Homology by BLASTX
BLASTX 2.2.4 [Aug-26-2002]
Query= F52B10_1
(5892 letters)
Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
1,967,186 sequences; 661,712,633 total letters
Score E
Sequences producing significant alignments: (bits) Value
gi|25150354|ref|NP_508504.2| non-muscle myosin (nmy-1) [Caenorha... 3495 0.0
gi|7441404|pir||T16416 hypothetical protein F52B10.1 - Caenorhab... 3473 0.0
gi|39591036|emb|CAE58816.1| Hypothetical protein CBG02025 [Caeno... 3310 0.0
gi|31198813|ref|XP_308354.1| ENSANGP00000024069 [Anopheles gambi... 1868 0.0
gi|31198815|ref|XP_308355.1| ENSANGP00000009410 [Anopheles gambi... 1866 0.0
gi|24762816|ref|NP_523860.2| CG15792-PA [Drosophila melanogaster... 1860 0.0
gi|24762818|ref|NP_726506.1| CG15792-PB [Drosophila melanogaster... 1860 0.0
gi|1141790|gb|AAB09051.1| nonmuscle myosin-II heavy chain [Droso... 1844 0.0
gi|1572480|gb|AAB09048.1| nonmuscle myosin-II heavy chain [Droso... 1844 0.0
gi|547969|sp|Q99323|MYSN_DROME Myosin heavy chain, non-muscle (Z... 1836 0.0
gi|157953|gb|AAA28713.1| non-muscle myosin heavy chain 1836 0.0
gi|1572482|gb|AAB09050.1| nonmuscle myosin-II heavy chain [Droso... 1835 0.0
gi|1572481|gb|AAB09049.1| nonmuscle myosin-II heavy chain [Droso... 1835 0.0
gi|2119295|pir||S61477 myosin II heavy chain, non-muscle - fruit... 1833 0.0
gi|212450|gb|AAA48986.1| nonmuscle myosin heavy chain 1824 0.0
gi|212449|gb|AAA48985.1| nonmuscle myosin heavy chain 1821 0.0
gi|33598964|ref|NP_780469.1| myosin heavy chain 10, non-muscle; ... 1820 0.0
gi|41406064|ref|NP_005955.1| myosin, heavy polypeptide 10, non-m... 1819 0.0
gi|1346640|sp|P35580|MYHA_HUMAN Myosin heavy chain, nonmuscle ty... 1817 0.0
gi|45382679|ref|NP_990805.1| nonmuscle myosin heavy chain [Gallu... 1816 0.0
gi|27807325|ref|NP_777259.1| myosin, heavy polypeptide 10, non-m... 1816 0.0
gi|212451|gb|AAA48987.1| nonmuscle myosin heavy chain 1812 0.0
gi|13928704|ref|NP_113708.1| myosin heavy chain 10, non-muscle; ... 1812 0.0
gi|422615|pir||A47297 myosin heavy chain form B, nonmuscle - Afr... 1790 0.0
gi|45382693|ref|NP_990808.1| myosin heavy chain, nonmuscle [Gall... 1785 0.0
gi|45384060|ref|NP_990605.1| MHC mRNA [Gallus gallus] >gnl|BL_OR... 1779 0.0
gi|3915778|sp|P10587|MYHB_CHICK Myosin heavy chain, gizzard smoo... 1777 0.0
gi|11276949|pir||A59282 nonmuscle myosin II heavy chain A - Afri... 1776 0.0
gi|20137006|ref|NP_071855.1| myosin heavy chain IX [Mus musculus... 1774 0.0
gi|27529744|dbj|BAA74889.2| KIAA0866 protein [Homo sapiens] 1769 0.0
gi|13124875|ref|NP_074035.1| smooth muscle myosin heavy chain 11... 1769 0.0
gi|12667788|ref|NP_002464.1| myosin, heavy polypeptide 9, non-mu... 1769 0.0
gi|13124879|ref|NP_002465.1| smooth muscle myosin heavy chain 11... 1769 0.0
gi|1346644|sp|P35748|MYHB_RABIT Myosin heavy chain, smooth muscl... 1759 0.0
gi|50510675|dbj|BAD32323.1| mKIAA0866 protein [Mus musculus] 1758 0.0
gi|109322|pir||A41604 myosin heavy chain, smooth muscle, long sp... 1757 0.0
gi|20070691|gb|AAH26142.1| Myh11 protein [Mus musculus] 1757 0.0
gi|625305|pir||A61231 myosin heavy chain nonmuscle form A - human 1755 0.0
gi|6981236|ref|NP_037326.1| myosin, heavy polypeptide 9; Myosin,... 1751 0.0
gi|7305295|ref|NP_038635.1| myosin heavy chain 11, smooth muscle... 1744 0.0
gi|13431676|sp|O08638|MYHB_MOUSE Myosin heavy chain, smooth musc... 1744 0.0
gi|19879404|gb|AAK85118.1| non-muscle myosin II heavy chain [Lol... 1739 0.0
gi|111999|pir||S21801 myosin heavy chain, neuronal [similarity] ... 1691 0.0
gi|14530418|emb|CAA99841.2| Hypothetical protein F20G4.3 [Caenor... 1649 0.0
gi|7499530|pir||T21174 hypothetical protein F20G4.3 - Caenorhabd... 1649 0.0
gi|25150089|ref|NP_492186.2| non-muscle myosin, cytoplasmic, hea... 1649 0.0
gi|1477559|gb|AAC47238.1| non-muscle myosin heavy chain II 1649 0.0
gi|2104553|gb|AAC31665.1| Myosin heavy chain (MHY11) (5'partial)... 1646 0.0
gi|28972888|dbj|BAC65860.1| mKIAA3005 protein [Mus musculus] 1642 0.0
gi|47214961|emb|CAG10783.1| unnamed protein product [Tetraodon n... 1633 0.0
gi|29336026|ref|NP_082297.1| nonmuscle myosin heavy chain [Mus m... 1630 0.0
gi|33638127|gb|AAQ24173.1| nonmuscle myosin II-C heavy chain [Mu... 1630 0.0
gi|33563340|ref|NP_079005.2| myosin, heavy polypeptide 14; nonmu... 1624 0.0
gi|39582082|emb|CAE63725.1| Hypothetical protein CBG08250 [Caeno... 1598 0.0
gi|34868040|ref|XP_239866.2| similar to myosin [Rattus norvegicus] 1576 0.0
gi|47223930|emb|CAG06107.1| unnamed protein product [Tetraodon n... 1570 0.0
gi|47221621|emb|CAF97886.1| unnamed protein product [Tetraodon n... 1508 0.0
gi|34856033|ref|XP_218617.2| similar to nonmuscle myosin heavy c... 1493 0.0
gi|29436380|gb|AAH49849.1| MYH9 protein [Homo sapiens] 1389 0.0
gi|49117916|gb|AAH72844.1| Unknown (protein for IMAGE:4971062) [... 1374 0.0
gi|553596|gb|AAA59888.1| cellular myosin heavy chain 1371 0.0
gi|47211645|emb|CAF92169.1| unnamed protein product [Tetraodon n... 1354 0.0
gi|28703810|gb|AAH47253.1| LOC398083 protein [Xenopus laevis] 1342 0.0
gi|9229910|dbj|BAB00612.1| myosin [Mizuhopecten yessoensis] 1256 0.0
gi|13786876|pdb|1I84|S Chain S, Cryo-Em Structure Of The Heavy M... 1255 0.0
gi|26337053|dbj|BAC32210.1| unnamed protein product [Mus musculus] 1207 0.0
gi|3986194|dbj|BAA34954.1| myosin heavy chain [Dugesia japonica] 1203 0.0
gi|28277520|gb|AAH45324.1| Wu:fi22c04 protein [Danio rerio] 1203 0.0
gi|11276951|pir||A59287 myosin heavy chain - fluke (Schistosoma ... 1197 0.0
gi|127773|sp|P24733|MYS_AEQIR Myosin heavy chain, striated muscl... 1191 0.0
gi|33468583|emb|CAE30366.1| SI:dZ204D19.2 (novel protein similar... 1188 0.0
gi|497653|gb|AAC46490.1| myosin heavy chain >gnl|BL_ORD_ID|76853... 1182 0.0
gi|5817598|gb|AAD52842.1| myosin heavy chain [Pecten maximus] 1179 0.0
gi|45383005|ref|NP_989918.1| myosin heavy chain [Gallus gallus] ... 1179 0.0
gi|38014765|gb|AAH60471.1| LOC398083 protein [Xenopus laevis] 1178 0.0
gi|6708502|gb|AAD09454.2| superfast myosin heavy chain [Felis ca... 1173 0.0
gi|34785893|gb|AAH57729.1| LOC398719 protein [Xenopus laevis] 1172 0.0
gi|1408194|gb|AAB03661.1| myosin heavy chain [Placopecten magell... 1171 0.0
gi|1408192|gb|AAB03660.1| myosin heavy chain [Placopecten magell... 1170 0.0
gi|47217964|emb|CAG02247.1| unnamed protein product [Tetraodon n... 1170 0.0
gi|26337045|dbj|BAC32206.1| unnamed protein product [Mus musculus] 1168 0.0
gi|45382109|ref|NP_990097.1| myosin heavy chain [Gallus gallus] ... 1164 0.0
gi|20891813|ref|XP_147228.1| myosin heavy chain 11, smooth muscl... 1163 0.0
gi|18859641|ref|NP_542766.1| myosin, heavy polypeptide 7, cardia... 1155 0.0
gi|4557773|ref|NP_000248.1| myosin, heavy polypeptide 7, cardiac... 1154 0.0
gi|12053672|emb|CAC20413.1| beta-myosin heavy chain [Homo sapiens] 1153 0.0
gi|12060489|dbj|BAB20630.1| myosin heavy chain slow isoform [Sus... 1153 0.0
gi|41386711|ref|NP_777152.1| myosin, heavy polypeptide 7, cardia... 1152 0.0
gi|21907902|dbj|BAC05681.1| myosin heavy chain slow [Equus cabal... 1151 0.0
gi|8393807|ref|NP_058936.1| myosin heavy chain, polypeptide 7; m... 1147 0.0
gi|11276954|pir||A59234 slow myosin heavy chain 3 - quail >gnl|B... 1145 0.0
gi|31235848|ref|XP_319310.1| ENSANGP00000024621 [Anopheles gambi... 1145 0.0
gi|3041708|sp|P13540|MYH7_MESAU Myosin heavy chain, cardiac musc... 1145 0.0
gi|38177589|gb|AAF00096.2| ventricular myosin heavy chain [Danio... 1145 0.0
gi|6093461|sp|P79293|MYH7_PIG Myosin heavy chain, cardiac muscle... 1143 0.0
gi|31235836|ref|XP_319308.1| ENSANGP00000012555 [Anopheles gambi... 1142 0.0
gi|50757621|ref|XP_415581.1| PREDICTED: similar to fast myosin h... 1140 0.0
gi|13537551|dbj|BAB40711.1| myosin [Mizuhopecten yessoensis] 1140 0.0
gi|31235852|ref|XP_319311.1| ENSANGP00000022605 [Anopheles gambi... 1139 0.0
gi|31235842|ref|XP_319309.1| ENSANGP00000024129 [Anopheles gambi... 1139 0.0
gi|8393804|ref|NP_058935.1| myosin heavy chain, polypeptide 6; m... 1139 0.0
gi|29727|emb|CAA37068.1| cardiac beta myosin heavy chain [Homo s... 1139 0.0
gi|476355|pir||A46762 myosin alpha heavy chain, cardiac muscle -... 1138 0.0
gi|6754774|ref|NP_034986.1| myosin, heavy polypeptide 6, cardiac... 1136 0.0
gi|49523259|gb|AAH75407.1| Unknown (protein for MGC:89159) [Xeno... 1136 0.0
gi|27529913|dbj|BAA96036.2| KIAA1512 protein [Homo sapiens] 1135 0.0
gi|3041706|sp|P13533|MYH6_HUMAN Myosin heavy chain, cardiac musc... 1135 0.0
gi|31235859|ref|XP_319312.1| ENSANGP00000025304 [Anopheles gambi... 1135 0.0
gi|42662294|ref|XP_371398.2| myosin, heavy polypeptide 7B, cardi... 1135 0.0
gi|191618|gb|AAA37159.1| alpha cardiac myosin heavy chain 1135 0.0
gi|27764861|ref|NP_002462.1| myosin heavy chain 6; myosin heavy ... 1134 0.0
gi|3252880|gb|AAC24207.1| myosin heavy chain isoform A [Loligo p... 1134 0.0
gi|50838836|ref|NP_001001302.1| chick atrial myosin heavy chain ... 1134 0.0
gi|38091410|ref|XP_354614.1| myosin, heavy polypeptide 3, skelet... 1133 0.0
gi|6981234|ref|NP_036736.1| myosin, heavy polypeptide 3; Myosin,... 1131 0.0
gi|191622|gb|AAA37161.1| alpha cardiac myosin heavy chain 1130 0.0
gi|24584706|ref|NP_724006.1| CG17927-PI [Drosophila melanogaster... 1130 0.0
gi|50368680|gb|AAH76678.1| Unknown (protein for MGC:79657) [Xeno... 1130 0.0
gi|3043372|sp|P11055|MYH3_HUMAN Myosin heavy chain, fast skeleta... 1128 0.0
gi|9800488|gb|AAF99315.1| fast myosin heavy chain isoform 3 [Gal... 1127 0.0
gi|11342672|ref|NP_002461.1| myosin, heavy polypeptide 3, skelet... 1127 0.0
gi|86355|pir||JX0178 myosin heavy chain, fast skeletal muscle, a... 1127 0.0
gi|21907898|dbj|BAC05679.1| myosin heavy chain 2a [Equus caballus] 1126 0.0
gi|50797117|ref|XP_423922.1| PREDICTED: chick atrial myosin heav... 1126 0.0
gi|1842051|gb|AAB47555.1| myosin heavy chain [Gallus gallus] 1125 0.0
gi|5360750|dbj|BAA82146.1| myosin heavy chain 2x [Sus scrofa] 1125 0.0
gi|13432175|sp|P13538|MYSS_CHICK Myosin heavy chain, skeletal mu... 1125 0.0
gi|24584702|ref|NP_724004.1| CG17927-PD [Drosophila melanogaster... 1125 0.0
gi|28574239|ref|NP_523587.4| CG17927-PH [Drosophila melanogaster... 1125 0.0
gi|47575800|ref|NP_001001244.1| myosin heavy chain [Xenopus trop... 1125 0.0
gi|22121649|gb|AAM88909.1| fast myosin heavy chain HCII [Gallus ... 1125 0.0
gi|24584700|ref|NP_724003.1| CG17927-PF [Drosophila melanogaster... 1124 0.0
gi|5360746|dbj|BAA82144.1| myosin heavy chain 2a [Sus scrofa] 1123 0.0
gi|5360748|dbj|BAA82145.1| myosin heavy chain 2b [Sus scrofa] 1123 0.0
gi|41386691|ref|NP_776542.1| myosin, heavy polypeptide 1, skelet... 1122 0.0
gi|3915779|sp|P13539|MYH6_MESAU Myosin heavy chain, cardiac musc... 1122 0.0
gi|45383668|ref|NP_989559.1| myosin, heavy polypeptide 2, skelet... 1121 0.0
gi|23379831|gb|AAM88910.1| fast myosin heavy chain HCIII [Gallus... 1120 0.0
gi|24584704|ref|NP_724005.1| CG17927-PA [Drosophila melanogaster... 1120 0.0
gi|11321579|ref|NP_003793.1| myosin, heavy polypeptide 13, skele... 1120 0.0
gi|24584712|ref|NP_724008.1| CG17927-PK [Drosophila melanogaster... 1120 0.0
gi|34870880|ref|XP_340818.1| myosin, heavy polypeptide 4 [Rattus... 1119 0.0
gi|24584692|ref|NP_723999.1| CG17927-PC [Drosophila melanogaster... 1119 0.0
gi|24584696|ref|NP_724001.1| CG17927-PE [Drosophila melanogaster... 1119 0.0
gi|157892|gb|AAA28687.1| myosin heavy chain 1118 0.0
gi|50757617|ref|XP_415579.1| PREDICTED: similar to skeletal myos... 1118 0.0
gi|21907900|dbj|BAC05680.1| myosin heavy chain 2x [Equus caballus] 1117 0.0
gi|38091413|ref|XP_354615.1| myosin, heavy polypeptide 1, skelet... 1116 0.0
gi|34870884|ref|XP_213345.2| similar to Myosin heavy chain, skel... 1115 0.0
gi|24584714|ref|NP_724009.1| CG17927-PL [Drosophila melanogaster... 1114 0.0
gi|12003423|gb|AAG43570.1| skeletal muscle myosin heavy chain My... 1114 0.0
gi|7669506|ref|NP_005954.2| myosin, heavy polypeptide 1, skeleta... 1114 0.0
gi|13431716|sp|Q9UKX2|MYH2_HUMAN Myosin heavy chain, skeletal mu... 1114 0.0
gi|24584694|ref|NP_724000.1| CG17927-PG [Drosophila melanogaster... 1114 0.0
gi|24584716|ref|NP_724010.1| CG17927-PM [Drosophila melanogaster... 1113 0.0
gi|13560269|dbj|BAB40920.1| myosin heavy chain 2a [Bos taurus] 1113 0.0
gi|24584710|ref|NP_724007.1| CG17927-PB [Drosophila melanogaster... 1113 0.0
gi|37360930|dbj|BAC98374.1| KIAA2034 protein [Homo sapiens] 1113 0.0
gi|11024712|ref|NP_060003.1| myosin, heavy polypeptide 4, skelet... 1112 0.0
gi|42476190|ref|NP_060004.2| myosin, heavy polypeptide 2, skelet... 1112 0.0
gi|157891|gb|AAA28686.1| myosin heavy chain 1112 0.0
gi|38347761|dbj|BAD01606.1| myosin heavy chain [Lethenteron japo... 1110 0.0
gi|20455497|sp|P05661|MYSA_DROME Myosin heavy chain, muscle 1110 0.0
gi|13431707|sp|Q28641|MYH4_RABIT Myosin heavy chain, skeletal mu... 1110 0.0
gi|1346637|sp|P02565|MYH3_CHICK Myosin heavy chain, fast skeleta... 1109 0.0
gi|6683485|dbj|BAA89233.1| skeletal myosin heavy chain [Gallus g... 1108 0.0
gi|17561652|ref|NP_505094.1| myosin heavy chain family member (5... 1108 0.0
gi|11276955|pir||A59236 embryonic muscle myosin heavy chain - se... 1108 0.0
gi|24584698|ref|NP_724002.1| CG17927-PJ [Drosophila melanogaster... 1108 0.0
gi|3041707|sp|P13535|MYH8_HUMAN Myosin heavy chain, skeletal mus... 1107 0.0
gi|2119300|pir||I38055 myosin heavy chain, perinatal skeletal mu... 1107 0.0
gi|86358|pir||A29320 myosin heavy chain, fast skeletal muscle, e... 1107 0.0
gi|15384839|emb|CAC59753.1| myosin heavy chain [Paracirrhites fo... 1105 0.0
gi|13431711|sp|Q90339|MYSS_CYPCA Myosin heavy chain, fast skelet... 1104 0.0
gi|4505301|ref|NP_002463.1| myosin, heavy polypeptide 8, skeleta... 1103 0.0
gi|50512294|ref|NP_694514.2| myosin, heavy polypeptide 2, fast m... 1102 0.0
gi|11121496|emb|CAC14945.1| dJ756N5.1.1 (Continues in Em:AL13332... 1102 0.0
gi|39584408|emb|CAE72546.1| Hypothetical protein CBG19730 [Caeno... 1097 0.0
gi|39592202|emb|CAE75423.1| Hypothetical protein CBG23416 [Caeno... 1096 0.0
gi|47208995|emb|CAF91401.1| unnamed protein product [Tetraodon n... 1096 0.0
gi|7209643|dbj|BAA92289.1| myosin heavy chain [Seriola dumerili] 1095 0.0
gi|32566139|ref|NP_506065.2| MYOsin heavy chain structural gene,... 1095 0.0
gi|9971579|dbj|BAB12571.1| myosin heavy chain [Pennahia argentata] 1094 0.0
gi|38488753|ref|NP_942118.1| myosin, heavy polypeptide 6, cardia... 1092 0.0
gi|48103366|ref|XP_395558.1| similar to CG15792-PA [Apis mellifera] 1092 0.0
gi|39645256|gb|AAH18933.2| MYH14 protein [Homo sapiens] 1091 0.0
gi|17509401|ref|NP_493596.1| UNCoordinated locomotion UNC-54, en... 1090 0.0
gi|2351219|dbj|BAA22067.1| myosin heavy chain [Cyprinus carpio] 1088 0.0
gi|127743|sp|P02566|MYSB_CAEEL Myosin heavy chain B (MHC B) >gnl... 1088 0.0
gi|2351221|dbj|BAA22068.1| myosin heavy chain [Cyprinus carpio] 1086 0.0
gi|345377|pir||A45627 myosin heavy chain [similarity] - nematode... 1082 0.0
gi|41350446|gb|AAS00505.1| fast skeletal muscle myosin heavy cha... 1082 0.0
gi|39590394|emb|CAE66133.1| Hypothetical protein CBG11357 [Caeno... 1082 0.0
gi|11384448|pir||S02771 myosin heavy chain A [similarity] - Caen... 1082 0.0
gi|11276953|pir||A59294 skeletal myosin - nematode (Onchocerca v... 1082 0.0
gi|12657354|emb|CAC27778.1| myosin heavy chain [Notothenia corii... 1079 0.0
gi|30268331|emb|CAD89954.1| hypothetical protein [Homo sapiens] 1078 0.0
gi|47211780|emb|CAF94090.1| unnamed protein product [Tetraodon n... 1078 0.0
gi|34870892|ref|XP_340820.1| similar to Myosin heavy chain, skel... 1068 0.0
gi|34870888|ref|XP_340819.1| similar to myosin heavy chain 2b [R... 1068 0.0
gi|3660083|pdb|1BR1|A Chain A, Smooth Muscle Myosin Motor Domain... 1065 0.0
gi|12657350|emb|CAC27776.1| myosin heavy chain [Notothenia corii... 1064 0.0
gi|21623523|dbj|BAC00871.1| myosin heavy chain [Oncorhynchus keta] 1061 0.0
gi|47213344|emb|CAF92967.1| unnamed protein product [Tetraodon n... 1061 0.0
gi|34859107|ref|XP_230774.2| similar to KIAA1512 protein [Rattus... 1060 0.0
gi|26342663|dbj|BAC34988.1| unnamed protein product [Mus musculus] 1056 0.0
gi|50757613|ref|XP_415578.1| PREDICTED: similar to myosin heavy ... 1047 0.0
gi|3660091|pdb|1BR2|A Chain A, Smooth Muscle Myosin Motor Domain... 1040 0.0
gi|39582764|emb|CAE74227.1| Hypothetical protein CBG21911 [Caeno... 1019 0.0
gi|17508449|ref|NP_492053.1| MYOsin heavy chain structural gene,... 1016 0.0
gi|27529750|dbj|BAA76844.2| KIAA1000 protein [Homo sapiens] 1013 0.0
gi|127751|sp|P02567|MYSD_CAEEL Myosin heavy chain D (MHC D) >gnl... 1013 0.0
gi|39588011|emb|CAE57242.1| Hypothetical protein CBG00120 [Caeno... 1012 0.0
gi|42656791|ref|XP_036988.9| KIAA1000 protein [Homo sapiens] 1011 0.0
gi|25150292|ref|NP_510092.2| MYOsin heavy chain structural gene ... 1009 0.0
gi|127750|sp|P12845|MYSC_CAEEL Myosin heavy chain C (MHC C) >gnl... 1006 0.0
gi|21489941|ref|NP_659210.1| myosin, heavy polypeptide 2, skelet... 1004 0.0
gi|11384452|pir||S05697 myosin heavy chain C [similarity] - Caen... 1004 0.0
gi|28422303|gb|AAH46881.1| Zgc:66156 protein [Danio rerio] 989 0.0
gi|50757921|ref|XP_425359.1| PREDICTED: similar to Myosin heavy ... 986 0.0
gi|3986196|dbj|BAA34955.1| myosin heavy chain [Dugesia japonica] 973 0.0
gi|12697534|emb|CAC28360.1| myosin heavy chain [Toxocara canis] 971 0.0
gi|50757923|ref|XP_425360.1| PREDICTED: similar to fast myosin h... 963 0.0
gi|47847498|dbj|BAD21421.1| mFLJ00279 protein [Mus musculus] 961 0.0
gi|47206494|emb|CAF92339.1| unnamed protein product [Tetraodon n... 949 0.0
gi|31235868|ref|XP_319313.1| ENSANGP00000023782 [Anopheles gambi... 948 0.0
gi|189030|gb|AAA61765.1| nonmuscle myosin heavy chain-A 946 0.0
gi|127774|sp|P08799|MYS2_DICDI Myosin II heavy chain, non muscle... 944 0.0
gi|50757619|ref|XP_415580.1| PREDICTED: similar to myosin, heavy... 942 0.0
gi|42658064|ref|XP_376656.1| hypothetical protein FLJ22037 [Homo... 941 0.0
gi|42658517|ref|XP_379895.1| similar to superfast myosin heavy c... 939 0.0
gi|2119296|pir||I64833 smooth muscle myosin heavy chain isoform ... 936 0.0
gi|2119289|pir||I51893 smooth muscle myosin heavy chain isoform ... 935 0.0
gi|13272546|gb|AAK17202.1| major plasmodial myosin heavy chain [... 931 0.0
gi|38079956|ref|XP_356900.1| similar to KIAA1000 protein [Mus mu... 929 0.0
gi|6682319|emb|CAB64662.1| myosin heavy chain [Mytilus galloprov... 923 0.0
gi|32408499|ref|XP_324731.1| hypothetical protein [Neurospora cr... 915 0.0
gi|50555922|ref|XP_505369.1| hypothetical protein [Yarrowia lipo... 902 0.0
gi|34869316|ref|XP_221489.2| similar to myosin heavy chain [Ratt... 901 0.0
gi|49073352|ref|XP_400901.1| hypothetical protein UM03286.1 [Ust... 900 0.0
gi|6682321|emb|CAB64663.1| pedal retractor muscle myosin heavy c... 892 0.0
gi|49094764|ref|XP_408843.1| hypothetical protein AN4706.2 [Aspe... 887 0.0
gi|46128683|ref|XP_388895.1| hypothetical protein FG08719.1 [Gib... 887 0.0
gi|38100724|gb|EAA47817.1| hypothetical protein MG03060.4 [Magna... 880 0.0
gi|47205442|emb|CAG05719.1| unnamed protein product [Tetraodon n... 851 0.0
gi|3668187|dbj|BAA33452.1| myosin heavy chain [Theragra chalcogr... 848 0.0
gi|47220279|emb|CAG03313.1| unnamed protein product [Tetraodon n... 848 0.0
gi|27469623|gb|AAH41716.1| MYH4 protein [Xenopus laevis] 846 0.0
gi|47227314|emb|CAF96863.1| unnamed protein product [Tetraodon n... 845 0.0
gi|31235874|ref|XP_319314.1| ENSANGP00000022367 [Anopheles gambi... 843 0.0
gi|236788|gb|AAB19994.1| myosin heavy chain=head region [Aequipe... 843 0.0
gi|50259260|gb|EAL21933.1| hypothetical protein CNBC0730 [Crypto... 840 0.0
gi|40889447|pdb|1QVI|A Chain A, Crystal Structure Of Scallop Myo... 840 0.0
gi|24987474|pdb|1KK7|A Chain A, Scallop Myosin In The Near Rigor... 839 0.0
gi|34870895|ref|XP_340821.1| myosin heavy polypeptide 13 [Rattus... 837 0.0
gi|11514304|pdb|1DFL|A Chain A, Scallop Myosin S1 Complexed With... 836 0.0
gi|5107466|pdb|1B7T|A Chain A, Myosin Digested By Papain >gnl|BL... 836 0.0
gi|11514300|pdb|1DFK|A Chain A, Nucleotide-Free Scallop Myosin S... 836 0.0
gi|47940239|gb|AAH72094.1| LOC432141 protein [Xenopus laevis] 827 0.0
gi|18700652|gb|AAL78671.1| myosin heavy chain A [Schmidtea medit... 827 0.0
gi|189036|gb|AAA36349.1| nonmuscle myosin heavy chain (NMHC) 815 0.0
gi|39586574|emb|CAE73701.1| Hypothetical protein CBG21212 [Caeno... 814 0.0
gi|17553462|ref|NP_499769.1| myosin heavy family member (3O511) ... 810 0.0
gi|38173965|gb|AAH61145.1| Myh6 protein [Mus musculus] 806 0.0
gi|4928755|gb|AAD33718.1| myosin heavy chain [Amoeba proteus] 804 0.0
gi|86362|pir||S06117 myosin heavy chain, nonmuscle (clone lambda... 803 0.0
gi|7494129|pir||T18296 myosin heavy chain - Entamoeba histolytic... 799 0.0
gi|28278650|gb|AAH44194.1| Wu:fi38g05 protein [Danio rerio] 797 0.0
gi|627322|pir||JX0317 myosin S-1 heavy chain, cardiac muscle - c... 795 0.0
gi|32766513|gb|AAH54974.1| Unknown (protein for IMAGE:6881110) [... 793 0.0
gi|47205359|emb|CAF96150.1| unnamed protein product [Tetraodon n... 787 0.0
gi|8927455|gb|AAF82093.1| type tonic myosin heavy chain [Rana pi... 780 0.0
gi|47938732|gb|AAH72099.1| LOC432231 protein [Xenopus laevis] 771 0.0
gi|1763304|gb|AAC49908.1| myosin II [Schizosaccharomyces pombe] 768 0.0
gi|19075614|ref|NP_588114.1| myosin ii [Schizosaccharomyces pomb... 768 0.0
gi|38081072|ref|XP_359049.1| similar to myosin heavy chain [Mus ... 767 0.0
gi|19074177|ref|NP_584783.1| MYOSIN HEAVY CHAIN [Encephalitozoon... 767 0.0
gi|26334227|dbj|BAC30831.1| unnamed protein product [Mus musculus] 766 0.0
gi|6321812|ref|NP_011888.1| Myo1 is a type II myosin, is localiz... 765 0.0
gi|127758|sp|P05659|MYSN_ACACA Myosin II heavy chain, non muscle... 760 0.0
gi|19114728|ref|NP_593816.1| myosin-3 isoform, heavy chain (Type... 752 0.0
gi|2731818|gb|AAC04615.1| myosin-II; Myp2p [Schizosaccharomyces ... 752 0.0
gi|8927451|gb|AAF82091.1| type 2 myosin heavy chain [Rana pipiens] 752 0.0
gi|42556325|gb|AAS19751.1| myosin heavy chain [Gasterosteus acul... 751 0.0
gi|8927453|gb|AAF82092.1| type 3 myosin heavy chain [Rana pipiens] 749 0.0
gi|50423117|ref|XP_460139.1| unnamed protein product [Debaryomyc... 749 0.0
gi|46432411|gb|EAK91894.1| hypothetical protein CaO19.13673 [Can... 744 0.0
gi|50308935|ref|XP_454473.1| unnamed protein product [Kluyveromy... 739 0.0
gi|8927449|gb|AAF82090.1| type 1 myosin heavy chain [Rana pipiens] 738 0.0
gi|45185754|ref|NP_983470.1| ACR068Wp [Eremothecium gossypii] >g... 728 0.0
gi|50290619|ref|XP_447742.1| unnamed protein product [Candida gl... 726 0.0
gi|47229711|emb|CAG06907.1| unnamed protein product [Tetraodon n... 705 0.0
gi|7503487|pir||T22234 hypothetical protein F45G2.2 - Caenorhabd... 695 0.0
gi|24158979|pdb|1M8Q|A Chain A, Molecular Models Of Averaged Rig... 693 0.0
gi|1942538|pdb|2MYS|A Chain A, Myosin Subfragment-1, Alpha Carbo... 693 0.0
gi|16974839|pdb|1JWY|A Chain A, Crystal Structure Of The Dynamin... 685 0.0
gi|1827756|pdb|1MNE| Truncated Head Of Myosin From Dictyosteliu... 684 0.0
gi|6980633|pdb|1D0X|A Chain A, Dictyostelium Myosin S1dc (Motor ... 683 0.0
gi|13096618|pdb|1G8X|A Chain A, Structure Of A Genetically Engin... 682 0.0
gi|11513531|pdb|1FMV|A Chain A, Crystal Structure Of The Apo Mot... 682 0.0
gi|2781257|pdb|1MMA| X-Ray Structures Of The Mgadp, Mgatpgammas... 681 0.0
gi|2781087|pdb|1MMN| X-Ray Structures Of The Mgadp, Mgatpgammas... 676 0.0
gi|2914352|pdb|1LVK| X-Ray Crystal Structure Of The Mg (Dot) 2'... 674 0.0
gi|2781258|pdb|1MMG| X-Ray Structures Of The Mgadp, Mgatpgammas... 673 0.0
gi|31235881|ref|XP_319315.1| ENSANGP00000024583 [Anopheles gambi... 673 0.0
gi|5801822|gb|AAD51477.1| beta myosin heavy chain [Felis catus] 659 0.0
gi|47229714|emb|CAG06910.1| unnamed protein product [Tetraodon n... 642 0.0
gi|2144825|pir||MWRBCB myosin beta heavy chain, cardiac muscle [... 637 0.0
gi|4417214|dbj|BAA36971.1| smooth muscle myosin heavy chain [Hom... 617 e-174
gi|4018|emb|CAA37894.1| myosin heavy chain type II [Saccharomyce... 612 e-173
gi|4016|emb|CAA29550.1| unnamed protein product [Saccharomyces c... 607 e-171
gi|28829494|gb|AAO52027.1| similar to Dictyostelium discoideum (... 597 e-168
gi|1709211|sp|P54697|MYSJ_DICDI Myosin IJ heavy chain >gnl|BL_OR... 593 e-167
gi|18652658|gb|AAD28718.2| myosin heavy chain A [Schmidtea medit... 589 e-166
gi|47207986|emb|CAF91457.1| unnamed protein product [Tetraodon n... 581 e-164
gi|39598344|emb|CAE69037.1| Hypothetical protein CBG15043 [Caeno... 580 e-163
gi|28277050|gb|AAH44834.1| Myh9 protein [Mus musculus] 574 e-161
gi|1589173|prf||2210342A myosin:SUBUNIT=heavy chain 573 e-161
gi|32566156|ref|NP_501620.2| myosin head and M protein repeat (... 565 e-159
gi|7509394|pir||T26467 hypothetical protein Y11D7A.14 - Caenorha... 558 e-157
gi|2209382|gb|AAB61475.1| slow myosin heavy chain 2 [Coturnix co... 544 e-153
gi|1083151|pir||S49119 embryonic/neonatal myosin heavy chain - r... 536 e-150
gi|37604192|gb|AAH59863.1| Myh10 protein [Mus musculus] 535 e-150
gi|36507|emb|CAA49154.1| smooth muscle mysosin heavy chain [Homo... 532 e-149
gi|50420349|ref|XP_458708.1| unnamed protein product [Debaryomyc... 531 e-149
gi|46444175|gb|EAL03452.1| hypothetical protein CaO19.5015 [Cand... 526 e-147
gi|127747|sp|P04461|MYH7_RABIT Myosin heavy chain, cardiac muscl... 525 e-147
gi|1039361|gb|AAA79858.1| myosin 523 e-146
gi|7441409|pir||T14279 myosin-like protein my5 - common sunflowe... 522 e-146
gi|8393817|ref|NP_058779.1| myosin 5B; Myosin of the dilute-myos... 519 e-145
gi|15221848|ref|NP_175858.1| myosin, putative [Arabidopsis thali... 519 e-145
gi|15240028|ref|NP_199203.1| myosin heavy chain (MYA2) [Arabidop... 518 e-145
gi|2129653|pir||S51824 myosin heavy chain MYA2 - Arabidopsis tha... 517 e-144
gi|6324902|ref|NP_014971.1| Type V myosin; plays a crucial role ... 515 e-144
gi|7489339|pir||T14276 myosin-like protein my2 - common sunflowe... 515 e-144
gi|42561681|ref|NP_171912.2| myosin family protein [Arabidopsis ... 513 e-143
gi|7441406|pir||T00957 myosin heavy chain F20D22.7 - Arabidopsis... 513 e-143
gi|46399202|ref|NP_963894.1| myosin Vb isoform 1 [Mus musculus] 512 e-143
gi|50287147|ref|XP_446003.1| unnamed protein product [Candida gl... 512 e-143
gi|28564980|gb|AAO32574.1| MYO2 [Saccharomyces kluyveri] 511 e-143
gi|11276958|pir||A59310 unconventional myosin heavy chain - maiz... 511 e-143
gi|42561814|ref|NP_172349.2| myosin heavy chain (PCR43) [Arabido... 511 e-142
gi|42569586|ref|NP_180882.2| myosin, putative [Arabidopsis thali... 509 e-142
gi|42567348|ref|NP_195046.3| myosin, putative [Arabidopsis thali... 508 e-142
gi|38091417|ref|XP_354617.1| similar to myosin heavy chain 2b [M... 506 e-141
gi|7243765|gb|AAF43440.1| unconventional myosin XI [Vallisneria ... 505 e-141
gi|47847739|dbj|BAD21517.1| putative myosin subfamily XI heavy c... 505 e-141
gi|47550963|ref|NP_999655.1| myosin V [Strongylocentrotus purpur... 504 e-141
gi|42567989|ref|NP_197549.3| myosin, putative [Arabidopsis thali... 504 e-140
gi|25295728|pir||A84743 probable myosin heavy chain [imported] -... 504 e-140
gi|48142183|ref|XP_397310.1| similar to ENSANGP00000021394 [Apis... 504 e-140
gi|13384201|gb|AAK21311.1| myosin subfamily XI heavy chain [Petr... 503 e-140
gi|45188227|ref|NP_984450.1| ADR354Wp [Eremothecium gossypii] >g... 503 e-140
gi|39932736|sp|Q9ULV0|MY5B_HUMAN Myosin Vb (Myosin 5B) 502 e-140
gi|29421190|dbj|BAA86433.2| KIAA1119 protein [Homo sapiens] 502 e-140
gi|42661400|ref|XP_371116.2| myosin VB [Homo sapiens] 502 e-140
gi|15219766|ref|NP_171954.1| myosin, putative [Arabidopsis thali... 502 e-140
gi|25295724|pir||F96587 hypothetical protein T22H22.1 [imported]... 501 e-140
gi|50302473|ref|XP_451171.1| unnamed protein product [Kluyveromy... 501 e-140
gi|42569537|ref|NP_180749.2| myosin family protein [Arabidopsis ... 500 e-139
gi|30685403|ref|NP_173201.2| myosin, putative [Arabidopsis thali... 499 e-139
gi|11276959|pir||B59254 mysoin heavy chain 12, splice form2 - hu... 499 e-139
gi|477266|pir||A48467 myosin heavy chain - nematode (Brugia mala... 499 e-139
gi|10835119|ref|NP_000250.1| myosin VA (heavy polypeptide 12, my... 499 e-139
gi|13431722|sp|Q9Y4I1|MY5A_HUMAN Myosin Va (Myosin 5A) (Dilute m... 499 e-139
gi|9055284|ref|NP_061198.1| myosin VC; myosin 5C [Homo sapiens] ... 498 e-139
gi|36957010|gb|AAQ87016.1| myosin heavy chain class XI E3 protei... 497 e-138
gi|104779|pir||S19188 myosin-V - chicken >gnl|BL_ORD_ID|145438 g... 497 e-138
gi|36956995|gb|AAQ87015.1| myosin heavy chain class XI E2 protei... 497 e-138
gi|37927130|pdb|1OE9|A Chain A, Crystal Structure Of Myosin V Mo... 497 e-138
gi|14626297|gb|AAK71565.1| putative myosin heavy chain, 3'-parti... 497 e-138
gi|46048699|ref|NP_990631.1| myosin I heavy chain isoform [Gallu... 497 e-138
gi|18087661|gb|AAL58953.1| putative myosin [Oryza sativa] 497 e-138
gi|36956980|gb|AAQ87014.1| myosin heavy chain class XI E1 protei... 497 e-138
gi|25295727|pir||E84726 probable unconventional myosin [imported... 496 e-138
gi|19075992|ref|NP_588492.1| putative myosin heavy chain [Schizo... 496 e-138
gi|50551775|ref|XP_503362.1| hypothetical protein [Yarrowia lipo... 495 e-138
gi|17737417|ref|NP_523571.1| CG7595-PB [Drosophila melanogaster]... 494 e-138
gi|40882425|gb|AAR96124.1| SD18415p [Drosophila melanogaster] 494 e-138
gi|26340098|dbj|BAC33712.1| unnamed protein product [Mus musculus] 494 e-138
gi|7441407|pir||T05200 myosin heavy chain F4I10.130 - Arabidopsi... 494 e-137
gi|6754784|ref|NP_034994.1| myosin Va; dilute lethal-20J protein... 494 e-137
gi|11358977|pir||A59249 class VII unconventional myosin - slime ... 493 e-137
gi|25295726|pir||D85390 myosin-like protein [imported] - Arabido... 493 e-137
gi|47208510|emb|CAF96455.1| unnamed protein product [Tetraodon n... 492 e-137
gi|227523|prf||1705299A myosin H 492 e-137
gi|28829995|gb|AAO52485.1| similar to Dictyostelium discoideum (... 492 e-137
gi|11559935|ref|NP_071514.1| myosin Va; myosin 5a; dilute-opisth... 491 e-137
gi|48133166|ref|XP_393334.1| similar to myosin heavy chain 2, mu... 491 e-137
gi|33416852|gb|AAH55517.1| Zgc:66156 protein [Danio rerio] 491 e-137
gi|49076368|ref|XP_402170.1| hypothetical protein UM04555.1 [Ust... 491 e-137
gi|6319290|ref|NP_009373.1| Required for mother-specific HO expr... 491 e-137
gi|34910550|ref|NP_916622.1| putative myosin heavy chain [Oryza ... 490 e-136
gi|15235408|ref|NP_194600.1| myosin heavy chain, putative [Arabi... 490 e-136
gi|7487964|pir||T04528 myosin heavy chain F16A16.180 - Arabidops... 489 e-136
gi|25295732|pir||F85334 myosin heavy chain-like protein (partial... 489 e-136
gi|15231004|ref|NP_188630.1| myosin (ATM) [Arabidopsis thaliana]... 488 e-136
gi|479413|pir||S33812 myosin-like protein ATM - Arabidopsis thal... 488 e-136
gi|20268744|gb|AAM14075.1| putative myosin [Arabidopsis thaliana] 488 e-136
gi|7441408|pir||T14278 myosin-like protein my4 - common sunflowe... 488 e-136
gi|46805521|dbj|BAD16972.1| putative myosin heavy chain [Oryza s... 488 e-135
gi|37535568|ref|NP_922086.1| putative myosin [Oryza sativa (japo... 484 e-135
gi|47214769|emb|CAG01035.1| unnamed protein product [Tetraodon n... 484 e-135
gi|50288415|ref|XP_446637.1| unnamed protein product [Candida gl... 484 e-135
gi|6472600|dbj|BAA87057.1| unconventional myosin heavy chain [Ch... 484 e-134
gi|9453839|dbj|BAB03273.1| myosin [Chara corallina] 484 e-134
gi|19113025|ref|NP_596233.1| putative myosin heavy chain [Schizo... 484 e-134
gi|25295725|pir||F86178 hypothetical protein [imported] - Arabid... 483 e-134
gi|42562644|ref|NP_175453.2| myosin family protein [Arabidopsis ... 482 e-134
gi|42569181|ref|NP_179619.2| myosin, putative [Arabidopsis thali... 481 e-134
gi|25295729|pir||D84587 probable myosin heavy chain [imported] -... 481 e-134
gi|31237908|ref|XP_319689.1| ENSANGP00000021394 [Anopheles gambi... 481 e-134
gi|8778462|gb|AAF79470.1| F1L3.28 [Arabidopsis thaliana] 481 e-134
gi|31217856|ref|XP_316519.1| ENSANGP00000013495 [Anopheles gambi... 480 e-133
gi|940860|emb|CAA62184.1| orf 06167 [Saccharomyces cerevisiae] 480 e-133
gi|17568553|ref|NP_508420.1| heavy chain, Unconventional Myosin ... 478 e-132
gi|39591114|emb|CAE58894.1| Hypothetical protein CBG02140 [Caeno... 477 e-132
gi|27806009|ref|NP_776819.1| myosin X [Bos taurus] >gnl|BL_ORD_I... 477 e-132
gi|4249742|gb|AAD13782.1| myosin II heavy chain [Ilyanassa obsol... 476 e-132
gi|50428778|gb|AAT77099.1| myosin 10 [Xenopus laevis] 476 e-132
gi|50872470|gb|AAT85070.1| myosin heavy chain class XI E3 protei... 476 e-132
gi|15230968|ref|NP_191375.1| myosin heavy chain, putative [Arabi... 476 e-132
gi|31193918|gb|AAP44753.1| putative myosin heavy chain [Oryza sa... 476 e-132
gi|49130864|ref|XP_412999.1| hypothetical protein AN8862.2 [Aspe... 475 e-132
gi|37534010|ref|NP_921307.1| putative myosin heavy chain [Oryza ... 475 e-132
gi|48130443|ref|XP_393314.1| similar to ENSANGP00000013495 [Apis... 475 e-132
gi|38109385|gb|EAA55266.1| hypothetical protein MG06923.4 [Magna... 473 e-131
gi|24586273|ref|NP_724570.1| CG2146-PB [Drosophila melanogaster]... 473 e-131
gi|7441410|pir||T13939 myosin V - fruit fly (Drosophila melanoga... 473 e-131
gi|17137244|ref|NP_477186.1| CG2146-PA [Drosophila melanogaster]... 473 e-131
gi|11276961|pir||A59311 myosin VIII, ZMM3 - maize (fragment) >gn... 470 e-130
gi|33589410|gb|AAQ22472.1| RE30195p [Drosophila melanogaster] 469 e-130
gi|24586270|ref|NP_724569.1| CG2146-PC [Drosophila melanogaster]... 469 e-130
gi|24582545|ref|NP_723294.1| CG6976-PB [Drosophila melanogaster]... 469 e-130
gi|24582547|ref|NP_723295.1| CG6976-PC [Drosophila melanogaster]... 469 e-130
gi|33589316|gb|AAQ22425.1| RH39293p [Drosophila melanogaster] 469 e-130
gi|11359838|pir||A59233 myosin VII-like protein - fruit fly (Dro... 468 e-130
gi|24582549|ref|NP_652630.2| CG6976-PA [Drosophila melanogaster]... 468 e-130
gi|24582551|ref|NP_723296.1| CG6976-PD [Drosophila melanogaster]... 468 e-130
gi|1929038|emb|CAA69352.1| dilute class unconventional myosin [D... 468 e-129
gi|2129651|pir||S51823 myosin heavy chain ATM2 - Arabidopsis tha... 468 e-129
gi|28950352|emb|CAD70976.1| probable myosin MYO2 [Neurospora cra... 468 e-129
gi|50731470|ref|XP_417277.1| PREDICTED: similar to myosin VIIA [... 467 e-129
gi|32414799|ref|XP_327879.1| hypothetical protein [Neurospora cr... 466 e-129
gi|46126183|ref|XP_387645.1| conserved hypothetical protein [Gib... 466 e-129
gi|7416982|gb|AAF62394.1| myosin heavy chain cardiac muscle spec... 466 e-129
gi|7416983|gb|AAF62395.1| myosin heavy chain cardiac muscle spec... 466 e-129
gi|7416980|gb|AAF62392.1| myosin heavy chain catch (smooth) musc... 466 e-129
gi|36956948|gb|AAQ87012.1| myosin heavy chain class VIII A1 prot... 465 e-129
gi|36956965|gb|AAQ87013.1| myosin heavy chain class VIII A2 prot... 465 e-129
gi|7416979|gb|AAF62391.1| myosin heavy chain striated muscle spe... 464 e-128
gi|9759501|dbj|BAB10751.1| myosin heavy chain [Arabidopsis thali... 463 e-128
gi|42568525|ref|NP_568806.3| myosin heavy chain, putative [Arabi... 462 e-128
gi|7441405|pir||T07961 myosin heavy chain - Chlamydomonas reinha... 461 e-127
gi|27529740|dbj|BAA34519.2| KIAA0799 protein [Homo sapiens] 461 e-127
gi|2119290|pir||I52863 myosin heavy chain (MHC) - mouse (fragmen... 460 e-127
gi|1019445|gb|AAC50218.1| Myosin-VIIa >gnl|BL_ORD_ID|1396958 gi|... 460 e-127
gi|23618899|ref|NP_703203.1| myosin VIIA (Usher syndrome 1B (aut... 460 e-127
gi|4505307|ref|NP_000251.1| myosin VIIA; deafness, autosomal dom... 460 e-127
gi|7498293|pir||T30148 hypothetical protein E02C12.1 - Caenorhab... 460 e-127
gi|11037057|ref|NP_036466.1| myosin X [Homo sapiens] >gnl|BL_ORD... 460 e-127
gi|17433142|sp|Q9HD67|MY10_HUMAN Myosin X 460 e-127
gi|37859221|gb|AAR04675.1| Heavy chain, unconventional myosin pr... 460 e-127
gi|35215302|ref|NP_694515.1| myosin VIIa [Danio rerio] >gnl|BL_O... 460 e-127
gi|32567045|ref|NP_505433.2| heavy chain, Unconventional Myosin ... 460 e-127
gi|7108753|gb|AAF36524.1| myosin X [Homo sapiens] 459 e-127
gi|13124361|sp|Q9UKN7|MY15_HUMAN Myosin XV (Unconventional myosi... 459 e-127
gi|9944237|emb|CAC05419.1| myosin VIIA [Danio rerio] 459 e-127
gi|50755609|ref|XP_414818.1| PREDICTED: similar to unconventiona... 459 e-127
gi|22547229|ref|NP_057323.2| myosin XV; unconventional myosin-15... 459 e-127
gi|9910111|gb|AAF68025.2| myosin X [Homo sapiens] 459 e-127
gi|44889481|ref|NP_036355.2| myosin IB; myosin-I alpha [Homo sap... 458 e-127
gi|31565495|gb|AAH53558.1| MYO1B protein [Homo sapiens] 458 e-127
gi|11360310|pir||A59255 myosin VIIa, long form - human >gnl|BL_O... 458 e-127
gi|11360311|pir||A59257 myosin VIIa, short form - human >gnl|BL_... 458 e-127
gi|7489338|pir||T14275 myosin-like protein my1 - common sunflowe... 457 e-126
gi|9506909|ref|NP_062345.1| myosin X; myosin-X [Mus musculus] >g... 457 e-126
gi|39594588|emb|CAE72166.1| Hypothetical protein CBG19269 [Caeno... 456 e-126
gi|25295730|pir||G96539 hypothetical protein F14I3.6 [imported] ... 455 e-126
gi|27529734|dbj|BAA34447.2| KIAA0727 protein [Homo sapiens] 454 e-125
gi|112999|sp|P22467|MYSA_DICDI Myosin IA heavy chain (Myosin-lik... 454 e-125
gi|32172416|sp|O94832|MY1D_HUMAN Myosin Id 454 e-125
gi|27882064|gb|AAH44718.1| LOC398527 protein [Xenopus laevis] 454 e-125
gi|50416440|gb|AAH77774.1| LOC398527 protein [Xenopus laevis] 454 e-125
gi|25573172|gb|AAN75148.1| MYO2 [Cryptococcus neoformans var. gr... 454 e-125
gi|47211881|emb|CAF91177.1| unnamed protein product [Tetraodon n... 454 e-125
gi|2961227|gb|AAC98089.1| myosin IC heavy chain [Acanthamoeba ca... 453 e-125
gi|6678994|ref|NP_032689.1| myosin VIIa; shaker 1 [Mus musculus]... 453 e-125
gi|48095394|ref|XP_394436.1| similar to ENSANGP00000014167 [Apis... 452 e-125
gi|32816170|gb|AAP88402.1| myosin XVA isoform 1a [Mus musculus] 452 e-125
gi|41281977|ref|NP_874357.1| myosin XV isoform 2a; shaker 2; myo... 452 e-125
gi|25777801|gb|AAN75607.1| MYO2 [Cryptococcus neoformans var. ne... 452 e-125
gi|28893569|ref|NP_796364.1| RIKEN cDNA 9930104H07 gene [Mus mus... 452 e-125
gi|6754780|ref|NP_034992.1| myosin XV; shaker 2; myosin XVA [Mus... 452 e-125
gi|7513867|pir||T42386 unconventional myosin 15 - mouse (fragmen... 451 e-125
gi|32452000|gb|AAH54786.1| Myo1b protein [Mus musculus] 451 e-124
gi|13432181|sp|P46735|MY1B_MOUSE Myosin Ib (Myosin I alpha) (MMI... 451 e-124
gi|28277386|gb|AAH46300.1| Myo1b protein [Mus musculus] 451 e-124
gi|47229940|emb|CAG10354.1| unnamed protein product [Tetraodon n... 451 e-124
gi|38014454|gb|AAH60477.1| MGC68653 protein [Xenopus laevis] 451 e-124
>gi|25150354|ref|NP_508504.2| non-muscle myosin (nmy-1)
[Caenorhabditis elegans]
gi|21629508|gb|AAA83339.2| Non-muscle myosin protein 1
[Caenorhabditis elegans]
Length = 1963
Score = 3495 bits (9063), Expect = 0.0
Identities = 1821/1963 (92%), Positives = 1821/1963 (92%)
Frame = +1
Query: 1 MGDLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSR 180
MGDLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSR
Sbjct: 1 MGDLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSR 60
Query: 181 QVTISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINP 360
QVTISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINP
Sbjct: 61 QVTISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINP 120
Query: 361 YKKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTEN 540
YKKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTEN
Sbjct: 121 YKKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTEN 180
Query: 541 TKKVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKT 720
TKKVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKT
Sbjct: 181 TKKVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKT 240
Query: 721 VKNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSA 900
VKNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSA
Sbjct: 241 VKNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSA 300
Query: 901 KEKSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAV 1080
KEKSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAV
Sbjct: 301 KEKSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAV 360
Query: 1081 LLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQN 1260
LLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQN
Sbjct: 361 LLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQN 420
Query: 1261 QEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQ 1440
QEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQ
Sbjct: 421 QEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQ 480
Query: 1441 ICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLD 1620
ICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLD
Sbjct: 481 ICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLD 540
Query: 1621 EECLFPKANDKSFVEKLQKTHNKHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMD 1800
EECLFPKANDKSFVEKLQKTHNKHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMD
Sbjct: 541 EECLFPKANDKSFVEKLQKTHNKHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMD 600
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQL 1980
PLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQL
Sbjct: 601 PLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQL 660
Query: 1981 TKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPF 2160
TKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPF
Sbjct: 661 TKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPF 720
Query: 2161 QEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEE 2340
QEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEE
Sbjct: 721 QEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEE 780
Query: 2341 RDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKV 2520
RDLKLTALIMNFQAQCRGFLSRRLYT NGLAYLKLRNWQWWRLFTKV
Sbjct: 781 RDLKLTALIMNFQAQCRGFLSRRLYTRRQQQSSAIRIIQRNGLAYLKLRNWQWWRLFTKV 840
Query: 2521 KPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESE 2700
KPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESE
Sbjct: 841 KPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESE 900
Query: 2701 NSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXX 2880
NSAELDDIRGRLQTRNQELEYIVNDMRDRLS RRKQMETVRD
Sbjct: 901 NSAELDDIRGRLQTRNQELEYIVNDMRDRLSEEEQQNEKNNDERRKQMETVRDLEEQLEQ 960
Query: 2881 XXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEER 3060
DKTNVDQ QDAYD GLTTQLLDHEER
Sbjct: 961 EEQARQKLLLDKTNVDQRLRNLEERLVELQDAYDKLLKEKRLLEEKVEGLTTQLLDHEER 1020
Query: 3061 AKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEEL 3240
AKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEEL
Sbjct: 1021 AKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEEL 1080
Query: 3241 NNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTR 3420
NNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTR
Sbjct: 1081 NNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTR 1140
Query: 3421 REVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKF 3600
REVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKF
Sbjct: 1141 REVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKF 1200
Query: 3601 SRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHL 3780
SRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHL
Sbjct: 1201 SRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHL 1260
Query: 3781 MEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXX 3960
MEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATA
Sbjct: 1261 MEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAEGQIQELN 1320
Query: 3961 XXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAE 4140
TRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAE
Sbjct: 1321 EQIQEETRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAE 1380
Query: 4141 ESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASH 4320
ESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASH
Sbjct: 1381 ESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASH 1440
Query: 4321 RDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESD 4500
RDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESD
Sbjct: 1441 RDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESD 1500
Query: 4501 RVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARL 4680
RVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARL
Sbjct: 1501 RVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARL 1560
Query: 4681 RLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIE 4860
RLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIE
Sbjct: 1561 RLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIE 1620
Query: 4861 NQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFR 5040
NQIGELEQQLEVANRLKEEY EYQIECEEARQAKEDIAALLREADRKFR
Sbjct: 1621 NQIGELEQQLEVANRLKEEYNKQLKKNQQIIKEYQIECEEARQAKEDIAALLREADRKFR 1680
Query: 5041 AVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXX 5220
AVEAEREQLREANEGLMQARKQ RAKGGGISSEEKRRLEAKIAQ
Sbjct: 1681 AVEAEREQLREANEGLMQARKQLELENDELEELRAKGGGISSEEKRRLEAKIAQLEEELE 1740
Query: 5221 XXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES 5400
QSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES
Sbjct: 1741 EEQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES 1800
Query: 5401 GAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANE 5580
GAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANE
Sbjct: 1801 GAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANE 1860
Query: 5581 QAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMNXXX 5760
QAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN
Sbjct: 1861 QAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMNLRG 1920
Query: 5761 XXXXXXXXXXXXXFDVPGSSDNLARXXXXXXXXXXXXHGMSVN 5889
FDVPGSSDNLAR HGMSVN
Sbjct: 1921 NNRRRADMRLRRGFDVPGSSDNLAREEENESNVSGSEHGMSVN 1963
>gi|7441404|pir||T16416 hypothetical protein F52B10.1 - Caenorhabditis
elegans
Length = 1956
Score = 3473 bits (9006), Expect = 0.0
Identities = 1814/1963 (92%), Positives = 1814/1963 (92%)
Frame = +1
Query: 1 MGDLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSR 180
MGDLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSR
Sbjct: 1 MGDLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSR 60
Query: 181 QVTISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINP 360
QVTISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINP
Sbjct: 61 QVTISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINP 120
Query: 361 YKKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTEN 540
YKKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTEN
Sbjct: 121 YKKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTEN 180
Query: 541 TKKVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKT 720
TKKVIQYLAHVAGATRNKSLNAAAQQNIVQK GELEHQLLQANPILEAFGNSKT
Sbjct: 181 TKKVIQYLAHVAGATRNKSLNAAAQQNIVQK-------GELEHQLLQANPILEAFGNSKT 233
Query: 721 VKNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSA 900
VKNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSA
Sbjct: 234 VKNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSA 293
Query: 901 KEKSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAV 1080
KEKSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAV
Sbjct: 294 KEKSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAV 353
Query: 1081 LLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQN 1260
LLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQN
Sbjct: 354 LLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQN 413
Query: 1261 QEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQ 1440
QEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQ
Sbjct: 414 QEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQ 473
Query: 1441 ICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLD 1620
ICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLD
Sbjct: 474 ICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLD 533
Query: 1621 EECLFPKANDKSFVEKLQKTHNKHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMD 1800
EECLFPKANDKSFVEKLQKTHNKHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMD
Sbjct: 534 EECLFPKANDKSFVEKLQKTHNKHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMD 593
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQL 1980
PLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQL
Sbjct: 594 PLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQL 653
Query: 1981 TKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPF 2160
TKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPF
Sbjct: 654 TKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPF 713
Query: 2161 QEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEE 2340
QEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEE
Sbjct: 714 QEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEE 773
Query: 2341 RDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKV 2520
RDLKLTALIMNFQAQCRGFLSRRLYT NGLAYLKLRNWQWWRLFTKV
Sbjct: 774 RDLKLTALIMNFQAQCRGFLSRRLYTRRQQQSSAIRIIQRNGLAYLKLRNWQWWRLFTKV 833
Query: 2521 KPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESE 2700
KPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESE
Sbjct: 834 KPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESE 893
Query: 2701 NSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXX 2880
NSAELDDIRGRLQTRNQELEYIVNDMRDRLS RRKQMETVRD
Sbjct: 894 NSAELDDIRGRLQTRNQELEYIVNDMRDRLSEEEQQNEKNNDERRKQMETVRDLEEQLEQ 953
Query: 2881 XXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEER 3060
DKTNVDQ QDAYD GLTTQLLDHEER
Sbjct: 954 EEQARQKLLLDKTNVDQRLRNLEERLVELQDAYDKLLKEKRLLEEKVEGLTTQLLDHEER 1013
Query: 3061 AKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEEL 3240
AKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEEL
Sbjct: 1014 AKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEEL 1073
Query: 3241 NNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTR 3420
NNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTR
Sbjct: 1074 NNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTR 1133
Query: 3421 REVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKF 3600
REVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKF
Sbjct: 1134 REVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKF 1193
Query: 3601 SRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHL 3780
SRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHL
Sbjct: 1194 SRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHL 1253
Query: 3781 MEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXX 3960
MEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATA
Sbjct: 1254 MEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAEGQIQELN 1313
Query: 3961 XXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAE 4140
TRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAE
Sbjct: 1314 EQIQEETRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAE 1373
Query: 4141 ESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASH 4320
ESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASH
Sbjct: 1374 ESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASH 1433
Query: 4321 RDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESD 4500
RDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESD
Sbjct: 1434 RDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESD 1493
Query: 4501 RVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARL 4680
RVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARL
Sbjct: 1494 RVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARL 1553
Query: 4681 RLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIE 4860
RLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIE
Sbjct: 1554 RLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIE 1613
Query: 4861 NQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFR 5040
NQIGELEQQLEVANRLKEEY EYQIECEEARQAKEDIAALLREADRKFR
Sbjct: 1614 NQIGELEQQLEVANRLKEEYNKQLKKNQQIIKEYQIECEEARQAKEDIAALLREADRKFR 1673
Query: 5041 AVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXX 5220
AVEAEREQLREANEGLMQARKQ RAKGGGISSEEKRRLEAKIAQ
Sbjct: 1674 AVEAEREQLREANEGLMQARKQLELENDELEELRAKGGGISSEEKRRLEAKIAQLEEELE 1733
Query: 5221 XXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES 5400
QSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES
Sbjct: 1734 EEQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES 1793
Query: 5401 GAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANE 5580
GAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANE
Sbjct: 1794 GAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANE 1853
Query: 5581 QAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMNXXX 5760
QAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN
Sbjct: 1854 QAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMNLRG 1913
Query: 5761 XXXXXXXXXXXXXFDVPGSSDNLARXXXXXXXXXXXXHGMSVN 5889
FDVPGSSDNLAR HGMSVN
Sbjct: 1914 NNRRRADMRLRRGFDVPGSSDNLAREEENESNVSGSEHGMSVN 1956
>gi|39591036|emb|CAE58816.1| Hypothetical protein CBG02025
[Caenorhabditis briggsae]
Length = 1964
Score = 3310 bits (8582), Expect = 0.0
Identities = 1714/1964 (87%), Positives = 1770/1964 (89%), Gaps = 1/1964 (0%)
Frame = +1
Query: 1 MGDLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSR 180
MGDLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFL GSIK+E+NDE LVEL D+ R
Sbjct: 1 MGDLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLFGSIKKESNDEFLVELCDSGR 60
Query: 181 QVTISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINP 360
QVTISRDDVQKANPPKFDKIEDMSELTYLNEASVL+NLK+RYYSSLIYTYSGLFCVVINP
Sbjct: 61 QVTISRDDVQKANPPKFDKIEDMSELTYLNEASVLNNLKERYYSSLIYTYSGLFCVVINP 120
Query: 361 YKKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTEN 540
YKKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTEN
Sbjct: 121 YKKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTEN 180
Query: 541 TKKVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKT 720
TKKVIQYLAHVAGATRNK ++AA QNIVQKPD RNPIGELE+QLLQANPILEAFGNSKT
Sbjct: 181 TKKVIQYLAHVAGATRNKGMSAAVAQNIVQKPDTRNPIGELENQLLQANPILEAFGNSKT 240
Query: 721 VKNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSA 900
VKNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQ+ DERSFHIFYQILRGCSA
Sbjct: 241 VKNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQSPDERSFHIFYQILRGCSA 300
Query: 901 KEKSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAV 1080
KEKSEYLLE VDNYRFLVN GITLPNVDDVQEFHST+NSM+IMGFAD+EISSI+RVVSA+
Sbjct: 301 KEKSEYLLETVDNYRFLVNHGITLPNVDDVQEFHSTLNSMKIMGFADEEISSILRVVSAI 360
Query: 1081 LLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQN 1260
LLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQN
Sbjct: 361 LLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQN 420
Query: 1261 QEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQ 1440
QEQAEFAVEAIAKA YERLFKWLV RINKSLDRTHRQGASFIGILDIAGFEIF NSFEQ
Sbjct: 421 QEQAEFAVEAIAKACYERLFKWLVNRINKSLDRTHRQGASFIGILDIAGFEIFQTNSFEQ 480
Query: 1441 ICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLD 1620
CINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLD
Sbjct: 481 FCINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLD 540
Query: 1621 EECLFPKANDKSFVEKLQKTHNKHPKFIVPDMRSKS-HFAVVHYAGRVDYSADQWLMKNM 1797
EECLFPKANDK+FVEKLQKTH KHPKFI ++R+++ FAVVHYAGRVDYSADQWLMKNM
Sbjct: 541 EECLFPKANDKTFVEKLQKTHIKHPKFIPAELRNRTGDFAVVHYAGRVDYSADQWLMKNM 600
Query: 1798 DPLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQ 1977
DPLNENVVGLMQNSTD FVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQ
Sbjct: 601 DPLNENVVGLMQNSTDSFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQ 660
Query: 1978 LTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVP 2157
LTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVL+QLRCNGVLEGIRICRQGFPNRVP
Sbjct: 661 LTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLDQLRCNGVLEGIRICRQGFPNRVP 720
Query: 2158 FQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEE 2337
FQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDID+NLYRIGQSKVFFRTGVLAHLEE
Sbjct: 721 FQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDSNLYRIGQSKVFFRTGVLAHLEE 780
Query: 2338 ERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTK 2517
ERDLKLTALI NFQAQCRGFLSRRLYT NGLAYLKLRNWQWWRLFTK
Sbjct: 781 ERDLKLTALIQNFQAQCRGFLSRRLYTRRQQQSSAIRIIQRNGLAYLKLRNWQWWRLFTK 840
Query: 2518 VKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQES 2697
VKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQES
Sbjct: 841 VKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQES 900
Query: 2698 ENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXX 2877
+NSAEL+DIR RLQTRNQELEYIVNDMRDRLS RRKQMETVRD
Sbjct: 901 DNSAELEDIRSRLQTRNQELEYIVNDMRDRLSEEEQQNEKNNEERRKQMETVRDLEEQLE 960
Query: 2878 XXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEE 3057
DKTNVDQ QDAYD LTTQLLDHEE
Sbjct: 961 QEEQARQKLLLDKTNVDQRLRNLEERLVELQDAYDKLLKEKKLLEEKVEALTTQLLDHEE 1020
Query: 3058 RAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEE 3237
RAKHG+KAKGRLENQLHELEQDLNRERQ+KSE+EQ KRKLLAELEDSKDHL EKMGKVEE
Sbjct: 1021 RAKHGIKAKGRLENQLHELEQDLNRERQFKSEIEQQKRKLLAELEDSKDHLVEKMGKVEE 1080
Query: 3238 LNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMT 3417
LNNQL+KRDEELQ QLT+YDEESA V +MQKQMRDMQTTIDELRED+ETERNARNKAEMT
Sbjct: 1081 LNNQLIKRDEELQLQLTKYDEESAAVAVMQKQMRDMQTTIDELREDIETERNARNKAEMT 1140
Query: 3418 RREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAK 3597
RREVVAQLEKVKGDVLDKVDEATMLQDLM+RKDEEVNATKR IEQIQH ME KIE+QK K
Sbjct: 1141 RREVVAQLEKVKGDVLDKVDEATMLQDLMARKDEEVNATKRTIEQIQHAMEAKIEDQKQK 1200
Query: 3598 FSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAH 3777
FS Q+E LH+QIEQHKKQR+QLEKQQN ADQERADMAQEIALLQASRA+IDKKRKIHEAH
Sbjct: 1201 FSHQIEGLHEQIEQHKKQRNQLEKQQNLADQERADMAQEIALLQASRAEIDKKRKIHEAH 1260
Query: 3778 LMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXX 3957
LMEIQANL+ESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLA A
Sbjct: 1261 LMEIQANLSESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLAAAEGTIQEL 1320
Query: 3958 XXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKA 4137
TRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAG+ARRKA
Sbjct: 1321 NEQIQEETRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGDARRKA 1380
Query: 4138 EESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRAS 4317
EE+VNQQLEELRKKNLRDVEHLQ+QLEESE KERILQSKKKIQQE ED +MEL+NVRAS
Sbjct: 1381 EEAVNQQLEELRKKNLRDVEHLQQQLEESEAVKERILQSKKKIQQEFEDVAMELDNVRAS 1440
Query: 4318 HRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEES 4497
HRDSEKRQKKFE+QMAEER AVQKALLDRD+MSQELRDRETRVLSL+NEVD+MKE LEES
Sbjct: 1441 HRDSEKRQKKFETQMAEERAAVQKALLDRDSMSQELRDRETRVLSLMNEVDLMKEQLEES 1500
Query: 4498 DRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDAR 4677
DR+RRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAEL DMR QMEELEDNLQ+AEDAR
Sbjct: 1501 DRIRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELADMRAQMEELEDNLQMAEDAR 1560
Query: 4678 LRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKI 4857
LRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKI
Sbjct: 1561 LRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKI 1620
Query: 4858 ENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKF 5037
ENQIGELEQQLEVANRLKEEY EYQIECEEARQAKEDIAA LREADRKF
Sbjct: 1621 ENQIGELEQQLEVANRLKEEYNKQLKKNQQIIKEYQIECEEARQAKEDIAAQLREADRKF 1680
Query: 5038 RAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXX 5217
RAVEAEREQLREANEGLMQARK RAKGGGISSEEKRRLEAKI+Q
Sbjct: 1681 RAVEAEREQLREANEGLMQARKLLELENDELEELRAKGGGISSEEKRRLEAKISQLEEEL 1740
Query: 5218 XXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELE 5397
QSNCELAIDKQRKAQVQLEQ+TTDLSMERTLNQKT+AEKQSLER+ RDYKAKITELE
Sbjct: 1741 EEEQSNCELAIDKQRKAQVQLEQVTTDLSMERTLNQKTDAEKQSLERTCRDYKAKITELE 1800
Query: 5398 SGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRAN 5577
SGAQSRARAQMAALEAK+QYLEDQLN EGQEKTAANRAARRLEKRLND TQQFEDEKRAN
Sbjct: 1801 SGAQSRARAQMAALEAKIQYLEDQLNAEGQEKTAANRAARRLEKRLNDITQQFEDEKRAN 1860
Query: 5578 EQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMNXX 5757
EQAKELLEKSNLKNRNLRRQLDE EDE+SRERTKHRNVQREADDLLDANEQLTRELMN
Sbjct: 1861 EQAKELLEKSNLKNRNLRRQLDETEDEISRERTKHRNVQREADDLLDANEQLTRELMNLR 1920
Query: 5758 XXXXXXXXXXXXXXFDVPGSSDNLARXXXXXXXXXXXXHGMSVN 5889
FDVPGS+DNLAR HGMSVN
Sbjct: 1921 GNNRRRADMRLRRGFDVPGSNDNLAREDENESNVSGSEHGMSVN 1964
>gi|31198813|ref|XP_308354.1| ENSANGP00000024069 [Anopheles gambiae]
gi|30178669|gb|EAA45414.1| ENSANGP00000024069 [Anopheles gambiae str.
PEST]
Length = 1993
Score = 1868 bits (4838), Expect = 0.0
Identities = 960/1927 (49%), Positives = 1324/1927 (67%), Gaps = 14/1927 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
+L+YL V+R + DPAT A W Q++L WVP +++GF+ SIK E DEV VEL +T ++V
Sbjct: 25 ELKYLSVERNSFNDPATQAEWTQKRLVWVPHESQGFVAASIKGERGDEVEVELAETGKRV 84
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
+ +DD+QK NPPKFDK+EDM+ELT LNEASVLHN+KDRYYS LIYTYSGLFCVV+NPYK
Sbjct: 85 LVLKDDIQKMNPPKFDKVEDMAELTCLNEASVLHNIKDRYYSGLIYTYSGLFCVVVNPYK 144
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
KLPIY+E ++E++KG KRHE+PPH+FAI DTAYRSMLQ+REDQSILCTGESGAGKTENTK
Sbjct: 145 KLPIYTEKIMEKYKGIKRHEVPPHVFAITDTAYRSMLQDREDQSILCTGESGAGKTENTK 204
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQN---------IVQKPDVRNPIGELEHQLLQANPILE 699
KVIQYLA+VA + S+ + ++ V GELE QLLQANPILE
Sbjct: 205 KVIQYLAYVAASKPKGSVAVGVGCSFSLLIYLLFLLLSHHVWT--GELEQQLLQANPILE 262
Query: 700 AFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQ 879
AFGN+KTVKNDNSSRFGKFIRINFD SGYISGANIE YLLEKSR +RQA+DER+FHIFYQ
Sbjct: 263 AFGNAKTVKNDNSSRFGKFIRINFDASGYISGANIETYLLEKSRAIRQAKDERTFHIFYQ 322
Query: 880 ILRGCSAKEKSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSI 1059
+L G S +++ ++L+ V Y FL N G+ +P VDD EF +T+ SM IMG ++ +SI
Sbjct: 323 LLAGASPEQRERFILDDVKTYPFLSNGGLPVPGVDDYAEFQATVKSMNIMGMTSEDFNSI 382
Query: 1060 MRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGRE 1239
R+VSAVLL G++ F QE+ SDQA L D+ V QK+ HLLGL V ++ KAFL PRIKVGR+
Sbjct: 383 FRIVSAVLLFGSMTFKQERNSDQATLPDNTVAQKIAHLLGLNVTDMTKAFLTPRIKVGRD 442
Query: 1240 FVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIF 1419
FV KAQ +EQ EFAVEAIAKA YE++FKWLV RIN+SLDRT RQGASFIGILD+AGFEIF
Sbjct: 443 FVTKAQTREQVEFAVEAIAKACYEKMFKWLVNRINRSLDRTKRQGASFIGILDMAGFEIF 502
Query: 1420 DINSFEQICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM 1599
++NSFEQ+CINYTNEKLQQLFN+TMFILEQEEYQREGIEW FIDFGLDLQPTIDLI+KP
Sbjct: 503 ELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWKFIDFGLDLQPTIDLIDKPG 562
Query: 1600 GVLALLDEECLFPKANDKSFVEKLQKTHNKHPKFIVPDMRSKSHFAVVHYAGRVDYSADQ 1779
G++ALLDEEC FPKA DKSFVEKL H+ HPKF+ D R + FAVVHYAG+VDYSA +
Sbjct: 563 GIMALLDEECWFPKATDKSFVEKLAAAHSMHPKFMKTDFRGVADFAVVHYAGKVDYSATK 622
Query: 1780 WLMKNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVS 1959
WLMKNMDPLNENVV L+Q S DPFV IWKDAE G+ + +T FG R+RKGMFRTVS
Sbjct: 623 WLMKNMDPLNENVVSLLQASQDPFVVQIWKDAEIVGMAQQALTDTQFGARTRKGMFRTVS 682
Query: 1960 QLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQG 2139
L+KEQL KLM TLRNT+P+FVRCIIPNHEK++GKI++ LVL+QLRCNGVLEGIRICRQG
Sbjct: 683 HLYKEQLAKLMDTLRNTNPNFVRCIIPNHEKRAGKIDAPLVLDQLRCNGVLEGIRICRQG 742
Query: 2140 FPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGV 2319
FPNR+PFQEFR RYE+LTP+VIPK F+DGK + +MI +L++D+NLYRIGQSK+FFR GV
Sbjct: 743 FPNRIPFQEFRQRYELLTPNVIPKGFMDGKRACEQMIKSLELDSNLYRIGQSKIFFRAGV 802
Query: 2320 LAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQW 2499
LAHLEEERD K+T LI+NFQA CRGFL+RR Y N AYLKLRNWQW
Sbjct: 803 LAHLEEERDYKITDLIVNFQAFCRGFLARRNYQKRLQQLNAIRIIQRNCAAYLKLRNWQW 862
Query: 2500 WRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQE 2679
WRL+TKVKPLL+VT+ ++++ K+DELR +++L + + +E EKK Q + E+ + E
Sbjct: 863 WRLYTKVKPLLEVTKQEEKLVQKEDELRQIRDKLENLSKNSQEYEKKYQQAMEEKTHLAE 922
Query: 2680 QLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRD 2859
QLQ E E AE ++ R RL R QELE ++ D+ R+ ++K ++D
Sbjct: 923 QLQAEIELCAEAEEGRARLVARKQELEELMQDLESRIEEEEERVNALTSEKKKLQINIQD 982
Query: 2860 XXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQ 3039
+K +D +D L+
Sbjct: 983 LEEQLEEEEAARQKLQLEKVQLDAKLKKMEEDVALIEDQNHKLVKEKKLLEERANDLSQT 1042
Query: 3040 LLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEK 3219
L + EE+AKH K K + E+ + ELE+ L ++ Q + E ++ KRK+ E+ D K+ + E+
Sbjct: 1043 LAEEEEKAKHLAKLKVKHESTIAELEERLLKDHQQRQEADRSKRKIETEVADLKEQINER 1102
Query: 3220 MGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNAR 3399
++EE+ QL+KR+EEL L R DEESA QK R++++ + E++ED+E E+ AR
Sbjct: 1103 RMQIEEMQQQLVKREEELAQTLVRIDEESAAKAAAQKTQRELESQLAEIQEDLEAEKLAR 1162
Query: 3400 NKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKI 3579
+KAE +R++ +LE +K ++LD +D Q+L S++++EV K+ +E E +
Sbjct: 1163 SKAEKQKRDLNEELEALKNELLDSLDTTAAQQELRSKREQEVATLKKTLEDESANHESTL 1222
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKR 3759
+ + K ++++ +++Q+E KK + LEK + Q + E AD+A E+ + SR + D++R
Sbjct: 1223 MDMRHKHAQEISSINEQLENLKKMKGGLEKSKQQLEAENADLATELRNVNQSRQENDRRR 1282
Query: 3760 KIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAX 3939
K E + E+Q LA+ D + L D++ + + E +++ + +E E + +
Sbjct: 1283 KQAETQIAELQVKLADVDRVRVELQDKVTKLQQESENITQQLDEAELKASAAIKSAGNLE 1342
Query: 3940 XXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAG 4119
TR K+A ++ RQ+E EK AL ++ EE E + + EK++
Sbjct: 1343 SQLTEAQQLLEEETRQKLALSSKLRQIESEKEALQEQLEEDEEAKTNYEKKLAELNFTIQ 1402
Query: 4120 EARRKAEE--SVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSM 4293
E ++++EE + ++LEE +KK +D+E LQ+Q++E + A +R+ +SKKKIQ ELED+++
Sbjct: 1403 EMKKRSEEDSDIAKELEESKKKMNKDIETLQRQIQELQAANDRLDKSKKKIQSELEDATI 1462
Query: 4294 ELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDI 4473
EL+ R + EK+QK F+ +AEE+ ++ +RDA +E R++ET+VLSL E+D
Sbjct: 1463 ELDTQRTKVLELEKKQKNFDKVLAEEKAISEQVAQERDAAEREAREKETKVLSLTRELDE 1522
Query: 4474 MKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDN 4653
E ++E + R+ LQ EL + + + KNVHELEKAKR+LE++L +++ Q EELED+
Sbjct: 1523 AFEKIDELETKRKGLQNELDELANTQGTADKNVHELEKAKRALESQLAELKAQNEELEDD 1582
Query: 4654 LQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSG 4833
LQ+ EDA+LRLEV QAL+++ +R I K+ ++EEKRRGL+K +RDLE EL+ E++ ++
Sbjct: 1583 LQLTEDAKLRLEVNMQALRAQFERDIQAKEEQSEEKRRGLVKALRDLEAELDEERKQRAA 1642
Query: 4834 AVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAAL 5013
AV+ +KK+E + ++E LE+ N++KE+ + + EEA+ AKE++AA+
Sbjct: 1643 AVAAKKKLEGDLKDMEATLEMNNKVKEDALKQAKKLQAQIKDAIRDAEEAKAAKEELAAI 1702
Query: 5014 LREADRKFRAVEAEREQLRE---ANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRL 5184
+E++RK + +EA+ QL E ++E +A + + G + +EKRRL
Sbjct: 1703 SKESERKVKTLEADLMQLTEDLSSSERARRAAEGERDELLEEINSNSSKGSLMIDEKRRL 1762
Query: 5185 EAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSN 5364
EA+IA QSN EL +D+ RKAQ+ +EQ+TT+L+ E++ +Q E K LER N
Sbjct: 1763 EARIAALEEELEEEQSNLELMVDRNRKAQLTIEQLTTELATEKSNSQNNETLKCGLERLN 1822
Query: 5365 RDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDT 5544
++ KAK++E E+ +++ +A AA EAK LE QL E +E+ A +A R+LEKR+ +
Sbjct: 1823 KELKAKLSEQETALRTKLKAATAASEAKNLNLEKQLENETKERLAVQKANRKLEKRIKEL 1882
Query: 5545 TQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDAN 5724
T EDE+R +Q KE +EK+N + + L+R LDEAE+E+ +E+T R QRE +D+L+++
Sbjct: 1883 TMNIEDERRHADQYKEQIEKANNRMKTLKRNLDEAEEEIQKEKTLKRKAQRECEDMLESH 1942
Query: 5725 EQLTREL 5745
E L+RE+
Sbjct: 1943 EALSREV 1949
Score = 94.7 bits (234), Expect = 2e-17
Identities = 160/804 (19%), Positives = 288/804 (34%), Gaps = 128/804 (15%)
Frame = +1
Query: 2530 LQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSA 2709
L T E+R+K ++ AT ++ L E + +E L + + A + ++ EN
Sbjct: 1187 LDTTAAQQELRSKREQEVATLKKTL--EDESANHESTLMDMRHKHAQEISSINEQLEN-- 1242
Query: 2710 ELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXX 2889
L ++G L+ Q+LE D+ L RRKQ ET
Sbjct: 1243 -LKKMKGGLEKSKQQLEAENADLATELRNVNQSRQENDR-RRKQAETQIAELQVKLADVD 1300
Query: 2890 XXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKH 3069
DK Q + QLL+ E R K
Sbjct: 1301 RVRVELQDKVTKLQQESENITQQLDEAELKASAAIKSAGNLESQLTEAQQLLEEETRQKL 1360
Query: 3070 GVKAKGR-LENQLHELEQDLNRERQYKS----------------------------ELEQ 3162
+ +K R +E++ L++ L + + K+ ELE+
Sbjct: 1361 ALSSKLRQIESEKEALQEQLEEDEEAKTNYEKKLAELNFTIQEMKKRSEEDSDIAKELEE 1420
Query: 3163 HKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRD 3342
K+K+ ++E + + E + L+ K EL+ D + V ++K+ ++
Sbjct: 1421 SKKKMNKDIETLQRQIQELQAANDRLDKSKKKIQSELEDATIELDTQRTKVLELEKKQKN 1480
Query: 3343 MQTTIDE---LREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEA-TMLQDLMSR 3510
+ E + E + ER+A + + V L + + +K+DE T + L +
Sbjct: 1481 FDKVLAEEKAISEQVAQERDAAEREAREKETKVLSLTRELDEAFEKIDELETKRKGLQNE 1540
Query: 3511 KDEEVNATKRAIEQIQHTMEGK--IEEQKAKFSRQVEELHD--QIEQHKKQRSQLEKQQN 3678
DE N A + + + K +E Q A+ Q EEL D Q+ + K R ++ Q
Sbjct: 1541 LDELANTQGTADKNVHELEKAKRALESQLAELKAQNEELEDDLQLTEDAKLRLEVNMQAL 1600
Query: 3679 QADQERADMAQE----------IALLQASRADIDKKRKIH----------EAHLMEIQAN 3798
+A ER A+E + L+ A++D++RK E L +++A
Sbjct: 1601 RAQFERDIQAKEEQSEEKRRGLVKALRDLEAELDEERKQRAAAVAAKKKLEGDLKDMEAT 1660
Query: 3799 LAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANM-------QRRLATAXXXXXXX 3957
L +++ K + Q ++ + ++ R EE + A + +R++ T
Sbjct: 1661 LEMNNKVKEDALKQAKKLQAQIKDAIRDAEEAKAAKEELAAISKESERKVKTLEADLMQL 1720
Query: 3958 XXXXXXXTRLKIANINRARQLEDEKNA-------LLDEKEEAEGLRAHLEKEIHAARQGA 4116
R + A +L +E N+ ++DEK E A LE+E+ +
Sbjct: 1721 TEDLSSSERARRAAEGERDELLEEINSNSSKGSLMIDEKRRLEARIAALEEELEEEQSNL 1780
Query: 4117 G---EARRKAEESVNQQLEEL--RKKNLRDVE-----------HLQKQLEESEVA----- 4233
+ RKA+ ++ Q EL K N ++ E L+ +L E E A
Sbjct: 1781 ELMVDRNRKAQLTIEQLTTELATEKSNSQNNETLKCGLERLNKELKAKLSEQETALRTKL 1840
Query: 4234 ----------------------KERILQSK---------KKIQQELEDSSMELENVRASH 4320
KER+ K K++ +ED + +
Sbjct: 1841 KAATAASEAKNLNLEKQLENETKERLAVQKANRKLEKRIKELTMNIEDERRHADQYKEQI 1900
Query: 4321 RDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESD 4500
+ R K + + E +QK + +E D +L EV+ +K L
Sbjct: 1901 EKANNRMKTLKRNLDEAEEEIQKEKTLKRKAQRECEDMLESHEALSREVNALKSKLRRGG 1960
Query: 4501 RV-----RRSLQQELQDSISNKDD 4557
+ R + DSIS +D+
Sbjct: 1961 AMGSLSSTRLTPKRENDSISVQDE 1984
>gi|31198815|ref|XP_308355.1| ENSANGP00000009410 [Anopheles gambiae]
gi|30178670|gb|EAA45415.1| ENSANGP00000009410 [Anopheles gambiae str.
PEST]
Length = 2016
Score = 1866 bits (4833), Expect = 0.0
Identities = 962/1948 (49%), Positives = 1328/1948 (67%), Gaps = 35/1948 (1%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
+L+YL V+R + DPAT A W Q++L WVP +++GF+ SIK E DEV VEL +T ++V
Sbjct: 25 ELKYLSVERNSFNDPATQAEWTQKRLVWVPHESQGFVAASIKGERGDEVEVELAETGKRV 84
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
+ +DD+QK NPPKFDK+EDM+ELT LNEASVLHN+KDRYYS LIYTYSGLFCVV+NPYK
Sbjct: 85 LVLKDDIQKMNPPKFDKVEDMAELTCLNEASVLHNIKDRYYSGLIYTYSGLFCVVVNPYK 144
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
KLPIY+E ++E++KG KRHE+PPH+FAI DTAYRSMLQ+REDQSILCTGESGAGKTENTK
Sbjct: 145 KLPIYTEKIMEKYKGIKRHEVPPHVFAITDTAYRSMLQDREDQSILCTGESGAGKTENTK 204
Query: 547 KVIQYLAHVAGA-------------------TRNKSLNAA-----AQQNIVQKPDVRNPI 654
KVIQYLA+VA + +RNK + A ++ + +
Sbjct: 205 KVIQYLAYVAASKPKGSVAVGVGCSLYFPWRSRNKHVQPCIDCWEASNSLAEGLSALREM 264
Query: 655 ------GELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIEFYL 816
GELE QLLQANPILEAFGN+KTVKNDNSSRFGKFIRINFD SGYISGANIE YL
Sbjct: 265 RLLWGKGELEQQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDASGYISGANIETYL 324
Query: 817 LEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRFLVNRGITLPNVDDVQE 996
LEKSR +RQA+DER+FHIFYQ+L G S +++ ++L+ V Y FL N G+ +P VDD E
Sbjct: 325 LEKSRAIRQAKDERTFHIFYQLLAGASPEQRERFILDDVKTYPFLSNGGLPVPGVDDYAE 384
Query: 997 FHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLL 1176
F +T+ SM IMG ++ +SI R+VSAVLL G++ F QE+ SDQA L D+ V QK+ HLL
Sbjct: 385 FQATVKSMNIMGMTSEDFNSIFRIVSAVLLFGSMTFKQERNSDQATLPDNTVAQKIAHLL 444
Query: 1177 GLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRINKSLD 1356
GL V ++ KAFL PRIKVGR+FV KAQ +EQ EFAVEAIAKA YE++FKWLV RIN+SLD
Sbjct: 445 GLNVTDMTKAFLTPRIKVGRDFVTKAQTREQVEFAVEAIAKACYEKMFKWLVNRINRSLD 504
Query: 1357 RTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQREGIE 1536
RT RQGASFIGILD+AGFEIF++NSFEQ+CINYTNEKLQQLFN+TMFILEQEEYQREGIE
Sbjct: 505 RTKRQGASFIGILDMAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIE 564
Query: 1537 WDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTHNKHPKFIVPDM 1716
W FIDFGLDLQPTIDLI+KP G++ALLDEEC FPKA DKSFVEKL H+ HPKF+ D
Sbjct: 565 WKFIDFGLDLQPTIDLIDKPGGIMALLDEECWFPKATDKSFVEKLAAAHSMHPKFMKTDF 624
Query: 1717 RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGICA 1896
R + FAVVHYAG+VDYSA +WLMKNMDPLNENVV L+Q S DPFV IWKDAE G+
Sbjct: 625 RGVADFAVVHYAGKVDYSATKWLMKNMDPLNENVVSLLQASQDPFVVQIWKDAEIVGMAQ 684
Query: 1897 AEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSN 2076
+ +T FG R+RKGMFRTVS L+KEQL KLM TLRNT+P+FVRCIIPNHEK++GKI++
Sbjct: 685 QALTDTQFGARTRKGMFRTVSHLYKEQLAKLMDTLRNTNPNFVRCIIPNHEKRAGKIDAP 744
Query: 2077 LVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITA 2256
LVL+QLRCNGVLEGIRICRQGFPNR+PFQEFR RYE+LTP+VIPK F+DGK + +MI +
Sbjct: 745 LVLDQLRCNGVLEGIRICRQGFPNRIPFQEFRQRYELLTPNVIPKGFMDGKRACEQMIKS 804
Query: 2257 LDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXX 2436
L++D+NLYRIGQSK+FFR GVLAHLEEERD K+T LI+NFQA CRGFL+RR Y
Sbjct: 805 LELDSNLYRIGQSKIFFRAGVLAHLEEERDYKITDLIVNFQAFCRGFLARRNYQKRLQQL 864
Query: 2437 XXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEH 2616
N AYLKLRNWQWWRL+TKVKPLL+VT+ ++++ K+DELR +++L +
Sbjct: 865 NAIRIIQRNCAAYLKLRNWQWWRLYTKVKPLLEVTKQEEKLVQKEDELRQIRDKLENLSK 924
Query: 2617 DFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSX 2796
+ +E EKK Q + E+ + EQLQ E E AE ++ R RL R QELE ++ D+ R+
Sbjct: 925 NSQEYEKKYQQAMEEKTHLAEQLQAEIELCAEAEEGRARLVARKQELEELMQDLESRIEE 984
Query: 2797 XXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDA 2976
++K ++D +K +D +D
Sbjct: 985 EEERVNALTSEKKKLQINIQDLEEQLEEEEAARQKLQLEKVQLDAKLKKMEEDVALIEDQ 1044
Query: 2977 YDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSEL 3156
L+ L + EE+AKH K K + E+ + ELE+ L ++ Q + E
Sbjct: 1045 NHKLVKEKKLLEERANDLSQTLAEEEEKAKHLAKLKVKHESTIAELEERLLKDHQQRQEA 1104
Query: 3157 EQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQM 3336
++ KRK+ E+ D K+ + E+ ++EE+ QL+KR+EEL L R DEESA QK
Sbjct: 1105 DRSKRKIETEVADLKEQINERRMQIEEMQQQLVKREEELAQTLVRIDEESAAKAAAQKTQ 1164
Query: 3337 RDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKD 3516
R++++ + E++ED+E E+ AR+KAE +R++ +LE +K ++LD +D Q+L S+++
Sbjct: 1165 RELESQLAEIQEDLEAEKLARSKAEKQKRDLNEELEALKNELLDSLDTTAAQQELRSKRE 1224
Query: 3517 EEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQER 3696
+EV K+ +E E + + + K ++++ +++Q+E KK + LEK + Q + E
Sbjct: 1225 QEVATLKKTLEDESANHESTLMDMRHKHAQEISSINEQLENLKKMKGGLEKSKQQLEAEN 1284
Query: 3697 ADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLN 3876
AD+A E+ + SR + D++RK E + E+Q LA+ D + L D++ + + E +++
Sbjct: 1285 ADLATELRNVNQSRQENDRRRKQAETQIAELQVKLADVDRVRVELQDKVTKLQQESENIT 1344
Query: 3877 RVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKE 4056
+ +E E + + TR K+A ++ RQ+E EK AL ++ E
Sbjct: 1345 QQLDEAELKASAAIKSAGNLESQLTEAQQLLEEETRQKLALSSKLRQIESEKEALQEQLE 1404
Query: 4057 EAEGLRAHLEKEIHAARQGAGEARRKAEE--SVNQQLEELRKKNLRDVEHLQKQLEESEV 4230
E E + + EK++ E ++++EE + ++LEE +KK +D+E LQ+Q++E +
Sbjct: 1405 EDEEAKTNYEKKLAELNFTIQEMKKRSEEDSDIAKELEESKKKMNKDIETLQRQIQELQA 1464
Query: 4231 AKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDA 4410
A +R+ +SKKKIQ ELED+++EL+ R + EK+QK F+ +AEE+ ++ +RDA
Sbjct: 1465 ANDRLDKSKKKIQSELEDATIELDTQRTKVLELEKKQKNFDKVLAEEKAISEQVAQERDA 1524
Query: 4411 MSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKA 4590
+E R++ET+VLSL E+D E ++E + R+ LQ EL + + + KNVHELEKA
Sbjct: 1525 AEREAREKETKVLSLTRELDEAFEKIDELETKRKGLQNELDELANTQGTADKNVHELEKA 1584
Query: 4591 KRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRG 4770
KR+LE++L +++ Q EELED+LQ+ EDA+LRLEV QAL+++ +R I K+ ++EEKRRG
Sbjct: 1585 KRALESQLAELKAQNEELEDDLQLTEDAKLRLEVNMQALRAQFERDIQAKEEQSEEKRRG 1644
Query: 4771 LLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXX 4950
L+K +RDLE EL+ E++ ++ AV+ +KK+E + ++E LE+ N++KE+
Sbjct: 1645 LVKALRDLEAELDEERKQRAAAVAAKKKLEGDLKDMEATLEMNNKVKEDALKQAKKLQAQ 1704
Query: 4951 XXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLRE---ANEGLMQARKQXXXXX 5121
+ + EEA+ AKE++AA+ +E++RK + +EA+ QL E ++E +A +
Sbjct: 1705 IKDAIRDAEEAKAAKEELAAISKESERKVKTLEADLMQLTEDLSSSERARRAAEGERDEL 1764
Query: 5122 XXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDL 5301
+ G + +EKRRLEA+IA QSN EL +D+ RKAQ+ +EQ+TT+L
Sbjct: 1765 LEEINSNSSKGSLMIDEKRRLEARIAALEEELEEEQSNLELMVDRNRKAQLTIEQLTTEL 1824
Query: 5302 SMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVE 5481
+ E++ +Q E K LER N++ KAK++E E+ +++ +A AA EAK LE QL E
Sbjct: 1825 ATEKSNSQNNETLKCGLERLNKELKAKLSEQETALRTKLKAATAASEAKNLNLEKQLENE 1884
Query: 5482 GQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEM 5661
+E+ A +A R+LEKR+ + T EDE+R +Q KE +EK+N + + L+R LDEAE+E+
Sbjct: 1885 TKERLAVQKANRKLEKRIKELTMNIEDERRHADQYKEQIEKANNRMKTLKRNLDEAEEEI 1944
Query: 5662 SRERTKHRNVQREADDLLDANEQLTREL 5745
+E+T R QRE +D+L+++E L+RE+
Sbjct: 1945 QKEKTLKRKAQRECEDMLESHEALSREV 1972
Score = 94.7 bits (234), Expect = 2e-17
Identities = 160/804 (19%), Positives = 288/804 (34%), Gaps = 128/804 (15%)
Frame = +1
Query: 2530 LQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSA 2709
L T E+R+K ++ AT ++ L E + +E L + + A + ++ EN
Sbjct: 1210 LDTTAAQQELRSKREQEVATLKKTL--EDESANHESTLMDMRHKHAQEISSINEQLEN-- 1265
Query: 2710 ELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXX 2889
L ++G L+ Q+LE D+ L RRKQ ET
Sbjct: 1266 -LKKMKGGLEKSKQQLEAENADLATELRNVNQSRQENDR-RRKQAETQIAELQVKLADVD 1323
Query: 2890 XXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKH 3069
DK Q + QLL+ E R K
Sbjct: 1324 RVRVELQDKVTKLQQESENITQQLDEAELKASAAIKSAGNLESQLTEAQQLLEEETRQKL 1383
Query: 3070 GVKAKGR-LENQLHELEQDLNRERQYKS----------------------------ELEQ 3162
+ +K R +E++ L++ L + + K+ ELE+
Sbjct: 1384 ALSSKLRQIESEKEALQEQLEEDEEAKTNYEKKLAELNFTIQEMKKRSEEDSDIAKELEE 1443
Query: 3163 HKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRD 3342
K+K+ ++E + + E + L+ K EL+ D + V ++K+ ++
Sbjct: 1444 SKKKMNKDIETLQRQIQELQAANDRLDKSKKKIQSELEDATIELDTQRTKVLELEKKQKN 1503
Query: 3343 MQTTIDE---LREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEA-TMLQDLMSR 3510
+ E + E + ER+A + + V L + + +K+DE T + L +
Sbjct: 1504 FDKVLAEEKAISEQVAQERDAAEREAREKETKVLSLTRELDEAFEKIDELETKRKGLQNE 1563
Query: 3511 KDEEVNATKRAIEQIQHTMEGK--IEEQKAKFSRQVEELHD--QIEQHKKQRSQLEKQQN 3678
DE N A + + + K +E Q A+ Q EEL D Q+ + K R ++ Q
Sbjct: 1564 LDELANTQGTADKNVHELEKAKRALESQLAELKAQNEELEDDLQLTEDAKLRLEVNMQAL 1623
Query: 3679 QADQERADMAQE----------IALLQASRADIDKKRKIH----------EAHLMEIQAN 3798
+A ER A+E + L+ A++D++RK E L +++A
Sbjct: 1624 RAQFERDIQAKEEQSEEKRRGLVKALRDLEAELDEERKQRAAAVAAKKKLEGDLKDMEAT 1683
Query: 3799 LAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANM-------QRRLATAXXXXXXX 3957
L +++ K + Q ++ + ++ R EE + A + +R++ T
Sbjct: 1684 LEMNNKVKEDALKQAKKLQAQIKDAIRDAEEAKAAKEELAAISKESERKVKTLEADLMQL 1743
Query: 3958 XXXXXXXTRLKIANINRARQLEDEKNA-------LLDEKEEAEGLRAHLEKEIHAARQGA 4116
R + A +L +E N+ ++DEK E A LE+E+ +
Sbjct: 1744 TEDLSSSERARRAAEGERDELLEEINSNSSKGSLMIDEKRRLEARIAALEEELEEEQSNL 1803
Query: 4117 G---EARRKAEESVNQQLEEL--RKKNLRDVE-----------HLQKQLEESEVA----- 4233
+ RKA+ ++ Q EL K N ++ E L+ +L E E A
Sbjct: 1804 ELMVDRNRKAQLTIEQLTTELATEKSNSQNNETLKCGLERLNKELKAKLSEQETALRTKL 1863
Query: 4234 ----------------------KERILQSK---------KKIQQELEDSSMELENVRASH 4320
KER+ K K++ +ED + +
Sbjct: 1864 KAATAASEAKNLNLEKQLENETKERLAVQKANRKLEKRIKELTMNIEDERRHADQYKEQI 1923
Query: 4321 RDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESD 4500
+ R K + + E +QK + +E D +L EV+ +K L
Sbjct: 1924 EKANNRMKTLKRNLDEAEEEIQKEKTLKRKAQRECEDMLESHEALSREVNALKSKLRRGG 1983
Query: 4501 RV-----RRSLQQELQDSISNKDD 4557
+ R + DSIS +D+
Sbjct: 1984 AMGSLSSTRLTPKRENDSISVQDE 2007
>gi|24762816|ref|NP_523860.2| CG15792-PA [Drosophila melanogaster]
gi|7291892|gb|AAF47311.1| CG15792-PA [Drosophila melanogaster]
Length = 2056
Score = 1860 bits (4819), Expect = 0.0
Identities = 954/1949 (48%), Positives = 1332/1949 (67%), Gaps = 36/1949 (1%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
+L+YL V+R DPAT A W Q++L WVP +N+GF+ SIKRE DEV VEL +T ++V
Sbjct: 56 ELKYLSVERNQFNDPATQAEWTQKRLVWVPHENQGFVAASIKREHGDEVEVELAETGKRV 115
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
I RDD+QK NPPKFDK+EDM+ELT LNEASVLHN+KDRYYS LIYTYSGLFCVV+NPYK
Sbjct: 116 MILRDDIQKMNPPKFDKVEDMAELTCLNEASVLHNIKDRYYSGLIYTYSGLFCVVVNPYK 175
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
KLPIY+E ++E +KG KRHE+PPH+FAI D+AYR+ML +REDQSILCTGESGAGKTENTK
Sbjct: 176 KLPIYTEKIMERYKGIKRHEVPPHVFAITDSAYRNMLGDREDQSILCTGESGAGKTENTK 235
Query: 547 KVIQYLAHVAGATR-------------NKSLNA-------AAQQNIVQKPDVRNPI---- 654
KVIQ+LA+VA + N S+N QN Q +V N +
Sbjct: 236 KVIQFLAYVAASKPKGSGAVPHPAVLINFSVNTNKYIKVKIMAQNQNQTIEVVNGLKMVE 295
Query: 655 -------GELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIEFY 813
GELE QLLQANPILEAFGN+KTVKNDNSSRFGKFIRINFD SG+ISGANIE Y
Sbjct: 296 VNSNCQEGELEQQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDASGFISGANIETY 355
Query: 814 LLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRFLVNRGITLPNVDDVQ 993
LLEKSR +RQA+DER+FHIFYQ+L G + +++ +++L+ V +Y FL N + +P VDD
Sbjct: 356 LLEKSRAIRQAKDERTFHIFYQLLAGATPEQREKFILDDVKSYAFLSNGSLPVPGVDDYA 415
Query: 994 EFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQKVCHL 1173
EF +T+ SM IMG ++ +SI R+VSAVLL G+++F QE+ +DQA L D+ V QK+ HL
Sbjct: 416 EFQATVKSMNIMGMTSEDFNSIFRIVSAVLLFGSMKFRQERNNDQATLPDNTVAQKIAHL 475
Query: 1174 LGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRINKSL 1353
LGL V ++ +AFL PRIKVGR+FV KAQ +EQ EFAVEAIAKA YER+FKWLV RIN+SL
Sbjct: 476 LGLSVTDMTRAFLTPRIKVGRDFVTKAQTKEQVEFAVEAIAKACYERMFKWLVNRINRSL 535
Query: 1354 DRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQREGI 1533
DRT RQGASFIGILD+AGFEIF++NSFEQ+CINYTNEKLQQLFN+TMFILEQEEYQREGI
Sbjct: 536 DRTKRQGASFIGILDMAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGI 595
Query: 1534 EWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTHNKHPKFIVPD 1713
EW FIDFGLDLQPTIDLI+KP G++ALLDEEC FPKA DK+FV+KL H+ HPKF+ D
Sbjct: 596 EWKFIDFGLDLQPTIDLIDKPGGIMALLDEECWFPKATDKTFVDKLVSAHSMHPKFMKTD 655
Query: 1714 MRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGIC 1893
R + FA+VHYAGRVDYSA +WLMKNMDPLNEN+V L+Q S DPFV IWKDAE G+
Sbjct: 656 FRGVADFAIVHYAGRVDYSAAKWLMKNMDPLNENIVSLLQGSQDPFVVNIWKDAEIVGMA 715
Query: 1894 AAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINS 2073
+ +T FG R+RKGMFRTVS L+KEQL KLM TLRNT+P+FVRCIIPNHEK++GKI++
Sbjct: 716 QQALTDTQFGARTRKGMFRTVSHLYKEQLAKLMDTLRNTNPNFVRCIIPNHEKRAGKIDA 775
Query: 2074 NLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMIT 2253
LVL+QLRCNGVLEGIRICRQGFPNR+PFQEFR RYE+LTP+VIPK F+DGK++ KMI
Sbjct: 776 PLVLDQLRCNGVLEGIRICRQGFPNRIPFQEFRQRYELLTPNVIPKGFMDGKKACEKMIQ 835
Query: 2254 ALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXX 2433
AL++D+NLYR+GQSK+FFR GVLAHLEEERD K++ LI+NFQA CRGFL+RR Y
Sbjct: 836 ALELDSNLYRVGQSKIFFRAGVLAHLEEERDFKISDLIVNFQAFCRGFLARRNYQKRLQQ 895
Query: 2434 XXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKME 2613
N AYLKLRNWQWWRL+TKVKPLL+VT+ ++++ K+DEL+ +E+L +
Sbjct: 896 LNAIRIIQRNCAAYLKLRNWQWWRLYTKVKPLLEVTKQEEKLVQKEDELKQVREKLDTLA 955
Query: 2614 HDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLS 2793
+ +E E+K Q +VE+ + EQLQ E E AE ++ R RL R QELE ++ ++ R+
Sbjct: 956 KNTQEYERKYQQALVEKTTLAEQLQAEIELCAEAEESRSRLMARKQELEDMMQELETRIE 1015
Query: 2794 XXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQD 2973
++K ++D +K +D D
Sbjct: 1016 EEEERVLALGGEKKKLELNIQDLEEQLEEEEAARQKLQLEKVQLDAKIKKYEEDLALTDD 1075
Query: 2974 AYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSE 3153
L+ L + EE+AKH K K + E + ELE+ L++++Q + E
Sbjct: 1076 QNQKLLKEKKLLEERANDLSQTLAEEEEKAKHLAKLKAKHEATISELEERLHKDQQQRQE 1135
Query: 3154 LEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQ 3333
++ KRK+ E+ D K+ L E+ +V+E+ QL KR+EEL L R DEESA QK
Sbjct: 1136 SDRSKRKIETEVADLKEQLNERRVQVDEMQAQLAKREEELTQTLLRIDEESATKATAQKA 1195
Query: 3334 MRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRK 3513
R++++ + E++ED+E E+ AR KAE RR++ +LE +K ++LD +D Q+L S++
Sbjct: 1196 QRELESQLAEIQEDLEAEKAARAKAEKVRRDLSEELEALKNELLDSLDTTAAQQELRSKR 1255
Query: 3514 DEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQE 3693
++E+ K+++E+ EG + + + K S+++ ++DQ+E +K ++ LEK + + E
Sbjct: 1256 EQELATLKKSLEEETVNHEGVLADMRHKHSQELNSINDQLENLRKAKTVLEKAKGTLEAE 1315
Query: 3694 RADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHL 3873
AD+A E+ + +SR + D++RK E+ + E+Q LAE + + L ++ + + E +++
Sbjct: 1316 NADLATELRSVNSSRQENDRRRKQAESQIAELQVKLAEIERARSELQEKCTKLQQEAENI 1375
Query: 3874 NRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEK 4053
EE E + + + TR K+ ++ RQ+E EK AL ++
Sbjct: 1376 TNQLEEAELKASAAVKSASNMESQLTEAQQLLEEETRQKLGLSSKLRQIESEKEALQEQL 1435
Query: 4054 EEAEGLRAHLEKEIHAARQGAGEARRKAEESVN--QQLEELRKKNLRDVEHLQKQLEESE 4227
EE + + + E+++ E ++KAEE + ++LEE +K+ +D+E L++Q++E
Sbjct: 1436 EEDDEAKRNYERKLAEVTTQMQEIKKKAEEDADLAKELEEGKKRLNKDIEALERQVKELI 1495
Query: 4228 VAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRD 4407
+R+ +SKKKIQ ELED+++ELE R + EK+QK F+ +AEE+ ++ +RD
Sbjct: 1496 AQNDRLDKSKKKIQSELEDATIELEAQRTKVLELEKKQKNFDKILAEEKAISEQIAQERD 1555
Query: 4408 AMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEK 4587
+E R++ET+VLS+ E+D + +E+ + R++LQ EL D + + KNVHELEK
Sbjct: 1556 TAEREAREKETKVLSVSRELDEAFDKIEDLENKRKTLQNELDDLANTQGTADKNVHELEK 1615
Query: 4588 AKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRR 4767
AKR+LE++L +++ Q EELED+LQ+ EDA+LRLEV QAL+S+ +R + K+ AEEKRR
Sbjct: 1616 AKRALESQLAELKAQNEELEDDLQLTEDAKLRLEVNMQALRSQFERDLLAKEEGAEEKRR 1675
Query: 4768 GLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXX 4947
GL+KQ+RDLE EL+ E++ ++ AV+ +KK+E + E+E +E+ N++KE+
Sbjct: 1676 GLVKQLRDLETELDEERKQRTAAVASKKKLEGDLKEIETTMEMHNKVKEDALKHAKKLQA 1735
Query: 4948 XXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLRE---ANEGLMQARKQXXXX 5118
+ + EEA+ AKE++ AL +EA+RK +A+EAE QL E ++E +A +
Sbjct: 1736 QVKDALRDAEEAKAAKEELQALSKEAERKVKALEAEVLQLTEDLASSERARRAAETERDE 1795
Query: 5119 XXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTD 5298
A G + +EKRRLEA+IA QSN E+ +D+ RKAQ+Q+EQ+TT+
Sbjct: 1796 LAEEIANNANKGSLMIDEKRRLEARIATLEEELEEEQSNSEVLLDRSRKAQLQIEQLTTE 1855
Query: 5299 LSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNV 5478
L+ E++ +QK E + LER N++ KAK+ E+E+ +++ +A +A LEAK+ LE+QL
Sbjct: 1856 LANEKSNSQKNENGRALLERQNKELKAKLAEIETAQRTKVKATIATLEAKIANLEEQLEN 1915
Query: 5479 EGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDE 5658
EG+E+ +A R+++K++ + T EDE+R +Q KE ++K N + + L+R LDE E+E
Sbjct: 1916 EGKERLLQQKANRKMDKKIKELTMNIEDERRHVDQHKEQMDKLNSRIKLLKRNLDETEEE 1975
Query: 5659 MSRERTKHRNVQREADDLLDANEQLTREL 5745
+ +E+T+ R QRE +D++++ E + RE+
Sbjct: 1976 LQKEKTQKRKYQRECEDMIESQEAMNREI 2004
Score = 161 bits (407), Expect = 2e-37
Identities = 183/892 (20%), Positives = 374/892 (41%), Gaps = 55/892 (6%)
Frame = +1
Query: 2530 LQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSA 2709
+QV ++ +++EL T R+ + +K ++ + A IQE L+ E A
Sbjct: 1159 VQVDEMQAQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAEKAARA 1218
Query: 2710 ELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXX 2889
+ + +R L ++ELE + N++ D L R +++ T++
Sbjct: 1219 KAEKVRRDL---SEELEALKNELLDSLDTTAAQQELRSK-REQELATLKKSLEEETVNHE 1274
Query: 2890 XXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKH 3069
K + Q + A L T+L +
Sbjct: 1275 GVLADMRHKHS--QELNSINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQE 1332
Query: 3070 GVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQ 3249
+ + + E+Q+ EL+ L + +SEL++ KL E E+ + L E K
Sbjct: 1333 NDRRRKQAESQIAELQVKLAEIERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKS 1392
Query: 3250 LMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREV 3429
+ +L +EE+ + ++R +++ + L+E +E + A+ E EV
Sbjct: 1393 ASNMESQLTEAQQLLEEETRQKLGLSSKLRQIESEKEALQEQLEEDDEAKRNYERKLAEV 1452
Query: 3430 VAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQ 3609
Q++++K + D A L++ R ++++ A +R ++++ ++++ K K +
Sbjct: 1453 TTQMQEIKKKAEEDADLAKELEEGKKRLNKDIEALERQVKELI-AQNDRLDKSKKKIQSE 1511
Query: 3610 VEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEI 3789
+E+ ++E + + +LEK+Q D+ A+ + R +++ + E ++ +
Sbjct: 1512 LEDATIELEAQRTKVLELEKKQKNFDKILAEEKAISEQIAQERDTAEREAREKETKVLSV 1571
Query: 3790 QANLAESDEHKRTLIDQLERSRDELDHLNRVR---EEEEHAFANMQRRLATAXXXXXXXX 3960
L E+ + L ++ + ++ELD L + ++ H +R L +
Sbjct: 1572 SRELDEAFDKIEDLENKRKTLQNELDDLANTQGTADKNVHELEKAKRALESQLA------ 1625
Query: 3961 XXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAE 4140
LK N L+ ++A L + + LR+ E+++ A +GA E RR
Sbjct: 1626 -------ELKAQNEELEDDLQLTEDAKLRLEVNMQALRSQFERDLLAKEEGAEEKRRGLV 1678
Query: 4141 ESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASH 4320
K LRD+E +L+E + + SKKK++ +L++ +E
Sbjct: 1679 ------------KQLRDLE---TELDEERKQRTAAVASKKKLEGDLKEIETTMEMHNKVK 1723
Query: 4321 RDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESD 4500
D+ K KK ++Q+ + ++A ++ + ++ E +V +L EV + E L S+
Sbjct: 1724 EDALKHAKKLQAQVKDALRDAEEAKAAKEELQALSKEAERKVKALEAEVLQLTEDLASSE 1783
Query: 4501 RVRRSLQ---QELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAED 4671
R RR+ + EL + I+N + G + + KR LEA + + ++EE + N ++ D
Sbjct: 1784 RARRAAETERDELAEEIANNANKGSLMID---EKRRLEARIATLEEELEEEQSNSEVLLD 1840
Query: 4672 ----ARLRLEVTNQAL--------KSESDRAI---SNKDVEA-----EEKRRGLLK---- 4779
A+L++E L K+E+ RA+ NK+++A E +R +K
Sbjct: 1841 RSRKAQLQIEQLTTELANEKSNSQKNENGRALLERQNKELKAKLAEIETAQRTKVKATIA 1900
Query: 4780 ----QIRDLENELENEKRGKSGAVSHRKKIENQIGEL---------------EQQLEVAN 4902
+I +LE +LENE + + +K++ +I EL EQ ++ +
Sbjct: 1901 TLEAKIANLEEQLENEGKERLLQQKANRKMDKKIKELTMNIEDERRHVDQHKEQMDKLNS 1960
Query: 4903 RLK------EEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFR 5040
R+K +E +YQ ECE+ +++E + + K R
Sbjct: 1961 RIKLLKRNLDETEEELQKEKTQKRKYQRECEDMIESQEAMNREINSLKTKLR 2012
>gi|24762818|ref|NP_726506.1| CG15792-PB [Drosophila melanogaster]
gi|21645103|gb|AAM70805.1| CG15792-PB [Drosophila melanogaster]
Length = 2011
Score = 1860 bits (4819), Expect = 0.0
Identities = 954/1949 (48%), Positives = 1332/1949 (67%), Gaps = 36/1949 (1%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
+L+YL V+R DPAT A W Q++L WVP +N+GF+ SIKRE DEV VEL +T ++V
Sbjct: 11 ELKYLSVERNQFNDPATQAEWTQKRLVWVPHENQGFVAASIKREHGDEVEVELAETGKRV 70
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
I RDD+QK NPPKFDK+EDM+ELT LNEASVLHN+KDRYYS LIYTYSGLFCVV+NPYK
Sbjct: 71 MILRDDIQKMNPPKFDKVEDMAELTCLNEASVLHNIKDRYYSGLIYTYSGLFCVVVNPYK 130
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
KLPIY+E ++E +KG KRHE+PPH+FAI D+AYR+ML +REDQSILCTGESGAGKTENTK
Sbjct: 131 KLPIYTEKIMERYKGIKRHEVPPHVFAITDSAYRNMLGDREDQSILCTGESGAGKTENTK 190
Query: 547 KVIQYLAHVAGATR-------------NKSLNA-------AAQQNIVQKPDVRNPI---- 654
KVIQ+LA+VA + N S+N QN Q +V N +
Sbjct: 191 KVIQFLAYVAASKPKGSGAVPHPAVLINFSVNTNKYIKVKIMAQNQNQTIEVVNGLKMVE 250
Query: 655 -------GELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIEFY 813
GELE QLLQANPILEAFGN+KTVKNDNSSRFGKFIRINFD SG+ISGANIE Y
Sbjct: 251 VNSNCQEGELEQQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDASGFISGANIETY 310
Query: 814 LLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRFLVNRGITLPNVDDVQ 993
LLEKSR +RQA+DER+FHIFYQ+L G + +++ +++L+ V +Y FL N + +P VDD
Sbjct: 311 LLEKSRAIRQAKDERTFHIFYQLLAGATPEQREKFILDDVKSYAFLSNGSLPVPGVDDYA 370
Query: 994 EFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQKVCHL 1173
EF +T+ SM IMG ++ +SI R+VSAVLL G+++F QE+ +DQA L D+ V QK+ HL
Sbjct: 371 EFQATVKSMNIMGMTSEDFNSIFRIVSAVLLFGSMKFRQERNNDQATLPDNTVAQKIAHL 430
Query: 1174 LGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRINKSL 1353
LGL V ++ +AFL PRIKVGR+FV KAQ +EQ EFAVEAIAKA YER+FKWLV RIN+SL
Sbjct: 431 LGLSVTDMTRAFLTPRIKVGRDFVTKAQTKEQVEFAVEAIAKACYERMFKWLVNRINRSL 490
Query: 1354 DRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQREGI 1533
DRT RQGASFIGILD+AGFEIF++NSFEQ+CINYTNEKLQQLFN+TMFILEQEEYQREGI
Sbjct: 491 DRTKRQGASFIGILDMAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGI 550
Query: 1534 EWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTHNKHPKFIVPD 1713
EW FIDFGLDLQPTIDLI+KP G++ALLDEEC FPKA DK+FV+KL H+ HPKF+ D
Sbjct: 551 EWKFIDFGLDLQPTIDLIDKPGGIMALLDEECWFPKATDKTFVDKLVSAHSMHPKFMKTD 610
Query: 1714 MRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGIC 1893
R + FA+VHYAGRVDYSA +WLMKNMDPLNEN+V L+Q S DPFV IWKDAE G+
Sbjct: 611 FRGVADFAIVHYAGRVDYSAAKWLMKNMDPLNENIVSLLQGSQDPFVVNIWKDAEIVGMA 670
Query: 1894 AAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINS 2073
+ +T FG R+RKGMFRTVS L+KEQL KLM TLRNT+P+FVRCIIPNHEK++GKI++
Sbjct: 671 QQALTDTQFGARTRKGMFRTVSHLYKEQLAKLMDTLRNTNPNFVRCIIPNHEKRAGKIDA 730
Query: 2074 NLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMIT 2253
LVL+QLRCNGVLEGIRICRQGFPNR+PFQEFR RYE+LTP+VIPK F+DGK++ KMI
Sbjct: 731 PLVLDQLRCNGVLEGIRICRQGFPNRIPFQEFRQRYELLTPNVIPKGFMDGKKACEKMIQ 790
Query: 2254 ALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXX 2433
AL++D+NLYR+GQSK+FFR GVLAHLEEERD K++ LI+NFQA CRGFL+RR Y
Sbjct: 791 ALELDSNLYRVGQSKIFFRAGVLAHLEEERDFKISDLIVNFQAFCRGFLARRNYQKRLQQ 850
Query: 2434 XXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKME 2613
N AYLKLRNWQWWRL+TKVKPLL+VT+ ++++ K+DEL+ +E+L +
Sbjct: 851 LNAIRIIQRNCAAYLKLRNWQWWRLYTKVKPLLEVTKQEEKLVQKEDELKQVREKLDTLA 910
Query: 2614 HDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLS 2793
+ +E E+K Q +VE+ + EQLQ E E AE ++ R RL R QELE ++ ++ R+
Sbjct: 911 KNTQEYERKYQQALVEKTTLAEQLQAEIELCAEAEESRSRLMARKQELEDMMQELETRIE 970
Query: 2794 XXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQD 2973
++K ++D +K +D D
Sbjct: 971 EEEERVLALGGEKKKLELNIQDLEEQLEEEEAARQKLQLEKVQLDAKIKKYEEDLALTDD 1030
Query: 2974 AYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSE 3153
L+ L + EE+AKH K K + E + ELE+ L++++Q + E
Sbjct: 1031 QNQKLLKEKKLLEERANDLSQTLAEEEEKAKHLAKLKAKHEATISELEERLHKDQQQRQE 1090
Query: 3154 LEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQ 3333
++ KRK+ E+ D K+ L E+ +V+E+ QL KR+EEL L R DEESA QK
Sbjct: 1091 SDRSKRKIETEVADLKEQLNERRVQVDEMQAQLAKREEELTQTLLRIDEESATKATAQKA 1150
Query: 3334 MRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRK 3513
R++++ + E++ED+E E+ AR KAE RR++ +LE +K ++LD +D Q+L S++
Sbjct: 1151 QRELESQLAEIQEDLEAEKAARAKAEKVRRDLSEELEALKNELLDSLDTTAAQQELRSKR 1210
Query: 3514 DEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQE 3693
++E+ K+++E+ EG + + + K S+++ ++DQ+E +K ++ LEK + + E
Sbjct: 1211 EQELATLKKSLEEETVNHEGVLADMRHKHSQELNSINDQLENLRKAKTVLEKAKGTLEAE 1270
Query: 3694 RADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHL 3873
AD+A E+ + +SR + D++RK E+ + E+Q LAE + + L ++ + + E +++
Sbjct: 1271 NADLATELRSVNSSRQENDRRRKQAESQIAELQVKLAEIERARSELQEKCTKLQQEAENI 1330
Query: 3874 NRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEK 4053
EE E + + + TR K+ ++ RQ+E EK AL ++
Sbjct: 1331 TNQLEEAELKASAAVKSASNMESQLTEAQQLLEEETRQKLGLSSKLRQIESEKEALQEQL 1390
Query: 4054 EEAEGLRAHLEKEIHAARQGAGEARRKAEESVN--QQLEELRKKNLRDVEHLQKQLEESE 4227
EE + + + E+++ E ++KAEE + ++LEE +K+ +D+E L++Q++E
Sbjct: 1391 EEDDEAKRNYERKLAEVTTQMQEIKKKAEEDADLAKELEEGKKRLNKDIEALERQVKELI 1450
Query: 4228 VAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRD 4407
+R+ +SKKKIQ ELED+++ELE R + EK+QK F+ +AEE+ ++ +RD
Sbjct: 1451 AQNDRLDKSKKKIQSELEDATIELEAQRTKVLELEKKQKNFDKILAEEKAISEQIAQERD 1510
Query: 4408 AMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEK 4587
+E R++ET+VLS+ E+D + +E+ + R++LQ EL D + + KNVHELEK
Sbjct: 1511 TAEREAREKETKVLSVSRELDEAFDKIEDLENKRKTLQNELDDLANTQGTADKNVHELEK 1570
Query: 4588 AKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRR 4767
AKR+LE++L +++ Q EELED+LQ+ EDA+LRLEV QAL+S+ +R + K+ AEEKRR
Sbjct: 1571 AKRALESQLAELKAQNEELEDDLQLTEDAKLRLEVNMQALRSQFERDLLAKEEGAEEKRR 1630
Query: 4768 GLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXX 4947
GL+KQ+RDLE EL+ E++ ++ AV+ +KK+E + E+E +E+ N++KE+
Sbjct: 1631 GLVKQLRDLETELDEERKQRTAAVASKKKLEGDLKEIETTMEMHNKVKEDALKHAKKLQA 1690
Query: 4948 XXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLRE---ANEGLMQARKQXXXX 5118
+ + EEA+ AKE++ AL +EA+RK +A+EAE QL E ++E +A +
Sbjct: 1691 QVKDALRDAEEAKAAKEELQALSKEAERKVKALEAEVLQLTEDLASSERARRAAETERDE 1750
Query: 5119 XXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTD 5298
A G + +EKRRLEA+IA QSN E+ +D+ RKAQ+Q+EQ+TT+
Sbjct: 1751 LAEEIANNANKGSLMIDEKRRLEARIATLEEELEEEQSNSEVLLDRSRKAQLQIEQLTTE 1810
Query: 5299 LSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNV 5478
L+ E++ +QK E + LER N++ KAK+ E+E+ +++ +A +A LEAK+ LE+QL
Sbjct: 1811 LANEKSNSQKNENGRALLERQNKELKAKLAEIETAQRTKVKATIATLEAKIANLEEQLEN 1870
Query: 5479 EGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDE 5658
EG+E+ +A R+++K++ + T EDE+R +Q KE ++K N + + L+R LDE E+E
Sbjct: 1871 EGKERLLQQKANRKMDKKIKELTMNIEDERRHVDQHKEQMDKLNSRIKLLKRNLDETEEE 1930
Query: 5659 MSRERTKHRNVQREADDLLDANEQLTREL 5745
+ +E+T+ R QRE +D++++ E + RE+
Sbjct: 1931 LQKEKTQKRKYQRECEDMIESQEAMNREI 1959
Score = 161 bits (407), Expect = 2e-37
Identities = 183/892 (20%), Positives = 374/892 (41%), Gaps = 55/892 (6%)
Frame = +1
Query: 2530 LQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSA 2709
+QV ++ +++EL T R+ + +K ++ + A IQE L+ E A
Sbjct: 1114 VQVDEMQAQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAEKAARA 1173
Query: 2710 ELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXX 2889
+ + +R L ++ELE + N++ D L R +++ T++
Sbjct: 1174 KAEKVRRDL---SEELEALKNELLDSLDTTAAQQELRSK-REQELATLKKSLEEETVNHE 1229
Query: 2890 XXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKH 3069
K + Q + A L T+L +
Sbjct: 1230 GVLADMRHKHS--QELNSINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQE 1287
Query: 3070 GVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQ 3249
+ + + E+Q+ EL+ L + +SEL++ KL E E+ + L E K
Sbjct: 1288 NDRRRKQAESQIAELQVKLAEIERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKS 1347
Query: 3250 LMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREV 3429
+ +L +EE+ + ++R +++ + L+E +E + A+ E EV
Sbjct: 1348 ASNMESQLTEAQQLLEEETRQKLGLSSKLRQIESEKEALQEQLEEDDEAKRNYERKLAEV 1407
Query: 3430 VAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQ 3609
Q++++K + D A L++ R ++++ A +R ++++ ++++ K K +
Sbjct: 1408 TTQMQEIKKKAEEDADLAKELEEGKKRLNKDIEALERQVKELI-AQNDRLDKSKKKIQSE 1466
Query: 3610 VEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEI 3789
+E+ ++E + + +LEK+Q D+ A+ + R +++ + E ++ +
Sbjct: 1467 LEDATIELEAQRTKVLELEKKQKNFDKILAEEKAISEQIAQERDTAEREAREKETKVLSV 1526
Query: 3790 QANLAESDEHKRTLIDQLERSRDELDHLNRVR---EEEEHAFANMQRRLATAXXXXXXXX 3960
L E+ + L ++ + ++ELD L + ++ H +R L +
Sbjct: 1527 SRELDEAFDKIEDLENKRKTLQNELDDLANTQGTADKNVHELEKAKRALESQLA------ 1580
Query: 3961 XXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAE 4140
LK N L+ ++A L + + LR+ E+++ A +GA E RR
Sbjct: 1581 -------ELKAQNEELEDDLQLTEDAKLRLEVNMQALRSQFERDLLAKEEGAEEKRRGLV 1633
Query: 4141 ESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASH 4320
K LRD+E +L+E + + SKKK++ +L++ +E
Sbjct: 1634 ------------KQLRDLE---TELDEERKQRTAAVASKKKLEGDLKEIETTMEMHNKVK 1678
Query: 4321 RDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESD 4500
D+ K KK ++Q+ + ++A ++ + ++ E +V +L EV + E L S+
Sbjct: 1679 EDALKHAKKLQAQVKDALRDAEEAKAAKEELQALSKEAERKVKALEAEVLQLTEDLASSE 1738
Query: 4501 RVRRSLQ---QELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAED 4671
R RR+ + EL + I+N + G + + KR LEA + + ++EE + N ++ D
Sbjct: 1739 RARRAAETERDELAEEIANNANKGSLMID---EKRRLEARIATLEEELEEEQSNSEVLLD 1795
Query: 4672 ----ARLRLEVTNQAL--------KSESDRAI---SNKDVEA-----EEKRRGLLK---- 4779
A+L++E L K+E+ RA+ NK+++A E +R +K
Sbjct: 1796 RSRKAQLQIEQLTTELANEKSNSQKNENGRALLERQNKELKAKLAEIETAQRTKVKATIA 1855
Query: 4780 ----QIRDLENELENEKRGKSGAVSHRKKIENQIGEL---------------EQQLEVAN 4902
+I +LE +LENE + + +K++ +I EL EQ ++ +
Sbjct: 1856 TLEAKIANLEEQLENEGKERLLQQKANRKMDKKIKELTMNIEDERRHVDQHKEQMDKLNS 1915
Query: 4903 RLK------EEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFR 5040
R+K +E +YQ ECE+ +++E + + K R
Sbjct: 1916 RIKLLKRNLDETEEELQKEKTQKRKYQRECEDMIESQEAMNREINSLKTKLR 1967
>gi|1141790|gb|AAB09051.1| nonmuscle myosin-II heavy chain [Drosophila
melanogaster]
Length = 1972
Score = 1844 bits (4777), Expect = 0.0
Identities = 944/1919 (49%), Positives = 1319/1919 (68%), Gaps = 6/1919 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRK-LCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQ 183
+L+YL V+R R L WVP +N+GF+ SIKRE DEV VEL +T ++
Sbjct: 11 ELKYLSVERNQFNPIRPRRPSGHRSVLVWVPHENQGFVAASIKREHGDEVEVELAETGKR 70
Query: 184 VTISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPY 363
V I RDD+QK NPPKFDK+EDM+ELT LNEASVLHN+KDRYYS LIYTYSGLFCVV+NPY
Sbjct: 71 VMILRDDIQKMNPPKFDKVEDMAELTCLNEASVLHNIKDRYYSGLIYTYSGLFCVVVNPY 130
Query: 364 KKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENT 543
KKLPIY+E ++E +KG KRHE+PPH+FAI D+AYR+ML +REDQSILCTGESGAGKTENT
Sbjct: 131 KKLPIYTEKIMERYKGIKRHEVPPHVFAITDSAYRNMLGDREDQSILCTGESGAGKTENT 190
Query: 544 KKVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTV 723
KKVIQ+LA+VA A++ K A ++ IGELE QLLQANPILEAFGN+KTV
Sbjct: 191 KKVIQFLAYVA-ASKPKGSGAVPHPAVL--------IGELEQQLLQANPILEAFGNAKTV 241
Query: 724 KNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAK 903
KNDNSSRFGKFIRINFD SG+ISGANIE YLLEKSR +RQA+DER+FHIFYQ+L G + +
Sbjct: 242 KNDNSSRFGKFIRINFDASGFISGANIETYLLEKSRAIRQAKDERTFHIFYQLLAGATPE 301
Query: 904 EKSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVL 1083
++ +++L+ V +Y FL N + +P VDD EF +T+ SM IMG ++ +SI R+VSAVL
Sbjct: 302 QREKFILDDVKSYAFLSNGSLPVPGVDDYAEFQATVKSMNIMGMTSEDFNSIFRIVSAVL 361
Query: 1084 LLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQ 1263
L G+++F QE+ +DQA L D+ V QK+ HLLGL V ++ +AFL PRIKVGR+FV KAQ +
Sbjct: 362 LFGSMKFRQERNNDQATLPDNTVAQKIAHLLGLSVTDMTRAFLTPRIKVGRDFVTKAQTK 421
Query: 1264 EQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQI 1443
EQ EFAVEAIAKA YER+FKWLV RIN+SLDRT RQGASFIGILD+AGFEIF++NSFEQ+
Sbjct: 422 EQVEFAVEAIAKACYERMFKWLVNRINRSLDRTKRQGASFIGILDMAGFEIFELNSFEQL 481
Query: 1444 CINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDE 1623
CINYTNEKLQQLFN+TMFILEQEEYQREGIEW FIDFGLDLQPTIDLI+KP G++ALLDE
Sbjct: 482 CINYTNEKLQQLFNHTMFILEQEEYQREGIEWKFIDFGLDLQPTIDLIDKPGGIMALLDE 541
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMDP 1803
EC FPKA DK+FV+KL H+ HPKF+ D R + FA+VHYAGRVDYSA +WLMKNMDP
Sbjct: 542 ECWFPKATDKTFVDKLVSAHSMHPKFMKTDFRGVADFAIVHYAGRVDYSAAKWLMKNMDP 601
Query: 1804 LNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLT 1983
LNEN+V L+Q S DPFV IWKDAE G+ + +T FG R+RKGMFRTVS L+KEQL
Sbjct: 602 LNENIVSLLQGSQDPFVVNIWKDAEIVGMAQQALTDTQFGARTRKGMFRTVSHLYKEQLA 661
Query: 1984 KLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQ 2163
KLM TLRNT+P+FVRCIIPNHEK++GKI++ LVL+QLRCNGVLEGIRICRQGFPNR+PFQ
Sbjct: 662 KLMDTLRNTNPNFVRCIIPNHEKRAGKIDAPLVLDQLRCNGVLEGIRICRQGFPNRIPFQ 721
Query: 2164 EFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEER 2343
EFR RYE+LTP+VIPK F+DGK++ KMI AL++D+NLYR+GQSK+FFR GVLAHLEEER
Sbjct: 722 EFRQRYELLTPNVIPKGFMDGKKACEKMIQALELDSNLYRVGQSKIFFRAGVLAHLEEER 781
Query: 2344 DLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVK 2523
D K++ LI+NFQA CRGFL+RR Y N AYLKLRNWQWWRL+TKVK
Sbjct: 782 DFKISDLIVNFQAFCRGFLARRNYQKRLQQLNAIRIIQRNCAAYLKLRNWQWWRLYTKVK 841
Query: 2524 PLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESEN 2703
PLL+VT+ ++++ K+DEL+ +E+L + + +E E+K Q +VE+ + EQLQ E E
Sbjct: 842 PLLEVTKQEEKLVQKEDELKQVREKLDTLAKNTQEYERKYQQALVEKTTLAEQLQAEIEL 901
Query: 2704 SAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXX 2883
AE ++ R RL R QELE ++ ++ R+ ++K ++D
Sbjct: 902 CAEAEESRSRLMARKQELEDMMQELETRIEEEEERVLALGGEKKKLELNIQDLEEQLEEE 961
Query: 2884 XXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERA 3063
+K +D D L+ L + EE+A
Sbjct: 962 EAARQKLQLEKVQLDAKIKKYEEDLALTDDQNQKLLKEKKLLEERANDLSQTLAEEEEKA 1021
Query: 3064 KHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELN 3243
KH K K + E + ELE+ L++++Q + E ++ KRK+ E+ D K+ L E+ +V+E+
Sbjct: 1022 KHLAKLKAKHEATITELEERLHKDQQQRQESDRSKRKIETEVADLKEQLNERRVQVDEMQ 1081
Query: 3244 NQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRR 3423
QL KR+EEL L R DEESA QK R++++ + E++ED+E E+ AR KAE RR
Sbjct: 1082 AQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAEKAARAKAEKVRR 1141
Query: 3424 EVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFS 3603
++ +LE +K ++LD +D Q+L S++++E+ K+++E+ EG + + + K S
Sbjct: 1142 DLSEELEALKNELLDSLDTTAAQQELRSKREQELATLKKSLEEETVNHEGVLADMRHKHS 1201
Query: 3604 RQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLM 3783
+++ ++DQ+E +K ++ LEK + + E AD+A E+ + +SR + D++RK E+ +
Sbjct: 1202 QELNSINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQENDRRRKQAESQIA 1261
Query: 3784 EIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXX 3963
E+Q LAE + + L ++ + + E +++ EE E + + +
Sbjct: 1262 ELQVKLAEIERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKSASNMESQLTEAQQ 1321
Query: 3964 XXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEE 4143
TR K+ ++ RQ+E EK AL ++ EE + + + E+++ E ++KAEE
Sbjct: 1322 LLEEETRQKLGLSSKLRQIESEKEALQEQLEEDDEAKRNYERKLAEVTTQMQEIKKKAEE 1381
Query: 4144 SVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRAS 4317
+ ++LEE +K+ +D+E L++Q++E +R+ +SKKKIQ ELED+++ELE R
Sbjct: 1382 DADLAKELEEGKKRLNKDIEALERQVKELIAQNDRLDKSKKKIQSELEDATIELEAQRTK 1441
Query: 4318 HRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEES 4497
+ EK+QK F+ +AEE+ ++ +RD +E R++ET+VLS+ E+D + +E+
Sbjct: 1442 VLELEKKQKNFDKILAEEKAISEQIAQERDTAEREAREKETKVLSVSRELDEAFDKIEDL 1501
Query: 4498 DRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDAR 4677
+ R++LQ EL D + + KNVHELEKAKR+LE++L +++ Q EELED+LQ+ EDA+
Sbjct: 1502 ENKRKTLQNELDDLANTQGTADKNVHELEKAKRALESQLAELKAQNEELEDDLQLTEDAK 1561
Query: 4678 LRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKI 4857
LRLEV QAL+S+ +R + K+ AEEKRRGL+KQ+RDLE EL+ E++ ++ AV+ +KK+
Sbjct: 1562 LRLEVNMQALRSQFERDLLAKEEGAEEKRRGLVKQLRDLETELDEERKQRTAAVASKKKL 1621
Query: 4858 ENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKF 5037
E + E+E +E+ N++KE+ + + EEA+ AKE++ AL +EAD K
Sbjct: 1622 EGDLKEIETTMEMHNKVKEDALKHAKKLQAQVKDALRDAEEAKAAKEELQALSKEADGKV 1681
Query: 5038 RAVEAEREQLRE---ANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXX 5208
+A+EAE QL E ++E +A + A G + +EKRRLEA+IA
Sbjct: 1682 KALEAEVLQLTEDLASSERARRAAETERDELAEEIANNANKGSLMIDEKRRLEARIATLE 1741
Query: 5209 XXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKIT 5388
QSN E+ +D+ RKAQ+Q+EQ+TT+L+ E++ +QK E + LER N++ KAK+
Sbjct: 1742 EELEEEQSNSEVLLDRSRKAQLQIEQLTTELANEKSNSQKNENGRALLERQNKELKAKLA 1801
Query: 5389 ELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEK 5568
E+E+ +++ +A +A LEAK+ LE+QL EG+E+ +A R+++K++ + T EDE+
Sbjct: 1802 EIETAQRTKVKATIATLEAKIANLEEQLENEGKERLLQQKANRKMDKKIKELTMNIEDER 1861
Query: 5569 RANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
R +Q KE ++K N + + L+R LDE E+E+ +E+T+ R QRE +D++++ E + RE+
Sbjct: 1862 RHVDQHKEQMDKLNSRIKLLKRNLDETEEELQKEKTQKRKYQRECEDMIESQEAMNREI 1920
Score = 160 bits (405), Expect = 3e-37
Identities = 192/935 (20%), Positives = 386/935 (40%), Gaps = 55/935 (5%)
Frame = +1
Query: 2530 LQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSA 2709
+QV ++ +++EL T R+ + +K ++ + A IQE L+ E A
Sbjct: 1075 VQVDEMQAQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAEKAARA 1134
Query: 2710 ELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXX 2889
+ + +R L ++ELE + N++ D L R +++ T++
Sbjct: 1135 KAEKVRRDL---SEELEALKNELLDSLDTTAAQQELRSK-REQELATLKKSLEEETVNHE 1190
Query: 2890 XXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKH 3069
K + Q + A L T+L +
Sbjct: 1191 GVLADMRHKHS--QELNSINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQE 1248
Query: 3070 GVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQ 3249
+ + + E+Q+ EL+ L + +SEL++ KL E E+ + L E K
Sbjct: 1249 NDRRRKQAESQIAELQVKLAEIERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKS 1308
Query: 3250 LMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREV 3429
+ +L +EE+ + ++R +++ + L+E +E + A+ E EV
Sbjct: 1309 ASNMESQLTEAQQLLEEETRQKLGLSSKLRQIESEKEALQEQLEEDDEAKRNYERKLAEV 1368
Query: 3430 VAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQ 3609
Q++++K + D A L++ R ++++ A +R ++++ ++++ K K +
Sbjct: 1369 TTQMQEIKKKAEEDADLAKELEEGKKRLNKDIEALERQVKELI-AQNDRLDKSKKKIQSE 1427
Query: 3610 VEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEI 3789
+E+ ++E + + +LEK+Q D+ A+ + R +++ + E ++ +
Sbjct: 1428 LEDATIELEAQRTKVLELEKKQKNFDKILAEEKAISEQIAQERDTAEREAREKETKVLSV 1487
Query: 3790 QANLAESDEHKRTLIDQLERSRDELDHLNRVR---EEEEHAFANMQRRLATAXXXXXXXX 3960
L E+ + L ++ + ++ELD L + ++ H +R L +
Sbjct: 1488 SRELDEAFDKIEDLENKRKTLQNELDDLANTQGTADKNVHELEKAKRALESQLA------ 1541
Query: 3961 XXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAE 4140
LK N L+ ++A L + + LR+ E+++ A +GA E RR
Sbjct: 1542 -------ELKAQNEELEDDLQLTEDAKLRLEVNMQALRSQFERDLLAKEEGAEEKRRGLV 1594
Query: 4141 ESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASH 4320
K LRD+E +L+E + + SKKK++ +L++ +E
Sbjct: 1595 ------------KQLRDLE---TELDEERKQRTAAVASKKKLEGDLKEIETTMEMHNKVK 1639
Query: 4321 RDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESD 4500
D+ K KK ++Q+ + ++A ++ + ++ + +V +L EV + E L S+
Sbjct: 1640 EDALKHAKKLQAQVKDALRDAEEAKAAKEELQALSKEADGKVKALEAEVLQLTEDLASSE 1699
Query: 4501 RVRRSLQ---QELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAED 4671
R RR+ + EL + I+N + G + + KR LEA + + ++EE + N ++ D
Sbjct: 1700 RARRAAETERDELAEEIANNANKGSLMID---EKRRLEARIATLEEELEEEQSNSEVLLD 1756
Query: 4672 ----ARLRLEVTNQAL--------KSESDRAI---SNKDVEA-----EEKRRGLLK---- 4779
A+L++E L K+E+ RA+ NK+++A E +R +K
Sbjct: 1757 RSRKAQLQIEQLTTELANEKSNSQKNENGRALLERQNKELKAKLAEIETAQRTKVKATIA 1816
Query: 4780 ----QIRDLENELENEKRGKSGAVSHRKKIENQIGEL---------------EQQLEVAN 4902
+I +LE +LENE + + +K++ +I EL EQ ++ +
Sbjct: 1817 TLEAKIANLEEQLENEGKERLLQQKANRKMDKKIKELTMNIEDERRHVDQHKEQMDKLNS 1876
Query: 4903 RLK------EEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQ 5064
R+K +E +YQ ECE+ +++E + + K R
Sbjct: 1877 RIKLLKRNLDETEEELQKEKTQKRKYQRECEDMIESQEAMNREINSLKTKLR-------- 1928
Query: 5065 LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSE 5169
R GL +R RA GGG S +
Sbjct: 1929 -RTGGIGLSSSR-----LTGTPSSKRAGGGGGSDD 1957
>gi|1572480|gb|AAB09048.1| nonmuscle myosin-II heavy chain [Drosophila
melanogaster]
Length = 2017
Score = 1844 bits (4777), Expect = 0.0
Identities = 944/1919 (49%), Positives = 1319/1919 (68%), Gaps = 6/1919 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRK-LCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQ 183
+L+YL V+R R L WVP +N+GF+ SIKRE DEV VEL +T ++
Sbjct: 56 ELKYLSVERNQFNPIRPRRPSGHRSVLVWVPHENQGFVAASIKREHGDEVEVELAETGKR 115
Query: 184 VTISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPY 363
V I RDD+QK NPPKFDK+EDM+ELT LNEASVLHN+KDRYYS LIYTYSGLFCVV+NPY
Sbjct: 116 VMILRDDIQKMNPPKFDKVEDMAELTCLNEASVLHNIKDRYYSGLIYTYSGLFCVVVNPY 175
Query: 364 KKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENT 543
KKLPIY+E ++E +KG KRHE+PPH+FAI D+AYR+ML +REDQSILCTGESGAGKTENT
Sbjct: 176 KKLPIYTEKIMERYKGIKRHEVPPHVFAITDSAYRNMLGDREDQSILCTGESGAGKTENT 235
Query: 544 KKVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTV 723
KKVIQ+LA+VA A++ K A ++ IGELE QLLQANPILEAFGN+KTV
Sbjct: 236 KKVIQFLAYVA-ASKPKGSGAVPHPAVL--------IGELEQQLLQANPILEAFGNAKTV 286
Query: 724 KNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAK 903
KNDNSSRFGKFIRINFD SG+ISGANIE YLLEKSR +RQA+DER+FHIFYQ+L G + +
Sbjct: 287 KNDNSSRFGKFIRINFDASGFISGANIETYLLEKSRAIRQAKDERTFHIFYQLLAGATPE 346
Query: 904 EKSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVL 1083
++ +++L+ V +Y FL N + +P VDD EF +T+ SM IMG ++ +SI R+VSAVL
Sbjct: 347 QREKFILDDVKSYAFLSNGSLPVPGVDDYAEFQATVKSMNIMGMTSEDFNSIFRIVSAVL 406
Query: 1084 LLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQ 1263
L G+++F QE+ +DQA L D+ V QK+ HLLGL V ++ +AFL PRIKVGR+FV KAQ +
Sbjct: 407 LFGSMKFRQERNNDQATLPDNTVAQKIAHLLGLSVTDMTRAFLTPRIKVGRDFVTKAQTK 466
Query: 1264 EQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQI 1443
EQ EFAVEAIAKA YER+FKWLV RIN+SLDRT RQGASFIGILD+AGFEIF++NSFEQ+
Sbjct: 467 EQVEFAVEAIAKACYERMFKWLVNRINRSLDRTKRQGASFIGILDMAGFEIFELNSFEQL 526
Query: 1444 CINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDE 1623
CINYTNEKLQQLFN+TMFILEQEEYQREGIEW FIDFGLDLQPTIDLI+KP G++ALLDE
Sbjct: 527 CINYTNEKLQQLFNHTMFILEQEEYQREGIEWKFIDFGLDLQPTIDLIDKPGGIMALLDE 586
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMDP 1803
EC FPKA DK+FV+KL H+ HPKF+ D R + FA+VHYAGRVDYSA +WLMKNMDP
Sbjct: 587 ECWFPKATDKTFVDKLVSAHSMHPKFMKTDFRGVADFAIVHYAGRVDYSAAKWLMKNMDP 646
Query: 1804 LNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLT 1983
LNEN+V L+Q S DPFV IWKDAE G+ + +T FG R+RKGMFRTVS L+KEQL
Sbjct: 647 LNENIVSLLQGSQDPFVVNIWKDAEIVGMAQQALTDTQFGARTRKGMFRTVSHLYKEQLA 706
Query: 1984 KLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQ 2163
KLM TLRNT+P+FVRCIIPNHEK++GKI++ LVL+QLRCNGVLEGIRICRQGFPNR+PFQ
Sbjct: 707 KLMDTLRNTNPNFVRCIIPNHEKRAGKIDAPLVLDQLRCNGVLEGIRICRQGFPNRIPFQ 766
Query: 2164 EFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEER 2343
EFR RYE+LTP+VIPK F+DGK++ KMI AL++D+NLYR+GQSK+FFR GVLAHLEEER
Sbjct: 767 EFRQRYELLTPNVIPKGFMDGKKACEKMIQALELDSNLYRVGQSKIFFRAGVLAHLEEER 826
Query: 2344 DLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVK 2523
D K++ LI+NFQA CRGFL+RR Y N AYLKLRNWQWWRL+TKVK
Sbjct: 827 DFKISDLIVNFQAFCRGFLARRNYQKRLQQLNAIRIIQRNCAAYLKLRNWQWWRLYTKVK 886
Query: 2524 PLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESEN 2703
PLL+VT+ ++++ K+DEL+ +E+L + + +E E+K Q +VE+ + EQLQ E E
Sbjct: 887 PLLEVTKQEEKLVQKEDELKQVREKLDTLAKNTQEYERKYQQALVEKTTLAEQLQAEIEL 946
Query: 2704 SAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXX 2883
AE ++ R RL R QELE ++ ++ R+ ++K ++D
Sbjct: 947 CAEAEESRSRLMARKQELEDMMQELETRIEEEEERVLALGGEKKKLELNIQDLEEQLEEE 1006
Query: 2884 XXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERA 3063
+K +D D L+ L + EE+A
Sbjct: 1007 EAARQKLQLEKVQLDAKIKKYEEDLALTDDQNQKLLKEKKLLEERANDLSQTLAEEEEKA 1066
Query: 3064 KHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELN 3243
KH K K + E + ELE+ L++++Q + E ++ KRK+ E+ D K+ L E+ +V+E+
Sbjct: 1067 KHLAKLKAKHEATITELEERLHKDQQQRQESDRSKRKIETEVADLKEQLNERRVQVDEMQ 1126
Query: 3244 NQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRR 3423
QL KR+EEL L R DEESA QK R++++ + E++ED+E E+ AR KAE RR
Sbjct: 1127 AQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAEKAARAKAEKVRR 1186
Query: 3424 EVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFS 3603
++ +LE +K ++LD +D Q+L S++++E+ K+++E+ EG + + + K S
Sbjct: 1187 DLSEELEALKNELLDSLDTTAAQQELRSKREQELATLKKSLEEETVNHEGVLADMRHKHS 1246
Query: 3604 RQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLM 3783
+++ ++DQ+E +K ++ LEK + + E AD+A E+ + +SR + D++RK E+ +
Sbjct: 1247 QELNSINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQENDRRRKQAESQIA 1306
Query: 3784 EIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXX 3963
E+Q LAE + + L ++ + + E +++ EE E + + +
Sbjct: 1307 ELQVKLAEIERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKSASNMESQLTEAQQ 1366
Query: 3964 XXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEE 4143
TR K+ ++ RQ+E EK AL ++ EE + + + E+++ E ++KAEE
Sbjct: 1367 LLEEETRQKLGLSSKLRQIESEKEALQEQLEEDDEAKRNYERKLAEVTTQMQEIKKKAEE 1426
Query: 4144 SVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRAS 4317
+ ++LEE +K+ +D+E L++Q++E +R+ +SKKKIQ ELED+++ELE R
Sbjct: 1427 DADLAKELEEGKKRLNKDIEALERQVKELIAQNDRLDKSKKKIQSELEDATIELEAQRTK 1486
Query: 4318 HRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEES 4497
+ EK+QK F+ +AEE+ ++ +RD +E R++ET+VLS+ E+D + +E+
Sbjct: 1487 VLELEKKQKNFDKILAEEKAISEQIAQERDTAEREAREKETKVLSVSRELDEAFDKIEDL 1546
Query: 4498 DRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDAR 4677
+ R++LQ EL D + + KNVHELEKAKR+LE++L +++ Q EELED+LQ+ EDA+
Sbjct: 1547 ENKRKTLQNELDDLANTQGTADKNVHELEKAKRALESQLAELKAQNEELEDDLQLTEDAK 1606
Query: 4678 LRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKI 4857
LRLEV QAL+S+ +R + K+ AEEKRRGL+KQ+RDLE EL+ E++ ++ AV+ +KK+
Sbjct: 1607 LRLEVNMQALRSQFERDLLAKEEGAEEKRRGLVKQLRDLETELDEERKQRTAAVASKKKL 1666
Query: 4858 ENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKF 5037
E + E+E +E+ N++KE+ + + EEA+ AKE++ AL +EAD K
Sbjct: 1667 EGDLKEIETTMEMHNKVKEDALKHAKKLQAQVKDALRDAEEAKAAKEELQALSKEADGKV 1726
Query: 5038 RAVEAEREQLRE---ANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXX 5208
+A+EAE QL E ++E +A + A G + +EKRRLEA+IA
Sbjct: 1727 KALEAEVLQLTEDLASSERARRAAETERDELAEEIANNANKGSLMIDEKRRLEARIATLE 1786
Query: 5209 XXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKIT 5388
QSN E+ +D+ RKAQ+Q+EQ+TT+L+ E++ +QK E + LER N++ KAK+
Sbjct: 1787 EELEEEQSNSEVLLDRSRKAQLQIEQLTTELANEKSNSQKNENGRALLERQNKELKAKLA 1846
Query: 5389 ELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEK 5568
E+E+ +++ +A +A LEAK+ LE+QL EG+E+ +A R+++K++ + T EDE+
Sbjct: 1847 EIETAQRTKVKATIATLEAKIANLEEQLENEGKERLLQQKANRKMDKKIKELTMNIEDER 1906
Query: 5569 RANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
R +Q KE ++K N + + L+R LDE E+E+ +E+T+ R QRE +D++++ E + RE+
Sbjct: 1907 RHVDQHKEQMDKLNSRIKLLKRNLDETEEELQKEKTQKRKYQRECEDMIESQEAMNREI 1965
Score = 160 bits (405), Expect = 3e-37
Identities = 192/935 (20%), Positives = 386/935 (40%), Gaps = 55/935 (5%)
Frame = +1
Query: 2530 LQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSA 2709
+QV ++ +++EL T R+ + +K ++ + A IQE L+ E A
Sbjct: 1120 VQVDEMQAQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAEKAARA 1179
Query: 2710 ELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXX 2889
+ + +R L ++ELE + N++ D L R +++ T++
Sbjct: 1180 KAEKVRRDL---SEELEALKNELLDSLDTTAAQQELRSK-REQELATLKKSLEEETVNHE 1235
Query: 2890 XXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKH 3069
K + Q + A L T+L +
Sbjct: 1236 GVLADMRHKHS--QELNSINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQE 1293
Query: 3070 GVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQ 3249
+ + + E+Q+ EL+ L + +SEL++ KL E E+ + L E K
Sbjct: 1294 NDRRRKQAESQIAELQVKLAEIERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKS 1353
Query: 3250 LMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREV 3429
+ +L +EE+ + ++R +++ + L+E +E + A+ E EV
Sbjct: 1354 ASNMESQLTEAQQLLEEETRQKLGLSSKLRQIESEKEALQEQLEEDDEAKRNYERKLAEV 1413
Query: 3430 VAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQ 3609
Q++++K + D A L++ R ++++ A +R ++++ ++++ K K +
Sbjct: 1414 TTQMQEIKKKAEEDADLAKELEEGKKRLNKDIEALERQVKELI-AQNDRLDKSKKKIQSE 1472
Query: 3610 VEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEI 3789
+E+ ++E + + +LEK+Q D+ A+ + R +++ + E ++ +
Sbjct: 1473 LEDATIELEAQRTKVLELEKKQKNFDKILAEEKAISEQIAQERDTAEREAREKETKVLSV 1532
Query: 3790 QANLAESDEHKRTLIDQLERSRDELDHLNRVR---EEEEHAFANMQRRLATAXXXXXXXX 3960
L E+ + L ++ + ++ELD L + ++ H +R L +
Sbjct: 1533 SRELDEAFDKIEDLENKRKTLQNELDDLANTQGTADKNVHELEKAKRALESQLA------ 1586
Query: 3961 XXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAE 4140
LK N L+ ++A L + + LR+ E+++ A +GA E RR
Sbjct: 1587 -------ELKAQNEELEDDLQLTEDAKLRLEVNMQALRSQFERDLLAKEEGAEEKRRGLV 1639
Query: 4141 ESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASH 4320
K LRD+E +L+E + + SKKK++ +L++ +E
Sbjct: 1640 ------------KQLRDLE---TELDEERKQRTAAVASKKKLEGDLKEIETTMEMHNKVK 1684
Query: 4321 RDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESD 4500
D+ K KK ++Q+ + ++A ++ + ++ + +V +L EV + E L S+
Sbjct: 1685 EDALKHAKKLQAQVKDALRDAEEAKAAKEELQALSKEADGKVKALEAEVLQLTEDLASSE 1744
Query: 4501 RVRRSLQ---QELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAED 4671
R RR+ + EL + I+N + G + + KR LEA + + ++EE + N ++ D
Sbjct: 1745 RARRAAETERDELAEEIANNANKGSLMID---EKRRLEARIATLEEELEEEQSNSEVLLD 1801
Query: 4672 ----ARLRLEVTNQAL--------KSESDRAI---SNKDVEA-----EEKRRGLLK---- 4779
A+L++E L K+E+ RA+ NK+++A E +R +K
Sbjct: 1802 RSRKAQLQIEQLTTELANEKSNSQKNENGRALLERQNKELKAKLAEIETAQRTKVKATIA 1861
Query: 4780 ----QIRDLENELENEKRGKSGAVSHRKKIENQIGEL---------------EQQLEVAN 4902
+I +LE +LENE + + +K++ +I EL EQ ++ +
Sbjct: 1862 TLEAKIANLEEQLENEGKERLLQQKANRKMDKKIKELTMNIEDERRHVDQHKEQMDKLNS 1921
Query: 4903 RLK------EEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQ 5064
R+K +E +YQ ECE+ +++E + + K R
Sbjct: 1922 RIKLLKRNLDETEEELQKEKTQKRKYQRECEDMIESQEAMNREINSLKTKLR-------- 1973
Query: 5065 LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSE 5169
R GL +R RA GGG S +
Sbjct: 1974 -RTGGIGLSSSR-----LTGTPSSKRAGGGGGSDD 2002
>gi|547969|sp|Q99323|MYSN_DROME Myosin heavy chain, non-muscle (Zipper
protein) (Myosin II)
gi|103264|pir||A36014 myosin heavy chain, nonmuscle - fruit fly
(Drosophila melanogaster)
Length = 2017
Score = 1836 bits (4756), Expect = 0.0
Identities = 940/1919 (48%), Positives = 1316/1919 (67%), Gaps = 6/1919 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRK-LCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQ 183
+L+YL V+R R L WVP +N+GF+ SIKRE DEV VEL +T ++
Sbjct: 56 ELKYLSVERNQFNPIRPRRPSGHRSVLVWVPHENQGFVAASIKREHGDEVEVELAETGKR 115
Query: 184 VTISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPY 363
V I RDD+QK NPPKFDK+EDM+ELT LNEASVLHN+KDRYYS LIYTYSGLFCVV+NPY
Sbjct: 116 VMILRDDIQKMNPPKFDKVEDMAELTCLNEASVLHNIKDRYYSGLIYTYSGLFCVVVNPY 175
Query: 364 KKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENT 543
KKLPIY+E ++E +KG KRHE+PPH+FAI D+AYR+ML +REDQSILCTGESGAGKTENT
Sbjct: 176 KKLPIYTEKIMERYKGIKRHEVPPHVFAITDSAYRNMLGDREDQSILCTGESGAGKTENT 235
Query: 544 KKVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTV 723
KKVIQ+LA+VA A++ K A ++ IGELE QLLQANPILEAFGN+KTV
Sbjct: 236 KKVIQFLAYVA-ASKPKGSGAVPHPAVL--------IGELEQQLLQANPILEAFGNAKTV 286
Query: 724 KNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAK 903
KNDNSSRFGKFIRINFD SG+ISGANIE YLLEKSR +RQA+DER+FHIFYQ+L G + +
Sbjct: 287 KNDNSSRFGKFIRINFDASGFISGANIETYLLEKSRAIRQAKDERTFHIFYQLLAGATPE 346
Query: 904 EKSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVL 1083
++ +++L+ V +Y FL N + +P VDD EF +T+ SM IMG ++ +SI R+VSAVL
Sbjct: 347 QREKFILDDVKSYAFLSNGSLPVPGVDDYAEFQATVKSMNIMGMTSEDFNSIFRIVSAVL 406
Query: 1084 LLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQ 1263
L G+++F QE+ +DQA L D+ V QK+ HLLGL V ++ +AFL PRIKVGR+FV KAQ +
Sbjct: 407 LFGSMKFRQERNNDQATLPDNTVAQKIAHLLGLSVTDMTRAFLTPRIKVGRDFVTKAQTK 466
Query: 1264 EQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQI 1443
EQ EFAVEAIAKA YER+FKWLV RIN+SLDRT RQGASFIGILD+AGFEIF++NSFEQ+
Sbjct: 467 EQVEFAVEAIAKACYERMFKWLVNRINRSLDRTKRQGASFIGILDMAGFEIFELNSFEQL 526
Query: 1444 CINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDE 1623
CINYTNEKLQQLFN+TMFILEQEEYQREGIEW FIDFGLDLQPTIDLI+KP G++ALLDE
Sbjct: 527 CINYTNEKLQQLFNHTMFILEQEEYQREGIEWKFIDFGLDLQPTIDLIDKPGGIMALLDE 586
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMDP 1803
EC FPKA DK+FV+KL H+ HPKF+ D R + FA+VHYAGRVDYSA +WLMKNMDP
Sbjct: 587 ECWFPKATDKTFVDKLVSAHSMHPKFMKTDFRGVADFAIVHYAGRVDYSAAKWLMKNMDP 646
Query: 1804 LNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLT 1983
LNEN+V L+Q S DPFV IWKDAE G+ + +T FG R+RKGMFRTVS L+KEQL
Sbjct: 647 LNENIVSLLQGSQDPFVVNIWKDAEIVGMAQQALTDTQFGARTRKGMFRTVSHLYKEQLA 706
Query: 1984 KLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQ 2163
KLM TLRNT+P+FVRCIIPNHEK++GKI++ LVL+QLRCNGVLEGIRICRQGFPNR+PFQ
Sbjct: 707 KLMDTLRNTNPNFVRCIIPNHEKRAGKIDAPLVLDQLRCNGVLEGIRICRQGFPNRIPFQ 766
Query: 2164 EFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEER 2343
EFR RYE+LTP+VIPK F+DGK++ KMI AL++D+NLYR+GQSK+FFR GVLAHLEEER
Sbjct: 767 EFRQRYELLTPNVIPKGFMDGKKACEKMIQALELDSNLYRVGQSKIFFRAGVLAHLEEER 826
Query: 2344 DLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVK 2523
D K++ LI+NFQA CRGFL+RR Y N AYLKLRNWQWWRL+TKVK
Sbjct: 827 DFKISDLIVNFQAFCRGFLARRNYQKRLQQLNAIRIIQRNCAAYLKLRNWQWWRLYTKVK 886
Query: 2524 PLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESEN 2703
PLL+VT+ ++++ K+DEL+ +E+L + + +E E+K Q +VE+ + EQLQ E E
Sbjct: 887 PLLEVTKQEEKLVQKEDELKQVREKLDTLAKNTQEYERKYQQALVEKTTLAEQLQAEIEL 946
Query: 2704 SAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXX 2883
AE ++ R RL R QELE ++ ++ R+ ++K ++D
Sbjct: 947 CAEAEESRSRLMARKQELEDMMQELETRIEEEEERVLALGGEKKKLELNIQDLEEQLEEE 1006
Query: 2884 XXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERA 3063
+K +D D L+ L + EE+A
Sbjct: 1007 EAARQKLQLEKVQLDAKIKKYEEDLALTDDQNQKLLKEKKLLEERANDLSQTLAEEEEKA 1066
Query: 3064 KHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELN 3243
KH K K + E + ELE+ L++++Q + E ++ KRK+ E+ D K+ L E+ +V+E+
Sbjct: 1067 KHLAKLKAKHEATITELEERLHKDQQQRQESDRSKRKIETEVADLKEQLNERRVQVDEMQ 1126
Query: 3244 NQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRR 3423
QL KR+EEL L R DEESA QK R++++ + E++ED+E E+ AR KAE RR
Sbjct: 1127 AQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAEKAARAKAEKVRR 1186
Query: 3424 EVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFS 3603
++ +LE +K ++LD +D Q+L S++++E+ K+++E+ EG + + + K S
Sbjct: 1187 DLSEELEALKNELLDSLDTTAAQQELRSKREQELATLKKSLEEETVNHEGVLADMRHKHS 1246
Query: 3604 RQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLM 3783
+++ ++DQ+E +K ++ LEK + + E AD+A E+ + +SR + D++RK E+ +
Sbjct: 1247 QELNSINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQENDRRRKQAESQIA 1306
Query: 3784 EIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXX 3963
E+Q LAE + + L ++ + + E +++ EE E + + +
Sbjct: 1307 ELQVKLAEIERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKSASNMESQLTEAQQ 1366
Query: 3964 XXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEE 4143
TR K+ ++ RQ+E EK AL ++ EE + + + E+++ E ++KAEE
Sbjct: 1367 LLEEETRQKLGLSSKLRQIESEKEALQEQLEEDDEAKRNYERKLAEVTTQMQEIKKKAEE 1426
Query: 4144 SVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRAS 4317
+ ++LEE +K+ +D+E L++Q++E +R+ +SKKKIQ ELED+++ELE R
Sbjct: 1427 DADLAKELEEGKKRLNKDIEALERQVKELIAQNDRLDKSKKKIQSELEDATIELEAQRTK 1486
Query: 4318 HRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEES 4497
+ EK+QK F+ +AEE+ ++ +RD +E R++ET+VLS+ E+D + +E+
Sbjct: 1487 VLELEKKQKNFDKILAEEKAISEQIAQERDTAEREAREKETKVLSVSRELDEAFDKIEDL 1546
Query: 4498 DRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDAR 4677
+ R++LQ EL D + + KNVHELEKAKR+LE++L +++ Q EELED+LQ+ EDA+
Sbjct: 1547 ENKRKTLQNELDDLANTQGTADKNVHELEKAKRALESQLAELKAQNEELEDDLQLTEDAK 1606
Query: 4678 LRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKI 4857
LRLEV QAL+S+ +R + K+ AEEKRRGL+KQ+RDLE EL+ E++ ++ AV+ +KK+
Sbjct: 1607 LRLEVNMQALRSQFERDLLAKEEGAEEKRRGLVKQLRDLETELDEERKQRTAAVASKKKL 1666
Query: 4858 ENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKF 5037
E + E+E +E+ N++KE+ + + EEA+ AKE++ AL +EAD K
Sbjct: 1667 EGDLKEIETTMEMHNKVKEDALKHAKKLQAQVKDALRDAEEAKAAKEELQALSKEADGKV 1726
Query: 5038 RAVEAEREQLRE---ANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXX 5208
+A+EAE QL E ++E +A + A G + +EKRRLEA+IA
Sbjct: 1727 KALEAEVLQLTEDLASSERARRAAETERDELAEEIANNANKGSLMIDEKRRLEARIATLE 1786
Query: 5209 XXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKIT 5388
QSN E+ +D+ Q+Q+EQ+TT+L+ E++ +QK E + LER N++ KAK+
Sbjct: 1787 EELEEEQSNSEVLLDRAAARQLQIEQLTTELANEKSNSQKNENGRALLERQNKELKAKLA 1846
Query: 5389 ELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEK 5568
E+E+ +++ +A +A LEAK+ +E+QL EG+E+ +A R+++K++ + T EDE+
Sbjct: 1847 EIETAQRTKVKATIATLEAKIAKVEEQLENEGKERLLQQKANRKMDKKIKELTMNIEDER 1906
Query: 5569 RANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
R +Q KE ++K N + + L+R LDE E+E+ +E+T+ R QRE +D++++ E + RE+
Sbjct: 1907 RHVDQHKEQMDKLNSRIKLLKRNLDETEEELQKEKTQKRKYQRECEDMIESQEAMNREI 1965
Score = 158 bits (399), Expect = 2e-36
Identities = 190/935 (20%), Positives = 385/935 (40%), Gaps = 55/935 (5%)
Frame = +1
Query: 2530 LQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSA 2709
+QV ++ +++EL T R+ + +K ++ + A IQE L+ E A
Sbjct: 1120 VQVDEMQAQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAEKAARA 1179
Query: 2710 ELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXX 2889
+ + +R L ++ELE + N++ D L R +++ T++
Sbjct: 1180 KAEKVRRDL---SEELEALKNELLDSLDTTAAQQELRSK-REQELATLKKSLEEETVNHE 1235
Query: 2890 XXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKH 3069
K + Q + A L T+L +
Sbjct: 1236 GVLADMRHKHS--QELNSINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQE 1293
Query: 3070 GVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQ 3249
+ + + E+Q+ EL+ L + +SEL++ KL E E+ + L E K
Sbjct: 1294 NDRRRKQAESQIAELQVKLAEIERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKS 1353
Query: 3250 LMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREV 3429
+ +L +EE+ + ++R +++ + L+E +E + A+ E EV
Sbjct: 1354 ASNMESQLTEAQQLLEEETRQKLGLSSKLRQIESEKEALQEQLEEDDEAKRNYERKLAEV 1413
Query: 3430 VAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQ 3609
Q++++K + D A L++ R ++++ A +R ++++ ++++ K K +
Sbjct: 1414 TTQMQEIKKKAEEDADLAKELEEGKKRLNKDIEALERQVKELI-AQNDRLDKSKKKIQSE 1472
Query: 3610 VEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEI 3789
+E+ ++E + + +LEK+Q D+ A+ + R +++ + E ++ +
Sbjct: 1473 LEDATIELEAQRTKVLELEKKQKNFDKILAEEKAISEQIAQERDTAEREAREKETKVLSV 1532
Query: 3790 QANLAESDEHKRTLIDQLERSRDELDHLNRVR---EEEEHAFANMQRRLATAXXXXXXXX 3960
L E+ + L ++ + ++ELD L + ++ H +R L +
Sbjct: 1533 SRELDEAFDKIEDLENKRKTLQNELDDLANTQGTADKNVHELEKAKRALESQLA------ 1586
Query: 3961 XXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAE 4140
LK N L+ ++A L + + LR+ E+++ A +GA E RR
Sbjct: 1587 -------ELKAQNEELEDDLQLTEDAKLRLEVNMQALRSQFERDLLAKEEGAEEKRRGLV 1639
Query: 4141 ESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASH 4320
K LRD+E +L+E + + SKKK++ +L++ +E
Sbjct: 1640 ------------KQLRDLE---TELDEERKQRTAAVASKKKLEGDLKEIETTMEMHNKVK 1684
Query: 4321 RDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESD 4500
D+ K KK ++Q+ + ++A ++ + ++ + +V +L EV + E L S+
Sbjct: 1685 EDALKHAKKLQAQVKDALRDAEEAKAAKEELQALSKEADGKVKALEAEVLQLTEDLASSE 1744
Query: 4501 RVRRSLQ---QELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAED 4671
R RR+ + EL + I+N + G + + KR LEA + + ++EE + N ++ D
Sbjct: 1745 RARRAAETERDELAEEIANNANKGSLMID---EKRRLEARIATLEEELEEEQSNSEVLLD 1801
Query: 4672 A---------RLRLEVTNQ---ALKSESDRAI---SNKDVEA-----EEKRRGLLK---- 4779
+L E+ N+ + K+E+ RA+ NK+++A E +R +K
Sbjct: 1802 RAAARQLQIEQLTTELANEKSNSQKNENGRALLERQNKELKAKLAEIETAQRTKVKATIA 1861
Query: 4780 ----QIRDLENELENEKRGKSGAVSHRKKIENQIGEL---------------EQQLEVAN 4902
+I +E +LENE + + +K++ +I EL EQ ++ +
Sbjct: 1862 TLEAKIAKVEEQLENEGKERLLQQKANRKMDKKIKELTMNIEDERRHVDQHKEQMDKLNS 1921
Query: 4903 RLK------EEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQ 5064
R+K +E +YQ ECE+ +++E + + K R
Sbjct: 1922 RIKLLKRNLDETEEELQKEKTQKRKYQRECEDMIESQEAMNREINSLKTKLR-------- 1973
Query: 5065 LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSE 5169
R GL +R RA GGG S +
Sbjct: 1974 -RTGGIGLSSSR-----LTGTPSSKRAGGGGGSDD 2002
>gi|157953|gb|AAA28713.1| non-muscle myosin heavy chain
Length = 1972
Score = 1836 bits (4756), Expect = 0.0
Identities = 940/1919 (48%), Positives = 1316/1919 (67%), Gaps = 6/1919 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRK-LCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQ 183
+L+YL V+R R L WVP +N+GF+ SIKRE DEV VEL +T ++
Sbjct: 11 ELKYLSVERNQFNPIRPRRPSGHRSVLVWVPHENQGFVAASIKREHGDEVEVELAETGKR 70
Query: 184 VTISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPY 363
V I RDD+QK NPPKFDK+EDM+ELT LNEASVLHN+KDRYYS LIYTYSGLFCVV+NPY
Sbjct: 71 VMILRDDIQKMNPPKFDKVEDMAELTCLNEASVLHNIKDRYYSGLIYTYSGLFCVVVNPY 130
Query: 364 KKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENT 543
KKLPIY+E ++E +KG KRHE+PPH+FAI D+AYR+ML +REDQSILCTGESGAGKTENT
Sbjct: 131 KKLPIYTEKIMERYKGIKRHEVPPHVFAITDSAYRNMLGDREDQSILCTGESGAGKTENT 190
Query: 544 KKVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTV 723
KKVIQ+LA+VA A++ K A ++ IGELE QLLQANPILEAFGN+KTV
Sbjct: 191 KKVIQFLAYVA-ASKPKGSGAVPHPAVL--------IGELEQQLLQANPILEAFGNAKTV 241
Query: 724 KNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAK 903
KNDNSSRFGKFIRINFD SG+ISGANIE YLLEKSR +RQA+DER+FHIFYQ+L G + +
Sbjct: 242 KNDNSSRFGKFIRINFDASGFISGANIETYLLEKSRAIRQAKDERTFHIFYQLLAGATPE 301
Query: 904 EKSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVL 1083
++ +++L+ V +Y FL N + +P VDD EF +T+ SM IMG ++ +SI R+VSAVL
Sbjct: 302 QREKFILDDVKSYAFLSNGSLPVPGVDDYAEFQATVKSMNIMGMTSEDFNSIFRIVSAVL 361
Query: 1084 LLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQ 1263
L G+++F QE+ +DQA L D+ V QK+ HLLGL V ++ +AFL PRIKVGR+FV KAQ +
Sbjct: 362 LFGSMKFRQERNNDQATLPDNTVAQKIAHLLGLSVTDMTRAFLTPRIKVGRDFVTKAQTK 421
Query: 1264 EQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQI 1443
EQ EFAVEAIAKA YER+FKWLV RIN+SLDRT RQGASFIGILD+AGFEIF++NSFEQ+
Sbjct: 422 EQVEFAVEAIAKACYERMFKWLVNRINRSLDRTKRQGASFIGILDMAGFEIFELNSFEQL 481
Query: 1444 CINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDE 1623
CINYTNEKLQQLFN+TMFILEQEEYQREGIEW FIDFGLDLQPTIDLI+KP G++ALLDE
Sbjct: 482 CINYTNEKLQQLFNHTMFILEQEEYQREGIEWKFIDFGLDLQPTIDLIDKPGGIMALLDE 541
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMDP 1803
EC FPKA DK+FV+KL H+ HPKF+ D R + FA+VHYAGRVDYSA +WLMKNMDP
Sbjct: 542 ECWFPKATDKTFVDKLVSAHSMHPKFMKTDFRGVADFAIVHYAGRVDYSAAKWLMKNMDP 601
Query: 1804 LNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLT 1983
LNEN+V L+Q S DPFV IWKDAE G+ + +T FG R+RKGMFRTVS L+KEQL
Sbjct: 602 LNENIVSLLQGSQDPFVVNIWKDAEIVGMAQQALTDTQFGARTRKGMFRTVSHLYKEQLA 661
Query: 1984 KLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQ 2163
KLM TLRNT+P+FVRCIIPNHEK++GKI++ LVL+QLRCNGVLEGIRICRQGFPNR+PFQ
Sbjct: 662 KLMDTLRNTNPNFVRCIIPNHEKRAGKIDAPLVLDQLRCNGVLEGIRICRQGFPNRIPFQ 721
Query: 2164 EFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEER 2343
EFR RYE+LTP+VIPK F+DGK++ KMI AL++D+NLYR+GQSK+FFR GVLAHLEEER
Sbjct: 722 EFRQRYELLTPNVIPKGFMDGKKACEKMIQALELDSNLYRVGQSKIFFRAGVLAHLEEER 781
Query: 2344 DLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVK 2523
D K++ LI+NFQA CRGFL+RR Y N AYLKLRNWQWWRL+TKVK
Sbjct: 782 DFKISDLIVNFQAFCRGFLARRNYQKRLQQLNAIRIIQRNCAAYLKLRNWQWWRLYTKVK 841
Query: 2524 PLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESEN 2703
PLL+VT+ ++++ K+DEL+ +E+L + + +E E+K Q +VE+ + EQLQ E E
Sbjct: 842 PLLEVTKQEEKLVQKEDELKQVREKLDTLAKNTQEYERKYQQALVEKTTLAEQLQAEIEL 901
Query: 2704 SAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXX 2883
AE ++ R RL R QELE ++ ++ R+ ++K ++D
Sbjct: 902 CAEAEESRSRLMARKQELEDMMQELETRIEEEEERVLALGGEKKKLELNIQDLEEQLEEE 961
Query: 2884 XXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERA 3063
+K +D D L+ L + EE+A
Sbjct: 962 EAARQKLQLEKVQLDAKIKKYEEDLALTDDQNQKLLKEKKLLEERANDLSQTLAEEEEKA 1021
Query: 3064 KHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELN 3243
KH K K + E + ELE+ L++++Q + E ++ KRK+ E+ D K+ L E+ +V+E+
Sbjct: 1022 KHLAKLKAKHEATITELEERLHKDQQQRQESDRSKRKIETEVADLKEQLNERRVQVDEMQ 1081
Query: 3244 NQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRR 3423
QL KR+EEL L R DEESA QK R++++ + E++ED+E E+ AR KAE RR
Sbjct: 1082 AQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAEKAARAKAEKVRR 1141
Query: 3424 EVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFS 3603
++ +LE +K ++LD +D Q+L S++++E+ K+++E+ EG + + + K S
Sbjct: 1142 DLSEELEALKNELLDSLDTTAAQQELRSKREQELATLKKSLEEETVNHEGVLADMRHKHS 1201
Query: 3604 RQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLM 3783
+++ ++DQ+E +K ++ LEK + + E AD+A E+ + +SR + D++RK E+ +
Sbjct: 1202 QELNSINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQENDRRRKQAESQIA 1261
Query: 3784 EIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXX 3963
E+Q LAE + + L ++ + + E +++ EE E + + +
Sbjct: 1262 ELQVKLAEIERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKSASNMESQLTEAQQ 1321
Query: 3964 XXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEE 4143
TR K+ ++ RQ+E EK AL ++ EE + + + E+++ E ++KAEE
Sbjct: 1322 LLEEETRQKLGLSSKLRQIESEKEALQEQLEEDDEAKRNYERKLAEVTTQMQEIKKKAEE 1381
Query: 4144 SVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRAS 4317
+ ++LEE +K+ +D+E L++Q++E +R+ +SKKKIQ ELED+++ELE R
Sbjct: 1382 DADLAKELEEGKKRLNKDIEALERQVKELIAQNDRLDKSKKKIQSELEDATIELEAQRTK 1441
Query: 4318 HRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEES 4497
+ EK+QK F+ +AEE+ ++ +RD +E R++ET+VLS+ E+D + +E+
Sbjct: 1442 VLELEKKQKNFDKILAEEKAISEQIAQERDTAEREAREKETKVLSVSRELDEAFDKIEDL 1501
Query: 4498 DRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDAR 4677
+ R++LQ EL D + + KNVHELEKAKR+LE++L +++ Q EELED+LQ+ EDA+
Sbjct: 1502 ENKRKTLQNELDDLANTQGTADKNVHELEKAKRALESQLAELKAQNEELEDDLQLTEDAK 1561
Query: 4678 LRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKI 4857
LRLEV QAL+S+ +R + K+ AEEKRRGL+KQ+RDLE EL+ E++ ++ AV+ +KK+
Sbjct: 1562 LRLEVNMQALRSQFERDLLAKEEGAEEKRRGLVKQLRDLETELDEERKQRTAAVASKKKL 1621
Query: 4858 ENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKF 5037
E + E+E +E+ N++KE+ + + EEA+ AKE++ AL +EAD K
Sbjct: 1622 EGDLKEIETTMEMHNKVKEDALKHAKKLQAQVKDALRDAEEAKAAKEELQALSKEADGKV 1681
Query: 5038 RAVEAEREQLRE---ANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXX 5208
+A+EAE QL E ++E +A + A G + +EKRRLEA+IA
Sbjct: 1682 KALEAEVLQLTEDLASSERARRAAETERDELAEEIANNANKGSLMIDEKRRLEARIATLE 1741
Query: 5209 XXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKIT 5388
QSN E+ +D+ Q+Q+EQ+TT+L+ E++ +QK E + LER N++ KAK+
Sbjct: 1742 EELEEEQSNSEVLLDRAAARQLQIEQLTTELANEKSNSQKNENGRALLERQNKELKAKLA 1801
Query: 5389 ELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEK 5568
E+E+ +++ +A +A LEAK+ +E+QL EG+E+ +A R+++K++ + T EDE+
Sbjct: 1802 EIETAQRTKVKATIATLEAKIAKVEEQLENEGKERLLQQKANRKMDKKIKELTMNIEDER 1861
Query: 5569 RANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
R +Q KE ++K N + + L+R LDE E+E+ +E+T+ R QRE +D++++ E + RE+
Sbjct: 1862 RHVDQHKEQMDKLNSRIKLLKRNLDETEEELQKEKTQKRKYQRECEDMIESQEAMNREI 1920
Score = 158 bits (399), Expect = 2e-36
Identities = 190/935 (20%), Positives = 385/935 (40%), Gaps = 55/935 (5%)
Frame = +1
Query: 2530 LQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSA 2709
+QV ++ +++EL T R+ + +K ++ + A IQE L+ E A
Sbjct: 1075 VQVDEMQAQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAEKAARA 1134
Query: 2710 ELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXX 2889
+ + +R L ++ELE + N++ D L R +++ T++
Sbjct: 1135 KAEKVRRDL---SEELEALKNELLDSLDTTAAQQELRSK-REQELATLKKSLEEETVNHE 1190
Query: 2890 XXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKH 3069
K + Q + A L T+L +
Sbjct: 1191 GVLADMRHKHS--QELNSINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQE 1248
Query: 3070 GVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQ 3249
+ + + E+Q+ EL+ L + +SEL++ KL E E+ + L E K
Sbjct: 1249 NDRRRKQAESQIAELQVKLAEIERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKS 1308
Query: 3250 LMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREV 3429
+ +L +EE+ + ++R +++ + L+E +E + A+ E EV
Sbjct: 1309 ASNMESQLTEAQQLLEEETRQKLGLSSKLRQIESEKEALQEQLEEDDEAKRNYERKLAEV 1368
Query: 3430 VAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQ 3609
Q++++K + D A L++ R ++++ A +R ++++ ++++ K K +
Sbjct: 1369 TTQMQEIKKKAEEDADLAKELEEGKKRLNKDIEALERQVKELI-AQNDRLDKSKKKIQSE 1427
Query: 3610 VEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEI 3789
+E+ ++E + + +LEK+Q D+ A+ + R +++ + E ++ +
Sbjct: 1428 LEDATIELEAQRTKVLELEKKQKNFDKILAEEKAISEQIAQERDTAEREAREKETKVLSV 1487
Query: 3790 QANLAESDEHKRTLIDQLERSRDELDHLNRVR---EEEEHAFANMQRRLATAXXXXXXXX 3960
L E+ + L ++ + ++ELD L + ++ H +R L +
Sbjct: 1488 SRELDEAFDKIEDLENKRKTLQNELDDLANTQGTADKNVHELEKAKRALESQLA------ 1541
Query: 3961 XXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAE 4140
LK N L+ ++A L + + LR+ E+++ A +GA E RR
Sbjct: 1542 -------ELKAQNEELEDDLQLTEDAKLRLEVNMQALRSQFERDLLAKEEGAEEKRRGLV 1594
Query: 4141 ESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASH 4320
K LRD+E +L+E + + SKKK++ +L++ +E
Sbjct: 1595 ------------KQLRDLE---TELDEERKQRTAAVASKKKLEGDLKEIETTMEMHNKVK 1639
Query: 4321 RDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESD 4500
D+ K KK ++Q+ + ++A ++ + ++ + +V +L EV + E L S+
Sbjct: 1640 EDALKHAKKLQAQVKDALRDAEEAKAAKEELQALSKEADGKVKALEAEVLQLTEDLASSE 1699
Query: 4501 RVRRSLQ---QELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAED 4671
R RR+ + EL + I+N + G + + KR LEA + + ++EE + N ++ D
Sbjct: 1700 RARRAAETERDELAEEIANNANKGSLMID---EKRRLEARIATLEEELEEEQSNSEVLLD 1756
Query: 4672 A---------RLRLEVTNQ---ALKSESDRAI---SNKDVEA-----EEKRRGLLK---- 4779
+L E+ N+ + K+E+ RA+ NK+++A E +R +K
Sbjct: 1757 RAAARQLQIEQLTTELANEKSNSQKNENGRALLERQNKELKAKLAEIETAQRTKVKATIA 1816
Query: 4780 ----QIRDLENELENEKRGKSGAVSHRKKIENQIGEL---------------EQQLEVAN 4902
+I +E +LENE + + +K++ +I EL EQ ++ +
Sbjct: 1817 TLEAKIAKVEEQLENEGKERLLQQKANRKMDKKIKELTMNIEDERRHVDQHKEQMDKLNS 1876
Query: 4903 RLK------EEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQ 5064
R+K +E +YQ ECE+ +++E + + K R
Sbjct: 1877 RIKLLKRNLDETEEELQKEKTQKRKYQRECEDMIESQEAMNREINSLKTKLR-------- 1928
Query: 5065 LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSE 5169
R GL +R RA GGG S +
Sbjct: 1929 -RTGGIGLSSSR-----LTGTPSSKRAGGGGGSDD 1957
>gi|1572482|gb|AAB09050.1| nonmuscle myosin-II heavy chain [Drosophila
melanogaster]
Length = 2012
Score = 1835 bits (4752), Expect = 0.0
Identities = 948/1950 (48%), Positives = 1323/1950 (67%), Gaps = 37/1950 (1%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRK-LCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQ 183
+L+YL V+R R L WVP +N+GF+ SIKRE DEV VEL +T ++
Sbjct: 11 ELKYLSVERNQFNPIRPRRPSGHRSVLVWVPHENQGFVAASIKREHGDEVEVELAETGKR 70
Query: 184 VTISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPY 363
V I RDD+QK NPPKFDK+EDM+ELT LNEASVLHN+KDRYYS LIYTYSGLFCVV+NPY
Sbjct: 71 VMILRDDIQKMNPPKFDKVEDMAELTCLNEASVLHNIKDRYYSGLIYTYSGLFCVVVNPY 130
Query: 364 KKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENT 543
KKLPIY+E ++E +KG KRHE+PPH+FAI D+AYR+ML +REDQSILCTGESGAGKTENT
Sbjct: 131 KKLPIYTEKIMERYKGIKRHEVPPHVFAITDSAYRNMLGDREDQSILCTGESGAGKTENT 190
Query: 544 KKVIQYLAHVAGATR-------------NKSLNA-------AAQQNIVQKPDVRNPI--- 654
KKVIQ+LA+VA + N S+N QN Q +V N +
Sbjct: 191 KKVIQFLAYVAASKPKGSGAVPHPAVLINFSVNTNKYIKVKIMAQNQNQTIEVVNGLKMV 250
Query: 655 --------GELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIEF 810
GELE QLLQANPILEAFGN+KTVKNDNSSRFGKFIRINFD SG+ISGANIE
Sbjct: 251 EVNSNCQEGELEQQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDASGFISGANIET 310
Query: 811 YLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRFLVNRGITLPNVDDV 990
YLLEKSR +RQA+DER+FHIFYQ+L G + +++ +++L+ V +Y FL N + +P VDD
Sbjct: 311 YLLEKSRAIRQAKDERTFHIFYQLLAGATPEQREKFILDDVKSYAFLSNGSLPVPGVDDY 370
Query: 991 QEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQKVCH 1170
EF +T+ SM IMG ++ +SI R+VSAVLL G+++F QE+ +DQA L D+ V QK+ H
Sbjct: 371 AEFQATVKSMNIMGMTSEDFNSIFRIVSAVLLFGSMKFRQERNNDQATLPDNTVAQKIAH 430
Query: 1171 LLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRINKS 1350
LLGL V ++ +AFL PRIKVGR+FV KAQ +EQ EFAVEAIAKA YER+FKWLV RIN+S
Sbjct: 431 LLGLSVTDMTRAFLTPRIKVGRDFVTKAQTKEQVEFAVEAIAKACYERMFKWLVNRINRS 490
Query: 1351 LDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQREG 1530
LDRT RQGASFIGILD+AGFEIF++NSFEQ+CINYTNEKLQQLFN+TMFILEQEEYQREG
Sbjct: 491 LDRTKRQGASFIGILDMAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREG 550
Query: 1531 IEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTHNKHPKFIVP 1710
IEW FIDFGLDLQPTIDLI+KP G++ALLDEEC FPKA DK+FV+KL H+ HPKF+
Sbjct: 551 IEWKFIDFGLDLQPTIDLIDKPGGIMALLDEECWFPKATDKTFVDKLVSAHSMHPKFMKT 610
Query: 1711 DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGI 1890
D R + FA+VHYAGRVDYSA +WLMKNMDPLNEN+V L+Q S DPFV IWKDAE G+
Sbjct: 611 DFRGVADFAIVHYAGRVDYSAAKWLMKNMDPLNENIVSLLQGSQDPFVVNIWKDAEIVGM 670
Query: 1891 CAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKIN 2070
+ +T FG R+RKGMFRTVS L+KEQL KLM TLRNT+P+FVRCIIPNHEK++GKI+
Sbjct: 671 AQQALTDTQFGARTRKGMFRTVSHLYKEQLAKLMDTLRNTNPNFVRCIIPNHEKRAGKID 730
Query: 2071 SNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMI 2250
+ LVL+QLRCNGVLEGIRICRQGFPNR+PFQEFR RYE+LTP+VIPK F+DGK++ KMI
Sbjct: 731 APLVLDQLRCNGVLEGIRICRQGFPNRIPFQEFRQRYELLTPNVIPKGFMDGKKACEKMI 790
Query: 2251 TALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXX 2430
AL++D+NLYR+GQSK+FFR GVLAHLEEERD K++ LI+NFQA CRGFL+RR Y
Sbjct: 791 QALELDSNLYRVGQSKIFFRAGVLAHLEEERDFKISDLIVNFQAFCRGFLARRNYQKRLQ 850
Query: 2431 XXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKM 2610
N AYLKLRNWQWWRL+TKVKPLL+VT+ ++++ K+DEL+ +E+L +
Sbjct: 851 QLNAIRIIQRNCAAYLKLRNWQWWRLYTKVKPLLEVTKQEEKLVQKEDELKQVREKLDTL 910
Query: 2611 EHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRL 2790
+ +E E+K Q +VE+ + EQLQ E E AE ++ R RL R QELE ++ ++ R+
Sbjct: 911 AKNTQEYERKYQQALVEKTTLAEQLQAEIELCAEAEESRSRLMARKQELEDMMQELETRI 970
Query: 2791 SXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQ 2970
++K ++D +K +D
Sbjct: 971 EEEEERVLALGGEKKKLELNIQDLEEQLEEEEAARQKLQLEKVQLDAKIKKYEEDLALTD 1030
Query: 2971 DAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKS 3150
D L+ L + EE+AKH K K + E + ELE+ L++++Q +
Sbjct: 1031 DQNQKLLKEKKLLEERANDLSQTLAEEEEKAKHLAKLKAKHEATITELEERLHKDQQQRQ 1090
Query: 3151 ELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQK 3330
E ++ KRK+ E+ D K+ L E+ +V+E+ QL KR+EEL L R DEESA QK
Sbjct: 1091 ESDRSKRKIETEVADLKEQLNERRVQVDEMQAQLAKREEELTQTLLRIDEESATKATAQK 1150
Query: 3331 QMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSR 3510
R++++ + E++ED+E E+ AR KAE RR++ +LE +K ++LD +D Q+L S+
Sbjct: 1151 AQRELESQLAEIQEDLEAEKAARAKAEKVRRDLSEELEALKNELLDSLDTTAAQQELRSK 1210
Query: 3511 KDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQ 3690
+++E+ K+++E+ EG + + + K S+++ ++DQ+E +K ++ LEK + +
Sbjct: 1211 REQELATLKKSLEEETVNHEGVLADMRHKHSQELNSINDQLENLRKAKTVLEKAKGTLEA 1270
Query: 3691 ERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDH 3870
E AD+A E+ + +SR + D++RK E+ + E+Q LAE + + L ++ + + E ++
Sbjct: 1271 ENADLATELRSVNSSRQENDRRRKQAESQIAELQVKLAEIERARSELQEKCTKLQQEAEN 1330
Query: 3871 LNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDE 4050
+ EE E + + + TR K+ ++ RQ+E EK AL ++
Sbjct: 1331 ITNQLEEAELKASAAVKSASNMESQLTEAQQLLEEETRQKLGLSSKLRQIESEKEALQEQ 1390
Query: 4051 KEEAEGLRAHLEKEIHAARQGAGEARRKAEESVN--QQLEELRKKNLRDVEHLQKQLEES 4224
EE + + + E+++ E ++KAEE + ++LEE +K+ +D+E L++Q++E
Sbjct: 1391 LEEDDEAKRNYERKLAEVTTQMQEIKKKAEEDADLAKELEEGKKRLNKDIEALERQVKEL 1450
Query: 4225 EVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDR 4404
+R+ +SKKKIQ ELED+++ELE R + EK+QK F+ +AEE+ ++ +R
Sbjct: 1451 IAQNDRLDKSKKKIQSELEDATIELEAQRTKVLELEKKQKNFDKILAEEKAISEQIAQER 1510
Query: 4405 DAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELE 4584
D +E R++ET+VLS+ E+D + +E+ + R++LQ EL D + + KNVHELE
Sbjct: 1511 DTAEREAREKETKVLSVSRELDEAFDKIEDLENKRKTLQNELDDLANTQGTADKNVHELE 1570
Query: 4585 KAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKR 4764
KAKR+LE++L +++ Q EELED+LQ+ EDA+LRLEV QAL+S+ +R + K+ AEEKR
Sbjct: 1571 KAKRALESQLAELKAQNEELEDDLQLTEDAKLRLEVNMQALRSQFERDLLAKEEGAEEKR 1630
Query: 4765 RGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXX 4944
RGL+KQ+RDLE EL+ E++ ++ AV+ +KK+E + E+E +E+ N++KE+
Sbjct: 1631 RGLVKQLRDLETELDEERKQRTAAVASKKKLEGDLKEIETTMEMHNKVKEDALKHAKKLQ 1690
Query: 4945 XXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLRE---ANEGLMQARKQXXX 5115
+ + EEA+ AKE++ AL +EAD K +A+EAE QL E ++E +A +
Sbjct: 1691 AQVKDALRDAEEAKAAKEELQALSKEADGKVKALEAEVLQLTEDLASSERARRAAETERD 1750
Query: 5116 XXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITT 5295
A G + +EKRRLEA+IA QSN E+ +D+ RKAQ+Q+EQ+TT
Sbjct: 1751 ELAEEIANNANKGSLMIDEKRRLEARIATLEEELEEEQSNSEVLLDRSRKAQLQIEQLTT 1810
Query: 5296 DLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLN 5475
+L+ E++ +QK E + LER N++ KAK+ E+E+ +++ +A +A LEAK+ LE+QL
Sbjct: 1811 ELANEKSNSQKNENGRALLERQNKELKAKLAEIETAQRTKVKATIATLEAKIANLEEQLE 1870
Query: 5476 VEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAED 5655
EG+E+ +A R+++K++ + T EDE+R +Q KE ++K N + + L+R LDE E+
Sbjct: 1871 NEGKERLLQQKANRKMDKKIKELTMNIEDERRHVDQHKEQMDKLNSRIKLLKRNLDETEE 1930
Query: 5656 EMSRERTKHRNVQREADDLLDANEQLTREL 5745
E+ +E+T+ R QRE +D++++ E + RE+
Sbjct: 1931 ELQKEKTQKRKYQRECEDMIESQEAMNREI 1960
Score = 160 bits (405), Expect = 3e-37
Identities = 192/935 (20%), Positives = 386/935 (40%), Gaps = 55/935 (5%)
Frame = +1
Query: 2530 LQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSA 2709
+QV ++ +++EL T R+ + +K ++ + A IQE L+ E A
Sbjct: 1115 VQVDEMQAQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAEKAARA 1174
Query: 2710 ELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXX 2889
+ + +R L ++ELE + N++ D L R +++ T++
Sbjct: 1175 KAEKVRRDL---SEELEALKNELLDSLDTTAAQQELRSK-REQELATLKKSLEEETVNHE 1230
Query: 2890 XXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKH 3069
K + Q + A L T+L +
Sbjct: 1231 GVLADMRHKHS--QELNSINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQE 1288
Query: 3070 GVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQ 3249
+ + + E+Q+ EL+ L + +SEL++ KL E E+ + L E K
Sbjct: 1289 NDRRRKQAESQIAELQVKLAEIERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKS 1348
Query: 3250 LMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREV 3429
+ +L +EE+ + ++R +++ + L+E +E + A+ E EV
Sbjct: 1349 ASNMESQLTEAQQLLEEETRQKLGLSSKLRQIESEKEALQEQLEEDDEAKRNYERKLAEV 1408
Query: 3430 VAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQ 3609
Q++++K + D A L++ R ++++ A +R ++++ ++++ K K +
Sbjct: 1409 TTQMQEIKKKAEEDADLAKELEEGKKRLNKDIEALERQVKELI-AQNDRLDKSKKKIQSE 1467
Query: 3610 VEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEI 3789
+E+ ++E + + +LEK+Q D+ A+ + R +++ + E ++ +
Sbjct: 1468 LEDATIELEAQRTKVLELEKKQKNFDKILAEEKAISEQIAQERDTAEREAREKETKVLSV 1527
Query: 3790 QANLAESDEHKRTLIDQLERSRDELDHLNRVR---EEEEHAFANMQRRLATAXXXXXXXX 3960
L E+ + L ++ + ++ELD L + ++ H +R L +
Sbjct: 1528 SRELDEAFDKIEDLENKRKTLQNELDDLANTQGTADKNVHELEKAKRALESQLA------ 1581
Query: 3961 XXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAE 4140
LK N L+ ++A L + + LR+ E+++ A +GA E RR
Sbjct: 1582 -------ELKAQNEELEDDLQLTEDAKLRLEVNMQALRSQFERDLLAKEEGAEEKRRGLV 1634
Query: 4141 ESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASH 4320
K LRD+E +L+E + + SKKK++ +L++ +E
Sbjct: 1635 ------------KQLRDLE---TELDEERKQRTAAVASKKKLEGDLKEIETTMEMHNKVK 1679
Query: 4321 RDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESD 4500
D+ K KK ++Q+ + ++A ++ + ++ + +V +L EV + E L S+
Sbjct: 1680 EDALKHAKKLQAQVKDALRDAEEAKAAKEELQALSKEADGKVKALEAEVLQLTEDLASSE 1739
Query: 4501 RVRRSLQ---QELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAED 4671
R RR+ + EL + I+N + G + + KR LEA + + ++EE + N ++ D
Sbjct: 1740 RARRAAETERDELAEEIANNANKGSLMID---EKRRLEARIATLEEELEEEQSNSEVLLD 1796
Query: 4672 ----ARLRLEVTNQAL--------KSESDRAI---SNKDVEA-----EEKRRGLLK---- 4779
A+L++E L K+E+ RA+ NK+++A E +R +K
Sbjct: 1797 RSRKAQLQIEQLTTELANEKSNSQKNENGRALLERQNKELKAKLAEIETAQRTKVKATIA 1856
Query: 4780 ----QIRDLENELENEKRGKSGAVSHRKKIENQIGEL---------------EQQLEVAN 4902
+I +LE +LENE + + +K++ +I EL EQ ++ +
Sbjct: 1857 TLEAKIANLEEQLENEGKERLLQQKANRKMDKKIKELTMNIEDERRHVDQHKEQMDKLNS 1916
Query: 4903 RLK------EEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQ 5064
R+K +E +YQ ECE+ +++E + + K R
Sbjct: 1917 RIKLLKRNLDETEEELQKEKTQKRKYQRECEDMIESQEAMNREINSLKTKLR-------- 1968
Query: 5065 LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSE 5169
R GL +R RA GGG S +
Sbjct: 1969 -RTGGIGLSSSR-----LTGTPSSKRAGGGGGSDD 1997
>gi|1572481|gb|AAB09049.1| nonmuscle myosin-II heavy chain [Drosophila
melanogaster]
Length = 2057
Score = 1835 bits (4752), Expect = 0.0
Identities = 948/1950 (48%), Positives = 1323/1950 (67%), Gaps = 37/1950 (1%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRK-LCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQ 183
+L+YL V+R R L WVP +N+GF+ SIKRE DEV VEL +T ++
Sbjct: 56 ELKYLSVERNQFNPIRPRRPSGHRSVLVWVPHENQGFVAASIKREHGDEVEVELAETGKR 115
Query: 184 VTISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPY 363
V I RDD+QK NPPKFDK+EDM+ELT LNEASVLHN+KDRYYS LIYTYSGLFCVV+NPY
Sbjct: 116 VMILRDDIQKMNPPKFDKVEDMAELTCLNEASVLHNIKDRYYSGLIYTYSGLFCVVVNPY 175
Query: 364 KKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENT 543
KKLPIY+E ++E +KG KRHE+PPH+FAI D+AYR+ML +REDQSILCTGESGAGKTENT
Sbjct: 176 KKLPIYTEKIMERYKGIKRHEVPPHVFAITDSAYRNMLGDREDQSILCTGESGAGKTENT 235
Query: 544 KKVIQYLAHVAGATR-------------NKSLNA-------AAQQNIVQKPDVRNPI--- 654
KKVIQ+LA+VA + N S+N QN Q +V N +
Sbjct: 236 KKVIQFLAYVAASKPKGSGAVPHPAVLINFSVNTNKYIKVKIMAQNQNQTIEVVNGLKMV 295
Query: 655 --------GELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIEF 810
GELE QLLQANPILEAFGN+KTVKNDNSSRFGKFIRINFD SG+ISGANIE
Sbjct: 296 EVNSNCQEGELEQQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDASGFISGANIET 355
Query: 811 YLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRFLVNRGITLPNVDDV 990
YLLEKSR +RQA+DER+FHIFYQ+L G + +++ +++L+ V +Y FL N + +P VDD
Sbjct: 356 YLLEKSRAIRQAKDERTFHIFYQLLAGATPEQREKFILDDVKSYAFLSNGSLPVPGVDDY 415
Query: 991 QEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQKVCH 1170
EF +T+ SM IMG ++ +SI R+VSAVLL G+++F QE+ +DQA L D+ V QK+ H
Sbjct: 416 AEFQATVKSMNIMGMTSEDFNSIFRIVSAVLLFGSMKFRQERNNDQATLPDNTVAQKIAH 475
Query: 1171 LLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRINKS 1350
LLGL V ++ +AFL PRIKVGR+FV KAQ +EQ EFAVEAIAKA YER+FKWLV RIN+S
Sbjct: 476 LLGLSVTDMTRAFLTPRIKVGRDFVTKAQTKEQVEFAVEAIAKACYERMFKWLVNRINRS 535
Query: 1351 LDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQREG 1530
LDRT RQGASFIGILD+AGFEIF++NSFEQ+CINYTNEKLQQLFN+TMFILEQEEYQREG
Sbjct: 536 LDRTKRQGASFIGILDMAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREG 595
Query: 1531 IEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTHNKHPKFIVP 1710
IEW FIDFGLDLQPTIDLI+KP G++ALLDEEC FPKA DK+FV+KL H+ HPKF+
Sbjct: 596 IEWKFIDFGLDLQPTIDLIDKPGGIMALLDEECWFPKATDKTFVDKLVSAHSMHPKFMKT 655
Query: 1711 DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGI 1890
D R + FA+VHYAGRVDYSA +WLMKNMDPLNEN+V L+Q S DPFV IWKDAE G+
Sbjct: 656 DFRGVADFAIVHYAGRVDYSAAKWLMKNMDPLNENIVSLLQGSQDPFVVNIWKDAEIVGM 715
Query: 1891 CAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKIN 2070
+ +T FG R+RKGMFRTVS L+KEQL KLM TLRNT+P+FVRCIIPNHEK++GKI+
Sbjct: 716 AQQALTDTQFGARTRKGMFRTVSHLYKEQLAKLMDTLRNTNPNFVRCIIPNHEKRAGKID 775
Query: 2071 SNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMI 2250
+ LVL+QLRCNGVLEGIRICRQGFPNR+PFQEFR RYE+LTP+VIPK F+DGK++ KMI
Sbjct: 776 APLVLDQLRCNGVLEGIRICRQGFPNRIPFQEFRQRYELLTPNVIPKGFMDGKKACEKMI 835
Query: 2251 TALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXX 2430
AL++D+NLYR+GQSK+FFR GVLAHLEEERD K++ LI+NFQA CRGFL+RR Y
Sbjct: 836 QALELDSNLYRVGQSKIFFRAGVLAHLEEERDFKISDLIVNFQAFCRGFLARRNYQKRLQ 895
Query: 2431 XXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKM 2610
N AYLKLRNWQWWRL+TKVKPLL+VT+ ++++ K+DEL+ +E+L +
Sbjct: 896 QLNAIRIIQRNCAAYLKLRNWQWWRLYTKVKPLLEVTKQEEKLVQKEDELKQVREKLDTL 955
Query: 2611 EHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRL 2790
+ +E E+K Q +VE+ + EQLQ E E AE ++ R RL R QELE ++ ++ R+
Sbjct: 956 AKNTQEYERKYQQALVEKTTLAEQLQAEIELCAEAEESRSRLMARKQELEDMMQELETRI 1015
Query: 2791 SXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQ 2970
++K ++D +K +D
Sbjct: 1016 EEEEERVLALGGEKKKLELNIQDLEEQLEEEEAARQKLQLEKVQLDAKIKKYEEDLALTD 1075
Query: 2971 DAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKS 3150
D L+ L + EE+AKH K K + E + ELE+ L++++Q +
Sbjct: 1076 DQNQKLLKEKKLLEERANDLSQTLAEEEEKAKHLAKLKAKHEATITELEERLHKDQQQRQ 1135
Query: 3151 ELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQK 3330
E ++ KRK+ E+ D K+ L E+ +V+E+ QL KR+EEL L R DEESA QK
Sbjct: 1136 ESDRSKRKIETEVADLKEQLNERRVQVDEMQAQLAKREEELTQTLLRIDEESATKATAQK 1195
Query: 3331 QMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSR 3510
R++++ + E++ED+E E+ AR KAE RR++ +LE +K ++LD +D Q+L S+
Sbjct: 1196 AQRELESQLAEIQEDLEAEKAARAKAEKVRRDLSEELEALKNELLDSLDTTAAQQELRSK 1255
Query: 3511 KDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQ 3690
+++E+ K+++E+ EG + + + K S+++ ++DQ+E +K ++ LEK + +
Sbjct: 1256 REQELATLKKSLEEETVNHEGVLADMRHKHSQELNSINDQLENLRKAKTVLEKAKGTLEA 1315
Query: 3691 ERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDH 3870
E AD+A E+ + +SR + D++RK E+ + E+Q LAE + + L ++ + + E ++
Sbjct: 1316 ENADLATELRSVNSSRQENDRRRKQAESQIAELQVKLAEIERARSELQEKCTKLQQEAEN 1375
Query: 3871 LNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDE 4050
+ EE E + + + TR K+ ++ RQ+E EK AL ++
Sbjct: 1376 ITNQLEEAELKASAAVKSASNMESQLTEAQQLLEEETRQKLGLSSKLRQIESEKEALQEQ 1435
Query: 4051 KEEAEGLRAHLEKEIHAARQGAGEARRKAEESVN--QQLEELRKKNLRDVEHLQKQLEES 4224
EE + + + E+++ E ++KAEE + ++LEE +K+ +D+E L++Q++E
Sbjct: 1436 LEEDDEAKRNYERKLAEVTTQMQEIKKKAEEDADLAKELEEGKKRLNKDIEALERQVKEL 1495
Query: 4225 EVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDR 4404
+R+ +SKKKIQ ELED+++ELE R + EK+QK F+ +AEE+ ++ +R
Sbjct: 1496 IAQNDRLDKSKKKIQSELEDATIELEAQRTKVLELEKKQKNFDKILAEEKAISEQIAQER 1555
Query: 4405 DAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELE 4584
D +E R++ET+VLS+ E+D + +E+ + R++LQ EL D + + KNVHELE
Sbjct: 1556 DTAEREAREKETKVLSVSRELDEAFDKIEDLENKRKTLQNELDDLANTQGTADKNVHELE 1615
Query: 4585 KAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKR 4764
KAKR+LE++L +++ Q EELED+LQ+ EDA+LRLEV QAL+S+ +R + K+ AEEKR
Sbjct: 1616 KAKRALESQLAELKAQNEELEDDLQLTEDAKLRLEVNMQALRSQFERDLLAKEEGAEEKR 1675
Query: 4765 RGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXX 4944
RGL+KQ+RDLE EL+ E++ ++ AV+ +KK+E + E+E +E+ N++KE+
Sbjct: 1676 RGLVKQLRDLETELDEERKQRTAAVASKKKLEGDLKEIETTMEMHNKVKEDALKHAKKLQ 1735
Query: 4945 XXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLRE---ANEGLMQARKQXXX 5115
+ + EEA+ AKE++ AL +EAD K +A+EAE QL E ++E +A +
Sbjct: 1736 AQVKDALRDAEEAKAAKEELQALSKEADGKVKALEAEVLQLTEDLASSERARRAAETERD 1795
Query: 5116 XXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITT 5295
A G + +EKRRLEA+IA QSN E+ +D+ RKAQ+Q+EQ+TT
Sbjct: 1796 ELAEEIANNANKGSLMIDEKRRLEARIATLEEELEEEQSNSEVLLDRSRKAQLQIEQLTT 1855
Query: 5296 DLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLN 5475
+L+ E++ +QK E + LER N++ KAK+ E+E+ +++ +A +A LEAK+ LE+QL
Sbjct: 1856 ELANEKSNSQKNENGRALLERQNKELKAKLAEIETAQRTKVKATIATLEAKIANLEEQLE 1915
Query: 5476 VEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAED 5655
EG+E+ +A R+++K++ + T EDE+R +Q KE ++K N + + L+R LDE E+
Sbjct: 1916 NEGKERLLQQKANRKMDKKIKELTMNIEDERRHVDQHKEQMDKLNSRIKLLKRNLDETEE 1975
Query: 5656 EMSRERTKHRNVQREADDLLDANEQLTREL 5745
E+ +E+T+ R QRE +D++++ E + RE+
Sbjct: 1976 ELQKEKTQKRKYQRECEDMIESQEAMNREI 2005
Score = 160 bits (405), Expect = 3e-37
Identities = 192/935 (20%), Positives = 386/935 (40%), Gaps = 55/935 (5%)
Frame = +1
Query: 2530 LQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSA 2709
+QV ++ +++EL T R+ + +K ++ + A IQE L+ E A
Sbjct: 1160 VQVDEMQAQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAEKAARA 1219
Query: 2710 ELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXX 2889
+ + +R L ++ELE + N++ D L R +++ T++
Sbjct: 1220 KAEKVRRDL---SEELEALKNELLDSLDTTAAQQELRSK-REQELATLKKSLEEETVNHE 1275
Query: 2890 XXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKH 3069
K + Q + A L T+L +
Sbjct: 1276 GVLADMRHKHS--QELNSINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQE 1333
Query: 3070 GVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQ 3249
+ + + E+Q+ EL+ L + +SEL++ KL E E+ + L E K
Sbjct: 1334 NDRRRKQAESQIAELQVKLAEIERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKS 1393
Query: 3250 LMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREV 3429
+ +L +EE+ + ++R +++ + L+E +E + A+ E EV
Sbjct: 1394 ASNMESQLTEAQQLLEEETRQKLGLSSKLRQIESEKEALQEQLEEDDEAKRNYERKLAEV 1453
Query: 3430 VAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQ 3609
Q++++K + D A L++ R ++++ A +R ++++ ++++ K K +
Sbjct: 1454 TTQMQEIKKKAEEDADLAKELEEGKKRLNKDIEALERQVKELI-AQNDRLDKSKKKIQSE 1512
Query: 3610 VEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEI 3789
+E+ ++E + + +LEK+Q D+ A+ + R +++ + E ++ +
Sbjct: 1513 LEDATIELEAQRTKVLELEKKQKNFDKILAEEKAISEQIAQERDTAEREAREKETKVLSV 1572
Query: 3790 QANLAESDEHKRTLIDQLERSRDELDHLNRVR---EEEEHAFANMQRRLATAXXXXXXXX 3960
L E+ + L ++ + ++ELD L + ++ H +R L +
Sbjct: 1573 SRELDEAFDKIEDLENKRKTLQNELDDLANTQGTADKNVHELEKAKRALESQLA------ 1626
Query: 3961 XXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAE 4140
LK N L+ ++A L + + LR+ E+++ A +GA E RR
Sbjct: 1627 -------ELKAQNEELEDDLQLTEDAKLRLEVNMQALRSQFERDLLAKEEGAEEKRRGLV 1679
Query: 4141 ESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASH 4320
K LRD+E +L+E + + SKKK++ +L++ +E
Sbjct: 1680 ------------KQLRDLE---TELDEERKQRTAAVASKKKLEGDLKEIETTMEMHNKVK 1724
Query: 4321 RDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESD 4500
D+ K KK ++Q+ + ++A ++ + ++ + +V +L EV + E L S+
Sbjct: 1725 EDALKHAKKLQAQVKDALRDAEEAKAAKEELQALSKEADGKVKALEAEVLQLTEDLASSE 1784
Query: 4501 RVRRSLQ---QELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAED 4671
R RR+ + EL + I+N + G + + KR LEA + + ++EE + N ++ D
Sbjct: 1785 RARRAAETERDELAEEIANNANKGSLMID---EKRRLEARIATLEEELEEEQSNSEVLLD 1841
Query: 4672 ----ARLRLEVTNQAL--------KSESDRAI---SNKDVEA-----EEKRRGLLK---- 4779
A+L++E L K+E+ RA+ NK+++A E +R +K
Sbjct: 1842 RSRKAQLQIEQLTTELANEKSNSQKNENGRALLERQNKELKAKLAEIETAQRTKVKATIA 1901
Query: 4780 ----QIRDLENELENEKRGKSGAVSHRKKIENQIGEL---------------EQQLEVAN 4902
+I +LE +LENE + + +K++ +I EL EQ ++ +
Sbjct: 1902 TLEAKIANLEEQLENEGKERLLQQKANRKMDKKIKELTMNIEDERRHVDQHKEQMDKLNS 1961
Query: 4903 RLK------EEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQ 5064
R+K +E +YQ ECE+ +++E + + K R
Sbjct: 1962 RIKLLKRNLDETEEELQKEKTQKRKYQRECEDMIESQEAMNREINSLKTKLR-------- 2013
Query: 5065 LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSE 5169
R GL +R RA GGG S +
Sbjct: 2014 -RTGGIGLSSSR-----LTGTPSSKRAGGGGGSDD 2042
>gi|2119295|pir||S61477 myosin II heavy chain, non-muscle - fruit fly
(Drosophila melanogaster)
Length = 2057
Score = 1833 bits (4749), Expect = 0.0
Identities = 947/1950 (48%), Positives = 1323/1950 (67%), Gaps = 37/1950 (1%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRK-LCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQ 183
+L+YL V+R R L WVP +N+GF+ SIKRE DEV VEL +T ++
Sbjct: 56 ELKYLSVERNQFNPIRPRRPSGHRSVLVWVPHENQGFVAASIKREHGDEVEVELAETGKR 115
Query: 184 VTISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPY 363
V I RDD+QK NPPKFDK+EDM+ELT LNEASVLHN+KDRYYS LIYTYSGLFCVV+NPY
Sbjct: 116 VMILRDDIQKMNPPKFDKVEDMAELTCLNEASVLHNIKDRYYSGLIYTYSGLFCVVVNPY 175
Query: 364 KKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENT 543
KKLPIY+E ++E +KG KRHE+PPH+FAI D+AYR+ML +REDQSILCTGESGAGKTENT
Sbjct: 176 KKLPIYTEKIMERYKGIKRHEVPPHVFAITDSAYRNMLGDREDQSILCTGESGAGKTENT 235
Query: 544 KKVIQYLAHVAGATR-------------NKSLNA-------AAQQNIVQKPDVRNPI--- 654
KKVIQ+LA+VA + N S+N QN Q +V N +
Sbjct: 236 KKVIQFLAYVAASKPKGSGAVPHPAVLINFSVNTNKYIKVKIMAQNQNQTIEVVNGLKMV 295
Query: 655 --------GELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIEF 810
GELE QLLQANPILEAFGN+KTVKNDNSSRFGKFIRINFD SG+ISGANIE
Sbjct: 296 EVNSNCQEGELEQQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDASGFISGANIET 355
Query: 811 YLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRFLVNRGITLPNVDDV 990
YLLEKSR +RQA+DER+FHIFYQ+L G + +++ +++L+ V +Y FL N + +P VDD
Sbjct: 356 YLLEKSRAIRQAKDERTFHIFYQLLAGATPEQREKFILDDVKSYAFLSNGSLPVPGVDDY 415
Query: 991 QEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQKVCH 1170
EF +T+ SM IMG ++ +SI R+VSAVLL G+++F QE+ +DQA L D+ V QK+ H
Sbjct: 416 AEFQATVKSMNIMGMTSEDFNSIFRIVSAVLLFGSMKFRQERNNDQATLPDNTVAQKIAH 475
Query: 1171 LLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRINKS 1350
LLGL V ++ +AFL PRIKVGR+FV KAQ +EQ EFAVEAIAKA YER+FKWLV RIN+S
Sbjct: 476 LLGLSVTDMTRAFLTPRIKVGRDFVTKAQTKEQVEFAVEAIAKACYERMFKWLVNRINRS 535
Query: 1351 LDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQREG 1530
LDRT RQGASFIGILD+AGFEIF++NSFEQ+CINYTNEKLQQLFN+TMFILEQEEYQREG
Sbjct: 536 LDRTKRQGASFIGILDMAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREG 595
Query: 1531 IEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTHNKHPKFIVP 1710
IEW FIDFGLDLQPTIDLI+KP G++ALLDEEC FPKA DK+FV+KL H+ HPKF+
Sbjct: 596 IEWKFIDFGLDLQPTIDLIDKPGGIMALLDEECWFPKATDKTFVDKLVSAHSMHPKFMKT 655
Query: 1711 DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGI 1890
D R + FA+VHYAGRVDYSA +WLMKNMDPLNEN+V L+Q S DPFV IWKDAE G+
Sbjct: 656 DFRGVADFAIVHYAGRVDYSAAKWLMKNMDPLNENIVSLLQGSQDPFVVNIWKDAEIVGM 715
Query: 1891 CAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKIN 2070
+ +T FG R+RKGMFRTVS L+KEQL KLM TLRNT+P+FVRCIIPNHEK++GKI+
Sbjct: 716 AQQALTDTQFGARTRKGMFRTVSHLYKEQLAKLMDTLRNTNPNFVRCIIPNHEKRAGKID 775
Query: 2071 SNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMI 2250
+ LVL+QLRCNGVLEGIRICRQGFPNR+PFQEFR RYE+LTP+VIPK F+DGK++ KMI
Sbjct: 776 APLVLDQLRCNGVLEGIRICRQGFPNRIPFQEFRQRYELLTPNVIPKGFMDGKKACEKMI 835
Query: 2251 TALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXX 2430
AL++D+NLYR+GQSK+FFR GVLAHLEEERD K++ LI+NFQA CRGFL+RR Y
Sbjct: 836 QALELDSNLYRVGQSKIFFRAGVLAHLEEERDFKISDLIVNFQAFCRGFLARRNYQKRLQ 895
Query: 2431 XXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKM 2610
N AYLKLRNWQWWRL+TKVKPLL+VT+ ++++ K+DEL+ +E+L +
Sbjct: 896 QLNAIRIIQRNCAAYLKLRNWQWWRLYTKVKPLLEVTKQEEKLVQKEDELKQVREKLDTL 955
Query: 2611 EHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRL 2790
+ +E E+K Q +VE+ + EQLQ E E AE ++ R RL R QELE ++ ++ R+
Sbjct: 956 AKNTQEYERKYQQALVEKTTLAEQLQAEIELCAEAEESRSRLMARKQELEDMMQELETRI 1015
Query: 2791 SXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQ 2970
++K ++D +K +D
Sbjct: 1016 EEEEERVLALGGEKKKLELNIQDLEEQLEEEEAARQKLQLEKVQLDAKIKKYEEDLALTD 1075
Query: 2971 DAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKS 3150
D L+ L + EE+AKH K K + E + ELE+ L++++Q +
Sbjct: 1076 DQNQKLLKEKKLLEERANDLSQTLAEEEEKAKHLAKLKAKHEATITELEERLHKDQQQRQ 1135
Query: 3151 ELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQK 3330
E ++ KRK+ E+ D K+ L E+ +V+E+ QL KR+EEL L R DEESA QK
Sbjct: 1136 ESDRSKRKIETEVADLKEQLNERRVQVDEMQAQLAKREEELTQTLLRIDEESATKATAQK 1195
Query: 3331 QMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSR 3510
R++++ + E++ED+E E+ AR KAE RR++ +LE +K ++LD +D Q+L S+
Sbjct: 1196 AQRELESQLAEIQEDLEAEKAARAKAEKVRRDLSEELEALKNELLDSLDTTAAQQELRSK 1255
Query: 3511 KDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQ 3690
+++E+ K+++E+ EG + + + K S+++ ++DQ+E +K ++ LEK + +
Sbjct: 1256 REQELATLKKSLEEETVNHEGVLADMRHKHSQELNSINDQLENLRKAKTVLEKAKGTLEA 1315
Query: 3691 ERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDH 3870
E AD+A E+ + +SR + D++RK E+ + E+Q LAE + + L ++ + + E ++
Sbjct: 1316 ENADLATELRSVNSSRQENDRRRKQAESQIAELQVKLAEIERARSELQEKCTKLQQEAEN 1375
Query: 3871 LNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDE 4050
+ EE E + + + TR K+ ++ RQ+E EK AL ++
Sbjct: 1376 ITNQLEEAELKASAAVKSASNMESQLTEAQQLLEEETRQKLGLSSKLRQIESEKEALQEQ 1435
Query: 4051 KEEAEGLRAHLEKEIHAARQGAGEARRKAEESVN--QQLEELRKKNLRDVEHLQKQLEES 4224
EE + + + E+++ E ++KAEE + ++LEE +K+ +D+E L++Q++E
Sbjct: 1436 LEEDDEAKRNYERKLAEVTTQMQEIKKKAEEDADLAKELEEGKKRLNKDIEALERQVKEL 1495
Query: 4225 EVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDR 4404
+R+ +SKKKIQ ELED+++ELE R + EK+QK F+ +AEE+ ++ +R
Sbjct: 1496 IAQNDRLDKSKKKIQSELEDATIELEAQRTKVLELEKKQKNFDKILAEEKAISEQIAQER 1555
Query: 4405 DAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELE 4584
D +E R++ET+VLS+ E+D + +E+ + R++LQ EL D + + KNVHELE
Sbjct: 1556 DTAEREAREKETKVLSVSRELDEAFDKIEDLENKRKTLQNELDDLANTQGTADKNVHELE 1615
Query: 4585 KAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKR 4764
KAKR+LE++L +++ Q EELED+LQ+ EDA+LRLEV QAL+S+ +R + K+ AEEKR
Sbjct: 1616 KAKRALESQLAELKAQNEELEDDLQLTEDAKLRLEVNMQALRSQFERDLLAKEEGAEEKR 1675
Query: 4765 RGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXX 4944
RGL+KQ+RDLE EL+ E++ ++ AV+ +KK+E + E+E +E+ N++KE+
Sbjct: 1676 RGLVKQLRDLETELDEERKQRTAAVASKKKLEGDLKEIETTMEMHNKVKEDALKHAKKLQ 1735
Query: 4945 XXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLRE---ANEGLMQARKQXXX 5115
+ + EEA+ AKE++ AL +EAD K +A+EAE QL E ++E +A +
Sbjct: 1736 AQVKDALRDAEEAKAAKEELQALSKEADGKVKALEAEVLQLTEDLASSERARRAAETERD 1795
Query: 5116 XXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITT 5295
A G + +EKRRLEA+IA QSN E+ +D+ RKAQ+Q+EQ+TT
Sbjct: 1796 ELAEEIANNANKGSLMIDEKRRLEARIATLEEELEEEQSNSEVLLDRSRKAQLQIEQLTT 1855
Query: 5296 DLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLN 5475
+L+ E++ +QK E + LER N++ KAK+ E+E+ +++ +A +A LEAK+ +E+QL
Sbjct: 1856 ELANEKSNSQKNENGRALLERQNKELKAKLAEIETAQRTKVKATIATLEAKIAKVEEQLE 1915
Query: 5476 VEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAED 5655
EG+E+ +A R+++K++ + T EDE+R +Q KE ++K N + + L+R LDE E+
Sbjct: 1916 NEGKERLLQQKANRKMDKKIKELTMNIEDERRHVDQHKEQMDKLNSRIKLLKRNLDETEE 1975
Query: 5656 EMSRERTKHRNVQREADDLLDANEQLTREL 5745
E+ +E+T+ R QRE +D++++ E + RE+
Sbjct: 1976 ELQKEKTQKRKYQRECEDMIESQEAMNREI 2005
Score = 158 bits (400), Expect = 1e-36
Identities = 191/935 (20%), Positives = 385/935 (40%), Gaps = 55/935 (5%)
Frame = +1
Query: 2530 LQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSA 2709
+QV ++ +++EL T R+ + +K ++ + A IQE L+ E A
Sbjct: 1160 VQVDEMQAQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAEKAARA 1219
Query: 2710 ELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXX 2889
+ + +R L ++ELE + N++ D L R +++ T++
Sbjct: 1220 KAEKVRRDL---SEELEALKNELLDSLDTTAAQQELRSK-REQELATLKKSLEEETVNHE 1275
Query: 2890 XXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKH 3069
K + Q + A L T+L +
Sbjct: 1276 GVLADMRHKHS--QELNSINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQE 1333
Query: 3070 GVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQ 3249
+ + + E+Q+ EL+ L + +SEL++ KL E E+ + L E K
Sbjct: 1334 NDRRRKQAESQIAELQVKLAEIERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKS 1393
Query: 3250 LMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREV 3429
+ +L +EE+ + ++R +++ + L+E +E + A+ E EV
Sbjct: 1394 ASNMESQLTEAQQLLEEETRQKLGLSSKLRQIESEKEALQEQLEEDDEAKRNYERKLAEV 1453
Query: 3430 VAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQ 3609
Q++++K + D A L++ R ++++ A +R ++++ ++++ K K +
Sbjct: 1454 TTQMQEIKKKAEEDADLAKELEEGKKRLNKDIEALERQVKELI-AQNDRLDKSKKKIQSE 1512
Query: 3610 VEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEI 3789
+E+ ++E + + +LEK+Q D+ A+ + R +++ + E ++ +
Sbjct: 1513 LEDATIELEAQRTKVLELEKKQKNFDKILAEEKAISEQIAQERDTAEREAREKETKVLSV 1572
Query: 3790 QANLAESDEHKRTLIDQLERSRDELDHLNRVR---EEEEHAFANMQRRLATAXXXXXXXX 3960
L E+ + L ++ + ++ELD L + ++ H +R L +
Sbjct: 1573 SRELDEAFDKIEDLENKRKTLQNELDDLANTQGTADKNVHELEKAKRALESQLA------ 1626
Query: 3961 XXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAE 4140
LK N L+ ++A L + + LR+ E+++ A +GA E RR
Sbjct: 1627 -------ELKAQNEELEDDLQLTEDAKLRLEVNMQALRSQFERDLLAKEEGAEEKRRGLV 1679
Query: 4141 ESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASH 4320
K LRD+E +L+E + + SKKK++ +L++ +E
Sbjct: 1680 ------------KQLRDLE---TELDEERKQRTAAVASKKKLEGDLKEIETTMEMHNKVK 1724
Query: 4321 RDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESD 4500
D+ K KK ++Q+ + ++A ++ + ++ + +V +L EV + E L S+
Sbjct: 1725 EDALKHAKKLQAQVKDALRDAEEAKAAKEELQALSKEADGKVKALEAEVLQLTEDLASSE 1784
Query: 4501 RVRRSLQ---QELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAED 4671
R RR+ + EL + I+N + G + + KR LEA + + ++EE + N ++ D
Sbjct: 1785 RARRAAETERDELAEEIANNANKGSLMID---EKRRLEARIATLEEELEEEQSNSEVLLD 1841
Query: 4672 ----ARLRLEVTNQAL--------KSESDRAI---SNKDVEA-----EEKRRGLLK---- 4779
A+L++E L K+E+ RA+ NK+++A E +R +K
Sbjct: 1842 RSRKAQLQIEQLTTELANEKSNSQKNENGRALLERQNKELKAKLAEIETAQRTKVKATIA 1901
Query: 4780 ----QIRDLENELENEKRGKSGAVSHRKKIENQIGEL---------------EQQLEVAN 4902
+I +E +LENE + + +K++ +I EL EQ ++ +
Sbjct: 1902 TLEAKIAKVEEQLENEGKERLLQQKANRKMDKKIKELTMNIEDERRHVDQHKEQMDKLNS 1961
Query: 4903 RLK------EEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQ 5064
R+K +E +YQ ECE+ +++E + + K R
Sbjct: 1962 RIKLLKRNLDETEEELQKEKTQKRKYQRECEDMIESQEAMNREINSLKTKLR-------- 2013
Query: 5065 LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSE 5169
R GL +R RA GGG S +
Sbjct: 2014 -RTGGIGLSSSR-----LTGTPSSKRAGGGGGSDD 2042
>gi|212450|gb|AAA48986.1| nonmuscle myosin heavy chain
Length = 1986
Score = 1824 bits (4725), Expect = 0.0
Identities = 950/1927 (49%), Positives = 1323/1927 (68%), Gaps = 16/1927 (0%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL V RA + +PAT A W +KL W+P + GF SIK E DEVLVEL + ++ +
Sbjct: 12 RYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVLVELAENGKKALV 71
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDM+ELT LNEASVLHNLKDRYYS LIYTYSGLFCVVINPYK L
Sbjct: 72 NKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNL 131
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYSE++IE ++GKKRHEMPPHI+AI+++AYR MLQ+REDQSILCTGESGAGKTENTKKV
Sbjct: 132 PIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKV 191
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPI---GELEHQLLQANPILEAFGNSKTV 723
IQYLAHVA + + + NI P+ P+ GELE QLLQANPILE+FGN+KTV
Sbjct: 192 IQYLAHVASSHKGRK-----DHNI--PPESPKPVKHQGELERQLLQANPILESFGNAKTV 244
Query: 724 KNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAK 903
KNDNSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFYQ+L G
Sbjct: 245 KNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLAGAGEH 304
Query: 904 EKSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVL 1083
KS+ LLEG +NYRFL N I +P D F T+ +M IMGF+ DEI S+++VVS+VL
Sbjct: 305 LKSDLLLEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHDEILSMLKVVSSVL 364
Query: 1084 LLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQ 1263
GN+ F +E+ +DQA + ++ V QK+CHLLG+ V+E +A L PRIKVGR++V KAQ +
Sbjct: 365 QFGNISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTK 424
Query: 1264 EQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQI 1443
EQA+FAVEA+AKA+YERLF+WLV RINK+LDRT RQGASFIGILDIAGFEIF++NSFEQ+
Sbjct: 425 EQADFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQL 484
Query: 1444 CINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLAL 1614
CINYTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP IDLIE+P GVLAL
Sbjct: 485 CINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLAL 544
Query: 1615 LDEECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMK 1791
LDEEC FPKA DK+FVEKL + H KF P ++ K+ F ++HYAG+VDY AD+WLMK
Sbjct: 545 LDEECWFPKATDKTFVEKLVQEQGTHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMK 604
Query: 1792 NMDPLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAFG--MRSRKGMFRTVS 1959
NMDPLN+NV L+ S+D FVA +WKD + G+ + ETAFG +++KGMFRTV
Sbjct: 605 NMDPLNDNVATLLHQSSDKFVAELWKDVDRIVGLDQVTGITETAFGSAYKTKKGMFRTVG 664
Query: 1960 QLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQG 2139
QL+KE LTKLM TLRNT+P+FVRCIIPNHEK++GK++ +LVL+QLRCNGVLEGIRICRQG
Sbjct: 665 QLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQG 724
Query: 2140 FPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGV 2319
FPNR+ FQEFR RYEILTP+ IPK F+DGK++ +MI AL++D NLYRIGQSK+FFR GV
Sbjct: 725 FPNRIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGV 784
Query: 2320 LAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQW 2499
LAHLEEERDLK+T +I+ FQA CRG+L+R+ + N AYLKLR+WQW
Sbjct: 785 LAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKILQRNCAAYLKLRHWQW 844
Query: 2500 WRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQE 2679
WR+FTKVKPLLQVTR ++E++AKD+EL KE+ K+E + E E+K Q++ E+ ++ E
Sbjct: 845 WRVFTKVKPLLQVTRQEEELQAKDEELMKVKEKQTKVEAELEEMERKHQQLLEEKNILAE 904
Query: 2680 QLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRD 2859
QLQ E+E AE +++R RL + QELE I++D+ R+ ++K ++D
Sbjct: 905 QLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQGHIQD 964
Query: 2860 XXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQ 3039
+K + +D T+Q
Sbjct: 965 LEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFLKEKKLMEDRIAECTSQ 1024
Query: 3040 LLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEK 3219
L + EE+AK+ K K + E + +LE+ L +E + + ELE+ KRKL E D +D +AE
Sbjct: 1025 LAEEEEKAKNLAKLKNKQEMMITDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAEL 1084
Query: 3220 MGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNAR 3399
++EEL QL K++EELQ L R DEE+ K +R++Q I EL+ED+E+E+ +R
Sbjct: 1085 QAQIEELKIQLAKKEEELQAALARGDEEAVQKNNALKVIRELQAQIAELQEDLESEKASR 1144
Query: 3400 NKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKI 3579
NKAE +R++ +LE +K ++ D +D Q+L +++++EV K+AIE+ E +I
Sbjct: 1145 NKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKAIEEETKNHEAQI 1204
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKR 3759
+E + + + +EEL +Q+EQ K+ ++ LEK + + + ++A E+ +LQ +A+ + KR
Sbjct: 1205 QEIRQRHATALEELSEQLEQAKRFKANLEKNKQGLESDNKELACEVKVLQQVKAESEHKR 1264
Query: 3760 KIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAX 3939
K +A + E+ A + E + + L ++ + ++ELD+++ + EE E + A+
Sbjct: 1265 KKLDAQVQELTAKVTEGERLRVELAEKANKLQNELDNVSSLLEEAEKKGIKFAKDAASLE 1324
Query: 3940 XXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAG 4119
TR K+ +R RQLE+EKN L +++EE E R +LEK++ A +
Sbjct: 1325 SQLQDTQELLQEETRQKLNLSSRIRQLEEEKNNLQEQQEEEEEARKNLEKQMLALQAQLA 1384
Query: 4120 EARRKAEESVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSM 4293
EA++K ++ + + LEE +KK L+D+E L ++LEE +A +++ ++K ++QQEL+D +
Sbjct: 1385 EAKKKVDDDLGTIEGLEENKKKLLKDMESLSQRLEEKAMAYDKLEKTKNRLQQELDDLMV 1444
Query: 4294 ELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDI 4473
+L++ R + EK+QKKF+ +AEE+ + +RD E R++ET+ LSL ++
Sbjct: 1445 DLDHQRQIVSNLEKKQKKFDQMLAEEKNISARYAEERDRAEAEAREKETKALSLARALEE 1504
Query: 4474 MKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDN 4653
E EE +R + L+ +++D +S+KDD GKNVHELEK+KR+LE ++ +MR Q+EELED
Sbjct: 1505 ALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRTLEQQVEEMRTQLEELEDE 1564
Query: 4654 LQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSG 4833
LQ EDA+LRLEV QA+K++ +R + +D + EEK+R L+KQ+R+LE ELE+E++ ++
Sbjct: 1565 LQATEDAKLRLEVNMQAMKAQFERDLQARDEQNEEKKRMLVKQVRELEAELEDERKQRAL 1624
Query: 4834 AVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAAL 5013
AV+ +KK+E + +LE Q+E AN+ ++E +YQ E EEAR ++++I A
Sbjct: 1625 AVAAKKKMEMDLKDLEGQIEAANKARDEAIKQLRKLQAQMKDYQRELEEARASRDEIFAQ 1684
Query: 5014 LREADRKFRAVEAEREQLRE---ANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRL 5184
+E+++K + +EAE QL+E A+E + +Q A G +EKRRL
Sbjct: 1685 SKESEKKLKGLEAEILQLQEEFAASERARRHAEQERDELADEIANSASGKSALLDEKRRL 1744
Query: 5185 EAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSN 5364
EA+IAQ QSN EL ++ RK +Q++ + ++L+ ER+ QK+E +Q LER N
Sbjct: 1745 EARIAQLEEELEEEQSNMELLNERFRKTTLQVDTLNSELAGERSAAQKSENARQQLERQN 1804
Query: 5365 RDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDT 5544
++ KAK+ ELE +S+ +A ++ LEAK+ LE+QL E +E+ AAN+ RR EK+L +
Sbjct: 1805 KELKAKLQELEGSVKSKFKATISTLEAKIAQLEEQLEQEAKERAAANKLVRRTEKKLKEV 1864
Query: 5545 TQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDAN 5724
Q EDE+R +Q KE +EK+N + + L+RQL+EAE+E +R R +QRE DD +AN
Sbjct: 1865 FMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEAN 1924
Query: 5725 EQLTREL 5745
E L+RE+
Sbjct: 1925 EGLSREV 1931
Score = 87.0 bits (214), Expect = 5e-15
Identities = 121/562 (21%), Positives = 234/562 (41%), Gaps = 27/562 (4%)
Frame = +1
Query: 4147 VNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRD 4326
V +Q EEL+ K+ E L K E+ + + + ++K QQ LE+ ++ E ++A
Sbjct: 857 VTRQEEELQAKD----EELMKVKEKQTKVEAELEEMERKHQQLLEEKNILAEQLQA---- 908
Query: 4327 SEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRV 4506
+ + E++ R+A +K L+ + L D E+RV EE +
Sbjct: 909 --ETELFAEAEEMRARLAAKKQELE-----EILHDLESRV--------------EEEEER 947
Query: 4507 RRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRL 4686
+ LQ E + + D + + E E A++ L+ E +++++E+ + + ED +
Sbjct: 948 NQILQNEKKKMQGHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKF 1007
Query: 4687 EVTNQALKSESDRAISNKDVEAEEKRRGLLK-------QIRDLENELENEKRGKSGAVSH 4845
+ + L + +++ E EEK + L K I DLE L+ E++ +
Sbjct: 1008 -LKEKKLMEDRIAECTSQLAEEEEKAKNLAKLKNKQEMMITDLEERLKKEEKTRQELEKA 1066
Query: 4846 RKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLR-- 5019
++K++ + +L+ Q+ EE ++ + A++ +E AAL R
Sbjct: 1067 KRKLDGETTDLQDQIAELQAQIEE----------------LKIQLAKKEEELQAALARGD 1110
Query: 5020 -EADRKFRAVEAERE---QLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLE 5187
EA +K A++ RE Q+ E E L + + + +E + L+
Sbjct: 1111 EEAVQKNNALKVIRELQAQIAELQEDLESEKASRNKAEKQKRDLSEELEALKTELEDTLD 1170
Query: 5188 AKIAQXXXXXXXXQSNCEL--AIDKQRK---AQVQ---------LEQITTDLSMERTLNQ 5325
AQ Q EL AI+++ K AQ+Q LE+++ L +
Sbjct: 1171 TTAAQQELRTKREQEVAELKKAIEEETKNHEAQIQEIRQRHATALEELSEQLEQAKRFKA 1230
Query: 5326 KTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAAN 5505
E KQ LE N++ ++ L+ ++A+ ++ +L+ + QE TA
Sbjct: 1231 NLEKNKQGLESDNKELACEVKVLQQ------------VKAESEHKRKKLDAQVQELTAKV 1278
Query: 5506 RAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHR 5685
RL L + +AN+ EL S+L L+EAE + +
Sbjct: 1279 TEGERLRVELAE---------KANKLQNELDNVSSL--------LEEAEKKGIKFAKDAA 1321
Query: 5686 NVQREADDLLDANEQLTRELMN 5751
+++ + D + ++ TR+ +N
Sbjct: 1322 SLESQLQDTQELLQEETRQKLN 1343
>gi|212449|gb|AAA48985.1| nonmuscle myosin heavy chain
Length = 1976
Score = 1821 bits (4716), Expect = 0.0
Identities = 947/1924 (49%), Positives = 1319/1924 (68%), Gaps = 13/1924 (0%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL V RA + +PAT A W +KL W+P + GF SIK E DEVLVEL + ++ +
Sbjct: 12 RYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVLVELAENGKKALV 71
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDM+ELT LNEASVLHNLKDRYYS LIYTYSGLFCVVINPYK L
Sbjct: 72 NKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNL 131
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYSE++IE ++GKKRHEMPPHI+AI+++AYR MLQ+REDQSILCTGESGAGKTENTKKV
Sbjct: 132 PIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKV 191
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
IQYLAHVA + + + + N GELE QLLQANPILE+FGN+KTVKND
Sbjct: 192 IQYLAHVASSHKGRKDH--------------NIPGELERQLLQANPILESFGNAKTVKND 237
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFYQ+L G KS
Sbjct: 238 NSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLAGAGEHLKS 297
Query: 913 EYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 1092
+ LLEG +NYRFL N I +P D F T+ +M IMGF+ DEI S+++VVS+VL G
Sbjct: 298 DLLLEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHDEILSMLKVVSSVLQFG 357
Query: 1093 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA 1272
N+ F +E+ +DQA + ++ V QK+CHLLG+ V+E +A L PRIKVGR++V KAQ +EQA
Sbjct: 358 NISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQA 417
Query: 1273 EFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICIN 1452
+FAVEA+AKA+YERLF+WLV RINK+LDRT RQGASFIGILDIAGFEIF++NSFEQ+CIN
Sbjct: 418 DFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCIN 477
Query: 1453 YTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDE 1623
YTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP IDLIE+P GVLALLDE
Sbjct: 478 YTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDE 537
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMD 1800
EC FPKA DK+FVEKL + H KF P ++ K+ F ++HYAG+VDY AD+WLMKNMD
Sbjct: 538 ECWFPKATDKTFVEKLVQEQGTHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMD 597
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAFG--MRSRKGMFRTVSQLH 1968
PLN+NV L+ S+D FVA +WKD + G+ + ETAFG +++KGMFRTV QL+
Sbjct: 598 PLNDNVATLLHQSSDKFVAELWKDVDRIVGLDQVTGITETAFGSAYKTKKGMFRTVGQLY 657
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
KE LTKLM TLRNT+P+FVRCIIPNHEK++GK++ +LVL+QLRCNGVLEGIRICRQGFPN
Sbjct: 658 KESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPN 717
Query: 2149 RVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAH 2328
R+ FQEFR RYEILTP+ IPK F+DGK++ +MI AL++D NLYRIGQSK+FFR GVLAH
Sbjct: 718 RIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAH 777
Query: 2329 LEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRL 2508
LEEERDLK+T +I+ FQA CRG+L+R+ + N AYLKLR+WQWWR+
Sbjct: 778 LEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKILQRNCAAYLKLRHWQWWRV 837
Query: 2509 FTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQ 2688
FTKVKPLLQVTR ++E++AKD+EL KE+ K+E + E E+K Q++ E+ ++ EQLQ
Sbjct: 838 FTKVKPLLQVTRQEEELQAKDEELMKVKEKQTKVEAELEEMERKHQQLLEEKNILAEQLQ 897
Query: 2689 QESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXX 2868
E+E AE +++R RL + QELE I++D+ R+ ++K ++D
Sbjct: 898 AETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQGHIQDLEE 957
Query: 2869 XXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLD 3048
+K + +D T+QL +
Sbjct: 958 QLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFLKEKKLMEDRIAECTSQLAE 1017
Query: 3049 HEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGK 3228
EE+AK+ K K + E + +LE+ L +E + + ELE+ KRKL E D +D +AE +
Sbjct: 1018 EEEKAKNLAKLKNKQEMMITDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQ 1077
Query: 3229 VEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKA 3408
+EEL QL K++EELQ L R DEE+ K +R++Q I EL+ED+E+E+ +RNKA
Sbjct: 1078 IEELKIQLAKKEEELQAALARGDEEAVQKNNALKVIRELQAQIAELQEDLESEKASRNKA 1137
Query: 3409 EMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQ 3588
E +R++ +LE +K ++ D +D Q+L +++++EV K+AIE+ E +I+E
Sbjct: 1138 EKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKAIEEETKNHEAQIQEI 1197
Query: 3589 KAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIH 3768
+ + + +EEL +Q+EQ K+ ++ LEK + + + ++A E+ +LQ +A+ + KRK
Sbjct: 1198 RQRHATALEELSEQLEQAKRFKANLEKNKQGLESDNKELACEVKVLQQVKAESEHKRKKL 1257
Query: 3769 EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXX 3948
+A + E+ A + E + + L ++ + ++ELD+++ + EE E + A+
Sbjct: 1258 DAQVQELTAKVTEGERLRVELAEKANKLQNELDNVSSLLEEAEKKGIKFAKDAASLESQL 1317
Query: 3949 XXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEAR 4128
TR K+ +R RQLE+EKN L +++EE E R +LEK++ A + EA+
Sbjct: 1318 QDTQELLQEETRQKLNLSSRIRQLEEEKNNLQEQQEEEEEARKNLEKQMLALQAQLAEAK 1377
Query: 4129 RKAEESVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
+K ++ + + LEE +KK L+D+E L ++LEE +A +++ ++K ++QQEL+D ++L+
Sbjct: 1378 KKVDDDLGTIEGLEENKKKLLKDMESLSQRLEEKAMAYDKLEKTKNRLQQELDDLMVDLD 1437
Query: 4303 NVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKE 4482
+ R + EK+QKKF+ +AEE+ + +RD E R++ET+ LSL ++ E
Sbjct: 1438 HQRQIVSNLEKKQKKFDQMLAEEKNISARYAEERDRAEAEAREKETKALSLARALEEALE 1497
Query: 4483 HLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQI 4662
EE +R + L+ +++D +S+KDD GKNVHELEK+KR+LE ++ +MR Q+EELED LQ
Sbjct: 1498 AKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRTLEQQVEEMRTQLEELEDELQA 1557
Query: 4663 AEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVS 4842
EDA+LRLEV QA+K++ +R + +D + EEK+R L+KQ+R+LE ELE+E++ ++ AV+
Sbjct: 1558 TEDAKLRLEVNMQAMKAQFERDLQARDEQNEEKKRMLVKQVRELEAELEDERKQRALAVA 1617
Query: 4843 HRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLRE 5022
+KK+E + +LE Q+E AN+ ++E +YQ E EEAR ++++I A +E
Sbjct: 1618 AKKKMEMDLKDLEGQIEAANKARDEAIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKE 1677
Query: 5023 ADRKFRAVEAEREQLRE---ANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAK 5193
+++K + +EAE QL+E A+E + +Q A G +EKRRLEA+
Sbjct: 1678 SEKKLKGLEAEILQLQEEFAASERARRHAEQERDELADEIANSASGKSALLDEKRRLEAR 1737
Query: 5194 IAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDY 5373
IAQ QSN EL ++ RK +Q++ + ++L+ ER+ QK+E +Q LER N++
Sbjct: 1738 IAQLEEELEEEQSNMELLNERFRKTTLQVDTLNSELAGERSAAQKSENARQQLERQNKEL 1797
Query: 5374 KAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQ 5553
KAK+ ELE +S+ +A ++ LEAK+ LE+QL E +E+ AAN+ RR EK+L + Q
Sbjct: 1798 KAKLQELEGSVKSKFKATISTLEAKIAQLEEQLEQEAKERAAANKLVRRTEKKLKEVFMQ 1857
Query: 5554 FEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQL 5733
EDE+R +Q KE +EK+N + + L+RQL+EAE+E +R R +QRE DD +ANE L
Sbjct: 1858 VEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGL 1917
Query: 5734 TREL 5745
+RE+
Sbjct: 1918 SREV 1921
Score = 87.0 bits (214), Expect = 5e-15
Identities = 121/562 (21%), Positives = 234/562 (41%), Gaps = 27/562 (4%)
Frame = +1
Query: 4147 VNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRD 4326
V +Q EEL+ K+ E L K E+ + + + ++K QQ LE+ ++ E ++A
Sbjct: 847 VTRQEEELQAKD----EELMKVKEKQTKVEAELEEMERKHQQLLEEKNILAEQLQA---- 898
Query: 4327 SEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRV 4506
+ + E++ R+A +K L+ + L D E+RV EE +
Sbjct: 899 --ETELFAEAEEMRARLAAKKQELE-----EILHDLESRV--------------EEEEER 937
Query: 4507 RRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRL 4686
+ LQ E + + D + + E E A++ L+ E +++++E+ + + ED +
Sbjct: 938 NQILQNEKKKMQGHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKF 997
Query: 4687 EVTNQALKSESDRAISNKDVEAEEKRRGLLK-------QIRDLENELENEKRGKSGAVSH 4845
+ + L + +++ E EEK + L K I DLE L+ E++ +
Sbjct: 998 -LKEKKLMEDRIAECTSQLAEEEEKAKNLAKLKNKQEMMITDLEERLKKEEKTRQELEKA 1056
Query: 4846 RKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLR-- 5019
++K++ + +L+ Q+ EE ++ + A++ +E AAL R
Sbjct: 1057 KRKLDGETTDLQDQIAELQAQIEE----------------LKIQLAKKEEELQAALARGD 1100
Query: 5020 -EADRKFRAVEAERE---QLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLE 5187
EA +K A++ RE Q+ E E L + + + +E + L+
Sbjct: 1101 EEAVQKNNALKVIRELQAQIAELQEDLESEKASRNKAEKQKRDLSEELEALKTELEDTLD 1160
Query: 5188 AKIAQXXXXXXXXQSNCEL--AIDKQRK---AQVQ---------LEQITTDLSMERTLNQ 5325
AQ Q EL AI+++ K AQ+Q LE+++ L +
Sbjct: 1161 TTAAQQELRTKREQEVAELKKAIEEETKNHEAQIQEIRQRHATALEELSEQLEQAKRFKA 1220
Query: 5326 KTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAAN 5505
E KQ LE N++ ++ L+ ++A+ ++ +L+ + QE TA
Sbjct: 1221 NLEKNKQGLESDNKELACEVKVLQQ------------VKAESEHKRKKLDAQVQELTAKV 1268
Query: 5506 RAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHR 5685
RL L + +AN+ EL S+L L+EAE + +
Sbjct: 1269 TEGERLRVELAE---------KANKLQNELDNVSSL--------LEEAEKKGIKFAKDAA 1311
Query: 5686 NVQREADDLLDANEQLTRELMN 5751
+++ + D + ++ TR+ +N
Sbjct: 1312 SLESQLQDTQELLQEETRQKLN 1333
>gi|33598964|ref|NP_780469.1| myosin heavy chain 10, non-muscle;
nonmuscle myosin heavy chain II-B; myosin IIB; myosin
heavy chain, nonmuscular, type B; nonmuscle myosin heavy
chain IIB [Mus musculus]
Length = 1976
Score = 1820 bits (4714), Expect = 0.0
Identities = 944/1924 (49%), Positives = 1319/1924 (68%), Gaps = 13/1924 (0%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL V RA + +PAT A W +KL W+P + GF SIK E DEV+VEL + ++ +
Sbjct: 12 RYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMV 71
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDM+ELT LNEASVLHNLKDRYYS LIYTYSGLFCVVINPYK L
Sbjct: 72 NKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNL 131
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYSE++IE ++GKKRHEMPPHI+AI+++AYR MLQ+REDQSILCTGESGAGKTENTKKV
Sbjct: 132 PIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKV 191
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
IQYLAHVA + + + + N GELE QLLQANPILE+FGN+KTVKND
Sbjct: 192 IQYLAHVASSHKGRKDH--------------NIPGELERQLLQANPILESFGNAKTVKND 237
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFYQ+L G KS
Sbjct: 238 NSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKS 297
Query: 913 EYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 1092
+ LLEG +NYRFL N I +P D F T+ +M IMGF+ +EI S+++VVS+VL G
Sbjct: 298 DLLLEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFG 357
Query: 1093 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA 1272
N+ F +E+ +DQA + ++ V QK+CHLLG+ V+E +A L PRIKVGR++V KAQ +EQA
Sbjct: 358 NISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQA 417
Query: 1273 EFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICIN 1452
+FAVEA+AKA+YERLF+WLV RINK+LDRT RQGASFIGILDIAGFEIF++NSFEQ+CIN
Sbjct: 418 DFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCIN 477
Query: 1453 YTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDE 1623
YTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP IDLIE+P GVLALLDE
Sbjct: 478 YTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDE 537
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMD 1800
EC FPKA DK+FVEKL + H KF P ++ K+ F ++HYAG+VDY AD+WLMKNMD
Sbjct: 538 ECWFPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMD 597
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAFG--MRSRKGMFRTVSQLH 1968
PLN+NV L+ S+D FVA +WKD + G+ M ETAFG +++KGMFRTV QL+
Sbjct: 598 PLNDNVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLY 657
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
KE LTKLM TLRNT+P+FVRCIIPNHEK++GK++ +LVL+QLRCNGVLEGIRICRQGFPN
Sbjct: 658 KESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPN 717
Query: 2149 RVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAH 2328
R+ FQEFR RYEILTP+ IPK F+DGK++ +MI AL++D NLYRIGQSK+FFR GVLAH
Sbjct: 718 RIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAH 777
Query: 2329 LEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRL 2508
LEEERDLK+T +I+ FQA CRG+L+R+ + N AYLKLR+WQWWR+
Sbjct: 778 LEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRV 837
Query: 2509 FTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQ 2688
FTKVKPLLQVTR ++E++AKD+EL KE+ K+E + E E+K Q++ E+ ++ EQLQ
Sbjct: 838 FTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQ 897
Query: 2689 QESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXX 2868
E+E AE +++R RL + QELE I++D+ R+ ++K ++D
Sbjct: 898 AETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEE 957
Query: 2869 XXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLD 3048
+K + +D ++QL +
Sbjct: 958 QLDEEEGARQKLQLEKVTAEAKIKKMEEEVLLLEDQNSKFIKEKKLMEDRIAECSSQLAE 1017
Query: 3049 HEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGK 3228
EE+AK+ K + + E + +LE+ L +E + + ELE+ KRKL E D +D +AE +
Sbjct: 1018 EEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQ 1077
Query: 3229 VEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKA 3408
V+EL QL K++EELQ L R D+E+ + K R++Q I EL+ED E+E+ +RNKA
Sbjct: 1078 VDELKVQLTKKEEELQGALARGDDETLHKNNALKVARELQAQIAELQEDFESEKASRNKA 1137
Query: 3409 EMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQ 3588
E +R++ +LE +K ++ D +D Q+L +++++EV K+A+E E +I++
Sbjct: 1138 EKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEDETKNHEAQIQDM 1197
Query: 3589 KAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIH 3768
+ + + +EEL +Q+EQ K+ ++ LEK + + + ++A E+ +LQ +A+ + KRK
Sbjct: 1198 RQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKL 1257
Query: 3769 EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXX 3948
+A + E+ A ++E D + L ++ + ++ELD+++ + EE E + A
Sbjct: 1258 DAQVQELHAKVSEGDRLRVELAEKANKLQNELDNVSTLLEEAEKKGIKFAKDAAGLESQL 1317
Query: 3949 XXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEAR 4128
TR K+ +R RQLE+EKN+L +++EE E R +LEK++ A + + +
Sbjct: 1318 QDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTK 1377
Query: 4129 RKAEESVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
+K ++ + + LEE +KK L+DVE L ++LEE +A +++ ++K ++QQEL+D +++L+
Sbjct: 1378 KKVDDDLGTIESLEEAKKKLLKDVEALSQRLEEKVLAYDKLEKTKNRLQQELDDLTVDLD 1437
Query: 4303 NVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKE 4482
+ R + EK+QKKF+ +AEE+ + +RD E R++ET+ LSL ++ E
Sbjct: 1438 HQRQIVSNLEKKQKKFDQLLAEEKGISARYAEERDRAEAEAREKETKALSLARALEEALE 1497
Query: 4483 HLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQI 4662
EE +R + L+ +++D +S+KDD GKNVHELEK+KR+LE ++ +MR Q+EELED LQ
Sbjct: 1498 AKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQA 1557
Query: 4663 AEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVS 4842
EDA+LRLEV QA+K++ +R + +D + EEK+R LLKQ+R+LE ELE+E++ ++ AV+
Sbjct: 1558 TEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLLKQVRELEAELEDERKQRALAVA 1617
Query: 4843 HRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLRE 5022
+KK+E + +LE Q+E AN+ ++E +YQ E EEAR ++++I A +E
Sbjct: 1618 SKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKE 1677
Query: 5023 ADRKFRAVEAEREQLREANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAK 5193
+++K +++EAE QL+E +AR+ Q A G +EKRRLEA+
Sbjct: 1678 SEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEIANSASGKSALLDEKRRLEAR 1737
Query: 5194 IAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDY 5373
IAQ QSN EL D+ RK +Q++ + T+L+ ER+ QK++ +Q LER N++
Sbjct: 1738 IAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNTELAAERSAAQKSDNARQQLERQNKEL 1797
Query: 5374 KAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQ 5553
KAK+ ELE +S+ +A ++ALEAK+ LE+QL E +E+ AAN+ RR EK+L + Q
Sbjct: 1798 KAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQ 1857
Query: 5554 FEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQL 5733
EDE+R +Q KE +EK+N + + L+RQL+EAE+E +R R +QRE DD +ANE L
Sbjct: 1858 VEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGL 1917
Query: 5734 TREL 5745
+RE+
Sbjct: 1918 SREV 1921
Score = 83.2 bits (204), Expect = 7e-14
Identities = 117/608 (19%), Positives = 242/608 (39%), Gaps = 46/608 (7%)
Frame = +1
Query: 4066 GLRAHLEKE---------IHAARQGAGEARRKAEESVNQQLEELR--KKN---------- 4182
G+ AHLE+E I G RKA QQL L+ ++N
Sbjct: 773 GVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHW 832
Query: 4183 --------LRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKR 4338
++ + + +Q EE + E +L+ K+K Q ++E E+E K
Sbjct: 833 QWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEK-QTKVEGELEEMER---------KH 882
Query: 4339 QKKFESQ--MAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRR 4512
Q+ E + +AE+ A + + + M L ++ + +L++++ E EE +++ +
Sbjct: 883 QQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQ 942
Query: 4513 SLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEV 4692
+ ++++Q I D + + E E A++ L+ E +++++E+ + + ED + +
Sbjct: 943 NEKKKMQAHIQ---DLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEVLLLEDQNSKF-I 998
Query: 4693 TNQALKSESDRAISNKDVEAEEKRRGLLK-------QIRDLENELENEKRGKSGAVSHRK 4851
+ L + S++ E EEK + L K I DLE L+ E++ + ++
Sbjct: 999 KEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKR 1058
Query: 4852 KIE-------NQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAA 5010
K++ +QI EL+ Q++ + + + A + ++ A
Sbjct: 1059 KLDGETTDLQDQIAELQAQVDELKVQLTKKEEELQGALARGDDETLHKNNALKVARELQA 1118
Query: 5011 LLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEA 5190
+ E F + +A R + + L + + A E + + E
Sbjct: 1119 QIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAA----QQELRTKREQ 1174
Query: 5191 KIAQXXXXXXXXQSNCELAI-DKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNR 5367
++A+ N E I D +++ LE+++ L + E KQ LE N+
Sbjct: 1175 EVAELKKALEDETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNK 1234
Query: 5368 DYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTT 5547
+ ++ L+ ++A+ ++ +L+ + QE A RL L +
Sbjct: 1235 ELACEVKVLQQ------------VKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAE-- 1280
Query: 5548 QQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANE 5727
+AN+ EL S L L+EAE + + ++ + D + +
Sbjct: 1281 -------KANKLQNELDNVSTL--------LEEAEKKGIKFAKDAAGLESQLQDTQELLQ 1325
Query: 5728 QLTRELMN 5751
+ TR+ +N
Sbjct: 1326 EETRQKLN 1333
>gi|41406064|ref|NP_005955.1| myosin, heavy polypeptide 10,
non-muscle; myosin heavy chain, nonmuscle type B;
cellular myosin heavy chain, type B type B [Homo sapiens]
Length = 1976
Score = 1819 bits (4712), Expect = 0.0
Identities = 940/1924 (48%), Positives = 1320/1924 (67%), Gaps = 13/1924 (0%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL V RA + +PAT A W +KL W+P + GF SIK E DEV+VEL + ++ +
Sbjct: 12 RYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMV 71
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDM+ELT LNEASVLHNLKDRYYS LIYTYSGLFCVVINPYK L
Sbjct: 72 NKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNL 131
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYSE++IE ++GKKRHEMPPHI+AI+++AYR MLQ+REDQSILCTGESGAGKTENTKKV
Sbjct: 132 PIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKV 191
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
IQYLAHVA + + + + N GELE QLLQANPILE+FGN+KTVKND
Sbjct: 192 IQYLAHVASSHKGRKDH--------------NIPGELERQLLQANPILESFGNAKTVKND 237
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFYQ+L G KS
Sbjct: 238 NSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKS 297
Query: 913 EYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 1092
+ LLEG +NYRFL N I +P D F T+ +M IMGF+ +EI S+++VVS+VL G
Sbjct: 298 DLLLEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFG 357
Query: 1093 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA 1272
N+ F +E+ +DQA + ++ V QK+CHLLG+ V+E +A L PRIKVGR++V KAQ +EQA
Sbjct: 358 NISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQA 417
Query: 1273 EFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICIN 1452
+FAVEA+AKA+YERLF+WLV RINK+LDRT RQGASFIGILDIAGFEIF++NSFEQ+CIN
Sbjct: 418 DFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCIN 477
Query: 1453 YTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDE 1623
YTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP IDLIE+P GVLALLDE
Sbjct: 478 YTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDE 537
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMD 1800
EC FPKA DK+FVEKL + H KF P ++ K+ F ++HYAG+VDY AD+WLMKNMD
Sbjct: 538 ECWFPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMD 597
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAFG--MRSRKGMFRTVSQLH 1968
PLN+NV L+ S+D FVA +WKD + G+ M ETAFG +++KGMFRTV QL+
Sbjct: 598 PLNDNVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLY 657
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
KE LTKLM TLRNT+P+FVRCIIPNHEK++GK++ +LVL+QLRCNGVLEGIRICRQGFPN
Sbjct: 658 KESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPN 717
Query: 2149 RVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAH 2328
R+ FQEFR RYEILTP+ IPK F+DGK++ +MI AL++D NLYRIGQSK+FFR GVLAH
Sbjct: 718 RIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAH 777
Query: 2329 LEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRL 2508
LEEERDLK+T +I+ FQA CRG+L+R+ + N AYLKLR+WQWWR+
Sbjct: 778 LEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRV 837
Query: 2509 FTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQ 2688
FTKVKPLLQVTR ++E++AKD+EL KE+ K+E + E E+K Q++ E+ ++ EQLQ
Sbjct: 838 FTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQ 897
Query: 2689 QESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXX 2868
E+E AE +++R RL + QELE I++D+ R+ ++K ++D
Sbjct: 898 AETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEE 957
Query: 2869 XXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLD 3048
+K + +D ++QL +
Sbjct: 958 QLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAE 1017
Query: 3049 HEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGK 3228
EE+AK+ K + + E + +LE+ L +E + + ELE+ KRKL E D +D +AE +
Sbjct: 1018 EEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQ 1077
Query: 3229 VEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKA 3408
++EL QL K++EELQ L R D+E+ + K +R++Q I EL+ED E+E+ +RNKA
Sbjct: 1078 IDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKA 1137
Query: 3409 EMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQ 3588
E +R++ +LE +K ++ D +D Q+L +++++EV K+A+E+ E +I++
Sbjct: 1138 EKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDM 1197
Query: 3589 KAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIH 3768
+ + + +EEL +Q+EQ K+ ++ LEK + + + ++A E+ +LQ +A+ + KRK
Sbjct: 1198 RQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKL 1257
Query: 3769 EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXX 3948
+A + E+ A ++E D + L ++ + ++ELD+++ + EE E + A+
Sbjct: 1258 DAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQL 1317
Query: 3949 XXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEAR 4128
TR K+ +R RQLE+EKN+L +++EE E R +LEK++ A + + +
Sbjct: 1318 QDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTK 1377
Query: 4129 RKAEESVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
+K ++ + + LEE +KK L+D E L ++LEE +A +++ ++K ++QQEL+D +++L+
Sbjct: 1378 KKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLD 1437
Query: 4303 NVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKE 4482
+ R + EK+QKKF+ +AEE+ + +RD E R++ET+ LSL ++ E
Sbjct: 1438 HQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALE 1497
Query: 4483 HLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQI 4662
EE +R + L+ +++D +S+KDD GKNVHELEK+KR+LE ++ +MR Q+EELED LQ
Sbjct: 1498 AKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQA 1557
Query: 4663 AEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVS 4842
EDA+LRLEV QA+K++ +R + +D + EEK+R L+KQ+R+LE ELE+E++ ++ AV+
Sbjct: 1558 TEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVA 1617
Query: 4843 HRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLRE 5022
+KK+E + +LE Q+E AN+ ++E +YQ E EEAR ++++I A +E
Sbjct: 1618 SKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKE 1677
Query: 5023 ADRKFRAVEAEREQLREANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAK 5193
+++K +++EAE QL+E +AR+ Q A G +EKRRLEA+
Sbjct: 1678 SEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEAR 1737
Query: 5194 IAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDY 5373
IAQ QSN EL D+ RK +Q++ + +L+ ER+ QK++ +Q LER N++
Sbjct: 1738 IAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKEL 1797
Query: 5374 KAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQ 5553
KAK+ ELE +S+ +A ++ALEAK+ LE+QL E +E+ AAN+ RR EK+L + Q
Sbjct: 1798 KAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQ 1857
Query: 5554 FEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQL 5733
EDE+R +Q KE +EK+N + + L+RQL+EAE+E +R R +QRE DD +ANE L
Sbjct: 1858 VEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGL 1917
Query: 5734 TREL 5745
+RE+
Sbjct: 1918 SREV 1921
Score = 83.2 bits (204), Expect = 7e-14
Identities = 113/608 (18%), Positives = 241/608 (39%), Gaps = 46/608 (7%)
Frame = +1
Query: 4066 GLRAHLEKE---------IHAARQGAGEARRKAEESVNQQLEELR--KKN---------- 4182
G+ AHLE+E I G RKA QQL L+ ++N
Sbjct: 773 GVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHW 832
Query: 4183 --------LRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKR 4338
++ + + +Q EE + E +L+ K+K Q ++E E+E K
Sbjct: 833 QWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEK-QTKVEGELEEMER---------KH 882
Query: 4339 QKKFESQ--MAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRR 4512
Q+ E + +AE+ A + + + M L ++ + +L++++ E EE +++ +
Sbjct: 883 QQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQ 942
Query: 4513 SLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEV 4692
+ ++++Q I D + + E E A++ L+ E +++++E+ + + ED + +
Sbjct: 943 NEKKKMQAHIQ---DLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKF-I 998
Query: 4693 TNQALKSESDRAISNKDVEAEEKRRGLLK-------QIRDLENELENEKRGKSGAVSHRK 4851
+ L + S++ E EEK + L K I DLE L+ E++ + ++
Sbjct: 999 KEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKR 1058
Query: 4852 KIE-------NQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAA 5010
K++ +QI EL+ Q++ + + + A + ++ A
Sbjct: 1059 KLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQA 1118
Query: 5011 LLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEA 5190
+ E F + +A R + + L + + A E + + E
Sbjct: 1119 QIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAA----QQELRTKREQ 1174
Query: 5191 KIAQXXXXXXXXQSNCELAI-DKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNR 5367
++A+ N E I D +++ LE+++ L + E KQ LE N+
Sbjct: 1175 EVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNK 1234
Query: 5368 DYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTT 5547
+ ++ L+ ++A+ ++ +L+ + QE A RL L +
Sbjct: 1235 ELACEVKVLQQ------------VKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKA 1282
Query: 5548 QQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANE 5727
+ ++E N+ L+EAE + + +++ + D + +
Sbjct: 1283 SKLQNELD-----------------NVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQ 1325
Query: 5728 QLTRELMN 5751
+ TR+ +N
Sbjct: 1326 EETRQKLN 1333
>gi|1346640|sp|P35580|MYHA_HUMAN Myosin heavy chain, nonmuscle type B
(Cellular myosin heavy chain, type B) (Nonmuscle myosin
heavy chain-B) (NMMHC-B)
gi|11276948|pir||A59252 myosin heavy chain, nonmuscle, form IIB -
human
gi|641958|gb|AAA99177.1| non-muscle myosin B
Length = 1976
Score = 1817 bits (4707), Expect = 0.0
Identities = 940/1924 (48%), Positives = 1319/1924 (67%), Gaps = 13/1924 (0%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL V RA + +PAT A W +KL W+P + GF SIK E DEV+VEL + ++ +
Sbjct: 12 RYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMV 71
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDM+ELT LNEASVLHNLKDRYYS LIYTYSGLFCVVINPYK L
Sbjct: 72 NKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNL 131
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYSE++IE ++GKKRHEMPPHI+AI+++AYR MLQ+REDQSILCTGESGAGKTENTKKV
Sbjct: 132 PIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKV 191
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
IQYLAHVA + + + + N GELE QLLQANPILE+FGN+KTVKND
Sbjct: 192 IQYLAHVASSHKGRKDH--------------NIPGELERQLLQANPILESFGNAKTVKND 237
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFYQ+L G KS
Sbjct: 238 NSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKS 297
Query: 913 EYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 1092
+ LLEG +NYRFL N I +P D F T+ +M IMGF+ +EI S+++VVS+VL G
Sbjct: 298 DLLLEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFG 357
Query: 1093 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA 1272
N+ F +E+ +DQA + ++ V QK+CHLLG+ V+E +A L PRIKVGR++V KAQ +EQA
Sbjct: 358 NISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQA 417
Query: 1273 EFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICIN 1452
+FAVEA+AKA+YERLF+WLV RINK+LDRT RQGASFIGILDIAGFEIF++NSFEQ+CIN
Sbjct: 418 DFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCIN 477
Query: 1453 YTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDE 1623
YTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP IDLIE+P GVLALLDE
Sbjct: 478 YTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDE 537
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMD 1800
EC FPKA DK+FVEKL + H KF P ++ K+ F ++HYAG+VDY AD+WLMKNMD
Sbjct: 538 ECWFPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMD 597
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAFG--MRSRKGMFRTVSQLH 1968
PLN+NV L+ S+D FVA +WKD + G+ M ETAFG +++KGMFRTV QL+
Sbjct: 598 PLNDNVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLY 657
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
KE LTKLM TLRNT+P+FVRCIIPNHEK++GK++ +LVL+QLRCNGVLEGIRICRQGFPN
Sbjct: 658 KESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPN 717
Query: 2149 RVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAH 2328
R+ FQEFR RYEILTP+ IPK F+DGK++ +MI AL++D NLYRIGQSK+FFR GVLAH
Sbjct: 718 RIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAH 777
Query: 2329 LEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRL 2508
LEEERDLK+T +I+ FQA CRG L+R+ + N AYLKLR+WQWWR+
Sbjct: 778 LEEERDLKITDIIIFFQAVCRGCLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRV 837
Query: 2509 FTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQ 2688
FTKVKPLLQVTR ++E++AKD+EL KE+ K+E + E E+K Q++ E+ ++ EQLQ
Sbjct: 838 FTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQ 897
Query: 2689 QESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXX 2868
E+E AE +++R RL + QELE I++D+ R+ ++K ++D
Sbjct: 898 AETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEE 957
Query: 2869 XXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLD 3048
+K + +D ++QL +
Sbjct: 958 QLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAE 1017
Query: 3049 HEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGK 3228
EE+AK+ K + + E + +LE+ L +E + + ELE+ KRKL E D +D +AE +
Sbjct: 1018 EEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQ 1077
Query: 3229 VEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKA 3408
++EL QL K++EELQ L R D+E+ + K +R++Q I EL+ED E+E+ +RNKA
Sbjct: 1078 IDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKA 1137
Query: 3409 EMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQ 3588
E +R++ +LE +K ++ D +D Q+L +++++EV K+A+E+ E +I++
Sbjct: 1138 EKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDM 1197
Query: 3589 KAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIH 3768
+ + + +EEL +Q+EQ K+ ++ LEK + + + ++A E+ +LQ +A+ + KRK
Sbjct: 1198 RQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKL 1257
Query: 3769 EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXX 3948
+A + E+ A ++E D + L ++ + ++ELD+++ + EE E + A+
Sbjct: 1258 DAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQL 1317
Query: 3949 XXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEAR 4128
TR K+ +R RQLE+EKN+L +++EE E R +LEK++ A + + +
Sbjct: 1318 QDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTK 1377
Query: 4129 RKAEESVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
+K ++ + + LEE +KK L+D E L ++LEE +A +++ ++K ++QQEL+D +++L+
Sbjct: 1378 KKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLD 1437
Query: 4303 NVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKE 4482
+ R + EK+QKKF+ +AEE+ + +RD E R++ET+ LSL ++ E
Sbjct: 1438 HQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALE 1497
Query: 4483 HLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQI 4662
EE +R + L+ +++D +S+KDD GKNVHELEK+KR+LE ++ +MR Q+EELED LQ
Sbjct: 1498 AKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQA 1557
Query: 4663 AEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVS 4842
EDA+LRLEV QA+K++ +R + +D + EEK+R L+KQ+R+LE ELE+E++ ++ AV+
Sbjct: 1558 TEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVA 1617
Query: 4843 HRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLRE 5022
+KK+E + +LE Q+E AN+ ++E +YQ E EEAR ++++I A +E
Sbjct: 1618 SKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKE 1677
Query: 5023 ADRKFRAVEAEREQLREANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAK 5193
+++K +++EAE QL+E +AR+ Q A G +EKRRLEA+
Sbjct: 1678 SEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEAR 1737
Query: 5194 IAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDY 5373
IAQ QSN EL D+ RK +Q++ + +L+ ER+ QK++ +Q LER N++
Sbjct: 1738 IAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKEL 1797
Query: 5374 KAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQ 5553
KAK+ ELE +S+ +A ++ALEAK+ LE+QL E +E+ AAN+ RR EK+L + Q
Sbjct: 1798 KAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQ 1857
Query: 5554 FEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQL 5733
EDE+R +Q KE +EK+N + + L+RQL+EAE+E +R R +QRE DD +ANE L
Sbjct: 1858 VEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGL 1917
Query: 5734 TREL 5745
+RE+
Sbjct: 1918 SREV 1921
Score = 82.8 bits (203), Expect = 9e-14
Identities = 97/532 (18%), Positives = 216/532 (40%), Gaps = 17/532 (3%)
Frame = +1
Query: 4207 KQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQ--MAEERVA 4380
+Q EE + E +L+ K+K Q ++E E+E K Q+ E + +AE+ A
Sbjct: 849 RQEEELQAKDEELLKVKEK-QTKVEGELEEMER---------KHQQLLEEKNILAEQLQA 898
Query: 4381 VQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDF 4560
+ + + M L ++ + +L++++ E EE +++ ++ ++++Q I D
Sbjct: 899 ETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQ---DL 955
Query: 4561 GKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNK 4740
+ + E E A++ L+ E +++++E+ + + ED + + + L + S++
Sbjct: 956 EEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKF-IKEKKLMEDRIAECSSQ 1014
Query: 4741 DVEAEEKRRGLLK-------QIRDLENELENEKRGKSGAVSHRKKIE-------NQIGEL 4878
E EEK + L K I DLE L+ E++ + ++K++ +QI EL
Sbjct: 1015 LAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAEL 1074
Query: 4879 EQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAER 5058
+ Q++ + + + A + ++ A + E F + +A R
Sbjct: 1075 QAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASR 1134
Query: 5059 EQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNC 5238
+ + L + + A E + + E ++A+ N
Sbjct: 1135 NKAEKQKRDLSEELEALKTELEDTLDTTAA----QQELRTKREQEVAELKKALEEETKNH 1190
Query: 5239 ELAI-DKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSR 5415
E I D +++ LE+++ L + E KQ LE N++ ++ L+
Sbjct: 1191 EAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQ----- 1245
Query: 5416 ARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKEL 5595
++A+ ++ +L+ + QE A RL L + + ++E
Sbjct: 1246 -------VKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELD-------- 1290
Query: 5596 LEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
N+ L+EAE + + +++ + D + ++ TR+ +N
Sbjct: 1291 ---------NVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLN 1333
>gi|45382679|ref|NP_990805.1| nonmuscle myosin heavy chain [Gallus
gallus]
gi|476389|pir||B43402 myosin heavy chain-B, neuronal - chicken
gi|212452|gb|AAA48988.1| nonmuscle myosin heavy chain
Length = 2007
Score = 1816 bits (4703), Expect = 0.0
Identities = 952/1949 (48%), Positives = 1323/1949 (67%), Gaps = 38/1949 (1%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL V RA + +PAT A W +KL W+P + GF SIK E DEVLVEL + ++ +
Sbjct: 12 RYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVLVELAENGKKALV 71
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDM+ELT LNEASVLHNLKDRYYS LIYTYSGLFCVVINPYK L
Sbjct: 72 NKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNL 131
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYSE++IE ++GKKRHEMPPHI+AI+++AYR MLQ+REDQSILCTGESGAGKTENTKKV
Sbjct: 132 PIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKV 191
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPI---GELEHQLLQANPILEAFGNSKTV 723
IQYLAHVA + + + NI P+ P+ GELE QLLQANPILE+FGN+KTV
Sbjct: 192 IQYLAHVASSHKGRK-----DHNI--PPESPKPVKHQGELERQLLQANPILESFGNAKTV 244
Query: 724 KNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAK 903
KNDNSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFYQ+L G
Sbjct: 245 KNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLAGAGEH 304
Query: 904 EKSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVL 1083
KS+ LLEG +NYRFL N I +P D F T+ +M IMGF+ DEI S+++VVS+VL
Sbjct: 305 LKSDLLLEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHDEILSMLKVVSSVL 364
Query: 1084 LLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQ 1263
GN+ F +E+ +DQA + ++ V QK+CHLLG+ V+E +A L PRIKVGR++V KAQ +
Sbjct: 365 QFGNISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTK 424
Query: 1264 EQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQI 1443
EQA+FAVEA+AKA+YERLF+WLV RINK+LDRT RQGASFIGILDIAGFEIF++NSFEQ+
Sbjct: 425 EQADFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQL 484
Query: 1444 CINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLAL 1614
CINYTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP IDLIE+P GVLAL
Sbjct: 485 CINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLAL 544
Query: 1615 LDEECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMK 1791
LDEEC FPKA DK+FVEKL + H KF P ++ K+ F ++HYAG+VDY AD+WLMK
Sbjct: 545 LDEECWFPKATDKTFVEKLVQEQGTHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMK 604
Query: 1792 NMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGICAA------------------------ 1899
NMDPLN+NV L+ S+D FVA +WKD E I A
Sbjct: 605 NMDPLNDNVATLLHQSSDKFVAELWKD-EIQNIQRACFYDNITGLHDPPVDRIVGLDQVT 663
Query: 1900 EMNETAFGM--RSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINS 2073
+ ETAFG +++KGMFRTV QL+KE LTKLM TLRNT+P+FVRCIIPNHEK++GK++
Sbjct: 664 GITETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDP 723
Query: 2074 NLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMIT 2253
+LVL+QLRCNGVLEGIRICRQGFPNR+ FQEFR RYEILTP+ IPK F+DGK++ +MI
Sbjct: 724 HLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIR 783
Query: 2254 ALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXX 2433
AL++D NLYRIGQSK+FFR GVLAHLEEERDLK+T +I+ FQA CRG+L+R+ +
Sbjct: 784 ALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQ 843
Query: 2434 XXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKME 2613
N AYLKLR+WQWWR+FTKVKPLLQVTR ++E++AKD+EL KE+ K+E
Sbjct: 844 LSALKILQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELMKVKEKQTKVE 903
Query: 2614 HDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLS 2793
+ E E+K Q++ E+ ++ EQLQ E+E AE +++R RL + QELE I++D+ R+
Sbjct: 904 AELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVE 963
Query: 2794 XXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQD 2973
++K ++D +K + +D
Sbjct: 964 EEEERNQILQNEKKKMQGHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLED 1023
Query: 2974 AYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSE 3153
T+QL + EE+AK+ K K + E + +LE+ L +E + + E
Sbjct: 1024 QNSKFLKEKKLMEDRIAECTSQLAEEEEKAKNLAKLKNKQEMMITDLEERLKKEEKTRQE 1083
Query: 3154 LEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQ 3333
LE+ KRKL E D +D +AE ++EEL QL K++EELQ L R DEE+ K
Sbjct: 1084 LEKAKRKLDGETTDLQDQIAELQAQIEELKIQLAKKEEELQAALARGDEEAVQKNNALKV 1143
Query: 3334 MRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRK 3513
+R++Q I EL+ED+E+E+ +RNKAE +R++ +LE +K ++ D +D Q+L +++
Sbjct: 1144 IRELQAQIAELQEDLESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKR 1203
Query: 3514 DEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQE 3693
++EV K+AIE+ E +I+E + + + +EEL +Q+EQ K+ ++ LEK + + +
Sbjct: 1204 EQEVAELKKAIEEETKNHEAQIQEIRQRHATALEELSEQLEQAKRFKANLEKNKQGLESD 1263
Query: 3694 RADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHL 3873
++A E+ +LQ +A+ + KRK +A + E+ A + E + + L ++ + ++ELD++
Sbjct: 1264 NKELACEVKVLQQVKAESEHKRKKLDAQVQELTAKVTEGERLRVELAEKANKLQNELDNV 1323
Query: 3874 NRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEK 4053
+ + EE E + A+ TR K+ +R RQLE+EKN L +++
Sbjct: 1324 SSLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNNLQEQQ 1383
Query: 4054 EEAEGLRAHLEKEIHAARQGAGEARRKAEESVN--QQLEELRKKNLRDVEHLQKQLEESE 4227
EE E R +LEK++ A + EA++K ++ + + LEE +KK L+D+E L ++LEE
Sbjct: 1384 EEEEEARKNLEKQMLALQAQLAEAKKKVDDDLGTIEGLEENKKKLLKDMESLSQRLEEKA 1443
Query: 4228 VAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRD 4407
+A +++ ++K ++QQEL+D ++L++ R + EK+QKKF+ +AEE+ + +RD
Sbjct: 1444 MAYDKLEKTKNRLQQELDDLMVDLDHQRQIVSNLEKKQKKFDQMLAEEKNISARYAEERD 1503
Query: 4408 AMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEK 4587
E R++ET+ LSL ++ E EE +R + L+ +++D +S+KDD GKNVHELEK
Sbjct: 1504 RAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEK 1563
Query: 4588 AKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRR 4767
+KR+LE ++ +MR Q+EELED LQ EDA+LRLEV QA+K++ +R + +D + EEK+R
Sbjct: 1564 SKRTLEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQARDEQNEEKKR 1623
Query: 4768 GLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXX 4947
L+KQ+R+LE ELE+E++ ++ AV+ +KK+E + +LE Q+E AN+ ++E
Sbjct: 1624 MLVKQVRELEAELEDERKQRALAVAAKKKMEMDLKDLEGQIEAANKARDEAIKQLRKLQA 1683
Query: 4948 XXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLRE---ANEGLMQARKQXXXX 5118
+YQ E EEAR ++++I A +E+++K + +EAE QL+E A+E + +Q
Sbjct: 1684 QMKDYQRELEEARASRDEIFAQSKESEKKLKGLEAEILQLQEEFAASERARRHAEQERDE 1743
Query: 5119 XXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTD 5298
A G +EKRRLEA+IAQ QSN EL ++ RK +Q++ + ++
Sbjct: 1744 LADEIANSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNERFRKTTLQVDTLNSE 1803
Query: 5299 LSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNV 5478
L+ ER+ QK+E +Q LER N++ KAK+ ELE +S+ +A ++ LEAK+ LE+QL
Sbjct: 1804 LAGERSAAQKSENARQQLERQNKELKAKLQELEGSVKSKFKATISTLEAKIAQLEEQLEQ 1863
Query: 5479 EGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDE 5658
E +E+ AAN+ RR EK+L + Q EDE+R +Q KE +EK+N + + L+RQL+EAE+E
Sbjct: 1864 EAKERAAANKLVRRTEKKLKEVFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEE 1923
Query: 5659 MSRERTKHRNVQREADDLLDANEQLTREL 5745
+R R +QRE DD +ANE L+RE+
Sbjct: 1924 ATRANASRRKLQRELDDATEANEGLSREV 1952
Score = 87.0 bits (214), Expect = 5e-15
Identities = 121/562 (21%), Positives = 234/562 (41%), Gaps = 27/562 (4%)
Frame = +1
Query: 4147 VNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRD 4326
V +Q EEL+ K+ E L K E+ + + + ++K QQ LE+ ++ E ++A
Sbjct: 878 VTRQEEELQAKD----EELMKVKEKQTKVEAELEEMERKHQQLLEEKNILAEQLQA---- 929
Query: 4327 SEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRV 4506
+ + E++ R+A +K L+ + L D E+RV EE +
Sbjct: 930 --ETELFAEAEEMRARLAAKKQELE-----EILHDLESRV--------------EEEEER 968
Query: 4507 RRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRL 4686
+ LQ E + + D + + E E A++ L+ E +++++E+ + + ED +
Sbjct: 969 NQILQNEKKKMQGHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKF 1028
Query: 4687 EVTNQALKSESDRAISNKDVEAEEKRRGLLK-------QIRDLENELENEKRGKSGAVSH 4845
+ + L + +++ E EEK + L K I DLE L+ E++ +
Sbjct: 1029 -LKEKKLMEDRIAECTSQLAEEEEKAKNLAKLKNKQEMMITDLEERLKKEEKTRQELEKA 1087
Query: 4846 RKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLR-- 5019
++K++ + +L+ Q+ EE ++ + A++ +E AAL R
Sbjct: 1088 KRKLDGETTDLQDQIAELQAQIEE----------------LKIQLAKKEEELQAALARGD 1131
Query: 5020 -EADRKFRAVEAERE---QLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLE 5187
EA +K A++ RE Q+ E E L + + + +E + L+
Sbjct: 1132 EEAVQKNNALKVIRELQAQIAELQEDLESEKASRNKAEKQKRDLSEELEALKTELEDTLD 1191
Query: 5188 AKIAQXXXXXXXXQSNCEL--AIDKQRK---AQVQ---------LEQITTDLSMERTLNQ 5325
AQ Q EL AI+++ K AQ+Q LE+++ L +
Sbjct: 1192 TTAAQQELRTKREQEVAELKKAIEEETKNHEAQIQEIRQRHATALEELSEQLEQAKRFKA 1251
Query: 5326 KTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAAN 5505
E KQ LE N++ ++ L+ ++A+ ++ +L+ + QE TA
Sbjct: 1252 NLEKNKQGLESDNKELACEVKVLQQ------------VKAESEHKRKKLDAQVQELTAKV 1299
Query: 5506 RAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHR 5685
RL L + +AN+ EL S+L L+EAE + +
Sbjct: 1300 TEGERLRVELAE---------KANKLQNELDNVSSL--------LEEAEKKGIKFAKDAA 1342
Query: 5686 NVQREADDLLDANEQLTRELMN 5751
+++ + D + ++ TR+ +N
Sbjct: 1343 SLESQLQDTQELLQEETRQKLN 1364
>gi|27807325|ref|NP_777259.1| myosin, heavy polypeptide 10, non-muscle
[Bos taurus]
gi|13431706|sp|Q27991|MYHA_BOVIN Myosin heavy chain, nonmuscle type B
(Cellular myosin heavy chain, type B) (Nonmuscle myosin
heavy chain-B) (NMMHC-B)
gi|4115748|dbj|BAA36494.1| nonmuscle myosin heavy chain B [Bos
taurus]
Length = 1976
Score = 1816 bits (4703), Expect = 0.0
Identities = 940/1924 (48%), Positives = 1321/1924 (67%), Gaps = 13/1924 (0%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL V RA + +PAT A W +KL W+P + GF SIK E DEVLVEL + ++ +
Sbjct: 12 RYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVLVELAENGKKAMV 71
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDM+ELT LNEASVLHNLKDRYYS LIYTYSGLFCVVINPYK L
Sbjct: 72 NKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNL 131
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYSE++IE ++GKKRHEMPPHI+AI+++AYR MLQ+REDQSILCTGESGAGKTENTKKV
Sbjct: 132 PIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKV 191
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
IQYLAHVA + + + + N GELE QLLQANPILE+FGN+KTVKND
Sbjct: 192 IQYLAHVASSHKGRKDH--------------NIPGELERQLLQANPILESFGNAKTVKND 237
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFYQ+L G KS
Sbjct: 238 NSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKS 297
Query: 913 EYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 1092
+ LLEG +NYRFL N I +P D F T+ +M IMGF+ +EI S+++VVS+VL G
Sbjct: 298 DLLLEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFG 357
Query: 1093 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA 1272
N+ F +E+ +DQA + ++ V QK+CHLLG+ V+E +A L PRIKVGR++V KAQ +EQA
Sbjct: 358 NISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQA 417
Query: 1273 EFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICIN 1452
+FAVEA+AKA+YERLF+WLV RINK+LDRT RQGASFIGILDIAGFEIF++NSFEQ+CIN
Sbjct: 418 DFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCIN 477
Query: 1453 YTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDE 1623
YTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP IDLIE+P GVLALLDE
Sbjct: 478 YTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDE 537
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMD 1800
EC FPKA DK+FVEKL + H KF P ++ K+ F ++HYAG+VDY AD+WLMKNMD
Sbjct: 538 ECWFPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMD 597
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAFG--MRSRKGMFRTVSQLH 1968
PLN+NV L+ S+D FVA +WKD + G+ M ETAFG +++KGMFRTV QL+
Sbjct: 598 PLNDNVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLY 657
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
KE LTKLM TLRNT+P+FVRCIIPNHEK++GK++ +LVL+QLRCNGVLEGIRICRQGFPN
Sbjct: 658 KESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPN 717
Query: 2149 RVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAH 2328
R+ FQEFR RYEILTP+ IPK F+DGK++ +MI AL++D NLYRIGQSK+FFR GVLAH
Sbjct: 718 RIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAH 777
Query: 2329 LEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRL 2508
LEEERDLK+T +I+ FQA CRG+L+R+ + N AYLKLR+WQWWR+
Sbjct: 778 LEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRV 837
Query: 2509 FTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQ 2688
FTKVKPLLQVTR ++E++AKD+EL KE+ K+E + E E+K Q++ E+ ++ EQLQ
Sbjct: 838 FTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQ 897
Query: 2689 QESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXX 2868
E+E AE +++R RL + QELE I++D+ R+ ++K ++D
Sbjct: 898 AETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEE 957
Query: 2869 XXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLD 3048
+K + +D ++QL +
Sbjct: 958 QLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAE 1017
Query: 3049 HEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGK 3228
EE+AK+ K + + E + +LE+ L +E + + ELE+ KRKL E D +D +AE +
Sbjct: 1018 EEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQ 1077
Query: 3229 VEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKA 3408
++EL Q+ K++EELQ L R D+E+ + K +R++Q I EL+ED E+E+ +RNKA
Sbjct: 1078 IDELKIQVAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKA 1137
Query: 3409 EMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQ 3588
E +R++ +LE +K ++ D +D Q+L +++++EV K+A+E+ + E +I++
Sbjct: 1138 EKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKSHEAQIQDM 1197
Query: 3589 KAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIH 3768
+ + + +EEL +Q+EQ K+ ++ LEK + + + ++A E+ +LQ +A+ + KRK
Sbjct: 1198 RQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKL 1257
Query: 3769 EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXX 3948
+A + E+ A ++E D + L ++ + ++ELD+++ + EE E + A
Sbjct: 1258 DAQVQELHAKVSEGDRLRVELAEKANKLQNELDNVSTLLEEAEKKGIKFAKDAAGLESQL 1317
Query: 3949 XXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEAR 4128
TR K+ +R RQLE+E+++L +++EE E R LEK++ A + + +
Sbjct: 1318 QDTQELLQEETRQKLNLSSRIRQLEEERSSLQEQQEEEEEARRSLEKQLQALQAQLTDTK 1377
Query: 4129 RKAEESVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
+K ++ + + LEE +KK L+DVE L ++LEE +A +++ ++K ++QQEL+D ++L+
Sbjct: 1378 KKVDDDLGTIENLEEAKKKLLKDVEVLSQRLEEKALAYDKLEKTKTRLQQELDDLLVDLD 1437
Query: 4303 NVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKE 4482
+ R + EK+QKKF+ +AEE+ + +RD E R++ET+ LSL ++ E
Sbjct: 1438 HQRQIVSNLEKKQKKFDQLLAEEKNISARYAEERDRAEAEAREKETKALSLARALEEALE 1497
Query: 4483 HLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQI 4662
EE++R + L+ +++D +S+KDD GKNVHELEK+KR+LE ++ +MR Q+EELED LQ
Sbjct: 1498 AREEAERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQA 1557
Query: 4663 AEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVS 4842
EDA+LRLEV QA+K++ +R + +D + EEK+R L+KQ+R+LE ELE+E++ ++ AV+
Sbjct: 1558 TEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVA 1617
Query: 4843 HRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLRE 5022
+KK+E + +LE Q+E AN+ ++E +YQ E EEAR ++++I A +E
Sbjct: 1618 SKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKE 1677
Query: 5023 ADRKFRAVEAEREQLREANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAK 5193
+++K +++EAE QL+E +AR+ Q A G +EKRRLEA+
Sbjct: 1678 SEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEIANSASGKSALLDEKRRLEAR 1737
Query: 5194 IAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDY 5373
IAQ QSN EL D+ RK +Q++ + T+L+ ER+ QK++ +Q LER N++
Sbjct: 1738 IAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNTELAAERSAAQKSDNARQQLERQNKEL 1797
Query: 5374 KAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQ 5553
KAK+ ELE +S+ +A ++ALEAK+ LE+QL E +E+ AAN+ RR EK+L + Q
Sbjct: 1798 KAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQ 1857
Query: 5554 FEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQL 5733
EDE+R +Q KE +EK+N + + L+RQL+EAE+E +R R +QRE DD +ANE L
Sbjct: 1858 VEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGL 1917
Query: 5734 TREL 5745
+RE+
Sbjct: 1918 SREV 1921
Score = 81.6 bits (200), Expect = 2e-13
Identities = 116/608 (19%), Positives = 242/608 (39%), Gaps = 46/608 (7%)
Frame = +1
Query: 4066 GLRAHLEKE---------IHAARQGAGEARRKAEESVNQQLEELR--KKN---------- 4182
G+ AHLE+E I G RKA QQL L+ ++N
Sbjct: 773 GVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHW 832
Query: 4183 --------LRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKR 4338
++ + + +Q EE + E +L+ K+K Q ++E E+E K
Sbjct: 833 QWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEK-QTKVEGELEEMER---------KH 882
Query: 4339 QKKFESQ--MAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRR 4512
Q+ E + +AE+ A + + + M L ++ + +L++++ E EE +++ +
Sbjct: 883 QQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQ 942
Query: 4513 SLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEV 4692
+ ++++Q I D + + E E A++ L+ E +++++E+ + + ED + +
Sbjct: 943 NEKKKMQAHIQ---DLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKF-I 998
Query: 4693 TNQALKSESDRAISNKDVEAEEKRRGLLK-------QIRDLENELENEKRGKSGAVSHRK 4851
+ L + S++ E EEK + L K I DLE L+ E++ + ++
Sbjct: 999 KEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKR 1058
Query: 4852 KIE-------NQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAA 5010
K++ +QI EL+ Q++ + + + A + ++ A
Sbjct: 1059 KLDGETTDLQDQIAELQAQIDELKIQVAKKEEELQGALARGDDETLHKNNALKVVRELQA 1118
Query: 5011 LLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEA 5190
+ E F + +A R + + L + + A E + + E
Sbjct: 1119 QIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAA----QQELRTKREQ 1174
Query: 5191 KIAQXXXXXXXXQSNCELAI-DKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNR 5367
++A+ + E I D +++ LE+++ L + E KQ LE N+
Sbjct: 1175 EVAELKKALEEETKSHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNK 1234
Query: 5368 DYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTT 5547
+ ++ L+ ++A+ ++ +L+ + QE A RL L +
Sbjct: 1235 ELACEVKVLQQ------------VKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAE-- 1280
Query: 5548 QQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANE 5727
+AN+ EL S L L+EAE + + ++ + D + +
Sbjct: 1281 -------KANKLQNELDNVSTL--------LEEAEKKGIKFAKDAAGLESQLQDTQELLQ 1325
Query: 5728 QLTRELMN 5751
+ TR+ +N
Sbjct: 1326 EETRQKLN 1333
>gi|212451|gb|AAA48987.1| nonmuscle myosin heavy chain
Length = 1997
Score = 1812 bits (4694), Expect = 0.0
Identities = 949/1946 (48%), Positives = 1319/1946 (67%), Gaps = 35/1946 (1%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL V RA + +PAT A W +KL W+P + GF SIK E DEVLVEL + ++ +
Sbjct: 12 RYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVLVELAENGKKALV 71
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDM+ELT LNEASVLHNLKDRYYS LIYTYSGLFCVVINPYK L
Sbjct: 72 NKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNL 131
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYSE++IE ++GKKRHEMPPHI+AI+++AYR MLQ+REDQSILCTGESGAGKTENTKKV
Sbjct: 132 PIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKV 191
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
IQYLAHVA + + + + N GELE QLLQANPILE+FGN+KTVKND
Sbjct: 192 IQYLAHVASSHKGRKDH--------------NIPGELERQLLQANPILESFGNAKTVKND 237
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFYQ+L G KS
Sbjct: 238 NSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLAGAGEHLKS 297
Query: 913 EYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 1092
+ LLEG +NYRFL N I +P D F T+ +M IMGF+ DEI S+++VVS+VL G
Sbjct: 298 DLLLEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHDEILSMLKVVSSVLQFG 357
Query: 1093 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA 1272
N+ F +E+ +DQA + ++ V QK+CHLLG+ V+E +A L PRIKVGR++V KAQ +EQA
Sbjct: 358 NISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQA 417
Query: 1273 EFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICIN 1452
+FAVEA+AKA+YERLF+WLV RINK+LDRT RQGASFIGILDIAGFEIF++NSFEQ+CIN
Sbjct: 418 DFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCIN 477
Query: 1453 YTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDE 1623
YTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP IDLIE+P GVLALLDE
Sbjct: 478 YTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDE 537
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMD 1800
EC FPKA DK+FVEKL + H KF P ++ K+ F ++HYAG+VDY AD+WLMKNMD
Sbjct: 538 ECWFPKATDKTFVEKLVQEQGTHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMD 597
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAEFAGICAA------------------------EMN 1908
PLN+NV L+ S+D FVA +WKD E I A +
Sbjct: 598 PLNDNVATLLHQSSDKFVAELWKD-EIQNIQRACFYDNITGLHDPPVDRIVGLDQVTGIT 656
Query: 1909 ETAFGM--RSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLV 2082
ETAFG +++KGMFRTV QL+KE LTKLM TLRNT+P+FVRCIIPNHEK++GK++ +LV
Sbjct: 657 ETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLV 716
Query: 2083 LEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALD 2262
L+QLRCNGVLEGIRICRQGFPNR+ FQEFR RYEILTP+ IPK F+DGK++ +MI AL+
Sbjct: 717 LDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIRALE 776
Query: 2263 IDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXX 2442
+D NLYRIGQSK+FFR GVLAHLEEERDLK+T +I+ FQA CRG+L+R+ +
Sbjct: 777 LDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSA 836
Query: 2443 XXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDF 2622
N AYLKLR+WQWWR+FTKVKPLLQVTR ++E++AKD+EL KE+ K+E +
Sbjct: 837 LKILQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELMKVKEKQTKVEAEL 896
Query: 2623 RENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXX 2802
E E+K Q++ E+ ++ EQLQ E+E AE +++R RL + QELE I++D+ R+
Sbjct: 897 EEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEE 956
Query: 2803 XXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYD 2982
++K ++D +K + +D
Sbjct: 957 ERNQILQNEKKKMQGHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNS 1016
Query: 2983 XXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQ 3162
T+QL + EE+AK+ K K + E + +LE+ L +E + + ELE+
Sbjct: 1017 KFLKEKKLMEDRIAECTSQLAEEEEKAKNLAKLKNKQEMMITDLEERLKKEEKTRQELEK 1076
Query: 3163 HKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRD 3342
KRKL E D +D +AE ++EEL QL K++EELQ L R DEE+ K +R+
Sbjct: 1077 AKRKLDGETTDLQDQIAELQAQIEELKIQLAKKEEELQAALARGDEEAVQKNNALKVIRE 1136
Query: 3343 MQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEE 3522
+Q I EL+ED+E+E+ +RNKAE +R++ +LE +K ++ D +D Q+L +++++E
Sbjct: 1137 LQAQIAELQEDLESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQE 1196
Query: 3523 VNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERAD 3702
V K+AIE+ E +I+E + + + +EEL +Q+EQ K+ ++ LEK + + + +
Sbjct: 1197 VAELKKAIEEETKNHEAQIQEIRQRHATALEELSEQLEQAKRFKANLEKNKQGLESDNKE 1256
Query: 3703 MAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRV 3882
+A E+ +LQ +A+ + KRK +A + E+ A + E + + L ++ + ++ELD+++ +
Sbjct: 1257 LACEVKVLQQVKAESEHKRKKLDAQVQELTAKVTEGERLRVELAEKANKLQNELDNVSSL 1316
Query: 3883 REEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEA 4062
EE E + A+ TR K+ +R RQLE+EKN L +++EE
Sbjct: 1317 LEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNNLQEQQEEE 1376
Query: 4063 EGLRAHLEKEIHAARQGAGEARRKAEESVN--QQLEELRKKNLRDVEHLQKQLEESEVAK 4236
E R +LEK++ A + EA++K ++ + + LEE +KK L+D+E L ++LEE +A
Sbjct: 1377 EEARKNLEKQMLALQAQLAEAKKKVDDDLGTIEGLEENKKKLLKDMESLSQRLEEKAMAY 1436
Query: 4237 ERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMS 4416
+++ ++K ++QQEL+D ++L++ R + EK+QKKF+ +AEE+ + +RD
Sbjct: 1437 DKLEKTKNRLQQELDDLMVDLDHQRQIVSNLEKKQKKFDQMLAEEKNISARYAEERDRAE 1496
Query: 4417 QELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKR 4596
E R++ET+ LSL ++ E EE +R + L+ +++D +S+KDD GKNVHELEK+KR
Sbjct: 1497 AEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKR 1556
Query: 4597 SLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLL 4776
+LE ++ +MR Q+EELED LQ EDA+LRLEV QA+K++ +R + +D + EEK+R L+
Sbjct: 1557 TLEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQARDEQNEEKKRMLV 1616
Query: 4777 KQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXX 4956
KQ+R+LE ELE+E++ ++ AV+ +KK+E + +LE Q+E AN+ ++E
Sbjct: 1617 KQVRELEAELEDERKQRALAVAAKKKMEMDLKDLEGQIEAANKARDEAIKQLRKLQAQMK 1676
Query: 4957 EYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLRE---ANEGLMQARKQXXXXXXX 5127
+YQ E EEAR ++++I A +E+++K + +EAE QL+E A+E + +Q
Sbjct: 1677 DYQRELEEARASRDEIFAQSKESEKKLKGLEAEILQLQEEFAASERARRHAEQERDELAD 1736
Query: 5128 XXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSM 5307
A G +EKRRLEA+IAQ QSN EL ++ RK +Q++ + ++L+
Sbjct: 1737 EIANSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNERFRKTTLQVDTLNSELAG 1796
Query: 5308 ERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQ 5487
ER+ QK+E +Q LER N++ KAK+ ELE +S+ +A ++ LEAK+ LE+QL E +
Sbjct: 1797 ERSAAQKSENARQQLERQNKELKAKLQELEGSVKSKFKATISTLEAKIAQLEEQLEQEAK 1856
Query: 5488 EKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSR 5667
E+ AAN+ RR EK+L + Q EDE+R +Q KE +EK+N + + L+RQL+EAE+E +R
Sbjct: 1857 ERAAANKLVRRTEKKLKEVFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATR 1916
Query: 5668 ERTKHRNVQREADDLLDANEQLTREL 5745
R +QRE DD +ANE L+RE+
Sbjct: 1917 ANASRRKLQRELDDATEANEGLSREV 1942
Score = 87.0 bits (214), Expect = 5e-15
Identities = 121/562 (21%), Positives = 234/562 (41%), Gaps = 27/562 (4%)
Frame = +1
Query: 4147 VNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRD 4326
V +Q EEL+ K+ E L K E+ + + + ++K QQ LE+ ++ E ++A
Sbjct: 868 VTRQEEELQAKD----EELMKVKEKQTKVEAELEEMERKHQQLLEEKNILAEQLQA---- 919
Query: 4327 SEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRV 4506
+ + E++ R+A +K L+ + L D E+RV EE +
Sbjct: 920 --ETELFAEAEEMRARLAAKKQELE-----EILHDLESRV--------------EEEEER 958
Query: 4507 RRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRL 4686
+ LQ E + + D + + E E A++ L+ E +++++E+ + + ED +
Sbjct: 959 NQILQNEKKKMQGHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKF 1018
Query: 4687 EVTNQALKSESDRAISNKDVEAEEKRRGLLK-------QIRDLENELENEKRGKSGAVSH 4845
+ + L + +++ E EEK + L K I DLE L+ E++ +
Sbjct: 1019 -LKEKKLMEDRIAECTSQLAEEEEKAKNLAKLKNKQEMMITDLEERLKKEEKTRQELEKA 1077
Query: 4846 RKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLR-- 5019
++K++ + +L+ Q+ EE ++ + A++ +E AAL R
Sbjct: 1078 KRKLDGETTDLQDQIAELQAQIEE----------------LKIQLAKKEEELQAALARGD 1121
Query: 5020 -EADRKFRAVEAERE---QLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLE 5187
EA +K A++ RE Q+ E E L + + + +E + L+
Sbjct: 1122 EEAVQKNNALKVIRELQAQIAELQEDLESEKASRNKAEKQKRDLSEELEALKTELEDTLD 1181
Query: 5188 AKIAQXXXXXXXXQSNCEL--AIDKQRK---AQVQ---------LEQITTDLSMERTLNQ 5325
AQ Q EL AI+++ K AQ+Q LE+++ L +
Sbjct: 1182 TTAAQQELRTKREQEVAELKKAIEEETKNHEAQIQEIRQRHATALEELSEQLEQAKRFKA 1241
Query: 5326 KTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAAN 5505
E KQ LE N++ ++ L+ ++A+ ++ +L+ + QE TA
Sbjct: 1242 NLEKNKQGLESDNKELACEVKVLQQ------------VKAESEHKRKKLDAQVQELTAKV 1289
Query: 5506 RAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHR 5685
RL L + +AN+ EL S+L L+EAE + +
Sbjct: 1290 TEGERLRVELAE---------KANKLQNELDNVSSL--------LEEAEKKGIKFAKDAA 1332
Query: 5686 NVQREADDLLDANEQLTRELMN 5751
+++ + D + ++ TR+ +N
Sbjct: 1333 SLESQLQDTQELLQEETRQKLN 1354
>gi|13928704|ref|NP_113708.1| myosin heavy chain 10, non-muscle;
nonmuscle myosin heavy chain-B; cellular myosin heavy
chain, type B; myosin heavy chain, nonmuscle type B;
nonmuscle myosin heavy chain IIB; MCH-B(B2); cellular
myosin heavy chain type B; myosin heavy chain nonmuscle
type B [Rattus norvegicus]
gi|13431672|sp|Q9JLT0|MYHA_RAT Myosin heavy chain, nonmuscle type B
(Cellular myosin heavy chain, type B) (Nonmuscle myosin
heavy chain-B) (NMMHC-B)
gi|7381235|gb|AAF61445.1| nonmuscle myosin heavy chain-B [Rattus
norvegicus]
Length = 1976
Score = 1812 bits (4693), Expect = 0.0
Identities = 940/1924 (48%), Positives = 1316/1924 (67%), Gaps = 13/1924 (0%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL V RA + +PAT A W +KL W+P + GF SIK E DEV+VEL + ++ +
Sbjct: 12 RYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMV 71
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDM+ELT LNEASVLHNLKDRYYS LIYTYSGLFCVVINPYK L
Sbjct: 72 NKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNL 131
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYSE++IE ++GKKRHE PPHI+AI+++AYR MLQ+R+DQSILCTGESGAGKTENTKKV
Sbjct: 132 PIYSENIIEMYRGKKRHEKPPHIYAISESAYRCMLQDRKDQSILCTGESGAGKTENTKKV 191
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
IQYLAHVA + + + + N GELE QLLQANPILE+FGN+KTVKND
Sbjct: 192 IQYLAHVASSHKGRKDH--------------NIPGELERQLLQANPILESFGNAKTVKND 237
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFYQ+L G KS
Sbjct: 238 NSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKS 297
Query: 913 EYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 1092
+ LLEG +NYRFL N I +P D F T+ +M IMGF+ +EI S+++VVS+VL G
Sbjct: 298 DLLLEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFG 357
Query: 1093 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA 1272
N+ F +E+ +DQA + ++ V QK+CHLLG+ V+E +A L PRIKVGR++V KAQ +EQA
Sbjct: 358 NISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQA 417
Query: 1273 EFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICIN 1452
+FAVEA+AKA+YERLF+WLV RINK+LDRT RQG SFIGILDIAGFEIF++NSFEQ+CIN
Sbjct: 418 DFAVEALAKATYERLFRWLVHRINKALDRTKRQGTSFIGILDIAGFEIFELNSFEQLCIN 477
Query: 1453 YTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDE 1623
YTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP IDLIE+P GVLALLDE
Sbjct: 478 YTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDE 537
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMD 1800
EC FPKA DK+FVEKL + H KF P ++ K+ F ++HYAG+VDY AD+WLMKNMD
Sbjct: 538 ECWFPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMD 597
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAFG--MRSRKGMFRTVSQLH 1968
PLN+NV L+ S+D FVA +WKD + G+ M ETAFG +++KGMFR V QL+
Sbjct: 598 PLNDNVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRNVGQLY 657
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
KE LTKLM TLRNT+P+FVRCIIPNHEK++GK++ +LVL+QLRCNGVLEGIRICRQGFPN
Sbjct: 658 KESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPN 717
Query: 2149 RVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAH 2328
R+ FQEFR RYEILTP+ IPK F+DGK++ +MI AL++D NLYRIGQSK+FFR GVLAH
Sbjct: 718 RIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAH 777
Query: 2329 LEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRL 2508
LEEERDLK+T +I+ FQA CRG+L+R+ + N AYLKLR+WQWWR+
Sbjct: 778 LEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRV 837
Query: 2509 FTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQ 2688
FTKVKPLLQVTR ++E++AKD+EL KE+ K+E + E E+K Q++ E+ ++ EQLQ
Sbjct: 838 FTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQ 897
Query: 2689 QESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXX 2868
E+E AE +++R RL + QELE I++D+ R+ ++K ++D
Sbjct: 898 AETELFAEAEEMRARLAAKKQELEEILHDLESRVEGEEERNQILQNEKKKMQAHIQDLEE 957
Query: 2869 XXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLD 3048
+K + +D ++QL +
Sbjct: 958 QLDEEEGARQKLQLEKVTAEAKIKKMEEEVLLLEDQNSKFIKEKKLMEDRIAECSSQLAE 1017
Query: 3049 HEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGK 3228
EE+AK+ K + + E + +LE+ L +E + + ELE+ KRKL E D +D +AE +
Sbjct: 1018 EEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQ 1077
Query: 3229 VEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKA 3408
V+EL QL K++EELQ L R D+E+ + K R++Q I EL+ED E+E+ +RNKA
Sbjct: 1078 VDELKVQLTKKEEELQGALARGDDETLHKNNALKVARELQAQIAELQEDFESEKASRNKA 1137
Query: 3409 EMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQ 3588
E +R++ +LE +K ++ D +D Q+L +++++EV K+A+E E +I++
Sbjct: 1138 EKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEDETKNHEAQIQDM 1197
Query: 3589 KAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIH 3768
+ + + +EEL +Q+EQ K+ ++ LEK + + + ++A E+ +LQ +A+ + KRK
Sbjct: 1198 RQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKL 1257
Query: 3769 EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXX 3948
+A + E+ A ++E D + L ++ + ++ELD+++ + EE E + A
Sbjct: 1258 DAQVQELHAKVSEGDRLRVELAEKANKLQNELDNVSTLLEEAEKKGMKFAKDAAGLESQL 1317
Query: 3949 XXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEAR 4128
TR K+ +R RQLE+EKN+L +++EE E R +LEK++ A + + +
Sbjct: 1318 QDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTK 1377
Query: 4129 RKAEESVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
+K ++ + + LEE +KK L+DVE L ++LEE +A +++ ++K ++QQEL+D +++L+
Sbjct: 1378 KKVDDDLGTIEGLEEAKKKLLKDVEALSQRLEEKVLAYDKLEKTKNRLQQELDDLTVDLD 1437
Query: 4303 NVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKE 4482
+ R + EK+QKKF+ +AEE+ + +RD E R++ET+ LSL ++ E
Sbjct: 1438 HQRQIVSNLEKKQKKFDQLLAEEKGISARYAEERDRAEAEAREKETKALSLARALEEALE 1497
Query: 4483 HLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQI 4662
EE +R + L+ +++D +S+KDD GKNVHELEK+KR+LE ++ +MR Q+EELED LQ
Sbjct: 1498 AKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQA 1557
Query: 4663 AEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVS 4842
EDA+LRLEV QA+K++ +R + +D + EEK+R LLKQ+R+LE ELE+E++ ++ AV+
Sbjct: 1558 TEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLLKQVRELEAELEDERKQRALAVA 1617
Query: 4843 HRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLRE 5022
+KK+E + +LE Q+E AN+ ++E +YQ E EEAR ++++I A +E
Sbjct: 1618 SKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKE 1677
Query: 5023 ADRKFRAVEAEREQLREANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAK 5193
+++K +++EAE QL+E +AR+ Q A G +EKRRLEA+
Sbjct: 1678 SEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEIANSASGKSALLDEKRRLEAR 1737
Query: 5194 IAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDY 5373
IAQ QSN EL D+ RK +Q++ + T+L+ ER+ QK++ +Q LER N++
Sbjct: 1738 IAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNTELAAERSAAQKSDNARQQLERQNKEL 1797
Query: 5374 KAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQ 5553
KAK+ ELE +S+ +A ++ALEAK+ LE+QL E +E+ AAN+ RR EK+L + Q
Sbjct: 1798 KAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQ 1857
Query: 5554 FEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQL 5733
EDE+R +Q KE +EK+N + + L+RQL+EAE+E +R R +QRE DD +ANE L
Sbjct: 1858 VEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGL 1917
Query: 5734 TREL 5745
+RE+
Sbjct: 1918 SREV 1921
Score = 82.8 bits (203), Expect = 9e-14
Identities = 117/608 (19%), Positives = 242/608 (39%), Gaps = 46/608 (7%)
Frame = +1
Query: 4066 GLRAHLEKE---------IHAARQGAGEARRKAEESVNQQLEELR--KKN---------- 4182
G+ AHLE+E I G RKA QQL L+ ++N
Sbjct: 773 GVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHW 832
Query: 4183 --------LRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKR 4338
++ + + +Q EE + E +L+ K+K Q ++E E+E K
Sbjct: 833 QWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEK-QTKVEGELEEMER---------KH 882
Query: 4339 QKKFESQ--MAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRR 4512
Q+ E + +AE+ A + + + M L ++ + +L++++ E EE +++ +
Sbjct: 883 QQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEGEEERNQILQ 942
Query: 4513 SLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEV 4692
+ ++++Q I D + + E E A++ L+ E +++++E+ + + ED + +
Sbjct: 943 NEKKKMQAHIQ---DLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEVLLLEDQNSKF-I 998
Query: 4693 TNQALKSESDRAISNKDVEAEEKRRGLLK-------QIRDLENELENEKRGKSGAVSHRK 4851
+ L + S++ E EEK + L K I DLE L+ E++ + ++
Sbjct: 999 KEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKR 1058
Query: 4852 KIE-------NQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAA 5010
K++ +QI EL+ Q++ + + + A + ++ A
Sbjct: 1059 KLDGETTDLQDQIAELQAQVDELKVQLTKKEEELQGALARGDDETLHKNNALKVARELQA 1118
Query: 5011 LLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEA 5190
+ E F + +A R + + L + + A E + + E
Sbjct: 1119 QIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAA----QQELRTKREQ 1174
Query: 5191 KIAQXXXXXXXXQSNCELAI-DKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNR 5367
++A+ N E I D +++ LE+++ L + E KQ LE N+
Sbjct: 1175 EVAELKKALEDETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNK 1234
Query: 5368 DYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTT 5547
+ ++ L+ ++A+ ++ +L+ + QE A RL L +
Sbjct: 1235 ELACEVKVLQQ------------VKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAE-- 1280
Query: 5548 QQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANE 5727
+AN+ EL S L L+EAE + + ++ + D + +
Sbjct: 1281 -------KANKLQNELDNVSTL--------LEEAEKKGMKFAKDAAGLESQLQDTQELLQ 1325
Query: 5728 QLTRELMN 5751
+ TR+ +N
Sbjct: 1326 EETRQKLN 1333
>gi|422615|pir||A47297 myosin heavy chain form B, nonmuscle - African
clawed frog
gi|214624|gb|AAA49915.1| nonmuscle myosin heavy chain b
Length = 1992
Score = 1790 bits (4637), Expect = 0.0
Identities = 933/1926 (48%), Positives = 1310/1926 (67%), Gaps = 15/1926 (0%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL V R V +P T A W +KL WVP + GF SIK E DEV+VEL + ++ +
Sbjct: 12 RYLFVDRDVVYNPTTQADWTAKKLVWVPSERHGFEAASIKEERGDEVVVELAENGKKAIV 71
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDM+ELT LNEASVLHNLKDRYYS LIYTYSGLFCVVINPYK L
Sbjct: 72 NKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNL 131
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYSE++IE ++GKKRHEMPPHI+AI+++AYR MLQ+REDQSILCTGESGAGKTENTKKV
Sbjct: 132 PIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKV 191
Query: 553 IQYLAHVAGATRNKSLNAAAQQN--IVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
IQYLAHVA + + K + ++ ++ GELE QLLQANPILE+FGN+KTVK
Sbjct: 192 IQYLAHVASSHKGKKDHTIPTESPKAIKHQSGSLLYGELERQLLQANPILESFGNAKTVK 251
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
NDNSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFYQ+L G
Sbjct: 252 NDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLAGSGEHL 311
Query: 907 KSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLL 1086
KS+ LL+G +NYRF+ N I +P D F T+ +M IMGF+ +EI S+++VVS+VL
Sbjct: 312 KSDLLLDGFNNYRFVSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQ 371
Query: 1087 LGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQE 1266
GN+ F +E+ +DQA + ++ QK+CHLLGL ++E +A L PRIKVGR++V KAQ +E
Sbjct: 372 FGNIVFKKERNTDQASMPENTAAQKLCHLLGLNIMEFTRAILTPRIKVGRDYVQKAQTKE 431
Query: 1267 QAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQIC 1446
QA+FAVEA+ KA+YERLF+WLV RINK+LDRT RQGASFIGILDIAGFEIF++NSFEQ+C
Sbjct: 432 QADFAVEALRKATYERLFRWLVYRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLC 491
Query: 1447 INYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALL 1617
INYTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP IDLIE+P GVLALL
Sbjct: 492 INYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANSPGVLALL 551
Query: 1618 DEECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKN 1794
DEEC FPKA DK+FV+KL + H KF P ++ K+ F ++HYAGRVDY AD+WL+KN
Sbjct: 552 DEECWFPKATDKTFVDKLVQEQGTHSKFQKPRQLKDKADFCIIHYAGRVDYKADEWLLKN 611
Query: 1795 MDPLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAFG--MRSRKGMFRTVSQ 1962
MDPLN+NV L+ S+D FV+ +WKD + G+ A M ETAFG +++KGMFRTV Q
Sbjct: 612 MDPLNDNVATLLHQSSDKFVSELWKDVDRIVGLDQVAGMAETAFGAAYKTKKGMFRTVGQ 671
Query: 1963 LHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGF 2142
L+KE L KLM TLRNT+P+FVRCIIPNHEK++GK++ +LVL+QLRCNGVLEGIRICRQGF
Sbjct: 672 LYKESLAKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGF 731
Query: 2143 PNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVL 2322
PNR+ FQEFR RYEILTP+ IP+ F+DGK++ +MI +L++D NLYRIGQSK+FFR GVL
Sbjct: 732 PNRIVFQEFRQRYEILTPNSIPRGFMDGKQACERMIRSLELDPNLYRIGQSKIFFRAGVL 791
Query: 2323 AHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWW 2502
AHLEEERDLK+T +I+ FQA CRG+L+R+ + N AYLKLR+WQWW
Sbjct: 792 AHLEEERDLKITDIIVLFQAVCRGYLARKAFAKKQQQLIALKVLQRNCAAYLKLRHWQWW 851
Query: 2503 RLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQ 2682
RLFTKVKPLLQVTR ++E+ AKD+EL KE+ K+E + + E+K Q++ E+ ++ EQ
Sbjct: 852 RLFTKVKPLLQVTRQEEELVAKDEELLKVKEKQSKVEGELVDMEQKHQQLVEEKNILAEQ 911
Query: 2683 LQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDX 2862
L E+E AE +++R RL + QE+E I+ D+ R+ ++K V+D
Sbjct: 912 LHAETELFAEAEEMRARLAIKKQEMEEILRDLEIRMEEEEERNQVLQNEKKKMQTHVQD- 970
Query: 2863 XXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQL 3042
+K + +D T+QL
Sbjct: 971 LEEQLDEEEAAQKLQLEKVTAEAKIKKMEEDILVLEDQNSKFLKEKKLLEERIAESTSQL 1030
Query: 3043 LDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKM 3222
+ EE+AK+ K K + E + +LE+ L +E + + ELE+ KRKL E D +D +AE
Sbjct: 1031 AEEEEKAKNLAKLKNKQEMMISDLEERLKKEEKTRQELEKAKRKLDGETTDFQDQIAELQ 1090
Query: 3223 GKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARN 3402
++EEL QL K++EELQ L R DEE K +R++Q I EL+ED+E+E+ +RN
Sbjct: 1091 AQIEELKLQLAKKEEELQAALARGDEEVLQKNNTLKLVRELQAQIAELQEDLESEKASRN 1150
Query: 3403 KAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIE 3582
KAE +R++ +LE +K ++ D +D Q+L +++++EV +++IE+ E +I+
Sbjct: 1151 KAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELRKSIEEETRNHEAQIQ 1210
Query: 3583 EQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRK 3762
E + + + +EEL +Q+EQ K+ + LEK + + + ++A E+ LQ +A+ + KRK
Sbjct: 1211 EMRQRQATALEELSEQLEQAKRFKVNLEKNKQSLESDNKELATEVKSLQQMKAESEYKRK 1270
Query: 3763 IHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXX 3942
E + E+ A + E D + ++++ + ++EL++++ + EE E + + +A+
Sbjct: 1271 KLEGQVQELHAKVLEGDRLRADMVEKSSKLQNELENVSSLLEEAEKKGIKLAKDVASMES 1330
Query: 3943 XXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGE 4122
TR K+ +R RQLE+EKN L +++EE E R LEK+I + + E
Sbjct: 1331 QLQDTQELLQEETRQKLNQSSRIRQLEEEKNNLQEQQEEEEEARKSLEKQILSLQSQLIE 1390
Query: 4123 ARRKAEESVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSME 4296
A++K ++ V + LEE++KK L+D E L ++LEE +A E++ ++K ++QQEL+D ++
Sbjct: 1391 AKKKVDDEVGTIEGLEEVKKKLLKDTEGLGQRLEEKIIAYEKLEKTKNRLQQELDDLMVD 1450
Query: 4297 LENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIM 4476
L++ R + EK+QKKF+ +AEE+ + +RD + R++ET+ LSL +D
Sbjct: 1451 LDHQRQIVSNLEKKQKKFDQLLAEEKNISARHAEERDRAEADAREKETKALSLARALDEA 1510
Query: 4477 KEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNL 4656
E +E +R+ + L+ E++D +S+KDD GKNVHELEK+KR+L+ ++ +MR Q+EELED L
Sbjct: 1511 LEAQDEFERLNKQLRAEMEDLMSSKDDVGKNVHELEKSKRALDQQVEEMRTQLEELEDEL 1570
Query: 4657 QIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGA 4836
Q EDA+LRLEV QA+K++ +R + +D + EEK+R L+KQ+R+LE ELE+E++ ++ A
Sbjct: 1571 QGTEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRALVKQVRELEAELEDERKQRAMA 1630
Query: 4837 VSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALL 5016
V+ +KK+E + + E Q+E AN+ +E+ +YQ E EEAR +++DI A
Sbjct: 1631 VAIKKKLEMDMKDFESQIEAANKGREDAIKQLRKLQAQTKDYQRELEEARASRDDIFAQS 1690
Query: 5017 READRKFRAVEAEREQLRE---ANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLE 5187
+E ++K + +EAE QL+E A+E + +Q G +EKRRLE
Sbjct: 1691 KENEKKLKGLEAEILQLQEELAASERSRRHAEQERDELADEISNSTSGKSALLDEKRRLE 1750
Query: 5188 AKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNR 5367
A+IA QSN EL D+ RK +Q++ + ++L+ ER+ QK+E +Q LER N+
Sbjct: 1751 ARIAHLEEELEEEQSNMELLNDRFRKTTLQVDTLNSELAAERSSGQKSENARQQLERQNK 1810
Query: 5368 DYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTT 5547
+ KAK+ ELE +S+ +A +A LE+K+ LE+QL E +E+ A+N+ RR EK+L +
Sbjct: 1811 ELKAKLQELEGSVKSKFKATIATLESKIAQLEEQLEQEAKERVASNKLVRRTEKKLKEVF 1870
Query: 5548 QQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANE 5727
Q EDE+R +Q KE +EK+N + + L+RQL+EAE+E +R R +QRE DD +ANE
Sbjct: 1871 MQVEDERRHADQYKEQMEKANTRMKQLKRQLEEAEEEATRANASARKLQRELDDATEANE 1930
Query: 5728 QLTREL 5745
L+RE+
Sbjct: 1931 VLSREV 1936
Score = 84.7 bits (208), Expect = 2e-14
Identities = 102/533 (19%), Positives = 222/533 (41%), Gaps = 21/533 (3%)
Frame = +1
Query: 4216 EESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQ--MAEERVAVQK 4389
EE VAK+ L K+ Q ++E +++E +K Q+ E + +AE+ A +
Sbjct: 867 EEELVAKDEELLKVKEKQSKVEGELVDME---------QKHQQLVEEKNILAEQLHAETE 917
Query: 4390 ALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKN 4569
+ + M L ++ + +L +++I E EE ++V ++ ++++Q + D +
Sbjct: 918 LFAEAEEMRARLAIKKQEMEEILRDLEIRMEEEEERNQVLQNEKKKMQTHVQ---DLEEQ 974
Query: 4570 VHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVE 4749
+ E E+A + L+ E +++++E+++ + ED + + + L E +++ E
Sbjct: 975 LDE-EEAAQKLQLEKVTAEAKIKKMEEDILVLEDQNSKF-LKEKKLLEERIAESTSQLAE 1032
Query: 4750 AEEKRRGLLK-------QIRDLENELENEKRGKSGAVSHRKKIE-------NQIGELEQQ 4887
EEK + L K I DLE L+ E++ + ++K++ +QI EL+ Q
Sbjct: 1033 EEEKAKNLAKLKNKQEMMISDLEERLKKEEKTRQELEKAKRKLDGETTDFQDQIAELQAQ 1092
Query: 4888 LEVAN----RLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAE 5055
+E + +EE + + R+ + IA L + + + +
Sbjct: 1093 IEELKLQLAKKEEELQAALARGDEEVLQKNNTLKLVRELQAQIAELQEDLESEKASRNKA 1152
Query: 5056 REQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSN 5235
+Q R+ +E L + + + E + + E ++A+ N
Sbjct: 1153 EKQKRDLSEELEALKTELEDTLDTTAAQQ--------ELRTKREQEVAELRKSIEEETRN 1204
Query: 5236 CELAIDKQRKAQVQ-LEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQS 5412
E I + R+ Q LE+++ L + E KQSLE N++ ++ L+
Sbjct: 1205 HEAQIQEMRQRQATALEELSEQLEQAKRFKVNLEKNKQSLESDNKELATEVKSLQQ---- 1260
Query: 5413 RARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKE 5592
++A+ +Y +L + QE A RL + + + + ++E
Sbjct: 1261 --------MKAESEYKRKKLEGQVQELHAKVLEGDRLRADMVEKSSKLQNELE------- 1305
Query: 5593 LLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
N+ L+EAE + + +++ + D + ++ TR+ +N
Sbjct: 1306 ----------NVSSLLEEAEKKGIKLAKDVASMESQLQDTQELLQEETRQKLN 1348
>gi|45382693|ref|NP_990808.1| myosin heavy chain, nonmuscle [Gallus
gallus]
gi|127759|sp|P14105|MYH9_CHICK Myosin heavy chain, nonmuscle
(Cellular myosin heavy chain) (NMMHC)
gi|104780|pir||A33977 myosin heavy chain, nonmuscle - chicken
gi|212383|gb|AAA48974.1| myosin heavy chain
Length = 1959
Score = 1785 bits (4622), Expect = 0.0
Identities = 923/1924 (47%), Positives = 1296/1924 (66%), Gaps = 13/1924 (0%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL V + + +P T A WA +KL WVP + GF S+K E DE +VEL + ++V +
Sbjct: 8 KYLYVDKNIINNPLTQADWAAKKLVWVPSEKSGFEAASLKEEVGDEAIVELAENGKKVKV 67
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDM+ELT LNEASVLHNLK+RYYS LIYTYSGLFCVVINPYK L
Sbjct: 68 NKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNL 127
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYSE+++E +KGKKRHEMPPHI+AI DTAYRSM+Q+REDQSILCTGESGAGKTENTKKV
Sbjct: 128 PIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKV 187
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
IQYLAHVA + ++K GELE QLLQANPILEAFGN+KTVKND
Sbjct: 188 IQYLAHVASSHKSKKDQ-----------------GELERQLLQANPILEAFGNAKTVKND 230
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA++ER+FHIFY +L G K+
Sbjct: 231 NSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKT 290
Query: 913 EYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 1092
+ LLE + YRFL N +T+P D F T+ +MRIMG D+E +++V+S VL LG
Sbjct: 291 DLLLEPYNKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPDEEQIGLLKVISGVLQLG 350
Query: 1093 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA 1272
N+ F +E+ +DQA + D+ QKV HLLG+ V + + L PRIKVGR++V KAQ +EQA
Sbjct: 351 NIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQA 410
Query: 1273 EFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICIN 1452
+FA+EA+AKA+YE++F+WLV RINK+LD+T RQGASFIGILDIAGFEIF++NSFEQ+CIN
Sbjct: 411 DFAIEALAKATYEQMFRWLVMRINKALDKTKRQGASFIGILDIAGFEIFELNSFEQLCIN 470
Query: 1453 YTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDE 1623
YTNEKLQQLFN+TMFILEQEEYQ EGIEW+FIDFGLDLQP IDLIEKP G+LALLDE
Sbjct: 471 YTNEKLQQLFNHTMFILEQEEYQNEGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDE 530
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMD 1800
EC FPKA DKSFVEK+ + HPKF P ++ K+ F ++HYAG+VDY AD+WLMKNMD
Sbjct: 531 ECWFPKATDKSFVEKVVQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMD 590
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQLH 1968
PLN+N+ L+ S+D FV+ +WKD + G+ A M+ETA ++RKGMFRTV QL+
Sbjct: 591 PLNDNIATLLHQSSDKFVSELWKDVDRIVGLDQVAGMSETALPGAFKTRKGMFRTVGQLY 650
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
KEQL KLM TLRNT+P+FVRCIIPNHEKK+GK++ +LVL+QLRCNGVLEGIRICRQGFPN
Sbjct: 651 KEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPN 710
Query: 2149 RVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAH 2328
RV FQEFR RYEILTP+ IPK F+DGK++ MI AL++D+NLYRIGQSKVFFR GVLAH
Sbjct: 711 RVVFQEFRQRYEILTPNAIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAH 770
Query: 2329 LEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRL 2508
LEEERDLK+T +I+ FQA CRG+L+R+ + N AYLKLRNWQWWRL
Sbjct: 771 LEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRL 830
Query: 2509 FTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQ 2688
FTKVKPLLQV+R ++E+ AK++EL KE+ L E+ E E Q++ E+ +QEQLQ
Sbjct: 831 FTKVKPLLQVSRQEEEMMAKEEELIKVKEKQLAAENRLSEMETFQAQLMAEKMQLQEQLQ 890
Query: 2689 QESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXX 2868
E+E AE ++IR RL + QELE I +D+ R+ ++K + +++
Sbjct: 891 AEAELCAEAEEIRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEE 950
Query: 2869 XXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLD 3048
+K + +D TT L +
Sbjct: 951 QLEEEESARQKLQLEKVTTEAKLKKLEEDVIVLEDQNLKLAKEKKLLEDRMSEFTTNLTE 1010
Query: 3049 HEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGK 3228
EE++K K K + E + +LE+ L RE + + ELE+ +RKL + D D +AE +
Sbjct: 1011 EEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSSDLHDQIAELQAQ 1070
Query: 3229 VEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKA 3408
+ EL QL K++EELQ L R +EE+A + K++R++++ I EL+ED+E+ER +RNKA
Sbjct: 1071 IAELKIQLSKKEEELQAALARVEEEAAQKNMALKKIRELESQITELQEDLESERASRNKA 1130
Query: 3409 EMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQ 3588
E +R++ +LE +K ++ D +D Q+L S++++EV K+ +E T E +I+E
Sbjct: 1131 EKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVTVLKKTLEDEAKTHEAQIQEM 1190
Query: 3589 KAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIH 3768
+ K S+ +EEL +Q+EQ K+ ++ LEK + + ERA+++ E+ +L + D + KRK
Sbjct: 1191 RQKHSQAIEELAEQLEQTKRVKANLEKAKQALESERAELSNEVKVLLQGKGDAEHKRKKV 1250
Query: 3769 EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXX 3948
+A L E+Q E + K L +++ + + ELD++ + + + + + +
Sbjct: 1251 DAQLQELQVKFTEGERVKTELAERVNKLQVELDNVTGLLNQSDSKSIKLAKDFSALESQL 1310
Query: 3949 XXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEAR 4128
TRLK++ + +Q EDEKNAL ++ EE E + +LEK+I +Q A EAR
Sbjct: 1311 QDTQELLQEETRLKLSFSTKLKQTEDEKNALKEQLEEEEEAKRNLEKQISVLQQQAVEAR 1370
Query: 4129 RKAEESVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
+K ++ + + EE +KK +D+E L ++ EE A +++ ++K ++QQEL+D +++L+
Sbjct: 1371 KKMDDGLGCLEIAEEAKKKLQKDLESLTQRYEEKIAAYDKLEKTKTRLQQELDDIAVDLD 1430
Query: 4303 NVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKE 4482
+ R + + EK+QKKF+ +AEE+ K +RD E R++ET+ LSL ++ E
Sbjct: 1431 HQRQTVSNLEKKQKKFDQLLAEEKNISAKYAEERDRAEAEAREKETKALSLARALEEAIE 1490
Query: 4483 HLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQI 4662
E +RV + + E++D +S+KDD GK+VHELEKAKR+LE ++ +M+ Q+EELED LQ
Sbjct: 1491 QKAELERVNKQFRTEMEDLMSSKDDVGKSVHELEKAKRALEQQVEEMKTQLEELEDELQA 1550
Query: 4663 AEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVS 4842
EDA+LRLEV QA+K++ DR + +D + EEKR+ L++Q+R++E ELE+E++ +S AV+
Sbjct: 1551 TEDAKLRLEVNQQAMKAQFDRDLLGRDEQNEEKRKQLIRQVREMEVELEDERKQRSIAVA 1610
Query: 4843 HRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLRE 5022
RKK+E + +LE ++ AN+ ++E +Y E E+ R ++E+I A +E
Sbjct: 1611 ARKKLELDLKDLESHIDTANKNRDEAIKHVRKLQAQMKDYMRELEDTRTSREEILAQAKE 1670
Query: 5023 ADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKG---GGISSEEKRRLEAK 5193
++K +++EAE QL+E +A++Q A G ++ EEKRRLEA+
Sbjct: 1671 NEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALAMEEKRRLEAR 1730
Query: 5194 IAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDY 5373
IAQ Q N E+ D+ +KA +Q++Q+ DL+ ER+ QK E +Q +ER N++
Sbjct: 1731 IAQLEEELEEEQGNTEIINDRLKKANLQIDQMNADLNAERSNAQKNENARQQMERQNKEL 1790
Query: 5374 KAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQ 5553
K K+ E+ES +S+ +A + ALEAK+ LE+QL++E +E+ AA++ RR EK+L D Q
Sbjct: 1791 KLKLQEMESAVKSKYKATITALEAKIVQLEEQLDMETKERQAASKQVRRAEKKLKDILLQ 1850
Query: 5554 FEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQL 5733
+DE+R EQ K+ +K+N++ + L+RQL+EAE+E R + R +QRE DD + + +
Sbjct: 1851 VDDERRNAEQFKDQADKANMRLKQLKRQLEEAEEEAQRANVR-RKLQRELDDATETADAM 1909
Query: 5734 TREL 5745
RE+
Sbjct: 1910 NREV 1913
>gi|45384060|ref|NP_990605.1| MHC mRNA [Gallus gallus]
gi|86369|pir||S03166 myosin heavy chain, gizzard smooth muscle
[similarity] - chicken
gi|63634|emb|CAA29793.1| unnamed protein product [Gallus gallus]
Length = 1979
Score = 1779 bits (4609), Expect = 0.0
Identities = 927/1926 (48%), Positives = 1306/1926 (67%), Gaps = 13/1926 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
D ++L V + V +P A W+ +KL WVP + GF SIK E DEV VEL + ++V
Sbjct: 9 DEKFLFVDKNFVNNPLAQADWSAKKLVWVPSEKHGFEAASIKEEKGDEVTVELQENGKKV 68
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
T+S+DD+QK NPPKF K+EDM+ELT LNEASVLHNL++RY+S LIYTYSGLFCVVINPYK
Sbjct: 69 TLSKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVINPYK 128
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
+LPIYSE +I+ +KGKKRHEMPPHI+AIADTAYRSMLQ+REDQSILCTGESGAGKTENTK
Sbjct: 129 QLPIYSEKIIDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTK 188
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVIQYLA VA + + K A+ + ++ P GELE QLLQANPILEAFGN+KTVK
Sbjct: 189 KVIQYLAVVASSHKGKRTPASLKVHLF-------PYGELEKQLLQANPILEAFGNAKTVK 241
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
NDNSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFY ++ G S +
Sbjct: 242 NDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQAKDERTFHIFYYLIAGASEQM 301
Query: 907 KSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLL 1086
+++ LLEG +NY FL N + +P D + F T+ +M IMGF ++E +SI+RVVS+VL
Sbjct: 302 RNDLLLEGFNNYTFLSNGHVPIPAQQDDEMFQETLEAMTIMGFTEEEQTSILRVVSSVLQ 361
Query: 1087 LGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQE 1266
LGN+ F +E+ +DQA + D+ QKVCHL+G+ V + ++ L PRIKVGR+ V KAQ +E
Sbjct: 362 LGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKE 421
Query: 1267 QAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQIC 1446
QA+FA+EA+AKA +ERLF+W++TR+NK+LD+T RQGASF+GILDIAGFEIF+INSFEQ+C
Sbjct: 422 QADFAIEALAKAKFERLFRWILTRVNKALDKTKRQGASFLGILDIAGFEIFEINSFEQLC 481
Query: 1447 INYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALL 1617
INYTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP I+LIE+P GVLALL
Sbjct: 482 INYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPTNPPGVLALL 541
Query: 1618 DEECLFPKANDKSFVEKLQKTHNKHPKF-IVPDMRSKSHFAVVHYAGRVDYSADQWLMKN 1794
DEEC FPKA D SFVEKL + H KF ++ K+ F ++HYAG+V Y+A WL KN
Sbjct: 542 DEECWFPKATDTSFVEKLIQEQGNHAKFQKSKQLKDKTEFCILHYAGKVTYNASAWLTKN 601
Query: 1795 MDPLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQ 1962
MDPLN+NV L+ S+D FVA +WKD + G+ A+M E++ +++KGMFRTV Q
Sbjct: 602 MDPLNDNVTSLLNQSSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQ 661
Query: 1963 LHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGF 2142
L+KEQLTKLMTTLRNT+P+FVRCIIPNHEK++GK++++LVLEQLRCNGVLEGIRICRQGF
Sbjct: 662 LYKEQLTKLMTTLRNTNPNFVRCIIPNHEKRAGKLDAHLVLEQLRCNGVLEGIRICRQGF 721
Query: 2143 PNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVL 2322
PNR+ FQEFR RYEIL + IPK F+DGK++ MI AL++D NLYRIGQSK+FFRTGVL
Sbjct: 722 PNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVL 781
Query: 2323 AHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWW 2502
AHLEEERDLK+T +I+ FQAQCRG+L+R+ + N AYLKLRNWQWW
Sbjct: 782 AHLEEERDLKITDVIIAFQAQCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWW 841
Query: 2503 RLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQ 2682
RLFTKVKPLLQVTR ++E++AKD+EL+ TKER K E + +E E+K Q+ E+ ++QE+
Sbjct: 842 RLFTKVKPLLQVTRQEEEMQAKDEELQRTKERQQKAEAELKELEQKHTQLCEEKNLLQEK 901
Query: 2683 LQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDX 2862
LQ E+E AE +++R RL + QELE I+++M R+ ++K + + D
Sbjct: 902 LQAETELYAEAEEMRVRLAAKKQELEEILHEMEARIEEEEERSQQLQAEKKKMQQQMLDL 961
Query: 2863 XXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQL 3042
+K D +D + LTT L
Sbjct: 962 EEQLEEEEAARQKLQLEKVTADGKIKKMEDDILIMEDQNNKLTKERKLLEERVSDLTTNL 1021
Query: 3043 LDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKM 3222
+ EE+AK+ K K + E+ + ELE L +E + + ELE+ KRKL E D + +AE
Sbjct: 1022 AEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKIKRKLEGESSDLHEQIAELQ 1081
Query: 3223 GKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARN 3402
++ EL QL K++EELQ L R ++E++ K++R++++ I +L+ED+E+E+ ARN
Sbjct: 1082 AQIAELKAQLAKKEEELQAALARLEDETSQKNNALKKIRELESHISDLQEDLESEKAARN 1141
Query: 3403 KAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIE 3582
KAE +R++ +LE +K ++ D +D Q+L +++++EV KRA+E+ T E +++
Sbjct: 1142 KAEKQKRDLSEELEALKTELEDTLDTTATQQELRAKREQEVTVLKRALEEETRTHEAQVQ 1201
Query: 3583 EQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRK 3762
E + K ++ VEEL +Q+EQ K+ ++ L+K + +++ AD+A EI L ++ D++ K+K
Sbjct: 1202 EMRQKHTQAVEELTEQLEQFKRAKANLDKTKQTLEKDNADLANEIRSLSQAKQDVEHKKK 1261
Query: 3763 IHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXX 3942
E L ++Q+ ++ + + L +++ + + E++++ + E E + + +AT
Sbjct: 1262 KLEVQLQDLQSKYSDGERVRTELNEKVHKLQIEVENVTSLLNEAESKNIKLTKDVATLGS 1321
Query: 3943 XXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGE 4122
TR K+ + RQLED+KN+L ++ +E + +LE+ I +
Sbjct: 1322 QLQDTQELLQEETRQKLNVTTKLRQLEDDKNSLQEQLDEEVEAKQNLERHISTLTIQLSD 1381
Query: 4123 ARRKAEE--SVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSME 4296
+++K +E + + +EE +KK R++E L +Q EE + +++ ++K ++QQEL+D ++
Sbjct: 1382 SKKKLQEFTATVETMEEGKKKLQREIESLTQQFEEKAASYDKLEKTKNRLQQELDDLVVD 1441
Query: 4297 LENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIM 4476
L+N R + EK+QKKF+ +AEE+ K +RD E R++ET+ LSL ++
Sbjct: 1442 LDNQRQLVSNLEKKQKKFDQMLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 1501
Query: 4477 KEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNL 4656
E EE +R + L+ E++D +S+KDD GKNVHELEK+KR+LE ++ +M+ Q+EELED L
Sbjct: 1502 LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRTLEQQVEEMKTQLEELEDEL 1561
Query: 4657 QIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGA 4836
Q AEDA+LRLEV QA+KS+ +R + +D + EEKRR LLKQ+ + E ELE+E++ ++ A
Sbjct: 1562 QAAEDAKLRLEVNMQAMKSQFERDLQARDEQNEEKRRQLLKQLHEHETELEDERKQRALA 1621
Query: 4837 VSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALL 5016
+ +KK+E + +LE Q++ AN+ +EE +YQ + ++AR A+E+I A
Sbjct: 1622 AAAKKKLEVDVKDLESQVDSANKAREEAIKQLRKLQAQMKDYQRDLDDARAAREEIFATA 1681
Query: 5017 READRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRA---KGGGISSEEKRRLE 5187
RE ++K + +EAE QL+E +ARKQ A G +EKRRLE
Sbjct: 1682 RENEKKAKNLEAELIQLQEDLAAAERARKQADLEKEEMAEELASANSGRTSLQDEKRRLE 1741
Query: 5188 AKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNR 5367
A+IAQ SN E D+ RKA Q EQ+ +L+ ER QK E +Q LER N+
Sbjct: 1742 ARIAQLEEELDEEHSNIETMSDRMRKAVQQAEQLNNELATERATAQKNENARQQLERQNK 1801
Query: 5368 DYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTT 5547
+ ++K+ E+E +S+ ++ +AALEAK+ LE+QL E +EK AA + R+ +K+L D
Sbjct: 1802 ELRSKLQEMEGAVKSKFKSTIAALEAKIASLEEQLEQEAREKQAAAKTLRQKDKKLKDAL 1861
Query: 5548 QQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANE 5727
Q EDE++ EQ K+ EK NL+ + L+RQL+EAE+E R R +QRE D+ ++N+
Sbjct: 1862 LQVEDERKQAEQYKDQAEKGNLRLKQLKRQLEEAEEESQRINANRRKLQRELDEATESND 1921
Query: 5728 QLTREL 5745
L RE+
Sbjct: 1922 ALGREV 1927
Score = 99.4 bits (246), Expect = 1e-18
Identities = 121/594 (20%), Positives = 237/594 (39%), Gaps = 32/594 (5%)
Frame = +1
Query: 4066 GLRAHLEKE---------IHAARQGAGEARRKAEESVNQQLEELR--KKNLRDVEHLQKQ 4212
G+ AHLE+E I Q G RKA QQL ++ ++N L+
Sbjct: 779 GVLAHLEEERDLKITDVIIAFQAQCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNW 838
Query: 4213 LEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFE---SQMAEERVAV 4383
K + L + ++E++ EL+ + + +E K+ E +Q+ EE+ +
Sbjct: 839 QWWRLFTKVKPLLQVTRQEEEMQAKDEELQRTKERQQKAEAELKELEQKHTQLCEEKNLL 898
Query: 4384 QKALLDRDAMSQELRDRETRVLSLLNEVDI----MKEHLEESDRVRRSLQQELQDSISNK 4551
Q+ L + E + R+ + E++ M+ +EE + + LQ E +
Sbjct: 899 QEKLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARIEEEEERSQQLQAEKKKMQQQM 958
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAI 4731
D + + E E A++ L+ E +++++ED++ I ED +L + L+
Sbjct: 959 LDLEEQLEEEEAARQKLQLEKVTADGKIKKMEDDILIMEDQNNKLTKERKLLEERVSDLT 1018
Query: 4732 SNKDVEAEEKRRGLLK-------QIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
+N E EEK + L K I +LE L+ E++ + ++K+E + +L +Q+
Sbjct: 1019 TNL-AEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKIKRKLEGESSDLHEQI 1077
Query: 4891 EVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLR 5070
E + + E + A ED + A +K R +E+ L+
Sbjct: 1078 A-------ELQAQIAELKAQLAKKEEELQAALARLEDETSQKNNALKKIRELESHISDLQ 1130
Query: 5071 EANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAI 5250
E E AR + SEE L+ ++ Q EL
Sbjct: 1131 EDLESEKAARNKAEKQKRDL-----------SEELEALKTELEDTLDTTATQQ---ELRA 1176
Query: 5251 DKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQM 5430
++++ V ++R L ++T + ++ + + + EL + RA+
Sbjct: 1177 KREQEVTV----------LKRALEEETRTHEAQVQEMRQKHTQAVEELTEQLEQFKRAK- 1225
Query: 5431 AALEAKVQYLE-------DQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAK 5589
A L+ Q LE +++ Q K ++LE +L D ++ D +R +
Sbjct: 1226 ANLDKTKQTLEKDNADLANEIRSLSQAKQDVEHKKKKLEVQLQDLQSKYSDGERVRTELN 1285
Query: 5590 ELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
E + K ++ N+ L+EAE + + + + D + ++ TR+ +N
Sbjct: 1286 EKVHKLQIEVENVTSLLNEAESKNIKLTKDVATLGSQLQDTQELLQEETRQKLN 1339
>gi|3915778|sp|P10587|MYHB_CHICK Myosin heavy chain, gizzard smooth
muscle
Length = 1979
Score = 1777 bits (4602), Expect = 0.0
Identities = 928/1926 (48%), Positives = 1304/1926 (67%), Gaps = 13/1926 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
D ++L V + V +P A W+ +KL WVP + GF SIK E DEV VEL + ++V
Sbjct: 9 DEKFLFVDKNFVNNPLAQADWSAKKLVWVPSEKHGFEAASIKEEKGDEVTVELQENGKKV 68
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
T+S+DD+QK NPPKF K+EDM+ELT LNEASVLHNL++RY+S LIYTYSGLFCVVINPYK
Sbjct: 69 TLSKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVINPYK 128
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
+LPIYSE +I+ +KGKKRHEMPPHI+AIADTAYRSMLQ+REDQSILCTGESGAGKTENTK
Sbjct: 129 QLPIYSEKIIDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTK 188
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVIQYLA VA + + K +I Q P GELE QLLQANPILEAFGN+KTVK
Sbjct: 189 KVIQYLAVVASSHKGKK-----DTSITQGPSFS--YGELEKQLLQANPILEAFGNAKTVK 241
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
NDNSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFY ++ G S +
Sbjct: 242 NDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQAKDERTFHIFYYLIAGASEQM 301
Query: 907 KSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLL 1086
+++ LLEG +NY FL N + +P D + F T+ +M IMGF ++E +SI+RVVS+VL
Sbjct: 302 RNDLLLEGFNNYTFLSNGHVPIPAQQDDEMFQETLEAMTIMGFTEEEQTSILRVVSSVLQ 361
Query: 1087 LGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQE 1266
LGN+ F +E+ +DQA + D+ QKVCHL+G+ V + ++ L PRIKVGR+ V KAQ +E
Sbjct: 362 LGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKE 421
Query: 1267 QAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQIC 1446
QA+FA+EA+AKA +ERLF+W++TR+NK+LD+T RQGASF+GILDIAGFEIF+INSFEQ+C
Sbjct: 422 QADFAIEALAKAKFERLFRWILTRVNKALDKTKRQGASFLGILDIAGFEIFEINSFEQLC 481
Query: 1447 INYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALL 1617
INYTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP I+LIE+P GVLALL
Sbjct: 482 INYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPTNPPGVLALL 541
Query: 1618 DEECLFPKANDKSFVEKLQKTHNKHPKF-IVPDMRSKSHFAVVHYAGRVDYSADQWLMKN 1794
DEEC FPKA D SFVEKL + H KF ++ K+ F ++HYAG+V Y+A WL KN
Sbjct: 542 DEECWFPKATDTSFVEKLIQEQGNHAKFQKSKQLKDKTEFCILHYAGKVTYNASAWLTKN 601
Query: 1795 MDPLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQ 1962
MDPLN+NV L+ S+D FVA +WKD + G+ A+M E++ +++KGMFRTV Q
Sbjct: 602 MDPLNDNVTSLLNQSSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQ 661
Query: 1963 LHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGF 2142
L+KEQLTKLMTTLRNT+P+FVRCIIPNHEK++GK++++LVLEQLRCNGVLEGIRICRQGF
Sbjct: 662 LYKEQLTKLMTTLRNTNPNFVRCIIPNHEKRAGKLDAHLVLEQLRCNGVLEGIRICRQGF 721
Query: 2143 PNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVL 2322
PNR+ FQEFR RYEIL + IPK F+DGK++ MI AL++D NLYRIGQSK+FFRTGVL
Sbjct: 722 PNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVL 781
Query: 2323 AHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWW 2502
AHLEEERDLK+T +I+ FQAQCRG+L+R+ + N AYLKLRNWQWW
Sbjct: 782 AHLEEERDLKITDVIIAFQAQCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWW 841
Query: 2503 RLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQ 2682
RLFTKVKPLLQVTR ++E++AKD+EL+ TKER K E + +E E+K Q+ E+ ++QE+
Sbjct: 842 RLFTKVKPLLQVTRQEEEMQAKDEELQRTKERQQKAEAELKELEQKHTQLCEEKNLLQEK 901
Query: 2683 LQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDX 2862
LQ E+E AE +++R RL + QELE I+++M R+ ++K + + D
Sbjct: 902 LQAETELYAEAEEMRVRLAAKKQELEEILHEMEARIEEEEERSQQLQAEKKKMQQQMLDL 961
Query: 2863 XXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQL 3042
+K D +D + LTT L
Sbjct: 962 EEQLEEEEAARQKLQLEKVTADGKIKKMEDDILIMEDQNNKLTKERKLLEERVSDLTTNL 1021
Query: 3043 LDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKM 3222
+ EE+AK+ K K + E+ + ELE L +E + + ELE+ KRKL E D + +AE
Sbjct: 1022 AEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKIKRKLEGESSDLHEQIAELQ 1081
Query: 3223 GKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARN 3402
++ EL QL K++EELQ L R ++E++ K++R++++ I +L+ED+E+E+ ARN
Sbjct: 1082 AQIAELKAQLAKKEEELQAALARLEDETSQKNNALKKIRELESHISDLQEDLESEKAARN 1141
Query: 3403 KAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIE 3582
KAE +R++ +LE +K ++ D +D Q+L +++++EV KRA+E+ T E +++
Sbjct: 1142 KAEKQKRDLSEELEALKTELEDTLDTTATQQELRAKREQEVTVLKRALEEETRTHEAQVQ 1201
Query: 3583 EQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRK 3762
E + K ++ VEEL +Q+EQ K+ ++ L+K + +++ AD+A EI L ++ D++ K+K
Sbjct: 1202 EMRQKHTQAVEELTEQLEQFKRAKANLDKTKQTLEKDNADLANEIRSLSQAKQDVEHKKK 1261
Query: 3763 IHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXX 3942
E L ++Q+ ++ + + L +++ + + E++++ + E E + + +AT
Sbjct: 1262 KLEVQLQDLQSKYSDGERVRTELNEKVHKLQIEVENVTSLLNEAESKNIKLTKDVATLGS 1321
Query: 3943 XXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGE 4122
TR K+ + RQLED+KN+L ++ +E + +LE+ I +
Sbjct: 1322 QLQDTQELLQEETRQKLNVTTKLRQLEDDKNSLQEQLDEEVEAKQNLERHISTLTIQLSD 1381
Query: 4123 ARRKAEE--SVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSME 4296
+++K +E + + +EE +KK R++E L +Q EE + +++ ++K ++QQEL+D ++
Sbjct: 1382 SKKKLQEFTATVETMEEGKKKLQREIESLTQQFEEKAASYDKLEKTKNRLQQELDDLVVD 1441
Query: 4297 LENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIM 4476
L+N R + EK+QKKF+ +AEE+ K +RD E R++ET+ LSL ++
Sbjct: 1442 LDNQRQLVSNLEKKQKKFDQMLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 1501
Query: 4477 KEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNL 4656
E EE +R + L+ E++D +S+KDD GKNVHELEK+KR+LE ++ +M+ Q+EELED L
Sbjct: 1502 LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRTLEQQVEEMKTQLEELEDEL 1561
Query: 4657 QIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGA 4836
Q AEDA+LRLEV QA+KS+ +R + +D + EEKRR LLKQ+ + E ELE+E++ ++ A
Sbjct: 1562 QAAEDAKLRLEVNMQAMKSQFERDLQARDEQNEEKRRQLLKQLHEHETELEDERKQRALA 1621
Query: 4837 VSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALL 5016
+ +KK+E + +LE Q++ AN+ +EE +YQ + ++AR A+E+I A
Sbjct: 1622 AAAKKKLEVDVKDLESQVDSANKAREEAIKQLRKLQAQMKDYQRDLDDARAAREEIFATA 1681
Query: 5017 READRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRA---KGGGISSEEKRRLE 5187
RE ++K + +EAE QL+E +ARKQ A G +EKRRLE
Sbjct: 1682 RENEKKAKNLEAELIQLQEDLAAAERARKQADLEKEEMAEELASANSGRTSLQDEKRRLE 1741
Query: 5188 AKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNR 5367
A+IAQ SN E D+ RKA Q EQ+ +L+ ER QK E +Q LER N+
Sbjct: 1742 ARIAQLEEELDEEHSNIETMSDRMRKAVQQAEQLNNELATERATAQKNENARQQLERQNK 1801
Query: 5368 DYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTT 5547
+ ++K+ E+E +S+ ++ +AALEAK+ LE+QL E +EK AA + R+ +K+L D
Sbjct: 1802 ELRSKLQEMEGAVKSKFKSTIAALEAKIASLEEQLEQEAREKQAAAKTLRQKDKKLKDAL 1861
Query: 5548 QQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANE 5727
Q EDE++ EQ K+ EK NL+ + L+RQL+EAE+E R R +QRE D+ ++N+
Sbjct: 1862 LQVEDERKQAEQYKDQAEKGNLRLKQLKRQLEEAEEESQRINANRRKLQRELDEATESND 1921
Query: 5728 QLTREL 5745
L RE+
Sbjct: 1922 ALGREV 1927
Score = 99.4 bits (246), Expect = 1e-18
Identities = 121/594 (20%), Positives = 237/594 (39%), Gaps = 32/594 (5%)
Frame = +1
Query: 4066 GLRAHLEKE---------IHAARQGAGEARRKAEESVNQQLEELR--KKNLRDVEHLQKQ 4212
G+ AHLE+E I Q G RKA QQL ++ ++N L+
Sbjct: 779 GVLAHLEEERDLKITDVIIAFQAQCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNW 838
Query: 4213 LEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFE---SQMAEERVAV 4383
K + L + ++E++ EL+ + + +E K+ E +Q+ EE+ +
Sbjct: 839 QWWRLFTKVKPLLQVTRQEEEMQAKDEELQRTKERQQKAEAELKELEQKHTQLCEEKNLL 898
Query: 4384 QKALLDRDAMSQELRDRETRVLSLLNEVDI----MKEHLEESDRVRRSLQQELQDSISNK 4551
Q+ L + E + R+ + E++ M+ +EE + + LQ E +
Sbjct: 899 QEKLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARIEEEEERSQQLQAEKKKMQQQM 958
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAI 4731
D + + E E A++ L+ E +++++ED++ I ED +L + L+
Sbjct: 959 LDLEEQLEEEEAARQKLQLEKVTADGKIKKMEDDILIMEDQNNKLTKERKLLEERVSDLT 1018
Query: 4732 SNKDVEAEEKRRGLLK-------QIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
+N E EEK + L K I +LE L+ E++ + ++K+E + +L +Q+
Sbjct: 1019 TNL-AEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKIKRKLEGESSDLHEQI 1077
Query: 4891 EVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLR 5070
E + + E + A ED + A +K R +E+ L+
Sbjct: 1078 A-------ELQAQIAELKAQLAKKEEELQAALARLEDETSQKNNALKKIRELESHISDLQ 1130
Query: 5071 EANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAI 5250
E E AR + SEE L+ ++ Q EL
Sbjct: 1131 EDLESEKAARNKAEKQKRDL-----------SEELEALKTELEDTLDTTATQQ---ELRA 1176
Query: 5251 DKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQM 5430
++++ V ++R L ++T + ++ + + + EL + RA+
Sbjct: 1177 KREQEVTV----------LKRALEEETRTHEAQVQEMRQKHTQAVEELTEQLEQFKRAK- 1225
Query: 5431 AALEAKVQYLE-------DQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAK 5589
A L+ Q LE +++ Q K ++LE +L D ++ D +R +
Sbjct: 1226 ANLDKTKQTLEKDNADLANEIRSLSQAKQDVEHKKKKLEVQLQDLQSKYSDGERVRTELN 1285
Query: 5590 ELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
E + K ++ N+ L+EAE + + + + D + ++ TR+ +N
Sbjct: 1286 EKVHKLQIEVENVTSLLNEAESKNIKLTKDVATLGSQLQDTQELLQEETRQKLN 1339
>gi|11276949|pir||A59282 nonmuscle myosin II heavy chain A - African
clawed frog
gi|3660672|gb|AAC83556.1| nonmuscle myosin II heavy chain A [Xenopus
laevis]
Length = 1964
Score = 1776 bits (4601), Expect = 0.0
Identities = 920/1925 (47%), Positives = 1295/1925 (66%), Gaps = 14/1925 (0%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL V R V +P A WA +KL WVP + GF SIK E DE +VEL + ++ +
Sbjct: 8 KYLYVDRNFVNNPLAQADWAAKKLVWVPSEKNGFEAASIKEEVGDEAIVELAENGKKAKV 67
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDMSEL LNEASVLHNLK+RYYS LIYTYSGLFCVVINPYK L
Sbjct: 68 NKDDIQKMNPPKFSKVEDMSELACLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNL 127
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYSE+++E +KGKKRHEMPPHI+AI DTAYRSM+Q+REDQSILCTGESGAGKTENTKKV
Sbjct: 128 PIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKV 187
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
IQYLA+VA + ++K GELE QLLQANPILEAFGN+KTVKND
Sbjct: 188 IQYLAYVATSHKSKKDQ-----------------GELERQLLQANPILEAFGNAKTVKND 230
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFY ++ G KS
Sbjct: 231 NSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKDERTFHIFYYLMSGAGEHLKS 290
Query: 913 EYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 1092
+ LLE + YRFL N +T+P D F T+ +M+IMGF D+E + ++RVVSAVL LG
Sbjct: 291 DLLLEAYNKYRFLSNGHVTIPGQLDKDLFQETMEAMKIMGFTDEEQTGLLRVVSAVLQLG 350
Query: 1093 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA 1272
N+ F +E+ +DQA + D+ QKVCHLLG+ V + + L PRIKVGR+FV KAQ +EQA
Sbjct: 351 NIAFKKERNTDQASMPDNTAAQKVCHLLGINVNDFTRGILLPRIKVGRDFVQKAQTKEQA 410
Query: 1273 EFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICIN 1452
+FA+EA+AKASYER+F+WLV R+NK+LD+T RQGASFIGILDIAGFEIF++NSFEQ+CIN
Sbjct: 411 DFAIEALAKASYERMFRWLVMRVNKALDKTKRQGASFIGILDIAGFEIFELNSFEQLCIN 470
Query: 1453 YTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDE 1623
YTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP IDLIE+P G+LALLDE
Sbjct: 471 YTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPAGPPGILALLDE 530
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMD 1800
EC FPKA DKSFVEK+ + H KF P ++ K+ F+++HYAGRVDY AD+WL+KNMD
Sbjct: 531 ECWFPKATDKSFVEKVVQEQGSHSKFQKPKQLKDKADFSIIHYAGRVDYKADEWLLKNMD 590
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQLH 1968
PLN+NV L+ S+D FV+ +WKD + G+ A M++TA ++RKGMFRTV QL+
Sbjct: 591 PLNDNVATLLNQSSDKFVSELWKDVDRIVGLDQVAGMSDTALPGAFKTRKGMFRTVGQLY 650
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
KEQL+KLM TLRNT+P+FVRCIIPNHEKKSGK++++LVL+QLRCNGVLEGIRICRQGFPN
Sbjct: 651 KEQLSKLMATLRNTNPNFVRCIIPNHEKKSGKLDAHLVLDQLRCNGVLEGIRICRQGFPN 710
Query: 2149 RVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAH 2328
RV FQEFR RYEILTP+ IPK F+DGK++ MI AL++D+NLYRIGQSKVFFR+GVLAH
Sbjct: 711 RVVFQEFRQRYEILTPNAIPKGFMDGKQACVLMIRALELDSNLYRIGQSKVFFRSGVLAH 770
Query: 2329 LEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRL 2508
LEEERDLK+T +I++FQA CRG+L+R+ + N AYLKLRNWQWWRL
Sbjct: 771 LEEERDLKITDVIISFQACCRGYLARKAFARRQQQLTAMKVIQRNCAAYLKLRNWQWWRL 830
Query: 2509 FTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQ 2688
FTKVKPLLQ R D+E+ AK+ EL+ K+ + E E E + E+ +QEQLQ
Sbjct: 831 FTKVKPLLQANRFDEELHAKEVELQKIKDLQVSSEQKVSEMENVQMMLQQEKMQLQEQLQ 890
Query: 2689 QESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXX 2868
E E AE +++R RL + QELE I++D+ R+ ++K + + +
Sbjct: 891 AEIELCAEAEEMRARLANKKQELEEILHDLESRVEEEEERCQILQTEKKKMQQNIVELEE 950
Query: 2869 XXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLD 3048
+K + +D TT L +
Sbjct: 951 QLEEEEAARQKLQLEKVTAEAKMKKLEEDVLVLEDQNTKLGKEKKLYEERIAEFTTNLTE 1010
Query: 3049 HEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGK 3228
EE++K K K + E + +LE+ L RE + + ELE+ +RKL + D D +AE +
Sbjct: 1011 EEEKSKSLAKLKNKHETMISDLEERLRREEKQRQELEKTRRKLEGDSTDLHDQIAELQAQ 1070
Query: 3229 VEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKA 3408
+ EL QL K++EELQ L R +EE+A L K++R++++ I EL+ED+E+ER ARNKA
Sbjct: 1071 IAELKLQLAKKEEELQAALARAEEEAAQKNLALKKIRELESQIGELQEDLESERAARNKA 1130
Query: 3409 EMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQ 3588
E +R++ +LE +K ++ D +D Q+L +++++EV K+ +E T EG+I+E
Sbjct: 1131 EKQKRDLGEELEALKTELEDTLDSTATQQELRTKREQEVTHLKKTLEDEARTHEGQIQEI 1190
Query: 3589 KAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIH 3768
+ K S+ VEEL +Q+EQ K+ + LEK + + ER ++A E+ L + D + KRK
Sbjct: 1191 RQKHSQAVEELSEQLEQTKRLKGNLEKAKQALEGERNELANEVKTLLQGKGDSEHKRKKV 1250
Query: 3769 EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXX 3948
EA L E+Q + E D + L ++ R + ELD++N + + + + + +T
Sbjct: 1251 EAQLQELQVKVTEGDRVRSELSEKANRLQVELDNVNSLLSQSDSKSIKLGKDFSTLESQF 1310
Query: 3949 XXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEAR 4128
TR K++ + +Q+EDEKN LL++ EE E + +L K+I + + +
Sbjct: 1311 QDAQELLQEETRQKLSFSTKLKQMEDEKNGLLEQLEEEEEAKKNLCKQISTLQSQMTDMK 1370
Query: 4129 RKAEESVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
+K +E+V + +EEL+KK +D+E + ++ EE A +++ ++K ++QQEL+D S++L+
Sbjct: 1371 KKMDENVGSLETVEELKKKLQKDLEAVNQRFEEKAAAYDKLEKTKTRLQQELDDISVDLD 1430
Query: 4303 NVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKE 4482
+ R + EK+QKKF+ + EE+ K +RD E R++ET+ L+L ++ E
Sbjct: 1431 HQRQIVSNLEKKQKKFDQLLGEEKAISAKYADERDRSEAEAREKETKALALARALEEALE 1490
Query: 4483 HLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQI 4662
E +R+ + L+ E++D +S+KDD GK+VHELEK+KR+LE + +M+ Q+EELED LQ
Sbjct: 1491 AKAELERLNKQLRTEMEDLVSSKDDVGKSVHELEKSKRALEQQAEEMKTQLEELEDELQA 1550
Query: 4663 AEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVS 4842
EDA+LRLEV QA+K++ +R + +D ++E+K++ L++Q++++E ELE+E++ +S AV+
Sbjct: 1551 TEDAKLRLEVNLQAMKAQFERDLQGRDEQSEDKKKQLVRQVKEMEAELEDERKQRSLAVA 1610
Query: 4843 HRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLRE 5022
RKK+E + +LE Q++ +N+ +E+ +YQ E E+ R +++DI + +E
Sbjct: 1611 ARKKLEMDLKDLEGQIDSSNKNREDAIKQLRKLQAQIKDYQRELEDTRASRDDILSQSKE 1670
Query: 5023 ADRKFRAVEAE----REQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEA 5190
+++K +++EAE +E+L A G QA+++ K G ++ EEKRRLE+
Sbjct: 1671 SEKKLKSMEAEMIHMQEELAAAERGKRQAQQERDELADEIANSSGK-GALALEEKRRLES 1729
Query: 5191 KIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRD 5370
+IAQ Q N EL D+ +K+ +Q++Q+ TDL+ ER+ QK E +Q ++R N++
Sbjct: 1730 RIAQLEEELEEEQGNTELVNDRLKKSTLQIDQLNTDLTAERSNAQKNENARQQMDRQNKE 1789
Query: 5371 YKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQ 5550
K K+ E+E +S+ +A + ALEAK+ LE+QL+ E +E+ A++ RR EK+L D
Sbjct: 1790 LKTKLQEMEGIVKSKFKANITALEAKIAQLEEQLDTETKERQNASKQVRRTEKKLKDVLM 1849
Query: 5551 QFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQ 5730
EDE+R +EQ K+ EK+N++ + L+RQ++EAE+E R R +QRE +D + E
Sbjct: 1850 LVEDERRNSEQYKDQAEKNNVRMKQLKRQVEEAEEEAQRANAMRRKLQRELEDATETAEI 1909
Query: 5731 LTREL 5745
+ RE+
Sbjct: 1910 MNREV 1914
>gi|20137006|ref|NP_071855.1| myosin heavy chain IX [Mus musculus]
gi|17978023|emb|CAC85955.1| nonmuscle heavy chain myosin II-A [Mus
musculus]
Length = 1960
Score = 1774 bits (4594), Expect = 0.0
Identities = 917/1924 (47%), Positives = 1287/1924 (66%), Gaps = 13/1924 (0%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL V + + +P A WA +KL WVP GF S+K E +E +VELV+ ++V +
Sbjct: 8 KYLYVDKNFINNPLAQADWAAKKLVWVPSSKNGFEPASLKEEVGEEAIVELVENGKKVKV 67
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDM+ELT LNEASVLHNLK+RYYS LIYTYSGLFCVVINPYK L
Sbjct: 68 NKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNL 127
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYSE+++E +KGKKRHEMPPHI+AI DTAYRSM+Q+REDQSILCTGESGAGKTENTKKV
Sbjct: 128 PIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKV 187
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
IQYLAHVA + ++K GELE QLLQANPILEAFGN+KTVKND
Sbjct: 188 IQYLAHVASSHKSKKDQ-----------------GELERQLLQANPILEAFGNAKTVKND 230
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA++ER+FHIFY +L G K+
Sbjct: 231 NSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKT 290
Query: 913 EYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 1092
+ LLE + YRFL N +T+P D F T+ +MRIMG +DE ++RV+S VL LG
Sbjct: 291 DLLLEPYNKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPEDEQMGLLRVISGVLQLG 350
Query: 1093 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA 1272
N+ F +E+ +DQA + D+ QKV HLLG+ V + + L PRIKVGR++V KAQ +EQA
Sbjct: 351 NIAFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQA 410
Query: 1273 EFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICIN 1452
+FA+EA+AKA+YER+F+WLV RINK+LD+T RQGASFIGILDIAGFEIFD+NSFEQ+CIN
Sbjct: 411 DFAIEALAKATYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCIN 470
Query: 1453 YTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDE 1623
YTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP IDLIEKP G+LALLDE
Sbjct: 471 YTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDE 530
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMD 1800
EC FPKA DKSFVEK+ + HPKF P ++ K+ F ++HYAG+VDY AD+WLMKNMD
Sbjct: 531 ECWFPKATDKSFVEKVVQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMD 590
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQLH 1968
PLN+N+ L+ S+D FV+ +WKD + G+ A M+ETA ++RKGMFRTV QL+
Sbjct: 591 PLNDNIATLLHQSSDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLY 650
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
KEQL KLM TLRNT+P+FVRCIIPNHEKK+GK++ +LVL+QLRCNGVLEGIRICRQGFPN
Sbjct: 651 KEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPN 710
Query: 2149 RVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAH 2328
RV FQEFR RYEILTP+ IPK F+DGK++ MI AL++D+NLYRIGQSKVFFR GVLAH
Sbjct: 711 RVVFQEFRQRYEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAH 770
Query: 2329 LEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRL 2508
LEEERDLK+T +I+ FQA CRG+L+R+ + N AYL+LRNWQWWRL
Sbjct: 771 LEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLRLRNWQWWRL 830
Query: 2509 FTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQ 2688
FTKVKPLL R +DE+ AK+ EL +E+ L E+ E E Q++ E+ +QEQLQ
Sbjct: 831 FTKVKPLLNSIRHEDELLAKEAELTKVREKHLAAENRLTEMETMQSQLMAEKLQLQEQLQ 890
Query: 2689 QESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXX 2868
E+E AE +++R RL + QELE I +D+ R+ ++K + +++
Sbjct: 891 AETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQYLQAEKKKMQQNIQELEE 950
Query: 2869 XXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLD 3048
+K + +D TT L++
Sbjct: 951 QLEEEESARQKLQLEKVTTEAKLKKLEEDQIIMEDQNCKLAKEKKLLEDRVAEFTTNLME 1010
Query: 3049 HEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGK 3228
EE++K K K + E + +LE+ L RE + + ELE+ +RKL + D D +AE +
Sbjct: 1011 EEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQ 1070
Query: 3229 VEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKA 3408
+ EL QL K++EELQ L R +EE+A + K++R+++T I EL+ED+E+ER +RNKA
Sbjct: 1071 IAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELETQISELQEDLESERASRNKA 1130
Query: 3409 EMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQ 3588
E +R++ +LE +K ++ D +D Q+L S++++EV+ K+ +E T E +I+E
Sbjct: 1131 EKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVSILKKTLEDEAKTHEAQIQEM 1190
Query: 3589 KAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIH 3768
+ K S+ VEEL DQ+EQ K+ ++ LEK + + ER ++A E+ L + D + KRK
Sbjct: 1191 RQKHSQAVEELADQLEQTKRVKATLEKAKQTLENERGELANEVKALLQGKGDSEHKRKKV 1250
Query: 3769 EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXX 3948
EA L E+Q +E + + L D++ + + ELD + + + + + + + +
Sbjct: 1251 EAQLQELQVKFSEGERVRTELADKVTKLQVELDSVTGLLSQSDSKSSKLTKDFSALESQL 1310
Query: 3949 XXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEAR 4128
R K++ + +Q+EDEKN+ ++ EE E + +LEK+I + +
Sbjct: 1311 QDTQELLQEENRQKLSLSTKLKQMEDEKNSFREQLEEEEEAKRNLEKQIATLHAQVTDMK 1370
Query: 4129 RKAEESVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
+K E+ V + EE +++ +D+E L ++LEE A +++ ++K ++QQEL+D ++L+
Sbjct: 1371 KKMEDGVGCLETAEEAKRRLQKDLEGLSQRLEEKVAAYDKLEKTKTRLQQELDDLLVDLD 1430
Query: 4303 NVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKE 4482
+ R S + EK+QKKF+ +AEE+ K +RD E R++ET+ LSL ++ E
Sbjct: 1431 HQRQSVSNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAME 1490
Query: 4483 HLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQI 4662
E +R+ + + E++D +S+KDD GK+VHELEK+KR+LE ++ +M+ Q+EELED LQ
Sbjct: 1491 QKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQA 1550
Query: 4663 AEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVS 4842
EDA+LRLEV QA+K++ +R + +D ++EEK++ L++Q+R++E ELE+E++ +S A++
Sbjct: 1551 TEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAMA 1610
Query: 4843 HRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLRE 5022
RKK+E + +LE ++ AN+ +EE + E ++ R ++E+I A +E
Sbjct: 1611 ARKKLEMDLKDLEAHIDTANKNREEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKE 1670
Query: 5023 ADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKG---GGISSEEKRRLEAK 5193
++K +++EAE QL+E +A++Q A G ++ EEKRRLEA+
Sbjct: 1671 NEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEAR 1730
Query: 5194 IAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDY 5373
IA Q N EL D+ +KA +Q++QI TDL++ER+ QK E +Q LER N++
Sbjct: 1731 IALLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKEL 1790
Query: 5374 KAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQ 5553
KAK+ E+ES +S+ +A +AALEAK+ LE+QL+ E +E+ AA++ RR EK+L D Q
Sbjct: 1791 KAKLQEMESAVKSKYKASIAALEAKIAQLEEQLDNETKERQAASKQVRRTEKKLKDVLLQ 1850
Query: 5554 FEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQL 5733
EDE+R EQ K+ +K++ + + L+RQL+EAE+E R R +QRE +D + + +
Sbjct: 1851 VEDERRNAEQFKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAM 1910
Query: 5734 TREL 5745
RE+
Sbjct: 1911 NREV 1914
>gi|27529744|dbj|BAA74889.2| KIAA0866 protein [Homo sapiens]
Length = 1984
Score = 1769 bits (4583), Expect = 0.0
Identities = 916/1926 (47%), Positives = 1303/1926 (67%), Gaps = 13/1926 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
D ++L V + + P A WA ++L WVP + +GF SIK E DEV+VELV+ ++V
Sbjct: 22 DEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKV 81
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
T+ +DD+QK NPPKF K+EDM+ELT LNEASVLHNL++RY+S LIYTYSGLFCVV+NPYK
Sbjct: 82 TVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYK 141
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
LPIYSE +++ +KGKKRHEMPPHI+AIADTAYRSMLQ+REDQSILCTGESGAGKTENTK
Sbjct: 142 HLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTK 201
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVIQYLA VA + + K + GELE QLLQANPILEAFGN+KTVK
Sbjct: 202 KVIQYLAVVASSHKGKKDTSIT--------------GELEKQLLQANPILEAFGNAKTVK 247
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
NDNSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFY ++ G K
Sbjct: 248 NDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKM 307
Query: 907 KSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLL 1086
+S+ LLEG +NY FL N + +P D + F T+ +M IMGF+++E SI++VVS+VL
Sbjct: 308 RSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQ 367
Query: 1087 LGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQE 1266
LGN+ F +E+ +DQA + D+ QKVCHL+G+ V + ++ L PRIKVGR+ V KAQ +E
Sbjct: 368 LGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKE 427
Query: 1267 QAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQIC 1446
QA+FAVEA+AKA+YERLF+W++TR+NK+LD+THRQGASF+GILDIAGFEIF++NSFEQ+C
Sbjct: 428 QADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLC 487
Query: 1447 INYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEK---PMGVLALL 1617
INYTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP I+LIE+ P GVLALL
Sbjct: 488 INYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALL 547
Query: 1618 DEECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKN 1794
DEEC FPKA DKSFVEKL HPKF P ++ K+ F+++HYAG+VDY+A WL KN
Sbjct: 548 DEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKN 607
Query: 1795 MDPLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQ 1962
MDPLN+NV L+ S+D FVA +WKD + G+ A+M E++ +++KGMFRTV Q
Sbjct: 608 MDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQ 667
Query: 1963 LHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGF 2142
L+KEQL KLMTTLRNT+P+FVRCIIPNHEK+SGK+++ LVLEQLRCNGVLEGIRICRQGF
Sbjct: 668 LYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGF 727
Query: 2143 PNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVL 2322
PNR+ FQEFR RYEIL + IPK F+DGK++ MI AL++D NLYRIGQSK+FFRTGVL
Sbjct: 728 PNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVL 787
Query: 2323 AHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWW 2502
AHLEEERDLK+T +IM FQA CRG+L+R+ + N AYLKLRNWQWW
Sbjct: 788 AHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWW 847
Query: 2503 RLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQ 2682
RLFTKVKPLLQVTR ++E++AK+DEL+ TKER K E++ +E E+K Q+ E+ ++QEQ
Sbjct: 848 RLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQ 907
Query: 2683 LQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDX 2862
LQ E+E AE +++R RL + QELE I+++M RL R+K + + D
Sbjct: 908 LQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDL 967
Query: 2863 XXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQL 3042
+K + D + LTT L
Sbjct: 968 EEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNL 1027
Query: 3043 LDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKM 3222
+ EE+AK+ K K + E+ + ELE L +E + + ELE+ KRKL + D + +A+
Sbjct: 1028 AEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQ 1087
Query: 3223 GKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARN 3402
++ EL QL K++EELQ L R D+E A K++R+++ I +L+ED+++ER ARN
Sbjct: 1088 AQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARN 1147
Query: 3403 KAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIE 3582
KAE +R++ +LE +K ++ D +D Q+L +++++EV K+A+++ + E +++
Sbjct: 1148 KAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQ 1207
Query: 3583 EQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRK 3762
E + K ++ VEEL +Q+EQ K+ ++ L+K + ++E AD+A E+ +L ++ +++ K+K
Sbjct: 1208 EMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKK 1267
Query: 3763 IHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXX 3942
EA + E+Q+ ++ + + L D++ + ++E++ + + E E + + +A+
Sbjct: 1268 KLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS 1327
Query: 3943 XXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGE 4122
TR K+ + RQLE+E+N+L D+ +E + +LE+ I +
Sbjct: 1328 QLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSD 1387
Query: 4123 ARRKAEE--SVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSME 4296
+++K ++ S + LEE +K+ +++E+L +Q EE A +++ ++K ++QQEL+D ++
Sbjct: 1388 SKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1447
Query: 4297 LENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIM 4476
L+N R + EK+Q+KF+ +AEE+ K +RD E R++ET+ LSL ++
Sbjct: 1448 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 1507
Query: 4477 KEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNL 4656
E EE +R + L+ E++D +S+KDD GKNVHELEK+KR+LE ++ +M+ Q+EELED L
Sbjct: 1508 LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDEL 1567
Query: 4657 QIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGA 4836
Q EDA+LRLEV QALK + +R + +D + EEKRR L +Q+ + E ELE+E++ ++ A
Sbjct: 1568 QATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALA 1627
Query: 4837 VSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALL 5016
+ +KK+E + +LE Q + A + +EE ++Q E E+AR ++++I A
Sbjct: 1628 AAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATA 1687
Query: 5017 READRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRA---KGGGISSEEKRRLE 5187
+E ++K +++EA+ QL+E +ARKQ A G +EKRRLE
Sbjct: 1688 KENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE 1747
Query: 5188 AKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNR 5367
A+IAQ Q N E D+ RKA Q EQ++ +L+ ER+ QK E+ +Q LER N+
Sbjct: 1748 ARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNK 1807
Query: 5368 DYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTT 5547
+ ++K+ E+E +S+ ++ +AALEAK+ LE+Q+ E +EK AA ++ ++ +K+L +
Sbjct: 1808 ELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEIL 1867
Query: 5548 QQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANE 5727
Q EDE++ EQ KE EK N + + L+RQL+EAE+E R R +QRE D+ ++NE
Sbjct: 1868 LQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNE 1927
Query: 5728 QLTREL 5745
+ RE+
Sbjct: 1928 AMGREV 1933
Score = 93.2 bits (230), Expect = 7e-17
Identities = 110/537 (20%), Positives = 206/537 (37%), Gaps = 25/537 (4%)
Frame = +1
Query: 4216 EESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKAL 4395
EE AKE LQ K+ QQ+ E+ ELE QK SQ+ EE+ +Q+ L
Sbjct: 863 EEEMQAKEDELQKTKERQQKAENELKELE------------QK--HSQLTEEKNLLQEQL 908
Query: 4396 LDRDAMSQELRDRETRVLSLLNEVDI----MKEHLEESDRVRRSLQQELQDSISNKDDFG 4563
+ E + R+ + E++ M+ LEE + + LQ E + D
Sbjct: 909 QAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLE 968
Query: 4564 KNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
+ + E E A++ L+ E ++++LED + + +D +L + L+ +N
Sbjct: 969 EQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNL- 1027
Query: 4744 VEAEEKRRGLLK-------QIRDLENELENEKRGKSGAVSHRKKIEN------------- 4863
E EEK + L K I +LE L+ E++ + ++K+E
Sbjct: 1028 AEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQ 1087
Query: 4864 -QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFR 5040
QI EL+ QL + +EE + ++ R+ + I+ L + D +
Sbjct: 1088 AQIAELKMQLA---KKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERA 1144
Query: 5041 AVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXX 5220
A +Q R+ E L + + + KR E + +
Sbjct: 1145 ARNKAEKQKRDLGEELEALKTELEDTLDSTATQQ------ELRAKREQEVTVLKKALDEE 1198
Query: 5221 XXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES 5400
++ +Q+ AQ +E++T L + + KQ+LE+ N D
Sbjct: 1199 TRSHEAQVQEMRQKHAQA-VEELTEQLEQFKRAKANLDKNKQTLEKENAD---------- 1247
Query: 5401 GAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANE 5580
L +L V GQ K ++LE ++ + + D +RA
Sbjct: 1248 -------------------LAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 1288
Query: 5581 QAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
+ + + K + ++ L+EAE + + ++ + D + ++ TR+ +N
Sbjct: 1289 ELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLN 1345
>gi|13124875|ref|NP_074035.1| smooth muscle myosin heavy chain 11
isoform SM2 [Homo sapiens]
Length = 1938
Score = 1769 bits (4583), Expect = 0.0
Identities = 916/1926 (47%), Positives = 1303/1926 (67%), Gaps = 13/1926 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
D ++L V + + P A WA ++L WVP + +GF SIK E DEV+VELV+ ++V
Sbjct: 10 DEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKV 69
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
T+ +DD+QK NPPKF K+EDM+ELT LNEASVLHNL++RY+S LIYTYSGLFCVV+NPYK
Sbjct: 70 TVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYK 129
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
LPIYSE +++ +KGKKRHEMPPHI+AIADTAYRSMLQ+REDQSILCTGESGAGKTENTK
Sbjct: 130 HLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTK 189
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVIQYLA VA + + K + GELE QLLQANPILEAFGN+KTVK
Sbjct: 190 KVIQYLAVVASSHKGKKDTSIT--------------GELEKQLLQANPILEAFGNAKTVK 235
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
NDNSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFY ++ G K
Sbjct: 236 NDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKM 295
Query: 907 KSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLL 1086
+S+ LLEG +NY FL N + +P D + F T+ +M IMGF+++E SI++VVS+VL
Sbjct: 296 RSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQ 355
Query: 1087 LGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQE 1266
LGN+ F +E+ +DQA + D+ QKVCHL+G+ V + ++ L PRIKVGR+ V KAQ +E
Sbjct: 356 LGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKE 415
Query: 1267 QAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQIC 1446
QA+FAVEA+AKA+YERLF+W++TR+NK+LD+THRQGASF+GILDIAGFEIF++NSFEQ+C
Sbjct: 416 QADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLC 475
Query: 1447 INYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEK---PMGVLALL 1617
INYTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP I+LIE+ P GVLALL
Sbjct: 476 INYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALL 535
Query: 1618 DEECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKN 1794
DEEC FPKA DKSFVEKL HPKF P ++ K+ F+++HYAG+VDY+A WL KN
Sbjct: 536 DEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKN 595
Query: 1795 MDPLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQ 1962
MDPLN+NV L+ S+D FVA +WKD + G+ A+M E++ +++KGMFRTV Q
Sbjct: 596 MDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQ 655
Query: 1963 LHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGF 2142
L+KEQL KLMTTLRNT+P+FVRCIIPNHEK+SGK+++ LVLEQLRCNGVLEGIRICRQGF
Sbjct: 656 LYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGF 715
Query: 2143 PNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVL 2322
PNR+ FQEFR RYEIL + IPK F+DGK++ MI AL++D NLYRIGQSK+FFRTGVL
Sbjct: 716 PNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVL 775
Query: 2323 AHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWW 2502
AHLEEERDLK+T +IM FQA CRG+L+R+ + N AYLKLRNWQWW
Sbjct: 776 AHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWW 835
Query: 2503 RLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQ 2682
RLFTKVKPLLQVTR ++E++AK+DEL+ TKER K E++ +E E+K Q+ E+ ++QEQ
Sbjct: 836 RLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQ 895
Query: 2683 LQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDX 2862
LQ E+E AE +++R RL + QELE I+++M RL R+K + + D
Sbjct: 896 LQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDL 955
Query: 2863 XXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQL 3042
+K + D + LTT L
Sbjct: 956 EEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNL 1015
Query: 3043 LDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKM 3222
+ EE+AK+ K K + E+ + ELE L +E + + ELE+ KRKL + D + +A+
Sbjct: 1016 AEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQ 1075
Query: 3223 GKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARN 3402
++ EL QL K++EELQ L R D+E A K++R+++ I +L+ED+++ER ARN
Sbjct: 1076 AQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARN 1135
Query: 3403 KAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIE 3582
KAE +R++ +LE +K ++ D +D Q+L +++++EV K+A+++ + E +++
Sbjct: 1136 KAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQ 1195
Query: 3583 EQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRK 3762
E + K ++ VEEL +Q+EQ K+ ++ L+K + ++E AD+A E+ +L ++ +++ K+K
Sbjct: 1196 EMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKK 1255
Query: 3763 IHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXX 3942
EA + E+Q+ ++ + + L D++ + ++E++ + + E E + + +A+
Sbjct: 1256 KLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS 1315
Query: 3943 XXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGE 4122
TR K+ + RQLE+E+N+L D+ +E + +LE+ I +
Sbjct: 1316 QLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSD 1375
Query: 4123 ARRKAEE--SVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSME 4296
+++K ++ S + LEE +K+ +++E+L +Q EE A +++ ++K ++QQEL+D ++
Sbjct: 1376 SKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1435
Query: 4297 LENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIM 4476
L+N R + EK+Q+KF+ +AEE+ K +RD E R++ET+ LSL ++
Sbjct: 1436 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 1495
Query: 4477 KEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNL 4656
E EE +R + L+ E++D +S+KDD GKNVHELEK+KR+LE ++ +M+ Q+EELED L
Sbjct: 1496 LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDEL 1555
Query: 4657 QIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGA 4836
Q EDA+LRLEV QALK + +R + +D + EEKRR L +Q+ + E ELE+E++ ++ A
Sbjct: 1556 QATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALA 1615
Query: 4837 VSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALL 5016
+ +KK+E + +LE Q + A + +EE ++Q E E+AR ++++I A
Sbjct: 1616 AAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATA 1675
Query: 5017 READRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRA---KGGGISSEEKRRLE 5187
+E ++K +++EA+ QL+E +ARKQ A G +EKRRLE
Sbjct: 1676 KENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE 1735
Query: 5188 AKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNR 5367
A+IAQ Q N E D+ RKA Q EQ++ +L+ ER+ QK E+ +Q LER N+
Sbjct: 1736 ARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNK 1795
Query: 5368 DYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTT 5547
+ ++K+ E+E +S+ ++ +AALEAK+ LE+Q+ E +EK AA ++ ++ +K+L +
Sbjct: 1796 ELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEIL 1855
Query: 5548 QQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANE 5727
Q EDE++ EQ KE EK N + + L+RQL+EAE+E R R +QRE D+ ++NE
Sbjct: 1856 LQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNE 1915
Query: 5728 QLTREL 5745
+ RE+
Sbjct: 1916 AMGREV 1921
Score = 93.2 bits (230), Expect = 7e-17
Identities = 110/537 (20%), Positives = 206/537 (37%), Gaps = 25/537 (4%)
Frame = +1
Query: 4216 EESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKAL 4395
EE AKE LQ K+ QQ+ E+ ELE QK SQ+ EE+ +Q+ L
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELE------------QK--HSQLTEEKNLLQEQL 896
Query: 4396 LDRDAMSQELRDRETRVLSLLNEVDI----MKEHLEESDRVRRSLQQELQDSISNKDDFG 4563
+ E + R+ + E++ M+ LEE + + LQ E + D
Sbjct: 897 QAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLE 956
Query: 4564 KNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
+ + E E A++ L+ E ++++LED + + +D +L + L+ +N
Sbjct: 957 EQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNL- 1015
Query: 4744 VEAEEKRRGLLK-------QIRDLENELENEKRGKSGAVSHRKKIEN------------- 4863
E EEK + L K I +LE L+ E++ + ++K+E
Sbjct: 1016 AEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQ 1075
Query: 4864 -QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFR 5040
QI EL+ QL + +EE + ++ R+ + I+ L + D +
Sbjct: 1076 AQIAELKMQLA---KKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERA 1132
Query: 5041 AVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXX 5220
A +Q R+ E L + + + KR E + +
Sbjct: 1133 ARNKAEKQKRDLGEELEALKTELEDTLDSTATQQ------ELRAKREQEVTVLKKALDEE 1186
Query: 5221 XXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES 5400
++ +Q+ AQ +E++T L + + KQ+LE+ N D
Sbjct: 1187 TRSHEAQVQEMRQKHAQA-VEELTEQLEQFKRAKANLDKNKQTLEKENAD---------- 1235
Query: 5401 GAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANE 5580
L +L V GQ K ++LE ++ + + D +RA
Sbjct: 1236 -------------------LAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 1276
Query: 5581 QAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
+ + + K + ++ L+EAE + + ++ + D + ++ TR+ +N
Sbjct: 1277 ELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLN 1333
>gi|12667788|ref|NP_002464.1| myosin, heavy polypeptide 9, non-muscle
[Homo sapiens]
gi|6166599|sp|P35579|MYH9_HUMAN Myosin heavy chain, nonmuscle type A
(Cellular myosin heavy chain, type A) (Nonmuscle myosin
heavy chain-A) (NMMHC-A)
gi|47678583|emb|CAG30412.1| MYH9 [Homo sapiens]
Length = 1960
Score = 1769 bits (4583), Expect = 0.0
Identities = 914/1924 (47%), Positives = 1290/1924 (66%), Gaps = 13/1924 (0%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL V + + +P A WA +KL WVP GF S+K E +E +VELV+ ++V +
Sbjct: 8 KYLYVDKNFINNPLAQADWAAKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKV 67
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDM+ELT LNEASVLHNLK+RYYS LIYTYSGLFCVVINPYK L
Sbjct: 68 NKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNL 127
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYSE+++E +KGKKRHEMPPHI+AI DTAYRSM+Q+REDQSILCTGESGAGKTENTKKV
Sbjct: 128 PIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKV 187
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
IQYLA+VA + ++K GELE QLLQANPILEAFGN+KTVKND
Sbjct: 188 IQYLAYVASSHKSKKDQ-----------------GELERQLLQANPILEAFGNAKTVKND 230
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA++ER+FHIFY +L G K+
Sbjct: 231 NSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKT 290
Query: 913 EYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 1092
+ LLE + YRFL N +T+P D F T+ +MRIMG ++E ++RV+S VL LG
Sbjct: 291 DLLLEPYNKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLG 350
Query: 1093 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA 1272
N+ F +E+ +DQA + D+ QKV HLLG+ V + + L PRIKVGR++V KAQ +EQA
Sbjct: 351 NIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQA 410
Query: 1273 EFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICIN 1452
+FA+EA+AKA+YER+F+WLV RINK+LD+T RQGASFIGILDIAGFEIFD+NSFEQ+CIN
Sbjct: 411 DFAIEALAKATYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCIN 470
Query: 1453 YTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDE 1623
YTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP IDLIEKP G+LALLDE
Sbjct: 471 YTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDE 530
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMD 1800
EC FPKA DKSFVEK+ + HPKF P ++ K+ F ++HYAG+VDY AD+WLMKNMD
Sbjct: 531 ECWFPKATDKSFVEKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMD 590
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQLH 1968
PLN+N+ L+ S+D FV+ +WKD + G+ A M+ETA ++RKGMFRTV QL+
Sbjct: 591 PLNDNIATLLHQSSDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLY 650
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
KEQL KLM TLRNT+P+FVRCIIPNHEKK+GK++ +LVL+QLRCNGVLEGIRICRQGFPN
Sbjct: 651 KEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPN 710
Query: 2149 RVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAH 2328
RV FQEFR RYEILTP+ IPK F+DGK++ MI AL++D+NLYRIGQSKVFFR GVLAH
Sbjct: 711 RVVFQEFRQRYEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAH 770
Query: 2329 LEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRL 2508
LEEERDLK+T +I+ FQA CRG+L+R+ + N AYLKLRNWQWWRL
Sbjct: 771 LEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRL 830
Query: 2509 FTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQ 2688
FTKVKPLLQV+R ++E+ AK++EL +E+ L E+ E E Q++ E+ +QEQLQ
Sbjct: 831 FTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQ 890
Query: 2689 QESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXX 2868
E+E AE +++R RL + QELE I +D+ R+ ++K + +++
Sbjct: 891 AETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEE 950
Query: 2869 XXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLD 3048
+K + +D TT L +
Sbjct: 951 QLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTE 1010
Query: 3049 HEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGK 3228
EE++K K K + E + +LE+ L RE + + ELE+ +RKL + D D +AE +
Sbjct: 1011 EEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQ 1070
Query: 3229 VEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKA 3408
+ EL QL K++EELQ L R +EE+A + K++R++++ I EL+ED+E+ER +RNKA
Sbjct: 1071 IAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKA 1130
Query: 3409 EMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQ 3588
E +R++ +LE +K ++ D +D Q+L S++++EVN K+ +E+ T E +I+E
Sbjct: 1131 EKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEM 1190
Query: 3589 KAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIH 3768
+ K S+ VEEL +Q+EQ K+ ++ LEK + + ER ++A E+ +L + D + KRK
Sbjct: 1191 RQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKV 1250
Query: 3769 EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXX 3948
EA L E+Q E + + L D++ + + ELD++ + + + + + + +
Sbjct: 1251 EAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQL 1310
Query: 3949 XXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEAR 4128
R K++ + +Q+EDEKN+ ++ EE E + +LEK+I + +
Sbjct: 1311 QDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMK 1370
Query: 4129 RKAEESVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
+K E+SV + EE+++K +D+E L ++ EE A +++ ++K ++QQEL+D ++L+
Sbjct: 1371 KKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLD 1430
Query: 4303 NVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKE 4482
+ R S + EK+QKKF+ +AEE+ K +RD E R++ET+ LSL ++ E
Sbjct: 1431 HQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAME 1490
Query: 4483 HLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQI 4662
E +R+ + + E++D +S+KDD GK+VHELEK+KR+LE ++ +M+ Q+EELED LQ
Sbjct: 1491 QKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQA 1550
Query: 4663 AEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVS 4842
EDA+LRLEV QA+K++ +R + +D ++EEK++ L++Q+R++E ELE+E++ +S AV+
Sbjct: 1551 TEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVA 1610
Query: 4843 HRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLRE 5022
RKK+E + +LE ++ AN+ ++E + E ++ R ++E+I A +E
Sbjct: 1611 ARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKE 1670
Query: 5023 ADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKG---GGISSEEKRRLEAK 5193
++K +++EAE QL+E +A++Q A G ++ EEKRRLEA+
Sbjct: 1671 NEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEAR 1730
Query: 5194 IAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDY 5373
IAQ Q N EL D+ +KA +Q++QI TDL++ER+ QK E +Q LER N++
Sbjct: 1731 IAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKEL 1790
Query: 5374 KAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQ 5553
K K+ E+E +S+ +A + ALEAK+ LE+QL+ E +E+ AA + RR EK+L D Q
Sbjct: 1791 KVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQ 1850
Query: 5554 FEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQL 5733
+DE+R EQ K+ +K++ + + L+RQL+EAE+E R R +QRE +D + + +
Sbjct: 1851 VDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAM 1910
Query: 5734 TREL 5745
RE+
Sbjct: 1911 NREV 1914
Score = 57.4 bits (137), Expect = 4e-06
Identities = 68/433 (15%), Positives = 166/433 (37%), Gaps = 48/433 (11%)
Frame = +1
Query: 2533 QVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAE 2712
++ R + + R + ++L ++K+ + K H+ ++++ L+Q + E E+L+ E + + +
Sbjct: 1494 ELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATED 1553
Query: 2713 LD----------------DIRGRLQTRNQELEYIVNDMRD---RLSXXXXXXXXXXXXRR 2835
D++GR + ++ + +V +R+ L R+
Sbjct: 1554 AKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARK 1613
Query: 2836 KQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXX 3015
K ++D + + + +
Sbjct: 1614 KLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEK 1673
Query: 3016 XXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELED 3195
+ +++ +E +AK + + + EL ++ + + KR+L A +
Sbjct: 1674 KLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQ 1733
Query: 3196 SKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELR-- 3369
++ L E+ G E +N++L K + ++ T + E ++ + + ++ EL+
Sbjct: 1734 LEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVK 1793
Query: 3370 -EDMETERNARNKAEMTRREV-VAQLE---------------------KVKGDVLDKVDE 3480
++ME ++ KA +T E +AQLE K DVL +VD+
Sbjct: 1794 LQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDD 1853
Query: 3481 ----ATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKK 3648
A +D + + KR +E+ + + + + K R++E+ + + +
Sbjct: 1854 ERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQ-RANASRRKLQRELEDATETADAMNR 1912
Query: 3649 QRSQLEKQQNQAD 3687
+ S L+ + + D
Sbjct: 1913 EVSSLKNKLRRGD 1925
>gi|13124879|ref|NP_002465.1| smooth muscle myosin heavy chain 11
isoform SM1 [Homo sapiens]
gi|13432177|sp|P35749|MYHB_HUMAN Myosin heavy chain, smooth muscle
isoform (SMMHC)
Length = 1972
Score = 1769 bits (4583), Expect = 0.0
Identities = 916/1926 (47%), Positives = 1303/1926 (67%), Gaps = 13/1926 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
D ++L V + + P A WA ++L WVP + +GF SIK E DEV+VELV+ ++V
Sbjct: 10 DEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKV 69
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
T+ +DD+QK NPPKF K+EDM+ELT LNEASVLHNL++RY+S LIYTYSGLFCVV+NPYK
Sbjct: 70 TVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYK 129
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
LPIYSE +++ +KGKKRHEMPPHI+AIADTAYRSMLQ+REDQSILCTGESGAGKTENTK
Sbjct: 130 HLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTK 189
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVIQYLA VA + + K + GELE QLLQANPILEAFGN+KTVK
Sbjct: 190 KVIQYLAVVASSHKGKKDTSIT--------------GELEKQLLQANPILEAFGNAKTVK 235
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
NDNSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFY ++ G K
Sbjct: 236 NDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKM 295
Query: 907 KSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLL 1086
+S+ LLEG +NY FL N + +P D + F T+ +M IMGF+++E SI++VVS+VL
Sbjct: 296 RSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQ 355
Query: 1087 LGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQE 1266
LGN+ F +E+ +DQA + D+ QKVCHL+G+ V + ++ L PRIKVGR+ V KAQ +E
Sbjct: 356 LGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKE 415
Query: 1267 QAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQIC 1446
QA+FAVEA+AKA+YERLF+W++TR+NK+LD+THRQGASF+GILDIAGFEIF++NSFEQ+C
Sbjct: 416 QADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLC 475
Query: 1447 INYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEK---PMGVLALL 1617
INYTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP I+LIE+ P GVLALL
Sbjct: 476 INYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALL 535
Query: 1618 DEECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKN 1794
DEEC FPKA DKSFVEKL HPKF P ++ K+ F+++HYAG+VDY+A WL KN
Sbjct: 536 DEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKN 595
Query: 1795 MDPLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQ 1962
MDPLN+NV L+ S+D FVA +WKD + G+ A+M E++ +++KGMFRTV Q
Sbjct: 596 MDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQ 655
Query: 1963 LHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGF 2142
L+KEQL KLMTTLRNT+P+FVRCIIPNHEK+SGK+++ LVLEQLRCNGVLEGIRICRQGF
Sbjct: 656 LYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGF 715
Query: 2143 PNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVL 2322
PNR+ FQEFR RYEIL + IPK F+DGK++ MI AL++D NLYRIGQSK+FFRTGVL
Sbjct: 716 PNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVL 775
Query: 2323 AHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWW 2502
AHLEEERDLK+T +IM FQA CRG+L+R+ + N AYLKLRNWQWW
Sbjct: 776 AHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWW 835
Query: 2503 RLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQ 2682
RLFTKVKPLLQVTR ++E++AK+DEL+ TKER K E++ +E E+K Q+ E+ ++QEQ
Sbjct: 836 RLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQ 895
Query: 2683 LQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDX 2862
LQ E+E AE +++R RL + QELE I+++M RL R+K + + D
Sbjct: 896 LQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDL 955
Query: 2863 XXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQL 3042
+K + D + LTT L
Sbjct: 956 EEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNL 1015
Query: 3043 LDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKM 3222
+ EE+AK+ K K + E+ + ELE L +E + + ELE+ KRKL + D + +A+
Sbjct: 1016 AEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQ 1075
Query: 3223 GKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARN 3402
++ EL QL K++EELQ L R D+E A K++R+++ I +L+ED+++ER ARN
Sbjct: 1076 AQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARN 1135
Query: 3403 KAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIE 3582
KAE +R++ +LE +K ++ D +D Q+L +++++EV K+A+++ + E +++
Sbjct: 1136 KAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQ 1195
Query: 3583 EQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRK 3762
E + K ++ VEEL +Q+EQ K+ ++ L+K + ++E AD+A E+ +L ++ +++ K+K
Sbjct: 1196 EMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKK 1255
Query: 3763 IHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXX 3942
EA + E+Q+ ++ + + L D++ + ++E++ + + E E + + +A+
Sbjct: 1256 KLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS 1315
Query: 3943 XXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGE 4122
TR K+ + RQLE+E+N+L D+ +E + +LE+ I +
Sbjct: 1316 QLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSD 1375
Query: 4123 ARRKAEE--SVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSME 4296
+++K ++ S + LEE +K+ +++E+L +Q EE A +++ ++K ++QQEL+D ++
Sbjct: 1376 SKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1435
Query: 4297 LENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIM 4476
L+N R + EK+Q+KF+ +AEE+ K +RD E R++ET+ LSL ++
Sbjct: 1436 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 1495
Query: 4477 KEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNL 4656
E EE +R + L+ E++D +S+KDD GKNVHELEK+KR+LE ++ +M+ Q+EELED L
Sbjct: 1496 LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDEL 1555
Query: 4657 QIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGA 4836
Q EDA+LRLEV QALK + +R + +D + EEKRR L +Q+ + E ELE+E++ ++ A
Sbjct: 1556 QATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALA 1615
Query: 4837 VSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALL 5016
+ +KK+E + +LE Q + A + +EE ++Q E E+AR ++++I A
Sbjct: 1616 AAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATA 1675
Query: 5017 READRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRA---KGGGISSEEKRRLE 5187
+E ++K +++EA+ QL+E +ARKQ A G +EKRRLE
Sbjct: 1676 KENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE 1735
Query: 5188 AKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNR 5367
A+IAQ Q N E D+ RKA Q EQ++ +L+ ER+ QK E+ +Q LER N+
Sbjct: 1736 ARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNK 1795
Query: 5368 DYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTT 5547
+ ++K+ E+E +S+ ++ +AALEAK+ LE+Q+ E +EK AA ++ ++ +K+L +
Sbjct: 1796 ELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEIL 1855
Query: 5548 QQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANE 5727
Q EDE++ EQ KE EK N + + L+RQL+EAE+E R R +QRE D+ ++NE
Sbjct: 1856 LQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNE 1915
Query: 5728 QLTREL 5745
+ RE+
Sbjct: 1916 AMGREV 1921
Score = 93.2 bits (230), Expect = 7e-17
Identities = 110/537 (20%), Positives = 206/537 (37%), Gaps = 25/537 (4%)
Frame = +1
Query: 4216 EESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKAL 4395
EE AKE LQ K+ QQ+ E+ ELE QK SQ+ EE+ +Q+ L
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELE------------QK--HSQLTEEKNLLQEQL 896
Query: 4396 LDRDAMSQELRDRETRVLSLLNEVDI----MKEHLEESDRVRRSLQQELQDSISNKDDFG 4563
+ E + R+ + E++ M+ LEE + + LQ E + D
Sbjct: 897 QAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLE 956
Query: 4564 KNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
+ + E E A++ L+ E ++++LED + + +D +L + L+ +N
Sbjct: 957 EQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNL- 1015
Query: 4744 VEAEEKRRGLLK-------QIRDLENELENEKRGKSGAVSHRKKIEN------------- 4863
E EEK + L K I +LE L+ E++ + ++K+E
Sbjct: 1016 AEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQ 1075
Query: 4864 -QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFR 5040
QI EL+ QL + +EE + ++ R+ + I+ L + D +
Sbjct: 1076 AQIAELKMQLA---KKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERA 1132
Query: 5041 AVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXX 5220
A +Q R+ E L + + + KR E + +
Sbjct: 1133 ARNKAEKQKRDLGEELEALKTELEDTLDSTATQQ------ELRAKREQEVTVLKKALDEE 1186
Query: 5221 XXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES 5400
++ +Q+ AQ +E++T L + + KQ+LE+ N D
Sbjct: 1187 TRSHEAQVQEMRQKHAQA-VEELTEQLEQFKRAKANLDKNKQTLEKENAD---------- 1235
Query: 5401 GAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANE 5580
L +L V GQ K ++LE ++ + + D +RA
Sbjct: 1236 -------------------LAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 1276
Query: 5581 QAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
+ + + K + ++ L+EAE + + ++ + D + ++ TR+ +N
Sbjct: 1277 ELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLN 1333
>gi|1346644|sp|P35748|MYHB_RABIT Myosin heavy chain, smooth muscle
isoform (SMMHC)
gi|165490|gb|AAA31395.1| myosin heavy chain
Length = 1972
Score = 1759 bits (4557), Expect = 0.0
Identities = 911/1926 (47%), Positives = 1300/1926 (67%), Gaps = 13/1926 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
D ++L V + + P A W ++L WVP + +GF SIK E DEV+VELV+ ++V
Sbjct: 10 DEKFLFVDKNFINSPVAQADWVAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKV 69
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
T+ +DD+QK NPPKF K+EDM+ELT LNEASVLHNL++RY+S LIYTYSGLFCVV+NPYK
Sbjct: 70 TVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYK 129
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
+LPIYSE +++ +KGKKRHEMPPHI+AIADTAYRSMLQ+REDQSILCTGESGAGKTENTK
Sbjct: 130 QLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTK 189
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVIQYLA VA + + K + GELE QLLQANPILEAFGN+KTVK
Sbjct: 190 KVIQYLAVVASSHKGKKDTSIT--------------GELEKQLLQANPILEAFGNAKTVK 235
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
NDNSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA++ER+FHIFY ++ G K
Sbjct: 236 NDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQAREERTFHIFYYLIAGAKEKM 295
Query: 907 KSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLL 1086
+++ LLEG +NY FL N + +P D + F T+ +M IMGF+++E S+++VVS+VL
Sbjct: 296 RNDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMSIMGFSEEEQLSVLKVVSSVLQ 355
Query: 1087 LGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQE 1266
LGN+ F +E+ +DQA + D+ QKVCHL+G+ V + ++ L PRIKVGR+ V KAQ +E
Sbjct: 356 LGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKE 415
Query: 1267 QAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQIC 1446
QA+FAVEA+AKA+YERLF+W+++R+NK+LD+THRQGASF+GILDIAGFEIF++NSFEQ+C
Sbjct: 416 QADFAVEALAKATYERLFRWILSRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLC 475
Query: 1447 INYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEK---PMGVLALL 1617
INYTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP I+LIE+ P GVLALL
Sbjct: 476 INYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALL 535
Query: 1618 DEECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKN 1794
DEEC FPKA DKSFVEKL HPKF P ++ K+ F+++HYAG+VDY+A WL KN
Sbjct: 536 DEECWFPKATDKSFVEKLCTEQGNHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKN 595
Query: 1795 MDPLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQ 1962
MDPLN+NV L+ S+D FVA +WKD + G+ A+M E++ +++KGMFRTV Q
Sbjct: 596 MDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQ 655
Query: 1963 LHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGF 2142
L+KEQL KLMTTLRNT+P+FVRCIIPNHEK+SGK+++ LVLEQLRCNGVLEGIRICRQGF
Sbjct: 656 LYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGF 715
Query: 2143 PNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVL 2322
PNR+ FQEFR RYEIL + IPK F+DGK++ MI AL++D NLYRIGQSK+FFRTGVL
Sbjct: 716 PNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVL 775
Query: 2323 AHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWW 2502
AHLEEERDLK+T +IM FQA CRG+L+R+ + N AYLKLRNWQWW
Sbjct: 776 AHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWW 835
Query: 2503 RLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQ 2682
RLFTKVKPLLQVTR ++E++AK+DEL+ KER K E + +E ++K Q+ E+ ++QEQ
Sbjct: 836 RLFTKVKPLLQVTRQEEEMQAKEDELQKIKERQQKAESELQELQQKHTQLSEEKNLLQEQ 895
Query: 2683 LQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDX 2862
LQ E+E AE +++R RL + QELE I+++M RL R+K + + D
Sbjct: 896 LQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDL 955
Query: 2863 XXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQL 3042
+K + D + LTT L
Sbjct: 956 EEQLEEEEAARQKLQLEKVTAEAKIKKLEDDILVMDDQNNKLSKERKLLEERISDLTTNL 1015
Query: 3043 LDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKM 3222
+ EE+AK+ K K + E+ + ELE L +E + + ELE+ KRK+ E D + +A+
Sbjct: 1016 AEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKMDGEASDLHEQIADLQ 1075
Query: 3223 GKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARN 3402
++ EL QL K++EELQ L R ++E++ K++R+++ I +L+ED+++ER ARN
Sbjct: 1076 AQIAELKMQLAKKEEELQAALARLEDETSQKNNALKKIRELEGHISDLQEDLDSERAARN 1135
Query: 3403 KAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIE 3582
KAE +R++ +LE +K ++ D +D Q+L +++++EV K+A+++ + E +++
Sbjct: 1136 KAEKQKRDLGEELEALKTELEDTLDTTATQQELRAKREQEVTVLKKALDEETRSHEAQVQ 1195
Query: 3583 EQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRK 3762
E + K ++ VEEL +Q+EQ K+ ++ L+K + ++E AD+A E+ +L ++ +++ K+K
Sbjct: 1196 EMRQKHTQVVEELTEQLEQFKRAKANLDKTKQTLEKENADLAGELRVLGQAKQEVEHKKK 1255
Query: 3763 IHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXX 3942
E L E+Q+ ++ + + L D++ + ++E++ + + E E + + +A+
Sbjct: 1256 KLEVQLQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLSEAEGKAIKLAKEVASLGS 1315
Query: 3943 XXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGE 4122
TR K+ + RQLEDE+N+L ++ +E + +LE+ I +
Sbjct: 1316 QLQDTQELLQEETRQKLNVSTKLRQLEDERNSLQEQLDEEMEAKQNLERHISTLNIQLSD 1375
Query: 4123 ARRKAEE--SVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSME 4296
+++K ++ S + LEE +K+ +++E L +Q EE A +++ ++K ++QQEL+D ++
Sbjct: 1376 SKKKLQDFASTVESLEEGKKRFQKEIESLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1435
Query: 4297 LENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIM 4476
L+N R + EK+QKKF+ +AEE+ K +RD E R++ET+ LSL ++
Sbjct: 1436 LDNQRQLVSNLEKKQKKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 1495
Query: 4477 KEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNL 4656
E EE +R + L+ E++D +S+KDD GKNVHELEK+KR+LE ++ +M+ Q+EELED L
Sbjct: 1496 LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDEL 1555
Query: 4657 QIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGA 4836
Q EDA+LRLEV QALK + +R + +D + EEKRR L +Q+ + E ELE+E++ ++ A
Sbjct: 1556 QATEDAKLRLEVNMQALKVQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALA 1615
Query: 4837 VSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALL 5016
+ +KK+E + +LE Q + A + +EE ++Q E E+AR ++++I A
Sbjct: 1616 AAAKKKLEGDLKDLELQADSAIKGREEAIKQLLKLQAQMKDFQRELEDARASRDEIFATA 1675
Query: 5017 READRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRA---KGGGISSEEKRRLE 5187
+E ++K +++EA+ QL+E +ARKQ A G +EKRRLE
Sbjct: 1676 KENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE 1735
Query: 5188 AKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNR 5367
A+IAQ Q N E D+ RKA Q EQ++ +L+ ER+ QK E+ +Q LER N+
Sbjct: 1736 ARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNK 1795
Query: 5368 DYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTT 5547
+ K+K+ E+E +S+ ++ +AALEAK+ LE+Q+ E +EK AA +A ++ +K+L +
Sbjct: 1796 ELKSKLQEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAAAKALKQRDKKLKEML 1855
Query: 5548 QQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANE 5727
Q EDE++ EQ KE EK N K + L+RQL+EAE+E R R +QRE D+ ++NE
Sbjct: 1856 LQVEDERKMAEQYKEQAEKGNAKVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNE 1915
Query: 5728 QLTREL 5745
+ RE+
Sbjct: 1916 AMGREV 1921
Score = 91.7 bits (226), Expect = 2e-16
Identities = 103/530 (19%), Positives = 208/530 (38%), Gaps = 18/530 (3%)
Frame = +1
Query: 4216 EESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKAL 4395
EE AKE LQ K+ QQ+ E EL+ ++ H + + + Q+ E +A
Sbjct: 851 EEEMQAKEDELQKIKERQQKAES---ELQELQQKHTQLSEEKNLLQEQLQAETELYAEA- 906
Query: 4396 LDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVH 4575
+ M L ++ + +L+E M+ LEE + + LQ E + D + +
Sbjct: 907 ---EEMRVRLAAKKQELEEILHE---MEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 960
Query: 4576 ELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAE 4755
E E A++ L+ E ++++LED++ + +D +L + L+ +N E E
Sbjct: 961 EEEAARQKLQLEKVTAEAKIKKLEDDILVMDDQNNKLSKERKLLEERISDLTTNL-AEEE 1019
Query: 4756 EKRRGLLK-------QIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL-----EVA 4899
EK + L K I +LE L+ E++ + ++K++ + +L +Q+ ++A
Sbjct: 1020 EKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKMDGEASDLHEQIADLQAQIA 1079
Query: 4900 N------RLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAERE 5061
+ +EE + ++ R+ + I+ L + D + A +
Sbjct: 1080 ELKMQLAKKEEELQAALARLEDETSQKNNALKKIRELEGHISDLQEDLDSERAARNKAEK 1139
Query: 5062 QLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCE 5241
Q R+ E L + + + KR E + + +
Sbjct: 1140 QKRDLGEELEALKTELEDTLDTTATQQ------ELRAKREQEVTVLKKALDEETRSHEAQ 1193
Query: 5242 LAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRAR 5421
+ +Q+ QV +E++T L + + KQ+LE+ N D
Sbjct: 1194 VQEMRQKHTQV-VEELTEQLEQFKRAKANLDKTKQTLEKENAD----------------- 1235
Query: 5422 AQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLE 5601
L +L V GQ K ++LE +L + + D +RA + + +
Sbjct: 1236 ------------LAGELRVLGQAKQEVEHKKKKLEVQLQELQSKCSDGERARAELNDKVH 1283
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
K + ++ L EAE + + + ++ + D + ++ TR+ +N
Sbjct: 1284 KLQNEVESVTGMLSEAEGKAIKLAKEVASLGSQLQDTQELLQEETRQKLN 1333
>gi|50510675|dbj|BAD32323.1| mKIAA0866 protein [Mus musculus]
Length = 1984
Score = 1758 bits (4554), Expect = 0.0
Identities = 911/1926 (47%), Positives = 1298/1926 (67%), Gaps = 13/1926 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
D ++L V + + P A W +KL WVP + +GF SIK E DEV+VELV+ ++V
Sbjct: 22 DEKFLFVDKNFMNSPMAQADWVAKKLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKV 81
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
T+ +DD+QK NPPKF K+EDM+ELT LNEASVLHNL++RY+S LIYTYSGLFCVV+NPYK
Sbjct: 82 TVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYK 141
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
LPIYSE +++ +KGKKRHEMPPHI+AIADTAYRSMLQ+REDQSILCTGESGAGKTENTK
Sbjct: 142 YLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTK 201
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVIQYLA VA + + K ++ GELE QLLQANPILEAFGN+KTVK
Sbjct: 202 KVIQYLAVVASSHKGKKDSSIT--------------GELEKQLLQANPILEAFGNAKTVK 247
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
NDNSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFY +L G K
Sbjct: 248 NDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYLLAGAKEKM 307
Query: 907 KSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLL 1086
KS+ LLE ++Y FL N + +P D + F T+ +M IMGF ++E +I++VVS+VL
Sbjct: 308 KSDLLLESFNSYTFLSNGFVPIPAAQDDEMFQETLEAMSIMGFNEEEQLAILKVVSSVLQ 367
Query: 1087 LGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQE 1266
LGN+ F +E+ +DQA + D+ QKVCHL+G+ V + +A L PRIKVGR+ V KAQ +E
Sbjct: 368 LGNIVFKKERNTDQASMPDNTAAQKVCHLVGINVTDFTRAILTPRIKVGRDVVQKAQTKE 427
Query: 1267 QAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQIC 1446
QA+FA+EA+AKA+YERLF+W+++R+NK+LD+THRQGASF+GILDIAGFEIF++NSFEQ+C
Sbjct: 428 QADFAIEALAKATYERLFRWILSRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLC 487
Query: 1447 INYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEK---PMGVLALL 1617
INYTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP I+LIE+ P GVLALL
Sbjct: 488 INYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALL 547
Query: 1618 DEECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKN 1794
DEEC FPKA DKSFVEKL HPKF P ++ K+ F+++HYAG+VDY+A WL KN
Sbjct: 548 DEECWFPKATDKSFVEKLCSEQGNHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKN 607
Query: 1795 MDPLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQ 1962
MDPLN+NV L+ S+D FVA +WKD + G+ A+M E++ +++KGMFRTV Q
Sbjct: 608 MDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQ 667
Query: 1963 LHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGF 2142
L+KEQL KLMTTLRNT+P+FVRCIIPNHEK+SGK+++ LVLEQLRCNGVLEGIRICRQGF
Sbjct: 668 LYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGF 727
Query: 2143 PNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVL 2322
PNR+ FQEFR RYEIL + IPK F+DGK++ MI AL++D NLYRIGQSK+FFRTGVL
Sbjct: 728 PNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVL 787
Query: 2323 AHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWW 2502
AHLEEERDLK+T +IM FQA CRG+L+R+ +T N AYLKLRNWQWW
Sbjct: 788 AHLEEERDLKITDVIMAFQAMCRGYLARKAFTKRQQQLTAMKVIQRNCAAYLKLRNWQWW 847
Query: 2503 RLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQ 2682
RLFTKVKPLLQVTR ++E++AK++E++ KER K E + +E E+K Q+ E+ ++QEQ
Sbjct: 848 RLFTKVKPLLQVTRQEEEMQAKEEEMQKIKERQQKAETELKELEQKHTQLAEEKTLLQEQ 907
Query: 2683 LQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDX 2862
LQ E+E AE +++R RL + QELE I+++M RL R+K + + D
Sbjct: 908 LQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDL 967
Query: 2863 XXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQL 3042
+K + D LTT L
Sbjct: 968 EEQLEEEEAARQKLQLEKVTAEAKIKKLEDDILVMDDQNSKLSKERKLLEERVSDLTTNL 1027
Query: 3043 LDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKM 3222
+ EE+AK+ K K + E+ + ELE L +E + + ELE+ KRKL + D + +A+
Sbjct: 1028 AEEEEKAKNLTKLKSKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQ 1087
Query: 3223 GKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARN 3402
++ EL QL K++EELQ L R DEE A K++R+++ I +L+ED+++ER ARN
Sbjct: 1088 AQIAELKMQLAKKEEELQAALARLDEEIAQKNNALKKIRELEGHISDLQEDLDSERAARN 1147
Query: 3403 KAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIE 3582
KAE +R++ +LE +K ++ D +D Q+L +++++EV K+A+++ + E +++
Sbjct: 1148 KAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQ 1207
Query: 3583 EQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRK 3762
E + K ++ VEEL +Q+EQ K+ ++ L+K + ++E AD+A E+ +L ++ +++ K+K
Sbjct: 1208 EMRQKHTQAVEELTEQLEQFKRAKANLDKSKQTLEKENADLAGELRVLGQAKQEVEHKKK 1267
Query: 3763 IHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXX 3942
E L ++Q+ ++ + + L D++ + ++E++ + + E E + + +A+
Sbjct: 1268 KLEVQLQDLQSKCSDGERARAELSDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLGS 1327
Query: 3943 XXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGE 4122
TR K+ + RQLEDE+N+L D+ +E + +LE+ + +
Sbjct: 1328 QLQDTQELLQEETRQKLNVSTKLRQLEDERNSLQDQLDEEMEAKQNLERHVSTLNIQLSD 1387
Query: 4123 ARRKAEE--SVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSME 4296
+++K ++ S + +EE +K+ +++E L +Q EE A +++ ++K ++QQEL+D ++
Sbjct: 1388 SKKKLQDFASTIEVMEEGKKRLQKEMEGLSQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1447
Query: 4297 LENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIM 4476
L+N R + EK+QKKF+ +AEE+ K +RD E R++ET+ LSL ++
Sbjct: 1448 LDNQRQLVSNLEKKQKKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 1507
Query: 4477 KEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNL 4656
E EE +R + L+ E++D +S+KDD GKNVHELEK+KR+LE ++ +M+ Q+EELED L
Sbjct: 1508 LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDEL 1567
Query: 4657 QIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGA 4836
Q EDA+LRLEV QALK + +R + +D + EEKRR L +Q+ + E ELE+E++ ++ A
Sbjct: 1568 QATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALA 1627
Query: 4837 VSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALL 5016
+ +KK+E + +LE Q + A + +EE ++Q E ++AR ++++I A
Sbjct: 1628 AAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELDDARASRDEIFATS 1687
Query: 5017 READRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRA---KGGGISSEEKRRLE 5187
+E ++K +++EA+ QL+E +ARKQ A G +EKRRLE
Sbjct: 1688 KENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNTLQDEKRRLE 1747
Query: 5188 AKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNR 5367
A+IAQ Q N E D+ RKA +Q EQ++ +L+ ER+ QK E+ +Q LER N+
Sbjct: 1748 ARIAQLEEELEEEQGNMEAMSDRVRKATLQAEQLSNELATERSTAQKNESARQQLERQNK 1807
Query: 5368 DYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTT 5547
+ ++K+ E+E +++ ++ +AALEAK+ LE+Q+ E +EK AA ++ ++ +K+L +
Sbjct: 1808 ELRSKLQEVEGAVKAKLKSTVAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEVL 1867
Query: 5548 QQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANE 5727
Q EDE++ EQ KE EK N K + L+RQL+EAE+E R R +QRE D+ ++NE
Sbjct: 1868 LQVEDERKMAEQYKEQAEKGNTKVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNE 1927
Query: 5728 QLTREL 5745
+ RE+
Sbjct: 1928 AMGREV 1933
Score = 161 bits (407), Expect = 2e-37
Identities = 197/925 (21%), Positives = 387/925 (41%), Gaps = 68/925 (7%)
Frame = +1
Query: 2512 TKVKPLLQVTRTDDEIRAKDDEL-RATKERLL-KMEHDFRENEKKLDQVIVERAVIQEQL 2685
TK+K + ++ E+R K +E R E+L K+E D + +++ + + A ++ QL
Sbjct: 1038 TKLKSKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQL 1097
Query: 2686 -QQESENSAELDDIRGRLQTRN------QELEYIVNDMRDRLSXXXXXXXXXXXXRRKQM 2844
++E E A L + + +N +ELE ++D+++ L +R
Sbjct: 1098 AKKEEELQAALARLDEEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLG 1157
Query: 2845 ETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXX 3024
E + + +Q +++
Sbjct: 1158 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHTQAV 1217
Query: 3025 GLTTQLLDHEERAKHGV-KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSK 3201
T+ L+ +RAK + K+K LE + +L +L Q K E+E K+KL +L+D +
Sbjct: 1218 EELTEQLEQFKRAKANLDKSKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEVQLQDLQ 1277
Query: 3202 DHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDME 3381
++ EL++++ K E++ +E + K + + + + + +E ++
Sbjct: 1278 SKCSDGERARAELSDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLGSQLQDTQELLQ 1337
Query: 3382 TERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNA----TKRAIE 3549
E R K ++ + + QLE + + D++DE + + R +N +K+ ++
Sbjct: 1338 EE--TRQKLNVSTK--LRQLEDERNSLQDQLDEEMEAKQNLERHVSTLNIQLSDSKKKLQ 1393
Query: 3550 QIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQ 3729
T+E +EE K + +++E L Q E+ +LEK +N+ QE D+ ++ +
Sbjct: 1394 DFASTIE-VMEEGKKRLQKEMEGLSQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1452
Query: 3730 ASRADIDKKRKIHEAHLMEIQANLAE--SDEHKRTLIDQLERSRDELDHLNRVREEEEHA 3903
++++KK+K + L E + N++ +DE R + E+ L L R EE A
Sbjct: 1453 QLVSNLEKKQKKFDQLLAE-EKNISSKYADERDRAEAEAREKETKALS-LARALEEALEA 1510
Query: 3904 FANMQR--RLATAXXXXXXXXXXXXXXTRLKIANINRA------------RQLEDEKNAL 4041
++R ++ A ++ RA +LEDE A
Sbjct: 1511 KEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1570
Query: 4042 LDEKEEAE----GLRAHLEKEIHAARQGAGEARRKAEESVNQQLEEL------------- 4170
D K E L+ E+++ A + E RR+ + +++ EL
Sbjct: 1571 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1630
Query: 4171 RKKNLRDVEHLQKQLEESEVAKERILQSKKKIQ-------QELEDSSMELENVRASHRDS 4329
+KK D++ L+ Q + + +E ++ +K+Q +EL+D+ + + A+ +++
Sbjct: 1631 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELDDARASRDEIFATSKEN 1690
Query: 4330 EKRQKKFES---QMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESD 4500
EK+ K E+ Q+ E+ A ++A D +EL + LS N + K LE
Sbjct: 1691 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNTLQDEKRRLEA-- 1748
Query: 4501 RVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARL 4680
R+ + L++EL++ N + V KA E N++ + + N E AR
Sbjct: 1749 RIAQ-LEEELEEEQGNMEAMSDRV---RKATLQAEQLSNELATERSTAQKN----ESARQ 1800
Query: 4681 RLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIE 4860
+LE N+ L+S+ + + L +I LE ++E E R K A K+ +
Sbjct: 1801 QLERQNKELRSKLQEVEGAVKAKLKSTVAALEAKIAQLEEQVEQEAREKQAATKSLKQKD 1860
Query: 4861 NQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKF- 5037
++ E+ Q+E ++ E+Y + + + EEA + + I A R+ R+
Sbjct: 1861 KKLKEVLLQVEDERKMAEQYKEQAEKGNTKVKQLKRQLEEAEEESQRINANRRKLQRELD 1920
Query: 5038 ----------RAVEAEREQLREANE 5082
R V A + +LR NE
Sbjct: 1921 EATESNEAMGREVNALKSKLRRGNE 1945
Score = 95.9 bits (237), Expect = 1e-17
Identities = 119/601 (19%), Positives = 233/601 (37%), Gaps = 39/601 (6%)
Frame = +1
Query: 4066 GLRAHLEKE-------IHAARQGA--GEARRKAEESVNQQLEELR--KKNLRDVEHLQKQ 4212
G+ AHLE+E + A Q G RKA QQL ++ ++N L+
Sbjct: 785 GVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFTKRQQQLTAMKVIQRNCAAYLKLRNW 844
Query: 4213 LEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFE---SQMAEERVAV 4383
K + L + ++E++ E++ ++ + +E K+ E +Q+AEE+ +
Sbjct: 845 QWWRLFTKVKPLLQVTRQEEEMQAKEEEMQKIKERQQKAETELKELEQKHTQLAEEKTLL 904
Query: 4384 QKALLDRDAMSQELRDRETRVLSLLNEVDI----MKEHLEESDRVRRSLQQELQDSISNK 4551
Q+ L + E + R+ + E++ M+ LEE + + LQ E +
Sbjct: 905 QEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQM 964
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAI 4731
D + + E E A++ L+ E ++++LED++ + +D +L + L+
Sbjct: 965 LDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDDILVMDDQNSKLSKERKLLEERVSDLT 1024
Query: 4732 SNKDVEAEEKRRGLLK-------QIRDLENELENEKRGKSGAVSHRKKIEN--------- 4863
+N E EEK + L K I +LE L+ E++ + ++K+E
Sbjct: 1025 TNL-AEEEEKAKNLTKLKSKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQI 1083
Query: 4864 -----QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREAD 5028
QI EL+ QL + +EE + ++ R+ + I+ L + D
Sbjct: 1084 ADLQAQIAELKMQLA---KKEEELQAALARLDEEIAQKNNALKKIRELEGHISDLQEDLD 1140
Query: 5029 RKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXX 5208
+ A +Q R+ E L + + + KR E + +
Sbjct: 1141 SERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQ------ELRAKREQEVTVLKKA 1194
Query: 5209 XXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKIT 5388
++ +Q+ Q +E++T L + + KQ+LE+ N D
Sbjct: 1195 LDEETRSHEAQVQEMRQKHTQA-VEELTEQLEQFKRAKANLDKSKQTLEKENAD------ 1247
Query: 5389 ELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEK 5568
L +L V GQ K ++LE +L D + D +
Sbjct: 1248 -----------------------LAGELRVLGQAKQEVEHKKKKLEVQLQDLQSKCSDGE 1284
Query: 5569 RANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
RA + + + K + ++ L+EAE + + ++ + D + ++ TR+ +
Sbjct: 1285 RARAELSDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLGSQLQDTQELLQEETRQKL 1344
Query: 5749 N 5751
N
Sbjct: 1345 N 1345
>gi|109322|pir||A41604 myosin heavy chain, smooth muscle, long splice
form - rabbit
Length = 1972
Score = 1757 bits (4551), Expect = 0.0
Identities = 910/1926 (47%), Positives = 1299/1926 (67%), Gaps = 13/1926 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
D ++L V + + P A W ++L WVP + +GF SIK E DEV+VELV+ ++V
Sbjct: 10 DEKFLFVDKNFINSPVAQADWVAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKV 69
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
T+ +DD+QK NPPKF K+EDM+ELT LNEASVLHNL++RY+S LIYTYSGLFCVV+NPYK
Sbjct: 70 TVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYK 129
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
+LPIYSE +++ +KGKKRHEMPPHI+AIADTAYRSMLQ+REDQSILCTGESGAGKTENTK
Sbjct: 130 QLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTK 189
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVIQYLA VA + + K + GELE QLLQANPILEAFGN+KTVK
Sbjct: 190 KVIQYLAVVASSHKGKKDTSIT--------------GELEKQLLQANPILEAFGNAKTVK 235
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
NDNSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA++ER+FHIFY ++ G K
Sbjct: 236 NDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQAREERTFHIFYYLIAGAKEKM 295
Query: 907 KSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLL 1086
+++ LLEG +NY FL N + +P D + F + +M IMGF+++E S+++VVS+VL
Sbjct: 296 RNDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQEKVEAMSIMGFSEEEQLSVLKVVSSVLQ 355
Query: 1087 LGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQE 1266
LGN+ F +E+ +DQA + D+ QKVCHL+G+ V + ++ L PRIKVGR+ V KAQ +E
Sbjct: 356 LGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKE 415
Query: 1267 QAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQIC 1446
QA+FAVEA+AKA+YERLF+W+++R+NK+LD+THRQGASF+GILDIAGFEIF++NSFEQ+C
Sbjct: 416 QADFAVEALAKATYERLFRWILSRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLC 475
Query: 1447 INYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEK---PMGVLALL 1617
INYTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP I+LIE+ P GVLALL
Sbjct: 476 INYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALL 535
Query: 1618 DEECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKN 1794
DEEC FPKA DKSFVEKL HPKF P ++ K+ F+++HYAG+VDY+A WL KN
Sbjct: 536 DEECWFPKATDKSFVEKLCTEQGNHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKN 595
Query: 1795 MDPLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQ 1962
MDPLN+NV L+ S+D FVA +WKD + G+ A+M E++ +++KGMFRTV Q
Sbjct: 596 MDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQ 655
Query: 1963 LHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGF 2142
L+KEQL KLMTTLRNT+P+FVRCIIPNHEK+SGK+++ LVLEQLRCNGVLEGIRICRQGF
Sbjct: 656 LYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGF 715
Query: 2143 PNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVL 2322
PNR+ FQEFR RYEIL + IPK F+DGK++ MI AL++D NLYRIGQSK+FFRTGVL
Sbjct: 716 PNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVL 775
Query: 2323 AHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWW 2502
AHLEEERDLK+T +IM FQA CRG+L+R+ + N AYLKLRNWQWW
Sbjct: 776 AHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWW 835
Query: 2503 RLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQ 2682
RLFTKVKPLLQVTR ++E++AK+DEL+ KER K E + +E ++K Q+ E+ ++QEQ
Sbjct: 836 RLFTKVKPLLQVTRQEEEMQAKEDELQKIKERQQKAESELQELQQKHTQLSEEKNLLQEQ 895
Query: 2683 LQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDX 2862
LQ E+E AE +++R RL + QELE I+++M RL R+K + + D
Sbjct: 896 LQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDL 955
Query: 2863 XXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQL 3042
+K + D + LTT L
Sbjct: 956 EEQLEEEEAARQKLQLEKVTAEAKIKKLEDDILVMDDQNNKLSKERKLLEERISDLTTNL 1015
Query: 3043 LDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKM 3222
+ EE+AK+ K K + E+ + ELE L +E + + ELE+ KRK+ E D + +A+
Sbjct: 1016 AEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKMDGEASDLHEQIADLQ 1075
Query: 3223 GKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARN 3402
++ EL QL K++EELQ L R ++E++ K++R+++ I +L+ED+++ER ARN
Sbjct: 1076 AQIAELKMQLAKKEEELQAALARLEDETSQKNNALKKIRELEGHISDLQEDLDSERAARN 1135
Query: 3403 KAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIE 3582
KAE +R++ +LE +K ++ D +D Q+L +++++EV K+A+++ + E +++
Sbjct: 1136 KAEKQKRDLGEELEALKTELEDTLDTTATQQELRAKREQEVTVLKKALDEETRSHEAQVQ 1195
Query: 3583 EQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRK 3762
E + K ++ VEEL +Q+EQ K+ ++ L+K + ++E AD+A E+ +L ++ +++ K+K
Sbjct: 1196 EMRQKHTQVVEELTEQLEQFKRAKANLDKTKQTLEKENADLAGELRVLGQAKQEVEHKKK 1255
Query: 3763 IHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXX 3942
E L E+Q+ ++ + + L D++ + ++E++ + + E E + + +A+
Sbjct: 1256 KLEVQLQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLSEAEGKAIKLAKEVASLGS 1315
Query: 3943 XXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGE 4122
TR K+ + RQLEDE+N+L ++ +E + +LE+ I +
Sbjct: 1316 QLQDTQELLQEETRQKLNVSTKLRQLEDERNSLQEQLDEEMEAKQNLERHISTLNIQLSD 1375
Query: 4123 ARRKAEE--SVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSME 4296
+++K ++ S + LEE +K+ +++E L +Q EE A +++ ++K ++QQEL+D ++
Sbjct: 1376 SKKKLQDFASTVESLEEGKKRFQKEIESLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1435
Query: 4297 LENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIM 4476
L+N R + EK+QKKF+ +AEE+ K +RD E R++ET+ LSL ++
Sbjct: 1436 LDNQRQLVSNLEKKQKKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 1495
Query: 4477 KEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNL 4656
E EE +R + L+ E++D +S+KDD GKNVHELEK+KR+LE ++ +M+ Q+EELED L
Sbjct: 1496 LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDEL 1555
Query: 4657 QIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGA 4836
Q EDA+LRLEV QALK + +R + +D + EEKRR L +Q+ + E ELE+E++ ++ A
Sbjct: 1556 QATEDAKLRLEVNMQALKVQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALA 1615
Query: 4837 VSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALL 5016
+ +KK+E + +LE Q + A + +EE ++Q E E+AR ++++I A
Sbjct: 1616 AAAKKKLEGDLKDLELQADSAIKGREEAIKQLLKLQAQMKDFQRELEDARASRDEIFATA 1675
Query: 5017 READRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRA---KGGGISSEEKRRLE 5187
+E ++K +++EA+ QL+E +ARKQ A G +EKRRLE
Sbjct: 1676 KENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE 1735
Query: 5188 AKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNR 5367
A+IAQ Q N E D+ RKA Q EQ++ +L+ ER+ QK E+ +Q LER N+
Sbjct: 1736 ARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNK 1795
Query: 5368 DYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTT 5547
+ K+K+ E+E +S+ ++ +AALEAK+ LE+Q+ E +EK AA +A ++ +K+L +
Sbjct: 1796 ELKSKLQEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAAAKALKQRDKKLKEML 1855
Query: 5548 QQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANE 5727
Q EDE++ EQ KE EK N K + L+RQL+EAE+E R R +QRE D+ ++NE
Sbjct: 1856 LQVEDERKMAEQYKEQAEKGNAKVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNE 1915
Query: 5728 QLTREL 5745
+ RE+
Sbjct: 1916 AMGREV 1921
Score = 91.7 bits (226), Expect = 2e-16
Identities = 103/530 (19%), Positives = 208/530 (38%), Gaps = 18/530 (3%)
Frame = +1
Query: 4216 EESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKAL 4395
EE AKE LQ K+ QQ+ E EL+ ++ H + + + Q+ E +A
Sbjct: 851 EEEMQAKEDELQKIKERQQKAES---ELQELQQKHTQLSEEKNLLQEQLQAETELYAEA- 906
Query: 4396 LDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVH 4575
+ M L ++ + +L+E M+ LEE + + LQ E + D + +
Sbjct: 907 ---EEMRVRLAAKKQELEEILHE---MEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 960
Query: 4576 ELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAE 4755
E E A++ L+ E ++++LED++ + +D +L + L+ +N E E
Sbjct: 961 EEEAARQKLQLEKVTAEAKIKKLEDDILVMDDQNNKLSKERKLLEERISDLTTNL-AEEE 1019
Query: 4756 EKRRGLLK-------QIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL-----EVA 4899
EK + L K I +LE L+ E++ + ++K++ + +L +Q+ ++A
Sbjct: 1020 EKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKMDGEASDLHEQIADLQAQIA 1079
Query: 4900 N------RLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAERE 5061
+ +EE + ++ R+ + I+ L + D + A +
Sbjct: 1080 ELKMQLAKKEEELQAALARLEDETSQKNNALKKIRELEGHISDLQEDLDSERAARNKAEK 1139
Query: 5062 QLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCE 5241
Q R+ E L + + + KR E + + +
Sbjct: 1140 QKRDLGEELEALKTELEDTLDTTATQQ------ELRAKREQEVTVLKKALDEETRSHEAQ 1193
Query: 5242 LAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRAR 5421
+ +Q+ QV +E++T L + + KQ+LE+ N D
Sbjct: 1194 VQEMRQKHTQV-VEELTEQLEQFKRAKANLDKTKQTLEKENAD----------------- 1235
Query: 5422 AQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLE 5601
L +L V GQ K ++LE +L + + D +RA + + +
Sbjct: 1236 ------------LAGELRVLGQAKQEVEHKKKKLEVQLQELQSKCSDGERARAELNDKVH 1283
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
K + ++ L EAE + + + ++ + D + ++ TR+ +N
Sbjct: 1284 KLQNEVESVTGMLSEAEGKAIKLAKEVASLGSQLQDTQELLQEETRQKLN 1333
>gi|20070691|gb|AAH26142.1| Myh11 protein [Mus musculus]
Length = 1972
Score = 1757 bits (4550), Expect = 0.0
Identities = 910/1926 (47%), Positives = 1297/1926 (67%), Gaps = 13/1926 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
D ++L V + + P A W +KL WVP + +GF SIK E DEV+VELV+ ++V
Sbjct: 10 DEKFLFVDKNFMNSPMAQADWVAKKLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKV 69
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
T+ +DD+QK NPPKF K+EDM+ELT LNEASVLHNL++RY+S LIYTYSGLFCVV+NPYK
Sbjct: 70 TVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYK 129
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
LPIYSE +++ +KGKKRHEMPPHI+AIADTAYRSMLQ+REDQSILCTGESGAGKTENTK
Sbjct: 130 YLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTK 189
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVIQYLA VA + + K ++ GELE QLLQANPILEAFGN+KTVK
Sbjct: 190 KVIQYLAVVASSHKGKKDSSIT--------------GELEKQLLQANPILEAFGNAKTVK 235
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
NDNSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFY +L G K
Sbjct: 236 NDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYLLAGAKEKM 295
Query: 907 KSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLL 1086
KS+ LLE ++Y FL N + +P D + F T+ +M IMGF ++E +I++VVS+VL
Sbjct: 296 KSDLLLESFNSYTFLSNGFVPIPAAQDDEMFQETLEAMSIMGFNEEEQLAILKVVSSVLQ 355
Query: 1087 LGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQE 1266
LGN+ F +E+ +DQA + D+ QKVCHL+G+ V + +A L PRIKVGR+ V KAQ +E
Sbjct: 356 LGNIVFKKERNTDQASMPDNTAAQKVCHLVGINVTDFTRAILTPRIKVGRDVVQKAQTKE 415
Query: 1267 QAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQIC 1446
QA+FA+EA+AKA+YERLF+W+++R+NK+LD+THRQGASF+GILDIAGFEIF++NSFEQ+C
Sbjct: 416 QADFAIEALAKATYERLFRWILSRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLC 475
Query: 1447 INYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEK---PMGVLALL 1617
INYTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP I+LIE+ P GVLALL
Sbjct: 476 INYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALL 535
Query: 1618 DEECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKN 1794
DEEC FPKA DKSFVEKL HPKF P ++ K+ F+++HYAG+VDY+A WL KN
Sbjct: 536 DEECWFPKATDKSFVEKLCSEQGNHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKN 595
Query: 1795 MDPLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQ 1962
MDPLN+NV L+ S+D FVA +WKD + G+ A+M E++ +++KGMFRTV Q
Sbjct: 596 MDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQ 655
Query: 1963 LHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGF 2142
L+KEQL KLMTTLRNT+P+FVRCIIPNHEK+SGK+++ LVLEQLRCNGVLEGIRICRQGF
Sbjct: 656 LYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGF 715
Query: 2143 PNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVL 2322
PNR+ FQEFR RYEIL + IPK F+DGK++ MI AL++D NLYRIGQSK+FFRTGVL
Sbjct: 716 PNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVL 775
Query: 2323 AHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWW 2502
AHLEEERDLK+T +IM FQA CRG+L+R+ +T N AYLKLRNWQWW
Sbjct: 776 AHLEEERDLKITDVIMAFQAMCRGYLARKAFTKRQQQLTAMKVIQRNCAAYLKLRNWQWW 835
Query: 2503 RLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQ 2682
RLFTKVKPLLQVTR ++E++AK++E++ KER K E + +E E+K Q+ E+ ++QEQ
Sbjct: 836 RLFTKVKPLLQVTRQEEEMQAKEEEMQKIKERQQKAETELKELEQKHTQLAEEKTLLQEQ 895
Query: 2683 LQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDX 2862
LQ E+E AE +++R RL + QELE I+++M RL R+K + + D
Sbjct: 896 LQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDL 955
Query: 2863 XXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQL 3042
+K + D LTT L
Sbjct: 956 EEQLEEEEAARQKLQLEKVTAEAKIKKLEDDILVMDDQNSKLSKERKLLEERVSDLTTNL 1015
Query: 3043 LDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKM 3222
+ EE+AK+ K K + E+ + ELE L +E + + ELE+ KRKL + D + +A+
Sbjct: 1016 AEEEEKAKNLTKLKSKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQ 1075
Query: 3223 GKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARN 3402
++ EL QL K++EELQ L R DEE K++R+++ I +L+ED+++ER ARN
Sbjct: 1076 AQIAELKMQLAKKEEELQAALARLDEEITQKNNALKKIRELEGHISDLQEDLDSERAARN 1135
Query: 3403 KAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIE 3582
KAE +R++ +LE +K ++ D +D Q+L +++++EV K+A+++ + E +++
Sbjct: 1136 KAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQ 1195
Query: 3583 EQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRK 3762
E + K ++ VEEL +Q+EQ K+ ++ L+K + ++E AD+A E+ +L ++ +++ K+K
Sbjct: 1196 EMRQKHTQAVEELTEQLEQFKRAKANLDKSKQTLEKENADLAGELRVLGQAKQEVEHKKK 1255
Query: 3763 IHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXX 3942
E L ++Q+ ++ + + L D++ + ++E++ + + E E + + +A+
Sbjct: 1256 KLEVQLQDLQSKCSDGERARAELSDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLGS 1315
Query: 3943 XXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGE 4122
TR K+ + RQLEDE+N+L D+ +E + +LE+ + +
Sbjct: 1316 QLQDTQELLQEETRQKLNVSTKLRQLEDERNSLQDQLDEEMEAKQNLERHVSTLNIQLSD 1375
Query: 4123 ARRKAEE--SVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSME 4296
+++K ++ S + +EE +K+ +++E L +Q EE A +++ ++K ++QQEL+D ++
Sbjct: 1376 SKKKLQDFASTIEVMEEGKKRLQKEMEGLSQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1435
Query: 4297 LENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIM 4476
L+N R + EK+QKKF+ +AEE+ K +RD E R++ET+ LSL ++
Sbjct: 1436 LDNQRQLVSNLEKKQKKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 1495
Query: 4477 KEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNL 4656
E EE +R + L+ E++D +S+KDD GKNVHELEK+KR+LE ++ +M+ Q+EELED L
Sbjct: 1496 LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDEL 1555
Query: 4657 QIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGA 4836
Q EDA+LRLEV QALK + +R + +D + EEKRR L +Q+ + E ELE+E++ ++ A
Sbjct: 1556 QATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALA 1615
Query: 4837 VSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALL 5016
+ +KK+E + +LE Q + A + +EE ++Q E ++AR ++++I A
Sbjct: 1616 AAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELDDARASRDEIFATS 1675
Query: 5017 READRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRA---KGGGISSEEKRRLE 5187
+E ++K +++EA+ QL+E +ARKQ A G +EKRRLE
Sbjct: 1676 KENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNTLQDEKRRLE 1735
Query: 5188 AKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNR 5367
A+IAQ Q N E D+ RKA +Q EQ++ +L+ ER+ QK E+ +Q LER N+
Sbjct: 1736 ARIAQLEEELEEEQGNMEAMSDRVRKATLQAEQLSNELATERSTAQKNESARQQLERQNK 1795
Query: 5368 DYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTT 5547
+ ++K+ E+E +++ ++ +AALEAK+ LE+Q+ E +EK AA ++ ++ +K+L +
Sbjct: 1796 ELRSKLQEVEGAVKAKLKSTVAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEVL 1855
Query: 5548 QQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANE 5727
Q EDE++ EQ KE EK N K + L+RQL+EAE+E R R +QRE D+ ++NE
Sbjct: 1856 LQVEDERKMAEQYKEQAEKGNTKVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNE 1915
Query: 5728 QLTREL 5745
+ RE+
Sbjct: 1916 AMGREV 1921
Score = 161 bits (407), Expect = 2e-37
Identities = 197/925 (21%), Positives = 387/925 (41%), Gaps = 68/925 (7%)
Frame = +1
Query: 2512 TKVKPLLQVTRTDDEIRAKDDEL-RATKERLL-KMEHDFRENEKKLDQVIVERAVIQEQL 2685
TK+K + ++ E+R K +E R E+L K+E D + +++ + + A ++ QL
Sbjct: 1026 TKLKSKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQL 1085
Query: 2686 -QQESENSAELDDIRGRLQTRN------QELEYIVNDMRDRLSXXXXXXXXXXXXRRKQM 2844
++E E A L + + +N +ELE ++D+++ L +R
Sbjct: 1086 AKKEEELQAALARLDEEITQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLG 1145
Query: 2845 ETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXX 3024
E + + +Q +++
Sbjct: 1146 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHTQAV 1205
Query: 3025 GLTTQLLDHEERAKHGV-KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSK 3201
T+ L+ +RAK + K+K LE + +L +L Q K E+E K+KL +L+D +
Sbjct: 1206 EELTEQLEQFKRAKANLDKSKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEVQLQDLQ 1265
Query: 3202 DHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDME 3381
++ EL++++ K E++ +E + K + + + + + +E ++
Sbjct: 1266 SKCSDGERARAELSDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLGSQLQDTQELLQ 1325
Query: 3382 TERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNA----TKRAIE 3549
E R K ++ + + QLE + + D++DE + + R +N +K+ ++
Sbjct: 1326 EE--TRQKLNVSTK--LRQLEDERNSLQDQLDEEMEAKQNLERHVSTLNIQLSDSKKKLQ 1381
Query: 3550 QIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQ 3729
T+E +EE K + +++E L Q E+ +LEK +N+ QE D+ ++ +
Sbjct: 1382 DFASTIE-VMEEGKKRLQKEMEGLSQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1440
Query: 3730 ASRADIDKKRKIHEAHLMEIQANLAE--SDEHKRTLIDQLERSRDELDHLNRVREEEEHA 3903
++++KK+K + L E + N++ +DE R + E+ L L R EE A
Sbjct: 1441 QLVSNLEKKQKKFDQLLAE-EKNISSKYADERDRAEAEAREKETKALS-LARALEEALEA 1498
Query: 3904 FANMQR--RLATAXXXXXXXXXXXXXXTRLKIANINRA------------RQLEDEKNAL 4041
++R ++ A ++ RA +LEDE A
Sbjct: 1499 KEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1558
Query: 4042 LDEKEEAE----GLRAHLEKEIHAARQGAGEARRKAEESVNQQLEEL------------- 4170
D K E L+ E+++ A + E RR+ + +++ EL
Sbjct: 1559 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1618
Query: 4171 RKKNLRDVEHLQKQLEESEVAKERILQSKKKIQ-------QELEDSSMELENVRASHRDS 4329
+KK D++ L+ Q + + +E ++ +K+Q +EL+D+ + + A+ +++
Sbjct: 1619 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELDDARASRDEIFATSKEN 1678
Query: 4330 EKRQKKFES---QMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESD 4500
EK+ K E+ Q+ E+ A ++A D +EL + LS N + K LE
Sbjct: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNTLQDEKRRLEA-- 1736
Query: 4501 RVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARL 4680
R+ + L++EL++ N + V KA E N++ + + N E AR
Sbjct: 1737 RIAQ-LEEELEEEQGNMEAMSDRV---RKATLQAEQLSNELATERSTAQKN----ESARQ 1788
Query: 4681 RLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIE 4860
+LE N+ L+S+ + + L +I LE ++E E R K A K+ +
Sbjct: 1789 QLERQNKELRSKLQEVEGAVKAKLKSTVAALEAKIAQLEEQVEQEAREKQAATKSLKQKD 1848
Query: 4861 NQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKF- 5037
++ E+ Q+E ++ E+Y + + + EEA + + I A R+ R+
Sbjct: 1849 KKLKEVLLQVEDERKMAEQYKEQAEKGNTKVKQLKRQLEEAEEESQRINANRRKLQRELD 1908
Query: 5038 ----------RAVEAEREQLREANE 5082
R V A + +LR NE
Sbjct: 1909 EATESNEAMGREVNALKSKLRRGNE 1933
Score = 95.9 bits (237), Expect = 1e-17
Identities = 119/601 (19%), Positives = 233/601 (37%), Gaps = 39/601 (6%)
Frame = +1
Query: 4066 GLRAHLEKE-------IHAARQGA--GEARRKAEESVNQQLEELR--KKNLRDVEHLQKQ 4212
G+ AHLE+E + A Q G RKA QQL ++ ++N L+
Sbjct: 773 GVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFTKRQQQLTAMKVIQRNCAAYLKLRNW 832
Query: 4213 LEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFE---SQMAEERVAV 4383
K + L + ++E++ E++ ++ + +E K+ E +Q+AEE+ +
Sbjct: 833 QWWRLFTKVKPLLQVTRQEEEMQAKEEEMQKIKERQQKAETELKELEQKHTQLAEEKTLL 892
Query: 4384 QKALLDRDAMSQELRDRETRVLSLLNEVDI----MKEHLEESDRVRRSLQQELQDSISNK 4551
Q+ L + E + R+ + E++ M+ LEE + + LQ E +
Sbjct: 893 QEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQM 952
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAI 4731
D + + E E A++ L+ E ++++LED++ + +D +L + L+
Sbjct: 953 LDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDDILVMDDQNSKLSKERKLLEERVSDLT 1012
Query: 4732 SNKDVEAEEKRRGLLK-------QIRDLENELENEKRGKSGAVSHRKKIEN--------- 4863
+N E EEK + L K I +LE L+ E++ + ++K+E
Sbjct: 1013 TNL-AEEEEKAKNLTKLKSKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQI 1071
Query: 4864 -----QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREAD 5028
QI EL+ QL + +EE + ++ R+ + I+ L + D
Sbjct: 1072 ADLQAQIAELKMQLA---KKEEELQAALARLDEEITQKNNALKKIRELEGHISDLQEDLD 1128
Query: 5029 RKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXX 5208
+ A +Q R+ E L + + + KR E + +
Sbjct: 1129 SERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQ------ELRAKREQEVTVLKKA 1182
Query: 5209 XXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKIT 5388
++ +Q+ Q +E++T L + + KQ+LE+ N D
Sbjct: 1183 LDEETRSHEAQVQEMRQKHTQA-VEELTEQLEQFKRAKANLDKSKQTLEKENAD------ 1235
Query: 5389 ELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEK 5568
L +L V GQ K ++LE +L D + D +
Sbjct: 1236 -----------------------LAGELRVLGQAKQEVEHKKKKLEVQLQDLQSKCSDGE 1272
Query: 5569 RANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
RA + + + K + ++ L+EAE + + ++ + D + ++ TR+ +
Sbjct: 1273 RARAELSDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLGSQLQDTQELLQEETRQKL 1332
Query: 5749 N 5751
N
Sbjct: 1333 N 1333
>gi|625305|pir||A61231 myosin heavy chain nonmuscle form A - human
Length = 1961
Score = 1755 bits (4545), Expect = 0.0
Identities = 911/1925 (47%), Positives = 1286/1925 (66%), Gaps = 14/1925 (0%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL V + + +P A WA +KL WVP GF S+K E + VELV+ ++V +
Sbjct: 8 KYLYVDKNFINNPLAQADWAAKKLVWVPSDKSGFEPASLKEEVGERGHVELVENGKKVKV 67
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDM+ELT LNEASVLHNLK+RYYS LIYTYSGLFCVVINPYK L
Sbjct: 68 NKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNL 127
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYSE+++E +KGKKRHEMPPHI+AI DTAYRSM+Q+REDQSILCTGESGAGKTENTKKV
Sbjct: 128 PIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKV 187
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
IQYLA+VA + ++K GELE QLLQANPILEAFGN+KTVKND
Sbjct: 188 IQYLAYVASSHKSKKDQ-----------------GELERQLLQANPILEAFGNAKTVKND 230
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA++ER+FHIFY +L G K+
Sbjct: 231 NSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKT 290
Query: 913 EYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 1092
+ LLE + YRFL N +T+P D F T+ +MRIMG ++E ++RV+S VL LG
Sbjct: 291 DLLLEPYNKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLG 350
Query: 1093 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA 1272
N+ F +E+ +DQA + D+ QKV HLLG+ V + + L PRIKVGR++V KAQ +EQA
Sbjct: 351 NIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQA 410
Query: 1273 EFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICIN 1452
+FA+EA+AKA+YER+F+WLV RINK+LD+T RQGASFIGILDIAGFEIFD+NSFEQ+CIN
Sbjct: 411 DFAIEALAKATYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCIN 470
Query: 1453 YTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDE 1623
YTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP IDLIEKP G+LALLDE
Sbjct: 471 YTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDE 530
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMD 1800
EC FPKA DKSFVEK+ + HPKF P ++ K+ F ++HYAG+VDY AD+WLMKNMD
Sbjct: 531 ECWFPKATDKSFVEKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMD 590
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQLH 1968
PLN+N+ L+ S+D FV+ +WKD + G+ A M+ETA ++RKGMFRTV QL+
Sbjct: 591 PLNDNIATLLHQSSDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLY 650
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
KEQL KLM +LRNT+P+FVRCIIPNHEKK+GK++ +LVL+QLRCNGVLEGIRICRQGFPN
Sbjct: 651 KEQLAKLMASLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPN 710
Query: 2149 RVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAH 2328
RV FQEFR RYEILTP+ IPK F+DGK++ MI AL++D+NLYRIGQSKVFFR GVLAH
Sbjct: 711 RVVFQEFRQRYEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAH 770
Query: 2329 LEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRL 2508
LEEERDLK+T +I+ FQA CRG+L+R+ + N AYLKLRNWQWWRL
Sbjct: 771 LEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRL 830
Query: 2509 FTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQ 2688
FTKVKPLLQV+R ++E+ AK++EL +E+ L E+ E E Q++ E+ +QEQLQ
Sbjct: 831 FTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLMEMETLQSQLMAEKLQLQEQLQ 890
Query: 2689 QESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXX 2868
E+E AE +++R RL + QELE I +D+ R+ ++K + +++
Sbjct: 891 AETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERYQHLQAEKKKMQQNIQELEE 950
Query: 2869 XXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLD 3048
+K + +D TT L +
Sbjct: 951 QLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTE 1010
Query: 3049 HEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGK 3228
EE++K K K + E + +LE+ L RE + + ELE+ +RKL + D D +AE +
Sbjct: 1011 EEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQ 1070
Query: 3229 VEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKA 3408
+ EL QL K++EELQ L R +EE+A + K++R++++ I EL+ED+E+ER +RNKA
Sbjct: 1071 IAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKA 1130
Query: 3409 EMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQ 3588
E +R++ +LE +K ++ D +D Q+L S++++EVN K+ +E+ T E +I+E
Sbjct: 1131 EKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEM 1190
Query: 3589 KAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIH 3768
+ K S+ VEEL +Q+EQ K+ ++ LEK + + ER ++A E+ +L D + KRK
Sbjct: 1191 RQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGGRDSEHKRKKV 1250
Query: 3769 EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXX 3948
EA L E+Q E + + L D++ + + ELD++ + + + + + + +
Sbjct: 1251 EAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQL 1310
Query: 3949 XXXXXXXXXXTRLKIANINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHAARQGAGEA 4125
R K++ + +Q+EDEKN+ ++ +EE E + +LEK+I +
Sbjct: 1311 QDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEEAKHNLEKQIATLHAQVADM 1370
Query: 4126 RRKAEESVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMEL 4299
++K E+SV + EE+++K +D+E L ++ EE A +++ ++K ++QQEL+D ++L
Sbjct: 1371 KKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDL 1430
Query: 4300 ENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMK 4479
++ R S + EK+QKKF+ +AEE+ K +RD E R++ET+ LSL ++
Sbjct: 1431 DHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAM 1490
Query: 4480 EHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQ 4659
E E +R+ + + E++D +S+KDD GK+VHELEK+KR+LE ++ +M+ Q+EELED LQ
Sbjct: 1491 EQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQ 1550
Query: 4660 IAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAV 4839
EDA+LRLEV QA+K++ +R + +D ++EEK++ L++Q+R++E ELE+E++ +S AV
Sbjct: 1551 ATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAV 1610
Query: 4840 SHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLR 5019
+ RKK+E + +LE ++ AN+ ++E + E ++ R ++E+I A +
Sbjct: 1611 AARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAK 1670
Query: 5020 EADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKG---GGISSEEKRRLEA 5190
E ++K +++EAE QL+E +A++Q A G ++ EEKRRLEA
Sbjct: 1671 ENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEA 1730
Query: 5191 KIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRD 5370
+IAQ Q N EL D+ +KA +Q++QI DL++ER QK E +Q LER N++
Sbjct: 1731 RIAQLEEELEEEQGNTELINDRLKKANLQIDQINADLNLERGHAQKNENARQQLERQNKE 1790
Query: 5371 YKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQ 5550
K K+ E+E +S+ +A + ALEAK+ LE+QL+ E +E+ AA + RR EK+L D
Sbjct: 1791 LKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLL 1850
Query: 5551 QFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQ 5730
Q +DE+R EQ K+ +K++ + + L+RQL+EAE+E R R +QRE +D + +
Sbjct: 1851 QVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADA 1910
Query: 5731 LTREL 5745
+ RE+
Sbjct: 1911 MNREV 1915
Score = 58.9 bits (141), Expect = 1e-06
Identities = 70/400 (17%), Positives = 156/400 (38%), Gaps = 15/400 (3%)
Frame = +1
Query: 2533 QVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQ-----LQQES 2697
QV ++ +DEL+AT++ L++E + + + + ++ + R E+ ++Q
Sbjct: 1534 QVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVR 1593
Query: 2698 ENSAELDDIRGRLQ---TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXX 2868
E AEL+D R + ++LE + D+ + RK ++D
Sbjct: 1594 EMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMR 1653
Query: 2869 XXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLD 3048
++ Q+ L ++ +
Sbjct: 1654 ELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIAN 1713
Query: 3049 HEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMG- 3225
+ ++ K RLE ++ +LE++L E+ + +K +++ L + G
Sbjct: 1714 SSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINADLNLERGH 1773
Query: 3226 --KVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNAR 3399
K E QL ++++EL+ +L + E + + + ++ I +L E ++ E R
Sbjct: 1774 AQKNENARQQLERQNKELKVKLQ--EMEGTVKSKYKASITALEAKIAQLEEQLDNETKER 1831
Query: 3400 NKAEMTRREVVAQLEKVKGDVLDKVDE----ATMLQDLMSRKDEEVNATKRAIEQIQHTM 3567
A + V + EK DVL +VD+ A +D + + KR +E+ +
Sbjct: 1832 QAA----CKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEA 1887
Query: 3568 EGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQAD 3687
+ + + K R++E+ + + ++ S L+ + + D
Sbjct: 1888 Q-RANASRRKLQRELEDATETADAMNREVSSLKNKLRRGD 1926
>gi|6981236|ref|NP_037326.1| myosin, heavy polypeptide 9; Myosin,
heavy polypeptide 9, non-muscle; Myosin heavy polypeptide
9 non-muscle [Rattus norvegicus]
gi|13431671|sp|Q62812|MYH9_RAT Myosin heavy chain, nonmuscle type A
(Cellular myosin heavy chain, type A) (Nonmuscle myosin
heavy chain-A) (NMMHC-A)
gi|967249|gb|AAA74950.1| nonmuscle myosin heavy chain-A
Length = 1961
Score = 1751 bits (4535), Expect = 0.0
Identities = 909/1925 (47%), Positives = 1283/1925 (66%), Gaps = 14/1925 (0%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL V + + +P A +KL WVP GF S+K E +E +VELV+ ++V +
Sbjct: 8 KYLYVDKNFINNPLAQADCGAKKLVWVPSTKNGFEPASLKEEVGEEAIVELVENGKKVKV 67
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDM+ELT LNEASVLHNLK+RYYS LIYTYSGLFCVVINPYK L
Sbjct: 68 NKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNL 127
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYSE++++ +KGKKRHEMPPHI+AI DTAYRSM+Q+REDQSILCTGESGAGKTENTKKV
Sbjct: 128 PIYSEEIVDMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKV 187
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
IQYLAHVA + ++K GELE QLLQANPILEAFGN+KTVKND
Sbjct: 188 IQYLAHVASSHKSKKDQ-----------------GELERQLLQANPILEAFGNAKTVKND 230
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA++ER+FHIFY +L G K+
Sbjct: 231 NSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKT 290
Query: 913 EYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 1092
+ LLE + YRFL N +T+P D F T+ +MRIMG +DE ++RV+S VL LG
Sbjct: 291 DLLLEPYNKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPEDEQMGLLRVISGVLQLG 350
Query: 1093 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA 1272
N+ F +E+ +DQA + D+ QKV HLLG+ V + + L PRIKVGR++V KAQ +EQA
Sbjct: 351 NIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQA 410
Query: 1273 EFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICIN 1452
+FA+EA+AKA+YER+F+WLV RINK+LD+T RQGASFIGILDIAGFEIFD+NSFEQ+CIN
Sbjct: 411 DFAIEALAKATYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCIN 470
Query: 1453 YTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDE 1623
YTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP IDLIEKP G+LALLDE
Sbjct: 471 YTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDE 530
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMD 1800
EC FPKA DKSFVEK+ + HPKF P ++ K+ F ++HYAG+VDY AD+WLMKNMD
Sbjct: 531 ECWFPKATDKSFVEKVVQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMD 590
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQLH 1968
PLN+N+ L+ S+D FV+ +WKD + G+ A M+ETA ++RKGMFRTV QL+
Sbjct: 591 PLNDNIATLLHQSSDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLY 650
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
KEQL KLM TLRNT+P+FV CIIPNHEKK+GK++ +LVL+QLRCNGVLEGIRICRQGFPN
Sbjct: 651 KEQLAKLMATLRNTNPNFVCCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPN 710
Query: 2149 RVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAH 2328
RV FQEFR RYEILTP+ IPK F+DGK++ MI AL++D+NLYRIGQSKVFFR+GVLAH
Sbjct: 711 RVVFQEFRQRYEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRSGVLAH 770
Query: 2329 LEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRL 2508
LEEERDLK+T +I+ FQA CRG+L+R+ + N AYL+LRNWQWWRL
Sbjct: 771 LEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLRLRNWQWWRL 830
Query: 2509 FTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQ 2688
FTKVKPLL R +DE+ AK+ EL +E+ L E+ E E Q++ E+ +QEQLQ
Sbjct: 831 FTKVKPLLNSIRHEDELLAKEAELTKVREKHLAAENRLTEMETMQSQLMAEKLQLQEQLQ 890
Query: 2689 QESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXX 2868
++E AE +++R RL + QELE I +D+ R+ ++K + +++
Sbjct: 891 AKTELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQYLQAEKKKMQQNIQELEE 950
Query: 2869 XXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLD 3048
+K + +D TT L++
Sbjct: 951 QLEEEESARQKLQLEKVTTEAKLKKLEEDQIIMEDQNCKLAKEKKLLEDRVAEFTTDLME 1010
Query: 3049 HEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGK 3228
EE++K K K + E + +LE+ L RE + + ELE+ +RKL + D D +AE +
Sbjct: 1011 EEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQ 1070
Query: 3229 VEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKA 3408
+ EL QL K++EELQ L R +EE+A + K++R+++T I EL+ED+E+ER RNKA
Sbjct: 1071 IAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELETQISELQEDLESERACRNKA 1130
Query: 3409 EMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQ 3588
E +R++ +LE +K ++ D +D Q+L S++++EV+ K+ +E T E +I+E
Sbjct: 1131 EKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVSILKKTLEDEAKTHEAQIQEM 1190
Query: 3589 KAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIH 3768
+ K S+ VEEL +Q+EQ K+ ++ LEK + + ER ++A E+ L + D + KRK
Sbjct: 1191 RQKHSQAVEELAEQLEQTKRVKATLEKAKQTLENERGELANEVKALLQGKGDSEHKRKKV 1250
Query: 3769 EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXX 3948
EA L E+Q +E + + L D++ + + ELD + + + + + + + +
Sbjct: 1251 EAQLQELQVKFSEGERVRTELADKVSKLQVELDSVTGLLNQSDSKSSKLTKDFSALESQL 1310
Query: 3949 XXXXXXXXXXTRLKIANINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHAARQGAGEA 4125
R K++ + +Q+EDEKN+ ++ +EE E + +LEK+I +
Sbjct: 1311 QDTQELLQEENRQKLSLSTKLKQMEDEKNSFREQLEEEEEEAKRNLEKQIATLHAQVTDM 1370
Query: 4126 RRKAEESVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMEL 4299
++K E+ V + EE +++ +D+E L ++LEE A +++ ++K ++QQEL+D ++L
Sbjct: 1371 KKKMEDGVGCLETAEEAKRRLQKDLEGLSQRLEEKVAAYDKLEKTKTRLQQELDDLLVDL 1430
Query: 4300 ENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMK 4479
++ R S + EK+QKKF+ +AEE+ K +RD E R++ET+ LSL ++
Sbjct: 1431 DHQRQSVSNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAM 1490
Query: 4480 EHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQ 4659
E E +R+ + + E++D +S+KDD GK+VHELEK+ R+LE ++ +M+ Q+EELED LQ
Sbjct: 1491 EQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSNRALEQQVEEMKTQLEELEDELQ 1550
Query: 4660 IAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAV 4839
EDA+LRLEV QA+K++ +R + +D ++EEK++ L++Q+R++E ELE+E++ +S A+
Sbjct: 1551 ATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSIAM 1610
Query: 4840 SHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLR 5019
+ RKK+E + +LE ++ AN+ +EE + + ++ R ++E+I A +
Sbjct: 1611 AARKKLEMDLKDLEAHIDTANKNREEAIKQLRKLQAQMKDCMRDVDDTRASREEILAQAK 1670
Query: 5020 EADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKG---GGISSEEKRRLEA 5190
E ++K +++EAE QL+E +A++Q A G ++ EEKRRLEA
Sbjct: 1671 ENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEA 1730
Query: 5191 KIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRD 5370
IA Q N EL D+ +KA +Q++QI TDL++ER+ QK E +Q LER N++
Sbjct: 1731 LIALLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKE 1790
Query: 5371 YKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQ 5550
KAK+ E+ES +S+ +A +AALEAK+ LE+QL+ E +E+ AA++ RR EK+L D
Sbjct: 1791 LKAKLQEMESAVKSKYKASIAALEAKIAQLEEQLDNETKERQAASKQVRRAEKKLKDVLL 1850
Query: 5551 QFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQ 5730
Q EDE+R EQ K+ +K++ + + L+RQL+EAE+E R R +QRE +D + +
Sbjct: 1851 QVEDERRNAEQFKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADA 1910
Query: 5731 LTREL 5745
+ RE+
Sbjct: 1911 MNREV 1915
Score = 110 bits (274), Expect = 5e-22
Identities = 130/646 (20%), Positives = 269/646 (41%), Gaps = 48/646 (7%)
Frame = +1
Query: 2554 EIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGR 2733
+ A + +L+ T+E L + KL Q+ E+ +EQL++E E + +
Sbjct: 1302 DFSALESQLQDTQELLQEENRQKLSLSTKLKQMEDEKNSFREQLEEEEEEA------KRN 1355
Query: 2734 LQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXD 2913
L+ + L V DM+ ++ +R+ + +
Sbjct: 1356 LEKQIATLHAQVTDMKKKMEDGVGCLETAEEAKRRLQKDLEGLSQRLEEKVAAYDKLEKT 1415
Query: 2914 KTNVDQXXXXXXXXXXXXQDAY---DXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAK 3084
KT + Q + + + ++ + + +RA+ + K
Sbjct: 1416 KTRLQQELDDLLVDLDHQRQSVSNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREK 1475
Query: 3085 GRLENQLHELEQDLNRERQYKSELEQHKRKLLAELED---SKDHLAEKMGKVEELNNQLM 3255
E + L + L + K+ELE+ ++ E+ED SKD + + + ++E+ N L
Sbjct: 1476 ---ETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSNRALE 1532
Query: 3256 KRDEELQHQLTRYDEE-----------SANVTLMQ----------------------KQM 3336
++ EE++ QL ++E N+ M+ +Q+
Sbjct: 1533 QQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQV 1592
Query: 3337 RDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKD 3516
R+M+ +++ R+ AR K EM +++ A ++ + + + + LQ M
Sbjct: 1593 REMEAELEDERKQRSIAMAARKKLEMDLKDLEAHIDTANKNREEAIKQLRKLQAQMKDCM 1652
Query: 3517 EEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQER 3696
+V+ T+ + E+I + K E+K K + ++ Q +++ + E+ + QA QER
Sbjct: 1653 RDVDDTRASREEI--LAQAKENEKKLK------SMEAEMIQLQEELAAAERAKRQAQQER 1704
Query: 3697 ADMAQEIALLQASRA-DIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHL 3873
++A EIA A +++KR++ EA + ++ L E + + D+L+++ ++D +
Sbjct: 1705 DELADEIANSSGKGALALEEKRRL-EALIALLEEELEEEQGNTELINDRLKKANLQIDQI 1763
Query: 3874 NR-VREEEEHAFAN------MQRRLATAXXXXXXXXXXXXXXTRLKIANIN-RARQLEDE 4029
N + E HA N ++R+ + IA + + QLE++
Sbjct: 1764 NTDLNLERSHAQKNENARQQLERQNKELKAKLQEMESAVKSKYKASIAALEAKIAQLEEQ 1823
Query: 4030 KNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQK 4209
+ E++ A EK++ + RR AE Q ++ K ++ L++
Sbjct: 1824 LDNETKERQAASKQVRRAEKKLKDVLLQVEDERRNAE-----QFKDQADKASTRLKQLKR 1878
Query: 4210 QLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKK 4347
QLEE+E +R S++K+Q+ELED++ E A +R+ + K
Sbjct: 1879 QLEEAEEEAQRANASRRKLQRELEDAT---ETADAMNREVSSLKNK 1921
>gi|7305295|ref|NP_038635.1| myosin heavy chain 11, smooth muscle [Mus
musculus]
gi|7441403|pir||JC5421 smooth muscle myosin heavy chain 2 - mouse
gi|1945080|dbj|BAA19691.1| myosin [Mus musculus]
Length = 1938
Score = 1744 bits (4516), Expect = 0.0
Identities = 904/1926 (46%), Positives = 1295/1926 (66%), Gaps = 13/1926 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
D ++L V + + P A W +KL WVP + +GF SIK E DEV+VELV+ ++V
Sbjct: 10 DEKFLFVDKNFMNSPMAQADWVAKKLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKV 69
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
T+ +DD+QK NPPKF K+EDM+ELT LNEASVLHNL++RY+S LIYTYSGLFCVV+NPYK
Sbjct: 70 TVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYK 129
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
LPIYSE +++ +KGKKRHEMPPHI+AIADTAYRSMLQ+REDQSILCTGESGAGKTENT+
Sbjct: 130 YLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTQ 189
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVIQYLA VA + + K ++ GELE QLLQANPILEAFGN+KTVK
Sbjct: 190 KVIQYLAVVASSHKGKKDSSIT--------------GELEKQLLQANPILEAFGNAKTVK 235
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
NDNSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFY +L G K
Sbjct: 236 NDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYLLAGAKEKM 295
Query: 907 KSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLL 1086
KS+ LLE ++Y FL N + +P D + F T+ +M IMGF ++E +I++VVS+VL
Sbjct: 296 KSDLLLESFNSYTFLSNGFVPIPAAQDDEMFQETLEAMSIMGFNEEEQLAILKVVSSVLQ 355
Query: 1087 LGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQE 1266
LGN+ F +E+ +DQA + D+ QKVCHL+G+ V + +A L PRIKVGR+ V KAQ +E
Sbjct: 356 LGNIVFKKERNTDQASMPDNTAAQKVCHLVGINVTDFTRAILTPRIKVGRDVVQKAQTKE 415
Query: 1267 QAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQIC 1446
QA+FA+EA+AKA+YERLF+W+++R+NK+LD+THRQGASF+GILDIAGFEIF++NSFEQ+C
Sbjct: 416 QADFAIEALAKATYERLFRWILSRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLC 475
Query: 1447 INYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEK---PMGVLALL 1617
INYTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP+I+LIE+ P GVLALL
Sbjct: 476 INYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPSIELIERPNNPPGVLALL 535
Query: 1618 DEECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKN 1794
DEEC FPKA DKSFVEKL HPKF P ++ K+ F+++HYAG+VDY+A WL KN
Sbjct: 536 DEECWFPKATDKSFVEKLCSEQGNHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKN 595
Query: 1795 MDPLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQ 1962
MDPLN+NV L+ S+D FVA +WKD + G+ A+M E++ +++KGMFRTV Q
Sbjct: 596 MDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQ 655
Query: 1963 LHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGF 2142
L+KEQL KLM TLRNT+ +FVRCIIPNHEK+SGK+++ LVLEQLRCNGVLEGIRICRQGF
Sbjct: 656 LYKEQLGKLMATLRNTTANFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGF 715
Query: 2143 PNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVL 2322
PNR+ FQEFR RYEIL + IPK F+DGK++ MI AL++D NLYRIGQSK+FFRTGVL
Sbjct: 716 PNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVL 775
Query: 2323 AHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWW 2502
AHLEEERDLK+T +IM FQA CRG+L+R+ +T N AYLKLRNWQWW
Sbjct: 776 AHLEEERDLKITDVIMAFQAMCRGYLARKAFTKRQQQLTAMKVIQRNCAAYLKLRNWQWW 835
Query: 2503 RLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQ 2682
RLFTKVKPLLQVTR ++E++AK++E++ ER K E + +E E+K Q+ E+ ++QEQ
Sbjct: 836 RLFTKVKPLLQVTRQEEEMQAKEEEMQKITERQQKAETELKELEQKHTQLAEEKTLLQEQ 895
Query: 2683 LQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDX 2862
LQ E+E AE +++R RL + QELE I+++M RL R+K + + D
Sbjct: 896 LQAETELYAESEEMRVRLAAKKQELEEILHEMEARLEEEEDRRQQLQAERKKMAQQMLDL 955
Query: 2863 XXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQL 3042
+K + D LTT L
Sbjct: 956 EEQLEEEEAARQKLQLEKVTAEAKIKKLEDDILVMDDQNSKLSKERKLLEERVSDLTTNL 1015
Query: 3043 LDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKM 3222
+ EE+AK+ K K + E+ + ELE L +E + + ELE+ KRKL + D + +A+
Sbjct: 1016 AEEEEKAKNLTKLKSKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQ 1075
Query: 3223 GKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARN 3402
++ EL QL K++EELQ L R DEE A K++R+++ I +L+ED+++ER ARN
Sbjct: 1076 AQIAELKMQLAKKEEELQAALARLDEEIAQKNNALKKIRELEGHISDLQEDLDSERAARN 1135
Query: 3403 KAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIE 3582
KAE +R++ +LE +K ++ D +D Q+L +++++EV K+A+++ + E +++
Sbjct: 1136 KAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQ 1195
Query: 3583 EQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRK 3762
E + K ++ VEEL +Q+EQ K+ ++ L+K + ++E AD+A E+ +L ++ +++ K+K
Sbjct: 1196 EMRQKHTQAVEELTEQLEQFKRAKANLDKSKQTLEKENADLAGELRVLGQAKQEVEHKKK 1255
Query: 3763 IHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXX 3942
E L ++Q+ ++ + + L D++ + ++E++ + + E E + + +A+
Sbjct: 1256 KLEVQLQDLQSKCSDGERARAELSDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLGS 1315
Query: 3943 XXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGE 4122
TR K+ + RQLEDE+N+L D+ +E + +LE+ + +
Sbjct: 1316 QLQDTQELLQEETRQKLNVSTKLRQLEDERNSLQDQLDEEMEAKQNLERHVSTLNIQLSD 1375
Query: 4123 ARRKAEE--SVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSME 4296
+++K ++ S + +EE +K+ +++E L +Q EE A +++ ++K ++QQEL+D ++
Sbjct: 1376 SKKKLQDFASTIEVMEEGKKRLQKEMEGLSQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1435
Query: 4297 LENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIM 4476
L+N R + EK+QKKF+ +AEE+ K +RD E R++ET+ LSL ++
Sbjct: 1436 LDNQRQLVSNLEKKQKKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 1495
Query: 4477 KEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNL 4656
E EE +R + L+ E++D +S+KDD GKNVHELEK+KR+LE ++ +M+ Q+EE ED++
Sbjct: 1496 LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEESEDDV 1555
Query: 4657 QIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGA 4836
Q EDA+LRLEV QALK + +R + +D + EEKRR L +Q+ + E ELE+E++ ++ A
Sbjct: 1556 QATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALA 1615
Query: 4837 VSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALL 5016
+ +KK+E + +LE Q + A + +EE ++Q E ++AR ++++I A
Sbjct: 1616 AAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELDDARASRDEIFATS 1675
Query: 5017 READRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRA---KGGGISSEEKRRLE 5187
+E ++K +++EA+ QL+E +ARKQ A G +EKRRLE
Sbjct: 1676 KENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNTLQDEKRRLE 1735
Query: 5188 AKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNR 5367
A+IAQ Q N E D+ RKA +Q EQ++ +L+ ER+ QK E+ +Q LER N+
Sbjct: 1736 ARIAQLEEELEEEQGNMEAMSDRVRKATLQAEQLSNELATERSTAQKNESARQQLERQNK 1795
Query: 5368 DYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTT 5547
+ ++K+ E+E +++ ++ +AALEAK+ LE+Q+ E +EK AA ++ ++ +K+L +
Sbjct: 1796 ELRSKLQEVEGAVKAKLKSTVAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEVL 1855
Query: 5548 QQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANE 5727
Q EDE++ EQ KE EK N K + L+RQL+EAE+E R +QRE D+ ++NE
Sbjct: 1856 LQVEDERKMAEQYKEQAEKGNTKVKQLKRQLEEAEEESQCINANRRKLQRELDEATESNE 1915
Query: 5728 QLTREL 5745
+ RE+
Sbjct: 1916 AMGREV 1921
Score = 97.1 bits (240), Expect = 5e-18
Identities = 120/601 (19%), Positives = 233/601 (37%), Gaps = 39/601 (6%)
Frame = +1
Query: 4066 GLRAHLEKE-------IHAARQGA--GEARRKAEESVNQQLEELR--KKNLRDVEHLQKQ 4212
G+ AHLE+E + A Q G RKA QQL ++ ++N L+
Sbjct: 773 GVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFTKRQQQLTAMKVIQRNCAAYLKLRNW 832
Query: 4213 LEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFE---SQMAEERVAV 4383
K + L + ++E++ E++ + + +E K+ E +Q+AEE+ +
Sbjct: 833 QWWRLFTKVKPLLQVTRQEEEMQAKEEEMQKITERQQKAETELKELEQKHTQLAEEKTLL 892
Query: 4384 QKALLDRDAMSQELRDRETRVLSLLNEVDI----MKEHLEESDRVRRSLQQELQDSISNK 4551
Q+ L + E + R+ + E++ M+ LEE + R+ LQ E +
Sbjct: 893 QEQLQAETELYAESEEMRVRLAAKKQELEEILHEMEARLEEEEDRRQQLQAERKKMAQQM 952
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAI 4731
D + + E E A++ L+ E ++++LED++ + +D +L + L+
Sbjct: 953 LDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDDILVMDDQNSKLSKERKLLEERVSDLT 1012
Query: 4732 SNKDVEAEEKRRGLLK-------QIRDLENELENEKRGKSGAVSHRKKIEN--------- 4863
+N E EEK + L K I +LE L+ E++ + ++K+E
Sbjct: 1013 TNL-AEEEEKAKNLTKLKSKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQI 1071
Query: 4864 -----QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREAD 5028
QI EL+ QL + +EE + ++ R+ + I+ L + D
Sbjct: 1072 ADLQAQIAELKMQLA---KKEEELQAALARLDEEIAQKNNALKKIRELEGHISDLQEDLD 1128
Query: 5029 RKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXX 5208
+ A +Q R+ E L + + + KR E + +
Sbjct: 1129 SERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQ------ELRAKREQEVTVLKKA 1182
Query: 5209 XXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKIT 5388
++ +Q+ Q +E++T L + + KQ+LE+ N D
Sbjct: 1183 LDEETRSHEAQVQEMRQKHTQA-VEELTEQLEQFKRAKANLDKSKQTLEKENAD------ 1235
Query: 5389 ELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEK 5568
L +L V GQ K ++LE +L D + D +
Sbjct: 1236 -----------------------LAGELRVLGQAKQEVEHKKKKLEVQLQDLQSKCSDGE 1272
Query: 5569 RANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
RA + + + K + ++ L+EAE + + ++ + D + ++ TR+ +
Sbjct: 1273 RARAELSDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLGSQLQDTQELLQEETRQKL 1332
Query: 5749 N 5751
N
Sbjct: 1333 N 1333
>gi|13431676|sp|O08638|MYHB_MOUSE Myosin heavy chain, smooth muscle
isoform (SMMHC)
gi|7441402|pir||JC5420 smooth muscle myosin heavy chain 1 - mouse
gi|1945078|dbj|BAA19690.1| myosin [Mus musculus]
Length = 1972
Score = 1744 bits (4516), Expect = 0.0
Identities = 904/1926 (46%), Positives = 1295/1926 (66%), Gaps = 13/1926 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
D ++L V + + P A W +KL WVP + +GF SIK E DEV+VELV+ ++V
Sbjct: 10 DEKFLFVDKNFMNSPMAQADWVAKKLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKV 69
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
T+ +DD+QK NPPKF K+EDM+ELT LNEASVLHNL++RY+S LIYTYSGLFCVV+NPYK
Sbjct: 70 TVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYK 129
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
LPIYSE +++ +KGKKRHEMPPHI+AIADTAYRSMLQ+REDQSILCTGESGAGKTENT+
Sbjct: 130 YLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTQ 189
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVIQYLA VA + + K ++ GELE QLLQANPILEAFGN+KTVK
Sbjct: 190 KVIQYLAVVASSHKGKKDSSIT--------------GELEKQLLQANPILEAFGNAKTVK 235
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
NDNSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFY +L G K
Sbjct: 236 NDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYLLAGAKEKM 295
Query: 907 KSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLL 1086
KS+ LLE ++Y FL N + +P D + F T+ +M IMGF ++E +I++VVS+VL
Sbjct: 296 KSDLLLESFNSYTFLSNGFVPIPAAQDDEMFQETLEAMSIMGFNEEEQLAILKVVSSVLQ 355
Query: 1087 LGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQE 1266
LGN+ F +E+ +DQA + D+ QKVCHL+G+ V + +A L PRIKVGR+ V KAQ +E
Sbjct: 356 LGNIVFKKERNTDQASMPDNTAAQKVCHLVGINVTDFTRAILTPRIKVGRDVVQKAQTKE 415
Query: 1267 QAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQIC 1446
QA+FA+EA+AKA+YERLF+W+++R+NK+LD+THRQGASF+GILDIAGFEIF++NSFEQ+C
Sbjct: 416 QADFAIEALAKATYERLFRWILSRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLC 475
Query: 1447 INYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEK---PMGVLALL 1617
INYTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP+I+LIE+ P GVLALL
Sbjct: 476 INYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPSIELIERPNNPPGVLALL 535
Query: 1618 DEECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKN 1794
DEEC FPKA DKSFVEKL HPKF P ++ K+ F+++HYAG+VDY+A WL KN
Sbjct: 536 DEECWFPKATDKSFVEKLCSEQGNHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKN 595
Query: 1795 MDPLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQ 1962
MDPLN+NV L+ S+D FVA +WKD + G+ A+M E++ +++KGMFRTV Q
Sbjct: 596 MDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQ 655
Query: 1963 LHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGF 2142
L+KEQL KLM TLRNT+ +FVRCIIPNHEK+SGK+++ LVLEQLRCNGVLEGIRICRQGF
Sbjct: 656 LYKEQLGKLMATLRNTTANFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGF 715
Query: 2143 PNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVL 2322
PNR+ FQEFR RYEIL + IPK F+DGK++ MI AL++D NLYRIGQSK+FFRTGVL
Sbjct: 716 PNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVL 775
Query: 2323 AHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWW 2502
AHLEEERDLK+T +IM FQA CRG+L+R+ +T N AYLKLRNWQWW
Sbjct: 776 AHLEEERDLKITDVIMAFQAMCRGYLARKAFTKRQQQLTAMKVIQRNCAAYLKLRNWQWW 835
Query: 2503 RLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQ 2682
RLFTKVKPLLQVTR ++E++AK++E++ ER K E + +E E+K Q+ E+ ++QEQ
Sbjct: 836 RLFTKVKPLLQVTRQEEEMQAKEEEMQKITERQQKAETELKELEQKHTQLAEEKTLLQEQ 895
Query: 2683 LQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDX 2862
LQ E+E AE +++R RL + QELE I+++M RL R+K + + D
Sbjct: 896 LQAETELYAESEEMRVRLAAKKQELEEILHEMEARLEEEEDRRQQLQAERKKMAQQMLDL 955
Query: 2863 XXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQL 3042
+K + D LTT L
Sbjct: 956 EEQLEEEEAARQKLQLEKVTAEAKIKKLEDDILVMDDQNSKLSKERKLLEERVSDLTTNL 1015
Query: 3043 LDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKM 3222
+ EE+AK+ K K + E+ + ELE L +E + + ELE+ KRKL + D + +A+
Sbjct: 1016 AEEEEKAKNLTKLKSKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQ 1075
Query: 3223 GKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARN 3402
++ EL QL K++EELQ L R DEE A K++R+++ I +L+ED+++ER ARN
Sbjct: 1076 AQIAELKMQLAKKEEELQAALARLDEEIAQKNNALKKIRELEGHISDLQEDLDSERAARN 1135
Query: 3403 KAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIE 3582
KAE +R++ +LE +K ++ D +D Q+L +++++EV K+A+++ + E +++
Sbjct: 1136 KAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQ 1195
Query: 3583 EQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRK 3762
E + K ++ VEEL +Q+EQ K+ ++ L+K + ++E AD+A E+ +L ++ +++ K+K
Sbjct: 1196 EMRQKHTQAVEELTEQLEQFKRAKANLDKSKQTLEKENADLAGELRVLGQAKQEVEHKKK 1255
Query: 3763 IHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXX 3942
E L ++Q+ ++ + + L D++ + ++E++ + + E E + + +A+
Sbjct: 1256 KLEVQLQDLQSKCSDGERARAELSDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLGS 1315
Query: 3943 XXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGE 4122
TR K+ + RQLEDE+N+L D+ +E + +LE+ + +
Sbjct: 1316 QLQDTQELLQEETRQKLNVSTKLRQLEDERNSLQDQLDEEMEAKQNLERHVSTLNIQLSD 1375
Query: 4123 ARRKAEE--SVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSME 4296
+++K ++ S + +EE +K+ +++E L +Q EE A +++ ++K ++QQEL+D ++
Sbjct: 1376 SKKKLQDFASTIEVMEEGKKRLQKEMEGLSQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1435
Query: 4297 LENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIM 4476
L+N R + EK+QKKF+ +AEE+ K +RD E R++ET+ LSL ++
Sbjct: 1436 LDNQRQLVSNLEKKQKKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 1495
Query: 4477 KEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNL 4656
E EE +R + L+ E++D +S+KDD GKNVHELEK+KR+LE ++ +M+ Q+EE ED++
Sbjct: 1496 LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEESEDDV 1555
Query: 4657 QIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGA 4836
Q EDA+LRLEV QALK + +R + +D + EEKRR L +Q+ + E ELE+E++ ++ A
Sbjct: 1556 QATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALA 1615
Query: 4837 VSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALL 5016
+ +KK+E + +LE Q + A + +EE ++Q E ++AR ++++I A
Sbjct: 1616 AAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELDDARASRDEIFATS 1675
Query: 5017 READRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRA---KGGGISSEEKRRLE 5187
+E ++K +++EA+ QL+E +ARKQ A G +EKRRLE
Sbjct: 1676 KENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNTLQDEKRRLE 1735
Query: 5188 AKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNR 5367
A+IAQ Q N E D+ RKA +Q EQ++ +L+ ER+ QK E+ +Q LER N+
Sbjct: 1736 ARIAQLEEELEEEQGNMEAMSDRVRKATLQAEQLSNELATERSTAQKNESARQQLERQNK 1795
Query: 5368 DYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTT 5547
+ ++K+ E+E +++ ++ +AALEAK+ LE+Q+ E +EK AA ++ ++ +K+L +
Sbjct: 1796 ELRSKLQEVEGAVKAKLKSTVAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEVL 1855
Query: 5548 QQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANE 5727
Q EDE++ EQ KE EK N K + L+RQL+EAE+E R +QRE D+ ++NE
Sbjct: 1856 LQVEDERKMAEQYKEQAEKGNTKVKQLKRQLEEAEEESQCINANRRKLQRELDEATESNE 1915
Query: 5728 QLTREL 5745
+ RE+
Sbjct: 1916 AMGREV 1921
Score = 97.1 bits (240), Expect = 5e-18
Identities = 120/601 (19%), Positives = 233/601 (37%), Gaps = 39/601 (6%)
Frame = +1
Query: 4066 GLRAHLEKE-------IHAARQGA--GEARRKAEESVNQQLEELR--KKNLRDVEHLQKQ 4212
G+ AHLE+E + A Q G RKA QQL ++ ++N L+
Sbjct: 773 GVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFTKRQQQLTAMKVIQRNCAAYLKLRNW 832
Query: 4213 LEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFE---SQMAEERVAV 4383
K + L + ++E++ E++ + + +E K+ E +Q+AEE+ +
Sbjct: 833 QWWRLFTKVKPLLQVTRQEEEMQAKEEEMQKITERQQKAETELKELEQKHTQLAEEKTLL 892
Query: 4384 QKALLDRDAMSQELRDRETRVLSLLNEVDI----MKEHLEESDRVRRSLQQELQDSISNK 4551
Q+ L + E + R+ + E++ M+ LEE + R+ LQ E +
Sbjct: 893 QEQLQAETELYAESEEMRVRLAAKKQELEEILHEMEARLEEEEDRRQQLQAERKKMAQQM 952
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAI 4731
D + + E E A++ L+ E ++++LED++ + +D +L + L+
Sbjct: 953 LDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDDILVMDDQNSKLSKERKLLEERVSDLT 1012
Query: 4732 SNKDVEAEEKRRGLLK-------QIRDLENELENEKRGKSGAVSHRKKIEN--------- 4863
+N E EEK + L K I +LE L+ E++ + ++K+E
Sbjct: 1013 TNL-AEEEEKAKNLTKLKSKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQI 1071
Query: 4864 -----QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREAD 5028
QI EL+ QL + +EE + ++ R+ + I+ L + D
Sbjct: 1072 ADLQAQIAELKMQLA---KKEEELQAALARLDEEIAQKNNALKKIRELEGHISDLQEDLD 1128
Query: 5029 RKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXX 5208
+ A +Q R+ E L + + + KR E + +
Sbjct: 1129 SERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQ------ELRAKREQEVTVLKKA 1182
Query: 5209 XXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKIT 5388
++ +Q+ Q +E++T L + + KQ+LE+ N D
Sbjct: 1183 LDEETRSHEAQVQEMRQKHTQA-VEELTEQLEQFKRAKANLDKSKQTLEKENAD------ 1235
Query: 5389 ELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEK 5568
L +L V GQ K ++LE +L D + D +
Sbjct: 1236 -----------------------LAGELRVLGQAKQEVEHKKKKLEVQLQDLQSKCSDGE 1272
Query: 5569 RANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
RA + + + K + ++ L+EAE + + ++ + D + ++ TR+ +
Sbjct: 1273 RARAELSDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLGSQLQDTQELLQEETRQKL 1332
Query: 5749 N 5751
N
Sbjct: 1333 N 1333
>gi|19879404|gb|AAK85118.1| non-muscle myosin II heavy chain [Loligo
pealei]
Length = 1964
Score = 1739 bits (4505), Expect = 0.0
Identities = 908/1920 (47%), Positives = 1283/1920 (66%), Gaps = 5/1920 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
+L+YL V R + DP+ + WA R++ WVP + GF+ S+K E DEV+V++ DT ++
Sbjct: 15 ELKYLTVDRNILTDPSAQSQWAARRMVWVPSETHGFIGASVKEEKGDEVVVDVEDTGKRT 74
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
T RDD+QK NPPKF+K+EDM+ELT LNEASVLHNLKDRYYS LIYTYSGLFCVV+NPYK
Sbjct: 75 TFHRDDIQKMNPPKFNKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVVNPYK 134
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
+LPIY + +IE ++GKKRHE+PPH+FAI DTAYRSMLQ+REDQSILCTGESGAGKTENTK
Sbjct: 135 RLPIYQDKVIELYRGKKRHEVPPHVFAITDTAYRSMLQDREDQSILCTGESGAGKTENTK 194
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVIQYLA+VA ++R AA ++ V + GELE+QLLQANPILEAFGN+KT+K
Sbjct: 195 KVIQYLAYVAASSR-----AANNRSSVAS---FHGSGELENQLLQANPILEAFGNAKTIK 246
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
NDNSSRFGKF+RINFDMSGYI GANIE YLLEKSR +RQA+ ERSFHIFYQ L G S ++
Sbjct: 247 NDNSSRFGKFVRINFDMSGYICGANIETYLLEKSRSVRQAEGERSFHIFYQFLTGASTEQ 306
Query: 907 KSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLL 1086
K+++LLE +Y ++ + + + VDDV EF T +M +MG + D+++ I RVVSAVLL
Sbjct: 307 KNDFLLEDAKSYHYMSSGPMPVNGVDDVAEFKQTHEAMLVMGLSSDDVNGIFRVVSAVLL 366
Query: 1087 LGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQE 1266
GN+ F QE+ SDQA L D+ V QKVCHLLGL V L +AFLRP+IKVGR+ V KAQ +E
Sbjct: 367 FGNMVFRQERNSDQATLPDNTVAQKVCHLLGLNVTALTQAFLRPKIKVGRDHVTKAQTKE 426
Query: 1267 QAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQIC 1446
QAE++VEAI+KA YER+FKWLV RINKSLDRT RQGAS GILDIAGFEIF +NSFEQ+C
Sbjct: 427 QAEYSVEAISKACYERMFKWLVIRINKSLDRTKRQGAS--GILDIAGFEIFKMNSFEQLC 484
Query: 1447 INYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEE 1626
INYTNEKLQQLFN+TMFILEQEEYQREG+EW FIDFGLDLQPTIDLIEKPMG+LALLDEE
Sbjct: 485 INYTNEKLQQLFNHTMFILEQEEYQREGMEWKFIDFGLDLQPTIDLIEKPMGILALLDEE 544
Query: 1627 CLFPKANDKSFVEKLQKTHNKHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMDPL 1806
C FPKA DK++V+KL H PKF PD R+ + F+++HYAGRVDYSA WLMKNMDPL
Sbjct: 545 CWFPKATDKTYVDKLLGHHVNRPKFEKPDFRADADFSLIHYAGRVDYSAQAWLMKNMDPL 604
Query: 1807 NENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTK 1986
NENVV L+QNS+DPF+ IWKDAE G+ AA ETAFG R+RKGMFRTVSQL+KEQL K
Sbjct: 605 NENVVALLQNSSDPFIQLIWKDAEIVGLGAAAAAETAFGSRTRKGMFRTVSQLYKEQLAK 664
Query: 1987 LMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQE 2166
LM TLRNT+P+FVRCIIPNH+K+ GKI + LVL+QLRCNGVLEGIRICRQGFPNR+ FQE
Sbjct: 665 LMATLRNTNPNFVRCIIPNHDKRPGKIEAPLVLDQLRCNGVLEGIRICRQGFPNRILFQE 724
Query: 2167 FRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERD 2346
FR RYEILTP IPK F+DGK++V KMI +L++D NLYRIGQSK+FFR GVLAHLEEERD
Sbjct: 725 FRQRYEILTPSAIPKGFMDGKKAVGKMIESLELDPNLYRIGQSKIFFRAGVLAHLEEERD 784
Query: 2347 LKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKP 2526
LKLT +I+ FQA RG L+RR Y N AYLKLRNWQWWRLFTKVKP
Sbjct: 785 LKLTDIIIQFQAYVRGMLARRNYHKRLQQLSAIRVIQRNCSAYLKLRNWQWWRLFTKVKP 844
Query: 2527 LLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENS 2706
LL VT ++++ AK++EL+ KE K + ++ + E+K ++ E++++ EQLQ E+E
Sbjct: 845 LLSVTNQEEKLNAKEEELKKIKEHYEKTKFEYEDLERKFANLVDEKSLLAEQLQAETELC 904
Query: 2707 AELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXX 2886
E ++ R L R ELE ++N+ RL + K T+ D
Sbjct: 905 TEAEETRILLNNRKIELEEVLNETEARLEEEMRNSEFLHDEKNKLRLTIEDLEEQLEEEE 964
Query: 2887 XXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAK 3066
+K +VDQ D+ + LT++L+ E++ K
Sbjct: 965 QARQKLQMEKLSVDQRVKKLEEDIAVNTDSGNKLSKEKKYLEEKIHELTSKLVGEEDKFK 1024
Query: 3067 HGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNN 3246
K K R E+ L +LE + RE Q + ELE+ KRKL A+L D +D L EK +VEE+ +
Sbjct: 1025 QLGKQKSRAESALADLETQVQRETQNRQELEKVKRKLEADLADHRDQLNEKRAQVEEVQS 1084
Query: 3247 QLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRRE 3426
QL +R+EELQ L + ++ES KQ+R++Q+ I EL ED++ E+ +R KAE +R+
Sbjct: 1085 QLARREEELQSALQKSEDESVAKGTTLKQLRELQSQIQELSEDLDAEKQSREKAEKQKRD 1144
Query: 3427 VVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSR 3606
+ +LE +K ++ D +D +Q+L ++++ EV+ K+AIE+ Q E + E + K+++
Sbjct: 1145 LNEELEALKSELEDSLDTTAAVQELRNKRELEVDNLKKAIEENQKQGENQALELRQKYTK 1204
Query: 3607 QVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME 3786
Q+E +++ ++ KK ++ +EK + E AD+A ++ +Q ++ + ++KRK E+HL E
Sbjct: 1205 QLEAVNEDLDVIKKSKASIEKVKESLQAENADLANDLKQMQQAKQESERKRKQLESHLQE 1264
Query: 3787 IQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXX 3966
L + + +K L ++L + + E + E+ + + + R+++
Sbjct: 1265 QSMKLVDVERNKSELGEKLTKMQTEYEQAVASLEDSDASVLELNRKVSNLQTDLATATEG 1324
Query: 3967 XXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAE-- 4140
RLK+ ++ R +E+ +L D+ EE E + L+K++ + E ++ AE
Sbjct: 1325 LEEENRLKMQALSDLRTATEERESLHDKLEEEEENKKLLQKQLEKNQSLMVELKKNAETA 1384
Query: 4141 ESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASH 4320
ES EE KK LR +E L++Q+ + + R+ ++KKK+ +E ED +EL+ A
Sbjct: 1385 ESSRDNAEEELKKALRLIEQLRQQIADLQEQIARLEKAKKKLSEENEDFRVELDQQIAQV 1444
Query: 4321 RDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESD 4500
+ ++Q KF+ ++AEE+ ++ + + +E+ ++ T++++++NE++ +E EE +
Sbjct: 1445 NELTRKQAKFDQKLAEEKAISERLSAENEKSQREINEKSTKIMNIMNELEEEREKSEEME 1504
Query: 4501 RVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARL 4680
+ + EL+ +S+ D ++V +LE+ K+ LE+++ + + E E++LQ E ++L
Sbjct: 1505 KKWKKSHNELEGLVSSVDSDKRSVLDLERQKKQLESQVQEQLGLILESEEDLQKMESSKL 1564
Query: 4681 RLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIE 4860
R EV QA+ S+ + +S +D A+E +RGL +Q+++LE E+E+ + K+ AV +KK+E
Sbjct: 1565 RNEVNLQAIISKLQKELSGRDENADEIKRGLQRQLKELEAEVEDARTQKTAAVHGKKKLE 1624
Query: 4861 NQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFR 5040
+ + +L +QL + KE+ EYQ E EEAR A+ D ++ +K +
Sbjct: 1625 HDLNQLSEQLIAVTKQKEDAVKQARKANSQMKEYQRETEEARAAQHDANTAFKDMKKKVK 1684
Query: 5041 AVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISS---EEKRRLEAKIAQXXX 5211
++E E ++E +ARK A G S EEKRRLE +I++
Sbjct: 1685 SLEDELVVMQEDVAAAERARKNAETERDELQEEIANGTVSKSSLNEEKRRLELRISELED 1744
Query: 5212 XXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITE 5391
Q+N E+ IDK +K EQ+ T+L+ E++ +Q E ++ SLER N+D KAK+ E
Sbjct: 1745 LLDEEQNNSEILIDKNKKVNAHYEQLLTELNAEKSTSQTLENQRLSLERQNKDLKAKVQE 1804
Query: 5392 LESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKR 5571
LE+ A+ + + +AALE K+ LEDQL+ + +EK A R R+L+K++ + Q E+E+R
Sbjct: 1805 LENQAKIKQKTMIAALEGKIANLEDQLDQDNKEKNTAMRVNRKLDKKIKELMLQVEEERR 1864
Query: 5572 ANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
+Q KE ++KS+ + + L+RQLDEAE+E++R T+ R +QR+ D+ ++ N+ ++RE+ N
Sbjct: 1865 HADQYKEQMDKSSARVKALKRQLDEAEEEVTRLNTQRRKLQRDLDEQMEQNQIVSREMSN 1924
>gi|111999|pir||S21801 myosin heavy chain, neuronal [similarity] - rat
Length = 1999
Score = 1691 bits (4380), Expect = 0.0
Identities = 894/1929 (46%), Positives = 1273/1929 (65%), Gaps = 18/1929 (0%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL V + + +P T A WA +KL WVP + GF S+K E DE +VEL + ++V +
Sbjct: 8 KYLYVDKNIINNPLTQADWAAKKLVWVPSEKSGFEAASLKEEVGDEAIVELAENGKKVKV 67
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDM+ELT LNEASVLHNLK+RYYS LIYTYSGLFCVVINPYK L
Sbjct: 68 NKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNL 127
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYSE+++E +KGKKRHEMPPHI+AI DTAYRSM+Q+REDQSILCTGESGAGKTENTKKV
Sbjct: 128 PIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKV 187
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
IQYLAHVA + ++K GELE QLLQANPILEAFGN+KTVKND
Sbjct: 188 IQYLAHVASSHKSKKDQ-----------------GELERQLLQANPILEAFGNAKTVKND 230
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA++ER+FHIFY +L G K+
Sbjct: 231 NSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKT 290
Query: 913 EYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 1092
+ LLE YRFL N +T+P D F T+ +MRIMG D+E +++V+S VL LG
Sbjct: 291 DLLLEPYGKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPDEEQIGLLKVISGVLQLG 350
Query: 1093 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA 1272
N+ F +E+ +DQA + D+ QKV HLLG+ V + + L PRIKVGR++V KAQ +EQA
Sbjct: 351 NIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQA 410
Query: 1273 EFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICIN 1452
+FA+EA+AKA+YE++F+WLV RINK+LD+T RQGASFIGILDIAGFEIF++NSFEQ+CIN
Sbjct: 411 DFAIEALAKATYEQMFRWLVMRINKALDKTKRQGASFIGILDIAGFEIFELNSFEQLCIN 470
Query: 1453 YTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDE 1623
YTNEKLQQLFN+TMFI EQEEYQREGIEW+FIDFGLDLQP IDLIE+P GVLALLDE
Sbjct: 471 YTNEKLQQLFNHTMFI-EQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDE 529
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMD 1800
EC FPKA DK+FVEKL + H KF P ++ K+ F ++HYAG+VDY D+WLMKNMD
Sbjct: 530 ECWFPKATDKTFVEKLVQEQGTHSKFQKPRQLKDKADFCIIHYAGKVDYKGDEWLMKNMD 589
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAFG--MRSRKGMFRTVSQLH 1968
PLN+NV L+ S+D FVA +WKD + G+ + ETAFG +++KGMFRTV QL+
Sbjct: 590 PLNDNVATLLHQSSDKFVAELWKDVDRIVGLDQVTGITETAFGSAYKTKKGMFRTVGQLY 649
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
KE LTKLM TLRNT+P+FVRCIIPNHEK++GK++ +LVL+QLRCNGVLEGIRICRQGFPN
Sbjct: 650 KESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPN 709
Query: 2149 RVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAH 2328
R+ FQEFR RYEILTP+ IPK F+DGK++ +MI AL++D NLYRIGQSK+FFR GVLAH
Sbjct: 710 RIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAH 769
Query: 2329 LEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRL 2508
LEEERDLK+T +I+ FQA CRG+L+R+ + N AYLKLR+WQWWR+
Sbjct: 770 LEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKILQRNCAAYLKLRHWQWWRV 829
Query: 2509 FTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQ 2688
FTKVKPLLQVTR ++E++AKD+EL E+ K+E + E E+K Q++ E+ ++ EQLQ
Sbjct: 830 FTKVKPLLQVTRQEEELQAKDEELMKKVEKQTKVEAELEEMERKHQQLLEEKNILAEQLQ 889
Query: 2689 QESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXX 2868
E+E AE +++R RL + QELE I++D+ R+ ++K+ D
Sbjct: 890 AETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKEQGHKNDLEE 949
Query: 2869 XXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLD 3048
+K + +D TT L +
Sbjct: 950 QLDEMESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTE 1009
Query: 3049 HEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGK 3228
EE++K K K + E + +LE+ L RE + + ELE+ +RKL + D D +AE +
Sbjct: 1010 EEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQ 1069
Query: 3229 VEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKA 3408
+ EL QL K++EELQ L R +EE+A + K++R++++ I EL+ED+E+ER +RNKA
Sbjct: 1070 IAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKA 1129
Query: 3409 EMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQ 3588
E +R++ +LE +K ++ D D Q+L S++++EVN K+ +E+ T E +I+E
Sbjct: 1130 EKQKRDLGEELEALKTELEDLTDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEM 1189
Query: 3589 KAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIH 3768
+ K S+ VEEL +Q+EQ K++ + LEK + + ER ++A E+ +L D + KRK
Sbjct: 1190 RQKHSQAVEELAEQLEQTKRKVANLEKAKQTLENERGELANEVKVLLQGGRDSEHKRKKV 1249
Query: 3769 EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXX 3948
EA L E+Q E + L D++ + + ELD++ + + + + + + +
Sbjct: 1250 EAQLQELQVKFNEGERRVTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQL 1309
Query: 3949 XXXXXXXXXXTRLKIANINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHAARQGAGEA 4125
R K++ + +Q+EDEKN+ ++ +EE E + +LEK+I +
Sbjct: 1310 QDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEEAKHNLEKQIATLHAQVADM 1369
Query: 4126 RRKAEESVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMEL 4299
++K E+SV + EE+++K +D+E L ++ EE A +++ ++K ++QQEL+D ++L
Sbjct: 1370 KKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDL 1429
Query: 4300 ENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLN-EVDIM 4476
++ R S + EK+QKKF+ +AEE K +R ++E ++ T+ LSL E++ M
Sbjct: 1430 DHQRQSACNLEKKQKKFDQLLAEEITKSAKYAEERARDAEERAEKATKELSLARAELEAM 1489
Query: 4477 KEHLEESDRVRRSLQQ--ELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELED 4650
+ ++++ +R++LQ+ E D +S+K D K+V E EK+K E ++ + + Q+ E ED
Sbjct: 1490 E---QKAEFLRKNLQEMTERLDEMSSKVDDAKSVLEHEKSKLGREQQVMEEKTQLLEEED 1546
Query: 4651 NLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKS 4830
L EDA+LRLEV QA+K++ +R + + ++EEK++ L++Q+R++E ELE++++ S
Sbjct: 1547 ELAQTEDAKLRLEVNLQAMKAQFERDLQGRQDDSEEKQKKLVRQVREMEAELEDQRKEMS 1606
Query: 4831 GAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAA 5010
A + KK+E + +LE ++ AN+ ++E + E ++ R ++E+IA
Sbjct: 1607 RARAAVKKLEMDLKDLEAHIDSANKNRDEAKIQLRNLQAQMKDCMRELDDTRASREEIAL 1666
Query: 5011 LLREADRKFRAVEAEREQLRE----ANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKR 5178
+E ++K +++EAE QL+E A QA+++ K G++ EE R
Sbjct: 1667 QAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEISNASGK-AGLAKEELR 1725
Query: 5179 RLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLER 5358
RLEA+IAQ Q N EL D+ +KA +Q++QI DL++ER QK E +Q LER
Sbjct: 1726 RLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINADLNLERGHAQKNENARQQLER 1785
Query: 5359 SNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLN 5538
N++ K K+ E+E +S+ +A + ALEAK+ LE+QL+ E +E+ AA + RR EK+L
Sbjct: 1786 QNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLK 1845
Query: 5539 DTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLD 5718
D Q +DE+R EQ K+ +K++ + + L+RQL+EAE+E R R +QRE +D +
Sbjct: 1846 DVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATE 1905
Query: 5719 ANEQLTREL 5745
+ + RE+
Sbjct: 1906 TADAMNREV 1914
Score = 107 bits (268), Expect = 3e-21
Identities = 137/687 (19%), Positives = 275/687 (39%), Gaps = 50/687 (7%)
Frame = +1
Query: 2554 EIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGR 2733
+ A + +L+ T+E L + KL QV E+ +EQL++E E + +
Sbjct: 1301 DFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEEA------KHN 1354
Query: 2734 LQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXD 2913
L+ + L V DM+ ++ +RK + +
Sbjct: 1355 LEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKT 1414
Query: 2914 KTNVDQXXXXXXXXXXXX-QDAYDXXXXXXXXXXXXXXGLTT-------QLLDHEERAKH 3069
KT + Q Q A + +T + D EERA+
Sbjct: 1415 KTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEITKSAKYAEERARDAEERAEK 1474
Query: 3070 GVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSK---DHLAEKMGK---V 3231
K +L +EQ R+ E+ + ++ ++++D+K +H K+G+ V
Sbjct: 1475 ATKELSLARAELEAMEQKAEFLRKNLQEMTERLDEMSSKVDDAKSVLEHEKSKLGREQQV 1534
Query: 3232 EELNNQLMKRDEELQHQLT----------------------RYDEESANVTLMQKQMRDM 3345
E QL++ ++EL R D+ + +Q+R+M
Sbjct: 1535 MEEKTQLLEEEDELAQTEDAKLRLEVNLQAMKAQFERDLQGRQDDSEEKQKKLVRQVREM 1594
Query: 3346 QTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEV 3525
+ +++ R++M R A K EM +++ A ++ + + + LQ M E+
Sbjct: 1595 EAELEDQRKEMSRARAAVKKLEMDLKDLEAHIDSANKNRDEAKIQLRNLQAQMKDCMREL 1654
Query: 3526 NATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADM 3705
+ T+ + E+I ++ K E+K K + ++ Q +++ + E+ + QA QER ++
Sbjct: 1655 DDTRASREEI--ALQAKENEKKLK------SMEAEMIQLQEELAAAERAKRQAQQERDEL 1706
Query: 3706 AQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLN--- 3876
A EI+ ++ + EA + +++ L E + + D+L+++ ++D +N
Sbjct: 1707 ADEISNASGKAGLAKEELRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINADL 1766
Query: 3877 -----------RVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLE 4023
R++ E ++ +L KIA QLE
Sbjct: 1767 NLERGHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIA------QLE 1820
Query: 4024 DEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHL 4203
++ + E++ A EK++ + RR AE Q ++ K ++ L
Sbjct: 1821 EQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAE-----QYKDQADKASTRLKQL 1875
Query: 4204 QKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAV 4383
++QLEE+E +R S++K+Q+ELED++ E A +R+ + K + + V
Sbjct: 1876 KRQLEEAEEEAQRANASRRKLQRELEDAT---ETADAMNREVSSLKNKL--RRGDLPFVV 1930
Query: 4384 QKALLDRDAMSQELRDRETRVLSLLNE 4464
+ L+ + + D E++ SL+NE
Sbjct: 1931 TRRLVRKGTLELSDDDDESKA-SLINE 1956
>gi|14530418|emb|CAA99841.2| Hypothetical protein F20G4.3
[Caenorhabditis elegans]
gi|14530566|emb|CAA99931.2| Hypothetical protein F20G4.3
[Caenorhabditis elegans]
Length = 2003
Score = 1649 bits (4270), Expect = 0.0
Identities = 865/1914 (45%), Positives = 1264/1914 (65%), Gaps = 14/1914 (0%)
Frame = +1
Query: 46 DPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDE--VLVELVDTSRQVTISRDDVQKAN 219
+P+ A WA++KL WVP + +GF +G++ E + + + +EL++T + +S DD QK N
Sbjct: 22 NPSISADWAKKKLMWVPSEKDGFALGAVIGEPHADGTIDIELMETGERQRVSSDDCQKPN 81
Query: 220 PPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIE 399
PPK+DK EDMS LT LNEASVLHNLK RY+S+L YTYSGLFCVVINPYK++PIY++ + E
Sbjct: 82 PPKYDKCEDMSMLTCLNEASVLHNLKQRYFSNLYYTYSGLFCVVINPYKRIPIYTDTIAE 141
Query: 400 EFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAG 579
+FK KKR EMPPHIFA+AD AYRSMLQER+DQSILCTGESGAGKTENTKKVIQYLA+VA
Sbjct: 142 QFKCKKRKEMPPHIFAVADEAYRSMLQERDDQSILCTGESGAGKTENTKKVIQYLAYVA- 200
Query: 580 ATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFI 759
N+S+ + ++ +G+LE QLLQANPILEAFGNSKTVKNDNSSRFGKFI
Sbjct: 201 ---NRSMVKNRKTSVDLDTSTNRIMGQLEEQLLQANPILEAFGNSKTVKNDNSSRFGKFI 257
Query: 760 RINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLE-GVD 936
R++FD +G ISGANIEFYLLEKSRVL+QA +ERSFHIFYQ+L+G S ++ YLLE +
Sbjct: 258 RVHFDSTGCISGANIEFYLLEKSRVLKQAPNERSFHIFYQLLKGLSKVQREHYLLEDSLS 317
Query: 937 NYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEK 1116
Y+F+ N L VDD E T+N+M IMG D+EI I+RVVSAV+L GNLEF+ E
Sbjct: 318 KYKFVSNGDSKLAGVDDGAEMKETLNAMSIMGLNDEEIGGILRVVSAVMLFGNLEFSHEN 377
Query: 1117 KS-DQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAI 1293
K+ DQA+L +D V QK+ LLG+ V EL +AFL+P+IKV R+ V++AQ+ +Q F+V AI
Sbjct: 378 KNNDQAVLLNDAVAQKIASLLGVNVTELMRAFLKPKIKVQRDLVHRAQSVDQVNFSVGAI 437
Query: 1294 AKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQ 1473
AKASYERLF+WLV R+NKSLDRT +Q SFIGILDIAGFEIF+ NSFEQ+CINYTNEKLQ
Sbjct: 438 AKASYERLFRWLVHRLNKSLDRTRQQSVSFIGILDIAGFEIFETNSFEQLCINYTNEKLQ 497
Query: 1474 QLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDK 1653
QLFNNTMF+ EQ+EY EG+EW F+DFGL+LQPTIDLI+KPMG+++ LD+ CLFP+ ND+
Sbjct: 498 QLFNNTMFVREQQEYLDEGLEWKFLDFGLNLQPTIDLIDKPMGIMSTLDDVCLFPQGNDQ 557
Query: 1654 SFVEKLQKTHNKHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQ 1833
SFV++L TH++HPK++VP++RS+S FAVVHYAGRVDY ++ W +KNMDPLNENV+ +++
Sbjct: 558 SFVQRLNNTHSQHPKYVVPEIRSRSDFAVVHYAGRVDYQSEGWRVKNMDPLNENVIDVLK 617
Query: 1834 NSTDPFVAGIWKD-AEFAGICAAEMNETA--FGMR-SRKGMFRTVSQLHKEQLTKLMTTL 2001
S + + +WKD A+ + AA+ FG R +KGMFRTVSQL+KEQL +LM+TL
Sbjct: 618 TSKESLIVDMWKDIADVCSLSAADSTSDTGVFGSRVPKKGMFRTVSQLYKEQLARLMSTL 677
Query: 2002 RNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRY 2181
NT+PHFVRCIIPNHEKK G +N++LVL+QLRCNGVLEGIRICRQGFP R+PFQEFR RY
Sbjct: 678 NNTNPHFVRCIIPNHEKKHGVLNAHLVLDQLRCNGVLEGIRICRQGFPTRLPFQEFRQRY 737
Query: 2182 E-ILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLT 2358
E +L PDV P F+DGK +V +++ L++D NL+RIGQSK+FFR+GV+A EE RD KL+
Sbjct: 738 EKLLAPDVNPAGFMDGKNAVYRIVQYLEVDANLFRIGQSKIFFRSGVIAEFEEMRDQKLS 797
Query: 2359 ALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQV 2538
ALI +FQAQCRG+L RR+ NGLA+++LR WQWWRL TKVKPLL+V
Sbjct: 798 ALIESFQAQCRGWLGRRVMVRRREQEVAIKILQRNGLAWMRLREWQWWRLLTKVKPLLEV 857
Query: 2539 TRTDDEIRAKDDELRATKERLLKME---HDFRENEKKLDQVIVERAVIQEQLQQESENSA 2709
T D+ I ++ EL+ T E+L + E D+++ +K+D+ ER V++ +L ES A
Sbjct: 858 TNKDELIAEREQELKVTAEKLRRSEVFISDYKQQMEKMDE---ERLVLKTRLDAESSERA 914
Query: 2710 ELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXX 2889
E+ + R R+ R ELE I+ ++ RL RK E VR
Sbjct: 915 EIFEERSRMAARRDELEGILEEVSKRLEIEEQKAKKADSESRKLTEMVRHLEENLEDEER 974
Query: 2890 XXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKH 3069
+K +++ +D+ + L+++L+D ER+K
Sbjct: 975 SRQKLLLEKNSIESRLKELEAQGLELEDSGNKLSKEKKALEERCEDLSSRLIDEVERSKQ 1034
Query: 3070 GVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQ 3249
VKAK RLE + E+ +L +E+Q + E +R +L + ++ EK K EEL NQ
Sbjct: 1035 LVKAKARLEATVAEINDELEKEKQQRHNAETARRAAETQLREEQESCLEKTRKAEELTNQ 1094
Query: 3250 LMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREV 3429
LM+++ EL R DEE A +++++R+++ +D+ E+ E+ AR KAE RR++
Sbjct: 1095 LMRKESELSQISIRNDEELAARQQLEREIREIRAQLDDAIEETNKEKAARQKAEKARRDM 1154
Query: 3430 VAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQ 3609
+LE K ++ + D+ + L +++DEE ++ +E+ + E +EE KA+ ++
Sbjct: 1155 AEELESYKQELEESNDKTVLHSQLKAKRDEEYAHLQKQLEETVKSSEEVVEEMKAQNQKK 1214
Query: 3610 VEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEI 3789
+EEL++ I+Q K+Q+ +K ++ A+ + + E++ + ++R + +KKRK E LME
Sbjct: 1215 IEELNETIDQLKRQKISADKAKSSAESDNENFRAELSNIASARLEAEKKRKAAETSLMEK 1274
Query: 3790 QANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXX 3969
+ E + L+ +L + +EL+ + + + +E +N+ ++ A+
Sbjct: 1275 DHKMREMQSNLDDLMAKLSKMNNELESIQKAKSADETLNSNLLKKNASLDMQLSELTEAS 1334
Query: 3970 XXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESV 4149
R + N+ RQLE++ ++ +++A + +EKE+ + EAR+K +E
Sbjct: 1335 EEDRRTRATLNNKIRQLEEDLAVAVEARDDALDAQEKIEKEVKEVKSLLAEARKKLDEEN 1394
Query: 4150 NQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDS 4329
+ +EELRKK +++ +++ + +E A+++ ++KKK QE ED EL +V A+ R+
Sbjct: 1395 REVMEELRKKKEKELSAEKERADMAEQARDKAERAKKKAIQEAEDVQKELTDVVAATREM 1454
Query: 4330 EKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVR 4509
E++ +KF+ Q+AEER A +RD Q LRD ET+ L L NE+ K+ +++ ++ +
Sbjct: 1455 ERKMRKFDQQLAEERNNTLLAQQERDMAHQMLRDAETKALVLSNELSEKKDIVDQLEKDK 1514
Query: 4510 RSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLE 4689
R+L+ E+ + S KDD GKNV+ELEK KR L+ EL+ Q+ ELED LQ+A+DAR R+E
Sbjct: 1515 RTLKLEIDNLASTKDDAGKNVYELEKTKRRLDEELSRAEQQIIELEDALQLADDARSRVE 1574
Query: 4690 VTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQI 4869
V QA++SE +R +++++ + +++++GL +IR+L ELE+E+R + A++++KKIE+QI
Sbjct: 1575 VNMQAMRSEFERQLASREEDEDDRKKGLTSKIRNLTEELESEQRARQAAIANKKKIESQI 1634
Query: 4870 GELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVE 5049
EL ++ E + R E+ + Q++ EAR A ED A R+A+++ RA E
Sbjct: 1635 SELTEKNEASLRQIEDLSRQLRKAQLGWKDLQLDVTEARAAMEDALAGQRDAEKRARASE 1694
Query: 5050 AEREQLREANEGLMQARK--QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXX 5223
E ++L + + +++ + + S+EEKRRLEAK+
Sbjct: 1695 DEIKRLTADIQAVSSSKRKAEAERDELIEEVSSLRASSFSNEEKRRLEAKVIDLEDQLDE 1754
Query: 5224 XQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESG 5403
S ELA +K RK+Q QLEQ+T DL+MER++ ++TE++K +LER+NRD K ++ + E+
Sbjct: 1755 EASANELAQEKVRKSQQQLEQMTADLAMERSVCERTESDKIALERANRDLKQQLQDAENT 1814
Query: 5404 AQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQ 5583
A +R R Q+ EAKV LE QL++E Q+K R RR+E ++ + Q E+EKR E
Sbjct: 1815 AVARLRTQINVAEAKVSSLEQQLSLEEQDKMRQGRTLRRMETKMAEMQQMLEEEKRQGES 1874
Query: 5584 AKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
++ +++ N + R LR QL++ E E R K ++ +R A+++ D NE L+R++
Sbjct: 1875 NRQAVDRQNARIRQLRTQLEDTEAERDRLTNKLKDERRRAEEMTDLNETLSRDV 1928
Score = 44.3 bits (103), Expect = 0.036
Identities = 37/163 (22%), Positives = 69/163 (41%), Gaps = 6/163 (3%)
Frame = +1
Query: 5278 LEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQ------SRARAQMAAL 5439
LE+++ L +E +K ++E + L R + + + E Q + +++ L
Sbjct: 934 LEEVSKRLEIEEQKAKKADSESRKLTEMVRHLEENLEDEERSRQKLLLEKNSIESRLKEL 993
Query: 5440 EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKN 5619
EA+ LED N +EK A L RL D ++ + +A + + + + N +
Sbjct: 994 EAQGLELEDSGNKLSKEKKALEERCEDLSSRLIDEVERSKQLVKAKARLEATVAEINDEL 1053
Query: 5620 RNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
++Q AE T+ R Q + E+LT +LM
Sbjct: 1054 EKEKQQRHNAETARRAAETQLREEQESCLEKTRKAEELTNQLM 1096
>gi|7499530|pir||T21174 hypothetical protein F20G4.3 - Caenorhabditis
elegans
Length = 2020
Score = 1649 bits (4270), Expect = 0.0
Identities = 865/1914 (45%), Positives = 1264/1914 (65%), Gaps = 14/1914 (0%)
Frame = +1
Query: 46 DPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDE--VLVELVDTSRQVTISRDDVQKAN 219
+P+ A WA++KL WVP + +GF +G++ E + + + +EL++T + +S DD QK N
Sbjct: 39 NPSISADWAKKKLMWVPSEKDGFALGAVIGEPHADGTIDIELMETGERQRVSSDDCQKPN 98
Query: 220 PPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIE 399
PPK+DK EDMS LT LNEASVLHNLK RY+S+L YTYSGLFCVVINPYK++PIY++ + E
Sbjct: 99 PPKYDKCEDMSMLTCLNEASVLHNLKQRYFSNLYYTYSGLFCVVINPYKRIPIYTDTIAE 158
Query: 400 EFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAG 579
+FK KKR EMPPHIFA+AD AYRSMLQER+DQSILCTGESGAGKTENTKKVIQYLA+VA
Sbjct: 159 QFKCKKRKEMPPHIFAVADEAYRSMLQERDDQSILCTGESGAGKTENTKKVIQYLAYVA- 217
Query: 580 ATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFI 759
N+S+ + ++ +G+LE QLLQANPILEAFGNSKTVKNDNSSRFGKFI
Sbjct: 218 ---NRSMVKNRKTSVDLDTSTNRIMGQLEEQLLQANPILEAFGNSKTVKNDNSSRFGKFI 274
Query: 760 RINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLE-GVD 936
R++FD +G ISGANIEFYLLEKSRVL+QA +ERSFHIFYQ+L+G S ++ YLLE +
Sbjct: 275 RVHFDSTGCISGANIEFYLLEKSRVLKQAPNERSFHIFYQLLKGLSKVQREHYLLEDSLS 334
Query: 937 NYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEK 1116
Y+F+ N L VDD E T+N+M IMG D+EI I+RVVSAV+L GNLEF+ E
Sbjct: 335 KYKFVSNGDSKLAGVDDGAEMKETLNAMSIMGLNDEEIGGILRVVSAVMLFGNLEFSHEN 394
Query: 1117 KS-DQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAI 1293
K+ DQA+L +D V QK+ LLG+ V EL +AFL+P+IKV R+ V++AQ+ +Q F+V AI
Sbjct: 395 KNNDQAVLLNDAVAQKIASLLGVNVTELMRAFLKPKIKVQRDLVHRAQSVDQVNFSVGAI 454
Query: 1294 AKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQ 1473
AKASYERLF+WLV R+NKSLDRT +Q SFIGILDIAGFEIF+ NSFEQ+CINYTNEKLQ
Sbjct: 455 AKASYERLFRWLVHRLNKSLDRTRQQSVSFIGILDIAGFEIFETNSFEQLCINYTNEKLQ 514
Query: 1474 QLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDK 1653
QLFNNTMF+ EQ+EY EG+EW F+DFGL+LQPTIDLI+KPMG+++ LD+ CLFP+ ND+
Sbjct: 515 QLFNNTMFVREQQEYLDEGLEWKFLDFGLNLQPTIDLIDKPMGIMSTLDDVCLFPQGNDQ 574
Query: 1654 SFVEKLQKTHNKHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQ 1833
SFV++L TH++HPK++VP++RS+S FAVVHYAGRVDY ++ W +KNMDPLNENV+ +++
Sbjct: 575 SFVQRLNNTHSQHPKYVVPEIRSRSDFAVVHYAGRVDYQSEGWRVKNMDPLNENVIDVLK 634
Query: 1834 NSTDPFVAGIWKD-AEFAGICAAEMNETA--FGMR-SRKGMFRTVSQLHKEQLTKLMTTL 2001
S + + +WKD A+ + AA+ FG R +KGMFRTVSQL+KEQL +LM+TL
Sbjct: 635 TSKESLIVDMWKDIADVCSLSAADSTSDTGVFGSRVPKKGMFRTVSQLYKEQLARLMSTL 694
Query: 2002 RNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRY 2181
NT+PHFVRCIIPNHEKK G +N++LVL+QLRCNGVLEGIRICRQGFP R+PFQEFR RY
Sbjct: 695 NNTNPHFVRCIIPNHEKKHGVLNAHLVLDQLRCNGVLEGIRICRQGFPTRLPFQEFRQRY 754
Query: 2182 E-ILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLT 2358
E +L PDV P F+DGK +V +++ L++D NL+RIGQSK+FFR+GV+A EE RD KL+
Sbjct: 755 EKLLAPDVNPAGFMDGKNAVYRIVQYLEVDANLFRIGQSKIFFRSGVIAEFEEMRDQKLS 814
Query: 2359 ALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQV 2538
ALI +FQAQCRG+L RR+ NGLA+++LR WQWWRL TKVKPLL+V
Sbjct: 815 ALIESFQAQCRGWLGRRVMVRRREQEVAIKILQRNGLAWMRLREWQWWRLLTKVKPLLEV 874
Query: 2539 TRTDDEIRAKDDELRATKERLLKME---HDFRENEKKLDQVIVERAVIQEQLQQESENSA 2709
T D+ I ++ EL+ T E+L + E D+++ +K+D+ ER V++ +L ES A
Sbjct: 875 TNKDELIAEREQELKVTAEKLRRSEVFISDYKQQMEKMDE---ERLVLKTRLDAESSERA 931
Query: 2710 ELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXX 2889
E+ + R R+ R ELE I+ ++ RL RK E VR
Sbjct: 932 EIFEERSRMAARRDELEGILEEVSKRLEIEEQKAKKADSESRKLTEMVRHLEENLEDEER 991
Query: 2890 XXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKH 3069
+K +++ +D+ + L+++L+D ER+K
Sbjct: 992 SRQKLLLEKNSIESRLKELEAQGLELEDSGNKLSKEKKALEERCEDLSSRLIDEVERSKQ 1051
Query: 3070 GVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQ 3249
VKAK RLE + E+ +L +E+Q + E +R +L + ++ EK K EEL NQ
Sbjct: 1052 LVKAKARLEATVAEINDELEKEKQQRHNAETARRAAETQLREEQESCLEKTRKAEELTNQ 1111
Query: 3250 LMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREV 3429
LM+++ EL R DEE A +++++R+++ +D+ E+ E+ AR KAE RR++
Sbjct: 1112 LMRKESELSQISIRNDEELAARQQLEREIREIRAQLDDAIEETNKEKAARQKAEKARRDM 1171
Query: 3430 VAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQ 3609
+LE K ++ + D+ + L +++DEE ++ +E+ + E +EE KA+ ++
Sbjct: 1172 AEELESYKQELEESNDKTVLHSQLKAKRDEEYAHLQKQLEETVKSSEEVVEEMKAQNQKK 1231
Query: 3610 VEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEI 3789
+EEL++ I+Q K+Q+ +K ++ A+ + + E++ + ++R + +KKRK E LME
Sbjct: 1232 IEELNETIDQLKRQKISADKAKSSAESDNENFRAELSNIASARLEAEKKRKAAETSLMEK 1291
Query: 3790 QANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXX 3969
+ E + L+ +L + +EL+ + + + +E +N+ ++ A+
Sbjct: 1292 DHKMREMQSNLDDLMAKLSKMNNELESIQKAKSADETLNSNLLKKNASLDMQLSELTEAS 1351
Query: 3970 XXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESV 4149
R + N+ RQLE++ ++ +++A + +EKE+ + EAR+K +E
Sbjct: 1352 EEDRRTRATLNNKIRQLEEDLAVAVEARDDALDAQEKIEKEVKEVKSLLAEARKKLDEEN 1411
Query: 4150 NQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDS 4329
+ +EELRKK +++ +++ + +E A+++ ++KKK QE ED EL +V A+ R+
Sbjct: 1412 REVMEELRKKKEKELSAEKERADMAEQARDKAERAKKKAIQEAEDVQKELTDVVAATREM 1471
Query: 4330 EKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVR 4509
E++ +KF+ Q+AEER A +RD Q LRD ET+ L L NE+ K+ +++ ++ +
Sbjct: 1472 ERKMRKFDQQLAEERNNTLLAQQERDMAHQMLRDAETKALVLSNELSEKKDIVDQLEKDK 1531
Query: 4510 RSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLE 4689
R+L+ E+ + S KDD GKNV+ELEK KR L+ EL+ Q+ ELED LQ+A+DAR R+E
Sbjct: 1532 RTLKLEIDNLASTKDDAGKNVYELEKTKRRLDEELSRAEQQIIELEDALQLADDARSRVE 1591
Query: 4690 VTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQI 4869
V QA++SE +R +++++ + +++++GL +IR+L ELE+E+R + A++++KKIE+QI
Sbjct: 1592 VNMQAMRSEFERQLASREEDEDDRKKGLTSKIRNLTEELESEQRARQAAIANKKKIESQI 1651
Query: 4870 GELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVE 5049
EL ++ E + R E+ + Q++ EAR A ED A R+A+++ RA E
Sbjct: 1652 SELTEKNEASLRQIEDLSRQLRKAQLGWKDLQLDVTEARAAMEDALAGQRDAEKRARASE 1711
Query: 5050 AEREQLREANEGLMQARK--QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXX 5223
E ++L + + +++ + + S+EEKRRLEAK+
Sbjct: 1712 DEIKRLTADIQAVSSSKRKAEAERDELIEEVSSLRASSFSNEEKRRLEAKVIDLEDQLDE 1771
Query: 5224 XQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESG 5403
S ELA +K RK+Q QLEQ+T DL+MER++ ++TE++K +LER+NRD K ++ + E+
Sbjct: 1772 EASANELAQEKVRKSQQQLEQMTADLAMERSVCERTESDKIALERANRDLKQQLQDAENT 1831
Query: 5404 AQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQ 5583
A +R R Q+ EAKV LE QL++E Q+K R RR+E ++ + Q E+EKR E
Sbjct: 1832 AVARLRTQINVAEAKVSSLEQQLSLEEQDKMRQGRTLRRMETKMAEMQQMLEEEKRQGES 1891
Query: 5584 AKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
++ +++ N + R LR QL++ E E R K ++ +R A+++ D NE L+R++
Sbjct: 1892 NRQAVDRQNARIRQLRTQLEDTEAERDRLTNKLKDERRRAEEMTDLNETLSRDV 1945
Score = 44.3 bits (103), Expect = 0.036
Identities = 37/163 (22%), Positives = 69/163 (41%), Gaps = 6/163 (3%)
Frame = +1
Query: 5278 LEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQ------SRARAQMAAL 5439
LE+++ L +E +K ++E + L R + + + E Q + +++ L
Sbjct: 951 LEEVSKRLEIEEQKAKKADSESRKLTEMVRHLEENLEDEERSRQKLLLEKNSIESRLKEL 1010
Query: 5440 EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKN 5619
EA+ LED N +EK A L RL D ++ + +A + + + + N +
Sbjct: 1011 EAQGLELEDSGNKLSKEKKALEERCEDLSSRLIDEVERSKQLVKAKARLEATVAEINDEL 1070
Query: 5620 RNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
++Q AE T+ R Q + E+LT +LM
Sbjct: 1071 EKEKQQRHNAETARRAAETQLREEQESCLEKTRKAEELTNQLM 1113
>gi|25150089|ref|NP_492186.2| non-muscle myosin, cytoplasmic, heavy
chain II, required for the establishment of embryonic
polarity; interacts with the serine threonine protein
kinase PAR-1 (231.3 kD) (nmy-2) [Caenorhabditis elegans]
Length = 2003
Score = 1649 bits (4270), Expect = 0.0
Identities = 865/1914 (45%), Positives = 1264/1914 (65%), Gaps = 14/1914 (0%)
Frame = +1
Query: 46 DPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDE--VLVELVDTSRQVTISRDDVQKAN 219
+P+ A WA++KL WVP + +GF +G++ E + + + +EL++T + +S DD QK N
Sbjct: 22 NPSISADWAKKKLMWVPSEKDGFALGAVIGEPHADGTIDIELMETGERQRVSSDDYQKPN 81
Query: 220 PPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIE 399
PPK+DK EDMS LT LNEASVLHNLK RY+S+L YTYSGLFCVVINPYK++PIY++ + E
Sbjct: 82 PPKYDKCEDMSMLTCLNEASVLHNLKQRYFSNLYYTYSGLFCVVINPYKRIPIYTDTIAE 141
Query: 400 EFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAG 579
+FK KKR EMPPHIFA+AD AYRSMLQER+DQSILCTGESGAGKTENTKKVIQYLA+VA
Sbjct: 142 QFKCKKRKEMPPHIFAVADEAYRSMLQERDDQSILCTGESGAGKTENTKKVIQYLAYVA- 200
Query: 580 ATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFI 759
N+S+ + ++ +G+LE QLLQANPILEAFGNSKTVKNDNSSRFGKFI
Sbjct: 201 ---NRSMVKNRKTSVDLDTSTNRIMGQLEEQLLQANPILEAFGNSKTVKNDNSSRFGKFI 257
Query: 760 RINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLE-GVD 936
R++FD +G ISGANIEFYLLEKSRVL+QA +ERSFHIFYQ+L+G S ++ YLLE +
Sbjct: 258 RVHFDSTGCISGANIEFYLLEKSRVLKQAPNERSFHIFYQLLKGLSKVQREHYLLEDSLS 317
Query: 937 NYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEK 1116
Y+F+ N L VDD E T+N+M IMG D+EI I+RVVSAV+L GNLEF+ E
Sbjct: 318 KYKFVSNGDSKLAGVDDGAEMKETLNAMSIMGLNDEEIGGILRVVSAVMLFGNLEFSHEN 377
Query: 1117 KS-DQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAI 1293
K+ DQA+L +D V QK+ LLG+ V EL +AFL+P+IKV R+ V++AQ+ +Q F+V AI
Sbjct: 378 KNNDQAVLLNDAVAQKIASLLGVNVTELMRAFLKPKIKVQRDLVHRAQSVDQVNFSVGAI 437
Query: 1294 AKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQ 1473
AKASYERLF+WLV R+NKSLDRT +Q SFIGILDIAGFEIF+ NSFEQ+CINYTNEKLQ
Sbjct: 438 AKASYERLFRWLVHRLNKSLDRTRQQSVSFIGILDIAGFEIFETNSFEQLCINYTNEKLQ 497
Query: 1474 QLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDK 1653
QLFNNTMF+ EQ+EY EG+EW F+DFGL+LQPTIDLI+KPMG+++ LD+ CLFP+ ND+
Sbjct: 498 QLFNNTMFVREQQEYLDEGLEWKFLDFGLNLQPTIDLIDKPMGIMSTLDDVCLFPQGNDQ 557
Query: 1654 SFVEKLQKTHNKHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQ 1833
SFV++L TH++HPK++VP++RS+S FAVVHYAGRVDY ++ W +KNMDPLNENV+ +++
Sbjct: 558 SFVQRLNNTHSQHPKYVVPEIRSRSDFAVVHYAGRVDYQSEGWRVKNMDPLNENVIDVLK 617
Query: 1834 NSTDPFVAGIWKD-AEFAGICAAEMNETA--FGMR-SRKGMFRTVSQLHKEQLTKLMTTL 2001
S + + +WKD A+ + AA+ FG R +KGMFRTVSQL+KEQL +LM+TL
Sbjct: 618 TSKESLIVDMWKDIADVCSLSAADSTSDTGVFGSRVPKKGMFRTVSQLYKEQLARLMSTL 677
Query: 2002 RNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRY 2181
NT+PHFVRCIIPNHEKK G +N++LVL+QLRCNGVLEGIRICRQGFP R+PFQEFR RY
Sbjct: 678 NNTNPHFVRCIIPNHEKKHGVLNAHLVLDQLRCNGVLEGIRICRQGFPTRLPFQEFRQRY 737
Query: 2182 E-ILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLT 2358
E +L PDV P F+DGK +V +++ L++D NL+RIGQSK+FFR+GV+A EE RD KL+
Sbjct: 738 EKLLAPDVNPAGFMDGKNAVYRIVQYLEVDANLFRIGQSKIFFRSGVIAEFEEMRDQKLS 797
Query: 2359 ALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQV 2538
ALI +FQAQCRG+L RR+ NGLA+++LR WQWWRL TKVKPLL+V
Sbjct: 798 ALIESFQAQCRGWLGRRVMVRRREQEVAIKILQRNGLAWMRLREWQWWRLLTKVKPLLEV 857
Query: 2539 TRTDDEIRAKDDELRATKERLLKME---HDFRENEKKLDQVIVERAVIQEQLQQESENSA 2709
T D+ I ++ EL+ T E+L + E D+++ +K+D+ ER V++ +L ES A
Sbjct: 858 TNKDELIAEREQELKVTAEKLRRSEVFISDYKQQMEKMDE---ERLVLKTRLDAESSERA 914
Query: 2710 ELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXX 2889
E+ + R R+ R ELE I+ ++ RL RK E VR
Sbjct: 915 EIFEERSRMAARRDELEGILEEVSKRLEIEEQKAKKADSESRKLTEMVRHLEENLEDEER 974
Query: 2890 XXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKH 3069
+K +++ +D+ + L+++L+D ER+K
Sbjct: 975 SRQKLLLEKNSIESRLKELEAQGLELEDSGNKLSKEKKALEERCEDLSSRLIDEVERSKQ 1034
Query: 3070 GVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQ 3249
VKAK RLE + E+ +L +E+Q + E +R +L + ++ EK K EEL NQ
Sbjct: 1035 LVKAKARLEATVAEINDELEKEKQQRHNAETARRAAETQLREEQESCLEKTRKAEELTNQ 1094
Query: 3250 LMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREV 3429
LM+++ EL R DEE A +++++R+++ +D+ E+ E+ AR KAE RR++
Sbjct: 1095 LMRKESELSQISIRNDEELAARQQLEREIREIRAQLDDAIEETNKEKAARQKAEKARRDM 1154
Query: 3430 VAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQ 3609
+LE K ++ + D+ + L +++DEE ++ +E+ + E +EE KA+ ++
Sbjct: 1155 AEELESYKQELEESNDKTVLHSQLKAKRDEEYAHLQKQLEETVKSSEEVVEEMKAQNQKK 1214
Query: 3610 VEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEI 3789
+EEL++ I+Q K+Q+ +K ++ A+ + + E++ + ++R + +KKRK E LME
Sbjct: 1215 IEELNETIDQLKRQKISADKAKSSAESDNENFRAELSNIASARLEAEKKRKAAETSLMEK 1274
Query: 3790 QANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXX 3969
+ E + L+ +L + +EL+ + + + +E +N+ ++ A+
Sbjct: 1275 DHKMREMQSNLDDLMAKLSKMNNELESIQKAKSADETLNSNLLKKNASLDMQLSELTEAS 1334
Query: 3970 XXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESV 4149
R + N+ RQLE++ ++ +++A + +EKE+ + EAR+K +E
Sbjct: 1335 EEDRRTRATLNNKIRQLEEDLAVAVEARDDALDAQEKIEKEVKEVKSLLAEARKKLDEEN 1394
Query: 4150 NQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDS 4329
+ +EELRKK +++ +++ + +E A+++ ++KKK QE ED EL +V A+ R+
Sbjct: 1395 REVMEELRKKKEKELSAEKERADMAEQARDKAERAKKKAIQEAEDVQKELTDVVAATREM 1454
Query: 4330 EKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVR 4509
E++ +KF+ Q+AEER A +RD Q LRD ET+ L L NE+ K+ +++ ++ +
Sbjct: 1455 ERKMRKFDQQLAEERNNTLLAQQERDMAHQMLRDAETKALVLSNELSEKKDIVDQLEKDK 1514
Query: 4510 RSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLE 4689
R+L+ E+ + S KDD GKNV+ELEK KR L+ EL+ Q+ ELED LQ+A+DAR R+E
Sbjct: 1515 RTLKLEIDNLASTKDDAGKNVYELEKTKRRLDEELSRAEQQIIELEDALQLADDARSRVE 1574
Query: 4690 VTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQI 4869
V QA++SE +R +++++ + +++++GL +IR+L ELE+E+R + A++++KKIE+QI
Sbjct: 1575 VNMQAMRSEFERQLASREEDEDDRKKGLTSKIRNLTEELESEQRARQAAIANKKKIESQI 1634
Query: 4870 GELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVE 5049
EL ++ E + R E+ + Q++ EAR A ED A R+A+++ RA E
Sbjct: 1635 SELTEKNEASLRQIEDLSRQLRKAQLGWKDLQLDVTEARAAMEDALAGQRDAEKRARASE 1694
Query: 5050 AEREQLREANEGLMQARK--QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXX 5223
E ++L + + +++ + + S+EEKRRLEAK+
Sbjct: 1695 DEIKRLTADIQAVSSSKRKAEAERDELIEEVSSLRASSFSNEEKRRLEAKVIDLEDQLDE 1754
Query: 5224 XQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESG 5403
S ELA +K RK+Q QLEQ+T DL+MER++ ++TE++K +LER+NRD K ++ + E+
Sbjct: 1755 EASANELAQEKVRKSQQQLEQMTADLAMERSVCERTESDKIALERANRDLKQQLQDAENT 1814
Query: 5404 AQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQ 5583
A +R R Q+ EAKV LE QL++E Q+K R RR+E ++ + Q E+EKR E
Sbjct: 1815 AVARLRTQINVAEAKVSSLEQQLSLEEQDKMRQGRTLRRMETKMAEMQQMLEEEKRQGES 1874
Query: 5584 AKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
++ +++ N + R LR QL++ E E R K ++ +R A+++ D NE L+R++
Sbjct: 1875 NRQAVDRQNARIRQLRTQLEDTEAERDRLTNKLKDERRRAEEMTDLNETLSRDV 1928
Score = 44.3 bits (103), Expect = 0.036
Identities = 37/163 (22%), Positives = 69/163 (41%), Gaps = 6/163 (3%)
Frame = +1
Query: 5278 LEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQ------SRARAQMAAL 5439
LE+++ L +E +K ++E + L R + + + E Q + +++ L
Sbjct: 934 LEEVSKRLEIEEQKAKKADSESRKLTEMVRHLEENLEDEERSRQKLLLEKNSIESRLKEL 993
Query: 5440 EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKN 5619
EA+ LED N +EK A L RL D ++ + +A + + + + N +
Sbjct: 994 EAQGLELEDSGNKLSKEKKALEERCEDLSSRLIDEVERSKQLVKAKARLEATVAEINDEL 1053
Query: 5620 RNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
++Q AE T+ R Q + E+LT +LM
Sbjct: 1054 EKEKQQRHNAETARRAAETQLREEQESCLEKTRKAEELTNQLM 1096
>gi|1477559|gb|AAC47238.1| non-muscle myosin heavy chain II
Length = 2003
Score = 1649 bits (4269), Expect = 0.0
Identities = 865/1914 (45%), Positives = 1264/1914 (65%), Gaps = 14/1914 (0%)
Frame = +1
Query: 46 DPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDE--VLVELVDTSRQVTISRDDVQKAN 219
+P+ A WA++KL WVP + +GF +G++ E + + + +EL++T + +S DD QK N
Sbjct: 22 NPSISADWAKKKLMWVPSEKDGFALGAVIGEPHADGTIDIELMETGERQRVSSDDYQKPN 81
Query: 220 PPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIE 399
PPK+DK EDMS LT LNEASVLHNLK RY+S+L YTYSGLFCVVINPYK++PIY++ + E
Sbjct: 82 PPKYDKCEDMSMLTCLNEASVLHNLKQRYFSNLYYTYSGLFCVVINPYKRIPIYTDTIAE 141
Query: 400 EFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAG 579
+FK KKR EMPPHIFA+AD AYRSMLQER+DQSILCTGESGAGKTENTKKVIQYLA+VA
Sbjct: 142 QFKCKKRKEMPPHIFAVADEAYRSMLQERDDQSILCTGESGAGKTENTKKVIQYLAYVA- 200
Query: 580 ATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFI 759
N+S+ + ++ +G+LE QLLQANPILEAFGNSKTVKNDNSSRFGKFI
Sbjct: 201 ---NRSMVKNRKTSVDLDTSTNRIMGQLEEQLLQANPILEAFGNSKTVKNDNSSRFGKFI 257
Query: 760 RINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLE-GVD 936
R++FD +G ISGANIEFYLLEKSRVL+QA +ERSFHIFYQ+L+G S ++ YLLE +
Sbjct: 258 RVHFDSTGCISGANIEFYLLEKSRVLKQAPNERSFHIFYQLLKGLSKVQREHYLLEDSLS 317
Query: 937 NYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEK 1116
Y+F+ N L VDD E T+N+M IMG D+EI I+RVVSAV+L GNLEF+ E
Sbjct: 318 KYKFVSNGDSKLAGVDDGAEMKETLNAMSIMGLNDEEIGGILRVVSAVMLFGNLEFSHEN 377
Query: 1117 KS-DQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAI 1293
K+ DQA+L +D V QK+ LLG+ V EL +AFL+P+IKV R+ V++AQ+ +Q F+V AI
Sbjct: 378 KNNDQAVLLNDAVAQKIASLLGVNVTELMRAFLKPKIKVQRDLVHRAQSVDQVNFSVGAI 437
Query: 1294 AKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQ 1473
AKASYERLF+WLV R+NKSLDRT +Q SFIGILDIAGFEIF+ NSFEQ+CINYTNEKLQ
Sbjct: 438 AKASYERLFRWLVHRLNKSLDRTRQQSVSFIGILDIAGFEIFETNSFEQLCINYTNEKLQ 497
Query: 1474 QLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDK 1653
QLFNNTMF+ EQ+EY EG+EW F+DFGL+LQPTIDLI+KPMG+++ LD+ CLFP+ ND+
Sbjct: 498 QLFNNTMFVREQQEYLDEGLEWKFLDFGLNLQPTIDLIDKPMGIMSTLDDVCLFPQGNDQ 557
Query: 1654 SFVEKLQKTHNKHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQ 1833
SFV++L TH++HPK++VP++RS+S FAVVHYAGRVDY ++ W +KNMDPLNENV+ +++
Sbjct: 558 SFVQRLNNTHSQHPKYVVPEIRSRSDFAVVHYAGRVDYQSEGWRVKNMDPLNENVIDVLK 617
Query: 1834 NSTDPFVAGIWKD-AEFAGICAAEMNETA--FGMR-SRKGMFRTVSQLHKEQLTKLMTTL 2001
S + + +WKD A+ + AA+ FG R +KGMFRTVSQL+KEQL +LM+TL
Sbjct: 618 TSKESLIVDMWKDIADVCSLSAADSTSDTGVFGSRVPKKGMFRTVSQLYKEQLARLMSTL 677
Query: 2002 RNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRY 2181
NT+PHFVRCIIPNHEKK G +N++LVL+QLRCNGVLEGIRICRQGFP R+PFQEFR RY
Sbjct: 678 NNTNPHFVRCIIPNHEKKHGVLNAHLVLDQLRCNGVLEGIRICRQGFPTRLPFQEFRQRY 737
Query: 2182 E-ILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLT 2358
E +L PDV P F+DGK +V +++ L++D NL+RIGQSK+FFR+GV+A EE RD KL+
Sbjct: 738 EKLLAPDVNPAGFMDGKNAVYRIVQYLEVDANLFRIGQSKIFFRSGVIAEFEEMRDQKLS 797
Query: 2359 ALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQV 2538
ALI +FQAQCRG+L RR+ NGLA+++LR WQWWRL TKVKPLL+V
Sbjct: 798 ALIESFQAQCRGWLGRRVMVRRREQEVAIKILQRNGLAWMRLREWQWWRLLTKVKPLLEV 857
Query: 2539 TRTDDEIRAKDDELRATKERLLKME---HDFRENEKKLDQVIVERAVIQEQLQQESENSA 2709
T D+ I ++ EL+ T E+L + E D+++ +K+D+ ER V++ +L ES A
Sbjct: 858 TNKDELIAEREQELKVTAEKLRRSEVFISDYKQQMEKMDE---ERLVLKTRLDAESSERA 914
Query: 2710 ELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXX 2889
E+ + R R+ R ELE I+ ++ RL RK E VR
Sbjct: 915 EIFEERSRMAARRDELEGILEEVSKRLEIEEQKAKKADSESRKLTEMVRHLEENLEDEER 974
Query: 2890 XXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKH 3069
+K +++ +D+ + L+++L+D ER+K
Sbjct: 975 SRQKLLLEKNSIESRLKELEAQGLELEDSGNKLSKEKKALEERCEDLSSRLIDEVERSKQ 1034
Query: 3070 GVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQ 3249
VKAK RLE + E+ +L +E+Q + E +R +L + ++ EK K EEL NQ
Sbjct: 1035 LVKAKARLEATVAEINDELEKEKQQRHNAETARRAAETQLREEQESCLEKTRKAEELTNQ 1094
Query: 3250 LMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREV 3429
LM+++ EL R DEE A +++++R+++ +D+ E+ E+ AR KAE RR++
Sbjct: 1095 LMRKESELSQISIRNDEELAARQQLEREIREIRAQLDDAIEETNKEQAARQKAEKARRDM 1154
Query: 3430 VAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQ 3609
+LE K ++ + D+ + L +++DEE ++ +E+ + E +EE KA+ ++
Sbjct: 1155 AEELESYKQELEESNDKTVLHSQLKAKRDEEYAHLQKQLEETVKSSEEVVEEMKAQNQKK 1214
Query: 3610 VEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEI 3789
+EEL++ I+Q K+Q+ +K ++ A+ + + E++ + ++R + +KKRK E LME
Sbjct: 1215 IEELNETIDQLKRQKISADKAKSSAESDNENFRAELSNIASARLEAEKKRKAAETSLMEK 1274
Query: 3790 QANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXX 3969
+ E + L+ +L + +EL+ + + + +E +N+ ++ A+
Sbjct: 1275 DHKMREMQSNLDDLMAKLSKMNNELESIQKAKSADETLNSNLLKKNASLDMQLSELTEAS 1334
Query: 3970 XXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESV 4149
R + N+ RQLE++ ++ +++A + +EKE+ + EAR+K +E
Sbjct: 1335 EEDRRTRATLNNKIRQLEEDLAVAVEARDDALDAQEKIEKEVKEVKSLLAEARKKLDEEN 1394
Query: 4150 NQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDS 4329
+ +EELRKK +++ +++ + +E A+++ ++KKK QE ED EL +V A+ R+
Sbjct: 1395 REVMEELRKKKEKELSAEKERADMAEQARDKAERAKKKAIQEAEDVQKELTDVVAATREM 1454
Query: 4330 EKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVR 4509
E++ +KF+ Q+AEER A +RD Q LRD ET+ L L NE+ K+ +++ ++ +
Sbjct: 1455 ERKMRKFDQQLAEERNNTLLAQQERDMAHQMLRDAETKALVLSNELSEKKDIVDQLEKDK 1514
Query: 4510 RSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLE 4689
R+L+ E+ + S KDD GKNV+ELEK KR L+ EL+ Q+ ELED LQ+A+DAR R+E
Sbjct: 1515 RTLKLEIDNLASTKDDAGKNVYELEKTKRRLDEELSRAEQQIIELEDALQLADDARSRVE 1574
Query: 4690 VTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQI 4869
V QA++SE +R +++++ + +++++GL +IR+L ELE+E+R + A++++KKIE+QI
Sbjct: 1575 VNMQAMRSEFERQLASREEDEDDRKKGLTSKIRNLTEELESEQRARQAAIANKKKIESQI 1634
Query: 4870 GELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVE 5049
EL ++ E + R E+ + Q++ EAR A ED A R+A+++ RA E
Sbjct: 1635 SELTEKNEASLRQIEDLSRQLRKAQLGWKDLQLDVTEARAAMEDALAGQRDAEKRARASE 1694
Query: 5050 AEREQLREANEGLMQARK--QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXX 5223
E ++L + + +++ + + S+EEKRRLEAK+
Sbjct: 1695 DEIKRLTADIQAVSSSKRKAEAERDELIEEVSSLRASSFSNEEKRRLEAKVIDLEDQLDE 1754
Query: 5224 XQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESG 5403
S ELA +K RK+Q QLEQ+T DL+MER++ ++TE++K +LER+NRD K ++ + E+
Sbjct: 1755 EASANELAQEKVRKSQQQLEQMTADLAMERSVCERTESDKIALERANRDLKQQLQDAENT 1814
Query: 5404 AQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQ 5583
A +R R Q+ EAKV LE QL++E Q+K R RR+E ++ + Q E+EKR E
Sbjct: 1815 AVARLRTQINVAEAKVSSLEQQLSLEEQDKMRQGRTLRRMETKMAEMQQMLEEEKRQGES 1874
Query: 5584 AKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
++ +++ N + R LR QL++ E E R K ++ +R A+++ D NE L+R++
Sbjct: 1875 NRQAVDRQNARIRQLRTQLEDTEAERDRLTNKLKDERRRAEEMTDLNETLSRDV 1928
Score = 44.3 bits (103), Expect = 0.036
Identities = 37/163 (22%), Positives = 69/163 (41%), Gaps = 6/163 (3%)
Frame = +1
Query: 5278 LEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQ------SRARAQMAAL 5439
LE+++ L +E +K ++E + L R + + + E Q + +++ L
Sbjct: 934 LEEVSKRLEIEEQKAKKADSESRKLTEMVRHLEENLEDEERSRQKLLLEKNSIESRLKEL 993
Query: 5440 EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKN 5619
EA+ LED N +EK A L RL D ++ + +A + + + + N +
Sbjct: 994 EAQGLELEDSGNKLSKEKKALEERCEDLSSRLIDEVERSKQLVKAKARLEATVAEINDEL 1053
Query: 5620 RNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
++Q AE T+ R Q + E+LT +LM
Sbjct: 1054 EKEKQQRHNAETARRAAETQLREEQESCLEKTRKAEELTNQLM 1096
>gi|2104553|gb|AAC31665.1| Myosin heavy chain (MHY11) (5'partial)
[Homo sapiens]
Length = 1857
Score = 1646 bits (4262), Expect = 0.0
Identities = 858/1820 (47%), Positives = 1225/1820 (67%), Gaps = 13/1820 (0%)
Frame = +1
Query: 325 TYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSIL 504
TYSGLFCVV+NPYK LPIYSE +++ +KGKKRHEMPPHI+AIADTAYRSMLQ+REDQSIL
Sbjct: 1 TYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSIL 60
Query: 505 CTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQA 684
CTGESGAGKTENTKKVIQYLA VA + + K + GELE QLLQA
Sbjct: 61 CTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSIT--------------GELEKQLLQA 106
Query: 685 NPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSF 864
NPILEAFGN+KTVKNDNSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+F
Sbjct: 107 NPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTF 166
Query: 865 HIFYQILRGCSAKEKSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADD 1044
HIFY ++ G K +S+ LLEG +NY FL N + +P D + F T+ +M IMGF+++
Sbjct: 167 HIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEE 226
Query: 1045 EISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRI 1224
E SI++VVS+VL LGN+ F +E+ +DQA + D+ QKVCHL+G+ V + ++ L PRI
Sbjct: 227 EQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRI 286
Query: 1225 KVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIA 1404
KVGR+ V KAQ +EQA+FAVEA+AKA+YERLF+W++TR+NK+LD+THRQGASF+GILDIA
Sbjct: 287 KVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIA 346
Query: 1405 GFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDL 1584
GFEIF++NSFEQ+CINYTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP I+L
Sbjct: 347 GFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIEL 406
Query: 1585 IEK---PMGVLALLDEECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYA 1752
IE+ P GVLALLDEEC FPKA DKSFVEKL HPKF P ++ K+ F+++HYA
Sbjct: 407 IERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYA 466
Query: 1753 GRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF-- 1920
G+VDY+A WL KNMDPLN+NV L+ S+D FVA +WKD + G+ A+M E++
Sbjct: 467 GKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPS 526
Query: 1921 GMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRC 2100
+++KGMFRTV QL+KEQL KLMTTLRNT+P+FVRCIIPNHEK+SGK+++ LVLEQLRC
Sbjct: 527 ASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRC 586
Query: 2101 NGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLY 2280
NGVLEGIRICRQGFPNR+ FQEFR RYEIL + IPK F+DGK++ MI AL++D NLY
Sbjct: 587 NGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLY 646
Query: 2281 RIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXX 2460
RIGQSK+FFRTGVLAHLEEERDLK+T +IM FQA CRG+L+R+ +
Sbjct: 647 RIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQR 706
Query: 2461 NGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKK 2640
N AYLKLRNWQWWRLFTKVKPLLQVTR ++E++AK+DEL+ TKER K E++ +E E+K
Sbjct: 707 NCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQK 766
Query: 2641 LDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXX 2820
Q+ E+ ++QEQLQ E+E AE +++R RL + QELE I+++M RL
Sbjct: 767 HSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQL 826
Query: 2821 XXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXX 3000
R+K + + D +K + D +
Sbjct: 827 QAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKER 886
Query: 3001 XXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLL 3180
LTT L + EE+AK+ K K + E+ + ELE L +E + + ELE+ KRKL
Sbjct: 887 KLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLE 946
Query: 3181 AELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTID 3360
+ D + +A+ ++ EL QL K++EELQ L R D+E A K++R+++ I
Sbjct: 947 GDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHIS 1006
Query: 3361 ELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKR 3540
+L+ED+++ER ARNKAE +R++ +LE +K ++ D +D Q+L +++++EV K+
Sbjct: 1007 DLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKK 1066
Query: 3541 AIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIA 3720
A+++ + E +++E + K ++ VEEL +Q+EQ K+ ++ L+K + ++E AD+A E+
Sbjct: 1067 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELR 1126
Query: 3721 LLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEH 3900
+L ++ +++ K+K EA + E+Q+ ++ + + L D++ + ++E++ + + E E
Sbjct: 1127 VLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEG 1186
Query: 3901 AFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAH 4080
+ + +A+ TR K+ + RQLE+E+N+L D+ +E + +
Sbjct: 1187 KAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQN 1246
Query: 4081 LEKEIHAARQGAGEARRKAEE--SVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQS 4254
LE+ I ++++K ++ S + LEE +K+ +++E+L +Q EE A +++ ++
Sbjct: 1247 LERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKT 1306
Query: 4255 KKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDR 4434
K ++QQEL+D ++L+N R + EK+Q+KF+ +AEE+ K +RD E R++
Sbjct: 1307 KNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREK 1366
Query: 4435 ETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAEL 4614
ET+ LSL ++ E EE +R + L+ E++D +S+KDD GKNVHELEK+KR+LE ++
Sbjct: 1367 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1426
Query: 4615 NDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDL 4794
+M+ Q+EELED LQ EDA+LRLEV QALK + +R + +D + EEKRR L +Q+ +
Sbjct: 1427 EEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEY 1486
Query: 4795 ENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIEC 4974
E ELE+E++ ++ A + +KK+E + +LE Q + A + +EE ++Q E
Sbjct: 1487 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQREL 1546
Query: 4975 EEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRA--- 5145
E+AR ++++I A +E ++K +++EA+ QL+E +ARKQ A
Sbjct: 1547 EDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSL 1606
Query: 5146 KGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQ 5325
G +EKRRLEA+IAQ Q N E D+ RKA Q EQ++ +L+ ER+ Q
Sbjct: 1607 SGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQ 1666
Query: 5326 KTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAAN 5505
K E+ +Q LER N++ ++K+ E+E +S+ ++ +AALEAK+ LE+Q+ E +EK AA
Sbjct: 1667 KNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAAT 1726
Query: 5506 RAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHR 5685
++ ++ +K+L + Q EDE++ EQ KE EK N + + L+RQL+EAE+E R R
Sbjct: 1727 KSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRR 1786
Query: 5686 NVQREADDLLDANEQLTREL 5745
+QRE D+ ++NE + RE+
Sbjct: 1787 KLQRELDEATESNEAMGREV 1806
Score = 93.2 bits (230), Expect = 7e-17
Identities = 110/537 (20%), Positives = 206/537 (37%), Gaps = 25/537 (4%)
Frame = +1
Query: 4216 EESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKAL 4395
EE AKE LQ K+ QQ+ E+ ELE QK SQ+ EE+ +Q+ L
Sbjct: 736 EEEMQAKEDELQKTKERQQKAENELKELE------------QK--HSQLTEEKNLLQEQL 781
Query: 4396 LDRDAMSQELRDRETRVLSLLNEVDI----MKEHLEESDRVRRSLQQELQDSISNKDDFG 4563
+ E + R+ + E++ M+ LEE + + LQ E + D
Sbjct: 782 QAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLE 841
Query: 4564 KNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
+ + E E A++ L+ E ++++LED + + +D +L + L+ +N
Sbjct: 842 EQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNL- 900
Query: 4744 VEAEEKRRGLLK-------QIRDLENELENEKRGKSGAVSHRKKIEN------------- 4863
E EEK + L K I +LE L+ E++ + ++K+E
Sbjct: 901 AEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQ 960
Query: 4864 -QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFR 5040
QI EL+ QL + +EE + ++ R+ + I+ L + D +
Sbjct: 961 AQIAELKMQLA---KKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERA 1017
Query: 5041 AVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXX 5220
A +Q R+ E L + + + KR E + +
Sbjct: 1018 ARNKAEKQKRDLGEELEALKTELEDTLDSTATQQ------ELRAKREQEVTVLKKALDEE 1071
Query: 5221 XXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES 5400
++ +Q+ AQ +E++T L + + KQ+LE+ N D
Sbjct: 1072 TRSHEAQVQEMRQKHAQA-VEELTEQLEQFKRAKANLDKNKQTLEKENAD---------- 1120
Query: 5401 GAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANE 5580
L +L V GQ K ++LE ++ + + D +RA
Sbjct: 1121 -------------------LAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 1161
Query: 5581 QAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
+ + + K + ++ L+EAE + + ++ + D + ++ TR+ +N
Sbjct: 1162 ELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLN 1218
>gi|28972888|dbj|BAC65860.1| mKIAA3005 protein [Mus musculus]
Length = 1833
Score = 1642 bits (4252), Expect = 0.0
Identities = 861/1792 (48%), Positives = 1216/1792 (67%), Gaps = 13/1792 (0%)
Frame = +1
Query: 409 GKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATR 588
GKKRHEMPPHI+AI+++AYR MLQ+REDQSILCTGESGAGKTENTKKVIQYLAHVA + +
Sbjct: 1 GKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHK 60
Query: 589 NKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRIN 768
+ + N GELE QLLQANPILE+FGN+KTVKNDNSSRFGKFIRIN
Sbjct: 61 GRKDH--------------NIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRIN 106
Query: 769 FDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRF 948
FD++GYI GANIE YLLEKSR +RQA+DER+FHIFYQ+L G KS+ LLEG +NYRF
Sbjct: 107 FDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRF 166
Query: 949 LVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQ 1128
L N I +P D F T+ +M IMGF+ +EI S+++VVS+VL GN+ F +E+ +DQ
Sbjct: 167 LSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQ 226
Query: 1129 AMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASY 1308
A + ++ V QK+CHLLG+ V+E +A L PRIKVGR++V KAQ +EQA+FAVEA+AKA+Y
Sbjct: 227 ASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATY 286
Query: 1309 ERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNN 1488
ERLF+WLV RINK+LDRT RQGASFIGILDIAGFEIF++NSFEQ+CINYTNEKLQQLFN+
Sbjct: 287 ERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNH 346
Query: 1489 TMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDEECLFPKANDKSF 1659
TMFILEQEEYQREGIEW+FIDFGLDLQP IDLIE+P GVLALLDEEC FPKA DK+F
Sbjct: 347 TMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTF 406
Query: 1660 VEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQN 1836
VEKL + H KF P ++ K+ F ++HYAG+VDY AD+WLMKNMDPLN+NV L+
Sbjct: 407 VEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQ 466
Query: 1837 STDPFVAGIWKDAE-FAGI-CAAEMNETAFG--MRSRKGMFRTVSQLHKEQLTKLMTTLR 2004
S+D FVA +WKD + G+ M ETAFG +++KGMFRTV QL+KE LTKLM TLR
Sbjct: 467 SSDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLR 526
Query: 2005 NTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYE 2184
NT+P+FVRCIIPNHEK++GK++ +LVL+QLRCNGVLEGIRICRQGFPNR+ FQEFR RYE
Sbjct: 527 NTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYE 586
Query: 2185 ILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTAL 2364
ILTP+ IPK F+DGK++ +MI AL++D NLYRIGQSK+FFR GVLAHLEEERDLK+T +
Sbjct: 587 ILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDI 646
Query: 2365 IMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTR 2544
I+ FQA CRG+L+R+ + N AYLKLR+WQWWR+FTKVKPLLQVTR
Sbjct: 647 IIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTR 706
Query: 2545 TDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDI 2724
++E++AKD+EL KE+ K+E + E E+K Q++ E+ ++ EQLQ E+E AE +++
Sbjct: 707 QEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEM 766
Query: 2725 RGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXX 2904
R RL + QELE I++D+ R+ ++K ++D
Sbjct: 767 RARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKL 826
Query: 2905 XXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAK 3084
+K + +D ++QL + EE+AK+ K +
Sbjct: 827 QLEKVTAEAKIKKMEEEVLLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIR 886
Query: 3085 GRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRD 3264
+ E + +LE+ L +E + + ELE+ KRKL E D +D +AE +V+EL QL K++
Sbjct: 887 NKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQVDELKVQLTKKE 946
Query: 3265 EELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLE 3444
EELQ L R D+E+ + K R++Q I EL+ED E+E+ +RNKAE +R++ +LE
Sbjct: 947 EELQGALARGDDETLHKNNALKVARELQAQIAELQEDFESEKASRNKAEKQKRDLSEELE 1006
Query: 3445 KVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELH 3624
+K ++ D +D Q+L +++++EV K+A+E E +I++ + + + +EEL
Sbjct: 1007 ALKTELEDTLDTTAAQQELRTKREQEVAELKKALEDETKNHEAQIQDMRQRHATALEELS 1066
Query: 3625 DQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLA 3804
+Q+EQ K+ ++ LEK + + + ++A E+ +LQ +A+ + KRK +A + E+ A ++
Sbjct: 1067 EQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVS 1126
Query: 3805 ESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTR 3984
E D + L ++ + ++ELD+++ + EE E + A TR
Sbjct: 1127 EGDRLRVELAEKANKLQNELDNVSTLLEEAEKKGIKFAKDAAGLESQLQDTQELLQEETR 1186
Query: 3985 LKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVN--QQ 4158
K+ +R RQLE+EKN+L +++EE E R +LEK++ A + + ++K ++ + +
Sbjct: 1187 QKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIES 1246
Query: 4159 LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKR 4338
LEE +KK L+DVE L ++LEE +A +++ ++K ++QQEL+D +++L++ R + EK+
Sbjct: 1247 LEEAKKKLLKDVEALSQRLEEKVLAYDKLEKTKNRLQQELDDLTVDLDHQRQIVSNLEKK 1306
Query: 4339 QKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSL 4518
QKKF+ +AEE+ + +RD E R++ET+ LSL ++ E EE +R + L
Sbjct: 1307 QKKFDQLLAEEKGISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQL 1366
Query: 4519 QQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTN 4698
+ +++D +S+KDD GKNVHELEK+KR+LE ++ +MR Q+EELED LQ EDA+LRLEV
Sbjct: 1367 RADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNM 1426
Query: 4699 QALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGEL 4878
QA+K++ +R + +D + EEK+R LLKQ+R+LE ELE+E++ ++ AV+ +KK+E + +L
Sbjct: 1427 QAMKAQFERDLQTRDEQNEEKKRLLLKQVRELEAELEDERKQRALAVASKKKMEIDLKDL 1486
Query: 4879 EQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAER 5058
E Q+E AN+ ++E +YQ E EEAR ++++I A +E+++K +++EAE
Sbjct: 1487 EAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEI 1546
Query: 5059 EQLREANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQ 5229
QL+E +AR+ Q A G +EKRRLEA+IAQ Q
Sbjct: 1547 LQLQEELASSERARRHAEQERDELADEIANSASGKSALLDEKRRLEARIAQLEEELEEEQ 1606
Query: 5230 SNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQ 5409
SN EL D+ RK +Q++ + T+L+ ER+ QK++ +Q LER N++ KAK+ ELE +
Sbjct: 1607 SNMELLNDRFRKTTLQVDTLNTELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVK 1666
Query: 5410 SRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAK 5589
S+ +A ++ALEAK+ LE+QL E +E+ AAN+ RR EK+L + Q EDE+R +Q K
Sbjct: 1667 SKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYK 1726
Query: 5590 ELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
E +EK+N + + L+RQL+EAE+E +R R +QRE DD +ANE L+RE+
Sbjct: 1727 EQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREV 1778
Score = 83.2 bits (204), Expect = 7e-14
Identities = 117/608 (19%), Positives = 242/608 (39%), Gaps = 46/608 (7%)
Frame = +1
Query: 4066 GLRAHLEKE---------IHAARQGAGEARRKAEESVNQQLEELR--KKN---------- 4182
G+ AHLE+E I G RKA QQL L+ ++N
Sbjct: 630 GVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHW 689
Query: 4183 --------LRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKR 4338
++ + + +Q EE + E +L+ K+K Q ++E E+E K
Sbjct: 690 QWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEK-QTKVEGELEEMER---------KH 739
Query: 4339 QKKFESQ--MAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRR 4512
Q+ E + +AE+ A + + + M L ++ + +L++++ E EE +++ +
Sbjct: 740 QQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQ 799
Query: 4513 SLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEV 4692
+ ++++Q I D + + E E A++ L+ E +++++E+ + + ED + +
Sbjct: 800 NEKKKMQAHIQ---DLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEVLLLEDQNSKF-I 855
Query: 4693 TNQALKSESDRAISNKDVEAEEKRRGLLK-------QIRDLENELENEKRGKSGAVSHRK 4851
+ L + S++ E EEK + L K I DLE L+ E++ + ++
Sbjct: 856 KEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKR 915
Query: 4852 KIE-------NQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAA 5010
K++ +QI EL+ Q++ + + + A + ++ A
Sbjct: 916 KLDGETTDLQDQIAELQAQVDELKVQLTKKEEELQGALARGDDETLHKNNALKVARELQA 975
Query: 5011 LLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEA 5190
+ E F + +A R + + L + + A E + + E
Sbjct: 976 QIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAA----QQELRTKREQ 1031
Query: 5191 KIAQXXXXXXXXQSNCELAI-DKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNR 5367
++A+ N E I D +++ LE+++ L + E KQ LE N+
Sbjct: 1032 EVAELKKALEDETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNK 1091
Query: 5368 DYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTT 5547
+ ++ L+ ++A+ ++ +L+ + QE A RL L +
Sbjct: 1092 ELACEVKVLQQ------------VKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAE-- 1137
Query: 5548 QQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANE 5727
+AN+ EL S L L+EAE + + ++ + D + +
Sbjct: 1138 -------KANKLQNELDNVSTL--------LEEAEKKGIKFAKDAAGLESQLQDTQELLQ 1182
Query: 5728 QLTRELMN 5751
+ TR+ +N
Sbjct: 1183 EETRQKLN 1190
>gi|47214961|emb|CAG10783.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 2124
Score = 1633 bits (4229), Expect = 0.0
Identities = 905/2063 (43%), Positives = 1279/2063 (61%), Gaps = 152/2063 (7%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL V RA V +P A W ++L W+P + GF S+ E DEV+VEL + ++ +
Sbjct: 12 RYLFVDRALVYNPTAQADWTAKRLVWIPSERHGFEAASVGEERGDEVVVELAENGKKAVV 71
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDM+ELT LNEASVLHNLKDRYYS LIYTYSGLFCVVINPYK L
Sbjct: 72 NKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNL 131
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYS+++IE ++GKKRHE+PPHI+AI+++AYR MLQ+REDQSILCTGESGAGKTENTKKV
Sbjct: 132 PIYSDNIIEMYRGKKRHEIPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKV 191
Query: 553 IQYLAHVAGATRNKSLNAA----------AQQNIVQKPDVRNPIG-----ELEHQLLQAN 687
IQYLAHVA + R + ++ A + +PD +P+G ELE QLLQAN
Sbjct: 192 IQYLAHVASSHRGRKEHSLPCDDPERAQPAWKGGNPQPDP-SPLGGAHGGELERQLLQAN 250
Query: 688 PILEAFGNSKTVKNDNSSRF--------------GKFIRINFDMSGYISGANIEFYLLEK 825
PILE+FGN+KTVKNDNSSRF GKFIRINFD++GYI GANIE YLLEK
Sbjct: 251 PILESFGNAKTVKNDNSSRFVSEPSLTNCWTKAAGKFIRINFDVTGYIVGANIETYLLEK 310
Query: 826 SRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHS 1005
SR +RQA+DER+FH+FYQ+L G + + LLEG ++YRFL N + +P D + F
Sbjct: 311 SRAIRQAKDERTFHVFYQLLAGAGEHLRMDLLLEGFNSYRFLSNGHVPIPGQQDKENFQE 370
Query: 1006 TINSMRIMGFADDEIS------SIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQKVC 1167
T+ +M IM FA +EI ++++VVSAVL GN+ F +E+ +DQA + D+ QK+C
Sbjct: 371 TMEAMHIMSFAHEEILCRLTCFAMLKVVSAVLQFGNIVFKKERNTDQASMPDNTAAQKLC 430
Query: 1168 HLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRINK 1347
HLLG+ V+E +A L PRIKVGR++V KAQ +EQA+FA+EA+AKA+YERLF+WLV RIN+
Sbjct: 431 HLLGMNVMEFSRAILSPRIKVGRDYVQKAQTKEQADFAIEALAKATYERLFRWLVHRINR 490
Query: 1348 SLDRTHRQGASFIGILDIAGFEIFDI----------------------------NSFEQI 1443
+LDRT RQGASFIGILDIAGFEIF + NSFEQ+
Sbjct: 491 ALDRTKRQGASFIGILDIAGFEIFQVCFHPSCWCGGSSRCQQHPQTLPLLLLQLNSFEQL 550
Query: 1444 CINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLAL 1614
CINYTNEKLQQLFN+TMF+LEQEEYQREGIEW FIDFGLDLQP IDLIE+P GVLAL
Sbjct: 551 CINYTNEKLQQLFNHTMFVLEQEEYQREGIEWSFIDFGLDLQPCIDLIERPANPPGVLAL 610
Query: 1615 LDEECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMK 1791
LDEEC FPKA DK+FVEKL + H KF P ++ K+ F ++HYAGRVDY AD+WLMK
Sbjct: 611 LDEECWFPKATDKTFVEKLIQEQGSHGKFQKPRQLKDKADFCIIHYAGRVDYKADEWLMK 670
Query: 1792 NMDPLNENVVGLMQNSTDPFVAGIWKD--------AEFAGICAAE--------------- 1902
NMDPLN+NV L+ S+D FVA +WKD + + + + E
Sbjct: 671 NMDPLNDNVATLLHQSSDRFVAELWKDDIQSIQRASFYDNVTSLEEPAVDRIVGLDQVAG 730
Query: 1903 MNETAFGM--RSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSN 2076
M+ETAFG +++KGMFRTV QL+KE LTKLM TLRNT+P+FVRCIIPNHEK++GK+ +
Sbjct: 731 MSETAFGATYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLEPH 790
Query: 2077 LVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITA 2256
LVL+QLRCNGVLEGIRICRQGFPNR+ FQEFR RYEILTP IPK F+DGK++ +MI A
Sbjct: 791 LVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPSAIPKGFMDGKQACERMIQA 850
Query: 2257 LDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXX 2436
L++D NL+RIGQSK+FFRTGVLAHLEEERDLK+T +I+ FQ+ CRG+L+RR+Y
Sbjct: 851 LELDPNLFRIGQSKIFFRTGVLAHLEEERDLKITDVIIYFQSVCRGYLARRVYAKKQQQL 910
Query: 2437 XXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEH 2616
N AYLKLR+WQWWRLFTKVKPLLQVTR ++E++AKD+EL KE+ LK+E+
Sbjct: 911 SALKVLQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQEEEMQAKDEELMKVKEKKLKVEN 970
Query: 2617 DFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSX 2796
+ E E+K Q++ E+ ++ EQL E+E AE +++R RL TR QELE I++D+ R+
Sbjct: 971 ELVEMERKHQQLLEEKNILAEQLHAETELFAEAEEMRVRLLTRKQELEEILHDLESRVEE 1030
Query: 2797 XXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDA 2976
R+K ++D DK + +D
Sbjct: 1031 EEERNQSLQNERKKMQAHIQDLEEQLDEEEAARQKLQLDKVTAEAKIKKMEEENLLLEDH 1090
Query: 2977 YDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSEL 3156
+T+QL + EE+AK+ K K + E + +LE+ L +E + + EL
Sbjct: 1091 NSKLLKEKKLLDDRISEVTSQLAEEEEKAKNLSKLKNKQELMIVDLEERLKKEEKTRQEL 1150
Query: 3157 EQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQM 3336
E+ KRKL +EL D ++ + E + +E +QL K++EE Q L R DEE+A + KQ+
Sbjct: 1151 EKAKRKLDSELSDLQEQITELQTQSQETRSQLAKKEEETQAALCRSDEETAQKNIALKQV 1210
Query: 3337 RDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKD 3516
R++Q + EL+ED+E+E+ +R KAE +R++ +LE +K ++ D +D Q+L S+++
Sbjct: 1211 RELQAHLAELQEDLESEKTSRIKAEKLKRDLSEELEALKTELEDTLDTTAAQQELRSKRE 1270
Query: 3517 EEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQER 3696
+EV K+AI++ E +I+E + + + +EEL DQ+EQ ++ + LEK + +
Sbjct: 1271 QEVAELKKAIDEEARNHEAQIQEMRQRHTTALEELSDQLEQARRLKGSLEKNLQNLEGDN 1330
Query: 3697 ADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLN 3876
++ E+ LQ ++A+ + +RK EA L E+ + AE+++ K L ++ + ELD+++
Sbjct: 1331 KELGTEVKSLQQAKAESEYRRKKVEAQLQELLSRAAEAEKTKAELSERSHGLQVELDNVS 1390
Query: 3877 RVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKE 4056
EE E + + + TR K+ ++ RQLE EKN L++++E
Sbjct: 1391 ASLEESETKGVKLAKEVEKLSSKLQDLEDLQQEETRQKLNLSSQIRQLEVEKNTLVEQQE 1450
Query: 4057 EAEGLRAHLEKEIHAAR--------------------QGA---GEARRKAEESVN--QQL 4161
E E R +LEK++ + Q A E ++K +E V + L
Sbjct: 1451 EDEEARRNLEKQLQMLQAQVESGPPSRKIPEVLQWQTQAAFQLSETKKKLDEDVGVMEGL 1510
Query: 4162 EELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQ 4341
EELR+K +DVE ++LEE +A +++ ++K ++QQEL+D ++L++ R + EK+Q
Sbjct: 1511 EELRRKLQKDVELTTQRLEEKTIAMDKMDKTKSRLQQELDDLVVDLDHQRQLVSNLEKKQ 1570
Query: 4342 KKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQ 4521
KKF+ +AEE+ + +RD E R++ET+ LS+ ++ + EE +R+ + L+
Sbjct: 1571 KKFDQLLAEEKSISARYAEERDHAEAEAREKETKTLSMARALEEALDAKEELERLNKQLR 1630
Query: 4522 QELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQ 4701
E++D +S+KDD GKNVHELEK+KR+LE ++ +MR Q+EELED LQ EDA+LRLEV Q
Sbjct: 1631 AEMEDLMSSKDDVGKNVHELEKSKRTLEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQ 1690
Query: 4702 ALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELE 4881
A+K++ +R + ++ + EEK+R L+KQ+R++E ELE+E++ ++ AV+ +KK+E + ELE
Sbjct: 1691 AMKAQFERDLQAREEQGEEKKRALVKQVREMEAELEDERKQRALAVAGKKKLELDLNELE 1750
Query: 4882 QQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAERE 5061
Q E AN+ ++E +YQ E +EAR ++++I ++ ++K +++EAE
Sbjct: 1751 GQAEAANKGRDEAVKQLRKLQAQVKDYQRELDEARASRDEIFTQAKDNEKKLKSLEAEVL 1810
Query: 5062 QLREANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQS 5232
QL+E +AR+ Q G EEKRRLEA++AQ Q
Sbjct: 1811 QLQEEQAAAERARRHAEQERDELAEEISSSTSGKSSLLEEKRRLEARLAQLEEELEEEQG 1870
Query: 5233 NCELAIDKQRKAQVQ-LEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQ 5409
N EL D+ RKA +Q L ++ S+ ++ R+ A + GA+
Sbjct: 1871 NAELLNDRLRKATLQGLLPVSPAPSVPGGRPEQRVGCGAQRWPEERERSAAAGAPQQGAE 1930
Query: 5410 SRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQA- 5586
+A + +VQ L + + A A + E R +E A
Sbjct: 1931 GQAGGAGGDGQVQVQGLHQRAGGQAPAAGGAAGAGSKRESRGQQDAPPLREEAEGGAAAG 1990
Query: 5587 ------------------------------KELLEKSNLKNRNLRRQLDEAEDEMSRERT 5676
+EK+N + + L+RQL+EAE+E +R
Sbjct: 1991 GGRASARRPVQGAGRTAPPPLLRSISEPPSPPQMEKANSRLKQLKRQLEEAEEEATRANA 2050
Query: 5677 KHRNVQREADDLLDANEQLTREL 5745
R +QRE D+ +A+E L+REL
Sbjct: 2051 SRRKLQRELDEAGEASEALSREL 2073
>gi|29336026|ref|NP_082297.1| nonmuscle myosin heavy chain [Mus
musculus]
gi|28801584|gb|AAO47092.1| nonmuscle myosin heavy chain [Mus
musculus]
Length = 1992
Score = 1630 bits (4222), Expect = 0.0
Identities = 862/1906 (45%), Positives = 1247/1906 (65%), Gaps = 13/1906 (0%)
Frame = +1
Query: 67 WAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIED 246
W R++ WVP + GF +++ E +E VEL ++ R++ + RD +Q+ NPPKF K ED
Sbjct: 46 WTARRMVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAED 105
Query: 247 MSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHE 426
M+ELT LNEASVLHNL++RYYS LIYTYSGLFCVVINPYK+LPIY+E ++E ++GKKRHE
Sbjct: 106 MAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHE 165
Query: 427 MPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNA 606
+PPH++A+ + AYRSMLQ+REDQSILCTGESGAGKTENTKKVIQYLAHVA + + +
Sbjct: 166 VPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGR---- 221
Query: 607 AAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGY 786
++P V GELE QLLQANPILEAFGN+KTVKNDNSSRFGKFIRINFD++GY
Sbjct: 222 -------KEPGVP---GELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDIAGY 271
Query: 787 ISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRFLVNRGI 966
I GANIE YLLEKSR +RQA+DE SFHIFYQ+L G + K++ LLE +YRFL N
Sbjct: 272 IVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPS 331
Query: 967 TLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDD 1146
+ P + + F T+ S+R++G +EI++++R VSAVL GN+ +E+ +DQA + D+
Sbjct: 332 SSPG-QERELFQETLESLRVLGLLPEEITAMLRTVSAVLQFGNIVLKKERNTDQATMPDN 390
Query: 1147 RVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKW 1326
QK+C LLGL V + +A L PRIKVGR++V KAQ +EQA+FA+EA+AKA+YERLF+W
Sbjct: 391 TAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRW 450
Query: 1327 LVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILE 1506
LV R+N++LDR+ RQGASF+GILDIAGFEIF +NSFEQ+CINYTNEKLQQLFN+TMF+LE
Sbjct: 451 LVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLE 510
Query: 1507 QEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDEECLFPKANDKSFVEKLQK 1677
QEEYQREGI W F+DFGLDLQP IDLIE+P G+LALLDEEC FPKA DKSFVEK+ +
Sbjct: 511 QEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQ 570
Query: 1678 THNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFV 1854
HPKF P ++R ++ F+V+HYAG+VDY A +WLMKNMDPLN+NV L+ STD
Sbjct: 571 EQGSHPKFQRPRNLRDQADFSVLHYAGKVDYKASEWLMKNMDPLNDNVAALLHQSTDRLT 630
Query: 1855 AGIWKDAEFAGICAAE----MNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHF 2022
A IWKD E GI E + + G R R+GMFRTV QL+KE L++LM TL NT+P F
Sbjct: 631 AEIWKDVE--GIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSF 688
Query: 2023 VRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDV 2202
VRCI+PNHEK++GK+ LVL+QLRCNGVLEGIRICRQGFPNR+ FQEFR RYEILTP+
Sbjct: 689 VRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNA 748
Query: 2203 IPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQA 2382
IPK F+DGK++ KMI AL++D NLYR+GQSK+FFR GVLA LEEERDLK+T +I++FQA
Sbjct: 749 IPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQA 808
Query: 2383 QCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIR 2562
RG+L+RR + N AYLKLRNWQWWRLF KVKPLLQVTR D+ ++
Sbjct: 809 AARGYLARRAFQRRQQQQSALRVMQRNCAAYLKLRNWQWWRLFIKVKPLLQVTRQDEVLQ 868
Query: 2563 AKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQT 2742
A+ EL+ +E + + E + ++ Q+ ER + EQL+ E+E +E ++ R RL
Sbjct: 869 ARAQELQKVQELQQQSAREVGELQGRVAQLEEERTRLAEQLRAEAELCSEAEETRARLAA 928
Query: 2743 RNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTN 2922
R QELE +V ++ R+ +++ + +++ +K
Sbjct: 929 RKQELELVVTELEARVGEEEECSRQLQSEKKRLQQHIQELESHLEAEEGARQKLQLEKVT 988
Query: 2923 VDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQ 3102
+ +D ++Q + EE+ K K + + E
Sbjct: 989 TEAKMKKFEEDLLLLEDQNSKLSKERRLLEERLAEFSSQAAEEEEKVKSLNKLRLKYEAT 1048
Query: 3103 LHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQ 3282
+ ++E L +E + + ELE+ KR+L E + ++ + E+ + EEL QL ++++ELQ
Sbjct: 1049 ISDMEDRLKKEEKGRQELEKLKRRLDGESSELQEQMVEQKQRAEELLAQLGRKEDELQAA 1108
Query: 3283 LTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDV 3462
L R +EE + K +R+ Q + E +ED+E ER AR KAE RR++ +LE ++G++
Sbjct: 1109 LLRAEEEGGARAQLLKSLREAQAGLAEAQEDLEAERVARAKAEKQRRDLGEELEALRGEL 1168
Query: 3463 LDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQH 3642
D +D Q+L S++++EV K+A+E+ E ++E + + S+ + E+ +Q+EQ
Sbjct: 1169 EDTLDSTNAQQELRSKREQEVTELKKALEEESRAHEVSMQELRQRHSQALVEMAEQLEQA 1228
Query: 3643 KKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHK 3822
++ + EK + + E +++ E++ LQ SR + ++KR+ E+ L E+Q ++S+ +
Sbjct: 1229 RRGKGVWEKTRLSLEAEVSELKAELSSLQTSRQEGEQKRRRLESQLQEVQGRSSDSERAR 1288
Query: 3823 RTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANI 4002
++L+R++ EL+ ++ E E + + L++A TR K+A
Sbjct: 1289 SEAAEKLQRAQAELESVSTALSEAESKAIRLGKELSSAESQLHDTQELLQEETRAKLALG 1348
Query: 4003 NRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEE--SVNQQLEELRK 4176
+R R LE E L ++ EE R +E+ + + E RR+ EE +V + EE R+
Sbjct: 1349 SRVRALEAEAAGLREQMEEEVVARERAGRELQSTQAQLSEWRRRQEEEAAVLEAGEEARR 1408
Query: 4177 KNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFES 4356
+ R+ E L ++L E A ER+ ++++++QQEL+D++++L + EK+Q+KF+
Sbjct: 1409 RAAREAETLTQRLAEKTEAVERLERARRRLQQELDDATVDLGQQKQLLSTLEKKQRKFDQ 1468
Query: 4357 QMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQD 4536
+AEE+ AV +A+ DR+ + E R+RE R LSL ++ +E EE +R R+L+ EL+
Sbjct: 1469 LLAEEKAAVLRAVEDRERIEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEA 1528
Query: 4537 SISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSE 4716
+S+KDD GKNVHELE+A+++ E +D+R Q+ ELED L AEDA+LRLEVT QALK++
Sbjct: 1529 LLSSKDDVGKNVHELERARKAAEQAASDLRTQVTELEDELTAAEDAKLRLEVTVQALKAQ 1588
Query: 4717 SDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEV 4896
+R + +D EE+RR L KQ+RD E E + E++ ++ A++ RKK+E ++ EL+ Q
Sbjct: 1589 HERDLQGRDDAGEERRRQLAKQLRDAEVERDEERKQRALAMAARKKLELELEELKAQTSA 1648
Query: 4897 ANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREA 5076
A + KEE E E EE R +++++ L RE ++K + +EAE +L+E
Sbjct: 1649 AGQGKEEAVKQLKKMQVQMKELWREVEETRSSRDEMFTLSRENEKKLKGLEAEVLRLQEE 1708
Query: 5077 NEGLMQARKQXXXXXXXXXXXRAKGG---GISSEEKRRLEAKIAQXXXXXXXXQSNCELA 5247
+AR+Q A G + EEKR+LE +++Q Q+N EL
Sbjct: 1709 LAASDRARRQAQQDRDEMAEEVASGNLSKAATLEEKRQLEGRLSQLEEELEEEQNNSELL 1768
Query: 5248 IDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQ 5427
D RK +Q+E +TT+LS ER+ + K E+ +Q LER ++ +A++ E ++GA++R +
Sbjct: 1769 KDHYRKLVLQVESLTTELSAERSFSAKAESGRQQLERQIQELRARLGEEDAGARARQKML 1828
Query: 5428 MAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKS 5607
+AALE+K+ E+QL E +E+ + + RR EKRL + Q ++E+R +Q ++ LEKS
Sbjct: 1829 IAALESKLAQAEEQLEQESRERILSGKLVRRAEKRLKEVVLQVDEERRVADQVRDQLEKS 1888
Query: 5608 NLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
NL+ + L+RQL+EAE+E SR + R +QRE +D+ ++ E + RE+
Sbjct: 1889 NLRLKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREV 1934
Score = 43.1 bits (100), Expect = 0.081
Identities = 35/205 (17%), Positives = 94/205 (45%), Gaps = 12/205 (5%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGK--------VEELN 3243
+L Q+ L +L+ ER + ++ E +++L ++++ + L E+ + L
Sbjct: 1774 KLVLQVESLTTELSAERSFSAKAESGRQQLERQIQELRARLGEEDAGARARQKMLIAALE 1833
Query: 3244 NQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRR 3423
++L + +E+L+ + V +K+++++ +DE R + R+ K+ + +
Sbjct: 1834 SKLAQAEEQLEQESRERILSGKLVRRAEKRLKEVVLQVDEERRVADQVRDQLEKSNLRLK 1893
Query: 3424 EVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFS 3603
++ QLE+ + ++ A + + R+ E+V + ++ + T+ ++ F+
Sbjct: 1894 QLKRQLEEAE----EEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFT 1949
Query: 3604 ----RQVEELHDQIEQHKKQRSQLE 3666
RQV L + + +++ E
Sbjct: 1950 TRTVRQVFRLEEGVASDEEEAEGAE 1974
>gi|33638127|gb|AAQ24173.1| nonmuscle myosin II-C heavy chain [Mus
musculus]
Length = 2000
Score = 1630 bits (4220), Expect = 0.0
Identities = 862/1911 (45%), Positives = 1248/1911 (65%), Gaps = 18/1911 (0%)
Frame = +1
Query: 67 WAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIED 246
W R++ WVP + GF +++ E +E VEL ++ R++ + RD +Q+ NPPKF K ED
Sbjct: 46 WTARRMVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAED 105
Query: 247 MSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHE 426
M+ELT LNEASVLHNL++RYYS LIYTYSGLFCVVINPYK+LPIY+E ++E ++GKKRHE
Sbjct: 106 MAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHE 165
Query: 427 MPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNA 606
+PPH++A+ + AYRSMLQ+REDQSILCTGESGAGKTENTKKVIQYLAHVA + + +
Sbjct: 166 VPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGR---- 221
Query: 607 AAQQNIVQKPDVRNPI-----GELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINF 771
++P V + GELE QLLQANPILEAFGN+KTVKNDNSSRFGKFIRINF
Sbjct: 222 -------KEPGVPASVSTMSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINF 274
Query: 772 DMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRFL 951
D++GYI GANIE YLLEKSR +RQA+DE SFHIFYQ+L G + K++ LLE +YRFL
Sbjct: 275 DIAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFL 334
Query: 952 VNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQA 1131
N + P + + F T+ S+R++G +EI++++R VSAVL GN+ +E+ +DQA
Sbjct: 335 TNGPSSSPG-QERELFQETLESLRVLGLLPEEITAMLRTVSAVLQFGNIVLKKERNTDQA 393
Query: 1132 MLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYE 1311
+ D+ QK+C LLGL V + +A L PRIKVGR++V KAQ +EQA+FA+EA+AKA+YE
Sbjct: 394 TMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYE 453
Query: 1312 RLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNT 1491
RLF+WLV R+N++LDR+ RQGASF+GILDIAGFEIF +NSFEQ+CINYTNEKLQQLFN+T
Sbjct: 454 RLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHT 513
Query: 1492 MFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDEECLFPKANDKSFV 1662
MF+LEQEEYQREGI W F+DFGLDLQP IDLIE+P G+LALLDEEC FPKA DKSFV
Sbjct: 514 MFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFV 573
Query: 1663 EKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNS 1839
EK+ + HPKF P ++R ++ F+V+HYAG+VDY A +WLMKNMDPLN+NV L+ S
Sbjct: 574 EKVAQEQGSHPKFQRPRNLRDQADFSVLHYAGKVDYKASEWLMKNMDPLNDNVAALLHQS 633
Query: 1840 TDPFVAGIWKDAEFAGICAAE----MNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRN 2007
TD A IWKD E GI E + + G R R+GMFRTV QL+KE L++LM TL N
Sbjct: 634 TDRLTAEIWKDVE--GIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSN 691
Query: 2008 TSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEI 2187
T+P FVRCI+PNHEK++GK+ LVL+QLRCNGVLEGIRICRQGFPNR+ FQEFR RYEI
Sbjct: 692 TNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEI 751
Query: 2188 LTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALI 2367
LTP+ IPK F+DGK++ KMI AL++D NLYR+GQSK+FFR GVLA LEEERDLK+T +I
Sbjct: 752 LTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDII 811
Query: 2368 MNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRT 2547
++FQA RG+L+RR + N AYLKLRNWQWWRLF KVKPLLQVTR
Sbjct: 812 VSFQAAARGYLARRAFQRRQQQQSALRVMQRNCAAYLKLRNWQWWRLFIKVKPLLQVTRQ 871
Query: 2548 DDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIR 2727
D+ ++A+ EL+ +E + + E + ++ Q+ ER + EQL+ E+E +E ++ R
Sbjct: 872 DEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERTRLAEQLRAEAELCSEAEETR 931
Query: 2728 GRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXX 2907
RL R QELE +V ++ R+ +++ + +++
Sbjct: 932 ARLAARKQELELVVTELEARVGEEEECSRQLQSEKKRLQQHIQELESHLEAEEGARQKLQ 991
Query: 2908 XDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKG 3087
+K + +D ++Q + EE+ K K +
Sbjct: 992 LEKVTTEAKMKKFEEDLLLLEDQNSKLSKERRLLEERLAEFSSQAAEEEEKVKSLNKLRL 1051
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDE 3267
+ E + ++E L +E + + ELE+ KR+L E + ++ + E+ + EEL QL ++++
Sbjct: 1052 KYEATISDMEDRLKKEEKGRQELEKLKRRLDGESSELQEQMVEQKQRAEELLAQLGRKED 1111
Query: 3268 ELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEK 3447
ELQ L R +EE + K +R+ Q + E +ED+E ER AR KAE RR++ +LE
Sbjct: 1112 ELQAALLRAEEEGGARAQLLKSLREAQAGLAEAQEDLEAERVARAKAEKQRRDLGEELEA 1171
Query: 3448 VKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
++G++ D +D Q+L S++++EV K+A+E+ E ++E + + S+ + E+ +
Sbjct: 1172 LRGELEDTLDSTNAQQELRSKREQEVTELKKALEEESRAHEVSMQELRQRHSQALVEMAE 1231
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAE 3807
Q+EQ ++ + EK + + E +++ E++ LQ SR + ++KR+ E+ L E+Q ++
Sbjct: 1232 QLEQARRGKGVWEKTRLSLEAEVSELKAELSSLQTSRQEGEQKRRRLESQLQEVQGRSSD 1291
Query: 3808 SDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL 3987
S+ + ++L+R++ EL+ ++ E E + + L++A TR
Sbjct: 1292 SERARSEAAEKLQRAQAELESVSTALSEAESKAIRLGKELSSAESQLHDTQELLQEETRA 1351
Query: 3988 KIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEE--SVNQQL 4161
K+A +R R LE E L ++ EE R +E+ + + E RR+ EE +V +
Sbjct: 1352 KLALGSRVRALEAEAAGLREQMEEEVVARERAGRELQSTQAQLSEWRRRQEEEAAVLEAG 1411
Query: 4162 EELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQ 4341
EE R++ R+ E L ++L E A ER+ ++++++QQEL+D++++L + EK+Q
Sbjct: 1412 EEARRRAAREAETLTQRLAEKTEAVERLERARRRLQQELDDATVDLGQQKQLLSTLEKKQ 1471
Query: 4342 KKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQ 4521
+KF+ +AEE+ AV +A+ DR+ + E R+RE R LSL ++ +E EE +R R+L+
Sbjct: 1472 RKFDQLLAEEKAAVLRAVEDRERIEAEGREREARALSLTRALEEEQEAREELERQNRALR 1531
Query: 4522 QELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQ 4701
EL+ +S+KDD GKNVHELE+A+++ E +D+R Q+ ELED L AEDA+LRLEVT Q
Sbjct: 1532 AELEALLSSKDDVGKNVHELERARKAAEQAASDLRTQVTELEDELTAAEDAKLRLEVTVQ 1591
Query: 4702 ALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELE 4881
ALK++ +R + +D EE+RR L KQ+RD E E + E++ ++ A++ RKK+E ++ EL+
Sbjct: 1592 ALKAQHERDLQGRDDAGEERRRQLAKQLRDAEVERDEERKQRALAMAARKKLELELEELK 1651
Query: 4882 QQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAERE 5061
Q A + KEE E E EE R +++++ L RE ++K + +EAE
Sbjct: 1652 AQTSAAGQGKEEAVKQLKKMQVQMKELWREVEETRSSRDEMFTLSRENEKKLKGLEAEVL 1711
Query: 5062 QLREANEGLMQARKQXXXXXXXXXXXRAKGG---GISSEEKRRLEAKIAQXXXXXXXXQS 5232
+L+E +AR+Q A G + EEKR+LE +++Q Q+
Sbjct: 1712 RLQEELAASDRARRQAQQDRDEMAEEVASGNLSKAATLEEKRQLEGRLSQLEEELEEEQN 1771
Query: 5233 NCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQS 5412
N EL D RK +Q+E +TT+LS ER+ + K E+ +Q LER ++ +A++ E ++GA++
Sbjct: 1772 NSELLKDHYRKLVLQVESLTTELSAERSFSAKAESGRQQLERQIQELRARLGEEDAGARA 1831
Query: 5413 RARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKE 5592
R + +AALE+K+ E+QL E +E+ + + RR EKRL + Q ++E+R +Q ++
Sbjct: 1832 RQKMLIAALESKLAQAEEQLEQESRERILSGKLVRRAEKRLKEVVLQVDEERRVADQVRD 1891
Query: 5593 LLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
LEKSNL+ + L+RQL+EAE+E SR + R +QRE +D+ ++ E + RE+
Sbjct: 1892 QLEKSNLRLKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREV 1942
Score = 43.1 bits (100), Expect = 0.081
Identities = 35/205 (17%), Positives = 94/205 (45%), Gaps = 12/205 (5%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGK--------VEELN 3243
+L Q+ L +L+ ER + ++ E +++L ++++ + L E+ + L
Sbjct: 1782 KLVLQVESLTTELSAERSFSAKAESGRQQLERQIQELRARLGEEDAGARARQKMLIAALE 1841
Query: 3244 NQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRR 3423
++L + +E+L+ + V +K+++++ +DE R + R+ K+ + +
Sbjct: 1842 SKLAQAEEQLEQESRERILSGKLVRRAEKRLKEVVLQVDEERRVADQVRDQLEKSNLRLK 1901
Query: 3424 EVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFS 3603
++ QLE+ + ++ A + + R+ E+V + ++ + T+ ++ F+
Sbjct: 1902 QLKRQLEEAE----EEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFT 1957
Query: 3604 ----RQVEELHDQIEQHKKQRSQLE 3666
RQV L + + +++ E
Sbjct: 1958 TRTVRQVFRLEEGVASDEEEAEGAE 1982
>gi|33563340|ref|NP_079005.2| myosin, heavy polypeptide 14; nonmuscle
myosin heavy chain II-C; myosin heavy chain 14 [Homo
sapiens]
gi|33438760|gb|AAO39147.1| myosin heavy chain [Homo sapiens]
Length = 1995
Score = 1624 bits (4206), Expect = 0.0
Identities = 860/1906 (45%), Positives = 1234/1906 (64%), Gaps = 13/1906 (0%)
Frame = +1
Query: 67 WAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIED 246
W R+L WVP + GF +++ E +E VEL ++ R++ + RD +Q+ NPPKF K ED
Sbjct: 50 WTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAED 109
Query: 247 MSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHE 426
M+ELT LNEASVLHNL++RYYS LIYTYSGLFCVVINPYK+LPIY+E ++E ++GKKRHE
Sbjct: 110 MAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHE 169
Query: 427 MPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNA 606
+PPH++A+ + AYRSMLQ+REDQSILCTGESGAGKTENTKKVIQYLAHVA + + +
Sbjct: 170 VPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGR---- 225
Query: 607 AAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGY 786
++P V GELE QLLQANPILEAFGN+KTVKNDNSSRFGKFIRINFD++GY
Sbjct: 226 -------KEPGVP---GELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGY 275
Query: 787 ISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRFLVNRGI 966
I GANIE YLLEKSR +RQA+DE SFHIFYQ+L G + K++ LLE +YRFL N
Sbjct: 276 IVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPS 335
Query: 967 TLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDD 1146
+ P + + F T+ S+R++GF+ +EI S++R+VSAVL GN+ +E+ +DQA + D+
Sbjct: 336 SSPG-QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDN 394
Query: 1147 RVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKW 1326
QK+C LLGL V + +A L PRIKVGR++V KAQ +EQA+FA+EA+AKA+YERLF+W
Sbjct: 395 TAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRW 454
Query: 1327 LVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILE 1506
LV R+N++LDR+ RQGASF+GILDIAGFEIF +NSFEQ+CINYTNEKLQQLFN+TMF+LE
Sbjct: 455 LVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLE 514
Query: 1507 QEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDEECLFPKANDKSFVEKLQK 1677
QEEYQREGI W F+DFGLDLQP IDLIE+P G+LALLDEEC FPKA DKSFVEK+ +
Sbjct: 515 QEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQ 574
Query: 1678 THNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFV 1854
HPKF P +R ++ F+V+HYAG+VDY A++WLMKNMDPLN+NV L+ STD
Sbjct: 575 EQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLT 634
Query: 1855 AGIWKDAEFAGICAAE----MNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHF 2022
A IWKD E GI E + + G R R+GMFRTV QL+KE L++LM TL NT+P F
Sbjct: 635 AEIWKDVE--GIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSF 692
Query: 2023 VRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDV 2202
VRCI+PNHEK++GK+ LVL+QLRCNGVLEGIRICRQGFPNR+ FQEFR RYEILTP+
Sbjct: 693 VRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNA 752
Query: 2203 IPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQA 2382
IPK F+DGK++ KMI AL++D NLYR+GQSK+FFR GVLA LEEERDLK+T +I++FQA
Sbjct: 753 IPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQA 812
Query: 2383 QCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIR 2562
RG+L+RR + N AYLKLR+WQWWRLFTKVKPLLQVTR D+ ++
Sbjct: 813 AARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQ 872
Query: 2563 AKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQT 2742
A+ EL+ +E + + E + ++ Q+ ERA + EQL+ E+E AE ++ RGRL
Sbjct: 873 ARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAA 932
Query: 2743 RNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTN 2922
R QELE +V+++ R+ +++ + +++ +K
Sbjct: 933 RKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVT 992
Query: 2923 VDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQ 3102
+ +D + L R++ + + Q
Sbjct: 993 TEAKMKKFEEDLLLLEDQNSKLSKSGSCWKIVWPSSHPRQLRRRRRSRASISYGSNMRPQ 1052
Query: 3103 LHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQ 3282
L +E + + ELE+ KR+L E + ++ + E+ + EEL QL +++EELQ
Sbjct: 1053 SQTWRDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAA 1112
Query: 3283 LTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDV 3462
L R ++E + K +R+ Q + E +ED+E+ER AR KAE RR++ +LE ++G++
Sbjct: 1113 LARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGEL 1172
Query: 3463 LDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQH 3642
D +D Q+L S++++EV K+ +E+ E ++E + + + + EL +Q+EQ
Sbjct: 1173 EDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQA 1232
Query: 3643 KKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHK 3822
++ + EK + + E +++ E++ LQ +R + +++R+ E L E+Q + + +
Sbjct: 1233 RRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERAR 1292
Query: 3823 RTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANI 4002
++L+R++ EL++++ E E + + L++ TR K+A
Sbjct: 1293 AEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALG 1352
Query: 4003 NRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVN--QQLEELRK 4176
+R R +E E L ++ EE R +E+ A+ E RR+ EE + EE R+
Sbjct: 1353 SRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARR 1412
Query: 4177 KNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFES 4356
+ R+ E L ++L E +R+ + ++++QQEL+D++M+LE R EK+Q+KF+
Sbjct: 1413 RAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQ 1472
Query: 4357 QMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQD 4536
+AEE+ AV +A+ +R+ E R+RE R LSL ++ +E EE +R R+L+ EL+
Sbjct: 1473 LLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEA 1532
Query: 4537 SISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSE 4716
+S+KDD GK+VHELE+A R E ND+R Q+ ELED L AEDA+LRLEVT QALK++
Sbjct: 1533 LLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQ 1592
Query: 4717 SDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEV 4896
+R + +D EE+RR L KQ+RD E E + E++ ++ AV+ RKK+E ++ EL+ Q+
Sbjct: 1593 HERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMAS 1652
Query: 4897 ANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREA 5076
A + KEE E E EE R ++E+I + RE++++ + +EAE +L+E
Sbjct: 1653 AGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1712
Query: 5077 NEGLMQARKQXXXXXXXXXXXRAKGG---GISSEEKRRLEAKIAQXXXXXXXXQSNCELA 5247
+AR+Q A G EEKR+LE ++ Q QSN EL
Sbjct: 1713 LAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELL 1772
Query: 5248 IDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQ 5427
D+ RK +Q+E +TT+LS ER+ + K E+ +Q LER ++ + ++ E ++GA++R +
Sbjct: 1773 NDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMT 1832
Query: 5428 MAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKS 5607
+AALE+K+ E+QL E +E+ + + RR EKRL + Q E+E+R +Q ++ LEK
Sbjct: 1833 IAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKG 1892
Query: 5608 NLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
NL+ + L+RQL+EAE+E SR + R +QRE +D+ ++ E + RE+
Sbjct: 1893 NLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREV 1938
>gi|39582082|emb|CAE63725.1| Hypothetical protein CBG08250
[Caenorhabditis briggsae]
Length = 2000
Score = 1598 bits (4137), Expect = 0.0
Identities = 853/1911 (44%), Positives = 1242/1911 (64%), Gaps = 11/1911 (0%)
Frame = +1
Query: 46 DPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDE--VLVELVDTSRQVTISRDDVQKAN 219
+P+ A WA++KL WVP + +GF +G++ + + + +EL++T + +S DD QK N
Sbjct: 22 NPSISADWAKKKLMWVPSEKDGFALGAVIGNPHPDGTIDIELMETGERQRVSSDDCQKPN 81
Query: 220 PPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIE 399
PPK++K EDMS LT LNEASVLHNLK RY+S+L YTYSGLFCVVINPYK++PIY++ + E
Sbjct: 82 PPKYEKCEDMSMLTCLNEASVLHNLKQRYFSNLYYTYSGLFCVVINPYKRIPIYTDSIAE 141
Query: 400 EFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAG 579
+FKGKKR EMPPH+FA+ + AYRSMLQER+DQSILCTGESGAGKTENTKKVIQYLA+VA
Sbjct: 142 QFKGKKRKEMPPHVFAVTEEAYRSMLQERDDQSILCTGESGAGKTENTKKVIQYLAYVAN 201
Query: 580 ATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFI 759
K+ + +I +G+LE QLLQANPILEAFGNSKTVKNDNSSRFGKFI
Sbjct: 202 RNMLKNRKTSTDLDI----STNRVMGQLEEQLLQANPILEAFGNSKTVKNDNSSRFGKFI 257
Query: 760 RINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLE-GVD 936
R++FD +G ISGANIEFYLLEKSRVLRQA +ERSFHIFYQ+L+G ++ ++LLE +
Sbjct: 258 RVHFDGTGCISGANIEFYLLEKSRVLRQAPNERSFHIFYQLLKGLPKSQRDQFLLEDSLS 317
Query: 937 NYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEK 1116
Y++L + L VDD E T+N+M IMG D+EI+ I+RVVSAV+L GNLEF+QE
Sbjct: 318 KYKYLTHGDSKLAGVDDGAEMKETLNAMSIMGLNDEEITGILRVVSAVMLFGNLEFSQEN 377
Query: 1117 KS-DQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAI 1293
K+ DQA L +D V QK+ LLG+ V EL +AFL+P+IKV R+ V+++Q+ +Q FAV AI
Sbjct: 378 KNNDQATLLNDAVAQKIAALLGVNVTELMRAFLKPKIKVQRDMVHRSQSVDQVNFAVGAI 437
Query: 1294 AKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQ 1473
AKASYERLF+WLV R+NKSL T RQ IG+LD+ GF F+ +SFEQ CIN TNE LQ
Sbjct: 438 AKASYERLFRWLVHRLNKSLGWT-RQQVKVIGLLDM-GFRNFETHSFEQWCINSTNENLQ 495
Query: 1474 QLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDK 1653
QLFNNTM I +Q+ Y EG+EW F+DFGL+LQPTIDLI+KPMG+++ LD+ CLFP+ ND+
Sbjct: 496 QLFNNTMVIRDQQ-YLDEGLEWKFVDFGLNLQPTIDLIDKPMGLMSTLDDVCLFPQGNDQ 554
Query: 1654 SFVEKLQKTHNKHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQ 1833
SFV++L TH++HPK++VP++RS+S FAVVHYAGRVDY A W +KNMDPLNENV+ +++
Sbjct: 555 SFVQRLNDTHSQHPKYVVPEIRSRSDFAVVHYAGRVDYQASGWRVKNMDPLNENVIDVLK 614
Query: 1834 NSTDPFVAGIWKD-AEFAGICAAEMNETA--FGMRS-RKGMFRTVSQLHKEQLTKLMTTL 2001
+ + + +WKD A+ + AA+ FG R +KGMFRTVSQL+KEQLT+LM+TL
Sbjct: 615 AAKESIILDMWKDIADVCSLSAADSGSDTGVFGSRMPKKGMFRTVSQLYKEQLTRLMSTL 674
Query: 2002 RNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRY 2181
NT+PHFVRCIIPNHEKK G +N++LVL+QLRCNGVLEGIRICRQGFP R+PF EFR RY
Sbjct: 675 NNTNPHFVRCIIPNHEKKHGVLNAHLVLDQLRCNGVLEGIRICRQGFPTRLPFHEFRQRY 734
Query: 2182 E-ILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLT 2358
E +L DVIP F+DGKE+VR++I L++D NL+RIGQSK+FFR GV+A EE RD KL+
Sbjct: 735 EKLLANDVIPAGFMDGKEAVRRIIQFLEVDDNLFRIGQSKIFFRAGVVAEFEEMRDQKLS 794
Query: 2359 ALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQV 2538
ALI +FQAQCRG+L RR+ NGLA+++LR WQWWRL TKVKPLL+V
Sbjct: 795 ALIESFQAQCRGWLGRRIMVRRREQEVAIKILQRNGLAWMRLREWQWWRLLTKVKPLLEV 854
Query: 2539 TRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELD 2718
T D+ I K+ ELR T ERL + E + +++++++ ER +++ +L ES AE+
Sbjct: 855 TNKDELIAEKEQELRVTSERLRRSEVFIADCKQQMEKIDEERILLKTRLDAESSERAEMF 914
Query: 2719 DIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXX 2898
+ R R+ R ELE +++D+ RL R+ E V+
Sbjct: 915 EERSRIAARKIELEGLLDDVSKRLEAEEQKAKKAEVETRRLTEMVKHLEENLEDEERSRQ 974
Query: 2899 XXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVK 3078
+K +++ +D+ + L+++L+D ERAK +K
Sbjct: 975 KLLLEKNSIESRLKELEAQGVELEDSGNKLTKEKKLLEERCEDLSSRLIDETERAKQLMK 1034
Query: 3079 AKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMK 3258
AK RLE + E +L +E+ + + E +R L + ++ EK K EEL QLM+
Sbjct: 1035 AKTRLEATIAETTDELEKEKHLRQQAENARRAADVLLREEQEACLEKTRKAEELTAQLMR 1094
Query: 3259 RDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQ 3438
++ EL + DEE A +++++R+++ D+ E++ E+ AR KAE RR++ +
Sbjct: 1095 KETELSQISMKNDEELAIRQQLEREIREIRAQCDDAVEELNKEKAARQKAEKARRDMAEE 1154
Query: 3439 LEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEE 3618
LE K ++ + D+ + L +++DEE +R +E T + +EE KA+ +++EE
Sbjct: 1155 LESYKAELEESNDKTNLQSQLKAKRDEEYAHLQRQLEDTLKTSDEAVEEIKAQSQKKIEE 1214
Query: 3619 LHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQAN 3798
L++ I+Q K+Q+ +K ++ A+ E ++ E++ + ++R D +KKRK EA LME
Sbjct: 1215 LNETIDQLKRQKISADKAKSSAESENENIRAELSNVASARQDAEKKRKTAEATLMEKDHK 1274
Query: 3799 LAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXX 3978
+ E + L+ +L + +EL+++ + + EE +N+ ++ A+
Sbjct: 1275 MREMQSNLEDLMAKLSKMNNELENIQKAKSAEETLNSNLLKKNASLDMQLSELTEASEED 1334
Query: 3979 TRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQ 4158
R K+ N+ RQLE++ ++ KE+A + ++KE + EA++K +E +
Sbjct: 1335 RRTKVNLNNKIRQLEEDLAIAIEAKEDALAAQEKIDKEARDLKLQLAEAKKKLDEENREV 1394
Query: 4159 LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKR 4338
+EE+RKK +++ +++ + +E A+++ ++KKK QE ED E ++ A+ R+ E++
Sbjct: 1395 MEEMRKKKEKELLAEKERADSAEQARDKAERAKKKALQEAEDVQKEYSDMMAATREMERK 1454
Query: 4339 QKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSL 4518
Q+K E Q+ +E+ A+ +RD Q +RD ET+ L L NE+ K+ +E ++ +R L
Sbjct: 1455 QRKHEQQLTDEKNNTLLAVQERDMAQQMIRDAETKALVLSNELSEKKDLIELLEKDKRML 1514
Query: 4519 QQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTN 4698
+ E+ + SNKDD GKNV+ELEK KR L+ ELN Q+ ELED LQIAEDAR R+EV
Sbjct: 1515 KLEIDNLASNKDDAGKNVYELEKTKRRLDEELNRAEQQIIELEDALQIAEDARSRVEVNM 1574
Query: 4699 QALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGEL 4878
QALK+E +R ++ ++ + E++++GL +IR+L ELE+E+R + AV+++KK E Q+ EL
Sbjct: 1575 QALKAEFERQLAAREEDEEDRKKGLAAKIRNLTEELESEQRSRQNAVANKKKFELQVSEL 1634
Query: 4879 EQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAER 5058
++ E A R E+ ++Q++ EAR A +D + R+A+++ RA E E
Sbjct: 1635 TEKNEAAFRQIEDLTRQLRKAQLSCKDFQLDASEARAALDDAVSAQRDAEKRARASEDEI 1694
Query: 5059 EQLREANEGLMQARKQXXXXXXXXXXXRA--KGGGISSEEKRRLEAKIAQXXXXXXXXQS 5232
++L + + ++++ A + S+EEKRRLEAK+ S
Sbjct: 1695 KRLMADVQAVTSSKRKAEAERDELIEEVATLRASSFSNEEKRRLEAKVVDLEDQLDEEVS 1754
Query: 5233 NCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQS 5412
ELA +K RKAQ QLEQ+T DL+MER++ ++ E+++ LER+NRD K ++ + E+ A +
Sbjct: 1755 ANELAQEKVRKAQQQLEQMTADLAMERSVCERNESDRIGLERANRDLKQQLLDAENTAVA 1814
Query: 5413 RARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKE 5592
R R Q+ EAKV LE QL VE Q+K R RR+E ++ + Q E+E+R +E ++
Sbjct: 1815 RLRTQINVAEAKVANLEQQLAVEEQDKMRQGRTLRRMETKMAEMQQMLEEERRQSETNRQ 1874
Query: 5593 LLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
E+ N + R LR QL++AE E R K +R ADD+ D NE LT+++
Sbjct: 1875 AAERQNTRIRQLRTQLEDAEAERDRLVKKVNEERRRADDVTDLNETLTKDV 1925
Score = 82.8 bits (203), Expect = 9e-14
Identities = 118/513 (23%), Positives = 220/513 (42%), Gaps = 51/513 (9%)
Frame = +1
Query: 4366 EERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSIS 4545
E+ VA++ +L R+ ++ +R RE + LL +V + E + D + +QEL+ +
Sbjct: 818 EQEVAIK--ILQRNGLAW-MRLREWQWWRLLTKVKPLLE-VTNKDELIAEKEQELRVTS- 872
Query: 4546 NKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDR 4725
E+ +RS E + D + QME++++ +I RL E + +A E
Sbjct: 873 ------------ERLRRS-EVFIADCKQQMEKIDEE-RILLKTRLDAESSERAEMFEERS 918
Query: 4726 AIS-------------NKDVEAEEKR--------RGLLKQIRDLENELENEKRGKSGAVS 4842
I+ +K +EAEE++ R L + ++ LE LE+E+R + +
Sbjct: 919 RIAARKIELEGLLDDVSKRLEAEEQKAKKAEVETRRLTEMVKHLEENLEDEERSRQKLLL 978
Query: 4843 HRKKIENQIGELEQQ----LEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQ---AKED 5001
+ IE+++ ELE Q + N+L +E E E A+Q AK
Sbjct: 979 EKNSIESRLKELEAQGVELEDSGNKLTKEKKLLEERCEDLSSRLIDETERAKQLMKAKTR 1038
Query: 5002 IAALLREADRKFRAVEAEREQ-LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKR 5178
+ A + E E E+E+ LR+ E +A + + + +
Sbjct: 1039 LEATIAETTD-----ELEKEKHLRQQAENARRAADVLLREEQEACLEKTRKAEELTAQLM 1093
Query: 5179 RLEAKIAQXXXXXXXXQSNCELAIDKQ-----RKAQVQLEQITTDLSMERTLNQKTEAEK 5343
R E +++Q +++ ELAI +Q R+ + Q + +L+ E+ QK E +
Sbjct: 1094 RKETELSQISM-----KNDEELAIRQQLEREIREIRAQCDDAVEELNKEKAARQKAEKAR 1148
Query: 5344 QSLERSNRDYKAKITEL--ESGAQSRARAQMAALEAKVQ-YLEDQLNVEGQEKTAANRAA 5514
+ + YKA++ E ++ QS+ +A+ A +Q LED L + +
Sbjct: 1149 RDMAEELESYKAELEESNDKTNLQSQLKAKRDEEYAHLQRQLEDTLKTSDEAVEEIKAQS 1208
Query: 5515 RRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDE--------------AE 5652
++ + LN+T Q + +K + ++AK E +N N+R +L AE
Sbjct: 1209 QKKIEELNETIDQLKRQKISADKAKSSAES---ENENIRAELSNVASARQDAEKKRKTAE 1265
Query: 5653 DEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
+ + K R +Q +DL+ ++ EL N
Sbjct: 1266 ATLMEKDHKMREMQSNLEDLMAKLSKMNNELEN 1298
>gi|34868040|ref|XP_239866.2| similar to myosin [Rattus norvegicus]
Length = 1916
Score = 1576 bits (4081), Expect = 0.0
Identities = 867/1931 (44%), Positives = 1226/1931 (62%), Gaps = 18/1931 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
D ++L V + + P A W +KL WVP + +GF SIK E DEV+VELV+ ++V
Sbjct: 10 DEKFLFVDKNFINSPMAQADWVAKKLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKV 69
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
T+ +DD+QK NPPKF K+EDM+ELT LNEASVLHNL++RY+S LIYTYSGLFCVV+NPYK
Sbjct: 70 TVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYK 129
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
LPIYSE +++ +KGKKRHEMPPHI+AIADTAYRSMLQ+REDQSILCTGESGAGKTENTK
Sbjct: 130 HLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTK 189
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVIQYLA VA + + K ++ GELE QLLQANPILEAFGN+KTVK
Sbjct: 190 KVIQYLAVVASSHKGKKDSSIT--------------GELEKQLLQANPILEAFGNAKTVK 235
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
NDNSSRFGKFIRINFD++GYI LLEKSR +RQA+DER+FHIFY ++ G K
Sbjct: 236 NDNSSRFGKFIRINFDVTGYIVD------LLEKSRAIRQARDERTFHIFYYLIAGAKEKM 289
Query: 907 KSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLL 1086
+++ LLE ++Y FL N + +P D + F T+ +M IMGF+++E +I++VVS+VL
Sbjct: 290 RNDLLLESFNSYTFLSNGFVPIPAAQDDEMFQETLEAMSIMGFSEEEQLAILKVVSSVLQ 349
Query: 1087 LGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQE 1266
LGN+ F +E+ +DQA + D+ QKVCHL+G+ V + +A L PRIKVGR+ V KAQ +E
Sbjct: 350 LGNIVFKKERNTDQASMPDNTAAQKVCHLVGINVTDFTRAILTPRIKVGRDVVQKAQTKE 409
Query: 1267 QAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQIC 1446
QA+FA+EA+AKA+YERLF+W+++R+NK+LD+THRQGASF+GILDIAGFEIF++NSFEQ+C
Sbjct: 410 QADFAIEALAKATYERLFRWILSRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLC 469
Query: 1447 INYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALL 1617
INYTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP I+LIE+P GVLALL
Sbjct: 470 INYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALL 529
Query: 1618 DEECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKN 1794
DEEC FPKA DKSFVEKL HPKF P ++ K+ F+++HYAG+VDY+A WL KN
Sbjct: 530 DEECWFPKATDKSFVEKLCSEQGNHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKN 589
Query: 1795 MDPLNENVVGLMQNSTDPFVAGIWKDAE-FAGICA-AEMNETAF--GMRSRKGMFRTVSQ 1962
MDPLN+NV L+ S+D FVA +WKD + G+ A+M E++ +++KGMFRTV Q
Sbjct: 590 MDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQ 649
Query: 1963 LHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGF 2142
L+KEQL KLMTTLRNT+P+FVRCIIPNHEK+SGK+++ LVLEQLRCNGVLEGIRICRQGF
Sbjct: 650 LYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGF 709
Query: 2143 PNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVL 2322
PNR+ FQEFR RYEIL + IPK F+DGK++ MI AL++D NLYRIGQSK+FFRTGVL
Sbjct: 710 PNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVL 769
Query: 2323 AHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWW 2502
AHLEEERDLK+T +IM FQA CRG+L+R+ +T N AYLKLRNWQWW
Sbjct: 770 AHLEEERDLKITDVIMAFQAMCRGYLARKAFTKRQQQLTAMKVIQRNCAAYLKLRNWQWW 829
Query: 2503 RLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQ 2682
RLFTKVKPLLQVTR ++E++AK++E++ KER K E + +E E++ Q+ E+ ++QEQ
Sbjct: 830 RLFTKVKPLLQVTRQEEEMQAKEEEMQKIKERQQKAESELKELEQRHTQLAEEKTLLQEQ 889
Query: 2683 LQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDX 2862
LQ E+E AE +++R RL + QELE I+++M RL R+K + +
Sbjct: 890 LQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRSQQLQAERKKMAQQMLKE 949
Query: 2863 XXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQL 3042
D ++ + A
Sbjct: 950 EKSRQELEKLKRKLEGDASDFHEQIADL--------QAQIAELKMQLAKKEEELQAALAR 1001
Query: 3043 LDHEERAKHGVKAKGR-LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEK 3219
LD E K+ K R LE + +L++DL+ ER +++ E+ KR L ELE K L +
Sbjct: 1002 LDEEITQKNNALKKIRELEGHVSDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDT 1061
Query: 3220 MGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQT-TIDELREDMETERNA 3396
+ KR++E+ DEE+ + ++MR T ++EL E +E + A
Sbjct: 1062 LDSTATQQELRAKREQEVTMLKKALDEETRSHEAQVQEMRQKHTQAVEELTEQLEQFKRA 1121
Query: 3397 RNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK 3576
+ + +++ LEK D+ ++ + K+ +E + +EG+
Sbjct: 1122 KANLDKSKQ----TLEKENADLAGEL--------------RVLGQAKQEVEHKKKKLEGQ 1163
Query: 3577 IEEQKAKFS---RQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADI 3747
++E ++K S R EL D++ + + + + N+A+ + +A+E+A L
Sbjct: 1164 LQELQSKCSDGERARTELSDKVHKLQNEVESVTGMLNEAEGKAIKLAKEVASL------- 1216
Query: 3748 DKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRL 3927
+ L + Q L E K + +L + DE + L +EE A N++R +
Sbjct: 1217 -------GSQLQDTQELLQEETRQKLNVSTKLRQLEDERNSLQDQLDEEMEAKQNLERHV 1269
Query: 3928 ATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAAR 4107
+T +++ + LLD + + H+
Sbjct: 1270 STLNIQGPYGSPLGLCGLFVQLFPL------------LLDFLSWRKSVHF---SGFHSWP 1314
Query: 4108 QGAGEARRKAEE--SVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELE 4281
++++K ++ S + +EE +K+ +++E L +Q EE A +++ ++K ++QQEL+
Sbjct: 1315 LQLSDSKKKLQDLASTIEVMEEGKKRLQKEMEGLGQQYEEKAAAYDKLEKTKNRLQQELD 1374
Query: 4282 DSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLN 4461
D ++L+N R + EK+QKKF+ +AEE+ K +RD E R++ET+ LSL
Sbjct: 1375 DLVVDLDNQRQLVSNLEKKQKKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLAR 1434
Query: 4462 EVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE 4641
++ E EE +R + L+ E++D +S+KDD GKNVHELEK+KR+LE ++ +MR Q+EE
Sbjct: 1435 ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMRTQLEE 1494
Query: 4642 LEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKR 4821
LED LQ EDA+LRLEV QALK + +R + +D + EEKRR L +Q+ + E ELE+E++
Sbjct: 1495 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERK 1554
Query: 4822 GKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKED 5001
++ A + +KK+E + +LE Q + A + +EE ++Q E ++AR ++++
Sbjct: 1555 QRALAAAAKKKLEGDLKDLELQADSAVKGREEAIKQLRKLQAQMKDFQRELDDARASRDE 1614
Query: 5002 IAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRA---KGGGISSEE 5172
I A +E ++K +++EAE QL+E +ARKQ A G +E
Sbjct: 1615 IFATSKENEKKAKSLEAELMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNTLQDE 1674
Query: 5173 KRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSL 5352
KRRLEA+IAQ Q N E D+ RKA +Q EQ++ +L ER+ QK E+ +Q L
Sbjct: 1675 KRRLEARIAQLEEELEEEQGNMEAMSDRVRKATLQAEQLSNELVTERSAAQKNESARQQL 1734
Query: 5353 ERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKR 5532
ER N++ ++K+ E+E +++ ++ +AALEAK+ LE+Q+ E +EK AA + ++ +K+
Sbjct: 1735 ERQNKELRSKLQEVEGAVKAKLKSTVAALEAKIVQLEEQIEQEAREKQAATKLLKQKDKK 1794
Query: 5533 LNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
L + Q EDE++ EQ KE EK N K + L+RQL+EAE+E R R +QRE D+
Sbjct: 1795 LKEVLLQVEDERKMVEQYKEQAEKGNTKVKQLKRQLEEAEEESQRINANRRKLQRELDEA 1854
Query: 5713 LDANEQLTREL 5745
++NE + RE+
Sbjct: 1855 TESNEAMGREV 1865
Score = 107 bits (267), Expect = 3e-21
Identities = 122/553 (22%), Positives = 245/553 (44%), Gaps = 26/553 (4%)
Frame = +1
Query: 3028 LTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELED---S 3198
++++ D +RA+ + K E + L + L + K ELE+ + L AE+ED S
Sbjct: 1407 ISSKYADERDRAEAEAREK---ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSS 1463
Query: 3199 KDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDM 3378
KD + + + ++E+ L + QM +M+T ++EL +++
Sbjct: 1464 KDDVGKNVHELEKSKRAL------------------------ETQMEEMRTQLEELEDEL 1499
Query: 3379 ETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQ 3558
+ +A+ + E+ + + Q E+ DL +R DE+ +R +++
Sbjct: 1500 QATEDAKLRLEVNMQALKGQFER----------------DLQAR-DEQNEEKRRQLQRQL 1542
Query: 3559 HTMEGKIEEQ----------KAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMA 3708
H E ++E++ K K +++L Q + K R + KQ + + D
Sbjct: 1543 HEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAVKGREEAIKQLRKLQAQMKDFQ 1602
Query: 3709 QEIALLQASRADI-------DKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELD 3867
+E+ +ASR +I +KK K EA LM++Q +LA ++ ++ Q + ++EL
Sbjct: 1603 RELDDARASRDEIFATSKENEKKAKSLEAELMQLQEDLAAAERARK----QADLEKEELA 1658
Query: 3868 HLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEK---NA 4038
+ + +RRL +IA + +LE+E+ A
Sbjct: 1659 EELASSLSGRNTLQDEKRRL------------------EARIAQLE--EELEEEQGNMEA 1698
Query: 4039 LLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLE 4218
+ D +A L E+ + A + A + + +Q +ELR K L++VE K
Sbjct: 1699 MSDRVRKATLQAEQLSNEL-VTERSAAQKNESARQQLERQNKELRSK-LQEVEGAVKAKL 1756
Query: 4219 ESEVA--KERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKA 4392
+S VA + +I+Q +++I+QE + + ++ +K+ K+ Q+ +ER V++
Sbjct: 1757 KSTVAALEAKIVQLEEQIEQEAREKQAATKLLK----QKDKKLKEVLLQVEDERKMVEQ- 1811
Query: 4393 LLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNV 4572
++ T+V L +++ +E + + RR LQ+EL ++ + + G+ V
Sbjct: 1812 ------YKEQAEKGNTKVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREV 1865
Query: 4573 HELE-KAKRSLEA 4608
+ L+ K +R EA
Sbjct: 1866 NALKSKLRRGNEA 1878
Score = 75.5 bits (184), Expect = 1e-11
Identities = 104/602 (17%), Positives = 232/602 (38%), Gaps = 13/602 (2%)
Frame = +1
Query: 2551 DEIRAKDDELRATKERLLKMEHDF---RENEKKLDQVIVERAVIQEQLQQESEN-SAELD 2718
+E A D+L TK RL + D +N+++L + ++ +QL E +N S++
Sbjct: 1353 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQKKFDQLLAEEKNISSKYA 1412
Query: 2719 DIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXX 2898
D R R + +E E + L + + D
Sbjct: 1413 DERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVH 1472
Query: 2899 XXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQL-LDHEERAKHGV 3075
K ++ +D L Q D + R +
Sbjct: 1473 ELEKSKRALETQMEEMRTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNE 1532
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELED-------SKDHLAEKMGKVE 3234
+ + +L+ QLHE E +L ER+ ++ K+KL +L+D + E + ++
Sbjct: 1533 EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAVKGREEAIKQLR 1592
Query: 3235 ELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEM 3414
+L Q+ EL DE A +K+ + ++ + +L+ED+ AR +A++
Sbjct: 1593 KLQAQMKDFQRELDDARASRDEIFATSKENEKKAKSLEAELMQLQEDLAAAERARKQADL 1652
Query: 3415 TRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKA 3594
+ E+ +L + LQD R + + + +E+ Q ME + ++
Sbjct: 1653 EKEELAEEL-------ASSLSGRNTLQDEKRRLEARIAQLEEELEEEQGNMEA-MSDRVR 1704
Query: 3595 KFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQ-ASRADIDKKRKIHE 3771
K + Q E+L +++ + + E + Q +++ ++ ++ ++ A +A + E
Sbjct: 1705 KATLQAEQLSNELVTERSAAQKNESARQQLERQNKELRSKLQEVEGAVKAKLKSTVAALE 1764
Query: 3772 AHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXX 3951
A +++++ + + K+ L++ +L + ++ E+E + A
Sbjct: 1765 AKIVQLEEQIEQEAREKQAATKLLKQKDKKLKEV-LLQVEDERKMVEQYKEQA------- 1816
Query: 3952 XXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARR 4131
T++K RQLE+ + +E + R L++E+ A +
Sbjct: 1817 -----EKGNTKVK----QLKRQLEEAE----EESQRINANRRKLQRELDEATE------- 1856
Query: 4132 KAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVR 4311
+ E++ +++ L+ K R E + R++++ ++E++ + +
Sbjct: 1857 -SNEAMGREVNALKSKLRRGNE--ASFVPSRRAGGRRVIENTDGSEEEMDARDSDFNGTK 1913
Query: 4312 AS 4317
AS
Sbjct: 1914 AS 1915
Score = 66.6 bits (161), Expect = 7e-09
Identities = 84/446 (18%), Positives = 169/446 (37%), Gaps = 1/446 (0%)
Frame = +1
Query: 4417 QELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKR 4596
Q++++R+ + S L E++ L E + LQ++LQ + + L K+
Sbjct: 856 QKIKERQQKAESELKELEQRHTQLAEEKTL---LQEQLQAETELYAEAEEMRVRLAAKKQ 912
Query: 4597 SLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLL 4776
LE L++M ++EE ED Q + R ++ Q LK E R E E+ +R L
Sbjct: 913 ELEEILHEMEARLEEEEDRSQQLQAERKKM--AQQMLKEEKSRQ------ELEKLKRKLE 964
Query: 4777 KQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXX 4956
D ++ + ++ QI EL+ QL + +EE
Sbjct: 965 GDASDFHEQIAD--------------LQAQIAELKMQLA---KKEEELQAALARLDEEIT 1007
Query: 4957 EYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXX 5136
+ ++ R+ + ++ L + D + A +Q R+ E L + +
Sbjct: 1008 QKNNALKKIRELEGHVSDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTAT 1067
Query: 5137 XRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQ-LEQITTDLSMER 5313
+ E + + E ++ + E + + R+ Q +E++T L +
Sbjct: 1068 QQ--------ELRAKREQEVTMLKKALDEETRSHEAQVQEMRQKHTQAVEELTEQLEQFK 1119
Query: 5314 TLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEK 5493
+ KQ+LE+ N D L +L V GQ K
Sbjct: 1120 RAKANLDKSKQTLEKENAD-----------------------------LAGELRVLGQAK 1150
Query: 5494 TAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRER 5673
++LE +L + + D +RA + + + K + ++ L+EAE + +
Sbjct: 1151 QEVEHKKKKLEGQLQELQSKCSDGERARTELSDKVHKLQNEVESVTGMLNEAEGKAIKLA 1210
Query: 5674 TKHRNVQREADDLLDANEQLTRELMN 5751
+ ++ + D + ++ TR+ +N
Sbjct: 1211 KEVASLGSQLQDTQELLQEETRQKLN 1236
>gi|47223930|emb|CAG06107.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 1966
Score = 1570 bits (4064), Expect = 0.0
Identities = 875/2017 (43%), Positives = 1238/2017 (60%), Gaps = 106/2017 (5%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
++L R+ V +P A WA +KL WVP + GF GS+K E DE VEL+D+ ++V +
Sbjct: 2 KFLYGDRSGVNNPLAQADWASKKLVWVPSEKLGFEPGSLKEEHGDECTVELMDSGKKVKV 61
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF+K+EDM+ELT LNEASVLHNLKDRYYS LIYTYSGLFCVV+NPYK L
Sbjct: 62 NKDDIQKMNPPKFNKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVVNPYKHL 121
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYSED++ +KGKKRHEMPPHI+AI DTAYRSM+Q+REDQSILCTGESGAGKTENTKKV
Sbjct: 122 PIYSEDIVNMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKV 181
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
IQYLA +A + ++K ++ GELE QLLQANPILEAFGN+KTVKND
Sbjct: 182 IQYLAFIASSHKSKK----------EQGSTGFSHGELEKQLLQANPILEAFGNAKTVKND 231
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFY---------------LLEKSRVLRQAQDERSFH 867
NSSRFGKFIRINFD++GYI GANIE Y LLEKSR +RQA++ERSFH
Sbjct: 232 NSSRFGKFIRINFDVNGYIVGANIETYFPEPDKPARWPRATNLLEKSRAIRQAKEERSFH 291
Query: 868 IFYQILRGCSAKEKSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDE 1047
IFY +L G K +SE LE YRFL N +T+P + D F T+ + +IM +++E
Sbjct: 292 IFYYLLTGAGDKLRSELCLEDYSKYRFLSNGNMTIPGLQDKDLFAETMEAFQIMSISEEE 351
Query: 1048 ISSIMRVVSAVL--LLGNLEFTQEKKSDQAM-------------LQDDRVI--------- 1155
+ +R + + L T+ SD+ LQ+ +
Sbjct: 352 RAGTVRAFLGFIGVVEPGLGLTRPGSSDRVPEGGVSRAPAGEHDLQEGAALGPGLHARRH 411
Query: 1156 ----QKVCHLLGLPVIELQKAFLRPRIKV------------------------------- 1230
QKVCHLLG+ V E +A L PRIKV
Sbjct: 412 RYAAQKVCHLLGINVTEFTRAILSPRIKVCVPNIGKKNLNNQLLATFLRTAKGFHAIPTL 471
Query: 1231 ---------------GREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTH 1365
GR++V KAQ QEQAEFAVEA+AKASYER+F+ LV RINK+LD+T
Sbjct: 472 VPQLEFLLVFISPQVGRDYVQKAQTQEQAEFAVEALAKASYERMFRCLVFRINKALDKTK 531
Query: 1366 RQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDF 1545
RQGASFIGILDIAGFEIF++ CINYTNEKLQQLFN+TMFILEQEEYQREGIEW F
Sbjct: 532 RQGASFIGILDIAGFEIFEL------CINYTNEKLQQLFNHTMFILEQEEYQREGIEWSF 585
Query: 1546 IDFGLDLQPTIDLIEKPMG---VLALLDEECLFPKANDKSFVEKLQKTHNKHPKFIVPD- 1713
IDFGLDLQP IDLI+KP G +LALLDEEC FPKA DKSFVEK+ + HPKF P
Sbjct: 586 IDFGLDLQPCIDLIDKPAGPPGILALLDEECWFPKATDKSFVEKVIQEQGTHPKFQKPKK 645
Query: 1714 MRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWKDAE-FAGI 1890
++ + F V+HYAG+VDY AD+WLMKNMDPLNE+V L+ STD F+A +W+D + G+
Sbjct: 646 LKDDADFCVIHYAGKVDYKADEWLMKNMDPLNESVATLLNQSTDKFIADLWRDMDRIVGL 705
Query: 1891 C-AAEMNETAFG-MRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGK 2064
A M+++++G +++KGMFRTV QL+KEQL LMTTLRNT+P+FVRCIIPNHEKK+ K
Sbjct: 706 DKVAGMSDSSYGAFKTKKGMFRTVGQLYKEQLANLMTTLRNTNPNFVRCIIPNHEKKASK 765
Query: 2065 INSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRK 2244
+ +LVL+QLRCNGVLEGIRICRQGFPNR+ FQEFR RYEILTP+ IPK F+DGK++
Sbjct: 766 LEPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKGFMDGKQACVL 825
Query: 2245 MITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXX 2424
MI AL++D NLYRIGQSKVFFR GVLAHLEEERD+K+T +I++FQA CRG+++R+ +
Sbjct: 826 MIRALELDQNLYRIGQSKVFFRAGVLAHLEEERDMKITDVIISFQAWCRGYVARKTFAKR 885
Query: 2425 XXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLL 2604
N AYLKLRNWQWWRLFTKVKPLLQVTR ++E+ AK+DEL KER
Sbjct: 886 QQQQTAMRVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMLAKEDELSKVKERQE 945
Query: 2605 KMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRD 2784
+ E +E E K Q+ E+ +QEQLQ E+E AE +++R RL R QELE I++DM
Sbjct: 946 QAEKMLKEYESKQQQLAAEKMALQEQLQAETELCAEAEELRARLVNRKQELEEILHDMES 1005
Query: 2785 RLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXX 2964
RL R+K + + D +K D
Sbjct: 1006 RLEEEEERANQLHIERKKMQQNIADLEQQLDEEEAARQKLQIEKVTTD------------ 1053
Query: 2965 XQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQY 3144
+++ +HEER LE+Q ++L + + +R+
Sbjct: 1054 -----------------------SKIKEHEERIL-------MLEDQNNKLNKTASGKRR- 1082
Query: 3145 KSELEQHKRKLLAELEDSKDHLAEKMGKVEELNN----QLMKRDEELQHQLTRYDEESAN 3312
+ + R+ +A S + + QL K++EELQ L R D+ SA+
Sbjct: 1083 --KCAKSWRRTVANWRASPRTSTTRSQTCRPRSQICAAQLAKKEEELQDALNRLDKSSAD 1140
Query: 3313 VTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATML 3492
T QK+ R+++ I EL ED+ E R ++ +++ +LE +K ++LD +D +
Sbjct: 1141 NTAAQKKNRELEAHILELEEDLARECGYRAQSTQRCKDLEEELEALKTELLDTLDSTAVQ 1200
Query: 3493 QDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQ 3672
Q+L ++++ EV K+A E+ + E ++ E K + + EL++Q+EQ K+ + +EK
Sbjct: 1201 QELRTKRETEVAQLKKAGEEEKKMHEAQLAELSKKHFQTLNELNEQLEQTKRNKMSVEKA 1260
Query: 3673 QNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERS 3852
+ + E ++ E+ + ++D + +RK E+ + E+Q E++ K+ ++++ +
Sbjct: 1261 KQALESEFNELQTEMRTVNQRKSDTEHRRKKAESQVQELQVRCDETERQKQEALEKVAKL 1320
Query: 3853 RDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEK 4032
+ ELD++N + E + L++ TR K++ R +Q+EDE+
Sbjct: 1321 QSELDNVNAIVNALEGKCTKSSKDLSSVESHLQDTQELLQEETRQKLSLSTRLKQMEDEQ 1380
Query: 4033 NALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESV--NQQLEELRKKNLRDVEHLQ 4206
L + EE E + +EK+I E ++K E+ + EE RK+ + + L+
Sbjct: 1381 TGLQEMLEEEEEAKRTVEKQISTLNAQLSEMKKKVEQEALSLEAAEEDRKRLKSESDALR 1440
Query: 4207 KQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQ 4386
QLEE E A E++ ++K ++QQEL+D + ++ R + EK+Q+KF+ +AEE+
Sbjct: 1441 LQLEEKEAAYEKLEKTKTRLQQELDDLLVNQDSQRQLVNNMEKKQRKFDQMLAEEKAISN 1500
Query: 4387 KALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGK 4566
+ +RD + R++ETR L+L E++ +++H ++ + R L+ E++D IS+KDD GK
Sbjct: 1501 QRADERDRAEADAREKETRALTLSRELEDLRDHKKDLEEANRLLKAEMEDLISSKDDAGK 1560
Query: 4567 NVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDV 4746
NVHELE++KR++E +L +M+ Q+EELED LQ EDA+LRLEV QA+K++ DR + +D
Sbjct: 1561 NVHELERSKRAMEQQLAEMKTQLEELEDELQATEDAKLRLEVNMQAMKAQFDRDLQARDE 1620
Query: 4747 EAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXX 4926
+ EE+R+ L+KQ+ + E ELE+E+R +S AVS +KK+E +GELE + AN+ +EE
Sbjct: 1621 QGEERRKQLVKQVHEFEAELEDERRQRSQAVSAKKKLELDLGELEAHINDANKGREEALK 1680
Query: 4927 XXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAE----REQLREANEGLMQ 5094
+ EC+E R ++++ +E +RK +++EAE +E L A+ Q
Sbjct: 1681 QLKKLQAQFKDLARECDELRLSRDEALNCSKETERKLKSMEAETLQFQEDLASADRLKRQ 1740
Query: 5095 ARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQV 5274
+ + AK I E+KRRL+ +IAQ Q N E++ ++ ++A
Sbjct: 1741 IQTERDELQDEVKDGNAK-NSILQEDKRRLDDQIAQLKEELEEEQLNTEMSNERYKRAAQ 1799
Query: 5275 QLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQ 5454
Q +Q+ +L+ ER+ +Q+ E + ER N++ K+ ELES +S+ ++ +++LEAKV
Sbjct: 1800 QCDQLNAELTSERSHSQQLEGARSQAERKNKELSLKLQELESTIKSKYKSSISSLEAKVA 1859
Query: 5455 YLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRR 5634
LE+QL+ E +E+ A+R RR EK+L + Q EDE+R +EQ K+ +K N + R L+R
Sbjct: 1860 QLEEQLDAEIRERQQASRTVRRSEKKLKELLIQVEDERRNSEQYKDQADKLNSRMRQLKR 1919
Query: 5635 QLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
QL+EAE+E++R R +QRE DD + + + RE+
Sbjct: 1920 QLEEAEEEVTRANAYRRKLQRELDDASETADAMNREV 1956
Score = 114 bits (286), Expect = 2e-23
Identities = 134/680 (19%), Positives = 263/680 (37%), Gaps = 30/680 (4%)
Frame = +1
Query: 2539 TRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELD 2718
T++ ++ + + L+ T+E L + +L Q+ E+ +QE L++E E ++
Sbjct: 1339 TKSSKDLSSVESHLQDTQELLQEETRQKLSLSTRLKQMEDEQTGLQEMLEEEEEAKRTVE 1398
Query: 2719 DIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXX 2898
++ T N +L ++M+ ++ R++
Sbjct: 1399 K---QISTLNAQL----SEMKKKVEQEALSLEAAEEDRKRLKSESDALRLQLEEKEAAYE 1451
Query: 2899 XXXXDKTNVDQXXXXXXXXXXXXQDAY---DXXXXXXXXXXXXXXGLTTQLLDHEERAKH 3069
KT + Q + + ++ Q D +RA+
Sbjct: 1452 KLEKTKTRLQQELDDLLVNQDSQRQLVNNMEKKQRKFDQMLAEEKAISNQRADERDRAEA 1511
Query: 3070 GVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELED---SKDHLAEKMGKVEEL 3240
+ K E + L ++L R +K +LE+ R L AE+ED SKD + +
Sbjct: 1512 DAREK---ETRALTLSRELEDLRDHKKDLEEANRLLKAEMEDLISSKDDAGKNV------ 1562
Query: 3241 NNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTR 3420
H+L R + M++Q+ +M+T ++EL ++++ +A+ + E+
Sbjct: 1563 ------------HELER------SKRAMEQQLAEMKTQLEELEDELQATEDAKLRLEVNM 1604
Query: 3421 REVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKF 3600
+ + AQ ++ DL +R ++ K+ ++Q+ H E ++E+++ +
Sbjct: 1605 QAMKAQFDR----------------DLQARDEQGEERRKQLVKQV-HEFEAELEDERRQR 1647
Query: 3601 SRQVE----------ELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASR---- 3738
S+ V EL I K R + KQ + + D+A+E L+ SR
Sbjct: 1648 SQAVSAKKKLELDLGELEAHINDANKGREEALKQLKKLQAQFKDLARECDELRLSRDEAL 1707
Query: 3739 ---ADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFA 3909
+ ++K K EA ++ Q +LA +D KR Q++ RDEL + +
Sbjct: 1708 NCSKETERKLKSMEAETLQFQEDLASADRLKR----QIQTERDELQDEVKDGNAKNSILQ 1763
Query: 3910 NMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALL----DEKEEAEGLRA 4077
+RRL T + RA Q D+ NA L ++ EG R+
Sbjct: 1764 EDKRRLDDQIAQLKEELEEEQLNTEMSNERYKRAAQQCDQLNAELTSERSHSQQLEGARS 1823
Query: 4078 HLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSK 4257
E++ E + + L K + E L ++ E + A + +S+
Sbjct: 1824 QAERKNKELSLKLQELESTIKSKYKSSISSLEAKVAQLEEQLDAEIRERQQASRTVRRSE 1883
Query: 4258 KKIQQ---ELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELR 4428
KK+++ ++ED E + R ++ + Q+ E V +A R + +EL
Sbjct: 1884 KKLKELLIQVEDERRNSEQYKDQADKLNSRMRQLKRQLEEAEEEVTRANAYRRKLQRELD 1943
Query: 4429 DRETRVLSLLNEVDIMKEHL 4488
D ++ EV +K L
Sbjct: 1944 DASETADAMNREVSTLKSKL 1963
>gi|47221621|emb|CAF97886.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 2113
Score = 1508 bits (3904), Expect = 0.0
Identities = 876/2119 (41%), Positives = 1216/2119 (57%), Gaps = 221/2119 (10%)
Frame = +1
Query: 52 ATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKF 231
A+ A WA ++L WVP + GF SI+ E DEV VEL D+ R+VT+SR++VQ+ NPP+F
Sbjct: 3 ASQADWAAKRLVWVPSEKHGFESASIREERGDEVEVELTDSQRRVTLSREEVQRMNPPRF 62
Query: 232 DKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKG 411
K+EDM++LT LNEASVLHNL++RYYS LIYTYSGLFCVV+NPYK LPIY+E ++E ++G
Sbjct: 63 SKVEDMADLTCLNEASVLHNLRERYYSGLIYTYSGLFCVVVNPYKNLPIYTESIVEMYRG 122
Query: 412 KKRHEMPPHIFAIADTAYRSMLQ--------------------EREDQSILCTGESGAGK 531
KKR EMPPHI+AI++ AYRSMLQ REDQSILCTGESGAGK
Sbjct: 123 KKRQEMPPHIYAISEAAYRSMLQGYSPLSLTSYPQPGPTPELAHREDQSILCTGESGAGK 182
Query: 532 TENTKKVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGN 711
TENTKKVIQYLAHVA + + P R GELE QLLQANPILEAFGN
Sbjct: 183 TENTKKVIQYLAHVASSHK-------------AHPKPRVSQGELEKQLLQANPILEAFGN 229
Query: 712 SKTVKNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRG 891
+KTVKNDNSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFYQ+L G
Sbjct: 230 AKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDERTFHIFYQMLCG 289
Query: 892 CSAKEKSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDE-------- 1047
S + K E LL VD YRFL I +P D + F T++SM IMGF +E
Sbjct: 290 TSEELKEELLLGSVDEYRFLTCGSIPVPGQSDSENFTQTMDSMAIMGFTPEENICKRVKS 349
Query: 1048 -----ISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFL 1212
S+++V+SAVL GN+ F +EK DQA + D+ QK+CHLLG+ V+E +A L
Sbjct: 350 RAVCSSVSMLKVISAVLQFGNISFLKEKHHDQASMPDNTAAQKLCHLLGINVLEFTRAIL 409
Query: 1213 RPRIKVGREFVNKAQNQE----------------------------QAEFAVEAIAKASY 1308
PRIKVGRE+V KAQ +E QA+FAVEA+AKA+Y
Sbjct: 410 TPRIKVGREYVQKAQTKEQVRSEAPGCVCVSVCVQGSVAAVCSFLLQADFAVEALAKATY 469
Query: 1309 ERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNN 1488
ERLF+WLV RIN++LDR RQGASFIGILDIAGFEIF +NSFEQ+CINYTNEKLQQLFN+
Sbjct: 470 ERLFRWLVHRINRALDRRQRQGASFIGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNH 529
Query: 1489 TMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEK---PMGVLALLDEECLFPKANDKSF 1659
TMFILEQEEYQREGIEW+FIDFGLDLQP IDLIEK P GVLALLDEEC FP+A D+SF
Sbjct: 530 TMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKSAHPPGVLALLDEECWFPRATDRSF 589
Query: 1660 VEKLQKTHNKHPKFI-VPDMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQN 1836
VEKL HPKF R ++ F+++HYAG+VDY AD WL+KNMDPLN+NV L+
Sbjct: 590 VEKLSAEQGSHPKFFRSKQPRGEADFSIIHYAGKVDYKADDWLVKNMDPLNDNVASLLHQ 649
Query: 1837 STDPFVAGIWK-------------------------------DAEFAGICAAEMNETAFG 1923
S+D FV+ +WK D +G + + A G
Sbjct: 650 SSDHFVSELWKEDIQTLPRVYFFDSYATLQANGSDMDRIVGLDQVSSGDSSGPVTFGAAG 709
Query: 1924 MRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCN 2103
++++KGMFRTV QL+KE LTKLM TLRNT+P+F+RCIIPNHEK++GK+ +LVL+QLRCN
Sbjct: 710 LKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFLRCIIPNHEKRAGKLAPHLVLDQLRCN 769
Query: 2104 GVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYR 2283
GVLEGIRICRQGFPNR+PFQEFR RYEILTP+ IP+ F+DGK++ MI AL++D NL+R
Sbjct: 770 GVLEGIRICRQGFPNRIPFQEFRQRYEILTPNAIPRTFMDGKQASELMIKALELDHNLFR 829
Query: 2284 IGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXN 2463
+GQSKVFFR GVLAHLEEERDLK+T I+ FQ+ RG+L+R+ + N
Sbjct: 830 VGQSKVFFRAGVLAHLEEERDLKITDTIIRFQSISRGYLARKAFMKRQQQLSALRVMQRN 889
Query: 2464 GLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKL 2643
AYLKLRNWQWWRLFTKVKPLLQVTR D+EI+A++ +L KE L ++E +F E E+K
Sbjct: 890 CAAYLKLRNWQWWRLFTKVKPLLQVTRQDEEIQARESQLLKAKENLNQVEQNFTELERKH 949
Query: 2644 DQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXX 2823
Q++ E+AV+ +QLQ E+E AE +++R RL +R QELE +++++ RL
Sbjct: 950 VQLLEEKAVLADQLQTEAELLAEAEEMRARLASRKQELEEVISELETRLEEEEERSLQQN 1009
Query: 2824 XXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXX 3003
++K + V+D +K ++ + D
Sbjct: 1010 TEKKKLQQIVQDLEEQLEEEESSRQRLLLEKVTLETKVKSLETEMMNAVEQKDRLCKEKK 1069
Query: 3004 XXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLA 3183
+T QL + EE+AK K K + E + +LE+ L RE Q + E E+ KRK+
Sbjct: 1070 NIEERLSEVTDQLTEEEEKAKSLNKLKNKQEAIIADLEERLKREEQCRLEQEKWKRKMEN 1129
Query: 3184 ELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDE 3363
E D++D L++ + +L L ++++E+ +R E A + ++ + + E
Sbjct: 1130 EAVDAQDQLSDLGMMLADLKGSLAQKEKEIATLQSRKKEPLAQKP--SGRFKEALSQVSE 1187
Query: 3364 LREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVN----- 3528
L E++E ER ++++ E +R++ +LE ++ ++ D +D Q+L S E N
Sbjct: 1188 LTEEVENERLSKDRIEKQKRDLSEELEALRTELEDTLDTTAAQQELRSVTQREENQSDWE 1247
Query: 3529 ATKRAIEQIQHTMEGK--------------------IEEQKAKFSRQVEELHDQIEQHKK 3648
K + EG+ E + K S V+ L +Q++ K+
Sbjct: 1248 GNKHEALSPETEPEGRRSCTSCRGAWRRRRGATRRSCSEMRLKHSAAVDGLQEQLDNSKR 1307
Query: 3649 QRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRT 3828
R LEK + ++ER ++ E+ LQA R + ++ RK E+ L E+ A L+++D +
Sbjct: 1308 ARQSLEKAKATLEEERQNLTSELKSLQAGRMESERGRKRAESQLQELSARLSQADREREE 1367
Query: 3829 LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINR 4008
+++++ + E++ ++ E + + + TR K+ R
Sbjct: 1368 REERVQKLQSEIETMSGSLSSFETKSLRFSKEVNSLESQLNDAKETLQDETRQKMTLATR 1427
Query: 4009 ARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQ-------------------------- 4110
R LE+EKN L++ EE E L ++I Q
Sbjct: 1428 VRALEEEKNGLMERLEEEEERSKELTRQIQTHSQQVIWRPPPSRRKRSRSQPAHGCLPAA 1487
Query: 4111 -------GAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKK-- 4263
G G+ RR Q+ E R R + E A E + +
Sbjct: 1488 GRAPQAVGGGQQRRGERRGGAQEAPE-RAGRRRGEGAAEGGGEGQGGAAEGAAEGGDRGH 1546
Query: 4264 ------IQQELEDSSMELENVRAS----HRDSEKRQKKF----------ESQMAEERVAV 4383
+ EL E E VR R S Q F Q E AV
Sbjct: 1547 DAGPAAGEAELHSPGEEAEEVRPGLDRLARPSHTGQVLFVTTESFCPLLHPQCLAEEKAV 1606
Query: 4384 QKALL-DRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDF 4560
L +RD + R++ET+ L+L + +++ EE +RV + L+ E++ ++ +DD
Sbjct: 1607 STRLAEERDRAEADSREKETKYLALSRALQDVQDQKEELERVNKQLRLEMEQLVNQQDDV 1666
Query: 4561 GKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNK 4740
GKNVHELE+ +R+LE E ++RVQ +ELE+ L AE++RLRLEVT QALK++ +R IS
Sbjct: 1667 GKNVHELERTRRALETEAQNLRVQTQELEEELSEAENSRLRLEVTLQALKAQFEREISTA 1726
Query: 4741 DVEAEEKRRGLLKQ----------------------------IRDLENELENEKRGKSGA 4836
+ + EEKRR L KQ +R+LE +LE E+ +S A
Sbjct: 1727 EEKGEEKRRALSKQVGWEAAAGVLLLLHLSRSVTANLPFERKVRELEIQLEEERSQRSQA 1786
Query: 4837 VSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALL 5016
+ +K+++ ++ E E QLE A+R KEE E E ++ + A+++I A
Sbjct: 1787 TASKKQLDAELQESETQLESASRGKEEAMKQLRRLQGQMKEILRELDDTKLARDEIIAQS 1846
Query: 5017 READRKFRAVEAEREQLRE----------------ANEGLMQARKQXXXXXXXXXXXRAK 5148
++ ++K + +EAE E +E + +Q
Sbjct: 1847 KDNEKKIQTLEAEVLHFSEGWGGPDRLHVCAQELAVSERQRRQAQQERDEMADEMVNSTS 1906
Query: 5149 GGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQK 5328
G EEKRRLE +++Q QSN EL ++ RKA +Q+E +T L ERTL QK
Sbjct: 1907 GKTALCEEKRRLETRVSQLEEALEEEQSNSELMSERLRKATLQMETLTVQLQGERTLVQK 1966
Query: 5329 TEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANR 5508
EA + LE+ N++ K ++++LE + + + +AALEAK+ +E+QL E QE+ AN+
Sbjct: 1967 AEAARDHLEKQNKELKTRLSDLEGAVRGKHKLSVAALEAKIDSMEEQLEQERQERAIANK 2026
Query: 5509 AARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRN 5688
R+ EK+L + Q EDE+R +Q +E L+KS + + L+R L+E E+E SR + R
Sbjct: 2027 LVRKAEKKLKEALMQAEDERRHADQYREQLDKSMGRLKQLKRHLEEVEEENSRSNAQRRK 2086
Query: 5689 VQREADDLLDANEQLTREL 5745
+QRE ++L D+ + +TRE+
Sbjct: 2087 LQRELEELTDSGQSMTREI 2105
>gi|34856033|ref|XP_218617.2| similar to nonmuscle myosin heavy chain
[Rattus norvegicus]
Length = 2087
Score = 1493 bits (3865), Expect = 0.0
Identities = 824/1987 (41%), Positives = 1218/1987 (60%), Gaps = 94/1987 (4%)
Frame = +1
Query: 67 WAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIED 246
W R++ WVP + GF +++ E +E VEL ++ R++ + RD +Q+ NPPKF K ED
Sbjct: 46 WTARRMVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAED 105
Query: 247 MSELTYLNEASVLHNLKDRYYSSLIY---------------------------------- 324
M+ELT LNEASVLHNL++RYYS LIY
Sbjct: 106 MAELTCLNEASVLHNLRERYYSGLIYLGLAEAGNTVVQTSAMLQGLNNDEFSVSHINLGQ 165
Query: 325 ---TYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQ 495
TYSGLFCVVINPYK+LPIY+E ++E ++GKKRHE+PPHI+A+ + AYRSMLQ+REDQ
Sbjct: 166 PYQTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHIYAVTEGAYRSMLQDREDQ 225
Query: 496 SILCTGESGAGKTENTKKV---IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELE 666
SILCTGESGAGKTENTKKV + ++A + + ++ ++Q + G +
Sbjct: 226 SILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPGELERQLLQANPILEAFGNAK 285
Query: 667 H-----------------------QLLQANPILEAFG----------NSKTVKNDNSSRF 747
+++ + +L G + +NSSR
Sbjct: 286 TVKNDNSSRFGKFIRINFDIAGYIPVVRLSSVLYGVGGMGVQGDSGEDGSGKARENSSRK 345
Query: 748 GKFIRINFD-MSGY----ISGANIEFY---LLEKSRVLRQAQDERSFHIFYQILRGCSAK 903
+ + +SG+ I F LLEKSR +RQA+DE SFHIFYQ+L G +
Sbjct: 346 SRQRELQGSVLSGWGNPTACWVPISFSRNDLLEKSRAIRQAKDECSFHIFYQLLGGAGEQ 405
Query: 904 EKSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVL 1083
K++ LLE +YRFL N + P + + F T+ S+R++G +EI++++R VSAVL
Sbjct: 406 LKADLLLEPYSHYRFLTNGPSSSPG-QERELFQETLESLRVLGLLPEEITAMLRTVSAVL 464
Query: 1084 LLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQ 1263
GN+ +E+ +DQA + D+ QK+C LLGL V + +A L PRIKVGR++V KAQ +
Sbjct: 465 QFGNIVLKKERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTK 524
Query: 1264 EQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQI 1443
EQA+FA+EA+AKA+YERLF+WLV R+N++LDR+ RQGASF+GILDIAGFEIF +NSFEQ+
Sbjct: 525 EQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQL 584
Query: 1444 CINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLAL 1614
CINYTNEKLQQLFN+TMF+LEQEEYQREGI W F+DFGLDLQP IDLIE+P G+LAL
Sbjct: 585 CINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLAL 644
Query: 1615 LDEECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMK 1791
LDEEC FPKA DKSFVEK+ + HPKF P ++R ++ F+V+HYAG+VDY A++WLMK
Sbjct: 645 LDEECWFPKATDKSFVEKVAQEQGSHPKFQRPRNLRDQADFSVLHYAGKVDYKANEWLMK 704
Query: 1792 NMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAE----MNETAFGMRSRKGMFRTVS 1959
NMDPLN+NV L+ STD A IWKD E GI E + + G R R+GMFRTV
Sbjct: 705 NMDPLNDNVAALLHQSTDRLTAEIWKDVE--GIVGLEQVSSLGDGPPGGRPRRGMFRTVG 762
Query: 1960 QLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQG 2139
QL+KE L++LM TL NT+P FVRCI+PNHEK++GK+ LVL+QLRCNGVLEGIRICRQG
Sbjct: 763 QLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQG 822
Query: 2140 FPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGV 2319
FPNR+ FQEFR RYEILTP+ IPK F+DGK++ KMI AL++D NLYR+GQSK+FFR GV
Sbjct: 823 FPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGV 882
Query: 2320 LAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQW 2499
LA LEEERDLK+T +I++FQA RG+L+RR + N AYLKLRNWQW
Sbjct: 883 LAQLEEERDLKVTDIIVSFQAAARGYLARRAFQRRQQQQSALRVMQRNCAAYLKLRNWQW 942
Query: 2500 WRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQE 2679
WRLF KVKPLLQVTR D+ ++A+ EL+ +E + + E + ++ Q+ ERA + E
Sbjct: 943 WRLFIKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAE 1002
Query: 2680 QLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRD 2859
QL+ E+E +E ++ R RL R QELE +V ++ R+ +++ + +++
Sbjct: 1003 QLRAEAELCSEAEETRARLAARKQELELVVTELEARVGEEEECSRQLQSEKKRLQQHIQE 1062
Query: 2860 XXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQ 3039
+K + +D ++Q
Sbjct: 1063 LETHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERRLLEERLAEFSSQ 1122
Query: 3040 LLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEK 3219
+ EE+ K K + + E + ++E L +E + + ELE+ KR+L E + ++ + E+
Sbjct: 1123 AAEEEEKVKSLNKLRVKYEATIADMEDRLKKEEKGRQELEKLKRRLDGESSELQEQMMEQ 1182
Query: 3220 MGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNAR 3399
+ EEL QL +++EELQ L R +EE + K +R+ Q + E +ED+E ER AR
Sbjct: 1183 KQRAEELLIQLGRKEEELQSALVRAEEEGGARAQLLKSLREAQAGLAEAQEDLEAERVAR 1242
Query: 3400 NKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKI 3579
KAE RR++ +LE ++G++ D +D Q+L S++++EV K+ +E+ T E +
Sbjct: 1243 AKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEEARTHEVAM 1302
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKR 3759
+E + + S+ + EL +Q+EQ ++ +S EK + + E +++ E++ LQ SR + ++KR
Sbjct: 1303 QELRQRHSQALVELTEQLEQARRGKSVWEKTRLSLEAEVSELKTELSSLQTSRQEGEQKR 1362
Query: 3760 KIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAX 3939
+ E+ L E+Q ++S+ + ++L+R++ EL+ ++ E E + + L++A
Sbjct: 1363 RRLESQLQEVQGRSSDSERARAEAAEKLQRAQVELESVSTALSEAESKAIRLSKELSSAE 1422
Query: 3940 XXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAG 4119
TR K+A +R R LE E L ++ EE R +E+ +
Sbjct: 1423 SQLHDTQELLQEETRAKLALGSRVRALEAEAAGLREQMEEEVVARERAGRELQTTQAQLS 1482
Query: 4120 EARRKAEE--SVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSM 4293
E RR+ EE +V + EE R++ R+ E L ++L E A ER+ ++++++QQEL+D+++
Sbjct: 1483 EWRRRQEEEAAVLEAGEEARRRAAREAETLAQRLAEKTEAVERLERARRRLQQELDDATV 1542
Query: 4294 ELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDI 4473
+L + EK+Q+KF+ +AEE+ AV +A+ DR+ + E R+RE R LSL ++
Sbjct: 1543 DLGQQKQLLSTLEKKQRKFDQLLAEEKAAVLRAVEDRERVEAEGREREARALSLTRALEE 1602
Query: 4474 MKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDN 4653
+E EE +R R+L+ EL+ +S+KDD GKNVHELE+A+R E +D+R Q+ ELED
Sbjct: 1603 EQEAREELERQNRALRAELEALLSSKDDVGKNVHELERARRVAEQAASDLRTQVTELEDE 1662
Query: 4654 LQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSG 4833
L AEDA+LRLEVT QALK++ +R + +D EE+RR L KQ+RD E E + E++ ++
Sbjct: 1663 LTAAEDAKLRLEVTVQALKAQHERDLQGRDDAGEERRRQLAKQLRDAEVERDEERKQRAL 1722
Query: 4834 AVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAAL 5013
A++ RKK+E ++ EL+ Q A + KEE E E EE R ++E++ L
Sbjct: 1723 AMAARKKLELELEELKAQTSAAGQGKEEAVKQLKKMQAQMKELWREVEETRSSREEMFTL 1782
Query: 5014 LREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGG---GISSEEKRRL 5184
RE++++ + +EAE +L+E +AR+Q A G + EEKR+L
Sbjct: 1783 SRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMAEEVASGNLSKAATLEEKRQL 1842
Query: 5185 EAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSN 5364
E ++ Q Q+N EL D RK +Q+E +TT+LS ER+ + K E+ +Q LER
Sbjct: 1843 EGRLGQLEEELEEEQNNSELLKDHYRKLVLQVETLTTELSAERSFSAKAESGRQQLERQI 1902
Query: 5365 RDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDT 5544
++ +A++ E ++GA++R + +AALE+K+ E+QL E +E+ + + RR EKRL +
Sbjct: 1903 QELRARLGEEDAGARARQKMLIAALESKLAQAEEQLEQESRERILSGKLVRRAEKRLKEV 1962
Query: 5545 TQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDAN 5724
Q ++E+R +Q ++ LEKSNL+ + L+RQL+EAE+E SR + R +QRE +D+ ++
Sbjct: 1963 VLQVDEERRVADQLRDQLEKSNLRLKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESA 2022
Query: 5725 EQLTREL 5745
E + RE+
Sbjct: 2023 ESMNREV 2029
Score = 42.4 bits (98), Expect = 0.14
Identities = 35/205 (17%), Positives = 94/205 (45%), Gaps = 12/205 (5%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGK--------VEELN 3243
+L Q+ L +L+ ER + ++ E +++L ++++ + L E+ + L
Sbjct: 1869 KLVLQVETLTTELSAERSFSAKAESGRQQLERQIQELRARLGEEDAGARARQKMLIAALE 1928
Query: 3244 NQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRR 3423
++L + +E+L+ + V +K+++++ +DE R + R+ K+ + +
Sbjct: 1929 SKLAQAEEQLEQESRERILSGKLVRRAEKRLKEVVLQVDEERRVADQLRDQLEKSNLRLK 1988
Query: 3424 EVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFS 3603
++ QLE+ + ++ A + + R+ E+V + ++ + T+ ++ F+
Sbjct: 1989 QLKRQLEEAE----EEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFT 2044
Query: 3604 ----RQVEELHDQIEQHKKQRSQLE 3666
RQV L + + +++ E
Sbjct: 2045 TRTVRQVFRLEEGVASDEEEAEGAE 2069
>gi|29436380|gb|AAH49849.1| MYH9 protein [Homo sapiens]
Length = 1374
Score = 1389 bits (3596), Expect = 0.0
Identities = 708/1382 (51%), Positives = 947/1382 (68%), Gaps = 8/1382 (0%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL V + + +P A WA +KL WVP GF S+K E +E +VELV+ ++V +
Sbjct: 8 KYLYVDKNFINNPLAQADWAAKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKV 67
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDM+ELT LNEASVLHNLK+RYYS LIYTYSGLFCVVINPYK L
Sbjct: 68 NKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNL 127
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYSE+++E +KGKKRHEMPPHI+AI DTAYRSM+Q+REDQSILCTGESGAGKTENTKKV
Sbjct: 128 PIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKV 187
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
IQYLA+VA + ++K GELE QLLQANPILEAFGN+KTVKND
Sbjct: 188 IQYLAYVASSHKSKKDQ-----------------GELERQLLQANPILEAFGNAKTVKND 230
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA++ER+FHIFY +L G K+
Sbjct: 231 NSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKT 290
Query: 913 EYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 1092
+ LLE + YRFL N +T+P D F T+ +MRIMG ++E ++RV+S VL LG
Sbjct: 291 DLLLEPYNKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLG 350
Query: 1093 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA 1272
N+ F +E+ +DQA + D+ QKV HLLG+ V + + L PRIKVGR++V KAQ +EQA
Sbjct: 351 NIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQA 410
Query: 1273 EFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICIN 1452
+FA+EA+AKA+YER+F+WLV RINK+LD+T RQGASFIGILDIAGFEIFD+NSFEQ+CIN
Sbjct: 411 DFAIEALAKATYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCIN 470
Query: 1453 YTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDE 1623
YTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP IDLIEKP G+LALLDE
Sbjct: 471 YTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDE 530
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMD 1800
EC FPKA DKSFVEK+ + HPKF P ++ K+ F ++HYAG+VDY AD+WLMKNMD
Sbjct: 531 ECWFPKATDKSFVEKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMD 590
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQLH 1968
PLN+N+ L+ S+D FV+ +WKD + G+ A M+ETA ++RKGMFRTV QL+
Sbjct: 591 PLNDNIATLLHQSSDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLY 650
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
KEQL KLM TLRNT+P+FVRCIIPNHEKK+GK++ +LVL+QLRCNGVLEGIRICRQGFPN
Sbjct: 651 KEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPN 710
Query: 2149 RVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAH 2328
RV FQEFR RYEILTP+ IPK F+DGK++ MI AL++D+NLYRIGQSKVFFR GVLAH
Sbjct: 711 RVVFQEFRQRYEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAH 770
Query: 2329 LEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRL 2508
LEEERDLK+T +I+ FQA CRG+L+R+ + N AYLKLRNWQWWRL
Sbjct: 771 LEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRL 830
Query: 2509 FTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQ 2688
FTKVKPLLQV+R ++E+ AK++EL +E+ L E+ E E Q++ E+ +QEQLQ
Sbjct: 831 FTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQ 890
Query: 2689 QESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXX 2868
E+E AE +++R RL + QELE I +D+ R+ ++K + +++
Sbjct: 891 AETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEE 950
Query: 2869 XXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLD 3048
+K + +D TT L +
Sbjct: 951 QLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTE 1010
Query: 3049 HEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGK 3228
EE++K K K + E + +LE+ L RE + + ELE+ +RKL + D D +AE +
Sbjct: 1011 EEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQ 1070
Query: 3229 VEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKA 3408
+ EL QL K++EELQ L R +EE+A + K++R++++ I EL+ED+E+ER +RNKA
Sbjct: 1071 IAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKA 1130
Query: 3409 EMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQ 3588
E +R++ +LE +K ++ D +D Q+L S++++EVN K+ +E+ T E +I+E
Sbjct: 1131 EKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEM 1190
Query: 3589 KAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIH 3768
+ K S+ VEEL +Q+EQ K+ ++ LEK + + ER ++A E+ +L + D + KRK
Sbjct: 1191 RQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKV 1250
Query: 3769 EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXX 3948
EA L E+Q E + + L D++ + + ELD++ + + + + + + +
Sbjct: 1251 EAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQL 1310
Query: 3949 XXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEAR 4128
R K++ + +Q+EDEKN+ ++ EE E + +LEK+I + +
Sbjct: 1311 QDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMK 1370
Query: 4129 RK 4134
+K
Sbjct: 1371 KK 1372
Score = 139 bits (349), Expect = 1e-30
Identities = 129/554 (23%), Positives = 258/554 (46%), Gaps = 20/554 (3%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYK-------SELEQHKRKLLAE---LEDSKDHLAEKMGKVEE 3237
R E ++ E++L + R+ + +E+E + +L+AE L++ E + EE
Sbjct: 842 RQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEE 901
Query: 3238 LNNQLMKRDEELQ---HQL-TRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNK 3405
L +L + +EL+ H L R +EE +Q + + MQ I EL E +E E +AR K
Sbjct: 902 LRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQK 961
Query: 3406 AEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEE 3585
++ + A+L+K++ +E +L+D + +E + I + + + E+
Sbjct: 962 LQLEKVTTEAKLKKLE-------EEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEK 1014
Query: 3586 QKA------KFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADI 3747
K+ K + +L +++ + +KQR +LEK + + + + D++ +IA LQA A++
Sbjct: 1015 SKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAEL 1074
Query: 3748 DKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRL 3927
+ E E+QA LA +E L++ R+ ++ ++E+ E A+ +
Sbjct: 1075 KMQLAKKEE---ELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNK-- 1129
Query: 3928 ATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAAR 4107
+ K L+ E LD + LR+ E+E++ +
Sbjct: 1130 ----------------AEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILK 1173
Query: 4108 QGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDS 4287
+ E + E Q++E+R+K+ + VE L +QLE+++ K + ++K+ ++ E +
Sbjct: 1174 KTLEEEAKTHEA----QIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGEL 1229
Query: 4288 SMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEV 4467
+ E++ + DSE ++KK E+Q+ E +V + + + EL D+ T+ L E+
Sbjct: 1230 ANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEG----ERVRTELADKVTK---LQVEL 1282
Query: 4468 DIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELE 4647
D + L +SD L ++ S D + + E + K SL +L + +
Sbjct: 1283 DNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR 1342
Query: 4648 DNLQIAEDARLRLE 4689
+ L+ E+A+ LE
Sbjct: 1343 EQLEEEEEAKHNLE 1356
Score = 112 bits (281), Expect = 8e-23
Identities = 127/532 (23%), Positives = 233/532 (42%), Gaps = 13/532 (2%)
Frame = +1
Query: 4015 QLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAG--EARRKAEESVNQQLEELRKKNLR 4188
QL+++ A + EAE LRA L + + EAR + EE Q L+ +KK +
Sbjct: 884 QLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQ 943
Query: 4189 DVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAE 4368
+++ L++QLEE E A++++ K + +L+ +LE + D + K E ++ E
Sbjct: 944 NIQELEEQLEEEESARQKLQLEKVTTEAKLK----KLEEEQIILEDQNCKLAK-EKKLLE 998
Query: 4369 ERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISN 4548
+R+A L + ++ + L N+ + M LEE R+RR +Q
Sbjct: 999 DRIAEFTTNLTEE------EEKSKSLAKLKNKHEAMITDLEE--RLRREEKQR------- 1043
Query: 4549 KDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRA 4728
ELEK +R LE + D+ Q+ EL+ A+ A L++++ + + E A
Sbjct: 1044 --------QELEKTRRKLEGDSTDLSDQIAELQ-----AQIAELKMQLAKK--EEELQAA 1088
Query: 4729 ISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRL 4908
++ + EA +K L K+IR+LE+++ + + R K E Q +L ++LE
Sbjct: 1089 LARVEEEAAQKNMAL-KKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTE 1147
Query: 4909 KEEYXXXXXXXXXXXXEYQIECEEARQAKEDIA----ALLREADRKF-RAVEAEREQLRE 5073
E+ + + E ++ E+ A A ++E +K +AVE EQL +
Sbjct: 1148 LEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQ 1207
Query: 5074 AN--EGLMQARKQXXXXXXXXXXXRAK----GGGISSEEKRRLEAKIAQXXXXXXXXQSN 5235
+ ++ KQ K G G S +++++EA++ + +
Sbjct: 1208 TKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERV 1267
Query: 5236 CELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSR 5415
DK K QV+L+ +T LS + + K + +LE +D + + E
Sbjct: 1268 RTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQE-------- 1319
Query: 5416 ARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKR 5571
Q +L K++ +ED+ N ++ A LEK++ Q D K+
Sbjct: 1320 ENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKK 1371
Score = 102 bits (253), Expect = 1e-19
Identities = 110/558 (19%), Positives = 240/558 (42%), Gaps = 23/558 (4%)
Frame = +1
Query: 3502 MSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSR--QVEELHDQIEQHKKQRSQLEKQQ 3675
+SR++EE+ A + + +++ E+Q A +R ++E L Q+ K Q ++Q
Sbjct: 840 VSRQEEEMMAKEEELVKVR-------EKQLAAENRLTEMETLQSQLMAEKLQL----QEQ 888
Query: 3676 NQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSR 3855
QA+ E A+E+ RA + K++ E +++A + E +E + L + ++ +
Sbjct: 889 LQAETELCAEAEEL------RARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQ 942
Query: 3856 DELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKN 4035
+ L EEEE A +Q K+ + ++LE+E+
Sbjct: 943 QNIQELEEQLEEEESARQKLQLE---------------------KVTTEAKLKKLEEEQI 981
Query: 4036 ALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQL 4215
L D+ + EK++ R EE ++ L +L+ K+ + L+++L
Sbjct: 982 ILEDQN-----CKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERL 1036
Query: 4216 EESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKAL 4395
E ++ + ++++K++ + D S ++ ++A + + + K E ++ V++
Sbjct: 1037 RREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEA 1096
Query: 4396 LDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVH 4575
++ +++R+ E+++ L ++ ES+R R+
Sbjct: 1097 AQKNMALKKIRELESQISELQEDL--------ESERASRN-------------------- 1128
Query: 4576 ELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAE 4755
+ EK KR L EL ++ ++E+ D+ ++ R + E LK + + + +
Sbjct: 1129 KAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQ 1188
Query: 4756 EKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXX 4935
E R+ + + +L +LE KR K+ ++ +EN+ GEL +++V + K +
Sbjct: 1189 EMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRK 1248
Query: 4936 XXXXXXXEYQIECEEARQAKEDIA--------------ALLREADRK-------FRAVEA 5052
E Q++ E + + ++A LL ++D K F A+E+
Sbjct: 1249 KVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALES 1308
Query: 5053 EREQLREANEGLMQARKQ 5106
QL++ E L + +Q
Sbjct: 1309 ---QLQDTQELLQEENRQ 1323
Score = 92.4 bits (228), Expect = 1e-16
Identities = 124/586 (21%), Positives = 236/586 (40%), Gaps = 50/586 (8%)
Frame = +1
Query: 4066 GLRAHLEKE---------IHAARQGAGEARRKAEESVNQQLEELR--KKNLRDVEHLQKQ 4212
G+ AHLE+E I G RKA QQL ++ ++N L+
Sbjct: 766 GVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNW 825
Query: 4213 LEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFE---SQMAEERVAV 4383
K + L + ++E+ EL VR +E R + E SQ+ E++ +
Sbjct: 826 QWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQL 885
Query: 4384 QKAL---LDRDAMSQELRDRETRVLSLLNEV-DIMKEHLEESDRVRRSLQQELQDSISNK 4551
Q+ L + A ++ELR R T L E+ ++ +EE + + LQ E + N
Sbjct: 886 QEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNI 945
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAI 4731
+ + + E E A++ L+ E ++++LE+ I ED +L + L+
Sbjct: 946 QELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFT 1005
Query: 4732 SNKDVEAEEKRRGLLK-------QIRDLENELENEKRGKSGAVSHRKKIE-------NQI 4869
+N E EEK + L K I DLE L E++ + R+K+E +QI
Sbjct: 1006 TNL-TEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQI 1064
Query: 4870 GELEQQL-EVANRL---KEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKF 5037
EL+ Q+ E+ +L +EE + + ++ R+ + I+ L + + +
Sbjct: 1065 AELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESER 1124
Query: 5038 RAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXX 5217
+ +Q R+ E L + + + KR E I +
Sbjct: 1125 ASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ------ELRSKREQEVNILKKTLEE 1178
Query: 5218 XXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELE 5397
++ +Q+ +Q +E++ L + + E KQ+LE + ++ L
Sbjct: 1179 EAKTHEAQIQEMRQKHSQA-VEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLL 1237
Query: 5398 SGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTT---------- 5547
G + + + +EA++Q L+ + N + +T +L+ L++ T
Sbjct: 1238 QG-KGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKS 1296
Query: 5548 ----QQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRER 5673
+ F + + +ELL++ N + +L +L + EDE + R
Sbjct: 1297 SKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR 1342
Score = 52.8 bits (125), Expect = 1e-04
Identities = 60/306 (19%), Positives = 124/306 (39%), Gaps = 9/306 (2%)
Frame = +1
Query: 4852 KIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADR 5031
K E + E+QL NRL E +++ +E QA+ ++ A E
Sbjct: 850 KEEELVKVREKQLAAENRLTEMETLQSQLMAE-----KLQLQEQLQAETELCAEAEELRA 904
Query: 5032 KFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXX 5211
+ A + E E++ E ++ ++ EK++++ I +
Sbjct: 905 RLTAKKQELEEICHDLEARVEEEEERCQHLQA--------------EKKKMQQNIQELEE 950
Query: 5212 XXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERT---------LNQKTEAEKQSLERSN 5364
+L ++ + ++QLE++TT+ +++ N K EK+ LE
Sbjct: 951 ---------QLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRI 1001
Query: 5365 RDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDT 5544
++ +TE E ++S A+ + EA + LE++L E +++ + R+LE D
Sbjct: 1002 AEFTTNLTEEEEKSKSLAKLKNKH-EAMITDLEERLRREEKQRQELEKTRRKLEGDSTDL 1060
Query: 5545 TQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDAN 5724
+ Q + + + K L K K L+ L E+E +++ + ++ + +
Sbjct: 1061 SDQIAELQAQIAELKMQLAK---KEEELQAALARVEEEAAQKNMALKKIRELESQISELQ 1117
Query: 5725 EQLTRE 5742
E L E
Sbjct: 1118 EDLESE 1123
>gi|49117916|gb|AAH72844.1| Unknown (protein for IMAGE:4971062)
[Xenopus laevis]
Length = 1388
Score = 1374 bits (3557), Expect = 0.0
Identities = 708/1383 (51%), Positives = 946/1383 (68%), Gaps = 9/1383 (0%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
QYL V R + AT A W ++ WVP + GF SIK + +EV+VEL + ++V +
Sbjct: 12 QYLFVDRNPTSGTATQADWTAKRQVWVPSEKHGFEAASIKEDRGEEVIVELAENGKRVPV 71
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDM+ELT LNEASVLHNLKDRYYS LIYTYSGLFCVVINPYK L
Sbjct: 72 AKDDIQKMNPPKFTKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNL 131
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIY+E ++E ++GKKRHE+PPHI+AI++TAYRSMLQ+REDQSILCTGESGAGKTENTKKV
Sbjct: 132 PIYTEQIVEMYRGKKRHEIPPHIYAISETAYRSMLQDREDQSILCTGESGAGKTENTKKV 191
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPI-GELEHQLLQANPILEAFGNSKTVKN 729
IQYLAHVA + + + + A P N GELEHQLLQANPILEAFGN+KTVKN
Sbjct: 192 IQYLAHVASSHKGRKEHTA--------PSSSNTFYGELEHQLLQANPILEAFGNAKTVKN 243
Query: 730 DNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEK 909
DNSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FH+FYQ+L G K
Sbjct: 244 DNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAVRQAKDERTFHVFYQLLAGAGEHVK 303
Query: 910 SEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLL 1089
++ LLE + YRFL N + + D F T+ SM+IMGF +EI S++++VSAVL
Sbjct: 304 TDLLLEPFNQYRFLSNGNLPITGQQDRDIFQETMESMKIMGFNHEEIMSLLKMVSAVLQF 363
Query: 1090 GNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQ 1269
GN+ F +E+ +DQA + D+ QK+CHLLGL V E +A L PRIKVGR++V KAQ +EQ
Sbjct: 364 GNIIFRKERNTDQASMPDNTAAQKLCHLLGLNVTEFTRAILMPRIKVGRDYVQKAQTKEQ 423
Query: 1270 AEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICI 1449
A+FAVEA+AKA YERLF+WLV RINK+LDRT RQGASFIGILDIAGFEIF++NSFEQ+CI
Sbjct: 424 ADFAVEALAKALYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCI 483
Query: 1450 NYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLD 1620
NYTNEKLQQLFN+TMF+LEQEEYQREGIEW+FIDFGLDLQP IDLIE+P GVL+LLD
Sbjct: 484 NYTNEKLQQLFNHTMFVLEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLSLLD 543
Query: 1621 EECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNM 1797
EEC FPKA DKSFVEK+ + HPKF P +R K+ ++HYAG+VDY AD+WLMKNM
Sbjct: 544 EECWFPKATDKSFVEKVIQELGTHPKFQKPRQLRDKADLCIIHYAGKVDYKADEWLMKNM 603
Query: 1798 DPLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAFG--MRSRKGMFRTVSQL 1965
DPLN+NV L+ STD F A +WKD + G+ + M E +FG +++KGMFRTV QL
Sbjct: 604 DPLNDNVATLLHQSTDKFTAELWKDVDRIVGLDQVSGMGEMSFGSSYKTKKGMFRTVGQL 663
Query: 1966 HKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFP 2145
+KE L+KLM+TLRNT+P+FVRCIIPNHEKK+GK+ +LVL+QLRCNGVLEGIRICRQGFP
Sbjct: 664 YKESLSKLMSTLRNTNPNFVRCIIPNHEKKAGKLEPHLVLDQLRCNGVLEGIRICRQGFP 723
Query: 2146 NRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLA 2325
NR+ FQEFR RYEILTP+ IPK F+DGK++ MI AL++D NLYRIGQSK+FFR GVLA
Sbjct: 724 NRIVFQEFRQRYEILTPNAIPKGFMDGKQACAIMIKALELDPNLYRIGQSKIFFRAGVLA 783
Query: 2326 HLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWR 2505
HLEEERDLK+T +I+ FQA RG+L+RR + N AYLKLR+WQWWR
Sbjct: 784 HLEEERDLKITDIIVFFQAAARGYLARRAFFKKQHQMSALKVVQRNCAAYLKLRHWQWWR 843
Query: 2506 LFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQL 2685
LFTKVKPLLQVTR D+ ++AK EL+ K+ +K E + +E K Q++ E++++ EQL
Sbjct: 844 LFTKVKPLLQVTRQDEVMQAKVVELQKVKDTQVKTETELKEMANKYQQLLEEKSILAEQL 903
Query: 2686 QQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXX 2865
Q E+E AE +++R RL ++ QELE I++D+ R+ ++K + ++D
Sbjct: 904 QAETELFAEAEEMRSRLSSKKQELEDILHDLESRVEEEEERTLQLQNEKKKMHQHIQDLE 963
Query: 2866 XXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLL 3045
+K + +D T+ +
Sbjct: 964 EQLEEEEGARQKLQLEKVTTESKLKKMEENILLLEDQNAKLAKERKLLDERISDFTSTMA 1023
Query: 3046 DHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMG 3225
+ EE+ K K + + E + +LE L +E + + E+E+ KRKL E D +D L E
Sbjct: 1024 EEEEKVKSLNKLRNKYEAVIADLEDRLKKEEKGRQEMEKMKRKLDGETTDLQDQLLELQQ 1083
Query: 3226 KVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNK 3405
++EEL QL +++EELQ L R D+E + KQ+RD+Q+ + E ED+E+E+ AR K
Sbjct: 1084 QIEELKQQLARKEEELQAALARIDDEVGQKNNLLKQLRDLQSQLAEFHEDLESEKVARAK 1143
Query: 3406 AEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEE 3585
AE RR++ +LE +K ++ D +D Q+L +++++EV K+ IE+ + ++ E
Sbjct: 1144 AEKQRRDLGEELEALKTELEDTLDSTATQQELRTKREQEVTDLKKTIEEESKVRDAQVAE 1203
Query: 3586 QKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKI 3765
+ + ++ VEE+ +Q+EQ ++ + LEK + + E D+ +E+ LQA++ D +++RK
Sbjct: 1204 MRQRHNQVVEEISEQLEQARRFKGNLEKVKQTLESENIDLIKEVKNLQATKQDSEQRRKK 1263
Query: 3766 HEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
E + E Q +S++ K L ++L + + ELD ++ E + + L+T
Sbjct: 1264 LEQQVSEFQIRANDSEKIKAELAEKLHKLQAELDGVSGALGSTESKSIKLNKDLSTVQSQ 1323
Query: 3946 XXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEA 4125
TR K+ +R RQLE+EKN +L+ EE E +A L ++I A +Q E+
Sbjct: 1324 LQDTQELLQEKTRQKLNFSSRVRQLEEEKNNILENLEEEEAAKAQLTRQIQALQQQLIES 1383
Query: 4126 RRK 4134
++K
Sbjct: 1384 KKK 1386
Score = 136 bits (342), Expect = 7e-30
Identities = 113/541 (20%), Positives = 241/541 (43%), Gaps = 17/541 (3%)
Frame = +1
Query: 3088 RLENQLHELE---QDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMK 3258
+ E +L E+ Q L E+ +E Q + +L AE E+ + L+ K ++E++ + L
Sbjct: 877 KTETELKEMANKYQQLLEEKSILAEQLQAETELFAEAEEMRSRLSSKKQELEDILHDLES 936
Query: 3259 RDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQ 3438
R EE E +Q + + M I +L E +E E AR K ++ + ++
Sbjct: 937 RVEE----------EEERTLQLQNEKKKMHQHIQDLEEQLEEEEGARQKLQLEKVTTESK 986
Query: 3439 LEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEE 3618
L+K++ ++L D+ L DE ++ + + + ++ + + + K+ + +
Sbjct: 987 LKKMEENILLLEDQNAKLAKERKLLDERISDFTSTMAEEEEKVKS-LNKLRNKYEAVIAD 1045
Query: 3619 LHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQAN 3798
L D++++ +K R ++EK + + D E D+ ++ LQ ++ ++ E L A
Sbjct: 1046 LEDRLKKEEKGRQEMEKMKRKLDGETTDLQDQLLELQQQIEELKQQLARKEEELQAALAR 1105
Query: 3799 LAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXX 3978
+ + K L+ QL + +L + E E+ A A +++
Sbjct: 1106 IDDEVGQKNNLLKQLRDLQSQLAEFHEDLESEKVARAKAEKQRRDLG------------- 1152
Query: 3979 TRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQ 4158
L+ E LD + LR E+E+ ++ E + + Q
Sbjct: 1153 --------EELEALKTELEDTLDSTATQQELRTKREQEVTDLKKTIEEESKVRDA----Q 1200
Query: 4159 LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKR 4338
+ E+R+++ + VE + +QLE++ K + + K+ ++ E D E++N++A+ +DSE+R
Sbjct: 1201 VAEMRQRHNQVVEEISEQLEQARRFKGNLEKVKQTLESENIDLIKEVKNLQATKQDSEQR 1260
Query: 4339 QKKFESQMAEERV--------------AVQKALLDRDAMSQELRDRETRVLSLLNEVDIM 4476
+KK E Q++E ++ + K + D +S L E++ + L ++ +
Sbjct: 1261 RKKLEQQVSEFQIRANDSEKIKAELAEKLHKLQAELDGVSGALGSTESKSIKLNKDLSTV 1320
Query: 4477 KEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNL 4656
+ L+++ Q+ LQ+ K +F V +LE+ K ++ L + +L +
Sbjct: 1321 QSQLQDT-------QELLQEKTRQKLNFSSRVRQLEEEKNNILENLEEEEAAKAQLTRQI 1373
Query: 4657 Q 4659
Q
Sbjct: 1374 Q 1374
Score = 90.1 bits (222), Expect = 6e-16
Identities = 114/541 (21%), Positives = 232/541 (42%), Gaps = 44/541 (8%)
Frame = +1
Query: 4003 NRARQLEDEKNALLDEKE-------EAEGLRAHLEKEIHAARQGAG--EARRKAEESVNQ 4155
N+ +QL +EK+ L ++ + EAE +R+ L + E+R + EE
Sbjct: 887 NKYQQLLEEKSILAEQLQAETELFAEAEEMRSRLSSKKQELEDILHDLESRVEEEEERTL 946
Query: 4156 QLEELRKKNLRDVEHLQKQLEESEVAKERI------LQSKKKIQQE----LEDSSMELEN 4305
QL+ +KK + ++ L++QLEE E A++++ +SK K +E LED + +L
Sbjct: 947 QLQNEKKKMHQHIQDLEEQLEEEEGARQKLQLEKVTTESKLKKMEENILLLEDQNAKLAK 1006
Query: 4306 VR-----------ASHRDSEKRQK-------KFESQMAEERVAVQKALLDRDAMSQELRD 4431
R ++ + E++ K K+E+ +A+ ++K R M + R
Sbjct: 1007 ERKLLDERISDFTSTMAEEEEKVKSLNKLRNKYEAVIADLEDRLKKEEKGRQEMEKMKRK 1066
Query: 4432 RETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAE 4611
+ L +++ +++ +EE + ++ELQ +++ DD + L K R L+++
Sbjct: 1067 LDGETTDLQDQLLELQQQIEELKQQLARKEEELQAALARIDDEVGQKNNLLKQLRDLQSQ 1126
Query: 4612 LNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRD 4791
L + +E + AE R L +ALK+E + + + + +E R +++ D
Sbjct: 1127 LAEFHEDLESEKVARAKAEKQRRDLGEELEALKTELEDTLDSTATQ-QELRTKREQEVTD 1185
Query: 4792 LENELENEKRGKSGAVSHRKKIENQ-IGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQI 4968
L+ +E E + + V+ ++ NQ + E+ +QLE A R K
Sbjct: 1186 LKKTIEEESKVRDAQVAEMRQRHNQVVEEISEQLEQARRFKG------------------ 1227
Query: 4969 ECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAK 5148
E+ +Q E L + + +A + + EQ R+ E + +
Sbjct: 1228 NLEKVKQTLESENIDLIKEVKNLQATKQDSEQRRKKLEQQVSEFQ--------------- 1272
Query: 5149 GGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQK 5328
I + + +++A++A+ A+ ++L + DLS ++ Q
Sbjct: 1273 ---IRANDSEKIKAELAEKLHKLQAELDGVSGALGSTESKSIKLNK---DLSTVQSQLQD 1326
Query: 5329 TEAEKQSLERSNRDYKAKITELESGAQS------RARAQMAALEAKVQYLEDQLNVEGQE 5490
T+ Q R ++ +++ +LE + A A L ++Q L+ QL +E ++
Sbjct: 1327 TQELLQEKTRQKLNFSSRVRQLEEEKNNILENLEEEEAAKAQLTRQIQALQQQL-IESKK 1385
Query: 5491 K 5493
K
Sbjct: 1386 K 1386
Score = 52.4 bits (124), Expect = 1e-04
Identities = 56/272 (20%), Positives = 114/272 (41%), Gaps = 12/272 (4%)
Frame = +1
Query: 4963 QIECE-EARQAKEDIAALLREADRKFRAVEAEREQLREANE--GLMQARKQXXXXXXXXX 5133
Q++ E E ++ LL E ++AE E EA E + ++KQ
Sbjct: 875 QVKTETELKEMANKYQQLLEEKSILAEQLQAETELFAEAEEMRSRLSSKKQELEDILHDL 934
Query: 5134 XXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMER 5313
R + EE+R L+ + + +L ++ + ++QLE++TT+ +++
Sbjct: 935 ESR-----VEEEEERTLQLQNEKKKMHQHIQDLEEQLEEEEGARQKLQLEKVTTESKLKK 989
Query: 5314 T---------LNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLED 5466
N K E++ L+ D+ + + E E +S + + EA + LED
Sbjct: 990 MEENILLLEDQNAKLAKERKLLDERISDFTSTMAEEEEKVKSLNKLRNK-YEAVIADLED 1048
Query: 5467 QLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDE 5646
+L E + + + R+L+ D Q + ++ E+ K+ L + K L+ L
Sbjct: 1049 RLKKEEKGRQEMEKMKRKLDGETTDLQDQLLELQQQIEELKQQLAR---KEEELQAALAR 1105
Query: 5647 AEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
+DE+ ++ + ++ L + +E L E
Sbjct: 1106 IDDEVGQKNNLLKQLRDLQSQLAEFHEDLESE 1137
>gi|553596|gb|AAA59888.1| cellular myosin heavy chain
Length = 1337
Score = 1371 bits (3548), Expect = 0.0
Identities = 698/1347 (51%), Positives = 928/1347 (68%), Gaps = 8/1347 (0%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL V + + +P A WA +KL WVP GF S+K E +E +VELV+ ++V +
Sbjct: 8 KYLYVDKNFINNPLAQADWAAKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKV 67
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDM+ELT LNEASVLHNLK+RYYS LIYTYSGLFCVVINPYK L
Sbjct: 68 NKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNL 127
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYSE+++E +KGKKRHEMPPHI+AI DTAYRSM+Q+REDQSILCTGESGAGKTENTKKV
Sbjct: 128 PIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKV 187
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
IQYLA+VA + ++K GELE QLLQANPILEAFGN+KTVKND
Sbjct: 188 IQYLAYVASSHKSKKDQ-----------------GELERQLLQANPILEAFGNAKTVKND 230
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA++ER+FHIFY +L G K+
Sbjct: 231 NSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKT 290
Query: 913 EYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 1092
+ LLE + YRFL N +T+P D F T+ +MRIMG ++E ++RV+S VL LG
Sbjct: 291 DLLLEPYNKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLG 350
Query: 1093 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA 1272
N+ F +E+ +DQA + D+ QKV HLLG+ V + + L PRIKVGR++V KAQ +EQA
Sbjct: 351 NIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQA 410
Query: 1273 EFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICIN 1452
+FA+EA+AKA+YER+F+WLV RINK+LD+T RQGASFIGILDIAGFEIFD+NSFEQ+CIN
Sbjct: 411 DFAIEALAKATYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCIN 470
Query: 1453 YTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDE 1623
YTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP IDLIEKP G+LALLDE
Sbjct: 471 YTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDE 530
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMD 1800
EC FPKA DKSFVEK+ + HPKF P ++ K+ F ++HYAG+VDY AD+WLMKNMD
Sbjct: 531 ECWFPKATDKSFVEKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMD 590
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQLH 1968
PLN+N+ L+ S+D FV+ +WKD + G+ A M+ETA ++RKGMFRTV QL+
Sbjct: 591 PLNDNIATLLHQSSDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLY 650
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
KEQL KLM TLRNT+P+FVRCIIPNHEKK+GK++ +LVL+QLRCNGVLEGIRICRQGFPN
Sbjct: 651 KEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPN 710
Query: 2149 RVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAH 2328
RV FQEFR RYEILTP+ IPK F+DGK++ MI AL++D+NLYRIGQSKVFFR GVLAH
Sbjct: 711 RVVFQEFRQRYEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAH 770
Query: 2329 LEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRL 2508
LEEERDLK+T +I+ FQA CRG+L+R+ + N AYLKLRNWQWWRL
Sbjct: 771 LEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRL 830
Query: 2509 FTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQ 2688
FTKVKPLLQV+R ++E+ AK++EL +E+ L E+ E E Q++ E+ +QEQLQ
Sbjct: 831 FTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQ 890
Query: 2689 QESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXX 2868
E+E AE +++R RL + QELE I +D+ R+ ++K + +++
Sbjct: 891 AETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEE 950
Query: 2869 XXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLD 3048
+K + +D TT L +
Sbjct: 951 QLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTE 1010
Query: 3049 HEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGK 3228
EE++K K K + E + +LE+ L RE + + ELE+ +RKL + D D +AE +
Sbjct: 1011 EEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQ 1070
Query: 3229 VEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKA 3408
+ EL QL K++EELQ L R +EE+A + K++R++++ I EL+ED+E+ER +RNKA
Sbjct: 1071 IAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKA 1130
Query: 3409 EMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQ 3588
E +R++ +LE +K ++ D +D Q+L S++++EVN K+ +E+ T E +I+E
Sbjct: 1131 EKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEM 1190
Query: 3589 KAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIH 3768
+ K S+ VEEL +Q+EQ K+ ++ LEK + + ER ++A E+ +L + D + KRK
Sbjct: 1191 RQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKV 1250
Query: 3769 EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXX 3948
EA L E+Q E + + L D++ + + ELD++ + + + + + + +
Sbjct: 1251 EAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQL 1310
Query: 3949 XXXXXXXXXXTRLKIANINRARQLEDE 4029
R K++ + +Q+EDE
Sbjct: 1311 QDTQELLQEENRQKLSLSTKLKQVEDE 1337
Score = 102 bits (253), Expect = 1e-19
Identities = 110/558 (19%), Positives = 240/558 (42%), Gaps = 23/558 (4%)
Frame = +1
Query: 3502 MSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSR--QVEELHDQIEQHKKQRSQLEKQQ 3675
+SR++EE+ A + + +++ E+Q A +R ++E L Q+ K Q ++Q
Sbjct: 840 VSRQEEEMMAKEEELVKVR-------EKQLAAENRLTEMETLQSQLMAEKLQL----QEQ 888
Query: 3676 NQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSR 3855
QA+ E A+E+ RA + K++ E +++A + E +E + L + ++ +
Sbjct: 889 LQAETELCAEAEEL------RARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQ 942
Query: 3856 DELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKN 4035
+ L EEEE A +Q K+ + ++LE+E+
Sbjct: 943 QNIQELEEQLEEEESARQKLQLE---------------------KVTTEAKLKKLEEEQI 981
Query: 4036 ALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQL 4215
L D+ + EK++ R EE ++ L +L+ K+ + L+++L
Sbjct: 982 ILEDQN-----CKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERL 1036
Query: 4216 EESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKAL 4395
E ++ + ++++K++ + D S ++ ++A + + + K E ++ V++
Sbjct: 1037 RREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEA 1096
Query: 4396 LDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVH 4575
++ +++R+ E+++ L ++ ES+R R+
Sbjct: 1097 AQKNMALKKIRELESQISELQEDL--------ESERASRN-------------------- 1128
Query: 4576 ELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAE 4755
+ EK KR L EL ++ ++E+ D+ ++ R + E LK + + + +
Sbjct: 1129 KAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQ 1188
Query: 4756 EKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXX 4935
E R+ + + +L +LE KR K+ ++ +EN+ GEL +++V + K +
Sbjct: 1189 EMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRK 1248
Query: 4936 XXXXXXXEYQIECEEARQAKEDIA--------------ALLREADRK-------FRAVEA 5052
E Q++ E + + ++A LL ++D K F A+E+
Sbjct: 1249 KVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALES 1308
Query: 5053 EREQLREANEGLMQARKQ 5106
QL++ E L + +Q
Sbjct: 1309 ---QLQDTQELLQEENRQ 1323
Score = 101 bits (252), Expect = 2e-19
Identities = 109/502 (21%), Positives = 216/502 (42%), Gaps = 52/502 (10%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYK-------SELEQHKRKLLAE---LEDSKDHLAEKMGKVEE 3237
R E ++ E++L + R+ + +E+E + +L+AE L++ E + EE
Sbjct: 842 RQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEE 901
Query: 3238 LNNQLMKRDEELQ---HQL-TRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNK 3405
L +L + +EL+ H L R +EE +Q + + MQ I EL E +E E +AR K
Sbjct: 902 LRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQK 961
Query: 3406 AEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEE 3585
++ + A+L+K++ +E +L+D + +E + I + + + E+
Sbjct: 962 LQLEKVTTEAKLKKLE-------EEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEK 1014
Query: 3586 QKA------KFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADI 3747
K+ K + +L +++ + +KQR +LEK + + + + D++ +IA LQA A++
Sbjct: 1015 SKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAEL 1074
Query: 3748 D----------------------------KKRKIHEAHLMEIQANLAESDEHKRTLIDQL 3843
KK + E+ + E+Q +L ES+ R ++
Sbjct: 1075 KMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDL-ESERASRNKAEKQ 1133
Query: 3844 ERSR-DELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQL 4020
+R +EL+ L E+ + A Q + + A I RQ
Sbjct: 1134 KRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQK 1193
Query: 4021 EDEK-NALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQ--LEELRKKNLRD 4191
+ L ++ E+ + ++A+LEK GE + + + + E RKK
Sbjct: 1194 HSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQ 1253
Query: 4192 VEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEE 4371
++ LQ + E E + + K+Q EL++ + L + K ESQ+ +
Sbjct: 1254 LQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDT 1313
Query: 4372 RVAVQKALLDRDAMSQELRDRE 4437
+ +Q+ + ++S +L+ E
Sbjct: 1314 QELLQEENRQKLSLSTKLKQVE 1335
Score = 92.0 bits (227), Expect = 2e-16
Identities = 123/581 (21%), Positives = 234/581 (40%), Gaps = 50/581 (8%)
Frame = +1
Query: 4066 GLRAHLEKE---------IHAARQGAGEARRKAEESVNQQLEELR--KKNLRDVEHLQKQ 4212
G+ AHLE+E I G RKA QQL ++ ++N L+
Sbjct: 766 GVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNW 825
Query: 4213 LEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFE---SQMAEERVAV 4383
K + L + ++E+ EL VR +E R + E SQ+ E++ +
Sbjct: 826 QWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQL 885
Query: 4384 QKAL---LDRDAMSQELRDRETRVLSLLNEV-DIMKEHLEESDRVRRSLQQELQDSISNK 4551
Q+ L + A ++ELR R T L E+ ++ +EE + + LQ E + N
Sbjct: 886 QEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNI 945
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAI 4731
+ + + E E A++ L+ E ++++LE+ I ED +L + L+
Sbjct: 946 QELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFT 1005
Query: 4732 SNKDVEAEEKRRGLLK-------QIRDLENELENEKRGKSGAVSHRKKIE-------NQI 4869
+N E EEK + L K I DLE L E++ + R+K+E +QI
Sbjct: 1006 TNL-TEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQI 1064
Query: 4870 GELEQQL-EVANRL---KEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKF 5037
EL+ Q+ E+ +L +EE + + ++ R+ + I+ L + + +
Sbjct: 1065 AELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESER 1124
Query: 5038 RAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXX 5217
+ +Q R+ E L + + + KR E I +
Sbjct: 1125 ASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ------ELRSKREQEVNILKKTLEE 1178
Query: 5218 XXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELE 5397
++ +Q+ +Q +E++ L + + E KQ+LE + ++ L
Sbjct: 1179 EAKTHEAQIQEMRQKHSQA-VEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLL 1237
Query: 5398 SGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTT---------- 5547
G + + + +EA++Q L+ + N + +T +L+ L++ T
Sbjct: 1238 QG-KGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKS 1296
Query: 5548 ----QQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDE 5658
+ F + + +ELL++ N + +L +L + EDE
Sbjct: 1297 SKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDE 1337
Score = 52.8 bits (125), Expect = 1e-04
Identities = 60/306 (19%), Positives = 124/306 (39%), Gaps = 9/306 (2%)
Frame = +1
Query: 4852 KIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADR 5031
K E + E+QL NRL E +++ +E QA+ ++ A E
Sbjct: 850 KEEELVKVREKQLAAENRLTEMETLQSQLMAE-----KLQLQEQLQAETELCAEAEELRA 904
Query: 5032 KFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXX 5211
+ A + E E++ E ++ ++ EK++++ I +
Sbjct: 905 RLTAKKQELEEICHDLEARVEEEEERCQHLQA--------------EKKKMQQNIQELEE 950
Query: 5212 XXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERT---------LNQKTEAEKQSLERSN 5364
+L ++ + ++QLE++TT+ +++ N K EK+ LE
Sbjct: 951 ---------QLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRI 1001
Query: 5365 RDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDT 5544
++ +TE E ++S A+ + EA + LE++L E +++ + R+LE D
Sbjct: 1002 AEFTTNLTEEEEKSKSLAKLKNKH-EAMITDLEERLRREEKQRQELEKTRRKLEGDSTDL 1060
Query: 5545 TQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDAN 5724
+ Q + + + K L K K L+ L E+E +++ + ++ + +
Sbjct: 1061 SDQIAELQAQIAELKMQLAK---KEEELQAALARVEEEAAQKNMALKKIRELESQISELQ 1117
Query: 5725 EQLTRE 5742
E L E
Sbjct: 1118 EDLESE 1123
>gi|47211645|emb|CAF92169.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 2310
Score = 1354 bits (3505), Expect = 0.0
Identities = 790/1896 (41%), Positives = 1121/1896 (58%), Gaps = 89/1896 (4%)
Frame = +1
Query: 325 TYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSIL 504
TYSGLFCVVINPYK LPIYSE++IE ++GKKRHEMPPHI+AI+++AYR MLQ+REDQSIL
Sbjct: 307 TYSGLFCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSIL 366
Query: 505 CTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQA 684
CTGESGAGKTENTKKVIQYLAHVA + + + N GELE QLLQA
Sbjct: 367 CTGESGAGKTENTKKVIQYLAHVASSHKGRK--------------DHNIPGELERQLLQA 412
Query: 685 NPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE-----------FYLLEKSR 831
NPILE+FGN+KTVKNDNSSRFGKFIRINFD++GYI GANIE LLEKSR
Sbjct: 413 NPILESFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETCILIPWLKVFLNLLEKSR 472
Query: 832 VLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTI 1011
+RQA+DER+FHIFY++L G +++ LLEG +NYRFL N I +P D F T+
Sbjct: 473 AIRQAKDERTFHIFYRLLAGAGEHLRTDLLLEGFNNYRFLSNGNIPIPGQQDKDNFQETL 532
Query: 1012 NSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVI 1191
++MRIM F+ +EI V ++L+ + T +L V +LL L +
Sbjct: 533 DAMRIMSFSHEEI-----VCYHLILVAHYSST----FIHPVLLGKISQNSVSYLLPLYLS 583
Query: 1192 ELQKAFLRP----RIKVGREFVNKAQNQEQAEFAVEA-----------------IAKASY 1308
P + + +QNQ E+ +A +
Sbjct: 584 LFSGTEALPPSWDECNGVHQSNSDSQNQSWTRLCTESSDQRTDSLRYLEKINENMADFAV 643
Query: 1309 ERLFKWLVTRI--------NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNE 1464
E L K R+ NK+LDRT RQGASFIGILDIAGFEIF +NSFEQ+CINYTNE
Sbjct: 644 EALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFQLNSFEQLCINYTNE 703
Query: 1465 KLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEK---PMGVLALLDEECLF 1635
KLQQLFN+TMFILEQEEYQREGIEW FIDFGLDLQP IDLIE+ P G+LALLDEEC F
Sbjct: 704 KLQQLFNHTMFILEQEEYQREGIEWSFIDFGLDLQPCIDLIERPNNPPGILALLDEECWF 763
Query: 1636 PKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNE 1812
PKA DK+F++K+ + H KF P ++ K+ F+++HYAGRVDY AD+WLMKNMDPLN+
Sbjct: 764 PKATDKTFIDKVLQEQGTHSKFQKPRQLKDKADFSIIHYAGRVDYKADEWLMKNMDPLND 823
Query: 1813 NVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAFG--MRSRKGMFRTVSQLHKEQL 1980
NV L+ STD FVA +WKD + G+ A MNETAFG +++KGMFRTV QL+KEQL
Sbjct: 824 NVATLLHQSTDKFVAELWKDVDRIVGLDQVAGMNETAFGAAYKTKKGMFRTVGQLYKEQL 883
Query: 1981 TKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPF 2160
+KLM TLRNT+P+FVRCIIPNHEK++GK++S+LVL+QLRCNGVLEGIRICRQGFPNR+ F
Sbjct: 884 SKLMATLRNTNPNFVRCIIPNHEKRAGKLDSHLVLDQLRCNGVLEGIRICRQGFPNRIVF 943
Query: 2161 QEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEE 2340
QEFR RYEILTP+ IPK F+DGK++ +MI AL++D NL+RIGQSK+FFR GVLAHLEEE
Sbjct: 944 QEFRQRYEILTPNAIPKGFMDGKQACERMIQALELDGNLFRIGQSKIFFRAGVLAHLEEE 1003
Query: 2341 RDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKV 2520
RDLK+T +I+ FQA CRG+L+R+ + N AYLKLR+WQWWRLFTKV
Sbjct: 1004 RDLKITDIIIYFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRLFTKV 1063
Query: 2521 KPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQV---------------- 2652
KPLLQVTR ++E++AKD+EL KE+ K+E E E K QV
Sbjct: 1064 KPLLQVTRQEEEMQAKDEELVKVKEKQTKVEGQLVEMETKNQQVRISDFQPQIKPVFWES 1123
Query: 2653 ---------IVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXX 2805
+ E+ ++ EQLQ E+E AE +++R RL +R QELE I++D+ RL
Sbjct: 1124 WLKIIYVQLLEEKNILAEQLQAETELFAEAEEMRARLASRKQELEEILHDLESRLEEEEE 1183
Query: 2806 XXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDX 2985
++K ++D +K + +D
Sbjct: 1184 RNQTIQNEKKKMQSHIQDLEEQLDEEEATRQKLQLEKVTTEAKMKKLEEDVLLLEDQNSK 1243
Query: 2986 XXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQH 3165
+++ L + EE+AK+ K K + E + +LE+ L +E + + ELE+
Sbjct: 1244 FVKEKKLLEDRINEMSSLLAEEEEKAKNLGKLKNKQEMMMVDLEERLKKEEKTRQELEKA 1303
Query: 3166 KRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDM 3345
KRKL E D +D +AE ++EEL Q+ K++EE Q R ++E+ KQ+R++
Sbjct: 1304 KRKLDGETSDFQDQIAEFQTQMEELKGQIGKKEEEQQLMQARNEDEATQKNNALKQLREL 1363
Query: 3346 QTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEV 3525
Q + EL+ED+E+E+ ARNKAE +R++ +LE +K ++ D +D Q+L +++++EV
Sbjct: 1364 QAQLSELQEDLESEKLARNKAEKLKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEV 1423
Query: 3526 NATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADM 3705
K+ I++ E +I+E + + + +EEL +Q+EQ K+ + LEK + + ++
Sbjct: 1424 AELKKTIDEETKNHESQIQEMRQRHATALEELSEQLEQAKRFKGNLEKTKQSLESNNKEL 1483
Query: 3706 AQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVR 3885
A E+ LQ + + + KRK EA L E+ A + E + K L D+ + + ELD++ +
Sbjct: 1484 ASEVKSLQQGKTESEHKRKKLEAQLQELTARVTEGERVKGELSDRSHKLQTELDNVCALL 1543
Query: 3886 EEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAE 4065
E+ E M + ++ TR K+ +R RQLE+EKN L +++EE E
Sbjct: 1544 EDAERKCIKMAKDVSGLESQLQDQQELLQEETRQKLNLSSRLRQLEEEKNTLQEQQEEDE 1603
Query: 4066 GLRAHLEKEIHAARQGAGEARRKAEESVN--QQLEELRKKNLRDVEHLQKQLEESEVAKE 4239
R +LEK+I + E+++K E+ + LEE++KK +++E ++LEE + E
Sbjct: 1604 EARKNLEKQIQTLQTQLSESKKKLEDDLGTIDSLEEVKKKLQKELELTTQRLEEKTIGFE 1663
Query: 4240 RILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQ 4419
++ ++K ++QQEL+D +++L++ R + EK+QKKF+ +AEE+ + +RD
Sbjct: 1664 KMEKTKTRLQQELDDLTVDLDHQRQIVSNLEKKQKKFDQMLAEEKNISARYAEERDRAEA 1723
Query: 4420 ELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNV--------- 4572
E R++ET+ LSL ++ E EE +RV + L+ E++D +S+KDD GKN
Sbjct: 1724 EAREKETKALSLARALEEALEAKEELERVNKQLRTEMEDLMSSKDDVGKNAMKAQYERDL 1783
Query: 4573 ----HELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNK 4740
+ ++ KR+L ++ +M ++E+ +A A+ +LE+ + ++S + A +
Sbjct: 1784 QGRDDQNDEKKRALVKQVREMEAELEDERKQKALAVAAKKKLEMDLKDIESHIEGANKAR 1843
Query: 4741 DVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEY 4920
D EA ++ R L Q++D + ELE+ + + + K+ E ++ LE ++
Sbjct: 1844 D-EAIKQLRKLQAQMKDYQRELEDTRASRDDIFAICKETEKKLKSLEAEIV--------- 1893
Query: 4921 XXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQAR 5100
Q ED+AA ++R R E ER++L++
Sbjct: 1894 ----------------------QLHEDLAA----SERGRRHAEQERDELQD--------- 1918
Query: 5101 KQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQL 5280
G +EKRRLEA+IAQ Q N EL D+ RK +Q
Sbjct: 1919 ---------EISNSTSGKSALMDEKRRLEARIAQLEEELEEEQGNMELLNDRFRKTTMQE 1969
Query: 5281 EQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYL 5460
+ + TDLS ER+ QK+E +Q LER N++ KAK++ELE +SR +A + ALEAK+ L
Sbjct: 1970 DTLMTDLSAERSSAQKSENARQQLERQNKELKAKLSELEGSVKSRFKASITALEAKIAQL 2029
Query: 5461 EDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKEL-LEKSNLKNRNLRRQ 5637
E+QL E +E+ AAN+ ARR EK++ + Q EDE+R +Q KE L S R+ ++
Sbjct: 2030 EEQLEQEAKERAAANKIARRTEKKMKEICMQVEDERRHADQFKEQDLAASERGRRHAEQE 2089
Query: 5638 LDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
DE +DE+S + + E L QL EL
Sbjct: 2090 RDELQDEISNSTSGKSALMDEKRRLEARIAQLEEEL 2125
Score = 325 bits (834), Expect = 6e-87
Identities = 288/1142 (25%), Positives = 511/1142 (44%), Gaps = 84/1142 (7%)
Frame = +1
Query: 2572 DELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQ 2751
+E + + + +E E E ++ +E+ + ++++ E+ L+D + +
Sbjct: 1190 NEKKKMQSHIQDLEEQLDEEEATRQKLQLEKVTTEAKMKKLEEDVLLLEDQNSKFVKEKK 1249
Query: 2752 ELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQ 2931
LE +N+M L+ + KQ + D K +D
Sbjct: 1250 LLEDRINEMSSLLAEEEEKAKNLGKLKNKQEMMMVDLEERLKKEEKTRQELEKAKRKLDG 1309
Query: 2932 XXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHE 3111
Q + + + D + + +K L+ QL E
Sbjct: 1310 ETSDFQDQIAEFQTQMEELKGQIGKKEEEQQLMQARNEDEATQKNNALKQLRELQAQLSE 1369
Query: 3112 LEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTR 3291
L++DL E+ +++ E+ KR L ELE K L + + KR++E+
Sbjct: 1370 LQEDLESEKLARNKAEKLKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKT 1429
Query: 3292 YDEESANVTLMQKQMRDMQTT-IDELREDMETERNARNKAEMT----------------- 3417
DEE+ N ++MR T ++EL E +E + + E T
Sbjct: 1430 IDEETKNHESQIQEMRQRHATALEELSEQLEQAKRFKGNLEKTKQSLESNNKELASEVKS 1489
Query: 3418 -----------RREVVAQL----------EKVKGDVLDK-------VDEATMLQDLMSRK 3513
R+++ AQL E+VKG++ D+ +D L + RK
Sbjct: 1490 LQQGKTESEHKRKKLEAQLQELTARVTEGERVKGELSDRSHKLQTELDNVCALLEDAERK 1549
Query: 3514 DEEVNATKRAIE-QIQHTMEGKIEEQKAKFS-----RQVEE----LHDQIEQHKKQRSQL 3663
++ +E Q+Q E EE + K + RQ+EE L +Q E+ ++ R L
Sbjct: 1550 CIKMAKDVSGLESQLQDQQELLQEETRQKLNLSSRLRQLEEEKNTLQEQQEEDEEARKNL 1609
Query: 3664 EKQ----QNQADQERADMAQEIAL---LQASRADIDKKRKIHEAHLMEIQANLAESDEHK 3822
EKQ Q Q + + + ++ L+ + + K+ ++ L E + ++ K
Sbjct: 1610 EKQIQTLQTQLSESKKKLEDDLGTIDSLEEVKKKLQKELELTTQRLEEKTIGFEKMEKTK 1669
Query: 3823 RTLIDQLERSRDELDHLNRV---REEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKI 3993
L +L+ +LDH ++ E+++ F M R K
Sbjct: 1670 TRLQQELDDLTVDLDHQRQIVSNLEKKQKKFDQMLAEEKNISARYAEERDRAEAEAREKE 1729
Query: 3994 AN-INRARQLEDEKNALLDEKEEAEGLRAHLEKEIH---AARQGAGEARRKAE-----ES 4146
++ AR LE+ L+ KEE E + L E+ +++ G+ KA+ +
Sbjct: 1730 TKALSLARALEEA----LEAKEELERVNKQLRTEMEDLMSSKDDVGKNAMKAQYERDLQG 1785
Query: 4147 VNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRD 4326
+ Q +E ++ ++ V ++ +LE+ K + +KKK++ +L+D +E + +
Sbjct: 1786 RDDQNDEKKRALVKQVREMEAELEDERKQKALAVAAKKKLEMDLKDIESHIEGANKARDE 1845
Query: 4327 SEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRV 4506
+ K+ +K ++QM + + ++ RD + ++ E ++ SL E+ + E L S+R
Sbjct: 1846 AIKQLRKLQAQMKDYQRELEDTRASRDDIFAICKETEKKLKSLEAEIVQLHEDLAASERG 1905
Query: 4507 RRSLQQE---LQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDAR 4677
RR +QE LQD ISN GK+ L KR LEA + + ++EE + N+++ D
Sbjct: 1906 RRHAEQERDELQDEISNSTS-GKSA--LMDEKRRLEARIAQLEEELEEEQGNMELLNDRF 1962
Query: 4678 LRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENEL-ENEKRGKSGAVSHRKK 4854
+ + L ++ S+ ++E R+ L +Q ++L+ +L E E KS +
Sbjct: 1963 RKTTMQEDTLMTDLSAERSSAQ-KSENARQQLERQNKELKAKLSELEGSVKSRFKASITA 2021
Query: 4855 IENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQ-----AKEDIAALLR 5019
+E +I +LE+QLE + + E ++ E+ R+ ++D+AA
Sbjct: 2022 LEAKIAQLEEQLEQEAKERAAANKIARRTEKKMKEICMQVEDERRHADQFKEQDLAA--- 2078
Query: 5020 EADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIA 5199
++R R E ER++L++ G +EKRRLEA+IA
Sbjct: 2079 -SERGRRHAEQERDELQDE------------------ISNSTSGKSALMDEKRRLEARIA 2119
Query: 5200 QXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKA 5379
Q Q N EL D+ RK +Q + + TDLS ER+ QK+E +Q LER N++ KA
Sbjct: 2120 QLEEELEEEQGNMELLNDRFRKTTMQADTLMTDLSAERSSAQKSENARQQLERQNKELKA 2179
Query: 5380 KITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFE 5559
K++ELE +SR +A + ALEAK+ LE+QL E +E+ AAN+ ARR EK++ + Q E
Sbjct: 2180 KLSELEGSVKSRFKASITALEAKIAQLEEQLEQEAKERAAANKIARRTEKKMKEICMQVE 2239
Query: 5560 DEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTR 5739
DE+R +Q KE +EK+N + + L+RQL+EAE+E +R R +QRE DD +A+E L+R
Sbjct: 2240 DERRHADQFKEQVEKANSRMKQLKRQLEEAEEEATRANASRRKLQRELDDATEASEGLSR 2299
Query: 5740 EL 5745
E+
Sbjct: 2300 EV 2301
>gi|28703810|gb|AAH47253.1| LOC398083 protein [Xenopus laevis]
Length = 1250
Score = 1342 bits (3472), Expect = 0.0
Identities = 685/1258 (54%), Positives = 886/1258 (69%), Gaps = 8/1258 (0%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL V R V +P A WA +KL WVP + GF SIK E DE +VEL + ++ +
Sbjct: 8 KYLYVDRNFVNNPLAQADWAAKKLVWVPSEKNGFEAASIKEEVGDEAIVELAENGKKAKV 67
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDMSEL LNEASVLHNLK+RYYS LIYTYSGLFCVVINPYK L
Sbjct: 68 NKDDIQKMNPPKFSKVEDMSELACLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNL 127
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYSE+++E +KGKKRHEMPPHI+AI DTAYRSM+Q+REDQSILCTGESGAGKTENTKKV
Sbjct: 128 PIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKV 187
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
IQYLA+VA + ++K GELE QLLQANPILEAFGN+KTVKND
Sbjct: 188 IQYLAYVATSHKSKKDQ-----------------GELERQLLQANPILEAFGNAKTVKND 230
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFY ++ G KS
Sbjct: 231 NSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKDERTFHIFYYLMSGAGEHLKS 290
Query: 913 EYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 1092
+ LLE + YRFL N +T+P D F T+ +M+IMGF D+E + ++RVVSAVL LG
Sbjct: 291 DLLLEAYNKYRFLSNGHVTIPGQLDKDLFQETMEAMKIMGFTDEEQTGLLRVVSAVLQLG 350
Query: 1093 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA 1272
N+ F +E+ +DQA + D+ QKVCHLLG+ V + + L PRIKVGR+FV KAQ +EQA
Sbjct: 351 NIAFKKERNTDQASMPDNTAAQKVCHLLGINVNDFTRGILLPRIKVGRDFVQKAQTKEQA 410
Query: 1273 EFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICIN 1452
+FA+EA+AKASYER+F+WLV R+NK+LD+T RQGASFIGILDIAGFEIF++NSFEQ+CIN
Sbjct: 411 DFAIEALAKASYERMFRWLVMRVNKALDKTKRQGASFIGILDIAGFEIFELNSFEQLCIN 470
Query: 1453 YTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDE 1623
YTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP IDLIE+P G+LALLDE
Sbjct: 471 YTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPAGPPGILALLDE 530
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMD 1800
EC FPKA DKSFVEK+ + H KF P ++ K+ F+++HYAGRVDY AD+WL+KNMD
Sbjct: 531 ECWFPKATDKSFVEKVVQEQGSHSKFQKPKQLKDKADFSIIHYAGRVDYKADEWLLKNMD 590
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQLH 1968
PLN+NV L+ S+D FV+ +WKD + G+ A M++TA ++RKGMFRTV QL+
Sbjct: 591 PLNDNVATLLNQSSDKFVSELWKDVDRIVGLDQVAGMSDTALPGAFKTRKGMFRTVGQLY 650
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
KEQL+KLM TLRNT+P+FVRCIIPNHEKKSGK++++LVL+QLRCNGVLEGIRICRQGFPN
Sbjct: 651 KEQLSKLMATLRNTNPNFVRCIIPNHEKKSGKLDAHLVLDQLRCNGVLEGIRICRQGFPN 710
Query: 2149 RVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAH 2328
RV FQEFR RYEILTP+ IPK F+DGK++ MI AL++D+NLYRIGQSKVFFR+GVLAH
Sbjct: 711 RVVFQEFRQRYEILTPNAIPKGFMDGKQACVLMIRALELDSNLYRIGQSKVFFRSGVLAH 770
Query: 2329 LEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRL 2508
LEEERDLK+T +I++FQA CRG+L+R+ + N AYLKLRNWQWWRL
Sbjct: 771 LEEERDLKITDVIISFQACCRGYLARKAFARRQQQLTAMKVIQRNCAAYLKLRNWQWWRL 830
Query: 2509 FTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQ 2688
FTKVKPLLQ R D+E+ AK+ EL+ K+ + E E E + E+ +QEQLQ
Sbjct: 831 FTKVKPLLQANRFDEELHAKEVELQKIKDLQVSSEQKVSEMENVQMMLQQEKMQLQEQLQ 890
Query: 2689 QESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXX 2868
E E AE +++R RL + QELE I++D+ R+ ++K + + +
Sbjct: 891 AEIELCAEAEEMRARLANKKQELEEILHDLESRVEEEEERCQILQTEKKKMQQNIVELEE 950
Query: 2869 XXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLD 3048
+K + +D TT L +
Sbjct: 951 QLEEEEAARQKLQLEKVTAEAKMKKLEEDVLVLEDQNTKLGKEKKLYEERIAEFTTNLTE 1010
Query: 3049 HEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGK 3228
EE++K K K + E + +LE+ L RE + + ELE+ +RKL + D D +AE +
Sbjct: 1011 EEEKSKSLAKLKNKHETMISDLEERLRREEKQRQELEKTRRKLEGDSTDLHDQIAELQAQ 1070
Query: 3229 VEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKA 3408
+ EL QL K++EELQ L R +EE+A L K++R++++ I EL+ED+E+ER ARNKA
Sbjct: 1071 IAELKLQLAKKEEELQAALARAEEEAAQKNLALKKIRELESQIGELQEDLESERAARNKA 1130
Query: 3409 EMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQ 3588
E +R++ +LE +K ++ D +D Q+L +++++EV K+ +E T EG+I+E
Sbjct: 1131 EKQKRDLGEELEALKTELEDTLDSTATQQELRTKREQEVTHLKKTLEDEARTHEGQIQEI 1190
Query: 3589 KAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRK 3762
+ K S+ VEEL +Q+EQ K+ + LEK + + ER ++A E+ L + D + K+K
Sbjct: 1191 RQKHSQAVEELSEQLEQTKRLKGNLEKAKQALEGERNELANEVKTLLQGKGDSEHKKK 1248
Score = 115 bits (289), Expect = 1e-23
Identities = 103/427 (24%), Positives = 198/427 (46%), Gaps = 10/427 (2%)
Frame = +1
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
+++ ++ L +E+ E Q + +L AE E+ + LA K ++EE+ + L R EE
Sbjct: 869 SEMENVQMMLQQEKMQLQEQLQAEIELCAEAEEMRARLANKKQELEEILHDLESRVEE-- 926
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
E ++Q + + MQ I EL E +E E AR K ++ + A+++K++
Sbjct: 927 --------EEERCQILQTEKKKMQQNIVELEEQLEEEEAARQKLQLEKVTAEAKMKKLEE 978
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIE 3636
DVL D+ T L +E + + + + + + + K K + +L +++
Sbjct: 979 DVLVLEDQNTKLGKEKKLYEERIAEFTTNLTEEEEKSKS-LAKLKNKHETMISDLEERLR 1037
Query: 3637 QHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDE 3816
+ +KQR +LEK + + + + D+ +IA LQA A++ + E E+QA LA ++E
Sbjct: 1038 REEKQRQELEKTRRKLEGDSTDLHDQIAELQAQIAELKLQLAKKEE---ELQAALARAEE 1094
Query: 3817 HKRTLIDQLERSRDELDHLNRVRE--EEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLK 3990
L++ R+ + ++E E E A N +
Sbjct: 1095 EAAQKNLALKKIRELESQIGELQEDLESERAARNKAEK---------------------- 1132
Query: 3991 IANINRARQLEDEKNALLDEKEEA-------EGLRAHLEKEI-HAARQGAGEARRKAEES 4146
+ R L +E AL E E+ + LR E+E+ H + EAR +
Sbjct: 1133 -----QKRDLGEELEALKTELEDTLDSTATQQELRTKREQEVTHLKKTLEDEAR-----T 1182
Query: 4147 VNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRD 4326
Q++E+R+K+ + VE L +QLE+++ K + ++K+ ++ E + + E++ + D
Sbjct: 1183 HEGQIQEIRQKHSQAVEELSEQLEQTKRLKGNLEKAKQALEGERNELANEVKTLLQGKGD 1242
Query: 4327 SEKRQKK 4347
SE ++KK
Sbjct: 1243 SEHKKKK 1249
Score = 109 bits (272), Expect = 9e-22
Identities = 97/469 (20%), Positives = 205/469 (43%), Gaps = 14/469 (2%)
Frame = +1
Query: 3280 QLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGD 3459
Q R+DEE + ++++D+Q + ++ +ME N M ++E + E+++ +
Sbjct: 839 QANRFDEELHAKEVELQKIKDLQVSSEQKVSEME------NVQMMLQQEKMQLQEQLQAE 892
Query: 3460 VLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQ----------KAKFSRQ 3609
+ + M L ++K E +E+I H +E ++EE+ K K +
Sbjct: 893 IELCAEAEEMRARLANKKQE--------LEEILHDLESRVEEEEERCQILQTEKKKMQQN 944
Query: 3610 VEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEI 3789
+ EL +Q+E+ + R +L+ ++ A+ + + +++ +L+ + K++K++E + E
Sbjct: 945 IVELEEQLEEEEAARQKLQLEKVTAEAKMKKLEEDVLVLEDQNTKLGKEKKLYEERIAEF 1004
Query: 3790 QANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXX 3969
NL E +E ++L + + L EE +++
Sbjct: 1005 TTNLTEEEEKSKSLAKLKNKHETMISDLEERLRREEKQRQELEK---------------- 1048
Query: 3970 XXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESV 4149
TR R+LE + L D+ E + A L+ ++ + A +AEE
Sbjct: 1049 ---TR---------RKLEGDSTDLHDQIAELQAQIAELKLQLAKKEEELQAALARAEEEA 1096
Query: 4150 NQQLEELRKKNLRDVE----HLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRAS 4317
Q+ L K +R++E LQ+ LE A+ + + K+ + +ELE ELE+ S
Sbjct: 1097 AQK--NLALKKIRELESQIGELQEDLESERAARNKAEKQKRDLGEELEALKTELEDTLDS 1154
Query: 4318 HRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEES 4497
++ + K E ++ + ++ + QE+R + ++ V+ + E LE++
Sbjct: 1155 TATQQELRTKREQEVTHLKKTLEDEARTHEGQIQEIRQKHSQA------VEELSEQLEQT 1208
Query: 4498 DRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEEL 4644
R++ + LEKAK++LE E N++ +++ L
Sbjct: 1209 KRLKGN---------------------LEKAKQALEGERNELANEVKTL 1236
Score = 82.4 bits (202), Expect = 1e-13
Identities = 89/377 (23%), Positives = 167/377 (43%), Gaps = 15/377 (3%)
Frame = +1
Query: 4015 QLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAG--EARRKAEESVNQQLEELRKKNLR 4188
QL+++ A ++ EAE +RA L + + E+R + EE Q L+ +KK +
Sbjct: 884 QLQEQLQAEIELCAEAEEMRARLANKKQELEEILHDLESRVEEEEERCQILQTEKKKMQQ 943
Query: 4189 DVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAE 4368
++ L++QLEE E A++++ +K+ E + +E E+V + K K E ++ E
Sbjct: 944 NIVELEEQLEEEEAARQKL--QLEKVTAEAKMKKLE-EDVLVLEDQNTKLGK--EKKLYE 998
Query: 4369 ERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISN 4548
ER+A L + ++ + L N+ + M LEE R +QEL+ +
Sbjct: 999 ERIAEFTTNLTEE------EEKSKSLAKLKNKHETMISDLEERLRREEKQRQELEKTRRK 1052
Query: 4549 KDDFGKNVHE-------------LEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLE 4689
+ ++H+ L+ AK+ E + R + E + NL + + L +
Sbjct: 1053 LEGDSTDLHDQIAELQAQIAELKLQLAKKEEELQAALARAEEEAAQKNLALKKIRELESQ 1112
Query: 4690 VTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQI 4869
+ ES+RA NK AE+++R L +++ L+ ELE+ + R K E ++
Sbjct: 1113 IGELQEDLESERAARNK---AEKQKRDLGEELEALKTELEDTLDSTATQQELRTKREQEV 1169
Query: 4870 GELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVE 5049
L++ LE +E ++ EE + E L ++ +A+E
Sbjct: 1170 THLKKTLE------DEARTHEGQIQEIRQKHSQAVEELSEQLEQTKRLKGNLEKAKQALE 1223
Query: 5050 AEREQLREANEGLMQAR 5100
ER +L + L+Q +
Sbjct: 1224 GERNELANEVKTLLQGK 1240
Score = 70.1 bits (170), Expect = 6e-10
Identities = 82/392 (20%), Positives = 156/392 (38%), Gaps = 4/392 (1%)
Frame = +1
Query: 4576 ELEKAKR---SLEAELNDMR-VQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
EL+K K S E ++++M VQM ++ +Q+ E + +E+ +A E ++NK
Sbjct: 853 ELQKIKDLQVSSEQKVSEMENVQMMLQQEKMQLQEQLQAEIELCAEA--EEMRARLANKK 910
Query: 4744 VEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYX 4923
E EE + DLE+ +E E+ + +KK++ I ELE+QLE
Sbjct: 911 QELEEI-------LHDLESRVEEEEERCQILQTEKKKMQQNIVELEEQLEE--------- 954
Query: 4924 XXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARK 5103
EEA + K + + EA K + +E + L + N L
Sbjct: 955 -----------------EEAARQKLQLEKVTAEA--KMKKLEEDVLVLEDQNTKL----- 990
Query: 5104 QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLE 5283
+EK+ E +IA+ + + + K + +
Sbjct: 991 --------------------GKEKKLYEERIAEFTTNLTEEEEKSKSLAKLKNKHETMIS 1030
Query: 5284 QITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLE 5463
+ L E Q+ E ++ LE + D +I EL++ + + Q+A E ++Q
Sbjct: 1031 DLEERLRREEKQRQELEKTRRKLEGDSTDLHDQIAELQAQI-AELKLQLAKKEEELQAAL 1089
Query: 5464 DQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLD 5643
+ E +K A + R LE ++ + + E E+ A +A++ + L+ +L+
Sbjct: 1090 ARAEEEAAQKNLALKKIRELESQIGELQEDLESERAARNKAEKQKRDLGEELEALKTELE 1149
Query: 5644 EAEDEMSRERTKHRNVQREADDLLDANEQLTR 5739
+ D + ++ ++E L E R
Sbjct: 1150 DTLDSTATQQELRTKREQEVTHLKKTLEDEAR 1181
Score = 49.3 bits (116), Expect = 0.001
Identities = 62/296 (20%), Positives = 120/296 (39%), Gaps = 14/296 (4%)
Frame = +1
Query: 4897 ANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRA-VEAEREQLRE 5073
ANR EE + Q+ E+ E++ +L++ + + ++AE E E
Sbjct: 840 ANRFDEELHAKEVELQKIK-DLQVSSEQKVSEMENVQMMLQQEKMQLQEQLQAEIELCAE 898
Query: 5074 ANEGLMQAR----KQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCE 5241
A E M+AR KQ R + EE+R + + + +
Sbjct: 899 AEE--MRARLANKKQELEEILHDLESR-----VEEEEERCQILQTEKKKMQQNIVELEEQ 951
Query: 5242 LAIDKQRKAQVQLEQITTDLSMERT---------LNQKTEAEKQSLERSNRDYKAKITEL 5394
L ++ + ++QLE++T + M++ N K EK+ E ++ +TE
Sbjct: 952 LEEEEAARQKLQLEKVTAEAKMKKLEEDVLVLEDQNTKLGKEKKLYEERIAEFTTNLTEE 1011
Query: 5395 ESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRA 5574
E ++S A+ + E + LE++L E +++ + R+LE D+T +
Sbjct: 1012 EEKSKSLAKLKNKH-ETMISDLEERLRREEKQRQELEKTRRKLE---GDSTDLHDQIAEL 1067
Query: 5575 NEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
Q EL + K L+ L AE+E +++ + ++ + + E L E
Sbjct: 1068 QAQIAELKLQLAKKEEELQAALARAEEEAAQKNLALKKIRELESQIGELQEDLESE 1123
Score = 37.7 bits (86), Expect = 3.4
Identities = 35/170 (20%), Positives = 74/170 (42%), Gaps = 6/170 (3%)
Frame = +1
Query: 5254 KQRKAQVQLEQITTDLSM---ERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARA 5424
+Q K Q+Q EQ+ ++ + + + +KQ LE D ++++ E E Q +
Sbjct: 879 QQEKMQLQ-EQLQAEIELCAEAEEMRARLANKKQELEEILHDLESRVEEEEERCQI-LQT 936
Query: 5425 QMAALEAKVQYLEDQLNVEG---QEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKEL 5595
+ ++ + LE+QL E Q+ A K+L + ED+ + K+L
Sbjct: 937 EKKKMQQNIVELEEQLEEEEAARQKLQLEKVTAEAKMKKLEEDVLVLEDQNTKLGKEKKL 996
Query: 5596 LEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
E+ + + +E +++ + KH + + ++ L E+ +EL
Sbjct: 997 YEERIAEFTTNLTEEEEKSKSLAKLKNKHETMISDLEERLRREEKQRQEL 1046
>gi|9229910|dbj|BAB00612.1| myosin [Mizuhopecten yessoensis]
Length = 1154
Score = 1256 bits (3249), Expect = 0.0
Identities = 642/1146 (56%), Positives = 804/1146 (70%), Gaps = 20/1146 (1%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
+L+YL V R + DP A WA ++L WVP + GF S+ E DE+ VEL D+ + V
Sbjct: 13 ELKYLAVDRNRINDPMVQAEWAAKRLIWVPHEVHGFCAASVVSEKGDELEVELDDSGKHV 72
Query: 187 TIS--------------------RDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRY 306
++ RDD QK NPPKF K+EDM+ELT LNEASVLHNLKDRY
Sbjct: 73 KVTGDDWSENEPPLSFPKHVKVHRDDCQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRY 132
Query: 307 YSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQER 486
YS LIYTYSGLFCVV+NPYK+LPIY+E +I+ +K KKRHE+PPH+FAI D AYRSMLQ+R
Sbjct: 133 YSGLIYTYSGLFCVVVNPYKRLPIYTEKVIDLYKCKKRHEVPPHVFAITDAAYRSMLQDR 192
Query: 487 EDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELE 666
EDQ+ILCTGESGAGKTENTKKVIQYLAHVA + R ++ +Q +V GELE
Sbjct: 193 EDQAILCTGESGAGKTENTKKVIQYLAHVAASNRPSGNRSSVSNLHIQGSNVFTQ-GELE 251
Query: 667 HQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQA 846
+QLLQANPILEAFGN+KT+KNDNSSRFGKFI NFD SGYISGANIE YLLEKSR +RQA
Sbjct: 252 NQLLQANPILEAFGNAKTIKNDNSSRFGKFI--NFDSSGYISGANIETYLLEKSRAIRQA 309
Query: 847 QDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRI 1026
+ ER FHIFYQ L G + ++ E+LLE + NY FL + + + VDD EF T+ ++ I
Sbjct: 310 EQERCFHIFYQFLYGATPHQRKEFLLEDIGNYHFLTHGSVPVGGVDDTGEFRQTVEALTI 369
Query: 1027 MGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKA 1206
MG + ++ S+IMRV+S+VLL GN+ F QE+ SDQA L DD V QK CHLLGL V + +A
Sbjct: 370 MGISPEDQSAIMRVISSVLLFGNMTFRQERSSDQATLPDDTVAQKACHLLGLSVTSVIQA 429
Query: 1207 FLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFI 1386
FLRP+IKVGR+ V KAQ +EQ EFAV+A++KA YE+LFKWLV RIN+SLDRT RQGAS I
Sbjct: 430 FLRPKIKVGRDHVTKAQTKEQVEFAVQALSKACYEKLFKWLVIRINRSLDRTKRQGASLI 489
Query: 1387 GILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDL 1566
GILDIAGFEIF +NSFEQ+CI +EKLQQLFN+TMFILEQEEYQ+EGIEW FIDFGLDL
Sbjct: 490 GILDIAGFEIFKMNSFEQLCITTPSEKLQQLFNHTMFILEQEEYQKEGIEWKFIDFGLDL 549
Query: 1567 QPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTHNKHPKFIVPDMRSKSHFAVVH 1746
QPTIDL+EKPMG+ AL+DEEC FPKA DK+F++K+ H+ HP ++H
Sbjct: 550 QPTIDLLEKPMGIYALVDEECFFPKATDKTFIDKVVTQHSSHPSSRSLTSELMLTSGLIH 609
Query: 1747 YAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGM 1926
YAG+VDYSA WLMKNMDPLNENVV L+Q S+DPFV IWKDAE + AA +T FG
Sbjct: 610 YAGKVDYSAKMWLMKNMDPLNENVVSLLQTSSDPFVVAIWKDAEIVCMGAASTGDTMFGS 669
Query: 1927 RSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNG 2106
R+RKGMFRTVSQL+KEQL KLM TLRNT+P+FVRCIIPNHEKK+GKI+S LVLEQLRCNG
Sbjct: 670 RTRKGMFRTVSQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKIDSPLVLEQLRCNG 729
Query: 2107 VLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRI 2286
VLEGIRICRQGFPNR+ FQEFR RYEIL P IPK F+DGK+SV KMI AL++D NLYR+
Sbjct: 730 VLEGIRICRQGFPNRIIFQEFRQRYEILCPSSIPKGFMDGKKSVEKMINALELDPNLYRV 789
Query: 2287 GQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNG 2466
GQSK+FFR GVLAHLEEERDLKLT +I+ FQA CRG ++RR Y N
Sbjct: 790 GQSKIFFRAGVLAHLEEERDLKLTDIIIQFQALCRGLIARRNYQRRLQQLSAIRVIQRNC 849
Query: 2467 LAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLD 2646
+YLKLRNW WWRLFTKVKPLL V ++++ +DEL+ K+ + + D E E+K
Sbjct: 850 ASYLKLRNWAWWRLFTKVKPLLPVAGQEEKL-TLEDELKKFKDVNDRQKSDIEELERKYA 908
Query: 2647 QVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXX 2826
Q+I E++++ EQLQ E+E AE ++ + R+Q + +ELE I++D+ R+
Sbjct: 909 QIIEEKSILAEQLQAETEICAEAEESKARMQAKKEELEEILHDVEIRIEEEEDHCNALMD 968
Query: 2827 XRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXX 3006
R+K +TV D +K + D +D
Sbjct: 969 ERKKFQQTVADLEEQLEEEEQSRQKLQLEKVSADSKIKKYDEELALQEDTNHKLLKEKRA 1028
Query: 3007 XXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAE 3186
+T L++ EE+AK K K + E+ + +LE+ L +E Q + ELE+ +R+L +E
Sbjct: 1029 MEERMSEVTAHLVEEEEKAKQLGKLKNKYESIISDLEERLRKETQARQELEKIRRRLESE 1088
Query: 3187 LEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDEL 3366
L D ++ L EK ++E+L QL KR+EE+QH L + DEE + KQ R++Q+ + E+
Sbjct: 1089 LNDLREQLMEKRQQLEDLQAQLSKREEEVQHALKKVDEEGVAKSQASKQSREIQSQLQEV 1148
Query: 3367 REDMET 3384
ED+ET
Sbjct: 1149 TEDLET 1154
Score = 71.2 bits (173), Expect = 3e-10
Identities = 60/278 (21%), Positives = 129/278 (45%), Gaps = 37/278 (13%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEI-------ALLQASR 3738
+E+K ++++ D ++ K +LE++ Q +E++ +A+++ A + S+
Sbjct: 876 QEEKLTLEDELKKFKDVNDRQKSDIEELERKYAQIIEEKSILAEQLQAETEICAEAEESK 935
Query: 3739 ADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
A + K++ E L +++ + E ++H L+D+ ++ + + L EEEE + +Q
Sbjct: 936 ARMQAKKEELEEILHDVEIRIEEEEDHCNALMDERKKFQQTVADLEEQLEEEEQSRQKLQ 995
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNA----LLDEKEEA-------- 4062
+A + R +E+ + L++E+E+A
Sbjct: 996 LEKVSADSKIKKYDEELALQEDTNHKLLKEKRAMEERMSEVTAHLVEEEEKAKQLGKLKN 1055
Query: 4063 --EGLRAHLEKEIH---AARQGAGEARRKAEESVN----------QQLEELR---KKNLR 4188
E + + LE+ + ARQ + RR+ E +N QQLE+L+ K
Sbjct: 1056 KYESIISDLEERLRKETQARQELEKIRRRLESELNDLREQLMEKRQQLEDLQAQLSKREE 1115
Query: 4189 DVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
+V+H K+++E VAK + + ++IQ +L++ + +LE
Sbjct: 1116 EVQHALKKVDEEGVAKSQASKQSREIQSQLQEVTEDLE 1153
Score = 71.2 bits (173), Expect = 3e-10
Identities = 81/333 (24%), Positives = 146/333 (43%), Gaps = 1/333 (0%)
Frame = +1
Query: 3814 EHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKI 3993
E K TL D+L++ +D V + ++ ++R+ A T +
Sbjct: 877 EEKLTLEDELKKFKD-------VNDRQKSDIEELERKYAQIIEEKSILAEQLQAETEI-- 927
Query: 3994 ANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELR 4173
+ E+ K + +KEE LE+ +H E R + EE L + R
Sbjct: 928 -----CAEAEESKARMQAKKEE-------LEEILHDV-----EIRIEEEEDHCNALMDER 970
Query: 4174 KKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFE 4353
KK + V L++QLEE E QS++K+Q LE V A + + KK++
Sbjct: 971 KKFQQTVADLEEQLEEEE-------QSRQKLQ---------LEKVSA-----DSKIKKYD 1009
Query: 4354 SQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQ 4533
++A + K L ++ AM +R + V + L E + + L + S+ +L+
Sbjct: 1010 EELALQEDTNHKLLKEKRAM----EERMSEVTAHLVEEEEKAKQLGKLKNKYESIISDLE 1065
Query: 4534 DSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQ-IAEDARLRLEVTNQALK 4710
+ + + + ELEK +R LE+ELND+R Q+ E L+ + R E ALK
Sbjct: 1066 ERLRKETQARQ---ELEKIRRRLESELNDLREQLMEKRQQLEDLQAQLSKREEEVQHALK 1122
Query: 4711 SESDRAISNKDVEAEEKRRGLLKQIRDLENELE 4809
+ ++ +A ++ R + Q++++ +LE
Sbjct: 1123 KVDEEGVAKS--QASKQSREIQSQLQEVTEDLE 1153
Score = 62.8 bits (151), Expect = 1e-07
Identities = 40/202 (19%), Positives = 98/202 (47%), Gaps = 4/202 (1%)
Frame = +1
Query: 3046 DHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMG 3225
+ E+ + + + + + +LE+ L E Q + +L+ K ++++ + LA +
Sbjct: 958 EEEDHCNALMDERKKFQQTVADLEEQLEEEEQSRQKLQLEKVSADSKIKKYDEELALQ-- 1015
Query: 3226 KVEELNNQLMKRDEELQHQLTRYD----EESANVTLMQKQMRDMQTTIDELREDMETERN 3393
E+ N++L+K ++ +++ EE + K ++ I +L E + E
Sbjct: 1016 --EDTNHKLLKEKRAMEERMSEVTAHLVEEEEKAKQLGKLKNKYESIISDLEERLRKETQ 1073
Query: 3394 ARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEG 3573
AR + E RR + ++L ++ +++K + LQ +S+++EEV + +++ EG
Sbjct: 1074 ARQELEKIRRRLESELNDLREQLMEKRQQLEDLQAQLSKREEEVQHALKKVDE-----EG 1128
Query: 3574 KIEEQKAKFSRQVEELHDQIEQ 3639
+ Q +K SR+++ ++ +
Sbjct: 1129 VAKSQASKQSREIQSQLQEVTE 1150
Score = 59.3 bits (142), Expect = 1e-06
Identities = 53/262 (20%), Positives = 114/262 (43%), Gaps = 15/262 (5%)
Frame = +1
Query: 4978 EARQAKEDIAALLREADRKFRAVEAEREQLREANEGL--MQARKQXXXXXXXXXXXRAKG 5151
+ + + A ++ E ++AE E EA E MQA+K+ R +
Sbjct: 899 DIEELERKYAQIIEEKSILAEQLQAETEICAEAEESKARMQAKKEELEEILHDVEIRIEE 958
Query: 5152 G----GISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTD------- 5298
+E+++ + +A +L ++Q + ++QLE+++ D
Sbjct: 959 EEDHCNALMDERKKFQQTVADLEE---------QLEEEEQSRQKLQLEKVSADSKIKKYD 1009
Query: 5299 --LSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQL 5472
L+++ N K EK+++E + A + E E A+ + + E+ + LE++L
Sbjct: 1010 EELALQEDTNHKLLKEKRAMEERMSEVTAHLVEEEEKAKQLGKLKNK-YESIISDLEERL 1068
Query: 5473 NVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAE 5652
E Q + + RRLE LND +Q ++++ E + L K + ++ +++DE
Sbjct: 1069 RKETQARQELEKIRRRLESELNDLREQLMEKRQQLEDLQAQLSKREEEVQHALKKVDEEG 1128
Query: 5653 DEMSRERTKHRNVQREADDLLD 5718
S+ + R +Q + ++ +
Sbjct: 1129 VAKSQASKQSREIQSQLQEVTE 1150
Score = 58.2 bits (139), Expect = 2e-06
Identities = 71/342 (20%), Positives = 146/342 (41%), Gaps = 16/342 (4%)
Frame = +1
Query: 4582 EKAKRSLEAEL------ND-MRVQMEELEDNL-QIAEDARLRLEVTNQALKSESDRAISN 4737
++ K +LE EL ND + +EELE QI E+ + E L++E++
Sbjct: 876 QEEKLTLEDELKKFKDVNDRQKSDIEELERKYAQIIEEKSILAE----QLQAETEICAEA 931
Query: 4738 KDVEA--EEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLK 4911
++ +A + K+ L + + D+E +E E+ + + RKK + + +LE+QL
Sbjct: 932 EESKARMQAKKEELEEILHDVEIRIEEEEDHCNALMDERKKFQQTVADLEEQL------- 984
Query: 4912 EEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLM 5091
EE Q+++ + AD K + + E + N L+
Sbjct: 985 ---------------------EEEEQSRQKLQLEKVSADSKIKKYDEELALQEDTNHKLL 1023
Query: 5092 QARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQ 5271
+EKR +E ++++ + + + K +
Sbjct: 1024 -------------------------KEKRAMEERMSEVTAHLVEEEEKAK----QLGKLK 1054
Query: 5272 VQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSR------ARAQMA 5433
+ E I +DL E L ++T+A +Q LE+ R ++++ +L + +AQ++
Sbjct: 1055 NKYESIISDL--EERLRKETQA-RQELEKIRRRLESELNDLREQLMEKRQQLEDLQAQLS 1111
Query: 5434 ALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFE 5559
E +VQ+ +++ EG K+ A++ +R ++ +L + T+ E
Sbjct: 1112 KREEEVQHALKKVDEEGVAKSQASKQSREIQSQLQEVTEDLE 1153
>gi|13786876|pdb|1I84|S Chain S, Cryo-Em Structure Of The Heavy
Meromyosin Subfragment Of Chicken Gizzard Smooth Muscle
Myosin With Regulatory Light Chain In The
Dephosphorylated State. Only C Alphas Provided For
Regulatory Light Chain. Only Backbone Atoms Provided For
S2 Fragment.
