjct: 190 PCNLEEFQCAYGRCILDI----YHCDGDDDCGDWSDESDCSSHQPCRSGEFMC--DSGLC 243
Query: 10924 IPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXX 11103
+ W CDG+ DC D SDE C +C +F+C + C R
Sbjct: 244 VNAGWRCDGDADCDDQSDERN---CTTSMCTAEQFRCRSGRCVRLSWRCDGEDDCADNSD 300
Query: 11104 EQNCDKACDPWMFKCAA------TGRCIPRRFTXXXXXXXXXRSDEADTLCMSAERNC-- 11259
E+NC+ P +CA+ GRCI +R SDE S ++NC
Sbjct: 301 EENCENTGSP---QCASDQFLCWNGRCIGQRKLCNGVNDCGDNSDE------SPQQNCRP 351
Query: 11260 -TAEE-FRCNNNKCIAKAWRXXXXXXXXXXXXETPECAQIECKKGWTRCSSSYRCIPNWA 11433
T EE NN C K ++C C + YR +
Sbjct: 352 RTGEENCNVNNGGCAQKCQMIR---------------GAVQC-----TCHTGYRLTEDGR 391
Query: 11434 FCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMC 11562
C ++C + Q C + + C + P R C
Sbjct: 392 TCQDVNECAEEG-YCSQGCTNSEGAFQCWCEAGYELRPDRRSC 433
Score = 48.5 bits (114), Expect = 0.005
Identities = 29/106 (27%), Positives = 56/106 (52%), Gaps = 3/106 (2%)
Frame = +1
Query: 12988 LQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNR 13167
++ A+ P G++ +SD+ LH +I A +DG+ + I+ + + +A+D G +
Sbjct: 1080 MKNTIAIGVDPLEGKVYWSDSTLH-RISRASLDGSQHEDIITTGLQTTDGLAVD-AIGRK 1137
Query: 13168 IYWVDPKYRRVDAVNIDGSERTTVV-HDRHIPYAVDVFE--NHIYW 13296
+YW D R++ N+DGS R +V + P A+ ++ +YW
Sbjct: 1138 VYWTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYW 1183
Score = 38.9 bits (89), Expect = 3.7
Identities = 24/93 (25%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
Frame = +1
Query: 13027 GRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDA 13206
G++ Y+D L I AD++G++ + ++ + + +A+D N +YW D ++A
Sbjct: 1397 GKVYYTDVFLDV-IRRADLNGSNMETVIGHGLKTTDGLAVDWVARN-LYWTDTGRNTIEA 1454
Query: 13207 VNIDGSERTTVVHDR-HIPYAVDVF--ENHIYW 13296
+DGS R ++++ P A+ VF + +++W
Sbjct: 1455 SRLDGSCRKVLINNSLDEPRAIAVFPRKGYLFW 1487
>gi|47117264|sp|Q8VI56|LRP4_MOUSE Low-density lipoprotein
receptor-related protein 4 precursor (LDLR dan)
Length = 1905
Score = 681 bits (1756), Expect = 0.0
Identities = 505/1764 (28%), Positives = 812/1764 (45%), Gaps = 42/1764 (2%)
Frame = +1
Query: 3124 CQKDPAEKIEQLCSSNSTQFQCKNGR-----CIPKEWKCDGENDCLDESDEIDEKGDKCF 3288
C A +E C+ + F C CIP +W+CDG+NDC D SDE D C
Sbjct: 15 CAHGIASSLE--CACGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDE-----DGCT 67
Query: 3289 HETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNH 3468
T C+ C N K CI +D C +F C N
Sbjct: 68 LPT-CSPLDFHCDNGK-CIRRSWVCDGDNDCEDDSDE-----QDCPPRECEEDEFPCQNG 120
Query: 3469 RCIPEQWKXXXXXXXXXXXXEKLEMCGNATCAANQFSCANGRCIPIYWLCDGDNDCYDGT 3648
CI W E+ +M C+ +F C++G CI +W CDGD DC DG+
Sbjct: 121 YCIRSLWHCDGDNDCGDNSDEQCDM---RKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGS 177
Query: 3649 DEDK--ERCPPVQCSALQFRCANGRQCVPLRNHXXXXXXXXXXXXXXXXAVTAESCTPDQ 3822
DE+ P C+ +F+CA GR C+ L + + + C +
Sbjct: 178 DEESCPSAVPSPPCNLEEFQCAYGR-CI-LDIYHCDGDDDCGDWSDESDCSSHQPCRSGE 235
Query: 3823 FKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKCGNGRCILNNWLCDG 4002
F C SGLCI + W+ SDE CT+ C+++QF+C +GRC+ +W CDG
Sbjct: 236 FMC-DSGLCINSGWRCDGDADCDDQSDERN--CTTS-MCTAEQFRCRSGRCVRLSWRCDG 291
Query: 4003 ENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGG 4182
E+DC D SDE + C+ + + +C + C N + CI +LC+G C +DE
Sbjct: 292 EDDCADNSDEEN---CENT-GSPQCASDQFLCWNGR--CIGQRKLCNGINDCGDSSDESP 345
Query: 4183 ------RCARDLCSADRAGCSFKCHNSPNGPICSCPFGEQLVNKTK-CEPENECLDSSSC 4341
R + C+ + GC+ KC C+C G +L + C+ NEC + C
Sbjct: 346 QQNCRPRTGEENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTEDGRTCQDVNECAEEGYC 405
Query: 4342 SQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTF 4521
SQ C + + F C C+ GYEL D+R+CK + + +NR I +
Sbjct: 406 SQGCTNTEGAFQCWCEAGYELRPDRRSCKALG--PEPVLLFANRIDIRQVLPHRSEYTLL 463
Query: 4522 GAIVENAIALAWDSLTDRIYWSDIREKKILSANRNGTNATVFIADGLDITEGIALDWVGR 4701
+ENAIAL + + ++WSD+ +IL AN NG+N ++ GL+ G+A+DWV
Sbjct: 464 LNNLENAIALDFHHRRELVFWSDVTLDRILRANLNGSNVEEVVSTGLESPGGLAVDWVHD 523
Query: 4702 NLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQNPCIERA 4881
LYW DS + IEVANL D R +L+ Q++ +PR IA+ P +G ++WTDWG P IE +
Sbjct: 524 KLYWTDSGTSRIEVANL-DGAHRKVLLWQSLEKPRAIALHPMEGTIYWTDWGNTPRIEAS 582
Query: 4882 SMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFV 5061
SMDG+ R+II T ++WPN + +DY R+Y+ D+K I+ N DGS R V+ S+ +
Sbjct: 583 SMDGSGRRIIADTHLFWPNGLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVI--SQGL 640
Query: 5062 QHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIK 5241
HP A+ +FED +Y++D + + K+ G E + + + +HP QP K
Sbjct: 641 PHPFAITVFEDSLYWTDWHTKSINSANKF-TGKNQEIIRNKLHFPMDIHTLHPQRQPAGK 699
Query: 5242 NNPCSTN--PCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNVFGIE 5415
N C N C+HLCL + +N +TC CP G + + C FL+ ++ ++ I
Sbjct: 700 NR-CGDNNGGCTHLCLPSGQN-YTCACPTGFR-KINSHACAQSLDKFLLFARRMDIRRIS 756
Query: 5416 MNSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRS 5595
++ + ++PL+ + +A +D+ + ++ ++TD+ I R+
Sbjct: 757 FDTEDLSD-----DVIPLADVRSAVALDWDSRDDHVY----------WTDVSTDT-ISRA 800
Query: 5596 TVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVILSNDQ 5775
+G + + +++ A L DW L + T IE+ T G +I N
Sbjct: 801 KWDGTGQEVVVDTSLESPA-GLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWEN-- 857
Query: 5776 SXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAI 5955
GY++W D G A K+ RAG+D S+ VI S++L + +AI
Sbjct: 858 ----LDRPRDIVVEPMGGYMYWTDWG---ASPKIERAGMDASSRQVIISSNLTWPNGLAI 910
Query: 5956 DTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAFDSIEV 6135
D + R+Y+++A I DG R ++ P GL YG R+++ D SI+
Sbjct: 911 DYGSQRLYWADAGMKTIEFAGLDGSKRKVLIGSQLPHPFGLTLYGQRIYWTDWQTKSIQS 970
Query: 6136 A-TINGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHINNGNCDHICI----PLMF 6300
A + G + ++++ENL +I + C + NG C H+C+ P F
Sbjct: 971 ADRLTGLDRET----LQENLENLMDIHVFHRQRPPVTTLCAVENGGCSHLCLRSPNPSGF 1026
Query: 6301 AQRTCTCANG--YVKDGQTSCKLFDESFVIVATKTKV------------IGYPIDETQSK 6438
+CTC G ++DG+T C SF+I A + V + PI+ T
Sbjct: 1027 ---SCTCPTGINLLRDGKT-CSPGMNSFLIFARRIDVRMVSLDIPYFADVVVPINMTMKN 1082
Query: 6439 GVAMEPIGGLSITGVDYDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIK 6618
+A IG + G Y +S ++ AS + S +I + G T
Sbjct: 1083 TIA---IGVDPLEGKVYWSDSTLHRISRAS----------LDGSQHEDII--TTGLQTTD 1127
Query: 6619 SLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWAD 6798
LA+D I +Y+ D IEV LDG+ RK+L+ ++P +I + ++YW D
Sbjct: 1128 GLAVDAIGRKVYWT--DTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTD 1185
Query: 6799 QGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTP 6978
G+ ++RS +DGS R V++++ + P L VD S + W+DA + I G
Sbjct: 1186 WGENAKLERSGMDGSDRTVLINNNLGWPNGLTVDKTSSQLLWADAHTERIEVADLNGANR 1245
Query: 6979 ELVRSDIASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVA 7158
+ S + G+ L +YWTD + + RA +L V ++L + D+
Sbjct: 1246 HTLVSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKSTGSNVIL-----VRSNLPGLMDIQ 1300
Query: 7159 VFSSNNQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCARGV-LKG--RTCE-EPD 7326
QP + C R C+ LC P + +C+C G+ LKG +TC+ P+
Sbjct: 1301 AV-DRAQPLGFNKC----GSRNGGCSHLCLPRPSSF--SCACPTGIQLKGDRKTCDPSPE 1353
Query: 7327 TYIMFSDGDKIIDVAIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNI 7506
TY++FS I ++++ D + P P ++N+ + D D +VY+ + V +++
Sbjct: 1354 TYLLFSSRGSIRRISLDTDDHTD--VHVPVPGLNNVISLDYDSVHGKVYY---TDVFLDV 1408
Query: 7507 SWFSMNNAENPRLVFGASKQPHAKEIRHISDMKLDWLTQKIYFT-TGRGG-KVMAIDTAG 7680
+ N N V G ++ + +DW+ + +Y+T TGR + +D +
Sbjct: 1409 IRRADLNGSNMETVIGHG-------LKTTDGLAVDWVARNLYWTDTGRNTIEASRLDGSC 1461
Query: 7681 EHLSTIASGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESI 7860
+ S D A+A+ P G LFW+D G+ +IER+NL G RKV+++ +
Sbjct: 1462 RKVLINNSLDEPRAIAVFPRKGYLFWTDWGHIA-------KIERANLDGSERKVLINTDL 1514
Query: 7861 SLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGY-RAKSLDIWDRWLYMSDP 8037
P + +D+ ++IYW D + IE AD +G+ R+V+ S +L DRW+Y +D
Sbjct: 1515 GWPNGLTLDYDTRRIYWVDAHLDRIESADLNGKLRQVLVSHVSHPFALTQQDRWIYWTDW 1574
Query: 8038 LSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGC 8217
+ + R+DK SG E V+++ + G + + +T C +NGGC
Sbjct: 1575 QTKSIQRVDKYSGRNKETVLAN--VEGLMDIIVVSPQRQTGTNACG--------VNNGGC 1624
Query: 8218 DQLCTVVADDIGLAASKVQCSCND 8289
LC A D C+C D
Sbjct: 1625 THLCFARASDF-------VCACPD 1641
Score = 464 bits (1193), Expect = e-128
Identities = 320/1040 (30%), Positives = 483/1040 (45%), Gaps = 55/1040 (5%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDT-----YTWH-- 315
C+ DF C++GKCIR W P C+ D++ C WH
Sbjct: 71 CSPLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPCQNGYCIRSLWHCD 130
Query: 316 --------------------------SVSCIAEYQRCDNITDCADGSDEKDCPASTVD-- 411
SCIAE+ CD TDC DGSDE+ CP++
Sbjct: 131 GDNDCGDNSDEQCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEESCPSAVPSPP 190
Query: 412 CSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQ 591
C+ + F CA GR D+ CDG DC D SDE D CS +H C +F C D CI
Sbjct: 191 CNLEE-FQCAYGRCILDIYH-CDGDDDCGDWSDESD-CS-SHQPCRSGEFMC-DSGLCIN 245
Query: 592 KSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDEC 771
W CDG DC D SDE + C CTA +F+C++ RC +RCD DDC DNSDE+ C
Sbjct: 246 SGWRCDGDADCDDQSDERN-CTTSMCTAEQFRCRSGRCVRLSWRCDGEDDCADNSDEENC 304
Query: 772 ---GEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLG-------- 918
G +C ++ C G CI Q KLC+G DC D +DE QN P G
Sbjct: 305 ENTGSPQCASDQFLC-WNGRCIGQRKLCNGINDCGDSSDESP-QQNCRPRTGEENCNVNN 362
Query: 919 --CQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCL 1092
C C +CTC +GY+L + RTC D+NECAE GYC Q C N F C C
Sbjct: 363 GGCAQKCQMVRGAVQCTCHTGYRLTED-GRTCQDVNECAEEGYCSQGCTNTEGAFQCWCE 421
Query: 1093 GDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKLASGE 1272
G + R C + + + LF A R + ++ P E L + E
Sbjct: 422 A-----------GYELRPDRRSCKALGPEPVLLF-ANRIDIRQVLPHR-SEYTLLLNNLE 468
Query: 1273 FIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNT 1452
+DF + +FW+D A+++ S ++++ L P LAVDW+ +
Sbjct: 469 NAIALDFHHRRELVFWSDVTLDRILRANLNG----SNVEEVVSTGLESPGGLAVDWVHDK 524
Query: 1453 LYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFT---NQLKLEAAAM 1623
LY +SG+ RI+V++ DG R VLL L P IAL P+ G +++T N ++EA++M
Sbjct: 525 LYWTDSGTSRIEVANLDGAHRKVLLWQSLEKPRAIALHPMEGTIYWTDWGNTPRIEASSM 584
Query: 1624 DGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRR-IVAQGMNVVP 1800
DG+ RR + +TH +G+ +D +R+YWVD K +E + G+ R+ +++QG+ P
Sbjct: 585 DGSGRRIIADTHLFWPNGLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVISQGL---P 641
Query: 1801 HPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPG 1980
HPF + +F+ LYWTDW + KF + + N + FPM I HP QP G
Sbjct: 642 HPFAITVFEDSLYWTDWHTKSINSANKFTGKNQEIIRNKLH--FPMDIHTLHPQRQPA-G 698
Query: 1981 QSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGKRCIDSID-YLL 2157
++ C N C +C+ S G Y CACP G + +N C S+D +LL
Sbjct: 699 KNRC-------GDNNGGCTHLCLPS------GQNYTCACPTGFRKINSHACAQSLDKFLL 745
Query: 2158 FSSNKIVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIY 2337
F+ +R I + + L++ V+P++ + ++ D + ++ D+ +TI
Sbjct: 746 FARRMDIRRI--SFDTEDLSDDVIPLADVRSA-----VALDWDSRDDHVYWTDVSTDTIS 798
Query: 2338 RIRPDGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVR 2517
R + DG G V+ T + ++ DW++ +LY+ D + +EV + D +R
Sbjct: 799 RAKWDGTGQEVVVDTSLESPAGLAIDWVTNKLYWTDAGTDRIEV--------ANTDGSMR 850
Query: 2518 RQLITELRD-PVSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAI 2694
LI E D P +VV P G +++ + I R +D + QVI ++ L P+ +AI
Sbjct: 851 TVLIWENLDRPRDIVVEPMGGYMYWTDWGASPKIERAGMDASSRQVIISSNLTWPNGLAI 910
Query: 2695 DFAENRLCWGDTLLKTISCMDFDG-KNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRR 2871
D+ RL W D +KTI DG K V + P P +T+ + IY+ + SI+
Sbjct: 911 DYGSQRLYWADAGMKTIEFAGLDGSKRKVLIGSQLPHPFGLTLYGQRIYWTDWQTKSIQS 970
Query: 2872 VHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSES 3051
+ G + ++E + ++ + Q P+ + C+ LC +P+ S
Sbjct: 971 ADRLTGLDRETLQE---NLENLMDIHVFHRQRPPV---TTLCAVENGGCSHLCLRSPNPS 1024
Query: 3052 HPNELEAKCACRQGFMINKE 3111
C C G + ++
Sbjct: 1025 -----GFSCTCPTGINLLRD 1039
Score = 458 bits (1178), Expect = e-126
Identities = 273/769 (35%), Positives = 387/769 (49%), Gaps = 13/769 (1%)
Frame = +1
Query: 8575 CGDG-SDELDCPSAVACAEGTFPCSNGH-----CINQTKVCDGHNDCHDEQVSDESLATC 8736
C G + L+C AC F C+ CI CDG NDC D SDE T
Sbjct: 15 CAHGIASSLEC----ACGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDH--SDEDGCTL 68
Query: 8737 PGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGR 8916
P C + C N CI+ + +CDG +DC D +DE C ++C + C +G
Sbjct: 69 P----TCSPLDFHCDNGK-CIRRSWVCDGDNDCEDDSDEQD--CPPRECEEDEFPCQNGY 121
Query: 8917 CIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXX 9096
CI W CDGDNDC D DE + C D F+C + CI+ +
Sbjct: 122 CIRSLWHCDGDNDCGDNSDEQ-------CDMRKC-SDKEFRCSDGSCIAEHWYCDGDTDC 173
Query: 9097 XXXXXXHS-RHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTE 9273
S + C +EF C CI + CDGD C DES
Sbjct: 174 KDGSDEESCPSAVPSPPCNLEEFQCAYG--------RCILDIYHCDGDDDCGDWSDESD- 224
Query: 9274 LCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCANHK 9453
C + + C GEF C + CI+S W CDGD DC D SDE NCT S C + F+C + +
Sbjct: 225 -CSSHQP-CRSGEFMCDSGLCINSGWRCDGDADCDDQSDER-NCTTSMCTAEQFRCRSGR 281
Query: 9454 CVPNSWKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFD 9633
CV SW+CDG DDC D SDE++C +N+ S Q C++ QF C +G CI K+C+ D
Sbjct: 282 CVRLSWRCDGEDDCADNSDEENC-ENTGSPQ----CASDQFLCWNGRCIGQRKLCNGIND 336
Query: 9634 CTDRSDESSLCFI------DECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCH 9795
C D SDES + C++ C QKC ++ +C C G+ + D ++C
Sbjct: 337 CGDSSDESPQQNCRPRTGEENCNVNNGG-CAQKCQMVRGAVQCTCHTGYRLT-EDGRTCQ 394
Query: 9796 NVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIR 9975
+VNEC E CSQ C + G+++C C GY+L D SCK + PEP L AN+ IR
Sbjct: 395 DVNECAEE-GYCSQGCTNTEGAFQCWCEAGYELRPDRRSCKA--LGPEPVLLFANRIDIR 451
Query: 9976 KISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVL 10155
++ ++Y L +N ++LD + + D R+LR +L+ S+ E V+
Sbjct: 452 QVLPHRSEYTLLLNNLENAIALDFHHRRELVFWSDVTLDRILRANLNG-----SNVEEVV 506
Query: 10156 RHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKG 10335
+ G+AVDWV KLY + I V LDG K L+ +++P+AI +HP +G
Sbjct: 507 STGLESPGGLAVDWVHDKLYWTDSGTSRIEVANLDGAHRKVLLWQSLEKPRAIALHPMEG 566
Query: 10336 YLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNE 10515
+++T+W P I ++DGS +A+ L WPN + IDY R++W DA +
Sbjct: 567 TIYWTDWGNTPRIEASSMDGSGRRI-----IADTHLFWPNGLTIDYAGRRMYWVDAKHHV 621
Query: 10516 IGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTV 10695
I + DG+ R+ + +Q H ++ VF+D LYW DW+ + + +K+TGKN+ I++ +
Sbjct: 622 IERANLDGSHRKAVISQGLPHPFAITVFEDSLYWTDWHTKSINSANKFTGKNQEIIRNKL 681
Query: 10696 QLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQF 10842
P D+ +HP RQPA N CGDNNGGC+HLCL G YTC+CP F
Sbjct: 682 HFPMDIHTLHPQRQPAGKNRCGDNNGGCTHLCL--PSGQNYTCACPTGF 728
Score = 329 bits (844), Expect = 1e-87
Identities = 238/776 (30%), Positives = 341/776 (43%), Gaps = 47/776 (6%)
Frame = +1
Query: 11359 ECAQIECKKGWTRCSSSY----RCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCA 11526
ECA C + C+ S CIP C+G +DC D+SDED PTC + +F C
Sbjct: 24 ECA---CGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDEDGCTLPTCSPL-DFHC- 78
Query: 11527 TSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQ 11706
+GKCI R W+CD +NDC D+SDE D R C E EF C +G CI CDG
Sbjct: 79 DNGKCIRRSWVCDGDNDCEDDSDEQDCP----PRECEEDEFPCQNGYCIRSLWHCDGDND 134
Query: 11707 CSDGLDESQCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCED-VSRRTCSP 11883
C D DE QC +R+C +C DG+CIAEH +CD DC + +DE C V C+
Sbjct: 135 CGDNSDE-QCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEESCPSAVPSPPCNL 193
Query: 11884 FEFECANSVCIPRKFMXXXXXXXXXXSDETSSE----CRSAQ--CDPPL----------- 12012
EF+CA CI + SDE+ CRS + CD L
Sbjct: 194 EEFQCAYGRCILDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMCDSGLCINSGWRCDGD 253
Query: 12013 --------------------RFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSFS 12132
+FRC R C+ + C+G +DC N SDE C +
Sbjct: 254 ADCDDQSDERNCTTSMCTAEQFRCRSGR-CVRLSWRCDGEDDCADN--SDEE--NCENTG 308
Query: 12133 EYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEI---GCSKHGGKTSCEAFGNNGGC 12303
C+SDQF C NG+C+ C+ +DCGD+SDE C G+ +C NNGGC
Sbjct: 309 S-PQCASDQFLCWNGRCIGQRKLCNGINDCGDSSDESPQQNCRPRTGEENCNV--NNGGC 365
Query: 12304 KHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGSYLCRCHEDY 12483
C VR C C G+R + + C D++ECA C+Q C NT+G++ C C Y
Sbjct: 366 AQKCQMVRGAVQCTCHTGYRLT-EDGRTCQDVNECAEEGYCSQGCTNTEGAFQCWCEAGY 424
Query: 12484 ENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXX 12663
E + C+A G ++ + Q+ H R
Sbjct: 425 ELR-----PDRRSCKALGPEPVLLFANRIDIRQVLPH-----RSEYTLLLNNLENAIALD 474
Query: 12664 XXPRKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFI 12843
R+EL++W S+ T+ R AN N S+ + + + P +AVD+ L+
Sbjct: 475 FHHRRELVFW---SDVTLDRILRANLNGSNVEEVVSTGLES----PGGLAVDWVHDKLYW 527
Query: 12844 AAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPS 13023
+ T I V DG + K ++ L++P A+ P
Sbjct: 528 T-----------------------DSGTSRIEVANLDGAHRKVLLWQSLEKPRAIALHPM 564
Query: 13024 AGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVD 13203
G I ++D G +IE + MDG+ R+II +F P + ID G R+YWVD K+ ++
Sbjct: 565 EGTIYWTDWGNTPRIEASSMDGSGRRIIADTHLFWPNGLTIDYA-GRRMYWVDAKHHVIE 623
Query: 13204 AVNIDGSERTTVV-HDRHIPYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLED 13380
N+DGS R V+ P+A+ VFE+ +YW +K++ +KF ++ + L
Sbjct: 624 RANLDGSHRKAVISQGLPHPFAITVFEDSLYWTDWHTKSINSANKFTGKNQEIIRNKLHF 683
Query: 13381 GHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPS-TGFACLCPDGIVPQLDGSCA 13545
+ + + G C+HLC LPS + C CP G +CA
Sbjct: 684 PMDIHTLHPQRQPAGKNRCGDNNGGCTHLC--LPSGQNYTCACPTGFRKINSHACA 737
Score = 243 bits (619), Expect = 1e-61
Identities = 197/730 (26%), Positives = 335/730 (44%), Gaps = 10/730 (1%)
Frame = +1
Query: 1018 NECAEF-GYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLF 1194
N C + G C LC +TC+C G K N + + + DK LF
Sbjct: 700 NRCGDNNGGCTHLCLPSGQNYTCAC---------PTGFRKIN----SHACAQSLDKFLLF 746
Query: 1195 VARREGLYRLNPKNPD--EEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDE 1368
ARR + R++ D ++V LA +D+D D ++WTD + A D
Sbjct: 747 -ARRMDIRRISFDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDGT 805
Query: 1369 GEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLP 1548
G+ + SL+S P LA+DW+TN LY ++G+ RI+V++ DG RTVL+ + L P
Sbjct: 806 GQ-EVVVDTSLES---PAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRP 861
Query: 1549 LDIALDPLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVD 1719
DI ++P+ G M++T+ K+E A MD ++R+ +++++ +G+ +D ++R+YW D
Sbjct: 862 RDIVVEPMGGYMYWTDWGASPKIERAGMDASSRQVIISSNLTWPNGLAIDYGSQRLYWAD 921
Query: 1720 PKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKF-GSDT 1896
+ +E G+ R+++ +PHPFGL L+ Q +YWTDW + ++ G D
Sbjct: 922 AGMKTIEFAGLDGSKRKVLIGSQ--LPHPFGLTLYGQRIYWTDWQTKSIQSADRLTGLDR 979
Query: 1897 KLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFG 2076
+ L N EN M I +H Q P + C N C +C+ S + GF
Sbjct: 980 ETLQENLEN---LMDIHVFH--RQRPPVTTLCAV-------ENGGCSHLCLRSPNPSGF- 1026
Query: 2077 VGYKCACPIGQKLV-NGKRCIDSID-YLLFSSNKIVRGIFPEINEKALAEAVLPISPISQ 2250
C CP G L+ +GK C ++ +L+F+ VR + +I A+ V+PI+ +
Sbjct: 1027 ---SCTCPTGINLLRDGKTCSPGMNSFLIFARRIDVRMVSLDI--PYFADVVVPINMTMK 1081
Query: 2251 RRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWISKQ 2430