gi|13786879|pdb|1I84|V Chain V, Cryo-Em Structure Of The Heavy
Meromyosin Subfragment Of Chicken Gizzard Smooth Muscle
Myosin With Regulatory Light Chain In The
Dephosphorylated State. Only C Alphas Provided For
Regulatory Light Chain. Only Backbone Atoms Provided For
S2 Fragment
Length = 1184
Score = 1255 bits (3248), Expect = 0.0
Identities = 641/1173 (54%), Positives = 842/1173 (71%), Gaps = 8/1173 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
D ++L V + V +P A W+ +KL WVP + GF SIK E DEV VEL + ++V
Sbjct: 8 DEKFLFVDKNFVNNPLAQADWSAKKLVWVPSEKHGFEAASIKEEKGDEVTVELQENGKKV 67
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
T+S+DD+QK NPPKF K+EDM+ELT LNEASVLHNL++RY+S LIYTYSGLFCVVINPYK
Sbjct: 68 TLSKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVINPYK 127
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
+LPIYSE +I+ +KGKKRHEMPPHI+AIADTAYRSMLQ+REDQSILCTGESGAGKTENTK
Sbjct: 128 QLPIYSEKIIDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTK 187
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVIQYLA VA + + K +I Q P GELE QLLQANPILEAFGN+KTVK
Sbjct: 188 KVIQYLAVVASSHKGKK-----DTSITQGPSFS--YGELEKQLLQANPILEAFGNAKTVK 240
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
NDNSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFY ++ G S +
Sbjct: 241 NDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQAKDERTFHIFYYLIAGASEQM 300
Query: 907 KSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLL 1086
+++ LLEG +NY FL N + +P D + F T+ +M IMGF ++E +SI+RVVS+VL
Sbjct: 301 RNDLLLEGFNNYTFLSNGHVPIPAQQDDEMFQETLEAMTIMGFTEEEQTSILRVVSSVLQ 360
Query: 1087 LGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQE 1266
LGN+ F +E+ +DQA + D+ QKVCHL+G+ V + ++ L PRIKVGR+ V KAQ +E
Sbjct: 361 LGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKE 420
Query: 1267 QAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQIC 1446
QA+FA+EA+AKA +ERLF+W++TR+NK+LD+T RQGASF+GILDIAGFEIF+INSFEQ+C
Sbjct: 421 QADFAIEALAKAKFERLFRWILTRVNKALDKTKRQGASFLGILDIAGFEIFEINSFEQLC 480
Query: 1447 INYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALL 1617
INYTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP I+LIE+P GVLALL
Sbjct: 481 INYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPTNPPGVLALL 540
Query: 1618 DEECLFPKANDKSFVEKLQKTHNKHPKF-IVPDMRSKSHFAVVHYAGRVDYSADQWLMKN 1794
DEEC FPKA D SFVEKL + H KF ++ K+ F ++HYAG+V Y+A WL KN
Sbjct: 541 DEECWFPKATDTSFVEKLIQEQGNHAKFQKSKQLKDKTEFCILHYAGKVTYNASAWLTKN 600
Query: 1795 MDPLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQ 1962
MDPLN+NV L+ S+D FVA +WKD + G+ A+M E++ +++KGMFRTV Q
Sbjct: 601 MDPLNDNVTSLLNQSSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQ 660
Query: 1963 LHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGF 2142
L+KEQLTKLMTTLRNT+P+FVRCIIPNHEK++GK++++LVLEQLRCNGVLEGIRICRQGF
Sbjct: 661 LYKEQLTKLMTTLRNTNPNFVRCIIPNHEKRAGKLDAHLVLEQLRCNGVLEGIRICRQGF 720
Query: 2143 PNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVL 2322
PNR+ FQEFR RYEIL + IPK F+DGK++ MI AL++D NLYRIGQSK+FFRTGVL
Sbjct: 721 PNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVL 780
Query: 2323 AHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWW 2502
AHLEEERDLK+T +I+ FQAQCRG+L+R+ + N +++ + +W W
Sbjct: 781 AHLEEERDLKITDVIIAFQAQCRGYLARKAFAKRQQQLESIFCIQYNVRSFMNVXHWPWM 840
Query: 2503 RLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQ 2682
LF + PLL+VTR ++E++AKD+EL+ TKER K E + +E E+K Q+ E+ ++QE+
Sbjct: 841 XLFFXIXPLLKVTRQEEEMQAKDEELQRTKERQQKAEAELKELEQKHTQLCEEKNLLQEK 900
Query: 2683 LQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDX 2862
LQ E+E AE +++R RL + QELE I+++M R+ ++K + + D
Sbjct: 901 LQAETELYAEAEEMRVRLAAKKQELEEILHEMEARIEEEEERSQQLQAEKKKMQQQMLDL 960
Query: 2863 XXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQL 3042
+K D +D + LTT L
Sbjct: 961 EEQLEEEEAARQKLQLEKVTADGKIKKMEDDILIMEDQNNKLTKERKLLEERVSDLTTNL 1020
Query: 3043 LDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKM 3222
+ EE+AK+ K K + E+ + ELE L +E + + ELE+ KRKL E D + +AE
Sbjct: 1021 AEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKIKRKLEGESSDLHEQIAELQ 1080
Query: 3223 GKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARN 3402
++ EL QL K++EELQ L R ++E++ K++R++++ I +L+ED+E+E+ ARN
Sbjct: 1081 AQIAELKAQLAKKEEELQAALARLEDETSQKNNALKKIRELESHISDLQEDLESEKAARN 1140
Query: 3403 KAEMTRREVVAQLEKVKGDVLDKVDEATMLQDL 3501
KAE +R++ +LE +K ++ D +D Q+L
Sbjct: 1141 KAEKQKRDLSEELEALKTELEDTLDTTATQQEL 1173
Score = 90.9 bits (224), Expect = 3e-16
Identities = 81/342 (23%), Positives = 158/342 (45%), Gaps = 16/342 (4%)
Frame = +1
Query: 3328 KQMRDMQTTIDELREDMETERNARNKAEMTRREVV-AQLEKVKGDVLDKVDEATMLQDLM 3504
+Q +MQ +EL+ E ++ A +AE+ E QL + K + +K+ T L
Sbjct: 854 RQEEEMQAKDEELQRTKERQQKA--EAELKELEQKHTQLCEEKNLLQEKLQAETELYAEA 911
Query: 3505 SRKDEEVNATKRAIEQIQHTMEGKIEEQ----------KAKFSRQVEELHDQIEQHKKQR 3654
+ A K+ +E+I H ME +IEE+ K K +Q+ +L +Q+E+ + R
Sbjct: 912 EEMRVRLAAKKQELEEILHEMEARIEEEEERSQQLQAEKKKMQQQMLDLEEQLEEEEAAR 971
Query: 3655 SQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLI 3834
+L+ ++ AD + M +I +++ + K+RK+ E + ++ NLAE +E + L
Sbjct: 972 QKLQLEKVTADGKIKKMEDDILIMEDQNNKLTKERKLLEERVSDLTTNLAEEEEKAKNLT 1031
Query: 3835 DQLERSRDELDHLN-RVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRA 4011
+ + L R+++EE+ +R ++ I
Sbjct: 1032 KLKNKHESMISELEVRLKKEEK---------------------------SRQELEKIK-- 1062
Query: 4012 RQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRD 4191
R+LE E + L ++ E + A L+ ++ + A + E+ +Q+ L+K +R+
Sbjct: 1063 RKLEGESSDLHEQIAELQAQIAELKAQLAKKEEELQAALARLEDETSQKNNALKK--IRE 1120
Query: 4192 VE----HLQKQLEESEVAKERILQSKKKIQQELEDSSMELEN 4305
+E LQ+ LE + A+ + + K+ + +ELE ELE+
Sbjct: 1121 LESHISDLQEDLESEKAARNKAEKQKRDLSEELEALKTELED 1162
Score = 80.9 bits (198), Expect = 4e-13
Identities = 83/304 (27%), Positives = 139/304 (45%), Gaps = 11/304 (3%)
Frame = +1
Query: 4015 QLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAG-----------EARRKAEESVNQQL 4161
QL +EKN LL EK +AE + E E R A EAR + EE +QQL
Sbjct: 889 QLCEEKN-LLQEKLQAE-TELYAEAEEMRVRLAAKKQELEEILHEMEARIEEEEERSQQL 946
Query: 4162 EELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQ 4341
+ +KK + + L++QLEE E A+++ ++LE V A + +
Sbjct: 947 QAEKKKMQQQMLDLEEQLEEEEAARQK----------------LQLEKVTA-----DGKI 985
Query: 4342 KKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQ 4521
KK E + K +R + + + D T L E + ++L + S+
Sbjct: 986 KKMEDDILIMEDQNNKLTKERKLLEERVSDLTTN----LAEEEEKAKNLTKLKNKHESMI 1041
Query: 4522 QELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQ 4701
EL+ + ++ K+ ELEK KR LE E +D+ Q+ EL+ + + + E Q
Sbjct: 1042 SELEVRLKKEE---KSRQELEKIKRKLEGESSDLHEQIAELQAQIAELKAQLAKKEEELQ 1098
Query: 4702 ALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELE 4881
A + + S K+ A +K R L I DL+ +LE+EK ++ A ++ + ++ L+
Sbjct: 1099 AALARLEDETSQKN-NALKKIRELESHISDLQEDLESEKAARNKAEKQKRDLSEELEALK 1157
Query: 4882 QQLE 4893
+LE
Sbjct: 1158 TELE 1161
Score = 67.4 bits (163), Expect = 4e-09
Identities = 82/396 (20%), Positives = 157/396 (38%)
Frame = +1
Query: 4522 QELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQ 4701
+ELQ + + + ELE+ L E N ++ +++ + AE+ R+RL Q
Sbjct: 864 EELQRTKERQQKAEAELKELEQKHTQLCEEKNLLQEKLQAETELYAEAEEMRVRLAAKKQ 923
Query: 4702 ALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELE 4881
L+ + + ++E +E E+ + +KK++ Q+ +LE
Sbjct: 924 ELE----------------------EILHEMEARIEEEEERSQQLQAEKKKMQQQMLDLE 961
Query: 4882 QQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAERE 5061
+QLE EEA + K + + AD K + +E +
Sbjct: 962 EQLEE--------------------------EEAARQKLQLEKV--TADGKIKKMEDDIL 993
Query: 5062 QLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCE 5241
+ + N L + RK A+ EEK + K+ S E
Sbjct: 994 IMEDQNNKLTKERKLLEERVSDLTTNLAE-----EEEKAKNLTKLKNKHESMI---SELE 1045
Query: 5242 LAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRAR 5421
+ + K+ K++ +LE+I +K E E L + +A+I EL +
Sbjct: 1046 VRLKKEEKSRQELEKI----------KRKLEGESSDLHEQIAELQAQIAEL--------K 1087
Query: 5422 AQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLE 5601
AQ+A E ++Q +L E +K A + R LE ++D + E EK A +A++
Sbjct: 1088 AQLAKKEEELQAALARLEDETSQKNNALKKIRELESHISDLQEDLESEKAARNKAEKQKR 1147
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+ + L+ +L++ D + ++ + ++ DD
Sbjct: 1148 DLSEELEALKTELEDTLDTTATQQELRGSDYKDDDD 1183
>gi|26337053|dbj|BAC32210.1| unnamed protein product [Mus musculus]
Length = 998
Score = 1207 bits (3122), Expect = 0.0
Identities = 598/957 (62%), Positives = 743/957 (77%), Gaps = 8/957 (0%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL V RA + +PAT A W +KL W+P + GF SIK E DEV+VEL + ++ +
Sbjct: 12 RYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMV 71
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDM+ELT LNEASVLHNLKDRYYS LIYTYSGLFCVVINPYK L
Sbjct: 72 NKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNL 131
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYSE++IE ++GKKRHEMPPHI+AI+++AYR MLQ+REDQSILCTGESGAGKTENTKKV
Sbjct: 132 PIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKV 191
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
IQYLAHVA + + + + N GELE QLLQANPILE+FGN+KTVKND
Sbjct: 192 IQYLAHVASSHKGRKDH--------------NIPGELERQLLQANPILESFGNAKTVKND 237
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFYQ+L G KS
Sbjct: 238 NSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKS 297
Query: 913 EYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 1092
+ LLEG +NYRFL N I +P D F T+ +M IMGF+ +EI S+++VVS+VL G
Sbjct: 298 DLLLEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFG 357
Query: 1093 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA 1272
N+ F +E+ +DQA + ++ V QK+CHLLG+ V+E +A L PRIKVGR++V KAQ +EQA
Sbjct: 358 NISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQA 417
Query: 1273 EFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICIN 1452
+FAVEA+AKA+YERLF+WLV RINK+LDRT RQGASFIGILDIAGFEIF++NSFEQ+CIN
Sbjct: 418 DFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCIN 477
Query: 1453 YTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDE 1623
YTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP IDLIE+P GVLALLDE
Sbjct: 478 YTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDE 537
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMD 1800
EC FPKA DK+FVEKL + H KF P ++ K+ F ++HYAG+VDY AD+WLMKNMD
Sbjct: 538 ECWFPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMD 597
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAFG--MRSRKGMFRTVSQLH 1968
PLN+NV L+ S+D FVA +WKD + G+ M ETAFG +++KGMFRTV QL+
Sbjct: 598 PLNDNVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLY 657
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
KE LTKLM TLRNT+P+FVRCIIPNHEK++GK++ +LVL+QLRCNGVLEGIRICRQGFPN
Sbjct: 658 KESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPN 717
Query: 2149 RVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAH 2328
R+ FQEFR RYEILTP+ IPK F+DGK++ +MI AL++D NLYRIGQSK+FFR GVLAH
Sbjct: 718 RIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAH 777
Query: 2329 LEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRL 2508
LEEERDLK+T +I+ FQA CRG+L+R+ + N AYLKLR+WQWWR+
Sbjct: 778 LEEERDLKITDVIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRV 837
Query: 2509 FTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQ 2688
FTKVKPLLQVTR ++E++AKD+EL KE+ K+E + E E+K Q++ E+ ++ EQLQ
Sbjct: 838 FTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQ 897
Query: 2689 QESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRD 2859
E+E AE +++R RL + QELE I++D+ R+ ++K ++D
Sbjct: 898 AETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQD 954
Score = 47.4 bits (111), Expect = 0.004
Identities = 35/162 (21%), Positives = 77/162 (46%), Gaps = 1/162 (0%)
Frame = +1
Query: 3247 QLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRRE 3426
Q+ +++EELQ + DEE V Q ++ ++ + + E+N + E
Sbjct: 846 QVTRQEEELQAK----DEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETE 901
Query: 3427 VVAQLEKVKGDVLDKVDE-ATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFS 3603
+ A+ E+++ + K E +L DL SR +EE + ++ +K K
Sbjct: 902 LFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQ------------ILQNEKKKMQ 949
Query: 3604 RQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQ 3729
+++L +Q+++ + R +L+ ++ A+ + M +E+ LL+
Sbjct: 950 AHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEVLLLE 991
Score = 42.0 bits (97), Expect = 0.18
Identities = 49/231 (21%), Positives = 105/231 (45%), Gaps = 29/231 (12%)
Frame = +1
Query: 4066 GLRAHLEKE---------IHAARQGAGEARRKAEESVNQQLEELR--KKN---------- 4182
G+ AHLE+E I G RKA QQL L+ ++N
Sbjct: 773 GVLAHLEEERDLKITDVIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHW 832
Query: 4183 --------LRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKR 4338
++ + + +Q EE + E +L+ K+K Q ++E ELE + H+ +
Sbjct: 833 QWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEK-QTKVEG---ELEEMERKHQQLLEE 888
Query: 4339 QKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSL 4518
++ +AE+ A + + + M L ++ + +L++++ E EE +++ ++
Sbjct: 889 ----KNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNE 944
Query: 4519 QQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAED 4671
++++Q I D + + E E A++ L+ E +++++E+ + + ED
Sbjct: 945 KKKMQAHI---QDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEVLLLED 992
Score = 41.2 bits (95), Expect = 0.31
Identities = 37/133 (27%), Positives = 63/133 (46%), Gaps = 7/133 (5%)
Frame = +1
Query: 5326 KTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQ-----E 5490
+ E E Q+ + K K T++E + R LE K L +QL E + E
Sbjct: 849 RQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEK-NILAEQLQAETELFAEAE 907
Query: 5491 KTAANRAARR--LEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMS 5664
+ A AA++ LE+ L+D + E+E+ N+ + +K ++L QLD E+E +
Sbjct: 908 EMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLD--EEEGA 965
Query: 5665 RERTKHRNVQREA 5703
R++ + V EA
Sbjct: 966 RQKLQLEKVTAEA 978
Score = 37.7 bits (86), Expect = 3.4
Identities = 21/75 (28%), Positives = 41/75 (54%)
Frame = +1
Query: 3052 EERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKV 3231
E RA+ K K LE LH+LE + E + L+ K+K+ A ++D ++ L E+ G
Sbjct: 908 EMRARLAAK-KQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGAR 966
Query: 3232 EELNNQLMKRDEELQ 3276
++L + + + +++
Sbjct: 967 QKLQLEKVTAEAKIK 981
Score = 37.0 bits (84), Expect = 5.8
Identities = 31/134 (23%), Positives = 59/134 (43%), Gaps = 3/134 (2%)
Frame = +1
Query: 4501 RVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQI---AED 4671
R LQ + ++ + K+ K ELE+ +R + L + + E+L+ ++ AE+
Sbjct: 849 RQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEE 908
Query: 4672 ARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRK 4851
R RL Q L+ + + DLE+ +E E+ + +K
Sbjct: 909 MRARLAAKKQELE----------------------EILHDLESRVEEEEERNQILQNEKK 946
Query: 4852 KIENQIGELEQQLE 4893
K++ I +LE+QL+
Sbjct: 947 KMQAHIQDLEEQLD 960
>gi|3986194|dbj|BAA34954.1| myosin heavy chain [Dugesia japonica]
Length = 1958
Score = 1203 bits (3113), Expect = 0.0
Identities = 685/1941 (35%), Positives = 1105/1941 (56%), Gaps = 28/1941 (1%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
D QYL V R A+ ++ +K CW+PD+ EGF+ +I+ + D ++ +
Sbjct: 7 DFQYLGVDRKALLKQYG-DSFDSKKNCWIPDEKEGFISATIEDSSGDVFTIK-TEKLETK 64
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
T+ +D++Q+ NPPKF IEDM+ LT+LN+ASVL NL+ R+Y +LIYTYSGLFCV INPYK
Sbjct: 65 TVKKDEIQQMNPPKFMMIEDMANLTFLNDASVLDNLRQRFYKNLIYTYSGLFCVTINPYK 124
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
+ PIY+ +I ++KGK+R EMPPHIF+I+D AY +ML +R++QS+L TGESGAGKTENTK
Sbjct: 125 RFPIYTAQVIAKYKGKRRTEMPPHIFSISDNAYSNMLTDRDNQSVLITGESGAGKTENTK 184
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVI Y AHVA AT+ + + + G LE Q++QANP+LEA+GN+KTV+
Sbjct: 185 KVITYFAHVAAATKKEDDESGSGGKRK---------GTLEDQIVQANPVLEAYGNAKTVR 235
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
N+NSSRFGKFIRI+F SG I+GA+IEFYLLEKSRV Q + ER++HIFYQIL K+
Sbjct: 236 NNNSSRFGKFIRIHFGTSGKIAGADIEFYLLEKSRVNSQQKGERNYHIFYQIL-SAGGKQ 294
Query: 907 KSEYLLEGVDN--YRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAV 1080
E LL D Y F+ +T+ VDD +E T + I+GF+ DE S+ + ++
Sbjct: 295 FHEKLLISPDPALYSFINQGELTIDGVDDEEEMKITDEAFDILGFSSDEKMSLFKCTCSI 354
Query: 1081 LLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQN 1260
L +G ++F Q + +QA +KV LLG+ +L ++ L+P++KVG E+V K Q+
Sbjct: 355 LNMGEMKFKQRPREEQAEADGTAEAEKVAFLLGVNAKDLMQSILKPKVKVGNEYVTKGQS 414
Query: 1261 QEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQ 1440
++Q ++V A+AK+ Y R+F WLV R+NK+LD T + FIG+LDIAGFEIF+ N FEQ
Sbjct: 415 KDQVLYSVGALAKSLYNRMFAWLVLRVNKTLD-TKVKRQFFIGVLDIAGFEIFNFNGFEQ 473
Query: 1441 ICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLD 1620
ICINYTNE+LQQ FN+ MF+LEQEEY++E I+W+FIDFG+DLQ I+LIEKPMG+L++L+
Sbjct: 474 ICINYTNERLQQFFNHHMFVLEQEEYKKEAIDWEFIDFGMDLQACIELIEKPMGILSILE 533
Query: 1621 EECLFPKANDKSFVEKLQKTH-NKHPKFIVPDM----RSKSHFAVVHYAGRVDYSADQWL 1785
EEC+FPKA+D +F KL H K P F P ++++HF + HYAG V Y+ WL
Sbjct: 534 EECMFPKASDMTFKAKLYDNHLGKSPNFGKPKPPKPGQAEAHFELHHYAGSVPYNVTGWL 593
Query: 1786 MKNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQL 1965
KN DPLNE V+ L+ S + V+ ++ AE A ++ G R + G +T+S
Sbjct: 594 EKNKDPLNETVINLLAASKEALVSSLFVPAEDA---------SSSGKRKKGGAMQTISST 644
Query: 1966 HKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFP 2145
H+E L KLM L++TSPHF+RCI+PN K+ G I+++LVL QL CNGVLEGIRICR+GFP
Sbjct: 645 HRESLNKLMKNLQSTSPHFIRCIVPNEFKQPGVIDAHLVLHQLHCNGVLEGIRICRKGFP 704
Query: 2146 NRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLA 2325
NR+ + EF+ RY IL P+ IP+ F++GK+ K++ A+ +D NLYR+G +K+FF+ G LA
Sbjct: 705 NRMIYSEFKQRYSILAPNAIPQGFVEGKQVTGKILEAVQLDKNLYRLGNTKIFFKAGTLA 764
Query: 2326 HLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWR 2505
LE+ RD KL++LI FQAQ RG+L R+ Y N YL LR W WW+
Sbjct: 765 DLEDMRDEKLSSLISLFQAQIRGYLMRKQYKKLQDQRVALSIIQRNIRKYLMLRTWAWWK 824
Query: 2506 LFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQL 2685
L+TKVKPLL + R ++E++ +EL KE K++ +E E++ +++ + + QL
Sbjct: 825 LYTKVKPLLNIARQEEEMKKAAEELAKLKEEFEKVDKFKKELEEQNVKLLEAKNDLFLQL 884
Query: 2686 QQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXX 2865
Q E ++ A+ ++ +L + ++E + ++ D L ++K + +
Sbjct: 885 QTEQDSLADAEEKVSKLVMQKADMESRIKELEDHLLEEEDASAGLEEMKKKMQGEIEELK 944
Query: 2866 XXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLL 3045
+KT DQ ++ + L
Sbjct: 945 KDVVDLESSLQKAEQEKTAKDQQIKALQDQIARQEEEMNKMKKEKKAADELQKKTEESLQ 1004
Query: 3046 DHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMG 3225
EE+ K+ KAK +LE + E+E++L+RE++ ++++E+ KRK+ EL+ +++ + +
Sbjct: 1005 AEEEKVKNLNKAKAKLEQTIDEMEENLSREQKVRADVEKVKRKIETELKQTQETVDDLER 1064
Query: 3226 KVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNK 3405
EL QL +++ EL + ++ ++ES V +QK+++++Q I EL ED+E ER AR K
Sbjct: 1065 VKRELEEQLKRKEMELSNASSKIEDESGLVAQLQKKIKELQARIQELEEDLEAERQARAK 1124
Query: 3406 AEMTRREVVAQLEKVKGDVLDKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIE 3582
AE +R ++ +LE++ D L++ AT Q +L +++ E+ KR +E+ + I
Sbjct: 1125 AEKSRHQLEGELEEL-SDRLEEQGGATSAQLELNKKREAELLKLKRDLEEANMQHDQMIA 1183
Query: 3583 EQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRK 3762
+ + K E DQ++Q +K ++++EK++N+ ++ D+ ++ L ++A+ DKK K
Sbjct: 1184 QSRKKQQDVANEFSDQLDQLQKAKAKIEKEKNEMKEDLNDLQSQLEALNKAKANSDKKIK 1243
Query: 3763 IHEAHLMEIQANLAESDEH--------------KRTLIDQLERSRDELDHLNRVREEEEH 3900
E+ E+Q L E + H L +LE + +++ L +V+++
Sbjct: 1244 ELESQNAELQGKLEELNRHINDANNTSGKNQQLNAELQARLEEAESQINQLTKVKQQ--- 1300
Query: 3901 AFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAH 4080
MQ +L A +R K + R L + + L + EE ++
Sbjct: 1301 ----MQTQLEEA-------RQNLDDESRTKAKLSSDVRNLNADLDNLREALEEENENKSD 1349
Query: 4081 LEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKK 4260
L++++ A+ + + K E + + + EEL + + + + + EESE AK ++ Q +K
Sbjct: 1350 LQRQLVKAQSEMQQMKSKFEGTGSVRSEELDEAKRKFMARIHELEEESESAKSKVGQLEK 1409
Query: 4261 ---KIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRD 4431
++Q E+ED ++++ A EK+QK F+ ++E + ++ + +A +E R
Sbjct: 1410 IKARLQGEIEDMLVDVDRANALASQLEKKQKTFDKVVSEWQQKYAESQAEVEASQRESRA 1469
Query: 4432 RETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAE 4611
V L +++ +E LE R ++L E+ D + G++VHE EKA++ LE E
Sbjct: 1470 VSAEVFRLKAQIEESQEQLESVKRENKNLADEIHDLTEQIGEGGRSVHETEKARKRLEME 1529
Query: 4612 LNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRD 4791
+++ +EE E L+ E R ++ ++ E DR I+ K+ E E R + +
Sbjct: 1530 KEELQHALEEAEQALEQEEAKAQRSQLEMSQVRQEIDRRIAEKEEEFEATRVNHQRAMES 1589
Query: 4792 LENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIE 4971
+E LE E RG++ + +KK+E+ IGELE ++ ANR + E E Q
Sbjct: 1590 MEASLEAESRGRTESTKMKKKLEHDIGELEVAVDTANRFRSEAEKNAKKFQQQVQELQAM 1649
Query: 4972 CEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKG 5151
E+ + K+ I +RK + E E++R + E + RK +
Sbjct: 1650 VEDEKHQKDQIREQTMMNERKMAMILGELEEVRSSLENSERNRKNTESEKVELTDRLNEL 1709
Query: 5152 GGISSE---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLN 5322
SS KR+LEA +A + A ++ +KA ++ ++ E+
Sbjct: 1710 SVQSSSFMATKRKLEADLAAMQSDLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHA 1769
Query: 5323 QKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAA 5502
Q+ + K+ LE N++ + K+ E E+ A + + LE +V+ LE +L+ E +
Sbjct: 1770 QQLDKIKKQLEAQNKELQVKLDESENNAMKGGKKVLGKLEQRVRELEAELDAEQKRHVET 1829
Query: 5503 NRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKH 5682
+ R++E+RL + Q +++K+ E+ ++L+EK K + +RQ++EAE+ + K+
Sbjct: 1830 QKNTRKIERRLKEIGLQTDEDKKNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKY 1889
Query: 5683 RNVQREADDLLDANEQLTREL 5745
R +Q+E +D + +Q + L
Sbjct: 1890 RKIQQEIEDSEERADQAEQAL 1910
Score = 189 bits (481), Expect = 5e-46
Identities = 187/932 (20%), Positives = 392/932 (41%), Gaps = 49/932 (5%)
Frame = +1
Query: 2515 KVKPLLQVTRTD-DEIRAKDDELRATKERLL-KMEHDFRENEKKLDQVIVERAVIQEQLQ 2688
K K L+ T + +E +++ ++RA E++ K+E + ++ ++ +D + + ++EQL+
Sbjct: 1015 KAKAKLEQTIDEMEENLSREQKVRADVEKVKRKIETELKQTQETVDDLERVKRELEEQLK 1074
Query: 2689 QE----SENSAELDDIRG---RLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQME 2847
++ S S++++D G +LQ + +EL+ + ++ + L R +
Sbjct: 1075 RKEMELSNASSKIEDESGLVAQLQKKIKELQARIQELEEDLEAERQARAKAEKSRHQLEG 1134
Query: 2848 TVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXG 3027
+ + + +D
Sbjct: 1135 ELEELSDRLEEQGGATSAQLELNKKREAELLKLKRDLEEANMQHDQMIAQSRKKQQDVAN 1194
Query: 3028 LTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDH 3207
+ LD + KAK ++E + +E+++DLN + L + K ++++ +
Sbjct: 1195 EFSDQLDQLQ------KAKAKIEKEKNEMKEDLNDLQSQLEALNKAKANSDKKIKELESQ 1248
Query: 3208 LAEKMGKVEELN------NQLMKRDEELQHQL-TRYDEESANVTLMQKQMRDMQTTIDEL 3366
AE GK+EELN N ++++L +L R +E + + + K + MQT ++E
Sbjct: 1249 NAELQGKLEELNRHINDANNTSGKNQQLNAELQARLEEAESQINQLTKVKQQMQTQLEEA 1308
Query: 3367 REDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAI 3546
R++++ E + K R + A L+ ++ + ++ + + LQ + + E+ K
Sbjct: 1309 RQNLDDESRTKAKLSSDVRNLNADLDNLREALEEENENKSDLQRQLVKAQSEMQQMKSKF 1368
Query: 3547 EQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALL 3726
E +++E K KF ++ EL ++ E K + QLEK + + E DM ++
Sbjct: 1369 EGTGSVRSEELDEAKRKFMARIHELEEESESAKSKVGQLEKIKARLQGEIEDMLVDVDRA 1428
Query: 3727 QASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAF 3906
A + ++KK+K + + E Q AES + E+ L EE +
Sbjct: 1429 NALASQLEKKQKTFDKVVSEWQQKYAESQAEVEASQRESRAVSAEVFRLKAQIEESQEQL 1488
Query: 3907 ANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLE 4086
+++R R ++LE EK L EEAE E
Sbjct: 1489 ESVKRENKNLADEIHDLTEQIGEGGRSVHETEKARKRLEMEKEELQHALEEAEQALEQEE 1548
Query: 4087 KEIHAARQGAGEARRKAEESVNQQLEEL---RKKNLRDVEHLQKQLEESEVAKERILQSK 4257
+ ++ + R++ + + ++ EE R + R +E ++ LE + + K
Sbjct: 1549 AKAQRSQLEMSQVRQEIDRRIAEKEEEFEATRVNHQRAMESMEASLEAESRGRTESTKMK 1608
Query: 4258 KKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRE 4437
KK++ ++ + + ++ ++EK KKF+ Q+ E + V+ +D + ++ E
Sbjct: 1609 KKLEHDIGELEVAVDTANRFRSEAEKNAKKFQQQVQELQAMVEDEKHQKDQIREQTMMNE 1668
Query: 4438 TRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELN 4617
++ +L E++ ++ LE S+R R++ + E + ++ KR LEA+L
Sbjct: 1669 RKMAMILGELEEVRSSLENSERNRKNTESEKVELTDRLNELSVQSSSFMATKRKLEADLA 1728
Query: 4618 DMRVQMEELEDNLQ---------IAEDARL-------------------RLEVTNQALKS 4713
M+ +EE + + +A+ +RL +LE N+ L+
Sbjct: 1729 AMQSDLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQLDKIKKQLEAQNKELQV 1788
Query: 4714 ESDRAISNKDVEAEEKRRGLLKQ-IRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
+ D + N ++ +K G L+Q +R+LE EL+ E++ + +KIE ++ E+ Q
Sbjct: 1789 KLDES-ENNAMKGGKKVLGKLEQRVRELEAELDAEQKRHVETQKNTRKIERRLKEIGLQT 1847
Query: 4891 EVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKF-RAVEAEREQL 5067
+ + +E Y+ + EEA E+IAA+ RK + +E E+
Sbjct: 1848 DEDKKNQERLQDLVEKLQGKIKTYKRQVEEA----EEIAAVNLAKYRKIQQEIEDSEERA 1903
Query: 5068 REANEGLMQARKQXXXXXXXXXXXRAKGGGIS 5163
+A + L + R + A+GG ++
Sbjct: 1904 DQAEQALQKLRTKNRSSVST-----ARGGSMA 1930
>gi|28277520|gb|AAH45324.1| Wu:fi22c04 protein [Danio rerio]
Length = 1046
Score = 1203 bits (3113), Expect = 0.0
Identities = 610/1050 (58%), Positives = 760/1050 (72%), Gaps = 7/1050 (0%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
++L R + DP A WA +KL WVP + GF GSIK ET DE LVEL D+ +++ +
Sbjct: 6 KFLYADRNTINDPLAQADWATKKLVWVPSEKLGFEAGSIKEETGDECLVELADSGKKIKV 65
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDM+ELT LNEASVLHNL++RYYS LIYTYSGLFCVVINPYK L
Sbjct: 66 NKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKYL 125
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIY+E ++E +KGKKRHEMPPHI+AI DTAYRSM+Q+REDQSILCTGESGAGKTENTKKV
Sbjct: 126 PIYTEKIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKV 185
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
IQYLA+VA + + K + + GELE QLLQANPILEAFGN+KTVKND
Sbjct: 186 IQYLAYVASSFKTKK----------DQSSIALSHGELEKQLLQANPILEAFGNAKTVKND 235
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFY +L G K +S
Sbjct: 236 NSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKDERAFHIFYYLLTGAGDKLRS 295
Query: 913 EYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 1092
E LE + YRFL N +T+P D + F TI++ RIMG +DE + +++VVSAVL LG
Sbjct: 296 ELCLEDYNKYRFLSNGNVTIPGQQDRELFAETIDAFRIMGIPEDEQTGLLKVVSAVLQLG 355
Query: 1093 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA 1272
N+ F +E+ SDQA + DD QKV HLLG+ V + +A L PRIKVGR+FV KAQ QEQA
Sbjct: 356 NMSFKKERNSDQASMPDDTAAQKVSHLLGMNVTDFTRAILSPRIKVGRDFVQKAQTQEQA 415
Query: 1273 EFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICIN 1452
EFAVEA+AKA+YERLF+WLV RINK+LD+T RQGASFIGILDIAGFEIF++NSFEQ+CIN
Sbjct: 416 EFAVEALAKATYERLFRWLVMRINKALDKTKRQGASFIGILDIAGFEIFELNSFEQLCIN 475
Query: 1453 YTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEK---PMGVLALLDE 1623
YTNEKLQQLFN+TMFILEQEEYQREGIEW FIDFGLDLQP I+LIEK P G+LALLDE
Sbjct: 476 YTNEKLQQLFNHTMFILEQEEYQREGIEWSFIDFGLDLQPCIELIEKPNGPPGILALLDE 535
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMD 1800
EC FPKA DKSFVEK+ + +PKF P ++ + F ++HYAG+VDY A++WLMKNMD
Sbjct: 536 ECWFPKATDKSFVEKVVQELGNNPKFQKPKKLKDDADFCIIHYAGKVDYKANEWLMKNMD 595
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAFG-MRSRKGMFRTVSQLHK 1971
PLN+NV L+ S D FV+ +WKD + G+ A M E+ G +++RKGMFRTV QL+K
Sbjct: 596 PLNDNVATLLNQSVDKFVSELWKDVDRIVGLDKVAGMGESLHGAVKTRKGMFRTVGQLYK 655
Query: 1972 EQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNR 2151
EQL LMTTLRNT+P+FVRCIIPNHEKK+GK+ +LVL+QLRCNGVLEGIRICRQGFPNR
Sbjct: 656 EQLMNLMTTLRNTNPNFVRCIIPNHEKKAGKLAHHLVLDQLRCNGVLEGIRICRQGFPNR 715
Query: 2152 VPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHL 2331
+ FQEFR RYEILTP+ IPK F+DGK++ M+ AL++D+NLYRIGQSKVFFR GVLAHL
Sbjct: 716 IVFQEFRQRYEILTPNAIPKGFMDGKQACVLMVKALELDSNLYRIGQSKVFFRAGVLAHL 775
Query: 2332 EEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLF 2511
EEERD+K+T +I+NFQA CRG+++RR + N AYLKLRNWQWWRLF
Sbjct: 776 EEERDMKITDVIINFQAWCRGYVARRAFAKRQQQLTAMRVIQRNCAAYLKLRNWQWWRLF 835
Query: 2512 TKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQ 2691
TKVKPLLQVTR ++E+ AK++EL KER + E +E+E K Q+ E+ +QEQLQ
Sbjct: 836 TKVKPLLQVTRQEEEMVAKEEELVKMKERQQQAEDQLKESEAKQKQLNAEKLALQEQLQA 895
Query: 2692 ESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXX 2871
E+E E +++R RL R QE+E +++++ RL ++K + + D
Sbjct: 896 ETELCQEAEEMRSRLTARMQEMEEVLHELESRLEEEEERVAQFQSEKKKMQQNIGDLEQQ 955
Query: 2872 XXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDH 3051
+K +D +D TT L +
Sbjct: 956 LDEEEAARQKLQLEKVTMDAKLKKIEEDLMVIEDQNAKLSKEKKQMEERISEFTTNLAEE 1015
Query: 3052 EERAKHGVKAKGRLENQLHELEQDLNRERQ 3141
EE++K K K + E + +LE L ++++
Sbjct: 1016 EEKSKSLQKLKTKHETMITDLEDRLRKKKK 1045
Score = 70.1 bits (170), Expect = 6e-10
Identities = 56/213 (26%), Positives = 100/213 (46%), Gaps = 11/213 (5%)
Frame = +1
Query: 4216 EESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKAL 4395
EE VAKE L K+ QQ+ ED ++SE +QK Q+ E++A+Q+ L
Sbjct: 848 EEEMVAKEEELVKMKERQQQAEDQL----------KESEAKQK----QLNAEKLALQEQL 893
Query: 4396 LDRDAMSQELRDRETRVLSLLNEVD----IMKEHLEESDRVRRSLQQELQDSISNKDDFG 4563
+ QE + +R+ + + E++ ++ LEE + Q E + N D
Sbjct: 894 QAETELCQEAEEMRSRLTARMQEMEEVLHELESRLEEEEERVAQFQSEKKKMQQNIGDLE 953
Query: 4564 KNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
+ + E E A++ L+ E M +++++E++L + ED +L + ++ +N
Sbjct: 954 QQLDEEEAARQKLQLEKVTMDAKLKKIEEDLMVIEDQNAKLSKEKKQMEERISEFTTNL- 1012
Query: 4744 VEAEEKRRGLLK-------QIRDLENELENEKR 4821
E EEK + L K I DLE+ L +K+
Sbjct: 1013 AEEEEKSKSLQKLKTKHETMITDLEDRLRKKKK 1045
Score = 48.9 bits (115), Expect = 0.001
Identities = 38/195 (19%), Positives = 93/195 (47%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDE 3267
RL ++ L Q +E + ++ E+ K+ + ++D L E K ++LN + + E
Sbjct: 833 RLFTKVKPLLQVTRQEEEMVAK-EEELVKMKERQQQAEDQLKESEAKQKQLNAEKLALQE 891
Query: 3268 ELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEK 3447
+LQ + E + + +M++M+ + EL +E E + + ++++ +
Sbjct: 892 QLQAETELCQEAEEMRSRLTARMQEMEEVLHELESRLEEEEERVAQFQSEKKKMQQNI-- 949
Query: 3448 VKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
GD+ ++DE + + + ++A + IE+ IE+Q AK S++ +++ +
Sbjct: 950 --GDLEQQLDEEEAARQKLQLEKVTMDAKLKKIEEDLMV----IEDQNAKLSKEKKQMEE 1003
Query: 3628 QIEQHKKQRSQLEKQ 3672
+I + ++ E++
Sbjct: 1004 RISEFTTNLAEEEEK 1018
Score = 47.8 bits (112), Expect = 0.003
Identities = 51/222 (22%), Positives = 98/222 (43%), Gaps = 7/222 (3%)
Frame = +1
Query: 4015 QLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKK----- 4179
++++ + D+ +E+E + L E A ++ + +AE + Q+ EE+R +
Sbjct: 860 KMKERQQQAEDQLKESEAKQKQLNAEKLALQE-----QLQAETELCQEAEEMRSRLTARM 914
Query: 4180 -NLRDVEH-LQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFE 4353
+ +V H L+ +LEE E + KKK+QQ + D E
Sbjct: 915 QEMEEVLHELESRLEEEEERVAQFQSEKKKMQQNIGD---------------------LE 953
Query: 4354 SQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQ 4533
Q+ EE A QK L++ M +L+ E D+M +E+ + +++++
Sbjct: 954 QQLDEEEAARQKLQLEKVTMDAKLKKIEE---------DLMV--IEDQNAKLSKEKKQME 1002
Query: 4534 DSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQ 4659
+ IS +F N+ E E+ +SL+ + +LED L+
Sbjct: 1003 ERIS---EFTTNLAEEEEKSKSLQKLKTKHETMITDLEDRLR 1041
Score = 47.0 bits (110), Expect = 0.006
Identities = 34/104 (32%), Positives = 57/104 (54%), Gaps = 7/104 (6%)
Frame = +1
Query: 4603 EAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQ 4782
E EL M+ + ++ ED L+ +E + +L AL+ E +A + EAEE R L +
Sbjct: 855 EEELVKMKERQQQAEDQLKESEAKQKQLNAEKLALQ-EQLQAETELCQEAEEMRSRLTAR 913
Query: 4783 IRD-------LENELENEKRGKSGAVSHRKKIENQIGELEQQLE 4893
+++ LE+ LE E+ + S +KK++ IG+LEQQL+
Sbjct: 914 MQEMEEVLHELESRLEEEEERVAQFQSEKKKMQQNIGDLEQQLD 957
Score = 44.3 bits (103), Expect = 0.036
Identities = 26/126 (20%), Positives = 62/126 (48%)
Frame = +1
Query: 3028 LTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDH 3207
L ++L + EER K +++ + +LEQ L+ E + +L+ K + A+L+
Sbjct: 924 LESRLEEEEERVAQFQSEKKKMQQNIGDLEQQLDEEEAARQKLQLEKVTMDAKLK----K 979
Query: 3208 LAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETE 3387
+ E + +E+ N +L K ++++ +++ + A K ++ ++T + + D+E
Sbjct: 980 IEEDLMVIEDQNAKLSKEKKQMEERISEFTTNLAEEEEKSKSLQKLKTKHETMITDLEDR 1039
Query: 3388 RNARNK 3405
+ K
Sbjct: 1040 LRKKKK 1045
Score = 43.9 bits (102), Expect = 0.047
Identities = 35/181 (19%), Positives = 83/181 (45%), Gaps = 21/181 (11%)
Frame = +1
Query: 3037 QLLDHEERAKHGVKAKGRLENQLHELE---QDLNRERQYKSELEQHKRKLLAELEDSKDH 3207
+++ EE + + + E+QL E E + LN E+ E Q + +L E E+ +
Sbjct: 850 EMVAKEEELVKMKERQQQAEDQLKESEAKQKQLNAEKLALQEQLQAETELCQEAEEMRSR 909
Query: 3208 LAEKMGKVEELNNQLMKRDEELQHQLTRY------------------DEESANVTLMQKQ 3333
L +M ++EE+ ++L R EE + ++ ++ DEE A +Q +
Sbjct: 910 LTARMQEMEEVLHELESRLEEEEERVAQFQSEKKKMQQNIGDLEQQLDEEEAARQKLQLE 969
Query: 3334 MRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRK 3513
M + ++ ED+ + K ++++ ++ + ++ ++ +++ LQ L ++
Sbjct: 970 KVTMDAKLKKIEEDLMVIEDQNAKLSKEKKQMEERISEFTTNLAEEEEKSKSLQKLKTKH 1029
Query: 3514 D 3516
+
Sbjct: 1030 E 1030
Score = 40.8 bits (94), Expect = 0.40
Identities = 42/222 (18%), Positives = 95/222 (41%), Gaps = 6/222 (2%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLE------KQQNQADQERADMAQEIALLQASRA 3741
EE+ K + ++ DQ+++ + ++ QL ++Q QA+ E A+E+ R+
Sbjct: 855 EEELVKMKERQQQAEDQLKESEAKQKQLNAEKLALQEQLQAETELCQEAEEM------RS 908
Query: 3742 DIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQR 3921
+ + + E L E+++ L E +E + ++ + + L + +EEE A +Q
Sbjct: 909 RLTARMQEMEEVLHELESRLEEEEERVAQFQSEKKKMQQNIGDLEQQLDEEEAARQKLQL 968
Query: 3922 RLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHA 4101
T K+ I + +++NA L ++++ +E+ I
Sbjct: 969 EKVTMDA---------------KLKKIEEDLMVIEDQNAKLSKEKK------QMEERISE 1007
Query: 4102 ARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESE 4227
E EE ++ L++L+ K+ + L+ +L + +
Sbjct: 1008 FTTNLAE-----EEEKSKSLQKLKTKHETMITDLEDRLRKKK 1044
Score = 38.9 bits (89), Expect = 1.5
Identities = 47/201 (23%), Positives = 92/201 (45%), Gaps = 12/201 (5%)
Frame = +1
Query: 5176 RRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQL-EQITTDLSMERTLNQKTEAEKQSL 5352
RR AK Q Q NC + + +L ++ L + R + E++ +
Sbjct: 800 RRAFAKRQQQLTAMRVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMVAKEEELV 859
Query: 5353 ERSNRDYKAKITELESGA-QSRARAQMAALEAKVQYLEDQLNVEGQE-KTAANRAARRLE 5526
+ R +A+ ES A Q + A+ AL+ ++Q E +L E +E ++ + +E
Sbjct: 860 KMKERQQQAEDQLKESEAKQKQLNAEKLALQEQLQ-AETELCQEAEEMRSRLTARMQEME 918
Query: 5527 KRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREA- 5703
+ L++ + E+E+ Q + +K +L +QLD E+E +R++ + V +A
Sbjct: 919 EVLHELESRLEEEEERVAQFQSEKKKMQQNIGDLEQQLD--EEEAARQKLQLEKVTMDAK 976
Query: 5704 -----DDLL---DANEQLTRE 5742
+DL+ D N +L++E
Sbjct: 977 LKKIEEDLMVIEDQNAKLSKE 997
>gi|11276951|pir||A59287 myosin heavy chain - fluke (Schistosoma
mansoni) (strain Brazilian LE)
gi|161044|gb|AAA29905.1| myosin heavy chain
Length = 1940
Score = 1197 bits (3096), Expect = 0.0
Identities = 670/1927 (34%), Positives = 1091/1927 (55%), Gaps = 14/1927 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
D +YL V R A+ LA + + + WV D+ EG+++ IK T D + V L D S +
Sbjct: 7 DFKYLGVDRKALLKE--LANFDSKNVIWVEDEKEGYVLADIKDTTGDTITVALKDGSEK- 63
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
+ +DD Q+ NPPKF IEDM+ LT+LN+ASVL NL+ RYY LIYTYSGLFCV +NPYK
Sbjct: 64 KVKKDDAQQVNPPKFFLIEDMANLTHLNDASVLENLRARYYRQLIYTYSGLFCVAVNPYK 123
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
+ PIY+E + ++KGK+R EMPPHIF+I+D AY +MLQ+RE+QSIL TGESGAGKTENTK
Sbjct: 124 RFPIYTEQVALKYKGKRRGEMPPHIFSISDNAYHNMLQDRENQSILITGESGAGKTENTK 183
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVI Y A VA A++ + +++ + G LE Q++QANP+LEA+GN+KT +
Sbjct: 184 KVISYFAVVAAASKKEDDDSSKK-------------GTLEDQIVQANPVLEAYGNAKTTR 230
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
N+NSSRFGKFIRI+F +G I+GA+IE YLLEKSRV+ Q + ER++HIFYQ+L +K
Sbjct: 231 NNNSSRFGKFIRIHFGTTGKIAGADIEHYLLEKSRVVSQMKGERNYHIFYQLLSTYGSKY 290
Query: 907 KSEYLLEGVDNYRFLVNRG-ITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVL 1083
+ L++ +N+G +T+ VDD +E + ++GF DDE S+ + +++
Sbjct: 291 HDKLLVQTDPALYSFINQGELTIDGVDDSEEMKLCDEAFEVLGFNDDEKLSLFKCTTSIC 350
Query: 1084 LLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQ 1263
+G ++F Q + +QA +KV LLG+ +L +FL+P++KVG EFV K QN
Sbjct: 351 NMGEMKFKQRPREEQAEADGTAEAEKVAFLLGVNAKDLLTSFLKPKVKVGTEFVTKGQNL 410
Query: 1264 EQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQI 1443
Q +AV A+AK+ Y R+F WLV R+NK+LD T + FIG+LDIAGFEIF N FEQI
Sbjct: 411 NQVTYAVSALAKSLYNRMFGWLVARVNKTLD-TKVKRQFFIGVLDIAGFEIFTENGFEQI 469
Query: 1444 CINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDE 1623
CINYTNE+LQQ FN+ MF+LEQEEY+RE I+W FIDFG+DLQ IDLIEKPMG+L++L+E
Sbjct: 470 CINYTNERLQQFFNHHMFVLEQEEYKREKIQWTFIDFGMDLQACIDLIEKPMGILSILEE 529
Query: 1624 ECLFPKANDKSFVEKLQKTH-NKHPKFIVPDMRS----KSHFAVVHYAGRVDYSADQWLM 1788
EC+ PKA+D++F+ KL H K P F P ++HF + HYAG V Y+ WL
Sbjct: 530 ECIVPKASDQTFLSKLYDNHLGKSPNFTKPKPPKPGHVEAHFELHHYAGSVPYTITGWLE 589
Query: 1789 KNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLH 1968
KN DPLN++VV L+ +S DP V+ ++ + E G +++ G F TV+ +H
Sbjct: 590 KNKDPLNDSVVALLGDSKDPLVSNLFTPV---------VGEP--GKKTKGGSFLTVTYMH 638
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
+E L KLM L++TSP F+RCI+PN K+ G I+++LVL QL CNGVLEGIRICR+GFPN
Sbjct: 639 RESLNKLMKNLQSTSPSFIRCIVPNEFKQPGVIDAHLVLHQLHCNGVLEGIRICRKGFPN 698
Query: 2149 RVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAH 2328
R+ + EF+ RY IL P+VIP F+DG++ K++ A +D NLY+ G +KVFF+ G LAH
Sbjct: 699 RMIYSEFKQRYSILAPNVIPDGFVDGRQVTEKILEATQLDKNLYQCGNTKVFFKAGTLAH 758
Query: 2329 LEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRL 2508
LE+ RD KL +I FQA+ RG+L R+ Y N YL LRNW WWRL
Sbjct: 759 LEDLRDDKLNGIISLFQAEIRGYLMRKQYKKLQDQRVALTLMQRNIRKYLVLRNWPWWRL 818
Query: 2509 FTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQ 2688
+TKVKP+L + R ++E++ +EL KE K+E +E E++ V+ ++ + QLQ
Sbjct: 819 YTKVKPMLNIARQEEEMKKAAEELAKLKEEYEKLEKLKKELEEQNVTVLQQKNDLFLQLQ 878
Query: 2689 QESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXX 2868
E ++ A+ ++ +L + ++E + ++ +RL+ ++K + +
Sbjct: 879 TEQDSLADAEEKISKLVLQRGDMEQRIKELEERLADEEDQAANLTEVKKKMSAEIEELKK 938
Query: 2869 XXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLD 3048
+K D + L
Sbjct: 939 DVEDLESSLQKAEQEKQTKDNQIRTLQSEMAQQDEMIGKLNKDKKNLEEQNKRTQEALQA 998
Query: 3049 HEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGK 3228
E++ H K K +LE+ L E+E++L RE++ + ++E+ KRKL +L+ +++ + +
Sbjct: 999 EEDKVNHLNKLKAKLESTLDEMEENLAREQKIRGDVEKSKRKLEGDLKATQETVDDLERV 1058
Query: 3229 VEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKA 3408
+L QL +++ E+ ++++E V +Q++++++QT I EL ED+E ER AR+KA
Sbjct: 1059 KRDLEEQLRRKEAEIGGLSGKFEDEQGLVAQLQRKIKELQTRIQELEEDLEAERAARSKA 1118
Query: 3409 EMTRREVVAQLEKVKGDVLDKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEE 3585
E +R+++ ++LE+V D L++ D AT Q DL +++ E+ KR +E + E I
Sbjct: 1119 EKSRQQLESELEEVV-DRLEEQDGATAAQSDLTKKREAELMKLKRDLEDTRLQNEQAIAT 1177
Query: 3586 QKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKI 3765
+ K S + EL DQ++Q K +++ EK+++Q E D ++ + ++ + +K K
Sbjct: 1178 MRKKQSDAINELADQLDQANKAKAKAEKERSQFKAELDDAHNQVDSIMKAKLNSEKTVKA 1237
Query: 3766 HEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
E+ L E+ L E+ + RS E+ L R EE E + + +
Sbjct: 1238 LESQLQEVSVKLDEATRNLNEQASTKARSSQEVSELQRQLEEAESQLSQLNKIKQQLSAQ 1297
Query: 3946 XXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEA 4125
+R+K R L + ++L + EE + + L++++ + +
Sbjct: 1298 LEEARHSLEDESRMKAKLNGEVRNLTSDLDSLRETLEEEQSAKGDLQRQLQKLQGELQQL 1357
Query: 4126 RRK---AEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSME 4296
R + + ++++EEL++K + L+ + E ++ ++ ++K ++Q ELED ++
Sbjct: 1358 RSRGGGGGDVRSEEVEELKRKMNAKIPALESEAESAKSKCGQLEKTKARLQGELEDLMVD 1417
Query: 4297 LENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIM 4476
+E E++Q F +AE + + + + ++ R + T + L +++ +
Sbjct: 1418 VERANGLASQLERKQNNFNRTLAEWQKKYADSQAELENAQRDARGQSTEIFRLKAQLEEV 1477
Query: 4477 KEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNL 4656
E +E R ++L E+ D + G++VHE++K +R LE E +++ +EE E L
Sbjct: 1478 HEQMEGLRRENKNLSDEIHDLTEQLGEGGRSVHEIDKNRRRLEMEKEELQAALEEAESAL 1537
Query: 4657 QIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGA 4836
+ E R ++ ++ E DR ++ K+ E E R+ + + + LE E +GK+ A
Sbjct: 1538 EQEEAKVQRAQLEMSQIRQEIDRRLAEKEEEFEATRKNHQRAMESQQASLEAEGKGKAEA 1597
Query: 4837 VSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALL 5016
+ +KK+E I ELE L+ ANR + E E Q + E+ ++ ++D+
Sbjct: 1598 MRVKKKLEQDINELEVSLDGANRARAEQEENVKKFQQQVRELQSQLEDDQRQRDDLREQF 1657
Query: 5017 READRKFRAVEAEREQLREANEGLMQARK----QXXXXXXXXXXXRAKGGGISSEEKRRL 5184
+ A+R+ + E ++LR A + ++RK + + +++ +KR+L
Sbjct: 1658 QAAERRATVLAGELDELRIALDQAERSRKIAEAERAEASDRATEMSTQTASLAA-QKRKL 1716
Query: 5185 EAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSN 5364
EA +A + + A ++ +KA ++ ++ E+ Q E ++ LE
Sbjct: 1717 EADLAAMQADLEEAANEAKQADERAKKAMADSARVFEEIRQEQEHTQHVEKARKQLEIQV 1776
Query: 5365 RDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDT 5544
++ A++ + ESGA R M LE +V+ LE +L E + + R++++R+ +
Sbjct: 1777 KELMARLEDSESGAMKNGRKAMGKLEQRVRELETELAAEQRRHGETQKNLRKVDRRMKEI 1836
Query: 5545 TQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDAN 5724
+ Q E++K+++++ +EL+EK K + +RQ+ EAE+ + K+R +Q E +D +
Sbjct: 1837 SLQAEEDKKSHDRMQELVEKLQGKIKTYKRQVQEAEEIAAINLAKYRKIQHEIEDAEERA 1896
Query: 5725 EQLTREL 5745
+Q + L
Sbjct: 1897 DQAEQAL 1903
Score = 47.8 bits (112), Expect = 0.003
Identities = 41/149 (27%), Positives = 70/149 (46%), Gaps = 15/149 (10%)
Frame = +1
Query: 3028 LTTQLLDHEERA-KHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKL--------L 3180
L +L D E A K+G KA G+LE ++ ELE +L E++ E +++ RK+ L
Sbjct: 1779 LMARLEDSESGAMKNGRKAMGKLEQRVRELETELAAEQRRHGETQKNLRKVDRRMKEISL 1838
Query: 3181 AELEDSKDH-----LAEKM-GKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRD 3342
ED K H L EK+ GK++ Q+ + +E L +Y + +Q ++ D
Sbjct: 1839 QAEEDKKSHDRMQELVEKLQGKIKTYKRQVQEAEEIAAINLAKYRK-------IQHEIED 1891
Query: 3343 MQTTIDELREDMETERNARNKAEMTRREV 3429
+ D+ + ++ R + T R V
Sbjct: 1892 AEERADQAEQALQKLRAKNRSSVSTARGV 1920
>gi|127773|sp|P24733|MYS_AEQIR Myosin heavy chain, striated muscle
gi|102700|pir||A40997 myosin heavy chain, striated adductor muscle -
scallop (Aequipecten irradians)
gi|5612|emb|CAA39247.1| myosin heavy chain [Argopecten irradians]
Length = 1938
Score = 1191 bits (3081), Expect = 0.0
Identities = 671/1919 (34%), Positives = 1084/1919 (55%), Gaps = 18/1919 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
D QYL V R + T AA+ +K CWVPD+ EGF I+ DE+ V++V S
Sbjct: 9 DFQYLAVDRKKLMKEQT-AAFDGKKNCWVPDEKEGFASAEIQSSKGDEITVKIVADSSTR 67
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
T+ +DD+Q NPPKF+K+EDM+ +TYLNEASVL+NL+ RY S LIYTYSGLFC+ +NPY+
Sbjct: 68 TVKKDDIQSMNPPKFEKLEDMANMTYLNEASVLYNLRSRYTSGLIYTYSGLFCIAVNPYR 127
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
+LPIY++ +I +++GK++ E+PPH+F++AD AY++M+ +RE+QS L TGESGAGKTENTK
Sbjct: 128 RLPIYTDSVIAKYRGKRKTEIPPHLFSVADNAYQNMVTDRENQSCLITGESGAGKTENTK 187
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVI YLA VA A + K A+ ++ G LE Q++QANP+LEA+GN+KT +
Sbjct: 188 KVIMYLAKVACAVKKKDEEASDKKE-----------GSLEDQIIQANPVLEAYGNAKTTR 236
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
N+NSSRFGKFIRI+F +G I+GA+IE YLLEKSRV Q ER++HIFYQI + E
Sbjct: 237 NNNSSRFGKFIRIHFGPTGKIAGADIETYLLEKSRVTYQQSAERNYHIFYQICSN-AIPE 295
Query: 907 KSEYLLEGVDN--YRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAV 1080
++ +L D+ Y F+ +T+ N+DDV+EF + I+GF +E S+ + +++
Sbjct: 296 LNDVMLVTPDSGLYSFINQGCLTVDNIDDVEEFKLCDEAFDILGFTKEEKQSMFKCTASI 355
Query: 1081 LLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQN 1260
L +G ++F Q + +QA +KV L G+ +L KA L+P++KVG E V K QN
Sbjct: 356 LHMGEMKFKQRPREEQAESDGTAEAEKVAFLCGINAGDLLKALLKPKVKVGTEMVTKGQN 415
Query: 1261 QEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQ 1440
Q +V A+AK+ Y+R+F WLV R+NK+LD T + +IG+LDIAGFEIFD NSFEQ
Sbjct: 416 MNQVVNSVGALAKSLYDRMFNWLVRRVNKTLD-TKAKRNYYIGVLDIAGFEIFDFNSFEQ 474
Query: 1441 ICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLD 1620
+CINYTNE+LQQ FN+ MFILEQEEY++EGI W+FIDFG+DLQ IDLIEKPMG+L++L+
Sbjct: 475 LCINYTNERLQQFFNHHMFILEQEEYKKEGIAWEFIDFGMDLQMCIDLIEKPMGILSILE 534
Query: 1621 EECLFPKANDKSFVEKLQKTH-NKHPKFIVPDMRSK-----SHFAVVHYAGRVDYSADQW 1782
EEC+FPKA+DKSF +KL + H K+ F P ++ +HF + HYAG V YS W
Sbjct: 535 EECMFPKADDKSFQDKLYQNHMGKNRMFTKPGKPTRPNQGPAHFELHHYAGNVPYSITGW 594
Query: 1783 LMKNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGM---FRT 1953
L KN DP+NENVV L+ S +P VA ++K E E A G + +KG F+T
Sbjct: 595 LEKNKDPINENVVALLGASKEPLVAELFKAPE----------EPAGGGKKKKGKSSAFQT 644
Query: 1954 VSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICR 2133
+S +H+E L KLM L +T PHFVRCIIPN K+ G +++ LVL QL+CNGVLEGIRICR
Sbjct: 645 ISAVHRESLNKLMKNLYSTHPHFVRCIIPNELKQPGLVDAELVLHQLQCNGVLEGIRICR 704
Query: 2134 QGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRT 2313
+GFP+R+ + EF+ RY IL P+ IP+ F+DGK K++ L +D YR+G +KVFF+
Sbjct: 705 KGFPSRLIYSEFKQRYSILAPNAIPQGFVDGKTVSEKILAGLQMDPAEYRLGTTKVFFKA 764
Query: 2314 GVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNW 2493
GVL +LEE RD +L+ +I FQA RG+L R+ Y N +L LRNW
Sbjct: 765 GVLGNLEEMRDERLSKIISMFQAHIRGYLIRKAYKKLQDQRIGLSVIQRNIRKWLVLRNW 824
Query: 2494 QWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVI 2673
QWW+L++KVKPLL + R ++E++ + ++ KE L K E +E E++ ++ ++ +
Sbjct: 825 QWWKLYSKVKPLLSIARQEEEMKEQLKQMDKMKEDLAKTERIKKELEEQNVTLLEQKNDL 884
Query: 2674 QEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETV 2853
QLQ ++ + ++ +L + + E + ++ +RL ++K
Sbjct: 885 FLQLQTLEDSMGDQEERVEKLIMQKADFESQIKELEERLLDEEDAAADLEGIKKKMEADN 944
Query: 2854 RDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLT 3033
+ DK + D + +
Sbjct: 945 ANLKKDIGDLENTLQKAEQDKAHKDNQISTLQGEISQQDEHIGKLNKEKKALEEANKKTS 1004
Query: 3034 TQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLA 3213
L E++ H K K +LE L ELE +L RE++ + ++E+ KRK+ +L+ +++++
Sbjct: 1005 DSLQAEEDKCNHLNKLKAKLEQALDELEDNLEREKKVRGDVEKAKRKVEQDLKSTQENVE 1064
Query: 3214 EKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERN 3393
+ EL + +++ E+ ++ ++E V+ +Q++++++Q I+EL E++E ERN
Sbjct: 1065 DLERVKRELEENVRRKEAEISSLNSKLEDEQNLVSQLQRKIKELQARIEELEEELEAERN 1124
Query: 3394 ARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTME 3570
AR K E R E+ +LE++ G+ LD+ AT Q +L +++ E+ +R +E+ E
Sbjct: 1125 ARAKVEKQRAELNRELEEL-GERLDEAGGATSAQIELNKKREAELLKIRRDLEEASLQHE 1183
Query: 3571 GKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADID 3750
+I + K E+ DQ++Q +K +S+LEK + +E D+ ++ ++ +
Sbjct: 1184 AQISALRKKHQDAANEMADQVDQLQKVKSKLEKDKKDLKREMDDLESQMTHNMKNKGCSE 1243
Query: 3751 KKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLA 3930
K K E+ + ++ A L +S L Q R + E L R E+ EH + + + +
Sbjct: 1244 KVMKQFESQMSDLNARLEDSQRSINELQSQKSRLQAENSDLTRQLEDAEHRVSVLSKEKS 1303
Query: 3931 TAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQ 4110
TR + N R + + +A+ ++ EE + ++ +++++ A
Sbjct: 1304 QLSSQLEDARRSLEEETRARSKLQNEVRNMHADMDAIREQLEEEQESKSDVQRQLSKANN 1363
Query: 4111 GAGEARRKAE-ESVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELE 4281
+ R K E E N ++LE+ ++K L + ++ E + + ++K ++QQELE
Sbjct: 1364 EIQQWRSKFESEGANRTEELEDQKRKLLGKLSEAEQTTEAANAKCSALEKAKSRLQQELE 1423
Query: 4282 DSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLN 4461
D S+E++ AS EK+Q+ F+ AE + V + + +E R + +
Sbjct: 1424 DMSIEVDRANASVNQMEKKQRAFDKTTAEWQAKVNSLQSELENSQKESRGYSAELYRIKA 1483
Query: 4462 EVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE 4641
++ ++ + R ++L E+ D + G++ HEL+KA+R LE E +++ +EE
Sbjct: 1484 SIEEYQDSIGALRRENKNLADEIHDLTDQLSEGGRSTHELDKARRRLEMEKEELQAALEE 1543
Query: 4642 LEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKR 4821
E L+ E +R ++ +++E D+ I K+ E + RR + + ++ LE E +
Sbjct: 1544 AEGALEQEEAKVMRAQLEIATVRNEIDKRIQEKEEEFDNTRRNHQRALESMQASLEAEAK 1603
Query: 4822 GKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKED 5001
GK+ A+ +KK+E I ELE L+ +NR K E E Q EE ++ +++
Sbjct: 1604 GKADAMRIKKKLEQDINELEVALDASNRGKAEMEKTVKRYQQQIREMQTSIEEEQRQRDE 1663
Query: 5002 IAALLREADRKFRAVEAEREQLREANEGLMQARK-QXXXXXXXXXXXRAKGGGISS--EE 5172
A+R+ + E E+LR A E +ARK +SS +
Sbjct: 1664 ARESYNMAERRCTLMSGEVEELRAALEQAERARKASDNELADANDRVNELTSQVSSVQGQ 1723
Query: 5173 KRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSL 5352
KR+LE I + A ++ +KA ++ +L E+ + + E +++L
Sbjct: 1724 KRKLEGDINAMQTDLDEMHGELKGADERCKKAMADAARLADELRAEQDHSNQVEKVRKNL 1783
Query: 5353 ERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKR 5532
E ++++ ++ E E+ + + + LE++V LE +L+ E + + R+ ++R
Sbjct: 1784 ESQVKEFQIRLDEAEASSLKGGKKMIQKLESRVHELEAELDNEQRRHAETQKNMRKADRR 1843
Query: 5533 LNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
L + Q +++++ E+ +EL++K N K + +RQ++EAE+ + K+R Q E ++
Sbjct: 1844 LKELAFQADEDRKNQERLQELIDKLNAKIKTFKRQVEEAEEIAAINLAKYRKAQHELEE 1902
Score = 185 bits (469), Expect = 1e-44
Identities = 187/979 (19%), Positives = 400/979 (40%), Gaps = 43/979 (4%)
Frame = +1
Query: 2542 RTDDEIRAKDDE------LRATKERLLKMEHDFRENEKKL-DQVIVERAVIQEQLQQESE 2700
+T D ++A++D+ L+A E+ L D E EKK+ V + +++ L+ E
Sbjct: 1002 KTSDSLQAEEDKCNHLNKLKAKLEQALDELEDNLEREKKVRGDVEKAKRKVEQDLKSTQE 1061
Query: 2701 NSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXX 2880
N +L+ ++ L+ + E ++ + +L ++ + +
Sbjct: 1062 NVEDLERVKRELEENVRRKEAEISSLNSKLEDEQNLVSQLQRKIKELQARIEELEEELEA 1121
Query: 2881 XXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEER 3060
+ +++ A + L + +
Sbjct: 1122 ERNARAKVEKQRAELNRELEELGERLDEAGGATSAQIELNKKREAELLKIRRDLEEASLQ 1181
Query: 3061 AKHGVKA-KGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKM----- 3222
+ + A + + ++ +E+ +++ ++ KS+LE+ K+ L E++D + + M
Sbjct: 1182 HEAQISALRKKHQDAANEMADQVDQLQKVKSKLEKDKKDLKREMDDLESQMTHNMKNKGC 1241
Query: 3223 ---------GKVEELNNQL---MKRDEELQHQLTRYDEESANVT-----------LMQKQ 3333
++ +LN +L + ELQ Q +R E++++T ++ K+
Sbjct: 1242 SEKVMKQFESQMSDLNARLEDSQRSINELQSQKSRLQAENSDLTRQLEDAEHRVSVLSKE 1301
Query: 3334 MRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRK 3513
+ + +++ R +E E AR+K + R + A ++ ++ + ++ + + +Q +S+
Sbjct: 1302 KSQLSSQLEDARRSLEEETRARSKLQNEVRNMHADMDAIREQLEEEQESKSDVQRQLSKA 1361
Query: 3514 DEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQE 3693
+ E+ + E ++E+QK K ++ E E + S LEK +++ QE
Sbjct: 1362 NNEIQQWRSKFESEGANRTEELEDQKRKLLGKLSEAEQTTEAANAKCSALEKAKSRLQQE 1421
Query: 3694 RADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHL 3873
DM+ E+ AS ++KK++ + E QA + + + L + + SR L
Sbjct: 1422 LEDMSIEVDRANASVNQMEKKQRAFDKTTAEWQAKV---NSLQSELENSQKESRGYSAEL 1478
Query: 3874 NRVR---EEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALL 4044
R++ EE + + ++R R R+LE EK L
Sbjct: 1479 YRIKASIEEYQDSIGALRRENKNLADEIHDLTDQLSEGGRSTHELDKARRRLEMEKEELQ 1538
Query: 4045 DEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEEL---RKKNLRDVEHLQKQL 4215
EEAEG E ++ A+ R + ++ + ++ EE R+ + R +E +Q L
Sbjct: 1539 AALEEAEGALEQEEAKVMRAQLEIATVRNEIDKRIQEKEEEFDNTRRNHQRALESMQASL 1598
Query: 4216 EESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKAL 4395
E K ++ KKK++Q++ + + L+ + EK K+++ Q+ E + ++++
Sbjct: 1599 EAEAKGKADAMRIKKKLEQDINELEVALDASNRGKAEMEKTVKRYQQQIREMQTSIEEEQ 1658
Query: 4396 LDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVH 4575
RD + E R + EV+ ++ LE+++R R++ EL D+ ++ V
Sbjct: 1659 RQRDEARESYNMAERRCTLMSGEVEELRAALEQAERARKASDNELADANDRVNELTSQVS 1718
Query: 4576 ELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAE 4755
++ KR LE ++N M+ ++E+ L+ A D R + + + A ++ RA + + E
Sbjct: 1719 SVQGQKRKLEGDINAMQTDLDEMHGELKGA-DERCKKAMADAARLADELRAEQDHSNQVE 1777
Query: 4756 EKRRGLLKQIRDLENEL-ENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXX 4932
+ R+ L Q+++ + L E E G +K+E+++ ELE +L+ R E
Sbjct: 1778 KVRKNLESQVKEFQIRLDEAEASSLKGGKKMIQKLESRVHELEAELDNEQRRHAETQKN- 1836
Query: 4933 XXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXX 5112
+R+ADR+ + + + ++ R+ E L +
Sbjct: 1837 ---------------------------MRKADRRLKELAFQADEDRKNQERLQELID--- 1866
Query: 5113 XXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQIT 5292
+L AKI + + + K RKAQ +LE+
Sbjct: 1867 ----------------------KLNAKIKTFKRQVEEAEEIAAINLAKYRKAQHELEEAE 1904
Query: 5293 TDLSMERTLNQKTEAEKQS 5349
+ QK A+ +S
Sbjct: 1905 ERADTADSTLQKFRAKSRS 1923
Score = 180 bits (456), Expect = 4e-43
Identities = 189/941 (20%), Positives = 404/941 (42%), Gaps = 59/941 (6%)
Frame = +1
Query: 3100 QLHELEQDLNRERQYKSELEQHKRKLLAELED---SKDHLAEKMGKVEELNNQLMKRDEE 3270
Q+ ++++DL + + K ELE+ LL + D L + MG EE +L+ + +
Sbjct: 852 QMDKMKEDLAKTERIKKELEEQNVTLLEQKNDLFLQLQTLEDSMGDQEERVEKLIMQKAD 911
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ Q+ +E L+ ++ D ++ +++ ME + NA K ++ E L+K
Sbjct: 912 FESQIKELEER-----LLDEE--DAAADLEGIKKKMEAD-NANLKKDIGDLENT--LQKA 961
Query: 3451 KGDVLDKVDEATMLQDLMSRKDEEV---NATKRAIEQIQHTMEGKIEEQ----------K 3591
+ D K ++ + LQ +S++DE + N K+A+E+ ++ + K
Sbjct: 962 EQDKAHKDNQISTLQGEISQQDEHIGKLNKEKKALEEANKKTSDSLQAEEDKCNHLNKLK 1021
Query: 3592 AKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHE 3771
AK + ++EL D +E+ KK R +EK + + +Q+ + + L+ + ++++ + E
Sbjct: 1022 AKLEQALDELEDNLEREKKVRGDVEKAKRKVEQDLKSTQENVEDLERVKRELEENVRRKE 1081
Query: 3772 AHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXX 3951
A + + + L E ++ L+ QL+R EL R+ E EE A R
Sbjct: 1082 AEISSLNSKL----EDEQNLVSQLQRKIKELQA--RIEELEEELEAERNARAKVEKQRAE 1135
Query: 3952 XXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARR 4131
RL A + Q+E L++K EAE L+ RR
Sbjct: 1136 LNRELEELGERLDEAGGATSAQIE------LNKKREAELLKI----------------RR 1173
Query: 4132 KAEESVNQ---QLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
EE+ Q Q+ LRKK+ + Q+++ + K ++ + KK +++E++D ++
Sbjct: 1174 DLEEASLQHEAQISALRKKHQDAANEMADQVDQLQKVKSKLEKDKKDLKREMDDLESQMT 1233
Query: 4303 NVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKE 4482
+ + SEK K+FESQM++ + L D EL+ +++R+ + E +
Sbjct: 1234 HNMKNKGCSEKVMKQFESQMSD----LNARLEDSQRSINELQSQKSRLQA---ENSDLTR 1286
Query: 4483 HLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQM----EELED 4650
LE+++ L +E S +D +++ E +A+ L+ E+ +M M E+LE+
Sbjct: 1287 QLEDAEHRVSVLSKEKSQLSSQLEDARRSLEEETRARSKLQNEVRNMHADMDAIREQLEE 1346
Query: 4651 NLQIAEDARLRLEVTN---QALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKR 4821
+ D + +L N Q +S+ + +N+ E E+++R LL ++ + E E
Sbjct: 1347 EQESKSDVQRQLSKANNEIQQWRSKFESEGANRTEELEDQKRKLLGKLSEAEQTTEAANA 1406
Query: 4822 GKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKED 5001
S + +++ ++ ++ +++ AN + E+Q + + E+
Sbjct: 1407 KCSALEKAKSRLQQELEDMSIEVDRANASVNQMEKKQRAFDKTTAEWQAKVNSLQSELEN 1466
Query: 5002 IAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSE---E 5172
R + ++A E+ +++ L + K ++GG + E
Sbjct: 1467 SQKESRGYSAELYRIKASIEEYQDSIGALRRENKNLADEIHDLTDQLSEGGRSTHELDKA 1526
Query: 5173 KRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSL 5352
+RRLE + + + E K +AQ+++ + ++ ++ + +K E +
Sbjct: 1527 RRRLEMEKEELQAALEEAEGALEQEEAKVMRAQLEIATVRNEI--DKRIQEKEEEFDNTR 1584
Query: 5353 ERSNRDYKAKITELESGAQSRARAQMAA--LEAKVQYLEDQLNVEGQEKTAANRAARRLE 5526
R ++ LE+ A+ +A A LE + LE L+ + K + +R +
Sbjct: 1585 RNHQRALESMQASLEAEAKGKADAMRIKKKLEQDINELEVALDASNRGKAEMEKTVKRYQ 1644
Query: 5527 KRLNDTTQQFEDEKR----------------------------ANEQAKELLEKSNLKNR 5622
+++ + E+E+R A EQA+ + S+ +
Sbjct: 1645 QQIREMQTSIEEEQRQRDEARESYNMAERRCTLMSGEVEELRAALEQAERARKASDNELA 1704
Query: 5623 NLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
+ +++E ++S + + R ++ + + + +++ EL
Sbjct: 1705 DANDRVNELTSQVSSVQGQKRKLEGDINAMQTDLDEMHGEL 1745
Score = 163 bits (412), Expect = 5e-38
Identities = 157/856 (18%), Positives = 365/856 (42%), Gaps = 52/856 (6%)
Frame = +1
Query: 3310 NVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATM 3489
++ +++M++ +D+++ED+ + R K E+ + V L + K D+ ++
Sbjct: 838 SIARQEEEMKEQLKQMDKMKEDLA--KTERIKKELEEQNVT--LLEQKNDLFLQLQT--- 890
Query: 3490 LQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEK 3669
L+D M ++E V K+ QKA F Q++EL +++ + + LE
Sbjct: 891 LEDSMGDQEERVE---------------KLIMQKADFESQIKELEERLLDEEDAAADLEG 935
Query: 3670 QQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEH---------- 3819
+ + + + A++ ++I L+ + ++ + + + +Q +++ DEH
Sbjct: 936 IKKKMEADNANLKKDIGDLENTLQKAEQDKAHKDNQISTLQGEISQQDEHIGKLNKEKKA 995
Query: 3820 ----KRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL 3987
+ D L+ D+ +HLN+++ + E A ++ L
Sbjct: 996 LEEANKKTSDSLQAEEDKCNHLNKLKAKLEQALDELEDNLEREKKVR------------- 1042
Query: 3988 KIANINRA-RQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVN--QQ 4158
++ +A R++E + + + E+ E ++ LE+ + K E+ N Q
Sbjct: 1043 --GDVEKAKRKVEQDLKSTQENVEDLERVKRELEENVRRKEAEISSLNSKLEDEQNLVSQ 1100
Query: 4159 LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKR 4338
L+ K+ +E L+++LE A+ ++ + + ++ +ELE+ L+ + +
Sbjct: 1101 LQRKIKELQARIEELEEELEAERNARAKVEKQRAELNRELEELGERLDEAGGATSAQIEL 1160
Query: 4339 QKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLS-LLNEVDIMKEHLEESDRVRRS 4515
KK E+++ + R +++A L +A LR + + + ++VD +++ + ++ ++
Sbjct: 1161 NKKREAELLKIRRDLEEASLQHEAQISALRKKHQDAANEMADQVDQLQKVKSKLEKDKKD 1220
Query: 4516 LQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVT 4695
L++E+ D S KN EK + E++++D+ ++E+ + ++ + + RL+
Sbjct: 1221 LKREMDDLESQMTHNMKNKGCSEKVMKQFESQMSDLNARLEDSQRSINELQSQKSRLQAE 1280
Query: 4696 NQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGE 4875
N L + + A V ++EK + L Q+ D LE E R +S K++N++
Sbjct: 1281 NSDLTRQLEDAEHRVSVLSKEKSQ-LSSQLEDARRSLEEETRARS-------KLQNEVRN 1332
Query: 4876 LEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAE 5055
+ ++ + EE +++K D+
Sbjct: 1333 MHADMDAIRE---------------------QLEEEQESKSDV----------------- 1354
Query: 5056 REQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSE---EKRRLEAKIAQXXXXXXXX 5226
+ QL +AN + Q R + ++G + E +KR+L K+++
Sbjct: 1355 QRQLSKANNEIQQWRSKF----------ESEGANRTEELEDQKRKLLGKLSEAEQTTEAA 1404
Query: 5227 QSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES-- 5400
+ C + + Q +LE ++ ++ + E ++++ +++ +++AK+ L+S
Sbjct: 1405 NAKCSALEKAKSRLQQELEDMSIEVDRANASVNQMEKKQRAFDKTTAEWQAKVNSLQSEL 1464
Query: 5401 -GAQSRAR---AQMAALEAKVQY---------------------LEDQLNVEGQEKTAAN 5505
+Q +R A++ ++A ++ L DQL+ G+ +
Sbjct: 1465 ENSQKESRGYSAELYRIKASIEEYQDSIGALRRENKNLADEIHDLTDQLSEGGRSTHELD 1524
Query: 5506 RAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLD----EAEDEMSRER 5673
+A RRLE + E+ + A EQ + + ++ L+ +R ++D E E+E R
Sbjct: 1525 KARRRLEMEKEELQAALEEAEGALEQEEAKVMRAQLEIATVRNEIDKRIQEKEEEFDNTR 1584
Query: 5674 TKHRNVQREADDLLDA 5721
H+ L+A
Sbjct: 1585 RNHQRALESMQASLEA 1600
>gi|33468583|emb|CAE30366.1| SI:dZ204D19.2 (novel protein similar to
human non-muscle myosin, heavy polypeptide 10 (MYH10))
[Danio rerio]
Length = 1065
Score = 1188 bits (3073), Expect = 0.0
Identities = 608/1068 (56%), Positives = 775/1068 (71%), Gaps = 9/1068 (0%)
Frame = +1
Query: 325 TYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSIL 504
TYSGLFCVVINPYK LPIYSE++IE ++GKKRHEMPPHI+AI+++AYR MLQ+REDQSIL
Sbjct: 1 TYSGLFCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSIL 60
Query: 505 CTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV-QKPDVRNPIGELEHQLLQ 681
CTGESGAGKTENTKKVIQYLAHVA + + + NI + P GELE QLLQ
Sbjct: 61 CTGESGAGKTENTKKVIQYLAHVASSHKGRK-----DHNIPPESPKAVKLQGELERQLLQ 115
Query: 682 ANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERS 861
ANPILE+FGN+KTVKNDNSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+
Sbjct: 116 ANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQAKDERT 175
Query: 862 FHIFYQILRGCSAKEKSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFAD 1041
FH+FYQ+L G +S+ LLEG ++YRFL N I +P D F T+ +M IM F
Sbjct: 176 FHVFYQLLAGAGEHLRSDLLLEGFNSYRFLSNGNIPIPGQQDKDNFQETMEAMHIMSFNH 235
Query: 1042 DEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPR 1221
+EI S+++VVSAVL GN+ F +E+ +DQA + ++ QK+CHLLG+ V+E +A L PR
Sbjct: 236 EEILSMLKVVSAVLQFGNIVFKKERNTDQASMPENTAAQKLCHLLGMNVMEFTRAILSPR 295
Query: 1222 IKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDI 1401
IKVGR++V KAQ +EQA+FAVEA+AKA+YERLF+WLV RINK+LDRT RQGASFIGILDI
Sbjct: 296 IKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDI 355
Query: 1402 AGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTID 1581
AGFEIF +NSFEQ+CINYTNEKLQQLFN+TMFILEQEEYQREGIEW FIDFGLDLQP ID
Sbjct: 356 AGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWSFIDFGLDLQPCID 415
Query: 1582 LIEKPM---GVLALLDEECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHY 1749
LIE+P GVLALLDEEC FPKA DK+FV+KL + H KF P ++ K+ F ++HY
Sbjct: 416 LIERPANPPGVLALLDEECWFPKATDKTFVDKLVQEQGTHGKFQKPRQLKDKADFCIIHY 475
Query: 1750 AGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAFG 1923
AGRVDY AD+WLMKNMDPLN+NV L+ STD FVA +WKD + G+ A MNETAFG
Sbjct: 476 AGRVDYKADEWLMKNMDPLNDNVATLLHQSTDKFVAELWKDVDRIVGLDQVAGMNETAFG 535
Query: 1924 --MRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLR 2097
+++KGMFRTV QL+KE LTKLM TLRNT+P+FVRCIIPNHEK++GK+ +LVL+QLR
Sbjct: 536 AAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLEPHLVLDQLR 595
Query: 2098 CNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNL 2277
CNGVLEGIRICRQGFPNR+ FQEFR RYEILTP+ IPK F+DGK++ +MI AL++D NL
Sbjct: 596 CNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNL 655
Query: 2278 YRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXX 2457
YRIGQSK+FFRTGVLAHLEEERDLK+T +I+ FQ+ CRG+L+R+ +
Sbjct: 656 YRIGQSKIFFRTGVLAHLEEERDLKITDIIIYFQSVCRGYLARKAFAKKQQQLSALKVLQ 715
Query: 2458 XNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEK 2637
N AYLKLR+WQWWRLFTKVKPLLQVTR ++E++AKD+EL KER +K+E++ E E+
Sbjct: 716 RNCAAYLKLRHWQWWRLFTKVKPLLQVTRQEEEMQAKDEELIKVKERQVKVENELVEMER 775
Query: 2638 KLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXX 2817
K Q++ E+ ++ EQLQ E+E AE +++R RL + QELE I++D+ R+
Sbjct: 776 KHQQLLEEKNILAEQLQAETELFAEAEEMRARLVAKKQELEEILHDLESRVEEEEERNQS 835
Query: 2818 XXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXX 2997
++K ++D +K + +D
Sbjct: 836 LQNEKKKMQSHIQDLEEQLDEEEAARQKLQLEKVTAEAKIKKMEEDILLLEDQNSKFLKE 895
Query: 2998 XXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKL 3177
+T+QL + EE+AK+ K K + E + +LE+ L +E + + ELE+ KRKL
Sbjct: 896 KKLLEDRVGEMTSQLAEEEEKAKNLGKVKNKQEMMMVDLEERLKKEEKTRQELEKAKRKL 955
Query: 3178 LAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTI 3357
AE D +D +AE +++EL QL K++EELQ L R DEE A KQ+R++Q +
Sbjct: 956 DAETTDLQDQIAELQAQIDELKIQLAKKEEELQAVLARGDEEVAQKNNALKQLRELQAQL 1015
Query: 3358 DELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDL 3501
EL+ED+E+E+ ARNKAE +R++ +LE +K ++ D +D Q+L
Sbjct: 1016 AELQEDLESEKAARNKAEKLKRDLSEELEALKTELEDTLDTTAAQQEL 1063
Score = 93.2 bits (230), Expect = 7e-17
Identities = 85/303 (28%), Positives = 149/303 (49%), Gaps = 11/303 (3%)
Frame = +1
Query: 3028 LTTQLLDHEERAKHGVKAKGR---LENQLHELE---QDLNRERQYKSELEQHKRKLLAEL 3189
+T Q + + + + +K K R +EN+L E+E Q L E+ +E Q + +L AE
Sbjct: 742 VTRQEEEMQAKDEELIKVKERQVKVENELVEMERKHQQLLEEKNILAEQLQAETELFAEA 801
Query: 3190 EDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELR 3369
E+ + L K ++EE+ + L R EE EE N +L Q + + MQ+ I +L
Sbjct: 802 EEMRARLVAKKQELEEILHDLESRVEE---------EEERNQSL-QNEKKKMQSHIQDLE 851
Query: 3370 EDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDE-ATMLQDLMSRKDEEVNATKRAI 3546
E ++ E AR K ++ + A+++K++ D+L D+ + L++ +D T +
Sbjct: 852 EQLDEEEAARQKLQLEKVTAEAKIKKMEEDILLLEDQNSKFLKEKKLLEDRVGEMTSQLA 911
Query: 3547 EQIQHTME-GKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIAL 3723
E+ + GK+ K K + +L +++++ +K R +LEK + + D E D+ +IA
Sbjct: 912 EEEEKAKNLGKV---KNKQEMMMVDLEERLKKEEKTRQELEKAKRKLDAETTDLQDQIAE 968
Query: 3724 LQASRADIDKKRKIHEAHLMEIQANLAESDE---HKRTLIDQLERSRDELDHLNRVREEE 3894
LQ A ID+ + E+QA LA DE K + QL + +L L E E
Sbjct: 969 LQ---AQIDELKIQLAKKEEELQAVLARGDEEVAQKNNALKQLRELQAQLAELQEDLESE 1025
Query: 3895 EHA 3903
+ A
Sbjct: 1026 KAA 1028
Score = 88.2 bits (217), Expect = 2e-15
Identities = 79/307 (25%), Positives = 153/307 (49%), Gaps = 13/307 (4%)
Frame = +1
Query: 4012 RQLEDEKNALLDEKE-------EAEGLRAHL---EKEIHAARQGAGEARRKAEESVNQQL 4161
+QL +EKN L ++ + EAE +RA L ++E+ E+R + EE NQ L
Sbjct: 778 QQLLEEKNILAEQLQAETELFAEAEEMRARLVAKKQELEEILHDL-ESRVEEEEERNQSL 836
Query: 4162 EELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQ 4341
+ +KK ++ L++QL+E E A++++ +K+ E + ME + + ++S+ +
Sbjct: 837 QNEKKKMQSHIQDLEEQLDEEEAARQKL--QLEKVTAEAKIKKMEEDILLLEDQNSKFLK 894
Query: 4342 KKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSL---LNEVDIMKEHLEESDRVRR 4512
+K ++ E+RV M+ +L + E + +L N+ ++M LEE +
Sbjct: 895 EK---KLLEDRVG---------EMTSQLAEEEEKAKNLGKVKNKQEMMMVDLEERLKKEE 942
Query: 4513 SLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEV 4692
+QEL EKAKR L+AE D++ Q+ EL+ + + + E
Sbjct: 943 KTRQEL-----------------EKAKRKLDAETTDLQDQIAELQAQIDELKIQLAKKEE 985
Query: 4693 TNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIG 4872
QA+ + D ++ K+ A ++ R L Q+ +L+ +LE+EK ++ A ++ + ++
Sbjct: 986 ELQAVLARGDEEVAQKN-NALKQLRELQAQLAELQEDLESEKAARNKAEKLKRDLSEELE 1044
Query: 4873 ELEQQLE 4893
L+ +LE
Sbjct: 1045 ALKTELE 1051
Score = 81.6 bits (200), Expect = 2e-13
Identities = 75/358 (20%), Positives = 162/358 (44%), Gaps = 5/358 (1%)
Frame = +1
Query: 3247 QLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRRE 3426
Q+ +++EE+Q + DEE V Q ++ + ++ + + E+N + E
Sbjct: 741 QVTRQEEEMQAK----DEELIKVKERQVKVENELVEMERKHQQLLEEKNILAEQLQAETE 796
Query: 3427 VVAQLEKVKGDVLDKVDEAT-MLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFS 3603
+ A+ E+++ ++ K E +L DL SR +EE + ++ +K K
Sbjct: 797 LFAEAEEMRARLVAKKQELEEILHDLESRVEEEEERNQ------------SLQNEKKKMQ 844
Query: 3604 RQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLM 3783
+++L +Q+++ + R +L+ ++ A+ + M ++I LL+ + K++K+ E +
Sbjct: 845 SHIQDLEEQLDEEEAARQKLQLEKVTAEAKIKKMEEDILLLEDQNSKFLKEKKLLEDRVG 904
Query: 3784 EIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXX 3963
E+ + LAE +E + +L +V+ ++E +++ RL
Sbjct: 905 EMTSQLAEEEEKAK--------------NLGKVKNKQEMMMVDLEERLKKEEK------- 943
Query: 3964 XXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEE 4143
TR ++ R +L+ E L D+ E + L+ ++ + + +E
Sbjct: 944 -----TRQELEKAKR--KLDAETTDLQDQIAELQAQIDELKIQLAKKEEELQAVLARGDE 996
Query: 4144 SVNQQLEELRKKNLRDVE----HLQKQLEESEVAKERILQSKKKIQQELEDSSMELEN 4305
V Q+ L K LR+++ LQ+ LE + A+ + + K+ + +ELE ELE+
Sbjct: 997 EVAQKNNAL--KQLRELQAQLAELQEDLESEKAARNKAEKLKRDLSEELEALKTELED 1052
Score = 54.3 bits (129), Expect = 4e-05
Identities = 75/392 (19%), Positives = 167/392 (42%), Gaps = 46/392 (11%)
Frame = +1
Query: 4066 GLRAHLEKE---------IHAARQGAGEARRKAEESVNQQLEELR--KKN---------- 4182
G+ AHLE+E I+ G RKA QQL L+ ++N
Sbjct: 668 GVLAHLEEERDLKITDIIIYFQSVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHW 727
Query: 4183 --------LRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKR 4338
++ + + +Q EE + E +++ K++ Q ++E+ +E+E K
Sbjct: 728 QWWRLFTKVKPLLQVTRQEEEMQAKDEELIKVKER-QVKVENELVEMER---------KH 777
Query: 4339 QKKFESQ--MAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRV-- 4506
Q+ E + +AE+ A + + + M L ++ + +L++++ E EE ++
Sbjct: 778 QQLLEEKNILAEQLQAETELFAEAEEMRARLVAKKQELEEILHDLESRVEEEEERNQSLQ 837
Query: 4507 --RRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARL 4680
++ +Q +Q D + + E E A++ L+ E +++++E+++ + ED
Sbjct: 838 NEKKKMQSHIQ-------DLEEQLDEEEAARQKLQLEKVTAEAKIKKMEEDILLLEDQNS 890
Query: 4681 RLEVTNQALKSESDRAISNKDVEAEEKRRGLLK-------QIRDLENELENEKRGKSGAV 4839
+ + + L + ++++ E EEK + L K + DLE L+ E++ +
Sbjct: 891 KF-LKEKKLLEDRVGEMTSQLAEEEEKAKNLGKVKNKQEMMMVDLEERLKKEEKTRQELE 949
Query: 4840 SHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEAR----QAKEDIA 5007
++K++ + +L+ Q+ E Q + +E + + +E++
Sbjct: 950 KAKRKLDAETTDLQDQI---------------------AELQAQIDELKIQLAKKEEELQ 988
Query: 5008 ALLREADRKFRAVEAEREQLREANEGLMQARK 5103
A+L D + +QLRE L + ++
Sbjct: 989 AVLARGDEEVAQKNNALKQLRELQAQLAELQE 1020
Score = 37.4 bits (85), Expect = 4.4
Identities = 39/155 (25%), Positives = 70/155 (45%), Gaps = 16/155 (10%)
Frame = +1
Query: 5326 KTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQ-----E 5490
+ E E Q+ + K + ++E+ R LE K L +QL E + E
Sbjct: 744 RQEEEMQAKDEELIKVKERQVKVENELVEMERKHQQLLEEK-NILAEQLQAETELFAEAE 802
Query: 5491 KTAANRAARR--LEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMS 5664
+ A A++ LE+ L+D + E+E+ N+ + +K ++L QLD E+E +
Sbjct: 803 EMRARLVAKKQELEEILHDLESRVEEEEERNQSLQNEKKKMQSHIQDLEEQLD--EEEAA 860
Query: 5665 RERTKHRNVQREA------DDLL---DANEQLTRE 5742
R++ + V EA +D+L D N + +E
Sbjct: 861 RQKLQLEKVTAEAKIKKMEEDILLLEDQNSKFLKE 895
>gi|497653|gb|AAC46490.1| myosin heavy chain
gi|1093399|prf||2103335A myosin:SUBUNIT=heavy chain
Length = 1951
Score = 1182 bits (3059), Expect = 0.0
Identities = 670/1920 (34%), Positives = 1084/1920 (55%), Gaps = 19/1920 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
D QYL V R + T AA+ +K CWVPD+ EGF I+ DE+ V++V S
Sbjct: 9 DFQYLAVDRKKLMKEQT-AAFDGKKNCWVPDEKEGFASAEIQSSKGDEITVKIVADSSTR 67
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
T+ +DD+Q NPPKF+K+EDM+ +TYLNEASVL+NL+ RY S LIYTYSGLFC+ +NPY+
Sbjct: 68 TVKKDDIQSMNPPKFEKLEDMANMTYLNEASVLYNLRSRYTSGLIYTYSGLFCIAVNPYR 127
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
+LPIY++ +I +++GK++ E+PPH+F++AD AY++M+ +RE+QS L TGESGAGKTE+TK
Sbjct: 128 RLPIYTDSVIAKYRGKRKTEIPPHLFSVADNAYQNMVTDRENQSCLITGESGAGKTESTK 187
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNP-IGELEHQLLQANPILEAFGNSKTV 723
KVI Y A VA N Q+ ++P + LE Q+++ANP+LEAFGN+KTV
Sbjct: 188 KVIMYFARVAA-------NLYKQKQ--EEPTTTHARASNLEDQIIEANPVLEAFGNAKTV 238
Query: 724 KNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAK 903
+N+NSSRFGKFIRI+F +G I+GA+IE YLLEKSRV Q ER++HIFYQI +
Sbjct: 239 RNNNSSRFGKFIRIHFGPTGKIAGADIETYLLEKSRVTYQQSAERNYHIFYQICSN-AIP 297
Query: 904 EKSEYLLEGVDN--YRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSA 1077
E ++ +L D+ Y F+ +T+ N+DDV+EF + I+GF +E S+ + ++
Sbjct: 298 ELNDVMLVTPDSGLYSFINQGCLTVDNIDDVEEFKLCDEAFDILGFTKEEKQSMFKCTAS 357
Query: 1078 VLLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQ 1257
+L +G ++F Q + +QA +KV L G+ +L KA L+P++KVG E V K Q
Sbjct: 358 ILHMGEMKFKQRPREEQAESDGTAEAEKVAFLCGINAGDLLKALLKPKVKVGTEMVTKGQ 417
Query: 1258 NQEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFE 1437
N Q +V A+AK+ Y+R+F WLV R+NK+LD T + +IG+LDIAGFEIFD NSFE
Sbjct: 418 NMNQVVNSVGALAKSLYDRMFNWLVRRVNKTLD-TKAKRNYYIGVLDIAGFEIFDFNSFE 476
Query: 1438 QICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALL 1617
Q+CINYTNE+LQQ FN+ MFILEQEEY++EGI W+FIDFG+DLQ IDLIEKPMG+L++L
Sbjct: 477 QLCINYTNERLQQFFNHHMFILEQEEYKKEGIAWEFIDFGMDLQMCIDLIEKPMGILSIL 536
Query: 1618 DEECLFPKANDKSFVEKLQKTH-NKHPKFIVPDMRSK-----SHFAVVHYAGRVDYSADQ 1779
+EEC+FPKA+DKSF +KL + H K+ F P ++ +HF + HYAG V YS
Sbjct: 537 EEECMFPKADDKSFQDKLYQNHMGKNRMFTKPGKPTRPNQGPAHFELHHYAGNVPYSITG 596
Query: 1780 WLMKNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGM---FR 1950
WL KN DP+NENVV L+ S +P VA ++K E E A G + +KG F+
Sbjct: 597 WLEKNKDPINENVVALLGASKEPLVAELFKAPE----------EPAGGGKKKKGKSSAFQ 646
Query: 1951 TVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRIC 2130
T+S +H+E L KLM L +T PHFVRCIIPN K+ G +++ LVL QL+CNGVLEGIRIC
Sbjct: 647 TISAVHRESLNKLMKNLYSTHPHFVRCIIPNELKQPGLVDAELVLHQLQCNGVLEGIRIC 706
Query: 2131 RQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFR 2310
R+GFP+R+ + EF+ RY IL P+ IP+ F+DGK K++ L +D YR+G +KVFF+
Sbjct: 707 RKGFPSRLIYSEFKQRYSILAPNAIPQGFVDGKTVSEKILAGLQMDPAEYRLGTTKVFFK 766
Query: 2311 TGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRN 2490
GVL +LEE RD +L+ +I FQA RG+L R+ Y N +L LRN
Sbjct: 767 AGVLGNLEEMRDERLSKIISMFQAHIRGYLIRKAYKKLQDQRIGLSVIQRNIRKWLVLRN 826
Query: 2491 WQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAV 2670
WQWW+L++KVKPLL + R ++E++ + ++ KE L K E +E E++ ++ ++
Sbjct: 827 WQWWKLYSKVKPLLSIARQEEEMKEQLKQMDKMKEDLAKTERIKKELEEQNVTLLEQKND 886
Query: 2671 IQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMET 2850
+ QLQ ++ + ++ +L + + E + ++ +RL ++K
Sbjct: 887 LFLQLQTLEDSMGDQEERVEKLIMQKADFESQIKELEERLLDEEDAAADLEGIKKKMEAD 946
Query: 2851 VRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGL 3030
+ DK + D +
Sbjct: 947 NANLKKDIGDLENTLQKAEQDKAHKDNQISTLQGEISQQDEHIGKLNKEKKALEEANKKT 1006
Query: 3031 TTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL 3210
+ L E++ H K K +LE L ELE +L RE++ + ++E+ KRK+ +L+ +++++
Sbjct: 1007 SDSLQAEEDKCNHLNKLKAKLEQALDELEDNLEREKKVRGDVEKAKRKVEQDLKSTQENV 1066
Query: 3211 AEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETER 3390
+ EL + +++ E+ ++ ++E V+ +Q++++++Q I+EL E++E ER
Sbjct: 1067 EDLERVKRELEENVRRKEAEISSLNSKLEDEQNLVSQLQRKIKELQARIEELEEELEAER 1126
Query: 3391 NARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTM 3567
NAR K E R E+ +LE++ G+ LD+ AT Q +L +++ E+ +R +E+
Sbjct: 1127 NARAKVEKQRAELNRELEEL-GERLDEAGGATSAQIELNKKREAELLKIRRDLEEASLQH 1185
Query: 3568 EGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADI 3747
E +I + K E+ DQ++Q +K +S+ EK++ Q E D+ +I + ++
Sbjct: 1186 EAQISALRKKHQDAANEMADQVDQLQKVKSKSEKEKQQLRSEVEDLQAQIQHISKNKGCS 1245
Query: 3748 DKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRL 3927
+K K E+ + ++ A L +S L Q R + E L R E+ EH + + +
Sbjct: 1246 EKVMKQFESQMSDLNARLEDSQRSINELQSQKSRLQAENSDLTRQLEDAEHRVSVLSKEK 1305
Query: 3928 ATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAAR 4107
+ TR + N R + + +A+ ++ EE + ++ +++++ A
Sbjct: 1306 SQLSSQLEDARRSLEEETRARSKLQNEVRNMHADMDAIREQLEEEQESKSDVQRQLSKAN 1365
Query: 4108 QGAGEARRKAE-ESVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
+ R K E E N ++LE+ ++K L + ++ E + + ++K ++QQEL
Sbjct: 1366 NEIQQWRSKFESEGANRTEELEDQKRKLLGKLSEAEQTTEAANAKCSALEKAKSRLQQEL 1425
Query: 4279 EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLL 4458
ED S+E++ AS EK+Q+ F+ AE + V + + +E R + +
Sbjct: 1426 EDMSIEVDRANASVNQMEKKQRAFDKTTAEWQAKVNSLQSELENSQKESRGYSAELYRIK 1485
Query: 4459 NEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQME 4638
++ ++ + R ++L E+ D + G++ HEL+KA+R LE E +++ +E
Sbjct: 1486 ASIEEYQDSIGALRRENKNLADEIHDLTDQLSEGGRSTHELDKARRRLEMEKEELQAALE 1545
Query: 4639 ELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEK 4818
E E L+ E +R ++ +++E D+ I K+ E + RR + + ++ LE E
Sbjct: 1546 EAEGALEQEEAKVMRAQLEIATVRNEIDKRIQEKEEEFDNTRRNHQRALESMQASLEAEA 1605
Query: 4819 RGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKE 4998
+GK+ A+ +KK+E I ELE L+ +NR K E E Q EE ++ ++
Sbjct: 1606 KGKADAMRIKKKLEQDINELEVALDASNRGKAEMEKTVKRYQQQIREMQTSIEEEQRQRD 1665
Query: 4999 DIAALLREADRKFRAVEAEREQLREANEGLMQARK-QXXXXXXXXXXXRAKGGGISS--E 5169
+ A+R+ + E E+LR A E +ARK +SS
Sbjct: 1666 EARESYNMAERRCTLMSGEVEELRAALEQAERARKASDNELADANDRVNELTSQVSSVQG 1725
Query: 5170 EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQS 5349
+KR+LE I + A ++ +KA ++ +L E+ + + E +++
Sbjct: 1726 QKRKLEGDINAMQTDLDEMHGELKGADERCKKAMADAARLADELRAEQDHSNQVEKVRKN 1785
Query: 5350 LERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEK 5529
LE ++++ ++ E E+ + + + LE++V LE +L+ E + + R+ ++
Sbjct: 1786 LESQVKEFQIRLDEAEASSLKGGKKMIQKLESRVHELEAELDNEQRRHAETQKNMRKADR 1845
Query: 5530 RLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
RL + Q +++++ E+ +EL++K N K + +RQ++EAE+ + K+R Q E ++
Sbjct: 1846 RLKELAFQADEDRKNQERLQELIDKLNAKIKTFKRQVEEAEEIAAINLAKYRKAQHELEE 1905
Score = 184 bits (468), Expect = 2e-44
Identities = 188/979 (19%), Positives = 404/979 (41%), Gaps = 43/979 (4%)
Frame = +1
Query: 2542 RTDDEIRAKDDE------LRATKERLLKMEHDFRENEKKL-DQVIVERAVIQEQLQQESE 2700
+T D ++A++D+ L+A E+ L D E EKK+ V + +++ L+ E
Sbjct: 1005 KTSDSLQAEEDKCNHLNKLKAKLEQALDELEDNLEREKKVRGDVEKAKRKVEQDLKSTQE 1064
Query: 2701 NSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXX 2880
N +L+ ++ L+ + E ++ + +L ++ + +
Sbjct: 1065 NVEDLERVKRELEENVRRKEAEISSLNSKLEDEQNLVSQLQRKIKELQARIEELEEELEA 1124
Query: 2881 XXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEER 3060
+ +++ A + L + +
Sbjct: 1125 ERNARAKVEKQRAELNRELEELGERLDEAGGATSAQIELNKKREAELLKIRRDLEEASLQ 1184
Query: 3061 AKHGVKA-KGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSK---DHLAEKMG- 3225
+ + A + + ++ +E+ +++ ++ KS+ E+ K++L +E+ED + H+++ G
Sbjct: 1185 HEAQISALRKKHQDAANEMADQVDQLQKVKSKSEKEKQQLRSEVEDLQAQIQHISKNKGC 1244
Query: 3226 ----------KVEELNNQL---MKRDEELQHQLTRYDEESANVT-----------LMQKQ 3333
++ +LN +L + ELQ Q +R E++++T ++ K+
Sbjct: 1245 SEKVMKQFESQMSDLNARLEDSQRSINELQSQKSRLQAENSDLTRQLEDAEHRVSVLSKE 1304
Query: 3334 MRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRK 3513
+ + +++ R +E E AR+K + R + A ++ ++ + ++ + + +Q +S+
Sbjct: 1305 KSQLSSQLEDARRSLEEETRARSKLQNEVRNMHADMDAIREQLEEEQESKSDVQRQLSKA 1364
Query: 3514 DEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQE 3693
+ E+ + E ++E+QK K ++ E E + S LEK +++ QE
Sbjct: 1365 NNEIQQWRSKFESEGANRTEELEDQKRKLLGKLSEAEQTTEAANAKCSALEKAKSRLQQE 1424
Query: 3694 RADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHL 3873
DM+ E+ AS ++KK++ + E QA + + + L + + SR L
Sbjct: 1425 LEDMSIEVDRANASVNQMEKKQRAFDKTTAEWQAKV---NSLQSELENSQKESRGYSAEL 1481
Query: 3874 NRVR---EEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALL 4044
R++ EE + + ++R R R+LE EK L
Sbjct: 1482 YRIKASIEEYQDSIGALRRENKNLADEIHDLTDQLSEGGRSTHELDKARRRLEMEKEELQ 1541
Query: 4045 DEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEEL---RKKNLRDVEHLQKQL 4215
EEAEG E ++ A+ R + ++ + ++ EE R+ + R +E +Q L
Sbjct: 1542 AALEEAEGALEQEEAKVMRAQLEIATVRNEIDKRIQEKEEEFDNTRRNHQRALESMQASL 1601
Query: 4216 EESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKAL 4395
E K ++ KKK++Q++ + + L+ + EK K+++ Q+ E + ++++
Sbjct: 1602 EAEAKGKADAMRIKKKLEQDINELEVALDASNRGKAEMEKTVKRYQQQIREMQTSIEEEQ 1661
Query: 4396 LDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVH 4575
RD + E R + EV+ ++ LE+++R R++ EL D+ ++ V
Sbjct: 1662 RQRDEARESYNMAERRCTLMSGEVEELRAALEQAERARKASDNELADANDRVNELTSQVS 1721
Query: 4576 ELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAE 4755
++ KR LE ++N M+ ++E+ L+ A D R + + + A ++ RA + + E
Sbjct: 1722 SVQGQKRKLEGDINAMQTDLDEMHGELKGA-DERCKKAMADAARLADELRAEQDHSNQVE 1780
Query: 4756 EKRRGLLKQIRDLENEL-ENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXX 4932
+ R+ L Q+++ + L E E G +K+E+++ ELE +L+ R E
Sbjct: 1781 KVRKNLESQVKEFQIRLDEAEASSLKGGKKMIQKLESRVHELEAELDNEQRRHAETQKN- 1839
Query: 4933 XXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXX 5112
+R+ADR+ + + + ++ R+ E L +
Sbjct: 1840 ---------------------------MRKADRRLKELAFQADEDRKNQERLQELID--- 1869
Query: 5113 XXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQIT 5292
+L AKI + + + K RKAQ +LE+
Sbjct: 1870 ----------------------KLNAKIKTFKRQVEEAEEIAAINLAKYRKAQHELEEAE 1907
Query: 5293 TDLSMERTLNQKTEAEKQS 5349
+ QK A+ +S
Sbjct: 1908 ERADTADSTLQKFRAKSRS 1926
Score = 181 bits (460), Expect = 1e-43
Identities = 189/941 (20%), Positives = 405/941 (42%), Gaps = 59/941 (6%)
Frame = +1
Query: 3100 QLHELEQDLNRERQYKSELEQHKRKLLAELED---SKDHLAEKMGKVEELNNQLMKRDEE 3270
Q+ ++++DL + + K ELE+ LL + D L + MG EE +L+ + +
Sbjct: 855 QMDKMKEDLAKTERIKKELEEQNVTLLEQKNDLFLQLQTLEDSMGDQEERVEKLIMQKAD 914
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ Q+ +E L+ ++ D ++ +++ ME + NA K ++ E L+K
Sbjct: 915 FESQIKELEER-----LLDEE--DAAADLEGIKKKMEAD-NANLKKDIGDLENT--LQKA 964
Query: 3451 KGDVLDKVDEATMLQDLMSRKDEEV---NATKRAIEQIQHTMEGKIEEQ----------K 3591
+ D K ++ + LQ +S++DE + N K+A+E+ ++ + K
Sbjct: 965 EQDKAHKDNQISTLQGEISQQDEHIGKLNKEKKALEEANKKTSDSLQAEEDKCNHLNKLK 1024
Query: 3592 AKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHE 3771
AK + ++EL D +E+ KK R +EK + + +Q+ + + L+ + ++++ + E
Sbjct: 1025 AKLEQALDELEDNLEREKKVRGDVEKAKRKVEQDLKSTQENVEDLERVKRELEENVRRKE 1084
Query: 3772 AHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXX 3951
A + + + L E ++ L+ QL+R EL R+ E EE A R
Sbjct: 1085 AEISSLNSKL----EDEQNLVSQLQRKIKELQA--RIEELEEELEAERNARAKVEKQRAE 1138
Query: 3952 XXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARR 4131
RL A + Q+E L++K EAE L+ RR
Sbjct: 1139 LNRELEELGERLDEAGGATSAQIE------LNKKREAELLKI----------------RR 1176
Query: 4132 KAEESVNQ---QLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
EE+ Q Q+ LRKK+ + Q+++ + K + + K++++ E+ED +++
Sbjct: 1177 DLEEASLQHEAQISALRKKHQDAANEMADQVDQLQKVKSKSEKEKQQLRSEVEDLQAQIQ 1236
Query: 4303 NVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKE 4482
++ + SEK K+FESQM++ + L D EL+ +++R+ + E +
Sbjct: 1237 HISKNKGCSEKVMKQFESQMSD----LNARLEDSQRSINELQSQKSRLQA---ENSDLTR 1289
Query: 4483 HLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQM----EELED 4650
LE+++ L +E S +D +++ E +A+ L+ E+ +M M E+LE+
Sbjct: 1290 QLEDAEHRVSVLSKEKSQLSSQLEDARRSLEEETRARSKLQNEVRNMHADMDAIREQLEE 1349
Query: 4651 NLQIAEDARLRLEVTN---QALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKR 4821
+ D + +L N Q +S+ + +N+ E E+++R LL ++ + E E
Sbjct: 1350 EQESKSDVQRQLSKANNEIQQWRSKFESEGANRTEELEDQKRKLLGKLSEAEQTTEAANA 1409
Query: 4822 GKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKED 5001
S + +++ ++ ++ +++ AN + E+Q + + E+
Sbjct: 1410 KCSALEKAKSRLQQELEDMSIEVDRANASVNQMEKKQRAFDKTTAEWQAKVNSLQSELEN 1469
Query: 5002 IAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSE---E 5172
R + ++A E+ +++ L + K ++GG + E
Sbjct: 1470 SQKESRGYSAELYRIKASIEEYQDSIGALRRENKNLADEIHDLTDQLSEGGRSTHELDKA 1529
Query: 5173 KRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSL 5352
+RRLE + + + E K +AQ+++ + ++ ++ + +K E +
Sbjct: 1530 RRRLEMEKEELQAALEEAEGALEQEEAKVMRAQLEIATVRNEI--DKRIQEKEEEFDNTR 1587
Query: 5353 ERSNRDYKAKITELESGAQSRARAQMAA--LEAKVQYLEDQLNVEGQEKTAANRAARRLE 5526
R ++ LE+ A+ +A A LE + LE L+ + K + +R +
Sbjct: 1588 RNHQRALESMQASLEAEAKGKADAMRIKKKLEQDINELEVALDASNRGKAEMEKTVKRYQ 1647
Query: 5527 KRLNDTTQQFEDEKR----------------------------ANEQAKELLEKSNLKNR 5622
+++ + E+E+R A EQA+ + S+ +
Sbjct: 1648 QQIREMQTSIEEEQRQRDEARESYNMAERRCTLMSGEVEELRAALEQAERARKASDNELA 1707
Query: 5623 NLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
+ +++E ++S + + R ++ + + + +++ EL
Sbjct: 1708 DANDRVNELTSQVSSVQGQKRKLEGDINAMQTDLDEMHGEL 1748
Score = 166 bits (420), Expect = 6e-39
Identities = 157/856 (18%), Positives = 366/856 (42%), Gaps = 52/856 (6%)
Frame = +1
Query: 3310 NVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATM 3489
++ +++M++ +D+++ED+ + R K E+ + V L + K D+ ++
Sbjct: 841 SIARQEEEMKEQLKQMDKMKEDLA--KTERIKKELEEQNVT--LLEQKNDLFLQLQT--- 893
Query: 3490 LQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEK 3669
L+D M ++E V K+ QKA F Q++EL +++ + + LE
Sbjct: 894 LEDSMGDQEERVE---------------KLIMQKADFESQIKELEERLLDEEDAAADLEG 938
Query: 3670 QQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEH---------- 3819
+ + + + A++ ++I L+ + ++ + + + +Q +++ DEH
Sbjct: 939 IKKKMEADNANLKKDIGDLENTLQKAEQDKAHKDNQISTLQGEISQQDEHIGKLNKEKKA 998
Query: 3820 ----KRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL 3987
+ D L+ D+ +HLN+++ + E A ++ L
Sbjct: 999 LEEANKKTSDSLQAEEDKCNHLNKLKAKLEQALDELEDNLEREKKVR------------- 1045
Query: 3988 KIANINRA-RQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVN--QQ 4158
++ +A R++E + + + E+ E ++ LE+ + K E+ N Q
Sbjct: 1046 --GDVEKAKRKVEQDLKSTQENVEDLERVKRELEENVRRKEAEISSLNSKLEDEQNLVSQ 1103
Query: 4159 LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKR 4338
L+ K+ +E L+++LE A+ ++ + + ++ +ELE+ L+ + +
Sbjct: 1104 LQRKIKELQARIEELEEELEAERNARAKVEKQRAELNRELEELGERLDEAGGATSAQIEL 1163
Query: 4339 QKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLS-LLNEVDIMKEHLEESDRVRRS 4515
KK E+++ + R +++A L +A LR + + + ++VD +++ +S++ ++
Sbjct: 1164 NKKREAELLKIRRDLEEASLQHEAQISALRKKHQDAANEMADQVDQLQKVKSKSEKEKQQ 1223
Query: 4516 LQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVT 4695
L+ E++D + KN EK + E++++D+ ++E+ + ++ + + RL+
Sbjct: 1224 LRSEVEDLQAQIQHISKNKGCSEKVMKQFESQMSDLNARLEDSQRSINELQSQKSRLQAE 1283
Query: 4696 NQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGE 4875
N L + + A V ++EK + L Q+ D LE E R +S K++N++
Sbjct: 1284 NSDLTRQLEDAEHRVSVLSKEKSQ-LSSQLEDARRSLEEETRARS-------KLQNEVRN 1335
Query: 4876 LEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAE 5055
+ ++ + EE +++K D+
Sbjct: 1336 MHADMDAIRE---------------------QLEEEQESKSDV----------------- 1357
Query: 5056 REQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSE---EKRRLEAKIAQXXXXXXXX 5226
+ QL +AN + Q R + ++G + E +KR+L K+++
Sbjct: 1358 QRQLSKANNEIQQWRSKF----------ESEGANRTEELEDQKRKLLGKLSEAEQTTEAA 1407
Query: 5227 QSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES-- 5400
+ C + + Q +LE ++ ++ + E ++++ +++ +++AK+ L+S
Sbjct: 1408 NAKCSALEKAKSRLQQELEDMSIEVDRANASVNQMEKKQRAFDKTTAEWQAKVNSLQSEL 1467
Query: 5401 -GAQSRAR---AQMAALEAKVQY---------------------LEDQLNVEGQEKTAAN 5505
+Q +R A++ ++A ++ L DQL+ G+ +
Sbjct: 1468 ENSQKESRGYSAELYRIKASIEEYQDSIGALRRENKNLADEIHDLTDQLSEGGRSTHELD 1527
Query: 5506 RAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLD----EAEDEMSRER 5673
+A RRLE + E+ + A EQ + + ++ L+ +R ++D E E+E R
Sbjct: 1528 KARRRLEMEKEELQAALEEAEGALEQEEAKVMRAQLEIATVRNEIDKRIQEKEEEFDNTR 1587
Query: 5674 TKHRNVQREADDLLDA 5721
H+ L+A
Sbjct: 1588 RNHQRALESMQASLEA 1603
>gi|5817598|gb|AAD52842.1| myosin heavy chain [Pecten maximus]
Length = 1940
Score = 1179 bits (3051), Expect = 0.0
Identities = 666/1919 (34%), Positives = 1079/1919 (55%), Gaps = 18/1919 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
D QYL V R + T AA+ +K CWVPD+ EGF I+ DE+ V++ +
Sbjct: 9 DFQYLAVDRKKLMKEQT-AAFDGKKNCWVPDEKEGFAPAEIQSSKGDEITVKITSDNSTR 67
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
T+ +DD+Q NPPKF+K+EDM+ +TYLNEASVLHNL+ RY S LIYTYSGLFC+ +NPY+
Sbjct: 68 TVKKDDIQSMNPPKFEKLEDMANMTYLNEASVLHNLRSRYTSGLIYTYSGLFCIAVNPYR 127
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
+LPIY++ +I +++GK++ E+PPH+F++AD AY++M+ +RE+QS L TGESGAGKTENTK
Sbjct: 128 RLPIYTDSVISKYRGKRKTEIPPHLFSVADNAYQNMVTDRENQSCLITGESGAGKTENTK 187
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVI YLA VA A + K+ A G LE Q++QANP+LEA+GN+KT +
Sbjct: 188 KVIMYLAKVACAVKKKTDEEEASDK---------KQGSLEDQIIQANPVLEAYGNAKTTR 238
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
N+NSSRFGKFIRI+F +G I+GA+IE YLLEKSRV Q ER++HIFYQ+ + E
Sbjct: 239 NNNSSRFGKFIRIHFGPTGKIAGADIETYLLEKSRVTYQQSAERNYHIFYQVCSN-ALPE 297
Query: 907 KSEYLLEGVDN--YRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAV 1080
++ +L D+ Y F+ +T+ N+DDV+EF + I+GF +E S+ + +++
Sbjct: 298 LNDIMLVTPDSGLYSFINQGCLTVDNIDDVEEFKLCDEAFDILGFTKEEKQSMFKCTASI 357
Query: 1081 LLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQN 1260
L +G ++F Q + +QA +KV L G+ +L KA L+P++KVG E V K QN
Sbjct: 358 LHMGEMKFKQRPREEQAESDGTAEAEKVAFLCGINAGDLLKALLKPKVKVGTEMVTKGQN 417
Query: 1261 QEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQ 1440
Q +V A+AK+ Y+R+F WLV R+NK+LD T + +IG+LDIAGFEIFD NSFEQ
Sbjct: 418 LNQVTNSVGALAKSLYDRMFNWLVKRVNKTLD-TKAKRNYYIGVLDIAGFEIFDYNSFEQ 476
Query: 1441 ICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLD 1620
+CINYTNE+LQQ FN+ MFILEQEEY++EGI W+FIDFG+DLQ IDLIEKPMG+L++L+
Sbjct: 477 LCINYTNERLQQFFNHHMFILEQEEYKKEGIAWEFIDFGMDLQMCIDLIEKPMGILSILE 536
Query: 1621 EECLFPKANDKSFVEKLQKTH-NKHPKFIVPDMRSK-----SHFAVVHYAGRVDYSADQW 1782
EEC+FPKA+DKSF +KL + H K+ F P ++ +HF + HYAG V YS W
Sbjct: 537 EECMFPKADDKSFQDKLYQNHMGKNRMFTKPGKPTRPNQGPAHFELHHYAGNVPYSITGW 596
Query: 1783 LMKNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGM---FRT 1953
L KN DP+NENVV L+ S +P VA +++ E G + +KG F+T
Sbjct: 597 LDKNKDPINENVVSLLSVSKEPLVAELFRAPE---------EPVGGGGKKKKGKSSAFQT 647
Query: 1954 VSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICR 2133
+S +H+E L KLM L +T P FVRCIIPN K+ G +++ LVL QL+CNGVLEGIRICR
Sbjct: 648 ISAVHRESLNKLMKNLYSTHPSFVRCIIPNELKQPGLVDAELVLHQLQCNGVLEGIRICR 707
Query: 2134 QGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRT 2313
+GFP+R+ + EF+ RY IL P+ IP+ F+DGK K++T L +D YR+G +KVFF+
Sbjct: 708 KGFPSRLIYSEFKQRYSILAPNAIPQGFVDGKTVSEKILTGLQMDPAEYRLGTTKVFFKA 767
Query: 2314 GVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNW 2493
GVL +LEE RD +L+ +I FQA RG+L R+ Y N +L LRNW
Sbjct: 768 GVLGNLEEMRDERLSKIISMFQAHIRGYLIRKAYKKLQDQRIGLSVIQRNIRKWLVLRNW 827
Query: 2494 QWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVI 2673
QWW+L+ KVKPLL + R ++E++ + ++ KE L K E +E E++ ++ ++ +
Sbjct: 828 QWWKLYAKVKPLLSIARQEEEMKEQLKQMDKMKEDLAKTERIKKELEEQNVTLLEQKNDL 887
Query: 2674 QEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETV 2853
QLQ ++ + ++ +L + + E + ++ +RL ++K
Sbjct: 888 FLQLQTIEDSMGDQEERVEKLIMQKADFESQIKELEERLLDEEDAAADLEGIKKKMETDN 947
Query: 2854 RDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLT 3033
+ DK + D + +
Sbjct: 948 SNLKKDIGDLENTLQKAEQDKAHKDNQISTLQGEMAQQDEHIGKLNKEKKALEEANKKTS 1007
Query: 3034 TQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLA 3213
L E++ H K K +LE L ELE +L RE++ + ++E+ KRK+ +L+ +++++
Sbjct: 1008 ESLQAEEDKCNHLNKLKAKLEQALDELEDNLEREKKVRGDVEKAKRKVEQDLKSTQENVE 1067
Query: 3214 EKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERN 3393
+ EL + +++ E+ ++ ++E V+ +Q++++++Q I+EL E++E ERN
Sbjct: 1068 DLERVKRELEENVRRKEAEISTLNSKLEDEQNLVSQLQRKVKELQARIEELEEELEAERN 1127
Query: 3394 ARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTME 3570
AR K E R E+ +LE++ G+ LD+ AT Q +L +++ E+ +R +E+ E
Sbjct: 1128 ARAKVEKQRAELNRELEEL-GERLDEAGGATSAQIELNKKREAELLKIRRDLEEASLQHE 1186
Query: 3571 GKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADID 3750
+I + K E+ DQ++Q +K +S+LEK + +E D+ ++ ++ +
Sbjct: 1187 AQISALRKKHQDAANEMADQVDQLQKVKSKLEKDKKDIKREMDDLESQMTHNMKNKGCSE 1246
Query: 3751 KKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLA 3930
K K E+ + ++ A L +S L Q R + E L+R E+ EH + + + +
Sbjct: 1247 KVMKQFESQMSDLNARLEDSQRSINELQSQKSRLQAENSDLSRQLEDAEHRVSVLSKEKS 1306
Query: 3931 TAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQ 4110
TR + N R + + +A+ ++ EE + ++ +++++ A
Sbjct: 1307 QLGSQLEDARRSLEDETRARSKLQNEVRNMHADMDAVREQLEEEQESKSDVQRQLSKANN 1366
Query: 4111 GAGEARRKAE-ESVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELE 4281
+ R K E E N ++LE+ ++K L + ++ E + + ++K ++QQELE
Sbjct: 1367 EIQQWRSKFESEGANRTEELEDQKRKILGKLSEAEQTTEAANSKCSALEKAKSRLQQELE 1426
Query: 4282 DSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLN 4461
D S+E++ A+ EK+Q+ F+ AE + V + + +E R + +
Sbjct: 1427 DMSIEVDRANANVNQMEKKQRAFDKTTAEWQSKVNSLQSELENAQKESRGYSAELYRIKA 1486
Query: 4462 EVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE 4641
V+ ++ + R ++L E+ D + G++ HEL+KA+R LE E +++ +EE
Sbjct: 1487 SVEEYQDSIGSLRRENKNLADEIHDLTDQLSEGGRSTHELDKARRRLEMEKEELQAALEE 1546
Query: 4642 LEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKR 4821
E L+ E +R ++ +++E D+ I K+ E + RR + + ++ LE E +
Sbjct: 1547 AEGALEQEEAKVMRAQLEIATVRNEIDKRIQEKEEEFDNTRRNHQRALESMQASLEAEAK 1606
Query: 4822 GKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKED 5001
GK+ A+ +KK+E I ELE L+ +NR K E E Q EE ++ +++
Sbjct: 1607 GKADAMRIKKKLEQDINELEVALDASNRGKAEMEKTVKRYQQQIREMQTSIEEEQRQRDE 1666
Query: 5002 IAALLREADRKFRAVEAEREQLREANEGLMQARK-QXXXXXXXXXXXRAKGGGISS--EE 5172
A+R+ + E E+LR A E +ARK +SS +
Sbjct: 1667 ARESYNMAERRCTLMSGEVEELRAALEQAERARKASDNELADANDRVNELTSQVSSVQGQ 1726
Query: 5173 KRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSL 5352
KR+LE I + A ++ +KA ++ +L E+ + + E +++L
Sbjct: 1727 KRKLEGDINAMQTDLDEMHGELKGADERCKKAMADAARLADELRAEQDHSSQVEKVRKNL 1786
Query: 5353 ERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKR 5532
E ++++ ++ E E+ + + + LE++V LE +L+ E + + R+ ++R
Sbjct: 1787 ESQVKEFQIRLDEAEASSLKGGKKMIQKLESRVHELEAELDNEQRRHAETQKNMRKADRR 1846
Query: 5533 LNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
L + Q +++++ E+ +EL++K N K + +RQ++EAE+ + K+R Q E ++
Sbjct: 1847 LKELAFQADEDRKNQERLQELIDKLNAKIKTFKRQVEEAEEIAAINLAKYRKAQHELEE 1905
Score = 182 bits (463), Expect = 7e-44
Identities = 183/949 (19%), Positives = 380/949 (39%), Gaps = 5/949 (0%)
Frame = +1
Query: 2518 VKPLLQVTRT-DDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQE 2694
V+ L +V R ++ +R K+ E+ +L ++ + ++K+ ++ ++E+L+ E
Sbjct: 1066 VEDLERVKRELEENVRRKEAEISTLNSKLEDEQNLVSQLQRKVKELQARIEELEEELEAE 1125
Query: 2695 SENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXX 2874
A+++ R L N+ELE + + D R ++ +R
Sbjct: 1126 RNARAKVEKQRAEL---NRELEEL-GERLDEAGGATSAQIELNKKREAELLKIR------ 1175
Query: 2875 XXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHE 3054
+ + D D + ++ D E
Sbjct: 1176 ---RDLEEASLQHEAQISALRKKHQDAANEMADQVDQLQKVKSKLEKDKKDIKREMDDLE 1232
Query: 3055 ERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVE 3234
+ H +K KG E + + E ++ L A LEDS+ + E ++
Sbjct: 1233 SQMTHNMKNKGCSEKVMKQFESQMS--------------DLNARLEDSQRSINE----LQ 1274
Query: 3235 ELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEM 3414
++L + +L QL ++ V+++ K+ + + +++ R +E E AR+K +
Sbjct: 1275 SQKSRLQAENSDLSRQL---EDAEHRVSVLSKEKSQLGSQLEDARRSLEDETRARSKLQN 1331
Query: 3415 TRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKA 3594
R + A ++ V+ + ++ + + +Q +S+ + E+ + E ++E+QK
Sbjct: 1332 EVRNMHADMDAVREQLEEEQESKSDVQRQLSKANNEIQQWRSKFESEGANRTEELEDQKR 1391
Query: 3595 KFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEA 3774
K ++ E E + S LEK +++ QE DM+ E+ A+ ++KK++ +
Sbjct: 1392 KILGKLSEAEQTTEAANSKCSALEKAKSRLQQELEDMSIEVDRANANVNQMEKKQRAFDK 1451
Query: 3775 HLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXX 3954
E Q+ + + EL + EE + + +++R
Sbjct: 1452 TTAEWQSKVNSLQSELENAQKESRGYSAELYRIKASVEEYQDSIGSLRRENKNLADEIHD 1511
Query: 3955 XXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRK 4134
R R+LE EK L EEAEG E ++ A+ R +
Sbjct: 1512 LTDQLSEGGRSTHELDKARRRLEMEKEELQAALEEAEGALEQEEAKVMRAQLEIATVRNE 1571
Query: 4135 AEESVNQQLEEL---RKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELEN 4305
++ + ++ EE R+ + R +E +Q LE K ++ KKK++Q++ + + L+
Sbjct: 1572 IDKRIQEKEEEFDNTRRNHQRALESMQASLEAEAKGKADAMRIKKKLEQDINELEVALDA 1631
Query: 4306 VRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEH 4485
+ EK K+++ Q+ E + ++++ RD + E R + EV+ ++
Sbjct: 1632 SNRGKAEMEKTVKRYQQQIREMQTSIEEEQRQRDEARESYNMAERRCTLMSGEVEELRAA 1691
Query: 4486 LEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIA 4665
LE+++R R++ EL D+ ++ V ++ KR LE ++N M+ ++E+ L+ A
Sbjct: 1692 LEQAERARKASDNELADANDRVNELTSQVSSVQGQKRKLEGDINAMQTDLDEMHGELKGA 1751
Query: 4666 EDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENEL-ENEKRGKSGAVS 4842
D R + + + A ++ RA + + E+ R+ L Q+++ + L E E G
Sbjct: 1752 -DERCKKAMADAARLADELRAEQDHSSQVEKVRKNLESQVKEFQIRLDEAEASSLKGGKK 1810
Query: 4843 HRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLRE 5022
+K+E+++ ELE +L+ R E +R+
Sbjct: 1811 MIQKLESRVHELEAELDNEQRRHAETQKN----------------------------MRK 1842
Query: 5023 ADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQ 5202
ADR+ + + + ++ R+ E L + +L AKI
Sbjct: 1843 ADRRLKELAFQADEDRKNQERLQELID-------------------------KLNAKIKT 1877
Query: 5203 XXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQS 5349
+ + + K RKAQ +LE+ + QK A+ +S
Sbjct: 1878 FKRQVEEAEEIAAINLAKYRKAQHELEEAEERADTADSTLQKFRAKSRS 1926
Score = 177 bits (450), Expect = 2e-42
Identities = 187/941 (19%), Positives = 405/941 (42%), Gaps = 59/941 (6%)
Frame = +1
Query: 3100 QLHELEQDLNRERQYKSELEQHKRKLLAELED---SKDHLAEKMGKVEELNNQLMKRDEE 3270
Q+ ++++DL + + K ELE+ LL + D + + MG EE +L+ + +
Sbjct: 855 QMDKMKEDLAKTERIKKELEEQNVTLLEQKNDLFLQLQTIEDSMGDQEERVEKLIMQKAD 914
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ Q+ +E L+ ++ D ++ +++ MET+ N+ K ++ E L+K
Sbjct: 915 FESQIKELEER-----LLDEE--DAAADLEGIKKKMETD-NSNLKKDIGDLENT--LQKA 964
Query: 3451 KGDVLDKVDEATMLQDLMSRKDEEV---NATKRAIEQIQHTMEGKIEEQ----------K 3591
+ D K ++ + LQ M+++DE + N K+A+E+ ++ + K
Sbjct: 965 EQDKAHKDNQISTLQGEMAQQDEHIGKLNKEKKALEEANKKTSESLQAEEDKCNHLNKLK 1024
Query: 3592 AKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHE 3771
AK + ++EL D +E+ KK R +EK + + +Q+ + + L+ + ++++ + E
Sbjct: 1025 AKLEQALDELEDNLEREKKVRGDVEKAKRKVEQDLKSTQENVEDLERVKRELEENVRRKE 1084
Query: 3772 AHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXX 3951
A + + + L E ++ L+ QL+R EL R+ E EE A R
Sbjct: 1085 AEISTLNSKL----EDEQNLVSQLQRKVKELQA--RIEELEEELEAERNARAKVEKQRAE 1138
Query: 3952 XXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARR 4131
RL A + Q+E L++K EAE L+ RR
Sbjct: 1139 LNRELEELGERLDEAGGATSAQIE------LNKKREAELLKI----------------RR 1176
Query: 4132 KAEESVNQ---QLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
EE+ Q Q+ LRKK+ + Q+++ + K ++ + KK I++E++D ++
Sbjct: 1177 DLEEASLQHEAQISALRKKHQDAANEMADQVDQLQKVKSKLEKDKKDIKREMDDLESQMT 1236
Query: 4303 NVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKE 4482
+ + SEK K+FESQM++ + L D EL+ +++R+ + E +
Sbjct: 1237 HNMKNKGCSEKVMKQFESQMSD----LNARLEDSQRSINELQSQKSRLQA---ENSDLSR 1289
Query: 4483 HLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQM----EELED 4650
LE+++ L +E S +D +++ + +A+ L+ E+ +M M E+LE+
Sbjct: 1290 QLEDAEHRVSVLSKEKSQLGSQLEDARRSLEDETRARSKLQNEVRNMHADMDAVREQLEE 1349
Query: 4651 NLQIAEDARLRLEVTN---QALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKR 4821
+ D + +L N Q +S+ + +N+ E E+++R +L ++ + E E
Sbjct: 1350 EQESKSDVQRQLSKANNEIQQWRSKFESEGANRTEELEDQKRKILGKLSEAEQTTEAANS 1409
Query: 4822 GKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKED 5001
S + +++ ++ ++ +++ AN + E+Q + + E+
Sbjct: 1410 KCSALEKAKSRLQQELEDMSIEVDRANANVNQMEKKQRAFDKTTAEWQSKVNSLQSELEN 1469
Query: 5002 IAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSE---E 5172
R + ++A E+ +++ L + K ++GG + E
Sbjct: 1470 AQKESRGYSAELYRIKASVEEYQDSIGSLRRENKNLADEIHDLTDQLSEGGRSTHELDKA 1529
Query: 5173 KRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSL 5352
+RRLE + + + E K +AQ+++ + ++ ++ + +K E +
Sbjct: 1530 RRRLEMEKEELQAALEEAEGALEQEEAKVMRAQLEIATVRNEI--DKRIQEKEEEFDNTR 1587
Query: 5353 ERSNRDYKAKITELESGAQSRARAQMAA--LEAKVQYLEDQLNVEGQEKTAANRAARRLE 5526
R ++ LE+ A+ +A A LE + LE L+ + K + +R +
Sbjct: 1588 RNHQRALESMQASLEAEAKGKADAMRIKKKLEQDINELEVALDASNRGKAEMEKTVKRYQ 1647
Query: 5527 KRLNDTTQQFEDEKR----------------------------ANEQAKELLEKSNLKNR 5622
+++ + E+E+R A EQA+ + S+ +
Sbjct: 1648 QQIREMQTSIEEEQRQRDEARESYNMAERRCTLMSGEVEELRAALEQAERARKASDNELA 1707
Query: 5623 NLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
+ +++E ++S + + R ++ + + + +++ EL
Sbjct: 1708 DANDRVNELTSQVSSVQGQKRKLEGDINAMQTDLDEMHGEL 1748
Score = 160 bits (405), Expect = 3e-37
Identities = 155/856 (18%), Positives = 366/856 (42%), Gaps = 52/856 (6%)
Frame = +1
Query: 3310 NVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATM 3489
++ +++M++ +D+++ED+ + R K E+ + V L + K D+ ++
Sbjct: 841 SIARQEEEMKEQLKQMDKMKEDLA--KTERIKKELEEQNVT--LLEQKNDLFLQLQT--- 893
Query: 3490 LQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEK 3669
++D M ++E V K+ QKA F Q++EL +++ + + LE
Sbjct: 894 IEDSMGDQEERVE---------------KLIMQKADFESQIKELEERLLDEEDAAADLEG 938
Query: 3670 QQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEH---------- 3819
+ + + + +++ ++I L+ + ++ + + + +Q +A+ DEH
Sbjct: 939 IKKKMETDNSNLKKDIGDLENTLQKAEQDKAHKDNQISTLQGEMAQQDEHIGKLNKEKKA 998
Query: 3820 ----KRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL 3987
+ + L+ D+ +HLN+++ + E A ++ L
Sbjct: 999 LEEANKKTSESLQAEEDKCNHLNKLKAKLEQALDELEDNLEREKKVR------------- 1045
Query: 3988 KIANINRA-RQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVN--QQ 4158
++ +A R++E + + + E+ E ++ LE+ + K E+ N Q
Sbjct: 1046 --GDVEKAKRKVEQDLKSTQENVEDLERVKRELEENVRRKEAEISTLNSKLEDEQNLVSQ 1103
Query: 4159 LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKR 4338
L+ K+ +E L+++LE A+ ++ + + ++ +ELE+ L+ + +
Sbjct: 1104 LQRKVKELQARIEELEEELEAERNARAKVEKQRAELNRELEELGERLDEAGGATSAQIEL 1163
Query: 4339 QKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLS-LLNEVDIMKEHLEESDRVRRS 4515
KK E+++ + R +++A L +A LR + + + ++VD +++ + ++ ++
Sbjct: 1164 NKKREAELLKIRRDLEEASLQHEAQISALRKKHQDAANEMADQVDQLQKVKSKLEKDKKD 1223
Query: 4516 LQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVT 4695
+++E+ D S KN EK + E++++D+ ++E+ + ++ + + RL+
Sbjct: 1224 IKREMDDLESQMTHNMKNKGCSEKVMKQFESQMSDLNARLEDSQRSINELQSQKSRLQAE 1283
Query: 4696 NQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGE 4875
N L + + A V ++EK + L Q+ D LE+E R +S K++N++
Sbjct: 1284 NSDLSRQLEDAEHRVSVLSKEKSQ-LGSQLEDARRSLEDETRARS-------KLQNEVRN 1335
Query: 4876 LEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAE 5055
+ ++ + EE +++K D+
Sbjct: 1336 MHADMDAVRE---------------------QLEEEQESKSDV----------------- 1357
Query: 5056 REQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSE---EKRRLEAKIAQXXXXXXXX 5226
+ QL +AN + Q R + ++G + E +KR++ K+++
Sbjct: 1358 QRQLSKANNEIQQWRSKF----------ESEGANRTEELEDQKRKILGKLSEAEQTTEAA 1407
Query: 5227 QSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES-- 5400
S C + + Q +LE ++ ++ + E ++++ +++ ++++K+ L+S
Sbjct: 1408 NSKCSALEKAKSRLQQELEDMSIEVDRANANVNQMEKKQRAFDKTTAEWQSKVNSLQSEL 1467
Query: 5401 -GAQSRAR---AQMAALEAKVQY---------------------LEDQLNVEGQEKTAAN 5505
AQ +R A++ ++A V+ L DQL+ G+ +
Sbjct: 1468 ENAQKESRGYSAELYRIKASVEEYQDSIGSLRRENKNLADEIHDLTDQLSEGGRSTHELD 1527
Query: 5506 RAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLD----EAEDEMSRER 5673
+A RRLE + E+ + A EQ + + ++ L+ +R ++D E E+E R
Sbjct: 1528 KARRRLEMEKEELQAALEEAEGALEQEEAKVMRAQLEIATVRNEIDKRIQEKEEEFDNTR 1587
Query: 5674 TKHRNVQREADDLLDA 5721
H+ L+A
Sbjct: 1588 RNHQRALESMQASLEA 1603
>gi|45383005|ref|NP_989918.1| myosin heavy chain [Gallus gallus]
gi|17907763|dbj|BAB79445.1| myosin heavy chain [Gallus gallus]
Length = 1941
Score = 1179 bits (3050), Expect = 0.0
Identities = 688/1897 (36%), Positives = 1076/1897 (56%), Gaps = 19/1897 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K W+PD+ E ++ IK T +V VE D +V + D++Q NPPKFD IEDM+
Sbjct: 34 KKRAWIPDEKEAYIEVEIKESTGGKVTVETKDKQTRV-VKEDELQAMNPPKFDMIEDMAM 92
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LT+LNEASVL+NLK RY +IYTYSGLFCV INPYK LP+Y+ ++ +KGK+R E PP
Sbjct: 93 LTHLNEASVLYNLKRRYSHWMIYTYSGLFCVTINPYKWLPVYTAPVVAAYKGKRRSEAPP 152
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVA--GATRNKSLNAA 609
HI++IAD AY ML+ RE+QS+L TGESGAGKT NTK+VIQY A VA G T K + A
Sbjct: 153 HIYSIADNAYNDMLRNRENQSMLITGESGAGKTVNTKRVIQYFAIVAALGDTPGKKVAAL 212
Query: 610 AQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYI 789
A + G LE Q+++ANP +EAFGN+KT++NDNSSRFGKFIRI+F SG +
Sbjct: 213 ATKT----------GGTLEDQIIEANPAMEAFGNAKTIRNDNSSRFGKFIRIHFGPSGKL 262
Query: 790 SGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRG 963
+ A+I+ YLLEKSRV+ Q ERS+HI+YQIL G E + LL ++ +Y F
Sbjct: 263 ASADIDIYLLEKSRVIFQQPKERSYHIYYQILSG-KKPELQDMLLLSLNPYDYHFCSQGV 321
Query: 964 ITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQD 1143
T+ N+DD +E +T ++M I+GF++DE ++V A++ GN++F Q+++ +QA
Sbjct: 322 TTVDNLDDGEELMATDHAMDILGFSNDEKYGSYKIVGAIMHFGNMKFKQKQREEQAEADG 381
Query: 1144 DRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFK 1323
K +L+G+ +L K L PR+KVG E+V K QN EQ +AV A+AKA+Y+R+FK
Sbjct: 382 TESADKAAYLMGISSADLIKGLLHPRVKVGNEYVTKGQNVEQVVYAVGALAKATYDRMFK 441
Query: 1324 WLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFIL 1503
WLVTRINK+LD T FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF+L
Sbjct: 442 WLVTRINKTLD-TKLARQFFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVL 500
Query: 1504 EQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH 1683
EQEEY++EGIEW FIDFGLDLQ IDLIEKP+G+L++L+EEC+FPKA+D SF KL H
Sbjct: 501 EQEEYKKEGIEWVFIDFGLDLQACIDLIEKPLGILSILEEECMFPKASDMSFKAKLYDNH 560
Query: 1684 -NKHPKFIV--PDMRSK--SHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDP 1848
K P F PD + K +HF +VHYAG V Y+ WL KN DPLNE VV + Q S +
Sbjct: 561 LGKSPNFQKPRPDKKRKYEAHFELVHYAGVVPYNIIGWLDKNKDPLNETVVAVFQKSQNK 620
Query: 1849 FVAGIWKDAEFAGICAAEMNETAFGMRSRK-GMFRTVSQLHKEQLTKLMTTLRNTSPHFV 2025
+A ++++ + G + E ++ + +K F+TVSQLHKE L KLMT LR+T PHFV
Sbjct: 621 LLASLYEN--YVGSSSEEPHKPGSKEKRKKAASFQTVSQLHKENLNKLMTNLRSTQPHFV 678
Query: 2026 RCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVI 2205
RCIIPN K G +++ LVL QLRCNGVLEGIRICR+GFPNR+ + +F+ RY IL P I
Sbjct: 679 RCIIPNETKTPGAMDAFLVLHQLRCNGVLEGIRICRKGFPNRILYADFKQRYRILNPAAI 738
Query: 2206 PKN-FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQA 2382
P + F+D +++ K++++L++D + Y+ G +KVFF+ G+L LEE RD +L ++ QA
Sbjct: 739 PDDKFVDSRKATEKLLSSLELDHSQYKFGHTKVFFKAGLLGMLEEMRDERLAKILTMLQA 798
Query: 2383 QCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIR 2562
+ RG L R Y N A+ ++NW W +LF K+KPLL+ +T+ E+
Sbjct: 799 RIRGHLMRIEYQKIISRREALYTIQWNIRAFNAVKNWSWMKLFFKIKPLLKSAQTEKEMS 858
Query: 2563 AKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQT 2742
+E + KE L K E +E E+K +I E+ + QLQ E +N A+ ++ L
Sbjct: 859 TLKEEFQKLKEALEKSEAKRKELEEKQVSMIQEKNDLALQLQAEQDNLADAEERCDLLIK 918
Query: 2743 RNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTN 2922
+LE V ++ +R+ +RK + + +K
Sbjct: 919 SKIQLEAKVKELTERVEDEEEMNADLTAKKRKLEDECAELKKDIDDLEITLAKVEKEKHA 978
Query: 2923 VDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQ 3102
+ + L E++ KAK +LE Q
Sbjct: 979 TENKVKNLIEEMAALDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQ 1038
Query: 3103 LHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQ 3282
+ +LE L +E++ + +LE+ KRKL +L+ +++ + + ++L +L K+D E+
Sbjct: 1039 VDDLESSLEQEKKIRMDLERAKRKLEGDLKLTQESVMDLENDKQQLEEKLKKKDFEMSQL 1098
Query: 3283 LTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDV 3462
+R +++ +QK+++++Q I+EL E++E ER AR K E R EV +LE++ +
Sbjct: 1099 NSRIEDQQVTEAQLQKKIKELQARIEELEEELEAERAARAKVEKQRAEVSRELEEL-SER 1157
Query: 3463 LDKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQ 3639
L++ AT Q M++K E E +R +E+ E + K + V EL +QI+
Sbjct: 1158 LEEAGGATSAQLEMNKKREVEFLKLRRDLEEATLQHESTAAALRKKHADSVAELSEQIDN 1217
Query: 3640 HKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEH 3819
++ + +LEK++++ E D++ I L ++A+ +K + +E L E ++ + E
Sbjct: 1218 LQRVKQKLEKEKSEMKMEVDDLSSNIEYLTKNKANAEKLCRTYEDQLSEAKSKVDELQRQ 1277
Query: 3820 KRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIAN 3999
+ Q R + E L+R+ EE+E + R + T+ K A
Sbjct: 1278 LTDVSTQRGRLQTENGELSRLLEEKESFINQLSRGKTSFTQTIEELKRQLEEETKSKNAL 1337
Query: 4000 INRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKK 4179
+ + + + L ++ EE ++ L++ + A + R K E Q+ EEL +
Sbjct: 1338 AHALQASRHDCDLLREQYEEEVEAKSELQRNLSKANAEVAQWRTKYETDAIQRTEELEEA 1397
Query: 4180 NLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKF 4350
+ LQ+ E E A + + ++K ++Q E+ED S++LE ++ +K+Q+ F
Sbjct: 1398 KKKLAIRLQEAEEAVEAAHAKCSSLEKTKHRLQTEIEDLSVDLERANSACAALDKKQRNF 1457
Query: 4351 ESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQEL 4530
+ +AE + ++ + +A +E R T + L N + ++LE R ++LQ+E+
Sbjct: 1458 DRILAEWKQKYEETQAELEASQKESRSLSTELFKLKNAYEESLDNLETLKRENKNLQEEI 1517
Query: 4531 QDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALK 4710
D GK +HELEK K++LE E +D++ +EE E L+ E LR+++ +K
Sbjct: 1518 ADLTDQISMSGKTIHELEKLKKALENEKSDIQAALEEAEGALEHEESKTLRIQLELNQIK 1577
Query: 4711 SESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
++ DR ++ KD E E RR + + ++ L+ E R K+ AV RKK+E + E+E QL
Sbjct: 1578 ADVDRKLAEKDEEFENLRRNHQRAMDSMQATLDAEARAKNEAVRLRKKMEGDLNEMEIQL 1637
Query: 4891 EVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLR 5070
ANR E+ + QIE ++ ++ +D+ +R+ + AE E+LR
Sbjct: 1638 SHANRQAAEFQKLGRQLQAQIKDLQIELDDTQRQNDDLKEQAAALERRNNLLLAEVEELR 1697
Query: 5071 EANEGLMQARK----QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNC 5238
A E ++RK + ++ G+ + +K++LE I+Q C
Sbjct: 1698 AALEQAERSRKLAEQELLEATERVNLLHSQNTGLIN-QKKKLETDISQLSSEVEDAVQEC 1756
Query: 5239 ELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRA 5418
A +K +KA + +L E+ + E K+++E++ +D + ++ E E A
Sbjct: 1757 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQMRLDEAEQIALKGG 1816
Query: 5419 RAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELL 5598
+ Q+ LEA+V+ LE +L++E ++ A + R+ E+R+ + + Q E++++ + ++L+
Sbjct: 1817 KKQIQKLEARVRELEGELDMEQKKMAEAQKGIRKYERRIKELSYQTEEDRKNLTRMQDLI 1876
Query: 5599 EKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+K K ++ +RQ +EAE + + K+R VQ E DD
Sbjct: 1877 DKLQSKVKSYKRQFEEAEQQANSNLVKYRKVQHELDD 1913
Score = 143 bits (360), Expect = 6e-32
Identities = 166/880 (18%), Positives = 361/880 (40%), Gaps = 73/880 (8%)
Frame = +1
Query: 3325 QKQMRDMQTTIDELREDMETERNARNKAE-------MTRREVVAQLEKVKGDVLDKVDEA 3483
+K+M ++ +L+E +E R + E + ++ QL+ + ++ D +
Sbjct: 854 EKEMSTLKEEFQKLKEALEKSEAKRKELEEKQVSMIQEKNDLALQLQAEQDNLADAEERC 913
Query: 3484 TMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQL 3663
+L + + +V +E + M + +K K + EL I+ + +++
Sbjct: 914 DLLIKSKIQLEAKVKELTERVED-EEEMNADLTAKKRKLEDECAELKKDIDDLEITLAKV 972
Query: 3664 EKQQNQADQERADMAQEIALLQASRADIDKKRK-IHEAHLMEIQANLAESDEHKRTLIDQ 3840
EK+++ + + ++ +E+A L A + K++K + EAH + AE D+ TL
Sbjct: 973 EKEKHATENKVKNLIEEMAALDEIIAKLTKEKKALQEAHQQALDDLQAEEDK-VNTLTKA 1031
Query: 3841 LERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQL 4020
+ ++D L E+E+ +++R LK+ L
Sbjct: 1032 KVKLEQQVDDLESSLEQEKKIRMDLERAKRKLEGD-------------LKLTQ-ESVMDL 1077
Query: 4021 EDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEH 4200
E++K L ++ ++ + + L I E ++ E + ++++EL+ + +E
Sbjct: 1078 ENDKQQLEEKLKKKDFEMSQLNSRI--------EDQQVTEAQLQKKIKELQAR----IEE 1125
Query: 4201 LQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVA 4380
L+++LE A+ ++ + + ++ +ELE+ S LE + + KK E + + R
Sbjct: 1126 LEEELEAERAARAKVEKQRAEVSRELEELSERLEEAGGATSAQLEMNKKREVEFLKLRRD 1185
Query: 4381 VQKALLDRDAMSQELRDRET-RVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDD 4557
+++A L ++ + LR + V L ++D ++ ++ ++ + ++ E+ D SN +
Sbjct: 1186 LEEATLQHESTAAALRKKHADSVAELSEQIDNLQRVKQKLEKEKSEMKMEVDDLSSNIEY 1245
Query: 4558 FGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISN 4737
KN EK R+ E +L++ + +++EL+ L R RL+ N E R +
Sbjct: 1246 LTKNKANAEKLCRTYEDQLSEAKSKVDELQRQLTDVSTQRGRLQTEN----GELSRLLEE 1301
Query: 4738 KDVEAEEKRRG---LLKQIRDLENELENEKRGKSGAVSHRKKIENQIGEL-----EQQLE 4893
K+ + RG + I +L+ +LE E + K+ A++H + +L E+++E
Sbjct: 1302 KESFINQLSRGKTSFTQTIEELKRQLEEETKSKN-ALAHALQASRHDCDLLREQYEEEVE 1360
Query: 4894 VANRLKEEYXXXXXXXXXXXXEYQIEC----EEARQAKEDIAALLREADRKFRAVEAERE 5061
+ L+ +Y+ + EE +AK+ +A L+EA+ A A+
Sbjct: 1361 AKSELQRNLSKANAEVAQWRTKYETDAIQRTEELEEAKKKLAIRLQEAEEAVEAAHAKCS 1420
Query: 5062 QLRE------------------ANEGLMQARKQXXXXXXXXXXXRAKGGGISSE------ 5169
L + AN K+ + K +E
Sbjct: 1421 SLEKTKHRLQTEIEDLSVDLERANSACAALDKKQRNFDRILAEWKQKYEETQAELEASQK 1480
Query: 5170 EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQS 5349
E R L ++ + N E + + Q ++ +T +SM + E K++
Sbjct: 1481 ESRSLSTELFKLKNAYEESLDNLETLKRENKNLQEEIADLTDQISMSGKTIHELEKLKKA 1540
Query: 5350 LERSNRDYKAKITELESGAQS------RARAQMAALEAKVQY------------------ 5457
LE D +A + E E + R + ++ ++A V
Sbjct: 1541 LENEKSDIQAALEEAEGALEHEESKTLRIQLELNQIKADVDRKLAEKDEEFENLRRNHQR 1600
Query: 5458 ----LEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRN 5625
++ L+ E + K A R +++E LN+ Q R + ++L + + ++
Sbjct: 1601 AMDSMQATLDAEARAKNEAVRLRKKMEGDLNEMEIQLSHANRQAAEFQKLGRQLQAQIKD 1660
Query: 5626 LRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
L+ +LD+ + + + + ++R + LL E+L L
Sbjct: 1661 LQIELDDTQRQNDDLKEQAAALERRNNLLLAEVEELRAAL 1700
Score = 91.7 bits (226), Expect = 2e-16
Identities = 81/409 (19%), Positives = 176/409 (42%), Gaps = 14/409 (3%)
Frame = +1
Query: 3103 LHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQ 3282
+HELE+ K LE K + A LE+++ L + K + +L + ++ +
Sbjct: 1531 IHELEK-------LKKALENEKSDIQAALEEAEGALEHEESKTLRIQLELNQIKADVDRK 1583
Query: 3283 LTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDV 3462
L DEE N+ R+ Q +D ++ ++ E A+N+A R+++ L +++ +
Sbjct: 1584 LAEKDEEFENLR------RNHQRAMDSMQATLDAEARAKNEAVRLRKKMEGDLNEMEIQL 1637
Query: 3463 LDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQH 3642
+A Q L + ++ + ++ Q + ++EQ A R+ L ++E+
Sbjct: 1638 SHANRQAAEFQKLGRQLQAQIKDLQIELDDTQRQNDD-LKEQAAALERRNNLLLAEVEEL 1696
Query: 3643 KKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHK 3822
+ Q E+ + A+QE + + + LL + + ++K E + ++ + + ++ +
Sbjct: 1697 RAALEQAERSRKLAEQELLEATERVNLLHSQNTGLINQKKKLETDISQLSSEVEDAVQEC 1756
Query: 3823 RT--------------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXX 3960
R + ++L++ +D HL R+++ E ++Q RL A
Sbjct: 1757 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQMRLDEAEQIALKGG 1816
Query: 3961 XXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAE 4140
++ + +E +K A E +G+R + E+ I E R+
Sbjct: 1817 KKQIQKLEARVRELEGELDMEQKKMA-----EAQKGIRKY-ERRIKELSYQTEEDRKNLT 1870
Query: 4141 ESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDS 4287
++++L K V+ ++Q EE+E L +K+Q EL+D+
Sbjct: 1871 -----RMQDLIDKLQSKVKSYKRQFEEAEQQANSNLVKYRKVQHELDDA 1914
Score = 68.9 bits (167), Expect = 1e-09
Identities = 95/483 (19%), Positives = 196/483 (39%), Gaps = 44/483 (9%)
Frame = +1
Query: 4435 ETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAEL 4614
E + +L E +KE LE+S+ R+ ELE+ + S+ E
Sbjct: 854 EKEMSTLKEEFQKLKEALEKSEAKRK---------------------ELEEKQVSMIQEK 892
Query: 4615 NDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDL 4794
ND+ +Q++ +DNL AE+ D I +K ++ E K +++L
Sbjct: 893 NDLALQLQAEQDNLADAEE--------------RCDLLIKSK-IQLEAK-------VKEL 930
Query: 4795 ENELENEKRGKSGAVSHRKKIENQIGELEQQLE-----VANRLKEEYXXXXXXXXXXXXE 4959
+E+E+ + + ++K+E++ EL++ ++ +A KE++
Sbjct: 931 TERVEDEEEMNADLTAKKRKLEDECAELKKDIDDLEITLAKVEKEKHATE---------- 980
Query: 4960 YQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXX 5139
+ + E++AAL D + E++ L+EA++ + +
Sbjct: 981 -----NKVKNLIEEMAAL----DEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKA 1031
Query: 5140 RAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTL 5319
+ K LE ++ + E ++++++K ++ LE+ L + L
Sbjct: 1032 KVK-----------LEQQV-----------DDLESSLEQEKKIRMDLERAKRKLEGDLKL 1069
Query: 5320 NQKT----EAEKQSLERSNRDYKAKITELESG------AQSRARAQMAALEAKVQYLEDQ 5469
Q++ E +KQ LE + ++++L S +++ + ++ L+A+++ LE++
Sbjct: 1070 TQESVMDLENDKQQLEEKLKKKDFEMSQLNSRIEDQQVTEAQLQKKIKELQARIEELEEE 1129
Query: 5470 LNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEA 5649
L E + + + + L + +++ E+ A E+ +K ++ LRR L+EA
Sbjct: 1130 LEAERAARAKVEKQRAEVSRELEELSERLEEAGGATSAQLEMNKKREVEFLKLRRDLEEA 1189
Query: 5650 ----EDEMSRERTKHR-----------NVQR--------------EADDLLDANEQLTRE 5742
E + R KH N+QR E DDL E LT+
Sbjct: 1190 TLQHESTAAALRKKHADSVAELSEQIDNLQRVKQKLEKEKSEMKMEVDDLSSNIEYLTKN 1249
Query: 5743 LMN 5751
N
Sbjct: 1250 KAN 1252
>gi|38014765|gb|AAH60471.1| LOC398083 protein [Xenopus laevis]
Length = 941
Score = 1178 bits (3048), Expect = 0.0
Identities = 589/934 (63%), Positives = 722/934 (77%), Gaps = 8/934 (0%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL V R V +P A WA +KL WVP + GF SIK E DE +VEL + ++ +
Sbjct: 8 KYLYVDRNFVNNPLAQADWAAKKLVWVPSEKNGFEAASIKEEVGDEAIVELAENGKKAKV 67
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDMSEL LNEASVLHNLK+RYYS LIYTYSGLFCVVINPYK L
Sbjct: 68 NKDDIQKMNPPKFSKVEDMSELACLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNL 127
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYSE+++E +KGKKRHEMPPHI+AI DTAYRSM+Q+REDQSILCTGESGAGKTENTKKV
Sbjct: 128 PIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKV 187
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
IQYLA+VA + ++K GELE QLLQANPILEAFGN+KTVKND
Sbjct: 188 IQYLAYVATSHKSKKDQ-----------------GELERQLLQANPILEAFGNAKTVKND 230
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFY ++ G KS
Sbjct: 231 NSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKDERTFHIFYYLMSGAGEHLKS 290
Query: 913 EYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 1092
+ LLE + YRFL N +T+P D F T+ +M+IMGF D+E + ++RVVSAVL LG
Sbjct: 291 DLLLEAYNKYRFLSNGHVTIPGQLDKDLFQETMEAMKIMGFTDEEQTGLLRVVSAVLQLG 350
Query: 1093 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA 1272
N+ F +E+ +DQA + D+ QKVCHLLG+ V + + L PRIKVGR+FV KAQ +EQA
Sbjct: 351 NIAFKKERNTDQASMPDNTAAQKVCHLLGINVNDFTRGILLPRIKVGRDFVQKAQTKEQA 410
Query: 1273 EFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICIN 1452
+FA+EA+AKASYER+F+WLV R+NK+LD+T RQGASFIGILDIAGFEIF++NSFEQ+CIN
Sbjct: 411 DFAIEALAKASYERMFRWLVMRVNKALDKTKRQGASFIGILDIAGFEIFELNSFEQLCIN 470
Query: 1453 YTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDE 1623
YTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP IDLIE+P G+LALLDE
Sbjct: 471 YTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPAGPPGILALLDE 530
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMD 1800
EC FPKA DKSFVEK+ + H KF P ++ K+ F+++HYAGRVDY AD+WL+KNMD
Sbjct: 531 ECWFPKATDKSFVEKVVQEQGSHSKFQKPKQLKDKADFSIIHYAGRVDYKADEWLLKNMD 590
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQLH 1968
PLN+NV L+ S+D FV+ +WKD + G+ A M++TA ++RKGMFRTV QL+
Sbjct: 591 PLNDNVATLLNQSSDKFVSELWKDVDRIVGLDQVAGMSDTALPGAFKTRKGMFRTVGQLY 650
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
KEQL+KLM TLRNT+P+FVRCIIPNHEKKSGK++++LVL+QLRCNGVLEGIRICRQGFPN
Sbjct: 651 KEQLSKLMATLRNTNPNFVRCIIPNHEKKSGKLDAHLVLDQLRCNGVLEGIRICRQGFPN 710
Query: 2149 RVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAH 2328
RV FQEFR RYEILTP+ IPK F+DGK++ MI AL++D+NLYRIGQSKVFFR+GVLAH
Sbjct: 711 RVVFQEFRQRYEILTPNAIPKGFMDGKQACVLMIRALELDSNLYRIGQSKVFFRSGVLAH 770
Query: 2329 LEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRL 2508
LEEERDLK+T +I++FQA CRG+L+R+ + N AYLKLRNWQWWRL
Sbjct: 771 LEEERDLKITDVIISFQACCRGYLARKAFARRQQQLTAMKVIQRNCAAYLKLRNWQWWRL 830
Query: 2509 FTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQ 2688
FTKVKPLLQ R D+E+ AK+ EL+ K+ + E E E + E+ +QEQLQ
Sbjct: 831 FTKVKPLLQANRFDEELHAKEVELQKIKDLQVSSEQKVSEMENVQMMLQQEKMQLQEQLQ 890
Query: 2689 QESENSAELDDIRGRLQTRNQELEYIVNDMRDRL 2790
E E AE +++R RL + QELE I++D+ R+
Sbjct: 891 AEIELCAEAEEMRARLANKKQELEEILHDLESRV 924
>gi|6708502|gb|AAD09454.2| superfast myosin heavy chain [Felis catus]
Length = 1945
Score = 1173 bits (3034), Expect = 0.0
Identities = 672/1904 (35%), Positives = 1076/1904 (56%), Gaps = 26/1904 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
++ CWV D+ EGF+ G I+ E D+V V+ V+ ++ VT+ +DDVQ+ NPPKF + DM++
Sbjct: 37 KRSCWVKDEKEGFIAGEIQSEQGDQVTVKTVN-NQTVTVKKDDVQQMNPPKFYQANDMAD 95
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
+T+LNEASVL+NL+ RY + IYTYSGLFCV +NPYK LPIY + +KGKKR EMPP
Sbjct: 96 MTFLNEASVLNNLRQRYTNMRIYTYSGLFCVTVNPYKWLPIYGARVANMYKGKKRTEMPP 155
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
H+F+I+D AY+ ML RE+QS+L TGESGAGKTENTKKVIQY A+V G + S
Sbjct: 156 HLFSISDNAYQDMLMNRENQSMLITGESGAGKTENTKKVIQYFANVGGTGKQSS------ 209
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
+ G LE Q++QANP+LEAFGN+KT++N+NSSRFGKFIRI+F +G ++G
Sbjct: 210 ----------DGKGSLEDQIIQANPVLEAFGNAKTIRNNNSSRFGKFIRIHFGTTGKLAG 259
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRFLVNRGIT-L 972
A+IE YLLEKSRV+ Q ER +HIFYQIL + LL V++G+T +
Sbjct: 260 ADIESYLLEKSRVISQQPAERGYHIFYQILSNKKPELIETLLLVPNPKEYHWVSQGVTVV 319
Query: 973 PNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRV 1152
N+DD +E T + ++GF+ DE I ++ ++ GN++F Q+ + +QA + V
Sbjct: 320 ENMDDGEELQITDVAFDVLGFSADEKIGIYKLTGGIMHFGNMKFKQKPREEQAEVDTTEV 379
Query: 1153 IQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLV 1332
KV HL+GL ELQK RPR+KVG EFV K QN EQ ++ A+ KA Y+++FKWLV
Sbjct: 380 ADKVAHLMGLNSGELQKGITRPRVKVGNEFVQKGQNMEQCHNSIGALGKAVYDKMFKWLV 439
Query: 1333 TRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQE 1512
RINK+LD T Q FIG+LDIAGFEIF+ NSFEQ+CIN+TNEKLQQ FN+ MF+LEQE
Sbjct: 440 VRINKTLD-TKMQRQFFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNHHMFVLEQE 498
Query: 1513 EYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NK 1689
EY+REGIEW FIDFGLDLQ IDL+EKPMG+ ++L+E+C+FPKA D +F L H K
Sbjct: 499 EYKREGIEWVFIDFGLDLQACIDLLEKPMGIFSILEEQCVFPKATDATFKAALYDNHLGK 558
Query: 1690 HPKFIVP----DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVA 1857
F+ P ++HF +VHYAG V Y+ WL KN DPLNE VVGL Q S+ +A
Sbjct: 559 SSNFLKPKGGKGKGPEAHFELVHYAGTVGYNITGWLEKNKDPLNETVVGLFQKSSLVLLA 618
Query: 1858 GIWKDAEFAGICAAEMNETAFGMRSRKG-MFRTVSQLHKEQLTKLMTTLRNTSPHFVRCI 2034
++K+ E A + ++G F TVS ++EQL KLM TL +T+PHFVRCI
Sbjct: 619 LLFKEEE----------APAGSKKQKRGSSFMTVSNFYREQLNKLMATLHSTAPHFVRCI 668
Query: 2035 IPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKN 2214
+PN K+SG ++++L++ QL CNGVLEGIRICR+GFPNR+ + EF+ RY++L P+VIP+
Sbjct: 669 VPNEFKQSGVVDAHLIMHQLACNGVLEGIRICRKGFPNRMQYPEFKQRYQVLNPNVIPQG 728
Query: 2215 FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRG 2394
F+D K++ ++ ++D+D N Y+IG +KVFFR G+LA LE+ R+ +L ++ Q + RG
Sbjct: 729 FVDNKKASELLLGSIDLDVNEYKIGHTKVFFRAGILAKLEDMREQRLAKIMTMLQCRLRG 788
Query: 2395 FLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDD 2574
FL R + N +L+LR W WW+L+ KVKPLL V R ++E++AK++
Sbjct: 789 FLMRIEFKKMLERRIGLKVIQRNTRKFLELRFWGWWKLYNKVKPLLNVARQEEEMKAKEE 848
Query: 2575 ELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQE 2754
ELR + ++ +E E+K+ + E+ + QLQ E EN + ++ ++ E
Sbjct: 849 ELRNAMCKTQELISRVKELEEKMATLSQEKNDLTIQLQAEQENLIDAEERLTQMMKTKME 908
Query: 2755 LEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQX 2934
LE ++DMR+RL +RK + D +K +D
Sbjct: 909 LESQISDMRERLEEEEGTAASLSATKRKLEGEMSDLKRDLEGLETTLAKMEKEKQALDHK 968
Query: 2935 XXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHEL 3114
+D+ L E++ H K +L Q+HEL
Sbjct: 969 VRTLTGDLSLREDSIAKLQKEKRALEELHQKTLDDLQAEEDKVNHLTKTNSKLSTQIHEL 1028
Query: 3115 EQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRY 3294
E + +E++ ++E+E+ +RK ++L+ + D+L E +L + KRD E+ ++Y
Sbjct: 1029 EDNWEQEKKIRAEVEKARRKAESDLKITIDNLNEMERSKLDLEEVVKKRDMEINSVNSKY 1088
Query: 3295 DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKV 3474
++E + + +Q+++++ Q I+EL E++E ER R K E R ++ LE + D L++
Sbjct: 1089 EDEQSLNSTLQRKLKEHQARIEELEEELEAERAMRAKVEKQRSDLSRDLEDL-SDRLEEA 1147
Query: 3475 DEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQ 3651
AT Q +RK E E+ +R +E+ E + K + + EL + +E ++
Sbjct: 1148 GGATSAQIEQNRKREAELLKLRRELEEAALQSEAAASTLRKKHTDSMAELTEHVENLQRV 1207
Query: 3652 RSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTL 3831
+++LEK ++ M EI L AS + K + EAH+ +++ +LAE++
Sbjct: 1208 KAKLEK-------DKQVMKAEIDDLNASMETVQKSKMNAEAHIRKLEDSLAEAN----AK 1256
Query: 3832 IDQLERSRDELD-----------HLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXX 3978
+ +LER++ E++ L+R EE + + R +
Sbjct: 1257 VAELERNQAEINAIRTRLQAENGELSREYEESQSRLNQILRIKTSLTSQVDDYKRQLDEE 1316
Query: 3979 TRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQ 4158
++ + + + + + + ++ EE +G ++ L++ + R K E Q+
Sbjct: 1317 SKSRSTAMVSLANTKHDLDLVKEQLEEEQGGKSELQRLVSKLNTEVTTWRTKYETDAIQR 1376
Query: 4159 LEELRKKNLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDS 4329
EEL + + LQ+ E +E A+ R + ++K+++Q E+ED +++LE A+
Sbjct: 1377 TEELEETKRKLAARLQEAEETAEAAQARAASLEKNKQRLQAEIEDLTIDLEKANAAAAAL 1436
Query: 4330 EKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVR 4509
+K+Q+ F+ +AE + ++ ++ D+ +E R T + + EHLE +
Sbjct: 1437 DKKQRVFDKMLAEWQQKCEELQVEVDSAQKECRMYMTESFKIKTAYEESLEHLESVKKEN 1496
Query: 4510 RSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLE 4689
++LQ+E+++ I + G++VHEL+K K+ LE E +++V +EE E +L++ E +R++
Sbjct: 1497 KTLQEEIKELIDQLGEGGRSVHELQKLKKKLEIEKEELQVALEEAESSLEVEESKVIRIQ 1556
Query: 4690 VTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQI 4869
+ +K++ DR I K+ E E R+ + I L+ LE E +G++ A+ +KK+E +
Sbjct: 1557 LELAQVKADIDRRIHEKEEEFEATRKNHQRAIESLQASLEAEAKGRAEALRLKKKMETDL 1616
Query: 4870 GELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVE 5049
E+E QL+ AN+ E + Q++ +E + E++ +R+ ++
Sbjct: 1617 NEMEIQLDHANKNNSELVKTLKRLEQQIKDLQMQMDEDARQHEELREQYNLQERRLSLLQ 1676
Query: 5050 AEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEE----KRRLEAKIAQXXXXX 5217
E E++R EG ++RK R I ++ KR+LE+ + +
Sbjct: 1677 TELEEVRAGLEGSERSRK-LLEQEVVEITERHNEVNIQNQSLLVVKRKLESDVQRISNEH 1735
Query: 5218 XXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELE 5397
S A ++ +KA ++ +L E+ E K++ E + +D +AK+ E E
Sbjct: 1736 EELISEFRSADERAKKAMTDAARMAEELRQEQDHCMHLEKIKKNYEITIKDLQAKMEEAE 1795
Query: 5398 SGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRAN 5577
A + + LEA+++ LE +L+ E ++ + R+ E+RL + Q E++ + N
Sbjct: 1796 QLALKGGKRTIMKLEARIKELETELDGEQKQHVETVKTLRKNERRLKELVFQTEEDHKTN 1855
Query: 5578 EQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
++ +EL+EK K + +RQ++EAE++ ++ ++R E DD
Sbjct: 1856 QRMQELVEKLQNKLKIYKRQIEEAEEQANQTLARYRKTVHELDD 1899
Score = 80.9 bits (198), Expect = 4e-13
Identities = 133/728 (18%), Positives = 274/728 (37%), Gaps = 135/728 (18%)
Frame = +1
Query: 2557 IRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRL 2736
++A+ D+L A+ E + K + + + +KL+ + E +L++ N AE++ IR RL
Sbjct: 1218 MKAEIDDLNASMETVQKSKMNAEAHIRKLEDSLAEANAKVAELER---NQAEINAIRTRL 1274
Query: 2737 QTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDK 2916
Q N EL + + RL+ + + D
Sbjct: 1275 QAENGELSREYEESQSRLNQILRIKTSLTSQVDDYKRQLDEESKSRSTAMVSLANTKHDL 1334
Query: 2917 TNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLE 3096
V + Q T D +R + + K +L
Sbjct: 1335 DLVKEQLEEEQGGKSELQRLVSKLNTEVTTWR------TKYETDAIQRTEELEETKRKLA 1388
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELED----------------SKDHLAEKM-- 3222
+L E E+ + + LE++K++L AE+ED K + +KM
Sbjct: 1389 ARLQEAEETAEAAQARAASLEKNKQRLQAEIEDLTIDLEKANAAAAALDKKQRVFDKMLA 1448
Query: 3223 ---GKVEELNNQLMKRDEELQHQLTR-------YDEESANVTLMQKQMRDMQTTIDELRE 3372
K EEL ++ +E + +T Y+E ++ ++K+ + +Q I EL +
Sbjct: 1449 EWQQKCEELQVEVDSAQKECRMYMTESFKIKTAYEESLEHLESVKKENKTLQEEIKELID 1508
Query: 3373 DM-------ETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ----------DL 3501
+ + + K E+ + E+ LE+ + + +V+E+ +++ D+
Sbjct: 1509 QLGEGGRSVHELQKLKKKLEIEKEELQVALEEAESSL--EVEESKVIRIQLELAQVKADI 1566
Query: 3502 MSR---KDEEVNATK----RAIEQIQHTME----GKIEEQKAK----------------- 3597
R K+EE AT+ RAIE +Q ++E G+ E + K
Sbjct: 1567 DRRIHEKEEEFEATRKNHQRAIESLQASLEAEAKGRAEALRLKKKMETDLNEMEIQLDHA 1626
Query: 3598 -------------FSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASR 3738
+Q+++L Q+++ +Q +L +Q N ++ + + E+ ++A
Sbjct: 1627 NKNNSELVKTLKRLEQQIKDLQMQMDEDARQHEELREQYNLQERRLSLLQTELEEVRAGL 1686
Query: 3739 ADIDKKRKIHEAHLMEIQANLAE----------------------SDEHKRTL------- 3831
++ RK+ E ++EI E S+EH+ +
Sbjct: 1687 EGSERSRKLLEQEVVEITERHNEVNIQNQSLLVVKRKLESDVQRISNEHEELISEFRSAD 1746
Query: 3832 -------------IDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXX 3972
++L + +D HL ++++ E ++Q ++ A
Sbjct: 1747 ERAKKAMTDAARMAEELRQEQDHCMHLEKIKKNYEITIKDLQAKMEEAEQLALKGGKRTI 1806
Query: 3973 XXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVN 4152
+I ++LE E + ++K+ E ++ + E R + + + N
Sbjct: 1807 MKLEARI------KELETELDG--EQKQHVETVKTLRKNE---RRLKELVFQTEEDHKTN 1855
Query: 4153 QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELED-------SSMELENVR 4311
Q+++EL +K ++ ++Q+EE+E + L +K EL+D + L +R
Sbjct: 1856 QRMQELVEKLQNKLKIYKRQIEEAEEQANQTLARYRKTVHELDDAEERAGMAETALNKLR 1915
Query: 4312 ASHRDSEK 4335
HR + K
Sbjct: 1916 TRHRVAGK 1923
>gi|34785893|gb|AAH57729.1| LOC398719 protein [Xenopus laevis]
Length = 941
Score = 1172 bits (3032), Expect = 0.0
Identities = 586/934 (62%), Positives = 719/934 (76%), Gaps = 8/934 (0%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL V R V +P A WA +KL WVP + GF SIK E DE +VEL + ++ +
Sbjct: 8 KYLYVDRNYVNNPLAQADWAAKKLVWVPSEKNGFEAASIKEEVGDEAIVELAENGKKAKV 67
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDMSEL LNEASVLHNLK+RYYS LIYTYSGLFCVVINPYK L
Sbjct: 68 NKDDIQKMNPPKFSKVEDMSELACLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNL 127
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYSE+++E +KGKKRHEMPPHI+AI DTAYRSM+Q+REDQSILCTGESGAGKTENTKKV
Sbjct: 128 PIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKV 187
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
IQYLA+VA + ++K GELE QLLQANPILEAFGN+KTVKND
Sbjct: 188 IQYLAYVATSHKSKKDQ-----------------GELERQLLQANPILEAFGNAKTVKND 230
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFY +L G +S
Sbjct: 231 NSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKDERTFHIFYYLLSGAGEHLQS 290
Query: 913 EYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 1092
+ LLE + YRFL N +T+P D F T+ +M+IMGF+D+E ++RV+S VL LG
Sbjct: 291 DLLLEAYNKYRFLSNGHVTIPGQLDKDLFQETMEAMKIMGFSDEEQIGLLRVISVVLQLG 350
Query: 1093 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA 1272
N+ F +E+ +DQA + D+ QKVCHL+G+ V + + L PRIKVGR++V KAQ +EQA
Sbjct: 351 NIAFKKERNTDQASMPDNTAAQKVCHLMGINVNDFTRGILLPRIKVGRDYVQKAQTKEQA 410
Query: 1273 EFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICIN 1452
+FA+EA+AKA+YER+F+WLV R+NK+LD+T RQGASFIGILDIAGFEIF++NSFEQ+CIN
Sbjct: 411 DFAIEALAKATYERMFRWLVMRVNKALDKTKRQGASFIGILDIAGFEIFELNSFEQLCIN 470
Query: 1453 YTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDE 1623
YTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP IDLIEKP G+LALLDE
Sbjct: 471 YTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDE 530
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMD 1800
EC FPKA DKSFVEK+ + H KF P ++ K+ F+++HYAGRVDY AD+WLMKNMD
Sbjct: 531 ECWFPKATDKSFVEKVVQEQGTHSKFQKPKQLKDKADFSIMHYAGRVDYKADEWLMKNMD 590
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQLH 1968
PLN+N+ L+ S+D FV +WKD + G+ A M +TA ++RKGMFRTV Q +
Sbjct: 591 PLNDNIATLLNQSSDKFVCELWKDVDRIVGLDQVAGMGDTALPGAFKTRKGMFRTVGQFY 650
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
KEQL+KLM TLRNT+P+FVRCIIPNHEKKSGK++++LVL+QLRCNGVLEGIRICRQGFPN
Sbjct: 651 KEQLSKLMATLRNTNPNFVRCIIPNHEKKSGKLDAHLVLDQLRCNGVLEGIRICRQGFPN 710
Query: 2149 RVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAH 2328
RV FQEFR RYEILTP+ IPK F+DGK++ MI AL++D+NLYRIGQSKVFFR GVLAH
Sbjct: 711 RVVFQEFRQRYEILTPNAIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAH 770
Query: 2329 LEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRL 2508
LEEERDLK+T +I++FQA CRG+L+R+ ++ N AYLKLRNWQWWRL
Sbjct: 771 LEEERDLKITDVIISFQACCRGYLARKAFSKRQQQLTAMKVIQRNCAAYLKLRNWQWWRL 830
Query: 2509 FTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQ 2688
FTKVKPLLQ R D+E+ AK+ EL+ KE + E E E + E+ +QEQLQ
Sbjct: 831 FTKVKPLLQANRFDEELLAKEVELQKVKELHVSSEQKMSEMENIQMTLQQEKMQLQEQLQ 890
Query: 2689 QESENSAELDDIRGRLQTRNQELEYIVNDMRDRL 2790
E E AE +++R RL T+ QELE I++D+ R+
Sbjct: 891 AEIELCAEAEEMRARLATKKQELEEILHDLESRV 924
>gi|1408194|gb|AAB03661.1| myosin heavy chain [Placopecten
magellanicus]
Length = 1950
Score = 1171 bits (3030), Expect = 0.0
Identities = 660/1917 (34%), Positives = 1087/1917 (56%), Gaps = 16/1917 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
D QYL V R + T A + +K CWVPD EGF I+ +E+ V++V +
Sbjct: 9 DFQYLAVDRKKMMKEQT-APFDGKKNCWVPDPKEGFASAEIQSSKGEEITVKIVSDNSTR 67
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
T+ +DD+Q+ NPPKF+K+EDM+ +TYLNEASVL+NL+ RY + LIYTYSGLFC+ +NPY+
Sbjct: 68 TVKKDDIQQMNPPKFEKLEDMANMTYLNEASVLNNLRGRYTAGLIYTYSGLFCIAVNPYR 127
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
+LPIY++ +I +++GK++ E+PPH+F++AD AY++M+ +RE+QS L TGESGAGKTE+TK
Sbjct: 128 RLPIYTDSVIAKYRGKRKTEIPPHLFSVADNAYQNMVTDRENQSCLITGESGAGKTESTK 187
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVI Y A VA N Q+ ++P LE Q+++ANP+LEAFGN+KTV+
Sbjct: 188 KVIMYFARVAA-------NLYKQK---EEPVPNLRASNLEDQIIEANPVLEAFGNAKTVR 237
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
N+NSSRFGKFIRI+F +G I+GA+IE YLLEKSRV Q ER++HIFYQI + E
Sbjct: 238 NNNSSRFGKFIRIHFGPTGKIAGADIETYLLEKSRVTYQQSAERNYHIFYQICSN-AIPE 296
Query: 907 KSEYLLEGVDN--YRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAV 1080
+E +L D+ Y F+ +T+ N+DDV+EF + I+GF +E +S+ + +++
Sbjct: 297 LNEVMLITPDSGLYSFINQGCLTVDNIDDVEEFKLCDEAFDILGFTKEEKTSMFKCTASI 356
Query: 1081 LLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQN 1260
L +G ++F Q + +QA +KV L G+ +L KA L+P++KVG E V K QN
Sbjct: 357 LHMGEMKFKQRPREEQAESDGTAEAEKVAFLCGINAGDLLKALLKPKVKVGTEMVTKGQN 416
Query: 1261 QEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQ 1440
+Q +V A++K+ Y+R+F WLV R+N++LD T + +IG+LDIAGFEIFD NSFEQ
Sbjct: 417 LQQVINSVGALSKSLYDRMFNWLVKRVNRTLD-TKAKRNYYIGVLDIAGFEIFDFNSFEQ 475
Query: 1441 ICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLD 1620
+CINYTNE+LQQ FN+ MF+LEQEEY++EGI+W+FIDFG+DLQ IDLIEKPMG+L++L+
Sbjct: 476 LCINYTNERLQQFFNHHMFVLEQEEYKKEGIQWEFIDFGMDLQMCIDLIEKPMGILSILE 535
Query: 1621 EECLFPKANDKSFVEKLQKTH-NKHPKFIVPDMRSK-----SHFAVVHYAGRVDYSADQW 1782
EEC+FPKA+DKSF + + H K+ F P ++ +HF + HYAG V YS W
Sbjct: 536 EECMFPKADDKSFQDYSYQNHIGKNRMFTKPGKPTRPNQGHAHFELHHYAGNVPYSIAGW 595
Query: 1783 LMKNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGM-FRTVS 1959
L KN DP+NENVV L+ S +P VA +++ + E A G + +K F+T+S
Sbjct: 596 LDKNKDPINENVVSLLAVSKEPLVAELFRAPD-------EPAGGAGGKKKKKSSAFQTIS 648
Query: 1960 QLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQG 2139
+H+E L KLM LR T+PHFVRCIIPN EK G +++ LVL QL+CNGVLEGIRICR+G
Sbjct: 649 AVHRESLNKLMCNLRRTNPHFVRCIIPNLEKDPGLVDAELVLHQLQCNGVLEGIRICRKG 708
Query: 2140 FPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGV 2319
FP+R+ + EF+ RY IL P+ IP+ F+DGK K++T L +D + YR+G +KVFF+ GV
Sbjct: 709 FPSRLIYSEFKQRYSILAPNAIPQGFVDGKTVSEKILTGLQMDPSEYRLGTTKVFFKAGV 768
Query: 2320 LAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQW 2499
L +LEE RD +L+ +I FQA RG+L R+ Y N +L LRNWQW
Sbjct: 769 LGNLEEMRDERLSKIISMFQAHIRGYLIRKAYKKLQDQRIGLSVIQRNIRKWLVLRNWQW 828
Query: 2500 WRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQE 2679
W+L+ KVKPLL + R ++E++ + +++ KE L K E +E E++ ++ ++ +
Sbjct: 829 WKLYAKVKPLLSIARLEEEMKEQVEQMDKMKEDLAKTERIKKELEEQNVTLLEQKNDLFL 888
Query: 2680 QLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRD 2859
QLQ ++ + +D +L + + E + ++ +RL ++K +
Sbjct: 889 QLQTIEDSMGDQEDRVEKLIMQKADFESQIKELEERLLDEEDAASDLEGIKKKMEGDNAN 948
Query: 2860 XXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQ 3039
+K + D + +
Sbjct: 949 LKKDIGELEHSLQKSEQEKAHKDNQISTLQGEMSQQDEHIGKLNKEKKALEEANKKTSDS 1008
Query: 3040 LLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEK 3219
L E++ H K K +LE L ELE +L RE++ + ++E+ K K+ +L+ +++++ +
Sbjct: 1009 LQAEEDKCNHLNKLKAKLEQALDELEDNLEREKKVRGDVEKAKSKVEQDLKSTQENVEDL 1068
Query: 3220 MGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNAR 3399
EL + +++ E+ ++ ++E V+ +Q++++++Q I+EL E++E ERNAR
Sbjct: 1069 ERVKRELEENVRRKEAEITTLNSKLEDEQNLVSQLQRKIKELQARIEELEEELEAERNAR 1128
Query: 3400 NKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGK 3576
+K E R E+ +LE++ G+ LD+ AT Q +L +++ E+ +R +E+ E +
Sbjct: 1129 SKVEKQRAELNRELEEL-GERLDEAGGATSAQIELNKKREAELLKIRRDLEEASLQHEAQ 1187
Query: 3577 IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKK 3756
I + K E+ DQ++Q +K +S+ EK+ N+ + E D+ +I + ++ +K
Sbjct: 1188 ISAIRKKHQDAANEMADQVDQLQKVKSKSEKENNKMESENEDLQAQIQHISKNKGCSEKV 1247
Query: 3757 RKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATA 3936
K E+ + ++ A L +S L Q R + E L+R E+ EH + + + +
Sbjct: 1248 MKQFESQVSDLNARLEDSQRSINELQSQKSRLQAENSDLSRQLEDAEHRVSVLSKEKSQL 1307
Query: 3937 XXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGA 4116
TR + N R + + +A ++ EE + ++ +++++ A
Sbjct: 1308 TSQLEDARRSLEDETRARTKLQNEIRNMHADMDAAREQLEEEQESKSDVQRQLSKANNEI 1367
Query: 4117 GEARRKAE-ESVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDS 4287
+ R K E E N ++LE+ ++K L + ++ +E + + ++K ++QQELED
Sbjct: 1368 QQWRSKFESEGANRTEELEDQKRKILGKLSEAEQNMEAANAKASALDKAKSRLQQELEDL 1427
Query: 4288 SMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEV 4467
S+E++ A+ EK+Q+ F+ +E + V + + +E R + + V
Sbjct: 1428 SIEVDRANANVNQMEKKQRAFDKTTSEWQSKVNSLQSELENSQKESRGYSAELYRIKASV 1487
Query: 4468 DIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELE 4647
+ ++ + R ++L E+ D + G++ HEL+KA+R LE E +++ +EE E
Sbjct: 1488 EEYQDSIGSLRRENKNLADEIHDLTDQLSEGGRSSHELDKARRRLEMEKEELQAALEEAE 1547
Query: 4648 DNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGK 4827
L+ E +R ++ +++E D+ I K+ E + RR + + ++ LE E +GK
Sbjct: 1548 GALEQEEAKVMRAQLEIATVRNEIDKRIQEKEEEFDNTRRNHQRALESMQASLEAEAKGK 1607
Query: 4828 SGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIA 5007
+ A+ +KK+E I ELE L+ +NR K E E Q EE ++ +++
Sbjct: 1608 ADALRIKKKLEQDINELEVALDASNRGKAEMEKTVKRYQQQIREMQTSIEEEQRQRDEAR 1667
Query: 5008 ALLREADRKFRAVEAEREQLREANEGLMQARK-QXXXXXXXXXXXRAKGGGISS--EEKR 5178
A+R+ + E E+LR A E +ARK +SS +KR
Sbjct: 1668 ESYNMAERRCTLMSGEVEELRAALEQAERARKGSENELADANDRVNELTSQVSSVQGQKR 1727
Query: 5179 RLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLER 5358
+LE I + A ++ +KA ++ +L E+ + + E +++LE
Sbjct: 1728 KLEGDINAMQTDLDEMHGELKGADERCKKAMADAARLADELRAEQDHSNQVEKVRKNLES 1787
Query: 5359 SNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLN 5538
++++ ++ E E+ + + + LE++V LE +L+ E + + R+ ++RL
Sbjct: 1788 QVKEFQIRLDEAEASSLKGGKKLIQKLESRVHELEAELDNEQRRHAETQKNMRKADRRLK 1847
Query: 5539 DTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+ Q +++++ E+ +EL++K N K + +RQ++EAE+ + K+R Q E ++
Sbjct: 1848 ELAFQADEDRKNQERLQELIDKLNAKIKTFKRQVEEAEEIAAINLAKYRKAQHELEE 1904
Score = 192 bits (488), Expect = 8e-47
Identities = 182/913 (19%), Positives = 403/913 (43%), Gaps = 35/913 (3%)
Frame = +1
Query: 3100 QLHELEQDLNRERQYKSELEQHKRKLLAELED---SKDHLAEKMGKVEELNNQLMKRDEE 3270
Q+ ++++DL + + K ELE+ LL + D + + MG E+ +L+ + +
Sbjct: 854 QMDKMKEDLAKTERIKKELEEQNVTLLEQKNDLFLQLQTIEDSMGDQEDRVEKLIMQKAD 913
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ Q+ +E L+ ++ D + ++ +++ ME + NA K ++ E+ L+K
Sbjct: 914 FESQIKELEER-----LLDEE--DAASDLEGIKKKMEGD-NANLKKDI--GELEHSLQKS 963
Query: 3451 KGDVLDKVDEATMLQDLMSRKDEEV---NATKRAIEQIQHTMEGKIEEQ----------K 3591
+ + K ++ + LQ MS++DE + N K+A+E+ ++ + K
Sbjct: 964 EQEKAHKDNQISTLQGEMSQQDEHIGKLNKEKKALEEANKKTSDSLQAEEDKCNHLNKLK 1023
Query: 3592 AKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHE 3771
AK + ++EL D +E+ KK R +EK +++ +Q+ + + L+ + ++++ + E
Sbjct: 1024 AKLEQALDELEDNLEREKKVRGDVEKAKSKVEQDLKSTQENVEDLERVKRELEENVRRKE 1083
Query: 3772 AHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXX 3951
A + + + L E ++ L+ QL+R EL R+ E EE A R
Sbjct: 1084 AEITTLNSKL----EDEQNLVSQLQRKIKELQ--ARIEELEEELEAERNARSKVEKQRAE 1137
Query: 3952 XXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARR 4131
RL A + Q+E L++K EAE L+ RR
Sbjct: 1138 LNRELEELGERLDEAGGATSAQIE------LNKKREAELLK----------------IRR 1175
Query: 4132 KAEESVNQ---QLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
EE+ Q Q+ +RKK+ + Q+++ + K + + K++ E ED +++
Sbjct: 1176 DLEEASLQHEAQISAIRKKHQDAANEMADQVDQLQKVKSKSEKENNKMESENEDLQAQIQ 1235
Query: 4303 NVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKE 4482
++ + SEK K+FESQ+++ + L D EL+ +++R L E +
Sbjct: 1236 HISKNKGCSEKVMKQFESQVSD----LNARLEDSQRSINELQSQKSR---LQAENSDLSR 1288
Query: 4483 HLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQM----EELED 4650
LE+++ L +E S +D +++ + +A+ L+ E+ +M M E+LE+
Sbjct: 1289 QLEDAEHRVSVLSKEKSQLTSQLEDARRSLEDETRARTKLQNEIRNMHADMDAAREQLEE 1348
Query: 4651 NLQIAEDARLRLEVTN---QALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKR 4821
+ D + +L N Q +S+ + +N+ E E+++R +L ++ + E +E
Sbjct: 1349 EQESKSDVQRQLSKANNEIQQWRSKFESEGANRTEELEDQKRKILGKLSEAEQNMEAANA 1408
Query: 4822 GKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKED 5001
S + +++ ++ +L +++ AN + E+Q + + E+
Sbjct: 1409 KASALDKAKSRLQQELEDLSIEVDRANANVNQMEKKQRAFDKTTSEWQSKVNSLQSELEN 1468
Query: 5002 IAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSE---E 5172
R + ++A E+ +++ L + K ++GG S E
Sbjct: 1469 SQKESRGYSAELYRIKASVEEYQDSIGSLRRENKNLADEIHDLTDQLSEGGRSSHELDKA 1528
Query: 5173 KRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSL 5352
+RRLE + + + E K +AQ+++ + + ++++ + +++
Sbjct: 1529 RRRLEMEKEELQAALEEAEGALEQEEAKVMRAQLEIATVRNE------IDKRIQEKEEEF 1582
Query: 5353 ERSNRDYKAKITELESGAQSRARAQMAALEAK------VQYLEDQLNVEGQEKTAANRAA 5514
+ + R+++ + +++ ++ A+ + AL K + LE L+ + K +
Sbjct: 1583 DNTRRNHQRALESMQASLEAEAKGKADALRIKKKLEQDINELEVALDASNRGKAEMEKTV 1642
Query: 5515 RRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQ 5694
+R ++++ + E+E+R ++A+ E N+ R E E+ + R +
Sbjct: 1643 KRYQQQIREMQTSIEEEQRQRDEAR---ESYNMAERRCTLMSGEVEELRAALEQAERARK 1699
Query: 5695 READDLLDANEQL 5733
++L DAN+++
Sbjct: 1700 GSENELADANDRV 1712
Score = 180 bits (457), Expect = 3e-43
Identities = 184/939 (19%), Positives = 386/939 (40%), Gaps = 12/939 (1%)
Frame = +1
Query: 2569 DDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRN 2748
+ +L++T+E + +E RE E+ + + E + +L+ E ++L LQ R
Sbjct: 1055 EQDLKSTQENVEDLERVKRELEENVRRKEAEITTLNSKLEDEQNLVSQLQRKIKELQARI 1114
Query: 2749 QELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVD 2928
+ELE + R+ S + E + + + +
Sbjct: 1115 EELEEELEAERNARSKVEKQRAELNRELEELGERLDEAGGATSAQIELNKKREAELLKIR 1174
Query: 2929 QXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLH 3108
+ ++A ++ D ++ + VK+K EN
Sbjct: 1175 RDL----------EEASLQHEAQISAIRKKHQDAANEMADQVDQLQK-VKSKSEKENNKM 1223
Query: 3109 ELE-QDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQ- 3282
E E +DL + Q+ S+ + K++ + E L ++ + N+L + LQ +
Sbjct: 1224 ESENEDLQAQIQHISKNKGCSEKVMKQFESQVSDLNARLEDSQRSINELQSQKSRLQAEN 1283
Query: 3283 --LTRYDEESAN-VTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVK 3453
L+R E++ + V+++ K+ + + +++ R +E E AR K + R + A ++ +
Sbjct: 1284 SDLSRQLEDAEHRVSVLSKEKSQLTSQLEDARRSLEDETRARTKLQNEIRNMHADMDAAR 1343
Query: 3454 GDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQI 3633
+ ++ + + +Q +S+ + E+ + E ++E+QK K ++ E +
Sbjct: 1344 EQLEEEQESKSDVQRQLSKANNEIQQWRSKFESEGANRTEELEDQKRKILGKLSEAEQNM 1403
Query: 3634 EQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESD 3813
E + S L+K +++ QE D++ E+ A+ ++KK++ + E Q+ + +
Sbjct: 1404 EAANAKASALDKAKSRLQQELEDLSIEVDRANANVNQMEKKQRAFDKTTSEWQSKV---N 1460
Query: 3814 EHKRTLIDQLERSRDELDHLNRVR---EEEEHAFANMQRRLATAXXXXXXXXXXXXXXTR 3984
+ L + + SR L R++ EE + + +++R R
Sbjct: 1461 SLQSELENSQKESRGYSAELYRIKASVEEYQDSIGSLRRENKNLADEIHDLTDQLSEGGR 1520
Query: 3985 LKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLE 4164
R+LE EK L EEAEG E ++ A+ R + ++ + ++ E
Sbjct: 1521 SSHELDKARRRLEMEKEELQAALEEAEGALEQEEAKVMRAQLEIATVRNEIDKRIQEKEE 1580
Query: 4165 EL---RKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEK 4335
E R+ + R +E +Q LE K L+ KKK++Q++ + + L+ + EK
Sbjct: 1581 EFDNTRRNHQRALESMQASLEAEAKGKADALRIKKKLEQDINELEVALDASNRGKAEMEK 1640
Query: 4336 RQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRS 4515
K+++ Q+ E + ++++ RD + E R + EV+ ++ LE+++R R+
Sbjct: 1641 TVKRYQQQIREMQTSIEEEQRQRDEARESYNMAERRCTLMSGEVEELRAALEQAERARKG 1700
Query: 4516 LQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVT 4695
+ EL D+ ++ V ++ KR LE ++N M+ ++E+ L+ A D R + +
Sbjct: 1701 SENELADANDRVNELTSQVSSVQGQKRKLEGDINAMQTDLDEMHGELKGA-DERCKKAMA 1759
Query: 4696 NQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENEL-ENEKRGKSGAVSHRKKIENQIG 4872
+ A ++ RA + + E+ R+ L Q+++ + L E E G +K+E+++
Sbjct: 1760 DAARLADELRAEQDHSNQVEKVRKNLESQVKEFQIRLDEAEASSLKGGKKLIQKLESRVH 1819
Query: 4873 ELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEA 5052
ELE +L+ R E +R+ADR+ + +
Sbjct: 1820 ELEAELDNEQRRHAETQKN----------------------------MRKADRRLKELAF 1851
Query: 5053 EREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQS 5232
+ ++ R+ E L + +L AKI +
Sbjct: 1852 QADEDRKNQERLQELID-------------------------KLNAKIKTFKRQVEEAEE 1886
Query: 5233 NCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQS 5349
+ + K RKAQ +LE+ + QK A+ +S
Sbjct: 1887 IAAINLAKYRKAQHELEEAEERADTADSSLQKFRAKSRS 1925
Score = 178 bits (451), Expect = 2e-42
Identities = 156/746 (20%), Positives = 317/746 (41%), Gaps = 22/746 (2%)
Frame = +1
Query: 3028 LTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDH 3207
L +L D + K RL+ + +L + L S L + K +L ++LED++
Sbjct: 1258 LNARLEDSQRSINELQSQKSRLQAENSDLSRQLEDAEHRVSVLSKEKSQLTSQLEDARRS 1317
Query: 3208 LAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETE 3387
L ++ +L N++ ++ + +EE + + +Q+Q+ I + R E+E
Sbjct: 1318 LEDETRARTKLQNEIRNMHADMDAAREQLEEEQESKSDVQRQLSKANNEIQQWRSKFESE 1377
Query: 3388 RNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTM 3567
N+ E +LE K +L K+ EA + E NA A
Sbjct: 1378 --GANRTE--------ELEDQKRKILGKLSEA-------EQNMEAANAKASA-------- 1412
Query: 3568 EGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADI 3747
+++ K++ +++E+L ++++ +Q+EK+Q D+ ++ ++ LQ+ +
Sbjct: 1413 ---LDKAKSRLQQELEDLSIEVDRANANVNQMEKKQRAFDKTTSEWQSKVNSLQSELENS 1469
Query: 3748 DKKRKIHEAHLMEIQANLAESDE-------HKRTLIDQLERSRDELDHLNRVREEEEHAF 3906
K+ + + A L I+A++ E + + L D++ D+L R E + A
Sbjct: 1470 QKESRGYSAELYRIKASVEEYQDSIGSLRRENKNLADEIHDLTDQLSEGGRSSHELDKA- 1528
Query: 3907 ANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLE 4086
R+LE EK L EEAEG E
Sbjct: 1529 ----------------------------------RRRLEMEKEELQAALEEAEGALEQEE 1554
Query: 4087 KEIHAARQGAGEARRKAEESVNQQLEEL---RKKNLRDVEHLQKQLEESEVAKERILQSK 4257
++ A+ R + ++ + ++ EE R+ + R +E +Q LE K L+ K
Sbjct: 1555 AKVMRAQLEIATVRNEIDKRIQEKEEEFDNTRRNHQRALESMQASLEAEAKGKADALRIK 1614
Query: 4258 KKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRE 4437
KK++Q++ + + L+ + EK K+++ Q+ E + ++++ RD + E
Sbjct: 1615 KKLEQDINELEVALDASNRGKAEMEKTVKRYQQQIREMQTSIEEEQRQRDEARESYNMAE 1674
Query: 4438 TRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELN 4617
R + EV+ ++ LE+++R R+ + EL D+ ++ V ++ KR LE ++N
Sbjct: 1675 RRCTLMSGEVEELRAALEQAERARKGSENELADANDRVNELTSQVSSVQGQKRKLEGDIN 1734
Query: 4618 DMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLE 4797
M+ ++E+ L+ A D R + + + A ++ RA + + E+ R+ L Q+++ +
Sbjct: 1735 AMQTDLDEMHGELKGA-DERCKKAMADAARLADELRAEQDHSNQVEKVRKNLESQVKEFQ 1793
Query: 4798 NEL-ENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIEC 4974
L E E G +K+E+++ ELE +L+ R E E +
Sbjct: 1794 IRLDEAEASSLKGGKKLIQKLESRVHELEAELDNEQRRHAETQKNMRKADRRLKELAFQA 1853
Query: 4975 EEARQAKEDIAALLREADRKFRAVEAEREQ-----------LREANEGLMQARKQXXXXX 5121
+E R+ +E + L+ + + K + + + E+ R+A L +A ++
Sbjct: 1854 DEDRKNQERLQELIDKLNAKIKTFKRQVEEAEEIAAINLAKYRKAQHELEEAEERADTAD 1913
Query: 5122 XXXXXXRAKGGGISSEEKRRLEAKIA 5199
RAK S ++ + A
Sbjct: 1914 SSLQKFRAKSRSSVSVQRSSVSVSAA 1939
Score = 87.8 bits (216), Expect = 3e-15
Identities = 121/631 (19%), Positives = 260/631 (41%), Gaps = 61/631 (9%)
Frame = +1
Query: 4042 LDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEE 4221
+D K +E + L+ + R G + KA V LEE+R + L + + +
Sbjct: 735 VDGKTVSEKILTGLQMDPSEYRLGTTKVFFKA--GVLGNLEEMRDERLSKII----SMFQ 788
Query: 4222 SEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLD 4401
+ + I ++ KK+Q + S+ N+R + + + A K LL
Sbjct: 789 AHIRGYLIRKAYKKLQDQRIGLSVIQRNIR--------KWLVLRNWQWWKLYAKVKPLLS 840
Query: 4402 RDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHEL 4581
+ +E++++ + ++D MKE L +++R+++ L+++ + K+D + +
Sbjct: 841 IARLEEEMKEQ-------VEQMDKMKEDLAKTERIKKELEEQNVTLLEQKNDLFLQLQTI 893
Query: 4582 EKAKRSLEAELN-------DMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNK 4740
E + E + D Q++ELE+ L EDA LE + K E D A K
Sbjct: 894 EDSMGDQEDRVEKLIMQKADFESQIKELEERLLDEEDAASDLEGIKK--KMEGDNANLKK 951
Query: 4741 DV--------EAEEKRRGLLKQIRDLENELENE-------KRGKSGAVSHRKKIENQIGE 4875
D+ ++E+++ QI L+ E+ + + K KK + +
Sbjct: 952 DIGELEHSLQKSEQEKAHKDNQISTLQGEMSQQDEHIGKLNKEKKALEEANKKTSDSLQA 1011
Query: 4876 LEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAE 5055
E + N+LK + E + E ++ + D+ + ++ ++ +
Sbjct: 1012 EEDKCNHLNKLKAK-------LEQALDELEDNLEREKKVRGDVEKAKSKVEQDLKSTQEN 1064
Query: 5056 REQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRR---LEAKIAQXXXXXXXX 5226
E L L + ++ + S+ +R+ L+A+I +
Sbjct: 1065 VEDLERVKRELEENVRRKEAEITTLNSKLEDEQNLVSQLQRKIKELQARI-EELEEELEA 1123
Query: 5227 QSNCELAIDKQR-KAQVQLEQITTDL-------SMERTLNQKTEAE----KQSLERSNRD 5370
+ N ++KQR + +LE++ L S + LN+K EAE ++ LE ++
Sbjct: 1124 ERNARSKVEKQRAELNRELEELGERLDEAGGATSAQIELNKKREAELLKIRRDLEEASLQ 1183
Query: 5371 YKAKITELESGAQ-----------------SRARAQMAALEAKVQYLEDQLNVEGQEKTA 5499
++A+I+ + Q S++ + +E++ + L+ Q+ + K
Sbjct: 1184 HEAQISAIRKKHQDAANEMADQVDQLQKVKSKSEKENNKMESENEDLQAQIQHISKNKGC 1243
Query: 5500 ANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAE-------DE 5658
+ + ++ E +++D + ED +R+ + + + +N +L RQL++AE E
Sbjct: 1244 SEKVMKQFESQVSDLNARLEDSQRSINELQSQKSRLQAENSDLSRQLEDAEHRVSVLSKE 1303
Query: 5659 MSRERTKHRNVQREADDLLDANEQLTRELMN 5751
S+ ++ + +R +D A +L E+ N
Sbjct: 1304 KSQLTSQLEDARRSLEDETRARTKLQNEIRN 1334
>gi|1408192|gb|AAB03660.1| myosin heavy chain [Placopecten
magellanicus]
Length = 1941
Score = 1170 bits (3028), Expect = 0.0
Identities = 660/1917 (34%), Positives = 1088/1917 (56%), Gaps = 16/1917 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
D QYL V R + T A + +K CWVPD EGF I+ +E+ V++V +
Sbjct: 9 DFQYLAVDRKKMMKEQT-APFDGKKNCWVPDPKEGFASAEIQSSKGEEITVKIVSDNSTR 67
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
T+ +DD+Q+ NPPKF+K+EDM+ +TYLNEASVL+NL+ RY + LIYTYSGLFC+ +NPY+
Sbjct: 68 TVKKDDIQQMNPPKFEKLEDMANMTYLNEASVLNNLRGRYTAGLIYTYSGLFCIAVNPYR 127
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
+LPIY++ +I +++GK++ E+PPH+F++AD AY++M+ +RE+QS L TGESGAGKTENTK
Sbjct: 128 RLPIYTDSVIAKYRGKRKTEIPPHLFSVADNAYQNMVTDRENQSCLITGESGAGKTENTK 187
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVI YLA VA A + K+ + ++ QK G LE Q++QANP+LEA+GN+KT +
Sbjct: 188 KVIMYLAKVACAVKKKT---SEEEEADQKK------GSLEDQIIQANPVLEAYGNAKTTR 238
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
N+NSSRFGKFIRI+F +G I+GA+IE YLLEKSRV Q ER++HIFYQI + E
Sbjct: 239 NNNSSRFGKFIRIHFGPTGKIAGADIETYLLEKSRVTYQQSAERNYHIFYQICSN-AIPE 297
Query: 907 KSEYLLEGVDN--YRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAV 1080
+E +L D+ Y F+ +T+ N+DDV+EF + I+GF +E +S+ + +++
Sbjct: 298 LNEVMLITPDSGLYSFINQGCLTVDNIDDVEEFKLCDEAFDILGFTKEEKTSMFKCTASI 357
Query: 1081 LLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQN 1260
L +G ++F Q + +QA +KV L G+ +L KA L+P++KVG E V K QN
Sbjct: 358 LHMGEMKFKQRPREEQAESDGTAEAEKVAFLCGINAGDLLKALLKPKVKVGTEMVTKGQN 417
Query: 1261 QEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQ 1440
+Q +V A++K+ Y+R+F WLV R+N++LD T + +IG+LDIAGFEIFD NSFEQ
Sbjct: 418 LQQVINSVGALSKSLYDRMFNWLVKRVNRTLD-TKAKRNYYIGVLDIAGFEIFDFNSFEQ 476
Query: 1441 ICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLD 1620
+CINYTNE+LQQ FN+ MF+LEQEEY++EGI+W+FIDFG+DLQ IDLIEKPMG+L++L+
Sbjct: 477 LCINYTNERLQQFFNHHMFVLEQEEYKKEGIQWEFIDFGMDLQMCIDLIEKPMGILSILE 536
Query: 1621 EECLFPKANDKSFVEKLQKTH-NKHPKFIVPDMRSK-----SHFAVVHYAGRVDYSADQW 1782
EEC+FPKA+DKSF + + H K+ F P ++ +HF + HYAG V YS W
Sbjct: 537 EECMFPKADDKSFQDYSYQNHIGKNRMFTKPGKPTRPNQGHAHFELHHYAGNVPYSIAGW 596
Query: 1783 LMKNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGM-FRTVS 1959
L KN DP+NENVV L+ S +P VA +++ + E A G + +K F+T+S
Sbjct: 597 LDKNKDPINENVVSLLAVSKEPLVAELFRAPD-------EPAGGAGGKKKKKSSAFQTIS 649
Query: 1960 QLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQG 2139
+H+E L KLM L +T PHFVRCIIPN K+ G +++ LVL QL+CNGVLEGIRICR+G
Sbjct: 650 AVHRESLNKLMKNLYSTHPHFVRCIIPNELKQPGLVDAELVLHQLQCNGVLEGIRICRKG 709
Query: 2140 FPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGV 2319
FP+R+ + EF+ RY IL P+ IP+ F+DGK K++T L +D + YR+G +KVFF+ GV
Sbjct: 710 FPSRLIYSEFKQRYSILAPNAIPQGFVDGKTVSEKILTGLQMDPSEYRLGTTKVFFKAGV 769
Query: 2320 LAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQW 2499
L +LEE RD +L+ +I FQA RG+L R+ Y N +L LRNWQW
Sbjct: 770 LGNLEEMRDERLSKIISMFQAHIRGYLIRKAYKKLQDQRIGLSVIQRNIRKWLVLRNWQW 829
Query: 2500 WRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQE 2679
W+L+ KVKPLL + R ++E++ + +++ KE L K E +E E++ ++ ++ +
Sbjct: 830 WKLYAKVKPLLSIARLEEEMKEQVEQMDKMKEDLAKTERIKKELEEQNVTLLEQKNDLFL 889
Query: 2680 QLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRD 2859
QLQ ++ + +D +L + + E + ++ +RL ++K +
Sbjct: 890 QLQTIEDSMGDQEDRVEKLIMQKADFESQIKELEERLLDEEDAASDLEGIKKKMEGDNAN 949
Query: 2860 XXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQ 3039
+K + D + +
Sbjct: 950 LKKDIGELEHSLQKSEQEKAHKDNQISTLQGEMSQQDEHIGKLNKEKKALEEANKKTSDS 1009
Query: 3040 LLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEK 3219
L E++ H K K +LE L ELE +L RE++ + ++E+ K K+ +L+ +++++ +
Sbjct: 1010 LQAEEDKCNHLNKLKAKLEQALDELEDNLEREKKVRGDVEKAKSKVEQDLKSTQENVEDL 1069
Query: 3220 MGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNAR 3399
EL + +++ E+ ++ ++E V+ +Q++++++Q I+EL E++E ERNAR
Sbjct: 1070 ERVKRELEENVRRKEAEITTLNSKLEDEQNLVSQLQRKIKELQARIEELEEELEAERNAR 1129
Query: 3400 NKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGK 3576
+K E R E+ +LE++ G+ LD+ AT Q +L +++ E+ +R +E+ E +
Sbjct: 1130 SKVEKQRAELNRELEEL-GERLDEAGGATSAQIELNKKREAELLKIRRDLEEASLQHEAQ 1188
Query: 3577 IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKK 3756
I + K E+ DQ++Q +K +S+LEK + +E D+ ++ ++ +K
Sbjct: 1189 ISAIRKKHQDAANEMADQVDQLQKVKSKLEKDKKDLKREMDDLESQMTHDMKNKGCSEKV 1248
Query: 3757 RKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATA 3936
K E+ + ++ A L +S L Q R + E L+R E+ EH + + + +
Sbjct: 1249 MKQFESQVSDLNARLEDSQRSINELQSQKSRLQAENSDLSRQLEDAEHRVSVLSKEKSQL 1308
Query: 3937 XXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGA 4116
TR + N R + + +A ++ EE + ++ +++++ A
Sbjct: 1309 TSQLEDARRSLEDETRARTKLQNEIRNMHADMDAAREQLEEEQESKSDVQRQLSKANNEI 1368
Query: 4117 GEARRKAE-ESVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDS 4287
+ R K E E N ++LE+ ++K L + ++ +E + + ++K ++QQELED
Sbjct: 1369 QQWRSKFESEGANRTEELEDQKRKILGKLSEAEQNMEAANAKASALDKAKSRLQQELEDL 1428
Query: 4288 SMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEV 4467
S+E++ A+ EK+Q+ F+ +E + V + + +E R + + V
Sbjct: 1429 SIEVDRANANVNQMEKKQRAFDKTTSEWQSKVNSLQSELENSQKESRGYSAELYRIKASV 1488
Query: 4468 DIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELE 4647
+ ++ + R ++L E+ D + G++ HEL+KA+R LE E +++ +EE E
Sbjct: 1489 EEYQDSIGSLRRENKNLADEIHDLTDQLSEGGRSSHELDKARRRLEMEKEELQAALEEAE 1548
Query: 4648 DNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGK 4827
L+ E +R ++ +++E D+ I K+ E + RR + + ++ LE E +GK
Sbjct: 1549 GALEQEEAKVMRAQLEIATVRNEIDKRIQEKEEEFDNTRRNHQRALESMQASLEAEAKGK 1608
Query: 4828 SGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIA 5007
+ A+ +KK+E I ELE L+ +NR K E E Q EE ++ +++
Sbjct: 1609 ADALRIKKKLEQDINELEVALDASNRGKAEMEKTVKRYQQQIREMQTSIEEEQRQRDEAR 1668
Query: 5008 ALLREADRKFRAVEAEREQLREANEGLMQARK-QXXXXXXXXXXXRAKGGGISS--EEKR 5178
A+R+ + E E+LR A E +ARK +SS +KR
Sbjct: 1669 ESYNMAERRCTLMSGEVEELRAALEQAERARKGSENELADANDRVNELTSQVSSVQGQKR 1728
Query: 5179 RLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLER 5358
+LE I + A ++ +KA ++ +L E+ + + E +++LE
Sbjct: 1729 KLEGDINAMQTDLDEMHGELKGADERCKKAMADAARLADELRAEQDHSNQVEKVRKNLES 1788
Query: 5359 SNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLN 5538
++++ ++ E E+ + + + LE++V LE +L+ E + + R+ ++RL
Sbjct: 1789 QVKEFQIRLDEAEASSLKGGKKLIQKLESRVHELEAELDNEQRRHAETQKNMRKADRRLK 1848
Query: 5539 DTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+ Q +++++ E+ +EL++K N K + +RQ++EAE+ + K+R Q E ++
Sbjct: 1849 ELAFQADEDRKNQERLQELIDKLNAKIKTFKRQVEEAEEIAAINLAKYRKAQHELEE 1905
Score = 193 bits (490), Expect = 5e-47
Identities = 182/913 (19%), Positives = 405/913 (43%), Gaps = 35/913 (3%)
Frame = +1
Query: 3100 QLHELEQDLNRERQYKSELEQHKRKLLAELED---SKDHLAEKMGKVEELNNQLMKRDEE 3270
Q+ ++++DL + + K ELE+ LL + D + + MG E+ +L+ + +
Sbjct: 855 QMDKMKEDLAKTERIKKELEEQNVTLLEQKNDLFLQLQTIEDSMGDQEDRVEKLIMQKAD 914
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ Q+ +E L+ ++ D + ++ +++ ME + NA K ++ E+ L+K
Sbjct: 915 FESQIKELEER-----LLDEE--DAASDLEGIKKKMEGD-NANLKKDI--GELEHSLQKS 964
Query: 3451 KGDVLDKVDEATMLQDLMSRKDEEV---NATKRAIEQIQHTMEGKIEEQ----------K 3591
+ + K ++ + LQ MS++DE + N K+A+E+ ++ + K
Sbjct: 965 EQEKAHKDNQISTLQGEMSQQDEHIGKLNKEKKALEEANKKTSDSLQAEEDKCNHLNKLK 1024
Query: 3592 AKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHE 3771
AK + ++EL D +E+ KK R +EK +++ +Q+ + + L+ + ++++ + E
Sbjct: 1025 AKLEQALDELEDNLEREKKVRGDVEKAKSKVEQDLKSTQENVEDLERVKRELEENVRRKE 1084
Query: 3772 AHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXX 3951
A + + + L E ++ L+ QL+R EL R+ E EE A R
Sbjct: 1085 AEITTLNSKL----EDEQNLVSQLQRKIKELQ--ARIEELEEELEAERNARSKVEKQRAE 1138
Query: 3952 XXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARR 4131
RL A + Q+E L++K EAE L+ RR
Sbjct: 1139 LNRELEELGERLDEAGGATSAQIE------LNKKREAELLK----------------IRR 1176
Query: 4132 KAEESVNQ---QLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
EE+ Q Q+ +RKK+ + Q+++ + K ++ + KK +++E++D ++
Sbjct: 1177 DLEEASLQHEAQISAIRKKHQDAANEMADQVDQLQKVKSKLEKDKKDLKREMDDLESQMT 1236
Query: 4303 NVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKE 4482
+ + SEK K+FESQ+++ + L D EL+ +++R L E +
Sbjct: 1237 HDMKNKGCSEKVMKQFESQVSD----LNARLEDSQRSINELQSQKSR---LQAENSDLSR 1289
Query: 4483 HLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQM----EELED 4650
LE+++ L +E S +D +++ + +A+ L+ E+ +M M E+LE+
Sbjct: 1290 QLEDAEHRVSVLSKEKSQLTSQLEDARRSLEDETRARTKLQNEIRNMHADMDAAREQLEE 1349
Query: 4651 NLQIAEDARLRLEVTN---QALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKR 4821
+ D + +L N Q +S+ + +N+ E E+++R +L ++ + E +E
Sbjct: 1350 EQESKSDVQRQLSKANNEIQQWRSKFESEGANRTEELEDQKRKILGKLSEAEQNMEAANA 1409
Query: 4822 GKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKED 5001
S + +++ ++ +L +++ AN + E+Q + + E+
Sbjct: 1410 KASALDKAKSRLQQELEDLSIEVDRANANVNQMEKKQRAFDKTTSEWQSKVNSLQSELEN 1469
Query: 5002 IAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSE---E 5172
R + ++A E+ +++ L + K ++GG S E
Sbjct: 1470 SQKESRGYSAELYRIKASVEEYQDSIGSLRRENKNLADEIHDLTDQLSEGGRSSHELDKA 1529
Query: 5173 KRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSL 5352
+RRLE + + + E K +AQ+++ + + ++++ + +++
Sbjct: 1530 RRRLEMEKEELQAALEEAEGALEQEEAKVMRAQLEIATVRNE------IDKRIQEKEEEF 1583
Query: 5353 ERSNRDYKAKITELESGAQSRARAQMAALEAK------VQYLEDQLNVEGQEKTAANRAA 5514
+ + R+++ + +++ ++ A+ + AL K + LE L+ + K +
Sbjct: 1584 DNTRRNHQRALESMQASLEAEAKGKADALRIKKKLEQDINELEVALDASNRGKAEMEKTV 1643
Query: 5515 RRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQ 5694
+R ++++ + E+E+R ++A+ E N+ R E E+ + R +
Sbjct: 1644 KRYQQQIREMQTSIEEEQRQRDEAR---ESYNMAERRCTLMSGEVEELRAALEQAERARK 1700
Query: 5695 READDLLDANEQL 5733
++L DAN+++
Sbjct: 1701 GSENELADANDRV 1713
Score = 182 bits (463), Expect = 7e-44
Identities = 185/979 (18%), Positives = 400/979 (39%), Gaps = 43/979 (4%)
Frame = +1
Query: 2542 RTDDEIRAKDDE------LRATKERLLKMEHDFRENEKKL-DQVIVERAVIQEQLQQESE 2700
+T D ++A++D+ L+A E+ L D E EKK+ V ++ +++ L+ E
Sbjct: 1005 KTSDSLQAEEDKCNHLNKLKAKLEQALDELEDNLEREKKVRGDVEKAKSKVEQDLKSTQE 1064
Query: 2701 NSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXX 2880
N +L+ ++ L+ + E + + +L ++ + +
Sbjct: 1065 NVEDLERVKRELEENVRRKEAEITTLNSKLEDEQNLVSQLQRKIKELQARIEELEEELEA 1124
Query: 2881 XXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEER 3060
+ +++ A + L + +
Sbjct: 1125 ERNARSKVEKQRAELNRELEELGERLDEAGGATSAQIELNKKREAELLKIRRDLEEASLQ 1184
Query: 3061 AKHGVKA-KGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKM----- 3222
+ + A + + ++ +E+ +++ ++ KS+LE+ K+ L E++D + + M
Sbjct: 1185 HEAQISAIRKKHQDAANEMADQVDQLQKVKSKLEKDKKDLKREMDDLESQMTHDMKNKGC 1244
Query: 3223 ---------GKVEELNNQL---MKRDEELQHQLTRYDEESAN-----------VTLMQKQ 3333
+V +LN +L + ELQ Q +R E+++ V+++ K+
Sbjct: 1245 SEKVMKQFESQVSDLNARLEDSQRSINELQSQKSRLQAENSDLSRQLEDAEHRVSVLSKE 1304
Query: 3334 MRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRK 3513
+ + +++ R +E E AR K + R + A ++ + + ++ + + +Q +S+
Sbjct: 1305 KSQLTSQLEDARRSLEDETRARTKLQNEIRNMHADMDAAREQLEEEQESKSDVQRQLSKA 1364
Query: 3514 DEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQE 3693
+ E+ + E ++E+QK K ++ E +E + S L+K +++ QE
Sbjct: 1365 NNEIQQWRSKFESEGANRTEELEDQKRKILGKLSEAEQNMEAANAKASALDKAKSRLQQE 1424
Query: 3694 RADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHL 3873
D++ E+ A+ ++KK++ + E Q+ + + + L + + SR L
Sbjct: 1425 LEDLSIEVDRANANVNQMEKKQRAFDKTTSEWQSKV---NSLQSELENSQKESRGYSAEL 1481
Query: 3874 NRVR---EEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALL 4044
R++ EE + + +++R R R+LE EK L
Sbjct: 1482 YRIKASVEEYQDSIGSLRRENKNLADEIHDLTDQLSEGGRSSHELDKARRRLEMEKEELQ 1541
Query: 4045 DEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEEL---RKKNLRDVEHLQKQL 4215
EEAEG E ++ A+ R + ++ + ++ EE R+ + R +E +Q L
Sbjct: 1542 AALEEAEGALEQEEAKVMRAQLEIATVRNEIDKRIQEKEEEFDNTRRNHQRALESMQASL 1601
Query: 4216 EESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKAL 4395
E K L+ KKK++Q++ + + L+ + EK K+++ Q+ E + ++++
Sbjct: 1602 EAEAKGKADALRIKKKLEQDINELEVALDASNRGKAEMEKTVKRYQQQIREMQTSIEEEQ 1661
Query: 4396 LDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVH 4575
RD + E R + EV+ ++ LE+++R R+ + EL D+ ++ V
Sbjct: 1662 RQRDEARESYNMAERRCTLMSGEVEELRAALEQAERARKGSENELADANDRVNELTSQVS 1721
Query: 4576 ELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAE 4755
++ KR LE ++N M+ ++E+ L+ A D R + + + A ++ RA + + E
Sbjct: 1722 SVQGQKRKLEGDINAMQTDLDEMHGELKGA-DERCKKAMADAARLADELRAEQDHSNQVE 1780
Query: 4756 EKRRGLLKQIRDLENEL-ENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXX 4932
+ R+ L Q+++ + L E E G +K+E+++ ELE +L+ R E
Sbjct: 1781 KVRKNLESQVKEFQIRLDEAEASSLKGGKKLIQKLESRVHELEAELDNEQRRHAETQKN- 1839
Query: 4933 XXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXX 5112
+R+ADR+ + + + ++ R+ E L +
Sbjct: 1840 ---------------------------MRKADRRLKELAFQADEDRKNQERLQELID--- 1869
Query: 5113 XXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQIT 5292
+L AKI + + + K RKAQ +LE+
Sbjct: 1870 ----------------------KLNAKIKTFKRQVEEAEEIAAINLAKYRKAQHELEEAE 1907
Query: 5293 TDLSMERTLNQKTEAEKQS 5349
+ QK A+ +S
Sbjct: 1908 ERADTADSSLQKFRAKSRS 1926
Score = 180 bits (456), Expect = 4e-43
Identities = 176/908 (19%), Positives = 364/908 (39%), Gaps = 26/908 (2%)
Frame = +1
Query: 2554 EIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRG- 2730
+++ K EL+A R+ ++E + +V +RA + +L++ E LD+ G
Sbjct: 1103 QLQRKIKELQA---RIEELEEELEAERNARSKVEKQRAELNRELEELGER---LDEAGGA 1156
Query: 2731 ---RLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXX 2901
+++ + ++ RD R+K + +
Sbjct: 1157 TSAQIELNKKREAELLKIRRDLEEASLQHEAQISAIRKKHQDAANEMADQVDQLQKVKSK 1216
Query: 2902 XXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKA 3081
DK ++ + L +L D +
Sbjct: 1217 LEKDKKDLKREMDDLESQMTHDMKNKGCSEKVMKQFESQVSDLNARLEDSQRSINELQSQ 1276
Query: 3082 KGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKR 3261
K RL+ + +L + L S L + K +L ++LED++ L ++ +L N++
Sbjct: 1277 KSRLQAENSDLSRQLEDAEHRVSVLSKEKSQLTSQLEDARRSLEDETRARTKLQNEIRNM 1336
Query: 3262 DEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQL 3441
++ + +EE + + +Q+Q+ I + R E+E N+ E +L
Sbjct: 1337 HADMDAAREQLEEEQESKSDVQRQLSKANNEIQQWRSKFESE--GANRTE--------EL 1386
Query: 3442 EKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEEL 3621
E K +L K+ EA + E NA A +++ K++ +++E+L
Sbjct: 1387 EDQKRKILGKLSEA-------EQNMEAANAKASA-----------LDKAKSRLQQELEDL 1428
Query: 3622 HDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL 3801
++++ +Q+EK+Q D+ ++ ++ LQ+ + K+ + + A L I+A++
Sbjct: 1429 SIEVDRANANVNQMEKKQRAFDKTTSEWQSKVNSLQSELENSQKESRGYSAELYRIKASV 1488
Query: 3802 AESDE-------HKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXX 3960
E + + L D++ D+L R E + A
Sbjct: 1489 EEYQDSIGSLRRENKNLADEIHDLTDQLSEGGRSSHELDKA------------------- 1529
Query: 3961 XXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAE 4140
R+LE EK L EEAEG E ++ A+ R + +
Sbjct: 1530 ----------------RRRLEMEKEELQAALEEAEGALEQEEAKVMRAQLEIATVRNEID 1573
Query: 4141 ESVNQQLEEL---RKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVR 4311
+ + ++ EE R+ + R +E +Q LE K L+ KKK++Q++ + + L+
Sbjct: 1574 KRIQEKEEEFDNTRRNHQRALESMQASLEAEAKGKADALRIKKKLEQDINELEVALDASN 1633
Query: 4312 ASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLE 4491
+ EK K+++ Q+ E + ++++ RD + E R + EV+ ++ LE
Sbjct: 1634 RGKAEMEKTVKRYQQQIREMQTSIEEEQRQRDEARESYNMAERRCTLMSGEVEELRAALE 1693
Query: 4492 ESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAED 4671
+++R R+ + EL D+ ++ V ++ KR LE ++N M+ ++E+ L+ A D
Sbjct: 1694 QAERARKGSENELADANDRVNELTSQVSSVQGQKRKLEGDINAMQTDLDEMHGELKGA-D 1752
Query: 4672 ARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENEL-ENEKRGKSGAVSHR 4848
R + + + A ++ RA + + E+ R+ L Q+++ + L E E G
Sbjct: 1753 ERCKKAMADAARLADELRAEQDHSNQVEKVRKNLESQVKEFQIRLDEAEASSLKGGKKLI 1812
Query: 4849 KKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREAD 5028
+K+E+++ ELE +L+ R E E + +E R+ +E + L+ + +
Sbjct: 1813 QKLESRVHELEAELDNEQRRHAETQKNMRKADRRLKELAFQADEDRKNQERLQELIDKLN 1872
Query: 5029 RKFRAVEAEREQ-----------LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEK 5175
K + + + E+ R+A L +A ++ RAK S ++
Sbjct: 1873 AKIKTFKRQVEEAEEIAAINLAKYRKAQHELEEAEERADTADSSLQKFRAKSRSSVSVQR 1932
Query: 5176 RRLEAKIA 5199
+ A
Sbjct: 1933 SSVSVSAA 1940
>gi|47217964|emb|CAG02247.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 2046
Score = 1170 bits (3026), Expect = 0.0
Identities = 602/1192 (50%), Positives = 819/1192 (68%), Gaps = 39/1192 (3%)
Frame = +1
Query: 61 AAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKI 240
A WA +K+ WVP + EGF S+K E D+VLVEL +++T++++D+QK NPPKF K+
Sbjct: 24 ADWAAKKMVWVPSEREGFEAASMKEEKGDQVLVEL-SNGQKMTVNKEDIQKMNPPKFSKV 82
Query: 241 EDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKR 420
EDM+ LT+LNEASVL NL++RY+SSLIYTYSGLFCVV+NPYK LPIYSE +IE +KGKKR
Sbjct: 83 EDMAALTFLNEASVLQNLRERYFSSLIYTYSGLFCVVVNPYKMLPIYSEKIIEMYKGKKR 142
Query: 421 HEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSL 600
HE+PPHI++I D AYR+M+Q+REDQSILCTGESGAGKTENTKKVIQYLA VA + + K
Sbjct: 143 HEVPPHIYSITDNAYRNMMQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK- 201
Query: 601 NAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMS 780
+A QQ GELE QLLQANPILEAFGN+KT+KNDNSSRFGKFI++NFD++
Sbjct: 202 DANPQQG------ASLAYGELEKQLLQANPILEAFGNAKTIKNDNSSRFGKFIKLNFDVT 255
Query: 781 GYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRFLVNR 960
GYI GANI+ YLLEKSR +RQA ER+FHIFY ++ G + + + LLE +YRFLV
Sbjct: 256 GYIVGANIDTYLLEKSRCIRQANTERAFHIFYYMVAGAKDQMREDLLLENFSSYRFLVAG 315
Query: 961 GITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQ 1140
+ +P +D F T+ +M IMGF ++E +++VVS VL LGN++F +E+ S+QA +
Sbjct: 316 HVEIPGQEDDVLFDETLEAMEIMGFTEEERIGMLKVVSTVLQLGNVKFEKERNSEQATMP 375
Query: 1141 DDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA--EFAVEAIAKASYER 1314
D+ QKVCHL + V + +A L PRIKVGRE V KAQ ++QA +FA+EA+AKA Y+R
Sbjct: 376 DNTAAQKVCHLQSISVTDFTRAILTPRIKVGREVVQKAQTKQQATCDFAIEALAKAMYDR 435
Query: 1315 LFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDI----------------------- 1425
LF+W++ R+NK+ D++ RQ +SF+GILDIAGFEIF++
Sbjct: 436 LFRWILARVNKTFDKSKRQSSSFLGILDIAGFEIFEVRSEQKRGPDRFASRRFHRPSAPQ 495
Query: 1426 -NSFEQICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM- 1599
NSFEQ+CINYTNE+LQQLFN+TMFILEQEEY+REGIEW+FIDFGLDL P I+LIE+P
Sbjct: 496 DNSFEQLCINYTNERLQQLFNHTMFILEQEEYKREGIEWNFIDFGLDLLPCIELIERPNN 555
Query: 1600 --GVLALLDEECLFPKANDKSFVEKLQKTHNKHPKFIVPDM-RSKSHFAVVHYAGRVDYS 1770
G+LALLDEEC FPKA D SFVEKL TH H KF P + K F+++HYAG+VDY+
Sbjct: 556 PPGILALLDEECWFPKATDVSFVEKLLNTHTGHVKFSKPKQHKDKLMFSILHYAGKVDYN 615
Query: 1771 ADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAFGMRSRKGM 1944
A WL KNMDPLN+NV L+ NS+ F+ +WKDA+ G+ +M+E++ +S+KGM
Sbjct: 616 AADWLTKNMDPLNDNVTALLNNSSSAFIQDLWKDADRVVGLETMTKMSESSGPTKSKKGM 675
Query: 1945 FRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIR 2124
FRTV QL+KE L+KLMTTL NT P+FVRCIIPNHEK++GK+++NLVLEQLRCNGVLEGIR
Sbjct: 676 FRTVGQLYKESLSKLMTTLNNTQPNFVRCIIPNHEKRAGKMDANLVLEQLRCNGVLEGIR 735
Query: 2125 ICRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVF 2304
ICRQGFPNR+PFQEFR RYEIL IPK F+DGK++ MI L++D NLYRIGQSK+F
Sbjct: 736 ICRQGFPNRIPFQEFRQRYEILAAHAIPKGFMDGKQACCLMIKHLELDPNLYRIGQSKMF 795
Query: 2305 FRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKL 2484
FRTGVLA LEEERDLKLT +I+ FQAQ RGFL+R+ ++ N YLKL
Sbjct: 796 FRTGVLAQLEEERDLKLTVVIIAFQAQARGFLARKAFSKRQQQLSAMKVIQRNCACYLKL 855
Query: 2485 RNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVER 2664
+NWQWWRLFTKVKPLLQVTR ++E+ K++EL+A K+ +K E + ++ +K Q++ ER
Sbjct: 856 KNWQWWRLFTKVKPLLQVTRQEEEMTQKEEELKAAKDLAVKAEAELKDISQKHSQLLEER 915
Query: 2665 AVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQM 2844
++ +LQ E++ AE +++R RL+ + QELE ++++M RL ++
Sbjct: 916 TQLEMKLQAETDLYAEAEEMRVRLEAKKQELEEVLHEMETRLEEEEERSLSLQQEKKDME 975
Query: 2845 ETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYD-------XXXXXXX 3003
+ ++ +K V+ +D +
Sbjct: 976 QQLQLMEAHIVEEEDARQKLQLEKVAVEGKVKKLEEDVLFMEDQNNKLQKGVFLHLQERK 1035
Query: 3004 XXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLA 3183
L++ L + EE++K+ K K + E+ + +LE + +E + + ++E+ KRK+ A
Sbjct: 1036 ILEERMADLSSNLAEEEEKSKNLTKLKSKHESMISDLEVRMKKEEKGRQDMEKAKRKVEA 1095
Query: 3184 ELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDE 3363
EL D + A+ ++EEL QL ++EELQ +EES+ K++R+++ I E
Sbjct: 1096 ELADLHEQHADLQAQLEELRAQLAAKEEELQATQASLEEESSQRGAAVKRVRELEALISE 1155
Query: 3364 LREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDE 3519
L+ED+E ER+AR K E RR++ +L ++ ++ D +D Q+L +++++
Sbjct: 1156 LQEDLEAERSARAKVEAARRDLGEELNALRSELEDSLDTTAAQQELRAKREQ 1207
Score = 266 bits (679), Expect = 6e-69
Identities = 145/369 (39%), Positives = 237/369 (63%), Gaps = 4/369 (1%)
Frame = +1
Query: 3979 TRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVN-- 4152
TR K+ R RQ+E+++N+L+++ EE + +E+++ ++++K EE
Sbjct: 1420 TRQKLNLSGRLRQMEEDRNSLIEQLEEETEAKRVVERQVSNLSMQLSDSKKKLEEMSGTV 1479
Query: 4153 QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSE 4332
+ LEE +K+ RD+E + EE A +++ + + ++QQELED M+L++ R + E
Sbjct: 1480 EMLEEGKKRLQRDLEASHSEYEEKASAYDKLEKGRGRLQQELEDVLMDLDSQRQLVSNLE 1539
Query: 4333 KRQKKFES--QMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRV 4506
K+QKKF+ + EER K +RD E R++ETRVL+L + + LEE+++
Sbjct: 1540 KKQKKFDQVLMLGEERAVSCKFAEERDRAEAEAREKETRVLALARALQENQIALEEAEKT 1599
Query: 4507 RRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRL 4686
++L+ E++D IS+KDD GK+VH+LEKAKR LEA + +MR QMEELED LQ+AEDA+LRL
Sbjct: 1600 MKALRGEMEDIISSKDDVGKSVHDLEKAKRCLEAMVEEMRTQMEELEDELQVAEDAKLRL 1659
Query: 4687 EVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQ 4866
EV +QALK++ +R + +D EEKR+ LLKQ+R+LE ELE E++ + A +KK+E +
Sbjct: 1660 EVNSQALKAQHERELHARDEMGEEKRKQLLKQVRELEEELEEERKQRGQASGSKKKLEGE 1719
Query: 4867 IGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAV 5046
+ ++E Q+E +R ++E E Q E E++R A++++ A REA+R+ +A+
Sbjct: 1720 LKDVEDQMEATSRARDEAVKQLRKIQGQVKELQRELEDSRAAQKEVLASAREAERRSKAM 1779
Query: 5047 EAEREQLRE 5073
EA+ QL+E
Sbjct: 1780 EADVIQLQE 1788
Score = 122 bits (307), Expect = 8e-26
Identities = 196/965 (20%), Positives = 384/965 (39%), Gaps = 76/965 (7%)
Frame = +1
Query: 3037 QLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELE---QHKRKLLAELEDSKDH 3207
++ EE K + E +L ++ Q ++ + +++LE Q + L AE E+ +
Sbjct: 879 EMTQKEEELKAAKDLAVKAEAELKDISQKHSQLLEERTQLEMKLQAETDLYAEAEEMRVR 938
Query: 3208 LAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETE 3387
L K ++EE+ L TR +EE +Q++ +DM+ + + + E
Sbjct: 939 LEAKKQELEEV----------LHEMETRLEEEEERSLSLQQEKKDMEQQLQLMEAHIVEE 988
Query: 3388 RNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ-----DLMSRKDEEVNATKRAIEQ 3552
+AR K ++ + V +++K++ DVL D+ LQ L RK E +
Sbjct: 989 EDARQKLQLEKVAVEGKVKKLEEDVLFMEDQNNKLQKGVFLHLQERKILEERMADLSSNL 1048
Query: 3553 IQHTMEGK-IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQ 3729
+ + K + + K+K + +L ++++ +K R +EK + + + E AD+ ++ A LQ
Sbjct: 1049 AEEEEKSKNLTKLKSKHESMISDLEVRMKKEEKGRQDMEKAKRKVEAELADLHEQHADLQ 1108
Query: 3730 ASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFA 3909
A ++ + E L QA+L E + + ++ + L E E A A
Sbjct: 1109 AQLEELRAQLAAKEEELQATQASLEEESSQRGAAVKRVRELEALISELQEDLEAERSARA 1168
Query: 3910 NMQ---RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGL--R 4074
++ R L T A R ++ L +E G R
Sbjct: 1169 KVEAARRDLGEELNALRSELEDSLDTT----AAQQELRAKREQGGGLPEESHGGGGAHPR 1224
Query: 4075 AHLEKEIHAARQGAGEARRKA----------EESVNQQLEELRKKNLRDVEHLQKQ---- 4212
+ AR G G A+R A ES E + + R Q Q
Sbjct: 1225 SSNPGPETEARSGCGGAQRAAGAGQEGESWPGESQAGSGEGVCRSERRPAIPRQLQAGRG 1284
Query: 4213 LEESEV---AKERILQSKKKIQQELEDSSMELENVRASHRDSE----------------- 4332
+E EV A+ L +++ E L+N SH +
Sbjct: 1285 AQEEEVGGSAERPALALQRERAAEGGAERARLQNDGRSHGPASCSCQSCGDGNARPLPPS 1344
Query: 4333 ------KRQKKFESQMAEERVAVQK---ALLDRDAMSQELRDRETRV-------LSLLNE 4464
+R + E EE A Q+ A L E +R T LS +++
Sbjct: 1345 LPGGAGRRDESAERSGREEHQAEQRRVHAELAAPGCPGEAGERVTNSNGSRGSHLSHISD 1404
Query: 4465 VDIMKEHLEE--SDRVRR--SLQQELQDSISNKDDFGKNVHELEKAKR-------SLEAE 4611
++ L+E S+ R+ +L L+ +++ + + E +AKR +L +
Sbjct: 1405 SALLVVLLQELLSEETRQKLNLSGRLRQMEEDRNSLIEQLEEETEAKRVVERQVSNLSMQ 1464
Query: 4612 LNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRD 4791
L+D + ++EE+ +++ E+ + RL+ +A SE + S D + E+ R L +++ D
Sbjct: 1465 LSDSKKKLEEMSGTVEMLEEGKKRLQRDLEASHSEYEEKASAYD-KLEKGRGRLQQELED 1523
Query: 4792 LENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIE 4971
+ +L+++++ S +KK + Q+ L ++ V+ + EE E +
Sbjct: 1524 VLMDLDSQRQLVSNLEKKQKKFD-QVLMLGEERAVSCKFAEE----RDRAEAEAREKETR 1578
Query: 4972 CEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKG 5151
+A ++ L EA++ +A+ E E + + + + K
Sbjct: 1579 VLALARALQENQIALEEAEKTMKALRGEMEDIISSKDDV------------------GKS 1620
Query: 5152 GGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKT 5331
+ KR LEA + + + Q+E++ +L + +
Sbjct: 1621 VHDLEKAKRCLEAMV---------------------EEMRTQMEELEDELQVAEDAKLRL 1659
Query: 5332 EAEKQSLE-RSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANR 5508
E Q+L+ + R+ A+ E G + R + L +V+ LE++L E +++ A+
Sbjct: 1660 EVNSQALKAQHERELHARD---EMGEEKRKQ-----LLKQVRELEEELEEERKQRGQASG 1711
Query: 5509 AARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRN 5688
+ ++LE L D Q E RA ++A + L K + + L+R+L+++ R
Sbjct: 1712 SKKKLEGELKDVEDQMEATSRARDEAVKQLRKIQGQVKELQRELEDSRAAQKEVLASARE 1771
Query: 5689 VQREA 5703
+R +
Sbjct: 1772 AERRS 1776
Score = 87.4 bits (215), Expect = 4e-15
Identities = 92/433 (21%), Positives = 182/433 (41%), Gaps = 5/433 (1%)
Frame = +1
Query: 3028 LTTQLLDHEERAKHGVKAKGR-LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKD 3204
L +LL E R K + + R +E + L + L E + K +E+ L +L DSK
Sbjct: 1411 LLQELLSEETRQKLNLSGRLRQMEEDRNSLIEQLEEETEAKRVVERQVSNLSMQLSDSKK 1470
Query: 3205 HLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMET 3384
L E G VE L + +L+ + Y+E+++ ++K +Q ++++ D+++
Sbjct: 1471 KLEEMSGTVEMLEEGKKRLQRDLEASHSEYEEKASAYDKLEKGRGRLQQELEDVLMDLDS 1530
Query: 3385 ERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHT 3564
+ R++V+ LEK + K D+ ML +E + K A E+ +
Sbjct: 1531 Q-----------RQLVSNLEKKQ----KKFDQVLML------GEERAVSCKFAEERDRAE 1569
Query: 3565 MEGKIEEQKA-KFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRA 3741
E + +E + +R ++E +E+ +K L + + D+ + +
Sbjct: 1570 AEAREKETRVLALARALQENQIALEEAEKTMKALRGEMEDIISSKDDVGKSV-------H 1622
Query: 3742 DIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQR 3921
D++K ++ EA + E++ + E ++ + D R L E E HA M
Sbjct: 1623 DLEKAKRCLEAMVEEMRTQMEELEDELQVAEDAKLRLEVNSQALKAQHERELHARDEMGE 1682
Query: 3922 RLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHA 4101
+ + R+LE+E ++ +A G + LE E+
Sbjct: 1683 EKRKQL--------------------LKQVRELEEELEEERKQRGQASGSKKKLEGELKD 1722
Query: 4102 ARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQE-- 4275
R +E+V Q +K V+ LQ++LE+S A++ +L S ++ ++
Sbjct: 1723 VEDQMEATSRARDEAVKQ-----LRKIQGQVKELQRELEDSRAAQKEVLASAREAERRSK 1777
Query: 4276 -LEDSSMELENVR 4311
+E ++L+ VR
Sbjct: 1778 AMEADVIQLQEVR 1790
Score = 74.7 bits (182), Expect = 3e-11
Identities = 88/352 (25%), Positives = 146/352 (41%), Gaps = 34/352 (9%)
Frame = +1
Query: 4216 EESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKAL 4395
EE KE L++ K + + E EL+++ H SQ+ EER ++ L
Sbjct: 877 EEEMTQKEEELKAAKDLAVKAE---AELKDISQKH-----------SQLLEERTQLEMKL 922
Query: 4396 ---LDRDAMSQELRDR-ETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFG 4563
D A ++E+R R E + L + M+ LEE + SLQQE +D
Sbjct: 923 QAETDLYAEAEEMRVRLEAKKQELEEVLHEMETRLEEEEERSLSLQQEKKDMEQQLQLME 982
Query: 4564 KNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLE------VTNQALKSESDR 4725
++ E E A++ L+ E + ++++LE+++ ED +L+ + + + E
Sbjct: 983 AHIVEEEDARQKLQLEKVAVEGKVKKLEEDVLFMEDQNNKLQKGVFLHLQERKILEERMA 1042
Query: 4726 AISNKDVEAEEKRRGLLK-------QIRDLENELENEKRGKSGAVSHRKKIENQIGELEQ 4884
+S+ E EEK + L K I DLE ++ E++G+ ++K+E ++ +L +
Sbjct: 1043 DLSSNLAEEEEKSKNLTKLKSKHESMISDLEVRMKKEEKGRQDMEKAKRKVEAELADLHE 1102
Query: 4885 QLEVANRLKEEYXXXXXXXXXXXXEYQIECEE-------ARQAKEDIAALLR------EA 5025
Q EE Q EE A + ++ AL+ EA
Sbjct: 1103 QHADLQAQLEELRAQLAAKEEELQATQASLEEESSQRGAAVKRVRELEALISELQEDLEA 1162
Query: 5026 DRKFRA-VEAEREQLREANEGLMQARKQXXXXXXXXXXXRAK---GGGISSE 5169
+R RA VEA R L E L + RAK GGG+ E
Sbjct: 1163 ERSARAKVEAARRDLGEELNALRSELEDSLDTTAAQQELRAKREQGGGLPEE 1214
Score = 68.2 bits (165), Expect = 2e-09
Identities = 33/87 (37%), Positives = 57/87 (64%)
Frame = +1
Query: 5485 QEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMS 5664
+E+ A + R+ EK+L D T Q EDE++ +Q K+ EK+N++ + L+ QL+EAE+E
Sbjct: 1952 RERQANAKNLRQKEKKLKDLTIQMEDERKQAQQYKDQAEKANVRVKQLKLQLEEAEEEAQ 2011
Query: 5665 RERTKHRNVQREADDLLDANEQLTREL 5745
R R +QRE ++ +AN+ L+R++
Sbjct: 2012 RVAAGRRKLQRELEEASEANDALSRDV 2038
Score = 62.8 bits (151), Expect = 1e-07
Identities = 87/412 (21%), Positives = 165/412 (39%)
Frame = +1
Query: 3601 SRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHL 3780
+RQ EE+ + E+ K + K A+ E D++Q+ + L R ++ K
Sbjct: 874 TRQEEEMTQKEEELKAAKDLAVK----AEAELKDISQKHSQLLEERTQLEMK-------- 921
Query: 3781 MEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXX 3960
++ + +L E R ++ ++ +E+ H R EEE
Sbjct: 922 LQAETDLYAEAEEMRVRLEAKKQELEEVLHEMETRLEEEE-------------------- 961
Query: 3961 XXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAE 4140
R+ L+ EK D +++ + + AH+ +E ARQ + + A
Sbjct: 962 --------------ERSLSLQQEKK---DMEQQLQLMEAHIVEE-EDARQKL-QLEKVAV 1002
Query: 4141 ESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASH 4320
E ++LEE DV ++ Q + + LQ +K +++ + D S L
Sbjct: 1003 EGKVKKLEE-------DVLFMEDQNNKLQKGVFLHLQERKILEERMADLSSNLAEEEEKS 1055
Query: 4321 RDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESD 4500
++ K + K ES +++ V ++K R M + R E + L + ++ LEE
Sbjct: 1056 KNLTKLKSKHESMISDLEVRMKKEEKGRQDMEKAKRKVEAELADLHEQHADLQAQLEELR 1115
Query: 4501 RVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARL 4680
+ ++ELQ + ++ ++ K R LEA +++++ +E E AR
Sbjct: 1116 AQLAAKEEELQATQASLEEESSQRGAAVKRVRELEALISELQEDLEAERSARAKVEAARR 1175
Query: 4681 RLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGA 4836
L AL+SE + ++ + E L+ R+ L E G GA
Sbjct: 1176 DLGEELNALRSELEDSLDTTAAQQE------LRAKREQGGGLPEESHGGGGA 1221
Score = 57.0 bits (136), Expect = 5e-06
Identities = 92/436 (21%), Positives = 162/436 (37%), Gaps = 3/436 (0%)
Frame = +1
Query: 4306 VRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAM--SQELRDRETRVLSLLNEVDIMK 4479
++ + ++ E QK+ E + A++ +A L + SQ L +R + L E D+
Sbjct: 871 LQVTRQEEEMTQKEEELKAAKDLAVKAEAELKDISQKHSQLLEERTQLEMKLQAETDLYA 930
Query: 4480 EHLEESDRVR-RSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNL 4656
E E RVR + +QEL++ + + + E E+ SL+ E DM Q++ +E ++
Sbjct: 931 E--AEEMRVRLEAKKQELEEVLHEMET---RLEEEEERSLSLQQEKKDMEQQLQLMEAHI 985
Query: 4657 QIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGA 4836
EDAR +L++ + V E K + L + + +E++ ++G
Sbjct: 986 VEEEDARQKLQL---------------EKVAVEGKVKKLEEDVLFMEDQNNKLQKGVFLH 1030
Query: 4837 VSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALL 5016
+ RK +E ++ +L +N +EE E I E R KE+
Sbjct: 1031 LQERKILEERMADLS-----SNLAEEEEKSKNLTKLKSKHESMISDLEVRMKKEE----- 1080
Query: 5017 READRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKI 5196
KG + KR++EA++
Sbjct: 1081 -------------------------------------------KGRQDMEKAKRKVEAEL 1097
Query: 5197 AQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYK 5376
A ++ Q QLE++ L+ + Q T+A SLE
Sbjct: 1098 ADLH--------------EQHADLQAQLEELRAQLAAKEEELQATQA---SLEE------ 1134
Query: 5377 AKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQF 5556
ES + A ++ LEA + L++ L E + A R L + LN +
Sbjct: 1135 ------ESSQRGAAVKRVRELEALISELQEDLEAERSARAKVEAARRDLGEELNALRSEL 1188
Query: 5557 EDEKRANEQAKELLEK 5604
ED +EL K
Sbjct: 1189 EDSLDTTAAQQELRAK 1204
Score = 37.7 bits (86), Expect = 3.4
Identities = 22/57 (38%), Positives = 35/57 (60%)
Frame = +1
Query: 4120 EARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSS 4290
E RK + Q E K N+R V+ L+ QLEE+E +R+ ++K+Q+ELE++S
Sbjct: 1976 EDERKQAQQYKDQAE---KANVR-VKQLKLQLEEAEEEAQRVAAGRRKLQRELEEAS 2028
>gi|26337045|dbj|BAC32206.1| unnamed protein product [Mus musculus]
Length = 885
Score = 1168 bits (3021), Expect = 0.0
Identities = 577/888 (64%), Positives = 705/888 (78%), Gaps = 8/888 (0%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL V RA + +PAT A W +KL W+P + GF SIK E DEV+VEL + ++ +
Sbjct: 12 RYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMV 71
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDM+ELT LNEASVLHNLKDRYYS LIYTYSGLFCVVINPYK L
Sbjct: 72 NKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNL 131
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYSE++IE ++GKKRHEMPPHI+AI+++AYR MLQ+REDQSILCTGESGAGKTENTKKV
Sbjct: 132 PIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKV 191
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
IQYLAHVA + + + + N GELE QLLQANPILE+FGN+KTVKND
Sbjct: 192 IQYLAHVASSHKGRKDH--------------NIPGELERQLLQANPILESFGNAKTVKND 237
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFYQ+L G KS
Sbjct: 238 NSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKS 297
Query: 913 EYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 1092
+ LLEG +NYRFL N I +P D F T+ +M IMGF+ +EI S+++VVS+VL G
Sbjct: 298 DLLLEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFG 357
Query: 1093 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA 1272
N+ F +E+ +DQA + ++ V QK+CHLLG+ V+E +A L PRIKVGR++V KAQ +EQA
Sbjct: 358 NISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQA 417
Query: 1273 EFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICIN 1452
+FAVEA+AKA+YERLF+WLV RINK+LDRT RQGASFIGILDIAGFEIF++NSFEQ+CIN
Sbjct: 418 DFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCIN 477
Query: 1453 YTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDE 1623
YTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP IDLIE+P GVLALLDE
Sbjct: 478 YTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDE 537
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMD 1800
EC FPKA DK+FVEKL + H KF P ++ K+ F ++HYAG+VDY AD+WLMKNMD
Sbjct: 538 ECWFPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMD 597
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAFG--MRSRKGMFRTVSQLH 1968
PLN+NV L+ S+D FVA +WKD + G+ M ETAFG +++KGMFRTV QL+
Sbjct: 598 PLNDNVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLY 657
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
KE LTKLM TLRNT+P+FVRCIIPNHEK++GK++ +LVL+QLRCNGVLEGIRICRQGFPN
Sbjct: 658 KESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPN 717
Query: 2149 RVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAH 2328
R+ FQEFR RYEILTP+ IPK F+DGK++ +MI AL++D NLYRIGQSK+FFR GVLAH
Sbjct: 718 RIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAH 777
Query: 2329 LEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRL 2508
LEEERDLK+T +I+ FQA CRG+L+R+ + N AYLKLR+WQWWR+
Sbjct: 778 LEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRV 837
Query: 2509 FTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQV 2652
FTKVKPLLQVTR ++E++AKD+EL KE+ K+E + E E+K Q+
Sbjct: 838 FTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQL 885
>gi|45382109|ref|NP_990097.1| myosin heavy chain [Gallus gallus]
gi|7248371|dbj|BAA92710.1| myosin heavy chain [Gallus gallus]
Length = 1937
Score = 1164 bits (3011), Expect = 0.0
Identities = 677/1900 (35%), Positives = 1062/1900 (55%), Gaps = 18/1900 (0%)
Frame = +1
Query: 64 AWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIE 243
A+ +K CWVPD + ++ I + +V VE D R +TI DDVQ NPPKFD IE
Sbjct: 28 AFDGKKKCWVPDDKKAYVEAEITESSGGKVTVETTD-GRTMTIKEDDVQSMNPPKFDMIE 86
Query: 244 DMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRH 423
DM+ LT+LNEASVL+NL+ RY + +IYTYSGLFCV INPYK LP+Y +++ +KGK+R
Sbjct: 87 DMAMLTHLNEASVLYNLRKRYSNWMIYTYSGLFCVTINPYKWLPVYKSEVVAAYKGKRRS 146
Query: 424 EMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLN 603
E PPHIF+IAD AY ML+ RE+QS+L TGESGAGKT NTK+VIQY A VA
Sbjct: 147 EAPPHIFSIADNAYHDMLRNRENQSMLITGESGAGKTVNTKRVIQYFATVA--------- 197
Query: 604 AAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSG 783
A + +P + G LE Q++QANP LEAFGN+KT++NDNSSRFGKFIRI+F +G
Sbjct: 198 ALGEPGKKSQPATKTG-GTLEDQIIQANPALEAFGNAKTLRNDNSSRFGKFIRIHFGTTG 256
Query: 784 YISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVN 957
+S A+IE YLLEKSRV+ Q ER +HIFYQIL G E + LL + +Y F
Sbjct: 257 KLSSADIEIYLLEKSRVIFQQPGERDYHIFYQILSG-KKPELLDMLLVSTNPYDYHFCSQ 315
Query: 958 RGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAML 1137
+T+ N+DD +E +T +M I+GF DE ++ A++ GN++F Q + +QA
Sbjct: 316 GVVTVDNLDDGEELMATDQAMDILGFVPDEKYGAYKLTGAIMHFGNMKFKQRPREEQAEA 375
Query: 1138 QDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERL 1317
K +L+G+ +L K L PR+KVG E+V K Q+ EQ +AV A++KA Y+R+
Sbjct: 376 DGTESADKAAYLMGINSSDLVKGLLHPRVKVGNEYVTKGQSVEQVLYAVGALSKAVYDRM 435
Query: 1318 FKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMF 1497
FKWLV RINK+LD T FIG+LDIAGFEIFD NSFEQ+CINYTNEKLQQ FN+ MF
Sbjct: 436 FKWLVVRINKTLD-TKLPRQFFIGVLDIAGFEIFDFNSFEQLCINYTNEKLQQFFNHHMF 494
Query: 1498 ILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQK 1677
+LEQEEY++EGIEW FIDFG+DLQ IDLIEKP+G+L++L+EEC+FPKA D +F KL
Sbjct: 495 VLEQEEYKKEGIEWVFIDFGMDLQACIDLIEKPLGILSILEEECMFPKATDMTFKAKLYD 554
Query: 1678 TH-NKHPKFIV--PDMRSK--SHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNST 1842
H K P PD + K +HF ++HYAG V Y+ WL KN DPLNE VVG+ Q S+
Sbjct: 555 NHLGKSPNLQKPRPDKKRKYEAHFELIHYAGSVPYNIIGWLEKNKDPLNETVVGIFQKSS 614
Query: 1843 DPFVAGIWKDAEFAGICAAEMNETAFGMRSRK--GMFRTVSQLHKEQLTKLMTTLRNTSP 2016
+ +A +++ + G +A+ G + RK F+TVS LHKE L KLMT LR+T+P
Sbjct: 615 NKLLASLFE--SYVGADSADQG----GEKKRKKGASFQTVSSLHKENLNKLMTNLRSTAP 668
Query: 2017 HFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTP 2196
HFVRCIIPN K G++++ LVL QLRCNGVLEGIRICR+GFPNRV + +F+ RY IL P
Sbjct: 669 HFVRCIIPNESKTPGEMDAFLVLHQLRCNGVLEGIRICRKGFPNRVLYADFKQRYRILNP 728
Query: 2197 DVIPKN-FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMN 2373
IP++ F+D +++ K++ +LDID N YR G +KVFF+ G+L HLEE RD +L ++
Sbjct: 729 GAIPEDKFVDSRKAAEKLLASLDIDHNQYRFGHTKVFFKAGLLGHLEEMRDERLAKILTM 788
Query: 2374 FQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDD 2553
QA+ RG L R + N A++ ++NW W +LF K+KPLL+ T+
Sbjct: 789 IQARARGRLMRIEFQKIVERRDALLVIQWNIRAFMAVKNWPWMKLFFKIKPLLKSAETEK 848
Query: 2554 EIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGR 2733
E+ +E KE L K E +E E+K ++ E+ + QLQ E + A+ ++
Sbjct: 849 EMANMKEEFLKLKEALEKSEARRKELEEKQVSLVQEKNDLLLQLQAEQDTLADAEERCDL 908
Query: 2734 LQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXD 2913
L +LE V ++ +R+ +RK + + +
Sbjct: 909 LIKSKIQLEAKVKELTERVEDEEEMNSELTSKKRKLEDECSELKKDIDDLEITLAKVEKE 968
Query: 2914 KTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRL 3093
K + + + L E++ KAK +L
Sbjct: 969 KHATENKVKNLTEEMATLDENISKLTKEKKSLQEAHQQVLDDLQAEEDKVNTLSKAKVKL 1028
Query: 3094 ENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEEL 3273
E Q+ +LE L +E++ + +LE+ KRKL +L+ +++ + + ++ +L K++ E+
Sbjct: 1029 EQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESVMDLENDKLQMEEKLKKKEFEM 1088
Query: 3274 QHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVK 3453
++ ++E A V +QK+++++Q I+EL E++E ER AR K E R ++ +LE V
Sbjct: 1089 SQLNSKIEDEQAIVMQLQKKIKELQARIEELEEELEAERAARAKVEKQRSDLARELE-VL 1147
Query: 3454 GDVLDKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
+ L++ AT Q M++K E E R +E+ E + K + V E+ +Q
Sbjct: 1148 SERLEEAGGATAAQLEMNKKREAEFLKLARDLEEATLHYEATAAALRKKHADSVAEMGEQ 1207
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAES 3810
++ ++ + +LEK++++ E D+ + +A+ +K + +E HL E + L E
Sbjct: 1208 LDNLQRVKQKLEKEKSELKMEVDDLTSNMEQTVKGKANAEKLCRTYEDHLNETKTKLDEM 1267
Query: 3811 DEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLK 3990
L Q + + E R EE+E + + R + T+ K
Sbjct: 1268 TRLMNDLTTQKTKLQSENGEFVRQLEEKESLISQLSRGKTSFTQQIEELRRQLEEETKSK 1327
Query: 3991 IANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEEL 4170
A + + + + L ++ EE + +A L++ + + R K E Q+ EEL
Sbjct: 1328 NALAHALQAARHDCDLLREQYEEEQEAKAELQRALSKGNAEVAQWRTKYETDAIQRTEEL 1387
Query: 4171 ---RKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQ 4341
+KK ++ ++ +E + + ++K ++Q ELED ++LE ++ +K+Q
Sbjct: 1388 EDAKKKLAARLQEAEEAIEAANAKCSSLEKTKHRLQNELEDMMIDLEKANSAAASLDKKQ 1447
Query: 4342 KKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQ 4521
+ F+ + + + +++ + +A +E R T + L N + +HLE R ++LQ
Sbjct: 1448 RGFDKIINDWKQKYEESQAELEASQKEARSLSTELFKLKNAYEETLDHLETLKRENKNLQ 1507
Query: 4522 QELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQ 4701
+E+ D + + KN+HE+EK K+ +E E +++++ +EE E L+ E LR ++
Sbjct: 1508 EEISDLTNQISEGNKNLHEIEKVKKQVEQEKSEVQLALEEAEGALEHEESKTLRFQLELS 1567
Query: 4702 ALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELE 4881
LK++ +R ++ KD E E RR + I L++ L++E R ++ A+ +KK+E + E+E
Sbjct: 1568 QLKADFERKLAEKDEEMENIRRNQQRTIDSLQSTLDSEARSRNEAIRLKKKMEGDLNEME 1627
Query: 4882 QQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAERE 5061
QL ANR E E Q++ ++ ED+ L +DR+ +++E +
Sbjct: 1628 IQLSHANRHAAEATKSARGLQTQIKELQVQLDDLGHLNEDLKEQLAVSDRRNNLLQSELD 1687
Query: 5062 QLREANEGLMQARK----QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQ 5229
+LR + +ARK + + + + +K++LE I+Q
Sbjct: 1688 ELRALLDQTERARKLAEHELLEATERVNLLHTQNTSLIN-QKKKLEGDISQMQNEVEESI 1746
Query: 5230 SNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQ 5409
C A +K +KA + +L E+ + E K+++E++ +D + ++ E E A
Sbjct: 1747 QECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQKRLDEAEQIAL 1806
Query: 5410 SRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAK 5589
+ Q+ LE++V+ LE++L E + + A + AR+ E+R+ + T Q E++K+ + +
Sbjct: 1807 KGGKKQIQKLESRVRELENELENELRRNSDAQKGARKFERRIKEVTYQSEEDKKNLARMQ 1866
Query: 5590 ELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+L++K LK ++ + Q +EAE + + +K+R Q + DD
Sbjct: 1867 DLIDKLQLKVKSYKHQAEEAEAQANLYLSKYRKQQHDLDD 1906
Score = 104 bits (259), Expect = 3e-20
Identities = 146/749 (19%), Positives = 312/749 (41%), Gaps = 25/749 (3%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKR 3759
E++ A + +L + +E+ + +R +LE++Q QE+ D+ ++ Q + AD +++
Sbjct: 847 EKEMANMKEEFLKLKEALEKSEARRKELEEKQVSLVQEKNDLLLQLQAEQDTLADAEERC 906
Query: 3760 KIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAX 3939
+ ++++A + E E RV +EEE M L +
Sbjct: 907 DLLIKSKIQLEAKVKELTE--------------------RVEDEEE-----MNSELTS-- 939
Query: 3940 XXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAAR---Q 4110
+ R+LEDE + L + ++ E A +EKE HA +
Sbjct: 940 ----------------------KKRKLEDECSELKKDIDDLEITLAKVEKEKHATENKVK 977
Query: 4111 GAGEARRKAEESVNQQLEELRKKNLRDV-EHLQKQLEESEVAKERILQSKKKIQQELEDS 4287
E +E++++ +E KK+L++ + + L+ E + ++K K++Q+++D
Sbjct: 978 NLTEEMATLDENISKLTKE--KKSLQEAHQQVLDDLQAEEDKVNTLSKAKVKLEQQVDDL 1035
Query: 4288 SMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEV 4467
LE + D E+ ++K E + + +V D+ M ++L+ +E E+
Sbjct: 1036 EGSLEQEKKVRMDLERAKRKLEGDLKLTQESVMDLENDKLQMEEKLKKKEF-------EM 1088
Query: 4468 DIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELE 4647
+ +E+ + LQ+++++ + ++ + + A+ +E + +D+ ++E L
Sbjct: 1089 SQLNSKIEDEQAIVMQLQKKIKELQARIEELEEELEAERAARAKVEKQRSDLARELEVLS 1148
Query: 4648 DNLQIAEDARL-RLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRG 4824
+ L+ A A +LE+ NK EAE LK RDLE E
Sbjct: 1149 ERLEEAGGATAAQLEM--------------NKKREAE-----FLKLARDLE---EATLHY 1186
Query: 4825 KSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDI 5004
++ A + RKK + + E+ +QL+ R+K++ E ++E ++ E
Sbjct: 1187 EATAAALRKKHADSVAEMGEQLDNLQRVKQKLEKEKS-------ELKMEVDDLTSNMEQT 1239
Query: 5005 AALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGI--SSEEKR 5178
A++ R E + L E L + + +++ G EEK
Sbjct: 1240 VKGKANAEKLCRTYE---DHLNETKTKLDEMTRLMNDLTTQKTKLQSENGEFVRQLEEKE 1296
Query: 5179 RLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQL----EQITTDLSMERTLNQKTEAEKQ 5346
L +++++ ++++ K++ L + D + R ++ + K
Sbjct: 1297 SLISQLSRGKTSFTQQIEELRRQLEEETKSKNALAHALQAARHDCDLLREQYEEEQEAKA 1356
Query: 5347 SLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLE 5526
L+R+ A++ + + ++ A + LE + L +L + AAN LE
Sbjct: 1357 ELQRALSKGNAEVAQWRTKYETDAIQRTEELEDAKKKLAARLQEAEEAIEAANAKCSSLE 1416
Query: 5527 KRLNDTTQQFEDE----KRANEQAKELLEKSNLKNR---NLRRQLDEAEDEMSRERTKHR 5685
K + + ED ++AN A L +K ++ + +++ +E++ E+ + + R
Sbjct: 1417 KTKHRLQNELEDMMIDLEKANSAAASLDKKQRGFDKIINDWKQKYEESQAELEASQKEAR 1476
Query: 5686 NVQREA-------DDLLDANEQLTRELMN 5751
++ E ++ LD E L RE N
Sbjct: 1477 SLSTELFKLKNAYEETLDHLETLKRENKN 1505
>gi|20891813|ref|XP_147228.1| myosin heavy chain 11, smooth muscle
[Mus musculus]
Length = 1938
Score = 1163 bits (3009), Expect = 0.0
Identities = 617/1454 (42%), Positives = 928/1454 (63%), Gaps = 13/1454 (0%)
Frame = +1
Query: 1423 INSFEQICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM- 1599
+NSFEQ+CINYTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP I+LIE+P
Sbjct: 468 VNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNN 527
Query: 1600 --GVLALLDEECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYS 1770
GVLALLDEEC FPKA DKSFVEKL HPKF P ++ K+ F+++HYAG+VDY+
Sbjct: 528 PPGVLALLDEECWFPKATDKSFVEKLCSEQGNHPKFQKPKQLKDKTEFSIIHYAGKVDYN 587
Query: 1771 ADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWKDAE-FAGICA-AEMNETAF--GMRSRK 1938
A WL KNMDPLN+NV L+ S+D FVA +WKD + G+ A+M E++ +++K
Sbjct: 588 ASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKK 647
Query: 1939 GMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEG 2118
GMFRTV QL+KEQL KLMTTLRNT+P+FVRCIIPNHEK+SGK+++ LVLEQLRCNGVLEG
Sbjct: 648 GMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEG 707
Query: 2119 IRICRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSK 2298
IRICRQGFPNR+ FQEFR RYEIL + IPK F+DGK++ MI AL++D NLYRIGQSK
Sbjct: 708 IRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSK 767
Query: 2299 VFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYL 2478
+FFRTGVLAHLEEERDLK+T +IM FQA CRG+L+R+ +T N AYL
Sbjct: 768 IFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFTKRQQQLTAMKVIQRNCAAYL 827
Query: 2479 KLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIV 2658
KLRNWQWWRLFTKVKPLLQVTR ++E++AK++E++ KER K E + +E E+K Q+
Sbjct: 828 KLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEEEMQKIKERQQKAETELKELEQKHTQLAE 887
Query: 2659 ERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRK 2838
E+ ++QEQLQ E+E AE +++R RL + QELE I+++M RL R+K
Sbjct: 888 EKTLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKK 947
Query: 2839 QMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXX 3018
+ + D +K + D
Sbjct: 948 MAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDDILVMDDQNSKLSKERKLLEER 1007
Query: 3019 XXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDS 3198
LTT L + EE+AK+ K K + E+ + ELE L +E + + ELE+ KRKL + D
Sbjct: 1008 VSDLTTNLAEEEEKAKNLTKLKSKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF 1067
Query: 3199 KDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDM 3378
+ +A+ ++ EL QL K++EELQ L R DEE A K++R+++ I +L+ED+
Sbjct: 1068 HEQIADLQAQIAELKMQLAKKEEELQAALARLDEEIAQKNNALKKIRELEGHISDLQEDL 1127
Query: 3379 ETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQ 3558
++ER ARNKAE +R++ +LE +K ++ D +D Q+L +++++EV K+A+++
Sbjct: 1128 DSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEET 1187
Query: 3559 HTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASR 3738
+ E +++E + K ++ VEEL +Q+EQ K+ ++ L+K + ++E AD+A E+ +L ++
Sbjct: 1188 RSHEAQVQEMRQKHTQAVEELTEQLEQFKRAKANLDKSKQTLEKENADLAGELRVLGQAK 1247
Query: 3739 ADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
+++ K+K E L ++Q+ ++ + + L D++ + ++E++ + + E E +
Sbjct: 1248 QEVEHKKKKLEVQLQDLQSKCSDGERARAELSDKVHKLQNEVESVTGMLNEAEGKAIKLA 1307
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ +A+ TR K+ + RQLEDE+N+L D+ +E + +LE+ +
Sbjct: 1308 KDVASLGSQLQDTQELLQEETRQKLNVSTKLRQLEDERNSLQDQLDEEMEAKQNLERHVS 1367
Query: 4099 AARQGAGEARRKAEE--SVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQ 4272
++++K ++ S + +EE +K+ +++E L +Q EE A +++ ++K ++QQ
Sbjct: 1368 TLNIQLSDSKKKLQDFASTIEVMEEGKKRLQKEMEGLSQQYEEKAAAYDKLEKTKNRLQQ 1427
Query: 4273 ELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLS 4452
EL+D ++L+N R + EK+QKKF+ +AEE+ K +RD E R++ET+ LS
Sbjct: 1428 ELDDLVVDLDNQRQLVSNLEKKQKKFDQLLAEEKNISSKYADERDRAEAEAREKETKALS 1487
Query: 4453 LLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQ 4632
L ++ E EE +R + L+ E++D +S+KDD GKNVHELEK+KR+LE ++ +M+ Q
Sbjct: 1488 LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQ 1547
Query: 4633 MEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELEN 4812
+EELED LQ EDA+LRLEV QALK + +R + +D + EEKRR L +Q+ + E ELE+
Sbjct: 1548 LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELED 1607
Query: 4813 EKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQA 4992
E++ ++ A + +KK+E + +LE Q + A + +EE ++Q E ++AR +
Sbjct: 1608 ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELDDARAS 1667
Query: 4993 KEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRA---KGGGIS 5163
+++I A +E ++K +++EA+ QL+E +ARKQ A G
Sbjct: 1668 RDEIFATSKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNTL 1727
Query: 5164 SEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEK 5343
+EKRRLEA+IAQ Q N E D+ RKA +Q EQ++ +L+ ER+ QK E+ +
Sbjct: 1728 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATLQAEQLSNELATERSTAQKNESAR 1787
Query: 5344 QSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRL 5523
Q LER N++ ++K+ E+E +++ ++ +AALEAK+ LE+Q+ E +EK AA ++ ++
Sbjct: 1788 QQLERQNKELRSKLQEVEGAVKAKLKSTVAALEAKIAQLEEQVEQEAREKQAATKSLKQK 1847
Query: 5524 EKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREA 5703
+K+L + Q EDE++ EQ KE EK N K + L+RQL+EAE+E R R +QRE
Sbjct: 1848 DKKLKEVLLQVEDERKMAEQYKEQAEKGNTKVKQLKRQLEEAEEESQRINANRRKLQREL 1907
Query: 5704 DDLLDANEQLTREL 5745
D+ ++NE + RE+
Sbjct: 1908 DEATESNEAMGREV 1921
Score = 468 bits (1204), Expect = e-130
Identities = 233/380 (61%), Positives = 290/380 (76%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
D ++L V + + P A W +KL WVP + +GF SIK E DEV+VELV+ ++V
Sbjct: 10 DEKFLFVDKNFMNSPMAQADWVAKKLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKV 69
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
T+ +DD+QK NPPKF K+EDM+ELT LNEASVLHNL++RY+S LIYTYSGLFCVV+NPYK
Sbjct: 70 TVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYK 129
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
LPIYSE +++ +KGKKRHEMPPHI+AIADTAYRSMLQ+REDQSILCTGESGAGKTENTK
Sbjct: 130 YLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTK 189
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVIQYLA VA + + K ++ GELE QLLQANPILEAFGN+KTVK
Sbjct: 190 KVIQYLAVVASSHKGKKDSSIT--------------GELEKQLLQANPILEAFGNAKTVK 235
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
NDNSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFY +L G K
Sbjct: 236 NDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYLLAGAKEKM 295
Query: 907 KSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLL 1086
KS+ LLE ++Y FL N + +P D + F T+ +M IMGF ++E +I++VVS+VL
Sbjct: 296 KSDLLLESFNSYTFLSNGFVPIPAAQDDEMFQETLEAMSIMGFNEEEQLAILKVVSSVLQ 355
Query: 1087 LGNLEFTQEKKSDQAMLQDD 1146
LGN+ F +E+ +DQA + D+
Sbjct: 356 LGNIVFKKERNTDQASMPDN 375
Score = 160 bits (406), Expect = 3e-37
Identities = 195/914 (21%), Positives = 384/914 (41%), Gaps = 58/914 (6%)
Frame = +1
Query: 2512 TKVKPLLQVTRTDDEIRAKDDEL-RATKERLL-KMEHDFRENEKKLDQVIVERAVIQEQL 2685
TK+K + ++ E+R K +E R E+L K+E D + +++ + + A ++ QL
Sbjct: 1026 TKLKSKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQL 1085
Query: 2686 -QQESENSAELDDIRGRLQTRN------QELEYIVNDMRDRLSXXXXXXXXXXXXRRKQM 2844
++E E A L + + +N +ELE ++D+++ L +R
Sbjct: 1086 AKKEEELQAALARLDEEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLG 1145
Query: 2845 ETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXX 3024
E + + +Q +++
Sbjct: 1146 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHTQAV 1205
Query: 3025 GLTTQLLDHEERAKHGV-KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSK 3201
T+ L+ +RAK + K+K LE + +L +L Q K E+E K+KL +L+D +
Sbjct: 1206 EELTEQLEQFKRAKANLDKSKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEVQLQDLQ 1265
Query: 3202 DHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDME 3381
++ EL++++ K E++ +E + K + + + + + +E ++
Sbjct: 1266 SKCSDGERARAELSDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLGSQLQDTQELLQ 1325
Query: 3382 TERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNA----TKRAIE 3549
E R K ++ + + QLE + + D++DE + + R +N +K+ ++
Sbjct: 1326 EE--TRQKLNVSTK--LRQLEDERNSLQDQLDEEMEAKQNLERHVSTLNIQLSDSKKKLQ 1381
Query: 3550 QIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQ 3729
T+E +EE K + +++E L Q E+ +LEK +N+ QE D+ ++ +
Sbjct: 1382 DFASTIE-VMEEGKKRLQKEMEGLSQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1440
Query: 3730 ASRADIDKKRKIHEAHLMEIQANLAE--SDEHKRTLIDQLERSRDELDHLNRVREEEEHA 3903
++++KK+K + L E + N++ +DE R + E+ L L R EE A
Sbjct: 1441 QLVSNLEKKQKKFDQLLAE-EKNISSKYADERDRAEAEAREKETKALS-LARALEEALEA 1498
Query: 3904 FANMQR--RLATAXXXXXXXXXXXXXXTRLKIANINRA------------RQLEDEKNAL 4041
++R ++ A ++ RA +LEDE A
Sbjct: 1499 KEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1558
Query: 4042 LDEKEEAE----GLRAHLEKEIHAARQGAGEARRKAEESVNQQLEEL------------- 4170
D K E L+ E+++ A + E RR+ + +++ EL
Sbjct: 1559 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1618
Query: 4171 RKKNLRDVEHLQKQLEESEVAKERILQSKKKIQ-------QELEDSSMELENVRASHRDS 4329
+KK D++ L+ Q + + +E ++ +K+Q +EL+D+ + + A+ +++
Sbjct: 1619 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELDDARASRDEIFATSKEN 1678
Query: 4330 EKRQKKFES---QMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESD 4500
EK+ K E+ Q+ E+ A ++A D +EL + LS N + K LE
Sbjct: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNTLQDEKRRLEA-- 1736
Query: 4501 RVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARL 4680
R+ + L++EL++ N + V KA E N++ + + N E AR
Sbjct: 1737 RIAQ-LEEELEEEQGNMEAMSDRV---RKATLQAEQLSNELATERSTAQKN----ESARQ 1788
Query: 4681 RLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIE 4860
+LE N+ L+S+ + + L +I LE ++E E R K A K+ +
Sbjct: 1789 QLERQNKELRSKLQEVEGAVKAKLKSTVAALEAKIAQLEEQVEQEAREKQAATKSLKQKD 1848
Query: 4861 NQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKF- 5037
++ E+ Q+E ++ E+Y + + + EEA + + I A R+ R+
Sbjct: 1849 KKLKEVLLQVEDERKMAEQYKEQAEKGNTKVKQLKRQLEEAEEESQRINANRRKLQRELD 1908
Query: 5038 RAVEAEREQLREAN 5079
A E+ RE N
Sbjct: 1909 EATESNEAMGREVN 1922
Score = 95.9 bits (237), Expect = 1e-17
Identities = 119/601 (19%), Positives = 233/601 (37%), Gaps = 39/601 (6%)
Frame = +1
Query: 4066 GLRAHLEKE-------IHAARQGA--GEARRKAEESVNQQLEELR--KKNLRDVEHLQKQ 4212
G+ AHLE+E + A Q G RKA QQL ++ ++N L+
Sbjct: 773 GVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFTKRQQQLTAMKVIQRNCAAYLKLRNW 832
Query: 4213 LEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFE---SQMAEERVAV 4383
K + L + ++E++ E++ ++ + +E K+ E +Q+AEE+ +
Sbjct: 833 QWWRLFTKVKPLLQVTRQEEEMQAKEEEMQKIKERQQKAETELKELEQKHTQLAEEKTLL 892
Query: 4384 QKALLDRDAMSQELRDRETRVLSLLNEVDI----MKEHLEESDRVRRSLQQELQDSISNK 4551
Q+ L + E + R+ + E++ M+ LEE + + LQ E +
Sbjct: 893 QEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQM 952
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAI 4731
D + + E E A++ L+ E ++++LED++ + +D +L + L+
Sbjct: 953 LDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDDILVMDDQNSKLSKERKLLEERVSDLT 1012
Query: 4732 SNKDVEAEEKRRGLLK-------QIRDLENELENEKRGKSGAVSHRKKIEN--------- 4863
+N E EEK + L K I +LE L+ E++ + ++K+E
Sbjct: 1013 TNL-AEEEEKAKNLTKLKSKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQI 1071
Query: 4864 -----QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREAD 5028
QI EL+ QL + +EE + ++ R+ + I+ L + D
Sbjct: 1072 ADLQAQIAELKMQLA---KKEEELQAALARLDEEIAQKNNALKKIRELEGHISDLQEDLD 1128
Query: 5029 RKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXX 5208
+ A +Q R+ E L + + + KR E + +
Sbjct: 1129 SERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQ------ELRAKREQEVTVLKKA 1182
Query: 5209 XXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKIT 5388
++ +Q+ Q +E++T L + + KQ+LE+ N D
Sbjct: 1183 LDEETRSHEAQVQEMRQKHTQA-VEELTEQLEQFKRAKANLDKSKQTLEKENAD------ 1235
Query: 5389 ELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEK 5568
L +L V GQ K ++LE +L D + D +
Sbjct: 1236 -----------------------LAGELRVLGQAKQEVEHKKKKLEVQLQDLQSKCSDGE 1272
Query: 5569 RANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
RA + + + K + ++ L+EAE + + ++ + D + ++ TR+ +
Sbjct: 1273 RARAELSDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLGSQLQDTQELLQEETRQKL 1332
Query: 5749 N 5751
N
Sbjct: 1333 N 1333
>gi|18859641|ref|NP_542766.1| myosin, heavy polypeptide 7, cardiac
muscle, beta; myosin heavy chain, cardiac muscle, fetal
[Mus musculus]
gi|16508127|gb|AAL17913.1| beta myosin heavy chain [Mus musculus]
Length = 1935
Score = 1155 bits (2988), Expect = 0.0
Identities = 669/1895 (35%), Positives = 1067/1895 (56%), Gaps = 17/1895 (0%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K +VPD E F+ I +V E + + VT+ D V + NPPKFDKIEDM+
Sbjct: 34 KKDVFVPDDKEEFVKAKIVSREGGKVTAE-TENGKTVTVKEDQVMQQNPPKFDKIEDMAM 92
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LT+L+E +VL+NLK+RY S +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PP
Sbjct: 93 LTFLHEPAVLYNLKERYASWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPP 152
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIF+I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A A ++S
Sbjct: 153 HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIA-AIGDRS------ 205
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
K D G LE Q++QANP LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++
Sbjct: 206 -----KKDQTPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLAS 260
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYL-----LEGVDNYRFLVNR 960
A+IE YLLEKSRV+ Q + ER +HIFYQIL + +K E L +Y F+
Sbjct: 261 ADIETYLLEKSRVIFQLKAERDYHIFYQIL----SNKKPELLDMLLITNNPYDYAFISQG 316
Query: 961 GITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQ 1140
T+ ++DD +E +T ++ ++GF +E +SI ++ A++ GN++F Q+++ +QA
Sbjct: 317 ETTVASIDDSEELMATDSAFDVLGFTPEEKNSIYKLTGAIMHFGNMKFKQKQREEQAEPD 376
Query: 1141 DDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLF 1320
K +L+GL +L K PR+KVG E+V K QN +Q +A+ A+AK+ YE++F
Sbjct: 377 GTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVSYAIGALAKSVYEKMF 436
Query: 1321 KWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFI 1500
W+VTRIN +L+ T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF+
Sbjct: 437 NWMVTRINATLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFV 495
Query: 1501 LEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKT 1680
LEQEEY++EGIEW FIDFG+DLQ IDLIEKPMG++++L+EEC+FPKA D +F KL
Sbjct: 496 LEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLYDN 555
Query: 1681 H-NKHPKFIVP---DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDP 1848
H K F P + ++HF++VHYAG VDY+ WL KN DPLNE VVGL Q S+
Sbjct: 556 HLGKSNNFQKPRNVKGKQEAHFSLVHYAGTVDYNILGWLQKNKDPLNETVVGLYQKSSLK 615
Query: 1849 FVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVR 2028
++ ++ A +AG A + G + F+TVS LH+E L KLMT LR+T PHFVR
Sbjct: 616 LLSNLF--ANYAGADAPA--DKGKGKAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVR 671
Query: 2029 CIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIP 2208
CIIPN K G +++ LV+ QLRCNGVLEGIRICR+GFPNR+ + +FR RY IL P IP
Sbjct: 672 CIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIP 731
Query: 2209 K-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQ 2385
+ FID ++ K++ +LDID N Y+ G +KVFF+ G+L LEE RD +L+ +I QAQ
Sbjct: 732 EGQFIDSRKGAEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQ 791
Query: 2386 CRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRA 2565
RG LSR + N A++ ++NW W +L+ K+KPLL+ T+ E+
Sbjct: 792 SRGVLSRMEFKKLLERRDSLLIIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMAT 851
Query: 2566 KDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTR 2745
+E K+ L K E +E E+K+ ++ E+ +Q Q+Q E +N A+ ++ +L
Sbjct: 852 MKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKN 911
Query: 2746 NQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNV 2925
+LE V +M +RL +RK + + +K
Sbjct: 912 KIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHAT 971
Query: 2926 DQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQL 3105
+ + L E++ KAK +LE Q+
Sbjct: 972 ENKVKNLTEEMAGLDEIIVKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQV 1031
Query: 3106 HELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQL 3285
+LE L +E++ + +LE+ KRKL +L+ +++ + + ++L+ +L K+D EL
Sbjct: 1032 DDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALN 1091
Query: 3286 TRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVL 3465
R ++E A + +QK+++++Q I+EL E++E ER AR K E R ++ +LE++ + L
Sbjct: 1092 ARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEI-SERL 1150
Query: 3466 DKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQH 3642
++ AT +Q M++K E E +R +E+ E + K + V EL +QI+
Sbjct: 1151 EEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 1210
Query: 3643 KKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHK 3822
++ + +LEK++++ E D+ + + ++A+++K + E + E ++ E+
Sbjct: 1211 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSV 1270
Query: 3823 RTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANI 4002
L Q + + E L+R +E+E + + R T + K A
Sbjct: 1271 NDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALA 1330
Query: 4003 NRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN 4182
+ + + + L ++ EE +A L++ + A + R K E Q+ EEL +
Sbjct: 1331 HALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAK 1390
Query: 4183 LRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFE 4353
+ + LQ E E + + ++K ++Q E+ED +++E A+ +K+Q+ F+
Sbjct: 1391 KKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFD 1450
Query: 4354 SQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQ 4533
+AE + +++ + ++ +E R T + L N + EHLE R ++LQ+E+
Sbjct: 1451 KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEIS 1510
Query: 4534 DSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKS 4713
D GK++HELEK ++ LEAE +++ +EE E +L+ E LR ++ +K+
Sbjct: 1511 DLTEQLGSTGKSIHELEKIRKQLEAEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKA 1570
Query: 4714 ESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLE 4893
E +R ++ KD E E+ +R L+ + L+ L+ E R ++ A+ +KK+E + E+E QL
Sbjct: 1571 EIERKLAEKDEEMEQAKRNHLRMVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLS 1630
Query: 4894 VANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLRE 5073
ANR+ E + QI+ ++A +A +D+ + +R+ ++AE E+LR
Sbjct: 1631 HANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA 1690
Query: 5074 ANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCEL 5244
E ++RK Q +K++++A ++Q C
Sbjct: 1691 VVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRN 1750
Query: 5245 AIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARA 5424
A +K +KA + +L E+ + E K+++E++ +D + ++ E E A +
Sbjct: 1751 AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKK 1810
Query: 5425 QMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEK 5604
Q+ LEA+V+ LE++L E + + + R+ E+R+ + T Q E++++ + ++L++K
Sbjct: 1811 QLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDK 1870
Query: 5605 SNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
LK + +RQ +EAE++ + +K R VQ E D+
Sbjct: 1871 LQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDE 1905
Score = 146 bits (368), Expect = 7e-33
Identities = 163/824 (19%), Positives = 358/824 (42%), Gaps = 29/824 (3%)
Frame = +1
Query: 3364 LREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRA 3543
++E+ ++A K+E R+E+ EK+ + +K D +Q + +D +A +R
Sbjct: 852 MKEEFGRVKDALEKSEARRKELE---EKMVSLLQEKNDLQLQVQ---AEQDNLADAEERC 905
Query: 3544 IEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIAL 3723
+ I++ K + +V+E+ +++E ++ ++L ++ + + E +++ ++I
Sbjct: 906 DQLIKN---------KIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKRDIDD 956
Query: 3724 LQASRADIDKKRKIHEAHLMEIQANLAESDE-------HKRTL-------IDQLERSRDE 3861
L+ + A ++K++ E + + +A DE K+ L +D L+ D+
Sbjct: 957 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIVKLTKEKKALQEAHQQALDDLQAEEDK 1016
Query: 3862 LDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQ--LEDEKN 4035
++ L + + + E +++ L R+ + R + L+ +
Sbjct: 1017 VNTLTKAKVKLEQQVDDLEGSLEQEKK------------VRMDLERAKRKLEGDLKLTQE 1064
Query: 4036 ALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQL 4215
+++D + + + L L+K+ A AR + E+++ QL++ K+ +E L+++L
Sbjct: 1065 SIMDLENDKQQLDERLKKKDFELN--ALNARIEDEQALGSQLQKKLKELQARIEELEEEL 1122
Query: 4216 EESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKAL 4395
E A+ ++ + + + +ELE+ S LE + + KK E++ + R +++A
Sbjct: 1123 EAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEAT 1182
Query: 4396 LDRDAMSQELRDRETRVLSLLNE-VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNV 4572
L +A + LR + ++ L E +D ++ ++ ++ + + EL D SN + K
Sbjct: 1183 LQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAK 1242
Query: 4573 HELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEA 4752
LEK R+LE ++N+ R + EE + ++ R +L+ N E R + K+
Sbjct: 1243 ANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTEN----GELSRQLDEKEALI 1298
Query: 4753 EEKRRGLL---KQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYX 4923
+ RG L +Q+ DL+ +LE E + K+ + + L +Q E K E
Sbjct: 1299 SQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQ 1358
Query: 4924 XXXXXXXXXXXEYQIE--------CEEARQAKEDIAALLREADRKFRAVEAEREQLREAN 5079
+++ + EE +AK+ +A L++A+ AV A+ L +
Sbjct: 1359 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTK 1418
Query: 5080 EGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKI-AQXXXXXXXXQSNCELAIDK 5256
R Q R+ + ++K+R KI A+ QS E
Sbjct: 1419 H-----RLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE----- 1468
Query: 5257 QRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAA 5436
+Q + ++T+L + +++ ++ +R N++ + +I++L S ++
Sbjct: 1469 --SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSTGKSIH-- 1524
Query: 5437 LEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLK 5616
+++ + QL E E L+ L + E E+ +A+ LE + +K
Sbjct: 1525 ---ELEKIRKQLEAEKLE----------LQSALEEAEASLEHEEGKILRAQ--LEFNQIK 1569
Query: 5617 NRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
+ R+L E ++EM + + H + LDA + E +
Sbjct: 1570 -AEIERKLAEKDEEMEQAKRNHLRMVDSLQTSLDAETRSRNEAL 1612
Score = 134 bits (338), Expect = 2e-29
Identities = 161/831 (19%), Positives = 342/831 (40%), Gaps = 48/831 (5%)
Frame = +1
Query: 3364 LREDMETERNAR--NKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ----DLMSRKDEEV 3525
L E+M ER +R + + R V++++E K +L++ D ++Q M K+
Sbjct: 772 LLEEMRDERLSRIITRIQAQSRGVLSRMEFKK--LLERRDSLLIIQWNIRAFMGVKNWPW 829
Query: 3526 NATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADM 3705
I+ + + E E++ A + + D +E+ + +R +LE++ QE+ D+
Sbjct: 830 MKLYFKIKPLLKSAE--TEKEMATMKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDL 887
Query: 3706 AQEIALLQASRADIDK------KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDEL 3864
++ Q + AD ++ K KI EA + E+ L + +E L + + DE
Sbjct: 888 QLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDEC 947
Query: 3865 DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALL 4044
L R ++ E A +++ K A N+ + L +E L
Sbjct: 948 SELKRDIDDLELTLAKVEKE---------------------KHATENKVKNLTEEMAGL- 985
Query: 4045 DEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEES 4224
+E +K + A Q A + + E+ VN L + + K + V+ L+ LE+
Sbjct: 986 ---DEIIVKLTKEKKALQEAHQQALDDLQAEEDKVNT-LTKAKVKLEQQVDDLEGSLEQE 1041
Query: 4225 EVAKERILQSKKKIQQEL---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKAL 4395
+ + + ++K+K++ +L ++S M+LEN + D ++K FE R+ ++AL
Sbjct: 1042 KKVRMDLERAKRKLEGDLKLTQESIMDLENDK-QQLDERLKKKDFELNALNARIEDEQAL 1100
Query: 4396 LDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVH 4575
+ + ++L++ + R+ L E++ + + +++R L +EL++ ++ G
Sbjct: 1101 GSQ--LQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATS 1158
Query: 4576 ELEKAKRSLEAELNDMRVQMEE----------------------LEDNLQIAEDARLRLE 4689
+ + EAE MR +EE L + + + + +LE
Sbjct: 1159 VQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 1218
Query: 4690 VTNQALKSESDRAISNKD------VEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRK 4851
K E D SN + E+ R L Q+ + ++ E +R + S R
Sbjct: 1219 KEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRA 1278
Query: 4852 KIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA-- 5025
K++ + GEL +QL+ L + + + + EE +AK +A L+ A
Sbjct: 1279 KLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARH 1338
Query: 5026 --DRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIA 5199
D E E E E L +A + + E K++L ++
Sbjct: 1339 DCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ 1398
Query: 5200 QXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKA 5379
+ C + + Q ++E + D+ + ++++ ++ ++K
Sbjct: 1399 DAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQ 1458
Query: 5380 KITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFE 5559
K E +S +S ++ + +L ++ L++ + R + L++ ++D T+Q
Sbjct: 1459 KYEESQSELES-SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLG 1517
Query: 5560 DEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
++ + +++ ++ + L+ L+EAE + E K Q E + +
Sbjct: 1518 STGKSIHELEKIRKQLEAEKLELQSALEEAEASLEHEEGKILRAQLEFNQI 1568
>gi|4557773|ref|NP_000248.1| myosin, heavy polypeptide 7, cardiac
muscle, beta [Homo sapiens]
gi|547966|sp|P12883|MYH7_HUMAN Myosin heavy chain, cardiac muscle
beta isoform (MyHC-beta)
gi|107137|pir||A37102 myosin beta heavy chain, cardiac and skeletal
muscle - human
gi|179508|gb|AAA51837.1| beta-myosin heavy chain [Homo sapiens]
gi|179510|gb|AAA62830.1| beta-myosin heavy chain
Length = 1935
Score = 1154 bits (2985), Expect = 0.0
Identities = 670/1895 (35%), Positives = 1067/1895 (55%), Gaps = 17/1895 (0%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K +VPD + F+ I +V E + + VT+ D V + NPPKFDKIEDM+
Sbjct: 34 KKDVFVPDDKQEFVKAKIVSREGGKVTAE-TEYGKTVTVKEDQVMQQNPPKFDKIEDMAM 92
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LT+L+E +VL+NLKDRY S +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PP
Sbjct: 93 LTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPP 152
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIF+I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A A ++S
Sbjct: 153 HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIA-AIGDRS------ 205
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
K D G LE Q++QANP LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++
Sbjct: 206 -----KKDQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLAS 260
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYL-----LEGVDNYRFLVNR 960
A+IE YLLEKSRV+ Q + ER +HIFYQIL + +K E L +Y F+
Sbjct: 261 ADIETYLLEKSRVIFQLKAERDYHIFYQIL----SNKKPELLDMLLITNNPYDYAFISQG 316
Query: 961 GITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQ 1140
T+ ++DD +E +T N+ ++GF +E +S+ ++ A++ GN++F +++ +QA
Sbjct: 317 ETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPD 376
Query: 1141 DDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLF 1320
K +L+GL +L K PR+KVG E+V K QN +Q +A A+AKA YER+F
Sbjct: 377 GTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMF 436
Query: 1321 KWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFI 1500
W+VTRIN +L+ T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF+
Sbjct: 437 NWMVTRINATLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFV 495
Query: 1501 LEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKT 1680
LEQEEY++EGIEW FIDFG+DLQ IDLIEKPMG++++L+EEC+FPKA D +F KL
Sbjct: 496 LEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLFDN 555
Query: 1681 H-NKHPKFIVP---DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDP 1848
H K F P + ++HF+++HYAG VDY+ WL KN DPLNE VVGL Q S+
Sbjct: 556 HLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLK 615
Query: 1849 FVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVR 2028
++ ++ A +AG A E G + F+TVS LH+E L KLMT LR+T PHFVR
Sbjct: 616 LLSTLF--ANYAG--ADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVR 671
Query: 2029 CIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIP 2208
CIIPN K G +++ LV+ QLRCNGVLEGIRICR+GFPNR+ + +FR RY IL P IP
Sbjct: 672 CIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIP 731
Query: 2209 K-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQ 2385
+ FID ++ K++++LDID N Y+ G +KVFF+ G+L LEE RD +L+ +I QAQ
Sbjct: 732 EGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQ 791
Query: 2386 CRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRA 2565
RG L+R Y N A++ ++NW W +L+ K+KPLL+ + E+ +
Sbjct: 792 SRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAEREKEMAS 851
Query: 2566 KDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTR 2745
+E KE L K E +E E+K+ ++ E+ +Q Q+Q E +N A+ ++ +L
Sbjct: 852 MKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKN 911
Query: 2746 NQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNV 2925
+LE V +M +RL +RK + + +K
Sbjct: 912 KIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHAT 971
Query: 2926 DQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQL 3105
+ + L E++ KAK +LE Q+
Sbjct: 972 ENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQV 1031
Query: 3106 HELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQL 3285
+LE L +E++ + +LE+ KRKL +L+ +++ + + ++L+ +L K+D EL
Sbjct: 1032 DDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALN 1091
Query: 3286 TRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVL 3465
R ++E A + +QK+++++Q I+EL E++E+ER AR K E R ++ +LE++ + L
Sbjct: 1092 ARIEDEQALGSQLQKKLKELQARIEELEEELESERTARAKVEKLRSDLSRELEEI-SERL 1150
Query: 3466 DKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQH 3642
++ AT +Q M++K E E +R +E+ E + K + V EL +QI+
Sbjct: 1151 EEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 1210
Query: 3643 KKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHK 3822
++ + +LEK++++ E D+ + + ++A+++K + E + E ++ E+
Sbjct: 1211 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSV 1270
Query: 3823 RTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANI 4002
L Q + + E L+R +E+E + + R T + K A
Sbjct: 1271 NDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALA 1330
Query: 4003 NRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN 4182
+ + + + L ++ EE +A L++ + A + R K E Q+ EEL +
Sbjct: 1331 HALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAK 1390
Query: 4183 LRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFE 4353
+ + LQ+ E E + + ++K ++Q E+ED +++E A+ +K+Q+ F+
Sbjct: 1391 KKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFD 1450
Query: 4354 SQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQ 4533
+AE + +++ + ++ +E R T + L N + EHLE R ++LQ+E+
Sbjct: 1451 KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEIS 1510
Query: 4534 DSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKS 4713
D GK +HELEK ++ LEAE +++ +EE E +L+ E LR ++ +K+
Sbjct: 1511 DLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKA 1570
Query: 4714 ESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLE 4893
E +R ++ KD E E+ +R L+ + L+ L+ E R ++ A+ +KK+E + E+E QL
Sbjct: 1571 EIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLS 1630
Query: 4894 VANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLRE 5073
ANR+ E + QI+ ++A +A +D+ + +R+ ++AE E+LR
Sbjct: 1631 HANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA 1690
Query: 5074 ANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCEL 5244
E ++RK Q +K++++A ++Q C
Sbjct: 1691 VVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRN 1750
Query: 5245 AIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARA 5424
A +K +KA + +L E+ + E K+++E++ +D + ++ E E A +
Sbjct: 1751 AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKK 1810
Query: 5425 QMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEK 5604
Q+ LEA+V+ LE++L E + + + R+ E+R+ + T Q E++++ + ++L++K
Sbjct: 1811 QLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDK 1870
Query: 5605 SNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
LK + +RQ +EAE++ + +K R VQ E D+
Sbjct: 1871 LQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDE 1905
Score = 151 bits (382), Expect = 2e-34
Identities = 167/829 (20%), Positives = 348/829 (41%), Gaps = 21/829 (2%)
Frame = +1
Query: 3325 QKQMRDMQTTIDELREDMETERNARNKAE-------MTRREVVAQLEKVKGDVLDKVDEA 3483
+K+M M+ L+E +E R + E + ++ Q++ + ++ D +
Sbjct: 846 EKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERC 905
Query: 3484 TMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQL 3663
L + + +V +E + M ++ +K K + EL I+ + +++
Sbjct: 906 DQLIKNKIQLEAKVKEMNERLED-EEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKV 964
Query: 3664 EKQQNQADQERADMAQEIALLQASRADIDKKRK-IHEAHLMEIQANLAESDEHKRTLIDQ 3840
EK+++ + + ++ +E+A L A + K++K + EAH + AE D+ TL
Sbjct: 965 EKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK-VNTLTKA 1023
Query: 3841 LERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQL 4020
+ ++D L E+E+ +++R A L
Sbjct: 1024 KVKLEQQVDDLEGSLEQEKKVRMDLER------------------------AKRKLEGDL 1059
Query: 4021 EDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEH 4200
+ + +++D + + + L L+K+ A AR + E+++ QL++ K+ +E
Sbjct: 1060 KLTQESIMDLENDKQQLDERLKKKDFELN--ALNARIEDEQALGSQLQKKLKELQARIEE 1117
Query: 4201 LQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVA 4380
L+++LE A+ ++ + + + +ELE+ S LE + + KK E++ + R
Sbjct: 1118 LEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRD 1177
Query: 4381 VQKALLDRDAMSQELRDRETRVLSLLNE-VDIMKEHLEESDRVRRSLQQELQDSISNKDD 4557
+++A L +A + LR + ++ L E +D ++ ++ ++ + + EL D SN +
Sbjct: 1178 LEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQ 1237
Query: 4558 FGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISN 4737
K LEK R+LE ++N+ R + EE + ++ R +L+ N E R +
Sbjct: 1238 IIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTEN----GELSRQLDE 1293
Query: 4738 KDVEAEEKRRGLL---KQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRL 4908
K+ + RG L +Q+ DL+ +LE E + K+ + + L +Q E
Sbjct: 1294 KEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEA 1353
Query: 4909 KEEYXXXXXXXXXXXXEYQIE--------CEEARQAKEDIAALLREADRKFRAVEAEREQ 5064
K E +++ + EE +AK+ +A L+EA+ AV A+
Sbjct: 1354 KAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSS 1413
Query: 5065 LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKI-AQXXXXXXXXQSNCE 5241
L + R Q R+ + ++K+R KI A+ QS E
Sbjct: 1414 LEKTKH-----RLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE 1468
Query: 5242 LAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRAR 5421
+Q + ++T+L + +++ ++ +R N++ + +I++L S +
Sbjct: 1469 -------SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGK 1521
Query: 5422 AQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLE 5601
+++ + QL E E L+ L + E E+ +A+ LE
Sbjct: 1522 TIH-----ELEKVRKQLEAEKME----------LQSALEEAEASLEHEEGKILRAQ--LE 1564
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
+ +K + R+L E ++EM + + H V LDA + E +
Sbjct: 1565 FNQIK-AEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEAL 1612
Score = 138 bits (348), Expect = 1e-30
Identities = 166/833 (19%), Positives = 345/833 (40%), Gaps = 50/833 (6%)
Frame = +1
Query: 3364 LREDMETERNAR--NKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ----DLMSRKDEEV 3525
L E+M ER +R + + R V+A++E K +L++ D ++Q M K+
Sbjct: 772 LLEEMRDERLSRIITRIQAQSRGVLARMEYKK--LLERRDSLLVIQWNIRAFMGVKNWPW 829
Query: 3526 NATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADM 3705
I+ + + E E++ A + L + +E+ + +R +LE++ QE+ D+
Sbjct: 830 MKLYFKIKPLLKSAER--EKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDL 887
Query: 3706 AQEIALLQASRADIDK------KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDEL 3864
++ Q + AD ++ K KI EA + E+ L + +E L + + DE
Sbjct: 888 QLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDEC 947
Query: 3865 DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALL 4044
L R ++ E A +++ K A N+ + L +E A L
Sbjct: 948 SELKRDIDDLELTLAKVEKE---------------------KHATENKVKNLTEEM-AGL 985
Query: 4045 DEKEEAEGLRAHLEKEIHAARQGAGEARR--KAEESVNQQLEELRKKNLRDVEHLQKQLE 4218
DE + A L KE A ++ +A +AEE L + + K + V+ L+ LE
Sbjct: 986 DE------IIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLE 1039
Query: 4219 ESEVAKERILQSKKKIQQEL---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQK 4389
+ + + + ++K+K++ +L ++S M+LEN + D ++K FE R+ ++
Sbjct: 1040 QEKKVRMDLERAKRKLEGDLKLTQESIMDLENDK-QQLDERLKKKDFELNALNARIEDEQ 1098
Query: 4390 ALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKN 4569
AL + + ++L++ + R+ L E++ + + +++R L +EL++ ++ G
Sbjct: 1099 ALGSQ--LQKKLKELQARIEELEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGA 1156
Query: 4570 VHELEKAKRSLEAELNDMRVQMEE----------------------LEDNLQIAEDARLR 4683
+ + EAE MR +EE L + + + + +
Sbjct: 1157 TSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQK 1216
Query: 4684 LEVTNQALKSESDRAISNKD------VEAEEKRRGLLKQIRDLENELENEKRGKSGAVSH 4845
LE K E D SN + E+ R L Q+ + ++ E +R + S
Sbjct: 1217 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 1276
Query: 4846 RKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA 5025
R K++ + GEL +QL+ L + + + + EE +AK +A L+ A
Sbjct: 1277 RAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSA 1336
Query: 5026 ----DRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAK 5193
D E E E E L +A + + E K++L +
Sbjct: 1337 RHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1396
Query: 5194 IAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDY 5373
+ + + C + + Q ++E + D+ + ++++ ++ ++
Sbjct: 1397 LQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEW 1456
Query: 5374 KAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQ 5553
K K E +S +S ++ + +L ++ L++ + R + L++ ++D T+Q
Sbjct: 1457 KQKYEESQSELES-SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQ 1515
Query: 5554 FEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ + +++ ++ + L+ L+EAE + E K Q E + +
Sbjct: 1516 LGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQI 1568
Score = 70.5 bits (171), Expect = 5e-10
Identities = 76/395 (19%), Positives = 168/395 (42%), Gaps = 10/395 (2%)
Frame = +1
Query: 4579 LEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEE 4758
L+ A+R E E+ M+ + L++ L+ KSE+ R E EE
Sbjct: 840 LKSAER--EKEMASMKEEFTRLKEALE----------------KSEARRK------ELEE 875
Query: 4759 KRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXX 4938
K LL++ DL+ +++ E+ + A ++ +LE +++ N E+
Sbjct: 876 KMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAE 935
Query: 4939 XXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXX 5118
+ + EC E ++ +D+ L + +++ A E + + L E GL + +
Sbjct: 936 LTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKE 995
Query: 5119 XXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTD 5298
+ E+ ++ + + + E ++++++K ++ LE+
Sbjct: 996 KKALQEAHQQALDDLQAEEDKVNT-LTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRK 1054
Query: 5299 LSMERTLNQKT----EAEKQSLER--SNRDYKAKI----TELESGAQSRARAQMAALEAK 5448
L + L Q++ E +KQ L+ +D++ E E S+ + ++ L+A+
Sbjct: 1055 LEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQAR 1114
Query: 5449 VQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNL 5628
++ LE++L E + + L + L + +++ E+ A E+ +K + + +
Sbjct: 1115 IEELEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKM 1174
Query: 5629 RRQLDEAEDEMSRERTKHRNVQREADDLLDANEQL 5733
RR L+EA + E T ++ AD + + EQ+
Sbjct: 1175 RRDLEEA--TLQHEATAAALRKKHADSVAELGEQI 1207
>gi|12053672|emb|CAC20413.1| beta-myosin heavy chain [Homo sapiens]
Length = 1935
Score = 1153 bits (2982), Expect = 0.0
Identities = 670/1895 (35%), Positives = 1065/1895 (55%), Gaps = 17/1895 (0%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K +VPD + F+ I +V E + + VT+ D V + NPPKFDKIEDM+
Sbjct: 34 KKDVFVPDDKQEFVKAKIVSREGGKVTAE-TEYGKTVTVKEDQVMQQNPPKFDKIEDMAM 92
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LT+L+E +VL+NLKDRY S +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PP
Sbjct: 93 LTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPP 152
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIF+I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A A ++S
Sbjct: 153 HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIA-AIGDRS------ 205
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
K D G LE Q++QANP LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++
Sbjct: 206 -----KKDQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLAS 260
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYL-----LEGVDNYRFLVNR 960
A+IE YLLEKSRV+ Q + ER +HIFYQIL + +K E L +Y F+
Sbjct: 261 ADIETYLLEKSRVIFQLKAERDYHIFYQIL----SNKKPELLDMLLITNNPYDYAFISQG 316
Query: 961 GITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQ 1140
T+ ++DD +E +T N+ ++GF +E +S+ ++ A++ GN++F +++ +QA
Sbjct: 317 ETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPD 376
Query: 1141 DDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLF 1320
K +L+GL +L K PR+KVG E+V K QN +Q +A A+AKA YER+F
Sbjct: 377 GTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMF 436
Query: 1321 KWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFI 1500
W+VTRIN +L+ T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF+
Sbjct: 437 NWMVTRINATLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFV 495
Query: 1501 LEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKT 1680
LEQEEY++EGIEW FIDFG+DLQ IDLIEKPMG++++L+EEC+FPKA D +F KL
Sbjct: 496 LEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLFDN 555
Query: 1681 H-NKHPKFIVP---DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDP 1848
H K F P + ++HF+++HYAG VDY+ WL KN DPLNE VVGL Q S+
Sbjct: 556 HLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLK 615
Query: 1849 FVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVR 2028
++ ++ A +AG A E G + F+TVS LH+E L KLMT LR+T PHFVR
Sbjct: 616 LLSTLF--ANYAG--ADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVR 671
Query: 2029 CIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIP 2208
CIIPN K G +++ LV+ QLRCNGVLEGIRICR+GFPNR+ + +FR RY IL P IP
Sbjct: 672 CIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIP 731
Query: 2209 K-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQ 2385
+ FID ++ K++++LDID N Y+ G +KVFF+ G+L LEE RD +L+ +I QAQ
Sbjct: 732 EGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQ 791
Query: 2386 CRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRA 2565
RG L+R Y N A++ ++NW W +L+ K+KPLL+ + E+ +
Sbjct: 792 SRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAEREKEMAS 851
Query: 2566 KDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTR 2745
+E KE L K E +E E+K+ ++ E+ +Q Q+Q E +N A+ ++ +L
Sbjct: 852 MKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKN 911
Query: 2746 NQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNV 2925
+LE V +M +RL +RK + + +K
Sbjct: 912 KIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHAT 971
Query: 2926 DQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQL 3105
+ + L E++ KAK +LE Q+
Sbjct: 972 ENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQV 1031
Query: 3106 HELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQL 3285
+LE L +E++ + +LE+ KRKL +L+ +++ + + ++L+ +L K+D EL
Sbjct: 1032 DDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALN 1091
Query: 3286 TRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVL 3465
R ++E A + +QK+++++Q I+EL E++E ER AR K E R ++ +LE++ + L
Sbjct: 1092 ARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEI-SERL 1150
Query: 3466 DKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQH 3642
++ AT Q M++K E E +R +E+ E + K + V EL +QI+
Sbjct: 1151 EEAGGATSCQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 1210
Query: 3643 KKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHK 3822
++ + +LEK++++ E D+ + + ++A+++K + E + E ++ E+
Sbjct: 1211 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSV 1270
Query: 3823 RTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANI 4002
L Q + + E L+R +E+E + + R T + K A
Sbjct: 1271 NDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALA 1330
Query: 4003 NRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN 4182
+ + + + L ++ EE +A L++ + A + R K E Q+ EEL +
Sbjct: 1331 HALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAK 1390
Query: 4183 LRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFE 4353
+ + LQ+ E E + + ++K ++Q E+ED +++E A+ +K+Q+ F+
Sbjct: 1391 KKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFD 1450
Query: 4354 SQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQ 4533
+AE + +++ + ++ +E R T + L N + EHLE R ++LQ+E+
Sbjct: 1451 KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEIS 1510
Query: 4534 DSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKS 4713
D GK +HELEK ++ LEAE +++ +EE E +L+ E LR ++ +K+
Sbjct: 1511 DLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKA 1570
Query: 4714 ESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLE 4893
E +R ++ KD E E+ +R L+ + L+ L+ E R ++ A+ +KK+E + E+E QL
Sbjct: 1571 EIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLS 1630
Query: 4894 VANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLRE 5073
ANR+ E + QI+ ++A +A +D+ + +R+ ++AE E+LR
Sbjct: 1631 HANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA 1690
Query: 5074 ANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCEL 5244
E ++RK Q +K++++A ++Q C
Sbjct: 1691 VVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRN 1750
Query: 5245 AIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARA 5424
A +K +KA + +L E+ + E K+++E++ +D + ++ E E A +
Sbjct: 1751 AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKK 1810
Query: 5425 QMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEK 5604
Q+ LEA+V+ LE++L E + + + R+ E+R+ + T Q E++++ + ++L++K
Sbjct: 1811 QLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDK 1870
Query: 5605 SNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
LK + +RQ +EAE++ + +K R VQ E D+
Sbjct: 1871 LQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDE 1905
Score = 151 bits (381), Expect = 2e-34
Identities = 167/829 (20%), Positives = 348/829 (41%), Gaps = 21/829 (2%)
Frame = +1
Query: 3325 QKQMRDMQTTIDELREDMETERNARNKAE-------MTRREVVAQLEKVKGDVLDKVDEA 3483
+K+M M+ L+E +E R + E + ++ Q++ + ++ D +
Sbjct: 846 EKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERC 905
Query: 3484 TMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQL 3663
L + + +V +E + M ++ +K K + EL I+ + +++
Sbjct: 906 DQLIKNKIQLEAKVKEMNERLED-EEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKV 964
Query: 3664 EKQQNQADQERADMAQEIALLQASRADIDKKRK-IHEAHLMEIQANLAESDEHKRTLIDQ 3840
EK+++ + + ++ +E+A L A + K++K + EAH + AE D+ TL
Sbjct: 965 EKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK-VNTLTKA 1023
Query: 3841 LERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQL 4020
+ ++D L E+E+ +++R A L
Sbjct: 1024 KVKLEQQVDDLEGSLEQEKKVRMDLER------------------------AKRKLEGDL 1059
Query: 4021 EDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEH 4200
+ + +++D + + + L L+K+ A AR + E+++ QL++ K+ +E
Sbjct: 1060 KLTQESIMDLENDKQQLDERLKKKDFELN--ALNARIEDEQALGSQLQKKLKELQARIEE 1117
Query: 4201 LQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVA 4380
L+++LE A+ ++ + + + +ELE+ S LE + + KK E++ + R
Sbjct: 1118 LEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSCQIEMNKKREAEFQKMRRD 1177
Query: 4381 VQKALLDRDAMSQELRDRETRVLSLLNE-VDIMKEHLEESDRVRRSLQQELQDSISNKDD 4557
+++A L +A + LR + ++ L E +D ++ ++ ++ + + EL D SN +
Sbjct: 1178 LEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQ 1237
Query: 4558 FGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISN 4737
K LEK R+LE ++N+ R + EE + ++ R +L+ N E R +
Sbjct: 1238 IIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTEN----GELSRQLDE 1293
Query: 4738 KDVEAEEKRRGLL---KQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRL 4908
K+ + RG L +Q+ DL+ +LE E + K+ + + L +Q E
Sbjct: 1294 KEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEA 1353
Query: 4909 KEEYXXXXXXXXXXXXEYQIE--------CEEARQAKEDIAALLREADRKFRAVEAEREQ 5064
K E +++ + EE +AK+ +A L+EA+ AV A+
Sbjct: 1354 KAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSS 1413
Query: 5065 LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKI-AQXXXXXXXXQSNCE 5241
L + R Q R+ + ++K+R KI A+ QS E
Sbjct: 1414 LEKTKH-----RLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE 1468
Query: 5242 LAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRAR 5421
+Q + ++T+L + +++ ++ +R N++ + +I++L S +
Sbjct: 1469 -------SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGK 1521
Query: 5422 AQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLE 5601
+++ + QL E E L+ L + E E+ +A+ LE
Sbjct: 1522 TIH-----ELEKVRKQLEAEKME----------LQSALEEAEASLEHEEGKILRAQ--LE 1564
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
+ +K + R+L E ++EM + + H V LDA + E +
Sbjct: 1565 FNQIK-AEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEAL 1612
Score = 138 bits (347), Expect = 2e-30
Identities = 166/833 (19%), Positives = 345/833 (40%), Gaps = 50/833 (6%)
Frame = +1
Query: 3364 LREDMETERNAR--NKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ----DLMSRKDEEV 3525
L E+M ER +R + + R V+A++E K +L++ D ++Q M K+
Sbjct: 772 LLEEMRDERLSRIITRIQAQSRGVLARMEYKK--LLERRDSLLVIQWNIRAFMGVKNWPW 829
Query: 3526 NATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADM 3705
I+ + + E E++ A + L + +E+ + +R +LE++ QE+ D+
Sbjct: 830 MKLYFKIKPLLKSAER--EKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDL 887
Query: 3706 AQEIALLQASRADIDK------KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDEL 3864
++ Q + AD ++ K KI EA + E+ L + +E L + + DE
Sbjct: 888 QLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDEC 947
Query: 3865 DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALL 4044
L R ++ E A +++ K A N+ + L +E A L
Sbjct: 948 SELKRDIDDLELTLAKVEKE---------------------KHATENKVKNLTEEM-AGL 985
Query: 4045 DEKEEAEGLRAHLEKEIHAARQGAGEARR--KAEESVNQQLEELRKKNLRDVEHLQKQLE 4218
DE + A L KE A ++ +A +AEE L + + K + V+ L+ LE
Sbjct: 986 DE------IIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLE 1039
Query: 4219 ESEVAKERILQSKKKIQQEL---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQK 4389
+ + + + ++K+K++ +L ++S M+LEN + D ++K FE R+ ++
Sbjct: 1040 QEKKVRMDLERAKRKLEGDLKLTQESIMDLENDK-QQLDERLKKKDFELNALNARIEDEQ 1098
Query: 4390 ALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKN 4569
AL + + ++L++ + R+ L E++ + + +++R L +EL++ ++ G
Sbjct: 1099 ALGSQ--LQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGA 1156
Query: 4570 VHELEKAKRSLEAELNDMRVQMEE----------------------LEDNLQIAEDARLR 4683
+ + EAE MR +EE L + + + + +
Sbjct: 1157 TSCQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQK 1216
Query: 4684 LEVTNQALKSESDRAISNKD------VEAEEKRRGLLKQIRDLENELENEKRGKSGAVSH 4845
LE K E D SN + E+ R L Q+ + ++ E +R + S
Sbjct: 1217 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 1276
Query: 4846 RKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA 5025
R K++ + GEL +QL+ L + + + + EE +AK +A L+ A
Sbjct: 1277 RAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSA 1336
Query: 5026 ----DRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAK 5193
D E E E E L +A + + E K++L +
Sbjct: 1337 RHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1396
Query: 5194 IAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDY 5373
+ + + C + + Q ++E + D+ + ++++ ++ ++
Sbjct: 1397 LQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEW 1456
Query: 5374 KAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQ 5553
K K E +S +S ++ + +L ++ L++ + R + L++ ++D T+Q
Sbjct: 1457 KQKYEESQSELES-SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQ 1515
Query: 5554 FEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ + +++ ++ + L+ L+EAE + E K Q E + +
Sbjct: 1516 LGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQI 1568
Score = 70.9 bits (172), Expect = 4e-10
Identities = 76/395 (19%), Positives = 168/395 (42%), Gaps = 10/395 (2%)
Frame = +1
Query: 4579 LEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEE 4758
L+ A+R E E+ M+ + L++ L+ KSE+ R E EE
Sbjct: 840 LKSAER--EKEMASMKEEFTRLKEALE----------------KSEARRK------ELEE 875
Query: 4759 KRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXX 4938
K LL++ DL+ +++ E+ + A ++ +LE +++ N E+
Sbjct: 876 KMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAE 935
Query: 4939 XXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXX 5118
+ + EC E ++ +D+ L + +++ A E + + L E GL + +
Sbjct: 936 LTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKE 995
Query: 5119 XXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTD 5298
+ E+ ++ + + + E ++++++K ++ LE+
Sbjct: 996 KKALQEAHQQALDDLQAEEDKVNT-LTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRK 1054
Query: 5299 LSMERTLNQKT----EAEKQSLER--SNRDYKAKI----TELESGAQSRARAQMAALEAK 5448
L + L Q++ E +KQ L+ +D++ E E S+ + ++ L+A+
Sbjct: 1055 LEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQAR 1114
Query: 5449 VQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNL 5628
++ LE++L E + + L + L + +++ E+ A E+ +K + + +
Sbjct: 1115 IEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSCQIEMNKKREAEFQKM 1174
Query: 5629 RRQLDEAEDEMSRERTKHRNVQREADDLLDANEQL 5733
RR L+EA + E T ++ AD + + EQ+
Sbjct: 1175 RRDLEEA--TLQHEATAAALRKKHADSVAELGEQI 1207
>gi|12060489|dbj|BAB20630.1| myosin heavy chain slow isoform [Sus
scrofa]
Length = 1935
Score = 1153 bits (2982), Expect = 0.0
Identities = 670/1896 (35%), Positives = 1061/1896 (55%), Gaps = 18/1896 (0%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K +VPD E F+ I +V E + + VT+ D V + NPPKFDKIEDM+
Sbjct: 34 KKDVYVPDDKEEFVKAKILSREGGKVTAE-TEHGKTVTVKEDQVLQQNPPKFDKIEDMAM 92
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LT+L+E +VL+NLK+RY S +IYTYSGLFCV INPYK LP+Y+ +++ ++GKKR E PP
Sbjct: 93 LTFLHEPAVLYNLKERYASWMIYTYSGLFCVTINPYKWLPVYNAEVVAAYRGKKRSEAPP 152
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAG-ATRNKSLNAAA 612
HIF+I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A R+K
Sbjct: 153 HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKEQTPG 212
Query: 613 QQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYIS 792
+ G LE Q++QANP LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++
Sbjct: 213 K-------------GTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLA 259
Query: 793 GANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYL-----LEGVDNYRFLVN 957
A+IE YLLEKSRV+ Q + ER +HIFYQIL + +K E L +Y F+
Sbjct: 260 SADIETYLLEKSRVIFQLKAERDYHIFYQIL----SNKKPELLDMLLITNNPYDYAFISQ 315
Query: 958 RGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAML 1137
T+ ++DD +E +T N+ ++GF +E +S+ ++ A++ GN++F +++ +QA
Sbjct: 316 GETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEP 375
Query: 1138 QDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERL 1317
K +L+GL +L K PR+KVG E+V K QN +Q +A A+AKA YE++
Sbjct: 376 DGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVMYATGALAKAVYEKM 435
Query: 1318 FKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMF 1497
F W+VTRIN +L+ T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF
Sbjct: 436 FNWMVTRINTTLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMF 494
Query: 1498 ILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQK 1677
+LEQEEY++EGIEW+FIDFG+DLQ IDLIEKPMG++++L+EEC+FPKA D +F KL
Sbjct: 495 VLEQEEYKKEGIEWEFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLYD 554
Query: 1678 TH-NKHPKFIVP---DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTD 1845
H K F P R ++HFA++HYAG VDY+ WL KN DPLNE VV L + S+
Sbjct: 555 NHLGKSNNFQKPRNIKGRPEAHFALIHYAGTVDYNIIGWLQKNKDPLNETVVDLYKKSSL 614
Query: 1846 PFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFV 2025
++ ++ A +AG A E G + F+TVS LH+E L KLMT LR+T PHFV
Sbjct: 615 KLLSNLF--ANYAG--ADTPVEKGKGKAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFV 670
Query: 2026 RCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVI 2205
RCIIPN K G I++ LV+ QLRCNGVLEGIRICR+GFPNR+ + +FR RY IL P I
Sbjct: 671 RCIIPNETKSPGVIDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAI 730
Query: 2206 PK-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQA 2382
P+ FID ++ K++ +LDID N Y+ G +KVFF+ G+L LEE RD +L+ +I QA
Sbjct: 731 PEGQFIDSRKGAEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQA 790
Query: 2383 QCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIR 2562
Q RG LSR + N A++ ++NW W +L+ K+KPLL+ T+ E+
Sbjct: 791 QSRGVLSRMEFKKLLERRDSLLIIQWNIRAFMSVKNWPWMKLYFKIKPLLKSAETEKEMA 850
Query: 2563 AKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQT 2742
+E KE L K E +E E+K+ ++ E+ +Q Q+Q E +N A+ ++ +L
Sbjct: 851 TMKEEFGRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIK 910
Query: 2743 RNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTN 2922
+LE V +M +RL +RK + + +K
Sbjct: 911 NKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHA 970
Query: 2923 VDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQ 3102
+ + L E++ KAK +LE
Sbjct: 971 TENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQH 1030
Query: 3103 LHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQ 3282
+ +LE L +E++ + +LE+ KRKL +L+ +++ + + ++L+ +L K+D EL
Sbjct: 1031 VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNAL 1090
Query: 3283 LTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDV 3462
R ++E A + +QK+++++Q I+EL E++E ER AR K E R ++ +LE++ +
Sbjct: 1091 NARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEI-SER 1149
Query: 3463 LDKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQ 3639
L++ AT +Q M++K E E +R +E+ E + K + V EL +QI+
Sbjct: 1150 LEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDN 1209
Query: 3640 HKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEH 3819
++ + +LEK++++ E D+ + + ++A+++K + E + E ++ E+
Sbjct: 1210 LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRS 1269
Query: 3820 KRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIAN 3999
L Q + + E L+R +E+E + + R T + K A
Sbjct: 1270 VNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNAL 1329
Query: 4000 INRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKK 4179
+ + + + L ++ EE +A L++ + A + R K E Q+ EEL +
Sbjct: 1330 AHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 1389
Query: 4180 NLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKF 4350
+ + LQ E E + + ++K ++Q E+ED +++E A+ +K+Q+ F
Sbjct: 1390 KKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNF 1449
Query: 4351 ESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQEL 4530
+ +AE + +++ + ++ +E R T + L N + EHLE R ++LQ+E+
Sbjct: 1450 DKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEI 1509
Query: 4531 QDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALK 4710
D GK +HELEK ++ LEAE +++ +EE E +L+ E LR ++ +K
Sbjct: 1510 SDLTEQLGSSGKTIHELEKVRKQLEAEKLELQSALEEAEASLEHEEGKILRAQLEFNQIK 1569
Query: 4711 SESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
+E +R ++ KD E E+ +R L+ + L+ L+ E R ++ A+ +KK+E + E+E QL
Sbjct: 1570 AEMERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQL 1629
Query: 4891 EVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLR 5070
ANR+ E + QI+ ++A +A +D+ + +R+ ++AE E+LR
Sbjct: 1630 SHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELR 1689
Query: 5071 EANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCE 5241
E ++RK Q +K+++EA ++Q C
Sbjct: 1690 AVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMEADLSQLQTEVEEAVQECR 1749
Query: 5242 LAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRAR 5421
A +K +KA + +L E+ + E K+++E++ +D + ++ E E A +
Sbjct: 1750 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGK 1809
Query: 5422 AQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLE 5601
Q+ LEA+V+ LE++L E + + + R+ E+R+ + T Q E++++ + ++L++
Sbjct: 1810 KQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVD 1869
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
K LK + +RQ +EAE++ + +K R VQ E D+
Sbjct: 1870 KLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDE 1905
Score = 148 bits (373), Expect = 2e-33
Identities = 173/832 (20%), Positives = 349/832 (41%), Gaps = 24/832 (2%)
Frame = +1
Query: 3325 QKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVD-EATMLQDL 3501
+K+M M+ L+E +E R + E E + L + K D+ +V E L D
Sbjct: 846 EKEMATMKEEFGRLKEALEKSEARRKELE----EKMVSLLQEKNDLQLQVQAEQDNLADA 901
Query: 3502 MSRKDEEVN-------ATKRAIEQIQ--HTMEGKIEEQKAKFSRQVEELHDQIEQHKKQR 3654
R D+ + K E+++ M ++ +K K + EL I+ +
Sbjct: 902 EERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTL 961
Query: 3655 SQLEKQQNQADQERADMAQEIALLQASRADIDKKRK-IHEAHLMEIQANLAESDEHKRTL 3831
+++EK+++ + + ++ +E+A L A + K++K + EAH + AE D+ TL
Sbjct: 962 AKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK-VNTL 1020
Query: 3832 IDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRA 4011
+ +D L E+E+ +++R A
Sbjct: 1021 TKAKVKLEQHVDDLEGSLEQEKKVRMDLER------------------------AKRKLE 1056
Query: 4012 RQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRD 4191
L+ + +++D + + + L L+K+ A AR + E+++ QL++ K+
Sbjct: 1057 GDLKLTQESIMDLENDKQQLDERLKKKDFELN--ALNARIEDEQALGSQLQKKLKELQAR 1114
Query: 4192 VEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEE 4371
+E L+++LE A+ ++ + + + +ELE+ S LE + + KK E++ +
Sbjct: 1115 IEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKM 1174
Query: 4372 RVAVQKALLDRDAMSQELRDRETRVLSLLNE-VDIMKEHLEESDRVRRSLQQELQDSISN 4548
R +++A L +A + LR + ++ L E +D ++ ++ ++ + + EL D SN
Sbjct: 1175 RRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 1234
Query: 4549 KDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRA 4728
+ K LEK R+LE ++N+ R + EE + ++ R +L+ N E R
Sbjct: 1235 MEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTEN----GELSRQ 1290
Query: 4729 ISNKDVEAEEKRRGLL---KQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
+ K+ + RG L +Q+ DL+ +LE E + K+ + + L +Q E
Sbjct: 1291 LDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEE 1350
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIE--------CEEARQAKEDIAALLREADRKFRAVEAE 5055
K E +++ + EE +AK+ +A L++A+ AV A+
Sbjct: 1351 TEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAK 1410
Query: 5056 REQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKI-AQXXXXXXXXQS 5232
L + R Q R+ + ++K+R KI A+ QS
Sbjct: 1411 CSSLEKTKH-----RLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQS 1465
Query: 5233 NCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQS 5412
E +Q + ++T+L + +++ ++ +R N++ + +I++L S
Sbjct: 1466 ELE-------SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGS 1518
Query: 5413 RARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKE 5592
+ +++ + QL E E L+ L + E E+ +A+
Sbjct: 1519 SGKTIH-----ELEKVRKQLEAEKLE----------LQSALEEAEASLEHEEGKILRAQ- 1562
Query: 5593 LLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
LE + +K + R+L E ++EM + + H V LDA + E +
Sbjct: 1563 -LEFNQIK-AEMERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEAL 1612
Score = 136 bits (343), Expect = 5e-30
Identities = 166/833 (19%), Positives = 345/833 (40%), Gaps = 50/833 (6%)
Frame = +1
Query: 3364 LREDMETERNAR--NKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ----DLMSRKDEEV 3525
L E+M ER +R + + R V++++E K +L++ D ++Q MS K+
Sbjct: 772 LLEEMRDERLSRIITRIQAQSRGVLSRMEFKK--LLERRDSLLIIQWNIRAFMSVKNWPW 829
Query: 3526 NATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADM 3705
I+ + + E E++ A + L + +E+ + +R +LE++ QE+ D+
Sbjct: 830 MKLYFKIKPLLKSAE--TEKEMATMKEEFGRLKEALEKSEARRKELEEKMVSLLQEKNDL 887
Query: 3706 AQEIALLQASRADIDK------KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDEL 3864
++ Q + AD ++ K KI EA + E+ L + +E L + + DE
Sbjct: 888 QLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDEC 947
Query: 3865 DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALL 4044
L R ++ E A +++ K A N+ + L +E A L
Sbjct: 948 SELKRDIDDLELTLAKVEKE---------------------KHATENKVKNLTEEM-AGL 985
Query: 4045 DEKEEAEGLRAHLEKEIHAARQGAGEARR--KAEESVNQQLEELRKKNLRDVEHLQKQLE 4218
DE + A L KE A ++ +A +AEE L + + K + V+ L+ LE
Sbjct: 986 DE------IIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQHVDDLEGSLE 1039
Query: 4219 ESEVAKERILQSKKKIQQEL---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQK 4389
+ + + + ++K+K++ +L ++S M+LEN + D ++K FE R+ ++
Sbjct: 1040 QEKKVRMDLERAKRKLEGDLKLTQESIMDLENDK-QQLDERLKKKDFELNALNARIEDEQ 1098
Query: 4390 ALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKN 4569
AL + + ++L++ + R+ L E++ + + +++R L +EL++ ++ G
Sbjct: 1099 ALGSQ--LQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGA 1156
Query: 4570 VHELEKAKRSLEAELNDMRVQMEE----------------------LEDNLQIAEDARLR 4683
+ + EAE MR +EE L + + + + +
Sbjct: 1157 TSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQK 1216
Query: 4684 LEVTNQALKSESDRAISNKD------VEAEEKRRGLLKQIRDLENELENEKRGKSGAVSH 4845
LE K E D SN + E+ R L Q+ + ++ E +R + S
Sbjct: 1217 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 1276
Query: 4846 RKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA 5025
R K++ + GEL +QL+ L + + + + EE +AK +A L+ A
Sbjct: 1277 RAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSA 1336
Query: 5026 ----DRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAK 5193
D E E E E L +A + + E K++L +
Sbjct: 1337 RHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1396
Query: 5194 IAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDY 5373
+ + C + + Q ++E + D+ + ++++ ++ ++
Sbjct: 1397 LQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEW 1456
Query: 5374 KAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQ 5553
K K E +S +S ++ + +L ++ L++ + R + L++ ++D T+Q
Sbjct: 1457 KQKYEESQSELES-SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQ 1515
Query: 5554 FEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ + +++ ++ + L+ L+EAE + E K Q E + +
Sbjct: 1516 LGSSGKTIHELEKVRKQLEAEKLELQSALEEAEASLEHEEGKILRAQLEFNQI 1568
Score = 72.4 bits (176), Expect = 1e-10
Identities = 101/474 (21%), Positives = 191/474 (39%), Gaps = 36/474 (7%)
Frame = +1
Query: 4429 DRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEA 4608
+ E + ++ E +KE LE+S+ R+ ELE+ SL
Sbjct: 844 ETEKEMATMKEEFGRLKEALEKSEARRK---------------------ELEEKMVSLLQ 882
Query: 4609 ELNDMRVQMEELEDNLQIAE---DARLRLEVTNQA-LKSESDRAISNKDVEAE--EKRRG 4770
E ND+++Q++ +DNL AE D ++ ++ +A +K ++R +++ AE K+R
Sbjct: 883 EKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRK 942
Query: 4771 LLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL----EVANRLKEEYXXXXXX 4938
L + +L+ ++++ + + + EN++ L +++ E+ +L +E
Sbjct: 943 LEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKE------- 995
Query: 4939 XXXXXXEYQIECEEARQAKEDIAALLREADRKFRA----VEAEREQLREANEGLMQARKQ 5106
E + + QA+ED L +A K +E EQ ++ L +A+++
Sbjct: 996 -KKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQHVDDLEGSLEQEKKVRMDLERAKRK 1054
Query: 5107 XXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRK---AQVQ 5277
+ RL+ K + + L Q+K Q +
Sbjct: 1055 LEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQAR 1114
Query: 5278 LEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQY 5457
+E++ +L ERT K E + L R + ++ E GA S EA+ Q
Sbjct: 1115 IEELEEELEAERTARAKVEKLRSDLSRELEEISERLEE-AGGATSVQIEMNKKREAEFQK 1173
Query: 5458 LEDQLNVEGQEKTAANRA-ARRLEKRLNDTTQQFEDEKRANEQAKELLEK---------- 5604
+ L +E T + A A L K+ D+ + ++ ++ K+ LEK
Sbjct: 1174 MRRDL----EEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELD 1229
Query: 5605 ---SNLK-----NRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
SN++ NL + ED+M+ R+K QR +DL +L E
Sbjct: 1230 DVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTE 1283
>gi|41386711|ref|NP_777152.1| myosin, heavy polypeptide 7, cardiac
muscle, beta [Bos taurus]
gi|13560273|dbj|BAB40922.1| myosin heavy chain slow [Bos taurus]
Length = 1935
Score = 1152 bits (2980), Expect = 0.0
Identities = 671/1896 (35%), Positives = 1062/1896 (55%), Gaps = 18/1896 (0%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K +VPD E F+ +I +V E + + VT+ D V + NPPKFDKIEDM+
Sbjct: 34 KKDVFVPDDKEEFVKATILSREGGKVTAE-TEHGKTVTVKEDQVLQQNPPKFDKIEDMAM 92
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LT+L+E +VL+NLK+RY S +IYTYSGLFCV INPYK LP+Y+ +++ ++GKKR E PP
Sbjct: 93 LTFLHEPAVLYNLKERYASWMIYTYSGLFCVTINPYKWLPVYNAEVVAAYRGKKRSEAPP 152
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAG-ATRNKSLNAAA 612
HIF+I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A R+K A
Sbjct: 153 HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKEQATG 212
Query: 613 QQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYIS 792
+ G LE Q++QANP LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++
Sbjct: 213 K-------------GTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLA 259
Query: 793 GANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYL-----LEGVDNYRFLVN 957
A+IE YLLEKSRV+ Q + ER +HIFYQIL + +K E L +Y F+
Sbjct: 260 SADIETYLLEKSRVIFQLKAERDYHIFYQIL----SNKKPELLDMLLITNNPYDYAFISQ 315
Query: 958 RGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAML 1137
T+ ++DD +E +T N+ ++GF +E +S+ ++ A++ GN++F +++ +QA
Sbjct: 316 GETTVASIDDAEELMATDNAFDVLGFTTEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEP 375
Query: 1138 QDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERL 1317
K +L+GL +L K PR+KVG E+V K QN +Q +A A+AKA YER+
Sbjct: 376 DGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVVYAKGALAKAVYERM 435
Query: 1318 FKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMF 1497
F W+VTRIN +L+ T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF
Sbjct: 436 FNWMVTRINATLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMF 494
Query: 1498 ILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQK 1677
+LEQEEY++EGIEW+FIDFG+DLQ IDLIEKPMG++++L+EEC+FPKA D +F KL
Sbjct: 495 VLEQEEYKKEGIEWEFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLFD 554
Query: 1678 TH-NKHPKFIVP---DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTD 1845
H K F P + ++HF+++HYAG VDY+ WL KN DPLNE VV L + S+
Sbjct: 555 NHLGKSSNFQKPRNIKGKPEAHFSLIHYAGTVDYNIIGWLQKNKDPLNETVVDLYKKSSL 614
Query: 1846 PFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFV 2025
++ ++ A +AG E G + F+TVS LH+E L KLMT LR+T PHFV
Sbjct: 615 KMLSSLF--ANYAGFDTP--IEKGKGKAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFV 670
Query: 2026 RCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVI 2205
RCIIPN K G I++ LV+ QLRCNGVLEGIRICR+GFPNR+ + +FR RY IL P I
Sbjct: 671 RCIIPNETKSPGVIDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAI 730
Query: 2206 PK-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQA 2382
P+ FID ++ K++ +LDID N Y+ G +KVFF+ G+L LEE RD +L+ +I QA
Sbjct: 731 PEGQFIDSRKGAEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQA 790
Query: 2383 QCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIR 2562
Q RG LSR + N A++ ++NW W +L+ K+KPLL+ T+ EI
Sbjct: 791 QSRGVLSRMEFKKLLERRDSLLIIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEIA 850
Query: 2563 AKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQT 2742
+E KE L K E +E E+K+ ++ E+ +Q Q+Q E +N A+ ++ +L
Sbjct: 851 LMKEEFGRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIK 910
Query: 2743 RNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTN 2922
+LE V +M +RL +RK + + +K
Sbjct: 911 NKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHA 970
Query: 2923 VDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQ 3102
+ + L E++ KAK +LE
Sbjct: 971 TENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQH 1030
Query: 3103 LHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQ 3282
+ +LE L +E++ + +LE+ KRKL +L+ +++ + + ++L+ +L K+D EL
Sbjct: 1031 VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNAL 1090
Query: 3283 LTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDV 3462
R ++E A + +QK+++++Q I+EL E++E ER AR K E R ++ +LE++ +
Sbjct: 1091 NARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEI-SER 1149
Query: 3463 LDKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQ 3639
L++ AT +Q M++K E E +R +E+ E + K + V EL +QI+
Sbjct: 1150 LEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELSEQIDN 1209
Query: 3640 HKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEH 3819
++ + +LEK++++ E D+ + + ++A+++K + E + E ++ E+
Sbjct: 1210 LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRS 1269
Query: 3820 KRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIAN 3999
L Q + + E L+R +E+E + + R T + K A
Sbjct: 1270 VNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNAL 1329
Query: 4000 INRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKK 4179
+ + + + L ++ EE +A L++ + A + R K E Q+ EEL +
Sbjct: 1330 AHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 1389
Query: 4180 NLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKF 4350
+ + LQ E E + + ++K ++Q E+ED +++E A+ +K+Q+ F
Sbjct: 1390 KKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNF 1449
Query: 4351 ESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQEL 4530
+ +AE + +++ + ++ +E R T + L N + EHLE R ++LQ+E+
Sbjct: 1450 DKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEI 1509
Query: 4531 QDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALK 4710
D GK +HELEK ++ LEAE +++ +EE E +L+ E LR ++ +K
Sbjct: 1510 SDLTEQLGSSGKTIHELEKVRKQLEAEKLELQSALEEAEASLEQEEGKILRAQLEFNQIK 1569
Query: 4711 SESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
+E +R ++ KD E E+ +R L+ + L+ L+ E R ++ A+ +KK+E + E+E QL
Sbjct: 1570 AEMERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQL 1629
Query: 4891 EVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLR 5070
ANRL E + QI+ ++A +A +D+ + +R+ ++AE E+LR
Sbjct: 1630 SHANRLAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELR 1689
Query: 5071 EANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCE 5241
E ++RK Q +K+++EA ++Q C
Sbjct: 1690 AVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMEADLSQLQTEVEEAVQECR 1749
Query: 5242 LAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRAR 5421
A +K +KA + +L E+ + E K+++E++ +D + ++ E E A +
Sbjct: 1750 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGK 1809
Query: 5422 AQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLE 5601
Q+ LEA+V+ LE++L E + + + R+ E+R+ + T Q E++++ + ++L++
Sbjct: 1810 KQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVD 1869
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
K LK + +RQ +EAE++ + +K R VQ E D+
Sbjct: 1870 KLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDE 1905
Score = 147 bits (372), Expect = 2e-33
Identities = 179/874 (20%), Positives = 367/874 (41%), Gaps = 18/874 (2%)
Frame = +1
Query: 3181 AELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTID 3360
AE E + E+ G+++E + R +EL+ ++ V+L+Q++ +
Sbjct: 843 AETEKEIALMKEEFGRLKEALEKSEARRKELEEKM---------VSLLQEK--------N 885
Query: 3361 ELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT-MLQDLMSRKDEEVNATK 3537
+L+ ++ E++ AE E QL K K + KV E T L+D +EE+NA
Sbjct: 886 DLQLQVQAEQDNLADAE----ERCDQLIKNKIQLEAKVKEMTERLED-----EEEMNAEL 936
Query: 3538 RAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEI 3717
A ++ K+E++ ++ R +++L + + +K++ E + +E A + + I
Sbjct: 937 TAKKR-------KLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 989
Query: 3718 ALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEE 3897
A L +K+ + EAH + AE D+ TL + +D L E+E+
Sbjct: 990 AKLTK------EKKALQEAHQQALDDLQAEEDK-VNTLTKAKVKLEQHVDDLEGSLEQEK 1042
Query: 3898 HAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRA 4077
+++R A L+ + +++D + + + L
Sbjct: 1043 KVRMDLER------------------------AKRKLEGDLKLTQESIMDLENDKQQLDE 1078
Query: 4078 HLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSK 4257
L+K+ A AR + E+++ QL++ K+ +E L+++LE A+ ++ + +
Sbjct: 1079 RLKKKDFELN--ALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLR 1136
Query: 4258 KKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRE 4437
+ +ELE+ S LE + + KK E++ + R +++A L +A + LR +
Sbjct: 1137 SDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKH 1196
Query: 4438 T-RVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAEL 4614
V L ++D ++ ++ ++ + + EL D SN + K LEK R+LE ++
Sbjct: 1197 ADSVAELSEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQM 1256
Query: 4615 NDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLL---KQI 4785
N+ R + EE + ++ R +L+ N E R + K+ + RG L +Q+
Sbjct: 1257 NEHRSKAEETQRSVNDLTSQRAKLQTEN----GELSRQLDEKEALISQLTRGKLTYTQQL 1312
Query: 4786 RDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQ 4965
DL+ +LE E + K+ + + L +Q E K E +++
Sbjct: 1313 EDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWR 1372
Query: 4966 IE--------CEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXX 5121
+ EE +AK+ +A L++A+ AV A+ L + R Q
Sbjct: 1373 TKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKH-----RLQNEIED 1427
Query: 5122 XXXXXXRAKGGGISSEEKRRLEAKI-AQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTD 5298
R+ + ++K+R KI A+ QS E +Q + ++T+
Sbjct: 1428 LMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE-------SSQKEARSLSTE 1480
Query: 5299 LSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNV 5478
L + +++ ++ +R N++ + +I++L +QL
Sbjct: 1481 LFKLKNAYEESLEHLETFKRENKNLQEEISDLT----------------------EQLGS 1518
Query: 5479 EGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLR----RQLDE 5646
G+ + ++LE + E+ + + EQ + + ++ L+ ++ R+L E
Sbjct: 1519 SGKTIHELEKVRKQLEAEKLELQSALEEAEASLEQEEGKILRAQLEFNQIKAEMERKLAE 1578
Query: 5647 AEDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
++EM + + H V LDA + E +
Sbjct: 1579 KDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEAL 1612
Score = 135 bits (339), Expect = 2e-29
Identities = 165/833 (19%), Positives = 345/833 (40%), Gaps = 50/833 (6%)
Frame = +1
Query: 3364 LREDMETERNAR--NKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ----DLMSRKDEEV 3525
L E+M ER +R + + R V++++E K +L++ D ++Q M K+
Sbjct: 772 LLEEMRDERLSRIITRIQAQSRGVLSRMEFKK--LLERRDSLLIIQWNIRAFMGVKNWPW 829
Query: 3526 NATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADM 3705
I+ + + E E++ A + L + +E+ + +R +LE++ QE+ D+
Sbjct: 830 MKLYFKIKPLLKSAE--TEKEIALMKEEFGRLKEALEKSEARRKELEEKMVSLLQEKNDL 887
Query: 3706 AQEIALLQASRADIDK------KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDEL 3864
++ Q + AD ++ K KI EA + E+ L + +E L + + DE
Sbjct: 888 QLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDEC 947
Query: 3865 DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALL 4044
L R ++ E A +++ K A N+ + L +E A L
Sbjct: 948 SELKRDIDDLELTLAKVEKE---------------------KHATENKVKNLTEEM-AGL 985
Query: 4045 DEKEEAEGLRAHLEKEIHAARQGAGEARR--KAEESVNQQLEELRKKNLRDVEHLQKQLE 4218
DE + A L KE A ++ +A +AEE L + + K + V+ L+ LE
Sbjct: 986 DE------IIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQHVDDLEGSLE 1039
Query: 4219 ESEVAKERILQSKKKIQQEL---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQK 4389
+ + + + ++K+K++ +L ++S M+LEN + D ++K FE R+ ++
Sbjct: 1040 QEKKVRMDLERAKRKLEGDLKLTQESIMDLENDK-QQLDERLKKKDFELNALNARIEDEQ 1098
Query: 4390 ALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKN 4569
AL + + ++L++ + R+ L E++ + + +++R L +EL++ ++ G
Sbjct: 1099 ALGSQ--LQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGA 1156
Query: 4570 VHELEKAKRSLEAELNDMRVQMEE----------------------LEDNLQIAEDARLR 4683
+ + EAE MR +EE L + + + + +
Sbjct: 1157 TSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELSEQIDNLQRVKQK 1216
Query: 4684 LEVTNQALKSESDRAISNKD------VEAEEKRRGLLKQIRDLENELENEKRGKSGAVSH 4845
LE K E D SN + E+ R L Q+ + ++ E +R + S
Sbjct: 1217 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 1276
Query: 4846 RKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA 5025
R K++ + GEL +QL+ L + + + + EE +AK +A L+ A
Sbjct: 1277 RAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSA 1336
Query: 5026 ----DRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAK 5193
D E E E E L +A + + E K++L +
Sbjct: 1337 RHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1396
Query: 5194 IAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDY 5373
+ + C + + Q ++E + D+ + ++++ ++ ++
Sbjct: 1397 LQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEW 1456
Query: 5374 KAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQ 5553
K K E +S +S ++ + +L ++ L++ + R + L++ ++D T+Q
Sbjct: 1457 KQKYEESQSELES-SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQ 1515
Query: 5554 FEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ + +++ ++ + L+ L+EAE + +E K Q E + +
Sbjct: 1516 LGSSGKTIHELEKVRKQLEAEKLELQSALEEAEASLEQEEGKILRAQLEFNQI 1568
>gi|21907902|dbj|BAC05681.1| myosin heavy chain slow [Equus caballus]
Length = 1935
Score = 1151 bits (2978), Expect = 0.0
Identities = 669/1895 (35%), Positives = 1065/1895 (55%), Gaps = 17/1895 (0%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K +VPD E F+ I ++ E + + VT+ D V + NPPKFDKIEDM+
Sbjct: 34 KKDVFVPDDKEEFVKAKIISREGGKITAE-TEHGKTVTVKEDQVLQQNPPKFDKIEDMAM 92
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LT+L+E +VL+NLKDRY + +IYTYSGLFCV INPYK LP+Y+ +++ ++GKKR E PP
Sbjct: 93 LTFLHEPAVLYNLKDRYAAWMIYTYSGLFCVTINPYKWLPVYTAEVVAAYRGKKRSEAPP 152
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIF+I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A A ++S
Sbjct: 153 HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIA-AIGDRS------ 205
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
K D + G LE Q+++ANP LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++
Sbjct: 206 -----KKDQTSGKGTLEDQIIEANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLAS 260
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYL-----LEGVDNYRFLVNR 960
A+IE YLLEKSRV+ Q + ER +HIFYQIL + +K E L +Y F+
Sbjct: 261 ADIETYLLEKSRVIFQLKAERDYHIFYQIL----SNKKPELLDMLLITNNPYDYAFISQG 316
Query: 961 GITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQ 1140
T+ ++DD +E +T N+ ++GF +E +S+ ++ A++ GN++F Q+++ +QA
Sbjct: 317 ETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKQKQREEQAEPD 376
Query: 1141 DDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLF 1320
K +L+GL +L K PR+KVG E+V K QN +Q +A A+AKA YER+F
Sbjct: 377 GTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVAYAKGALAKAVYERMF 436
Query: 1321 KWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFI 1500
W+V RIN +L+ T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF+
Sbjct: 437 NWMVARINATLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFV 495
Query: 1501 LEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKT 1680
LEQEEY++EGIEW+FIDFG+DLQ IDLIEKPMG++++L+EEC+FPKA D +F KL
Sbjct: 496 LEQEEYKKEGIEWEFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLFDN 555
Query: 1681 H-NKHPKFIVP---DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDP 1848
H K F P + ++HF+++HYAG VDY+ WL KN DPLNE VV L + S+
Sbjct: 556 HLGKSSNFQKPRNIKGKPEAHFSLIHYAGTVDYNILGWLQKNKDPLNETVVDLYKKSSLK 615
Query: 1849 FVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVR 2028
++ ++ A + G A E G + F+TVS LH+E L KLMT LR+T PHFVR
Sbjct: 616 MLSNLF--ANYLG--ADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVR 671
Query: 2029 CIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIP 2208
CIIPN K G I++ LV+ QLRCNGVLEGIRICR+GFPNR+ + +FR RY IL P IP
Sbjct: 672 CIIPNETKSPGVIDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIP 731
Query: 2209 K-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQ 2385
+ FID ++ K++++LDID N YR G +KVFF+ G+L LEE RD +L+ +I QAQ
Sbjct: 732 EGQFIDSRKGAEKLLSSLDIDHNQYRFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQ 791
Query: 2386 CRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRA 2565
RG L+R + N A++ ++NW W +L+ K+KPLL+ T+ E+
Sbjct: 792 SRGVLARMEFKKLLERRDSLLIIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMAT 851
Query: 2566 KDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTR 2745
+E KE L K E +E E+K+ ++ E+ +Q Q+Q E +N A+ ++ +L
Sbjct: 852 MKEEFARLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKN 911
Query: 2746 NQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNV 2925
+LE V +M +RL +RK + + +K
Sbjct: 912 KIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHAT 971
Query: 2926 DQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQL 3105
+ + L E++ KAK +LE +
Sbjct: 972 ENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQHV 1031
Query: 3106 HELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQL 3285
+LE L +E++ + +LE+ KRKL +L+ +++ + + ++L+ +L K+D EL
Sbjct: 1032 DDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALN 1091
Query: 3286 TRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVL 3465
R ++E A + +QK+++++Q I+EL E++E ER AR K E R ++ +LE++ + L
Sbjct: 1092 ARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEI-SERL 1150
Query: 3466 DKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQH 3642
++ AT +Q M++K E E KR +E+ E + K + V EL +QI+
Sbjct: 1151 EEAGGATSVQIEMNKKREAEFQKMKRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 1210
Query: 3643 KKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHK 3822
++ + +LEK++++ E D+ + + ++A+++K + E + E ++ E+
Sbjct: 1211 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSV 1270
Query: 3823 RTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANI 4002
L Q + + E L+R +E+E + + R T + K A
Sbjct: 1271 NDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALA 1330
Query: 4003 NRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN 4182
+ + + + L ++ EE +A L++ + A + R K E Q+ EEL +
Sbjct: 1331 HALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAK 1390
Query: 4183 LRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFE 4353
+ + LQ E E + + ++K ++Q E+ED +++E A+ +K+Q+ F+
Sbjct: 1391 KKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFD 1450
Query: 4354 SQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQ 4533
+AE + +++ + ++ +E R T + L N + EHLE R ++LQ+E+
Sbjct: 1451 KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEIS 1510
Query: 4534 DSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKS 4713
D GK +HELEK ++ LEAE +++ +EE E +L+ E LR ++ +K+
Sbjct: 1511 DLTEQLGSSGKTIHELEKVRKQLEAEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKA 1570
Query: 4714 ESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLE 4893
E +R ++ KD E E+ +R L+ + L+ L+ E R ++ A+ +KK+E + E+E QL
Sbjct: 1571 EIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLS 1630
Query: 4894 VANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLRE 5073
ANR+ E + QI+ ++A +A +D+ + +R+ ++AE E+LR
Sbjct: 1631 HANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA 1690
Query: 5074 ANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCEL 5244
E ++RK Q +K++++A ++Q C
Sbjct: 1691 VVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRD 1750
Query: 5245 AIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARA 5424
A +K +KA + +L E+ + E K+++E++ +D + ++ E E A +
Sbjct: 1751 AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKK 1810
Query: 5425 QMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEK 5604
Q+ LEA+V+ LE++L VE + + + R+ E+R+ + T Q E++++ + ++L++K
Sbjct: 1811 QLQKLEARVRELENELEVEQKRNAESIKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDK 1870
Query: 5605 SNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
LK + +RQ +EAE++ + +K R VQ E D+
Sbjct: 1871 LQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDE 1905
Score = 146 bits (369), Expect = 5e-33
Identities = 172/832 (20%), Positives = 349/832 (41%), Gaps = 24/832 (2%)
Frame = +1
Query: 3325 QKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVD-EATMLQDL 3501
+K+M M+ L+E +E R + E E + L + K D+ +V E L D
Sbjct: 846 EKEMATMKEEFARLKEALEKSEARRKELE----EKMVSLLQEKNDLQLQVQAEQDNLADA 901
Query: 3502 MSRKDEEVN-------ATKRAIEQIQ--HTMEGKIEEQKAKFSRQVEELHDQIEQHKKQR 3654
R D+ + K E+++ M ++ +K K + EL I+ +
Sbjct: 902 EERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTL 961
Query: 3655 SQLEKQQNQADQERADMAQEIALLQASRADIDKKRK-IHEAHLMEIQANLAESDEHKRTL 3831
+++EK+++ + + ++ +E+A L A + K++K + EAH + AE D+ TL
Sbjct: 962 AKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK-VNTL 1020
Query: 3832 IDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRA 4011
+ +D L E+E+ +++R A
Sbjct: 1021 TKAKVKLEQHVDDLEGSLEQEKKVRMDLER------------------------AKRKLE 1056
Query: 4012 RQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRD 4191
L+ + +++D + + + L L+K+ A AR + E+++ QL++ K+
Sbjct: 1057 GDLKLTQESIMDLENDKQQLDERLKKKDFELN--ALNARIEDEQALGSQLQKKLKELQAR 1114
Query: 4192 VEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEE 4371
+E L+++LE A+ ++ + + + +ELE+ S LE + + KK E++ +
Sbjct: 1115 IEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKM 1174
Query: 4372 RVAVQKALLDRDAMSQELRDRETRVLSLLNE-VDIMKEHLEESDRVRRSLQQELQDSISN 4548
+ +++A L +A + LR + ++ L E +D ++ ++ ++ + + EL D SN
Sbjct: 1175 KRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 1234
Query: 4549 KDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRA 4728
+ K LEK R+LE ++N+ R + EE + ++ R +L+ N E R
Sbjct: 1235 MEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTEN----GELSRQ 1290
Query: 4729 ISNKDVEAEEKRRGLL---KQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
+ K+ + RG L +Q+ DL+ +LE E + K+ + + L +Q E
Sbjct: 1291 LDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEE 1350
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIE--------CEEARQAKEDIAALLREADRKFRAVEAE 5055
K E +++ + EE +AK+ +A L++A+ AV A+
Sbjct: 1351 TEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAK 1410
Query: 5056 REQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKI-AQXXXXXXXXQS 5232
L + R Q R+ + ++K+R KI A+ QS
Sbjct: 1411 CSSLEKTKH-----RLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQS 1465
Query: 5233 NCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQS 5412
E +Q + ++T+L + +++ ++ +R N++ + +I++L S
Sbjct: 1466 ELE-------SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGS 1518
Query: 5413 RARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKE 5592
+ +++ + QL E E L+ L + E E+ +A+
Sbjct: 1519 SGKTIH-----ELEKVRKQLEAEKLE----------LQSALEEAEASLEHEEGKILRAQ- 1562
Query: 5593 LLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
LE + +K + R+L E ++EM + + H V LDA + E +
Sbjct: 1563 -LEFNQIK-AEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEAL 1612
Score = 136 bits (343), Expect = 5e-30
Identities = 173/836 (20%), Positives = 348/836 (40%), Gaps = 53/836 (6%)
Frame = +1
Query: 3364 LREDMETERNAR--NKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ----DLMSRKDEEV 3525
L E+M ER +R + + R V+A++E K +L++ D ++Q M K+
Sbjct: 772 LLEEMRDERLSRIITRIQAQSRGVLARMEFKK--LLERRDSLLIIQWNIRAFMGVKNWPW 829
Query: 3526 NATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADM 3705
I+ + + E E++ A + L + +E+ + +R +LE++ QE+ D+
Sbjct: 830 MKLYFKIKPLLKSAE--TEKEMATMKEEFARLKEALEKSEARRKELEEKMVSLLQEKNDL 887
Query: 3706 AQEIALLQASRADIDK------KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDEL 3864
++ Q + AD ++ K KI EA + E+ L + +E L + + DE
Sbjct: 888 QLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDEC 947
Query: 3865 DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALL 4044
L R ++ E A +++ K A N+ + L +E A L
Sbjct: 948 SELKRDIDDLELTLAKVEKE---------------------KHATENKVKNLTEEM-AGL 985
Query: 4045 DEKEEAEGLRAHLEKEIHAARQGAGEARR--KAEESVNQQLEELRKKNLRDVEHLQKQLE 4218
DE + A L KE A ++ +A +AEE L + + K + V+ L+ LE
Sbjct: 986 DE------IIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQHVDDLEGSLE 1039
Query: 4219 ESEVAKERILQSKKKIQQEL---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQK 4389
+ + + + ++K+K++ +L ++S M+LEN + D ++K FE R+ ++
Sbjct: 1040 QEKKVRMDLERAKRKLEGDLKLTQESIMDLENDK-QQLDERLKKKDFELNALNARIEDEQ 1098
Query: 4390 ALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFG-- 4563
AL + + ++L++ + R+ L E++ + + +++R L +EL++ ++ G
Sbjct: 1099 ALGSQ--LQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGA 1156
Query: 4564 ---------KNVHELEKAKRSLE----------AELN----DMRVQMEELEDNLQIAEDA 4674
K E +K KR LE A L D ++ E DNLQ +
Sbjct: 1157 TSVQIEMNKKREAEFQKMKRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQ- 1215
Query: 4675 RLRLEVTNQALKSESDRAISNKD------VEAEEKRRGLLKQIRDLENELENEKRGKSGA 4836
+LE K E D SN + E+ R L Q+ + ++ E +R +
Sbjct: 1216 --KLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDL 1273
Query: 4837 VSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALL 5016
S R K++ + GEL +QL+ L + + + + EE +AK +A L
Sbjct: 1274 TSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHAL 1333
Query: 5017 REA----DRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRL 5184
+ A D E E E E L +A + + E K++L
Sbjct: 1334 QSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 1393
Query: 5185 EAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSN 5364
++ + C + + Q ++E + D+ + ++++ ++
Sbjct: 1394 AQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKIL 1453
Query: 5365 RDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDT 5544
++K K E +S +S ++ + +L ++ L++ + R + L++ ++D
Sbjct: 1454 AEWKQKYEESQSELES-SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDL 1512
Query: 5545 TQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
T+Q + + +++ ++ + L+ L+EAE + E K Q E + +
Sbjct: 1513 TEQLGSSGKTIHELEKVRKQLEAEKLELQSALEEAEASLEHEEGKILRAQLEFNQI 1568
Score = 72.4 bits (176), Expect = 1e-10
Identities = 101/470 (21%), Positives = 193/470 (40%), Gaps = 36/470 (7%)
Frame = +1
Query: 4441 RVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELND 4620
++ LL + KE + R L++ L+ S + + ELE+ SL E ND
Sbjct: 835 KIKPLLKSAETEKEMATMKEEFAR-LKEALEKSEARRK-------ELEEKMVSLLQEKND 886
Query: 4621 MRVQMEELEDNLQIAE---DARLRLEVTNQA-LKSESDRAISNKDVEAE--EKRRGLLKQ 4782
+++Q++ +DNL AE D ++ ++ +A +K ++R +++ AE K+R L +
Sbjct: 887 LQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDE 946
Query: 4783 IRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL----EVANRLKEEYXXXXXXXXXX 4950
+L+ ++++ + + + EN++ L +++ E+ +L +E
Sbjct: 947 CSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKE--------KKA 998
Query: 4951 XXEYQIECEEARQAKEDIAALLREADRKFRA----VEAEREQLREANEGLMQARKQXXXX 5118
E + + QA+ED L +A K +E EQ ++ L +A+++
Sbjct: 999 LQEAHQQALDDLQAEEDKVNTLTKAKVKLEQHVDDLEGSLEQEKKVRMDLERAKRKLEGD 1058
Query: 5119 XXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRK---AQVQLEQI 5289
+ RL+ K + + L Q+K Q ++E++
Sbjct: 1059 LKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEEL 1118
Query: 5290 TTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQ 5469
+L ERT K E + L R + ++ E GA S EA+ Q ++
Sbjct: 1119 EEELEAERTARAKVEKLRSDLSRELEEISERLEE-AGGATSVQIEMNKKREAEFQKMKRD 1177
Query: 5470 LNVEGQEKTAANRA-ARRLEKRLNDTTQQFEDEKRANEQAKELLEK-------------S 5607
L +E T + A A L K+ D+ + ++ ++ K+ LEK S
Sbjct: 1178 L----EEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTS 1233
Query: 5608 NLK-----NRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
N++ NL + ED+M+ R+K QR +DL +L E
Sbjct: 1234 NMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTE 1283
>gi|8393807|ref|NP_058936.1| myosin heavy chain, polypeptide 7; myosin
heavy chain, cardiac muscle, fetal; myosin, heavy
polypeptide 7, cardiac muscle, beta; myosin heavy chain
polypeptide 7 cardiac muscle fetal; myosin heavy chain
cardiac muscle fetal; myosin heavy polypeptide 7 cardiac
muscle beta [Rattus norvegicus]
gi|127748|sp|P02564|MYH7_RAT Myosin heavy chain, cardiac muscle beta
isoform (MyHC-beta)
gi|92499|pir||S06006 myosin beta heavy chain, cardiac muscle
[similarity] - rat
gi|56657|emb|CAA34065.1| unnamed protein product [Rattus norvegicus]
Length = 1935
Score = 1147 bits (2967), Expect = 0.0
Identities = 666/1895 (35%), Positives = 1064/1895 (56%), Gaps = 17/1895 (0%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K +VPD E F+ I +V E + + VT+ D V + NPPKFDKIEDM+
Sbjct: 34 KKDVFVPDDKEEFVKAKIVSREGGKVTAE-TENGKTVTVKEDQVMQQNPPKFDKIEDMAM 92
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LT+L+E +VL+NLK+RY S +IYTYSGLFCV +NPYK LP+Y+ ++ ++GKKR E PP
Sbjct: 93 LTFLHEPAVLYNLKERYASWMIYTYSGLFCVTVNPYKWLPVYNAQVVAAYRGKKRSEAPP 152
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIF+I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A A ++S
Sbjct: 153 HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIA-AIGDRS------ 205
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
K D G LE Q++QANP LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++
Sbjct: 206 -----KKDQTPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLAS 260
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYL-----LEGVDNYRFLVNR 960
A+IE YLLEKSRV+ Q + ER +HIFYQIL + +K E L +Y F
Sbjct: 261 ADIETYLLEKSRVIFQLKAERDYHIFYQIL----SNKKPELLDMLLITNNPYDYAFFSQG 316
Query: 961 GITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQ 1140
T+ ++DD +E +T ++ ++GF +E +SI ++ A++ GN++F Q+++ +QA
Sbjct: 317 ETTVASIDDSEEHMATDSAFDVLGFTPEEKNSIYKLTGAIMHFGNMKFKQKQREEQAEPD 376
Query: 1141 DDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLF 1320
K +L+GL +L K PR+KVG E+V K QN +Q +A+ A+AK+ YE++F
Sbjct: 377 GTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVAYAIGALAKSVYEKMF 436
Query: 1321 KWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFI 1500
W+VTRIN +L+ T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF+
Sbjct: 437 NWMVTRINATLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFV 495
Query: 1501 LEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKT 1680
LEQEEY++EGIEW FIDFG+DLQ IDLIEKPMG++++L+EEC+FPKA D +F KL
Sbjct: 496 LEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLYDN 555
Query: 1681 H-NKHPKFIVP---DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDP 1848
H K F P + ++HF+++HYAG VDY+ WL KN DPLNE VVGL Q S+
Sbjct: 556 HLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLQKNKDPLNETVVGLYQKSSLK 615
Query: 1849 FVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVR 2028
++ ++ A +AG A + G + F+TVS LH+E L KLMT LR+T PHFVR
Sbjct: 616 LLSNLF--ANYAGADAPV--DKGKGKAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVR 671
Query: 2029 CIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIP 2208
CIIPN K G +++ LV+ QLRCNGVLEGIRICR+GFPNR+ + +FR RY IL P IP
Sbjct: 672 CIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIP 731
Query: 2209 K-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQ 2385
+ FID ++ K++ +LDID N Y+ G +KVFF+ G+L LEE RD +L+ +I QAQ
Sbjct: 732 EGQFIDSRKGAEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQ 791
Query: 2386 CRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRA 2565
RG LSR + N A++ ++NW W +L+ K+KPLL+ T+ E+
Sbjct: 792 SRGVLSRMEFKKLLERRDSLLIIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMAN 851
Query: 2566 KDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTR 2745
+E K+ L K E +E E+K+ ++ E+ +Q Q+Q E +N A+ ++ +L
Sbjct: 852 MKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKN 911
Query: 2746 NQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNV 2925
+LE V +M +RL +RK + + +K
Sbjct: 912 KIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHAT 971
Query: 2926 DQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQL 3105
+ + L E++ KAK +LE Q+
Sbjct: 972 ENKVKNLTEEMAGLDEIIVKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQV 1031
Query: 3106 HELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQL 3285
+LE L+++++ + +LE+ KRKL +L+ +++ + + ++L+ +L K+D EL
Sbjct: 1032 DDLEGSLDQDKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALN 1091
Query: 3286 TRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVL 3465
R ++E A + +QK+++++Q I+EL E++E ER AR K E R ++ +LE++ + L
Sbjct: 1092 ARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEI-SERL 1150
Query: 3466 DKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQH 3642
++ AT +Q M++K E E +R +E+ E + K + V EL +QI+
Sbjct: 1151 EEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 1210
Query: 3643 KKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHK 3822
++ + +LEK++++ E D+ + + ++A+++K + E + E ++ E+
Sbjct: 1211 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSV 1270
Query: 3823 RTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANI 4002
L Q + + E L+R +E+E + + R T + K A
Sbjct: 1271 NDLTRQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALA 1330
Query: 4003 NRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN 4182
+ + + + L ++ EE +A L++ + A + R K E Q+ EEL +
Sbjct: 1331 HALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAK 1390
Query: 4183 LRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFE 4353
+ + LQ E E + + ++K ++Q E+ED +++E A+ +K+Q+ F+
Sbjct: 1391 KKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFD 1450
Query: 4354 SQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQ 4533
+ E + +++ + ++ +E R T + L N + EHLE R ++LQ+E+
Sbjct: 1451 KILVEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEIS 1510
Query: 4534 DSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKS 4713
D GK++HELEK ++ LEAE +++ +EE E +L+ E LR ++ +K+
Sbjct: 1511 DLTEQLGSTGKSIHELEKIRKQLEAEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKA 1570
Query: 4714 ESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLE 4893
E +R ++ KD E E+ +R L+ + L+ L+ E R ++ A+ +KK+E + E+E QL
Sbjct: 1571 EIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLS 1630
Query: 4894 VANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLRE 5073
ANR+ E + QI+ ++A +A +D+ + +R+ ++AE E+LR
Sbjct: 1631 HANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA 1690
Query: 5074 ANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCEL 5244
E ++RK Q +K++++A ++Q C
Sbjct: 1691 VVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRN 1750
Query: 5245 AIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARA 5424
A +K +KA + +L E+ + E K ++E++ +D + ++ E E A +
Sbjct: 1751 AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKNNMEQTIKDLQHRLDEAEQIALKGGKK 1810
Query: 5425 QMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEK 5604
Q+ LEA+V+ LE++L E + + + R+ E+R+ + T Q E++++ + ++L++K
Sbjct: 1811 QLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDK 1870
Query: 5605 SNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
LK + +RQ +EAE++ + +K R VQ E D+
Sbjct: 1871 LQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDE 1905
Score = 145 bits (365), Expect = 2e-32
Identities = 163/824 (19%), Positives = 357/824 (42%), Gaps = 29/824 (3%)
Frame = +1
Query: 3364 LREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRA 3543
++E+ ++A K+E R+E+ EK+ + +K D +Q + +D +A +R
Sbjct: 852 MKEEFGRVKDALEKSEARRKELE---EKMVSLLQEKNDLQLQVQ---AEQDNLADAEERC 905
Query: 3544 IEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIAL 3723
+ I++ K + +V+E+ +++E ++ ++L ++ + + E +++ ++I
Sbjct: 906 DQLIKN---------KIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKRDIDD 956
Query: 3724 LQASRADIDKKRKIHEAHLMEIQANLAESDE-------HKRTL-------IDQLERSRDE 3861
L+ + A ++K++ E + + +A DE K+ L +D L+ D+
Sbjct: 957 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIVKLTKEKKALQEAHQQALDDLQAEEDK 1016
Query: 3862 LDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQ--LEDEKN 4035
++ L + + + E +++ L R+ + R + L+ +
Sbjct: 1017 VNTLTKAKVKLEQQVDDLEGSL------------DQDKKVRMDLERAKRKLEGDLKLTQE 1064
Query: 4036 ALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQL 4215
+++D + + + L L+K+ A AR + E+++ QL++ K+ +E L+++L
Sbjct: 1065 SIMDLENDKQQLDERLKKKDFELN--ALNARIEDEQALGSQLQKKLKELQARIEELEEEL 1122
Query: 4216 EESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKAL 4395
E A+ ++ + + + +ELE+ S LE + + KK E++ + R +++A
Sbjct: 1123 EAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEAT 1182
Query: 4396 LDRDAMSQELRDRETRVLSLLNE-VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNV 4572
L +A + LR + ++ L E +D ++ ++ ++ + + EL D SN + K
Sbjct: 1183 LQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAK 1242
Query: 4573 HELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEA 4752
LEK R+LE ++N+ R + EE + ++ R +L+ N E R + K+
Sbjct: 1243 ANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTRQRAKLQTEN----GELSRQLDEKEALI 1298
Query: 4753 EEKRRGLL---KQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYX 4923
+ RG L +Q+ DL+ +LE E + K+ + + L +Q E K E
Sbjct: 1299 SQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQ 1358
Query: 4924 XXXXXXXXXXXEYQIE--------CEEARQAKEDIAALLREADRKFRAVEAEREQLREAN 5079
+++ + EE +AK+ +A L++A+ AV A+ L +
Sbjct: 1359 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTK 1418
Query: 5080 EGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKI-AQXXXXXXXXQSNCELAIDK 5256
R Q R+ + ++K+R KI + QS E
Sbjct: 1419 H-----RLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILVEWKQKYEESQSELE----- 1468
Query: 5257 QRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAA 5436
+Q + ++T+L + +++ ++ +R N++ + +I++L S ++
Sbjct: 1469 --SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSTGKSIH-- 1524
Query: 5437 LEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLK 5616
+++ + QL E E L+ L + E E+ +A+ LE + +K
Sbjct: 1525 ---ELEKIRKQLEAEKLE----------LQSALEEAEASLEHEEGKILRAQ--LEFNQIK 1569
Query: 5617 NRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
+ R+L E ++EM + + H V LDA + E +
Sbjct: 1570 -AEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEAL 1612
Score = 131 bits (329), Expect = 2e-28
Identities = 159/831 (19%), Positives = 341/831 (40%), Gaps = 48/831 (5%)
Frame = +1
Query: 3364 LREDMETERNAR--NKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ----DLMSRKDEEV 3525
L E+M ER +R + + R V++++E K +L++ D ++Q M K+
Sbjct: 772 LLEEMRDERLSRIITRIQAQSRGVLSRMEFKK--LLERRDSLLIIQWNIRAFMGVKNWPW 829
Query: 3526 NATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADM 3705
I+ + + E E++ A + + D +E+ + +R +LE++ QE+ D+
Sbjct: 830 MKLYFKIKPLLKSAE--TEKEMANMKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDL 887
Query: 3706 AQEIALLQASRADIDK------KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDEL 3864
++ Q + AD ++ K KI EA + E+ L + +E L + + DE
Sbjct: 888 QLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDEC 947
Query: 3865 DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALL 4044
L R ++ E A +++ K A N+ + L +E L
Sbjct: 948 SELKRDIDDLELTLAKVEKE---------------------KHATENKVKNLTEEMAGL- 985
Query: 4045 DEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEES 4224
+E +K + A Q A + + E+ VN L + + K + V+ L+ L++
Sbjct: 986 ---DEIIVKLTKEKKALQEAHQQALDDLQAEEDKVNT-LTKAKVKLEQQVDDLEGSLDQD 1041
Query: 4225 EVAKERILQSKKKIQQEL---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKAL 4395
+ + + ++K+K++ +L ++S M+LEN + D ++K FE R+ ++AL
Sbjct: 1042 KKVRMDLERAKRKLEGDLKLTQESIMDLENDK-QQLDERLKKKDFELNALNARIEDEQAL 1100
Query: 4396 LDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVH 4575
+ + ++L++ + R+ L E++ + + +++R L +EL++ ++ G
Sbjct: 1101 GSQ--LQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATS 1158
Query: 4576 ELEKAKRSLEAELNDMRVQMEE----------------------LEDNLQIAEDARLRLE 4689
+ + EAE MR +EE L + + + + +LE
Sbjct: 1159 VQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 1218
Query: 4690 VTNQALKSESDRAISNKD------VEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRK 4851
K E D SN + E+ R L Q+ + ++ E +R + R
Sbjct: 1219 KEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTRQRA 1278
Query: 4852 KIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA-- 5025
K++ + GEL +QL+ L + + + + EE +AK +A L+ A
Sbjct: 1279 KLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARH 1338
Query: 5026 --DRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIA 5199
D E E E E L +A + + E K++L ++
Sbjct: 1339 DCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ 1398
Query: 5200 QXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKA 5379
+ C + + Q ++E + D+ + ++++ ++ ++K
Sbjct: 1399 DAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILVEWKQ 1458
Query: 5380 KITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFE 5559
K E +S +S ++ + +L ++ L++ + R + L++ ++D T+Q
Sbjct: 1459 KYEESQSELES-SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLG 1517
Query: 5560 DEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
++ + +++ ++ + L+ L+EAE + E K Q E + +
Sbjct: 1518 STGKSIHELEKIRKQLEAEKLELQSALEEAEASLEHEEGKILRAQLEFNQI 1568
Score = 71.6 bits (174), Expect = 2e-10
Identities = 86/429 (20%), Positives = 184/429 (42%), Gaps = 26/429 (6%)
Frame = +1
Query: 4525 ELQDSISN-KDDFGKNVHELEKAKR----------SLEAELNDMRVQMEELEDNLQIAED 4671
E + ++N K++FG+ LEK++ SL E ND+++Q++ +DNL AE+
Sbjct: 844 ETEKEMANMKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEE 903
Query: 4672 ARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRK 4851
D+ I NK ++ E K ++++ LE+E+ + + ++
Sbjct: 904 --------------RCDQLIKNK-IQLEAK-------VKEMTERLEDEEEMNAELTAKKR 941
Query: 4852 KIENQIGELEQ-----QLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALL 5016
K+E++ EL++ +L +A KE++ + + E++A L
Sbjct: 942 KLEDECSELKRDIDDLELTLAKVEKEKHATE---------------NKVKNLTEEMAGL- 985
Query: 5017 READRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKI 5196
D + E++ L+EA++ + + + K LE ++
Sbjct: 986 ---DEIIVKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVK-----------LEQQV 1031
Query: 5197 AQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKT----EAEKQSLER-- 5358
+ E ++D+ +K ++ LE+ L + L Q++ E +KQ L+
Sbjct: 1032 -----------DDLEGSLDQDKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERL 1080
Query: 5359 SNRDYKAKI----TELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLE 5526
+D++ E E S+ + ++ L+A+++ LE++L E + + L
Sbjct: 1081 KKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLS 1140
Query: 5527 KRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREAD 5706
+ L + +++ E+ A E+ +K + + +RR L+EA + E T ++ AD
Sbjct: 1141 RELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEA--TLQHEATAAALRKKHAD 1198
Query: 5707 DLLDANEQL 5733
+ + EQ+
Sbjct: 1199 SVAELGEQI 1207
Score = 57.4 bits (137), Expect = 4e-06
Identities = 69/330 (20%), Positives = 138/330 (40%), Gaps = 32/330 (9%)
Frame = +1
Query: 4852 KIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEAR--QAKEDIAALLREA 5025
KI+ + E + E+AN +KEE+ +E EAR + +E + +LL+E
Sbjct: 835 KIKPLLKSAETEKEMAN-MKEEFGRVKDA---------LEKSEARRKELEEKMVSLLQEK 884
Query: 5026 DRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEE---------KR 5178
+ V+AE++ L +A E Q K + + EE KR
Sbjct: 885 NDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMTER---LEDEEEMNAELTAKKR 941
Query: 5179 RLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLER 5358
+LE + ++ + ++ + +++ +T +++ + K EK++L+
Sbjct: 942 KLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIVKLTKEKKALQE 1001
Query: 5359 SNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLN 5538
+++ + E + +A++ LE +V LE L+ + + + RA R+LE L
Sbjct: 1002 AHQQALDDLQAEEDKVNTLTKAKVK-LEQQVDDLEGSLDQDKKVRMDLERAKRKLEGDLK 1060
Query: 5539 DTTQQFEDEKRANEQAKELLEKSNL---------------------KNRNLRRQLDEAED 5655
T + D + +Q E L+K + K + L+ +++E E+
Sbjct: 1061 LTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEE 1120
Query: 5656 EMSRERTKHRNVQREADDLLDANEQLTREL 5745
E+ ERT V++ DL E+++ L
Sbjct: 1121 ELEAERTARAKVEKLRSDLSRELEEISERL 1150
>gi|11276954|pir||A59234 slow myosin heavy chain 3 - quail
gi|1289512|gb|AAC59911.1| slow myosin heavy chain 3
gi|1289514|gb|AAC59912.1| slow myosin heavy chain 3
Length = 1931
Score = 1145 bits (2963), Expect = 0.0
Identities = 659/1892 (34%), Positives = 1059/1892 (55%), Gaps = 14/1892 (0%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
R LC+VP F+ I + V V +T +T+ DV NPPKFD+IEDM+
Sbjct: 27 RGLCFVPHPQLEFVRARITARAGNGVTVT-TETGETLTVPEADVHPQNPPKFDRIEDMAM 85
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LT+L+E +VL+NLK+RY S +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E+PP
Sbjct: 86 LTFLHEPAVLYNLKERYASWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRTEVPP 145
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIF+I+D AY++ML +RE+QSIL TGESGAGKT NTK+VIQY A +A K
Sbjct: 146 HIFSISDNAYQNMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRK------- 198
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
K + G LE Q++QANP LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++
Sbjct: 199 -----KEVANSSKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLAS 253
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLL--EGVDNYRFLVNRGIT 969
A+IE YLLEKSRV+ Q + ER++HIFYQIL E E LL +Y ++ +T
Sbjct: 254 ADIETYLLEKSRVIFQLKAERNYHIFYQILSN-KKPELLEMLLITNNPYDYSYVSQGEVT 312
Query: 970 LPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDR 1149
+ ++DD +E +T ++ ++GF +E + + ++ A++ GN++F Q+++ +QA
Sbjct: 313 VASIDDSEELLATDSAFDVLGFTAEEKAGVYKLTGAIMHFGNMKFKQKQREEQAEPDGTE 372
Query: 1150 VIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWL 1329
K +L+GL +L K PR+KVG E+V K Q+ +Q +++ A+AKA YE++F W+
Sbjct: 373 DADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWM 432
Query: 1330 VTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQ 1509
V RIN SL+ T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF+LEQ
Sbjct: 433 VVRINNSLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQ 491
Query: 1510 EEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-N 1686
EEY++EGIEW+FIDFG+DLQ IDLIEKPMG++++L+EEC+FPKA+D +F KL H
Sbjct: 492 EEYKKEGIEWEFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKASDMTFKAKLFDNHLG 551
Query: 1687 KHPKFIVP---DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVA 1857
K F P +S++HF+++HYAG VDY+ WL KN DPLNE VVGL Q S +A
Sbjct: 552 KSANFGKPRNVKGKSEAHFSLIHYAGTVDYNIIGWLEKNKDPLNETVVGLYQKSALKLLA 611
Query: 1858 GIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCII 2037
++ + +AG A + G + + F+TVS LH+E L KLM L+ T PHFVRC+I
Sbjct: 612 SLF--SNYAGADAGGDSGKGKGAKKKGSSFQTVSALHRENLNKLMANLKTTHPHFVRCLI 669
Query: 2038 PNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-N 2214
PN K+ G ++++LV+ QLRCNGVLEGIRICR+GFPNR+ + +FR RY IL P IP+
Sbjct: 670 PNERKEPGVMDNSLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPTAIPEGQ 729
Query: 2215 FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRG 2394
FID ++ K++ +LDID N Y+ G +KVFF+ G+L LEE RD +L+ +I QAQ RG
Sbjct: 730 FIDSRKGAEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSLIITRIQAQARG 789
Query: 2395 FLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDD 2574
L R + N A++ ++NW W +L+ K+KPLL+ T+ E++ +
Sbjct: 790 QLMRIEFKKILERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMQTMKE 849
Query: 2575 ELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQE 2754
E KE L K E +E E+K+ ++ E+ +Q Q+Q E +N A+ ++ +L +
Sbjct: 850 EFGHLKEALEKSEARRKELEEKMVSMLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQ 909
Query: 2755 LEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQX 2934
LE V +M +RL +RK + + +K +
Sbjct: 910 LEAKVKEMTERLEEEEEMNAELTAKKRKLEDECSELKKDIDDLELSLAKVEKEKHATENK 969
Query: 2935 XXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHEL 3114
+ L E++ KAK +LE Q +L
Sbjct: 970 VKNLTEEMAGLDENITKLTKEKKTLQESHQQALDDLQAEEDKVNTLAKAKVKLEQQADDL 1029
Query: 3115 EQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRY 3294
E L +E++ + +LE+ KRKL +L+ +++ + + ++L +L K+D EL R
Sbjct: 1030 ESSLQQEKKIRMDLERAKRKLEGDLKLAQESVMDLENDKQQLEERLKKKDFELNTLNARI 1089
Query: 3295 DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKV 3474
++E A +QK+++++Q I+EL E++E ER R K E R E++ +LE+ + L++
Sbjct: 1090 EDEQAIAAQLQKKLKELQARIEELEEELEAERTGRAKVEKLRSELLQELEET-SERLEEA 1148
Query: 3475 DEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQ 3651
AT +Q +L +++ E +R +E+ E + K + V EL +Q++ ++
Sbjct: 1149 GGATSVQLELNKKREAEFQKLRRDLEEATLQHEATAAALRKKHADSVAELSEQLDNMQRV 1208
Query: 3652 RSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTL 3831
+ +LEK++++ E D++ + L ++A+++K + E + E + L ES L
Sbjct: 1209 KQKLEKEKSELKLELDDVSSNMEQLIKAKANLEKMCRSTEDQMNEHRNKLEESQRTVTDL 1268
Query: 3832 IDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRA 4011
Q + + E L+R EE+E + R T + K A +
Sbjct: 1269 STQRAKLQTENSELSRQLEEKEAFINQLMRGKLTYTQQLEDLKRQLEEEAKAKNALAHAL 1328
Query: 4012 RQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRD 4191
+ + + + L ++ EE +A L++ + A + R K E Q+ EEL + +
Sbjct: 1329 QSAQHDCDLLREQYEEEMEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 1388
Query: 4192 VEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQM 4362
+ LQ+ E E + + ++K ++Q E+ED ++E A+ +K+Q+ F+ +
Sbjct: 1389 AQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMADVERSNAAAAALDKKQRNFDKIL 1448
Query: 4363 AEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSI 4542
+E + +++ + +A +E R T + L N + EHLE R ++LQ+E+ D
Sbjct: 1449 SEWKQKFEESQTELEASQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLT 1508
Query: 4543 SNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESD 4722
K++HELEK ++ L+AE +++ +EE E +L+ E LR ++ +K+E +
Sbjct: 1509 EQLGASQKSIHELEKVRKQLDAEKLELQAALEEAEASLEHEEGKILRAQLEFNQVKAEYE 1568
Query: 4723 RAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVAN 4902
R ++ KD E E+ +R L+ + L+ L+ E R ++ A+ +KK+E + E+E QL AN
Sbjct: 1569 RKLAEKDEEMEQSKRNHLRVVDSLQTSLDAETRSRNEALRLKKKMEGDLNEMEIQLSHAN 1628
Query: 4903 RLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANE 5082
R E + Q++ ++A +A ED+ + +R+ +++E E+LR E
Sbjct: 1629 RTAAEAQKQVKALQGYLKDTQLQLDDAVRANEDLKENIAIVERRNNLLQSELEELRAMVE 1688
Query: 5083 GLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAID 5253
+ARK Q +K+++EA I+Q C A +
Sbjct: 1689 QSERARKLAEQELTEASERVQLLHSQNTSLINQKKKMEADISQLQTEVEEAIQECRNAEE 1748
Query: 5254 KQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMA 5433
K +KA + +L E+ + E K+++E++ +D + ++ E E A + Q+
Sbjct: 1749 KAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQLQ 1808
Query: 5434 ALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNL 5613
LEA+V+ LE++L E + + + R+ E+R+ + + Q E++++ + ++L++K L
Sbjct: 1809 KLEARVRELENELEAEQKHNAESIKGLRKSERRVKELSYQTEEDRKNMVRLQDLVDKLQL 1868
Query: 5614 KNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
K + +RQ +EAE++ + K R Q E D+
Sbjct: 1869 KVKAYKRQAEEAEEQANSNLAKFRKAQHELDE 1900
Score = 156 bits (395), Expect = 5e-36
Identities = 176/831 (21%), Positives = 364/831 (43%), Gaps = 23/831 (2%)
Frame = +1
Query: 3325 QKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLM 3504
+K+M+ M+ L+E +E K+E R+E+ EK+ + +K D +Q
Sbjct: 841 EKEMQTMKEEFGHLKEALE-------KSEARRKELE---EKMVSMLQEKNDLQLQVQ--- 887
Query: 3505 SRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQA 3684
+ +D +A +R + I++ K + +V+E+ +++E+ ++ ++L ++ +
Sbjct: 888 AEQDNLADAEERCDQLIKN---------KIQLEAKVKEMTERLEEEEEMNAELTAKKRKL 938
Query: 3685 DQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEH-------KRTLIDQL 3843
+ E +++ ++I L+ S A ++K++ E + + +A DE+ K+TL +
Sbjct: 939 EDECSELKKDIDDLELSLAKVEKEKHATENKVKNLTEEMAGLDENITKLTKEKKTLQESH 998
Query: 3844 ERSRDELDHLNRVREEEEHAFANMQRRLAT-AXXXXXXXXXXXXXXTRLKIANINRARQL 4020
+++ D+L + E++ + A + +L A L+ A L
Sbjct: 999 QQALDDL----QAEEDKVNTLAKAKVKLEQQADDLESSLQQEKKIRMDLERAKRKLEGDL 1054
Query: 4021 EDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEH 4200
+ + +++D + + + L L+K+ AR + E+++ QL++ K+ +E
Sbjct: 1055 KLAQESVMDLENDKQQLEERLKKKDFELN--TLNARIEDEQAIAAQLQKKLKELQARIEE 1112
Query: 4201 LQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVA 4380
L+++LE + ++ + + ++ QELE++S LE + + KK E++ + R
Sbjct: 1113 LEEELEAERTGRAKVEKLRSELLQELEETSERLEEAGGATSVQLELNKKREAEFQKLRRD 1172
Query: 4381 VQKALLDRDAMSQELRDRET-RVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDD 4557
+++A L +A + LR + V L ++D M+ ++ ++ + L+ EL D SN +
Sbjct: 1173 LEEATLQHEATAAALRKKHADSVAELSEQLDNMQRVKQKLEKEKSELKLELDDVSSNMEQ 1232
Query: 4558 FGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISN 4737
K LEK RS E ++N+ R ++EE + + R +L+ N SE R +
Sbjct: 1233 LIKAKANLEKMCRSTEDQMNEHRNKLEESQRTVTDLSTQRAKLQTEN----SELSRQLEE 1288
Query: 4738 KDVEAEEKRRGLL---KQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRL 4908
K+ + RG L +Q+ DL+ +LE E + K+ + ++ L +Q E
Sbjct: 1289 KEAFINQLMRGKLTYTQQLEDLKRQLEEEAKAKNALAHALQSAQHDCDLLREQYEEEMEA 1348
Query: 4909 KEEYXXXXXXXXXXXXEYQIE--------CEEARQAKEDIAALLREADRKFRAVEAEREQ 5064
K E +++ + EE +AK+ +A L+EA+ AV A+
Sbjct: 1349 KAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSS 1408
Query: 5065 LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCEL 5244
L + R Q R+ + ++K+R KI +S EL
Sbjct: 1409 LEKTKH-----RLQNEIEDLMADVERSNAAAAALDKKQRNFDKILSEWKQKFE-ESQTEL 1462
Query: 5245 AIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARA 5424
+Q + ++T+L + +++ ++ +R N++ + +I++L
Sbjct: 1463 -----EASQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTE-------- 1509
Query: 5425 QMAALEAKVQYLED---QLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKEL 5595
Q+ A + + LE QL+ E E AA A + + + E+ K Q
Sbjct: 1510 QLGASQKSIHELEKVRKQLDAEKLELQAALEEA--------EASLEHEEGKILRAQ---- 1557
Query: 5596 LEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
LE + +K R+L E ++EM + + H V LDA + E +
Sbjct: 1558 LEFNQVK-AEYERKLAEKDEEMEQSKRNHLRVVDSLQTSLDAETRSRNEAL 1607
>gi|31235848|ref|XP_319310.1| ENSANGP00000024621 [Anopheles gambiae]
gi|30174789|gb|EAA43615.1| ENSANGP00000024621 [Anopheles gambiae str.