I + D +++D + I R DG ++ T ++ D I ++
Sbjct: 1082 NTIA----IGVDPLEGKVYWSDSTLHRISRASLDGSQHEDIITTGLQTTDGLAVDAIGRK 1137
Query: 2431 LYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITE-LRDPVSVVVHPWKGLLFYAEAMRP 2607
+Y+ D N +EV + D +R+ L+ + L P ++V++ G +++ +
Sbjct: 1138 VYWTDTGTNRIEVGNL--------DGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTDWGEN 1189
Query: 2608 AAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVKLD 2787
A + R +DG + V+ N LG P+ + +D ++L W D + I D +G N L
Sbjct: 1190 AKLERSGMDGSDRTVLINNNLGWPNGLTVDKTSSQLLWADAHTERIEVADLNGANRHTLV 1249
Query: 2788 IDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQN 2967
P +T+++ YIY+ + SI R K G +VR ++ L +
Sbjct: 1250 SPVQHPYGLTLLDSYIYWTDWQTRSIHRADKSTGSNVILVRS------NLPGLMDIQAVD 1303
Query: 2968 QPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINKENNHSCQKDPAEK 3147
+ P + R C+ LC PS CAC G + K + +C DP+ +
Sbjct: 1304 RAQPLGFNKCGSRNGGCSHLCLPRPS-------SFSCACPTGIQL-KGDRKTC--DPSPE 1353
Query: 3148 IEQLCSSNST 3177
L SS +
Sbjct: 1354 TYLLFSSRGS 1363
Score = 232 bits (591), Expect = 2e-58
Identities = 128/349 (36%), Positives = 186/349 (52%), Gaps = 3/349 (0%)
Frame = +1
Query: 9802 NECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKI 9981
N+C GCS C + S+ C C G QL D +C + PE + L +++ IR+I
Sbjct: 1311 NKCGSRNGGCSHLCLPRPSSFSCACPTGIQLKGDRKTC---DPSPETYLLFSSRGSIRRI 1367
Query: 9982 SIDGNKY---ELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETV 10152
S+D + + + G +NV+SLD D K Y D + R DL+ S+ ETV
Sbjct: 1368 SLDTDDHTDVHVPVPGLNNVISLDYDSVHGKVYYTDVFLDVIRRADLNG-----SNMETV 1422
Query: 10153 LRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGK 10332
+ H + T+G+AVDWV R LY + +I LDG K LI + + +P+AI V P K
Sbjct: 1423 IGHGLKTTDGLAVDWVARNLYWTDTGRNTIEASRLDGSCRKVLINNSLDEPRAIAVFPRK 1482
Query: 10333 GYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLN 10512
GYLF+T+W I R LDGS L DLGWPN + +DY + R++W DAHL+
Sbjct: 1483 GYLFWTDWGHIAKIERANLDGSERK-----VLINTDLGWPNGLTLDYDTRRIYWVDAHLD 1537
Query: 10513 EIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKT 10692
I D +G R + SH ++ D ++YW DW + + R DK++G+N+ +
Sbjct: 1538 RIESADLNGK-LRQVLVSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVLAN 1596
Query: 10693 VQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQ 10839
V+ D+ +V P RQ N CG NNGGC+HLC A + + C+CPD+
Sbjct: 1597 VEGLMDIIVVSPQRQTG-TNACGVNNGGCTHLCF--ARASDFVCACPDE 1642
Score = 223 bits (567), Expect = 1e-55
Identities = 205/737 (27%), Positives = 325/737 (43%), Gaps = 22/737 (2%)
Frame = +1
Query: 994 FHRTCSDINE-CA-EFGYCDQLCAN--HRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYC 1161
FHR + CA E G C LC + GF+C+C P NL G
Sbjct: 995 FHRQRPPVTTLCAVENGGCSHLCLRSPNPSGFSCTC------------PTGINLLRDGKT 1042
Query: 1162 VSNNADKMKLFVARREGLYRLN---PKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRL 1332
S + +F ARR + ++ P D V + + I D + K++W+D
Sbjct: 1043 CSPGMNSFLIF-ARRIDVRMVSLDIPYFADVVVPINMTMKNTIAIGVDPLEGKVYWSDST 1101
Query: 1333 AHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGER 1512
H A +D SQ + + L LAVD I +Y ++G+ RI+V + DG
Sbjct: 1102 LHRISRASLDG----SQHEDIITTGLQTTDGLAVDAIGRKVYWTDTGTNRIEVGNLDGSM 1157
Query: 1513 RTVLLADGLTLPLDIALDPLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHTHQVSGIV 1683
R VL+ L P I L G M++T+ KLE + MDG++R L+N + +G+
Sbjct: 1158 RKVLVWQNLDSPRAIVLYHEMGFMYWTDWGENAKLERSGMDGSDRTVLINNNLGWPNGLT 1217
Query: 1684 VDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLG 1863
VD T+ ++ W D +R+E D G +R + ++ V HP+GL L D Y+YWTDW
Sbjct: 1218 VDKTSSQLLWADAHTERIEVADLNGANRHTL---VSPVQHPYGLTLLDSYIYWTDWQTRS 1274
Query: 1864 VIQVEKF-GSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEG 2040
+ + +K GS+ L+ SN + + P+ G ++C + N C
Sbjct: 1275 IHRADKSTGSNVILVRSNLPGLMDIQAVDRAQPL-----GFNKCGSR-------NGGCSH 1322
Query: 2041 MCILSKDNGGFGVGYKCACPIGQKLVNGKRCIDSID--YLLFSSNKIVRGIFPEINEKAL 2214
+C+ + + CACP G +L ++ D YLLFSS +R I + ++
Sbjct: 1323 LCLPRPSS------FSCACPTGIQLKGDRKTCDPSPETYLLFSSRGSIRRISLDTDDHTD 1376
Query: 2215 AEAVLPISPISQRRIGMYFEVECD---VHGNSFFYADIMDNTIYRIRPDGEGAAPVL--- 2376
+P G+ + D VHG +Y D+ + I R +G V+
Sbjct: 1377 VHVPVP---------GLNNVISLDYDSVHGK-VYYTDVFLDVIRRADLNGSNMETVIGHG 1426
Query: 2377 VTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITE-LRDPVS 2553
+ DGL + DW+++ LY+ D RN++E ++ D R+ LI L +P +
Sbjct: 1427 LKTTDGL---AVDWVARNLYWTDTGRNTIEASRL--------DGSCRKVLINNSLDEPRA 1475
Query: 2554 VVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTL 2733
+ V P KG LF+ + A I R ++DG +V+ NT LG P+ + +D+ R+ W D
Sbjct: 1476 IAVFPRKGYLFWTDWGHIAKIERANLDGSERKVLINTDLGWPNGLTLDYDTRRIYWVDAH 1535
Query: 2734 LKTISCMDFDGKNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVRE 2913
L I D +GK L P A+T + +IY+ + SI+RV K +G + V
Sbjct: 1536 LDRIESADLNGKLRQVLVSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVL- 1594
Query: 2914 FGADERSIFSLKACSHQNQPIPDDSREHPCRASQ--CTQLCFATPSESHPNELEAKCACR 3087
A+ + + S Q Q + + C + CT LCFA S + CAC
Sbjct: 1595 --ANVEGLMDIIVVSPQRQ-----TGTNACGVNNGGCTHLCFARAS-------DFVCACP 1640
Query: 3088 QGFMINKENNHSCQKDP 3138
++ + H C P
Sbjct: 1641 -----DEPDGHPCSLVP 1652
Score = 194 bits (492), Expect = 7e-47
Identities = 110/361 (30%), Positives = 170/361 (46%), Gaps = 3/361 (0%)
Frame = +1
Query: 9802 NECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKI 9981
N C + GC+ C +Y C C G++ + H+C ++ + F L A + IR+I
Sbjct: 700 NRCGDNNGGCTHLCLPSGQNYTCACPTGFR-KINSHACAQSL---DKFLLFARRMDIRRI 755
Query: 9982 SIDGNKYE---LAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETV 10152
S D + + V+LD D + Y D + R D + E V
Sbjct: 756 SFDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDG-----TGQEVV 810
Query: 10153 LRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGK 10332
+ ++ G+A+DWV KLY + I V DG LI + + +P+ IVV P
Sbjct: 811 VDTSLESPAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRPRDIVVEPMG 870
Query: 10333 GYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLN 10512
GY+++T+W P I R +D S + +L WPN +AIDY S RL+W DA +
Sbjct: 871 GYMYWTDWGASPKIERAGMDASSRQV-----IISSNLTWPNGLAIDYGSQRLYWADAGMK 925
Query: 10513 EIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKT 10692
I F DG+ R+ + + H + ++ +YW DW + + D+ TG + L++
Sbjct: 926 TIEFAGLDGSKRKVLIGSQLPHPFGLTLYGQRIYWTDWQTKSIQSADRLTGLDRETLQEN 985
Query: 10693 VQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTCE 10872
++ D+ + H R P C NGGCSHLCL +G++C+CP LL D KTC
Sbjct: 986 LENLMDIHVFHRQRPPV-TTLCAVENGGCSHLCLRSPNPSGFSCTCPTGINLLRDGKTCS 1044
Query: 10873 P 10875
P
Sbjct: 1045 P 1045
Score = 191 bits (484), Expect = 6e-46
Identities = 111/357 (31%), Positives = 169/357 (47%), Gaps = 6/357 (1%)
Frame = +1
Query: 9826 GCSQKC--DDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNK 9999
GCS C + C C G L D +C F + A + +R +S+D
Sbjct: 1012 GCSHLCLRSPNPSGFSCTCPTGINLLRDGKTCSPGM---NSFLIFARRIDVRMVSLDIPY 1068
Query: 10000 YELAAQGFD----NVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNV 10167
+ + N +++ +D E K Y D R+ R LD S +E ++ +
Sbjct: 1069 FADVVVPINMTMKNTIAIGVDPLEGKVYWSDSTLHRISRASLDG-----SQHEDIITTGL 1123
Query: 10168 YGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFF 10347
T+G+AVD +GRK+Y + I V LDG K L+ + P+AIV++ G++++
Sbjct: 1124 QTTDGLAVDAIGRKVYWTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYW 1183
Query: 10348 TEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFM 10527
T+W + R +DGS L ++LGWPN + +D S +L W DAH I
Sbjct: 1184 TDWGENAKLERSGMDGSDRT-----VLINNNLGWPNGLTVDKTSSQLLWADAHTERIEVA 1238
Query: 10528 DFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPN 10707
D +G RH H + + D Y+YW DW R + R DK TG N +++ +
Sbjct: 1239 DLNG-ANRHTLVSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKSTGSNVILVRSNLPGLM 1297
Query: 10708 DLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTCEPN 10878
D++ V QP N CG NGGCSHLCL + ++C+CP L D+KTC+P+
Sbjct: 1298 DIQAV-DRAQPLGFNKCGSRNGGCSHLCL--PRPSSFSCACPTGIQLKGDRKTCDPS 1351
Score = 159 bits (402), Expect = 2e-36
Identities = 104/319 (32%), Positives = 141/319 (43%), Gaps = 3/319 (0%)
Frame = +1
Query: 8383 PYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCN 8562
P +F C +G CI CD DC D SDE C R C ED C N CI S C+
Sbjct: 73 PLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQD--CPPRECEEDEFPCQNGYCIRSLWHCD 130
Query: 8563 HIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPG 8742
+DCGD SDE C C++ F CS+G CI + CDG DC D + + P
Sbjct: 131 GDNDCGDNSDE-QCDMR-KCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEESCPSAVPS 188
Query: 8743 LPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCI 8922
P C + +C CI CDG DDCGD +DE+ +Q C C SG CI
Sbjct: 189 PP--CNLEEFQCAYGR-CILDIYHCDGDDDCGDWSDESDC-SSHQPCRSGEFMCDSGLCI 244
Query: 8923 PETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXX 9102
W+CDGD DC D DE NCT + +C + F+C + +C+ ++
Sbjct: 245 NSGWRCDGDADCDDQSDE--RNCTTS----MCTAEQ-FRCRSGRCVRLSWRCDGEDDCAD 297
Query: 9103 XXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTEL-C 9279
+ G+ C +F C + CI + LC+G C DES + C
Sbjct: 298 NSDEENCENTGSPQCASDQFLCWNG--------RCIGQRKLCNGINDCGDSSDESPQQNC 349
Query: 9280 --KTEKKECNKGEFRCSNQ 9330
+T ++ CN C+ +
Sbjct: 350 RPRTGEENCNVNNGGCAQK 368
Score = 150 bits (379), Expect = 9e-34
Identities = 112/340 (32%), Positives = 147/340 (42%), Gaps = 10/340 (2%)
Frame = +1
Query: 8362 PAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCI 8541
P +EC F C +G CI CD DC D SDE C+ R C + C++ CI
Sbjct: 106 PPRECEED-EFPCQNGYCIRSLWHCDGDNDCGDNSDEQ---CDMRKCSDKEFRCSDGSCI 161
Query: 8542 DSAKKCNHIDDCGDGSDELDCPSAV---ACAEGTFPCSNGHCINQTKVCDGHNDCHDEQV 8712
C+ DC DGSDE CPSAV C F C+ G CI CDG +DC D
Sbjct: 162 AEHWYCDGDTDCKDGSDEESCPSAVPSPPCNLEEFQCAYGRCILDIYHCDGDDDCGD--W 219
Query: 8713 SDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQH 8892
SDES + CR + C ++ +CI CDG DC D++DE C C
Sbjct: 220 SDESDCSSHQ---PCRSGEFMC-DSGLCINSGWRCDGDADCDDQSDERN--CTTSMCTAE 273
Query: 8893 YVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAF 9072
RC SGRC+ +W+CDG++DC+D DE NC +T G C D F C N +CI +
Sbjct: 274 QFRCRSGRCVRLSWRCDGEDDCADNSDE--ENCENT-GSPQCASDQ-FLCWNGRCIGQRK 329
Query: 9073 IXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAG 9252
+ + C RT E +C N K + + A C TC
Sbjct: 330 LCNGINDCGDSSDESPQQNCRPRT---GEENCNVNNGGCAQKCQMVRGAVQC----TCHT 382
Query: 9253 GE--DESTELCK-----TEKKECNKGEFRCSNQHCIHSTW 9351
G E C+ E+ C++G C+N W
Sbjct: 383 GYRLTEDGRTCQDVNECAEEGYCSQG---CTNTEGAFQCW 419
Score = 131 bits (330), Expect = 4e-28
Identities = 99/313 (31%), Positives = 128/313 (40%), Gaps = 7/313 (2%)
Frame = +1
Query: 11590 SDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQ 11769
+ L+ +CG + C+ S + CIP CDG C D DE CTL C P
Sbjct: 20 ASSLECACGRSHFTCAVSAL--GECTCIPAQWQCDGDNDCGDHSDEDGCTLPTCSPLDFH 77
Query: 11770 CDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFECANSVCIPRKFMXXXXXX 11949
CD+G CI CD DC + +DE C R C EF C N CI +
Sbjct: 78 CDNGKCIRRSWVCDGDNDCEDDSDEQDCPP---RECEEDEFPCQNGYCIRSLWHCDGDND 134
Query: 11950 XXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSF 12129
SDE +C +C FRC+ C+ C+G DC D SDE C S
Sbjct: 135 CGDNSDE---QCDMRKCSDK-EFRCSDGS-CIAEHWYCDGDTDC--KDGSDEE--SCPSA 185
Query: 12130 SEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKH 12309
C+ ++F+CA G+C+ CD DDCGD SDE CS H S E ++G C
Sbjct: 186 VPSPPCNLEEFQCAYGRCILDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMCDSGLC-- 243
Query: 12310 ICTDVRDGFYCHCRDGFRP-DPQSPKECIDIDECAG------NNTCTQLCLNTKGSYLCR 12468
+ G+ C DG D QS + C + C +L G C
Sbjct: 244 ----INSGWRC---DGDADCDDQSDERNCTTSMCTAEQFRCRSGRCVRLSWRCDGEDDCA 296
Query: 12469 CHEDYENNVVVGS 12507
+ D EN GS
Sbjct: 297 DNSDEENCENTGS 309
Score = 106 bits (265), Expect = 1e-20
Identities = 77/290 (26%), Positives = 130/290 (44%), Gaps = 2/290 (0%)
Frame = +1
Query: 12673 RKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAV 12852
R + +YW D S TI R+ GQ++ VD + P +A+D+ T L+
Sbjct: 783 RDDHVYWTDVSTDTISRA-----KWDGTGQEVVVDTSLES--PAGLAIDWVTNKLYWT-- 833
Query: 12853 SENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGR 13032
+ T I V DG ++ +L +P ++ P G
Sbjct: 834 ---------------------DAGTDRIEVANTDGSMRTVLIWENLDRPRDIVVEPMGGY 872
Query: 13033 ICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVN 13212
+ ++D G KIE A MD + RQ+I+ + P +AID G R+YW D + ++
Sbjct: 873 MYWTDWGASPKIERAGMDASSRQVIISSNLTWPNGLAIDYG-SQRLYWADAGMKTIEFAG 931
Query: 13213 IDGSERTTVVHDR-HIPYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHT 13389
+DGS+R ++ + P+ + ++ IYW ++K++ D+ L +LE+
Sbjct: 932 LDGSKRKVLIGSQLPHPFGLTLYGQRIYWTDWQTKSIQSADRLTGLDRETLQENLENLMD 991
Query: 13390 VRVSQKYAKDTQRTVSGCERAQCSHLCVSLPS-TGFACLCPDGIVPQLDG 13536
+ V + + T+ E CSHLC+ P+ +GF+C CP GI DG
Sbjct: 992 IHVFHR-QRPPVTTLCAVENGGCSHLCLRSPNPSGFSCTCPTGINLLRDG 1040
Score = 102 bits (255), Expect = 2e-19
Identities = 56/157 (35%), Positives = 72/157 (45%), Gaps = 5/157 (3%)
Frame = +1
Query: 520 SCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNK 699
+C R+H C + CI W CDG DC D SDE D C C+ +F C N
Sbjct: 26 ACGRSHFTC---AVSALGECTCIPAQWQCDGDNDCGDHSDE-DGCTLPTCSPLDFHCDNG 81
Query: 700 RCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGAD 879
+C R + CD +DC D+SDE +C C ++ C G+CI L CDG DC D +D
Sbjct: 82 KCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPCQ-NGYCIRSLWHCDGDNDCGDNSD 140
Query: 880 EQQCSQNLC--PSLGCQAGCHPSPH---GGECTCPSG 975
E QC C C G + H G+ C G
Sbjct: 141 E-QCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDG 176
Score = 95.9 bits (237), Expect = 3e-17
Identities = 55/199 (27%), Positives = 105/199 (52%)
Frame = +1
Query: 12952 DGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSP 13131
DG K +V +L P A++ G + ++D G +AK+E + MDG+ R +++ + + P
Sbjct: 1154 DGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTDWGENAKLERSGMDGSDRTVLINNNLGWP 1213
Query: 13132 TSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSRES 13311
+ +D+ +++ W D R++ +++G+ R T+V PY + + +++IYW ++
Sbjct: 1214 NGLTVDK-TSSQLLWADAHTERIEVADLNGANRHTLVSPVQHPYGLTLLDSYIYWTDWQT 1272
Query: 13312 KTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTG 13491
++++ DK V ++ S+L ++ + A+ G CSHLC+ PS+
Sbjct: 1273 RSIHRADKSTGSNVILVRSNLPGLMDIQAVDR-AQPLGFNKCGSRNGGCSHLCLPRPSS- 1330
Query: 13492 FACLCPDGIVPQLDGSCAT 13548
F+C CP GI QL G T
Sbjct: 1331 FSCACPTGI--QLKGDRKT 1347
Score = 93.2 bits (230), Expect = 2e-16
Identities = 56/188 (29%), Positives = 96/188 (50%), Gaps = 1/188 (0%)
Frame = +1
Query: 12952 DGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSP 13131
DG K ++ L +P A+ P G + ++D G AKIE A++DG+ R++++ + P
Sbjct: 1458 DGSCRKVLINNSLDEPRAIAVFPRKGYLFWTDWGHIAKIERANLDGSERKVLINTDLGWP 1517
Query: 13132 TSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSRES 13311
+ +D RIYWVD R+++ +++G R +V P+A+ + IYW ++
Sbjct: 1518 NGLTLDYDT-RRIYWVDAHLDRIESADLNGKLRQVLVSHVSHPFALTQQDRWIYWTDWQT 1576
Query: 13312 KTLYVQDKF-GRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPST 13488
K++ DK+ GR + +VLA+ +G + + T G C+HLC + S
Sbjct: 1577 KSIQRVDKYSGRNKETVLAN--VEGLMDIIVVSPQRQTGTNACGVNNGGCTHLCFARAS- 1633
Query: 13489 GFACLCPD 13512
F C CPD
Sbjct: 1634 DFVCACPD 1641
Score = 64.3 bits (155), Expect = 8e-08
Identities = 52/201 (25%), Positives = 76/201 (36%), Gaps = 17/201 (8%)
Frame = +1
Query: 139 NTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHS 318
N +S+C FRC G+C+R W
Sbjct: 264 NCTTSMCTAEQFRCRSGRCVRLSW------------------------------------ 287
Query: 319 VSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCR 498
RCD DCAD SDE++C + + + F+C +GR C K C+G DC
Sbjct: 288 --------RCDGEDDCADNSDEENCENTGSPQCASDQFLCWNGR-CIGQRKLCNGINDCG 338
Query: 499 DLSDE-----------KDSCSRNHTACFQ--YQFRCADKTQCIQKSWVCDGSKDCADGSD 639
D SDE +++C+ N+ C Q R A + C + + + C D ++
Sbjct: 339 DSSDESPQQNCRPRTGEENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTEDGRTCQDVNE 398
Query: 640 --EPDTCEFKKCTANE--FQC 690
E C + CT E FQC
Sbjct: 399 CAEEGYCS-QGCTNTEGAFQC 418
Score = 63.9 bits (154), Expect = 1e-07
Identities = 68/283 (24%), Positives = 97/283 (34%), Gaps = 13/283 (4%)
Frame = +1
Query: 10753 PCGDNNGGCSH-LCLIGAGGNGYTCSCPDQFVLLSDQKTCEPN--CTERQFACGGDDAKC 10923
PC C++ C++ Y C D SD+ C + C +F C D C
Sbjct: 190 PCNLEEFQCAYGRCILDI----YHCDGDDDCGDWSDESDCSSHQPCRSGEFMC--DSGLC 243
Query: 10924 IPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXX 11103
I W CDG+ DC D SDE C +C +F+C + C R
Sbjct: 244 INSGWRCDGDADCDDQSDERN---CTTSMCTAEQFRCRSGRCVRLSWRCDGEDDCADNSD 300
Query: 11104 EQNCDKACDPWMFKCAA------TGRCIPRRFTXXXXXXXXXRSDEADTLCMSAERNC-- 11259
E+NC+ P +CA+ GRCI +R SDE S ++NC
Sbjct: 301 EENCENTGSP---QCASDQFLCWNGRCIGQRKLCNGINDCGDSSDE------SPQQNCRP 351
Query: 11260 -TAEE-FRCNNNKCIAKAWRXXXXXXXXXXXXETPECAQIECKKGWTRCSSSYRCIPNWA 11433
T EE NN C K ++C C + YR +
Sbjct: 352 RTGEENCNVNNGGCAQKCQMVR---------------GAVQC-----TCHTGYRLTEDGR 391
Query: 11434 FCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMC 11562
C ++C + Q C + + C + P R C
Sbjct: 392 TCQDVNECAEEG-YCSQGCTNTEGAFQCWCEAGYELRPDRRSC 433
Score = 48.5 bits (114), Expect = 0.005
Identities = 29/106 (27%), Positives = 56/106 (52%), Gaps = 3/106 (2%)
Frame = +1
Query: 12988 LQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNR 13167
++ A+ P G++ +SD+ LH +I A +DG+ + I+ + + +A+D G +
Sbjct: 1080 MKNTIAIGVDPLEGKVYWSDSTLH-RISRASLDGSQHEDIITTGLQTTDGLAVD-AIGRK 1137
Query: 13168 IYWVDPKYRRVDAVNIDGSERTTVV-HDRHIPYAVDVFE--NHIYW 13296
+YW D R++ N+DGS R +V + P A+ ++ +YW
Sbjct: 1138 VYWTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYW 1183
Score = 38.9 bits (89), Expect = 3.7
Identities = 24/93 (25%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
Frame = +1
Query: 13027 GRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDA 13206
G++ Y+D L I AD++G++ + ++ + + +A+D N +YW D ++A
Sbjct: 1397 GKVYYTDVFLDV-IRRADLNGSNMETVIGHGLKTTDGLAVDWVARN-LYWTDTGRNTIEA 1454
Query: 13207 VNIDGSERTTVVHDR-HIPYAVDVF--ENHIYW 13296
+DGS R ++++ P A+ VF + +++W
Sbjct: 1455 SRLDGSCRKVLINNSLDEPRAIAVFPRKGYLFW 1487
>gi|27883856|ref|NP_766256.2| low density lipoprotein receptor-related
protein 4; LDLR dan [Mus musculus]
gi|17224416|gb|AAL36970.1| LDLR dan [Mus musculus]
Length = 1905
Score = 676 bits (1744), Expect = 0.0
Identities = 504/1764 (28%), Positives = 811/1764 (45%), Gaps = 42/1764 (2%)
Frame = +1
Query: 3124 CQKDPAEKIEQLCSSNSTQFQCKNGR-----CIPKEWKCDGENDCLDESDEIDEKGDKCF 3288
C A +E C+ + F C CIP +W+CDG+NDC D SDE D C
Sbjct: 15 CAHGIASSLE--CACGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDE-----DGCT 67
Query: 3289 HETECAENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNH 3468
T C+ C N K CI +D C +F C N
Sbjct: 68 LPT-CSPLDFHCDNGK-CIRRSWVCDGDNDCEDDSDE-----QDCPPRECEEDEFPCQNG 120
Query: 3469 RCIPEQWKXXXXXXXXXXXXEKLEMCGNATCAANQFSCANGRCIPIYWLCDGDNDCYDGT 3648
CI W E+ +M C+ +F C++G CI +W CDGD DC DG+
Sbjct: 121 YCIRSLWHCDGDNDCGDNSDEQCDM---RKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGS 177
Query: 3649 DEDK--ERCPPVQCSALQFRCANGRQCVPLRNHXXXXXXXXXXXXXXXXAVTAESCTPDQ 3822
DE+ P C+ +F+CA GR C+ L + + + C +
Sbjct: 178 DEESCPSAVPSPPCNLEEFQCAYGR-CI-LDIYHCDGDDDCGDWSDESDCSSHQPCRSGE 235
Query: 3823 FKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKCGNGRCILNNWLCDG 4002
F C SGLCI + W+ SDE CT+ C+++QF+C +GRC+ +W CDG
Sbjct: 236 FMC-DSGLCINSGWRCDGDADCDDQSDERN--CTTS-MCTAEQFRCRSGRCVRLSWRCDG 291
Query: 4003 ENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGG 4182
E+DC D SDE + C+ + + +C + C N + CI +LC+G C +DE
Sbjct: 292 EDDCADNSDEEN---CENT-GSPQCASDQFLCWNGR--CIGQRKLCNGINDCGDSSDESP 345
Query: 4183 ------RCARDLCSADRAGCSFKCHNSPNGPICSCPFGEQLVNKTK-CEPENECLDSSSC 4341
R + C+ + GC+ KC C+ G +L + C+ NEC + C
Sbjct: 346 QQNCRPRTGEENCNVNNGGCAQKCQMVRGAVQCTRHTGYRLTEDGRTCQDVNECAEEGYC 405
Query: 4342 SQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTF 4521
SQ C + + F C C+ GYEL D+R+CK + + +NR I +
Sbjct: 406 SQGCTNTEGAFQCWCEAGYELRPDRRSCKALG--PEPVLLFANRIDIRQVLPHRSEYTLL 463
Query: 4522 GAIVENAIALAWDSLTDRIYWSDIREKKILSANRNGTNATVFIADGLDITEGIALDWVGR 4701
+ENAIAL + + ++WSD+ +IL AN NG+N ++ GL+ G+A+DWV
Sbjct: 464 LNNLENAIALDFHHRRELVFWSDVTLDRILRANLNGSNVEEVVSTGLESPGGLAVDWVHD 523
Query: 4702 NLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQNPCIERA 4881
LYW DS + IEVANL D R +L+ Q++ +PR IA+ P +G ++WTDWG P IE +
Sbjct: 524 KLYWTDSGTSRIEVANL-DGAHRKVLLWQSLEKPRAIALHPMEGTIYWTDWGNTPRIEAS 582
Query: 4882 SMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFV 5061
SMDG+ R+II T ++WPN + +DY R+Y+ D+K I+ N DGS R V+ S+ +
Sbjct: 583 SMDGSGRRIIADTHLFWPNGLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVI--SQGL 640
Query: 5062 QHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIK 5241
HP A+ +FED +Y++D + + K+ G E + + + +HP QP K
Sbjct: 641 PHPFAITVFEDSLYWTDWHTKSINSANKF-TGKNQEIIRNKLHFPMDIHTLHPQRQPAGK 699
Query: 5242 NNPCSTN--PCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNVFGIE 5415
N C N C+HLCL + +N +TC CP G + + C FL+ ++ ++ I
Sbjct: 700 NR-CGDNNGGCTHLCLPSGQN-YTCACPTGFR-KINSHACAQSLDKFLLFARRMDIRRIS 756
Query: 5416 MNSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRS 5595
++ + ++PL+ + +A +D+ + ++ ++TD+ I R+
Sbjct: 757 FDTEDLSD-----DVIPLADVRSAVALDWDSRDDHVY----------WTDVSTDT-ISRA 800
Query: 5596 TVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVILSNDQ 5775
+G + + +++ A L DW L + T IE+ T G +I N
Sbjct: 801 KWDGTGQEVVVDTSLESPA-GLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWEN-- 857
Query: 5776 SXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAI 5955
GY++W D G A K+ RAG+D S+ VI S++L + +AI
Sbjct: 858 ----LDRPRDIVVEPMGGYMYWTDWG---ASPKIERAGMDASSRQVIISSNLTWPNGLAI 910
Query: 5956 DTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAFDSIEV 6135
D + R+Y+++A I DG R ++ P GL YG R+++ D SI+
Sbjct: 911 DYGSQRLYWADAGMKTIEFAGLDGSKRKVLIGSQLPHPFGLTLYGQRIYWTDWQTKSIQS 970
Query: 6136 A-TINGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHINNGNCDHICI----PLMF 6300
A + G + ++++ENL +I + C + NG C H+C+ P F
Sbjct: 971 ADRLTGLDRET----LQENLENLMDIHVFHRQRPPVTTLCAVENGGCSHLCLRSPNPSGF 1026
Query: 6301 AQRTCTCANG--YVKDGQTSCKLFDESFVIVATKTKV------------IGYPIDETQSK 6438
+CTC G ++DG+T C SF+I A + V + PI+ T
Sbjct: 1027 ---SCTCPTGINLLRDGKT-CSPGMNSFLIFARRIDVRMVSLDIPYFADVVVPINMTMKN 1082
Query: 6439 GVAMEPIGGLSITGVDYDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIK 6618
+A IG + G Y +S ++ AS + S +I + G T
Sbjct: 1083 TIA---IGVDPLEGKVYWSDSTLHRISRAS----------LDGSQHEDII--TTGLQTTD 1127
Query: 6619 SLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWAD 6798
LA+D I +Y+ D IEV LDG+ RK+L+ ++P +I + ++YW D
Sbjct: 1128 GLAVDAIGRKVYWT--DTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTD 1185
Query: 6799 QGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTP 6978
G+ ++RS +DGS R V++++ + P L VD S + W+DA + I G
Sbjct: 1186 WGENAKLERSGMDGSDRTVLINNNLGWPNGLTVDKTSSQLLWADAHTERIEVADLNGANR 1245
Query: 6979 ELVRSDIASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVA 7158
+ S + G+ L +YWTD + + RA +L V ++L + D+
Sbjct: 1246 HTLVSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKSTGSNVIL-----VRSNLPGLMDIQ 1300
Query: 7159 VFSSNNQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCARGV-LKG--RTCE-EPD 7326
QP + C R C+ LC P + +C+C G+ LKG +TC+ P+
Sbjct: 1301 AV-DRAQPLGFNKC----GSRNGGCSHLCLPRPSSF--SCACPTGIQLKGDRKTCDPSPE 1353
Query: 7327 TYIMFSDGDKIIDVAIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVNI 7506
TY++FS I ++++ D + P P ++N+ + D D +VY+ + V +++
Sbjct: 1354 TYLLFSSRGSIRRISLDTDDHTD--VHVPVPGLNNVISLDYDSVHGKVYY---TDVFLDV 1408
Query: 7507 SWFSMNNAENPRLVFGASKQPHAKEIRHISDMKLDWLTQKIYFT-TGRGG-KVMAIDTAG 7680
+ N N V G ++ + +DW+ + +Y+T TGR + +D +
Sbjct: 1409 IRRADLNGSNMETVIGHG-------LKTTDGLAVDWVARNLYWTDTGRNTIEASRLDGSC 1461
Query: 7681 EHLSTIASGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESI 7860
+ S D A+A+ P G LFW+D G+ +IER+NL G RKV+++ +
Sbjct: 1462 RKVLINNSLDEPRAIAVFPRKGYLFWTDWGHIA-------KIERANLDGSERKVLINTDL 1514
Query: 7861 SLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGY-RAKSLDIWDRWLYMSDP 8037
P + +D+ ++IYW D + IE AD +G+ R+V+ S +L DRW+Y +D
Sbjct: 1515 GWPNGLTLDYDTRRIYWVDAHLDRIESADLNGKLRQVLVSHVSHPFALTQQDRWIYWTDW 1574
Query: 8038 LSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGGC 8217
+ + R+DK SG E V+++ + G + + +T C +NGGC
Sbjct: 1575 QTKSIQRVDKYSGRNKETVLAN--VEGLMDIIVVSPQRQTGTNACG--------VNNGGC 1624
Query: 8218 DQLCTVVADDIGLAASKVQCSCND 8289
LC A D C+C D
Sbjct: 1625 THLCFARASDF-------VCACPD 1641
Score = 459 bits (1181), Expect = e-127
Identities = 319/1040 (30%), Positives = 482/1040 (45%), Gaps = 55/1040 (5%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDT-----YTWH-- 315
C+ DF C++GKCIR W P C+ D++ C WH
Sbjct: 71 CSPLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPCQNGYCIRSLWHCD 130
Query: 316 --------------------------SVSCIAEYQRCDNITDCADGSDEKDCPASTVD-- 411
SCIAE+ CD TDC DGSDE+ CP++
Sbjct: 131 GDNDCGDNSDEQCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEESCPSAVPSPP 190
Query: 412 CSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQ 591
C+ + F CA GR D+ CDG DC D SDE D CS +H C +F C D CI
Sbjct: 191 CNLEE-FQCAYGRCILDIYH-CDGDDDCGDWSDESD-CS-SHQPCRSGEFMC-DSGLCIN 245
Query: 592 KSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDEC 771
W CDG DC D SDE + C CTA +F+C++ RC +RCD DDC DNSDE+ C
Sbjct: 246 SGWRCDGDADCDDQSDERN-CTTSMCTAEQFRCRSGRCVRLSWRCDGEDDCADNSDEENC 304
Query: 772 ---GEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLG-------- 918
G +C ++ C G CI Q KLC+G DC D +DE QN P G
Sbjct: 305 ENTGSPQCASDQFLC-WNGRCIGQRKLCNGINDCGDSSDESP-QQNCRPRTGEENCNVNN 362
Query: 919 --CQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCL 1092
C C +CT +GY+L + RTC D+NECAE GYC Q C N F C C
Sbjct: 363 GGCAQKCQMVRGAVQCTRHTGYRLTED-GRTCQDVNECAEEGYCSQGCTNTEGAFQCWCE 421
Query: 1093 GDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKLASGE 1272
G + R C + + + LF A R + ++ P E L + E
Sbjct: 422 A-----------GYELRPDRRSCKALGPEPVLLF-ANRIDIRQVLPHR-SEYTLLLNNLE 468
Query: 1273 FIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNT 1452
+DF + +FW+D A+++ S ++++ L P LAVDW+ +
Sbjct: 469 NAIALDFHHRRELVFWSDVTLDRILRANLNG----SNVEEVVSTGLESPGGLAVDWVHDK 524
Query: 1453 LYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFT---NQLKLEAAAM 1623
LY +SG+ RI+V++ DG R VLL L P IAL P+ G +++T N ++EA++M
Sbjct: 525 LYWTDSGTSRIEVANLDGAHRKVLLWQSLEKPRAIALHPMEGTIYWTDWGNTPRIEASSM 584
Query: 1624 DGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRR-IVAQGMNVVP 1800
DG+ RR + +TH +G+ +D +R+YWVD K +E + G+ R+ +++QG+ P
Sbjct: 585 DGSGRRIIADTHLFWPNGLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVISQGL---P 641
Query: 1801 HPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPG 1980
HPF + +F+ LYWTDW + KF + + N + FPM I HP QP G
Sbjct: 642 HPFAITVFEDSLYWTDWHTKSINSANKFTGKNQEIIRNKLH--FPMDIHTLHPQRQPA-G 698
Query: 1981 QSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGKRCIDSID-YLL 2157
++ C N C +C+ S G Y CACP G + +N C S+D +LL
Sbjct: 699 KNRC-------GDNNGGCTHLCLPS------GQNYTCACPTGFRKINSHACAQSLDKFLL 745
Query: 2158 FSSNKIVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIY 2337
F+ +R I + + L++ V+P++ + ++ D + ++ D+ +TI
Sbjct: 746 FARRMDIRRI--SFDTEDLSDDVIPLADVRSA-----VALDWDSRDDHVYWTDVSTDTIS 798
Query: 2338 RIRPDGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVR 2517
R + DG G V+ T + ++ DW++ +LY+ D + +EV + D +R
Sbjct: 799 RAKWDGTGQEVVVDTSLESPAGLAIDWVTNKLYWTDAGTDRIEV--------ANTDGSMR 850
Query: 2518 RQLITELRD-PVSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAI 2694
LI E D P +VV P G +++ + I R +D + QVI ++ L P+ +AI
Sbjct: 851 TVLIWENLDRPRDIVVEPMGGYMYWTDWGASPKIERAGMDASSRQVIISSNLTWPNGLAI 910
Query: 2695 DFAENRLCWGDTLLKTISCMDFDG-KNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRR 2871
D+ RL W D +KTI DG K V + P P +T+ + IY+ + SI+
Sbjct: 911 DYGSQRLYWADAGMKTIEFAGLDGSKRKVLIGSQLPHPFGLTLYGQRIYWTDWQTKSIQS 970
Query: 2872 VHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQCTQLCFATPSES 3051
+ G + ++E + ++ + Q P+ + C+ LC +P+ S
Sbjct: 971 ADRLTGLDRETLQE---NLENLMDIHVFHRQRPPV---TTLCAVENGGCSHLCLRSPNPS 1024
Query: 3052 HPNELEAKCACRQGFMINKE 3111
C C G + ++
Sbjct: 1025 -----GFSCTCPTGINLLRD 1039
Score = 453 bits (1166), Expect = e-125
Identities = 272/769 (35%), Positives = 386/769 (49%), Gaps = 13/769 (1%)
Frame = +1
Query: 8575 CGDG-SDELDCPSAVACAEGTFPCSNGH-----CINQTKVCDGHNDCHDEQVSDESLATC 8736
C G + L+C AC F C+ CI CDG NDC D SDE T
Sbjct: 15 CAHGIASSLEC----ACGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDH--SDEDGCTL 68
Query: 8737 PGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGR 8916
P C + C N CI+ + +CDG +DC D +DE C ++C + C +G
Sbjct: 69 P----TCSPLDFHCDNGK-CIRRSWVCDGDNDCEDDSDEQD--CPPRECEEDEFPCQNGY 121
Query: 8917 CIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXX 9096
CI W CDGDNDC D DE + C D F+C + CI+ +
Sbjct: 122 CIRSLWHCDGDNDCGDNSDEQ-------CDMRKC-SDKEFRCSDGSCIAEHWYCDGDTDC 173
Query: 9097 XXXXXXHS-RHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTE 9273
S + C +EF C CI + CDGD C DES
Sbjct: 174 KDGSDEESCPSAVPSPPCNLEEFQCAYG--------RCILDIYHCDGDDDCGDWSDESD- 224
Query: 9274 LCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCANHK 9453
C + + C GEF C + CI+S W CDGD DC D SDE NCT S C + F+C + +
Sbjct: 225 -CSSHQP-CRSGEFMCDSGLCINSGWRCDGDADCDDQSDER-NCTTSMCTAEQFRCRSGR 281
Query: 9454 CVPNSWKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFD 9633
CV SW+CDG DDC D SDE++C +N+ S Q C++ QF C +G CI K+C+ D
Sbjct: 282 CVRLSWRCDGEDDCADNSDEENC-ENTGSPQ----CASDQFLCWNGRCIGQRKLCNGIND 336
Query: 9634 CTDRSDESSLCFI------DECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCH 9795
C D SDES + C++ C QKC ++ +C G+ + D ++C
Sbjct: 337 CGDSSDESPQQNCRPRTGEENCNVNNGG-CAQKCQMVRGAVQCTRHTGYRLT-EDGRTCQ 394
Query: 9796 NVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIR 9975
+VNEC E CSQ C + G+++C C GY+L D SCK + PEP L AN+ IR
Sbjct: 395 DVNECAEE-GYCSQGCTNTEGAFQCWCEAGYELRPDRRSCKA--LGPEPVLLFANRIDIR 451
Query: 9976 KISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVL 10155
++ ++Y L +N ++LD + + D R+LR +L+ S+ E V+
Sbjct: 452 QVLPHRSEYTLLLNNLENAIALDFHHRRELVFWSDVTLDRILRANLNG-----SNVEEVV 506
Query: 10156 RHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKG 10335
+ G+AVDWV KLY + I V LDG K L+ +++P+AI +HP +G
Sbjct: 507 STGLESPGGLAVDWVHDKLYWTDSGTSRIEVANLDGAHRKVLLWQSLEKPRAIALHPMEG 566
Query: 10336 YLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNE 10515
+++T+W P I ++DGS +A+ L WPN + IDY R++W DA +
Sbjct: 567 TIYWTDWGNTPRIEASSMDGSGRRI-----IADTHLFWPNGLTIDYAGRRMYWVDAKHHV 621
Query: 10516 IGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTV 10695
I + DG+ R+ + +Q H ++ VF+D LYW DW+ + + +K+TGKN+ I++ +
Sbjct: 622 IERANLDGSHRKAVISQGLPHPFAITVFEDSLYWTDWHTKSINSANKFTGKNQEIIRNKL 681
Query: 10696 QLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQF 10842
P D+ +HP RQPA N CGDNNGGC+HLCL G YTC+CP F
Sbjct: 682 HFPMDIHTLHPQRQPAGKNRCGDNNGGCTHLCL--PSGQNYTCACPTGF 728
Score = 325 bits (832), Expect = 3e-86
Identities = 237/776 (30%), Positives = 340/776 (43%), Gaps = 47/776 (6%)
Frame = +1
Query: 11359 ECAQIECKKGWTRCSSSY----RCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCA 11526
ECA C + C+ S CIP C+G +DC D+SDED PTC + +F C
Sbjct: 24 ECA---CGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDEDGCTLPTCSPL-DFHC- 78
Query: 11527 TSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQ 11706
+GKCI R W+CD +NDC D+SDE D R C E EF C +G CI CDG
Sbjct: 79 DNGKCIRRSWVCDGDNDCEDDSDEQDCP----PRECEEDEFPCQNGYCIRSLWHCDGDND 134
Query: 11707 CSDGLDESQCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCED-VSRRTCSP 11883
C D DE QC +R+C +C DG+CIAEH +CD DC + +DE C V C+
Sbjct: 135 CGDNSDE-QCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEESCPSAVPSPPCNL 193
Query: 11884 FEFECANSVCIPRKFMXXXXXXXXXXSDETSSE----CRSAQ--CDPPL----------- 12012
EF+CA CI + SDE+ CRS + CD L
Sbjct: 194 EEFQCAYGRCILDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMCDSGLCINSGWRCDGD 253
Query: 12013 --------------------RFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSFS 12132
+FRC R C+ + C+G +DC N SDE C +
Sbjct: 254 ADCDDQSDERNCTTSMCTAEQFRCRSGR-CVRLSWRCDGEDDCADN--SDEE--NCENTG 308
Query: 12133 EYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEI---GCSKHGGKTSCEAFGNNGGC 12303
C+SDQF C NG+C+ C+ +DCGD+SDE C G+ +C NNGGC
Sbjct: 309 S-PQCASDQFLCWNGRCIGQRKLCNGINDCGDSSDESPQQNCRPRTGEENCNV--NNGGC 365
Query: 12304 KHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNTKGSYLCRCHEDY 12483
C VR C G+R + + C D++ECA C+Q C NT+G++ C C Y
Sbjct: 366 AQKCQMVRGAVQCTRHTGYRLT-EDGRTCQDVNECAEEGYCSQGCTNTEGAFQCWCEAGY 424
Query: 12484 ENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXX 12663
E + C+A G ++ + Q+ H R
Sbjct: 425 ELR-----PDRRSCKALGPEPVLLFANRIDIRQVLPH-----RSEYTLLLNNLENAIALD 474
Query: 12664 XXPRKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFI 12843
R+EL++W S+ T+ R AN N S+ + + + P +AVD+ L+
Sbjct: 475 FHHRRELVFW---SDVTLDRILRANLNGSNVEEVVSTGLES----PGGLAVDWVHDKLYW 527
Query: 12844 AAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPS 13023
+ T I V DG + K ++ L++P A+ P
Sbjct: 528 T-----------------------DSGTSRIEVANLDGAHRKVLLWQSLEKPRAIALHPM 564
Query: 13024 AGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVD 13203
G I ++D G +IE + MDG+ R+II +F P + ID G R+YWVD K+ ++
Sbjct: 565 EGTIYWTDWGNTPRIEASSMDGSGRRIIADTHLFWPNGLTIDYA-GRRMYWVDAKHHVIE 623
Query: 13204 AVNIDGSERTTVV-HDRHIPYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLED 13380
N+DGS R V+ P+A+ VFE+ +YW +K++ +KF ++ + L
Sbjct: 624 RANLDGSHRKAVISQGLPHPFAITVFEDSLYWTDWHTKSINSANKFTGKNQEIIRNKLHF 683
Query: 13381 GHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPS-TGFACLCPDGIVPQLDGSCA 13545
+ + + G C+HLC LPS + C CP G +CA
Sbjct: 684 PMDIHTLHPQRQPAGKNRCGDNNGGCTHLC--LPSGQNYTCACPTGFRKINSHACA 737
Score = 243 bits (619), Expect = 1e-61
Identities = 197/730 (26%), Positives = 335/730 (44%), Gaps = 10/730 (1%)
Frame = +1
Query: 1018 NECAEF-GYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLF 1194
N C + G C LC +TC+C G K N + + + DK LF
Sbjct: 700 NRCGDNNGGCTHLCLPSGQNYTCAC---------PTGFRKIN----SHACAQSLDKFLLF 746
Query: 1195 VARREGLYRLNPKNPD--EEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDE 1368
ARR + R++ D ++V LA +D+D D ++WTD + A D
Sbjct: 747 -ARRMDIRRISFDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDGT 805
Query: 1369 GEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLP 1548
G+ + SL+S P LA+DW+TN LY ++G+ RI+V++ DG RTVL+ + L P
Sbjct: 806 GQ-EVVVDTSLES---PAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRP 861
Query: 1549 LDIALDPLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVD 1719
DI ++P+ G M++T+ K+E A MD ++R+ +++++ +G+ +D ++R+YW D
Sbjct: 862 RDIVVEPMGGYMYWTDWGASPKIERAGMDASSRQVIISSNLTWPNGLAIDYGSQRLYWAD 921
Query: 1720 PKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKF-GSDT 1896
+ +E G+ R+++ +PHPFGL L+ Q +YWTDW + ++ G D
Sbjct: 922 AGMKTIEFAGLDGSKRKVLIGSQ--LPHPFGLTLYGQRIYWTDWQTKSIQSADRLTGLDR 979
Query: 1897 KLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFG 2076
+ L N EN M I +H Q P + C N C +C+ S + GF
Sbjct: 980 ETLQENLEN---LMDIHVFH--RQRPPVTTLCAV-------ENGGCSHLCLRSPNPSGF- 1026
Query: 2077 VGYKCACPIGQKLV-NGKRCIDSID-YLLFSSNKIVRGIFPEINEKALAEAVLPISPISQ 2250
C CP G L+ +GK C ++ +L+F+ VR + +I A+ V+PI+ +
Sbjct: 1027 ---SCTCPTGINLLRDGKTCSPGMNSFLIFARRIDVRMVSLDI--PYFADVVVPINMTMK 1081
Query: 2251 RRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWISKQ 2430
I + D +++D + I R DG ++ T ++ D I ++
Sbjct: 1082 NTIA----IGVDPLEGKVYWSDSTLHRISRASLDGSQHEDIITTGLQTTDGLAVDAIGRK 1137
Query: 2431 LYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITE-LRDPVSVVVHPWKGLLFYAEAMRP 2607
+Y+ D N +EV + D +R+ L+ + L P ++V++ G +++ +
Sbjct: 1138 VYWTDTGTNRIEVGNL--------DGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTDWGEN 1189
Query: 2608 AAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVKLD 2787
A + R +DG + V+ N LG P+ + +D ++L W D + I D +G N L
Sbjct: 1190 AKLERSGMDGSDRTVLINNNLGWPNGLTVDKTSSQLLWADAHTERIEVADLNGANRHTLV 1249
Query: 2788 IDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQN 2967
P +T+++ YIY+ + SI R K G +VR ++ L +
Sbjct: 1250 SPVQHPYGLTLLDSYIYWTDWQTRSIHRADKSTGSNVILVRS------NLPGLMDIQAVD 1303
Query: 2968 QPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINKENNHSCQKDPAEK 3147
+ P + R C+ LC PS CAC G + K + +C DP+ +
Sbjct: 1304 RAQPLGFNKCGSRNGGCSHLCLPRPS-------SFSCACPTGIQL-KGDRKTC--DPSPE 1353
Query: 3148 IEQLCSSNST 3177
L SS +
Sbjct: 1354 TYLLFSSRGS 1363
Score = 232 bits (591), Expect = 2e-58
Identities = 128/349 (36%), Positives = 186/349 (52%), Gaps = 3/349 (0%)
Frame = +1
Query: 9802 NECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKI 9981
N+C GCS C + S+ C C G QL D +C + PE + L +++ IR+I
Sbjct: 1311 NKCGSRNGGCSHLCLPRPSSFSCACPTGIQLKGDRKTC---DPSPETYLLFSSRGSIRRI 1367
Query: 9982 SIDGNKY---ELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETV 10152
S+D + + + G +NV+SLD D K Y D + R DL+ S+ ETV
Sbjct: 1368 SLDTDDHTDVHVPVPGLNNVISLDYDSVHGKVYYTDVFLDVIRRADLNG-----SNMETV 1422
Query: 10153 LRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGK 10332
+ H + T+G+AVDWV R LY + +I LDG K LI + + +P+AI V P K
Sbjct: 1423 IGHGLKTTDGLAVDWVARNLYWTDTGRNTIEASRLDGSCRKVLINNSLDEPRAIAVFPRK 1482
Query: 10333 GYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLN 10512
GYLF+T+W I R LDGS L DLGWPN + +DY + R++W DAHL+
Sbjct: 1483 GYLFWTDWGHIAKIERANLDGSERK-----VLINTDLGWPNGLTLDYDTRRIYWVDAHLD 1537
Query: 10513 EIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKT 10692
I D +G R + SH ++ D ++YW DW + + R DK++G+N+ +
Sbjct: 1538 RIESADLNGK-LRQVLVSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVLAN 1596
Query: 10693 VQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQ 10839
V+ D+ +V P RQ N CG NNGGC+HLC A + + C+CPD+
Sbjct: 1597 VEGLMDIIVVSPQRQTG-TNACGVNNGGCTHLCF--ARASDFVCACPDE 1642
Score = 223 bits (567), Expect = 1e-55
Identities = 205/737 (27%), Positives = 325/737 (43%), Gaps = 22/737 (2%)
Frame = +1
Query: 994 FHRTCSDINE-CA-EFGYCDQLCAN--HRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYC 1161
FHR + CA E G C LC + GF+C+C P NL G
Sbjct: 995 FHRQRPPVTTLCAVENGGCSHLCLRSPNPSGFSCTC------------PTGINLLRDGKT 1042
Query: 1162 VSNNADKMKLFVARREGLYRLN---PKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRL 1332
S + +F ARR + ++ P D V + + I D + K++W+D
Sbjct: 1043 CSPGMNSFLIF-ARRIDVRMVSLDIPYFADVVVPINMTMKNTIAIGVDPLEGKVYWSDST 1101
Query: 1333 AHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGER 1512
H A +D SQ + + L LAVD I +Y ++G+ RI+V + DG
Sbjct: 1102 LHRISRASLDG----SQHEDIITTGLQTTDGLAVDAIGRKVYWTDTGTNRIEVGNLDGSM 1157
Query: 1513 RTVLLADGLTLPLDIALDPLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHTHQVSGIV 1683
R VL+ L P I L G M++T+ KLE + MDG++R L+N + +G+
Sbjct: 1158 RKVLVWQNLDSPRAIVLYHEMGFMYWTDWGENAKLERSGMDGSDRTVLINNNLGWPNGLT 1217
Query: 1684 VDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLG 1863
VD T+ ++ W D +R+E D G +R + ++ V HP+GL L D Y+YWTDW
Sbjct: 1218 VDKTSSQLLWADAHTERIEVADLNGANRHTL---VSPVQHPYGLTLLDSYIYWTDWQTRS 1274
Query: 1864 VIQVEKF-GSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEG 2040
+ + +K GS+ L+ SN + + P+ G ++C + N C
Sbjct: 1275 IHRADKSTGSNVILVRSNLPGLMDIQAVDRAQPL-----GFNKCGSR-------NGGCSH 1322
Query: 2041 MCILSKDNGGFGVGYKCACPIGQKLVNGKRCIDSID--YLLFSSNKIVRGIFPEINEKAL 2214
+C+ + + CACP G +L ++ D YLLFSS +R I + ++
Sbjct: 1323 LCLPRPSS------FSCACPTGIQLKGDRKTCDPSPETYLLFSSRGSIRRISLDTDDHTD 1376
Query: 2215 AEAVLPISPISQRRIGMYFEVECD---VHGNSFFYADIMDNTIYRIRPDGEGAAPVL--- 2376
+P G+ + D VHG +Y D+ + I R +G V+
Sbjct: 1377 VHVPVP---------GLNNVISLDYDSVHGK-VYYTDVFLDVIRRADLNGSNMETVIGHG 1426
Query: 2377 VTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITE-LRDPVS 2553
+ DGL + DW+++ LY+ D RN++E ++ D R+ LI L +P +
Sbjct: 1427 LKTTDGL---AVDWVARNLYWTDTGRNTIEASRL--------DGSCRKVLINNSLDEPRA 1475
Query: 2554 VVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTL 2733
+ V P KG LF+ + A I R ++DG +V+ NT LG P+ + +D+ R+ W D
Sbjct: 1476 IAVFPRKGYLFWTDWGHIAKIERANLDGSERKVLINTDLGWPNGLTLDYDTRRIYWVDAH 1535
Query: 2734 LKTISCMDFDGKNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVRE 2913
L I D +GK L P A+T + +IY+ + SI+RV K +G + V
Sbjct: 1536 LDRIESADLNGKLRQVLVSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVL- 1594
Query: 2914 FGADERSIFSLKACSHQNQPIPDDSREHPCRASQ--CTQLCFATPSESHPNELEAKCACR 3087
A+ + + S Q Q + + C + CT LCFA S + CAC
Sbjct: 1595 --ANVEGLMDIIVVSPQRQ-----TGTNACGVNNGGCTHLCFARAS-------DFVCACP 1640
Query: 3088 QGFMINKENNHSCQKDP 3138
++ + H C P
Sbjct: 1641 -----DEPDGHPCSLVP 1652
Score = 194 bits (492), Expect = 7e-47
Identities = 110/361 (30%), Positives = 170/361 (46%), Gaps = 3/361 (0%)
Frame = +1
Query: 9802 NECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKI 9981
N C + GC+ C +Y C C G++ + H+C ++ + F L A + IR+I
Sbjct: 700 NRCGDNNGGCTHLCLPSGQNYTCACPTGFR-KINSHACAQSL---DKFLLFARRMDIRRI 755
Query: 9982 SIDGNKYE---LAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETV 10152
S D + + V+LD D + Y D + R D + E V
Sbjct: 756 SFDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDG-----TGQEVV 810
Query: 10153 LRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGK 10332
+ ++ G+A+DWV KLY + I V DG LI + + +P+ IVV P
Sbjct: 811 VDTSLESPAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRPRDIVVEPMG 870
Query: 10333 GYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLN 10512
GY+++T+W P I R +D S + +L WPN +AIDY S RL+W DA +
Sbjct: 871 GYMYWTDWGASPKIERAGMDASSRQV-----IISSNLTWPNGLAIDYGSQRLYWADAGMK 925
Query: 10513 EIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKT 10692
I F DG+ R+ + + H + ++ +YW DW + + D+ TG + L++
Sbjct: 926 TIEFAGLDGSKRKVLIGSQLPHPFGLTLYGQRIYWTDWQTKSIQSADRLTGLDRETLQEN 985
Query: 10693 VQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTCE 10872
++ D+ + H R P C NGGCSHLCL +G++C+CP LL D KTC
Sbjct: 986 LENLMDIHVFHRQRPPV-TTLCAVENGGCSHLCLRSPNPSGFSCTCPTGINLLRDGKTCS 1044
Query: 10873 P 10875
P
Sbjct: 1045 P 1045
Score = 191 bits (484), Expect = 6e-46
Identities = 111/357 (31%), Positives = 169/357 (47%), Gaps = 6/357 (1%)
Frame = +1
Query: 9826 GCSQKC--DDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNK 9999
GCS C + C C G L D +C F + A + +R +S+D
Sbjct: 1012 GCSHLCLRSPNPSGFSCTCPTGINLLRDGKTCSPGM---NSFLIFARRIDVRMVSLDIPY 1068
Query: 10000 YELAAQGFD----NVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNV 10167
+ + N +++ +D E K Y D R+ R LD S +E ++ +
Sbjct: 1069 FADVVVPINMTMKNTIAIGVDPLEGKVYWSDSTLHRISRASLDG-----SQHEDIITTGL 1123
Query: 10168 YGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFF 10347
T+G+AVD +GRK+Y + I V LDG K L+ + P+AIV++ G++++
Sbjct: 1124 QTTDGLAVDAIGRKVYWTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYW 1183
Query: 10348 TEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFM 10527
T+W + R +DGS L ++LGWPN + +D S +L W DAH I
Sbjct: 1184 TDWGENAKLERSGMDGSDRT-----VLINNNLGWPNGLTVDKTSSQLLWADAHTERIEVA 1238
Query: 10528 DFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPN 10707
D +G RH H + + D Y+YW DW R + R DK TG N +++ +
Sbjct: 1239 DLNG-ANRHTLVSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKSTGSNVILVRSNLPGLM 1297
Query: 10708 DLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTCEPN 10878
D++ V QP N CG NGGCSHLCL + ++C+CP L D+KTC+P+
Sbjct: 1298 DIQAV-DRAQPLGFNKCGSRNGGCSHLCL--PRPSSFSCACPTGIQLKGDRKTCDPS 1351
Score = 159 bits (403), Expect = 1e-36
Identities = 117/387 (30%), Positives = 160/387 (41%), Gaps = 22/387 (5%)
Frame = +1
Query: 8383 PYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCN 8562
P +F C +G CI CD DC D SDE C R C ED C N CI S C+
Sbjct: 73 PLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQD--CPPRECEEDEFPCQNGYCIRSLWHCD 130
Query: 8563 HIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPG 8742
+DCGD SDE C C++ F CS+G CI + CDG DC D + + P
Sbjct: 131 GDNDCGDNSDE-QCDMR-KCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEESCPSAVPS 188
Query: 8743 LPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCI 8922
P C + +C CI CDG DDCGD +DE+ +Q C C SG CI
Sbjct: 189 PP--CNLEEFQCAYGR-CILDIYHCDGDDDCGDWSDESDC-SSHQPCRSGEFMCDSGLCI 244
Query: 8923 PETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXX 9102
W+CDGD DC D DE NCT + +C + F+C + +C+ ++
Sbjct: 245 NSGWRCDGDADCDDQSDE--RNCTTS----MCTAEQ-FRCRSGRCVRLSWRCDGEDDCAD 297
Query: 9103 XXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTEL-C 9279
+ G+ C +F C + CI + LC+G C DES + C
Sbjct: 298 NSDEENCENTGSPQCASDQFLCWNG--------RCIGQRKLCNGINDCGDSSDESPQQNC 349
Query: 9280 --KTEKKECNKGEFRCSNQ--------HCIHSTW--------ECDGDNDCLDGSDEHANC 9405
+T ++ CN C+ + C T C N+C + C
Sbjct: 350 RPRTGEENCNVNNGGCAQKCQMVRGAVQCTRHTGYRLTEDGRTCQDVNECAEEGYCSQGC 409
Query: 9406 TYSSCQPDFFQC---ANHKCVPNSWKC 9477
T + FQC A ++ P+ C
Sbjct: 410 TNTE---GAFQCWCEAGYELRPDRRSC 433
Score = 150 bits (379), Expect = 9e-34
Identities = 104/329 (31%), Positives = 142/329 (42%), Gaps = 9/329 (2%)
Frame = +1
Query: 8362 PAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCI 8541
P +EC F C +G CI CD DC D SDE C+ R C + C++ CI
Sbjct: 106 PPRECEED-EFPCQNGYCIRSLWHCDGDNDCGDNSDEQ---CDMRKCSDKEFRCSDGSCI 161
Query: 8542 DSAKKCNHIDDCGDGSDELDCPSAV---ACAEGTFPCSNGHCINQTKVCDGHNDCHDEQV 8712
C+ DC DGSDE CPSAV C F C+ G CI CDG +DC D
Sbjct: 162 AEHWYCDGDTDCKDGSDEESCPSAVPSPPCNLEEFQCAYGRCILDIYHCDGDDDCGD--W 219
Query: 8713 SDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQH 8892
SDES + CR + C ++ +CI CDG DC D++DE C C
Sbjct: 220 SDESDCSSHQ---PCRSGEFMC-DSGLCINSGWRCDGDADCDDQSDERN--CTTSMCTAE 273
Query: 8893 YVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAF 9072
RC SGRC+ +W+CDG++DC+D DE NC +T G C D F C N +CI +
Sbjct: 274 QFRCRSGRCVRLSWRCDGEDDCADNSDE--ENCENT-GSPQCASDQ-FLCWNGRCIGQRK 329
Query: 9073 IXXXXXXXXXXXXXHSRHGC----GNRTCTDQEFHCTSNAKLAQPKYECIPRAW--LCDG 9234
+ + C G C C ++ + +C L +
Sbjct: 330 LCNGINDCGDSSDESPQQNCRPRTGEENCNVNNGGCAQKCQMVRGAVQCTRHTGYRLTED 389
Query: 9235 DVTCAGGEDESTELCKTEKKECNKGEFRC 9321
TC + + E ++ +G F+C
Sbjct: 390 GRTCQDVNECAEEGYCSQGCTNTEGAFQC 418
Score = 131 bits (330), Expect = 4e-28
Identities = 99/313 (31%), Positives = 128/313 (40%), Gaps = 7/313 (2%)
Frame = +1
Query: 11590 SDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQ 11769
+ L+ +CG + C+ S + CIP CDG C D DE CTL C P
Sbjct: 20 ASSLECACGRSHFTCAVSAL--GECTCIPAQWQCDGDNDCGDHSDEDGCTLPTCSPLDFH 77
Query: 11770 CDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFECANSVCIPRKFMXXXXXX 11949
CD+G CI CD DC + +DE C R C EF C N CI +
Sbjct: 78 CDNGKCIRRSWVCDGDNDCEDDSDEQDCPP---RECEEDEFPCQNGYCIRSLWHCDGDND 134
Query: 11950 XXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDFSDEHLSMCSSF 12129
SDE +C +C FRC+ C+ C+G DC D SDE C S
Sbjct: 135 CGDNSDE---QCDMRKCSDK-EFRCSDGS-CIAEHWYCDGDTDC--KDGSDEE--SCPSA 185
Query: 12130 SEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKH 12309
C+ ++F+CA G+C+ CD DDCGD SDE CS H S E ++G C
Sbjct: 186 VPSPPCNLEEFQCAYGRCILDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMCDSGLC-- 243
Query: 12310 ICTDVRDGFYCHCRDGFRP-DPQSPKECIDIDECAG------NNTCTQLCLNTKGSYLCR 12468
+ G+ C DG D QS + C + C +L G C
Sbjct: 244 ----INSGWRC---DGDADCDDQSDERNCTTSMCTAEQFRCRSGRCVRLSWRCDGEDDCA 296
Query: 12469 CHEDYENNVVVGS 12507
+ D EN GS
Sbjct: 297 DNSDEENCENTGS 309
Score = 106 bits (265), Expect = 1e-20
Identities = 77/290 (26%), Positives = 130/290 (44%), Gaps = 2/290 (0%)
Frame = +1
Query: 12673 RKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAV 12852
R + +YW D S TI R+ GQ++ VD + P +A+D+ T L+
Sbjct: 783 RDDHVYWTDVSTDTISRA-----KWDGTGQEVVVDTSLES--PAGLAIDWVTNKLYWT-- 833
Query: 12853 SENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGR 13032
+ T I V DG ++ +L +P ++ P G
Sbjct: 834 ---------------------DAGTDRIEVANTDGSMRTVLIWENLDRPRDIVVEPMGGY 872
Query: 13033 ICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVN 13212
+ ++D G KIE A MD + RQ+I+ + P +AID G R+YW D + ++
Sbjct: 873 MYWTDWGASPKIERAGMDASSRQVIISSNLTWPNGLAIDYG-SQRLYWADAGMKTIEFAG 931
Query: 13213 IDGSERTTVVHDR-HIPYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHT 13389
+DGS+R ++ + P+ + ++ IYW ++K++ D+ L +LE+
Sbjct: 932 LDGSKRKVLIGSQLPHPFGLTLYGQRIYWTDWQTKSIQSADRLTGLDRETLQENLENLMD 991
Query: 13390 VRVSQKYAKDTQRTVSGCERAQCSHLCVSLPS-TGFACLCPDGIVPQLDG 13536
+ V + + T+ E CSHLC+ P+ +GF+C CP GI DG
Sbjct: 992 IHVFHR-QRPPVTTLCAVENGGCSHLCLRSPNPSGFSCTCPTGINLLRDG 1040
Score = 102 bits (255), Expect = 2e-19
Identities = 56/157 (35%), Positives = 72/157 (45%), Gaps = 5/157 (3%)
Frame = +1
Query: 520 SCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNK 699
+C R+H C + CI W CDG DC D SDE D C C+ +F C N
Sbjct: 26 ACGRSHFTC---AVSALGECTCIPAQWQCDGDNDCGDHSDE-DGCTLPTCSPLDFHCDNG 81
Query: 700 RCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGAD 879
+C R + CD +DC D+SDE +C C ++ C G+CI L CDG DC D +D
Sbjct: 82 KCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPCQ-NGYCIRSLWHCDGDNDCGDNSD 140
Query: 880 EQQCSQNLC--PSLGCQAGCHPSPH---GGECTCPSG 975
E QC C C G + H G+ C G
Sbjct: 141 E-QCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDG 176
Score = 95.9 bits (237), Expect = 3e-17
Identities = 55/199 (27%), Positives = 105/199 (52%)
Frame = +1
Query: 12952 DGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSP 13131
DG K +V +L P A++ G + ++D G +AK+E + MDG+ R +++ + + P
Sbjct: 1154 DGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTDWGENAKLERSGMDGSDRTVLINNNLGWP 1213
Query: 13132 TSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSRES 13311
+ +D+ +++ W D R++ +++G+ R T+V PY + + +++IYW ++
Sbjct: 1214 NGLTVDK-TSSQLLWADAHTERIEVADLNGANRHTLVSPVQHPYGLTLLDSYIYWTDWQT 1272
Query: 13312 KTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTG 13491
++++ DK V ++ S+L ++ + A+ G CSHLC+ PS+
Sbjct: 1273 RSIHRADKSTGSNVILVRSNLPGLMDIQAVDR-AQPLGFNKCGSRNGGCSHLCLPRPSS- 1330
Query: 13492 FACLCPDGIVPQLDGSCAT 13548
F+C CP GI QL G T
Sbjct: 1331 FSCACPTGI--QLKGDRKT 1347
Score = 93.2 bits (230), Expect = 2e-16
Identities = 56/188 (29%), Positives = 96/188 (50%), Gaps = 1/188 (0%)
Frame = +1
Query: 12952 DGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSP 13131
DG K ++ L +P A+ P G + ++D G AKIE A++DG+ R++++ + P
Sbjct: 1458 DGSCRKVLINNSLDEPRAIAVFPRKGYLFWTDWGHIAKIERANLDGSERKVLINTDLGWP 1517
Query: 13132 TSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSRES 13311
+ +D RIYWVD R+++ +++G R +V P+A+ + IYW ++
Sbjct: 1518 NGLTLDYDT-RRIYWVDAHLDRIESADLNGKLRQVLVSHVSHPFALTQQDRWIYWTDWQT 1576
Query: 13312 KTLYVQDKF-GRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPST 13488
K++ DK+ GR + +VLA+ +G + + T G C+HLC + S
Sbjct: 1577 KSIQRVDKYSGRNKETVLAN--VEGLMDIIVVSPQRQTGTNACGVNNGGCTHLCFARAS- 1633
Query: 13489 GFACLCPD 13512
F C CPD
Sbjct: 1634 DFVCACPD 1641
Score = 64.7 bits (156), Expect = 6e-08
Identities = 51/201 (25%), Positives = 76/201 (37%), Gaps = 17/201 (8%)
Frame = +1
Query: 139 NTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTYTWHS 318
N +S+C FRC G+C+R W
Sbjct: 264 NCTTSMCTAEQFRCRSGRCVRLSW------------------------------------ 287
Query: 319 VSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCR 498
RCD DCAD SDE++C + + + F+C +GR C K C+G DC
Sbjct: 288 --------RCDGEDDCADNSDEENCENTGSPQCASDQFLCWNGR-CIGQRKLCNGINDCG 338
Query: 499 DLSDE-----------KDSCSRNHTACFQYQFRCADKTQCIQKSW--VCDGSKDCADGSD 639
D SDE +++C+ N+ C Q QC + + + + + C D ++
Sbjct: 339 DSSDESPQQNCRPRTGEENCNVNNGGCAQKCQMVRGAVQCTRHTGYRLTEDGRTCQDVNE 398
Query: 640 --EPDTCEFKKCTANE--FQC 690
E C + CT E FQC
Sbjct: 399 CAEEGYCS-QGCTNTEGAFQC 418
Score = 62.8 bits (151), Expect = 2e-07
Identities = 56/197 (28%), Positives = 75/197 (37%), Gaps = 13/197 (6%)
Frame = +1
Query: 10753 PCGDNNGGCSH-LCLIGAGGNGYTCSCPDQFVLLSDQKTCEPN--CTERQFACGGDDAKC 10923
PC C++ C++ Y C D SD+ C + C +F C D C
Sbjct: 190 PCNLEEFQCAYGRCILDI----YHCDGDDDCGDWSDESDCSSHQPCRSGEFMC--DSGLC 243
Query: 10924 IPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXX 11103
I W CDG+ DC D SDE C +C +F+C + C R
Sbjct: 244 INSGWRCDGDADCDDQSDERN---CTTSMCTAEQFRCRSGRCVRLSWRCDGEDDCADNSD 300
Query: 11104 EQNCDKACDPWMFKCAA------TGRCIPRRFTXXXXXXXXXRSDEADTLCMSAERNC-- 11259
E+NC+ P +CA+ GRCI +R SDE S ++NC
Sbjct: 301 EENCENTGSP---QCASDQFLCWNGRCIGQRKLCNGINDCGDSSDE------SPQQNCRP 351
Query: 11260 -TAEE-FRCNNNKCIAK 11304
T EE NN C K
Sbjct: 352 RTGEENCNVNNGGCAQK 368
Score = 48.5 bits (114), Expect = 0.005
Identities = 29/106 (27%), Positives = 56/106 (52%), Gaps = 3/106 (2%)
Frame = +1
Query: 12988 LQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNR 13167
++ A+ P G++ +SD+ LH +I A +DG+ + I+ + + +A+D G +
Sbjct: 1080 MKNTIAIGVDPLEGKVYWSDSTLH-RISRASLDGSQHEDIITTGLQTTDGLAVD-AIGRK 1137
Query: 13168 IYWVDPKYRRVDAVNIDGSERTTVV-HDRHIPYAVDVFE--NHIYW 13296
+YW D R++ N+DGS R +V + P A+ ++ +YW
Sbjct: 1138 VYWTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYW 1183
Score = 38.9 bits (89), Expect = 3.7
Identities = 24/93 (25%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
Frame = +1
Query: 13027 GRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDA 13206
G++ Y+D L I AD++G++ + ++ + + +A+D N +YW D ++A
Sbjct: 1397 GKVYYTDVFLDV-IRRADLNGSNMETVIGHGLKTTDGLAVDWVARN-LYWTDTGRNTIEA 1454
Query: 13207 VNIDGSERTTVVHDR-HIPYAVDVF--ENHIYW 13296
+DGS R ++++ P A+ VF + +++W
Sbjct: 1455 SRLDGSCRKVLINNSLDEPRAIAVFPRKGYLFW 1487
>gi|37541633|ref|XP_035037.3| low density lipoprotein receptor-related
protein 4 [Homo sapiens]
Length = 1848
Score = 667 bits (1722), Expect = 0.0
Identities = 492/1737 (28%), Positives = 786/1737 (44%), Gaps = 34/1737 (1%)
Frame = +1
Query: 3181 FQCKNGRCIPKEWKCDGENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKKCIPAQXX 3360
F C NG+CI + W CDG+NDC D+SDE D C P +
Sbjct: 27 FHCDNGKCIRRSWVCDGDNDCEDDSDEQD------------------------CPPRE-- 60
Query: 3361 XXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNHRCIPEQWKXXXXXXXXXXXXEKLE 3540
C +F C N CI W E+ +
Sbjct: 61 -------------------------CEEDEFPCQNGYCIRSLWHCDGDNDCGDNSDEQCD 95
Query: 3541 MCGNATCAANQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERCPPV----QCSALQFRCA 3708
M C+ +F C++G CI +W CDGD DC DG+DE E CP C+ +F+CA
Sbjct: 96 M---RKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDE--ENCPSAVPAPPCNLEEFQCA 150
Query: 3709 NGR------QCVPLRNHXXXXXXXXXXXXXXXXAVTAESCTPDQFKCVSSGLCIPASWKX 3870
GR C + + + C +F C SGLCI A W+
Sbjct: 151 YGRCILDIYHCDGDDDCGDWSDESDCCEYSGQLGASHQPCRSGEFMC-DSGLCINAGWRC 209
Query: 3871 XXXXXXXXXSDEPKFGCTSGRQCSSDQFKCGNGRCILNNWLCDGENDCGDGSDESSERGC 4050
SDE R C QF+C +GRC+ +W CDGE+DC D SDE + C
Sbjct: 210 DGDADCDDQSDE--------RNCK--QFRCHSGRCVRLSWRCDGEDDCADNSDEEN---C 256
Query: 4051 KTSMNARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEGG------RCARDLCSAD 4212
+ + + +C + C N + CI +LC+G C +DE R + C+ +
Sbjct: 257 ENT-GSPQCALDQFLCWNGR--CIGQRKLCNGVNDCGDNSDESPQQNCRPRTGEENCNVN 313
Query: 4213 RAGCSFKCHNSPNGPICSCPFGEQLVNKTK-CEPENECLDSSSCSQRCKDEKHGFTCSCD 4389
GC+ KC C+C G +L C+ NEC + CSQ C + + F C C+
Sbjct: 314 NGGCAQKCQMVRGAVQCTCHTGYRLTEDGHTCQDVNECAEEGYCSQGCTNSEGAFQCWCE 373
Query: 4390 EGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHTFGAIVENAIALAWDSLT 4569
GYEL D+R+CK + + +NR I + +ENAIAL +
Sbjct: 374 TGYELRPDRRSCKALG--PEPVLLFANRIDIRQVLPHRSEYTLLLNNLENAIALDFHHRR 431
Query: 4570 DRIYWSDIREKKILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVDSSLNTIEVAN 4749
+ ++WSD+ +IL AN NG+N ++ GL+ G+A+DWV LYW DS + IEVAN
Sbjct: 432 ELVFWSDVTLDRILRANLNGSNVEEVVSTGLESPGGLAVDWVHDKLYWTDSGTSRIEVAN 491
Query: 4750 LEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQNPCIERASMDGTDRQIIVKTKIY 4929
L D R +L+ QN+ +PR IA+ P +G ++WTDWG P IE +SMDG+ R+II T ++
Sbjct: 492 L-DGAHRKVLLWQNLEKPRAIALHPMEGTIYWTDWGNTPRIEASSMDGSGRRIIADTHLF 550
Query: 4930 WPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKFVQHPHALAIFEDMMYYS 5109
WPN + +DY R+Y+ D+K I+ N DGS R V++ +FED +Y++
Sbjct: 551 WPNGLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVISQ-----------VFEDSLYWT 599
Query: 5110 DRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVIKNNPCSTN--PCSHLCL 5283
D + + K+ G E + + + +HP QP KN C N C+HLCL
Sbjct: 600 DWHTKSINSANKF-TGKNQEIIRNKLHFPMDIHTLHPQRQPAGKNR-CGDNNGGCTHLCL 657
Query: 5284 LNNKNTFTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNVFGIEMNSASEKETPVLAGMV 5463
+ +N +TC CP G + S C FL+ ++ ++ I ++ + ++
Sbjct: 658 PSGQN-YTCACPTGFR-KISSHACAQSLDKFLLFARRMDIRRISFDTEDLSD-----DVI 710
Query: 5464 PLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNGGNKTKMFSSAVP 5643
PL+ + +A +D+ + ++ ++TD+ I R+ +G + + +++
Sbjct: 711 PLADVRSAVALDWDSRDDHVY----------WTDVSTDT-ISRAKWDGTGQEVVVDTSLE 759
Query: 5644 DDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVILSNDQSXXXXXXXXXXXXXXX 5823
A L DW L + T IE+ T G +I N
Sbjct: 760 SPA-GLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWEN------LDRPRDIVVEPM 812
Query: 5824 KGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIAIDTTNTRVYFSEAKAGR 6003
GY++W D G A K+ RAG+D S VI S++L + +AID + R+Y+++A
Sbjct: 813 GGYMYWTDWG---ASPKIERAGMDASGRQVIISSNLTWPNGLAIDYGSQRLYWADAGMKT 869
Query: 6004 ISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAFDSIEVA-TINGDSQPPQWTHF 6180
I DG R ++ P GL YG+R+++ D SI+ A + G +
Sbjct: 870 IEFAGLDGSKRKVLIGSQLPHPFGLTLYGERIYWTDWQTKSIQSADRLTGLDRET----L 925
Query: 6181 KKDVENLANIKALQPRASSSGHPCHINNGNCDHICI----PLMFAQRTCTCANG--YVKD 6342
++++ENL +I R PC + NG C H+C+ P F +CTC G + D
Sbjct: 926 QENLENLMDIHVFHRRRPPVSTPCAMENGGCSHLCLRSPNPSGF---SCTCPTGINLLSD 982
Query: 6343 GQTSCKLFDESFVIVATKTKVIGYPIDETQSKGVAME-PIGGLSITGVDYDYESKTIYVA 6519
G+T C SF+I A + + +D V + I + + D + +Y +
Sbjct: 983 GKT-CSPGMNSFLIFARRIDIRMVSLDIPYFADVVVPINITMKNTIAIGVDPQEGKVYWS 1041