PEST]
Length = 1937
Score = 1145 bits (2962), Expect = 0.0
Identities = 677/1913 (35%), Positives = 1085/1913 (56%), Gaps = 28/1913 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K CWVP++ EG+++G IK T E++ + + ++ + + NPPKF+K+EDM++
Sbjct: 36 KKACWVPEEKEGYVLGEIKA-TKGELVTVALPGGEEKNFKKEQLSQVNPPKFEKVEDMAD 94
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LTYLNEA+VLHNL+ RYYS LIYTYSGLFCVVINPYK+ P+Y+ + ++GK+R+E+PP
Sbjct: 95 LTYLNEAAVLHNLRQRYYSKLIYTYSGLFCVVINPYKRYPLYTNRCAKMYRGKRRNEVPP 154
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
H+FA++D AY +ML E+QS+L TGESGAGKTENTKKVI Y A + GA+ K NA +
Sbjct: 155 HLFAVSDGAYVNMLTNHENQSMLITGESGAGKTENTKKVIAYFATI-GASGKKDENAEKK 213
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
G LE Q++Q NP+LEAFGN+KTV+NDNSSRFGKFIRI+F SG ++G
Sbjct: 214 -------------GSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFTGSGKLAG 260
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLL-EGVDNYRFLVNRGITL 972
A+IE YLLEK+RV+ Q ERS+HIFYQI+ G K + LL + +Y + T+
Sbjct: 261 ADIETYLLEKARVISQQTLERSYHIFYQIMSGSVKGLKEKCLLSNNIHDYHIVAQGKTTI 320
Query: 973 PNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRV 1152
P+VDD +E T + ++GF +E +I R+ SAV+ +G ++F Q+ + +QA
Sbjct: 321 PSVDDGEEMQITDEAFNVLGFTQEEKDNIYRITSAVMHMGRMQFKQKGREEQAEADGTED 380
Query: 1153 IQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLV 1332
+V LLG+ +L K L+PRIKVG EFV K QN++Q +V A+ K ++RLFKWLV
Sbjct: 381 GDRVAKLLGVGTDDLYKNLLKPRIKVGNEFVTKGQNKDQVTNSVGALCKGIFDRLFKWLV 440
Query: 1333 TRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQE 1512
+ N++LD T ++ A FIG+LDIAGFEIFD N FEQ+CIN+TNEKLQQ FN+ MF+LEQE
Sbjct: 441 KKCNETLD-TKQKRAQFIGVLDIAGFEIFDFNGFEQLCINFTNEKLQQFFNHHMFVLEQE 499
Query: 1513 EYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NK 1689
EYQREGIEW FIDFG+DLQ I+LIEKPMG+L++L+EE +FPKA D++F EKL H K
Sbjct: 500 EYQREGIEWTFIDFGMDLQQCIELIEKPMGILSILEEESMFPKATDQTFAEKLMTNHLGK 559
Query: 1690 HPKFIVPDMRS----KSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVA 1857
F+ P HFA+ HYAG V Y+ WL KN DPLN+ VV + ++ +
Sbjct: 560 SAPFMKPRPPKPGIPAGHFAIGHYAGVVSYNITGWLEKNKDPLNDTVVDQFKKGSNALMV 619
Query: 1858 GIWKD--AEFAGICAAEMNETAFGMRSRKGM-FRTVSQLHKEQLTKLMTTLRNTSPHFVR 2028
I+ D + A AA+ G R +KG F TVS +KEQL LMTTL++T PHFVR
Sbjct: 620 EIFADHPGQSADPAAAK------GGRGKKGAGFATVSSSYKEQLNNLMTTLKSTQPHFVR 673
Query: 2029 CIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIP 2208
CIIPN K +G ++++LV+ QL CNGVLEGIRICR+GFPNR+ + +F+ RY+IL P +I
Sbjct: 674 CIIPNEMKTAGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKLRYKILCPQLI- 732
Query: 2209 KNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQC 2388
K ++ + ++T + + +R+G++KVFFR GVL +EE RD +L+ ++ QA C
Sbjct: 733 KEPCSPEKVTQIVLTHIQLPEEQFRMGKTKVFFRAGVLGQMEEFRDERLSKIMSWMQAWC 792
Query: 2389 RGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAK 2568
RG+LSR+ + N YLKLR W WW+L+ KVKPLL V+R +D+I
Sbjct: 793 RGYLSRKEFKKMQEQRVSLEIVQRNLRKYLKLRTWAWWKLWQKVKPLLNVSRVEDQIAKL 852
Query: 2569 DDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRN 2748
+++ +E K E +E E +++ E+ + + L E E + +L +
Sbjct: 853 EEKATKAQEAYEKEEKLRKELEALNSKLLAEKTALLDSLSGEKGALQEYQEKAAKLTAQK 912
Query: 2749 QELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVD 2928
+LE + D ++RL+ ++K + + DK + D
Sbjct: 913 NDLENQLRDTQERLAQEEDARNQLFQTKKKLEQEIGSQKKDAEDLELQIQKIEQDKASKD 972
Query: 2929 QXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLH 3108
+ + +L E++ H K K +LE L
Sbjct: 973 HQIRNLNDEIAHQDELINKLNKEKKMQGEVNQKTAEELQAAEDKVNHLNKVKAKLEQTLD 1032
Query: 3109 ELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLT 3288
ELE L RE++ + ++E+ KRK+ +L+ +++ +A+ +EL ++++D+E+
Sbjct: 1033 ELEDSLEREKKLRGDVEKAKRKVEGDLKLTQEAVADLERNKKELEQTVLRKDKEISALSA 1092
Query: 3289 RYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLD 3468
+ ++E + V +QKQ++++Q I+EL E++E ER AR KAE R ++ +LE++ G+ L+
Sbjct: 1093 KLEDEQSLVGKLQKQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEEL-GERLE 1151
Query: 3469 KVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHK 3645
+ AT Q +L +++ E+ +R +E+ EG + + K + V E+ +Q++Q
Sbjct: 1152 EAGGATSAQIELNKKREAELAKLRRDLEEANIQHEGTLANLRKKHNDAVAEMAEQVDQLN 1211
Query: 3646 KQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKR 3825
K +++ EK++ Q E D L +A +K K + L E+Q+ L DE R
Sbjct: 1212 KLKTKAEKERTQYFAELNDARIGCDQLSNEKAAQEKIAKQLQHTLNEVQSKL---DETNR 1268
Query: 3826 TLIDQLERSRDEL----DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKI 3993
TL D + S+ +L L R E+ E + + + + R +
Sbjct: 1269 TLND-FDASKKKLSIENSDLLRQLEDAESQVSQLSKIKISLTQQLEDTKRLADEEARERA 1327
Query: 3994 ANINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHAARQGAGEARRKAEE---SVNQQL 4161
+ + R LE + + L ++ +EEAEG + +++++ A A R K E + ++L
Sbjct: 1328 TLLGKFRNLEHDLDNLREQVEEEAEG-KGDIQRQLSKANAEAQLWRSKYESEGVARAEEL 1386
Query: 4162 EELRKK---NLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSE 4332
EE ++K L + E + L + +A E+ +K+++ E+ED +E++ + +E
Sbjct: 1387 EEAKRKLQARLAEAEETIESLNQKCIALEK---TKQRLATEVEDLQLEVDRASSIANAAE 1443
Query: 4333 KRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRR 4512
K+QK F+ + E ++ V + DA +E R+ T + L + +E LE R +
Sbjct: 1444 KKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENK 1503
Query: 4513 SLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEV 4692
+L E++D + + G+N+HE+EK+++ LEAE ++++ +EE E L+ E+ LR ++
Sbjct: 1504 NLADEVKDLLDQIGEGGRNIHEIEKSRKRLEAEKDELQAALEEAEAALEQEENKVLRAQL 1563
Query: 4693 TNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIG 4872
++ E DR I K+ E E R+ + + ++ LE E +GK+ A+ +KK+E I
Sbjct: 1564 ELSQVRQEIDRRIQEKEEEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADIN 1623
Query: 4873 ELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEA 5052
ELE L+ AN+ E + Q EE ++A++D L ++R+ A++
Sbjct: 1624 ELEIALDHANKANAEAQKNIKRYQQQLKDVQSALEEEQRARDDAREQLGISERRANALQN 1683
Query: 5053 EREQ----LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXX 5220
E E+ L +A+ G QA ++ A+ I++ KR+LE+++
Sbjct: 1684 ELEESRTLLEQADRGRRQAEQELSDAHEQLNEVSAQNASIAA-AKRKLESELQTLHSDLD 1742
Query: 5221 XXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES 5400
+ + + +K +KA V ++ +L E+ Q E +++LE+ ++ + ++ E ES
Sbjct: 1743 ELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAES 1802
Query: 5401 GAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANE 5580
A + + LE +V+ LE +L+ E + A + R+ E+R+ + T Q E++++ +E
Sbjct: 1803 NALKGGKKAIQKLEQRVRELESELDSEQRRHADAQKNLRKSERRIKELTFQSEEDRKNHE 1862
Query: 5581 QAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQR---EADDLLDANEQ 5730
+ ++L++K K + +RQ++EAE+ + K R Q+ EA++ D EQ
Sbjct: 1863 RMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADIAEQ 1915
Score = 155 bits (391), Expect = 1e-35
Identities = 186/948 (19%), Positives = 398/948 (41%), Gaps = 60/948 (6%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMK--- 3258
+LE + + ++ +E + + ELE KLLAE D L+ + G ++E + K
Sbjct: 851 KLEEKATKAQEAYEKEEKLRKELEALNSKLLAEKTALLDSLSGEKGALQEYQEKAAKLTA 910
Query: 3259 RDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQ 3438
+ +L++QL E A Q D + + + ++ +E E ++ K ++ Q
Sbjct: 911 QKNDLENQLRDTQERLA-------QEEDARNQLFQTKKKLEQEIGSQKK---DAEDLELQ 960
Query: 3439 LEKVKGDVLDKVDEATMLQDLMSRKDEEVN-----------ATKRAIEQIQHTME--GKI 3579
++K++ D K + L D ++ +DE +N ++ E++Q + +
Sbjct: 961 IQKIEQDKASKDHQIRNLNDEIAHQDELINKLNKEKKMQGEVNQKTAEELQAAEDKVNHL 1020
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKR 3759
+ KAK + ++EL D +E+ KK R +EK + + + + + L Q + AD+++ +
Sbjct: 1021 NKVKAKLEQTLDELEDSLEREKKLRGDVEKAKRKVEGD-------LKLTQEAVADLERNK 1073
Query: 3760 KIHEAHLM----EIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRL 3927
K E ++ EI A L+ E +++L+ +L++ EL R+ E EE A Q R
Sbjct: 1074 KELEQTVLRKDKEISA-LSAKLEDEQSLVGKLQKQIKELQA--RIEELEEEVEAERQAR- 1129
Query: 3928 ATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAAR 4107
+ + + AR+LE+ L E+ E G + E++ R
Sbjct: 1130 -----------------AKAEKQRADLARELEE-----LGERLEEAGGATSAQIELNKKR 1167
Query: 4108 QGAGEARRKAEESVNQQ----LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQE 4275
+ R+ E N Q L LRKK+ V + +Q+++ K + + + + E
Sbjct: 1168 EAELAKLRRDLEEANIQHEGTLANLRKKHNDAVAEMAEQVDQLNKLKTKAEKERTQYFAE 1227
Query: 4276 LEDSSM---ELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRV 4446
L D+ + +L N +A+ K+ + +++ + + L D DA ++L +
Sbjct: 1228 LNDARIGCDQLSNEKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSIENS-- 1285
Query: 4447 LSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMR 4626
LL +++ + + + +++ SL Q+L+D+ D+ + L R+LE +L+++R
Sbjct: 1286 -DLLRQLEDAESQVSQLSKIKISLTQQLEDTKRLADEEARERATLLGKFRNLEHDLDNLR 1344
Query: 4627 VQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENEL 4806
Q+EE + + + Q +S+ + + E EE +R L ++ + E +
Sbjct: 1345 EQVEEEAEGKGDIQRQLSKANAEAQLWRSKYESEGVARAEELEEAKRKLQARLAEAEETI 1404
Query: 4807 ENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEAR 4986
E+ + ++++ ++ +L+ +++ A+ + E++++ ++
Sbjct: 1405 ESLNQKCIALEKTKQRLATEVEDLQLEVDRASSIANAAEKKQKAFDKIIGEWKLKVDDLA 1464
Query: 4987 QAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISS 5166
+ R + ++ E+ +E E + + K +GG
Sbjct: 1465 AELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGRNIH 1524
Query: 5167 E---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEA 5337
E ++RLEA+ + ++ E +K +AQ++L Q+ ++ +R + +K E
Sbjct: 1525 EIEKSRKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEI--DRRIQEKEEE 1582
Query: 5338 EKQSLERSNRDYKAKITELESGAQSRARA--QMAALEAKVQYLEDQLNVEGQEKTAANRA 5511
+ + + R + LE+ A+ +A A LEA + LE L+ + A +
Sbjct: 1583 FENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQKN 1642
Query: 5512 ARRLEKRLNDTTQQFEDEKR----------------------------ANEQAKELLEKS 5607
+R +++L D E+E+R EQA ++
Sbjct: 1643 IKRYQQQLKDVQSALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRRQA 1702
Query: 5608 NLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
+ + QL+E + + R ++ E L ++L E N
Sbjct: 1703 EQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDELLNEAKN 1750
Score = 109 bits (272), Expect = 9e-22
Identities = 138/637 (21%), Positives = 266/637 (41%), Gaps = 88/637 (13%)
Frame = +1
Query: 3028 LTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDH 3207
L QL D E + K K L QL + ++ + E + ++ L R L +L++ ++
Sbjct: 1287 LLRQLEDAESQVSQLSKIKISLTQQLEDTKRLADEEARERATLLGKFRNLEHDLDNLREQ 1346
Query: 3208 LAEKMGKVEELNNQLMKRDEELQHQLTRYDEES-ANVTLMQKQMRDMQTTIDELREDMET 3384
+ E+ ++ QL K + E Q ++Y+ E A +++ R +Q + E E +E+
Sbjct: 1347 VEEEAEGKGDIQRQLSKANAEAQLWRSKYESEGVARAEELEEAKRKLQARLAEAEETIES 1406
Query: 3385 ERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRK----DEEVNATKRAIEQ 3552
E T++ + ++E D+ +VD A+ + + +K D+ + K ++
Sbjct: 1407 LNQKCIALEKTKQRLATEVE----DLQLEVDRASSIANAAEKKQKAFDKIIGEWKLKVDD 1462
Query: 3553 IQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQA 3732
+ ++ +E + +S ++ L E+ ++Q + ++ E D+ +I
Sbjct: 1463 LAAELDASQKECR-NYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGR 1521
Query: 3733 SRADIDKKRKIHEAHLMEIQANLAESD-----EHKRTLIDQLERS--RDELDHLNRVREE 3891
+ +I+K RK EA E+QA L E++ E + L QLE S R E+D + +EE
Sbjct: 1522 NIHEIEKSRKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEIDRRIQEKEE 1581
Query: 3892 E-EHAFANMQRRLATAXXXXXXXXXXXXXXTRLKI---ANINRARQLEDEKNALLDE--- 4050
E E+ N QR L + R+K A+IN D N E
Sbjct: 1582 EFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQK 1641
Query: 4051 -----KEEAEGLRAHLEKEIHA---ARQGAGEARRKAEESVNQ---------QLEELRKK 4179
+++ + +++ LE+E A AR+ G + R+A N+ Q + R++
Sbjct: 1642 NIKRYQQQLKDVQSALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRRQ 1701
Query: 4180 NLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKF--- 4350
+++ +QL E I +K+K++ EL+ +L+ + ++SE++ KK
Sbjct: 1702 AEQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDELLNEAKNSEEKAKKAMVD 1761
Query: 4351 ------ESQMAEERVAVQKALLDRDAMSQELRDR----------------------ETRV 4446
E + ++ Q+ L R A+ Q++++ E RV
Sbjct: 1762 AARLADELRAEQDHAQTQEKL--RKALEQQIKELQVRLDEAESNALKGGKKAIQKLEQRV 1819
Query: 4447 LSLLNEVDI-MKEHLE-------------------ESDRVRRSLQQELQDSISNK-DDFG 4563
L +E+D + H + E DR Q+L D + K +
Sbjct: 1820 RELESELDSEQRRHADAQKNLRKSERRIKELTFQSEEDRKNHERMQDLVDKLQQKIKTYK 1879
Query: 4564 KNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDA 4674
+ + E E+ A+ + ++EE E+ IAE A
Sbjct: 1880 RQIEEAEEIAALNLAKFRKAQQELEEAEERADIAEQA 1916
Score = 89.7 bits (221), Expect = 8e-16
Identities = 111/532 (20%), Positives = 233/532 (42%), Gaps = 11/532 (2%)
Frame = +1
Query: 4180 NLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQ 4359
N+ VE +LEE + + ++K+++ELE + +L + + DS +K
Sbjct: 841 NVSRVEDQIAKLEEKATKAQEAYEKEEKLRKELEALNSKLLAEKTALLDSLSGEK---GA 897
Query: 4360 MAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDS 4539
+ E + K ++ + +LRD + R L E D + + ++ L+QE+
Sbjct: 898 LQEYQEKAAKLTAQKNDLENQLRDTQER---LAQEEDARNQLFQ----TKKKLEQEIGSQ 950
Query: 4540 ISNKDDFGKNVHELEKAKRSLEAE---LNDMRVQMEELEDNLQIAEDARLRLEVTNQALK 4710
+ +D + ++E+ K S + + LND +EL + L ++ +++ EV +
Sbjct: 951 KKDAEDLELQIQKIEQDKASKDHQIRNLNDEIAHQDELINKLN--KEKKMQGEVNQKT-- 1006
Query: 4711 SESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
+E +A +K + + L + + +LE+ LE EK+ + ++K+E + ++ +
Sbjct: 1007 AEELQAAEDKVNHLNKVKAKLEQTLDELEDSLEREKKLRGDVEKAKRKVEGDLKLTQEAV 1066
Query: 4891 EVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLR 5070
R K+E + +I A+ ED +L+ + ++ + ++A E+L
Sbjct: 1067 ADLERNKKELEQTVLRK-----DKEISALSAKL--EDEQSLVGKLQKQIKELQARIEELE 1119
Query: 5071 EANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAI 5250
E E QAR AK ++ R LE + + EL
Sbjct: 1120 EEVEAERQAR--------------AKAEKQRADLARELEELGERLEEAGGATSAQIEL-- 1163
Query: 5251 DKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITE-------LESGAQ 5409
+K + +L ++ DL ++ T A +L + + D A++ E L++ A+
Sbjct: 1164 --NKKREAELAKLRRDLEEANIQHEGTLA---NLRKKHNDAVAEMAEQVDQLNKLKTKAE 1218
Query: 5410 SRARAQMAAL-EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQA 5586
A L +A++ DQL+ EK A + A++L+ LN+ + ++ R
Sbjct: 1219 KERTQYFAELNDARIGC--DQLS---NEKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDF 1273
Query: 5587 KELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
+K +++N +L RQL++AE ++S+ ++ ++ +D ++ RE
Sbjct: 1274 DASKKKLSIENSDLLRQLEDAESQVSQLSKIKISLTQQLEDTKRLADEEARE 1325
Score = 79.7 bits (195), Expect = 8e-13
Identities = 81/418 (19%), Positives = 183/418 (43%), Gaps = 25/418 (5%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L +Q+ E ++++ + + LE K +L A LE+++ L ++ KV +L + +E
Sbjct: 1512 LLDQIGEGGRNIHEIEKSRKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQE 1571
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ ++ +EE N ++ Q +D ++ +E E + +A ++++ A + ++
Sbjct: 1572 IDRRIQEKEEEFENTR------KNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINEL 1625
Query: 3451 KGDVLDKVDEATM-LQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+ LD ++A Q + R +++ + A+E+ Q + EQ R+ L +
Sbjct: 1626 E-IALDHANKANAEAQKNIKRYQQQLKDVQSALEEEQRARDDA-REQLGISERRANALQN 1683
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL-- 3801
++E+ + Q ++ + QA+QE +D +++ + A A I ++ E+ L + ++L
Sbjct: 1684 ELEESRTLLEQADRGRRQAEQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDE 1743
Query: 3802 ----AESDEHKRT--------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
A++ E K L D+L +D ++R+ E +Q RL A
Sbjct: 1744 LLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAESN 1803
Query: 3946 XXXXXXXXXXXTRLKIANIN------RARQLEDEKNALLDEKEEAE-GLRAHLEKEIHAA 4104
++ + + R + +KN E+ E ++ +++ H
Sbjct: 1804 ALKGGKKAIQKLEQRVRELESELDSEQRRHADAQKNLRKSERRIKELTFQSEEDRKNHER 1863
Query: 4105 RQGAGEARRKAEESVNQQLEELRK---KNLRDVEHLQKQLEESEVAKERILQSKKKIQ 4269
Q + ++ ++ +Q+EE + NL Q++LEE+E + Q+ K +
Sbjct: 1864 MQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADIAEQAATKFR 1921
Score = 53.9 bits (128), Expect = 5e-05
Identities = 62/408 (15%), Positives = 157/408 (38%), Gaps = 12/408 (2%)
Frame = +1
Query: 2533 QVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAE 2712
++ ++ + A+ DEL+A E + E + E K+ + +E + +++++ + + E
Sbjct: 1525 EIEKSRKRLEAEKDELQAALE---EAEAALEQEENKVLRAQLELSQVRQEIDRRIQEKEE 1581
Query: 2713 LDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXX 2892
+ + + ++ M+ L ++K + +
Sbjct: 1582 ------EFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKA 1635
Query: 2893 XXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHG 3072
+ Q Q A D L +L + +
Sbjct: 1636 NAEAQKNIKRYQQQLKDVQSALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQA 1695
Query: 3073 VKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQL 3252
+ + + E +L + + LN + + KRKL +EL+ L E + + + +
Sbjct: 1696 DRGRRQAEQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDELLNEAKNSEEKA 1755
Query: 3253 MKR-------DEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELRED-METERNARNKA 3408
K +EL+ + + +++Q++++Q +DE + ++ + A K
Sbjct: 1756 KKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAESNALKGGKKAIQKL 1815
Query: 3409 EMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQ 3588
E RE+ ++L+ + D + + + ++ E++Q ++ K++++
Sbjct: 1816 EQRVRELESELDSEQRRHADAQKNLRKSERRIKELTFQSEEDRKNHERMQDLVD-KLQQK 1874
Query: 3589 KAKFSRQVEELHD----QIEQHKKQRSQLEKQQNQADQERADMAQEIA 3720
+ RQ+EE + + + +K + +LE+ + ERAD+A++ A
Sbjct: 1875 IKTYKRQIEEAEEIAALNLAKFRKAQQELEEAE-----ERADIAEQAA 1917
>gi|3041708|sp|P13540|MYH7_MESAU Myosin heavy chain, cardiac muscle
beta isoform (MyHC-beta)
gi|2119308|pir||I48153 myosin heavy chain beta, cardiac muscle
[similarity] - golden hamster
gi|402372|gb|AAA62313.1| beta-myosin heavy chain
gi|1581130|prf||2116354A beta myosin:SUBUNIT=heavy chain
Length = 1934
Score = 1145 bits (2961), Expect = 0.0
Identities = 666/1895 (35%), Positives = 1063/1895 (55%), Gaps = 17/1895 (0%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K +VPD E F+ I +V E + + VT+ D V + NPPKFDKIEDM+
Sbjct: 33 KKDVFVPDDKEEFVKAKIVSREGGKVTAE-TENGKTVTVKEDQVMQQNPPKFDKIEDMAM 91
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LT+L+E +VL+NLKD Y S +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E P
Sbjct: 92 LTFLHEPAVLYNLKDGYASWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPA 151
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIF+I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A A ++S
Sbjct: 152 HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIA-AIGDRS------ 204
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
K D G LE Q++QANP LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++
Sbjct: 205 -----KKDQTPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLAS 259
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYL-----LEGVDNYRFLVNR 960
A+IE YLLEKSRV+ Q + ER +HIFYQIL + +K E L +Y F+
Sbjct: 260 ADIETYLLEKSRVIFQLKAERDYHIFYQIL----SNKKPELLDMLLITNNPYDYAFIPQG 315
Query: 961 GITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQ 1140
T+ ++DD +E +T ++ ++GF +E +SI ++ A++ GN++F Q+++ +QA
Sbjct: 316 ETTVASIDDSEELMATDSAFDVLGFTSEEKNSIYKLTGAIMHFGNMKFKQKQREEQADRD 375
Query: 1141 DDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLF 1320
K +L+GL +L K PR+KVG E+V K QN +Q +A+ A+AK+ YE++F
Sbjct: 376 GTEEEDKSAYLMGLNSADLLKGMCHPRVKVGNEYVTKGQNVQQVSYAIGALAKSVYEKMF 435
Query: 1321 KWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFI 1500
W+VTRIN +L+ T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF+
Sbjct: 436 NWMVTRINATLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFV 494
Query: 1501 LEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKT 1680
LEQEEY++EGIEW FIDFG+DLQ IDLIEKPM ++++L+EEC+FPKA D +F KL
Sbjct: 495 LEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMRIMSILEEECMFPKATDMTFKAKLYDN 554
Query: 1681 H-NKHPKFIVP---DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDP 1848
H K F P + ++HF++VHYAG VDY+ WL KN DPLNE VVGL Q S+
Sbjct: 555 HLGKSNNFQKPRNVKGKQEAHFSLVHYAGTVDYNILGWLQKNKDPLNETVVGLYQKSSLK 614
Query: 1849 FVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVR 2028
++ ++ A +AG A + G + F+TVS LH+E L KLMT LR+T PHFVR
Sbjct: 615 LLSNLF--ANYAGADAPV--DKGKGKAKKGSSFQTVSVLHRENLNKLMTNLRSTHPHFVR 670
Query: 2029 CIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIP 2208
CIIPN K G +++ LV+ QLRCNGVLEGIRICR+GFPNR+ + +FR RY IL P IP
Sbjct: 671 CIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIP 730
Query: 2209 K-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQ 2385
+ FID ++ K++++LDID N Y+ G +KVFF+ G+L LEE RD +L+ +I QAQ
Sbjct: 731 EGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQ 790
Query: 2386 CRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRA 2565
RG LSR + N A++ ++NW W +L+ K+KPLL+ T+ E+
Sbjct: 791 SRGLLSRMEFKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMAT 850
Query: 2566 KDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTR 2745
+E K+ L K E +E E+K+ ++ E+ +Q Q+Q E +N A+ ++ +L
Sbjct: 851 MKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKN 910
Query: 2746 NQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNV 2925
+LE V +M +RL +RK + + DK
Sbjct: 911 KIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKDKHAT 970
Query: 2926 DQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQL 3105
+ + L E++ K+K +LE Q+
Sbjct: 971 ENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKSKVKLEQQV 1030
Query: 3106 HELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQL 3285
+LE L +E++ + +LE+ KRKL +L+ +++ + + ++L+ +L K+D EL
Sbjct: 1031 DDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDEKLKKKDFELNALN 1090
Query: 3286 TRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVL 3465
R ++E A + +QK+++++Q I+EL E++E ER AR K E R ++ +LE++ + L
Sbjct: 1091 ARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEI-SERL 1149
Query: 3466 DKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQH 3642
++ AT +Q M++K E E +R +E+ E + K + V EL +QI+
Sbjct: 1150 EEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 1209
Query: 3643 KKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHK 3822
++ + +LEK++++ E D+ + + ++A+++K + E + E ++ E+
Sbjct: 1210 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSV 1269
Query: 3823 RTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANI 4002
L Q + + E L+R +E+E + + R T + K
Sbjct: 1270 NDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNTLA 1329
Query: 4003 NRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN 4182
+ + + + L ++ EE +A L+ + A + R K E Q+ EEL +
Sbjct: 1330 HALQSARHDCDLLREQYEEETEAKAELQCVLSKANSEVAQWRTKYETDAIQRTEELEEAK 1389
Query: 4183 LRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFE 4353
+ + LQ E E + + ++K ++Q E+ED +++E A+ +K+Q+ F+
Sbjct: 1390 KKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFD 1449
Query: 4354 SQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQ 4533
+AE + +++ + ++ +E R T + L N + EHLE R ++LQ+E+
Sbjct: 1450 KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEIS 1509
Query: 4534 DSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKS 4713
D GK++HELEK ++ LEAE +++ +EE E +L+ E LR ++ +K+
Sbjct: 1510 DLTEQLGSTGKSIHELEKIRKQLEAEKMELQSALEEAEASLEHEEGNILRAQLEFNQIKA 1569
Query: 4714 ESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLE 4893
E +R ++ KD E E+ +R L+ + L+ L+ E R ++ A+ +KK+E + E+E QL
Sbjct: 1570 EIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLS 1629
Query: 4894 VANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLRE 5073
ANR+ E + QI+ ++A +A +D+ + +R+ ++AE E+LR
Sbjct: 1630 HANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA 1689
Query: 5074 ANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCEL 5244
E ++RK Q +K++++A ++Q C
Sbjct: 1690 VVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRN 1749
Query: 5245 AIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARA 5424
A +K +KA + +L E+ + E K+++E++ +D + ++ E E A +
Sbjct: 1750 AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKK 1809
Query: 5425 QMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEK 5604
Q+ LEA+V+ LE++L E + + + R+ E+R+ + T Q E++++ + ++L++K
Sbjct: 1810 QLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDK 1869
Query: 5605 SNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
LK + +RQ +EAE++ + +K R VQ E D+
Sbjct: 1870 LQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDE 1904
Score = 131 bits (330), Expect = 2e-28
Identities = 147/755 (19%), Positives = 311/755 (40%), Gaps = 44/755 (5%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + + D +E+ + +R +LE++ QE+ D+ ++ Q + AD ++
Sbjct: 845 EKEMATMKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERC 904
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ L + +E L + + DE L R ++ E A ++
Sbjct: 905 DQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVE 964
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ K A N+ + L +E A LDE + A L KE
Sbjct: 965 KD---------------------KHATENKVKNLTEEM-AGLDE------IIAKLTKEKK 996
Query: 4099 AARQGAGEARR--KAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQ 4272
A ++ +A +AEE L + + K + V+ L+ LE+ + + + ++K+K++
Sbjct: 997 ALQEAHQQALDDLQAEEDKVNTLTKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEG 1056
Query: 4273 EL---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETR 4443
+L ++S M+LEN + D + ++K FE R+ ++AL + + ++L++ + R
Sbjct: 1057 DLKLTQESIMDLENDK-QQLDEKLKKKDFELNALNARIEDEQALGSQ--LQKKLKELQAR 1113
Query: 4444 VLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDM 4623
+ L E++ + + +++R L +EL++ ++ G + + EAE M
Sbjct: 1114 IEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKM 1173
Query: 4624 RVQMEE----------------------LEDNLQIAEDARLRLEVTNQALKSESDRAISN 4737
R +EE L + + + + +LE K E D SN
Sbjct: 1174 RRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 1233
Query: 4738 KD------VEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
+ E+ R L Q+ + ++ E +R + S R K++ + GEL +QL+
Sbjct: 1234 MEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEK 1293
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA----DRKFRAVEAEREQL 5067
L + + + + EE +AK +A L+ A D E E E
Sbjct: 1294 EALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNTLAHALQSARHDCDLLREQYEEETEAK 1353
Query: 5068 REANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELA 5247
E L +A + + E K++L ++ + C
Sbjct: 1354 AELQCVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSL 1413
Query: 5248 IDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQ 5427
+ + Q ++E + D+ + ++++ ++ ++K K E +S +S ++ +
Sbjct: 1414 EKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELES-SQKE 1472
Query: 5428 MAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKS 5607
+L ++ L++ + R + L++ ++D T+Q ++ + +++ ++
Sbjct: 1473 ARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSTGKSIHELEKIRKQL 1532
Query: 5608 NLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ L+ L+EAE + E Q E + +
Sbjct: 1533 EAEKMELQSALEEAEASLEHEEGNILRAQLEFNQI 1567
Score = 55.8 bits (133), Expect = 1e-05
Identities = 63/340 (18%), Positives = 135/340 (39%), Gaps = 7/340 (2%)
Frame = +1
Query: 4747 EAEEKRRGLLKQIRDLENELENEKRGKSGA-------VSHRKKIENQIGELEQQLEVANR 4905
E EEK LL++ DL+ +++ E+ + A + ++ ++E ++ E+ ++LE
Sbjct: 871 ELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMTERLEDEEE 930
Query: 4906 LKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEG 5085
+ E + + EC E ++ +D+ L + ++ A E + + L E G
Sbjct: 931 MNAELTAKKR-------KLEDECSELKRDIDDLELTLAKVEKDKHATENKVKNLTEEMAG 983
Query: 5086 LMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRK 5265
L + + ++EK+ L+ Q + + K
Sbjct: 984 LDEIIAKL------------------TKEKKALQEAHQQALDDLQAEEDKVNTLTKSKVK 1025
Query: 5266 AQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEA 5445
+ Q++ + L E+ + E K+ LE + + I +LE+ Q
Sbjct: 1026 LEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQ----------- 1074
Query: 5446 KVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRN 5625
L+++L ++ + LN + EDE+ Q ++ L++
Sbjct: 1075 ----LDEKL--------------KKKDFELNALNARIEDEQALGSQLQKKLKE------- 1109
Query: 5626 LRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
L+ +++E E+E+ ERT V++ DL E+++ L
Sbjct: 1110 LQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 1149
>gi|38177589|gb|AAF00096.2| ventricular myosin heavy chain [Danio
rerio]
Length = 1938
Score = 1145 bits (2961), Expect = 0.0
Identities = 666/1929 (34%), Positives = 1070/1929 (54%), Gaps = 26/1929 (1%)
Frame = +1
Query: 1 MGDLQYLQVQRAAV----ADPATLAAWAQ----RKLCWVPDQNEGFLIGSIKRETNDEVL 156
MGD Q + AA +D L A + +K C+VPD +E ++ SI D+V
Sbjct: 1 MGDAQMAEFGAAASYLRKSDRERLEAQTRPFDMKKECFVPDPDEEYVKASIVSREGDKVT 60
Query: 157 VELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSG 336
V+ + + VT+ D+ NPPKFDKIEDM+ T+L+E +VL NLK+RY + +IYTYSG
Sbjct: 61 VQ-TEKRKTVTVKEADIHPQNPPKFDKIEDMAMFTFLHEPAVLFNLKERYAAWMIYTYSG 119
Query: 337 LFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGE 516
LFCV +NPYK LP+Y+++++ ++GKKR E PPHIF+I+D AY+ ML +RE+QSIL TGE
Sbjct: 120 LFCVAVNPYKWLPVYNQEVVVAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGE 179
Query: 517 SGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPIL 696
SGAGKT NTK+VIQY A +A K A + G LE Q++QANP L
Sbjct: 180 SGAGKTVNTKRVIQYFASIAAGGSAKKEGAEKK-------------GTLEDQIIQANPAL 226
Query: 697 EAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFY 876
EAFGN+KT++NDNSSRFGKFIRI+F SG ++ A+IE YLLEKSRV Q + ER +HIFY
Sbjct: 227 EAFGNAKTIRNDNSSRFGKFIRIHFGASGKLASADIETYLLEKSRVTFQLKAERDYHIFY 286
Query: 877 QILRGCSAKEKSEYL-----LEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFAD 1041
QIL ++ K E L +Y ++ T+ +++D +E +T + ++GF
Sbjct: 287 QIL----SQRKPELLEMLLITNNPYDYAYISQGETTVASINDGEELLATDEAFDVLGFTQ 342
Query: 1042 DEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPR 1221
+E + I +++ A++ GN++F Q+++ +QA KV +L+GL +L K PR
Sbjct: 343 EEKNGIYKLIGAIMHFGNMKFKQKQREEQAEADGTEDGDKVAYLMGLNSADLIKGLCHPR 402
Query: 1222 IKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDI 1401
+KVG E+V K QN +Q +A+ A+AK+ YE++F W+V RIN+SLD T + FIG+LDI
Sbjct: 403 VKVGNEWVTKGQNVQQVYYAIGALAKSVYEKMFLWMVVRINQSLD-TKQPRQYFIGVLDI 461
Query: 1402 AGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTID 1581
AGFEIFD N+FEQ+CIN+TNEKLQQ FN+ MF+LEQEEY++EGIEW+FIDFG+DLQ ID
Sbjct: 462 AGFEIFDFNTFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLQACID 521
Query: 1582 LIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPKFIVPDM---RSKSHFAVVHY 1749
LIEKPMG++++L+EEC+FPKA+D +F KL H K F P + +SHF++VHY
Sbjct: 522 LIEKPMGIMSILEEECMFPKASDSTFKAKLYDNHLGKSNNFQKPRAIKGKPESHFSLVHY 581
Query: 1750 AGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMR 1929
AG VDY+ + WL+KN DPLNE VVGL Q ST ++ ++ A +AG + G
Sbjct: 582 AGTVDYNINNWLVKNKDPLNETVVGLFQKSTVKLLSMLF--ANYAGTESDNGKGGKGGGS 639
Query: 1930 SRKG-MFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNG 2106
+KG F+TVS LH+E L KLMT LR+T PHFVRCIIPN K G + + LV+ QLRCNG
Sbjct: 640 KKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMENPLVMHQLRCNG 699
Query: 2107 VLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDGKESVRKMITALDIDTNLYR 2283
VLEGIRICR+GFPNR+ + +F+ RY IL P IP+ FID ++ K++ +LDID N Y+
Sbjct: 700 VLEGIRICRKGFPNRILYGDFKQRYRILNPAAIPEGQFIDSRKGAEKLLGSLDIDHNQYK 759
Query: 2284 IGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXN 2463
G +KVFF+ G+L LEE RD +L+ +I QA+ RG L+R + N
Sbjct: 760 FGHTKVFFKAGLLGQLEEMRDDRLSLIISGIQARSRGLLARVEFQKIVERRDALLVIQWN 819
Query: 2464 GLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKL 2643
A++ ++NW W +LF K+KPLL+ + E+ DE KE K E +E E+K+
Sbjct: 820 VRAFMGVKNWPWMKLFFKIKPLLKSAEAEKEMANMKDEFAKLKEAYAKSEARRKELEEKM 879
Query: 2644 DQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXX 2823
++ E+ +Q Q+Q E +N + ++ +L +LE ++ +RL
Sbjct: 880 VSLLQEKNDLQLQVQAEQDNLCDAEERCDQLIKNKIQLEAKAKELTERLEDEEEMNAELT 939
Query: 2824 XXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXX 3003
+RK + + +K + D
Sbjct: 940 AKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAALDDIIAKLTKEKK 999
Query: 3004 XXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLA 3183
L E++ KAK +LE Q+ +LE L +E++ + +LE+ KRKL
Sbjct: 1000 ALQEAHQQTLDDLQSEEDKVNTLTKAKAKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEG 1059
Query: 3184 ELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDE 3363
+L+ +++ L + ++L +L K+D E+ + ++E +QK+++++Q I+E
Sbjct: 1060 DLKLTQESLMDLENDKQQLEERLKKKDFEISQLNGKIEDEQTICIQLQKKLKELQARIEE 1119
Query: 3364 LREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDE-EVNATKR 3540
L E++E ER AR K E R ++ +LE+V + L++ AT Q M++K E E +R
Sbjct: 1120 LEEELEAERAARAKVEKQRADLARELEEV-SERLEEAGGATAAQIEMNKKREAEFQKLRR 1178
Query: 3541 AIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIA 3720
+E+ E + K + V EL +QI+ ++ + +LEK++++ E D+ +
Sbjct: 1179 DLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELRLELDDVVSNME 1238
Query: 3721 LLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEH 3900
+ ++A+++K + E + E + E Q + + E L+R EE++
Sbjct: 1239 HVVKTKANLEKMTRSLEDQMNEYKTKYEEGQRCINDFTMQKSKLQSENGELSRQLEEKDS 1298
Query: 3901 AFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAH 4080
+ + R T+ K A + + + + L ++ EE + +A
Sbjct: 1299 LVSQLTRSKMPYTQQIEDLKRQLEEETKAKSALAHAVQSARHDTDLLREQYEEEQEAKAE 1358
Query: 4081 LEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKER---ILQ 4251
L++ + A + R K E Q+ EEL + + + LQ+ E E + + +
Sbjct: 1359 LQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQETEEAVEAVNAKCSSLEK 1418
Query: 4252 SKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRD 4431
+K ++Q E+ED ++LE A+ +K+Q+ F+ ++E + +++ + ++ +E R
Sbjct: 1419 TKHRLQNEIEDLMVDLERSNAAAAALDKKQRNFDKVLSEWKQKFEESQAELESSQKEARC 1478
Query: 4432 RETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAE 4611
T + L N + +HLE R ++LQ+E+ D + GK++HELEK ++ LE E
Sbjct: 1479 LSTELFKLKNSYEEALDHLETMKRENKNLQEEISDLTEQLGEGGKSIHELEKMRKQLEQE 1538
Query: 4612 LNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRD 4791
++++ +EE E +L+ E LR ++ +K++ +R ++ KD E E+ +R L + I
Sbjct: 1539 KSEIQSALEEAEASLEHEEGKILRAQLEFSQIKADIERKLAEKDEEMEQSKRNLQRTIDT 1598
Query: 4792 LENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIE 4971
L++ LE+E R ++ A+ +KK+E + E+E QL ANR E + Q++
Sbjct: 1599 LQSSLESETRSRNEALRIKKKMEGDLNEMEIQLSQANRQAAEAQKQLKSVHAHMKDAQLQ 1658
Query: 4972 CEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARK---QXXXXXXXXXXXR 5142
+++ + ED+ +R+ ++AE E+LR A E + RK Q
Sbjct: 1659 LDDSLRTNEDLKENTAIVERRNNLLQAELEELRAALEQTERGRKLAEQELLDTSERVQLL 1718
Query: 5143 AKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLN 5322
+K++LE I+Q C A +K +KA + +L E+ +
Sbjct: 1719 HSQNTSLLNQKKKLETDISQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTS 1778
Query: 5323 QKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAA 5502
E K+++E++ +D + ++ E E A + Q+ LEA+V+ LE ++ E + + +
Sbjct: 1779 AHLERMKKNMEQTIKDLQHRLDEAEQIAMKGGKKQVQKLEARVRELECEVEAEQKRSSES 1838
Query: 5503 NRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKH 5682
+ R+ E+R+ + T Q E++++ + ++L++K LK + +R +E+E++ + K
Sbjct: 1839 VKGIRKYERRIKELTYQTEEDRKNIARLQDLVDKLQLKVKAYKRAAEESEEQANVHLGKF 1898
Query: 5683 RNVQREADD 5709
R +Q E D+
Sbjct: 1899 RKLQHELDE 1907
Score = 86.7 bits (213), Expect = 6e-15
Identities = 112/523 (21%), Positives = 221/523 (41%), Gaps = 21/523 (4%)
Frame = +1
Query: 4234 KERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAM 4413
K + L + ++E+ + E ++ ++ SE R+K+ E +M L A
Sbjct: 837 KIKPLLKSAEAEKEMANMKDEFAKLKEAYAKSEARRKELEEKMVSLLQEKNDLQLQVQAE 896
Query: 4414 SQELRDRETRVLSLL-NEVDI------MKEHLEESDRV-------RRSLQQELQDSISNK 4551
L D E R L+ N++ + + E LE+ + + +R L+ E + +
Sbjct: 897 QDNLCDAEERCDQLIKNKIQLEAKAKELTERLEDEEEMNAELTAKKRKLEDECSELKKDI 956
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQA----LKSES 4719
DD + ++EK K + E ++ ++ +M L+D + + L+ +Q L+SE
Sbjct: 957 DDLELTLAKVEKEKHATENKVKNLTEEMAALDDIIAKLTKEKKALQEAHQQTLDDLQSEE 1016
Query: 4720 DRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
D+ N +A+ K L +Q+ DLE LE EK+ + ++K+E + ++ L
Sbjct: 1017 DKV--NTLTKAKAK---LEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLTQESLMDL 1071
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREAN 5079
K++ + E + ED + + +K + ++A E+L E
Sbjct: 1072 ENDKQQLEERLK-------KKDFEISQLNGKIEDEQTICIQLQKKLKELQARIEELEEEL 1124
Query: 5080 EGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQ 5259
E AR + RA E RLE + ++ ++K+
Sbjct: 1125 EAERAARAKVEKQ-------RADLARELEEVSERLEE---------AGGATAAQIEMNKK 1168
Query: 5260 RKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITE-LESGAQSRARAQMAA 5436
R+A+ Q ++ DL E TL EA +L + D A++ E +++ + + + +
Sbjct: 1169 REAEFQ--KLRRDLE-EATLQH--EATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEK 1223
Query: 5437 LEAKVQYLEDQLNVEGQEKTAAN--RAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSN 5610
E +++ + N+E KT AN + R LE ++N+ ++E+ +R K
Sbjct: 1224 SELRLELDDVVSNMEHVVKTKANLEKMTRSLEDQMNEYKTKYEEGQRCINDFTMQKSKLQ 1283
Query: 5611 LKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTR 5739
+N L RQL+E + +S+ ++ +DL E+ T+
Sbjct: 1284 SENGELSRQLEEKDSLVSQLTRSKMPYTQQIEDLKRQLEEETK 1326
>gi|6093461|sp|P79293|MYH7_PIG Myosin heavy chain, cardiac muscle beta
isoform (MyHC-beta)
gi|11276950|pir||A59286 myosin heavy chain beta chain, cardiac - pig
gi|1698895|gb|AAB37320.1| beta-myosin heavy chain [Sus scrofa]
Length = 1935
Score = 1143 bits (2957), Expect = 0.0
Identities = 666/1896 (35%), Positives = 1057/1896 (55%), Gaps = 18/1896 (0%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K +VPD E F+ I +V E + + VT+ D V + NPPKFDKIEDM+
Sbjct: 34 KKDVYVPDDKEEFVKAKILSREGGKVTAE-TEHGKTVTVKEDQVLQQNPPKFDKIEDMAM 92
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LT+L+E +VL+NLK+RY S +IYTYSGLFCV INPYK LP+Y+ +++ ++GKKR + PP
Sbjct: 93 LTFLHEPAVLYNLKERYASWMIYTYSGLFCVTINPYKWLPVYNAEVVAAYRGKKRSDAPP 152
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAG-ATRNKSLNAAA 612
HIF+I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A R+K
Sbjct: 153 HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKEQTPG 212
Query: 613 QQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYIS 792
+ G LE Q++QANP LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++
Sbjct: 213 K-------------GTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLA 259
Query: 793 GANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYL-----LEGVDNYRFLVN 957
A+IE YLLEKSRV+ Q + ER +HIFYQIL + +K E L +Y F+
Sbjct: 260 SADIETYLLEKSRVIFQLKAERDYHIFYQIL----SNKKPELLDMLLITNNPYDYAFISQ 315
Query: 958 RGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAML 1137
T+ ++DD +E +T N+ ++GF +E +S+ ++ A++ GN++F +++ +QA
Sbjct: 316 GETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEP 375
Query: 1138 QDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERL 1317
K +L+GL +L K PR+KVG E+V K QN +Q +A A+AKA YE++
Sbjct: 376 DGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVMYATGALAKAVYEKM 435
Query: 1318 FKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMF 1497
F W+VTRIN +L+ T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF
Sbjct: 436 FNWMVTRINTTLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMF 494
Query: 1498 ILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQK 1677
+LEQEEY++EGIEW+FIDFG+DLQ IDLIEKPMG++++L+EEC+FPKA D +F KL
Sbjct: 495 VLEQEEYKKEGIEWEFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLYD 554
Query: 1678 TH-NKHPKFIVP---DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTD 1845
H K F P R ++HFA++HYAG VDY+ WL KN DPLNE VV L + S+
Sbjct: 555 NHLGKSNNFQKPRNIKGRPEAHFALIHYAGTVDYNIIGWLQKNKDPLNETVVDLYKKSSL 614
Query: 1846 PFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFV 2025
++ ++ A +AG A E G + F+TVS LH+E L KLMT LR+T PHFV
Sbjct: 615 KLLSNLF--ANYAG--ADTPVEKGKGKAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFV 670
Query: 2026 RCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVI 2205
RCIIPN K G I++ LV+ QLRCNGVLEGIRICR+GFPNR+ + +FR RY IL P I
Sbjct: 671 RCIIPNETKSPGVIDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAI 730
Query: 2206 PK-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQA 2382
P+ FID ++ K++ +LDID N Y+ G +KVFF+ G+L LEE RD +L+ +I QA
Sbjct: 731 PEGQFIDSRKGAEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQA 790
Query: 2383 QCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIR 2562
Q RG LSR + N A++ ++NW W +L+ K+KPLL+ T+ E+
Sbjct: 791 QSRGVLSRMEFKKLLERRDSLLIIQWNIRAFMSVKNWPWMKLYFKIKPLLESAETEKEMA 850
Query: 2563 AKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQT 2742
+E KE L K E +E E+K+ ++ E+ +Q Q+Q E +N ++ ++ +L
Sbjct: 851 TMKEEFGRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLSDSEERCDQLIK 910
Query: 2743 RNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTN 2922
+LE V +M +RL +R + + +K
Sbjct: 911 NKIQLEAKVKEMTERLEDEEEMNAELTAKKRNVEDECSELKRDIDDLELTLAKVEKEKHA 970
Query: 2923 VDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQ 3102
+ + L E++ KAK +LE
Sbjct: 971 TENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQH 1030
Query: 3103 LHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQ 3282
+ +L L +E++ + +LE+ KRKL +L+ +++ + + ++L+ +L K+D EL
Sbjct: 1031 VDDLAGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNAL 1090
Query: 3283 LTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDV 3462
R ++E A + +QK+++++Q I+EL E++E ER AR K E R ++ +LE++ +
Sbjct: 1091 NARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEI-SER 1149
Query: 3463 LDKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQ 3639
L++ AT +Q M++K E E +R +E+ E + K + V EL +QI+
Sbjct: 1150 LEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDN 1209
Query: 3640 HKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEH 3819
++ + +LEK++++ E D+ + + ++A+++K + E + E ++ E+
Sbjct: 1210 LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRS 1269
Query: 3820 KRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIAN 3999
L Q + + E L+R +E+E + + R T + K A
Sbjct: 1270 VNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNAL 1329
Query: 4000 INRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKK 4179
+ + + L ++ EE +A L++ + A + R K E Q+ EEL +
Sbjct: 1330 AHALQSARHAADLLREQYEEETETKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 1389
Query: 4180 NLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKF 4350
+ + LQ E E + + ++K ++Q E+ED +++E A+ +K+Q+ F
Sbjct: 1390 KKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNF 1449
Query: 4351 ESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQEL 4530
+ +AE + +++ + ++ +E R T + L N + EHLE S R ++LQ+E+
Sbjct: 1450 DKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETSKRENKNLQEEI 1509
Query: 4531 QDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALK 4710
D GK +HELEK ++ LEAE +++ +EE E +L+ E LR ++ +K
Sbjct: 1510 SDLTEQLGSSGKTIHELEKVRKQLEAEKLELQSALEESEASLEHEEGKILRAQLEFNQIK 1569
Query: 4711 SESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
+E +R ++ KD E E+ +R L+ + L+ L+ E R ++ A+ +KK+E + E+E QL
Sbjct: 1570 AEMERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQL 1629
Query: 4891 EVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLR 5070
ANR+ E + QI+ ++A +A +D+ + +R+ ++AE E+LR
Sbjct: 1630 SHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELR 1689
Query: 5071 EANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCE 5241
E ++RK Q +K+++EA ++Q
Sbjct: 1690 AVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMEADLSQLQTEVEEAVQESR 1749
Query: 5242 LAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRAR 5421
A +K +KA + +L E+ + E K+++E++ +D + ++ E E A +
Sbjct: 1750 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGK 1809
Query: 5422 AQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLE 5601
Q+ LEA+V+ LE++L E + + + R+ E+R+ + T Q E++++ + ++L++
Sbjct: 1810 KQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVD 1869
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
K LK + RQ +EAE++ + +K R VQ E D+
Sbjct: 1870 KLQLKVKAYNRQAEEAEEQANTNLSKFRKVQHELDE 1905
Score = 145 bits (365), Expect = 2e-32
Identities = 164/833 (19%), Positives = 359/833 (42%), Gaps = 25/833 (3%)
Frame = +1
Query: 3325 QKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLM 3504
+K+M M+ L+E +E K+E R+E+ ++ + + D + QD +
Sbjct: 846 EKEMATMKEEFGRLKEALE-------KSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 898
Query: 3505 SRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQA 3684
S +E + ++ + K + +V+E+ +++E ++ ++L ++
Sbjct: 899 SDSEERCD---------------QLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRNV 943
Query: 3685 DQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDE-------HKRTLIDQL 3843
+ E +++ ++I L+ + A ++K++ E + + +A DE K+ L +
Sbjct: 944 EDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAH 1003
Query: 3844 ERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLE 4023
+++ D+L + EE + + ++++ R+LE
Sbjct: 1004 QQALDDL-------QAEEDKVNTLTKAKVKLEQHVDDLAGSLEQEKKVRMDLERAKRKLE 1056
Query: 4024 DE----KNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRD 4191
+ + +++D + + + L L+K+ A AR + E+++ QL++ K+
Sbjct: 1057 GDLKLTQESIMDLENDKQQLDERLKKKDFELN--ALNARIEDEQALGSQLQKKLKELQAR 1114
Query: 4192 VEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEE 4371
+E L+++LE A+ ++ + + + +ELE+ S LE + + KK E++ +
Sbjct: 1115 IEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKM 1174
Query: 4372 RVAVQKALLDRDAMSQELRDRETRVLSLLNE-VDIMKEHLEESDRVRRSLQQELQDSISN 4548
R +++A L +A + LR + ++ L E +D ++ ++ ++ + + EL D SN
Sbjct: 1175 RRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 1234
Query: 4549 KDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRA 4728
+ K LEK R+LE ++N+ R + EE + ++ R +L+ N E R
Sbjct: 1235 MEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTEN----GELSRQ 1290
Query: 4729 ISNKDVEAEEKRRGLL---KQIRDLENELENEKRGKSGAVSHRKKIENQIGEL-----EQ 4884
+ K+ + RG L +Q+ DL+ +LE E + K+ A++H + +L E+
Sbjct: 1291 LDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKN-ALAHALQSARHAADLLREQYEE 1349
Query: 4885 QLEVANRLKEEYXXXXXXXXXXXXEYQIEC----EEARQAKEDIAALLREADRKFRAVEA 5052
+ E L+ +Y+ + EE +AK+ +A L++A+ AV A
Sbjct: 1350 ETETKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNA 1409
Query: 5053 EREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKI-AQXXXXXXXXQ 5229
+ L + R Q R+ + ++K+R KI A+ Q
Sbjct: 1410 KCSSLEKTKH-----RLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQ 1464
Query: 5230 SNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQ 5409
S E +Q + ++T+L + +++ ++ +R N++ + +I++L
Sbjct: 1465 SELE-------SSQKEARSLSTELFKLKNAYEESLEHLETSKRENKNLQEEISDLTEQLG 1517
Query: 5410 SRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAK 5589
S + +++ + QL E E L+ L ++ E E+ +A+
Sbjct: 1518 SSGKTIH-----ELEKVRKQLEAEKLE----------LQSALEESEASLEHEEGKILRAQ 1562
Query: 5590 ELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
LE + +K + R+L E ++EM + + H V LDA + E +
Sbjct: 1563 --LEFNQIK-AEMERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEAL 1612
Score = 69.7 bits (169), Expect = 8e-10
Identities = 96/476 (20%), Positives = 190/476 (39%), Gaps = 35/476 (7%)
Frame = +1
Query: 4420 ELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRS 4599
E + E + ++ E +KE LE+S+ R+ ELE+ S
Sbjct: 841 ESAETEKEMATMKEEFGRLKEALEKSEARRK---------------------ELEEKMVS 879
Query: 4600 LEAELNDMRVQMEELEDNLQIAE---DARLRLEVTNQA-LKSESDRAISNKDVEAE--EK 4761
L E ND+++Q++ +DNL +E D ++ ++ +A +K ++R +++ AE K
Sbjct: 880 LLQEKNDLQLQVQAEQDNLSDSEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAK 939
Query: 4762 RRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL----EVANRLKEEYXXX 4929
+R + + +L+ ++++ + + + EN++ L +++ E+ +L +E
Sbjct: 940 KRNVEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKAL 999
Query: 4930 XXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAER------EQLREANEGLM 5091
+ Q E ++ + L + D ++E E+ E+ + EG +
Sbjct: 1000 QEAHQQALDDLQAEEDKVNTLTKAKVKLEQHVDDLAGSLEQEKKVRMDLERAKRKLEGDL 1059
Query: 5092 QARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQ 5271
+ ++ + E L A+I Q K ++ Q
Sbjct: 1060 KLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQK-------KLKELQ 1112
Query: 5272 VQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKV 5451
++E++ +L ERT K E + L R + ++ E GA S EA+
Sbjct: 1113 ARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEE-AGGATSVQIEMNKKREAEF 1171
Query: 5452 QYLEDQLNVEGQEKTAANRA-ARRLEKRLNDTTQQFEDEKRANEQAKELLEK-------- 5604
Q + L +E T + A A L K+ D+ + ++ ++ K+ LEK
Sbjct: 1172 QKMRRDL----EEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLE 1227
Query: 5605 -----SNLK-----NRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
SN++ NL + ED+M+ R+K QR +DL +L E
Sbjct: 1228 LDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTE 1283
>gi|31235836|ref|XP_319308.1| ENSANGP00000012555 [Anopheles gambiae]
gi|30174792|gb|EAA13871.2| ENSANGP00000012555 [Anopheles gambiae str.
PEST]
Length = 1943
Score = 1142 bits (2954), Expect = 0.0
Identities = 680/1914 (35%), Positives = 1080/1914 (55%), Gaps = 29/1914 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K CWVP++ EG+++G IK T E++ + +D V + NPPK++K EDMS
Sbjct: 36 KKACWVPEEKEGYVLGEIKA-TKGELVTVALPGGETKDFKKDLVSQVNPPKYEKCEDMSN 94
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LTYLN+ASVLHNL+ RYY+ LIYTYSGLFCVVINPYK+ P+Y+ + ++GK+R+E+PP
Sbjct: 95 LTYLNDASVLHNLRQRYYAKLIYTYSGLFCVVINPYKRYPLYTNRCAKMYRGKRRNEVPP 154
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
H+FA++D AY +ML E+QS+L TGESGAGKTENTKKVI Y A + GA+ K NA +
Sbjct: 155 HLFAVSDGAYVNMLTNHENQSMLITGESGAGKTENTKKVIAYFATI-GASGKKDENAEKK 213
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
G LE Q++Q NP+LEAFGN+KTV+NDNSSRFGKFIRI+F SG ++G
Sbjct: 214 -------------GSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFTGSGKLAG 260
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGC--SAKEKSEYLLEGVDNYRFLVNRGIT 969
A+IE YLLEK+RV+ Q ERS+HIFYQI+ G KEK +L V +Y + T
Sbjct: 261 ADIETYLLEKARVISQQTLERSYHIFYQIMSGSVKGLKEKC-FLSNDVYDYMIIAQGKTT 319
Query: 970 LPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDR 1149
+PNVDD +E T + ++GF +E +I R+ SAV+ +G ++F Q+ + +QA
Sbjct: 320 IPNVDDGEEMGLTDEAFNVLGFTQEEKDNIYRITSAVMHMGRMQFKQKGREEQAEADGTE 379
Query: 1150 VIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWL 1329
+V LLG+ +L K L+PRIKVG EFV K QN++Q +V A+ K ++RLFKWL
Sbjct: 380 DGDRVAKLLGVGTDDLYKNLLKPRIKVGNEFVTKGQNKDQVTNSVGALCKGIFDRLFKWL 439
Query: 1330 VTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQ 1509
V + N++LD T ++ A FIG+LDIAGFEIFD N FEQ+CIN+TNEKLQQ FN+ MF+LEQ
Sbjct: 440 VKKCNETLD-TKQKRAQFIGVLDIAGFEIFDFNGFEQLCINFTNEKLQQFFNHHMFVLEQ 498
Query: 1510 EEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-N 1686
EEY++EGI W FIDFG+DL ++LIEKPMG+L++L+EE +FPKA D++F EKL H
Sbjct: 499 EEYKKEGINWAFIDFGMDLLACVELIEKPMGILSILEEESMFPKATDQTFAEKLMTNHLG 558
Query: 1687 KHPKFIVPDMRS----KSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFV 1854
K F+ P HFA+ HYAG V Y+ WL KN DPLN+ VV + ++ +
Sbjct: 559 KSAPFMKPRPPKPGIPAGHFAIGHYAGVVSYNITGWLEKNKDPLNDTVVDQFKKGSNALM 618
Query: 1855 AGIWKD--AEFAGICAAEMNETAFGMRSRKGM-FRTVSQLHKEQLTKLMTTLRNTSPHFV 2025
I+ D + A AA+ G R +KG F TVS +KEQL LMTTL++T PHFV
Sbjct: 619 VEIFADHPGQSADPAAAK------GGRGKKGAGFATVSSSYKEQLNNLMTTLKSTQPHFV 672
Query: 2026 RCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVI 2205
RCIIPN K +G ++++LV+ QL CNGVLEGIRICR+GFPNR+ + +F+ RY IL P +
Sbjct: 673 RCIIPNEMKTAGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKLRYLILAPAAM 732
Query: 2206 PKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQ 2385
+GK++ K A+ +D + YRIG +KVFFR GVL +EE RD +L+ ++ QA
Sbjct: 733 QAE-TEGKKAAEKCFEAIGLDPDSYRIGHTKVFFRAGVLGQMEEFRDERLSKIMSWMQAW 791
Query: 2386 CRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRA 2565
CRG+LSR+ + N YLKLR W WW+L+ KVKPLL V+R +D+I
Sbjct: 792 CRGYLSRKEFKKMQEQRVSLEIVQRNLRKYLKLRTWAWWKLWQKVKPLLNVSRVEDQIAK 851
Query: 2566 KDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTR 2745
+++ +E K E +E E +++ E+ + + L E E + +L +
Sbjct: 852 LEEKATKAQEAYEKEEKLRKELEALNSKLLAEKTALLDSLSGEKGALQEYQEKAAKLTAQ 911
Query: 2746 NQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNV 2925
+LE + D ++RL+ ++K + + DK +
Sbjct: 912 KNDLENQLRDTQERLAQEEDARNQLFQTKKKLEQEIGSQKKDAEDLELQIQKIEQDKASK 971
Query: 2926 DQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQL 3105
D + + +L E++ H K K +LE L
Sbjct: 972 DHQIRNLNDEIAHQDELINKLNKEKKMQGEVNQKTAEELQAAEDKVNHLNKVKAKLEQTL 1031
Query: 3106 HELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQL 3285
ELE L RE++ + ++E+ KRK+ +L+ +++ +A+ +EL ++++D+E+
Sbjct: 1032 DELEDSLEREKKLRGDVEKAKRKVEGDLKLTQEAVADLERNKKELEQTVLRKDKEISALS 1091
Query: 3286 TRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVL 3465
+ ++E + V +QKQ++++Q I+EL E++E ER AR KAE R ++ +LE++ G+ L
Sbjct: 1092 AKLEDEQSLVGKLQKQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEEL-GERL 1150
Query: 3466 DKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQH 3642
++ AT Q +L +++ E+ +R +E+ EG + + K + V E+ +Q++Q
Sbjct: 1151 EEAGGATSAQIELNKKREAELAKLRRDLEEANIQHEGTLANLRKKHNDAVAEMAEQVDQL 1210
Query: 3643 KKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHK 3822
K +++ EK++ Q E D L +A +K K + L E+Q+ L DE
Sbjct: 1211 NKLKTKAEKERTQYFAELNDARIGCDQLSNEKAAQEKIAKQLQHTLNEVQSKL---DETN 1267
Query: 3823 RTLIDQLERSRDEL----DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLK 3990
RTL D + S+ +L L R E+ E + + + + R +
Sbjct: 1268 RTLND-FDASKKKLSIENSDLLRQLEDAESQVSQLSKIKISLTQQLEDTKRLADEEARER 1326
Query: 3991 IANINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHAARQGAGEARRKAEE---SVNQQ 4158
+ + R LE + + L ++ +EEAEG + +++++ A A R K E + ++
Sbjct: 1327 ATLLGKFRNLEHDLDNLREQVEEEAEG-KGDIQRQLSKANAEAQLWRSKYESEGVARAEE 1385
Query: 4159 LEELRKK---NLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDS 4329
LEE ++K L + E + L + +A E+ +K+++ E+ED +E++ + +
Sbjct: 1386 LEEAKRKLQARLAEAEETIESLNQKCIALEK---TKQRLATEVEDLQLEVDRASSIANAA 1442
Query: 4330 EKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVR 4509
EK+QK F+ + E ++ V + DA +E R+ T + L + +E LE R
Sbjct: 1443 EKKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRREN 1502
Query: 4510 RSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLE 4689
++L E++D + + G+N+HE+EK+++ LEAE ++++ +EE E L+ E+ LR +
Sbjct: 1503 KNLADEVKDLLDQIGEGGRNIHEIEKSRKRLEAEKDELQAALEEAEAALEQEENKVLRAQ 1562
Query: 4690 VTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQI 4869
+ ++ E DR I K+ E E R+ + + ++ LE E +GK+ A+ +KK+E I
Sbjct: 1563 LELSQVRQEIDRRIQEKEEEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADI 1622
Query: 4870 GELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVE 5049
ELE L+ AN+ E + Q EE ++A++D L ++R+ A++
Sbjct: 1623 NELEIALDHANKANAEAQKNIKRYQQQLKDVQSALEEEQRARDDAREQLGISERRANALQ 1682
Query: 5050 AEREQ----LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXX 5217
E E+ L +A+ G QA ++ A+ I++ KR+LE+++
Sbjct: 1683 NELEESRTLLEQADRGRRQAEQELSDAHEQLNEVSAQNASIAA-AKRKLESELQTLHSDL 1741
Query: 5218 XXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELE 5397
+ + + +K +KA V ++ +L E+ Q E +++LE+ ++ + ++ E E
Sbjct: 1742 DELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAE 1801
Query: 5398 SGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRAN 5577
S A + + LE +V+ LE +L+ E + A + R+ E+R+ + T Q E++++ +
Sbjct: 1802 SNALKGGKKAIQKLEQRVRELESELDSEQRRHADAQKNLRKSERRIKELTFQSEEDRKNH 1861
Query: 5578 EQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQR---EADDLLDANEQ 5730
E+ ++L++K K + +RQ++EAE+ + K R Q+ EA++ D EQ
Sbjct: 1862 ERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADIAEQ 1915
Score = 155 bits (391), Expect = 1e-35
Identities = 186/948 (19%), Positives = 398/948 (41%), Gaps = 60/948 (6%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMK--- 3258
+LE + + ++ +E + + ELE KLLAE D L+ + G ++E + K
Sbjct: 851 KLEEKATKAQEAYEKEEKLRKELEALNSKLLAEKTALLDSLSGEKGALQEYQEKAAKLTA 910
Query: 3259 RDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQ 3438
+ +L++QL E A Q D + + + ++ +E E ++ K ++ Q
Sbjct: 911 QKNDLENQLRDTQERLA-------QEEDARNQLFQTKKKLEQEIGSQKK---DAEDLELQ 960
Query: 3439 LEKVKGDVLDKVDEATMLQDLMSRKDEEVN-----------ATKRAIEQIQHTME--GKI 3579
++K++ D K + L D ++ +DE +N ++ E++Q + +
Sbjct: 961 IQKIEQDKASKDHQIRNLNDEIAHQDELINKLNKEKKMQGEVNQKTAEELQAAEDKVNHL 1020
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKR 3759
+ KAK + ++EL D +E+ KK R +EK + + + + + L Q + AD+++ +
Sbjct: 1021 NKVKAKLEQTLDELEDSLEREKKLRGDVEKAKRKVEGD-------LKLTQEAVADLERNK 1073
Query: 3760 KIHEAHLM----EIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRL 3927
K E ++ EI A L+ E +++L+ +L++ EL R+ E EE A Q R
Sbjct: 1074 KELEQTVLRKDKEISA-LSAKLEDEQSLVGKLQKQIKELQA--RIEELEEEVEAERQAR- 1129
Query: 3928 ATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAAR 4107
+ + + AR+LE+ L E+ E G + E++ R
Sbjct: 1130 -----------------AKAEKQRADLARELEE-----LGERLEEAGGATSAQIELNKKR 1167
Query: 4108 QGAGEARRKAEESVNQQ----LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQE 4275
+ R+ E N Q L LRKK+ V + +Q+++ K + + + + E
Sbjct: 1168 EAELAKLRRDLEEANIQHEGTLANLRKKHNDAVAEMAEQVDQLNKLKTKAEKERTQYFAE 1227
Query: 4276 LEDSSM---ELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRV 4446
L D+ + +L N +A+ K+ + +++ + + L D DA ++L +
Sbjct: 1228 LNDARIGCDQLSNEKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSIENS-- 1285
Query: 4447 LSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMR 4626
LL +++ + + + +++ SL Q+L+D+ D+ + L R+LE +L+++R
Sbjct: 1286 -DLLRQLEDAESQVSQLSKIKISLTQQLEDTKRLADEEARERATLLGKFRNLEHDLDNLR 1344
Query: 4627 VQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENEL 4806
Q+EE + + + Q +S+ + + E EE +R L ++ + E +
Sbjct: 1345 EQVEEEAEGKGDIQRQLSKANAEAQLWRSKYESEGVARAEELEEAKRKLQARLAEAEETI 1404
Query: 4807 ENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEAR 4986
E+ + ++++ ++ +L+ +++ A+ + E++++ ++
Sbjct: 1405 ESLNQKCIALEKTKQRLATEVEDLQLEVDRASSIANAAEKKQKAFDKIIGEWKLKVDDLA 1464
Query: 4987 QAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISS 5166
+ R + ++ E+ +E E + + K +GG
Sbjct: 1465 AELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGRNIH 1524
Query: 5167 E---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEA 5337
E ++RLEA+ + ++ E +K +AQ++L Q+ ++ +R + +K E
Sbjct: 1525 EIEKSRKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEI--DRRIQEKEEE 1582
Query: 5338 EKQSLERSNRDYKAKITELESGAQSRARA--QMAALEAKVQYLEDQLNVEGQEKTAANRA 5511
+ + + R + LE+ A+ +A A LEA + LE L+ + A +
Sbjct: 1583 FENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQKN 1642
Query: 5512 ARRLEKRLNDTTQQFEDEKR----------------------------ANEQAKELLEKS 5607
+R +++L D E+E+R EQA ++
Sbjct: 1643 IKRYQQQLKDVQSALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRRQA 1702
Query: 5608 NLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
+ + QL+E + + R ++ E L ++L E N
Sbjct: 1703 EQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDELLNEAKN 1750
Score = 109 bits (272), Expect = 9e-22
Identities = 138/637 (21%), Positives = 266/637 (41%), Gaps = 88/637 (13%)
Frame = +1
Query: 3028 LTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDH 3207
L QL D E + K K L QL + ++ + E + ++ L R L +L++ ++
Sbjct: 1287 LLRQLEDAESQVSQLSKIKISLTQQLEDTKRLADEEARERATLLGKFRNLEHDLDNLREQ 1346
Query: 3208 LAEKMGKVEELNNQLMKRDEELQHQLTRYDEES-ANVTLMQKQMRDMQTTIDELREDMET 3384
+ E+ ++ QL K + E Q ++Y+ E A +++ R +Q + E E +E+
Sbjct: 1347 VEEEAEGKGDIQRQLSKANAEAQLWRSKYESEGVARAEELEEAKRKLQARLAEAEETIES 1406
Query: 3385 ERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRK----DEEVNATKRAIEQ 3552
E T++ + ++E D+ +VD A+ + + +K D+ + K ++
Sbjct: 1407 LNQKCIALEKTKQRLATEVE----DLQLEVDRASSIANAAEKKQKAFDKIIGEWKLKVDD 1462
Query: 3553 IQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQA 3732
+ ++ +E + +S ++ L E+ ++Q + ++ E D+ +I
Sbjct: 1463 LAAELDASQKECR-NYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGR 1521
Query: 3733 SRADIDKKRKIHEAHLMEIQANLAESD-----EHKRTLIDQLERS--RDELDHLNRVREE 3891
+ +I+K RK EA E+QA L E++ E + L QLE S R E+D + +EE
Sbjct: 1522 NIHEIEKSRKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEIDRRIQEKEE 1581
Query: 3892 E-EHAFANMQRRLATAXXXXXXXXXXXXXXTRLKI---ANINRARQLEDEKNALLDE--- 4050
E E+ N QR L + R+K A+IN D N E
Sbjct: 1582 EFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQK 1641
Query: 4051 -----KEEAEGLRAHLEKEIHA---ARQGAGEARRKAEESVNQ---------QLEELRKK 4179
+++ + +++ LE+E A AR+ G + R+A N+ Q + R++
Sbjct: 1642 NIKRYQQQLKDVQSALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRRQ 1701
Query: 4180 NLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKF--- 4350
+++ +QL E I +K+K++ EL+ +L+ + ++SE++ KK
Sbjct: 1702 AEQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDELLNEAKNSEEKAKKAMVD 1761
Query: 4351 ------ESQMAEERVAVQKALLDRDAMSQELRDR----------------------ETRV 4446
E + ++ Q+ L R A+ Q++++ E RV
Sbjct: 1762 AARLADELRAEQDHAQTQEKL--RKALEQQIKELQVRLDEAESNALKGGKKAIQKLEQRV 1819
Query: 4447 LSLLNEVDI-MKEHLE-------------------ESDRVRRSLQQELQDSISNK-DDFG 4563
L +E+D + H + E DR Q+L D + K +
Sbjct: 1820 RELESELDSEQRRHADAQKNLRKSERRIKELTFQSEEDRKNHERMQDLVDKLQQKIKTYK 1879
Query: 4564 KNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDA 4674
+ + E E+ A+ + ++EE E+ IAE A
Sbjct: 1880 RQIEEAEEIAALNLAKFRKAQQELEEAEERADIAEQA 1916
Score = 89.7 bits (221), Expect = 8e-16
Identities = 111/532 (20%), Positives = 233/532 (42%), Gaps = 11/532 (2%)
Frame = +1
Query: 4180 NLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQ 4359
N+ VE +LEE + + ++K+++ELE + +L + + DS +K
Sbjct: 841 NVSRVEDQIAKLEEKATKAQEAYEKEEKLRKELEALNSKLLAEKTALLDSLSGEK---GA 897
Query: 4360 MAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDS 4539
+ E + K ++ + +LRD + R L E D + + ++ L+QE+
Sbjct: 898 LQEYQEKAAKLTAQKNDLENQLRDTQER---LAQEEDARNQLFQ----TKKKLEQEIGSQ 950
Query: 4540 ISNKDDFGKNVHELEKAKRSLEAE---LNDMRVQMEELEDNLQIAEDARLRLEVTNQALK 4710
+ +D + ++E+ K S + + LND +EL + L ++ +++ EV +
Sbjct: 951 KKDAEDLELQIQKIEQDKASKDHQIRNLNDEIAHQDELINKLN--KEKKMQGEVNQKT-- 1006
Query: 4711 SESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
+E +A +K + + L + + +LE+ LE EK+ + ++K+E + ++ +
Sbjct: 1007 AEELQAAEDKVNHLNKVKAKLEQTLDELEDSLEREKKLRGDVEKAKRKVEGDLKLTQEAV 1066
Query: 4891 EVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLR 5070
R K+E + +I A+ ED +L+ + ++ + ++A E+L
Sbjct: 1067 ADLERNKKELEQTVLRK-----DKEISALSAKL--EDEQSLVGKLQKQIKELQARIEELE 1119
Query: 5071 EANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAI 5250
E E QAR AK ++ R LE + + EL
Sbjct: 1120 EEVEAERQAR--------------AKAEKQRADLARELEELGERLEEAGGATSAQIEL-- 1163
Query: 5251 DKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITE-------LESGAQ 5409
+K + +L ++ DL ++ T A +L + + D A++ E L++ A+
Sbjct: 1164 --NKKREAELAKLRRDLEEANIQHEGTLA---NLRKKHNDAVAEMAEQVDQLNKLKTKAE 1218
Query: 5410 SRARAQMAAL-EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQA 5586
A L +A++ DQL+ EK A + A++L+ LN+ + ++ R
Sbjct: 1219 KERTQYFAELNDARIGC--DQLS---NEKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDF 1273
Query: 5587 KELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
+K +++N +L RQL++AE ++S+ ++ ++ +D ++ RE
Sbjct: 1274 DASKKKLSIENSDLLRQLEDAESQVSQLSKIKISLTQQLEDTKRLADEEARE 1325
Score = 79.7 bits (195), Expect = 8e-13
Identities = 81/418 (19%), Positives = 183/418 (43%), Gaps = 25/418 (5%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L +Q+ E ++++ + + LE K +L A LE+++ L ++ KV +L + +E
Sbjct: 1512 LLDQIGEGGRNIHEIEKSRKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQE 1571
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ ++ +EE N ++ Q +D ++ +E E + +A ++++ A + ++
Sbjct: 1572 IDRRIQEKEEEFENTR------KNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINEL 1625
Query: 3451 KGDVLDKVDEATM-LQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+ LD ++A Q + R +++ + A+E+ Q + EQ R+ L +
Sbjct: 1626 E-IALDHANKANAEAQKNIKRYQQQLKDVQSALEEEQRARDDA-REQLGISERRANALQN 1683
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL-- 3801
++E+ + Q ++ + QA+QE +D +++ + A A I ++ E+ L + ++L
Sbjct: 1684 ELEESRTLLEQADRGRRQAEQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDE 1743
Query: 3802 ----AESDEHKRT--------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
A++ E K L D+L +D ++R+ E +Q RL A
Sbjct: 1744 LLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAESN 1803
Query: 3946 XXXXXXXXXXXTRLKIANIN------RARQLEDEKNALLDEKEEAE-GLRAHLEKEIHAA 4104
++ + + R + +KN E+ E ++ +++ H
Sbjct: 1804 ALKGGKKAIQKLEQRVRELESELDSEQRRHADAQKNLRKSERRIKELTFQSEEDRKNHER 1863
Query: 4105 RQGAGEARRKAEESVNQQLEELRK---KNLRDVEHLQKQLEESEVAKERILQSKKKIQ 4269
Q + ++ ++ +Q+EE + NL Q++LEE+E + Q+ K +
Sbjct: 1864 MQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADIAEQAATKFR 1921
Score = 53.9 bits (128), Expect = 5e-05
Identities = 62/408 (15%), Positives = 157/408 (38%), Gaps = 12/408 (2%)
Frame = +1
Query: 2533 QVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAE 2712
++ ++ + A+ DEL+A E + E + E K+ + +E + +++++ + + E
Sbjct: 1525 EIEKSRKRLEAEKDELQAALE---EAEAALEQEENKVLRAQLELSQVRQEIDRRIQEKEE 1581
Query: 2713 LDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXX 2892
+ + + ++ M+ L ++K + +
Sbjct: 1582 ------EFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKA 1635
Query: 2893 XXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHG 3072
+ Q Q A D L +L + +
Sbjct: 1636 NAEAQKNIKRYQQQLKDVQSALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQA 1695
Query: 3073 VKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQL 3252
+ + + E +L + + LN + + KRKL +EL+ L E + + + +
Sbjct: 1696 DRGRRQAEQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDELLNEAKNSEEKA 1755
Query: 3253 MKR-------DEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELRED-METERNARNKA 3408
K +EL+ + + +++Q++++Q +DE + ++ + A K
Sbjct: 1756 KKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAESNALKGGKKAIQKL 1815
Query: 3409 EMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQ 3588
E RE+ ++L+ + D + + + ++ E++Q ++ K++++
Sbjct: 1816 EQRVRELESELDSEQRRHADAQKNLRKSERRIKELTFQSEEDRKNHERMQDLVD-KLQQK 1874
Query: 3589 KAKFSRQVEELHD----QIEQHKKQRSQLEKQQNQADQERADMAQEIA 3720
+ RQ+EE + + + +K + +LE+ + ERAD+A++ A
Sbjct: 1875 IKTYKRQIEEAEEIAALNLAKFRKAQQELEEAE-----ERADIAEQAA 1917
>gi|50757621|ref|XP_415581.1| PREDICTED: similar to fast myosin heavy
chain isoform 3 [Gallus gallus]
Length = 2041
Score = 1140 bits (2950), Expect = 0.0
Identities = 661/1891 (34%), Positives = 1064/1891 (55%), Gaps = 17/1891 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V E F+ G+I+ +V V+ + +T+ D V NPPK+DKIEDM+ +T+L
Sbjct: 140 FVAHPKESFVKGTIQSRETGKVTVK-TEGGETLTVKEDQVFSMNPPKYDKIEDMAMMTHL 198
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 199 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVLAYRGKKRQEAPPHIFS 258
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A + K + +
Sbjct: 259 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAASGEKKKEEQSGKMQ-- 316
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 317 ---------GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIE 367
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPNV 981
YLLEKSRV Q + ERS+HIFYQI+ E + LL + +Y F+ IT+P++
Sbjct: 368 TYLLEKSRVTFQLKAERSYHIFYQIMSN-KKPELIDMLLITTNPYDYHFVSQGEITVPSI 426
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
DD +E +T +++ I+GF DE ++I ++ AV+ GNL+F Q+++ +QA V K
Sbjct: 427 DDQEELMATDSAIDILGFTADEKTAIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADK 486
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L+GL +L KA PR+KVG E+V K Q +Q AV A+AKA YE++F W+V RI
Sbjct: 487 AAYLMGLNSADLLKALCYPRVKVGNEYVTKGQTVQQVHNAVGALAKAVYEKMFLWMVVRI 546
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 547 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYK 605
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H K
Sbjct: 606 KEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSSN 665
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P ++++HF++VHYAG VDY+ WL KN DPLNE V+GL Q S+ +A ++
Sbjct: 666 FQKPKPAKGKAEAHFSLVHYAGTVDYNITGWLEKNKDPLNETVIGLYQKSSVKTLALLF- 724
Query: 1870 DAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHE 2049
A + G A G + + F+TVS L +E L KLMT LR+T PHFVRCIIPN
Sbjct: 725 -ATYGGADAEAGGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 783
Query: 2050 KKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDG 2226
K G + LVL QLRCNGVLEGIRICR+GFP+RV + +F+ RY++L IP+ FID
Sbjct: 784 KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRVLYADFKQRYKVLNASAIPEGQFIDS 843
Query: 2227 KESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSR 2406
K++ K+++++D+D Y+ G +KVFF+ G+L LEE RD KL LI QA+CRGFL R
Sbjct: 844 KKASEKLLSSIDVDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQARCRGFLMR 903
Query: 2407 RLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRA 2586
Y N +++ +++W W +LF K+KPLL+ ++ E+ +E
Sbjct: 904 VEYQRMVERRESIFCIQYNVRSFMNVKHWPWMKLFFKIKPLLKSAESEKEMANMKEEFEK 963
Query: 2587 TKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYI 2766
TKE L K E +E E+K+ +++ E+ +Q Q+Q E+++ A+ ++ +L +LE
Sbjct: 964 TKEELAKSEAKRKELEEKMVKLVQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAK 1023
Query: 2767 VNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXX 2946
+ ++ +R +RK + + +K +
Sbjct: 1024 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 1083
Query: 2947 XXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDL 3126
+ L E++ KAK +LE Q+ +LE L
Sbjct: 1084 TEEMAALDETIVKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSL 1143
Query: 3127 NRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEES 3306
+E++ + +LE+ KRKL +L+ + D + + ++L+ +L K+D E+ ++ ++E
Sbjct: 1144 EQEKKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQ 1203
Query: 3307 ANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT 3486
A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L++ AT
Sbjct: 1204 ALGMQLQKKIKELQARIEELEEEIEAERTSRAKAEKHRADLSRELEEI-SERLEEAGGAT 1262
Query: 3487 MLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQL 3663
Q D+ +++ E +R +E+ E + K + EL +QI+ ++ + +L
Sbjct: 1263 AAQIDMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKL 1322
Query: 3664 EKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLID-- 3837
EK++++ E D+A + + ++A+++K + E L EI+ + +EH+R + D
Sbjct: 1323 EKEKSELKMEIDDLASNMESVSKAKANLEKMCRTLEDQLSEIK---TKEEEHQRMINDLN 1379
Query: 3838 -QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRAR 4014
Q R + E +R EE++ + + R + K A + +
Sbjct: 1380 TQRARLQTEAGEYSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKNALAHALQ 1439
Query: 4015 QLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDV 4194
+ + L ++ EE + + L++ + A + R K E Q+ EEL + +
Sbjct: 1440 SARHDCDLLREQYEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA 1499
Query: 4195 EHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMA 4365
+ LQ E E + + ++K+++Q E+ED +++E A+ +K+QK F+ +A
Sbjct: 1500 QRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERANAACAALDKKQKNFDKILA 1559
Query: 4366 EERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSIS 4545
E + ++ + +A +E R T + + N + +HLE R ++LQQE+ D
Sbjct: 1560 EWKQKYEETQAELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEISDLTE 1619
Query: 4546 NKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDR 4725
+ GK +HELEK K+ +E E ++++ +EE E +L+ E LRL++ +KSE DR
Sbjct: 1620 QIAEGGKAIHELEKVKKQIEQEKSEIQAALEEAEASLEHEEGKILRLQLELNQVKSEIDR 1679
Query: 4726 AISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANR 4905
I+ KD E ++ +R L+ + L++ L+ E R ++ A+ +KK+E + E+E QL ANR
Sbjct: 1680 KIAEKDEEIDQLKRNHLRIVESLQSSLDAEIRSRNEALRLKKKMEGDLNEMEIQLSHANR 1739
Query: 4906 LKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEG 5085
+ E + QI ++A + +ED+ + +R+ ++AE E+LR A E
Sbjct: 1740 VAAEAQKNLRNTQAVLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEIEELRAALEQ 1799
Query: 5086 LMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDK 5256
++RK Q K++LE IAQ A +K
Sbjct: 1800 TERSRKVAEQELMDASERVQLLHTQNTSLINTKKKLETDIAQIQSEMEDTIQEARNAEEK 1859
Query: 5257 QRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAA 5436
+KA + +L E+ + E K++L+++ +D + ++ E E A + Q+
Sbjct: 1860 AKKAITDAAMMAEELKKEQDTSAHLERMKKNLDQTVKDLQHRLDEAEQLALKGGKKQIQK 1919
Query: 5437 LEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLK 5616
LEA+V+ LE +++ E + A + R+ E+R+ + T Q E++++ + ++L++K +K
Sbjct: 1920 LEARVRELEGEVDAEQKRSAEAVKGVRKYERRVKELTYQSEEDRKNILRLQDLVDKLQMK 1979
Query: 5617 NRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
++ +RQ +EAE+ + +K R +Q E ++
Sbjct: 1980 VKSYKRQAEEAEELSNVNLSKFRKIQHELEE 2010
Score = 165 bits (418), Expect = 1e-38
Identities = 188/929 (20%), Positives = 390/929 (41%), Gaps = 43/929 (4%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + + +++L + + ELE+ KL+ E D + + A+ + EE +
Sbjct: 952 KEMANMKEEFEKTKEELAKSEAKRKELEEKMVKLVQEKNDLQLQVQAEADSLADAEERCD 1011
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE N L K+ R ++ EL++D++ E
Sbjct: 1012 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKDIDD-------LE 1063
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E L + + + +E A + A +Q ++ +
Sbjct: 1064 LTLAKVEKEKHATENKVKNLTEEMAALDETIVKLTKEKKALQEAHQQTLDDLQAEEDKVN 1123
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK 3753
+ + K K +QV++L +EQ KK R LE+ + + + + I L+ + +D+
Sbjct: 1124 TLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDE 1183
Query: 3754 KRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLAT 3933
K K + + +IQ+ + E ++ L QL++ EL R+ E EE A R
Sbjct: 1184 KLKKKDFEISQIQSKI----EDEQALGMQLQKKIKELQ--ARIEELEEEIEAERTSRAKA 1237
Query: 3934 AXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQG 4113
RL+ A A Q++ +++K EAE
Sbjct: 1238 EKHRADLSRELEEISERLEEAGGATAAQID------MNKKREAE---------------- 1275
Query: 4114 AGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELED 4284
+ RR EE+ Q LRKK+ L +Q++ + K+++ + K +++ E++D
Sbjct: 1276 FQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDD 1335
Query: 4285 SSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNE 4464
+ +E+V + + EK + E Q++E + + + + D T+ L E
Sbjct: 1336 LASNMESVSKAKANLEKMCRTLEDQLSEIKT-------KEEEHQRMINDLNTQRARLQTE 1388
Query: 4465 VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEEL 4644
+EE D + L + Q ++ +++ E KAK +L L R + L
Sbjct: 1389 AGEYSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKNALAHALQSARHDCDLL 1448
Query: 4645 EDNLQIAEDARLRL---------EVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLE 4797
+ + ++A+ L EV K E+D AI + E EE ++ L ++++D E
Sbjct: 1449 REQYEEEQEAKGELQRALSKANSEVAQWRTKYETD-AIQRTE-ELEEAKKKLAQRLQDAE 1506
Query: 4798 NELENEKRGKSGAVSHRKKIENQIGELEQQLEVAN-------RLKEEYXXXXXXXXXXXX 4956
+E + +++++N++ +L +E AN + ++ +
Sbjct: 1507 EHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERANAACAALDKKQKNFDKILAEWKQKYE 1566
Query: 4957 EYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXX 5136
E Q E E +++ ++ L + + E L+ N+ L Q
Sbjct: 1567 ETQAELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEISDLTEQI----- 1621
Query: 5137 XRAKGGGISSE---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSM 5307
A+GG E K+++E + ++ +++ E K + Q++L Q+ ++
Sbjct: 1622 --AEGGKAIHELEKVKKQIEQEKSEIQAALEEAEASLEHEEGKILRLQLELNQVKSE--- 1676
Query: 5308 ERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQ 5487
+++K + + +++ R++ + L+S + R++ AL K + +E LN
Sbjct: 1677 ---IDRKIAEKDEEIDQLKRNHLRIVESLQSSLDAEIRSRNEALRLK-KKMEGDLNEMEI 1732
Query: 5488 EKTAANRAARRLEKR-------LNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDE 5646
+ + ANR A +K L DT +D R E KE + + L+ +++E
Sbjct: 1733 QLSHANRVAAEAQKNLRNTQAVLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEIEE 1792
Query: 5647 AEDEMSRERTKHRNVQREADDLLDANEQL 5733
+ + + ++E L+DA+E++
Sbjct: 1793 LRAALEQTERSRKVAEQE---LMDASERV 1818
Score = 140 bits (353), Expect = 4e-31
Identities = 170/887 (19%), Positives = 365/887 (40%), Gaps = 82/887 (9%)
Frame = +1
Query: 3325 QKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVD-EATMLQDL 3501
+K+M +M+ ++ +E++ R + E E + +L + K D+ +V EA L D
Sbjct: 951 EKEMANMKEEFEKTKEELAKSEAKRKELE----EKMVKLVQEKNDLQLQVQAEADSLADA 1006
Query: 3502 MSRKDEEVNATKRAIEQIQHTMEGKIEEQ---------KAKFSRQVEELHDQIEQHKKQR 3654
R D+ + + +I+ E +E+ K K + EL I+ +
Sbjct: 1007 EERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTL 1066
Query: 3655 SQLEKQQNQADQERADMAQEIALLQASRADIDKKRK-IHEAHLMEIQANLAESDEHKRTL 3831
+++EK+++ + + ++ +E+A L + + K++K + EAH + AE D+ TL
Sbjct: 1067 AKVEKEKHATENKVKNLTEEMAALDETIVKLTKEKKALQEAHQQTLDDLQAEEDK-VNTL 1125
Query: 3832 IDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRA 4011
+ ++D L E+E+ +++R LK+A+ +
Sbjct: 1126 TKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGD-------------LKLAH-DSI 1171
Query: 4012 RQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRD 4191
LE++K L ++ ++ + + ++ +I + E+++ QL++ K+
Sbjct: 1172 MDLENDKQQLDEKLKKKDFEISQIQSKI------------EDEQALGMQLQKKIKELQAR 1219
Query: 4192 VEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEE 4371
+E L++++E ++ + + + + +ELE+ S LE + KK E++ +
Sbjct: 1220 IEELEEEIEAERTSRAKAEKHRADLSRELEEISERLEEAGGATAAQIDMNKKREAEFQKM 1279
Query: 4372 RVAVQKALLDRDAMSQELRDRETRVLSLLNE-VDIMKEHLEESDRVRRSLQQELQDSISN 4548
R +++A L +A + LR + + L E +D ++ ++ ++ + L+ E+ D SN
Sbjct: 1280 RRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASN 1339
Query: 4549 KDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRA 4728
+ K LEK R+LE +L++++ + EE + + R RL Q E R
Sbjct: 1340 MESVSKAKANLEKMCRTLEDQLSEIKTKEEEHQRMINDLNTQRARL----QTEAGEYSRQ 1395
Query: 4729 ISNKDVEAEEKRRG---LLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
+ KD + RG +QI +L+ LE E + K+ + + L +Q E
Sbjct: 1396 VEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKNALAHALQSARHDCDLLREQYEEE 1455
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIE--------CEEARQAKEDIAALLREADRKFRAVEAE 5055
K E +++ + EE +AK+ +A L++A+ AV A+
Sbjct: 1456 QEAKGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAK 1515
Query: 5056 -------REQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXX 5214
+++L+ E LM ++ + I +E K++ E A+
Sbjct: 1516 CASLEKTKQRLQNEVEDLMIDVERANAACAALDKKQKNFDKILAEWKQKYEETQAELEAS 1575
Query: 5215 XXXXQS-----------------NCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEK 5343
+S + E + + Q ++ +T ++ + E K
Sbjct: 1576 QKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKAIHELEKVK 1635
Query: 5344 QSLERSNRDYKAKITELESGAQSRA----RAQMAALEAK--------------------- 5448
+ +E+ + +A + E E+ + R Q+ + K
Sbjct: 1636 KQIEQEKSEIQAALEEAEASLEHEEGKILRLQLELNQVKSEIDRKIAEKDEEIDQLKRNH 1695
Query: 5449 ---VQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKN 5619
V+ L+ L+ E + + A R +++E LN+ Q R +A++ L +
Sbjct: 1696 LRIVESLQSSLDAEIRSRNEALRLKKKMEGDLNEMEIQLSHANRVAAEAQKNLRNTQAVL 1755
Query: 5620 RNLRRQLDEA-------EDEMSRERTKHRNVQREADDLLDANEQLTR 5739
++ + LD+A +++++ + +Q E ++L A EQ R
Sbjct: 1756 KDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEIEELRAALEQTER 1802
Score = 137 bits (346), Expect = 2e-30
Identities = 177/904 (19%), Positives = 361/904 (39%), Gaps = 135/904 (14%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ + ++ +E+D ++ ++KL + E + IQ +++ E +L LQ
Sbjct: 1158 RKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQ 1217
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + +R S R ++E + + +
Sbjct: 1218 ARIEELEEEIE--AERTSRAKAEKHRADLSR--ELEEISERLEEAGGATAAQIDMNKKRE 1273
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K L+
Sbjct: 1274 AEFQKMRRDLEEATLQHEATAAALRKKHADSTAELG---EQIDNLQRVKQKLEKEKSELK 1330
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K+ LE+ R L +L + K E + +LN Q + E
Sbjct: 1331 MEIDDLASNMESVSKAKANLEKMCRTLEDQLSEIKTKEEEHQRMINDLNTQRARLQTEAG 1390
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ +E+ A ++ + + + I+EL+ +E E A+N + + ++
Sbjct: 1391 EYSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKNALAHALQSARHDCDLLRE 1450
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
++ + LQ +S+ + EV TK + IQ T E +EE K K ++++++ +
Sbjct: 1451 QYEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQDAEEH 1508
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME-------I 3789
+E + + LEK + + E D+ ++ A+ A +DKK+K + L E
Sbjct: 1509 VEAVNAKCASLEKTKQRLQNEVEDLMIDVERANAACAALDKKQKNFDKILAEWKQKYEET 1568
Query: 3790 QANLAESDEHKRTLIDQLERSR----DELDHLNRVREEEEHAFANMQRRLATAXXXXXXX 3957
QA L S + R+L +L + + + LDHL ++ E + N+Q+ ++
Sbjct: 1569 QAELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENK----NLQQEISDLTEQIAEG 1624
Query: 3958 XXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKA 4137
++K +Q+E EK+ + EEAE H E +I + + + +
Sbjct: 1625 GKAIHELEKVK-------KQIEQEKSEIQAALEEAEASLEHEEGKILRLQLELNQVKSEI 1677
Query: 4138 EESV---NQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE-- 4302
+ + ++++++L++ +LR VE LQ L+ ++ L+ KKK++ +L + ++L
Sbjct: 1678 DRKIAEKDEEIDQLKRNHLRIVESLQSSLDAEIRSRNEALRLKKKMEGDLNEMEIQLSHA 1737
Query: 4303 ------------NVRASHRDS---------------------EKRQKKFESQMAEERVAV 4383
N +A +D+ E+R ++++ E R A+
Sbjct: 1738 NRVAAEAQKNLRNTQAVLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEIEELRAAL 1797
Query: 4384 QKALLDRDAMSQELRDRETRV-------LSLLN-----EVDI------MKEHLEESDRVR 4509
++ R QEL D RV SL+N E DI M++ ++E+
Sbjct: 1798 EQTERSRKVAEQELMDASERVQLLHTQNTSLINTKKKLETDIAQIQSEMEDTIQEARNAE 1857
Query: 4510 RSLQQELQDSISNKDDFGKNVH---ELEKAKRSLEAELNDMRVQMEELED-NLQIAEDAR 4677
++ + D+ ++ K LE+ K++L+ + D++ +++E E L+ +
Sbjct: 1858 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLDQTVKDLQHRLDEAEQLALKGGKKQI 1917
Query: 4678 LRLEVTNQALKSESD-----------------RAISNKDVEAEEKRRGLLK--------- 4779
+LE + L+ E D R + ++EE R+ +L+
Sbjct: 1918 QKLEARVRELEGEVDAEQKRSAEAVKGVRKYERRVKELTYQSEEDRKNILRLQDLVDKLQ 1977
Query: 4780 ----------------------QIRDLENELE-------------NEKRGKSGAVSHRKK 4854
+ R +++ELE N+ R KS H KK
Sbjct: 1978 MKVKSYKRQAEEAEELSNVNLSKFRKIQHELEEAEERADIAESQVNKLRVKSREF-HSKK 2036
Query: 4855 IENQ 4866
IE +
Sbjct: 2037 IEEE 2040
Score = 98.2 bits (243), Expect = 2e-18
Identities = 117/616 (18%), Positives = 255/616 (40%), Gaps = 48/616 (7%)
Frame = +1
Query: 3055 ERAKHGVKAKGRLENQLHELEQDLNRER--------QYKSELEQHKRKLLAELEDSKDHL 3210
E+ + +AKG L+ L + ++ + R Q ELE+ K+KL L+D+++H+
Sbjct: 1450 EQYEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHV 1509
Query: 3211 AEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETER 3390
K L + E++ + + +A + K+ ++ + E ++ E +
Sbjct: 1510 EAVNAKCASLEKTKQRLQNEVEDLMIDVERANAACAALDKKQKNFDKILAEWKQKYEETQ 1569
Query: 3391 NARNKAEMTRREVVAQLEKVKGDVLDKVD-------EATMLQDLMSRKDEEVNATKRAIE 3549
++ R + +L K+K + +D E LQ +S E++ +AI
Sbjct: 1570 AELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKAIH 1629
Query: 3550 QIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQ 3729
+++ + +IE++K++ +EE +E + + +L+ + NQ ++++ ++IA
Sbjct: 1630 ELEKVKK-QIEQEKSEIQAALEEAEASLEHEEGKILRLQLELNQV---KSEIDRKIA--- 1682
Query: 3730 ASRADIDKKRKIHEAHLMEIQANLA-------ESDEHKRTLIDQLERSRDELDHLNRVRE 3888
+ID+ ++ H + +Q++L E+ K+ + L +L H NRV
Sbjct: 1683 EKDEEIDQLKRNHLRIVESLQSSLDAEIRSRNEALRLKKKMEGDLNEMEIQLSHANRVAA 1742
Query: 3889 EEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEG 4068
E + N Q L RA L+ E L E+ E
Sbjct: 1743 EAQKNLRNTQAVLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEIEELRAALEQTER 1802
Query: 4069 LRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERIL 4248
R E+E+ A + R + + N L +KK D+ +Q ++E++ +
Sbjct: 1803 SRKVAEQELMDASE-----RVQLLHTQNTSLINTKKKLETDIAQIQSEMEDTI---QEAR 1854
Query: 4249 QSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMS---- 4416
+++K ++ + D++M E ++ +D+ ++ + + + +Q L + + ++
Sbjct: 1855 NAEEKAKKAITDAAMMAEELK-KEQDTSAHLERMKKNLDQTVKDLQHRLDEAEQLALKGG 1913
Query: 4417 -QELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAK 4593
++++ E RV L EVD ++ E+ + R ++ +++ ++ KN+ L+
Sbjct: 1914 KKQIQKLEARVRELEGEVDAEQKRSAEAVKGVRKYERRVKELTYQSEEDRKNILRLQDLV 1973
Query: 4594 RSLEAELNDMRVQ---------------------MEELEDNLQIAEDARLRLEVTNQALK 4710
L+ ++ + Q +EE E+ IAE +L V
Sbjct: 1974 DKLQMKVKSYKRQAEEAEELSNVNLSKFRKIQHELEEAEERADIAESQVNKLRV------ 2027
Query: 4711 SESDRAISNKDVEAEE 4758
R +K +E EE
Sbjct: 2028 --KSREFHSKKIEEEE 2041
Score = 73.9 bits (180), Expect = 4e-11
Identities = 98/457 (21%), Positives = 197/457 (42%), Gaps = 40/457 (8%)
Frame = +1
Query: 4492 ESDRVRRSLQQELQDSISNKDDFGKNV---HELEKAKRSLEAELNDMRVQMEELEDNLQI 4662
ES++ ++++E + + K++ K+ ELE+ L E ND+++Q++ D+L
Sbjct: 949 ESEKEMANMKEEFEKT---KEELAKSEAKRKELEEKMVKLVQEKNDLQLQVQAEADSLAD 1005
Query: 4663 AE---DARLRLEVTNQA-LKSESDRAISNKDVEAE--EKRRGLLKQIRDLENELENEKRG 4824
AE D ++ ++ +A +K ++RA +++ AE K+R L + +L+ ++++ +
Sbjct: 1006 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 1065
Query: 4825 KSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDI 5004
+ + EN++ L +++ +E E + + QA+ED
Sbjct: 1066 LAKVEKEKHATENKVKNLTEEMAAL----DETIVKLTKEKKALQEAHQQTLDDLQAEEDK 1121
Query: 5005 AALLREADRKFRA----VEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEE 5172
L +A K +E EQ ++ L +A+++ +
Sbjct: 1122 VNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAHDSIMD----LEND 1177
Query: 5173 KRRLEAKIAQXXXXXXXXQSNCE----LAIDKQRKA---QVQLEQITTDLSMERTLNQKT 5331
K++L+ K+ + QS E L + Q+K Q ++E++ ++ ERT K
Sbjct: 1178 KQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERTSRAKA 1237
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRARAQM-AALEAKVQYLEDQLNVEGQEKTAANR 5508
E + L R + ++ E +G + A+ M EA+ Q + L +E T +
Sbjct: 1238 EKHRADLSRELEEISERLEE--AGGATAAQIDMNKKREAEFQKMRRDL----EEATLQHE 1291
Query: 5509 A-ARRLEKRLNDTTQQFEDEKRANEQAKELLEK-------------SNLKN-----RNLR 5631
A A L K+ D+T + ++ ++ K+ LEK SN+++ NL
Sbjct: 1292 ATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMESVSKAKANLE 1351
Query: 5632 RQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
+ ED++S +TK QR +DL +L E
Sbjct: 1352 KMCRTLEDQLSEIKTKEEEHQRMINDLNTQRARLQTE 1388
Score = 51.6 bits (122), Expect = 2e-04
Identities = 76/349 (21%), Positives = 133/349 (37%), Gaps = 51/349 (14%)
Frame = +1
Query: 4852 KIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADR 5031
KI+ + E + E+AN +KEE+ + ++ +E + L++E +
Sbjct: 940 KIKPLLKSAESEKEMAN-MKEEFEKTKEELAKSEAK-------RKELEEKMVKLVQEKND 991
Query: 5032 KFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXX 5211
V+AE + L +A E Q K K +LEAKI +
Sbjct: 992 LQLQVQAEADSLADAEERCDQLIKT----------------------KIQLEAKIKEVTE 1029
Query: 5212 XXXXXQS-NCELAIDKQRKAQVQLEQITTDLS-MERTLNQKTEAEKQSLERSNRDYKAKI 5385
+ N EL K+RK + + ++ D+ +E TL K E EK + E ++ ++
Sbjct: 1030 RAEDEEEINAELTA-KKRKLEDECSELKKDIDDLELTL-AKVEKEKHATENKVKNLTEEM 1087
Query: 5386 TELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDE 5565
L+ + + A EA Q L+D L E + +A +LE++++D E E
Sbjct: 1088 AALDETIVKLTKEKKALQEAHQQTLDD-LQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQE 1146
Query: 5566 KRAN---EQAKELLE----------------KSNL------------------------- 5613
K+ E+AK LE K L
Sbjct: 1147 KKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALG 1206
Query: 5614 -----KNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
K + L+ +++E E+E+ ERT ++ DL E+++ L
Sbjct: 1207 MQLQKKIKELQARIEELEEEIEAERTSRAKAEKHRADLSRELEEISERL 1255
>gi|13537551|dbj|BAB40711.1| myosin [Mizuhopecten yessoensis]
Length = 1945
Score = 1140 bits (2948), Expect = 0.0
Identities = 657/1920 (34%), Positives = 1069/1920 (55%), Gaps = 19/1920 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
D Q L V R + T A + +K CWVPD EGF I+ +E+ V++ +
Sbjct: 9 DFQDLAVDRKKLLKEQT-APFDGKKNCWVPDTKEGFAAAEIQSSKGEEIAVKITSDNSTR 67
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
T+ +DD+Q+ NPPKF+K+EDM+ +TYLNEASVLHNL RY +IYTYS LFC+ +NPY+
Sbjct: 68 TVKKDDIQEMNPPKFEKLEDMANMTYLNEASVLHNLSARYTCGMIYTYSRLFCIAVNPYR 127
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
+LPIY++ +I +++GK++ E+PPH+F++AD AY++M+ +RE+QS L TGESGAGKTENTK
Sbjct: 128 RLPIYTDSVISKYRGKRKTEIPPHLFSVADNAYQNMVTDRENQSCLITGESGAGKTENTK 187
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVI YLA VA AT+ K+ A + LE Q+++ANP+LEAFGN+KTV+
Sbjct: 188 KVIMYLAKVACATKKKTDEEEADKK-----------SNLEDQIIEANPVLEAFGNAKTVR 236
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
N+NSSRFGKFIRI+F +G I+GA+IE YLLEKSRV Q ER++HIFYQ+ + E
Sbjct: 237 NNNSSRFGKFIRIHFGPTGKIAGADIETYLLEKSRVTYQQSAERNYHIFYQMCSN-AIPE 295
Query: 907 KSEYLLEGVDN--YRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAV 1080
+E +L D+ Y F+ +T+ ++ DV+E + I+GF +E S+ + +++
Sbjct: 296 LNEIMLLTPDSGLYSFINQGCLTVDSIVDVEELKLCDEAFDILGFTKEEKQSMFKCTASI 355
Query: 1081 LLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQN 1260
L +G ++F Q + +QA +KV L G+ +L KA L+P++KVG E V K Q
Sbjct: 356 LHMGEMKFKQRPREEQAESGGTAEAEKVAFLCGINAGDLLKALLKPKVKVGTEMVTKGQT 415
Query: 1261 QEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQ 1440
Q +V A+AK+ Y+R+F WLV R+NK+LD T + +IG+LDIAGFEIFD NSFEQ
Sbjct: 416 LNQVVNSVGALAKSLYDRMFNWLVKRVNKTLD-TKAKRNYYIGVLDIAGFEIFDYNSFEQ 474
Query: 1441 ICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLD 1620
+C NYTNE+LQQ + MFILEQEEY++EGI W+FIDFG+DLQ IDLIEKPMG+L++L+
Sbjct: 475 LCFNYTNERLQQFLQHHMFILEQEEYKKEGIVWEFIDFGMDLQMCIDLIEKPMGILSILE 534
Query: 1621 EECLFPKANDKSFVEKLQKTH-NKHPKFIVPDMRSK-----SHFAVVHYAGRVDYSADQW 1782
EEC+FPKA+DKS +KL H K+ F P ++ +HF + HYAG V YS W
Sbjct: 535 EECMFPKADDKSLQDKLYSNHMGKNRMFTKPGKPTRPNQRMAHFELHHYAGNVPYSITGW 594
Query: 1783 LMKNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKG---MFRT 1953
L KN DP+NENVV L+ S +P VA ++K A E A G + ++G F+T
Sbjct: 595 LDKNRDPINENVVSLLGASKEPLVAELFK---------AAPEEVAGGGKKKRGKSAAFQT 645
Query: 1954 VSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICR 2133
+S +H+E L KLM L +T PHFVRC+IPN K+ G I++ LVL QL+CNGVLEGIRICR
Sbjct: 646 ISAVHRESLNKLMKNLYSTHPHFVRCLIPNELKQPGLIDAELVLHQLQCNGVLEGIRICR 705
Query: 2134 QGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRT 2313
+GFP+R+ + EF+ RY IL P+ IP F+DGK K++T L +D YR+G +KVFF+
Sbjct: 706 KGFPSRLIYSEFKQRYSILAPNAIPTGFVDGKTVSEKILTGLQMDPAEYRLGTTKVFFKA 765
Query: 2314 GVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNW 2493
GVL +LEE RD +L+ +I FQA RG+L R+ Y N +L LRNW
Sbjct: 766 GVLGNLEEMRDERLSKIISMFQAHIRGYLIRKAYKKLQDQIIGLSAIQRNIRKWLVLRNW 825
Query: 2494 QWWRL-FTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAV 2670
QWW+L TKVKPLL + R +DE++ + ++ K L K + +E E++ ++ ++
Sbjct: 826 QWWKLERTKVKPLLSIARQEDEMKGRLRQMDKVKVDLAKSDRIKKELEEQNVTLLEQKND 885
Query: 2671 IQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMET 2850
+ QLQ ++ + +D +L + + E + ++ +RL ++K +
Sbjct: 886 LFLQLQTIEDSMGDKEDQVEKLIMQKADFEAQLKELEERLLDEEEAAADLGGHKKKMEQD 945
Query: 2851 VRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGL 3030
++ DK + D +
Sbjct: 946 DQNLKKDIGDLENTLQKAEQDKAHKDNQISTLQGEMAQQDEQIGKLNKERKAPEEANKKT 1005
Query: 3031 TTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL 3210
L E++ H K K +LE L+ELE +L RE++ + +E+ KRK+ +L+ +++ +
Sbjct: 1006 GDSLQAEEDKCNHLNKLKAKLEQTLNELEDNLEREKKVRGGVEKAKRKVEQDLKSTQETV 1065
Query: 3211 AEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETER 3390
+ EL + +++ E+ ++ ++E V +Q++++++Q I+EL E++E ER
Sbjct: 1066 EDLERVKRELEENVRRKETEITSLSSKLEDEQNLVGQLQRKIKELQARIEELEEELEAER 1125
Query: 3391 NARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTM 3567
NAR K E R E+ +LE++ G+ LD+ AT Q DL +++ E+ +R +E+
Sbjct: 1126 NARAKVEKQRAELNRELEEL-GERLDEAGGATSAQIDLNKKREAELLKIRRDLEEASLQH 1184
Query: 3568 EGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADI 3747
E +I + K E+ DQ++Q +K +S+ EKQQ +++ E D+ +I + ++
Sbjct: 1185 EAQISALRKKHQDAANEMADQVDQLQKVKSEKEKQQLRSENE--DLQAQIQHVSKNKGCS 1242
Query: 3748 DKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRL 3927
+K K E+ + + A L + L Q R + E L+ E+ EH + + +
Sbjct: 1243 EKVMKQFESQVADFNARLEDGQRSINELQSQKSRLQAENSDLSSQLEDAEHRVSVLSKEK 1302
Query: 3928 ATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAAR 4107
+ TR + N R + + +A+ ++ EE + ++ +++++ A
Sbjct: 1303 SQLGSQLEDARRSLEDETRARSKLQNELRNMHADMDAVGEQLEEEQESKSDVQRQLSKAS 1362
Query: 4108 QGAGEARRKAE-ESVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
+ R K E E N ++LE+ ++K + + ++ +E + + ++K ++QQEL
Sbjct: 1363 NEIQQWRSKFESEGANRTEELEDQKRKLVSKLTESEQNMEAANAKCSALDKAKSRMQQEL 1422
Query: 4279 EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLL 4458
ED S+E++ A+ EK+Q+ F+ AE + V + + +E R + +
Sbjct: 1423 EDLSIEVDRANANANQMEKKQRAFDKTTAEWQAKVNSLQSELENAQKESRGYSAELYRIK 1482
Query: 4459 NEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQME 4638
++ ++ + R ++L E+ D + G++ HEL+KA+R LE E +++ +E
Sbjct: 1483 ASIEEYQDSIGSLRRENKNLADEIHDLTDQLSEGGRSTHELDKARRRLEMEKEELQAALE 1542
Query: 4639 ELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEK 4818
E E L+ E +R ++ +++E D+ I K+ E + RR + + ++ LE E
Sbjct: 1543 EAEGALEQEEAKVMRAQLEIATVRNEIDKRIQEKEEEFDNTRRNHQRALESMQASLEAEA 1602
Query: 4819 RGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKE 4998
+GK+ A+ +KK+E I ELE L+ +NR K E E Q EE ++ ++
Sbjct: 1603 KGKADAMRIKKKLEQDINELEVALDASNRGKAEMEKTVKRYQQQIREMQTSIEEEQRQRD 1662
Query: 4999 DIAALLREADRKFRAVEAEREQLREANEGLMQARK-QXXXXXXXXXXXRAKGGGISS--E 5169
+ A+R+ + E E+LR A E +ARK +SS
Sbjct: 1663 EARESYTMAERRCTLMSGEVEELRSALEQAERARKGSDNELADANDRVNELTSQVSSVQG 1722
Query: 5170 EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQS 5349
+KR+LE I + A ++ +KA ++ +L E+ + + E +++
Sbjct: 1723 QKRKLEGDINAMQTDLDEMHGELKGADERCKKAMADAARLADELRGEQDHSSQVEKGRKN 1782
Query: 5350 LERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEK 5529
LE ++++ ++ E E+ + + + LE++V LE +L+ E + + R+ ++
Sbjct: 1783 LESQVKEFQIRLDEAEASSLKGGKKMIQKLESRVHELEAELDNEQRRHAETQKNMRKADR 1842
Query: 5530 RLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
RL + Q +++++ E+ +EL++K N K + +RQ++EAE+ + K+R Q E ++
Sbjct: 1843 RLKELAFQADEDRKNQERLQELIDKLNAKIKTFKRQVEEAEEIAAINLAKYRKAQHELEE 1902
Score = 177 bits (449), Expect = 3e-42
Identities = 170/934 (18%), Positives = 369/934 (39%), Gaps = 4/934 (0%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L++T+E + +E RE E+ + + E + +L+ E ++ G+LQ
Sbjct: 1052 RKVEQDLKSTQETVEDLERVKRELEENVRRKETEITSLSSKLEDEQ-------NLVGQLQ 1104
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
+ +EL+ + ++ + L R + + +
Sbjct: 1105 RKIKELQARIEELEEELEAERNARAKVEKQRAELNRELEELGERLDEAGGATSAQIDLNK 1164
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLEN 3099
+ ++ +D ++ K K K +L +
Sbjct: 1165 KREAELLKIRRDLEEASLQHEAQISALRKKHQDAANEMADQVDQLQKVK-SEKEKQQLRS 1223
Query: 3100 QLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQH 3279
+ +L+ + + K E+ ++ +++ D L + + EL +Q + E
Sbjct: 1224 ENEDLQAQIQHVSKNKGCSEKVMKQFESQVADFNARLEDGQRSINELQSQKSRLQAENSD 1283
Query: 3280 QLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGD 3459
++ ++ V+++ K+ + + +++ R +E E AR+K + R + A ++ V
Sbjct: 1284 LSSQLEDAEHRVSVLSKEKSQLGSQLEDARRSLEDETRARSKLQNELRNMHADMDAVGEQ 1343
Query: 3460 VLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQ 3639
+ ++ + + +Q +S+ E+ + E ++E+QK K ++ E +E
Sbjct: 1344 LEEEQESKSDVQRQLSKASNEIQQWRSKFESEGANRTEELEDQKRKLVSKLTESEQNMEA 1403
Query: 3640 HKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEH 3819
+ S L+K +++ QE D++ E+ A+ ++KK++ + E QA +
Sbjct: 1404 ANAKCSALDKAKSRMQQELEDLSIEVDRANANANQMEKKQRAFDKTTAEWQAKVNSLQSE 1463
Query: 3820 KRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIAN 3999
+ EL + EE + + +++R R
Sbjct: 1464 LENAQKESRGYSAELYRIKASIEEYQDSIGSLRRENKNLADEIHDLTDQLSEGGRSTHEL 1523
Query: 4000 INRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEEL--- 4170
R+LE EK L EEAEG E ++ A+ R + ++ + ++ EE
Sbjct: 1524 DKARRRLEMEKEELQAALEEAEGALEQEEAKVMRAQLEIATVRNEIDKRIQEKEEEFDNT 1583
Query: 4171 RKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKF 4350
R+ + R +E +Q LE K ++ KKK++Q++ + + L+ + EK K++
Sbjct: 1584 RRNHQRALESMQASLEAEAKGKADAMRIKKKLEQDINELEVALDASNRGKAEMEKTVKRY 1643
Query: 4351 ESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQEL 4530
+ Q+ E + ++++ RD + E R + EV+ ++ LE+++R R+ EL
Sbjct: 1644 QQQIREMQTSIEEEQRQRDEARESYTMAERRCTLMSGEVEELRSALEQAERARKGSDNEL 1703
Query: 4531 QDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALK 4710
D+ ++ V ++ KR LE ++N M+ ++E+ L+ A D R + + + A
Sbjct: 1704 ADANDRVNELTSQVSSVQGQKRKLEGDINAMQTDLDEMHGELKGA-DERCKKAMADAARL 1762
Query: 4711 SESDRAISNKDVEAEEKRRGLLKQIRDLENEL-ENEKRGKSGAVSHRKKIENQIGELEQQ 4887
++ R + + E+ R+ L Q+++ + L E E G +K+E+++ ELE +
Sbjct: 1763 ADELRGEQDHSSQVEKGRKNLESQVKEFQIRLDEAEASSLKGGKKMIQKLESRVHELEAE 1822
Query: 4888 LEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQL 5067
L+ R E +R+ADR+ + + + ++
Sbjct: 1823 LDNEQRRHAETQKN----------------------------MRKADRRLKELAFQADED 1854
Query: 5068 REANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELA 5247
R+ E L + +L AKI + +
Sbjct: 1855 RKNQERLQELID-------------------------KLNAKIKTFKRQVEEAEEIAAIN 1889
Query: 5248 IDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQS 5349
+ K RKAQ +LE+ + QK A+ +S
Sbjct: 1890 LAKYRKAQHELEEAEERADTADSTLQKFRAKSRS 1923
Score = 169 bits (427), Expect = 1e-39
Identities = 185/944 (19%), Positives = 398/944 (41%), Gaps = 49/944 (5%)
Frame = +1
Query: 3061 AKHGVKAKGRLENQLHELEQDLNRERQYKSELEQH-------KRKLLAELEDSKDHLAEK 3219
A+ + KGRL Q+ +++ DL + + K ELE+ K L +L+ +D + +K
Sbjct: 842 ARQEDEMKGRLR-QMDKVKVDLAKSDRIKKELEEQNVTLLEQKNDLFLQLQTIEDSMGDK 900
Query: 3220 MGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNAR 3399
+VE+L Q + +L+ R +E + + M+ L++D+ N
Sbjct: 901 EDQVEKLIMQKADFEAQLKELEERLLDEEEAAADLGGHKKKMEQDDQNLKKDIGDLENTL 960
Query: 3400 NKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKI 3579
KAE + Q+ ++G++ + DE + + EE N Q + +
Sbjct: 961 QKAEQDKAHKDNQISTLQGEMAQQ-DEQIGKLNKERKAPEEANKKTGDSLQAEEDKCNHL 1019
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKR 3759
+ KAK + + EL D +E+ KK R +EK + + +Q+ + + L+ + ++++
Sbjct: 1020 NKLKAKLEQTLNELEDNLEREKKVRGGVEKAKRKVEQDLKSTQETVEDLERVKRELEENV 1079
Query: 3760 KIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAX 3939
+ E + + + L E ++ L+ QL+R EL R+ E EE A R
Sbjct: 1080 RRKETEITSLSSKL----EDEQNLVGQLQRKIKELQA--RIEELEEELEAERNARAKVEK 1133
Query: 3940 XXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGA- 4116
RL A + Q++ L++K EAE L+ + E + + A
Sbjct: 1134 QRAELNRELEELGERLDEAGGATSAQID------LNKKREAELLKIRRDLEEASLQHEAQ 1187
Query: 4117 -GEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSM 4293
R+K +++ N+ ++ V+ LQK E E K++++ E ED
Sbjct: 1188 ISALRKKHQDAANEMADQ--------VDQLQKVKSEKE---------KQQLRSENEDLQA 1230
Query: 4294 ELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDI 4473
++++V + SEK K+FESQ+A+ ++ D EL+ +++R+ + E
Sbjct: 1231 QIQHVSKNKGCSEKVMKQFESQVADFNARLE----DGQRSINELQSQKSRLQA---ENSD 1283
Query: 4474 MKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQM----EE 4641
+ LE+++ L +E S +D +++ + +A+ L+ EL +M M E+
Sbjct: 1284 LSSQLEDAEHRVSVLSKEKSQLGSQLEDARRSLEDETRARSKLQNELRNMHADMDAVGEQ 1343
Query: 4642 LEDNLQIAEDARLRLEVTN---QALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELEN 4812
LE+ + D + +L + Q +S+ + +N+ E E+++R L+ ++ + E +E
Sbjct: 1344 LEEEQESKSDVQRQLSKASNEIQQWRSKFESEGANRTEELEDQKRKLVSKLTESEQNMEA 1403
Query: 4813 EKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQA 4992
S + +++ ++ +L +++ AN + E+Q + +
Sbjct: 1404 ANAKCSALDKAKSRMQQELEDLSIEVDRANANANQMEKKQRAFDKTTAEWQAKVNSLQSE 1463
Query: 4993 KEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSE- 5169
E+ R + ++A E+ +++ L + K ++GG + E
Sbjct: 1464 LENAQKESRGYSAELYRIKASIEEYQDSIGSLRRENKNLADEIHDLTDQLSEGGRSTHEL 1523
Query: 5170 --EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEK 5343
+RRLE + + + E K +AQ+++ + ++ ++ + +K E
Sbjct: 1524 DKARRRLEMEKEELQAALEEAEGALEQEEAKVMRAQLEIATVRNEI--DKRIQEKEEEFD 1581
Query: 5344 QSLERSNRDYKAKITELESGAQSRARAQMAA--LEAKVQYLEDQLNVEGQEKTAANRAAR 5517
+ R ++ LE+ A+ +A A LE + LE L+ + K + +
Sbjct: 1582 NTRRNHQRALESMQASLEAEAKGKADAMRIKKKLEQDINELEVALDASNRGKAEMEKTVK 1641
Query: 5518 RLEKRLNDTTQQFEDEKR----------------------------ANEQAKELLEKSNL 5613
R ++++ + E+E+R A EQA+ + S+
Sbjct: 1642 RYQQQIREMQTSIEEEQRQRDEARESYTMAERRCTLMSGEVEELRSALEQAERARKGSDN 1701
Query: 5614 KNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
+ + +++E ++S + + R ++ + + + +++ EL
Sbjct: 1702 ELADANDRVNELTSQVSSVQGQKRKLEGDINAMQTDLDEMHGEL 1745
Score = 150 bits (378), Expect = 5e-34
Identities = 166/893 (18%), Positives = 372/893 (41%), Gaps = 36/893 (4%)
Frame = +1
Query: 3151 ELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQK 3330
+LE+ K K L + +D + ++ +++++ L K D + + E NVTL++
Sbjct: 829 KLERTKVKPLLSIARQEDEMKGRLRQMDKVKVDLAKSDR------IKKELEEQNVTLLE- 881
Query: 3331 QMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSR 3510
Q D+ + + + M + + K M + + AQL++++ +LD+ + A
Sbjct: 882 QKNDLFLQLQTIEDSMGDKEDQVEKLIMQKADFEAQLKELEERLLDEEEAAA-------- 933
Query: 3511 KDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQ 3690
++ K+ +EQ + KK LE +A+Q
Sbjct: 934 ---DLGGHKKKMEQDDQNL-------------------------KKDIGDLENTLQKAEQ 965
Query: 3691 ERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDH 3870
++A +I+ LQ A D++ + ++ +E + D L+ D+ +H
Sbjct: 966 DKAHKDNQISTLQGEMAQQDEQ-------IGKLNKERKAPEEANKKTGDSLQAEEDKCNH 1018
Query: 3871 LNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRA-RQLEDEKNALLD 4047
LN+++ + E ++ L + +A R++E + + +
Sbjct: 1019 LNKLKAKLEQTLNELEDNLEREKKVR---------------GGVEKAKRKVEQDLKSTQE 1063
Query: 4048 EKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQ--QLEELRKKNLRDVEHLQKQLEE 4221
E+ E ++ LE+ + K E+ N QL+ K+ +E L+++LE
Sbjct: 1064 TVEDLERVKRELEENVRRKETEITSLSSKLEDEQNLVGQLQRKIKELQARIEELEEELEA 1123
Query: 4222 SEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLD 4401
A+ ++ + + ++ +ELE+ L+ + KK E+++ + R +++A L
Sbjct: 1124 ERNARAKVEKQRAELNRELEELGERLDEAGGATSAQIDLNKKREAELLKIRRDLEEASLQ 1183
Query: 4402 RDAMSQELRDRETRVLS-LLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHE 4578
+A LR + + + ++VD +++ +S++ ++ L+ E +D + KN
Sbjct: 1184 HEAQISALRKKHQDAANEMADQVDQLQK--VKSEKEKQQLRSENEDLQAQIQHVSKNKGC 1241
Query: 4579 LEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEE 4758
EK + E+++ D ++E+ + ++ + + RL+ N L S+ + A V ++E
Sbjct: 1242 SEKVMKQFESQVADFNARLEDGQRSINELQSQKSRLQAENSDLSSQLEDAEHRVSVLSKE 1301
Query: 4759 KRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXX 4938
K + L Q+ D LE+E R +S K++N++ + ++
Sbjct: 1302 KSQ-LGSQLEDARRSLEDETRARS-------KLQNELRNMHADMDAVGE----------- 1342
Query: 4939 XXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXX 5118
+ EE +++K D+ L +A + + ++ E +EG + +
Sbjct: 1343 ----------QLEEEQESKSDVQRQLSKASNEIQQWRSKFE-----SEGANRTEEL---- 1383
Query: 5119 XXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQR-KAQVQLEQITT 5295
++KR+L +K+ + + C A+DK + + Q +LE ++
Sbjct: 1384 ---------------EDQKRKLVSKLTESEQNMEAANAKCS-ALDKAKSRMQQELEDLSI 1427
Query: 5296 DLSMERTLNQKTEAEKQSLERSNRDYKAKITELES---GAQSRAR---AQMAALEAKVQY 5457
++ + E ++++ +++ +++AK+ L+S AQ +R A++ ++A ++
Sbjct: 1428 EVDRANANANQMEKKQRAFDKTTAEWQAKVNSLQSELENAQKESRGYSAELYRIKASIEE 1487
Query: 5458 ---------------------LEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRA 5574
L DQL+ G+ ++A RRLE + E+ + A
Sbjct: 1488 YQDSIGSLRRENKNLADEIHDLTDQLSEGGRSTHELDKARRRLEMEKEELQAALEEAEGA 1547
Query: 5575 NEQAKELLEKSNLKNRNLRRQLD----EAEDEMSRERTKHRNVQREADDLLDA 5721
EQ + + ++ L+ +R ++D E E+E R H+ L+A
Sbjct: 1548 LEQEEAKVMRAQLEIATVRNEIDKRIQEKEEEFDNTRRNHQRALESMQASLEA 1600
>gi|31235852|ref|XP_319311.1| ENSANGP00000022605 [Anopheles gambiae]
gi|30174786|gb|EAA43612.1| ENSANGP00000022605 [Anopheles gambiae str.
PEST]
Length = 1938
Score = 1139 bits (2947), Expect = 0.0
Identities = 680/1918 (35%), Positives = 1082/1918 (55%), Gaps = 33/1918 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K CWVP++ EG+++G IK + V V L + +D V + NPPK++K EDMS
Sbjct: 36 KKACWVPEEKEGYVLGEIKATKGELVTVALPGVQTK-DFKKDLVSQVNPPKYEKCEDMSN 94
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LTYLN+ASVLHNL+ RYY+ LIYTYSGLFCVVINPYK+ P+Y+ + ++GK+R+E+PP
Sbjct: 95 LTYLNDASVLHNLRQRYYAKLIYTYSGLFCVVINPYKRYPLYTNRCAKMYRGKRRNEVPP 154
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
H+FA++D AY +ML E+QS+L TGESGAGKTENTKKVI Y A + GA+ K NA +
Sbjct: 155 HLFAVSDGAYVNMLTNHENQSMLITGESGAGKTENTKKVIAYFATI-GASGKKDENAEKK 213
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
G LE Q++Q NP+LEAFGN+KTV+NDNSSRFGKFIRI+F SG ++G
Sbjct: 214 -------------GSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFTGSGKLAG 260
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSE--YLLEGVDNYRFLVNRGIT 969
A+IE YLLEK+RV+ Q ERS+HIFYQI+ G S K E +L + +Y + IT
Sbjct: 261 ADIETYLLEKARVISQQTLERSYHIFYQIMSG-SVKGLKEMCFLSNDIYDYNSVSQGKIT 319
Query: 970 LPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDR 1149
+PNVDD +E T + ++GF +E +I R+ SAV+ +G ++F Q+ + +QA
Sbjct: 320 IPNVDDGEECLLTDEAFNVLGFTQEEKDNIYRITSAVMHMGRMQFKQKGREEQAEADGTE 379
Query: 1150 VIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWL 1329
+V LLG+ +L K L+PRIKVG EFV K QN++Q +V A+ K ++RLFKWL
Sbjct: 380 DGDRVAKLLGVGTDDLYKNLLKPRIKVGNEFVTKGQNKDQVTNSVGALCKGIFDRLFKWL 439
Query: 1330 VTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQ 1509
V + N++LD T ++ A FIG+LDIAGFEIFD N FEQ+CIN+TNEKLQQ FN+ MF+LEQ
Sbjct: 440 VKKCNETLD-TKQKRAQFIGVLDIAGFEIFDFNGFEQLCINFTNEKLQQFFNHHMFVLEQ 498
Query: 1510 EEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-N 1686
EEY++EGI W FIDFG+DL IDLIEKPMG+L++L+EE +FPKA D++F EKL H
Sbjct: 499 EEYKKEGINWAFIDFGMDLLACIDLIEKPMGILSILEEESMFPKATDQTFAEKLMTNHLG 558
Query: 1687 KHPKFIVPDMRS----KSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFV 1854
K F+ P HFA+ HYAG V Y+ WL KN DPLN+ VV + ++ +
Sbjct: 559 KSAPFMKPRPPKPGIPAGHFAIGHYAGVVSYNITGWLEKNKDPLNDTVVDQFKKGSNALM 618
Query: 1855 AGIWKD--AEFAGICAAEMNETAFGMRSRKGM-FRTVSQLHKEQLTKLMTTLRNTSPHFV 2025
I+ D + A AA+ G R +KG F TVS +KEQL LMTTL++T PHFV
Sbjct: 619 VEIFADHPGQSADPAAAK------GGRGKKGAGFATVSSSYKEQLNNLMTTLKSTQPHFV 672
Query: 2026 RCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVI 2205
RCIIPN K +G ++++LV+ QL CNGVLEGIRICR+GFPNR+ + +F+ RY IL P +
Sbjct: 673 RCIIPNEMKTAGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKLRYLILAPAAM 732
Query: 2206 PKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQ 2385
+GK++ K A+ +D + YRIG +KVFFR GVL +EE RD +L+ ++ QA
Sbjct: 733 QAE-TEGKKAAEKCFEAIGLDPDSYRIGHTKVFFRAGVLGQMEEFRDERLSKIMSWMQAW 791
Query: 2386 CRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRA 2565
CRG+LSR+ + N YLKLR W WW+L+ KVKPLL V+R +D+I
Sbjct: 792 CRGYLSRKEFKKMQEQRVSLEIVQRNLRKYLKLRTWAWWKLWQKVKPLLNVSRVEDQIAK 851
Query: 2566 KDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTR 2745
+++ +E K E +E E +++ E+ + + L E E + +L +
Sbjct: 852 LEEKATKAQEAYEKEEKLRKELEALNSKLLAEKTALLDSLSGEKGALQEYQEKAAKLTAQ 911
Query: 2746 NQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNV 2925
+LE + D ++RL+ ++K + + DK +
Sbjct: 912 KNDLENQLRDTQERLAQEEDARNQLFQTKKKLEQEIGSQKKDAEDLELQIQKIEQDKASK 971
Query: 2926 DQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQL 3105
D + + +L E++ H K K +LE L
Sbjct: 972 DHQIRNLNDEIAHQDELINKLNKEKKMQGEVNQKTAEELQAAEDKVNHLNKVKAKLEQTL 1031
Query: 3106 HELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQL 3285
ELE L RE++ + ++E+ KRK+ +L+ +++ +A+ +EL ++++D+E+
Sbjct: 1032 DELEDSLEREKKLRGDVEKAKRKVEGDLKLTQEAVADLERNKKELEQTVLRKDKEISALS 1091
Query: 3286 TRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVL 3465
+ ++E + V +QKQ++++Q I+EL E++E ER AR KAE R ++ +LE++ G+ L
Sbjct: 1092 AKLEDEQSLVGKLQKQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEEL-GERL 1150
Query: 3466 DKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQH 3642
++ AT Q +L +++ E+ +R +E+ EG + + K + V E+ +Q++
Sbjct: 1151 EEAGGATSAQIELNKKREAELAKLRRDLEEANIQHEGTLANLRKKHNDAVAEMAEQVD-- 1208
Query: 3643 KKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAE----S 3810
QL K + +A+ +RA+M E+ + + + +++ E ++Q L E
Sbjct: 1209 -----QLNKLKTKAEHDRANMYNELNNTRTACDQLSREKAAQEKIAKQLQHTLNEVQSKL 1263
Query: 3811 DEHKRTLIDQLERSRDEL----DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXX 3978
DE RTL D + S+ +L L R E+ E + + + +
Sbjct: 1264 DETNRTLND-FDASKKKLSIENSDLLRQLEDAESQVSQLSKIKISLTQQLEDTKRLADEE 1322
Query: 3979 TRLKIANINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHAARQGAGEARRKAEE---S 4146
R + + + R LE + + L ++ +EEAEG + +++++ A A R K E +
Sbjct: 1323 ARERATLLGKFRNLEHDLDNLREQVEEEAEG-KGDIQRQLSKANAEAQLWRSKYESEGVA 1381
Query: 4147 VNQQLEELRKK---NLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRAS 4317
++LEE ++K L + E + L + +A E+ +K+++ E+ED +E++ +
Sbjct: 1382 RAEELEEAKRKLQARLAEAEETIESLNQKCIALEK---TKQRLATEVEDLQLEVDRASSI 1438
Query: 4318 HRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEES 4497
+EK+QK F+ + E ++ V + DA +E R+ T + L + +E LE
Sbjct: 1439 ANAAEKKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAV 1498
Query: 4498 DRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDAR 4677
R ++L E++D + + G+N+HE+EK+++ LEAE ++++ +EE E L+ E+
Sbjct: 1499 RRENKNLADEVKDLLDQIGEGGRNIHEIEKSRKRLEAEKDELQAALEEAEAALEQEENKV 1558
Query: 4678 LRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKI 4857
LR ++ ++ E DR I K+ E E R+ + + ++ LE E +GK+ A+ +KK+
Sbjct: 1559 LRAQLELSQVRQEIDRRIQEKEEEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKL 1618
Query: 4858 ENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKF 5037
E I ELE L+ AN+ E + Q EE ++A++D L ++R+
Sbjct: 1619 EADINELEIALDHANKANAEAQKNIKRYQQQLKDVQSALEEEQRARDDAREQLGISERRA 1678
Query: 5038 RAVEAEREQ----LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQX 5205
A++ E E+ L +A+ G QA ++ A+ I++ KR+LE+++
Sbjct: 1679 NALQNELEESRTLLEQADRGRRQAEQELSDAHEQLNEVSAQNASIAA-AKRKLESELQTL 1737
Query: 5206 XXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKI 5385
+ + + +K +KA V ++ +L E+ Q E +++LE+ ++ + ++
Sbjct: 1738 HSDLDELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRL 1797
Query: 5386 TELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDE 5565
E ES A + + LE +V+ LE +L+ E + A + R+ E+R+ + T Q E++
Sbjct: 1798 DEAESNALKGGKKAIQKLEQRVRELESELDSEQRRHADAQKNLRKSERRIKELTFQSEED 1857
Query: 5566 KRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQR---EADDLLDANEQ 5730
++ +E+ ++L++K K + +RQ++EAE+ + K R Q+ EA++ D EQ
Sbjct: 1858 RKNHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADIAEQ 1915
Score = 157 bits (396), Expect = 4e-36
Identities = 202/966 (20%), Positives = 405/966 (41%), Gaps = 78/966 (8%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMK--- 3258
+LE + + ++ +E + + ELE KLLAE D L+ + G ++E + K
Sbjct: 851 KLEEKATKAQEAYEKEEKLRKELEALNSKLLAEKTALLDSLSGEKGALQEYQEKAAKLTA 910
Query: 3259 RDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQ 3438
+ +L++QL E A Q D + + + ++ +E E ++ K ++ Q
Sbjct: 911 QKNDLENQLRDTQERLA-------QEEDARNQLFQTKKKLEQEIGSQKK---DAEDLELQ 960
Query: 3439 LEKVKGDVLDKVDEATMLQDLMSRKDEEVN-----------ATKRAIEQIQHTME--GKI 3579
++K++ D K + L D ++ +DE +N ++ E++Q + +
Sbjct: 961 IQKIEQDKASKDHQIRNLNDEIAHQDELINKLNKEKKMQGEVNQKTAEELQAAEDKVNHL 1020
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKR 3759
+ KAK + ++EL D +E+ KK R +EK + + + + + L Q + AD+++ +
Sbjct: 1021 NKVKAKLEQTLDELEDSLEREKKLRGDVEKAKRKVEGD-------LKLTQEAVADLERNK 1073
Query: 3760 KIHEAHLM----EIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRL 3927
K E ++ EI A L+ E +++L+ +L++ EL R+ E EE A Q R
Sbjct: 1074 KELEQTVLRKDKEISA-LSAKLEDEQSLVGKLQKQIKELQA--RIEELEEEVEAERQARA 1130
Query: 3928 ATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAE--GLRAHLEKEIHA 4101
RL+ A + Q+E L++K EAE LR LE E +
Sbjct: 1131 KAEKQRADLARELEELGERLEEAGGATSAQIE------LNKKREAELAKLRRDLE-EANI 1183
Query: 4102 ARQGA-GEARRKAEESVNQ------QLEELRKKNLRDVEHLQKQLEESEVAKERILQSK- 4257
+G R+K ++V + QL +L+ K D ++ +L + A +++ + K
Sbjct: 1184 QHEGTLANLRKKHNDAVAEMAEQVDQLNKLKTKAEHDRANMYNELNNTRTACDQLSREKA 1243
Query: 4258 ------KKIQQELEDSSMELENVRASHRDSEKRQKKFE-----------------SQMAE 4368
K++Q L + +L+ + D + +KK SQ+++
Sbjct: 1244 AQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSIENSDLLRQLEDAESQVSQLSK 1303
Query: 4369 ERVAVQKALLDRDAMS-QELRDRET---RVLSLLNEVDIMKEHLEESDRVRRSLQQELQD 4536
++++ + L D ++ +E R+R T + +L +++D ++E +EE + +Q++L
Sbjct: 1304 IKISLTQQLEDTKRLADEEARERATLLGKFRNLEHDLDNLREQVEEEAEGKGDIQRQLSK 1363
Query: 4537 SISN--------KDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEV 4692
+ + + + ELE+AKR L+A L + +E L E + RL
Sbjct: 1364 ANAEAQLWRSKYESEGVARAEELEEAKRKLQARLAEAEETIESLNQKCIALEKTKQRLAT 1423
Query: 4693 TNQALKSESDRAISNKDVEAEEKRRGLLK-------QIRDLENELENEKRGKSGAVSHRK 4851
+ L+ E DRA S + AE+K++ K ++ DL EL+ ++ +
Sbjct: 1424 EVEDLQLEVDRASSIANA-AEKKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELF 1482
Query: 4852 KIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADR 5031
+++ E ++QLE R E + +D+ + E R
Sbjct: 1483 RLKGAYEEGQEQLEAVRR---------------------ENKNLADEVKDLLDQIGEGGR 1521
Query: 5032 KFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXX 5211
+E R++L + L A ++ + S+ ++ ++ +I +
Sbjct: 1522 NIHEIEKSRKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEIDRRIQEKEE 1581
Query: 5212 XXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITE 5391
+ N + A+D SM+ +L + + + ++L R + +A I E
Sbjct: 1582 EFENTRKNHQRALD----------------SMQASLEAEAKGKAEAL-RMKKKLEADINE 1624
Query: 5392 LESGAQSRARAQMAA---LEAKVQYLEDQLNVEGQEKTAANRAARRL---EKRLNDTTQQ 5553
LE +A A ++ Q L+D + +E+ A + A +L E+R N +
Sbjct: 1625 LEIALDHANKANAEAQKNIKRYQQQLKDVQSALEEEQRARDDAREQLGISERRANALQNE 1684
Query: 5554 FEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQL 5733
E+ + EQA ++ + + QL+E + + R ++ E L ++L
Sbjct: 1685 LEESRTLLEQADRGRRQAEQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDEL 1744
Query: 5734 TRELMN 5751
E N
Sbjct: 1745 LNEAKN 1750
Score = 109 bits (272), Expect = 9e-22
Identities = 138/637 (21%), Positives = 266/637 (41%), Gaps = 88/637 (13%)
Frame = +1
Query: 3028 LTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDH 3207
L QL D E + K K L QL + ++ + E + ++ L R L +L++ ++
Sbjct: 1287 LLRQLEDAESQVSQLSKIKISLTQQLEDTKRLADEEARERATLLGKFRNLEHDLDNLREQ 1346
Query: 3208 LAEKMGKVEELNNQLMKRDEELQHQLTRYDEES-ANVTLMQKQMRDMQTTIDELREDMET 3384
+ E+ ++ QL K + E Q ++Y+ E A +++ R +Q + E E +E+
Sbjct: 1347 VEEEAEGKGDIQRQLSKANAEAQLWRSKYESEGVARAEELEEAKRKLQARLAEAEETIES 1406
Query: 3385 ERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRK----DEEVNATKRAIEQ 3552
E T++ + ++E D+ +VD A+ + + +K D+ + K ++
Sbjct: 1407 LNQKCIALEKTKQRLATEVE----DLQLEVDRASSIANAAEKKQKAFDKIIGEWKLKVDD 1462
Query: 3553 IQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQA 3732
+ ++ +E + +S ++ L E+ ++Q + ++ E D+ +I
Sbjct: 1463 LAAELDASQKECR-NYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGR 1521
Query: 3733 SRADIDKKRKIHEAHLMEIQANLAESD-----EHKRTLIDQLERS--RDELDHLNRVREE 3891
+ +I+K RK EA E+QA L E++ E + L QLE S R E+D + +EE
Sbjct: 1522 NIHEIEKSRKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEIDRRIQEKEE 1581
Query: 3892 E-EHAFANMQRRLATAXXXXXXXXXXXXXXTRLKI---ANINRARQLEDEKNALLDE--- 4050
E E+ N QR L + R+K A+IN D N E
Sbjct: 1582 EFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQK 1641
Query: 4051 -----KEEAEGLRAHLEKEIHA---ARQGAGEARRKAEESVNQ---------QLEELRKK 4179
+++ + +++ LE+E A AR+ G + R+A N+ Q + R++
Sbjct: 1642 NIKRYQQQLKDVQSALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRRQ 1701
Query: 4180 NLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKF--- 4350
+++ +QL E I +K+K++ EL+ +L+ + ++SE++ KK
Sbjct: 1702 AEQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDELLNEAKNSEEKAKKAMVD 1761
Query: 4351 ------ESQMAEERVAVQKALLDRDAMSQELRDR----------------------ETRV 4446
E + ++ Q+ L R A+ Q++++ E RV
Sbjct: 1762 AARLADELRAEQDHAQTQEKL--RKALEQQIKELQVRLDEAESNALKGGKKAIQKLEQRV 1819
Query: 4447 LSLLNEVDI-MKEHLE-------------------ESDRVRRSLQQELQDSISNK-DDFG 4563
L +E+D + H + E DR Q+L D + K +
Sbjct: 1820 RELESELDSEQRRHADAQKNLRKSERRIKELTFQSEEDRKNHERMQDLVDKLQQKIKTYK 1879
Query: 4564 KNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDA 4674
+ + E E+ A+ + ++EE E+ IAE A
Sbjct: 1880 RQIEEAEEIAALNLAKFRKAQQELEEAEERADIAEQA 1916
Score = 89.4 bits (220), Expect = 1e-15
Identities = 105/527 (19%), Positives = 229/527 (42%), Gaps = 6/527 (1%)
Frame = +1
Query: 4180 NLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQ 4359
N+ VE +LEE + + ++K+++ELE + +L + + DS +K
Sbjct: 841 NVSRVEDQIAKLEEKATKAQEAYEKEEKLRKELEALNSKLLAEKTALLDSLSGEK---GA 897
Query: 4360 MAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDS 4539
+ E + K ++ + +LRD + R L E D + + ++ L+QE+
Sbjct: 898 LQEYQEKAAKLTAQKNDLENQLRDTQER---LAQEEDARNQLFQ----TKKKLEQEIGSQ 950
Query: 4540 ISNKDDFGKNVHELEKAKRSLEAE---LNDMRVQMEELEDNLQIAEDARLRLEVTNQALK 4710
+ +D + ++E+ K S + + LND +EL + L ++ +++ EV +
Sbjct: 951 KKDAEDLELQIQKIEQDKASKDHQIRNLNDEIAHQDELINKLN--KEKKMQGEVNQKT-- 1006
Query: 4711 SESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
+E +A +K + + L + + +LE+ LE EK+ + ++K+E + ++ +
Sbjct: 1007 AEELQAAEDKVNHLNKVKAKLEQTLDELEDSLEREKKLRGDVEKAKRKVEGDLKLTQEAV 1066
Query: 4891 EVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLR 5070
R K+E + +I A+ ED +L+ + ++ + ++A E+L
Sbjct: 1067 ADLERNKKELEQTVLRK-----DKEISALSAKL--EDEQSLVGKLQKQIKELQARIEELE 1119
Query: 5071 EANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAI 5250
E E QAR AK ++ R LE + + EL
Sbjct: 1120 EEVEAERQAR--------------AKAEKQRADLARELEELGERLEEAGGATSAQIEL-- 1163
Query: 5251 DKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELE---SGAQSRAR 5421
+K + +L ++ DL ++ T A +L + + D A++ E + +++A
Sbjct: 1164 --NKKREAELAKLRRDLEEANIQHEGTLA---NLRKKHNDAVAEMAEQVDQLNKLKTKAE 1218
Query: 5422 AQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLE 5601
A + ++ + +EK A + A++L+ LN+ + ++ R +
Sbjct: 1219 HDRANMYNELNNTRTACDQLSREKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKK 1278
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
K +++N +L RQL++AE ++S+ ++ ++ +D ++ RE
Sbjct: 1279 KLSIENSDLLRQLEDAESQVSQLSKIKISLTQQLEDTKRLADEEARE 1325
Score = 79.7 bits (195), Expect = 8e-13
Identities = 81/418 (19%), Positives = 183/418 (43%), Gaps = 25/418 (5%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L +Q+ E ++++ + + LE K +L A LE+++ L ++ KV +L + +E
Sbjct: 1512 LLDQIGEGGRNIHEIEKSRKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQE 1571
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ ++ +EE N ++ Q +D ++ +E E + +A ++++ A + ++
Sbjct: 1572 IDRRIQEKEEEFENTR------KNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINEL 1625
Query: 3451 KGDVLDKVDEATM-LQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+ LD ++A Q + R +++ + A+E+ Q + EQ R+ L +
Sbjct: 1626 E-IALDHANKANAEAQKNIKRYQQQLKDVQSALEEEQRARDDA-REQLGISERRANALQN 1683
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL-- 3801
++E+ + Q ++ + QA+QE +D +++ + A A I ++ E+ L + ++L
Sbjct: 1684 ELEESRTLLEQADRGRRQAEQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDE 1743
Query: 3802 ----AESDEHKRT--------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
A++ E K L D+L +D ++R+ E +Q RL A
Sbjct: 1744 LLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAESN 1803
Query: 3946 XXXXXXXXXXXTRLKIANIN------RARQLEDEKNALLDEKEEAE-GLRAHLEKEIHAA 4104
++ + + R + +KN E+ E ++ +++ H
Sbjct: 1804 ALKGGKKAIQKLEQRVRELESELDSEQRRHADAQKNLRKSERRIKELTFQSEEDRKNHER 1863
Query: 4105 RQGAGEARRKAEESVNQQLEELRK---KNLRDVEHLQKQLEESEVAKERILQSKKKIQ 4269
Q + ++ ++ +Q+EE + NL Q++LEE+E + Q+ K +
Sbjct: 1864 MQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADIAEQAATKFR 1921
Score = 53.9 bits (128), Expect = 5e-05
Identities = 62/408 (15%), Positives = 157/408 (38%), Gaps = 12/408 (2%)
Frame = +1
Query: 2533 QVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAE 2712
++ ++ + A+ DEL+A E + E + E K+ + +E + +++++ + + E
Sbjct: 1525 EIEKSRKRLEAEKDELQAALE---EAEAALEQEENKVLRAQLELSQVRQEIDRRIQEKEE 1581
Query: 2713 LDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXX 2892
+ + + ++ M+ L ++K + +
Sbjct: 1582 ------EFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKA 1635
Query: 2893 XXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHG 3072
+ Q Q A D L +L + +
Sbjct: 1636 NAEAQKNIKRYQQQLKDVQSALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQA 1695
Query: 3073 VKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQL 3252
+ + + E +L + + LN + + KRKL +EL+ L E + + + +
Sbjct: 1696 DRGRRQAEQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDELLNEAKNSEEKA 1755
Query: 3253 MKR-------DEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELRED-METERNARNKA 3408
K +EL+ + + +++Q++++Q +DE + ++ + A K
Sbjct: 1756 KKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAESNALKGGKKAIQKL 1815
Query: 3409 EMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQ 3588
E RE+ ++L+ + D + + + ++ E++Q ++ K++++
Sbjct: 1816 EQRVRELESELDSEQRRHADAQKNLRKSERRIKELTFQSEEDRKNHERMQDLVD-KLQQK 1874
Query: 3589 KAKFSRQVEELHD----QIEQHKKQRSQLEKQQNQADQERADMAQEIA 3720
+ RQ+EE + + + +K + +LE+ + ERAD+A++ A
Sbjct: 1875 IKTYKRQIEEAEEIAALNLAKFRKAQQELEEAE-----ERADIAEQAA 1917
>gi|31235842|ref|XP_319309.1| ENSANGP00000024129 [Anopheles gambiae]
gi|30174787|gb|EAA43613.1| ENSANGP00000024129 [Anopheles gambiae str.
PEST]
Length = 1937
Score = 1139 bits (2946), Expect = 0.0
Identities = 674/1913 (35%), Positives = 1083/1913 (56%), Gaps = 28/1913 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K CWVP++ EG+++G IK T E++ + + ++ + + NPPKF+K+EDM++
Sbjct: 36 KKACWVPEEKEGYVLGEIKA-TKGELVTVALPGGEEKNFKKEQLSQVNPPKFEKVEDMAD 94
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LTYLNEA+VLHNL+ RYYS LIYTYSGLFCVVINPYK+ P+Y+ + ++GK+R+E+PP
Sbjct: 95 LTYLNEAAVLHNLRQRYYSKLIYTYSGLFCVVINPYKRYPLYTNRCAKMYRGKRRNEVPP 154
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
H+FA++D AY +ML E+QS+L TGESGAGKTENTKKVI Y A + GA+ K NA +
Sbjct: 155 HLFAVSDGAYVNMLTNHENQSMLITGESGAGKTENTKKVIAYFATI-GASGKKDENAEKK 213
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
G LE Q++Q NP+LEAFGN+KTV+NDNSSRFGKFIRI+F SG ++G
Sbjct: 214 -------------GSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFTGSGKLAG 260
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLL-EGVDNYRFLVNRGITL 972
A+IE YLLEK+RV+ Q ERS+HIFYQI+ G K + LL + +Y + T+
Sbjct: 261 ADIETYLLEKARVISQQTLERSYHIFYQIMSGSVKGLKEKCLLSNNIHDYHIVAQGKTTI 320
Query: 973 PNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRV 1152
P+VDD +E T + ++GF +E +I R+ SAV+ +G ++F Q+ + +QA
Sbjct: 321 PSVDDGEEMQITDEAFNVLGFTQEEKDNIYRITSAVMHMGRMQFKQKGREEQAEADGTED 380
Query: 1153 IQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLV 1332
+V LLG+ +L K L+PRIKVG EFV K QN++Q +V A+ K ++RLFKWLV
Sbjct: 381 GDRVAKLLGVGTDDLYKNLLKPRIKVGNEFVTKGQNKDQVTNSVGALCKGIFDRLFKWLV 440
Query: 1333 TRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQE 1512
+ N++LD T ++ A FIG+LDIAGFEIFD N FEQ+CIN+TNEKLQQ FN+ MF+LEQE
Sbjct: 441 KKCNETLD-TKQKRAQFIGVLDIAGFEIFDFNGFEQLCINFTNEKLQQFFNHHMFVLEQE 499
Query: 1513 EYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NK 1689
EY++EGI W FIDFG+DL IDLIEKPMG+L++L+EE +FPKA D++F EKL H K
Sbjct: 500 EYKKEGINWAFIDFGMDLLACIDLIEKPMGILSILEEESMFPKATDQTFAEKLMTNHLGK 559
Query: 1690 HPKFIVPDMRS----KSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVA 1857
F+ P HFA+ HYAG V Y+ WL KN DPLN+ VV + ++ +
Sbjct: 560 SAPFMKPRPPKPGIPAGHFAIGHYAGVVSYNITGWLEKNKDPLNDTVVDQFKKGSNALMV 619
Query: 1858 GIWKD--AEFAGICAAEMNETAFGMRSRKGM-FRTVSQLHKEQLTKLMTTLRNTSPHFVR 2028
I+ D + A AA+ G R +KG F TVS +KEQL LMTTL++T PHFVR
Sbjct: 620 EIFADHPGQSADPAAAK------GGRGKKGAGFATVSSSYKEQLNNLMTTLKSTQPHFVR 673
Query: 2029 CIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIP 2208
CIIPN K +G ++++LV+ QL CNGVLEGIRICR+GFPNR+ + +F+ RY+IL P +I
Sbjct: 674 CIIPNEMKTAGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKLRYKILCPQLI- 732
Query: 2209 KNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQC 2388
K ++ + ++T + + +R+G++KVFFR GVL +EE RD +L+ ++ QA C
Sbjct: 733 KEPCSPEKVTQIVLTHIQLPEEQFRMGKTKVFFRAGVLGQMEEFRDERLSKIMSWMQAWC 792
Query: 2389 RGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAK 2568
RG+LSR+ + N YLKLR W WW+L+ KVKPLL V+R +D+I
Sbjct: 793 RGYLSRKEFKKMQEQRVSLEIVQRNLRKYLKLRTWAWWKLWQKVKPLLNVSRVEDQIAKL 852
Query: 2569 DDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRN 2748
+++ +E K E +E E +++ E+ + + L E E + +L +
Sbjct: 853 EEKATKAQEAYEKEEKLRKELEALNSKLLAEKTALLDSLSGEKGALQEYQEKAAKLTAQK 912
Query: 2749 QELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVD 2928
+LE + D ++RL+ ++K + + DK + D
Sbjct: 913 NDLENQLRDTQERLAQEEDARNQLFQTKKKLEQEIGSQKKDAEDLELQIQKIEQDKASKD 972
Query: 2929 QXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLH 3108
+ + +L E++ H K K +LE L
Sbjct: 973 HQIRNLNDEIAHQDELINKLNKEKKMQGEVNQKTAEELQAAEDKVNHLNKVKAKLEQTLD 1032
Query: 3109 ELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLT 3288
ELE L RE++ + ++E+ KRK+ +L+ +++ +A+ +EL ++++D+E+
Sbjct: 1033 ELEDSLEREKKLRGDVEKAKRKVEGDLKLTQEAVADLERNKKELEQTVLRKDKEISALSA 1092
Query: 3289 RYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLD 3468
+ ++E + V +QKQ++++Q I+EL E++E ER AR KAE R ++ +LE++ G+ L+
Sbjct: 1093 KLEDEQSLVGKLQKQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEEL-GERLE 1151
Query: 3469 KVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHK 3645
+ AT Q +L +++ E+ +R +E+ EG + + K + V E+ +Q++Q
Sbjct: 1152 EAGGATSAQIELNKKREAELAKLRRDLEEANIQHEGTLANLRKKHNDAVAEMAEQVDQLN 1211
Query: 3646 KQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKR 3825
K +++ EK++ Q E D L +A +K K + L E+Q+ L DE R
Sbjct: 1212 KLKTKAEKERTQYFAELNDARIGCDQLSNEKAAQEKIAKQLQHTLNEVQSKL---DETNR 1268
Query: 3826 TLIDQLERSRDEL----DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKI 3993
TL D + S+ +L L R E+ E + + + + R +
Sbjct: 1269 TLND-FDASKKKLSIENSDLLRQLEDAESQVSQLSKIKISLTQQLEDTKRLADEEARERA 1327
Query: 3994 ANINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHAARQGAGEARRKAEE---SVNQQL 4161
+ + R LE + + L ++ +EEAEG + +++++ A A R K E + ++L
Sbjct: 1328 TLLGKFRNLEHDLDNLREQVEEEAEG-KGDIQRQLSKANAEAQLWRSKYESEGVARAEEL 1386
Query: 4162 EELRKK---NLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSE 4332
EE ++K L + E + L + +A E+ +K+++ E+ED +E++ + +E
Sbjct: 1387 EEAKRKLQARLAEAEETIESLNQKCIALEK---TKQRLATEVEDLQLEVDRASSIANAAE 1443
Query: 4333 KRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRR 4512
K+QK F+ + E ++ V + DA +E R+ T + L + +E LE R +
Sbjct: 1444 KKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENK 1503
Query: 4513 SLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEV 4692
+L E++D + + G+N+HE+EK+++ LEAE ++++ +EE E L+ E+ LR ++
Sbjct: 1504 NLADEVKDLLDQIGEGGRNIHEIEKSRKRLEAEKDELQAALEEAEAALEQEENKVLRAQL 1563
Query: 4693 TNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIG 4872
++ E DR I K+ E E R+ + + ++ LE E +GK+ A+ +KK+E I
Sbjct: 1564 ELSQVRQEIDRRIQEKEEEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADIN 1623
Query: 4873 ELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEA 5052
ELE L+ AN+ E + Q EE ++A++D L ++R+ A++
Sbjct: 1624 ELEIALDHANKANAEAQKNIKRYQQQLKDVQSALEEEQRARDDAREQLGISERRANALQN 1683
Query: 5053 EREQ----LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXX 5220
E E+ L +A+ G QA ++ A+ I++ KR+LE+++
Sbjct: 1684 ELEESRTLLEQADRGRRQAEQELSDAHEQLNEVSAQNASIAA-AKRKLESELQTLHSDLD 1742
Query: 5221 XXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES 5400
+ + + +K +KA V ++ +L E+ Q E +++LE+ ++ + ++ E ES
Sbjct: 1743 ELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAES 1802
Query: 5401 GAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANE 5580
A + + LE +V+ LE +L+ E + A + R+ E+R+ + T Q E++++ +E
Sbjct: 1803 NALKGGKKAIQKLEQRVRELESELDSEQRRHADAQKNLRKSERRIKELTFQSEEDRKNHE 1862
Query: 5581 QAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQR---EADDLLDANEQ 5730
+ ++L++K K + +RQ++EAE+ + K R Q+ EA++ D EQ
Sbjct: 1863 RMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADIAEQ 1915
Score = 155 bits (391), Expect = 1e-35
Identities = 186/948 (19%), Positives = 398/948 (41%), Gaps = 60/948 (6%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMK--- 3258
+LE + + ++ +E + + ELE KLLAE D L+ + G ++E + K
Sbjct: 851 KLEEKATKAQEAYEKEEKLRKELEALNSKLLAEKTALLDSLSGEKGALQEYQEKAAKLTA 910
Query: 3259 RDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQ 3438
+ +L++QL E A Q D + + + ++ +E E ++ K ++ Q
Sbjct: 911 QKNDLENQLRDTQERLA-------QEEDARNQLFQTKKKLEQEIGSQKK---DAEDLELQ 960
Query: 3439 LEKVKGDVLDKVDEATMLQDLMSRKDEEVN-----------ATKRAIEQIQHTME--GKI 3579
++K++ D K + L D ++ +DE +N ++ E++Q + +
Sbjct: 961 IQKIEQDKASKDHQIRNLNDEIAHQDELINKLNKEKKMQGEVNQKTAEELQAAEDKVNHL 1020
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKR 3759
+ KAK + ++EL D +E+ KK R +EK + + + + + L Q + AD+++ +
Sbjct: 1021 NKVKAKLEQTLDELEDSLEREKKLRGDVEKAKRKVEGD-------LKLTQEAVADLERNK 1073
Query: 3760 KIHEAHLM----EIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRL 3927
K E ++ EI A L+ E +++L+ +L++ EL R+ E EE A Q R
Sbjct: 1074 KELEQTVLRKDKEISA-LSAKLEDEQSLVGKLQKQIKELQA--RIEELEEEVEAERQAR- 1129
Query: 3928 ATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAAR 4107
+ + + AR+LE+ L E+ E G + E++ R
Sbjct: 1130 -----------------AKAEKQRADLARELEE-----LGERLEEAGGATSAQIELNKKR 1167
Query: 4108 QGAGEARRKAEESVNQQ----LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQE 4275
+ R+ E N Q L LRKK+ V + +Q+++ K + + + + E
Sbjct: 1168 EAELAKLRRDLEEANIQHEGTLANLRKKHNDAVAEMAEQVDQLNKLKTKAEKERTQYFAE 1227
Query: 4276 LEDSSM---ELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRV 4446
L D+ + +L N +A+ K+ + +++ + + L D DA ++L +
Sbjct: 1228 LNDARIGCDQLSNEKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSIENS-- 1285
Query: 4447 LSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMR 4626
LL +++ + + + +++ SL Q+L+D+ D+ + L R+LE +L+++R
Sbjct: 1286 -DLLRQLEDAESQVSQLSKIKISLTQQLEDTKRLADEEARERATLLGKFRNLEHDLDNLR 1344
Query: 4627 VQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENEL 4806
Q+EE + + + Q +S+ + + E EE +R L ++ + E +
Sbjct: 1345 EQVEEEAEGKGDIQRQLSKANAEAQLWRSKYESEGVARAEELEEAKRKLQARLAEAEETI 1404
Query: 4807 ENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEAR 4986
E+ + ++++ ++ +L+ +++ A+ + E++++ ++
Sbjct: 1405 ESLNQKCIALEKTKQRLATEVEDLQLEVDRASSIANAAEKKQKAFDKIIGEWKLKVDDLA 1464
Query: 4987 QAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISS 5166
+ R + ++ E+ +E E + + K +GG
Sbjct: 1465 AELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGRNIH 1524
Query: 5167 E---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEA 5337
E ++RLEA+ + ++ E +K +AQ++L Q+ ++ +R + +K E
Sbjct: 1525 EIEKSRKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEI--DRRIQEKEEE 1582
Query: 5338 EKQSLERSNRDYKAKITELESGAQSRARA--QMAALEAKVQYLEDQLNVEGQEKTAANRA 5511
+ + + R + LE+ A+ +A A LEA + LE L+ + A +
Sbjct: 1583 FENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQKN 1642
Query: 5512 ARRLEKRLNDTTQQFEDEKR----------------------------ANEQAKELLEKS 5607
+R +++L D E+E+R EQA ++
Sbjct: 1643 IKRYQQQLKDVQSALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRRQA 1702
Query: 5608 NLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
+ + QL+E + + R ++ E L ++L E N
Sbjct: 1703 EQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDELLNEAKN 1750
Score = 109 bits (272), Expect = 9e-22
Identities = 138/637 (21%), Positives = 266/637 (41%), Gaps = 88/637 (13%)
Frame = +1
Query: 3028 LTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDH 3207
L QL D E + K K L QL + ++ + E + ++ L R L +L++ ++
Sbjct: 1287 LLRQLEDAESQVSQLSKIKISLTQQLEDTKRLADEEARERATLLGKFRNLEHDLDNLREQ 1346
Query: 3208 LAEKMGKVEELNNQLMKRDEELQHQLTRYDEES-ANVTLMQKQMRDMQTTIDELREDMET 3384
+ E+ ++ QL K + E Q ++Y+ E A +++ R +Q + E E +E+
Sbjct: 1347 VEEEAEGKGDIQRQLSKANAEAQLWRSKYESEGVARAEELEEAKRKLQARLAEAEETIES 1406
Query: 3385 ERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRK----DEEVNATKRAIEQ 3552
E T++ + ++E D+ +VD A+ + + +K D+ + K ++
Sbjct: 1407 LNQKCIALEKTKQRLATEVE----DLQLEVDRASSIANAAEKKQKAFDKIIGEWKLKVDD 1462
Query: 3553 IQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQA 3732
+ ++ +E + +S ++ L E+ ++Q + ++ E D+ +I
Sbjct: 1463 LAAELDASQKECR-NYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGR 1521
Query: 3733 SRADIDKKRKIHEAHLMEIQANLAESD-----EHKRTLIDQLERS--RDELDHLNRVREE 3891
+ +I+K RK EA E+QA L E++ E + L QLE S R E+D + +EE
Sbjct: 1522 NIHEIEKSRKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEIDRRIQEKEE 1581
Query: 3892 E-EHAFANMQRRLATAXXXXXXXXXXXXXXTRLKI---ANINRARQLEDEKNALLDE--- 4050
E E+ N QR L + R+K A+IN D N E
Sbjct: 1582 EFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQK 1641
Query: 4051 -----KEEAEGLRAHLEKEIHA---ARQGAGEARRKAEESVNQ---------QLEELRKK 4179
+++ + +++ LE+E A AR+ G + R+A N+ Q + R++
Sbjct: 1642 NIKRYQQQLKDVQSALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRRQ 1701
Query: 4180 NLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKF--- 4350
+++ +QL E I +K+K++ EL+ +L+ + ++SE++ KK
Sbjct: 1702 AEQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDELLNEAKNSEEKAKKAMVD 1761
Query: 4351 ------ESQMAEERVAVQKALLDRDAMSQELRDR----------------------ETRV 4446
E + ++ Q+ L R A+ Q++++ E RV
Sbjct: 1762 AARLADELRAEQDHAQTQEKL--RKALEQQIKELQVRLDEAESNALKGGKKAIQKLEQRV 1819
Query: 4447 LSLLNEVDI-MKEHLE-------------------ESDRVRRSLQQELQDSISNK-DDFG 4563
L +E+D + H + E DR Q+L D + K +
Sbjct: 1820 RELESELDSEQRRHADAQKNLRKSERRIKELTFQSEEDRKNHERMQDLVDKLQQKIKTYK 1879
Query: 4564 KNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDA 4674
+ + E E+ A+ + ++EE E+ IAE A
Sbjct: 1880 RQIEEAEEIAALNLAKFRKAQQELEEAEERADIAEQA 1916
Score = 89.7 bits (221), Expect = 8e-16
Identities = 111/532 (20%), Positives = 233/532 (42%), Gaps = 11/532 (2%)
Frame = +1
Query: 4180 NLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQ 4359
N+ VE +LEE + + ++K+++ELE + +L + + DS +K
Sbjct: 841 NVSRVEDQIAKLEEKATKAQEAYEKEEKLRKELEALNSKLLAEKTALLDSLSGEK---GA 897
Query: 4360 MAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDS 4539
+ E + K ++ + +LRD + R L E D + + ++ L+QE+
Sbjct: 898 LQEYQEKAAKLTAQKNDLENQLRDTQER---LAQEEDARNQLFQ----TKKKLEQEIGSQ 950
Query: 4540 ISNKDDFGKNVHELEKAKRSLEAE---LNDMRVQMEELEDNLQIAEDARLRLEVTNQALK 4710
+ +D + ++E+ K S + + LND +EL + L ++ +++ EV +
Sbjct: 951 KKDAEDLELQIQKIEQDKASKDHQIRNLNDEIAHQDELINKLN--KEKKMQGEVNQKT-- 1006
Query: 4711 SESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
+E +A +K + + L + + +LE+ LE EK+ + ++K+E + ++ +
Sbjct: 1007 AEELQAAEDKVNHLNKVKAKLEQTLDELEDSLEREKKLRGDVEKAKRKVEGDLKLTQEAV 1066
Query: 4891 EVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLR 5070
R K+E + +I A+ ED +L+ + ++ + ++A E+L
Sbjct: 1067 ADLERNKKELEQTVLRK-----DKEISALSAKL--EDEQSLVGKLQKQIKELQARIEELE 1119
Query: 5071 EANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAI 5250
E E QAR AK ++ R LE + + EL
Sbjct: 1120 EEVEAERQAR--------------AKAEKQRADLARELEELGERLEEAGGATSAQIEL-- 1163
Query: 5251 DKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITE-------LESGAQ 5409
+K + +L ++ DL ++ T A +L + + D A++ E L++ A+
Sbjct: 1164 --NKKREAELAKLRRDLEEANIQHEGTLA---NLRKKHNDAVAEMAEQVDQLNKLKTKAE 1218
Query: 5410 SRARAQMAAL-EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQA 5586
A L +A++ DQL+ EK A + A++L+ LN+ + ++ R
Sbjct: 1219 KERTQYFAELNDARIGC--DQLS---NEKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDF 1273
Query: 5587 KELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
+K +++N +L RQL++AE ++S+ ++ ++ +D ++ RE
Sbjct: 1274 DASKKKLSIENSDLLRQLEDAESQVSQLSKIKISLTQQLEDTKRLADEEARE 1325
Score = 79.7 bits (195), Expect = 8e-13
Identities = 81/418 (19%), Positives = 183/418 (43%), Gaps = 25/418 (5%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L +Q+ E ++++ + + LE K +L A LE+++ L ++ KV +L + +E
Sbjct: 1512 LLDQIGEGGRNIHEIEKSRKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQE 1571
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ ++ +EE N ++ Q +D ++ +E E + +A ++++ A + ++
Sbjct: 1572 IDRRIQEKEEEFENTR------KNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINEL 1625
Query: 3451 KGDVLDKVDEATM-LQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+ LD ++A Q + R +++ + A+E+ Q + EQ R+ L +
Sbjct: 1626 E-IALDHANKANAEAQKNIKRYQQQLKDVQSALEEEQRARDDA-REQLGISERRANALQN 1683
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL-- 3801
++E+ + Q ++ + QA+QE +D +++ + A A I ++ E+ L + ++L
Sbjct: 1684 ELEESRTLLEQADRGRRQAEQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDE 1743
Query: 3802 ----AESDEHKRT--------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
A++ E K L D+L +D ++R+ E +Q RL A
Sbjct: 1744 LLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAESN 1803
Query: 3946 XXXXXXXXXXXTRLKIANIN------RARQLEDEKNALLDEKEEAE-GLRAHLEKEIHAA 4104
++ + + R + +KN E+ E ++ +++ H
Sbjct: 1804 ALKGGKKAIQKLEQRVRELESELDSEQRRHADAQKNLRKSERRIKELTFQSEEDRKNHER 1863
Query: 4105 RQGAGEARRKAEESVNQQLEELRK---KNLRDVEHLQKQLEESEVAKERILQSKKKIQ 4269
Q + ++ ++ +Q+EE + NL Q++LEE+E + Q+ K +
Sbjct: 1864 MQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADIAEQAATKFR 1921
Score = 53.9 bits (128), Expect = 5e-05
Identities = 62/408 (15%), Positives = 157/408 (38%), Gaps = 12/408 (2%)
Frame = +1
Query: 2533 QVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAE 2712
++ ++ + A+ DEL+A E + E + E K+ + +E + +++++ + + E
Sbjct: 1525 EIEKSRKRLEAEKDELQAALE---EAEAALEQEENKVLRAQLELSQVRQEIDRRIQEKEE 1581
Query: 2713 LDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXX 2892
+ + + ++ M+ L ++K + +
Sbjct: 1582 ------EFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKA 1635
Query: 2893 XXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHG 3072
+ Q Q A D L +L + +
Sbjct: 1636 NAEAQKNIKRYQQQLKDVQSALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQA 1695
Query: 3073 VKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQL 3252
+ + + E +L + + LN + + KRKL +EL+ L E + + + +
Sbjct: 1696 DRGRRQAEQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDELLNEAKNSEEKA 1755
Query: 3253 MKR-------DEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELRED-METERNARNKA 3408
K +EL+ + + +++Q++++Q +DE + ++ + A K
Sbjct: 1756 KKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAESNALKGGKKAIQKL 1815
Query: 3409 EMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQ 3588
E RE+ ++L+ + D + + + ++ E++Q ++ K++++
Sbjct: 1816 EQRVRELESELDSEQRRHADAQKNLRKSERRIKELTFQSEEDRKNHERMQDLVD-KLQQK 1874
Query: 3589 KAKFSRQVEELHD----QIEQHKKQRSQLEKQQNQADQERADMAQEIA 3720
+ RQ+EE + + + +K + +LE+ + ERAD+A++ A
Sbjct: 1875 IKTYKRQIEEAEEIAALNLAKFRKAQQELEEAE-----ERADIAEQAA 1917
>gi|8393804|ref|NP_058935.1| myosin heavy chain, polypeptide 6; myosin
heavy chain, cardiac muscle, adult; myosin heavy chain,
polypeptide 6, cardiac muscle, alpha; myosin heavy chain
cardiac muscle adult; myosin heavy chain polypeptide 6
cardiac muscle alpha; myosin heavy chain polypeptide 6
cardiac muscle adult [Rattus norvegicus]
gi|127741|sp|P02563|MYH6_RAT Myosin heavy chain, cardiac muscle alpha
isoform (MyHC-alpha)
gi|92498|pir||S06005 myosin alpha heavy chain, cardiac muscle
[similarity] - rat
gi|56655|emb|CAA34064.1| unnamed protein product [Rattus norvegicus]
Length = 1938
Score = 1139 bits (2945), Expect = 0.0
Identities = 659/1898 (34%), Positives = 1061/1898 (55%), Gaps = 20/1898 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
R C+VPD E ++ I +V E + + VT+ D V + NPPKFDKIEDM+
Sbjct: 33 RTECFVPDDKEEYVKAKIVSREGGKVTAE-TENGKTVTVKEDQVMQQNPPKFDKIEDMAM 91
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LT+L+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PP
Sbjct: 92 LTFLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPP 151
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAG-ATRNKSLNAAA 612
HIF+I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A R+K N A
Sbjct: 152 HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRSKKDNPNA 211
Query: 613 QQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYIS 792
+ G LE Q++QANP LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++
Sbjct: 212 NK------------GTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLA 259
Query: 793 GANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYL-----LEGVDNYRFLVN 957
A+IE YLLEKSRV+ Q + ER++HIFYQIL + +K E L +Y F+
Sbjct: 260 SADIETYLLEKSRVIFQLKAERNYHIFYQIL----SNKKPELLDMLLVTNNPYDYAFVSQ 315
Query: 958 RGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAML 1137
+++ ++DD +E +T ++ ++GF +E + + ++ A++ GN++F Q+++ +QA
Sbjct: 316 GEVSVASIDDSEELLATDSAFDVLGFTAEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEP 375
Query: 1138 QDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERL 1317
K +L+GL +L K PR+KVG E+V K Q+ +Q +++ A+AK+ YE++
Sbjct: 376 DGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKSVYEKM 435
Query: 1318 FKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMF 1497
F W+VTRIN +L+ T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF
Sbjct: 436 FNWMVTRINATLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMF 494
Query: 1498 ILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQK 1677
+LEQEEY++EGIEW+FIDFG+DLQ IDLIEKPMG++++L+EEC+FPKA D +F KL
Sbjct: 495 VLEQEEYKKEGIEWEFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLYD 554
Query: 1678 TH-NKHPKFIVP---DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTD 1845
H K F P + ++HF++VHYAG VDY+ WL KN DPLNE VVGL Q S+
Sbjct: 555 NHLGKSNNFQKPRNVKGKQEAHFSLVHYAGTVDYNILGWLEKNKDPLNETVVGLYQKSSL 614
Query: 1846 PFVAGIWKDAEFAGICAAEMNETAFGMRSRK--GMFRTVSQLHKEQLTKLMTTLRNTSPH 2019
+A + F+ +A+ ++ G +K F+TVS LH+E L KLMT LR T PH
Sbjct: 615 KLMATL-----FSTYASADTGDSGKGKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPH 669
Query: 2020 FVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPD 2199
FVRCIIPN K G +++ LV+ QLRCNGVLEGIRICR+GFPNR+ + +FR RY IL P
Sbjct: 670 FVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPA 729
Query: 2200 VIPK-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNF 2376
IP+ FID + K++ +LDID N Y+ G +KVFF+ G+L LEE RD +L+ +I
Sbjct: 730 AIPEGQFIDSGKGAEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRI 789
Query: 2377 QAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDE 2556
QAQ RG L R + N A++ ++NW W +L+ K+KPLL+ T+ E
Sbjct: 790 QAQARGQLMRIEFKKMVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKE 849
Query: 2557 IRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRL 2736
+ +E K+ L K E +E E+K+ ++ E+ +Q Q+Q E +N A+ ++ +L
Sbjct: 850 MANMKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQL 909
Query: 2737 QTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDK 2916
+LE V +M +RL +RK + + +K
Sbjct: 910 IKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 969
Query: 2917 TNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLE 3096
+ + L E++ K+K +LE
Sbjct: 970 HATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKSKVKLE 1029
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
Q+ +LE L +E++ + +LE+ KRKL +L+ +++ + + +L +L K++ ++
Sbjct: 1030 QQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDIS 1089
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
Q ++ ++E A +QK++++ Q I+EL E++E ER AR K E R ++ +LE++
Sbjct: 1090 QQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLTRELEEI-S 1148
Query: 3457 DVLDKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQI 3633
+ L++ AT +Q M++K E E +R +E+ E + K + V EL +QI
Sbjct: 1149 ERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQI 1208
Query: 3634 EQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESD 3813
+ ++ + +LEK++++ E D+ + + ++A+++K + E E + L E+
Sbjct: 1209 DNLQRVKQKLEKEKSEFKLELDDVTSHMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQ 1268
Query: 3814 EHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKI 3993
Q + + E L R EE+E + R + + K
Sbjct: 1269 RSLNDFTTQRAKLQTENGELARQLEEKEALIWQLTRGKLSYTQQMEDLKRQLEEEGKAKN 1328
Query: 3994 ANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELR 4173
A + + + + L ++ EE +A L++ + A + R K E Q+ EEL
Sbjct: 1329 ALAHALQSARHDCDLLREQYEEEMEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELE 1388
Query: 4174 KKNLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQK 4344
+ + + LQ E E + + ++K ++Q E+ED +++E A+ +K+Q+
Sbjct: 1389 EAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR 1448
Query: 4345 KFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQ 4524
F+ +AE + +++ + ++ +E R T + L N + EHLE R ++LQ+
Sbjct: 1449 NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQE 1508
Query: 4525 ELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQA 4704
E+ D + GKNVHELEK ++ LE E +++ +EE E +L+ E LR ++
Sbjct: 1509 EISDLTEQLGEGGKNVHELEKIRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQ 1568
Query: 4705 LKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQ 4884
+K+E +R ++ KD E E+ +R L+ + L+ L+ E R ++ A+ +KK+E + E+E
Sbjct: 1569 IKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEI 1628
Query: 4885 QLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQ 5064
QL ANR+ E + Q++ ++A +A +D+ + +R+ ++AE E+
Sbjct: 1629 QLSQANRIASEAQKHLKNAQAHLKDTQLQLDDAVRANDDLKENIAIVERRNTLLQAELEE 1688
Query: 5065 LREANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSN 5235
LR E ++RK Q +K++++A ++Q
Sbjct: 1689 LRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQE 1748
Query: 5236 CELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSR 5415
C A +K +KA + +L E+ + E K+++E++ +D + ++ E E A
Sbjct: 1749 CRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKG 1808
Query: 5416 ARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKEL 5595
+ Q+ LEA+V+ LE++L E + + + R+ E+R+ + T Q E++K+ + ++L
Sbjct: 1809 GKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLVRLQDL 1868
Query: 5596 LEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
++K LK + +RQ +EAE++ + +K R VQ E D+
Sbjct: 1869 VDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDE 1906
Score = 148 bits (373), Expect = 2e-33
Identities = 183/873 (20%), Positives = 370/873 (41%), Gaps = 17/873 (1%)
Frame = +1
Query: 3181 AELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTID 3360
AE E ++ E+ G+V++ + R +EL+ ++ V+L+Q++ +
Sbjct: 844 AETEKEMANMKEEFGRVKDALEKSEARRKELEEKM---------VSLLQEK--------N 886
Query: 3361 ELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT-MLQDLMSRKDEEVNATK 3537
+L+ ++ E++ AE E QL K K + KV E T L+D +EE+NA
Sbjct: 887 DLQLQVQAEQDNLADAE----ERCDQLIKNKIQLEAKVKEMTERLED-----EEEMNA-- 935
Query: 3538 RAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEI 3717
++ +K K + EL I+ + +++EK+++ + + ++ +E+
Sbjct: 936 ------------ELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEM 983
Query: 3718 ALLQASRADIDKKRK-IHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEE 3894
A L A + K++K + EAH + AE D+ TL + ++D L E+E
Sbjct: 984 AGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK-VNTLTKSKVKLEQQVDDLEGSLEQE 1042
Query: 3895 EHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLR 4074
+ +++R R+LE + + + E +
Sbjct: 1043 KKVRMDLERA----------------------------KRKLEGDLKLTQESIMDLENDK 1074
Query: 4075 AHLEKEIHAARQGAGEARRKAEE--SVNQQLEELRKKNLRDVEHLQKQLEESEVAKERIL 4248
LE+++ + K E+ ++ QL++ K+N +E L+++LE A+ ++
Sbjct: 1075 LQLEEKLKKKEFDISQQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVE 1134
Query: 4249 QSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELR 4428
+ + + +ELE+ S LE + + KK E++ + R +++A L +A + LR
Sbjct: 1135 KLRSDLTRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALR 1194
Query: 4429 DRETRVLSLLNE-VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLE 4605
+ ++ L E +D ++ ++ ++ + + EL D S+ + K LEK R+LE
Sbjct: 1195 KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSHMEQIIKAKANLEKVSRTLE 1254
Query: 4606 AELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLL--- 4776
+ N+ RV++EE + +L R +L+ N E R + K+ + RG L
Sbjct: 1255 DQANEYRVKLEEAQRSLNDFTTQRAKLQTEN----GELARQLEEKEALIWQLTRGKLSYT 1310
Query: 4777 KQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXX 4956
+Q+ DL+ +LE E + K+ + + L +Q E K E
Sbjct: 1311 QQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEEMEAKAELQRVLSKANSEVA 1370
Query: 4957 EYQIE--------CEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXX 5112
+++ + EE +AK+ +A L++A+ AV A+ L + R Q
Sbjct: 1371 QWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKH-----RLQNE 1425
Query: 5113 XXXXXXXXXRAKGGGISSEEKRRLEAKI-AQXXXXXXXXQSNCELAIDKQRKAQVQLEQI 5289
R+ + ++K+R KI A+ QS E +Q + +
Sbjct: 1426 IEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE-------SSQKEARSL 1478
Query: 5290 TTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQ 5469
+T+L + +++ ++ +R N++ + +I++L + + +++ + Q
Sbjct: 1479 STELFKLKNAYEESLEHLETFKRENKNLQEEISDL-----TEQLGEGGKNVHELEKIRKQ 1533
Query: 5470 LNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEA 5649
L VE E L+ L + E E+ +A+ LE + +K + R+L E
Sbjct: 1534 LEVEKLE----------LQSALEEAEASLEHEEGKILRAQ--LEFNQIK-AEIERKLAEK 1580
Query: 5650 EDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
++EM + + H V LDA + E +
Sbjct: 1581 DEEMEQAKRNHLRVVDSLQTSLDAETRSRNEAL 1613
Score = 129 bits (325), Expect = 7e-28
Identities = 145/755 (19%), Positives = 315/755 (41%), Gaps = 44/755 (5%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + + D +E+ + +R +LE++ QE+ D+ ++ Q + AD ++
Sbjct: 847 EKEMANMKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERC 906
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ L + +E L + + DE L + ++ E A ++
Sbjct: 907 DQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVE 966
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ K A N+ + L +E A LDE + A L KE
Sbjct: 967 KE---------------------KHATENKVKNLTEEM-AGLDE------IIAKLTKEKK 998
Query: 4099 AARQGAGEARR--KAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQ 4272
A ++ +A +AEE L + + K + V+ L+ LE+ + + + ++K+K++
Sbjct: 999 ALQEAHQQALDDLQAEEDKVNTLTKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEG 1058
Query: 4273 EL---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETR 4443
+L ++S M+LEN + + K+ K+F+ ++ ++AL + + ++L++ + R
Sbjct: 1059 DLKLTQESIMDLENDKLQLEEKLKK-KEFDISQQNSKIEDEQALALQ--LQKKLKENQAR 1115
Query: 4444 VLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDM 4623
+ L E++ + + +++R L +EL++ ++ G + + EAE M
Sbjct: 1116 IEELEEELEAERTARAKVEKLRSDLTRELEEISERLEEAGGATSVQIEMNKKREAEFQKM 1175
Query: 4624 RVQME----------------------ELEDNLQIAEDARLRLEVTNQALKSESDRAISN 4737
R +E EL + + + + +LE K E D S+
Sbjct: 1176 RRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSH 1235
Query: 4738 KD--VEAEEKRRGLLKQIRDLENE----LENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
+ ++A+ + + + D NE LE +R + + R K++ + GEL +QLE
Sbjct: 1236 MEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEK 1295
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA----DRKFRAVEAEREQL 5067
L + + + + EE +AK +A L+ A D E E E
Sbjct: 1296 EALIWQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEEMEAK 1355
Query: 5068 REANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELA 5247
E L +A + + E K++L ++ + C
Sbjct: 1356 AELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSL 1415
Query: 5248 IDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQ 5427
+ + Q ++E + D+ + ++++ ++ ++K K E +S +S ++ +
Sbjct: 1416 EKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELES-SQKE 1474
Query: 5428 MAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKS 5607
+L ++ L++ + R + L++ ++D T+Q + + + +++ ++
Sbjct: 1475 ARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKIRKQL 1534
Query: 5608 NLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
++ L+ L+EAE + E K Q E + +
Sbjct: 1535 EVEKLELQSALEEAEASLEHEEGKILRAQLEFNQI 1569
Score = 96.3 bits (238), Expect = 8e-18
Identities = 127/575 (22%), Positives = 257/575 (44%), Gaps = 42/575 (7%)
Frame = +1
Query: 3046 DHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMG 3225
D +R + +AK +L +L + E+ + S LE+ K +L E+ED +
Sbjct: 1379 DAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNA 1438
Query: 3226 KVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELR-------EDMET 3384
L+ + D+ L +Y+E + + QK+ R + T + +L+ E +ET
Sbjct: 1439 AAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLET 1498
Query: 3385 -ERNARNKAE----MTRR-----EVVAQLEKVKGDV-LDKVDEATMLQDL---------- 3501
+R +N E +T + + V +LEK++ + ++K++ + L++
Sbjct: 1499 FKRENKNLQEEISDLTEQLGEGGKNVHELEKIRKQLEVEKLELQSALEEAEASLEHEEGK 1558
Query: 3502 MSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQ 3681
+ R E N K IE+ + ++E+ K R V+ L ++ + R++ + + +
Sbjct: 1559 ILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKK 1618
Query: 3682 ADQERADMAQEIALLQASR--ADIDKKRKIHEAHLMEIQANLAE----SDEHKRTLIDQL 3843
+ + +M EI L QA+R ++ K K +AHL + Q L + +D+ K +
Sbjct: 1619 MEGDLNEM--EIQLSQANRIASEAQKHLKNAQAHLKDTQLQLDDAVRANDDLKENIAIVE 1676
Query: 3844 ERS---RDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRAR 4014
R+ + EL+ L V E+ E + R+LA + IN+ +
Sbjct: 1677 RRNTLLQAELEELRAVVEQTERS-----RKLAEQELIETSERVQLLHSQNTSL--INQKK 1729
Query: 4015 QLEDEKNALLDEKEEA-EGLRAHLEKEIHAARQGAGEARR-KAEESVNQQLEELRKKNLR 4188
+++ + + L E EEA + R EK A A A K E+ + LE ++K +
Sbjct: 1730 KMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQ 1789
Query: 4189 DVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAE 4368
++ LQ +L+E+E + L+ KK Q+LE ELEN + E QK+ +
Sbjct: 1790 TIKDLQHRLDEAE---QIALKGGKKQLQKLEARVRELEN------ELEAEQKRNAESVKG 1840
Query: 4369 ERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISN 4548
R + ++ + + ++E + R+ L++++ + + +R ++ + + +N
Sbjct: 1841 MRKS-ERRIKELTYQTEEDKKNLVRLQDLVDKLQL------KVKAYKRQAEEAEEQANTN 1893
Query: 4549 KDDFGKNVHELEKAKRS---LEAELNDMRVQMEEL 4644
F K HEL++A+ E+++N +R + ++
Sbjct: 1894 LSKFRKVQHELDEAEERADIAESQVNKLRAKSRDI 1928
>gi|29727|emb|CAA37068.1| cardiac beta myosin heavy chain [Homo
sapiens]
Length = 1934
Score = 1139 bits (2945), Expect = 0.0
Identities = 665/1896 (35%), Positives = 1066/1896 (56%), Gaps = 18/1896 (0%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K +VPD + F+ I +V E + + VT+ D V + NPPKFDKIEDM+
Sbjct: 34 KKDVFVPDDKQEFVKAKIVSREGGKVTAE-TEYGKTVTVKEDQVMQQNPPKFDKIEDMAM 92
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LT+L+E +VL+NLK+RY S +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PP
Sbjct: 93 LTFLHEPAVLYNLKERYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPP 152
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIF+I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A A ++S
Sbjct: 153 HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIA-AIGDRS------ 205
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
K D G LE Q++QANP LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++
Sbjct: 206 -----KKDQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLAS 260
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYL-----LEGVDNYRFLVNR 960
A+IE YLLEKSRV+ Q + ER +HIFYQIL + +K E L +Y F+
Sbjct: 261 ADIETYLLEKSRVIFQLKAERDYHIFYQIL----SNKKPELLDMLLITNNPYDYAFISQG 316
Query: 961 GITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQ 1140
T+ ++DD +E +T N+ ++GF +E +S+ ++ A++ GN++F +++ +QA
Sbjct: 317 ETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPD 376
Query: 1141 DDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLF 1320
K +L+GL +L K PR+KVG E+V K QN +Q +A A+AKA YER+F
Sbjct: 377 GTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMF 436
Query: 1321 KWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFI 1500
W+VTRIN +L+ T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF+
Sbjct: 437 NWMVTRINATLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFV 495
Query: 1501 LEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKT 1680
LEQEEY++EGIEW FIDFG+DLQ IDLIEKPMG++++L+EEC+FPKA D +F KL
Sbjct: 496 LEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLFDN 555
Query: 1681 H-NKHPKFIVP---DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDP 1848
H K F P + ++HF+++HYAG VDY+ WL KN DPLNE VVGL Q S+
Sbjct: 556 HLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLK 615
Query: 1849 FVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVR 2028
++ ++ A +AG A E G + F+TVS LH+E L KLMT LR+T PHFVR
Sbjct: 616 LLSTLF--ANYAG--ADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVR 671
Query: 2029 CIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIP 2208
PN K G +++ LV+ QLRCNGVLEGIRICR+GFPNR+ + +FR RY IL P IP
Sbjct: 672 LYHPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIP 731
Query: 2209 K-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQ 2385
+ FID ++ K++++LDID N Y+ G +KVFF+ G+L LEE RD +L+ +I QAQ
Sbjct: 732 EGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQ 791
Query: 2386 CRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRA 2565
RG L+R Y N A++ ++NW W +L+ K+KPLL+ + E+ +
Sbjct: 792 SRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAEREKEMAS 851
Query: 2566 KDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTR 2745
+E A KE L K E +E E+K+ ++ E+ +Q Q+Q E +N A+ ++ +L
Sbjct: 852 MKEEFTALKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKN 911
Query: 2746 NQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNV 2925
+LE V +M +RL +R + + +K
Sbjct: 912 KIQLEAKVKEMNERLEDEEEMNAELTAKKRNVEDECSELKRDIDDLELTLAKVEKEKHAT 971
Query: 2926 DQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQL 3105
+ + L E++ KAK +LE Q+
Sbjct: 972 ENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQV 1031
Query: 3106 HELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQL 3285
+LE L +E++ + +LE+ KRKL +L+ +++ + + ++L+ +L K+D EL
Sbjct: 1032 DDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALN 1091
Query: 3286 TRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVL 3465
R ++E A + +QK+++++Q I+EL E++E ER AR K E R ++ +LE++ + L
Sbjct: 1092 ARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEI-SERL 1150
Query: 3466 DKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQH 3642
++ AT Q M++K E E +R +E+ E + K + V EL +QI+
Sbjct: 1151 EEAGGATSCQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 1210
Query: 3643 KKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHK 3822
++ + +LEK++++ E D+ + + ++A+++K + E + E ++ E+
Sbjct: 1211 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSV 1270
Query: 3823 RTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANI 4002
L Q + + E L+R +E+E + + R T + K A
Sbjct: 1271 NDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALA 1330
Query: 4003 NRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN 4182
+ + + + L ++ EE +A L++ + A + R K E Q+ EEL +
Sbjct: 1331 HALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAK 1390
Query: 4183 LRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFE 4353
+ + LQ+ E E + + ++K ++Q E+ED +++E A+ +K+Q+ F+
Sbjct: 1391 KKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFD 1450
Query: 4354 SQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQ 4533
+AE + +++ + ++ +E R T + L N + EHLE R ++LQ+E+
Sbjct: 1451 KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEIS 1510
Query: 4534 DSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKS 4713
D GK +HELEK ++ LEAE +++ +EE E +L+ E LR ++ +K+
Sbjct: 1511 DLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKA 1570
Query: 4714 ESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLE 4893
E +R ++ KD E E+ +R L+ + L+ L+ E R ++ A+ +KK+E + E+E QL
Sbjct: 1571 EIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLS 1630
Query: 4894 VANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLRE 5073
ANR+ E + QI+ ++A +A +D+ + +R+ ++AE E+LR
Sbjct: 1631 HANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERR-NNLQAELEELRA 1689
Query: 5074 ANEGLMQARK----QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCE 5241
E ++RK + ++ + + +K++++A ++Q C
Sbjct: 1690 VVEQTERSRKLADRELIETSERVQLLHSQNTSLIN-QKKKMDADLSQLQTEVEEAVQECR 1748
Query: 5242 LAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRAR 5421
A +K +KA + +L E+ + E K+++E++ +D + ++ E E A +
Sbjct: 1749 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGK 1808
Query: 5422 AQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLE 5601
Q+ LEA+V+ LE++L E + + + R+ E+R+ + T Q E++++ + ++L++
Sbjct: 1809 KQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVD 1868
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
K LK + +RQ +EAE++ + +K R VQ E D+
Sbjct: 1869 KLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDE 1904
Score = 150 bits (379), Expect = 4e-34
Identities = 169/837 (20%), Positives = 361/837 (42%), Gaps = 29/837 (3%)
Frame = +1
Query: 3325 QKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLM 3504
+K+M M+ L+E +E K+E R+E+ EK+ + +K D +Q
Sbjct: 846 EKEMASMKEEFTALKEALE-------KSEARRKELE---EKMVSLLQEKNDLQLQVQ--- 892
Query: 3505 SRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQA 3684
+ +D +A +R + I++ K + +V+E+++++E ++ ++L ++
Sbjct: 893 AEQDNLADAEERCDQLIKN---------KIQLEAKVKEMNERLEDEEEMNAELTAKKRNV 943
Query: 3685 DQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDE-------HKRTL---- 3831
+ E +++ ++I L+ + A ++K++ E + + +A DE K+ L
Sbjct: 944 EDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAH 1003
Query: 3832 ---IDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANI 4002
+D L+ D+++ L + + + E +++ L R+ +
Sbjct: 1004 QQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKK------------VRMDLERA 1051
Query: 4003 NRARQ--LEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRK 4176
R + L+ + +++D + + + L L+K+ A AR + E+++ QL++ K
Sbjct: 1052 KRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELN--ALNARIEDEQALGSQLQKKLK 1109
Query: 4177 KNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFES 4356
+ +E L+++LE A+ ++ + + + +ELE+ S LE + + KK E+
Sbjct: 1110 ELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSCQIEMNKKREA 1169
Query: 4357 QMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNE-VDIMKEHLEESDRVRRSLQQELQ 4533
+ + R +++A L +A + LR + ++ L E +D ++ ++ ++ + + EL
Sbjct: 1170 EFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELD 1229
Query: 4534 DSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKS 4713
D SN + K LEK R+LE ++N+ R + EE + ++ R +L+ N
Sbjct: 1230 DVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTEN----G 1285
Query: 4714 ESDRAISNKDVEAEEKRRGLL---KQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQ 4884
E R + K+ + RG L +Q+ DL+ +LE E + K+ + + L +
Sbjct: 1286 ELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLRE 1345
Query: 4885 QLEVANRLKEEYXXXXXXXXXXXXEYQIE--------CEEARQAKEDIAALLREADRKFR 5040
Q E K E +++ + EE +AK+ +A L+EA+
Sbjct: 1346 QYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVE 1405
Query: 5041 AVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKI-AQXXXXX 5217
AV A+ L + R Q R+ + ++K+R KI A+
Sbjct: 1406 AVNAKCSSLEKTKH-----RLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKY 1460
Query: 5218 XXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELE 5397
QS E +Q + ++T+L + +++ ++ +R N++ + +I++L
Sbjct: 1461 EESQSELE-------SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLT 1513
Query: 5398 SGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRAN 5577
S + +++ + QL E E L+ L + E E+
Sbjct: 1514 EQLGSSGKTIH-----ELEKVRKQLEAEKME----------LQSALEEAEASLEHEEGKI 1558
Query: 5578 EQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
+A+ LE + +K + R+L E ++EM + + H V LDA + E +
Sbjct: 1559 LRAQ--LEFNQIK-AEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEAL 1612
Score = 137 bits (344), Expect = 4e-30
Identities = 166/833 (19%), Positives = 344/833 (40%), Gaps = 50/833 (6%)
Frame = +1
Query: 3364 LREDMETERNAR--NKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ----DLMSRKDEEV 3525
L E+M ER +R + + R V+A++E K +L++ D ++Q M K+
Sbjct: 772 LLEEMRDERLSRIITRIQAQSRGVLARMEYKK--LLERRDSLLVIQWNIRAFMGVKNWPW 829
Query: 3526 NATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADM 3705
I+ + + E E++ A + L + +E+ + +R +LE++ QE+ D+
Sbjct: 830 MKLYFKIKPLLKSAER--EKEMASMKEEFTALKEALEKSEARRKELEEKMVSLLQEKNDL 887
Query: 3706 AQEIALLQASRADIDK------KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDEL 3864
++ Q + AD ++ K KI EA + E+ L + +E L + DE
Sbjct: 888 QLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRNVEDEC 947
Query: 3865 DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALL 4044
L R ++ E A +++ K A N+ + L +E A L
Sbjct: 948 SELKRDIDDLELTLAKVEKE---------------------KHATENKVKNLTEEM-AGL 985
Query: 4045 DEKEEAEGLRAHLEKEIHAARQGAGEARR--KAEESVNQQLEELRKKNLRDVEHLQKQLE 4218
DE + A L KE A ++ +A +AEE L + + K + V+ L+ LE
Sbjct: 986 DE------IIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLE 1039
Query: 4219 ESEVAKERILQSKKKIQQEL---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQK 4389
+ + + + ++K+K++ +L ++S M+LEN + D ++K FE R+ ++
Sbjct: 1040 QEKKVRMDLERAKRKLEGDLKLTQESIMDLENDK-QQLDERLKKKDFELNALNARIEDEQ 1098
Query: 4390 ALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKN 4569
AL + + ++L++ + R+ L E++ + + +++R L +EL++ ++ G
Sbjct: 1099 ALGSQ--LQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGA 1156
Query: 4570 VHELEKAKRSLEAELNDMRVQMEE----------------------LEDNLQIAEDARLR 4683
+ + EAE MR +EE L + + + + +
Sbjct: 1157 TSCQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQK 1216
Query: 4684 LEVTNQALKSESDRAISNKD------VEAEEKRRGLLKQIRDLENELENEKRGKSGAVSH 4845
LE K E D SN + E+ R L Q+ + ++ E +R + S
Sbjct: 1217 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 1276
Query: 4846 RKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA 5025
R K++ + GEL +QL+ L + + + + EE +AK +A L+ A
Sbjct: 1277 RAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSA 1336
Query: 5026 ----DRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAK 5193
D E E E E L +A + + E K++L +
Sbjct: 1337 RHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1396
Query: 5194 IAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDY 5373
+ + + C + + Q ++E + D+ + ++++ ++ ++
Sbjct: 1397 LQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEW 1456
Query: 5374 KAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQ 5553
K K E +S +S ++ + +L ++ L++ + R + L++ ++D T+Q
Sbjct: 1457 KQKYEESQSELES-SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQ 1515
Query: 5554 FEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ + +++ ++ + L+ L+EAE + E K Q E + +
Sbjct: 1516 LGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQI 1568
>gi|476355|pir||A46762 myosin alpha heavy chain, cardiac muscle -
human
gi|219524|dbj|BAA00791.1| cardiac alpha-myosin heavy chain [Homo
sapiens]
Length = 1939
Score = 1138 bits (2944), Expect = 0.0
Identities = 657/1899 (34%), Positives = 1063/1899 (55%), Gaps = 21/1899 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
R C+VPD E F+ I +V+ E + + VT+ D V + NPPKFDKIEDM+
Sbjct: 34 RTECFVPDDKEEFVKAKILSREGGKVIAE-TENGKTVTVKEDQVLQQNPPKFDKIEDMAM 92
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LT+L+E +VL NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PP
Sbjct: 93 LTFLHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPP 152
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAG-ATRNKSLNAAA 612
HIF+I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A R K NA A
Sbjct: 153 HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNANA 212
Query: 613 QQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYIS 792
+ G LE Q++QANP LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++
Sbjct: 213 NK------------GTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLA 260
Query: 793 GANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYL-----LEGVDNYRFLVN 957
A+IE YLLEKSRV+ Q + ER++HIFYQIL + +K E L +Y F+
Sbjct: 261 SADIETYLLEKSRVIFQLKAERNYHIFYQIL----SNKKPELLDMLLVTNNPYDYAFVSQ 316
Query: 958 RGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAML 1137
+++ ++DD +E +T ++ ++GF +E + + ++ A++ GN++F Q+++ +QA
Sbjct: 317 GEVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEP 376
Query: 1138 QDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERL 1317
K +L+GL +L K PR+KVG E+V K Q+ +Q +++ A+AKA YE++
Sbjct: 377 DGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKM 436
Query: 1318 FKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMF 1497
F W+VTRIN +L+ T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF
Sbjct: 437 FNWMVTRINATLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMF 495
Query: 1498 ILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQK 1677
+LEQEEY++EGIEW FIDFG+DLQ IDLIEKPMG++++L+EEC+FPKA D +F KL
Sbjct: 496 VLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLYD 555
Query: 1678 TH-NKHPKFIVP---DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTD 1845
H K F P + ++HF+++HYAG VDY+ WL KN DPLNE VVGL Q S+
Sbjct: 556 NHLGKSNNFQKPRNIKGKPEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVGLYQKSSL 615
Query: 1846 PFVAGIWKDAEFAGICAAEMNET--AFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPH 2019
+A + F+ A+ ++ + G + + F+TVS LH+E L KLMT LR T PH
Sbjct: 616 KLMATL-----FSSYATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPH 670
Query: 2020 FVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPD 2199
FVRCIIPN K G +++ LV+ QLRCNGVLEGIRICR+GFPNR+ + +FR RY IL P
Sbjct: 671 FVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPV 730
Query: 2200 VIPK-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNF 2376
IP+ FID ++ K++++LDID N Y+ G +KVFF+ G+L LEE RD +L+ +I
Sbjct: 731 AIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRI 790
Query: 2377 QAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDE 2556
QAQ RG L R + N A++ ++NW W +L+ K+KPLL+ T+ E
Sbjct: 791 QAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKE 850
Query: 2557 IRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRL 2736
+ +E KE L K E +E E+K+ ++ E+ +Q Q+Q E +N + ++ +L
Sbjct: 851 MATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQL 910
Query: 2737 QTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDK 2916
+LE V +M +RL +RK + + +K
Sbjct: 911 IKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 970
Query: 2917 TNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLE 3096
+ + L E++ K+K +LE
Sbjct: 971 HATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLSKSKVKLE 1030
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
Q+ +LE L +E++ + +LE+ KRKL +L+ +++ + + +L +L K++ ++
Sbjct: 1031 QQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDIN 1090
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
Q ++ ++E +QK++++ Q I+EL E++E ER AR K E R ++ +LE++
Sbjct: 1091 QQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEI-S 1149
Query: 3457 DVLDKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQI 3633
+ L++ AT +Q M++K E E +R +E+ E + K + V EL +QI
Sbjct: 1150 ERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQI 1209
Query: 3634 EQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESD 3813
+ ++ + +LEK++++ E D+ + + ++A+++K + E E + L E+
Sbjct: 1210 DNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQ 1269
Query: 3814 EHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKI 3993
Q + + E L+R EE+E + + R + + K
Sbjct: 1270 RSLNDFTTQRAKLQTENGELSRQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKN 1329
Query: 3994 ANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELR 4173
A + + + + L ++ EE +A L++ + A + R K E Q+ EEL
Sbjct: 1330 ALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQCRTKYETDAIQRTEELE 1389
Query: 4174 KKNLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQK 4344
+ + + LQ E E + + ++K ++Q E+ED +++E A+ +K+Q+
Sbjct: 1390 EAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR 1449
Query: 4345 KFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQ 4524
F+ +AE + +++ + ++ +E R T + L N + EHLE R ++LQ+
Sbjct: 1450 NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQE 1509
Query: 4525 ELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQA 4704
E+ D + GKNVHELEK ++ LE E +++ +EE E +L+ E LR ++
Sbjct: 1510 EISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQ 1569
Query: 4705 LKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQ 4884
+K+E +R ++ KD E E+ +R + + L+ L+ E R ++ + +KK+E + E+E
Sbjct: 1570 IKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEI 1629
Query: 4885 QLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQ 5064
QL ANR+ E + QI+ ++A +A +D+ + +R+ ++AE E+
Sbjct: 1630 QLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEE 1689
Query: 5065 LREANEGLMQARK----QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQS 5232
LR E ++RK + ++ + + +K++++A ++Q
Sbjct: 1690 LRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLIN-QKKKMDADLSQLQSEVEEAVQ 1748
Query: 5233 NCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQS 5412
C A +K +KA + +L E+ + E K+++E++ +D + ++ E E A
Sbjct: 1749 ECRNAEEKAKKAITHAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALK 1808
Query: 5413 RARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKE 5592
+ Q+ LEA+V+ LE +L E + + + R+ E+R+ + T Q E++K+ + ++
Sbjct: 1809 GGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQD 1868
Query: 5593 LLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
L++K LK + +RQ +EAE++ + +K R VQ E D+
Sbjct: 1869 LVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDE 1907
Score = 154 bits (388), Expect = 3e-35
Identities = 187/875 (21%), Positives = 367/875 (41%), Gaps = 19/875 (2%)
Frame = +1
Query: 3181 AELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTID 3360
AE E + E+ G+++E + R +EL+ ++ V+L+Q++ +
Sbjct: 845 AETEKEMATMKEEFGRIKETLEKSEARRKELEEKM---------VSLLQEK--------N 887
Query: 3361 ELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT-MLQDLMSRKDEEVNATK 3537
+L+ ++ E++ N AE E QL K K + KV E L+D +EE+NA
Sbjct: 888 DLQLQVQAEQDNLNDAE----ERCDQLIKNKIQLEAKVKEMNERLED-----EEEMNA-- 936
Query: 3538 RAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEI 3717
++ +K K + EL I+ + +++EK+++ + + ++ +E+
Sbjct: 937 ------------ELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEM 984
Query: 3718 ALLQASRADIDKKRK-IHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEE 3894
A L A + K++K + EAH + AE D+ TL + ++D L E+E
Sbjct: 985 AGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK-VNTLSKSKVKLEQQVDDLEGSLEQE 1043
Query: 3895 EHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLR 4074
+ +++R R+LE + + + E +
Sbjct: 1044 KKVRMDLERA----------------------------KRKLEGDLKLTQESIMDLENDK 1075
Query: 4075 AHLEKEIHAARQGAGEARRKAEES--VNQQLEELRKKNLRDVEHLQKQLEESEVAKERIL 4248
LE+++ + K E+ + QL++ K+N +E L+++LE A+ ++
Sbjct: 1076 LQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVE 1135
Query: 4249 QSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELR 4428
+ + + +ELE+ S LE + + KK E++ + R +++A L +A + LR
Sbjct: 1136 KLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALR 1195
Query: 4429 DRETRVLSLLNE-VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLE 4605
+ ++ L E +D ++ ++ ++ + + EL D SN + K LEK R+LE
Sbjct: 1196 KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLE 1255
Query: 4606 AELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLL--- 4776
+ N+ RV++EE + +L R +L+ N E R + K+ + RG L
Sbjct: 1256 DQANEYRVKLEEAQRSLNDFTTQRAKLQTEN----GELSRQLEEKEALISQLTRGKLSYT 1311
Query: 4777 KQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXX 4956
+Q+ DL+ +LE E + K+ + + L +Q E K E
Sbjct: 1312 QQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVA 1371
Query: 4957 E----YQIEC----EEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXX 5112
+ Y+ + EE +AK+ +A L++A+ AV A+ L + R Q
Sbjct: 1372 QCRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKH-----RLQNE 1426
Query: 5113 XXXXXXXXXRAKGGGISSEEKRRLEAKI-AQXXXXXXXXQSNCELAIDKQRKAQVQLEQI 5289
R+ + ++K+R KI A+ QS E +Q + +
Sbjct: 1427 IEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE-------SSQKEARSL 1479
Query: 5290 TTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQ 5469
+T+L + +++ ++ +R N++ + +I++L Q E
Sbjct: 1480 STELFKLKNAYEESLEHLETFKRENKNLQEEISDLTE-----------------QLGEGG 1522
Query: 5470 LNVEGQEKTAANRAARRLEKR--LNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLD 5643
NV EK +LE + L + E E+ +A+ LE + +K + R+L
Sbjct: 1523 KNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQ--LEFNQIK-AEIERKLA 1579
Query: 5644 EAEDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
E ++EM + + H+ V LDA + E++
Sbjct: 1580 EKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVL 1614
Score = 128 bits (322), Expect = 1e-27
Identities = 143/755 (18%), Positives = 313/755 (40%), Gaps = 44/755 (5%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + + + +E+ + +R +LE++ QE+ D+ ++ Q + D ++
Sbjct: 848 EKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERC 907
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ L + +E L + + DE L + ++ E A ++
Sbjct: 908 DQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVE 967
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ K A N+ + L +E A LDE + A L KE
Sbjct: 968 KE---------------------KHATENKVKNLTEEM-AGLDE------IIAKLTKEKK 999
Query: 4099 AARQGAGEARR--KAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQ 4272
A ++ +A +AEE L + + K + V+ L+ LE+ + + + ++K+K++
Sbjct: 1000 ALQEAHQQALDDLQAEEDKVNTLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEG 1059
Query: 4273 EL---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETR 4443
+L ++S M+LEN + + K+ K+F+ ++ ++ L + + ++L++ + R
Sbjct: 1060 DLKLTQESIMDLENDKLQLEEKLKK-KEFDINQQNSKIEDEQVLALQ--LQKKLKENQAR 1116
Query: 4444 VLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDM 4623
+ L E++ + + +++R L +EL++ ++ G + + EAE M
Sbjct: 1117 IEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKM 1176
Query: 4624 RVQME----------------------ELEDNLQIAEDARLRLEVTNQALKSESDRAISN 4737
R +E EL + + + + +LE K E D SN
Sbjct: 1177 RRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 1236
Query: 4738 KD--VEAEEKRRGLLKQIRDLENE----LENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
+ ++A+ + + + D NE LE +R + + R K++ + GEL +QLE
Sbjct: 1237 MEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELSRQLEEK 1296
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA----DRKFRAVEAEREQL 5067
L + + + + EE +AK +A L+ A D E E E
Sbjct: 1297 EALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAK 1356
Query: 5068 REANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELA 5247
E L +A + + E K++L ++ + C
Sbjct: 1357 AELQRVLSKANSEVAQCRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSL 1416
Query: 5248 IDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQ 5427
+ + Q ++E + D+ + ++++ ++ ++K K E +S +S ++ +
Sbjct: 1417 EKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELES-SQKE 1475
Query: 5428 MAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKS 5607
+L ++ L++ + R + L++ ++D T+Q + + + +++ ++
Sbjct: 1476 ARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQL 1535
Query: 5608 NLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
++ L+ L+EAE + E K Q E + +
Sbjct: 1536 EVEKLELQSALEEAEASLEHEEGKILRAQLEFNQI 1570
Score = 97.4 bits (241), Expect = 4e-18
Identities = 110/560 (19%), Positives = 243/560 (42%), Gaps = 27/560 (4%)
Frame = +1
Query: 3046 DHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMG 3225
D +R + +AK +L +L + E+ + S LE+ K +L E+ED +
Sbjct: 1380 DAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNA 1439
Query: 3226 KVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELR---EDMETERNA 3396
L+ + D+ L +Y+E + + QK+ R + T + +L+ E+
Sbjct: 1440 AAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLET 1499
Query: 3397 RNKAEMTRREVVAQLEKVKGDVLDKVDEATML-QDLMSRKDEEVNATKRAIEQIQHTMEG 3573
+ +E ++ L + G+ V E + + L K E +A + A ++H EG
Sbjct: 1500 FKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHE-EG 1558
Query: 3574 KI-------EEQKAKFSRQVEELHDQIEQHKKQRSQ-LEKQQNQADQERADMAQEIALLQ 3729
KI + KA+ R++ E +++EQ K+ + ++ Q D E + + + +
Sbjct: 1559 KILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKK 1618
Query: 3730 ASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFA 3909
D+++ E L AE+ + ++L L+ ++ +LD R ++ + A
Sbjct: 1619 KMEGDLNEM----EIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIA 1674
Query: 3910 NMQRR-------LATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEG 4068
++RR L R I R + L + +L+++K++ +
Sbjct: 1675 IVERRNNLLQAELEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDA 1734
Query: 4069 LRAHLEKEIHAARQGAGEARRKAEESVN---QQLEELRKK--NLRDVEHLQKQLEESEVA 4233
+ L+ E+ A Q A KA++++ EEL+K+ +E ++K +E++
Sbjct: 1735 DLSQLQSEVEEAVQECRNAEEKAKKAITHAAMMAEELKKEQDTSAHLERMKKNMEQTIKD 1794
Query: 4234 KERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAM 4413
+ L ++I L+ +L+ + A R+ E + + + AE ++K+ +
Sbjct: 1795 LQHRLDEAEQI--ALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKEL 1852
Query: 4414 SQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAK 4593
+ + + + +L L + VD ++ ++ +R ++ + + +N F K HEL++A+
Sbjct: 1853 TYQTEEDKKNLLRLQDLVDKLQLKVK---AYKRQAEEAEEQANTNLSKFRKVQHELDEAE 1909
Query: 4594 RS---LEAELNDMRVQMEEL 4644
E+++N +R + ++
Sbjct: 1910 ERADIAESQVNKLRAKSRDI 1929
>gi|6754774|ref|NP_034986.1| myosin, heavy polypeptide 6, cardiac
muscle, alpha; myosin heavy chain, cardiac muscle, adult;
alpha myosin; alpha cardiac MHC; cardiomyopathy,
hypertrophic 1 [Mus musculus]
gi|3024204|sp|Q02566|MYH6_MOUSE Myosin heavy chain, cardiac muscle
alpha isoform (MyHC-alpha)
gi|2119306|pir||I49464 alpha cardiac myosin heavy chain - mouse
gi|191620|gb|AAA37160.1| alpha cardiac myosin heavy chain
gi|191624|gb|AAA37162.1| alpha cardiac myosin heavy chain
Length = 1938
Score = 1136 bits (2939), Expect = 0.0
Identities = 656/1898 (34%), Positives = 1060/1898 (55%), Gaps = 20/1898 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
R C+VPD E ++ + +V E + + VTI D V + NPPKFDKIEDM+
Sbjct: 34 RTECFVPDDKEEYVKAKVVSREGGKVTAE-TENGKTVTIKEDQVMQQNPPKFDKIEDMAM 92
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LT+L+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PP
Sbjct: 93 LTFLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPP 152
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAG-ATRNKSLNAAA 612
HIF+I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A R+K N A
Sbjct: 153 HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRSKKENPNA 212
Query: 613 QQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYIS 792
+ G LE Q++QANP LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++
Sbjct: 213 NK------------GTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLA 260
Query: 793 GANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYL-----LEGVDNYRFLVN 957
A+IE YLLEKSRV+ Q + ER++HIFYQIL + +K E L +Y F+
Sbjct: 261 SADIETYLLEKSRVIFQLKAERNYHIFYQIL----SNKKPELLDMLLVTNNPYDYAFVSQ 316
Query: 958 RGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAML 1137
+++ ++DD +E +T ++ ++ F +E + + ++ A++ GN++F Q+++ +QA
Sbjct: 317 GEVSVASIDDSEELLATDSAFDVLSFTAEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEP 376
Query: 1138 QDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERL 1317
K +L+GL +L K PR+KVG E+V K Q+ +Q +++ A+AK+ YE++
Sbjct: 377 DGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKSVYEKM 436
Query: 1318 FKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMF 1497
F W+VTRIN +L+ T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF
Sbjct: 437 FNWMVTRINATLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMF 495
Query: 1498 ILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQK 1677
+LEQEEY++EGIEW+FIDFG+DLQ IDLIEKPMG++++L+EEC+FPKA+D +F KL
Sbjct: 496 VLEQEEYKKEGIEWEFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKASDMTFKAKLYD 555
Query: 1678 TH-NKHPKFIVP---DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTD 1845
H K F P + ++HF++VHYAG VDY+ WL KN DPLNE VVGL Q S+
Sbjct: 556 NHLGKSNNFQKPRNVKGKQEAHFSLVHYAGTVDYNIMGWLEKNKDPLNETVVGLYQKSSL 615
Query: 1846 PFVAGIWKDAEFAGICAAEMNETAFGMRSRK--GMFRTVSQLHKEQLTKLMTTLRNTSPH 2019
+A + F+ +A+ ++ G +K F+TVS LH+E L KLMT L+ T PH
Sbjct: 616 KLMATL-----FSTYASADTGDSGKGKGGKKKGSSFQTVSALHRENLNKLMTNLKTTHPH 670
Query: 2020 FVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPD 2199
FVRCIIPN K G +++ LV+ QLRCNGVLEGIRICR+GFPNR+ + +FR RY IL P
Sbjct: 671 FVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPA 730
Query: 2200 VIPK-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNF 2376
IP+ FID ++ K++ +LDID N Y+ G +KVFF+ G+L LEE RD +L+ +I
Sbjct: 731 AIPEGQFIDSRKGAEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRI 790
Query: 2377 QAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDE 2556
QAQ RG L R + N A++ ++NW W +L+ K+KPLL+ T+ E
Sbjct: 791 QAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKE 850
Query: 2557 IRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRL 2736
+ +E K+ L K E +E E+K+ ++ E+ +Q Q+Q E +N + ++ +L
Sbjct: 851 MANMKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQL 910
Query: 2737 QTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDK 2916
+LE V +M +RL +RK + + +K
Sbjct: 911 IKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 970
Query: 2917 TNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLE 3096
+ + L E++ K+K +LE
Sbjct: 971 HATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKSKVKLE 1030
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
Q+ +LE L +E++ + +LE+ KRKL +L+ +++ + + +L +L K++ ++
Sbjct: 1031 QQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDIS 1090
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
Q ++ ++E A +QK++++ Q I+EL E++E ER AR K E R ++ +LE++
Sbjct: 1091 QQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEI-S 1149
Query: 3457 DVLDKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQI 3633
+ L++ AT +Q M++K E E +R +E+ E + K + V EL +QI
Sbjct: 1150 ERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQI 1209
Query: 3634 EQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESD 3813
+ ++ + +LEK++++ E D+ + + ++A+++K + E E + L E+
Sbjct: 1210 DNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQ 1269
Query: 3814 EHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKI 3993
Q + + E L R EE+E + + R + + K
Sbjct: 1270 RSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKN 1329
Query: 3994 ANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELR 4173
A + + + + L ++ EE +A L++ + A + R K E Q+ EEL
Sbjct: 1330 ALAHALQSSRHDCDLLREQYEEEMEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELE 1389
Query: 4174 KKNLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQK 4344
+ + + LQ E E + + ++K ++Q E+ED +++E A+ +K+Q+
Sbjct: 1390 EAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR 1449
Query: 4345 KFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQ 4524
F+ +AE + +++ + ++ +E R T + L N + EHLE R ++LQ+
Sbjct: 1450 NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQE 1509
Query: 4525 ELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQA 4704
E+ D + GKNVHELEK ++ LE E +++ +EE E +L+ E LR ++
Sbjct: 1510 EISDLTEQLGEGGKNVHELEKIRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQ 1569
Query: 4705 LKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQ 4884
+K+E +R ++ KD E E+ +R L+ + L+ L+ E R ++ A+ +KK+E + E+E
Sbjct: 1570 IKAEIERKLAEKDEEMEQAKRNHLRMVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEI 1629
Query: 4885 QLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQ 5064
QL ANR+ E + Q++ ++A A +D+ + +R+ ++AE E+
Sbjct: 1630 QLSQANRIASEAQKHLKNSQAHLKDTQLQLDDAVHANDDLKENIAIVERRNNLLQAELEE 1689
Query: 5065 LREANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSN 5235
LR E ++RK Q +K+++E+ + Q
Sbjct: 1690 LRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQTEVEEAVQE 1749
Query: 5236 CELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSR 5415
C A +K +KA + +L E+ + E K+++E++ +D + ++ E E A
Sbjct: 1750 CRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKG 1809
Query: 5416 ARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKEL 5595
+ Q+ LEA+V+ LE++L E + + + R+ E+R+ + T Q E++K+ + ++L
Sbjct: 1810 GKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLMRLQDL 1869
Query: 5596 LEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
++K LK + +RQ +EAE++ + +K R VQ E D+
Sbjct: 1870 VDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDE 1907
Score = 154 bits (388), Expect = 3e-35
Identities = 185/873 (21%), Positives = 374/873 (42%), Gaps = 17/873 (1%)
Frame = +1
Query: 3181 AELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTID 3360
AE E ++ E+ G+V++ + R +EL+ ++ V+L+Q++ +
Sbjct: 845 AETEKEMANMKEEFGRVKDALEKSEARRKELEEKM---------VSLLQEK--------N 887
Query: 3361 ELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT-MLQDLMSRKDEEVNATK 3537
+L+ ++ E++ N AE E QL K K + KV E T L+D +EE+NA
Sbjct: 888 DLQLQVQAEQDNLNDAE----ERCDQLIKNKIQLEAKVKEMTERLED-----EEEMNA-- 936
Query: 3538 RAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEI 3717
++ +K K + EL I+ + +++EK+++ + + ++ +E+
Sbjct: 937 ------------ELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEM 984
Query: 3718 ALLQASRADIDKKRK-IHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEE 3894
A L A + K++K + EAH + AE D+ TL + ++D L E+E
Sbjct: 985 AGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK-VNTLTKSKVKLEQQVDDLEGSLEQE 1043
Query: 3895 EHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLR 4074
+ +++R R+LE + + + E +
Sbjct: 1044 KKVRMDLERA----------------------------KRKLEGDLKLTQESIMDLENDK 1075
Query: 4075 AHLEKEIHAARQGAGEARRKAEE--SVNQQLEELRKKNLRDVEHLQKQLEESEVAKERIL 4248
LE+++ + K E+ ++ QL++ K+N +E L+++LE A+ ++
Sbjct: 1076 LQLEEKLKKKEFDISQQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVE 1135
Query: 4249 QSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELR 4428
+ + + +ELE+ S LE + + KK E++ + R +++A L +A + LR
Sbjct: 1136 KLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALR 1195
Query: 4429 DRETRVLSLLNE-VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLE 4605
+ ++ L E +D ++ ++ ++ + + EL D SN + K LEK R+LE
Sbjct: 1196 KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLE 1255
Query: 4606 AELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLL--- 4776
+ N+ RV++EE + +L R +L+ N E R + K+ + RG L
Sbjct: 1256 DQANEYRVKLEEAQRSLNDFTTQRAKLQTEN----GELARQLEEKEALISQLTRGKLSYT 1311
Query: 4777 KQIRDLENELENEKRGKSGAV----SHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXX 4944
+Q+ DL+ +LE E + K+ S R + + E+++E L+
Sbjct: 1312 QQMEDLKRQLEEEGKAKNALAHALQSSRHDCDLLREQYEEEMEAKAELQRVLSKANSEVA 1371
Query: 4945 XXXXEYQIEC----EEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXX 5112
+Y+ + EE +AK+ +A L++A+ AV A+ L + R Q
Sbjct: 1372 QWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKH-----RLQNE 1426
Query: 5113 XXXXXXXXXRAKGGGISSEEKRRLEAKI-AQXXXXXXXXQSNCELAIDKQRKAQVQLEQI 5289
R+ + ++K+R KI A+ QS E +Q + +
Sbjct: 1427 IEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE-------SSQKEARSL 1479
Query: 5290 TTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQ 5469
+T+L + +++ ++ +R N++ + +I++L + + +++ + Q
Sbjct: 1480 STELFKLKNAYEESLEHLETFKRENKNLQEEISDL-----TEQLGEGGKNVHELEKIRKQ 1534
Query: 5470 LNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEA 5649
L VE E L+ L + E E+ +A+ LE + +K + R+L E
Sbjct: 1535 LEVEKLE----------LQSALEEAEASLEHEEGKILRAQ--LEFNQIK-AEIERKLAEK 1581
Query: 5650 EDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
++EM + + H + LDA + E +
Sbjct: 1582 DEEMEQAKRNHLRMVDSLQTSLDAETRSRNEAL 1614
Score = 130 bits (326), Expect = 5e-28
Identities = 144/755 (19%), Positives = 314/755 (41%), Gaps = 44/755 (5%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + + D +E+ + +R +LE++ QE+ D+ ++ Q + D ++
Sbjct: 848 EKEMANMKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERC 907
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ L + +E L + + DE L + ++ E A ++
Sbjct: 908 DQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVE 967
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ K A N+ + L +E A LDE + A L KE
Sbjct: 968 KE---------------------KHATENKVKNLTEEM-AGLDE------IIAKLTKEKK 999
Query: 4099 AARQGAGEARR--KAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQ 4272
A ++ +A +AEE L + + K + V+ L+ LE+ + + + ++K+K++
Sbjct: 1000 ALQEAHQQALDDLQAEEDKVNTLTKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEG 1059
Query: 4273 EL---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETR 4443
+L ++S M+LEN + + K+ K+F+ ++ ++AL + + ++L++ + R
Sbjct: 1060 DLKLTQESIMDLENDKLQLEEKLKK-KEFDISQQNSKIEDEQALALQ--LQKKLKENQAR 1116
Query: 4444 VLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDM 4623
+ L E++ + + +++R L +EL++ ++ G + + EAE M
Sbjct: 1117 IEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKM 1176
Query: 4624 RVQME----------------------ELEDNLQIAEDARLRLEVTNQALKSESDRAISN 4737
R +E EL + + + + +LE K E D SN
Sbjct: 1177 RRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 1236
Query: 4738 KD--VEAEEKRRGLLKQIRDLENE----LENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
+ ++A+ + + + D NE LE +R + + R K++ + GEL +QLE
Sbjct: 1237 MEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEK 1296
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLR----EADRKFRAVEAEREQL 5067
L + + + + EE +AK +A L+ + D E E E
Sbjct: 1297 EALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSSRHDCDLLREQYEEEMEAK 1356
Query: 5068 REANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELA 5247
E L +A + + E K++L ++ + C
Sbjct: 1357 AELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSL 1416
Query: 5248 IDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQ 5427
+ + Q ++E + D+ + ++++ ++ ++K K E +S +S ++ +
Sbjct: 1417 EKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELES-SQKE 1475
Query: 5428 MAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKS 5607
+L ++ L++ + R + L++ ++D T+Q + + + +++ ++
Sbjct: 1476 ARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKIRKQL 1535
Query: 5608 NLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
++ L+ L+EAE + E K Q E + +
Sbjct: 1536 EVEKLELQSALEEAEASLEHEEGKILRAQLEFNQI 1570
Score = 99.4 bits (246), Expect = 1e-18
Identities = 130/575 (22%), Positives = 257/575 (44%), Gaps = 42/575 (7%)
Frame = +1
Query: 3046 DHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMG 3225
D +R + +AK +L +L + E+ + S LE+ K +L E+ED +
Sbjct: 1380 DAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNA 1439
Query: 3226 KVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELR-------EDMET 3384
L+ + D+ L +Y+E + + QK+ R + T + +L+ E +ET
Sbjct: 1440 AAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLET 1499
Query: 3385 -ERNARNKAE----MTRR-----EVVAQLEKVKGDV-LDKVDEATMLQDL---------- 3501
+R +N E +T + + V +LEK++ + ++K++ + L++
Sbjct: 1500 FKRENKNLQEEISDLTEQLGEGGKNVHELEKIRKQLEVEKLELQSALEEAEASLEHEEGK 1559
Query: 3502 MSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQ 3681
+ R E N K IE+ + ++E+ K R V+ L ++ + R++ + + +
Sbjct: 1560 ILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRMVDSLQTSLDAETRSRNEALRVKKK 1619
Query: 3682 ADQERADMAQEIALLQASR--ADIDKKRKIHEAHLMEIQANLAE----SDEHKRTLIDQL 3843
+ + +M EI L QA+R ++ K K +AHL + Q L + +D+ K +
Sbjct: 1620 MEGDLNEM--EIQLSQANRIASEAQKHLKNSQAHLKDTQLQLDDAVHANDDLKENIAIVE 1677
Query: 3844 ERS---RDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRAR 4014
R+ + EL+ L V E+ E + R+LA + IN+ +
Sbjct: 1678 RRNNLLQAELEELRAVVEQTERS-----RKLAEQELIETSERVQLLHSQNTSL--INQKK 1730
Query: 4015 QLEDEKNALLDEKEEA-EGLRAHLEKEIHAARQGAGEARR-KAEESVNQQLEELRKKNLR 4188
++E + L E EEA + R EK A A A K E+ + LE ++K +
Sbjct: 1731 KMESDLTQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQ 1790
Query: 4189 DVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAE 4368
++ LQ +L+E+E + L+ KK Q+LE ELEN + E QK+ AE
Sbjct: 1791 TIKDLQHRLDEAE---QIALKGGKKQLQKLEARVRELEN------ELEAEQKR----NAE 1837
Query: 4369 ERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISN 4548
++K+ ++ + + + ++ L + VD ++ ++ +R ++ + + +N
Sbjct: 1838 SVKGMRKSERRIKELTYQTEEDKKNLMRLQDLVDKLQLKVK---AYKRQAEEAEEQANTN 1894
Query: 4549 KDDFGKNVHELEKAKRS---LEAELNDMRVQMEEL 4644
F K HEL++A+ E+++N +R + ++
Sbjct: 1895 LSKFRKVQHELDEAEERADIAESQVNKLRAKSRDI 1929
>gi|49523259|gb|AAH75407.1| Unknown (protein for MGC:89159) [Xenopus
tropicalis]
Length = 1935
Score = 1136 bits (2938), Expect = 0.0
Identities = 660/1895 (34%), Positives = 1067/1895 (55%), Gaps = 17/1895 (0%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
R +V D E ++ G+++ + + V+ + + VT+ D + NPPKFDKIEDM+
Sbjct: 35 RTSMFVVDTKESYVKGTLQSKEGGKATVK-TEAGQTVTVKDDQIFPMNPPKFDKIEDMAM 93
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
+T+LNE SVL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PP
Sbjct: 94 MTHLNEPSVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVNAYRGKKRQEAPP 153
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIF+I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A A K
Sbjct: 154 HIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAAAPDKK------- 206
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
K +V G LE Q++QANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++
Sbjct: 207 -----KEEVAKTKGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLAS 261
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRF-LVNRG-IT 969
A+IE YLLEKSRV Q + ERS+HIFYQI+ E E LL + Y F V++G I+
Sbjct: 262 ADIETYLLEKSRVTFQLKAERSYHIFYQIMSN-KKPELIEMLLITTNPYDFPFVSQGEIS 320
Query: 970 LPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDR 1149
+ ++DD +E +T +++ I+GF DE SI ++ AV+ GN+ F Q+++ +QA
Sbjct: 321 VASIDDTEELMATDSAIDILGFNADEKVSIYKLTGAVMHYGNMRFKQKQREEQAEPDGTE 380
Query: 1150 VIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWL 1329
V K +L+ L +L KA PR+KVG E+V K Q +Q +V A+ KA YE++F W+
Sbjct: 381 VADKAAYLMCLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNSVGALGKAVYEKMFLWM 440
Query: 1330 VTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQ 1509
VTRIN+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQ
Sbjct: 441 VTRINEMLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQ 499
Query: 1510 EEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-N 1686
EEY++EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H
Sbjct: 500 EEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLG 559
Query: 1687 KHPKFIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVA 1857
K F P ++++HF++VHYAG VDY+ WL KN DPLN+ V+GL Q S+ +A
Sbjct: 560 KSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNISGWLEKNKDPLNDTVIGLFQKSSMKTLA 619
Query: 1858 GIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCII 2037
+ F+ A+E G + + F+TVS L +E L KLM+ LR T PHFVRCII
Sbjct: 620 YL-----FSSYAASEAEGAKKGGKKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCII 674
Query: 2038 PNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-N 2214
PN K G + LVL QLRCNGVLEGIRICR+GFP+R+ + +F+ RY+IL IP+
Sbjct: 675 PNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKILNASAIPEGQ 734
Query: 2215 FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRG 2394
FID K++ K++ ++D+D YR G +KVFF+ G+L LEE RD +L +I QA CRG
Sbjct: 735 FIDSKKASEKLLGSIDVDHTQYRFGHTKVFFKAGLLGTLEEMRDDRLAHVITRTQAMCRG 794
Query: 2395 FLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDD 2574
+L R + N +++ +++W W +L+ K+KPLL+ ++ E++ +
Sbjct: 795 YLMRVEFKKMMERREAVFTIQYNIRSFMNVKHWPWMKLYFKIKPLLKSAESEKEMQNMKE 854
Query: 2575 ELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQE 2754
E TKE L K E +E E+K+ +V+ E+ +Q Q+Q ESEN + ++ +L +
Sbjct: 855 EFEKTKELLAKSEAKRKELEEKMVKVLQEKNDLQLQVQSESENLTDAEERCDQLIKSKIQ 914
Query: 2755 LEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQX 2934
LE + ++ +RL +RK + + +K +
Sbjct: 915 LEAKMKELNERLEDEEESNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 974
Query: 2935 XXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHEL 3114
+ L E++ KAK +LE Q+ +L
Sbjct: 975 VKNLTEEMAVLDETIVKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKAKLEQQVDDL 1034
Query: 3115 EQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRY 3294
E L +E++ + +LE+ KRKL +L+ +++ + + ++L+ +L K++ E+ ++
Sbjct: 1035 EGSLEQEKKLRMDLERSKRKLEGDLKLAQETIMDLENDRQQLDEKLKKKEFEMSQYASKI 1094
Query: 3295 DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKV 3474
++E A +QK+++++Q I+EL E++E ER AR KAE R ++ +LE++ + L++
Sbjct: 1095 EDEQALGAQLQKKIKELQARIEELEEEIEAERAARAKAEKQRSDLSRELEEI-SERLEEA 1153
Query: 3475 DEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQ 3651
AT Q M++K E E +R +E+ E + K + V EL +QI+ ++
Sbjct: 1154 GGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKQADSVAELGEQIDNLQRV 1213
Query: 3652 RSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTL 3831
+ +LEK++++ E D+A + L ++A+ +K + E L E++ + +EH+R +
Sbjct: 1214 KQKLEKEKSELKMEIDDLASNMENLSKAKANFEKICRTLEDQLSELK---TKDEEHQRQI 1270
Query: 3832 ID---QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANI 4002
D Q R + E R EE + + + R + K A
Sbjct: 1271 NDLTAQRARLQTENGEYARQLEERDSLISQLSRGKQAFTQQIEELKRQLEEEIKAKNALA 1330
Query: 4003 NRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN 4182
+ + + + L ++ EE + + L++ + A + R K E Q+ EEL
Sbjct: 1331 HGLQSARHDCDLLREQYEEEQEAKGELQRSLSKANGEVAQWRTKYETDAIQRTEELEDAK 1390
Query: 4183 LRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFE 4353
+ + LQ+ E E + + ++K+++Q E+ED +++E ++ +K+QK F+
Sbjct: 1391 KKLAQRLQEAEEHIEAVNSKCASLEKTKQRLQNEVEDLMVDVERSNSACAALDKKQKNFD 1450
Query: 4354 SQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQ 4533
+AE + +++ + +A +E R T + + N + +HLE + R ++LQQE+
Sbjct: 1451 KILAEWKQKFEESQAELEASQKESRSLSTELFKMKNAYEESLDHLETTKRENKNLQQEIS 1510
Query: 4534 DSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKS 4713
D + K +HE+EKAK+ +E E +++ +EE E +L+ E LR+++ +KS
Sbjct: 1511 DLTEQVSEVSKTLHEVEKAKKIIEQEKTEIQSALEEAEASLEHEEGKILRIQLELNQVKS 1570
Query: 4714 ESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLE 4893
E DR I+ KD E ++ +R ++ + +++ L+ E R ++ A+ +KK+E + E+E QL
Sbjct: 1571 EIDRKIAEKDEEIDQLKRNHVRVVESMQSTLDAEIRSRNDALRLKKKMEGDLNEMEIQLS 1630
Query: 4894 VANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLRE 5073
ANR E + QI +++ +A+ED+ L +R+ ++AE E++R
Sbjct: 1631 HANRQASESQKQLRNVQGLLKDVQIHLDDSLRAQEDLKEQLAMVERRANLMQAEIEEMRA 1690
Query: 5074 ANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCEL 5244
A E ++RK Q K+++E I Q
Sbjct: 1691 ALEQTERSRKVAEQELLDASERVQLLHSQNTSLINTKKKMETDITQLQTEVEEAIQEARN 1750
Query: 5245 AIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARA 5424
A +K +KA + +L E+ + E K++L+++ +D + ++ E E A +
Sbjct: 1751 AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLDQTVKDLQHRLDEAEQLAMKGGKK 1810
Query: 5425 QMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEK 5604
Q+ LEA+V+ LE++++VE + T A + R+ E+R+ + + Q E++K+ + ++L++K
Sbjct: 1811 QIQKLEARVRELENEVDVEQKRSTEAIKGVRKYERRVKELSYQSEEDKKNILRLQDLVDK 1870
Query: 5605 SNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+K + +RQ +E E++ + TK+R +Q E ++
Sbjct: 1871 LQMKVKAYKRQTEEIEEQSNINLTKYRKIQHELEE 1905
Score = 154 bits (388), Expect = 3e-35
Identities = 180/928 (19%), Positives = 389/928 (41%), Gaps = 42/928 (4%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + + ++ L + + ELE+ K+L E D + + +E + EE +
Sbjct: 847 KEMQNMKEEFEKTKELLAKSEAKRKELEEKMVKVLQEKNDLQLQVQSESENLTDAEERCD 906
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE +N L K+ R ++ EL++D++ E
Sbjct: 907 QLIKSKIQLEAKMKELNERLEDEEESNAELTAKK-RKLEDECSELKKDIDD-------LE 958
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E +L + + + +E A + A +Q ++ +
Sbjct: 959 LTLAKVEKEKHATENKVKNLTEEMAVLDETIVKLTKEKKALQEAHQQTLDDLQAEEDKVN 1018
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK 3753
+ + KAK +QV++L +EQ KK R LE+ + + + + + I L+ R +D+
Sbjct: 1019 TLTKAKAKLEQQVDDLEGSLEQEKKLRMDLERSKRKLEGDLKLAQETIMDLENDRQQLDE 1078
Query: 3754 KRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLAT 3933
K K E + + + + E ++ L QL++ EL R+ E EE A R
Sbjct: 1079 KLKKKEFEMSQYASKI----EDEQALGAQLQKKIKELQ--ARIEELEEEIEAERAARAKA 1132
Query: 3934 AXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQG 4113
RL+ A + Q+E +++K EAE
Sbjct: 1133 EKQRSDLSRELEEISERLEEAGGATSAQIE------MNKKREAE---------------- 1170
Query: 4114 AGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELED 4284
+ RR EE+ Q LRKK V L +Q++ + K+++ + K +++ E++D
Sbjct: 1171 FQKMRRDLEEATLQHEATAAALRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDD 1230
Query: 4285 SSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNE 4464
+ +EN+ + + EK + E Q++E + ++ +++ D + L E
Sbjct: 1231 LASNMENLSKAKANFEKICRTLEDQLSELKTKDEE-------HQRQINDLTAQRARLQTE 1283
Query: 4465 VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEEL 4644
LEE D + L + Q ++ + + E KAK +L L R + L
Sbjct: 1284 NGEYARQLEERDSLISQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHGLQSARHDCDLL 1343
Query: 4645 EDNLQIAEDARLRL---------EVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLE 4797
+ + ++A+ L EV K E+D AI + E E+ ++ L +++++ E
Sbjct: 1344 REQYEEEQEAKGELQRSLSKANGEVAQWRTKYETD-AIQRTE-ELEDAKKKLAQRLQEAE 1401
Query: 4798 NELENEKRGKSGAVSHRKKIENQIGELEQQLEVAN-------RLKEEYXXXXXXXXXXXX 4956
+E + +++++N++ +L +E +N + ++ +
Sbjct: 1402 EHIEAVNSKCASLEKTKQRLQNEVEDLMVDVERSNSACAALDKKQKNFDKILAEWKQKFE 1461
Query: 4957 EYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQA---RKQXXXXXXX 5127
E Q E E +++ ++ L + + E + N+ L Q +
Sbjct: 1462 ESQAELEASQKESRSLSTELFKMKNAYEESLDHLETTKRENKNLQQEISDLTEQVSEVSK 1521
Query: 5128 XXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSM 5307
K I +EK +++ + + +++ E K + Q++L Q+ ++
Sbjct: 1522 TLHEVEKAKKIIEQEKTEIQSALEE-------AEASLEHEEGKILRIQLELNQVKSE--- 1571
Query: 5308 ERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAAL------EAKVQYLEDQ 5469
+++K + + +++ R++ + ++S + R++ AL E + +E Q
Sbjct: 1572 ---IDRKIAEKDEEIDQLKRNHVRVVESMQSTLDAEIRSRNDALRLKKKMEGDLNEMEIQ 1628
Query: 5470 LNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEA 5649
L+ ++ + + + R ++ L D +D RA E KE L + ++ +++E
Sbjct: 1629 LSHANRQASESQKQLRNVQGLLKDVQIHLDDSLRAQEDLKEQLAMVERRANLMQAEIEEM 1688
Query: 5650 EDEMSRERTKHRNVQREADDLLDANEQL 5733
+ + + ++E LLDA+E++
Sbjct: 1689 RAALEQTERSRKVAEQE---LLDASERV 1713
Score = 125 bits (315), Expect = 9e-27
Identities = 137/756 (18%), Positives = 317/756 (41%), Gaps = 45/756 (5%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ + E+ + + + + +R +LE++ + QE+ D+ ++ + D ++
Sbjct: 846 EKEMQNMKEEFEKTKELLAKSEAKRKELEEKMVKVLQEKNDLQLQVQSESENLTDAEERC 905
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ L + +E L + + DE L + ++ E A ++
Sbjct: 906 DQLIKSKIQLEAKMKELNERLEDEEESNAELTAKKRKLEDECSELKKDIDDLELTLAKVE 965
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ T K+ N+ + DE L ++++A +
Sbjct: 966 KE---------------KHATENKVKNLTEEMAVLDETIVKLTKEKKA----------LQ 1000
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
A Q + + E+ VN L + + K + V+ L+ LE+ + + + +SK+K++ +L
Sbjct: 1001 EAHQQTLDDLQAEEDKVNT-LTKAKAKLEQQVDDLEGSLEQEKKLRMDLERSKRKLEGDL 1059
Query: 4279 ---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL 4449
+++ M+LEN R D + ++K+FE ++ ++AL + +++++ + R+
Sbjct: 1060 KLAQETIMDLENDR-QQLDEKLKKKEFEMSQYASKIEDEQAL--GAQLQKKIKELQARIE 1116
Query: 4450 SLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRV 4629
L E++ + ++++ R L +EL++ ++ G + + EAE MR
Sbjct: 1117 ELEEEIEAERAARAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR 1176
Query: 4630 QME----------------------ELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
+E EL + + + + +LE LK E D SN +
Sbjct: 1177 DLEEATLQHEATAAALRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNME 1236
Query: 4744 VEAEEKR------RGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANR 4905
++ K R L Q+ +L+ + E +R + + R +++ + GE +QLE +
Sbjct: 1237 NLSKAKANFEKICRTLEDQLSELKTKDEEHQRQINDLTAQRARLQTENGEYARQLEERDS 1296
Query: 4906 LKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA----DRKFRAVEAEREQLRE 5073
L + E + + EE +AK +A L+ A D E E+E E
Sbjct: 1297 LISQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHGLQSARHDCDLLREQYEEEQEAKGE 1356
Query: 5074 ANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAID 5253
L +A + + + K++L ++ + S C
Sbjct: 1357 LQRSLSKANGEVAQWRTKYETDAIQRTEELEDAKKKLAQRLQEAEEHIEAVNSKCASLEK 1416
Query: 5254 KQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMA 5433
+++ Q ++E + D+ + + ++++ ++ ++K K E ++ ++ ++ +
Sbjct: 1417 TKQRLQNEVEDLMVDVERSNSACAALDKKQKNFDKILAEWKQKFEESQAELEA-SQKESR 1475
Query: 5434 ALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRA---NEQAKELLEK 5604
+L ++ +++ R + L++ ++D T+Q + + E+AK+++E+
Sbjct: 1476 SLSTELFKMKNAYEESLDHLETTKRENKNLQQEISDLTEQVSEVSKTLHEVEKAKKIIEQ 1535
Query: 5605 SNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ ++ L+EAE + E K +Q E + +
Sbjct: 1536 ---EKTEIQSALEEAEASLEHEEGKILRIQLELNQV 1568
Score = 78.6 bits (192), Expect = 2e-12
Identities = 113/521 (21%), Positives = 204/521 (38%), Gaps = 18/521 (3%)
Frame = +1
Query: 4234 KERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAM 4413
K + L + ++E+++ E E + SE ++K+ E +M + L +
Sbjct: 835 KIKPLLKSAESEKEMQNMKEEFEKTKELLAKSEAKRKELEEKMVKVLQEKNDLQLQVQSE 894
Query: 4414 SQELRDRETRVLSLLN----------EVDIMKEHLEESDRVRRSLQQELQDSISNKDDFG 4563
S+ L D E R L+ E++ E EES+ + +++L+D S +
Sbjct: 895 SENLTDAEERCDQLIKSKIQLEAKMKELNERLEDEEESNAELTAKKRKLEDECS---ELK 951
Query: 4564 KNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
K++ +LE +E E + +++ L + + + ++ ++L +AL+ + + D
Sbjct: 952 KDIDDLELTLAKVEKEKHATENKVKNLTEEMAVLDETIVKLTKEKKALQEAHQQTLD--D 1009
Query: 4744 VEAEEKRRGLL--------KQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
++AEE + L +Q+ DLE LE EK+ R +E +LE L++A
Sbjct: 1010 LQAEEDKVNTLTKAKAKLEQQVDDLEGSLEQEKK-------LRMDLERSKRKLEGDLKLA 1062
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREAN 5079
+ + + E + ED AL + +K + ++A E+L E
Sbjct: 1063 QETIMDLENDRQQLDEKLKKKEFEMSQYASKIEDEQALGAQLQKKIKELQARIEELEEEI 1122
Query: 5080 EGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQ 5259
E AR AK S+ R LE
Sbjct: 1123 EAERAAR--------------AKAEKQRSDLSRELE------------------------ 1144
Query: 5260 RKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAAL 5439
+ +LE+ S + +N+K EAE Q + R +LE A + A AAL
Sbjct: 1145 -EISERLEEAGGATSAQIEMNKKREAEFQKMRR----------DLEE-ATLQHEATAAAL 1192
Query: 5440 EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKN 5619
K D + G++ R ++LEK ++ + +D E L K+
Sbjct: 1193 RKK---QADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMEN----LSKAKANF 1245
Query: 5620 RNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
+ R L ED++S +TK QR+ +DL +L E
Sbjct: 1246 EKICRTL---EDQLSELKTKDEEHQRQINDLTAQRARLQTE 1283
>gi|27529913|dbj|BAA96036.2| KIAA1512 protein [Homo sapiens]
Length = 2010
Score = 1135 bits (2937), Expect = 0.0
Identities = 673/1897 (35%), Positives = 1053/1897 (55%), Gaps = 16/1897 (0%)
Frame = +1
Query: 67 WAQRKLCWVPDQNEGFLIGSIKRE-TNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIE 243
W +K WVPD+ + ++ +K E T V VE D + + + ++Q NPP+FD +E
Sbjct: 98 WDGKKRVWVPDEQDAYVEAEVKSEATGGRVTVETKD-QKVLMVREAELQPMNPPRFDLLE 156
Query: 244 DMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRH 423
DM+ +T+LNEASVLHNL+ RY +IYTYSGLFCV INPYK LP+Y+ ++ +KGK+R
Sbjct: 157 DMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCVTINPYKWLPVYTASVVAAYKGKRRS 216
Query: 424 EMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLN 603
+ PPHI+A+AD AY ML+ R++QS+L TGESGAGKT NTK+VIQY A VA
Sbjct: 217 DSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAGKTVNTKRVIQYFAIVAALGDGPGKK 276
Query: 604 AAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSG 783
A Q + K G LE Q+++ANP +EAFGN+KT++NDNSSRFGKFIRI+F SG
Sbjct: 277 A---QFLATKTG-----GTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPSG 328
Query: 784 YISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLE-GVDNYRFLVNR 960
++ A+I+ YLLEKSRV+ Q ERS+H++YQIL G + + LL +Y F
Sbjct: 329 KLASADIDSYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQDMLLLSMNPYDYHFCSQG 388
Query: 961 GITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQ 1140
IT+ N++D +E +T ++M I+GF+ DE + ++V A+L GN++F Q+++ +QA
Sbjct: 389 VITVDNMNDGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNMKFKQKQREEQAEAD 448
Query: 1141 DDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLF 1320
K +L+G+ +L K L PR++VG E+V K Q+ EQ FAV A+AKA+Y+RLF
Sbjct: 449 GTESADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQVVFAVGALAKATYDRLF 508
Query: 1321 KWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFI 1500
+WLV+RIN++LD T FIG+LDIAGFEIF+ NSFEQ+CIN+TNEKLQQ FN MF+
Sbjct: 509 RWLVSRINQTLD-TKLPRQFFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNQHMFV 567
Query: 1501 LEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKT 1680
LEQEEY+REGI+W FIDFGLDLQP IDLIEKP+G+L++L+EEC+FPKA+D SF KL
Sbjct: 568 LEQEEYKREGIDWVFIDFGLDLQPCIDLIEKPLGILSILEEECMFPKASDASFRAKLYDN 627
Query: 1681 H-NKHPKFIV--PDMRSK--SHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTD 1845
H K P F PD + K +HF VVHYAG V YS WL KN DPLNE VV + Q S +
Sbjct: 628 HAGKSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNKDPLNETVVPIFQKSQN 687
Query: 1846 PFVAGIWKDAEFAGICAAEMNETAFGMRSRK-GMFRTVSQLHKEQLTKLMTTLRNTSPHF 2022
+A ++++ +AG C+ E ++ + +K F+TVSQLHKE L KLMT LR T PHF
Sbjct: 688 RLLATLYEN--YAGSCSTEPPKSGVKEKRKKAASFQTVSQLHKENLNKLMTNLRATQPHF 745
Query: 2023 VRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDV 2202
VRCI+PN K G +++ LVL QLRCNGVLEGIRICRQGFPNR+ + +FR RY IL P
Sbjct: 746 VRCIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLLYTDFRQRYRILNPSA 805
Query: 2203 IPKN-FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQ 2379
IP + F+D +++ K++ +LD+D Y+ G +KVFF+ G+L LEE RD +L ++ Q
Sbjct: 806 IPDDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVFFKAGLLGVLEELRDQRLAKVLTLLQ 865
Query: 2380 AQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEI 2559
A+ RG L R Y N A+ ++NW W +LF K+KPLL+ + ++E+
Sbjct: 866 ARSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAVKNWSWMKLFFKMKPLLRSAQAEEEL 925
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
A ELR + L E +E E+ + E+ + QLQ E +N A+ ++ L
Sbjct: 926 AALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHLLI 985
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
+LE V ++ +RL RRK + + +K
Sbjct: 986 KSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLELTLAKAEKEKQ 1045
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLEN 3099
+ ++ L E+R KAK RLE
Sbjct: 1046 ATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQ 1105
Query: 3100 QLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQH 3279
Q+ +LE L +E++ + + E+ KRKL +L+ +++ +A+ ++L +L K+D EL
Sbjct: 1106 QVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQ 1165
Query: 3280 QLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGD 3459
R ++E MQK+++++Q +EL E++E ER AR + E R E +LE++
Sbjct: 1166 LSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSER 1225
Query: 3460 VLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQ 3639
+ + + ++ +++ E+ +R +E+ E + + K + EL +Q++
Sbjct: 1226 LEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDS 1285
Query: 3640 HKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEH 3819
++ R +LEK++++ E D+A + L ++A +K + +E L E + + E
Sbjct: 1286 LQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQ 1345
Query: 3820 KRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIAN 3999
Q R + E L+R+ EE+E + + R A A ++ K A
Sbjct: 1346 LADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSAL 1405
Query: 4000 INRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKK 4179
+ + L + + L ++ EE +A L++ + A + R K E Q+ EEL +
Sbjct: 1406 AHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEA 1465
Query: 4180 NLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKF 4350
+ LQ+ E E A + + ++K ++Q E ED ++ELE ++ +K+Q+
Sbjct: 1466 KKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHL 1525
Query: 4351 ESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQEL 4530
E + E R ++ + +A +E R T + L + + E LE R ++LQ+E+
Sbjct: 1526 ERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEI 1585
Query: 4531 QDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALK 4710
D GK++ ELEK K++LE E ++++ +EE E L++ E LR+++ +K
Sbjct: 1586 SDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVK 1645
Query: 4711 SESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
+E DR ++ KD E RR + + L+ L+ E R ++ A+ +KK+E + +LE QL
Sbjct: 1646 AEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQL 1705
Query: 4891 EVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLR 5070
A R E E Q +E ++ ++ + +R+ + AE E+LR
Sbjct: 1706 GHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELR 1765
Query: 5071 EANEGLMQARK----QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNC 5238
A E ++R+ + ++ G+ + +K++LEA +AQ
Sbjct: 1766 AALEQGERSRRLAEQELLEATERLNLLHSQNTGLLN-QKKKLEADLAQLSGEVEEAAQER 1824
Query: 5239 ELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRA 5418
A +K +KA + +L E+ + E K++LE++ R+ +A++ E E A
Sbjct: 1825 REAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGG 1884
Query: 5419 RAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELL 5598
+ Q+ LEAKV+ LE +L+ E ++ A + R+ E+R+ + Q E++++ + ++L+
Sbjct: 1885 KKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLV 1944
Query: 5599 EKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+K K ++ +RQ +EAE + + K+R Q E DD
Sbjct: 1945 DKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDD 1981
Score = 104 bits (260), Expect = 2e-20
Identities = 159/731 (21%), Positives = 299/731 (40%), Gaps = 40/731 (5%)
Frame = +1
Query: 3679 QADQERADMAQEIALLQASRADIDKKRK-IHEAHL----------MEIQA---NLAESDE 3816
QA++E A + E+ L+ + A + KR+ + E H+ +++QA NLA+++E
Sbjct: 920 QAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEE 979
Query: 3817 HKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIA 3996
LI + ++ L+ E+EE A++ R
Sbjct: 980 RCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAAR------------------------ 1015
Query: 3997 NINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAAR---QGAGEARRKAEESVNQQLEE 4167
R+LEDE L + ++ E A EKE A + E +ESV + +E
Sbjct: 1016 ----RRKLEDECTELKKDIDDLELTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKE 1071
Query: 4168 LRKKNLRDVEHLQKQLEESEVAKERI---LQSKKKIQQELEDSSMELENVRASHRDSEKR 4338
KK L++ Q+ L + + ++R+ ++K +++Q++ED LE + D+E+
Sbjct: 1072 --KKALQEAH--QQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERA 1127
Query: 4339 QKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSL 4518
++K E + + +V A D+ + ++L+ +++ E+ + +E+ + +
Sbjct: 1128 KRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDS-------ELSQLSLRVEDEQLLGAQM 1180
Query: 4519 QQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTN 4698
Q K + EL+ LE EL R +E Q AE AR E++
Sbjct: 1181 Q--------------KKIKELQARAEELEEELEAERAARARVEK--QRAEAARELEELSE 1224
Query: 4699 QALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGEL 4878
+ ++ A + E G L+ R+LE E R ++ + R+K EL
Sbjct: 1225 RLEEAGGASAGQREGCRKREAELGRLR--RELE---EAALRHEATVAALRRKQAEGAAEL 1279
Query: 4879 EQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAER 5058
+Q++ R++++ E ++E ++ E + A++ R E
Sbjct: 1280 GEQVDSLQRVRQKLEKEKS-------ELRMEVDDLAANVETLTRAKASAEKLCRTYE--- 1329
Query: 5059 EQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISS--EEKRRLEAKIAQXXXXXXXXQS 5232
+QL EA + + ++Q + + G +S EEK L +++++
Sbjct: 1330 DQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLE 1389
Query: 5233 NCELAIDKQRKAQVQLEQITTDLSMERTL---NQKTEAEKQS-LERSNRDYKAKITELES 5400
++++ KA+ L L + L + EAE Q+ L+R A++ + S
Sbjct: 1390 ELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRS 1449
Query: 5401 GAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANE 5580
++ A + LE + L +L + AAN LEK + ED E
Sbjct: 1450 KYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELE 1509
Query: 5581 QAKELLEKSNLKNRNLRRQLDE---AEDEMSRE-----------RTKHRNVQREADDLLD 5718
+A + K R+L R L+E E+EM RE T+ ++ ++ L+
Sbjct: 1510 RATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALE 1569
Query: 5719 ANEQLTRELMN 5751
A E L RE N
Sbjct: 1570 ALETLKRENKN 1580
>gi|3041706|sp|P13533|MYH6_HUMAN Myosin heavy chain, cardiac muscle
alpha isoform (MyHC-alpha)
Length = 1939
Score = 1135 bits (2937), Expect = 0.0
Identities = 658/1898 (34%), Positives = 1057/1898 (55%), Gaps = 20/1898 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
R C+VPD E F+ I +V+ E + + VT+ D V + NPPKFDKI+DM+
Sbjct: 34 RTECFVPDDKEEFVKAKILSREGGKVIAE-TENGKTVTVKEDQVLQQNPPKFDKIQDMAM 92
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LT+L+E +VL NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PP
Sbjct: 93 LTFLHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPP 152
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAG-ATRNKSLNAAA 612
HIF+I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A R K NA A
Sbjct: 153 HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNANA 212
Query: 613 QQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYIS 792
+ G LE Q++QANP LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++
Sbjct: 213 NK------------GTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLA 260
Query: 793 GANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYL-----LEGVDNYRFLVN 957
A+IE YLLEKSRV+ Q + ER++HIFYQIL + +K E L +Y F+
Sbjct: 261 SADIETYLLEKSRVIFQLKAERNYHIFYQIL----SNKKPELLDMLLVTNNPYDYAFVSQ 316
Query: 958 RGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAML 1137
+++ ++DD +E +T ++ ++GF +E + + ++ A++ GN++F Q+++ +QA
Sbjct: 317 GEVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEP 376
Query: 1138 QDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERL 1317
K +L+GL +L K PR+KVG E+V K Q+ +Q +++ A+AKA YE++
Sbjct: 377 DGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKM 436
Query: 1318 FKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMF 1497
F W+VTRIN +L+ T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF
Sbjct: 437 FNWMVTRINATLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMF 495
Query: 1498 ILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQK 1677
+LEQEEY++EGIEW FIDFG+DLQ IDLIEKPMG++++L+EEC+FPKA D +F KL
Sbjct: 496 VLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLYD 555
Query: 1678 TH-NKHPKFIVP---DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTD 1845
H K F P + ++HF+++HYAG VDY+ WL KN DPLNE VV L Q S+
Sbjct: 556 NHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSL 615
Query: 1846 PFVAGIWKDAEFAGICAAEMNET--AFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPH 2019
+A + F+ A+ ++ + G + + F+TVS LH+E L KLMT LR T PH
Sbjct: 616 KLMATL-----FSSYATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPH 670
Query: 2020 FVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPD 2199
FVRCIIPN K G +++ LV+ QLRCNGVLEGIRICR+GFPNR+ + +FR RY IL P
Sbjct: 671 FVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPV 730
Query: 2200 VIPK-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNF 2376
IP+ FID ++ K++++LDID N Y+ G +KVFF+ G+L LEE RD +L+ +I
Sbjct: 731 AIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRM 790
Query: 2377 QAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDE 2556
QAQ RG L R + N A++ ++NW W +L+ K+KPLL+ T+ E
Sbjct: 791 QAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKE 850
Query: 2557 IRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRL 2736
+ +E KE L K E +E E+K+ ++ E+ +Q Q+Q E +N + ++ +L
Sbjct: 851 MATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQL 910
Query: 2737 QTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDK 2916
+LE V +M +RL +RK + + +K
Sbjct: 911 IKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 970
Query: 2917 TNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLE 3096
+ + L E++ K+K +LE
Sbjct: 971 HATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLE 1030
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
Q+ +LE L +E++ + +LE+ KRKL +L+ +++ + + +L +L K++ ++
Sbjct: 1031 QQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDIN 1090
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
Q ++ ++E A +QK++++ Q I+EL E++E ER AR K E R ++ +LE++
Sbjct: 1091 QQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEI-S 1149
Query: 3457 DVLDKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQI 3633
+ L++ AT +Q M++K E E +R +E+ E + K + V EL +QI
Sbjct: 1150 ERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQI 1209
Query: 3634 EQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESD 3813
+ ++ + +LEK++++ E D+ + + ++A+++K + E E + L E+
Sbjct: 1210 DNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQ 1269
Query: 3814 EHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKI 3993
Q + + E L R EE+E + + R + + K
Sbjct: 1270 RSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKN 1329
Query: 3994 ANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELR 4173
A + + + + L ++ EE +A L++ + A + R K E Q+ EEL
Sbjct: 1330 ALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELE 1389
Query: 4174 KKNLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQK 4344
+ + + LQ E E + + ++K ++Q E+ED +++E A+ +K+Q+
Sbjct: 1390 EAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR 1449
Query: 4345 KFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQ 4524
F+ +AE + +++ + ++ +E R T + L N + EHLE R ++LQ+
Sbjct: 1450 NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQE 1509
Query: 4525 ELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQA 4704
E+ D + GKNVHELEK ++ LE E +++ +EE E +L+ E LR ++
Sbjct: 1510 EISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQ 1569
Query: 4705 LKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQ 4884
+K+E +R ++ KD E E+ +R + + L+ L+ E R ++ + +KK+E + E+E
Sbjct: 1570 IKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEI 1629
Query: 4885 QLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQ 5064
QL ANR+ E + QI+ ++A +A +D+ + +R+ ++AE E+
Sbjct: 1630 QLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEE 1689
Query: 5065 LREANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSN 5235
LR E ++RK Q +K+++EA + Q
Sbjct: 1690 LRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMEADLTQLQSEVEEAVQE 1749
Query: 5236 CELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSR 5415
C A +K +KA + +L E+ + E K+++E++ +D + ++ E E A
Sbjct: 1750 CRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKG 1809
Query: 5416 ARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKEL 5595
+ Q+ LEA+V+ LE +L E + + + R+ E+R+ + T Q E++K+ + ++L
Sbjct: 1810 GKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDL 1869
Query: 5596 LEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
++K LK + +RQ +EAE++ + +K R VQ E D+
Sbjct: 1870 VDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDE 1907
Score = 152 bits (385), Expect = 7e-35
Identities = 160/820 (19%), Positives = 355/820 (42%), Gaps = 24/820 (2%)
Frame = +1
Query: 3361 ELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKR 3540
E ++M T + + + T + A+ ++++ ++ + E LQ + + + +N +
Sbjct: 846 ETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEE 905
Query: 3541 AIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIA 3720
+Q+ + K + +V+E+++++E ++ ++L ++ + + E +++ ++I
Sbjct: 906 RCDQLI--------KNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDID 957
Query: 3721 LLQASRADIDKKRKIHEAHLMEIQANLAESDE-------HKRTLIDQLERSRDELDHLNR 3879
L+ + A ++K++ E + + +A DE K+ L + +++ D+L +
Sbjct: 958 DLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDL----Q 1013
Query: 3880 VREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEE 4059
V E++ ++ + + +L ++++ R+LE + + +
Sbjct: 1014 VEEDKVNSLSKSKVKLEQQVDDLEGSLEQEK---KVRMDLERAKRKLEGDLKLTQESIMD 1070
Query: 4060 AEGLRAHLEKEIHAARQGAGEARRKAEE--SVNQQLEELRKKNLRDVEHLQKQLEESEVA 4233
E + LE+++ + K E+ ++ QL++ K+N +E L+++LE A
Sbjct: 1071 LENDKLQLEEKLKKKEFDINQQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTA 1130
Query: 4234 KERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAM 4413
+ ++ + + + +ELE+ S LE + + KK E++ + R +++A L +A
Sbjct: 1131 RAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEAT 1190
Query: 4414 SQELRDRETRVLSLLNE-VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKA 4590
+ LR + ++ L E +D ++ ++ ++ + + EL D SN + K LEK
Sbjct: 1191 AAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKV 1250
Query: 4591 KRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRG 4770
R+LE + N+ RV++EE + +L R +L+ N E R + K+ + RG
Sbjct: 1251 SRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTEN----GELARQLEEKEALISQLTRG 1306
Query: 4771 LL---KQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXX 4941
L +Q+ DL+ +LE E + K+ + + L +Q E K E
Sbjct: 1307 KLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKA 1366
Query: 4942 XXXXXEYQIE--------CEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQA 5097
+++ + EE +AK+ +A L++A+ AV A+ L +
Sbjct: 1367 NSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKH----- 1421
Query: 5098 RKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKI-AQXXXXXXXXQSNCELAIDKQRKAQV 5274
R Q R+ + ++K+R KI A+ QS E +Q
Sbjct: 1422 RLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE-------SSQK 1474
Query: 5275 QLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQ 5454
+ ++T+L + +++ ++ +R N++ + +I++L Q
Sbjct: 1475 EARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTE-----------------Q 1517
Query: 5455 YLEDQLNVEGQEKTAANRAARRLEKR--LNDTTQQFEDEKRANEQAKELLEKSNLKNRNL 5628
E NV EK +LE + L + E E+ +A+ LE + +K +
Sbjct: 1518 LGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQ--LEFNQIK-AEI 1574
Query: 5629 RRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
R+L E ++EM + + H+ V LDA + E++
Sbjct: 1575 ERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVL 1614
Score = 129 bits (324), Expect = 9e-28
Identities = 140/753 (18%), Positives = 311/753 (40%), Gaps = 42/753 (5%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + + + +E+ + +R +LE++ QE+ D+ ++ Q + D ++
Sbjct: 848 EKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERC 907
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ L + +E L + + DE L + ++ E A ++
Sbjct: 908 DQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVE 967
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ K A N+ + L +E L +E +K +
Sbjct: 968 KE---------------------KHATENKVKNLTEEMAGL----DEIIAKLTKEKKALQ 1002
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
A Q A + + E+ VN L + + K + V+ L+ LE+ + + + ++K+K++ +L
Sbjct: 1003 EAHQQALDDLQVEEDKVNS-LSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDL 1061
Query: 4279 ---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL 4449
++S M+LEN + + K+ K+F+ ++ ++AL + + ++L++ + R+
Sbjct: 1062 KLTQESIMDLENDKLQLEEKLKK-KEFDINQQNSKIEDEQALALQ--LQKKLKENQARIE 1118
Query: 4450 SLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRV 4629
L E++ + + +++R L +EL++ ++ G + + EAE MR
Sbjct: 1119 ELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRR 1178
Query: 4630 QME----------------------ELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
+E EL + + + + +LE K E D SN +
Sbjct: 1179 DLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNME 1238
Query: 4744 --VEAEEKRRGLLKQIRDLENE----LENEKRGKSGAVSHRKKIENQIGELEQQLEVANR 4905
++A+ + + + D NE LE +R + + R K++ + GEL +QLE
Sbjct: 1239 QIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEA 1298
Query: 4906 LKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA----DRKFRAVEAEREQLRE 5073
L + + + + EE +AK +A L+ A D E E E E
Sbjct: 1299 LISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAE 1358
Query: 5074 ANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAID 5253
L +A + + E K++L ++ + C
Sbjct: 1359 LQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEK 1418
Query: 5254 KQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMA 5433
+ + Q ++E + D+ + ++++ ++ ++K K E +S +S ++ +
Sbjct: 1419 TKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELES-SQKEAR 1477
Query: 5434 ALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNL 5613
+L ++ L++ + R + L++ ++D T+Q + + + +++ ++ +
Sbjct: 1478 SLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEV 1537
Query: 5614 KNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ L+ L+EAE + E K Q E + +
Sbjct: 1538 EKLELQSALEEAEASLEHEEGKILRAQLEFNQI 1570
Score = 96.7 bits (239), Expect = 6e-18
Identities = 110/560 (19%), Positives = 242/560 (42%), Gaps = 27/560 (4%)
Frame = +1
Query: 3046 DHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMG 3225
D +R + +AK +L +L + E+ + S LE+ K +L E+ED +
Sbjct: 1380 DAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNA 1439
Query: 3226 KVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELR---EDMETERNA 3396
L+ + D+ L +Y+E + + QK+ R + T + +L+ E+
Sbjct: 1440 AAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLET 1499
Query: 3397 RNKAEMTRREVVAQLEKVKGDVLDKVDEATML-QDLMSRKDEEVNATKRAIEQIQHTMEG 3573
+ +E ++ L + G+ V E + + L K E +A + A ++H EG
Sbjct: 1500 FKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHE-EG 1558
Query: 3574 KI-------EEQKAKFSRQVEELHDQIEQHKKQRSQ-LEKQQNQADQERADMAQEIALLQ 3729
KI + KA+ R++ E +++EQ K+ + ++ Q D E + + + +
Sbjct: 1559 KILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKK 1618
Query: 3730 ASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFA 3909
D+++ E L AE+ + ++L L+ ++ +LD R ++ + A
Sbjct: 1619 KMEGDLNEM----EIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIA 1674
Query: 3910 NMQRR-------LATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEG 4068
++RR L + I R + L + +L+++K++ E
Sbjct: 1675 IVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMEA 1734
Query: 4069 LRAHLEKEIHAARQGAGEARRKAEESVN---QQLEELRKK--NLRDVEHLQKQLEESEVA 4233
L+ E+ A Q A KA++++ EEL+K+ +E ++K +E++
Sbjct: 1735 DLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKD 1794
Query: 4234 KERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAM 4413
+ L ++I L+ +L+ + A R+ E + + + AE ++K+ +
Sbjct: 1795 LQHRLDEAEQI--ALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKEL 1852
Query: 4414 SQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAK 4593
+ + + + +L L + VD ++ ++ +R ++ + + +N F K HEL++A+
Sbjct: 1853 TYQTEEDKKNLLRLQDLVDKLQLKVK---AYKRQAEEAEEQANTNLSKFRKVQHELDEAE 1909
Query: 4594 RS---LEAELNDMRVQMEEL 4644
E+++N +R + ++
Sbjct: 1910 ERADIAESQVNKLRAKSRDI 1929
>gi|31235859|ref|XP_319312.1| ENSANGP00000025304 [Anopheles gambiae]
gi|30174794|gb|EAA43619.1| ENSANGP00000025304 [Anopheles gambiae str.