Query: 6520 EASGINKGITAYTIGESSPRAVIRDSIGSLTIKSLAIDWINYNMYFINHDAERTNIEVSK 6699
+++ I+ + S +I + G T LA+D I +Y+ D IEV
Sbjct: 1042 DST--LHRISRANLDGSQHEDII--TTGLQTTDGLAVDAIGRKVYWT--DTGTNRIEVGN 1095
Query: 6700 LDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQKPTIQRSFLDGSRREVIVSSGIAE 6879
LDG+ RK+L+ ++P +I + ++YW D G+ ++RS +DGS R V++++ +
Sbjct: 1096 LDGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTDWGENAKLERSGMDGSDRAVLINNNLGW 1155
Query: 6880 PTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPELVRSDIASAAGVALHGQNMYWTDNRL 7059
P L VD AS + W+DA + I G + S + G+ L +YWTD +
Sbjct: 1156 PNGLTVDKASSQLLWADAHTERIEAADLNGANRHTLVSPVQHPYGLTLLDSYIYWTDWQT 1215
Query: 7060 EKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSNNQPRASSPCQITDNLRKSPCTQ 7239
+ RA +L V ++L + D+ QP + C R C+
Sbjct: 1216 RSIHRADKGTGSNVIL-----VRSNLPGLMDMQAV-DRAQPLGFNKC----GSRNGGCSH 1265
Query: 7240 LCFATPGTQTPTCSCARGV-LK--GRTCE-EPDTYIMFSDGDKIIDVAIEPDVKASRPLK 7407
LC P +C+C G+ LK G+TC+ P+TY++FS I +++ D +
Sbjct: 1266 LCLPRPSGF--SCACPTGIQLKGDGKTCDPSPETYLLFSSRGSIRRISL--DTSDHTDVH 1321
Query: 7408 DPFPEISNLQTFDVDVNLRRVYFVVESPVGVNISWFSMNNAENPRLVFGASKQPHAKEIR 7587
P PE++N+ + D D +VY+ + V +++ + N N V G + ++
Sbjct: 1322 VPVPELNNVISLDYDSVDGKVYY---TDVFLDVIRRADLNGSNMETVIG-------RGLK 1371
Query: 7588 HISDMKLDWLTQKIYFT-TGRGG-KVMAIDTAGEHLSTIASGDWTYALAIDPCSGLLFWS 7761
+ +DW+ + +Y+T TGR + +D + + S D A+A+ P G LFW+
Sbjct: 1372 TTDGLAVDWVARNLYWTDTGRNTIEASRLDGSCRKVLINNSLDEPRAIAVFPRKGYLFWT 1431
Query: 7762 DSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVDFRNQKIYWADVNRLNIEV 7941
D G+ +IER+NL G RKV+++ + P + +D+ ++IYW D + IE
Sbjct: 1432 DWGHIA-------KIERANLDGSERKVLINTDLGWPNGLTLDYDTRRIYWVDAHLDRIES 1484
Query: 7942 ADYDGQNRKVIASGY-RAKSLDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVSDRRIPG 8118
AD +G+ R+V+ S +L DRW+Y +D + + R+DK SG E V+++ + G
Sbjct: 1485 ADLNGKLRQVLVSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVLAN--VEG 1542
Query: 8119 ALRVFASESDVRTRNQVCNALTSQLCKTDNGGCDQLCTVVADDIGLAASKVQCSCND 8289
+ + +T C +NGGC LC A D C+C D
Sbjct: 1543 LMDIIVVSPQRQTGTNACG--------VNNGGCTHLCFARASDF-------VCACPD 1584
Score = 435 bits (1118), Expect = e-119
Identities = 312/1041 (29%), Positives = 466/1041 (43%), Gaps = 62/1041 (5%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDT-----YTWH-- 315
C+ DF C++GKCIR W P C+ D++ C WH
Sbjct: 22 CSPLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPCQNGYCIRSLWHCD 81
Query: 316 --------------------------SVSCIAEYQRCDNITDCADGSDEKDCPASTV--D 411
SCIAE+ CD TDC DGSDE++CP++
Sbjct: 82 GDNDCGDNSDEQCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEENCPSAVPAPP 141
Query: 412 CSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCS------RNHTACFQYQFRCAD 573
C+ + F CA GR D+ CDG DC D SDE D C +H C +F C D
Sbjct: 142 CNLEE-FQCAYGRCILDIYH-CDGDDDCGDWSDESDCCEYSGQLGASHQPCRSGEFMC-D 198
Query: 574 KTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDN 753
CI W CDG DC D SDE + C +F+C + RC +RCD DDC DN
Sbjct: 199 SGLCINAGWRCDGDADCDDQSDE------RNC--KQFRCHSGRCVRLSWRCDGEDDCADN 250
Query: 754 SDEDEC---GEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLG-- 918
SDE+ C G +C ++ C G CI Q KLC+G DC D +DE QN P G
Sbjct: 251 SDEENCENTGSPQCALDQFLC-WNGRCIGQRKLCNGVNDCGDNSDESP-QQNCRPRTGEE 308
Query: 919 --------CQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPG 1074
C C +CTC +GY+L + H TC D+NECAE GYC Q C N
Sbjct: 309 NCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTEDGH-TCQDVNECAEEGYCSQGCTNSEGA 367
Query: 1075 FTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVK 1254
F C C G + R C + + + LF A R + ++ P E
Sbjct: 368 FQCWC-----------ETGYELRPDRRSCKALGPEPVLLF-ANRIDIRQVLPHR-SEYTL 414
Query: 1255 KLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAV 1434
L + E +DF + +FW+D A+++ S ++++ L P LAV
Sbjct: 415 LLNNLENAIALDFHHRRELVFWSDVTLDRILRANLNG----SNVEEVVSTGLESPGGLAV 470
Query: 1435 DWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFT---NQLK 1605
DW+ + LY +SG+ RI+V++ DG R VLL L P IAL P+ G +++T N +
Sbjct: 471 DWVHDKLYWTDSGTSRIEVANLDGAHRKVLLWQNLEKPRAIALHPMEGTIYWTDWGNTPR 530
Query: 1606 LEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQG 1785
+EA++MDG+ RR + +TH +G+ +D +R+YWVD K +E + G+ R+ V
Sbjct: 531 IEASSMDGSGRRIIADTHLFWPNGLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVIS- 589
Query: 1786 MNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMA 1965
+F+ LYWTDW + KF + + N + FPM I HP
Sbjct: 590 ----------QVFEDSLYWTDWHTKSINSANKFTGKNQEIIRNKLH--FPMDIHTLHPQR 637
Query: 1966 QPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGKRCIDSI 2145
QP G++ C N C +C+ S G Y CACP G + ++ C S+
Sbjct: 638 QPA-GKNRC-------GDNNGGCTHLCLPS------GQNYTCACPTGFRKISSHACAQSL 683
Query: 2146 D-YLLFSSNKIVRGIFPEINEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIM 2322
D +LLF+ +R I + + L++ V+P++ + ++ D + ++ D+
Sbjct: 684 DKFLLFARRMDIRRI--SFDTEDLSDDVIPLADVRSA-----VALDWDSRDDHVYWTDVS 736
Query: 2323 DNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHP 2502
+TI R + DG G V+ T + ++ DW++ +LY+ D + +EV +
Sbjct: 737 TDTISRAKWDGTGQEVVVDTSLESPAGLAIDWVTNKLYWTDAGTDRIEV--------ANT 788
Query: 2503 DELVRRQLITELRD-PVSVVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRP 2679
D +R LI E D P +VV P G +++ + I R +D QVI ++ L P
Sbjct: 789 DGSMRTVLIWENLDRPRDIVVEPMGGYMYWTDWGASPKIERAGMDASGRQVIISSNLTWP 848
Query: 2680 SEMAIDFAENRLCWGDTLLKTISCMDFDG-KNVVKLDIDNPIPVAITIMNEYIYYVHQRP 2856
+ +AID+ RL W D +KTI DG K V + P P +T+ E IY+ +
Sbjct: 849 NGLAIDYGSQRLYWADAGMKTIEFAGLDGSKRKVLIGSQLPHPFGLTLYGERIYWTDWQT 908
Query: 2857 YSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIPDDSREHPCRASQ--CTQLC 3030
SI+ + G + ++E + ++ + + P+ PC C+ LC
Sbjct: 909 KSIQSADRLTGLDRETLQE---NLENLMDIHVFHRRRPPV-----STPCAMENGGCSHLC 960
Query: 3031 FATPSESHPNELEAKCACRQG 3093
+P+ S C C G
Sbjct: 961 LRSPNPS-----GFSCTCPTG 976
Score = 413 bits (1062), Expect = e-113
Identities = 250/726 (34%), Positives = 358/726 (48%), Gaps = 16/726 (2%)
Frame = +1
Query: 8725 LATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRC 8904
L TC L C K CI+ + +CDG +DC D +DE C ++C + C
Sbjct: 19 LPTCSPLDFHCDNGK--------CIRRSWVCDGDNDCEDDSDEQD--CPPRECEEDEFPC 68
Query: 8905 PSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXX 9084
+G CI W CDGDNDC D DE + C D F+C + CI+ +
Sbjct: 69 QNGYCIRSLWHCDGDNDCGDNSDEQ-------CDMRKC-SDKEFRCSDGSCIAEHWYCDG 120
Query: 9085 XXXXXXXXXXHSRHGCGNRT----CTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAG 9252
C + C +EF C CI + CDGD C
Sbjct: 121 DTDCKDGS---DEENCPSAVPAPPCNLEEFQCAYG--------RCILDIYHCDGDDDCGD 169
Query: 9253 GEDESTELCK------TEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYS 9414
DES + C+ + C GEF C + CI++ W CDGD DC D SDE NC
Sbjct: 170 WSDES-DCCEYSGQLGASHQPCRSGEFMCDSGLCINAGWRCDGDADCDDQSDER-NCKQ- 226
Query: 9415 SCQPDFFQCANHKCVPNSWKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTSGE 9594
F+C + +CV SW+CDG DDC D SDE++C +N+ S Q C+ QF C +G
Sbjct: 227 ------FRCHSGRCVRLSWRCDGEDDCADNSDEENC-ENTGSPQ----CALDQFLCWNGR 275
Query: 9595 CIDDAKVCDRNFDCTDRSDESSLCFI------DECSLAEKPLCEQKCMDMKIGYKCDCFE 9756
CI K+C+ DC D SDES + C++ C QKC ++ +C C
Sbjct: 276 CIGQRKLCNGVNDCGDNSDESPQQNCRPRTGEENCNVNNGG-CAQKCQMVRGAVQCTCHT 334
Query: 9757 GFAIDISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEP 9936
G+ + D +C +VNEC E CSQ C + G+++C C GY+L D SCK + P
Sbjct: 335 GYRLT-EDGHTCQDVNECAEE-GYCSQGCTNSEGAFQCWCETGYELRPDRRSCKA--LGP 390
Query: 9937 EPFFLLANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLD 10116
EP L AN+ IR++ ++Y L +N ++LD + + D R+LR +L+
Sbjct: 391 EPVLLFANRIDIRQVLPHRSEYTLLLNNLENAIALDFHHRRELVFWSDVTLDRILRANLN 450
Query: 10117 EMDSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRI 10296
S+ E V+ + G+AVDWV KLY + I V LDG K L+ +
Sbjct: 451 G-----SNVEEVVSTGLESPGGLAVDWVHDKLYWTDSGTSRIEVANLDGAHRKVLLWQNL 505
Query: 10297 QQPKAIVVHPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYF 10476
++P+AI +HP +G +++T+W P I ++DGS +A+ L WPN + IDY
Sbjct: 506 EKPRAIALHPMEGTIYWTDWGNTPRIEASSMDGSGRRI-----IADTHLFWPNGLTIDYA 560
Query: 10477 SDRLFWGDAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDK 10656
R++W DA + I + DG+ R+ + +Q VF+D LYW DW+ + + +K
Sbjct: 561 GRRMYWVDAKHHVIERANLDGSHRKAVISQ---------VFEDSLYWTDWHTKSINSANK 611
Query: 10657 WTGKNETILKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPD 10836
+TGKN+ I++ + P D+ +HP RQPA N CGDNNGGC+HLCL G YTC+CP
Sbjct: 612 FTGKNQEIIRNKLHFPMDIHTLHPQRQPAGKNRCGDNNGGCTHLCL--PSGQNYTCACPT 669
Query: 10837 QFVLLS 10854
F +S
Sbjct: 670 GFRKIS 675
Score = 304 bits (779), Expect = 4e-80
Identities = 228/787 (28%), Positives = 329/787 (40%), Gaps = 16/787 (2%)
Frame = +1
Query: 11233 LCMSAERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXETPECAQIECKKGWTRCSSSY 11412
LC C+ +F C+N KCI ++W
Sbjct: 14 LCAHVLPTCSPLDFHCDNGKCIRRSW---------------------------------- 39
Query: 11413 RCIPNWAFCNGQDDCRDNSDEDKQRCPT--CDDVGEFRCATSGKCIPRRWMCDTENDCGD 11586
C+G +DC D+SDE Q CP C++ EF C +G CI W CD +NDCGD
Sbjct: 40 -------VCDGDNDCEDDSDE--QDCPPRECEE-DEFPCQ-NGYCIRSLWHCDGDNDCGD 88
Query: 11587 NSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTLR----RCL 11754
NSDE C R CS+ EFRC+DG CI CDG C DG DE C C
Sbjct: 89 NSDE---QCD--MRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEENCPSAVPAPPCN 143
Query: 11755 PGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCED------VSRRTCSPFEFECANSVCI 11916
QC G CI + CD DC + +DE C + S + C EF C + +CI
Sbjct: 144 LEEFQCAYGRCILDIYHCDGDDDCGDWSDESDCCEYSGQLGASHQPCRSGEFMCDSGLCI 203
Query: 11917 PRKFMXXXXXXXXXXSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPNDF 12096
+ SDE + + +FRC HS C+ + C+G +DC N
Sbjct: 204 NAGWRCDGDADCDDQSDERNCK----------QFRC-HSGRCVRLSWRCDGEDDCADN-- 250
Query: 12097 SDEHLSMCSSFSEYGDCSSDQFKCANGKCVNGTVACDRKDDCGDASDEI---GCSKHGGK 12267
SDE C + C+ DQF C NG+C+ C+ +DCGD SDE C G+
Sbjct: 251 SDEE--NCENTGS-PQCALDQFLCWNGRCIGQRKLCNGVNDCGDNSDESPQQNCRPRTGE 307
Query: 12268 TSCEAFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLCLNT 12447
+C NNGGC C VR C C G+R + C D++ECA C+Q C N+
Sbjct: 308 ENCNV--NNGGCAQKCQMVRGAVQCTCHTGYRLT-EDGHTCQDVNECAEEGYCSQGCTNS 364
Query: 12448 KGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGSGTNRHXXXX 12627
+G++ C C YE + C+A G ++ + Q+ H R
Sbjct: 365 EGAFQCWCETGYELR-----PDRRSCKALGPEPVLLFANRIDIRQVLPH-----RSEYTL 414
Query: 12628 XXXXXXXXXXXXXXPRKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTA 12807
R+EL++W S+ T+ R AN N S+ + + + P
Sbjct: 415 LLNNLENAIALDFHHRRELVFW---SDVTLDRILRANLNGSNVEEVVSTGLES----PGG 467
Query: 12808 IAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGH 12987
+AVD+ L+ + T I V DG + K ++ +
Sbjct: 468 LAVDWVHDKLYWT-----------------------DSGTSRIEVANLDGAHRKVLLWQN 504
Query: 12988 LQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNR 13167
L++P A+ P G I ++D G +IE + MDG+ R+II +F P + ID G R
Sbjct: 505 LEKPRAIALHPMEGTIYWTDWGNTPRIEASSMDGSGRRIIADTHLFWPNGLTIDYA-GRR 563
Query: 13168 IYWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSRESKTLYVQDKFGRG 13347
+YWVD K+ ++ N+DGS R V+ VFE+ +YW +K++ +KF
Sbjct: 564 MYWVDAKHHVIERANLDGSHRKAVIS--------QVFEDSLYWTDWHTKSINSANKFTGK 615
Query: 13348 RVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPS-TGFACLCPDGIVP 13524
++ + L + + + G C+HLC LPS + C CP G
Sbjct: 616 NQEIIRNKLHFPMDIHTLHPQRQPAGKNRCGDNNGGCTHLC--LPSGQNYTCACPTGFRK 673
Query: 13525 QLDGSCA 13545
+CA
Sbjct: 674 ISSHACA 680
Score = 244 bits (624), Expect = 3e-62
Identities = 195/732 (26%), Positives = 335/732 (45%), Gaps = 12/732 (1%)
Frame = +1
Query: 1018 NECAEF-GYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLF 1194
N C + G C LC +TC+C G K + + + + DK LF
Sbjct: 643 NRCGDNNGGCTHLCLPSGQNYTCAC---------PTGFRK----ISSHACAQSLDKFLLF 689
Query: 1195 VARREGLYRLNPKNPD--EEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDE 1368
ARR + R++ D ++V LA +D+D D ++WTD + A D
Sbjct: 690 -ARRMDIRRISFDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDGT 748
Query: 1369 GEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLP 1548
G+ + SL+S P LA+DW+TN LY ++G+ RI+V++ DG RTVL+ + L P
Sbjct: 749 GQ-EVVVDTSLES---PAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRP 804
Query: 1549 LDIALDPLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVD 1719
DI ++P+ G M++T+ K+E A MD + R+ +++++ +G+ +D ++R+YW D
Sbjct: 805 RDIVVEPMGGYMYWTDWGASPKIERAGMDASGRQVIISSNLTWPNGLAIDYGSQRLYWAD 864
Query: 1720 PKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKF-GSDT 1896
+ +E G+ R+++ +PHPFGL L+ + +YWTDW + ++ G D
Sbjct: 865 AGMKTIEFAGLDGSKRKVLIGSQ--LPHPFGLTLYGERIYWTDWQTKSIQSADRLTGLDR 922
Query: 1897 KLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCT--NADCEGMCILSKDNGG 2070
+ L N EN M I +H P + PC N C +C+ S + G
Sbjct: 923 ETLQENLEN---LMDIHVFHRRRPP-----------VSTPCAMENGGCSHLCLRSPNPSG 968
Query: 2071 FGVGYKCACPIGQKLV-NGKRCIDSID-YLLFSSNKIVRGIFPEINEKALAEAVLPISPI 2244
F C CP G L+ +GK C ++ +L+F+ +R + +I A+ V+PI+
Sbjct: 969 F----SCTCPTGINLLSDGKTCSPGMNSFLIFARRIDIRMVSLDI--PYFADVVVPINIT 1022
Query: 2245 SQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWIS 2424
+ I + D +++D + I R DG ++ T ++ D I
Sbjct: 1023 MKNTIA----IGVDPQEGKVYWSDSTLHRISRANLDGSQHEDIITTGLQTTDGLAVDAIG 1078
Query: 2425 KQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITE-LRDPVSVVVHPWKGLLFYAEAM 2601
+++Y+ D N +EV + D +R+ L+ + L P ++V++ G +++ +
Sbjct: 1079 RKVYWTDTGTNRIEVGNL--------DGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTDWG 1130
Query: 2602 RPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVK 2781
A + R +DG + V+ N LG P+ + +D A ++L W D + I D +G N
Sbjct: 1131 ENAKLERSGMDGSDRAVLINNNLGWPNGLTVDKASSQLLWADAHTERIEAADLNGANRHT 1190
Query: 2782 LDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSH 2961
L P +T+++ YIY+ + SI R K G +VR ++ L
Sbjct: 1191 LVSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKGTGSNVILVRS------NLPGLMDMQA 1244
Query: 2962 QNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINKENNHSCQKDPA 3141
++ P + R C+ LC PS CAC G + K + +C DP+
Sbjct: 1245 VDRAQPLGFNKCGSRNGGCSHLCLPRPS-------GFSCACPTGIQL-KGDGKTC--DPS 1294
Query: 3142 EKIEQLCSSNST 3177
+ L SS +
Sbjct: 1295 PETYLLFSSRGS 1306
Score = 228 bits (580), Expect = 4e-57
Identities = 195/701 (27%), Positives = 315/701 (44%), Gaps = 16/701 (2%)
Frame = +1
Query: 994 FHRTCSDINE-CA-EFGYCDQLCAN--HRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYC 1161
FHR ++ CA E G C LC + GF+C+C P NL G
Sbjct: 938 FHRRRPPVSTPCAMENGGCSHLCLRSPNPSGFSCTC------------PTGINLLSDGKT 985
Query: 1162 VSNNADKMKLFVARREGLYRLN---PKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRL 1332
S + +F ARR + ++ P D V + + I D + K++W+D
Sbjct: 986 CSPGMNSFLIF-ARRIDIRMVSLDIPYFADVVVPINITMKNTIAIGVDPQEGKVYWSDST 1044
Query: 1333 AHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGER 1512
H A++D SQ + + L LAVD I +Y ++G+ RI+V + DG
Sbjct: 1045 LHRISRANLDG----SQHEDIITTGLQTTDGLAVDAIGRKVYWTDTGTNRIEVGNLDGSM 1100
Query: 1513 RTVLLADGLTLPLDIALDPLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHTHQVSGIV 1683
R VL+ L P I L G M++T+ KLE + MDG++R L+N + +G+
Sbjct: 1101 RKVLVWQNLDSPRAIVLYHEMGFMYWTDWGENAKLERSGMDGSDRAVLINNNLGWPNGLT 1160
Query: 1684 VDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLG 1863
VD + ++ W D +R+E+ D G +R + ++ V HP+GL L D Y+YWTDW
Sbjct: 1161 VDKASSQLLWADAHTERIEAADLNGANRHTL---VSPVQHPYGLTLLDSYIYWTDWQTRS 1217
Query: 1864 VIQVEK-FGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEG 2040
+ + +K GS+ L+ SN + + P+ G ++C + N C
Sbjct: 1218 IHRADKGTGSNVILVRSNLPGLMDMQAVDRAQPL-----GFNKCGSR-------NGGCSH 1265
Query: 2041 MCILSKDNGGFGVGYKCACPIGQKLV-NGKRCIDSID-YLLFSSNKIVRGIFPEINEKAL 2214
+C+ G+ CACP G +L +GK C S + YLLFSS +R I + ++
Sbjct: 1266 LCLPRPS------GFSCACPTGIQLKGDGKTCDPSPETYLLFSSRGSIRRISLDTSDHTD 1319
Query: 2215 AEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDG 2394
+P + ++ D +Y D+ + I R +G V+
Sbjct: 1320 VHVPVP-------ELNNVISLDYDSVDGKVYYTDVFLDVIRRADLNGSNMETVIGRGLKT 1372
Query: 2395 LFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITE-LRDPVSVVVHPW 2571
++ DW+++ LY+ D RN++E ++ D R+ LI L +P ++ V P
Sbjct: 1373 TDGLAVDWVARNLYWTDTGRNTIEASRL--------DGSCRKVLINNSLDEPRAIAVFPR 1424
Query: 2572 KGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISC 2751
KG LF+ + A I R ++DG +V+ NT LG P+ + +D+ R+ W D L I
Sbjct: 1425 KGYLFWTDWGHIAKIERANLDGSERKVLINTDLGWPNGLTLDYDTRRIYWVDAHLDRIES 1484
Query: 2752 MDFDGKNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADER 2931
D +GK L P A+T + +IY+ + SI+RV K +G + V A+
Sbjct: 1485 ADLNGKLRQVLVSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVL---ANVE 1541
Query: 2932 SIFSLKACSHQNQPIPDDSREHPCRASQ--CTQLCFATPSE 3048
+ + S Q Q + + C + CT LCFA S+
Sbjct: 1542 GLMDIIVVSPQRQ-----TGTNACGVNNGGCTHLCFARASD 1577
Score = 225 bits (574), Expect = 2e-56
Identities = 125/349 (35%), Positives = 184/349 (51%), Gaps = 3/349 (0%)
Frame = +1
Query: 9802 NECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKI 9981
N+C GCS C + + C C G QL D +C + PE + L +++ IR+I
Sbjct: 1254 NKCGSRNGGCSHLCLPRPSGFSCACPTGIQLKGDGKTC---DPSPETYLLFSSRGSIRRI 1310
Query: 9982 SIDGNKY---ELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETV 10152
S+D + + + +NV+SLD D + K Y D + R DL+ S+ ETV
Sbjct: 1311 SLDTSDHTDVHVPVPELNNVISLDYDSVDGKVYYTDVFLDVIRRADLNG-----SNMETV 1365
Query: 10153 LRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGK 10332
+ + T+G+AVDWV R LY + +I LDG K LI + + +P+AI V P K
Sbjct: 1366 IGRGLKTTDGLAVDWVARNLYWTDTGRNTIEASRLDGSCRKVLINNSLDEPRAIAVFPRK 1425
Query: 10333 GYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLN 10512
GYLF+T+W I R LDGS L DLGWPN + +DY + R++W DAHL+
Sbjct: 1426 GYLFWTDWGHIAKIERANLDGSERK-----VLINTDLGWPNGLTLDYDTRRIYWVDAHLD 1480
Query: 10513 EIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKT 10692
I D +G R + SH ++ D ++YW DW + + R DK++G+N+ +
Sbjct: 1481 RIESADLNGK-LRQVLVSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVLAN 1539
Query: 10693 VQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQ 10839
V+ D+ +V P RQ N CG NNGGC+HLC A + + C+CPD+
Sbjct: 1540 VEGLMDIIVVSPQRQTG-TNACGVNNGGCTHLCF--ARASDFVCACPDE 1585
Score = 201 bits (510), Expect = 6e-49
Identities = 113/361 (31%), Positives = 174/361 (47%), Gaps = 3/361 (0%)
Frame = +1
Query: 9802 NECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKI 9981
N C + GC+ C +Y C C G++ S H+C ++ + F L A + IR+I
Sbjct: 643 NRCGDNNGGCTHLCLPSGQNYTCACPTGFRKISS-HACAQSL---DKFLLFARRMDIRRI 698
Query: 9982 SIDGNKYE---LAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETV 10152
S D + + V+LD D + Y D + R D + E V
Sbjct: 699 SFDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDG-----TGQEVV 753
Query: 10153 LRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGK 10332
+ ++ G+A+DWV KLY + I V DG LI + + +P+ IVV P
Sbjct: 754 VDTSLESPAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRPRDIVVEPMG 813
Query: 10333 GYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLN 10512
GY+++T+W P I R +D S + +L WPN +AIDY S RL+W DA +
Sbjct: 814 GYMYWTDWGASPKIERAGMDASGRQV-----IISSNLTWPNGLAIDYGSQRLYWADAGMK 868
Query: 10513 EIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKT 10692
I F DG+ R+ + + H + ++ + +YW DW + + D+ TG + L++