PEST]
Length = 1938
Score = 1135 bits (2937), Expect = 0.0
Identities = 679/1918 (35%), Positives = 1082/1918 (56%), Gaps = 33/1918 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K CWVP++ EG+++G IK + V V L + +D V + NPPK++K EDMS
Sbjct: 36 KKACWVPEEKEGYVLGEIKATKGELVTVALPGVQTK-DFKKDLVSQVNPPKYEKCEDMSN 94
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LTYLN+ASVLHNL+ RYY+ LIYTYSGLFCVVINPYK+ P+Y+ + ++GK+R+E+PP
Sbjct: 95 LTYLNDASVLHNLRQRYYAKLIYTYSGLFCVVINPYKRYPLYTNRCAKMYRGKRRNEVPP 154
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
H+FA++D AY +ML E+QS+L TGESGAGKTENTKKVI Y A + GA+ K NA +
Sbjct: 155 HLFAVSDGAYVNMLTNHENQSMLITGESGAGKTENTKKVIAYFATI-GASGKKDENAEKK 213
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
G LE Q++Q NP+LEAFGN+KTV+NDNSSRFGKFIRI+F SG ++G
Sbjct: 214 -------------GSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFTGSGKLAG 260
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSE--YLLEGVDNYRFLVNRGIT 969
A+IE YLLEK+RV+ Q ERS+HIFYQI+ G S K E +L + +Y + IT
Sbjct: 261 ADIETYLLEKARVISQQTLERSYHIFYQIMSG-SVKGLKEMCFLSNDIYDYNSVSQGKIT 319
Query: 970 LPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDR 1149
+PNVDD +E T + ++GF +E +I R+ SAV+ +G ++F Q+ + +QA
Sbjct: 320 IPNVDDGEECLLTDEAFNVLGFTQEEKDNIYRITSAVMHMGRMQFKQKGREEQAEADGTE 379
Query: 1150 VIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWL 1329
+V LLG+ +L K L+PRIKVG EFV K QN++Q +V A+ K ++RLFKWL
Sbjct: 380 DGDRVAKLLGVGTDDLYKNLLKPRIKVGNEFVTKGQNKDQVTNSVGALCKGIFDRLFKWL 439
Query: 1330 VTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQ 1509
V + N++LD T ++ A FIG+LDIAGFEIFD N FEQ+CIN+TNEKLQQ FN+ MF+LEQ
Sbjct: 440 VKKCNETLD-TKQKRAQFIGVLDIAGFEIFDFNGFEQLCINFTNEKLQQFFNHHMFVLEQ 498
Query: 1510 EEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-N 1686
EEY++EGI W FIDFG+DL IDLIEKPMG+L++L+EE +FPKA D++F EKL H
Sbjct: 499 EEYKKEGINWAFIDFGMDLLACIDLIEKPMGILSILEEESMFPKATDQTFAEKLMTNHLG 558
Query: 1687 KHPKFIVPDMRS----KSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFV 1854
K F+ P HFA+ HYAG V Y+ WL KN DPLN+ VV + ++ +
Sbjct: 559 KSAPFMKPRPPKPGIPAGHFAIGHYAGVVSYNITGWLEKNKDPLNDTVVDQFKKGSNALM 618
Query: 1855 AGIWKD--AEFAGICAAEMNETAFGMRSRKGM-FRTVSQLHKEQLTKLMTTLRNTSPHFV 2025
I+ D + A AA+ G R +KG F TVS +KEQL LMTTL++T PHFV
Sbjct: 619 VEIFADHPGQSADPAAAK------GGRGKKGAGFATVSSSYKEQLNNLMTTLKSTQPHFV 672
Query: 2026 RCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVI 2205
RCIIPN K +G ++++LV+ QL CNGVLEGIRICR+GFPNR+ + +F+ RY IL P +
Sbjct: 673 RCIIPNEMKTAGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKLRYMILNPKGV 732
Query: 2206 PKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQ 2385
D K+ + ++ A +D+ LYR+G +KVFFR GVL +EE RD +L+ ++ QA
Sbjct: 733 EAE-KDLKKCAQVIMDAAGLDSELYRLGNTKVFFRAGVLGQMEEFRDERLSKIMSWMQAW 791
Query: 2386 CRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRA 2565
CRG+LSR+ + N YLKLR W WW+L+ KVKPLL V+R +D+I
Sbjct: 792 CRGYLSRKEFKKMQEQRVSLEIVQRNLRKYLKLRTWAWWKLWQKVKPLLNVSRVEDQIAK 851
Query: 2566 KDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTR 2745
+++ +E K E +E E +++ E+ + + L E E + +L +
Sbjct: 852 LEEKATKAQEAYEKEEKLRKELEALNSKLLAEKTALLDSLSGEKGALQEYQEKAAKLTAQ 911
Query: 2746 NQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNV 2925
+LE + D ++RL+ ++K + + DK +
Sbjct: 912 KNDLENQLRDTQERLAQEEDARNQLFQTKKKLEQEIGSQKKDAEDLELQIQKIEQDKASK 971
Query: 2926 DQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQL 3105
D + + +L E++ H K K +LE L
Sbjct: 972 DHQIRNLNDEIAHQDELINKLNKEKKMQGEVNQKTAEELQAAEDKVNHLNKVKAKLEQTL 1031
Query: 3106 HELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQL 3285
ELE L RE++ + ++E+ KRK+ +L+ +++ +A+ +EL ++++D+E+
Sbjct: 1032 DELEDSLEREKKLRGDVEKAKRKVEGDLKLTQEAVADLERNKKELEQTVLRKDKEISALS 1091
Query: 3286 TRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVL 3465
+ ++E + V +QKQ++++Q I+EL E++E ER AR KAE R ++ +LE++ G+ L
Sbjct: 1092 AKLEDEQSLVGKLQKQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEEL-GERL 1150
Query: 3466 DKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQH 3642
++ AT Q +L +++ E+ +R +E+ EG + + K + V E+ +Q++
Sbjct: 1151 EEAGGATSAQIELNKKREAELAKLRRDLEEANIQHEGTLANLRKKHNDAVAEMAEQVD-- 1208
Query: 3643 KKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAE----S 3810
QL K + +A+ +RA+M E+ + + + +++ E ++Q L E
Sbjct: 1209 -----QLNKLKTKAEHDRANMYNELNNTRTACDQLSREKAAQEKIAKQLQHTLNEVQSKL 1263
Query: 3811 DEHKRTLIDQLERSRDEL----DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXX 3978
DE RTL D + S+ +L L R E+ E + + + +
Sbjct: 1264 DETNRTLND-FDASKKKLSIENSDLLRQLEDAESQVSQLSKIKISLTQQLEDTKRLADEE 1322
Query: 3979 TRLKIANINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHAARQGAGEARRKAEE---S 4146
R + + + R LE + + L ++ +EEAEG + +++++ A A R K E +
Sbjct: 1323 ARERATLLGKFRNLEHDLDNLREQVEEEAEG-KGDIQRQLSKANAEAQLWRSKYESEGVA 1381
Query: 4147 VNQQLEELRKK---NLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRAS 4317
++LEE ++K L + E + L + +A E+ +K+++ E+ED +E++ +
Sbjct: 1382 RAEELEEAKRKLQARLAEAEETIESLNQKCIALEK---TKQRLATEVEDLQLEVDRASSI 1438
Query: 4318 HRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEES 4497
+EK+QK F+ + E ++ V + DA +E R+ T + L + +E LE
Sbjct: 1439 ANAAEKKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAV 1498
Query: 4498 DRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDAR 4677
R ++L E++D + + G+N+HE+EK+++ LEAE ++++ +EE E L+ E+
Sbjct: 1499 RRENKNLADEVKDLLDQIGEGGRNIHEIEKSRKRLEAEKDELQAALEEAEAALEQEENKV 1558
Query: 4678 LRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKI 4857
LR ++ ++ E DR I K+ E E R+ + + ++ LE E +GK+ A+ +KK+
Sbjct: 1559 LRAQLELSQVRQEIDRRIQEKEEEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKL 1618
Query: 4858 ENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKF 5037
E I ELE L+ AN+ E + Q EE ++A++D L ++R+
Sbjct: 1619 EADINELEIALDHANKANAEAQKNIKRYQQQLKDVQSALEEEQRARDDAREQLGISERRA 1678
Query: 5038 RAVEAEREQ----LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQX 5205
A++ E E+ L +A+ G QA ++ A+ I++ KR+LE+++
Sbjct: 1679 NALQNELEESRTLLEQADRGRRQAEQELSDAHEQLNEVSAQNASIAA-AKRKLESELQTL 1737
Query: 5206 XXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKI 5385
+ + + +K +KA V ++ +L E+ Q E +++LE+ ++ + ++
Sbjct: 1738 HSDLDELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRL 1797
Query: 5386 TELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDE 5565
E ES A + + LE +V+ LE +L+ E + A + R+ E+R+ + T Q E++
Sbjct: 1798 DEAESNALKGGKKAIQKLEQRVRELESELDSEQRRHADAQKNLRKSERRIKELTFQSEED 1857
Query: 5566 KRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQR---EADDLLDANEQ 5730
++ +E+ ++L++K K + +RQ++EAE+ + K R Q+ EA++ D EQ
Sbjct: 1858 RKNHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADIAEQ 1915
Score = 157 bits (396), Expect = 4e-36
Identities = 202/966 (20%), Positives = 405/966 (41%), Gaps = 78/966 (8%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMK--- 3258
+LE + + ++ +E + + ELE KLLAE D L+ + G ++E + K
Sbjct: 851 KLEEKATKAQEAYEKEEKLRKELEALNSKLLAEKTALLDSLSGEKGALQEYQEKAAKLTA 910
Query: 3259 RDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQ 3438
+ +L++QL E A Q D + + + ++ +E E ++ K ++ Q
Sbjct: 911 QKNDLENQLRDTQERLA-------QEEDARNQLFQTKKKLEQEIGSQKK---DAEDLELQ 960
Query: 3439 LEKVKGDVLDKVDEATMLQDLMSRKDEEVN-----------ATKRAIEQIQHTME--GKI 3579
++K++ D K + L D ++ +DE +N ++ E++Q + +
Sbjct: 961 IQKIEQDKASKDHQIRNLNDEIAHQDELINKLNKEKKMQGEVNQKTAEELQAAEDKVNHL 1020
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKR 3759
+ KAK + ++EL D +E+ KK R +EK + + + + + L Q + AD+++ +
Sbjct: 1021 NKVKAKLEQTLDELEDSLEREKKLRGDVEKAKRKVEGD-------LKLTQEAVADLERNK 1073
Query: 3760 KIHEAHLM----EIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRL 3927
K E ++ EI A L+ E +++L+ +L++ EL R+ E EE A Q R
Sbjct: 1074 KELEQTVLRKDKEISA-LSAKLEDEQSLVGKLQKQIKELQA--RIEELEEEVEAERQARA 1130
Query: 3928 ATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAE--GLRAHLEKEIHA 4101
RL+ A + Q+E L++K EAE LR LE E +
Sbjct: 1131 KAEKQRADLARELEELGERLEEAGGATSAQIE------LNKKREAELAKLRRDLE-EANI 1183
Query: 4102 ARQGA-GEARRKAEESVNQ------QLEELRKKNLRDVEHLQKQLEESEVAKERILQSK- 4257
+G R+K ++V + QL +L+ K D ++ +L + A +++ + K
Sbjct: 1184 QHEGTLANLRKKHNDAVAEMAEQVDQLNKLKTKAEHDRANMYNELNNTRTACDQLSREKA 1243
Query: 4258 ------KKIQQELEDSSMELENVRASHRDSEKRQKKFE-----------------SQMAE 4368
K++Q L + +L+ + D + +KK SQ+++
Sbjct: 1244 AQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSIENSDLLRQLEDAESQVSQLSK 1303
Query: 4369 ERVAVQKALLDRDAMS-QELRDRET---RVLSLLNEVDIMKEHLEESDRVRRSLQQELQD 4536
++++ + L D ++ +E R+R T + +L +++D ++E +EE + +Q++L
Sbjct: 1304 IKISLTQQLEDTKRLADEEARERATLLGKFRNLEHDLDNLREQVEEEAEGKGDIQRQLSK 1363
Query: 4537 SISN--------KDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEV 4692
+ + + + ELE+AKR L+A L + +E L E + RL
Sbjct: 1364 ANAEAQLWRSKYESEGVARAEELEEAKRKLQARLAEAEETIESLNQKCIALEKTKQRLAT 1423
Query: 4693 TNQALKSESDRAISNKDVEAEEKRRGLLK-------QIRDLENELENEKRGKSGAVSHRK 4851
+ L+ E DRA S + AE+K++ K ++ DL EL+ ++ +
Sbjct: 1424 EVEDLQLEVDRASSIANA-AEKKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELF 1482
Query: 4852 KIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADR 5031
+++ E ++QLE R E + +D+ + E R
Sbjct: 1483 RLKGAYEEGQEQLEAVRR---------------------ENKNLADEVKDLLDQIGEGGR 1521
Query: 5032 KFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXX 5211
+E R++L + L A ++ + S+ ++ ++ +I +
Sbjct: 1522 NIHEIEKSRKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEIDRRIQEKEE 1581
Query: 5212 XXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITE 5391
+ N + A+D SM+ +L + + + ++L R + +A I E
Sbjct: 1582 EFENTRKNHQRALD----------------SMQASLEAEAKGKAEAL-RMKKKLEADINE 1624
Query: 5392 LESGAQSRARAQMAA---LEAKVQYLEDQLNVEGQEKTAANRAARRL---EKRLNDTTQQ 5553
LE +A A ++ Q L+D + +E+ A + A +L E+R N +
Sbjct: 1625 LEIALDHANKANAEAQKNIKRYQQQLKDVQSALEEEQRARDDAREQLGISERRANALQNE 1684
Query: 5554 FEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQL 5733
E+ + EQA ++ + + QL+E + + R ++ E L ++L
Sbjct: 1685 LEESRTLLEQADRGRRQAEQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDEL 1744
Query: 5734 TRELMN 5751
E N
Sbjct: 1745 LNEAKN 1750
Score = 109 bits (272), Expect = 9e-22
Identities = 138/637 (21%), Positives = 266/637 (41%), Gaps = 88/637 (13%)
Frame = +1
Query: 3028 LTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDH 3207
L QL D E + K K L QL + ++ + E + ++ L R L +L++ ++
Sbjct: 1287 LLRQLEDAESQVSQLSKIKISLTQQLEDTKRLADEEARERATLLGKFRNLEHDLDNLREQ 1346
Query: 3208 LAEKMGKVEELNNQLMKRDEELQHQLTRYDEES-ANVTLMQKQMRDMQTTIDELREDMET 3384
+ E+ ++ QL K + E Q ++Y+ E A +++ R +Q + E E +E+
Sbjct: 1347 VEEEAEGKGDIQRQLSKANAEAQLWRSKYESEGVARAEELEEAKRKLQARLAEAEETIES 1406
Query: 3385 ERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRK----DEEVNATKRAIEQ 3552
E T++ + ++E D+ +VD A+ + + +K D+ + K ++
Sbjct: 1407 LNQKCIALEKTKQRLATEVE----DLQLEVDRASSIANAAEKKQKAFDKIIGEWKLKVDD 1462
Query: 3553 IQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQA 3732
+ ++ +E + +S ++ L E+ ++Q + ++ E D+ +I
Sbjct: 1463 LAAELDASQKECR-NYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGR 1521
Query: 3733 SRADIDKKRKIHEAHLMEIQANLAESD-----EHKRTLIDQLERS--RDELDHLNRVREE 3891
+ +I+K RK EA E+QA L E++ E + L QLE S R E+D + +EE
Sbjct: 1522 NIHEIEKSRKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEIDRRIQEKEE 1581
Query: 3892 E-EHAFANMQRRLATAXXXXXXXXXXXXXXTRLKI---ANINRARQLEDEKNALLDE--- 4050
E E+ N QR L + R+K A+IN D N E
Sbjct: 1582 EFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQK 1641
Query: 4051 -----KEEAEGLRAHLEKEIHA---ARQGAGEARRKAEESVNQ---------QLEELRKK 4179
+++ + +++ LE+E A AR+ G + R+A N+ Q + R++
Sbjct: 1642 NIKRYQQQLKDVQSALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRRQ 1701
Query: 4180 NLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKF--- 4350
+++ +QL E I +K+K++ EL+ +L+ + ++SE++ KK
Sbjct: 1702 AEQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDELLNEAKNSEEKAKKAMVD 1761
Query: 4351 ------ESQMAEERVAVQKALLDRDAMSQELRDR----------------------ETRV 4446
E + ++ Q+ L R A+ Q++++ E RV
Sbjct: 1762 AARLADELRAEQDHAQTQEKL--RKALEQQIKELQVRLDEAESNALKGGKKAIQKLEQRV 1819
Query: 4447 LSLLNEVDI-MKEHLE-------------------ESDRVRRSLQQELQDSISNK-DDFG 4563
L +E+D + H + E DR Q+L D + K +
Sbjct: 1820 RELESELDSEQRRHADAQKNLRKSERRIKELTFQSEEDRKNHERMQDLVDKLQQKIKTYK 1879
Query: 4564 KNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDA 4674
+ + E E+ A+ + ++EE E+ IAE A
Sbjct: 1880 RQIEEAEEIAALNLAKFRKAQQELEEAEERADIAEQA 1916
Score = 89.4 bits (220), Expect = 1e-15
Identities = 105/527 (19%), Positives = 229/527 (42%), Gaps = 6/527 (1%)
Frame = +1
Query: 4180 NLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQ 4359
N+ VE +LEE + + ++K+++ELE + +L + + DS +K
Sbjct: 841 NVSRVEDQIAKLEEKATKAQEAYEKEEKLRKELEALNSKLLAEKTALLDSLSGEK---GA 897
Query: 4360 MAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDS 4539
+ E + K ++ + +LRD + R L E D + + ++ L+QE+
Sbjct: 898 LQEYQEKAAKLTAQKNDLENQLRDTQER---LAQEEDARNQLFQ----TKKKLEQEIGSQ 950
Query: 4540 ISNKDDFGKNVHELEKAKRSLEAE---LNDMRVQMEELEDNLQIAEDARLRLEVTNQALK 4710
+ +D + ++E+ K S + + LND +EL + L ++ +++ EV +
Sbjct: 951 KKDAEDLELQIQKIEQDKASKDHQIRNLNDEIAHQDELINKLN--KEKKMQGEVNQKT-- 1006
Query: 4711 SESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
+E +A +K + + L + + +LE+ LE EK+ + ++K+E + ++ +
Sbjct: 1007 AEELQAAEDKVNHLNKVKAKLEQTLDELEDSLEREKKLRGDVEKAKRKVEGDLKLTQEAV 1066
Query: 4891 EVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLR 5070
R K+E + +I A+ ED +L+ + ++ + ++A E+L
Sbjct: 1067 ADLERNKKELEQTVLRK-----DKEISALSAKL--EDEQSLVGKLQKQIKELQARIEELE 1119
Query: 5071 EANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAI 5250
E E QAR AK ++ R LE + + EL
Sbjct: 1120 EEVEAERQAR--------------AKAEKQRADLARELEELGERLEEAGGATSAQIEL-- 1163
Query: 5251 DKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELE---SGAQSRAR 5421
+K + +L ++ DL ++ T A +L + + D A++ E + +++A
Sbjct: 1164 --NKKREAELAKLRRDLEEANIQHEGTLA---NLRKKHNDAVAEMAEQVDQLNKLKTKAE 1218
Query: 5422 AQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLE 5601
A + ++ + +EK A + A++L+ LN+ + ++ R +
Sbjct: 1219 HDRANMYNELNNTRTACDQLSREKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKK 1278
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
K +++N +L RQL++AE ++S+ ++ ++ +D ++ RE
Sbjct: 1279 KLSIENSDLLRQLEDAESQVSQLSKIKISLTQQLEDTKRLADEEARE 1325
Score = 79.7 bits (195), Expect = 8e-13
Identities = 81/418 (19%), Positives = 183/418 (43%), Gaps = 25/418 (5%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L +Q+ E ++++ + + LE K +L A LE+++ L ++ KV +L + +E
Sbjct: 1512 LLDQIGEGGRNIHEIEKSRKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQE 1571
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ ++ +EE N ++ Q +D ++ +E E + +A ++++ A + ++
Sbjct: 1572 IDRRIQEKEEEFENTR------KNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINEL 1625
Query: 3451 KGDVLDKVDEATM-LQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+ LD ++A Q + R +++ + A+E+ Q + EQ R+ L +
Sbjct: 1626 E-IALDHANKANAEAQKNIKRYQQQLKDVQSALEEEQRARDDA-REQLGISERRANALQN 1683
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL-- 3801
++E+ + Q ++ + QA+QE +D +++ + A A I ++ E+ L + ++L
Sbjct: 1684 ELEESRTLLEQADRGRRQAEQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDE 1743
Query: 3802 ----AESDEHKRT--------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
A++ E K L D+L +D ++R+ E +Q RL A
Sbjct: 1744 LLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAESN 1803
Query: 3946 XXXXXXXXXXXTRLKIANIN------RARQLEDEKNALLDEKEEAE-GLRAHLEKEIHAA 4104
++ + + R + +KN E+ E ++ +++ H
Sbjct: 1804 ALKGGKKAIQKLEQRVRELESELDSEQRRHADAQKNLRKSERRIKELTFQSEEDRKNHER 1863
Query: 4105 RQGAGEARRKAEESVNQQLEELRK---KNLRDVEHLQKQLEESEVAKERILQSKKKIQ 4269
Q + ++ ++ +Q+EE + NL Q++LEE+E + Q+ K +
Sbjct: 1864 MQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADIAEQAATKFR 1921
Score = 53.9 bits (128), Expect = 5e-05
Identities = 62/408 (15%), Positives = 157/408 (38%), Gaps = 12/408 (2%)
Frame = +1
Query: 2533 QVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAE 2712
++ ++ + A+ DEL+A E + E + E K+ + +E + +++++ + + E
Sbjct: 1525 EIEKSRKRLEAEKDELQAALE---EAEAALEQEENKVLRAQLELSQVRQEIDRRIQEKEE 1581
Query: 2713 LDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXX 2892
+ + + ++ M+ L ++K + +
Sbjct: 1582 ------EFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKA 1635
Query: 2893 XXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHG 3072
+ Q Q A D L +L + +
Sbjct: 1636 NAEAQKNIKRYQQQLKDVQSALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQA 1695
Query: 3073 VKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQL 3252
+ + + E +L + + LN + + KRKL +EL+ L E + + + +
Sbjct: 1696 DRGRRQAEQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDELLNEAKNSEEKA 1755
Query: 3253 MKR-------DEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELRED-METERNARNKA 3408
K +EL+ + + +++Q++++Q +DE + ++ + A K
Sbjct: 1756 KKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAESNALKGGKKAIQKL 1815
Query: 3409 EMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQ 3588
E RE+ ++L+ + D + + + ++ E++Q ++ K++++
Sbjct: 1816 EQRVRELESELDSEQRRHADAQKNLRKSERRIKELTFQSEEDRKNHERMQDLVD-KLQQK 1874
Query: 3589 KAKFSRQVEELHD----QIEQHKKQRSQLEKQQNQADQERADMAQEIA 3720
+ RQ+EE + + + +K + +LE+ + ERAD+A++ A
Sbjct: 1875 IKTYKRQIEEAEEIAALNLAKFRKAQQELEEAE-----ERADIAEQAA 1917
>gi|42662294|ref|XP_371398.2| myosin, heavy polypeptide 7B, cardiac
muscle, beta [Homo sapiens]
Length = 1983
Score = 1135 bits (2937), Expect = 0.0
Identities = 673/1897 (35%), Positives = 1053/1897 (55%), Gaps = 16/1897 (0%)
Frame = +1
Query: 67 WAQRKLCWVPDQNEGFLIGSIKRE-TNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIE 243
W +K WVPD+ + ++ +K E T V VE D + + + ++Q NPP+FD +E
Sbjct: 71 WDGKKRVWVPDEQDAYVEAEVKSEATGGRVTVETKD-QKVLMVREAELQPMNPPRFDLLE 129
Query: 244 DMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRH 423
DM+ +T+LNEASVLHNL+ RY +IYTYSGLFCV INPYK LP+Y+ ++ +KGK+R
Sbjct: 130 DMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCVTINPYKWLPVYTASVVAAYKGKRRS 189
Query: 424 EMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLN 603
+ PPHI+A+AD AY ML+ R++QS+L TGESGAGKT NTK+VIQY A VA
Sbjct: 190 DSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAGKTVNTKRVIQYFAIVAALGDGPGKK 249
Query: 604 AAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSG 783
A Q + K G LE Q+++ANP +EAFGN+KT++NDNSSRFGKFIRI+F SG
Sbjct: 250 A---QFLATKTG-----GTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPSG 301
Query: 784 YISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLE-GVDNYRFLVNR 960
++ A+I+ YLLEKSRV+ Q ERS+H++YQIL G + + LL +Y F
Sbjct: 302 KLASADIDSYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQDMLLLSMNPYDYHFCSQG 361
Query: 961 GITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQ 1140
IT+ N++D +E +T ++M I+GF+ DE + ++V A+L GN++F Q+++ +QA
Sbjct: 362 VITVDNMNDGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNMKFKQKQREEQAEAD 421
Query: 1141 DDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLF 1320
K +L+G+ +L K L PR++VG E+V K Q+ EQ FAV A+AKA+Y+RLF
Sbjct: 422 GTESADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQVVFAVGALAKATYDRLF 481
Query: 1321 KWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFI 1500
+WLV+RIN++LD T FIG+LDIAGFEIF+ NSFEQ+CIN+TNEKLQQ FN MF+
Sbjct: 482 RWLVSRINQTLD-TKLPRQFFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNQHMFV 540
Query: 1501 LEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKT 1680
LEQEEY+REGI+W FIDFGLDLQP IDLIEKP+G+L++L+EEC+FPKA+D SF KL
Sbjct: 541 LEQEEYKREGIDWVFIDFGLDLQPCIDLIEKPLGILSILEEECMFPKASDASFRAKLYDN 600
Query: 1681 H-NKHPKFIV--PDMRSK--SHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTD 1845
H K P F PD + K +HF VVHYAG V YS WL KN DPLNE VV + Q S +
Sbjct: 601 HAGKSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNKDPLNETVVPIFQKSQN 660
Query: 1846 PFVAGIWKDAEFAGICAAEMNETAFGMRSRK-GMFRTVSQLHKEQLTKLMTTLRNTSPHF 2022
+A ++++ +AG C+ E ++ + +K F+TVSQLHKE L KLMT LR T PHF
Sbjct: 661 RLLATLYEN--YAGSCSTEPPKSGVKEKRKKAASFQTVSQLHKENLNKLMTNLRATQPHF 718
Query: 2023 VRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDV 2202
VRCI+PN K G +++ LVL QLRCNGVLEGIRICRQGFPNR+ + +FR RY IL P
Sbjct: 719 VRCIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLLYTDFRQRYRILNPSA 778
Query: 2203 IPKN-FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQ 2379
IP + F+D +++ K++ +LD+D Y+ G +KVFF+ G+L LEE RD +L ++ Q
Sbjct: 779 IPDDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVFFKAGLLGVLEELRDQRLAKVLTLLQ 838
Query: 2380 AQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEI 2559
A+ RG L R Y N A+ ++NW W +LF K+KPLL+ + ++E+
Sbjct: 839 ARSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAVKNWSWMKLFFKMKPLLRSAQAEEEL 898
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
A ELR + L E +E E+ + E+ + QLQ E +N A+ ++ L
Sbjct: 899 AALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHLLI 958
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
+LE V ++ +RL RRK + + +K
Sbjct: 959 KSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKEKQ 1018
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLEN 3099
+ ++ L E+R KAK RLE
Sbjct: 1019 ATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQ 1078
Query: 3100 QLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQH 3279
Q+ +LE L +E++ + + E+ KRKL +L+ +++ +A+ ++L +L K+D EL
Sbjct: 1079 QVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQ 1138
Query: 3280 QLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGD 3459
R ++E MQK+++++Q +EL E++E ER AR + E R E +LE++
Sbjct: 1139 LSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSER 1198
Query: 3460 VLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQ 3639
+ + + ++ +++ E+ +R +E+ E + + K + EL +Q++
Sbjct: 1199 LEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDS 1258
Query: 3640 HKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEH 3819
++ R +LEK++++ E D+A + L ++A +K + +E L E + + E
Sbjct: 1259 LQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQ 1318
Query: 3820 KRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIAN 3999
Q R + E L+R+ EE+E + + R A A ++ K A
Sbjct: 1319 LADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSAL 1378
Query: 4000 INRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKK 4179
+ + L + + L ++ EE +A L++ + A + R K E Q+ EEL +
Sbjct: 1379 AHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEA 1438
Query: 4180 NLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKF 4350
+ LQ+ E E A + + ++K ++Q E ED ++ELE ++ +K+Q+
Sbjct: 1439 KKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHL 1498
Query: 4351 ESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQEL 4530
E + E R ++ + +A +E R T + L + + E LE R ++LQ+E+
Sbjct: 1499 ERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEI 1558
Query: 4531 QDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALK 4710
D GK++ ELEK K++LE E ++++ +EE E L++ E LR+++ +K
Sbjct: 1559 SDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVK 1618
Query: 4711 SESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
+E DR ++ KD E RR + + L+ L+ E R ++ A+ +KK+E + +LE QL
Sbjct: 1619 AEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQL 1678
Query: 4891 EVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLR 5070
A R E E Q +E ++ ++ + +R+ + AE E+LR
Sbjct: 1679 GHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELR 1738
Query: 5071 EANEGLMQARK----QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNC 5238
A E ++R+ + ++ G+ + +K++LEA +AQ
Sbjct: 1739 AALEQGERSRRLAEQELLEATERLNLLHSQNTGLLN-QKKKLEADLAQLSGEVEEAAQER 1797
Query: 5239 ELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRA 5418
A +K +KA + +L E+ + E K++LE++ R+ +A++ E E A
Sbjct: 1798 REAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGG 1857
Query: 5419 RAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELL 5598
+ Q+ LEAKV+ LE +L+ E ++ A + R+ E+R+ + Q E++++ + ++L+
Sbjct: 1858 KKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLV 1917
Query: 5599 EKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+K K ++ +RQ +EAE + + K+R Q E DD
Sbjct: 1918 DKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDD 1954
Score = 103 bits (256), Expect = 7e-20
Identities = 158/731 (21%), Positives = 299/731 (40%), Gaps = 40/731 (5%)
Frame = +1
Query: 3679 QADQERADMAQEIALLQASRADIDKKRK-IHEAHL----------MEIQA---NLAESDE 3816
QA++E A + E+ L+ + A + KR+ + E H+ +++QA NLA+++E
Sbjct: 893 QAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEE 952
Query: 3817 HKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIA 3996
LI + ++ L+ E+EE A++ R
Sbjct: 953 RCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAAR------------------------ 988
Query: 3997 NINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAAR---QGAGEARRKAEESVNQQLEE 4167
R+LEDE L + ++ + A EKE A + E +ESV + +E
Sbjct: 989 ----RRKLEDECTELKKDIDDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKE 1044
Query: 4168 LRKKNLRDVEHLQKQLEESEVAKERI---LQSKKKIQQELEDSSMELENVRASHRDSEKR 4338
KK L++ Q+ L + + ++R+ ++K +++Q++ED LE + D+E+
Sbjct: 1045 --KKALQEAH--QQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERA 1100
Query: 4339 QKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSL 4518
++K E + + +V A D+ + ++L+ +++ E+ + +E+ + +
Sbjct: 1101 KRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDS-------ELSQLSLRVEDEQLLGAQM 1153
Query: 4519 QQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTN 4698
Q K + EL+ LE EL R +E Q AE AR E++
Sbjct: 1154 Q--------------KKIKELQARAEELEEELEAERAARARVEK--QRAEAARELEELSE 1197
Query: 4699 QALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGEL 4878
+ ++ A + E G L+ R+LE E R ++ + R+K EL
Sbjct: 1198 RLEEAGGASAGQREGCRKREAELGRLR--RELE---EAALRHEATVAALRRKQAEGAAEL 1252
Query: 4879 EQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAER 5058
+Q++ R++++ E ++E ++ E + A++ R E
Sbjct: 1253 GEQVDSLQRVRQKLEKEKS-------ELRMEVDDLAANVETLTRAKASAEKLCRTYE--- 1302
Query: 5059 EQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISS--EEKRRLEAKIAQXXXXXXXXQS 5232
+QL EA + + ++Q + + G +S EEK L +++++
Sbjct: 1303 DQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLE 1362
Query: 5233 NCELAIDKQRKAQVQLEQITTDLSMERTL---NQKTEAEKQS-LERSNRDYKAKITELES 5400
++++ KA+ L L + L + EAE Q+ L+R A++ + S
Sbjct: 1363 ELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRS 1422
Query: 5401 GAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANE 5580
++ A + LE + L +L + AAN LEK + ED E
Sbjct: 1423 KYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELE 1482
Query: 5581 QAKELLEKSNLKNRNLRRQLDE---AEDEMSRE-----------RTKHRNVQREADDLLD 5718
+A + K R+L R L+E E+EM RE T+ ++ ++ L+
Sbjct: 1483 RATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALE 1542
Query: 5719 ANEQLTRELMN 5751
A E L RE N
Sbjct: 1543 ALETLKRENKN 1553
>gi|191618|gb|AAA37159.1| alpha cardiac myosin heavy chain
Length = 1938
Score = 1135 bits (2936), Expect = 0.0
Identities = 656/1898 (34%), Positives = 1059/1898 (55%), Gaps = 20/1898 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
R C+VPD E ++ + +V E + + VTI D V + NPPKFDKIEDM+
Sbjct: 34 RTECFVPDDKEEYVKAKVVSREGGKVTAE-TENGKTVTIKEDQVMQQNPPKFDKIEDMAM 92
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LT+L+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PP
Sbjct: 93 LTFLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPP 152
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAG-ATRNKSLNAAA 612
HIF+I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A R+K N A
Sbjct: 153 HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRSKKENPNA 212
Query: 613 QQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYIS 792
+ G LE Q++QANP LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++
Sbjct: 213 NK------------GTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLA 260
Query: 793 GANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYL-----LEGVDNYRFLVN 957
A+IE YLLEKSRV+ Q + ER++HIFYQIL + +K E L +Y F+
Sbjct: 261 SADIETYLLEKSRVIFQLKAERNYHIFYQIL----SNKKPELLDMLLVTNNPYDYAFVSQ 316
Query: 958 RGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAML 1137
+++ ++DD +E +T ++ ++ F +E + + ++ A++ GN++F Q+++ +QA
Sbjct: 317 GEVSVASIDDSEELLATDSAFDVLSFTAEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEP 376
Query: 1138 QDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERL 1317
K +L+GL +L K PR+KVG E+V K Q+ +Q +++ A+AK+ YE++
Sbjct: 377 DGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKSVYEKM 436
Query: 1318 FKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMF 1497
F W+VTRIN +L+ T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF
Sbjct: 437 FNWMVTRINATLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMF 495
Query: 1498 ILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQK 1677
+LEQEEY++EGIEW+FIDFG+DLQ IDLIEKPMG++++L+EEC+FPKA D +F KL
Sbjct: 496 VLEQEEYKKEGIEWEFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKAADMTFKAKLYD 555
Query: 1678 TH-NKHPKFIVP---DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTD 1845
H K F P + ++HF++VHYAG VDY+ WL KN DPLNE VVGL Q S+
Sbjct: 556 NHLGKSNNFQKPRNVKGKQEAHFSLVHYAGTVDYNIMGWLEKNKDPLNETVVGLYQKSSL 615
Query: 1846 PFVAGIWKDAEFAGICAAEMNETAFGMRSRK--GMFRTVSQLHKEQLTKLMTTLRNTSPH 2019
+A + F+ +A+ ++ G +K F+TVS LH+E L KLMT L+ T PH
Sbjct: 616 KLMATL-----FSTYASADTGDSGKGKGGKKKGSSFQTVSALHRENLNKLMTNLKTTHPH 670
Query: 2020 FVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPD 2199
FVRCIIPN K G +++ LV+ QLRCNGVLEGIRICR+GFPNR+ + +FR RY IL P
Sbjct: 671 FVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPA 730
Query: 2200 VIPK-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNF 2376
IP+ FID ++ K++ +LDID N Y+ G +KVFF+ G+L LEE RD +L+ +I
Sbjct: 731 AIPEGQFIDSRKGAEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRI 790
Query: 2377 QAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDE 2556
QAQ RG L R + N A++ ++NW W +L+ K+KPLL+ T+ E
Sbjct: 791 QAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKE 850
Query: 2557 IRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRL 2736
+ +E K+ L K E +E E+K+ ++ E+ +Q Q+Q E +N + ++ +L
Sbjct: 851 MANMKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQL 910
Query: 2737 QTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDK 2916
+LE V +M +RL +RK + + +K
Sbjct: 911 IKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 970
Query: 2917 TNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLE 3096
+ + L E++ K+K +LE
Sbjct: 971 HATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKSKVKLE 1030
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
Q+ +LE L +E++ + +LE+ KRKL +L+ +++ + + +L +L K++ ++
Sbjct: 1031 QQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDIS 1090
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
Q ++ ++E A +QK++++ Q I+EL E++E ER AR K E R ++ +LE++
Sbjct: 1091 QQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEI-S 1149
Query: 3457 DVLDKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQI 3633
+ L++ AT +Q M++K E E +R +E+ E + K + V EL +QI
Sbjct: 1150 ERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQI 1209
Query: 3634 EQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESD 3813
+ ++ + +LEK++++ E D+ + + ++A+++K + E E + L E+
Sbjct: 1210 DNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQ 1269
Query: 3814 EHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKI 3993
Q + + E L R EE+E + + R + + K
Sbjct: 1270 RSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKN 1329
Query: 3994 ANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELR 4173
A + + + + L ++ EE +A L++ + A + R K E Q+ EEL
Sbjct: 1330 ALAHALQSSRHDCDLLREQYEEEMEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELE 1389
Query: 4174 KKNLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQK 4344
+ + + LQ E E + + ++K ++Q E+ED +++E A+ +K+Q+
Sbjct: 1390 EAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR 1449
Query: 4345 KFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQ 4524
F+ +AE + +++ + ++ +E R T + L N + EHLE R ++LQ+
Sbjct: 1450 NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQE 1509
Query: 4525 ELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQA 4704
E+ D + GKNVHELEK ++ LE E +++ +EE E +L+ E LR ++
Sbjct: 1510 EISDLTEQLGEGGKNVHELEKIRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQ 1569
Query: 4705 LKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQ 4884
+K+E +R ++ KD E E+ +R L+ + L+ L+ E R ++ A+ +KK+E + E+E
Sbjct: 1570 IKAEIERKLAEKDEEMEQAKRNHLRMVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEI 1629
Query: 4885 QLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQ 5064
QL ANR+ E + Q++ ++A A +D+ + +R+ ++AE E+
Sbjct: 1630 QLSQANRIASEAQKHLKNSQAHLKDTQLQLDDAVHANDDLKENIAIVERRNNLLQAELEE 1689
Query: 5065 LREANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSN 5235
LR E ++RK Q +K+++E+ + Q
Sbjct: 1690 LRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQTEVEEAVQE 1749
Query: 5236 CELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSR 5415
C A +K +KA + +L E+ + E K+++E++ +D + ++ E E A
Sbjct: 1750 CRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKG 1809
Query: 5416 ARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKEL 5595
+ Q+ LEA+V+ LE++L E + + + R+ E+R+ + T Q E++K+ + ++L
Sbjct: 1810 GKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLMRLQDL 1869
Query: 5596 LEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
++K LK + +RQ +EAE++ + +K R VQ E D+
Sbjct: 1870 VDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDE 1907
Score = 154 bits (388), Expect = 3e-35
Identities = 185/873 (21%), Positives = 374/873 (42%), Gaps = 17/873 (1%)
Frame = +1
Query: 3181 AELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTID 3360
AE E ++ E+ G+V++ + R +EL+ ++ V+L+Q++ +
Sbjct: 845 AETEKEMANMKEEFGRVKDALEKSEARRKELEEKM---------VSLLQEK--------N 887
Query: 3361 ELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT-MLQDLMSRKDEEVNATK 3537
+L+ ++ E++ N AE E QL K K + KV E T L+D +EE+NA
Sbjct: 888 DLQLQVQAEQDNLNDAE----ERCDQLIKNKIQLEAKVKEMTERLED-----EEEMNA-- 936
Query: 3538 RAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEI 3717
++ +K K + EL I+ + +++EK+++ + + ++ +E+
Sbjct: 937 ------------ELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEM 984
Query: 3718 ALLQASRADIDKKRK-IHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEE 3894
A L A + K++K + EAH + AE D+ TL + ++D L E+E
Sbjct: 985 AGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK-VNTLTKSKVKLEQQVDDLEGSLEQE 1043
Query: 3895 EHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLR 4074
+ +++R R+LE + + + E +
Sbjct: 1044 KKVRMDLERA----------------------------KRKLEGDLKLTQESIMDLENDK 1075
Query: 4075 AHLEKEIHAARQGAGEARRKAEE--SVNQQLEELRKKNLRDVEHLQKQLEESEVAKERIL 4248
LE+++ + K E+ ++ QL++ K+N +E L+++LE A+ ++
Sbjct: 1076 LQLEEKLKKKEFDISQQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVE 1135
Query: 4249 QSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELR 4428
+ + + +ELE+ S LE + + KK E++ + R +++A L +A + LR
Sbjct: 1136 KLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALR 1195
Query: 4429 DRETRVLSLLNE-VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLE 4605
+ ++ L E +D ++ ++ ++ + + EL D SN + K LEK R+LE
Sbjct: 1196 KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLE 1255
Query: 4606 AELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLL--- 4776
+ N+ RV++EE + +L R +L+ N E R + K+ + RG L
Sbjct: 1256 DQANEYRVKLEEAQRSLNDFTTQRAKLQTEN----GELARQLEEKEALISQLTRGKLSYT 1311
Query: 4777 KQIRDLENELENEKRGKSGAV----SHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXX 4944
+Q+ DL+ +LE E + K+ S R + + E+++E L+
Sbjct: 1312 QQMEDLKRQLEEEGKAKNALAHALQSSRHDCDLLREQYEEEMEAKAELQRVLSKANSEVA 1371
Query: 4945 XXXXEYQIEC----EEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXX 5112
+Y+ + EE +AK+ +A L++A+ AV A+ L + R Q
Sbjct: 1372 QWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKH-----RLQNE 1426
Query: 5113 XXXXXXXXXRAKGGGISSEEKRRLEAKI-AQXXXXXXXXQSNCELAIDKQRKAQVQLEQI 5289
R+ + ++K+R KI A+ QS E +Q + +
Sbjct: 1427 IEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE-------SSQKEARSL 1479
Query: 5290 TTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQ 5469
+T+L + +++ ++ +R N++ + +I++L + + +++ + Q
Sbjct: 1480 STELFKLKNAYEESLEHLETFKRENKNLQEEISDL-----TEQLGEGGKNVHELEKIRKQ 1534
Query: 5470 LNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEA 5649
L VE E L+ L + E E+ +A+ LE + +K + R+L E
Sbjct: 1535 LEVEKLE----------LQSALEEAEASLEHEEGKILRAQ--LEFNQIK-AEIERKLAEK 1581
Query: 5650 EDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
++EM + + H + LDA + E +
Sbjct: 1582 DEEMEQAKRNHLRMVDSLQTSLDAETRSRNEAL 1614
Score = 130 bits (326), Expect = 5e-28
Identities = 144/755 (19%), Positives = 314/755 (41%), Gaps = 44/755 (5%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + + D +E+ + +R +LE++ QE+ D+ ++ Q + D ++
Sbjct: 848 EKEMANMKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERC 907
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ L + +E L + + DE L + ++ E A ++
Sbjct: 908 DQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVE 967
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ K A N+ + L +E A LDE + A L KE
Sbjct: 968 KE---------------------KHATENKVKNLTEEM-AGLDE------IIAKLTKEKK 999
Query: 4099 AARQGAGEARR--KAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQ 4272
A ++ +A +AEE L + + K + V+ L+ LE+ + + + ++K+K++
Sbjct: 1000 ALQEAHQQALDDLQAEEDKVNTLTKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEG 1059
Query: 4273 EL---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETR 4443
+L ++S M+LEN + + K+ K+F+ ++ ++AL + + ++L++ + R
Sbjct: 1060 DLKLTQESIMDLENDKLQLEEKLKK-KEFDISQQNSKIEDEQALALQ--LQKKLKENQAR 1116
Query: 4444 VLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDM 4623
+ L E++ + + +++R L +EL++ ++ G + + EAE M
Sbjct: 1117 IEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKM 1176
Query: 4624 RVQME----------------------ELEDNLQIAEDARLRLEVTNQALKSESDRAISN 4737
R +E EL + + + + +LE K E D SN
Sbjct: 1177 RRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 1236
Query: 4738 KD--VEAEEKRRGLLKQIRDLENE----LENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
+ ++A+ + + + D NE LE +R + + R K++ + GEL +QLE
Sbjct: 1237 MEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEK 1296
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLR----EADRKFRAVEAEREQL 5067
L + + + + EE +AK +A L+ + D E E E
Sbjct: 1297 EALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSSRHDCDLLREQYEEEMEAK 1356
Query: 5068 REANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELA 5247
E L +A + + E K++L ++ + C
Sbjct: 1357 AELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSL 1416
Query: 5248 IDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQ 5427
+ + Q ++E + D+ + ++++ ++ ++K K E +S +S ++ +
Sbjct: 1417 EKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELES-SQKE 1475
Query: 5428 MAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKS 5607
+L ++ L++ + R + L++ ++D T+Q + + + +++ ++
Sbjct: 1476 ARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKIRKQL 1535
Query: 5608 NLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
++ L+ L+EAE + E K Q E + +
Sbjct: 1536 EVEKLELQSALEEAEASLEHEEGKILRAQLEFNQI 1570
Score = 99.4 bits (246), Expect = 1e-18
Identities = 130/575 (22%), Positives = 257/575 (44%), Gaps = 42/575 (7%)
Frame = +1
Query: 3046 DHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMG 3225
D +R + +AK +L +L + E+ + S LE+ K +L E+ED +
Sbjct: 1380 DAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNA 1439
Query: 3226 KVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELR-------EDMET 3384
L+ + D+ L +Y+E + + QK+ R + T + +L+ E +ET
Sbjct: 1440 AAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLET 1499
Query: 3385 -ERNARNKAE----MTRR-----EVVAQLEKVKGDV-LDKVDEATMLQDL---------- 3501
+R +N E +T + + V +LEK++ + ++K++ + L++
Sbjct: 1500 FKRENKNLQEEISDLTEQLGEGGKNVHELEKIRKQLEVEKLELQSALEEAEASLEHEEGK 1559
Query: 3502 MSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQ 3681
+ R E N K IE+ + ++E+ K R V+ L ++ + R++ + + +
Sbjct: 1560 ILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRMVDSLQTSLDAETRSRNEALRVKKK 1619
Query: 3682 ADQERADMAQEIALLQASR--ADIDKKRKIHEAHLMEIQANLAE----SDEHKRTLIDQL 3843
+ + +M EI L QA+R ++ K K +AHL + Q L + +D+ K +
Sbjct: 1620 MEGDLNEM--EIQLSQANRIASEAQKHLKNSQAHLKDTQLQLDDAVHANDDLKENIAIVE 1677
Query: 3844 ERS---RDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRAR 4014
R+ + EL+ L V E+ E + R+LA + IN+ +
Sbjct: 1678 RRNNLLQAELEELRAVVEQTERS-----RKLAEQELIETSERVQLLHSQNTSL--INQKK 1730
Query: 4015 QLEDEKNALLDEKEEA-EGLRAHLEKEIHAARQGAGEARR-KAEESVNQQLEELRKKNLR 4188
++E + L E EEA + R EK A A A K E+ + LE ++K +
Sbjct: 1731 KMESDLTQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQ 1790
Query: 4189 DVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAE 4368
++ LQ +L+E+E + L+ KK Q+LE ELEN + E QK+ AE
Sbjct: 1791 TIKDLQHRLDEAE---QIALKGGKKQLQKLEARVRELEN------ELEAEQKR----NAE 1837
Query: 4369 ERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISN 4548
++K+ ++ + + + ++ L + VD ++ ++ +R ++ + + +N
Sbjct: 1838 SVKGMRKSERRIKELTYQTEEDKKNLMRLQDLVDKLQLKVK---AYKRQAEEAEEQANTN 1894
Query: 4549 KDDFGKNVHELEKAKRS---LEAELNDMRVQMEEL 4644
F K HEL++A+ E+++N +R + ++
Sbjct: 1895 LSKFRKVQHELDEAEERADIAESQVNKLRAKSRDI 1929
>gi|27764861|ref|NP_002462.1| myosin heavy chain 6; myosin heavy
chain, cardiac muscle alpha isoform [Homo sapiens]
gi|297024|emb|CAA79675.1| cardiac alpha-myosin heavy chain [Homo
sapiens]
Length = 1939
Score = 1134 bits (2934), Expect = 0.0
Identities = 657/1898 (34%), Positives = 1057/1898 (55%), Gaps = 20/1898 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
R C+VPD E F+ I +V+ E + + VT+ D V + NPPKFDKI+DM+
Sbjct: 34 RTECFVPDDKEEFVKAKILSREGGKVIAE-TENGKTVTVKEDQVLQQNPPKFDKIQDMAM 92
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LT+L+E +VL NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PP
Sbjct: 93 LTFLHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPP 152
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAG-ATRNKSLNAAA 612
HIF+I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A R K NA A
Sbjct: 153 HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNANA 212
Query: 613 QQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYIS 792
+ G LE Q++QANP LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++
Sbjct: 213 NK------------GTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLA 260
Query: 793 GANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYL-----LEGVDNYRFLVN 957
A+IE YLLEKSRV+ Q + ER++HIFYQIL + +K E L +Y F+
Sbjct: 261 SADIETYLLEKSRVIFQLKAERNYHIFYQIL----SNKKPELLDMLLVTNNPYDYAFVSQ 316
Query: 958 RGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAML 1137
+++ ++DD +E +T ++ ++GF +E + + ++ A++ GN++F Q+++ +QA
Sbjct: 317 GEVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEP 376
Query: 1138 QDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERL 1317
K +L+GL +L K PR+KVG E+V K Q+ +Q +++ A+AKA YE++
Sbjct: 377 DGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKM 436
Query: 1318 FKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMF 1497
F W+VTRIN +L+ T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF
Sbjct: 437 FNWMVTRINATLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMF 495
Query: 1498 ILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQK 1677
+LEQEEY++EGIEW FIDFG+DLQ IDLIEKPMG++++L+EEC+FPKA D +F KL
Sbjct: 496 VLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLYD 555
Query: 1678 TH-NKHPKFIVP---DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTD 1845
H K F P + ++HF+++HYAG VDY+ WL KN DPLNE VV L Q S+
Sbjct: 556 NHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSL 615
Query: 1846 PFVAGIWKDAEFAGICAAEMNET--AFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPH 2019
+A + F+ A+ ++ + G + + F+TVS LH+E L KLMT LR T PH
Sbjct: 616 KLMATL-----FSSYATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPH 670
Query: 2020 FVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPD 2199
FVRCIIPN K G +++ LV+ QLRCNGVLEGIRICR+GFPNR+ + +FR RY IL P
Sbjct: 671 FVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPV 730
Query: 2200 VIPK-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNF 2376
IP+ FID ++ K++++LDID N Y+ G +KVFF+ G+L LEE RD +L+ +I
Sbjct: 731 AIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRM 790
Query: 2377 QAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDE 2556
QAQ RG L R + N A++ ++NW W +L+ K+KPLL+ T+ E
Sbjct: 791 QAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKE 850
Query: 2557 IRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRL 2736
+ +E KE L K E +E E+K+ ++ E+ +Q Q+Q E +N + ++ +L
Sbjct: 851 MATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQL 910
Query: 2737 QTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDK 2916
+LE V +M +RL +RK + + +K
Sbjct: 911 IKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 970
Query: 2917 TNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLE 3096
+ + L E++ K+K +LE
Sbjct: 971 HATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLE 1030
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
Q+ +LE L +E++ + +LE+ KRKL +L+ +++ + + +L +L K++ ++
Sbjct: 1031 QQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDIN 1090
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
Q ++ ++E A +QK++++ Q I+EL E++E ER AR K E R ++ +LE++
Sbjct: 1091 QQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEI-S 1149
Query: 3457 DVLDKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQI 3633
+ L++ AT +Q M++K E E +R +E+ E + K + V EL +QI
Sbjct: 1150 ERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQI 1209
Query: 3634 EQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESD 3813
+ ++ + +LEK++++ E D+ + + ++A+++K + E E + L E+
Sbjct: 1210 DNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQ 1269
Query: 3814 EHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKI 3993
Q + + E L R EE+E + + R + + K
Sbjct: 1270 RSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKN 1329
Query: 3994 ANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELR 4173
A + + + + L ++ EE +A L++ + A + R K E Q+ EEL
Sbjct: 1330 ALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELE 1389
Query: 4174 KKNLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQK 4344
+ + + LQ E E + + ++K ++Q E+ED +++E A+ +K+Q+
Sbjct: 1390 EAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR 1449
Query: 4345 KFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQ 4524
F+ +AE + +++ + ++ +E R T + L N + EHLE R ++LQ+
Sbjct: 1450 NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQE 1509
Query: 4525 ELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQA 4704
E+ D + GKNVHELEK ++ LE E +++ +EE E +L+ E LR ++
Sbjct: 1510 EISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQ 1569
Query: 4705 LKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQ 4884
+K+E +R ++ KD E E+ +R + + L+ L+ E R ++ + +KK+E + E+E
Sbjct: 1570 IKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEI 1629
Query: 4885 QLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQ 5064
QL ANR+ E + QI+ ++A +A +D+ + +R+ ++AE E+
Sbjct: 1630 QLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEE 1689
Query: 5065 LREANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSN 5235
LR E ++RK Q +K+++E+ + Q
Sbjct: 1690 LRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQE 1749
Query: 5236 CELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSR 5415
C A +K +KA + +L E+ + E K+++E++ +D + ++ E E A
Sbjct: 1750 CRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKG 1809
Query: 5416 ARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKEL 5595
+ Q+ LEA+V+ LE +L E + + + R+ E+R+ + T Q E++K+ + ++L
Sbjct: 1810 GKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDL 1869
Query: 5596 LEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
++K LK + +RQ +EAE++ + +K R VQ E D+
Sbjct: 1870 VDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDE 1907
Score = 152 bits (385), Expect = 7e-35
Identities = 160/820 (19%), Positives = 355/820 (42%), Gaps = 24/820 (2%)
Frame = +1
Query: 3361 ELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKR 3540
E ++M T + + + T + A+ ++++ ++ + E LQ + + + +N +
Sbjct: 846 ETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEE 905
Query: 3541 AIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIA 3720
+Q+ + K + +V+E+++++E ++ ++L ++ + + E +++ ++I
Sbjct: 906 RCDQLI--------KNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDID 957
Query: 3721 LLQASRADIDKKRKIHEAHLMEIQANLAESDE-------HKRTLIDQLERSRDELDHLNR 3879
L+ + A ++K++ E + + +A DE K+ L + +++ D+L +
Sbjct: 958 DLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDL----Q 1013
Query: 3880 VREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEE 4059
V E++ ++ + + +L ++++ R+LE + + +
Sbjct: 1014 VEEDKVNSLSKSKVKLEQQVDDLEGSLEQEK---KVRMDLERAKRKLEGDLKLTQESIMD 1070
Query: 4060 AEGLRAHLEKEIHAARQGAGEARRKAEE--SVNQQLEELRKKNLRDVEHLQKQLEESEVA 4233
E + LE+++ + K E+ ++ QL++ K+N +E L+++LE A
Sbjct: 1071 LENDKLQLEEKLKKKEFDINQQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTA 1130
Query: 4234 KERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAM 4413
+ ++ + + + +ELE+ S LE + + KK E++ + R +++A L +A
Sbjct: 1131 RAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEAT 1190
Query: 4414 SQELRDRETRVLSLLNE-VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKA 4590
+ LR + ++ L E +D ++ ++ ++ + + EL D SN + K LEK
Sbjct: 1191 AAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKV 1250
Query: 4591 KRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRG 4770
R+LE + N+ RV++EE + +L R +L+ N E R + K+ + RG
Sbjct: 1251 SRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTEN----GELARQLEEKEALISQLTRG 1306
Query: 4771 LL---KQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXX 4941
L +Q+ DL+ +LE E + K+ + + L +Q E K E
Sbjct: 1307 KLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKA 1366
Query: 4942 XXXXXEYQIE--------CEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQA 5097
+++ + EE +AK+ +A L++A+ AV A+ L +
Sbjct: 1367 NSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKH----- 1421
Query: 5098 RKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKI-AQXXXXXXXXQSNCELAIDKQRKAQV 5274
R Q R+ + ++K+R KI A+ QS E +Q
Sbjct: 1422 RLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE-------SSQK 1474
Query: 5275 QLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQ 5454
+ ++T+L + +++ ++ +R N++ + +I++L Q
Sbjct: 1475 EARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTE-----------------Q 1517
Query: 5455 YLEDQLNVEGQEKTAANRAARRLEKR--LNDTTQQFEDEKRANEQAKELLEKSNLKNRNL 5628
E NV EK +LE + L + E E+ +A+ LE + +K +
Sbjct: 1518 LGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQ--LEFNQIK-AEI 1574
Query: 5629 RRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
R+L E ++EM + + H+ V LDA + E++
Sbjct: 1575 ERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVL 1614
Score = 129 bits (324), Expect = 9e-28
Identities = 140/753 (18%), Positives = 311/753 (40%), Gaps = 42/753 (5%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + + + +E+ + +R +LE++ QE+ D+ ++ Q + D ++
Sbjct: 848 EKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERC 907
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ L + +E L + + DE L + ++ E A ++
Sbjct: 908 DQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVE 967
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ K A N+ + L +E L +E +K +
Sbjct: 968 KE---------------------KHATENKVKNLTEEMAGL----DEIIAKLTKEKKALQ 1002
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
A Q A + + E+ VN L + + K + V+ L+ LE+ + + + ++K+K++ +L
Sbjct: 1003 EAHQQALDDLQVEEDKVNS-LSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDL 1061
Query: 4279 ---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL 4449
++S M+LEN + + K+ K+F+ ++ ++AL + + ++L++ + R+
Sbjct: 1062 KLTQESIMDLENDKLQLEEKLKK-KEFDINQQNSKIEDEQALALQ--LQKKLKENQARIE 1118
Query: 4450 SLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRV 4629
L E++ + + +++R L +EL++ ++ G + + EAE MR
Sbjct: 1119 ELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRR 1178
Query: 4630 QME----------------------ELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
+E EL + + + + +LE K E D SN +
Sbjct: 1179 DLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNME 1238
Query: 4744 --VEAEEKRRGLLKQIRDLENE----LENEKRGKSGAVSHRKKIENQIGELEQQLEVANR 4905
++A+ + + + D NE LE +R + + R K++ + GEL +QLE
Sbjct: 1239 QIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEA 1298
Query: 4906 LKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA----DRKFRAVEAEREQLRE 5073
L + + + + EE +AK +A L+ A D E E E E
Sbjct: 1299 LISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAE 1358
Query: 5074 ANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAID 5253
L +A + + E K++L ++ + C
Sbjct: 1359 LQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEK 1418
Query: 5254 KQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMA 5433
+ + Q ++E + D+ + ++++ ++ ++K K E +S +S ++ +
Sbjct: 1419 TKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELES-SQKEAR 1477
Query: 5434 ALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNL 5613
+L ++ L++ + R + L++ ++D T+Q + + + +++ ++ +
Sbjct: 1478 SLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEV 1537
Query: 5614 KNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ L+ L+EAE + E K Q E + +
Sbjct: 1538 EKLELQSALEEAEASLEHEEGKILRAQLEFNQI 1570
Score = 96.7 bits (239), Expect = 6e-18
Identities = 110/560 (19%), Positives = 242/560 (42%), Gaps = 27/560 (4%)
Frame = +1
Query: 3046 DHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMG 3225
D +R + +AK +L +L + E+ + S LE+ K +L E+ED +
Sbjct: 1380 DAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNA 1439
Query: 3226 KVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELR---EDMETERNA 3396
L+ + D+ L +Y+E + + QK+ R + T + +L+ E+
Sbjct: 1440 AAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLET 1499
Query: 3397 RNKAEMTRREVVAQLEKVKGDVLDKVDEATML-QDLMSRKDEEVNATKRAIEQIQHTMEG 3573
+ +E ++ L + G+ V E + + L K E +A + A ++H EG
Sbjct: 1500 FKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHE-EG 1558
Query: 3574 KI-------EEQKAKFSRQVEELHDQIEQHKKQRSQ-LEKQQNQADQERADMAQEIALLQ 3729
KI + KA+ R++ E +++EQ K+ + ++ Q D E + + + +
Sbjct: 1559 KILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKK 1618
Query: 3730 ASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFA 3909
D+++ E L AE+ + ++L L+ ++ +LD R ++ + A
Sbjct: 1619 KMEGDLNEM----EIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIA 1674
Query: 3910 NMQRR-------LATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEG 4068
++RR L + I R + L + +L+++K++ E
Sbjct: 1675 IVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMES 1734
Query: 4069 LRAHLEKEIHAARQGAGEARRKAEESVN---QQLEELRKK--NLRDVEHLQKQLEESEVA 4233
L+ E+ A Q A KA++++ EEL+K+ +E ++K +E++
Sbjct: 1735 DLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKD 1794
Query: 4234 KERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAM 4413
+ L ++I L+ +L+ + A R+ E + + + AE ++K+ +
Sbjct: 1795 LQHRLDEAEQI--ALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKEL 1852
Query: 4414 SQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAK 4593
+ + + + +L L + VD ++ ++ +R ++ + + +N F K HEL++A+
Sbjct: 1853 TYQTEEDKKNLLRLQDLVDKLQLKVK---AYKRQAEEAEEQANTNLSKFRKVQHELDEAE 1909
Query: 4594 RS---LEAELNDMRVQMEEL 4644
E+++N +R + ++
Sbjct: 1910 ERADIAESQVNKLRAKSRDI 1929
>gi|3252880|gb|AAC24207.1| myosin heavy chain isoform A [Loligo
pealei]
Length = 1935
Score = 1134 bits (2934), Expect = 0.0
Identities = 660/1927 (34%), Positives = 1052/1927 (54%), Gaps = 19/1927 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
D+++L + R + + AT + +K CWVPD + GF+ I+ DEV V+ T
Sbjct: 9 DMEFLCLTRQKLME-ATSIPFDGKKNCWVPDPDFGFVGAEIQSTKGDEVTVKTDKTQETR 67
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
+ +DD+ + NPPKF+ DM+ LT+LNEAS+LHNL+ RY S IYTYSGLFC+ INPY+
Sbjct: 68 VVKKDDIGQRNPPKFEMNMDMANLTFLNEASILHNLRSRYESGFIYTYSGLFCIAINPYR 127
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
+LPIY++ L+++++GK+R EMPPH+F+IAD AY+ MLQ+RE+QS+L TGESGAGKTENTK
Sbjct: 128 RLPIYTQGLVDKYRGKRRAEMPPHLFSIADNAYQYMLQDRENQSMLITGESGAGKTENTK 187
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVIQY A VA + K ++ +K G LE Q++Q NP+LEA+GN++T +
Sbjct: 188 KVIQYFALVAASLAGKKDKKEEEKKKDEKK------GTLEDQIVQCNPVLEAYGNAETTR 241
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
N+NSSRFGKFIRI+F G I+GA+IE YLLEKSRV Q ER++HIFYQ+L + E
Sbjct: 242 NNNSSRFGKFIRIHFGTQGKIAGADIETYLLEKSRVTYQQSAERNYHIFYQLLSP-AFPE 300
Query: 907 KSEYLLEGVDN--YRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAV 1080
E +L D Y F+ +T+ +DD +E T + ++GF D+E S+ + +
Sbjct: 301 NIEKILAVPDPGLYGFINQGTLTVDGIDDEEEMGLTDTAFDVLGFTDEEKLSMYKCTGCI 360
Query: 1081 LLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQN 1260
L LG +++ Q + +QA +KV LLG+ +L K L+P+IKVG E+V + +N
Sbjct: 361 LHLGEMKWKQ--RGEQAEADGTAEAEKVAFLLGVNAGDLLKCLLKPKIKVGTEYVTQGRN 418
Query: 1261 QEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQ 1440
++Q ++ A+AK+ Y+R+F WLV R+N++LD T + FIG+LDIAGFEIFD NSFEQ
Sbjct: 419 KDQVTNSIAALAKSLYDRMFNWLVRRVNQTLD-TKAKRQFFIGVLDIAGFEIFDFNSFEQ 477
Query: 1441 ICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLD 1620
+CINYTNE+LQQ FN+ MF+LEQEEY++EGI W+FIDFGLDLQ I+LIEKPMG+L++L+
Sbjct: 478 LCINYTNERLQQFFNHHMFVLEQEEYKKEGIVWEFIDFGLDLQACIELIEKPMGILSILE 537
Query: 1621 EECLFPKANDKSFVEKLQKTH-NKHPKFIVPDMR----SKSHFAVVHYAGRVDYSADQWL 1785
EEC+FPKA+D SF KL H K+P F P +++HF + HYAG V YS WL
Sbjct: 538 EECMFPKASDTSFKNKLYDNHLGKNPMFGKPKPPKAGCAEAHFCLHHYAGSVSYSIAGWL 597
Query: 1786 MKNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQL 1965
KN DP+NENVV L+QNS +P V ++ + + + F+T+S +
Sbjct: 598 DKNKDPINENVVELLQNSKEPIVKMLFTPPRI-------LTPGGKKKKGKSAAFQTISSV 650
Query: 1966 HKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFP 2145
HKE L KLM L +T PHFVRCIIPN K G I++ LVL QLRCNGVLEGIRICR+GFP
Sbjct: 651 HKESLNKLMKNLYSTHPHFVRCIIPNELKTPGLIDAALVLHQLRCNGVLEGIRICRKGFP 710
Query: 2146 NRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLA 2325
NR+ + EF+ RY IL P+ +P F DGK K+++AL +D N YR+G +KVFF+ GVL
Sbjct: 711 NRIIYSEFKQRYSILAPNAVPSGFADGKVVTDKVLSALQLDPNEYRLGNTKVFFKAGVLG 770
Query: 2326 HLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWR 2505
LE+ RD +L+ +I FQA RG+L R+ Y N +L LRNW+WWR
Sbjct: 771 MLEDMRDERLSKIISMFQAHIRGYLMRKAYKKLQDQRIGLTLIQRNVRKWLVLRNWEWWR 830
Query: 2506 LFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQL 2685
LF KVKPLL + R +DE + +E KE E +E E++ ++ ++ + +
Sbjct: 831 LFNKVKPLLNIARQEDENKKAQEEFAKMKEEFASCEQMRKELEEQNTVLMQQKNDLVIAM 890
Query: 2686 QQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXX 2865
+ + ++ +L + + E + ++ D+L ++K + +
Sbjct: 891 SSGEDAIGDAEEKIEQLIKQKSDFETQIKELEDKLMDEEDAATELSAQKKKSDAEIGELK 950
Query: 2866 XXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLL 3045
+KT D + L
Sbjct: 951 KDVEDLEAGLAKAEQEKTTKDNQIKTLQDEMAQQDEHLSKLNKEKKNLEEVQKKTLEDLQ 1010
Query: 3046 DHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMG 3225
E++ H K K +LE L ELE +L RE++ ++++ KRK+ +L+ +++ + +
Sbjct: 1011 AEEDKVNHLSKLKTKLEQTLDELEDNLEREKKIPGDVDKAKRKVEQDLKTTQETVEDLER 1070
Query: 3226 KVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNK 3405
+L + K+D E+ ++ ++E V +QK+++++Q I+EL E++E ER AR K
Sbjct: 1071 VKRDLEDAGRKKDMEINGLNSKLEDEQNLVAQLQKKIKELQARIEELEEELEAERQARTK 1130
Query: 3406 AEMTRREVVAQLEKVKGDVLDKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIE 3582
E R E+ +LE++ G+ LD+ AT Q +L ++++E+ +R +E+ E +I
Sbjct: 1131 VEKQRTELSRELEEL-GERLDEAGGATAAQMELNKKREQELLRLRRDLEEATMQHESQIA 1189
Query: 3583 EQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRK 3762
+ K EL DQI+Q +K +S+LEK++ Q E D+ ++ +R +K K
Sbjct: 1190 TLRKKNQEATNELGDQIDQLQKVKSRLEKEKTQLRAEMDDVQSQVEHAGKNRGCSEKMSK 1249
Query: 3763 IHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXX 3942
EA L E+ A + + L Q R + E L R EE EH + + ++
Sbjct: 1250 QMEAQLSELNAKIDDQARSVSELTSQKSRLQTEAADLTRQLEEAEHNVGQLTKLKSSLGA 1309
Query: 3943 XXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGE 4122
RL+ R L + + + + EE ++ L++ + A +
Sbjct: 1310 SLEDAKRSLEDEGRLRAKLQAEVRNLNSDIDGIRESLEEEAESKSDLQRALSRANAEVQQ 1369
Query: 4123 ARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKER-------ILQSKKKIQQELE 4281
R K E + +EL + LQ +L E+E + + ++K ++Q ELE
Sbjct: 1370 WRSKFESEGAARADELEDAKRK----LQAKLSEAEQTADTLHSKCAGLEKAKSRLQGELE 1425
Query: 4282 DSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLN 4461
D ++++E A + EK+Q+ F+ ++E + + + +E R + +
Sbjct: 1426 DLAIDVERSSAHANNLEKKQRNFDKVVSEWQHKCNDLQAELENAQKEARSYSAELFRVRA 1485
Query: 4462 EVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE 4641
+ + + + + R ++L E+ D + G+N HELEKA++ L E +++ +EE
Sbjct: 1486 QCEEVGDTVASLRRENKNLADEIHDLTDQLGEGGRNTHELEKARKHLALEKEELQAALEE 1545
Query: 4642 LEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKR 4821
E L+ E +R + ++ E DR + K+ E + RR + I ++ LE E +
Sbjct: 1546 AEGALEQEEAKVMRATLEISQIRQEIDRRLQEKEEEFDNTRRNHQRAIESMQASLEAEAK 1605
Query: 4822 GKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKED 5001
GK+ A+ +KK+E I ELE L+ NR K E E Q + EE + +++
Sbjct: 1606 GKAEALRIKKKLEGDINELEIALDATNRGKAELEKNVKKYQGQIRELQSQVEEEQAQRDE 1665
Query: 5002 IAALLREADRKFRAVEAEREQLREANEGLMQARK----QXXXXXXXXXXXRAKGGGISSE 5169
+ A+R+ A+ E E+LR E +ARK + +A+ + S
Sbjct: 1666 AKEHYQMAERRCAAINGELEELRTILEQAERARKAAENELADASDRVNELQAQVSTVGS- 1724
Query: 5170 EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQS 5349
+KR+LE + + + A ++ + A ++ +L E+ E ++S
Sbjct: 1725 QKRKLEGDVTAMQSDLDELNNELKDADERAKHAMADATRLADELRQEQDHGLSVEKMRKS 1784
Query: 5350 LERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEK 5529
LE ++ + ++ E E+ A + + LE++V+ LE +L+ E + ++ R++++
Sbjct: 1785 LESQVKELQVRLDESEAAALKGGKKMIQKLESRVRELEAELDSEQRRHAETQKSMRKVDR 1844
Query: 5530 RLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
R+ + + Q E++++ E+ +EL++K K + +RQ++EAE+ + K R VQ+E +D
Sbjct: 1845 RVKELSFQQEEDRKNYERMQELVDKLQNKIKTYKRQVEEAEEIAAINLAKFRKVQQELED 1904
Query: 5710 LLDANEQ 5730
+ +Q
Sbjct: 1905 AEERADQ 1911
Score = 181 bits (460), Expect = 1e-43
Identities = 175/917 (19%), Positives = 385/917 (41%), Gaps = 19/917 (2%)
Frame = +1
Query: 3052 EERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKV 3231
E+ K + +++ + EQ + + L Q K L+ + +D + + K+
Sbjct: 845 EDENKKAQEEFAKMKEEFASCEQMRKELEEQNTVLMQQKNDLVIAMSSGEDAIGDAEEKI 904
Query: 3232 EELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
E+L Q + +++ + +E T + Q + I EL++D+E
Sbjct: 905 EQLIKQKSDFETQIKELEDKLMDEEDAATELSAQKKKSDAEIGELKKDVE---------- 954
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDE---EVNATKRAIEQIQH-TMEGKI 3579
++ A L K + + K ++ LQD M+++DE ++N K+ +E++Q T+E
Sbjct: 955 ----DLEAGLAKAEQEKTTKDNQIKTLQDEMAQQDEHLSKLNKEKKNLEEVQKKTLEDLQ 1010
Query: 3580 EEQ---------KAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQA 3732
E+ K K + ++EL D +E+ KK ++K + + +Q+ + + L+
Sbjct: 1011 AEEDKVNHLSKLKTKLEQTLDELEDNLEREKKIPGDVDKAKRKVEQDLKTTQETVEDLER 1070
Query: 3733 SRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFAN 3912
+ D++ + + + + + L E ++ L+ QL++ EL R+ E EE A
Sbjct: 1071 VKRDLEDAGRKKDMEINGLNSKL----EDEQNLVAQLQKKIKELQA--RIEELEEELEAE 1124
Query: 3913 MQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKE 4092
Q R T+++ +R+LE E LDE A + L K+
Sbjct: 1125 RQAR------------------TKVEKQRTELSRELE-ELGERLDEAGGATAAQMELNKK 1165
Query: 4093 IHAARQGAGEARRKAEESVNQ---QLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKK 4263
Q RR EE+ Q Q+ LRKKN L Q+++ + K R+ + K +
Sbjct: 1166 ---REQELLRLRRDLEEATMQHESQIATLRKKNQEATNELGDQIDQLQKVKSRLEKEKTQ 1222
Query: 4264 IQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETR 4443
++ E++D ++E+ + SEK K+ E+Q++E + ++ + +T
Sbjct: 1223 LRAEMDDVQSQVEHAGKNRGCSEKMSKQMEAQLSELNAKIDDQARSVSELTSQKSRLQTE 1282
Query: 4444 VLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDM 4623
L +++ + ++ + +++ SL L+D+ + +D G+ +L+ R+L ++++ +
Sbjct: 1283 AADLTRQLEEAEHNVGQLTKLKSSLGASLEDAKRSLEDEGRLRAKLQAEVRNLNSDIDGI 1342
Query: 4624 RVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENE 4803
R +EE ++ + A R Q +S+ + + + E E+ +R L ++ + E
Sbjct: 1343 RESLEEEAESKSDLQRALSRANAEVQQWRSKFESEGAARADELEDAKRKLQAKLSEAEQT 1402
Query: 4804 LENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEA 4983
+ +G + +++ ++ +L +E ++ E+Q +C +
Sbjct: 1403 ADTLHSKCAGLEKAKSRLQGELEDLAIDVERSSAHANNLEKKQRNFDKVVSEWQHKCNDL 1462
Query: 4984 RQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGIS 5163
+ E+ R + V A+ E++ + L + K +GG +
Sbjct: 1463 QAELENAQKEARSYSAELFRVRAQCEEVGDTVASLRRENKNLADEIHDLTDQLGEGGRNT 1522
Query: 5164 SE-EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAE 5340
E EK R + + ++ L ++ + + LE ++R L +K E
Sbjct: 1523 HELEKARKHLALEKEELQAALEEAEGALEQEEAKVMRATLEISQIRQEIDRRLQEKEEEF 1582
Query: 5341 KQSLERSNRDYKAKITELESGAQSRARAQMAA--LEAKVQYLEDQLNVEGQEKTAANRAA 5514
+ R ++ LE+ A+ +A A LE + LE L+ + K +
Sbjct: 1583 DNTRRNHQRAIESMQASLEAEAKGKAEALRIKKKLEGDINELEIALDATNRGKAELEKNV 1642
Query: 5515 RRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQ 5694
++ + ++ + Q E+E+ ++AKE + + + + +L+E + + + +
Sbjct: 1643 KKYQGQIRELQSQVEEEQAQRDEAKEHYQMAERRCAAINGELEELRTILEQAERARKAAE 1702
Query: 5695 READDLLDANEQLTREL 5745
E D D +L ++
Sbjct: 1703 NELADASDRVNELQAQV 1719
Score = 109 bits (273), Expect = 7e-22
Identities = 113/538 (21%), Positives = 235/538 (43%), Gaps = 30/538 (5%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLM 3255
KAK RL+ +L +L D+ R + + LE+ +R + + + + ++E +
Sbjct: 1415 KAKSRLQGELEDLAIDVERSSAHANNLEKKQRNFDKVVSEWQHKCNDLQAELENAQKEAR 1474
Query: 3256 KRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDM-ETERN------ARNKAEM 3414
EL + +E V ++++ +++ I +L + + E RN AR +
Sbjct: 1475 SYSAELFRVRAQCEEVGDTVASLRRENKNLADEIHDLTDQLGEGGRNTHELEKARKHLAL 1534
Query: 3415 TRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKA 3594
+ E+ A LE+ +G + + +EA +++ + E++ ++ I++ E + + +
Sbjct: 1535 EKEELQAALEEAEGAL--EQEEAKVMRATL-----EISQIRQEIDRRLQEKEEEFDNTRR 1587
Query: 3595 KFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEA 3774
R +E + +E K +++ + + + + + ++ + +A+++K K ++
Sbjct: 1588 NHQRAIESMQASLEAEAKGKAEALRIKKKLEGDINELEIALDATNRGKAELEKNVKKYQG 1647
Query: 3775 HLMEIQANLAESD-------EHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLAT 3933
+ E+Q+ + E EH + + EL+ L + E+ E A + LA
Sbjct: 1648 QIRELQSQVEEEQAQRDEAKEHYQMAERRCAAINGELEELRTILEQAERARKAAENELAD 1707
Query: 3934 AXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQG 4113
A K R+LE + A+ + +E L L+ A+
Sbjct: 1708 ASDRVNELQAQVSTVGSQK-------RKLEGDVTAMQSDLDE---LNNELKDADERAKHA 1757
Query: 4114 AGEARRKAEESVNQQ-----LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
+A R A+E +Q +E++RK V+ LQ +L+ESE A L+ KK+ Q+L
Sbjct: 1758 MADATRLADELRQEQDHGLSVEKMRKSLESQVKELQVRLDESEAAA---LKGGKKMIQKL 1814
Query: 4279 EDSSMELE----NVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRV 4446
E ELE + + H +++K +K + ++ E ++ + + M QEL D+
Sbjct: 1815 ESRVRELEAELDSEQRRHAETQKSMRKVDRRVKELSFQQEEDRKNYERM-QELVDK---- 1869
Query: 4447 LSLLNEVDIMKEHLEESDRVR-------RSLQQELQDSISNKDDFGKNVHELEKAKRS 4599
L N++ K +EE++ + R +QQEL+D+ D + +L RS
Sbjct: 1870 --LQNKIKTYKRQVEEAEEIAAINLAKFRKVQQELEDAEERADQSEGALQKLRAKNRS 1925
>gi|50838836|ref|NP_001001302.1| chick atrial myosin heavy chain
[Gallus gallus]
gi|14017756|dbj|BAB47399.1| chick atrial myosin heavy chain [Gallus
gallus]
Length = 1931
Score = 1134 bits (2933), Expect = 0.0
Identities = 654/1901 (34%), Positives = 1055/1901 (55%), Gaps = 14/1901 (0%)
Frame = +1
Query: 49 PATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPK 228
P A R LC+VP F+ + + V V + +T+ DV NPPK
Sbjct: 18 PRPTPAGDTRGLCFVPHPQLEFIRARVTARAGNGVTVT-TEMGETLTVPEADVHPQNPPK 76
Query: 229 FDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFK 408
FD+IEDM+ LT+L+E +VL+NLK+RY S +IYTYSGLFCV +NPYK LP+Y+ +++ ++
Sbjct: 77 FDRIEDMAMLTFLHEPAVLYNLKERYASWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYR 136
Query: 409 GKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATR 588
GKKR E+PPHIF+I+D AY++ML +RE+QSIL TGESGAGKT NTK+VIQY A +A
Sbjct: 137 GKKRTEVPPHIFSISDNAYQNMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGH 196
Query: 589 NKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRIN 768
K K + G LE Q++QANP LEAFGN+KTV+NDNSSRFGKFIRI+
Sbjct: 197 RK------------KEVANSSKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIH 244
Query: 769 FDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLL--EGVDNY 942
F +G ++ A+IE YLLEKSRV+ Q + ER++HIFYQIL E E LL +Y
Sbjct: 245 FGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSN-KKPELLEMLLITNNPYDY 303
Query: 943 RFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKS 1122
++ +T+ ++DD +E +T ++ ++GF +E + + ++ A++ GN++F Q+++
Sbjct: 304 SYVSQGEVTVASIDDSEELLATDSAFDVLGFTAEEKAGVYKLTGAIMHFGNMKFKQKQRE 363
Query: 1123 DQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKA 1302
+QA K +L+GL +L K PR+KVG E+V K Q+ +Q +++ A+AKA
Sbjct: 364 EQAEPDGTEDCDKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKA 423
Query: 1303 SYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLF 1482
YE++F W+V RIN SL+ T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ F
Sbjct: 424 VYEKMFNWMVVRINNSLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFF 482
Query: 1483 NNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFV 1662
N+ MF+LEQEEY++EGIEW+FIDFG+DLQ IDLIEKPMG++++L+EEC+FPKA+D +F
Sbjct: 483 NHHMFVLEQEEYKKEGIEWEFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKASDMTFK 542
Query: 1663 EKLQKTH-NKHPKFIVP---DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLM 1830
KL H K F P +S++HF+++HYAG VDY+ WL KN DPLNE VVGL
Sbjct: 543 AKLFDNHLGKSANFGKPRNVKGKSEAHFSLIHYAGTVDYNIIGWLEKNKDPLNETVVGLY 602
Query: 1831 QNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNT 2010
Q S +A ++ + +AG A G + + F+TVS LH+E L KLM L+ T
Sbjct: 603 QKSALKLLASLF--SNYAGADAGGDGGKGKGAKKKGSSFQTVSALHRENLNKLMANLKTT 660
Query: 2011 SPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEIL 2190
PHFVRC+IPN K+ G +++ LV+ QLRCNGVLEGIRICR+GFPNR+ + +FR RY I
Sbjct: 661 HPHFVRCLIPNERKEPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRIP 720
Query: 2191 TPDVIPK-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALI 2367
P IP+ FID ++ K++ +LDID N Y+ G +KVFF+ G+L LEE RD +L+ +I
Sbjct: 721 NPTAIPEGQFIDSRKGAEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSLII 780
Query: 2368 MNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRT 2547
QAQ RG L R + N A++ ++NW W +L+ K+KPLL+ T
Sbjct: 781 TRIQAQARGQLMRIEFKKILERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAET 840
Query: 2548 DDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIR 2727
+ E++ +E KE L K +E E+K+ ++ E+ +Q Q+Q E +N A+ ++
Sbjct: 841 EKEMQTMKEEFGHLKEALEKSAARRKELEEKMVSMLQEKNDLQLQVQAEQDNLADAEERC 900
Query: 2728 GRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXX 2907
+L +LE V +M +RL +RK + +
Sbjct: 901 DQLIKNKIQLEAKVKEMTERLEEEEEMNAELAAKKRKLEDECSELKKDIDDLELSLAKVE 960
Query: 2908 XDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKG 3087
+K + + L E++ KAKG
Sbjct: 961 KEKHATENKVKNLTEEMAGLDENITKLTKEKKILQESHQQALDDLQAEEDKVNTLAKAKG 1020
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDE 3267
+LE Q+ +LE L +E++ + +LE+ KRKL +L+ +++ + + ++L +L K+D
Sbjct: 1021 KLEQQVDDLESSLEQEKKIRMDLERAKRKLEGDLKLAQESIMDLENDKQQLEERLKKKDF 1080
Query: 3268 ELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEK 3447
EL R ++E A +QK+++++Q I+EL E++E ER R K E R E++ +LE+
Sbjct: 1081 ELNTLNARIEDEQAISAQLQKKLKELQARIEELEEELEAERTGRAKVEKLRSELLQELEE 1140
Query: 3448 VKGDVLDKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELH 3624
+ L++ AT +Q +L +++ E +R +E+ E + K + V EL
Sbjct: 1141 T-SERLEEAGGATSVQLELNKKREAEFQKLRRDLEEATLQHEATAATLRKKHADSVAELS 1199
Query: 3625 DQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLA 3804
+Q++ ++ + +LEK++++ E D+ L ++ +++K + E + E ++ L
Sbjct: 1200 EQLDNLQRVKQKLEKEKSELKLELDDVNSNTEQLIKAKTNLEKMCRTTEDQMNEHRSKLE 1259
Query: 3805 ESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTR 3984
E+ L Q + + E L+R EE+E + R T +
Sbjct: 1260 EAQRTVTDLSTQRAKLQTENSELSRQLEEKEAFINQLTRGKLTYTQQLEDLKRQLEEEAK 1319
Query: 3985 LKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLE 4164
K A + + + + + L ++ EE +A L++ + A + R K E Q+ E
Sbjct: 1320 AKNALAHALQSAQHDCDLLREQYEEEMEAKAELQRALSKANSEVAQWRTKYETDAIQRTE 1379
Query: 4165 ELRKKNLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEK 4335
EL + + + LQ+ E E + + ++K ++Q E+ED ++E A+ +K
Sbjct: 1380 ELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMADVERSNAAAAALDK 1439
Query: 4336 RQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRS 4515
+Q+ F+ ++E + +++ + +A +E R T + L N + EHLE R ++
Sbjct: 1440 KQRNFDKILSEWKQKFEESQTELEASQKEARSLSTELFKLKNAYEESLEHLETFKRENKN 1499
Query: 4516 LQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVT 4695
LQ+E+ D K++HELEK ++ L+AE +++ +EE E +L+ E LR ++
Sbjct: 1500 LQEEILDLTEQLGASQKSIHELEKVRKQLDAEKLELQAALEEAEASLEHEEGKILRAQLE 1559
Query: 4696 NQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGE 4875
+K++ +R ++ KD E E+ +R L+ + L+ L+ E R ++ A+ +KK+E + E
Sbjct: 1560 FNQVKADYERKLAEKDEEIEQSKRNHLRVVDSLQTSLDAETRSRNEALRLKKKMEGDLNE 1619
Query: 4876 LEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAE 5055
+E QL ANR E + Q++ ++ +A ED+ + +R+ +++E
Sbjct: 1620 MEIQLSHANRTAAEAQKQVKALQGYLKDTQLQLDDVVRANEDLKENIAIVERRNNLLQSE 1679
Query: 5056 REQLREANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXX 5226
E+LR E +ARK Q +K+++EA I+Q
Sbjct: 1680 LEELRAMVEQSERARKLAEQELIEASERVQLLHSQNTSLINQKKKMEADISQLQTEVEEA 1739
Query: 5227 QSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGA 5406
C A +K +KA + +L E+ + E K+++E++ +D + ++ E E A
Sbjct: 1740 IQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLA 1799
Query: 5407 QSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQA 5586
+ Q+ LE +V+ LE++L E + + + R+ E+R+ + + Q E++++ +
Sbjct: 1800 LKGGKKQLQKLEVRVRELENELEAEQKRNAESIKGLRKSERRVKELSYQTEEDRKNMVRL 1859
Query: 5587 KELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
++L++K LK + +RQ +EAE++ + K R VQ E D+
Sbjct: 1860 QDLVDKLQLKVKAYKRQAEEAEEQANSNLAKFRKVQHELDE 1900
Score = 155 bits (391), Expect = 1e-35
Identities = 175/861 (20%), Positives = 360/861 (41%), Gaps = 54/861 (6%)
Frame = +1
Query: 3325 QKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLM 3504
+K+M+ M+ L+E +E R + E ++V+ L++ L E L D
Sbjct: 841 EKEMQTMKEEFGHLKEALEKSAARRKELE---EKMVSMLQEKNDLQLQVQAEQDNLADAE 897
Query: 3505 SRKDEEVN-------ATKRAIEQIQHT--MEGKIEEQKAKFSRQVEELHDQIEQHKKQRS 3657
R D+ + K E+++ M ++ +K K + EL I+ + +
Sbjct: 898 ERCDQLIKNKIQLEAKVKEMTERLEEEEEMNAELAAKKRKLEDECSELKKDIDDLELSLA 957
Query: 3658 QLEKQQNQADQERADMAQEIALLQASRADIDKKRKI-HEAHLMEIQANLAESDEHKRTLI 3834
++EK+++ + + ++ +E+A L + + K++KI E+H + AE D+ TL
Sbjct: 958 KVEKEKHATENKVKNLTEEMAGLDENITKLTKEKKILQESHQQALDDLQAEEDK-VNTLA 1016
Query: 3835 DQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRAR 4014
+ ++D L E+E+ +++R A
Sbjct: 1017 KAKGKLEQQVDDLESSLEQEKKIRMDLER------------------------AKRKLEG 1052
Query: 4015 QLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDV 4194
L+ + +++D + + + L L+K+ AR + E++++ QL++ K+ +
Sbjct: 1053 DLKLAQESIMDLENDKQQLEERLKKKDFELN--TLNARIEDEQAISAQLQKKLKELQARI 1110
Query: 4195 EHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEER 4374
E L+++LE + ++ + + ++ QELE++S LE + + KK E++ + R
Sbjct: 1111 EELEEELEAERTGRAKVEKLRSELLQELEETSERLEEAGGATSVQLELNKKREAEFQKLR 1170
Query: 4375 VAVQKALLDRDAMSQELRDRET-RVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNK 4551
+++A L +A + LR + V L ++D ++ ++ ++ + L+ EL D SN
Sbjct: 1171 RDLEEATLQHEATAATLRKKHADSVAELSEQLDNLQRVKQKLEKEKSELKLELDDVNSNT 1230
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAI 4731
+ K LEK R+ E ++N+ R ++EE + + R +L+ N SE R +
Sbjct: 1231 EQLIKAKTNLEKMCRTTEDQMNEHRSKLEEAQRTVTDLSTQRAKLQTEN----SELSRQL 1286
Query: 4732 SNKDVEAEEKRRGLL---KQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVAN 4902
K+ + RG L +Q+ DL+ +LE E + K+ + ++ L +Q E
Sbjct: 1287 EEKEAFINQLTRGKLTYTQQLEDLKRQLEEEAKAKNALAHALQSAQHDCDLLREQYEEEM 1346
Query: 4903 RLKEEYXXXXXXXXXXXXEYQIE--------CEEARQAKEDIAALLREADRKFRAVEAE- 5055
K E +++ + EE +AK+ +A L+EA+ AV A+
Sbjct: 1347 EAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKC 1406
Query: 5056 ------REQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXX 5217
+ +L+ E LM ++ + I SE K++ E +
Sbjct: 1407 SSLEKTKHRLQNEIEDLMADVERSNAAAAALDKKQRNFDKILSEWKQKFEESQTELEASQ 1466
Query: 5218 XXXQSNCELAIDKQRKAQVQLEQITT-------------DLSMERTLNQKT----EAEKQ 5346
+S + + LE + T DL+ + +QK+ E ++
Sbjct: 1467 KEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEILDLTEQLGASQKSIHELEKVRK 1526
Query: 5347 SLERSNRDYKAKITELESGAQSRA----RAQMAALEAKVQY----LEDQLNVEGQEKTAA 5502
L+ + +A + E E+ + RAQ+ + K Y E +E Q K
Sbjct: 1527 QLDAEKLELQAALEEAEASLEHEEGKILRAQLEFNQVKADYERKLAEKDEEIE-QSKRNH 1585
Query: 5503 NRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKH 5682
R L+ L+ T+ + R ++ + L + ++ + R EA+ ++ +
Sbjct: 1586 LRVVDSLQTSLDAETRSRNEALRLKKKMEGDLNEMEIQLSHANRTAAEAQKQVKALQGYL 1645
Query: 5683 RNVQREADDLLDANEQLTREL 5745
++ Q + DD++ ANE L +
Sbjct: 1646 KDTQLQLDDVVRANEDLKENI 1666
Score = 73.9 bits (180), Expect = 4e-11
Identities = 105/500 (21%), Positives = 204/500 (40%), Gaps = 59/500 (11%)
Frame = +1
Query: 4429 DRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVH----------- 4575
+ E + ++ E +KE LE+S R+ L++++ + K+D V
Sbjct: 839 ETEKEMQTMKEEFGHLKEALEKSAARRKELEEKMVSMLQEKNDLQLQVQAEQDNLADAEE 898
Query: 4576 ---ELEKAKRSLEAELNDMRVQMEELED-NLQIAEDARLRLEVTNQALKSESD------- 4722
+L K K LEA++ +M ++EE E+ N ++A R +LE LK + D
Sbjct: 899 RCDQLIKNKIQLEAKVKEMTERLEEEEEMNAELAAKKR-KLEDECSELKKDIDDLELSLA 957
Query: 4723 ------RAISNKDVEAEEKRRGLLKQIRDLENE--------------LENEKRGKSGAVS 4842
A NK E+ GL + I L E L+ E+ +
Sbjct: 958 KVEKEKHATENKVKNLTEEMAGLDENITKLTKEKKILQESHQQALDDLQAEEDKVNTLAK 1017
Query: 4843 HRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLRE 5022
+ K+E Q+ +LE LE +++ + Q + K+ + L++
Sbjct: 1018 AKGKLEQQVDDLESSLEQEKKIRMDLERAKRKLEGDLKLAQESIMDLENDKQQLEERLKK 1077
Query: 5023 ADRKFRAVEAERE-------QLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRR 5181
D + + A E QL++ + L ++ RAK + SE +
Sbjct: 1078 KDFELNTLNARIEDEQAISAQLQKKLKELQARIEELEEELEAERTGRAKVEKLRSELLQE 1137
Query: 5182 LEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERS 5361
LE ++ +L ++K+R+A+ Q ++ DL E TL EA +L +
Sbjct: 1138 LEE--TSERLEEAGGATSVQLELNKKREAEFQ--KLRRDLE-EATLQH--EATAATLRKK 1190
Query: 5362 NRDYKAKITE-LESGAQSRARAQMAALEAKVQYLEDQLNVEG--QEKTAANRAARRLEKR 5532
+ D A+++E L++ + + + + E K++ + N E + KT + R E +
Sbjct: 1191 HADSVAELSEQLDNLQRVKQKLEKEKSELKLELDDVNSNTEQLIKAKTNLEKMCRTTEDQ 1250
Query: 5533 LNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAE---DEMSRERTKH----RNV 5691
+N+ + E+ +R K +N L RQL+E E ++++R + + ++
Sbjct: 1251 MNEHRSKLEEAQRTVTDLSTQRAKLQTENSELSRQLEEKEAFINQLTRGKLTYTQQLEDL 1310
Query: 5692 QREADDLLDANEQLTRELMN 5751
+R+ ++ A L L +
Sbjct: 1311 KRQLEEEAKAKNALAHALQS 1330
>gi|38091410|ref|XP_354614.1| myosin, heavy polypeptide 3, skeletal
muscle, embryonic [Mus musculus]
Length = 1940
Score = 1133 bits (2931), Expect = 0.0
Identities = 660/1890 (34%), Positives = 1052/1890 (54%), Gaps = 15/1890 (0%)
Frame = +1
Query: 85 CWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTY 264
C+V D E ++ G IK + +V VE D SR + + +DV NPPKFDKIEDM+ LT+
Sbjct: 38 CFVVDSKEEYVKGKIKSSQDGKVTVETED-SRTLVVKPEDVYAMNPPKFDKIEDMAMLTH 96
Query: 265 LNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIF 444
LNE +VL+NLKDRY S +IYTYSGLFCV +NPYK LP+Y+ ++++ ++GKKR E PPHIF
Sbjct: 97 LNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVDGYRGKKRQEAPPHIF 156
Query: 445 AIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNI 624
+I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A + AA ++
Sbjct: 157 SISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATI-----------AATGDL 205
Query: 625 VQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANI 804
+K D + G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+I
Sbjct: 206 AKKKDSKMK-GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADI 264
Query: 805 EFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPN 978
E YLLEKSRV Q + ERS+HIFYQIL E E LL + +Y F+ I + +
Sbjct: 265 ETYLLEKSRVTFQLKAERSYHIFYQILSN-KKPELIELLLITTNPYDYPFISQGEILVAS 323
Query: 979 VDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQ 1158
+DD +E +T +++ I+GF +E S + ++ AV+ GN++F Q+++ +QA V
Sbjct: 324 IDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVAD 383
Query: 1159 KVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTR 1338
K +L+GL +L KA PR+KVG E+V K Q +Q AV A++K+ YE+LF W+VTR
Sbjct: 384 KTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTR 443
Query: 1339 INKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEY 1518
IN+ LD T FIG+LDIAGFEIF+ NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY
Sbjct: 444 INQQLD-TKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 502
Query: 1519 QREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH----N 1686
++EGIEW FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H N
Sbjct: 503 KKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSN 562
Query: 1687 KHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIW 1866
K V ++++HF++VHYAG VDYS WL KN DPLNE VVGL Q S++ +A +
Sbjct: 563 NFQKPKVVKGKAEAHFSLVHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHL- 621
Query: 1867 KDAEFAGICAAEMNETAFGMRSRKG-MFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPN 2043
+A + + + +KG F+TVS L +E L KLM+ LR T PHFVRCIIPN
Sbjct: 622 ----YATFATTDADGGKKKVAKKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPN 677
Query: 2044 HEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFI 2220
K G + +LVL QLRCNGVLEGIRICR+GFPNR+ + +F+ RY +L IP+ FI
Sbjct: 678 ETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFI 737
Query: 2221 DGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFL 2400
D K++ K++ ++DID Y+ G +KVFF+ G+L LEE RD +L LI QA CRGFL
Sbjct: 738 DSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDERLAKLITRTQAVCRGFL 797
Query: 2401 SRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDEL 2580
R + N A++ +++W W +LF K+KPLL+ T+ E+ +E
Sbjct: 798 MRVEFQKMMQRRESIFCIQYNIRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEF 857
Query: 2581 RATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELE 2760
+ TK+ L K E +E E+KL ++ E+ +Q Q+Q ESEN + ++ +L +LE
Sbjct: 858 QKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLE 917
Query: 2761 YIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXX 2940
+ ++ +R +RK + + +K +
Sbjct: 918 AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 977
Query: 2941 XXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQ 3120
+ L E++ K K +LE Q+ +LE
Sbjct: 978 NLTEELAGLDETIAKLTREKKALQEAHQQTLDDLQAEEDKVNSLSKLKSKLEQQVDDLES 1037
Query: 3121 DLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDE 3300
L +E++ + +LE++KRKL +L+ +++ + + ++L+ +L K+D E ++ ++
Sbjct: 1038 SLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYSQLQSKVED 1097
Query: 3301 ESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDE 3480
E +QK+++++Q I+EL E++E ER R K E R + +LE++ + L++
Sbjct: 1098 EQTLSLQLQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEEL-SERLEEAGG 1156
Query: 3481 ATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRS 3657
T Q +L +++ E +R +E+ E + + K + EL +QI+ ++ +
Sbjct: 1157 VTSTQIELNKKREAEFLKLRRDLEEATLQHEATVATLRKKHADSAAELAEQIDNLQRVKQ 1216
Query: 3658 QLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLID 3837
+LEK++++ E D++ + + S+A+++K + E L E + E L
Sbjct: 1217 KLEKEKSEFKLEIDDLSSSVESVSKSKANLEKICRTLEDQLSEARGKNEEMQRSLSELTT 1276
Query: 3838 QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQ 4017
Q R + E L+R EE+E + + R + K A + +
Sbjct: 1277 QKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQIEELKRQLEEENKAKNALAHALQS 1336
Query: 4018 LEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVE 4197
+ + L ++ EE + +A L++ + A + R K E Q+ EEL + + +
Sbjct: 1337 SRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQ 1396
Query: 4198 HLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAE 4368
LQ E+ E + + ++K+++Q E+ED +++E + +K+Q+ F+ +AE
Sbjct: 1397 RLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAE 1456
Query: 4369 ERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISN 4548
+ +++ + +A +E R T + L N + + LE R ++L+QE+ D
Sbjct: 1457 WKTKCEESQAELEAALKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQ 1516
Query: 4549 KDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRA 4728
+ GK++HELEK+++ +E E D+++ +EE E L+ E LR+++ +KSE DR
Sbjct: 1517 IAENGKSIHELEKSRKQMELEKADIQMALEEAEAALEHEEAKILRIQLELTQVKSEIDRK 1576
Query: 4729 ISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRL 4908
I+ KD E E+ +R + + ++ L+ E R ++ A+ +KK+E + E+E QL ANR
Sbjct: 1577 IAEKDEEIEQLKRNYQRTVETMQGALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQ 1636
Query: 4909 KEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGL 5088
E + Q+ ++A + +ED+ L +R+ ++AE E+LR E
Sbjct: 1637 AAETIKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQT 1696
Query: 5089 MQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQ 5259
+ARK Q K++LE + Q + A +K
Sbjct: 1697 ERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLTQLQSEVEDACRDARNAEEKA 1756
Query: 5260 RKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAAL 5439
+KA + +L E+ + E K++LE++ +D + ++ E E A + Q+ L
Sbjct: 1757 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1816
Query: 5440 EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKN 5619
E +++ LE +L E + T + + R+ E+R+ + T Q E++++ + ++L++K +K
Sbjct: 1817 ETRIRELEFELEGEQKRNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKV 1876
Query: 5620 RNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
++ +RQ +EA+++ + TK R Q E ++
Sbjct: 1877 KSYKRQAEEADEQANAHLTKFRKAQHELEE 1906
Score = 77.0 bits (188), Expect = 5e-12
Identities = 103/526 (19%), Positives = 212/526 (39%), Gaps = 22/526 (4%)
Frame = +1
Query: 4234 KERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAM 4413
K + L + ++E+ E + + SE ++K+ E ++ L A
Sbjct: 836 KIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAE 895
Query: 4414 SQELRDRETRVLSLLN-------EVDIMKEHLEESDRV-------RRSLQQELQDSISNK 4551
S+ L D E R L+ ++ + E E+ + + +R L+ E + +
Sbjct: 896 SENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 955
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQA----LKSES 4719
DD + ++EK K + E ++ ++ ++ L++ + + L+ +Q L++E
Sbjct: 956 DDLELTLAKVEKEKHATENKVKNLTEELAGLDETIAKLTREKKALQEAHQQTLDDLQAEE 1015
Query: 4720 DRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
D+ S ++++ L +Q+ DLE+ LE EK+ + +++K+E G+L+ E
Sbjct: 1016 DKVNSLSKLKSK-----LEQQVDDLESSLEQEKKLRVDLERNKRKLE---GDLKLAQESI 1067
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREAN 5079
L+ + EY + + ED L + +K + ++A E+L E
Sbjct: 1068 LDLENDKQQLDERLKKKDFEYS----QLQSKVEDEQTLSLQLQKKIKELQARIEELEEEI 1123
Query: 5080 EGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQ 5259
E RAK S+ R LE + + EL +K+
Sbjct: 1124 EA--------------ERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIEL--NKK 1167
Query: 5260 RKAQVQLEQITTDLSMERTLNQKT---EAEKQSLERSNRDYKAKITE-LESGAQSRARAQ 5427
R+A+ L + R L + T EA +L + + D A++ E +++ + + + +
Sbjct: 1168 REAEF--------LKLRRDLEEATLQHEATVATLRKKHADSAAELAEQIDNLQRVKQKLE 1219
Query: 5428 MAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKS 5607
E K++ + +VE K+ AN LEK Q + + NE+ + L +
Sbjct: 1220 KEKSEFKLEIDDLSSSVESVSKSKAN-----LEKICRTLEDQLSEARGKNEEMQRSLSEL 1274
Query: 5608 NLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
+ L+ + E ++ + + + R E+L R+L
Sbjct: 1275 TTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQIEELKRQL 1320
>gi|6981234|ref|NP_036736.1| myosin, heavy polypeptide 3; Myosin,
heavy polypeptide 3, skeletal muscle, embryonic; Myosin
heavy polypeptide 3 skeletal muscle embryonic [Rattus
norvegicus]
gi|127755|sp|P12847|MYH3_RAT Myosin heavy chain, fast skeletal
muscle, embryonic
gi|92509|pir||A24922 myosin heavy chain, skeletal muscle, embryonic -
rat
gi|1619328|emb|CAA27817.1| myosin heavy chain [Rattus norvegicus]
Length = 1940
Score = 1131 bits (2925), Expect = 0.0
Identities = 658/1890 (34%), Positives = 1052/1890 (54%), Gaps = 15/1890 (0%)
Frame = +1
Query: 85 CWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTY 264
C+V D E + G IK + +V VE D +R + + +DV NPPKFDKIEDM+ LT+
Sbjct: 38 CFVVDSKEEYAKGKIKSSQDGKVTVETED-NRTLVVKPEDVYAMNPPKFDKIEDMAMLTH 96
Query: 265 LNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIF 444
LNE +VL+NLKDRY S +IYTYSGLFCV +NPYK LP+Y+ ++++ ++GKKR E PPHIF
Sbjct: 97 LNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYTPEVVDGYRGKKRQEAPPHIF 156
Query: 445 AIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNI 624
+I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A + AA ++
Sbjct: 157 SISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATI-----------AATGDL 205
Query: 625 VQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANI 804
+K D + G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+I
Sbjct: 206 AKKKDSKMK-GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADI 264
Query: 805 EFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPN 978
E YLLEKSRV Q + ERS+HIFYQIL E E LL + +Y F+ I + +
Sbjct: 265 ETYLLEKSRVTFQLKAERSYHIFYQILSN-KKPELIELLLITTNPYDYPFISQGEILVAS 323
Query: 979 VDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQ 1158
+DD +E +T +++ I+GF +E S + ++ AV+ GN++F Q+++ +QA V
Sbjct: 324 IDDREELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVAD 383
Query: 1159 KVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTR 1338
K +L+GL +L KA PR+KVG E+V K Q +Q AV A++K+ YE+LF W+VTR
Sbjct: 384 KTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTR 443
Query: 1339 INKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEY 1518
IN+ LD T FIG+LDIAGFEIF+ NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY
Sbjct: 444 INQQLD-TKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 502
Query: 1519 QREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH----N 1686
++EGIEW FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H N
Sbjct: 503 KKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSN 562
Query: 1687 KHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIW 1866
K V ++++HF+++HYAG VDYS WL KN DPLNE VVGL Q S++ +A +
Sbjct: 563 NFQKPKVVKGKAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHL- 621
Query: 1867 KDAEFAGICAAEMNETAFGMRSRKG-MFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPN 2043
+A + + + +KG F+TVS L +E L KLM+ LR T PHFVRCIIPN
Sbjct: 622 ----YATFATTDADGGKKKVAKKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPN 677
Query: 2044 HEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFI 2220
K G + +LVL QLRCNGVLEGIRICR+GFPNR+ + +F+ RY +L IP+ FI
Sbjct: 678 ETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFI 737
Query: 2221 DGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFL 2400
D K++ K++ ++DID Y+ G +KVFF+ G+L LEE RD +L LI QA CRGFL
Sbjct: 738 DSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDERLAKLITRTQAVCRGFL 797
Query: 2401 SRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDEL 2580
R + N A++ +++W W +LF K+KPLL+ T+ E+ +E
Sbjct: 798 MRVEFQKMMQRRESIFCIQYNIRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEF 857
Query: 2581 RATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELE 2760
+ TK+ L K E +E E+KL ++ E+ +Q Q+Q ESEN + ++ +L +LE
Sbjct: 858 QKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLE 917
Query: 2761 YIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXX 2940
+ ++ +R +RK + + +K +
Sbjct: 918 AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 977
Query: 2941 XXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQ 3120
+ L E++ K K +LE Q+ +LE
Sbjct: 978 NLTEELAGLDETIAKLTREKKALQEAHQQTLDDLQAEEDKVNSLSKLKSKLEQQVDDLES 1037
Query: 3121 DLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDE 3300
L +E++ + +LE++KRKL +L+ +++ + + ++L+ +L K+D E ++ ++
Sbjct: 1038 SLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYSQLQSKVED 1097
Query: 3301 ESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDE 3480
E +QK+++++Q I+EL E++E ER R K E R + +LE++ + L++
Sbjct: 1098 EQTLSLQLQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEEL-SERLEEAGG 1156
Query: 3481 ATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRS 3657
T Q +L +++ E +R +E+ E + + K + EL +QI+ ++ +
Sbjct: 1157 VTSTQIELNKKREAEFLKLRRDLEEATLQHEATVATLRKKHADSAAELAEQIDNLQRVKQ 1216
Query: 3658 QLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLID 3837
+LEK++++ E D++ + + S+A+++K + E L E + E+ L
Sbjct: 1217 KLEKEKSEFKLEIDDLSSSVESVSKSKANLEKICRTLEDQLSEARGKNEETQRSLSELTT 1276
Query: 3838 QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQ 4017
Q R + E L+R EE+E + + R + K A + +
Sbjct: 1277 QKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQIEELKRQLEEENKAKNALAHALQS 1336
Query: 4018 LEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVE 4197
+ + L ++ EE + +A L++ + A + R K E Q+ EEL + + +
Sbjct: 1337 SRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQ 1396
Query: 4198 HLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAE 4368
LQ E+ E + + ++K+++Q E+ED +++E + +K+Q+ F+ +AE
Sbjct: 1397 RLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAE 1456
Query: 4369 ERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISN 4548
+ +++ + +A +E R T + L N + + LE R ++L+QE+ D
Sbjct: 1457 WKTKCEESQAELEAALKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQ 1516
Query: 4549 KDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRA 4728
+ GK++HELEK+++ +E E D+++ +EE E L+ E LR+++ +KSE DR
Sbjct: 1517 IAENGKSIHELEKSRKQMELEKADIQMALEEAEAALEHEEAKILRIQLELTQVKSEIDRK 1576
Query: 4729 ISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRL 4908
I+ KD E E+ +R + + ++ L+ E R ++ A+ +KK+E + E+E QL ANR
Sbjct: 1577 IAEKDEEIEQLKRNYQRTVETMQGALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQ 1636
Query: 4909 KEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGL 5088
E + Q+ ++A + +ED+ L +R+ ++AE E+LR E
Sbjct: 1637 AAETIKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQT 1696
Query: 5089 MQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQ 5259
+ARK Q K++LE + Q + A +K
Sbjct: 1697 ERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLTQLQSEVEDASRDARNAEEKA 1756
Query: 5260 RKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAAL 5439
+KA + +L E+ + E K++LE++ +D + ++ E E A + Q+ L
Sbjct: 1757 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1816
Query: 5440 EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKN 5619
E +++ LE +L E + T + + R+ E+R+ + T Q E++++ + ++L++K +K
Sbjct: 1817 ETRIRELEFELEGEQKRNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKV 1876
Query: 5620 RNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
++ +RQ +EA+++ + TK R Q E ++
Sbjct: 1877 KSYKRQAEEADEQANVHLTKFRKAQHELEE 1906
Score = 77.4 bits (189), Expect = 4e-12
Identities = 103/526 (19%), Positives = 212/526 (39%), Gaps = 22/526 (4%)
Frame = +1
Query: 4234 KERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAM 4413
K + L + ++E+ E + + SE ++K+ E ++ L A
Sbjct: 836 KIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAE 895
Query: 4414 SQELRDRETRVLSLLN-------EVDIMKEHLEESDRV-------RRSLQQELQDSISNK 4551
S+ L D E R L+ ++ + E E+ + + +R L+ E + +
Sbjct: 896 SENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 955
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQA----LKSES 4719
DD + ++EK K + E ++ ++ ++ L++ + + L+ +Q L++E
Sbjct: 956 DDLELTLAKVEKEKHATENKVKNLTEELAGLDETIAKLTREKKALQEAHQQTLDDLQAEE 1015
Query: 4720 DRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
D+ S ++++ L +Q+ DLE+ LE EK+ + +++K+E G+L+ E
Sbjct: 1016 DKVNSLSKLKSK-----LEQQVDDLESSLEQEKKLRVDLERNKRKLE---GDLKLAQESI 1067
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREAN 5079
L+ + EY + + ED L + +K + ++A E+L E
Sbjct: 1068 LDLENDKQQLDERLKKKDFEYS----QLQSKVEDEQTLSLQLQKKIKELQARIEELEEEI 1123
Query: 5080 EGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQ 5259
E RAK S+ R LE + + EL +K+
Sbjct: 1124 EA--------------ERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIEL--NKK 1167
Query: 5260 RKAQVQLEQITTDLSMERTLNQKT---EAEKQSLERSNRDYKAKITE-LESGAQSRARAQ 5427
R+A+ L + R L + T EA +L + + D A++ E +++ + + + +
Sbjct: 1168 REAEF--------LKLRRDLEEATLQHEATVATLRKKHADSAAELAEQIDNLQRVKQKLE 1219
Query: 5428 MAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKS 5607
E K++ + +VE K+ AN LEK Q + + NE+ + L +
Sbjct: 1220 KEKSEFKLEIDDLSSSVESVSKSKAN-----LEKICRTLEDQLSEARGKNEETQRSLSEL 1274
Query: 5608 NLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
+ L+ + E ++ + + + R E+L R+L
Sbjct: 1275 TTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQIEELKRQL 1320
>gi|191622|gb|AAA37161.1| alpha cardiac myosin heavy chain
Length = 1938
Score = 1130 bits (2924), Expect = 0.0
Identities = 655/1898 (34%), Positives = 1058/1898 (55%), Gaps = 20/1898 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
R C+VPD E ++ + +V E + + VTI D V + NPPKFDKIEDM+
Sbjct: 34 RTECFVPDDKEEYVKAKVVSREGGKVTAE-TENGKTVTIKEDQVMQQNPPKFDKIEDMAM 92
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LT+L+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PP
Sbjct: 93 LTFLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPP 152
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAG-ATRNKSLNAAA 612
HIF+I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQ A +A R+K N A
Sbjct: 153 HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQDFASIAAIGDRSKKENPNA 212
Query: 613 QQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYIS 792
+ G LE Q++QANP LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++
Sbjct: 213 NK------------GTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLA 260
Query: 793 GANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYL-----LEGVDNYRFLVN 957
A+IE YLLEKSRV+ Q + ER++HIFYQIL + +K E L +Y F+
Sbjct: 261 SADIETYLLEKSRVIFQLKAERNYHIFYQIL----SNKKPELLDMLLVTNNPYDYAFVSQ 316
Query: 958 RGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAML 1137
+++ ++DD +E +T ++ ++ F +E + + ++ A++ GN++F Q+++ +QA
Sbjct: 317 GEVSVASIDDSEELLATDSAFDVLSFTAEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEP 376
Query: 1138 QDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERL 1317
K +L+GL +L K PR+KVG E+V K Q+ +Q +++ A+AK+ YE++
Sbjct: 377 DGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKSVYEKM 436
Query: 1318 FKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMF 1497
F W+VTRIN +L+ T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF
Sbjct: 437 FNWMVTRINATLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMF 495
Query: 1498 ILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQK 1677
+LEQEEY++EGIEW+FIDFG+DLQ IDLIEKPMG++++L+EEC+FPKA+D +F KL
Sbjct: 496 VLEQEEYKKEGIEWEFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKASDMTFKAKLYD 555
Query: 1678 TH-NKHPKFIVP---DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTD 1845
H K F P + ++HF++VHYAG VDY+ WL KN DPLNE VVGL Q S+
Sbjct: 556 NHLGKSNNFQKPRNVKGKQEAHFSLVHYAGTVDYNIMGWLEKNKDPLNETVVGLYQKSSL 615
Query: 1846 PFVAGIWKDAEFAGICAAEMNETAFGMRSRK--GMFRTVSQLHKEQLTKLMTTLRNTSPH 2019
+A + F+ +A+ ++ G +K F+TVS LH+E L KLMT L+ T PH
Sbjct: 616 KLMATL-----FSTYASADTGDSGKGKGGKKKGSSFQTVSALHRENLNKLMTNLKTTHPH 670
Query: 2020 FVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPD 2199
FVRCIIPN K G +++ LV+ QLRCNGVLEGIRICR+GFPNR+ + +FR RY IL P
Sbjct: 671 FVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPA 730
Query: 2200 VIPK-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNF 2376
IP+ FID ++ K++ +LDID N Y+ G +KVFF+ G+L LEE RD +L+ +I
Sbjct: 731 AIPEGQFIDSRKGAEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRI 790
Query: 2377 QAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDE 2556
QAQ RG L R + N A++ ++NW W +L+ K KPLL+ T+ E
Sbjct: 791 QAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKSKPLLKSAETEKE 850
Query: 2557 IRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRL 2736
+ +E K+ L K E +E E+K+ ++ E+ +Q Q+Q E +N + ++ +L
Sbjct: 851 MANMKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQL 910
Query: 2737 QTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDK 2916
+LE V +M +RL +RK + + +K
Sbjct: 911 IKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKKDNDDLELTLAKVEKEK 970
Query: 2917 TNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLE 3096
+ + L E++ K+K +LE
Sbjct: 971 HATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKSKVKLE 1030
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
Q+ +LE L +E++ + +LE+ KRKL +L+ +++ + + +L +L K++ ++
Sbjct: 1031 QQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDIS 1090
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
Q ++ ++E A +QK++++ Q I+EL E++E ER AR K E R ++ +LE++
Sbjct: 1091 QQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEI-S 1149
Query: 3457 DVLDKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQI 3633
+ L++ AT +Q M++K E E +R +E+ E + K + V EL +QI
Sbjct: 1150 ERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQI 1209
Query: 3634 EQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESD 3813
+ ++ + +LEK++++ E D+ + + ++A+++K + E E + L E+
Sbjct: 1210 DNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQ 1269
Query: 3814 EHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKI 3993
Q + + E L R EE+E + + R + + K
Sbjct: 1270 RSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKN 1329
Query: 3994 ANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELR 4173
A + + + + L ++ EE +A L++ + A + R K E Q+ EEL
Sbjct: 1330 ALAHALQSSRHDCDLLREQYEEEMEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELE 1389
Query: 4174 KKNLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQK 4344
+ + + LQ E E + + ++K ++Q E+ED +++E A+ +K+Q+
Sbjct: 1390 EAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR 1449
Query: 4345 KFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQ 4524
F+ +AE + +++ + ++ +E R T + L N + EHLE R ++LQ+
Sbjct: 1450 NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQE 1509
Query: 4525 ELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQA 4704
E+ D + GKNVHELEK ++ LE E +++ +EE E +L+ E LR ++
Sbjct: 1510 EISDLTEQLGEGGKNVHELEKIRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQ 1569
Query: 4705 LKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQ 4884
+K+E +R ++ KD E E+ +R L+ + L+ L+ E R ++ A+ +KK+E + E+E
Sbjct: 1570 IKAEIERKLAEKDEEMEQAKRNHLRMVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEI 1629
Query: 4885 QLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQ 5064
QL ANR+ E + Q++ ++A A +D+ + +R+ ++AE E+
Sbjct: 1630 QLSQANRIASEAQKHLKNSQAHLKDTQLQLDDAVHANDDLKENIAIVERRNNLLQAELEE 1689
Query: 5065 LREANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSN 5235
LR E ++RK Q +K+++E+ + Q
Sbjct: 1690 LRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQTEVEEAVQE 1749
Query: 5236 CELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSR 5415
C A +K +KA + +L E+ + E K+++E++ +D + ++ E E A
Sbjct: 1750 CRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKG 1809
Query: 5416 ARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKEL 5595
+ Q+ LEA+V+ LE++L E + + + R+ E+R+ + T Q E++K+ + ++L
Sbjct: 1810 GKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLMRLQDL 1869
Query: 5596 LEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
++K LK + +RQ +EAE++ + +K R VQ E D+
Sbjct: 1870 VDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDE 1907
Score = 151 bits (381), Expect = 2e-34
Identities = 184/873 (21%), Positives = 373/873 (42%), Gaps = 17/873 (1%)
Frame = +1
Query: 3181 AELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTID 3360
AE E ++ E+ G+V++ + R +EL+ ++ V+L+Q++ +
Sbjct: 845 AETEKEMANMKEEFGRVKDALEKSEARRKELEEKM---------VSLLQEK--------N 887
Query: 3361 ELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT-MLQDLMSRKDEEVNATK 3537
+L+ ++ E++ N AE E QL K K + KV E T L+D +EE+NA
Sbjct: 888 DLQLQVQAEQDNLNDAE----ERCDQLIKNKIQLEAKVKEMTERLED-----EEEMNA-- 936
Query: 3538 RAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEI 3717
++ +K K + EL + + +++EK+++ + + ++ +E+
Sbjct: 937 ------------ELTAKKRKLEDECSELKKDNDDLELTLAKVEKEKHATENKVKNLTEEM 984
Query: 3718 ALLQASRADIDKKRK-IHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEE 3894
A L A + K++K + EAH + AE D+ TL + ++D L E+E
Sbjct: 985 AGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK-VNTLTKSKVKLEQQVDDLEGSLEQE 1043
Query: 3895 EHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLR 4074
+ +++R R+LE + + + E +
Sbjct: 1044 KKVRMDLERA----------------------------KRKLEGDLKLTQESIMDLENDK 1075
Query: 4075 AHLEKEIHAARQGAGEARRKAEE--SVNQQLEELRKKNLRDVEHLQKQLEESEVAKERIL 4248
LE+++ + K E+ ++ QL++ K+N +E L+++LE A+ ++
Sbjct: 1076 LQLEEKLKKKEFDISQQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVE 1135
Query: 4249 QSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELR 4428
+ + + +ELE+ S LE + + KK E++ + R +++A L +A + LR
Sbjct: 1136 KLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALR 1195
Query: 4429 DRETRVLSLLNE-VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLE 4605
+ ++ L E +D ++ ++ ++ + + EL D SN + K LEK R+LE
Sbjct: 1196 KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLE 1255
Query: 4606 AELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLL--- 4776
+ N+ RV++EE + +L R +L+ N E R + K+ + RG L
Sbjct: 1256 DQANEYRVKLEEAQRSLNDFTTQRAKLQTEN----GELARQLEEKEALISQLTRGKLSYT 1311
Query: 4777 KQIRDLENELENEKRGKSGAV----SHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXX 4944
+Q+ DL+ +LE E + K+ S R + + E+++E L+
Sbjct: 1312 QQMEDLKRQLEEEGKAKNALAHALQSSRHDCDLLREQYEEEMEAKAELQRVLSKANSEVA 1371
Query: 4945 XXXXEYQIEC----EEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXX 5112
+Y+ + EE +AK+ +A L++A+ AV A+ L + R Q
Sbjct: 1372 QWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKH-----RLQNE 1426
Query: 5113 XXXXXXXXXRAKGGGISSEEKRRLEAKI-AQXXXXXXXXQSNCELAIDKQRKAQVQLEQI 5289
R+ + ++K+R KI A+ QS E +Q + +
Sbjct: 1427 IEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE-------SSQKEARSL 1479
Query: 5290 TTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQ 5469
+T+L + +++ ++ +R N++ + +I++L + + +++ + Q
Sbjct: 1480 STELFKLKNAYEESLEHLETFKRENKNLQEEISDL-----TEQLGEGGKNVHELEKIRKQ 1534
Query: 5470 LNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEA 5649
L VE E L+ L + E E+ +A+ LE + +K + R+L E
Sbjct: 1535 LEVEKLE----------LQSALEEAEASLEHEEGKILRAQ--LEFNQIK-AEIERKLAEK 1581
Query: 5650 EDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
++EM + + H + LDA + E +
Sbjct: 1582 DEEMEQAKRNHLRMVDSLQTSLDAETRSRNEAL 1614
Score = 131 bits (329), Expect = 2e-28
Identities = 144/755 (19%), Positives = 314/755 (41%), Gaps = 44/755 (5%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + + D +E+ + +R +LE++ QE+ D+ ++ Q + D ++
Sbjct: 848 EKEMANMKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERC 907
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ L + +E L + + DE L + ++ E A ++
Sbjct: 908 DQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKKDNDDLELTLAKVE 967
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ K A N+ + L +E A LDE + A L KE
Sbjct: 968 KE---------------------KHATENKVKNLTEEM-AGLDE------IIAKLTKEKK 999
Query: 4099 AARQGAGEARR--KAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQ 4272
A ++ +A +AEE L + + K + V+ L+ LE+ + + + ++K+K++
Sbjct: 1000 ALQEAHQQALDDLQAEEDKVNTLTKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEG 1059
Query: 4273 EL---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETR 4443
+L ++S M+LEN + + K+ K+F+ ++ ++AL + + ++L++ + R
Sbjct: 1060 DLKLTQESIMDLENDKLQLEEKLKK-KEFDISQQNSKIEDEQALALQ--LQKKLKENQAR 1116
Query: 4444 VLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDM 4623
+ L E++ + + +++R L +EL++ ++ G + + EAE M
Sbjct: 1117 IEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKM 1176
Query: 4624 RVQME----------------------ELEDNLQIAEDARLRLEVTNQALKSESDRAISN 4737
R +E EL + + + + +LE K E D SN
Sbjct: 1177 RRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 1236
Query: 4738 KD--VEAEEKRRGLLKQIRDLENE----LENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
+ ++A+ + + + D NE LE +R + + R K++ + GEL +QLE
Sbjct: 1237 MEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEK 1296
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLR----EADRKFRAVEAEREQL 5067
L + + + + EE +AK +A L+ + D E E E
Sbjct: 1297 EALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSSRHDCDLLREQYEEEMEAK 1356
Query: 5068 REANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELA 5247
E L +A + + E K++L ++ + C
Sbjct: 1357 AELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSL 1416
Query: 5248 IDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQ 5427
+ + Q ++E + D+ + ++++ ++ ++K K E +S +S ++ +
Sbjct: 1417 EKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELES-SQKE 1475
Query: 5428 MAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKS 5607
+L ++ L++ + R + L++ ++D T+Q + + + +++ ++
Sbjct: 1476 ARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKIRKQL 1535
Query: 5608 NLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
++ L+ L+EAE + E K Q E + +
Sbjct: 1536 EVEKLELQSALEEAEASLEHEEGKILRAQLEFNQI 1570
Score = 99.4 bits (246), Expect = 1e-18
Identities = 130/575 (22%), Positives = 257/575 (44%), Gaps = 42/575 (7%)
Frame = +1
Query: 3046 DHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMG 3225
D +R + +AK +L +L + E+ + S LE+ K +L E+ED +
Sbjct: 1380 DAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNA 1439
Query: 3226 KVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELR-------EDMET 3384
L+ + D+ L +Y+E + + QK+ R + T + +L+ E +ET
Sbjct: 1440 AAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLET 1499
Query: 3385 -ERNARNKAE----MTRR-----EVVAQLEKVKGDV-LDKVDEATMLQDL---------- 3501
+R +N E +T + + V +LEK++ + ++K++ + L++
Sbjct: 1500 FKRENKNLQEEISDLTEQLGEGGKNVHELEKIRKQLEVEKLELQSALEEAEASLEHEEGK 1559
Query: 3502 MSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQ 3681
+ R E N K IE+ + ++E+ K R V+ L ++ + R++ + + +
Sbjct: 1560 ILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRMVDSLQTSLDAETRSRNEALRVKKK 1619
Query: 3682 ADQERADMAQEIALLQASR--ADIDKKRKIHEAHLMEIQANLAE----SDEHKRTLIDQL 3843
+ + +M EI L QA+R ++ K K +AHL + Q L + +D+ K +
Sbjct: 1620 MEGDLNEM--EIQLSQANRIASEAQKHLKNSQAHLKDTQLQLDDAVHANDDLKENIAIVE 1677
Query: 3844 ERS---RDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRAR 4014
R+ + EL+ L V E+ E + R+LA + IN+ +
Sbjct: 1678 RRNNLLQAELEELRAVVEQTERS-----RKLAEQELIETSERVQLLHSQNTSL--INQKK 1730
Query: 4015 QLEDEKNALLDEKEEA-EGLRAHLEKEIHAARQGAGEARR-KAEESVNQQLEELRKKNLR 4188
++E + L E EEA + R EK A A A K E+ + LE ++K +
Sbjct: 1731 KMESDLTQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQ 1790
Query: 4189 DVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAE 4368
++ LQ +L+E+E + L+ KK Q+LE ELEN + E QK+ AE
Sbjct: 1791 TIKDLQHRLDEAE---QIALKGGKKQLQKLEARVRELEN------ELEAEQKR----NAE 1837
Query: 4369 ERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISN 4548
++K+ ++ + + + ++ L + VD ++ ++ +R ++ + + +N
Sbjct: 1838 SVKGMRKSERRIKELTYQTEEDKKNLMRLQDLVDKLQLKVK---AYKRQAEEAEEQANTN 1894
Query: 4549 KDDFGKNVHELEKAKRS---LEAELNDMRVQMEEL 4644
F K HEL++A+ E+++N +R + ++
Sbjct: 1895 LSKFRKVQHELDEAEERADIAESQVNKLRAKSRDI 1929
>gi|24584706|ref|NP_724006.1| CG17927-PI [Drosophila melanogaster]
gi|22946666|gb|AAN10965.1| CG17927-PI [Drosophila melanogaster]
Length = 1962
Score = 1130 bits (2923), Expect = 0.0
Identities = 682/1916 (35%), Positives = 1082/1916 (55%), Gaps = 31/1916 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K CW+PD+ EG+L+G IK D V V L + + +D +Q+ NPPK++K EDMS
Sbjct: 35 KKSCWIPDEKEGYLLGEIKATKGDIVSVGLQGGETR-DLKKDLLQQVNPPKYEKAEDMSN 93
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LTYLN+ASVLHNL+ RYY+ LIYTYSGLFCV INPYK+ P+Y+ + ++GK+R+E+PP
Sbjct: 94 LTYLNDASVLHNLRQRYYNKLIYTYSGLFCVAINPYKRYPVYTNRCAKMYRGKRRNEVPP 153
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIFAI+D AY ML +QS+L TGESGAGKTENTKKVI Y A V +K + AA+
Sbjct: 154 HIFAISDGAYVDMLTNHVNQSMLITGESGAGKTENTKKVIAYFATVGA---SKKTDEAAK 210
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
G LE Q++Q NP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++G
Sbjct: 211 SK-----------GSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFGPTGKLAG 259
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLL-EGVDNYRFLVNRGITL 972
A+IE YLLEK+RV+ Q ERS+HIFYQI+ G K LL + + +Y + +T+
Sbjct: 260 ADIETYLLEKARVISQQSLERSYHIFYQIMSGSVPGVKDICLLTDNIYDYHIVSQGKVTV 319
Query: 973 PNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRV 1152
++DD +EF T + I+GF E + R+ +AV+ +G ++F Q + +QA +
Sbjct: 320 ASIDDAEEFSLTDQAFDILGFTKQEKEDVYRITAAVMHMGGMKFKQRGREEQAEQDGEEE 379
Query: 1153 IQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLV 1332
+V L G EL K L+PRIKVG EFV + +N +Q ++ A+ K ++RLFKWLV
Sbjct: 380 GGRVSKLFGCDTAELYKNLLKPRIKVGNEFVTQGRNVQQVTNSIGALCKGVFDRLFKWLV 439
Query: 1333 TRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQE 1512
+ N++LD T ++ FIG+LDIAGFEIF+ N FEQ+CIN+TNEKLQQ FN+ MF+LEQE
Sbjct: 440 KKCNETLD-TQQKRQHFIGVLDIAGFEIFEYNGFEQLCINFTNEKLQQFFNHHMFVLEQE 498
Query: 1513 EYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NK 1689
EYQREGIEW FIDFG+DLQ IDLIEKPMG+L++L+EE +FPKA D++F EKL TH K
Sbjct: 499 EYQREGIEWTFIDFGMDLQLCIDLIEKPMGILSILEEESMFPKATDQTFSEKLTNTHLGK 558
Query: 1690 HPKFIVPDM----RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVA 1857
F P + +HFA+ HYAG V Y+ WL KN DPLN+ VV + S + +
Sbjct: 559 SAPFQKPKPPKPGQQAAHFAIAHYAGCVSYNITGWLEKNKDPLNDTVVDQFKKSQNKLLI 618
Query: 1858 GIWKDAEFAGICAAEMNETAFGMRSRK-GMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCI 2034
I+ A+ AG E A G R +K G F TVS +KEQL LMTTLR+T PHFVRCI
Sbjct: 619 EIF--ADHAGQSGG--GEQAKGGRGKKGGGFATVSSAYKEQLNSLMTTLRSTQPHFVRCI 674
Query: 2035 IPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKN 2214
IPN K+ G ++++LV+ QL CNGVLEGIRICR+GFPNR+ + +F+ RY+IL P I K
Sbjct: 675 IPNEMKQPGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKMRYQILNPKGI-KG 733
Query: 2215 FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRG 2394
D K+ + +I + +++ + YR+G +KVFFR GVL +EE RD +L ++ QA RG
Sbjct: 734 IEDPKKCTKVLIESTELNDDQYRLGNTKVFFRAGVLGQMEEFRDERLGKIMSWMQAWARG 793
Query: 2395 FLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDD 2574
+LSR+ + N YL+LR W W++L+ KVKPLL V+R +DEI A+ +
Sbjct: 794 YLSRKGFKKLQEQRVALKVVQRNLRKYLQLRTWPWYKLWQKVKPLLNVSRIEDEI-ARLE 852
Query: 2575 ELRATKERLLKMEHDFRENEKKLD-QVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQ 2751
E E L E R+ + L+ +++ E+ + + L E + + +L +
Sbjct: 853 EKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQDYQERNAKLTAQKN 912
Query: 2752 ELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQ 2931
+LE + D+++RL+ ++K + + DK D
Sbjct: 913 DLENQLRDIQERLTQEEDARNQLFQQKKKADQEISGLKKDIEDLELNVQKAEQDKATKDH 972
Query: 2932 XXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHE 3111
+ + +L E++ H K K +LE L E
Sbjct: 973 QIRNLNDEIAHQDELINKLNKEKKMQGETNQKTGEELQAAEDKINHLNKVKAKLEQTLDE 1032
Query: 3112 LEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTR 3291
LE L RE++ + ++E+ KRK+ +L+ +++ +A+ +EL + ++D+EL +
Sbjct: 1033 LEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVADLERNKKELEQTIQRKDKELSSITAK 1092
Query: 3292 YDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDK 3471
++E V Q+Q++++Q I+EL E++E ER AR KAE R ++ +LE++ G+ L++
Sbjct: 1093 LEDEQVVVLKHQRQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEEL-GERLEE 1151
Query: 3472 VDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKK 3648
AT Q +L +++ E++ +R +E+ E + + K + V E+ +Q++Q K
Sbjct: 1152 AGGATSAQIELNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNK 1211
Query: 3649 QRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRT 3828
+++ EK++N+ + D+ + + +A +K K + L E+Q+ L DE RT
Sbjct: 1212 LKAKAEKEKNEYYGQLNDLRAGVDHITNEKAAQEKIAKQLQHTLNEVQSKL---DETNRT 1268
Query: 3829 LIDQLERSRDEL----DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIA 3996
L D + S+ +L L R EE E + + + + +R +
Sbjct: 1269 LND-FDASKKKLSIENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERAT 1327
Query: 3997 NINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHAARQGAGEARRKAEE---SVNQQLE 4164
+ + R LE + + L ++ +EEAEG +A L++++ A A R K E + +++LE
Sbjct: 1328 LLGKFRNLEHDLDNLREQVEEEAEG-KADLQRQLSKANAEAQVWRSKYESDGVARSEELE 1386
Query: 4165 ELRKKNLRDVEHLQKQLEESEVAKERILQ-------SKKKIQQELEDSSMELENVRASHR 4323
E ++K LQ +L E+E E + Q +K+++ E+ED +E++ A
Sbjct: 1387 EAKRK-------LQARLAEAEETIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIAN 1439
Query: 4324 DSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDR 4503
+EK+QK F+ + E ++ V + DA +E R+ T + L + +E LE R
Sbjct: 1440 AAEKKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRR 1499
Query: 4504 VRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLR 4683
++L E++D + + G+N+HE+EKA++ LEAE ++++ +EE E L+ E+ LR
Sbjct: 1500 ENKNLADEVKDLLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLR 1559
Query: 4684 LEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIEN 4863
++ ++ E DR I K+ E E R+ + + ++ LE E +GK+ A+ +KK+E
Sbjct: 1560 AQLELSQVRQEIDRRIQEKEEEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEA 1619
Query: 4864 QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRA 5043
I ELE L+ AN+ E + Q EE ++A++D L ++R+ A
Sbjct: 1620 DINELEIALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANA 1679
Query: 5044 VEAEREQ----LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXX 5211
++ E E+ L +A+ G QA ++ A+ IS+ KR+LE+++
Sbjct: 1680 LQNELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISA-AKRKLESELQTLHS 1738
Query: 5212 XXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITE 5391
+ + + +K +KA V ++ +L E+ Q E +++LE+ ++ + ++ E
Sbjct: 1739 DLDELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDE 1798
Query: 5392 LESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKR 5571
E+ A + + LE +V+ LE++L+ E + A + R+ E+R+ + + Q E++++
Sbjct: 1799 AEANALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRK 1858
Query: 5572 ANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQR---EADDLLDANEQ 5730
+E+ ++L++K K + +RQ++EAE+ + K R Q+ EA++ D EQ
Sbjct: 1859 NHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQ 1914
Score = 155 bits (391), Expect = 1e-35
Identities = 179/950 (18%), Positives = 386/950 (39%), Gaps = 62/950 (6%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDE 3267
RLE + + E+ E + + ELE KLLAE D L+ + G +++
Sbjct: 850 RLEEKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQD---------- 899
Query: 3268 ELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEK 3447
Y E +A +T Q D++ + +++E + E +ARN+ +++ ++
Sbjct: 900 --------YQERNAKLTA---QKNDLENQLRDIQERLTQEEDARNQLFQQKKKADQEISG 948
Query: 3448 VKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+K D+ D + + KD ++ I Q + K+ ++K ++ +
Sbjct: 949 LKKDIEDLELNVQKAEQDKATKDHQIRNLNDEIAH-QDELINKLNKEKKMQGETNQKTGE 1007
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAE 3807
+++ + + + L K + + +Q ++ + + R D++K ++ E L Q +A+
Sbjct: 1008 ELQAAEDKINHLNKVKAKLEQTLDELEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVAD 1067
Query: 3808 SDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL 3987
+ +K+ L ++R EL + E+E+ QR++
Sbjct: 1068 LERNKKELEQTIQRKDKELSSITAKLEDEQVVVLKHQRQIKELQA--------------- 1112
Query: 3988 KIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEE 4167
R +LE+E A + +AE RA L +E+ + GE +A + + Q+E
Sbjct: 1113 ------RIEELEEEVEAERQARAKAEKQRADLAREL----EELGERLEEAGGATSAQIE- 1161
Query: 4168 LRKKNLRDVEHLQKQLEESEVAKERILQS-KKKIQQELEDSSMELENVRASHRDSEKRQK 4344
L KK ++ L++ LEE+ + E L + +KK + + + +++ + +EK +
Sbjct: 1162 LNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNKLKAKAEKEKN 1221
Query: 4345 KFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQ 4524
++ Q+ + R V ++ A + + + + + +++D L + D ++ L
Sbjct: 1222 EYYGQLNDLRAGVDHITNEKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSI 1281
Query: 4525 ELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE--------------LE---DN 4653
E D + ++ V +L K K SL +L D + +E LE DN
Sbjct: 1282 ENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERATLLGKFRNLEHDLDN 1341
Query: 4654 L--QIAEDARLRLEVTNQALKSESDRAISNKDVEA---------EEKRRGLLKQIRDLEN 4800
L Q+ E+A + ++ Q K+ ++ + E+ EE +R L ++ + E
Sbjct: 1342 LREQVEEEAEGKADLQRQLSKANAEAQVWRSKYESDGVARSEELEEAKRKLQARLAEAEE 1401
Query: 4801 ELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEE 4980
+E+ + G ++++ ++ +L+ +++ AN + E++++ ++
Sbjct: 1402 TIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIANAAEKKQKAFDKIIGEWKLKVDD 1461
Query: 4981 ARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGG-G 5157
+ R + ++ E+ +E E + + K +GG
Sbjct: 1462 LAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGRN 1521
Query: 5158 ISSEEK--RRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKT 5331
I EK +RLEA+ + ++ E +K +AQ++L Q+ ++ +R + +K
Sbjct: 1522 IHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEI--DRRIQEKE 1579
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRARA--QMAALEAKVQYLEDQLNVEGQEKTAAN 5505
E + + + R + LE+ A+ +A A LEA + LE L+ + A
Sbjct: 1580 EEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQ 1639
Query: 5506 RAARRLEKRLNDTTQQFEDEKR----------------------------ANEQAKELLE 5601
+ +R +++L D E+E+R EQA
Sbjct: 1640 KNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRR 1699
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
++ + + QL+E + + R ++ E L ++L E N
Sbjct: 1700 QAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDELLNEAKN 1749
Score = 82.4 bits (202), Expect = 1e-13
Identities = 82/418 (19%), Positives = 183/418 (43%), Gaps = 25/418 (5%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L +Q+ E ++++ + + LE K +L A LE+++ L ++ KV +L + +E
Sbjct: 1511 LLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQE 1570
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ ++ +EE N ++ Q +D ++ +E E + +A ++++ A + ++
Sbjct: 1571 IDRRIQEKEEEFENTR------KNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINEL 1624
Query: 3451 KGDVLDKVDEATM-LQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+ LD ++A Q + R +++ + A+E+ Q + EQ R+ L +
Sbjct: 1625 E-IALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDA-REQLGISERRANALQN 1682
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL-- 3801
++E+ + Q ++ + QA+QE AD +++ + A A I ++ E+ L + ++L
Sbjct: 1683 ELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDE 1742
Query: 3802 ----AESDEHKRT--------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
A++ E K L D+L +D ++R+ E +Q RL A
Sbjct: 1743 LLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAEAN 1802
Query: 3946 XXXXXXXXXXXTRLKIANIN------RARQLEDEKNALLDEKEEAE-GLRAHLEKEIHAA 4104
++ + + R + +KN E+ E ++ +++ H
Sbjct: 1803 ALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRKNHER 1862
Query: 4105 RQGAGEARRKAEESVNQQLEELRK---KNLRDVEHLQKQLEESEVAKERILQSKKKIQ 4269
Q + ++ ++ +Q+EE + NL Q++LEE+E + Q+ K +
Sbjct: 1863 MQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQAISKFR 1920
>gi|50368680|gb|AAH76678.1| Unknown (protein for MGC:79657) [Xenopus
tropicalis]
Length = 1939
Score = 1130 bits (2922), Expect = 0.0
Identities = 669/1900 (35%), Positives = 1067/1900 (55%), Gaps = 18/1900 (0%)
Frame = +1
Query: 64 AWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIE 243
A+ + C+V D E ++ G I +V V+ D +R VT+ V NPPKFDKIE
Sbjct: 30 AFDAKNTCFVEDDKELYVKGLITAREGGKVTVKTED-ARNVTVKESQVYPQNPPKFDKIE 88
Query: 244 DMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRH 423
DM+ +T+LNEASVL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR
Sbjct: 89 DMAMMTHLNEASVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVAGYRGKKRQ 148
Query: 424 EMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLN 603
E PPHIF+I+D AY+ MLQ+RE+QS+L TGESGAGKT NTK+VIQY A +A
Sbjct: 149 EAPPHIFSISDNAYQFMLQDRENQSVLITGESGAGKTVNTKRVIQYFATIA--------- 199
Query: 604 AAAQQNIVQKPDVRNPI-GELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMS 780
A N +K ++ N + G LE Q++QANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +
Sbjct: 200 AIGDSN--KKKEMSNSMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTT 257
Query: 781 GYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLV 954
G ++ A+IE YLLEKSRV Q ERS+HIFYQIL E E LL + +Y F+
Sbjct: 258 GKLASADIETYLLEKSRVTFQLSAERSYHIFYQILTN-KKPEIVEMLLLTTNPYDYAFIS 316
Query: 955 NRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAM 1134
I + ++DD +E +T +++ I+GF +E I ++ +V+ GN++F Q+++ +QA
Sbjct: 317 QGEIAVKSIDDEEELMATDSAIDILGFTAEEKMGIYKMTGSVMHKGNMKFKQKQREEQAE 376
Query: 1135 LQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYER 1314
V K+ +L+GL +L KA PR+KVG EFV K Q +Q A+ A++K+ +E+
Sbjct: 377 PDGTEVADKIGYLMGLNSADLLKALCYPRVKVGNEFVTKGQTVQQVYNAIGALSKSVFEK 436
Query: 1315 LFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTM 1494
LF W+VTRIN+ LD T FIG+LDIAGFEIFD+NS EQ+CIN+TNEKLQQ FN+ M
Sbjct: 437 LFLWMVTRINQQLD-TKLPRQYFIGVLDIAGFEIFDLNSLEQLCINFTNEKLQQFFNHHM 495
Query: 1495 FILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQ 1674
F+LEQEEY++EGI+W+FIDFG+DL I+LIEKPMG+L++L+EEC+FPKA D SF KL
Sbjct: 496 FVLEQEEYKKEGIDWEFIDFGMDLAACIELIEKPMGILSILEEECMFPKATDTSFKNKLY 555
Query: 1675 KTH-NKHPKFIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNST 1842
H K F P ++++HF++VHYAG VDY+ WL KN DPLNE VVGL Q S+
Sbjct: 556 DQHLGKCKNFEKPKPAKGKAEAHFSLVHYAGTVDYNICGWLDKNKDPLNETVVGLYQKSS 615
Query: 1843 DPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHF 2022
++ ++ + +AG A + G + + F+TVS L +E L KLMT LR+T PHF
Sbjct: 616 LKLLSFLY--SSYAGTDGAG-DGAKSGKKKKGSSFQTVSALFRENLNKLMTNLRSTHPHF 672
Query: 2023 VRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDV 2202
VRC+IPN K G + ++L++ QLRCNGVLEGIRICR+GFP+R+ + +F+ RY+IL
Sbjct: 673 VRCLIPNESKTPGIMENHLIIHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKILNASA 732
Query: 2203 IPK-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQ 2379
IP FID K++ K++ ++DID YR G +KVFF+ G+L LEE RD KL LI Q
Sbjct: 733 IPDGQFIDSKKACEKLLGSIDIDHTQYRFGHTKVFFKAGLLGTLEEMRDDKLAQLITRTQ 792
Query: 2380 AQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEI 2559
A CRGFL R + N +++ +++W W +L+ K+KPLL+ T+ E+
Sbjct: 793 ALCRGFLMRVEFKKMIERRDAIFVIQYNVRSFMNVKHWPWMKLYFKIKPLLKSAETEKEM 852
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
+E TKE L K + +E E+K+ ++ E+ + Q Q E+E+ A+ ++ L
Sbjct: 853 ANMKEEFEKTKEALTKSDARRKELEEKMVALLQEKNDLMLQCQSENESLADAEERCEGLI 912
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
LE + ++ +RL +RK + + +K
Sbjct: 913 KNKINLEAKIKELTERLEDEEESNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKH 972
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLEN 3099
+ + L E++ KAK +LE
Sbjct: 973 ATENKVKNLTEEMAGLDETISKISKEKKALQEAHQQTLDDLQAEEDKVSSLSKAKTKLEQ 1032
Query: 3100 QLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQH 3279
Q+ +LE L +E++ + +LE+ KRKL +L+ +++ + + ++ +L K+D EL
Sbjct: 1033 QVDDLEGSLEQEKKLRLDLERAKRKLEGDLKLAQETIMDLENDKQQTEEKLKKKDFELSQ 1092
Query: 3280 QLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGD 3459
+ ++E + +QK+++++Q I+E+ E++E ER AR K E R ++ +LE++ +
Sbjct: 1093 LQGKIEDEQSVGCQLQKKIKELQARIEEVEEEIEAERAARAKVEKQRADLSRELEEI-SE 1151
Query: 3460 VLDKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIE 3636
L++ AT Q M++K E E +R +E+ E + K + V EL +QI+
Sbjct: 1152 RLEEAGGATSAQIEMNKKREAEFQKLRRDLEESTLQHEATSAALRKKHADSVAELGEQID 1211
Query: 3637 QHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDE 3816
++ + +LEK++++ E D+A + + S+A+++K ++ E L EI+ + DE
Sbjct: 1212 NLQRVKQKLEKEKSELKMEIDDLASNLENVSKSKANLEKLSRVLEDQLSEIK---SRDDE 1268
Query: 3817 HKRTLID---QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL 3987
H+R + D Q R + E L+R EE+E + + R T+
Sbjct: 1269 HQRIINDLTAQKARLQTENGELSRQLEEKESLVSQLTRGKQGFTQQTEELKRQLEEETKA 1328
Query: 3988 KIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEE 4167
K A + + + + L ++ EE + +A L++ + A + R K E Q+ EE
Sbjct: 1329 KNALAHALQSSRHDCDLLREQYEEEQEAKAELQRSLSKANTEVSQWRTKYETDAIQRTEE 1388
Query: 4168 LRKKNLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKR 4338
L + + + LQ+ E+ E + + ++K+++Q E+ED +++E ++ +K+
Sbjct: 1389 LEEAKKKLAQRLQEAEEQVEAVNSKCASLEKTKQRLQAEVEDLMVDVERANSAAAALDKK 1448
Query: 4339 QKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSL 4518
Q+ F+ + E + +++ + +A +E R T + + N + EHLE R ++L
Sbjct: 1449 QRNFDKVLVEWKQKYEESQAELEASQKESRSLSTEIFKMKNAYEEALEHLETMKRENKNL 1508
Query: 4519 QQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTN 4698
QQE+ D + K ELEKAK+ +E E D++ +EE E +L+ E LR+++
Sbjct: 1509 QQEISDLSEQIGESAKTTMELEKAKKQVEQERGDLQAALEEAEGSLEHEEAKILRIQLEL 1568
Query: 4699 QALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGEL 4878
+KSE DR I+ KD E E+ +R + I +++ L++E R ++ A+ +KK+E + EL
Sbjct: 1569 NQVKSEVDRKIAEKDEEIEQLKRNSQRVIDTMQSTLDSEIRSRNDALRLKKKMEGDLNEL 1628
Query: 4879 EQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAER 5058
E QL ANR E + QI +++ +A+ED+ L DR+ +AE
Sbjct: 1629 EIQLGHANRQAGEAQKQLRNVQAQLKDTQIHLDDSVRAQEDLKEQLAVVDRRTTLQQAEI 1688
Query: 5059 EQLREANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQ 5229
E++R A E ++RK Q K++LE
Sbjct: 1689 EEMRVALEQTERSRKMAEQELLDASERVQLLHSQNTSLINTKKKLETDAGTLQNEMEEAV 1748
Query: 5230 SNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQ 5409
A +K +KA + +L E+ + E K++LE++ +D + ++ E E A
Sbjct: 1749 QEARNAEEKAKKAITDAALMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLAM 1808
Query: 5410 SRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAK 5589
+ Q+ LE++V+ LE++L+ E + A + R+ E+R+ + T Q E++++ + +
Sbjct: 1809 KGGKKQLQKLESRVRELENELDNEQKRSVEAVKGVRKYERRVKELTYQSEEDRKNVLRLQ 1868
Query: 5590 ELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+L++K LK + +RQ +E+E++ + + R VQ E ++
Sbjct: 1869 DLVDKLQLKVKAYKRQAEESEEQANAHLARFRKVQHELEE 1908
Score = 107 bits (268), Expect = 3e-21
Identities = 141/753 (18%), Positives = 297/753 (38%), Gaps = 25/753 (3%)
Frame = +1
Query: 2533 QVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAE 2712
++ + E++ + D+L + E + K + N +KL +V+ ++ + E ++ E+
Sbjct: 1219 KLEKEKSELKMEIDDLASNLENVSKS----KANLEKLSRVLEDQ--LSEIKSRDDEHQRI 1272
Query: 2713 LDDI---RGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXX 2883
++D+ + RLQT N EL + ++ S ++ E R
Sbjct: 1273 INDLTAQKARLQTENGELS---RQLEEKESLVSQLTRGKQGFTQQTEELKRQLEEETKAK 1329
Query: 2884 XXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERA 3063
+ + D + T + E
Sbjct: 1330 NALAHALQSSRHDCDLLREQYEEEQEAKAELQRSLSKANTEVSQWRTKYETDAIQRTEEL 1389
Query: 3064 KHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELN 3243
+ +AK +L +L E E+ + + LE+ K++L AE+ED + L+
Sbjct: 1390 E---EAKKKLAQRLQEAEEQVEAVNSKCASLEKTKQRLQAEVEDLMVDVERANSAAAALD 1446
Query: 3244 NQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRR 3423
+ D+ L +Y+E A + QK+ R + T I +++ E A E +R
Sbjct: 1447 KKQRNFDKVLVEWKQKYEESQAELEASQKESRSLSTEIFKMKNAYE---EALEHLETMKR 1503
Query: 3424 EVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKF- 3600
E L++ D+ +++ E+ + + ++V + ++ EG +E ++AK
Sbjct: 1504 EN-KNLQQEISDLSEQIGESAKTTMELEKAKKQVEQERGDLQAALEEAEGSLEHEEAKIL 1562
Query: 3601 -------------SRQVEELHDQIEQHKKQRSQ-LEKQQNQADQERADMAQEIALLQASR 3738
R++ E ++IEQ K+ + ++ Q+ D E + L +
Sbjct: 1563 RIQLELNQVKSEVDRKIAEKDEEIEQLKRNSQRVIDTMQSTLDSEIRSRNDALRLKKKME 1622
Query: 3739 ADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
D+++ E L E+ + R + QL+ ++ LD R +E+ + A +
Sbjct: 1623 GDLNEL----EIQLGHANRQAGEAQKQLRNVQAQLKDTQIHLDDSVRAQEDLKEQLAVVD 1678
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
RR R+ + R+R++ +++ LLD E + L + I+
Sbjct: 1679 RR--------TTLQQAEIEEMRVALEQTERSRKMAEQE--LLDASERVQLLHSQNTSLIN 1728
Query: 4099 AARQ---GAGEARRKAEESVNQ--QLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKK 4263
++ AG + + EE+V + EE KK + D + ++L++ + + + KK
Sbjct: 1729 TKKKLETDAGTLQNEMEEAVQEARNAEEKAKKAITDAALMAEELKKEQDTSAHLERMKKN 1788
Query: 4264 IQQELEDSSMELENV-RASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRET 4440
++Q ++D L+ + + + +K+ +K ES++ E + + +R E
Sbjct: 1789 LEQTVKDLQHRLDEAEQLAMKGGKKQLQKLESRVRELENELDNEQKRSVEAVKGVRKYER 1848
Query: 4441 RVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNK-DDFGKNVHELEKAKRSLEAELN 4617
RV L + E DR Q+L D + K + + E E+ + A
Sbjct: 1849 RVKELTYQ--------SEEDRKNVLRLQDLVDKLQLKVKAYKRQAEESEEQANAHLARFR 1900
Query: 4618 DMRVQMEELEDNLQIAEDARLRLEVTNQALKSE 4716
++ ++EE E+ IAE +L ++ + S+
Sbjct: 1901 KVQHELEESEERADIAESQVNKLRAKSRDIGSK 1933
Score = 72.0 bits (175), Expect = 2e-10
Identities = 104/538 (19%), Positives = 218/538 (40%), Gaps = 36/538 (6%)
Frame = +1
Query: 4234 KERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAM 4413
K + L + ++E+ + E E + + S+ R+K+ E +M +L +
Sbjct: 838 KIKPLLKSAETEKEMANMKEEFEKTKEALTKSDARRKELEEKMVALLQEKNDLMLQCQSE 897
Query: 4414 SQELRDRETRVLSLL-NEVDI------MKEHLEESDRV-------RRSLQQELQDSISNK 4551
++ L D E R L+ N++++ + E LE+ + +R L+ E + +
Sbjct: 898 NESLADAEERCEGLIKNKINLEAKIKELTERLEDEEESNAELTAKKRKLEDECSELKKDI 957
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNL-QIAEDARLRLEVTNQALKSESDRA 4728
DD + ++EK K + E ++ ++ +M L++ + +I+++ + E Q L + +A
Sbjct: 958 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETISKISKEKKALQEAHQQTL--DDLQA 1015
Query: 4729 ISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRL 4908
+K + + L +Q+ DLE LE EK+ + ++K+E + ++ +
Sbjct: 1016 EEDKVSSLSKAKTKLEQQVDDLEGSLEQEKKLRLDLERAKRKLEGDLKLAQETIMDLEND 1075
Query: 4909 KEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGL 5088
K++ + Q + E+ + + ++E + VE E E R A
Sbjct: 1076 KQQTEEKLKKKDFELSQLQGKIEDEQSVGCQLQKKIKELQARIEEVEEEIEAERAA---- 1131
Query: 5089 MQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKA 5268
RAK ++ R LE +
Sbjct: 1132 -----------------RAKVEKQRADLSRELE-------------------------EI 1149
Query: 5269 QVQLEQITTDLSMERTLNQKTEAE----KQSLERSNRDYKAKITEL---------ESGAQ 5409
+LE+ S + +N+K EAE ++ LE S ++A L E G Q
Sbjct: 1150 SERLEEAGGATSAQIEMNKKREAEFQKLRRDLEESTLQHEATSAALRKKHADSVAELGEQ 1209
Query: 5410 ----SRARAQMAALEAKVQYLEDQL--NVEGQEKTAAN--RAARRLEKRLNDTTQQFEDE 5565
R + ++ +++++ D L N+E K+ AN + +R LE +L++ + ++
Sbjct: 1210 IDNLQRVKQKLEKEKSELKMEIDDLASNLENVSKSKANLEKLSRVLEDQLSEIKSRDDEH 1269
Query: 5566 KRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTR 5739
+R + +N L RQL+E E +S+ + ++ ++L E+ T+
Sbjct: 1270 QRIINDLTAQKARLQTENGELSRQLEEKESLVSQLTRGKQGFTQQTEELKRQLEEETK 1327
>gi|3043372|sp|P11055|MYH3_HUMAN Myosin heavy chain, fast skeletal
muscle, embryonic (Muscle embryonic myosin heavy chain)
(SMHCE)
Length = 1940
Score = 1128 bits (2917), Expect = 0.0
Identities = 658/1890 (34%), Positives = 1052/1890 (54%), Gaps = 15/1890 (0%)
Frame = +1
Query: 85 CWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTY 264
C+V D E + G IK + +V VE D +R + + +DV NPPKFD+IEDM+ LT+
Sbjct: 38 CFVVDSKEEYAKGKIKSSQDGKVTVETED-NRTLVVKPEDVYAMNPPKFDRIEDMAMLTH 96
Query: 265 LNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIF 444
LNE +VL+NLKDRY S +IYTYSGLFCV +NPYK LP+Y+ +++E ++GKKR E PPHIF
Sbjct: 97 LNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIF 156
Query: 445 AIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNI 624
+I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A + AA ++
Sbjct: 157 SISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATI-----------AATGDL 205
Query: 625 VQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANI 804
+K D + G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+I
Sbjct: 206 AKKKDSKMK-GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADI 264
Query: 805 EFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPN 978
E YLLEKSRV Q + ERS+HIFYQIL E E LL + +Y F+ I + +
Sbjct: 265 ETYLLEKSRVTFQLKAERSYHIFYQILSN-KKPELIELLLITTNPYDYPFISQGEILVAS 323
Query: 979 VDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQ 1158
+DD +E +T +++ I+GF +E S + ++ AV+ GN++F Q+++ +QA V
Sbjct: 324 IDDREELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVAD 383
Query: 1159 KVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTR 1338
K +L+GL +L KA PR+KVG E+V K Q +Q AV A++K+ YE+LF W+VTR
Sbjct: 384 KTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTR 443
Query: 1339 INKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEY 1518
IN+ LD T FIG+LDIAGFEIF+ NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY
Sbjct: 444 INQQLD-TKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 502
Query: 1519 QREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH----N 1686
++EGIEW FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H N
Sbjct: 503 KKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSN 562
Query: 1687 KHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIW 1866
K V R+++HF+++HYAG VDYS WL KN DPLNE VVGL Q S++ +A +
Sbjct: 563 NFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHL- 621
Query: 1867 KDAEFAGICAAEMNETAFGMRSRKG-MFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPN 2043
+A A+ + + +KG F+TVS L +E L KLM+ LR T PHFVRCIIPN
Sbjct: 622 ----YATFATADADSGKKKVAKKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPN 677
Query: 2044 HEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPD-VIPKNFI 2220
K G + +LVL QLRCNGVLEGIRICR+GFPNR+ + +F+ RY +L ++ FI
Sbjct: 678 ETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAILEGQFI 737
Query: 2221 DGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFL 2400
D K++ K++ ++DID Y+ G +KVFF+ G+L LEE RD +L LI QA CRGFL
Sbjct: 738 DSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGFL 797
Query: 2401 SRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDEL 2580
R + N +++ +++W W +LF K+KPLL+ T+ E+ +E
Sbjct: 798 MRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEF 857
Query: 2581 RATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELE 2760
+ TK+ L K E +E E+KL ++ E+ +Q Q+Q ESEN + ++ +L +LE
Sbjct: 858 QKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLE 917
Query: 2761 YIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXX 2940
+ ++ +R +RK + + +K +
Sbjct: 918 AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 977
Query: 2941 XXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQ 3120
+ L E++ K K +LE Q+ +LE
Sbjct: 978 NLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLES 1037
Query: 3121 DLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDE 3300
L +E++ + +LE++KRKL +L+ +++ + + ++L+ +L K+D E ++ ++
Sbjct: 1038 SLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVED 1097
Query: 3301 ESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDE 3480
E QK+++++Q I+EL E++E ER R K E R + +LE++ + L++
Sbjct: 1098 EQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEEL-SERLEEAGG 1156
Query: 3481 ATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRS 3657
T Q +L +++ E +R +E+ E + + K + V EL +QI+ ++ +
Sbjct: 1157 VTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQ 1216
Query: 3658 QLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLID 3837
+LEK++++ E D++ + + S+A+++K + E L E + E L
Sbjct: 1217 KLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTT 1276
Query: 3838 QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQ 4017
Q R + E L+R EE+E + + R + K A + +
Sbjct: 1277 QKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQS 1336
Query: 4018 LEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVE 4197
+ + L ++ EE + +A L++ + A + R K E Q+ EEL + + +
Sbjct: 1337 SRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQ 1396
Query: 4198 HLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAE 4368
LQ E+ E + + ++K+++Q E+ED +++E + +K+Q+ F+ +AE
Sbjct: 1397 RLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAE 1456
Query: 4369 ERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISN 4548
+ +++ + +A +E R T + L N + + LE R ++L+QE+ D
Sbjct: 1457 WKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQ 1516
Query: 4549 KDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRA 4728
+ GK +HELEK+++ +E E D+++ +EE E L+ E LR+++ +KSE DR
Sbjct: 1517 IAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRK 1576
Query: 4729 ISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRL 4908
I+ KD E E+ +R + + +++ L+ E R ++ A+ +KK+E + E+E QL ANR
Sbjct: 1577 IAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQ 1636
Query: 4909 KEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGL 5088
E + Q+ ++A + +ED+ L +R+ ++AE E+LR E
Sbjct: 1637 AAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQT 1696
Query: 5089 MQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQ 5259
+ARK Q K++LE + Q + A +K
Sbjct: 1697 ERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKA 1756
Query: 5260 RKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAAL 5439
+KA + +L E+ + E K++LE++ +D + ++ E E A + Q+ L
Sbjct: 1757 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1816
Query: 5440 EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKN 5619
E +++ LE +L E ++ T + + R+ E+R+ + T Q E++++ + ++L++K +K
Sbjct: 1817 ETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKV 1876
Query: 5620 RNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
++ +RQ +EA+++ + TK R Q E ++
Sbjct: 1877 KSYKRQAEEADEQANAHLTKFRKAQHELEE 1906
Score = 77.0 bits (188), Expect = 5e-12
Identities = 105/527 (19%), Positives = 215/527 (39%), Gaps = 16/527 (3%)
Frame = +1
Query: 4213 LEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQ-- 4386
L+ +E KE +++E + + EL A ++ E++ + + ++ VQ
Sbjct: 841 LKSAETEKEMAT-----MKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAE 895
Query: 4387 -KALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFG 4563
+ LLD + +L + ++ + + EV E EE + + +++L+D S +
Sbjct: 896 SENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECS---ELK 952
Query: 4564 KNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
K++ +LE +E E + +++ L + L ++ +L +AL+ +A+ D
Sbjct: 953 KDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALD--D 1010
Query: 4744 VEAEEKRRGLL--------KQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
++AEE + L +Q+ DLE+ LE EK+ + +++K+E + ++ +
Sbjct: 1011 LQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDL 1070
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREAN 5079
K++ + Q + E+ + ++E + +E E E R
Sbjct: 1071 ENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATR 1130
Query: 5080 EGLMQARKQXXXXXXXXXXXRAKGGGISSEE-----KRRLEAKIAQXXXXXXXXQSNCEL 5244
+ R + GG++S + KR E + Q +
Sbjct: 1131 AKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMV 1190
Query: 5245 AIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARA 5424
A +++ A E +++R KQ LE+ ++K +I +L S +S +++
Sbjct: 1191 ATLRKKHADSVAELGEQIDNLQRV--------KQKLEKEKSEFKLEIDDLSSSMESVSKS 1242
Query: 5425 QMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEK 5604
+ A LE + LEDQL+ A +++ L++ T Q + R +A EL
Sbjct: 1243 K-ANLEKICRTLEDQLS-------EARGKNEEIQRSLSELTTQ---KSRLQTEAGEL--- 1288
Query: 5605 SNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
RQL+E E +S+ + R E+L R+L
Sbjct: 1289 --------SRQLEEKESIVSQ-------LSRSKQAFTQQTEELKRQL 1320
>gi|9800488|gb|AAF99315.1| fast myosin heavy chain isoform 3 [Gallus
gallus]
Length = 1941
Score = 1127 bits (2916), Expect = 0.0
Identities = 656/1891 (34%), Positives = 1060/1891 (55%), Gaps = 17/1891 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V E F+ G+I+ +V V+ + +T+ D V NPPK+DKIEDM+ +T+L
Sbjct: 40 FVAHPKESFVKGTIQSRETGKVTVK-TEGGETLTVKEDQVFSMNPPKYDKIEDMAMMTHL 98
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 99 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVLAYRGKKRQEAPPHIFS 158
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A + K + +
Sbjct: 159 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAASGEKKKEEQSGKMQ-- 216
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
G LE Q++ ANP+LEAFGN++TV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 217 ---------GTLEDQIISANPLLEAFGNAETVRNDNSSRFGKFIRIHFGATGKLASADIE 267
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPNV 981
YLLEKSRV Q + ERS+HIFYQI+ E + LL + +Y F+ IT+P++
Sbjct: 268 TYLLEKSRVTFQLKAERSYHIFYQIMSN-KKPELIDMLLITTNPYDYHFVSQGEITVPSI 326
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
DD +E +T +++ I+GF DE ++I ++ AV+ GNL+F Q+++ +QA V K
Sbjct: 327 DDQEELMATDSAIDILGFTADEKTAISKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADK 386
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L+GL +L KA PR+KVG E+V K Q +Q AV A+AKA YE++F W+V RI
Sbjct: 387 AAYLMGLNSADLLKALCYPRVKVGNEYVTKGQTVQQVHNAVGALAKAVYEKMFLWMVVRI 446
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 447 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H K
Sbjct: 506 KEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSSN 565
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P ++++HF++VHYAG VDY+ WL KN DPLNE V+GL Q S+ +A ++
Sbjct: 566 FQKPKPAKGKAEAHFSLVHYAGTVDYNITGWLEKNKDPLNETVIGLYQKSSVKTLALLF- 624
Query: 1870 DAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHE 2049
A + G A G + + F+TVS L +E L KLMT LR+T PHFVRCIIPN
Sbjct: 625 -ATYGGADAEAGGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 683
Query: 2050 KKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDG 2226
K G + LVL QLRCNGVLEGIRICR+GFP+RV + +F+ RY++L IP+ FID
Sbjct: 684 KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRVLYADFKQRYKVLNASAIPEGQFIDS 743
Query: 2227 KESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSR 2406
K++ K+++++D+D Y+ G +KVFF+ G+L LEE RD KL LI QA+ RGFL R
Sbjct: 744 KKASEKLLSSIDVDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQARSRGFLMR 803
Query: 2407 RLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRA 2586
Y N +++ +++W W +LF K+KPLL+ ++ E+ +E
Sbjct: 804 VEYQRMVERRESIFCIQYNVRSFMNVKHWPWMKLFFKIKPLLKSAESEKEMANMKEEFEK 863
Query: 2587 TKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYI 2766
TKE L K E +E E+K+ +++ E+ +Q Q+Q E+++ A+ ++ +L +LE
Sbjct: 864 TKEELAKSEAKRKELEEKMVKLVQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAK 923
Query: 2767 VNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXX 2946
+ ++ +R +RK + + +K +
Sbjct: 924 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDMDDLELTLAKVEKEKHATENKVKNL 983
Query: 2947 XXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDL 3126
+ L E++ KAK +LE Q+ +LE L
Sbjct: 984 TEEMAALDETIVKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSL 1043
Query: 3127 NRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEES 3306
+E++ + +LE+ KRKL +L+ + D + + ++L+ +L K+D E+ ++ ++E
Sbjct: 1044 EQEKKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQ 1103
Query: 3307 ANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT 3486
A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L++ AT
Sbjct: 1104 ALGMQLQKKIKELQARIEELEEEIEAERTSRAKAEKHRADLSRELEEI-SERLEEAGGAT 1162
Query: 3487 MLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQL 3663
Q D+ +++ E +R +E+ E + K + EL +QI+ ++ + +L
Sbjct: 1163 AAQIDMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKL 1222
Query: 3664 EKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLID-- 3837
EK++++ E D+A + + ++A+++K + E L EI+ + +EH+R + D
Sbjct: 1223 EKEKSELKMEIDDLASNMESVSKAKANLEKMCRTLEDQLSEIK---TKEEEHQRMINDLN 1279
Query: 3838 -QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRAR 4014
Q R + E +R EE++ + + R + K A + +
Sbjct: 1280 TQRARLQTEAGEYSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKNALAHALQ 1339
Query: 4015 QLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDV 4194
+ + L ++ EE + + L++ + A + R K E Q+ EEL + +
Sbjct: 1340 SARHDCDLLREQYEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA 1399
Query: 4195 EHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMA 4365
+ LQ E E + + ++K+++Q E+ED +++E A+ +K+QK F+ +A
Sbjct: 1400 QRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERANAACAALDKKQKNFDKILA 1459
Query: 4366 EERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSIS 4545
E + ++ + +A +E R T + + N + +HL+ R ++LQQE+ D
Sbjct: 1460 EWKQKYEETQAELEASQKESRSLSTELFKMKNAYEESLDHLQTLKRENKNLQQEISDLTE 1519
Query: 4546 NKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDR 4725
+ GK +HELEK K+ +E E ++++ +EE E +L+ E LRL++ +KSE DR
Sbjct: 1520 QIAEGGKAIHELEKVKKQIEQEKSEIQAALEEAEASLEHEEGKILRLQLELNQVKSEIDR 1579
Query: 4726 AISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANR 4905
I+ KD E ++ +R L+ + L++ L+ E R ++ A+ +KK+E + E+E QL ANR
Sbjct: 1580 KIAEKDEEIDQLKRNHLRIVESLQSSLDAEIRSRNEALRLKKKMEGDLNEMEIQLSHANR 1639
Query: 4906 LKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEG 5085
+ E + QI ++A + +E + + +R+ ++AE E+LR A E
Sbjct: 1640 VAAEAQKNLRNTQAVLKDTQIHLDDALRTQEVLKEQVAMVERRANLLQAEIEELRAALEQ 1699
Query: 5086 LMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDK 5256
++RK Q K++LE IAQ +K
Sbjct: 1700 TERSRKVAEQELMDASERVQLLHTQNTSLINTKKKLETDIAQIQSEMEDTIQEARNTEEK 1759
Query: 5257 QRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAA 5436
+KA + +L E+ + E K++L+++ +D + ++ E E A + Q+
Sbjct: 1760 AKKAITDAAMMAEELKKEQDTSAHLERMKKNLDQTVKDLQHRLDEAEQLALKGGKKQIQK 1819
Query: 5437 LEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLK 5616
LEA+V+ LE +++ E + A + R+ E+R+ + T Q E++ + + ++L++K +K
Sbjct: 1820 LEARVRELEGEVDAEQKRSAEAVKGVRKYERRVKELTYQSEEDLKNILRLQDLVDKLQMK 1879
Query: 5617 NRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
++ +RQ +EAE+ + +K R +Q E ++
Sbjct: 1880 VKSYKRQAEEAEELSNVNLSKFRKIQHELEE 1910
Score = 165 bits (418), Expect = 1e-38
Identities = 190/929 (20%), Positives = 390/929 (41%), Gaps = 43/929 (4%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + + +++L + + ELE+ KL+ E D + + A+ + EE +
Sbjct: 852 KEMANMKEEFEKTKEELAKSEAKRKELEEKMVKLVQEKNDLQLQVQAEADSLADAEERCD 911
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE N L K+ R ++ EL++DM+ E
Sbjct: 912 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKDMDD-------LE 963
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E L + + + +E A + A +Q ++ +
Sbjct: 964 LTLAKVEKEKHATENKVKNLTEEMAALDETIVKLTKEKKALQEAHQQTLDDLQAEEDKVN 1023
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK 3753
+ + K K +QV++L +EQ KK R LE+ + + + + I L+ + +D+
Sbjct: 1024 TLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDE 1083
Query: 3754 KRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLAT 3933
K K + + +IQ+ + E ++ L QL++ EL R+ E EE A R
Sbjct: 1084 KLKKKDFEISQIQSKI----EDEQALGMQLQKKIKELQ--ARIEELEEEIEAERTSRAKA 1137
Query: 3934 AXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQG 4113
RL+ A A Q++ +++K EAE
Sbjct: 1138 EKHRADLSRELEEISERLEEAGGATAAQID------MNKKREAE---------------- 1175
Query: 4114 AGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELED 4284
+ RR EE+ Q LRKK+ L +Q++ + K+++ + K +++ E++D
Sbjct: 1176 FQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDD 1235
Query: 4285 SSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNE 4464
+ +E+V + + EK + E Q++E + + + + D T+ L E
Sbjct: 1236 LASNMESVSKAKANLEKMCRTLEDQLSEIKT-------KEEEHQRMINDLNTQRARLQTE 1288
Query: 4465 VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEEL 4644
+EE D + L + Q ++ +++ E KAK +L L R + L
Sbjct: 1289 AGEYSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKNALAHALQSARHDCDLL 1348
Query: 4645 EDNLQIAEDARLRL---------EVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLE 4797
+ + ++A+ L EV K E+D AI + E EE ++ L ++++D E
Sbjct: 1349 REQYEEEQEAKGELQRALSKANSEVAQWRTKYETD-AIQRTE-ELEEAKKKLAQRLQDAE 1406
Query: 4798 NELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECE 4977
+E + +++++N++ +L +E AN +
Sbjct: 1407 EHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERAN-------AACAALDKKQKNFDKILA 1459
Query: 4978 EARQAKEDIAALLREADRKFRAVEAEREQLREANE-------GLMQARKQXXXXXXXXXX 5136
E +Q E+ A L + ++ R++ E +++ A E L + K
Sbjct: 1460 EWKQKYEETQAELEASQKESRSLSTELFKMKNAYEESLDHLQTLKRENKNLQQEISDLTE 1519
Query: 5137 XRAKGGGISSE---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSM 5307
A+GG E K+++E + ++ +++ E K + Q++L Q+ ++
Sbjct: 1520 QIAEGGKAIHELEKVKKQIEQEKSEIQAALEEAEASLEHEEGKILRLQLELNQVKSE--- 1576
Query: 5308 ERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQ 5487
+++K + + +++ R++ + L+S + R++ AL K + +E LN
Sbjct: 1577 ---IDRKIAEKDEEIDQLKRNHLRIVESLQSSLDAEIRSRNEALRLK-KKMEGDLNEMEI 1632
Query: 5488 EKTAANRAARRLEKR-------LNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDE 5646
+ + ANR A +K L DT +D R E KE + + L+ +++E
Sbjct: 1633 QLSHANRVAAEAQKNLRNTQAVLKDTQIHLDDALRTQEVLKEQVAMVERRANLLQAEIEE 1692
Query: 5647 AEDEMSRERTKHRNVQREADDLLDANEQL 5733
+ + + ++E L+DA+E++
Sbjct: 1693 LRAALEQTERSRKVAEQE---LMDASERV 1718
Score = 136 bits (343), Expect = 5e-30
Identities = 183/904 (20%), Positives = 363/904 (39%), Gaps = 135/904 (14%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ + ++ +E+D ++ ++KL + E + IQ +++ E +L LQ
Sbjct: 1058 RKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQ 1117
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + +R S R ++E + + +
Sbjct: 1118 ARIEELEEEIE--AERTSRAKAEKHRADLSR--ELEEISERLEEAGGATAAQIDMNKKRE 1173
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K L+
Sbjct: 1174 AEFQKMRRDLEEATLQHEATAAALRKKHADSTAELG---EQIDNLQRVKQKLEKEKSELK 1230
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K+ LE+ R L +L + K E + +LN Q + E
Sbjct: 1231 MEIDDLASNMESVSKAKANLEKMCRTLEDQLSEIKTKEEEHQRMINDLNTQRARLQTEAG 1290
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ +E+ A ++ + + + I+EL+ +E E A+N + + ++
Sbjct: 1291 EYSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKNALAHALQSARHDCDLLRE 1350
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
++ + LQ +S+ + EV TK + IQ T E +EE K K ++++++ +
Sbjct: 1351 QYEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQDAEEH 1408
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME-------I 3789
+E + + LEK + + E D+ ++ A+ A +DKK+K + L E
Sbjct: 1409 VEAVNAKCASLEKTKQRLQNEVEDLMIDVERANAACAALDKKQKNFDKILAEWKQKYEET 1468
Query: 3790 QANLAESDEHKRTLIDQLERSR----DELDHLNRVREEEEHAFANMQRRLATAXXXXXXX 3957
QA L S + R+L +L + + + LDHL ++ E + N+Q+ ++
Sbjct: 1469 QAELEASQKESRSLSTELFKMKNAYEESLDHLQTLKRENK----NLQQEISDLTEQIAEG 1524
Query: 3958 XXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKA 4137
++K +Q+E EK+ + EEAE H E +I + + + +
Sbjct: 1525 GKAIHELEKVK-------KQIEQEKSEIQAALEEAEASLEHEEGKILRLQLELNQVKSEI 1577
Query: 4138 EESV---NQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE-- 4302
+ + ++++++L++ +LR VE LQ L+ ++ L+ KKK++ +L + ++L
Sbjct: 1578 DRKIAEKDEEIDQLKRNHLRIVESLQSSLDAEIRSRNEALRLKKKMEGDLNEMEIQLSHA 1637
Query: 4303 ------------NVRASHRDS---------------------EKRQKKFESQMAEERVAV 4383
N +A +D+ E+R ++++ E R A+
Sbjct: 1638 NRVAAEAQKNLRNTQAVLKDTQIHLDDALRTQEVLKEQVAMVERRANLLQAEIEELRAAL 1697
Query: 4384 QKALLDRDAMSQELRDRETRV-------LSLLN-----EVDI------MKEHLEESDRVR 4509
++ R QEL D RV SL+N E DI M++ ++E+
Sbjct: 1698 EQTERSRKVAEQELMDASERVQLLHTQNTSLINTKKKLETDIAQIQSEMEDTIQEARNTE 1757
Query: 4510 RSLQQELQDSISNKDDFGKNVH---ELEKAKRSLEAELNDMRVQMEELED------NLQI 4662
++ + D+ ++ K LE+ K++L+ + D++ +++E E QI
Sbjct: 1758 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLDQTVKDLQHRLDEAEQLALKGGKKQI 1817
Query: 4663 AE-DARLR-LEVTNQALKSESDRAI----------------SNKDV-------------- 4746
+ +AR+R LE A + S A+ S +D+
Sbjct: 1818 QKLEARVRELEGEVDAEQKRSAEAVKGVRKYERRVKELTYQSEEDLKNILRLQDLVDKLQ 1877
Query: 4747 -----------EAEEKRRGLLKQIRDLENELE-------------NEKRGKSGAVSHRKK 4854
EAEE L + R +++ELE N+ R KS H KK
Sbjct: 1878 MKVKSYKRQAEEAEELSNVNLSKFRKIQHELEEAEERADIAESQVNKLRVKSREF-HSKK 1936
Query: 4855 IENQ 4866
IE +
Sbjct: 1937 IEEE 1940
Score = 128 bits (321), Expect = 2e-27
Identities = 141/756 (18%), Positives = 319/756 (41%), Gaps = 45/756 (5%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + E+ +++ + + +R +LE++ + QE+ D+ ++ S AD ++
Sbjct: 851 EKEMANMKEEFEKTKEELAKSEAKRKELEEKMVKLVQEKNDLQLQVQAEADSLADAEERC 910
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ + +E L + + DE L + ++ E A ++
Sbjct: 911 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDMDDLELTLAKVE 970
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ K A N+ + L +E AL +E +K +
Sbjct: 971 KE---------------------KHATENKVKNLTEEMAAL----DETIVKLTKEKKALQ 1005
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
A Q + + E+ VN L + + K + V+ L+ LE+ + + + ++K+K++ +L
Sbjct: 1006 EAHQQTLDDLQAEEDKVNT-LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDL 1064
Query: 4279 E---DSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL 4449
+ DS M+LEN + D + ++K FE + ++ ++AL + +++++ + R+
Sbjct: 1065 KLAHDSIMDLENDK-QQLDEKLKKKDFEISQIQSKIEDEQAL--GMQLQKKIKELQARIE 1121
Query: 4450 SLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFG-----------KNVHELEKAKR 4596
L E++ + ++++ R L +EL++ ++ G K E +K +R
Sbjct: 1122 ELEEEIEAERTSRAKAEKHRADLSRELEEISERLEEAGGATAAQIDMNKKREAEFQKMRR 1181
Query: 4597 SL-EAELN-------------DMRVQMEELEDNLQIA------EDARLRLEVTNQALKSE 4716
L EA L D ++ E DNLQ E + L++E+ + A E
Sbjct: 1182 DLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNME 1241
Query: 4717 SDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEV 4896
S +S E+ R L Q+ +++ + E +R + + R +++ + GE +Q+E
Sbjct: 1242 S---VSKAKANLEKMCRTLEDQLSEIKTKEEEHQRMINDLNTQRARLQTEAGEYSRQVEE 1298
Query: 4897 ANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA----DRKFRAVEAEREQ 5064
+ L + E + EE +AK +A L+ A D E E+E
Sbjct: 1299 KDALISQLSRGKQAFTQQIEELKRHLEEEIKAKNALAHALQSARHDCDLLREQYEEEQEA 1358
Query: 5065 LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCEL 5244
E L +A + + E K++L ++ + C
Sbjct: 1359 KGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCAS 1418
Query: 5245 AIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARA 5424
+++ Q ++E + D+ + ++++ ++ ++K K E ++ ++ ++
Sbjct: 1419 LEKTKQRLQNEVEDLMIDVERANAACAALDKKQKNFDKILAEWKQKYEETQAELEA-SQK 1477
Query: 5425 QMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEK 5604
+ +L ++ +++ R + L++ ++D T+Q + +A + +++ ++
Sbjct: 1478 ESRSLSTELFKMKNAYEESLDHLQTLKRENKNLQQEISDLTEQIAEGGKAIHELEKVKKQ 1537
Query: 5605 SNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ ++ L+EAE + E K +Q E + +
Sbjct: 1538 IEQEKSEIQAALEEAEASLEHEEGKILRLQLELNQV 1573
Score = 99.4 bits (246), Expect = 1e-18
Identities = 121/627 (19%), Positives = 268/627 (42%), Gaps = 59/627 (9%)
Frame = +1
Query: 3055 ERAKHGVKAKGRLENQLHELEQDLNRER--------QYKSELEQHKRKLLAELEDSKDHL 3210
E+ + +AKG L+ L + ++ + R Q ELE+ K+KL L+D+++H+
Sbjct: 1350 EQYEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHV 1409
Query: 3211 AEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETER 3390
K L + E++ + + +A + K+ ++ + E ++ E +
Sbjct: 1410 EAVNAKCASLEKTKQRLQNEVEDLMIDVERANAACAALDKKQKNFDKILAEWKQKYEETQ 1469
Query: 3391 NARNKAEMTRREVVAQLEKVKGDVLDKVD-------EATMLQDLMSRKDEEVNATKRAIE 3549
++ R + +L K+K + +D E LQ +S E++ +AI
Sbjct: 1470 AELEASQKESRSLSTELFKMKNAYEESLDHLQTLKRENKNLQQEISDLTEQIAEGGKAIH 1529
Query: 3550 QIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQ 3729
+++ + +IE++K++ +EE +E + + +L+ + NQ ++++ ++IA
Sbjct: 1530 ELEKVKK-QIEQEKSEIQAALEEAEASLEHEEGKILRLQLELNQV---KSEIDRKIA--- 1582
Query: 3730 ASRADIDKKRKIHEAHLMEIQANLA-------ESDEHKRTLIDQLERSRDELDHLNRVRE 3888
+ID+ ++ H + +Q++L E+ K+ + L +L H NRV
Sbjct: 1583 EKDEEIDQLKRNHLRIVESLQSSLDAEIRSRNEALRLKKKMEGDLNEMEIQLSHANRVAA 1642
Query: 3889 EEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKE---- 4056
E + N Q L T++ + + R +++ E+ A+++ +
Sbjct: 1643 EAQKNLRNTQAVLKD---------------TQIHLDDALRTQEVLKEQVAMVERRANLLQ 1687
Query: 4057 -EAEGLRAHLEKEIHAARQGAGEARRKAEESV------NQQLEELRKKNLRDVEHLQKQL 4215
E E LRA LE + +R+ A + A E V N L +KK D+ +Q ++
Sbjct: 1688 AEIEELRAALE-QTERSRKVAEQELMDASERVQLLHTQNTSLINTKKKLETDIAQIQSEM 1746
Query: 4216 EESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKAL 4395
E++ + +++K ++ + D++M E ++ +D+ ++ + + + +Q L
Sbjct: 1747 EDTI---QEARNTEEKAKKAITDAAMMAEELK-KEQDTSAHLERMKKNLDQTVKDLQHRL 1802
Query: 4396 LDRDAMS-----QELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDF 4560
+ + ++ ++++ E RV L EVD ++ E+ + R ++ +++ ++
Sbjct: 1803 DEAEQLALKGGKKQIQKLEARVRELEGEVDAEQKRSAEAVKGVRKYERRVKELTYQSEED 1862
Query: 4561 GKNVHELEKAKRSLEAELNDMRVQ---------------------MEELEDNLQIAEDAR 4677
KN+ L+ L+ ++ + Q +EE E+ IAE
Sbjct: 1863 LKNILRLQDLVDKLQMKVKSYKRQAEEAEELSNVNLSKFRKIQHELEEAEERADIAESQV 1922
Query: 4678 LRLEVTNQALKSESDRAISNKDVEAEE 4758
+L V R +K +E EE
Sbjct: 1923 NKLRV--------KSREFHSKKIEEEE 1941
Score = 71.6 bits (174), Expect = 2e-10
Identities = 106/504 (21%), Positives = 199/504 (39%), Gaps = 11/504 (2%)
Frame = +1
Query: 4264 IQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQK---ALLDRDAMSQELRDR 4434
+++E E + EL A ++ E++ K + + ++ VQ +L D + +L
Sbjct: 857 MKEEFEKTKEELAKSEAKRKELEEKMVKLVQEKNDLQLQVQAEADSLADAEERCDQLIKT 916
Query: 4435 ETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSIS----NKDDFGKNVHELEKAKRSL 4602
+ ++ + + EV E EE + + +++L+D S + DD + ++EK K +
Sbjct: 917 KIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDMDDLELTLAKVEKEKHAT 976
Query: 4603 EAELNDMRVQMEELEDNLQIAEDARLRLEVTNQA----LKSESDRAISNKDVEAEEKRRG 4770
E ++ ++ +M L++ + + L+ +Q L++E D+ N +A+ K
Sbjct: 977 ENKVKNLTEEMAALDETIVKLTKEKKALQEAHQQTLDDLQAEEDKV--NTLTKAKTK--- 1031
Query: 4771 LLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXX 4950
L +Q+ DLE LE EK+ R +E +LE L++A+ +
Sbjct: 1032 LEQQVDDLEGSLEQEKK-------LRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDEK 1084
Query: 4951 XXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXX 5130
+ E + + ED AL + +K + ++A E+L E E
Sbjct: 1085 LKKKDFEISQIQSKIEDEQALGMQLQKKIKELQARIEELEEEIEA--------------E 1130
Query: 5131 XXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSME 5310
RAK ++ R LE + +LE+ + +
Sbjct: 1131 RTSRAKAEKHRADLSRELE-------------------------EISERLEEAGGATAAQ 1165
Query: 5311 RTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQE 5490
+N+K EAE Q + R +LE A + A AAL K D G++
Sbjct: 1166 IDMNKKREAEFQKMRR----------DLEE-ATLQHEATAAALRKK---HADSTAELGEQ 1211
Query: 5491 KTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRE 5670
R ++LEK ++ + +D +E + NL + ED++S
Sbjct: 1212 IDNLQRVKQKLEKEKSELKMEIDD-------LASNMESVSKAKANLEKMCRTLEDQLSEI 1264
Query: 5671 RTKHRNVQREADDLLDANEQLTRE 5742
+TK QR +DL +L E
Sbjct: 1265 KTKEEEHQRMINDLNTQRARLQTE 1288
Score = 52.0 bits (123), Expect = 2e-04
Identities = 65/365 (17%), Positives = 138/365 (37%), Gaps = 1/365 (0%)
Frame = +1
Query: 4654 LQIAEDARLRLEVTNQALKSESDRAISN-KDVEAEEKRRGLLKQIRDLENELENEKRGKS 4830
L+ AE + + + K++ + A S K E EEK L+++ DL+ +++ E +
Sbjct: 845 LKSAESEKEMANMKEEFEKTKEELAKSEAKRKELEEKMVKLVQEKNDLQLQVQAEADSLA 904
Query: 4831 GAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAA 5010
A ++ +LE +++ E+ + + EC E ++ +D+
Sbjct: 905 DAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDMDDLEL 964
Query: 5011 LLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEA 5190
L + +++ A E + + L E L + + ++EK+ L+
Sbjct: 965 TLAKVEKEKHATENKVKNLTEEMAALDETIVKL------------------TKEKKALQE 1006
Query: 5191 KIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRD 5370
Q + + K + Q++ + L E+ L E K+ LE
Sbjct: 1007 AHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLE----- 1061
Query: 5371 YKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQ 5550
G A + LE Q L+++L ++ + ++
Sbjct: 1062 ----------GDLKLAHDSIMDLENDKQQLDEKL--------------KKKDFEISQIQS 1097
Query: 5551 QFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQ 5730
+ EDE+ Q ++ K + L+ +++E E+E+ ERT ++ DL E+
Sbjct: 1098 KIEDEQALGMQLQK-------KIKELQARIEELEEEIEAERTSRAKAEKHRADLSRELEE 1150
Query: 5731 LTREL 5745
++ L
Sbjct: 1151 ISERL 1155
>gi|11342672|ref|NP_002461.1| myosin, heavy polypeptide 3, skeletal
muscle, embryonic [Homo sapiens]
gi|88201|pir||S04090 myosin heavy chain 3, skeletal muscle, embryonic
- human
gi|34844|emb|CAA32167.1| unnamed protein product [Homo sapiens]
Length = 1940
Score = 1127 bits (2916), Expect = 0.0
Identities = 658/1890 (34%), Positives = 1052/1890 (54%), Gaps = 15/1890 (0%)
Frame = +1
Query: 85 CWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTY 264
C+V D E + G IK + +V VE D +R + + +DV NPPKFD+IEDM+ LT+
Sbjct: 38 CFVVDSKEEYAKGKIKSSQDGKVTVETED-NRTLVVKPEDVYAMNPPKFDRIEDMAMLTH 96
Query: 265 LNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIF 444
LNE +VL+NLKDRY S +IYTYSGLFCV +NPYK LP+Y+ +++E ++GKKR E PPHIF
Sbjct: 97 LNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIF 156
Query: 445 AIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNI 624
+I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A + AA ++
Sbjct: 157 SISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATI-----------AATGDL 205
Query: 625 VQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANI 804
+K D + G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+I
Sbjct: 206 AKKKDSKMK-GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADI 264
Query: 805 EFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPN 978
E YLLEKSRV Q + ERS+HIFYQIL E E LL + +Y F+ I + +
Sbjct: 265 ETYLLEKSRVTFQLKAERSYHIFYQILSN-KKPELIELLLITTNPYDYPFISQGEILVAS 323
Query: 979 VDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQ 1158
+DD +E +T +++ I+GF +E S + ++ AV+ GN++F Q+++ +QA V
Sbjct: 324 IDDREELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVAD 383
Query: 1159 KVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTR 1338
K +L+GL +L KA PR+KVG E+V K Q +Q AV A++K+ YE+LF W+VTR
Sbjct: 384 KTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTR 443
Query: 1339 INKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEY 1518
IN+ LD T FIG+LDIAGFEIF+ NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY
Sbjct: 444 INQQLD-TKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 502
Query: 1519 QREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH----N 1686
++EGIEW FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H N
Sbjct: 503 KKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSN 562
Query: 1687 KHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIW 1866
K V R+++HF+++HYAG VDYS WL KN DPLNE VVGL Q S++ +A +
Sbjct: 563 NFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHL- 621
Query: 1867 KDAEFAGICAAEMNETAFGMRSRKG-MFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPN 2043
+A A+ + + +KG F+TVS L +E L KLM+ LR T PHFVRCIIPN
Sbjct: 622 ----YATFATADADSGKKKVAKKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPN 677
Query: 2044 HEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPD-VIPKNFI 2220
K G + +LVL QLRCNGVLEGIRICR+GFPNR+ + +F+ RY +L ++ FI
Sbjct: 678 ETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAILEGQFI 737
Query: 2221 DGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFL 2400
D K++ K++ ++DID Y+ G +KVFF+ G+L LEE RD +L LI QA CRGFL
Sbjct: 738 DSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGFL 797
Query: 2401 SRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDEL 2580
R + N +++ +++W W +LF K+KPLL+ T+ E+ +E
Sbjct: 798 MRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEF 857
Query: 2581 RATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELE 2760
+ TK+ L K E +E E+KL ++ E+ +Q Q+Q ESEN + ++ +L +LE
Sbjct: 858 QKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLE 917
Query: 2761 YIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXX 2940
+ ++ +R +RK + + +K +
Sbjct: 918 AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 977
Query: 2941 XXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQ 3120
+ L E++ K K +LE Q+ +LE
Sbjct: 978 NLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLES 1037
Query: 3121 DLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDE 3300
L +E++ + +LE++KRKL +L+ +++ + + ++L+ +L K+D E ++ ++
Sbjct: 1038 SLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVED 1097
Query: 3301 ESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDE 3480
E QK+++++Q I+EL E++E ER R K E R + +LE++ + L++
Sbjct: 1098 EQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEEL-SERLEEAGG 1156
Query: 3481 ATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRS 3657
T Q +L +++ E +R +E+ E + + K + V EL +QI+ ++ +
Sbjct: 1157 VTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQ 1216
Query: 3658 QLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLID 3837
+LEK++++ E D++ + + S+A+++K + E L E + E L
Sbjct: 1217 KLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTT 1276
Query: 3838 QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQ 4017
Q R + E L+R EE+E + + R + K A + +
Sbjct: 1277 QKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQS 1336
Query: 4018 LEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVE 4197
+ + L ++ EE + +A L++ + A + R K E Q+ EEL + + +
Sbjct: 1337 SRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAQEKLAQ 1396
Query: 4198 HLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAE 4368
LQ E+ E + + ++K+++Q E+ED +++E + +K+Q+ F+ +AE
Sbjct: 1397 RLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAE 1456
Query: 4369 ERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISN 4548
+ +++ + +A +E R T + L N + + LE R ++L+QE+ D
Sbjct: 1457 WKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQ 1516
Query: 4549 KDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRA 4728
+ GK +HELEK+++ +E E D+++ +EE E L+ E LR+++ +KSE DR
Sbjct: 1517 IAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRK 1576
Query: 4729 ISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRL 4908
I+ KD E E+ +R + + +++ L+ E R ++ A+ +KK+E + E+E QL ANR
Sbjct: 1577 IAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQ 1636
Query: 4909 KEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGL 5088
E + Q+ ++A + +ED+ L +R+ ++AE E+LR E
Sbjct: 1637 AAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQT 1696
Query: 5089 MQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQ 5259
+ARK Q K++LE + Q + A +K
Sbjct: 1697 ERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKA 1756
Query: 5260 RKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAAL 5439
+KA + +L E+ + E K++LE++ +D + ++ E E A + Q+ L
Sbjct: 1757 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1816
Query: 5440 EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKN 5619
E +++ LE +L E ++ T + + R+ E+R+ + T Q E++++ + ++L++K +K
Sbjct: 1817 ETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKV 1876
Query: 5620 RNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
++ +RQ +EA+++ + TK R Q E ++
Sbjct: 1877 KSYKRQAEEADEQANAHLTKFRKAQHELEE 1906
Score = 77.0 bits (188), Expect = 5e-12
Identities = 105/527 (19%), Positives = 215/527 (39%), Gaps = 16/527 (3%)
Frame = +1
Query: 4213 LEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQ-- 4386
L+ +E KE +++E + + EL A ++ E++ + + ++ VQ
Sbjct: 841 LKSAETEKEMAT-----MKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAE 895
Query: 4387 -KALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFG 4563
+ LLD + +L + ++ + + EV E EE + + +++L+D S +
Sbjct: 896 SENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECS---ELK 952
Query: 4564 KNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
K++ +LE +E E + +++ L + L ++ +L +AL+ +A+ D
Sbjct: 953 KDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALD--D 1010
Query: 4744 VEAEEKRRGLL--------KQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
++AEE + L +Q+ DLE+ LE EK+ + +++K+E + ++ +
Sbjct: 1011 LQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDL 1070
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREAN 5079
K++ + Q + E+ + ++E + +E E E R
Sbjct: 1071 ENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATR 1130
Query: 5080 EGLMQARKQXXXXXXXXXXXRAKGGGISSEE-----KRRLEAKIAQXXXXXXXXQSNCEL 5244
+ R + GG++S + KR E + Q +
Sbjct: 1131 AKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMV 1190
Query: 5245 AIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARA 5424
A +++ A E +++R KQ LE+ ++K +I +L S +S +++
Sbjct: 1191 ATLRKKHADSVAELGEQIDNLQRV--------KQKLEKEKSEFKLEIDDLSSSMESVSKS 1242
Query: 5425 QMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEK 5604
+ A LE + LEDQL+ A +++ L++ T Q + R +A EL
Sbjct: 1243 K-ANLEKICRTLEDQLS-------EARGKNEEIQRSLSELTTQ---KSRLQTEAGEL--- 1288
Query: 5605 SNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
RQL+E E +S+ + R E+L R+L
Sbjct: 1289 --------SRQLEEKESIVSQ-------LSRSKQAFTQQTEELKRQL 1320
>gi|86355|pir||JX0178 myosin heavy chain, fast skeletal muscle, adult
[validated] - chicken
gi|238274|gb|AAB20215.1| myosin heavy chain [chickens, skeletal
muscle, Peptide, 1938 aa]
Length = 1938
Score = 1127 bits (2914), Expect = 0.0
Identities = 657/1888 (34%), Positives = 1056/1888 (55%), Gaps = 14/1888 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V E F+ G+I+ + +V V+ + +T+ D V NPPK+DKIEDM+ +T+L
Sbjct: 39 FVVHPKESFVKGTIQSKEGGKVTVK-TEGGETLTVKEDQVFSMNPPKYDKIEDMAMMTHL 97
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 98 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVLAYRGKKRQEAPPHIFS 157
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A + K + +
Sbjct: 158 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAASGEKKKEEQSGKMQ-- 215
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 216 ---------GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIE 266
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPNV 981
YLLEKSRV Q ERS+HIFYQI+ E + LL + +Y ++ IT+P++
Sbjct: 267 TYLLEKSRVTFQLPAERSYHIFYQIMSN-KKPELIDMLLITTNPYDYHYVSQGEITVPSI 325
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
DD +E +T +++ I+GF+ DE ++I ++ AV+ GNL+F Q+++ +QA V K
Sbjct: 326 DDQEELMATDSAIDILGFSADEKTAIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADK 385
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L+GL EL KA PR+KVG EFV K Q Q +V A+AKA YE++F W+V RI
Sbjct: 386 AAYLMGLNSAELLKALCYPRVKVGNEFVTKGQTVSQVHNSVGALAKAVYEKMFLWMVIRI 445
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 446 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYK 504
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H K
Sbjct: 505 KEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNN 564
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P ++++HF++VHYAG VDY+ WL KN DPLNE V+GL Q S+ +A ++
Sbjct: 565 FQKPKPAKGKAEAHFSLVHYAGTVDYNISGWLEKNKDPLNETVIGLYQKSSVKTLALLF- 623
Query: 1870 DAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHE 2049
A + G AE G + + F+TVS L +E L KLM LR+T PHFVRCIIPN
Sbjct: 624 -ATYGG--EAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMANLRSTHPHFVRCIIPNET 680
Query: 2050 KKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDG 2226
K G + LVL QLRCNGVLEGIRICR+GFP+RV + +F+ RY +L IP+ F+D
Sbjct: 681 KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRVLYADFKQRYRVLNASAIPEGQFMDS 740
Query: 2227 KESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSR 2406
K++ K++ ++D+D YR G +KVFF+ G+L LEE RD KL +I QA+CRGFL R
Sbjct: 741 KKASEKLLGSIDVDHTQYRFGHTKVFFKAGLLGLLEEMRDDKLAEIITRTQARCRGFLMR 800
Query: 2407 RLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRA 2586
Y N +++ +++W W +LF K+KPLL+ ++ E+ +E
Sbjct: 801 VEYRRMVERRESIFCIQYNVRSFMNVKHWPWMKLFFKIKPLLKSAESEKEMANMKEEFEK 860
Query: 2587 TKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYI 2766
TKE L K E +E E+K+ ++ E+ +Q Q+Q E+++ A+ ++ +L +LE
Sbjct: 861 TKEELAKSEAKRKELEEKMVVLLQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAK 920
Query: 2767 VNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXX 2946
+ ++ +R +RK + + +K +
Sbjct: 921 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 980
Query: 2947 XXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDL 3126
+ L E++ KAK +LE Q+ +LE L
Sbjct: 981 TEEMAVLDETIAKLTKEKKALQEAHQQTLDDLQVEEDKVNTLTKAKTKLEQQVDDLEGSL 1040
Query: 3127 NRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEES 3306
+E++ + +LE+ KRKL +L+ + D + + ++L+ +L K+D E+ ++ ++E
Sbjct: 1041 EQEKKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQ 1100
Query: 3307 ANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT 3486
A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L++ AT
Sbjct: 1101 ALGMQLQKKIKELQARIEELEEEIEAERTSRAKAEKHRADLSRELEEI-SERLEEAGGAT 1159
Query: 3487 MLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQL 3663
Q M++K E E +R +E+ E + K + EL +QI+ ++ + +L
Sbjct: 1160 AAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKL 1219
Query: 3664 EKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQL 3843
EK++++ E D+A + + ++A+++K + E L EI+ ++ L Q
Sbjct: 1220 EKEKSELKMEIDDLASNMESVSKAKANLEKMCRTLEDQLSEIKTKEEQNQRMINDLNTQR 1279
Query: 3844 ERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLE 4023
R + E +R EE++ + + R + K A + +
Sbjct: 1280 ARLQTETGEYSRQAEEKDALISQLSRGKQGFTQQIEELKRHLEEEIKAKNALAHALQSAR 1339
Query: 4024 DEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHL 4203
+ + L ++ EE + + L++ + A + R K E Q+ EEL + + + L
Sbjct: 1340 HDCDLLREQYEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1399
Query: 4204 QKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEER 4374
Q E E + + ++K+++Q E+ED +++E A+ +K+QK F+ +AE +
Sbjct: 1400 QDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMVDVERSNAACAALDKKQKNFDKILAEWK 1459
Query: 4375 VAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKD 4554
++ + +A +E R T + + N + +HLE R ++LQQE+ D
Sbjct: 1460 QKYEETQTELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEIADLTEQIA 1519
Query: 4555 DFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAIS 4734
+ GK VHELEK K+ +E E ++++ +EE E +L+ E LRL++ +KSE DR I+
Sbjct: 1520 EGGKAVHELEKVKKHVEQEKSELQAALEEAEASLEHEEGKILRLQLELNQIKSEIDRKIA 1579
Query: 4735 NKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKE 4914
KD E ++ +R L+ + +++ L+ E R ++ A+ +KK+E + E+E QL ANR+
Sbjct: 1580 EKDEEIDQLKRNHLRIVESMQSTLDAEIRSRNEALRLKKKMEGDLNEMEIQLSHANRMAA 1639
Query: 4915 EYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQ 5094
E + QI ++A + +ED+ + +R+ ++AE E+LR A E +
Sbjct: 1640 EAQKNLRNTQGTLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEVEELRGALEQTER 1699
Query: 5095 ARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRK 5265
+RK Q K++LE I Q A +K +K
Sbjct: 1700 SRKVAEQELLDATERVQLLHTQNTSLINTKKKLETDIVQIQSEMEDTIQEARNAEEKAKK 1759
Query: 5266 AQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEA 5445
A + +L E+ + E K++++++ +D + ++ E E A + Q+ LEA
Sbjct: 1760 AITDAAMMAEELKKEQDTSAHLERMKKNMDQTVKDLQLRLDEAEQLALKGGKKQLQKLEA 1819
Query: 5446 KVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRN 5625
+V+ LE +++ E + A + R+ E+R+ + T Q E++++ + ++L++K +K ++
Sbjct: 1820 RVRELEGEVDAEQKRSAEAVKGVRKYERRVKELTYQCEEDRKNILRLQDLVDKLQMKVKS 1879
Query: 5626 LRRQLDEAEDEMSRERTKHRNVQREADD 5709
+RQ +EAE+ + +K R +Q E ++
Sbjct: 1880 YKRQAEEAEELSNVNLSKFRKIQHELEE 1907
Score = 163 bits (413), Expect = 4e-38
Identities = 188/922 (20%), Positives = 383/922 (41%), Gaps = 36/922 (3%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + + +++L + + ELE+ LL E D + + A+ + EE +
Sbjct: 849 KEMANMKEEFEKTKEELAKSEAKRKELEEKMVVLLQEKNDLQLQVQAEADSLADAEERCD 908
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE N L K+ R ++ EL++D++ E
Sbjct: 909 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKDIDD-------LE 960
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQ------IQHTMEG 3573
+T +V + + V + +E +L + +++ +E A + A +Q ++
Sbjct: 961 LTLAKVEKEKHATENKVKNLTEEMAVLDETIAKLTKEKKALQEAHQQTLDDLQVEEDKVN 1020
Query: 3574 KIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK 3753
+ + K K +QV++L +EQ KK R LE+ + + + + I L+ + +D+
Sbjct: 1021 TLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDE 1080
Query: 3754 KRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLAT 3933
K K + + +IQ+ + E ++ L QL++ EL R+ E EE A R
Sbjct: 1081 KLKKKDFEISQIQSKI----EDEQALGMQLQKKIKELQ--ARIEELEEEIEAERTSRAKA 1134
Query: 3934 AXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQG 4113
RL+ A A Q+E +++K EAE
Sbjct: 1135 EKHRADLSRELEEISERLEEAGGATAAQIE------MNKKREAE---------------- 1172
Query: 4114 AGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELED 4284
+ RR EE+ Q LRKK+ L +Q++ + K+++ + K +++ E++D
Sbjct: 1173 FQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDD 1232
Query: 4285 SSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNE 4464
+ +E+V + + EK + E Q++E + + + + D T+ L E
Sbjct: 1233 LASNMESVSKAKANLEKMCRTLEDQLSEIKT-------KEEQNQRMINDLNTQRARLQTE 1285
Query: 4465 VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEEL 4644
EE D + L + Q ++ +++ E KAK +L L R + L
Sbjct: 1286 TGEYSRQAEEKDALISQLSRGKQGFTQQIEELKRHLEEEIKAKNALAHALQSARHDCDLL 1345
Query: 4645 EDNLQIAEDARLRL---------EVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLE 4797
+ + ++A+ L EV K E+D AI + E EE ++ L ++++D E
Sbjct: 1346 REQYEEEQEAKGELQRALSKANSEVAQWRTKYETD-AIQRTE-ELEEAKKKLAQRLQDAE 1403
Query: 4798 NELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECE 4977
+E + +++++N++ +L +E +N E++ + E
Sbjct: 1404 EHVEAVNAKCASLEKTKQRLQNEVEDLMVDVERSNAACAALDKKQKNFDKILAEWKQKYE 1463
Query: 4978 EARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGG 5157
E + E R + ++ E+ + E L + K A+GG
Sbjct: 1464 ETQTELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEIADLTEQIAEGGK 1523
Query: 5158 ISSE---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQK 5328
E K+ +E + ++ +++ E K + Q++L QI ++ +++K
Sbjct: 1524 AVHELEKVKKHVEQEKSELQAALEEAEASLEHEEGKILRLQLELNQIKSE------IDRK 1577
Query: 5329 TEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANR 5508
+ + +++ R++ + ++S + R++ AL K + +E LN + + ANR
Sbjct: 1578 IAEKDEEIDQLKRNHLRIVESMQSTLDAEIRSRNEALRLK-KKMEGDLNEMEIQLSHANR 1636
Query: 5509 AARRLEKR-------LNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSR 5667
A +K L DT +D R E KE + + L+ +++E + +
Sbjct: 1637 MAAEAQKNLRNTQGTLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEVEELRGALEQ 1696
Query: 5668 ERTKHRNVQREADDLLDANEQL 5733
+ ++E LLDA E++
Sbjct: 1697 TERSRKVAEQE---LLDATERV 1715
Score = 133 bits (335), Expect = 5e-29
Identities = 175/905 (19%), Positives = 365/905 (39%), Gaps = 136/905 (15%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ + ++ +E+D ++ ++KL + E + IQ +++ E +L LQ
Sbjct: 1055 RKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQ 1114
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + +R S R ++E + + +
Sbjct: 1115 ARIEELEEEIE--AERTSRAKAEKHRADLSR--ELEEISERLEEAGGATAAQIEMNKKRE 1170
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K L+
Sbjct: 1171 AEFQKMRRDLEEATLQHEATAAALRKKHADSTAELG---EQIDNLQRVKQKLEKEKSELK 1227
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K+ LE+ R L +L + K + + +LN Q + E
Sbjct: 1228 MEIDDLASNMESVSKAKANLEKMCRTLEDQLSEIKTKEEQNQRMINDLNTQRARLQTETG 1287
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ +E+ A ++ + + + I+EL+ +E E A+N + + ++
Sbjct: 1288 EYSRQAEEKDALISQLSRGKQGFTQQIEELKRHLEEEIKAKNALAHALQSARHDCDLLRE 1347
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
++ + LQ +S+ + EV TK + IQ T E +EE K K ++++++ +
Sbjct: 1348 QYEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQDAEEH 1405
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME-------I 3789
+E + + LEK + + E D+ ++ A+ A +DKK+K + L E
Sbjct: 1406 VEAVNAKCASLEKTKQRLQNEVEDLMVDVERSNAACAALDKKQKNFDKILAEWKQKYEET 1465
Query: 3790 QANLAESDEHKRTLIDQLERSR----DELDHLNRVREEEEHAFANMQRRLATAXXXXXXX 3957
Q L S + R+L +L + + + LDHL ++ E + N+Q+ +A
Sbjct: 1466 QTELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENK----NLQQEIADLTEQIAEG 1521
Query: 3958 XXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKA 4137
++K + +E EK+ L EEAE H E +I + + + +
Sbjct: 1522 GKAVHELEKVK-------KHVEQEKSELQAALEEAEASLEHEEGKILRLQLELNQIKSEI 1574
Query: 4138 EESV---NQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE-- 4302
+ + ++++++L++ +LR VE +Q L+ ++ L+ KKK++ +L + ++L
Sbjct: 1575 DRKIAEKDEEIDQLKRNHLRIVESMQSTLDAEIRSRNEALRLKKKMEGDLNEMEIQLSHA 1634
Query: 4303 ------------NVRASHRDS---------------------EKRQKKFESQMAEERVAV 4383
N + + +D+ E+R ++++ E R A+
Sbjct: 1635 NRMAAEAQKNLRNTQGTLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEVEELRGAL 1694
Query: 4384 QKALLDRDAMSQELRDRETRV-------LSLLN-----EVDIMKEHLEESDRVR--RSLQ 4521
++ R QEL D RV SL+N E DI++ E D ++ R+ +
Sbjct: 1695 EQTERSRKVAEQELLDATERVQLLHTQNTSLINTKKKLETDIVQIQSEMEDTIQEARNAE 1754
Query: 4522 QELQDSISN--------KDDFGKNVHELEKAKRSLEAELNDMRVQMEELED-NLQIAEDA 4674
++ + +I++ K + + H LE+ K++++ + D++++++E E L+ +
Sbjct: 1755 EKAKKAITDAAMMAEELKKEQDTSAH-LERMKKNMDQTVKDLQLRLDEAEQLALKGGKKQ 1813
Query: 4675 RLRLEVTNQALKSESD-----------------RAISNKDVEAEEKRRGLLK-------- 4779
+LE + L+ E D R + + EE R+ +L+
Sbjct: 1814 LQKLEARVRELEGEVDAEQKRSAEAVKGVRKYERRVKELTYQCEEDRKNILRLQDLVDKL 1873
Query: 4780 -----------------------QIRDLENELE-------------NEKRGKSGAVSHRK 4851
+ R +++ELE N+ R KS + H K
Sbjct: 1874 QMKVKSYKRQAEEAEELSNVNLSKFRKIQHELEEAEERADIAESQVNKLRVKSREI-HGK 1932
Query: 4852 KIENQ 4866
KIE +
Sbjct: 1933 KIEEE 1937
Score = 127 bits (318), Expect = 4e-27
Identities = 147/760 (19%), Positives = 314/760 (40%), Gaps = 49/760 (6%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + E+ +++ + + +R +LE++ QE+ D+ ++ S AD ++
Sbjct: 848 EKEMANMKEEFEKTKEELAKSEAKRKELEEKMVVLLQEKNDLQLQVQAEADSLADAEERC 907
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ + +E L + + DE L + ++ E A ++
Sbjct: 908 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 967
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ T K+ N+ + DE A L ++++A +
Sbjct: 968 KE---------------KHATENKVKNLTEEMAVLDETIAKLTKEKKA----------LQ 1002
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
A Q + + E+ VN L + + K + V+ L+ LE+ + + + ++K+K++ +L
Sbjct: 1003 EAHQQTLDDLQVEEDKVNT-LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDL 1061
Query: 4279 E---DSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL 4449
+ DS M+LEN + D + ++K FE + ++ ++AL + +++++ + R+
Sbjct: 1062 KLAHDSIMDLENDK-QQLDEKLKKKDFEISQIQSKIEDEQAL--GMQLQKKIKELQARIE 1118
Query: 4450 SLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFG-----------KNVHELEKAKR 4596
L E++ + ++++ R L +EL++ ++ G K E +K +R
Sbjct: 1119 ELEEEIEAERTSRAKAEKHRADLSRELEEISERLEEAGGATAAQIEMNKKREAEFQKMRR 1178
Query: 4597 SL-EAELN-------------DMRVQMEELEDNLQIA------EDARLRLEVTNQALKSE 4716
L EA L D ++ E DNLQ E + L++E+ + A E
Sbjct: 1179 DLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNME 1238
Query: 4717 SDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEV 4896
S +S E+ R L Q+ +++ + E +R + + R +++ + GE +Q E
Sbjct: 1239 S---VSKAKANLEKMCRTLEDQLSEIKTKEEQNQRMINDLNTQRARLQTETGEYSRQAEE 1295
Query: 4897 ANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA----DRKFRAVEAEREQ 5064
+ L + E + EE +AK +A L+ A D E E+E
Sbjct: 1296 KDALISQLSRGKQGFTQQIEELKRHLEEEIKAKNALAHALQSARHDCDLLREQYEEEQEA 1355
Query: 5065 LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCEL 5244
E L +A + + E K++L ++ + C
Sbjct: 1356 KGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCAS 1415
Query: 5245 AIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKI----TELESGAQS 5412
+++ Q ++E + D+ + ++++ ++ ++K K TELE+ +
Sbjct: 1416 LEKTKQRLQNEVEDLMVDVERSNAACAALDKKQKNFDKILAEWKQKYEETQTELEASQKE 1475
Query: 5413 RARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKE 5592
+ K Y E ++E R + L++ + D T+Q + +A + ++
Sbjct: 1476 SRSLSTELFKMKNAYEESLDHLE-----TLKRENKNLQQEIADLTEQIAEGGKAVHELEK 1530
Query: 5593 LLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ + + L+ L+EAE + E K +Q E + +
Sbjct: 1531 VKKHVEQEKSELQAALEEAEASLEHEEGKILRLQLELNQI 1570
Score = 70.5 bits (171), Expect = 5e-10
Identities = 104/519 (20%), Positives = 196/519 (37%), Gaps = 16/519 (3%)
Frame = +1
Query: 4234 KERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAM 4413
K + L + ++E+ + E E + SE ++K+ E +M L A
Sbjct: 837 KIKPLLKSAESEKEMANMKEEFEKTKEELAKSEAKRKELEEKMVVLLQEKNDLQLQVQAE 896
Query: 4414 SQELRDRETRVLSLLN-------EVDIMKEHLEESDRVRRSL---QQELQDSISNKDDFG 4563
+ L D E R L+ ++ + E E+ + + L +++L+D S +
Sbjct: 897 ADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECS---ELK 953
Query: 4564 KNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
K++ +LE +E E + +++ L + + + ++ +L +AL+ + + +
Sbjct: 954 KDIDDLELTLAKVEKEKHATENKVKNLTEEMAVLDETIAKLTKEKKALQEAHQQTLDDLQ 1013
Query: 4744 VEAEE------KRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANR 4905
VE ++ + L +Q+ DLE LE EK+ R +E +LE L++A+
Sbjct: 1014 VEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKK-------LRMDLERAKRKLEGDLKLAHD 1066
Query: 4906 LKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEG 5085
+ + E + + ED AL + +K + ++A E+L E E
Sbjct: 1067 SIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQARIEELEEEIEA 1126
Query: 5086 LMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRK 5265
RAK ++ R LE +
Sbjct: 1127 --------------ERTSRAKAEKHRADLSRELE-------------------------E 1147
Query: 5266 AQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEA 5445
+LE+ + + +N+K EAE Q + R +LE A + A AAL
Sbjct: 1148 ISERLEEAGGATAAQIEMNKKREAEFQKMRR----------DLEE-ATLQHEATAAALRK 1196
Query: 5446 KVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRN 5625
K D G++ R ++LEK ++ + +D +E + N
Sbjct: 1197 K---HADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDD-------LASNMESVSKAKAN 1246
Query: 5626 LRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
L + ED++S +TK QR +DL +L E
Sbjct: 1247 LEKMCRTLEDQLSEIKTKEEQNQRMINDLNTQRARLQTE 1285
Score = 54.7 bits (130), Expect = 3e-05
Identities = 78/349 (22%), Positives = 134/349 (38%), Gaps = 51/349 (14%)
Frame = +1
Query: 4852 KIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADR 5031
KI+ + E + E+AN +KEE+ + ++ +E + LL+E +
Sbjct: 837 KIKPLLKSAESEKEMAN-MKEEFEKTKEELAKSEAK-------RKELEEKMVVLLQEKND 888
Query: 5032 KFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXX 5211
V+AE + L +A E Q K K +LEAKI +
Sbjct: 889 LQLQVQAEADSLADAEERCDQLIKT----------------------KIQLEAKIKEVTE 926
Query: 5212 XXXXXQS-NCELAIDKQRKAQVQLEQITTDLS-MERTLNQKTEAEKQSLERSNRDYKAKI 5385
+ N EL K+RK + + ++ D+ +E TL K E EK + E ++ ++
Sbjct: 927 RAEDEEEINAELTA-KKRKLEDECSELKKDIDDLELTL-AKVEKEKHATENKVKNLTEEM 984
Query: 5386 TELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDE 5565
L+ + + A EA Q L+D L VE + +A +LE++++D E E
Sbjct: 985 AVLDETIAKLTKEKKALQEAHQQTLDD-LQVEEDKVNTLTKAKTKLEQQVDDLEGSLEQE 1043
Query: 5566 KRAN---EQAKELLE----------------KSNL------------------------- 5613
K+ E+AK LE K L
Sbjct: 1044 KKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALG 1103
Query: 5614 -----KNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
K + L+ +++E E+E+ ERT ++ DL E+++ L
Sbjct: 1104 MQLQKKIKELQARIEELEEEIEAERTSRAKAEKHRADLSRELEEISERL 1152
>gi|21907898|dbj|BAC05679.1| myosin heavy chain 2a [Equus caballus]
Length = 1937
Score = 1126 bits (2912), Expect = 0.0
Identities = 656/1888 (34%), Positives = 1058/1888 (55%), Gaps = 14/1888 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V + E F+ G+I+ +V V+ D +T+ D V NPPK+DKIEDM+ +T+L
Sbjct: 39 FVAEPKESFVKGTIQSREGGKVTVK-TDAGATLTVKEDQVFPMNPPKYDKIEDMAMMTHL 97
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 98 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFS 157
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A K Q
Sbjct: 158 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEPGKMQ--- 214
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 215 ---------GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIE 265
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRF-LVNRG-ITLPNV 981
YLLEKSRV Q + ERS+HIFYQI E E LL + Y + V++G I++ ++
Sbjct: 266 TYLLEKSRVTFQLKAERSYHIFYQITSN-RKPELIEMLLITTNPYDYPYVSQGEISVASI 324
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
DD +E +T +++ I+GF +DE SI ++ AV+ GNL+F Q+++ +QA V K
Sbjct: 325 DDQEELIATDSAIDILGFTNDEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADK 384
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L GL +L KA PR+KVG EFV K Q EQ AV A+AKA Y+++F W+V RI
Sbjct: 385 AAYLQGLNSADLLKALCYPRVKVGNEFVTKGQTVEQVTNAVGALAKAVYDKMFLWMVARI 444
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 445 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 503
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL + H K
Sbjct: 504 KEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSSN 563
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P + ++++HF+++HYAG VDY+ WL KN DPLNE VVGL Q S+ +A ++
Sbjct: 564 FQKPKVVKGKAEAHFSLIHYAGVVDYNITGWLDKNKDPLNETVVGLYQKSSVKTLALLFS 623
Query: 1870 DAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHE 2049
A+ A AE G + + F+TVS L +E L KLMT LR+T PHFVRCIIPN
Sbjct: 624 GAQTAD---AEAGGVKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 680
Query: 2050 KKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDG 2226
K G + LVL QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L IP+ FID
Sbjct: 681 KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDS 740
Query: 2227 KESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSR 2406
K++ K++ ++DID Y+ G +KVFF+ G+L LEE RD KL +I QA+CRGFL+R
Sbjct: 741 KKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQIITRTQARCRGFLAR 800
Query: 2407 RLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRA 2586
Y N A++ +++W W +LF ++KPLL+ T+ E+ +E +
Sbjct: 801 VEYQKMVERRESIFCIQYNIRAFMNVKHWPWMKLFFRIKPLLKSAETEKEMATMKEEFQK 860
Query: 2587 TKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYI 2766
TK+ L K E +E E+K+ ++ E+ +Q Q+Q E+E A+ ++ +L +LE
Sbjct: 861 TKDELAKSEAKRKELEEKMVSLLKEKNDLQLQVQSEAEGLADAEERCDQLIKTKIQLEAK 920
Query: 2767 VNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXX 2946
+ ++ +R +RK + + +K +
Sbjct: 921 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 980
Query: 2947 XXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDL 3126
+ L E++ KAK +LE Q+ +LE L
Sbjct: 981 TEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSL 1040
Query: 3127 NRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEES 3306
+E++ + +LE+ KRKL +L+ +++ + + + ++L+ +L K++ E+ + ++ ++E
Sbjct: 1041 EQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEIGNLQSKIEDEQ 1100
Query: 3307 ANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT 3486
A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L++ AT
Sbjct: 1101 ALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEI-SERLEEAGGAT 1159
Query: 3487 MLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQL 3663
Q M++K E E +R +E+ E + K + V EL +QI+ ++ + +L
Sbjct: 1160 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKL 1219
Query: 3664 EKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQL 3843
EK++++ E D+A + + ++ +++K + E + E+++ E L Q
Sbjct: 1220 EKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQVSELKSKEEEQQRLINDLTAQR 1279
Query: 3844 ERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLE 4023
R + E +R +E+E + + R + K A + +
Sbjct: 1280 GRLQTEAGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSR 1339
Query: 4024 DEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHL 4203
+ + L ++ EE + +A L++ + A + R K E Q+ EEL + + + L
Sbjct: 1340 HDCDLLREQYEEEQESKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1399
Query: 4204 QKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEER 4374
Q E E + + ++K+++Q E+ED +++E A+ +K+Q+ F+ +AE +
Sbjct: 1400 QAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWK 1459
Query: 4375 VAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKD 4554
++ + +A +E R T + + N + + LE R ++LQQE+ D
Sbjct: 1460 QKYEETHAELEASQKEARSLGTELFKMKNAYEESLDQLETLKRENKNLQQEISDLTEQIA 1519
Query: 4555 DFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAIS 4734
+ GK +HELEK K+ +E E ++++ +EE E +L+ E LR+++ +KSE DR I+
Sbjct: 1520 EGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKIA 1579
Query: 4735 NKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKE 4914
KD E ++ +R ++ + ++ L+ E R ++ A+ +KK+E + E+E QL ANR+
Sbjct: 1580 EKDEEIDQLKRNHVRVVETMQTMLDAEIRSRNDAIRIKKKMEGDLNEMEIQLNHANRMAA 1639
Query: 4915 EYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQ 5094
E + Q+ ++A + +ED+ L +R+ ++AE E+LR E +
Sbjct: 1640 EALRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1699
Query: 5095 ARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRK 5265
+RK Q K++LE I+Q A +K +K
Sbjct: 1700 SRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQLQGEMEDILQEARNAEEKAKK 1759
Query: 5266 AQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEA 5445
A + +L E+ + E K++LE++ +D + ++ E E A + Q+ LEA
Sbjct: 1760 AITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQQRLDEAEQLALKGGKKQIQKLEA 1819
Query: 5446 KVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRN 5625
+V+ LE ++ E + A + R+ E+R+ + T Q E++++ + ++L++K K ++
Sbjct: 1820 RVRELEGEVESEQKRSAEAIKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKS 1879
Query: 5626 LRRQLDEAEDEMSRERTKHRNVQREADD 5709
+RQ +EAE++ + +K R +Q E ++
Sbjct: 1880 YKRQAEEAEEQSNTNLSKFRKLQHELEE 1907
Score = 153 bits (386), Expect = 6e-35
Identities = 195/933 (20%), Positives = 388/933 (40%), Gaps = 47/933 (5%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + + + +L + + ELE+ LL E D + + AE + EE +
Sbjct: 849 KEMATMKEEFQKTKDELAKSEAKRKELEEKMVSLLKEKNDLQLQVQSEAEGLADAEERCD 908
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE N L K+ R ++ EL++D++ E
Sbjct: 909 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKDIDD-------LE 960
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E L + +++ +E A + A +Q ++ +
Sbjct: 961 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1020
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK 3753
+ + K K +QV++L +EQ KK R LE+ + + + + + I ++ + +D+
Sbjct: 1021 TLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDE 1080
Query: 3754 KRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLAT 3933
K K E + +Q+ + E ++ L QL++ EL R+ E EE A R
Sbjct: 1081 KLKKKEFEIGNLQSKI----EDEQALGIQLQKKIKELQ--ARIEELEEEIEAERASRAKA 1134
Query: 3934 AXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQG 4113
RL+ A + Q+E +++K EAE
Sbjct: 1135 EKQRSDLSRELEEISERLEEAGGATSAQIE------MNKKREAE---------------- 1172
Query: 4114 AGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELED 4284
+ RR EE+ Q LRKK+ V L +Q++ + K+++ + K +++ E++D
Sbjct: 1173 FQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDD 1232
Query: 4285 SSMELENVRASHRDSEKRQKKFESQMAEER------------VAVQKALLDRDA--MSQE 4422
+ +E V + + EK + E Q++E + + Q+ L +A S++
Sbjct: 1233 LASNVETVSKAKGNLEKMCRTLEDQVSELKSKEEEQQRLINDLTAQRGRLQTEAGEFSRQ 1292
Query: 4423 LRDRETRVLSL-------LNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHEL 4581
L ++E V L +++ +K LEE + + +L LQ S + D + E
Sbjct: 1293 LDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEE 1352
Query: 4582 EKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEK 4761
+++K L+ L ++ EV K E+D AI + E EE
Sbjct: 1353 QESKAELQRAL-------------------SKANSEVAQWRTKYETD-AIQRTE-ELEEA 1391
Query: 4762 RRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVAN----RLKEEYXXX 4929
++ L ++++ E +E + +++++N++ +L +E N L ++
Sbjct: 1392 KKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNF 1451
Query: 4930 XXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQX 5109
+Y+ E ++++ +L E + A E +QL E L + K
Sbjct: 1452 DKILAEWKQKYEETHAELEASQKEARSLGTELFKMKNAYEESLDQL----ETLKRENKNL 1507
Query: 5110 XXXXXXXXXXRAKGGGISSE---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQL 5280
A+GG E K+++E + ++ +++ E K + Q++L
Sbjct: 1508 QQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLEL 1567
Query: 5281 EQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSR--ARAQMAALEAKVQ 5454
Q+ +++ +R + +K E Q R + T L++ +SR A +E +
Sbjct: 1568 NQVKSEI--DRKIAEKDEEIDQLKRNHVRVVETMQTMLDAEIRSRNDAIRIKKKMEGDLN 1625
Query: 5455 YLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRR 5634
+E QLN + A R R + L DT +D R E KE L + L+
Sbjct: 1626 EMEIQLNHANRMAAEALRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAMVERRANLLQA 1685
Query: 5635 QLDEAEDEMSRERTKHRNVQREADDLLDANEQL 5733
+++E + + + ++E LLDA+E++
Sbjct: 1686 EIEELRATLEQTERSRKIAEQE---LLDASERV 1715
Score = 124 bits (311), Expect = 3e-26
Identities = 137/758 (18%), Positives = 312/758 (41%), Gaps = 47/758 (6%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + ++ D++ + + +R +LE++ +E+ D+ ++ AD ++
Sbjct: 848 EKEMATMKEEFQKTKDELAKSEAKRKELEEKMVSLLKEKNDLQLQVQSEAEGLADAEERC 907
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ + +E L + + DE L + ++ E A ++
Sbjct: 908 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 967
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ K A N+ + L +E L +E +K +
Sbjct: 968 KE---------------------KHATENKVKNLTEEMAGL----DETIAKLTKEKKALQ 1002
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
A Q + + E+ VN L + + K + V+ L+ LE+ + + + ++K+K++ +L
Sbjct: 1003 EAHQQTLDDLQAEEDKVNT-LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDL 1061
Query: 4279 ---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL 4449
++S M++EN + D + ++K+FE + ++ ++AL + +++++ + R+
Sbjct: 1062 KLAQESIMDIENEK-QQLDEKLKKKEFEIGNLQSKIEDEQAL--GIQLQKKIKELQARIE 1118
Query: 4450 SLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRV 4629
L E++ + ++++ R L +EL++ ++ G + + EAE MR
Sbjct: 1119 ELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR 1178
Query: 4630 QME----------------------ELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
+E EL + + + + +LE +K E D SN
Sbjct: 1179 DLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASN-- 1236
Query: 4744 VEAEEKRRGLLK--------QIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
VE K +G L+ Q+ +L+++ E ++R + + R +++ + GE +QL+
Sbjct: 1237 VETVSKAKGNLEKMCRTLEDQVSELKSKEEEQQRLINDLTAQRGRLQTEAGEFSRQLDEK 1296
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLR----EADRKFRAVEAEREQL 5067
L + E + + EE +AK +A L+ + D E E+E
Sbjct: 1297 EALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESK 1356
Query: 5068 REANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELA 5247
E L +A + + E K++L ++ + C
Sbjct: 1357 AELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASL 1416
Query: 5248 IDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES---GAQSRA 5418
+++ Q ++E + D+ + ++++ ++ ++K K E + +Q A
Sbjct: 1417 EKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKYEETHAELEASQKEA 1476
Query: 5419 RAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELL 5598
R+ L E+ L+ + R + L++ ++D T+Q + + + +++
Sbjct: 1477 RSLGTELFKMKNAYEESLD----QLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIK 1532
Query: 5599 EKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
++ + L+ L+EAE + E K +Q E + +
Sbjct: 1533 KQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQV 1570
Score = 111 bits (277), Expect = 2e-22
Identities = 177/898 (19%), Positives = 357/898 (39%), Gaps = 121/898 (13%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ +E ++ +E++ ++ ++KL + E +Q +++ E +L LQ
Sbjct: 1055 RKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEIGNLQSKIEDEQALGIQLQKKIKELQ 1114
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + +R S R ++E + + +
Sbjct: 1115 ARIEELEEEIE--AERASRAKAEKQRSDLSR--ELEEISERLEEAGGATSAQIEMNKKRE 1170
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K ++
Sbjct: 1171 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELG---EQIDNLQRVKQKLEKEKSEMK 1227
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K LE K+ LED L K + + L N L + LQ
Sbjct: 1228 MEIDDLASNVETVSKAKGNLE----KMCRTLEDQVSELKSKEEEQQRLINDLTAQRGRLQ 1283
Query: 3277 HQLTRY----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLE 3444
+ + DE+ A V+ + + + I+EL+ +E E A+N + +
Sbjct: 1284 TEAGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCD 1343
Query: 3445 KVKGDVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEE 3618
++ ++ + LQ +S+ + EV TK + IQ T E +EE K K +++++
Sbjct: 1344 LLREQYEEEQESKAELQRALSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQA 1401
Query: 3619 LHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME---- 3786
+ +E + + LEK + + E D+ ++ A+ A +DKK++ + L E
Sbjct: 1402 AEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQK 1461
Query: 3787 ---IQANLAESDEHKRTL--------------IDQLERSRDE------------------ 3861
A L S + R+L +DQLE + E
Sbjct: 1462 YEETHAELEASQKEARSLGTELFKMKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG 1521
Query: 3862 ---LDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEK 4032
+ L +++++ E + +Q L A R+++ +N+ + D K
Sbjct: 1522 GKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKIL---RIQL-ELNQVKSEIDRK 1577
Query: 4033 NALLDEKEE---------AEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN- 4182
A DE+ + E ++ L+ EI + R A ++K E +N+ +L N
Sbjct: 1578 IAEKDEEIDQLKRNHVRVVETMQTMLDAEIRS-RNDAIRIKKKMEGDLNEMEIQLNHANR 1636
Query: 4183 -----LRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSM-------ELENVRASHRD 4326
LR+ + Q L+++++ + L+ ++ ++++L E+E +RA+
Sbjct: 1637 MAAEALRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQ 1696
Query: 4327 SEKRQKKFESQM--AEERVAV----------QKALLDRDAMS---------QELRDRETR 4443
+E+ +K E ++ A ERV + K L+ D QE R+ E +
Sbjct: 1697 TERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQLQGEMEDILQEARNAEEK 1756
Query: 4444 VLSLLNEVDIMKEHLEES-------DRVRRSLQQELQDSISNKDDFG--------KNVHE 4578
+ + +M E L++ +R++++L+Q ++D D+ K + +
Sbjct: 1757 AKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQQRLDEAEQLALKGGKKQIQK 1816
Query: 4579 LEKAKRSLEAELNDMRVQMEELEDNL------------QIAEDAR--LRLEVTNQALKSE 4716
LE R LE E+ + + E L Q ED + LRL+ L+++
Sbjct: 1817 LEARVRELEGEVESEQKRSAEAIKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAK 1876
Query: 4717 SDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
++ + EAEE+ L + R L++ELE + A S K+ + E+ ++
Sbjct: 1877 V-KSYKRQAEEAEEQSNTNLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKI 1933
>gi|50797117|ref|XP_423922.1| PREDICTED: chick atrial myosin heavy
chain [Gallus gallus]
Length = 1884
Score = 1126 bits (2912), Expect = 0.0
Identities = 645/1856 (34%), Positives = 1040/1856 (55%), Gaps = 14/1856 (0%)
Frame = +1
Query: 184 VTISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPY 363
+T+ DV NPPKFD+IEDM+ LT+L+E +VL+NLK+RY S +IYTYSGLFCV +NPY
Sbjct: 15 LTVPEADVHPQNPPKFDRIEDMAMLTFLHEPAVLYNLKERYASWMIYTYSGLFCVTVNPY 74
Query: 364 KKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENT 543
K LP+Y+ +++ ++GKKR E+PPHIF+I+D AY++ML +RE+QSIL TGESGAGKT NT
Sbjct: 75 KWLPVYNAEVVAAYRGKKRTEVPPHIFSISDNAYQNMLTDRENQSILITGESGAGKTVNT 134
Query: 544 KKVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTV 723
K+VIQY A +A K K + G LE Q++QANP LEAFGN+KTV
Sbjct: 135 KRVIQYFASIAAIGDRK------------KEVANSSKGTLEDQIIQANPALEAFGNAKTV 182
Query: 724 KNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAK 903
+NDNSSRFGKFIRI+F +G ++ A+IE YLLEKSRV+ Q + ER++HIFYQIL
Sbjct: 183 RNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSN-KKP 241
Query: 904 EKSEYLL--EGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSA 1077
E E LL +Y ++ +T+ ++DD +E +T ++ ++GF +E + + ++ A
Sbjct: 242 ELLEMLLITNNPYDYSYVSQGEVTVASIDDSEELLATDSAFDVLGFTAEEKAGVYKLTGA 301
Query: 1078 VLLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQ 1257
++ GN++F Q+++ +QA K +L+GL +L K PR+KVG E+V K Q
Sbjct: 302 IMHFGNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQ 361
Query: 1258 NQEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFE 1437
+ +Q +++ A+AKA YE++F W+V RIN SL+ T + FIG+LDIAGFEIFD NSFE
Sbjct: 362 SVQQVYYSIGALAKAVYEKMFNWMVVRINNSLE-TKQPRQYFIGVLDIAGFEIFDFNSFE 420
Query: 1438 QICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALL 1617
Q+CIN+TNEKLQQ FN+ MF+LEQEEY++EGIEW+FIDFG+DLQ IDLIEKPMG++++L
Sbjct: 421 QLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLQACIDLIEKPMGIMSIL 480
Query: 1618 DEECLFPKANDKSFVEKLQKTH-NKHPKFIVP---DMRSKSHFAVVHYAGRVDYSADQWL 1785
+EEC+FPKA+D +F KL H K F P +S++HF+++HYAG VDY+ WL
Sbjct: 481 EEECMFPKASDMTFKAKLFDNHLGKSANFGKPRNVKGKSEAHFSLIHYAGTVDYNIIGWL 540
Query: 1786 MKNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQL 1965
KN DPLNE VVGL Q S +A ++ + +AG A G + + F+TVS L
Sbjct: 541 EKNKDPLNETVVGLYQKSALKLLASLF--SNYAGADAGGDGGKGKGAKKKGSSFQTVSAL 598
Query: 1966 HKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFP 2145
H+E L KLM L+ T PHFVRC+IPN K+ G +++ LV+ QLRCNGVLEGIRICR+GFP
Sbjct: 599 HRENLNKLMANLKTTHPHFVRCLIPNERKEPGVMDNPLVMHQLRCNGVLEGIRICRKGFP 658
Query: 2146 NRVPFQEFRHRYEILTPDVIPK-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVL 2322
NR+ + +FR RY IL P IP+ FID ++ K++ +LDID N Y+ G +KVFF+ G+L
Sbjct: 659 NRILYGDFRQRYRILNPTAIPEGQFIDSRKGAEKLLGSLDIDHNQYKFGHTKVFFKAGLL 718
Query: 2323 AHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWW 2502
LEE RD +L+ +I QAQ RG L R + N A++ ++NW W
Sbjct: 719 GLLEEMRDERLSLIITRIQAQARGQLMRIEFKKILERRDALLVIQWNIRAFMGVKNWPWM 778
Query: 2503 RLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQ 2682
+L+ K+KPLL+ T+ E++ +E KE L K E +E E+K+ ++ E+ +Q Q
Sbjct: 779 KLYFKIKPLLKSAETEKEMQTMKEEFGHLKEALEKSEARRKELEEKMVSMLQEKNDLQLQ 838
Query: 2683 LQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDX 2862
+Q E +N A+ ++ +L +LE V +M +RL +RK + +
Sbjct: 839 VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMTERLEEEEEMNAELAAKKRKLEDECSEL 898
Query: 2863 XXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQL 3042
+K + + L
Sbjct: 899 KKDIDDLELSLAKVEKEKHATENKVKNLTEEMAGLDENITKLTKEKKILQESHQQALDDL 958
Query: 3043 LDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKM 3222
E++ KAK +LE Q +LE L +E++ + +LE+ KRKL +L+ +++ + +
Sbjct: 959 QAEEDKVNTLAKAKVKLEQQADDLESSLEQEKKIRMDLERAKRKLEGDLKLAQESIMDLE 1018
Query: 3223 GKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARN 3402
++L +L K+D EL R ++E A +QK+++++Q I+EL E++E ER R
Sbjct: 1019 NDKQQLEERLKKKDFELNTLNARIEDEQAISAQLQKKLKELQARIEELEEELEAERTGRA 1078
Query: 3403 KAEMTRREVVAQLEKVKGDVLDKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKI 3579
K E R E++ +LE+ + L++ AT +Q +L +++ E +R +E+ E
Sbjct: 1079 KVEKLRSELLQELEET-SERLEEAGGATSVQLELNKKREAEFQKLRRDLEEATLQHEATA 1137
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKR 3759
+ K + V EL +Q++ ++ + +LEK++++ E D+ L ++ +++K
Sbjct: 1138 ATLRKKHADSVAELSEQLDNLQRVKQKLEKEKSELKLELDDVNSNTEQLIKAKTNLEKMC 1197
Query: 3760 KIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAX 3939
+ E + E ++ L E+ L Q + + E L+R EE+E + R T
Sbjct: 1198 RTTEDQMNEHRSKLEEAQRTVTDLSTQRAKLQTENSELSRQLEEKEAFINQLTRGKLTYT 1257
Query: 3940 XXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAG 4119
+ K A + + + + + L ++ EE +A L++ + A
Sbjct: 1258 QQLEDLKRQLEEEAKAKNALAHALQSAQHDCDLLREQYEEEMEAKAELQRALSKANSEVA 1317
Query: 4120 EARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSS 4290
+ R K E Q+ EEL + + + LQ+ E E + + ++K ++Q E+ED
Sbjct: 1318 QWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLM 1377
Query: 4291 MELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVD 4470
++E A+ +K+Q+ F+ ++E + +++ + +A +E R T + L N +
Sbjct: 1378 ADVERSNAAAAALDKKQRNFDKILSEWKQKFEESQTELEASQKEARSLSTELFKLKNAYE 1437
Query: 4471 IMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELED 4650
EHLE R ++LQ+E+ D K++HELEK ++ L+AE +++ +EE E
Sbjct: 1438 ESLEHLETFKRENKNLQEEILDLTEQLGASQKSIHELEKVRKQLDAEKLELQAALEEAEA 1497
Query: 4651 NLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKS 4830
+L+ E LR ++ +K++ +R ++ KD E E+ +R L+ + L+ L+ E R ++
Sbjct: 1498 SLEHEEGKILRAQLEFNQVKADYERKLAEKDEEIEQSKRNHLRVVDSLQTSLDAETRSRN 1557
Query: 4831 GAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAA 5010
A+ +KK+E + E+E QL ANR E + Q++ ++ +A ED+
Sbjct: 1558 EALRLKKKMEGDLNEMEIQLSHANRTAAEAQKQVKALQGYLKDTQLQLDDVVRANEDLKE 1617
Query: 5011 LLREADRKFRAVEAEREQLREANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRR 5181
+ +R+ +++E E+LR E +ARK Q +K++
Sbjct: 1618 NIAIVERRNNLLQSELEELRAMVEQSERARKLAEQELIEASERVQLLHSQNTSLINQKKK 1677
Query: 5182 LEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERS 5361
+EA I+Q C A +K +KA + +L E+ + E K+++E++
Sbjct: 1678 MEADISQLQTEVEEAIQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT 1737
Query: 5362 NRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLND 5541
+D + ++ E E A + Q+ LE +V+ LE++L E + + + R+ E+R+ +
Sbjct: 1738 VKDLQLRLDEAEQLALKGGKKQLQKLEVRVRELENELEAEQKRNAESIKGLRKSERRVKE 1797
Query: 5542 TTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+ Q E++++ + ++L++K LK + +RQ +EAE++ + K R VQ E D+
Sbjct: 1798 LSYQTEEDRKNMVRLQDLVDKLQLKVKAYKRQAEEAEEQANSNLAKFRKVQHELDE 1853
Score = 156 bits (394), Expect = 7e-36
Identities = 174/859 (20%), Positives = 372/859 (43%), Gaps = 52/859 (6%)
Frame = +1
Query: 3325 QKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLM 3504
+K+M+ M+ L+E +E K+E R+E+ EK+ + +K D +Q
Sbjct: 794 EKEMQTMKEEFGHLKEALE-------KSEARRKELE---EKMVSMLQEKNDLQLQVQ--- 840
Query: 3505 SRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQA 3684
+ +D +A +R + I++ K + +V+E+ +++E+ ++ ++L ++ +
Sbjct: 841 AEQDNLADAEERCDQLIKN---------KIQLEAKVKEMTERLEEEEEMNAELAAKKRKL 891
Query: 3685 DQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEH-------KRTLIDQL 3843
+ E +++ ++I L+ S A ++K++ E + + +A DE+ K+ L +
Sbjct: 892 EDECSELKKDIDDLELSLAKVEKEKHATENKVKNLTEEMAGLDENITKLTKEKKILQESH 951
Query: 3844 ERSRDELDHLNRVREEEEHAFANMQRRLAT-AXXXXXXXXXXXXXXTRLKIANINRARQL 4020
+++ D+L + E++ + A + +L A L+ A L
Sbjct: 952 QQALDDL----QAEEDKVNTLAKAKVKLEQQADDLESSLEQEKKIRMDLERAKRKLEGDL 1007
Query: 4021 EDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEH 4200
+ + +++D + + + L L+K+ AR + E++++ QL++ K+ +E
Sbjct: 1008 KLAQESIMDLENDKQQLEERLKKKDFELN--TLNARIEDEQAISAQLQKKLKELQARIEE 1065
Query: 4201 LQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVA 4380
L+++LE + ++ + + ++ QELE++S LE + + KK E++ + R
Sbjct: 1066 LEEELEAERTGRAKVEKLRSELLQELEETSERLEEAGGATSVQLELNKKREAEFQKLRRD 1125
Query: 4381 VQKALLDRDAMSQELRDRET-RVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDD 4557
+++A L +A + LR + V L ++D ++ ++ ++ + L+ EL D SN +
Sbjct: 1126 LEEATLQHEATAATLRKKHADSVAELSEQLDNLQRVKQKLEKEKSELKLELDDVNSNTEQ 1185
Query: 4558 FGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISN 4737
K LEK R+ E ++N+ R ++EE + + R +L+ N SE R +
Sbjct: 1186 LIKAKTNLEKMCRTTEDQMNEHRSKLEEAQRTVTDLSTQRAKLQTEN----SELSRQLEE 1241
Query: 4738 KDVEAEEKRRGLL---KQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRL 4908
K+ + RG L +Q+ DL+ +LE E + K+ + ++ L +Q E
Sbjct: 1242 KEAFINQLTRGKLTYTQQLEDLKRQLEEEAKAKNALAHALQSAQHDCDLLREQYEEEMEA 1301
Query: 4909 KEEYXXXXXXXXXXXXEYQIE--------CEEARQAKEDIAALLREADRKFRAVEAE--- 5055
K E +++ + EE +AK+ +A L+EA+ AV A+
Sbjct: 1302 KAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSS 1361
Query: 5056 ----REQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXX 5223
+ +L+ E LM ++ + I SE K++ E +
Sbjct: 1362 LEKTKHRLQNEIEDLMADVERSNAAAAALDKKQRNFDKILSEWKQKFEESQTELEASQKE 1421
Query: 5224 XQSNCELAIDKQRKAQVQLEQITT-------------DLSMERTLNQKT----EAEKQSL 5352
+S + + LE + T DL+ + +QK+ E ++ L
Sbjct: 1422 ARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEILDLTEQLGASQKSIHELEKVRKQL 1481
Query: 5353 ERSNRDYKAKITELESGAQSRA----RAQMAALEAKVQY----LEDQLNVEGQEKTAANR 5508
+ + +A + E E+ + RAQ+ + K Y E +E Q K R
Sbjct: 1482 DAEKLELQAALEEAEASLEHEEGKILRAQLEFNQVKADYERKLAEKDEEIE-QSKRNHLR 1540
Query: 5509 AARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRN 5688
L+ L+ T+ + R ++ + L + ++ + R EA+ ++ + ++
Sbjct: 1541 VVDSLQTSLDAETRSRNEALRLKKKMEGDLNEMEIQLSHANRTAAEAQKQVKALQGYLKD 1600
Query: 5689 VQREADDLLDANEQLTREL 5745
Q + DD++ ANE L +
Sbjct: 1601 TQLQLDDVVRANEDLKENI 1619
Score = 73.9 bits (180), Expect = 4e-11
Identities = 105/500 (21%), Positives = 204/500 (40%), Gaps = 59/500 (11%)
Frame = +1
Query: 4429 DRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVH----------- 4575
+ E + ++ E +KE LE+S+ R+ L++++ + K+D V
Sbjct: 792 ETEKEMQTMKEEFGHLKEALEKSEARRKELEEKMVSMLQEKNDLQLQVQAEQDNLADAEE 851
Query: 4576 ---ELEKAKRSLEAELNDMRVQMEELED-NLQIAEDARLRLEVTNQALKSESD------- 4722
+L K K LEA++ +M ++EE E+ N ++A R +LE LK + D
Sbjct: 852 RCDQLIKNKIQLEAKVKEMTERLEEEEEMNAELAAKKR-KLEDECSELKKDIDDLELSLA 910
Query: 4723 ------RAISNKDVEAEEKRRGLLKQIRDLENE--------------LENEKRGKSGAVS 4842
A NK E+ GL + I L E L+ E+ +
Sbjct: 911 KVEKEKHATENKVKNLTEEMAGLDENITKLTKEKKILQESHQQALDDLQAEEDKVNTLAK 970
Query: 4843 HRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLRE 5022
+ K+E Q +LE LE +++ + Q + K+ + L++
Sbjct: 971 AKVKLEQQADDLESSLEQEKKIRMDLERAKRKLEGDLKLAQESIMDLENDKQQLEERLKK 1030
Query: 5023 ADRKFRAVEAERE-------QLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRR 5181
D + + A E QL++ + L ++ RAK + SE +
Sbjct: 1031 KDFELNTLNARIEDEQAISAQLQKKLKELQARIEELEEELEAERTGRAKVEKLRSELLQE 1090
Query: 5182 LEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERS 5361
LE ++ +L ++K+R+A+ Q ++ DL E TL EA +L +
Sbjct: 1091 LEE--TSERLEEAGGATSVQLELNKKREAEFQ--KLRRDLE-EATLQH--EATAATLRKK 1143
Query: 5362 NRDYKAKITE-LESGAQSRARAQMAALEAKVQYLEDQLNVEG--QEKTAANRAARRLEKR 5532
+ D A+++E L++ + + + + E K++ + N E + KT + R E +
Sbjct: 1144 HADSVAELSEQLDNLQRVKQKLEKEKSELKLELDDVNSNTEQLIKAKTNLEKMCRTTEDQ 1203
Query: 5533 LNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAE---DEMSRERTKH----RNV 5691
+N+ + E+ +R K +N L RQL+E E ++++R + + ++
Sbjct: 1204 MNEHRSKLEEAQRTVTDLSTQRAKLQTENSELSRQLEEKEAFINQLTRGKLTYTQQLEDL 1263
Query: 5692 QREADDLLDANEQLTRELMN 5751
+R+ ++ A L L +
Sbjct: 1264 KRQLEEEAKAKNALAHALQS 1283
>gi|1842051|gb|AAB47555.1| myosin heavy chain [Gallus gallus]
Length = 1939
Score = 1125 bits (2911), Expect = 0.0
Identities = 657/1888 (34%), Positives = 1054/1888 (55%), Gaps = 14/1888 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V E F+ G+I+ + +V V+ + +T+ D V NPPK+DKIEDM+ +T+L
Sbjct: 40 FVVHPKESFVKGTIQSKEGGKVTVK-TEGGETLTVKEDQVFSMNPPKYDKIEDMAMMTHL 98
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 99 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVLAYRGKKRQEAPPHIFS 158
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A + K + +
Sbjct: 159 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAASGEKKKEEQSGKMQ-- 216
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 217 ---------GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIE 267
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPNV 981
YLLEKSRV Q ERS+HIFYQI+ E + LL + +Y ++ IT+P++
Sbjct: 268 TYLLEKSRVTFQLPAERSYHIFYQIMSN-KKPELIDMLLITTNPYDYHYVSQGEITVPSI 326
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
DD +E +T +++ I+GF+ DE ++I ++ AV+ GNL+F Q+++ +QA V K
Sbjct: 327 DDQEELMATDSAIDILGFSADEKTAIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADK 386
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L+GL EL KA PR+KVG EFV K Q Q +V A+AKA YE++F W+V RI
Sbjct: 387 AAYLMGLNSAELLKALCYPRVKVGNEFVTKGQTVSQVHNSVGALAKAVYEKMFLWMVIRI 446
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 447 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H K
Sbjct: 506 KEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNN 565
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P ++++HF++VHYAG VDY+ WL KN DPLNE V+GL Q S+ +A ++
Sbjct: 566 FQKPKPAKGKAEAHFSLVHYAGTVDYNISGWLEKNKDPLNETVIGLYQKSSVKTLALLF- 624
Query: 1870 DAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHE 2049
A + G AE G + + F+TVS L +E L KLM LR+T PHFVRCIIPN
Sbjct: 625 -ATYGG--EAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMANLRSTHPHFVRCIIPNET 681
Query: 2050 KKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDG 2226
K G + LVL QLRCNGVLEGIRICR+GFP+RV + +F+ RY +L IP+ F+D
Sbjct: 682 KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRVLYADFKQRYRVLNASAIPEGQFMDS 741
Query: 2227 KESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSR 2406
K++ K++ ++D+D YR G +KVFF+ G+L LEE RD KL +I QA+CRGFL R
Sbjct: 742 KKASEKLLGSIDVDHTQYRFGHTKVFFKAGLLGLLEEMRDDKLAEIITRTQARCRGFLMR 801
Query: 2407 RLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRA 2586
Y N +++ +++W W +LF K+KPLL+ ++ E+ +E
Sbjct: 802 VEYRRMVERRESIFCIQYNVRSFMNVKHWPWMKLFFKIKPLLKSAESEKEMANMKEEFEK 861
Query: 2587 TKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYI 2766
TKE L K E +E E+K+ ++ E+ +Q Q+Q E+++ A+ ++ +L +LE
Sbjct: 862 TKEELAKSEAKRKELEEKMVVLLQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAK 921
Query: 2767 VNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXX 2946
+ ++ +R +RK + + +K +
Sbjct: 922 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNF 981
Query: 2947 XXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDL 3126
+ L E++ KAK +LE Q+ +LE L
Sbjct: 982 TEEMAVLDETIAKLTKEKKALQEAHQQTLDDLQVEEDKVNTLTKAKTKLEQQVDDLEGSL 1041
Query: 3127 NRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEES 3306
+E++ + +LE+ KRKL +L+ + D + + ++L+ +L K+D E+ ++ ++E
Sbjct: 1042 EQEKKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQ 1101
Query: 3307 ANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT 3486
A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L++ AT
Sbjct: 1102 ALGMQLQKKIKELQARIEELEEEIEAERTSRAKAEKHRADLSRELEEI-SERLEEAGGAT 1160
Query: 3487 MLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQL 3663
Q M++K E E +R +E+ E + K + EL +QI+ ++ + +L
Sbjct: 1161 AAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKL 1220
Query: 3664 EKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQL 3843
EK++++ E D+A + + ++A+++K + E L EI+ ++ L Q
Sbjct: 1221 EKEKSELKMEIDDLASNMESVSKAKANLEKMCRTLEDQLSEIKTKEEQNQRMINDLNTQR 1280
Query: 3844 ERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLE 4023
R + E +R EE++ + + R + K A + +
Sbjct: 1281 ARLQTETGEYSRQAEEKDALISQLSRGKQGFTQQIEELKRHLEEEIKAKNALAHALQSAR 1340
Query: 4024 DEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHL 4203
+ L ++ EE + + L++ + A + R K E Q+ EEL + + + L
Sbjct: 1341 HDCELLREQYEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1400
Query: 4204 QKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEER 4374
Q E E + + ++K+++Q E+ED +++E A+ +K+QK F+ +AE +
Sbjct: 1401 QDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMVDVERSNAACAALDKKQKNFDKILAEWK 1460
Query: 4375 VAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKD 4554
++ + +A +E R T + + N + +HLE R ++LQQE+ D
Sbjct: 1461 QKYEETQTELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEIADLTEQIA 1520
Query: 4555 DFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAIS 4734
+ GK VHELEK K+ +E E ++++ +EE E +L+ E LRL++ +KSE DR I+
Sbjct: 1521 EGGKAVHELEKVKKHVEQEKSELQASLEEAEASLEHEEGKILRLQLELNQIKSEIDRKIA 1580
Query: 4735 NKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKE 4914
KD E ++ +R L+ + +++ L+ E R ++ A+ +KK+E + E+E QL ANR+
Sbjct: 1581 EKDEEIDQLKRNHLRIVESMQSTLDAEIRSRNEALRLKKKMEGDLNEMEIQLSHANRMAA 1640
Query: 4915 EYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQ 5094
E + QI ++A + +ED+ + +R+ ++AE E+LR A E +
Sbjct: 1641 EAQKNLRNTQGTLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEVEELRGALEQTER 1700
Query: 5095 ARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRK 5265
+RK Q K++LE I Q A +K +K
Sbjct: 1701 SRKVAEQELLDATERVQLLHTQNTSLINTKKKLETDIVQIQSEMEDTIQEARNAEEKAKK 1760
Query: 5266 AQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEA 5445
A + +L E+ + E K++++++ +D ++ E E A + Q+ LEA
Sbjct: 1761 AITDAAMMAEELKKEQDTSAHLERMKKNMDQTVKDLHVRLDEAEQLALKGGKKQLQKLEA 1820
Query: 5446 KVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRN 5625
+V+ LE +++ E + A + R+ E+R+ + T Q E++++ + ++L++K +K ++
Sbjct: 1821 RVRELEGEVDSEQKRSAEAVKGVRKYERRVKELTYQCEEDRKNILRLQDLVDKLQMKVKS 1880
Query: 5626 LRRQLDEAEDEMSRERTKHRNVQREADD 5709
+RQ +EAE+ + +K R +Q E ++
Sbjct: 1881 YKRQAEEAEELSNVNLSKFRKIQHELEE 1908
Score = 164 bits (415), Expect = 2e-38
Identities = 189/922 (20%), Positives = 383/922 (41%), Gaps = 36/922 (3%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + + +++L + + ELE+ LL E D + + A+ + EE +
Sbjct: 850 KEMANMKEEFEKTKEELAKSEAKRKELEEKMVVLLQEKNDLQLQVQAEADSLADAEERCD 909
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE N L K+ R ++ EL++D++ E
Sbjct: 910 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKDIDD-------LE 961
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQ------IQHTMEG 3573
+T +V + + V + +E +L + +++ +E A + A +Q ++
Sbjct: 962 LTLAKVEKEKHATENKVKNFTEEMAVLDETIAKLTKEKKALQEAHQQTLDDLQVEEDKVN 1021
Query: 3574 KIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK 3753
+ + K K +QV++L +EQ KK R LE+ + + + + I L+ + +D+
Sbjct: 1022 TLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDE 1081
Query: 3754 KRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLAT 3933
K K + + +IQ+ + E ++ L QL++ EL R+ E EE A R
Sbjct: 1082 KLKKKDFEISQIQSKI----EDEQALGMQLQKKIKELQ--ARIEELEEEIEAERTSRAKA 1135
Query: 3934 AXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQG 4113
RL+ A A Q+E +++K EAE
Sbjct: 1136 EKHRADLSRELEEISERLEEAGGATAAQIE------MNKKREAE---------------- 1173
Query: 4114 AGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELED 4284
+ RR EE+ Q LRKK+ L +Q++ + K+++ + K +++ E++D
Sbjct: 1174 FQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDD 1233
Query: 4285 SSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNE 4464
+ +E+V + + EK + E Q++E + + + + D T+ L E
Sbjct: 1234 LASNMESVSKAKANLEKMCRTLEDQLSEIKT-------KEEQNQRMINDLNTQRARLQTE 1286
Query: 4465 VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEEL 4644
EE D + L + Q ++ +++ E KAK +L L R E L
Sbjct: 1287 TGEYSRQAEEKDALISQLSRGKQGFTQQIEELKRHLEEEIKAKNALAHALQSARHDCELL 1346
Query: 4645 EDNLQIAEDARLRL---------EVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLE 4797
+ + ++A+ L EV K E+D AI + E EE ++ L ++++D E
Sbjct: 1347 REQYEEEQEAKGELQRALSKANSEVAQWRTKYETD-AIQRTE-ELEEAKKKLAQRLQDAE 1404
Query: 4798 NELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECE 4977
+E + +++++N++ +L +E +N E++ + E
Sbjct: 1405 EHVEAVNAKCASLEKTKQRLQNEVEDLMVDVERSNAACAALDKKQKNFDKILAEWKQKYE 1464
Query: 4978 EARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGG 5157
E + E R + ++ E+ + E L + K A+GG
Sbjct: 1465 ETQTELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEIADLTEQIAEGGK 1524
Query: 5158 ISSE---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQK 5328
E K+ +E + ++ +++ E K + Q++L QI ++ +++K
Sbjct: 1525 AVHELEKVKKHVEQEKSELQASLEEAEASLEHEEGKILRLQLELNQIKSE------IDRK 1578
Query: 5329 TEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANR 5508
+ + +++ R++ + ++S + R++ AL K + +E LN + + ANR
Sbjct: 1579 IAEKDEEIDQLKRNHLRIVESMQSTLDAEIRSRNEALRLK-KKMEGDLNEMEIQLSHANR 1637
Query: 5509 AARRLEKR-------LNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSR 5667
A +K L DT +D R E KE + + L+ +++E + +
Sbjct: 1638 MAAEAQKNLRNTQGTLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEVEELRGALEQ 1697
Query: 5668 ERTKHRNVQREADDLLDANEQL 5733
+ ++E LLDA E++
Sbjct: 1698 TERSRKVAEQE---LLDATERV 1716
Score = 135 bits (341), Expect = 9e-30
Identities = 177/905 (19%), Positives = 364/905 (39%), Gaps = 136/905 (15%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ + ++ +E+D ++ ++KL + E + IQ +++ E +L LQ
Sbjct: 1056 RKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQ 1115
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + +R S R ++E + + +
Sbjct: 1116 ARIEELEEEIE--AERTSRAKAEKHRADLSR--ELEEISERLEEAGGATAAQIEMNKKRE 1171
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K L+
Sbjct: 1172 AEFQKMRRDLEEATLQHEATAAALRKKHADSTAELG---EQIDNLQRVKQKLEKEKSELK 1228
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K+ LE+ R L +L + K + + +LN Q + E
Sbjct: 1229 MEIDDLASNMESVSKAKANLEKMCRTLEDQLSEIKTKEEQNQRMINDLNTQRARLQTETG 1288
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ +E+ A ++ + + + I+EL+ +E E A+N + E ++
Sbjct: 1289 EYSRQAEEKDALISQLSRGKQGFTQQIEELKRHLEEEIKAKNALAHALQSARHDCELLRE 1348
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
++ + LQ +S+ + EV TK + IQ T E +EE K K ++++++ +
Sbjct: 1349 QYEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQDAEEH 1406
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME-------I 3789
+E + + LEK + + E D+ ++ A+ A +DKK+K + L E
Sbjct: 1407 VEAVNAKCASLEKTKQRLQNEVEDLMVDVERSNAACAALDKKQKNFDKILAEWKQKYEET 1466
Query: 3790 QANLAESDEHKRTLIDQLERSR----DELDHLNRVREEEEHAFANMQRRLATAXXXXXXX 3957
Q L S + R+L +L + + + LDHL ++ E + N+Q+ +A
Sbjct: 1467 QTELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENK----NLQQEIADLTEQIAEG 1522
Query: 3958 XXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKA 4137
++K + +E EK+ L EEAE H E +I + + + +
Sbjct: 1523 GKAVHELEKVK-------KHVEQEKSELQASLEEAEASLEHEEGKILRLQLELNQIKSEI 1575
Query: 4138 EESV---NQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE-- 4302
+ + ++++++L++ +LR VE +Q L+ ++ L+ KKK++ +L + ++L
Sbjct: 1576 DRKIAEKDEEIDQLKRNHLRIVESMQSTLDAEIRSRNEALRLKKKMEGDLNEMEIQLSHA 1635
Query: 4303 ------------NVRASHRDS---------------------EKRQKKFESQMAEERVAV 4383
N + + +D+ E+R ++++ E R A+
Sbjct: 1636 NRMAAEAQKNLRNTQGTLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEVEELRGAL 1695
Query: 4384 QKALLDRDAMSQELRDRETRV-------LSLLN-----EVDIMKEHLEESDRVR--RSLQ 4521
++ R QEL D RV SL+N E DI++ E D ++ R+ +
Sbjct: 1696 EQTERSRKVAEQELLDATERVQLLHTQNTSLINTKKKLETDIVQIQSEMEDTIQEARNAE 1755
Query: 4522 QELQDSISN--------KDDFGKNVHELEKAKRSLEAELNDMRVQMEELED-NLQIAEDA 4674
++ + +I++ K + + H LE+ K++++ + D+ V+++E E L+ +
Sbjct: 1756 EKAKKAITDAAMMAEELKKEQDTSAH-LERMKKNMDQTVKDLHVRLDEAEQLALKGGKKQ 1814
Query: 4675 RLRLEVTNQALKSESD-----------------RAISNKDVEAEEKRRGLLK-------- 4779
+LE + L+ E D R + + EE R+ +L+
Sbjct: 1815 LQKLEARVRELEGEVDSEQKRSAEAVKGVRKYERRVKELTYQCEEDRKNILRLQDLVDKL 1874
Query: 4780 -----------------------QIRDLENELE-------------NEKRGKSGAVSHRK 4851
+ R +++ELE N+ R KS + H K
Sbjct: 1875 QMKVKSYKRQAEEAEELSNVNLSKFRKIQHELEEAEERADIAESQVNKLRVKSREI-HGK 1933
Query: 4852 KIENQ 4866
KIE +
Sbjct: 1934 KIEEE 1938
Score = 125 bits (315), Expect = 9e-27
Identities = 146/760 (19%), Positives = 313/760 (40%), Gaps = 49/760 (6%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + E+ +++ + + +R +LE++ QE+ D+ ++ S AD ++
Sbjct: 849 EKEMANMKEEFEKTKEELAKSEAKRKELEEKMVVLLQEKNDLQLQVQAEADSLADAEERC 908
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ + +E L + + DE L + ++ E A ++
Sbjct: 909 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 968
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ T K+ N + DE A L ++++A +
Sbjct: 969 KE---------------KHATENKVKNFTEEMAVLDETIAKLTKEKKA----------LQ 1003
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
A Q + + E+ VN L + + K + V+ L+ LE+ + + + ++K+K++ +L
Sbjct: 1004 EAHQQTLDDLQVEEDKVNT-LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDL 1062
Query: 4279 E---DSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL 4449
+ DS M+LEN + D + ++K FE + ++ ++AL + +++++ + R+
Sbjct: 1063 KLAHDSIMDLENDK-QQLDEKLKKKDFEISQIQSKIEDEQAL--GMQLQKKIKELQARIE 1119
Query: 4450 SLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFG-----------KNVHELEKAKR 4596
L E++ + ++++ R L +EL++ ++ G K E +K +R
Sbjct: 1120 ELEEEIEAERTSRAKAEKHRADLSRELEEISERLEEAGGATAAQIEMNKKREAEFQKMRR 1179
Query: 4597 SL-EAELN-------------DMRVQMEELEDNLQIA------EDARLRLEVTNQALKSE 4716
L EA L D ++ E DNLQ E + L++E+ + A E
Sbjct: 1180 DLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNME 1239
Query: 4717 SDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEV 4896
S +S E+ R L Q+ +++ + E +R + + R +++ + GE +Q E
Sbjct: 1240 S---VSKAKANLEKMCRTLEDQLSEIKTKEEQNQRMINDLNTQRARLQTETGEYSRQAEE 1296
Query: 4897 ANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAV----EAEREQ 5064
+ L + E + EE +AK +A L+ A + E E+E
Sbjct: 1297 KDALISQLSRGKQGFTQQIEELKRHLEEEIKAKNALAHALQSARHDCELLREQYEEEQEA 1356
Query: 5065 LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCEL 5244
E L +A + + E K++L ++ + C
Sbjct: 1357 KGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCAS 1416
Query: 5245 AIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKI----TELESGAQS 5412
+++ Q ++E + D+ + ++++ ++ ++K K TELE+ +
Sbjct: 1417 LEKTKQRLQNEVEDLMVDVERSNAACAALDKKQKNFDKILAEWKQKYEETQTELEASQKE 1476
Query: 5413 RARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKE 5592
+ K Y E ++E R + L++ + D T+Q + +A + ++
Sbjct: 1477 SRSLSTELFKMKNAYEESLDHLE-----TLKRENKNLQQEIADLTEQIAEGGKAVHELEK 1531
Query: 5593 LLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ + + L+ L+EAE + E K +Q E + +
Sbjct: 1532 VKKHVEQEKSELQASLEEAEASLEHEEGKILRLQLELNQI 1571
Score = 68.9 bits (167), Expect = 1e-09
Identities = 103/519 (19%), Positives = 195/519 (36%), Gaps = 16/519 (3%)
Frame = +1
Query: 4234 KERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAM 4413
K + L + ++E+ + E E + SE ++K+ E +M L A
Sbjct: 838 KIKPLLKSAESEKEMANMKEEFEKTKEELAKSEAKRKELEEKMVVLLQEKNDLQLQVQAE 897
Query: 4414 SQELRDRETRVLSLLN-------EVDIMKEHLEESDRVRRSL---QQELQDSISNKDDFG 4563
+ L D E R L+ ++ + E E+ + + L +++L+D S +
Sbjct: 898 ADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECS---ELK 954
Query: 4564 KNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
K++ +LE +E E + +++ + + + ++ +L +AL+ + + +
Sbjct: 955 KDIDDLELTLAKVEKEKHATENKVKNFTEEMAVLDETIAKLTKEKKALQEAHQQTLDDLQ 1014
Query: 4744 VEAEE------KRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANR 4905
VE ++ + L +Q+ DLE LE EK+ R +E +LE L++A+
Sbjct: 1015 VEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKK-------LRMDLERAKRKLEGDLKLAHD 1067
Query: 4906 LKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEG 5085
+ + E + + ED AL + +K + ++A E+L E E
Sbjct: 1068 SIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQARIEELEEEIEA 1127
Query: 5086 LMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRK 5265
RAK ++ R LE +
Sbjct: 1128 --------------ERTSRAKAEKHRADLSRELE-------------------------E 1148
Query: 5266 AQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEA 5445
+LE+ + + +N+K EAE Q + R +LE A + A AAL
Sbjct: 1149 ISERLEEAGGATAAQIEMNKKREAEFQKMRR----------DLEE-ATLQHEATAAALRK 1197
Query: 5446 KVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRN 5625
K D G++ R ++LEK ++ + +D +E + N
Sbjct: 1198 K---HADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDD-------LASNMESVSKAKAN 1247
Query: 5626 LRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
L + ED++S +TK QR +DL +L E
Sbjct: 1248 LEKMCRTLEDQLSEIKTKEEQNQRMINDLNTQRARLQTE 1286
Score = 56.2 bits (134), Expect = 9e-06
Identities = 78/349 (22%), Positives = 135/349 (38%), Gaps = 51/349 (14%)
Frame = +1
Query: 4852 KIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADR 5031
KI+ + E + E+AN +KEE+ + ++ +E + LL+E +
Sbjct: 838 KIKPLLKSAESEKEMAN-MKEEFEKTKEELAKSEAK-------RKELEEKMVVLLQEKND 889
Query: 5032 KFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXX 5211
V+AE + L +A E Q K K +LEAKI +
Sbjct: 890 LQLQVQAEADSLADAEERCDQLIKT----------------------KIQLEAKIKEVTE 927
Query: 5212 XXXXXQS-NCELAIDKQRKAQVQLEQITTDLS-MERTLNQKTEAEKQSLERSNRDYKAKI 5385
+ N EL K+RK + + ++ D+ +E TL K E EK + E +++ ++
Sbjct: 928 RAEDEEEINAELTA-KKRKLEDECSELKKDIDDLELTL-AKVEKEKHATENKVKNFTEEM 985
Query: 5386 TELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDE 5565
L+ + + A EA Q L+D L VE + +A +LE++++D E E
Sbjct: 986 AVLDETIAKLTKEKKALQEAHQQTLDD-LQVEEDKVNTLTKAKTKLEQQVDDLEGSLEQE 1044
Query: 5566 KRAN---EQAKELLE----------------KSNL------------------------- 5613
K+ E+AK LE K L
Sbjct: 1045 KKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALG 1104
Query: 5614 -----KNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
K + L+ +++E E+E+ ERT ++ DL E+++ L
Sbjct: 1105 MQLQKKIKELQARIEELEEEIEAERTSRAKAEKHRADLSRELEEISERL 1153
>gi|5360750|dbj|BAA82146.1| myosin heavy chain 2x [Sus scrofa]
Length = 1939
Score = 1125 bits (2911), Expect = 0.0
Identities = 657/1888 (34%), Positives = 1056/1888 (55%), Gaps = 14/1888 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V + E F+ G+++ +V V+ + +T+ D V NPPKFDKIEDM+ +T+L
Sbjct: 39 FVAEPKESFVKGTVQSREGGKVTVK-TEAGATLTVKEDQVFPMNPPKFDKIEDMAMMTHL 97
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 98 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFS 157
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A K
Sbjct: 158 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKK---------- 207
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
++P G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 208 EEPTSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIE 267
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPNV 981
YLLEKSRV Q + ERS+HIFYQI+ E E LL + +Y F+ IT+P++
Sbjct: 268 TYLLEKSRVTFQLKAERSYHIFYQIMSN-KKPELIEMLLITTNPYDYAFVSQGEITVPSI 326
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
DD +E +T +++ I+GF DE SI ++ AV+ GNL+F Q+++ +QA V K
Sbjct: 327 DDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADK 386
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L GL +L KA PR+KVG EFV K Q +Q AV A+AKA Y+++F W+VTRI
Sbjct: 387 AAYLQGLNSADLLKALCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTRI 446
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 447 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL + H K
Sbjct: 506 KEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNN 565
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P + ++HF+++HYAG VDY+ WL KN DPLNE VVGL Q S+ +A ++
Sbjct: 566 FQKPKPAKGKVEAHFSLIHYAGTVDYNITGWLDKNKDPLNETVVGLYQKSSVKTLAFLFT 625
Query: 1870 DAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHE 2049
A A AE G + + F+TVS L +E L KLMT LR+T PHFVRCIIPN
Sbjct: 626 GAAGAD---AEAGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 682
Query: 2050 KKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDG 2226
K G + LVL QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L IP+ FID
Sbjct: 683 KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDS 742
Query: 2227 KESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSR 2406
K++ K++ ++DID Y+ G +KVFF+ G+L LEE RD KL LI QA+CRGFL+R
Sbjct: 743 KKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQARCRGFLAR 802
Query: 2407 RLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRA 2586
Y N A++ +++W W +L+ K+KPLL+ T+ E+ +E
Sbjct: 803 VEYQKMVERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFEK 862
Query: 2587 TKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYI 2766
TKE L K E +E E+K+ ++ E+ +Q Q+Q E+++ A+ ++ +L +LE
Sbjct: 863 TKESLAKAEAKRKELEEKMVALMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAK 922
Query: 2767 VNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXX 2946
+ ++ +R +RK + + +K +
Sbjct: 923 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 982
Query: 2947 XXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDL 3126
+ L E++ KAK +LE Q+ +LE L
Sbjct: 983 TEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSL 1042
Query: 3127 NRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEES 3306
+E++ + +LE+ KRKL +L+ +++ + ++L+ +L K++ E+ + ++ ++E
Sbjct: 1043 EQEKKLRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDEQ 1102
Query: 3307 ANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT 3486
A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L++ AT
Sbjct: 1103 ALAMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEI-SERLEEAGGAT 1161
Query: 3487 MLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQL 3663
Q M++K E E +R +E+ E + K + V EL +QI+ ++ + +L
Sbjct: 1162 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1221
Query: 3664 EKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQL 3843
EK++++ E D+A + + ++ +++K + E L E++ E L Q
Sbjct: 1222 EKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRTLEDQLSELKTKEEEQQRLINDLTAQR 1281
Query: 3844 ERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLE 4023
R + E +R +E++ + + R + K A + +
Sbjct: 1282 ARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHAVQSSR 1341
Query: 4024 DEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHL 4203
+ + L ++ EE + +A L++ + A + R K E Q+ EEL + + + L
Sbjct: 1342 HDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1401
Query: 4204 QKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEER 4374
Q E E + + ++K+++Q E+ED +++E A+ +K+Q+ F+ +AE +
Sbjct: 1402 QDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERSNAACAALDKKQRNFDKILAEWK 1461
Query: 4375 VAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKD 4554
++ + +A +E R T + + N + + LE R ++LQQE+ D
Sbjct: 1462 QKYEETHAELEASQKESRSLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIA 1521
Query: 4555 DFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAIS 4734
+ GK +HELEK K+ +E E ++++ +EE E +L+ E LR+++ +KSE DR I+
Sbjct: 1522 EGGKRIHELEKIKKQVEQEKSEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIA 1581
Query: 4735 NKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKE 4914
KD E ++ +R ++ + +++ L+ E R ++ A+ +KK+E + E+E QL ANR+
Sbjct: 1582 EKDEEIDQLKRNHVRVVESMQSMLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAA 1641
Query: 4915 EYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQ 5094
E + QI ++A +++ED+ L +R+ ++AE E+LR E +
Sbjct: 1642 EALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1701
Query: 5095 ARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRK 5265
+RK Q K++LE I+Q A +K +K
Sbjct: 1702 SRKVAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKK 1761
Query: 5266 AQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEA 5445
A + +L E+ + E K++LE++ +D + ++ E E A + Q+ LEA
Sbjct: 1762 AITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEA 1821
Query: 5446 KVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRN 5625
+V+ LE ++ E + + R+ E+R+ + T Q E++++ + ++L++K K ++
Sbjct: 1822 RVRELEGEVESEQKRNVETVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKS 1881
Query: 5626 LRRQLDEAEDEMSRERTKHRNVQREADD 5709
+RQ +EAE++ + +K R +Q E ++
Sbjct: 1882 YKRQAEEAEEQSNVNLSKFRKLQHELEE 1909
Score = 156 bits (395), Expect = 5e-36
Identities = 185/922 (20%), Positives = 384/922 (41%), Gaps = 36/922 (3%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + + ++ L + + ELE+ L+ E D + + A+ + EE +
Sbjct: 851 KEMANMKEEFEKTKESLAKAEAKRKELEEKMVALMQEKNDLQLQVQAEADSLADAEERCD 910
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE N L K+ R ++ EL++D++ E
Sbjct: 911 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKDIDD-------LE 962
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E L + +++ +E A + A +Q ++ +
Sbjct: 963 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1022
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIAL-LQASRADID 3750
+ + K K +QV++L +EQ KK R LE+ + + + + +AQE + ++ + +D
Sbjct: 1023 TLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGD-LKLAQESTMDIENDKQQLD 1081
Query: 3751 KKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLA 3930
+K K E + +Q+ + E ++ L QL++ EL R+ E EE A R
Sbjct: 1082 EKLKKKEFEMSNLQSKI----EDEQALAMQLQKKIKELQ--ARIEELEEEIEAERASRAK 1135
Query: 3931 TAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQ 4110
RL+ A + Q+E +++K EAE
Sbjct: 1136 AEKQRSDLSRELEEISERLEEAGGATSAQIE------MNKKREAE--------------- 1174
Query: 4111 GAGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELE 4281
+ RR EE+ Q LRKK+ V L +Q++ + K+++ + K +++ E++
Sbjct: 1175 -FQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID 1233
Query: 4282 DSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLN 4461
D + +E V + + EK + E Q++E + + + + D + L
Sbjct: 1234 DLASNMETVSKAKGNLEKMCRTLEDQLSELKT-------KEEEQQRLINDLTAQRARLQT 1286
Query: 4462 EVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE 4641
E L+E D + L + Q ++ + + E KAK +L + R +
Sbjct: 1287 ESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHAVQSSRHDCDL 1346
Query: 4642 LEDNLQIAEDARLRL---------EVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDL 4794
L + + ++A+ L EV K E+D AI + E EE ++ L ++++D
Sbjct: 1347 LREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETD-AIQRTE-ELEEAKKKLAQRLQDA 1404
Query: 4795 ENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIEC 4974
E +E + +++++N++ +L +E +N E++ +
Sbjct: 1405 EEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERSNAACAALDKKQRNFDKILAEWKQKY 1464
Query: 4975 EEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGG 5154
EE E R + V+ E+ + E L + K A+GG
Sbjct: 1465 EETHAELEASQKESRSLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGG 1524
Query: 5155 GISSE---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQ 5325
E K+++E + ++ +++ E K + Q++L Q+ ++ +++
Sbjct: 1525 KRIHELEKIKKQVEQEKSEIQAALEEAEASLEHEEGKILRIQLELNQVKSE------VDR 1578
Query: 5326 KTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAA------LEAKVQYLEDQLNVEGQ 5487
K + + +++ R++ + ++S + R++ A +E + +E QLN +
Sbjct: 1579 KIAEKDEEIDQLKRNHVRVVESMQSMLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANR 1638
Query: 5488 EKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSR 5667
A R R + L DT +D R+ E KE L + L+ +++E + +
Sbjct: 1639 MAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQ 1698
Query: 5668 ERTKHRNVQREADDLLDANEQL 5733
+ ++E LLDA+E++
Sbjct: 1699 TERSRKVAEQE---LLDASERV 1717
Score = 137 bits (345), Expect = 3e-30
Identities = 169/877 (19%), Positives = 362/877 (41%), Gaps = 85/877 (9%)
Frame = +1
Query: 3364 LREDMETERNARNKAEMTRREV---VAQLEKVKGDVLDKVD-EATMLQDLMSRKDEEVNA 3531
++E+ E + + KAE R+E+ + L + K D+ +V EA L D R D+ +
Sbjct: 856 MKEEFEKTKESLAKAEAKRKELEEKMVALMQEKNDLQLQVQAEADSLADAEERCDQLIKT 915
Query: 3532 TKRAIEQIQHTMEGKIEEQ---------KAKFSRQVEELHDQIEQHKKQRSQLEKQQNQA 3684
+ +I+ E +E+ K K + EL I+ + +++EK+++
Sbjct: 916 KIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHAT 975
Query: 3685 DQERADMAQEIALLQASRADIDKKRK-IHEAHLMEIQANLAESDEHKRTLIDQLERSRDE 3861
+ + ++ +E+A L + A + K++K + EAH + AE D+ TL + +
Sbjct: 976 ENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK-VNTLTKAKTKLEQQ 1034
Query: 3862 LDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNAL 4041
+D L E+E+ +++R LK+A +E++K L
Sbjct: 1035 VDDLEGSLEQEKKLRMDLERAKRKLEGD-------------LKLAQ-ESTMDIENDKQQL 1080
Query: 4042 LDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEE 4221
++ ++ E ++L+ +I + E+++ QL++ K+ +E L++++E
Sbjct: 1081 DEKLKKKEFEMSNLQSKI------------EDEQALAMQLQKKIKELQARIEELEEEIEA 1128
Query: 4222 SEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLD 4401
++ + + + + +ELE+ S LE + + KK E++ + R +++A L
Sbjct: 1129 ERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQ 1188
Query: 4402 RDAMSQELRDRETRVLSLLNE-VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHE 4578
+A + LR + ++ L E +D ++ ++ ++ + ++ E+ D SN + K
Sbjct: 1189 HEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGN 1248
Query: 4579 LEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEE 4758
LEK R+LE +L++++ + EE + + R RL+ + E R + KD +
Sbjct: 1249 LEKMCRTLEDQLSELKTKEEEQQRLINDLTAQRARLQTES----GEYSRQLDEKDTLVSQ 1304
Query: 4759 KRRG---LLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXX 4929
RG +QI +L+ +LE E + KS + + L +Q E K E
Sbjct: 1305 LSRGKQAFTQQIEELKRQLEEEIKAKSALAHAVQSSRHDCDLLREQYEEEQEAKAELQRA 1364
Query: 4930 XXXXXXXXXEYQIE--------CEEARQAKEDIAALLREADRKFRAVEAE-------REQ 5064
+++ + EE +AK+ +A L++A+ AV A+ +++
Sbjct: 1365 MSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQR 1424
Query: 5065 LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCEL 5244
L+ E LM ++ + I +E K++ E A+ +S
Sbjct: 1425 LQNEVEDLMIDVERSNAACAALDKKQRNFDKILAEWKQKYEETHAELEASQKESRSLSTE 1484
Query: 5245 AIDKQRKAQVQLEQITTDLSMERTLNQKT-----------------EAEKQSLERSNRDY 5373
+ + L+Q+ T + L Q+ E K+ +E+ +
Sbjct: 1485 LFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSEI 1544
Query: 5374 KAKITELESGAQSRA----RAQMAALEAK------------------------VQYLEDQ 5469
+A + E E+ + R Q+ + K V+ ++
Sbjct: 1545 QAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHVRVVESMQSM 1604
Query: 5470 LNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQA-------KELLEKSNLKNRNL 5628
L+ E + + A R +++E LN+ Q R +A + +L+ + + +
Sbjct: 1605 LDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDA 1664
Query: 5629 RRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTR 5739
R ++ +++++ + +Q E ++L EQ R
Sbjct: 1665 LRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1701
Score = 125 bits (315), Expect = 9e-27
Identities = 129/753 (17%), Positives = 315/753 (41%), Gaps = 42/753 (5%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + E+ + + + + +R +LE++ QE+ D+ ++ S AD ++
Sbjct: 850 EKEMANMKEEFEKTKESLAKAEAKRKELEEKMVALMQEKNDLQLQVQAEADSLADAEERC 909
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ + +E L + + DE L + ++ E A ++
Sbjct: 910 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 969
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ K A N+ + L +E L +E +K +
Sbjct: 970 KE---------------------KHATENKVKNLTEEMAGL----DETIAKLTKEKKALQ 1004
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
A Q + + E+ VN L + + K + V+ L+ LE+ + + + ++K+K++ +L
Sbjct: 1005 EAHQQTLDDLQAEEDKVNT-LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDL 1063
Query: 4279 ---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL 4449
++S+M++EN + D + ++K+FE + ++ ++AL + + +++++ + R+
Sbjct: 1064 KLAQESTMDIENDK-QQLDEKLKKKEFEMSNLQSKIEDEQALAMQ--LQKKIKELQARIE 1120
Query: 4450 SLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRV 4629
L E++ + ++++ R L +EL++ ++ G + + EAE MR
Sbjct: 1121 ELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR 1180
Query: 4630 QME----------------------ELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
+E EL + + + + +LE +K E D SN +
Sbjct: 1181 DLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNME 1240
Query: 4744 VEAEEKR------RGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANR 4905
++ K R L Q+ +L+ + E ++R + + R +++ + GE +QL+ +
Sbjct: 1241 TVSKAKGNLEKMCRTLEDQLSELKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDT 1300
Query: 4906 LKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLR----EADRKFRAVEAEREQLRE 5073
L + E + + EE +AK +A ++ + D E E+E E
Sbjct: 1301 LVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHAVQSSRHDCDLLREQYEEEQEAKAE 1360
Query: 5074 ANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAID 5253
+ +A + + E K++L ++ + C
Sbjct: 1361 LQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEK 1420
Query: 5254 KQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMA 5433
+++ Q ++E + D+ + ++++ ++ ++K K E + ++ ++ +
Sbjct: 1421 TKQRLQNEVEDLMIDVERSNAACAALDKKQRNFDKILAEWKQKYEETHAELEA-SQKESR 1479
Query: 5434 ALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNL 5613
+L ++ +++ + R + L++ ++D T+Q + + + +++ ++
Sbjct: 1480 SLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQ 1539
Query: 5614 KNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ ++ L+EAE + E K +Q E + +
Sbjct: 1540 EKSEIQAALEEAEASLEHEEGKILRIQLELNQV 1572
Score = 117 bits (294), Expect = 3e-24
Identities = 175/890 (19%), Positives = 357/890 (39%), Gaps = 113/890 (12%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ +E + +E+D ++ ++KL + E + +Q +++ E + +L LQ
Sbjct: 1057 RKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDEQALAMQLQKKIKELQ 1116
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + +R S R ++E + + +
Sbjct: 1117 ARIEELEEEIE--AERASRAKAEKQRSDLSR--ELEEISERLEEAGGATSAQIEMNKKRE 1172
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K ++
Sbjct: 1173 AEFQKMRRDLEEATLQHEATAATLRKKHADSVAELG---EQIDNLQRVKQKLEKEKSEMK 1229
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K LE+ R L +L + K E+ + +L Q + E
Sbjct: 1230 MEIDDLASNMETVSKAKGNLEKMCRTLEDQLSELKTKEEEQQRLINDLTAQRARLQTESG 1289
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ DE+ V+ + + + I+EL+ +E E A++ + + ++
Sbjct: 1290 EYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHAVQSSRHDCDLLRE 1349
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
++ + LQ MS+ + EV TK + IQ T E +EE K K ++++++ +
Sbjct: 1350 QYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQDAEEH 1407
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME-------I 3789
+E + + LEK + + E D+ ++ A+ A +DKK++ + L E
Sbjct: 1408 VEAVNAKCASLEKTKQRLQNEVEDLMIDVERSNAACAALDKKQRNFDKILAEWKQKYEET 1467
Query: 3790 QANLAESDEHKRTLIDQL-------ERSRDELDHLNRVREEEEHAFANMQRRLAT----- 3933
A L S + R+L +L E S D+L+ L R + + +++ ++A
Sbjct: 1468 HAELEASQKESRSLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRI 1527
Query: 3934 ------------------AXXXXXXXXXXXXXXTRLKIA-NINRARQLEDEKNALLDEKE 4056
A L+I +N+ + D K A DE+
Sbjct: 1528 HELEKIKKQVEQEKSEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEI 1587
Query: 4057 E---------AEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN------LRD 4191
+ E +++ L+ EI + R A ++K E +N+ +L N LR+
Sbjct: 1588 DQLKRNHVRVVESMQSMLDAEIRS-RNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRN 1646
Query: 4192 VEHLQKQLEESEVAKERILQSKKKIQQELEDSSM-------ELENVRASHRDSEKRQKKF 4350
+ Q L+++++ + L+S++ ++++L E+E +RA+ +E+ +K
Sbjct: 1647 YRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKVA 1706
Query: 4351 ESQM--AEERVAV----------QKALLDRDAMS---------QELRDRETRVLSLLNEV 4467
E ++ A ERV + K L+ D QE R+ E + + +
Sbjct: 1707 EQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDA 1766
Query: 4468 DIMKEHLEES-------DRVRRSLQQELQDSISNKDDFG--------KNVHELEKAKRSL 4602
+M E L++ +R++++L+Q ++D D+ K + +LE R L
Sbjct: 1767 AMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVREL 1826
Query: 4603 EAELNDMRVQMEELEDNL------------QIAEDAR--LRLEVTNQALKSESDRAISNK 4740
E E+ + + E L Q ED + LRL+ L+++ ++ +
Sbjct: 1827 EGEVESEQKRNVETVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKV-KSYKRQ 1885
Query: 4741 DVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
EAEE+ L + R L++ELE + A S K+ + E+ ++
Sbjct: 1886 AEEAEEQSNVNLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKI 1935
Score = 72.8 bits (177), Expect = 1e-10
Identities = 100/522 (19%), Positives = 204/522 (38%), Gaps = 19/522 (3%)
Frame = +1
Query: 4234 KERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAM 4413
K + L + ++E+ + E E + S +E ++K+ E +M A+
Sbjct: 839 KIKPLLKSAETEKEMANMKEEFEKTKESLAKAEAKRKELEEKMV--------------AL 884
Query: 4414 SQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAK 4593
QE D + +V + + + +E ++ + + L+ ++++ +D + EL K
Sbjct: 885 MQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK 944
Query: 4594 RSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGL 4773
R LE E ++++ +++LE L E + E + L E + + ++++ L
Sbjct: 945 RKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEM-AGLDETIAKLTKEKKAL 1003
Query: 4774 LKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXX 4953
+ + ++L+ E+ + + K+E Q+ +LE LE +L+ +
Sbjct: 1004 QEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDL----------- 1052
Query: 4954 XEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXX 5133
+AK + L+ A +E +++QL E + +K+
Sbjct: 1053 ----------ERAKRKLEGDLKLAQESTMDIENDKQQLDE------KLKKKEF------- 1089
Query: 5134 XXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMER 5313
E L++KI Q K ++ Q ++E++ ++ ER
Sbjct: 1090 ------------EMSNLQSKIEDEQALAMQLQK-------KIKELQARIEELEEEIEAER 1130
Query: 5314 TLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEK 5493
K E ++ L R + ++ E GA S EA+ Q + L +E
Sbjct: 1131 ASRAKAEKQRSDLSRELEEISERLEEA-GGATSAQIEMNKKREAEFQKMRRDL----EEA 1185
Query: 5494 TAANRA-ARRLEKRLNDTTQQFEDEKRANEQAKELLEK-------------SNLKN---- 5619
T + A A L K+ D+ + ++ ++ K+ LEK SN++
Sbjct: 1186 TLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKA 1245
Query: 5620 -RNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
NL + ED++S +TK QR +DL +L E
Sbjct: 1246 KGNLEKMCRTLEDQLSELKTKEEEQQRLINDLTAQRARLQTE 1287
>gi|13432175|sp|P13538|MYSS_CHICK Myosin heavy chain, skeletal muscle,
adult
Length = 1939
Score = 1125 bits (2911), Expect = 0.0
Identities = 657/1888 (34%), Positives = 1054/1888 (55%), Gaps = 14/1888 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V E F+ G+I+ + +V V+ + +T+ D V NPPK+DKIEDM+ +T+L
Sbjct: 40 FVVHPKESFVKGTIQSKEGGKVTVK-TEGGETLTVKEDQVFSMNPPKYDKIEDMAMMTHL 98
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 99 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVLAYRGKKRQEAPPHIFS 158
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A + K + +
Sbjct: 159 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAASGEKKKEEQSGKMQ-- 216
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 217 ---------GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIE 267
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPNV 981
YLLEKSRV Q ERS+HIFYQI+ E + LL + +Y ++ IT+P++
Sbjct: 268 TYLLEKSRVTFQLPAERSYHIFYQIMSN-KKPELIDMLLITTNPYDYHYVSQGEITVPSI 326
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
DD +E +T +++ I+GF+ DE ++I ++ AV+ GNL+F Q+++ +QA V K
Sbjct: 327 DDQEELMATDSAIDILGFSADEKTAIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADK 386
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L+GL EL KA PR+KVG EFV K Q Q +V A+AKA YE++F W+V RI
Sbjct: 387 AAYLMGLNSAELLKALCYPRVKVGNEFVTKGQTVSQVHNSVGALAKAVYEKMFLWMVIRI 446
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 447 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H K
Sbjct: 506 KEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNN 565
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P ++++HF++VHYAG VDY+ WL KN DPLNE V+GL Q S+ +A ++
Sbjct: 566 FQKPKPAKGKAEAHFSLVHYAGTVDYNISGWLEKNKDPLNETVIGLYQKSSVKTLALLF- 624
Query: 1870 DAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHE 2049
A + G AE G + + F+TVS L +E L KLM LR+T PHFVRCIIPN
Sbjct: 625 -ATYGG--EAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMANLRSTHPHFVRCIIPNET 681
Query: 2050 KKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDG 2226
K G + LVL QLRCNGVLEGIRICR+GFP+RV + +F+ RY +L IP+ F+D
Sbjct: 682 KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRVLYADFKQRYRVLNASAIPEGQFMDS 741
Query: 2227 KESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSR 2406
K++ K++ ++D+D YR G +KVFF+ G+L LEE RD KL +I QA+CRGFL R
Sbjct: 742 KKASEKLLGSIDVDHTQYRFGHTKVFFKAGLLGLLEEMRDDKLAEIITRTQARCRGFLMR 801
Query: 2407 RLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRA 2586
Y N +++ +++W W +LF K+KPLL+ ++ E+ +E
Sbjct: 802 VEYRRMVERRESIFCIQYNVRSFMNVKHWPWMKLFFKIKPLLKSAESEKEMANMKEEFEK 861
Query: 2587 TKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYI 2766
TKE L K E +E E+K+ ++ E+ +Q Q+Q E+++ A+ ++ +L +LE
Sbjct: 862 TKEELAKSEAKRKELEEKMVVLLQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAK 921
Query: 2767 VNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXX 2946
+ ++ +R +RK + + +K +
Sbjct: 922 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 981
Query: 2947 XXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDL 3126
+ L E++ KAK +LE Q+ +LE L
Sbjct: 982 TEEMAVLDETIAKLTKEKKALQEAHQQTLDDLQVEEDKVNTLTKAKTKLEQQVDDLEGSL 1041
Query: 3127 NRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEES 3306
+E++ + +LE+ KRKL +L+ + D + + ++L+ +L K+D E+ ++ ++E
Sbjct: 1042 EQEKKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQ 1101
Query: 3307 ANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT 3486
A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L++ AT
Sbjct: 1102 ALGMQLQKKIKELQARIEELEEEIEAERTSRAKAEKHRADLSRELEEI-SERLEEAGGAT 1160
Query: 3487 MLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQL 3663
Q M++K E E +R +E+ E + K + EL +QI+ ++ + +L
Sbjct: 1161 AAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKL 1220
Query: 3664 EKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQL 3843
EK++++ E D+A + + ++A+++K + E L EI+ ++ L Q
Sbjct: 1221 EKEKSELKMEIDDLASNMESVSKAKANLEKMCRTLEDQLSEIKTKEEQNQRMINDLNTQR 1280
Query: 3844 ERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLE 4023
R + E +R EE++ + + R + K A + +
Sbjct: 1281 ARLQTETGEYSRQAEEKDALISQLSRGKQGFTQQIEELKRHLEEEIKAKNALAHALQSAR 1340
Query: 4024 DEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHL 4203
+ L ++ EE + + L++ + A + R K E Q+ EEL + + + L
Sbjct: 1341 HDCELLREQYEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1400
Query: 4204 QKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEER 4374
Q E E + + ++K+++Q E+ED +++E A+ +K+QK F+ +AE +
Sbjct: 1401 QDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMVDVERSNAACAALDKKQKNFDKILAEWK 1460
Query: 4375 VAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKD 4554
++ + +A +E R T + + N + +HLE R ++LQQE+ D
Sbjct: 1461 QKYEETQTELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEIADLTEQIA 1520
Query: 4555 DFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAIS 4734
+ GK VHELEK K+ +E E ++++ +EE E +L+ E LRL++ +KSE DR I+
Sbjct: 1521 EGGKAVHELEKVKKHVEQEKSELQASLEEAEASLEHEEGKILRLQLELNQIKSEIDRKIA 1580
Query: 4735 NKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKE 4914
KD E ++ +R L+ + +++ L+ E R ++ A+ +KK+E + E+E QL ANR+
Sbjct: 1581 EKDEEIDQLKRNHLRIVESMQSTLDAEIRSRNEALRLKKKMEGDLNEMEIQLSHANRMAA 1640
Query: 4915 EYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQ 5094
E + QI ++A + +ED+ + +R+ ++AE E+LR A E +
Sbjct: 1641 EAQKNLRNTQGTLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEVEELRGALEQTER 1700
Query: 5095 ARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRK 5265
+RK Q K++LE I Q A +K +K
Sbjct: 1701 SRKVAEQELLDATERVQLLHTQNTSLINTKKKLETDIVQIQSEMEDTIQEARNAEEKAKK 1760
Query: 5266 AQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEA 5445
A + +L E+ + E K++++++ +D ++ E E A + Q+ LEA
Sbjct: 1761 AITDAAMMAEELKKEQDTSAHLERMKKNMDQTVKDLHVRLDEAEQLALKGGKKQLQKLEA 1820
Query: 5446 KVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRN 5625
+V+ LE +++ E + A + R+ E+R+ + T Q E++++ + ++L++K +K ++
Sbjct: 1821 RVRELEGEVDSEQKRSAEAVKGVRKYERRVKELTYQCEEDRKNILRLQDLVDKLQMKVKS 1880
Query: 5626 LRRQLDEAEDEMSRERTKHRNVQREADD 5709
+RQ +EAE+ + +K R +Q E ++
Sbjct: 1881 YKRQAEEAEELSNVNLSKFRKIQHELEE 1908
Score = 164 bits (416), Expect = 2e-38
Identities = 189/922 (20%), Positives = 383/922 (41%), Gaps = 36/922 (3%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + + +++L + + ELE+ LL E D + + A+ + EE +
Sbjct: 850 KEMANMKEEFEKTKEELAKSEAKRKELEEKMVVLLQEKNDLQLQVQAEADSLADAEERCD 909
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE N L K+ R ++ EL++D++ E
Sbjct: 910 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKDIDD-------LE 961
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQ------IQHTMEG 3573
+T +V + + V + +E +L + +++ +E A + A +Q ++
Sbjct: 962 LTLAKVEKEKHATENKVKNLTEEMAVLDETIAKLTKEKKALQEAHQQTLDDLQVEEDKVN 1021
Query: 3574 KIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK 3753
+ + K K +QV++L +EQ KK R LE+ + + + + I L+ + +D+
Sbjct: 1022 TLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDE 1081
Query: 3754 KRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLAT 3933
K K + + +IQ+ + E ++ L QL++ EL R+ E EE A R
Sbjct: 1082 KLKKKDFEISQIQSKI----EDEQALGMQLQKKIKELQ--ARIEELEEEIEAERTSRAKA 1135
Query: 3934 AXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQG 4113
RL+ A A Q+E +++K EAE
Sbjct: 1136 EKHRADLSRELEEISERLEEAGGATAAQIE------MNKKREAE---------------- 1173
Query: 4114 AGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELED 4284
+ RR EE+ Q LRKK+ L +Q++ + K+++ + K +++ E++D
Sbjct: 1174 FQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDD 1233
Query: 4285 SSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNE 4464
+ +E+V + + EK + E Q++E + + + + D T+ L E
Sbjct: 1234 LASNMESVSKAKANLEKMCRTLEDQLSEIKT-------KEEQNQRMINDLNTQRARLQTE 1286
Query: 4465 VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEEL 4644
EE D + L + Q ++ +++ E KAK +L L R E L
Sbjct: 1287 TGEYSRQAEEKDALISQLSRGKQGFTQQIEELKRHLEEEIKAKNALAHALQSARHDCELL 1346
Query: 4645 EDNLQIAEDARLRL---------EVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLE 4797
+ + ++A+ L EV K E+D AI + E EE ++ L ++++D E
Sbjct: 1347 REQYEEEQEAKGELQRALSKANSEVAQWRTKYETD-AIQRTE-ELEEAKKKLAQRLQDAE 1404
Query: 4798 NELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECE 4977
+E + +++++N++ +L +E +N E++ + E
Sbjct: 1405 EHVEAVNAKCASLEKTKQRLQNEVEDLMVDVERSNAACAALDKKQKNFDKILAEWKQKYE 1464
Query: 4978 EARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGG 5157
E + E R + ++ E+ + E L + K A+GG
Sbjct: 1465 ETQTELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEIADLTEQIAEGGK 1524
Query: 5158 ISSE---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQK 5328
E K+ +E + ++ +++ E K + Q++L QI ++ +++K
Sbjct: 1525 AVHELEKVKKHVEQEKSELQASLEEAEASLEHEEGKILRLQLELNQIKSE------IDRK 1578
Query: 5329 TEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANR 5508
+ + +++ R++ + ++S + R++ AL K + +E LN + + ANR
Sbjct: 1579 IAEKDEEIDQLKRNHLRIVESMQSTLDAEIRSRNEALRLK-KKMEGDLNEMEIQLSHANR 1637
Query: 5509 AARRLEKR-------LNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSR 5667
A +K L DT +D R E KE + + L+ +++E + +
Sbjct: 1638 MAAEAQKNLRNTQGTLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEVEELRGALEQ 1697
Query: 5668 ERTKHRNVQREADDLLDANEQL 5733
+ ++E LLDA E++
Sbjct: 1698 TERSRKVAEQE---LLDATERV 1716
Score = 135 bits (341), Expect = 9e-30
Identities = 177/905 (19%), Positives = 364/905 (39%), Gaps = 136/905 (15%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ + ++ +E+D ++ ++KL + E + IQ +++ E +L LQ
Sbjct: 1056 RKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQ 1115
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + +R S R ++E + + +
Sbjct: 1116 ARIEELEEEIE--AERTSRAKAEKHRADLSR--ELEEISERLEEAGGATAAQIEMNKKRE 1171
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K L+
Sbjct: 1172 AEFQKMRRDLEEATLQHEATAAALRKKHADSTAELG---EQIDNLQRVKQKLEKEKSELK 1228
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K+ LE+ R L +L + K + + +LN Q + E
Sbjct: 1229 MEIDDLASNMESVSKAKANLEKMCRTLEDQLSEIKTKEEQNQRMINDLNTQRARLQTETG 1288
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ +E+ A ++ + + + I+EL+ +E E A+N + E ++
Sbjct: 1289 EYSRQAEEKDALISQLSRGKQGFTQQIEELKRHLEEEIKAKNALAHALQSARHDCELLRE 1348
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
++ + LQ +S+ + EV TK + IQ T E +EE K K ++++++ +
Sbjct: 1349 QYEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQDAEEH 1406
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME-------I 3789
+E + + LEK + + E D+ ++ A+ A +DKK+K + L E
Sbjct: 1407 VEAVNAKCASLEKTKQRLQNEVEDLMVDVERSNAACAALDKKQKNFDKILAEWKQKYEET 1466
Query: 3790 QANLAESDEHKRTLIDQLERSR----DELDHLNRVREEEEHAFANMQRRLATAXXXXXXX 3957
Q L S + R+L +L + + + LDHL ++ E + N+Q+ +A
Sbjct: 1467 QTELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENK----NLQQEIADLTEQIAEG 1522
Query: 3958 XXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKA 4137
++K + +E EK+ L EEAE H E +I + + + +
Sbjct: 1523 GKAVHELEKVK-------KHVEQEKSELQASLEEAEASLEHEEGKILRLQLELNQIKSEI 1575
Query: 4138 EESV---NQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE-- 4302
+ + ++++++L++ +LR VE +Q L+ ++ L+ KKK++ +L + ++L
Sbjct: 1576 DRKIAEKDEEIDQLKRNHLRIVESMQSTLDAEIRSRNEALRLKKKMEGDLNEMEIQLSHA 1635
Query: 4303 ------------NVRASHRDS---------------------EKRQKKFESQMAEERVAV 4383
N + + +D+ E+R ++++ E R A+
Sbjct: 1636 NRMAAEAQKNLRNTQGTLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEVEELRGAL 1695
Query: 4384 QKALLDRDAMSQELRDRETRV-------LSLLN-----EVDIMKEHLEESDRVR--RSLQ 4521
++ R QEL D RV SL+N E DI++ E D ++ R+ +
Sbjct: 1696 EQTERSRKVAEQELLDATERVQLLHTQNTSLINTKKKLETDIVQIQSEMEDTIQEARNAE 1755
Query: 4522 QELQDSISN--------KDDFGKNVHELEKAKRSLEAELNDMRVQMEELED-NLQIAEDA 4674
++ + +I++ K + + H LE+ K++++ + D+ V+++E E L+ +
Sbjct: 1756 EKAKKAITDAAMMAEELKKEQDTSAH-LERMKKNMDQTVKDLHVRLDEAEQLALKGGKKQ 1814
Query: 4675 RLRLEVTNQALKSESD-----------------RAISNKDVEAEEKRRGLLK-------- 4779
+LE + L+ E D R + + EE R+ +L+
Sbjct: 1815 LQKLEARVRELEGEVDSEQKRSAEAVKGVRKYERRVKELTYQCEEDRKNILRLQDLVDKL 1874
Query: 4780 -----------------------QIRDLENELE-------------NEKRGKSGAVSHRK 4851
+ R +++ELE N+ R KS + H K
Sbjct: 1875 QMKVKSYKRQAEEAEELSNVNLSKFRKIQHELEEAEERADIAESQVNKLRVKSREI-HGK 1933
Query: 4852 KIENQ 4866
KIE +
Sbjct: 1934 KIEEE 1938
Score = 126 bits (317), Expect = 6e-27
Identities = 146/760 (19%), Positives = 314/760 (41%), Gaps = 49/760 (6%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + E+ +++ + + +R +LE++ QE+ D+ ++ S AD ++
Sbjct: 849 EKEMANMKEEFEKTKEELAKSEAKRKELEEKMVVLLQEKNDLQLQVQAEADSLADAEERC 908
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ + +E L + + DE L + ++ E A ++
Sbjct: 909 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 968
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ T K+ N+ + DE A L ++++A +
Sbjct: 969 KE---------------KHATENKVKNLTEEMAVLDETIAKLTKEKKA----------LQ 1003
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
A Q + + E+ VN L + + K + V+ L+ LE+ + + + ++K+K++ +L
Sbjct: 1004 EAHQQTLDDLQVEEDKVNT-LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDL 1062
Query: 4279 E---DSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL 4449
+ DS M+LEN + D + ++K FE + ++ ++AL + +++++ + R+
Sbjct: 1063 KLAHDSIMDLENDK-QQLDEKLKKKDFEISQIQSKIEDEQAL--GMQLQKKIKELQARIE 1119
Query: 4450 SLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFG-----------KNVHELEKAKR 4596
L E++ + ++++ R L +EL++ ++ G K E +K +R
Sbjct: 1120 ELEEEIEAERTSRAKAEKHRADLSRELEEISERLEEAGGATAAQIEMNKKREAEFQKMRR 1179
Query: 4597 SL-EAELN-------------DMRVQMEELEDNLQIA------EDARLRLEVTNQALKSE 4716
L EA L D ++ E DNLQ E + L++E+ + A E
Sbjct: 1180 DLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNME 1239
Query: 4717 SDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEV 4896
S +S E+ R L Q+ +++ + E +R + + R +++ + GE +Q E
Sbjct: 1240 S---VSKAKANLEKMCRTLEDQLSEIKTKEEQNQRMINDLNTQRARLQTETGEYSRQAEE 1296
Query: 4897 ANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAV----EAEREQ 5064
+ L + E + EE +AK +A L+ A + E E+E
Sbjct: 1297 KDALISQLSRGKQGFTQQIEELKRHLEEEIKAKNALAHALQSARHDCELLREQYEEEQEA 1356
Query: 5065 LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCEL 5244
E L +A + + E K++L ++ + C
Sbjct: 1357 KGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCAS 1416
Query: 5245 AIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKI----TELESGAQS 5412
+++ Q ++E + D+ + ++++ ++ ++K K TELE+ +
Sbjct: 1417 LEKTKQRLQNEVEDLMVDVERSNAACAALDKKQKNFDKILAEWKQKYEETQTELEASQKE 1476
Query: 5413 RARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKE 5592
+ K Y E ++E R + L++ + D T+Q + +A + ++
Sbjct: 1477 SRSLSTELFKMKNAYEESLDHLE-----TLKRENKNLQQEIADLTEQIAEGGKAVHELEK 1531
Query: 5593 LLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ + + L+ L+EAE + E K +Q E + +
Sbjct: 1532 VKKHVEQEKSELQASLEEAEASLEHEEGKILRLQLELNQI 1571
Score = 70.5 bits (171), Expect = 5e-10
Identities = 104/519 (20%), Positives = 196/519 (37%), Gaps = 16/519 (3%)
Frame = +1
Query: 4234 KERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAM 4413
K + L + ++E+ + E E + SE ++K+ E +M L A
Sbjct: 838 KIKPLLKSAESEKEMANMKEEFEKTKEELAKSEAKRKELEEKMVVLLQEKNDLQLQVQAE 897
Query: 4414 SQELRDRETRVLSLLN-------EVDIMKEHLEESDRVRRSL---QQELQDSISNKDDFG 4563
+ L D E R L+ ++ + E E+ + + L +++L+D S +
Sbjct: 898 ADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECS---ELK 954
Query: 4564 KNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
K++ +LE +E E + +++ L + + + ++ +L +AL+ + + +
Sbjct: 955 KDIDDLELTLAKVEKEKHATENKVKNLTEEMAVLDETIAKLTKEKKALQEAHQQTLDDLQ 1014
Query: 4744 VEAEE------KRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANR 4905
VE ++ + L +Q+ DLE LE EK+ R +E +LE L++A+
Sbjct: 1015 VEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKK-------LRMDLERAKRKLEGDLKLAHD 1067
Query: 4906 LKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEG 5085
+ + E + + ED AL + +K + ++A E+L E E
Sbjct: 1068 SIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQARIEELEEEIEA 1127
Query: 5086 LMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRK 5265
RAK ++ R LE +
Sbjct: 1128 --------------ERTSRAKAEKHRADLSRELE-------------------------E 1148
Query: 5266 AQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEA 5445
+LE+ + + +N+K EAE Q + R +LE A + A AAL
Sbjct: 1149 ISERLEEAGGATAAQIEMNKKREAEFQKMRR----------DLEE-ATLQHEATAAALRK 1197
Query: 5446 KVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRN 5625
K D G++ R ++LEK ++ + +D +E + N
Sbjct: 1198 K---HADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDD-------LASNMESVSKAKAN 1247
Query: 5626 LRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
L + ED++S +TK QR +DL +L E
Sbjct: 1248 LEKMCRTLEDQLSEIKTKEEQNQRMINDLNTQRARLQTE 1286
Score = 54.7 bits (130), Expect = 3e-05
Identities = 78/349 (22%), Positives = 134/349 (38%), Gaps = 51/349 (14%)
Frame = +1
Query: 4852 KIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADR 5031
KI+ + E + E+AN +KEE+ + ++ +E + LL+E +
Sbjct: 838 KIKPLLKSAESEKEMAN-MKEEFEKTKEELAKSEAK-------RKELEEKMVVLLQEKND 889
Query: 5032 KFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXX 5211
V+AE + L +A E Q K K +LEAKI +
Sbjct: 890 LQLQVQAEADSLADAEERCDQLIKT----------------------KIQLEAKIKEVTE 927
Query: 5212 XXXXXQS-NCELAIDKQRKAQVQLEQITTDLS-MERTLNQKTEAEKQSLERSNRDYKAKI 5385
+ N EL K+RK + + ++ D+ +E TL K E EK + E ++ ++
Sbjct: 928 RAEDEEEINAELTA-KKRKLEDECSELKKDIDDLELTL-AKVEKEKHATENKVKNLTEEM 985
Query: 5386 TELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDE 5565
L+ + + A EA Q L+D L VE + +A +LE++++D E E
Sbjct: 986 AVLDETIAKLTKEKKALQEAHQQTLDD-LQVEEDKVNTLTKAKTKLEQQVDDLEGSLEQE 1044
Query: 5566 KRAN---EQAKELLE----------------KSNL------------------------- 5613
K+ E+AK LE K L
Sbjct: 1045 KKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALG 1104
Query: 5614 -----KNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
K + L+ +++E E+E+ ERT ++ DL E+++ L
Sbjct: 1105 MQLQKKIKELQARIEELEEEIEAERTSRAKAEKHRADLSRELEEISERL 1153
>gi|24584702|ref|NP_724004.1| CG17927-PD [Drosophila melanogaster]
gi|22946664|gb|AAN10963.1| CG17927-PD [Drosophila melanogaster]
Length = 1962
Score = 1125 bits (2910), Expect = 0.0
Identities = 679/1916 (35%), Positives = 1081/1916 (55%), Gaps = 31/1916 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K CW+PD+ EG+L+G IK D V V L + + +D +Q+ NPPK++K EDMS
Sbjct: 35 KKSCWIPDEKEGYLLGEIKATKGDIVSVGLQGGETR-DLKKDLLQQVNPPKYEKAEDMSN 93
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LTYLN+ASVLHNL+ RYY+ LIYTYSGLFCV INPYK+ P+Y+ + ++GK+R+E+PP
Sbjct: 94 LTYLNDASVLHNLRQRYYNKLIYTYSGLFCVAINPYKRYPVYTNRCAKMYRGKRRNEVPP 153
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIFAI+D AY ML +QS+L TGESGAGKTENTKKVI Y A V +K + AA+
Sbjct: 154 HIFAISDGAYVDMLTNHVNQSMLITGESGAGKTENTKKVIAYFATVGA---SKKTDEAAK 210
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
G LE Q++Q NP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++G
Sbjct: 211 SK-----------GSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFGPTGKLAG 259
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLL-EGVDNYRFLVNRGITL 972
A+IE YLLEK+RV+ Q ERS+HIFYQI+ G K LL + + +Y + +T+
Sbjct: 260 ADIETYLLEKARVISQQSLERSYHIFYQIMSGSVPGVKDICLLTDNIYDYHIVSQGKVTV 319
Query: 973 PNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRV 1152
++DD +EF T + I+GF E + R+ +AV+ +G ++F Q + +QA +
Sbjct: 320 ASIDDAEEFSLTDQAFDILGFTKQEKEDVYRITAAVMHMGGMKFKQRGREEQAEQDGEEE 379
Query: 1153 IQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLV 1332
+V L G EL K L+PRIKVG EFV + +N +Q ++ A+ K ++RLFKWLV
Sbjct: 380 GGRVSKLFGCDTAELYKNLLKPRIKVGNEFVTQGRNVQQVTNSIGALCKGVFDRLFKWLV 439
Query: 1333 TRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQE 1512
+ N++LD T ++ FIG+LDIAGFEIF+ N FEQ+CIN+TNEKLQQ FN+ MF+LEQE
Sbjct: 440 KKCNETLD-TQQKRQHFIGVLDIAGFEIFEYNGFEQLCINFTNEKLQQFFNHHMFVLEQE 498
Query: 1513 EYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NK 1689
EY+REGI+W FIDFG+DL IDLIEKPMG+L++L+EE +FPKA D++F EKL TH K
Sbjct: 499 EYKREGIDWAFIDFGMDLLACIDLIEKPMGILSILEEESMFPKATDQTFSEKLTNTHLGK 558
Query: 1690 HPKFIVPDM----RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVA 1857
F P + +HFA+ HYAG V Y+ WL KN DPLN+ VV + S + +
Sbjct: 559 SAPFQKPKPPKPGQQAAHFAIAHYAGCVSYNITGWLEKNKDPLNDTVVDQFKKSQNKLLI 618
Query: 1858 GIWKDAEFAGICAAEMNETAFGMRSRK-GMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCI 2034
I+ A+ AG E A G R +K G F TVS +KEQL LMTTLR+T PHFVRCI
Sbjct: 619 EIF--ADHAGQSGG--GEQAKGGRGKKGGGFATVSSAYKEQLNSLMTTLRSTQPHFVRCI 674
Query: 2035 IPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKN 2214
IPN K+ G ++++LV+ QL CNGVLEGIRICR+GFPNR+ + +F+ RY+IL P I K
Sbjct: 675 IPNEMKQPGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKMRYQILNPKGI-KG 733
Query: 2215 FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRG 2394
D K+ + +I + +++ + YR+G +KVFFR GVL +EE RD +L ++ QA RG
Sbjct: 734 IEDPKKCTKVLIESTELNDDQYRLGNTKVFFRAGVLGQMEEFRDERLGKIMSWMQAWARG 793
Query: 2395 FLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDD 2574
+LSR+ + N YL+LR W W++L+ KVKPLL V+R +DEI A+ +
Sbjct: 794 YLSRKGFKKLQEQRVALKVVQRNLRKYLQLRTWPWYKLWQKVKPLLNVSRIEDEI-ARLE 852
Query: 2575 ELRATKERLLKMEHDFRENEKKLD-QVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQ 2751
E E L E R+ + L+ +++ E+ + + L E + + +L +
Sbjct: 853 EKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQDYQERNAKLTAQKN 912
Query: 2752 ELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQ 2931
+LE + D+++RL+ ++K + + DK D
Sbjct: 913 DLENQLRDIQERLTQEEDARNQLFQQKKKADQEISGLKKDIEDLELNVQKAEQDKATKDH 972
Query: 2932 XXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHE 3111
+ + +L E++ H K K +LE L E
Sbjct: 973 QIRNLNDEIAHQDELINKLNKEKKMQGETNQKTGEELQAAEDKINHLNKVKAKLEQTLDE 1032
Query: 3112 LEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTR 3291
LE L RE++ + ++E+ KRK+ +L+ +++ +A+ +EL + ++D+EL +
Sbjct: 1033 LEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVADLERNKKELEQTIQRKDKELSSITAK 1092
Query: 3292 YDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDK 3471
++E V Q+Q++++Q I+EL E++E ER AR KAE R ++ +LE++ G+ L++
Sbjct: 1093 LEDEQVVVLKHQRQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEEL-GERLEE 1151
Query: 3472 VDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKK 3648
AT Q +L +++ E++ +R +E+ E + + K + V E+ +Q++Q K
Sbjct: 1152 AGGATSAQIELNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNK 1211
Query: 3649 QRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRT 3828
+++ EK++N+ + D+ + + +A +K K + L E+Q+ L DE RT
Sbjct: 1212 LKAKAEKEKNEYYGQLNDLRAGVDHITNEKAAQEKIAKQLQHTLNEVQSKL---DETNRT 1268
Query: 3829 LIDQLERSRDEL----DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIA 3996
L D + S+ +L L R EE E + + + + +R +
Sbjct: 1269 LND-FDASKKKLSIENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERAT 1327
Query: 3997 NINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHAARQGAGEARRKAEE---SVNQQLE 4164
+ + R LE + + L ++ +EEAEG +A L++++ A A R K E + +++LE
Sbjct: 1328 LLGKFRNLEHDLDNLREQVEEEAEG-KADLQRQLSKANAEAQVWRSKYESDGVARSEELE 1386
Query: 4165 ELRKKNLRDVEHLQKQLEESEVAKERILQ-------SKKKIQQELEDSSMELENVRASHR 4323
E ++K LQ +L E+E E + Q +K+++ E+ED +E++ A
Sbjct: 1387 EAKRK-------LQARLAEAEETIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIAN 1439
Query: 4324 DSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDR 4503
+EK+QK F+ + E ++ V + DA +E R+ T + L + +E LE R
Sbjct: 1440 AAEKKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRR 1499
Query: 4504 VRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLR 4683
++L E++D + + G+N+HE+EKA++ LEAE ++++ +EE E L+ E+ LR
Sbjct: 1500 ENKNLADEVKDLLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLR 1559
Query: 4684 LEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIEN 4863
++ ++ E DR I K+ E E R+ + + ++ LE E +GK+ A+ +KK+E
Sbjct: 1560 AQLELSQVRQEIDRRIQEKEEEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEA 1619
Query: 4864 QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRA 5043
I ELE L+ AN+ E + Q EE ++A++D L ++R+ A
Sbjct: 1620 DINELEIALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANA 1679
Query: 5044 VEAEREQ----LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXX 5211
++ E E+ L +A+ G QA ++ A+ IS+ KR+LE+++
Sbjct: 1680 LQNELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISA-AKRKLESELQTLHS 1738
Query: 5212 XXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITE 5391
+ + + +K +KA V ++ +L E+ Q E +++LE+ ++ + ++ E
Sbjct: 1739 DLDELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDE 1798
Query: 5392 LESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKR 5571
E+ A + + LE +V+ LE++L+ E + A + R+ E+R+ + + Q E++++
Sbjct: 1799 AEANALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRK 1858
Query: 5572 ANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQR---EADDLLDANEQ 5730
+E+ ++L++K K + +RQ++EAE+ + K R Q+ EA++ D EQ
Sbjct: 1859 NHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQ 1914
Score = 155 bits (391), Expect = 1e-35
Identities = 179/950 (18%), Positives = 386/950 (39%), Gaps = 62/950 (6%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDE 3267
RLE + + E+ E + + ELE KLLAE D L+ + G +++
Sbjct: 850 RLEEKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQD---------- 899
Query: 3268 ELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEK 3447
Y E +A +T Q D++ + +++E + E +ARN+ +++ ++
Sbjct: 900 --------YQERNAKLTA---QKNDLENQLRDIQERLTQEEDARNQLFQQKKKADQEISG 948
Query: 3448 VKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+K D+ D + + KD ++ I Q + K+ ++K ++ +
Sbjct: 949 LKKDIEDLELNVQKAEQDKATKDHQIRNLNDEIAH-QDELINKLNKEKKMQGETNQKTGE 1007
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAE 3807
+++ + + + L K + + +Q ++ + + R D++K ++ E L Q +A+
Sbjct: 1008 ELQAAEDKINHLNKVKAKLEQTLDELEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVAD 1067
Query: 3808 SDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL 3987
+ +K+ L ++R EL + E+E+ QR++
Sbjct: 1068 LERNKKELEQTIQRKDKELSSITAKLEDEQVVVLKHQRQIKELQA--------------- 1112
Query: 3988 KIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEE 4167
R +LE+E A + +AE RA L +E+ + GE +A + + Q+E
Sbjct: 1113 ------RIEELEEEVEAERQARAKAEKQRADLAREL----EELGERLEEAGGATSAQIE- 1161
Query: 4168 LRKKNLRDVEHLQKQLEESEVAKERILQS-KKKIQQELEDSSMELENVRASHRDSEKRQK 4344
L KK ++ L++ LEE+ + E L + +KK + + + +++ + +EK +
Sbjct: 1162 LNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNKLKAKAEKEKN 1221
Query: 4345 KFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQ 4524
++ Q+ + R V ++ A + + + + + +++D L + D ++ L
Sbjct: 1222 EYYGQLNDLRAGVDHITNEKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSI 1281
Query: 4525 ELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE--------------LE---DN 4653
E D + ++ V +L K K SL +L D + +E LE DN
Sbjct: 1282 ENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERATLLGKFRNLEHDLDN 1341
Query: 4654 L--QIAEDARLRLEVTNQALKSESDRAISNKDVEA---------EEKRRGLLKQIRDLEN 4800
L Q+ E+A + ++ Q K+ ++ + E+ EE +R L ++ + E
Sbjct: 1342 LREQVEEEAEGKADLQRQLSKANAEAQVWRSKYESDGVARSEELEEAKRKLQARLAEAEE 1401
Query: 4801 ELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEE 4980
+E+ + G ++++ ++ +L+ +++ AN + E++++ ++
Sbjct: 1402 TIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIANAAEKKQKAFDKIIGEWKLKVDD 1461
Query: 4981 ARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGG-G 5157
+ R + ++ E+ +E E + + K +GG
Sbjct: 1462 LAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGRN 1521
Query: 5158 ISSEEK--RRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKT 5331
I EK +RLEA+ + ++ E +K +AQ++L Q+ ++ +R + +K
Sbjct: 1522 IHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEI--DRRIQEKE 1579
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRARA--QMAALEAKVQYLEDQLNVEGQEKTAAN 5505
E + + + R + LE+ A+ +A A LEA + LE L+ + A
Sbjct: 1580 EEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQ 1639
Query: 5506 RAARRLEKRLNDTTQQFEDEKR----------------------------ANEQAKELLE 5601
+ +R +++L D E+E+R EQA
Sbjct: 1640 KNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRR 1699
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
++ + + QL+E + + R ++ E L ++L E N
Sbjct: 1700 QAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDELLNEAKN 1749
Score = 82.4 bits (202), Expect = 1e-13
Identities = 82/418 (19%), Positives = 183/418 (43%), Gaps = 25/418 (5%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L +Q+ E ++++ + + LE K +L A LE+++ L ++ KV +L + +E
Sbjct: 1511 LLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQE 1570
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ ++ +EE N ++ Q +D ++ +E E + +A ++++ A + ++
Sbjct: 1571 IDRRIQEKEEEFENTR------KNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINEL 1624
Query: 3451 KGDVLDKVDEATM-LQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+ LD ++A Q + R +++ + A+E+ Q + EQ R+ L +
Sbjct: 1625 E-IALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDA-REQLGISERRANALQN 1682
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL-- 3801
++E+ + Q ++ + QA+QE AD +++ + A A I ++ E+ L + ++L
Sbjct: 1683 ELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDE 1742
Query: 3802 ----AESDEHKRT--------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
A++ E K L D+L +D ++R+ E +Q RL A
Sbjct: 1743 LLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAEAN 1802
Query: 3946 XXXXXXXXXXXTRLKIANIN------RARQLEDEKNALLDEKEEAE-GLRAHLEKEIHAA 4104
++ + + R + +KN E+ E ++ +++ H
Sbjct: 1803 ALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRKNHER 1862
Query: 4105 RQGAGEARRKAEESVNQQLEELRK---KNLRDVEHLQKQLEESEVAKERILQSKKKIQ 4269
Q + ++ ++ +Q+EE + NL Q++LEE+E + Q+ K +
Sbjct: 1863 MQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQAISKFR 1920
>gi|28574239|ref|NP_523587.4| CG17927-PH [Drosophila melanogaster]
gi|22946667|gb|AAN10966.1| CG17927-PH [Drosophila melanogaster]
Length = 1962
Score = 1125 bits (2910), Expect = 0.0
Identities = 679/1916 (35%), Positives = 1081/1916 (55%), Gaps = 31/1916 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K CW+PD+ EG+L+G IK D V V L + + +D +Q+ NPPK++K EDMS
Sbjct: 35 KKSCWIPDEKEGYLLGEIKATKGDIVSVGLQGGETR-DLKKDLLQQVNPPKYEKAEDMSN 93
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LTYLN+ASVLHNL+ RYY+ LIYTYSGLFCV INPYK+ P+Y+ + ++GK+R+E+PP
Sbjct: 94 LTYLNDASVLHNLRQRYYNKLIYTYSGLFCVAINPYKRYPVYTNRCAKMYRGKRRNEVPP 153
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIFAI+D AY ML +QS+L TGESGAGKTENTKKVI Y A V +K + AA+
Sbjct: 154 HIFAISDGAYVDMLTNHVNQSMLITGESGAGKTENTKKVIAYFATVGA---SKKTDEAAK 210
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
G LE Q++Q NP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++G
Sbjct: 211 SK-----------GSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFGPTGKLAG 259
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLL-EGVDNYRFLVNRGITL 972
A+IE YLLEK+RV+ Q ERS+HIFYQI+ G K LL + + +Y + +T+
Sbjct: 260 ADIETYLLEKARVISQQSLERSYHIFYQIMSGSVPGVKDICLLTDNIYDYHIVSQGKVTV 319
Query: 973 PNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRV 1152
++DD +EF T + I+GF E + R+ +AV+ +G ++F Q + +QA +
Sbjct: 320 ASIDDAEEFSLTDQAFDILGFTKQEKEDVYRITAAVMHMGGMKFKQRGREEQAEQDGEEE 379
Query: 1153 IQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLV 1332
+V L G EL K L+PRIKVG EFV + +N +Q ++ A+ K ++RLFKWLV
Sbjct: 380 GGRVSKLFGCDTAELYKNLLKPRIKVGNEFVTQGRNVQQVTNSIGALCKGVFDRLFKWLV 439
Query: 1333 TRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQE 1512
+ N++LD T ++ FIG+LDIAGFEIF+ N FEQ+CIN+TNEKLQQ FN+ MF+LEQE
Sbjct: 440 KKCNETLD-TQQKRQHFIGVLDIAGFEIFEYNGFEQLCINFTNEKLQQFFNHHMFVLEQE 498
Query: 1513 EYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NK 1689
EYQREGIEW FIDFG+DLQ IDLIEKPMG+L++L+EE +FPKA D++F EKL TH K
Sbjct: 499 EYQREGIEWTFIDFGMDLQLCIDLIEKPMGILSILEEESMFPKATDQTFSEKLTNTHLGK 558
Query: 1690 HPKFIVPDM----RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVA 1857
F P + +HFA+ HYAG V Y+ WL KN DPLN+ VV + S + +
Sbjct: 559 SAPFQKPKPPKPGQQAAHFAIAHYAGCVSYNITGWLEKNKDPLNDTVVDQFKKSQNKLLI 618
Query: 1858 GIWKDAEFAGICAAEMNETAFGMRSRK-GMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCI 2034
I+ A+ AG E A G R +K G F TVS +KEQL LMTTLR+T PHFVRCI
Sbjct: 619 EIF--ADHAGQSGG--GEQAKGGRGKKGGGFATVSSAYKEQLNSLMTTLRSTQPHFVRCI 674
Query: 2035 IPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKN 2214
IPN K+ G ++++LV+ QL CNGVLEGIRICR+GFPNR+ + +F+ RY+I+ P ++ +
Sbjct: 675 IPNEMKQPGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKMRYKIMCPKLL-QG 733
Query: 2215 FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRG 2394
K++ +I +D+ + YR+G +KVFFR GVL +EE RD +L ++ QA RG
Sbjct: 734 VEKDKKATEIIIKFIDLPEDQYRLGNTKVFFRAGVLGQMEEFRDERLGKIMSWMQAWARG 793
Query: 2395 FLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDD 2574
+LSR+ + N YL+LR W W++L+ KVKPLL V+R +DEI A+ +
Sbjct: 794 YLSRKGFKKLQEQRVALKVVQRNLRKYLQLRTWPWYKLWQKVKPLLNVSRIEDEI-ARLE 852
Query: 2575 ELRATKERLLKMEHDFRENEKKLD-QVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQ 2751
E E L E R+ + L+ +++ E+ + + L E + + +L +
Sbjct: 853 EKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQDYQERNAKLTAQKN 912
Query: 2752 ELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQ 2931
+LE + D+++RL+ ++K + + DK D
Sbjct: 913 DLENQLRDIQERLTQEEDARNQLFQQKKKADQEISGLKKDIEDLELNVQKAEQDKATKDH 972
Query: 2932 XXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHE 3111
+ + +L E++ H K K +LE L E
Sbjct: 973 QIRNLNDEIAHQDELINKLNKEKKMQGETNQKTGEELQAAEDKINHLNKVKAKLEQTLDE 1032
Query: 3112 LEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTR 3291
LE L RE++ + ++E+ KRK+ +L+ +++ +A+ +EL + ++D+EL +
Sbjct: 1033 LEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVADLERNKKELEQTIQRKDKELSSITAK 1092
Query: 3292 YDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDK 3471
++E V Q+Q++++Q I+EL E++E ER AR KAE R ++ +LE++ G+ L++
Sbjct: 1093 LEDEQVVVLKHQRQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEEL-GERLEE 1151
Query: 3472 VDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKK 3648
AT Q +L +++ E++ +R +E+ E + + K + V E+ +Q++Q K
Sbjct: 1152 AGGATSAQIELNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNK 1211
Query: 3649 QRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRT 3828
+++ EK++N+ + D+ + + +A +K K + L E+Q+ L DE RT
Sbjct: 1212 LKAKAEKEKNEYYGQLNDLRAGVDHITNEKAAQEKIAKQLQHTLNEVQSKL---DETNRT 1268
Query: 3829 LIDQLERSRDEL----DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIA 3996
L D + S+ +L L R EE E + + + + +R +
Sbjct: 1269 LND-FDASKKKLSIENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERAT 1327
Query: 3997 NINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHAARQGAGEARRKAEE---SVNQQLE 4164
+ + R LE + + L ++ +EEAEG +A L++++ A A R K E + +++LE
Sbjct: 1328 LLGKFRNLEHDLDNLREQVEEEAEG-KADLQRQLSKANAEAQVWRSKYESDGVARSEELE 1386
Query: 4165 ELRKKNLRDVEHLQKQLEESEVAKERILQ-------SKKKIQQELEDSSMELENVRASHR 4323
E ++K LQ +L E+E E + Q +K+++ E+ED +E++ A
Sbjct: 1387 EAKRK-------LQARLAEAEETIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIAN 1439
Query: 4324 DSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDR 4503
+EK+QK F+ + E ++ V + DA +E R+ T + L + +E LE R
Sbjct: 1440 AAEKKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRR 1499
Query: 4504 VRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLR 4683
++L E++D + + G+N+HE+EKA++ LEAE ++++ +EE E L+ E+ LR
Sbjct: 1500 ENKNLADEVKDLLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLR 1559
Query: 4684 LEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIEN 4863
++ ++ E DR I K+ E E R+ + + ++ LE E +GK+ A+ +KK+E
Sbjct: 1560 AQLELSQVRQEIDRRIQEKEEEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEA 1619
Query: 4864 QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRA 5043
I ELE L+ AN+ E + Q EE ++A++D L ++R+ A
Sbjct: 1620 DINELEIALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANA 1679
Query: 5044 VEAEREQ----LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXX 5211
++ E E+ L +A+ G QA ++ A+ IS+ KR+LE+++
Sbjct: 1680 LQNELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISA-AKRKLESELQTLHS 1738
Query: 5212 XXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITE 5391
+ + + +K +KA V ++ +L E+ Q E +++LE+ ++ + ++ E
Sbjct: 1739 DLDELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDE 1798
Query: 5392 LESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKR 5571
E+ A + + LE +V+ LE++L+ E + A + R+ E+R+ + + Q E++++
Sbjct: 1799 AEANALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRK 1858
Query: 5572 ANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQR---EADDLLDANEQ 5730
+E+ ++L++K K + +RQ++EAE+ + K R Q+ EA++ D EQ
Sbjct: 1859 NHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQ 1914
Score = 155 bits (391), Expect = 1e-35
Identities = 179/950 (18%), Positives = 386/950 (39%), Gaps = 62/950 (6%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDE 3267
RLE + + E+ E + + ELE KLLAE D L+ + G +++
Sbjct: 850 RLEEKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQD---------- 899
Query: 3268 ELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEK 3447
Y E +A +T Q D++ + +++E + E +ARN+ +++ ++
Sbjct: 900 --------YQERNAKLTA---QKNDLENQLRDIQERLTQEEDARNQLFQQKKKADQEISG 948
Query: 3448 VKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+K D+ D + + KD ++ I Q + K+ ++K ++ +
Sbjct: 949 LKKDIEDLELNVQKAEQDKATKDHQIRNLNDEIAH-QDELINKLNKEKKMQGETNQKTGE 1007
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAE 3807
+++ + + + L K + + +Q ++ + + R D++K ++ E L Q +A+
Sbjct: 1008 ELQAAEDKINHLNKVKAKLEQTLDELEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVAD 1067
Query: 3808 SDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL 3987
+ +K+ L ++R EL + E+E+ QR++
Sbjct: 1068 LERNKKELEQTIQRKDKELSSITAKLEDEQVVVLKHQRQIKELQA--------------- 1112
Query: 3988 KIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEE 4167
R +LE+E A + +AE RA L +E+ + GE +A + + Q+E
Sbjct: 1113 ------RIEELEEEVEAERQARAKAEKQRADLAREL----EELGERLEEAGGATSAQIE- 1161
Query: 4168 LRKKNLRDVEHLQKQLEESEVAKERILQS-KKKIQQELEDSSMELENVRASHRDSEKRQK 4344
L KK ++ L++ LEE+ + E L + +KK + + + +++ + +EK +
Sbjct: 1162 LNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNKLKAKAEKEKN 1221
Query: 4345 KFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQ 4524
++ Q+ + R V ++ A + + + + + +++D L + D ++ L
Sbjct: 1222 EYYGQLNDLRAGVDHITNEKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSI 1281
Query: 4525 ELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE--------------LE---DN 4653
E D + ++ V +L K K SL +L D + +E LE DN
Sbjct: 1282 ENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERATLLGKFRNLEHDLDN 1341
Query: 4654 L--QIAEDARLRLEVTNQALKSESDRAISNKDVEA---------EEKRRGLLKQIRDLEN 4800
L Q+ E+A + ++ Q K+ ++ + E+ EE +R L ++ + E
Sbjct: 1342 LREQVEEEAEGKADLQRQLSKANAEAQVWRSKYESDGVARSEELEEAKRKLQARLAEAEE 1401
Query: 4801 ELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEE 4980
+E+ + G ++++ ++ +L+ +++ AN + E++++ ++
Sbjct: 1402 TIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIANAAEKKQKAFDKIIGEWKLKVDD 1461
Query: 4981 ARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGG-G 5157
+ R + ++ E+ +E E + + K +GG
Sbjct: 1462 LAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGRN 1521
Query: 5158 ISSEEK--RRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKT 5331
I EK +RLEA+ + ++ E +K +AQ++L Q+ ++ +R + +K
Sbjct: 1522 IHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEI--DRRIQEKE 1579
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRARA--QMAALEAKVQYLEDQLNVEGQEKTAAN 5505
E + + + R + LE+ A+ +A A LEA + LE L+ + A
Sbjct: 1580 EEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQ 1639
Query: 5506 RAARRLEKRLNDTTQQFEDEKR----------------------------ANEQAKELLE 5601
+ +R +++L D E+E+R EQA
Sbjct: 1640 KNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRR 1699
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
++ + + QL+E + + R ++ E L ++L E N
Sbjct: 1700 QAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDELLNEAKN 1749
Score = 82.4 bits (202), Expect = 1e-13
Identities = 82/418 (19%), Positives = 183/418 (43%), Gaps = 25/418 (5%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L +Q+ E ++++ + + LE K +L A LE+++ L ++ KV +L + +E
Sbjct: 1511 LLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQE 1570
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ ++ +EE N ++ Q +D ++ +E E + +A ++++ A + ++
Sbjct: 1571 IDRRIQEKEEEFENTR------KNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINEL 1624
Query: 3451 KGDVLDKVDEATM-LQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+ LD ++A Q + R +++ + A+E+ Q + EQ R+ L +
Sbjct: 1625 E-IALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDA-REQLGISERRANALQN 1682
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL-- 3801
++E+ + Q ++ + QA+QE AD +++ + A A I ++ E+ L + ++L
Sbjct: 1683 ELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDE 1742
Query: 3802 ----AESDEHKRT--------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
A++ E K L D+L +D ++R+ E +Q RL A
Sbjct: 1743 LLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAEAN 1802
Query: 3946 XXXXXXXXXXXTRLKIANIN------RARQLEDEKNALLDEKEEAE-GLRAHLEKEIHAA 4104
++ + + R + +KN E+ E ++ +++ H
Sbjct: 1803 ALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRKNHER 1862
Query: 4105 RQGAGEARRKAEESVNQQLEELRK---KNLRDVEHLQKQLEESEVAKERILQSKKKIQ 4269
Q + ++ ++ +Q+EE + NL Q++LEE+E + Q+ K +
Sbjct: 1863 MQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQAISKFR 1920
>gi|47575800|ref|NP_001001244.1| myosin heavy chain [Xenopus
tropicalis]
gi|45595719|gb|AAH67305.1| Myosin heavy chain [Xenopus tropicalis]
Length = 1935
Score = 1125 bits (2910), Expect = 0.0
Identities = 660/1892 (34%), Positives = 1068/1892 (55%), Gaps = 18/1892 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V D E ++ G + + ++ V+ D R VT+ + + NPPKFDKIEDM+ +T+L
Sbjct: 38 FVDDVKELYVKGMVTAREDGKITVK-TDDGRTVTVKENQIYPQNPPKFDKIEDMAMMTHL 96
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
NEASVL+NLK+RY + +IYTYSGLFC +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 97 NEASVLYNLKERYAAWMIYTYSGLFCATVNPYKWLPVYNPEVVAGYRGKKRMEAPPHIFS 156
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
++D AY++ML +RE+QS+L TGESGAGKT NTK+VIQY A +A K ++ + Q
Sbjct: 157 LSDNAYQAMLTDRENQSVLITGESGAGKTVNTKRVIQYFATIAALGDKKKESSNSLQ--- 213
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
G LE Q++QANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G +S A+IE
Sbjct: 214 ---------GNLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLSSADIE 264
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRF-LVNRG-ITLPNV 981
YLLEKSRV Q ERS+HIFYQIL E E LL + Y + +++G + + ++
Sbjct: 265 TYLLEKSRVTFQLSAERSYHIFYQILTN-KKPEIVEMLLLTTNPYDYPSISQGELVVKSI 323
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
+D +E +T +++ ++GF +E I ++ AV+ GNL+F Q+++ +QA V K
Sbjct: 324 NDEEELMATDSAIDVLGFNQEEKMGIYKMTGAVMHHGNLKFKQKQREEQAEPDSTEVADK 383
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+ +LLGL +L K PR+KVG EFV K Q Q +V A+ K+ +E+LF W+VTRI
Sbjct: 384 IAYLLGLNSADLLKGLCYPRVKVGNEFVTKGQTVPQVYNSVGALCKSVFEKLFLWMVTRI 443
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 444 NQQLD-TKQPRQFFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 502
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGI+W+FIDFG+DL I+LIEKP+G+ ++L+EEC+FPKA D SF KL + H K
Sbjct: 503 KEGIDWEFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSFKNKLYEQHLGKCKN 562
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P ++++HF++VHYAG VDY+ WL KN DPLNE+VV L Q S+ ++ +
Sbjct: 563 FEKPKPGKGKAEAHFSLVHYAGTVDYNISGWLEKNKDPLNESVVQLYQKSSVKLLSLL-- 620
Query: 1870 DAEFAGICAAEMNETAFGMRSRKG-MFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNH 2046
++ A + + G + +KG F+TVS L +E L KLMT LR+T PHFVRC+IPN
Sbjct: 621 ---YSSYAATDGDAGGKGGKKKKGSSFQTVSGLFRENLNKLMTNLRSTHPHFVRCLIPNE 677
Query: 2047 EKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFID 2223
K G ++++L++ QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L IP+ FID
Sbjct: 678 TKTPGIMDNHLLIHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQFID 737
Query: 2224 GKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLS 2403
K++ K++ ++D+D Y+ G +KVFF+ G+L LEE RD KL LI QA CRG+L
Sbjct: 738 SKKACEKLLGSIDVDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQALCRGYLM 797
Query: 2404 RRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELR 2583
R +T N +++ +++W W +L+ K+KPLL+ T+ E+ +E
Sbjct: 798 RLEFTKMMERREAIYVIQYNLRSFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFE 857
Query: 2584 ATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEY 2763
TKE L+K E +E E+K+ ++ E+ + Q+Q ESE A+ ++ L +LE
Sbjct: 858 KTKEALVKAEARKKELEEKMVAMLQEKNDLVLQVQSESETLADSEERCEGLIKVKIQLES 917
Query: 2764 IVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXX 2943
+ ++ +RL +RK + + +K +
Sbjct: 918 KIKELTERLEDEEESNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 977
Query: 2944 XXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQD 3123
+ L E++ KAK +LE Q+ +LE
Sbjct: 978 LTEEMAVLDENISKLSKEKKALQEAHQQTLDDLQAEEDKVSSLSKAKTKLEQQVDDLEGS 1037
Query: 3124 LNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEE 3303
L +E++ + +LE+ KRKL +L+ +++ + + ++ +L K+D E+ + ++E
Sbjct: 1038 LEQEKKLRLDLERAKRKLEGDLKLTQETVMDLENDKQQTEEKLKKKDFEISQLQGKIEDE 1097
Query: 3304 SANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEA 3483
+ T +QK+++++Q I+E+ E++E ER AR K E R ++ +LE++ + L++ A
Sbjct: 1098 QSLGTQLQKKIKELQARIEEVEEEIEAERAARAKVEKQRADLSRELEEI-SERLEEAGGA 1156
Query: 3484 TMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQ 3660
T Q M++K E E +R +E+ E + K + V EL +QI+ ++ + +
Sbjct: 1157 TSAQIEMNKKREAEFQKLRRDLEEATLQHEATAGALRKKHADSVAELGEQIDNLQRVKQK 1216
Query: 3661 LEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLID- 3837
LEK++++ E D+A + + S+A+++K ++ E L E++ A+ DEH+R L D
Sbjct: 1217 LEKEKSELKMEIDDLASNLENVSKSKANLEKVNRVIEDQLSEVK---AKDDEHQRLLNDL 1273
Query: 3838 --QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRA 4011
Q R + E L+R EE E + + R T+ K A +
Sbjct: 1274 STQKARLQTETGELSRQLEERESLISQLSRGKQGFTQQVEELKRQLEEETKAKNALAHAL 1333
Query: 4012 RQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRD 4191
+ + + L ++ EE + +A L++ + A + R K E Q+ EEL + +
Sbjct: 1334 QSARHDCDLLREQFEEEQEAKAELQRSLSKANGEVSQWRTKYETDAIQRTEELEEAKKKL 1393
Query: 4192 VEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQM 4362
+ LQ E+ E + + ++K+++Q E+ED +++E ++ +K+Q+ F+ +
Sbjct: 1394 AQRLQDAEEQVEAVNSKCASLEKTKQRLQSEVEDLMVDVERANSAAAALDKKQRNFDKVL 1453
Query: 4363 AEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSI 4542
E + ++ + +A +E R T + + N + EH+E R ++LQQE+ D
Sbjct: 1454 VEWKQKYEEGQAELEAALKESRSLSTEIFKMKNAYEEALEHVETLKRENKNLQQEISDLT 1513
Query: 4543 SNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESD 4722
+ GK+V ELEKAK+ +E E ND++ +EE E +L+ E LR+++ +KSE D
Sbjct: 1514 EQIGESGKSVVELEKAKKQVEQEKNDLQAALEEAEGSLEHEEAKILRIQLELNQVKSEVD 1573
Query: 4723 RAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVAN 4902
R I+ KD E E+ +R + I +++ L++E R ++ A+ +KK+E + ELE QL AN
Sbjct: 1574 RKIAEKDEEIEQLKRNSQRSIDTMQSTLDSEIRSRNDALRLKKKMEGDLNELEIQLGHAN 1633
Query: 4903 RLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANE 5082
R E E Q++ +EA +A+ED+ + +R+ +AE E+ R E
Sbjct: 1634 RQASEAQKQLRNVQGQFKETQLQLDEAIRAQEDLKEQVAVTERRNNLFQAEIEENRAGLE 1693
Query: 5083 GLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAID 5253
++RK Q K++LE+ I Q A +
Sbjct: 1694 QTERSRKIAEQELLDASERLQLLHSQNTSLINSKKKLESDICQLQNEAEEAVQEARNAEE 1753
Query: 5254 KQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMA 5433