Sbjct: 869 TIEFAGLDGSKRKVLIGSQLPHPFGLTLYGERIYWTDWQTKSIQSADRLTGLDRETLQEN 928
Query: 10693 VQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTCE 10872
++ D+ + H R+P PC NGGCSHLCL +G++C+CP LLSD KTC
Sbjct: 929 LENLMDIHVFH-RRRPPVSTPCAMENGGCSHLCLRSPNPSGFSCTCPTGINLLSDGKTCS 987
Query: 10873 P 10875
P
Sbjct: 988 P 988
Score = 194 bits (494), Expect = 4e-47
Identities = 114/357 (31%), Positives = 171/357 (46%), Gaps = 6/357 (1%)
Frame = +1
Query: 9826 GCSQKC--DDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNK 9999
GCS C + C C G L SD +C F + A + IR +S+D
Sbjct: 955 GCSHLCLRSPNPSGFSCTCPTGINLLSDGKTCSPGM---NSFLIFARRIDIRMVSLDIPY 1011
Query: 10000 YELAAQGFD----NVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNV 10167
+ + N +++ +D E K Y D R+ R +LD S +E ++ +
Sbjct: 1012 FADVVVPINITMKNTIAIGVDPQEGKVYWSDSTLHRISRANLDG-----SQHEDIITTGL 1066
Query: 10168 YGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFF 10347
T+G+AVD +GRK+Y + I V LDG K L+ + P+AIV++ G++++
Sbjct: 1067 QTTDGLAVDAIGRKVYWTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYW 1126
Query: 10348 TEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFM 10527
T+W + R +DGS L ++LGWPN + +D S +L W DAH I
Sbjct: 1127 TDWGENAKLERSGMDGSDRA-----VLINNNLGWPNGLTVDKASSQLLWADAHTERIEAA 1181
Query: 10528 DFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPN 10707
D +G RH H + + D Y+YW DW R + R DK TG N +++ +
Sbjct: 1182 DLNG-ANRHTLVSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKGTGSNVILVRSNLPGLM 1240
Query: 10708 DLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTCEPN 10878
D++ V QP N CG NGGCSHLCL +G++C+CP L D KTC+P+
Sbjct: 1241 DMQAV-DRAQPLGFNKCGSRNGGCSHLCL--PRPSGFSCACPTGIQLKGDGKTCDPS 1294
Score = 154 bits (388), Expect = 8e-35
Identities = 115/379 (30%), Positives = 152/379 (39%), Gaps = 26/379 (6%)
Frame = +1
Query: 8383 PYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCN 8562
P +F C +G CI CD DC D SDE C R C ED C N CI S C+
Sbjct: 24 PLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQD--CPPRECEEDEFPCQNGYCIRSLWHCD 81
Query: 8563 HIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPG 8742
+DCGD SDE C C++ F CS+G CI + CDG DC D + + P
Sbjct: 82 GDNDCGDNSDE-QCDMR-KCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEENCPSAVPA 139
Query: 8743 LPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADEN-------QLFCMNQQCAQHYVR 8901
P C + +C CI CDG DDCGD +DE+ QL +Q C
Sbjct: 140 PP--CNLEEFQCAYGR-CILDIYHCDGDDDCGDWSDESDCCEYSGQLGASHQPCRSGEFM 196
Query: 8902 CPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXX 9081
C SG CI W+CDGD DC D DE NC F+C + +C+ ++
Sbjct: 197 CDSGLCINAGWRCDGDADCDDQSDE--RNCKQ------------FRCHSGRCVRLSWRCD 242
Query: 9082 XXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGED 9261
+ G+ C +F C + CI + LC+G C D
Sbjct: 243 GEDDCADNSDEENCENTGSPQCALDQFLCWNG--------RCIGQRKLCNGVNDCGDNSD 294
Query: 9262 ESTEL-C--KTEKKECNKGEFRCSN---------QHCIHSTWE-------CDGDNDCLDG 9384
ES + C +T ++ CN C+ Q H+ + C N+C +
Sbjct: 295 ESPQQNCRPRTGEENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTEDGHTCQDVNECAEE 354
Query: 9385 SDEHANCTYSSCQPDFFQC 9441
CT S FQC
Sbjct: 355 GYCSQGCTNSE---GAFQC 370
Score = 144 bits (363), Expect = 6e-32
Identities = 100/316 (31%), Positives = 130/316 (40%), Gaps = 11/316 (3%)
Frame = +1
Query: 10873 PNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCT 11052
P C+ F C D+ KCI + W CDG+ DC D SDE C R C EF C N C
Sbjct: 20 PTCSPLDFHC--DNGKCIRRSWVCDGDNDCEDDSDEQD---CPPRECEEDEFPCQNGYCI 74
Query: 11053 RPFQIXXXXXXXXXXXXEQNCDKACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEADT 11232
R EQ + C F+C + G CI + SDE +
Sbjct: 75 RSLWHCDGDNDCGDNSDEQCDMRKCSDKEFRC-SDGSCIAEHWYCDGDTDCKDGSDEENC 133
Query: 11233 LCMSAERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXETPEC--------AQIECKKG 11388
C EEF+C +CI + E+ C + C+ G
Sbjct: 134 PSAVPAPPCNLEEFQCAYGRCILDIYHCDGDDDCGDWSDESDCCEYSGQLGASHQPCRSG 193
Query: 11389 WTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATSGKCIPRRWMCDT 11568
C S W C+G DC D SDE + C +FRC SG+C+ W CD
Sbjct: 194 EFMCDSGLCINAGWR-CDGDADCDDQSDE--RNCK------QFRC-HSGRCVRLSWRCDG 243
Query: 11569 ENDCGDNSDELDASCGGTTRP-CSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTLR 11745
E+DC DNSDE +C T P C+ +F C +G+CI K+C+G C D DES
Sbjct: 244 EDDCADNSDE--ENCENTGSPQCALDQFLCWNGRCIGQRKLCNGVNDCGDNSDESPQQNC 301
Query: 11746 RCLPGHRQC--DDGTC 11787
R G C ++G C
Sbjct: 302 RPRTGEENCNVNNGGC 317
Score = 142 bits (357), Expect = 3e-31
Identities = 105/370 (28%), Positives = 174/370 (46%), Gaps = 9/370 (2%)
Frame = +1
Query: 1018 NEC-AEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLF 1194
N+C + G C LC GF+C+C +Q++ G GK + + + L
Sbjct: 1254 NKCGSRNGGCSHLCLPRPSGFSCACPTG---IQLK-GDGK---------TCDPSPETYLL 1300
Query: 1195 VARREGLYRLNPKNPDEEVKKLASGEF--IYGIDFDYGDRKIFWTDRLAHSAFSADVDDE 1368
+ R + R++ D + E + +D+D D K+++TD AD++
Sbjct: 1301 FSSRGSIRRISLDTSDHTDVHVPVPELNNVISLDYDSVDGKVYYTDVFLDVIRRADLNG- 1359
Query: 1369 GEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLP 1548
S ++ + + L LAVDW+ LY ++G I+ S DG R VL+ + L P
Sbjct: 1360 ---SNMETVIGRGLKTTDGLAVDWVARNLYWTDTGRNTIEASRLDGSCRKVLINNSLDEP 1416
Query: 1549 LDIALDPLRGEMFFTNQ---LKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVD 1719
IA+ P +G +F+T+ K+E A +DG+ R+ L+NT +G+ +D +R+YWVD
Sbjct: 1417 RAIAVFPRKGYLFWTDWGHIAKIERANLDGSERKVLINTDLGWPNGLTLDYDTRRIYWVD 1476
Query: 1720 PKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKF-GSDT 1896
+DR+ES D G R+++ ++ V HPF L D+++YWTDW + +V+K+ G +
Sbjct: 1477 AHLDRIESADLNGKLRQVL---VSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNK 1533
Query: 1897 KLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPC--TNADCEGMCILSKDNGG 2070
+ + +N E M I P Q G N C N C +C +
Sbjct: 1534 ETVLANVEG---LMDIIVVSPQRQTG-----------TNACGVNNGGCTHLCFARASD-- 1577
Query: 2071 FGVGYKCACP 2100
+ CACP
Sbjct: 1578 ----FVCACP 1583
Score = 140 bits (352), Expect = 1e-30
Identities = 107/343 (31%), Positives = 146/343 (42%), Gaps = 13/343 (3%)
Frame = +1
Query: 8362 PAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCI 8541
P +EC F C +G CI CD DC D SDE C+ R C + C++ CI
Sbjct: 57 PPRECEED-EFPCQNGYCIRSLWHCDGDNDCGDNSDEQ---CDMRKCSDKEFRCSDGSCI 112
Query: 8542 DSAKKCNHIDDCGDGSDELDCPSAV---ACAEGTFPCSNGHCINQTKVCDGHNDC---HD 8703
C+ DC DGSDE +CPSAV C F C+ G CI CDG +DC D
Sbjct: 113 AEHWYCDGDTDCKDGSDEENCPSAVPAPPCNLEEFQCAYGRCILDIYHCDGDDDCGDWSD 172
Query: 8704 EQVSDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQC 8883
E E CR + C ++ +CI CDG DC D++DE + C
Sbjct: 173 ESDCCEYSGQLGASHQPCRSGEFMC-DSGLCINAGWRCDGDADCDDQSDE-------RNC 224
Query: 8884 AQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCIS 9063
Q RC SGRC+ +W+CDG++DC+D DE NC +T + + +L C N +CI
Sbjct: 225 KQ--FRCHSGRCVRLSWRCDGEDDCADNSDE--ENCENTGSPQCALDQFL--CWNGRCIG 278
Query: 9064 RAFIXXXXXXXXXXXXXHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVT 9243
+ + + C RT E +C N K + + A C T
Sbjct: 279 QRKLCNGVNDCGDNSDESPQQNCRPRT---GEENCNVNNGGCAQKCQMVRGAVQC----T 331
Query: 9244 CAGGE--DESTELCK-----TEKKECNKGEFRCSNQHCIHSTW 9351
C G E C+ E+ C++G C+N W
Sbjct: 332 CHTGYRLTEDGHTCQDVNECAEEGYCSQG---CTNSEGAFQCW 371
Score = 127 bits (319), Expect = 8e-27
Identities = 102/353 (28%), Positives = 141/353 (39%), Gaps = 19/353 (5%)
Frame = +1
Query: 10852 SDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPG-ESICGQRICPVGEF 11028
SD++ C++++F C D CI + WYCDG+ DC+DGSDE S C + EF
Sbjct: 90 SDEQCDMRKCSDKEFRCS--DGSCIAEHWYCDGDTDCKDGSDEENCPSAVPAPPCNLEEF 147
Query: 11029 QCTNHNCTRPFQIXXXXXXXXXXXXEQNCDKACDPWMFKCAATGRCIPRRFTXXXXXXXX 11208
QC A GRCI +
Sbjct: 148 QC---------------------------------------AYGRCILDIYHCDGDDDCG 168
Query: 11209 XRSDEADTLCMSAE-----RNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXETPECAQI 11373
SDE+D S + + C + EF C++ CI WR E C Q
Sbjct: 169 DWSDESDCCEYSGQLGASHQPCRSGEFMCDSGLCINAGWRCDGDADCDDQSDER-NCKQF 227
Query: 11374 ECKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCAT------SG 11535
C G RC+ C+G+DDC DNSDE+ C++ G +CA +G
Sbjct: 228 RCHSG--------RCVRLSWRCDGEDDCADNSDEE-----NCENTGSPQCALDQFLCWNG 274
Query: 11536 KCIPRRWMCDTENDCGDNSDELDASCGGTTRP-CSESEFRCNDGKCIPGSKVCDGTIQCS 11712
+CI +R +C+ NDCGDNSDE S RP E N+G C ++ G +QC+
Sbjct: 275 RCIGQRKLCNGVNDCGDNSDE---SPQQNCRPRTGEENCNVNNGGCAQKCQMVRGAVQCT 331
Query: 11713 DGLDESQCTLRRCLPGHRQCDDG-TC-----IAEHKWCDRKKDCPNAADELHC 11853
C G+R +DG TC AE +C + C N+ C
Sbjct: 332 ------------CHTGYRLTEDGHTCQDVNECAEEGYC--SQGCTNSEGAFQC 370
Score = 122 bits (306), Expect = 3e-25
Identities = 78/261 (29%), Positives = 114/261 (42%), Gaps = 44/261 (16%)
Frame = +1
Query: 9274 LCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEH------------------- 9396
LC C+ +F C N CI +W CDGDNDC D SDE
Sbjct: 14 LCAHVLPTCSPLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPCQNGYC 73
Query: 9397 ------------------ANCTYSSCQPDFFQCANHKCVPNSWKCDGNDDCEDGSDEKDC 9522
C C F+C++ C+ W CDG+ DC+DGSDE++C
Sbjct: 74 IRSLWHCDGDNDCGDNSDEQCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEENC 133
Query: 9523 PKNSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLC-FIDECSLAEKP 9699
P SA A C+ +FQC G CI D CD + DC D SDES C + + + +P
Sbjct: 134 P----SAVPAPPCNLEEFQCAYGRCILDIYHCDGDDDCGDWSDESDCCEYSGQLGASHQP 189
Query: 9700 ------LCEQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNECYEGISGCSQKCDDKIGS 9861
+C+ + + G++CD + D SD+++C C+ G C + S
Sbjct: 190 CRSGEFMCDSG-LCINAGWRCD-GDADCDDQSDERNCKQF-RCHSG--RCVRL------S 238
Query: 9862 YKCGCVDGYQLSSDDHSCKRT 9924
++C D +SD+ +C+ T
Sbjct: 239 WRCDGEDDCADNSDEENCENT 259
Score = 105 bits (262), Expect = 3e-20
Identities = 92/382 (24%), Positives = 155/382 (40%), Gaps = 3/382 (0%)
Frame = +1
Query: 12400 DECAGNNT-CTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDSL 12576
+ C NN CT LCL + +Y C C + ++ C D + D +
Sbjct: 643 NRCGDNNGGCTHLCLPSGQNYTCACPTGFRK------ISSHACAQSLDKFLLFARRMD-I 695
Query: 12577 VQLSLHGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERTIYRSAIANGNQSHE 12756
++S + R + +YW D S TI R+
Sbjct: 696 RRISFDTEDLSDDVIPLADVRSAVALDWDS--RDDHVYWTDVSTDTISRA-----KWDGT 748
Query: 12757 GQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFI 12936
GQ++ VD + P +A+D+ T L+ + T I
Sbjct: 749 GQEVVVDTSLES--PAGLAIDWVTNKLYWT-----------------------DAGTDRI 783
Query: 12937 FVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKD 13116
V DG ++ +L +P ++ P G + ++D G KIE A MD + RQ+I+
Sbjct: 784 EVANTDGSMRTVLIWENLDRPRDIVVEPMGGYMYWTDWGASPKIERAGMDASGRQVIISS 843
Query: 13117 LVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDR-HIPYAVDVFENHIY 13293
+ P +AID G R+YW D + ++ +DGS+R ++ + P+ + ++ IY
Sbjct: 844 NLTWPNGLAIDYG-SQRLYWADAGMKTIEFAGLDGSKRKVLIGSQLPHPFGLTLYGERIY 902
Query: 13294 WLSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCV 13473
W ++K++ D+ L +LE+ + V + + T E CSHLC+
Sbjct: 903 WTDWQTKSIQSADRLTGLDRETLQENLENLMDIHVFHR-RRPPVSTPCAMENGGCSHLCL 961
Query: 13474 SLPS-TGFACLCPDGIVPQLDG 13536
P+ +GF+C CP GI DG
Sbjct: 962 RSPNPSGFSCTCPTGINLLSDG 983
Score = 99.4 bits (246), Expect = 2e-18
Identities = 55/195 (28%), Positives = 105/195 (53%)
Frame = +1
Query: 12952 DGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSP 13131
DG K +V +L P A++ G + ++D G +AK+E + MDG+ R +++ + + P
Sbjct: 1097 DGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTDWGENAKLERSGMDGSDRAVLINNNLGWP 1156
Query: 13132 TSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSRES 13311
+ +D+ +++ W D R++A +++G+ R T+V PY + + +++IYW ++
Sbjct: 1157 NGLTVDKAS-SQLLWADAHTERIEAADLNGANRHTLVSPVQHPYGLTLLDSYIYWTDWQT 1215
Query: 13312 KTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTG 13491
++++ DK V ++ S+L ++ + A+ G CSHLC+ PS G
Sbjct: 1216 RSIHRADKGTGSNVILVRSNLPGLMDMQAVDR-AQPLGFNKCGSRNGGCSHLCLPRPS-G 1273
Query: 13492 FACLCPDGIVPQLDG 13536
F+C CP GI + DG
Sbjct: 1274 FSCACPTGIQLKGDG 1288
Score = 94.7 bits (234), Expect = 6e-17
Identities = 59/189 (31%), Positives = 83/189 (43%), Gaps = 5/189 (2%)
Frame = +1
Query: 3805 SCTPDQFKCVSSGLCIPASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKCGNGRCILN 3984
+C+P F C +G CI SW SDE R+C D+F C NG CI +
Sbjct: 21 TCSPLDFHC-DNGKCIRRSWVCDGDNDCEDDSDEQD---CPPRECEEDEFPCQNGYCIRS 76
Query: 3985 NWLCDGENDCGDGSDESSERGCKTSMNARKCPFEHVACENDQETCIPLHQLCDGKTHCPG 4164
W CDG+NDCGD SDE + RKC + C + +CI H CDG T C
Sbjct: 77 LWHCDGDNDCGDNSDEQCD--------MRKCSDKEFRCSDG--SCIAEHWYCDGDTDCKD 126
Query: 4165 GTDEGGRCARDLCSADRAGCSFKCHNSPNGPICS-----CPFGEQLVNKTKCEPENECLD 4329
G+DE C ++ P C+ C +G +++ C+ +++C D
Sbjct: 127 GSDEE-----------------NCPSAVPAPPCNLEEFQCAYGRCILDIYHCDGDDDCGD 169
Query: 4330 SSSCSQRCK 4356
S S C+
Sbjct: 170 WSDESDCCE 178
Score = 93.2 bits (230), Expect = 2e-16
Identities = 56/188 (29%), Positives = 96/188 (50%), Gaps = 1/188 (0%)
Frame = +1
Query: 12952 DGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSP 13131
DG K ++ L +P A+ P G + ++D G AKIE A++DG+ R++++ + P
Sbjct: 1401 DGSCRKVLINNSLDEPRAIAVFPRKGYLFWTDWGHIAKIERANLDGSERKVLINTDLGWP 1460
Query: 13132 TSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSRES 13311
+ +D RIYWVD R+++ +++G R +V P+A+ + IYW ++
Sbjct: 1461 NGLTLDYDT-RRIYWVDAHLDRIESADLNGKLRQVLVSHVSHPFALTQQDRWIYWTDWQT 1519
Query: 13312 KTLYVQDKF-GRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPST 13488
K++ DK+ GR + +VLA+ +G + + T G C+HLC + S
Sbjct: 1520 KSIQRVDKYSGRNKETVLAN--VEGLMDIIVVSPQRQTGTNACGVNNGGCTHLCFARAS- 1576
Query: 13489 GFACLCPD 13512
F C CPD
Sbjct: 1577 DFVCACPD 1584
Score = 75.9 bits (185), Expect = 3e-11
Identities = 56/209 (26%), Positives = 82/209 (38%), Gaps = 21/209 (10%)
Frame = +1
Query: 127 SASVNTASSVCNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDTY 306
S + + C +F C+ G CI W +SD+ C +
Sbjct: 180 SGQLGASHQPCRSGEFMCDSGLCINAGWRCDGDADCDD------------QSDERNCKQF 227
Query: 307 TWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGK 486
HS C+ RCD DCAD SDE++C + + + F+C +GR C K C+G
Sbjct: 228 RCHSGRCVRLSWRCDGEDDCADNSDEENCENTGSPQCALDQFLCWNGR-CIGQRKLCNGV 286
Query: 487 YDCRDLSDE-----------KDSCSRNHTACFQ--------YQFRCADKTQCIQKSWVCD 609
DC D SDE +++C+ N+ C Q Q C + + C
Sbjct: 287 NDCGDNSDESPQQNCRPRTGEENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTEDGHTCQ 346
Query: 610 GSKDCADGSDEPDTCEFKKCTANE--FQC 690
+CA E C + CT +E FQC
Sbjct: 347 DVNECA----EEGYCS-QGCTNSEGAFQC 370
Score = 54.3 bits (129), Expect = 9e-05
Identities = 35/101 (34%), Positives = 48/101 (46%), Gaps = 2/101 (1%)
Frame = +1
Query: 3049 SHPNELEAKCACRQGFMINKENNHSCQKDPAEKIEQLCSSNSTQFQCKNGRCIPKEWKCD 3228
SH + C G IN C D A+ +Q N QF+C +GRC+ W+CD
Sbjct: 186 SHQPCRSGEFMCDSGLCINA--GWRCDGD-ADCDDQSDERNCKQFRCHSGRCVRLSWRCD 242
Query: 3229 GENDCLDESDEIDEKGDKCFH--ETECAENTIKCRNTKKCI 3345
GE+DC D SDE + C + +CA + C N +CI
Sbjct: 243 GEDDCADNSDE-----ENCENTGSPQCALDQFLCWN-GRCI 277
Score = 53.5 bits (127), Expect = 1e-04
Identities = 33/100 (33%), Positives = 41/100 (41%), Gaps = 1/100 (1%)
Frame = +1
Query: 10753 PCGDNNGGC-SHLCLIGAGGNGYTCSCPDQFVLLSDQKTCEPNCTERQFACGGDDAKCIP 10929
PC C S LC+ C DQ SD++ C +QF C +C+
Sbjct: 189 PCRSGEFMCDSGLCINAGWRCDGDADCDDQ----SDERNC------KQFRC--HSGRCVR 236
Query: 10930 KLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNC 11049
W CDGE DC D SDE G C + +F C N C
Sbjct: 237 LSWRCDGEDDCADNSDEENCENTGSPQCALDQFLCWNGRC 276
Score = 49.7 bits (117), Expect = 0.002
Identities = 29/106 (27%), Positives = 57/106 (53%), Gaps = 3/106 (2%)
Frame = +1
Query: 12988 LQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNR 13167
++ A+ P G++ +SD+ LH +I A++DG+ + I+ + + +A+D G +
Sbjct: 1023 MKNTIAIGVDPQEGKVYWSDSTLH-RISRANLDGSQHEDIITTGLQTTDGLAVD-AIGRK 1080
Query: 13168 IYWVDPKYRRVDAVNIDGSERTTVV-HDRHIPYAVDVFE--NHIYW 13296
+YW D R++ N+DGS R +V + P A+ ++ +YW
Sbjct: 1081 VYWTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYW 1126
Score = 38.5 bits (88), Expect = 4.9
Identities = 24/93 (25%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
Frame = +1
Query: 13027 GRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDA 13206
G++ Y+D L I AD++G++ + ++ + + +A+D N +YW D ++A
Sbjct: 1340 GKVYYTDVFLDV-IRRADLNGSNMETVIGRGLKTTDGLAVDWVARN-LYWTDTGRNTIEA 1397
Query: 13207 VNIDGSERTTVVHDR-HIPYAVDVF--ENHIYW 13296
+DGS R ++++ P A+ VF + +++W
Sbjct: 1398 SRLDGSCRKVLINNSLDEPRAIAVFPRKGYLFW 1430
>gi|34856544|ref|XP_342465.1| low density lipoprotein receptor-related
protein 4 [Rattus norvegicus]
Length = 1998
Score = 646 bits (1667), Expect = 0.0
Identities = 500/1825 (27%), Positives = 799/1825 (43%), Gaps = 115/1825 (6%)
Frame = +1
Query: 3160 CSSNSTQFQCKNGR-----CIPKEWKCDGENDCLDESDEIDEKGDKCFHETECAENTIKC 3324
C+ + F C CIP +W+CDG+NDC D SDE D C
Sbjct: 81 CACGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDE-----DGC------------- 122
Query: 3325 RNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNHRCIPEQWKXXXX 3504
P C+ F CDN +CI W
Sbjct: 123 ---------------------------------TLPTCSPLDFHCDNGKCIRRSWVCDGD 149
Query: 3505 XXXXXXXXEKLEMCGNATCAANQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQC 3684
E + C C ++F C NG CI W CDGDNDC D +DE +C +C
Sbjct: 150 NDCEDDSDE--QDCPPRECEEDEFPCQNGYCIRSLWHCDGDNDCGDNSDE---QCDMRKC 204
Query: 3685 SALQFRCANGRQCVPLRNHXXXXXXXXXXXXXXX--XAVTAESCTPDQFKCVSSGLCI-- 3852
S +FRC++G C+ + AV + C ++F+C + G CI
Sbjct: 205 SDKEFRCSDG-SCIAEHWYCDGDTDCKDGSDEESCPSAVPSPPCNLEEFQC-AYGRCILD 262
Query: 3853 -----------------PASWKXXXXXXXXXXSDEPKFGCTSGRQCSSDQFKCGNGRCIL 3981
W+ SDE CT+ C+++QF+C +GRC+
Sbjct: 263 IYHCDGDDDCGDWSDESDCCWRCDGDADCDDQSDERN--CTTS-MCTAEQFRCRSGRCVR 319
Query: 3982 NNWLCDGENDCGDGSDESS------------------------ERGCKTSMN-------- 4065
+W CDGE+DC D SDE + E G +S
Sbjct: 320 LSWRCDGEDDCADNSDEENCENTGSQGRESSQLLKFSLSLWPWEEGLLSSQQPLCLLLLC 379
Query: 4066 ----------------------ARKCPFEHVACENDQETCIPLHQLCDGKTHCPGGTDEG 4179
+ +C + C N + CI +LC+G C +DE
Sbjct: 380 GKDWQSLSPPLQPAKPGSDYEGSPQCASDQFLCWNGR--CIGQRKLCNGVNDCGDNSDES 437
Query: 4180 G------RCARDLCSADRAGCSFKCHNSPNGPICSCPFGEQLVNKTK-CEPENECLDSSS 4338
R + C+ + GC+ KC C+C G +L + C+ NEC +
Sbjct: 438 PQQNCRPRTGEENCNVNNGGCAQKCQMIRGAVQCTCHTGYRLTEDGRTCQDVNECAEEGY 497
Query: 4339 CSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRNRIYYSDHKLDNWHT 4518
CSQ C + + F C C+ GYEL D+R+CK + + +NR I +
Sbjct: 498 CSQGCTNSEGAFQCWCEAGYELRPDRRSCKALG--PEPVLLFANRIDIRQVLPHRSEYTL 555
Query: 4519 FGAIVENAIALAWDSLTDRIYWSDIREKKILSANRNGTNATVFIADGLDITEGIALDWVG 4698
+ENAIAL + + ++WSD+ +IL AN NG+N ++ GL+ G+A+DWV
Sbjct: 556 LLNNLENAIALDFHHRRELVFWSDVTLDRILRANLNGSNVEEVVSTGLESPGGLAVDWVH 615
Query: 4699 RNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQNPCIER 4878
LYW DS + IEVANL D R +L+ Q++ +PR IA+ P +G ++WTDWG P IE
Sbjct: 616 DKLYWTDSGTSRIEVANL-DGAHRKVLLWQSLEKPRAIALHPMEGTIYWTDWGNTPRIEA 674
Query: 4879 ASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQVLASSKF 5058
+SMDG+ R+II T ++WPN + +DY R+Y+ D+K I+ N DGS R V+ S+
Sbjct: 675 SSMDGSGRRIIADTHLFWPNGLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVI--SQG 732
Query: 5059 VQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALGVVAVHPVLQPVI 5238
+ HP A+ +FED +Y++D + + K+ G E + + + +HP QP
Sbjct: 733 LPHPFAITVFEDSLYWTDWHTKSINSANKF-TGKNQEIIRNKLHFPMDIHTLHPQRQPAG 791