K +KA + +L E+ + E K++LE++ +D + ++ E E A + Q+
Sbjct: 1754 KAKKAITDAALMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLAMKGGKKQLQ 1813
Query: 5434 ALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNL 5613
LE++V+ LE++L+ E + A + R+ E+R+ + T Q E++K+ + ++L++K
Sbjct: 1814 KLESRVRELENELDNEQKHGVEAVKGVRKYERRVKELTYQTEEDKKNILRLQDLVDKLQS 1873
Query: 5614 KNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
K + +RQ +EAE++ + + R VQ E ++
Sbjct: 1874 KVKAYKRQAEEAEEQANTHLGRFRKVQHELEE 1905
Score = 126 bits (317), Expect = 6e-27
Identities = 140/651 (21%), Positives = 281/651 (42%), Gaps = 38/651 (5%)
Frame = +1
Query: 3028 LTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDH 3207
L+ QL + E + K Q+ EL++ L E + K+ L + + + ++
Sbjct: 1287 LSRQLEERESLISQLSRGKQGFTQQVEELKRQLEEETKAKNALAHALQSARHDCDLLREQ 1346
Query: 3208 LAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTL-MQKQMRDMQTTIDELREDMET 3384
E+ EL L K + E+ T+Y+ ++ T +++ + + + + E +E
Sbjct: 1347 FEEEQEAKAELQRSLSKANGEVSQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEQVEA 1406
Query: 3385 ERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHT 3564
+ E T++ + +++E + DV A L D+ + K+ E+ Q
Sbjct: 1407 VNSKCASLEKTKQRLQSEVEDLMVDVERANSAAAALDKKQRNFDKVLVEWKQKYEEGQAE 1466
Query: 3565 MEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRAD 3744
+E ++E ++ S ++ ++ + E+ + L+++ QE +D+ ++I S +
Sbjct: 1467 LEAALKESRS-LSTEIFKMKNAYEEALEHVETLKRENKNLQQEISDLTEQIGESGKSVVE 1525
Query: 3745 IDKKRKIHEAHLMEIQANLAESD---EHKRTLID----QLERSRDELDHLNRVREEE-EH 3900
++K +K E ++QA L E++ EH+ I +L + + E+D ++EE E
Sbjct: 1526 LEKAKKQVEQEKNDLQAALEEAEGSLEHEEAKILRIQLELNQVKSEVDRKIAEKDEEIEQ 1585
Query: 3901 AFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAH 4080
N QR + T RLK +LE + + EA+ +
Sbjct: 1586 LKRNSQRSIDTMQSTLDSEIRSRNDALRLKKKMEGDLNELEIQLGHANRQASEAQKQLRN 1645
Query: 4081 LEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKK 4260
++ + + EA R E+ Q R+ NL Q ++EE+ E+ +S+K
Sbjct: 1646 VQGQFKETQLQLDEAIRAQEDLKEQVAVTERRNNL-----FQAEIEENRAGLEQTERSRK 1700
Query: 4261 KIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRET 4440
+QEL D+S L+ + + + +KK ES + + + ++A+ QE R+ E
Sbjct: 1701 IAEQELLDASERLQLLHSQNTSLINSKKKLESDICQLQNEAEEAV-------QEARNAEE 1753
Query: 4441 RVLSLLNEVDIMKEHLEES-------DRVRRSLQQELQDSISNKDDFG--------KNVH 4575
+ + + +M E L++ +R++++L+Q ++D D+ K +
Sbjct: 1754 KAKKAITDAALMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLAMKGGKKQLQ 1813
Query: 4576 ELEKAKRSLEAEL-NDMRVQMEEL-----------EDNLQIAEDAR--LRLEVTNQALKS 4713
+LE R LE EL N+ + +E + E Q ED + LRL+ L+S
Sbjct: 1814 KLESRVRELENELDNEQKHGVEAVKGVRKYERRVKELTYQTEEDKKNILRLQDLVDKLQS 1873
Query: 4714 ESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQ 4866
+ +A + EAEE+ L + R +++ELE + A S K+ +
Sbjct: 1874 KV-KAYKRQAEEAEEQANTHLGRFRKVQHELEEAEERADIAESQVNKLRTK 1923
Score = 73.9 bits (180), Expect = 4e-11
Identities = 96/520 (18%), Positives = 206/520 (39%), Gaps = 18/520 (3%)
Frame = +1
Query: 4234 KERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAM 4413
K + L + ++E+ + E E + + +E R+K+ E +M +L +
Sbjct: 835 KIKPLLKSAETEKEMANMKEEFEKTKEALVKAEARKKELEEKMVAMLQEKNDLVLQVQSE 894
Query: 4414 SQELRDRETRVLSLL-------NEVDIMKEHLEESDRV-------RRSLQQELQDSISNK 4551
S+ L D E R L+ +++ + E LE+ + +R L+ E + +
Sbjct: 895 SETLADSEERCEGLIKVKIQLESKIKELTERLEDEEESNAELTAKKRKLEDECSELKKDI 954
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQA----LKSES 4719
DD + ++EK K + E ++ ++ +M L++N+ + L+ +Q L++E
Sbjct: 955 DDLELTLAKVEKEKHATENKVKNLTEEMAVLDENISKLSKEKKALQEAHQQTLDDLQAEE 1014
Query: 4720 DRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
D+ S + + L +Q+ DLE LE EK+ + ++K+E G+L+ E
Sbjct: 1015 DKVSSLSKAKTK-----LEQQVDDLEGSLEQEKKLRLDLERAKRKLE---GDLKLTQETV 1066
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREAN 5079
L+ + + E + + ED +L + +K + ++A E++ E
Sbjct: 1067 MDLEND----KQQTEEKLKKKDFEISQLQGKIEDEQSLGTQLQKKIKELQARIEEVEEEI 1122
Query: 5080 EGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQ 5259
E AR + EK+R + +
Sbjct: 1123 EAERAARAKV--------------------EKQRADLS-------------------REL 1143
Query: 5260 RKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAAL 5439
+ +LE+ S + +N+K EAE Q L R + + + + +A L
Sbjct: 1144 EEISERLEEAGGATSAQIEMNKKREAEFQKLRRDLEEATLQHEATAGALRKKHADSVAEL 1203
Query: 5440 EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKN 5619
++ L+ +EK+ L L + ++ + ++ N ++ L + K+
Sbjct: 1204 GEQIDNLQRVKQKLEKEKSELKMEIDDLASNLENVSKSKANLEKVNRVIEDQLSEVKAKD 1263
Query: 5620 RNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTR 5739
+R L++ + +R +T+ + R+ ++ QL+R
Sbjct: 1264 DEHQRLLNDLSTQKARLQTETGELSRQLEERESLISQLSR 1303
Score = 50.4 bits (119), Expect = 5e-04
Identities = 63/350 (18%), Positives = 132/350 (37%), Gaps = 21/350 (6%)
Frame = +1
Query: 4759 KRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXX 4938
K + LLK + E E+ N K K E + ELE+++ + K +
Sbjct: 835 KIKPLLKSA-ETEKEMANMKEEFEKTKEALVKAEARKKELEEKMVAMLQEKNDLVLQVQS 893
Query: 4939 XXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXX 5118
+ + CE + K + + ++E + E +L
Sbjct: 894 ESETLADSEERCEGLIKVKIQLESKIKELTERLEDEEESNAEL----------------- 936
Query: 5119 XXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTD 5298
+ +KR+LE + ++ + ++ + +++ +T +
Sbjct: 937 ---------------TAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE 981
Query: 5299 LSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNV 5478
+++ K EK++L+ +++ + E S ++A+ LE +V LE L
Sbjct: 982 MAVLDENISKLSKEKKALQEAHQQTLDDLQAEEDKVSSLSKAK-TKLEQQVDDLEGSLEQ 1040
Query: 5479 EGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNL--------------- 5613
E + + RA R+LE L T + D + +Q +E L+K +
Sbjct: 1041 EKKLRLDLERAKRKLEGDLKLTQETVMDLENDKQQTEEKLKKKDFEISQLQGKIEDEQSL 1100
Query: 5614 ------KNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
K + L+ +++E E+E+ ER V+++ DL E+++ L
Sbjct: 1101 GTQLQKKIKELQARIEEVEEEIEAERAARAKVEKQRADLSRELEEISERL 1150
>gi|22121649|gb|AAM88909.1| fast myosin heavy chain HCII [Gallus
gallus]
Length = 1943
Score = 1125 bits (2909), Expect = 0.0
Identities = 658/1897 (34%), Positives = 1062/1897 (55%), Gaps = 23/1897 (1%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V E F+ G+I+ +V V+ + +T+ D V NPPK+DKIEDM+ +T+L
Sbjct: 40 FVAHPKESFVKGTIQSRETGKVTVK-TEGGETLTVKEDQVFSMNPPKYDKIEDMAMMTHL 98
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +V +NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ ++ ++GKKR E PPHIF+
Sbjct: 99 HEPAVPYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVGLAYRGKKRQEAPPHIFS 158
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A + K + +
Sbjct: 159 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAASGEKKKEEQSGKMQ-- 216
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
G LE Q++ ANP+LEAFGN++TV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 217 ---------GTLEDQIISANPLLEAFGNAETVRNDNSSRFGKFIRIHFGATGKLASADIE 267
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPNV 981
YLLEKSRV Q + ERS+HIFYQ+ E E LL + +Y F+ IT+P++
Sbjct: 268 TYLLEKSRVTFQLKAERSYHIFYQVTSN-KKPELIEMLLITTNPYDYPFVSQGEITVPSI 326
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
DD +E +T +++ I+GF DE ++I ++ AV+ GNL+F Q+++ +QA V K
Sbjct: 327 DDKEELMATDSAIDILGFTADEKTAIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADK 386
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L+GL ++ KA PR+KVG E+V K Q +Q AV A+AKA YER+F W+V RI
Sbjct: 387 AAYLMGLNSADMLKALCYPRVKVGNEYVTKGQTVQQVHNAVGALAKAVYERMFLWMVVRI 446
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 447 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H K
Sbjct: 506 KEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSSN 565
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P ++++HF++VHYAG VDY+ WL KN DPLNE V+GL Q S+ +A +
Sbjct: 566 FQKPKPAKGKAEAHFSLVHYAGTVDYNITGWLEKNKDPLNETVIGLYQKSSVKTLALL-- 623
Query: 1870 DAEFAGICAAEMNETAFGMRSRKG------MFRTVSQLHKEQLTKLMTTLRNTSPHFVRC 2031
FA AE + G +KG F+TVS L +E L KLMT LR+T PHFVRC
Sbjct: 624 ---FANYGGAEAEASGGGGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRC 680
Query: 2032 IIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK 2211
IIPN K G + LVL QLRCNGVLEGIRICR+GFP+RV + +F+ RY++L IP+
Sbjct: 681 IIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRVLYADFKQRYKVLNASAIPE 740
Query: 2212 -NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQC 2388
FID K++ K++ ++D+D Y+ G +KVFF+ G+L LEE RD KL +I QA+C
Sbjct: 741 GQFIDSKKASEKLLGSIDVDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQARC 800
Query: 2389 RGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAK 2568
RGFL R Y N A++ +++W W +LF K+KPLL+ ++ E+
Sbjct: 801 RGFLMRVEYQRMVEGRESIFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAESEKEMANM 860
Query: 2569 DDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRN 2748
+E TKE L K E +E E+K+ +++ E+ +Q Q+Q E++ A+ ++ +L
Sbjct: 861 KEEFEKTKEELAKSEAKRKELEEKMVKLVQEKNDLQLQVQAEADALADAEERCDQLIKTK 920
Query: 2749 QELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVD 2928
+LE + ++ +R +RK + + +K +
Sbjct: 921 IQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 980
Query: 2929 QXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLH 3108
+ L E++ KAK +LE Q+
Sbjct: 981 NKVKNLTEEMAALDETIVKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVD 1040
Query: 3109 ELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLT 3288
+LE L +E++ + +LE+ KRKL +L+ S+D + + ++L+ +L K+D E+ +
Sbjct: 1041 DLEGSLEQEKKLRMDLERAKRKLEGDLKMSQDTIMDLENDKQQLDEKLKKKDFEISQIQS 1100
Query: 3289 RYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLD 3468
+ ++E A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L+
Sbjct: 1101 KIEDEQALGMQLQKKIKELQARIEELEEEIEAERTSRAKAEKHRADLSRELEEI-SERLE 1159
Query: 3469 KVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHK 3645
+ AT Q D+ +++ E +R +E+ E + K + EL +QI+ +
Sbjct: 1160 EAGGATAAQIDMNEKREAEFQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQ 1219
Query: 3646 KQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKR 3825
+ + +LEK++++ E D+A + + ++A+++K + E L EI+ ++ +EH+R
Sbjct: 1220 RVKQKLEKEKSELKMEIDDLASNMESVSKAKANLEKMCRTLEDQLSEIK---SKEEEHQR 1276
Query: 3826 TLID---QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIA 3996
+ D Q R + E R ++++ + + R + K A
Sbjct: 1277 MINDLSTQRARLQTESGEYARQADKKDGLISQLSRGKQAFTQQIEELKRQLEEEIKAKNA 1336
Query: 3997 NINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESV---NQQLEE 4167
+ + + + L ++ EE + L++ + A + R K E ++LEE
Sbjct: 1337 LAHSLQSARHDCDLLREQYEEELEAKGELQRALSKANSEVAQWRTKYETDAIQRTEELEE 1396
Query: 4168 LRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKK 4347
+KK + ++ ++ +E E + ++K+++Q E+ED +++E A+ +K+QK
Sbjct: 1397 AKKKLAQRLQDAEEHVEACECQMRFLEKTKQRLQNEVEDLMIDVERANAACAALDKKQKN 1456
Query: 4348 FESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQE 4527
F+ +AE + ++ + +A +E R T + + N + +HLE R ++LQ+E
Sbjct: 1457 FDKILAEWKQKYEETQAELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQRE 1516
Query: 4528 LQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQAL 4707
+ D + GK +HELEK K+ +E E ++++ +EE E +L+ E LRL++ +
Sbjct: 1517 ISDLTEQIAEGGKAIHELEKVKKQIEQEKSEIQAALEEAEASLEHEEGKILRLQLELNQV 1576
Query: 4708 KSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQ 4887
KSE DR I+ KD E ++ +R L+ + L++ L+ E R ++ A+ +KK+E + E+E Q
Sbjct: 1577 KSEIDRKIAEKDEEIDQLKRNHLRIVESLQSSLDAEIRSRNEALRLKKKMEGDLNEMEIQ 1636
Query: 4888 LEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQL 5067
L ANR+ E + QI ++A + +ED+ + +R+ ++AE E+L
Sbjct: 1637 LSHANRVAAEAQKNLRNTQAVLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEIEEL 1696
Query: 5068 REANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNC 5238
R A E ++RK Q K++LE IAQ
Sbjct: 1697 RAALEQTERSRKVAEQELMDASERVQLLHTQNTSLINTKKKLETDIAQIQSEMEDTIQEA 1756
Query: 5239 ELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRA 5418
A +K +KA + +L E+ + E K++L+++ +D + ++ E E A
Sbjct: 1757 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLDQTVKDLQHRLDEAEQLALKGG 1816
Query: 5419 RAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELL 5598
+ Q+ LEA+V+ LE +++ E + A + R+ E+R+ + T E++++ + ++L+
Sbjct: 1817 KKQIQKLEARVRELEGEVDAEQKRSAEAVKGVRKYERRVKELTYLSEEDRKNILRLQDLV 1876
Query: 5599 EKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+K +K ++ +RQ +EAE+ + +K R +Q E ++
Sbjct: 1877 DKLQMKVKSYKRQSEEAEELSNVNLSKFRKIQHELEE 1913
Score = 158 bits (399), Expect = 2e-36
Identities = 187/922 (20%), Positives = 387/922 (41%), Gaps = 36/922 (3%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + + +++L + + ELE+ KL+ E D + + A+ + EE +
Sbjct: 855 KEMANMKEEFEKTKEELAKSEAKRKELEEKMVKLVQEKNDLQLQVQAEADALADAEERCD 914
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE N L K+ R ++ EL++D++ E
Sbjct: 915 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKDIDD-------LE 966
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E L + + + +E A + A +Q ++ +
Sbjct: 967 LTLAKVEKEKHATENKVKNLTEEMAALDETIVKLTKEKKALQEAHQQTLDDLQAEEDKVN 1026
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK 3753
+ + K K +QV++L +EQ KK R LE+ + + + + I L+ + +D+
Sbjct: 1027 TLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKMSQDTIMDLENDKQQLDE 1086
Query: 3754 KRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLAT 3933
K K + + +IQ+ + E ++ L QL++ EL R+ E EE A R
Sbjct: 1087 KLKKKDFEISQIQSKI----EDEQALGMQLQKKIKELQ--ARIEELEEEIEAERTSRAKA 1140
Query: 3934 AXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQG 4113
RL+ A A Q++ ++EK EAE
Sbjct: 1141 EKHRADLSRELEEISERLEEAGGATAAQID------MNEKREAE---------------- 1178
Query: 4114 AGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELED 4284
+ RR EE+ Q LRKK+ L +Q++ + K+++ + K +++ E++D
Sbjct: 1179 FQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDD 1238
Query: 4285 SSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNE 4464
+ +E+V + + EK + E Q++E + + + + D T+ L E
Sbjct: 1239 LASNMESVSKAKANLEKMCRTLEDQLSEIK-------SKEEEHQRMINDLSTQRARLQTE 1291
Query: 4465 VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAK----RSLEAELNDMRVQ 4632
++ D + L + Q ++ + + E KAK SL++ +D +
Sbjct: 1292 SGEYARQADKKDGLISQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHSLQSARHDCDLL 1351
Query: 4633 MEELEDNLQIAEDARLRL-----EVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLE 4797
E+ E+ L+ + + L EV K E+D AI + E EE ++ L ++++D E
Sbjct: 1352 REQYEEELEAKGELQRALSKANSEVAQWRTKYETD-AIQRTE-ELEEAKKKLAQRLQDAE 1409
Query: 4798 NELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECE 4977
+E + +++++N++ +L +E AN E++ + E
Sbjct: 1410 EHVEACECQMRFLEKTKQRLQNEVEDLMIDVERANAACAALDKKQKNFDKILAEWKQKYE 1469
Query: 4978 EARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGG 5157
E + E R + ++ E+ + E L + K A+GG
Sbjct: 1470 ETQAELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQREISDLTEQIAEGGK 1529
Query: 5158 ISSE---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQK 5328
E K+++E + ++ +++ E K + Q++L Q+ ++ +++K
Sbjct: 1530 AIHELEKVKKQIEQEKSEIQAALEEAEASLEHEEGKILRLQLELNQVKSE------IDRK 1583
Query: 5329 TEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANR 5508
+ + +++ R++ + L+S + R++ AL K + +E LN + + ANR
Sbjct: 1584 IAEKDEEIDQLKRNHLRIVESLQSSLDAEIRSRNEALRLK-KKMEGDLNEMEIQLSHANR 1642
Query: 5509 AARRLEKR-------LNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSR 5667
A +K L DT +D R E KE + + L+ +++E + +
Sbjct: 1643 VAAEAQKNLRNTQAVLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEIEELRAALEQ 1702
Query: 5668 ERTKHRNVQREADDLLDANEQL 5733
+ ++E L+DA+E++
Sbjct: 1703 TERSRKVAEQE---LMDASERV 1721
Score = 141 bits (355), Expect = 2e-31
Identities = 177/900 (19%), Positives = 362/900 (39%), Gaps = 122/900 (13%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ +++ ++ +E+D ++ ++KL + E + IQ +++ E +L LQ
Sbjct: 1061 RKLEGDLKMSQDTIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQ 1120
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + +R S R ++E + + +
Sbjct: 1121 ARIEELEEEIE--AERTSRAKAEKHRADLSR--ELEEISERLEEAGGATAAQIDMNEKRE 1176
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K L+
Sbjct: 1177 AEFQKMRRDLEEATLQHEATAAALRKKHADSTAELG---EQIDNLQRVKQKLEKEKSELK 1233
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K+ LE+ R L +L + K E + +L+ Q + E
Sbjct: 1234 MEIDDLASNMESVSKAKANLEKMCRTLEDQLSEIKSKEEEHQRMINDLSTQRARLQTESG 1293
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ D++ ++ + + + I+EL+ +E E A+N + + + ++
Sbjct: 1294 EYARQADKKDGLISQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHSLQSARHDCDLLRE 1353
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
++++ LQ +S+ + EV TK + IQ T E +EE K K ++++++ +
Sbjct: 1354 QYEEELEAKGELQRALSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQDAEEH 1411
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME-------I 3789
+E + Q LEK + + E D+ ++ A+ A +DKK+K + L E
Sbjct: 1412 VEACECQMRFLEKTKQRLQNEVEDLMIDVERANAACAALDKKQKNFDKILAEWKQKYEET 1471
Query: 3790 QANLAESDEHKRTLIDQLERSR----DELDHLNRVREEEEHAFANMQRRLATAXXXXXXX 3957
QA L S + R+L +L + + + LDHL ++ E + N+QR ++
Sbjct: 1472 QAELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENK----NLQREISDLTEQIAEG 1527
Query: 3958 XXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKA 4137
++K +Q+E EK+ + EEAE H E +I + + + +
Sbjct: 1528 GKAIHELEKVK-------KQIEQEKSEIQAALEEAEASLEHEEGKILRLQLELNQVKSEI 1580
Query: 4138 EESV---NQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE-- 4302
+ + ++++++L++ +LR VE LQ L+ ++ L+ KKK++ +L + ++L
Sbjct: 1581 DRKIAEKDEEIDQLKRNHLRIVESLQSSLDAEIRSRNEALRLKKKMEGDLNEMEIQLSHA 1640
Query: 4303 ------------NVRASHRDS---------------------EKRQKKFESQMAEERVAV 4383
N +A +D+ E+R ++++ E R A+
Sbjct: 1641 NRVAAEAQKNLRNTQAVLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEIEELRAAL 1700
Query: 4384 QKALLDRDAMSQELRDRETRV-------LSLLN-----EVDI------MKEHLEESDRVR 4509
++ R QEL D RV SL+N E DI M++ ++E+
Sbjct: 1701 EQTERSRKVAEQELMDASERVQLLHTQNTSLINTKKKLETDIAQIQSEMEDTIQEARNAE 1760
Query: 4510 RSLQQELQDSISNKDDFGKNVH---ELEKAKRSLEAELNDMRVQMEELED------NLQI 4662
++ + D+ ++ K LE+ K++L+ + D++ +++E E QI
Sbjct: 1761 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLDQTVKDLQHRLDEAEQLALKGGKKQI 1820
Query: 4663 AE-DARLR------------------------LEVTNQALKSESDR-------------- 4725
+ +AR+R V SE DR
Sbjct: 1821 QKLEARVRELEGEVDAEQKRSAEAVKGVRKYERRVKELTYLSEEDRKNILRLQDLVDKLQ 1880
Query: 4726 ----AISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLE 4893
+ + EAEE L + R +++ELE + A S K+ + E +++E
Sbjct: 1881 MKVKSYKRQSEEAEELSNVNLSKFRKIQHELEEAEERADIAESQVNKLRAKSREFHRRIE 1940
Score = 137 bits (344), Expect = 4e-30
Identities = 167/900 (18%), Positives = 368/900 (40%), Gaps = 72/900 (8%)
Frame = +1
Query: 3256 KRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVA 3435
K ++ + + EE A +K++ + + + + D++ + A A E
Sbjct: 855 KEMANMKEEFEKTKEELAKSEAKRKELEEKMVKLVQEKNDLQLQVQAEADALADAEERCD 914
Query: 3436 QLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVE 3615
QL K K + K+ E T + +EE+NA ++ +K K +
Sbjct: 915 QLIKTKIQLEAKIKEVTE----RAEDEEEINA--------------ELTAKKRKLEDECS 956
Query: 3616 ELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRK-IHEAHLMEIQ 3792
EL I+ + +++EK+++ + + ++ +E+A L + + K++K + EAH +
Sbjct: 957 ELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAALDETIVKLTKEKKALQEAHQQTLD 1016
Query: 3793 ANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXX 3972
AE D+ TL + ++D L E+E+ +++R
Sbjct: 1017 DLQAEEDK-VNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLER----------------- 1058
Query: 3973 XXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVN 4152
A L+ ++ ++D + + + L L+K+ Q +++ + E+++
Sbjct: 1059 -------AKRKLEGDLKMSQDTIMDLENDKQQLDEKLKKKDFEISQI--QSKIEDEQALG 1109
Query: 4153 QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSE 4332
QL++ K+ +E L++++E ++ + + + + +ELE+ S LE +
Sbjct: 1110 MQLQKKIKELQARIEELEEEIEAERTSRAKAEKHRADLSRELEEISERLEEAGGATAAQI 1169
Query: 4333 KRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNE-VDIMKEHLEESDRVR 4509
+K E++ + R +++A L +A + LR + + L E +D ++ ++ ++ +
Sbjct: 1170 DMNEKREAEFQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEK 1229
Query: 4510 RSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLE 4689
L+ E+ D SN + K LEK R+LE +L++++ + EE + + R RL+
Sbjct: 1230 SELKMEIDDLASNMESVSKAKANLEKMCRTLEDQLSEIKSKEEEHQRMINDLSTQRARLQ 1289
Query: 4690 VTNQALKSESDRAISNKDVEAEEKRRG---LLKQIRDLENELENEKRGKSGAV----SHR 4848
+ ++D+ KD + RG +QI +L+ +LE E + K+ S R
Sbjct: 1290 TESGEYARQADK----KDGLISQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHSLQSAR 1345
Query: 4849 KKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIEC----EEARQAKEDIAALL 5016
+ + E++LE L+ +Y+ + EE +AK+ +A L
Sbjct: 1346 HDCDLLREQYEEELEAKGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1405
Query: 5017 READRKFRAVEAE-------REQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEK 5175
++A+ A E + +++L+ E LM ++ + I +E K
Sbjct: 1406 QDAEEHVEACECQMRFLEKTKQRLQNEVEDLMIDVERANAACAALDKKQKNFDKILAEWK 1465
Query: 5176 RRLEAKIAQXXXXXXXXQS-----------------NCELAIDKQRKAQVQLEQITTDLS 5304
++ E A+ +S + E + + Q ++ +T ++
Sbjct: 1466 QKYEETQAELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQREISDLTEQIA 1525
Query: 5305 MERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRA----RAQMAALEAK-------- 5448
+ E K+ +E+ + +A + E E+ + R Q+ + K
Sbjct: 1526 EGGKAIHELEKVKKQIEQEKSEIQAALEEAEASLEHEEGKILRLQLELNQVKSEIDRKIA 1585
Query: 5449 ----------------VQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANE 5580
V+ L+ L+ E + + A R +++E LN+ Q R
Sbjct: 1586 EKDEEIDQLKRNHLRIVESLQSSLDAEIRSRNEALRLKKKMEGDLNEMEIQLSHANRVAA 1645
Query: 5581 QAKELLEKSNLKNRNLRRQLDEA-------EDEMSRERTKHRNVQREADDLLDANEQLTR 5739
+A++ L + ++ + LD+A +++++ + +Q E ++L A EQ R
Sbjct: 1646 EAQKNLRNTQAVLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEIEELRAALEQTER 1705
Score = 52.0 bits (123), Expect = 2e-04
Identities = 66/328 (20%), Positives = 135/328 (41%), Gaps = 30/328 (9%)
Frame = +1
Query: 4852 KIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADR 5031
KI+ + E + E+AN +KEE+ + ++ +E + L++E +
Sbjct: 843 KIKPLLKSAESEKEMAN-MKEEFEKTKEELAKSEAK-------RKELEEKMVKLVQEKND 894
Query: 5032 KFRAVEAEREQLREANEG---LMQARKQXXXXXXXXXXXRAKGGGISSE---EKRRLEAK 5193
V+AE + L +A E L++ + Q I++E +KR+LE +
Sbjct: 895 LQLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE 954
Query: 5194 IAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDY 5373
++ + ++ + +++ +T +++ K EK++L+ +++
Sbjct: 955 CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAALDETIVKLTKEKKALQEAHQQT 1014
Query: 5374 KAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLE---KRLNDT 5544
+ E + +A+ LE +V LE L E + + RA R+LE K DT
Sbjct: 1015 LDDLQAEEDKVNTLTKAK-TKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKMSQDT 1073
Query: 5545 TQQFEDEKRANEQAKELLEKSNL---------------------KNRNLRRQLDEAEDEM 5661
E++K +Q E L+K + K + L+ +++E E+E+
Sbjct: 1074 IMDLENDK---QQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQARIEELEEEI 1130
Query: 5662 SRERTKHRNVQREADDLLDANEQLTREL 5745
ERT ++ DL E+++ L
Sbjct: 1131 EAERTSRAKAEKHRADLSRELEEISERL 1158
>gi|24584700|ref|NP_724003.1| CG17927-PF [Drosophila melanogaster]
gi|22946663|gb|AAN10962.1| CG17927-PF [Drosophila melanogaster]
Length = 1962
Score = 1124 bits (2907), Expect = 0.0
Identities = 679/1916 (35%), Positives = 1083/1916 (56%), Gaps = 31/1916 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K CW+PD+ EG+L+G IK D V V L + + +D +Q+ NPPK++K EDMS
Sbjct: 35 KKSCWIPDEKEGYLLGEIKATKGDIVSVGLQGGETR-DLKKDLLQQVNPPKYEKAEDMSN 93
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LTYLN+ASVLHNL+ RYY+ LIYTYSGLFCV INPYK+ P+Y+ + ++GK+R+E+PP
Sbjct: 94 LTYLNDASVLHNLRQRYYNKLIYTYSGLFCVAINPYKRYPVYTNRCAKMYRGKRRNEVPP 153
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIFAI+D AY ML +QS+L TGESGAGKTENTKKVI Y A V +K + AA+
Sbjct: 154 HIFAISDGAYVDMLTNHVNQSMLITGESGAGKTENTKKVIAYFATVGA---SKKTDEAAK 210
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
G LE Q++Q NP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++G
Sbjct: 211 SK-----------GSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFGPTGKLAG 259
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLL-EGVDNYRFLVNRGITL 972
A+IE YLLEK+RV+ Q ERS+HIFYQI+ G K LL + + +Y + +T+
Sbjct: 260 ADIETYLLEKARVISQQSLERSYHIFYQIMSGSVPGVKDICLLTDNIYDYHIVSQGKVTV 319
Query: 973 PNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRV 1152
++DD +EF T + I+GF E + R+ +AV+ +G ++F Q + +QA +
Sbjct: 320 ASIDDAEEFSLTDQAFDILGFTKQEKEDVYRITAAVMHMGGMKFKQRGREEQAEQDGEEE 379
Query: 1153 IQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLV 1332
+V L G EL K L+PRIKVG EFV + +N +Q ++ A+ K ++RLFKWLV
Sbjct: 380 GGRVSKLFGCDTAELYKNLLKPRIKVGNEFVTQGRNVQQVTNSIGALCKGVFDRLFKWLV 439
Query: 1333 TRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQE 1512
+ N++LD T ++ FIG+LDIAGFEIF+ N FEQ+CIN+TNEKLQQ FN+ MF+LEQE
Sbjct: 440 KKCNETLD-TQQKRQHFIGVLDIAGFEIFEYNGFEQLCINFTNEKLQQFFNHHMFVLEQE 498
Query: 1513 EYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NK 1689
EY+REGI+W FIDFG+DL IDLIEKPMG+L++L+EE +FPKA D++F EKL TH K
Sbjct: 499 EYKREGIDWAFIDFGMDLLACIDLIEKPMGILSILEEESMFPKATDQTFSEKLTNTHLGK 558
Query: 1690 HPKFIVPDM----RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVA 1857
F P + +HFA+ HYAG V Y+ WL KN DPLN+ VV + S + +
Sbjct: 559 SAPFQKPKPPKPGQQAAHFAIAHYAGCVSYNITGWLEKNKDPLNDTVVDQFKKSQNKLLI 618
Query: 1858 GIWKDAEFAGICAAEMNETAFGMRSRK-GMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCI 2034
I+ A+ AG E A G R +K G F TVS +KEQL LMTTLR+T PHFVRCI
Sbjct: 619 EIF--ADHAGQSGG--GEQAKGGRGKKGGGFATVSSAYKEQLNSLMTTLRSTQPHFVRCI 674
Query: 2035 IPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKN 2214
IPN K+ G ++++LV+ QL CNGVLEGIRICR+GFPNR+ + +F+ RY+IL P I K+
Sbjct: 675 IPNEMKQPGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKMRYQILNPRGI-KD 733
Query: 2215 FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRG 2394
K++ + +I + +++ +LYR+G +KVFFR GVL +EE RD +L ++ QA RG
Sbjct: 734 LDCPKKASKVLIESTELNEDLYRLGHTKVFFRAGVLGQMEEFRDERLGKIMSWMQAWARG 793
Query: 2395 FLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDD 2574
+LSR+ + N YL+LR W W++L+ KVKPLL V+R +DEI A+ +
Sbjct: 794 YLSRKGFKKLQEQRVALKVVQRNLRKYLQLRTWPWYKLWQKVKPLLNVSRIEDEI-ARLE 852
Query: 2575 ELRATKERLLKMEHDFRENEKKLD-QVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQ 2751
E E L E R+ + L+ +++ E+ + + L E + + +L +
Sbjct: 853 EKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQDYQERNAKLTAQKN 912
Query: 2752 ELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQ 2931
+LE + D+++RL+ ++K + + DK D
Sbjct: 913 DLENQLRDIQERLTQEEDARNQLFQQKKKADQEISGLKKDIEDLELNVQKAEQDKATKDH 972
Query: 2932 XXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHE 3111
+ + +L E++ H K K +LE L E
Sbjct: 973 QIRNLNDEIAHQDELINKLNKEKKMQGETNQKTGEELQAAEDKINHLNKVKAKLEQTLDE 1032
Query: 3112 LEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTR 3291
LE L RE++ + ++E+ KRK+ +L+ +++ +A+ +EL + ++D+EL +
Sbjct: 1033 LEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVADLERNKKELEQTIQRKDKELSSITAK 1092
Query: 3292 YDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDK 3471
++E V Q+Q++++Q I+EL E++E ER AR KAE R ++ +LE++ G+ L++
Sbjct: 1093 LEDEQVVVLKHQRQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEEL-GERLEE 1151
Query: 3472 VDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKK 3648
AT Q +L +++ E++ +R +E+ E + + K + V E+ +Q++Q K
Sbjct: 1152 AGGATSAQIELNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNK 1211
Query: 3649 QRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRT 3828
+++ EK++N+ + D+ + + +A +K K + L E+Q+ L DE RT
Sbjct: 1212 LKAKAEKEKNEYYGQLNDLRAGVDHITNEKAAQEKIAKQLQHTLNEVQSKL---DETNRT 1268
Query: 3829 LIDQLERSRDEL----DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIA 3996
L D + S+ +L L R EE E + + + + +R +
Sbjct: 1269 LND-FDASKKKLSIENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERAT 1327
Query: 3997 NINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHAARQGAGEARRKAEE---SVNQQLE 4164
+ + R LE + + L ++ +EEAEG +A L++++ A A R K E + +++LE
Sbjct: 1328 LLGKFRNLEHDLDNLREQVEEEAEG-KADLQRQLSKANAEAQVWRSKYESDGVARSEELE 1386
Query: 4165 ELRKKNLRDVEHLQKQLEESEVAKERILQ-------SKKKIQQELEDSSMELENVRASHR 4323
E ++K LQ +L E+E E + Q +K+++ E+ED +E++ A
Sbjct: 1387 EAKRK-------LQARLAEAEETIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIAN 1439
Query: 4324 DSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDR 4503
+EK+QK F+ + E ++ V + DA +E R+ T + L + +E LE R
Sbjct: 1440 AAEKKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRR 1499
Query: 4504 VRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLR 4683
++L E++D + + G+N+HE+EKA++ LEAE ++++ +EE E L+ E+ LR
Sbjct: 1500 ENKNLADEVKDLLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLR 1559
Query: 4684 LEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIEN 4863
++ ++ E DR I K+ E E R+ + + ++ LE E +GK+ A+ +KK+E
Sbjct: 1560 AQLELSQVRQEIDRRIQEKEEEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEA 1619
Query: 4864 QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRA 5043
I ELE L+ AN+ E + Q EE ++A++D L ++R+ A
Sbjct: 1620 DINELEIALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANA 1679
Query: 5044 VEAEREQ----LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXX 5211
++ E E+ L +A+ G QA ++ A+ IS+ KR+LE+++
Sbjct: 1680 LQNELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISA-AKRKLESELQTLHS 1738
Query: 5212 XXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITE 5391
+ + + +K +KA V ++ +L E+ Q E +++LE+ ++ + ++ E
Sbjct: 1739 DLDELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDE 1798
Query: 5392 LESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKR 5571
E+ A + + LE +V+ LE++L+ E + A + R+ E+R+ + + Q E++++
Sbjct: 1799 AEANALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRK 1858
Query: 5572 ANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQR---EADDLLDANEQ 5730
+E+ ++L++K K + +RQ++EAE+ + K R Q+ EA++ D EQ
Sbjct: 1859 NHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQ 1914
Score = 155 bits (391), Expect = 1e-35
Identities = 179/950 (18%), Positives = 386/950 (39%), Gaps = 62/950 (6%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDE 3267
RLE + + E+ E + + ELE KLLAE D L+ + G +++
Sbjct: 850 RLEEKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQD---------- 899
Query: 3268 ELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEK 3447
Y E +A +T Q D++ + +++E + E +ARN+ +++ ++
Sbjct: 900 --------YQERNAKLTA---QKNDLENQLRDIQERLTQEEDARNQLFQQKKKADQEISG 948
Query: 3448 VKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+K D+ D + + KD ++ I Q + K+ ++K ++ +
Sbjct: 949 LKKDIEDLELNVQKAEQDKATKDHQIRNLNDEIAH-QDELINKLNKEKKMQGETNQKTGE 1007
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAE 3807
+++ + + + L K + + +Q ++ + + R D++K ++ E L Q +A+
Sbjct: 1008 ELQAAEDKINHLNKVKAKLEQTLDELEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVAD 1067
Query: 3808 SDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL 3987
+ +K+ L ++R EL + E+E+ QR++
Sbjct: 1068 LERNKKELEQTIQRKDKELSSITAKLEDEQVVVLKHQRQIKELQA--------------- 1112
Query: 3988 KIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEE 4167
R +LE+E A + +AE RA L +E+ + GE +A + + Q+E
Sbjct: 1113 ------RIEELEEEVEAERQARAKAEKQRADLAREL----EELGERLEEAGGATSAQIE- 1161
Query: 4168 LRKKNLRDVEHLQKQLEESEVAKERILQS-KKKIQQELEDSSMELENVRASHRDSEKRQK 4344
L KK ++ L++ LEE+ + E L + +KK + + + +++ + +EK +
Sbjct: 1162 LNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNKLKAKAEKEKN 1221
Query: 4345 KFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQ 4524
++ Q+ + R V ++ A + + + + + +++D L + D ++ L
Sbjct: 1222 EYYGQLNDLRAGVDHITNEKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSI 1281
Query: 4525 ELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE--------------LE---DN 4653
E D + ++ V +L K K SL +L D + +E LE DN
Sbjct: 1282 ENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERATLLGKFRNLEHDLDN 1341
Query: 4654 L--QIAEDARLRLEVTNQALKSESDRAISNKDVEA---------EEKRRGLLKQIRDLEN 4800
L Q+ E+A + ++ Q K+ ++ + E+ EE +R L ++ + E
Sbjct: 1342 LREQVEEEAEGKADLQRQLSKANAEAQVWRSKYESDGVARSEELEEAKRKLQARLAEAEE 1401
Query: 4801 ELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEE 4980
+E+ + G ++++ ++ +L+ +++ AN + E++++ ++
Sbjct: 1402 TIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIANAAEKKQKAFDKIIGEWKLKVDD 1461
Query: 4981 ARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGG-G 5157
+ R + ++ E+ +E E + + K +GG
Sbjct: 1462 LAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGRN 1521
Query: 5158 ISSEEK--RRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKT 5331
I EK +RLEA+ + ++ E +K +AQ++L Q+ ++ +R + +K
Sbjct: 1522 IHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEI--DRRIQEKE 1579
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRARA--QMAALEAKVQYLEDQLNVEGQEKTAAN 5505
E + + + R + LE+ A+ +A A LEA + LE L+ + A
Sbjct: 1580 EEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQ 1639
Query: 5506 RAARRLEKRLNDTTQQFEDEKR----------------------------ANEQAKELLE 5601
+ +R +++L D E+E+R EQA
Sbjct: 1640 KNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRR 1699
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
++ + + QL+E + + R ++ E L ++L E N
Sbjct: 1700 QAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDELLNEAKN 1749
Score = 82.4 bits (202), Expect = 1e-13
Identities = 82/418 (19%), Positives = 183/418 (43%), Gaps = 25/418 (5%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L +Q+ E ++++ + + LE K +L A LE+++ L ++ KV +L + +E
Sbjct: 1511 LLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQE 1570
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ ++ +EE N ++ Q +D ++ +E E + +A ++++ A + ++
Sbjct: 1571 IDRRIQEKEEEFENTR------KNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINEL 1624
Query: 3451 KGDVLDKVDEATM-LQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+ LD ++A Q + R +++ + A+E+ Q + EQ R+ L +
Sbjct: 1625 E-IALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDA-REQLGISERRANALQN 1682
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL-- 3801
++E+ + Q ++ + QA+QE AD +++ + A A I ++ E+ L + ++L
Sbjct: 1683 ELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDE 1742
Query: 3802 ----AESDEHKRT--------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
A++ E K L D+L +D ++R+ E +Q RL A
Sbjct: 1743 LLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAEAN 1802
Query: 3946 XXXXXXXXXXXTRLKIANIN------RARQLEDEKNALLDEKEEAE-GLRAHLEKEIHAA 4104
++ + + R + +KN E+ E ++ +++ H
Sbjct: 1803 ALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRKNHER 1862
Query: 4105 RQGAGEARRKAEESVNQQLEELRK---KNLRDVEHLQKQLEESEVAKERILQSKKKIQ 4269
Q + ++ ++ +Q+EE + NL Q++LEE+E + Q+ K +
Sbjct: 1863 MQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQAISKFR 1920
>gi|5360746|dbj|BAA82144.1| myosin heavy chain 2a [Sus scrofa]
Length = 1939
Score = 1123 bits (2905), Expect = 0.0
Identities = 655/1888 (34%), Positives = 1055/1888 (55%), Gaps = 14/1888 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V + E F+ G+I+ +V V+ + +T+ D V NPPKFDKIEDM+ +T+L
Sbjct: 39 FVAEPKESFVKGTIQSREGGKVTVK-TEAGATLTVKEDQVFPMNPPKFDKIEDMAMMTHL 97
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 98 HEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFS 157
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A K
Sbjct: 158 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKK---------- 207
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
++P G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 208 EEPTSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIE 267
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPNV 981
YLLEKSRV Q + ERS+HIFYQI E E LL + +Y F+ I++ ++
Sbjct: 268 TYLLEKSRVTFQLKAERSYHIFYQITSN-RKPELIEMLLITTNPYDYPFISQGEISVASI 326
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
DD +E +T +++ I+GF ++E SI ++ AV+ GNL+F Q+++ +QA V K
Sbjct: 327 DDQEELIATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADK 386
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L L +L KA PR+KVG E+V K Q EQ AV A+AKA YE++F W+VTRI
Sbjct: 387 AAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVTNAVGALAKAVYEKMFLWMVTRI 446
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 447 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
REGIEW FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL + H K
Sbjct: 506 REGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSAN 565
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P + ++HF+++HYAG VDY+ WL KN DPLN+ VVGL Q S +A ++
Sbjct: 566 FQKPKPAKGKVEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSALKTLAFLFS 625
Query: 1870 DAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHE 2049
A+ AE T G + + F+TVS L +E L KLMT LR+T PHFVRCIIPN
Sbjct: 626 GAQTG---EAEAGGTKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 682
Query: 2050 KKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDG 2226
K G + LVL QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L IP+ +ID
Sbjct: 683 KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQYIDS 742
Query: 2227 KESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSR 2406
K++ K++ ++DID Y+ G +KVFF+ G+L LEE RD KL LI QA+CRGFL+R
Sbjct: 743 KKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLAR 802
Query: 2407 RLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRA 2586
Y N A++ +++W W +LF K+KPLL+ ++ E+ +E +
Sbjct: 803 VEYQKMVERRESIFCIQYNIRAFMNVKHWPWMKLFFKIKPLLKSAESEKEMATMKEEFQK 862
Query: 2587 TKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYI 2766
TK+ L K E +E E+K+ ++ E+ +Q Q+Q E+E A+ ++ +L +LE
Sbjct: 863 TKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAK 922
Query: 2767 VNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXX 2946
+ ++ +R +RK + + +K +
Sbjct: 923 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 982
Query: 2947 XXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDL 3126
+ L E++ KAK +LE Q+ +LE L
Sbjct: 983 TEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSL 1042
Query: 3127 NRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEES 3306
+E++ + +LE+ KRKL +L+ +++ + + + ++L+ +L K++ E+ + ++ ++E
Sbjct: 1043 EQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQ 1102
Query: 3307 ANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT 3486
A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L++ AT
Sbjct: 1103 ALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEI-SERLEEAGGAT 1161
Query: 3487 MLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQL 3663
Q M++K E E +R +E+ E + K + V EL +QI+ ++ + +L
Sbjct: 1162 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKL 1221
Query: 3664 EKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQL 3843
EK++++ E D+A + + ++ +++K + E L E+++ E L Q
Sbjct: 1222 EKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQR 1281
Query: 3844 ERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLE 4023
R + E +R +E+E + + R + K A + +
Sbjct: 1282 GRLQTESGEFSRQLDEKEALVSQLSRGKQAYTQQIEELKRQLEEEIKAKNALAHALQSSR 1341
Query: 4024 DEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHL 4203
+ + L ++ EE + +A L++ + A + R K E Q+ EEL + + + L
Sbjct: 1342 HDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1401
Query: 4204 QKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEER 4374
Q E E + + ++K+++Q E+ED +++E A+ +K+Q+ F+ +AE +
Sbjct: 1402 QAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWK 1461
Query: 4375 VAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKD 4554
++ + +A +E R T + + N + + LE R ++LQQE+ D
Sbjct: 1462 QKYEETHAELEASQKEARSLGTELFKMKNAYEESLDQLETLKRENKNLQQEISDLTEQIA 1521
Query: 4555 DFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAIS 4734
+ GK +HELEK K+ +E E ++++ +EE E +L+ E LR+++ +KSE DR I+
Sbjct: 1522 EGGKRIHELEKIKKQVEQEKSEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIA 1581
Query: 4735 NKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKE 4914
KD E ++ +R ++ + +++ L+ E R ++ A+ +KK+E + E+E QL ANR+
Sbjct: 1582 EKDEEIDQLKRNHVRVVESMQSMLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAA 1641
Query: 4915 EYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQ 5094
E + QI ++A + +ED+ L +R+ ++AE E+LR E +
Sbjct: 1642 EALRNYRNTQGILKDTQIHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1701
Query: 5095 ARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRK 5265
+RK Q K++LE I+Q A +K +K
Sbjct: 1702 SRKVAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKK 1761
Query: 5266 AQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEA 5445
A + +L E+ + E K+++E++ +D + ++ E E A + Q+ LEA
Sbjct: 1762 AITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQKLEA 1821
Query: 5446 KVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRN 5625
+V+ LE ++ E + A + R+ E+R+ + T Q E++++ + ++L++K K ++
Sbjct: 1822 RVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKS 1881
Query: 5626 LRRQLDEAEDEMSRERTKHRNVQREADD 5709
+RQ +EAE++ + +K R +Q E ++
Sbjct: 1882 YKRQAEEAEEQSNTNLSKFRKLQHELEE 1909
Score = 153 bits (387), Expect = 4e-35
Identities = 189/937 (20%), Positives = 391/937 (41%), Gaps = 51/937 (5%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + + + +L + + ELE+ LL E D + + AE + EE +
Sbjct: 851 KEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCD 910
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE N L K+ R ++ EL++D++ E
Sbjct: 911 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKDIDD-------LE 962
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E L + +++ +E A + A +Q ++ +
Sbjct: 963 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1022
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK 3753
+ + K K +QV++L +EQ KK R LE+ + + + + + I ++ + +D+
Sbjct: 1023 TLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDE 1082
Query: 3754 KRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLAT 3933
K K E + +Q+ + E ++ L QL++ EL R+ E EE A R
Sbjct: 1083 KLKKKEFEISNLQSKI----EDEQALAIQLQKKIKELQ--ARIEELEEEIEAERASRAKA 1136
Query: 3934 AXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQG 4113
RL+ A + Q+E +++K EAE
Sbjct: 1137 EKQRSDLSRELEEISERLEEAGGATSAQIE------MNKKREAE---------------- 1174
Query: 4114 AGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELED 4284
+ RR EE+ Q LRKK+ V L +Q++ + K+++ + K +++ E++D
Sbjct: 1175 FQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDD 1234
Query: 4285 SSMELENVRASHRDSEKRQKKFESQMAEER------------VAVQKALLDRDA--MSQE 4422
+ +E V + + EK + E Q++E + + Q+ L ++ S++
Sbjct: 1235 LASNMETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQ 1294
Query: 4423 LRDRETRVLSL-------LNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHEL 4581
L ++E V L +++ +K LEE + + +L LQ S + D + E
Sbjct: 1295 LDEKEALVSQLSRGKQAYTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEE 1354
Query: 4582 EKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEK 4761
+++K L+ L ++ EV K E+D AI + E EE
Sbjct: 1355 QESKAELQRAL-------------------SKANTEVAQWRTKYETD-AIQRTE-ELEEA 1393
Query: 4762 RRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVAN----RLKEEYXXX 4929
++ L ++++ E +E + +++++N++ +L +E N L ++
Sbjct: 1394 KKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNF 1453
Query: 4930 XXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQX 5109
+Y+ E ++++ +L E + A E +QL E L + K
Sbjct: 1454 DKILAEWKQKYEETHAELEASQKEARSLGTELFKMKNAYEESLDQL----ETLKRENKNL 1509
Query: 5110 XXXXXXXXXXRAKGGGISSE---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQL 5280
A+GG E K+++E + ++ +++ E K + Q++L
Sbjct: 1510 QQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSEIQAALEEAEASLEHEEGKILRIQLEL 1569
Query: 5281 EQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAA------LE 5442
Q+ ++ +++K + + +++ R++ + ++S + R++ A +E
Sbjct: 1570 NQVKSE------VDRKIAEKDEEIDQLKRNHVRVVESMQSMLDAEIRSRNDAIRLKKKME 1623
Query: 5443 AKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNR 5622
+ +E QLN + A R R + L DT +D R E KE L +
Sbjct: 1624 GDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRGQEDLKEQLAMVERRAN 1683
Query: 5623 NLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQL 5733
L+ +++E + + + ++E LLDA+E++
Sbjct: 1684 LLQAEIEELRATLEQTERSRKVAEQE---LLDASERV 1717
Score = 124 bits (311), Expect = 3e-26
Identities = 134/756 (17%), Positives = 312/756 (40%), Gaps = 45/756 (5%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + ++ D++ + + +R +LE++ +E+ D+ ++ AD ++
Sbjct: 850 EKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERC 909
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ + +E L + + DE L + ++ E A ++
Sbjct: 910 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 969
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ K A N+ + L +E L +E +K +
Sbjct: 970 KE---------------------KHATENKVKNLTEEMAGL----DETIAKLTKEKKALQ 1004
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
A Q + + E+ VN L + + K + V+ L+ LE+ + + + ++K+K++ +L
Sbjct: 1005 EAHQQTLDDLQAEEDKVNT-LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDL 1063
Query: 4279 ---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL 4449
++S M++EN + D + ++K+FE + ++ ++AL + + +++++ + R+
Sbjct: 1064 KLAQESIMDIENEK-QQLDEKLKKKEFEISNLQSKIEDEQALAIQ--LQKKIKELQARIE 1120
Query: 4450 SLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRV 4629
L E++ + ++++ R L +EL++ ++ G + + EAE MR
Sbjct: 1121 ELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR 1180
Query: 4630 QME----------------------ELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
+E EL + + + + +LE +K E D SN +
Sbjct: 1181 DLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNME 1240
Query: 4744 VEAEEKR------RGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANR 4905
++ K R L Q+ +L+++ E ++R + + R +++ + GE +QL+
Sbjct: 1241 TVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEA 1300
Query: 4906 LKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLR----EADRKFRAVEAEREQLRE 5073
L + E + + EE +AK +A L+ + D E E+E E
Sbjct: 1301 LVSQLSRGKQAYTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAE 1360
Query: 5074 ANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAID 5253
L +A + + E K++L ++ + C
Sbjct: 1361 LQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEK 1420
Query: 5254 KQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES---GAQSRARA 5424
+++ Q ++E + D+ + ++++ ++ ++K K E + +Q AR+
Sbjct: 1421 TKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKYEETHAELEASQKEARS 1480
Query: 5425 QMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEK 5604
L E+ L+ + R + L++ ++D T+Q + + + +++ ++
Sbjct: 1481 LGTELFKMKNAYEESLD----QLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQ 1536
Query: 5605 SNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ ++ L+EAE + E K +Q E + +
Sbjct: 1537 VEQEKSEIQAALEEAEASLEHEEGKILRIQLELNQV 1572
Score = 114 bits (285), Expect = 3e-23
Identities = 173/890 (19%), Positives = 357/890 (39%), Gaps = 113/890 (12%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ +E ++ +E++ ++ ++KL + E + +Q +++ E + +L LQ
Sbjct: 1057 RKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALAIQLQKKIKELQ 1116
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + +R S R ++E + + +
Sbjct: 1117 ARIEELEEEIE--AERASRAKAEKQRSDLSR--ELEEISERLEEAGGATSAQIEMNKKRE 1172
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K ++
Sbjct: 1173 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELG---EQIDNLQRVKQKLEKEKSEMK 1229
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K LE+ R L +L + K E+ + +L Q + E
Sbjct: 1230 MEIDDLASNMETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESG 1289
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ DE+ A V+ + + + I+EL+ +E E A+N + + ++
Sbjct: 1290 EFSRQLDEKEALVSQLSRGKQAYTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLRE 1349
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
++ + LQ +S+ + EV TK + IQ T E +EE K K +++++ +
Sbjct: 1350 QYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQAAEEH 1407
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME-------I 3789
+E + + LEK + + E D+ ++ A+ A +DKK++ + L E
Sbjct: 1408 VEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKYEET 1467
Query: 3790 QANLAESDEHKRTLIDQL-------ERSRDELDHLNRVREEEEHAFANMQRRLAT----- 3933
A L S + R+L +L E S D+L+ L R + + +++ ++A
Sbjct: 1468 HAELEASQKEARSLGTELFKMKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRI 1527
Query: 3934 ------------------AXXXXXXXXXXXXXXTRLKIA-NINRARQLEDEKNALLDEKE 4056
A L+I +N+ + D K A DE+
Sbjct: 1528 HELEKIKKQVEQEKSEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEI 1587
Query: 4057 E---------AEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN------LRD 4191
+ E +++ L+ EI + R A ++K E +N+ +L N LR+
Sbjct: 1588 DQLKRNHVRVVESMQSMLDAEIRS-RNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRN 1646
Query: 4192 VEHLQKQLEESEVAKERILQSKKKIQQELEDSSM-------ELENVRASHRDSEKRQKKF 4350
+ Q L+++++ + L+ ++ ++++L E+E +RA+ +E+ +K
Sbjct: 1647 YRNTQGILKDTQIHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKVA 1706
Query: 4351 ESQM--AEERVAV----------QKALLDRDAMS---------QELRDRETRVLSLLNEV 4467
E ++ A ERV + K L+ D QE R+ E + + +
Sbjct: 1707 EQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDA 1766
Query: 4468 DIMKEHLEES-------DRVRRSLQQELQDSISNKDDFG--------KNVHELEKAKRSL 4602
+M E L++ +R++++++Q ++D D+ K + +LE R L
Sbjct: 1767 AMMAEELKKEQDTSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVREL 1826
Query: 4603 EAELNDMRVQMEELEDNL------------QIAEDAR--LRLEVTNQALKSESDRAISNK 4740
E E+ + + E L Q ED + LRL+ L+++ ++ +
Sbjct: 1827 EGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKV-KSYKRQ 1885
Query: 4741 DVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
EAEE+ L + R L++ELE + A S K+ + E+ ++
Sbjct: 1886 AEEAEEQSNTNLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKV 1935
Score = 70.1 bits (170), Expect = 6e-10
Identities = 105/521 (20%), Positives = 199/521 (38%), Gaps = 18/521 (3%)
Frame = +1
Query: 4234 KERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAM 4413
K + L + ++E+ E + + SE ++K+ E +M L A
Sbjct: 839 KIKPLLKSAESEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 898
Query: 4414 SQELRDRETRVLSLLN-------EVDIMKEHLEESDRV-------RRSLQQELQDSISNK 4551
++ L D E R L+ ++ + E E+ + + +R L+ E + +
Sbjct: 899 AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 958
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQA----LKSES 4719
DD + ++EK K + E ++ ++ +M L++ + + L+ +Q L++E
Sbjct: 959 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1018
Query: 4720 DRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
D+ N +A+ K L +Q+ DLE LE EK+ + ++K+E + ++ +
Sbjct: 1019 DKV--NTLTKAKTK---LEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDI 1073
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREAN 5079
K++ + + E + ED AL + +K + ++A E+L E
Sbjct: 1074 ENEKQQLDEKLK-------KKEFEISNLQSKIEDEQALAIQLQKKIKELQARIEELEEEI 1126
Query: 5080 EGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQ 5259
E RAK S+ R LE
Sbjct: 1127 EA--------------ERASRAKAEKQRSDLSRELE------------------------ 1148
Query: 5260 RKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAAL 5439
+ +LE+ S + +N+K EAE Q + R +LE A + A AAL
Sbjct: 1149 -EISERLEEAGGATSAQIEMNKKREAEFQKMRR----------DLEE-ATLQHEATAAAL 1196
Query: 5440 EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKN 5619
K D + G++ R ++LEK ++ + +D +E +
Sbjct: 1197 RKK---HADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDD-------LASNMETVSKAK 1246
Query: 5620 RNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
NL + ED++S ++K QR +DL +L E
Sbjct: 1247 GNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTE 1287
>gi|5360748|dbj|BAA82145.1| myosin heavy chain 2b [Sus scrofa]
Length = 1937
Score = 1123 bits (2905), Expect = 0.0
Identities = 653/1891 (34%), Positives = 1063/1891 (55%), Gaps = 17/1891 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V + E F+ G+++ +V V+ + +T+ D V NPPKFDKIEDM+ +T+L
Sbjct: 39 FVAEPKESFVKGTVQSREGGKVTVK-TEAGATLTVKEDQVFPMNPPKFDKIEDMAMMTHL 97
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 98 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFS 157
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A K
Sbjct: 158 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKK---------- 207
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
++P G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 208 EEPTPGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIE 267
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPNV 981
YLLEKSRV Q + ERS+HIFYQI+ E E LL + +Y F+ IT+P++
Sbjct: 268 TYLLEKSRVTFQLKAERSYHIFYQIMSN-KKPELIEMLLITTNPYDYAFVSQGEITVPSI 326
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
DD +E +T +++ I+GF DE SI ++ AV+ GNL+F Q+++ +QA V K
Sbjct: 327 DDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADK 386
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L GL +L KA PR+KVG EFV K Q +Q AV A+AKA Y+++F W+VTRI
Sbjct: 387 AAYLQGLNSADLLKALCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTRI 446
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 447 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL + H K
Sbjct: 506 KEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNN 565
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P ++++HF+++HYAG VDY+ WL KN DPLNE VVGL Q S+ +A ++
Sbjct: 566 FQKPKPAKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNETVVGLYQKSSVKTLAFLFA 625
Query: 1870 DAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHE 2049
+ + ++E T G + + F+TVS L +E L KLMT LR+T PHFVRCIIPN
Sbjct: 626 ERQ-----SSEEGGTKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 680
Query: 2050 KKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDG 2226
K G + LVL QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L IP+ FID
Sbjct: 681 KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDS 740
Query: 2227 KESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSR 2406
K++ K++ ++DID Y+ G +KVFF+ G+L LEE RD KL LI QA CRGFL R
Sbjct: 741 KKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAMCRGFLMR 800
Query: 2407 RLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRA 2586
+ N A++ +++W W +L+ K+KPLL+ T+ E+ +E
Sbjct: 801 VEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFEK 860
Query: 2587 TKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYI 2766
TKE L K E +E E+K+ ++ E+ +Q Q+Q E++ A+ ++ +L +LE
Sbjct: 861 TKEDLAKSEAKRKELEEKMVALMQEKNDLQLQVQAEADGLADAEERCDQLIKTKIQLEAK 920
Query: 2767 VNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXX 2946
+ ++ +R +RK + + +K +
Sbjct: 921 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 980
Query: 2947 XXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDL 3126
+ L E++ KAK +LE Q+ +LE L
Sbjct: 981 TEEMAGLDENIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSL 1040
Query: 3127 NRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEES 3306
+E++ + +LE+ KRKL +L+ +++ + ++L+ +L K++ E+ + ++ ++E
Sbjct: 1041 EQEKKLRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDEQ 1100
Query: 3307 ANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT 3486
A +QK+++++Q +EL E++E ER +R KAE R ++ +LE++ + L++ AT
Sbjct: 1101 ALAMQLQKKIKELQARTEELEEEIEAERASRAKAEKQRSDLSRELEEI-SERLEEAGGAT 1159
Query: 3487 MLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQL 3663
Q M++K E E +R +E+ E + K + V EL +QI+ ++ + +L
Sbjct: 1160 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKL 1219
Query: 3664 EKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLID-- 3837
EK++++ E D+A + + ++ +++K + E L E++ + +EH+R + +
Sbjct: 1220 EKEKSELKMEIDDLASNMETVSKAKGNLEKMCRTLEDQLSEVK---TKEEEHQRLINELS 1276
Query: 3838 -QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRAR 4014
Q R + E +R +E+E + + R T+ K A + +
Sbjct: 1277 AQKARLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEETKAKSALAHAVQ 1336
Query: 4015 QLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDV 4194
+ + L ++ EE + +A L++ + A + R K E Q+ EEL + +
Sbjct: 1337 SSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA 1396
Query: 4195 EHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMA 4365
+ LQ E E + + ++K+++Q E+ED +++E A+ +K+Q+ F+ +A
Sbjct: 1397 QRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKILA 1456
Query: 4366 EERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSIS 4545
E + ++ + +A +E R T + + N + + LE R ++LQQE+ D
Sbjct: 1457 EWKHKYEETQAELEASQKESRSLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTE 1516
Query: 4546 NKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDR 4725
+ GK++HELEK K+ +E E ++++ +EE E +L+ E LR+++ +KSE DR
Sbjct: 1517 QIAEGGKHIHELEKVKKQIEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEIDR 1576
Query: 4726 AISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANR 4905
I+ KD E ++ +R ++ + +++ L+ E R ++ A+ +KK+E + E+E QL ANR
Sbjct: 1577 KIAEKDEEIDQMKRNHIRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANR 1636
Query: 4906 LKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEG 5085
E + Q+ ++A + ++D+ L +R+ ++AE E+LR + E
Sbjct: 1637 QATEAIRNLRNTQGVLKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEIEELRASLEQ 1696
Query: 5086 LMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDK 5256
++R+ Q K++LE I+Q A +K
Sbjct: 1697 TERSRRVAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEK 1756
Query: 5257 QRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAA 5436
+KA + +L E+ + E K+++E++ +D + ++ E E A + Q+
Sbjct: 1757 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQK 1816
Query: 5437 LEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLK 5616
LEA+V+ LE+++ E + A + R+ E+R+ + T Q E++++ + ++L++K K
Sbjct: 1817 LEARVRELENEVENEQKRNVEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQSK 1876
Query: 5617 NRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+ +RQ +EAE++ + +K R +Q E ++
Sbjct: 1877 VKAYKRQAEEAEEQSNVNLSKFRKLQHELEE 1907
Score = 165 bits (417), Expect = 1e-38
Identities = 191/934 (20%), Positives = 394/934 (41%), Gaps = 48/934 (5%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + + ++DL + + ELE+ L+ E D + + A+ + EE +
Sbjct: 849 KEMANMKEEFEKTKEDLAKSEAKRKELEEKMVALMQEKNDLQLQVQAEADGLADAEERCD 908
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE N L K+ R ++ EL++D++ E
Sbjct: 909 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKDIDD-------LE 960
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E L + +++ +E A + A +Q ++ +
Sbjct: 961 LTLAKVEKEKHATENKVKNLTEEMAGLDENIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1020
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIAL-LQASRADID 3750
+ + K K +QV++L +EQ KK R LE+ + + + + +AQE + ++ + +D
Sbjct: 1021 TLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGD-LKLAQESTMDIENDKQQLD 1079
Query: 3751 KKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLA 3930
+K K E + +Q+ + E ++ L QL++ EL R E EE A R
Sbjct: 1080 EKLKKKEFEMSNLQSKI----EDEQALAMQLQKKIKELQ--ARTEELEEEIEAERASRAK 1133
Query: 3931 TAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQ 4110
RL+ A + Q+E +++K EAE
Sbjct: 1134 AEKQRSDLSRELEEISERLEEAGGATSAQIE------MNKKREAE--------------- 1172
Query: 4111 GAGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELE 4281
+ RR EE+ Q LRKK+ V L +Q++ + K+++ + K +++ E++
Sbjct: 1173 -FQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSELKMEID 1231
Query: 4282 DSSMELENVRASHRDSEKRQKKFESQMAE------------ERVAVQKALLDRDA--MSQ 4419
D + +E V + + EK + E Q++E ++ QKA L ++ S+
Sbjct: 1232 DLASNMETVSKAKGNLEKMCRTLEDQLSEVKTKEEEHQRLINELSAQKARLQTESGEFSR 1291
Query: 4420 ELRDRETRVLSL-------LNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHE 4578
+L ++E V L +++ +K LEE + + +L +Q S + D + E
Sbjct: 1292 QLDEKEALVSQLSRGKQAFTQQIEELKRQLEEETKAKSALAHAVQSSRHDCDLLREQYEE 1351
Query: 4579 LEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEE 4758
++AK L+ + ++ EV K E+D AI + E EE
Sbjct: 1352 EQEAKAELQRAM-------------------SKANSEVAQWRTKYETD-AIQRTE-ELEE 1390
Query: 4759 KRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXX 4938
++ L ++++D E +E + +++++N++ +L +E +N
Sbjct: 1391 AKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRN 1450
Query: 4939 XXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXX 5118
E++ + EE + E R + V+ E+ + E L + K
Sbjct: 1451 FDKILAEWKHKYEETQAELEASQKESRSLSTELFKVKNAYEESLDQLETLKRENKNLQQE 1510
Query: 5119 XXXXXXXRAKGGGISSE---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQI 5289
A+GG E K+++E + ++ +++ E K + Q++L Q+
Sbjct: 1511 ISDLTEQIAEGGKHIHELEKVKKQIEQEKSELQAALEEAEASLEHEEGKILRIQLELNQV 1570
Query: 5290 TTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAAL------EAKV 5451
++ +++K + + +++ R++ + ++S + R++ AL E +
Sbjct: 1571 KSE------IDRKIAEKDEEIDQMKRNHIRVVESMQSTLDAEIRSRNDALRIKKKMEGDL 1624
Query: 5452 QYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLR 5631
+E QLN ++ T A R R + L DT +D R + KE L + ++
Sbjct: 1625 NEMEIQLNHANRQATEAIRNLRNTQGVLKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQ 1684
Query: 5632 RQLDEAEDEMSRERTKHRNVQREADDLLDANEQL 5733
+++E + + R ++E LLDA+E++
Sbjct: 1685 AEIEELRASLEQTERSRRVAEQE---LLDASERV 1715
Score = 122 bits (306), Expect = 1e-25
Identities = 178/890 (20%), Positives = 361/890 (40%), Gaps = 113/890 (12%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ +E + +E+D ++ ++KL + E + +Q +++ E + +L LQ
Sbjct: 1055 RKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDEQALAMQLQKKIKELQ 1114
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + +R S R ++E + + +
Sbjct: 1115 ARTEELEEEIE--AERASRAKAEKQRSDLSR--ELEEISERLEEAGGATSAQIEMNKKRE 1170
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K L+
Sbjct: 1171 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELG---EQIDNLQRVKQKLEKEKSELK 1227
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K LE+ R L +L + K E + EL+ Q + E
Sbjct: 1228 MEIDDLASNMETVSKAKGNLEKMCRTLEDQLSEVKTKEEEHQRLINELSAQKARLQTESG 1287
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ DE+ A V+ + + + I+EL+ +E E A++ + + ++
Sbjct: 1288 EFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEETKAKSALAHAVQSSRHDCDLLRE 1347
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
++ + LQ MS+ + EV TK + IQ T E +EE K K ++++++ +
Sbjct: 1348 QYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQDAEEH 1405
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME-------I 3789
+E + + LEK + + E D+ ++ A+ A +DKK++ + L E
Sbjct: 1406 VEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKILAEWKHKYEET 1465
Query: 3790 QANLAESDEHKRTLIDQL-------ERSRDELDHLNRVREEEEHAFANMQRRLAT----- 3933
QA L S + R+L +L E S D+L+ L R + + +++ ++A
Sbjct: 1466 QAELEASQKESRSLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKHI 1525
Query: 3934 ------------------AXXXXXXXXXXXXXXTRLKIA-NINRARQLEDEKNALLDEKE 4056
A L+I +N+ + D K A DE+
Sbjct: 1526 HELEKVKKQIEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEI 1585
Query: 4057 E---------AEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN------LRD 4191
+ E +++ L+ EI + R A ++K E +N+ +L N +R+
Sbjct: 1586 DQMKRNHIRVVESMQSTLDAEIRS-RNDALRIKKKMEGDLNEMEIQLNHANRQATEAIRN 1644
Query: 4192 VEHLQKQLEESEVAKERILQSKKKIQQELED-------SSMELENVRASHRDSEKRQKKF 4350
+ + Q L+++++ + ++ + ++++L E+E +RAS +E+ ++
Sbjct: 1645 LRNTQGVLKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEIEELRASLEQTERSRRVA 1704
Query: 4351 ESQM--AEERVAV----------QKALLDRDAMS---------QELRDRETRVLSLLNEV 4467
E ++ A ERV + K L+ D QE R+ E + + +
Sbjct: 1705 EQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDA 1764
Query: 4468 DIMKEHLEES-------DRVRRSLQQELQDSISNKDDFG--------KNVHELEKAKRSL 4602
+M E L++ +R++++++Q ++D D+ K + +LE R L
Sbjct: 1765 AMMAEELKKEQDTSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVREL 1824
Query: 4603 EAEL-NDMRVQMEEL-----------EDNLQIAEDAR--LRLEVTNQALKSESDRAISNK 4740
E E+ N+ + +E + E Q ED + LRL+ L+S+ +A +
Sbjct: 1825 ENEVENEQKRNVEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQSKV-KAYKRQ 1883
Query: 4741 DVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
EAEE+ L + R L++ELE + A S K+ + E+ ++
Sbjct: 1884 AEEAEEQSNVNLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKV 1933
Score = 122 bits (305), Expect = 1e-25
Identities = 131/754 (17%), Positives = 313/754 (41%), Gaps = 43/754 (5%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + E+ + + + + +R +LE++ QE+ D+ ++ AD ++
Sbjct: 848 EKEMANMKEEFEKTKEDLAKSEAKRKELEEKMVALMQEKNDLQLQVQAEADGLADAEERC 907
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ + +E L + + DE L + ++ E A ++
Sbjct: 908 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 967
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ T K+ N+ DE A L ++++A +
Sbjct: 968 KE---------------KHATENKVKNLTEEMAGLDENIAKLTKEKKA----------LQ 1002
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
A Q + + E+ VN L + + K + V+ L+ LE+ + + + ++K+K++ +L
Sbjct: 1003 EAHQQTLDDLQAEEDKVNT-LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDL 1061
Query: 4279 ---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL 4449
++S+M++EN + D + ++K+FE + ++ ++AL + + +++++ + R
Sbjct: 1062 KLAQESTMDIENDK-QQLDEKLKKKEFEMSNLQSKIEDEQALAMQ--LQKKIKELQARTE 1118
Query: 4450 SLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRV 4629
L E++ + ++++ R L +EL++ ++ G + + EAE MR
Sbjct: 1119 ELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR 1178
Query: 4630 QME----------------------ELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
+E EL + + + + +LE LK E D SN +
Sbjct: 1179 DLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNME 1238
Query: 4744 VEAEEKRRGLLKQIRDLENEL-------ENEKRGKSGAVSHRKKIENQIGELEQQLEVAN 4902
++ K L K R LE++L E +R + + + +++ + GE +QL+
Sbjct: 1239 TVSKAK-GNLEKMCRTLEDQLSEVKTKEEEHQRLINELSAQKARLQTESGEFSRQLDEKE 1297
Query: 4903 RLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLR----EADRKFRAVEAEREQLR 5070
L + E + + EE +AK +A ++ + D E E+E
Sbjct: 1298 ALVSQLSRGKQAFTQQIEELKRQLEEETKAKSALAHAVQSSRHDCDLLREQYEEEQEAKA 1357
Query: 5071 EANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAI 5250
E + +A + + E K++L ++ + C
Sbjct: 1358 ELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLE 1417
Query: 5251 DKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQM 5430
+++ Q ++E + D+ + ++++ ++ ++K K E ++ ++ ++ +
Sbjct: 1418 KTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKILAEWKHKYEETQAELEA-SQKES 1476
Query: 5431 AALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSN 5610
+L ++ +++ + R + L++ ++D T+Q + + + +++ ++
Sbjct: 1477 RSLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQIE 1536
Query: 5611 LKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ L+ L+EAE + E K +Q E + +
Sbjct: 1537 QEKSELQAALEEAEASLEHEEGKILRIQLELNQV 1570
Score = 76.6 bits (187), Expect = 7e-12
Identities = 110/521 (21%), Positives = 198/521 (37%), Gaps = 18/521 (3%)
Frame = +1
Query: 4234 KERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAM 4413
K + L + ++E+ + E E + SE ++K+ E +M L A
Sbjct: 837 KIKPLLKSAETEKEMANMKEEFEKTKEDLAKSEAKRKELEEKMVALMQEKNDLQLQVQAE 896
Query: 4414 SQELRDRETRVLSLLN-------EVDIMKEHLEESDRV-------RRSLQQELQDSISNK 4551
+ L D E R L+ ++ + E E+ + + +R L+ E + +
Sbjct: 897 ADGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 956
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQA----LKSES 4719
DD + ++EK K + E ++ ++ +M L++N+ + L+ +Q L++E
Sbjct: 957 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDENIAKLTKEKKALQEAHQQTLDDLQAEE 1016
Query: 4720 DRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
D+ N +A+ K L +Q+ DLE LE EK+ R +E +LE L++A
Sbjct: 1017 DKV--NTLTKAKTK---LEQQVDDLEGSLEQEKK-------LRMDLERAKRKLEGDLKLA 1064
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREAN 5079
+ + + E + ED AL + +K + ++A E+L E
Sbjct: 1065 QESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDEQALAMQLQKKIKELQARTEELEEEI 1124
Query: 5080 EGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQ 5259
E RAK S+ R LE
Sbjct: 1125 EA--------------ERASRAKAEKQRSDLSRELE------------------------ 1146
Query: 5260 RKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAAL 5439
+ +LE+ S + +N+K EAE Q + R +LE A + A AAL
Sbjct: 1147 -EISERLEEAGGATSAQIEMNKKREAEFQKMRR----------DLEE-ATLQHEATAAAL 1194
Query: 5440 EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKN 5619
K D + G++ R ++LEK ++ + +D +E +
Sbjct: 1195 RKK---HADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDD-------LASNMETVSKAK 1244
Query: 5620 RNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
NL + ED++S +TK QR ++L +L E
Sbjct: 1245 GNLEKMCRTLEDQLSEVKTKEEEHQRLINELSAQKARLQTE 1285
>gi|41386691|ref|NP_776542.1| myosin, heavy polypeptide 1, skeletal
muscle, adult [Bos taurus]
gi|21743235|dbj|BAB40921.2| myosin heavy chain 2x [Bos taurus]
Length = 1938
Score = 1122 bits (2901), Expect = 0.0
Identities = 656/1889 (34%), Positives = 1053/1889 (55%), Gaps = 15/1889 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V D E F+ +++ +V + + VT+ D V NPPKFDKIEDM+ +T+L
Sbjct: 39 FVADPKESFVKATVQSREGGKVTAK-TEAGATVTVKEDQVFPMNPPKFDKIEDMAMMTHL 97
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 98 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFS 157
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A K
Sbjct: 158 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKK---------- 207
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
++P G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 208 EEPTSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIE 267
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRF-LVNRG-ITLPNV 981
YLLEKSRV Q + ERS+HIFYQI+ E E LL + Y + V++G IT+P++
Sbjct: 268 TYLLEKSRVTFQLKAERSYHIFYQIMSN-KKPELIEMLLITTNPYDYAYVSQGEITVPSI 326
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
DD +E +T +++ I+GF DE SI ++ AV+ GNL+F Q+++ +QA V K
Sbjct: 327 DDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADK 386
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L GL +L KA PR+KVG EFV K Q EQ AV A+AKA Y+++F W+V RI
Sbjct: 387 AAYLQGLNSADLLKALCYPRVKVGNEFVTKGQTVEQVYNAVGALAKAVYDKMFLWMVARI 446
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 447 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL + H K
Sbjct: 506 KEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDMSFKNKLYEQHLGKSNN 565
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P ++++HF+++HYAG VDY+ WL KN DPLNE VVGL Q S+ +A +
Sbjct: 566 FQKPKPAKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNETVVGLYQKSSVKTLALL-- 623
Query: 1870 DAEFAGICAAEM-NETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNH 2046
F+G + E G + + F+TVS L +E L KLMT LR+T PHFVRCIIPN
Sbjct: 624 ---FSGPASGEAEGGPKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNE 680
Query: 2047 EKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFID 2223
K G + LVL QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L IP+ FID
Sbjct: 681 TKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFID 740
Query: 2224 GKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLS 2403
K++ K++ ++D+D Y+ G +KVFF+ G+L LEE RD KL LI QA+CRGFL+
Sbjct: 741 SKKASEKLLASIDVDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQARCRGFLA 800
Query: 2404 RRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELR 2583
R Y N A++ +++W W +L+ K+KPLL+ T+ E+ +E
Sbjct: 801 RVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFE 860
Query: 2584 ATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEY 2763
TKE L K E +E E+K+ + E+ +Q Q+Q E++ A+ ++ +L +LE
Sbjct: 861 KTKEELAKSEAKRKELEEKMVTLTQEKNDLQLQVQSEADALADAEERCDQLIKTKIQLEA 920
Query: 2764 IVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXX 2943
+ ++ +R +RK + + +K +
Sbjct: 921 KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 980
Query: 2944 XXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQD 3123
+ L E++ KAK +LE Q+ +LE
Sbjct: 981 LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGS 1040
Query: 3124 LNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEE 3303
L +E++ + +LE+ KRKL +L+ +++ + ++L+ +L K++ E+ + ++ ++E
Sbjct: 1041 LEQEKKLRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDE 1100
Query: 3304 SANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEA 3483
A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L++ A
Sbjct: 1101 QALAMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEI-SERLEEAGGA 1159
Query: 3484 TMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQ 3660
T Q M++K E E +R +E+ E + K + V EL +QI+ ++ + +
Sbjct: 1160 TSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQK 1219
Query: 3661 LEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQ 3840
LEK++++ E D+A + + ++ +++K + E L E++ E L Q
Sbjct: 1220 LEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSELKTKEDEQQRLINDLTTQ 1279
Query: 3841 LERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQL 4020
R + E +R +E++ + + R + K A + +
Sbjct: 1280 RARLQTESGEFSRQLDEKDALVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSA 1339
Query: 4021 EDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEH 4200
+ + L ++ EE + +A L++ + A + R K E Q+ EEL + + +
Sbjct: 1340 RHDCDLLREQYEEEQEGKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1399
Query: 4201 LQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEE 4371
LQ E E + + ++K+++Q E+ED +++E A+ +K+Q+ F+ ++E
Sbjct: 1400 LQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILSEW 1459
Query: 4372 RVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNK 4551
+ ++ + +A +E R T + + N + + LE R ++LQQE+ D
Sbjct: 1460 KQKYEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQI 1519
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAI 4731
+ GK +HELEK K+ +E E ++++ +EE E +L+ E LR+++ +KSE DR I
Sbjct: 1520 AEGGKRIHELEKVKKQVEQEKSEIQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKI 1579
Query: 4732 SNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLK 4911
+ KD E ++ +R ++ + +++ L+ E R ++ A+ +KK+E + E+E QL ANR+
Sbjct: 1580 AEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA 1639
Query: 4912 EEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLM 5091
E + QI ++A + +ED+ L +R+ ++AE E+LR E
Sbjct: 1640 AEALKNYRSTQAILKDTQIHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQTE 1699
Query: 5092 QARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQR 5262
++RK Q K++LE I Q A +K +
Sbjct: 1700 RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDITQIQGEMEDIIQEARNAEEKAK 1759
Query: 5263 KAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALE 5442
KA + +L E+ + E K++LE++ +D + ++ E E A + Q+ LE
Sbjct: 1760 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1819
Query: 5443 AKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNR 5622
A+V+ LE ++ E + A + R+ E+R+ + T Q E++++ + ++L++K K +
Sbjct: 1820 ARVRELEGEVESEQKRNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVK 1879
Query: 5623 NLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+ +RQ +EAE++ + +K R +Q E ++
Sbjct: 1880 SYKRQAEEAEEQSNVNLSKFRKLQHELEE 1908
Score = 159 bits (401), Expect = 1e-36
Identities = 195/930 (20%), Positives = 382/930 (40%), Gaps = 32/930 (3%)
Frame = +1
Query: 3040 LLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSE---LEQHKRKLLAELEDSKDHL 3210
LL E K K E EL + + ++ + + L Q K L +++ D L
Sbjct: 842 LLKSAETEKEMANMKEEFEKTKEELAKSEAKRKELEEKMVTLTQEKNDLQLQVQSEADAL 901
Query: 3211 AEKMGKVEELNNQLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELRED 3375
A+ EE +QL+K +L+ ++ DEE N L K+ R ++ EL++D
Sbjct: 902 AD----AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKD 956
Query: 3376 METERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQI 3555
++ E+T +V + + V + +E L + +++ +E A + A +Q
Sbjct: 957 IDD-------LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQT 1009
Query: 3556 QHTMEGK------IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEI 3717
++ + + + K K +QV++L +EQ KK R LE+ + + + + +AQE
Sbjct: 1010 LDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGD-LKLAQES 1068
Query: 3718 AL-LQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEE 3894
+ ++ + +D+K K E + +Q+ + E ++ L QL++ EL R+ E E
Sbjct: 1069 TMDIENDKQQLDEKLKKKEFEMSNLQSKI----EDEQALAMQLQKKIKELQ--ARIEELE 1122
Query: 3895 EHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLR 4074
E A R RL+ A + Q+E +++K EAE
Sbjct: 1123 EEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIE------MNKKREAE--- 1173
Query: 4075 AHLEKEIHAARQGAGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERI 4245
+ RR EE+ Q LRKK+ V L +Q++ + K+++
Sbjct: 1174 -------------FQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKL 1220
Query: 4246 LQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQEL 4425
+ K +++ E++D + +E V + + EK + E Q++E + D + +
Sbjct: 1221 EKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSELKT-------KEDEQQRLI 1273
Query: 4426 RDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLE 4605
D T+ L E L+E D + L + Q ++ + + E KAK +L
Sbjct: 1274 NDLTTQRARLQTESGEFSRQLDEKDALVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALA 1333
Query: 4606 AELNDMRVQMEELEDNLQIAEDARLRL---------EVTNQALKSESDRAISNKDVEAEE 4758
L R + L + + ++ + L EV K E+D AI + E EE
Sbjct: 1334 HALQSARHDCDLLREQYEEEQEGKAELQRAMSKANSEVAQWRTKYETD-AIQRTE-ELEE 1391
Query: 4759 KRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXX 4938
++ L ++++D E +E + +++++N++ +L +E N
Sbjct: 1392 AKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRN 1451
Query: 4939 XXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXX 5118
E++ + EE E R + ++ E+ + E L + K
Sbjct: 1452 FDKILSEWKQKYEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQE 1511
Query: 5119 XXXXXXXRAKGGGISSE---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQI 5289
A+GG E K+++E + ++ +++ E K + Q++L Q+
Sbjct: 1512 ISDLTEQIAEGGKRIHELEKVKKQVEQEKSEIQAALEEAEASLEHEEGKILRIQLELNQV 1571
Query: 5290 TTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSR--ARAQMAALEAKVQYLE 5463
+++ +R + +K E Q R ++ + L++ +SR A +E + +E
Sbjct: 1572 KSEI--DRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEME 1629
Query: 5464 DQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLD 5643
QLN + A + R + L DT +D R E KE L + L+ +++
Sbjct: 1630 IQLNHANRMAAEALKNYRSTQAILKDTQIHLDDALRGQEDLKEQLAMVERRANLLQAEIE 1689
Query: 5644 EAEDEMSRERTKHRNVQREADDLLDANEQL 5733
E + + + ++E LLDA+E++
Sbjct: 1690 ELRATLEQTERSRKIAEQE---LLDASERV 1716
Score = 116 bits (290), Expect = 8e-24
Identities = 168/888 (18%), Positives = 348/888 (38%), Gaps = 111/888 (12%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ +E + +E+D ++ ++KL + E + +Q +++ E + +L LQ
Sbjct: 1056 RKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDEQALAMQLQKKIKELQ 1115
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + +R S R ++E + + +
Sbjct: 1116 ARIEELEEEIE--AERASRAKAEKQRSDLSR--ELEEISERLEEAGGATSAQIEMNKKRE 1171
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K ++
Sbjct: 1172 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELG---EQIDNLQRVKQKLEKEKSEMK 1228
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K LE+ R L +L + K E+ + +L Q + E
Sbjct: 1229 MEIDDLASNMETVSKAKGNLEKMCRALEDQLSELKTKEDEQQRLINDLTTQRARLQTESG 1288
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ DE+ A V+ + + + I+EL+ +E E A++ + + ++
Sbjct: 1289 EFSRQLDEKDALVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSARHDCDLLRE 1348
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
++ + LQ MS+ + EV TK + IQ T E +EE K K ++++++ +
Sbjct: 1349 QYEEEQEGKAELQRAMSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQDAEEH 1406
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME-------I 3789
+E + + LEK + + E D+ ++ A+ A +DKK++ + L E
Sbjct: 1407 VEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILSEWKQKYEET 1466
Query: 3790 QANLAESDEHKRTLIDQL-------ERSRDELDHLNRVREEEEHAFANMQRRLATAXXXX 3948
A L S + R+L +L E S D+L+ L R + + +++ ++A
Sbjct: 1467 HAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRI 1526
Query: 3949 XXXXXXXXXX----TRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGA 4116
+ ++ A LE E+ +L + E +++ ++++I +
Sbjct: 1527 HELEKVKKQVEQEKSEIQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEI 1586
Query: 4117 GEARR---KAEESVNQQLE----------ELRKKNLRDVEHLQKQLEESEVAKERILQSK 4257
+ +R + ES+ L+ L+KK D+ ++ QL + L++
Sbjct: 1587 DQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALKNY 1646
Query: 4258 KKIQQELEDSSMELENVRASHRDS-------EKRQKKFESQMAEERVAVQKALLDRDAMS 4416
+ Q L+D+ + L++ D E+R ++++ E R +++ R
Sbjct: 1647 RSTQAILKDTQIHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAE 1706
Query: 4417 QELRDRETRV-------LSLLN-----EVDI------MKEHLEESDRVRRSLQQELQDSI 4542
QEL D RV SL+N E DI M++ ++E+ ++ + D+
Sbjct: 1707 QELLDASERVQLLHTQNTSLINTKKKLETDITQIQGEMEDIIQEARNAEEKAKKAITDAA 1766
Query: 4543 SNKDDFGKNVH---ELEKAKRSLEAELNDMRVQMEELED------NLQIAE-DARLR--- 4683
++ K LE+ K++LE + D++ +++E E QI + +AR+R
Sbjct: 1767 MMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELE 1826
Query: 4684 ---------------------LEVTNQALKSESDR------------------AISNKDV 4746
V ++E DR + +
Sbjct: 1827 GEVESEQKRNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAE 1886
Query: 4747 EAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
EAEE+ L + R L++ELE + A S K+ + E+ ++
Sbjct: 1887 EAEEQSNVNLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKI 1934
Score = 75.9 bits (185), Expect = 1e-11
Identities = 112/521 (21%), Positives = 203/521 (38%), Gaps = 11/521 (2%)
Frame = +1
Query: 4213 LEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQK- 4389
L+ +E KE +++E E + EL A ++ E++ + + ++ VQ
Sbjct: 843 LKSAETEKEMA-----NMKEEFEKTKEELAKSEAKRKELEEKMVTLTQEKNDLQLQVQSE 897
Query: 4390 --ALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNK---- 4551
AL D + +L + ++ + + EV E EE + + +++L+D S
Sbjct: 898 ADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 957
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQA----LKSES 4719
DD + ++EK K + E ++ ++ +M L++ + + L+ +Q L++E
Sbjct: 958 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1017
Query: 4720 DRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
D+ N +A+ K L +Q+ DLE LE EK+ R +E +LE L++A
Sbjct: 1018 DKV--NTLTKAKTK---LEQQVDDLEGSLEQEKK-------LRMDLERAKRKLEGDLKLA 1065
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREAN 5079
+ + + E + ED AL + +K + ++A E+L E
Sbjct: 1066 QESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDEQALAMQLQKKIKELQARIEELEEEI 1125
Query: 5080 EGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQ 5259
E RAK S+ R LE
Sbjct: 1126 EA--------------ERASRAKAEKQRSDLSRELE------------------------ 1147
Query: 5260 RKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAAL 5439
+ +LE+ S + +N+K EAE Q + R +LE A + A AAL
Sbjct: 1148 -EISERLEEAGGATSAQIEMNKKREAEFQKMRR----------DLEE-ATLQHEATAAAL 1195
Query: 5440 EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKN 5619
K D + G++ R ++LEK ++ + +D +E +
Sbjct: 1196 RKK---HADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDD-------LASNMETVSKAK 1245
Query: 5620 RNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
NL + ED++S +TK QR +DL +L E
Sbjct: 1246 GNLEKMCRALEDQLSELKTKEDEQQRLINDLTTQRARLQTE 1286
>gi|3915779|sp|P13539|MYH6_MESAU Myosin heavy chain, cardiac muscle
alpha isoform (MyHC-alpha)
gi|2119307|pir||I48175 myosin heavy chain alpha, cardiac muscle
[similarity] - golden hamster
gi|402374|gb|AAB59701.1| alpha-cardiac myosin heavy chain gene
Length = 1939
Score = 1122 bits (2901), Expect = 0.0
Identities = 659/1917 (34%), Positives = 1057/1917 (54%), Gaps = 45/1917 (2%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
R C+VPD E F+ I +V E + + VT+ D V + NPPKFDKIEDM+
Sbjct: 34 RTECFVPDDKEEFVKAKIVSREGGKVTAE-TENGKTVTVKEDQVMQQNPPKFDKIEDMAM 92
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LT+L+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E P
Sbjct: 93 LTFLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPA 152
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAG-ATRNKSLNAAA 612
HIF+I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A R+K N A
Sbjct: 153 HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRSKKDNPNA 212
Query: 613 QQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYIS 792
+ G LE Q++QANP LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++
Sbjct: 213 NK------------GTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLA 260
Query: 793 GANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLL--EGVDNYRFLVNRGI 966
A+IE YLLEKSRV+ Q + ER++HIFYQIL E + LL +Y F+ +
Sbjct: 261 SADIETYLLEKSRVIFQLKAERNYHIFYQILSN-KKPELLDMLLVTNNPYDYAFVSQGEV 319
Query: 967 TLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDD 1146
++ ++DD +E +T ++ ++GF +E + + ++ A++ GN++F Q+++ +QA
Sbjct: 320 SVASIDDSEELLATDSAFDVLGFTAEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGT 379
Query: 1147 RVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKW 1326
K +L+GL +L K PR+KVG E+V K Q+ +Q +++ A+ K+ YE++F W
Sbjct: 380 EDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALGKSVYEKMFNW 439
Query: 1327 LVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILE 1506
+VTRIN +L+ T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF+LE
Sbjct: 440 MVTRINATLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLE 498
Query: 1507 QEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH- 1683
QEEY++EGIEW+FIDFG+DLQ IDLIEKPMG++++L+EEC+FPKA D +F KL H
Sbjct: 499 QEEYKKEGIEWEFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLYDNHL 558
Query: 1684 NKHPKFIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFV 1854
K F P + ++HF++VHYAG VDY+ WL KN DPLNE VVGL Q S+ +
Sbjct: 559 GKSNNFQKPRNVKGKQEAHFSLVHYAGTVDYNILGWLEKNKDPLNETVVGLYQKSSLKLM 618
Query: 1855 AGIWKDAEFAGICAAEMNETAFGMRSRK--GMFRTVSQLHKEQLTKLMTTLRNTSPHFVR 2028
A + F+ +A+ ++ G +K F+TVS LH+E L KLMT LR T PHFVR
Sbjct: 619 ATL-----FSTYASADAGDSGKGKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPHFVR 673
Query: 2029 CIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIP 2208
CIIPN K G +++ LV+ QLRCNGVLEGIRICR+GFPNR+ + +FR RY IL P IP
Sbjct: 674 CIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIP 733
Query: 2209 KN-FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQ 2385
+ FID ++ K++++LDID N Y+ G +KVFF+ G+L LEE RD +L+ +I QAQ
Sbjct: 734 EGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQ 793
Query: 2386 CRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRA 2565
RG L R + N A++ ++NW W +L+ K+KPLL+ T+ E+
Sbjct: 794 ARGQLMRIEFKKMVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMAN 853
Query: 2566 KDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTR 2745
+E KE L K E +E E+K+ ++ E+ +Q Q+Q E +N + ++ +L
Sbjct: 854 MKEEFGRVKESLEKSEARRKELEEKMVSLLQEKNDLQFQVQAEQDNLNDAEERCDQLIKN 913
Query: 2746 NQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNV 2925
+LE V +M +RL +RK + + +K
Sbjct: 914 KIQLEAKVKEMTERLEDEEEMNAELTSKKRKLEDECSELKKDIDDLELTLAKVEKEKHAT 973
Query: 2926 DQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQL 3105
+ + L E++ K+K +LE Q+
Sbjct: 974 ENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKSKVKLEQQV 1033
Query: 3106 HELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQL 3285
+LE L +E++ + +LE+ KRKL +L +++ + + +L +L K++ ++ Q
Sbjct: 1034 DDLEGSLEQEKKVRMDLERAKRKLEGDLNVTQESIMDLENDKLQLEEKLKKKEFDISQQN 1093
Query: 3286 TRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVL 3465
++ ++E A +QK++++ Q I+EL E++E ER AR K E R ++ +LE++ + L
Sbjct: 1094 SKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLTRELEEIS-ERL 1152
Query: 3466 DKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQH 3642
++ AT +Q M++K E E +R +E+ E + K + V EL +QI+
Sbjct: 1153 EEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 1212
Query: 3643 KKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHK 3822
++ + +LEK++++ E D+ + + ++A+++K + E E + L ES
Sbjct: 1213 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEESQRSL 1272
Query: 3823 RTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANI 4002
Q + + E L R EE+E + + R + + K A
Sbjct: 1273 NDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALA 1332
Query: 4003 NRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN 4182
+ + + + L ++ EE +A L++ + A + R K E Q+ EEL +
Sbjct: 1333 HALQSARHDCDLLREQYEEEMEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAK 1392
Query: 4183 LRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFE 4353
+ + LQ E E + + ++K ++Q E+ED +++E A+ +K+Q+ F+
Sbjct: 1393 KKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFD 1452
Query: 4354 SQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQ 4533
+AE + +++ + ++ +E R T + L N + EHLE R ++LQ+E+
Sbjct: 1453 KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEIS 1512
Query: 4534 DSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKS 4713
D + GKNVHELEK ++ LE E +++ +EE E +L+ E LR ++ +K+
Sbjct: 1513 DLTEQLGEGGKNVHELEKVRKQLEVEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKA 1572
Query: 4714 ESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLE 4893
E +R ++ KD E E+ +R L+ + L+ L+ E R ++ A+ +KK+E + E+E QL
Sbjct: 1573 EIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLS 1632
Query: 4894 VANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLRE 5073
ANR+ E + Q++ ++A A +D+ + +R+ ++AE E+LR
Sbjct: 1633 QANRIASEAQKHLKNAQAHLKDTQLQLDDALHANDDLKENIAIVERRNTLLQAELEELRA 1692
Query: 5074 ANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCEL 5244
E ++RK Q +K+++EA + Q C
Sbjct: 1693 VVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMEADLTQLQTEVEEAVQECRN 1752
Query: 5245 AIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARA 5424
A +K +KA + +L E+ + E K+++E++ +D + ++ E E A +
Sbjct: 1753 AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKK 1812
Query: 5425 QMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEK 5604
Q+ LEA+V+ LE++L E + + + R+ E+R+ + T Q E++K+ + ++L++K
Sbjct: 1813 QLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLVRLQDLVDK 1872
Query: 5605 SNLKNRNLRRQ---------------------LDEAED-------EMSRERTKHRNV 5691
LK + +RQ LDEAE+ ++++ R K R++
Sbjct: 1873 LQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDI 1929
Score = 158 bits (399), Expect = 2e-36
Identities = 191/876 (21%), Positives = 371/876 (41%), Gaps = 20/876 (2%)
Frame = +1
Query: 3181 AELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTID 3360
AE E ++ E+ G+V+E + R +EL+ ++ V+L+Q++ +
Sbjct: 845 AETEKEMANMKEEFGRVKESLEKSEARRKELEEKM---------VSLLQEK--------N 887
Query: 3361 ELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT-MLQDLMSRKDEEVNATK 3537
+L+ ++ E++ N AE E QL K K + KV E T L+D +EE+NA
Sbjct: 888 DLQFQVQAEQDNLNDAE----ERCDQLIKNKIQLEAKVKEMTERLED-----EEEMNA-- 936
Query: 3538 RAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEI 3717
++ +K K + EL I+ + +++EK+++ + + ++ +E+
Sbjct: 937 ------------ELTSKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEM 984
Query: 3718 ALLQASRADIDKKRK-IHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEE 3894
A L A + K++K + EAH + AE D+ TL + ++D L E+E
Sbjct: 985 AGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK-VNTLTKSKVKLEQQVDDLEGSLEQE 1043
Query: 3895 EHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLR 4074
+ +++R R+LE + N + + E +
Sbjct: 1044 KKVRMDLERA----------------------------KRKLEGDLNVTQESIMDLENDK 1075
Query: 4075 AHLEKEIHAARQGAGEARRKAEE--SVNQQLEELRKKNLRDVEHLQKQLEESEVAKERIL 4248
LE+++ + K E+ ++ QL++ K+N +E L+++LE A+ ++
Sbjct: 1076 LQLEEKLKKKEFDISQQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVE 1135
Query: 4249 QSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELR 4428
+ + + +ELE+ S LE + + KK E++ + R +++A L +A + LR
Sbjct: 1136 KLRSDLTRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALR 1195
Query: 4429 DRETRVLSLLNE-VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLE 4605
+ ++ L E +D ++ ++ ++ + + EL D SN + K LEK R+LE
Sbjct: 1196 KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLE 1255
Query: 4606 AELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLL--- 4776
+ N+ RV++EE + +L R +L+ N E R + K+ + RG L
Sbjct: 1256 DQANEYRVKLEESQRSLNDFTTQRAKLQTEN----GELARQLEEKEALISQLTRGKLSYT 1311
Query: 4777 KQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXX 4956
+Q+ DL+ +LE E + K+ + + L +Q E K E
Sbjct: 1312 QQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEEMEAKAELQRVLSKANSEVA 1371
Query: 4957 EYQIE--------CEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXX 5112
+++ + EE +AK+ +A L++A+ AV A+ L + R Q
Sbjct: 1372 QWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKH-----RLQNE 1426
Query: 5113 XXXXXXXXXRAKGGGISSEEKRRLEAKI-AQXXXXXXXXQSNCELAIDKQRKAQVQLEQI 5289
R+ + ++K+R KI A+ QS E +Q + +
Sbjct: 1427 IEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE-------SSQKEARSL 1479
Query: 5290 TTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLED- 5466
+T+L + +++ ++ +R N++ + +I++L Q+ V LE
Sbjct: 1480 STELFKLKNAYEESLEHLETFKRENKNLQEEISDLTE--------QLGEGGKNVHELEKV 1531
Query: 5467 --QLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQL 5640
QL VE E L+ L + E E+ +A+ LE + +K + R+L
Sbjct: 1532 RKQLEVEKME----------LQSALEEAEASLEHEEGKILRAQ--LEFNQIK-AEIERKL 1578
Query: 5641 DEAEDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
E ++EM + + H V LDA + E +
Sbjct: 1579 AEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEAL 1614
Score = 130 bits (326), Expect = 5e-28
Identities = 144/755 (19%), Positives = 314/755 (41%), Gaps = 44/755 (5%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + + + +E+ + +R +LE++ QE+ D+ ++ Q + D ++
Sbjct: 848 EKEMANMKEEFGRVKESLEKSEARRKELEEKMVSLLQEKNDLQFQVQAEQDNLNDAEERC 907
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ L + +E L + + DE L + ++ E A ++
Sbjct: 908 DQLIKNKIQLEAKVKEMTERLEDEEEMNAELTSKKRKLEDECSELKKDIDDLELTLAKVE 967
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ K A N+ + L +E A LDE + A L KE
Sbjct: 968 KE---------------------KHATENKVKNLTEEM-AGLDE------IIAKLTKEKK 999
Query: 4099 AARQGAGEARR--KAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQ 4272
A ++ +A +AEE L + + K + V+ L+ LE+ + + + ++K+K++
Sbjct: 1000 ALQEAHQQALDDLQAEEDKVNTLTKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEG 1059
Query: 4273 EL---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETR 4443
+L ++S M+LEN + + K+ K+F+ ++ ++AL + + ++L++ + R
Sbjct: 1060 DLNVTQESIMDLENDKLQLEEKLKK-KEFDISQQNSKIEDEQALALQ--LQKKLKENQAR 1116
Query: 4444 VLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDM 4623
+ L E++ + + +++R L +EL++ ++ G + + EAE M
Sbjct: 1117 IEELEEELEAERTARAKVEKLRSDLTRELEEISERLEEAGGATSVQIEMNKKREAEFQKM 1176
Query: 4624 RVQME----------------------ELEDNLQIAEDARLRLEVTNQALKSESDRAISN 4737
R +E EL + + + + +LE K E D SN
Sbjct: 1177 RRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 1236
Query: 4738 KD--VEAEEKRRGLLKQIRDLENE----LENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
+ ++A+ + + + D NE LE +R + + R K++ + GEL +QLE
Sbjct: 1237 MEQIIKAKANLEKVSRTLEDQANEYRVKLEESQRSLNDFTTQRAKLQTENGELARQLEEK 1296
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA----DRKFRAVEAEREQL 5067
L + + + + EE +AK +A L+ A D E E E
Sbjct: 1297 EALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEEMEAK 1356
Query: 5068 REANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELA 5247
E L +A + + E K++L ++ + C
Sbjct: 1357 AELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSL 1416
Query: 5248 IDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQ 5427
+ + Q ++E + D+ + ++++ ++ ++K K E +S +S ++ +
Sbjct: 1417 EKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELES-SQKE 1475
Query: 5428 MAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKS 5607
+L ++ L++ + R + L++ ++D T+Q + + + +++ ++
Sbjct: 1476 ARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQL 1535
Query: 5608 NLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
++ L+ L+EAE + E K Q E + +
Sbjct: 1536 EVEKMELQSALEEAEASLEHEEGKILRAQLEFNQI 1570
>gi|45383668|ref|NP_989559.1| myosin, heavy polypeptide 2, skeletal
muscle, adult [Gallus gallus]
gi|9800486|gb|AAF99314.1| fast myosin heavy chain isoform 2 [Gallus
gallus]
Length = 1944
Score = 1121 bits (2899), Expect = 0.0
Identities = 655/1896 (34%), Positives = 1058/1896 (55%), Gaps = 22/1896 (1%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V E F+ G+I+ + +V V+ + +T+ D + NPPK+DKIEDM+ +T+L
Sbjct: 40 FVVHPKESFVKGTIQSKETGKVTVK-TEGGETLTVKEDQIFSMNPPKYDKIEDMAMMTHL 98
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 99 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVLAYRGKKRQEAPPHIFS 158
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A + K +
Sbjct: 159 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAASGEKKKEEQPGKMQ-- 216
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 217 ---------GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIE 267
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLL-EGVDNYRFLVNRGITLPNVD 984
YLLEKSRV Q + ERS+HIFYQI+ + L+ +Y F+ IT+P+++
Sbjct: 268 TYLLEKSRVTFQLKAERSYHIFYQIMSNKKPELIGMLLITTNPYDYHFVSQGEITVPSIN 327
Query: 985 DVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQKV 1164
D +E +T +++ I+GF DE +I ++ AV+ GNL+F Q+++ +QA V K
Sbjct: 328 DQEELMATDSAIDILGFTADEKVAIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKA 387
Query: 1165 CHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRIN 1344
+L+GL +L KA PR+KVG E+V K Q +Q +V A+AKA YE++F W+V RIN
Sbjct: 388 AYLMGLNSADLLKALCYPRVKVGNEYVTKGQTVQQVNNSVGALAKAVYEKMFLWMVVRIN 447
Query: 1345 KSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQR 1524
+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY++
Sbjct: 448 QQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKK 506
Query: 1525 EGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPKF 1701
EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H K F
Sbjct: 507 EGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSSNF 566
Query: 1702 IVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWKD 1872
P ++++HF++VHYAG VDY+ WL KN DPLNE V+GL Q S+ +A +
Sbjct: 567 QKPKPAKGKAEAHFSLVHYAGTVDYNITGWLEKNKDPLNETVIGLYQKSSVKTLALL--- 623
Query: 1873 AEFAGICAAEMNETAFGMRSRKG------MFRTVSQLHKEQLTKLMTTLRNTSPHFVRCI 2034
FA AE + G +KG F+TVS L +E L LMT LR+T PHFVRCI
Sbjct: 624 --FANYGGAEAEASGGGGGGKKGGKKKGSSFQTVSALFRENLNNLMTNLRSTHPHFVRCI 681
Query: 2035 IPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK- 2211
IPN K G + LVL QLRCNGVLEGIRICR+GFP+RV + +F+ RY++L IP+
Sbjct: 682 IPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRVLYADFKQRYKVLNASAIPEG 741
Query: 2212 NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCR 2391
FID K++ K++ ++D+D Y+ G +KVFF+ G+L LEE RD KL LI QA+CR
Sbjct: 742 QFIDSKKASEKLLGSIDVDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQARCR 801
Query: 2392 GFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKD 2571
GFL R A++ +++W W +L K+KPLL+ ++ E+
Sbjct: 802 GFLMRVESQRMVERRESIFCIQSMFGAFMNVKHWPWMKLSFKIKPLLKSAESEKEMANMK 861
Query: 2572 DELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQ 2751
+E TKE L K E +E E+K+ +++ E+ +Q Q+Q E++ A+ ++ +L
Sbjct: 862 EEFEKTKEELAKSEAKRKELEEKMVKLVQEKNDLQLQVQAEADALADAEERCDQLIKTKI 921
Query: 2752 ELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQ 2931
+LE + ++ +R +RK + + +K +
Sbjct: 922 QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 981
Query: 2932 XXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHE 3111
+ L E++ KAK +LE Q+ +
Sbjct: 982 KVKNLTEEMAALDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDD 1041
Query: 3112 LEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTR 3291
LE L +E++ + +LE+ KRKL +L+ S+D + + ++L+ +L K+D E+ ++
Sbjct: 1042 LEGSLEQEKKLRMDLERAKRKLEGDLKMSQDTIMDLENDKQQLDEKLKKKDFEISQIQSK 1101
Query: 3292 YDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDK 3471
++E A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L++
Sbjct: 1102 IEDEQALGMQLQKKIKELQARIEELEEEIEAERTSRAKAEKHRADLSRELEEI-SERLEE 1160
Query: 3472 VDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKK 3648
AT Q D+ +++ E +R +E+ E + K + EL +QI+ ++
Sbjct: 1161 AGGATATQIDMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQR 1220
Query: 3649 QRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRT 3828
+ +LEK++++ E D+A + + ++A+++K + E L +I+ ++ +EH+R
Sbjct: 1221 VKQKLEKEKSELKMEIDDLASNMESVSKAKANLEKMCRTLEDQLSKIK---SKEEEHQRM 1277
Query: 3829 LID---QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIAN 3999
+ D Q R + E +R EE++ + + R + K A
Sbjct: 1278 INDLSTQRARLQTESGEYSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKNAL 1337
Query: 4000 INRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKK 4179
+ + + + L ++ EE + + L++ + A + R K E Q+ EEL +
Sbjct: 1338 AHALQSARHDCDLLREQYEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEELEEA 1397
Query: 4180 NLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKF 4350
+ + LQ E E + + ++K+++Q E+ED +++E A+ +K+QK F
Sbjct: 1398 KKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERANAACARLDKKQKNF 1457
Query: 4351 ESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQEL 4530
+ +AE + ++ + +A +E R T + + N + +HLE R ++LQQE+
Sbjct: 1458 DKILAEWKQKYEETQAELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEI 1517
Query: 4531 QDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALK 4710
D + GK +HELEK K+ +E E ++++ +EE E +L+ E LRL++ +K
Sbjct: 1518 SDLTEQIAEGGKAIHELEKVKKQIEQEKSEIQAALEEAEASLEHEEGKILRLQLELNQVK 1577
Query: 4711 SESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
SE DR I+ KD E ++ +R L+ + +++ L+ E R ++ A+ +KK+E + E+E QL
Sbjct: 1578 SEIDRKIAEKDEEIDQLKRNHLRIVESMQSTLDAEIRSRNEALRLKKKMEGDLNEMEIQL 1637
Query: 4891 EVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLR 5070
ANR+ E + QI ++A + +ED+ + +R+ ++AE E+LR
Sbjct: 1638 NHANRVAAEAQKNLRNTQGVLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEIEELR 1697
Query: 5071 EANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCE 5241
A E ++RK Q K++LE IAQ
Sbjct: 1698 AALEQTERSRKVAEQELMDASERVQLLHTQNTSLINTKKKLETDIAQIQSEMEDTIQEAR 1757
Query: 5242 LAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRAR 5421
A +K +KA + +L E+ + E K++L+++ +D + ++ E E A +
Sbjct: 1758 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLDQTVKDLQLRLDEAEQLALKGGK 1817
Query: 5422 AQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLE 5601
Q+ LEA+V+ LE +++ E + A + R+ E+R+ + T Q E++++ + ++L++
Sbjct: 1818 KQIQKLEARVRELEGEVDAEQKRSAEAVKGVRKYERRVKELTYQSEEDRKNILRLQDLVD 1877
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
K +K ++ +RQ +EAE+ + TK R +Q E ++
Sbjct: 1878 KLQMKVKSYKRQAEEAEELSNVNLTKFRKIQHELEE 1913
Score = 163 bits (412), Expect = 5e-38
Identities = 187/925 (20%), Positives = 389/925 (41%), Gaps = 39/925 (4%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + + +++L + + ELE+ KL+ E D + + A+ + EE +
Sbjct: 855 KEMANMKEEFEKTKEELAKSEAKRKELEEKMVKLVQEKNDLQLQVQAEADALADAEERCD 914
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE N L K+ R ++ EL++D++ E
Sbjct: 915 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKDIDD-------LE 966
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E L + +++ +E A + A +Q ++ +
Sbjct: 967 LTLAKVEKEKHATENKVKNLTEEMAALDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1026
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK 3753
+ + K K +QV++L +EQ KK R LE+ + + + + I L+ + +D+
Sbjct: 1027 TLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKMSQDTIMDLENDKQQLDE 1086
Query: 3754 KRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLAT 3933
K K + + +IQ+ + E ++ L QL++ EL R+ E EE A R
Sbjct: 1087 KLKKKDFEISQIQSKI----EDEQALGMQLQKKIKELQ--ARIEELEEEIEAERTSRAKA 1140
Query: 3934 AXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQG 4113
RL+ A A Q++ +++K EAE
Sbjct: 1141 EKHRADLSRELEEISERLEEAGGATATQID------MNKKREAE---------------- 1178
Query: 4114 AGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELED 4284
+ RR EE+ Q LRKK+ L +Q++ + K+++ + K +++ E++D
Sbjct: 1179 FQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDD 1238
Query: 4285 SSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNE 4464
+ +E+V + + EK + E Q++ K + + + D T+ L E
Sbjct: 1239 LASNMESVSKAKANLEKMCRTLEDQLS-------KIKSKEEEHQRMINDLSTQRARLQTE 1291
Query: 4465 VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEEL 4644
+EE D + L + Q ++ +++ E KAK +L L R + L
Sbjct: 1292 SGEYSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKNALAHALQSARHDCDLL 1351
Query: 4645 EDNLQIAEDARLRL---------EVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLE 4797
+ + ++A+ L EV K E+D AI + E EE ++ L ++++D E
Sbjct: 1352 REQYEEEQEAKGELQRALSKANSEVAQWRTKYETD-AIQRTE-ELEEAKKKLAQRLQDAE 1409
Query: 4798 NELENEKRGKSGAVSHRKKIENQIGELEQQLEVAN----RLKEEYXXXXXXXXXXXXEYQ 4965
+E + +++++N++ +L +E AN RL ++ +Y+
Sbjct: 1410 EHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERANAACARLDKKQKNFDKILAEWKQKYE 1469
Query: 4966 IECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRA 5145
E ++++ +L E + A E + L E L + K A
Sbjct: 1470 ETQAELEASQKESRSLSTELFKMKNAYEESLDHL----ETLKRENKNLQQEISDLTEQIA 1525
Query: 5146 KGGGISSE---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERT 5316
+GG E K+++E + ++ +++ E K + Q++L Q+ ++
Sbjct: 1526 EGGKAIHELEKVKKQIEQEKSEIQAALEEAEASLEHEEGKILRLQLELNQVKSE------ 1579
Query: 5317 LNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAAL------EAKVQYLEDQLNV 5478
+++K + + +++ R++ + ++S + R++ AL E + +E QLN
Sbjct: 1580 IDRKIAEKDEEIDQLKRNHLRIVESMQSTLDAEIRSRNEALRLKKKMEGDLNEMEIQLNH 1639
Query: 5479 EGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDE 5658
+ A + R + L DT +D R E KE + + L+ +++E
Sbjct: 1640 ANRVAAEAQKNLRNTQGVLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEIEELRAA 1699
Query: 5659 MSRERTKHRNVQREADDLLDANEQL 5733
+ + + ++E L+DA+E++
Sbjct: 1700 LEQTERSRKVAEQE---LMDASERV 1721
Score = 139 bits (350), Expect = 8e-31
Identities = 168/900 (18%), Positives = 364/900 (39%), Gaps = 72/900 (8%)
Frame = +1
Query: 3256 KRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVA 3435
K ++ + + EE A +K++ + + + + D++ + A A E
Sbjct: 855 KEMANMKEEFEKTKEELAKSEAKRKELEEKMVKLVQEKNDLQLQVQAEADALADAEERCD 914
Query: 3436 QLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVE 3615
QL K K + K+ E T + +EE+NA ++ +K K +
Sbjct: 915 QLIKTKIQLEAKIKEVTE----RAEDEEEINA--------------ELTAKKRKLEDECS 956
Query: 3616 ELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRK-IHEAHLMEIQ 3792
EL I+ + +++EK+++ + + ++ +E+A L + A + K++K + EAH +
Sbjct: 957 ELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAALDETIAKLTKEKKALQEAHQQTLD 1016
Query: 3793 ANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXX 3972
AE D+ TL + ++D L E+E+ +++R
Sbjct: 1017 DLQAEEDK-VNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLER----------------- 1058
Query: 3973 XXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVN 4152
A L+ ++ ++D + + + L L+K+ Q +++ + E+++
Sbjct: 1059 -------AKRKLEGDLKMSQDTIMDLENDKQQLDEKLKKKDFEISQI--QSKIEDEQALG 1109
Query: 4153 QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSE 4332
QL++ K+ +E L++++E ++ + + + + +ELE+ S LE +
Sbjct: 1110 MQLQKKIKELQARIEELEEEIEAERTSRAKAEKHRADLSRELEEISERLEEAGGATATQI 1169
Query: 4333 KRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNE-VDIMKEHLEESDRVR 4509
KK E++ + R +++A L +A + LR + + L E +D ++ ++ ++ +
Sbjct: 1170 DMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEK 1229
Query: 4510 RSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLE 4689
L+ E+ D SN + K LEK R+LE +L+ ++ + EE + + R RL+
Sbjct: 1230 SELKMEIDDLASNMESVSKAKANLEKMCRTLEDQLSKIKSKEEEHQRMINDLSTQRARLQ 1289
Query: 4690 VTNQALKSESDRAISNKDVEAEEKRRG---LLKQIRDLENELENEKRGKSGAVSHRKKIE 4860
+ E R + KD + RG +QI +L+ LE E + K+ +
Sbjct: 1290 TES----GEYSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKNALAHALQSAR 1345
Query: 4861 NQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIE--------CEEARQAKEDIAALL 5016
+ L +Q E K E +++ + EE +AK+ +A L
Sbjct: 1346 HDCDLLREQYEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1405
Query: 5017 READRKFRAVEAE-------REQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEK 5175
++A+ AV A+ +++L+ E LM ++ + I +E K
Sbjct: 1406 QDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERANAACARLDKKQKNFDKILAEWK 1465
Query: 5176 RRLEAKIAQXXXXXXXXQS-----------------NCELAIDKQRKAQVQLEQITTDLS 5304
++ E A+ +S + E + + Q ++ +T ++
Sbjct: 1466 QKYEETQAELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEISDLTEQIA 1525
Query: 5305 MERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRA----RAQMAALEAK-------- 5448
+ E K+ +E+ + +A + E E+ + R Q+ + K
Sbjct: 1526 EGGKAIHELEKVKKQIEQEKSEIQAALEEAEASLEHEEGKILRLQLELNQVKSEIDRKIA 1585
Query: 5449 ----------------VQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANE 5580
V+ ++ L+ E + + A R +++E LN+ Q R
Sbjct: 1586 EKDEEIDQLKRNHLRIVESMQSTLDAEIRSRNEALRLKKKMEGDLNEMEIQLNHANRVAA 1645
Query: 5581 QAKELLEKSNLKNRNLRRQLDEA-------EDEMSRERTKHRNVQREADDLLDANEQLTR 5739
+A++ L + ++ + LD+A +++++ + +Q E ++L A EQ R
Sbjct: 1646 EAQKNLRNTQGVLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEIEELRAALEQTER 1705
Score = 127 bits (318), Expect = 4e-27
Identities = 139/756 (18%), Positives = 320/756 (41%), Gaps = 45/756 (5%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + E+ +++ + + +R +LE++ + QE+ D+ ++ + AD ++
Sbjct: 854 EKEMANMKEEFEKTKEELAKSEAKRKELEEKMVKLVQEKNDLQLQVQAEADALADAEERC 913
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ + +E L + + DE L + ++ E A ++
Sbjct: 914 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 973
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ K A N+ + L +E AL +E +K +
Sbjct: 974 KE---------------------KHATENKVKNLTEEMAAL----DETIAKLTKEKKALQ 1008
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
A Q + + E+ VN L + + K + V+ L+ LE+ + + + ++K+K++ +L
Sbjct: 1009 EAHQQTLDDLQAEEDKVNT-LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDL 1067
Query: 4279 ---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL 4449
+D+ M+LEN + D + ++K FE + ++ ++AL + +++++ + R+
Sbjct: 1068 KMSQDTIMDLENDK-QQLDEKLKKKDFEISQIQSKIEDEQAL--GMQLQKKIKELQARIE 1124
Query: 4450 SLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFG-----------KNVHELEKAKR 4596
L E++ + ++++ R L +EL++ ++ G K E +K +R
Sbjct: 1125 ELEEEIEAERTSRAKAEKHRADLSRELEEISERLEEAGGATATQIDMNKKREAEFQKMRR 1184
Query: 4597 SL-EAELN-------------DMRVQMEELEDNLQIA------EDARLRLEVTNQALKSE 4716
L EA L D ++ E DNLQ E + L++E+ + A E
Sbjct: 1185 DLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNME 1244
Query: 4717 SDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEV 4896
S +S E+ R L Q+ ++++ E +R + + R +++ + GE +Q+E
Sbjct: 1245 S---VSKAKANLEKMCRTLEDQLSKIKSKEEEHQRMINDLSTQRARLQTESGEYSRQVEE 1301
Query: 4897 ANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA----DRKFRAVEAEREQ 5064
+ L + E + EE +AK +A L+ A D E E+E
Sbjct: 1302 KDALISQLSRGKQAFTQQIEELKRHLEEEIKAKNALAHALQSARHDCDLLREQYEEEQEA 1361
Query: 5065 LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCEL 5244
E L +A + + E K++L ++ + C
Sbjct: 1362 KGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCAS 1421
Query: 5245 AIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARA 5424
+++ Q ++E + D+ + + ++++ ++ ++K K E ++ ++ ++
Sbjct: 1422 LEKTKQRLQNEVEDLMIDVERANAACARLDKKQKNFDKILAEWKQKYEETQAELEA-SQK 1480
Query: 5425 QMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEK 5604
+ +L ++ +++ R + L++ ++D T+Q + +A + +++ ++
Sbjct: 1481 ESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKAIHELEKVKKQ 1540
Query: 5605 SNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ ++ L+EAE + E K +Q E + +
Sbjct: 1541 IEQEKSEIQAALEEAEASLEHEEGKILRLQLELNQV 1576
Score = 101 bits (252), Expect = 2e-19
Identities = 100/485 (20%), Positives = 207/485 (42%), Gaps = 17/485 (3%)
Frame = +1
Query: 2968 QDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYK 3147
++AY+ L ++ D E+ G KA +HELE+ K
Sbjct: 1493 KNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKA-------IHELEK-------VK 1538
Query: 3148 SELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQ 3327
++EQ K ++ A LE+++ L + GK+ L +L + E+ ++ DEE +
Sbjct: 1539 KQIEQEKSEIQAALEEAEASLEHEEGKILRLQLELNQVKSEIDRKIAEKDEE------ID 1592
Query: 3328 KQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMS 3507
+ R+ ++ ++ ++ E +RN+A ++++ L +++ + A Q +
Sbjct: 1593 QLKRNHLRIVESMQSTLDAEIRSRNEALRLKKKMEGDLNEMEIQLNHANRVAAEAQKNLR 1652
Query: 3508 RKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQAD 3687
+ T+ ++ T E ++EQ A R+ L +IE+ + Q E+ + A+
Sbjct: 1653 NTQGVLKDTQIHLDDALRTQED-LKEQVAMVERRANLLQAEIEELRAALEQTERSRKVAE 1711
Query: 3688 QERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRT------------- 3828
QE D ++ + LL + +K E + +IQ+ + ++ + R
Sbjct: 1712 QELMDASERVQLLHTQNTSLINTKKKLETDIAQIQSEMEDTIQEARNAEEKAKKAITDAA 1771
Query: 3829 -LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANIN 4005
+ ++L++ +D HL R+++ + ++Q RL A + +I +
Sbjct: 1772 MMAEELKKEQDTSAHLERMKKNLDQTVKDLQLRLDEAEQLALKGG-------KKQIQKLE 1824
Query: 4006 -RARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQ--QLEELRK 4176
R R+LE E +A ++K AE + K + + E ++EE +L++L
Sbjct: 1825 ARVRELEGEVDA--EQKRSAEAV-----KGVRKYERRVKELTYQSEEDRKNILRLQDLVD 1877
Query: 4177 KNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFES 4356
K V+ ++Q EE+E L +KIQ ELE++ + + + ++F
Sbjct: 1878 KLQMKVKSYKRQAEEAEELSNVNLTKFRKIQHELEEAEERADIAESQVNKLRAKSREFHG 1937
Query: 4357 QMAEE 4371
+ EE
Sbjct: 1938 KKIEE 1942
Score = 98.2 bits (243), Expect = 2e-18
Identities = 114/564 (20%), Positives = 247/564 (43%), Gaps = 32/564 (5%)
Frame = +1
Query: 3046 DHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMG 3225
D +R + +AK +L +L + E+ + + LE+ K++L E+ED +
Sbjct: 1386 DAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERANA 1445
Query: 3226 KVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNK 3405
L+ + D+ L +Y+E A + QK+ R + T + +++ E +
Sbjct: 1446 ACARLDKKQKNFDKILAEWKQKYEETQAELEASQKESRSLSTELFKMKNAYEESLDHLET 1505
Query: 3406 AEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTM---EGK 3576
+ + + ++ + + + L+ + + ++E + + A+E+ + ++ EGK
Sbjct: 1506 LKRENKNLQQEISDLTEQIAEGGKAIHELEKVKKQIEQEKSEIQAALEEAEASLEHEEGK 1565
Query: 3577 I-------EEQKAKFSRQVEELHDQIEQHKKQRSQL-EKQQNQADQERADMAQEIALLQA 3732
I + K++ R++ E ++I+Q K+ ++ E Q+ D E + + L +
Sbjct: 1566 ILRLQLELNQVKSEIDRKIAEKDEEIDQLKRNHLRIVESMQSTLDAEIRSRNEALRLKKK 1625
Query: 3733 SRADIDKKRKIHEAHLMEIQAN-----LAESDEHKRTLIDQLERSRDELDHLNRVREEEE 3897
D+++ MEIQ N AE+ ++ R L+ ++ LD R +E+ +
Sbjct: 1626 MEGDLNE---------MEIQLNHANRVAAEAQKNLRNTQGVLKDTQIHLDDALRTQEDLK 1676
Query: 3898 HAFANMQRR--LATAXXXXXXXXXXXXXXTRLKIAN------INRARQLEDEKNALLDEK 4053
A ++RR L A +R K+A R + L + +L++ K
Sbjct: 1677 EQVAMVERRANLLQAEIEELRAALEQTERSR-KVAEQELMDASERVQLLHTQNTSLINTK 1735
Query: 4054 EEAEGLRAHLEKEIHAARQGAGEARRKAEESVN---QQLEELRKK--NLRDVEHLQKQLE 4218
++ E A ++ E+ Q A A KA++++ EEL+K+ +E ++K L+
Sbjct: 1736 KKLETDIAQIQSEMEDTIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLD 1795
Query: 4219 ESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALL 4398
++ K+ L+ + Q L+ +++ + A R+ E + + AE V+K
Sbjct: 1796 QT--VKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVDAEQKRSAEAVKGVRKYER 1853
Query: 4399 DRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHE 4578
++ + + +L L + VD ++ ++ +R ++ + S N F K HE
Sbjct: 1854 RVKELTYQSEEDRKNILRLQDLVDKLQMKVKS---YKRQAEEAEELSNVNLTKFRKIQHE 1910
Query: 4579 LEKAKRS---LEAELNDMRVQMEE 4641
LE+A+ E+++N +R + E
Sbjct: 1911 LEEAEERADIAESQVNKLRAKSRE 1934
Score = 72.4 bits (176), Expect = 1e-10
Identities = 105/504 (20%), Positives = 201/504 (39%), Gaps = 11/504 (2%)
Frame = +1
Query: 4264 IQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQK---ALLDRDAMSQELRDR 4434
+++E E + EL A ++ E++ K + + ++ VQ AL D + +L
Sbjct: 860 MKEEFEKTKEELAKSEAKRKELEEKMVKLVQEKNDLQLQVQAEADALADAEERCDQLIKT 919
Query: 4435 ETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNK----DDFGKNVHELEKAKRSL 4602
+ ++ + + EV E EE + + +++L+D S DD + ++EK K +
Sbjct: 920 KIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHAT 979
Query: 4603 EAELNDMRVQMEELEDNLQIAEDARLRLEVTNQA----LKSESDRAISNKDVEAEEKRRG 4770
E ++ ++ +M L++ + + L+ +Q L++E D+ N +A+ K
Sbjct: 980 ENKVKNLTEEMAALDETIAKLTKEKKALQEAHQQTLDDLQAEEDKV--NTLTKAKTK--- 1034
Query: 4771 LLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXX 4950
L +Q+ DLE LE EK+ + ++K+E G+L+ + L+ +
Sbjct: 1035 LEQQVDDLEGSLEQEKKLRMDLERAKRKLE---GDLKMSQDTIMDLEND----KQQLDEK 1087
Query: 4951 XXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXX 5130
+ E + + ED AL + +K + ++A E+L E E
Sbjct: 1088 LKKKDFEISQIQSKIEDEQALGMQLQKKIKELQARIEELEEEIEA--------------E 1133
Query: 5131 XXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSME 5310
RAK ++ R LE + +LE+ + +
Sbjct: 1134 RTSRAKAEKHRADLSRELE-------------------------EISERLEEAGGATATQ 1168
Query: 5311 RTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQE 5490
+N+K EAE Q + R +LE A + A AAL K D G++
Sbjct: 1169 IDMNKKREAEFQKMRR----------DLEE-ATLQHEATAAALRKK---HADSTAELGEQ 1214
Query: 5491 KTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRE 5670
R ++LEK ++ + +D +E + NL + ED++S+
Sbjct: 1215 IDNLQRVKQKLEKEKSELKMEIDD-------LASNMESVSKAKANLEKMCRTLEDQLSKI 1267
Query: 5671 RTKHRNVQREADDLLDANEQLTRE 5742
++K QR +DL +L E
Sbjct: 1268 KSKEEEHQRMINDLSTQRARLQTE 1291
Score = 52.8 bits (125), Expect = 1e-04
Identities = 73/332 (21%), Positives = 137/332 (40%), Gaps = 34/332 (10%)
Frame = +1
Query: 4852 KIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADR 5031
KI+ + E + E+AN +KEE+ + ++ +E + L++E +
Sbjct: 843 KIKPLLKSAESEKEMAN-MKEEFEKTKEELAKSEAK-------RKELEEKMVKLVQEKND 894
Query: 5032 KFRAVEAEREQLREANEG---LMQARKQXXXXXXXXXXXRAKGGGISSE---EKRRLEAK 5193
V+AE + L +A E L++ + Q I++E +KR+LE +
Sbjct: 895 LQLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE 954
Query: 5194 IAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEA----EKQSLERS 5361
++ + EL + K K + E +L+ E +T A EK++L+ +
Sbjct: 955 CSELKKDI----DDLELTLAKVEKEKHATENKVKNLTEEMAALDETIAKLTKEKKALQEA 1010
Query: 5362 NRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLE---KR 5532
++ + E + +A+ LE +V LE L E + + RA R+LE K
Sbjct: 1011 HQQTLDDLQAEEDKVNTLTKAK-TKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKM 1069
Query: 5533 LNDTTQQFEDEKRANEQAKELLEKSNL---------------------KNRNLRRQLDEA 5649
DT E++K +Q E L+K + K + L+ +++E
Sbjct: 1070 SQDTIMDLENDK---QQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQARIEEL 1126
Query: 5650 EDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
E+E+ ERT ++ DL E+++ L
Sbjct: 1127 EEEIEAERTSRAKAEKHRADLSRELEEISERL 1158
>gi|23379831|gb|AAM88910.1| fast myosin heavy chain HCIII [Gallus
gallus]
Length = 1940
Score = 1120 bits (2898), Expect = 0.0
Identities = 653/1891 (34%), Positives = 1056/1891 (55%), Gaps = 17/1891 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V E F+ G+I+ + +V V+ + +T+ D V NPPK+DKIEDM+ +T+L
Sbjct: 39 FVVHPKESFVKGTIQSKETGKVTVK-TEGGETLTVKEDQVFSMNPPKYDKIEDMAMMTHL 97
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 98 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVLAYRGKKRQEAPPHIFS 157
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A + K +
Sbjct: 158 IFDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAASGEKKKEEQPGKMQ-- 215
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 216 ---------GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIE 266
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPNV 981
YLLEKSRV Q + ERS+HIFYQI+ E + LL + +Y+F+ IT+P++
Sbjct: 267 TYLLEKSRVTFQLKAERSYHIFYQIMSN-KKPELIDMLLITTNPYDYQFVSQGEITVPSI 325
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
+D +E +T ++ I+GF DE ++I ++ AV+ GNL+F Q+++ +QA V K
Sbjct: 326 NDQEELMATDSATDILGFTPDEKTAIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADK 385
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L+GL +L KA PR+KVG E+V K Q +Q AV A+AKA YE++F W+V RI
Sbjct: 386 AAYLMGLNSADLLKALCYPRVKVGNEYVTKGQTVQQVHNAVGALAKAVYEKMFLWMVVRI 445
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD N EQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 446 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNGLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 504
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H K
Sbjct: 505 KEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNN 564
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P ++++HF++VHYAG VDY+ WL KN DPLNE V+GL Q S+ +A ++
Sbjct: 565 FQKPKPGKGKAEAHFSLVHYAGTVDYNISGWLEKNKDPLNETVIGLYQKSSVKTLALLFA 624
Query: 1870 DAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHE 2049
A G A G + + F+TVS L +E L KLMT LR+T PHFVRCIIPN
Sbjct: 625 SA--GGEPEASGGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 682
Query: 2050 KKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDG 2226
K G + LVL QLRCNGVLEGIRICR+GFP+RV + +F+ RY++L IP+ FID
Sbjct: 683 KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRVLYADFKQRYKVLNASAIPEGQFIDS 742
Query: 2227 KESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSR 2406
K++ K++ ++D+D Y+ G +KVFF+ G+L LEE RD KL LI QA+CRGFL R
Sbjct: 743 KKASEKLLGSIDVDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQARCRGFLMR 802
Query: 2407 RLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRA 2586
Y N +++ +++W W +LF K+KPLL+ ++ E+ +E
Sbjct: 803 VEYPRMVERRESIFCIQYNVRSFMNVKHWPWMKLFFKIKPLLKSAESEKEMANMKEEFEK 862
Query: 2587 TKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYI 2766
TKE L K E +E E+K+ ++ E+ +Q Q+Q E+++ A+ ++ +L +LE
Sbjct: 863 TKEELAKSEAKRKELEEKMVSLLQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAK 922
Query: 2767 VNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXX 2946
+ ++ +R +RK + + +K +
Sbjct: 923 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 982
Query: 2947 XXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDL 3126
+ L E++ KAK +LE Q+ +LE L
Sbjct: 983 TEEMAALDENIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSL 1042
Query: 3127 NRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEES 3306
+E++ + +LE KRKL +L+ + D + + ++L+ +L K+D E+ ++ ++E
Sbjct: 1043 EQEKKLRMDLEGAKRKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQ 1102
Query: 3307 ANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT 3486
A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L++ AT
Sbjct: 1103 ALGMQLQKKIKELQARIEELEEEIEAERTSRAKAEKHRADLSRELEEI-SERLEEAGGAT 1161
Query: 3487 MLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQL 3663
Q D+ +++ E +R +E+ E + K + EL +QI+ ++ + +L
Sbjct: 1162 AAQIDMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKL 1221
Query: 3664 EKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLID-- 3837
EK++++ E D+A + + ++A ++K + E L EI+ + +EH+R + D
Sbjct: 1222 EKEKSELKMEIDDLASNMESVSKAKASLEKTCRALEDQLSEIK---TKEEEHQRMINDLN 1278
Query: 3838 -QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRAR 4014
Q R + E +R EE++ + + R + K A + +
Sbjct: 1279 AQRARLQTESGEYSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKSALAHALQ 1338
Query: 4015 QLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDV 4194
+ + L ++ EE + + L++ + A + R K E Q+ EEL + +
Sbjct: 1339 SARHDCDLLREQYEEDQEAKGELQRALSKANSEVAQWRTKYEADAIQRTEELEEAKKKLA 1398
Query: 4195 EHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMA 4365
+ LQ E E + + ++K+++Q E+ED +++E ++ +K+QK F+ ++
Sbjct: 1399 QRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERANSACAALDKKQKNFDKILS 1458
Query: 4366 EERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSIS 4545
E + ++ + +A +E R T + + N + +HLE R ++ QQE+ D
Sbjct: 1459 EWKQKYEETQTELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNSQQEISDLTE 1518
Query: 4546 NKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDR 4725
+ GK +HELEK K+ +E E ++++ +EE E +L+ E LRL++ +KSE DR
Sbjct: 1519 QIAEGGKAIHELEKVKKQIEQEKSEIQASLEEAEASLEHEEGKILRLQLELNQVKSEIDR 1578
Query: 4726 AISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANR 4905
I+ KD E ++ +R L+ + +++ L+ E R ++ A+ +KK+E + E+E QL ANR
Sbjct: 1579 KIAEKDEEIDQLKRNHLRIVESMQSTLDAEIRSRNEALRLKKKMEGDLNEMEIQLSHANR 1638
Query: 4906 LKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEG 5085
+ E + QI ++A + +ED+ + +R+ ++AE E+LR A E
Sbjct: 1639 VAAEAQKNLRNTQGVLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEIEELRAALEQ 1698
Query: 5086 LMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDK 5256
++RK Q K++LE I+Q A +K
Sbjct: 1699 TERSRKVAEQELMDASERVQLLHTQNTSLINTKKKLETDISQIQSEMEDTIQEARNAEEK 1758
Query: 5257 QRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAA 5436
+KA + +L E+ + E K++L+++ +D + ++ E E A + Q+
Sbjct: 1759 AKKAITDAAMMAEELKKEQDTSAHLERMKKNLDQTVKDLQHRLDEAEQLALKGGKKQIQK 1818
Query: 5437 LEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLK 5616
LEA+V+ LE +++ E + A + R+ E+R+ + T Q E++++ + ++L++K +K
Sbjct: 1819 LEARVRELEGEVDSEQKRSAEAVKGVRKYERRVRELTYQSEEDRKNILRLQDLVDKLQMK 1878
Query: 5617 NRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
++ +RQ +EAE+ + +K R +Q E ++
Sbjct: 1879 VKSYKRQAEEAEELSNVNLSKFRKIQHELEE 1909
Score = 159 bits (402), Expect = 8e-37
Identities = 187/922 (20%), Positives = 385/922 (41%), Gaps = 36/922 (3%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + + +++L + + ELE+ LL E D + + A+ + EE +
Sbjct: 851 KEMANMKEEFEKTKEELAKSEAKRKELEEKMVSLLQEKNDLQLQVQAEADSLADAEERCD 910
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE N L K+ R ++ EL++D++ E
Sbjct: 911 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKDIDD-------LE 962
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E L + +++ +E A + A +Q ++ +
Sbjct: 963 LTLAKVEKEKHATENKVKNLTEEMAALDENIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1022
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK 3753
+ + K K +QV++L +EQ KK R LE + + + + I L+ + +D+
Sbjct: 1023 TLTKAKTKLEQQVDDLEGSLEQEKKLRMDLEGAKRKLEGDLKLAHDSIMDLENDKQQLDE 1082
Query: 3754 KRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLAT 3933
K K + + +IQ+ + E ++ L QL++ EL R+ E EE A R
Sbjct: 1083 KLKKKDFEISQIQSKI----EDEQALGMQLQKKIKELQ--ARIEELEEEIEAERTSRAKA 1136
Query: 3934 AXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQG 4113
RL+ A A Q++ +++K EAE
Sbjct: 1137 EKHRADLSRELEEISERLEEAGGATAAQID------MNKKREAE---------------- 1174
Query: 4114 AGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELED 4284
+ RR EE+ Q LRKK+ L +Q++ + K+++ + K +++ E++D
Sbjct: 1175 FQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDD 1234
Query: 4285 SSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNE 4464
+ +E+V + EK + E Q++E + + + M +L + R L E
Sbjct: 1235 LASNMESVSKAKASLEKTCRALEDQLSEIKTKEE----EHQRMINDLNAQRAR---LQTE 1287
Query: 4465 VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEEL 4644
+EE D + L + Q ++ +++ E KAK +L L R + L
Sbjct: 1288 SGEYSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKSALAHALQSARHDCDLL 1347
Query: 4645 EDNLQIAEDARLRL---------EVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLE 4797
+ + ++A+ L EV K E+D AI + E EE ++ L ++++D E
Sbjct: 1348 REQYEEDQEAKGELQRALSKANSEVAQWRTKYEAD-AIQRTE-ELEEAKKKLAQRLQDAE 1405
Query: 4798 NELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECE 4977
+E + +++++N++ +L +E AN E++ + E
Sbjct: 1406 EHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERANSACAALDKKQKNFDKILSEWKQKYE 1465
Query: 4978 EARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGG 5157
E + E R + ++ E+ + E L + K A+GG
Sbjct: 1466 ETQTELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNSQQEISDLTEQIAEGGK 1525
Query: 5158 ISSE---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQK 5328
E K+++E + ++ +++ E K + Q++L Q+ ++ +++K
Sbjct: 1526 AIHELEKVKKQIEQEKSEIQASLEEAEASLEHEEGKILRLQLELNQVKSE------IDRK 1579
Query: 5329 TEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANR 5508
+ + +++ R++ + ++S + R++ AL K + +E LN + + ANR
Sbjct: 1580 IAEKDEEIDQLKRNHLRIVESMQSTLDAEIRSRNEALRLK-KKMEGDLNEMEIQLSHANR 1638
Query: 5509 AARRLEKR-------LNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSR 5667
A +K L DT +D R E KE + + L+ +++E + +
Sbjct: 1639 VAAEAQKNLRNTQGVLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEIEELRAALEQ 1698
Query: 5668 ERTKHRNVQREADDLLDANEQL 5733
+ ++E L+DA+E++
Sbjct: 1699 TERSRKVAEQE---LMDASERV 1717
Score = 140 bits (353), Expect = 4e-31
Identities = 166/901 (18%), Positives = 364/901 (39%), Gaps = 73/901 (8%)
Frame = +1
Query: 3256 KRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVA 3435
K ++ + + EE A +K++ + ++ + + D++ + A + E
Sbjct: 851 KEMANMKEEFEKTKEELAKSEAKRKELEEKMVSLLQEKNDLQLQVQAEADSLADAEERCD 910
Query: 3436 QLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVE 3615
QL K K + K+ E T + +EE+NA ++ +K K +
Sbjct: 911 QLIKTKIQLEAKIKEVTE----RAEDEEEINA--------------ELTAKKRKLEDECS 952
Query: 3616 ELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQA 3795
EL I+ + +++EK+++ + + ++ +E+A L + A + K++K
Sbjct: 953 ELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAALDENIAKLTKEKK----------- 1001
Query: 3796 NLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXX 3975
A + H++TL D L+ D+++ L + + + E +++ L
Sbjct: 1002 --ALQEAHQQTL-DDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEK------------ 1046
Query: 3976 XTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEE--SV 4149
+L++ R+LE + D + E + L++++ + + K E+ ++
Sbjct: 1047 --KLRMDLEGAKRKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQAL 1104
Query: 4150 NQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDS 4329
QL++ K+ +E L++++E ++ + + + + +ELE+ S LE +
Sbjct: 1105 GMQLQKKIKELQARIEELEEEIEAERTSRAKAEKHRADLSRELEEISERLEEAGGATAAQ 1164
Query: 4330 EKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNE-VDIMKEHLEESDRV 4506
KK E++ + R +++A L +A + LR + + L E +D ++ ++ ++
Sbjct: 1165 IDMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKE 1224
Query: 4507 RRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRL 4686
+ L+ E+ D SN + K LEK R+LE +L++++ + EE + + R RL
Sbjct: 1225 KSELKMEIDDLASNMESVSKAKASLEKTCRALEDQLSEIKTKEEEHQRMINDLNAQRARL 1284
Query: 4687 EVTNQALKSESDRAISNKDVEAEEKRRG---LLKQIRDLENELENEKRGKSGAVSHRKKI 4857
+ + E R + KD + RG +QI +L+ LE E + KS +
Sbjct: 1285 QTES----GEYSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKSALAHALQSA 1340
Query: 4858 ENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIE--------CEEARQAKEDIAAL 5013
+ L +Q E K E +++ + EE +AK+ +A
Sbjct: 1341 RHDCDLLREQYEEDQEAKGELQRALSKANSEVAQWRTKYEADAIQRTEELEEAKKKLAQR 1400
Query: 5014 LREADRKFRAVEAE-------REQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSE- 5169
L++A+ AV A+ +++L+ E LM ++ + I SE
Sbjct: 1401 LQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERANSACAALDKKQKNFDKILSEW 1460
Query: 5170 ----------------EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDL 5301
E R L ++ + + E + + +Q ++ +T +
Sbjct: 1461 KQKYEETQTELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNSQQEISDLTEQI 1520
Query: 5302 SMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRA----RAQMAALEAK------- 5448
+ + E K+ +E+ + +A + E E+ + R Q+ + K
Sbjct: 1521 AEGGKAIHELEKVKKQIEQEKSEIQASLEEAEASLEHEEGKILRLQLELNQVKSEIDRKI 1580
Query: 5449 -----------------VQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRAN 5577
V+ ++ L+ E + + A R +++E LN+ Q R
Sbjct: 1581 AEKDEEIDQLKRNHLRIVESMQSTLDAEIRSRNEALRLKKKMEGDLNEMEIQLSHANRVA 1640
Query: 5578 EQAKELLEKSNLKNRNLRRQLDEA-------EDEMSRERTKHRNVQREADDLLDANEQLT 5736
+A++ L + ++ + LD+A +++++ + +Q E ++L A EQ
Sbjct: 1641 AEAQKNLRNTQGVLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEIEELRAALEQTE 1700
Query: 5737 R 5739
R
Sbjct: 1701 R 1701
Score = 128 bits (321), Expect = 2e-27
Identities = 176/904 (19%), Positives = 363/904 (39%), Gaps = 135/904 (14%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ + ++ +E+D ++ ++KL + E + IQ +++ E +L LQ
Sbjct: 1057 RKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQ 1116
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + +R S R ++E + + +
Sbjct: 1117 ARIEELEEEIE--AERTSRAKAEKHRADLSR--ELEEISERLEEAGGATAAQIDMNKKRE 1172
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K L+
Sbjct: 1173 AEFQKMRRDLEEATLQHEATAAALRKKHADSTAELG---EQIDNLQRVKQKLEKEKSELK 1229
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K+ LE+ R L +L + K E + +LN Q + E
Sbjct: 1230 MEIDDLASNMESVSKAKASLEKTCRALEDQLSEIKTKEEEHQRMINDLNAQRARLQTESG 1289
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ +E+ A ++ + + + I+EL+ +E E A++ + + ++
Sbjct: 1290 EYSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKSALAHALQSARHDCDLLRE 1349
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
+ + LQ +S+ + EV TK + IQ T E +EE K K ++++++ +
Sbjct: 1350 QYEEDQEAKGELQRALSKANSEVAQWRTKYEADAIQRTEE--LEEAKKKLAQRLQDAEEH 1407
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME-------I 3789
+E + + LEK + + E D+ ++ ++ A +DKK+K + L E
Sbjct: 1408 VEAVNAKCASLEKTKQRLQNEVEDLMIDVERANSACAALDKKQKNFDKILSEWKQKYEET 1467
Query: 3790 QANLAESDEHKRTLIDQLERSR----DELDHLNRVREEEEHAFANMQRRLATAXXXXXXX 3957
Q L S + R+L +L + + + LDHL ++ E + N Q+ ++
Sbjct: 1468 QTELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENK----NSQQEISDLTEQIAEG 1523
Query: 3958 XXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKA 4137
++K +Q+E EK+ + EEAE H E +I + + + +
Sbjct: 1524 GKAIHELEKVK-------KQIEQEKSEIQASLEEAEASLEHEEGKILRLQLELNQVKSEI 1576
Query: 4138 EESV---NQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMEL--- 4299
+ + ++++++L++ +LR VE +Q L+ ++ L+ KKK++ +L + ++L
Sbjct: 1577 DRKIAEKDEEIDQLKRNHLRIVESMQSTLDAEIRSRNEALRLKKKMEGDLNEMEIQLSHA 1636
Query: 4300 --------ENVRAS---------HRDS---------------EKRQKKFESQMAEERVAV 4383
+N+R + H D E+R ++++ E R A+
Sbjct: 1637 NRVAAEAQKNLRNTQGVLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEIEELRAAL 1696
Query: 4384 QKALLDRDAMSQELRDRETRV-------LSLLN-----EVDI------MKEHLEESDRVR 4509
++ R QEL D RV SL+N E DI M++ ++E+
Sbjct: 1697 EQTERSRKVAEQELMDASERVQLLHTQNTSLINTKKKLETDISQIQSEMEDTIQEARNAE 1756
Query: 4510 RSLQQELQDSISNKDDFGKNVH---ELEKAKRSLEAELNDMRVQMEELED------NLQI 4662
++ + D+ ++ K LE+ K++L+ + D++ +++E E QI
Sbjct: 1757 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLDQTVKDLQHRLDEAEQLALKGGKKQI 1816
Query: 4663 AE-DARLRL---EVTNQALKSES--------DRAISNKDVEAEEKRRGLLK--------- 4779
+ +AR+R EV ++ +S +R + ++EE R+ +L+
Sbjct: 1817 QKLEARVRELEGEVDSEQKRSAEAVKGVRKYERRVRELTYQSEEDRKNILRLQDLVDKLQ 1876
Query: 4780 ----------------------QIRDLENELE-------------NEKRGKSGAVSHRKK 4854
+ R +++ELE N+ R KS H KK
Sbjct: 1877 MKVKSYKRQAEEAEELSNVNLSKFRKIQHELEEAEERADIAESQVNKLRVKSREF-HSKK 1935
Query: 4855 IENQ 4866
IE +
Sbjct: 1936 IEEE 1939
Score = 124 bits (311), Expect = 3e-26
Identities = 143/760 (18%), Positives = 310/760 (39%), Gaps = 49/760 (6%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + E+ +++ + + +R +LE++ QE+ D+ ++ S AD ++
Sbjct: 850 EKEMANMKEEFEKTKEELAKSEAKRKELEEKMVSLLQEKNDLQLQVQAEADSLADAEERC 909
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ + +E L + + DE L + ++ E A ++
Sbjct: 910 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 969
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ T K+ N+ DE A L ++++A +
Sbjct: 970 KE---------------KHATENKVKNLTEEMAALDENIAKLTKEKKA----------LQ 1004
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
A Q + + E+ VN L + + K + V+ L+ LE+ + + + +K+K++ +L
Sbjct: 1005 EAHQQTLDDLQAEEDKVNT-LTKAKTKLEQQVDDLEGSLEQEKKLRMDLEGAKRKLEGDL 1063
Query: 4279 E---DSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL 4449
+ DS M+LEN + D + ++K FE + ++ ++AL + + +++++ + R+
Sbjct: 1064 KLAHDSIMDLENDK-QQLDEKLKKKDFEISQIQSKIEDEQALGMQ--LQKKIKELQARIE 1120
Query: 4450 SLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRV 4629
L E++ + ++++ R L +EL++ ++ G + EAE MR
Sbjct: 1121 ELEEEIEAERTSRAKAEKHRADLSRELEEISERLEEAGGATAAQIDMNKKREAEFQKMRR 1180
Query: 4630 QMEELE-------------------------DNLQIA------EDARLRLEVTNQALKSE 4716
+EE DNLQ E + L++E+ + A E
Sbjct: 1181 DLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNME 1240
Query: 4717 SDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEV 4896
S +S E+ R L Q+ +++ + E +R + + R +++ + GE +Q+E
Sbjct: 1241 S---VSKAKASLEKTCRALEDQLSEIKTKEEEHQRMINDLNAQRARLQTESGEYSRQVEE 1297
Query: 4897 ANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA----DRKFRAVEAEREQ 5064
+ L + E + EE +AK +A L+ A D E ++E
Sbjct: 1298 KDALISQLSRGKQAFTQQIEELKRHLEEEIKAKSALAHALQSARHDCDLLREQYEEDQEA 1357
Query: 5065 LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCEL 5244
E L +A + + E K++L ++ + C
Sbjct: 1358 KGELQRALSKANSEVAQWRTKYEADAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCAS 1417
Query: 5245 AIDKQRKAQVQLEQITTDLSMERT----LNQKTEAEKQSLERSNRDYKAKITELESGAQS 5412
+++ Q ++E + D+ + L++K + + L + Y+ TELE+ +
Sbjct: 1418 LEKTKQRLQNEVEDLMIDVERANSACAALDKKQKNFDKILSEWKQKYEETQTELEASQKE 1477
Query: 5413 RARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKE 5592
+ K Y E ++E R + ++ ++D T+Q + +A + ++
Sbjct: 1478 SRSLSTELFKMKNAYEESLDHLE-----TLKRENKNSQQEISDLTEQIAEGGKAIHELEK 1532
Query: 5593 LLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ ++ + ++ L+EAE + E K +Q E + +
Sbjct: 1533 VKKQIEQEKSEIQASLEEAEASLEHEEGKILRLQLELNQV 1572
Score = 99.4 bits (246), Expect = 1e-18
Identities = 117/617 (18%), Positives = 257/617 (40%), Gaps = 49/617 (7%)
Frame = +1
Query: 3055 ERAKHGVKAKGRLENQLHELEQDLNRER--------QYKSELEQHKRKLLAELEDSKDHL 3210
E+ + +AKG L+ L + ++ + R Q ELE+ K+KL L+D+++H+
Sbjct: 1349 EQYEEDQEAKGELQRALSKANSEVAQWRTKYEADAIQRTEELEEAKKKLAQRLQDAEEHV 1408
Query: 3211 AEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETER 3390
K L + E++ + + ++ + K+ ++ + E ++ E +
Sbjct: 1409 EAVNAKCASLEKTKQRLQNEVEDLMIDVERANSACAALDKKQKNFDKILSEWKQKYEETQ 1468
Query: 3391 NARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTME 3570
++ R + +L K+K + +D L K E N+ + + + E
Sbjct: 1469 TELEASQKESRSLSTELFKMKNAYEESLDHLETL------KRENKNSQQEISDLTEQIAE 1522
Query: 3571 GKIEEQKAKFSRQVEELHDQIEQHKKQ-RSQLEKQQNQADQERADMAQEIALLQASRADI 3747
G K ++E++ QIEQ K + ++ LE+ + + E + + L +++I
Sbjct: 1523 G------GKAIHELEKVKKQIEQEKSEIQASLEEAEASLEHEEGKILRLQLELNQVKSEI 1576
Query: 3748 DKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVRE---EEEHAFANMQ 3918
D+K + + +++ N E ++ +D RSR+E L + E E +
Sbjct: 1577 DRKIAEKDEEIDQLKRNHLRIVESMQSTLDAEIRSRNEALRLKKKMEGDLNEMEIQLSHA 1636
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKE-----EAEGLRAHL 4083
R+A T++ + + R ++ E+ A+++ + E E LRA L
Sbjct: 1637 NRVAAEAQKNLRNTQGVLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEIEELRAAL 1696
Query: 4084 EKEIHAARQGAGEARRKAEESV------NQQLEELRKKNLRDVEHLQKQLEESEVAKERI 4245
E + +R+ A + A E V N L +KK D+ +Q ++E++ +
Sbjct: 1697 E-QTERSRKVAEQELMDASERVQLLHTQNTSLINTKKKLETDISQIQSEMEDTI---QEA 1752
Query: 4246 LQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMS--- 4416
+++K ++ + D++M E ++ +D+ ++ + + + +Q L + + ++
Sbjct: 1753 RNAEEKAKKAITDAAMMAEELK-KEQDTSAHLERMKKNLDQTVKDLQHRLDEAEQLALKG 1811
Query: 4417 --QELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKA 4590
++++ E RV L EVD ++ E+ + R ++ +++ ++ KN+ L+
Sbjct: 1812 GKKQIQKLEARVRELEGEVDSEQKRSAEAVKGVRKYERRVRELTYQSEEDRKNILRLQDL 1871
Query: 4591 KRSLEAELNDMRVQ---------------------MEELEDNLQIAEDARLRLEVTNQAL 4707
L+ ++ + Q +EE E+ IAE +L V
Sbjct: 1872 VDKLQMKVKSYKRQAEEAEELSNVNLSKFRKIQHELEEAEERADIAESQVNKLRV----- 1926
Query: 4708 KSESDRAISNKDVEAEE 4758
R +K +E EE
Sbjct: 1927 ---KSREFHSKKIEEEE 1940
Score = 71.6 bits (174), Expect = 2e-10
Identities = 98/457 (21%), Positives = 197/457 (42%), Gaps = 40/457 (8%)
Frame = +1
Query: 4492 ESDRVRRSLQQELQDSISNKDDFGKNV---HELEKAKRSLEAELNDMRVQMEELEDNLQI 4662
ES++ ++++E + + K++ K+ ELE+ SL E ND+++Q++ D+L
Sbjct: 848 ESEKEMANMKEEFEKT---KEELAKSEAKRKELEEKMVSLLQEKNDLQLQVQAEADSLAD 904
Query: 4663 AE---DARLRLEVTNQA-LKSESDRAISNKDVEAE--EKRRGLLKQIRDLENELENEKRG 4824
AE D ++ ++ +A +K ++RA +++ AE K+R L + +L+ ++++ +
Sbjct: 905 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 964
Query: 4825 KSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDI 5004
+ + EN++ L +++ +E E + + QA+ED
Sbjct: 965 LAKVEKEKHATENKVKNLTEEMAAL----DENIAKLTKEKKALQEAHQQTLDDLQAEEDK 1020
Query: 5005 AALLREADRKFRA----VEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEE 5172
L +A K +E EQ ++ L A+++ +
Sbjct: 1021 VNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLEGAKRKLEGDLKLAHDSIMD----LEND 1076
Query: 5173 KRRLEAKIAQXXXXXXXXQSNCE----LAIDKQRKA---QVQLEQITTDLSMERTLNQKT 5331
K++L+ K+ + QS E L + Q+K Q ++E++ ++ ERT K
Sbjct: 1077 KQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERTSRAKA 1136
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRARAQM-AALEAKVQYLEDQLNVEGQEKTAANR 5508
E + L R + ++ E +G + A+ M EA+ Q + L +E T +
Sbjct: 1137 EKHRADLSRELEEISERLEE--AGGATAAQIDMNKKREAEFQKMRRDL----EEATLQHE 1190
Query: 5509 A-ARRLEKRLNDTTQQFEDEKRANEQAKELLEK-------------SNLKN-----RNLR 5631
A A L K+ D+T + ++ ++ K+ LEK SN+++ +L
Sbjct: 1191 ATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMESVSKAKASLE 1250
Query: 5632 RQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
+ ED++S +TK QR +DL +L E
Sbjct: 1251 KTCRALEDQLSEIKTKEEEHQRMINDLNAQRARLQTE 1287
Score = 54.3 bits (129), Expect = 4e-05
Identities = 74/349 (21%), Positives = 133/349 (37%), Gaps = 51/349 (14%)
Frame = +1
Query: 4852 KIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADR 5031
KI+ + E + E+AN +KEE+ + ++ +E + +LL+E +
Sbjct: 839 KIKPLLKSAESEKEMAN-MKEEFEKTKEELAKSEAK-------RKELEEKMVSLLQEKND 890
Query: 5032 KFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXX 5211
V+AE + L +A E Q K K +LEAKI +
Sbjct: 891 LQLQVQAEADSLADAEERCDQLIKT----------------------KIQLEAKIKEVTE 928
Query: 5212 XXXXXQS-NCELAIDKQRKAQVQLEQITTDLS-MERTLNQKTEAEKQSLERSNRDYKAKI 5385
+ N EL K+RK + + ++ D+ +E TL K E EK + E ++ ++
Sbjct: 929 RAEDEEEINAELTA-KKRKLEDECSELKKDIDDLELTL-AKVEKEKHATENKVKNLTEEM 986
Query: 5386 TELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDE 5565
L+ + + A EA Q L+D L E + +A +LE++++D E E
Sbjct: 987 AALDENIAKLTKEKKALQEAHQQTLDD-LQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQE 1045
Query: 5566 KRAN----------------------------EQAKELLEKSNL---------------- 5613
K+ +Q E L+K +
Sbjct: 1046 KKLRMDLEGAKRKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALG 1105
Query: 5614 -----KNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
K + L+ +++E E+E+ ERT ++ DL E+++ L
Sbjct: 1106 MQLQKKIKELQARIEELEEEIEAERTSRAKAEKHRADLSRELEEISERL 1154
>gi|24584704|ref|NP_724005.1| CG17927-PA [Drosophila melanogaster]
gi|22946665|gb|AAN10964.1| CG17927-PA [Drosophila melanogaster]
Length = 1962
Score = 1120 bits (2897), Expect = 0.0
Identities = 676/1916 (35%), Positives = 1080/1916 (56%), Gaps = 31/1916 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K CW+PD+ EG+L+G IK D V V L + + +D +Q+ NPPK++K EDMS
Sbjct: 35 KKSCWIPDEKEGYLLGEIKATKGDIVSVGLQGGETR-DLKKDLLQQVNPPKYEKAEDMSN 93
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LTYLN+ASVLHNL+ RYY+ LIYTYSGLFCV INPYK+ P+Y+ + ++GK+R+E+PP
Sbjct: 94 LTYLNDASVLHNLRQRYYNKLIYTYSGLFCVAINPYKRYPVYTNRCAKMYRGKRRNEVPP 153
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIFAI+D AY ML +QS+L TGESGAGKTENTKKVI Y A V +K + AA+
Sbjct: 154 HIFAISDGAYVDMLTNHVNQSMLITGESGAGKTENTKKVIAYFATVGA---SKKTDEAAK 210
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
G LE Q++Q NP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++G
Sbjct: 211 SK-----------GSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFGPTGKLAG 259
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLL-EGVDNYRFLVNRGITL 972
A+IE YLLEK+RV+ Q ERS+HIFYQI+ G K LL + + +Y + +T+
Sbjct: 260 ADIETYLLEKARVISQQSLERSYHIFYQIMSGSVPGVKDICLLTDNIYDYHIVSQGKVTV 319
Query: 973 PNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRV 1152
++DD +EF T + I+GF E + R+ +AV+ +G ++F Q + +QA +
Sbjct: 320 ASIDDAEEFSLTDQAFDILGFTKQEKEDVYRITAAVMHMGGMKFKQRGREEQAEQDGEEE 379
Query: 1153 IQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLV 1332
+V L G EL K L+PRIKVG EFV + +N +Q ++ A+ K ++RLFKWLV
Sbjct: 380 GGRVSKLFGCDTAELYKNLLKPRIKVGNEFVTQGRNVQQVTNSIGALCKGVFDRLFKWLV 439
Query: 1333 TRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQE 1512
+ N++LD T ++ FIG+LDIAGFEIF+ N FEQ+CIN+TNEKLQQ FN+ MF+LEQE
Sbjct: 440 KKCNETLD-TQQKRQHFIGVLDIAGFEIFEYNGFEQLCINFTNEKLQQFFNHHMFVLEQE 498
Query: 1513 EYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NK 1689
EY+REGI+W FIDFG+DL IDLIEKPMG+L++L+EE +FPKA D++F EKL TH K
Sbjct: 499 EYKREGIDWAFIDFGMDLLACIDLIEKPMGILSILEEESMFPKATDQTFSEKLTNTHLGK 558
Query: 1690 HPKFIVPDM----RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVA 1857
F P + +HFA+ HYAG V Y+ WL KN DPLN+ VV + S + +
Sbjct: 559 SAPFQKPKPPKPGQQAAHFAIAHYAGCVSYNITGWLEKNKDPLNDTVVDQFKKSQNKLLI 618
Query: 1858 GIWKDAEFAGICAAEMNETAFGMRSRK-GMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCI 2034
I+ A+ AG E A G R +K G F TVS +KEQL LMTTLR+T PHFVRCI
Sbjct: 619 EIF--ADHAGQSGG--GEQAKGGRGKKGGGFATVSSAYKEQLNSLMTTLRSTQPHFVRCI 674
Query: 2035 IPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKN 2214
IPN K+ G ++++LV+ QL CNGVLEGIRICR+GFPNR+ + +F+ RY+I+ P ++ +
Sbjct: 675 IPNEMKQPGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKMRYKIMCPKLL-QG 733
Query: 2215 FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRG 2394
K++ +I +D+ + YR+G +KVFFR GVL +EE RD +L ++ QA RG
Sbjct: 734 VEKDKKATEIIIKFIDLPEDQYRLGNTKVFFRAGVLGQMEEFRDERLGKIMSWMQAWARG 793
Query: 2395 FLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDD 2574
+LSR+ + N YL+LR W W++L+ KVKPLL V+R +DEI A+ +
Sbjct: 794 YLSRKGFKKLQEQRVALKVVQRNLRKYLQLRTWPWYKLWQKVKPLLNVSRIEDEI-ARLE 852
Query: 2575 ELRATKERLLKMEHDFRENEKKLD-QVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQ 2751
E E L E R+ + L+ +++ E+ + + L E + + +L +
Sbjct: 853 EKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQDYQERNAKLTAQKN 912
Query: 2752 ELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQ 2931
+LE + D+++RL+ ++K + + DK D
Sbjct: 913 DLENQLRDIQERLTQEEDARNQLFQQKKKADQEISGLKKDIEDLELNVQKAEQDKATKDH 972
Query: 2932 XXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHE 3111
+ + +L E++ H K K +LE L E
Sbjct: 973 QIRNLNDEIAHQDELINKLNKEKKMQGETNQKTGEELQAAEDKINHLNKVKAKLEQTLDE 1032
Query: 3112 LEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTR 3291
LE L RE++ + ++E+ KRK+ +L+ +++ +A+ +EL + ++D+EL +
Sbjct: 1033 LEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVADLERNKKELEQTIQRKDKELSSITAK 1092
Query: 3292 YDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDK 3471
++E V Q+Q++++Q I+EL E++E ER AR KAE R ++ +LE++ G+ L++
Sbjct: 1093 LEDEQVVVLKHQRQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEEL-GERLEE 1151
Query: 3472 VDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKK 3648
AT Q +L +++ E++ +R +E+ E + + K + V E+ +Q++Q K
Sbjct: 1152 AGGATSAQIELNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNK 1211
Query: 3649 QRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRT 3828
+++ EK++N+ + D+ + + +A +K K + L E+Q+ L DE RT
Sbjct: 1212 LKAKAEKEKNEYYGQLNDLRAGVDHITNEKAAQEKIAKQLQHTLNEVQSKL---DETNRT 1268
Query: 3829 LIDQLERSRDEL----DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIA 3996
L D + S+ +L L R EE E + + + + +R +
Sbjct: 1269 LND-FDASKKKLSIENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERAT 1327
Query: 3997 NINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHAARQGAGEARRKAEE---SVNQQLE 4164
+ + R LE + + L ++ +EEAEG +A L++++ A A R K E + +++LE
Sbjct: 1328 LLGKFRNLEHDLDNLREQVEEEAEG-KADLQRQLSKANAEAQVWRSKYESDGVARSEELE 1386
Query: 4165 ELRKKNLRDVEHLQKQLEESEVAKERILQ-------SKKKIQQELEDSSMELENVRASHR 4323
E ++K LQ +L E+E E + Q +K+++ E+ED +E++ A
Sbjct: 1387 EAKRK-------LQARLAEAEETIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIAN 1439
Query: 4324 DSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDR 4503
+EK+QK F+ + E ++ V + DA +E R+ T + L + +E LE R
Sbjct: 1440 AAEKKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRR 1499
Query: 4504 VRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLR 4683
++L E++D + + G+N+HE+EKA++ LEAE ++++ +EE E L+ E+ LR
Sbjct: 1500 ENKNLADEVKDLLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLR 1559
Query: 4684 LEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIEN 4863
++ ++ E DR I K+ E E R+ + + ++ LE E +GK+ A+ +KK+E
Sbjct: 1560 AQLELSQVRQEIDRRIQEKEEEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEA 1619
Query: 4864 QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRA 5043
I ELE L+ AN+ E + Q EE ++A++D L ++R+ A
Sbjct: 1620 DINELEIALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANA 1679
Query: 5044 VEAEREQ----LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXX 5211
++ E E+ L +A+ G QA ++ A+ IS+ KR+LE+++
Sbjct: 1680 LQNELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISA-AKRKLESELQTLHS 1738
Query: 5212 XXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITE 5391
+ + + +K +KA V ++ +L E+ Q E +++LE+ ++ + ++ E
Sbjct: 1739 DLDELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDE 1798
Query: 5392 LESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKR 5571
E+ A + + LE +V+ LE++L+ E + A + R+ E+R+ + + Q E++++
Sbjct: 1799 AEANALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRK 1858
Query: 5572 ANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQR---EADDLLDANEQ 5730
+E+ ++L++K K + +RQ++EAE+ + K R Q+ EA++ D EQ
Sbjct: 1859 NHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQ 1914
Score = 155 bits (391), Expect = 1e-35
Identities = 179/950 (18%), Positives = 386/950 (39%), Gaps = 62/950 (6%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDE 3267
RLE + + E+ E + + ELE KLLAE D L+ + G +++
Sbjct: 850 RLEEKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQD---------- 899
Query: 3268 ELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEK 3447
Y E +A +T Q D++ + +++E + E +ARN+ +++ ++
Sbjct: 900 --------YQERNAKLTA---QKNDLENQLRDIQERLTQEEDARNQLFQQKKKADQEISG 948
Query: 3448 VKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+K D+ D + + KD ++ I Q + K+ ++K ++ +
Sbjct: 949 LKKDIEDLELNVQKAEQDKATKDHQIRNLNDEIAH-QDELINKLNKEKKMQGETNQKTGE 1007
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAE 3807
+++ + + + L K + + +Q ++ + + R D++K ++ E L Q +A+
Sbjct: 1008 ELQAAEDKINHLNKVKAKLEQTLDELEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVAD 1067
Query: 3808 SDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL 3987
+ +K+ L ++R EL + E+E+ QR++
Sbjct: 1068 LERNKKELEQTIQRKDKELSSITAKLEDEQVVVLKHQRQIKELQA--------------- 1112
Query: 3988 KIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEE 4167
R +LE+E A + +AE RA L +E+ + GE +A + + Q+E
Sbjct: 1113 ------RIEELEEEVEAERQARAKAEKQRADLAREL----EELGERLEEAGGATSAQIE- 1161
Query: 4168 LRKKNLRDVEHLQKQLEESEVAKERILQS-KKKIQQELEDSSMELENVRASHRDSEKRQK 4344
L KK ++ L++ LEE+ + E L + +KK + + + +++ + +EK +
Sbjct: 1162 LNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNKLKAKAEKEKN 1221
Query: 4345 KFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQ 4524
++ Q+ + R V ++ A + + + + + +++D L + D ++ L
Sbjct: 1222 EYYGQLNDLRAGVDHITNEKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSI 1281
Query: 4525 ELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE--------------LE---DN 4653
E D + ++ V +L K K SL +L D + +E LE DN
Sbjct: 1282 ENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERATLLGKFRNLEHDLDN 1341
Query: 4654 L--QIAEDARLRLEVTNQALKSESDRAISNKDVEA---------EEKRRGLLKQIRDLEN 4800
L Q+ E+A + ++ Q K+ ++ + E+ EE +R L ++ + E
Sbjct: 1342 LREQVEEEAEGKADLQRQLSKANAEAQVWRSKYESDGVARSEELEEAKRKLQARLAEAEE 1401
Query: 4801 ELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEE 4980
+E+ + G ++++ ++ +L+ +++ AN + E++++ ++
Sbjct: 1402 TIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIANAAEKKQKAFDKIIGEWKLKVDD 1461
Query: 4981 ARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGG-G 5157
+ R + ++ E+ +E E + + K +GG
Sbjct: 1462 LAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGRN 1521
Query: 5158 ISSEEK--RRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKT 5331
I EK +RLEA+ + ++ E +K +AQ++L Q+ ++ +R + +K
Sbjct: 1522 IHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEI--DRRIQEKE 1579
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRARA--QMAALEAKVQYLEDQLNVEGQEKTAAN 5505
E + + + R + LE+ A+ +A A LEA + LE L+ + A
Sbjct: 1580 EEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQ 1639
Query: 5506 RAARRLEKRLNDTTQQFEDEKR----------------------------ANEQAKELLE 5601
+ +R +++L D E+E+R EQA
Sbjct: 1640 KNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRR 1699
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
++ + + QL+E + + R ++ E L ++L E N
Sbjct: 1700 QAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDELLNEAKN 1749
Score = 82.4 bits (202), Expect = 1e-13
Identities = 82/418 (19%), Positives = 183/418 (43%), Gaps = 25/418 (5%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L +Q+ E ++++ + + LE K +L A LE+++ L ++ KV +L + +E
Sbjct: 1511 LLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQE 1570
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ ++ +EE N ++ Q +D ++ +E E + +A ++++ A + ++
Sbjct: 1571 IDRRIQEKEEEFENTR------KNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINEL 1624
Query: 3451 KGDVLDKVDEATM-LQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+ LD ++A Q + R +++ + A+E+ Q + EQ R+ L +
Sbjct: 1625 E-IALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDA-REQLGISERRANALQN 1682
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL-- 3801
++E+ + Q ++ + QA+QE AD +++ + A A I ++ E+ L + ++L
Sbjct: 1683 ELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDE 1742
Query: 3802 ----AESDEHKRT--------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
A++ E K L D+L +D ++R+ E +Q RL A
Sbjct: 1743 LLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAEAN 1802
Query: 3946 XXXXXXXXXXXTRLKIANIN------RARQLEDEKNALLDEKEEAE-GLRAHLEKEIHAA 4104
++ + + R + +KN E+ E ++ +++ H
Sbjct: 1803 ALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRKNHER 1862
Query: 4105 RQGAGEARRKAEESVNQQLEELRK---KNLRDVEHLQKQLEESEVAKERILQSKKKIQ 4269
Q + ++ ++ +Q+EE + NL Q++LEE+E + Q+ K +
Sbjct: 1863 MQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQAISKFR 1920
>gi|11321579|ref|NP_003793.1| myosin, heavy polypeptide 13, skeletal
muscle; extraocular muscle myosin heavy chain [Homo
sapiens]
gi|13431717|sp|Q9UKX3|MYHD_HUMAN Myosin heavy chain, skeletal muscle,
extraocular (MyHC-eo)
gi|4808809|gb|AAD29948.1| myosin heavy chain [Homo sapiens]
Length = 1938
Score = 1120 bits (2896), Expect = 0.0
Identities = 654/1896 (34%), Positives = 1059/1896 (55%), Gaps = 18/1896 (0%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K C+V D E ++ G I+ ND+V+V+ +D R +T++ D V NPPKFDKIEDM+
Sbjct: 35 KKACFVADNKEMYVKGMIQTRENDKVIVKTLD-DRMLTLNNDQVFPMNPPKFDKIEDMAM 93
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
+T+L+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y +++ ++GKKR E PP
Sbjct: 94 MTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPP 153
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIF+I+D AY+ ML +R++QSIL TGESGAGKT NTK+VIQY A +A K +
Sbjct: 154 HIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKETQPGK 213
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
G LE Q++QANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++
Sbjct: 214 MQ-----------GTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLAS 262
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRF-LVNRG-IT 969
A+IE YLLEKSRV Q ERS+HIFYQI+ E + LL + + F V++G +T
Sbjct: 263 ADIETYLLEKSRVTFQLSSERSYHIFYQIMSN-KKPELIDLLLISTNPFDFPFVSQGEVT 321
Query: 970 LPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDR 1149
+ ++DD +E +T N++ I+GF+ +E I ++ AV+ GN++F Q+++ +QA
Sbjct: 322 VASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMHYGNMKFKQKQREEQAEPDGTE 381
Query: 1150 VIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWL 1329
V K +L+GL E+ K PR+KVG E+V K QN +Q +V A+AKA YE++F W+
Sbjct: 382 VADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGALAKAVYEKMFLWM 441
Query: 1330 VTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQ 1509
VTRIN+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQ
Sbjct: 442 VTRINQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQ 500
Query: 1510 EEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-N 1686
EEY++EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H
Sbjct: 501 EEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLG 560
Query: 1687 KHPKFIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVA 1857
K F P ++++HF++VHYAG VDY+ WL KN DPLNE VVGL Q S+ ++
Sbjct: 561 KSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSLKLLS 620
Query: 1858 GIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCII 2037
++ + +AG + + G + + F+TVS + +E L KLMT LR+T PHFVRC+I
Sbjct: 621 FLF--SNYAGAETGDSGGSKKGGKKKGSSFQTVSAVFRENLNKLMTNLRSTHPHFVRCLI 678
Query: 2038 PNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-N 2214
PN K G ++ LV+ QLRCNGVLEGIRICR+GFP+R+ + +F+ RY IL IP+
Sbjct: 679 PNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIPEGQ 738
Query: 2215 FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRG 2394
FID K + K++ ++D+D +R G +KVFF+ G+L LEE RD KL L+ + QA CRG
Sbjct: 739 FIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTSTQAVCRG 798
Query: 2395 FLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDD 2574
+L R + N +++ +++W W LF K+KPLL+ + E+ +
Sbjct: 799 YLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKPLLKSAEAEKEMATMKE 858
Query: 2575 ELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQE 2754
+ TKE L + E +E E+K+ ++ E+ +Q Q+Q E+EN + ++ L
Sbjct: 859 DFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKIL 918
Query: 2755 LEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQX 2934
LE V ++ +RL +R + +K +
Sbjct: 919 LEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENK 978
Query: 2935 XXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHEL 3114
++ L E++ +K +LE Q +L
Sbjct: 979 VKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDL 1038
Query: 3115 EQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRY 3294
E L +E++ +++LE+ KRKL +L+ S++ + + + +++ +L K++ EL R
Sbjct: 1039 EGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENEKQQIEEKLKKKEFELSQLQARI 1098
Query: 3295 DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKV 3474
D+E + QK+++++Q I+EL E++E E R K E R ++ +LE++ + L++
Sbjct: 1099 DDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEI-SERLEEA 1157
Query: 3475 DEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQ 3651
AT Q M++K E E +R +E+ E + K + V EL +QI+ ++
Sbjct: 1158 SGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRV 1217
Query: 3652 RSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTL 3831
+ +LEK++++ E DMA I L S+++I++ + E EI+A DE + L
Sbjct: 1218 KQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKA----KDEQQTQL 1273
Query: 3832 IDQLERSRDELD----HLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIAN 3999
I L + L L+ EE+E + + + T+ K A
Sbjct: 1274 IHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAM 1333
Query: 4000 INRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKK 4179
+ + + + L ++ EE + +A L++ + A + + K E Q+ EEL +
Sbjct: 1334 AHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWKTKYETDAIQRTEELEEA 1393
Query: 4180 NLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKF 4350
+ + LQ+ E++E A + + ++K+++Q E+ED +LE + +K+Q+ F
Sbjct: 1394 KKKLAQRLQEAEEKTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNF 1453
Query: 4351 ESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQEL 4530
+ +AE + + ++ + +A +E R T + + N + + + LE R ++LQ+E+
Sbjct: 1454 DKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEI 1513
Query: 4531 QDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALK 4710
D + GKN+ E EK K+ +E E +D++V +EE+E +L+ E LR+++ +K
Sbjct: 1514 SDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVK 1573
Query: 4711 SESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
SE DR + KD E E+ +R + L++ L+ E R ++ A+ +KK+E + E+E QL
Sbjct: 1574 SELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQL 1633
Query: 4891 EVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLR 5070
+NR E + Q+ ++A ++ ED+ L +R+ + E E+++
Sbjct: 1634 GHSNRQMAETQRHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMK 1693
Query: 5071 EANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCE 5241
A E + R+ Q K++LEA IAQ
Sbjct: 1694 VALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESR 1753
Query: 5242 LAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRAR 5421
A +K +KA + +L E+ + E K++LE++ +D + ++ E E A +
Sbjct: 1754 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGK 1813
Query: 5422 AQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLE 5601
Q+ LE +V+ LE++L+VE + A + A + E+++ + T Q E++++ + ++L++
Sbjct: 1814 KQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDRKNILRLQDLVD 1873
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
K K ++ +RQ +EAE++ + + ++ R VQ E ++
Sbjct: 1874 KLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEE 1909
Score = 119 bits (299), Expect = 7e-25
Identities = 143/768 (18%), Positives = 317/768 (40%), Gaps = 45/768 (5%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADID--- 3750
E++ A E +++ + + +R +LE++ QE+ D+ ++ + D +
Sbjct: 850 EKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERC 909
Query: 3751 ----KKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K + + EA + E+ L E +E L+ + D+ L R ++ E ++
Sbjct: 910 EGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVE 969
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ K A N+ + L +E AL EE +K +
Sbjct: 970 KE---------------------KHATENKVKNLSEEMTAL----EENISKLTKEKKSLQ 1004
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
A Q + + E+ VN L ++ K + + L+ LE+ + + + ++K+K++ +L
Sbjct: 1005 EAHQQTLDDLQVEEDKVNG-LIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDL 1063
Query: 4279 ---EDSSMELENVRASHRDSEKRQKKFESQMAEERV--------AVQKALLDRDAMSQEL 4425
++S M+LEN + + K+ K+FE + R+ QK + + A +EL
Sbjct: 1064 KMSQESIMDLENEKQQIEEKLKK-KEFELSQLQARIDDEQVHSLQFQKKIKELQARIEEL 1122
Query: 4426 RDR-----------ETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNV 4572
+ E + L E++ + E LEE+ + +++ + + +F K
Sbjct: 1123 EEEIEAEHTLRAKIEKQRSDLARELEEISERLEEAS---GATSAQIEMNKKREAEFQKMR 1179
Query: 4573 HELEKAKRSLEAELNDMRVQ----MEELEDNLQIAEDARLRLEVTNQALKSESDRAISNK 4740
+LE+A EA +R + + EL + + + + +LE LK E D SN
Sbjct: 1180 RDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASN- 1238
Query: 4741 DVEAEEKRRGLLKQ----IRDLENELENEKRGKSGAV----SHRKKIENQIGELEQQLEV 4896
+EA K + +++ + D +E++ + ++ + + +++ Q GEL ++E
Sbjct: 1239 -IEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEE 1297
Query: 4897 ANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLR----EADRKFRAVEAEREQ 5064
L + E + + EE +AK +A L+ + D E E+E
Sbjct: 1298 KESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEA 1357
Query: 5065 LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCEL 5244
E L +A + + E K++L ++ + S C
Sbjct: 1358 KAELQRALSKANSEVAQWKTKYETDAIQRTEELEEAKKKLAQRLQEAEEKTETANSKCAS 1417
Query: 5245 AIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARA 5424
+++ Q ++E + DL T + ++++ ++ ++K K+ E ++ ++ A+
Sbjct: 1418 LEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEA-AQK 1476
Query: 5425 QMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEK 5604
+ +L ++ + + + R + L++ ++D T+Q + + ++A++ +
Sbjct: 1477 ESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKL 1536
Query: 5605 SNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
+ +L+ L+E E + E +K VQ E L +L R+++
Sbjct: 1537 VEQEKSDLQVALEEVEGSLEHEESKILRVQLE---LSQVKSELDRKVI 1581
Score = 119 bits (298), Expect = 9e-25
Identities = 174/909 (19%), Positives = 366/909 (40%), Gaps = 133/909 (14%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ ++E ++ +E++ ++ E+KL + E + +Q ++ E +S + LQ
Sbjct: 1057 RKLEGDLKMSQESIMDLENEKQQIEEKLKKKEFELSQLQARIDDEQVHSLQFQKKIKELQ 1116
Query: 2740 TRNQELEYIV---NDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXX 2910
R +ELE + + +R ++ +++E + +
Sbjct: 1117 ARIEELEEEIEAEHTLRAKIEKQRSDLA-------RELEEISERLEEASGATSAQIEMNK 1169
Query: 2911 DKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKG 3087
+ Q +A G + +D+ +R K + K K
Sbjct: 1170 KREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELG---EQIDNLQRVKQKLEKEKS 1226
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQ---LMK 3258
L+ ++ ++ ++ + KS +E+ R + + + K ++ + +LN Q L
Sbjct: 1227 ELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQT 1286
Query: 3259 RDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQ 3438
++ EL H R +E+ + ++ + K + + ++EL+ ME E A+N +
Sbjct: 1287 QNGELSH---RVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHD 1343
Query: 3439 LEKVKGDVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQV 3612
+ ++ ++ + LQ +S+ + EV TK + IQ T E +EE K K ++++
Sbjct: 1344 CDLLREQYEEEQEAKAELQRALSKANSEVAQWKTKYETDAIQRTEE--LEEAKKKLAQRL 1401
Query: 3613 EELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME-- 3786
+E ++ E + + LEK + + E D+ +++ + A +DKK++ + L E
Sbjct: 1402 QEAEEKTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWK 1461
Query: 3787 -----IQANLAESDEHKRTLIDQLERSR-------DELDHLNRVREEEEHAFANMQRRLA 3930
QA L + + R+L +L + R D+L+ L R + + +++ ++A
Sbjct: 1462 QKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIA 1521
Query: 3931 TAXXXXXXXXXXXXXXTR----LKIANINRARQLEDEKNALLD----------------- 4047
+ L++A LE E++ +L
Sbjct: 1522 ETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVI 1581
Query: 4048 EKEE------------AEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN--- 4182
EK+E AE L++ L+ EI + R A ++K E +N+ +L N
Sbjct: 1582 EKDEEIEQLKRNSQRAAEALQSVLDAEIRS-RNDALRLKKKMEGDLNEMEIQLGHSNRQM 1640
Query: 4183 ------------------------LRDVEHLQKQL--------------EESEVAKERIL 4248
LR E L++QL EE +VA E+
Sbjct: 1641 AETQRHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTE 1700
Query: 4249 QSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELR 4428
++++ +QEL D+S ++ + + + +KK E+ +A+ + V+ ++ QE R
Sbjct: 1701 RTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSI-------QESR 1753
Query: 4429 DRETRVLSLLNEVDIMKEHLEES-------DRVRRSLQQELQDSISNKDDFG-------- 4563
+ E + + + +M E L++ +R++++L+Q ++D D+
Sbjct: 1754 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGK 1813
Query: 4564 KNVHELEKAKRSLEAELN---------------------DMRVQMEELEDNLQIAEDARL 4680
K + +LE R LE EL+ +M Q EE N+ +D
Sbjct: 1814 KQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDRKNILRLQDLVD 1873
Query: 4681 RLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIE 4860
+L+ ++ K +++ EAEE+ L + R +++ELE A S K+
Sbjct: 1874 KLQAKVKSYKRQAE--------EAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLR 1925
Query: 4861 NQIGELEQQ 4887
+ ++ Q
Sbjct: 1926 AKSRDVGSQ 1934
>gi|24584712|ref|NP_724008.1| CG17927-PK [Drosophila melanogaster]
gi|22946669|gb|AAN10968.1| CG17927-PK [Drosophila melanogaster]
Length = 1936
Score = 1120 bits (2896), Expect = 0.0
Identities = 677/1916 (35%), Positives = 1073/1916 (55%), Gaps = 31/1916 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K CW+PD+ EG+L+G IK D V V L + + +D +Q+ NPPK++K EDMS
Sbjct: 35 KKSCWIPDEKEGYLLGEIKATKGDIVSVGLQGGETR-DLKKDLLQQVNPPKYEKAEDMSN 93
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LTYLN+ASVLHNL+ RYY+ LIYTYSGLFCV INPYK+ P+Y+ + ++GK+R+E+PP
Sbjct: 94 LTYLNDASVLHNLRQRYYNKLIYTYSGLFCVAINPYKRYPVYTNRCAKMYRGKRRNEVPP 153
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIFAI+D AY ML +QS+L TGESGAGKTENTKKVI Y A V +K + AA+
Sbjct: 154 HIFAISDGAYVDMLTNHVNQSMLITGESGAGKTENTKKVIAYFATVGA---SKKTDEAAK 210
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
G LE Q++Q NP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++G
Sbjct: 211 SK-----------GSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFGPTGKLAG 259
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSE-YLLEGVDNYRFLVNRGITL 972
A+IE YLLEK+RV+ Q ERS+HIFYQI+ G K +L + + +Y + +T+
Sbjct: 260 ADIETYLLEKARVISQQSLERSYHIFYQIMSGSVPGVKEMCFLSDNIYDYYNVSQGKVTV 319
Query: 973 PNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRV 1152
PN+DD +EF + I+GF E + R+ +AV+ +G ++F Q + +QA +
Sbjct: 320 PNMDDGEEFQLADQAFDILGFTKQEKEDVYRITAAVMHMGGMKFKQRGREEQAEQDGEEE 379
Query: 1153 IQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLV 1332
+V L G EL K L+PRIKVG EFV + +N +Q ++ A+ K ++RLFKWLV
Sbjct: 380 GGRVSKLFGCDTAELYKNLLKPRIKVGNEFVTQGRNVQQVTNSIGALCKGVFDRLFKWLV 439
Query: 1333 TRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQE 1512
+ N++LD T ++ FIG+LDIAGFEIF+ N FEQ+CIN+TNEKLQQ FN+ MF++EQE
Sbjct: 440 KKCNETLD-TQQKRQHFIGVLDIAGFEIFEYNGFEQLCINFTNEKLQQFFNHIMFVMEQE 498
Query: 1513 EYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NK 1689
EY++EGI WDFIDFG+DL IDLIEKPMG+L++L+EE +FPKA D++F EKL TH K
Sbjct: 499 EYKKEGINWDFIDFGMDLLACIDLIEKPMGILSILEEESMFPKATDQTFSEKLTNTHLGK 558
Query: 1690 HPKFIVPDM----RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVA 1857
F P + +HFA+ HYAG V Y+ WL KN DPLN+ VV + S + +
Sbjct: 559 SAPFQKPKPPKPGQQAAHFAIAHYAGCVSYNITGWLEKNKDPLNDTVVDQFKKSQNKLLI 618
Query: 1858 GIWKDAEFAGICAAEMNETAFGMRSRK-GMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCI 2034
I+ A+ AG E A G R +K G F TVS +KEQL LMTTLR+T PHFVRCI
Sbjct: 619 EIF--ADHAGQSGG--GEQAKGGRGKKGGGFATVSSAYKEQLNSLMTTLRSTQPHFVRCI 674
Query: 2035 IPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKN 2214
IPN K+ G ++++LV+ QL CNGVLEGIRICR+GFPNR+ + +F+ RY IL P ++
Sbjct: 675 IPNEMKQPGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKMRYMILAPAIMAAE 734
Query: 2215 FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRG 2394
+ K + K + A+ +D ++YRIG +KVFFR GVL +EE RD +L ++ QA RG
Sbjct: 735 KV-AKNAAGKCLEAVGLDPDMYRIGHTKVFFRAGVLGQMEEFRDERLGKIMSWMQAWARG 793
Query: 2395 FLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDD 2574
+LSR+ + N YL+LR W W++L+ KVKPLL V+R +DEI A+ +
Sbjct: 794 YLSRKGFKKLQEQRVALKVVQRNLRKYLQLRTWPWYKLWQKVKPLLNVSRIEDEI-ARLE 852
Query: 2575 ELRATKERLLKMEHDFRENEKKLD-QVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQ 2751
E E L E R+ + L+ +++ E+ + + L E + + +L +
Sbjct: 853 EKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQDYQERNAKLTAQKN 912
Query: 2752 ELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQ 2931
+LE + D+++RL+ ++K + + DK D
Sbjct: 913 DLENQLRDIQERLTQEEDARNQLFQQKKKADQEISGLKKDIEDLELNVQKAEQDKATKDH 972
Query: 2932 XXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHE 3111
+ + +L E++ H K K +LE L E
Sbjct: 973 QIRNLNDEIAHQDELINKLNKEKKMQGETNQKTGEELQAAEDKINHLNKVKAKLEQTLDE 1032
Query: 3112 LEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTR 3291
LE L RE++ + ++E+ KRK+ +L+ +++ +A+ +EL + ++D+EL +
Sbjct: 1033 LEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVADLERNKKELEQTIQRKDKELSSITAK 1092
Query: 3292 YDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDK 3471
++E V Q+Q++++Q I+EL E++E ER AR KAE R ++ +LE++ G+ L++
Sbjct: 1093 LEDEQVVVLKHQRQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEEL-GERLEE 1151
Query: 3472 VDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKK 3648
AT Q +L +++ E++ +R +E+ E + + K + V E+ +Q++Q K
Sbjct: 1152 AGGATSAQIELNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNK 1211
Query: 3649 QRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRT 3828
+++ E + E L +A +K K + L E+Q+ L DE RT
Sbjct: 1212 LKAKAEHDRQTCHNELNQTRTACDQLGRDKAAQEKIAKQLQHTLNEVQSKL---DETNRT 1268
Query: 3829 LIDQLERSRDEL----DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIA 3996
L D + S+ +L L R EE E + + + + +R +
Sbjct: 1269 LND-FDASKKKLSIENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERAT 1327
Query: 3997 NINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHAARQGAGEARRKAEE---SVNQQLE 4164
+ + R LE + + L ++ +EEAEG +A L++++ A A R K E + +++LE
Sbjct: 1328 LLGKFRNLEHDLDNLREQVEEEAEG-KADLQRQLSKANAEAQVWRSKYESDGVARSEELE 1386
Query: 4165 ELRKKNLRDVEHLQKQLEESEVAKERILQ-------SKKKIQQELEDSSMELENVRASHR 4323
E ++K LQ +L E+E E + Q +K+++ E+ED +E++ A
Sbjct: 1387 EAKRK-------LQARLAEAEETIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIAN 1439
Query: 4324 DSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDR 4503
+EK+QK F+ + E ++ V + DA +E R+ T + L + +E LE R
Sbjct: 1440 AAEKKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRR 1499
Query: 4504 VRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLR 4683
++L E++D + + G+N+HE+EKA++ LEAE ++++ +EE E L+ E+ LR
Sbjct: 1500 ENKNLADEVKDLLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLR 1559
Query: 4684 LEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIEN 4863
++ ++ E DR I K+ E E R+ + + ++ LE E +GK+ A+ +KK+E
Sbjct: 1560 AQLELSQVRQEIDRRIQEKEEEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEA 1619
Query: 4864 QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRA 5043
I ELE L+ AN+ E + Q EE ++A++D L ++R+ A
Sbjct: 1620 DINELEIALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANA 1679
Query: 5044 VEAEREQ----LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXX 5211
++ E E+ L +A+ G QA ++ A+ IS+ KR+LE+++
Sbjct: 1680 LQNELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISA-AKRKLESELQTLHS 1738
Query: 5212 XXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITE 5391
+ + + +K +KA V ++ +L E+ Q E +++LE+ ++ + ++ E
Sbjct: 1739 DLDELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDE 1798
Query: 5392 LESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKR 5571
E+ A + + LE +V+ LE++L+ E + A + R+ E+R+ + + Q E++++
Sbjct: 1799 AEANALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRK 1858
Query: 5572 ANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQR---EADDLLDANEQ 5730
+E+ ++L++K K + +RQ++EAE+ + K R Q+ EA++ D EQ
Sbjct: 1859 NHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQ 1914
Score = 151 bits (382), Expect = 2e-34
Identities = 178/950 (18%), Positives = 386/950 (39%), Gaps = 62/950 (6%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDE 3267
RLE + + E+ E + + ELE KLLAE D L+ + G +++
Sbjct: 850 RLEEKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQD---------- 899
Query: 3268 ELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEK 3447
Y E +A +T Q D++ + +++E + E +ARN+ +++ ++
Sbjct: 900 --------YQERNAKLTA---QKNDLENQLRDIQERLTQEEDARNQLFQQKKKADQEISG 948
Query: 3448 VKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+K D+ D + + KD ++ I Q + K+ ++K ++ +
Sbjct: 949 LKKDIEDLELNVQKAEQDKATKDHQIRNLNDEIAH-QDELINKLNKEKKMQGETNQKTGE 1007
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAE 3807
+++ + + + L K + + +Q ++ + + R D++K ++ E L Q +A+
Sbjct: 1008 ELQAAEDKINHLNKVKAKLEQTLDELEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVAD 1067
Query: 3808 SDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL 3987
+ +K+ L ++R EL + E+E+ QR++
Sbjct: 1068 LERNKKELEQTIQRKDKELSSITAKLEDEQVVVLKHQRQIKELQA--------------- 1112
Query: 3988 KIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEE 4167
R +LE+E A + +AE RA L +E+ + GE +A + + Q+E
Sbjct: 1113 ------RIEELEEEVEAERQARAKAEKQRADLAREL----EELGERLEEAGGATSAQIE- 1161
Query: 4168 LRKKNLRDVEHLQKQLEESEVAKERILQS-KKKIQQELEDSSMELENVRASHRDSEKRQK 4344
L KK ++ L++ LEE+ + E L + +KK + + + +++ + +E ++
Sbjct: 1162 LNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNKLKAKAEHDRQ 1221
Query: 4345 KFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQ 4524
+++ + R A + D+ A + + + + + +++D L + D ++ L
Sbjct: 1222 TCHNELNQTRTACDQLGRDKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSI 1281
Query: 4525 ELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE--------------LE---DN 4653
E D + ++ V +L K K SL +L D + +E LE DN
Sbjct: 1282 ENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERATLLGKFRNLEHDLDN 1341
Query: 4654 L--QIAEDARLRLEVTNQALKSESDRAISNKDVEA---------EEKRRGLLKQIRDLEN 4800
L Q+ E+A + ++ Q K+ ++ + E+ EE +R L ++ + E
Sbjct: 1342 LREQVEEEAEGKADLQRQLSKANAEAQVWRSKYESDGVARSEELEEAKRKLQARLAEAEE 1401
Query: 4801 ELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEE 4980
+E+ + G ++++ ++ +L+ +++ AN + E++++ ++
Sbjct: 1402 TIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIANAAEKKQKAFDKIIGEWKLKVDD 1461
Query: 4981 ARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGG-G 5157
+ R + ++ E+ +E E + + K +GG
Sbjct: 1462 LAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGRN 1521
Query: 5158 ISSEEK--RRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKT 5331
I EK +RLEA+ + ++ E +K +AQ++L Q+ ++ +R + +K
Sbjct: 1522 IHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEI--DRRIQEKE 1579
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRARA--QMAALEAKVQYLEDQLNVEGQEKTAAN 5505
E + + + R + LE+ A+ +A A LEA + LE L+ + A
Sbjct: 1580 EEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQ 1639
Query: 5506 RAARRLEKRLNDTTQQFEDEKR----------------------------ANEQAKELLE 5601
+ +R +++L D E+E+R EQA
Sbjct: 1640 KNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRR 1699
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
++ + + QL+E + + R ++ E L ++L E N
Sbjct: 1700 QAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDELLNEAKN 1749
Score = 82.4 bits (202), Expect = 1e-13
Identities = 82/418 (19%), Positives = 183/418 (43%), Gaps = 25/418 (5%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L +Q+ E ++++ + + LE K +L A LE+++ L ++ KV +L + +E
Sbjct: 1511 LLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQE 1570
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ ++ +EE N ++ Q +D ++ +E E + +A ++++ A + ++
Sbjct: 1571 IDRRIQEKEEEFENTR------KNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINEL 1624
Query: 3451 KGDVLDKVDEATM-LQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+ LD ++A Q + R +++ + A+E+ Q + EQ R+ L +
Sbjct: 1625 E-IALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDA-REQLGISERRANALQN 1682
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL-- 3801
++E+ + Q ++ + QA+QE AD +++ + A A I ++ E+ L + ++L
Sbjct: 1683 ELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDE 1742
Query: 3802 ----AESDEHKRT--------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
A++ E K L D+L +D ++R+ E +Q RL A
Sbjct: 1743 LLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAEAN 1802
Query: 3946 XXXXXXXXXXXTRLKIANIN------RARQLEDEKNALLDEKEEAE-GLRAHLEKEIHAA 4104
++ + + R + +KN E+ E ++ +++ H
Sbjct: 1803 ALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRKNHER 1862
Query: 4105 RQGAGEARRKAEESVNQQLEELRK---KNLRDVEHLQKQLEESEVAKERILQSKKKIQ 4269
Q + ++ ++ +Q+EE + NL Q++LEE+E + Q+ K +
Sbjct: 1863 MQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQAISKFR 1920
>gi|34870880|ref|XP_340818.1| myosin, heavy polypeptide 4 [Rattus
norvegicus]
Length = 1959
Score = 1119 bits (2895), Expect = 0.0
Identities = 662/1918 (34%), Positives = 1070/1918 (55%), Gaps = 44/1918 (2%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V + E F+ G+I+ + +V V+ + +T+ D + NPPK+DKIEDM+ +T+L
Sbjct: 39 FVAEPKESFVKGTIQSKDAGKVTVK-TEAGATLTVKEDQIFPMNPPKYDKIEDMAMMTHL 97
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 98 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVAAYRGKKRQEAPPHIFS 157
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVA--GATRNKSLNAAAQQN 621
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A G + + + + Q
Sbjct: 158 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQ- 216
Query: 622 IVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGAN 801
G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+
Sbjct: 217 -----------GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASAD 265
Query: 802 IEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLP 975
IE YLLEKSRV Q + ERS+HIFYQI E E LL + +Y F+ I++
Sbjct: 266 IETYLLEKSRVTFQLKAERSYHIFYQITSN-KKPELIEMLLITTNPYDYPFVSQGEISVA 324
Query: 976 NVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVI 1155
++DD +E +T +++ I+GF +DE SI ++ AV+ GN++F Q+++ +QA V
Sbjct: 325 SIDDQEELMATDSAIDILGFTNDEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVA 384
Query: 1156 QKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVT 1335
K +L GL +L KA PR+KVG E+V K Q EQ AV A+AKA YE++F W+VT
Sbjct: 385 DKAAYLQGLNSADLLKALCYPRVKVGNEYVTKGQTVEQVTNAVGALAKAMYEKMFLWMVT 444
Query: 1336 RINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEE 1515
RIN+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEE
Sbjct: 445 RINQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEE 503
Query: 1516 YQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKH 1692
Y++EGIEW FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL + H K
Sbjct: 504 YKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKS 563
Query: 1693 PKFIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGI 1863
F P + ++++HF+++HYAG VDY+ WL KN DPLNE VVGL Q S+ +A +
Sbjct: 564 ANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNETVVGLYQKSSMKTLAYL 623
Query: 1864 WKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPN 2043
+ A+ A A+ G + + F+TVS L +E L KLMT LR+T PHFVRCIIPN
Sbjct: 624 FSGAQTAEAEASSGGAAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPN 683
Query: 2044 HEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFI 2220
K G + LVL QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L IP+ +I
Sbjct: 684 ETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQYI 743
Query: 2221 DGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFL 2400
D K++ K++ ++DID Y+ G +KVFF+ G+L LEE RD KL LI QA CRGFL
Sbjct: 744 DSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQAMCRGFL 803
Query: 2401 SRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDEL 2580
+R Y N A++ +++W W +LF K+KPLL+ T+ E+ +E
Sbjct: 804 ARVEYQKMVERRESIFCIQYNIRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEF 863
Query: 2581 RATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELE 2760
+ TK+ L K E +E E+K+ ++ E+ +Q Q+Q E+E A+ ++ +L +LE
Sbjct: 864 QKTKDELAKSEAKRKELEEKMVSLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLE 923
Query: 2761 YIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXX 2940
+ ++ +R +RK + + +K +
Sbjct: 924 AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 983
Query: 2941 XXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQ 3120
+ L E++ KAK +LE Q+ +LE
Sbjct: 984 NLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEG 1043
Query: 3121 DLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDE 3300
L +E++ + +LE+ KRKL +L+ +++ + + + ++L+ +L K++ E+ + ++ ++
Sbjct: 1044 SLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDERLKKKEFEMSNLQSKIED 1103
Query: 3301 ESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDE 3480
E A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L++
Sbjct: 1104 EQAIGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEI-SERLEEAGG 1162
Query: 3481 ATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRS 3657
AT Q M++K E E +R +E+ E + K + V EL +QI+ ++ +
Sbjct: 1163 ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQ 1222
Query: 3658 QLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLID 3837
+LEK++++ E D+A + + ++ +++K + E + E+++ +E ++ LI+
Sbjct: 1223 KLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQVSELKS----KEEEQQRLIN 1278
Query: 3838 QLERSRDELD---------HLNRVREE--EEHAFANMQRRLATAXXXXXXXXXXXXXXTR 3984
L R L L R+E + A++ + A
Sbjct: 1279 DLTTQRGRLQTESGNSPSPMLFEHRDEVVKNKCAADLDEKEALVSQLSRGKQAFTQQIEE 1338
Query: 3985 LKIANINRARQLEDE---KNALL--------------DEKEEAEGLRAHLEKEIHAARQG 4113
LK RQLE+E KNAL ++ EE + +A L++ + A
Sbjct: 1339 LK-------RQLEEEVKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANSE 1391
Query: 4114 AGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELED 4284
+ R K E Q+ EEL + + + LQ E E + + ++K+++Q E+ED
Sbjct: 1392 VAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVED 1451
Query: 4285 SSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNE 4464
+++E A+ +K+Q+ F+ +AE + ++ + +A +E R T + + N
Sbjct: 1452 LMLDVERTNAACAALDKKQRNFDKILAEWKQKYEETHAELEASQKEARSLGTELFKMKNA 1511
Query: 4465 VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEEL 4644
+ + LE R ++LQQE+ D + GK +HELEK K+ +E E +++ +EE
Sbjct: 1512 YEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEA 1571
Query: 4645 EDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRG 4824
E +L+ E LR+++ +KSE DR I+ KD E ++ +R ++ + +++ L+ E R
Sbjct: 1572 EASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKRNHIRVVESMQSTLDAEIRS 1631
Query: 4825 KSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDI 5004
++ A+ +KK+E + E+E QL ANR+ E + Q+ ++A + +ED+
Sbjct: 1632 RNDAIRIKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQLHLDDALRGQEDL 1691
Query: 5005 AALLREADRKFRAVEAEREQLREANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEK 5175
L +R+ ++AE E+LR E ++RK Q K
Sbjct: 1692 KEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTK 1751
Query: 5176 RRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLE 5355
++LE I+Q A +K +KA + +L E+ + E K+++E
Sbjct: 1752 KKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 1811
Query: 5356 RSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRL 5535
++ +D + ++ E E A + Q+ LEA+V+ LE ++ E + A + R+ E+R+
Sbjct: 1812 QTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERRV 1871
Query: 5536 NDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+ T Q E++++ + ++L++K K ++ +RQ +EAE++ + +K R +Q E ++
Sbjct: 1872 KELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLSKFRKLQHELEE 1929
Score = 108 bits (269), Expect = 2e-21
Identities = 138/779 (17%), Positives = 313/779 (39%), Gaps = 68/779 (8%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + ++ D++ + + +R +LE++ +E+ D+ ++ AD ++
Sbjct: 853 EKEMATMKEEFQKTKDELAKSEAKRKELEEKMVSLLKEKNDLQLQVQAEAEGLADAEERC 912
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ + +E L + + DE L + ++ E A ++
Sbjct: 913 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 972
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ K A N+ + L +E L +E +K +
Sbjct: 973 KE---------------------KHATENKVKNLTEEMAGL----DETIAKLTKEKKALQ 1007
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
A Q + + E+ VN L + + K + V+ L+ LE+ + + + ++K+K++ +L
Sbjct: 1008 EAHQQTLDDLQAEEDKVNT-LTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDL 1066
Query: 4279 ---EDSSMELENVRASHRDSEKRQKKFE-----SQMAEER---VAVQKALLDRDAMSQEL 4425
++S M++EN + D ++K+FE S++ +E+ + +QK + + A +EL
Sbjct: 1067 KLAQESIMDIENEK-QQLDERLKKKEFEMSNLQSKIEDEQAIGIQLQKKIKELQARIEEL 1125
Query: 4426 RDR-----------ETRVLSLLNEVDIMKEHLEES------------------DRVRRSL 4518
+ E + L E++ + E LEE+ ++RR L
Sbjct: 1126 EEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDL 1185
Query: 4519 QQ--------------ELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNL 4656
++ + DS++ + G+ + L++ K+ LE E ++M++++++L N+
Sbjct: 1186 EEATLQHEATAATLRKKHADSVA---ELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNV 1242
Query: 4657 QIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGA 4836
+ A+ LE + L+ + S EE+++ L+ + L+ E
Sbjct: 1243 ETVSKAKGNLEKMCRTLEDQVSELKSK-----EEEQQRLINDLTTQRGRLQTESGNSPSP 1297
Query: 4837 VSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALL 5016
+ + E + L+ L + E + + EE +AK +A L
Sbjct: 1298 MLFEHRDEVVKNKCAADLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEVKAKNALAHAL 1357
Query: 5017 R----EADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRL 5184
+ + D E E+E E L +A + + E K++L
Sbjct: 1358 QSSRHDCDLLREQYEEEQESKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 1417
Query: 5185 EAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSN 5364
++ + C +++ Q ++E + D+ + ++++ ++
Sbjct: 1418 AQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKIL 1477
Query: 5365 RDYKAKITELES---GAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRL 5535
++K K E + +Q AR+ L E+ L+ + R + L++ +
Sbjct: 1478 AEWKQKYEETHAELEASQKEARSLGTELFKMKNAYEESLD----QLETLKRENKNLQQEI 1533
Query: 5536 NDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+D T+Q + + + +++ ++ + L+ L+EAE + E K +Q E + +
Sbjct: 1534 SDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQV 1592
Score = 105 bits (263), Expect = 1e-20
Identities = 166/905 (18%), Positives = 353/905 (38%), Gaps = 128/905 (14%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ +E ++ +E++ ++ +++L + E + +Q +++ E +L LQ
Sbjct: 1060 RKLEGDLKLAQESIMDIENEKQQLDERLKKKEFEMSNLQSKIEDEQAIGIQLQKKIKELQ 1119
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + +R S R ++E + + +
Sbjct: 1120 ARIEELEEEIE--AERASRAKAEKQRSDLSR--ELEEISERLEEAGGATSAQIEMNKKRE 1175
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K ++
Sbjct: 1176 AEFQKMRRDLEEATLQHEATAATLRKKHADSVAELG---EQIDNLQRVKQKLEKEKSEMK 1232
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMK------ 3258
++ +L ++ + K LE+ R L ++ + K E+ + +L Q +
Sbjct: 1233 MEIDDLASNVETVSKAKGNLEKMCRTLEDQVSELKSKEEEQQRLINDLTTQRGRLQTESG 1292
Query: 3259 ----------RDEELQHQLTR-YDEESANVTLMQKQMRDMQTTIDELREDMETERNARNK 3405
RDE ++++ DE+ A V+ + + + I+EL+ +E E A+N
Sbjct: 1293 NSPSPMLFEHRDEVVKNKCAADLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEVKAKNA 1352
Query: 3406 AEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKI 3579
+ + ++ ++ + LQ +S+ + EV TK + IQ T E +
Sbjct: 1353 LAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANSEVAQWRTKYETDAIQRTEE--L 1410
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKR 3759
EE K K +++++ + +E + + LEK + + E D+ ++ A+ A +DKK+
Sbjct: 1411 EEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQ 1470
Query: 3760 KIHEAHLME-------IQANLAESDEHKRTLIDQL-------ERSRDELDHLNRVREEEE 3897
+ + L E A L S + R+L +L E S D+L+ L R + +
Sbjct: 1471 RNFDKILAEWKQKYEETHAELEASQKEARSLGTELFKMKNAYEESLDQLETLKRENKNLQ 1530
Query: 3898 HAFANMQRRLATAXXXXXXXXXXXXXXTR----LKIANINRARQLEDEKNALLDEKEEAE 4065
+++ ++A + L+ A LE E+ +L + E
Sbjct: 1531 QEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELN 1590
Query: 4066 GLRAHLEKEIHAARQGAGEARR---KAEESVNQQLE----------ELRKKNLRDVEHLQ 4206
+++ ++++I + + +R + ES+ L+ ++KK D+ ++
Sbjct: 1591 QVKSEIDRKIAEKDEEIDQLKRNHIRVVESMQSTLDAEIRSRNDAIRIKKKMEGDLNEME 1650
Query: 4207 KQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDS-------EKRQKKFESQMA 4365
QL + L++ + Q L+D+ + L++ D E+R ++++
Sbjct: 1651 IQLNHANRMAAEALRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAMVERRANLLQAEIE 1710
Query: 4366 EERVAVQKALLDRDAMSQELRDRETRV-------LSLLN-----EVDI------MKEHLE 4491
E R +++ R QEL D RV SL+N E DI M++ ++
Sbjct: 1711 ELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQ 1770
Query: 4492 ESDRVRRSLQQELQDSISNKDDFGKNVH---ELEKAKRSLEAELNDMRVQMEELED---- 4650
E+ ++ + D+ ++ K LE+ K+++E + D++++++E E
Sbjct: 1771 EARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALK 1830
Query: 4651 --NLQIAE-DARLR------------------------LEVTNQALKSESDR-------- 4725
QI + +AR+R V ++E DR
Sbjct: 1831 GGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQD 1890
Query: 4726 ----------AISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGE 4875
+ + EAEE+ L + R L++ELE + A S K+ + E
Sbjct: 1891 LVDKLQAKVKSYKRQAEEAEEQSNTNLSKFRKLQHELEEAEERADIAESQVNKLRVKSRE 1950
Query: 4876 LEQQL 4890
+ ++
Sbjct: 1951 VHTKV 1955
>gi|24584692|ref|NP_723999.1| CG17927-PC [Drosophila melanogaster]
gi|22946659|gb|AAN10959.1| CG17927-PC [Drosophila melanogaster]
Length = 1962
Score = 1119 bits (2894), Expect = 0.0
Identities = 677/1916 (35%), Positives = 1078/1916 (55%), Gaps = 31/1916 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K CW+PD+ EG+L+G IK D V V L + I + V+K NPPKF+KIEDM++
Sbjct: 35 KKSCWIPDEKEGYLLGEIKATKGDIVSVGLQGGEVR-DIKSEKVEKVNPPKFEKIEDMAD 93
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
+T LN VLHNL+ RYY+ LIYTYSGLFCV INPYK+ P+Y+ + ++GK+R+E+PP
Sbjct: 94 MTVLNTPCVLHNLRQRYYAKLIYTYSGLFCVAINPYKRYPVYTNRCAKMYRGKRRNEVPP 153
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIFAI+D AY ML +QS+L TGESGAGKTENTKKVI Y A V +K + AA+
Sbjct: 154 HIFAISDGAYVDMLTNHVNQSMLITGESGAGKTENTKKVIAYFATVGA---SKKTDEAAK 210
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
G LE Q++Q NP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++G
Sbjct: 211 SK-----------GSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFGPTGKLAG 259
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLL-EGVDNYRFLVNRGITL 972
A+IE YLLEK+RV+ Q ERS+HIFYQI+ G K LL + + +Y + +T+
Sbjct: 260 ADIETYLLEKARVISQQSLERSYHIFYQIMSGSVPGVKDICLLTDNIYDYHIVSQGKVTV 319
Query: 973 PNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRV 1152
++DD +EF T + I+GF E + R+ +AV+ +G ++F Q + +QA +
Sbjct: 320 ASIDDAEEFSLTDQAFDILGFTKQEKEDVYRITAAVMHMGGMKFKQRGREEQAEQDGEEE 379
Query: 1153 IQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLV 1332
+V L G EL K L+PRIKVG EFV + +N +Q ++ A+ K ++RLFKWLV
Sbjct: 380 GGRVSKLFGCDTAELYKNLLKPRIKVGNEFVTQGRNVQQVTNSIGALCKGVFDRLFKWLV 439
Query: 1333 TRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQE 1512
+ N++LD T ++ FIG+LDIAGFEIF+ N FEQ+CIN+TNEKLQQ FN+ MF+LEQE
Sbjct: 440 KKCNETLD-TQQKRQHFIGVLDIAGFEIFEYNGFEQLCINFTNEKLQQFFNHHMFVLEQE 498
Query: 1513 EYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NK 1689
EY+REGI+W FIDFG+DL IDLIEKPMG+L++L+EE +FPKA D++F EKL TH K
Sbjct: 499 EYKREGIDWAFIDFGMDLLACIDLIEKPMGILSILEEESMFPKATDQTFSEKLTNTHLGK 558
Query: 1690 HPKFIVPDM----RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVA 1857
F P + +HFA+ HYAG V Y+ WL KN DPLN+ VV + S + +
Sbjct: 559 SAPFQKPKPPKPGQQAAHFAIAHYAGCVSYNITGWLEKNKDPLNDTVVDQFKKSQNKLLI 618
Query: 1858 GIWKDAEFAGICAAEMNETAFGMRSRK-GMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCI 2034
I+ A+ AG E A G R +K G F TVS +KEQL LMTTLR+T PHFVRCI
Sbjct: 619 EIF--ADHAGQSGG--GEQAKGGRGKKGGGFATVSSAYKEQLNSLMTTLRSTQPHFVRCI 674
Query: 2035 IPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKN 2214
IPN K+ G ++++LV+ QL CNGVLEGIRICR+GFPNR+ + +F+ RY+IL P I K
Sbjct: 675 IPNEMKQPGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKMRYQILNPKGI-KG 733
Query: 2215 FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRG 2394
D K+ + +I + +++ + YR+G +KVFFR GVL +EE RD +L ++ QA RG
Sbjct: 734 IEDPKKCTKVLIESTELNDDQYRLGNTKVFFRAGVLGQMEEFRDERLGKIMSWMQAWARG 793
Query: 2395 FLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDD 2574
+LSR+ + N YL+LR W W++L+ KVKPLL V+R +DEI A+ +
Sbjct: 794 YLSRKGFKKLQEQRVALKVVQRNLRKYLQLRTWPWYKLWQKVKPLLNVSRIEDEI-ARLE 852
Query: 2575 ELRATKERLLKMEHDFRENEKKLD-QVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQ 2751
E E L E R+ + L+ +++ E+ + + L E + + +L +
Sbjct: 853 EKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQDYQERNAKLTAQKN 912
Query: 2752 ELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQ 2931
+LE + D+++RL+ ++K + + DK D
Sbjct: 913 DLENQLRDIQERLTQEEDARNQLFQQKKKADQEISGLKKDIEDLELNVQKAEQDKATKDH 972
Query: 2932 XXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHE 3111
+ + +L E++ H K K +LE L E
Sbjct: 973 QIRNLNDEIAHQDELINKLNKEKKMQGETNQKTGEELQAAEDKINHLNKVKAKLEQTLDE 1032
Query: 3112 LEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTR 3291
LE L RE++ + ++E+ KRK+ +L+ +++ +A+ +EL + ++D+EL +
Sbjct: 1033 LEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVADLERNKKELEQTIQRKDKELSSITAK 1092
Query: 3292 YDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDK 3471
++E V Q+Q++++Q I+EL E++E ER AR KAE R ++ +LE++ G+ L++
Sbjct: 1093 LEDEQVVVLKHQRQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEEL-GERLEE 1151
Query: 3472 VDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKK 3648
AT Q +L +++ E++ +R +E+ E + + K + V E+ +Q++Q K
Sbjct: 1152 AGGATSAQIELNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNK 1211
Query: 3649 QRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRT 3828
+++ EK++N+ + D+ + + +A +K K + L E+Q+ L DE RT
Sbjct: 1212 LKAKAEKEKNEYYGQLNDLRAGVDHITNEKAAQEKIAKQLQHTLNEVQSKL---DETNRT 1268
Query: 3829 LIDQLERSRDEL----DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIA 3996
L D + S+ +L L R EE E + + + + +R +
Sbjct: 1269 LND-FDASKKKLSIENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERAT 1327
Query: 3997 NINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHAARQGAGEARRKAEE---SVNQQLE 4164
+ + R LE + + L ++ +EEAEG +A L++++ A A R K E + +++LE
Sbjct: 1328 LLGKFRNLEHDLDNLREQVEEEAEG-KADLQRQLSKANAEAQVWRSKYESDGVARSEELE 1386
Query: 4165 ELRKKNLRDVEHLQKQLEESEVAKERILQ-------SKKKIQQELEDSSMELENVRASHR 4323
E ++K LQ +L E+E E + Q +K+++ E+ED +E++ A
Sbjct: 1387 EAKRK-------LQARLAEAEETIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIAN 1439
Query: 4324 DSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDR 4503
+EK+QK F+ + E ++ V + DA +E R+ T + L + +E LE R
Sbjct: 1440 AAEKKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRR 1499
Query: 4504 VRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLR 4683
++L E++D + + G+N+HE+EKA++ LEAE ++++ +EE E L+ E+ LR
Sbjct: 1500 ENKNLADEVKDLLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLR 1559
Query: 4684 LEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIEN 4863
++ ++ E DR I K+ E E R+ + + ++ LE E +GK+ A+ +KK+E
Sbjct: 1560 AQLELSQVRQEIDRRIQEKEEEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEA 1619
Query: 4864 QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRA 5043
I ELE L+ AN+ E + Q EE ++A++D L ++R+ A
Sbjct: 1620 DINELEIALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANA 1679
Query: 5044 VEAEREQ----LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXX 5211
++ E E+ L +A+ G QA ++ A+ IS+ KR+LE+++
Sbjct: 1680 LQNELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISA-AKRKLESELQTLHS 1738
Query: 5212 XXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITE 5391
+ + + +K +KA V ++ +L E+ Q E +++LE+ ++ + ++ E
Sbjct: 1739 DLDELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDE 1798
Query: 5392 LESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKR 5571
E+ A + + LE +V+ LE++L+ E + A + R+ E+R+ + + Q E++++
Sbjct: 1799 AEANALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRK 1858
Query: 5572 ANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQR---EADDLLDANEQ 5730
+E+ ++L++K K + +RQ++EAE+ + K R Q+ EA++ D EQ
Sbjct: 1859 NHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQ 1914
Score = 155 bits (391), Expect = 1e-35
Identities = 179/950 (18%), Positives = 386/950 (39%), Gaps = 62/950 (6%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDE 3267
RLE + + E+ E + + ELE KLLAE D L+ + G +++
Sbjct: 850 RLEEKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQD---------- 899
Query: 3268 ELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEK 3447
Y E +A +T Q D++ + +++E + E +ARN+ +++ ++
Sbjct: 900 --------YQERNAKLTA---QKNDLENQLRDIQERLTQEEDARNQLFQQKKKADQEISG 948
Query: 3448 VKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+K D+ D + + KD ++ I Q + K+ ++K ++ +
Sbjct: 949 LKKDIEDLELNVQKAEQDKATKDHQIRNLNDEIAH-QDELINKLNKEKKMQGETNQKTGE 1007
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAE 3807
+++ + + + L K + + +Q ++ + + R D++K ++ E L Q +A+
Sbjct: 1008 ELQAAEDKINHLNKVKAKLEQTLDELEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVAD 1067
Query: 3808 SDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL 3987
+ +K+ L ++R EL + E+E+ QR++
Sbjct: 1068 LERNKKELEQTIQRKDKELSSITAKLEDEQVVVLKHQRQIKELQA--------------- 1112
Query: 3988 KIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEE 4167
R +LE+E A + +AE RA L +E+ + GE +A + + Q+E
Sbjct: 1113 ------RIEELEEEVEAERQARAKAEKQRADLAREL----EELGERLEEAGGATSAQIE- 1161
Query: 4168 LRKKNLRDVEHLQKQLEESEVAKERILQS-KKKIQQELEDSSMELENVRASHRDSEKRQK 4344
L KK ++ L++ LEE+ + E L + +KK + + + +++ + +EK +
Sbjct: 1162 LNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNKLKAKAEKEKN 1221
Query: 4345 KFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQ 4524
++ Q+ + R V ++ A + + + + + +++D L + D ++ L
Sbjct: 1222 EYYGQLNDLRAGVDHITNEKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSI 1281
Query: 4525 ELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE--------------LE---DN 4653
E D + ++ V +L K K SL +L D + +E LE DN
Sbjct: 1282 ENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERATLLGKFRNLEHDLDN 1341
Query: 4654 L--QIAEDARLRLEVTNQALKSESDRAISNKDVEA---------EEKRRGLLKQIRDLEN 4800
L Q+ E+A + ++ Q K+ ++ + E+ EE +R L ++ + E
Sbjct: 1342 LREQVEEEAEGKADLQRQLSKANAEAQVWRSKYESDGVARSEELEEAKRKLQARLAEAEE 1401
Query: 4801 ELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEE 4980
+E+ + G ++++ ++ +L+ +++ AN + E++++ ++
Sbjct: 1402 TIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIANAAEKKQKAFDKIIGEWKLKVDD 1461
Query: 4981 ARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGG-G 5157
+ R + ++ E+ +E E + + K +GG
Sbjct: 1462 LAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGRN 1521
Query: 5158 ISSEEK--RRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKT 5331
I EK +RLEA+ + ++ E +K +AQ++L Q+ ++ +R + +K
Sbjct: 1522 IHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEI--DRRIQEKE 1579
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRARA--QMAALEAKVQYLEDQLNVEGQEKTAAN 5505
E + + + R + LE+ A+ +A A LEA + LE L+ + A
Sbjct: 1580 EEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQ 1639
Query: 5506 RAARRLEKRLNDTTQQFEDEKR----------------------------ANEQAKELLE 5601
+ +R +++L D E+E+R EQA
Sbjct: 1640 KNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRR 1699
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
++ + + QL+E + + R ++ E L ++L E N
Sbjct: 1700 QAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDELLNEAKN 1749
Score = 82.4 bits (202), Expect = 1e-13
Identities = 82/418 (19%), Positives = 183/418 (43%), Gaps = 25/418 (5%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L +Q+ E ++++ + + LE K +L A LE+++ L ++ KV +L + +E
Sbjct: 1511 LLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQE 1570
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ ++ +EE N ++ Q +D ++ +E E + +A ++++ A + ++
Sbjct: 1571 IDRRIQEKEEEFENTR------KNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINEL 1624
Query: 3451 KGDVLDKVDEATM-LQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+ LD ++A Q + R +++ + A+E+ Q + EQ R+ L +
Sbjct: 1625 E-IALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDA-REQLGISERRANALQN 1682
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL-- 3801
++E+ + Q ++ + QA+QE AD +++ + A A I ++ E+ L + ++L
Sbjct: 1683 ELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDE 1742
Query: 3802 ----AESDEHKRT--------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
A++ E K L D+L +D ++R+ E +Q RL A
Sbjct: 1743 LLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAEAN 1802
Query: 3946 XXXXXXXXXXXTRLKIANIN------RARQLEDEKNALLDEKEEAE-GLRAHLEKEIHAA 4104
++ + + R + +KN E+ E ++ +++ H
Sbjct: 1803 ALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRKNHER 1862
Query: 4105 RQGAGEARRKAEESVNQQLEELRK---KNLRDVEHLQKQLEESEVAKERILQSKKKIQ 4269
Q + ++ ++ +Q+EE + NL Q++LEE+E + Q+ K +
Sbjct: 1863 MQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQAISKFR 1920
>gi|24584696|ref|NP_724001.1| CG17927-PE [Drosophila melanogaster]
gi|22946661|gb|AAN10961.1| CG17927-PE [Drosophila melanogaster]
Length = 1962
Score = 1119 bits (2894), Expect = 0.0
Identities = 677/1916 (35%), Positives = 1078/1916 (55%), Gaps = 31/1916 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K CW+PD+ EG+L+G IK D V V L + I + V+K NPPKF+KIEDM++
Sbjct: 35 KKSCWIPDEKEGYLLGEIKATKGDIVSVGLQGGEVR-DIKSEKVEKVNPPKFEKIEDMAD 93
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
+T LN VLHNL+ RYY+ LIYTYSGLFCV INPYK+ P+Y+ + ++GK+R+E+PP
Sbjct: 94 MTVLNTPCVLHNLRQRYYAKLIYTYSGLFCVAINPYKRYPVYTNRCAKMYRGKRRNEVPP 153
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIFAI+D AY ML +QS+L TGESGAGKTENTKKVI Y A V +K + AA+
Sbjct: 154 HIFAISDGAYVDMLTNHVNQSMLITGESGAGKTENTKKVIAYFATVGA---SKKTDEAAK 210
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
G LE Q++Q NP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++G
Sbjct: 211 SK-----------GSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFGPTGKLAG 259
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLL-EGVDNYRFLVNRGITL 972
A+IE YLLEK+RV+ Q ERS+HIFYQI+ G K LL + + +Y + +T+
Sbjct: 260 ADIETYLLEKARVISQQSLERSYHIFYQIMSGSVPGVKDICLLTDNIYDYHIVSQGKVTV 319
Query: 973 PNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRV 1152
++DD +EF T + I+GF E + R+ +AV+ +G ++F Q + +QA +
Sbjct: 320 ASIDDAEEFSLTDQAFDILGFTKQEKEDVYRITAAVMHMGGMKFKQRGREEQAEQDGEEE 379
Query: 1153 IQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLV 1332
+V L G EL K L+PRIKVG EFV + +N +Q ++ A+ K ++RLFKWLV
Sbjct: 380 GGRVSKLFGCDTAELYKNLLKPRIKVGNEFVTQGRNVQQVTNSIGALCKGVFDRLFKWLV 439
Query: 1333 TRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQE 1512
+ N++LD T ++ FIG+LDIAGFEIF+ N FEQ+CIN+TNEKLQQ FN+ MF+LEQE
Sbjct: 440 KKCNETLD-TQQKRQHFIGVLDIAGFEIFEYNGFEQLCINFTNEKLQQFFNHHMFVLEQE 498
Query: 1513 EYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NK 1689
EYQREGIEW FIDFG+DLQ IDLIEKPMG+L++L+EE +FPKA D++F EKL TH K
Sbjct: 499 EYQREGIEWTFIDFGMDLQLCIDLIEKPMGILSILEEESMFPKATDQTFSEKLTNTHLGK 558
Query: 1690 HPKFIVPDM----RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVA 1857
F P + +HFA+ HYAG V Y+ WL KN DPLN+ VV + S + +
Sbjct: 559 SAPFQKPKPPKPGQQAAHFAIAHYAGCVSYNITGWLEKNKDPLNDTVVDQFKKSQNKLLI 618
Query: 1858 GIWKDAEFAGICAAEMNETAFGMRSRK-GMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCI 2034
I+ A+ AG E A G R +K G F TVS +KEQL LMTTLR+T PHFVRCI
Sbjct: 619 EIF--ADHAGQSGG--GEQAKGGRGKKGGGFATVSSAYKEQLNSLMTTLRSTQPHFVRCI 674
Query: 2035 IPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKN 2214
IPN K+ G ++++LV+ QL CNGVLEGIRICR+GFPNR+ + +F+ RY+I+ P ++ +
Sbjct: 675 IPNEMKQPGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKMRYKIMCPKLL-QG 733
Query: 2215 FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRG 2394
K++ +I +D+ + YR+G +KVFFR GVL +EE RD +L ++ QA RG
Sbjct: 734 VEKDKKATEIIIKFIDLPEDQYRLGNTKVFFRAGVLGQMEEFRDERLGKIMSWMQAWARG 793
Query: 2395 FLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDD 2574
+LSR+ + N YL+LR W W++L+ KVKPLL V+R +DEI A+ +
Sbjct: 794 YLSRKGFKKLQEQRVALKVVQRNLRKYLQLRTWPWYKLWQKVKPLLNVSRIEDEI-ARLE 852
Query: 2575 ELRATKERLLKMEHDFRENEKKLD-QVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQ 2751
E E L E R+ + L+ +++ E+ + + L E + + +L +
Sbjct: 853 EKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQDYQERNAKLTAQKN 912
Query: 2752 ELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQ 2931
+LE + D+++RL+ ++K + + DK D
Sbjct: 913 DLENQLRDIQERLTQEEDARNQLFQQKKKADQEISGLKKDIEDLELNVQKAEQDKATKDH 972
Query: 2932 XXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHE 3111
+ + +L E++ H K K +LE L E
Sbjct: 973 QIRNLNDEIAHQDELINKLNKEKKMQGETNQKTGEELQAAEDKINHLNKVKAKLEQTLDE 1032
Query: 3112 LEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTR 3291
LE L RE++ + ++E+ KRK+ +L+ +++ +A+ +EL + ++D+EL +
Sbjct: 1033 LEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVADLERNKKELEQTIQRKDKELSSITAK 1092
Query: 3292 YDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDK 3471
++E V Q+Q++++Q I+EL E++E ER AR KAE R ++ +LE++ G+ L++
Sbjct: 1093 LEDEQVVVLKHQRQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEEL-GERLEE 1151
Query: 3472 VDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKK 3648
AT Q +L +++ E++ +R +E+ E + + K + V E+ +Q++Q K
Sbjct: 1152 AGGATSAQIELNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNK 1211
Query: 3649 QRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRT 3828
+++ EK++N+ + D+ + + +A +K K + L E+Q+ L DE RT
Sbjct: 1212 LKAKAEKEKNEYYGQLNDLRAGVDHITNEKAAQEKIAKQLQHTLNEVQSKL---DETNRT 1268
Query: 3829 LIDQLERSRDEL----DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIA 3996
L D + S+ +L L R EE E + + + + +R +
Sbjct: 1269 LND-FDASKKKLSIENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERAT 1327
Query: 3997 NINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHAARQGAGEARRKAEE---SVNQQLE 4164
+ + R LE + + L ++ +EEAEG +A L++++ A A R K E + +++LE
Sbjct: 1328 LLGKFRNLEHDLDNLREQVEEEAEG-KADLQRQLSKANAEAQVWRSKYESDGVARSEELE 1386
Query: 4165 ELRKKNLRDVEHLQKQLEESEVAKERILQ-------SKKKIQQELEDSSMELENVRASHR 4323
E ++K LQ +L E+E E + Q +K+++ E+ED +E++ A
Sbjct: 1387 EAKRK-------LQARLAEAEETIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIAN 1439
Query: 4324 DSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDR 4503
+EK+QK F+ + E ++ V + DA +E R+ T + L + +E LE R
Sbjct: 1440 AAEKKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRR 1499
Query: 4504 VRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLR 4683
++L E++D + + G+N+HE+EKA++ LEAE ++++ +EE E L+ E+ LR
Sbjct: 1500 ENKNLADEVKDLLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLR 1559
Query: 4684 LEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIEN 4863
++ ++ E DR I K+ E E R+ + + ++ LE E +GK+ A+ +KK+E
Sbjct: 1560 AQLELSQVRQEIDRRIQEKEEEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEA 1619
Query: 4864 QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRA 5043
I ELE L+ AN+ E + Q EE ++A++D L ++R+ A
Sbjct: 1620 DINELEIALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANA 1679
Query: 5044 VEAEREQ----LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXX 5211
++ E E+ L +A+ G QA ++ A+ IS+ KR+LE+++
Sbjct: 1680 LQNELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISA-AKRKLESELQTLHS 1738
Query: 5212 XXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITE 5391
+ + + +K +KA V ++ +L E+ Q E +++LE+ ++ + ++ E
Sbjct: 1739 DLDELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDE 1798
Query: 5392 LESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKR 5571
E+ A + + LE +V+ LE++L+ E + A + R+ E+R+ + + Q E++++
Sbjct: 1799 AEANALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRK 1858
Query: 5572 ANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQR---EADDLLDANEQ 5730
+E+ ++L++K K + +RQ++EAE+ + K R Q+ EA++ D EQ
Sbjct: 1859 NHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQ 1914
Score = 155 bits (391), Expect = 1e-35
Identities = 179/950 (18%), Positives = 386/950 (39%), Gaps = 62/950 (6%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDE 3267
RLE + + E+ E + + ELE KLLAE D L+ + G +++
Sbjct: 850 RLEEKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQD---------- 899
Query: 3268 ELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEK 3447
Y E +A +T Q D++ + +++E + E +ARN+ +++ ++
Sbjct: 900 --------YQERNAKLTA---QKNDLENQLRDIQERLTQEEDARNQLFQQKKKADQEISG 948
Query: 3448 VKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+K D+ D + + KD ++ I Q + K+ ++K ++ +
Sbjct: 949 LKKDIEDLELNVQKAEQDKATKDHQIRNLNDEIAH-QDELINKLNKEKKMQGETNQKTGE 1007
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAE 3807
+++ + + + L K + + +Q ++ + + R D++K ++ E L Q +A+
Sbjct: 1008 ELQAAEDKINHLNKVKAKLEQTLDELEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVAD 1067
Query: 3808 SDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL 3987
+ +K+ L ++R EL + E+E+ QR++
Sbjct: 1068 LERNKKELEQTIQRKDKELSSITAKLEDEQVVVLKHQRQIKELQA--------------- 1112
Query: 3988 KIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEE 4167
R +LE+E A + +AE RA L +E+ + GE +A + + Q+E
Sbjct: 1113 ------RIEELEEEVEAERQARAKAEKQRADLAREL----EELGERLEEAGGATSAQIE- 1161
Query: 4168 LRKKNLRDVEHLQKQLEESEVAKERILQS-KKKIQQELEDSSMELENVRASHRDSEKRQK 4344
L KK ++ L++ LEE+ + E L + +KK + + + +++ + +EK +
Sbjct: 1162 LNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNKLKAKAEKEKN 1221
Query: 4345 KFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQ 4524
++ Q+ + R V ++ A + + + + + +++D L + D ++ L
Sbjct: 1222 EYYGQLNDLRAGVDHITNEKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSI 1281
Query: 4525 ELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE--------------LE---DN 4653
E D + ++ V +L K K SL +L D + +E LE DN
Sbjct: 1282 ENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERATLLGKFRNLEHDLDN 1341
Query: 4654 L--QIAEDARLRLEVTNQALKSESDRAISNKDVEA---------EEKRRGLLKQIRDLEN 4800
L Q+ E+A + ++ Q K+ ++ + E+ EE +R L ++ + E
Sbjct: 1342 LREQVEEEAEGKADLQRQLSKANAEAQVWRSKYESDGVARSEELEEAKRKLQARLAEAEE 1401
Query: 4801 ELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEE 4980
+E+ + G ++++ ++ +L+ +++ AN + E++++ ++
Sbjct: 1402 TIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIANAAEKKQKAFDKIIGEWKLKVDD 1461
Query: 4981 ARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGG-G 5157
+ R + ++ E+ +E E + + K +GG
Sbjct: 1462 LAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGRN 1521
Query: 5158 ISSEEK--RRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKT 5331
I EK +RLEA+ + ++ E +K +AQ++L Q+ ++ +R + +K
Sbjct: 1522 IHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEI--DRRIQEKE 1579
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRARA--QMAALEAKVQYLEDQLNVEGQEKTAAN 5505
E + + + R + LE+ A+ +A A LEA + LE L+ + A
Sbjct: 1580 EEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQ 1639
Query: 5506 RAARRLEKRLNDTTQQFEDEKR----------------------------ANEQAKELLE 5601
+ +R +++L D E+E+R EQA
Sbjct: 1640 KNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRR 1699
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
++ + + QL+E + + R ++ E L ++L E N
Sbjct: 1700 QAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDELLNEAKN 1749
Score = 82.4 bits (202), Expect = 1e-13
Identities = 82/418 (19%), Positives = 183/418 (43%), Gaps = 25/418 (5%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L +Q+ E ++++ + + LE K +L A LE+++ L ++ KV +L + +E
Sbjct: 1511 LLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQE 1570
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ ++ +EE N ++ Q +D ++ +E E + +A ++++ A + ++
Sbjct: 1571 IDRRIQEKEEEFENTR------KNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINEL 1624
Query: 3451 KGDVLDKVDEATM-LQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+ LD ++A Q + R +++ + A+E+ Q + EQ R+ L +
Sbjct: 1625 E-IALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDA-REQLGISERRANALQN 1682
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL-- 3801
++E+ + Q ++ + QA+QE AD +++ + A A I ++ E+ L + ++L
Sbjct: 1683 ELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDE 1742
Query: 3802 ----AESDEHKRT--------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
A++ E K L D+L +D ++R+ E +Q RL A
Sbjct: 1743 LLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAEAN 1802
Query: 3946 XXXXXXXXXXXTRLKIANIN------RARQLEDEKNALLDEKEEAE-GLRAHLEKEIHAA 4104
++ + + R + +KN E+ E ++ +++ H
Sbjct: 1803 ALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRKNHER 1862
Query: 4105 RQGAGEARRKAEESVNQQLEELRK---KNLRDVEHLQKQLEESEVAKERILQSKKKIQ 4269
Q + ++ ++ +Q+EE + NL Q++LEE+E + Q+ K +
Sbjct: 1863 MQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQAISKFR 1920
>gi|157892|gb|AAA28687.1| myosin heavy chain
Length = 1962
Score = 1118 bits (2892), Expect = 0.0
Identities = 675/1916 (35%), Positives = 1079/1916 (56%), Gaps = 31/1916 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K CW+PD+ EG+L+G IK D V V L + + +D +Q+ NPPK++K EDMS
Sbjct: 35 KKSCWIPDEKEGYLLGEIKATKGDIVSVGLQGGETR-DLKKDLLQQVNPPKYEKAEDMSN 93
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LTYLN+ASVLHNL+ RYY+ LIYTYSGLFCV INPYK+ P+Y+ + ++GK+R+E+PP
Sbjct: 94 LTYLNDASVLHNLRQRYYNKLIYTYSGLFCVAINPYKRYPVYTNRCAKMYRGKRRNEVPP 153
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIFAI+D AY ML +QS+L TGESGAGKTENTKKVI Y A V +K + AA+
Sbjct: 154 HIFAISDGAYVDMLTNHVNQSMLITGESGAGKTENTKKVIAYFATVGA---SKKTDEAAK 210
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
G LE Q++Q NP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++G
Sbjct: 211 SK-----------GSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFGPTGKLAG 259
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLL-EGVDNYRFLVNRGITL 972
A+IE YLLEK+RV+ Q ER +HIFYQI+ G K LL + + +Y + +T+
Sbjct: 260 ADIETYLLEKARVISQQSLERCYHIFYQIMSGSVPGVKDICLLTDNIYDYHIVSQGKVTV 319
Query: 973 PNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRV 1152
++DD +EF T + I+GF E + R+ +AV+ +G ++F Q + +QA +
Sbjct: 320 ASIDDAEEFSLTDQAFDILGFTKQEKEDVYRITAAVMHMGGMKFKQRGREEQAEQDGEEE 379
Query: 1153 IQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLV 1332
+V L G EL K L+PRIKVG EFV + +N +Q ++ A+ K ++RLFKWLV
Sbjct: 380 GGRVSKLFGCDTAELYKNLLKPRIKVGNEFVTQGRNVQQVTNSIGALCKGVFDRLFKWLV 439
Query: 1333 TRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQE 1512
+ N++LD T ++ FIG+LDIAGFEIF+ N FEQ+CIN+TNEKLQQ FN+ MF+LEQE
Sbjct: 440 KKCNETLD-TQQKRQHFIGVLDIAGFEIFEYNGFEQLCINFTNEKLQQFFNHHMFVLEQE 498
Query: 1513 EYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NK 1689
EY+REGI+W FIDFG+DL IDLIEKPMG+L++L+EE +FPKA D++F EKL TH K
Sbjct: 499 EYKREGIDWAFIDFGMDLLACIDLIEKPMGILSILEEESMFPKATDQTFSEKLTNTHLGK 558
Query: 1690 HPKFIVPDM----RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVA 1857
F P + +HFA+ HYAG V Y+ WL KN DPLN+ VV + S + +
Sbjct: 559 SAPFQKPKPPKPGQQAAHFAIAHYAGCVSYNITGWLEKNKDPLNDTVVDQFKKSQNKLLI 618
Query: 1858 GIWKDAEFAGICAAEMNETAFGMRSRK-GMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCI 2034
I+ A+ AG E A G R +K G F TVS +KEQL LMTTLR+T PHFVRCI
Sbjct: 619 EIF--ADHAGQSGG--GEQAKGGRGKKGGGFATVSSAYKEQLNSLMTTLRSTQPHFVRCI 674
Query: 2035 IPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKN 2214
IPN K+ G ++++LV+ QL CNGVLEGIRICR+GFPNR+ + +F+ RY+I+ P ++ +
Sbjct: 675 IPNEMKQPGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKMRYKIMCPKLL-QG 733
Query: 2215 FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRG 2394
K++ +I +D+ + YR+G +KVFFR GVL +EE RD +L ++ QA RG
Sbjct: 734 VEKDKKATEIIIKFIDLPEDQYRLGNTKVFFRAGVLGQMEEFRDERLGKIMSWMQAWARG 793
Query: 2395 FLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDD 2574
+LSR+ + N YL+LR W W++L+ KVKPLL V+R +DEI A+ +
Sbjct: 794 YLSRKGFKKLQEQRVALKVVQRNLRKYLQLRTWPWYKLWQKVKPLLNVSRIEDEI-ARLE 852
Query: 2575 ELRATKERLLKMEHDFRENEKKLD-QVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQ 2751
E E L E R+ + L+ +++ E+ + + L E + + +L +
Sbjct: 853 EKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQDYQERNAKLTAQKN 912
Query: 2752 ELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQ 2931
+LE + D+++RL+ ++K + + DK D
Sbjct: 913 DLENQLRDIQERLTQEEDARNQLFQQKKKADQEISGLKKDIEDLELNVQKAEQDKATKDH 972
Query: 2932 XXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHE 3111
+ + +L E++ H K K +LE L E
Sbjct: 973 QIRNLNDEIAHQDELINKLNKEKKMQGETNQKTGEELQAAEDKINHLNKVKAKLEQTLDE 1032
Query: 3112 LEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTR 3291
LE L RE++ + ++E+ KRK+ +L+ +++ +A+ +EL + ++D+EL +
Sbjct: 1033 LEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVADLERNKKELEQTIQRKDKELSSITAK 1092
Query: 3292 YDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDK 3471
++E V Q+Q++++Q I+EL E++E ER AR KAE R ++ +LE++ G+ L++
Sbjct: 1093 LEDEQVVVLKHQRQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEEL-GERLEE 1151
Query: 3472 VDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKK 3648
AT Q +L +++ E++ +R +E+ E + + K + V E+ +Q++Q K
Sbjct: 1152 AGGATSAQIELNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNK 1211
Query: 3649 QRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRT 3828
+++ EK++N+ + D+ + + +A +K K + L E+Q+ L DE RT
Sbjct: 1212 LKAKAEKEKNEYYGQLNDLRAGVDHITNEKAAQEKIAKQLQHTLNEVQSKL---DETNRT 1268
Query: 3829 LIDQLERSRDEL----DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIA 3996
L D + S+ +L L R EE E + + + + +R +
Sbjct: 1269 LND-FDASKKKLSIENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERAT 1327
Query: 3997 NINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHAARQGAGEARRKAEE---SVNQQLE 4164
+ + R LE + + L ++ +EEAEG +A L++++ A A R K E + +++LE
Sbjct: 1328 LLGKFRNLEHDLDNLREQVEEEAEG-KADLQRQLSKANAEAQVWRSKYESDGVARSEELE 1386
Query: 4165 ELRKKNLRDVEHLQKQLEESEVAKERILQ-------SKKKIQQELEDSSMELENVRASHR 4323
E ++K LQ +L E+E E + Q +K+++ E+ED +E++ A
Sbjct: 1387 EAKRK-------LQARLAEAEETIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIAN 1439
Query: 4324 DSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDR 4503
+EK+QK F+ + E ++ V + DA +E R+ T + L + +E LE R
Sbjct: 1440 AAEKKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRR 1499
Query: 4504 VRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLR 4683
++L E++D + + G+N+HE+EKA++ LEAE ++++ +EE E L+ E+ LR
Sbjct: 1500 ENKNLADEVKDLLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLR 1559
Query: 4684 LEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIEN 4863
++ ++ E DR I K+ E E R+ + + ++ LE E +GK+ A+ +KK+E
Sbjct: 1560 AQLELSQVRQEIDRRIQEKEEEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEA 1619
Query: 4864 QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRA 5043
I ELE L+ AN+ E + Q EE ++A++D L ++R+ A
Sbjct: 1620 DINELEIALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANA 1679
Query: 5044 VEAEREQ----LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXX 5211
++ E E+ L +A+ G QA ++ A+ IS+ KR+LE+++
Sbjct: 1680 LQNELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISA-AKRKLESELQTLHS 1738
Query: 5212 XXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITE 5391
+ + + +K +KA V ++ +L E+ Q E +++LE+ ++ + ++ E
Sbjct: 1739 DLDELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDE 1798
Query: 5392 LESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKR 5571
E+ A + + LE +V+ LE++L+ E + A + R+ E+R+ + + Q E++++
Sbjct: 1799 AEANALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRK 1858
Query: 5572 ANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQR---EADDLLDANEQ 5730
+E+ ++L++K K + +RQ++EAE+ + K R Q+ EA++ D EQ
Sbjct: 1859 NHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQ 1914
Score = 155 bits (391), Expect = 1e-35
Identities = 179/950 (18%), Positives = 386/950 (39%), Gaps = 62/950 (6%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDE 3267
RLE + + E+ E + + ELE KLLAE D L+ + G +++
Sbjct: 850 RLEEKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQD---------- 899
Query: 3268 ELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEK 3447
Y E +A +T Q D++ + +++E + E +ARN+ +++ ++
Sbjct: 900 --------YQERNAKLTA---QKNDLENQLRDIQERLTQEEDARNQLFQQKKKADQEISG 948
Query: 3448 VKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+K D+ D + + KD ++ I Q + K+ ++K ++ +
Sbjct: 949 LKKDIEDLELNVQKAEQDKATKDHQIRNLNDEIAH-QDELINKLNKEKKMQGETNQKTGE 1007
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAE 3807
+++ + + + L K + + +Q ++ + + R D++K ++ E L Q +A+
Sbjct: 1008 ELQAAEDKINHLNKVKAKLEQTLDELEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVAD 1067
Query: 3808 SDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL 3987
+ +K+ L ++R EL + E+E+ QR++
Sbjct: 1068 LERNKKELEQTIQRKDKELSSITAKLEDEQVVVLKHQRQIKELQA--------------- 1112
Query: 3988 KIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEE 4167
R +LE+E A + +AE RA L +E+ + GE +A + + Q+E
Sbjct: 1113 ------RIEELEEEVEAERQARAKAEKQRADLAREL----EELGERLEEAGGATSAQIE- 1161
Query: 4168 LRKKNLRDVEHLQKQLEESEVAKERILQS-KKKIQQELEDSSMELENVRASHRDSEKRQK 4344
L KK ++ L++ LEE+ + E L + +KK + + + +++ + +EK +
Sbjct: 1162 LNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNKLKAKAEKEKN 1221
Query: 4345 KFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQ 4524
++ Q+ + R V ++ A + + + + + +++D L + D ++ L
Sbjct: 1222 EYYGQLNDLRAGVDHITNEKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSI 1281
Query: 4525 ELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE--------------LE---DN 4653
E D + ++ V +L K K SL +L D + +E LE DN
Sbjct: 1282 ENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERATLLGKFRNLEHDLDN 1341
Query: 4654 L--QIAEDARLRLEVTNQALKSESDRAISNKDVEA---------EEKRRGLLKQIRDLEN 4800
L Q+ E+A + ++ Q K+ ++ + E+ EE +R L ++ + E
Sbjct: 1342 LREQVEEEAEGKADLQRQLSKANAEAQVWRSKYESDGVARSEELEEAKRKLQARLAEAEE 1401
Query: 4801 ELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEE 4980
+E+ + G ++++ ++ +L+ +++ AN + E++++ ++
Sbjct: 1402 TIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIANAAEKKQKAFDKIIGEWKLKVDD 1461
Query: 4981 ARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGG-G 5157
+ R + ++ E+ +E E + + K +GG
Sbjct: 1462 LAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGRN 1521
Query: 5158 ISSEEK--RRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKT 5331
I EK +RLEA+ + ++ E +K +AQ++L Q+ ++ +R + +K
Sbjct: 1522 IHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEI--DRRIQEKE 1579
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRARA--QMAALEAKVQYLEDQLNVEGQEKTAAN 5505
E + + + R + LE+ A+ +A A LEA + LE L+ + A
Sbjct: 1580 EEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQ 1639
Query: 5506 RAARRLEKRLNDTTQQFEDEKR----------------------------ANEQAKELLE 5601
+ +R +++L D E+E+R EQA
Sbjct: 1640 KNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRR 1699
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
++ + + QL+E + + R ++ E L ++L E N
Sbjct: 1700 QAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDELLNEAKN 1749
Score = 82.4 bits (202), Expect = 1e-13
Identities = 82/418 (19%), Positives = 183/418 (43%), Gaps = 25/418 (5%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L +Q+ E ++++ + + LE K +L A LE+++ L ++ KV +L + +E
Sbjct: 1511 LLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQE 1570
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ ++ +EE N ++ Q +D ++ +E E + +A ++++ A + ++
Sbjct: 1571 IDRRIQEKEEEFENTR------KNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINEL 1624
Query: 3451 KGDVLDKVDEATM-LQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+ LD ++A Q + R +++ + A+E+ Q + EQ R+ L +
Sbjct: 1625 E-IALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDA-REQLGISERRANALQN 1682
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL-- 3801
++E+ + Q ++ + QA+QE AD +++ + A A I ++ E+ L + ++L
Sbjct: 1683 ELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDE 1742
Query: 3802 ----AESDEHKRT--------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
A++ E K L D+L +D ++R+ E +Q RL A
Sbjct: 1743 LLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAEAN 1802
Query: 3946 XXXXXXXXXXXTRLKIANIN------RARQLEDEKNALLDEKEEAE-GLRAHLEKEIHAA 4104
++ + + R + +KN E+ E ++ +++ H
Sbjct: 1803 ALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRKNHER 1862
Query: 4105 RQGAGEARRKAEESVNQQLEELRK---KNLRDVEHLQKQLEESEVAKERILQSKKKIQ 4269
Q + ++ ++ +Q+EE + NL Q++LEE+E + Q+ K +
Sbjct: 1863 MQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQAISKFR 1920
>gi|50757617|ref|XP_415579.1| PREDICTED: similar to skeletal myosin
heavy chain [Gallus gallus]
Length = 1939
Score = 1118 bits (2892), Expect = 0.0
Identities = 650/1891 (34%), Positives = 1061/1891 (55%), Gaps = 17/1891 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V E ++ +I+ + + +V V+ ++ +T+ D + NPPK+DKIEDM+ +T+L
Sbjct: 39 FVVHAKESYVKSTIQSKESGKVTVK-TESGETLTVKEDQIFSMNPPKYDKIEDMAMMTHL 97
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 98 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVLAYRGKKRQEAPPHIFS 157
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A + K
Sbjct: 158 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAASGDKKK---------- 207
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
++ G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 208 EEQPAGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIE 267
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPNV 981
YLLEKSRV Q + ERS+HIFYQI+ E E LL + +Y ++ IT+P++
Sbjct: 268 TYLLEKSRVTFQLKAERSYHIFYQIMSN-KKPELIEMLLITTNPYDYHYVSQGEITVPSI 326
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
+D +E +T +++ I+GF DE ++I ++ AV+ GNL+F Q+++ +QA V K
Sbjct: 327 NDQEELMATDSAIDILGFTPDEKTAIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADK 386
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L+GL +L KA PR+KVG EFV K Q +Q +V A+AKA +E++F W+V RI
Sbjct: 387 AAYLMGLNSADLLKALCYPRVKVGNEFVTKGQTVQQVYNSVGALAKAVFEKMFLWMVVRI 446
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 447 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H K
Sbjct: 506 KEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNN 565
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P ++++HF++VHYAG VDY+ WL KN DPLNE VVGL Q S+ +A ++
Sbjct: 566 FQKPKPGKGKAEAHFSLVHYAGTVDYNISGWLDKNKDPLNETVVGLYQKSSLKTLALLFA 625
Query: 1870 DAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHE 2049
AG A G + + F+TVS L +E L KLMT LR+T PHFVRCIIPN
Sbjct: 626 S---AGGEAESGGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 682
Query: 2050 KKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDG 2226
K G + LVL QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L IP+ FID
Sbjct: 683 KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDS 742
Query: 2227 KESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSR 2406
K++ K++ ++D+D Y+ G +KVFF+ G+L LEE RD KL LI QA+CRGFL R
Sbjct: 743 KKASEKLLGSIDVDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQARCRGFLMR 802
Query: 2407 RLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRA 2586
Y N +++ +++W W +LF K+KPLL+ ++ E+ E
Sbjct: 803 VEYRRMVERRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAESEKEMANMKGEFEK 862
Query: 2587 TKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYI 2766
TKE L K E +E E+K+ ++ E+ +Q Q+Q E++ A+ ++ +L +LE
Sbjct: 863 TKEELAKSEAKRKELEEKMVSLLQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEAK 922
Query: 2767 VNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXX 2946
+ ++ +R +RK + + +K +
Sbjct: 923 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 982
Query: 2947 XXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDL 3126
+ L E++ KAK +LE Q+ +LE L
Sbjct: 983 TEEMAALDENIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSL 1042
Query: 3127 NRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEES 3306
+E++ + +LE+ KRKL +L+ + D + + ++L+ +L K+D E+ ++ ++E
Sbjct: 1043 EQEKKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQ 1102
Query: 3307 ANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT 3486
A +QK+++++Q +EL E++E ER +R KAE R ++ +LE++ + L++ AT
Sbjct: 1103 ALGMQLQKKIKELQARTEELEEEIEAERTSRAKAEKHRADLSRELEEI-SERLEEAGGAT 1161
Query: 3487 MLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQL 3663
Q D+ +++ E +R +E+ E + K + EL +QI+ ++ + +L
Sbjct: 1162 AAQIDMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKL 1221
Query: 3664 EKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLID-- 3837
EK++++ E D+A + + ++A ++K + E L EI+ + +EH+R + D
Sbjct: 1222 EKEKSELKMEIDDLASNMESVSKAKASLEKTCRALEDQLSEIK---TKEEEHQRMINDVN 1278
Query: 3838 -QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRAR 4014
Q R + E +R EE++ + + R + K A + +
Sbjct: 1279 AQRARLQTESGEYSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKNALAHGLQ 1338
Query: 4015 QLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDV 4194
+ + L ++ EE + + L++ + A + R K E Q+ EEL + +
Sbjct: 1339 SARHDCDLLREQYEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA 1398
Query: 4195 EHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMA 4365
+ LQ E E + + ++K+++Q E+ED +++E ++ +K+QK F+ ++
Sbjct: 1399 QRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERANSACAALDKKQKNFDKILS 1458
Query: 4366 EERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSIS 4545
E + ++ + +A +E R T + + N + +HLE R ++LQQE+ D
Sbjct: 1459 EWKQKYEETQAELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEISDLTE 1518
Query: 4546 NKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDR 4725
+ GK +HELEK K+ +E E ++++ +EE E +L+ E LRL++ +KSE DR
Sbjct: 1519 QIAEGGKAIHELEKVKKQIEQEKSELQASLEEAEASLEHEEGKILRLQLELNQVKSEIDR 1578
Query: 4726 AISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANR 4905
I+ KD E ++ +R L+ + +++ L+ E R ++ A+ +KK+E + E+E QL ANR
Sbjct: 1579 KIAEKDEEIDQLKRNHLRIVESMQSTLDAEVRSRNEALRLKKKMEGDLNEMEIQLNHANR 1638
Query: 4906 LKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEG 5085
+ E + QI ++A +++ED+ + +R+ ++AE E+LR A E
Sbjct: 1639 MAAEAQRNLRNTQGVLKDTQIHLDDALRSQEDLKEQVAMVERRANLLQAETEELRAALEQ 1698
Query: 5086 LMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDK 5256
++RK Q K++LE+ I+Q A +K
Sbjct: 1699 TERSRKVAEQELLDASERVQLLHTQNTSLINTKKKLESDISQIQSEMEDTIQEARNAEEK 1758
Query: 5257 QRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAA 5436
+KA + +L E+ + E K++L+++ +D + ++ E E A + Q+
Sbjct: 1759 AKKAITDAAMMAEELKKEQDTSAHLERMKKNLDQTVKDLQHRLDEAEQLALKGGKKQIQK 1818
Query: 5437 LEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLK 5616
LEA+V+ LE +++ E + A + R+ E+R+ + T Q E++++ + ++L++K +K
Sbjct: 1819 LEARVRELEGEVDAEQKRSAEAVKGVRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQMK 1878
Query: 5617 NRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
++ +RQ +EAE+ + +K R +Q E ++
Sbjct: 1879 VKSYKRQAEEAEELSNVNLSKFRKIQHELEE 1909
Score = 160 bits (406), Expect = 3e-37
Identities = 194/952 (20%), Positives = 396/952 (41%), Gaps = 54/952 (5%)
Frame = +1
Query: 3040 LLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL--- 3210
LL E K KG E + +++L + + ELE+ LL E D + +
Sbjct: 843 LLKSAESEKEMANMKGEFE----KTKEELAKSEAKRKELEEKMVSLLQEKNDLQLQVQAE 898
Query: 3211 AEKMGKVEELNNQLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELRED 3375
A+ + EE +QL+K +L+ ++ DEE N L K+ R ++ EL++D
Sbjct: 899 ADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKD 957
Query: 3376 METERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQI 3555
++ E+T +V + + V + +E L + +++ +E A + A +Q
Sbjct: 958 IDD-------LELTLAKVEKEKHATENKVKNLTEEMAALDENIAKLTKEKKALQEAHQQT 1010
Query: 3556 QHTMEGK------IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEI 3717
++ + + + K K +QV++L +EQ KK R LE+ + + + + I
Sbjct: 1011 LDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAHDSI 1070
Query: 3718 ALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEE 3897
L+ + +D+K K + + +IQ+ + E ++ L QL++ EL R E EE
Sbjct: 1071 MDLENDKQQLDEKLKKKDFEISQIQSKI----EDEQALGMQLQKKIKELQ--ARTEELEE 1124
Query: 3898 HAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRA 4077
A R RL+ A A Q++ +++K EAE
Sbjct: 1125 EIEAERTSRAKAEKHRADLSRELEEISERLEEAGGATAAQID------MNKKREAE---- 1174
Query: 4078 HLEKEIHAARQGAGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERIL 4248
+ RR EE+ Q LRKK+ L +Q++ + K+++
Sbjct: 1175 ------------FQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLE 1222
Query: 4249 QSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEER------------VAVQKA 4392
+ K +++ E++D + +E+V + EK + E Q++E + V Q+A
Sbjct: 1223 KEKSELKMEIDDLASNMESVSKAKASLEKTCRALEDQLSEIKTKEEEHQRMINDVNAQRA 1282
Query: 4393 LLDRDA--MSQELRDRETRVLSL-------LNEVDIMKEHLEESDRVRRSLQQELQDSIS 4545
L ++ S+++ +++ + L +++ +K HLEE + + +L LQ +
Sbjct: 1283 RLQTESGEYSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKNALAHGLQSARH 1342
Query: 4546 NKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDR 4725
+ D + E ++AK L+ L ++ EV K E+D
Sbjct: 1343 DCDLLREQYEEEQEAKGELQRAL-------------------SKANSEVAQWRTKYETD- 1382
Query: 4726 AISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVAN- 4902
AI + E EE ++ L ++++D E +E + +++++N++ +L +E AN
Sbjct: 1383 AIQRTE-ELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERANS 1441
Query: 4903 ------RLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQ 5064
+ ++ + E Q E E +++ ++ L + + E
Sbjct: 1442 ACAALDKKQKNFDKILSEWKQKYEETQAELEASQKESRSLSTELFKMKNAYEESLDHLET 1501
Query: 5065 LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSE---EKRRLEAKIAQXXXXXXXXQSN 5235
L+ N+ L Q A+GG E K+++E + ++ +++
Sbjct: 1502 LKRENKNLQQEISDLTEQI-------AEGGKAIHELEKVKKQIEQEKSELQASLEEAEAS 1554
Query: 5236 CELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSR 5415
E K + Q++L Q+ ++ +++K + + +++ R++ + ++S +
Sbjct: 1555 LEHEEGKILRLQLELNQVKSE------IDRKIAEKDEEIDQLKRNHLRIVESMQSTLDAE 1608
Query: 5416 ARAQMAAL------EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRAN 5577
R++ AL E + +E QLN + A R R + L DT +D R+
Sbjct: 1609 VRSRNEALRLKKKMEGDLNEMEIQLNHANRMAAEAQRNLRNTQGVLKDTQIHLDDALRSQ 1668
Query: 5578 EQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQL 5733
E KE + + L+ + +E + + + ++E LLDA+E++
Sbjct: 1669 EDLKEQVAMVERRANLLQAETEELRAALEQTERSRKVAEQE---LLDASERV 1717
Score = 141 bits (356), Expect = 2e-31
Identities = 183/930 (19%), Positives = 384/930 (40%), Gaps = 72/930 (7%)
Frame = +1
Query: 3166 KRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDM 3345
K K L + +S+ +A G+ E+ +L K + + R + E V+L+Q++
Sbjct: 839 KIKPLLKSAESEKEMANMKGEFEKTKEELAKSEAK------RKELEEKMVSLLQEK---- 888
Query: 3346 QTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEV 3525
++L+ ++ E +A AE E QL K K + K+ E T + +EE+
Sbjct: 889 ----NDLQLQVQAEADALADAE----ERCDQLIKTKIQLEAKIKEVTE----RAEDEEEI 936
Query: 3526 NATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADM 3705
NA ++ +K K + EL I+ + +++EK+++ + + ++
Sbjct: 937 NA--------------ELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 982
Query: 3706 AQEIALLQASRADIDKKRK-IHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRV 3882
+E+A L + A + K++K + EAH + AE D+ TL + ++D L
Sbjct: 983 TEEMAALDENIAKLTKEKKALQEAHQQTLDDLQAEEDK-VNTLTKAKTKLEQQVDDLEGS 1041
Query: 3883 REEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEA 4062
E+E+ +++R LK+A+ + LE++K L ++ ++
Sbjct: 1042 LEQEKKLRMDLERAKRKLEGD-------------LKLAH-DSIMDLENDKQQLDEKLKKK 1087
Query: 4063 EGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKER 4242
+ + ++ +I + E+++ QL++ K+ E L++++E ++ +
Sbjct: 1088 DFEISQIQSKI------------EDEQALGMQLQKKIKELQARTEELEEEIEAERTSRAK 1135
Query: 4243 ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQE 4422
+ + + +ELE+ S LE + KK E++ + R +++A L +A +
Sbjct: 1136 AEKHRADLSRELEEISERLEEAGGATAAQIDMNKKREAEFQKMRRDLEEATLQHEATAAA 1195
Query: 4423 LRDRETRVLSLLNE-VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRS 4599
LR + + L E +D ++ ++ ++ + L+ E+ D SN + K LEK R+
Sbjct: 1196 LRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMESVSKAKASLEKTCRA 1255
Query: 4600 LEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRG--- 4770
LE +L++++ + EE + + R RL+ + E R + KD + RG
Sbjct: 1256 LEDQLSEIKTKEEEHQRMINDVNAQRARLQTES----GEYSRQVEEKDALISQLSRGKQA 1311
Query: 4771 LLKQIRDLENELENEKRGKS----GAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXX 4938
+QI +L+ LE E + K+ G S R + + E++ E L+
Sbjct: 1312 FTQQIEELKRHLEEEIKAKNALAHGLQSARHDCDLLREQYEEEQEAKGELQRALSKANSE 1371
Query: 4939 XXXXXXEYQIEC----EEARQAKEDIAALLREADRKFRAV-------EAEREQLREANEG 5085
+Y+ + EE +AK+ +A L++A+ AV E +++L+ E
Sbjct: 1372 VAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVED 1431
Query: 5086 LMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQS----------- 5232
LM ++ + I SE K++ E A+ +S
Sbjct: 1432 LMIDVERANSACAALDKKQKNFDKILSEWKQKYEETQAELEASQKESRSLSTELFKMKNA 1491
Query: 5233 ------NCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITEL 5394
+ E + + Q ++ +T ++ + E K+ +E+ + +A + E
Sbjct: 1492 YEESLDHLETLKRENKNLQQEISDLTEQIAEGGKAIHELEKVKKQIEQEKSELQASLEEA 1551
Query: 5395 ESGAQSRA----RAQMAALEAK------------------------VQYLEDQLNVEGQE 5490
E+ + R Q+ + K V+ ++ L+ E +
Sbjct: 1552 EASLEHEEGKILRLQLELNQVKSEIDRKIAEKDEEIDQLKRNHLRIVESMQSTLDAEVRS 1611
Query: 5491 KTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEA------- 5649
+ A R +++E LN+ Q R +A+ L + ++ + LD+A
Sbjct: 1612 RNEALRLKKKMEGDLNEMEIQLNHANRMAAEAQRNLRNTQGVLKDTQIHLDDALRSQEDL 1671
Query: 5650 EDEMSRERTKHRNVQREADDLLDANEQLTR 5739
+++++ + +Q E ++L A EQ R
Sbjct: 1672 KEQVAMVERRANLLQAETEELRAALEQTER 1701
Score = 100 bits (250), Expect = 3e-19
Identities = 98/485 (20%), Positives = 208/485 (42%), Gaps = 17/485 (3%)
Frame = +1
Query: 2968 QDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYK 3147
++AY+ L ++ D E+ G KA +HELE+ K
Sbjct: 1489 KNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKA-------IHELEK-------VK 1534
Query: 3148 SELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQ 3327
++EQ K +L A LE+++ L + GK+ L +L + E+ ++ DEE +
Sbjct: 1535 KQIEQEKSELQASLEEAEASLEHEEGKILRLQLELNQVKSEIDRKIAEKDEE------ID 1588
Query: 3328 KQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMS 3507
+ R+ ++ ++ ++ E +RN+A ++++ L +++ + A Q +
Sbjct: 1589 QLKRNHLRIVESMQSTLDAEVRSRNEALRLKKKMEGDLNEMEIQLNHANRMAAEAQRNLR 1648
Query: 3508 RKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQAD 3687
+ T+ ++ + E ++EQ A R+ L + E+ + Q E+ + A+
Sbjct: 1649 NTQGVLKDTQIHLDDALRSQED-LKEQVAMVERRANLLQAETEELRAALEQTERSRKVAE 1707
Query: 3688 QERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRT------------- 3828
QE D ++ + LL + +K E+ + +IQ+ + ++ + R
Sbjct: 1708 QELLDASERVQLLHTQNTSLINTKKKLESDISQIQSEMEDTIQEARNAEEKAKKAITDAA 1767
Query: 3829 -LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANIN 4005
+ ++L++ +D HL R+++ + ++Q RL A + +I +
Sbjct: 1768 MMAEELKKEQDTSAHLERMKKNLDQTVKDLQHRLDEAEQLALKGG-------KKQIQKLE 1820
Query: 4006 -RARQLEDEKNALLDEKEEAEGLRA--HLEKEIHAARQGAGEARRKAEESVNQQLEELRK 4176
R R+LE E +A ++K AE ++ E+ + + E R+ +L++L
Sbjct: 1821 ARVRELEGEVDA--EQKRSAEAVKGVRKYERRVKELTYQSEEDRKNV-----LRLQDLVD 1873
Query: 4177 KNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFES 4356
K V+ ++Q EE+E L +KIQ ELE++ + + + ++F
Sbjct: 1874 KLQMKVKSYKRQAEEAEELSNVNLSKFRKIQHELEEAEERADIAESQVNKLRVKSREFHK 1933
Query: 4357 QMAEE 4371
++ EE
Sbjct: 1934 KIEEE 1938
Score = 67.8 bits (164), Expect = 3e-09
Identities = 97/457 (21%), Positives = 195/457 (42%), Gaps = 40/457 (8%)
Frame = +1
Query: 4492 ESDRVRRSLQQELQDSISNKDDFGKNV---HELEKAKRSLEAELNDMRVQMEELEDNLQI 4662
ES++ +++ E + + K++ K+ ELE+ SL E ND+++Q++ D L
Sbjct: 848 ESEKEMANMKGEFEKT---KEELAKSEAKRKELEEKMVSLLQEKNDLQLQVQAEADALAD 904
Query: 4663 AE---DARLRLEVTNQA-LKSESDRAISNKDVEAE--EKRRGLLKQIRDLENELENEKRG 4824
AE D ++ ++ +A +K ++RA +++ AE K+R L + +L+ ++++ +
Sbjct: 905 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 964
Query: 4825 KSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDI 5004
+ + EN++ L +++ +E E + + QA+ED
Sbjct: 965 LAKVEKEKHATENKVKNLTEEMAAL----DENIAKLTKEKKALQEAHQQTLDDLQAEEDK 1020
Query: 5005 AALLREADRKFRA----VEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEE 5172
L +A K +E EQ ++ L +A+++ +
Sbjct: 1021 VNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAHDSIMD----LEND 1076
Query: 5173 KRRLEAKIAQXXXXXXXXQSNCE----LAIDKQRKA---QVQLEQITTDLSMERTLNQKT 5331
K++L+ K+ + QS E L + Q+K Q + E++ ++ ERT K
Sbjct: 1077 KQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQARTEELEEEIEAERTSRAKA 1136
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRARAQM-AALEAKVQYLEDQLNVEGQEKTAANR 5508
E + L R + ++ E +G + A+ M EA+ Q + L +E T +
Sbjct: 1137 EKHRADLSRELEEISERLEE--AGGATAAQIDMNKKREAEFQKMRRDL----EEATLQHE 1190
Query: 5509 A-ARRLEKRLNDTTQQFEDEKRANEQAKELLEK-------------SNLKN-----RNLR 5631
A A L K+ D+T + ++ ++ K+ LEK SN+++ +L
Sbjct: 1191 ATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMESVSKAKASLE 1250
Query: 5632 RQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
+ ED++S +TK QR +D+ +L E
Sbjct: 1251 KTCRALEDQLSEIKTKEEEHQRMINDVNAQRARLQTE 1287
Score = 50.4 bits (119), Expect = 5e-04
Identities = 76/349 (21%), Positives = 132/349 (37%), Gaps = 51/349 (14%)
Frame = +1
Query: 4852 KIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADR 5031
KI+ + E + E+AN +K E+ + ++ +E + +LL+E +
Sbjct: 839 KIKPLLKSAESEKEMAN-MKGEFEKTKEELAKSEAK-------RKELEEKMVSLLQEKND 890
Query: 5032 KFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXX 5211
V+AE + L +A E Q K K +LEAKI +
Sbjct: 891 LQLQVQAEADALADAEERCDQLIKT----------------------KIQLEAKIKEVTE 928
Query: 5212 XXXXXQS-NCELAIDKQRKAQVQLEQITTDLS-MERTLNQKTEAEKQSLERSNRDYKAKI 5385
+ N EL K+RK + + ++ D+ +E TL K E EK + E ++ ++
Sbjct: 929 RAEDEEEINAELTA-KKRKLEDECSELKKDIDDLELTL-AKVEKEKHATENKVKNLTEEM 986
Query: 5386 TELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDE 5565
L+ + + A EA Q L+D L E + +A +LE++++D E E
Sbjct: 987 AALDENIAKLTKEKKALQEAHQQTLDD-LQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQE 1045
Query: 5566 KRAN---EQAKELLE----------------KSNL------------------------- 5613
K+ E+AK LE K L
Sbjct: 1046 KKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALG 1105
Query: 5614 -----KNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
K + L+ + +E E+E+ ERT ++ DL E+++ L
Sbjct: 1106 MQLQKKIKELQARTEELEEEIEAERTSRAKAEKHRADLSRELEEISERL 1154
>gi|21907900|dbj|BAC05680.1| myosin heavy chain 2x [Equus caballus]
Length = 1938
Score = 1117 bits (2888), Expect = 0.0
Identities = 652/1889 (34%), Positives = 1051/1889 (55%), Gaps = 15/1889 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V D E F+ +++ +V + + VT+ D NPPK+DKIEDM+ +T+L
Sbjct: 39 FVADPKESFVKATVQSREGGKVTAK-TEAGATVTVKEDQCFPMNPPKYDKIEDMAMMTHL 97
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 98 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFS 157
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A K
Sbjct: 158 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKK---------- 207
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
++P G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 208 EEPTSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIE 267
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPNV 981
YLLEKSRV Q + ERS+HIFYQI+ + E LL + +Y F+ IT+P++
Sbjct: 268 TYLLEKSRVTFQLKAERSYHIFYQIMSN-KKPDLIEMLLITTNPYDYAFVSQGEITVPSI 326
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
DD +E +T +++ I+GF DE SI ++ AV+ GNL+F Q+++ +QA V K
Sbjct: 327 DDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADK 386
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L GL +L KA PR+KVG EFV K Q EQ AV A+AKA Y+++F W+V RI
Sbjct: 387 AAYLQGLNSADLLKALCYPRVKVGNEFVTKGQTVEQVYNAVGALAKAVYDKMFLWMVARI 446
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 447 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL + H K
Sbjct: 506 KEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNN 565
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P + ++HF+++HYAG VDY+ WL KN DPLNE VVGL Q S+ +A +
Sbjct: 566 FQKPKPVKGKPEAHFSLIHYAGTVDYNITGWLDKNKDPLNETVVGLYQKSSVKTLALL-- 623
Query: 1870 DAEFAGICAAEMNETAFGMRSRKG-MFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNH 2046
F+G +A+ +KG F+TVS L +E L KLMT LR+T PHFVRCIIPN
Sbjct: 624 ---FSGPASADAEAGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNE 680
Query: 2047 EKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFID 2223
K G + LVL QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L IP+ FID
Sbjct: 681 TKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFID 740
Query: 2224 GKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLS 2403
K++ K++ ++DID Y+ G +KVFF+ G+L LEE RD KL +I QA+CRGFL+
Sbjct: 741 SKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQIITRTQARCRGFLA 800
Query: 2404 RRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELR 2583
R Y N A++ +++W W +L+ K+KPLL+ T+ E+ +E
Sbjct: 801 RVEYQRMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFE 860
Query: 2584 ATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEY 2763
TKE L K E +E E+K+ ++ E+ +Q Q+Q E+++ A+ ++ +L +LE
Sbjct: 861 KTKESLAKAEAKRKELEEKMVALMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEA 920
Query: 2764 IVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXX 2943
+ + +R +RK + + +K +
Sbjct: 921 KIKEATERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 980
Query: 2944 XXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQD 3123
+ L E++ KAK +LE Q+ +LE
Sbjct: 981 LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGS 1040
Query: 3124 LNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEE 3303
L +E++ + +LE+ KRKL +L+ +++ + ++L+ +L K++ E+ + ++ ++E
Sbjct: 1041 LEQEKKLRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDE 1100
Query: 3304 SANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEA 3483
A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L++ A
Sbjct: 1101 QALAMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEI-SERLEEAGGA 1159
Query: 3484 TMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQ 3660
T Q M++K E E +R +E+ E + K + V EL +QI+ ++ + +
Sbjct: 1160 TSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQK 1219
Query: 3661 LEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQ 3840
LEK++++ E D+A + + ++ +++K + E L E+++ E L Q
Sbjct: 1220 LEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLVNDLTGQ 1279
Query: 3841 LERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQL 4020
R + E +R +E++ + + R + K A + +
Sbjct: 1280 RARLQTEAGEYSRQLDEKDSLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSA 1339
Query: 4021 EDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEH 4200
+ + L ++ EE + +A L++ + A + R K E Q+ EEL + + +
Sbjct: 1340 RHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1399
Query: 4201 LQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEE 4371
LQ E E + + ++K+++Q E+ED +++E A+ +K+Q+ F+ ++E
Sbjct: 1400 LQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILSEW 1459
Query: 4372 RVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNK 4551
+ ++ + +A +E R T + + N + + LE R ++LQQE+ D
Sbjct: 1460 KHKYEETHAELEASQKESRSLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQI 1519
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAI 4731
+ GK +HELEK K+ +E E ++++ +EE E +L+ E LR+++ +KSE DR I
Sbjct: 1520 AEGGKRIHELEKVKKQIEQEKSEIQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKI 1579
Query: 4732 SNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLK 4911
+ KD E ++ +R ++ + ++ L+ E R ++ A+ +KK+E + E+E QL ANR+
Sbjct: 1580 AEKDEEIDQLKRNHVRVVETMQTMLDAEIRSRNDAIRIKKKMEGDLNEMEIQLNHANRMA 1639
Query: 4912 EEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLM 5091
E + Q+ ++A + +ED+ L +R+ ++AE E+LR E
Sbjct: 1640 AEALRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQTE 1699
Query: 5092 QARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQR 5262
++RK Q K++LE I+Q A +K +
Sbjct: 1700 RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQLQGEMEDIVQEAHNAEEKAK 1759
Query: 5263 KAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALE 5442
KA + +L E+ + E K++LE++ +D + ++ E E A + Q+ LE
Sbjct: 1760 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1819
Query: 5443 AKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNR 5622
A+V+ LE ++ E + A + R+ E+R+ + T Q E++++ + ++L++K K +
Sbjct: 1820 ARVRDLEGEVESEQKRNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQSKVK 1879
Query: 5623 NLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+RQ +EAE++ + +K R +Q E ++
Sbjct: 1880 AYKRQAEEAEEQSNVNLSKFRKIQHELEE 1908
Score = 159 bits (401), Expect = 1e-36
Identities = 192/918 (20%), Positives = 382/918 (40%), Gaps = 32/918 (3%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + + ++ L + + ELE+ L+ E D + + A+ + EE +
Sbjct: 850 KEMANMKEEFEKTKESLAKAEAKRKELEEKMVALMQEKNDLQLQVQAEADSLADAEERCD 909
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE N L K+ R ++ EL++D++ E
Sbjct: 910 QLIKTKIQLEAKIKEATERAEDEEEINAELTAKK-RKLEDECSELKKDIDD-------LE 961
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E L + +++ +E A + A +Q ++ +
Sbjct: 962 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1021
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIAL-LQASRADID 3750
+ + K K +QV++L +EQ KK R LE+ + + + + +AQE + ++ + +D
Sbjct: 1022 TLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGD-LKLAQESTMDIENDKQQLD 1080
Query: 3751 KKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLA 3930
+K K E + +Q+ + E ++ L QL++ EL R+ E EE A R
Sbjct: 1081 EKLKKKEFEMSNLQSKI----EDEQALAMQLQKKIKELQ--ARIEELEEEIEAERASRAK 1134
Query: 3931 TAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQ 4110
RL+ A + Q+E +++K EAE
Sbjct: 1135 AEKQRSDLSRELEEISERLEEAGGATSAQIE------MNKKREAE--------------- 1173
Query: 4111 GAGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELE 4281
+ RR EE+ Q LRKK+ V L +Q++ + K+++ + K +++ E++
Sbjct: 1174 -FQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID 1232
Query: 4282 DSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLN 4461
D + +E V + + EK + E Q++E + + ++ + +L + R L
Sbjct: 1233 DLASNMETVSKAKGNLEKMCRTLEDQLSELKSKEE----EQQRLVNDLTGQRAR---LQT 1285
Query: 4462 EVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE 4641
E L+E D + L + Q ++ + + E KAK +L L R +
Sbjct: 1286 EAGEYSRQLDEKDSLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSARHDCDL 1345
Query: 4642 LEDNLQIAEDARLRL---------EVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDL 4794
L + + ++A+ L EV K E+D AI + E EE ++ L ++++D
Sbjct: 1346 LREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETD-AIQRTE-ELEEAKKKLAQRLQDA 1403
Query: 4795 ENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIEC 4974
E +E + +++++N++ +L +E N E++ +
Sbjct: 1404 EEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILSEWKHKY 1463
Query: 4975 EEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGG 5154
EE E R + V+ E+ + E L + K A+GG
Sbjct: 1464 EETHAELEASQKESRSLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGG 1523
Query: 5155 GISSE---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQ 5325
E K+++E + ++ +++ E K + Q++L Q+ +++ +R + +
Sbjct: 1524 KRIHELEKVKKQIEQEKSEIQAALEEAEASLEHEEGKILRIQLELNQVKSEI--DRKIAE 1581
Query: 5326 KTEAEKQSLERSNRDYKAKITELESGAQSR--ARAQMAALEAKVQYLEDQLNVEGQEKTA 5499
K E Q R + T L++ +SR A +E + +E QLN +
Sbjct: 1582 KDEEIDQLKRNHVRVVETMQTMLDAEIRSRNDAIRIKKKMEGDLNEMEIQLNHANRMAAE 1641
Query: 5500 ANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTK 5679
A R R + L DT +D R E KE L + L+ +++E + +
Sbjct: 1642 ALRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQTERS 1701
Query: 5680 HRNVQREADDLLDANEQL 5733
+ ++E LLDA+E++
Sbjct: 1702 RKIAEQE---LLDASERV 1716
Score = 125 bits (315), Expect = 9e-27
Identities = 131/753 (17%), Positives = 314/753 (41%), Gaps = 42/753 (5%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + E+ + + + + +R +LE++ QE+ D+ ++ S AD ++
Sbjct: 849 EKEMANMKEEFEKTKESLAKAEAKRKELEEKMVALMQEKNDLQLQVQAEADSLADAEERC 908
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E + +E L + + DE L + ++ E A ++
Sbjct: 909 DQLIKTKIQLEAKIKEATERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 968
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ K A N+ + L +E L +E +K +
Sbjct: 969 KE---------------------KHATENKVKNLTEEMAGL----DETIAKLTKEKKALQ 1003
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
A Q + + E+ VN L + + K + V+ L+ LE+ + + + ++K+K++ +L
Sbjct: 1004 EAHQQTLDDLQAEEDKVNT-LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDL 1062
Query: 4279 ---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL 4449
++S+M++EN + D + ++K+FE + ++ ++AL + + +++++ + R+
Sbjct: 1063 KLAQESTMDIENDK-QQLDEKLKKKEFEMSNLQSKIEDEQALAMQ--LQKKIKELQARIE 1119
Query: 4450 SLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRV 4629
L E++ + ++++ R L +EL++ ++ G + + EAE MR
Sbjct: 1120 ELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR 1179
Query: 4630 QME----------------------ELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
+E EL + + + + +LE +K E D SN +
Sbjct: 1180 DLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNME 1239
Query: 4744 VEAEEKR------RGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANR 4905
++ K R L Q+ +L+++ E ++R + R +++ + GE +QL+ +
Sbjct: 1240 TVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLVNDLTGQRARLQTEAGEYSRQLDEKDS 1299
Query: 4906 LKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA----DRKFRAVEAEREQLRE 5073
L + E + + EE +AK +A L+ A D E E+E E
Sbjct: 1300 LVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSARHDCDLLREQYEEEQEAKAE 1359
Query: 5074 ANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAID 5253
+ +A + + E K++L ++ + C
Sbjct: 1360 LQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEK 1419
Query: 5254 KQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMA 5433
+++ Q ++E + D+ + ++++ ++ ++K K E + ++ ++ +
Sbjct: 1420 TKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILSEWKHKYEETHAELEA-SQKESR 1478
Query: 5434 ALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNL 5613
+L ++ +++ + R + L++ ++D T+Q + + + +++ ++
Sbjct: 1479 SLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKVKKQIEQ 1538
Query: 5614 KNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ ++ L+EAE + E K +Q E + +
Sbjct: 1539 EKSEIQAALEEAEASLEHEEGKILRIQLELNQV 1571
Score = 115 bits (288), Expect = 1e-23
Identities = 173/890 (19%), Positives = 354/890 (39%), Gaps = 113/890 (12%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ +E + +E+D ++ ++KL + E + +Q +++ E + +L LQ
Sbjct: 1056 RKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDEQALAMQLQKKIKELQ 1115
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + +R S R ++E + + +
Sbjct: 1116 ARIEELEEEIE--AERASRAKAEKQRSDLSR--ELEEISERLEEAGGATSAQIEMNKKRE 1171
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K ++
Sbjct: 1172 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELG---EQIDNLQRVKQKLEKEKSEMK 1228
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K LE+ R L +L + K E+ V +L Q + E
Sbjct: 1229 MEIDDLASNMETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLVNDLTGQRARLQTEAG 1288
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ DE+ + V+ + + + I+EL+ +E E A++ + + ++
Sbjct: 1289 EYSRQLDEKDSLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSARHDCDLLRE 1348
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
++ + LQ MS+ + EV TK + IQ T E +EE K K ++++++ +
Sbjct: 1349 QYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQDAEEH 1406
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME-------I 3789
+E + + LEK + + E D+ ++ A+ A +DKK++ + L E
Sbjct: 1407 VEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILSEWKHKYEET 1466
Query: 3790 QANLAESDEHKRTLIDQL-------ERSRDELDHLNRVREEEE----------------- 3897
A L S + R+L +L E S D+L+ L R + +
Sbjct: 1467 HAELEASQKESRSLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRI 1526
Query: 3898 HAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRAR----QLEDEKNALLDEKEE-- 4059
H +++++ + I R + Q++ E + + EK+E
Sbjct: 1527 HELEKVKKQIEQEKSEIQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEI 1586
Query: 4060 ----------AEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN------LRD 4191
E ++ L+ EI + R A ++K E +N+ +L N LR+
Sbjct: 1587 DQLKRNHVRVVETMQTMLDAEIRS-RNDAIRIKKKMEGDLNEMEIQLNHANRMAAEALRN 1645
Query: 4192 VEHLQKQLEESEVAKERILQSKKKIQQELEDSSM-------ELENVRASHRDSEKRQKKF 4350
+ Q L+++++ + L+ ++ ++++L E+E +RA+ +E+ +K
Sbjct: 1646 YRNTQGILKDTQLHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIA 1705
Query: 4351 ESQM--AEERVAV----------QKALLDRDAMS---------QELRDRETRVLSLLNEV 4467
E ++ A ERV + K L+ D QE + E + + +
Sbjct: 1706 EQELLDASERVQLLHTQNTSLINTKKKLETDISQLQGEMEDIVQEAHNAEEKAKKAITDA 1765
Query: 4468 DIMKEHLEES-------DRVRRSLQQELQDSISNKDDFG--------KNVHELEKAKRSL 4602
+M E L++ +R++++L+Q ++D D+ K + +LE R L
Sbjct: 1766 AMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRDL 1825
Query: 4603 EAELNDMRVQMEELEDNL------------QIAEDAR--LRLEVTNQALKSESDRAISNK 4740
E E+ + + E L Q ED + LRL+ L+S+ +A +
Sbjct: 1826 EGEVESEQKRNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQSKV-KAYKRQ 1884
Query: 4741 DVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
EAEE+ L + R +++ELE + A S K+ + E+ ++
Sbjct: 1885 AEEAEEQSNVNLSKFRKIQHELEEAEERADIAESQVNKLRVKSREVHTKI 1934
Score = 75.1 bits (183), Expect = 2e-11
Identities = 109/521 (20%), Positives = 197/521 (36%), Gaps = 18/521 (3%)
Frame = +1
Query: 4234 KERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAM 4413
K + L + ++E+ + E E + S +E ++K+ E +M L A
Sbjct: 838 KIKPLLKSAETEKEMANMKEEFEKTKESLAKAEAKRKELEEKMVALMQEKNDLQLQVQAE 897
Query: 4414 SQELRDRETRVLSLLN-------EVDIMKEHLEESDRV-------RRSLQQELQDSISNK 4551
+ L D E R L+ ++ E E+ + + +R L+ E + +
Sbjct: 898 ADSLADAEERCDQLIKTKIQLEAKIKEATERAEDEEEINAELTAKKRKLEDECSELKKDI 957
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQA----LKSES 4719
DD + ++EK K + E ++ ++ +M L++ + + L+ +Q L++E
Sbjct: 958 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1017
Query: 4720 DRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
D+ N +A+ K L +Q+ DLE LE EK+ R +E +LE L++A
Sbjct: 1018 DKV--NTLTKAKTK---LEQQVDDLEGSLEQEKK-------LRMDLERAKRKLEGDLKLA 1065
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREAN 5079
+ + + E + ED AL + +K + ++A E+L E
Sbjct: 1066 QESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDEQALAMQLQKKIKELQARIEELEEEI 1125
Query: 5080 EGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQ 5259
E RAK S+ R LE
Sbjct: 1126 EA--------------ERASRAKAEKQRSDLSRELE------------------------ 1147
Query: 5260 RKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAAL 5439
+ +LE+ S + +N+K EAE Q + R +LE A + A AAL
Sbjct: 1148 -EISERLEEAGGATSAQIEMNKKREAEFQKMRR----------DLEE-ATLQHEATAAAL 1195
Query: 5440 EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKN 5619
K D + G++ R ++LEK ++ + +D +E +
Sbjct: 1196 RKK---HADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDD-------LASNMETVSKAK 1245
Query: 5620 RNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
NL + ED++S ++K QR +DL +L E
Sbjct: 1246 GNLEKMCRTLEDQLSELKSKEEEQQRLVNDLTGQRARLQTE 1286
>gi|38091413|ref|XP_354615.1| myosin, heavy polypeptide 1, skeletal
muscle, adult [Mus musculus]
Length = 1942
Score = 1116 bits (2886), Expect = 0.0
Identities = 649/1888 (34%), Positives = 1050/1888 (55%), Gaps = 14/1888 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V D E F+ +++ +V + + VT+ D V NPPK+DKIEDM+ +T+L
Sbjct: 39 FVVDAKESFVKATVQSREGGKVTAK-TEGGTTVTVKDDQVYPMNPPKYDKIEDMAMMTHL 97
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 98 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRQEAPPHIFS 157
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A K A + +
Sbjct: 158 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEATSGK--- 214
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 215 -------MQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIE 267
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPNV 981
YLLEKSRV Q + ERS+HIFYQI+ + E LL + +Y F+ IT+P++
Sbjct: 268 TYLLEKSRVTFQLKAERSYHIFYQIMSN-KKPDLIEMLLITTNPYDYAFVSQGEITVPSI 326
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
DD +E +T +++ I+GF DE SI ++ AV+ GN++F Q+++ +QA V K
Sbjct: 327 DDQEELMATDSAIDILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADK 386
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L L +L KA PR+KVG E+V K Q +Q +V A+AKA YE++F W+VTRI
Sbjct: 387 AAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNSVGALAKAVYEKMFLWMVTRI 446
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 447 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL + H K
Sbjct: 506 KEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNN 565
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P + ++HF++VHYAG VDY+ WL KN DPLNE VVGL Q S+ +A ++
Sbjct: 566 FQKPKPAKGKVEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSMKTLAYLFS 625
Query: 1870 DAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHE 2049
A A + G + + F+TVS L +E L KLMT LR+T PHFVRCIIPN
Sbjct: 626 GAAAAAEAESGGGGGKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 685
Query: 2050 KKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDG 2226
K G + LVL QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L IP+ FID
Sbjct: 686 KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDS 745
Query: 2227 KESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSR 2406
K++ K++ ++DID Y+ G +KVFF+ G+L LEE RD KL LI QA CRG+L+R
Sbjct: 746 KKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQAMCRGYLAR 805
Query: 2407 RLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRA 2586
Y N A++ +++W W +L+ K+KPLL+ T+ E+ +E
Sbjct: 806 VEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFEK 865
Query: 2587 TKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYI 2766
KE L K E +E E+K+ ++ E+ +Q Q+Q E+++ A+ ++ +L +LE
Sbjct: 866 AKENLAKAEAKRKELEEKMVALMQEKNDLQLQVQSEADSLADAEERCDQLIKTKIQLEAK 925
Query: 2767 VNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXX 2946
+ ++ +R +RK + + +K +
Sbjct: 926 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 985
Query: 2947 XXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDL 3126
+ L E++ KAK +LE Q+ +LE L
Sbjct: 986 TEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSL 1045
Query: 3127 NRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEES 3306
+E++ + +LE+ KRKL +L+ +++ + ++L+ +L K++ E+ + ++ ++E
Sbjct: 1046 EQEKKIRMDLERAKRKLEGDLKLAQESTMDVENDKQQLDEKLKKKEFEMSNLQSKIEDEQ 1105
Query: 3307 ANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT 3486
A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L++ AT
Sbjct: 1106 ALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEI-SERLEEAGGAT 1164
Query: 3487 MLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQL 3663
Q M++K E E +R +E+ E + K + V EL +QI+ ++ + +L
Sbjct: 1165 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1224
Query: 3664 EKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQL 3843
EK++++ E D+A + ++ S+ +++K + E + E++ E L Q
Sbjct: 1225 EKEKSEMKMEIDDLASNMEVISKSKGNLEKMCRTLEDQVSELKTKEEEQQRLINELTAQR 1284
Query: 3844 ERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLE 4023
R + E +R +E++ + + R + K A + +
Sbjct: 1285 GRLQTESGEYSRQLDEKDSLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSR 1344
Query: 4024 DEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHL 4203
+ + L ++ EE + +A L++ + A + R K E Q+ EEL + + + L
Sbjct: 1345 HDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1404
Query: 4204 QKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEER 4374
Q E E + + ++K+++Q E+ED +++E A+ +K+Q+ F+ +AE +
Sbjct: 1405 QDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWK 1464
Query: 4375 VAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKD 4554
++ + +A +E R T + + N + +HLE R ++LQQE+ D
Sbjct: 1465 QKYEETHAELEASQKESRSLSTELFKIKNAYEESLDHLETLKRENKNLQQEISDLTEQIA 1524
Query: 4555 DFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAIS 4734
+ GK +HELEK K+ +E E ++++ +EE E +L+ E LR+++ +KSE DR I+
Sbjct: 1525 EGGKRIHELEKIKKQIEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKIA 1584
Query: 4735 NKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKE 4914
KD E ++ +R ++ + +++ L+ E R ++ A+ +KK+E + E+E QL +NR+
Sbjct: 1585 EKDEEIDQLKRNHIRVVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHSNRMAA 1644
Query: 4915 EYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQ 5094
E + Q+ ++A + +ED+ L +R+ ++AE E+LR E +
Sbjct: 1645 EALRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1704
Query: 5095 ARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRK 5265
+RK Q K++LE I+Q A +K +K
Sbjct: 1705 SRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKK 1764
Query: 5266 AQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEA 5445
A + +L E+ + E K++LE++ +D + ++ E E A + Q+ LEA
Sbjct: 1765 AITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEA 1824
Query: 5446 KVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRN 5625
+V+ LE ++ E + A + R+ E+R+ + T Q E++++ + ++L++K K +
Sbjct: 1825 RVRELEGEVENEQKRNVEAIKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQSKVKA 1884
Query: 5626 LRRQLDEAEDEMSRERTKHRNVQREADD 5709
+RQ +EAE++ + K R +Q E ++
Sbjct: 1885 YKRQAEEAEEQSNVNLAKFRKIQHELEE 1912
Score = 155 bits (392), Expect = 1e-35
Identities = 191/918 (20%), Positives = 384/918 (41%), Gaps = 32/918 (3%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + + +++L + + ELE+ L+ E D + + A+ + EE +
Sbjct: 854 KEMANMKEEFEKAKENLAKAEAKRKELEEKMVALMQEKNDLQLQVQSEADSLADAEERCD 913
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE N L K+ R ++ EL++D++ E
Sbjct: 914 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKDIDD-------LE 965
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E L + +++ +E A + A +Q ++ +
Sbjct: 966 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1025
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIAL-LQASRADID 3750
+ + K K +QV++L +EQ KK R LE+ + + + + +AQE + ++ + +D
Sbjct: 1026 TLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGD-LKLAQESTMDVENDKQQLD 1084
Query: 3751 KKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLA 3930
+K K E + +Q+ + E ++ L QL++ EL R+ E EE A R
Sbjct: 1085 EKLKKKEFEMSNLQSKI----EDEQALGMQLQKKIKELQ--ARIEELEEEIEAERASRAK 1138
Query: 3931 TAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQ 4110
RL+ A + Q+E +++K EAE
Sbjct: 1139 AEKQRSDLSRELEEISERLEEAGGATSAQIE------MNKKREAE--------------- 1177
Query: 4111 GAGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELE 4281
+ RR EE+ Q LRKK+ V L +Q++ + K+++ + K +++ E++
Sbjct: 1178 -FQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID 1236
Query: 4282 DSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLN 4461
D + +E + S + EK + E Q++E + + ++ + EL + R L
Sbjct: 1237 DLASNMEVISKSKGNLEKMCRTLEDQVSELKTKEE----EQQRLINELTAQRGR---LQT 1289
Query: 4462 EVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE 4641
E L+E D + L + Q ++ + + E KAK +L L R +
Sbjct: 1290 ESGEYSRQLDEKDSLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDL 1349
Query: 4642 LEDNLQIAEDARLRL---------EVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDL 4794
L + + ++A+ L EV K E+D AI + E EE ++ L ++++D
Sbjct: 1350 LREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETD-AIQRTE-ELEEAKKKLAQRLQDA 1407
Query: 4795 ENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIEC 4974
E +E + +++++N++ +L +E N E++ +
Sbjct: 1408 EEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKY 1467
Query: 4975 EEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGG 5154
EE E R + ++ E+ + E L + K A+GG
Sbjct: 1468 EETHAELEASQKESRSLSTELFKIKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGG 1527
Query: 5155 GISSE---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQ 5325
E K+++E + ++ +++ E K + Q++L Q+ +++ +R + +
Sbjct: 1528 KRIHELEKIKKQIEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEI--DRKIAE 1585
Query: 5326 KTEAEKQSLERSNRDYKAKITELESGAQSR--ARAQMAALEAKVQYLEDQLNVEGQEKTA 5499
K E Q R ++ + L++ +SR A +E + +E QLN +
Sbjct: 1586 KDEEIDQLKRNHIRVVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHSNRMAAE 1645
Query: 5500 ANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTK 5679
A R R + L DT +D R E KE L + L+ +++E + +
Sbjct: 1646 ALRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQTERS 1705
Query: 5680 HRNVQREADDLLDANEQL 5733
+ ++E LLDA+E++
Sbjct: 1706 RKIAEQE---LLDASERV 1720
Score = 125 bits (314), Expect = 1e-26
Identities = 132/753 (17%), Positives = 314/753 (41%), Gaps = 42/753 (5%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + E+ + + + + +R +LE++ QE+ D+ ++ S AD ++
Sbjct: 853 EKEMANMKEEFEKAKENLAKAEAKRKELEEKMVALMQEKNDLQLQVQSEADSLADAEERC 912
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ + +E L + + DE L + ++ E A ++
Sbjct: 913 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 972
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ K A N+ + L +E L +E +K +
Sbjct: 973 KE---------------------KHATENKVKNLTEEMAGL----DETIAKLTKEKKALQ 1007
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
A Q + + E+ VN L + + K + V+ L+ LE+ + + + ++K+K++ +L
Sbjct: 1008 EAHQQTLDDLQAEEDKVNT-LTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDL 1066
Query: 4279 ---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL 4449
++S+M++EN + D + ++K+FE + ++ ++AL + +++++ + R+
Sbjct: 1067 KLAQESTMDVENDK-QQLDEKLKKKEFEMSNLQSKIEDEQAL--GMQLQKKIKELQARIE 1123
Query: 4450 SLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRV 4629
L E++ + ++++ R L +EL++ ++ G + + EAE MR
Sbjct: 1124 ELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR 1183
Query: 4630 QME----------------------ELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
+E EL + + + + +LE +K E D SN +
Sbjct: 1184 DLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNME 1243
Query: 4744 VEAEEKR------RGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANR 4905
V ++ K R L Q+ +L+ + E ++R + + R +++ + GE +QL+ +
Sbjct: 1244 VISKSKGNLEKMCRTLEDQVSELKTKEEEQQRLINELTAQRGRLQTESGEYSRQLDEKDS 1303
Query: 4906 LKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLR----EADRKFRAVEAEREQLRE 5073
L + E + + EE +AK +A L+ + D E E+E E
Sbjct: 1304 LVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAE 1363
Query: 5074 ANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAID 5253
+ +A + + E K++L ++ + C
Sbjct: 1364 LQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEK 1423
Query: 5254 KQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMA 5433
+++ Q ++E + D+ + ++++ ++ ++K K E + ++ ++ +
Sbjct: 1424 TKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKYEETHAELEA-SQKESR 1482
Query: 5434 ALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNL 5613
+L ++ +++ R + L++ ++D T+Q + + + +++ ++
Sbjct: 1483 SLSTELFKIKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQIEQ 1542
Query: 5614 KNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ L+ L+EAE + E K +Q E + +
Sbjct: 1543 EKSELQAALEEAEASLEHEEGKILRIQLELNQV 1575
Score = 117 bits (294), Expect = 3e-24
Identities = 177/894 (19%), Positives = 361/894 (39%), Gaps = 117/894 (13%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ +E + +E+D ++ ++KL + E + +Q +++ E +L LQ
Sbjct: 1060 RKLEGDLKLAQESTMDVENDKQQLDEKLKKKEFEMSNLQSKIEDEQALGMQLQKKIKELQ 1119
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + +R S R ++E + + +
Sbjct: 1120 ARIEELEEEIE--AERASRAKAEKQRSDLSR--ELEEISERLEEAGGATSAQIEMNKKRE 1175
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K ++
Sbjct: 1176 AEFQKMRRDLEEATLQHEATAATLRKKHADSVAELG---EQIDNLQRVKQKLEKEKSEMK 1232
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K LE K+ LED L K + + L N+L + LQ
Sbjct: 1233 MEIDDLASNMEVISKSKGNLE----KMCRTLEDQVSELKTKEEEQQRLINELTAQRGRLQ 1288
Query: 3277 HQLTRY----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLE 3444
+ Y DE+ + V+ + + + I+EL+ +E E A++ + +
Sbjct: 1289 TESGEYSRQLDEKDSLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCD 1348
Query: 3445 KVKGDVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEE 3618
++ ++ + LQ MS+ + EV TK + IQ T E +EE K K ++++++
Sbjct: 1349 LLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQD 1406
Query: 3619 LHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME---- 3786
+ +E + + LEK + + E D+ ++ A+ A +DKK++ + L E
Sbjct: 1407 AEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQK 1466
Query: 3787 ---IQANLAESDEHKRTLIDQLERSR----DELDHLNRVREEEE---------------- 3897
A L S + R+L +L + + + LDHL ++ E +
Sbjct: 1467 YEETHAELEASQKESRSLSTELFKIKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEG 1526
Query: 3898 ----HAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRAR----QLEDEKNALLDEK 4053
H +++++ + I R + Q++ E + + EK
Sbjct: 1527 GKRIHELEKIKKQIEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEK 1586
Query: 4054 EE------------AEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN----- 4182
+E E +++ L+ EI + R A ++K E +N+ +L N
Sbjct: 1587 DEEIDQLKRNHIRVVESMQSTLDAEIRS-RNDAIRLKKKMEGDLNEMEIQLNHSNRMAAE 1645
Query: 4183 -LRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSM-------ELENVRASHRDSEKR 4338
LR+ + Q L+++++ + L+ ++ ++++L E+E +RA+ +E+
Sbjct: 1646 ALRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQTERS 1705
Query: 4339 QKKFESQM--AEERVAV----------QKALLDRDAMS---------QELRDRETRVLSL 4455
+K E ++ A ERV + K L+ D QE R+ E +
Sbjct: 1706 RKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKA 1765
Query: 4456 LNEVDIMKEHLEES-------DRVRRSLQQELQDSISNKDDFG--------KNVHELEKA 4590
+ + +M E L++ +R++++L+Q ++D D+ K + +LE
Sbjct: 1766 ITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEAR 1825
Query: 4591 KRSLEAEL-NDMRVQMEEL-----------EDNLQIAEDAR--LRLEVTNQALKSESDRA 4728
R LE E+ N+ + +E + E Q ED + LRL+ L+S+ +A
Sbjct: 1826 VRELEGEVENEQKRNVEAIKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQSKV-KA 1884
Query: 4729 ISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
+ EAEE+ L + R +++ELE + A S K+ + E+ ++
Sbjct: 1885 YKRQAEEAEEQSNVNLAKFRKIQHELEEAEERADIAESQVNKLRVKSREVHTKI 1938
Score = 70.1 bits (170), Expect = 6e-10
Identities = 91/453 (20%), Positives = 190/453 (41%), Gaps = 36/453 (7%)
Frame = +1
Query: 4492 ESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAE- 4668
E+++ ++++E + + N ELE+ +L E ND+++Q++ D+L AE
Sbjct: 851 ETEKEMANMKEEFEKAKENLAKAEAKRKELEEKMVALMQEKNDLQLQVQSEADSLADAEE 910
Query: 4669 --DARLRLEVTNQA-LKSESDRAISNKDVEAE--EKRRGLLKQIRDLENELENEKRGKSG 4833
D ++ ++ +A +K ++RA +++ AE K+R L + +L+ ++++ + +
Sbjct: 911 RCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAK 970
Query: 4834 AVSHRKKIENQIGELEQQL----EVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKED 5001
+ EN++ L +++ E +L +E + Q E ++ +
Sbjct: 971 VEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKA 1030
Query: 5002 IAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRR 5181
L ++ D +E EQ ++ L +A+++ +K++
Sbjct: 1031 KIKLEQQVD----DLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMD----VENDKQQ 1082
Query: 5182 LEAKIAQXXXXXXXXQSNCE----LAIDKQRK---AQVQLEQITTDLSMERTLNQKTEAE 5340
L+ K+ + QS E L + Q+K Q ++E++ ++ ER K E +
Sbjct: 1083 LDEKLKKKEFEMSNLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQ 1142
Query: 5341 KQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRA-AR 5517
+ L R + ++ E GA S EA+ Q + L +E T + A A
Sbjct: 1143 RSDLSRELEEISERLEE-AGGATSAQIEMNKKREAEFQKMRRDL----EEATLQHEATAA 1197
Query: 5518 RLEKRLNDTTQQFEDEKRANEQAKELLEK-------------SNLK-----NRNLRRQLD 5643
L K+ D+ + ++ ++ K+ LEK SN++ NL +
Sbjct: 1198 TLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMEVISKSKGNLEKMCR 1257
Query: 5644 EAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
ED++S +TK QR ++L +L E
Sbjct: 1258 TLEDQVSELKTKEEEQQRLINELTAQRGRLQTE 1290
>gi|34870884|ref|XP_213345.2| similar to Myosin heavy chain, skeletal
muscle, adult 1 (Myosin heavy chain IIx/d) (MyHC-IIx/d)
[Rattus norvegicus]
Length = 1942
Score = 1115 bits (2884), Expect = 0.0
Identities = 650/1888 (34%), Positives = 1050/1888 (55%), Gaps = 14/1888 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V D E F+ +++ +V + + VT+ D V NPPK+DKIEDM+ +T+L
Sbjct: 39 FVVDAKESFVKATVQSREGGKVTAK-TEGGATVTVKDDQVFPMNPPKYDKIEDMAMMTHL 97
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 98 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRQEAPPHIFS 157
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A K A + +
Sbjct: 158 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEAPSGK--- 214
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 215 -------MQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIE 267
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPNV 981
YLLEKSRV Q + ERS+HIFYQI+ + E LL + +Y F+ IT+P++
Sbjct: 268 TYLLEKSRVTFQLKAERSYHIFYQIMSN-KKPDLIEMLLITTNPYDYAFVSQGEITVPSI 326
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
DD +E +T +++ I+GF DE SI ++ AV+ GN++F Q+++ +QA V K
Sbjct: 327 DDQEELMATDSAIDILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADK 386
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L L +L KA PR+KVG E+V K Q +Q AV A+AKA YE++F W+VTRI
Sbjct: 387 AAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRI 446
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 447 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL + H K
Sbjct: 506 KEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNN 565
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P + ++HF++VHYAG VDY+ WL KN DPLNE VVGL Q S+ +A ++
Sbjct: 566 FQKPKPAKGKVEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSMKTLAYLFS 625
Query: 1870 DAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHE 2049
A A + G + + F+TVS L +E L KLMT LR+T PHFVRCIIPN
Sbjct: 626 GAAAAAEAESGGGGGKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 685
Query: 2050 KKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDG 2226
K G + LVL QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L IP+ FID
Sbjct: 686 KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDS 745
Query: 2227 KESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSR 2406
K++ K++ ++DID Y+ G +KVFF+ G+L LEE RD KL LI QA CRG+L+R
Sbjct: 746 KKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQAMCRGYLAR 805
Query: 2407 RLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRA 2586
Y N A++ +++W W +L+ K+KPLL+ T+ E+ +E
Sbjct: 806 VEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFEK 865
Query: 2587 TKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYI 2766
TKE L K E +E E+K+ ++ E+ +Q Q+Q E+++ A+ ++ +L +LE
Sbjct: 866 TKENLAKAEAKRKELEEKMVALMQEKNDLQLQVQSEADSLADAEERCDQLIKTKIQLEAK 925
Query: 2767 VNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXX 2946
+ ++ +R +RK + + +K +
Sbjct: 926 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 985
Query: 2947 XXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDL 3126
+ L E++ KAK +LE Q+ +LE L
Sbjct: 986 TEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSL 1045
Query: 3127 NRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEES 3306
+E++ + +LE+ KRKL +L+ +++ + ++L+ +L K++ E+ + ++ ++E
Sbjct: 1046 EQEKKIRMDLERAKRKLEGDLKLAQESTMDVENDKQQLDEKLKKKEFEMSNLQSKIEDEQ 1105
Query: 3307 ANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT 3486
A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L++ AT
Sbjct: 1106 ALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEI-SERLEEAGGAT 1164
Query: 3487 MLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQL 3663
Q M++K E E +R +E+ E + K + V EL +QI+ ++ + +L
Sbjct: 1165 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1224
Query: 3664 EKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQL 3843
EK++++ E D+A + ++ S+ +++K + E + E++ E L Q
Sbjct: 1225 EKEKSEMKMEIDDLASNMEVISKSKGNLEKMCRTLEDQVSELKTKEEEQQRLINELTAQR 1284
Query: 3844 ERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLE 4023
R + E +R +E++ + + R + K A + +
Sbjct: 1285 GRLQTESGEYSRQLDEKDSLVSQLSRGKQAFTQQIEELKRQLEEEVKAKSALAHALQSSR 1344
Query: 4024 DEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHL 4203
+ + L ++ EE + +A L++ + A + R K E Q+ EEL + + + L
Sbjct: 1345 HDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1404
Query: 4204 QKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEER 4374
Q E E + + ++K+++Q E+ED +++E A+ +K+Q+ F+ +AE +
Sbjct: 1405 QDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWK 1464
Query: 4375 VAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKD 4554
++ + +A +E R T + + N + + LE R ++LQQE+ D
Sbjct: 1465 QKYEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIA 1524
Query: 4555 DFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAIS 4734
+ GK +HELEK K+ +E E ++++ +EE E +L+ E LR+++ +KSE DR I+
Sbjct: 1525 EGGKRIHELEKIKKQIEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKIA 1584
Query: 4735 NKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKE 4914
KD E ++ +R ++ + +++ L+ E R ++ A+ +KK+E + E+E QL +NR+
Sbjct: 1585 EKDEEIDQLKRNHIRVVESMQSTLDAEIRSRNDAIRIKKKMEGDLNEMEIQLNHSNRMAA 1644
Query: 4915 EYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQ 5094
E + Q+ ++A + +ED+ L +R+ ++AE E+LR E +
Sbjct: 1645 EALRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1704
Query: 5095 ARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRK 5265
+RK Q K++LE I+Q A +K +K
Sbjct: 1705 SRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKK 1764
Query: 5266 AQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEA 5445
A + +L E+ + E K++LE++ +D + ++ E E A + Q+ LEA
Sbjct: 1765 AITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEA 1824
Query: 5446 KVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRN 5625
+V+ LE ++ E + A + R+ E+R+ + T Q E++++ + ++L++K K +
Sbjct: 1825 RVRELEGEVENEQKRNVEAIKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQSKVKA 1884
Query: 5626 LRRQLDEAEDEMSRERTKHRNVQREADD 5709
+RQ +EAE++ + K R +Q E ++
Sbjct: 1885 YKRQAEEAEEQSNVNLAKFRKIQHELEE 1912
Score = 156 bits (394), Expect = 7e-36
Identities = 187/922 (20%), Positives = 386/922 (41%), Gaps = 36/922 (3%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + + +++L + + ELE+ L+ E D + + A+ + EE +
Sbjct: 854 KEMANMKEEFEKTKENLAKAEAKRKELEEKMVALMQEKNDLQLQVQSEADSLADAEERCD 913
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE N L K+ R ++ EL++D++ E
Sbjct: 914 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKDIDD-------LE 965
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E L + +++ +E A + A +Q ++ +
Sbjct: 966 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1025
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIAL-LQASRADID 3750
+ + K K +QV++L +EQ KK R LE+ + + + + +AQE + ++ + +D
Sbjct: 1026 TLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGD-LKLAQESTMDVENDKQQLD 1084
Query: 3751 KKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLA 3930
+K K E + +Q+ + E ++ L QL++ EL R+ E EE A R
Sbjct: 1085 EKLKKKEFEMSNLQSKI----EDEQALGMQLQKKIKELQ--ARIEELEEEIEAERASRAK 1138
Query: 3931 TAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQ 4110
RL+ A + Q+E +++K EAE
Sbjct: 1139 AEKQRSDLSRELEEISERLEEAGGATSAQIE------MNKKREAE--------------- 1177
Query: 4111 GAGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELE 4281
+ RR EE+ Q LRKK+ V L +Q++ + K+++ + K +++ E++
Sbjct: 1178 -FQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID 1236
Query: 4282 DSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLN 4461
D + +E + S + EK + E Q++E + + ++ + EL + R L
Sbjct: 1237 DLASNMEVISKSKGNLEKMCRTLEDQVSELKTKEE----EQQRLINELTAQRGR---LQT 1289
Query: 4462 EVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE 4641
E L+E D + L + Q ++ + + E KAK +L L R +
Sbjct: 1290 ESGEYSRQLDEKDSLVSQLSRGKQAFTQQIEELKRQLEEEVKAKSALAHALQSSRHDCDL 1349
Query: 4642 LEDNLQIAEDARLRL---------EVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDL 4794
L + + ++A+ L EV K E+D AI + E EE ++ L ++++D
Sbjct: 1350 LREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETD-AIQRTE-ELEEAKKKLAQRLQDA 1407
Query: 4795 ENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIEC 4974
E +E + +++++N++ +L +E N E++ +
Sbjct: 1408 EEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKY 1467
Query: 4975 EEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGG 5154
EE E R + ++ E+ + E L + K A+GG
Sbjct: 1468 EETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGG 1527
Query: 5155 GISSE---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQ 5325
E K+++E + ++ +++ E K + Q++L Q+ ++ +++
Sbjct: 1528 KRIHELEKIKKQIEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSE------IDR 1581
Query: 5326 KTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAA------LEAKVQYLEDQLNVEGQ 5487
K + + +++ R++ + ++S + R++ A +E + +E QLN +
Sbjct: 1582 KIAEKDEEIDQLKRNHIRVVESMQSTLDAEIRSRNDAIRIKKKMEGDLNEMEIQLNHSNR 1641
Query: 5488 EKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSR 5667
A R R + L DT +D R E KE L + L+ +++E + +
Sbjct: 1642 MAAEALRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQ 1701
Query: 5668 ERTKHRNVQREADDLLDANEQL 5733
+ ++E LLDA+E++
Sbjct: 1702 TERSRKIAEQE---LLDASERV 1720
Score = 126 bits (316), Expect = 7e-27
Identities = 132/753 (17%), Positives = 315/753 (41%), Gaps = 42/753 (5%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + E+ + + + + +R +LE++ QE+ D+ ++ S AD ++
Sbjct: 853 EKEMANMKEEFEKTKENLAKAEAKRKELEEKMVALMQEKNDLQLQVQSEADSLADAEERC 912
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ + +E L + + DE L + ++ E A ++
Sbjct: 913 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 972
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ K A N+ + L +E L +E +K +
Sbjct: 973 KE---------------------KHATENKVKNLTEEMAGL----DETIAKLTKEKKALQ 1007
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
A Q + + E+ VN L + + K + V+ L+ LE+ + + + ++K+K++ +L
Sbjct: 1008 EAHQQTLDDLQAEEDKVNT-LTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDL 1066
Query: 4279 ---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL 4449
++S+M++EN + D + ++K+FE + ++ ++AL + +++++ + R+
Sbjct: 1067 KLAQESTMDVENDK-QQLDEKLKKKEFEMSNLQSKIEDEQAL--GMQLQKKIKELQARIE 1123
Query: 4450 SLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRV 4629
L E++ + ++++ R L +EL++ ++ G + + EAE MR
Sbjct: 1124 ELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR 1183
Query: 4630 QME----------------------ELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
+E EL + + + + +LE +K E D SN +
Sbjct: 1184 DLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNME 1243
Query: 4744 VEAEEKR------RGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANR 4905
V ++ K R L Q+ +L+ + E ++R + + R +++ + GE +QL+ +
Sbjct: 1244 VISKSKGNLEKMCRTLEDQVSELKTKEEEQQRLINELTAQRGRLQTESGEYSRQLDEKDS 1303
Query: 4906 LKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLR----EADRKFRAVEAEREQLRE 5073
L + E + + EE +AK +A L+ + D E E+E E
Sbjct: 1304 LVSQLSRGKQAFTQQIEELKRQLEEEVKAKSALAHALQSSRHDCDLLREQYEEEQEAKAE 1363
Query: 5074 ANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAID 5253
+ +A + + E K++L ++ + C
Sbjct: 1364 LQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEK 1423
Query: 5254 KQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMA 5433
+++ Q ++E + D+ + ++++ ++ ++K K E + ++ ++ +
Sbjct: 1424 TKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKYEETHAELEA-SQKESR 1482
Query: 5434 ALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNL 5613
+L ++ +++ + R + L++ ++D T+Q + + + +++ ++
Sbjct: 1483 SLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQIEQ 1542
Query: 5614 KNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ L+ L+EAE + E K +Q E + +
Sbjct: 1543 EKSELQAALEEAEASLEHEEGKILRIQLELNQV 1575
Score = 117 bits (293), Expect = 3e-24
Identities = 180/894 (20%), Positives = 361/894 (40%), Gaps = 117/894 (13%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ +E + +E+D ++ ++KL + E + +Q +++ E +L LQ
Sbjct: 1060 RKLEGDLKLAQESTMDVENDKQQLDEKLKKKEFEMSNLQSKIEDEQALGMQLQKKIKELQ 1119
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + +R S R ++E + + +
Sbjct: 1120 ARIEELEEEIE--AERASRAKAEKQRSDLSR--ELEEISERLEEAGGATSAQIEMNKKRE 1175
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K ++
Sbjct: 1176 AEFQKMRRDLEEATLQHEATAATLRKKHADSVAELG---EQIDNLQRVKQKLEKEKSEMK 1232
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K LE K+ LED L K + + L N+L + LQ
Sbjct: 1233 MEIDDLASNMEVISKSKGNLE----KMCRTLEDQVSELKTKEEEQQRLINELTAQRGRLQ 1288
Query: 3277 HQLTRY----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLE 3444
+ Y DE+ + V+ + + + I+EL+ +E E A++ + +
Sbjct: 1289 TESGEYSRQLDEKDSLVSQLSRGKQAFTQQIEELKRQLEEEVKAKSALAHALQSSRHDCD 1348
Query: 3445 KVKGDVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEE 3618
++ ++ + LQ MS+ + EV TK + IQ T E +EE K K ++++++
Sbjct: 1349 LLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQD 1406
Query: 3619 LHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME---- 3786
+ +E + + LEK + + E D+ ++ A+ A +DKK++ + L E
Sbjct: 1407 AEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQK 1466
Query: 3787 ---IQANLAESDEHKRTLIDQL-------ERSRDELDHLNRVREEEEHAFANMQRRLAT- 3933
A L S + R+L +L E S D+L+ L R + + +++ ++A
Sbjct: 1467 YEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG 1526
Query: 3934 ----------------------AXXXXXXXXXXXXXXTRLKIA-NINRARQLEDEKNALL 4044
A L+I +N+ + D K A
Sbjct: 1527 GKRIHELEKIKKQIEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEK 1586
Query: 4045 DEKEE---------AEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN----- 4182
DE+ + E +++ L+ EI + R A ++K E +N+ +L N
Sbjct: 1587 DEEIDQLKRNHIRVVESMQSTLDAEIRS-RNDAIRIKKKMEGDLNEMEIQLNHSNRMAAE 1645
Query: 4183 -LRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSM-------ELENVRASHRDSEKR 4338
LR+ + Q L+++++ + L+ ++ ++++L E+E +RA+ +E+
Sbjct: 1646 ALRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQTERS 1705
Query: 4339 QKKFESQM--AEERVAV----------QKALLDRDAMS---------QELRDRETRVLSL 4455
+K E ++ A ERV + K L+ D QE R+ E +
Sbjct: 1706 RKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKA 1765
Query: 4456 LNEVDIMKEHLEES-------DRVRRSLQQELQDSISNKDDFG--------KNVHELEKA 4590
+ + +M E L++ +R++++L+Q ++D D+ K + +LE
Sbjct: 1766 ITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEAR 1825
Query: 4591 KRSLEAEL-NDMRVQMEEL-----------EDNLQIAEDAR--LRLEVTNQALKSESDRA 4728
R LE E+ N+ + +E + E Q ED + LRL+ L+S+ +A
Sbjct: 1826 VRELEGEVENEQKRNVEAIKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQSKV-KA 1884
Query: 4729 ISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
+ EAEE+ L + R +++ELE + A S K+ + E+ ++
Sbjct: 1885 YKRQAEEAEEQSNVNLAKFRKIQHELEEAEERADIAESQVNKLRVKSREVHTKI 1938
Score = 70.1 bits (170), Expect = 6e-10
Identities = 91/453 (20%), Positives = 190/453 (41%), Gaps = 36/453 (7%)
Frame = +1
Query: 4492 ESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAE- 4668
E+++ ++++E + + N ELE+ +L E ND+++Q++ D+L AE
Sbjct: 851 ETEKEMANMKEEFEKTKENLAKAEAKRKELEEKMVALMQEKNDLQLQVQSEADSLADAEE 910
Query: 4669 --DARLRLEVTNQA-LKSESDRAISNKDVEAE--EKRRGLLKQIRDLENELENEKRGKSG 4833
D ++ ++ +A +K ++RA +++ AE K+R L + +L+ ++++ + +
Sbjct: 911 RCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAK 970
Query: 4834 AVSHRKKIENQIGELEQQL----EVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKED 5001
+ EN++ L +++ E +L +E + Q E ++ +
Sbjct: 971 VEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKA 1030
Query: 5002 IAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRR 5181
L ++ D +E EQ ++ L +A+++ +K++
Sbjct: 1031 KIKLEQQVD----DLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMD----VENDKQQ 1082
Query: 5182 LEAKIAQXXXXXXXXQSNCE----LAIDKQRK---AQVQLEQITTDLSMERTLNQKTEAE 5340
L+ K+ + QS E L + Q+K Q ++E++ ++ ER K E +
Sbjct: 1083 LDEKLKKKEFEMSNLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQ 1142
Query: 5341 KQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRA-AR 5517
+ L R + ++ E GA S EA+ Q + L +E T + A A
Sbjct: 1143 RSDLSRELEEISERLEE-AGGATSAQIEMNKKREAEFQKMRRDL----EEATLQHEATAA 1197
Query: 5518 RLEKRLNDTTQQFEDEKRANEQAKELLEK-------------SNLK-----NRNLRRQLD 5643
L K+ D+ + ++ ++ K+ LEK SN++ NL +
Sbjct: 1198 TLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMEVISKSKGNLEKMCR 1257
Query: 5644 EAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
ED++S +TK QR ++L +L E
Sbjct: 1258 TLEDQVSELKTKEEEQQRLINELTAQRGRLQTE 1290
>gi|24584714|ref|NP_724009.1| CG17927-PL [Drosophila melanogaster]
gi|22946670|gb|AAN10969.1| CG17927-PL [Drosophila melanogaster]
Length = 1936
Score = 1114 bits (2882), Expect = 0.0
Identities = 677/1916 (35%), Positives = 1072/1916 (55%), Gaps = 31/1916 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K CW+PD+ EG+L+G IK D V V L + + +D +Q+ NPPK++K EDMS
Sbjct: 35 KKSCWIPDEKEGYLLGEIKATKGDIVSVGLQGGETR-DLKKDLLQQVNPPKYEKAEDMSN 93
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LTYLN+ASVLHNL+ RYY+ LIYTYSGLFCV INPYK+ P+Y+ + ++GK+R+E+PP
Sbjct: 94 LTYLNDASVLHNLRQRYYNKLIYTYSGLFCVAINPYKRYPVYTNRCAKMYRGKRRNEVPP 153
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIFAI+D AY ML +QS+L TGESGAGKTENTKKVI Y A V +K + AA+
Sbjct: 154 HIFAISDGAYVDMLTNHVNQSMLITGESGAGKTENTKKVIAYFATVGA---SKKTDEAAK 210
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
G LE Q++Q NP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++G
Sbjct: 211 SK-----------GSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFGPTGKLAG 259
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSE-YLLEGVDNYRFLVNRGITL 972
A+IE YLLEK+RV+ Q ERS+HIFYQI+ G K +L + + +Y + +T+
Sbjct: 260 ADIETYLLEKARVISQQSLERSYHIFYQIMSGSVPGVKEMCFLSDNIYDYYNVSQGKVTV 319
Query: 973 PNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRV 1152
PN+DD +EF + I+GF E + R+ +AV+ +G ++F Q + +QA +
Sbjct: 320 PNMDDGEEFQLADQAFDILGFTKQEKEDVYRITAAVMHMGGMKFKQRGREEQAEQDGEEE 379
Query: 1153 IQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLV 1332
+V L G EL K L+PRIKVG EFV + +N +Q ++ A+ K ++RLFKWLV
Sbjct: 380 GGRVSKLFGCDTAELYKNLLKPRIKVGNEFVTQGRNVQQVTNSIGALCKGVFDRLFKWLV 439
Query: 1333 TRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQE 1512
+ N++LD T ++ FIG+LDIAGFEIF+ N FEQ+CIN+TNEKLQQ FN+ MF++EQE
Sbjct: 440 KKCNETLD-TQQKRQHFIGVLDIAGFEIFEYNGFEQLCINFTNEKLQQFFNHIMFVMEQE 498
Query: 1513 EYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NK 1689
EY++EGI WDFIDFG+DL IDLIEKPMG+L++L+EE +FPKA D++F EKL TH K
Sbjct: 499 EYKKEGINWDFIDFGMDLLACIDLIEKPMGILSILEEESMFPKATDQTFSEKLTNTHLGK 558
Query: 1690 HPKFIVPDM----RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVA 1857
F P + +HFA+ HYAG V Y+ WL KN DPLN+ VV + S + +
Sbjct: 559 SAPFQKPKPPKPGQQAAHFAIAHYAGCVSYNITGWLEKNKDPLNDTVVDQFKKSQNKLLI 618
Query: 1858 GIWKDAEFAGICAAEMNETAFGMRSRK-GMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCI 2034
I+ A+ AG E A G R +K G F TVS +KEQL LMTTLR+T PHFVRCI
Sbjct: 619 EIF--ADHAGQSGG--GEQAKGGRGKKGGGFATVSSAYKEQLNSLMTTLRSTQPHFVRCI 674
Query: 2035 IPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKN 2214
IPN K+ G ++++LV+ QL CNGVLEGIRICR+GFPNR+ + +F+ RY+IL P I
Sbjct: 675 IPNEMKQPGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKMRYQILNPAGI-VG 733
Query: 2215 FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRG 2394
D K+ ++ + +D ++YRIG +KVFFR GVL +EE RD +L ++ QA RG
Sbjct: 734 VDDPKKCGSIILESTALDPDMYRIGHTKVFFRAGVLGQMEEFRDERLGKIMSWMQAWARG 793
Query: 2395 FLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDD 2574
+LSR+ + N YL+LR W W++L+ KVKPLL V+R +DEI A+ +
Sbjct: 794 YLSRKGFKKLQEQRVALKVVQRNLRKYLQLRTWPWYKLWQKVKPLLNVSRIEDEI-ARLE 852
Query: 2575 ELRATKERLLKMEHDFRENEKKLD-QVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQ 2751
E E L E R+ + L+ +++ E+ + + L E + + +L +
Sbjct: 853 EKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQDYQERNAKLTAQKN 912
Query: 2752 ELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQ 2931
+LE + D+++RL+ ++K + + DK D
Sbjct: 913 DLENQLRDIQERLTQEEDARNQLFQQKKKADQEISGLKKDIEDLELNVQKAEQDKATKDH 972
Query: 2932 XXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHE 3111
+ + +L E++ H K K +LE L E
Sbjct: 973 QIRNLNDEIAHQDELINKLNKEKKMQGETNQKTGEELQAAEDKINHLNKVKAKLEQTLDE 1032
Query: 3112 LEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTR 3291
LE L RE++ + ++E+ KRK+ +L+ +++ +A+ +EL + ++D+EL +
Sbjct: 1033 LEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVADLERNKKELEQTIQRKDKELSSITAK 1092
Query: 3292 YDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDK 3471
++E V Q+Q++++Q I+EL E++E ER AR KAE R ++ +LE++ G+ L++
Sbjct: 1093 LEDEQVVVLKHQRQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEEL-GERLEE 1151
Query: 3472 VDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKK 3648
AT Q +L +++ E++ +R +E+ E + + K + V E+ +Q++Q K
Sbjct: 1152 AGGATSAQIELNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNK 1211
Query: 3649 QRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRT 3828
+++ E + E L +A +K K + L E+Q+ L DE RT
Sbjct: 1212 LKAKAEHDRQTCHNELNQTRTACDQLGRDKAAQEKIAKQLQHTLNEVQSKL---DETNRT 1268
Query: 3829 LIDQLERSRDEL----DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIA 3996
L D + S+ +L L R EE E + + + + +R +
Sbjct: 1269 LND-FDASKKKLSIENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERAT 1327
Query: 3997 NINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHAARQGAGEARRKAEE---SVNQQLE 4164
+ + R LE + + L ++ +EEAEG +A L++++ A A R K E + +++LE
Sbjct: 1328 LLGKFRNLEHDLDNLREQVEEEAEG-KADLQRQLSKANAEAQVWRSKYESDGVARSEELE 1386
Query: 4165 ELRKKNLRDVEHLQKQLEESEVAKERILQ-------SKKKIQQELEDSSMELENVRASHR 4323
E ++K LQ +L E+E E + Q +K+++ E+ED +E++ A
Sbjct: 1387 EAKRK-------LQARLAEAEETIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIAN 1439
Query: 4324 DSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDR 4503
+EK+QK F+ + E ++ V + DA +E R+ T + L + +E LE R
Sbjct: 1440 AAEKKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRR 1499
Query: 4504 VRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLR 4683
++L E++D + + G+N+HE+EKA++ LEAE ++++ +EE E L+ E+ LR
Sbjct: 1500 ENKNLADEVKDLLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLR 1559
Query: 4684 LEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIEN 4863
++ ++ E DR I K+ E E R+ + + ++ LE E +GK+ A+ +KK+E
Sbjct: 1560 AQLELSQVRQEIDRRIQEKEEEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEA 1619
Query: 4864 QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRA 5043
I ELE L+ AN+ E + Q EE ++A++D L ++R+ A
Sbjct: 1620 DINELEIALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANA 1679
Query: 5044 VEAEREQ----LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXX 5211
++ E E+ L +A+ G QA ++ A+ IS+ KR+LE+++
Sbjct: 1680 LQNELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISA-AKRKLESELQTLHS 1738
Query: 5212 XXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITE 5391
+ + + +K +KA V ++ +L E+ Q E +++LE+ ++ + ++ E
Sbjct: 1739 DLDELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDE 1798
Query: 5392 LESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKR 5571
E+ A + + LE +V+ LE++L+ E + A + R+ E+R+ + + Q E++++
Sbjct: 1799 AEANALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRK 1858
Query: 5572 ANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQR---EADDLLDANEQ 5730
+E+ ++L++K K + +RQ++EAE+ + K R Q+ EA++ D EQ
Sbjct: 1859 NHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQ 1914
Score = 151 bits (382), Expect = 2e-34
Identities = 178/950 (18%), Positives = 386/950 (39%), Gaps = 62/950 (6%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDE 3267
RLE + + E+ E + + ELE KLLAE D L+ + G +++
Sbjct: 850 RLEEKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQD---------- 899
Query: 3268 ELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEK 3447
Y E +A +T Q D++ + +++E + E +ARN+ +++ ++
Sbjct: 900 --------YQERNAKLTA---QKNDLENQLRDIQERLTQEEDARNQLFQQKKKADQEISG 948
Query: 3448 VKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+K D+ D + + KD ++ I Q + K+ ++K ++ +
Sbjct: 949 LKKDIEDLELNVQKAEQDKATKDHQIRNLNDEIAH-QDELINKLNKEKKMQGETNQKTGE 1007
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAE 3807
+++ + + + L K + + +Q ++ + + R D++K ++ E L Q +A+
Sbjct: 1008 ELQAAEDKINHLNKVKAKLEQTLDELEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVAD 1067
Query: 3808 SDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL 3987
+ +K+ L ++R EL + E+E+ QR++
Sbjct: 1068 LERNKKELEQTIQRKDKELSSITAKLEDEQVVVLKHQRQIKELQA--------------- 1112
Query: 3988 KIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEE 4167
R +LE+E A + +AE RA L +E+ + GE +A + + Q+E
Sbjct: 1113 ------RIEELEEEVEAERQARAKAEKQRADLAREL----EELGERLEEAGGATSAQIE- 1161
Query: 4168 LRKKNLRDVEHLQKQLEESEVAKERILQS-KKKIQQELEDSSMELENVRASHRDSEKRQK 4344
L KK ++ L++ LEE+ + E L + +KK + + + +++ + +E ++
Sbjct: 1162 LNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNKLKAKAEHDRQ 1221
Query: 4345 KFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQ 4524
+++ + R A + D+ A + + + + + +++D L + D ++ L
Sbjct: 1222 TCHNELNQTRTACDQLGRDKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSI 1281
Query: 4525 ELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE--------------LE---DN 4653
E D + ++ V +L K K SL +L D + +E LE DN
Sbjct: 1282 ENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERATLLGKFRNLEHDLDN 1341
Query: 4654 L--QIAEDARLRLEVTNQALKSESDRAISNKDVEA---------EEKRRGLLKQIRDLEN 4800
L Q+ E+A + ++ Q K+ ++ + E+ EE +R L ++ + E