Query: 5239 KNNPCSTN--PCSHLCLLNNKNTFTCKCPMGEKLDASGKKCIDDAKPFLVIIQKTNVFGI 5412
KN C N C+HLCL + +N +TC CP G + + C FL+ ++ ++ I
Sbjct: 792 KNR-CGDNNGGCTHLCLPSGQN-YTCACPTGFR-KINSHACAQSLDKFLLFARRMDIRRI 848
Query: 5413 EMNSASEKETPVLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYR 5592
++ + ++PL+ + +A +D+ + ++ ++TD+ I R
Sbjct: 849 SFDTEDLSD-----DVIPLADVRSAVALDWDSRDDHVY----------WTDVSTDT-ISR 892
Query: 5593 STVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRTQGKQYRSVILSND 5772
+ +G + + +++ A L DW L + T IE+ T G +I N
Sbjct: 893 AKWDGTGQKVVVDTSLESPA-GLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWEN- 950
Query: 5773 QSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLVIASNDLAELDHIA 5952
GY++W D G A K+ RAG+D SN VI S++L + +A
Sbjct: 951 -----LDRPRDIVVEPMGGYMYWTDWG---ASPKIERAGMDASNRQVIISSNLTWPNGLA 1002
Query: 5953 IDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGDRLFYADSAFDSIE 6132
ID + R+Y+++A I DG R ++ P GL YG R+++ D SI+
Sbjct: 1003 IDYGSQRLYWADAGMKTIEFAGLDGSKRKVLIGSQLPHPFGLTLYGQRIYWTDWQTKSIQ 1062
Query: 6133 VA-TINGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHINNGNCDHICI----PLM 6297
A + G + ++++ENL +I + PC + NG C H+C+ P
Sbjct: 1063 SADRLTGLDRET----LQENLENLMDIHVFHRQRPPVTTPCAVENGGCSHLCLRSPSPSG 1118
Query: 6298 FAQRTCTCANG--YVKDGQTSCKLFDESFVIVATKTKV------------IGYPIDETQS 6435
F +CTC G + DG+T C SF+I A + V + PI+ T
Sbjct: 1119 F---SCTCPTGINLLLDGKT-CSPGMNSFLIFARRIDVRMVSLDIPYFADVVVPINMTMK 1174
Query: 6436 KGVAMEPIGGLSITGVDYDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTI 6615
+A IG + G Y +S ++ AS + S +I + G T
Sbjct: 1175 NTIA---IGVDPLEGKVYWSDSTLHRISRAS----------LDGSQHEDII--TTGLQTT 1219
Query: 6616 KSLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWA 6795
LA+D I +Y+ D IEV LDG+ RK+L+ ++P +I + ++YW
Sbjct: 1220 DGLAVDAIGRKVYWT--DTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYWT 1277
Query: 6796 DQGQKPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGT 6975
D G+ ++RS +DGS R V++++ + P L VD S + W+DA + I G
Sbjct: 1278 DWGENAKLERSGMDGSDRTVLINNNLGWPNGLTVDKTSSQLLWADAHTERIEVADLNGAN 1337
Query: 6976 PELVRSDIASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDV 7155
+ S + G+ L +YWTD + + RA +L V ++L + D+
Sbjct: 1338 RHTLVSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKSTGSNVIL-----VRSNLPGLMDI 1392
Query: 7156 AVFSSNNQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCARGV-LK--GRTCE-EP 7323
QP + C R C+ LC P +C+C G+ LK G+TC+ P
Sbjct: 1393 QAV-DRAQPLGFNKC----GSRNGGCSHLCLPRPSGF--SCACPTGIQLKGDGKTCDPSP 1445
Query: 7324 DTYIMFSDGDKIIDVAIEPDVKASRPLKDPFPEISNLQTFDVDVNLRRVYFVVESPVGVN 7503
+TY++FS I ++++ D + P P ++N+ + D D +VY+ + V ++
Sbjct: 1446 ETYLLFSSRGSIRRISLDTDDHTD--VHVPVPGLNNVISLDYDSVDGKVYY---TDVFLD 1500
Query: 7504 ISWFSMNNAENPRLVFGASKQPHAKEIRHISDMKLDWLTQKIYFT-TGRGG-KVMAIDTA 7677
+ + N N V G ++ + +DW+ + +Y+T TGR + +D +
Sbjct: 1501 VIRRADLNGSNMETVIGHG-------LKTTDGLAVDWVARNLYWTDTGRNTIEASRLDGS 1553
Query: 7678 GEHLSTIASGDWTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSES 7857
+ S D A+A+ P G LFW+D G+ +IER+NL G RKV+++
Sbjct: 1554 CRKVLINNSLDEPRAIAVFPRKGYLFWTDWGHIA-------KIERANLDGSERKVLINAD 1606
Query: 7858 ISLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNRKVIASGY-RAKSLDIWDRWLYMSD 8034
+ P + +D+ ++IYW D + IE AD +G+ R+V+ S +L DRW+Y +D
Sbjct: 1607 LGWPNGLTLDYDTRRIYWVDAHLDRIESADLNGKLRQVLVSHVSHPFALTQQDRWIYWTD 1666
Query: 8035 PLSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESDVRTRNQVCNALTSQLCKTDNGG 8214
+ + R+DK SG E V+++ + G + + +T C +NGG
Sbjct: 1667 WQTKSIQRVDKYSGRNKETVLAN--VEGLMDIIVVSPQRQTGTNACG--------VNNGG 1716
Query: 8215 CDQLCTVVADDIGLAASKVQCSCND 8289
C LC A D C+C D
Sbjct: 1717 CSHLCFARASDF-------VCACPD 1734
Score = 435 bits (1118), Expect = e-119
Identities = 265/834 (31%), Positives = 379/834 (44%), Gaps = 82/834 (9%)
Frame = +1
Query: 8587 SDELDCPSAVACAEGTFPCSNGH-----CINQTKVCDGHNDCHDEQVSDESLATCPGLPI 8751
+ L+C AC F C+ CI CDG NDC D SDE T P
Sbjct: 76 ASNLEC----ACGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDH--SDEDGCTLP---- 125
Query: 8752 DCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCIPET 8931
C + C N CI+ + +CDG +DC D +DE C ++C + C +G CI
Sbjct: 126 TCSPLDFHCDNGK-CIRRSWVCDGDNDCEDDSDEQD--CPPRECEEDEFPCQNGYCIRSL 182
Query: 8932 WQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFIXXXXXXXXXXXX 9111
W CDGDNDC D DE QCD
Sbjct: 183 WHCDGDNDCGDNSDE--------------------QCDM--------------------- 201
Query: 9112 XHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEK 9291
R C+D+EF C+ + CI W CDGD C G DE +
Sbjct: 202 ---------RKCSDKEFRCSDGS--------CIAEHWYCDGDTDCKDGSDEESCPSAVPS 244
Query: 9292 KECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDE------------------HANCTYSS 9417
CN EF+C+ CI + CDGD+DC D SDE NCT S
Sbjct: 245 PPCNLEEFQCAYGRCILDIYHCDGDDDCGDWSDESDCCWRCDGDADCDDQSDERNCTTSM 304
Query: 9418 CQPDFFQCANHKCVPNSWKCDGNDDCEDGSDEKDCPKNSASAQKASK------------- 9558
C + F+C + +CV SW+CDG DDC D SDE++C + +++S+
Sbjct: 305 CTAEQFRCRSGRCVRLSWRCDGEDDCADNSDEENCENTGSQGRESSQLLKFSLSLWPWEE 364
Query: 9559 ----------------------------------------CSNGQFQCTSGECIDDAKVC 9618
C++ QF C +G CI K+C
Sbjct: 365 GLLSSQQPLCLLLLCGKDWQSLSPPLQPAKPGSDYEGSPQCASDQFLCWNGRCIGQRKLC 424
Query: 9619 DRNFDCTDRSDESSLCFI------DECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISD 9780
+ DC D SDES + C++ C QKC ++ +C C G+ + D
Sbjct: 425 NGVNDCGDNSDESPQQNCRPRTGEENCNVNNGG-CAQKCQMIRGAVQCTCHTGYRLT-ED 482
Query: 9781 QKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLAN 9960
++C +VNEC E CSQ C + G+++C C GY+L D SCK + PEP L AN
Sbjct: 483 GRTCQDVNECAEE-GYCSQGCTNSEGAFQCWCEAGYELRPDRRSCKA--LGPEPVLLFAN 539
Query: 9961 KHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSS 10140
+ IR++ ++Y L +N ++LD + + D R+LR +L+ S+
Sbjct: 540 RIDIRQVLPHRSEYTLLLNNLENAIALDFHHRRELVFWSDVTLDRILRANLNG-----SN 594
Query: 10141 YETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVV 10320
E V+ + G+AVDWV KLY + I V LDG K L+ +++P+AI +
Sbjct: 595 VEEVVSTGLESPGGLAVDWVHDKLYWTDSGTSRIEVANLDGAHRKVLLWQSLEKPRAIAL 654
Query: 10321 HPGKGYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGD 10500
HP +G +++T+W P I ++DGS +A+ L WPN + IDY R++W D
Sbjct: 655 HPMEGTIYWTDWGNTPRIEASSMDGSGRRI-----IADTHLFWPNGLTIDYAGRRMYWVD 709
Query: 10501 AHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETI 10680
A + I + DG+ R+ + +Q H ++ VF+D LYW DW+ + + +K+TGKN+ I
Sbjct: 710 AKHHVIERANLDGSHRKAVISQGLPHPFAITVFEDSLYWTDWHTKSINSANKFTGKNQEI 769
Query: 10681 LKKTVQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQF 10842
++ + P D+ +HP RQPA N CGDNNGGC+HLCL G YTC+CP F
Sbjct: 770 IRNKLHFPMDIHTLHPQRQPAGKNRCGDNNGGCTHLCL--PSGQNYTCACPTGF 821
Score = 418 bits (1074), Expect = e-114
Identities = 318/1083 (29%), Positives = 470/1083 (43%), Gaps = 104/1083 (9%)
Frame = +1
Query: 157 CNENDFRCNDGKCIRTEWXXXXXXXXXXXXXXXXXPHPGCKSDQWQCDT-----YTWH-- 315
C+ DF C++GKCIR W P C+ D++ C WH
Sbjct: 127 CSPLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPCQNGYCIRSLWHCD 186
Query: 316 --------------------------SVSCIAEYQRCDNITDCADGSDEKDCPASTVD-- 411
SCIAE+ CD TDC DGSDE+ CP++
Sbjct: 187 GDNDCGDNSDEQCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEESCPSAVPSPP 246
Query: 412 CSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDSC--------------SRNHTA-- 543
C+ + F CA GR D+ CDG DC D SDE D C RN T
Sbjct: 247 CNLEE-FQCAYGRCILDIYH-CDGDDDCGDWSDESDCCWRCDGDADCDDQSDERNCTTSM 304
Query: 544 CFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANE-------------- 681
C QFRC +C++ SW CDG DCAD SDE + CE E
Sbjct: 305 CTAEQFRCRSG-RCVRLSWRCDGEDDCADNSDE-ENCENTGSQGRESSQLLKFSLSLWPW 362
Query: 682 --------------------FQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKW 801
+Q + QP K DY SD+ C W
Sbjct: 363 EEGLLSSQQPLCLLLLCGKDWQSLSPPLQPAKPGSDYEGSPQCASDQFLC---------W 413
Query: 802 NCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLG----------CQAGCHPSPHG 951
N G CI Q KLC+G DC D +DE QN P G C C
Sbjct: 414 N----GRCIGQRKLCNGVNDCGDNSDESP-QQNCRPRTGEENCNVNNGGCAQKCQMIRGA 468
Query: 952 GECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCANHRPGFTCSCLGDCFTLQMEHGPG 1131
+CTC +GY+L + RTC D+NECAE GYC Q C N F C C G
Sbjct: 469 VQCTCHTGYRLTED-GRTCQDVNECAEEGYCSQGCTNSEGAFQCWCEA-----------G 516
Query: 1132 KDNLTMRGYCVSNNADKMKLFVARREGLYRLNPKNPDEEVKKLASGEFIYGIDFDYGDRK 1311
+ R C + + + LF A R + ++ P E L + E +DF +
Sbjct: 517 YELRPDRRSCKALGPEPVLLF-ANRIDIRQVLPHR-SEYTLLLNNLENAIALDFHHRREL 574
Query: 1312 IFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDV 1491
+FW+D A+++ S ++++ L P LAVDW+ + LY +SG+ RI+V
Sbjct: 575 VFWSDVTLDRILRANLNG----SNVEEVVSTGLESPGGLAVDWVHDKLYWTDSGTSRIEV 630
Query: 1492 SSYDGERRTVLLADGLTLPLDIALDPLRGEMFFT---NQLKLEAAAMDGTNRRTLVNTHT 1662
++ DG R VLL L P IAL P+ G +++T N ++EA++MDG+ RR + +TH
Sbjct: 631 ANLDGAHRKVLLWQSLEKPRAIALHPMEGTIYWTDWGNTPRIEASSMDGSGRRIIADTHL 690
Query: 1663 HQVSGIVVDITAKRVYWVDPKVDRLESIDYQGNDRR-IVAQGMNVVPHPFGLALFDQYLY 1839
+G+ +D +R+YWVD K +E + G+ R+ +++QG+ PHPF + +F+ LY
Sbjct: 691 FWPNGLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVISQGL---PHPFAITVFEDSLY 747
Query: 1840 WTDWTRLGVIQVEKFGSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPC 2019
WTDW + KF + + N + FPM I HP QP G++ C
Sbjct: 748 WTDWHTKSINSANKFTGKNQEIIRNKLH--FPMDIHTLHPQRQPA-GKNRC-------GD 797
Query: 2020 TNADCEGMCILSKDNGGFGVGYKCACPIGQKLVNGKRCIDSID-YLLFSSNKIVRGIFPE 2196
N C +C+ S G Y CACP G + +N C S+D +LLF+ +R I
Sbjct: 798 NNGGCTHLCLPS------GQNYTCACPTGFRKINSHACAQSLDKFLLFARRMDIRRI--S 849
Query: 2197 INEKALAEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVL 2376
+ + L++ V+P++ + ++ D + ++ D+ +TI R + DG G V+
Sbjct: 850 FDTEDLSDDVIPLADVRSA-----VALDWDSRDDHVYWTDVSTDTISRAKWDGTGQKVVV 904
Query: 2377 VTHNDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITELRD-PVS 2553
T + ++ DW++ +LY+ D + +EV + D +R LI E D P
Sbjct: 905 DTSLESPAGLAIDWVTNKLYWTDAGTDRIEV--------ANTDGSMRTVLIWENLDRPRD 956
Query: 2554 VVVHPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTL 2733
+VV P G +++ + I R +D N QVI ++ L P+ +AID+ RL W D
Sbjct: 957 IVVEPMGGYMYWTDWGASPKIERAGMDASNRQVIISSNLTWPNGLAIDYGSQRLYWADAG 1016
Query: 2734 LKTISCMDFDG-KNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVR 2910
+KTI DG K V + P P +T+ + IY+ + SI+ + G + ++
Sbjct: 1017 MKTIEFAGLDGSKRKVLIGSQLPHPFGLTLYGQRIYWTDWQTKSIQSADRLTGLDRETLQ 1076
Query: 2911 EFGADERSIFSLKACSHQNQPIPDDSREHPCRASQ--CTQLCFATPSESHPNELEAKCAC 3084
E + ++ + Q P+ PC C+ LC +PS S C C
Sbjct: 1077 E---NLENLMDIHVFHRQRPPVTT-----PCAVENGGCSHLCLRSPSPS-----GFSCTC 1123
Query: 3085 RQG 3093
G
Sbjct: 1124 PTG 1126
Score = 387 bits (993), Expect = e-105
Identities = 273/1015 (26%), Positives = 481/1015 (46%), Gaps = 8/1015 (0%)
Frame = +1
Query: 4312 ENECLDSSS-CSQRCKDEKHGFTCSCDEGYELDVDKRTCKVADNVKDTRIYVSNRN--RI 4482
+N C D++ C+ C +TC+C G+ ++ C A ++ ++ + RI
Sbjct: 792 KNRCGDNNGGCTHLCLPSGQNYTCACPTGFR-KINSHAC--AQSLDKFLLFARRMDIRRI 848
Query: 4483 YYSDHKLDNWHTFGAIVENAIALAWDSLTDRIYWSDIREKKILSANRNGTNATVFIADGL 4662
+ L + A V +A+AL WDS D +YW+D+ I A +GT V + L
Sbjct: 849 SFDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDGTGQKVVVDTSL 908
Query: 4663 DITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMF 4842
+ G+A+DWV LYW D+ + IEVAN D RT+L+ +N+ +PR I V+P G M+
Sbjct: 909 ESPAGLAIDWVTNKLYWTDAGTDRIEVANT-DGSMRTVLIWENLDRPRDIVVEPMGGYMY 967
Query: 4843 WTDWGQNPCIERASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDG 5022
WTDWG +P IERA MD ++RQ+I+ + + WPN +A+DY + R+Y+AD+ + I+F DG
Sbjct: 968 WTDWGASPKIERAGMDASNRQVIISSNLTWPNGLAIDYGSQRLYWADAGMKTIEFAGLDG 1027
Query: 5023 SGRTQVLASSKFVQHPHALAIFEDMMYYSDRRLQKLQVYPKYPNGTTSEYPSHTFSKALG 5202
S R ++ S + HP L ++ +Y++D + + +Q + G E +
Sbjct: 1028 SKRKVLIGSQ--LPHPFGLTLYGQRIYWTDWQTKSIQSADRL-TGLDRETLQENLENLMD 1084
Query: 5203 VVAVHPVLQPVIKNNPCSTNPCSHLCLLN-NKNTFTCKCPMGEKLDASGKKCIDDAKPFL 5379
+ H PV CSHLCL + + + F+C CP G L GK C FL
Sbjct: 1085 IHVFHRQRPPVTTPCAVENGGCSHLCLRSPSPSGFSCTCPTGINLLLDGKTCSPGMNSFL 1144
Query: 5380 VIIQKTNVFGIEMNSASEKETPVLAG-MVPLS-GLGNAFDAAYDALSEEMFILEHTNHAK 5553
+ ++ +V + + + P A +VP++ + N D L +++ + T H
Sbjct: 1145 IFARRIDVRMVSL------DIPYFADVVVPINMTMKNTIAIGVDPLEGKVYWSDSTLH-- 1196
Query: 5554 TLAQITTDSAIYRSTVNGGNKTKMFSSAVPDDAYCLGFDWNGRNLVVGNKITQTIEIIRT 5733
+++ + D + + + G +T L D GR + + T IE+
Sbjct: 1197 RISRASLDGSQHEDIITTGLQT----------TDGLAVDAIGRKVYWTDTGTNRIEVGNL 1246
Query: 5734 QGKQYRSVILSNDQSXXXXXXXXXXXXXXXKGYVFWLDRGGGAADAKVARAGLDGSNPLV 5913
G + ++ N S G+++W D G +AK+ R+G+DGS+ V
Sbjct: 1247 DGSMRKVLVWQNLDS------PRAIVLYHEMGFMYWTDWG---ENAKLERSGMDGSDRTV 1297
Query: 5914 IASNDLAELDHIAIDTTNTRVYFSEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFYGD 6093
+ +N+L + + +D T++++ +++A RI +G +RH ++S + P GL
Sbjct: 1298 LINNNLGWPNGLTVDKTSSQLLWADAHTERIEVADLNGANRHTLVSP-VQHPYGLTLLDS 1356
Query: 6094 RLFYADSAFDSIEVATINGDSQPPQWTHFKKDVENLANIKALQPRASSSGHPCHINNGNC 6273
+++ D SI A + S + ++ L +I+A+ + C NG C
Sbjct: 1357 YIYWTDWQTRSIHRADKSTGSNV---ILVRSNLPGLMDIQAVDRAQPLGFNKCGSRNGGC 1413
Query: 6274 DHICIPLMFAQRTCTCANG-YVKDGQTSCKLFDESFVIVATKTKVIGYPIDETQSKGVAM 6450
H+C+P + +C C G +K +C E++++ +++ + +D V +
Sbjct: 1414 SHLCLPRP-SGFSCACPTGIQLKGDGKTCDPSPETYLLFSSRGSIRRISLDTDDHTDVHV 1472
Query: 6451 EPIGGL-SITGVDYDYESKTIYVAEASGINKGITAYTIGESSPRAVIRDSIGSLTIKSLA 6627
P+ GL ++ +DYD +Y + I + S+ VI G T LA
Sbjct: 1473 -PVPGLNNVISLDYDSVDGKVYYTDV--FLDVIRRADLNGSNMETVI--GHGLKTTDGLA 1527
Query: 6628 IDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQ 6807
+DW+ N+Y+ D R IE S+LDG+ RK+L+ + P +IAV P YL+W D G
Sbjct: 1528 VDWVARNLYWT--DTGRNTIEASRLDGSCRKVLINNSLDEPRAIAVFPRKGYLFWTDWGH 1585
Query: 6808 KPTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRVRSTGGTPELV 6987
I+R+ LDGS R+V++++ + P L +D ++ IYW DA +D I G +++
Sbjct: 1586 IAKIERANLDGSERKVLINADLGWPNGLTLDYDTRRIYWVDAHLDRIESADLNGKLRQVL 1645
Query: 6988 RSDIASAAGVALHGQNMYWTDNRLEKLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFS 7167
S ++ + + +YWTD + + + R + + TV A+++ + D+ V S
Sbjct: 1646 VSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGR-----NKETVLANVEGLMDIIVVS 1700
Query: 7168 SNNQPRASSPCQITDNLRKSPCTQLCFATPGTQTPTCSCARGVLKGRTCEEPDTY 7332
Q ++ C + + C+ LCFA C+C +EPD++
Sbjct: 1701 PQRQ-TGTNACGVNN----GGCSHLCFAR--ASDFVCACP---------DEPDSH 1739
Score = 314 bits (805), Expect = 4e-83
Identities = 236/810 (29%), Positives = 340/810 (41%), Gaps = 81/810 (10%)
Frame = +1
Query: 11359 ECAQIECKKGWTRCSSSY----RCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCA 11526
ECA C + C+ S CIP C+G +DC D+SDED PTC + +F C
Sbjct: 80 ECA---CGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDEDGCTLPTCSPL-DFHC- 134
Query: 11527 TSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQ 11706
+GKCI R W+CD +NDC D+SDE D R C E EF C +G CI CDG
Sbjct: 135 DNGKCIRRSWVCDGDNDCEDDSDEQDCP----PRECEEDEFPCQNGYCIRSLWHCDGDND 190
Query: 11707 CSDGLDESQCTLRRCLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCED-VSRRTCSP 11883
C D DE QC +R+C +C DG+CIAEH +CD DC + +DE C V C+
Sbjct: 191 CGDNSDE-QCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEESCPSAVPSPPCNL 249
Query: 11884 FEFECANSVCIPRKFMXXXXXXXXXXSDETSSECR---SAQCDPPL-------------R 12015
EF+CA CI + SDE+ R A CD +
Sbjct: 250 EEFQCAYGRCILDIYHCDGDDDCGDWSDESDCCWRCDGDADCDDQSDERNCTTSMCTAEQ 309
Query: 12016 FRCAHSRLCLNILQLCNGFNDCGPNDFSDEH----------------------------- 12108
FRC R C+ + C+G +DC N SDE
Sbjct: 310 FRCRSGR-CVRLSWRCDGEDDCADN--SDEENCENTGSQGRESSQLLKFSLSLWPWEEGL 366
Query: 12109 ---------LSMC-----------------SSFSEYGDCSSDQFKCANGKCVNGTVACDR 12210
L +C S + C+SDQF C NG+C+ C+
Sbjct: 367 LSSQQPLCLLLLCGKDWQSLSPPLQPAKPGSDYEGSPQCASDQFLCWNGRCIGQRKLCNG 426
Query: 12211 KDDCGDASDEI---GCSKHGGKTSCEAFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSP 12381
+DCGD SDE C G+ +C NNGGC C +R C C G+R +
Sbjct: 427 VNDCGDNSDESPQQNCRPRTGEENCNV--NNGGCAQKCQMIRGAVQCTCHTGYRL-TEDG 483
Query: 12382 KECIDIDECAGNNTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIG 12561
+ C D++ECA C+Q C N++G++ C C YE + C+A G ++
Sbjct: 484 RTCQDVNECAEEGYCSQGCTNSEGAFQCWCEAGYELR-----PDRRSCKALGPEPVLLFA 538
Query: 12562 ADDSLVQLSLHGSGTNRHXXXXXXXXXXXXXXXXXXPRKELMYWIDGSERTIYRSAIANG 12741
+ Q+ H R R+EL++W S+ T+ R AN
Sbjct: 539 NRIDIRQVLPH-----RSEYTLLLNNLENAIALDFHHRRELVFW---SDVTLDRILRANL 590
Query: 12742 NQSHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQ 12921
N S+ + + + P +AVD+ L+ +
Sbjct: 591 NGSNVEEVVSTGLES----PGGLAVDWVHDKLYWT-----------------------DS 623
Query: 12922 NTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQ 13101
T I V DG + K ++ L++P A+ P G I ++D G +IE + MDG+ R+
Sbjct: 624 GTSRIEVANLDGAHRKVLLWQSLEKPRAIALHPMEGTIYWTDWGNTPRIEASSMDGSGRR 683
Query: 13102 IIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVV-HDRHIPYAVDVF 13278
II +F P + ID G R+YWVD K+ ++ N+DGS R V+ P+A+ VF
Sbjct: 684 IIADTHLFWPNGLTIDYA-GRRMYWVDAKHHVIERANLDGSHRKAVISQGLPHPFAITVF 742
Query: 13279 ENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQC 13458
E+ +YW +K++ +KF ++ + L + + + G C
Sbjct: 743 EDSLYWTDWHTKSINSANKFTGKNQEIIRNKLHFPMDIHTLHPQRQPAGKNRCGDNNGGC 802
Query: 13459 SHLCVSLPS-TGFACLCPDGIVPQLDGSCA 13545
+HLC LPS + C CP G +CA
Sbjct: 803 THLC--LPSGQNYTCACPTGFRKINSHACA 830
Score = 248 bits (633), Expect = 3e-63
Identities = 198/732 (27%), Positives = 333/732 (45%), Gaps = 12/732 (1%)
Frame = +1
Query: 1018 NECAEF-GYCDQLCANHRPGFTCSCLGDCFTLQMEHGPGKDNLTMRGYCVSNNADKMKLF 1194
N C + G C LC +TC+C G K N + + + DK LF
Sbjct: 793 NRCGDNNGGCTHLCLPSGQNYTCAC---------PTGFRKIN----SHACAQSLDKFLLF 839
Query: 1195 VARREGLYRLNPKNPD--EEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDE 1368
ARR + R++ D ++V LA +D+D D ++WTD + A D
Sbjct: 840 -ARRMDIRRISFDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDGT 898
Query: 1369 GEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLP 1548
G+ K + SL P LA+DW+TN LY ++G+ RI+V++ DG RTVL+ + L P
Sbjct: 899 GQ----KVVVDTSLESPAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRP 954
Query: 1549 LDIALDPLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVD 1719
DI ++P+ G M++T+ K+E A MD +NR+ +++++ +G+ +D ++R+YW D
Sbjct: 955 RDIVVEPMGGYMYWTDWGASPKIERAGMDASNRQVIISSNLTWPNGLAIDYGSQRLYWAD 1014
Query: 1720 PKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKF-GSDT 1896
+ +E G+ R+++ +PHPFGL L+ Q +YWTDW + ++ G D
Sbjct: 1015 AGMKTIEFAGLDGSKRKVLIGSQ--LPHPFGLTLYGQRIYWTDWQTKSIQSADRLTGLDR 1072
Query: 1897 KLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCT--NADCEGMCILSKDNGG 2070
+ L N EN M I +H P + PC N C +C+ S G
Sbjct: 1073 ETLQENLEN---LMDIHVFHRQRPP-----------VTTPCAVENGGCSHLCLRSPSPSG 1118
Query: 2071 FGVGYKCACPIG-QKLVNGKRCIDSID-YLLFSSNKIVRGIFPEINEKALAEAVLPISPI 2244
F C CP G L++GK C ++ +L+F+ VR + +I A+ V+PI+
Sbjct: 1119 F----SCTCPTGINLLLDGKTCSPGMNSFLIFARRIDVRMVSLDI--PYFADVVVPINMT 1172
Query: 2245 SQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVLVTHNDGLFSMSFDWIS 2424
+ I + D +++D + I R DG ++ T ++ D I
Sbjct: 1173 MKNTIA----IGVDPLEGKVYWSDSTLHRISRASLDGSQHEDIITTGLQTTDGLAVDAIG 1228
Query: 2425 KQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITE-LRDPVSVVVHPWKGLLFYAEAM 2601
+++Y+ D N +EV + D +R+ L+ + L P ++V++ G +++ +
Sbjct: 1229 RKVYWTDTGTNRIEVGNL--------DGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTDWG 1280