Sbjct: 1342 LREQVEEEAEGKADLQRQLSKANAEAQVWRSKYESDGVARSEELEEAKRKLQARLAEAEE 1401
Query: 4801 ELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEE 4980
+E+ + G ++++ ++ +L+ +++ AN + E++++ ++
Sbjct: 1402 TIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIANAAEKKQKAFDKIIGEWKLKVDD 1461
Query: 4981 ARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGG-G 5157
+ R + ++ E+ +E E + + K +GG
Sbjct: 1462 LAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGRN 1521
Query: 5158 ISSEEK--RRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKT 5331
I EK +RLEA+ + ++ E +K +AQ++L Q+ ++ +R + +K
Sbjct: 1522 IHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEI--DRRIQEKE 1579
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRARA--QMAALEAKVQYLEDQLNVEGQEKTAAN 5505
E + + + R + LE+ A+ +A A LEA + LE L+ + A
Sbjct: 1580 EEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQ 1639
Query: 5506 RAARRLEKRLNDTTQQFEDEKR----------------------------ANEQAKELLE 5601
+ +R +++L D E+E+R EQA
Sbjct: 1640 KNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRR 1699
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
++ + + QL+E + + R ++ E L ++L E N
Sbjct: 1700 QAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDELLNEAKN 1749
Score = 82.4 bits (202), Expect = 1e-13
Identities = 82/418 (19%), Positives = 183/418 (43%), Gaps = 25/418 (5%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L +Q+ E ++++ + + LE K +L A LE+++ L ++ KV +L + +E
Sbjct: 1511 LLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQE 1570
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ ++ +EE N ++ Q +D ++ +E E + +A ++++ A + ++
Sbjct: 1571 IDRRIQEKEEEFENTR------KNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINEL 1624
Query: 3451 KGDVLDKVDEATM-LQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+ LD ++A Q + R +++ + A+E+ Q + EQ R+ L +
Sbjct: 1625 E-IALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDA-REQLGISERRANALQN 1682
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL-- 3801
++E+ + Q ++ + QA+QE AD +++ + A A I ++ E+ L + ++L
Sbjct: 1683 ELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDE 1742
Query: 3802 ----AESDEHKRT--------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
A++ E K L D+L +D ++R+ E +Q RL A
Sbjct: 1743 LLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAEAN 1802
Query: 3946 XXXXXXXXXXXTRLKIANIN------RARQLEDEKNALLDEKEEAE-GLRAHLEKEIHAA 4104
++ + + R + +KN E+ E ++ +++ H
Sbjct: 1803 ALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRKNHER 1862
Query: 4105 RQGAGEARRKAEESVNQQLEELRK---KNLRDVEHLQKQLEESEVAKERILQSKKKIQ 4269
Q + ++ ++ +Q+EE + NL Q++LEE+E + Q+ K +
Sbjct: 1863 MQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQAISKFR 1920
>gi|12003423|gb|AAG43570.1| skeletal muscle myosin heavy chain
MyHC-EO/IIL [Oryctolagus cuniculus]
gi|12003425|gb|AAG43571.1| skeletal muscle myosin heavy chain
MyHC-EO/IIL [Oryctolagus cuniculus]
gi|12003427|gb|AAG43572.1| skeletal muscle myosin heavy chain
MyHC-EO/IIL [Oryctolagus cuniculus]
Length = 1938
Score = 1114 bits (2882), Expect = 0.0
Identities = 646/1892 (34%), Positives = 1054/1892 (55%), Gaps = 14/1892 (0%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K C+ D E ++ G I+ ND+V V+ +D R +T++ D V NPPKFDKIEDM+
Sbjct: 35 KKACFAVDDKEMYVKGMIQSRENDKVTVKTLD-DRTLTLNSDQVFPMNPPKFDKIEDMAM 93
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
+T+L+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PP
Sbjct: 94 MTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPP 153
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIF+I+D AY+ ML +R++QSIL TGESGAGKT NTK+VIQY A +A K +
Sbjct: 154 HIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKEQQPGK 213
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
G LE Q++QANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++
Sbjct: 214 MQ-----------GTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLAS 262
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRF-LVNRG-IT 969
A+IE YLLEKSRV Q ERS+HIFYQI+ E + LL + + F V++G +T
Sbjct: 263 ADIETYLLEKSRVTFQLSSERSYHIFYQIMSN-KKPELIDLLLISTNPFDFPFVSQGEVT 321
Query: 970 LPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDR 1149
+ ++DD +E +T N++ I+GF+ +E I ++ AV+ GN++F Q+++ +QA
Sbjct: 322 VASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMHYGNMKFKQKQREEQAEPDGTE 381
Query: 1150 VIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWL 1329
V K +L+GL E+ K PR+KVG E+V K QN +Q +V A+AKA YE++F W+
Sbjct: 382 VADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGALAKAVYEKMFLWM 441
Query: 1330 VTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQ 1509
VTRIN+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQ
Sbjct: 442 VTRINQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQ 500
Query: 1510 EEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-N 1686
EEY++EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H
Sbjct: 501 EEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLG 560
Query: 1687 KHPKFIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVA 1857
K F P ++++HF++VHYAG VDY+ WL KN DPLNE VVGL Q S ++
Sbjct: 561 KSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSALKLLS 620
Query: 1858 GIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCII 2037
++ + +AG A + + G + + F+TVS + +E L KLMT LR+T PHFVRC+I
Sbjct: 621 FLF--SNYAGAEAGDSGGSKKGGKKKGSSFQTVSAVFRENLNKLMTNLRSTHPHFVRCLI 678
Query: 2038 PNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-N 2214
PN K G ++ LV+ QLRCNGVLEGIRICR+GFP+R+ + +F+ RY IL IP+
Sbjct: 679 PNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIPEGQ 738
Query: 2215 FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRG 2394
FID K + K++ ++D+D YR G +KVFF+ G+L LEE RD KL L+ QA CRG
Sbjct: 739 FIDSKNASEKLLNSIDVDREQYRFGHTKVFFKAGLLGLLEEMRDEKLVTLMTRTQALCRG 798
Query: 2395 FLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDD 2574
+L R + N A++ +++W W LF K+KPLL+ + E+ +
Sbjct: 799 YLMRVEFKKMMERRDSIFCIQYNIRAFMNVKHWPWMNLFFKIKPLLKSAEAEKEMATMKE 858
Query: 2575 ELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQE 2754
+ KE L + E +E E+K+ ++ E+ +Q Q+Q E+EN + ++ L +
Sbjct: 859 DFERAKEELARSEARRKELEEKMVTLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKIQ 918
Query: 2755 LEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQX 2934
LE V ++ +RL +R + +K +
Sbjct: 919 LEAKVKELNERLEEEEEMNSDLVAKKRTLEDKCCSLKRDIDDLELTLTKVEKEKHATENK 978
Query: 2935 XXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHEL 3114
++ L E++ +K +LE Q +L
Sbjct: 979 VKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDL 1038
Query: 3115 EQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRY 3294
E L +E++ +++LE+ KRKL +L+ +++ + + +++ +L K++ E+ T+
Sbjct: 1039 EGSLEQEKKLRADLERVKRKLEGDLKMAQESIMDLENDKQQVEEKLKKKEFEISQLQTKI 1098
Query: 3295 DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKV 3474
D+E +QK+++++Q +EL E++E E R K E R ++ +LE++ + L++
Sbjct: 1099 DDEQVQSLQLQKKIKELQARTEELEEEIEAEHTLRAKIEKQRSDLARELEEI-SERLEEA 1157
Query: 3475 DEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQ 3651
AT Q M++K E E +R +E+ E + K + V EL +QI+ ++
Sbjct: 1158 SGATSAQIEMNKKREAEFQKLRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRV 1217
Query: 3652 RSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTL 3831
+ +LEK++++ E D+A I + S++++++ + E EI+A + + L
Sbjct: 1218 KQKLEKEKSELKMEIDDLASNIETVSKSKSNVERMCRSVEDQFNEIKAKDDQQTQLIHDL 1277
Query: 3832 IDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRA 4011
Q R + + LN EE+E + + + T+ K A +
Sbjct: 1278 NMQKARLQTQNGELNHQVEEKESLISQLTKGKQALSQQLEEVKRQLEEETKAKNALAHAL 1337
Query: 4012 RQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRD 4191
+ + + L ++ EE + +A L++ + A + R K E Q+ EEL + +
Sbjct: 1338 QSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 1397
Query: 4192 VEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQM 4362
+ LQ+ E +E A + + ++K+++Q E++D ++LE + +K+Q+ F+ +
Sbjct: 1398 AQRLQEAEENTETANSKCASLEKTKQRLQGEVDDLMLDLERANTACGTLDKKQRNFDKVL 1457
Query: 4363 AEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSI 4542
AE + + ++ + +A +E R T + + N + + E LE R ++LQ+E+ D
Sbjct: 1458 AEWKQKLDESQAELEAAQKESRALSTEIFKMRNAYEEVVEQLETLRRENKNLQEEIADLT 1517
Query: 4543 SNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESD 4722
+ GKN+ E+EK K+ +E E +D++ +EE E +L+ E LR+++ +KSE D
Sbjct: 1518 EQMAETGKNLQEVEKTKKQVEQEKSDLQAALEEAEGSLEHEESKILRVQLELNQVKSELD 1577
Query: 4723 RAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVAN 4902
R ++ KD E E+ +R + L++ L+ E R ++ A+ +KK+E + E+E QL A+
Sbjct: 1578 RKLTEKDEEMEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHAS 1637
Query: 4903 RLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANE 5082
R E + Q+ ++A ++ ED+ L +R+ ++ E E+++ A E
Sbjct: 1638 RQVAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAMVERRNGLLQEELEEMKVALE 1697
Query: 5083 GLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAID 5253
+ R+ Q KR+LEA +AQ A +
Sbjct: 1698 QTERTRRLSEQELLDASDRVQLLHSQNTSLINTKRKLEADLAQCQAEVENSLQESRNAEE 1757
Query: 5254 KQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMA 5433
K +KA + +L E+ + E K++LE++ +D + ++ E E A + Q+
Sbjct: 1758 KAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQ 1817
Query: 5434 ALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNL 5613
LE +V+ LE +L+ E + A + A + E+++ + T Q E++++ + ++L++K
Sbjct: 1818 KLENRVRELETELDAEQKRGAEALKGAHKYERKVKEMTYQAEEDRKNFLRLQDLVDKLQA 1877
Query: 5614 KNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
K ++ +RQ +EAE++ + + ++ R VQ E ++
Sbjct: 1878 KVKSYKRQAEEAEEQANTQLSRCRRVQHELEE 1909
Score = 130 bits (327), Expect = 4e-28
Identities = 176/869 (20%), Positives = 360/869 (41%), Gaps = 75/869 (8%)
Frame = +1
Query: 2476 LKLRNWQWWRLFTKVKP----LLQVTRTDDEIRAKDDELRATKERLLKMEHDFREN-EKK 2640
LK + ++ +L TK+ LQ+ + E++A+ +EL E ++ EH R EK+
Sbjct: 1084 LKKKEFEISQLQTKIDDEQVQSLQLQKKIKELQARTEEL----EEEIEAEHTLRAKIEKQ 1139
Query: 2641 LDQVIVERAVIQEQLQQES-----------ENSAELDDIRGRLQTRNQELEYIVNDMR-- 2781
+ E I E+L++ S + AE +R L+ + E +R
Sbjct: 1140 RSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKLRRDLEEATLQHEATAATLRKK 1199
Query: 2782 --DRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXX 2955
D ++ ++K + + K+NV++
Sbjct: 1200 HADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNIETVSKSKSNVERMCRSVEDQ 1259
Query: 2956 XXXXQDAYDXXXXXXXXXXXXXXGLTTQL--LDHEERAKHGV-----KAKGRLENQLHEL 3114
+ D L TQ L+H+ K + K K L QL E+
Sbjct: 1260 FNEIKAKDDQQTQLIHDLNMQKARLQTQNGELNHQVEEKESLISQLTKGKQALSQQLEEV 1319
Query: 3115 EQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRY 3294
++ L E + K+ L + + + ++ E+ EL L K + E+ T+Y
Sbjct: 1320 KRQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKY 1379
Query: 3295 DEESANVTL-MQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDK 3471
+ ++ T +++ + + + E E+ ET + E T++ + +++ + D L++
Sbjct: 1380 ETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVDDLMLD-LER 1438
Query: 3472 VDEATMLQDLMSRKDEEVNAT-KRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKK 3648
+ A D R ++V A K+ +++ Q +E +E +A S ++ ++ + E+ +
Sbjct: 1439 ANTACGTLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRA-LSTEIFKMRNAYEEVVE 1497
Query: 3649 QRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESD---EH 3819
Q L ++ +E AD+ +++A + +++K +K E ++QA L E++ EH
Sbjct: 1498 QLETLRRENKNLQEEIADLTEQMAETGKNLQEVEKTKKQVEQEKSDLQAALEEAEGSLEH 1557
Query: 3820 KRTLID----QLERSRDELDH-LNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTR 3984
+ + I +L + + ELD L EE E N QR R
Sbjct: 1558 EESKILRVQLELNQVKSELDRKLTEKDEEMEQLKRNSQRAAEALQSVLDAEIRSRNDALR 1617
Query: 3985 LKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESV--NQQ 4158
LK +++E + N + + A A +K + + +++ ++++ N+
Sbjct: 1618 LK-------KKMEGDLNEMEIQLGHASRQVAETQKHLRTVQGQLKDSQLHLDDALRSNED 1670
Query: 4159 LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKR 4338
L+E R LQ++LEE +VA E+ ++++ +QEL D+S ++ + + +
Sbjct: 1671 LKEQLAMVERRNGLLQEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINT 1730
Query: 4339 QKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEES------- 4497
++K E+ +A+ + V+ +L QE R+ E + + + +M E L++
Sbjct: 1731 KRKLEADLAQCQAEVENSL-------QESRNAEEKAKKAITDAAMMAEELKKEQDTSAHL 1783
Query: 4498 DRVRRSLQQELQDSISNKDDFG--------KNVHELEKAKRSLEAELN------------ 4617
+R++++L+Q ++D D+ K + +LE R LE EL+
Sbjct: 1784 ERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELETELDAEQKRGAEALKG 1843
Query: 4618 ---------DMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRG 4770
+M Q EE N +D +L+ ++ K +++ EAEE+
Sbjct: 1844 AHKYERKVKEMTYQAEEDRKNFLRLQDLVDKLQAKVKSYKRQAE--------EAEEQANT 1895
Query: 4771 LLKQIRDLENELENEKRGKSGAVSHRKKI 4857
L + R +++ELE + A S K+
Sbjct: 1896 QLSRCRRVQHELEEAEERADIAESQVNKL 1924
Score = 122 bits (307), Expect = 8e-26
Identities = 145/765 (18%), Positives = 317/765 (40%), Gaps = 43/765 (5%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A E +++ + + +R +LE++ QE+ D+ ++ + D ++
Sbjct: 850 EKEMATMKEDFERAKEELARSEARRKELEEKMVTLLQEKNDLQLQVQSETENLMDAEERC 909
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ L E +E L+ + D+ L R ++ E ++
Sbjct: 910 EGLIKSKIQLEAKVKELNERLEEEEEMNSDLVAKKRTLEDKCCSLKRDIDDLELTLTKVE 969
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ K A N+ + L +E AL EE +K +
Sbjct: 970 KE---------------------KHATENKVKNLSEEMTAL----EENISKLTKEKKSLQ 1004
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
A Q + + E+ VN L ++ K + + L+ LE+ + + + + K+K++ +L
Sbjct: 1005 EAHQQTLDDLQVEEDKVNG-LIKINAKLEQQTDDLEGSLEQEKKLRADLERVKRKLEGDL 1063
Query: 4279 ---EDSSMELENVRASHRDSEKRQKKFESQMAEERV--------AVQKALLDRDAMSQEL 4425
++S M+LEN + + K+ K+FE + ++ +QK + + A ++EL
Sbjct: 1064 KMAQESIMDLENDKQQVEEKLKK-KEFEISQLQTKIDDEQVQSLQLQKKIKELQARTEEL 1122
Query: 4426 RDR-----------ETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNV 4572
+ E + L E++ + E LEE+ + +++ + + +F K
Sbjct: 1123 EEEIEAEHTLRAKIEKQRSDLARELEEISERLEEAS---GATSAQIEMNKKREAEFQKLR 1179
Query: 4573 HELEKAKRSLEAELNDMRVQ----MEELEDNLQIAEDARLRLEVTNQALKSESDRAISNK 4740
+LE+A EA +R + + EL + + + + +LE LK E D SN
Sbjct: 1180 RDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNI 1239
Query: 4741 DVEAEEKR--RGLLKQIRDLENELENEKRGKSGAV----SHRKKIENQIGELEQQLEVAN 4902
+ ++ K + + + D NE++ + ++ + + +++ Q GEL Q+E
Sbjct: 1240 ETVSKSKSNVERMCRSVEDQFNEIKAKDDQQTQLIHDLNMQKARLQTQNGELNHQVEEKE 1299
Query: 4903 RLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLR----EADRKFRAVEAEREQLR 5070
L + E + + EE +AK +A L+ + D E E+E
Sbjct: 1300 SLISQLTKGKQALSQQLEEVKRQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEAKA 1359
Query: 5071 EANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAI 5250
E L +A + + E K++L ++ + S C
Sbjct: 1360 ELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLE 1419
Query: 5251 DKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQM 5430
+++ Q +++ + DL T + ++++ ++ ++K K+ E ++ ++ A+ +
Sbjct: 1420 KTKQRLQGEVDDLMLDLERANTACGTLDKKQRNFDKVLAEWKQKLDESQAELEA-AQKES 1478
Query: 5431 AALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSN 5610
AL ++ + + ++ R + L++ + D T+Q + + ++ ++ ++
Sbjct: 1479 RALSTEIFKMRNAYEEVVEQLETLRRENKNLQEEIADLTEQMAETGKNLQEVEKTKKQVE 1538
Query: 5611 LKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
+ +L+ L+EAE + E +K VQ E L +L R+L
Sbjct: 1539 QEKSDLQAALEEAEGSLEHEESKILRVQLE---LNQVKSELDRKL 1580
Score = 45.1 bits (105), Expect = 0.021
Identities = 69/376 (18%), Positives = 133/376 (35%), Gaps = 51/376 (13%)
Frame = +1
Query: 4759 KRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXX 4938
K + LLK + E E+ K A + E + ELE+++ + K +
Sbjct: 839 KIKPLLKSA-EAEKEMATMKEDFERAKEELARSEARRKELEEKMVTLLQEKNDLQLQVQS 897
Query: 4939 XXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQL----REANEGLMQARKQ 5106
+ + CE ++K + A ++E + + E L R + ++
Sbjct: 898 ETENLMDAEERCEGLIKSKIQLEAKVKELNERLEEEEEMNSDLVAKKRTLEDKCCSLKRD 957
Query: 5107 XXXXXXXXXXXRAKGGGIS------SEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQR-- 5262
+ SEE LE I++ Q + +D +
Sbjct: 958 IDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVE 1017
Query: 5263 --------KAQVQLEQITTD----LSMERTLNQKTEAEKQSLERSNRDYKAKITELESGA 5406
K +LEQ T D L E+ L E K+ LE + + I +LE+
Sbjct: 1018 EDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERVKRKLEGDLKMAQESIMDLENDK 1077
Query: 5407 QS---------------------------RARAQMAALEAKVQYLEDQLNVEGQEKTAAN 5505
Q + + ++ L+A+ + LE+++ E +
Sbjct: 1078 QQVEEKLKKKEFEISQLQTKIDDEQVQSLQLQKKIKELQARTEELEEEIEAEHTLRAKIE 1137
Query: 5506 RAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHR 5685
+ L + L + +++ E+ A E+ +K + + LRR L+EA + E T
Sbjct: 1138 KQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKLRRDLEEA--TLQHEATAAT 1195
Query: 5686 NVQREADDLLDANEQL 5733
++ AD + + EQ+
Sbjct: 1196 LRKKHADSVAELGEQI 1211
>gi|7669506|ref|NP_005954.2| myosin, heavy polypeptide 1, skeletal
muscle, adult; myosin heavy chain IIx/d [Homo sapiens]
gi|13638390|sp|P12882|MYH1_HUMAN Myosin heavy chain, skeletal muscle,
adult 1 (Myosin heavy chain IIx/d) (MyHC-IIx/d)
gi|4808815|gb|AAD29951.1| myosin heavy chain IIx/d [Homo sapiens]
Length = 1939
Score = 1114 bits (2882), Expect = 0.0
Identities = 652/1890 (34%), Positives = 1052/1890 (55%), Gaps = 16/1890 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V D E F+ +++ +V + + VT+ D V NPPK+DKIEDM+ +T+L
Sbjct: 39 FVVDPKESFVKATVQSREGGKVTAK-TEAGATVTVKDDQVFPMNPPKYDKIEDMAMMTHL 97
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 98 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFS 157
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVA--GATRNKSLNAAAQQN 621
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A G + + + + Q
Sbjct: 158 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQ- 216
Query: 622 IVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGAN 801
G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+
Sbjct: 217 -----------GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASAD 265
Query: 802 IEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLP 975
IE YLLEKSRV Q + ERS+HIFYQI+ + E LL + +Y F+ IT+P
Sbjct: 266 IETYLLEKSRVTFQLKAERSYHIFYQIMSN-KKPDLIEMLLITTNPYDYAFVSQGEITVP 324
Query: 976 NVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVI 1155
++DD +E +T +++ I+GF DE SI ++ AV+ GN++F Q+++ +QA V
Sbjct: 325 SIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVA 384
Query: 1156 QKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVT 1335
K +L L +L KA PR+KVG E+V K Q +Q AV A+AKA Y+++F W+VT
Sbjct: 385 DKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYDKMFLWMVT 444
Query: 1336 RINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEE 1515
RIN+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEE
Sbjct: 445 RINQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEE 503
Query: 1516 YQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKH 1692
Y++EGIEW FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL + H K
Sbjct: 504 YKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKS 563
Query: 1693 PKFIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGI 1863
F P + ++HF+++HYAG VDY+ WL KN DPLNE VVGL Q S +A +
Sbjct: 564 NNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLALL 623
Query: 1864 WKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPN 2043
+ A A AE G + + F+TVS L +E L KLMT LR+T PHFVRCIIPN
Sbjct: 624 FVGATGA---EAEAGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPN 680
Query: 2044 HEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFI 2220
K G + LVL QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L IP+ FI
Sbjct: 681 ETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFI 740
Query: 2221 DGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFL 2400
D K++ K++ ++DID Y+ G +KVFF+ G+L LEE RD KL LI QA CRGFL
Sbjct: 741 DSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQAMCRGFL 800
Query: 2401 SRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDEL 2580
+R Y N A++ +++W W +L+ K+KPLL+ T+ E+ +E
Sbjct: 801 ARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEF 860
Query: 2581 RATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELE 2760
TKE L K E +E E+K+ ++ E+ +Q Q+Q E+++ A+ ++ +L +LE
Sbjct: 861 EKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLE 920
Query: 2761 YIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXX 2940
+ ++ +R +RK + + +K +
Sbjct: 921 AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 980
Query: 2941 XXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQ 3120
+ L E++ KAK +LE Q+ +LE
Sbjct: 981 NLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEG 1040
Query: 3121 DLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDE 3300
L +E++ + +LE+ KRKL +L+ +++ + ++L+ +L K++ E+ ++ ++
Sbjct: 1041 SLEQEKKIRMDLERAKRKLEGDLKLAQESAMDIENDKQQLDEKLKKKEFEMSGLQSKIED 1100
Query: 3301 ESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDE 3480
E A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L++
Sbjct: 1101 EQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEI-SERLEEAGG 1159
Query: 3481 ATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRS 3657
AT Q M++K E E +R +E+ E + K + V EL +QI+ ++ +
Sbjct: 1160 ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQ 1219
Query: 3658 QLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLID 3837
+LEK++++ E D+A + + ++ +++K + E L EI+ E L
Sbjct: 1220 KLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTA 1279
Query: 3838 QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQ 4017
Q R + E +R +E++ + + R + K A + +
Sbjct: 1280 QRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQS 1339
Query: 4018 LEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVE 4197
+ + L ++ EE + +A L++ + A + R K E Q+ EEL + + +
Sbjct: 1340 SRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQ 1399
Query: 4198 HLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAE 4368
LQ E E + + ++K+++Q E+ED +++E A+ +K+Q+ F+ +AE
Sbjct: 1400 RLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAE 1459
Query: 4369 ERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISN 4548
+ ++ + +A +E R T + + N + + LE R ++LQQE+ D
Sbjct: 1460 WKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQ 1519
Query: 4549 KDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRA 4728
+ GK +HELEK K+ +E E ++++ +EE E +L+ E LR+++ +KSE DR
Sbjct: 1520 IAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRK 1579
Query: 4729 ISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRL 4908
I+ KD E ++ +R ++ + +++ L+ E R ++ A+ +KK+E + E+E QL ANR+
Sbjct: 1580 IAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRM 1639
Query: 4909 KEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGL 5088
E + Q+ ++A +++ED+ L +R+ ++AE E+LR E
Sbjct: 1640 AAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQT 1699
Query: 5089 MQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQ 5259
++RK Q K++LE I+Q A +K
Sbjct: 1700 ERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKA 1759
Query: 5260 RKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAAL 5439
+KA + +L E+ + E K++LE++ +D + ++ E E A + Q+ L
Sbjct: 1760 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1819
Query: 5440 EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKN 5619
EA+V+ LE ++ E + A + R+ E+++ + T Q E++++ + ++L++K K
Sbjct: 1820 EARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKV 1879
Query: 5620 RNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
++ +RQ +EAE++ + +K R +Q E ++
Sbjct: 1880 KSYKRQAEEAEEQSNVNLSKFRRIQHELEE 1909
Score = 162 bits (409), Expect = 1e-37
Identities = 190/916 (20%), Positives = 379/916 (40%), Gaps = 30/916 (3%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + + +++L + + ELE+ L+ E D + + A+ + EE +
Sbjct: 851 KEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCD 910
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE N L K+ R ++ EL++D++ E
Sbjct: 911 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKDIDD-------LE 962
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E L + +++ +E A + A +Q ++ +
Sbjct: 963 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1022
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIAL-LQASRADID 3750
+ + K K +QV++L +EQ KK R LE+ + + + + +AQE A+ ++ + +D
Sbjct: 1023 TLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGD-LKLAQESAMDIENDKQQLD 1081
Query: 3751 KKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLA 3930
+K K E + +Q+ + E ++ L QL++ EL R+ E EE A R
Sbjct: 1082 EKLKKKEFEMSGLQSKI----EDEQALGMQLQKKIKELQ--ARIEELEEEIEAERASRAK 1135
Query: 3931 TAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQ 4110
RL+ A + Q+E +++K EAE
Sbjct: 1136 AEKQRSDLSRELEEISERLEEAGGATSAQIE------MNKKREAE--------------- 1174
Query: 4111 GAGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELE 4281
+ RR EE+ Q LRKK+ V L +Q++ + K+++ + K +++ E++
Sbjct: 1175 -FQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID 1233
Query: 4282 DSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLN 4461
D + +E V + + EK + E Q++E + + + + D + L
Sbjct: 1234 DLASNMETVSKAKGNLEKMCRALEDQLSEIKT-------KEEEQQRLINDLTAQRARLQT 1286
Query: 4462 EVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE 4641
E L+E D + L + Q ++ + + E KAK +L L R +
Sbjct: 1287 ESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDL 1346
Query: 4642 LEDNLQIAEDARLRL---------EVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDL 4794
L + + ++A+ L EV K E+D AI + E EE ++ L ++++D
Sbjct: 1347 LREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETD-AIQRTE-ELEEAKKKLAQRLQDA 1404
Query: 4795 ENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIEC 4974
E +E + +++++N++ +L +E N E++ +C
Sbjct: 1405 EEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKC 1464
Query: 4975 EEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGG 5154
EE E R + ++ E+ + E L + K A+GG
Sbjct: 1465 EETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGG 1524
Query: 5155 -GISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKT 5331
I EK + + + + ++ L ++ + ++QLE ++R + +K
Sbjct: 1525 KRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKD 1584
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSR--ARAQMAALEAKVQYLEDQLNVEGQEKTAAN 5505
E Q R ++ + L++ +SR A +E + +E QLN + A
Sbjct: 1585 EEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEAL 1644
Query: 5506 RAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHR 5685
R R + L DT +D R+ E KE L + L+ +++E + + +
Sbjct: 1645 RNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRK 1704
Query: 5686 NVQREADDLLDANEQL 5733
++E LLDA+E++
Sbjct: 1705 IAEQE---LLDASERV 1717
Score = 142 bits (359), Expect = 8e-32
Identities = 172/901 (19%), Positives = 376/901 (41%), Gaps = 73/901 (8%)
Frame = +1
Query: 3256 KRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVA 3435
K ++ + + EE A +K++ + T+ + + D++ + A + E
Sbjct: 851 KEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCD 910
Query: 3436 QLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVE 3615
QL K K + K+ E T + +EE+NA ++ +K K +
Sbjct: 911 QLIKTKIQLEAKIKEVTE----RAEDEEEINA--------------ELTAKKRKLEDECS 952
Query: 3616 ELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRK-IHEAHLMEIQ 3792
EL I+ + +++EK+++ + + ++ +E+A L + A + K++K + EAH +
Sbjct: 953 ELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLD 1012
Query: 3793 ANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXX 3972
AE D+ TL + ++D L E+E+ +++R
Sbjct: 1013 DLQAEEDK-VNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGD--------- 1062
Query: 3973 XXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVN 4152
LK+A A +E++K L ++ ++ E + L+ +I + E+++
Sbjct: 1063 ----LKLAQ-ESAMDIENDKQQLDEKLKKKEFEMSGLQSKI------------EDEQALG 1105
Query: 4153 QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSE 4332
QL++ K+ +E L++++E ++ + + + + +ELE+ S LE +
Sbjct: 1106 MQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQI 1165
Query: 4333 KRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNE-VDIMKEHLEESDRVR 4509
+ KK E++ + R +++A L +A + LR + ++ L E +D ++ ++ ++ +
Sbjct: 1166 EMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEK 1225
Query: 4510 RSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLE 4689
++ E+ D SN + K LEK R+LE +L++++ + EE + + R RL+
Sbjct: 1226 SEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQ 1285
Query: 4690 VTNQALKSESDRAISNKDVEAEEKRRG---LLKQIRDLENELENEKRGKSGAVSHRKKIE 4860
+ E R + KD + RG +QI +L+ +LE E + KS +
Sbjct: 1286 TES----GEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSR 1341
Query: 4861 NQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIE--------CEEARQAKEDIAALL 5016
+ L +Q E K E +++ + EE +AK+ +A L
Sbjct: 1342 HDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1401
Query: 5017 READRKFRAVEAE-------REQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEK 5175
++A+ AV A+ +++L+ E LM ++ + I +E K
Sbjct: 1402 QDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWK 1461
Query: 5176 RRLEAKIAQXXXXXXXXQS-NCEL------------AIDKQRKAQVQLEQITTDLSME-- 5310
++ E A+ +S + EL ++ ++ L+Q +DL+ +
Sbjct: 1462 QKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIA 1521
Query: 5311 ---------RTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKV---- 5451
+ ++ E EK L+ + + +A + E E G R + ++ ++++V
Sbjct: 1522 EGGKRIHELEKIKKQVEQEKSELQAALEEAEASL-EHEEGKILRIQLELNQVKSEVDRKI 1580
Query: 5452 ------------------QYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRAN 5577
+ ++ L+ E + + A R +++E LN+ Q R
Sbjct: 1581 AEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA 1640
Query: 5578 EQA-------KELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLT 5736
+A + +L+ + L + R ++ +++++ + +Q E ++L EQ
Sbjct: 1641 AEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTE 1700
Query: 5737 R 5739
R
Sbjct: 1701 R 1701
Score = 116 bits (290), Expect = 8e-24
Identities = 174/890 (19%), Positives = 356/890 (39%), Gaps = 113/890 (12%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ +E + +E+D ++ ++KL + E + +Q +++ E +L LQ
Sbjct: 1057 RKLEGDLKLAQESAMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQ 1116
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + +R S R ++E + + +
Sbjct: 1117 ARIEELEEEIE--AERASRAKAEKQRSDLSR--ELEEISERLEEAGGATSAQIEMNKKRE 1172
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K ++
Sbjct: 1173 AEFQKMRRDLEEATLQHEATAATLRKKHADSVAELG---EQIDNLQRVKQKLEKEKSEMK 1229
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K LE+ R L +L + K E+ + +L Q + E
Sbjct: 1230 MEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESG 1289
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ DE+ V+ + + + I+EL+ +E E A++ + + ++
Sbjct: 1290 EYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLRE 1349
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
++ + LQ MS+ + EV TK + IQ T E +EE K K ++++++ +
Sbjct: 1350 QYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQDAEEH 1407
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME-------I 3789
+E + + LEK + + E D+ ++ A+ A +DKK++ + L E
Sbjct: 1408 VEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEET 1467
Query: 3790 QANLAESDEHKRTLIDQL-------ERSRDELDHLNRVREEEEHAFANMQRRLAT----- 3933
A L S + R+L +L E S D+L+ L R + + +++ ++A
Sbjct: 1468 HAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRI 1527
Query: 3934 ------------------AXXXXXXXXXXXXXXTRLKIA-NINRARQLEDEKNALLDEKE 4056
A L+I +N+ + D K A DE+
Sbjct: 1528 HELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEI 1587
Query: 4057 E---------AEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN------LRD 4191
+ E +++ L+ EI + R A ++K E +N+ +L N LR+
Sbjct: 1588 DQMKRNHIRIVESMQSTLDAEIRS-RNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRN 1646
Query: 4192 VEHLQKQLEESEVAKERILQSKKKIQQELEDSSM-------ELENVRASHRDSEKRQKKF 4350
+ Q L+++++ + L+S++ ++++L E+E +RA+ +E+ +K
Sbjct: 1647 YRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIA 1706
Query: 4351 ESQM--AEERVAV----------QKALLDRDAMS---------QELRDRETRVLSLLNEV 4467
E ++ A ERV + K L+ D QE R+ E + + +
Sbjct: 1707 EQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDA 1766
Query: 4468 DIMKEHLEES-------DRVRRSLQQELQDSISNKDDFG--------KNVHELEKAKRSL 4602
+M E L++ +R++++L+Q ++D D+ K + +LE R L
Sbjct: 1767 AMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVREL 1826
Query: 4603 EAELNDMRVQMEELEDNL------------QIAEDAR--LRLEVTNQALKSESDRAISNK 4740
E E+ + + E L Q ED + LRL+ L+++ ++ +
Sbjct: 1827 EGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKV-KSYKRQ 1885
Query: 4741 DVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
EAEE+ L + R +++ELE + A S K+ + E+ ++
Sbjct: 1886 AEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSREVHTKI 1935
Score = 70.1 bits (170), Expect = 6e-10
Identities = 101/454 (22%), Positives = 193/454 (42%), Gaps = 48/454 (10%)
Frame = +1
Query: 4525 ELQDSISN-KDDFGKNVHELEK--AKR--------SLEAELNDMRVQMEELEDNLQIAE- 4668
E + ++N K++F K EL K AKR +L E ND+++Q++ D+L AE
Sbjct: 848 ETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEE 907
Query: 4669 --DARLRLEVTNQA-LKSESDRAISNKDVEAE--EKRRGLLKQIRDLENELENEKRGKSG 4833
D ++ ++ +A +K ++RA +++ AE K+R L + +L+ ++++ + +
Sbjct: 908 RCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAK 967
Query: 4834 AVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAAL 5013
+ EN++ L +++ +E E + + QA+ED
Sbjct: 968 VEKEKHATENKVKNLTEEMAGL----DETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNT 1023
Query: 5014 LREADRKFRA----VEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSE-EKR 5178
L +A K +E EQ ++ L +A+++ A+ + E +K+
Sbjct: 1024 LTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKL-----AQESAMDIENDKQ 1078
Query: 5179 RLEAKIAQXXXXXXXXQSNCE----LAIDKQRKA---QVQLEQITTDLSMERTLNQKTEA 5337
+L+ K+ + QS E L + Q+K Q ++E++ ++ ER K E
Sbjct: 1079 QLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEK 1138
Query: 5338 EKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRA-A 5514
++ L R + ++ E GA S EA+ Q + L +E T + A A
Sbjct: 1139 QRSDLSRELEEISERLEEA-GGATSAQIEMNKKREAEFQKMRRDL----EEATLQHEATA 1193
Query: 5515 RRLEKRLNDTTQQFEDEKRANEQAKELLEK-------------SNLKN-----RNLRRQL 5640
L K+ D+ + ++ ++ K+ LEK SN++ NL +
Sbjct: 1194 ATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMC 1253
Query: 5641 DEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
ED++S +TK QR +DL +L E
Sbjct: 1254 RALEDQLSEIKTKEEEQQRLINDLTAQRARLQTE 1287
>gi|13431716|sp|Q9UKX2|MYH2_HUMAN Myosin heavy chain, skeletal muscle,
adult 2 (Myosin heavy chain IIa) (MyHC-IIa)
gi|4808813|gb|AAD29950.1| myosin heavy chain IIa [Homo sapiens]
Length = 1941
Score = 1114 bits (2882), Expect = 0.0
Identities = 656/1894 (34%), Positives = 1057/1894 (55%), Gaps = 20/1894 (1%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V + E F+ G+I+ +V V+ + +T+ D V NPPK+DKIEDM+ +T+L
Sbjct: 39 FVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHL 97
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y +++ ++GKKR E PPHIF+
Sbjct: 98 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFS 157
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVA--GATRNKSLNAAAQQN 621
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A G + + + + Q
Sbjct: 158 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQ- 216
Query: 622 IVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGAN 801
G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+
Sbjct: 217 -----------GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASAD 265
Query: 802 IEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLP 975
IE YLLEKSRV+ Q + ERS+HIFYQI E E LL + +Y F+ I++
Sbjct: 266 IETYLLEKSRVVFQLKAERSYHIFYQITSN-KKPELIEMLLITTNPYDYPFVSQGEISVA 324
Query: 976 NVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVI 1155
++DD +E +T +++ I+GF ++E SI ++ AV+ GNL+F Q+++ +QA V
Sbjct: 325 SIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVA 384
Query: 1156 QKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVT 1335
K +L L +L KA PR+KVG E+V K Q EQ AV A+AKA YE++F W+V
Sbjct: 385 DKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVA 444
Query: 1336 RINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEE 1515
RIN+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEE
Sbjct: 445 RINQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEE 503
Query: 1516 YQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKH 1692
Y++EGIEW FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H K
Sbjct: 504 YKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKS 563
Query: 1693 PKFIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGI 1863
F P + ++++HFA++HYAG VDY+ WL KN DPLNE VVGL Q S +A +
Sbjct: 564 ANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQL 623
Query: 1864 WKDAEFAGICAAEMNETAFGMR---SRKG-MFRTVSQLHKEQLTKLMTTLRNTSPHFVRC 2031
F+G AE G + +KG F+TVS L +E L KLMT LR+T PHFVRC
Sbjct: 624 -----FSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRC 678
Query: 2032 IIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK 2211
IIPN K G + LVL QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L IP+
Sbjct: 679 IIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPE 738
Query: 2212 -NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQC 2388
FID K++ K++ ++DID Y+ G +KVFF+ G+L LEE RD KL LI QA+C
Sbjct: 739 GQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARC 798
Query: 2389 RGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAK 2568
RGFL+R Y N +++ +++W W +LF K+KPLL+ T+ E+
Sbjct: 799 RGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATM 858
Query: 2569 DDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRN 2748
+E + K+ L K E +E E+K+ ++ E+ +Q Q+Q E+E A+ ++ +L
Sbjct: 859 KEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTK 918
Query: 2749 QELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVD 2928
+LE + ++ +R +RK + + +K +
Sbjct: 919 IQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 978
Query: 2929 QXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLH 3108
+ L E++ KAK +LE Q+
Sbjct: 979 NKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVD 1038
Query: 3109 ELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLT 3288
+LE L +E++ + +LE+ KRKL +L+ +++ + + + ++L+ +L K++ E+ + +
Sbjct: 1039 DLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQS 1098
Query: 3289 RYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLD 3468
+ ++E A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L+
Sbjct: 1099 KIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEI-SERLE 1157
Query: 3469 KVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHK 3645
+ AT Q M++K E E +R +E+ E + K + V EL +QI+ +
Sbjct: 1158 EAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQ 1217
Query: 3646 KQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKR 3825
+ + +LEK++++ E D+A + + ++ +++K + E L E+++ E
Sbjct: 1218 RVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLIN 1277
Query: 3826 TLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANIN 4005
L Q R + E +R +E+E + + R + K A +
Sbjct: 1278 DLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAH 1337
Query: 4006 RARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNL 4185
+ + + L ++ EE + +A L++ + A + R K E Q+ EEL +
Sbjct: 1338 ALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKK 1397
Query: 4186 RDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFES 4356
+ + LQ E E + + ++K+++Q E+ED +++E A+ +K+Q+ F+
Sbjct: 1398 KLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDK 1457
Query: 4357 QMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQD 4536
+AE + ++ + +A +E R T + + N + + LE R ++LQQE+ D
Sbjct: 1458 ILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISD 1517
Query: 4537 SISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSE 4716
+ GK +HELEK K+ +E E +++ +EE E +L+ E LR+++ +KSE
Sbjct: 1518 LTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSE 1577
Query: 4717 SDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEV 4896
DR I+ KD E ++ +R ++ + +++ L+ E R ++ A+ +KK+E + E+E QL
Sbjct: 1578 VDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNH 1637
Query: 4897 ANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREA 5076
ANR+ E + QI ++A +++ED+ L +R+ ++AE E+LR
Sbjct: 1638 ANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRAT 1697
Query: 5077 NEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELA 5247
E ++RK Q K++LE I+Q A
Sbjct: 1698 LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNA 1757
Query: 5248 IDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQ 5427
+K +KA + +L E+ + E K+++E++ +D + ++ E E A + Q
Sbjct: 1758 EEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQ 1817
Query: 5428 MAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKS 5607
+ LEA+V+ LE ++ E + A + R+ E+R+ + T Q E++++ + ++L++K
Sbjct: 1818 IQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKL 1877
Query: 5608 NLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
K ++ +RQ +EAE++ + K R +Q E ++
Sbjct: 1878 QAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEE 1911
Score = 157 bits (397), Expect = 3e-36
Identities = 191/929 (20%), Positives = 385/929 (40%), Gaps = 43/929 (4%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + +++ +L + + ELE+ LL E D + + AE + EE +
Sbjct: 853 KEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCD 912
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE N L K+ R ++ EL++D++ E
Sbjct: 913 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKDIDD-------LE 964
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E L + +++ +E A + A +Q ++ +
Sbjct: 965 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1024
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK 3753
+ + K K +QV++L +EQ KK R LE+ + + + + + I ++ + +D+
Sbjct: 1025 TLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDE 1084
Query: 3754 KRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLAT 3933
K K E + +Q+ + E ++ L QL++ EL R+ E EE A R
Sbjct: 1085 KLKKKEFEISNLQSKI----EDEQALGIQLQKKIKELQ--ARIEELEEEIEAERASRAKA 1138
Query: 3934 AXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQG 4113
RL+ A + Q+E +++K EAE
Sbjct: 1139 EKQRSDLSRELEEISERLEEAGGATSAQIE------MNKKREAE---------------- 1176
Query: 4114 AGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELED 4284
+ RR EE+ Q LRKK+ V L +Q++ + K+++ + K +++ E++D
Sbjct: 1177 FQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDD 1236
Query: 4285 SSMELENVRASHRDSEKRQKKFESQMAEER------------VAVQKALLDRDA--MSQE 4422
+ +E V + + EK + E Q++E + + Q+ L ++ S++
Sbjct: 1237 LASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQ 1296
Query: 4423 LRDRETRVLSL-------LNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHEL 4581
L ++E V L +++ +K LEE + + +L LQ S + D + E
Sbjct: 1297 LDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEE 1356
Query: 4582 EKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEK 4761
+++K L+ L ++ EV K E+D AI + E EE
Sbjct: 1357 QESKAELQRAL-------------------SKANTEVAQWRTKYETD-AIQRTE-ELEEA 1395
Query: 4762 RRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXX 4941
++ L ++++ E +E + +++++N++ +L +E N
Sbjct: 1396 KKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNF 1455
Query: 4942 XXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXX 5121
E++ +CEE E R + ++ E+ + E L + K
Sbjct: 1456 DKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEI 1515
Query: 5122 XXXXXXRAKGGGISSE---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQIT 5292
A+GG E K+++E + + +++ E K + Q++L Q+
Sbjct: 1516 SDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVK 1575
Query: 5293 TDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSR--ARAQMAALEAKVQYLED 5466
++ ++R + +K E Q R ++ + L++ +SR A +E + +E
Sbjct: 1576 SE--VDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEI 1633
Query: 5467 QLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDE 5646
QLN + A R R + L DT +D R+ E KE L + L+ +++E
Sbjct: 1634 QLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEE 1693
Query: 5647 AEDEMSRERTKHRNVQREADDLLDANEQL 5733
+ + + ++E LLDA+E++
Sbjct: 1694 LRATLEQTERSRKIAEQE---LLDASERV 1719
Score = 131 bits (329), Expect = 2e-28
Identities = 172/911 (18%), Positives = 377/911 (40%), Gaps = 73/911 (8%)
Frame = +1
Query: 3226 KVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNK 3405
K E ++ EE Q + +E A +K++ + T+ + + D++ + A +
Sbjct: 847 KSAETEKEMATMKEEFQ----KIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAE 902
Query: 3406 AEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEE 3585
E QL K K + K+ E T + +EE+NA ++
Sbjct: 903 GLADAEERCDQLIKTKIQLEAKIKEVTE----RAEDEEEINA--------------ELTA 944
Query: 3586 QKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRK- 3762
+K K + EL I+ + +++EK+++ + + ++ +E+A L + A + K++K
Sbjct: 945 KKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKA 1004
Query: 3763 IHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXX 3942
+ EAH + AE D+ TL + ++D L E+E+ +++R
Sbjct: 1005 LQEAHQQTLDDLQAEEDK-VNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEG 1063
Query: 3943 XXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGE 4122
LK+A +E+EK L ++ ++ E ++L+ +I
Sbjct: 1064 D-------------LKLAQ-ESIMDIENEKQQLDEKLKKKEFEISNLQSKI--------- 1100
Query: 4123 ARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
+ E+++ QL++ K+ +E L++++E ++ + + + + +ELE+ S LE
Sbjct: 1101 ---EDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLE 1157
Query: 4303 NVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNE-VDIMK 4479
+ + KK E++ + R +++A L +A + LR + ++ L E +D ++
Sbjct: 1158 EAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQ 1217
Query: 4480 EHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQ 4659
++ ++ + ++ E+ D SN + K LEK R+LE +L++++ + EE + +
Sbjct: 1218 RVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLIN 1277
Query: 4660 IAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRG---LLKQIRDLENELENEKRGKS 4830
R RL+ + E R + K+ + RG +QI +L+ +LE E + K+
Sbjct: 1278 DLTAQRGRLQTES----GEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKN 1333
Query: 4831 GAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIE--------CEEAR 4986
+ + L +Q E K E +++ + EE
Sbjct: 1334 ALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELE 1393
Query: 4987 QAKEDIAALLREADRKFRAVEAE-------REQLREANEGLMQARKQXXXXXXXXXXXRA 5145
+AK+ +A L+ A+ AV A+ +++L+ E LM ++ +
Sbjct: 1394 EAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQR 1453
Query: 5146 KGGGISSEEKRRLEAKIAQXXXXXXXXQS-NCEL------------AIDKQRKAQVQLEQ 5286
I +E K++ E A+ +S EL ++ ++ L+Q
Sbjct: 1454 NFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQ 1513
Query: 5287 ITTDLSME-----------RTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMA 5433
+DL+ + + ++ E EK L+ + + +A + E E G R + ++
Sbjct: 1514 EISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASL-EHEEGKILRIQLELN 1572
Query: 5434 ALEAKV----------------------QYLEDQLNVEGQEKTAANRAARRLEKRLNDTT 5547
++++V + ++ L+ E + + A R +++E LN+
Sbjct: 1573 QVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEME 1632
Query: 5548 QQFEDEKRANEQA-------KELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREAD 5706
Q R +A + +L+ + + + R ++ +++++ + +Q E +
Sbjct: 1633 IQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIE 1692
Query: 5707 DLLDANEQLTR 5739
+L EQ R
Sbjct: 1693 ELRATLEQTER 1703
Score = 114 bits (285), Expect = 3e-23
Identities = 169/888 (19%), Positives = 349/888 (39%), Gaps = 111/888 (12%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ +E ++ +E++ ++ ++KL + E + +Q +++ E +L LQ
Sbjct: 1059 RKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQ 1118
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + +R S R ++E + + +
Sbjct: 1119 ARIEELEEEIE--AERASRAKAEKQRSDLSR--ELEEISERLEEAGGATSAQIEMNKKRE 1174
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K ++
Sbjct: 1175 AEFQKMRRDLEEATLQHEATAATLRKKHADSVAELG---EQIDNLQRVKQKLEKEKSEMK 1231
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K LE+ R L +L + K E+ + +L Q + E
Sbjct: 1232 MEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESG 1291
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ DE+ A V+ + + + I+EL+ +E E A+N + + ++
Sbjct: 1292 EFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLRE 1351
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
++ + LQ +S+ + EV TK + IQ T E +EE K K +++++ +
Sbjct: 1352 QYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQAAEEH 1409
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME-------I 3789
+E + + LEK + + E D+ ++ A+ A +DKK++ + L E
Sbjct: 1410 VEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEET 1469
Query: 3790 QANLAESDEHKRTLIDQL-------ERSRDELDHLNRVREEEEHAFANMQRRLATAXXXX 3948
A L S + R+L +L E S D+L+ L R + + +++ ++A
Sbjct: 1470 HAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRI 1529
Query: 3949 XXXXXXXXXXTR----LKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGA 4116
+ L+ A LE E+ +L + E +++ ++++I +
Sbjct: 1530 HELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEI 1589
Query: 4117 GEARR---KAEESVNQQLE----------ELRKKNLRDVEHLQKQLEESEVAKERILQSK 4257
+ +R + ES+ L+ L+KK D+ ++ QL + L++
Sbjct: 1590 DQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNY 1649
Query: 4258 KKIQQELEDSSMELENVRASHRDS-------EKRQKKFESQMAEERVAVQKALLDRDAMS 4416
+ Q L+D+ + L++ S D E+R ++++ E R +++ R
Sbjct: 1650 RNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAE 1709
Query: 4417 QELRDRETRV-------LSLLN-----EVDI------MKEHLEESDRVRRSLQQELQDSI 4542
QEL D RV SL+N E DI M++ L+E+ ++ + D+
Sbjct: 1710 QELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAA 1769
Query: 4543 SNKDDFGKNVH---ELEKAKRSLEAELNDMRVQMEELED------NLQIAE-DARLR--- 4683
++ K LE+ K+++E + D++++++E E QI + +AR+R
Sbjct: 1770 MMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELE 1829
Query: 4684 ---------------------LEVTNQALKSESDR------------------AISNKDV 4746
V ++E DR + +
Sbjct: 1830 GEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAE 1889
Query: 4747 EAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
EAEE+ L + R L++ELE + A S K+ + E+ ++
Sbjct: 1890 EAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKV 1937
>gi|24584694|ref|NP_724000.1| CG17927-PG [Drosophila melanogaster]
gi|22946660|gb|AAN10960.1| CG17927-PG [Drosophila melanogaster]
Length = 1962
Score = 1114 bits (2881), Expect = 0.0
Identities = 674/1916 (35%), Positives = 1077/1916 (56%), Gaps = 31/1916 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K CW+PD+ EG+L+G IK D V V L + I + V+K NPPKF+KIEDM++
Sbjct: 35 KKSCWIPDEKEGYLLGEIKATKGDIVSVGLQGGEVR-DIKSEKVEKVNPPKFEKIEDMAD 93
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
+T LN VLHNL+ RYY+ LIYTYSGLFCV INPYK+ P+Y+ + ++GK+R+E+PP
Sbjct: 94 MTVLNTPCVLHNLRQRYYAKLIYTYSGLFCVAINPYKRYPVYTNRCAKMYRGKRRNEVPP 153
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIFAI+D AY ML +QS+L TGESGAGKTENTKKVI Y A V +K + AA+
Sbjct: 154 HIFAISDGAYVDMLTNHVNQSMLITGESGAGKTENTKKVIAYFATVGA---SKKTDEAAK 210
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
G LE Q++Q NP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++G
Sbjct: 211 SK-----------GSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFGPTGKLAG 259
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLL-EGVDNYRFLVNRGITL 972
A+IE YLLEK+RV+ Q ERS+HIFYQI+ G K LL + + +Y + +T+
Sbjct: 260 ADIETYLLEKARVISQQSLERSYHIFYQIMSGSVPGVKDICLLTDNIYDYHIVSQGKVTV 319
Query: 973 PNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRV 1152
++DD +EF T + I+GF E + R+ +AV+ +G ++F Q + +QA +
Sbjct: 320 ASIDDAEEFSLTDQAFDILGFTKQEKEDVYRITAAVMHMGGMKFKQRGREEQAEQDGEEE 379
Query: 1153 IQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLV 1332
+V L G EL K L+PRIKVG EFV + +N +Q ++ A+ K ++RLFKWLV
Sbjct: 380 GGRVSKLFGCDTAELYKNLLKPRIKVGNEFVTQGRNVQQVTNSIGALCKGVFDRLFKWLV 439
Query: 1333 TRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQE 1512
+ N++LD T ++ FIG+LDIAGFEIF+ N FEQ+CIN+TNEKLQQ FN+ MF+LEQE
Sbjct: 440 KKCNETLD-TQQKRQHFIGVLDIAGFEIFEYNGFEQLCINFTNEKLQQFFNHHMFVLEQE 498
Query: 1513 EYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NK 1689
EY+REGI+W FIDFG+DL IDLIEKPMG+L++L+EE +FPKA D++F EKL TH K
Sbjct: 499 EYKREGIDWAFIDFGMDLLACIDLIEKPMGILSILEEESMFPKATDQTFSEKLTNTHLGK 558
Query: 1690 HPKFIVPDM----RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVA 1857
F P + +HFA+ HYAG V Y+ WL KN DPLN+ VV + S + +
Sbjct: 559 SAPFQKPKPPKPGQQAAHFAIAHYAGCVSYNITGWLEKNKDPLNDTVVDQFKKSQNKLLI 618
Query: 1858 GIWKDAEFAGICAAEMNETAFGMRSRK-GMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCI 2034
I+ A+ AG E A G R +K G F TVS +KEQL LMTTLR+T PHFVRCI
Sbjct: 619 EIF--ADHAGQSGG--GEQAKGGRGKKGGGFATVSSAYKEQLNSLMTTLRSTQPHFVRCI 674
Query: 2035 IPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKN 2214
IPN K+ G ++++LV+ QL CNGVLEGIRICR+GFPNR+ + +F+ RY+I+ P ++ +
Sbjct: 675 IPNEMKQPGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKMRYKIMCPKLL-QG 733
Query: 2215 FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRG 2394
K++ +I +D+ + YR+G +KVFFR GVL +EE RD +L ++ QA RG
Sbjct: 734 VEKDKKATEIIIKFIDLPEDQYRLGNTKVFFRAGVLGQMEEFRDERLGKIMSWMQAWARG 793
Query: 2395 FLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDD 2574
+LSR+ + N YL+LR W W++L+ KVKPLL V+R +DEI A+ +
Sbjct: 794 YLSRKGFKKLQEQRVALKVVQRNLRKYLQLRTWPWYKLWQKVKPLLNVSRIEDEI-ARLE 852
Query: 2575 ELRATKERLLKMEHDFRENEKKLD-QVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQ 2751
E E L E R+ + L+ +++ E+ + + L E + + +L +
Sbjct: 853 EKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQDYQERNAKLTAQKN 912
Query: 2752 ELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQ 2931
+LE + D+++RL+ ++K + + DK D
Sbjct: 913 DLENQLRDIQERLTQEEDARNQLFQQKKKADQEISGLKKDIEDLELNVQKAEQDKATKDH 972
Query: 2932 XXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHE 3111
+ + +L E++ H K K +LE L E
Sbjct: 973 QIRNLNDEIAHQDELINKLNKEKKMQGETNQKTGEELQAAEDKINHLNKVKAKLEQTLDE 1032
Query: 3112 LEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTR 3291
LE L RE++ + ++E+ KRK+ +L+ +++ +A+ +EL + ++D+EL +
Sbjct: 1033 LEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVADLERNKKELEQTIQRKDKELSSITAK 1092
Query: 3292 YDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDK 3471
++E V Q+Q++++Q I+EL E++E ER AR KAE R ++ +LE++ G+ L++
Sbjct: 1093 LEDEQVVVLKHQRQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEEL-GERLEE 1151
Query: 3472 VDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKK 3648
AT Q +L +++ E++ +R +E+ E + + K + V E+ +Q++Q K
Sbjct: 1152 AGGATSAQIELNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNK 1211
Query: 3649 QRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRT 3828
+++ EK++N+ + D+ + + +A +K K + L E+Q+ L DE RT
Sbjct: 1212 LKAKAEKEKNEYYGQLNDLRAGVDHITNEKAAQEKIAKQLQHTLNEVQSKL---DETNRT 1268
Query: 3829 LIDQLERSRDEL----DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIA 3996
L D + S+ +L L R EE E + + + + +R +
Sbjct: 1269 LND-FDASKKKLSIENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERAT 1327
Query: 3997 NINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHAARQGAGEARRKAEE---SVNQQLE 4164
+ + R LE + + L ++ +EEAEG +A L++++ A A R K E + +++LE
Sbjct: 1328 LLGKFRNLEHDLDNLREQVEEEAEG-KADLQRQLSKANAEAQVWRSKYESDGVARSEELE 1386
Query: 4165 ELRKKNLRDVEHLQKQLEESEVAKERILQ-------SKKKIQQELEDSSMELENVRASHR 4323
E ++K LQ +L E+E E + Q +K+++ E+ED +E++ A
Sbjct: 1387 EAKRK-------LQARLAEAEETIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIAN 1439
Query: 4324 DSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDR 4503
+EK+QK F+ + E ++ V + DA +E R+ T + L + +E LE R
Sbjct: 1440 AAEKKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRR 1499
Query: 4504 VRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLR 4683
++L E++D + + G+N+HE+EKA++ LEAE ++++ +EE E L+ E+ LR
Sbjct: 1500 ENKNLADEVKDLLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLR 1559
Query: 4684 LEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIEN 4863
++ ++ E DR I K+ E E R+ + + ++ LE E +GK+ A+ +KK+E
Sbjct: 1560 AQLELSQVRQEIDRRIQEKEEEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEA 1619
Query: 4864 QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRA 5043
I ELE L+ AN+ E + Q EE ++A++D L ++R+ A
Sbjct: 1620 DINELEIALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANA 1679
Query: 5044 VEAEREQ----LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXX 5211
++ E E+ L +A+ G QA ++ A+ IS+ KR+LE+++
Sbjct: 1680 LQNELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISA-AKRKLESELQTLHS 1738
Query: 5212 XXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITE 5391
+ + + +K +KA V ++ +L E+ Q E +++LE+ ++ + ++ E
Sbjct: 1739 DLDELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDE 1798
Query: 5392 LESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKR 5571
E+ A + + LE +V+ LE++L+ E + A + R+ E+R+ + + Q E++++
Sbjct: 1799 AEANALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRK 1858
Query: 5572 ANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQR---EADDLLDANEQ 5730
+E+ ++L++K K + +RQ++EAE+ + K R Q+ EA++ D EQ
Sbjct: 1859 NHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQ 1914
Score = 155 bits (391), Expect = 1e-35
Identities = 179/950 (18%), Positives = 386/950 (39%), Gaps = 62/950 (6%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDE 3267
RLE + + E+ E + + ELE KLLAE D L+ + G +++
Sbjct: 850 RLEEKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQD---------- 899
Query: 3268 ELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEK 3447
Y E +A +T Q D++ + +++E + E +ARN+ +++ ++
Sbjct: 900 --------YQERNAKLTA---QKNDLENQLRDIQERLTQEEDARNQLFQQKKKADQEISG 948
Query: 3448 VKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+K D+ D + + KD ++ I Q + K+ ++K ++ +
Sbjct: 949 LKKDIEDLELNVQKAEQDKATKDHQIRNLNDEIAH-QDELINKLNKEKKMQGETNQKTGE 1007
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAE 3807
+++ + + + L K + + +Q ++ + + R D++K ++ E L Q +A+
Sbjct: 1008 ELQAAEDKINHLNKVKAKLEQTLDELEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVAD 1067
Query: 3808 SDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL 3987
+ +K+ L ++R EL + E+E+ QR++
Sbjct: 1068 LERNKKELEQTIQRKDKELSSITAKLEDEQVVVLKHQRQIKELQA--------------- 1112
Query: 3988 KIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEE 4167
R +LE+E A + +AE RA L +E+ + GE +A + + Q+E
Sbjct: 1113 ------RIEELEEEVEAERQARAKAEKQRADLAREL----EELGERLEEAGGATSAQIE- 1161
Query: 4168 LRKKNLRDVEHLQKQLEESEVAKERILQS-KKKIQQELEDSSMELENVRASHRDSEKRQK 4344
L KK ++ L++ LEE+ + E L + +KK + + + +++ + +EK +
Sbjct: 1162 LNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNKLKAKAEKEKN 1221
Query: 4345 KFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQ 4524
++ Q+ + R V ++ A + + + + + +++D L + D ++ L
Sbjct: 1222 EYYGQLNDLRAGVDHITNEKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSI 1281
Query: 4525 ELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE--------------LE---DN 4653
E D + ++ V +L K K SL +L D + +E LE DN
Sbjct: 1282 ENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERATLLGKFRNLEHDLDN 1341
Query: 4654 L--QIAEDARLRLEVTNQALKSESDRAISNKDVEA---------EEKRRGLLKQIRDLEN 4800
L Q+ E+A + ++ Q K+ ++ + E+ EE +R L ++ + E
Sbjct: 1342 LREQVEEEAEGKADLQRQLSKANAEAQVWRSKYESDGVARSEELEEAKRKLQARLAEAEE 1401
Query: 4801 ELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEE 4980
+E+ + G ++++ ++ +L+ +++ AN + E++++ ++
Sbjct: 1402 TIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIANAAEKKQKAFDKIIGEWKLKVDD 1461
Query: 4981 ARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGG-G 5157
+ R + ++ E+ +E E + + K +GG
Sbjct: 1462 LAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGRN 1521
Query: 5158 ISSEEK--RRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKT 5331
I EK +RLEA+ + ++ E +K +AQ++L Q+ ++ +R + +K
Sbjct: 1522 IHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEI--DRRIQEKE 1579
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRARA--QMAALEAKVQYLEDQLNVEGQEKTAAN 5505
E + + + R + LE+ A+ +A A LEA + LE L+ + A
Sbjct: 1580 EEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQ 1639
Query: 5506 RAARRLEKRLNDTTQQFEDEKR----------------------------ANEQAKELLE 5601
+ +R +++L D E+E+R EQA
Sbjct: 1640 KNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRR 1699
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
++ + + QL+E + + R ++ E L ++L E N
Sbjct: 1700 QAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDELLNEAKN 1749
Score = 82.4 bits (202), Expect = 1e-13
Identities = 82/418 (19%), Positives = 183/418 (43%), Gaps = 25/418 (5%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L +Q+ E ++++ + + LE K +L A LE+++ L ++ KV +L + +E
Sbjct: 1511 LLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQE 1570
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ ++ +EE N ++ Q +D ++ +E E + +A ++++ A + ++
Sbjct: 1571 IDRRIQEKEEEFENTR------KNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINEL 1624
Query: 3451 KGDVLDKVDEATM-LQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+ LD ++A Q + R +++ + A+E+ Q + EQ R+ L +
Sbjct: 1625 E-IALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDA-REQLGISERRANALQN 1682
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL-- 3801
++E+ + Q ++ + QA+QE AD +++ + A A I ++ E+ L + ++L
Sbjct: 1683 ELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDE 1742
Query: 3802 ----AESDEHKRT--------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
A++ E K L D+L +D ++R+ E +Q RL A
Sbjct: 1743 LLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAEAN 1802
Query: 3946 XXXXXXXXXXXTRLKIANIN------RARQLEDEKNALLDEKEEAE-GLRAHLEKEIHAA 4104
++ + + R + +KN E+ E ++ +++ H
Sbjct: 1803 ALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRKNHER 1862
Query: 4105 RQGAGEARRKAEESVNQQLEELRK---KNLRDVEHLQKQLEESEVAKERILQSKKKIQ 4269
Q + ++ ++ +Q+EE + NL Q++LEE+E + Q+ K +
Sbjct: 1863 MQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQAISKFR 1920
>gi|24584716|ref|NP_724010.1| CG17927-PM [Drosophila melanogaster]
gi|22946671|gb|AAN10970.1| CG17927-PM [Drosophila melanogaster]
Length = 1936
Score = 1113 bits (2880), Expect = 0.0
Identities = 678/1916 (35%), Positives = 1072/1916 (55%), Gaps = 31/1916 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K CW+PD+ EG+L+G IK D V V L + + +D +Q+ NPPK++K EDMS
Sbjct: 35 KKSCWIPDEKEGYLLGEIKATKGDIVSVGLQGGETR-DLKKDLLQQVNPPKYEKAEDMSN 93
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LTYLN+ASVLHNL+ RYY+ LIYTYSGLFCV INPYK+ P+Y+ + ++GK+R+E+PP
Sbjct: 94 LTYLNDASVLHNLRQRYYNKLIYTYSGLFCVAINPYKRYPVYTNRCAKMYRGKRRNEVPP 153
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIFAI+D AY ML +QS+L TGESGAGKTENTKKVI Y A V +K + AA+
Sbjct: 154 HIFAISDGAYVDMLTNHVNQSMLITGESGAGKTENTKKVIAYFATVGA---SKKTDEAAK 210
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
G LE Q++Q NP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++G
Sbjct: 211 SK-----------GSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFGPTGKLAG 259
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSE-YLLEGVDNYRFLVNRGITL 972
A+IE YLLEK+RV+ Q ERS+HIFYQI+ G K +L + + +Y + +T+
Sbjct: 260 ADIETYLLEKARVISQQSLERSYHIFYQIMSGSVPGVKEMCFLSDNIYDYYNVSQGKVTV 319
Query: 973 PNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRV 1152
PN+DD +EF + I+GF E + R+ +AV+ +G ++F Q + +QA +
Sbjct: 320 PNMDDGEEFQLADQAFDILGFTKQEKEDVYRITAAVMHMGGMKFKQRGREEQAEQDGEEE 379
Query: 1153 IQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLV 1332
+V L G EL K L+PRIKVG EFV + +N +Q ++ A+ K ++RLFKWLV
Sbjct: 380 GGRVSKLFGCDTAELYKNLLKPRIKVGNEFVTQGRNVQQVTNSIGALCKGVFDRLFKWLV 439
Query: 1333 TRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQE 1512
+ N++LD T ++ FIG+LDIAGFEIF+ N FEQ+CIN+TNEKLQQ FN+ MF+LEQE
Sbjct: 440 KKCNETLD-TQQKRQHFIGVLDIAGFEIFEYNGFEQLCINFTNEKLQQFFNHHMFVLEQE 498
Query: 1513 EYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NK 1689
EY+REGI+W FIDFG+DL IDLIEKPMG+L++L+EE +FPKA D++F EKL TH K
Sbjct: 499 EYKREGIDWAFIDFGMDLLACIDLIEKPMGILSILEEESMFPKATDQTFSEKLTNTHLGK 558
Query: 1690 HPKFIVPDM----RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVA 1857
F P + +HFA+ HYAG V Y+ WL KN DPLN+ VV + S + +
Sbjct: 559 SAPFQKPKPPKPGQQAAHFAIAHYAGCVSYNITGWLEKNKDPLNDTVVDQFKKSQNKLLI 618
Query: 1858 GIWKDAEFAGICAAEMNETAFGMRSRK-GMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCI 2034
I+ A+ AG E A G R +K G F TVS +KEQL LMTTLR+T PHFVRCI
Sbjct: 619 EIF--ADHAGQSGG--GEQAKGGRGKKGGGFATVSSAYKEQLNSLMTTLRSTQPHFVRCI 674
Query: 2035 IPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKN 2214
IPN K+ G ++++LV+ QL CNGVLEGIRICR+GFPNR+ + +F+ RY+IL P I
Sbjct: 675 IPNEMKQPGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKMRYQILNPAGI-VG 733
Query: 2215 FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRG 2394
D K+ ++ + +D ++YRIG +KVFFR GVL +EE RD +L ++ QA RG
Sbjct: 734 VDDPKKCGSIILESTALDPDMYRIGHTKVFFRAGVLGQMEEFRDERLGKIMSWMQAWARG 793
Query: 2395 FLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDD 2574
+LSR+ + N YL+LR W W++L+ KVKPLL V+R +DEI A+ +
Sbjct: 794 YLSRKGFKKLQEQRVALKVVQRNLRKYLQLRTWPWYKLWQKVKPLLNVSRIEDEI-ARLE 852
Query: 2575 ELRATKERLLKMEHDFRENEKKLD-QVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQ 2751
E E L E R+ + L+ +++ E+ + + L E + + +L +
Sbjct: 853 EKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQDYQERNAKLTAQKN 912
Query: 2752 ELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQ 2931
+LE + D+++RL+ ++K + + DK D
Sbjct: 913 DLENQLRDIQERLTQEEDARNQLFQQKKKADQEISGLKKDIEDLELNVQKAEQDKATKDH 972
Query: 2932 XXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHE 3111
+ + +L E++ H K K +LE L E
Sbjct: 973 QIRNLNDEIAHQDELINKLNKEKKMQGETNQKTGEELQAAEDKINHLNKVKAKLEQTLDE 1032
Query: 3112 LEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTR 3291
LE L RE++ + ++E+ KRK+ +L+ +++ +A+ +EL + ++D+EL +
Sbjct: 1033 LEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVADLERNKKELEQTIQRKDKELSSITAK 1092
Query: 3292 YDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDK 3471
++E V Q+Q++++Q I+EL E++E ER AR KAE R ++ +LE++ G+ L++
Sbjct: 1093 LEDEQVVVLKHQRQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEEL-GERLEE 1151
Query: 3472 VDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKK 3648
AT Q +L +++ E++ +R +E+ E + + K + V E+ +Q++Q K
Sbjct: 1152 AGGATSAQIELNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNK 1211
Query: 3649 QRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRT 3828
+++ E + E L +A +K K + L E+Q+ L DE RT
Sbjct: 1212 LKAKAEHDRQTCHNELNQTRTACDQLGRDKAAQEKIAKQLQHTLNEVQSKL---DETNRT 1268
Query: 3829 LIDQLERSRDEL----DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIA 3996
L D + S+ +L L R EE E + + + + +R +
Sbjct: 1269 LND-FDASKKKLSIENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERAT 1327
Query: 3997 NINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHAARQGAGEARRKAEE---SVNQQLE 4164
+ + R LE + + L ++ +EEAEG +A L++++ A A R K E + +++LE
Sbjct: 1328 LLGKFRNLEHDLDNLREQVEEEAEG-KADLQRQLSKANAEAQVWRSKYESDGVARSEELE 1386
Query: 4165 ELRKKNLRDVEHLQKQLEESEVAKERILQ-------SKKKIQQELEDSSMELENVRASHR 4323
E ++K LQ +L E+E E + Q +K+++ E+ED +E++ A
Sbjct: 1387 EAKRK-------LQARLAEAEETIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIAN 1439
Query: 4324 DSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDR 4503
+EK+QK F+ + E ++ V + DA +E R+ T + L + +E LE R
Sbjct: 1440 AAEKKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRR 1499
Query: 4504 VRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLR 4683
++L E++D + + G+N+HE+EKA++ LEAE ++++ +EE E L+ E+ LR
Sbjct: 1500 ENKNLADEVKDLLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLR 1559
Query: 4684 LEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIEN 4863
++ ++ E DR I K+ E E R+ + + ++ LE E +GK+ A+ +KK+E
Sbjct: 1560 AQLELSQVRQEIDRRIQEKEEEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEA 1619
Query: 4864 QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRA 5043
I ELE L+ AN+ E + Q EE ++A++D L ++R+ A
Sbjct: 1620 DINELEIALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANA 1679
Query: 5044 VEAEREQ----LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXX 5211
++ E E+ L +A+ G QA ++ A+ IS+ KR+LE+++
Sbjct: 1680 LQNELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISA-AKRKLESELQTLHS 1738
Query: 5212 XXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITE 5391
+ + + +K +KA V ++ +L E+ Q E +++LE+ ++ + ++ E
Sbjct: 1739 DLDELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDE 1798
Query: 5392 LESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKR 5571
E+ A + + LE +V+ LE++L+ E + A + R+ E+R+ + + Q E++++
Sbjct: 1799 AEANALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRK 1858
Query: 5572 ANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQR---EADDLLDANEQ 5730
+E+ ++L++K K + +RQ++EAE+ + K R Q+ EA++ D EQ
Sbjct: 1859 NHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQ 1914
Score = 151 bits (382), Expect = 2e-34
Identities = 178/950 (18%), Positives = 386/950 (39%), Gaps = 62/950 (6%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDE 3267
RLE + + E+ E + + ELE KLLAE D L+ + G +++
Sbjct: 850 RLEEKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQD---------- 899
Query: 3268 ELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEK 3447
Y E +A +T Q D++ + +++E + E +ARN+ +++ ++
Sbjct: 900 --------YQERNAKLTA---QKNDLENQLRDIQERLTQEEDARNQLFQQKKKADQEISG 948
Query: 3448 VKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+K D+ D + + KD ++ I Q + K+ ++K ++ +
Sbjct: 949 LKKDIEDLELNVQKAEQDKATKDHQIRNLNDEIAH-QDELINKLNKEKKMQGETNQKTGE 1007
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAE 3807
+++ + + + L K + + +Q ++ + + R D++K ++ E L Q +A+
Sbjct: 1008 ELQAAEDKINHLNKVKAKLEQTLDELEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVAD 1067
Query: 3808 SDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL 3987
+ +K+ L ++R EL + E+E+ QR++
Sbjct: 1068 LERNKKELEQTIQRKDKELSSITAKLEDEQVVVLKHQRQIKELQA--------------- 1112
Query: 3988 KIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEE 4167
R +LE+E A + +AE RA L +E+ + GE +A + + Q+E
Sbjct: 1113 ------RIEELEEEVEAERQARAKAEKQRADLAREL----EELGERLEEAGGATSAQIE- 1161
Query: 4168 LRKKNLRDVEHLQKQLEESEVAKERILQS-KKKIQQELEDSSMELENVRASHRDSEKRQK 4344
L KK ++ L++ LEE+ + E L + +KK + + + +++ + +E ++
Sbjct: 1162 LNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNKLKAKAEHDRQ 1221
Query: 4345 KFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQ 4524
+++ + R A + D+ A + + + + + +++D L + D ++ L
Sbjct: 1222 TCHNELNQTRTACDQLGRDKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSI 1281
Query: 4525 ELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE--------------LE---DN 4653
E D + ++ V +L K K SL +L D + +E LE DN
Sbjct: 1282 ENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERATLLGKFRNLEHDLDN 1341
Query: 4654 L--QIAEDARLRLEVTNQALKSESDRAISNKDVEA---------EEKRRGLLKQIRDLEN 4800
L Q+ E+A + ++ Q K+ ++ + E+ EE +R L ++ + E
Sbjct: 1342 LREQVEEEAEGKADLQRQLSKANAEAQVWRSKYESDGVARSEELEEAKRKLQARLAEAEE 1401
Query: 4801 ELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEE 4980
+E+ + G ++++ ++ +L+ +++ AN + E++++ ++
Sbjct: 1402 TIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIANAAEKKQKAFDKIIGEWKLKVDD 1461
Query: 4981 ARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGG-G 5157
+ R + ++ E+ +E E + + K +GG
Sbjct: 1462 LAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGRN 1521
Query: 5158 ISSEEK--RRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKT 5331
I EK +RLEA+ + ++ E +K +AQ++L Q+ ++ +R + +K
Sbjct: 1522 IHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEI--DRRIQEKE 1579
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRARA--QMAALEAKVQYLEDQLNVEGQEKTAAN 5505
E + + + R + LE+ A+ +A A LEA + LE L+ + A
Sbjct: 1580 EEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQ 1639
Query: 5506 RAARRLEKRLNDTTQQFEDEKR----------------------------ANEQAKELLE 5601
+ +R +++L D E+E+R EQA
Sbjct: 1640 KNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRR 1699
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
++ + + QL+E + + R ++ E L ++L E N
Sbjct: 1700 QAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDELLNEAKN 1749
Score = 82.4 bits (202), Expect = 1e-13
Identities = 82/418 (19%), Positives = 183/418 (43%), Gaps = 25/418 (5%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L +Q+ E ++++ + + LE K +L A LE+++ L ++ KV +L + +E
Sbjct: 1511 LLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQE 1570
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ ++ +EE N ++ Q +D ++ +E E + +A ++++ A + ++
Sbjct: 1571 IDRRIQEKEEEFENTR------KNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINEL 1624
Query: 3451 KGDVLDKVDEATM-LQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+ LD ++A Q + R +++ + A+E+ Q + EQ R+ L +
Sbjct: 1625 E-IALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDA-REQLGISERRANALQN 1682
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL-- 3801
++E+ + Q ++ + QA+QE AD +++ + A A I ++ E+ L + ++L
Sbjct: 1683 ELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDE 1742
Query: 3802 ----AESDEHKRT--------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
A++ E K L D+L +D ++R+ E +Q RL A
Sbjct: 1743 LLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAEAN 1802
Query: 3946 XXXXXXXXXXXTRLKIANIN------RARQLEDEKNALLDEKEEAE-GLRAHLEKEIHAA 4104
++ + + R + +KN E+ E ++ +++ H
Sbjct: 1803 ALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRKNHER 1862
Query: 4105 RQGAGEARRKAEESVNQQLEELRK---KNLRDVEHLQKQLEESEVAKERILQSKKKIQ 4269
Q + ++ ++ +Q+EE + NL Q++LEE+E + Q+ K +
Sbjct: 1863 MQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQAISKFR 1920
>gi|13560269|dbj|BAB40920.1| myosin heavy chain 2a [Bos taurus]
Length = 1940
Score = 1113 bits (2880), Expect = 0.0
Identities = 653/1895 (34%), Positives = 1056/1895 (55%), Gaps = 21/1895 (1%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V + E F+ G+I+ +V V+ + +T+ D V NPPKFDKIEDM+ +T+L
Sbjct: 39 FVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKEDQVFPMNPPKFDKIEDMAMMTHL 97
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 98 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFS 157
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVA--GATRNKSLNAAAQQN 621
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A G + + + + Q
Sbjct: 158 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKEEITSGKIQ- 216
Query: 622 IVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGAN 801
G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+
Sbjct: 217 -----------GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASAD 265
Query: 802 IEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLP 975
IE YLLEKSRV Q + ERS+HIFYQI E E LL + +Y F+ I++
Sbjct: 266 IETYLLEKSRVTFQLKAERSYHIFYQITSN-RKPELIEMLLITTNPYDYPFISQGEISVA 324
Query: 976 NVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVI 1155
++DD +E +T +++ I+GF ++E SI ++ AV+ GNL+F Q+++ +QA V
Sbjct: 325 SIDDQEELIATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVA 384
Query: 1156 QKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVT 1335
K +L L +L KA PR+KVG E+V K Q EQ AV A+AKA YE++F W+V
Sbjct: 385 DKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVTNAVGALAKAVYEKMFLWMVA 444
Query: 1336 RINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEE 1515
RIN+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEE
Sbjct: 445 RINQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEE 503
Query: 1516 YQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKH 1692
Y+REGIEW FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H K
Sbjct: 504 YKREGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDMSFKNKLYDQHLGKS 563
Query: 1693 PKFIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGI 1863
F P + + ++HFA++HYAG VDY+ WL KN DPLN+ VVGL Q S +A +
Sbjct: 564 ANFQKPKVVKGKPEAHFALIHYAGVVDYNITGWLEKNKDPLNDTVVGLYQKSALKTLAFL 623
Query: 1864 WK-----DAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVR 2028
+ D+E +G T G + + F+TVS L +E L KLMT LR+T PHFVR
Sbjct: 624 FSGTPTGDSEASG-------GTKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVR 676
Query: 2029 CIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIP 2208
CIIPN K G + LVL QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L IP
Sbjct: 677 CIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIP 736
Query: 2209 K-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQ 2385
+ +ID K++ K++ ++DID Y+ G +KVFF+ G+L LEE RD KL L+ QA+
Sbjct: 737 EGQYIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLMTRTQAR 796
Query: 2386 CRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRA 2565
CRGFL+R Y N A++ +++W W +LF ++KPLL+ T+ E+
Sbjct: 797 CRGFLARVEYQKMVERRESIFCIQYNIRAFMNVKHWPWMKLFFRIKPLLKSAETEKEMAT 856
Query: 2566 KDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTR 2745
+E + TK+ L K E +E E+K+ ++ E+ +Q Q+Q E+E A+ ++ +L
Sbjct: 857 MKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEAEGLADAEERCDQLIKT 916
Query: 2746 NQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNV 2925
+LE + ++ +R +RK + + +K
Sbjct: 917 KIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHAT 976
Query: 2926 DQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQL 3105
+ + L E++ KAK +LE Q+
Sbjct: 977 ENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQV 1036
Query: 3106 HELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQL 3285
+LE L +E++ + +LE+ KRKL +L+ +++ + + + ++L+ +L K++ E+ +
Sbjct: 1037 DDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQ 1096
Query: 3286 TRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVL 3465
++ ++E A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L
Sbjct: 1097 SKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEI-SERL 1155
Query: 3466 DKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQH 3642
++ AT Q M++K E E +R +E+ E + K + V EL +QI+
Sbjct: 1156 EEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 1215
Query: 3643 KKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHK 3822
++ + +LEK++++ E D+A + + ++ +++K + E + E+++ E
Sbjct: 1216 QRVKQKLEKEKSEMKMEIDDLASNVETISKAKGNLEKMCRTLEDQVNELKSKEEEQQRLI 1275
Query: 3823 RTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANI 4002
L Q R + E +R +E+E + + R + K A
Sbjct: 1276 NDLTTQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALA 1335
Query: 4003 NRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN 4182
+ + + + L ++ EE + +A L++ + A + R K E Q+ EEL +
Sbjct: 1336 HGLQSARHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAK 1395
Query: 4183 LRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFE 4353
+ + LQ E E + + ++K+++Q E+ED +++E A+ +K+Q+ F+
Sbjct: 1396 KKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFD 1455
Query: 4354 SQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQ 4533
+AE + ++ + +A +E R T + + N + + LE R ++LQQE+
Sbjct: 1456 KILAEWKQKYEETHAELEAAQKEARSLGTELFKMKNAYEESLDQLETLKRENKNLQQEIS 1515
Query: 4534 DSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKS 4713
D + GK +HELEK K+ +E E ++++ +EE E +L+ E LR+++ +KS
Sbjct: 1516 DLTEQIAEGGKRMHELEKIKKQVEQEKSEIQAALEEAEASLEHEEGKILRIQLELNQVKS 1575
Query: 4714 ESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLE 4893
E DR I+ KD E ++ +R ++ + ++ L+ E R ++ A+ +KK+E + E+E QL
Sbjct: 1576 EIDRKIAEKDEEIDQLKRNHIRVVESMQTMLDAEIRSRNDAIRLKKKMEGDLNEMEIQLN 1635
Query: 4894 VANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLRE 5073
ANR+ E + QI ++A + +ED+ L +R+ ++AE E+LR
Sbjct: 1636 HANRMAAEALKNYRNTQAILKDTQIHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRA 1695
Query: 5074 ANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCEL 5244
E ++RK Q K++LE I Q
Sbjct: 1696 TLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDITQIQGEMEDILQEARN 1755
Query: 5245 AIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARA 5424
A +K +KA + +L E+ + E K+++E++ +D + ++ E E A +
Sbjct: 1756 AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQNRLDEAEQLALKGGKK 1815
Query: 5425 QMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEK 5604
Q+ LEA+V+ LE ++ E + A + R+ E+R+ + T Q E++++ + ++L++K
Sbjct: 1816 QIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDK 1875
Query: 5605 SNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
K ++ +RQ +EAE++ + +K R +Q E ++
Sbjct: 1876 LQAKVKSYKRQAEEAEEQSNTNLSKFRKLQHELEE 1910
Score = 152 bits (385), Expect = 7e-35
Identities = 193/922 (20%), Positives = 383/922 (40%), Gaps = 36/922 (3%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + + + +L + + ELE+ LL E D + + AE + EE +
Sbjct: 852 KEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEAEGLADAEERCD 911
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE N L K+ R ++ EL++D++ E
Sbjct: 912 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKDIDD-------LE 963
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E L + +++ +E A + A +Q ++ +
Sbjct: 964 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1023
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK 3753
+ + K K +QV++L +EQ KK R LE+ + + + + + I ++ + +D+
Sbjct: 1024 TLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDE 1083
Query: 3754 KRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLAT 3933
K K E + +Q+ + E ++ L QL++ EL R+ E EE A R
Sbjct: 1084 KLKKKEFEISNLQSKI----EDEQALGIQLQKKIKELQ--ARIEELEEEIEAERASRAKA 1137
Query: 3934 AXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQG 4113
RL+ A + Q+E +++K EAE
Sbjct: 1138 EKQRSDLSRELEEISERLEEAGGATSAQIE------MNKKREAE---------------- 1175
Query: 4114 AGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELED 4284
+ RR EE+ Q LRKK+ V L +Q++ + K+++ + K +++ E++D
Sbjct: 1176 FQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDD 1235
Query: 4285 SSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQEL-RDRETRVLSLLN 4461
+ +E + + + EK + E Q+ E L ++ Q L D T+ L
Sbjct: 1236 LASNVETISKAKGNLEKMCRTLEDQVNE--------LKSKEEEQQRLINDLTTQRGRLQT 1287
Query: 4462 EVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE 4641
E L+E + + L + Q ++ + + E KAK +L L R +
Sbjct: 1288 ESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHGLQSARHDCDL 1347
Query: 4642 LEDNLQIAEDARLRL---------EVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDL 4794
L + + ++++ L EV K E+D AI + E EE ++ L ++++
Sbjct: 1348 LREQYEEEQESKAELQRALSKANTEVAQWRTKYETD-AIQRTE-ELEEAKKKLAQRLQAA 1405
Query: 4795 ENELENEKRGKSGAVSHRKKIENQIGELEQQLEVAN----RLKEEYXXXXXXXXXXXXEY 4962
E +E + +++++N++ +L +E N L ++ +Y
Sbjct: 1406 EEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKY 1465
Query: 4963 QIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXR 5142
+ E A+++ +L E + A E +QL E L + K
Sbjct: 1466 EETHAELEAAQKEARSLGTELFKMKNAYEESLDQL----ETLKRENKNLQQEISDLTEQI 1521
Query: 5143 AKGGGISSE---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMER 5313
A+GG E K+++E + ++ +++ E K + Q++L Q+ +++ +R
Sbjct: 1522 AEGGKRMHELEKIKKQVEQEKSEIQAALEEAEASLEHEEGKILRIQLELNQVKSEI--DR 1579
Query: 5314 TLNQKTEAEKQSLERSNRDYKAKITELESGAQSR--ARAQMAALEAKVQYLEDQLNVEGQ 5487
+ +K E Q R ++ T L++ +SR A +E + +E QLN +
Sbjct: 1580 KIAEKDEEIDQLKRNHIRVVESMQTMLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANR 1639
Query: 5488 EKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSR 5667
A + R + L DT +D R E KE L + L+ +++E + +
Sbjct: 1640 MAAEALKNYRNTQAILKDTQIHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQ 1699
Query: 5668 ERTKHRNVQREADDLLDANEQL 5733
+ ++E LLDA+E++
Sbjct: 1700 TERSRKIAEQE---LLDASERV 1718
Score = 124 bits (311), Expect = 3e-26
Identities = 138/758 (18%), Positives = 312/758 (40%), Gaps = 47/758 (6%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + ++ D++ + + +R +LE++ +E+ D+ ++ AD ++
Sbjct: 851 EKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEAEGLADAEERC 910
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ + +E L + + DE L + ++ E A ++
Sbjct: 911 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 970
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ K A N+ + L +E L +E +K +
Sbjct: 971 KE---------------------KHATENKVKNLTEEMAGL----DETIAKLTKEKKALQ 1005
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
A Q + + E+ VN L + + K + V+ L+ LE+ + + + ++K+K++ +L
Sbjct: 1006 EAHQQTLDDLQAEEDKVNT-LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDL 1064
Query: 4279 ---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL 4449
++S M++EN + D + ++K+FE + ++ ++AL + +++++ + R+
Sbjct: 1065 KLAQESIMDIENEK-QQLDEKLKKKEFEISNLQSKIEDEQAL--GIQLQKKIKELQARIE 1121
Query: 4450 SLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRV 4629
L E++ + ++++ R L +EL++ ++ G + + EAE MR
Sbjct: 1122 ELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR 1181
Query: 4630 QME----------------------ELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
+E EL + + + + +LE +K E D SN
Sbjct: 1182 DLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASN-- 1239
Query: 4744 VEAEEKRRGLLK--------QIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
VE K +G L+ Q+ +L+++ E ++R + + R +++ + GE +QL+
Sbjct: 1240 VETISKAKGNLEKMCRTLEDQVNELKSKEEEQQRLINDLTTQRGRLQTESGEFSRQLDEK 1299
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA----DRKFRAVEAEREQL 5067
L + E + + EE +AK +A L+ A D E E+E
Sbjct: 1300 EALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHGLQSARHDCDLLREQYEEEQESK 1359
Query: 5068 REANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELA 5247
E L +A + + E K++L ++ + C
Sbjct: 1360 AELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASL 1419
Query: 5248 IDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES---GAQSRA 5418
+++ Q ++E + D+ + ++++ ++ ++K K E + AQ A
Sbjct: 1420 EKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKYEETHAELEAAQKEA 1479
Query: 5419 RAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELL 5598
R+ L E+ L+ + R + L++ ++D T+Q + + + +++
Sbjct: 1480 RSLGTELFKMKNAYEESLD----QLETLKRENKNLQQEISDLTEQIAEGGKRMHELEKIK 1535
Query: 5599 EKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
++ + ++ L+EAE + E K +Q E + +
Sbjct: 1536 KQVEQEKSEIQAALEEAEASLEHEEGKILRIQLELNQV 1573
Score = 110 bits (276), Expect = 3e-22
Identities = 165/888 (18%), Positives = 347/888 (38%), Gaps = 111/888 (12%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ +E ++ +E++ ++ ++KL + E + +Q +++ E +L LQ
Sbjct: 1058 RKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQ 1117
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + +R S R ++E + + +
Sbjct: 1118 ARIEELEEEIE--AERASRAKAEKQRSDLSR--ELEEISERLEEAGGATSAQIEMNKKRE 1173
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K ++
Sbjct: 1174 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELG---EQIDNLQRVKQKLEKEKSEMK 1230
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K LE+ R L ++ + K E+ + +L Q + E
Sbjct: 1231 MEIDDLASNVETISKAKGNLEKMCRTLEDQVNELKSKEEEQQRLINDLTTQRGRLQTESG 1290
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ DE+ A V+ + + + I+EL+ +E E A+N + + ++
Sbjct: 1291 EFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHGLQSARHDCDLLRE 1350
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
++ + LQ +S+ + EV TK + IQ T E +EE K K +++++ +
Sbjct: 1351 QYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQAAEEH 1408
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME-------I 3789
+E + + LEK + + E D+ ++ A+ A +DKK++ + L E
Sbjct: 1409 VEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKYEET 1468
Query: 3790 QANLAESDEHKRTLIDQL-------ERSRDELDHLNRVREEEEHAFANMQRRLATAXXXX 3948
A L + + R+L +L E S D+L+ L R + + +++ ++A
Sbjct: 1469 HAELEAAQKEARSLGTELFKMKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRM 1528
Query: 3949 XXXXXXXXXX----TRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGA 4116
+ ++ A LE E+ +L + E +++ ++++I +
Sbjct: 1529 HELEKIKKQVEQEKSEIQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEI 1588
Query: 4117 GEARR---KAEESVNQQLE----------ELRKKNLRDVEHLQKQLEESEVAKERILQSK 4257
+ +R + ES+ L+ L+KK D+ ++ QL + L++
Sbjct: 1589 DQLKRNHIRVVESMQTMLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALKNY 1648
Query: 4258 KKIQQELEDSSMELENVRASHRDS-------EKRQKKFESQMAEERVAVQKALLDRDAMS 4416
+ Q L+D+ + L++ D E+R ++++ E R +++ R
Sbjct: 1649 RNTQAILKDTQIHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAE 1708
Query: 4417 QELRDRETRV-------LSLLN-----EVDI------MKEHLEESDRVRRSLQQELQDSI 4542
QEL D RV SL+N E DI M++ L+E+ ++ + D+
Sbjct: 1709 QELLDASERVQLLHTQNTSLINTKKKLETDITQIQGEMEDILQEARNAEEKAKKAITDAA 1768
Query: 4543 SNKDDFGKNVH---ELEKAKRSLEAELNDMRVQMEELED------NLQIAE-DARLR--- 4683
++ K LE+ K+++E + D++ +++E E QI + +AR+R
Sbjct: 1769 MMAEELKKEQDTSAHLERMKKNMEQTVKDLQNRLDEAEQLALKGGKKQIQKLEARVRELE 1828
Query: 4684 ---------------------LEVTNQALKSESDR------------------AISNKDV 4746
V ++E DR + +
Sbjct: 1829 GEVESEQKRNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAE 1888
Query: 4747 EAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
EAEE+ L + R L++ELE + A S K+ + E+ ++
Sbjct: 1889 EAEEQSNTNLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKI 1936
>gi|24584710|ref|NP_724007.1| CG17927-PB [Drosophila melanogaster]
gi|22946668|gb|AAN10967.1| CG17927-PB [Drosophila melanogaster]
Length = 1962
Score = 1113 bits (2880), Expect = 0.0
Identities = 678/1916 (35%), Positives = 1072/1916 (55%), Gaps = 31/1916 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K CW+PD+ EG+L+G IK D V V L + + +D +Q+ NPPK++K EDMS
Sbjct: 35 KKSCWIPDEKEGYLLGEIKATKGDIVSVGLQGGETR-DLKKDLLQQVNPPKYEKAEDMSN 93
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LTYLN+ASVLHNL+ RYY+ LIYTYSGLFCV INPYK+ P+Y+ + ++GK+R+E+PP
Sbjct: 94 LTYLNDASVLHNLRQRYYNKLIYTYSGLFCVAINPYKRYPVYTNRCAKMYRGKRRNEVPP 153
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIFAI+D AY ML +QS+L TGESGAGKTENTKKVI Y A V +K + AA+
Sbjct: 154 HIFAISDGAYVDMLTNHVNQSMLITGESGAGKTENTKKVIAYFATVGA---SKKTDEAAK 210
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
G LE Q++Q NP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++G
Sbjct: 211 SK-----------GSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFGPTGKLAG 259
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSE-YLLEGVDNYRFLVNRGITL 972
A+IE YLLEK+RV+ Q ERS+HIFYQI+ G K +L + + +Y + +T+
Sbjct: 260 ADIETYLLEKARVISQQSLERSYHIFYQIMSGSVPGVKEMCFLSDNIYDYYNVSQGKVTV 319
Query: 973 PNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRV 1152
PN+DD +EF + I+GF E + R+ +AV+ +G ++F Q + +QA +
Sbjct: 320 PNMDDGEEFQLADQAFDILGFTKQEKEDVYRITAAVMHMGGMKFKQRGREEQAEQDGEEE 379
Query: 1153 IQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLV 1332
+V L G EL K L+PRIKVG EFV + +N +Q ++ A+ K ++RLFKWLV
Sbjct: 380 GGRVSKLFGCDTAELYKNLLKPRIKVGNEFVTQGRNVQQVTNSIGALCKGVFDRLFKWLV 439
Query: 1333 TRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQE 1512
+ N++LD T ++ FIG+LDIAGFEIF+ N FEQ+CIN+TNEKLQQ FN+ MF+LEQE
Sbjct: 440 KKCNETLD-TQQKRQHFIGVLDIAGFEIFEYNGFEQLCINFTNEKLQQFFNHHMFVLEQE 498
Query: 1513 EYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NK 1689
EY+REGI+W FIDFG+DL IDLIEKPMG+L++L+EE +FPKA D++F EKL TH K
Sbjct: 499 EYKREGIDWAFIDFGMDLLACIDLIEKPMGILSILEEESMFPKATDQTFSEKLTNTHLGK 558
Query: 1690 HPKFIVPDM----RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVA 1857
F P + +HFA+ HYAG V Y+ WL KN DPLN+ VV + S + +
Sbjct: 559 SAPFQKPKPPKPGQQAAHFAIAHYAGCVSYNITGWLEKNKDPLNDTVVDQFKKSQNKLLI 618
Query: 1858 GIWKDAEFAGICAAEMNETAFGMRSRK-GMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCI 2034
I+ A+ AG E A G R +K G F TVS +KEQL LMTTLR+T PHFVRCI
Sbjct: 619 EIF--ADHAGQSGG--GEQAKGGRGKKGGGFATVSSAYKEQLNSLMTTLRSTQPHFVRCI 674
Query: 2035 IPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKN 2214
IPN K+ G ++++LV+ QL CNGVLEGIRICR+GFPNR+ + +F+ RY+IL P I
Sbjct: 675 IPNEMKQPGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKMRYQILNPAGI-VG 733
Query: 2215 FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRG 2394
D K+ ++ + +D ++YRIG +KVFFR GVL +EE RD +L ++ QA RG
Sbjct: 734 VDDPKKCGSIILESTALDPDMYRIGHTKVFFRAGVLGQMEEFRDERLGKIMSWMQAWARG 793
Query: 2395 FLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDD 2574
+LSR+ + N YL+LR W W++L+ KVKPLL V+R +DEI A+ +
Sbjct: 794 YLSRKGFKKLQEQRVALKVVQRNLRKYLQLRTWPWYKLWQKVKPLLNVSRIEDEI-ARLE 852
Query: 2575 ELRATKERLLKMEHDFRENEKKLD-QVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQ 2751
E E L E R+ + L+ +++ E+ + + L E + + +L +
Sbjct: 853 EKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQDYQERNAKLTAQKN 912
Query: 2752 ELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQ 2931
+LE + D+++RL+ ++K + + DK D
Sbjct: 913 DLENQLRDIQERLTQEEDARNQLFQQKKKADQEISGLKKDIEDLELNVQKAEQDKATKDH 972
Query: 2932 XXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHE 3111
+ + +L E++ H K K +LE L E
Sbjct: 973 QIRNLNDEIAHQDELINKLNKEKKMQGETNQKTGEELQAAEDKINHLNKVKAKLEQTLDE 1032
Query: 3112 LEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTR 3291
LE L RE++ + ++E+ KRK+ +L+ +++ +A+ +EL + ++D+EL +
Sbjct: 1033 LEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVADLERNKKELEQTIQRKDKELSSITAK 1092
Query: 3292 YDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDK 3471
++E V Q+Q++++Q I+EL E++E ER AR KAE R ++ +LE++ G+ L++
Sbjct: 1093 LEDEQVVVLKHQRQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEEL-GERLEE 1151
Query: 3472 VDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKK 3648
AT Q +L +++ E++ +R +E+ E + + K + V E+ +Q++Q K
Sbjct: 1152 AGGATSAQIELNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNK 1211
Query: 3649 QRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRT 3828
+++ E + E L +A +K K + L E+Q+ L DE RT
Sbjct: 1212 LKAKAEHDRQTCHNELNQTRTACDQLGRDKAAQEKIAKQLQHTLNEVQSKL---DETNRT 1268
Query: 3829 LIDQLERSRDEL----DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIA 3996
L D + S+ +L L R EE E + + + + +R +
Sbjct: 1269 LND-FDASKKKLSIENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERAT 1327
Query: 3997 NINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHAARQGAGEARRKAEE---SVNQQLE 4164
+ + R LE + + L ++ +EEAEG +A L++++ A A R K E + +++LE
Sbjct: 1328 LLGKFRNLEHDLDNLREQVEEEAEG-KADLQRQLSKANAEAQVWRSKYESDGVARSEELE 1386
Query: 4165 ELRKKNLRDVEHLQKQLEESEVAKERILQ-------SKKKIQQELEDSSMELENVRASHR 4323
E ++K LQ +L E+E E + Q +K+++ E+ED +E++ A
Sbjct: 1387 EAKRK-------LQARLAEAEETIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIAN 1439
Query: 4324 DSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDR 4503
+EK+QK F+ + E ++ V + DA +E R+ T + L + +E LE R
Sbjct: 1440 AAEKKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRR 1499
Query: 4504 VRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLR 4683
++L E++D + + G+N+HE+EKA++ LEAE ++++ +EE E L+ E+ LR
Sbjct: 1500 ENKNLADEVKDLLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLR 1559
Query: 4684 LEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIEN 4863
++ ++ E DR I K+ E E R+ + + ++ LE E +GK+ A+ +KK+E
Sbjct: 1560 AQLELSQVRQEIDRRIQEKEEEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEA 1619
Query: 4864 QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRA 5043
I ELE L+ AN+ E + Q EE ++A++D L ++R+ A
Sbjct: 1620 DINELEIALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANA 1679
Query: 5044 VEAEREQ----LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXX 5211
++ E E+ L +A+ G QA ++ A+ IS+ KR+LE+++
Sbjct: 1680 LQNELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISA-AKRKLESELQTLHS 1738
Query: 5212 XXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITE 5391
+ + + +K +KA V ++ +L E+ Q E +++LE+ ++ + ++ E
Sbjct: 1739 DLDELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDE 1798
Query: 5392 LESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKR 5571
E+ A + + LE +V+ LE++L+ E + A + R+ E+R+ + + Q E++++
Sbjct: 1799 AEANALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRK 1858
Query: 5572 ANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQR---EADDLLDANEQ 5730
+E+ ++L++K K + +RQ++EAE+ + K R Q+ EA++ D EQ
Sbjct: 1859 NHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQ 1914
Score = 151 bits (382), Expect = 2e-34
Identities = 178/950 (18%), Positives = 386/950 (39%), Gaps = 62/950 (6%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDE 3267
RLE + + E+ E + + ELE KLLAE D L+ + G +++
Sbjct: 850 RLEEKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQD---------- 899
Query: 3268 ELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEK 3447
Y E +A +T Q D++ + +++E + E +ARN+ +++ ++
Sbjct: 900 --------YQERNAKLTA---QKNDLENQLRDIQERLTQEEDARNQLFQQKKKADQEISG 948
Query: 3448 VKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+K D+ D + + KD ++ I Q + K+ ++K ++ +
Sbjct: 949 LKKDIEDLELNVQKAEQDKATKDHQIRNLNDEIAH-QDELINKLNKEKKMQGETNQKTGE 1007
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAE 3807
+++ + + + L K + + +Q ++ + + R D++K ++ E L Q +A+
Sbjct: 1008 ELQAAEDKINHLNKVKAKLEQTLDELEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVAD 1067
Query: 3808 SDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL 3987
+ +K+ L ++R EL + E+E+ QR++
Sbjct: 1068 LERNKKELEQTIQRKDKELSSITAKLEDEQVVVLKHQRQIKELQA--------------- 1112
Query: 3988 KIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEE 4167
R +LE+E A + +AE RA L +E+ + GE +A + + Q+E
Sbjct: 1113 ------RIEELEEEVEAERQARAKAEKQRADLAREL----EELGERLEEAGGATSAQIE- 1161
Query: 4168 LRKKNLRDVEHLQKQLEESEVAKERILQS-KKKIQQELEDSSMELENVRASHRDSEKRQK 4344
L KK ++ L++ LEE+ + E L + +KK + + + +++ + +E ++
Sbjct: 1162 LNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNKLKAKAEHDRQ 1221
Query: 4345 KFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQ 4524
+++ + R A + D+ A + + + + + +++D L + D ++ L
Sbjct: 1222 TCHNELNQTRTACDQLGRDKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSI 1281
Query: 4525 ELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE--------------LE---DN 4653
E D + ++ V +L K K SL +L D + +E LE DN
Sbjct: 1282 ENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERATLLGKFRNLEHDLDN 1341
Query: 4654 L--QIAEDARLRLEVTNQALKSESDRAISNKDVEA---------EEKRRGLLKQIRDLEN 4800
L Q+ E+A + ++ Q K+ ++ + E+ EE +R L ++ + E
Sbjct: 1342 LREQVEEEAEGKADLQRQLSKANAEAQVWRSKYESDGVARSEELEEAKRKLQARLAEAEE 1401
Query: 4801 ELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEE 4980
+E+ + G ++++ ++ +L+ +++ AN + E++++ ++
Sbjct: 1402 TIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIANAAEKKQKAFDKIIGEWKLKVDD 1461
Query: 4981 ARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGG-G 5157
+ R + ++ E+ +E E + + K +GG
Sbjct: 1462 LAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGRN 1521
Query: 5158 ISSEEK--RRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKT 5331
I EK +RLEA+ + ++ E +K +AQ++L Q+ ++ +R + +K
Sbjct: 1522 IHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEI--DRRIQEKE 1579
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRARA--QMAALEAKVQYLEDQLNVEGQEKTAAN 5505
E + + + R + LE+ A+ +A A LEA + LE L+ + A
Sbjct: 1580 EEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQ 1639
Query: 5506 RAARRLEKRLNDTTQQFEDEKR----------------------------ANEQAKELLE 5601
+ +R +++L D E+E+R EQA
Sbjct: 1640 KNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRR 1699
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
++ + + QL+E + + R ++ E L ++L E N
Sbjct: 1700 QAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDELLNEAKN 1749
Score = 82.4 bits (202), Expect = 1e-13
Identities = 82/418 (19%), Positives = 183/418 (43%), Gaps = 25/418 (5%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L +Q+ E ++++ + + LE K +L A LE+++ L ++ KV +L + +E
Sbjct: 1511 LLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQE 1570
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ ++ +EE N ++ Q +D ++ +E E + +A ++++ A + ++
Sbjct: 1571 IDRRIQEKEEEFENTR------KNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINEL 1624
Query: 3451 KGDVLDKVDEATM-LQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+ LD ++A Q + R +++ + A+E+ Q + EQ R+ L +
Sbjct: 1625 E-IALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDA-REQLGISERRANALQN 1682
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL-- 3801
++E+ + Q ++ + QA+QE AD +++ + A A I ++ E+ L + ++L
Sbjct: 1683 ELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDE 1742
Query: 3802 ----AESDEHKRT--------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
A++ E K L D+L +D ++R+ E +Q RL A
Sbjct: 1743 LLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAEAN 1802
Query: 3946 XXXXXXXXXXXTRLKIANIN------RARQLEDEKNALLDEKEEAE-GLRAHLEKEIHAA 4104
++ + + R + +KN E+ E ++ +++ H
Sbjct: 1803 ALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRKNHER 1862
Query: 4105 RQGAGEARRKAEESVNQQLEELRK---KNLRDVEHLQKQLEESEVAKERILQSKKKIQ 4269
Q + ++ ++ +Q+EE + NL Q++LEE+E + Q+ K +
Sbjct: 1863 MQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQAISKFR 1920
>gi|37360930|dbj|BAC98374.1| KIAA2034 protein [Homo sapiens]
Length = 1571
Score = 1113 bits (2878), Expect = 0.0
Identities = 609/1514 (40%), Positives = 915/1514 (60%), Gaps = 44/1514 (2%)
Frame = +1
Query: 1336 RINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEE 1515
R+N++LDR+ RQGASF+GILDIAGFEIF +NSFEQ+CINYTNEKLQQLFN+TMF+LEQEE
Sbjct: 1 RLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEE 60
Query: 1516 YQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDEECLFPKANDKSFVEKLQKTHN 1686
YQREGI W F+DFGLDLQP IDLIE+P G+LALLDEEC FPKA DKSFVEK+ +
Sbjct: 61 YQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQG 120
Query: 1687 KHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGI 1863
HPKF P +R ++ F+V+HYAG+VDY A++WLMKNMDPLN+NV L+ STD A I
Sbjct: 121 GHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 180
Query: 1864 WKDAE-------------------------------FAGICAAE----MNETAFGMRSRK 1938
WKD GI E + + G R R+
Sbjct: 181 WKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRR 240
Query: 1939 GMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEG 2118
GMFRTV QL+KE L++LM TL NT+P FVRCI+PNHEK++GK+ LVL+QLRCNGVLEG
Sbjct: 241 GMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEG 300
Query: 2119 IRICRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSK 2298
IRICRQGFPNR+ FQEFR RYEILTP+ IPK F+DGK++ KMI AL++D NLYR+GQSK
Sbjct: 301 IRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSK 360
Query: 2299 VFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYL 2478
+FFR GVLA LEEERDLK+T +I++FQA RG+L+RR + N AYL
Sbjct: 361 IFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYL 420
Query: 2479 KLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIV 2658
KLR+WQWWRLFTKVKPLLQVTR D+ ++A+ EL+ +E + + E + ++ Q+
Sbjct: 421 KLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEE 480
Query: 2659 ERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRK 2838
ERA + EQL+ E+E AE ++ RGRL R QELE +V+++ R+ +++
Sbjct: 481 ERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKR 540
Query: 2839 QMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXX 3018
+ +++ +K + +D
Sbjct: 541 LQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDR 600
Query: 3019 XXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDS 3198
++Q + EE+ K K + + E + ++E L +E + + ELE+ KR+L E +
Sbjct: 601 LAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSEL 660
Query: 3199 KDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDM 3378
++ + E+ + EEL QL +++EELQ L R ++E + K +R+ Q + E +ED+
Sbjct: 661 QEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDL 720
Query: 3379 ETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQ 3558
E+ER AR KAE RR++ +LE ++G++ D +D Q+L S++++EV K+ +E+
Sbjct: 721 ESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEET 780
Query: 3559 HTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASR 3738
E ++E + + + + EL +Q+EQ ++ + EK + + E +++ E++ LQ +R
Sbjct: 781 RIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTAR 840
Query: 3739 ADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
+ +++R+ E L E+Q + + + ++L+R++ EL++++ E E +
Sbjct: 841 QEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLS 900
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ L++ TR K+A +R R +E E L ++ EE R +E+
Sbjct: 901 KELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQ 960
Query: 4099 AARQGAGEARRKAEESVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQ 4272
A+ E RR+ EE + EE R++ R+ E L ++L E +R+ + ++++QQ
Sbjct: 961 TAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQ 1020
Query: 4273 ELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLS 4452
EL+D++M+LE R EK+Q+KF+ +AEE+ AV +A+ +R+ E R+RE R LS
Sbjct: 1021 ELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALS 1080
Query: 4453 LLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQ 4632
L ++ +E EE +R R+L+ EL+ +S+KDD GK+VHELE+A R E ND+R Q
Sbjct: 1081 LTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQ 1140
Query: 4633 MEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELEN 4812
+ ELED L AEDA+LRLEVT QALK++ +R + +D EE+RR L KQ+RD E E +
Sbjct: 1141 VTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDE 1200
Query: 4813 EKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQA 4992
E++ ++ AV+ RKK+E ++ EL+ Q+ A + KEE E E EE R +
Sbjct: 1201 ERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTS 1260
Query: 4993 KEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGG---GIS 5163
+E+I + RE++++ + +EAE +L+E +AR+Q A G
Sbjct: 1261 REEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAI 1320
Query: 5164 SEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEK 5343
EEKR+LE ++ Q QSN EL D+ RK +Q+E +TT+LS ER+ + K E+ +
Sbjct: 1321 LEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGR 1380
Query: 5344 QSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRL 5523
Q LER ++ + ++ E ++GA++R + +AALE+K+ E+QL E +E+ + + RR
Sbjct: 1381 QQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRA 1440
Query: 5524 EKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREA 5703
EKRL + Q E+E+R +Q ++ LEK NL+ + L+RQL+EAE+E SR + R +QRE
Sbjct: 1441 EKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQREL 1500
Query: 5704 DDLLDANEQLTREL 5745
+D+ ++ E + RE+
Sbjct: 1501 EDVTESAESMNREV 1514
>gi|11024712|ref|NP_060003.1| myosin, heavy polypeptide 4, skeletal
muscle [Homo sapiens]
gi|13431724|sp|Q9Y623|MYH4_HUMAN Myosin heavy chain, skeletal muscle,
fetal (Myosin heavy chain IIb) (MyHC-IIb)
gi|4808811|gb|AAD29949.1| myosin heavy chain IIb [Homo sapiens]
Length = 1939
Score = 1112 bits (2877), Expect = 0.0
Identities = 654/1889 (34%), Positives = 1049/1889 (54%), Gaps = 15/1889 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V D E ++ ++ +V + + VT+ D V NPPK+DKIEDM+ +T+L
Sbjct: 39 FVVDPKESYVKAIVQSREGGKVTAK-TEAGATVTVKEDQVFSMNPPKYDKIEDMAMMTHL 97
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 98 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFS 157
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A K
Sbjct: 158 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKK---------- 207
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
++P G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 208 EEPASGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIE 267
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRF-LVNRG-ITLPNV 981
YLLEKSRV Q + ERS+HIFYQIL E E LL + Y F V++G IT+P++
Sbjct: 268 TYLLEKSRVTFQLKAERSYHIFYQILSN-KKPELIEMLLITTNPYDFAFVSQGEITVPSI 326
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
DD +E +T +++ I+GF DE +I ++ AV+ GN++F Q+++ +QA V K
Sbjct: 327 DDQEELMATDSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADK 386
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L L +L K+ PR+KVG EFV K Q +Q AV A+AKA YE++F W+VTRI
Sbjct: 387 AAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVTRI 446
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 447 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL + H K
Sbjct: 506 KEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNN 565
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P + ++HF++VHYAG VDY+ WL KN DPLNE VVGL Q S +A ++
Sbjct: 566 FQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLAFLFS 625
Query: 1870 DAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHE 2049
A+ A AE G + + F+TVS L +E L KLMT LR+T PHFVRCIIPN
Sbjct: 626 GAQTA---EAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 682
Query: 2050 KKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDG 2226
K G + LVL QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L IP+ FID
Sbjct: 683 KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDS 742
Query: 2227 KESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSR 2406
K++ K++ +++ID Y+ G +KVFF+ G+L LEE RD KL LI QA CRGFL R
Sbjct: 743 KKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAICRGFLMR 802
Query: 2407 RLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRA 2586
+ N A++ +++W W +L+ K+KPLL+ T+ E+ +E
Sbjct: 803 VEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFEK 862
Query: 2587 TKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYI 2766
TKE L K E +E E+K+ ++ E+ +Q Q+Q E++ A+ ++ +L +LE
Sbjct: 863 TKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEAK 922
Query: 2767 VNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXX 2946
+ ++ +R +RK + + +K +
Sbjct: 923 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 982
Query: 2947 XXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDL 3126
+ L E++ KAK +LE Q+ +LE L
Sbjct: 983 TEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSL 1042
Query: 3127 NRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEES 3306
+E++ +LE+ KRKL +L+ +++ + ++LN +L K++ E+ + + ++E
Sbjct: 1043 EQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQ 1102
Query: 3307 ANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT 3486
A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L++ AT
Sbjct: 1103 ALAMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEI-SERLEEAGGAT 1161
Query: 3487 MLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQL 3663
Q +L +++ E +R +E+ E + K + V EL QI+ ++ + +L
Sbjct: 1162 SAQIELNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGKQIDSLQRVKQKL 1221
Query: 3664 EKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQL 3843
EK++++ E D+A + + ++A+ +K + E L EI+ E L Q
Sbjct: 1222 EKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQK 1281
Query: 3844 ERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLE 4023
R E +R +E++ + + R T+ K + +
Sbjct: 1282 ARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSAR 1341
Query: 4024 DEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHL 4203
+ + L ++ EE + +A L++ + A + R K E Q+ EEL + + + L
Sbjct: 1342 HDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1401
Query: 4204 QKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEER 4374
Q E E + + ++K+++Q E+ED +++E A+ +K+Q+ F+ +AE +
Sbjct: 1402 QDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWK 1461
Query: 4375 VAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKD 4554
++ + +A +E R T + + N + +HLE R ++LQQE+ D
Sbjct: 1462 QKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIA 1521
Query: 4555 DFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAIS 4734
+ GK++HELEK K+ L+ E ++++ +EE E +L+ E LR+++ +KSE DR I+
Sbjct: 1522 EGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIA 1581
Query: 4735 NKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKE 4914
KD E ++ +R L+ + +++ L+ E R ++ A+ +KK+E + E+E QL ANR
Sbjct: 1582 EKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAA 1641
Query: 4915 EYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANE---- 5082
E + Q+ ++A + ++D+ L +R+ ++AE E+LR + E
Sbjct: 1642 EALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTER 1701
Query: 5083 GLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQR 5262
G A ++ + + + K++LE I+Q A +K +
Sbjct: 1702 GRKMAEQELLDASERVQLLHTQNTSLIN-TKKKLETDISQIQGEMEDIVQEARNAEEKAK 1760
Query: 5263 KAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALE 5442
KA + +L E+ + E K+++E++ +D + ++ E E A + Q+ LE
Sbjct: 1761 KAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLGEAEQLALKGGKKQIQKLE 1820
Query: 5443 AKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNR 5622
A+V+ LE ++ E + A + R+ E+R+ + T Q E++++ + ++L++K K +
Sbjct: 1821 ARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVK 1880
Query: 5623 NLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+RQ +EAE++ + K R +Q E ++
Sbjct: 1881 AYKRQAEEAEEQSNVNLAKFRKLQHELEE 1909
Score = 143 bits (361), Expect = 4e-32
Identities = 173/890 (19%), Positives = 371/890 (41%), Gaps = 64/890 (7%)
Frame = +1
Query: 3256 KRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVA 3435
K ++ + + EE A +K++ + T+ + + D++ + A A E
Sbjct: 851 KEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCD 910
Query: 3436 QLEKVKGDVLDKVDEAT--------MLQDLMSRK---DEEVNATKRAIEQIQHTMEGKIE 3582
QL K K + K+ E T + +L ++K ++E + K+ I+ ++ T+ K+E
Sbjct: 911 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTL-AKVE 969
Query: 3583 EQK------------------------AKFSRQVEELH----DQIEQHKKQRSQLEKQQN 3678
++K K + ++E H D ++ + + + L K +
Sbjct: 970 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKT 1029
Query: 3679 QADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRD 3858
+ +Q+ D+ + + D+++ ++ E L Q + +++ K+ L ++L++
Sbjct: 1030 KLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEF 1089
Query: 3859 ELDHLNRVREEEEHAFANMQRRL----ATAXXXXXXXXXXXXXXTRLKIANINRARQLED 4026
E+ +L E+E+ +Q+++ A + + + +R+LE
Sbjct: 1090 EMSNLQGKIEDEQALAMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELE- 1148
Query: 4027 EKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQ---LEELRKKNLRDVE 4197
E + L+E A + L K+ A Q + RR EES Q LRKK+ V
Sbjct: 1149 EISERLEEAGGATSAQIELNKKREAEFQ---KMRRDLEESTLQHEATAAALRKKHADSVA 1205
Query: 4198 HLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERV 4377
L KQ++ + K+++ + K +++ E+ D + +E V + + EK + E Q++E +
Sbjct: 1206 ELGKQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKT 1265
Query: 4378 AVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDD 4557
+ ++ + EL ++ R L E L+E D + L + Q ++
Sbjct: 1266 KEE----EQQRLINELSAQKAR---LHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEE 1318
Query: 4558 FGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRL---------EVTNQALK 4710
+ + E KAK +L L R + L + + ++A+ L EV K
Sbjct: 1319 LKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTK 1378
Query: 4711 SESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
E+D AI + E EE ++ L ++++D E +E + +++++N++ +L +
Sbjct: 1379 YETD-AIQRTE-ELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDV 1436
Query: 4891 EVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLR 5070
E +N E++ + EE + E R + V+ E+
Sbjct: 1437 ERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESL 1496
Query: 5071 EANEGLMQARKQXXXXXXXXXXXRAKGGGISSE---EKRRLEAKIAQXXXXXXXXQSNCE 5241
+ E L + K A+GG E K++L+ + ++ +++ E
Sbjct: 1497 DHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLE 1556
Query: 5242 LAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRAR 5421
K + Q++L Q+ ++ +++K + + L++ R++ + ++S + R
Sbjct: 1557 HEEGKILRIQLELNQVKSE------IDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIR 1610
Query: 5422 AQMAAL------EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQ 5583
++ AL E + +E QLN ++ A R R + L DT +D R +
Sbjct: 1611 SRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDD 1670
Query: 5584 AKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQL 5733
KE L + ++ +++E + R + ++E LLDA+E++
Sbjct: 1671 LKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQE---LLDASERV 1717
Score = 120 bits (301), Expect = 4e-25
Identities = 130/753 (17%), Positives = 313/753 (41%), Gaps = 42/753 (5%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + E+ +++ + + +R +LE++ QE+ D+ ++ + AD ++
Sbjct: 850 EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERC 909
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ + +E L + + DE L + ++ E A ++
Sbjct: 910 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 969
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ K A N+ + L +E L +E +K +
Sbjct: 970 KE---------------------KHATENKVKNLTEEMAGL----DETIAKLTKEKKALQ 1004
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
A Q + + E+ VN L + + K + V+ L+ LE+ + + ++K+K++ +L
Sbjct: 1005 EAHQQTLDDLQMEEDKVNT-LTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDL 1063
Query: 4279 ---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL 4449
++S+M+ EN + + K+ K+FE + ++ ++AL + + +++++ + R+
Sbjct: 1064 KLAQESTMDTENDKQQLNEKLKK-KEFEMSNLQGKIEDEQALAMQ--LQKKIKELQARIE 1120
Query: 4450 SLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRV 4629
L E++ + ++++ R L +EL++ ++ G + + EAE MR
Sbjct: 1121 ELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIELNKKREAEFQKMRR 1180
Query: 4630 QME----------------------ELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
+E EL + + + +LE LK E + SN +
Sbjct: 1181 DLEESTLQHEATAAALRKKHADSVAELGKQIDSLQRVKQKLEKEKSELKMEINDLASNME 1240
Query: 4744 VEAEEKR------RGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANR 4905
++ K R L Q+ +++ + E ++R + + + ++ + GE +QL+ +
Sbjct: 1241 TVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDA 1300
Query: 4906 LKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA----DRKFRAVEAEREQLRE 5073
+ + E + + EE +AK +A L+ A D E E+E E
Sbjct: 1301 MVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAE 1360
Query: 5074 ANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAID 5253
G+ +A + + E K++L ++ S C
Sbjct: 1361 LQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEK 1420
Query: 5254 KQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMA 5433
+++ Q ++E + D+ + ++++ ++ ++K K E ++ ++ ++ +
Sbjct: 1421 TKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEA-SQKESR 1479
Query: 5434 ALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNL 5613
+L ++ +++ R + L++ ++D T+Q + + + +++ ++ +
Sbjct: 1480 SLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDH 1539
Query: 5614 KNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ L+ L+EAE + E K +Q E + +
Sbjct: 1540 EKSELQTSLEEAEASLEHEEGKILRIQLELNQV 1572
Score = 113 bits (282), Expect = 6e-23
Identities = 173/890 (19%), Positives = 356/890 (39%), Gaps = 113/890 (12%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ +E + E+D ++ +KL + E + +Q +++ E + +L LQ
Sbjct: 1057 RKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAMQLQKKIKELQ 1116
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + +R S R ++E + + +
Sbjct: 1117 ARIEELEEEIE--AERASRAKAEKQRSDLSR--ELEEISERLEEAGGATSAQIELNKKRE 1172
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D +R K + K K L+
Sbjct: 1173 AEFQKMRRDLEESTLQHEATAAALRKKHADSVAELG---KQIDSLQRVKQKLEKEKSELK 1229
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++++L ++ + K+ E+ R L +L + K E+ + EL+ Q + E
Sbjct: 1230 MEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESG 1289
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ DE+ A V+ + + + I+EL+ +E E A++ + + ++
Sbjct: 1290 EFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLRE 1349
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
++ + LQ MS+ + EV TK + IQ T E +EE K K ++++++ +
Sbjct: 1350 QYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQDAEEH 1407
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME-------I 3789
+E + + LEK + + E D+ ++ A+ +DKK++ + L E
Sbjct: 1408 VEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEET 1467
Query: 3790 QANLAESDEHKRTLIDQLERSR----DELDHLNRVREEEE-------------------- 3897
QA L S + R+L +L + + + LDHL ++ E +
Sbjct: 1468 QAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHI 1527
Query: 3898 HAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRAR----QLEDEKNALLDEKEE-- 4059
H ++++L + I R + Q++ E + + EK+E
Sbjct: 1528 HELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEL 1587
Query: 4060 ----------AEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN------LRD 4191
E +++ L+ EI + R A ++K E +N+ +L N LR+
Sbjct: 1588 DQLKRNHLRVVESMQSTLDAEIRS-RNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRN 1646
Query: 4192 VEHLQKQLEESEVAKERILQSKKKIQQELED-------SSMELENVRASHRDSEKRQKKF 4350
+ + Q L+++++ + ++ + ++++L E+E +RAS +E+ +K
Sbjct: 1647 LRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMA 1706
Query: 4351 ESQM--AEERVAV----------QKALLDRDAMS---------QELRDRETRVLSLLNEV 4467
E ++ A ERV + K L+ D QE R+ E + + +
Sbjct: 1707 EQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDA 1766
Query: 4468 DIMKEHLEES-------DRVRRSLQQELQD---SISNKDDFG-----KNVHELEKAKRSL 4602
+M E L++ +R++++++Q ++D + + K + +LE R L
Sbjct: 1767 AMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLGEAEQLALKGGKKQIQKLEARVREL 1826
Query: 4603 EAELNDMRVQMEELEDNL------------QIAEDAR--LRLEVTNQALKSESDRAISNK 4740
E+E+ + E L Q ED + LRL+ L+++ +A +
Sbjct: 1827 ESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKV-KAYKRQ 1885
Query: 4741 DVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
EAEE+ L + R L++ELE + A S K+ + E+ ++
Sbjct: 1886 AEEAEEQSNVNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKV 1935
Score = 69.7 bits (169), Expect = 8e-10
Identities = 106/541 (19%), Positives = 216/541 (39%), Gaps = 32/541 (5%)
Frame = +1
Query: 4213 LEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQK- 4389
L+ +E KE +++E E + EL A ++ E++ + + ++ VQ
Sbjct: 844 LKSAETEKEMA-----NMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898
Query: 4390 --ALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNK---- 4551
AL D + +L + ++ + + EV E EE + + +++L+D S
Sbjct: 899 ADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 958
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQA----LKSES 4719
DD + ++EK K + E ++ ++ +M L++ + + L+ +Q L+ E
Sbjct: 959 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEE 1018
Query: 4720 DRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
D+ N +A+ K L +Q+ DLE LE EK+ ++K+E + ++
Sbjct: 1019 DKV--NTLTKAKTK---LEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDT 1073
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREAN 5079
K++ + + E + ED AL + +K + ++A E+L E
Sbjct: 1074 ENDKQQLNEKLK-------KKEFEMSNLQGKIEDEQALAMQLQKKIKELQARIEELEEEI 1126
Query: 5080 EGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQ 5259
E RAK S+ R LE
Sbjct: 1127 EA--------------ERASRAKAEKQRSDLSRELE------------------------ 1148
Query: 5260 RKAQVQLEQITTDLSMERTLNQKTEAE----KQSLERSNRDYKAKIT------------- 5388
+ +LE+ S + LN+K EAE ++ LE S ++A
Sbjct: 1149 -EISERLEEAGGATSAQIELNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAEL 1207
Query: 5389 --ELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAAN--RAARRLEKRLNDTTQQF 5556
+++S + + + + E K++ + N+E K AN + R LE +L++ +
Sbjct: 1208 GKQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKE 1267
Query: 5557 EDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLT 5736
E+++R + + + ++ RQLDE + +S+ + ++ ++L E+ T
Sbjct: 1268 EEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEET 1327
Query: 5737 R 5739
+
Sbjct: 1328 K 1328
>gi|42476190|ref|NP_060004.2| myosin, heavy polypeptide 2, skeletal
muscle, adult [Homo sapiens]
gi|30722305|emb|CAD91136.1| hypothetical protein [Homo sapiens]
Length = 1941
Score = 1112 bits (2875), Expect = 0.0
Identities = 655/1894 (34%), Positives = 1056/1894 (55%), Gaps = 20/1894 (1%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V + E F+ G+I+ +V V+ + +T+ D V NPPK+DKIEDM+ +T+L
Sbjct: 39 FVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHL 97
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y +++ ++GKKR PPHIF+
Sbjct: 98 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQGAPPHIFS 157
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVA--GATRNKSLNAAAQQN 621
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A G + + + + Q
Sbjct: 158 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQ- 216
Query: 622 IVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGAN 801
G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+
Sbjct: 217 -----------GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASAD 265
Query: 802 IEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLP 975
IE YLLEKSRV+ Q + ERS+HIFYQI E E LL + +Y F+ I++
Sbjct: 266 IETYLLEKSRVVFQLKAERSYHIFYQITSN-KKPELIEMLLITTNPYDYPFVSQGEISVA 324
Query: 976 NVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVI 1155
++DD +E +T +++ I+GF ++E SI ++ AV+ GNL+F Q+++ +QA V
Sbjct: 325 SIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVA 384
Query: 1156 QKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVT 1335
K +L L +L KA PR+KVG E+V K Q EQ AV A+AKA YE++F W+V
Sbjct: 385 DKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVA 444
Query: 1336 RINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEE 1515
RIN+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEE
Sbjct: 445 RINQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEE 503
Query: 1516 YQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKH 1692
Y++EGIEW FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H K
Sbjct: 504 YKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKS 563
Query: 1693 PKFIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGI 1863
F P + ++++HFA++HYAG VDY+ WL KN DPLNE VVGL Q S +A +
Sbjct: 564 ANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQL 623
Query: 1864 WKDAEFAGICAAEMNETAFGMR---SRKG-MFRTVSQLHKEQLTKLMTTLRNTSPHFVRC 2031
F+G AE G + +KG F+TVS L +E L KLMT LR+T PHFVRC
Sbjct: 624 -----FSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRC 678
Query: 2032 IIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK 2211
IIPN K G + LVL QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L IP+
Sbjct: 679 IIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPE 738
Query: 2212 -NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQC 2388
FID K++ K++ ++DID Y+ G +KVFF+ G+L LEE RD KL LI QA+C
Sbjct: 739 GQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARC 798
Query: 2389 RGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAK 2568
RGFL+R Y N +++ +++W W +LF K+KPLL+ T+ E+
Sbjct: 799 RGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATM 858
Query: 2569 DDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRN 2748
+E + K+ L K E +E E+K+ ++ E+ +Q Q+Q E+E A+ ++ +L
Sbjct: 859 KEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTK 918
Query: 2749 QELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVD 2928
+LE + ++ +R +RK + + +K +
Sbjct: 919 IQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 978
Query: 2929 QXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLH 3108
+ L E++ KAK +LE Q+
Sbjct: 979 NKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVD 1038
Query: 3109 ELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLT 3288
+LE L +E++ + +LE+ KRKL +L+ +++ + + + ++L+ +L K++ E+ + +
Sbjct: 1039 DLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQS 1098
Query: 3289 RYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLD 3468
+ ++E A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L+
Sbjct: 1099 KIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEI-SERLE 1157
Query: 3469 KVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHK 3645
+ AT Q M++K E E +R +E+ E + K + V EL +QI+ +
Sbjct: 1158 EAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQ 1217
Query: 3646 KQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKR 3825
+ + +LEK++++ E D+A + + ++ +++K + E L E+++ E
Sbjct: 1218 RVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLIN 1277
Query: 3826 TLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANIN 4005
L Q R + E +R +E+E + + R + K A +
Sbjct: 1278 DLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAH 1337
Query: 4006 RARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNL 4185
+ + + L ++ EE + +A L++ + A + R K E Q+ EEL +
Sbjct: 1338 ALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKK 1397
Query: 4186 RDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFES 4356
+ + LQ E E + + ++K+++Q E+ED +++E A+ +K+Q+ F+
Sbjct: 1398 KLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDK 1457
Query: 4357 QMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQD 4536
+AE + ++ + +A +E R T + + N + + LE R ++LQQE+ D
Sbjct: 1458 ILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISD 1517
Query: 4537 SISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSE 4716
+ GK +HELEK K+ +E E +++ +EE E +L+ E LR+++ +KSE
Sbjct: 1518 LTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSE 1577
Query: 4717 SDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEV 4896
DR I+ KD E ++ +R ++ + +++ L+ E R ++ A+ +KK+E + E+E QL
Sbjct: 1578 VDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNH 1637
Query: 4897 ANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREA 5076
ANR+ E + QI ++A +++ED+ L +R+ ++AE E+LR
Sbjct: 1638 ANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRAT 1697
Query: 5077 NEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELA 5247
E ++RK Q K++LE I+Q A
Sbjct: 1698 LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNA 1757
Query: 5248 IDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQ 5427
+K +KA + +L E+ + E K+++E++ +D + ++ E E A + Q
Sbjct: 1758 EEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQ 1817
Query: 5428 MAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKS 5607
+ LEA+V+ LE ++ E + A + R+ E+R+ + T Q E++++ + ++L++K
Sbjct: 1818 IQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKL 1877
Query: 5608 NLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
K ++ +RQ +EAE++ + K R +Q E ++
Sbjct: 1878 QAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEE 1911
Score = 157 bits (397), Expect = 3e-36
Identities = 191/929 (20%), Positives = 385/929 (40%), Gaps = 43/929 (4%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + +++ +L + + ELE+ LL E D + + AE + EE +
Sbjct: 853 KEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCD 912
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE N L K+ R ++ EL++D++ E
Sbjct: 913 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKDIDD-------LE 964
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E L + +++ +E A + A +Q ++ +
Sbjct: 965 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1024
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK 3753
+ + K K +QV++L +EQ KK R LE+ + + + + + I ++ + +D+
Sbjct: 1025 TLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDE 1084
Query: 3754 KRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLAT 3933
K K E + +Q+ + E ++ L QL++ EL R+ E EE A R
Sbjct: 1085 KLKKKEFEISNLQSKI----EDEQALGIQLQKKIKELQ--ARIEELEEEIEAERASRAKA 1138
Query: 3934 AXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQG 4113
RL+ A + Q+E +++K EAE
Sbjct: 1139 EKQRSDLSRELEEISERLEEAGGATSAQIE------MNKKREAE---------------- 1176
Query: 4114 AGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELED 4284
+ RR EE+ Q LRKK+ V L +Q++ + K+++ + K +++ E++D
Sbjct: 1177 FQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDD 1236
Query: 4285 SSMELENVRASHRDSEKRQKKFESQMAEER------------VAVQKALLDRDA--MSQE 4422
+ +E V + + EK + E Q++E + + Q+ L ++ S++
Sbjct: 1237 LASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQ 1296
Query: 4423 LRDRETRVLSL-------LNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHEL 4581
L ++E V L +++ +K LEE + + +L LQ S + D + E
Sbjct: 1297 LDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEE 1356
Query: 4582 EKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEK 4761
+++K L+ L ++ EV K E+D AI + E EE
Sbjct: 1357 QESKAELQRAL-------------------SKANTEVAQWRTKYETD-AIQRTE-ELEEA 1395
Query: 4762 RRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXX 4941
++ L ++++ E +E + +++++N++ +L +E N
Sbjct: 1396 KKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNF 1455
Query: 4942 XXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXX 5121
E++ +CEE E R + ++ E+ + E L + K
Sbjct: 1456 DKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEI 1515
Query: 5122 XXXXXXRAKGGGISSE---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQIT 5292
A+GG E K+++E + + +++ E K + Q++L Q+
Sbjct: 1516 SDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVK 1575
Query: 5293 TDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSR--ARAQMAALEAKVQYLED 5466
++ ++R + +K E Q R ++ + L++ +SR A +E + +E
Sbjct: 1576 SE--VDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEI 1633
Query: 5467 QLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDE 5646
QLN + A R R + L DT +D R+ E KE L + L+ +++E
Sbjct: 1634 QLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEE 1693
Query: 5647 AEDEMSRERTKHRNVQREADDLLDANEQL 5733
+ + + ++E LLDA+E++
Sbjct: 1694 LRATLEQTERSRKIAEQE---LLDASERV 1719
Score = 131 bits (329), Expect = 2e-28
Identities = 172/911 (18%), Positives = 377/911 (40%), Gaps = 73/911 (8%)
Frame = +1
Query: 3226 KVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNK 3405
K E ++ EE Q + +E A +K++ + T+ + + D++ + A +
Sbjct: 847 KSAETEKEMATMKEEFQ----KIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAE 902
Query: 3406 AEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEE 3585
E QL K K + K+ E T + +EE+NA ++
Sbjct: 903 GLADAEERCDQLIKTKIQLEAKIKEVTE----RAEDEEEINA--------------ELTA 944
Query: 3586 QKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRK- 3762
+K K + EL I+ + +++EK+++ + + ++ +E+A L + A + K++K
Sbjct: 945 KKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKA 1004
Query: 3763 IHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXX 3942
+ EAH + AE D+ TL + ++D L E+E+ +++R
Sbjct: 1005 LQEAHQQTLDDLQAEEDK-VNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEG 1063
Query: 3943 XXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGE 4122
LK+A +E+EK L ++ ++ E ++L+ +I
Sbjct: 1064 D-------------LKLAQ-ESIMDIENEKQQLDEKLKKKEFEISNLQSKI--------- 1100
Query: 4123 ARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
+ E+++ QL++ K+ +E L++++E ++ + + + + +ELE+ S LE
Sbjct: 1101 ---EDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLE 1157
Query: 4303 NVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNE-VDIMK 4479
+ + KK E++ + R +++A L +A + LR + ++ L E +D ++
Sbjct: 1158 EAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQ 1217
Query: 4480 EHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQ 4659
++ ++ + ++ E+ D SN + K LEK R+LE +L++++ + EE + +
Sbjct: 1218 RVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLIN 1277
Query: 4660 IAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRG---LLKQIRDLENELENEKRGKS 4830
R RL+ + E R + K+ + RG +QI +L+ +LE E + K+
Sbjct: 1278 DLTAQRGRLQTES----GEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKN 1333
Query: 4831 GAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIE--------CEEAR 4986
+ + L +Q E K E +++ + EE
Sbjct: 1334 ALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELE 1393
Query: 4987 QAKEDIAALLREADRKFRAVEAE-------REQLREANEGLMQARKQXXXXXXXXXXXRA 5145
+AK+ +A L+ A+ AV A+ +++L+ E LM ++ +
Sbjct: 1394 EAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQR 1453
Query: 5146 KGGGISSEEKRRLEAKIAQXXXXXXXXQS-NCEL------------AIDKQRKAQVQLEQ 5286
I +E K++ E A+ +S EL ++ ++ L+Q
Sbjct: 1454 NFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQ 1513
Query: 5287 ITTDLSME-----------RTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMA 5433
+DL+ + + ++ E EK L+ + + +A + E E G R + ++
Sbjct: 1514 EISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASL-EHEEGKILRIQLELN 1572
Query: 5434 ALEAKV----------------------QYLEDQLNVEGQEKTAANRAARRLEKRLNDTT 5547
++++V + ++ L+ E + + A R +++E LN+
Sbjct: 1573 QVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEME 1632
Query: 5548 QQFEDEKRANEQA-------KELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREAD 5706
Q R +A + +L+ + + + R ++ +++++ + +Q E +
Sbjct: 1633 IQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIE 1692
Query: 5707 DLLDANEQLTR 5739
+L EQ R
Sbjct: 1693 ELRATLEQTER 1703
Score = 114 bits (285), Expect = 3e-23
Identities = 169/888 (19%), Positives = 349/888 (39%), Gaps = 111/888 (12%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ +E ++ +E++ ++ ++KL + E + +Q +++ E +L LQ
Sbjct: 1059 RKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQ 1118
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + +R S R ++E + + +
Sbjct: 1119 ARIEELEEEIE--AERASRAKAEKQRSDLSR--ELEEISERLEEAGGATSAQIEMNKKRE 1174
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K ++
Sbjct: 1175 AEFQKMRRDLEEATLQHEATAATLRKKHADSVAELG---EQIDNLQRVKQKLEKEKSEMK 1231
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K LE+ R L +L + K E+ + +L Q + E
Sbjct: 1232 MEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESG 1291
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ DE+ A V+ + + + I+EL+ +E E A+N + + ++
Sbjct: 1292 EFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLRE 1351
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
++ + LQ +S+ + EV TK + IQ T E +EE K K +++++ +
Sbjct: 1352 QYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQAAEEH 1409
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME-------I 3789
+E + + LEK + + E D+ ++ A+ A +DKK++ + L E
Sbjct: 1410 VEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEET 1469
Query: 3790 QANLAESDEHKRTLIDQL-------ERSRDELDHLNRVREEEEHAFANMQRRLATAXXXX 3948
A L S + R+L +L E S D+L+ L R + + +++ ++A
Sbjct: 1470 HAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRI 1529
Query: 3949 XXXXXXXXXXTR----LKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGA 4116
+ L+ A LE E+ +L + E +++ ++++I +
Sbjct: 1530 HELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEI 1589
Query: 4117 GEARR---KAEESVNQQLE----------ELRKKNLRDVEHLQKQLEESEVAKERILQSK 4257
+ +R + ES+ L+ L+KK D+ ++ QL + L++
Sbjct: 1590 DQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNY 1649
Query: 4258 KKIQQELEDSSMELENVRASHRDS-------EKRQKKFESQMAEERVAVQKALLDRDAMS 4416
+ Q L+D+ + L++ S D E+R ++++ E R +++ R
Sbjct: 1650 RNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAE 1709
Query: 4417 QELRDRETRV-------LSLLN-----EVDI------MKEHLEESDRVRRSLQQELQDSI 4542
QEL D RV SL+N E DI M++ L+E+ ++ + D+
Sbjct: 1710 QELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAA 1769
Query: 4543 SNKDDFGKNVH---ELEKAKRSLEAELNDMRVQMEELED------NLQIAE-DARLR--- 4683
++ K LE+ K+++E + D++++++E E QI + +AR+R
Sbjct: 1770 MMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELE 1829
Query: 4684 ---------------------LEVTNQALKSESDR------------------AISNKDV 4746
V ++E DR + +
Sbjct: 1830 GEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAE 1889
Query: 4747 EAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
EAEE+ L + R L++ELE + A S K+ + E+ ++
Sbjct: 1890 EAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKV 1937
>gi|157891|gb|AAA28686.1| myosin heavy chain
Length = 1962
Score = 1112 bits (2875), Expect = 0.0
Identities = 677/1916 (35%), Positives = 1071/1916 (55%), Gaps = 31/1916 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K CW+PD+ EG+L+G IK D V V L + + +D +Q+ NPPK++K EDMS
Sbjct: 35 KKSCWIPDEKEGYLLGEIKATKGDIVSVGLQGGETR-DLKKDLLQQVNPPKYEKAEDMSN 93
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LTYLN+ASVLHNL+ RYY+ LIYTYSGLFCV INPYK+ P+Y+ + ++GK+R+E+PP
Sbjct: 94 LTYLNDASVLHNLRQRYYNKLIYTYSGLFCVAINPYKRYPVYTNRCAKMYRGKRRNEVPP 153
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIFAI+D AY ML +QS+L TGESGAGKTENTKKVI Y A V +K + AA+
Sbjct: 154 HIFAISDGAYVDMLTNHVNQSMLITGESGAGKTENTKKVIAYFATVGA---SKKTDEAAK 210
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
G LE Q++Q NP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++G
Sbjct: 211 SK-----------GSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFGPTGKLAG 259
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSE-YLLEGVDNYRFLVNRGITL 972
A+IE YLLEK+RV+ Q ER +HIFYQI+ G K +L + + +Y + +T+
Sbjct: 260 ADIETYLLEKARVISQQSLERCYHIFYQIMSGSVPGVKEMCFLSDNIYDYYNVSQGKVTV 319
Query: 973 PNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRV 1152
PN+DD +EF + I+GF E + R+ +AV+ +G ++F Q + +QA +
Sbjct: 320 PNMDDGEEFQLADQAFDILGFTKQEKEDVYRITAAVMHMGGMKFKQRGREEQAEQDGEEE 379
Query: 1153 IQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLV 1332
+V L G EL K L+PRIKVG EFV + +N +Q ++ A+ K ++RLFKWLV
Sbjct: 380 GGRVSKLFGCDTAELYKNLLKPRIKVGNEFVTQGRNVQQVTNSIGALCKGVFDRLFKWLV 439
Query: 1333 TRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQE 1512
+ N++LD T ++ FIG+LDIAGFEIF+ N FEQ+CIN+TNEKLQQ FN+ MF+LEQE
Sbjct: 440 KKCNETLD-TQQKRQHFIGVLDIAGFEIFEYNGFEQLCINFTNEKLQQFFNHHMFVLEQE 498
Query: 1513 EYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NK 1689
EY+REGI+W FIDFG+DL IDLIEKPMG+L++L+EE +FPKA D++F EKL TH K
Sbjct: 499 EYKREGIDWAFIDFGMDLLACIDLIEKPMGILSILEEESMFPKATDQTFSEKLTNTHLGK 558
Query: 1690 HPKFIVPDM----RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVA 1857
F P + +HFA+ HYAG V Y+ WL KN DPLN+ VV + S + +
Sbjct: 559 SAPFQKPKPPKPGQQAAHFAIAHYAGCVSYNITGWLEKNKDPLNDTVVDQFKKSQNKLLI 618
Query: 1858 GIWKDAEFAGICAAEMNETAFGMRSRK-GMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCI 2034
I+ A+ AG E A G R +K G F TVS +KEQL LMTTLR+T PHFVRCI
Sbjct: 619 EIF--ADHAGQSGG--GEQAKGGRGKKGGGFATVSSAYKEQLNSLMTTLRSTQPHFVRCI 674
Query: 2035 IPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKN 2214
IPN K+ G ++++LV+ QL CNGVLEGIRICR+GFPNR+ + +F+ RY+IL P I
Sbjct: 675 IPNEMKQPGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKMRYQILNPAGI-VG 733
Query: 2215 FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRG 2394
D K+ ++ + +D ++YRIG +KVFFR GVL +EE RD +L ++ QA RG
Sbjct: 734 VDDPKKCGSIILESTALDPDMYRIGHTKVFFRAGVLGQMEEFRDERLGKIMSWMQAWARG 793
Query: 2395 FLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDD 2574
+LSR+ + N YL+LR W W++L+ KVKPLL V+R +DEI A+ +
Sbjct: 794 YLSRKGFKKLQEQRVALKVVQRNLRKYLQLRTWPWYKLWQKVKPLLNVSRIEDEI-ARLE 852
Query: 2575 ELRATKERLLKMEHDFRENEKKLD-QVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQ 2751
E E L E R+ + L+ +++ E+ + + L E + + +L +
Sbjct: 853 EKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQDYQERNAKLTAQKN 912
Query: 2752 ELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQ 2931
+LE + D+++RL+ ++K + + DK D
Sbjct: 913 DLENQLRDIQERLTQEEDARNQLFQQKKKADQEISGLKKDIEDLELNVQKAEQDKATKDH 972
Query: 2932 XXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHE 3111
+ + +L E++ H K K +LE L E
Sbjct: 973 QIRNLNDEIAHQDELINKLNKEKKMQGETNQKTGEELQAAEDKINHLNKVKAKLEQTLDE 1032
Query: 3112 LEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTR 3291
LE L RE++ + ++E+ KRK+ +L+ +++ +A+ +EL + ++D+EL +
Sbjct: 1033 LEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVADLERNKKELEQTIQRKDKELSSITAK 1092
Query: 3292 YDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDK 3471
++E V Q+Q++++Q I+EL E++E ER AR KAE R ++ +LE++ G+ L++
Sbjct: 1093 LEDEQVVVLKHQRQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEEL-GERLEE 1151
Query: 3472 VDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKK 3648
AT Q +L +++ E++ +R +E+ E + + K + V E+ +Q++Q K
Sbjct: 1152 AGGATSAQIELNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNK 1211
Query: 3649 QRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRT 3828
+++ E + E L +A +K K + L E+Q+ L DE RT
Sbjct: 1212 LKAKAEHDRQTCHNELNQTRTACDQLGRDKAAQEKIAKQLQHTLNEVQSKL---DETNRT 1268
Query: 3829 LIDQLERSRDEL----DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIA 3996
L D + S+ +L L R EE E + + + + +R +
Sbjct: 1269 LND-FDASKKKLSIENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERAT 1327
Query: 3997 NINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHAARQGAGEARRKAEE---SVNQQLE 4164
+ + R LE + + L ++ +EEAEG +A L++++ A A R K E + +++LE
Sbjct: 1328 LLGKFRNLEHDLDNLREQVEEEAEG-KADLQRQLSKANAEAQVWRSKYESDGVARSEELE 1386
Query: 4165 ELRKKNLRDVEHLQKQLEESEVAKERILQ-------SKKKIQQELEDSSMELENVRASHR 4323
E ++K LQ +L E+E E + Q +K+++ E+ED +E++ A
Sbjct: 1387 EAKRK-------LQARLAEAEETIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIAN 1439
Query: 4324 DSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDR 4503
+EK+QK F+ + E ++ V + DA +E R+ T + L + +E LE R
Sbjct: 1440 AAEKKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRR 1499
Query: 4504 VRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLR 4683
++L E++D + + G+N+HE+EKA++ LEAE ++++ +EE E L+ E+ LR
Sbjct: 1500 ENKNLADEVKDLLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLR 1559
Query: 4684 LEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIEN 4863
++ ++ E DR I K+ E E R+ + + ++ LE E +GK+ A+ +KK+E
Sbjct: 1560 AQLELSQVRQEIDRRIQEKEEEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEA 1619
Query: 4864 QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRA 5043
I ELE L+ AN+ E + Q EE ++A++D L ++R+ A
Sbjct: 1620 DINELEIALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANA 1679
Query: 5044 VEAEREQ----LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXX 5211
++ E E+ L +A+ G QA ++ A+ IS+ KR+LE+++
Sbjct: 1680 LQNELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISA-AKRKLESELQTLHS 1738
Query: 5212 XXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITE 5391
+ + + +K +KA V ++ +L E+ Q E +++LE+ ++ + ++ E
Sbjct: 1739 DLDELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDE 1798
Query: 5392 LESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKR 5571
E+ A + + LE +V+ LE++L+ E + A + R+ E+R+ + + Q E++++
Sbjct: 1799 AEANALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRK 1858
Query: 5572 ANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQR---EADDLLDANEQ 5730
+E+ ++L++K K + +RQ++EAE+ + K R Q+ EA++ D EQ
Sbjct: 1859 NHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQ 1914
Score = 151 bits (382), Expect = 2e-34
Identities = 178/950 (18%), Positives = 386/950 (39%), Gaps = 62/950 (6%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDE 3267
RLE + + E+ E + + ELE KLLAE D L+ + G +++
Sbjct: 850 RLEEKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQD---------- 899
Query: 3268 ELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEK 3447
Y E +A +T Q D++ + +++E + E +ARN+ +++ ++
Sbjct: 900 --------YQERNAKLTA---QKNDLENQLRDIQERLTQEEDARNQLFQQKKKADQEISG 948
Query: 3448 VKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+K D+ D + + KD ++ I Q + K+ ++K ++ +
Sbjct: 949 LKKDIEDLELNVQKAEQDKATKDHQIRNLNDEIAH-QDELINKLNKEKKMQGETNQKTGE 1007
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAE 3807
+++ + + + L K + + +Q ++ + + R D++K ++ E L Q +A+
Sbjct: 1008 ELQAAEDKINHLNKVKAKLEQTLDELEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVAD 1067
Query: 3808 SDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL 3987
+ +K+ L ++R EL + E+E+ QR++
Sbjct: 1068 LERNKKELEQTIQRKDKELSSITAKLEDEQVVVLKHQRQIKELQA--------------- 1112
Query: 3988 KIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEE 4167
R +LE+E A + +AE RA L +E+ + GE +A + + Q+E
Sbjct: 1113 ------RIEELEEEVEAERQARAKAEKQRADLAREL----EELGERLEEAGGATSAQIE- 1161
Query: 4168 LRKKNLRDVEHLQKQLEESEVAKERILQS-KKKIQQELEDSSMELENVRASHRDSEKRQK 4344
L KK ++ L++ LEE+ + E L + +KK + + + +++ + +E ++
Sbjct: 1162 LNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNKLKAKAEHDRQ 1221
Query: 4345 KFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQ 4524
+++ + R A + D+ A + + + + + +++D L + D ++ L
Sbjct: 1222 TCHNELNQTRTACDQLGRDKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSI 1281
Query: 4525 ELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE--------------LE---DN 4653
E D + ++ V +L K K SL +L D + +E LE DN
Sbjct: 1282 ENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERATLLGKFRNLEHDLDN 1341
Query: 4654 L--QIAEDARLRLEVTNQALKSESDRAISNKDVEA---------EEKRRGLLKQIRDLEN 4800
L Q+ E+A + ++ Q K+ ++ + E+ EE +R L ++ + E
Sbjct: 1342 LREQVEEEAEGKADLQRQLSKANAEAQVWRSKYESDGVARSEELEEAKRKLQARLAEAEE 1401
Query: 4801 ELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEE 4980
+E+ + G ++++ ++ +L+ +++ AN + E++++ ++
Sbjct: 1402 TIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIANAAEKKQKAFDKIIGEWKLKVDD 1461
Query: 4981 ARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGG-G 5157
+ R + ++ E+ +E E + + K +GG
Sbjct: 1462 LAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGRN 1521
Query: 5158 ISSEEK--RRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKT 5331
I EK +RLEA+ + ++ E +K +AQ++L Q+ ++ +R + +K
Sbjct: 1522 IHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEI--DRRIQEKE 1579
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRARA--QMAALEAKVQYLEDQLNVEGQEKTAAN 5505
E + + + R + LE+ A+ +A A LEA + LE L+ + A
Sbjct: 1580 EEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQ 1639
Query: 5506 RAARRLEKRLNDTTQQFEDEKR----------------------------ANEQAKELLE 5601
+ +R +++L D E+E+R EQA
Sbjct: 1640 KNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRR 1699
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
++ + + QL+E + + R ++ E L ++L E N
Sbjct: 1700 QAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDELLNEAKN 1749
Score = 82.4 bits (202), Expect = 1e-13
Identities = 82/418 (19%), Positives = 183/418 (43%), Gaps = 25/418 (5%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L +Q+ E ++++ + + LE K +L A LE+++ L ++ KV +L + +E
Sbjct: 1511 LLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQE 1570
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ ++ +EE N ++ Q +D ++ +E E + +A ++++ A + ++
Sbjct: 1571 IDRRIQEKEEEFENTR------KNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINEL 1624
Query: 3451 KGDVLDKVDEATM-LQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+ LD ++A Q + R +++ + A+E+ Q + EQ R+ L +
Sbjct: 1625 E-IALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDA-REQLGISERRANALQN 1682
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL-- 3801
++E+ + Q ++ + QA+QE AD +++ + A A I ++ E+ L + ++L
Sbjct: 1683 ELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDE 1742
Query: 3802 ----AESDEHKRT--------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
A++ E K L D+L +D ++R+ E +Q RL A
Sbjct: 1743 LLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAEAN 1802
Query: 3946 XXXXXXXXXXXTRLKIANIN------RARQLEDEKNALLDEKEEAE-GLRAHLEKEIHAA 4104
++ + + R + +KN E+ E ++ +++ H
Sbjct: 1803 ALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRKNHER 1862
Query: 4105 RQGAGEARRKAEESVNQQLEELRK---KNLRDVEHLQKQLEESEVAKERILQSKKKIQ 4269
Q + ++ ++ +Q+EE + NL Q++LEE+E + Q+ K +
Sbjct: 1863 MQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQAISKFR 1920
>gi|38347761|dbj|BAD01606.1| myosin heavy chain [Lethenteron
japonicum]
Length = 1934
Score = 1110 bits (2872), Expect = 0.0
Identities = 649/1913 (33%), Positives = 1073/1913 (55%), Gaps = 23/1913 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K C+V D F+ +IK +V V+ + + VT+ D V + NPPKFDKIEDM
Sbjct: 32 KKNCFVDDPKIEFVKATIKSSEGGKVTVD-TENGQTVTVREDQVHQMNPPKFDKIEDMVM 90
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LT+LNE SVL NLK+RY + +IYTYSGLFCV +NPYK LP+Y ++ ++GKKR E PP
Sbjct: 91 LTFLNEPSVLFNLKERYAAWMIYTYSGLFCVTVNPYKMLPVYDPIVVAGYRGKKRQEAPP 150
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIF+I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A +L +A+
Sbjct: 151 HIFSISDNAYQFMLSDRENQSILITGESGAGKTVNTKRVIQYFATIA------ALGDSAK 204
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
+ Q+ ++ G LE Q+++ANP++EAFGN+KTV+NDNSSRFGKFIRI+F +G ++
Sbjct: 205 KK--QEGKIK---GTLEDQIVEANPLMEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLAS 259
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYL-----LEGVDNYRFLVNR 960
A+IE YLLEKSRV Q ER++HIF+QIL +++K E L +Y F+
Sbjct: 260 ADIETYLLEKSRVTFQLPTERNYHIFFQIL----SQQKPELLDMLLVTTNPYDYPFISQG 315
Query: 961 GITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQ 1140
IT+ ++DD +E +T +++ I+GF ++E SI ++ +++ GN++F Q+++ +QA
Sbjct: 316 EITVSSIDDKEELMATDSAIEILGFTNEEKMSIYKLTGSIMHYGNMKFKQKQREEQAEPD 375
Query: 1141 DDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLF 1320
K C L+G+ +L KA PR+KVG E+V K Q Q + A+ KA +ERLF
Sbjct: 376 GSEDADKACFLMGINSADLLKALCLPRVKVGNEYVTKGQTVPQVYNNIGALGKACFERLF 435
Query: 1321 KWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFI 1500
W+V RIN+SLD T + FIG+LDIAGFEIFD N+FEQ+CIN+TNEKLQQ FN+ MF+
Sbjct: 436 LWMVIRINQSLD-TKQARQHFIGVLDIAGFEIFDFNTFEQLCINFTNEKLQQFFNHHMFV 494
Query: 1501 LEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKT 1680
LEQEEY++EGI+W FIDFG+DLQ IDLIEKP+G++++L+E+C+FPKAND++F EKL
Sbjct: 495 LEQEEYKKEGIDWVFIDFGMDLQACIDLIEKPLGIMSILEEQCMFPKANDQTFKEKLYDQ 554
Query: 1681 HNKHPKFIVPDMRSK----SHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDP 1848
H KF SK +HF++ HYAG VDY+ WL KN DPLN++VV + Q ++
Sbjct: 555 HLGKNKFFQKPKPSKGKHEAHFSLGHYAGNVDYNIAGWLEKNKDPLNDSVVQVYQKASLK 614
Query: 1849 FVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVR 2028
+ ++ A FAG A+ + A + + F+TVS LH+E L+KLMT L+ T PHFVR
Sbjct: 615 VLGALF--ATFAG---ADADSGAKKGKKKGSSFQTVSALHRENLSKLMTNLKTTHPHFVR 669
Query: 2029 CIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIP 2208
C+IPN K G +++NLV+ QLRCNGVLEGIRICR+GFPNR+ + +F+ RY +L P+ +P
Sbjct: 670 CLIPNETKTPGTMDNNLVMHQLRCNGVLEGIRICRKGFPNRIVYGDFKQRYRVLNPNAMP 729
Query: 2209 K-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQ 2385
+ F+D K++ K++ +L++D Y+ G +KVFFR G+L LEE RD +L+ L+ QA
Sbjct: 730 EGQFVDSKKACEKLMASLELDETQYKFGHTKVFFRAGLLGTLEEMRDDRLSLLLTRTQAL 789
Query: 2386 CRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRA 2565
RG+LSR + N A++ ++NW W L+ K+KPLL+ ++ E+
Sbjct: 790 GRGYLSRVEFKKMLERRESLIVIQYNIRAFMGVKNWPWMNLYFKIKPLLKSAESEKEMAN 849
Query: 2566 KDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTR 2745
+E TKE L K E +E E+K+ V+ E+ + Q+Q ++ + ++ +L
Sbjct: 850 MKEEFIKTKEALEKSEARRKELEEKMISVVQEKNDLLMQVQSGEDSINDSEERCDQLIKA 909
Query: 2746 NQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNV 2925
+LE + +M++R+ +RK + + +K
Sbjct: 910 KIQLESKLKEMQERIEEEEEMNSELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHAT 969
Query: 2926 DQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQL 3105
+ + L E++ KAK +LE Q+
Sbjct: 970 ENKVKNLTEEMAVLDENVSKLTKEKKALQEAHQQTLDDLQAEEDKVNSLTKAKAKLEQQV 1029
Query: 3106 HELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQL 3285
+LE L +E++ + ++E+ KRKL + + +++ + + ++++ + K+D E+
Sbjct: 1030 DDLEGSLEQEKKVRMDIERTKRKLEGDFKMAQESIMDLENDKQQIDEKTKKKDFEISQLN 1089
Query: 3286 TRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVL 3465
++ ++E A +QK+++++Q I+EL E++E ER AR K E R ++ +LE++ + L
Sbjct: 1090 SKIEDELALSAQLQKKIKELQARIEELEEEIEAERAARAKVEKQRSDLSRELEEI-SERL 1148
Query: 3466 DKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQH 3642
++ AT Q M++K E E +R +E+ E + K + V EL +QI+
Sbjct: 1149 EEAGGATSAQIEMNKKREAEFQKLRRDLEESTLQHEATAAALRKKQADSVAELGEQIDNL 1208
Query: 3643 KKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHK 3822
++ + +LEK++++ E D++ + + S+ +++K + E L E++ + DE+
Sbjct: 1209 QRVKQKLEKEKSEFKMEVDDLSSNMEQITKSKVNLEKLSRSLEDQLSELK---TKDDENI 1265
Query: 3823 RTLID---QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKI 3993
RT+ D Q R + E L R EE+E + R + + K
Sbjct: 1266 RTINDITAQRARLQTESGELTRKLEEKEVLVVQLSRGKQSYTQQVEDLKRQLEEEVKAKN 1325
Query: 3994 ANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELR 4173
A + + + + L ++ +E + + L++ + A + R K E Q+ EEL
Sbjct: 1326 ALAHAVQSARHDCDLLREQFDEEQEAKGELQRAMSKANAEVAQWRTKYETDAIQRTEELE 1385
Query: 4174 KKNLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQK 4344
+ LQ E+ E A + + ++K+++Q E+ED +++E ++ +K+QK
Sbjct: 1386 DAKKKLAARLQDAEEQVEAANSKCASLEKTKQRLQGEVEDLMIDVERAHSAAAALDKKQK 1445
Query: 4345 KFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQ 4524
F+ ++E + +++ + +A +E R T + L N + +HLE R ++LQ+
Sbjct: 1446 AFDKVLSEWKQKFEESQAELEAAQKESRSLGTELFKLKNAYEETLDHLETFKRENKNLQE 1505
Query: 4525 ELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQA 4704
E+ D + K++HELEK ++++E E +D++ +EE E +L+ E LR+++
Sbjct: 1506 EISDLTEQLGESSKSLHELEKNRKAIEQEKSDIQAALEEAEASLEHEEGKILRVQLELNQ 1565
Query: 4705 LKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQ 4884
+K+E DR I+ KD E ++ +RG + + ++ L++E + ++ A+ +KK+E + E+E
Sbjct: 1566 VKAEVDRKIAEKDEEIDQIKRGFQRTVESMQATLDSETKSRNEALRLKKKMEGDLNEMEI 1625
Query: 4885 QLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQ 5064
QL ANR E + Q+ ++A +A ED +R+ + AE E+
Sbjct: 1626 QLNHANRQAAESQKHLRNVQGQIKDLQVHLDDALRANEDHKEQAAMLERRNNLLVAEVEE 1685
Query: 5065 LREANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSN 5235
+R A E +ARK Q KR+LE ++Q
Sbjct: 1686 MRSALEQTEKARKLAEQELLGATERVQLLHSQNTSLINTKRKLEGDLSQLQSEVEESIQE 1745
Query: 5236 CELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSR 5415
A +K +KA + +L E+ + E K+++E++ +D + ++ E E A
Sbjct: 1746 SRNADEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQHRLDEAEQIAMKG 1805
Query: 5416 ARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKEL 5595
+ Q+ LE +V+ LE +L+ E + + +R+ E+R+ + + Q E++++ N + ++L
Sbjct: 1806 GKKQLQKLETRVRELESELDAEQRRTAETIKGSRKYERRIKELSYQTEEDRKNNLRLQDL 1865
Query: 5596 LEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQ---READDLLDANEQLTREL 5745
++K LK + +RQ +E+E++ + +K+R +Q EAD+ D E +L
Sbjct: 1866 VDKLQLKVKAYKRQSEESEEQANTNLSKYRKLQHELEEADERADIAESQVNKL 1918
>gi|20455497|sp|P05661|MYSA_DROME Myosin heavy chain, muscle
Length = 1962
Score = 1110 bits (2871), Expect = 0.0
Identities = 674/1916 (35%), Positives = 1072/1916 (55%), Gaps = 31/1916 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K CW+PD+ EG+L+G IK D V V L + I + V+K NPPKF+KIEDM++
Sbjct: 35 KKSCWIPDEKEGYLLGEIKATKGDIVSVGLQGGEVR-DIKSEKVEKVNPPKFEKIEDMAD 93
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
+T LN VLHNL+ RYY+ LIYTYSGLFCV INPYK+ P+Y+ + ++GK+R+E+PP
Sbjct: 94 MTVLNTPCVLHNLRQRYYAKLIYTYSGLFCVAINPYKRYPVYTNRCAKMYRGKRRNEVPP 153
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIFAI+D AY ML +QS+L TGESGAGKTENTKKVI Y A V +K + AA+
Sbjct: 154 HIFAISDGAYVDMLTNHVNQSMLITGESGAGKTENTKKVIAYFATVGA---SKKTDEAAK 210
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
G LE Q++Q NP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++G
Sbjct: 211 SK-----------GSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFGPTGKLAG 259
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLL-EGVDNYRFLVNRGITL 972
A+IE YLLEK+RV+ Q ER +HIFYQI+ G K LL + + +Y + +T+
Sbjct: 260 ADIETYLLEKARVISQQSLERCYHIFYQIMSGSVPGVKDICLLTDNIYDYHIVSQGKVTV 319
Query: 973 PNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRV 1152
++DD +EF T + I+GF E + R+ +AV+ +G ++F Q + +QA +
Sbjct: 320 ASIDDAEEFSLTDQAFDILGFTKQEKEDVYRITAAVMHMGGMKFKQRGREEQAEQDGEEE 379
Query: 1153 IQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLV 1332
+V L G EL K L+PRIKVG EFV + +N +Q ++ A+ K ++RLFKWLV
Sbjct: 380 GGRVSKLFGCDTAELYKNLLKPRIKVGNEFVTQGRNVQQVTNSIGALCKGVFDRLFKWLV 439
Query: 1333 TRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQE 1512
+ N++LD T ++ FIG+LDIAGFEIF+ N FEQ+CIN+TNEKLQQ FN+ MF++EQE
Sbjct: 440 KKCNETLD-TQQKRQHFIGVLDIAGFEIFEYNGFEQLCINFTNEKLQQFFNHIMFVMEQE 498
Query: 1513 EYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NK 1689
EY++EGI WDFIDFG+DL IDLIEKPMG+L++L+EE +FPKA D++F EKL TH K
Sbjct: 499 EYKKEGINWDFIDFGMDLLACIDLIEKPMGILSILEEESMFPKATDQTFSEKLTNTHLGK 558
Query: 1690 HPKFIVPDM----RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVA 1857
F P + +HFA+ HYAG V Y+ WL KN DPLN+ VV + S + +
Sbjct: 559 SAPFQKPKPPKPGQQAAHFAIAHYAGCVSYNITGWLEKNKDPLNDTVVDQFKKSQNKLLI 618
Query: 1858 GIWKDAEFAGICAAEMNETAFGMRSRK-GMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCI 2034
I+ A+ AG E A G R +K G F TVS +KEQL LMTTLR+T PHFVRCI
Sbjct: 619 EIF--ADHAGQSGG--GEQAKGGRGKKGGGFATVSSAYKEQLNSLMTTLRSTQPHFVRCI 674
Query: 2035 IPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKN 2214
IPN K+ G ++++LV+ QL CNGVLEGIRICR+GFPNR+ + +F+ RY+IL P I K+
Sbjct: 675 IPNEMKQPGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKMRYQILNPRGI-KD 733
Query: 2215 FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRG 2394
K++ + +I + +++ +LYR+G +KVFFR GVL +EE RD +L ++ QA RG
Sbjct: 734 LDCPKKASKVLIESTELNEDLYRLGHTKVFFRAGVLGQMEEFRDERLGKIMSWMQAWARG 793
Query: 2395 FLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDD 2574
+LSR+ + N YL+LR W W++L+ KVKPLL V+R +DEI A+ +
Sbjct: 794 YLSRKGFKKLQEQRVALKVVQRNLRKYLQLRTWPWYKLWQKVKPLLNVSRIEDEI-ARLE 852
Query: 2575 ELRATKERLLKMEHDFRENEKKLD-QVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQ 2751
E E L E R+ + L+ +++ E+ + + L E + + +L +
Sbjct: 853 EKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQDYQERNAKLTAQKN 912
Query: 2752 ELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQ 2931
+LE + D+++RL+ ++K + + DK D
Sbjct: 913 DLENQLRDIQERLTQEEDARNQLFQQKKKADQEISGLKKDIEDLELNVQKAEQDKATKDH 972
Query: 2932 XXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHE 3111
+ + +L E++ H K K +LE L E
Sbjct: 973 QIRNLNDEIAHQDELINKLNKEKKMQGETNQKTGEELQAAEDKINHLNKVKAKLEQTLDE 1032
Query: 3112 LEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTR 3291
LE L RE++ + ++E+ KRK+ +L+ +++ +A+ +EL + ++D+EL +
Sbjct: 1033 LEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVADLERNKKELEQTIQRKDKELSSITAK 1092
Query: 3292 YDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDK 3471
++E V Q+Q++++Q I+EL E++E ER AR KAE R ++ +LE++ G+ L++
Sbjct: 1093 LEDEQVVVLKHQRQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEEL-GERLEE 1151
Query: 3472 VDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKK 3648
AT Q +L +++ E++ +R +E+ E + + K + V E+ +Q++Q K
Sbjct: 1152 AGGATSAQIELNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNK 1211
Query: 3649 QRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRT 3828
+++ E + E L +A +K K + L E+Q+ L DE RT
Sbjct: 1212 LKAKAEHDRQTCHNELNQTRTACDQLGRDKAAQEKIAKQLQHTLNEVQSKL---DETNRT 1268
Query: 3829 LIDQLERSRDEL----DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIA 3996
L D + S+ +L L R EE E + + + + +R +
Sbjct: 1269 LND-FDASKKKLSIENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERAT 1327
Query: 3997 NINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHAARQGAGEARRKAEE---SVNQQLE 4164
+ + R LE + + L ++ +EEAEG +A L++++ A A R K E + +++LE
Sbjct: 1328 LLGKFRNLEHDLDNLREQVEEEAEG-KADLQRQLSKANAEAQVWRSKYESDGVARSEELE 1386
Query: 4165 ELRKKNLRDVEHLQKQLEESEVAKERILQ-------SKKKIQQELEDSSMELENVRASHR 4323
E ++K LQ +L E+E E + Q +K+++ E+ED +E++ A
Sbjct: 1387 EAKRK-------LQARLAEAEETIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIAN 1439
Query: 4324 DSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDR 4503
+EK+QK F+ + E ++ V + DA +E R+ T + L + +E LE R
Sbjct: 1440 AAEKKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRR 1499
Query: 4504 VRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLR 4683
++L E++D + + G+N+HE+EKA++ LEAE ++++ +EE E L+ E+ LR
Sbjct: 1500 ENKNLADEVKDLLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLR 1559
Query: 4684 LEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIEN 4863
++ ++ E DR I K+ E E R+ + + ++ LE E +GK+ A+ +KK+E
Sbjct: 1560 AQLELSQVRQEIDRRIQEKEEEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEA 1619
Query: 4864 QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRA 5043
I ELE L+ AN+ E + Q EE ++A++D L ++R+ A
Sbjct: 1620 DINELEIALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANA 1679
Query: 5044 VEAEREQ----LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXX 5211
++ E E+ L +A+ G QA ++ A+ IS+ KR+LE+++
Sbjct: 1680 LQNELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISA-AKRKLESELQTLHS 1738
Query: 5212 XXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITE 5391
+ + + +K +KA V ++ +L E+ Q E +++LE+ ++ + ++ E
Sbjct: 1739 DLDELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDE 1798
Query: 5392 LESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKR 5571
E+ A + + LE +V+ LE++L+ E + A + R+ E+R+ + + Q E++++
Sbjct: 1799 AEANALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRK 1858
Query: 5572 ANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQR---EADDLLDANEQ 5730
+E+ ++L++K K + +RQ++EAE+ + K R Q+ EA++ D EQ
Sbjct: 1859 NHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQ 1914
Score = 151 bits (382), Expect = 2e-34
Identities = 178/950 (18%), Positives = 386/950 (39%), Gaps = 62/950 (6%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDE 3267
RLE + + E+ E + + ELE KLLAE D L+ + G +++
Sbjct: 850 RLEEKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQD---------- 899
Query: 3268 ELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEK 3447
Y E +A +T Q D++ + +++E + E +ARN+ +++ ++
Sbjct: 900 --------YQERNAKLTA---QKNDLENQLRDIQERLTQEEDARNQLFQQKKKADQEISG 948
Query: 3448 VKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+K D+ D + + KD ++ I Q + K+ ++K ++ +
Sbjct: 949 LKKDIEDLELNVQKAEQDKATKDHQIRNLNDEIAH-QDELINKLNKEKKMQGETNQKTGE 1007
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAE 3807
+++ + + + L K + + +Q ++ + + R D++K ++ E L Q +A+
Sbjct: 1008 ELQAAEDKINHLNKVKAKLEQTLDELEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVAD 1067
Query: 3808 SDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL 3987
+ +K+ L ++R EL + E+E+ QR++
Sbjct: 1068 LERNKKELEQTIQRKDKELSSITAKLEDEQVVVLKHQRQIKELQA--------------- 1112
Query: 3988 KIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEE 4167
R +LE+E A + +AE RA L +E+ + GE +A + + Q+E
Sbjct: 1113 ------RIEELEEEVEAERQARAKAEKQRADLAREL----EELGERLEEAGGATSAQIE- 1161
Query: 4168 LRKKNLRDVEHLQKQLEESEVAKERILQS-KKKIQQELEDSSMELENVRASHRDSEKRQK 4344
L KK ++ L++ LEE+ + E L + +KK + + + +++ + +E ++
Sbjct: 1162 LNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNKLKAKAEHDRQ 1221
Query: 4345 KFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQ 4524
+++ + R A + D+ A + + + + + +++D L + D ++ L
Sbjct: 1222 TCHNELNQTRTACDQLGRDKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSI 1281
Query: 4525 ELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE--------------LE---DN 4653
E D + ++ V +L K K SL +L D + +E LE DN
Sbjct: 1282 ENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERATLLGKFRNLEHDLDN 1341
Query: 4654 L--QIAEDARLRLEVTNQALKSESDRAISNKDVEA---------EEKRRGLLKQIRDLEN 4800
L Q+ E+A + ++ Q K+ ++ + E+ EE +R L ++ + E
Sbjct: 1342 LREQVEEEAEGKADLQRQLSKANAEAQVWRSKYESDGVARSEELEEAKRKLQARLAEAEE 1401
Query: 4801 ELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEE 4980
+E+ + G ++++ ++ +L+ +++ AN + E++++ ++
Sbjct: 1402 TIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIANAAEKKQKAFDKIIGEWKLKVDD 1461
Query: 4981 ARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGG-G 5157
+ R + ++ E+ +E E + + K +GG
Sbjct: 1462 LAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGRN 1521
Query: 5158 ISSEEK--RRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKT 5331
I EK +RLEA+ + ++ E +K +AQ++L Q+ ++ +R + +K
Sbjct: 1522 IHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEI--DRRIQEKE 1579
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRARA--QMAALEAKVQYLEDQLNVEGQEKTAAN 5505
E + + + R + LE+ A+ +A A LEA + LE L+ + A
Sbjct: 1580 EEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQ 1639
Query: 5506 RAARRLEKRLNDTTQQFEDEKR----------------------------ANEQAKELLE 5601
+ +R +++L D E+E+R EQA
Sbjct: 1640 KNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRR 1699
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
++ + + QL+E + + R ++ E L ++L E N
Sbjct: 1700 QAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDELLNEAKN 1749
Score = 82.4 bits (202), Expect = 1e-13
Identities = 82/418 (19%), Positives = 183/418 (43%), Gaps = 25/418 (5%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L +Q+ E ++++ + + LE K +L A LE+++ L ++ KV +L + +E
Sbjct: 1511 LLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQE 1570
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ ++ +EE N ++ Q +D ++ +E E + +A ++++ A + ++
Sbjct: 1571 IDRRIQEKEEEFENTR------KNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINEL 1624
Query: 3451 KGDVLDKVDEATM-LQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+ LD ++A Q + R +++ + A+E+ Q + EQ R+ L +
Sbjct: 1625 E-IALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDA-REQLGISERRANALQN 1682
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL-- 3801
++E+ + Q ++ + QA+QE AD +++ + A A I ++ E+ L + ++L
Sbjct: 1683 ELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDE 1742
Query: 3802 ----AESDEHKRT--------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
A++ E K L D+L +D ++R+ E +Q RL A
Sbjct: 1743 LLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAEAN 1802
Query: 3946 XXXXXXXXXXXTRLKIANIN------RARQLEDEKNALLDEKEEAE-GLRAHLEKEIHAA 4104
++ + + R + +KN E+ E ++ +++ H
Sbjct: 1803 ALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRKNHER 1862
Query: 4105 RQGAGEARRKAEESVNQQLEELRK---KNLRDVEHLQKQLEESEVAKERILQSKKKIQ 4269
Q + ++ ++ +Q+EE + NL Q++LEE+E + Q+ K +
Sbjct: 1863 MQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQAISKFR 1920
>gi|13431707|sp|Q28641|MYH4_RABIT Myosin heavy chain, skeletal muscle,
juvenile
gi|11276952|pir||A59293 skeletal myosin heavy chain - domestic rabbit
gi|940233|gb|AAA74199.1| myosin heavy chain
Length = 1938
Score = 1110 bits (2871), Expect = 0.0
Identities = 653/1892 (34%), Positives = 1053/1892 (55%), Gaps = 18/1892 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V D E F+ +++ +V + + VT+ D V NPPK+DKIEDM+ +T+L
Sbjct: 39 FVADPKESFVKATVQSREGGKVTAK-TEAGATVTVKEDQVFPMNPPKYDKIEDMAMMTHL 97
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+ Y + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 98 HEPAVLYNLKEXYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFS 157
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A T +K A +
Sbjct: 158 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIA-VTGDKKKEEATSGKMQ 216
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
G LE Q++ ANP+LEAF N+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 217 ---------GTLEDQIISANPLLEAFANAKTVRNDNSSRFGKFIRIHFGTTGKLASADIE 267
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPNV 981
YLLEKSRV Q + ERS+HIFYQI+ + E LL + +Y F+ IT+P++
Sbjct: 268 TYLLEKSRVTFQLKAERSYHIFYQIMSN-KKPDLIEMLLITTNPYDYAFVSQGEITVPSI 326
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
DD +E +T +++ I+GF DE SI ++ AV+ GN++F Q+++ +QA V K
Sbjct: 327 DDQEELMATDSAIDILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADK 386
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L L +L KA PR+KVG E+V K Q +Q AV A+AKA YE++F W+VTRI
Sbjct: 387 AAYLQSLNSXDLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRI 446
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 447 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH----NK 1689
+EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL + H N
Sbjct: 506 KEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNN 565
Query: 1690 HPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
K + ++HF++VHYAG VDY+ WL KN DPLNE VVGL Q S +A +
Sbjct: 566 FQKPKPAKRKVEAHFSLVHYAGTVDYNITGWLDKNKDPLNETVVGLYQKSAMKTLAFL-- 623
Query: 1870 DAEFAGICAAEMNETAFGMRSRKG-MFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNH 2046
F G AAE +KG F+TVS L +E L KLMT LR SPHFVR IIPN
Sbjct: 624 ---FTGTAAAEAEGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRTHSPHFVRSIIPNE 680
Query: 2047 EKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFID 2223
K G + LVL QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L IP+ FID
Sbjct: 681 TKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFID 740
Query: 2224 GKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLS 2403
K++ K++ ++D+D Y+ G +KVFF+ G+L LEE RD KL LI QA CRGFL+
Sbjct: 741 SKKASEKLLGSIDVDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQAMCRGFLA 800
Query: 2404 RRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELR 2583
R Y N A++ +++W W +L+ K+KPLL+ T+ E+ +E
Sbjct: 801 RVEYKKMVERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFE 860
Query: 2584 ATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEY 2763
TKE L K E +E E+K+ ++ E+ +Q Q+Q E+++ A+ ++ +L +LE
Sbjct: 861 KTKESLAKAEAKEKELEEKMVALMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEA 920
Query: 2764 IVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXX 2943
+ ++ +R +RK + + +K +
Sbjct: 921 KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 980
Query: 2944 XXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQD 3123
+ L E++ KAK +LE Q+ +LE
Sbjct: 981 LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGS 1040
Query: 3124 LNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEE 3303
L +E++ + +LE+ KRKL +L+ +++ + ++L+ +L K++ E+ + ++ ++E
Sbjct: 1041 LEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDE 1100
Query: 3304 SANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEA 3483
A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L++ A
Sbjct: 1101 QALAMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEI-SERLEEAGGA 1159
Query: 3484 TMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQ 3660
T Q M++K E E +R +E+ E + K + V EL +QI+ ++ + +
Sbjct: 1160 TSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQK 1219
Query: 3661 LEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLID- 3837
LEK++++ E D+A + + ++ +++K + E + E++ + +EH+R + D
Sbjct: 1220 LEKEKSELKMEIDDLASNMETVSKAKGNLEKMCRTLEDQVSELK---TKEEEHQRLINDL 1276
Query: 3838 --QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRA 4011
Q R + E +R +E++ + + R + K A +
Sbjct: 1277 SAQRARLQTESGEFSRQLDEKDSLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHAL 1336
Query: 4012 RQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRD 4191
+ + + L ++ EE + +A L++ + A + R K E Q+ EEL + +
Sbjct: 1337 QSARHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 1396
Query: 4192 VEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQM 4362
+ LQ E E + + ++K+++Q E+ED +++E A+ +K+Q+ F+ +
Sbjct: 1397 AQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKIL 1456
Query: 4363 AEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSI 4542
AE + ++ + +A +E R T V + N + + LE R ++LQQE+ D
Sbjct: 1457 AEWKHKYEETHAELEASQKESRSLSTEVFKVKNAYEESLDQLETLKRENKNLQQEISDLT 1516
Query: 4543 SNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESD 4722
+ GK +HELEK K+ +E E ++++ +EE E +L+ E LR+++ +KSE D
Sbjct: 1517 EQIAEGGKRIHELEKVKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEID 1576
Query: 4723 RAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVAN 4902
R I+ KD E ++ +R ++ + +++ L+ E R ++ A+ +KK+E + E+E QL AN
Sbjct: 1577 RKIAEKDEEIDQLKRNHIRVVESMQSTLDAEIRSRNDAIRIKKKMEGDLNEMEIQLNHAN 1636
Query: 4903 RLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANE 5082
R+ E + Q+ ++A + +ED+ L +R+ ++AE E+LR E
Sbjct: 1637 RMAAEALRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLE 1696
Query: 5083 GLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAID 5253
++RK Q K++LE I+Q A +
Sbjct: 1697 QTERSRKVAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEE 1756
Query: 5254 KQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMA 5433
K +KA + +L E+ + E K+++E++ +D + ++ E E A + Q+
Sbjct: 1757 KAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQ 1816
Query: 5434 ALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNL 5613
LEA+V+ LE ++ E + A + R+ E+R+ + T Q E++++ + ++L++K
Sbjct: 1817 KLEARVRELEAEVESEQKRNVEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQA 1876
Query: 5614 KNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
K ++ +RQ +EAE++ + +K R +Q E ++
Sbjct: 1877 KVKSYKRQAEEAEEQCNINLSKFRKLQHELEE 1908
Score = 157 bits (397), Expect = 3e-36
Identities = 189/923 (20%), Positives = 384/923 (41%), Gaps = 37/923 (4%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + + ++ L + + ELE+ L+ E D + + A+ + EE +
Sbjct: 850 KEMANMKEEFEKTKESLAKAEAKEKELEEKMVALMQEKNDLQLQVQAEADSLADAEERCD 909
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE N L K+ R ++ EL++D++ E
Sbjct: 910 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKDIDD-------LE 961
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E L + +++ +E A + A +Q ++ +
Sbjct: 962 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1021
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIAL-LQASRADID 3750
+ + K K +QV++L +EQ KK R LE+ + + + + +AQE + ++ + +D
Sbjct: 1022 TLTKAKTKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGD-LKLAQESTMDIENDKQQLD 1080
Query: 3751 KKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLA 3930
+K K E + +Q+ + E ++ L QL++ EL R+ E EE A R
Sbjct: 1081 EKLKKKEFEMSNLQSKI----EDEQALAMQLQKKIKELQ--ARIEELEEEIEAERASRAK 1134
Query: 3931 TAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQ 4110
RL+ A + Q+E +++K EAE
Sbjct: 1135 AEKQRSDLSRELEEISERLEEAGGATSAQIE------MNKKREAE--------------- 1173
Query: 4111 GAGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELE 4281
+ RR EE+ Q LRKK+ V L +Q++ + K+++ + K +++ E++
Sbjct: 1174 -FQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSELKMEID 1232
Query: 4282 DSSMELENVRASHRDSEKRQKKFESQMAEERVAVQK-ALLDRDAMSQELRDRETRVLSLL 4458
D + +E V + + EK + E Q++E + ++ L D +Q R L
Sbjct: 1233 DLASNMETVSKAKGNLEKMCRTLEDQVSELKTKEEEHQRLINDLSAQRAR--------LQ 1284
Query: 4459 NEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQME 4638
E L+E D + L + Q ++ + + E KAK +L L R +
Sbjct: 1285 TESGEFSRQLDEKDSLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSARHDCD 1344
Query: 4639 ELEDNLQIAEDARLRL---------EVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRD 4791
L + + ++A+ L EV K E+D AI + E EE ++ L ++++D
Sbjct: 1345 LLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETD-AIQRTE-ELEEAKKKLAQRLQD 1402
Query: 4792 LENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIE 4971
E +E + +++++N++ +L +E N E++ +
Sbjct: 1403 AEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKHK 1462
Query: 4972 CEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKG 5151
EE E R + V+ E+ + E L + K A+G
Sbjct: 1463 YEETHAELEASQKESRSLSTEVFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG 1522
Query: 5152 GGISSE---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLN 5322
G E K+++E + ++ +++ E K + Q++L Q+ ++ ++
Sbjct: 1523 GKRIHELEKVKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSE------ID 1576
Query: 5323 QKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAA------LEAKVQYLEDQLNVEG 5484
+K + + +++ R++ + ++S + R++ A +E + +E QLN
Sbjct: 1577 RKIAEKDEEIDQLKRNHIRVVESMQSTLDAEIRSRNDAIRIKKKMEGDLNEMEIQLNHAN 1636
Query: 5485 QEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMS 5664
+ A R R + L DT +D R E KE L + L+ +++E +
Sbjct: 1637 RMAAEALRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLE 1696
Query: 5665 RERTKHRNVQREADDLLDANEQL 5733
+ + ++E LLDA+E++
Sbjct: 1697 QTERSRKVAEQE---LLDASERV 1716
Score = 126 bits (317), Expect = 6e-27
Identities = 133/753 (17%), Positives = 313/753 (40%), Gaps = 42/753 (5%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + E+ + + + + + +LE++ QE+ D+ ++ S AD ++
Sbjct: 849 EKEMANMKEEFEKTKESLAKAEAKEKELEEKMVALMQEKNDLQLQVQAEADSLADAEERC 908
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ + +E L + + DE L + ++ E A ++
Sbjct: 909 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 968
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ K A N+ + L +E L +E +K +
Sbjct: 969 KE---------------------KHATENKVKNLTEEMAGL----DETIAKLTKEKKALQ 1003
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
A Q + + E+ VN L + + K + V+ L+ LE+ + + + ++K+K++ +L
Sbjct: 1004 EAHQQTLDDLQAEEDKVNT-LTKAKTKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDL 1062
Query: 4279 ---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL 4449
++S+M++EN + D + ++K+FE + ++ ++AL + + +++++ + R+
Sbjct: 1063 KLAQESTMDIENDK-QQLDEKLKKKEFEMSNLQSKIEDEQALAMQ--LQKKIKELQARIE 1119
Query: 4450 SLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRV 4629
L E++ + ++++ R L +EL++ ++ G + + EAE MR
Sbjct: 1120 ELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR 1179
Query: 4630 QME----------------------ELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
+E EL + + + + +LE LK E D SN +
Sbjct: 1180 DLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNME 1239
Query: 4744 VEAEEKR------RGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANR 4905
++ K R L Q+ +L+ + E +R + + R +++ + GE +QL+ +
Sbjct: 1240 TVSKAKGNLEKMCRTLEDQVSELKTKEEEHQRLINDLSAQRARLQTESGEFSRQLDEKDS 1299
Query: 4906 LKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA----DRKFRAVEAEREQLRE 5073
L + E + + EE +AK +A L+ A D E E+E E
Sbjct: 1300 LVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSARHDCDLLREQYEEEQEAKAE 1359
Query: 5074 ANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAID 5253
+ +A + + E K++L ++ + C
Sbjct: 1360 LQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEK 1419
Query: 5254 KQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMA 5433
+++ Q ++E + D+ + ++++ ++ ++K K E + ++ ++ +
Sbjct: 1420 TKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKHKYEETHAELEA-SQKESR 1478
Query: 5434 ALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNL 5613
+L +V +++ + R + L++ ++D T+Q + + + +++ ++
Sbjct: 1479 SLSTEVFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKVKKQVEQ 1538
Query: 5614 KNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ L+ L+EAE + E K +Q E + +
Sbjct: 1539 EKSELQAALEEAEASLEHEEGKILRIQLELNQV 1571
Score = 113 bits (282), Expect = 6e-23
Identities = 175/894 (19%), Positives = 360/894 (39%), Gaps = 117/894 (13%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ +E + +E+D ++ ++KL + E + +Q +++ E + +L LQ
Sbjct: 1056 RKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDEQALAMQLQKKIKELQ 1115
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + +R S R ++E + + +
Sbjct: 1116 ARIEELEEEIE--AERASRAKAEKQRSDLSR--ELEEISERLEEAGGATSAQIEMNKKRE 1171
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K L+
Sbjct: 1172 AEFQKMRRDLEEATLQHEATAATLRKKHADSVAELG---EQIDNLQRVKQKLEKEKSELK 1228
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K LE+ R L ++ + K E + +L+ Q + E
Sbjct: 1229 MEIDDLASNMETVSKAKGNLEKMCRTLEDQVSELKTKEEEHQRLINDLSAQRARLQTESG 1288
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ DE+ + V+ + + + I+EL+ +E E A++ + + ++
Sbjct: 1289 EFSRQLDEKDSLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSARHDCDLLRE 1348
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
++ + LQ MS+ + EV TK + IQ T E +EE K K ++++++ +
Sbjct: 1349 QYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQDAEEH 1406
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME-------I 3789
+E + + LEK + + E D+ ++ A+ A +DKK++ + L E
Sbjct: 1407 VEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKHKYEET 1466
Query: 3790 QANLAESDEHKRTL--------------IDQLERSRDE---------------------L 3864
A L S + R+L +DQLE + E +
Sbjct: 1467 HAELEASQKESRSLSTEVFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRI 1526
Query: 3865 DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALL 4044
L +V+++ E + +Q L A R+++ +N+ + D K A
Sbjct: 1527 HELEKVKKQVEQEKSELQAALEEAEASLEHEEGKIL---RIQL-ELNQVKSEIDRKIAEK 1582
Query: 4045 DEKEE---------AEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN----- 4182
DE+ + E +++ L+ EI + R A ++K E +N+ +L N
Sbjct: 1583 DEEIDQLKRNHIRVVESMQSTLDAEIRS-RNDAIRIKKKMEGDLNEMEIQLNHANRMAAE 1641
Query: 4183 -LRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSM-------ELENVRASHRDSEKR 4338
LR+ + Q L+++++ + L+ ++ ++++L E+E +RA+ +E+
Sbjct: 1642 ALRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQTERS 1701
Query: 4339 QKKFESQM--AEERVAV----------QKALLDRDAMS---------QELRDRETRVLSL 4455
+K E ++ A ERV + K L+ D QE R+ E +
Sbjct: 1702 RKVAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKA 1761
Query: 4456 LNEVDIMKEHLEES-------DRVRRSLQQELQDSISNKDDFG--------KNVHELEKA 4590
+ + +M E L++ +R++++++Q ++D D+ K + +LE
Sbjct: 1762 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQKLEAR 1821
Query: 4591 KRSLEAELNDMRVQMEELEDNL------------QIAEDAR--LRLEVTNQALKSESDRA 4728
R LEAE+ + + E L Q ED + LRL+ L+++ ++
Sbjct: 1822 VRELEAEVESEQKRNVEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKV-KS 1880
Query: 4729 ISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
+ EAEE+ L + R L++ELE + A S K+ + E+ ++
Sbjct: 1881 YKRQAEEAEEQCNINLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKV 1934
Score = 71.6 bits (174), Expect = 2e-10
Identities = 95/453 (20%), Positives = 189/453 (40%), Gaps = 36/453 (7%)
Frame = +1
Query: 4492 ESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAE- 4668
E+++ ++++E + + + ELE+ +L E ND+++Q++ D+L AE
Sbjct: 847 ETEKEMANMKEEFEKTKESLAKAEAKEKELEEKMVALMQEKNDLQLQVQAEADSLADAEE 906
Query: 4669 --DARLRLEVTNQA-LKSESDRAISNKDVEAE--EKRRGLLKQIRDLENELENEKRGKSG 4833
D ++ ++ +A +K ++RA +++ AE K+R L + +L+ ++++ + +
Sbjct: 907 RCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAK 966
Query: 4834 AVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAAL 5013
+ EN++ L +++ +E E + + QA+ED
Sbjct: 967 VEKEKHATENKVKNLTEEMAGL----DETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNT 1022
Query: 5014 LREADRKFRA----VEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRR 5181
L +A K +E EQ ++ L +A+++ +K++
Sbjct: 1023 LTKAKTKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMD----IENDKQQ 1078
Query: 5182 LEAKIAQXXXXXXXXQSNCE----LAIDKQRK---AQVQLEQITTDLSMERTLNQKTEAE 5340
L+ K+ + QS E LA+ Q+K Q ++E++ ++ ER K E +
Sbjct: 1079 LDEKLKKKEFEMSNLQSKIEDEQALAMQLQKKIKELQARIEELEEEIEAERASRAKAEKQ 1138
Query: 5341 KQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRA-AR 5517
+ L R + ++ E GA S EA+ Q + L +E T + A A
Sbjct: 1139 RSDLSRELEEISERLEE-AGGATSAQIEMNKKREAEFQKMRRDL----EEATLQHEATAA 1193
Query: 5518 RLEKRLNDTTQQFEDEKRANEQAKELL--EKSNLK----------------NRNLRRQLD 5643
L K+ D+ + ++ ++ K+ L EKS LK NL +
Sbjct: 1194 TLRKKHADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMETVSKAKGNLEKMCR 1253
Query: 5644 EAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
ED++S +TK QR +DL +L E
Sbjct: 1254 TLEDQVSELKTKEEEHQRLINDLSAQRARLQTE 1286
>gi|1346637|sp|P02565|MYH3_CHICK Myosin heavy chain, fast skeletal
muscle, embryonic
gi|212376|gb|AAA48972.1| myosin heavy chain
Length = 1940
Score = 1109 bits (2869), Expect = 0.0
Identities = 645/1894 (34%), Positives = 1063/1894 (56%), Gaps = 20/1894 (1%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V E ++ +I+ + + +V V+ + +T+ D + NPPK+DKIEDM+ +T+L
Sbjct: 39 FVVHAKESYVKSTIQSKESGKVTVK-TEGGETLTVKEDQIFSMNPPKYDKIEDMAMMTHL 97
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 98 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVLAYRGKKRQEAPPHIFS 157
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A + K
Sbjct: 158 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAASGDKKK---------- 207
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
++ G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 208 EEQPAGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIE 267
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPNV 981
YLLEKSRV Q + ERS+HIFYQI+ E E LL + +Y+++ IT+P++
Sbjct: 268 TYLLEKSRVTFQLKAERSYHIFYQIMSN-KKPELIEMLLITTNPYDYQYVSQGEITVPSI 326
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
+D +E +T +++ I+GF DE ++I ++ AV+ GNL+F Q+++ +QA V K
Sbjct: 327 NDQEELMATDSAIDILGFTPDEKTAIYKLTGAVMHYGNLKFKQKQREEQAEPGGTEVADK 386
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L+GL +L KA PR+KVG E+V K Q +Q +V A+AK+ +E++F W+V RI
Sbjct: 387 AAYLMGLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNSVGALAKSVFEKMFLWMVVRI 446
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 447 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H K
Sbjct: 506 KEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNN 565
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P ++++HF++VHYAG VDY+ WL KN DPLNE VVGL Q S+ +A +
Sbjct: 566 FQKPKPGKGKAEAHFSLVHYAGTVDYNITGWLEKNKDPLNETVVGLYQKSSLKTLALL-- 623
Query: 1870 DAEFAGICAAEMNETAFGMRSRK---GMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIP 2040
FA + AE A G + K F+TVS L +E L KLM+ LR+T PHFVRC+IP
Sbjct: 624 ---FASVGGAEAESGAGGKKGGKKKGSSFQTVSALFRENLNKLMSNLRSTHPHFVRCLIP 680
Query: 2041 NHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NF 2217
N K G + LVL QLRCNGVLEGIRICR+GFP R+ + +F+ RY++L IP+ F
Sbjct: 681 NETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPIRILYADFKQRYKVLNASAIPEGQF 740
Query: 2218 IDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGF 2397
ID K++ K++ ++D+D Y+ G +KVFF+ G+L LEE RD KL LI QA+CRGF
Sbjct: 741 IDSKKASEKLLGSIDVDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQARCRGF 800
Query: 2398 LSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDE 2577
L R + N A++ +++W W +LF K+KPLL+ ++ E+ +E
Sbjct: 801 LMRVEFKKMMERRESIFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAESEKEMANMKEE 860
Query: 2578 LRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQEL 2757
TKE L K E +E E+K+ ++ E+ +Q Q+Q E++ A+ ++ +L +L
Sbjct: 861 FEKTKEELAKSEAKRKELEEKMVSLLQEKNDLQLQVQAEADGLADAEERCDQLIKTKIQL 920
Query: 2758 EYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXX 2937
E + ++ +R +RK + + +K +
Sbjct: 921 EAKIKELTERAEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKV 980
Query: 2938 XXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELE 3117
+ L E++ KAK +LE Q+ +LE
Sbjct: 981 KNLTEEMAALDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLE 1040
Query: 3118 QDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYD 3297
L +E++ + +LE+ KRKL +L+ +++ + ++L+ +L K+D E+ ++ +
Sbjct: 1041 GSLEQEKKLRMDLERAKRKLEGDLKMTQESTMDLENDKQQLDEKLKKKDFEISQIQSKIE 1100
Query: 3298 EESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVD 3477
+E A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L++
Sbjct: 1101 DEQALGMQLQKKIKELQARIEELEEEIEAERTSRAKAEKHRADLSRELEEI-SERLEEAG 1159
Query: 3478 EATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQR 3654
AT Q D+ +++ E +R +E+ E + K + ++ +QI+ ++ +
Sbjct: 1160 GATAAQIDMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSTADVGEQIDNLQRVK 1219
Query: 3655 SQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLI 3834
+LEK++++ E D+A + + ++A+++K + E L EI+ + +E +RT+
Sbjct: 1220 QKLEKEKSELKMEIDDLASNMESVSKAKANLEKMCRSLEDQLSEIK---TKEEEQQRTIN 1276
Query: 3835 D---QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANIN 4005
D Q R + E +R EE++ + + R + K +
Sbjct: 1277 DISAQKARLQTESGEYSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKKCPAH 1336
Query: 4006 RARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNL 4185
+ + + L ++ EE + + L++ + A + R K E Q+ EEL +
Sbjct: 1337 ALQSARHDCDLLREQYEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKK 1396
Query: 4186 RDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFES 4356
+ + LQ E E + + ++K+++Q E+ED +++E A+ +K+QK F+
Sbjct: 1397 KLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACAALDKKQKNFDK 1456
Query: 4357 QMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQD 4536
++E + ++ + +A +E R T + + N + +HLE R ++LQQE+ D
Sbjct: 1457 ILSEWKQKYEETQAELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEISD 1516
Query: 4537 SISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSE 4716
+ GK +HELEK K+ +E E ++++ +EE E +L+ E LR+++ +KS+
Sbjct: 1517 LTEQIAEGGKAIHELEKVKKQIEQEKSELQTALEEAEASLEHEEGKILRVQLELNQVKSD 1576
Query: 4717 SDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEV 4896
DR I+ KD E ++ +R L+ + +++ L+ E R ++ A+ +KK+E + E+E QL
Sbjct: 1577 IDRKIAEKDEEIDQLKRNHLRVVDSMQSTLDAEIRSRNEALRLKKKMEGDLNEIEIQLSH 1636
Query: 4897 ANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREA 5076
ANR E + QI ++A +++ED+ + +R+ ++AE E+LR A
Sbjct: 1637 ANRQAAEAQKNLRNTQGVLKDTQIHLDDALRSQEDLKEQVAMVERRANLLQAEIEELRAA 1696
Query: 5077 NEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELA 5247
E ++RK Q K++LE+ I+Q A
Sbjct: 1697 LEQTERSRKVAEQELLDASERVQLLHTQNTSLINTKKKLESDISQIQSEMEDTIQEARNA 1756
Query: 5248 IDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQ 5427
+K +KA + +L E+ + E K++L+++ +D + ++ E E A + Q
Sbjct: 1757 EEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLDQTVKDLQHRLDEAEQLALKGGKKQ 1816
Query: 5428 MAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKS 5607
+ LEA+V+ LE +++ E + A + R+ E+R+ + T Q E++++ + ++L++K
Sbjct: 1817 IQKLEARVRELEGEVDAEQKRSAEAVKGVRKYERRVKELTYQSEEDRKNVLRLQDLVDKL 1876
Query: 5608 NLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+K ++ +RQ +EAE+ + +K R +Q E ++
Sbjct: 1877 QMKVKSYKRQAEEAEELSNVNLSKFRKIQHELEE 1910
Score = 161 bits (408), Expect = 2e-37
Identities = 187/943 (19%), Positives = 397/943 (41%), Gaps = 57/943 (6%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + + +++L + + ELE+ LL E D + + A+ + EE +
Sbjct: 852 KEMANMKEEFEKTKEELAKSEAKRKELEEKMVSLLQEKNDLQLQVQAEADGLADAEERCD 911
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE N L K+ R ++ EL++D++ E
Sbjct: 912 QLIKTKIQLEAKIKELTERAEDEEEMNAELTAKK-RKLEDECSELKKDIDD-------LE 963
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E L + +++ +E A + A +Q ++ +
Sbjct: 964 LTLAKVEKEKHATENKVKNLTEEMAALDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1023
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIAL-LQASRADID 3750
+ + K K +QV++L +EQ KK R LE+ + + + + M QE + L+ + +D
Sbjct: 1024 TLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGD-LKMTQESTMDLENDKQQLD 1082
Query: 3751 KKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLA 3930
+K K + + +IQ+ + E ++ L QL++ EL R+ E EE A R
Sbjct: 1083 EKLKKKDFEISQIQSKI----EDEQALGMQLQKKIKELQ--ARIEELEEEIEAERTSRAK 1136
Query: 3931 TAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQ 4110
RL+ A A Q++ +++K EAE
Sbjct: 1137 AEKHRADLSRELEEISERLEEAGGATAAQID------MNKKREAE--------------- 1175
Query: 4111 GAGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELE 4281
+ RR EE+ Q LRKK+ + +Q++ + K+++ + K +++ E++
Sbjct: 1176 -FQKMRRDLEEATLQHEATAAALRKKHADSTADVGEQIDNLQRVKQKLEKEKSELKMEID 1234
Query: 4282 DSSMELENVRASHRDSEKRQKKFESQMAEER------------VAVQKALLDRDA--MSQ 4419
D + +E+V + + EK + E Q++E + ++ QKA L ++ S+
Sbjct: 1235 DLASNMESVSKAKANLEKMCRSLEDQLSEIKTKEEEQQRTINDISAQKARLQTESGEYSR 1294
Query: 4420 ELRDRETRVLSL-------LNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHE 4578
++ +++ + L +++ +K HLEE + ++ LQ + + D + E
Sbjct: 1295 QVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKKCPAHALQSARHDCDLLREQYEE 1354
Query: 4579 LEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDR---------AI 4731
++AK L+ L+ + E + + DA R E +A K + R A+
Sbjct: 1355 EQEAKGELQRALS--KANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAV 1412
Query: 4732 SNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLK 4911
++K E+ ++ L ++ DL ++E + +K + + E +Q+ E
Sbjct: 1413 NSKCASLEKTKQRLQNEVEDLMIDVERSNAACAALDKKQKNFDKILSEWKQKYE------ 1466
Query: 4912 EEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLM 5091
E Q E E +++ ++ L + + E L+ N+ L
Sbjct: 1467 ---------------ETQAELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQ 1511
Query: 5092 QARKQXXXXXXXXXXXRAKGGGISSE---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQR 5262
Q A+GG E K+++E + ++ +++ E K
Sbjct: 1512 QEISDLTEQI-------AEGGKAIHELEKVKKQIEQEKSELQTALEEAEASLEHEEGKIL 1564
Query: 5263 KAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAAL- 5439
+ Q++L Q+ +D +++K + + +++ R++ + ++S + R++ AL
Sbjct: 1565 RVQLELNQVKSD------IDRKIAEKDEEIDQLKRNHLRVVDSMQSTLDAEIRSRNEALR 1618
Query: 5440 -----EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEK 5604
E + +E QL+ ++ A + R + L DT +D R+ E KE +
Sbjct: 1619 LKKKMEGDLNEIEIQLSHANRQAAEAQKNLRNTQGVLKDTQIHLDDALRSQEDLKEQVAM 1678
Query: 5605 SNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQL 5733
+ L+ +++E + + + ++E LLDA+E++
Sbjct: 1679 VERRANLLQAEIEELRAALEQTERSRKVAEQE---LLDASERV 1718
Score = 134 bits (337), Expect = 3e-29
Identities = 171/891 (19%), Positives = 364/891 (40%), Gaps = 86/891 (9%)
Frame = +1
Query: 3325 QKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVD-EATMLQDL 3501
+K+M +M+ ++ +E++ R + E E + L + K D+ +V EA L D
Sbjct: 851 EKEMANMKEEFEKTKEELAKSEAKRKELE----EKMVSLLQEKNDLQLQVQAEADGLADA 906
Query: 3502 MSRKDEEVNA-----------TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKK 3648
R D+ + T+RA ++ + M ++ +K K + EL I+ +
Sbjct: 907 EERCDQLIKTKIQLEAKIKELTERAEDEEE--MNAELTAKKRKLEDECSELKKDIDDLEL 964
Query: 3649 QRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRK-IHEAHLMEIQANLAESDEHKR 3825
+++EK+++ + + ++ +E+A L + A + K++K + EAH + AE D+
Sbjct: 965 TLAKVEKEKHATENKVKNLTEEMAALDETIAKLTKEKKALQEAHQQTLDDLQAEEDK-VN 1023
Query: 3826 TLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANIN 4005
TL + ++D L E+E+ +++R A
Sbjct: 1024 TLTKAKTKLEQQVDDLEGSLEQEKKLRMDLER------------------------AKRK 1059
Query: 4006 RARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNL 4185
L+ + + +D + + + L L+K+ Q +++ + E+++ QL++ K+
Sbjct: 1060 LEGDLKMTQESTMDLENDKQQLDEKLKKKDFEISQI--QSKIEDEQALGMQLQKKIKELQ 1117
Query: 4186 RDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMA 4365
+E L++++E ++ + + + + +ELE+ S LE + KK E++
Sbjct: 1118 ARIEELEEEIEAERTSRAKAEKHRADLSRELEEISERLEEAGGATAAQIDMNKKREAEFQ 1177
Query: 4366 EERVAVQKALLDRDAMSQELRDRETRVLSLLNE-VDIMKEHLEESDRVRRSLQQELQDSI 4542
+ R +++A L +A + LR + + + E +D ++ ++ ++ + L+ E+ D
Sbjct: 1178 KMRRDLEEATLQHEATAAALRKKHADSTADVGEQIDNLQRVKQKLEKEKSELKMEIDDLA 1237
Query: 4543 SNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQ--IAEDARLRLEVTNQALKSE 4716
SN + K LEK RSLE +L++++ + EE + + A+ ARL+ E E
Sbjct: 1238 SNMESVSKAKANLEKMCRSLEDQLSEIKTKEEEQQRTINDISAQKARLQTE------SGE 1291
Query: 4717 SDRAISNKDVEAEEKRRG---LLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQ 4887
R + KD + RG +QI +L+ LE E + K + + L +Q
Sbjct: 1292 YSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKKCPAHALQSARHDCDLLREQ 1351
Query: 4888 LEVANRLKEEYXXXXXXXXXXXXEYQIE--------CEEARQAKEDIAALLREADRKFRA 5043
E K E +++ + EE +AK+ +A L++A+ A
Sbjct: 1352 YEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEA 1411
Query: 5044 V-------EAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQ 5202
V E +++L+ E LM ++ + I SE K++ E A+
Sbjct: 1412 VNSKCASLEKTKQRLQNEVEDLMIDVERSNAACAALDKKQKNFDKILSEWKQKYEETQAE 1471
Query: 5203 XXXXXXXXQS-----------------NCELAIDKQRKAQVQLEQITTDLSMERTLNQKT 5331
+S + E + + Q ++ +T ++ +
Sbjct: 1472 LEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKAIHEL 1531
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRA----RAQMAALEAK----------------- 5448
E K+ +E+ + + + E E+ + R Q+ + K
Sbjct: 1532 EKVKKQIEQEKSELQTALEEAEASLEHEEGKILRVQLELNQVKSDIDRKIAEKDEEIDQL 1591
Query: 5449 -------VQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKS 5607
V ++ L+ E + + A R +++E LN+ Q R +A++ L +
Sbjct: 1592 KRNHLRVVDSMQSTLDAEIRSRNEALRLKKKMEGDLNEIEIQLSHANRQAAEAQKNLRNT 1651
Query: 5608 NLKNRNLRRQLDEA-------EDEMSRERTKHRNVQREADDLLDANEQLTR 5739
++ + LD+A +++++ + +Q E ++L A EQ R
Sbjct: 1652 QGVLKDTQIHLDDALRSQEDLKEQVAMVERRANLLQAEIEELRAALEQTER 1702
Score = 115 bits (287), Expect = 2e-23
Identities = 173/910 (19%), Positives = 359/910 (39%), Gaps = 132/910 (14%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ T+E + +E+D ++ ++KL + E + IQ +++ E +L LQ
Sbjct: 1058 RKLEGDLKMTQESTMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQ 1117
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + +R S R ++E + + +
Sbjct: 1118 ARIEELEEEIE--AERTSRAKAEKHRADLSR--ELEEISERLEEAGGATAAQIDMNKKRE 1173
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K L+
Sbjct: 1174 AEFQKMRRDLEEATLQHEATAAALRKKHADSTADVG---EQIDNLQRVKQKLEKEKSELK 1230
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K+ LE+ R L +L + K E+ + +++ Q + E
Sbjct: 1231 MEIDDLASNMESVSKAKANLEKMCRSLEDQLSEIKTKEEEQQRTINDISAQKARLQTESG 1290
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ +E+ A ++ + + + I+EL+ +E E A+ + + ++
Sbjct: 1291 EYSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKKCPAHALQSARHDCDLLRE 1350
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
++ + LQ +S+ + EV TK + IQ T E +EE K K ++++++ +
Sbjct: 1351 QYEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQDAEEH 1408
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME-------I 3789
+E + + LEK + + E D+ ++ A+ A +DKK+K + L E
Sbjct: 1409 VEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACAALDKKQKNFDKILSEWKQKYEET 1468
Query: 3790 QANLAESDEHKRTL--------------IDQLERSRDE---------------------L 3864
QA L S + R+L +D LE + E +
Sbjct: 1469 QAELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKAI 1528
Query: 3865 DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKI----ANINRARQLEDE- 4029
L +V+++ E + +Q L A +L++ ++I+R +DE
Sbjct: 1529 HELEKVKKQIEQEKSELQTALEEAEASLEHEEGKILR-VQLELNQVKSDIDRKIAEKDEE 1587
Query: 4030 -------------------------KNALLDEKEEAEGLRAHLEKEIHAARQGAGEARR- 4131
+N L K++ EG +E ++ A + A EA++
Sbjct: 1588 IDQLKRNHLRVVDSMQSTLDAEIRSRNEALRLKKKMEGDLNEIEIQLSHANRQAAEAQKN 1647
Query: 4132 -------------------KAEESVNQQLEEL-RKKNLRDVEHLQKQLEESEVAKERILQ 4251
+++E + +Q+ + R+ NL LQ ++EE A E+ +
Sbjct: 1648 LRNTQGVLKDTQIHLDDALRSQEDLKEQVAMVERRANL-----LQAEIEELRAALEQTER 1702
Query: 4252 SKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRD 4431
S+K +QEL D+S ++ + + +KK ES +++ + ++ + QE R+
Sbjct: 1703 SRKVAEQELLDASERVQLLHTQNTSLINTKKKLESDISQIQSEMEDTI-------QEARN 1755
Query: 4432 RETRVLSLLNEVDIMKEHLEES-------DRVRRSLQQELQDSISNKDDFG--------K 4566
E + + + +M E L++ +R++++L Q ++D D+ K
Sbjct: 1756 AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLDQTVKDLQHRLDEAEQLALKGGKK 1815
Query: 4567 NVHELEKAKRSLEAELN---------------------DMRVQMEELEDNLQIAEDARLR 4683
+ +LE R LE E++ ++ Q EE N+ +D +
Sbjct: 1816 QIQKLEARVRELEGEVDAEQKRSAEAVKGVRKYERRVKELTYQSEEDRKNVLRLQDLVDK 1875
Query: 4684 LEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIEN 4863
L++ ++ K +++ EAEE L + R +++ELE + A S K+
Sbjct: 1876 LQMKVKSYKRQAE--------EAEELSNVNLSKFRKIQHELEEAEERADIAESQVNKLRA 1927
Query: 4864 QIGELEQQLE 4893
+ E+ ++ E
Sbjct: 1928 KSREIGKKAE 1937
Score = 73.9 bits (180), Expect = 4e-11
Identities = 98/457 (21%), Positives = 196/457 (42%), Gaps = 40/457 (8%)
Frame = +1
Query: 4492 ESDRVRRSLQQELQDSISNKDDFGKNV---HELEKAKRSLEAELNDMRVQMEELEDNLQI 4662
ES++ ++++E + + K++ K+ ELE+ SL E ND+++Q++ D L
Sbjct: 849 ESEKEMANMKEEFEKT---KEELAKSEAKRKELEEKMVSLLQEKNDLQLQVQAEADGLAD 905
Query: 4663 AE---DARLRLEVTNQA-LKSESDRAISNKDVEAE--EKRRGLLKQIRDLENELENEKRG 4824
AE D ++ ++ +A +K ++RA +++ AE K+R L + +L+ ++++ +
Sbjct: 906 AEERCDQLIKTKIQLEAKIKELTERAEDEEEMNAELTAKKRKLEDECSELKKDIDDLELT 965
Query: 4825 KSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDI 5004
+ + EN++ L +++ +E E + + QA+ED
Sbjct: 966 LAKVEKEKHATENKVKNLTEEMAAL----DETIAKLTKEKKALQEAHQQTLDDLQAEEDK 1021
Query: 5005 AALLREADRKFRA----VEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEE 5172
L +A K +E EQ ++ L +A+++ +
Sbjct: 1022 VNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKMTQESTMD----LEND 1077
Query: 5173 KRRLEAKIAQXXXXXXXXQSNCE----LAIDKQRKA---QVQLEQITTDLSMERTLNQKT 5331
K++L+ K+ + QS E L + Q+K Q ++E++ ++ ERT K
Sbjct: 1078 KQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERTSRAKA 1137
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRARAQM-AALEAKVQYLEDQLNVEGQEKTAANR 5508
E + L R + ++ E +G + A+ M EA+ Q + L +E T +
Sbjct: 1138 EKHRADLSRELEEISERLEE--AGGATAAQIDMNKKREAEFQKMRRDL----EEATLQHE 1191
Query: 5509 A-ARRLEKRLNDTTQQFEDEKRANEQAKELLEK-------------SNLKN-----RNLR 5631
A A L K+ D+T ++ ++ K+ LEK SN+++ NL
Sbjct: 1192 ATAAALRKKHADSTADVGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMESVSKAKANLE 1251
Query: 5632 RQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
+ ED++S +TK QR +D+ +L E
Sbjct: 1252 KMCRSLEDQLSEIKTKEEEQQRTINDISAQKARLQTE 1288
Score = 54.7 bits (130), Expect = 3e-05
Identities = 71/329 (21%), Positives = 136/329 (40%), Gaps = 31/329 (9%)
Frame = +1
Query: 4852 KIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADR 5031
KI+ + E + E+AN +KEE+ + ++ +E + +LL+E +
Sbjct: 840 KIKPLLKSAESEKEMAN-MKEEFEKTKEELAKSEAK-------RKELEEKMVSLLQEKND 891
Query: 5032 KFRAVEAEREQLREANEG---LMQARKQXXXXXXXXXXXRAKGGGISSE---EKRRLEAK 5193
V+AE + L +A E L++ + Q +++E +KR+LE +
Sbjct: 892 LQLQVQAEADGLADAEERCDQLIKTKIQLEAKIKELTERAEDEEEMNAELTAKKRKLEDE 951
Query: 5194 IAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEA----EKQSLERS 5361
++ + EL + K K + E +L+ E +T A EK++L+ +
Sbjct: 952 CSELKKDI----DDLELTLAKVEKEKHATENKVKNLTEEMAALDETIAKLTKEKKALQEA 1007
Query: 5362 NRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLND 5541
++ + E + +A+ LE +V LE L E + + RA R+LE L
Sbjct: 1008 HQQTLDDLQAEEDKVNTLTKAK-TKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKM 1066
Query: 5542 TTQQFEDEKRANEQAKELLEKSNL---------------------KNRNLRRQLDEAEDE 5658
T + D + +Q E L+K + K + L+ +++E E+E
Sbjct: 1067 TQESTMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQARIEELEEE 1126
Query: 5659 MSRERTKHRNVQREADDLLDANEQLTREL 5745
+ ERT ++ DL E+++ L
Sbjct: 1127 IEAERTSRAKAEKHRADLSRELEEISERL 1155
Score = 38.1 bits (87), Expect = 2.6
Identities = 48/284 (16%), Positives = 102/284 (35%), Gaps = 4/284 (1%)
Frame = +1
Query: 2548 DDEIRAKDD---ELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELD 2718
DD +R+++D ++ + R ++ + E L+Q R V +++L SE L
Sbjct: 1663 DDALRSQEDLKEQVAMVERRANLLQAEIEELRAALEQTERSRKVAEQELLDASERVQLLH 1722
Query: 2719 DIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXX 2898
L ++LE ++ ++ + +K +
Sbjct: 1723 TQNTSLINTKKKLESDISQIQSEMEDTIQEARNAEEKAKKAITDAAMMAEELKKEQDTSA 1782
Query: 2899 XXXXDKTNVDQXXXXXXXXXXXXQD-AYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV 3075
K N+DQ + A L ++ ++R+ V
Sbjct: 1783 HLERMKKNLDQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVDAEQKRSAEAV 1842
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLM 3255
K + E ++ EL +R+ L+ KL +++ K E EEL+N +
Sbjct: 1843 KGVRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQMKVKSYKRQAEE----AEELSNVNL 1898
Query: 3256 KRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETE 3387
+ ++QH+L +E + + Q+ ++ E+ + E+E
Sbjct: 1899 SKFRKIQHEL---EEAEERADIAESQVNKLRAKSREIGKKAESE 1939
>gi|6683485|dbj|BAA89233.1| skeletal myosin heavy chain [Gallus
gallus]
Length = 1939
Score = 1108 bits (2867), Expect = 0.0
Identities = 646/1891 (34%), Positives = 1057/1891 (55%), Gaps = 17/1891 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V E ++ +I+ + + +V V+ ++ +T+ D + NPPK+DKIEDM+ +T+L
Sbjct: 39 FVVHAKESYVKSTIQSKESGKVTVK-TESGETLTVKEDQIFSMNPPKYDKIEDMAMMTHL 97
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 98 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVLAYRGKKRQEAPPHIFS 157
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A + K
Sbjct: 158 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAASGDKKK---------- 207
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
++ G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 208 EEQPAGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIE 267
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPNV 981
YLLEKSRV Q + ERS+HIFYQI+ E E LL + +Y ++ IT+P++
Sbjct: 268 TYLLEKSRVTFQLKAERSYHIFYQIMSN-KKPELIEMLLITTNPYDYHYVSQGEITVPSI 326
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
+D +E +T +++ I+GF DE ++I ++ AV+ GNL+F Q+++ +QA V K
Sbjct: 327 NDQEELMATDSAIDILGFTPDEKTAIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADK 386
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L+GL +L KA PR+KVG EFV K Q +Q +V A+AKA +E++F W+V RI
Sbjct: 387 AAYLMGLNSADLLKALCYPRVKVGNEFVTKGQTVQQVYNSVGALAKAVFEKMFLWMVVRI 446
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 447 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H K
Sbjct: 506 KEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNN 565
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P ++++HF++VHYAG VDY+ WL KN DPL E VVGL Q S+ +A ++
Sbjct: 566 FQKPKPGKGKAEAHFSLVHYAGTVDYNISGWLDKNKDPLYETVVGLYQKSSLKTLALLFA 625
Query: 1870 DAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHE 2049
AG A G + + F+TVS L +E L KLMT LR+T PHFVRCIIPN
Sbjct: 626 S---AGGEAESGGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 682
Query: 2050 KKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDG 2226
K G + LVL QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L IP+ FID
Sbjct: 683 KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDS 742
Query: 2227 KESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSR 2406
K++ K++ ++D+D Y+ G +KVFF+ G+L LEE RD KL LI QA+CRGFL R
Sbjct: 743 KKASEKLLGSIDVDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQARCRGFLMR 802
Query: 2407 RLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRA 2586
Y N +++ +++W W +LF K+KPLL+ ++ E+ E
Sbjct: 803 VEYRRMVERRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAESEKEMANMKGEFEK 862
Query: 2587 TKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYI 2766
TKE L K ++ E K+ ++ E+ +Q Q+Q E++ A+ ++ +L +LE
Sbjct: 863 TKEELAKSGAKRKDLEGKMVSLLQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEAK 922
Query: 2767 VNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXX 2946
+ ++ +R +RK + + +K +
Sbjct: 923 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 982
Query: 2947 XXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDL 3126
+ L E++ KAK +LE Q+ +LE L
Sbjct: 983 TEEMAALDENIAKLTKEKKAPQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSL 1042
Query: 3127 NRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEES 3306
+E++ + +LE+ KRKL +L+ + D + + ++L+ +L K+D E+ ++ ++E
Sbjct: 1043 EQEKKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQ 1102
Query: 3307 ANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT 3486
A +QK+++++Q +EL E++E ER +R KAE R ++ +LE++ + L++ AT
Sbjct: 1103 ALGMQLQKKIKELQARTEELEEEIEAERTSRAKAEKHRADLSRELEEI-SERLEEAGGAT 1161
Query: 3487 MLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQL 3663
Q D+ +++ E +R +E+ E + K + EL +QI+ ++ + +L
Sbjct: 1162 AAQIDMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKL 1221
Query: 3664 EKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLID-- 3837
EK++++ E D+A + + ++A ++K + E + EI+ + +EH+R + D
Sbjct: 1222 EKEKSELKMEIDDLASNMESVSKAKASLEKTCRALEDQMSEIK---TKEEEHQRMINDVN 1278
Query: 3838 -QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRAR 4014
Q R + E +R EE++ + + R + K A + +
Sbjct: 1279 AQRARLQTESGEYSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKNALAHGLQ 1338
Query: 4015 QLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDV 4194
+ + L ++ EE + + L++ + A + R K E Q+ EEL + +
Sbjct: 1339 SARHDCDLLREQYEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA 1398
Query: 4195 EHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMA 4365
+ LQ E E + + ++K+++Q E+ED +++E ++ +K+QK F+ ++
Sbjct: 1399 QRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERANSACAALDKKQKNFDKILS 1458
Query: 4366 EERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSIS 4545
E + ++ + +A +E R T + + N + +HLE R ++LQQE+ D
Sbjct: 1459 EWKQKYEETQAELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEISDLTE 1518
Query: 4546 NKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDR 4725
+ GK +HELEK K+ +E E ++++ +EE E +L+ E LRL++ +KSE DR
Sbjct: 1519 QIAEGGKAIHELEKVKKQIEQEKSELQASLEEAEASLEHEEGKILRLQLELNQVKSEIDR 1578
Query: 4726 AISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANR 4905
I+ KD E ++ +R L+ + ++ L+ E R ++ A+ +KK+E + E+E QL ANR
Sbjct: 1579 KIAEKDEEIDQLKRNHLRIVESMQRTLDAEVRSRNEALRLKKKMEGDLNEMEIQLNHANR 1638
Query: 4906 LKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEG 5085
+ E + QI ++A +++ED+ + +R+ ++AE E+LR A E
Sbjct: 1639 MAAEAQKNLRNTQGVLKDTQIHLDDALRSQEDLKEQVAMVERRANLLQAETEELRAALEQ 1698
Query: 5086 LMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDK 5256
++RK Q K++LE+ I+Q A +K
Sbjct: 1699 TERSRKVAEQELLDASERVQLLHTQNTSLINTKKKLESDISQIQSEMEDTIQEARNAEEK 1758
Query: 5257 QRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAA 5436
+KA + +L E+ + E K++L+++ +D + ++ E E A + Q+
Sbjct: 1759 AKKAITDAAMMAEELKKEQDTSAHLERMKKNLDQTVKDLQHRLDEAEQLALKGGKKQIQK 1818
Query: 5437 LEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLK 5616
LEA+V+ LE +++ E + A + R+ E+R+ + T Q E++++ + ++L++K +K
Sbjct: 1819 LEARVRELEGEVDAEQKRSAEAVKGVRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQMK 1878
Query: 5617 NRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
++ +RQ +EAE+ + +K R +Q E ++
Sbjct: 1879 VKSYKRQAEEAEELSNVNLSKFRKIQHELEE 1909
Score = 157 bits (398), Expect = 2e-36
Identities = 197/948 (20%), Positives = 391/948 (40%), Gaps = 50/948 (5%)
Frame = +1
Query: 3040 LLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSE---LEQHKRKLLAELEDSKDHL 3210
LL E K KG E EL + + + + + L Q K L +++ D L
Sbjct: 843 LLKSAESEKEMANMKGEFEKTKEELAKSGAKRKDLEGKMVSLLQEKNDLQLQVQAEADAL 902
Query: 3211 AEKMGKVEELNNQLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELRED 3375
A+ EE +QL+K +L+ ++ DEE N L K+ R ++ EL++D
Sbjct: 903 AD----AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKD 957
Query: 3376 METERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQI 3555
++ E+T +V + + V + +E L + +++ +E A + A +Q
Sbjct: 958 IDD-------LELTLAKVEKEKHATENKVKNLTEEMAALDENIAKLTKEKKAPQEAHQQT 1010
Query: 3556 QHTMEGK------IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEI 3717
++ + + + K K +QV++L +EQ KK R LE+ + + + + I
Sbjct: 1011 LDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAHDSI 1070
Query: 3718 ALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEE 3897
L+ + +D+K K + + +IQ+ + E ++ L QL++ EL R E EE
Sbjct: 1071 MDLENDKQQLDEKLKKKDFEISQIQSKI----EDEQALGMQLQKKIKELQ--ARTEELEE 1124
Query: 3898 HAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRA 4077
A R RL+ A A Q++ +++K EAE
Sbjct: 1125 EIEAERTSRAKAEKHRADLSRELEEISERLEEAGGATAAQID------MNKKREAE---- 1174
Query: 4078 HLEKEIHAARQGAGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERIL 4248
+ RR EE+ Q LRKK+ L +Q++ + K+++
Sbjct: 1175 ------------FQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLE 1222
Query: 4249 QSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEER------------VAVQKA 4392
+ K +++ E++D + +E+V + EK + E QM+E + V Q+A
Sbjct: 1223 KEKSELKMEIDDLASNMESVSKAKASLEKTCRALEDQMSEIKTKEEEHQRMINDVNAQRA 1282
Query: 4393 LLDRDA--MSQELRDRETRVLSL-------LNEVDIMKEHLEESDRVRRSLQQELQDSIS 4545
L ++ S+++ +++ + L +++ +K HLEE + + +L LQ +
Sbjct: 1283 RLQTESGEYSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKNALAHGLQSARH 1342
Query: 4546 NKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDR 4725
+ D + E ++AK L+ L ++ EV K E+D
Sbjct: 1343 DCDLLREQYEEEQEAKGELQRAL-------------------SKANSEVAQWRTKYETD- 1382
Query: 4726 AISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVAN- 4902
AI + E EE ++ L ++++D E +E + +++++N++ +L +E AN
Sbjct: 1383 AIQRTE-ELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERANS 1441
Query: 4903 ------RLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQ 5064
+ ++ + E Q E E +++ ++ L + + E
Sbjct: 1442 ACAALDKKQKNFDKILSEWKQKYEETQAELEASQKESRSLSTELFKMKNAYEESLDHLET 1501
Query: 5065 LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSE---EKRRLEAKIAQXXXXXXXXQSN 5235
L+ N+ L Q A+GG E K+++E + ++ +++
Sbjct: 1502 LKRENKNLQQEISDLTEQI-------AEGGKAIHELEKVKKQIEQEKSELQASLEEAEAS 1554
Query: 5236 CELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSR 5415
E K + Q++L Q+ +++ +R + +K E Q R ++ L++ +SR
Sbjct: 1555 LEHEEGKILRLQLELNQVKSEI--DRKIAEKDEEIDQLKRNHLRIVESMQRTLDAEVRSR 1612
Query: 5416 ARA--QMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAK 5589
A +E + +E QLN + A + R + L DT +D R+ E K
Sbjct: 1613 NEALRLKKKMEGDLNEMEIQLNHANRMAAEAQKNLRNTQGVLKDTQIHLDDALRSQEDLK 1672
Query: 5590 ELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQL 5733
E + + L+ + +E + + + ++E LLDA+E++
Sbjct: 1673 EQVAMVERRANLLQAETEELRAALEQTERSRKVAEQE---LLDASERV 1717
Score = 140 bits (352), Expect = 5e-31
Identities = 180/931 (19%), Positives = 381/931 (40%), Gaps = 73/931 (7%)
Frame = +1
Query: 3166 KRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDM 3345
K K L + +S+ +A G+ E+ +L K + R D E V+L+Q++
Sbjct: 839 KIKPLLKSAESEKEMANMKGEFEKTKEELAKSGAK------RKDLEGKMVSLLQEK---- 888
Query: 3346 QTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEV 3525
++L+ ++ E +A AE E QL K K + K+ E T + +EE+
Sbjct: 889 ----NDLQLQVQAEADALADAE----ERCDQLIKTKIQLEAKIKEVTE----RAEDEEEI 936
Query: 3526 NATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADM 3705
NA ++ +K K + EL I+ + +++EK+++ + + ++
Sbjct: 937 NA--------------ELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 982
Query: 3706 AQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVR 3885
+E+A L + A + K++K A + H++TL D L+ D+++ L + +
Sbjct: 983 TEEMAALDENIAKLTKEKK-------------APQEAHQQTL-DDLQAEEDKVNTLTKAK 1028
Query: 3886 EEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAE 4065
+ E +++ L +L++ R+LE + D + E
Sbjct: 1029 TKLEQQVDDLEGSLEQEK--------------KLRMDLERAKRKLEGDLKLAHDSIMDLE 1074
Query: 4066 GLRAHLEKEIHAARQGAGEARRKAEE--SVNQQLEELRKKNLRDVEHLQKQLEESEVAKE 4239
+ L++++ + + K E+ ++ QL++ K+ E L++++E ++
Sbjct: 1075 NDKQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQARTEELEEEIEAERTSRA 1134
Query: 4240 RILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQ 4419
+ + + + +ELE+ S LE + KK E++ + R +++A L +A +
Sbjct: 1135 KAEKHRADLSRELEEISERLEEAGGATAAQIDMNKKREAEFQKMRRDLEEATLQHEATAA 1194
Query: 4420 ELRDRETRVLSLLNE-VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKR 4596
LR + + L E +D ++ ++ ++ + L+ E+ D SN + K LEK R
Sbjct: 1195 ALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMESVSKAKASLEKTCR 1254
Query: 4597 SLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRG-- 4770
+LE ++++++ + EE + + R RL+ + E R + KD + RG
Sbjct: 1255 ALEDQMSEIKTKEEEHQRMINDVNAQRARLQTES----GEYSRQVEEKDALISQLSRGKQ 1310
Query: 4771 -LLKQIRDLENELENEKRGKS----GAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXX 4935
+QI +L+ LE E + K+ G S R + + E++ E L+
Sbjct: 1311 AFTQQIEELKRHLEEEIKAKNALAHGLQSARHDCDLLREQYEEEQEAKGELQRALSKANS 1370
Query: 4936 XXXXXXXEYQIEC----EEARQAKEDIAALLREADRKFRAV-------EAEREQLREANE 5082
+Y+ + EE +AK+ +A L++A+ AV E +++L+ E
Sbjct: 1371 EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVE 1430
Query: 5083 GLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQS---------- 5232
LM ++ + I SE K++ E A+ +S
Sbjct: 1431 DLMIDVERANSACAALDKKQKNFDKILSEWKQKYEETQAELEASQKESRSLSTELFKMKN 1490
Query: 5233 -------NCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITE 5391
+ E + + Q ++ +T ++ + E K+ +E+ + +A + E
Sbjct: 1491 AYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKAIHELEKVKKQIEQEKSELQASLEE 1550
Query: 5392 LESGAQSRA----RAQMAALEAK------------------------VQYLEDQLNVEGQ 5487
E+ + R Q+ + K V+ ++ L+ E +
Sbjct: 1551 AEASLEHEEGKILRLQLELNQVKSEIDRKIAEKDEEIDQLKRNHLRIVESMQRTLDAEVR 1610
Query: 5488 EKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEA------ 5649
+ A R +++E LN+ Q R +A++ L + ++ + LD+A
Sbjct: 1611 SRNEALRLKKKMEGDLNEMEIQLNHANRMAAEAQKNLRNTQGVLKDTQIHLDDALRSQED 1670
Query: 5650 -EDEMSRERTKHRNVQREADDLLDANEQLTR 5739
+++++ + +Q E ++L A EQ R
Sbjct: 1671 LKEQVAMVERRANLLQAETEELRAALEQTER 1701
Score = 101 bits (251), Expect = 3e-19
Identities = 98/485 (20%), Positives = 208/485 (42%), Gaps = 17/485 (3%)
Frame = +1
Query: 2968 QDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYK 3147
++AY+ L ++ D E+ G KA +HELE+ K
Sbjct: 1489 KNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKA-------IHELEK-------VK 1534
Query: 3148 SELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQ 3327
++EQ K +L A LE+++ L + GK+ L +L + E+ ++ DEE +
Sbjct: 1535 KQIEQEKSELQASLEEAEASLEHEEGKILRLQLELNQVKSEIDRKIAEKDEE------ID 1588
Query: 3328 KQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMS 3507
+ R+ ++ ++ ++ E +RN+A ++++ L +++ + A Q +
Sbjct: 1589 QLKRNHLRIVESMQRTLDAEVRSRNEALRLKKKMEGDLNEMEIQLNHANRMAAEAQKNLR 1648
Query: 3508 RKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQAD 3687
+ T+ ++ + E ++EQ A R+ L + E+ + Q E+ + A+
Sbjct: 1649 NTQGVLKDTQIHLDDALRSQED-LKEQVAMVERRANLLQAETEELRAALEQTERSRKVAE 1707
Query: 3688 QERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRT------------- 3828
QE D ++ + LL + +K E+ + +IQ+ + ++ + R
Sbjct: 1708 QELLDASERVQLLHTQNTSLINTKKKLESDISQIQSEMEDTIQEARNAEEKAKKAITDAA 1767
Query: 3829 -LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANIN 4005
+ ++L++ +D HL R+++ + ++Q RL A + +I +
Sbjct: 1768 MMAEELKKEQDTSAHLERMKKNLDQTVKDLQHRLDEAEQLALKGG-------KKQIQKLE 1820
Query: 4006 -RARQLEDEKNALLDEKEEAEGLRA--HLEKEIHAARQGAGEARRKAEESVNQQLEELRK 4176
R R+LE E +A ++K AE ++ E+ + + E R+ +L++L
Sbjct: 1821 ARVRELEGEVDA--EQKRSAEAVKGVRKYERRVKELTYQSEEDRKNV-----LRLQDLVD 1873
Query: 4177 KNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFES 4356
K V+ ++Q EE+E L +KIQ ELE++ + + + ++F
Sbjct: 1874 KLQMKVKSYKRQAEEAEELSNVNLSKFRKIQHELEEAEERADIAESQVNKLRVKSREFHK 1933
Query: 4357 QMAEE 4371
++ EE
Sbjct: 1934 KIEEE 1938
Score = 68.9 bits (167), Expect = 1e-09
Identities = 96/454 (21%), Positives = 190/454 (41%), Gaps = 37/454 (8%)
Frame = +1
Query: 4492 ESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAE- 4668
ES++ +++ E + + G +LE SL E ND+++Q++ D L AE
Sbjct: 848 ESEKEMANMKGEFEKTKEELAKSGAKRKDLEGKMVSLLQEKNDLQLQVQAEADALADAEE 907
Query: 4669 --DARLRLEVTNQA-LKSESDRAISNKDVEAE--EKRRGLLKQIRDLENELENEKRGKSG 4833
D ++ ++ +A +K ++RA +++ AE K+R L + +L+ ++++ + +
Sbjct: 908 RCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAK 967
Query: 4834 AVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAAL 5013
+ EN++ L +++ +E E + + QA+ED
Sbjct: 968 VEKEKHATENKVKNLTEEMAAL----DENIAKLTKEKKAPQEAHQQTLDDLQAEEDKVNT 1023
Query: 5014 LREADRKFRA----VEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRR 5181
L +A K +E EQ ++ L +A+++ +K++
Sbjct: 1024 LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAHDSIMD----LENDKQQ 1079
Query: 5182 LEAKIAQXXXXXXXXQSNCE----LAIDKQRKA---QVQLEQITTDLSMERTLNQKTEAE 5340
L+ K+ + QS E L + Q+K Q + E++ ++ ERT K E
Sbjct: 1080 LDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQARTEELEEEIEAERTSRAKAEKH 1139
Query: 5341 KQSLERSNRDYKAKITELESGAQSRARAQM-AALEAKVQYLEDQLNVEGQEKTAANRA-A 5514
+ L R + ++ E +G + A+ M EA+ Q + L +E T + A A
Sbjct: 1140 RADLSRELEEISERLEE--AGGATAAQIDMNKKREAEFQKMRRDL----EEATLQHEATA 1193
Query: 5515 RRLEKRLNDTTQQFEDEKRANEQAKELLEK-------------SNLKN-----RNLRRQL 5640
L K+ D+T + ++ ++ K+ LEK SN+++ +L +
Sbjct: 1194 AALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMESVSKAKASLEKTC 1253
Query: 5641 DEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
ED+MS +TK QR +D+ +L E
Sbjct: 1254 RALEDQMSEIKTKEEEHQRMINDVNAQRARLQTE 1287
Score = 49.3 bits (116), Expect = 0.001
Identities = 60/325 (18%), Positives = 124/325 (37%), Gaps = 2/325 (0%)
Frame = +1
Query: 4777 KQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXX 4956
K++ +++ E E K + + + RK +E ++ L Q+ K +
Sbjct: 851 KEMANMKGEFEKTKEELAKSGAKRKDLEGKMVSLLQE-------KNDLQLQVQAEADALA 903
Query: 4957 EYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXX 5136
+ + C++ + K + A ++E + E +L L +
Sbjct: 904 DAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLEL 963
Query: 5137 XRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTD--LSME 5310
AK +EK E K+ N + K++KA + Q T D + E
Sbjct: 964 TLAK----VEKEKHATENKVKNLTEEMAALDENIA-KLTKEKKAPQEAHQQTLDDLQAEE 1018
Query: 5311 RTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQE 5490
+N T+A K LE+ D + + + + RA+ LE ++ D + +
Sbjct: 1019 DKVNTLTKA-KTKLEQQVDDLEGSLEQEKKLRMDLERAKRK-LEGDLKLAHDSIMDLEND 1076
Query: 5491 KTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRE 5670
K + ++ + ++ + EDE+ Q ++ K + L+ + +E E+E+ E
Sbjct: 1077 KQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQK-------KIKELQARTEELEEEIEAE 1129
Query: 5671 RTKHRNVQREADDLLDANEQLTREL 5745
RT ++ DL E+++ L
Sbjct: 1130 RTSRAKAEKHRADLSRELEEISERL 1154
>gi|17561652|ref|NP_505094.1| myosin heavy chain family member (5I597)
[Caenorhabditis elegans]
gi|7504673|pir||T30010 hypothetical protein F58G4.1 - Caenorhabditis
elegans
gi|10864419|gb|AAG24132.1| Hypothetical protein F58G4.1
[Caenorhabditis elegans]
Length = 1974
Score = 1108 bits (2867), Expect = 0.0
Identities = 654/1927 (33%), Positives = 1053/1927 (53%), Gaps = 29/1927 (1%)
Frame = +1
Query: 52 ATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKF 231
AT + +K WV D EGF+ IK D V+V + + TI +DD Q+ NPPK+
Sbjct: 22 ATTKKFDSKKNVWVADPEEGFIAAEIKSSKGDTVVV-VTSKGVEKTIKKDDAQQMNPPKY 80
Query: 232 DKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKG 411
+K EDM+ LT+LN+ASVLHNL+ RYYS +IYTYSGLFCVVINPYK+LPIYSE + + + G
Sbjct: 81 EKTEDMANLTFLNDASVLHNLRQRYYSMMIYTYSGLFCVVINPYKRLPIYSESVCQMYLG 140
Query: 412 KKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRN 591
K+R+EMPPH+FA++D AYR+M +RE+QS+L TGESGAGKTENTKKVI Y A V
Sbjct: 141 KRRNEMPPHLFAVSDEAYRNMTNDRENQSMLITGESGAGKTENTKKVISYFAMVG----- 195
Query: 592 KSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINF 771
A+QQ+ +K LE Q++Q NP+LEAFGN+KTV+N+NSSRFGKFIRI+F
Sbjct: 196 -----ASQQSNKKKSKKDKAQVSLEDQIVQTNPVLEAFGNAKTVRNNNSSRFGKFIRIHF 250
Query: 772 DMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGC--SAKEKSEYLLEGVDNYR 945
+ G ++GA+IE YLLEKSRV++QA ERS+HIFYQI +EK +L + Y
Sbjct: 251 NTGGKVAGADIEHYLLEKSRVIKQAPGERSYHIFYQIYSDAVKGLREKL-FLTRPIKEYT 309
Query: 946 FLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSD 1125
F+ +T+ VDD +E T + IM F E S + + + ++ +G L+F Q + +
Sbjct: 310 FVSQAEVTIDGVDDKEEMLITDEAFDIMKFTATEKSELFAITAGIMHMGELKFKQRPREE 369
Query: 1126 QAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKAS 1305
QA L++ + + C L + + A L+PR+KVG E+VNK QN +Q +AV A+AKA
Sbjct: 370 QAELEEGKEGELACKLYCVESEKFINALLKPRVKVGTEWVNKGQNLDQVNWAVGALAKAL 429
Query: 1306 YERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFN 1485
+ R+F WL+ R NK+LD FIG+LDIAGFEIFD+NSFEQ+ IN+ NEKLQQ FN
Sbjct: 430 FARMFSWLIRRCNKTLDAQDLSRDFFIGVLDIAGFEIFDLNSFEQLWINFVNEKLQQFFN 489
Query: 1486 NTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVE 1665
+ MF+LEQEEY+REGI+W+FIDFGLDLQ I+LIEKP+G++++LDEEC+ PKA+D +
Sbjct: 490 HHMFVLEQEEYKREGIQWEFIDFGLDLQACIELIEKPLGIVSMLDEECIVPKASDLTLAS 549
Query: 1666 KLQKTH-NKHPKFIVP----DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLM 1830
KL H KHP F P ++++H A+VHYAG V Y+ WL KN DPLN+ V ++
Sbjct: 550 KLNDQHLGKHPNFQKPRPPKGKQAEAHLAIVHYAGTVRYNVKGWLEKNKDPLNDTAVTVL 609
Query: 1831 Q-NSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKG---MFRTVSQLHKEQLTKLMTT 1998
+ N + +A +W D AA + + +KG F TVS +++E L KLM
Sbjct: 610 KANKGNQLMADLWADYATQEDVAAAAKDGKKAVGKKKGKSASFMTVSMMYRESLNKLMHM 669
Query: 1999 LRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHR 2178
L T PHF+RCIIPN KK+G I++NLVL QL CNGVLEGIRICR+GFPNR+PF +F+ R
Sbjct: 670 LHQTHPHFIRCIIPNELKKAGMIDANLVLNQLTCNGVLEGIRICRKGFPNRMPFLDFKQR 729
Query: 2179 YEILTPDVIPKNFIDGKESVRKMITALDIDTNL----YRIGQSKVFFRTGVLAHLEEERD 2346
Y +L D K D K++ K+ AL D +L ++ G +KVFF+ GVLAHLEE RD
Sbjct: 730 YAVLAADA-AKAGKDPKDAGEKISAALIKDGSLKQEEFQCGLTKVFFKAGVLAHLEELRD 788
Query: 2347 LKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKP 2526
L ++ FQ CR +L++ Y N A+ LR+W W++LF +VKP
Sbjct: 789 EALGKIMAKFQCACRHYLAQCEYKRKLDQKVGLIVLQRNIRAWCTLRSWSWFKLFGRVKP 848
Query: 2527 LLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENS 2706
L++ ++ ++E A + + + +E + E ++ E + ++ E+ + QL+QE ++S
Sbjct: 849 LIKGSKKNEEFEALEKKFKVLEEEKTQEERKRKDMEAENARLEAEKQALLIQLEQERDSS 908
Query: 2707 AELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXX 2886
AE ++ +L + +LE + +M D+L ++K +
Sbjct: 909 AEGEERSAKLLAQKADLEKQMANMNDQLCDEEEKNAALTKQKKKIEQDNEGLKKTVSDLE 968
Query: 2887 XXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAK 3066
+K D + L + E++
Sbjct: 969 TTIKKQESEKQAKDHQIRSLQDEIQSQDEVISKLNKEKKHQEEVNRKLLEDIQAEEDKVN 1028
Query: 3067 HGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNN 3246
H K K +LE+ L ELE L RE++ + + E+ +RK+ EL+ +++ + E E
Sbjct: 1029 HLNKTKAKLESTLDELEDTLEREKRGRQDCEKQRRKVEGELKIAQELIEELNRHKHEQEQ 1088
Query: 3247 QLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRRE 3426
+ K+D EL +R ++E + V +Q+Q++++ I EL E+++ ERN+R+KAE R E
Sbjct: 1089 VIKKKDIELSSIQSRLEDEQSLVAKLQRQIKELLARIQELEEELDAERNSRSKAEKARNE 1148
Query: 3427 VVAQLEKVKGDVLDKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFS 3603
+ +LE++ GD LD+ AT Q +L +++ E+ ++ +E E + + K +
Sbjct: 1149 MQMELEEL-GDRLDEAGGATQAQIELNKKREAELAKLRQDLEDAAINSETSMAALRKKHN 1207
Query: 3604 RQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLM 3783
V EL DQ++ +K R +LE+++N +E ++ Q + R + ++ K EA L
Sbjct: 1208 DAVAELSDQLDTIQKMRGKLEREKNDKQREVDELQQSADVEAKQRQNCERMAKQLEAQLT 1267
Query: 3784 EIQANLAESDEHKRTLIDQLERSRDELDH----LNRVREEEEHAFANMQRRLATAXXXXX 3951
++ +SDE R LI +L ++++ + LNR E+ E + R
Sbjct: 1268 DM---TLKSDEQAR-LIQELTMGKNKVHNENQDLNRQLEDAEAQLCALNRIKQQQHSQLE 1323
Query: 3952 XXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARR 4131
TR + + ++ + E + EE + + +++++ A + R
Sbjct: 1324 ELKRTLDQETRERQSLHSQVSNYQLECEQFRESLEEEQDAKTDVQRQLSKANSEIQQWRA 1383
Query: 4132 KAE-ESVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
K E E V+ ++LEE R+K V+ +Q+QLE + + ++K+++ +LED+ ++ +
Sbjct: 1384 KFEGEGVSRAEELEETRRKLTHKVQEMQEQLENANQKIGTLEKNKQRLAHDLEDAQVDAD 1443
Query: 4303 NVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKE 4482
+ EK+QK F+ + E R + + + + +E R T L N+++ E
Sbjct: 1444 RANSIASSLEKKQKGFDKVLDEWRRKCEALVAEVEQSQRETRAAATETFRLRNQLEESGE 1503
Query: 4483 HLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQI 4662
E R ++L QEL+D + GK+VH+L+K +R LE E +++ ++E E L+
Sbjct: 1504 QTEAVKRENKALAQELKDIADQLGEGGKSVHDLQKMRRRLEIEKEELQQALDEAECALEA 1563
Query: 4663 AEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVS 4842
E +R ++ ++SE ++ + K+ E E R+ + I ++ LE E RG++ +
Sbjct: 1564 EEAKVMRAQIEVSQIRSEIEKRLQEKEEEFENTRKNHSRTIESMQVSLETESRGRAELLK 1623
Query: 4843 HRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLRE 5022
+KK+E + ELE L+ +N+L + E Q + EE +++ +
Sbjct: 1624 TKKKLEGDVNELEIALDHSNKLNVDGQKSMKKLQDTIRELQYQVEEEQRSLSESRDHANL 1683
Query: 5023 ADRKFRAVEAEREQLREANEGLMQARKQX---XXXXXXXXXXRAKGGGISSEEKRRLEAK 5193
A+R+ + ++ E+E L E + R+Q + + KR++E
Sbjct: 1684 AERRSQVLQQEKEDLAIIYEQSERTRRQAELELAEVKDSVNELSNSNSLLLATKRKVEGD 1743
Query: 5194 IAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDY 5373
+ S+ + + +K +KA + ++ +L E+ K++LE +D
Sbjct: 1744 LQLLQSEIEEAMSDAKTSDEKAKKAIMDASKLADELRSEQEHASNLNQSKKTLESQVKDL 1803
Query: 5374 KAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQ 5553
+ ++ E E+ + Q+A L+ ++ LE +L E + + R +++ + Q
Sbjct: 1804 QMRLDEAEAAGIKGGKRQLAKLDMRIHELETELEGENRRHAETQKVLRNKDRKCRELQFQ 1863
Query: 5554 FEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQ---READDLLDAN 5724
+++K++ E+ +L+EK K + +RQ+++AE S K+R +Q +A + DA
Sbjct: 1864 VDEDKKSQERMYDLIEKLQQKIKTYKRQIEDAESLASGNLAKYRQLQHVVEDAQERADAA 1923
Query: 5725 EQLTREL 5745
E ++L
Sbjct: 1924 ENALQKL 1930
Score = 70.1 bits (170), Expect = 6e-10
Identities = 97/418 (23%), Positives = 179/418 (42%), Gaps = 27/418 (6%)
Frame = +1
Query: 4579 LEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEE 4758
LEK + LE E + +++E AE+ARL E ++ E +R + E EE
Sbjct: 862 LEKKFKVLEEEKTQEERKRKDME-----AENARLEAEKQALLIQLEQER---DSSAEGEE 913
Query: 4759 KRRGLLKQIRDLENELEN-------EKRGKSGAVSHRKKIENQIGELEQQL-EVANRLKE 4914
+ LL Q DLE ++ N E+ + +KKIE L++ + ++ +K+
Sbjct: 914 RSAKLLAQKADLEKQMANMNDQLCDEEEKNAALTKQKKKIEQDNEGLKKTVSDLETTIKK 973
Query: 4915 EYXXXXXXXXXXXXEYQIEC-EEARQAKEDIAALLR-------EADRKF-RAVEAEREQL 5067
+ ++QI ++ Q+++++ + L E +RK ++AE +++
Sbjct: 974 Q------ESEKQAKDHQIRSLQDEIQSQDEVISKLNKEKKHQEEVNRKLLEDIQAEEDKV 1027
Query: 5068 REANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRL---EAKIAQXXXXXXXXQSNC 5238
N+ +A+ + R K G E++RR E KIAQ +
Sbjct: 1028 NHLNK--TKAKLESTLDELEDTLEREKRGRQDCEKQRRKVEGELKIAQELIEELNRHKHE 1085
Query: 5239 ELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELE----SGA 5406
+ + K K ++L I + L E++L K L+R ++ A+I ELE +
Sbjct: 1086 QEQVIK--KKDIELSSIQSRLEDEQSLVAK-------LQRQIKELLARIQELEEELDAER 1136
Query: 5407 QSRARAQMAA--LEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANE 5580
SR++A+ A ++ +++ L D+L+ G A ++ E L Q ED +E
Sbjct: 1137 NSRSKAEKARNEMQMELEELGDRLDEAGGATQAQIELNKKREAELAKLRQDLEDAAINSE 1196
Query: 5581 QAKELLEKS-NLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
+ L K N L QLD + + + + QRE D+L + + ++ N
Sbjct: 1197 TSMAALRKKHNDAVAELSDQLDTIQKMRGKLEREKNDKQREVDELQQSADVEAKQRQN 1254
Score = 43.9 bits (102), Expect = 0.047
Identities = 35/177 (19%), Positives = 84/177 (46%), Gaps = 8/177 (4%)
Frame = +1
Query: 3052 EERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAE----- 3216
+E+AK + +L ++L E+++ S L Q K+ L ++++D + L E
Sbjct: 1762 DEKAKKAIMDASKLADELRS-------EQEHASNLNQSKKTLESQVKDLQMRLDEAEAAG 1814
Query: 3217 -KMGK--VEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETE 3387
K GK + +L+ ++ + + EL+ + R+ E + ++ R++Q +DE ++ E
Sbjct: 1815 IKGGKRQLAKLDMRIHELETELEGENRRHAETQKVLRNKDRKCRELQFQVDEDKKSQERM 1874
Query: 3388 RNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQ 3558
+ K + + Q+E + + + LQ ++ E +A + A+++++
Sbjct: 1875 YDLIEKLQQKIKTYKRQIEDAESLASGNLAKYRQLQHVVEDAQERADAAENALQKLR 1931
>gi|11276955|pir||A59236 embryonic muscle myosin heavy chain - sea
squirt (Halocynthia roretzi)
gi|1197168|dbj|BAA08111.1| embryonic muscle myosin heavy chain
[Halocynthia roretzi]
Length = 1927
Score = 1108 bits (2867), Expect = 0.0
Identities = 638/1903 (33%), Positives = 1056/1903 (54%), Gaps = 25/1903 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K WVP++ + ++ G + + ++ D ++VT+ DD+Q NPP+++K EDM
Sbjct: 34 KKYVWVPNKEKAYIKGEVISIEGGKAKLKTCDEGKEVTVKEDDLQLMNPPRYNKCEDMVN 93
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
+T+LNEASVL NL DRY + +IYTYSGLFCV +NPYK LP+Y+ +I+ ++GK++ EMPP
Sbjct: 94 MTHLNEASVLRNLNDRYTAFMIYTYSGLFCVTVNPYKMLPVYAPYVIQAYRGKRKTEMPP 153
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
H+++IAD AY ML RE+QS+L TGESGAGKT NTKKVIQY A V AA
Sbjct: 154 HLYSIADNAYTEMLMNRENQSMLITGESGAGKTVNTKKVIQYFALV-----------AAD 202
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
++ Q D G LE Q++Q NP +EAFGN+KT +NDNSSRFGKFIRI+F +G ++
Sbjct: 203 NSVAQNDDK----GTLEDQIVQCNPAMEAFGNAKTARNDNSSRFGKFIRIHFGATGSLAS 258
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRF-LVNRG-IT 969
+IE YLLEKSRV+ Q ER++HIFYQI+ G E + LL D Y F +++G +
Sbjct: 259 GDIEHYLLEKSRVIWQQAGERNYHIFYQIISG-GKPELIDQLLVTKDPYDFKSISQGVVV 317
Query: 970 LPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDR 1149
+ N+DD QE T + I+GF +EI+ I R+++ ++ N++F +++ +QA
Sbjct: 318 VENLDDAQELLLTDEAFHILGFTQEEINGIYRIMAGIMHQQNMKFKNKQREEQAEPDGTE 377
Query: 1150 VIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWL 1329
KV +L G+ + K PR+KVG EFV K Q Q +++ ++K +E+ F WL
Sbjct: 378 DADKVAYLFGMNSADFLKYICHPRVKVGNEFVTKGQTVPQVTYSIGGLSKGIFEKHFNWL 437
Query: 1330 VTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQ 1509
V IN+SL T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF+LEQ
Sbjct: 438 VKIINQSLS-TKLPRSYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQ 496
Query: 1510 EEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-N 1686
EEY++EGI+W FIDFG+DL I+LIEKP+G++++L+EEC+FPKA D SF EKL + H
Sbjct: 497 EEYKKEGIDWVFIDFGMDLAACIELIEKPLGIMSILEEECMFPKATDNSFKEKLYQNHLG 556
Query: 1687 KHPKFIVPDMRSK--SHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAG 1860
K F P ++K +HF + HYAG V YS WL KN +PLN +VV L + + +
Sbjct: 557 KTKAFGKPVKKTKFEAHFELHHYAGTVAYSVTDWLEKNKEPLNNSVVELYKKCSLKLMQT 616
Query: 1861 IWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIP 2040
IW+ F A G R + G F TVS +H+E L KLMT LR+T+PHFVRCI+P
Sbjct: 617 IWEG--FVSADDASSGGGKGGKRKKGGSFMTVSSMHRESLNKLMTNLRSTAPHFVRCIVP 674
Query: 2041 NHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NF 2217
N K G+++ ++VL QLRCNGVLEGIRICR+GFPNR+P+ +F+ RY IL P+ +P+ F
Sbjct: 675 NDTKTPGEMDPHIVLHQLRCNGVLEGIRICRKGFPNRLPYGDFKQRYRILNPNAVPEGQF 734
Query: 2218 IDGKESVRKMITALD-IDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRG 2394
+D K+ K++++L+ ID Y++G +KVFFR G+L LEE RD KL+++ QA+ RG
Sbjct: 735 VDSKKGSEKILSSLETIDHTQYKLGHTKVFFRAGMLGVLEELRDDKLSSIFKLIQARLRG 794
Query: 2395 FLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQ---VTRTDDEIRA 2565
L + Y N A+ +R+W+W +L K+KPLLQ + +++ A
Sbjct: 795 KLMKIEYNKLIEQRVAVRVIQSNLRAFFGVRDWEWMKLMFKIKPLLQTAEAAKEMEQLEA 854
Query: 2566 KDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTR 2745
+++EL+ E+ +K + E++ L I E+ + QLQ E + + +D +L
Sbjct: 855 ENEELKTNYEKEMKRRKELEESQVSL---IQEKNDLLMQLQSEQDRIEDAEDRCDQLIRT 911
Query: 2746 NQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNV 2925
EL+ + ++++RL +RK + + +K
Sbjct: 912 KVELDGKIKEIQERLEDEEELNNELVSKKRKLEDECSELKKDIDDLEITLAKVEKEKHAT 971
Query: 2926 DQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQL 3105
+ + L E++A K K +LE Q+
Sbjct: 972 ENKLKNLQEELASQDEQIAKLQKEKKALQEAHQQTLDDLQSEEDKANSLTKQKAKLEQQV 1031
Query: 3106 HELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQL 3285
+LE L +E++ + +LE+ KRKL +L +++ + + + L +L K++ E
Sbjct: 1032 DDLEASLEQEKKLRMDLERTKRKLEGDLRLTQETVMDLENDKQRLEEKLKKQEFEYSQLA 1091
Query: 3286 TRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVL 3465
T+ ++E A V +QK+++++Q I+EL E++E ER AR K E R ++ +LE++ + L
Sbjct: 1092 TKLEDEQALVMQLQKKIKELQARIEELEEELEAERAARAKVEKQRADLSRELEEL-SERL 1150
Query: 3466 DKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQH 3642
++ AT Q +L R++ E + +R +E+ E + + K + E+ +QI+
Sbjct: 1151 EEAGGATAAQIELNKRREAEFSKLRRELEESNLAHEATVSTLRKKHADSSAEMSEQIDNL 1210
Query: 3643 KKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHK 3822
++ + +LEK++++ E D+A + + ++ + +K + E E + +
Sbjct: 1211 QRVKQKLEKEKSEMKMEVDDLAANVESITKAKLNYEKMARNLEEQFSESKTKCDNFCKEV 1270
Query: 3823 RTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANI 4002
L R E L+R EE EH A + R ++ T+ K A
Sbjct: 1271 NELNAAKARFASENGELSRQLEEREHLMAQLTRTKNSSSQQIEELKRVVEEETKAKAALA 1330
Query: 4003 NRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESV---NQQLEELR 4173
+ + + + L ++ EE + +A L++ + A + R K E ++LEE +
Sbjct: 1331 HSVQASRHDNDLLREQYEEEQEAKAELQRALSKANAEVAQWRNKYETDAIQRTEELEEAK 1390
Query: 4174 KKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFE 4353
KK ++ ++Q+E ++ + ++K ++Q ELED +++LE ++ +K+Q+ F+
Sbjct: 1391 KKLATRLQEAEEQVEATQAKCASLDKTKNRLQGELEDLTIDLERSNSAAAALDKKQRNFD 1450
Query: 4354 SQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQ 4533
+AE + ++ ++ + +E R T + + N + + LE R ++LQ+E+
Sbjct: 1451 KVLAERKQKEEEIQVELEQAQKEARGLSTELFKMKNSYEESLDALETVKRENKNLQEEIA 1510
Query: 4534 DSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKS 4713
D + GK++HELEKAKR+LE E N+++ +EE E ++ E LRL+V +K
Sbjct: 1511 DLTDQLGEGGKSIHELEKAKRTLEHERNEIQAALEEAEGAIEGEESKVLRLQVELAQIKQ 1570
Query: 4714 ESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLE 4893
+ +R +S K+ E E RR + + ++ L++E + + AV +KK+E + +LE QL
Sbjct: 1571 DFERRLSEKEEEIENTRRNQQRALESMQTTLDSESKSRQEAVRMKKKMEGDLNDLEIQLG 1630
Query: 4894 VANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLRE 5073
A R E + +++ +E+++ +D+ +R+ ++AE ++LR
Sbjct: 1631 HATRQASESQKSVKTFQAHVKDLELQVDESQRHSDDLQEQFAVIERRENLIKAEIDELRS 1690
Query: 5074 ANEGLMQARK----QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCE 5241
A E + RK + + + + +KR+LE ++ QS E
Sbjct: 1691 ALEQAERGRKLAETELLESSERSNLLHTQNTALIN-QKRKLEGELQN-------VQSEVE 1742
Query: 5242 LAIDKQRKAQVQLEQITTDLSM-------ERTLNQKTEAEKQSLERSNRDYKAKITELES 5400
A+ +QR A+ + ++ TD +M E+ L+ E K++ E++ +D + ++ E E
Sbjct: 1743 EAVQEQRNAEEKAKKAITDAAMMAEELKKEQDLSSHLERMKKNTEQTVKDLQQRLDEAEQ 1802
Query: 5401 GAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANE 5580
A + Q+ LE +V+ LE++L+ E + + + R+ E++L + T Q E++K+
Sbjct: 1803 VALKGGKKQVQKLETRVRELENELDSEQRRNGESVKNQRKTERKLKEVTYQAEEDKKNLV 1862
Query: 5581 QAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+ ++L++K +K + +RQ +EAE++ ++ +K+R +Q E DD
Sbjct: 1863 RIQDLVDKLQIKVKTYKRQSEEAEEQANQNMSKYRKLQHELDD 1905
Score = 162 bits (411), Expect = 7e-38
Identities = 210/1030 (20%), Positives = 435/1030 (41%), Gaps = 39/1030 (3%)
Frame = +1
Query: 2569 DDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRN 2748
+ E AT+ +L ++ + ++++ ++ E+ +QE QQ ++ +D L +
Sbjct: 965 EKEKHATENKLKNLQEELASQDEQIAKLQKEKKALQEAHQQTLDDLQSEEDKANSLTKQK 1024
Query: 2749 QELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVD 2928
+LE V+D+ L +RK +R +T +D
Sbjct: 1025 AKLEQQVDDLEASLEQEKKLRMDLERTKRKLEGDLR----------------LTQETVMD 1068
Query: 2929 QXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLH 3108
+ ++ L T+L D + K L+ ++
Sbjct: 1069 LENDKQRLEEKLKKQEFEYSQ------------LATKLEDEQALVMQLQKKIKELQARIE 1116
Query: 3109 ELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLT 3288
ELE++L ER ++++E+ + L ELE+ + L E+ G +L KR E +L
Sbjct: 1117 ELEEELEAERAARAKVEKQRADLSRELEELSERL-EEAGGATAAQIELNKRREAEFSKLR 1175
Query: 3289 RYDEES-----ANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVK 3453
R EES A V+ ++K+ D E+ E ++ + + K E + E+ +++ +
Sbjct: 1176 RELEESNLAHEATVSTLRKKHADSSA---EMSEQIDNLQRVKQKLEKEKSEMKMEVDDLA 1232
Query: 3454 GDVLDKVDEATMLQDLMSRK-DEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
+V + + +A + + M+R +E+ + +K + + ++ KA+F+ + EL Q
Sbjct: 1233 ANV-ESITKAKLNYEKMARNLEEQFSESKTKCDNFCKEV-NELNAAKARFASENGELSRQ 1290
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIA-----------LLQASRADIDKKRKIHEAH 3777
+E+ + +QL + +N + Q+ ++ + + +QASR D D R+ +E
Sbjct: 1291 LEEREHLMAQLTRTKNSSSQQIEELKRVVEEETKAKAALAHSVQASRHDNDLLREQYEEE 1350
Query: 3778 LMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXX 3957
E +A L + + Q R++ E D + R E EE +++LAT
Sbjct: 1351 -QEAKAELQRALSKANAEVAQW-RNKYETDAIQRTEELEE-----AKKKLAT----RLQE 1399
Query: 3958 XXXXXXXTRLKIANINRAR-QLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRK 4134
T+ K A++++ + +L+ E L + E + A L+K+ + E R++
Sbjct: 1400 AEEQVEATQAKCASLDKTKNRLQGELEDLTIDLERSNSAAAALDKKQRNFDKVLAE-RKQ 1458
Query: 4135 AEESVNQQLEELRKKN---LRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELEN 4305
EE + +LE+ +K+ ++ ++ EES A E + + K +Q+E+ D + +L
Sbjct: 1459 KEEEIQVELEQAQKEARGLSTELFKMKNSYEESLDALETVKRENKNLQEEIADLTDQLGE 1518
Query: 4306 VRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMK-- 4479
S + EK ++ E + E + A+++A + E++VL L E+ +K
Sbjct: 1519 GGKSIHELEKAKRTLEHERNEIQAALEEA-------EGAIEGEESKVLRLQVELAQIKQD 1571
Query: 4480 ------EHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE 4641
E EE + RR+ Q+ L+ + D K+ E + K+ +E +LND+ +Q+
Sbjct: 1572 FERRLSEKEEEIENTRRNQQRALESMQTTLDSESKSRQEAVRMKKKMEGDLNDLEIQLGH 1631
Query: 4642 LEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAE-----EKRRGLLK-QIRDLENE 4803
++ + + + L+ + D + + D E E+R L+K +I +L +
Sbjct: 1632 ATRQASESQKSVKTFQAHVKDLELQVDESQRHSDDLQEQFAVIERRENLIKAEIDELRSA 1691
Query: 4804 LENEKRGKSGAVSHRKKIENQIGELEQQ----LEVANRLKEEYXXXXXXXXXXXXEYQIE 4971
LE +RG+ A + + + L Q + +L+ E E +
Sbjct: 1692 LEQAERGRKLAETELLESSERSNLLHTQNTALINQKRKLEGELQNVQSEVEEAVQEQRNA 1751
Query: 4972 CEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKG 5151
E+A++A D AA++ E +K + + + E++++ E Q K KG
Sbjct: 1752 EEKAKKAITD-AAMMAEELKKEQDLSSHLERMKKNTE---QTVKDLQQRLDEAEQVALKG 1807
Query: 5152 GGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKT 5331
G ++ ++LE ++ + Q ++ QRK + +L+++T ++ +
Sbjct: 1808 G---KKQVQKLETRVRELENELDSEQRRNGESVKNQRKTERKLKEVTYQAEEDKKNLVRI 1864
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRA 5511
+ L+ + YK + E E A +K + L+ +L+ + A A
Sbjct: 1865 QDLVDKLQIKVKTYKRQSEEAEEQANQNM--------SKYRKLQHELDDAEERADMAESA 1916
Query: 5512 ARRLEKRLND 5541
+L + D
Sbjct: 1917 FNKLRSKARD 1926
Score = 133 bits (335), Expect = 5e-29
Identities = 162/785 (20%), Positives = 306/785 (38%), Gaps = 75/785 (9%)
Frame = +1
Query: 3613 EELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQ------ASRADIDKKRKIH-E 3771
EEL E+ K+R +LE+ Q QE+ D+ ++ Q R D + K+ +
Sbjct: 857 EELKTNYEKEMKRRKELEESQVSLIQEKNDLLMQLQSEQDRIEDAEDRCDQLIRTKVELD 916
Query: 3772 AHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNR----------VREEEEHA----FA 3909
+ EIQ L + +E L+ + + DE L + E+E+HA
Sbjct: 917 GKIKEIQERLEDEEELNNELVSKKRKLEDECSELKKDIDDLEITLAKVEKEKHATENKLK 976
Query: 3910 NMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEK----EEAEGLRA 4077
N+Q LA+ ++ + ED+ N+L +K ++ + L A
Sbjct: 977 NLQEELASQDEQIAKLQKEKKALQEAHQQTLDDLQSEEDKANSLTKQKAKLEQQVDDLEA 1036
Query: 4078 HLEKEIHAARQGAGEARRKAE-------------ESVNQQLEELRKKNLRDVEHLQKQLE 4218
LE+E R +RK E E+ Q+LEE KK + L +LE
Sbjct: 1037 SLEQE-KKLRMDLERTKRKLEGDLRLTQETVMDLENDKQRLEEKLKKQEFEYSQLATKLE 1095
Query: 4219 ESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALL 4398
+ + ++ + K++Q +E+ ELE RA+ EK++ ++ E +++A
Sbjct: 1096 DEQALVMQLQKKIKELQARIEELEEELEAERAARAKVEKQRADLSRELEELSERLEEAGG 1155
Query: 4399 DRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKD-DFGKNVH 4575
A + + RE E ++ LEES+ + L+ ++ + + +
Sbjct: 1156 ATAAQIELNKRREA-------EFSKLRRELEESNLAHEATVSTLRKKHADSSAEMSEQID 1208
Query: 4576 ELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAE 4755
L++ K+ LE E ++M++++++L N++ A+L E + R + + E++
Sbjct: 1209 NLQRVKQKLEKEKSEMKMEVDDLAANVESITKAKLNYE--------KMARNLEEQFSESK 1260
Query: 4756 EKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXX 4935
K K++ +L + + + ++ GEL +QLE L +
Sbjct: 1261 TKCDNFCKEVNELN--------------AAKARFASENGELSRQLEEREHLMAQLTRTKN 1306
Query: 4936 XXXXXXXEYQIECEEARQAKEDIA----ALLREADRKFRAVEAEREQLREANEGLMQARK 5103
E + EE +AK +A A + D E E+E E L +A
Sbjct: 1307 SSSQQIEELKRVVEEETKAKAALAHSVQASRHDNDLLREQYEEEQEAKAELQRALSKANA 1366
Query: 5104 QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLE 5283
+ + E K++L ++ + Q+ C + + Q +LE
Sbjct: 1367 EVAQWRNKYETDAIQRTEELEEAKKKLATRLQEAEEQVEATQAKCASLDKTKNRLQGELE 1426
Query: 5284 QITTDLSMERTL------------------NQKTEAEKQSLERSNRDYKAKITEL----- 5394
+T DL + QK E + LE++ ++ + TEL
Sbjct: 1427 DLTIDLERSNSAAAALDKKQRNFDKVLAERKQKEEEIQVELEQAQKEARGLSTELFKMKN 1486
Query: 5395 ----ESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFED 5562
A + + L+ ++ L DQL G+ +A R LE N+ E+
Sbjct: 1487 SYEESLDALETVKRENKNLQEEIADLTDQLGEGGKSIHELEKAKRTLEHERNEIQAALEE 1546
Query: 5563 EKRA--NEQAKEL---LEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANE 5727
+ A E++K L +E + +K ++ R+L E E+E+ R + LD+
Sbjct: 1547 AEGAIEGEESKVLRLQVELAQIK-QDFERRLSEKEEEIENTRRNQQRALESMQTTLDSES 1605
Query: 5728 QLTRE 5742
+ +E
Sbjct: 1606 KSRQE 1610
Score = 87.4 bits (215), Expect = 4e-15
Identities = 106/536 (19%), Positives = 238/536 (43%), Gaps = 14/536 (2%)
Frame = +1
Query: 4180 NLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQ 4359
+L ++H Q +L ++V + + +EL D + R K K ++
Sbjct: 747 SLETIDHTQYKLGHTKVFFRAGMLG---VLEELRDDKLSSIFKLIQARLRGKLMKIEYNK 803
Query: 4360 MAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDS 4539
+ E+RVAV+ + A +RD E + L+ ++ + + E + + + L+ E ++
Sbjct: 804 LIEQRVAVRVIQSNLRAFFG-VRDWEW--MKLMFKIKPLLQTAEAAKEMEQ-LEAENEEL 859
Query: 4540 ISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSES 4719
+N + K ELE+++ SL E ND+ +Q++ +D ++ AED
Sbjct: 860 KTNYEKEMKRRKELEESQVSLIQEKNDLLMQLQSEQDRIEDAED--------------RC 905
Query: 4720 DRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
D+ I K VE + K I++++ LE+E+ + VS ++K+E++ EL++ ++
Sbjct: 906 DQLIRTK-VELDGK-------IKEIQERLEDEEELNNELVSKKRKLEDECSELKKDID-- 955
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREAN 5079
+ +I + + K L+ + + + + +L++
Sbjct: 956 -------------------DLEITLAKVEKEKHATENKLKNLQEELASQDEQIAKLQKEK 996
Query: 5080 EGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQ 5259
+ L +A +Q K + +++K +LE ++ + E +++++
Sbjct: 997 KALQEAHQQ---TLDDLQSEEDKANSL-TKQKAKLEQQV-----------DDLEASLEQE 1041
Query: 5260 RKAQVQLEQITTDLSMERTLNQKT----EAEKQSLERSNRDYKAKITEL------ESGAQ 5409
+K ++ LE+ L + L Q+T E +KQ LE + + + ++L E
Sbjct: 1042 KKLRMDLERTKRKLEGDLRLTQETVMDLENDKQRLEEKLKKQEFEYSQLATKLEDEQALV 1101
Query: 5410 SRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAK 5589
+ + ++ L+A+++ LE++L E + + L + L + +++ E+ A
Sbjct: 1102 MQLQKKIKELQARIEELEEELEAERAARAKVEKQRADLSRELEELSERLEEAGGATAAQI 1161
Query: 5590 ELLEKSNLKNRNLRRQLDEA----EDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
EL ++ + LRR+L+E+ E +S R KH + E + +D +++ ++L
Sbjct: 1162 ELNKRREAEFSKLRRELEESNLAHEATVSTLRKKHADSSAEMSEQIDNLQRVKQKL 1217
>gi|24584698|ref|NP_724002.1| CG17927-PJ [Drosophila melanogaster]
gi|22946662|gb|AAF53566.3| CG17927-PJ [Drosophila melanogaster]
Length = 1960
Score = 1108 bits (2865), Expect = 0.0
Identities = 675/1917 (35%), Positives = 1077/1917 (55%), Gaps = 32/1917 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K CW+PD+ EG+L+G IK D V V L + I + V+K NPPKF+KIEDM++
Sbjct: 35 KKSCWIPDEKEGYLLGEIKATKGDIVSVGLQGGEVR-DIKSEKVEKVNPPKFEKIEDMAD 93
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
+T LN VLHNL+ RYY+ LIYTYSGLFCV INPYK+ P+Y+ + ++GK+R+E+PP
Sbjct: 94 MTVLNTPCVLHNLRQRYYAKLIYTYSGLFCVAINPYKRYPVYTNRCAKMYRGKRRNEVPP 153
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIFAI+D AY ML +QS+L TGESGAGKTENTKKVI Y A V +K + AA+
Sbjct: 154 HIFAISDGAYVDMLTNHVNQSMLITGESGAGKTENTKKVIAYFATVGA---SKKTDEAAK 210
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
G LE Q++Q NP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++G
Sbjct: 211 SK-----------GSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFGPTGKLAG 259
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLL--EGVDNYRFLVNRGIT 969
A+IE YLLEK+RV+ Q ERS+HIFYQI+ G S EY L + +YR + T
Sbjct: 260 ADIETYLLEKARVISQQSLERSYHIFYQIMSG-SVPGVKEYCLLSNNIYDYRIVSQGKTT 318
Query: 970 LPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDR 1149
+P+V+D +E+ + I+GF E + R+ +AV+ +G ++F Q + +QA +
Sbjct: 319 IPSVNDGEEW--VAQAFDILGFTKQEKEDVYRITAAVMHMGGMKFKQRGREEQAEQDGEE 376
Query: 1150 VIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWL 1329
+V L G EL K L+PRIKVG EFV + +N +Q ++ A+ K ++RLFKWL
Sbjct: 377 EGGRVSKLFGCDTAELYKNLLKPRIKVGNEFVTQGRNVQQVTNSIGALCKGVFDRLFKWL 436
Query: 1330 VTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQ 1509
V + N++LD T ++ FIG+LDIAGFEIF+ N FEQ+CIN+TNEKLQQ FN+ MF+LEQ
Sbjct: 437 VKKCNETLD-TQQKRQHFIGVLDIAGFEIFEYNGFEQLCINFTNEKLQQFFNHHMFVLEQ 495
Query: 1510 EEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-N 1686
EEY+REGI+W FIDFG+DL IDLIEKPMG+L++L+EE +FPKA D++F EKL TH
Sbjct: 496 EEYKREGIDWAFIDFGMDLLACIDLIEKPMGILSILEEESMFPKATDQTFSEKLTNTHLG 555
Query: 1687 KHPKFIVPDM----RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFV 1854
K F P + +HFA+ HYAG V Y+ WL KN DPLN+ VV + S + +
Sbjct: 556 KSAPFQKPKPPKPGQQAAHFAIAHYAGCVSYNITGWLEKNKDPLNDTVVDQFKKSQNKLL 615
Query: 1855 AGIWKDAEFAGICAAEMNETAFGMRSRK-GMFRTVSQLHKEQLTKLMTTLRNTSPHFVRC 2031
I+ A+ AG E A G R +K G F TVS +KEQL LMTTLR+T PHFVRC
Sbjct: 616 IEIF--ADHAGQSGG--GEQAKGGRGKKGGGFATVSSAYKEQLNSLMTTLRSTQPHFVRC 671
Query: 2032 IIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK 2211
IIPN K+ G ++++LV+ QL CNGVLEGIRICR+GFPNR+ + +F+ RY+I+ P ++ +
Sbjct: 672 IIPNEMKQPGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKMRYKIMCPKLL-Q 730
Query: 2212 NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCR 2391
K++ +I +D+ + YR+G +KVFFR GVL +EE RD +L ++ QA R
Sbjct: 731 GVEKDKKATEIIIKFIDLPEDQYRLGNTKVFFRAGVLGQMEEFRDERLGKIMSWMQAWAR 790
Query: 2392 GFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKD 2571
G+LSR+ + N YL+LR W W++L+ KVKPLL V+R +DEI A+
Sbjct: 791 GYLSRKGFKKLQEQRVALKVVQRNLRKYLQLRTWPWYKLWQKVKPLLNVSRIEDEI-ARL 849
Query: 2572 DELRATKERLLKMEHDFRENEKKLD-QVIVERAVIQEQLQQESENSAELDDIRGRLQTRN 2748
+E E L E R+ + L+ +++ E+ + + L E + + +L +
Sbjct: 850 EEKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQDYQERNAKLTAQK 909
Query: 2749 QELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVD 2928
+LE + D+++RL+ ++K + + DK D
Sbjct: 910 NDLENQLRDIQERLTQEEDARNQLFQQKKKADQEISGLKKDIEDLELNVQKAEQDKATKD 969
Query: 2929 QXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLH 3108
+ + +L E++ H K K +LE L
Sbjct: 970 HQIRNLNDEIAHQDELINKLNKEKKMQGETNQKTGEELQAAEDKINHLNKVKAKLEQTLD 1029
Query: 3109 ELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLT 3288
ELE L RE++ + ++E+ KRK+ +L+ +++ +A+ +EL + ++D+EL
Sbjct: 1030 ELEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVADLERNKKELEQTIQRKDKELSSITA 1089
Query: 3289 RYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLD 3468
+ ++E V Q+Q++++Q I+EL E++E ER AR KAE R ++ +LE++ G+ L+
Sbjct: 1090 KLEDEQVVVLKHQRQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEEL-GERLE 1148
Query: 3469 KVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHK 3645
+ AT Q +L +++ E++ +R +E+ E + + K + V E+ +Q++Q
Sbjct: 1149 EAGGATSAQIELNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLN 1208
Query: 3646 KQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKR 3825
K +++ EK++N+ + D+ + + +A +K K + L E+Q+ L DE R
Sbjct: 1209 KLKAKAEKEKNEYYGQLNDLRAGVDHITNEKAAQEKIAKQLQHTLNEVQSKL---DETNR 1265
Query: 3826 TLIDQLERSRDEL----DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKI 3993
TL D + S+ +L L R EE E + + + + +R +
Sbjct: 1266 TLND-FDASKKKLSIENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERA 1324
Query: 3994 ANINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHAARQGAGEARRKAEE---SVNQQL 4161
+ + R LE + + L ++ +EEAEG +A L++++ A A R K E + +++L
Sbjct: 1325 TLLGKFRNLEHDLDNLREQVEEEAEG-KADLQRQLSKANAEAQVWRSKYESDGVARSEEL 1383
Query: 4162 EELRKKNLRDVEHLQKQLEESEVAKERILQ-------SKKKIQQELEDSSMELENVRASH 4320
EE ++K LQ +L E+E E + Q +K+++ E+ED +E++ A
Sbjct: 1384 EEAKRK-------LQARLAEAEETIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIA 1436
Query: 4321 RDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESD 4500
+EK+QK F+ + E ++ V + DA +E R+ T + L + +E LE
Sbjct: 1437 NAAEKKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVR 1496
Query: 4501 RVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARL 4680
R ++L E++D + + G+N+HE+EKA++ LEAE ++++ +EE E L+ E+ L
Sbjct: 1497 RENKNLADEVKDLLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVL 1556
Query: 4681 RLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIE 4860
R ++ ++ E DR I K+ E E R+ + + ++ LE E +GK+ A+ +KK+E
Sbjct: 1557 RAQLELSQVRQEIDRRIQEKEEEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLE 1616
Query: 4861 NQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFR 5040
I ELE L+ AN+ E + Q EE ++A++D L ++R+
Sbjct: 1617 ADINELEIALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRAN 1676
Query: 5041 AVEAEREQ----LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXX 5208
A++ E E+ L +A+ G QA ++ A+ IS+ KR+LE+++
Sbjct: 1677 ALQNELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISA-AKRKLESELQTLH 1735
Query: 5209 XXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKIT 5388
+ + + +K +KA V ++ +L E+ Q E +++LE+ ++ + ++
Sbjct: 1736 SDLDELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLD 1795
Query: 5389 ELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEK 5568
E E+ A + + LE +V+ LE++L+ E + A + R+ E+R+ + + Q E+++
Sbjct: 1796 EAEANALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDR 1855
Query: 5569 RANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQR---EADDLLDANEQ 5730
+ +E+ ++L++K K + +RQ++EAE+ + K R Q+ EA++ D EQ
Sbjct: 1856 KNHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQ 1912
Score = 155 bits (391), Expect = 1e-35
Identities = 179/950 (18%), Positives = 386/950 (39%), Gaps = 62/950 (6%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDE 3267
RLE + + E+ E + + ELE KLLAE D L+ + G +++
Sbjct: 848 RLEEKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQD---------- 897
Query: 3268 ELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEK 3447
Y E +A +T Q D++ + +++E + E +ARN+ +++ ++
Sbjct: 898 --------YQERNAKLTA---QKNDLENQLRDIQERLTQEEDARNQLFQQKKKADQEISG 946
Query: 3448 VKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+K D+ D + + KD ++ I Q + K+ ++K ++ +
Sbjct: 947 LKKDIEDLELNVQKAEQDKATKDHQIRNLNDEIAH-QDELINKLNKEKKMQGETNQKTGE 1005
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAE 3807
+++ + + + L K + + +Q ++ + + R D++K ++ E L Q +A+
Sbjct: 1006 ELQAAEDKINHLNKVKAKLEQTLDELEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVAD 1065
Query: 3808 SDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL 3987
+ +K+ L ++R EL + E+E+ QR++
Sbjct: 1066 LERNKKELEQTIQRKDKELSSITAKLEDEQVVVLKHQRQIKELQA--------------- 1110
Query: 3988 KIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEE 4167
R +LE+E A + +AE RA L +E+ + GE +A + + Q+E
Sbjct: 1111 ------RIEELEEEVEAERQARAKAEKQRADLAREL----EELGERLEEAGGATSAQIE- 1159
Query: 4168 LRKKNLRDVEHLQKQLEESEVAKERILQS-KKKIQQELEDSSMELENVRASHRDSEKRQK 4344
L KK ++ L++ LEE+ + E L + +KK + + + +++ + +EK +
Sbjct: 1160 LNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNKLKAKAEKEKN 1219
Query: 4345 KFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQ 4524
++ Q+ + R V ++ A + + + + + +++D L + D ++ L
Sbjct: 1220 EYYGQLNDLRAGVDHITNEKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSI 1279
Query: 4525 ELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE--------------LE---DN 4653
E D + ++ V +L K K SL +L D + +E LE DN
Sbjct: 1280 ENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERATLLGKFRNLEHDLDN 1339
Query: 4654 L--QIAEDARLRLEVTNQALKSESDRAISNKDVEA---------EEKRRGLLKQIRDLEN 4800
L Q+ E+A + ++ Q K+ ++ + E+ EE +R L ++ + E
Sbjct: 1340 LREQVEEEAEGKADLQRQLSKANAEAQVWRSKYESDGVARSEELEEAKRKLQARLAEAEE 1399
Query: 4801 ELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEE 4980
+E+ + G ++++ ++ +L+ +++ AN + E++++ ++
Sbjct: 1400 TIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIANAAEKKQKAFDKIIGEWKLKVDD 1459
Query: 4981 ARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGG-G 5157
+ R + ++ E+ +E E + + K +GG
Sbjct: 1460 LAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGRN 1519
Query: 5158 ISSEEK--RRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKT 5331
I EK +RLEA+ + ++ E +K +AQ++L Q+ ++ +R + +K
Sbjct: 1520 IHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEI--DRRIQEKE 1577
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRARA--QMAALEAKVQYLEDQLNVEGQEKTAAN 5505
E + + + R + LE+ A+ +A A LEA + LE L+ + A
Sbjct: 1578 EEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQ 1637
Query: 5506 RAARRLEKRLNDTTQQFEDEKR----------------------------ANEQAKELLE 5601
+ +R +++L D E+E+R EQA
Sbjct: 1638 KNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRR 1697
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
++ + + QL+E + + R ++ E L ++L E N
Sbjct: 1698 QAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDELLNEAKN 1747
Score = 82.4 bits (202), Expect = 1e-13
Identities = 82/418 (19%), Positives = 183/418 (43%), Gaps = 25/418 (5%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L +Q+ E ++++ + + LE K +L A LE+++ L ++ KV +L + +E
Sbjct: 1509 LLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQE 1568
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ ++ +EE N ++ Q +D ++ +E E + +A ++++ A + ++
Sbjct: 1569 IDRRIQEKEEEFENTR------KNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINEL 1622
Query: 3451 KGDVLDKVDEATM-LQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+ LD ++A Q + R +++ + A+E+ Q + EQ R+ L +
Sbjct: 1623 E-IALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDA-REQLGISERRANALQN 1680
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL-- 3801
++E+ + Q ++ + QA+QE AD +++ + A A I ++ E+ L + ++L
Sbjct: 1681 ELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDE 1740
Query: 3802 ----AESDEHKRT--------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
A++ E K L D+L +D ++R+ E +Q RL A
Sbjct: 1741 LLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAEAN 1800
Query: 3946 XXXXXXXXXXXTRLKIANIN------RARQLEDEKNALLDEKEEAE-GLRAHLEKEIHAA 4104
++ + + R + +KN E+ E ++ +++ H
Sbjct: 1801 ALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRKNHER 1860
Query: 4105 RQGAGEARRKAEESVNQQLEELRK---KNLRDVEHLQKQLEESEVAKERILQSKKKIQ 4269
Q + ++ ++ +Q+EE + NL Q++LEE+E + Q+ K +
Sbjct: 1861 MQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQAISKFR 1918
>gi|3041707|sp|P13535|MYH8_HUMAN Myosin heavy chain, skeletal muscle,
perinatal (MyHC-perinatal)
Length = 1937
Score = 1107 bits (2863), Expect = 0.0
Identities = 643/1889 (34%), Positives = 1053/1889 (55%), Gaps = 15/1889 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V + E ++ +I+ + +V V+ + +T+ D V NPPK+DKIEDM+ +T+L
Sbjct: 41 FVAEPKESYVKSTIQSKEGGKVTVK-TEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHL 99
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y +++ ++GKKR E PPHIF+
Sbjct: 100 HEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFS 159
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A K + Q
Sbjct: 160 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKDESGKMQ--- 216
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 217 ---------GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIE 267
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPNV 981
YLLEKSRV Q + ERS+HIFYQI + E LL + +Y F+ IT+P++
Sbjct: 268 TYLLEKSRVTFQLKAERSYHIFYQITSN-KKPDLIEMLLITTNPYDYAFVSQGEITVPSI 326
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
DD +E +T +++ I+GF +E SI ++ AV+ GN++F Q+++ +QA V K
Sbjct: 327 DDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADK 386
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L L +L KA PR+KVG E+V K Q +Q AV A+AKA YE++F W+VTRI
Sbjct: 387 AAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRI 446
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 447 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW FIDFG+DL I+LIEKP+G+ ++L+EEC+FPKA D SF KL H K
Sbjct: 506 KEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSFKNKLYDQHLGKSAN 565
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P + ++++HF+++HYAG VDY+ WL KN DPLN+ VVGL Q S +A +
Sbjct: 566 FQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASL-- 623
Query: 1870 DAEFAGICAAEMNETA-FGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNH 2046
F+ +AE + +A G + + F+TVS L +E L KLMT LR+T PHFVRCIIPN
Sbjct: 624 ---FSTYASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNE 680
Query: 2047 EKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFID 2223
K G + LVL QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L IP+ FID
Sbjct: 681 TKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQFID 740
Query: 2224 GKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLS 2403
K++ K++ ++DID Y+ G +KVFF+ G+L LEE RD KL +I QA CRGFL
Sbjct: 741 SKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFLM 800
Query: 2404 RRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELR 2583
R Y N A++ +++W W +LF K+KPLL+ T+ E+ +E +
Sbjct: 801 RVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQ 860
Query: 2584 ATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEY 2763
TK+ L K E +E E+K+ ++ E+ +Q Q+Q E+++ A+ ++ +L +LE
Sbjct: 861 KTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEA 920
Query: 2764 IVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXX 2943
+ ++ +R +RK + + +K +
Sbjct: 921 KIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 980
Query: 2944 XXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQD 3123
+ L E++ KAK +LE Q+ +LE
Sbjct: 981 LTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGS 1040
Query: 3124 LNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEE 3303
L +E++ + +LE+ KRKL +L+ +++ + ++L+ +L K++ E+ + +++ ++E
Sbjct: 1041 LEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDE 1100
Query: 3304 SANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEA 3483
A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L++ A
Sbjct: 1101 QAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEI-SERLEEAGGA 1159
Query: 3484 TMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQ 3660
T Q +L +++ E +R +E+ E + + K + + EL +QI+ ++ + +
Sbjct: 1160 TSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQK 1219
Query: 3661 LEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQ 3840
LEK++++ E D++ + ++ +++K + E + E++ E L Q
Sbjct: 1220 LEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQ 1279
Query: 3841 LERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQL 4020
R + E +R +E++ + + R + T+ K A + +
Sbjct: 1280 RARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSS 1339
Query: 4021 EDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEH 4200
+ + L ++ EE + +A L++ + A + R K E Q+ EEL + + +
Sbjct: 1340 RHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1399
Query: 4201 LQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEE 4371
LQ+ E E + + ++K+++Q E+ED +++E A+ +K+Q+ F+ ++E
Sbjct: 1400 LQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEW 1459
Query: 4372 RVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNK 4551
+ ++ + +A +E R T + + N + + LE R ++LQQE+ D
Sbjct: 1460 KQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQI 1519
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAI 4731
+ GK +HELEK K+ +E E +++ +EE E +L+ E LR+++ +KSE DR I
Sbjct: 1520 AEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKI 1579
Query: 4732 SNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLK 4911
+ KD E ++ +R + + +++ L+ E R ++ A+ +KK+E + E+E QL ANRL
Sbjct: 1580 AEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLA 1639
Query: 4912 EEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLM 5091
E E Q+ ++A + +ED+ L +R+ ++AE E+L E
Sbjct: 1640 AESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTE 1699
Query: 5092 QARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQR 5262
++RK Q K++LE ++Q A +K +
Sbjct: 1700 RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAK 1759
Query: 5263 KAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALE 5442
KA + +L E+ + E K++LE++ +D + ++ E E A + Q+ LE
Sbjct: 1760 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1819
Query: 5443 AKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNR 5622
A+V+ LE ++ E + A + R+ E+R+ + T Q E++++ + ++L++K K +
Sbjct: 1820 ARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVK 1879
Query: 5623 NLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+ +RQ +EAE++ + +K R +Q E ++
Sbjct: 1880 SYKRQAEEAEEQSNANLSKFRKLQHELEE 1908
Score = 170 bits (430), Expect = 4e-40
Identities = 190/959 (19%), Positives = 418/959 (42%), Gaps = 61/959 (6%)
Frame = +1
Query: 3040 LLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKL-------------- 3177
L D EER + +K K +LE ++ E+ + E + +EL KRKL
Sbjct: 901 LADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDL 960
Query: 3178 ---LAELEDSK-------DHLAEKMGKVEELNNQLMKRDEELQ--HQLTRYD--EESANV 3315
LA++E K +L E+M ++E +L K + LQ HQ T D E V
Sbjct: 961 ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKV 1020
Query: 3316 TLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ 3495
++ K ++ +D+L +E E+ R E +R++ L+ + +D ++ L
Sbjct: 1021 NILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLD 1080
Query: 3496 DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQ 3675
+ + +K+ E++ IE + +E +++++ + ++EEL ++IE + R++ EKQ+
Sbjct: 1081 EKLEKKEFEISNLISKIED-EQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQR 1139
Query: 3676 NQADQERADMA---QEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLI---- 3834
+ +E +++ +E +++ +++KKR EA +++ +L E+ ++
Sbjct: 1140 SDLSRELEEISERLEEAGGATSAQVELNKKR---EAEFQKLRRDLEEATLQHEAMVAALR 1196
Query: 3835 ----DQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANI 4002
D + +++D+L RV+++ E + ++ ++
Sbjct: 1197 KKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKM----- 1251
Query: 4003 NRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEE--SVNQQLEELRK 4176
R LED+ + L ++EE + L L + + AGE R+ +E ++ QL ++
Sbjct: 1252 --CRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQ 1309
Query: 4177 KNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFES 4356
+ + +E L+ QLEE AK + + + + + + + E + + ++ K S
Sbjct: 1310 ASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANS 1369
Query: 4357 QMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLE-------ESDRVRRS 4515
++A+ R + + R ++EL + + ++ L E + EH+E ++ ++
Sbjct: 1370 EVAQWRTKYETDAIQR---TEELEEAKKKLAQRLQEAE---EHVEAVNAKCASLEKTKQR 1423
Query: 4516 LQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVT 4695
LQ E++D + + + L+K +R+ + L++ + + EE + L+ ++ L
Sbjct: 1424 LQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTE 1483
Query: 4696 NQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGE 4875
+K+ + ++ + E + L ++I DL ++ + +K++E + E
Sbjct: 1484 LFKVKNVYEESLDQLETLRRE-NKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCE 1542
Query: 4876 LEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEAR--QAKEDIAALLREADRKFRAVE 5049
++ LE A E +E EE + + + ++ + E DRK +
Sbjct: 1543 IQAALEEA-------------------EASLEHEEGKILRIQLELNQVKSEVDRKIAEKD 1583
Query: 5050 AEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQ 5229
E +QL+ + +++ + R++ + K+++E + +
Sbjct: 1584 EEIDQLKRNHTRVVETMQ-----STLDAEIRSRNDAL--RVKKKMEGDLNEMEIQLNHAN 1636
Query: 5230 SNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQ--SLERSNRDYKAKITE---- 5391
++ R Q L++ T L ++ L + + ++Q +ER +A+I E
Sbjct: 1637 RLAAESLRNYRNTQGILKE--TQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWAT 1694
Query: 5392 LESGAQSRARAQMAALEA--KVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDE 5565
LE +SR A+ L+A +VQ L Q T+ ++LE ++ + E+
Sbjct: 1695 LEQTERSRKIAEQELLDASERVQLLHTQ-------NTSLINTKKKLENDVSQLQSEVEEV 1747
Query: 5566 KRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL---LDANEQL 5733
+ + A+E +K+ + +L + +D + +N+++ DL LD EQL
Sbjct: 1748 IQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQL 1806
Score = 115 bits (289), Expect = 1e-23
Identities = 180/908 (19%), Positives = 357/908 (38%), Gaps = 131/908 (14%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ +E + ME+D ++ ++KL++ E + + ++ E E + E+ +LQ
Sbjct: 1056 RKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKI--EDEQAVEI-----QLQ 1108
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRR---KQMETVRDXXXXXXXXXXXXXXXXX 2910
+ +EL+ + ++ + + R +++E + +
Sbjct: 1109 KKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNK 1168
Query: 2911 DKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKG 3087
+ Q +A G + +D+ +R K + K K
Sbjct: 1169 KREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELG---EQIDNLQRVKQKLEKEKS 1225
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDE 3267
L+ + +L + + K LE K+ LED L K + + L N L +
Sbjct: 1226 ELKMETDDLSSNAEAISKAKGNLE----KMCRSLEDQVSELKTKEEEQQRLINDLTAQRA 1281
Query: 3268 ELQHQLTRY----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVA 3435
LQ + Y DE+ A V+ + + + I+EL+ +E E A+N +
Sbjct: 1282 RLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRH 1341
Query: 3436 QLEKVKGDVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQ 3609
+ ++ ++ + LQ +S+ + EV TK + IQ T E +EE K K +++
Sbjct: 1342 DCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQR 1399
Query: 3610 VEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME- 3786
++E + +E + + LEK + + E D+ ++ A+ A +DKK++ + L E
Sbjct: 1400 LQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEW 1459
Query: 3787 ------IQANLAESDEHKRTL--------------IDQLERSRDE--------------- 3861
QA L S + R+L +DQLE R E
Sbjct: 1460 KQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQI 1519
Query: 3862 ------LDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLE 4023
+ L +++++ E +Q L A R+++ +N+ +
Sbjct: 1520 AEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKIL---RIQL-ELNQVKSEV 1575
Query: 4024 DEKNALLDEKEE---------AEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRK 4176
D K A DE+ + E +++ L+ EI + R A ++K E +N+ +L
Sbjct: 1576 DRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRS-RNDALRVKKKMEGDLNEMEIQLNH 1634
Query: 4177 KN---------------------------LRDVEHLQKQL--------------EESEVA 4233
N LR E L++QL EE
Sbjct: 1635 ANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWAT 1694
Query: 4234 KERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAM 4413
E+ +S+K +QEL D+S ++ + + +KK E+ +++ + V++ +
Sbjct: 1695 LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVI------ 1748
Query: 4414 SQELRDRETRVLSLLNEVDIMKEHLEES-------DRVRRSLQQELQDSISNKDDFG--- 4563
QE R+ E + + + +M E L++ +R++++L+Q ++D D+
Sbjct: 1749 -QESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLA 1807
Query: 4564 -----KNVHELEKAKRSLEAELNDMRVQMEELEDNL------------QIAEDAR--LRL 4686
K + +LE R LE E+ + + + E L Q ED + LRL
Sbjct: 1808 LKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRL 1867
Query: 4687 EVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQ 4866
+ L+++ ++ + EAEE+ L + R L++ELE + A S K+ +
Sbjct: 1868 QDLVDKLQAKV-KSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVK 1926
Query: 4867 IGELEQQL 4890
E+ ++
Sbjct: 1927 SREVHTKI 1934
Score = 94.4 bits (233), Expect = 3e-17
Identities = 90/449 (20%), Positives = 192/449 (42%), Gaps = 20/449 (4%)
Frame = +1
Query: 3100 QLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQH 3279
Q+HELE+ K ++EQ K ++ A LE+++ L + GK+ + +L + E+
Sbjct: 1525 QIHELEK-------IKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1577
Query: 3280 QLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGD 3459
++ DEE + + R+ ++ ++ ++ E +RN A ++ K++GD
Sbjct: 1578 KIAEKDEE------IDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKK-------KMEGD 1624
Query: 3460 VLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKI------EEQKAKFSRQVEEL 3621
+ + + L + T+ +++ Q ++ + +EQ A R+ L
Sbjct: 1625 LNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLL 1684
Query: 3622 HDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL 3801
+IE+ Q E+ + A+QE D ++ + LL + +K E + ++Q+ +
Sbjct: 1685 QAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEV 1744
Query: 3802 AESDEHKRT--------------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAX 3939
E + R + ++L++ +D HL R+++ E ++Q RL A
Sbjct: 1745 EEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAE 1804
Query: 3940 XXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAG 4119
++ + + E ++NA E +GLR H E+ +
Sbjct: 1805 QLALKGGKKQIQKLEARVRELEGEVENEQKRNA-----EAVKGLRKH-ERRVKELTYQTE 1858
Query: 4120 EARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMEL 4299
E R+ +L++L K V+ ++Q EE+E L +K+Q ELE++
Sbjct: 1859 EDRKNV-----LRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEA---- 1909
Query: 4300 ENVRASHRDSEKRQKKFESQMAEERVAVQ 4386
RA +S+ + + +S+ +++ +
Sbjct: 1910 -EERADIAESQVNKLRVKSREVHTKISAE 1937
Score = 76.6 bits (187), Expect = 7e-12
Identities = 76/389 (19%), Positives = 169/389 (42%), Gaps = 25/389 (6%)
Frame = +1
Query: 4654 LQIAEDARLRLEVTNQALKSESDRAISN-KDVEAEEKRRGLLKQIRDLENELENEKRGKS 4830
L+ AE + + + K++ + A S K E EEK LLK+ DL+ ++++E +
Sbjct: 843 LKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLA 902
Query: 4831 GAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAA 5010
A +++ +LE +++ EE + + EC E ++ +D+
Sbjct: 903 DAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLEL 962
Query: 5011 LLREADRKFRAVEAEREQLREANEGL----------MQARKQXXXXXXXXXXXRAKGGGI 5160
L + +++ A E + + L E GL +A ++ I
Sbjct: 963 TLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNI 1022
Query: 5161 SSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLE----QITTDLSMERTLNQK 5328
++ K +LE ++ + E ++++++K ++ LE ++ DL + +
Sbjct: 1023 LTKAKTKLEQQV-----------DDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMD 1071
Query: 5329 TEAEKQSLERSNRDYKAKITEL------ESGAQSRARAQMAALEAKVQYLEDQLNVEGQE 5490
E +KQ L+ + +I+ L E + + + ++ L+A+++ L +++ E
Sbjct: 1072 MENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERAS 1131
Query: 5491 KTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEA----EDE 5658
+ A + L + L + +++ E+ A EL +K + + LRR L+EA E
Sbjct: 1132 RAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAM 1191
Query: 5659 MSRERTKHRNVQREADDLLDANEQLTREL 5745
++ R KH + E + +D +++ ++L
Sbjct: 1192 VAALRKKHADSMAELGEQIDNLQRVKQKL 1220
Score = 72.8 bits (177), Expect = 1e-10
Identities = 114/521 (21%), Positives = 203/521 (38%), Gaps = 18/521 (3%)
Frame = +1
Query: 4234 KERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAM 4413
K + L + ++E+ E + + SE ++K+ E +M L +
Sbjct: 838 KIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSE 897
Query: 4414 SQELRDRETRVLSLL-NEVDI------MKEHLEESDRV-------RRSLQQELQDSISNK 4551
+ L D E R L+ N++ + + E EE + + +R L+ E + +
Sbjct: 898 ADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDI 957
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQA----LKSES 4719
DD + ++EK K + E ++ ++ +M L++ + + L+ T+Q L++E
Sbjct: 958 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEE 1017
Query: 4720 DRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
D+ N +A+ K L +Q+ DLE LE EK+ R +E +LE L++A
Sbjct: 1018 DKV--NILTKAKTK---LEQQVDDLEGSLEQEKK-------LRMDLERAKRKLEGDLKLA 1065
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREAN 5079
+ + + E ED A+ + +K + ++A E+L E
Sbjct: 1066 QESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEI 1125
Query: 5080 EGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQ 5259
E RAK S+ R LE
Sbjct: 1126 EA--------------ERASRAKAEKQRSDLSRELE------------------------ 1147
Query: 5260 RKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAAL 5439
+ +LE+ S + LN+K EAE Q L R +LE A + A +AAL
Sbjct: 1148 -EISERLEEAGGATSAQVELNKKREAEFQKLRR----------DLEE-ATLQHEAMVAAL 1195
Query: 5440 EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKN 5619
K D + G++ R ++LEK ++ + D+ +N +A + K+
Sbjct: 1196 RKKHA---DSMAELGEQIDNLQRVKQKLEKEKSELKME-TDDLSSNAEA---ISKAK--- 1245
Query: 5620 RNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
NL + ED++S +TK QR +DL +L E
Sbjct: 1246 GNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTE 1286
>gi|2119300|pir||I38055 myosin heavy chain, perinatal skeletal muscle
- human
gi|558669|emb|CAA86293.1| Myosin [Homo sapiens]
Length = 1937
Score = 1107 bits (2863), Expect = 0.0
Identities = 643/1889 (34%), Positives = 1053/1889 (55%), Gaps = 15/1889 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V + E ++ +I+ + +V V+ + +T+ D V NPPK+DKIEDM+ +T+L
Sbjct: 41 FVAEPKESYVKSTIQSKEGGKVTVK-TEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHL 99
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y +++ ++GKKR E PPHIF+
Sbjct: 100 HEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFS 159
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A K + Q
Sbjct: 160 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKDESGKMQ--- 216
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 217 ---------GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIE 267
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPNV 981
YLLEKSRV Q + ERS+HIFYQI + E LL + +Y F+ IT+P++
Sbjct: 268 TYLLEKSRVTFQLKAERSYHIFYQITSN-KKPDLIEMLLITTNPYDYAFVSQGEITVPSI 326
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
DD +E +T +++ I+GF +E SI ++ AV+ GN++F Q+++ +QA V K
Sbjct: 327 DDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADK 386
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L L +L KA PR+KVG E+V K Q +Q AV A+AKA YE++F W+VTRI
Sbjct: 387 AAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRI 446
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 447 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW FIDFG+DL I+LIEKP+G+ ++L+EEC+FPKA D SF KL H K
Sbjct: 506 KEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSFKNKLYDQHLGKSAN 565
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P + ++++HF+++HYAG VDY+ WL KN DPLN+ VVGL Q S +A +
Sbjct: 566 FQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASL-- 623
Query: 1870 DAEFAGICAAEMNETA-FGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNH 2046
F+ +AE + +A G + + F+TVS L +E L KLMT LR+T PHFVRCIIPN
Sbjct: 624 ---FSTYASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNE 680
Query: 2047 EKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFID 2223
K G + LVL QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L IP+ FID
Sbjct: 681 TKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQFID 740
Query: 2224 GKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLS 2403
K++ K++ ++DID Y+ G +KVFF+ G+L LEE RD KL +I QA CRGFL
Sbjct: 741 SKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFLM 800
Query: 2404 RRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELR 2583
R Y N A++ +++W W +LF K+KPLL+ T+ E+ +E +
Sbjct: 801 RVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQ 860
Query: 2584 ATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEY 2763
TK+ L K E +E E+K+ ++ E+ +Q Q+Q E+++ A+ ++ +L +LE
Sbjct: 861 KTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEA 920
Query: 2764 IVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXX 2943
+ ++ +R +RK + + +K +
Sbjct: 921 KIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 980
Query: 2944 XXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQD 3123
+ L E++ KAK +LE Q+ +LE
Sbjct: 981 LTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGS 1040
Query: 3124 LNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEE 3303
L +E++ + +LE+ KRKL +L+ +++ + ++L+ +L K++ E+ + +++ ++E
Sbjct: 1041 LEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDE 1100
Query: 3304 SANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEA 3483
A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L++ A
Sbjct: 1101 QAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEI-SERLEEAGGA 1159
Query: 3484 TMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQ 3660
T Q +L +++ E +R +E+ E + + K + + EL +QI+ ++ + +
Sbjct: 1160 TSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQK 1219
Query: 3661 LEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQ 3840
LEK++++ E D++ + ++ +++K + E + E++ E L Q
Sbjct: 1220 LEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQ 1279
Query: 3841 LERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQL 4020
R + E +R +E++ + + R + T+ K A + +
Sbjct: 1280 RARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSS 1339
Query: 4021 EDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEH 4200
+ + L ++ EE + +A L++ + A + R K E Q+ EEL + + +
Sbjct: 1340 RHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1399
Query: 4201 LQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEE 4371
LQ+ E E + + ++K+++Q E+ED +++E A+ +K+Q+ F+ ++E
Sbjct: 1400 LQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEW 1459
Query: 4372 RVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNK 4551
+ ++ + +A +E R T + + N + + LE R ++LQQE+ D
Sbjct: 1460 KQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQI 1519
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAI 4731
+ GK +HELEK K+ +E E +++ +EE E +L+ E LR+++ +KSE DR I
Sbjct: 1520 AEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKI 1579
Query: 4732 SNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLK 4911
+ KD E ++ +R + + +++ L+ E R ++ A+ +KK+E + E+E QL ANRL
Sbjct: 1580 AEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLA 1639
Query: 4912 EEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLM 5091
E E Q+ ++A + +ED+ L +R+ ++AE E+L E
Sbjct: 1640 AESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTE 1699
Query: 5092 QARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQR 5262
++RK Q K++LE ++Q A +K +
Sbjct: 1700 RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAK 1759
Query: 5263 KAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALE 5442
KA + +L E+ + E K++LE++ +D + ++ E E A + Q+ LE
Sbjct: 1760 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1819
Query: 5443 AKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNR 5622
A+V+ LE ++ E + A + R+ E+R+ + T Q E++++ + ++L++K K +
Sbjct: 1820 ARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVK 1879
Query: 5623 NLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+ +RQ +EAE++ + +K R +Q E ++
Sbjct: 1880 SYKRQAEEAEEQSNANLSKFRKLQHELEE 1908
Score = 170 bits (430), Expect = 4e-40
Identities = 190/959 (19%), Positives = 418/959 (42%), Gaps = 61/959 (6%)
Frame = +1
Query: 3040 LLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKL-------------- 3177
L D EER + +K K +LE ++ E+ + E + +EL KRKL
Sbjct: 901 LADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDL 960
Query: 3178 ---LAELEDSK-------DHLAEKMGKVEELNNQLMKRDEELQ--HQLTRYD--EESANV 3315
LA++E K +L E+M ++E +L K + LQ HQ T D E V
Sbjct: 961 ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKV 1020
Query: 3316 TLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ 3495
++ K ++ +D+L +E E+ R E +R++ L+ + +D ++ L
Sbjct: 1021 NILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLD 1080
Query: 3496 DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQ 3675
+ + +K+ E++ IE + +E +++++ + ++EEL ++IE + R++ EKQ+
Sbjct: 1081 EKLEKKEFEISNLISKIED-EQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQR 1139
Query: 3676 NQADQERADMA---QEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLI---- 3834
+ +E +++ +E +++ +++KKR EA +++ +L E+ ++
Sbjct: 1140 SDLSRELEEISERLEEAGGATSAQVELNKKR---EAEFQKLRRDLEEATLQHEAMVAALR 1196
Query: 3835 ----DQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANI 4002
D + +++D+L RV+++ E + ++ ++
Sbjct: 1197 KKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKM----- 1251
Query: 4003 NRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEE--SVNQQLEELRK 4176
R LED+ + L ++EE + L L + + AGE R+ +E ++ QL ++
Sbjct: 1252 --CRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQ 1309
Query: 4177 KNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFES 4356
+ + +E L+ QLEE AK + + + + + + + E + + ++ K S
Sbjct: 1310 ASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANS 1369
Query: 4357 QMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLE-------ESDRVRRS 4515
++A+ R + + R ++EL + + ++ L E + EH+E ++ ++
Sbjct: 1370 EVAQWRTKYETDAIQR---TEELEEAKKKLAQRLQEAE---EHVEAVNAKCASLEKTKQR 1423
Query: 4516 LQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVT 4695
LQ E++D + + + L+K +R+ + L++ + + EE + L+ ++ L
Sbjct: 1424 LQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTE 1483
Query: 4696 NQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGE 4875
+K+ + ++ + E + L ++I DL ++ + +K++E + E
Sbjct: 1484 LFKVKNVYEESLDQLETLRRE-NKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCE 1542
Query: 4876 LEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEAR--QAKEDIAALLREADRKFRAVE 5049
++ LE A E +E EE + + + ++ + E DRK +
Sbjct: 1543 IQAALEEA-------------------EASLEHEEGKILRIQLELNQVKSEVDRKIAEKD 1583
Query: 5050 AEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQ 5229
E +QL+ + +++ + R++ + K+++E + +
Sbjct: 1584 EEIDQLKRNHTRVVETMQ-----STLDAEIRSRNDAL--RVKKKMEGDLNEMEIQLNHAN 1636
Query: 5230 SNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQ--SLERSNRDYKAKITE---- 5391
++ R Q L++ T L ++ L + + ++Q +ER +A+I E
Sbjct: 1637 RLAAESLRNYRNTQGILKE--TQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWAT 1694
Query: 5392 LESGAQSRARAQMAALEA--KVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDE 5565
LE +SR A+ L+A +VQ L Q T+ ++LE ++ + E+
Sbjct: 1695 LEQTERSRKIAEQELLDASERVQLLHTQ-------NTSLINTKKKLENDVSQLQSEVEEV 1747
Query: 5566 KRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL---LDANEQL 5733
+ + A+E +K+ + +L + +D + +N+++ DL LD EQL
Sbjct: 1748 IQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQL 1806
Score = 115 bits (288), Expect = 1e-23
Identities = 180/908 (19%), Positives = 357/908 (38%), Gaps = 131/908 (14%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ +E + ME+D ++ ++KL++ E + + ++ E E + E+ +LQ
Sbjct: 1056 RKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKI--EDEQAVEI-----QLQ 1108
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRR---KQMETVRDXXXXXXXXXXXXXXXXX 2910
+ +EL+ + ++ + + R +++E + +
Sbjct: 1109 KKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNK 1168
Query: 2911 DKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKG 3087
+ Q +A G + +D+ +R K + K K
Sbjct: 1169 KREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELG---EQIDNLQRVKQKLEKEKS 1225
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDE 3267
L+ + +L + + K LE K+ LED L K + + L N L +
Sbjct: 1226 ELKMETDDLSSNAEAISKAKGNLE----KMCRSLEDQVSELKTKEEEQQRLINDLTAQRA 1281
Query: 3268 ELQHQLTRY----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVA 3435
LQ + Y DE+ A V+ + + + I+EL+ +E E A+N +
Sbjct: 1282 RLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRH 1341
Query: 3436 QLEKVKGDVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQ 3609
+ ++ ++ + LQ +S+ + EV TK + IQ T E +EE K K +++
Sbjct: 1342 DCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQR 1399
Query: 3610 VEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME- 3786
++E + +E + + LEK + + E D+ ++ A+ A +DKK++ + L E
Sbjct: 1400 LQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEW 1459
Query: 3787 ------IQANLAESDEHKRTL--------------IDQLERSRDE--------------- 3861
QA L S + R+L +DQLE R E
Sbjct: 1460 KQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQI 1519
Query: 3862 ------LDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLE 4023
+ L +++++ E +Q L A R+++ +N+ +
Sbjct: 1520 AEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKIL---RIQL-ELNQVKSEV 1575
Query: 4024 DEKNALLDEKEE---------AEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRK 4176
D K A DE+ + E +++ L+ EI + R A ++K E +N+ +L
Sbjct: 1576 DRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRS-RNDALRVKKKMEGDLNEMEIQLNH 1634
Query: 4177 KN---------------------------LRDVEHLQKQL--------------EESEVA 4233
N LR E L++QL EE
Sbjct: 1635 ANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWAT 1694
Query: 4234 KERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAM 4413
E+ +S+K +QEL D+S ++ + + +KK E+ +++ + V++ +
Sbjct: 1695 LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVI------ 1748
Query: 4414 SQELRDRETRVLSLLNEVDIMKEHLEES-------DRVRRSLQQELQDSISNKDDFG--- 4563
QE R+ E + + + +M E L++ +R++++L+Q ++D D+
Sbjct: 1749 -QESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLA 1807
Query: 4564 -----KNVHELEKAKRSLEAELNDMRVQMEELEDNL------------QIAEDAR--LRL 4686
K + +LE R LE E+ + + + E L Q ED + LRL
Sbjct: 1808 LKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRL 1867
Query: 4687 EVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQ 4866
+ L+++ ++ + EAEE+ L + R L++ELE + A S K+ +
Sbjct: 1868 QDLVDKLQAKV-KSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERAHIAESQVNKLRVK 1926
Query: 4867 IGELEQQL 4890
E+ ++
Sbjct: 1927 SREVHTKI 1934
Score = 76.6 bits (187), Expect = 7e-12
Identities = 76/389 (19%), Positives = 169/389 (42%), Gaps = 25/389 (6%)
Frame = +1
Query: 4654 LQIAEDARLRLEVTNQALKSESDRAISN-KDVEAEEKRRGLLKQIRDLENELENEKRGKS 4830
L+ AE + + + K++ + A S K E EEK LLK+ DL+ ++++E +
Sbjct: 843 LKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLA 902
Query: 4831 GAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAA 5010
A +++ +LE +++ EE + + EC E ++ +D+
Sbjct: 903 DAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLEL 962
Query: 5011 LLREADRKFRAVEAEREQLREANEGL----------MQARKQXXXXXXXXXXXRAKGGGI 5160
L + +++ A E + + L E GL +A ++ I
Sbjct: 963 TLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNI 1022
Query: 5161 SSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLE----QITTDLSMERTLNQK 5328
++ K +LE ++ + E ++++++K ++ LE ++ DL + +
Sbjct: 1023 LTKAKTKLEQQV-----------DDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMD 1071
Query: 5329 TEAEKQSLERSNRDYKAKITEL------ESGAQSRARAQMAALEAKVQYLEDQLNVEGQE 5490
E +KQ L+ + +I+ L E + + + ++ L+A+++ L +++ E
Sbjct: 1072 MENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERAS 1131
Query: 5491 KTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEA----EDE 5658
+ A + L + L + +++ E+ A EL +K + + LRR L+EA E
Sbjct: 1132 RAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAM 1191
Query: 5659 MSRERTKHRNVQREADDLLDANEQLTREL 5745
++ R KH + E + +D +++ ++L
Sbjct: 1192 VAALRKKHADSMAELGEQIDNLQRVKQKL 1220
Score = 72.8 bits (177), Expect = 1e-10
Identities = 114/521 (21%), Positives = 203/521 (38%), Gaps = 18/521 (3%)
Frame = +1
Query: 4234 KERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAM 4413
K + L + ++E+ E + + SE ++K+ E +M L +
Sbjct: 838 KIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSE 897
Query: 4414 SQELRDRETRVLSLL-NEVDI------MKEHLEESDRV-------RRSLQQELQDSISNK 4551
+ L D E R L+ N++ + + E EE + + +R L+ E + +
Sbjct: 898 ADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDI 957
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQA----LKSES 4719
DD + ++EK K + E ++ ++ +M L++ + + L+ T+Q L++E
Sbjct: 958 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEE 1017
Query: 4720 DRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
D+ N +A+ K L +Q+ DLE LE EK+ R +E +LE L++A
Sbjct: 1018 DKV--NILTKAKTK---LEQQVDDLEGSLEQEKK-------LRMDLERAKRKLEGDLKLA 1065
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREAN 5079
+ + + E ED A+ + +K + ++A E+L E
Sbjct: 1066 QESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEI 1125
Query: 5080 EGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQ 5259
E RAK S+ R LE
Sbjct: 1126 EA--------------ERASRAKAEKQRSDLSRELE------------------------ 1147
Query: 5260 RKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAAL 5439
+ +LE+ S + LN+K EAE Q L R +LE A + A +AAL
Sbjct: 1148 -EISERLEEAGGATSAQVELNKKREAEFQKLRR----------DLEE-ATLQHEAMVAAL 1195
Query: 5440 EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKN 5619
K D + G++ R ++LEK ++ + D+ +N +A + K+
Sbjct: 1196 RKKHA---DSMAELGEQIDNLQRVKQKLEKEKSELKME-TDDLSSNAEA---ISKAK--- 1245
Query: 5620 RNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
NL + ED++S +TK QR +DL +L E
Sbjct: 1246 GNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTE 1286
>gi|86358|pir||A29320 myosin heavy chain, fast skeletal muscle,
embryonic [similarity] - chicken
Length = 1940
Score = 1107 bits (2863), Expect = 0.0
Identities = 645/1894 (34%), Positives = 1061/1894 (55%), Gaps = 20/1894 (1%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V E ++ +I+ + + +V V+ + +T+ D + NPPK+DKIEDM+ +T+L
Sbjct: 39 FVVHAKESYVKSTIQSKESGKVTVK-TEGGETLTVKEDQIFSMNPPKYDKIEDMAMMTHL 97
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 98 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVLAYRGKKRQEAPPHIFS 157
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A K
Sbjct: 158 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDKKK---------- 207
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
++ G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 208 EEQPAGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIE 267
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPNV 981
YLLEKSRV Q + ERS+HIFYQI+ E E LL + +Y+++ IT+P++
Sbjct: 268 TYLLEKSRVTFQLKAERSYHIFYQIMSN-KKPELIEMLLITTNPYDYQYVSQGEITVPSI 326
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
+D +E +T +++ I+GF DE ++I ++ AV+ GNL+F Q+++ +QA V K
Sbjct: 327 NDQEELMATDSAIDILGFTPDEKTAIYKLTGAVMHYGNLKFKQKQREEQAEPGGTEVADK 386
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L+GL +L KA PR+KVG E+V K Q +Q +V A+AK+ +E++F W+V RI
Sbjct: 387 AAYLMGLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNSVGALAKSVFEKMFLWMVVRI 446
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 447 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H K
Sbjct: 506 KEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNN 565
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P + ++HF++VHYAG VDY+ WL KN DPLNE VVGL Q S+ +A +
Sbjct: 566 FQKPKPGKGKLEAHFSLVHYAGTVDYNITGWLEKNKDPLNETVVGLYQKSSLKTLALL-- 623
Query: 1870 DAEFAGICAAEMNETAFGMRSRK---GMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIP 2040
FA + AE A G + K F+TVS L +E L KLM+ LR+T PHFVRC+IP
Sbjct: 624 ---FASVGGAEAESGAGGKKGGKKKGSSFQTVSALFRENLNKLMSNLRSTHPHFVRCLIP 680
Query: 2041 NHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NF 2217
N K G + LVL QLRCNGVLEGIRICR+GFP R+ + +F+ RY++L IP+ F
Sbjct: 681 NETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPIRILYADFKQRYKVLNASAIPEGQF 740
Query: 2218 IDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGF 2397
ID K++ K++ ++D+D Y+ G +KVFF+ G+L LEE RD KL LI QA+CRGF
Sbjct: 741 IDSKKASEKLLGSIDVDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQARCRGF 800
Query: 2398 LSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDE 2577
L R + N A++ +++W W +LF K+KPLL+ ++ E+ +E
Sbjct: 801 LMRVEFKKMMERRECIFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAESEKEMANMKEE 860
Query: 2578 LRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQEL 2757
TKE L K E +E E+K+ ++ E+ +Q Q+Q E++ A+ ++ +L +L
Sbjct: 861 FEKTKEELAKSEAKRKELEEKMVSLLQEKNDLQLQVQAEADGLADAEERCDQLIKTKIQL 920
Query: 2758 EYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXX 2937
E + ++ +R +RK + + +K +
Sbjct: 921 EAKIKELTERAEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKV 980
Query: 2938 XXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELE 3117
+ L E++ KAK +LE Q+ +LE
Sbjct: 981 KNLTEEMAALDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLE 1040
Query: 3118 QDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYD 3297
L +E++ + +LE+ KRKL +L+ +++ + ++L+ +L K+D E+ ++ +
Sbjct: 1041 GSLEQEKKLRMDLERAKRKLEGDLKMTQESTMDLENDKQQLDEKLKKKDFEISQIQSKIE 1100
Query: 3298 EESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVD 3477
+E A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L++
Sbjct: 1101 DEQALGMQLQKKIKELQARIEELEEEIEAERTSRAKAEKHRADLSRELEEI-SERLEEAG 1159
Query: 3478 EATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQR 3654
AT Q D+ +++ E +R +E+ E + K + ++ +QI+ ++ +
Sbjct: 1160 GATAAQIDMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSTADVGEQIDNLQRVK 1219
Query: 3655 SQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLI 3834
+LEK++++ E D+A + + ++A+++K + E L EI+ + +E +RT+
Sbjct: 1220 QKLEKEKSELKMEIDDLASNMESVSKAKANLEKMCRSLEDQLSEIK---TKEEEQQRTIN 1276
Query: 3835 D---QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANIN 4005
D Q R + E +R EE++ + + R + K +
Sbjct: 1277 DISAQKARLQTESGEYSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKKCPAH 1336
Query: 4006 RARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNL 4185
+ + + L ++ EE + + L++ + A + R K E Q+ EEL +
Sbjct: 1337 ALQSARHDCDLLREQYEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKK 1396
Query: 4186 RDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFES 4356
+ + LQ E E + + ++K+++Q E+ED +++E A+ +K+QK F+
Sbjct: 1397 KLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACAALDKKQKNFDK 1456
Query: 4357 QMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQD 4536
++E + ++ + +A +E R T + + N + +HLE R ++LQQE+ D
Sbjct: 1457 ILSEWKQKYEETQAELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEISD 1516
Query: 4537 SISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSE 4716
+ GK +HELEK K+ +E E ++++ +EE E +L+ E LR+++ +KS+
Sbjct: 1517 LTEQIAEGGKAIHELEKVKKQIEQEKSELQTALEEAEASLEHEEGKILRVQLELNQVKSD 1576
Query: 4717 SDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEV 4896
DR I+ KD E ++ +R L+ + +++ L+ E R ++ A+ +KK+E + E+E QL
Sbjct: 1577 IDRKIAEKDEEIDQLKRNHLRVVDSMQSTLDAEIRSRNEALRLKKKMEGDLNEIEIQLSH 1636
Query: 4897 ANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREA 5076
ANR E + QI ++A +++ED+ + +R+ ++AE E+LR A
Sbjct: 1637 ANRQAAEAQKNLRNTQGVLKDTQIHLDDALRSQEDLKEQVAMVERRANLLQAEIEELRAA 1696
Query: 5077 NEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELA 5247
E ++RK Q K++LE+ I+Q A
Sbjct: 1697 LEQTERSRKVAEQELLDASERVQLLHTQNTSLINTKKKLESDISQIQSEMEDTIQEARNA 1756
Query: 5248 IDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQ 5427
+K +KA + +L E+ + E K++L+++ +D + ++ E E A + Q
Sbjct: 1757 EEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLDQTVKDLQHRLDEAEQLALKGGKKQ 1816
Query: 5428 MAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKS 5607
+ LEA+V+ LE +++ E + A + R+ E+R+ + T Q E++++ + ++L++K
Sbjct: 1817 IQKLEARVRELEGEVDAEQKRSAEAVKGVRKYERRVKELTYQSEEDRKNVLRLQDLVDKL 1876
Query: 5608 NLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+K ++ +RQ +EAE+ + +K R +Q E ++
Sbjct: 1877 QMKVKSYKRQAEEAEELSNVNLSKFRKIQHELEE 1910
Score = 161 bits (408), Expect = 2e-37
Identities = 187/943 (19%), Positives = 397/943 (41%), Gaps = 57/943 (6%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + + +++L + + ELE+ LL E D + + A+ + EE +
Sbjct: 852 KEMANMKEEFEKTKEELAKSEAKRKELEEKMVSLLQEKNDLQLQVQAEADGLADAEERCD 911
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE N L K+ R ++ EL++D++ E
Sbjct: 912 QLIKTKIQLEAKIKELTERAEDEEEMNAELTAKK-RKLEDECSELKKDIDD-------LE 963
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E L + +++ +E A + A +Q ++ +
Sbjct: 964 LTLAKVEKEKHATENKVKNLTEEMAALDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1023
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIAL-LQASRADID 3750
+ + K K +QV++L +EQ KK R LE+ + + + + M QE + L+ + +D
Sbjct: 1024 TLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGD-LKMTQESTMDLENDKQQLD 1082
Query: 3751 KKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLA 3930
+K K + + +IQ+ + E ++ L QL++ EL R+ E EE A R
Sbjct: 1083 EKLKKKDFEISQIQSKI----EDEQALGMQLQKKIKELQ--ARIEELEEEIEAERTSRAK 1136
Query: 3931 TAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQ 4110
RL+ A A Q++ +++K EAE
Sbjct: 1137 AEKHRADLSRELEEISERLEEAGGATAAQID------MNKKREAE--------------- 1175
Query: 4111 GAGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELE 4281
+ RR EE+ Q LRKK+ + +Q++ + K+++ + K +++ E++
Sbjct: 1176 -FQKMRRDLEEATLQHEATAAALRKKHADSTADVGEQIDNLQRVKQKLEKEKSELKMEID 1234
Query: 4282 DSSMELENVRASHRDSEKRQKKFESQMAEER------------VAVQKALLDRDA--MSQ 4419
D + +E+V + + EK + E Q++E + ++ QKA L ++ S+
Sbjct: 1235 DLASNMESVSKAKANLEKMCRSLEDQLSEIKTKEEEQQRTINDISAQKARLQTESGEYSR 1294
Query: 4420 ELRDRETRVLSL-------LNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHE 4578
++ +++ + L +++ +K HLEE + ++ LQ + + D + E
Sbjct: 1295 QVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKKCPAHALQSARHDCDLLREQYEE 1354
Query: 4579 LEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDR---------AI 4731
++AK L+ L+ + E + + DA R E +A K + R A+
Sbjct: 1355 EQEAKGELQRALS--KANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAV 1412
Query: 4732 SNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLK 4911
++K E+ ++ L ++ DL ++E + +K + + E +Q+ E
Sbjct: 1413 NSKCASLEKTKQRLQNEVEDLMIDVERSNAACAALDKKQKNFDKILSEWKQKYE------ 1466
Query: 4912 EEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLM 5091
E Q E E +++ ++ L + + E L+ N+ L
Sbjct: 1467 ---------------ETQAELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQ 1511
Query: 5092 QARKQXXXXXXXXXXXRAKGGGISSE---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQR 5262
Q A+GG E K+++E + ++ +++ E K
Sbjct: 1512 QEISDLTEQI-------AEGGKAIHELEKVKKQIEQEKSELQTALEEAEASLEHEEGKIL 1564
Query: 5263 KAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAAL- 5439
+ Q++L Q+ +D +++K + + +++ R++ + ++S + R++ AL
Sbjct: 1565 RVQLELNQVKSD------IDRKIAEKDEEIDQLKRNHLRVVDSMQSTLDAEIRSRNEALR 1618
Query: 5440 -----EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEK 5604
E + +E QL+ ++ A + R + L DT +D R+ E KE +
Sbjct: 1619 LKKKMEGDLNEIEIQLSHANRQAAEAQKNLRNTQGVLKDTQIHLDDALRSQEDLKEQVAM 1678