Query: 2602 RPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKTISCMDFDGKNVVK 2781
A + R +DG + V+ N LG P+ + +D ++L W D + I D +G N
Sbjct: 1281 ENAKLERSGMDGSDRTVLINNNLGWPNGLTVDKTSSQLLWADAHTERIEVADLNGANRHT 1340
Query: 2782 LDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSH 2961
L P +T+++ YIY+ + SI R K G +VR ++ L
Sbjct: 1341 LVSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKSTGSNVILVRS------NLPGLMDIQA 1394
Query: 2962 QNQPIPDDSREHPCRASQCTQLCFATPSESHPNELEAKCACRQGFMINKENNHSCQKDPA 3141
++ P + R C+ LC PS CAC G + K + +C DP+
Sbjct: 1395 VDRAQPLGFNKCGSRNGGCSHLCLPRPS-------GFSCACPTGIQL-KGDGKTC--DPS 1444
Query: 3142 EKIEQLCSSNST 3177
+ L SS +
Sbjct: 1445 PETYLLFSSRGS 1456
Score = 233 bits (593), Expect = 1e-58
Identities = 128/349 (36%), Positives = 186/349 (52%), Gaps = 3/349 (0%)
Frame = +1
Query: 9802 NECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKI 9981
N+C GCS C + + C C G QL D +C + PE + L +++ IR+I
Sbjct: 1404 NKCGSRNGGCSHLCLPRPSGFSCACPTGIQLKGDGKTC---DPSPETYLLFSSRGSIRRI 1460
Query: 9982 SIDGNKY---ELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETV 10152
S+D + + + G +NV+SLD D + K Y D + R DL+ S+ ETV
Sbjct: 1461 SLDTDDHTDVHVPVPGLNNVISLDYDSVDGKVYYTDVFLDVIRRADLNG-----SNMETV 1515
Query: 10153 LRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGK 10332
+ H + T+G+AVDWV R LY + +I LDG K LI + + +P+AI V P K
Sbjct: 1516 IGHGLKTTDGLAVDWVARNLYWTDTGRNTIEASRLDGSCRKVLINNSLDEPRAIAVFPRK 1575
Query: 10333 GYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLN 10512
GYLF+T+W I R LDGS L DLGWPN + +DY + R++W DAHL+
Sbjct: 1576 GYLFWTDWGHIAKIERANLDGSERK-----VLINADLGWPNGLTLDYDTRRIYWVDAHLD 1630
Query: 10513 EIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKT 10692
I D +G R + SH ++ D ++YW DW + + R DK++G+N+ +
Sbjct: 1631 RIESADLNGK-LRQVLVSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVLAN 1689
Query: 10693 VQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQ 10839
V+ D+ +V P RQ N CG NNGGCSHLC A + + C+CPD+
Sbjct: 1690 VEGLMDIIVVSPQRQTG-TNACGVNNGGCSHLCF--ARASDFVCACPDE 1735
Score = 223 bits (569), Expect = 8e-56
Identities = 203/734 (27%), Positives = 325/734 (43%), Gaps = 19/734 (2%)
Frame = +1
Query: 994 FHRTCSDINE-CA-EFGYCDQLCANHRP--GFTCSCLGDCFTLQMEHGPGKDNLTMRGYC 1161
FHR + CA E G C LC GF+C+C P NL + G
Sbjct: 1088 FHRQRPPVTTPCAVENGGCSHLCLRSPSPSGFSCTC------------PTGINLLLDGKT 1135
Query: 1162 VSNNADKMKLFVARREGLYRLN---PKNPDEEVKKLASGEFIYGIDFDYGDRKIFWTDRL 1332
S + +F ARR + ++ P D V + + I D + K++W+D
Sbjct: 1136 CSPGMNSFLIF-ARRIDVRMVSLDIPYFADVVVPINMTMKNTIAIGVDPLEGKVYWSDST 1194
Query: 1333 AHSAFSADVDDEGEISQIKKLSLKSLVYPRCLAVDWITNTLYIIESGSRRIDVSSYDGER 1512
H A +D SQ + + L LAVD I +Y ++G+ RI+V + DG
Sbjct: 1195 LHRISRASLDG----SQHEDIITTGLQTTDGLAVDAIGRKVYWTDTGTNRIEVGNLDGSM 1250
Query: 1513 RTVLLADGLTLPLDIALDPLRGEMFFTN---QLKLEAAAMDGTNRRTLVNTHTHQVSGIV 1683
R VL+ L P I L G M++T+ KLE + MDG++R L+N + +G+
Sbjct: 1251 RKVLVWQNLDSPRAIVLYHEMGFMYWTDWGENAKLERSGMDGSDRTVLINNNLGWPNGLT 1310
Query: 1684 VDITAKRVYWVDPKVDRLESIDYQGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLG 1863
VD T+ ++ W D +R+E D G +R + ++ V HP+GL L D Y+YWTDW
Sbjct: 1311 VDKTSSQLLWADAHTERIEVADLNGANRHTL---VSPVQHPYGLTLLDSYIYWTDWQTRS 1367
Query: 1864 VIQVEKF-GSDTKLLWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEG 2040
+ + +K GS+ L+ SN + + P+ G ++C + N C
Sbjct: 1368 IHRADKSTGSNVILVRSNLPGLMDIQAVDRAQPL-----GFNKCGSR-------NGGCSH 1415
Query: 2041 MCILSKDNGGFGVGYKCACPIGQKLV-NGKRCIDSID-YLLFSSNKIVRGIFPEINEKAL 2214
+C+ G+ CACP G +L +GK C S + YLLFSS +R I + ++
Sbjct: 1416 LCLPRPS------GFSCACPTGIQLKGDGKTCDPSPETYLLFSSRGSIRRISLDTDDHTD 1469
Query: 2215 AEAVLPISPISQRRIGMYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGAAPVL---VTH 2385
+P + ++ D +Y D+ + I R +G V+ +
Sbjct: 1470 VHVPVP-------GLNNVISLDYDSVDGKVYYTDVFLDVIRRADLNGSNMETVIGHGLKT 1522
Query: 2386 NDGLFSMSFDWISKQLYYVDNIRNSLEVVKIGETGLVHPDELVRRQLITE-LRDPVSVVV 2562
DGL + DW+++ LY+ D RN++E ++ D R+ LI L +P ++ V
Sbjct: 1523 TDGL---AVDWVARNLYWTDTGRNTIEASRL--------DGSCRKVLINNSLDEPRAIAV 1571
Query: 2563 HPWKGLLFYAEAMRPAAIYRCHIDGQNCQVIRNTTLGRPSEMAIDFAENRLCWGDTLLKT 2742
P KG LF+ + A I R ++DG +V+ N LG P+ + +D+ R+ W D L
Sbjct: 1572 FPRKGYLFWTDWGHIAKIERANLDGSERKVLINADLGWPNGLTLDYDTRRIYWVDAHLDR 1631
Query: 2743 ISCMDFDGKNVVKLDIDNPIPVAITIMNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGA 2922
I D +GK L P A+T + +IY+ + SI+RV K +G + V A
Sbjct: 1632 IESADLNGKLRQVLVSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVL---A 1688
Query: 2923 DERSIFSLKACSHQNQPIPDDSREHPCRASQ--CTQLCFATPSESHPNELEAKCACRQGF 3096
+ + + S Q Q + + C + C+ LCFA S + CAC
Sbjct: 1689 NVEGLMDIIVVSPQRQ-----TGTNACGVNNGGCSHLCFARAS-------DFVCACP--- 1733
Query: 3097 MINKENNHSCQKDP 3138
++ ++H C P
Sbjct: 1734 --DEPDSHPCSLVP 1745
Score = 195 bits (496), Expect = 2e-47
Identities = 110/361 (30%), Positives = 171/361 (46%), Gaps = 3/361 (0%)
Frame = +1
Query: 9802 NECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKI 9981
N C + GC+ C +Y C C G++ + H+C ++ + F L A + IR+I
Sbjct: 793 NRCGDNNGGCTHLCLPSGQNYTCACPTGFR-KINSHACAQSL---DKFLLFARRMDIRRI 848
Query: 9982 SIDGNKYE---LAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETV 10152
S D + + V+LD D + Y D + R D + + V
Sbjct: 849 SFDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDG-----TGQKVV 903
Query: 10153 LRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGK 10332
+ ++ G+A+DWV KLY + I V DG LI + + +P+ IVV P
Sbjct: 904 VDTSLESPAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRPRDIVVEPMG 963
Query: 10333 GYLFFTEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLN 10512
GY+++T+W P I R +D S + +L WPN +AIDY S RL+W DA +
Sbjct: 964 GYMYWTDWGASPKIERAGMDASNRQV-----IISSNLTWPNGLAIDYGSQRLYWADAGMK 1018
Query: 10513 EIGFMDFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKT 10692
I F DG+ R+ + + H + ++ +YW DW + + D+ TG + L++
Sbjct: 1019 TIEFAGLDGSKRKVLIGSQLPHPFGLTLYGQRIYWTDWQTKSIQSADRLTGLDRETLQEN 1078
Query: 10693 VQLPNDLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTCE 10872
++ D+ + H R P PC NGGCSHLCL +G++C+CP LL D KTC
Sbjct: 1079 LENLMDIHVFHRQRPPV-TTPCAVENGGCSHLCLRSPSPSGFSCTCPTGINLLLDGKTCS 1137
Query: 10873 P 10875
P
Sbjct: 1138 P 1138
Score = 191 bits (486), Expect = 3e-46
Identities = 112/357 (31%), Positives = 169/357 (46%), Gaps = 6/357 (1%)
Frame = +1
Query: 9826 GCSQKC--DDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPEPFFLLANKHYIRKISIDGNK 9999
GCS C + C C G L D +C F + A + +R +S+D
Sbjct: 1105 GCSHLCLRSPSPSGFSCTCPTGINLLLDGKTCSPGM---NSFLIFARRIDVRMVSLDIPY 1161
Query: 10000 YELAAQGFD----NVVSLDIDLTEKKAYLIDQGKLRLLRVDLDEMDSPLSSYETVLRHNV 10167
+ + N +++ +D E K Y D R+ R LD S +E ++ +
Sbjct: 1162 FADVVVPINMTMKNTIAIGVDPLEGKVYWSDSTLHRISRASLDG-----SQHEDIITTGL 1216
Query: 10168 YGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQPKAIVVHPGKGYLFF 10347
T+G+AVD +GRK+Y + I V LDG K L+ + P+AIV++ G++++
Sbjct: 1217 QTTDGLAVDAIGRKVYWTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYW 1276
Query: 10348 TEWSLQPYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFM 10527
T+W + R +DGS L ++LGWPN + +D S +L W DAH I
Sbjct: 1277 TDWGENAKLERSGMDGSDRT-----VLINNNLGWPNGLTVDKTSSQLLWADAHTERIEVA 1331
Query: 10528 DFDGNGRRHIPAQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPN 10707
D +G RH H + + D Y+YW DW R + R DK TG N +++ +
Sbjct: 1332 DLNG-ANRHTLVSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKSTGSNVILVRSNLPGLM 1390
Query: 10708 DLRIVHPMRQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTCEPN 10878
D++ V QP N CG NGGCSHLCL +G++C+CP L D KTC+P+
Sbjct: 1391 DIQAV-DRAQPLGFNKCGSRNGGCSHLCL--PRPSGFSCACPTGIQLKGDGKTCDPS 1444
Score = 144 bits (364), Expect = 5e-32
Identities = 115/416 (27%), Positives = 166/416 (39%), Gaps = 51/416 (12%)
Frame = +1
Query: 8383 PYNFQCGDGSCILLGATCDSKPDCADASDENPNYCNTRSCPEDYNLCTNRRCIDSAKKCN 8562
P +F C +G CI CD DC D SDE C R C ED C N CI S C+
Sbjct: 129 PLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQD--CPPRECEEDEFPCQNGYCIRSLWHCD 186
Query: 8563 HIDDCGDGSDELDCPSAVACAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPG 8742
+DCGD SDE C C++ F CS+G CI + CDG DC D + + P
Sbjct: 187 GDNDCGDNSDE-QCDMR-KCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEESCPSAVPS 244
Query: 8743 LPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADE-----------------NQLFCM 8871
P C + +C CI CDG DDCGD +DE ++ C
Sbjct: 245 PP--CNLEEFQCAYGR-CILDIYHCDGDDDCGDWSDESDCCWRCDGDADCDDQSDERNCT 301
Query: 8872 NQQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGK------KICVGDYL 9033
C RC SGRC+ +W+CDG++DC+D DE + T + G+ K + +
Sbjct: 302 TSMCTAEQFRCRSGRCVRLSWRCDGEDDCADNSDEENCENTGSQGRESSQLLKFSLSLWP 361
Query: 9034 FQ---CDNLKCISRAFIXXXXXXXXXXXXXHSRHGC---GNRTCTDQEFHCTSNAKLAQP 9195
++ + + + + ++ G G+ C +F C +
Sbjct: 362 WEEGLLSSQQPLCLLLLCGKDWQSLSPPLQPAKPGSDYEGSPQCASDQFLCWNG------ 415
Query: 9196 KYECIPRAWLCDGDVTCAGGEDESTEL-C--KTEKKECNKGEFRCSN---------QHCI 9339
CI + LC+G C DES + C +T ++ CN C+ Q
Sbjct: 416 --RCIGQRKLCNGVNDCGDNSDESPQQNCRPRTGEENCNVNNGGCAQKCQMIRGAVQCTC 473
Query: 9340 HSTWE-------CDGDNDCLDGSDEHANCTYSSCQPDFFQC---ANHKCVPNSWKC 9477
H+ + C N+C + CT S FQC A ++ P+ C
Sbjct: 474 HTGYRLTEDGRTCQDVNECAEEGYCSQGCTNSE---GAFQCWCEAGYELRPDRRSC 526
Score = 134 bits (336), Expect = 8e-29
Identities = 82/243 (33%), Positives = 113/243 (45%), Gaps = 24/243 (9%)
Frame = +1
Query: 274 CKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGRQ 453
C + C +CI +CD DC D SDE C T CS + F C +G+
Sbjct: 83 CGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDEDGCTLPT--CSPLD-FHCDNGK- 138
Query: 454 CFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADG 633
C S CDG DC D SDE+D R C + +F C + CI+ W CDG DC D
Sbjct: 139 CIRRSWVCDGDNDCEDDSDEQDCPPRE---CEEDEFPCQNG-YCIRSLWHCDGDNDCGDN 194
Query: 634 SDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDEC-----------GEY 780
SDE C+ +KC+ EF+C + C + CD DC D SDE+ C E+
Sbjct: 195 SDEQ--CDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEESCPSAVPSPPCNLEEF 252
Query: 781 RCPPGK-----WNCPGTGHC------IDQLKLCDGSKDCADGADEQQCSQNLCPS--LGC 921
+C G+ ++C G C D CDG DC D +DE+ C+ ++C + C
Sbjct: 253 QCAYGRCILDIYHCDGDDDCGDWSDESDCCWRCDGDADCDDQSDERNCTTSMCTAEQFRC 312
Query: 922 QAG 930
++G
Sbjct: 313 RSG 315
Score = 120 bits (301), Expect = 1e-24
Identities = 107/383 (27%), Positives = 145/383 (36%), Gaps = 51/383 (13%)
Frame = +1
Query: 10879 CTERQFACGGD---DAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNC 11049
C F C + CIP W CDG+ DC D SDE G C C +F C N C
Sbjct: 83 CGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDEDG---CTLPTCSPLDFHCDNGKC 139
Query: 11050 TRPFQIXXXXXXXXXXXXEQNCD-KACDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEA 11226
R + EQ+C + C+ F C G CI + SDE
Sbjct: 140 IRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPCQ-NGYCIRSLWHCDGDNDCGDNSDEQ 198
Query: 11227 DTLCMSAERNCTAEEFRCNNNKCIAKAWRXXXXXXXXXXXXE--------TPEC--AQIE 11376
+ R C+ +EFRC++ CIA+ W E +P C + +
Sbjct: 199 CDM-----RKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEESCPSAVPSPPCNLEEFQ 253
Query: 11377 CKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDK--QRCP---TCDDVGE--------- 11514
C G RCI + C+G DDC D SDE RC CDD +
Sbjct: 254 CAYG--------RCILDIYHCDGDDDCGDWSDESDCCWRCDGDADCDDQSDERNCTTSMC 305
Query: 11515 ----FRCATSGKCIPRRWMCDTENDCGDNSDELDA-SCGGTTRPCSE------SEFRCND 11661
FRC SG+C+ W CD E+DC DNSDE + + G R S+ S + +
Sbjct: 306 TAEQFRCR-SGRCVRLSWRCDGEDDCADNSDEENCENTGSQGRESSQLLKFSLSLWPWEE 364
Query: 11662 GKCIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQ------------CDDGTCIAEHKW 11805
G +C + C L+ PG C +G CI + K
Sbjct: 365 GLLSSQQPLC-LLLLCGKDWQSLSPPLQPAKPGSDYEGSPQCASDQFLCWNGRCIGQRKL 423
Query: 11806 CDRKKDCPNAADELHCEDVSRRT 11874
C+ DC + +DE ++ RT
Sbjct: 424 CNGVNDCGDNSDESPQQNCRPRT 446
Score = 116 bits (290), Expect = 2e-23
Identities = 112/425 (26%), Positives = 155/425 (36%), Gaps = 62/425 (14%)
Frame = +1
Query: 10765 NNGGCSHLCLIGAGGNGYTCSCPDQFVLLSDQKTCEPN-CTERQFACGGDDAKCIPKLWY 10941
+NG C + G N C D SD++ C P C E +F C + CI LW+
Sbjct: 135 DNGKCIRRSWVCDGDN----DCEDD----SDEQDCPPRECEEDEFPC--QNGYCIRSLWH 184
Query: 10942 CDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRPFQIXXXXXXXXXXXXEQNCDK 11121
CDG+ DC D SDE C R C EF+C++ +C E++C
Sbjct: 185 CDGDNDCGDNSDEQ----CDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEESCPS 240
Query: 11122 A-----CDPWMFKCAATGRCIPRRFTXXXXXXXXXRSDEADTLC----------MSAERN 11256
A C+ F+CA GRCI + SDE+D S ERN
Sbjct: 241 AVPSPPCNLEEFQCAY-GRCILDIYHCDGDDDCGDWSDESDCCWRCDGDADCDDQSDERN 299
Query: 11257 CT-----AEEFRCNNNKCIAKAWRXXXXXXXXXXXXET---------------------- 11355
CT AE+FRC + +C+ +WR E
Sbjct: 300 CTTSMCTAEQFRCRSGRCVRLSWRCDGEDDCADNSDEENCENTGSQGRESSQLLKFSLSL 359
Query: 11356 ------------PECAQIECKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTC 11499
P C + C K W S + + G C +
Sbjct: 360 WPWEEGLLSSQQPLCLLLLCGKDWQSLSPPLQPAKPGSDYEGSPQCASD----------- 408
Query: 11500 DDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRP-CSESEFRCNDGKCIP 11676
+F C +G+CI +R +C+ NDCGDNSDE S RP E N+G C
Sbjct: 409 ----QFLC-WNGRCIGQRKLCNGVNDCGDNSDE---SPQQNCRPRTGEENCNVNNGGCAQ 460
Query: 11677 GSKVCDGTIQCSDGLDESQCTLRRCLPGHRQCDDG-TC-----IAEHKWCDRKKDCPNAA 11838
++ G +QC+ C G+R +DG TC AE +C + C N+
Sbjct: 461 KCQMIRGAVQCT------------CHTGYRLTEDGRTCQDVNECAEEGYC--SQGCTNSE 506
Query: 11839 DELHC 11853
C
Sbjct: 507 GAFQC 511
Score = 111 bits (277), Expect = 6e-22
Identities = 80/290 (27%), Positives = 131/290 (44%), Gaps = 2/290 (0%)
Frame = +1
Query: 12673 RKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAV 12852
R + +YW D S TI R+ GQK+ VD + P +A+D+ T L+
Sbjct: 876 RDDHVYWTDVSTDTISRA-----KWDGTGQKVVVDTSLES--PAGLAIDWVTNKLYWT-- 926
Query: 12853 SENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGR 13032
+ T I V DG ++ +L +P ++ P G
Sbjct: 927 ---------------------DAGTDRIEVANTDGSMRTVLIWENLDRPRDIVVEPMGGY 965
Query: 13033 ICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDAVN 13212
+ ++D G KIE A MD ++RQ+I+ + P +AID G R+YW D + ++
Sbjct: 966 MYWTDWGASPKIERAGMDASNRQVIISSNLTWPNGLAIDYG-SQRLYWADAGMKTIEFAG 1024
Query: 13213 IDGSERTTVVHDR-HIPYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHT 13389
+DGS+R ++ + P+ + ++ IYW ++K++ D+ L +LE+
Sbjct: 1025 LDGSKRKVLIGSQLPHPFGLTLYGQRIYWTDWQTKSIQSADRLTGLDRETLQENLENLMD 1084
Query: 13390 VRVSQKYAKDTQRTVSGCERAQCSHLCVSLPS-TGFACLCPDGIVPQLDG 13536
+ V + + T E CSHLC+ PS +GF+C CP GI LDG
Sbjct: 1085 IHVFHR-QRPPVTTPCAVENGGCSHLCLRSPSPSGFSCTCPTGINLLLDG 1133
Score = 102 bits (255), Expect = 2e-19
Identities = 56/157 (35%), Positives = 72/157 (45%), Gaps = 5/157 (3%)
Frame = +1
Query: 520 SCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNK 699
+C R+H C + CI W CDG DC D SDE D C C+ +F C N
Sbjct: 82 ACGRSHFTC---AVSALGECTCIPAQWQCDGDNDCGDHSDE-DGCTLPTCSPLDFHCDNG 137
Query: 700 RCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGAD 879
+C R + CD +DC D+SDE +C C ++ C G+CI L CDG DC D +D
Sbjct: 138 KCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPCQ-NGYCIRSLWHCDGDNDCGDNSD 196
Query: 880 EQQCSQNLC--PSLGCQAGCHPSPH---GGECTCPSG 975
E QC C C G + H G+ C G
Sbjct: 197 E-QCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDG 232
Score = 98.6 bits (244), Expect = 4e-18
Identities = 54/195 (27%), Positives = 104/195 (52%)
Frame = +1
Query: 12952 DGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSP 13131
DG K +V +L P A++ G + ++D G +AK+E + MDG+ R +++ + + P
Sbjct: 1247 DGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTDWGENAKLERSGMDGSDRTVLINNNLGWP 1306
Query: 13132 TSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSRES 13311
+ +D+ +++ W D R++ +++G+ R T+V PY + + +++IYW ++
Sbjct: 1307 NGLTVDK-TSSQLLWADAHTERIEVADLNGANRHTLVSPVQHPYGLTLLDSYIYWTDWQT 1365
Query: 13312 KTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTG 13491
++++ DK V ++ S+L ++ + A+ G CSHLC+ PS G
Sbjct: 1366 RSIHRADKSTGSNVILVRSNLPGLMDIQAVDR-AQPLGFNKCGSRNGGCSHLCLPRPS-G 1423
Query: 13492 FACLCPDGIVPQLDG 13536
F+C CP GI + DG
Sbjct: 1424 FSCACPTGIQLKGDG 1438
Score = 94.0 bits (232), Expect = 1e-16
Identities = 57/188 (30%), Positives = 96/188 (50%), Gaps = 1/188 (0%)
Frame = +1
Query: 12952 DGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSP 13131
DG K ++ L +P A+ P G + ++D G AKIE A++DG+ R++++ + P
Sbjct: 1551 DGSCRKVLINNSLDEPRAIAVFPRKGYLFWTDWGHIAKIERANLDGSERKVLINADLGWP 1610
Query: 13132 TSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDVFENHIYWLSRES 13311
+ +D RIYWVD R+++ +++G R +V P+A+ + IYW ++
Sbjct: 1611 NGLTLDYDT-RRIYWVDAHLDRIESADLNGKLRQVLVSHVSHPFALTQQDRWIYWTDWQT 1669
Query: 13312 KTLYVQDKF-GRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPST 13488
K++ DK+ GR + +VLA+ +G + + T G CSHLC + S
Sbjct: 1670 KSIQRVDKYSGRNKETVLAN--VEGLMDIIVVSPQRQTGTNACGVNNGGCSHLCFARAS- 1726
Query: 13489 GFACLCPD 13512
F C CPD
Sbjct: 1727 DFVCACPD 1734
Score = 70.9 bits (172), Expect = 9e-10
Identities = 53/184 (28%), Positives = 74/184 (39%), Gaps = 1/184 (0%)
Frame = +1
Query: 3127 QKDPAEKIEQLCSSNSTQFQCKNGRCIPKEWKCDGENDCLDESDEIDEKGDKCFHETECA 3306
Q D +C++ QF+C++GRC+ W+CDGE+DC D SDE
Sbjct: 294 QSDERNCTTSMCTAE--QFRCRSGRCVRLSWRCDGEDDCADNSDE--------------- 336
Query: 3307 ENTIKCRNTKKCIPAQXXXXXXXXXXXXXXXXVKYCKDGQKPVCAAKKFQCDNHRCIPEQ 3486
EN C NT + Q+P+C C +
Sbjct: 337 EN---CENTGS---QGRESSQLLKFSLSLWPWEEGLLSSQQPLCLL--LLCG------KD 382
Query: 3487 WKXXXXXXXXXXXXEKLEMCGNATCAANQFSCANGRCIPIYWLCDGDNDCYDGTDED-KE 3663
W+ E G+ CA++QF C NGRCI LC+G NDC D +DE ++
Sbjct: 383 WQSLSPPLQPAKPGSDYE--GSPQCASDQFLCWNGRCIGQRKLCNGVNDCGDNSDESPQQ 440
Query: 3664 RCPP 3675
C P
Sbjct: 441 NCRP 444
Score = 48.5 bits (114), Expect = 0.005
Identities = 29/106 (27%), Positives = 56/106 (52%), Gaps = 3/106 (2%)
Frame = +1
Query: 12988 LQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNR 13167
++ A+ P G++ +SD+ LH +I A +DG+ + I+ + + +A+D G +
Sbjct: 1173 MKNTIAIGVDPLEGKVYWSDSTLH-RISRASLDGSQHEDIITTGLQTTDGLAVD-AIGRK 1230
Query: 13168 IYWVDPKYRRVDAVNIDGSERTTVV-HDRHIPYAVDVFE--NHIYW 13296
+YW D R++ N+DGS R +V + P A+ ++ +YW
Sbjct: 1231 VYWTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYW 1276
Score = 45.8 bits (107), Expect = 0.030
Identities = 37/136 (27%), Positives = 55/136 (40%), Gaps = 26/136 (19%)
Frame = +1
Query: 8314 GKDY-----PTQCVLRGSNSEPAKECLPPYNFQCGDGSCILLGATCDSKPDCADASDENP 8478
GKD+ P Q GS+ E + +C F C +G CI C+ DC D SDE+P
Sbjct: 380 GKDWQSLSPPLQPAKPGSDYEGSPQCASD-QFLCWNGRCIGQRKLCNGVNDCGDNSDESP 438
Query: 8479 NY-CNTRSCPEDYNL----C----------------TNRRCIDSAKKCNHIDDCGDGSDE 8595
C R+ E+ N+ C T R + + C +++C ++E
Sbjct: 439 QQNCRPRTGEENCNVNNGGCAQKCQMIRGAVQCTCHTGYRLTEDGRTCQDVNEC---AEE 495
Query: 8596 LDCPSAVACAEGTFPC 8643
C +EG F C
Sbjct: 496 GYCSQGCTNSEGAFQC 511
Score = 38.9 bits (89), Expect = 3.7
Identities = 24/93 (25%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
Frame = +1
Query: 13027 GRICYSDAGLHAKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDPKYRRVDA 13206
G++ Y+D L I AD++G++ + ++ + + +A+D N +YW D ++A
Sbjct: 1490 GKVYYTDVFLDV-IRRADLNGSNMETVIGHGLKTTDGLAVDWVARN-LYWTDTGRNTIEA 1547
Query: 13207 VNIDGSERTTVVHDR-HIPYAVDVF--ENHIYW 13296
+DGS R ++++ P A+ VF + +++W
Sbjct: 1548 SRLDGSCRKVLINNSLDEPRAIAVFPRKGYLFW 1580