Query: 5605 SNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQL 5733
+ L+ +++E + + + ++E LLDA+E++
Sbjct: 1679 VERRANLLQAEIEELRAALEQTERSRKVAEQE---LLDASERV 1718
Score = 134 bits (337), Expect = 3e-29
Identities = 171/891 (19%), Positives = 364/891 (40%), Gaps = 86/891 (9%)
Frame = +1
Query: 3325 QKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVD-EATMLQDL 3501
+K+M +M+ ++ +E++ R + E E + L + K D+ +V EA L D
Sbjct: 851 EKEMANMKEEFEKTKEELAKSEAKRKELE----EKMVSLLQEKNDLQLQVQAEADGLADA 906
Query: 3502 MSRKDEEVNA-----------TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKK 3648
R D+ + T+RA ++ + M ++ +K K + EL I+ +
Sbjct: 907 EERCDQLIKTKIQLEAKIKELTERAEDEEE--MNAELTAKKRKLEDECSELKKDIDDLEL 964
Query: 3649 QRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRK-IHEAHLMEIQANLAESDEHKR 3825
+++EK+++ + + ++ +E+A L + A + K++K + EAH + AE D+
Sbjct: 965 TLAKVEKEKHATENKVKNLTEEMAALDETIAKLTKEKKALQEAHQQTLDDLQAEEDK-VN 1023
Query: 3826 TLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANIN 4005
TL + ++D L E+E+ +++R A
Sbjct: 1024 TLTKAKTKLEQQVDDLEGSLEQEKKLRMDLER------------------------AKRK 1059
Query: 4006 RARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNL 4185
L+ + + +D + + + L L+K+ Q +++ + E+++ QL++ K+
Sbjct: 1060 LEGDLKMTQESTMDLENDKQQLDEKLKKKDFEISQI--QSKIEDEQALGMQLQKKIKELQ 1117
Query: 4186 RDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMA 4365
+E L++++E ++ + + + + +ELE+ S LE + KK E++
Sbjct: 1118 ARIEELEEEIEAERTSRAKAEKHRADLSRELEEISERLEEAGGATAAQIDMNKKREAEFQ 1177
Query: 4366 EERVAVQKALLDRDAMSQELRDRETRVLSLLNE-VDIMKEHLEESDRVRRSLQQELQDSI 4542
+ R +++A L +A + LR + + + E +D ++ ++ ++ + L+ E+ D
Sbjct: 1178 KMRRDLEEATLQHEATAAALRKKHADSTADVGEQIDNLQRVKQKLEKEKSELKMEIDDLA 1237
Query: 4543 SNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQ--IAEDARLRLEVTNQALKSE 4716
SN + K LEK RSLE +L++++ + EE + + A+ ARL+ E E
Sbjct: 1238 SNMESVSKAKANLEKMCRSLEDQLSEIKTKEEEQQRTINDISAQKARLQTE------SGE 1291
Query: 4717 SDRAISNKDVEAEEKRRG---LLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQ 4887
R + KD + RG +QI +L+ LE E + K + + L +Q
Sbjct: 1292 YSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKKCPAHALQSARHDCDLLREQ 1351
Query: 4888 LEVANRLKEEYXXXXXXXXXXXXEYQIE--------CEEARQAKEDIAALLREADRKFRA 5043
E K E +++ + EE +AK+ +A L++A+ A
Sbjct: 1352 YEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEA 1411
Query: 5044 V-------EAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQ 5202
V E +++L+ E LM ++ + I SE K++ E A+
Sbjct: 1412 VNSKCASLEKTKQRLQNEVEDLMIDVERSNAACAALDKKQKNFDKILSEWKQKYEETQAE 1471
Query: 5203 XXXXXXXXQS-----------------NCELAIDKQRKAQVQLEQITTDLSMERTLNQKT 5331
+S + E + + Q ++ +T ++ +
Sbjct: 1472 LEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKAIHEL 1531
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRA----RAQMAALEAK----------------- 5448
E K+ +E+ + + + E E+ + R Q+ + K
Sbjct: 1532 EKVKKQIEQEKSELQTALEEAEASLEHEEGKILRVQLELNQVKSDIDRKIAEKDEEIDQL 1591
Query: 5449 -------VQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKS 5607
V ++ L+ E + + A R +++E LN+ Q R +A++ L +
Sbjct: 1592 KRNHLRVVDSMQSTLDAEIRSRNEALRLKKKMEGDLNEIEIQLSHANRQAAEAQKNLRNT 1651
Query: 5608 NLKNRNLRRQLDEA-------EDEMSRERTKHRNVQREADDLLDANEQLTR 5739
++ + LD+A +++++ + +Q E ++L A EQ R
Sbjct: 1652 QGVLKDTQIHLDDALRSQEDLKEQVAMVERRANLLQAEIEELRAALEQTER 1702
Score = 115 bits (287), Expect = 2e-23
Identities = 173/910 (19%), Positives = 359/910 (39%), Gaps = 132/910 (14%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ T+E + +E+D ++ ++KL + E + IQ +++ E +L LQ
Sbjct: 1058 RKLEGDLKMTQESTMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQ 1117
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + +R S R ++E + + +
Sbjct: 1118 ARIEELEEEIE--AERTSRAKAEKHRADLSR--ELEEISERLEEAGGATAAQIDMNKKRE 1173
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K L+
Sbjct: 1174 AEFQKMRRDLEEATLQHEATAAALRKKHADSTADVG---EQIDNLQRVKQKLEKEKSELK 1230
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K+ LE+ R L +L + K E+ + +++ Q + E
Sbjct: 1231 MEIDDLASNMESVSKAKANLEKMCRSLEDQLSEIKTKEEEQQRTINDISAQKARLQTESG 1290
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ +E+ A ++ + + + I+EL+ +E E A+ + + ++
Sbjct: 1291 EYSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKKCPAHALQSARHDCDLLRE 1350
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
++ + LQ +S+ + EV TK + IQ T E +EE K K ++++++ +
Sbjct: 1351 QYEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQDAEEH 1408
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME-------I 3789
+E + + LEK + + E D+ ++ A+ A +DKK+K + L E
Sbjct: 1409 VEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACAALDKKQKNFDKILSEWKQKYEET 1468
Query: 3790 QANLAESDEHKRTL--------------IDQLERSRDE---------------------L 3864
QA L S + R+L +D LE + E +
Sbjct: 1469 QAELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKAI 1528
Query: 3865 DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKI----ANINRARQLEDE- 4029
L +V+++ E + +Q L A +L++ ++I+R +DE
Sbjct: 1529 HELEKVKKQIEQEKSELQTALEEAEASLEHEEGKILR-VQLELNQVKSDIDRKIAEKDEE 1587
Query: 4030 -------------------------KNALLDEKEEAEGLRAHLEKEIHAARQGAGEARR- 4131
+N L K++ EG +E ++ A + A EA++
Sbjct: 1588 IDQLKRNHLRVVDSMQSTLDAEIRSRNEALRLKKKMEGDLNEIEIQLSHANRQAAEAQKN 1647
Query: 4132 -------------------KAEESVNQQLEEL-RKKNLRDVEHLQKQLEESEVAKERILQ 4251
+++E + +Q+ + R+ NL LQ ++EE A E+ +
Sbjct: 1648 LRNTQGVLKDTQIHLDDALRSQEDLKEQVAMVERRANL-----LQAEIEELRAALEQTER 1702
Query: 4252 SKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRD 4431
S+K +QEL D+S ++ + + +KK ES +++ + ++ + QE R+
Sbjct: 1703 SRKVAEQELLDASERVQLLHTQNTSLINTKKKLESDISQIQSEMEDTI-------QEARN 1755
Query: 4432 RETRVLSLLNEVDIMKEHLEES-------DRVRRSLQQELQDSISNKDDFG--------K 4566
E + + + +M E L++ +R++++L Q ++D D+ K
Sbjct: 1756 AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLDQTVKDLQHRLDEAEQLALKGGKK 1815
Query: 4567 NVHELEKAKRSLEAELN---------------------DMRVQMEELEDNLQIAEDARLR 4683
+ +LE R LE E++ ++ Q EE N+ +D +
Sbjct: 1816 QIQKLEARVRELEGEVDAEQKRSAEAVKGVRKYERRVKELTYQSEEDRKNVLRLQDLVDK 1875
Query: 4684 LEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIEN 4863
L++ ++ K +++ EAEE L + R +++ELE + A S K+
Sbjct: 1876 LQMKVKSYKRQAE--------EAEELSNVNLSKFRKIQHELEEAEERADIAESQVNKLRA 1927
Query: 4864 QIGELEQQLE 4893
+ E+ ++ E
Sbjct: 1928 KSREIGKKAE 1937
Score = 73.9 bits (180), Expect = 4e-11
Identities = 98/457 (21%), Positives = 196/457 (42%), Gaps = 40/457 (8%)
Frame = +1
Query: 4492 ESDRVRRSLQQELQDSISNKDDFGKNV---HELEKAKRSLEAELNDMRVQMEELEDNLQI 4662
ES++ ++++E + + K++ K+ ELE+ SL E ND+++Q++ D L
Sbjct: 849 ESEKEMANMKEEFEKT---KEELAKSEAKRKELEEKMVSLLQEKNDLQLQVQAEADGLAD 905
Query: 4663 AE---DARLRLEVTNQA-LKSESDRAISNKDVEAE--EKRRGLLKQIRDLENELENEKRG 4824
AE D ++ ++ +A +K ++RA +++ AE K+R L + +L+ ++++ +
Sbjct: 906 AEERCDQLIKTKIQLEAKIKELTERAEDEEEMNAELTAKKRKLEDECSELKKDIDDLELT 965
Query: 4825 KSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDI 5004
+ + EN++ L +++ +E E + + QA+ED
Sbjct: 966 LAKVEKEKHATENKVKNLTEEMAAL----DETIAKLTKEKKALQEAHQQTLDDLQAEEDK 1021
Query: 5005 AALLREADRKFRA----VEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEE 5172
L +A K +E EQ ++ L +A+++ +
Sbjct: 1022 VNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKMTQESTMD----LEND 1077
Query: 5173 KRRLEAKIAQXXXXXXXXQSNCE----LAIDKQRKA---QVQLEQITTDLSMERTLNQKT 5331
K++L+ K+ + QS E L + Q+K Q ++E++ ++ ERT K
Sbjct: 1078 KQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERTSRAKA 1137
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRARAQM-AALEAKVQYLEDQLNVEGQEKTAANR 5508
E + L R + ++ E +G + A+ M EA+ Q + L +E T +
Sbjct: 1138 EKHRADLSRELEEISERLEE--AGGATAAQIDMNKKREAEFQKMRRDL----EEATLQHE 1191
Query: 5509 A-ARRLEKRLNDTTQQFEDEKRANEQAKELLEK-------------SNLKN-----RNLR 5631
A A L K+ D+T ++ ++ K+ LEK SN+++ NL
Sbjct: 1192 ATAAALRKKHADSTADVGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMESVSKAKANLE 1251
Query: 5632 RQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
+ ED++S +TK QR +D+ +L E
Sbjct: 1252 KMCRSLEDQLSEIKTKEEEQQRTINDISAQKARLQTE 1288
Score = 54.7 bits (130), Expect = 3e-05
Identities = 71/329 (21%), Positives = 136/329 (40%), Gaps = 31/329 (9%)
Frame = +1
Query: 4852 KIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADR 5031
KI+ + E + E+AN +KEE+ + ++ +E + +LL+E +
Sbjct: 840 KIKPLLKSAESEKEMAN-MKEEFEKTKEELAKSEAK-------RKELEEKMVSLLQEKND 891
Query: 5032 KFRAVEAEREQLREANEG---LMQARKQXXXXXXXXXXXRAKGGGISSE---EKRRLEAK 5193
V+AE + L +A E L++ + Q +++E +KR+LE +
Sbjct: 892 LQLQVQAEADGLADAEERCDQLIKTKIQLEAKIKELTERAEDEEEMNAELTAKKRKLEDE 951
Query: 5194 IAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEA----EKQSLERS 5361
++ + EL + K K + E +L+ E +T A EK++L+ +
Sbjct: 952 CSELKKDI----DDLELTLAKVEKEKHATENKVKNLTEEMAALDETIAKLTKEKKALQEA 1007
Query: 5362 NRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLND 5541
++ + E + +A+ LE +V LE L E + + RA R+LE L
Sbjct: 1008 HQQTLDDLQAEEDKVNTLTKAK-TKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKM 1066
Query: 5542 TTQQFEDEKRANEQAKELLEKSNL---------------------KNRNLRRQLDEAEDE 5658
T + D + +Q E L+K + K + L+ +++E E+E
Sbjct: 1067 TQESTMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQARIEELEEE 1126
Query: 5659 MSRERTKHRNVQREADDLLDANEQLTREL 5745
+ ERT ++ DL E+++ L
Sbjct: 1127 IEAERTSRAKAEKHRADLSRELEEISERL 1155
Score = 38.1 bits (87), Expect = 2.6
Identities = 48/284 (16%), Positives = 102/284 (35%), Gaps = 4/284 (1%)
Frame = +1
Query: 2548 DDEIRAKDD---ELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELD 2718
DD +R+++D ++ + R ++ + E L+Q R V +++L SE L
Sbjct: 1663 DDALRSQEDLKEQVAMVERRANLLQAEIEELRAALEQTERSRKVAEQELLDASERVQLLH 1722
Query: 2719 DIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXX 2898
L ++LE ++ ++ + +K +
Sbjct: 1723 TQNTSLINTKKKLESDISQIQSEMEDTIQEARNAEEKAKKAITDAAMMAEELKKEQDTSA 1782
Query: 2899 XXXXDKTNVDQXXXXXXXXXXXXQD-AYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV 3075
K N+DQ + A L ++ ++R+ V
Sbjct: 1783 HLERMKKNLDQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVDAEQKRSAEAV 1842
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLM 3255
K + E ++ EL +R+ L+ KL +++ K E EEL+N +
Sbjct: 1843 KGVRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQMKVKSYKRQAEE----AEELSNVNL 1898
Query: 3256 KRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETE 3387
+ ++QH+L +E + + Q+ ++ E+ + E+E
Sbjct: 1899 SKFRKIQHEL---EEAEERADIAESQVNKLRAKSREIGKKAESE 1939
>gi|15384839|emb|CAC59753.1| myosin heavy chain [Paracirrhites
forsteri]
Length = 1936
Score = 1105 bits (2857), Expect = 0.0
Identities = 652/1903 (34%), Positives = 1060/1903 (55%), Gaps = 17/1903 (0%)
Frame = +1
Query: 52 ATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKF 231
A A + + +V D +E +L G + + + V+ D+ + +T+ DD+ NPPK+
Sbjct: 27 AQTAPFDAKTAFFVADVDEMYLKGKLAKREGGKATVD-TDSGKSLTVKEDDIHPRNPPKY 85
Query: 232 DKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKG 411
DKIEDM+ +T+LNE VL+NLK+RY S +IYTYSGLFCVV+NPYK LP+Y ++ ++G
Sbjct: 86 DKIEDMAMMTHLNEPCVLYNLKERYASWMIYTYSGLFCVVVNPYKWLPVYDAQVVAAYRG 145
Query: 412 KKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRN 591
KKR E PPHIF+I+D AY+ ML +RE+QS+L TGESGAGKT NTK+VIQY A +A
Sbjct: 146 KKRIEAPPHIFSISDNAYQFMLTDRENQSVLITGESGAGKTVNTKRVIQYFATIAALGAK 205
Query: 592 KSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINF 771
K+ +P G LE Q++ ANP+LEA+GN+KTV+NDNSSRFGKFIRI+F
Sbjct: 206 KA-----------EPTPGKMQGSLEDQIVAANPLLEAYGNAKTVRNDNSSRFGKFIRIHF 254
Query: 772 DMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRF- 948
+G +S A+IE YLLEKSRV Q ERS+HIFYQ++ G E E LL + Y +
Sbjct: 255 GTTGKLSSADIETYLLEKSRVTFQLSAERSYHIFYQLMTG-HKPELLEGLLITTNPYDYP 313
Query: 949 LVNRG-ITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSD 1125
++++G IT+ +++DV+EF +T ++ I+GF +E I ++ AV+ GN++F Q+++ +
Sbjct: 314 MISQGEITVKSINDVEEFIATDTAIDILGFNAEEKIGIYKLTGAVMHHGNMKFKQKQREE 373
Query: 1126 QAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKAS 1305
QA V K+ +LLGL ++ KA PR+KVG E V K Q Q AV A+ K+
Sbjct: 374 QAEPDGTEVADKIAYLLGLNSADMLKALCYPRVKVGNEMVTKGQTVPQVNNAVSALCKSV 433
Query: 1306 YERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFN 1485
YE++F W+V RIN+ LD T + + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN
Sbjct: 434 YEKMFLWMVIRINEMLD-TKQPRSYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFN 492
Query: 1486 NTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVE 1665
+ MF+LEQEEY++EGI+W+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA+D +F
Sbjct: 493 HHMFVLEQEEYKKEGIDWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKASDTTFKN 552
Query: 1666 KLQKTH-NKHPKFIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQ 1833
KL H K F P ++++HFA+VHYAG VDY+ WL KN DPLN++VV L Q
Sbjct: 553 KLHDQHLGKTKAFEKPKPGKGKAEAHFALVHYAGTVDYNISGWLDKNKDPLNDSVVQLYQ 612
Query: 1834 NSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTS 2013
S++ +A ++ A AG A E G + + G F+TVS L +E L KLMT LR+T
Sbjct: 613 KSSNKLLAMLY--AAHAG--AEEAAGGKKGGKKKGGSFQTVSALFRENLGKLMTNLRSTH 668
Query: 2014 PHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILT 2193
PHFVRC+IPN K G + + LV+ QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L
Sbjct: 669 PHFVRCLIPNETKTPGLMENFLVIHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLN 728
Query: 2194 PDVIPK-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIM 2370
VIP+ FID K++ K++ ++D+D Y+ G +KVFF+ G+L LEE RD KL L+
Sbjct: 729 ASVIPEGQFIDNKKASEKLLGSIDVDHTQYKFGHTKVFFKAGLLGTLEEMRDDKLATLVT 788
Query: 2371 NFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTD 2550
QA CRG++ R+ Y N +++ ++NW W +L+ K+KPLL+ T+
Sbjct: 789 MTQALCRGYVMRKEYVKMTERRESIYSIQYNIRSFMNVKNWPWLKLYFKIKPLLKSAETE 848
Query: 2551 DEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRG 2730
E++ + L +E E+K+ ++ E+ +Q Q+ E EN + ++
Sbjct: 849 KELQQMKENYDKMTSDLAAALAKKKELEEKMVSLLQEKNDLQLQVAAEVENLGDAEERCE 908
Query: 2731 RLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXX 2910
L +LE + + +RL +RK +
Sbjct: 909 GLIKSKIQLEAKLKETGERLEDEEEINAELTAKKRKLEDECSQLKKDIDDLELTLAEVEK 968
Query: 2911 DKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGR 3090
+K + + L E++ KAK +
Sbjct: 969 EKHATENKVKNLTEEMASQDETVAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTK 1028
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
LE Q+ +LE L +E++ + +LE+ KRKL +L+ S++ + + ++ + ++ K+D E
Sbjct: 1029 LEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLSQESIMDLENDKQQSDEKIKKKDFE 1088
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
L++ ++E + +QK+++++Q I+EL E++E ER AR K E R ++ +LE++
Sbjct: 1089 TSQLLSKIEDEQSLGAQLQKKIKELQARIEELEEEIEAERAARAKVEKQRADLSRELEEI 1148
Query: 3451 KGDVLDKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+ L++ AT Q M++K E E +R +E+ E + K + V EL
Sbjct: 1149 -SERLEEAGGATAAQIEMNKKREAEFQKLRRDLEESTLQHEATASALRKKQADSVAELGQ 1207
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAE 3807
QI+ ++ + +LEK++++ E D++ + + ++ +++K + E L E++ A+
Sbjct: 1208 QIDNLQRVKQKLEKEKSEYKMEIDDLSSNMEAVAKAKGNLEKMCRTVEDQLSELK---AK 1264
Query: 3808 SDEHKRTLID---QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXX 3978
+DE+ R L D Q R + E +R EE+E + + R
Sbjct: 1265 NDENVRQLNDINAQKARLQTENGEYSRQLEEKEALVSQLTRGKQAFTQQIEELKRHVEEE 1324
Query: 3979 TRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQ 4158
+ K A + + + + L ++ EE + +A L++ + A + R K E Q+
Sbjct: 1325 VKAKNALAHGVQSSRHDCDLLREQFEEEQEAKAELQRGMSKANSEVAQWRSKYETDAIQR 1384
Query: 4159 LEELRKKNLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDS 4329
EEL + + + LQ+ E E + + ++K+++Q E+ED +++E A +
Sbjct: 1385 TEELEEAKKKLAQRLQEAEESIEAVNSKCASLEKTKQRLQGEVEDLMIDVERANALAANL 1444
Query: 4330 EKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVR 4509
+K+Q+ F+ +AE + ++ + + +E R T + + N + +HLE R
Sbjct: 1445 DKKQRNFDKVLAEWKQKYEEGQAELEGAQKEARSLSTELFKMKNSYEEALDHLETMKREN 1504
Query: 4510 RSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLE 4689
++LQQE+ D + GK++HELEKAK+++E E +++ +EE E L+ E LR++
Sbjct: 1505 KNLQQEISDLTEQIGETGKSIHELEKAKKTVETEKTEIQSALEEAEGTLEHEEAKILRVQ 1564
Query: 4690 VTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQI 4869
+ +K E DR ++ KD E E+ +R + I +++ L++E R ++ A+ +KK+E +
Sbjct: 1565 LELNQIKGEVDRKMAEKDEEMEQIKRNSQRVIDSMQSTLDSEVRSRNDALRVKKKMEGDL 1624
Query: 4870 GELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVE 5049
E+E QL ANR E + Q+ ++A + +ED+ + +R+ +
Sbjct: 1625 NEMEIQLSHANRQASEAQKQLRNVQGQLKDAQLHLDDAVRGQEDMKEQVAMVERRNGLMM 1684
Query: 5050 AEREQLREANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXX 5220
AE ++LR A E + RK Q K++LEA + Q
Sbjct: 1685 AEIDELRVALEQTERGRKVAEQELVDASERVGLLHSQNTSLMNTKKKLEADLVQVQGEVD 1744
Query: 5221 XXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES 5400
A DK +KA + +L E+ + E K++LE + +D + ++ E E+
Sbjct: 1745 DTVQEARNAEDKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEVTVKDLQHRLDEAEN 1804
Query: 5401 GAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANE 5580
A + Q+ LE++V+ LE ++ E + A + R+ E+R+ + T Q E++K+
Sbjct: 1805 LAMKGGKKQLQKLESRVRELESEVEAEQRRGADAVKGVRKYERRVKELTYQTEEDKKNVN 1864
Query: 5581 QAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+ ++L++K LK ++ +RQ +EAE++ + ++ R VQ E ++
Sbjct: 1865 RLQDLVDKLQLKVKSYKRQSEEAEEQANTHMSRLRKVQHELEE 1907
Score = 128 bits (322), Expect = 1e-27
Identities = 146/830 (17%), Positives = 332/830 (39%), Gaps = 13/830 (1%)
Frame = +1
Query: 3262 DEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQL 3441
++ELQ YD+ ++++ + + EL E M + +N ++ V L
Sbjct: 848 EKELQQMKENYDKMTSDLAAALAKKK-------ELEEKMVSLLQEKNDLQLQVAAEVENL 900
Query: 3442 ----EKVKGDVLDKVDEATMLQDLMSR--KDEEVNATKRAIEQIQHTMEGKIEEQKAKFS 3603
E+ +G + K+ L++ R +EE+NA A ++ K+E++ ++
Sbjct: 901 GDAEERCEGLIKSKIQLEAKLKETGERLEDEEEINAELTAKKR-------KLEDECSQLK 953
Query: 3604 RQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLM 3783
+ +++L + + +K++ E + +E A + +A L +K+ + EAH
Sbjct: 954 KDIDDLELTLAEVEKEKHATENKVKNLTEEMASQDETVAKLTK------EKKALQEAHQQ 1007
Query: 3784 EIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXX 3963
+ AE D+ TL + ++D L E+E+ +++R
Sbjct: 1008 TLDDLQAEEDK-VNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLSQE 1066
Query: 3964 XXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEE 4143
K + + ++ + E + LL + E+ + L A L+K+I
Sbjct: 1067 SIMDLENDKQQSDEKIKKKDFETSQLLSKIEDEQSLGAQLQKKI---------------- 1110
Query: 4144 SVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHR 4323
+EL+ + +E L++++E A+ ++ + + + +ELE+ S LE +
Sbjct: 1111 ------KELQAR----IEELEEEIEAERAARAKVEKQRADLSRELEEISERLEEAGGATA 1160
Query: 4324 DSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDR 4503
+ KK E++ + R ++++ L +A + LR ++
Sbjct: 1161 AQIEMNKKREAEFQKLRRDLEESTLQHEATASALRKKQA--------------------- 1199
Query: 4504 VRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLR 4683
DS++ + G+ + L++ K+ LE E ++ ++++++L N++ A+
Sbjct: 1200 ----------DSVA---ELGQQIDNLQRVKQKLEKEKSEYKMEIDDLSSNMEAVAKAKGN 1246
Query: 4684 LEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIEN 4863
LE + R + ++ E + K ++Q+ D+ + + +++
Sbjct: 1247 LE--------KMCRTVEDQLSELKAKNDENVRQLNDIN--------------AQKARLQT 1284
Query: 4864 QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIA----ALLREADR 5031
+ GE +QLE L + E + EE +AK +A + + D
Sbjct: 1285 ENGEYSRQLEEKEALVSQLTRGKQAFTQQIEELKRHVEEEVKAKNALAHGVQSSRHDCDL 1344
Query: 5032 KFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXX 5211
E E+E E G+ +A + + E K++L ++ +
Sbjct: 1345 LREQFEEEQEAKAELQRGMSKANSEVAQWRSKYETDAIQRTEELEEAKKKLAQRLQEAEE 1404
Query: 5212 XXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITE 5391
S C +++ Q ++E + D+ L + ++++ ++ ++K K E
Sbjct: 1405 SIEAVNSKCASLEKTKQRLQGEVEDLMIDVERANALAANLDKKQRNFDKVLAEWKQKYEE 1464
Query: 5392 LES---GAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFED 5562
++ GAQ AR+ L E+ L+ R + L++ ++D T+Q +
Sbjct: 1465 GQAELEGAQKEARSLSTELFKMKNSYEEALD----HLETMKRENKNLQQEISDLTEQIGE 1520
Query: 5563 EKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
++ + ++ + + ++ L+EAE + E K VQ E + +
Sbjct: 1521 TGKSIHELEKAKKTVETEKTEIQSALEEAEGTLEHEEAKILRVQLELNQI 1570
Score = 127 bits (318), Expect = 4e-27
Identities = 177/891 (19%), Positives = 361/891 (39%), Gaps = 125/891 (14%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ ++E ++ +E+D +++++K+ + E + + +++ E A+L LQ
Sbjct: 1055 RKLEGDLKLSQESIMDLENDKQQSDEKIKKKDFETSQLLSKIEDEQSLGAQLQKKIKELQ 1114
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + R +++E + + +
Sbjct: 1115 ARIEELEEEIEAER----AARAKVEKQRADLSRELEEISERLEEAGGATAAQIEMNKKRE 1170
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G Q +D+ +R K + K K +
Sbjct: 1171 AEFQKLRRDLEESTLQHEATASALRKKQADSVAELG---QQIDNLQRVKQKLEKEKSEYK 1227
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K LE+ R + +L + K E + ++ ++N Q + E
Sbjct: 1228 MEIDDLSSNMEAVAKAKGNLEKMCRTVEDQLSELKAKNDENVRQLNDINAQKARLQTENG 1287
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ +E+ A V+ + + + I+EL+ +E E A+N + + ++
Sbjct: 1288 EYSRQLEEKEALVSQLTRGKQAFTQQIEELKRHVEEEVKAKNALAHGVQSSRHDCDLLRE 1347
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
++ + LQ MS+ + EV +K + IQ T E +EE K K +++++E +
Sbjct: 1348 QFEEEQEAKAELQRGMSKANSEVAQWRSKYETDAIQRTEE--LEEAKKKLAQRLQEAEES 1405
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEI------- 3789
IE + + LEK + + E D+ ++ A A++DKK++ + L E
Sbjct: 1406 IEAVNSKCASLEKTKQRLQGEVEDLMIDVERANALAANLDKKQRNFDKVLAEWKQKYEEG 1465
Query: 3790 QANLAESDEHKRTLIDQLERSRDE----LDHLNRVREEEEHAFANMQRRLATAXXXXXXX 3957
QA L + + R+L +L + ++ LDHL ++ E + N+Q+ ++
Sbjct: 1466 QAELEGAQKEARSLSTELFKMKNSYEEALDHLETMKRENK----NLQQEISDLTEQIGE- 1520
Query: 3958 XXXXXXXTRLKIANINRARQ-LEDEKNALLDEKEEAEGLRAHLEKEIHAAR----QGAGE 4122
T I + +A++ +E EK + EEAEG H E +I + Q GE
Sbjct: 1521 -------TGKSIHELEKAKKTVETEKTEIQSALEEAEGTLEHEEAKILRVQLELNQIKGE 1573
Query: 4123 ARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
RK E ++++E++++ + R ++ +Q L+ ++ L+ KKK++ +L + ++L
Sbjct: 1574 VDRKMAEK-DEEMEQIKRNSQRVIDSMQSTLDSEVRSRNDALRVKKKMEGDLNEMEIQLS 1632
Query: 4303 --------------NVRASHRDS---------------------EKRQKKFESQMAEERV 4377
NV+ +D+ E+R +++ E RV
Sbjct: 1633 HANRQASEAQKQLRNVQGQLKDAQLHLDDAVRGQEDMKEQVAMVERRNGLMMAEIDELRV 1692
Query: 4378 AVQKALLDRDAMSQELRDRETRV-------LSLLN-----EVDIMKEHLEESDRVR--RS 4515
A+++ R QEL D RV SL+N E D+++ E D V+ R+
Sbjct: 1693 ALEQTERGRKVAEQELVDASERVGLLHSQNTSLMNTKKKLEADLVQVQGEVDDTVQEARN 1752
Query: 4516 LQQELQDSISN--------KDDFGKNVHELEKAKRSLEAELNDMRVQMEELED------- 4650
+ + + +I++ K + + H LE+ K++LE + D++ +++E E+
Sbjct: 1753 AEDKAKKAITDAAMMAEELKKEQDTSAH-LERMKKNLEVTVKDLQHRLDEAENLAMKGGK 1811
Query: 4651 -NLQIAEDARLRLE-----------------------VTNQALKSESDRAISNK------ 4740
LQ E LE V ++E D+ N+
Sbjct: 1812 KQLQKLESRVRELESEVEAEQRRGADAVKGVRKYERRVKELTYQTEEDKKNVNRLQDLVD 1871
Query: 4741 ------------DVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKI 4857
EAEE+ + ++R +++ELE + A S K+
Sbjct: 1872 KLQLKVKSYKRQSEEAEEQANTHMSRLRKVQHELEEAQERADIAESQVNKL 1922
Score = 94.0 bits (232), Expect = 4e-17
Identities = 131/679 (19%), Positives = 266/679 (38%), Gaps = 57/679 (8%)
Frame = +1
Query: 2470 AYLKLRNWQWWRLFTKVKPLL-QVTRTDDEIRAKDDELRATKERLLK----MEHDFRENE 2634
A L+ N ++ R + + L+ Q+TR + +EL+ E +K + H + +
Sbjct: 1280 ARLQTENGEYSRQLEEKEALVSQLTRGKQAFTQQIEELKRHVEEEVKAKNALAHGVQSSR 1339
Query: 2635 KKLDQVIVERAVIQEQLQQESENSAELD-----------DIRGRLQT----RNQELEYIV 2769
D +++EQ ++E E AEL R + +T R +ELE
Sbjct: 1340 HDCD-------LLREQFEEEQEAKAELQRGMSKANSEVAQWRSKYETDAIQRTEELEEAK 1392
Query: 2770 NDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXX 2949
+ RL +T + N+D+
Sbjct: 1393 KKLAQRLQEAEESIEAVNSKCASLEKTKQRLQGEVEDLMIDVERANALAANLDKKQRNFD 1452
Query: 2950 XXXXXXQDAYDXXXXXXXXXXXXXXGLTTQL----------LDHEERAKHGVKAKGR--- 3090
+ Y+ L+T+L LDH E K K +
Sbjct: 1453 KVLAEWKQKYEEGQAELEGAQKEARSLSTELFKMKNSYEEALDHLETMKRENKNLQQEIS 1512
Query: 3091 -LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDE 3267
L Q+ E + ++ + K +E K ++ + LE+++ L + K+ + +L +
Sbjct: 1513 DLTEQIGETGKSIHELEKAKKTVETEKTEIQSALEEAEGTLEHEEAKILRVQLELNQIKG 1572
Query: 3268 ELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEK 3447
E+ ++ DEE M++ R+ Q ID ++ +++E +RN A ++++ L +
Sbjct: 1573 EVDRKMAEKDEE------MEQIKRNSQRVIDSMQSTLDSEVRSRNDALRVKKKMEGDLNE 1626
Query: 3448 VKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
++ + +A+ Q + ++ + ++ E ++EQ A R+ +
Sbjct: 1627 MEIQLSHANRQASEAQKQLRNVQGQLKDAQLHLDDAVRGQED-MKEQVAMVERRNGLMMA 1685
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAE 3807
+I++ + Q E+ + A+QE D ++ + LL + + +K EA L+++Q + +
Sbjct: 1686 EIDELRVALEQTERGRKVAEQELVDASERVGLLHSQNTSLMNTKKKLEADLVQVQGEVDD 1745
Query: 3808 S--------DEHKRTLID------QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
+ D+ K+ + D +L++ +D HL R+++ E ++Q RL A
Sbjct: 1746 TVQEARNAEDKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEVTVKDLQHRLDEAENL 1805
Query: 3946 XXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEA 4125
+R R+LE E A E+ G A K + + E
Sbjct: 1806 AMKGGKKQLQKLE------SRVRELESEVEA-----EQRRG--ADAVKGVRKYERRVKEL 1852
Query: 4126 RRKAEESVNQ--QLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELED----- 4284
+ EE +L++L K V+ ++Q EE+E + +K+Q ELE+
Sbjct: 1853 TYQTEEDKKNVNRLQDLVDKLQLKVKSYKRQSEEAEEQANTHMSRLRKVQHELEEAQERA 1912
Query: 4285 --SSMELENVRASHRDSEK 4335
+ ++ +RA R++ K
Sbjct: 1913 DIAESQVNKLRAKSRETGK 1931
Score = 64.3 bits (155), Expect = 3e-08
Identities = 97/514 (18%), Positives = 213/514 (40%), Gaps = 21/514 (4%)
Frame = +1
Query: 4261 KIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRET 4440
KI+ L+ + E E ++ + +K + +A+++ +K + ++ QE D +
Sbjct: 837 KIKPLLKSAETEKE-LQQMKENYDKMTSDLAAALAKKKELEEKMV----SLLQEKNDLQL 891
Query: 4441 RVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELND 4620
+V + + + +E E + + L+ +L+++ +D + EL KR LE E +
Sbjct: 892 QVAAEVENLGDAEERCEGLIKSKIQLEAKLKETGERLEDEEEINAELTAKKRKLEDECSQ 951
Query: 4621 MRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAE--EKRRGLLKQIRDL 4794
++ +++LE L E + T +K+ ++ S + A+ ++++ L + +
Sbjct: 952 LKKDIDDLELTLAEVEKEK---HATENKVKNLTEEMASQDETVAKLTKEKKALQEAHQQT 1008
Query: 4795 ENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIEC 4974
++L+ E+ + + K+E Q+ +LE LE +L+ + + + +
Sbjct: 1009 LDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKR-------KLEGDL 1061
Query: 4975 EEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGG 5154
+ ++++ D+ +++D K + + E QL
Sbjct: 1062 KLSQESIMDLENDKQQSDEKIKKKDFETSQLLS--------------------------- 1094
Query: 5155 GISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSME-----RTL 5319
E+++ L A++ + E I+ +R A+ ++E+ DLS E L
Sbjct: 1095 --KIEDEQSLGAQLQKKIKELQARIEELEEEIEAERAARAKVEKQRADLSRELEEISERL 1152
Query: 5320 NQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTA 5499
+ A +E N+ +A+ +L + A A + D + GQ+
Sbjct: 1153 EEAGGATAAQIEM-NKKREAEFQKLRRDLEESTLQHEATASALRKKQADSVAELGQQIDN 1211
Query: 5500 ANRAARRLEKRLNDTTQQFED---EKRANEQAKELLEK---------SNLKNRNLR--RQ 5637
R ++LEK ++ + +D A +AK LEK S LK +N RQ
Sbjct: 1212 LQRVKQKLEKEKSEYKMEIDDLSSNMEAVAKAKGNLEKMCRTVEDQLSELKAKNDENVRQ 1271
Query: 5638 LDEAEDEMSRERTKHRNVQREADDLLDANEQLTR 5739
L++ + +R +T++ R+ ++ QLTR
Sbjct: 1272 LNDINAQKARLQTENGEYSRQLEEKEALVSQLTR 1305
>gi|13431711|sp|Q90339|MYSS_CYPCA Myosin heavy chain, fast skeletal
muscle
gi|2351223|dbj|BAA22069.1| myosin heavy chain [Cyprinus carpio]
Length = 1935
Score = 1104 bits (2856), Expect = 0.0
Identities = 654/1900 (34%), Positives = 1070/1900 (55%), Gaps = 26/1900 (1%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V D +E +L G++ + + V+ + + VT+ D++ NPPKFDKIEDM+ +T+L
Sbjct: 38 FVVDPDEMYLKGTLVSKEGGKATVK-THSGKTVTVKEDEIFPMNPPKFDKIEDMAMMTHL 96
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
NE +VL NLK+RY + +IYTYSGLFCV +NPYK LP+Y ++ ++GKKR E PPHIF+
Sbjct: 97 NEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYDAVVVGGYRGKKRIEAPPHIFS 156
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QS+L TGESGAGKT NTK+VIQY A V + K
Sbjct: 157 ISDNAYQFMLTDRENQSVLITGESGAGKTVNTKRVIQYFATVGAMSGPKK---------- 206
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
+P G LE Q++ ANP+LEA+GN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 207 PEPVPGKMQGSLEDQIVAANPLLEAYGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIE 266
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRF-LVNRG-ITLPNV 981
YLLEKSRV Q ERS+HIFYQ++ G E E LL + Y + ++++G IT+ ++
Sbjct: 267 TYLLEKSRVTFQLSAERSYHIFYQLMTG-HKPELLEALLITTNPYDYPMISQGEITVKSI 325
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
+DV+EF +T ++ I+GF DE SI ++ AV+ GN++F Q+++ +QA V K
Sbjct: 326 NDVEEFIATDTAIDILGFTADEKISIYKLTGAVMHHGNMKFKQKQREEQAEPDGTEVADK 385
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+ +L+GL ++ KA PR+KVG E V K Q Q AV A++K+ YE++F W+V RI
Sbjct: 386 IAYLMGLNSADMLKALCFPRVKVGNEMVTKGQTVPQVNNAVSALSKSVYEKMFLWMVIRI 445
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 446 NEMLD-TKQPRQFFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 504
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H K
Sbjct: 505 KEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLHDQHLGKTAA 564
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIW- 1866
F P ++++HF++VHYAG VDY+ WL KN DPLN++VV L Q S+ +A ++
Sbjct: 565 FQKPKPAKGKAEAHFSLVHYAGTVDYNIVGWLDKNKDPLNDSVVQLYQKSSLKVLAFLYA 624
Query: 1867 ---KDAEFAGICAAEMNETAFGMRSRK--GMFRTVSQLHKEQLTKLMTTLRNTSPHFVRC 2031
+AE G G + +K G F+TVS L +E L KLMT LR+T PHFVRC
Sbjct: 625 THGAEAEGGG-----------GKKGKKKGGSFQTVSALFRENLGKLMTNLRSTHPHFVRC 673
Query: 2032 IIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK 2211
+IPN K G + + LV+ QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L VIP+
Sbjct: 674 LIPNESKTPGLMENYLVIHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASVIPE 733
Query: 2212 -NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQC 2388
FID K++ K++ ++D+D Y+ G +KVFF+ G+L LEE RD KL L+ QA C
Sbjct: 734 GQFIDNKKASEKLLGSIDVDHTQYKFGHTKVFFKAGLLGALEEMRDEKLALLVTMTQALC 793
Query: 2389 RGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAK 2568
RG++ R+ + N +++ +++W W +L+ K+KPLL+ T+ E+ A
Sbjct: 794 RGYVMRKEFVKMMERRESIYSIQYNIRSFMNVKHWPWMKLYFKIKPLLKSAETEKEMAAM 853
Query: 2569 DDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRN 2748
+ KE L K +E E+K+ ++ E+ +Q Q+ ESEN ++ ++ L
Sbjct: 854 KENYEKMKEDLTKALAKKKELEEKMVSLLQEKNDLQLQVTAESENLSDAEERCEGLIKSK 913
Query: 2749 QELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVD 2928
+LE + + +RL +RK + + +K +
Sbjct: 914 IQLEAKLKETNERLEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 973
Query: 2929 QXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLH 3108
++ L E++ KAK +LE Q+
Sbjct: 974 NKVKNLTEEMASQDESIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVD 1033
Query: 3109 ELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLT 3288
+LE L +E++ + +LE+ KRKL +L+ +++ + + + ++ + ++ K+D E+ L+
Sbjct: 1034 DLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDLENEKQQSDEKIKKKDFEISQLLS 1093
Query: 3289 RYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLD 3468
+ ++E + +QK+++++Q I+EL E++E ER AR K E R ++ +LE++ + L+
Sbjct: 1094 KIEDEQSLGAQLQKKIKELQARIEELEEEIEAERAARAKVEKQRADLSRELEEI-SERLE 1152
Query: 3469 KVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHK 3645
+ AT Q M++K E E +R +E+ E + + + V EL +QI+ +
Sbjct: 1153 EAGGATAAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKEQADSVAELGEQIDNLQ 1212
Query: 3646 KQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKR 3825
+ + +LEK++++ E D+ + + ++A+++K + E L EI+ +SDE+ R
Sbjct: 1213 RVKQKLEKEKSEYKMEIDDLTSNMEAVAKAKANLEKMCRTLEDQLSEIK---TKSDENVR 1269
Query: 3826 TLID---QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIA 3996
L D Q R + E +R EE+E + + R + K A
Sbjct: 1270 QLNDMNAQRARLQTENGEFSRQLEEKEALVSQLTRGKQAYTQQIEELKRHIEEEVKAKNA 1329
Query: 3997 NINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRK 4176
+ + + + L ++ EE + +A L++ + A + R K E Q+ EEL +
Sbjct: 1330 LAHAVQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEE 1389
Query: 4177 KNLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKK 4347
+ + LQ E E + + ++K+++Q E+ED +++E + + +K+Q+
Sbjct: 1390 AKKKLAQRLQDAEESIEAVNSKCASLEKTKQRLQGEVEDLMIDVERANSLAANLDKKQRN 1449
Query: 4348 FESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQE 4527
F+ +AE + +++ + + +E R T + + N + +HLE R ++LQQE
Sbjct: 1450 FDKVLAEWKQKYEESQAELEGAQKEARSLSTELFKMKNSYEEALDHLETLKRENKNLQQE 1509
Query: 4528 LQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQAL 4707
+ D + GK++HELEKAK+++E+E ++++ +EE E L+ E LR+++ +
Sbjct: 1510 ISDLTEQLGETGKSIHELEKAKKTVESEKSEIQTALEEAEGTLEHEESKILRVQLELNQV 1569
Query: 4708 KSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQ 4887
KSE DR ++ KD E E+ +R + I +++ L++E R ++ A+ +KK+E + E+E Q
Sbjct: 1570 KSEIDRKLAEKDEEMEQIKRNSQRVIDSMQSTLDSEVRSRNDALRVKKKMEGDLNEMEIQ 1629
Query: 4888 LEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQL 5067
L ANR E + Q+ +EA + +ED+ + +R+ ++AE E+L
Sbjct: 1630 LSHANRQAAEAQKQLRNVQGQLKDAQLHLDEAVRGQEDMKEQVAMVERRNSLMQAEIEEL 1689
Query: 5068 REANEGLMQARKQXXXXXXXXXXXRAKGGGISSEE------KRRLEAKIAQXXXXXXXXQ 5229
R A E + RK + G + S+ K++LEA + Q
Sbjct: 1690 RAALEQTERGRK---VAEQELVDASERVGLLHSQNTSLINTKKKLEADLVQVQGEVDDAV 1746
Query: 5230 SNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQ 5409
A +K +KA + +L E+ + E K++LE + +D + ++ E ES A
Sbjct: 1747 QEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEVTVKDLQHRLDEAESLAM 1806
Query: 5410 SRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAK 5589
+ Q+ LE++V+ LE ++ E + A + R+ E+R+ + T Q E++K+ + +
Sbjct: 1807 KGGKKQLQKLESRVRELEAEVEAEQRRGADAVKGVRKYERRVKELTYQTEEDKKNVIRLQ 1866
Query: 5590 ELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+L++K LK + +RQ +EAE++ + +++R VQ E ++
Sbjct: 1867 DLVDKLQLKVKVYKRQAEEAEEQTNTHLSRYRKVQHELEE 1906
Score = 139 bits (351), Expect = 6e-31
Identities = 166/875 (18%), Positives = 373/875 (41%), Gaps = 26/875 (2%)
Frame = +1
Query: 3166 KRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDM 3345
K LL LE+ +D EK+ + + Q + R ++ + + E ++ +Q +R
Sbjct: 767 KAGLLGALEEMRD---EKLALLVTMT-QALCRGYVMRKEFVKMMERRESIYSIQYNIRSF 822
Query: 3346 QTTIDELREDMETERNARNKAEMTRREVVAQ---LEKVKGDVLDKVDEATMLQD----LM 3504
+ + K+ T +E+ A EK+K D+ + + L++ L+
Sbjct: 823 MNVKHWPWMKLYFKIKPLLKSAETEKEMAAMKENYEKMKEDLTKALAKKKELEEKMVSLL 882
Query: 3505 SRKDE---EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQ 3675
K++ +V A + + EG I+ K + +++E ++++E ++ ++L ++
Sbjct: 883 QEKNDLQLQVTAESENLSDAEERCEGLIKS-KIQLEAKLKETNERLEDEEEINAELTAKK 941
Query: 3676 NQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSR 3855
+ + E +++ ++I L+ + A ++K++ E + + +A DE I +L + +
Sbjct: 942 RKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMASQDES----IAKLTKEK 997
Query: 3856 DELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKN 4035
L ++ ++ A + L A T+L+ +Q++D +
Sbjct: 998 KALQEAHQQTLDDLQAEEDKVNTLTKAK-------------TKLE-------QQVDDLEG 1037
Query: 4036 ALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAE-----ESVNQQLEELRKKNLRDVEH 4200
+L EK+ LR LE+ A R+ G+ + E E+ QQ +E KK ++
Sbjct: 1038 SLEQEKK----LRMDLER---AKRKLEGDLKLAQESIMDLENEKQQSDEKIKKKDFEISQ 1090
Query: 4201 LQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVA 4380
L ++E+ + ++ + K++Q +E+ E+E RA+ EK++ ++ E
Sbjct: 1091 LLSKIEDEQSLGAQLQKKIKELQARIEELEEEIEAERAARAKVEKQRADLSRELEEISER 1150
Query: 4381 VQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEES----DRVRRSLQQELQDSISN 4548
+++A A + + RE E M+ LEES + +L++E DS++
Sbjct: 1151 LEEAGGATAAQIEMNKKREA-------EFQKMRRDLEESTLQHEATAAALRKEQADSVA- 1202
Query: 4549 KDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRA 4728
+ G+ + L++ K+ LE E ++ ++++++L N++ A+ LE + L+ +
Sbjct: 1203 --ELGEQIDNLQRVKQKLEKEKSEYKMEIDDLTSNMEAVAKAKANLEKMCRTLEDQ---- 1256
Query: 4729 ISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRL 4908
+S +++E ++Q+ D+ + R +++ + GE +QLE L
Sbjct: 1257 LSEIKTKSDEN----VRQLNDMN--------------AQRARLQTENGEFSRQLEEKEAL 1298
Query: 4909 KEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA----DRKFRAVEAEREQLREA 5076
+ E + EE +AK +A ++ A D E E+E E
Sbjct: 1299 VSQLTRGKQAYTQQIEELKRHIEEEVKAKNALAHAVQSARHDCDLLREQYEEEQEAKAEL 1358
Query: 5077 NEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDK 5256
G+ +A + + E K++L ++ S C
Sbjct: 1359 QRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEESIEAVNSKCASLEKT 1418
Query: 5257 QRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES---GAQSRARAQ 5427
+++ Q ++E + D+ +L + ++++ ++ ++K K E ++ GAQ AR+
Sbjct: 1419 KQRLQGEVEDLMIDVERANSLAANLDKKQRNFDKVLAEWKQKYEESQAELEGAQKEARSL 1478
Query: 5428 MAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKS 5607
L E+ L+ R + L++ ++D T+Q + ++ + ++ +
Sbjct: 1479 STELFKMKNSYEEALD----HLETLKRENKNLQQEISDLTEQLGETGKSIHELEKAKKTV 1534
Query: 5608 NLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ ++ L+EAE + E +K VQ E + +
Sbjct: 1535 ESEKSEIQTALEEAEGTLEHEESKILRVQLELNQV 1569
Score = 126 bits (317), Expect = 6e-27
Identities = 179/911 (19%), Positives = 372/911 (40%), Gaps = 125/911 (13%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ +E ++ +E++ +++++K+ + E + + +++ E A+L LQ
Sbjct: 1054 RKLEGDLKLAQESIMDLENEKQQSDEKIKKKDFEISQLLSKIEDEQSLGAQLQKKIKELQ 1113
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + R +++E + + +
Sbjct: 1114 ARIEELEEEIEAER----AARAKVEKQRADLSRELEEISERLEEAGGATAAQIEMNKKRE 1169
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K +
Sbjct: 1170 AEFQKMRRDLEESTLQHEATAAALRKEQADSVAELG---EQIDNLQRVKQKLEKEKSEYK 1226
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K+ LE+ R L +L + K E + ++ ++N Q + E
Sbjct: 1227 MEIDDLTSNMEAVAKAKANLEKMCRTLEDQLSEIKTKSDENVRQLNDMNAQRARLQTENG 1286
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ +E+ A V+ + + + I+EL+ +E E A+N + + ++
Sbjct: 1287 EFSRQLEEKEALVSQLTRGKQAYTQQIEELKRHIEEEVKAKNALAHAVQSARHDCDLLRE 1346
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
++ + LQ MS+ + EV TK + IQ T E +EE K K ++++++ +
Sbjct: 1347 QYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQDAEES 1404
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME-------I 3789
IE + + LEK + + E D+ ++ + A++DKK++ + L E
Sbjct: 1405 IEAVNSKCASLEKTKQRLQGEVEDLMIDVERANSLAANLDKKQRNFDKVLAEWKQKYEES 1464
Query: 3790 QANLAESDEHKRTLIDQLERSRDE----LDHLNRVREEEEHAFANMQRRLATAXXXXXXX 3957
QA L + + R+L +L + ++ LDHL ++ E + N+Q+ ++
Sbjct: 1465 QAELEGAQKEARSLSTELFKMKNSYEEALDHLETLKRENK----NLQQEISDLTEQLGE- 1519
Query: 3958 XXXXXXXTRLKIANINRARQ-LEDEKNALLDEKEEAEGLRAHLEKEIHAAR----QGAGE 4122
T I + +A++ +E EK+ + EEAEG H E +I + Q E
Sbjct: 1520 -------TGKSIHELEKAKKTVESEKSEIQTALEEAEGTLEHEESKILRVQLELNQVKSE 1572
Query: 4123 ARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
RK E ++++E++++ + R ++ +Q L+ ++ L+ KKK++ +L + ++L
Sbjct: 1573 IDRKLAEK-DEEMEQIKRNSQRVIDSMQSTLDSEVRSRNDALRVKKKMEGDLNEMEIQLS 1631
Query: 4303 --------------NVRASHRDS---------------------EKRQKKFESQMAEERV 4377
NV+ +D+ E+R ++++ E R
Sbjct: 1632 HANRQAAEAQKQLRNVQGQLKDAQLHLDEAVRGQEDMKEQVAMVERRNSLMQAEIEELRA 1691
Query: 4378 AVQKALLDRDAMSQELRDRETRV-------LSLLN-----EVDIMKEHLEESDRVR--RS 4515
A+++ R QEL D RV SL+N E D+++ E D V+ R+
Sbjct: 1692 ALEQTERGRKVAEQELVDASERVGLLHSQNTSLINTKKKLEADLVQVQGEVDDAVQEARN 1751
Query: 4516 LQQELQDSISN--------KDDFGKNVHELEKAKRSLEAELNDMRVQMEELED------- 4650
+++ + +I++ K + + H LE+ K++LE + D++ +++E E
Sbjct: 1752 AEEKAKKAITDAAMMAEELKKEQDTSAH-LERMKKNLEVTVKDLQHRLDEAESLAMKGGK 1810
Query: 4651 -NLQIAEDARLRLEVTNQA-----------------------LKSESDR--AISNKDV-- 4746
LQ E LE +A ++E D+ I +D+
Sbjct: 1811 KQLQKLESRVRELEAEVEAEQRRGADAVKGVRKYERRVKELTYQTEEDKKNVIRLQDLVD 1870
Query: 4747 --------------EAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQ 4884
EAEE+ L + R +++ELE + A E+Q+ +L
Sbjct: 1871 KLQLKVKVYKRQAEEAEEQTNTHLSRYRKVQHELEEAQERADVA-------ESQVNKLRA 1923
Query: 4885 QLEVANRLKEE 4917
+ A + K+E
Sbjct: 1924 KSRDAGKSKDE 1934
Score = 69.3 bits (168), Expect = 1e-09
Identities = 100/463 (21%), Positives = 192/463 (40%), Gaps = 36/463 (7%)
Frame = +1
Query: 4462 EVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE 4641
E+ MKE+ E+ ++++L +++ K ELE+ SL E ND+++Q+
Sbjct: 849 EMAAMKENYEK-------MKEDLTKALAKKK-------ELEEKMVSLLQEKNDLQLQVTA 894
Query: 4642 LEDNLQIAED-------ARLRLEV----TNQALKSESD--RAISNKDVEAEEKRRGLLKQ 4782
+NL AE+ ++++LE TN+ L+ E + ++ K + E++ L K
Sbjct: 895 ESENLSDAEERCEGLIKSKIQLEAKLKETNERLEDEEEINAELTAKKRKLEDECSELKKD 954
Query: 4783 IRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEY 4962
I DLE L ++ K K++N E+ Q E +L +E +
Sbjct: 955 IDDLELTLAKVEKEKHAT---ENKVKNLTEEMASQDESIAKLTKEKKALQEAHQQTLDDL 1011
Query: 4963 QIECEEARQAKEDIAALLREADRKFRAVEAERE---QLREANEGLMQARKQXXXXXXXXX 5133
Q E ++ + L ++ D ++E E++ L A L K
Sbjct: 1012 QAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDLE 1071
Query: 5134 XXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMER 5313
+ + S E+ ++ + +I+Q QS K ++ Q ++E++ ++ ER
Sbjct: 1072 NEKQQ----SDEKIKKKDFEISQLLSKIEDEQSLGAQLQKKIKELQARIEELEEEIEAER 1127
Query: 5314 TLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQM-AALEAKVQYLEDQLNVEGQE 5490
K E ++ L R + ++ E +G + A+ +M EA+ Q + L +E
Sbjct: 1128 AARAKVEKQRADLSRELEEISERLEE--AGGATAAQIEMNKKREAEFQKMRRDL----EE 1181
Query: 5491 KTAANRA-ARRLEKRLNDTTQQFEDEKRANEQAKELLEK-------------SNLK---- 5616
T + A A L K D+ + ++ ++ K+ LEK SN++
Sbjct: 1182 STLQHEATAAALRKEQADSVAELGEQIDNLQRVKQKLEKEKSEYKMEIDDLTSNMEAVAK 1241
Query: 5617 -NRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
NL + ED++S +TK R+ +D+ +L E
Sbjct: 1242 AKANLEKMCRTLEDQLSEIKTKSDENVRQLNDMNAQRARLQTE 1284
>gi|4505301|ref|NP_002463.1| myosin, heavy polypeptide 8, skeletal
muscle, perinatal [Homo sapiens]
gi|189034|gb|AAC17185.1| perinatal myosin heavy chain [Homo sapiens]
Length = 1937
Score = 1103 bits (2852), Expect = 0.0
Identities = 641/1889 (33%), Positives = 1050/1889 (54%), Gaps = 15/1889 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V + E ++ +I+ + +V V+ + +T+ D V NPPK+DKIEDM+ +T+L
Sbjct: 41 FVAEPKESYVKSTIQSKEGGKVTVK-TEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHL 99
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y +++ ++GKKR E PPHIF+
Sbjct: 100 HEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFS 159
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A K + Q
Sbjct: 160 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKDESGKMQ--- 216
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 217 ---------GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIE 267
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPNV 981
YLLEKSRV Q + ERS+HIFYQI + E LL + +Y F+ IT+P++
Sbjct: 268 TYLLEKSRVTFQLKAERSYHIFYQITSN-KKPDLIEMLLITTNPYDYAFVSQGEITVPSI 326
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
DD +E +T +++ I+GF +E SI ++ AV+ GN++F Q+++ +QA V K
Sbjct: 327 DDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADK 386
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L L +L KA PR+KVG E+V K Q +Q AV A+AKA YE++F W+VTRI
Sbjct: 387 AAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRI 446
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 447 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW FIDFG+DL I+LIEKP+G+ ++L+EEC+FPKA D SF KL H K
Sbjct: 506 KEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSFKNKLYDQHLGKSAN 565
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P + ++++HF+++HYAG VDY+ WL KN DPLN+ VVGL Q S +A +
Sbjct: 566 FQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASL-- 623
Query: 1870 DAEFAGICAAEMNETA-FGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNH 2046
F+ +AE + +A G + + F+TVS L +E L KLMT LR+T PHFVRCIIPN
Sbjct: 624 ---FSTYASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNE 680
Query: 2047 EKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFID 2223
K G + LVL QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L IP+ FID
Sbjct: 681 TKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQFID 740
Query: 2224 GKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLS 2403
K++ K++ ++DID Y+ G +KVFF+ G+L LEE RD KL +I QA CRGFL
Sbjct: 741 SKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFLM 800
Query: 2404 RRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELR 2583
R Y N A++ +++W W +LF K+KPLL+ T+ E+ +E +
Sbjct: 801 RVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQ 860
Query: 2584 ATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEY 2763
TK+ L K E +E E+K+ ++ E+ +Q Q+Q E+++ A+ ++ +L +LE
Sbjct: 861 KTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEA 920
Query: 2764 IVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXX 2943
+ ++ +R +RK + + K +
Sbjct: 921 KIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKQKHATENKVKN 980
Query: 2944 XXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQD 3123
+ L E++ KAK +LE Q+ +LE
Sbjct: 981 LTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGS 1040
Query: 3124 LNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEE 3303
L +E++ + +LE+ KRKL +L+ +++ + ++L+ +L K++ E+ + +++ ++E
Sbjct: 1041 LEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDE 1100
Query: 3304 SANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEA 3483
A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L++ A
Sbjct: 1101 QAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEI-SERLEEAGGA 1159
Query: 3484 TMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQ 3660
T Q +L +++ E +R +E+ E + + K + + EL +QI+ ++ + +
Sbjct: 1160 TSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQK 1219
Query: 3661 LEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQ 3840
LEK++++ E D++ + ++ ++K + E + ++ E L Q
Sbjct: 1220 LEKEKSELKMETDDLSSNAEAISKAKGHLEKMCRSLEDQVSGLKTKEEEQQRLINDLTAQ 1279
Query: 3841 LERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQL 4020
R + E +R +E++ + + R + T+ K A + +
Sbjct: 1280 RARLQTEAGEYSRQLDEQDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSS 1339
Query: 4021 EDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEH 4200
+ + L ++ EE + +A L++ + A + R K E Q+ EEL + + +
Sbjct: 1340 RHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1399
Query: 4201 LQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEE 4371
LQ+ E E + + ++K+++Q E+ED +++E A+ +K+Q+ F+ ++E
Sbjct: 1400 LQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEW 1459
Query: 4372 RVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNK 4551
+ ++ + +A +E R T + + N + + LE R ++LQQE+ D
Sbjct: 1460 KQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRAHKNLQQEISDLTEQI 1519
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAI 4731
+ GK +HELEK K+ +E E +++ +EE E +L+ E LR+++ +KSE DR I
Sbjct: 1520 AEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKI 1579
Query: 4732 SNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLK 4911
+ KD E ++ +R + + +++ L+ E R ++ A+ +KK+E + E+E QL ANRL
Sbjct: 1580 AEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLA 1639
Query: 4912 EEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLM 5091
E E Q+ ++A + +ED+ L +R+ ++AE E+L E
Sbjct: 1640 AESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTE 1699
Query: 5092 QARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQR 5262
++RK Q K++LE ++Q A +K +
Sbjct: 1700 RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAK 1759
Query: 5263 KAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALE 5442
KA + +L E+ + E K++LE++ +D + ++ E E A + Q+ LE
Sbjct: 1760 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1819
Query: 5443 AKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNR 5622
A+V+ LE ++ E + A + R+ ++R+ + T Q E++++ + ++L++K K +
Sbjct: 1820 ARVRELEGEVENEQKRNAEAVKGLRKHDRRVKELTYQTEEDRKNVLRLQDLVDKLQAKVK 1879
Query: 5623 NLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+ +RQ +EAE++ + +K R +Q E ++
Sbjct: 1880 SYKRQAEEAEEQSNANLSKFRKLQHELEE 1908
Score = 169 bits (428), Expect = 7e-40
Identities = 189/959 (19%), Positives = 417/959 (42%), Gaps = 61/959 (6%)
Frame = +1
Query: 3040 LLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKL-------------- 3177
L D EER + +K K +LE ++ E+ + E + +EL KRKL
Sbjct: 901 LADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDL 960
Query: 3178 ---LAELEDSK-------DHLAEKMGKVEELNNQLMKRDEELQ--HQLTRYD--EESANV 3315
LA++E K +L E+M ++E +L K + LQ HQ T D E V
Sbjct: 961 ELTLAKVEKQKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKV 1020
Query: 3316 TLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ 3495
++ K ++ +D+L +E E+ R E +R++ L+ + +D ++ L
Sbjct: 1021 NILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLD 1080
Query: 3496 DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQ 3675
+ + +K+ E++ IE + +E +++++ + ++EEL ++IE + R++ EKQ+
Sbjct: 1081 EKLEKKEFEISNLISKIED-EQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQR 1139
Query: 3676 NQADQERADMA---QEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLI---- 3834
+ +E +++ +E +++ +++KKR EA +++ +L E+ ++
Sbjct: 1140 SDLSRELEEISERLEEAGGATSAQVELNKKR---EAEFQKLRRDLEEATLQHEAMVAALR 1196
Query: 3835 ----DQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANI 4002
D + +++D+L RV+++ E + ++ ++
Sbjct: 1197 KKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGHLEKM----- 1251
Query: 4003 NRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEE--SVNQQLEELRK 4176
R LED+ + L ++EE + L L + + AGE R+ +E ++ QL ++
Sbjct: 1252 --CRSLEDQVSGLKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEQDALVSQLSRSKQ 1309
Query: 4177 KNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFES 4356
+ + +E L+ QLEE AK + + + + + + + E + + ++ K S
Sbjct: 1310 ASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANS 1369
Query: 4357 QMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLE-------ESDRVRRS 4515
++A+ R + + R ++EL + + ++ L E + EH+E ++ ++
Sbjct: 1370 EVAQWRTKYETDAIQR---TEELEEAKKKLAQRLQEAE---EHVEAVNAKCASLEKTKQR 1423
Query: 4516 LQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVT 4695
LQ E++D + + + L+K +R+ + L++ + + EE + L+ ++ L
Sbjct: 1424 LQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTE 1483
Query: 4696 NQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGE 4875
+K+ + ++ + + L ++I DL ++ + +K++E + E
Sbjct: 1484 LFKVKNVYEESLDQLET-LRRAHKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCE 1542
Query: 4876 LEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEAR--QAKEDIAALLREADRKFRAVE 5049
++ LE A E +E EE + + + ++ + E DRK +
Sbjct: 1543 IQAALEEA-------------------EASLEHEEGKILRIQLELNQVKSEVDRKIAEKD 1583
Query: 5050 AEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQ 5229
E +QL+ + +++ + R++ + K+++E + +
Sbjct: 1584 EEIDQLKRNHTRVVETMQ-----STLDAEIRSRNDAL--RVKKKMEGDLNEMEIQLNHAN 1636
Query: 5230 SNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQ--SLERSNRDYKAKITE---- 5391
++ R Q L++ T L ++ L + + ++Q +ER +A+I E
Sbjct: 1637 RLAAESLRNYRNTQGILKE--TQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWAT 1694
Query: 5392 LESGAQSRARAQMAALEA--KVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDE 5565
LE +SR A+ L+A +VQ L Q T+ ++LE ++ + E+
Sbjct: 1695 LEQTERSRKIAEQELLDASERVQLLHTQ-------NTSLINTKKKLENDVSQLQSEVEEV 1747
Query: 5566 KRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL---LDANEQL 5733
+ + A+E +K+ + +L + +D + +N+++ DL LD EQL
Sbjct: 1748 IQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQL 1806
Score = 117 bits (292), Expect = 4e-24
Identities = 180/910 (19%), Positives = 359/910 (38%), Gaps = 133/910 (14%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ +E + ME+D ++ ++KL++ E + + ++ E E + E+ +LQ
Sbjct: 1056 RKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKI--EDEQAVEI-----QLQ 1108
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRR---KQMETVRDXXXXXXXXXXXXXXXXX 2910
+ +EL+ + ++ + + R +++E + +
Sbjct: 1109 KKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNK 1168
Query: 2911 DKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGR 3090
+ Q +A G + +D+ +R K +
Sbjct: 1169 KREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELG---EQIDNLQRVKQ------K 1219
Query: 3091 LENQLHELEQ---DLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKR 3261
LE + EL+ DL+ + S+ + H K+ LED L K + + L N L +
Sbjct: 1220 LEKEKSELKMETDDLSSNAEAISKAKGHLEKMCRSLEDQVSGLKTKEEEQQRLINDLTAQ 1279
Query: 3262 DEELQHQLTRY----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREV 3429
LQ + Y DE+ A V+ + + + I+EL+ +E E A+N +
Sbjct: 1280 RARLQTEAGEYSRQLDEQDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSS 1339
Query: 3430 VAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFS 3603
+ ++ ++ + LQ +S+ + EV TK + IQ T E +EE K K +
Sbjct: 1340 RHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLA 1397
Query: 3604 RQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLM 3783
++++E + +E + + LEK + + E D+ ++ A+ A +DKK++ + L
Sbjct: 1398 QRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLS 1457
Query: 3784 E-------IQANLAESDEHKRTL--------------IDQLERSR--------------- 3855
E QA L S + R+L +DQLE R
Sbjct: 1458 EWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRAHKNLQQEISDLTE 1517
Query: 3856 ------DELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQ 4017
++ L +++++ E +Q L A R+++ +N+ +
Sbjct: 1518 QIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKIL---RIQL-ELNQVKS 1573
Query: 4018 LEDEKNALLDEKEE---------AEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEEL 4170
D K A DE+ + E +++ L+ EI + R A ++K E +N+ +L
Sbjct: 1574 EVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRS-RNDALRVKKKMEGDLNEMEIQL 1632
Query: 4171 RKKN---------------------------LRDVEHLQKQL--------------EESE 4227
N LR E L++QL EE
Sbjct: 1633 NHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELW 1692
Query: 4228 VAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRD 4407
E+ +S+K +QEL D+S ++ + + +KK E+ +++ + V++ +
Sbjct: 1693 ATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVI---- 1748
Query: 4408 AMSQELRDRETRVLSLLNEVDIMKEHLEES-------DRVRRSLQQELQDSISNKDDFG- 4563
QE R+ E + + + +M E L++ +R++++L+Q ++D D+
Sbjct: 1749 ---QESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQ 1805
Query: 4564 -------KNVHELEKAKRSLEAELNDMRVQMEELEDNL------------QIAEDAR--L 4680
K + +LE R LE E+ + + + E L Q ED + L
Sbjct: 1806 LALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHDRRVKELTYQTEEDRKNVL 1865
Query: 4681 RLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIE 4860
RL+ L+++ ++ + EAEE+ L + R L++ELE + A S K+
Sbjct: 1866 RLQDLVDKLQAKV-KSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLR 1924
Query: 4861 NQIGELEQQL 4890
+ E+ ++
Sbjct: 1925 VKSREVHTKI 1934
Score = 93.2 bits (230), Expect = 7e-17
Identities = 89/449 (19%), Positives = 192/449 (41%), Gaps = 20/449 (4%)
Frame = +1
Query: 3100 QLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQH 3279
Q+HELE+ K ++EQ K ++ A LE+++ L + GK+ + +L + E+
Sbjct: 1525 QIHELEK-------IKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1577
Query: 3280 QLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGD 3459
++ DEE + + R+ ++ ++ ++ E +RN A ++ K++GD
Sbjct: 1578 KIAEKDEE------IDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKK-------KMEGD 1624
Query: 3460 VLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKI------EEQKAKFSRQVEEL 3621
+ + + L + T+ +++ Q ++ + +EQ A R+ L
Sbjct: 1625 LNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLL 1684
Query: 3622 HDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL 3801
+IE+ Q E+ + A+QE D ++ + LL + +K E + ++Q+ +
Sbjct: 1685 QAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEV 1744
Query: 3802 AESDEHKRT--------------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAX 3939
E + R + ++L++ +D HL R+++ E ++Q RL A
Sbjct: 1745 EEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAE 1804
Query: 3940 XXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAG 4119
++ + + E ++NA E +GLR H ++ +
Sbjct: 1805 QLALKGGKKQIQKLEARVRELEGEVENEQKRNA-----EAVKGLRKH-DRRVKELTYQTE 1858
Query: 4120 EARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMEL 4299
E R+ +L++L K V+ ++Q EE+E L +K+Q ELE++
Sbjct: 1859 EDRKNV-----LRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEA---- 1909
Query: 4300 ENVRASHRDSEKRQKKFESQMAEERVAVQ 4386
RA +S+ + + +S+ +++ +
Sbjct: 1910 -EERADIAESQVNKLRVKSREVHTKISAE 1937
Score = 76.6 bits (187), Expect = 7e-12
Identities = 76/389 (19%), Positives = 169/389 (42%), Gaps = 25/389 (6%)
Frame = +1
Query: 4654 LQIAEDARLRLEVTNQALKSESDRAISN-KDVEAEEKRRGLLKQIRDLENELENEKRGKS 4830
L+ AE + + + K++ + A S K E EEK LLK+ DL+ ++++E +
Sbjct: 843 LKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLA 902
Query: 4831 GAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAA 5010
A +++ +LE +++ EE + + EC E ++ +D+
Sbjct: 903 DAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLEL 962
Query: 5011 LLREADRKFRAVEAEREQLREANEGL----------MQARKQXXXXXXXXXXXRAKGGGI 5160
L + +++ A E + + L E GL +A ++ I
Sbjct: 963 TLAKVEKQKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNI 1022
Query: 5161 SSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLE----QITTDLSMERTLNQK 5328
++ K +LE ++ + E ++++++K ++ LE ++ DL + +
Sbjct: 1023 LTKAKTKLEQQV-----------DDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMD 1071
Query: 5329 TEAEKQSLERSNRDYKAKITEL------ESGAQSRARAQMAALEAKVQYLEDQLNVEGQE 5490
E +KQ L+ + +I+ L E + + + ++ L+A+++ L +++ E
Sbjct: 1072 MENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERAS 1131
Query: 5491 KTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEA----EDE 5658
+ A + L + L + +++ E+ A EL +K + + LRR L+EA E
Sbjct: 1132 RAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAM 1191
Query: 5659 MSRERTKHRNVQREADDLLDANEQLTREL 5745
++ R KH + E + +D +++ ++L
Sbjct: 1192 VAALRKKHADSMAELGEQIDNLQRVKQKL 1220
>gi|50512294|ref|NP_694514.2| myosin, heavy polypeptide 2, fast muscle
specific [Danio rerio]
gi|48734671|gb|AAH71279.1| Myosin, heavy polypeptide 2, fast muscle
specific [Danio rerio]
Length = 1935
Score = 1102 bits (2850), Expect = 0.0
Identities = 646/1897 (34%), Positives = 1049/1897 (55%), Gaps = 22/1897 (1%)
Frame = +1
Query: 85 CWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTY 264
C+V D E ++ G+IK + +V V +DT + + DDV NPPKFDKIEDM+ +T+
Sbjct: 38 CYVVDDKELYVKGTIKSKDGGKVTVVTLDTQTEKVVKEDDVHPMNPPKFDKIEDMAMMTH 97
Query: 265 LNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIF 444
LNE SVL+NLK+RY + +IYTYSGLFC +NPYK LP+Y +++ ++GKKR E PPHIF
Sbjct: 98 LNEPSVLYNLKERYAAWMIYTYSGLFCATVNPYKWLPVYDAEVVAAYRGKKRMEAPPHIF 157
Query: 445 AIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVA--GATRNKSLNAAAQQ 618
+++D AY+ ML +RE+QS+L TGESGAGKT NTK+VIQY A VA G + K A Q
Sbjct: 158 SVSDNAYQFMLTDRENQSVLITGESGAGKTVNTKRVIQYFATVAVQGGDKKKEQAAGKMQ 217
Query: 619 NIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGA 798
G LE Q++ ANP+LEA+GN+KTV+NDNSSRFGKFIRI+F SG ++ A
Sbjct: 218 ------------GSLEDQIIAANPLLEAYGNAKTVRNDNSSRFGKFIRIHFGTSGKLASA 265
Query: 799 NIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRF-LVNRG-ITL 972
+IE YLLEKSRV Q DER +HIFYQ++ E E L + Y F + ++G IT+
Sbjct: 266 DIETYLLEKSRVTFQLPDERGYHIFYQMMTN-HKPELIEMTLITTNPYDFPMCSQGQITV 324
Query: 973 PNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRV 1152
++DD +E +T ++ I+GF +E I + AVL GN++F Q+++ +QA
Sbjct: 325 ASIDDKEELVATDTAIDILGFTGEEKMGIYKFTGAVLHHGNMKFKQKQREEQAEPDGTEE 384
Query: 1153 IQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLV 1332
K+ +LLGL ++ KA PR+KVG EFV K Q Q +V A++K+ YER+F W+V
Sbjct: 385 ADKIAYLLGLNSADMLKALCYPRVKVGNEFVTKGQTVPQVYNSVSALSKSIYERMFLWMV 444
Query: 1333 TRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQE 1512
RIN+ LD T +Q FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQE
Sbjct: 445 IRINQMLD-TKQQRNFFIGVLDIAGFEIFDFNSMEQLCINFTNEKLQQFFNHHMFVLEQE 503
Query: 1513 EYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH--- 1683
EY++EGI W+FIDFG+DL I+LIEKP+G+ ++L+EEC+FPKA D SF KL H
Sbjct: 504 EYKKEGIVWEFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSFKNKLYDQHLGK 563
Query: 1684 -NKHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAG 1860
N K ++++HF++VHYAG VDY+ WL KN DPLNE+VV L Q S+ +A
Sbjct: 564 CNAFQKPKPAKGKAEAHFSLVHYAGTVDYNISGWLDKNKDPLNESVVQLYQKSSVKLLAT 623
Query: 1861 IWKDAEFAGICAAEMNETAFGMRSRK---GMFRTVSQLHKEQLTKLMTTLRNTSPHFVRC 2031
++ + ET G + K G +TVS +E L KLMT LR+T PHFVRC
Sbjct: 624 LYPPV---------VEETGGGKKGGKKKGGSMQTVSSQFRENLGKLMTNLRSTHPHFVRC 674
Query: 2032 IIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK 2211
+IPN K G + + LV+ QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L VIP+
Sbjct: 675 LIPNESKTPGLMENFLVIHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASVIPE 734
Query: 2212 -NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQC 2388
FID K++ K++ ++D++ + YR G +KVFF+ G+L LEE RD KL L+ QA C
Sbjct: 735 GQFIDNKKASEKLLGSIDVNHDEYRFGHTKVFFKAGLLGTLEEMRDEKLATLVTMTQALC 794
Query: 2389 RGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAK 2568
R +L RR + N +++ +++W W +++ K+KPLL+ T+ E+
Sbjct: 795 RAYLMRREFVKMMERRESIYTIQYNIRSFMNVKHWPWMKVYYKIKPLLKSAETEKELATM 854
Query: 2569 DDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRN 2748
++ KE L K E +E E+K+ ++ E+ +Q + ESEN ++ ++ L
Sbjct: 855 KEDFVKCKEALAKAEAKKKELEEKMVALLQEKNDLQLAVASESENLSDAEERCEGLIKSK 914
Query: 2749 QELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVD 2928
+LE + + +RL +RK + + +K +
Sbjct: 915 IQLEAKLKETTERLEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 974
Query: 2929 QXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLH 3108
++ L E++ K+K +LE Q+
Sbjct: 975 NKVKNLTEEMASQDESIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKSKTKLEQQVD 1034
Query: 3109 ELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLT 3288
+LE L +E++ + +LE+ KRKL +L+ +++ + + ++ ++ K+D E L+
Sbjct: 1035 DLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDLENDKQQSEEKIKKKDFETAQLLS 1094
Query: 3289 RYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLD 3468
+ ++E + +QK+++++Q I+EL E++E ER AR K E R ++ +LE++ + L+
Sbjct: 1095 KIEDEQSLGAQLQKKIKELQARIEELEEEIEAERAARAKVEKQRADLSRELEEI-SERLE 1153
Query: 3469 KVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHK 3645
+ AT Q M++K E E +R +E+ E + K + V EL +QI+ +
Sbjct: 1154 EAGGATAAQIEMNKKREAEFQKLRRDLEESTLQHEATAAALRKKQADSVAELGEQIDNLQ 1213
Query: 3646 KQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKR 3825
+ + +LEK++++ E D++ + + ++A+++K + E L EI++ E+
Sbjct: 1214 RVKQKLEKEKSEYKMEIDDLSSNMEAVAKAKANLEKMCRTVEDQLSEIKSKNDENLRQIN 1273
Query: 3826 TLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANIN 4005
L Q R + E R EE+E + + R + K A +
Sbjct: 1274 DLSAQRARLQTENGEFGRQLEEKEALVSQLTRGKQAFTQQIEELKRQIEEEVKAKNALAH 1333
Query: 4006 RARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNL 4185
+ + + L ++ EE + +A L++ + A + R K E Q+ EEL +
Sbjct: 1334 AVQSARHDCDLLREQFEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEESKK 1393
Query: 4186 RDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFES 4356
+ + LQ+ E+ E + + ++K+++Q E+ED +++E A + +K+Q+ F+
Sbjct: 1394 KLAQRLQEAEEQIEAVNSKCASLEKTKQRLQGEVEDLMIDVERANALAANLDKKQRNFDK 1453
Query: 4357 QMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQD 4536
+AE + ++ + + +E R T + + N + + LE R ++LQQE+ D
Sbjct: 1454 VLAEWKQKYEEGQAELEGAQKEARSLSTELFKMKNSYEETLDQLETLKRENKNLQQEISD 1513
Query: 4537 SISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSE 4716
+ GK++HELEKAK+++E E +++ +EE E L+ E LR+++ +K E
Sbjct: 1514 LTEQLGETGKSIHELEKAKKTVETEKAEIQTALEEAEGTLEHEESKILRVQLELNQVKGE 1573
Query: 4717 SDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEV 4896
DR ++ KD E E+ +R + +++ L++E R ++ A+ +KK+E + E+E QL
Sbjct: 1574 IDRKLAEKDEEMEQIKRNSQRVTEAMQSTLDSEVRSRNDALRIKKKMEGDLNEMEIQLSH 1633
Query: 4897 ANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREA 5076
ANR E + Q+ ++A + +ED+ + +R+ +++E E+LR A
Sbjct: 1634 ANRQAAEAQKQLRNVQAQLKDAQLHLDDAVRGQEDMKEQVAMVERRNTLMQSEIEELRAA 1693
Query: 5077 NEGLMQARKQXXXXXXXXXXXRAKGGGISSEE------KRRLEAKIAQXXXXXXXXQSNC 5238
E + RK + G + S+ K++LE + Q
Sbjct: 1694 LEQTERGRK---VAEQELVDASERVGLLHSQNTSLLNTKKKLETDLVQIQSEVEDTVQEA 1750
Query: 5239 ELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRA 5418
A +K +KA + +L E+ + E K++LE + +D + ++ E E+ A
Sbjct: 1751 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEVTVKDLQHRLDEAENLAMKGG 1810
Query: 5419 RAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELL 5598
+ Q+ LE++V+ LE ++ E + A + R+ E+R+ + T Q E++K+ + ++L+
Sbjct: 1811 KKQLQKLESRVRELESEVEAEQRRGADAVKGVRKYERRVKELTYQTEEDKKNVNRLQDLV 1870
Query: 5599 EKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+K LK + +RQ +EAE++ + +K R VQ E ++
Sbjct: 1871 DKLQLKVKAYKRQSEEAEEQANSHLSKLRKVQHELEE 1907
Score = 140 bits (354), Expect = 3e-31
Identities = 188/914 (20%), Positives = 370/914 (39%), Gaps = 128/914 (14%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ +E ++ +E+D +++E+K+ + E A + +++ E A+L LQ
Sbjct: 1055 RKLEGDLKLAQESIMDLENDKQQSEEKIKKKDFETAQLLSKIEDEQSLGAQLQKKIKELQ 1114
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + R +++E + + +
Sbjct: 1115 ARIEELEEEIEAER----AARAKVEKQRADLSRELEEISERLEEAGGATAAQIEMNKKRE 1170
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K +
Sbjct: 1171 AEFQKLRRDLEESTLQHEATAAALRKKQADSVAELG---EQIDNLQRVKQKLEKEKSEYK 1227
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K+ LE+ R + +L + K E + ++ +L+ Q + E
Sbjct: 1228 MEIDDLSSNMEAVAKAKANLEKMCRTVEDQLSEIKSKNDENLRQINDLSAQRARLQTENG 1287
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ +E+ A V+ + + + I+EL+ +E E A+N + + ++
Sbjct: 1288 EFGRQLEEKEALVSQLTRGKQAFTQQIEELKRQIEEEVKAKNALAHAVQSARHDCDLLRE 1347
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
++ + LQ MS+ + EV TK + IQ T E +EE K K +++++E +Q
Sbjct: 1348 QFEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEE--LEESKKKLAQRLQEAEEQ 1405
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEI------- 3789
IE + + LEK + + E D+ ++ A A++DKK++ + L E
Sbjct: 1406 IEAVNSKCASLEKTKQRLQGEVEDLMIDVERANALAANLDKKQRNFDKVLAEWKQKYEEG 1465
Query: 3790 QANLAESDEHKRTLIDQL-------ERSRDELDHLNRVREEEEHAFANMQRRLATAXXXX 3948
QA L + + R+L +L E + D+L+ L R + + +++ +L
Sbjct: 1466 QAELEGAQKEARSLSTELFKMKNSYEETLDQLETLKRENKNLQQEISDLTEQLGE----- 1520
Query: 3949 XXXXXXXXXXTRLKIANINRARQ-LEDEKNALLDEKEEAEGLRAHLEKEIHAAR----QG 4113
T I + +A++ +E EK + EEAEG H E +I + Q
Sbjct: 1521 ----------TGKSIHELEKAKKTVETEKAEIQTALEEAEGTLEHEESKILRVQLELNQV 1570
Query: 4114 AGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSM 4293
GE RK E ++++E++++ + R E +Q L+ ++ L+ KKK++ +L + +
Sbjct: 1571 KGEIDRKLAEK-DEEMEQIKRNSQRVTEAMQSTLDSEVRSRNDALRIKKKMEGDLNEMEI 1629
Query: 4294 ELE--------------NVRASHRDS---------------------EKRQKKFESQMAE 4368
+L NV+A +D+ E+R +S++ E
Sbjct: 1630 QLSHANRQAAEAQKQLRNVQAQLKDAQLHLDDAVRGQEDMKEQVAMVERRNTLMQSEIEE 1689
Query: 4369 ERVAVQKALLDRDAMSQELRDRETRV-------LSLLN-----EVDIMKEHLEESDRVR- 4509
R A+++ R QEL D RV SLLN E D+++ E D V+
Sbjct: 1690 LRAALEQTERGRKVAEQELVDASERVGLLHSQNTSLLNTKKKLETDLVQIQSEVEDTVQE 1749
Query: 4510 -RSLQQELQDSISN--------KDDFGKNVHELEKAKRSLEAELNDMRVQMEELED---- 4650
R+ +++ + +I++ K + + H LE+ K++LE + D++ +++E E+
Sbjct: 1750 ARNAEEKAKKAITDAAMMAEELKKEQDTSAH-LERMKKNLEVTVKDLQHRLDEAENLAMK 1808
Query: 4651 ----NLQIAEDARLRLE-----------------------VTNQALKSESDR-------- 4725
LQ E LE V ++E D+
Sbjct: 1809 GGKKQLQKLESRVRELESEVEAEQRRGADAVKGVRKYERRVKELTYQTEEDKKNVNRLQD 1868
Query: 4726 ----------AISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGE 4875
A + EAEE+ L ++R +++ELE + A E+Q+ +
Sbjct: 1869 LVDKLQLKVKAYKRQSEEAEEQANSHLSKLRKVQHELEEAEERADIA-------ESQVNK 1921
Query: 4876 LEQQLEVANRLKEE 4917
L + A + KEE
Sbjct: 1922 LRAKSRDAGKAKEE 1935
Score = 139 bits (351), Expect = 6e-31
Identities = 167/876 (19%), Positives = 368/876 (41%), Gaps = 27/876 (3%)
Frame = +1
Query: 3166 KRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDM 3345
K LL LE+ +D EK+ + + Q + R ++ + + E ++ +Q +R
Sbjct: 768 KAGLLGTLEEMRD---EKLATLVTMT-QALCRAYLMRREFVKMMERRESIYTIQYNIRSF 823
Query: 3346 QTT-----------IDELREDMETERNARNKAE--MTRREVVAQLEKVKGDVLDKVDEAT 3486
I L + ETE+ E + +E +A+ E K ++ +K
Sbjct: 824 MNVKHWPWMKVYYKIKPLLKSAETEKELATMKEDFVKCKEALAKAEAKKKELEEK----- 878
Query: 3487 MLQDLMSRKDEEVNATKRA--IEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQ 3660
M+ L + D ++ + + + EG I+ K + +++E +++E ++ ++
Sbjct: 879 MVALLQEKNDLQLAVASESENLSDAEERCEGLIKS-KIQLEAKLKETTERLEDEEEINAE 937
Query: 3661 LEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQ 3840
L ++ + + E +++ ++I L+ + A ++K++ E + + +A DE I +
Sbjct: 938 LTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMASQDES----IAK 993
Query: 3841 LERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQL 4020
L + + L +E H Q+ L T+L+ +Q+
Sbjct: 994 LTKEKKAL--------QEAH-----QQTLDDLQAEEDKVNTLTKSKTKLE-------QQV 1033
Query: 4021 EDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAE-----ESVNQQLEELRKKNL 4185
+D + +L EK+ LR LE+ A R+ G+ + E E+ QQ EE KK
Sbjct: 1034 DDLEGSLEQEKK----LRMDLER---AKRKLEGDLKLAQESIMDLENDKQQSEEKIKKKD 1086
Query: 4186 RDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMA 4365
+ L ++E+ + ++ + K++Q +E+ E+E RA+ EK++ ++
Sbjct: 1087 FETAQLLSKIEDEQSLGAQLQKKIKELQARIEELEEEIEAERAARAKVEKQRADLSRELE 1146
Query: 4366 EERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSIS 4545
E +++A A + + RE L +++ E + + +L+++ DS++
Sbjct: 1147 EISERLEEAGGATAAQIEMNKKREAEFQKLRRDLE---ESTLQHEATAAALRKKQADSVA 1203
Query: 4546 NKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDR 4725
+ G+ + L++ K+ LE E ++ ++++++L N++ A+ LE + R
Sbjct: 1204 ---ELGEQIDNLQRVKQKLEKEKSEYKMEIDDLSSNMEAVAKAKANLE--------KMCR 1252
Query: 4726 AISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANR 4905
+ ++ E + K L+QI DL + R +++ + GE +QLE
Sbjct: 1253 TVEDQLSEIKSKNDENLRQINDLS--------------AQRARLQTENGEFGRQLEEKEA 1298
Query: 4906 LKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA----DRKFRAVEAEREQLRE 5073
L + E + + EE +AK +A ++ A D E E+E E
Sbjct: 1299 LVSQLTRGKQAFTQQIEELKRQIEEEVKAKNALAHAVQSARHDCDLLREQFEEEQEAKAE 1358
Query: 5074 ANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAID 5253
G+ +A + + E K++L ++ + S C
Sbjct: 1359 LQRGMSKANSEVAQWRTKYETDAIQRTEELEESKKKLAQRLQEAEEQIEAVNSKCASLEK 1418
Query: 5254 KQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES---GAQSRARA 5424
+++ Q ++E + D+ L + ++++ ++ ++K K E ++ GAQ AR+
Sbjct: 1419 TKQRLQGEVEDLMIDVERANALAANLDKKQRNFDKVLAEWKQKYEEGQAELEGAQKEARS 1478
Query: 5425 QMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEK 5604
L E+ L+ + R + L++ ++D T+Q + ++ + ++ +
Sbjct: 1479 LSTELFKMKNSYEETLD----QLETLKRENKNLQQEISDLTEQLGETGKSIHELEKAKKT 1534
Query: 5605 SNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ ++ L+EAE + E +K VQ E + +
Sbjct: 1535 VETEKAEIQTALEEAEGTLEHEESKILRVQLELNQV 1570
Score = 66.2 bits (160), Expect = 9e-09
Identities = 105/506 (20%), Positives = 209/506 (40%), Gaps = 46/506 (9%)
Frame = +1
Query: 4360 MAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIM----KEHLEESD-------RV 4506
M E+ V ++AL +A +EL ++ +L N++ + E+L +++ +
Sbjct: 854 MKEDFVKCKEALAKAEAKKKELEEKMVALLQEKNDLQLAVASESENLSDAEERCEGLIKS 913
Query: 4507 RRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRL 4686
+ L+ +L+++ +D + EL KR LE E ++++ +++LE L E +
Sbjct: 914 KIQLEAKLKETTERLEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK--- 970
Query: 4687 EVTNQALKSESDRAISNKDVEAE--EKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIE 4860
T +K+ ++ S + A+ ++++ L + + ++L+ E+ + + K+E
Sbjct: 971 HATENKVKNLTEEMASQDESIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKSKTKLE 1030
Query: 4861 NQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFR 5040
Q+ +LE LE +L+ + +AK + L+ A
Sbjct: 1031 QQVDDLEGSLEQEKKLRMDL---------------------ERAKRKLEGDLKLAQESIM 1069
Query: 5041 AVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEK-RRLEAKIAQXXXXX 5217
+E +++Q E + +K + G ++K + L+A+I +
Sbjct: 1070 DLENDKQQSEEKIK-----KKDFETAQLLSKIEDEQSLGAQLQKKIKELQARIEEL---- 1120
Query: 5218 XXXQSNCELAIDKQRKAQVQLEQITTDLSMERT------------------LNQKTEAEK 5343
E I+ +R A+ ++E+ DLS E +N+K EAE
Sbjct: 1121 -------EEEIEAERAARAKVEKQRADLSRELEEISERLEEAGGATAAQIEMNKKREAEF 1173
Query: 5344 QSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRL 5523
Q L R ES Q A A AAL K D + G++ R ++L
Sbjct: 1174 QKLRRDLE---------ESTLQHEATA--AALRKK---QADSVAELGEQIDNLQRVKQKL 1219
Query: 5524 EKRLNDTTQQFED---EKRANEQAKELLEK---------SNLKNRNLR--RQLDEAEDEM 5661
EK ++ + +D A +AK LEK S +K++N RQ+++ +
Sbjct: 1220 EKEKSEYKMEIDDLSSNMEAVAKAKANLEKMCRTVEDQLSEIKSKNDENLRQINDLSAQR 1279
Query: 5662 SRERTKHRNVQREADDLLDANEQLTR 5739
+R +T++ R+ ++ QLTR
Sbjct: 1280 ARLQTENGEFGRQLEEKEALVSQLTR 1305
>gi|11121496|emb|CAC14945.1| dJ756N5.1.1 (Continues in Em:AL133324 as
dJ1161H23.3 ) [Homo sapiens]
Length = 1889
Score = 1102 bits (2850), Expect = 0.0
Identities = 658/1873 (35%), Positives = 1028/1873 (54%), Gaps = 37/1873 (1%)
Frame = +1
Query: 202 DVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIY 381
++Q NPP+FD +EDM+ +T+LNEASVLHNL+ RY +IYTYSGLFCV INPYK LP+Y
Sbjct: 8 ELQPMNPPRFDLLEDMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCVTINPYKWLPVY 67
Query: 382 SEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQY 561
+ ++ +KGK+R + PPHI+A+AD AY ML+ R++QS+L TGESGAGKT NTK+VIQY
Sbjct: 68 TASVVAAYKGKRRSDSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAGKTVNTKRVIQY 127
Query: 562 LAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSS 741
A VA A G LE Q+++ANP +EAFGN+KT++NDNSS
Sbjct: 128 FAIVAALGDGPGKKA----------------GTLEDQIIEANPAMEAFGNAKTLRNDNSS 171
Query: 742 RFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYL 921
RFGKFIRI+F SG ++ A+I+ YLLEKSRV+ Q ERS+H++YQIL G + + L
Sbjct: 172 RFGKFIRIHFGPSGKLASADIDSYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQDMLL 231
Query: 922 LE-GVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNL 1098
L +Y F IT+ N++D +E +T ++M I+GF+ DE + ++V A+L GN+
Sbjct: 232 LSMNPYDYHFCSQGVITVDNMNDGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNM 291
Query: 1099 EFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEF 1278
+F Q+++ +QA K +L+G+ +L K L PR++VG E+V K Q+ EQ F
Sbjct: 292 KFKQKQREEQAEADGTESADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQVVF 351
Query: 1279 AVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYT 1458
AV A+AKA+Y+RLF+WLV+RIN++LD T FIG+LDIAGFEIF+ NSFEQ+CIN+T
Sbjct: 352 AVGALAKATYDRLFRWLVSRINQTLD-TKLPRQFFIGVLDIAGFEIFEFNSFEQLCINFT 410
Query: 1459 NEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFP 1638
NEKLQQ FN MF+LEQEEY+REGI+W FIDFGLDLQP IDLIEKP+G+L++L+EEC+FP
Sbjct: 411 NEKLQQFFNQHMFVLEQEEYKREGIDWVFIDFGLDLQPCIDLIEKPLGILSILEEECMFP 470
Query: 1639 KANDKSFVEKLQKTH-NKHPKFIV--PDMRSK--SHFAVVHYAGRVDYSADQWLMKNMDP 1803
KA+D SF KL H K P F PD + K +HF VVHYAG V YS WL KN DP
Sbjct: 471 KASDASFRAKLYDNHAGKSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNKDP 530
Query: 1804 LNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRK-GMFRTVSQLHKEQL 1980
LNE VV + Q S + +A ++++ +AG C+ E ++ + +K F+TVSQLHKE L
Sbjct: 531 LNETVVPIFQKSQNRLLATLYEN--YAGSCSTEPPKSGVKEKRKKAASFQTVSQLHKENL 588
Query: 1981 TKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPF 2160
KLMT LR T PHFVRCI+PN K G +++ LVL QLRCNGVLEGIRICRQGFPNR+ +
Sbjct: 589 NKLMTNLRATQPHFVRCIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLLY 648
Query: 2161 QEFRHRYEILTPDVIPKN-FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEE 2337
+FR RY IL P IP + F+D +++ K++ +LD+D Y+ G +KVFF+ G+L LEE
Sbjct: 649 TDFRQRYRILNPSAIPDDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVFFKAGLLGVLEE 708
Query: 2338 ERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTK 2517
RD +L ++ QA+ RG L R Y N A+ ++NW W +LF K
Sbjct: 709 LRDQRLAKVLTLLQARSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAVKNWSWMKLFFK 768
Query: 2518 VKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQES 2697
+KPLL+ + ++E+ A ELR + L E +E E+ + E+ + QLQ E
Sbjct: 769 MKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQ 828
Query: 2698 ENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXX 2877
+N A+ ++ L +LE V ++ +RL RRK + +
Sbjct: 829 DNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDID 888
Query: 2878 XXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEE 3057
+K + ++ L E+
Sbjct: 889 DLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEED 948
Query: 3058 RAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEE 3237
R KAK RLE Q+ +LE L +E++ + + E+ KRKL +L+ +++ +A+ ++
Sbjct: 949 RVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQ 1008
Query: 3238 LNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMT 3417
L +L K+D EL R ++E MQK+++++Q +EL E++E ER AR + E
Sbjct: 1009 LEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQ 1068
Query: 3418 RREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAK 3597
R E +LE++ + + + ++ +++ E+ +R +E+ E + + K
Sbjct: 1069 RAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRK 1128
Query: 3598 FSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAH 3777
+ EL +Q++ ++ R +LEK++++ E D+A + L ++A +K + +E
Sbjct: 1129 QAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQ 1188
Query: 3778 LMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXX 3957
L E + + E Q R + E L+R+ EE+E + + R A A
Sbjct: 1189 LSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEEL 1248
Query: 3958 XXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKA 4137
++ K A + + L + + L ++ EE +A L++ + A + R K
Sbjct: 1249 RRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKY 1308
Query: 4138 EESVNQQLEELRKKNLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENV 4308
E Q+ EEL + + LQ+ E E A + + ++K ++Q E ED ++ELE
Sbjct: 1309 EADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERA 1368
Query: 4309 RASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHL 4488
++ +K+Q+ E + E R ++ + +A +E R T + L + + E L
Sbjct: 1369 TSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEAL 1428
Query: 4489 EESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAE 4668
E R ++LQ+E+ D GK++ ELEK K++LE E ++++ +EE E L++ E
Sbjct: 1429 ETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEE 1488
Query: 4669 DARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHR 4848
LR+++ +K+E DR ++ KD E RR + + L+ L+ E R ++ A+ +
Sbjct: 1489 TKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLK 1548
Query: 4849 KKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREAD 5028
KK+E + +LE QL A R E E Q +E ++ ++ + +
Sbjct: 1549 KKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALE 1608
Query: 5029 RKFRAVEAEREQLREANEGLMQARK----QXXXXXXXXXXXRAKGGGISSEEKRRLEAKI 5196
R+ + AE E+LR A E ++R+ + ++ G+ + +K++LEA +
Sbjct: 1609 RRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLN-QKKKLEADL 1667
Query: 5197 AQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYK 5376
AQ A +K +KA + +L E+ + E K++LE++ R+ +
Sbjct: 1668 AQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQ 1727
Query: 5377 AKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQF 5556
A++ E E A + Q+ LEAKV+ LE +L+ E ++ A + R+ E+R+ + Q
Sbjct: 1728 ARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQA 1787
Query: 5557 EDEKRANEQAKELLEKSNLKNRNLRRQLDEA----------------------EDEMSRE 5670
E++++ + ++L++K K ++ +RQ +EA E + +
Sbjct: 1788 EEDRKNLARMQDLVDKLQSKVKSYKRQFEEAVSALGPGHLDRAPQLCPRVCGQEQQANTN 1847
Query: 5671 RTKHRNVQREADD 5709
K+R Q E DD
Sbjct: 1848 LAKYRKAQHELDD 1860
Score = 103 bits (256), Expect = 7e-20
Identities = 158/731 (21%), Positives = 299/731 (40%), Gaps = 40/731 (5%)
Frame = +1
Query: 3679 QADQERADMAQEIALLQASRADIDKKRK-IHEAHL----------MEIQA---NLAESDE 3816
QA++E A + E+ L+ + A + KR+ + E H+ +++QA NLA+++E
Sbjct: 777 QAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEE 836
Query: 3817 HKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIA 3996
LI + ++ L+ E+EE A++ R
Sbjct: 837 RCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAAR------------------------ 872
Query: 3997 NINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAAR---QGAGEARRKAEESVNQQLEE 4167
R+LEDE L + ++ + A EKE A + E +ESV + +E
Sbjct: 873 ----RRKLEDECTELKKDIDDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKE 928
Query: 4168 LRKKNLRDVEHLQKQLEESEVAKERI---LQSKKKIQQELEDSSMELENVRASHRDSEKR 4338
KK L++ Q+ L + + ++R+ ++K +++Q++ED LE + D+E+
Sbjct: 929 --KKALQEAH--QQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERA 984
Query: 4339 QKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSL 4518
++K E + + +V A D+ + ++L+ +++ E+ + +E+ + +
Sbjct: 985 KRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDS-------ELSQLSLRVEDEQLLGAQM 1037
Query: 4519 QQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTN 4698
Q K + EL+ LE EL R +E Q AE AR E++
Sbjct: 1038 Q--------------KKIKELQARAEELEEELEAERAARARVEK--QRAEAARELEELSE 1081
Query: 4699 QALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGEL 4878
+ ++ A + E G L+ R+LE E R ++ + R+K EL
Sbjct: 1082 RLEEAGGASAGQREGCRKREAELGRLR--RELE---EAALRHEATVAALRRKQAEGAAEL 1136
Query: 4879 EQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAER 5058
+Q++ R++++ E ++E ++ E + A++ R E
Sbjct: 1137 GEQVDSLQRVRQKLEKEKS-------ELRMEVDDLAANVETLTRAKASAEKLCRTYE--- 1186
Query: 5059 EQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISS--EEKRRLEAKIAQXXXXXXXXQS 5232
+QL EA + + ++Q + + G +S EEK L +++++
Sbjct: 1187 DQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLE 1246
Query: 5233 NCELAIDKQRKAQVQLEQITTDLSMERTL---NQKTEAEKQS-LERSNRDYKAKITELES 5400
++++ KA+ L L + L + EAE Q+ L+R A++ + S
Sbjct: 1247 ELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRS 1306
Query: 5401 GAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANE 5580
++ A + LE + L +L + AAN LEK + ED E
Sbjct: 1307 KYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELE 1366
Query: 5581 QAKELLEKSNLKNRNLRRQLDE---AEDEMSRE-----------RTKHRNVQREADDLLD 5718
+A + K R+L R L+E E+EM RE T+ ++ ++ L+
Sbjct: 1367 RATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALE 1426
Query: 5719 ANEQLTRELMN 5751
A E L RE N
Sbjct: 1427 ALETLKRENKN 1437
>gi|39584408|emb|CAE72546.1| Hypothetical protein CBG19730
[Caenorhabditis briggsae]
Length = 1963
Score = 1097 bits (2838), Expect = 0.0
Identities = 650/1936 (33%), Positives = 1055/1936 (53%), Gaps = 25/1936 (1%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
QYL+ R + + + + +K CW+PD EG+L G I D+V + + +VT+
Sbjct: 10 QYLRRSREQILEDQS-KPYDSKKNCWIPDPEEGYLAGEITATKGDQVTI-VTARGNEVTL 67
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++ VQ+ NPPKF+K EDMS LT+LN+ASVLHNL+ RY + LIYTYSGLFCVVINPYK+L
Sbjct: 68 KKELVQEMNPPKFEKTEDMSNLTFLNDASVLHNLRSRYAAMLIYTYSGLFCVVINPYKRL 127
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIY++ + F GK++ EMPPH+FA++D AYR+MLQ+ E+QS+L TGESGAGKTENTKKV
Sbjct: 128 PIYTDSVARMFMGKRKTEMPPHLFAVSDEAYRNMLQDHENQSMLITGESGAGKTENTKKV 187
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
I Y A V + + +A + V LE Q++Q NP+LEAFGN+KTV+N+
Sbjct: 188 IAYFASVGASQQEGGADADPSKKKVT----------LEDQIVQTNPVLEAFGNAKTVRNN 237
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRI+F G ++ +IE YLLEKSRV+RQA ER +HIFYQI + K
Sbjct: 238 NSSRFGKFIRIHFSKHGRLASCDIEHYLLEKSRVIRQAPGERCYHIFYQIYSDFRPELKK 297
Query: 913 EYLLE-GVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLL 1089
E LL+ + +Y F+ +T+ ++DV+EF T + I+ F+ E R++SA++ +
Sbjct: 298 ELLLDLPIKDYWFVAQAELTIDGINDVEEFQLTDEAFDILNFSATEKQDCYRLMSALMHM 357
Query: 1090 GNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQ 1269
GN++F Q + +QA +K + G+ + KA +PR+KVG E+V+K QN EQ
Sbjct: 358 GNMKFKQRPREEQAEPDGTDEAEKASAMYGVSAEDFLKALTKPRVKVGTEWVSKGQNCEQ 417
Query: 1270 AEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICI 1449
+AV A+AK Y R+F WLV + N +LD+ FIG+LDIAGFEIFD NSFEQ+ I
Sbjct: 418 VTWAVGAMAKGLYSRVFNWLVKKCNLTLDQKGIDRDFFIGVLDIAGFEIFDFNSFEQLWI 477
Query: 1450 NYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEEC 1629
N+ NEKLQQ FN+ MF+LEQEEY REGI+W FIDFGLDLQ I+LIEKP+G++++LDEEC
Sbjct: 478 NFVNEKLQQFFNHHMFVLEQEEYAREGIQWTFIDFGLDLQACIELIEKPLGIISMLDEEC 537
Query: 1630 LFPKANDKSFVEKLQKTH-NKHPKFIVP----DMRSKSHFAVVHYAGRVDYSADQWLMKN 1794
+ PKA D + KL H KHP F P + ++HFA+ HYAG V Y+ WL KN
Sbjct: 538 IVPKATDLTLASKLVDQHLGKHPNFEKPKPPKGKQGEAHFAMRHYAGTVRYNCLNWLEKN 597
Query: 1795 MDPLNENVVGLMQNS-TDPFVAGIWKDAEFAGICAAEMNETAFG--MRSRKGMFRTVSQL 1965
DPLN+ VV M+ S + + IW+D AA+ E G + + G F TVS L
Sbjct: 598 KDPLNDTVVSCMKASKQNDLLVEIWQDYTTQEEAAAKAKEGGGGGKKKGKSGSFMTVSML 657
Query: 1966 HKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFP 2145
++E L LMT L T PHF+RCIIPN +K+SG I++ LVL QL CNGVLEGIRICR+GFP
Sbjct: 658 YRESLNNLMTMLNKTHPHFIRCIIPNEKKQSGMIDAALVLNQLTCNGVLEGIRICRKGFP 717
Query: 2146 NRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITAL----DIDTNLYRIGQSKVFFRT 2313
NR +F RY IL K+ D K+ +++ L ++ ++RIG +KVFF+
Sbjct: 718 NRTLHPDFVQRYAILAAKE-AKSDDDKKKCAEAIMSKLVNDGSLNEEMFRIGLTKVFFKA 776
Query: 2314 GVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNW 2493
GVLAHLE+ RD KL ++ FQAQ R L + N ++ LR W
Sbjct: 777 GVLAHLEDIRDEKLAIILTGFQAQIRWHLGLKERKRRMEQRAGLLIVQRNVRSWCTLRTW 836
Query: 2494 QWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVI 2673
+W++L+ KVKP+L+ + +E+ +D+++A +E L K E +E E+ +++ E+ +
Sbjct: 837 EWFKLYGKVKPMLKAGKEAEELEKINDKVKALEESLAKEEKLRKELEESSAKLVEEKTSL 896
Query: 2674 QEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETV 2853
L+ ++ ++ +L+ + ++ + ++ D+L+ ++K V
Sbjct: 897 FTNLESTKTQLSDAEERLAKLEAQQKDATKQLAELNDQLADNEDRTADVQRAKKKVEAEV 956
Query: 2854 RDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLT 3033
+K + D +A L
Sbjct: 957 EALKKQIQDLEMSLRKAESEKQSKDHQIRSLQDEMQQQDEAIAKLNKEKKHQEEINRKLM 1016
Query: 3034 TQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLA 3213
L E++ H K K +LE L +LE L RE++ +++L++ KRK+ EL+ +++++
Sbjct: 1017 EDLQSEEDKGNHQNKIKAKLEQTLDDLEDSLEREKRARADLDKQKRKVEGELKIAQENID 1076
Query: 3214 EKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERN 3393
E + +L N L K++ EL +R ++E A V+ +Q+Q++D Q+ I EL E++E ER
Sbjct: 1077 ESGRQRHDLENNLKKKESELHSVSSRLEDEQALVSKLQRQIKDGQSRISELEEELENERQ 1136
Query: 3394 ARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTME 3570
+R+KA+ + ++ +LE++ G+ LD+ AT Q ++ +++ E+ +R +E+ E
Sbjct: 1137 SRSKADRAKSDLQRELEEL-GEKLDEQGGATAAQVEVNKKREAELAKLRRDLEEANMNHE 1195
Query: 3571 GKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADID 3750
++ + K + V EL DQ++Q K ++++EK + QA ++ D+A ++ +++ + +
Sbjct: 1196 NQLAGLRKKHTDAVAELTDQLDQLNKAKAKVEKDKAQAVRDAEDLAAQLDQETSAKLNNE 1255
Query: 3751 KKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLA 3930
K K E L E+Q+ E + R E L R E+ E + R +
Sbjct: 1256 KLAKQFELQLTELQSKADEQSRQLQDFTSLKGRLHSENGDLVRQLEDAESQVNQLTRLKS 1315
Query: 3931 TAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHA-- 4101
R + +A+ + E L + +EE EG L + A
Sbjct: 1316 QLTSQLEEARRTADEEARERQTVAAQAKNYQHEAEQLQESLEEEIEGKNEILRQLSKANA 1375
Query: 4102 -----ARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKI 4266
+ GE KA+E LE+ +++ + + LQ+ L+ + + ++K ++
Sbjct: 1376 DIQQWKARFEGEGLLKADE-----LEDAKRRQAQKINELQEALDAANSKIASLEKTKSRL 1430
Query: 4267 QQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRV 4446
+L+D+ +++E EK+QK F+ + E R + D ++LR+ T +
Sbjct: 1431 VGDLDDAQVDVERANGVASALEKKQKGFDKIIDEWRKKTDDLAAELDGAQRDLRNTSTDL 1490
Query: 4447 LSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMR 4626
N + + E +E R +SL QE++D + G++VHE++K R LE E +++
Sbjct: 1491 FKAKNAQEELAEVVEGLRRENKSLSQEIKDLTDQLGEGGRSVHEMQKIIRRLEIEKEELQ 1550
Query: 4627 VQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENEL 4806
++E E L+ E LR +V ++SE ++ I K+ E E R+ + + ++ L
Sbjct: 1551 HALDEAEAALEAEESKVLRAQVEVSQIRSEIEKRIQEKEEEFENTRKNHARALESMQASL 1610
Query: 4807 ENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEAR 4986
E E +GK+ + +KK+E I ELE L+ AN+ + E Q++ EE +
Sbjct: 1611 ETEAKGKAELLRVKKKLEADINELEIALDHANKANADAQKNLKRYQEQVRELQLQVEEEQ 1670
Query: 4987 QAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGG-IS 5163
+ D A+++ +++E+E+L ANE +ARKQ + +S
Sbjct: 1671 RNGADTREQFFNAEKRATLLQSEKEELLVANEAAERARKQAEYEAADARDQANEANAQVS 1730
Query: 5164 S--EEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEA 5337
S KR+LE +I + + A ++ +KA ++ +L E+ +Q +
Sbjct: 1731 SLTSAKRKLEGEIQAIHADLDETLNEYKAAEERSKKAVADATRLAEELRQEQEHSQHVDR 1790
Query: 5338 EKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAAR 5517
++ LE+ ++ + ++ E E+ A + +A LE +V+ LE +L+ E + AN+
Sbjct: 1791 LRKGLEQQLKEIQVRLDEAEAAALKGGKKVIAKLEQRVRELESELDGEQRRFQDANKNLG 1850
Query: 5518 RLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQR 5697
R ++R+ + Q +++K+ E+ ++L++K K + ++Q++EAE+ + K++ +
Sbjct: 1851 RADRRVRELQFQVDEDKKNFERLQDLIDKLQQKLKTQKKQVEEAEELANLNLQKYKQLTH 1910
Query: 5698 EADDLLDANEQLTREL 5745
+ +D + +Q L
Sbjct: 1911 QLEDAEERADQAENSL 1926
Score = 70.1 bits (170), Expect = 6e-10
Identities = 96/479 (20%), Positives = 191/479 (39%), Gaps = 65/479 (13%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLM 3255
KAK E +L E+ + L RE + S+ E++D D L E V E+ +
Sbjct: 1492 KAKNAQE-ELAEVVEGLRRENKSLSQ----------EIKDLTDQLGEGGRSVHEMQKIIR 1540
Query: 3256 KRD---EELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETE-RNARNKAEMTRR 3423
+ + EELQH L DE A + + ++ Q + ++R ++E + + E TR+
Sbjct: 1541 RLEIEKEELQHAL---DEAEAALEAEESKVLRAQVEVSQIRSEIEKRIQEKEEEFENTRK 1597
Query: 3424 EVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQK--AK 3597
LE ++ + + L + + + ++N + A++ H + + QK +
Sbjct: 1598 NHARALESMQASLETEAKGKAELLRVKKKLEADINELEIALD---HANKANADAQKNLKR 1654
Query: 3598 FSRQVEELHDQIEQHKKQ----RSQL------------------------EKQQNQADQE 3693
+ QV EL Q+E+ ++ R Q E+ + QA+ E
Sbjct: 1655 YQEQVRELQLQVEEEQRNGADTREQFFNAEKRATLLQSEKEELLVANEAAERARKQAEYE 1714
Query: 3694 RADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAES-DEHKRT-------------L 3831
AD + A + + ++ E + I A+L E+ +E+K L
Sbjct: 1715 AADARDQANEANAQVSSLTSAKRKLEGEIQAIHADLDETLNEYKAAEERSKKAVADATRL 1774
Query: 3832 IDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANIN-R 4008
++L + ++ H++R+R+ E +Q RL A + IA + R
Sbjct: 1775 AEELRQEQEHSQHVDRLRKGLEQQLKEIQVRLDEAEAAALKGG-------KKVIAKLEQR 1827
Query: 4009 ARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARR----------------KAE 4140
R+LE E + ++A ++ + + E ++ K +
Sbjct: 1828 VRELESELDGEQRRFQDANKNLGRADRRVRELQFQVDEDKKNFERLQDLIDKLQQKLKTQ 1887
Query: 4141 ESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRAS 4317
+ ++ EEL NL+ + L QLE++E ++ S K++ + S+ +++S
Sbjct: 1888 KKQVEEAEELANLNLQKYKQLTHQLEDAEERADQAENSLSKMRSKSRASASVAPGLQSS 1946
>gi|39592202|emb|CAE75423.1| Hypothetical protein CBG23416
[Caenorhabditis briggsae]
Length = 1969
Score = 1096 bits (2835), Expect = 0.0
Identities = 645/1939 (33%), Positives = 1057/1939 (54%), Gaps = 27/1939 (1%)
Frame = +1
Query: 16 YLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTIS 195
+L + R A A A + +K CW+PD +GF+ I+ T D+V V V Q+T+
Sbjct: 16 FLGMSREAKAASAA-RPFDSKKNCWIPDPEDGFVAAEIQSTTGDQVTVVTVK-GNQITVK 73
Query: 196 RDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLP 375
+D Q+ NPPKFDK EDM+ LT+LNEASVL NLKDRY +IYTYSGLFCVVINPYK+LP
Sbjct: 74 KDQCQEMNPPKFDKTEDMANLTFLNEASVLGNLKDRYKDLMIYTYSGLFCVVINPYKRLP 133
Query: 376 IYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVI 555
IYSE +I+ F GK+R+EMPPH+FA++D AYR+M+Q++E+QS+L TGESGAGKTENTKKVI
Sbjct: 134 IYSESVIKHFMGKRRNEMPPHLFAVSDEAYRNMVQDKENQSMLITGESGAGKTENTKKVI 193
Query: 556 QYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDN 735
Y A + GAT+ AAA K + G LE Q++Q NP+LEAFGN+KTV+N+N
Sbjct: 194 SYFA-IVGATQ-----AAAGG----KKEEGKKGGTLEEQIVQTNPVLEAFGNAKTVRNNN 243
Query: 736 SSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSE 915
SSRFGKFIR +F SG ++G +IE YLLEKSRV+RQA ER +HIFYQI+ G A + +
Sbjct: 244 SSRFGKFIRTHFSGSGKLAGGDIEHYLLEKSRVVRQAPGERCYHIFYQIMSGNDASLRGK 303
Query: 916 YLLEG-VDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 1092
L + Y F +T+ +DD +E T + IMGF D E + R + ++ +G
Sbjct: 304 LKLNNDITYYHFCSQAELTIEGMDDKEEMRLTQEAFDIMGFEDQETMDLYRSTAGIMHMG 363
Query: 1093 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA 1272
++F Q + +QA + +LG+ E KA +PR++VG E+VNK QN EQ
Sbjct: 364 EMKFKQRPREEQAEPDGEEDALNAAAMLGINAEEFLKALTKPRVRVGTEWVNKGQNLEQV 423
Query: 1273 EFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICIN 1452
+AV +AKA Y R+FKW++ R NK+LD + FIG+LDIAGFEIFD+NSFEQ+ IN
Sbjct: 424 SWAVSGLAKAIYARMFKWIINRCNKTLDAKEIERKHFIGVLDIAGFEIFDLNSFEQLWIN 483
Query: 1453 YTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECL 1632
+ NE+LQQ FN+ MF+LEQEEY+REGI W FIDFGLDLQ I+LIEKP+G++++LDEEC+
Sbjct: 484 FVNERLQQFFNHHMFVLEQEEYKREGIAWTFIDFGLDLQACIELIEKPLGIISILDEECI 543
Query: 1633 FPKANDKSFVEKLQKTH-NKHPKFIVP----DMRSKSHFAVVHYAGRVDYSADQWLMKNM 1797
PKA D ++ +KL H KHP F P + +HFA+VHYAG V Y+A+ +L KN
Sbjct: 544 VPKATDMTYAQKLLDQHLGKHPNFQKPKPPKGKQGDAHFAIVHYAGTVRYNANNFLEKNK 603
Query: 1798 DPLNENVVGLMQNSTD-PFVAGIWKD--AEFAGICAAEMNETAFGMRSRKGMFRTVSQLH 1968
DPLN+ V L+++S D + IW+D + AA+ ++ G R + F TVS ++
Sbjct: 604 DPLNDTAVALLKHSVDNNLMLDIWQDYQTQEEAAEAAKAGQSGGGKRGKSSSFATVSMIY 663
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
+E L LM L T PHF+RCIIPN +K SG I+S LVL QL CNGVLEGIRICR+GFPN
Sbjct: 664 RESLNNLMNMLYQTHPHFIRCIIPNEKKASGVIDSALVLNQLTCNGVLEGIRICRKGFPN 723
Query: 2149 RVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNL----YRIGQSKVFFRTG 2316
R+ + +F+HRY IL D + D K++ ++ + D NL ++IG++K+FF+ G
Sbjct: 724 RMLYPDFKHRYAILAADAAKDS--DPKKASVGILDKIANDGNLTDEEFKIGETKIFFKAG 781
Query: 2317 VLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQ 2496
VLA LE+ RD L+ ++ FQ++ R +L++ N A+ LR W+
Sbjct: 782 VLAKLEDLRDEILSRIVTMFQSRIRSYLAKAEVRRRYEQQTGLLIVQRNVRAWCTLRTWE 841
Query: 2497 WWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQ 2676
W++LF KVKP+L+ + + + ++++ +E + + E + E ++ ++ E+ +
Sbjct: 842 WFKLFGKVKPMLKAGKEQEAMGELAEKIQKLEEAVQRGEIARSQLETQVADLVEEKNALF 901
Query: 2677 EQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVR 2856
L+ E N A+ ++ +L LE + D+ +L ++K + +
Sbjct: 902 LSLETEKANLADAEERNEKLNQLKATLESKLTDITGQLEDMQERHEDLTRQKKKTEQELS 961
Query: 2857 DXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTT 3036
D +K + D ++ L
Sbjct: 962 DTKKHVQDLELTLRKAEQEKQSRDHQIRSLQDEMANQDESVAKLNKEKKHQEESNRKLNE 1021
Query: 3037 QLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAE 3216
L E++ H K + +LE Q+ ELE+ ++RE++ +S++E+ KRK+ +L+ +++++ E
Sbjct: 1022 DLQSEEDKVNHLEKIRNKLEQQMDELEETIDREKRSRSDIEKSKRKVEGDLKVAQENIDE 1081
Query: 3217 KMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNA 3396
+ +++ N L +++++L H T+ EE A +Q+Q++++Q I EL E++E+ERN+
Sbjct: 1082 ITKQKQDVENTLKRKEDDLHHASTKLAEEQALAAKLQRQIKELQARIAELEEELESERNS 1141
Query: 3397 RNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK 3576
R KA+ TR E+ +LE++ + + + + +++ E+ +R E+ E
Sbjct: 1142 RQKADRTRNELQRELEEISERLEQQGGFSAAQLEANKKREAEIAKLRREKEEDALNHETA 1201
Query: 3577 IEEQKAKFSRQVEELHDQIE--QHKKQRSQLEKQQNQADQERADMAQEIALLQASRADID 3750
+ + + V EL +Q+E Q K + E+ + Q D E A A + + +R +++
Sbjct: 1202 VSSLRKRQVDAVAELTEQLETLQKLKAKGDAERAKLQRDLEEAQHATDSEV--RARQEVE 1259
Query: 3751 KKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLA 3930
K K E E+Q E + R +E LNR EE ++ ++ R +
Sbjct: 1260 KSYKTIEVQFSELQTKADEQSRQLQDFAALKNRLNNENGDLNRTLEEMDNQVNSLHRLKS 1319
Query: 3931 TAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQ 4110
T +R + A A+ LE E L + +E +A L ++I
Sbjct: 1320 TLQSQLDETRRNFEEESRERQALAATAKNLEHENEILREHLDEEAESKADLTRQISKLNA 1379
Query: 4111 GAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKK---KIQQELE 4281
+ + + + +LEE+ +Q+ + +E +I +K K+ Q+L+
Sbjct: 1380 EIQQWKARFDSEGLNKLEEIEAAKKALQLKVQELSDTNEGLFAKIASQEKVRHKLMQDLD 1439
Query: 4282 DSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLN 4461
D+ ++E A EK +++FE + E + + DA ++ R T +
Sbjct: 1440 DAQSDVEKAAAQVAYYEKHRRQFEKIVEEWKKKTDDLASELDAAQRDNRQLSTDLFKAKT 1499
Query: 4462 EVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE 4641
D + E+L+ + R +SL QE++D + G++V EL+K R LE E +++ ++E
Sbjct: 1500 ANDELAEYLDSTRRENKSLAQEVKDLTDQLGEGGRSVAELQKIVRRLEVEKEELQKALDE 1559
Query: 4642 LEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKR 4821
E L+ E LR ++ ++SE ++ I K+ E E RR + + ++ LE E +
Sbjct: 1560 AEAALEAEEAKVLRAQIEVSQIRSEIEKRIQEKEEEFENTRRNHQRALESMQATLEAETK 1619
Query: 4822 GKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKED 5001
K A+ +KK+E+ I +LE L+ ANR + E Q++ EE ++ K++
Sbjct: 1620 QKEEALRIKKKLESDINDLEIALDHANRANADAQKTIKKYMETVRELQVQIEEEQRQKDE 1679
Query: 5002 IAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEE--- 5172
+ ++++ ++AE+++L + E +AR+ R + +S++
Sbjct: 1680 LREQFLASEKRNGILQAEKDELAQQAEAAERARRN---AEADCIELREQNNDLSNQVSSL 1736
Query: 5173 ---KRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEK 5343
+R+LE ++ + + A ++ +KA ++ +L E+ + E +
Sbjct: 1737 TGWRRKLEGELLAVHAELEELVTELKNAQEQGQKASADAARLAEELRQEQEHSMHIERIR 1796
Query: 5344 QSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRL 5523
+ LE ++ + ++ + E+ A + +A LEA+++ +E +L+ E + + R+
Sbjct: 1797 KGLELQIKEMQIRLDDAENAALKGGKKIIAQLEARIRAIEQELDGEQRRHQDTEKNWRKA 1856
Query: 5524 EKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQ--- 5694
E+R+ + Q +EK+ E+ EL++K K + +RQ++EAE+ + K++ +Q
Sbjct: 1857 ERRVKEVEFQVIEEKKNEERLTELVDKLQTKLKIFKRQVEEAEEVAASNLNKYKVLQAQF 1916
Query: 5695 READDLLDANEQLTRELMN 5751
+AD+ + E ++ N
Sbjct: 1917 EQADERAEIAENALSKMRN 1935
>gi|47208995|emb|CAF91401.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 2819
Score = 1096 bits (2834), Expect = 0.0
Identities = 658/1968 (33%), Positives = 1068/1968 (53%), Gaps = 90/1968 (4%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K C+VPD ++ S+ D+V V ++ + VT+ DV NPPKFDKIEDM+
Sbjct: 34 KKECFVPDPEIEYVKASVTSRDGDKVTVN-TESGKTVTVKECDVHPQNPPKFDKIEDMAM 92
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
T+L+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+++++ ++GKKR E PP
Sbjct: 93 FTFLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNQEVVVAYRGKKRTEAPP 152
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIF+I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A K +A +
Sbjct: 153 HIFSISDNAYQYMLADRENQSILITGESGAGKTVNTKRVIQYFASIAAVPSGKKDTSAEK 212
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
+ G LE Q++QANP LEAFGN+KT++NDNSSRFGKFIRI+FD G ++
Sbjct: 213 K------------GTLEDQIIQANPALEAFGNAKTIRNDNSSRFGKFIRIHFDNRGKLAS 260
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLL--EGVDNYRFLVNRGIT 969
A+IE YLLEKSRV Q + ER +HIFYQIL E E LL +Y F+ T
Sbjct: 261 ADIETYLLEKSRVTYQLKAERDYHIFYQILSQVK-PEILEMLLITNNPYDYAFISQGETT 319
Query: 970 LPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDR 1149
+ +++D E +T + ++GF +E +S+ ++ A++ GN++F Q+++ +QA
Sbjct: 320 VASINDADELVATDEAFDVLGFTQEEKNSVYKLTGAIMHYGNMKFKQKQREEQAEADGTE 379
Query: 1150 VIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWL 1329
K +L+GL +L K PR+KVG E+V K QN Q +A+ A++K+ YE++F W+
Sbjct: 380 DADKAAYLMGLNSADLIKGLCHPRVKVGNEWVTKGQNVAQVYYAIGALSKSVYEKMFLWM 439
Query: 1330 VTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQ 1509
V RIN+SLD T + FIG+LDIAGFEIFD N+FEQ+CIN+TNEKLQQ FN+ MF+LEQ
Sbjct: 440 VVRINQSLD-TKQPRQYFIGVLDIAGFEIFDFNTFEQMCINFTNEKLQQFFNHHMFVLEQ 498
Query: 1510 EEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-N 1686
EEY++EGIEW+FIDFG+DLQ IDLIEKPMG++++L+EEC+FPKA+D +F KL H
Sbjct: 499 EEYKKEGIEWEFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKASDATFKAKLYDNHLG 558
Query: 1687 KHPKFIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVA 1857
K F P + + ++HFA++HYAG VDY+ + WL+KN DPLNE VVGL Q S ++
Sbjct: 559 KSANFQKPRIVKGKPEAHFALMHYAGTVDYNINNWLVKNKDPLNETVVGLYQKSNLKLLS 618
Query: 1858 GIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCII 2037
++ A +AG ++ G + + F+TVS LH+E L KLMT LR+T PHFVRCII
Sbjct: 619 ILF--ANYAG-ADSDTGGKGKGSKKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCII 675
Query: 2038 PNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-N 2214
PN K G + LV+ QLRCNGVLEGIRICR+GFPNR+ + +F+ RY IL P+ +P+
Sbjct: 676 PNETKTPGAMEHPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRILNPNAVPEGQ 735
Query: 2215 FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRG 2394
FID K++ K++ +LDID N Y++G +KVFF+ G+L LEE RD +L +I QA+ RG
Sbjct: 736 FIDNKKAAEKLLGSLDIDHNQYKLGHTKVFFKAGLLGLLEEMRDDRLALIITGIQARSRG 795
Query: 2395 FLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDD 2574
L+R + N A++ ++NW W +L+ K+KPLL+ + E+ +
Sbjct: 796 LLARIEFQKIVERRDALLVIQWNVRAFMGVKNWPWMKLYFKIKPLLRSAEAEKEMANMKE 855
Query: 2575 ELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQE 2754
E KE K E +E E+K ++ E+ +Q Q+Q E +N + ++ L +
Sbjct: 856 EFLKLKEAYAKSEARRKELEEKTVTLLQEKNDLQLQVQSEQDNLCDAEERCEGLIKSKIQ 915
Query: 2755 LEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQX 2934
LE + ++ +RL +RK + + +K +
Sbjct: 916 LEAKIKELTERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 975
Query: 2935 XXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLH-- 3108
+ L E++ KAK +LE Q+
Sbjct: 976 VKNLTEEMAALDEIIAKLTKEKKALQEAHQQTLDDLQSEEDKVNTLTKAKTKLEQQVDDV 1035
Query: 3109 ---------------------ELEQDLNRERQYKSELEQHKRKL----------LAELED 3195
+LE L +E++ + +LE+ KRKL L +LE+
Sbjct: 1036 SITFKNDATKIGIAVIWNFVPQLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESLMDLEN 1095
Query: 3196 SKDHLAEKMGKV--EELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQ------- 3348
K L EK+ K+ ++ ++MK D E+ H ++ ++E A +QK+++++Q
Sbjct: 1096 DKQQLEEKLKKLRKKKTRREVMK-DFEISHLNSKIEDEQAMSAQLQKKLKELQVRCAHDN 1154
Query: 3349 -----------------------TTIDELREDMETERNARNKAEMTRREVVAQLEKVKGD 3459
I+EL E++E ER AR K E R ++ +LE++ +
Sbjct: 1155 RLFSQVTIMSPKKKKKKSLLSLKARIEELEEELEAERAARAKVEKQRADLARELEEI-SE 1213
Query: 3460 VLDKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIE 3636
L++ AT Q M++K E E +R +E+ E + K + V +L +QI+
Sbjct: 1214 RLEEAGGATTAQIEMNKKREAEFLKLRRDLEEATLQHEATAAALRKKQADSVADLGEQID 1273
Query: 3637 QHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDE 3816
++ + +LEK++++ E D+ + + S+A+++K + E + E + +S+E
Sbjct: 1274 NLQRVKQKLEKEKSELRLELDDVVSNMEQVVKSKANLEKMCRSLEDQMQEYK---TKSEE 1330
Query: 3817 HKRTLID---QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL 3987
+RT+ D Q + + E L+R EE++ + + R + +
Sbjct: 1331 GQRTINDVTIQKAKLQTENGELSRQLEEKDSLVSQLTRGKQSYTQQMEDLKRQLEEEIKA 1390
Query: 3988 KIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEE 4167
K A + + + + L ++ EE + +A L++ + A + R K E Q+ EE
Sbjct: 1391 KNALAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEE 1450
Query: 4168 LRKKNLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKR 4338
L + + + LQ+ E E + + ++K ++Q E+ED +++E A+ +K+
Sbjct: 1451 LEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKK 1510
Query: 4339 QKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSL 4518
Q+ F+ +AE + +++ + + +E R T + L N + E+LE R ++L
Sbjct: 1511 QRNFDKILAEWKQKYEESQSELEGSQKEARSLSTELFKLKNSFEESLENLETMKRENKNL 1570
Query: 4519 QQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTN 4698
Q+EL D + K++HELEK ++ LE E ++++ +EE E +L+ E LR+++
Sbjct: 1571 QEELSDLAEQIVEGTKSIHELEKIRKQLEQEKSELQTSLEEAEASLEHEEGKILRIQLEF 1630
Query: 4699 QALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGEL 4878
+K+E +R + KD E E+ +R + + L++ LE E R ++ A+ +KK+E + E+
Sbjct: 1631 NQIKAEIERKLGEKDEEMEQAKRNQQRIVDSLQSSLEAETRSRNEALRLKKKMEGDLNEM 1690
Query: 4879 EQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAER 5058
E QL ANR E + Q++ +E+ +A +D+ + +R+ ++AE
Sbjct: 1691 EIQLSQANRQAAEAQKQLKSVHAHLKDSQLQLDESLRANDDMKENIAIVERRNNLLQAEV 1750
Query: 5059 EQLREANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQ 5229
E+LR + E ++RK Q K++LEA +Q
Sbjct: 1751 EELRASLEQTERSRKLAEQELLDVSERVQLLHSQNTSLLNHKKKLEADASQLQTEVEEAV 1810
Query: 5230 SNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQ 5409
C A +K +KA + +L E+ + E K+++E++ +D + ++ E E A
Sbjct: 1811 QECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIAM 1870
Query: 5410 SRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTT--------QQFEDE 5565
+ Q+ LEA+++ LE +L E ++ + + R+ E+R+ + T Q E++
Sbjct: 1871 KGGKKQVQKLEARIKELESELEAEQRKSCDSVKGIRKYERRIKELTYQASFPHCQPTEED 1930
Query: 5566 KRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
++ + ++L +K LK ++ ++ +EAE++ + TK R +Q E D+
Sbjct: 1931 RKNLSRLQDLADKLQLKVKSYKKATEEAEEQANNNLTKFRKIQHELDE 1978
Score = 219 bits (558), Expect = 6e-55
Identities = 216/1039 (20%), Positives = 449/1039 (42%), Gaps = 48/1039 (4%)
Frame = +1
Query: 2581 RATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRL----QTRN 2748
R+ ++++ + + E ++ ++ V +++A +Q + + S E D + +L Q+
Sbjct: 1315 RSLEDQMQEYKTKSEEGQRTINDVTIQKAKLQTENGELSRQLEEKDSLVSQLTRGKQSYT 1374
Query: 2749 QELEYIVNDMRDRLSXXXXXXXXXXXXR------RKQMETVRDXXXXXXXXXXXXXXXXX 2910
Q++E + + + + R R+Q E ++
Sbjct: 1375 QQMEDLKRQLEEEIKAKNALAHALQSARHDCDLLREQYEEEQEA---------------- 1418
Query: 2911 DKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV----- 3075
K + + + Y+ Q L E A V
Sbjct: 1419 -KAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCS 1477
Query: 3076 ---KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNN 3246
K K RL+N++ +L D+ R + L++ +R L + K E ++E
Sbjct: 1478 SLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELEGSQK 1537
Query: 3247 QLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRRE 3426
+ EL ++E N+ M+++ +++Q + +L E + + ++ E R+
Sbjct: 1538 EARSLSTELFKLKNSFEESLENLETMKRENKNLQEELSDLAEQIVEGTKSIHELEKIRK- 1596
Query: 3427 VVAQLEKVKGDVLDKVDEATML----QDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKA 3594
QLE+ K ++ ++EA + + R E N K IE+ + ++E+ K
Sbjct: 1597 ---QLEQEKSELQTSLEEAEASLEHEEGKILRIQLEFNQIKAEIERKLGEKDEEMEQAKR 1653
Query: 3595 KFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASR--ADIDKKRKIH 3768
R V+ L +E + R++ + + + + + +M EI L QA+R A+ K+ K
Sbjct: 1654 NQQRIVDSLQSSLEAETRSRNEALRLKKKMEGDLNEM--EIQLSQANRQAAEAQKQLKSV 1711
Query: 3769 EAHLMEIQANLAES--------------DEHKRTLIDQLERSRDELDHLNRVREEEEHAF 3906
AHL + Q L ES + L ++E R L+ R R+ E
Sbjct: 1712 HAHLKDSQLQLDESLRANDDMKENIAIVERRNNLLQAEVEELRASLEQTERSRKLAEQEL 1771
Query: 3907 ANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEA-EGLRAHL 4083
++ R+ +N ++LE + + L E EEA + R
Sbjct: 1772 LDVSERVQLLHSQNTSL--------------LNHKKKLEADASQLQTEVEEAVQECRNAE 1817
Query: 4084 EKEIHAARQGAGEARR-KAEESVNQQLEELRKKNLRDVEHLQKQLEESE-VAKERILQSK 4257
EK A A A K E+ + LE ++K + ++ LQ +L+E+E +A + +
Sbjct: 1818 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIAMKGGKKQV 1877
Query: 4258 KKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRE 4437
+K++ +++ ELE + DS K +K+E ++ E +A ++E R
Sbjct: 1878 QKLEARIKELESELEAEQRKSCDSVKGIRKYERRIKE---LTYQASFPHCQPTEEDRKNL 1934
Query: 4438 TRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSL---EA 4608
+R+ L +++ + + +++ ++ + + +N F K HEL++A+ E+
Sbjct: 1935 SRLQDLADKLQLKVKSY------KKATEEAEEQANNNLTKFRKIQHELDEAEERADIAES 1988
Query: 4609 ELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIR 4788
++N +R + ++ + + R +LE +K++ +R ++ KD E E+ +R L + I
Sbjct: 1989 QVNKLRAKSRDVGSKHEEGKILRAQLEFNQ--VKADIERKLAEKDEEMEQSKRNLQRTID 2046
Query: 4789 DLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQI 4968
L++ LE E R ++ A+ +KK+E + E+E QL ANR E + QI
Sbjct: 2047 TLQSSLEAECRSRNEALRLKKKMEGDLNEMEIQLSQANRQAAEAQKQLKSVHAHLKDCQI 2106
Query: 4969 ECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARK----QXXXXXXXXXX 5136
+ +E+ +A +++ + +R+ ++AE E+LR + E ++RK +
Sbjct: 2107 QLDESVRANDEMKENIAIVERRNNLLQAEVEELRASLEQTERSRKLAEQELLDVSERVQL 2166
Query: 5137 XRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERT 5316
++ G+ + +K++LE +Q C A +K +KA + +L E+
Sbjct: 2167 LHSQNTGLIN-QKKKLEVDASQLQMEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQD 2225
Query: 5317 LNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKT 5496
+ E K+++E++ +D + ++ E E A + Q+ LEA+V+ LE+++ +E ++ +
Sbjct: 2226 TSAHLERMKKNMEQTIKDLQHRLDEAEQIAMKGGKKQVQKLEARVRELENEVEMEQKKSS 2285
Query: 5497 AANRAARRLEKRLNDTTQQ 5553
A + R+ E+R+ + T Q
Sbjct: 2286 EALKGIRKYERRIKELTYQ 2304
Score = 192 bits (487), Expect = 1e-46
Identities = 224/1088 (20%), Positives = 448/1088 (40%), Gaps = 40/1088 (3%)
Frame = +1
Query: 2590 KERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ---------- 2739
K+ LL ++ E E++L+ ERA + +Q ++ + EL++I RL+
Sbjct: 1170 KKSLLSLKARIEELEEELE---AERAARAKVEKQRADLARELEEISERLEEAGGATTAQI 1226
Query: 2740 --TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXD 2913
+ +E E++ RD R+KQ ++V D
Sbjct: 1227 EMNKKREAEFL-KLRRDLEEATLQHEATAAALRKKQADSVADLGEQIDNLQRV------- 1278
Query: 2914 KTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKA---- 3081
K +++ + L Q+ +++ +++ G +
Sbjct: 1279 KQKLEKEKSELRLELDDVVSNMEQVVKSKANLEKMCRSLEDQMQEYKTKSEEGQRTINDV 1338
Query: 3082 ---KGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQL 3252
K +L+ + EL + L + S+L + K+ ++ED K L E++ L + L
Sbjct: 1339 TIQKAKLQTENGELSRQLEEKDSLVSQLTRGKQSYTQQMEDLKRQLEEEIKAKNALAHAL 1398
Query: 3253 MKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVV 3432
+ +Y+EE +Q+ M + + + R ET+ R +
Sbjct: 1399 QSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTE--------- 1449
Query: 3433 AQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQV 3612
+LE+ K + ++ EA E VNA ++E+ +H ++ ++
Sbjct: 1450 -ELEEAKKKLAQRLQEA-------EEAVEAVNAKCSSLEKTKHRLQ-----------NEI 1490
Query: 3613 EELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQ 3792
E+L +E+ + L+K+Q D+ A+ Q+ Q+ K+ + L +++
Sbjct: 1491 EDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELEGSQKEARSLSTELFKLK 1550
Query: 3793 ANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXX 3972
+ ES E+ T+ + + ++EL L E + +++
Sbjct: 1551 NSFEESLENLETMKRENKNLQEELSDLAEQIVEGTKSIHELEK----------------- 1593
Query: 3973 XXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAAR----QGAGEARRKAE 4140
+QLE EK+ L EEAE H E +I + Q E RK
Sbjct: 1594 -----------IRKQLEQEKSELQTSLEEAEASLEHEEGKILRIQLEFNQIKAEIERKLG 1642
Query: 4141 ESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASH 4320
E ++++E+ ++ R V+ LQ LE ++ L+ KKK++ +L + ++L
Sbjct: 1643 EK-DEEMEQAKRNQQRIVDSLQSSLEAETRSRNEALRLKKKMEGDLNEMEIQLSQANRQA 1701
Query: 4321 RDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESD 4500
+++K+ K + + + ++ + ++L D M + + E R L EV+ ++ LE+++
Sbjct: 1702 AEAQKQLKSVHAHLKDSQLQLDESLRANDDMKENIAIVERRNNLLQAEVEELRASLEQTE 1761
Query: 4501 RVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARL 4680
R R+ +QEL D L K+ LEA+ + ++ ++EE + AE+ +
Sbjct: 1762 RSRKLAEQELLDVSERVQLLHSQNTSLLNHKKKLEADASQLQTEVEEAVQECRNAEE-KA 1820
Query: 4681 RLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENEL-ENEKRGKSGAVSHRKKI 4857
+ +T+ A+ +E + + E ++ + + I+DL++ L E E+ G +K+
Sbjct: 1821 KKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIAMKGGKKQVQKL 1880
Query: 4858 ENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXE--YQI---ECEEARQAKEDIAALLRE 5022
E +I ELE +LE R + E YQ C+ + +++++ L
Sbjct: 1881 EARIKELESELEAEQRKSCDSVKGIRKYERRIKELTYQASFPHCQPTEEDRKNLSRLQDL 1940
Query: 5023 ADR---KFRAVEAEREQLRE-ANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEA 5190
AD+ K ++ + E+ E AN L + RK + I+ + +L A
Sbjct: 1941 ADKLQLKVKSYKKATEEAEEQANNNLTKFRK-----IQHELDEAEERADIAESQVNKLRA 1995
Query: 5191 KIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRD 5370
K K +AQ++ Q+ D+ ER L +K E +E+S R+
Sbjct: 1996 KSRDVGSKHEE---------GKILRAQLEFNQVKADI--ERKLAEKDE----EMEQSKRN 2040
Query: 5371 YKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKR------ 5532
+ I L+S ++ R++ AL K + +E LN + + ANR A +K+
Sbjct: 2041 LQRTIDTLQSSLEAECRSRNEALRLK-KKMEGDLNEMEIQLSQANRQAAEAQKQLKSVHA 2099
Query: 5533 -LNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
L D Q ++ RAN++ KE + +N L+ +++E + + + ++E
Sbjct: 2100 HLKDCQIQLDESVRANDEMKENIAIVERRNNLLQAEVEELRASLEQTERSRKLAEQE--- 2156
Query: 5710 LLDANEQL 5733
LLD +E++
Sbjct: 2157 LLDVSERV 2164
Score = 79.0 bits (193), Expect = 1e-12
Identities = 114/588 (19%), Positives = 241/588 (40%), Gaps = 25/588 (4%)
Frame = +1
Query: 4057 EAEGLRAHLEKEIHAARQG--AGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEV 4230
EAE A++++E ++ EARRK E L + + V+ Q L ++E
Sbjct: 845 EAEKEMANMKEEFLKLKEAYAKSEARRKELEEKTVTLLQEKNDLQLQVQSEQDNLCDAEE 904
Query: 4231 AKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDA 4410
E +++SK +++ ++++ + LE+ + + +++K E + +E + + L
Sbjct: 905 RCEGLIKSKIQLEAKIKELTERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAK 964
Query: 4411 MSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKA 4590
+ +E E +V +L E+ + E + + + +++LQ+ Q ++ + V+ L KA
Sbjct: 965 VEKEKHATENKVKNLTEEMAALDEIIAKLTKEKKALQEAHQQTLDDLQSEEDKVNTLTKA 1024
Query: 4591 KRSLEAELNDMRVQMEELEDNLQIA--------------EDARLRLEVTNQALKSESDRA 4728
K LE +++D+ + + + IA ++ ++R+++ K E D
Sbjct: 1025 KTKLEQQVDDVSITFKNDATKIGIAVIWNFVPQLEGSLEQEKKVRMDLERAKRKLEGDLK 1084
Query: 4729 ISNKDV-EAEEKRRGLLKQIRDLENELENEKRGKSGAVSH-RKKIENQIGELEQQLEVAN 4902
++ + + + E ++ L ++++ L + + K +SH KIE+ E ++
Sbjct: 1085 LTQESLMDLENDKQQLEEKLKKLRKKKTRREVMKDFEISHLNSKIED---EQAMSAQLQK 1141
Query: 4903 RLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANE 5082
+LKE Q+ C + + ++ +K +++ + + ++ E E
Sbjct: 1142 KLKE---------------LQVRCAHDNRLFSQVT-IMSPKKKKKKSLLSLKARIEELEE 1185
Query: 5083 GLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQR 5262
L E +R AK+ + +LA + +
Sbjct: 1186 EL--------------------------EAERAARAKVEK---------QRADLARELEE 1210
Query: 5263 KAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALE 5442
++ +LE+ + + +N+K EAE L R +LE A + A AAL
Sbjct: 1211 ISE-RLEEAGGATTAQIEMNKKREAEFLKLRR----------DLEE-ATLQHEATAAALR 1258
Query: 5443 AKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNR 5622
K D + G++ R ++LEK ++ + +D EQ +
Sbjct: 1259 KKQA---DSVADLGEQIDNLQRVKQKLEKEKSELRLELDDVVSNMEQVVK-------SKA 1308
Query: 5623 NLRRQLDEAEDEMSRERTKHRNVQREADD-------LLDANEQLTREL 5745
NL + ED+M +TK QR +D L N +L+R+L
Sbjct: 1309 NLEKMCRSLEDQMQEYKTKSEEGQRTINDVTIQKAKLQTENGELSRQL 1356
>gi|7209643|dbj|BAA92289.1| myosin heavy chain [Seriola dumerili]
Length = 1938
Score = 1095 bits (2831), Expect = 0.0
Identities = 646/1894 (34%), Positives = 1061/1894 (55%), Gaps = 20/1894 (1%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V D +E +L G + ++ + VE DT + +T+ DD+ + NPPKFDKIEDM+ +T+L
Sbjct: 39 FVADADEMYLKGKLVKKEGGKATVE-TDTGKTLTVKEDDIHQRNPPKFDKIEDMAMMTHL 97
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
NE VL+NLKDRY S +IYTYSGLFCVV+NPYK LP+Y ++ ++GKKR E PPHIF+
Sbjct: 98 NEPCVLYNLKDRYASWMIYTYSGLFCVVVNPYKWLPVYDAVVVGAYRGKKRIEAPPHIFS 157
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY++M +RE+QS+L TGESGAGKT NTK+VIQY A +A K A A +
Sbjct: 158 ISDNAYQAMHTDRENQSVLITGESGAGKTVNTKRVIQYFATIAALGAKK---AEATPGKM 214
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
Q G LE Q++ ANP+LEA+GN+KTV+NDNSSRFGKFIRI+F +G +S A+IE
Sbjct: 215 Q--------GSLEDQIVAANPLLEAYGNAKTVRNDNSSRFGKFIRIHFGSAGKLSSADIE 266
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRF-LVNRG-ITLPNV 981
YLLEKSRV Q ERS+HIFYQ++ G E E LL + Y + ++++G IT+ ++
Sbjct: 267 TYLLEKSRVTFQLSAERSYHIFYQLMTG-HKPELLEALLITTNPYDYHMISQGEITVKSI 325
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
DDV+EF +T ++ I+GF +E I ++ AV+ GN++F Q+++ +QA + K
Sbjct: 326 DDVEEFIATDTAIDILGFTAEEKLGIYKLTGAVMHHGNMKFKQKQREEQAEPDGNEEADK 385
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+ +LLGL ++ KA PR+KVG E V K Q Q +V A+ K+ YE++F W+V RI
Sbjct: 386 IAYLLGLNSADMLKALCYPRVKVGNEMVTKGQTVPQVNNSVSALCKSIYEKMFLWMVIRI 445
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 446 NEMLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 504
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA+D +F KL H K
Sbjct: 505 KEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKASDTTFKNKLHDQHLGKTKA 564
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P ++++HF++VHYAG VDY+ WL KN DPLN++VV L Q S++ +A ++
Sbjct: 565 FEKPKPAKGKAEAHFSLVHYAGTVDYNISGWLDKNKDPLNDSVVQLYQKSSNKLLAFLY- 623
Query: 1870 DAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHE 2049
A G A G + + G F+TVS L +E L KLMT LR+T PHFVRC+IPN
Sbjct: 624 -AAHGGADDAAGGGGKKGGKKKGGSFQTVSALFRENLGKLMTNLRSTHPHFVRCLIPNET 682
Query: 2050 KKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDG 2226
K G + + LV+ QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L VIP+ FID
Sbjct: 683 KTPGLMENFLVIHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASVIPEGQFIDN 742
Query: 2227 KESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSR 2406
K++ K++ ++D+D Y+ G +KVFF+ G+L LEE RD KL L+ QA CRG+L R
Sbjct: 743 KKASEKLLGSIDVDHTQYKFGHTKVFFKAGLLGALEEMRDDKLATLVTMTQALCRGYLMR 802
Query: 2407 RLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRA 2586
+ + N +++ ++NW W L+ K+KPLL+ T+ E++ +
Sbjct: 803 KEFVKMMERRESIFSIQYNIRSFMNVKNWPWMNLYFKIKPLLKSAETEKELQQMKENYEK 862
Query: 2587 TKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYI 2766
+ L +E E+K+ ++ E+ +Q Q+ E EN ++ ++ L +LE
Sbjct: 863 MQSDLATALAKKKELEEKMVSLLQEKNDLQLQVASEVENLSDAEERCEGLIKSKIQLEAK 922
Query: 2767 VNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXX 2946
+ + +RL +RK + + +K +
Sbjct: 923 LKETTERLEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 982
Query: 2947 XXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDL 3126
++ L E++ KAK +LE Q+ +LE L
Sbjct: 983 TEEMASQDESIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSL 1042
Query: 3127 NRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEES 3306
+E++ + +LE+ KRKL +L+ +++ + + ++ + ++ K++ E L++ ++E
Sbjct: 1043 EQEKKLRMDLERAKRKLEGDLKLAQESIMDLENDKQQSDEKIKKKEFETSQLLSKIEDEQ 1102
Query: 3307 ANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT 3486
+ +QK+++++Q I+EL E++E ER AR K E R ++ +LE++ + L++ AT
Sbjct: 1103 SLGAQLQKKIKELQARIEELEEEIEAERAARAKVEKQRADLSRELEEI-SERLEEAGGAT 1161
Query: 3487 MLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQL 3663
Q M++K E E +R +E+ E + K + V EL +QI+ ++ + +L
Sbjct: 1162 AAQIEMNKKREAEFQKLRRDLEESTLQHESTASALRKKQADSVAELGEQIDNLQRVKQKL 1221
Query: 3664 EKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLID-- 3837
EK++++ E D++ + + S+ +++K + E L E++ A++DE+ R L D
Sbjct: 1222 EKEKSEYKMEIDDLSSNMEAVAKSKGNLEKMCRTLEDQLSELK---AKNDENVRQLNDIN 1278
Query: 3838 -QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRAR 4014
R + E +R EE+E + + R + K A + +
Sbjct: 1279 AHKARLQTENGEFSRQLEEKEALVSQLTRGKQAFTQQIEELKRHIEEEVKAKNALAHAVQ 1338
Query: 4015 QLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDV 4194
+ + L ++ EE + +A L++ + A + R K E Q+ EEL + +
Sbjct: 1339 SARHDCDLLREQFEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA 1398
Query: 4195 EHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMA 4365
+ LQ E E + + ++K+++Q E+ED +++E + + +K+Q+ F+ +A
Sbjct: 1399 QRLQDAEESIEAVNSKCASLEKTKQRLQGEVEDLMIDVERANSLAANLDKKQRNFDKVLA 1458
Query: 4366 EERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSIS 4545
E + ++ + + +E R T + + N + +HLE R ++LQQE+ D
Sbjct: 1459 EWKQKYEEGQAELEGAQKEARSLSTELFKMKNSYEEALDHLETMKRENKNLQQEISDLTE 1518
Query: 4546 NKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDR 4725
+ GK++HELEKAK+++E E +++ +EE E L+ E LR+++ +K E DR
Sbjct: 1519 QIGETGKSIHELEKAKKTVETEKTEIQSALEEAEGTLEHEEAKILRVQLELNQVKGEVDR 1578
Query: 4726 AISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANR 4905
++ KD E E+ +R + + +++ L+ E R ++ A+ +KK+E + E+E QL ANR
Sbjct: 1579 KLAEKDEEMEQIKRNSQRVMDSMQSTLDAEVRSRNDALRVKKKMEGDLNEMEIQLSHANR 1638
Query: 4906 LKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEG 5085
E + + ++A + +ED+ + +R+ + AE E+LR A E
Sbjct: 1639 QAAEAQKQLRNVQGQLKDALLHLDDAVRGQEDMKEQVVMVERRNGLMVAEIEELRVALEQ 1698
Query: 5086 LMQARKQXXXXXXXXXXXRAKGGGISSEE------KRRLEAKIAQXXXXXXXXQSNCELA 5247
+ RK + G + S+ K++LE+ + Q A
Sbjct: 1699 TERGRK---VAEQELVDASERVGLLHSQNTSLLNTKKKLESDLVQVQSEVDDSIQEARNA 1755
Query: 5248 IDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQ 5427
+K +KA + +L E+ + E K++LE + +D + ++ E E+ A + Q
Sbjct: 1756 EEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEVTVKDLQHRLDEAENLAMKGGKKQ 1815
Query: 5428 MAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKS 5607
+ LE++V+ LE +++ E + + A + R+ E+R+ + T Q E++K+ + ++L++K
Sbjct: 1816 LQKLESRVRELEAEVDAEQRRGSDAVKGVRKYERRVKELTYQTEEDKKNVHRLQDLVDKL 1875
Query: 5608 NLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
LK + +RQ +E+E++ + ++ R VQ E ++
Sbjct: 1876 QLKVKAYKRQAEESEEQANTHLSRLRKVQHEMEE 1909
Score = 132 bits (331), Expect = 1e-28
Identities = 147/813 (18%), Positives = 331/813 (40%), Gaps = 17/813 (2%)
Frame = +1
Query: 3325 QKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEK------VKGDVLDKVDEAT 3486
+K+++ M+ ++++ D+ T K E+ + V EK V +V + D
Sbjct: 850 EKELQQMKENYEKMQSDLATA--LAKKKELEEKMVSLLQEKNDLQLQVASEVENLSDAEE 907
Query: 3487 MLQDLMSRKDEEVNATKRAIEQIQHTME--GKIEEQKAKFSRQVEELHDQIEQHKKQRSQ 3660
+ L+ K + K E+++ E ++ +K K + EL I+ + ++
Sbjct: 908 RCEGLIKSKIQLEAKLKETTERLEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAK 967
Query: 3661 LEKQQNQADQERADMAQEIALLQASRADIDKKRK-IHEAHLMEIQANLAESDEHKRTLID 3837
+EK+++ + + ++ +E+A S A + K++K + EAH + AE D+ TL
Sbjct: 968 VEKEKHATENKVKNLTEEMASQDESIAKLTKEKKALQEAHQQTLDDLQAEEDK-VNTLTK 1026
Query: 3838 QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQ 4017
+ ++D L E+E+ +++R + I ++ +Q
Sbjct: 1027 AKTKLEQQVDDLEGSLEQEKKLRMDLER--------AKRKLEGDLKLAQESIMDLENDKQ 1078
Query: 4018 LEDEKNALLDEKE-EAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDV 4194
DEK + +KE E L + +E E +S+ QL++ K+ +
Sbjct: 1079 QSDEK---IKKKEFETSQLLSKIEDE----------------QSLGAQLQKKIKELQARI 1119
Query: 4195 EHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEER 4374
E L++++E A+ ++ + + + +ELE+ S LE + + KK E++ + R
Sbjct: 1120 EELEEEIEAERAARAKVEKQRADLSRELEEISERLEEAGGATAAQIEMNKKREAEFQKLR 1179
Query: 4375 VAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKD 4554
++++ L ++ + LR ++ DS++
Sbjct: 1180 RDLEESTLQHESTASALRKKQA-------------------------------DSVA--- 1205
Query: 4555 DFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAIS 4734
+ G+ + L++ K+ LE E ++ ++++++L N++ ++ LE + L+ +
Sbjct: 1206 ELGEQIDNLQRVKQKLEKEKSEYKMEIDDLSSNMEAVAKSKGNLEKMCRTLEDQLS---- 1261
Query: 4735 NKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKE 4914
E + K ++Q+ D+ +H+ +++ + GE +QLE L
Sbjct: 1262 ----ELKAKNDENVRQLNDIN--------------AHKARLQTENGEFSRQLEEKEALVS 1303
Query: 4915 EYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA----DRKFRAVEAEREQLREANE 5082
+ E + EE +AK +A ++ A D E E+E E
Sbjct: 1304 QLTRGKQAFTQQIEELKRHIEEEVKAKNALAHAVQSARHDCDLLREQFEEEQEAKAELQR 1363
Query: 5083 GLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQR 5262
G+ +A + + E K++L ++ S C ++
Sbjct: 1364 GMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEESIEAVNSKCASLEKTKQ 1423
Query: 5263 KAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES---GAQSRARAQMA 5433
+ Q ++E + D+ +L + ++++ ++ ++K K E ++ GAQ AR+
Sbjct: 1424 RLQGEVEDLMIDVERANSLAANLDKKQRNFDKVLAEWKQKYEEGQAELEGAQKEARSLST 1483
Query: 5434 ALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNL 5613
L E+ L+ R + L++ ++D T+Q + ++ + ++ +
Sbjct: 1484 ELFKMKNSYEEALD----HLETMKRENKNLQQEISDLTEQIGETGKSIHELEKAKKTVET 1539
Query: 5614 KNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ ++ L+EAE + E K VQ E + +
Sbjct: 1540 EKTEIQSALEEAEGTLEHEEAKILRVQLELNQV 1572
Score = 92.0 bits (227), Expect = 2e-16
Identities = 95/463 (20%), Positives = 203/463 (43%), Gaps = 28/463 (6%)
Frame = +1
Query: 3037 QLLDHEERAKHGVKAKGR----LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKD 3204
+ LDH E K K + L Q+ E + ++ + K +E K ++ + LE+++
Sbjct: 1494 EALDHLETMKRENKNLQQEISDLTEQIGETGKSIHELEKAKKTVETEKTEIQSALEEAEG 1553
Query: 3205 HLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMET 3384
L + K+ + +L + E+ +L DEE M++ R+ Q +D ++ ++
Sbjct: 1554 TLEHEEAKILRVQLELNQVKGEVDRKLAEKDEE------MEQIKRNSQRVMDSMQSTLDA 1607
Query: 3385 ERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHT 3564
E +RN A ++++ L +++ + +A Q + ++ K A+ +
Sbjct: 1608 EVRSRNDALRVKKKMEGDLNEMEIQLSHANRQAAEAQKQLRNVQGQL---KDALLHLDDA 1664
Query: 3565 MEGK--IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASR 3738
+ G+ ++EQ R+ + +IE+ + Q E+ + A+QE D ++ + LL +
Sbjct: 1665 VRGQEDMKEQVVMVERRNGLMVAEIEELRVALEQTERGRKVAEQELVDASERVGLLHSQN 1724
Query: 3739 ADIDKKRKIHEAHLMEIQANLAESDEHKRT--------------LIDQLERSRDELDHLN 3876
+ +K E+ L+++Q+ + +S + R + ++L++ +D HL
Sbjct: 1725 TSLLNTKKKLESDLVQVQSEVDDSIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 1784
Query: 3877 RVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKE 4056
R+++ E ++Q RL A +R R+LE E +A
Sbjct: 1785 RMKKNLEVTVKDLQHRLDEAENLAMKGGKKQLQKLE------SRVRELEAEVDAEQRRGS 1838
Query: 4057 EA-EGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVA 4233
+A +G+R + E+ + E ++ +L++L K V+ ++Q EESE
Sbjct: 1839 DAVKGVRKY-ERRVKELTYQTEEDKKNVH-----RLQDLVDKLQLKVKAYKRQAEESEEQ 1892
Query: 4234 KERILQSKKKIQQELED-------SSMELENVRASHRDSEKRQ 4341
L +K+Q E+E+ + ++ +RA RD+ K +
Sbjct: 1893 ANTHLSRLRKVQHEMEEAQERADIAESQVNKLRAKSRDTGKSE 1935
Score = 69.7 bits (169), Expect = 8e-10
Identities = 94/513 (18%), Positives = 208/513 (40%), Gaps = 20/513 (3%)
Frame = +1
Query: 4261 KIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRET 4440
KI+ L+ + E E ++ + EK Q + +A+++ +K + ++ QE D +
Sbjct: 839 KIKPLLKSAETEKE-LQQMKENYEKMQSDLATALAKKKELEEKMV----SLLQEKNDLQL 893
Query: 4441 RVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELND 4620
+V S + + +E E + + L+ +L+++ +D + EL KR LE E ++
Sbjct: 894 QVASEVENLSDAEERCEGLIKSKIQLEAKLKETTERLEDEEEINAELTAKKRKLEDECSE 953
Query: 4621 MRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAE--EKRRGLLKQIRDL 4794
++ +++LE L E + T +K+ ++ S + A+ ++++ L + +
Sbjct: 954 LKKDIDDLELTLAKVEKEK---HATENKVKNLTEEMASQDESIAKLTKEKKALQEAHQQT 1010
Query: 4795 ENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIEC 4974
++L+ E+ + + K+E Q+ +LE LE +L+ + + + +
Sbjct: 1011 LDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKR-------KLEGDL 1063
Query: 4975 EEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGG 5154
+ A+++ D+ +++D K + E E QL
Sbjct: 1064 KLAQESIMDLENDKQQSDEKIKKKEFETSQLLS--------------------------- 1096
Query: 5155 GISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERT------ 5316
E+++ L A++ + E I+ +R A+ ++E+ DLS E
Sbjct: 1097 --KIEDEQSLGAQLQKKIKELQARIEELEEEIEAERAARAKVEKQRADLSRELEEISERL 1154
Query: 5317 ------------LNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYL 5460
+N+K EAE Q L R + + S + + +A L ++ L
Sbjct: 1155 EEAGGATAAQIEMNKKREAEFQKLRRDLEESTLQHESTASALRKKQADSVAELGEQIDNL 1214
Query: 5461 EDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQL 5640
+ +EK+ L + + + ++ ++ L + KN RQL
Sbjct: 1215 QRVKQKLEKEKSEYKMEIDDLSSNMEAVAKSKGNLEKMCRTLEDQLSELKAKNDENVRQL 1274
Query: 5641 DEAEDEMSRERTKHRNVQREADDLLDANEQLTR 5739
++ +R +T++ R+ ++ QLTR
Sbjct: 1275 NDINAHKARLQTENGEFSRQLEEKEALVSQLTR 1307
Score = 36.2 bits (82), Expect = 9.9
Identities = 32/160 (20%), Positives = 73/160 (45%), Gaps = 16/160 (10%)
Frame = +1
Query: 5311 RTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQE 5490
+ L + E EK+ L++ +Y+ ++L + + + + + + QL V +
Sbjct: 841 KPLLKSAETEKE-LQQMKENYEKMQSDLATALAKKKELEEKMVSLLQEKNDLQLQVASEV 899
Query: 5491 KTAANRAAR---------RLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLD 5643
+ ++ R +LE +L +TT++ EDE+ N + K + L++ +D
Sbjct: 900 ENLSDAEERCEGLIKSKIQLEAKLKETTERLEDEEEINAELTAKKRKLEDECSELKKDID 959
Query: 5644 EAEDEMSR-ERTKH------RNVQREADDLLDANEQLTRE 5742
+ E +++ E+ KH +N+ E ++ +LT+E
Sbjct: 960 DLELTLAKVEKEKHATENKVKNLTEEMASQDESIAKLTKE 999
>gi|32566139|ref|NP_506065.2| MYOsin heavy chain structural gene,
SUPpressor SUP-3 (225.5 kD) (myo-3) [Caenorhabditis
elegans]
gi|127737|sp|P12844|MYSA_CAEEL Myosin heavy chain A (MHC A)
gi|6799|emb|CAA30856.1| myosin heavy chain 3 [Caenorhabditis elegans]
gi|33300386|emb|CAB01576.2| C. elegans MYO-3 protein (corresponding
sequence K12F2.1) [Caenorhabditis elegans]
Length = 1969
Score = 1095 bits (2831), Expect = 0.0
Identities = 644/1940 (33%), Positives = 1058/1940 (54%), Gaps = 28/1940 (1%)
Frame = +1
Query: 16 YLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTIS 195
+L + R A A A + +K CW+PD +GF+ I+ T ++V V V Q+T+
Sbjct: 16 FLGISREARAATAA-RPFDSKKNCWIPDPEDGFVAAEIQSTTGEQVTVVTVK-GNQITVK 73
Query: 196 RDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLP 375
+D Q+ NPPKFDK EDM+ LT+LNEASVL NLKDRY +IYTYSGLFCVVINPYK+LP
Sbjct: 74 KDQCQEMNPPKFDKTEDMANLTFLNEASVLGNLKDRYKDLMIYTYSGLFCVVINPYKRLP 133
Query: 376 IYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVI 555
IYSE +I+ F GK+R+EMPPH+FA++D AYR+M+Q++E+QS+L TGESGAGKTENTKKVI
Sbjct: 134 IYSESVIKHFMGKRRNEMPPHLFAVSDEAYRNMVQDKENQSMLITGESGAGKTENTKKVI 193
Query: 556 QYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDN 735
Y A + GAT+ S A G LE Q++Q NP+LEAFGN+KTV+N+N
Sbjct: 194 SYFA-IVGATQAASGKEAKDGK---------KGGTLEEQIVQTNPVLEAFGNAKTVRNNN 243
Query: 736 SSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSE 915
SSRFGKFIR +F SG ++G +IE YLLEKSRV+RQA ER +HIFYQI+ G + +
Sbjct: 244 SSRFGKFIRTHFSGSGKLAGGDIEHYLLEKSRVVRQAPGERCYHIFYQIMSGNDPSLRGK 303
Query: 916 YLLEG-VDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 1092
L + Y F +T+ +DD +E T + IMGF D+E + R + ++ +G
Sbjct: 304 LKLSNDITYYHFCSQAELTIEGMDDKEEMRLTQEAFDIMGFEDNETMDLYRSTAGIMHMG 363
Query: 1093 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA 1272
++F Q + +QA + +LG+ E KA +PR++VG E+VNK QN EQ
Sbjct: 364 EMKFKQRPREEQAEPDGEEDALNAAAMLGIQAEEFLKALTKPRVRVGTEWVNKGQNLEQV 423
Query: 1273 EFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICIN 1452
+AV +AKA Y R+FKW++TR NK+LD + FIG+LDIAGFEIFD+NSFEQ+ IN
Sbjct: 424 NWAVSGLAKAIYARMFKWIITRCNKTLDAKEIERKHFIGVLDIAGFEIFDLNSFEQLWIN 483
Query: 1453 YTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECL 1632
+ NE+LQQ FN+ MF+LEQEEY+REGI W FIDFGLDLQ I+LIEKP+G++++LDEEC+
Sbjct: 484 FVNERLQQFFNHHMFVLEQEEYKREGIAWTFIDFGLDLQACIELIEKPLGIISILDEECI 543
Query: 1633 FPKANDKSFVEKLQKTH-NKHPKFIVP----DMRSKSHFAVVHYAGRVDYSADQWLMKNM 1797
PKA D ++ +KL H KHP F P + +HFA+VHYAG V Y+A +L KN
Sbjct: 544 VPKATDMTYAQKLLDQHLGKHPNFQKPKPPKGKQGDAHFAIVHYAGTVRYNATNFLEKNK 603
Query: 1798 DPLNENVVGLMQNSTD-PFVAGIWKD--AEFAGICAAEMNETAFGMRSRKGMFRTVSQLH 1968
DPLN+ V L+++STD + IW+D + AA+ +TA G R + F TVS ++
Sbjct: 604 DPLNDTAVALLKHSTDNSLMLDIWQDYQTQEEAAEAAKAGQTAGGKRGKSSSFATVSMIY 663
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
+E L LM L T PHF+RCIIPN +K SG I+S LVL QL CNGVLEGIRICR+GFPN
Sbjct: 664 RESLNNLMNMLYQTHPHFIRCIIPNEKKASGVIDSALVLNQLTCNGVLEGIRICRKGFPN 723
Query: 2149 RVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNL----YRIGQSKVFFRTG 2316
R+ + +F+HRY IL D ++ D K++ ++ + +D NL +++G++K+FF+ G
Sbjct: 724 RMLYPDFKHRYAILAADAAKES--DPKKASVGILDKISVDGNLTDEEFKVGETKIFFKAG 781
Query: 2317 VLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQ 2496
VLA LE+ RD L+ ++ FQ++ R +L++ N A+ LR W+
Sbjct: 782 VLAKLEDLRDEILSRIVTMFQSRIRSYLAKAEVRRRYEQQTGLLVVQRNVRAWCTLRTWE 841
Query: 2497 WWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQ 2676
W++LF KVKP+L+ + + + +++ +E + + E + E ++ ++ E+ +
Sbjct: 842 WFKLFGKVKPMLKAGKEQEAMGELAVKIQKLEEAVQRGEIARSQLESQVADLVEEKNALF 901
Query: 2677 EQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVR 2856
L+ E N A+ ++ +L LE ++D+ +L ++K + +
Sbjct: 902 LSLETEKANLADAEERNEKLNQLKATLESKLSDITGQLEDMQERNEDLARQKKKTDQELS 961
Query: 2857 DXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTT 3036
D +K + D +A L
Sbjct: 962 DTKKHVQDLELSLRKAEQEKQSRDHNIRSLQDEMANQDEAVAKLNKEKKHQEESNRKLNE 1021
Query: 3037 QLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAE 3216
L E++ H K + +LE Q+ ELE++++RE++ + ++E+ KRK+ +L+ +++++ E
Sbjct: 1022 DLQSEEDKVNHLEKIRNKLEQQMDELEENIDREKRSRGDIEKAKRKVEGDLKVAQENIDE 1081
Query: 3217 KMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNA 3396
+ ++ L +++E+L H + E ++ + +Q+ ++++ EL E++E ERN+
Sbjct: 1082 ITKQKHDVETTLKRKEEDLHHTNAKLAENNSIIAKLQRLIKELTARNAELEEELEAERNS 1141
Query: 3397 RNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEG 3573
R K++ +R E +LE++ + L++ AT Q + +++ E+ +R E+ E
Sbjct: 1142 RQKSDRSRSEAERELEELT-ERLEQQGGATAAQLEANKKREAEIAKLRREKEEDSLNHET 1200
Query: 3574 KIEEQKAKFSRQVEELHDQIE--QHKKQRSQLEKQQNQADQERADMAQEIALLQASRADI 3747
I + + V EL +Q+E Q K +S+ EK + Q D E + A + + SR D+
Sbjct: 1201 AISSLRKRHGDSVAELTEQLETLQKLKAKSEAEKSKLQRDLEESQHATDSEV--RSRQDL 1258
Query: 3748 DKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRL 3927
+K K E E+Q E + R +E LNR EE ++ ++ R
Sbjct: 1259 EKALKTIEVQYSELQTKADEQSRQLQDFAALKNRLNNENSDLNRSLEEMDNQLNSLHRLK 1318
Query: 3928 ATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAAR 4107
+T +R + A A+ LE E L + +E +A L ++I
Sbjct: 1319 STLQSQLDETRRNYDEESRERQALAATAKNLEHENTILREHLDEEAESKADLTRQISKLN 1378
Query: 4108 QGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKK---KIQQEL 4278
+ + + + +LEE+ +Q+ + +E +I +K K+ Q+L
Sbjct: 1379 AEIQQWKARFDSEGLNKLEEIEAAKKALQLKVQELTDTNEGLFAKIASQEKVRFKLMQDL 1438
Query: 4279 EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLL 4458
+D+ ++E A EK +++FES +AE + + DA ++ R T +
Sbjct: 1439 DDAQSDVEKAAAQVAFYEKHRRQFESIIAEWKKKTDDLSSELDAAQRDNRQLSTDLFKAK 1498
Query: 4459 NEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQME 4638
D + E+L+ + R +SL QE++D + G++V EL+K R LE E +++ ++
Sbjct: 1499 TANDELAEYLDSTRRENKSLAQEVKDLTDQLGEGGRSVAELQKIVRKLEVEKEELQKALD 1558
Query: 4639 ELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEK 4818
E E L+ E LR ++ ++SE ++ I K+ E E RR + + ++ LE E
Sbjct: 1559 EAEAALEAEEAKVLRAQIEVSQIRSEIEKRIQEKEEEFENTRRNHQRALESMQATLEAET 1618
Query: 4819 RGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKE 4998
+ K A+ +KK+E+ I +LE L+ ANR + E Q + EE ++ K+
Sbjct: 1619 KQKEEALRIKKKLESDINDLEIALDHANRAYADAQKTIKKYMETVQELQFQIEEEQRQKD 1678
Query: 4999 DIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSE--- 5169
+I ++++ +++E+++L + E +AR+ R + +++
Sbjct: 1679 EIREQFLASEKRNAILQSEKDELAQQAEAAERARRN---AEAECIELREQNNDLNAHVSA 1735
Query: 5170 ---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAE 5340
++R+LE ++ + + A+++ +KA ++ +L E+ + E
Sbjct: 1736 LTGQRRKLEGELLAAHAELEEIANELKNAVEQGQKASADAARLAEELRQEQEHSMHIERI 1795
Query: 5341 KQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARR 5520
++ LE ++ + ++ + E+ A + +A LEA+++ +E +L+ E + + R+
Sbjct: 1796 RKGLELQIKEMQIRLDDAENAALKGGKKIIAQLEARIRAIEQELDGEQRRHQDTEKNWRK 1855
Query: 5521 LEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQ-- 5694
E+R+ + Q +EK+ E+ EL++K K + +RQ++EAE+ + K++ +
Sbjct: 1856 AERRVKEVEFQVVEEKKNEERLTELVDKLQCKLKIFKRQVEEAEEVAASNLNKYKVLTAQ 1915
Query: 5695 -READDLLDANEQLTRELMN 5751
+A++ D E ++ N
Sbjct: 1916 FEQAEERADIAENALSKMRN 1935
>gi|9971579|dbj|BAB12571.1| myosin heavy chain [Pennahia argentata]
Length = 1930
Score = 1094 bits (2829), Expect = 0.0
Identities = 638/1892 (33%), Positives = 1043/1892 (54%), Gaps = 17/1892 (0%)
Frame = +1
Query: 85 CWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTY 264
C+V D E +L I ++ +V V+++DT + T+ DDV NPPKFDKIEDM+ +T+
Sbjct: 38 CYVADVKELYLKALITKKDGAKVTVKVLDTEEERTVKEDDVTPMNPPKFDKIEDMAMMTH 97
Query: 265 LNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIF 444
LNEASVL+NLK+RY + +IYTYSGLFC +NPYK LP+Y +++ ++GKKR E PPHIF
Sbjct: 98 LNEASVLYNLKERYAAWMIYTYSGLFCATVNPYKWLPVYDSEVVNAYRGKKRMEAPPHIF 157
Query: 445 AIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVA-GATRNKSLNAAAQQN 621
+++D A++ ML +RE+QS+L TGESGAGKT NTK+VIQY A ++ G + + +
Sbjct: 158 SVSDNAFQFMLIDRENQSVLITGESGAGKTVNTKRVIQYFATISVGGEKKRDTSK----- 212
Query: 622 IVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGAN 801
G LE Q++ ANP+LEA+GN+KTV+NDNSSRFGKFIR++F +G ++ A+
Sbjct: 213 -----------GSLEDQIIAANPLLEAYGNAKTVRNDNSSRFGKFIRVHFGATGKLASAD 261
Query: 802 IEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRF-LVNRG-ITLP 975
IE YLLEKSRV Q DER +HIFYQ++ E E L + Y F + + G IT+
Sbjct: 262 IETYLLEKSRVTFQLPDERGYHIFYQMMTN-HKPELIEMSLITTNPYDFPMCSMGQITVA 320
Query: 976 NVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVI 1155
++DD E +T N++ I+GF DE SI ++ AVL G+++F Q+++ +QA
Sbjct: 321 SIDDKVELEATDNAIDILGFTSDEKMSIYKMTGAVLHHGSMKFKQKQREEQAEPDGTEDA 380
Query: 1156 QKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVT 1335
KV +LLGL ++ KA PR+KVG E+V K Q Q +V A+AK+ YE++F W+V
Sbjct: 381 DKVAYLLGLNSADMLKALCYPRVKVGNEYVTKGQTVPQVNNSVTALAKSIYEKMFLWMVI 440
Query: 1336 RINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEE 1515
RIN+ LD T + FIG+LDIAGFEIFD N+ EQ+CIN+TNEKLQQ FN+TMF+LEQEE
Sbjct: 441 RINEMLD-TKQARQFFIGVLDIAGFEIFDFNTLEQLCINFTNEKLQQFFNHTMFVLEQEE 499
Query: 1516 YQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKH 1692
Y++EGI W+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H K+
Sbjct: 500 YKKEGIVWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKN 559
Query: 1693 PKFIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGI 1863
F P ++++HF++VHYAG VDY+ WL KN DPLNE+VV L Q S+
Sbjct: 560 KAFEKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNESVVQLYQKSS------- 612
Query: 1864 WKDAEFAGICAAEMNETAFGMRSRK--GMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCII 2037
+ + + E G + +K G +TVS +E L KLMT LR+T PHFVRC+I
Sbjct: 613 ---VKLLPVLYPPVVEETGGKKGKKKGGSMQTVSAAFRENLGKLMTNLRSTHPHFVRCLI 669
Query: 2038 PNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-N 2214
PN K G + + LV+ QLRCNGVLEGIRICR+GFP+R+P+ +F+ RY++L VIP
Sbjct: 670 PNESKTPGLMENFLVIHQLRCNGVLEGIRICRKGFPSRIPYADFKQRYKVLNASVIPDGQ 729
Query: 2215 FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRG 2394
F+D K++ K++ ++D+D + YR G +KVFF+ G+L LEE RD KL AL+ QA CRG
Sbjct: 730 FMDNKKASEKLLGSIDVDHDQYRFGHTKVFFKAGLLGTLEEMRDEKLAALVTMTQALCRG 789
Query: 2395 FLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDD 2574
++ R+ + N ++ ++NW W +++ K+KP+L+ T+ E+ +
Sbjct: 790 YVMRKEFVKMMERREAIYTIQYNVRSFTNVKNWPWMKVYYKIKPMLKSAETEKELANMKE 849
Query: 2575 ELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQE 2754
K L +E E+K+ ++ E+ +Q Q+ ESEN ++ ++ L +
Sbjct: 850 NYEKMKTDLATALAKKKELEEKMVSIVQEKNDLQLQVASESENLSDAEERCEGLIKSKIQ 909
Query: 2755 LEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQX 2934
+E + + +RL +RK + + +K +
Sbjct: 910 MEAKLKETSERLEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 969
Query: 2935 XXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHEL 3114
D+ L E++ KAK +LE Q+ +L
Sbjct: 970 VKNLTEEMASQDDSLAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDL 1029
Query: 3115 EQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRY 3294
E L +E++ + +LE+ KRKL +L+ +++ + + ++ + +L K+D E+ L++
Sbjct: 1030 EGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDLENDKQQTDEKLKKKDFEISQLLSKI 1089
Query: 3295 DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKV 3474
++E + +QK+++++Q I+EL E++E ER AR K E R ++ +LE++ + L++
Sbjct: 1090 EDEQSLGAQLQKKIKELQARIEELEEEIEAERAARAKVEKQRADLSRELEEI-SERLEEA 1148
Query: 3475 DEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQ 3651
AT Q M++K E E +R +E+ E + K + V EL +QI+ ++
Sbjct: 1149 GGATASQIEMNKKREAEFQKLRRDLEESTLQHEATAAALRKKQADSVAELGEQIDNLQRV 1208
Query: 3652 RSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTL 3831
+ +LEK++++ E D++ + + ++ +++K + E L E++ E+ +
Sbjct: 1209 KQKLEKEKSEYKMEIDDLSSNMEAVAKAKGNLEKMCRTLEDQLSELKTKNDENVRQINDM 1268
Query: 3832 IDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRA 4011
Q R E R EE+E + + R + K A +
Sbjct: 1269 SGQRARLLTENGEFTRQVEEKEALVSQLTRGKQAFTQQIEELKRQIEEEVKAKNALAHGV 1328
Query: 4012 RQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRD 4191
+ + + L ++ EE + +A L++ + A + R K E Q+ EEL + +
Sbjct: 1329 QSARHDCDLLREQFEEEQEAKAELQRGMSKANSEVAQWRSKYETDAIQRTEELEEAKKKL 1388
Query: 4192 VEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQM 4362
+ LQ E+ E + + ++K+++Q E+ED +++E + +K+Q+ F+ +
Sbjct: 1389 AQRLQDAEEQIEAVNSKCASLEKTKQRLQSEVEDLMIDVERANGLAANLDKKQRNFDKVL 1448
Query: 4363 AEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSI 4542
AE + ++ + + +E R T + + N + + LE R ++LQQE+ D
Sbjct: 1449 AEWKQKYEEGQAELEGAQKEARSLGTELFKMKNSYEESLDQLETMKRENKNLQQEISDLT 1508
Query: 4543 SNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESD 4722
+ GK++HELEKAK+ +E E ++++ +EE E L+ E LR+++ +K E D
Sbjct: 1509 EQIGETGKSIHELEKAKKQVETEKSEIQTALEEAEGTLEHEESKILRVQLELNQVKGEVD 1568
Query: 4723 RAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVAN 4902
R ++ KD E E+ +R + I +++ L++E R ++ A+ +KK+E + E+E QL AN
Sbjct: 1569 RKLAEKDEEMEQIKRNSQRVIDSMQSTLDSEVRSRNDALRIKKKMEGDLNEMEIQLSHAN 1628
Query: 4903 RLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANE 5082
R E + Q+ ++A +A++D +R+ + AE E+LR A E
Sbjct: 1629 RQAAESQKQLRNVQAQLKDAQLHLDDAVRAQDDFKEQAAMVERRNGLMMAEIEELRVALE 1688
Query: 5083 GLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAID 5253
++RK Q K++LEA + Q A +
Sbjct: 1689 QTERSRKVAEQELVDASERVGLLHSQNTSLMNTKKKLEADLVQIQGEVDDTVQEARNAEE 1748
Query: 5254 KQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMA 5433
K +KA + +L E+ + E K++LE + +D + ++ E E+ A + Q+
Sbjct: 1749 KAKKAITDAAMMAEELKKEQDTSSHLERMKKNLEVAVKDLQHRLDEAENLAMKGGKKQLQ 1808
Query: 5434 ALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNL 5613
LE++V+ LE ++ E + A + R+ E+R+ + T Q E++K+ + ++L++K L
Sbjct: 1809 KLESRVRELEAEVEAEQRRGGDAVKGVRKYERRVKELTYQTEEDKKNVARLQDLVDKLQL 1868
Query: 5614 KNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
K + +RQ +EAE++ + +K R +Q E ++
Sbjct: 1869 KVKGYKRQAEEAEEQANVHLSKCRKIQHELEE 1900
Score = 129 bits (325), Expect = 7e-28
Identities = 159/879 (18%), Positives = 361/879 (40%), Gaps = 30/879 (3%)
Frame = +1
Query: 3166 KRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDM 3345
K LL LE+ +D EK+ + + Q + R ++ + + E + +Q +R
Sbjct: 761 KAGLLGTLEEMRD---EKLAALVTMT-QALCRGYVMRKEFVKMMERREAIYTIQYNVRSF 816
Query: 3346 QTT-----------IDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATML 3492
I + + ETE+ N E EK+K D+ + + L
Sbjct: 817 TNVKNWPWMKVYYKIKPMLKSAETEKELANMKE--------NYEKMKTDLATALAKKKEL 868
Query: 3493 QDLMSRKDEEVN-------ATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQ 3651
++ M +E N + + + EG I+ K + +++E +++E ++
Sbjct: 869 EEKMVSIVQEKNDLQLQVASESENLSDAEERCEGLIKS-KIQMEAKLKETSERLEDEEEI 927
Query: 3652 RSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTL 3831
++L ++ + + E +++ ++I L+ + A ++K++ E + + +A D
Sbjct: 928 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMASQD------ 981
Query: 3832 IDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRA 4011
D L ++ +E++ Q+ L T+L+
Sbjct: 982 -----------DSLAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLE------- 1023
Query: 4012 RQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAE-----ESVNQQLEELRK 4176
+Q++D + +L EK+ LR LE+ A R+ G+ + E E+ QQ +E K
Sbjct: 1024 QQVDDLEGSLEQEKK----LRMDLER---AKRKLEGDLKLAQESIMDLENDKQQTDEKLK 1076
Query: 4177 KNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFES 4356
K ++ L ++E+ + ++ + K++Q +E+ E+E RA+ EK++
Sbjct: 1077 KKDFEISQLLSKIEDEQSLGAQLQKKIKELQARIEELEEEIEAERAARAKVEKQRADLSR 1136
Query: 4357 QMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQD 4536
++ E +++A + + + RE L +++ E + + +L+++ D
Sbjct: 1137 ELEEISERLEEAGGATASQIEMNKKREAEFQKLRRDLE---ESTLQHEATAAALRKKQAD 1193
Query: 4537 SISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSE 4716
S++ + G+ + L++ K+ LE E ++ ++++++L N++ A+ LE + L+ +
Sbjct: 1194 SVA---ELGEQIDNLQRVKQKLEKEKSEYKMEIDDLSSNMEAVAKAKGNLEKMCRTLEDQ 1250
Query: 4717 SDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEV 4896
E + K ++QI D+ + R ++ + GE +Q+E
Sbjct: 1251 LS--------ELKTKNDENVRQINDMSGQ--------------RARLLTENGEFTRQVEE 1288
Query: 4897 ANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA----DRKFRAVEAEREQ 5064
L + E + + EE +AK +A ++ A D E E+E
Sbjct: 1289 KEALVSQLTRGKQAFTQQIEELKRQIEEEVKAKNALAHGVQSARHDCDLLREQFEEEQEA 1348
Query: 5065 LREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCEL 5244
E G+ +A + + E K++L ++ S C
Sbjct: 1349 KAELQRGMSKANSEVAQWRSKYETDAIQRTEELEEAKKKLAQRLQDAEEQIEAVNSKCAS 1408
Query: 5245 AIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES---GAQSR 5415
+++ Q ++E + D+ L + ++++ ++ ++K K E ++ GAQ
Sbjct: 1409 LEKTKQRLQSEVEDLMIDVERANGLAANLDKKQRNFDKVLAEWKQKYEEGQAELEGAQKE 1468
Query: 5416 ARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKEL 5595
AR+ L E+ L+ + R + L++ ++D T+Q + ++ + ++
Sbjct: 1469 ARSLGTELFKMKNSYEESLD----QLETMKRENKNLQQEISDLTEQIGETGKSIHELEKA 1524
Query: 5596 LEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
++ + ++ L+EAE + E +K VQ E + +
Sbjct: 1525 KKQVETEKSEIQTALEEAEGTLEHEESKILRVQLELNQV 1563
Score = 99.8 bits (247), Expect = 7e-19
Identities = 123/583 (21%), Positives = 249/583 (42%), Gaps = 22/583 (3%)
Frame = +1
Query: 3046 DHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMG 3225
D +R + +AK +L +L + E+ + + LE+ K++L +E+ED + G
Sbjct: 1373 DAIQRTEELEEAKKKLAQRLQDAEEQIEAVNSKCASLEKTKQRLQSEVEDLMIDVERANG 1432
Query: 3226 KVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNK 3405
L+ + D+ L +Y+E A + QK+ R + T + +++ E + ++
Sbjct: 1433 LAANLDKKQRNFDKVLAEWKQKYEEGQAELEGAQKEARSLGTELFKMKNSYE---ESLDQ 1489
Query: 3406 AEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEE 3585
E +RE L++ D+ +++ E + + ++V K I+ EG +E
Sbjct: 1490 LETMKREN-KNLQQEISDLTEQIGETGKSIHELEKAKKQVETEKSEIQTALEEAEGTLEH 1548
Query: 3586 QKAKFSR---QVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQA-SRADIDK 3753
+++K R ++ ++ ++++ ++ + +Q + Q D Q + SR D +
Sbjct: 1549 EESKILRVQLELNQVKGEVDRKLAEKDEEMEQIKRNSQRVIDSMQSTLDSEVRSRNDALR 1608
Query: 3754 KRKIHEAHLMEIQANL-------AESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFAN 3912
+K E L E++ L AES + R + QL+ ++ LD R +++ + A
Sbjct: 1609 IKKKMEGDLNEMEIQLSHANRQAAESQKQLRNVQAQLKDAQLHLDDAVRAQDDFKEQAAM 1668
Query: 3913 MQRR--LATAXXXXXXXXXXXXXXTRLKIAN------INRARQLEDEKNALLDEKEEAEG 4068
++RR L A +R K+A R L + +L++ K++ E
Sbjct: 1669 VERRNGLMMAEIEELRVALEQTERSR-KVAEQELVDASERVGLLHSQNTSLMNTKKKLEA 1727
Query: 4069 LRAHLEKEIHAARQGAGEARRKAEESVNQ--QLEELRKKNLRDVEHLQKQLEESEVAKER 4242
++ E+ Q A A KA++++ + E KK HL++ + EVA
Sbjct: 1728 DLVQIQGEVDDTVQEARNAEEKAKKAITDAAMMAEELKKEQDTSSHLERMKKNLEVAV-- 1785
Query: 4243 ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQE 4422
K +Q L+ E EN+ + + +K+ +K ES++ E V+ +
Sbjct: 1786 -----KDLQHRLD----EAENL--AMKGGKKQLQKLESRVRELEAEVEAEQRRGGDAVKG 1834
Query: 4423 LRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNK-DDFGKNVHELEKAKRS 4599
+R E RV L + E D+ + Q+L D + K + + E E+
Sbjct: 1835 VRKYERRVKELTYQT--------EEDKKNVARLQDLVDKLQLKVKGYKRQAEEAEEQANV 1886
Query: 4600 LEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRA 4728
++ ++ ++EE E+ IAE +L V ++ + D A
Sbjct: 1887 HLSKCRKIQHELEEAEERADIAETQVNKLRVKSRDIGKGKDAA 1929
Score = 69.7 bits (169), Expect = 8e-10
Identities = 98/516 (18%), Positives = 210/516 (39%), Gaps = 28/516 (5%)
Frame = +1
Query: 4282 DSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLN 4461
++ EL N++ ++ EK + + +A+++ +K + ++ QE D + +V S
Sbjct: 839 ETEKELANMKENY---EKMKTDLATALAKKKELEEKMV----SIVQEKNDLQLQVASESE 891
Query: 4462 EVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE 4641
+ +E E + + ++ +L+++ +D + EL KR LE E ++++ +++
Sbjct: 892 NLSDAEERCEGLIKSKIQMEAKLKETSERLEDEEEINAELTAKKRKLEDECSELKKDIDD 951
Query: 4642 LEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAE--EKRRGLLKQIRDLENELENE 4815
LE L E + T +K+ ++ S D A+ ++++ L + + ++L+ E
Sbjct: 952 LELTLAKVEKEK---HATENKVKNLTEEMASQDDSLAKLTKEKKALQEAHQQTLDDLQAE 1008
Query: 4816 KRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAK 4995
+ + + K+E Q+ +LE LE +L+ + +AK
Sbjct: 1009 EDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDL---------------------ERAK 1047
Query: 4996 EDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEK 5175
+ L+ A +E +++Q + E+
Sbjct: 1048 RKLEGDLKLAQESIMDLENDKQQ--------------------------------TDEKL 1075
Query: 5176 RRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLE 5355
++ + +I+Q QS K ++ Q ++E++ ++ ER K E ++ L
Sbjct: 1076 KKKDFEISQLLSKIEDEQSLGAQLQKKIKELQARIEELEEEIEAERAARAKVEKQRADLS 1135
Query: 5356 RSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRA-ARRLEKR 5532
R + ++ E GA + EA+ Q L L +E T + A A L K+
Sbjct: 1136 RELEEISERLEEA-GGATASQIEMNKKREAEFQKLRRDL----EESTLQHEATAAALRKK 1190
Query: 5533 LNDTTQQFEDEKRANEQAKELLEK-------------SNLK-----NRNLRRQLDEAEDE 5658
D+ + ++ ++ K+ LEK SN++ NL + ED+
Sbjct: 1191 QADSVAELGEQIDNLQRVKQKLEKEKSEYKMEIDDLSSNMEAVAKAKGNLEKMCRTLEDQ 1250
Query: 5659 MSRERTKHRNVQREADD-------LLDANEQLTREL 5745
+S +TK+ R+ +D LL N + TR++
Sbjct: 1251 LSELKTKNDENVRQINDMSGQRARLLTENGEFTRQV 1286
>gi|38488753|ref|NP_942118.1| myosin, heavy polypeptide 6, cardiac
muscle, alpha; atrial myosin heavy chain [Danio rerio]
gi|37720046|gb|AAN71741.1| atrial myosin heavy chain [Danio rerio]
Length = 1936
Score = 1092 bits (2824), Expect = 0.0
Identities = 630/1894 (33%), Positives = 1050/1894 (55%), Gaps = 19/1894 (1%)
Frame = +1
Query: 85 CWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTY 264
C+V D+ ++ G I+ + +V V+ D R VT+ DV NPPKFDKIEDM+ LT+
Sbjct: 37 CFVVDEKVEYVKGQIQNKDGGKVTVKTED-GRTVTVKDGDVHPQNPPKFDKIEDMAMLTF 95
Query: 265 LNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIF 444
L+E +VL NLK+RY + +IYTYSGLFCV +NPYK LP+Y D++ ++GKKR E PPHIF
Sbjct: 96 LHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYDADVVAAYRGKKRTEAPPHIF 155
Query: 445 AIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNI 624
+I+D AY+ ML +RE+QS+L TGESGAGKT NTK+VIQY A +A A + +++
Sbjct: 156 SISDNAYQYMLTDRENQSVLITGESGAGKTVNTKRVIQYFASIAAAGGSTGKKDSSK--- 212
Query: 625 VQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANI 804
G LE Q++QANP LEAFGN+KT++NDNSSRFGKFIRI+F SG +S A+I
Sbjct: 213 ----------GTLEDQIIQANPALEAFGNAKTLRNDNSSRFGKFIRIHFGTSGKLSSADI 262
Query: 805 EFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYL-----LEGVDNYRFLVNRGIT 969
E YLLEKSRV Q + ER++HIF+QIL + EK E L +Y ++ +T
Sbjct: 263 ETYLLEKSRVTFQLKSERNYHIFFQIL----SNEKPELLDMLLITNNPYDYSYISQGEVT 318
Query: 970 LPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDR 1149
+ +++D +E +T + ++GF +E + ++ A++ GN++F Q+++ +QA
Sbjct: 319 VSSINDNEELIATDKAFDVLGFTSEEKMGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTE 378
Query: 1150 VIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWL 1329
K +L+GL +L K PR+KVG E+V K Q+ +Q +++ A+AK+ YE++F W+
Sbjct: 379 DADKAAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVDQVYYSIGALAKSVYEKMFNWM 438
Query: 1330 VTRINKSLD-RTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILE 1506
V RIN+SLD + HRQ FIG+LDIAGFEIFD N+FEQ+CIN+TNEKLQQ FN+ MF+LE
Sbjct: 439 VVRINQSLDTKQHRQ--YFIGVLDIAGFEIFDFNTFEQLCINFTNEKLQQFFNHHMFVLE 496
Query: 1507 QEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH- 1683
QEEY++EGI+W+FIDFG+DLQ IDLIEKP+G++++L+EEC+FPKA+D++F KL H
Sbjct: 497 QEEYKKEGIDWEFIDFGMDLQSCIDLIEKPLGIMSILEEECMFPKASDQTFKAKLYDNHL 556
Query: 1684 ---NKHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFV 1854
N K ++++HFA+ HYAG VDY+ WL+KN DPLNE VVGL Q S+ +
Sbjct: 557 GKTNIFQKPRAVKGKAEAHFALSHYAGTVDYNIAGWLVKNKDPLNETVVGLYQKSSLKLL 616
Query: 1855 AGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCI 2034
+ ++ + +AG E G + + F+TVS LH+E L KLMT L+ T PHFVRC+
Sbjct: 617 SLLF--SSYAGSDGGE-KSGGKGAKKKGSSFQTVSALHRENLNKLMTNLKTTHPHFVRCL 673
Query: 2035 IPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK- 2211
IPN K G +++ LV+ QLRCNGVLEGIRICR+GFPNR+ + +F+ R IL IP+
Sbjct: 674 IPNESKIPGIMDNCLVMHQLRCNGVLEGIRICRKGFPNRILYGDFKQRCRILNASAIPEG 733
Query: 2212 NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCR 2391
FI+ K+S K++ +LDID Y+ G +KVFF+ G+L LEE RD +L ++ QA R
Sbjct: 734 QFIENKKSAEKLLGSLDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDQLARILTGIQAFAR 793
Query: 2392 GFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKD 2571
G L R Y N ++L ++NW W +LF K+KPLL+ ++ E+
Sbjct: 794 GLLMRVEYQKLVERRDALMVVQWNLRSFLGVKNWPWMKLFFKIKPLLKSAESEKEMANMK 853
Query: 2572 DELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQ 2751
DE KE L K + +E E+K+ ++ E+ + Q+Q E + + ++ +L
Sbjct: 854 DEFNKLKEALEKSDARRKELEEKMVSLLQEKNDLLLQVQSEQDTLTDAEERCEQLIKSKI 913
Query: 2752 ELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQ 2931
+LE V ++ +R+ RRK + + +K +
Sbjct: 914 QLEAKVKELSERIEDEEEINADLTAKRRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 973
Query: 2932 XXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHE 3111
+ L E++ KAK +LE Q+ +
Sbjct: 974 KVKNITEEMASLDENIMKLTKEKKALQEAHQQTLDDLQSEEDKVNTLTKAKVKLEQQVDD 1033
Query: 3112 LEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTR 3291
LE L +E++ + +LE+ KRKL +++ +++++ + ++L ++L K+D E+ R
Sbjct: 1034 LEGSLEQEKKVRMDLERSKRKLEGDVKLTQENVMDLENDKQQLEDKLKKKDFEINQLNQR 1093
Query: 3292 YDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDK 3471
++E +QK++++ Q I+EL E+++ ER AR K E R ++ +LE + + L++
Sbjct: 1094 IEDEQMASVQLQKKLKENQARIEELEEELDAERAARAKVEKQRSDISRELEDI-SERLEE 1152
Query: 3472 VDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKK 3648
AT Q +L ++D E +R +E+ E + K + V EL +QI+ ++
Sbjct: 1153 AGGATSAQVELNKKRDAEFQKIRRDLEESTLQHEATTASLRKKHADSVAELGEQIDNLQR 1212
Query: 3649 QRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRT 3828
+ +LEK++ + E D+A + + ++ +++K + E + E ++ E+
Sbjct: 1213 VKQKLEKEKVELKLELDDLASNMESIVKAKVNLEKMCRSLEDQMNEHRSKAEEAQRALND 1272
Query: 3829 LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINR 4008
+ Q + E L R EE+E + + R + + K A +
Sbjct: 1273 VSTQKAKLLTENGELGRQLEEKECLISQLTRGKTSYAQQLEDLRRQLEEEVKAKNALAHA 1332
Query: 4009 ARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEEL---RKK 4179
+ + + L ++ EE + +A L++ + A R + E Q+ EEL +KK
Sbjct: 1333 VQSARHDCDLLREQFEEEQEAKAELQRALSKANTEVATWRARYETDGIQRTEELEDAKKK 1392
Query: 4180 NLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQ 4359
++ ++ ++ +E + ++K ++Q E+ED ++LE A+ +K+Q+ F+
Sbjct: 1393 LVQKLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMLDLERSNAASAALDKKQRSFDKV 1452
Query: 4360 MAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDS 4539
MAE + +++ + + +E R T + L N + +HLE R ++LQ+E+ D
Sbjct: 1453 MAEWKQKYEESQCELEGAQKEARSLSTELFKLKNSYEETLDHLETIKRENKNLQEEISDL 1512
Query: 4540 ISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSES 4719
+ K+VHELEK ++ LE E +++ +EE + +++ E LR ++ LK++
Sbjct: 1513 TDQVSEGRKSVHELEKLRKQLEQEKTELQSALEEADASVEHEEGKILRAQLEFNQLKADF 1572
Query: 4720 DRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
+R +S KD E E+ RR + I L+ LE E R ++ A+ +KK+E + E+E QL A
Sbjct: 1573 ERKMSEKDEEMEQARRNYQRMIESLQASLEAETRSRNEALRVKKKMEGDLNEMEIQLSQA 1632
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREAN 5079
NR + E Q++ ++ + +D+ + +R+ ++ E E+LR
Sbjct: 1633 NRQAADAQKQLKMVQSCLKETQLQMDDTLHSNDDLKENITLLERRNNLMQTELEELRGIL 1692
Query: 5080 EGLMQARK----QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELA 5247
E + RK + ++ G+ +++K++ E+ + Q A
Sbjct: 1693 EQTERVRKLAEQELTDATERMQLLHSQNTGLINQKKKQ-ESDLLQLQNELEELVQENRNA 1751
Query: 5248 IDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQ 5427
+K +KA + +L E+ + E K+++E++ +D + ++ E E A + Q
Sbjct: 1752 EEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQVAMKGGKKQ 1811
Query: 5428 MAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKS 5607
+ +EA+++ LE++L+ E + + + + R+ E+R+ + T Q +++++ + ++L++K
Sbjct: 1812 LQKMEARIRELENELDAEQKRGSESVKGVRKFERRIKELTYQTDEDRKNLARLQDLVDKL 1871
Query: 5608 NLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
LK ++ +R +EAE+ + K R +Q E ++
Sbjct: 1872 QLKVKSYKRSAEEAEELANANTAKLRKLQHELEE 1905
Score = 138 bits (347), Expect = 2e-30
Identities = 169/795 (21%), Positives = 328/795 (41%), Gaps = 49/795 (6%)
Frame = +1
Query: 3502 MSRKDEEVNATKRAIE-------QIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQ 3660
M+ +E N K A+E +++ M ++E K QV+ D + +++ Q
Sbjct: 849 MANMKDEFNKLKEALEKSDARRKELEEKMVSLLQE-KNDLLLQVQSEQDTLTDAEERCEQ 907
Query: 3661 LEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME-------IQANLAESDEH 3819
L K + Q + + ++++ I + AD+ KR+ E E ++ LA+ ++
Sbjct: 908 LIKSKIQLEAKVKELSERIEDEEEINADLTAKRRKLEDECSELKKDIDDLELTLAKVEKE 967
Query: 3820 KRTLIDQLERSRDEL----DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL 3987
K ++++ +E+ +++ ++ +E++ Q+ L +L
Sbjct: 968 KHATENKVKNITEEMASLDENIMKLTKEKKALQEAHQQTLDDLQSEEDKVNTLTKAKVKL 1027
Query: 3988 KIANINRARQLEDEKNALLD---EKEEAEG---LRAHLEKEIHAARQGAGEARRKAEESV 4149
+ + LE EK +D K + EG L ++ +Q + +K + +
Sbjct: 1028 EQQVDDLEGSLEQEKKVRMDLERSKRKLEGDVKLTQENVMDLENDKQQLEDKLKKKDFEI 1087
Query: 4150 NQ-------------QLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSS 4290
NQ QL++ K+N +E L+++L+ A+ ++ + + I +ELED S
Sbjct: 1088 NQLNQRIEDEQMASVQLQKKLKENQARIEELEEELDAERAARAKVEKQRSDISRELEDIS 1147
Query: 4291 MELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRET-RVLSLLNEV 4467
LE + + KK +++ + R ++++ L +A + LR + V L ++
Sbjct: 1148 ERLEEAGGATSAQVELNKKRDAEFQKIRRDLEESTLQHEATTASLRKKHADSVAELGEQI 1207
Query: 4468 DIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELE 4647
D ++ ++ ++ + L+ EL D SN + K LEK RSLE ++N+ R + EE +
Sbjct: 1208 DNLQRVKQKLEKEKVELKLELDDLASNMESIVKAKVNLEKMCRSLEDQMNEHRSKAEEAQ 1267
Query: 4648 DNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRG---LLKQIRDLENELENEK 4818
L + +L N E R + K+ + RG +Q+ DL +LE E
Sbjct: 1268 RALNDVSTQKAKLLTEN----GELGRQLEEKECLISQLTRGKTSYAQQLEDLRRQLEEEV 1323
Query: 4819 RGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQI--------EC 4974
+ K+ + + L +Q E K E ++
Sbjct: 1324 KAKNALAHAVQSARHDCDLLREQFEEEQEAKAELQRALSKANTEVATWRARYETDGIQRT 1383
Query: 4975 EEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGG 5154
EE AK+ + L++A+ AV A+ L + R Q R+
Sbjct: 1384 EELEDAKKKLVQKLQDAEEAVEAVNAKCSSLEKTKH-----RLQNEIEDLMLDLERSNAA 1438
Query: 5155 GISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTE 5334
+ ++K+R K+ +S CEL AQ + ++T+L + ++T
Sbjct: 1439 SAALDKKQRSFDKV-MAEWKQKYEESQCEL-----EGAQKEARSLSTELFKLKNSYEETL 1492
Query: 5335 AEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAA 5514
++++R N++ + +I++L + S R + LE + LE QEKT A
Sbjct: 1493 DHLETIKRENKNLQEEISDL-TDQVSEGRKSVHELEKLRKQLE-------QEKTELQSAL 1544
Query: 5515 RRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQ 5694
D + + E+ K Q LE + LK + R++ E ++EM + R RN Q
Sbjct: 1545 EEA-----DASVEHEEGKILRAQ----LEFNQLK-ADFERKMSEKDEEMEQAR---RNYQ 1591
Query: 5695 READDLLDANEQLTR 5739
R + L + E TR
Sbjct: 1592 RMIESLQASLEAETR 1606
Score = 110 bits (274), Expect = 5e-22
Identities = 175/886 (19%), Positives = 345/886 (38%), Gaps = 120/886 (13%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKL----------DQVIVERAVIQEQLQQE-SENS 2706
R + +++ T+E ++ +E+D ++ E KL +Q I + + QLQ++ EN
Sbjct: 1053 RKLEGDVKLTQENVMDLENDKQQLEDKLKKKDFEINQLNQRIEDEQMASVQLQKKLKENQ 1112
Query: 2707 AELDDI----------RGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVR 2856
A ++++ R +++ + ++ + D+ +RL +K R
Sbjct: 1113 ARIEELEEELDAERAARAKVEKQRSDISRELEDISERLEEAGGATSAQVELNKK-----R 1167
Query: 2857 DXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTT 3036
D + T + D L
Sbjct: 1168 DAEFQKIRRDLEESTLQHEATTASLRKKHADSVAELGEQI-DNLQRVKQKLEKEKVELKL 1226
Query: 3037 QLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQ-------HKRKLLAELED 3195
+L D + VKAK LE LE +N R E ++ K KLL E +
Sbjct: 1227 ELDDLASNMESIVKAKVNLEKMCRSLEDQMNEHRSKAEEAQRALNDVSTQKAKLLTENGE 1286
Query: 3196 SKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELRED 3375
L EK + +L ++L+ + +EE + ++ + D LRE
Sbjct: 1287 LGRQLEEKECLISQLTRGKTSYAQQLEDLRRQLEEEVKAKNALAHAVQSARHDCDLLREQ 1346
Query: 3376 METERNARNKAEMTRR------EVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATK 3537
E E+ A KAE+ R EV + + D + + +E L+D + +++ +
Sbjct: 1347 FEEEQEA--KAELQRALSKANTEVATWRARYETDGIQRTEE---LEDAKKKLVQKLQDAE 1401
Query: 3538 RAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEI 3717
A+E + +E+ K + ++E+L +E+ + L+K+Q D+ A+ Q+
Sbjct: 1402 EAVEAVNAKCSS-LEKTKHRLQNEIEDLMLDLERSNAASAALDKKQRSFDKVMAEWKQKY 1460
Query: 3718 ALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRT--------------LIDQLERSR 3855
Q K+ + L +++ + E+ +H T L DQ+ R
Sbjct: 1461 EESQCELEGAQKEARSLSTELFKLKNSYEETLDHLETIKRENKNLQEEISDLTDQVSEGR 1520
Query: 3856 DELDHLNRVREEEEHAFANMQRRL----ATAXXXXXXXXXXXXXXTRLKIANINRARQLE 4023
+ L ++R++ E +Q L A+ +LK A+ R +
Sbjct: 1521 KSVHELEKLRKQLEQEKTELQSALEEADASVEHEEGKILRAQLEFNQLK-ADFERKMSEK 1579
Query: 4024 DEK--NALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVE 4197
DE+ A + + E L+A LE E + R A ++K E +N+ +L + N R
Sbjct: 1580 DEEMEQARRNYQRMIESLQASLEAETRS-RNEALRVKKKMEGDLNEMEIQLSQAN-RQAA 1637
Query: 4198 HLQKQLE-------ESEVAKERILQSKKKIQQ-----ELEDSSM--ELENVRASHRDSEK 4335
QKQL+ E+++ + L S +++ E ++ M ELE +R +E+
Sbjct: 1638 DAQKQLKMVQSCLKETQLQMDDTLHSNDDLKENITLLERRNNLMQTELEELRGILEQTER 1697
Query: 4336 RQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVD-IMKEHLEESDRVRR 4512
+K E ++ + +Q + + + +E+ +L L NE++ +++E+ ++ ++
Sbjct: 1698 VRKLAEQELTDATERMQLLHSQNTGLINQKKKQESDLLQLQNELEELVQENRNAEEKAKK 1757
Query: 4513 SLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELED--------NLQIAE 4668
++ + K + + H LE+ K+++E + D++ +++E E LQ E
Sbjct: 1758 AITDAAMMAEELKKEQDTSAH-LERMKKNMEQTIKDLQHRLDEAEQVAMKGGKKQLQKME 1816
Query: 4669 DARLRLEVTN-----QALKSES-------DRAISNKDVEAEEKRRGLLK----------- 4779
AR+R E+ N Q SES +R I + +E R+ L +
Sbjct: 1817 -ARIR-ELENELDAEQKRGSESVKGVRKFERRIKELTYQTDEDRKNLARLQDLVDKLQLK 1874
Query: 4780 --------------------QIRDLENELENEKRGKSGAVSHRKKI 4857
++R L++ELE + A S K+
Sbjct: 1875 VKSYKRSAEEAEELANANTAKLRKLQHELEEAEERADIAESQVNKL 1920
Score = 93.6 bits (231), Expect = 5e-17
Identities = 89/454 (19%), Positives = 192/454 (41%), Gaps = 36/454 (7%)
Frame = +1
Query: 3037 QLLDHEERAKHGVKAKGR----LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKD 3204
+ LDH E K K L +Q+ E + ++ + + +LEQ K +L + LE++
Sbjct: 1490 ETLDHLETIKRENKNLQEEISDLTDQVSEGRKSVHELEKLRKQLEQEKTELQSALEEADA 1549
Query: 3205 HLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMET 3384
+ + GK+ + + + + +++ DEE M++ R+ Q I+ L+ +E
Sbjct: 1550 SVEHEEGKILRAQLEFNQLKADFERKMSEKDEE------MEQARRNYQRMIESLQASLEA 1603
Query: 3385 ERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHT 3564
E +RN+A ++++ L +++ + +A Q + + T+ ++ H+
Sbjct: 1604 ETRSRNEALRVKKKMEGDLNEMEIQLSQANRQAADAQKQLKMVQSCLKETQLQMDDTLHS 1663
Query: 3565 MEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRAD 3744
+ ++E R+ + ++E+ + Q E+ + A+QE D + + LL +
Sbjct: 1664 NDD-LKENITLLERRNNLMQTELEELRGILEQTERVRKLAEQELTDATERMQLLHSQNTG 1722
Query: 3745 IDKKRKIHEAHLMEIQANLAESDEHKRT--------------LIDQLERSRDELDHLNRV 3882
+ ++K E+ L+++Q L E + R + ++L++ +D HL R+
Sbjct: 1723 LINQKKKQESDLLQLQNELEELVQENRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERM 1782
Query: 3883 REEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEA 4062
++ E ++Q RL A +I R+LE+E +A ++K +
Sbjct: 1783 KKNMEQTIKDLQHRLDEAEQVAMKGGKKQLQKMEARI------RELENELDA--EQKRGS 1834
Query: 4063 EGLRA--HLEKEIHAARQGAGEARR----------------KAEESVNQQLEELRKKNLR 4188
E ++ E+ I E R+ K+ + ++ EEL N
Sbjct: 1835 ESVKGVRKFERRIKELTYQTDEDRKNLARLQDLVDKLQLKVKSYKRSAEEAEELANANTA 1894
Query: 4189 DVEHLQKQLEESEVAKERILQSKKKIQQELEDSS 4290
+ LQ +LEE+E + K++ + D +
Sbjct: 1895 KLRKLQHELEEAEERADIAESQVNKLRAKTRDGA 1928
Score = 74.3 bits (181), Expect = 3e-11
Identities = 97/453 (21%), Positives = 197/453 (43%), Gaps = 18/453 (3%)
Frame = +1
Query: 4429 DRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEA 4608
+ E + ++ +E + +KE LE+SD R+ ELE+ SL
Sbjct: 844 ESEKEMANMKDEFNKLKEALEKSDARRK---------------------ELEEKMVSLLQ 882
Query: 4609 ELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIR 4788
E ND+ +Q++ +D L AE E Q +KS+ ++ E K ++
Sbjct: 883 EKNDLLLQVQSEQDTLTDAE------ERCEQLIKSK---------IQLEAK-------VK 920
Query: 4789 DLENELENEKRGKSGAVSHRKKIENQIGELEQ-----QLEVANRLKEEYXXXXXXXXXXX 4953
+L +E+E+ + + R+K+E++ EL++ +L +A KE++
Sbjct: 921 ELSERIEDEEEINADLTAKRRKLEDECSELKKDIDDLELTLAKVEKEKHATE-------- 972
Query: 4954 XEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXX 5133
+ + E++A+L D + E++ L+EA++ + +
Sbjct: 973 -------NKVKNITEEMASL----DENIMKLTKEKKALQEAHQQTLDDLQSEEDKVNTLT 1021
Query: 5134 XXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMER 5313
+ K LE ++ + E ++++++K ++ LE+ L +
Sbjct: 1022 KAKVK-----------LEQQV-----------DDLEGSLEQEKKVRMDLERSKRKLEGDV 1059
Query: 5314 TLNQKT----EAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVE 5481
L Q+ E +KQ LE + +I +L + QMA+++ + + E+Q +E
Sbjct: 1060 KLTQENVMDLENDKQQLEDKLKKKDFEINQLNQRIEDE---QMASVQLQKKLKENQARIE 1116
Query: 5482 G-QEKTAANRAAR-RLEKRLNDTTQQFEDEKRANEQA-------KELLEKSNLKNRNLRR 5634
+E+ A RAAR ++EK+ +D +++ ED E+A EL +K + + + +RR
Sbjct: 1117 ELEEELDAERAARAKVEKQRSDISRELEDISERLEEAGGATSAQVELNKKRDAEFQKIRR 1176
Query: 5635 QLDEAEDEMSRERTKHRNVQREADDLLDANEQL 5733
L+E+ + E T ++ AD + + EQ+
Sbjct: 1177 DLEES--TLQHEATTASLRKKHADSVAELGEQI 1207
Score = 47.8 bits (112), Expect = 0.003
Identities = 46/241 (19%), Positives = 106/241 (43%)
Frame = +1
Query: 5020 EADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIA 5199
E++++ ++ E +L+EA E RK+ +EK L ++
Sbjct: 844 ESEKEMANMKDEFNKLKEALEKSDARRKELEEKMVSLL-----------QEKNDLLLQVQ 892
Query: 5200 QXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKA 5379
+ CE I + + + ++++++ + E +N A+++ LE + K
Sbjct: 893 SEQDTLTDAEERCEQLIKSKIQLEAKVKELSERIEDEEEINADLTAKRRKLEDECSELKK 952
Query: 5380 KITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFE 5559
I +LE ++ + A E KV+ + +++ + + +K L + QQ
Sbjct: 953 DIDDLEL-TLAKVEKEKHATENKVKNITEEMASLDENIMKLTKE----KKALQEAHQQTL 1007
Query: 5560 DEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTR 5739
D+ ++ E L K+ +K L +Q+D+ E + +E+ +++R + L+ + +LT+
Sbjct: 1008 DDLQSEEDKVNTLTKAKVK---LEQQVDDLEGSLEQEKKVRMDLER-SKRKLEGDVKLTQ 1063
Query: 5740 E 5742
E
Sbjct: 1064 E 1064
>gi|48103366|ref|XP_395558.1| similar to CG15792-PA [Apis mellifera]
Length = 1453
Score = 1092 bits (2824), Expect = 0.0
Identities = 639/1533 (41%), Positives = 898/1533 (57%), Gaps = 14/1533 (0%)
Frame = +1
Query: 1195 LQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQG 1374
+ KAFL+PRIKVGR+FV KAQ +EQ EFAVEAI+KA YER+F+WLV RIN+SLDRT RQG
Sbjct: 1 MTKAFLKPRIKVGRDFVTKAQTKEQVEFAVEAISKACYERMFRWLVNRINRSLDRTKRQG 60
Query: 1375 ASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDF 1554
ASFIGILD+AGFEIF++NSFEQ+CINYTNEKLQQLFN+TMFILEQEEYQREGIEW FIDF
Sbjct: 61 ASFIGILDMAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWKFIDF 120
Query: 1555 GLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTHNKHPKFIVPDMRSKSHF 1734
GLDLQPTIDLI+KPMG++ALLDEEC FPKA DK+FVEKL H+ HPKF+ D R + F
Sbjct: 121 GLDLQPTIDLIDKPMGIMALLDEECWFPKATDKTFVEKLVGAHSVHPKFMKTDFRGVADF 180
Query: 1735 AVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNET 1914
A++HYAG+VDYSA +WLMKNMDPLNENVV L+QNS DPFV IWKDAE G+ + +T
Sbjct: 181 AIIHYAGKVDYSAAKWLMKNMDPLNENVVSLLQNSQDPFVCHIWKDAEIVGMAQQALTDT 240
Query: 1915 AFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQL 2094
FG R+RKGMFRTVSQL+KEQL KLM TLRNT+P+FVRCIIPNHEKK+GKI++ LVL+QL
Sbjct: 241 QFGARTRKGMFRTVSQLYKEQLAKLMITLRNTNPNFVRCIIPNHEKKAGKIDAPLVLDQL 300
Query: 2095 RCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTN 2274
RCNGVLEGIRICRQGFPNR+PFQEFR RYE+LTP+ IPK F+DGK++ KMI AL++D N
Sbjct: 301 RCNGVLEGIRICRQGFPNRIPFQEFRQRYELLTPNAIPKGFMDGKKACEKMIQALELDPN 360
Query: 2275 LYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXX 2454
LYR+GQSK+FFR GVLAHLEEE +LK + Q R+ Y
Sbjct: 361 LYRVGQSKIFFRAGVLAHLEEEHELKQVRDKLELQLHSAQEYERK-YQQAMEEKTMLAEQ 419
Query: 2455 XXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRAT-----KERL----LK 2607
+ RL + + L ++ D E R +++E R+ K++L
Sbjct: 420 LQAEVELCAEAEEMRARLAARKQELEEILH-DLETRIEEEEERSAGLAQEKKKLQLNISD 478
Query: 2608 MEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDR 2787
+E E E ++ +E+ ++++ E+ A DD +L + LE ND+
Sbjct: 479 LEEQLEEEEAARQKLQLEKVQCDAKIKKLEEDLALSDDTNQKLLKEKKILEERANDLSQT 538
Query: 2788 LSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXX 2967
L+ + K T+ D K ++
Sbjct: 539 LAEEEEKAKHLSKLKAKHEATIADLEERLLKDHQQRQEVDRSKRKIETEVSDLKEQLAER 598
Query: 2968 QDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAK-HGVKAKGRLENQLHELEQDLNRERQY 3144
+ + + + +D E AK KA LE+QL EL++DL E+
Sbjct: 599 KTQVEEFQLQLGKREEELNQIMAK-MDEEGAAKAQAQKALRELESQLAELQEDLEAEKIA 657
Query: 3145 KSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLM 3324
+ + E+ KR L ELE K+ L + + KR++EL +EE++
Sbjct: 658 RGKAEKLKRDLNEELEALKNELLDSLDTTAAQQELRSKREQELATLKKNLEEETS----- 712
Query: 3325 QKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDV-LDKVDEATMLQDL 3501
+ T+ ++R E A N+ ++ LEK K + + D AT L+ +
Sbjct: 713 -----IHEATLADMRHKHTQELTALNEQMDALKKTKTVLEKAKATLEAENADLATELRSV 767
Query: 3502 MSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQ 3681
+ + E K+A +Q+ E++ ++ + ++ R +L ++ +
Sbjct: 768 SASRQESDRRRKQA-------------------EQQLAEINAKLAEVERNRQELVERVTK 808
Query: 3682 ADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDE 3861
QE + Q++ + + K E+ E+Q L E K L +L E
Sbjct: 809 LQQESESIMQQLEAAELKASAALKASATCESQFTELQQQLEEETRQKLALSSKLRALESE 868
Query: 3862 LDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNAL 4041
+ L+ EEEE A R L+ + L
Sbjct: 869 KESLHDQLEEEEEA-----------------------------------KRALDKQVLGL 893
Query: 4042 LDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEE 4221
+ EA+ RA E E AA + A + K E++ +Q+EEL
Sbjct: 894 NVQLAEAK-KRAEEEAEAAAALEEARKRCMKDIEALQRQVEEL----------------- 935
Query: 4222 SEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLD 4401
+ A +++ +SKKKIQ E+EDS +ELE RA + EK+QK F+ +AEE+ ++
Sbjct: 936 -QAANDKLDKSKKKIQAEVEDSIIELEAQRAKVLELEKKQKNFDKVLAEEKAVSEQYAEQ 994
Query: 4402 RDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHEL 4581
RDA +E R++ETRVLSL E+D M E +EE +R+RR LQ EL + ++N+ KNVHEL
Sbjct: 995 RDAAEREAREKETRVLSLTRELDEMNEKVEELERIRRGLQSELDELVNNQGTADKNVHEL 1054
Query: 4582 EKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEK 4761
EKAKR+LE++L + R Q+EELED LQ EDA+LRLEV QAL+++ +R + K+ +AEEK
Sbjct: 1055 EKAKRALESQLAEQRSQVEELEDELQFTEDAKLRLEVNMQALRAQFERDLQAKEEQAEEK 1114
Query: 4762 RRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXX 4941
RRGL+KQ+RDLE ELE+E++ K+ A++ RKK+E ++EQQLE+ N++KE+
Sbjct: 1115 RRGLVKQLRDLEAELEDERKQKAAAIAQRKKMEADYKDIEQQLEMHNKVKEDALKQLKKL 1174
Query: 4942 XXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLRE---ANEGLMQARKQXX 5112
+ E EEAR A++++AA +E ++K +++EA+ QL E ++E +A +
Sbjct: 1175 QAQIKDCTRETEEARAARDELAASAKETEKKVKSLEADLMQLTEDFASSERARRAAENER 1234
Query: 5113 XXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQIT 5292
A G + +EKRRLEA+IA QSN EL +D+ RKAQ+ +EQ+T
Sbjct: 1235 DELQEELNNNANKGTLMLDEKRRLEARIATLEEELEEEQSNAELLMDRARKAQITIEQLT 1294
Query: 5293 TDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQL 5472
DL+ ER+ QK E+ K LER N++ KAK+TELE+ +++ +A + LE+K+ L++QL
Sbjct: 1295 NDLTTERSTTQKLESHKLLLERQNKELKAKLTELETAQRAKTKATIQQLESKINNLDEQL 1354
Query: 5473 NVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAE 5652
E +E+ A + R+LEK+L + + Q EDE+R ++Q KE EK N + + L+RQLDEAE
Sbjct: 1355 ETEAKERFAQQKINRKLEKKLKELSLQLEDERRNSDQYKEQAEKVNARMKALKRQLDEAE 1414
Query: 5653 DEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
+E+SR + R QRE DD+L++ E+LTRE+ N
Sbjct: 1415 EEISRHKAMKRKAQREMDDMLESQEELTREVAN 1447
Score = 105 bits (263), Expect = 1e-20
Identities = 126/576 (21%), Positives = 224/576 (38%), Gaps = 88/576 (15%)
Frame = +1
Query: 3025 GLTTQLLDHEERAKHGVKAKGRLEN-------QLHELEQDLNRERQYKSELEQHKRKLLA 3183
GL QL + ++RA+ +A LE + L++ + + +L++ K+K+ A
Sbjct: 892 GLNVQLAEAKKRAEEEAEAAAALEEARKRCMKDIEALQRQVEELQAANDKLDKSKKKIQA 951
Query: 3184 ELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQ--------------------------- 3282
E+EDS L + KV EL + D+ L +
Sbjct: 952 EVEDSIIELEAQRAKVLELEKKQKNFDKVLAEEKAVSEQYAEQRDAAEREAREKETRVLS 1011
Query: 3283 LTR-YDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGD 3459
LTR DE + V +++ R +Q+ +DEL + T ++ E +R + +QL + +
Sbjct: 1012 LTRELDEMNEKVEELERIRRGLQSELDELVNNQGTADKNVHELEKAKRALESQLAEQRSQ 1071
Query: 3460 VLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQ 3639
V + DE +D R + + A + E+ E + EE++ +Q+ +L ++E
Sbjct: 1072 VEELEDELQFTEDAKLRLEVNMQALRAQFERDLQAKEEQAEEKRRGLVKQLRDLEAELED 1131
Query: 3640 HKKQRSQLEKQQNQADQERADMAQEIAL-------------------------------- 3723
+KQ++ Q+ + + + D+ Q++ +
Sbjct: 1132 ERKQKAAAIAQRKKMEADYKDIEQQLEMHNKVKEDALKQLKKLQAQIKDCTRETEEARAA 1191
Query: 3724 ---LQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEE 3894
L AS + +KK K EA LM++ + A S+ +R E RDEL +
Sbjct: 1192 RDELAASAKETEKKVKSLEADLMQLTEDFASSERARRAA----ENERDELQEELNNNANK 1247
Query: 3895 EHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRAR-QLEDEKNALLDEKEEAEGL 4071
+ +RRL L + +A+ +E N L E+ + L
Sbjct: 1248 GTLMLDEKRRLEARIATLEEELEEEQSNAELLMDRARKAQITIEQLTNDLTTERSTTQKL 1307
Query: 4072 RAHL------EKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVA 4233
+H KE+ A A+R ++ QQLE + +L +QLE A
Sbjct: 1308 ESHKLLLERQNKELKAKLTELETAQRAKTKATIQQLES-------KINNLDEQLETE--A 1358
Query: 4234 KERILQSK---------KKIQQELEDSSMELENVRASHRDSEKRQKKFESQM--AEERVA 4380
KER Q K K++ +LED + + R K + Q+ AEE ++
Sbjct: 1359 KERFAQQKINRKLEKKLKELSLQLEDERRNSDQYKEQAEKVNARMKALKRQLDEAEEEIS 1418
Query: 4381 VQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHL 4488
KA+ + +E+ D L EV +K L
Sbjct: 1419 RHKAM--KRKAQREMDDMLESQEELTREVANLKNKL 1452
Score = 67.4 bits (163), Expect = 4e-09
Identities = 73/415 (17%), Positives = 169/415 (40%), Gaps = 16/415 (3%)
Frame = +1
Query: 2533 QVTRTDDEIRAKDDELRATKERLLKMEHDF--------RENEKKLDQVIVERAVIQEQLQ 2688
Q+ ++ +DEL+ T++ L++E + R+ + K +Q +R + +QL+
Sbjct: 1064 QLAEQRSQVEELEDELQFTEDAKLRLEVNMQALRAQFERDLQAKEEQAEEKRRGLVKQLR 1123
Query: 2689 QESENSAELDDIRGR-----LQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETV 2853
+ AEL+D R + Q + E +Y D+ +L +K +
Sbjct: 1124 ---DLEAELEDERKQKAAAIAQRKKMEADY--KDIEQQLEMHNKVKEDALKQLKKLQAQI 1178
Query: 2854 RDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLT 3033
+D ++ + + L
Sbjct: 1179 KDCTRETEEARAARDELAASAKETEKKVKSLEADLMQLTEDFASSERARRAAENERDELQ 1238
Query: 3034 TQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLA 3213
+L ++ + + K RLE ++ LE++L E+ L RK +E + L
Sbjct: 1239 EELNNNANKGTLMLDEKRRLEARIATLEEELEEEQSNAELLMDRARKAQITIEQLTNDLT 1298
Query: 3214 EKMGKVEELNNQ---LMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMET 3384
+ ++L + L ++++EL+ +LT E+A + ++ +++ I+ L E +ET
Sbjct: 1299 TERSTTQKLESHKLLLERQNKELKAKLTEL--ETAQRAKTKATIQQLESKINNLDEQLET 1356
Query: 3385 ERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHT 3564
E R ++++ +LEK ++ ++++ D + E+VNA +A++
Sbjct: 1357 EAKER----FAQQKINRKLEKKLKELSLQLEDERRNSDQYKEQAEKVNARMKALK----- 1407
Query: 3565 MEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQ 3729
RQ++E ++I +HK + + +++ + + + ++ +E+A L+
Sbjct: 1408 -------------RQLDEAEEEISRHKAMKRKAQREMDDMLESQEELTREVANLK 1449
>gi|39645256|gb|AAH18933.2| MYH14 protein [Homo sapiens]
Length = 931
Score = 1091 bits (2821), Expect = 0.0
Identities = 546/897 (60%), Positives = 691/897 (76%), Gaps = 8/897 (0%)
Frame = +1
Query: 124 SIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDR 303
+++ E +E VEL ++ R++ + RD +Q+ NPPKF K EDM+ELT LNEASVLHNL++R
Sbjct: 2 ALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRER 61
Query: 304 YYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQE 483
YYS LIYTYSGLFCVVINPYK+LPIY+E ++E ++GKKRHE+PPH++A+ + AYRSMLQ+
Sbjct: 62 YYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQD 121
Query: 484 REDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGEL 663
REDQSILCTGESGAGKTENTKKVIQYLAHVA + + + ++P V GEL
Sbjct: 122 REDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGR-----------KEPGVP---GEL 167
Query: 664 EHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQ 843
E QLLQANPILEAFGN+KTVKNDNSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQ
Sbjct: 168 ERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQ 227
Query: 844 AQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMR 1023
A+DE SFHIFYQ+L G + K++ LLE +YRFL N + P + + F T+ S+R
Sbjct: 228 AKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPG-QERELFQETLESLR 286
Query: 1024 IMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQK 1203
++GF+ +EI S++R+VSAVL GN+ +E+ +DQA + D+ QK+C LLGL V + +
Sbjct: 287 VLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSR 346
Query: 1204 AFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASF 1383
A L PRIKVGR++V KAQ +EQA+FA+EA+AKA+YERLF+WLV R+N++LDR+ RQGASF
Sbjct: 347 ALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASF 406
Query: 1384 IGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLD 1563
+GILDIAGFEIF +NSFEQ+CINYTNEKLQQLFN+TMF+LEQEEYQREGI W F+DFGLD
Sbjct: 407 LGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLD 466
Query: 1564 LQPTIDLIEKPM---GVLALLDEECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSH 1731
LQP IDLIE+P G+LALLDEEC FPKA DKSFVEK+ + HPKF P +R ++
Sbjct: 467 LQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQAD 526
Query: 1732 FAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAE--- 1902
F+V+HYAG+VDY A++WLMKNMDPLN+NV L+ STD A IWKD E GI E
Sbjct: 527 FSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVE--GIVGLEQVS 584
Query: 1903 -MNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNL 2079
+ + G R R+GMFRTV QL+KE L++LM TL NT+P FVRCI+PNHEK++GK+ L
Sbjct: 585 SLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRL 644
Query: 2080 VLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITAL 2259
VL+QLRCNGVLEGIRICRQGFPNR+ FQEFR RYEILTP+ IPK F+DGK++ KMI AL
Sbjct: 645 VLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQAL 704
Query: 2260 DIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXX 2439
++D NLYR+GQSK+FFR GVLA LEEERDLK+T +I++FQA RG+L+RR +
Sbjct: 705 ELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQS 764
Query: 2440 XXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHD 2619
N AYLKLR+WQWWRLFTKVKPLLQVTR D+ ++A+ EL+ +E + +
Sbjct: 765 ALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSARE 824
Query: 2620 FRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRL 2790
E + ++ Q+ ERA + EQL+ E+E AE ++ RGRL R QELE +V+++ R+
Sbjct: 825 VGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARV 881
Score = 37.7 bits (86), Expect = 3.4
Identities = 35/160 (21%), Positives = 71/160 (43%), Gaps = 2/160 (1%)
Frame = +1
Query: 3211 AEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETER 3390
A+++ KV+EL Q + ELQ ++ + +EE A L E + E
Sbjct: 808 AQELQKVQELQQQSAREVGELQGRVAQLEEERA-----------------RLAEQLRAEA 850
Query: 3391 NARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTME 3570
+AE TR + A+ ++++ ++ +L +R EE ++
Sbjct: 851 ELCAEAEETRGRLAARKQELE----------LVVSELEARVGEEEECSR----------- 889
Query: 3571 GKIEEQKAKFSRQVEEL--HDQIEQHKKQRSQLEKQQNQA 3684
+++ +K + + ++EL H + E+ +Q+ QLEK +A
Sbjct: 890 -QMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEA 928
>gi|17509401|ref|NP_493596.1| UNCoordinated locomotion UNC-54, encodes
major bodywall muscle myosin heavy chain MHC B (MYO-4),
MYOsin heavy chain structural gene (224.8 kD) (unc-54)
[Caenorhabditis elegans]
gi|11384450|pir||MWKW myosin heavy chain B [similarity] -
Caenorhabditis elegans
gi|3875751|emb|CAB04089.1| Hypothetical protein F11C3.3
[Caenorhabditis elegans]
gi|3876585|emb|CAB05505.1| C. elegans UNC-54 protein (corresponding
sequence F11C3.3) [Caenorhabditis elegans]
Length = 1963
Score = 1090 bits (2819), Expect = 0.0
Identities = 650/1936 (33%), Positives = 1052/1936 (53%), Gaps = 25/1936 (1%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
QYL+ R V + + + +K W+PD EG+L G I D+V + + +VT+
Sbjct: 10 QYLRRTREQVLEDQS-KPYDSKKNVWIPDPEEGYLAGEITATKGDQVTI-VTARGNEVTL 67
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++ VQ+ NPPKF+K EDMS L++LN+ASVLHNL+ RY + LIYTYSGLFCVVINPYK+L
Sbjct: 68 KKELVQEMNPPKFEKTEDMSNLSFLNDASVLHNLRSRYAAMLIYTYSGLFCVVINPYKRL 127
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIY++ F GK++ EMPPH+FA++D AYR+MLQ+ E+QS+L TGESGAGKTENTKKV
Sbjct: 128 PIYTDSCARMFMGKRKTEMPPHLFAVSDEAYRNMLQDHENQSMLITGESGAGKTENTKKV 187
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
I Y A V A+QQ + D LE Q++Q NP+LEAFGN+KTV+N+
Sbjct: 188 ICYFAAVG----------ASQQEGGAEVDPNKKKVTLEDQIVQTNPVLEAFGNAKTVRNN 237
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRI+F+ G ++ +IE YLLEKSRV+RQA ER +HIFYQI + K
Sbjct: 238 NSSRFGKFIRIHFNKHGRLASCDIEHYLLEKSRVIRQAPGERCYHIFYQIYSDFRPELKK 297
Query: 913 EYLLE-GVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLL 1089
E LL+ + +Y F+ + + +DDV+EF T + I+ F+ E R++SA + +
Sbjct: 298 ELLLDLPIKDYWFVAQAELIIDGIDDVEEFQLTDEAFDILNFSAVEKQDCYRLMSAHMHM 357
Query: 1090 GNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQ 1269
GN++F Q + +QA +K ++ G+ E KA +PR+KVG E+V+K QN EQ
Sbjct: 358 GNMKFKQRPREEQAEPDGTDEAEKASNMYGIGCEEFLKALTKPRVKVGTEWVSKGQNCEQ 417
Query: 1270 AEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICI 1449
+AV A+AK Y R+F WLV + N +LD+ FIG+LDIAGFEIFD NSFEQ+ I
Sbjct: 418 VNWAVGAMAKGLYSRVFNWLVKKCNLTLDQKGIDRDYFIGVLDIAGFEIFDFNSFEQLWI 477
Query: 1450 NYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEEC 1629
N+ NEKLQQ FN+ MF+LEQEEY REGI+W FIDFGLDLQ I+LIEKP+G++++LDEEC
Sbjct: 478 NFVNEKLQQFFNHHMFVLEQEEYAREGIQWVFIDFGLDLQACIELIEKPLGIISMLDEEC 537
Query: 1630 LFPKANDKSFVEKLQKTH-NKHPKFIVP----DMRSKSHFAVVHYAGRVDYSADQWLMKN 1794
+ PKA D + KL H KHP F P + ++HFA+ HYAG V Y+ WL KN
Sbjct: 538 IVPKATDLTLASKLVDQHLGKHPNFEKPKPPKGKQGEAHFAMRHYAGTVRYNCLNWLEKN 597
Query: 1795 MDPLNENVVGLM-QNSTDPFVAGIWKDAEFAGICAAEMNETAFG--MRSRKGMFRTVSQL 1965
DPLN+ VV M Q+ + + IW+D AA+ E G + + G F TVS L
Sbjct: 598 KDPLNDTVVSAMKQSKGNDLLVEIWQDYTTQEEAAAKAKEGGGGGKKKGKSGSFMTVSML 657
Query: 1966 HKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFP 2145
++E L LMT L T PHF+RCIIPN +K+SG I++ LVL QL CNGVLEGIRICR+GFP
Sbjct: 658 YRESLNNLMTMLNKTHPHFIRCIIPNEKKQSGMIDAALVLNQLTCNGVLEGIRICRKGFP 717
Query: 2146 NRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITAL----DIDTNLYRIGQSKVFFRT 2313
NR +F RY IL K+ D K+ +++ L + ++RIG +KVFF+
Sbjct: 718 NRTLHPDFVQRYAILAAKE-AKSDDDKKKCAEAIMSKLVNDGSLSEEMFRIGLTKVFFKA 776
Query: 2314 GVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNW 2493
GVLAHLE+ RD KL ++ FQ+Q R L + N ++ LR W
Sbjct: 777 GVLAHLEDIRDEKLATILTGFQSQIRWHLGLKDRKRRMEQRAGLLIVQRNVRSWCTLRTW 836
Query: 2494 QWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVI 2673
+W++L+ KVKP+L+ + +E+ +D+++A ++ L K E +E E+ +++ E+ +
Sbjct: 837 EWFKLYGKVKPMLKAGKEAEELEKINDKVKALEDSLAKEEKLRKELEESSAKLVEEKTSL 896
Query: 2674 QEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETV 2853
L+ ++ ++ +L+ + ++ ++++ D+L+ ++K V
Sbjct: 897 FTNLESTKTQLSDAEERLAKLEAQQKDASKQLSELNDQLADNEDRTADVQRAKKKIEAEV 956
Query: 2854 RDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLT 3033
+K + D +A L
Sbjct: 957 EALKKQIQDLEMSLRKAESEKQSKDHQIRSLQDEMQQQDEAIAKLNKEKKHQEEINRKLM 1016
Query: 3034 TQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLA 3213
L E++ H K K +LE L +LE L RE++ +++L++ KRK+ EL+ +++++
Sbjct: 1017 EDLQSEEDKGNHQNKVKAKLEQTLDDLEDSLEREKRARADLDKQKRKVEGELKIAQENID 1076
Query: 3214 EKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERN 3393
E + +L N L K++ EL +R ++E A V+ +Q+Q++D Q+ I EL E++E ER
Sbjct: 1077 ESGRQRHDLENNLKKKESELHSVSSRLEDEQALVSKLQRQIKDGQSRISELEEELENERQ 1136
Query: 3394 ARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTME 3570
+R+KA+ + ++ +LE++ G+ LD+ AT Q ++ +++ E+ +R +E+ E
Sbjct: 1137 SRSKADRAKSDLQRELEEL-GEKLDEQGGATAAQVEVNKKREAELAKLRRDLEEANMNHE 1195
Query: 3571 GKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADID 3750
++ + K + V EL DQ++Q K ++++EK + QA ++ D+A ++ + + + +
Sbjct: 1196 NQLGGLRKKHTDAVAELTDQLDQLNKAKAKVEKDKAQAVRDAEDLAAQLDQETSGKLNNE 1255
Query: 3751 KKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLA 3930
K K E L E+Q+ E + R E L R E+ E + R +
Sbjct: 1256 KLAKQFELQLTELQSKADEQSRQLQDFTSLKGRLHSENGDLVRQLEDAESQVNQLTRLKS 1315
Query: 3931 TAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHA-- 4101
R + +A+ + E L + +EE EG L + A
Sbjct: 1316 QLTSQLEEARRTADEEARERQTVAAQAKNYQHEAEQLQESLEEEIEGKNEILRQLSKANA 1375
Query: 4102 -----ARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKI 4266
+ GE KA+E LE+ +++ + + LQ+ L+ + + ++K ++
Sbjct: 1376 DIQQWKARFEGEGLLKADE-----LEDAKRRQAQKINELQEALDAANSKNASLEKTKSRL 1430
Query: 4267 QQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRV 4446
+L+D+ +++E EK+QK F+ + E R + D ++LR+ T +
Sbjct: 1431 VGDLDDAQVDVERANGVASALEKKQKGFDKIIDEWRKKTDDLAAELDGAQRDLRNTSTDL 1490
Query: 4447 LSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMR 4626
N + + E +E R +SL QE++D + G++VHE++K R LE E +++
Sbjct: 1491 FKAKNAQEELAEVVEGLRRENKSLSQEIKDLTDQLGEGGRSVHEMQKIIRRLEIEKEELQ 1550
Query: 4627 VQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENEL 4806
++E E L+ E LR +V ++SE ++ I K+ E E R+ + + ++ L
Sbjct: 1551 HALDEAEAALEAEESKVLRAQVEVSQIRSEIEKRIQEKEEEFENTRKNHARALESMQASL 1610
Query: 4807 ENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEAR 4986
E E +GK+ + +KK+E I ELE L+ AN+ + E Q++ EE +
Sbjct: 1611 ETEAKGKAELLRIKKKLEGDINELEIALDHANKANADAQKNLKRYQEQVRELQLQVEEEQ 1670
Query: 4987 QAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGG-IS 5163
+ D A+++ +++E+E+L ANE +ARKQ + +S
Sbjct: 1671 RNGADTREQFFNAEKRATLLQSEKEELLVANEAAERARKQAEYEAADARDQANEANAQVS 1730
Query: 5164 S--EEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEA 5337
S KR+LE +I + + A ++ +KA ++ +L E+ +Q +
Sbjct: 1731 SLTSAKRKLEGEIQAIHADLDETLNEYKAAEERSKKAIADATRLAEELRQEQEHSQHVDR 1790
Query: 5338 EKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAAR 5517
++ LE+ ++ + ++ E E+ A + +A LE +V+ LE +L+ E + AN+
Sbjct: 1791 LRKGLEQQLKEIQVRLDEAEAAALKGGKKVIAKLEQRVRELESELDGEQRRFQDANKNLG 1850
Query: 5518 RLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQR 5697
R ++R+ + Q +++K+ E+ ++L++K K + ++Q++EAE+ + K++ +
Sbjct: 1851 RADRRVRELQFQVDEDKKNFERLQDLIDKLQQKLKTQKKQVEEAEELANLNLQKYKQLTH 1910
Query: 5698 EADDLLDANEQLTREL 5745
+ +D + +Q L
Sbjct: 1911 QLEDAEERADQAENSL 1926
Score = 70.1 bits (170), Expect = 6e-10
Identities = 96/479 (20%), Positives = 191/479 (39%), Gaps = 65/479 (13%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLM 3255
KAK E +L E+ + L RE + S+ E++D D L E V E+ +
Sbjct: 1492 KAKNAQE-ELAEVVEGLRRENKSLSQ----------EIKDLTDQLGEGGRSVHEMQKIIR 1540
Query: 3256 KRD---EELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETE-RNARNKAEMTRR 3423
+ + EELQH L DE A + + ++ Q + ++R ++E + + E TR+
Sbjct: 1541 RLEIEKEELQHAL---DEAEAALEAEESKVLRAQVEVSQIRSEIEKRIQEKEEEFENTRK 1597
Query: 3424 EVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQK--AK 3597
LE ++ + + L + + + ++N + A++ H + + QK +
Sbjct: 1598 NHARALESMQASLETEAKGKAELLRIKKKLEGDINELEIALD---HANKANADAQKNLKR 1654
Query: 3598 FSRQVEELHDQIEQHKKQ----RSQL------------------------EKQQNQADQE 3693
+ QV EL Q+E+ ++ R Q E+ + QA+ E
Sbjct: 1655 YQEQVRELQLQVEEEQRNGADTREQFFNAEKRATLLQSEKEELLVANEAAERARKQAEYE 1714
Query: 3694 RADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAES-DEHKRT-------------L 3831
AD + A + + ++ E + I A+L E+ +E+K L
Sbjct: 1715 AADARDQANEANAQVSSLTSAKRKLEGEIQAIHADLDETLNEYKAAEERSKKAIADATRL 1774
Query: 3832 IDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANIN-R 4008
++L + ++ H++R+R+ E +Q RL A + IA + R
Sbjct: 1775 AEELRQEQEHSQHVDRLRKGLEQQLKEIQVRLDEAEAAALKGG-------KKVIAKLEQR 1827
Query: 4009 ARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARR----------------KAE 4140
R+LE E + ++A ++ + + E ++ K +
Sbjct: 1828 VRELESELDGEQRRFQDANKNLGRADRRVRELQFQVDEDKKNFERLQDLIDKLQQKLKTQ 1887
Query: 4141 ESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRAS 4317
+ ++ EEL NL+ + L QLE++E ++ S K++ + S+ +++S
Sbjct: 1888 KKQVEEAEELANLNLQKYKQLTHQLEDAEERADQAENSLSKMRSKSRASASVAPGLQSS 1946
>gi|2351219|dbj|BAA22067.1| myosin heavy chain [Cyprinus carpio]
Length = 1933
Score = 1088 bits (2815), Expect = 0.0
Identities = 634/1864 (34%), Positives = 1047/1864 (56%), Gaps = 20/1864 (1%)
Frame = +1
Query: 178 RQVTISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVIN 357
+ VT+ D++ NPPKFDK+EDM+ LT+LNE SVL NLKDRY + +IYTYSGLFC +N
Sbjct: 67 KTVTVKEDEIFPMNPPKFDKMEDMAMLTHLNEPSVLFNLKDRYAAWMIYTYSGLFCATVN 126
Query: 358 PYKKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTE 537
PYK LP+Y ++ ++GKKR E PPHIF+I+D AY+ ML +RE+QS+L TGESGAGKT
Sbjct: 127 PYKWLPVYDAVVVAGYRGKKRIEAPPHIFSISDNAYQFMLTDRENQSVLITGESGAGKTV 186
Query: 538 NTKKVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSK 717
NTK+VIQY A +A A K+ + G LE Q++ ANP+LEA+GN+K
Sbjct: 187 NTKRVIQYFATIAMAGPKKAEAVPGKMQ-----------GSLEDQIIAANPLLEAYGNAK 235
Query: 718 TVKNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCS 897
T++NDNSSRFGKFIRI+F +G ++ A+IE YLLEKSRV Q ERS+HIFYQ++ G
Sbjct: 236 TIRNDNSSRFGKFIRIHFSGTGKLAKADIETYLLEKSRVTFQLSAERSYHIFYQLMTG-H 294
Query: 898 AKEKSEYLLEGVDNYRF-LVNRG-ITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVV 1071
E E LL + Y + ++++G IT+ ++DDV+EF +T ++ I+GF DE SI ++
Sbjct: 295 KPELLEALLITTNPYDYPMISQGEITVKSIDDVEEFIATDTAIDILGFTADEKISIYKLT 354
Query: 1072 SAVLLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNK 1251
AV+ G ++F Q+++ +QA + K+ +L+G+ ++ KA PR+KVG E V K
Sbjct: 355 GAVMHHGAMKFKQKQREEQAEPDGNEAADKIAYLMGINSADMLKALCYPRVKVGNEMVTK 414
Query: 1252 AQNQEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINS 1431
Q Q AV A+ K+ YE++F W+V RIN+ L+ T+ + +IG+LDIAGFEIFD NS
Sbjct: 415 GQTVPQVNNAVSALCKSVYEKMFLWMVVRINEMLNTTNPR-EYYIGVLDIAGFEIFDFNS 473
Query: 1432 FEQICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLA 1611
EQ+CIN+TNEKLQQ FN+TMF+LEQEEY++EGIEW FIDFG+DL I+LIEKPMG+ +
Sbjct: 474 LEQLCINFTNEKLQQFFNHTMFVLEQEEYKKEGIEWAFIDFGMDLAACIELIEKPMGIFS 533
Query: 1612 LLDEECLFPKANDKSFVEKLQKTH-NKHPKFIVPDM---RSKSHFAVVHYAGRVDYSADQ 1779
+L+EEC+FPKA D SF KL H K F P ++++HF++VHYAG VDY+ +
Sbjct: 534 ILEEECMFPKATDTSFKNKLHDQHLGKCSAFQKPKPGKGKAEAHFSLVHYAGTVDYNING 593
Query: 1780 WLMKNMDPLNENVVGLMQNSTDPFVAGIW---KDAEFAGICAAEMNETAFGMRSRKGMFR 1950
WL KN DPLN++VV L Q S +A ++ +AE AG G + + G F+
Sbjct: 594 WLEKNKDPLNDSVVQLYQKSALKVLALLYVAVPEAEAAG---------KKGGKKKGGSFQ 644
Query: 1951 TVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRIC 2130
TVS + +E L KLMT LR+T PHFVRC+IPN K G + + LV+ QLRCNGV+EGIRIC
Sbjct: 645 TVSAVFRENLGKLMTNLRSTHPHFVRCLIPNESKTPGLMENFLVIHQLRCNGVVEGIRIC 704
Query: 2131 RQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDGKESVRKMITALDIDTNLYRIGQSKVFF 2307
+GFP+R+ + +F+ RY++L VIP+ FID K++ K++ ++D+D N Y+ G +KVFF
Sbjct: 705 TKGFPSRIHYGDFKQRYKVLNASVIPEGQFIDNKKATEKLLGSIDVDHNQYKFGHTKVFF 764
Query: 2308 RTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLR 2487
+ G+L LEE RD KL+ L+ QA RG++ R+ + N +++ ++
Sbjct: 765 KAGLLGTLEEMRDEKLSHLVTMTQALARGYVMRKEFVKMMERREAIYSIQYNIRSFMNVK 824
Query: 2488 NWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERA 2667
+W W +++ K+KPLL+ ++ E+ + + KE L K +E E+K+ ++ E+
Sbjct: 825 HWPWMKVYFKIKPLLKTAESEKEMASMKENFEKMKEDLTKALAKKKELEEKMVSLVQEKN 884
Query: 2668 VIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQME 2847
+ Q+ ESEN ++ ++ L +LE + + +RL +RK +
Sbjct: 885 DLLLQVTSESENLSDAEERCEGLIKSKIQLEGKLKETTERLEDEEEINAELTAKKRKLED 944
Query: 2848 TVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXG 3027
+ +K + ++
Sbjct: 945 ECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMASQDESIAKLTKEKKALQEAHQQ 1004
Query: 3028 LTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDH 3207
L E++ KAK +LE Q+ +LE L +E++ + +LE+ KRKL +L+ +++
Sbjct: 1005 TLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERVKRKLEGDLKLAQES 1064
Query: 3208 LAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETE 3387
+ + + ++ + ++ K+D E+ L++ ++E + +QK+++++Q I+EL E++E E
Sbjct: 1065 IMDLENEKQQSDEKIKKKDFEISQFLSKIEDEQSLGAQLQKKIKELQARIEELEEEIEAE 1124
Query: 3388 RNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHT 3564
R+AR K E R ++ +LE++ + L++ AT Q M++K E E +R +E+
Sbjct: 1125 RSARAKVEKQRADLSRELEEI-SERLEEAGGATAAQIEMNKKREAEFQKMRRDLEESTLQ 1183
Query: 3565 MEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRAD 3744
E + K + V EL +QI+ ++ + +LEK++++ E D++ + + ++ +
Sbjct: 1184 HEATAAALRKKQADSVAELGEQIDNLQRIKQKLEKEKSEYKMEIDDLSSNMEAVAKAKGN 1243
Query: 3745 IDKKRKIHEAHLMEIQANLAESDEHKRTLID---QLERSRDELDHLNRVREEEEHAFANM 3915
++K + E L EI+ A+SDE+ R L D Q R + E +R EE+E + +
Sbjct: 1244 LEKMCRTLEDQLSEIK---AKSDENSRQLNDMNAQRARLQTENGEFSRQLEEKEALVSQL 1300
Query: 3916 QRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEI 4095
R + K A + + + + L ++ EE + +A L++ +
Sbjct: 1301 TRGKQAFTQQIEDLKRHVEEEVKAKNALAHAVQSARHDCDLLREQYEEEQEAKAELQRGM 1360
Query: 4096 HAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKER---ILQSKKKI 4266
A + R K E Q+ EEL + + + LQ E E + + ++K+++
Sbjct: 1361 SKANSEVAQWRAKYETDAIQRTEELEESKKKLAQRLQDAEESIEAVNSKCASLEKTKQRL 1420
Query: 4267 QQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRV 4446
Q E+ED ++ E A + +K+Q+ F+ +A+ + +++ + +A +E R T +
Sbjct: 1421 QSEVEDLMIDGERANALAANLDKKQRNFDKVLADWKQKYEESQAELEAAQKEARSLSTEL 1480
Query: 4447 LSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMR 4626
+ N + +HLE R ++LQQE+ D + GK++HE+EKAK+++E+E +++
Sbjct: 1481 FKMKNSYEEALDHLETLKRENKNLQQEISDLSEQLGETGKSIHEIEKAKKTVESEKAEIQ 1540
Query: 4627 VQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENEL 4806
+EE E L+ E LR+++ +KSE DR ++ KD E E+ +R + + +++ L
Sbjct: 1541 TALEEAEGTLEHEESKILRVQLELNQVKSEIDRKLAEKDEEMEQIKRNSQRVLDSMQSTL 1600
Query: 4807 ENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEAR 4986
++E R ++ A+ +KK+E + E+E QL ANR E + Q+ +EA
Sbjct: 1601 DSEVRSRNDALRVKKKMEGDLNEMEVQLSHANRQAAEAQKQLRNVQGQLKDAQLHLDEAV 1660
Query: 4987 QAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARK---QXXXXXXXXXXXRAKGGG 5157
+ +ED+ + +R+ ++AE E+LR A E + RK Q
Sbjct: 1661 RGQEDMKEQVAMVERRNSLMQAEIEELRAALEQTERGRKVAEQELVDASERVGLLHSQNT 1720
Query: 5158 ISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEA 5337
K++LE + Q A +K +KA + +L E+ + E
Sbjct: 1721 SLINSKKKLETDLVQVQGEVDDAVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1780
Query: 5338 EKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAAR 5517
K+++E + +D + ++ E ES A + Q+ LE++V LE ++ E + A + R
Sbjct: 1781 MKKNMELTVKDLQHRLDEAESLAMKGGKKQLQKLESRVHELEAEVEAEQRRGADAVKGVR 1840
Query: 5518 RLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQR 5697
+ E+R+ + T Q E++K+ + ++L++ LK + +RQ +EAE++ + +++R VQ
Sbjct: 1841 KYERRVKELTYQTEEDKKNVTRLQDLVDNLQLKVKAYKRQAEEAEEQANTHLSRYRKVQH 1900
Query: 5698 EADD 5709
E ++
Sbjct: 1901 ELEE 1904
Score = 119 bits (298), Expect = 9e-25
Identities = 178/913 (19%), Positives = 365/913 (39%), Gaps = 127/913 (13%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ +E ++ +E++ +++++K+ + E + +++ E A+L LQ
Sbjct: 1052 RKLEGDLKLAQESIMDLENEKQQSDEKIKKKDFEISQFLSKIEDEQSLGAQLQKKIKELQ 1111
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + R + +++E + + +
Sbjct: 1112 ARIEELEEEIEAERSARAKVEKQRADLS----RELEEISERLEEAGGATAAQIEMNKKRE 1167
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K +
Sbjct: 1168 AEFQKMRRDLEESTLQHEATAAALRKKQADSVAELG---EQIDNLQRIKQKLEKEKSEYK 1224
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K LE+ R L +L + K E ++ ++N Q + E
Sbjct: 1225 MEIDDLSSNMEAVAKAKGNLEKMCRTLEDQLSEIKAKSDENSRQLNDMNAQRARLQTENG 1284
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ +E+ A V+ + + + I++L+ +E E A+N + + ++
Sbjct: 1285 EFSRQLEEKEALVSQLTRGKQAFTQQIEDLKRHVEEEVKAKNALAHAVQSARHDCDLLRE 1344
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
++ + LQ MS+ + EV K + IQ T E +EE K K ++++++ +
Sbjct: 1345 QYEEEQEAKAELQRGMSKANSEVAQWRAKYETDAIQRTEE--LEESKKKLAQRLQDAEES 1402
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLM-------EI 3789
IE + + LEK + + E D+ + A A++DKK++ + L E
Sbjct: 1403 IEAVNSKCASLEKTKQRLQSEVEDLMIDGERANALAANLDKKQRNFDKVLADWKQKYEES 1462
Query: 3790 QANLAESDEHKRTLIDQLERSRDE----LDHLNRVREEEEHAFANMQRRLATAXXXXXXX 3957
QA L + + R+L +L + ++ LDHL ++ E + N+Q+ ++
Sbjct: 1463 QAELEAAQKEARSLSTELFKMKNSYEEALDHLETLKRENK----NLQQEISDLSEQLGE- 1517
Query: 3958 XXXXXXXTRLKIANINRARQ-LEDEKNALLDEKEEAEGLRAHLEKEIHAAR----QGAGE 4122
T I I +A++ +E EK + EEAEG H E +I + Q E
Sbjct: 1518 -------TGKSIHEIEKAKKTVESEKAEIQTALEEAEGTLEHEESKILRVQLELNQVKSE 1570
Query: 4123 ARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
RK E ++++E++++ + R ++ +Q L+ ++ L+ KKK++ +L + ++L
Sbjct: 1571 IDRKLAEK-DEEMEQIKRNSQRVLDSMQSTLDSEVRSRNDALRVKKKMEGDLNEMEVQLS 1629
Query: 4303 --------------NVRASHRDS---------------------EKRQKKFESQMAEERV 4377
NV+ +D+ E+R ++++ E R
Sbjct: 1630 HANRQAAEAQKQLRNVQGQLKDAQLHLDEAVRGQEDMKEQVAMVERRNSLMQAEIEELRA 1689
Query: 4378 AVQKALLDRDAMSQELRDRETRV-------LSLLN-----EVDIMKEHLEESDRVR--RS 4515
A+++ R QEL D RV SL+N E D+++ E D V+ R+
Sbjct: 1690 ALEQTERGRKVAEQELVDASERVGLLHSQNTSLINSKKKLETDLVQVQGEVDDAVQEARN 1749
Query: 4516 LQQELQDSISN--------KDDFGKNVHELEKAKRSLEAELNDMRVQMEELED------- 4650
+++ + +I++ K + + H LE+ K+++E + D++ +++E E
Sbjct: 1750 AEEKAKKAITDAAMMAEELKKEQDTSAH-LERMKKNMELTVKDLQHRLDEAESLAMKGGK 1808
Query: 4651 -NLQIAEDARLRLEVTNQA-----------------------LKSESDR----------- 4725
LQ E LE +A ++E D+
Sbjct: 1809 KQLQKLESRVHELEAEVEAEQRRGADAVKGVRKYERRVKELTYQTEEDKKNVTRLQDLVD 1868
Query: 4726 -------AISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKK--IENQIGEL 4878
A + EAEE+ L + R +++ELE SH + E+Q+ +L
Sbjct: 1869 NLQLKVKAYKRQAEEAEEQANTHLSRYRKVQHELEE---------SHERADIAESQVNKL 1919
Query: 4879 EQQLEVANRLKEE 4917
+ A + K E
Sbjct: 1920 RAKSREAGKTKVE 1932
Score = 79.7 bits (195), Expect = 8e-13
Identities = 109/565 (19%), Positives = 230/565 (40%), Gaps = 4/565 (0%)
Frame = +1
Query: 4057 EAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN--LRDVEHLQKQLEESEV 4230
E+E A +++ ++ +A K +E + + +++KN L V + L ++E
Sbjct: 843 ESEKEMASMKENFEKMKEDLTKALAKKKELEEKMVSLVQEKNDLLLQVTSESENLSDAEE 902
Query: 4231 AKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDA 4410
E +++SK +++ +L++++ LE+ + + +++K E + +E + + L
Sbjct: 903 RCEGLIKSKIQLEGKLKETTERLEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAK 962
Query: 4411 MSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKA 4590
+ +E E +V +L E+ E + + + +++LQ+ Q ++ + V+ L KA
Sbjct: 963 VEKEKHATENKVKNLTEEMASQDESIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKA 1022
Query: 4591 KRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRG 4770
K LE +++D+ +E+ + +LR+++ K E D ++ + +
Sbjct: 1023 KTKLEQQVDDLEGSLEQ---------EKKLRMDLERVKRKLEGDLKLAQESIM------- 1066
Query: 4771 LLKQIRDLENELENEKRGKSGAVSHRK-KIENQIGELEQQLEVANRLKEEYXXXXXXXXX 4947
+LENEK+ + + +I + ++E + + +L+++
Sbjct: 1067 ----------DLENEKQQSDEKIKKKDFEISQFLSKIEDEQSLGAQLQKKIK-------- 1108
Query: 4948 XXXEYQIECEEARQAKEDIAALLREADRKFRA-VEAEREQLREANEGLMQARKQXXXXXX 5124
E Q EE +E+I EA+R RA VE +R L E + + ++
Sbjct: 1109 ---ELQARIEEL---EEEI-----EAERSARAKVEKQRADLSRELEEISERLEEAGGATA 1157
Query: 5125 XXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLS 5304
K + +R LE Q + KQ + +L + +L
Sbjct: 1158 AQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRK-------KQADSVAELGEQIDNL- 1209
Query: 5305 MERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEG 5484
+ KQ LE+ +YK +I +L S ++ A+A+ LE + LEDQL+
Sbjct: 1210 ---------QRIKQKLEKEKSEYKMEIDDLSSNMEAVAKAK-GNLEKMCRTLEDQLS--- 1256
Query: 5485 QEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMS 5664
E+ KS+ + RQL++ + +
Sbjct: 1257 -----------------------------------EIKAKSDENS----RQLNDMNAQRA 1277
Query: 5665 RERTKHRNVQREADDLLDANEQLTR 5739
R +T++ R+ ++ QLTR
Sbjct: 1278 RLQTENGEFSRQLEEKEALVSQLTR 1302
>gi|127743|sp|P02566|MYSB_CAEEL Myosin heavy chain B (MHC B)
gi|156400|gb|AAA28124.1| myosin heavy chain [Caenorhabditis elegans]
Length = 1966
Score = 1088 bits (2814), Expect = 0.0
Identities = 651/1938 (33%), Positives = 1051/1938 (53%), Gaps = 27/1938 (1%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSR--QV 186
QYL+ R V + + + +K W+PD EG+L G I D+V + QV
Sbjct: 10 QYLRRTREQVLEDQS-KPYDSKKNVWIPDPEEGYLAGEITATKGDQVTIVTAREMSVIQV 68
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
T+ ++ VQ+ NPPKF+K EDMS L++LN+ASVLHNL+ RY + LIYTYSGLFCVVINPYK
Sbjct: 69 TLKKELVQEMNPPKFEKTEDMSNLSFLNDASVLHNLRSRYAAMLIYTYSGLFCVVINPYK 128
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
+LPIY++ F GK++ EMPPH+FA++D AYR+MLQ+ E+QS+L TGESGAGKTENTK
Sbjct: 129 RLPIYTDSCARMFMGKRKTEMPPHLFAVSDEAYRNMLQDHENQSMLITGESGAGKTENTK 188
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVI Y A V A+QQ + D LE Q++Q NP+LEAFGN+KTV+
Sbjct: 189 KVICYFAAVG----------ASQQEGGAEVDPNKKKVTLEDQIVQTNPVLEAFGNAKTVR 238
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
N+NSSRFGKFIRI+F+ G ++ +IE YLLEKSRV+RQA ER +HIFYQI +
Sbjct: 239 NNNSSRFGKFIRIHFNKHGRLASCDIEHYLLEKSRVIRQAPGERCYHIFYQIYSDFRPEL 298
Query: 907 KSEYLLE-GVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVL 1083
K E LL+ + +Y F+ + + +DDV+EF T + I+ F+ E R++SA +
Sbjct: 299 KKELLLDLPIKDYWFVAQAELIIDGIDDVEEFQLTDEAFDILNFSAVEKQDCYRLMSAHM 358
Query: 1084 LLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQ 1263
+GN++F Q + +QA +K ++ G+ E KA +PR+KVG E+V+K QN
Sbjct: 359 HMGNMKFKQRPREEQAEPDGTVEAEKASNMYGIGCEEFLKALTKPRVKVGTEWVSKGQNC 418
Query: 1264 EQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQI 1443
EQ +AV A+AK Y R+F WLV + N +LD+ FIG+LDIAGFEIFD NSFEQ+
Sbjct: 419 EQVNWAVGAMAKGLYSRVFNWLVKKCNLTLDQKGIDRDYFIGVLDIAGFEIFDFNSFEQL 478
Query: 1444 CINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDE 1623
IN+ NEKLQQ FN+ MF+LEQEEY REGI+W FIDFGLDLQ I+LIEKP+G++++LDE
Sbjct: 479 WINFVNEKLQQFFNHHMFVLEQEEYAREGIQWVFIDFGLDLQACIELIEKPLGIISMLDE 538
Query: 1624 ECLFPKANDKSFVEKLQKTH-NKHPKFIVP----DMRSKSHFAVVHYAGRVDYSADQWLM 1788
EC+ PKA D + KL H KHP F P + ++HFA+ HYAG V Y+ WL
Sbjct: 539 ECIVPKATDLTLASKLVDQHLGKHPNFEKPKPPKGKQGEAHFAMRHYAGTVRYNCLNWLE 598
Query: 1789 KNMDPLNENVVGLM-QNSTDPFVAGIWKDAEFAGICAAEMNETAFG--MRSRKGMFRTVS 1959
KN DPLN+ VV M Q+ + + IW+D AA+ E G + + G F TVS
Sbjct: 599 KNKDPLNDTVVSAMKQSKGNDLLVEIWQDYTTQEEAAAKAKEGGGGGKKKGKSGSFMTVS 658
Query: 1960 QLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQG 2139
L++E L LMT L T PHF+RCIIPN +K+SG I++ LVL QL CNGVLEGIRICR+G
Sbjct: 659 MLYRESLNNLMTMLNKTHPHFIRCIIPNEKKQSGMIDAALVLNQLTCNGVLEGIRICRKG 718
Query: 2140 FPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITAL----DIDTNLYRIGQSKVFF 2307
FPNR +F RY IL K+ D K+ +++ L + ++RIG +KVFF
Sbjct: 719 FPNRTLHPDFVQRYAILAAKE-AKSDDDKKKCAEAIMSKLVNDGSLSEEMFRIGLTKVFF 777
Query: 2308 RTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLR 2487
+ GVLAHLE+ RD KL ++ FQ+Q R L + N ++ LR
Sbjct: 778 KAGVLAHLEDIRDEKLATILTGFQSQIRWHLGLKDRKRRMEQRAGLLIVQRNVRSWCTLR 837
Query: 2488 NWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERA 2667
W+W++L+ KVKP+L+ + +E+ +D+++A ++ L K E +E E+ +++ E+
Sbjct: 838 TWEWFKLYGKVKPMLKAGKEAEELEKINDKVKALEDSLAKEEKLRKELEESSAKLVEEKT 897
Query: 2668 VIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQME 2847
+ L+ ++ ++ +L+ + ++ ++++ D+L+ ++K
Sbjct: 898 SLFTNLESTKTQLSDAEERLAKLEAQQKDASKQLSELNDQLADNEDRTADVQRAKKKIEA 957
Query: 2848 TVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXG 3027
V +K + D +A
Sbjct: 958 EVEALKKQIQDLEMSLRKAESEKQSKDHQIRSLQDEMQQQDEAIAKLNKEKKHQEEINRK 1017
Query: 3028 LTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDH 3207
L L E++ H K K +LE L +LE L RE++ +++L++ KRK+ EL+ ++++
Sbjct: 1018 LMEDLQSEEDKGNHQNKVKAKLEQTLDDLEDSLEREKRARADLDKQKRKVEGELKIAQEN 1077
Query: 3208 LAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETE 3387
+ E + +L N L K++ EL +R ++E A V+ +Q+Q++D Q+ I EL E++E E
Sbjct: 1078 IDESGRQRHDLENNLKKKESELHSVSSRLEDEQALVSKLQRQIKDGQSRISELEEELENE 1137
Query: 3388 RNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHT 3564
R +R+KA+ + ++ +LE++ G+ LD+ AT Q ++ +++ E+ +R +E+
Sbjct: 1138 RQSRSKADRAKSDLQRELEEL-GEKLDEQGGATAAQVEVNKKREAELAKLRRDLEEANMN 1196
Query: 3565 MEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRAD 3744
E ++ + K + V EL DQ++Q K ++++EK + QA ++ D+A ++ + + +
Sbjct: 1197 HENQLGGLRKKHTDAVAELTDQLDQLNKAKAKVEKDKAQAVRDAEDLAAQLDQETSGKLN 1256
Query: 3745 IDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRR 3924
+K K E L E+Q+ E + R E L R E+ E + R
Sbjct: 1257 NEKLAKQFELQLTELQSKADEQSRQLQDFTSLKGRLHSENGDLVRQLEDAESQVNQLTRL 1316
Query: 3925 LATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHA 4101
+ R + +A+ + E L + +EE EG L + A
Sbjct: 1317 KSQLTSQLEEARRTADEEARERQTVAAQAKNYQHEAEQLQESLEEEIEGKNEILRQLSKA 1376
Query: 4102 -------ARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKK 4260
+ GE KA+E LE+ +++ + + LQ+ L+ + + ++K
Sbjct: 1377 NADIQQWKARFEGEGLLKADE-----LEDAKRRQAQKINELQEALDAANSKNASLEKTKS 1431
Query: 4261 KIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRET 4440
++ +L+D+ +++E EK+QK F+ + E R + D ++LR+ T
Sbjct: 1432 RLVGDLDDAQVDVERANGVASALEKKQKGFDKIIDEWRKKTDDLAAELDGAQRDLRNTST 1491
Query: 4441 RVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELND 4620
+ N + + E +E R +SL QE++D + G++VHE++K R LE E +
Sbjct: 1492 DLFKAKNAQEELAEVVEGLRRENKSLSQEIKDLTDQLGEGGRSVHEMQKIIRRLEIEKEE 1551
Query: 4621 MRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLEN 4800
++ ++E E L+ E LR +V ++SE ++ I K+ E E R+ + + ++
Sbjct: 1552 LQHALDEAEAALEAEESKVLRAQVEVSQIRSEIEKRIQEKEEEFENTRKNHARALESMQA 1611
Query: 4801 ELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEE 4980
LE E +GK+ + +KK+E I ELE L+ AN+ + E Q++ EE
Sbjct: 1612 SLETEAKGKAELLRIKKKLEGDINELEIALDHANKANADAQKNLKRYQEQVRELQLQVEE 1671
Query: 4981 ARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGG- 5157
++ D A+++ +++E+E+L ANE +ARKQ +
Sbjct: 1672 EQRNGADTREQFFNAEKRATLLQSEKEELLVANEAAERARKQAEYEAADARDQANEANAQ 1731
Query: 5158 ISS--EEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKT 5331
+SS KR+LE +I + + A ++ +KA ++ +L E+ +Q
Sbjct: 1732 VSSLTSAKRKLEGEIQAIHADLDETLNEYKAAEERSKKAIADATRLAEELRQEQEHSQHV 1791
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRA 5511
+ ++ LE+ ++ + ++ E E+ A + +A LE +V+ LE +L+ E + AN+
Sbjct: 1792 DRLRKGLEQQLKEIQVRLDEAEAAALKGGKKVIAKLEQRVRELESELDGEQRRFQDANKN 1851
Query: 5512 ARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNV 5691
R ++R+ + Q +++K+ E+ ++L++K K + ++Q++EAE+ + K++ +
Sbjct: 1852 LGRADRRVRELQFQVDEDKKNFERLQDLIDKLQQKLKTQKKQVEEAEELANLNLQKYKQL 1911
Query: 5692 QREADDLLDANEQLTREL 5745
+ +D + +Q L
Sbjct: 1912 THQLEDAEERADQAENSL 1929
Score = 70.1 bits (170), Expect = 6e-10
Identities = 96/479 (20%), Positives = 191/479 (39%), Gaps = 65/479 (13%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLM 3255
KAK E +L E+ + L RE + S+ E++D D L E V E+ +
Sbjct: 1495 KAKNAQE-ELAEVVEGLRRENKSLSQ----------EIKDLTDQLGEGGRSVHEMQKIIR 1543
Query: 3256 KRD---EELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETE-RNARNKAEMTRR 3423
+ + EELQH L DE A + + ++ Q + ++R ++E + + E TR+
Sbjct: 1544 RLEIEKEELQHAL---DEAEAALEAEESKVLRAQVEVSQIRSEIEKRIQEKEEEFENTRK 1600
Query: 3424 EVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQK--AK 3597
LE ++ + + L + + + ++N + A++ H + + QK +
Sbjct: 1601 NHARALESMQASLETEAKGKAELLRIKKKLEGDINELEIALD---HANKANADAQKNLKR 1657
Query: 3598 FSRQVEELHDQIEQHKKQ----RSQL------------------------EKQQNQADQE 3693
+ QV EL Q+E+ ++ R Q E+ + QA+ E
Sbjct: 1658 YQEQVRELQLQVEEEQRNGADTREQFFNAEKRATLLQSEKEELLVANEAAERARKQAEYE 1717
Query: 3694 RADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAES-DEHKRT-------------L 3831
AD + A + + ++ E + I A+L E+ +E+K L
Sbjct: 1718 AADARDQANEANAQVSSLTSAKRKLEGEIQAIHADLDETLNEYKAAEERSKKAIADATRL 1777
Query: 3832 IDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANIN-R 4008
++L + ++ H++R+R+ E +Q RL A + IA + R
Sbjct: 1778 AEELRQEQEHSQHVDRLRKGLEQQLKEIQVRLDEAEAAALKGG-------KKVIAKLEQR 1830
Query: 4009 ARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARR----------------KAE 4140
R+LE E + ++A ++ + + E ++ K +
Sbjct: 1831 VRELESELDGEQRRFQDANKNLGRADRRVRELQFQVDEDKKNFERLQDLIDKLQQKLKTQ 1890
Query: 4141 ESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRAS 4317
+ ++ EEL NL+ + L QLE++E ++ S K++ + S+ +++S
Sbjct: 1891 KKQVEEAEELANLNLQKYKQLTHQLEDAEERADQAENSLSKMRSKSRASASVAPGLQSS 1949
>gi|2351221|dbj|BAA22068.1| myosin heavy chain [Cyprinus carpio]
Length = 1931
Score = 1086 bits (2808), Expect = 0.0
Identities = 642/1908 (33%), Positives = 1062/1908 (55%), Gaps = 22/1908 (1%)
Frame = +1
Query: 52 ATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKF 231
A A + + +V D E +L ++ + V+ + VT+ D++ + NPPKF
Sbjct: 26 AQTAPFDAKTAFFVTDAAEMYLKSTLVSREGGKATVK-THCGKTVTVKEDEIFQMNPPKF 84
Query: 232 DKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKG 411
DK+EDM+ +T+LNE SVL NLK+RY + +IYTYSGLFC +NPYK LP+Y ++ ++G
Sbjct: 85 DKMEDMAMMTHLNEPSVLFNLKERYAAWMIYTYSGLFCATVNPYKWLPVYDAVVVAGYRG 144
Query: 412 KKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVA--GAT 585
KKR E PPHIF+I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A VA G
Sbjct: 145 KKRIEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATVAMSGPK 204
Query: 586 RNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRI 765
+ +++ Q G LE Q++ ANP+LEA+GN+KT++NDNSSRFGKFIRI
Sbjct: 205 KTEAVPGKMQ-------------GSLEDQIIAANPLLEAYGNAKTIRNDNSSRFGKFIRI 251
Query: 766 NFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYR 945
+F +G ++ A+IE YLLEKSRV Q ERS+HIFYQ++ G E E LL + Y
Sbjct: 252 HFGTTGKLAKADIETYLLEKSRVTFQLSAERSYHIFYQLMTG-HKPELLEALLITTNPYD 310
Query: 946 F-LVNRG-ITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKK 1119
+ ++++G IT+ ++DDV+EF +T ++ I+GF DE SI ++ AV+ G+++F Q+++
Sbjct: 311 YPMISQGEITVKSIDDVEEFIATDTAIDILGFTADEKISIYKLTGAVMHHGSMKFKQKQR 370
Query: 1120 SDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAK 1299
+QA + K+ +LLG+ ++ KA PR+KVG E V K Q Q AV A+ K
Sbjct: 371 EEQAEPDGNEAADKIAYLLGINSADMLKALCYPRVKVGNEMVTKGQTVPQVNNAVSALCK 430
Query: 1300 ASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQL 1479
+ YE++F W+V RIN+ L+ T+ + +IG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ
Sbjct: 431 SIYEKMFLWMVVRINEMLNTTNPR-EFYIGVLDIAGFEIFDYNSLEQLCINFTNEKLQQF 489
Query: 1480 FNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSF 1659
FN+TMF+LEQEEY++EGIEW FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF
Sbjct: 490 FNHTMFVLEQEEYKKEGIEWAFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSF 549
Query: 1660 VEKLQKTH-NKHPKFIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGL 1827
KL H K F P + ++HF+++HYAG VDY+ WL KN DPLN++VV L
Sbjct: 550 KNKLHDQHLGKSAAFQKPKPAKGKPEAHFSLLHYAGTVDYNIAGWLEKNKDPLNDSVVQL 609
Query: 1828 MQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRN 2007
Q S +A ++ + E + + G F+TVS L +E L KLMT LR+
Sbjct: 610 YQKSALKVLALLY-------VAVPEEGGGKKAGKKKGGSFQTVSALFRENLAKLMTNLRS 662
Query: 2008 TSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEI 2187
T PHFVRC+IPN K G + + LV+ QLRCNGVLEGIRICR+GFP+R+ + +F+ RY+I
Sbjct: 663 THPHFVRCLIPNESKTPGLMENFLVIHQLRCNGVLEGIRICRKGFPSRIHYGDFKQRYKI 722
Query: 2188 LTPDVIPK-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTAL 2364
L VIP+ +FID K++ K++ ++D+D Y+ G +KVFF+ G+L LEE RD KL L
Sbjct: 723 LNASVIPEGHFIDNKKATEKLLGSIDVDHTQYKFGHTKVFFKAGLLGALEEMRDEKLVNL 782
Query: 2365 IMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTR 2544
+ QA RG++ R+ + N +++ +++W W +++ K+KPLL+
Sbjct: 783 VTMTQALARGYVMRKEFVKMMERREAIFSIQYNIRSFMNVKHWPWMKVYFKIKPLLKTAE 842
Query: 2545 TDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDI 2724
++ E+ + + KE L K +E E+K+ ++ E+ + Q+ ESEN + ++
Sbjct: 843 SEKEMASMKENFEKMKEDLTKALAKKKELEEKMVSLVQEKNDLLLQVTSESENLCDAEER 902
Query: 2725 RGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXX 2904
L +LE + + +RL +RK + +
Sbjct: 903 CEGLIKSKIQLEGKLKETNERLEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 962
Query: 2905 XXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAK 3084
+K + ++ L E++ KAK
Sbjct: 963 EKEKHATENKVKNLTEEMACQDESIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAK 1022
Query: 3085 GRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRD 3264
+LE Q+ +LE L +E++ + +LE+ KRKL +L+ +++ + + + ++ + ++ K+D
Sbjct: 1023 TKLEQQVDDLEGSLEQEKKLRMDLERVKRKLEGDLKLAQESIMDLENEKQQSDEKIKKKD 1082
Query: 3265 EELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLE 3444
E+ L++ ++E + +QK+++++Q I+EL E++E ER+AR K E R ++ +LE
Sbjct: 1083 FEISQFLSKIEDEQSLGAQLQKKIKELQARIEELEEEIEAERSARAKVEKQRADLSRELE 1142
Query: 3445 KVKGDVLDKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEEL 3621
++ + L++ AT Q M++K E + +R +E+ E + K + V EL
Sbjct: 1143 EI-SERLEEAGGATAAQIEMNKKREADFQKMRRDLEESTLQHEATAAALRKKQADTVAEL 1201
Query: 3622 HDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL 3801
+QI+ ++ + +LEK++++ E D+ + + ++ +++K + E L EI+
Sbjct: 1202 GEQIDNLQRVKQKLEKEKSEYKMEIDDLTSNMEAVAKAKGNLEKMCRTLEDQLSEIK--- 1258
Query: 3802 AESDEHKRTLID---QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXX 3972
A+SDE+ R L D Q R + E +R EE+E + + R
Sbjct: 1259 AKSDENSRQLNDMNAQRARLQTENGEFSRQLEEKEALVSQLTRGKQAFTQQIEDLQRHVE 1318
Query: 3973 XXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVN 4152
+ K A + + + + L ++ EE + + L++ + A + R K E
Sbjct: 1319 EEVKAKNALAHAVQSARHDCDLLREQYEEEQEAKTELQRGMSKANSEVAQWRAKYETDAI 1378
Query: 4153 QQLEELRKKNLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHR 4323
Q+ EEL + + + LQ E E + + ++K+++Q E+ED ++ E A
Sbjct: 1379 QRTEELEEAKKKLAQRLQDAEESIEAVSSKCASLEKTKQRLQGEVEDLMIDGERANALAA 1438
Query: 4324 DSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDR 4503
+ +K+Q+ F+ +AE + +++ + +A +E R T + + N + +HLE R
Sbjct: 1439 NLDKKQRNFDKVLAEWKQKYEESQAELEAAQKEARSLSTELFKMKNSYEEALDHLETLKR 1498
Query: 4504 VRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLR 4683
++LQQE+ D + GK++HELEKAK+ +E+E +++ +EE E L+ E LR
Sbjct: 1499 ENKNLQQEISDLSEQLGETGKSIHELEKAKKIVESEKAEIQTALEEAESTLEHEESKILR 1558
Query: 4684 LEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIEN 4863
+++ +KSE DR ++ KD E E+ +R + + +++ L++E R ++ A+ +KK+E
Sbjct: 1559 VQLELNQVKSEIDRKLAEKDEEIEQIKRNSQRVMDSMQSTLDSEIRSRNDALRVKKKMEG 1618
Query: 4864 QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRA 5043
+ E+E QL ANR E + Q+ +EA + +ED+ + +R+
Sbjct: 1619 DLNEMEVQLSHANRQAAEAQKQLRNVQGQLKDAQLHLDEAVRGQEDMKEQVAMVERRNTL 1678
Query: 5044 VEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEE------KRRLEAKIAQX 5205
++AE E+LR A E + RK + G + S+ K++LE + Q
Sbjct: 1679 MQAEIEELRAALEQTERGRK---VAEQELVDASERVGLLHSQNTSLINTKKKLETDLLQV 1735
Query: 5206 XXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKI 5385
A +K +KA + +L E+ + E K+++E + +D + ++
Sbjct: 1736 QGEVDDAVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEVTVKDLQHRL 1795
Query: 5386 TELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDE 5565
E ES A + Q+ LE++V LE ++ E + A + R+ E+R+ + T Q E++
Sbjct: 1796 DEAESLAMKGGKKQLQKLESRVHELEAEVEAEQRRGADAVKGVRKYERRVKELTYQTEED 1855
Query: 5566 KRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
K++ + ++L++K LK + +RQ +EAE++ + +++R VQ E ++
Sbjct: 1856 KKSVTRLQDLVDKLQLKVKAYKRQAEEAEEQANTHLSRYRKVQHELEE 1903
Score = 164 bits (414), Expect = 3e-38
Identities = 193/923 (20%), Positives = 385/923 (40%), Gaps = 37/923 (4%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELE-------QHKRKLLAELEDSKDHLAEKMGKVE 3234
K ++ ++++DL + K ELE Q K LL ++ ++L + + E
Sbjct: 845 KEMASMKENFEKMKEDLTKALAKKKELEEKMVSLVQEKNDLLLQVTSESENLCDAEERCE 904
Query: 3235 ELNNQLMKRDEELQHQLTRY-DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
L ++ + +L+ R DEE N L K+ R ++ EL++D++ E
Sbjct: 905 GLIKSKIQLEGKLKETNERLEDEEEINAELTAKK-RKLEDECSELKKDIDD-------LE 956
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E + +++ +E A + A +Q ++ +
Sbjct: 957 LTLAKVEKEKHATENKVKNLTEEMACQDESIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1016
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK 3753
+ + K K +QV++L +EQ KK R LE+ + + + + + I L+ + D+
Sbjct: 1017 TLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERVKRKLEGDLKLAQESIMDLENEKQQSDE 1076
Query: 3754 KRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLAT 3933
K K + + + + + E +++L QL++ EL R+ E EE A R
Sbjct: 1077 KIKKKDFEISQFLSKI----EDEQSLGAQLQKKIKELQ--ARIEELEEEIEAERSAR--- 1127
Query: 3934 AXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQG 4113
+++ + +R+LE E + L+E A + + K+ A Q
Sbjct: 1128 ---------------AKVEKQRADLSRELE-EISERLEEAGGATAAQIEMNKKREADFQ- 1170
Query: 4114 AGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELED 4284
+ RR EES Q LRKK V L +Q++ + K+++ + K + + E++D
Sbjct: 1171 --KMRRDLEESTLQHEATAAALRKKQADTVAELGEQIDNLQRVKQKLEKEKSEYKMEIDD 1228
Query: 4285 SSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNE 4464
+ +E V + + EK + E Q++E + D S++L D + L E
Sbjct: 1229 LTSNMEAVAKAKGNLEKMCRTLEDQLSEIKA-------KSDENSRQLNDMNAQRARLQTE 1281
Query: 4465 VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEEL 4644
LEE + + L + Q +D ++V E KAK +L + R + L
Sbjct: 1282 NGEFSRQLEEKEALVSQLTRGKQAFTQQIEDLQRHVEEEVKAKNALAHAVQSARHDCDLL 1341
Query: 4645 EDNLQIAEDARLRL---------EVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLE 4797
+ + ++A+ L EV K E+D AI + E EE ++ L ++++D E
Sbjct: 1342 REQYEEEQEAKTELQRGMSKANSEVAQWRAKYETD-AIQRTE-ELEEAKKKLAQRLQDAE 1399
Query: 4798 NELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRL-------KEEYXXXXXXXXXXXX 4956
+E + +++++ ++ +L E AN L + +
Sbjct: 1400 ESIEAVSSKCASLEKTKQRLQGEVEDLMIDGERANALAANLDKKQRNFDKVLAEWKQKYE 1459
Query: 4957 EYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXX 5136
E Q E E A++ ++ L + + E L+ N+ L Q
Sbjct: 1460 ESQAELEAAQKEARSLSTELFKMKNSYEEALDHLETLKRENKNLQQEISDLSEQLGET-- 1517
Query: 5137 XRAKGGGISSEEKRR--LEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSME 5310
G I EK + +E++ A+ +S E K + Q++L Q+ +++ +
Sbjct: 1518 ----GKSIHELEKAKKIVESEKAEIQTALEEAESTLEHEESKILRVQLELNQVKSEI--D 1571
Query: 5311 RTLNQKTEAEKQSLERSNRDYKAKITELESGAQSR--ARAQMAALEAKVQYLEDQLNVEG 5484
R L +K E +Q S R + + L+S +SR A +E + +E QL+
Sbjct: 1572 RKLAEKDEEIEQIKRNSQRVMDSMQSTLDSEIRSRNDALRVKKKMEGDLNEMEVQLSHAN 1631
Query: 5485 QEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMS 5664
++ A + R ++ +L D ++ R E KE + +N ++ +++E +
Sbjct: 1632 RQAAEAQKQLRNVQGQLKDAQLHLDEAVRGQEDMKEQVAMVERRNTLMQAEIEELRAALE 1691
Query: 5665 RERTKHRNVQREADDLLDANEQL 5733
+ + ++E L+DA+E++
Sbjct: 1692 QTERGRKVAEQE---LVDASERV 1711
Score = 118 bits (295), Expect = 2e-24
Identities = 177/913 (19%), Positives = 366/913 (39%), Gaps = 127/913 (13%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ +E ++ +E++ +++++K+ + E + +++ E A+L LQ
Sbjct: 1051 RKLEGDLKLAQESIMDLENEKQQSDEKIKKKDFEISQFLSKIEDEQSLGAQLQKKIKELQ 1110
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + R + +++E + + +
Sbjct: 1111 ARIEELEEEIEAERSARAKVEKQRADLS----RELEEISERLEEAGGATAAQIEMNKKRE 1166
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K +
Sbjct: 1167 ADFQKMRRDLEESTLQHEATAAALRKKQADTVAELG---EQIDNLQRVKQKLEKEKSEYK 1223
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K LE+ R L +L + K E ++ ++N Q + E
Sbjct: 1224 MEIDDLTSNMEAVAKAKGNLEKMCRTLEDQLSEIKAKSDENSRQLNDMNAQRARLQTENG 1283
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ +E+ A V+ + + + I++L+ +E E A+N + + ++
Sbjct: 1284 EFSRQLEEKEALVSQLTRGKQAFTQQIEDLQRHVEEEVKAKNALAHAVQSARHDCDLLRE 1343
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
++ + T LQ MS+ + EV K + IQ T E +EE K K ++++++ +
Sbjct: 1344 QYEEEQEAKTELQRGMSKANSEVAQWRAKYETDAIQRTEE--LEEAKKKLAQRLQDAEES 1401
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME-------I 3789
IE + + LEK + + E D+ + A A++DKK++ + L E
Sbjct: 1402 IEAVSSKCASLEKTKQRLQGEVEDLMIDGERANALAANLDKKQRNFDKVLAEWKQKYEES 1461
Query: 3790 QANLAESDEHKRTLIDQLERSRDE----LDHLNRVREEEEHAFANMQRRLATAXXXXXXX 3957
QA L + + R+L +L + ++ LDHL ++ E + N+Q+ ++
Sbjct: 1462 QAELEAAQKEARSLSTELFKMKNSYEEALDHLETLKRENK----NLQQEISDLSEQLGE- 1516
Query: 3958 XXXXXXXTRLKIANINRARQL-EDEKNALLDEKEEAEGLRAHLEKEIHAAR----QGAGE 4122
T I + +A+++ E EK + EEAE H E +I + Q E
Sbjct: 1517 -------TGKSIHELEKAKKIVESEKAEIQTALEEAESTLEHEESKILRVQLELNQVKSE 1569
Query: 4123 ARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
RK E ++++E++++ + R ++ +Q L+ ++ L+ KKK++ +L + ++L
Sbjct: 1570 IDRKLAEK-DEEIEQIKRNSQRVMDSMQSTLDSEIRSRNDALRVKKKMEGDLNEMEVQLS 1628
Query: 4303 --------------NVRASHRDS---------------------EKRQKKFESQMAEERV 4377
NV+ +D+ E+R ++++ E R
Sbjct: 1629 HANRQAAEAQKQLRNVQGQLKDAQLHLDEAVRGQEDMKEQVAMVERRNTLMQAEIEELRA 1688
Query: 4378 AVQKALLDRDAMSQELRDRETRV-------LSLLN-----EVDIMKEHLEESDRVR--RS 4515
A+++ R QEL D RV SL+N E D+++ E D V+ R+
Sbjct: 1689 ALEQTERGRKVAEQELVDASERVGLLHSQNTSLINTKKKLETDLLQVQGEVDDAVQEARN 1748
Query: 4516 LQQELQDSISN--------KDDFGKNVHELEKAKRSLEAELNDMRVQMEELED------- 4650
+++ + +I++ K + + H LE+ K+++E + D++ +++E E
Sbjct: 1749 AEEKAKKAITDAAMMAEELKKEQDTSAH-LERMKKNMEVTVKDLQHRLDEAESLAMKGGK 1807
Query: 4651 -NLQIAEDARLRLEVTNQA-----------------------LKSESDR----------- 4725
LQ E LE +A ++E D+
Sbjct: 1808 KQLQKLESRVHELEAEVEAEQRRGADAVKGVRKYERRVKELTYQTEEDKKSVTRLQDLVD 1867
Query: 4726 -------AISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKK--IENQIGEL 4878
A + EAEE+ L + R +++ELE SH + E+Q+ +L
Sbjct: 1868 KLQLKVKAYKRQAEEAEEQANTHLSRYRKVQHELEE---------SHERADIAESQVNKL 1918
Query: 4879 EQQLEVANRLKEE 4917
+ A + K+E
Sbjct: 1919 RAKSREAGKTKDE 1931
Score = 78.2 bits (191), Expect = 2e-12
Identities = 109/565 (19%), Positives = 229/565 (40%), Gaps = 4/565 (0%)
Frame = +1
Query: 4057 EAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN--LRDVEHLQKQLEESEV 4230
E+E A +++ ++ +A K +E + + +++KN L V + L ++E
Sbjct: 842 ESEKEMASMKENFEKMKEDLTKALAKKKELEEKMVSLVQEKNDLLLQVTSESENLCDAEE 901
Query: 4231 AKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDA 4410
E +++SK +++ +L++++ LE+ + + +++K E + +E + + L
Sbjct: 902 RCEGLIKSKIQLEGKLKETNERLEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAK 961
Query: 4411 MSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKA 4590
+ +E E +V +L E+ E + + + +++LQ+ Q ++ + V+ L KA
Sbjct: 962 VEKEKHATENKVKNLTEEMACQDESIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKA 1021
Query: 4591 KRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRG 4770
K LE +++D+ +E ++ +LR+++ K E D ++ + +
Sbjct: 1022 KTKLEQQVDDLEGSLE---------QEKKLRMDLERVKRKLEGDLKLAQESIM------- 1065
Query: 4771 LLKQIRDLENELENEKRGKSGAVSHRK-KIENQIGELEQQLEVANRLKEEYXXXXXXXXX 4947
+LENEK+ + + +I + ++E + + +L+++
Sbjct: 1066 ----------DLENEKQQSDEKIKKKDFEISQFLSKIEDEQSLGAQLQKKIK-------- 1107
Query: 4948 XXXEYQIECEEARQAKEDIAALLREADRKFRA-VEAEREQLREANEGLMQARKQXXXXXX 5124
E Q EE +E+I EA+R RA VE +R L E + + ++
Sbjct: 1108 ---ELQARIEEL---EEEI-----EAERSARAKVEKQRADLSRELEEISERLEEAGGATA 1156
Query: 5125 XXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLS 5304
K + +R LE Q + KQ +L + +L
Sbjct: 1157 AQIEMNKKREADFQKMRRDLEESTLQHEATAAALRK-------KQADTVAELGEQIDNL- 1208
Query: 5305 MERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEG 5484
+ KQ LE+ +YK +I +L S ++ A+A+ LE + LEDQL+
Sbjct: 1209 ---------QRVKQKLEKEKSEYKMEIDDLTSNMEAVAKAK-GNLEKMCRTLEDQLS--- 1255
Query: 5485 QEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMS 5664
E+ KS+ + RQL++ + +
Sbjct: 1256 -----------------------------------EIKAKSDENS----RQLNDMNAQRA 1276
Query: 5665 RERTKHRNVQREADDLLDANEQLTR 5739
R +T++ R+ ++ QLTR
Sbjct: 1277 RLQTENGEFSRQLEEKEALVSQLTR 1301
Score = 62.0 bits (149), Expect = 2e-07
Identities = 92/466 (19%), Positives = 189/466 (39%), Gaps = 28/466 (6%)
Frame = +1
Query: 4429 DRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEA 4608
+ E + S+ + MKE L ++ ++ L++++ + K+D V +++ +A
Sbjct: 842 ESEKEMASMKENFEKMKEDLTKALAKKKELEEKMVSLVQEKNDLLLQV--TSESENLCDA 899
Query: 4609 ELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESD--RAISNKDVEAEEKRRGLLKQ 4782
E E E ++ +L+ TN+ L+ E + ++ K + E++ L K
Sbjct: 900 E--------ERCEGLIKSKIQLEGKLKETNERLEDEEEINAELTAKKRKLEDECSELKKD 951
Query: 4783 IRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEY 4962
I DLE L ++ K K++N E+ Q E +L +E +
Sbjct: 952 IDDLELTLAKVEKEKHAT---ENKVKNLTEEMACQDESIAKLTKEKKALQEAHQQTLDDL 1008
Query: 4963 QIECEEARQAKEDIAALLREADRKFRAVEAER------EQLREANEGLMQARKQXXXXXX 5124
Q E ++ + L ++ D ++E E+ E+++ EG ++ ++
Sbjct: 1009 QAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERVKRKLEGDLKLAQESIMDLE 1068
Query: 5125 XXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLS 5304
S E+ ++ + +I+Q QS K ++ Q ++E++ ++
Sbjct: 1069 NEKQQ-------SDEKIKKKDFEISQFLSKIEDEQSLGAQLQKKIKELQARIEELEEEIE 1121
Query: 5305 MERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQM-AALEAKVQYLEDQLNVE 5481
ER+ K E ++ L R + ++ E+G + A+ +M EA Q + L
Sbjct: 1122 AERSARAKVEKQRADLSRELEEISERLE--EAGGATAAQIEMNKKREADFQKMRRDL--- 1176
Query: 5482 GQEKTAANRA-ARRLEKRLNDTTQQFEDEKRANEQAKELLEK-------------SNLK- 5616
+E T + A A L K+ DT + ++ ++ K+ LEK SN++
Sbjct: 1177 -EESTLQHEATAAALRKKQADTVAELGEQIDNLQRVKQKLEKEKSEYKMEIDDLTSNMEA 1235
Query: 5617 ----NRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
NL + ED++S + K R+ +D+ +L E
Sbjct: 1236 VAKAKGNLEKMCRTLEDQLSEIKAKSDENSRQLNDMNAQRARLQTE 1281
>gi|345377|pir||A45627 myosin heavy chain [similarity] - nematode
(Brugia malayi)
gi|156087|gb|AAA73080.1| [Brugia malayi myosin heavy chain gene,
complete cds.], gene product
Length = 1957
Score = 1082 bits (2799), Expect = 0.0
Identities = 645/1918 (33%), Positives = 1047/1918 (53%), Gaps = 19/1918 (0%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
QYL+ R +A + + +K CW+PD EG++ I D V V + +VTI
Sbjct: 15 QYLRQTREQMAAEQS-RPFDSKKNCWIPDAEEGYIAAEITSTKGDNVTV-VSARGNEVTI 72
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
+D +Q+ NPPKF+K EDMS LT+LN+ASVL+NL+ RY S LIYTYSGLFCVVINPYK+L
Sbjct: 73 KKDMLQEMNPPKFEKTEDMSNLTFLNDASVLYNLRSRYSSMLIYTYSGLFCVVINPYKRL 132
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIY++ + + GK+R EMPPH+FA++D AYR+ML + E+QS+L TGESGAGKTENTKKV
Sbjct: 133 PIYTDSVATMYMGKRRTEMPPHLFAVSDEAYRNMLVDHENQSMLITGESGAGKTENTKKV 192
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
I Y A V GA++NK+ ++ + LE Q++Q NP+LEAFGN+KTV+N+
Sbjct: 193 IAYFA-VVGASQNKN---QGEKKVT-----------LEDQIVQTNPVLEAFGNAKTVRNN 237
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRI+F G ++ +IE YLLEKSRV+RQA ER +HIFYQI + K
Sbjct: 238 NSSRFGKFIRIHFSRQGKVASCDIEHYLLEKSRVIRQAPGERCYHIFYQIFSEFNPTLKK 297
Query: 913 EYLLEG-VDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLL 1089
E L+ + NY F+ +T+ V+D +E T + I+ F+ +E + R+V+A++ +
Sbjct: 298 ELQLDQPLKNYYFVAQAELTIDGVNDKEEHQLTDEAFDILNFSPEEKMNCYRLVAAIMHM 357
Query: 1090 GNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQ 1269
G ++F Q + +QA +K + G+ E KA +PR+KVG E+V+K QN +Q
Sbjct: 358 GCMKFKQRPREEQAEPDGTDEAEKASAMYGIDTEEFLKALTKPRVKVGTEWVSKGQNVDQ 417
Query: 1270 AEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICI 1449
+AV A+AK Y R+FKWLV + NK+LD+ FIG+LDIAGFEIFD NSFEQ+ I
Sbjct: 418 VTWAVGAMAKGLYARIFKWLVNKCNKTLDQKGISRDYFIGVLDIAGFEIFDFNSFEQLWI 477
Query: 1450 NYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEEC 1629
N+ NEKLQQ FN+ MF+LEQEEY+REGI+W FIDFGLDLQ I+LIEKPMG++++LDEEC
Sbjct: 478 NFVNEKLQQFFNHHMFVLEQEEYEREGIQWTFIDFGLDLQACIELIEKPMGIISMLDEEC 537
Query: 1630 LFPKANDKSFVEKLQKTH-NKHPKFIVP----DMRSKSHFAVVHYAGRVDYSADQWLMKN 1794
+ PKA D + +KL H KHP F P +S+ HFA+ HYAG V Y+ WL KN
Sbjct: 538 IVPKATDLTLAQKLVDNHLGKHPNFEKPKPPKGKQSERHFAMKHYAGTVRYNVMNWLEKN 597
Query: 1795 MDPLNENVVGLMQNS-TDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHK 1971
DPLN+ VV M+ S T+ + IW+D AA + + + G F TVS +++
Sbjct: 598 KDPLNDTVVSTMKASKTNDLLVEIWQDYTTQEERAAAKDGGGGKKKGKSGSFLTVSMMYR 657
Query: 1972 EQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNR 2151
E L LM+ L T PHF+RCIIPN +K SG +++ LVL QL CNG LEGIRICR+GFPNR
Sbjct: 658 ESLNSLMSMLNMTHPHFIRCIIPNEKKTSGLLDAALVLNQLTCNGALEGIRICRKGFPNR 717
Query: 2152 VPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNL----YRIGQSKVFFRTGV 2319
+F+ RY +L K+ D K+S M++ L D L +R+G++KVFF+ GV
Sbjct: 718 NLHADFKQRYAVLAAKE-AKSEDDPKKSAEVMLSKLVNDGALTEENFRLGKTKVFFKAGV 776
Query: 2320 LAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQW 2499
LAHLE+ RD KL + FQA+ R F++ N A+ LR W W
Sbjct: 777 LAHLEDLRDQKLGEALTGFQARIRSFINLADRQRRMQQRHGLLVLQRNIRAWCVLRTWDW 836
Query: 2500 WRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQE 2679
+ ++ K+KP+L+ + +EI + +++ +E + E +E E +++ ER +
Sbjct: 837 FLIYGKIKPMLKCGKEGEEIEKMNQKIKELEENIANEEKARKELESNSTKLLEERNNVFN 896
Query: 2680 QLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRD 2859
+L+ +++DD RL T ++E ++++ +RL ++K V +
Sbjct: 897 ELEAAKAQLSDVDDRLNRLSTLKTDVEKQIHELEERLGDQEDRNSDLSRSKKKIENDVEN 956
Query: 2860 XXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQ 3039
DK + +Q + L
Sbjct: 957 LKKAIADLEIRLQKTDADKQSREQQIRTLQDEMQQQDENIAKLNKEKKHQEEINRKLMED 1016
Query: 3040 LLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEK 3219
L E++ + K KG+LE L +LE +L RE++ ++E+E+ KRK+ EL+ +++++ E
Sbjct: 1017 LQVEEDKGNYSFKLKGKLEQSLDDLEDNLEREKRGRNEIEKQKRKIGGELKVAQENMEEI 1076
Query: 3220 MGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNAR 3399
+ E+ + L K++ E Q TR +EE + ++ R Q I EL E++E ER +R
Sbjct: 1077 ERQRHEIESNLKKKESEAQAITTRLEEEQDLLGSLKTCQRTTQNRISELEEELENERQSR 1136
Query: 3400 NKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGK 3576
+KAE + ++ +LE++ GD LD+ AT Q ++ +++ E+ +R +E+ E +
Sbjct: 1137 SKAERAKSDLQRELEEL-GDRLDEQGGATAAQVEVNKKREAELAKLRRDLEEANMNHENQ 1195
Query: 3577 IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKK 3756
+ + K + V EL DQIEQ +K + +L+K + QA ++ D+ +I A+R + +K
Sbjct: 1196 LAAIRKKHNDAVAELGDQIEQAQKAKVKLKKTKIQAQRDAEDLVAQIDGETAARMNNEKL 1255
Query: 3757 RKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATA 3936
K +E + E+Q E + + R E L + EE E M R A
Sbjct: 1256 SKQYEIKIAELQTKCDEQNRQLQEFTTLKTRLNSENSDLGKQIEEAESQVNAMTRLKAQL 1315
Query: 3937 XXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGA 4116
R + + + + E + + EE ++ L K++ A
Sbjct: 1316 TSQLEEARRSLDEEARDRNNLAAQMKNYQHEIEQIRESMEEEIEAKSELMKQLSRANAEI 1375
Query: 4117 GEARRKAEES---VNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDS 4287
+ + + E + +LEE +K+ ++ + LQ+ L+ ++ + + ++K ++ +L+D+
Sbjct: 1376 QQWQTRFESEGLLKSDELEESKKRQMQKINELQEALDAAQFKHQLLGKTKSRLVSDLDDA 1435
Query: 4288 SMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEV 4467
M++E + EK+QK F+ + E + + D +E R+ T + L +E
Sbjct: 1436 QMDVERANSYASQLEKKQKGFDKVIDEWKRKTDDIAAEVDNAQREARNVSTELFKLKSEQ 1495
Query: 4468 DIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELE 4647
D + E +E R + L QE++D + G++V E++K R LE E ++++ ++E E
Sbjct: 1496 DEVLETIEGLRRENKELAQEIKDLTDQLGEGGRSVFEMQKIIRRLEVEKDELQHALDEAE 1555
Query: 4648 DNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGK 4827
L+ E LR +V +++E ++ I K+ E E +R + L LENE R K
Sbjct: 1556 AALEAEESKVLRAQVEVSQIRAEIEKRIQEKEEEFENSKRNRIYAGDSLNATLENETRSK 1615
Query: 4828 SGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIA 5007
+ + +KK+E+ I ELE L+ AN+ E E Q + E ++ +E+I
Sbjct: 1616 ADLMRLKKKLESDINELEIALDHANQANAEAQKNVKRYQDQIRELQQQVEMQQRNREEIR 1675
Query: 5008 ALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXX----XXXRAKGGGISSEEK 5175
+ + ++K +++E+E++ A + RKQ A+ +SS K
Sbjct: 1676 ENVSDMEKKATLLQSEKEEMSVAMVSSERTRKQSERDANEAHVQCNELSAQAESLSS-VK 1734
Query: 5176 RRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLE 5355
++LE ++ + + + ++ + A + L E+ + + + +++LE
Sbjct: 1735 KKLETELLAIQADLDETLNEYKASEERYKAASSDAALLAEQLRQEQENSLQNDRIRKALE 1794
Query: 5356 RSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRL 5535
++ +A++ E E+ A + +A L+++++ LE +L+ E + N++ + E+R+
Sbjct: 1795 SQLKEMQARLDEAEAAALKGGKKVIAKLQSRIRELESELDGEQRRYQETNKSLTKHERRI 1854
Query: 5536 NDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+ Q +++++ E+ ++L+EK K ++ ++Q++EAE+ + K R +Q + DD
Sbjct: 1855 RELQFQVDEDRKNAERTRDLIEKLQNKLKSQKKQIEEAEELANVNLQKFRQIQHQLDD 1912
Score = 121 bits (303), Expect = 2e-25
Identities = 146/779 (18%), Positives = 313/779 (39%), Gaps = 62/779 (7%)
Frame = +1
Query: 3571 GKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADID 3750
GK E+ K +++++EL + I +K R +LE + +ER ++ E+ +A +D+D
Sbjct: 850 GKEGEEIEKMNQKIKELEENIANEEKARKELESNSTKLLEERNNVFNELEAAKAQLSDVD 909
Query: 3751 KKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLA 3930
+ +++ + E +E L DQ +R+ D L+R +++ E+ N+++ +A
Sbjct: 910 DRLNRLSTLKTDVEKQIHELEER---LGDQEDRNSD----LSRSKKKIENDVENLKKAIA 962
Query: 3931 TAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLD-EKEEAEGLRAHLEKEIHAAR 4107
+ +I + Q +DE A L+ EK+ E + L +++
Sbjct: 963 DLEIRLQKTDADKQSREQ-QIRTLQDEMQQQDENIAKLNKEKKHQEEINRKLMEDL---- 1017
Query: 4108 QGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDS 4287
+ EE +L+ K + ++ L+ LE + + I + K+KI EL+ +
Sbjct: 1018 --------QVEEDKGNYSFKLKGKLEQSLDDLEDNLEREKRGRNEIEKQKRKIGGELKVA 1069
Query: 4288 SMELENVRASHRDSEKRQKKFES--QMAEERVAVQKALLDRDAMSQELRDRETRVLSLLN 4461
+E + + E KK ES Q R+ ++ LL Q R + R+ L
Sbjct: 1070 QENMEEIERQRHEIESNLKKKESEAQAITTRLEEEQDLLGSLKTCQ--RTTQNRISELEE 1127
Query: 4462 EVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE 4641
E++ ++ +++R + LQ+EL++ D+ G + + EAEL +R +EE
Sbjct: 1128 ELENERQSRSKAERAKSDLQRELEELGDRLDEQGGATAAQVEVNKKREAELAKLRRDLEE 1187
Query: 4642 ----------------------LEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVE-- 4749
L D ++ A+ A+++L+ T + +++ ++ D E
Sbjct: 1188 ANMNHENQLAAIRKKHNDAVAELGDQIEQAQKAKVKLKKTKIQAQRDAEDLVAQIDGETA 1247
Query: 4750 AEEKRRGLLKQ----IRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEE 4917
A L KQ I +L+ + + + R + + ++ ++ +L +Q+E A
Sbjct: 1248 ARMNNEKLSKQYEIKIAELQTKCDEQNRQLQEFTTLKTRLNSENSDLGKQIEEAESQVNA 1307
Query: 4918 YXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQA 5097
E + +E + + ++AA ++ + + E+ EA LM+
Sbjct: 1308 MTRLKAQLTSQLEEARRSLDEEARDRNNLAAQMKNYQHEIEQIRESMEEEIEAKSELMKQ 1367
Query: 5098 RKQXXXXXXXXXXXRAKGGGISSEE----KRRLEAKIAQXXXXXXXXQSNCELAIDKQRK 5265
+ G + S+E K+R KI + Q +L + +
Sbjct: 1368 LSRANAEIQQWQTRFESEGLLKSDELEESKKRQMQKINELQEALDAAQFKHQLLGKTKSR 1427
Query: 5266 AQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES---GAQSRAR----- 5421
L+ D+ + + E +++ ++ ++K K ++ + AQ AR
Sbjct: 1428 LVSDLDDAQMDVERANSYASQLEKKQKGFDKVIDEWKRKTDDIAAEVDNAQREARNVSTE 1487
Query: 5422 -------------------AQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDT 5544
+ L +++ L DQL G+ + RRLE ++
Sbjct: 1488 LFKLKSEQDEVLETIEGLRRENKELAQEIKDLTDQLGEGGRSVFEMQKIIRRLEVEKDEL 1547
Query: 5545 TQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDA 5721
++ + A E + + ++ ++ +R ++++ E E + + A D L+A
Sbjct: 1548 QHALDEAEAALEAEESKVLRAQVEVSQIRAEIEKRIQEKEEEFENSKRNRIYAGDSLNA 1606
Score = 85.9 bits (211), Expect = 1e-14
Identities = 100/490 (20%), Positives = 208/490 (42%), Gaps = 50/490 (10%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAE---KMGKVEELNNQLMKR 3261
+ +L +L+ + + + L + ++L E++D D L E + +++++ +L
Sbjct: 1484 VSTELFKLKSEQDEVLETIEGLRRENKELAQEIKDLTDQLGEGGRSVFEMQKIIRRLEVE 1543
Query: 3262 DEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETE-RNARNKAEMTRREVVAQ 3438
+ELQH L DE A + + ++ Q + ++R ++E + + E ++R +
Sbjct: 1544 KDELQHAL---DEAEAALEAEESKVLRAQVEVSQIRAEIEKRIQEKEEEFENSKRNRIYA 1600
Query: 3439 LEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQK--AKFSRQV 3612
+ + + ++ L L + + ++N + A++ H + E QK ++ Q+
Sbjct: 1601 GDSLNATLENETRSKADLMRLKKKLESDINELEIALD---HANQANAEAQKNVKRYQDQI 1657
Query: 3613 EELHDQIEQHKKQR-------SQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHE 3771
EL Q+E ++ R S +EK+ E+ +M+ +A++ + R +R +E
Sbjct: 1658 RELQQQVEMQQRNREEIRENVSDMEKKATLLQSEKEEMS--VAMVSSERTRKQSERDANE 1715
Query: 3772 AH-----------------------LMEIQANLAES-DEHKRT-------------LIDQ 3840
AH L+ IQA+L E+ +E+K + L +Q
Sbjct: 1716 AHVQCNELSAQAESLSSVKKKLETELLAIQADLDETLNEYKASEERYKAASSDAALLAEQ 1775
Query: 3841 LERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQL 4020
L + ++ +R+R+ E MQ RL A + +R R+L
Sbjct: 1776 LRQEQENSLQNDRIRKALESQLKEMQARLDEAEAAALKGGKKVIAKLQ------SRIREL 1829
Query: 4021 EDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEH 4200
E E + +E E+ I + E R+ AE + +E+L+ K ++
Sbjct: 1830 ESELDGEQRRYQETNKSLTKHERRIRELQFQVDEDRKNAERT-RDLIEKLQNK----LKS 1884
Query: 4201 LQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVA 4380
+KQ+EE+E LQ ++IQ +L+D+ ++ A + S+ R K A V
Sbjct: 1885 QKKQIEEAEELANVNLQKFRQIQHQLDDAEERADH--AENSLSKMRAKSRSGMTASPGVQ 1942
Query: 4381 VQKALLDRDA 4410
+ ++ + R +
Sbjct: 1943 ISQSSILRSS 1952
Score = 73.2 bits (178), Expect = 7e-11
Identities = 100/412 (24%), Positives = 179/412 (43%), Gaps = 31/412 (7%)
Frame = +1
Query: 4609 ELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISN--------KDVEAEEKR 4764
E+ M +++ELE+N+ E AR LE + L E + + DV+ R
Sbjct: 855 EIEKMNQKIKELEENIANEEKARKELESNSTKLLEERNNVFNELEAAKAQLSDVDDRLNR 914
Query: 4765 RGLLK-----QIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL-EVANRLKEEYXX 4926
LK QI +LE L +++ S +KKIEN + L++ + ++ RL++
Sbjct: 915 LSTLKTDVEKQIHELEERLGDQEDRNSDLSRSKKKIENDVENLKKAIADLEIRLQK---- 970
Query: 4927 XXXXXXXXXXEYQIEC--EEARQAKEDIAALLREADRKFRAVEAEREQLR-EANEG---- 5085
E QI +E +Q E+IA L +E + E L+ E ++G
Sbjct: 971 --TDADKQSREQQIRTLQDEMQQQDENIAKLNKEKKHQEEINRKLMEDLQVEEDKGNYSF 1028
Query: 5086 -LMQARKQXXXXXXXXXXXRAKGGGISSEEKRRL--EAKIAQXXXXXXXXQSNCELAIDK 5256
L +Q +G ++KR++ E K+AQ Q + E+ +
Sbjct: 1029 KLKGKLEQSLDDLEDNLEREKRGRNEIEKQKRKIGGELKVAQENMEEIERQRH-EIESNL 1087
Query: 5257 QRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELE----SGAQSRARA 5424
++K + + + ITT L E+ L SL+ R + +I+ELE + QSR++A
Sbjct: 1088 KKK-ESEAQAITTRLEEEQDL-------LGSLKTCQRTTQNRISELEEELENERQSRSKA 1139
Query: 5425 QMAA--LEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANE-QAKEL 5595
+ A L+ +++ L D+L+ +G A ++ E L + E+ +E Q +
Sbjct: 1140 ERAKSDLQRELEELGDRLDEQGGATAAQVEVNKKREAELAKLRRDLEEANMNHENQLAAI 1199
Query: 5596 LEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
+K N L Q+++A+ + + QR+A+DL+ + T MN
Sbjct: 1200 RKKHNDAVAELGDQIEQAQKAKVKLKKTKIQAQRDAEDLVAQIDGETAARMN 1251
Score = 56.2 bits (134), Expect = 9e-06
Identities = 62/344 (18%), Positives = 127/344 (36%), Gaps = 7/344 (2%)
Frame = +1
Query: 2548 DDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIR 2727
++E R+K D +R K K+E D E E LD A Q+ +++ + EL
Sbjct: 1609 ENETRSKADLMRLKK----KLESDINELEIALDHANQANAEAQKNVKRYQDQIRELQQQV 1664
Query: 2728 GRLQTRNQELEYIVNDMRDRL----SXXXXXXXXXXXXRRKQMETVRDXXXXXXX---XX 2886
Q +E+ V+DM + S R + ++ RD
Sbjct: 1665 EMQQRNREEIRENVSDMEKKATLLQSEKEEMSVAMVSSERTRKQSERDANEAHVQCNELS 1724
Query: 2887 XXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAK 3066
K ++ + Y L QL +E +
Sbjct: 1725 AQAESLSSVKKKLETELLAIQADLDETLNEYKASEERYKAASSDAALLAEQLRQEQENSL 1784
Query: 3067 HGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNN 3246
+ + LE+QL E++ L+ A L+ K +A+ ++ EL
Sbjct: 1785 QNDRIRKALESQLKEMQARLDEAEA-------------AALKGGKKVIAKLQSRIREL-- 1829
Query: 3247 QLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRRE 3426
+ EL + RY E + ++T ++++R++Q +DE R++ E R+ K + +
Sbjct: 1830 -----ESELDGEQRRYQETNKSLTKHERRIRELQFQVDEDRKNAERTRDLIEKLQNKLKS 1884
Query: 3427 VVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQ 3558
Q+E+ + + + +Q + +E + + ++ +++
Sbjct: 1885 QKKQIEEAEELANVNLQKFRQIQHQLDDAEERADHAENSLSKMR 1928
>gi|41350446|gb|AAS00505.1| fast skeletal muscle myosin heavy chain
[Siniperca chuatsi]
Length = 1937
Score = 1082 bits (2799), Expect = 0.0
Identities = 633/1888 (33%), Positives = 1048/1888 (54%), Gaps = 14/1888 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V D +E +L G + ++ + VE DT + VT+ +D+ NPPK+DKIEDM +T+L
Sbjct: 39 FVVDADEMYLKGKLVKKEGGKATVE-TDTGKTVTVKEEDIHPRNPPKYDKIEDMVMMTHL 97
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
NE VL+NLK+RY S +IYTYSGLFCVV+NPYK LP+Y ++ ++GKKR E PPHIF+
Sbjct: 98 NEPCVLYNLKERYASWMIYTYSGLFCVVVNPYKWLPVYDAVVVGAYRGKKRIEAPPHIFS 157
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ M +RE+QS+L TGESGAGKT NTK+VIQY A +A K+
Sbjct: 158 ISDNAYQFMHTDRENQSVLITGESGAGKTVNTKRVIQYFATIAAIGAKKA---------- 207
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
+P G LE Q++ ANP+LEA+GN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 208 -EPTPGKMQGSLEDQIVAANPLLEAYGNAKTVRNDNSSRFGKFIRIHFGSTGKLASADIE 266
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRF-LVNRG-ITLPNV 981
YLLEKSRV Q ERS+HIFYQ++ G E E LL + Y + ++++G IT+ ++
Sbjct: 267 TYLLEKSRVTFQLSAERSYHIFYQLMTG-HKPELLEALLITTNPYDYPMISQGEITVKSI 325
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
+DV+EF +T ++ I+GF +E I ++ AV+ GN++F Q+++ +QA V K
Sbjct: 326 NDVEEFIATDTAIDILGFTAEEKMGIYKLTGAVMHHGNMKFKQKQREEQAEPDGTEVADK 385
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+ +LLGL ++ K PR+KVG E V K Q Q AV A+ K+ YE++F W+V RI
Sbjct: 386 ISYLLGLNSADMLKYLCYPRVKVGNEMVTKGQTVPQVNNAVSALCKSVYEKMFLWMVIRI 445
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
++ LD T + +IG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 446 DEMLD-TKQARQFYIGVLDIAGFEIFDYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 504
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGI+W+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA+D +F KL H K
Sbjct: 505 KEGIQWEFIDFGMDLASCIELIEKPMGIFSILEEECMFPKASDTTFKNKLHDQHLGKTKA 564
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P ++++HF++VHYAG VDY+ WL KN DPLN++VV L Q S++ +A ++
Sbjct: 565 FEKPKPGKGKAEAHFSLVHYAGTVDYNITGWLEKNKDPLNDSVVQLYQKSSNKLLAFLYA 624
Query: 1870 DAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHE 2049
A AA + G + + G F+TVS + +E L KLMT LR+T PHFVRC+IPN
Sbjct: 625 SHGAADEAAASGKK---GGKKKGGSFQTVSAVFRENLGKLMTNLRSTHPHFVRCLIPNES 681
Query: 2050 KKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDG 2226
K G + + LV+ QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L VIP+ F+D
Sbjct: 682 KTPGLMENFLVIHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASVIPEGQFMDN 741
Query: 2227 KESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSR 2406
K++ K++ ++D+D Y G +KVFF+ G+L LEE RD KL AL+ QA CRG++ R
Sbjct: 742 KKASEKLLGSIDVDHTQYMFGHTKVFFKAGLLGALEEMRDEKLAALVTMTQALCRGYVMR 801
Query: 2407 RLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRA 2586
+ + N +++ ++NW W +L+ K+KPLL+ T+ E+ +
Sbjct: 802 KEFVKMMERRESIYSIQYNIRSFMNVKNWPWLKLYFKIKPLLKSAETEKELSQMKENYDK 861
Query: 2587 TKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYI 2766
K L +E E+K+ ++ E+ +Q Q+ E EN ++ ++ L +LE
Sbjct: 862 MKTDLATALAKKKELEEKMVSLLQEKNDLQLQVASEVENLSDAEERCEGLIKSKIQLEAK 921
Query: 2767 VNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXX 2946
+ + +RL +RK + + +K +
Sbjct: 922 LKETTERLEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 981
Query: 2947 XXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDL 3126
++ L E++ KAK +LE Q+ +LE L
Sbjct: 982 TEEMASQDESIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSL 1041
Query: 3127 NRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEES 3306
+E++ + +LE+ KRKL +L+ +++ + + ++ + ++ K++ E L++ ++E
Sbjct: 1042 EQEKKLRMDLERAKRKLEGDLKLAQESIMDLENDKQQSDEKIKKKEFETSQLLSKIEDEQ 1101
Query: 3307 ANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT 3486
+ +QK+++++Q I+EL E++E ER AR K E R ++ +LE++ + L++ AT
Sbjct: 1102 SLGAQLQKKIKELQARIEELEEEIEAERAARAKVEKQRADLSRELEEI-SERLEEAGGAT 1160
Query: 3487 MLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQL 3663
Q M++K E E +R +E+ E + K + V EL +QI+ ++ + +L
Sbjct: 1161 AAQIEMNKKREAEFQKLRRDLEEATLQHEATASALRKKQADSVAELGEQIDNLQRVKQKL 1220
Query: 3664 EKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQL 3843
EK++++ E D++ + + ++ +++K + E E+++ E+ + Q
Sbjct: 1221 EKEKSEYKMEIDDLSSNMEAVAKAKGNLEKMCRTLEDQFSELKSKNDETVRQLNDINAQK 1280
Query: 3844 ERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLE 4023
R + E +R EE+E + + R + K A + +
Sbjct: 1281 ARLQTENGEYSRQLEEKEALVSQLTRGKQAFTQQIEEFKRHVEEEVKAKNALAHAVQSAR 1340
Query: 4024 DEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHL 4203
+ + L ++ EE + +A L++ + A + R K E Q+ EEL + + + L
Sbjct: 1341 HDCDLLREQFEEEQEAKAELQRGMSKANSEVAQWRSKYETDAIQRTEELEEAKKKLAQRL 1400
Query: 4204 QKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEER 4374
Q E E + + ++K+++Q E+ED +++E A + +K+Q+ F+ +AE +
Sbjct: 1401 QDAEESIEAVNSKCASLEKTKQRLQGEVEDLMIDVERANALAANLDKKQRNFDKVLAEWK 1460
Query: 4375 VAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKD 4554
++ + + +E R T + + N + + LE R ++LQQE+ D
Sbjct: 1461 QKYEEGQAELEGAQKEARSLSTELFKMKNSYEESLDQLETMKRENKNLQQEISDLTEQIG 1520
Query: 4555 DFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAIS 4734
+ GK++HELEKAK+++E E +++ +EE E L+ E LR+++ +K E DR ++
Sbjct: 1521 ETGKSIHELEKAKKTVETEKTEIQSALEEAEGTLEHEEAKILRVQLELNQIKGEVDRKLA 1580
Query: 4735 NKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKE 4914
KD E E+ +R + + +++ L++E R ++ A+ +KK+E + E+E QL ANR
Sbjct: 1581 EKDEEMEQIKRNSQRVMDSMQSALDSEVRSRNDALRVKKKMEGDLNEMEIQLSHANRQAA 1640
Query: 4915 EYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQ 5094
E + Q+ ++A + +ED+ + +R+ + AE E+LR A E +
Sbjct: 1641 EAQKQLRNVQGQLKDAQLHLDDAVRGQEDMKEQVAMVERRNGLMLAEIEELRVALEQTER 1700
Query: 5095 ARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRK 5265
RK Q K++LEA + Q A +K +K
Sbjct: 1701 GRKVAEQELVDASERVGLLHSQNTSLMNTKKKLEADLVQVQGEVEDSVQEARNAEEKAKK 1760
Query: 5266 AQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEA 5445
A + +L E+ + E K++LE + +D + ++ E E+ A + Q+ LE+
Sbjct: 1761 AITDAAMMAEELKKEQDTSSHLERMKKNLEVTVKDLQHRLDEAENLAMKGGKKQLQKLES 1820
Query: 5446 KVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRN 5625
+V+ LE +++ E + A + R+ E+R+ + T Q E++K+ + ++L++K LK +
Sbjct: 1821 RVRELEAEVDAEQRRGADAVKGVRKYERRVKELTYQTEEDKKNVVRLQDLVDKLQLKVKA 1880
Query: 5626 LRRQLDEAEDEMSRERTKHRNVQREADD 5709
+RQ +EAE++ + ++ R VQ E ++
Sbjct: 1881 YKRQAEEAEEQANTHMSRLRKVQHEMEE 1908
Score = 140 bits (353), Expect = 4e-31
Identities = 191/925 (20%), Positives = 370/925 (39%), Gaps = 37/925 (4%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLA---EKMGKVEELNN 3246
K +++ +++ DL K ELE+ LL E D + +A E + EE
Sbjct: 850 KELSQMKENYDKMKTDLATALAKKKELEEKMVSLLQEKNDLQLQVASEVENLSDAEERCE 909
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
L+K +L+ +L DEE N L K+ R ++ EL++D++ E
Sbjct: 910 GLIKSKIQLEAKLKETTERLEDEEEINAELTAKK-RKLEDECSELKKDIDD-------LE 961
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E + +++ +E A + A +Q ++ +
Sbjct: 962 LTLAKVEKEKHATENKVKNLTEEMASQDESIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1021
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK 3753
+ + K K +QV++L +EQ KK R LE+ + + + + + I L+ + D+
Sbjct: 1022 TLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDLENDKQQSDE 1081
Query: 3754 KRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLAT 3933
K K E ++ + + E +++L QL++ EL R+ E EE A R
Sbjct: 1082 KIKKKEFETSQLLSKI----EDEQSLGAQLQKKIKELQA--RIEELEEEIEAERAARAKV 1135
Query: 3934 AXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQG 4113
RL+ A A Q+E +++K EAE R+
Sbjct: 1136 EKQRADLSRELEEISERLEEAGGATAAQIE------MNKKREAE---------FQKLRRD 1180
Query: 4114 AGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSM 4293
EA + E + + LRKK V L +Q++ + K+++ + K + + E++D S
Sbjct: 1181 LEEATLQHEATASA----LRKKQADSVAELGEQIDNLQRVKQKLEKEKSEYKMEIDDLSS 1236
Query: 4294 ELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDI 4473
+E V + + EK + E Q +E + D ++L D + L E
Sbjct: 1237 NMEAVAKAKGNLEKMCRTLEDQFSELKSK-------NDETVRQLNDINAQKARLQTENGE 1289
Query: 4474 MKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDN 4653
LEE + + L + Q ++F ++V E KAK +L + R + L +
Sbjct: 1290 YSRQLEEKEALVSQLTRGKQAFTQQIEEFKRHVEEEVKAKNALAHAVQSARHDCDLLREQ 1349
Query: 4654 LQIAEDARLRL---------EVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENEL 4806
+ ++A+ L EV K E+D AI + E EE ++ L ++++D E +
Sbjct: 1350 FEEEQEAKAELQRGMSKANSEVAQWRSKYETD-AIQRTE-ELEEAKKKLAQRLQDAEESI 1407
Query: 4807 ENEKRGKSGAVSHRKKIENQIGELEQQLEVANRL-------KEEYXXXXXXXXXXXXEYQ 4965
E + +++++ ++ +L +E AN L + + E Q
Sbjct: 1408 EAVNSKCASLEKTKQRLQGEVEDLMIDVERANALAANLDKKQRNFDKVLAEWKQKYEEGQ 1467
Query: 4966 IECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRA 5145
E E A++ ++ L + + + E ++ N+ L Q
Sbjct: 1468 AELEGAQKEARSLSTELFKMKNSYEESLDQLETMKRENKNLQQEISDLTEQIGET----- 1522
Query: 5146 KGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQ 5325
G I EK + + + ++ L ++ + +VQLE ++R L +
Sbjct: 1523 -GKSIHELEKAKKTVETEKTEIQSALEEAEGTLEHEEAKILRVQLELNQIKGEVDRKLAE 1581
Query: 5326 KTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAAN 5505
K E +E+ R+ + + ++S S R++ AL K
Sbjct: 1582 KDE----EMEQIKRNSQRVMDSMQSALDSEVRSRNDALRVK------------------- 1618
Query: 5506 RAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEA---EDEMSRE-- 5670
+++E LN+ Q R +A++ L + ++ + LD+A +++M +
Sbjct: 1619 ---KKMEGDLNEMEIQLSHANRQAAEAQKQLRNVQGQLKDAQLHLDDAVRGQEDMKEQVA 1675
Query: 5671 RTKHRN--VQREADDLLDANEQLTR 5739
+ RN + E ++L A EQ R
Sbjct: 1676 MVERRNGLMLAEIEELRVALEQTER 1700
Score = 138 bits (348), Expect = 1e-30
Identities = 148/812 (18%), Positives = 329/812 (40%), Gaps = 16/812 (1%)
Frame = +1
Query: 3325 QKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEK------VKGDVLDKVDEAT 3486
+K++ M+ D+++ D+ T K E+ + V EK V +V + D
Sbjct: 849 EKELSQMKENYDKMKTDLATA--LAKKKELEEKMVSLLQEKNDLQLQVASEVENLSDAEE 906
Query: 3487 MLQDLMSRKDEEVNATKRAIEQIQHTME--GKIEEQKAKFSRQVEELHDQIEQHKKQRSQ 3660
+ L+ K + K E+++ E ++ +K K + EL I+ + ++
Sbjct: 907 RCEGLIKSKIQLEAKLKETTERLEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAK 966
Query: 3661 LEKQQNQADQERADMAQEIALLQASRADIDKKRK-IHEAHLMEIQANLAESDEHKRTLID 3837
+EK+++ + + ++ +E+A S A + K++K + EAH + AE D+ TL
Sbjct: 967 VEKEKHATENKVKNLTEEMASQDESIAKLTKEKKALQEAHQQTLDDLQAEEDK-VNTLTK 1025
Query: 3838 QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQ 4017
+ ++D L E+E+ +++R K + + ++
Sbjct: 1026 AKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDLENDKQQSDEKIKK 1085
Query: 4018 LEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVE 4197
E E + LL + E+ + L A L+K+I +EL+ + +E
Sbjct: 1086 KEFETSQLLSKIEDEQSLGAQLQKKI----------------------KELQAR----IE 1119
Query: 4198 HLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERV 4377
L++++E A+ ++ + + + +ELE+ S LE + + KK E++ + R
Sbjct: 1120 ELEEEIEAERAARAKVEKQRADLSRELEEISERLEEAGGATAAQIEMNKKREAEFQKLRR 1179
Query: 4378 AVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDD 4557
+++A L +A + LR ++ DS++ +
Sbjct: 1180 DLEEATLQHEATASALRKKQA-------------------------------DSVA---E 1205
Query: 4558 FGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISN 4737
G+ + L++ K+ LE E ++ ++++++L N++ A+ LE + R + +
Sbjct: 1206 LGEQIDNLQRVKQKLEKEKSEYKMEIDDLSSNMEAVAKAKGNLE--------KMCRTLED 1257
Query: 4738 KDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEE 4917
+ E + K ++Q+ D+ + + +++ + GE +QLE L +
Sbjct: 1258 QFSELKSKNDETVRQLNDIN--------------AQKARLQTENGEYSRQLEEKEALVSQ 1303
Query: 4918 YXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA----DRKFRAVEAEREQLREANEG 5085
E++ EE +AK +A ++ A D E E+E E G
Sbjct: 1304 LTRGKQAFTQQIEEFKRHVEEEVKAKNALAHAVQSARHDCDLLREQFEEEQEAKAELQRG 1363
Query: 5086 LMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRK 5265
+ +A + + E K++L ++ S C +++
Sbjct: 1364 MSKANSEVAQWRSKYETDAIQRTEELEEAKKKLAQRLQDAEESIEAVNSKCASLEKTKQR 1423
Query: 5266 AQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES---GAQSRARAQMAA 5436
Q ++E + D+ L + ++++ ++ ++K K E ++ GAQ AR+
Sbjct: 1424 LQGEVEDLMIDVERANALAANLDKKQRNFDKVLAEWKQKYEEGQAELEGAQKEARSLSTE 1483
Query: 5437 LEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLK 5616
L E+ L+ + R + L++ ++D T+Q + ++ + ++ + +
Sbjct: 1484 LFKMKNSYEESLD----QLETMKRENKNLQQEISDLTEQIGETGKSIHELEKAKKTVETE 1539
Query: 5617 NRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
++ L+EAE + E K VQ E + +
Sbjct: 1540 KTEIQSALEEAEGTLEHEEAKILRVQLELNQI 1571
Score = 120 bits (302), Expect = 3e-25
Identities = 169/890 (18%), Positives = 359/890 (39%), Gaps = 124/890 (13%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ +E ++ +E+D +++++K+ + E + + +++ E A+L LQ
Sbjct: 1056 RKLEGDLKLAQESIMDLENDKQQSDEKIKKKEFETSQLLSKIEDEQSLGAQLQKKIKELQ 1115
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + R +++E + + +
Sbjct: 1116 ARIEELEEEIEAER----AARAKVEKQRADLSRELEEISERLEEAGGATAAQIEMNKKRE 1171
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K +
Sbjct: 1172 AEFQKLRRDLEEATLQHEATASALRKKQADSVAELG---EQIDNLQRVKQKLEKEKSEYK 1228
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K LE+ R L + + K E + ++ ++N Q + E
Sbjct: 1229 MEIDDLSSNMEAVAKAKGNLEKMCRTLEDQFSELKSKNDETVRQLNDINAQKARLQTENG 1288
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ +E+ A V+ + + + I+E + +E E A+N + + ++
Sbjct: 1289 EYSRQLEEKEALVSQLTRGKQAFTQQIEEFKRHVEEEVKAKNALAHAVQSARHDCDLLRE 1348
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
++ + LQ MS+ + EV +K + IQ T E +EE K K ++++++ +
Sbjct: 1349 QFEEEQEAKAELQRGMSKANSEVAQWRSKYETDAIQRTEE--LEEAKKKLAQRLQDAEES 1406
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEI------- 3789
IE + + LEK + + E D+ ++ A A++DKK++ + L E
Sbjct: 1407 IEAVNSKCASLEKTKQRLQGEVEDLMIDVERANALAANLDKKQRNFDKVLAEWKQKYEEG 1466
Query: 3790 QANLAESDEHKRTLIDQLERSR----DELDHLNRVREEEEHAFANMQRRLATAXXXXXXX 3957
QA L + + R+L +L + + + LD L ++ E + N+Q+ ++
Sbjct: 1467 QAELEGAQKEARSLSTELFKMKNSYEESLDQLETMKRENK----NLQQEISDLTEQIGE- 1521
Query: 3958 XXXXXXXTRLKIANINRARQ-LEDEKNALLDEKEEAEGLRAHLEKEIHAAR----QGAGE 4122
T I + +A++ +E EK + EEAEG H E +I + Q GE
Sbjct: 1522 -------TGKSIHELEKAKKTVETEKTEIQSALEEAEGTLEHEEAKILRVQLELNQIKGE 1574
Query: 4123 ARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
RK E ++++E++++ + R ++ +Q L+ ++ L+ KKK++ +L + ++L
Sbjct: 1575 VDRKLAEK-DEEMEQIKRNSQRVMDSMQSALDSEVRSRNDALRVKKKMEGDLNEMEIQLS 1633
Query: 4303 --------------NVRASHRDS---------------------EKRQKKFESQMAEERV 4377
NV+ +D+ E+R +++ E RV
Sbjct: 1634 HANRQAAEAQKQLRNVQGQLKDAQLHLDDAVRGQEDMKEQVAMVERRNGLMLAEIEELRV 1693
Query: 4378 AVQKALLDRDAMSQELRDRETRV-------LSLLN-----EVDIMKEHLEESDRVR--RS 4515
A+++ R QEL D RV SL+N E D+++ E D V+ R+
Sbjct: 1694 ALEQTERGRKVAEQELVDASERVGLLHSQNTSLMNTKKKLEADLVQVQGEVEDSVQEARN 1753
Query: 4516 LQQELQDSISNKDDFGKNVHE-------LEKAKRSLEAELNDMRVQMEELED-------- 4650
+++ + +I++ + + + LE+ K++LE + D++ +++E E+
Sbjct: 1754 AEEKAKKAITDAAMMAEELKKEQDTSSHLERMKKNLEVTVKDLQHRLDEAENLAMKGGKK 1813
Query: 4651 ----------NLQIAEDARLRL----------------EVTNQALKSESD---------- 4722
L+ DA R E+T Q + + +
Sbjct: 1814 QLQKLESRVRELEAEVDAEQRRGADAVKGVRKYERRVKELTYQTEEDKKNVVRLQDLVDK 1873
Query: 4723 -----RAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKI 4857
+A + EAEE+ + ++R +++E+E + A S K+
Sbjct: 1874 LQLKVKAYKRQAEEAEEQANTHMSRLRKVQHEMEEAQERADIAESQVNKL 1923
Score = 91.7 bits (226), Expect = 2e-16
Identities = 89/438 (20%), Positives = 190/438 (43%), Gaps = 23/438 (5%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L Q+ E + ++ + K +E K ++ + LE+++ L + K+ + +L + E
Sbjct: 1515 LTEQIGETGKSIHELEKAKKTVETEKTEIQSALEEAEGTLEHEEAKILRVQLELNQIKGE 1574
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ +L DEE M++ R+ Q +D ++ +++E +RN A ++++ L ++
Sbjct: 1575 VDRKLAEKDEE------MEQIKRNSQRVMDSMQSALDSEVRSRNDALRVKKKMEGDLNEM 1628
Query: 3451 KGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
+ + +A Q + ++ + ++ E ++EQ A R+ + +
Sbjct: 1629 EIQLSHANRQAAEAQKQLRNVQGQLKDAQLHLDDAVRGQED-MKEQVAMVERRNGLMLAE 1687
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAES 3810
IE+ + Q E+ + A+QE D ++ + LL + + +K EA L+++Q + +S
Sbjct: 1688 IEELRVALEQTERGRKVAEQELVDASERVGLLHSQNTSLMNTKKKLEADLVQVQGEVEDS 1747
Query: 3811 DEHKRT--------------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXX 3948
+ R + ++L++ +D HL R+++ E ++Q RL A
Sbjct: 1748 VQEARNAEEKAKKAITDAAMMAEELKKEQDTSSHLERMKKNLEVTVKDLQHRLDEAENLA 1807
Query: 3949 XXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEAR 4128
+R R+LE E +A E+ G A K + + E
Sbjct: 1808 MKGGKKQLQKLE------SRVRELEAEVDA-----EQRRG--ADAVKGVRKYERRVKELT 1854
Query: 4129 RKAEESVNQ--QLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELED------ 4284
+ EE +L++L K V+ ++Q EE+E + +K+Q E+E+
Sbjct: 1855 YQTEEDKKNVVRLQDLVDKLQLKVKAYKRQAEEAEEQANTHMSRLRKVQHEMEEAQERAD 1914
Query: 4285 -SSMELENVRASHRDSEK 4335
+ ++ +RA RD+ K
Sbjct: 1915 IAESQVNKLRAKSRDAGK 1932
Score = 36.2 bits (82), Expect = 9.9
Identities = 33/160 (20%), Positives = 71/160 (43%), Gaps = 16/160 (10%)
Frame = +1
Query: 5311 RTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQE 5490
+ L + E EK+ L + +Y T+L + + + + + + QL V +
Sbjct: 840 KPLLKSAETEKE-LSQMKENYDKMKTDLATALAKKKELEEKMVSLLQEKNDLQLQVASEV 898
Query: 5491 KTAANRAAR---------RLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLD 5643
+ ++ R +LE +L +TT++ EDE+ N + K + L++ +D
Sbjct: 899 ENLSDAEERCEGLIKSKIQLEAKLKETTERLEDEEEINAELTAKKRKLEDECSELKKDID 958
Query: 5644 EAEDEMSR-ERTKH------RNVQREADDLLDANEQLTRE 5742
+ E +++ E+ KH +N+ E ++ +LT+E
Sbjct: 959 DLELTLAKVEKEKHATENKVKNLTEEMASQDESIAKLTKE 998
>gi|39590394|emb|CAE66133.1| Hypothetical protein CBG11357
[Caenorhabditis briggsae]
Length = 1904
Score = 1082 bits (2797), Expect = 0.0
Identities = 642/1908 (33%), Positives = 1034/1908 (53%), Gaps = 22/1908 (1%)
Frame = +1
Query: 52 ATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKF 231
AT + +K WV D EGF+ IK D V+V + + TI +DD Q+ NPPK+
Sbjct: 4 ATTKKFDSKKNVWVADPEEGFIAAEIKSSKGDTVVV-VTSKGVEKTIKKDDAQQMNPPKY 62
Query: 232 DKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKG 411
+K EDM+ LT+LN+ASVLHNL+ RYYS +IYTYSGLFCVVINPYK+LPIYSE + + + G
Sbjct: 63 EKTEDMANLTFLNDASVLHNLRQRYYSMMIYTYSGLFCVVINPYKRLPIYSESVCQMYLG 122
Query: 412 KKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRN 591
K+R+EMPPH+FA++D AYR+M ++E+QS+L TGESGAGKTENTKKVI Y A V
Sbjct: 123 KRRNEMPPHLFAVSDEAYRNMTNDKENQSMLITGESGAGKTENTKKVISYFAMVG----- 177
Query: 592 KSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINF 771
A+QQ+ +K LE Q++Q NP+LEAFGN+KTV+N+NSSRFGKFIRI+F
Sbjct: 178 -----ASQQSKKEKSKKDKAQVSLEDQIVQTNPVLEAFGNAKTVRNNNSSRFGKFIRIHF 232
Query: 772 DMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGC--SAKEKSEYLLEGVDNYR 945
+ G ++GA+IE YLLEKSRV++QA ERS+HIFYQI +EK +L + Y
Sbjct: 233 NQGGKVAGADIEHYLLEKSRVIKQAPGERSYHIFYQIYSDAVKGLREKL-FLTRPIKEYT 291
Query: 946 FLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSD 1125
F+ +T+ VDD +E T + IM F E S + + + ++ +G L+F Q + +
Sbjct: 292 FVSQAEVTIDGVDDKEEMLITDEAFDIMKFTATEKSELFAITAGIMHMGELKFKQRPREE 351
Query: 1126 QAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKAS 1305
QA L+D + + C L + + A L+PR+KVG E+VNK QN +Q +AV A+AKA
Sbjct: 352 QAELEDGKEGELACKLYCVEAEKFVGALLKPRVKVGTEWVNKGQNLDQVNWAVGALAKAL 411
Query: 1306 YERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFN 1485
+ R+FKWL+TR NK+LD FIG+LDIAGFEIFD+NSFEQ+ IN+ NEKLQQ FN
Sbjct: 412 FARMFKWLITRCNKTLDAQDLSRDFFIGVLDIAGFEIFDLNSFEQLWINFVNEKLQQFFN 471
Query: 1486 NTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVE 1665
+ MF+LEQEEY+REGI+W+FIDFGLDLQ I+LIEKP+G++++LDEEC+ PKA D +
Sbjct: 472 HHMFVLEQEEYKREGIQWEFIDFGLDLQACIELIEKPLGIVSMLDEECIVPKATDLTLAS 531
Query: 1666 KLQKTH-NKHPKFIVP----DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLM 1830
KL H KHP F P ++++H A+VHYAG V Y+ WL KN DPLN+ V ++
Sbjct: 532 KLNDQHLGKHPNFQKPRPPKGKQAEAHLAIVHYAGTVRYNVKGWLEKNKDPLNDTAVTVL 591
Query: 1831 Q-NSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKG---MFRTVSQLHKEQLTKLMTT 1998
+ N + +A +W D AA E + +KG F TVS +++E L KLM
Sbjct: 592 KGNKGNQLMADLWADYSTQEDVAAAAKEGKKAVGKKKGKSASFMTVSMMYRESLNKLMHM 651
Query: 1999 LRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHR 2178
L T PHF+RCIIPN KKSG I++NLVL QL CNGVLEGIRICR+GFPNR+PF +F+ R
Sbjct: 652 LHQTHPHFIRCIIPNEMKKSGMIDANLVLNQLTCNGVLEGIRICRKGFPNRMPFLDFKQR 711
Query: 2179 YEILTPDVIPKNFIDGKESVRKMITALDIDTNL----YRIGQSKVFFRTGVLAHLEEERD 2346
Y +L D K+ D K++ K+ AL D +L ++ G +KVFF+ GVLAHLEE RD
Sbjct: 712 YAVLAADA-AKSGKDPKDAGEKISAALIKDGSLKPEEFQCGLTKVFFKAGVLAHLEELRD 770
Query: 2347 LKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKP 2526
L ++ FQ CR +L++ Y N A+ LR+W W++LF +VKP
Sbjct: 771 EALGKIMAKFQCACRHYLAQCEYKRKLDQKVGLIVLQRNIRAWCTLRSWAWFKLFGRVKP 830
Query: 2527 LLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENS 2706
L++ ++ ++E A + + + +E + E ++ E + ++ E+ + QL+QE ++S
Sbjct: 831 LIKGSKKNEEFEALEKKFKVLEEEKTQEERKRKDMEAENARLEAEKQALLIQLEQERDSS 890
Query: 2707 AELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXX 2886
AE ++ +L ++ +LE + ++ D+L ++K +
Sbjct: 891 AEGEERSAKLLSQKADLEKQMANLNDQLCDEEEKNAALVKQKKKIEQDNEGLKKTVSDLE 950
Query: 2887 XXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAK 3066
+K + D + L + E++
Sbjct: 951 TTIKKQESEKQSKDHQIRSLQDEIQSQDEVISKLNKEKKHQEEVNRKLLEDIQAEEDKVN 1010
Query: 3067 HGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNN 3246
H K K +LE+ L ELE L RE++ + + E+ KRK+ EL+ +A+++ +EELN
Sbjct: 1011 HLNKTKAKLESTLDELEDTLEREKRGRQDCEKQKRKVEGELK-----IAQEL--IEELNR 1063
Query: 3247 QLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRRE 3426
++++E A +K +MQ ++EL + ++ A ++
Sbjct: 1064 H-------------KHEQEQA-----EKARNEMQLELEELGDRLDEAGGATQAQIELNKK 1105
Query: 3427 VVAQLEKVKGDVLD-KVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFS 3603
A+L K++ D+ D ++ T + L + ++ V ++ +Q M GK+E +K
Sbjct: 1106 REAELAKLRQDLEDAAINAETSMAALRKKHNDAVAELSDQLDTVQ-KMRGKLEREKNDKQ 1164
Query: 3604 RQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLM 3783
R+V+EL + KQR E+ Q + + D+ + ++ R I E +
Sbjct: 1165 REVDELQQSADVEAKQRQNCERMAKQLEAQLTDITLK---------SDEQARLIQE---L 1212
Query: 3784 EIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXX 3963
+ N S+ H L QLE + +L LNR+++++ + ++R L
Sbjct: 1213 TMSKNKIHSENH--DLNRQLEDAESQLSALNRIKQQQHNQMEELKRTL------------ 1258
Query: 3964 XXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAE- 4140
TR + + ++ + E L + EE + + +++++ A + R K E
Sbjct: 1259 --DQETRERQSLHSQVSNYQLECEQLRESLEEEQDAKTDVQRQLSKANSEIQQWRAKFEG 1316
Query: 4141 ESVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRA 4314
E V ++LEE R+K V+ +Q+QLE + + ++K+++ +LED+ ++ + +
Sbjct: 1317 EGVTRAEELEETRRKLTHKVQEMQEQLENANQKIGTLEKTKQRLAHDLEDAQVDADRANS 1376
Query: 4315 SHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEE 4494
EK+QK F+ + E R + + + + +E R T L N+++ E E
Sbjct: 1377 IASSLEKKQKGFDKVLEEWRRKCEALVAEVEQSQRETRAAATETFRLRNQLEESGEQTEA 1436
Query: 4495 SDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDA 4674
R ++L QEL+D + GK+VH+L+K +R LE E +++ ++E E L+ E
Sbjct: 1437 VKRENKALAQELKDIADQLGEGGKSVHDLQKLRRRLEIEKEELQQALDEAECALEAEEAK 1496
Query: 4675 RLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKK 4854
+R ++ ++SE ++ + KD E E R+ + I ++ LE E RG++ + +KK
Sbjct: 1497 VMRAQIEVSQIRSEIEKRLQEKDEEFENTRKNHSRTIESMQVSLETESRGRAELLKTKKK 1556
Query: 4855 IENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRK 5034
+E + ELE L+ +N+L + E Q++ EE +++ ++ A+R+
Sbjct: 1557 LEGDVNELEIALDHSNKLNVDGQKSIKKLQDTIRELQLQVEEEQRSLNEVRDHANLAERR 1616
Query: 5035 FRAVEAEREQLREANEGLMQARKQX---XXXXXXXXXXRAKGGGISSEEKRRLEAKIAQX 5205
+ ++ E+E L E ++R+Q + + KR++E +
Sbjct: 1617 SQVLQQEKEDLAIIYEQSERSRRQAELELAEVKDSVNELSNSNSLLLATKRKVEGDLQHL 1676
Query: 5206 XXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKI 5385
S+ +++ DK +KA + ++ +L E+ + K++LE +D + ++
Sbjct: 1677 QSEVEEALSDAKVSDDKAKKAIMDASKLADELRSEQEHASNLDKSKRALESQVKDLQMRL 1736
Query: 5386 TELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDE 5565
E E+ + Q+A L+ ++ LE +L E + + R +++ + Q +++
Sbjct: 1737 DEAEAAGIKGGKRQLAKLDMRIHELETELEGESRRHGETQKVLRNKDRKCRELQFQVDED 1796
Query: 5566 KRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
K++ E+ +L+EK K + +RQ+++AE S K+R +Q +D
Sbjct: 1797 KKSTERMYDLIEKLQQKIKTYKRQIEDAESLASANLAKYRQLQHVVED 1844
Score = 89.7 bits (221), Expect = 8e-16
Identities = 109/533 (20%), Positives = 220/533 (40%), Gaps = 10/533 (1%)
Frame = +1
Query: 4174 KKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFE 4353
KKN + E L+K+ + E +E+ + +K+ E E++ +E E + ++R E
Sbjct: 836 KKN-EEFEALEKKFKVLE--EEKTQEERKRKDMEAENARLEAEKQALLIQLEQERDSSAE 892
Query: 4354 SQMAEERVAVQKALLDRDA--MSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQE 4527
+ ++ QKA L++ ++ +L D E + +L+ + ++ ++Q+
Sbjct: 893 GEERSAKLLSQKADLEKQMANLNDQLCDEEEKNAALVKQ--------------KKKIEQD 938
Query: 4528 LQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQAL 4707
+ K V +LE + E+E Q+ L+D +Q ++ +L +
Sbjct: 939 -------NEGLKKTVSDLETTIKKQESEKQSKDHQIRSLQDEIQSQDEVISKLNKEKKHQ 991
Query: 4708 KSESDRAISNKDVEAEEKRRGLLKQIR--------DLENELENEKRGKSGAVSHRKKIEN 4863
+ + + + +D++AEE + L + + +LE+ LE EKRG+ ++K+E
Sbjct: 992 EEVNRKLL--EDIQAEEDKVNHLNKTKAKLESTLDELEDTLEREKRGRQDCEKQKRKVEG 1049
Query: 4864 QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRA 5043
++ ++ +E NR K E E+A +A+ ++ L E
Sbjct: 1050 ELKIAQELIEELNRHKH------------------EQEQAEKARNEMQLELEELG----- 1086
Query: 5044 VEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXX 5223
++L EA G QA+ E ++ EA++A+
Sbjct: 1087 -----DRLDEAG-GATQAQ---------------------IELNKKREAELAKLRQDLED 1119
Query: 5224 XQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESG 5403
N E ++ RK +LS + QK + LER D + ++ EL+
Sbjct: 1120 AAINAETSMAALRKKH---NDAVAELSDQLDTVQKMRGK---LEREKNDKQREVDELQQS 1173
Query: 5404 AQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQ 5583
A +VE +++ R A++LE +L D T + +++ R ++
Sbjct: 1174 A----------------------DVEAKQRQNCERMAKQLEAQLTDITLKSDEQARLIQE 1211
Query: 5584 AKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
K + +N +L RQL++AE ++S + + ++L +Q TRE
Sbjct: 1212 LTMSKNKIHSENHDLNRQLEDAESQLSALNRIKQQQHNQMEELKRTLDQETRE 1264
Score = 64.7 bits (156), Expect = 3e-08
Identities = 94/462 (20%), Positives = 192/462 (41%), Gaps = 39/462 (8%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLA-ELEDSKDHLAE---KMGKVEELNNQLM 3255
RL NQL E + ++E + + K LA EL+D D L E + +++L +L
Sbjct: 1422 RLRNQLEESGE--------QTEAVKRENKALAQELKDIADQLGEGGKSVHDLQKLRRRLE 1473
Query: 3256 KRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKA-EMTRREVV 3432
EELQ L DE + + ++ Q + ++R ++E +++ E TR+
Sbjct: 1474 IEKEELQQAL---DEAECALEAEEAKVMRAQIEVSQIRSEIEKRLQEKDEEFENTRKNHS 1530
Query: 3433 AQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKA--KFSR 3606
+E ++ + + L + + +VN + A++ H+ + ++ QK+ K
Sbjct: 1531 RTIESMQVSLETESRGRAELLKTKKKLEGDVNELEIALD---HSNKLNVDGQKSIKKLQD 1587
Query: 3607 QVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME 3786
+ EL Q+E+ ++ +++ N A++ + QE L ++ R+ E L E
Sbjct: 1588 TIRELQLQVEEEQRSLNEVRDHANLAERRSQVLQQEKEDLAIIYEQSERSRRQAELELAE 1647
Query: 3787 IQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXX 3966
++ ++ E L+ + +L HL EE + A + A
Sbjct: 1648 VKDSVNELSNSNSLLLATKRKVEGDLQHLQS-EVEEALSDAKVSDDKAKKAIMDASKLAD 1706
Query: 3967 XXXXTRLKIANINRA-RQLEDEKNALLDEKEEAE--GLR------AHLEKEIHAAR-QGA 4116
+ +N++++ R LE + L +EAE G++ A L+ IH +
Sbjct: 1707 ELRSEQEHASNLDKSKRALESQVKDLQMRLDEAEAAGIKGGKRQLAKLDMRIHELETELE 1766
Query: 4117 GEARRKAE----------------------ESVNQQLEELRKKNLRDVEHLQKQLEESEV 4230
GE+RR E + +++ +L +K + ++ ++Q+E++E
Sbjct: 1767 GESRRHGETQKVLRNKDRKCRELQFQVDEDKKSTERMYDLIEKLQQKIKTYKRQIEDAES 1826
Query: 4231 AKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFES 4356
L +++Q +ED+ E A+ +K + K S
Sbjct: 1827 LASANLAKYRQLQHVVEDAQ---ERADAAENALQKMRLKGRS 1865
Score = 53.9 bits (128), Expect = 5e-05
Identities = 82/402 (20%), Positives = 152/402 (37%), Gaps = 11/402 (2%)
Frame = +1
Query: 4579 LEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEE 4758
LEK + LE E + +++E AE+ARL E ++ E +R + E EE
Sbjct: 844 LEKKFKVLEEEKTQEERKRKDME-----AENARLEAEKQALLIQLEQER---DSSAEGEE 895
Query: 4759 KRRGLLKQIRDLENELEN-------EKRGKSGAVSHRKKIENQIGELEQQL-EVANRLKE 4914
+ LL Q DLE ++ N E+ + V +KKIE L++ + ++ +K+
Sbjct: 896 RSAKLLSQKADLEKQMANLNDQLCDEEEKNAALVKQKKKIEQDNEGLKKTVSDLETTIKK 955
Query: 4915 EYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQ 5094
+ E Q + + R +++I + D + E++ E N L++
Sbjct: 956 Q-----------ESEKQSKDHQIRSLQDEI----QSQDEVISKLNKEKKHQEEVNRKLLE 1000
Query: 5095 ARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQV 5274
I +EE + + K +
Sbjct: 1001 --------------------DIQAEEDKVNHLNKTKA-------------------KLES 1021
Query: 5275 QLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAA--LEAK 5448
L+++ L E+ Q E +K+ +E + + I EL + +A+ A ++ +
Sbjct: 1022 TLDELEDTLEREKRGRQDCEKQKRKVEGELKIAQELIEELNRHKHEQEQAEKARNEMQLE 1081
Query: 5449 VQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEK-RANEQAKELLEKSNLKNRN 5625
++ L D+L+ G A ++ E L Q ED A L +K N
Sbjct: 1082 LEELGDRLDEAGGATQAQIELNKKREAELAKLRQDLEDAAINAETSMAALRKKHNDAVAE 1141
Query: 5626 LRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
L QLD + + + + QRE D+L + + ++ N
Sbjct: 1142 LSDQLDTVQKMRGKLEREKNDKQREVDELQQSADVEAKQRQN 1183
Score = 37.4 bits (85), Expect = 4.4
Identities = 24/110 (21%), Positives = 49/110 (43%)
Frame = +1
Query: 5410 SRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAK 5589
S+ + ALE K + LE++ E +++ RLE Q E E+ ++ + +
Sbjct: 835 SKKNEEFEALEKKFKVLEEEKTQEERKRKDMEAENARLEAEKQALLIQLEQERDSSAEGE 894
Query: 5590 ELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTR 5739
E K + +L +Q+ D++ E K+ + ++ + NE L +
Sbjct: 895 ERSAKLLSQKADLEKQMANLNDQLCDEEEKNAALVKQKKKIEQDNEGLKK 944
>gi|11384448|pir||S02771 myosin heavy chain A [similarity] -
Caenorhabditis elegans
Length = 1992
Score = 1082 bits (2797), Expect = 0.0
Identities = 644/1963 (32%), Positives = 1058/1963 (53%), Gaps = 51/1963 (2%)
Frame = +1
Query: 16 YLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTIS 195
+L + R A A A + +K CW+PD +GF+ I+ T ++V V V Q+T+
Sbjct: 16 FLGISREARAATAA-RPFDSKKNCWIPDPEDGFVAAEIQSTTGEQVTVVTVK-GNQITVK 73
Query: 196 RDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIY----------------- 324
+D Q+ NPPKFDK EDM+ LT+LNEASVL NLKDRY +IY
Sbjct: 74 KDQCQEMNPPKFDKTEDMANLTFLNEASVLGNLKDRYKDLMIYVRKLKLFKKKINTIQKL 133
Query: 325 ------TYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQER 486
TYSGLFCVVINPYK+LPIYSE +I+ F GK+R+EMPPH+FA++D AYR+M+Q++
Sbjct: 134 NRLNFQTYSGLFCVVINPYKRLPIYSESVIKHFMGKRRNEMPPHLFAVSDEAYRNMVQDK 193
Query: 487 EDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELE 666
E+QS+L TGESGAGKTENTKKVI Y A + GAT+ S A G LE
Sbjct: 194 ENQSMLITGESGAGKTENTKKVISYFA-IVGATQAASGKEAKDGK---------KGGTLE 243
Query: 667 HQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQA 846
Q++Q NP+LEAFGN+KTV+N+NSSRFGKFIR +F SG ++G +IE YLLEKSRV+RQA
Sbjct: 244 EQIVQTNPVLEAFGNAKTVRNNNSSRFGKFIRTHFSGSGKLAGGDIEHYLLEKSRVVRQA 303
Query: 847 QDERSFHIFYQILRGCSAKEKSEYLLEG-VDNYRFLVNRGITLPNVDDVQEFHSTINSMR 1023
ER +HIFYQI+ G + + L + Y F +T+ +DD +E T +
Sbjct: 304 PGERCYHIFYQIMSGNDPSLRGKLKLSNDITYYHFCSQAELTIEGMDDKEEMRLTQEAFD 363
Query: 1024 IMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQK 1203
IMGF D+E + R + ++ +G ++F Q + +QA + +LG+ E K
Sbjct: 364 IMGFEDNETMDLYRSTAGIMHMGEMKFKQRPREEQAEPDGEEDALNAAAMLGIQAEEFLK 423
Query: 1204 AFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASF 1383
A +PR++VG E+VNK QN EQ +AV +AKA Y R+FKW++TR NK+LD + F
Sbjct: 424 ALTKPRVRVGTEWVNKGQNLEQVNWAVSGLAKAIYARMFKWIITRCNKTLDAKEIERKHF 483
Query: 1384 IGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLD 1563
IG+LDIAGFEIFD+NSFEQ+ IN+ NE+LQQ FN+ MF+LEQEEY+REGI W FIDFGLD
Sbjct: 484 IGVLDIAGFEIFDLNSFEQLWINFVNERLQQFFNHHMFVLEQEEYKREGIAWTFIDFGLD 543
Query: 1564 LQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPKFIVP----DMRSKS 1728
LQ I+LIEKP+G++++LDEEC+ PKA D ++ +KL H KHP F P + +
Sbjct: 544 LQACIELIEKPLGIISILDEECIVPKATDMTYAQKLLDQHLGKHPNFQKPKPPKGKQGDA 603
Query: 1729 HFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTD-PFVAGIWKD--AEFAGICAA 1899
HFA+VHYAG V Y+A +L KN DPLN+ V L+++STD + IW+D + AA
Sbjct: 604 HFAIVHYAGTVRYNATNFLEKNKDPLNDTAVALLKHSTDNSLMLDIWQDYQTQEEAAEAA 663
Query: 1900 EMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNL 2079
+ +TA G R + F TVS +++E L LM L T PHF+RCIIPN +K SG I+S L
Sbjct: 664 KAGQTAGGKRGKSSSFATVSMIYRESLNNLMNMLYQTHPHFIRCIIPNEKKASGVIDSAL 723
Query: 2080 VLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITAL 2259
VL QL CNGVLEGIRICR+GFPNR+ + +F+HRY IL D ++ D K++ ++ +
Sbjct: 724 VLNQLTCNGVLEGIRICRKGFPNRMLYPDFKHRYAILAADAAKES--DPKKASVGILDKI 781
Query: 2260 DIDTNL----YRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXX 2427
+D NL +++G++K+FF+ GVLA LE+ RD L+ ++ FQ++ R +L++
Sbjct: 782 SVDGNLTDEEFKVGETKIFFKAGVLAKLEDLRDEILSRIVTMFQSRIRSYLAKAEVRRRY 841
Query: 2428 XXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLK 2607
N A+ LR W+W++LF KVKP+L+ + + + +++ +E + +
Sbjct: 842 EQQTGLLVVQRNVRAWCTLRTWEWFKLFGKVKPMLKAGKEQEAMGELAVKIQKLEEAVQR 901
Query: 2608 MEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDR 2787
E + E ++ ++ E+ + L+ E N A+ ++ +L LE ++D+ +
Sbjct: 902 GEIARSQLESQVADLVEEKNALFLSLETEKANLADAEERNEKLNQLKATLESKLSDITGQ 961
Query: 2788 LSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXX 2967
L ++K + + D +K + D
Sbjct: 962 LEDMQERNEDLARQKKKTDQELSDTKKHVQDLELSLRKAEQEKQSRDHNIRSLQDEMANQ 1021
Query: 2968 QDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYK 3147
+A L L E++ H K + +LE Q+ ELE++++RE++ +
Sbjct: 1022 DEAVAKLNKEKKHQEESNRKLNEDLQSEEDKVNHLEKIRNKLEQQMDELEENIDREKRSR 1081
Query: 3148 SELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQ 3327
++E+ KRK+ +L+ +++++ E + ++ L +++E+L H + E ++ + +Q
Sbjct: 1082 GDIEKAKRKVEGDLKVAQENIDEITKQKHDVETTLKRKEEDLHHTNAKLAENNSIIAKLQ 1141
Query: 3328 KQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ-DLM 3504
+ ++++ EL E++E ERN+R K++ +R E +LE++ + L++ AT Q +
Sbjct: 1142 RLIKELTARNAELEEELEAERNSRQKSDRSRSEAERELEELT-ERLEQQGGATAAQLEAN 1200
Query: 3505 SRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIE--QHKKQRSQLEKQQN 3678
+++ E+ +R E+ E I + + V EL +Q+E Q K +S+ EK +
Sbjct: 1201 KKREAEIAKLRREKEEDSLNHETAISSLRKRHGDSVAELTEQLETLQKLKAKSEAEKSKL 1260
Query: 3679 QADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRD 3858
Q D E + A + + SR D++K K E E+Q E + R +
Sbjct: 1261 QRDLEESQHATDSEV--RSRQDLEKALKTIEVQYSELQTKADEQSRQLQDFAALKNRLNN 1318
Query: 3859 ELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNA 4038
E LNR EE ++ ++ R +T +R + A A+ LE E
Sbjct: 1319 ENSDLNRSLEEMDNQLNSLHRLKSTLQSQLDETRRNYDEESRERQALAATAKNLEHENTI 1378
Query: 4039 LLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLE 4218
L + +E +A L ++I + + + + +LEE+ +Q+ +
Sbjct: 1379 LREHLDEEAESKADLTRQISKLNAEIQQWKARFDSEGLNKLEEIEAAKKALQLKVQELTD 1438
Query: 4219 ESEVAKERILQSKK---KIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQK 4389
+E +I +K K+ Q+L+D+ ++E A EK +++FES +AE +
Sbjct: 1439 TNEGLFAKIASQEKVRFKLMQDLDDAQSDVEKAAAQVAFYEKHRRQFESIIAEWKKKTDD 1498
Query: 4390 ALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKN 4569
+ DA ++ R T + D + E+L+ + R +SL QE++D + G++
Sbjct: 1499 LSSELDAAQRDNRQLSTDLFKAKTANDELAEYLDSTRRENKSLAQEVKDLTDQLGEGGRS 1558
Query: 4570 VHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVE 4749
V EL+K R LE E +++ ++E E L+ E LR ++ ++SE ++ I K+ E
Sbjct: 1559 VAELQKIVRKLEVEKEELQKALDEAEAALEAEEAKVLRAQIEVSQIRSEIEKRIQEKEEE 1618
Query: 4750 AEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXX 4929
E RR + + ++ LE E + K A+ +KK+E+ I +LE L+ ANR +
Sbjct: 1619 FENTRRNHQRALESMQATLEAETKQKEEALRIKKKLESDINDLEIALDHANRAYADAQKT 1678
Query: 4930 XXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQX 5109
E Q + EE ++ K++I ++++ +++E+++L + E +AR+
Sbjct: 1679 IKKYMETVQELQFQIEEEQRQKDEIREQFLASEKRNAILQSEKDELAQQAEAAERARRN- 1737
Query: 5110 XXXXXXXXXXRAKGGGISSE------EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQ 5271
R + +++ ++R+LE ++ + + A+++ +KA
Sbjct: 1738 --AEAECIELREQNNDLNAHVSALTGQRRKLEGELLAAHAELEEIANELKNAVEQGQKAS 1795
Query: 5272 VQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKV 5451
++ +L E+ + E ++ LE ++ + ++ + E+ A + +A LEA++
Sbjct: 1796 ADAARLAEELRQEQEHSMHIERIRKGLELQIKEMQIRLDDAENAALKGGKKIIAQLEARI 1855
Query: 5452 QYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLR 5631
+ +E +L+ E + + R+ E+R+ + Q +EK+ E+ EL++K K + +
Sbjct: 1856 RAIEQELDGEQRRHQDTEKNWRKAERRVKEVEFQVVEEKKNEERLTELVDKLQCKLKIFK 1915
Query: 5632 RQLDEAEDEMSRERTKHRNVQ---READDLLDANEQLTRELMN 5751
RQ++EAE+ + K++ + +A++ D E ++ N
Sbjct: 1916 RQVEEAEEVAASNLNKYKVLTAQFEQAEERADIAENALSKMRN 1958
>gi|11276953|pir||A59294 skeletal myosin - nematode (Onchocerca
volvulus)
gi|159893|gb|AAA29420.1| Major body wall myosin
Length = 1957
Score = 1082 bits (2797), Expect = 0.0
Identities = 642/1919 (33%), Positives = 1045/1919 (54%), Gaps = 20/1919 (1%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
QYL+ R +A + + +K CW+PD +G++ I D V V + +VT+
Sbjct: 13 QYLRQTREQMAAEQS-RPFDSKKNCWIPDAEDGYIAAEITSTKGDNVTV-VSARGNEVTL 70
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
+D +Q+ NPPKF+K EDMS LT+LN+ASVL+NL+ RY + LIYTYSGLFCVVINPYK+L
Sbjct: 71 KKDMLQEMNPPKFEKTEDMSNLTFLNDASVLYNLRSRYSAMLIYTYSGLFCVVINPYKRL 130
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIY+ + + GK+R EMPPH+FA++D AYR+ML + E+QS+L TGESGAGKTENTKKV
Sbjct: 131 PIYTNSVATMYMGKRRTEMPPHLFAVSDEAYRNMLVDHENQSMLITGESGAGKTENTKKV 190
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
I Y A V GA++NK + ++ LE Q++Q NP+LEAFGN+KTV+N+
Sbjct: 191 IAYFA-VVGASQNKGQDQGEKKVT------------LEDQIVQTNPVLEAFGNAKTVRNN 237
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRI+F G ++ +IE YLLEKSRV+RQA ER +HIFYQ+ + K
Sbjct: 238 NSSRFGKFIRIHFSKQGKVASCDIEHYLLEKSRVIRQAPGERCYHIFYQVFSDFNPTLKK 297
Query: 913 EYLLEG-VDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLL 1089
+ LL+ + NY F+ +T+ V+D +E T + I+ F+ +E + R+V+A++ +
Sbjct: 298 DLLLDQPLKNYYFVAQAELTIDGVNDKEEHQLTDEAFDILNFSPEEKMNCYRLVAAIMHM 357
Query: 1090 GNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQ 1269
G ++F Q + +QA K ++ G+ E KA +PR+KVG E+V+K QN +Q
Sbjct: 358 GCMKFKQRPREEQAEPDGTDEADKASNMYGIDTEEFLKALTKPRVKVGTEWVSKGQNVDQ 417
Query: 1270 AEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICI 1449
+ V A+A Y+R+FKWLVT+ NK+LD+ FIG+LDIAGFEIFD NSFEQ+ I
Sbjct: 418 VTWDVGAMANLLYDRIFKWLVTKCNKTLDQKGLTRDYFIGVLDIAGFEIFDFNSFEQLWI 477
Query: 1450 NYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEEC 1629
N+ NEKLQQ FN+ MF+LEQEEY+REGI+W FIDFGLDLQ I+LIEKPMG++++LDEEC
Sbjct: 478 NFVNEKLQQFFNHHMFVLEQEEYEREGIQWTFIDFGLDLQACIELIEKPMGIISMLDEEC 537
Query: 1630 LFPKANDKSFVEKLQKTH-NKHPKFIVP----DMRSKSHFAVVHYAGRVDYSADQWLMKN 1794
+ PKA D + +KL TH KHP F P +S++HFA+ HYAG V Y+ WL KN
Sbjct: 538 IVPKATDLTLAQKLVDTHLGKHPNFEKPKPPKGKQSEAHFAMKHYAGTVRYNVMNWLEKN 597
Query: 1795 MDPLNENVVGLM-QNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHK 1971
DPLN+ VV +M Q+ + + IWKD AA + + + G F TVS +++
Sbjct: 598 KDPLNDTVVSVMKQSKANDLLVEIWKDYTTQEESAAAKDGGGGKKKGKSGSFLTVSMMYR 657
Query: 1972 EQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNR 2151
E L LM+ L T PHF+RCIIPNH K SG ++ +VL QL CNGVLEGIRICR+GFPNR
Sbjct: 658 ESLNSLMSMLNMTHPHFIRCIIPNHNKTSGLLHRRMVLNQLTCNGVLEGIRICRKGFPNR 717
Query: 2152 VPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNL----YRIGQSKVFFRTGV 2319
+F+ RY +L K+ D K+ M++ L D L +R+G++KVFF+ GV
Sbjct: 718 NLHADFKQRYAVLAAKE-AKSEDDPKKCAEVMLSKLVNDGALTEENFRLGKTKVFFKAGV 776
Query: 2320 LAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQW 2499
LAHLE++RD KL + QA+ R + N A+ LR+W W
Sbjct: 777 LAHLEDQRDQKLGEALTGIQARIRSYRYLADRHRSMQQRHGLLVLQRNIRAWCVLRSWDW 836
Query: 2500 WRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQE 2679
+ ++ K+KP+L+ R +EI + +++ +E + E +E E +++ ER +
Sbjct: 837 FLIYGKIKPMLKCGREGEEIEKMNQQIKQLEENIANEEKARKELEANSTKLLEERNNVFN 896
Query: 2680 QLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRD 2859
+L+ +++DD RL T ++E ++++ +RL ++K V +
Sbjct: 897 ELEAAKAQLSDVDDRLNRLSTLKTDVEKQIHELEERLGDQEDRNSDLSRSKKKIENDVEN 956
Query: 2860 XXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQ 3039
DK + +Q + L
Sbjct: 957 LKKSIAELETRLQKTDADKQSREQQIRTLQDEMQQQDENIAKLNKEKKHQEEINRKLMED 1016
Query: 3040 LLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEK 3219
L E++ + K KG+LE L +LE +L RE++ ++E+E+ KRK+ EL+ +++++ E
Sbjct: 1017 LQVEEDKGNYSNKLKGKLEQSLDDLEDNLEREKRGRNEIEKQKRKIGGELKVAQENMEEI 1076
Query: 3220 MGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNAR 3399
+ E+ + L K++ E Q R +EE V ++KQ+ + Q I EL E++E ER +R
Sbjct: 1077 ERQRHEIESNLKKKETEAQAITARLEEEQDLVGKLKKQVNETQNRITELEEELENERQSR 1136
Query: 3400 NKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGK 3576
+KAE + ++ +LE++ GD LD+ AT Q ++ +++ E+ +R +E+ E +
Sbjct: 1137 SKAERAKSDLQRELEEL-GDRLDEQGGATAAQVEVNKKREAELAKLRRDLEEANMNHENQ 1195
Query: 3577 IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKK 3756
+ + K + V EL DQIEQ +K ++++EK + QA +ER D+ +I A R + +K
Sbjct: 1196 LAAIRKKHNDAVAELGDQIEQVQKAKAKIEKDKMQAQRERQDLVAQIDGETAERMNNEKL 1255
Query: 3757 RKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATA 3936
K +E + E+Q E + + R E L + EE E M R A
Sbjct: 1256 AKQYEMQIAELQTKCDEQNRQLQEFTTLKTRLNSENTDLGKQIEEAESQVNAMTRLKAQL 1315
Query: 3937 XXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHAARQG 4113
R + + + + E +L+ +EE EG+ + L K++ A
Sbjct: 1316 TSQLEEARRSLDEEARDRNNLAAQMKNYQHEIEQVLESMEEEIEGI-SELMKQLSRANAE 1374
Query: 4114 AGEARRKAEES---VNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELED 4284
+ + + E +LEE +K+ + + LQ+ L+ + + ++K ++ +L+D
Sbjct: 1375 IQQWQTRFESEGLLKGDELEESKKRQMHKMNELQETLDAANSKISSLEKTKSRLVSDLDD 1434
Query: 4285 SSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNE 4464
+ M++E + EK+QK F+ + E + + D +E R+ T + L +E
Sbjct: 1435 AQMDVERANSYASQLEKKQKGFDKVIDEWKKKTDDIATEVDNAQREARNVSTELFKLKSE 1494
Query: 4465 VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEEL 4644
D + E +E R + L QE +D + G++V E++K R LE E ++++ +++
Sbjct: 1495 QDEVLETIEGLRRENKELAQERKDLTDQLGEGGRSVFEMQKIIRRLEVEKDELQHALDQP 1554
Query: 4645 EDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRG 4824
+D L+ E LR +V +++E ++ I K+ E E R+ + I ++ LENE R
Sbjct: 1555 QDALEAEESKVLRAQVEVSQIRAEIEKRIQEKEEEFENTRKNHQRAIESMQASLENETRS 1614
Query: 4825 KSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDI 5004
K+ + +KK+E+ I ELE L+ AN+ + E Q + E ++ +
Sbjct: 1615 KADLMRLKKKLESDINELEIALDHANQANAQAQKNVKTYQDQMRELQQQVETEQRNGRNS 1674
Query: 5005 AALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXX----XRAKGGGISSEE 5172
++K +++E+E++ AN +ARKQ A+ +
Sbjct: 1675 REQYLNMEKKATLLQSEKEEMSVANGQAERARKQADYDANEAHTQCNELSAQAESLCG-S 1733
Query: 5173 KRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSL 5352
+R+L+ ++ + + + ++ + A ++ L E+ + + + +++L
Sbjct: 1734 RRKLDTELLAIQADLDETLNEYKASEERCKAASSDAARLAEQLRKEQENSLQNDRIRKAL 1793
Query: 5353 ERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKR 5532
E ++ +A++ E E A +A LE++++ LE +L+ E + N++ + E+R
Sbjct: 1794 ESQLKEMQARLDEAEVLALKGGNKDIAKLESRIRELESELDGEQRRYQETNKSLTKHERR 1853
Query: 5533 LNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+ + Q +++++ E+ ++L+EK K ++ ++Q++EAE+ + K R +Q + DD
Sbjct: 1854 IRELQFQVDEDRKNAERTRDLIEKLQNKLKSQKKQIEEAEELANVNLQKFRQIQHQLDD 1912
Score = 125 bits (313), Expect = 2e-26
Identities = 149/742 (20%), Positives = 313/742 (42%), Gaps = 17/742 (2%)
Frame = +1
Query: 3571 GKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADID 3750
G+ E+ K ++Q+++L + I +K R +LE + +ER ++ E+ +A +D+D
Sbjct: 850 GREGEEIEKMNQQIKQLEENIANEEKARKELEANSTKLLEERNNVFNELEAAKAQLSDVD 909
Query: 3751 KKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLA 3930
+ +++ + E +E L DQ +R+ D L+R +++ E+ N+++ +A
Sbjct: 910 DRLNRLSTLKTDVEKQIHELEER---LGDQEDRNSD----LSRSKKKIENDVENLKKSIA 962
Query: 3931 TAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQ 4110
TRL+ + ++ + E + L DE ++ + A L KE ++
Sbjct: 963 ELE-------------TRLQKTDADKQSR-EQQIRTLQDEMQQQDENIAKLNKE----KK 1004
Query: 4111 GAGEARRK------AEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQ 4272
E RK EE +L+ K + ++ L+ LE + + I + K+KI
Sbjct: 1005 HQEEINRKLMEDLQVEEDKGNYSNKLKGKLEQSLDDLEDNLEREKRGRNEIEKQKRKIGG 1064
Query: 4273 ELEDSSMELENVRASHRDSEK--RQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRV 4446
EL+ + +E + + E ++K+ E+Q R+ ++ L+ + + +++ + + R+
Sbjct: 1065 ELKVAQENMEEIERQRHEIESNLKKKETEAQAITARLEEEQDLVGK--LKKQVNETQNRI 1122
Query: 4447 LSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMR 4626
L E++ ++ +++R + LQ+EL++ D+ G + + EAEL +R
Sbjct: 1123 TELEEELENERQSRSKAERAKSDLQRELEELGDRLDEQGGATAAQVEVNKKREAELAKLR 1182
Query: 4627 VQMEELEDNLQIAEDARLR-------LEVTNQALKSESDRAISNKD-VEAEEKRRGLLKQ 4782
+EE N + + A +R E+ +Q + + +A KD ++A+ +R+ L+ Q
Sbjct: 1183 RDLEEANMNHE-NQLAAIRKKHNDAVAELGDQIEQVQKAKAKIEKDKMQAQRERQDLVAQ 1241
Query: 4783 IR-DLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXE 4959
I + + NEK K + E QI EL+ + + NR +E+ +
Sbjct: 1242 IDGETAERMNNEKLAK--------QYEMQIAELQTKCDEQNRQLQEFTTLKTRLNSENTD 1293
Query: 4960 YQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXX 5139
+ EEA + L + QL EA L +
Sbjct: 1294 LGKQIEEAESQVNAMTRLKAQLT----------SQLEEARRSLDE--------------- 1328
Query: 5140 RAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTL 5319
A+ + + + + +I Q + + +A +++Q T E L
Sbjct: 1329 EARDRNNLAAQMKNYQHEIEQVLESMEEEIEGISELMKQLSRANAEIQQWQTRFESEGLL 1388
Query: 5320 NQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTA 5499
+ LE S + K+ EL+ + A +++++LE L L+ +
Sbjct: 1389 ------KGDELEESKKRQMHKMNELQETLDA-ANSKISSLEKTKSRLVSDLDDAQMDVER 1441
Query: 5500 ANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTK 5679
AN A +LEK+ + ++ K+ + ++ + + RN+ +L + + E
Sbjct: 1442 ANSYASQLEKKQKGFDKVIDEWKKKTDDIATEVDNAQREARNVSTELFKLKSEQDEVLET 1501
Query: 5680 HRNVQREADDLLDANEQLTREL 5745
++RE +L + LT +L
Sbjct: 1502 IEGLRRENKELAQERKDLTDQL 1523
Score = 122 bits (305), Expect = 1e-25
Identities = 152/822 (18%), Positives = 335/822 (40%), Gaps = 18/822 (2%)
Frame = +1
Query: 3328 KQMRDMQTTIDELREDMETERNARNKAEMT-------RREVVAQLEKVKGDVLDKVDEAT 3486
+++ M I +L E++ E AR + E R V +LE K + D D
Sbjct: 854 EEIEKMNQQIKQLEENIANEEKARKELEANSTKLLEERNNVFNELEAAKAQLSDVDDRLN 913
Query: 3487 MLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLE 3666
L L + +++++ + + G E++ + SR +++ + +E KK ++LE
Sbjct: 914 RLSTLKTDVEKQIHELEERL--------GDQEDRNSDLSRSKKKIENDVENLKKSIAELE 965
Query: 3667 KQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLE 3846
+ + D ++ Q+I LQ D+ ++ ++ +E R L++ L+
Sbjct: 966 TRLQKTDADKQSREQQIRTLQDEMQQQDE-------NIAKLNKEKKHQEEINRKLMEDLQ 1018
Query: 3847 RSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXT-RLKIANINRA---R 4014
D+ ++ N+++ + E + +++ L LK+A N R
Sbjct: 1019 VEEDKGNYSNKLKGKLEQSLDDLEDNLEREKRGRNEIEKQKRKIGGELKVAQENMEEIER 1078
Query: 4015 QLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDV 4194
Q + ++ L ++ EA+ + A LE+E + G+ +++ E+ N+ +
Sbjct: 1079 QRHEIESNLKKKETEAQAITARLEEE----QDLVGKLKKQVNETQNR------------I 1122
Query: 4195 EHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEER 4374
L+++LE ++ + ++K +Q+ELE+ L+ + + KK E+++A+ R
Sbjct: 1123 TELEEELENERQSRSKAERAKSDLQRELEELGDRLDEQGGATAAQVEVNKKREAELAKLR 1182
Query: 4375 VAVQKALLDRDAMSQELRDRET-RVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNK 4551
+++A ++ + +R + V L ++++ +++ + ++ + Q+E QD ++
Sbjct: 1183 RDLEEANMNHENQLAAIRKKHNDAVAELGDQIEQVQKAKAKIEKDKMQAQRERQDLVAQI 1242
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAI 4731
D EK + E ++ +++ + +E LQ + RL N L + + A
Sbjct: 1243 DGETAERMNNEKLAKQYEMQIAELQTKCDEQNRQLQEFTTLKTRLNSENTDLGKQIEEAE 1302
Query: 4732 SNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLK 4911
S + K + L Q+ + L+ E R ++ + K +++I ++ + +E
Sbjct: 1303 SQVNAMTRLKAQ-LTSQLEEARRSLDEEARDRNNLAAQMKNYQHEIEQVLESMEEEIEGI 1361
Query: 4912 EEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLM 5091
E ++Q E K D L R+ + +E L AN +
Sbjct: 1362 SELMKQLSRANAEIQQWQTRFESEGLLKGD--ELEESKKRQMHKMNELQETLDAANSKIS 1419
Query: 5092 QARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXX-QSNCELAIDKQRKA 5268
K K +S + +++ + A Q + ID+ +K
Sbjct: 1420 SLEK-------------TKSRLVSDLDDAQMDVERANSYASQLEKKQKGFDKVIDEWKK- 1465
Query: 5269 QVQLEQITTDLSMERTLNQKTEAEKQSLE----RSNRDYKAKITELESGAQSRARAQMAA 5436
+ + I T++ N + EA S E +S +D ++ E G R +
Sbjct: 1466 --KTDDIATEVD-----NAQREARNVSTELFKLKSEQD---EVLETIEGL----RRENKE 1511
Query: 5437 LEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLK 5616
L + + L DQL G+ + RRLE ++ + + A E + + ++ ++
Sbjct: 1512 LAQERKDLTDQLGEGGRSVFEMQKIIRRLEVEKDELQHALDQPQDALEAEESKVLRAQVE 1571
Query: 5617 NRNLRRQLDEAEDEMSRE-RTKHRNVQREADDLLDANEQLTR 5739
+R ++++ E E +N QR + + + E TR
Sbjct: 1572 VSQIRAEIEKRIQEKEEEFENTRKNHQRAIESMQASLENETR 1613
Score = 77.4 bits (189), Expect = 4e-12
Identities = 128/673 (19%), Positives = 262/673 (38%), Gaps = 40/673 (5%)
Frame = +1
Query: 2512 TKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQ 2691
T++K L ++ ++ R+ D+E R +M++ E E+ L+ + E I E ++Q
Sbjct: 1309 TRLKAQL-TSQLEEARRSLDEEARDRNNLAAQMKNYQHEIEQVLESMEEEIEGISELMKQ 1367
Query: 2692 ESENSAELDDIRGRLQT----RNQELE-------YIVNDMRDRLSXXXXXXXXXXXXRRK 2838
S +AE+ + R ++ + ELE + +N++++ L + +
Sbjct: 1368 LSRANAEIQQWQTRFESEGLLKGDELEESKKRQMHKMNELQETLDAANSKISSLEKTKSR 1427
Query: 2839 QMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXX 3018
+ + D + D+ D
Sbjct: 1428 LVSDLDDAQMDVERANSYASQLEKKQKGFDKVIDEWKKKTDDIATEVDNAQREARNVSTE 1487
Query: 3019 XXGLTTQLLDHEERAKHGVKAKGR--------LENQLHELEQDLNRERQYKSELEQHKRK 3174
L ++ D G++ + + L +QL E + + ++ LE K +
Sbjct: 1488 LFKLKSEQ-DEVLETIEGLRRENKELAQERKDLTDQLGEGGRSVFEMQKIIRRLEVEKDE 1546
Query: 3175 LLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTT 3354
L L+ +D L + KV ++ + E++ ++ +EE N ++ Q
Sbjct: 1547 LQHALDQPQDALEAEESKVLRAQVEVSQIRAEIEKRIQEKEEEFENTR------KNHQRA 1600
Query: 3355 IDELREDMETERNARNKAEMTRREVVAQLEKVKGDV------LDKVDEAT-MLQDLMSRK 3513
I+ ++ +E E R+KA++ R + +K++ D+ LD ++A Q +
Sbjct: 1601 IESMQASLENE--TRSKADLMRLK-----KKLESDINELEIALDHANQANAQAQKNVKTY 1653
Query: 3514 DEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQE 3693
+++ ++ +E Q EQ ++ L + E+ Q E+ + QAD +
Sbjct: 1654 QDQMRELQQQVETEQRNGRNS-REQYLNMEKKATLLQSEKEEMSVANGQAERARKQADYD 1712
Query: 3694 RADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAES-DEHKRT-------------L 3831
+ + L A + R+ + L+ IQA+L E+ +E+K + L
Sbjct: 1713 ANEAHTQCNELSAQAESLCGSRRKLDTELLAIQADLDETLNEYKASEERCKAASSDAARL 1772
Query: 3832 IDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRA 4011
+QL + ++ +R+R+ E MQ RL A +R
Sbjct: 1773 AEQLRKEQENSLQNDRIRKALESQLKEMQARLDEAEVLALKGGNKDIAKLE------SRI 1826
Query: 4012 RQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRD 4191
R+LE E + +E E+ I + E R+ AE + +E+L+ K
Sbjct: 1827 RELESELDGEQRRYQETNKSLTKHERRIRELQFQVDEDRKNAERT-RDLIEKLQNK---- 1881
Query: 4192 VEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEE 4371
++ +KQ+EE+E LQ ++IQ +L+D+ ++ A + S+ R K A
Sbjct: 1882 LKSQKKQIEEAEELANVNLQKFRQIQHQLDDAEERADH--AENSLSKMRAKSRSGMTASP 1939
Query: 4372 RVAVQKALLDRDA 4410
V V ++ + R +
Sbjct: 1940 GVQVSQSSVLRSS 1952
>gi|12657354|emb|CAC27778.1| myosin heavy chain [Notothenia coriiceps]
Length = 1932
Score = 1079 bits (2791), Expect = 0.0
Identities = 638/1891 (33%), Positives = 1047/1891 (54%), Gaps = 17/1891 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V + +E FL G + ++ + V+ + + VT+ ++ NPPK+DKIEDM+ +T+L
Sbjct: 38 FVTEPSEMFLKGKLTKKEGGKATVDTL-CGKTVTVKDTEIFPMNPPKYDKIEDMAMMTHL 96
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E SVL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y ++ ++GKKR E PPHIF+
Sbjct: 97 SEPSVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYDSKVVNGYRGKKRIEAPPHIFS 156
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ MLQ+RE+QSIL TGESGAGKT NTK+VIQY A +A A K A+ +
Sbjct: 157 ISDNAYQFMLQDRENQSILITGESGAGKTVNTKRVIQYFATIAVAGGKKMEQASKMK--- 213
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
G LE Q++ ANP+LE++GN+KT++NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 214 ---------GSLEDQIIAANPLLESYGNAKTIRNDNSSRFGKFIRIHFGTTGKLASADIE 264
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRF-LVNRG-ITLPNV 981
YLLEKSRV Q ERS+HIFYQ++ G E E LL + Y + ++++G IT+ ++
Sbjct: 265 TYLLEKSRVTFQLSAERSYHIFYQLMTG-HKPEILEALLITKNPYDYHMISQGEITVKSI 323
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
DD++EF +T ++ I+GF DE +S+ + AV+ GN++F Q+++ +QA V K
Sbjct: 324 DDIEEFIATDAAIDILGFTLDEKASMYKQTGAVMHHGNMKFKQKQREEQAEPDGTEVADK 383
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+ +L+GL +L KA PR+KVG E+V K Q Q V A+ K+ YE++F W+V RI
Sbjct: 384 IAYLMGLNSADLLKALCYPRVKVGNEYVTKGQTVSQVNNNVSALCKSVYEKMFLWMVIRI 443
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ L T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 444 NEML-ATKQSRQFFIGVLDIAGFEIFDYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 502
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA+D +F KL H K
Sbjct: 503 KEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKASDITFKNKLYDQHLGKSAA 562
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P ++++HFA++HYAG VDY+ WL KN DPLN++VV L Q S+ +A +
Sbjct: 563 FQKPKPAKGKAEAHFALLHYAGTVDYNVTGWLEKNKDPLNDSVVQLYQKSSVKLLALL-- 620
Query: 1870 DAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHE 2049
+A AAE E + + G F+TVS L +E L KLMT LR+T PHFVRC+IPN
Sbjct: 621 ---YASHNAAEA-EGKKAAKKKGGSFQTVSALFRENLGKLMTNLRSTHPHFVRCLIPNES 676
Query: 2050 KKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDG 2226
K G + + LV+ QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L VIP+ F+D
Sbjct: 677 KTPGLMQNFLVIHQLRCNGVLEGIRICRKGFPSRIQYADFKQRYKVLNASVIPEGQFMDN 736
Query: 2227 KESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSR 2406
K++ K++ ++D+D Y+ G +KVFF+ G+L LEE RD KL L+ QA RGFLSR
Sbjct: 737 KKASEKLLGSIDVDPTQYKFGHTKVFFKAGLLGILEEMRDDKLAKLVTMTQALSRGFLSR 796
Query: 2407 RLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRA 2586
+ N +++ ++ W W +L+ K+KPLL+ ++ E+ +
Sbjct: 797 TEFQKMMERREAIYSVQYNIRSFMNVKTWPWMKLYFKIKPLLKSAESEKEMAQMKVDFAK 856
Query: 2587 TKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYI 2766
KE L K +E E+K+ ++ ++ +Q Q+Q E E + ++ L +LE
Sbjct: 857 MKEDLAKALSKKKELEEKMVSLLQDKNDLQLQMQSEGETLCDAEERCEGLIKAKIQLEAK 916
Query: 2767 VNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXX 2946
+ +RL +RK + + +K +
Sbjct: 917 CKETSERLEDEEEMNGELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 976
Query: 2947 XXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDL 3126
+ L E++ KA+ +LE Q+ +LE L
Sbjct: 977 VEEMSSQDEIIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKARVKLEQQVDDLEGSL 1036
Query: 3127 NRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEES 3306
+E++ + +LE+ KRKL +++ + + + + ++ + ++ K+D E L+R ++E
Sbjct: 1037 EQEKKLRMDLERAKRKLEGDVKLAHETIMDLENDKQQSDEKIKKKDFETSQLLSRIEDEQ 1096
Query: 3307 ANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT 3486
+QK+++++Q I+EL E++E ER AR K E R ++ +LE++ + L++ AT
Sbjct: 1097 TLSAQLQKKIKELQARIEELEEEIEAERAARAKVEKQRSDLSRELEEI-SERLEESGGAT 1155
Query: 3487 MLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQL 3663
+Q M++K E E +R +E+ E + K + V EL +QI+ ++ + +L
Sbjct: 1156 SVQIEMNKKREAEFQKLRRDLEESTLQHEATAAALRKKQADSVAELGEQIDNLQRVKQKL 1215
Query: 3664 EKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQL 3843
EK++++ E D++ + + S+ +++K + E L E++ E H + Q
Sbjct: 1216 EKEKSEYKMEIDDLSSNMESVAKSKVNLEKMCRTLEDQLSEMKTKNEEHVRHVNDIGVQR 1275
Query: 3844 ERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLE 4023
R E +R EE++ + + R + K A + +
Sbjct: 1276 ARLLTENGEYSRQMEEKDALISQLTRSKQAFTQQVEEFKRHIEEEVKAKNALAHAVQSAR 1335
Query: 4024 DEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHL 4203
+ + L ++ EE + ++ L++ + A + R K E Q+ EEL + + + L
Sbjct: 1336 HDCDLLREQYEEEQEAKSELQRAMSKANSEVAQWRAKYETDAIQRTEELEESKKKLAQRL 1395
Query: 4204 QKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEER 4374
Q E E + + ++K+++ E+ED +++E A + +K+Q+ F+ +AE +
Sbjct: 1396 QDAEESIEAVNAKCASLEKTKQRLLAEVEDLMIDVERANALAANLDKKQRNFDKVLAEWK 1455
Query: 4375 VAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKD 4554
+++ + + +E R T + L N + +HLE R ++LQQE+ D
Sbjct: 1456 QKYEESQAELEGSLKEARSLSTEMFKLKNSYEEALDHLESLKRENKNLQQEISDLTEQIG 1515
Query: 4555 DFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAIS 4734
+ GK +HELEK K+ LE E ++++ +EE E L+ E LR+++ +K E DR I+
Sbjct: 1516 ENGKTLHELEKGKKILEIEKSELQTSLEEAEATLEHEESKILRVQLELTQIKGEVDRKIA 1575
Query: 4735 NKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKE 4914
KD E ++ +R + I +++ L++E R ++ A+ +KK+E + E+E QL ANR
Sbjct: 1576 EKDEEIDQIKRNSQRVIESMQSNLDSEVRSRNDALRIKKKMEGDLNEMEIQLSHANRQAS 1635
Query: 4915 EYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQ 5094
E + + +EA + +ED+ + +R+ + AE E+LR A E +
Sbjct: 1636 EAQKQLRNVQGQLKDSLLHLDEALRGQEDMKEQVAMVERRNNLMVAEIEELRAALEQTER 1695
Query: 5095 ARKQXXXXXXXXXXXRAKGGGISSEE------KRRLEAKIAQXXXXXXXXQSNCELAIDK 5256
RK + G + S+ K++LE + Q A +K
Sbjct: 1696 CRK---VAEQELVDASERVGLLHSQNTSLINTKKKLETDLVQIQGEVEDSVQEARNAEEK 1752
Query: 5257 QRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAA 5436
+KA + +L E+ + E K++LE + +D + ++ E E+ A + Q+
Sbjct: 1753 AKKAITDAAMMAEELKKEQDTSSHLERMKKNLEVTVKDLQIRLDEAENLAMKGGKKQLQK 1812
Query: 5437 LEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLK 5616
LEA+V+ LE +++ E + A + R+ E+++ + + QFE++K+ + ++L++K LK
Sbjct: 1813 LEARVRELEGEVDAEQRRGAEAIKGVRKYERKVKELSYQFEEDKKNISRLQDLVDKLQLK 1872
Query: 5617 NRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+ +RQ +EAE++ + +K R VQ E ++
Sbjct: 1873 VKAYKRQSEEAEEQANTHLSKCRKVQHEMEE 1903
Score = 159 bits (403), Expect = 6e-37
Identities = 188/915 (20%), Positives = 387/915 (41%), Gaps = 29/915 (3%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K +++ ++++DL + K ELE+ LL + D + + E + EE
Sbjct: 845 KEMAQMKVDFAKMKEDLAKALSKKKELEEKMVSLLQDKNDLQLQMQSEGETLCDAEERCE 904
Query: 3247 QLMKRDEELQHQLTR-----YDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
L+K +L+ + DEE N L K+ R ++ EL++D++ E
Sbjct: 905 GLIKAKIQLEAKCKETSERLEDEEEMNGELTAKK-RKLEDECSELKKDID-------DLE 956
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + V+E + +++++ +E A + A +Q ++ +
Sbjct: 957 LTLAKVEKEKHATENKVKNLVEEMSSQDEIIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1016
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK 3753
+ + + K +QV++L +EQ KK R LE+ + + + + + I L+ + D+
Sbjct: 1017 TLTKARVKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDVKLAHETIMDLENDKQQSDE 1076
Query: 3754 KRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLAT 3933
K K + ++ + + E ++TL QL++ EL R+ E EE A R
Sbjct: 1077 KIKKKDFETSQLLSRI----EDEQTLSAQLQKKIKELQ--ARIEELEEEIEAERAAR--- 1127
Query: 3934 AXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQG 4113
+++ + +R+LE E + L+E A ++ + K+ A Q
Sbjct: 1128 ---------------AKVEKQRSDLSRELE-EISERLEESGGATSVQIEMNKKREAEFQ- 1170
Query: 4114 AGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELED 4284
+ RR EES Q LRKK V L +Q++ + K+++ + K + + E++D
Sbjct: 1171 --KLRRDLEESTLQHEATAAALRKKQADSVAELGEQIDNLQRVKQKLEKEKSEYKMEIDD 1228
Query: 4285 SSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNE 4464
S +E+V S + EK + E Q++E + ++ + + + D + LL E
Sbjct: 1229 LSSNMESVAKSKVNLEKMCRTLEDQLSEMKTKNEEHV-------RHVNDIGVQRARLLTE 1281
Query: 4465 VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEEL 4644
+EE D + L + Q ++F +++ E KAK +L + R + L
Sbjct: 1282 NGEYSRQMEEKDALISQLTRSKQAFTQQVEEFKRHIEEEVKAKNALAHAVQSARHDCDLL 1341
Query: 4645 EDNLQIAEDARLRL---------EVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLE 4797
+ + ++A+ L EV K E+D AI + E EE ++ L ++++D E
Sbjct: 1342 REQYEEEQEAKSELQRAMSKANSEVAQWRAKYETD-AIQRTE-ELEESKKKLAQRLQDAE 1399
Query: 4798 NELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECE 4977
+E + ++++ ++ +L +E AN L E++ + E
Sbjct: 1400 ESIEAVNAKCASLEKTKQRLLAEVEDLMIDVERANALAANLDKKQRNFDKVLAEWKQKYE 1459
Query: 4978 EARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGG 5157
E++ E R + ++ E+ + E L + K + G
Sbjct: 1460 ESQAELEGSLKEARSLSTEMFKLKNSYEEALDHLESLKRENKNLQQEISDLTEQIGENGK 1519
Query: 5158 ISSE-EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTE 5334
E EK + +I + ++ L ++ + +VQLE ++R + +K E
Sbjct: 1520 TLHELEKGKKILEIEKSELQTSLEEAEATLEHEESKILRVQLELTQIKGEVDRKIAEKDE 1579
Query: 5335 AEKQSLERSNRDYKAKITELESGAQSR--ARAQMAALEAKVQYLEDQLNVEGQEKTAANR 5508
Q S R ++ + L+S +SR A +E + +E QL+ ++ + A +
Sbjct: 1580 EIDQIKRNSQRVIESMQSNLDSEVRSRNDALRIKKKMEGDLNEMEIQLSHANRQASEAQK 1639
Query: 5509 AARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRN 5688
R ++ +L D+ ++ R E KE + +N + +++E + + +
Sbjct: 1640 QLRNVQGQLKDSLLHLDEALRGQEDMKEQVAMVERRNNLMVAEIEELRAALEQTERCRKV 1699
Query: 5689 VQREADDLLDANEQL 5733
++E L+DA+E++
Sbjct: 1700 AEQE---LVDASERV 1711
Score = 119 bits (299), Expect = 7e-25
Identities = 172/896 (19%), Positives = 356/896 (39%), Gaps = 123/896 (13%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +++ E ++ +E+D +++++K+ + E + + +++ E SA+L LQ
Sbjct: 1051 RKLEGDVKLAHETIMDLENDKQQSDEKIKKKDFETSQLLSRIEDEQTLSAQLQKKIKELQ 1110
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + R +++E + + +
Sbjct: 1111 ARIEELEEEIEAER----AARAKVEKQRSDLSRELEEISERLEESGGATSVQIEMNKKRE 1166
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K +
Sbjct: 1167 AEFQKLRRDLEESTLQHEATAAALRKKQADSVAELG---EQIDNLQRVKQKLEKEKSEYK 1223
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K LE+ R L +L + K E + V ++ Q + E
Sbjct: 1224 MEIDDLSSNMESVAKSKVNLEKMCRTLEDQLSEMKTKNEEHVRHVNDIGVQRARLLTENG 1283
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ +E+ A ++ + + + ++E + +E E A+N + + ++
Sbjct: 1284 EYSRQMEEKDALISQLTRSKQAFTQQVEEFKRHIEEEVKAKNALAHAVQSARHDCDLLRE 1343
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
++ + + LQ MS+ + EV K + IQ T E +EE K K ++++++ +
Sbjct: 1344 QYEEEQEAKSELQRAMSKANSEVAQWRAKYETDAIQRTEE--LEESKKKLAQRLQDAEES 1401
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME-------I 3789
IE + + LEK + + E D+ ++ A A++DKK++ + L E
Sbjct: 1402 IEAVNAKCASLEKTKQRLLAEVEDLMIDVERANALAANLDKKQRNFDKVLAEWKQKYEES 1461
Query: 3790 QANLAESDEHKRTLIDQ---LERSRDE-LDHLNRVREEEEHAFANMQRRLATAXXXXXXX 3957
QA L S + R+L + L+ S +E LDHL ++ E + N+Q+ ++
Sbjct: 1462 QAELEGSLKEARSLSTEMFKLKNSYEEALDHLESLKRENK----NLQQEISDLTEQIGEN 1517
Query: 3958 XXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAAR----QGAGEA 4125
+ K + LE EK+ L EEAE H E +I + Q GE
Sbjct: 1518 GKTLHELEKGK-------KILEIEKSELQTSLEEAEATLEHEESKILRVQLELTQIKGEV 1570
Query: 4126 RRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE- 4302
RK E +++++++++ + R +E +Q L+ ++ L+ KKK++ +L + ++L
Sbjct: 1571 DRKIAEK-DEEIDQIKRNSQRVIESMQSNLDSEVRSRNDALRIKKKMEGDLNEMEIQLSH 1629
Query: 4303 -------------NVRASHRDS---------------------EKRQKKFESQMAEERVA 4380
NV+ +DS E+R +++ E R A
Sbjct: 1630 ANRQASEAQKQLRNVQGQLKDSLLHLDEALRGQEDMKEQVAMVERRNNLMVAEIEELRAA 1689
Query: 4381 VQKALLDRDAMSQELRDRETRV-------LSLLN-----EVDIMKEHLEESDRVR--RSL 4518
+++ R QEL D RV SL+N E D+++ E D V+ R+
Sbjct: 1690 LEQTERCRKVAEQELVDASERVGLLHSQNTSLINTKKKLETDLVQIQGEVEDSVQEARNA 1749
Query: 4519 QQELQDSISNKDDFGKNVHE-------LEKAKRSLEAELNDMRVQMEELEDNLQIAEDAR 4677
+++ + +I++ + + + LE+ K++LE + D++++++E E+ +
Sbjct: 1750 EEKAKKAITDAAMMAEELKKEQDTSSHLERMKKNLEVTVKDLQIRLDEAENLAMKGGKKQ 1809
Query: 4678 L-RLEVTNQALKSESD-------------------------------------------- 4722
L +LE + L+ E D
Sbjct: 1810 LQKLEARVRELEGEVDAEQRRGAEAIKGVRKYERKVKELSYQFEEDKKNISRLQDLVDKL 1869
Query: 4723 ----RAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGEL 4878
+A + EAEE+ L + R +++E+E + A S K+ + E+
Sbjct: 1870 QLKVKAYKRQSEEAEEQANTHLSKCRKVQHEMEEAEERADIAESQVNKLRAKSREI 1925
Score = 92.0 bits (227), Expect = 2e-16
Identities = 166/864 (19%), Positives = 332/864 (38%), Gaps = 137/864 (15%)
Frame = +1
Query: 2542 RTDDEIRAKDDELRATKERLLKMEHDFRENEKKL-----------DQVIVERAVIQEQLQ 2688
++D++I+ KD E R+ + + +KK+ +++ ERA + +
Sbjct: 1073 QSDEKIKKKDFETSQLLSRIEDEQTLSAQLQKKIKELQARIEELEEEIEAERAARAKVEK 1132
Query: 2689 QESENSAELDDIRGRLQ------------TRNQELEYIVNDMRDRLSXXXXXXXXXXXXR 2832
Q S+ S EL++I RL+ + +E E+ RD R
Sbjct: 1133 QRSDLSRELEEISERLEESGGATSVQIEMNKKREAEF-QKLRRDLEESTLQHEATAAALR 1191
Query: 2833 RKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXX 3012
+KQ ++V + +K+ + +
Sbjct: 1192 KKQADSVAELGEQIDNLQRVKQKLEKEKS---EYKMEIDDLSSNMESVAKSKVNLEKMCR 1248
Query: 3013 XXXXGLTTQLLDHEERAKH----GVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLL 3180
L+ +EE +H GV+ + RL + E + + + S+L + K+
Sbjct: 1249 TLEDQLSEMKTKNEEHVRHVNDIGVQ-RARLLTENGEYSRQMEEKDALISQLTRSKQAFT 1307
Query: 3181 AELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTID 3360
++E+ K H+ E++ L + + + +Y+EE + +Q+ M + +
Sbjct: 1308 QQVEEFKRHIEEEVKAKNALAHAVQSARHDCDLLREQYEEEQEAKSELQRAMSKANSEVA 1367
Query: 3361 ELREDMETERNAR------NKAEMTRR--------EVV----AQLEKVKG-------DVL 3465
+ R ET+ R +K ++ +R E V A LEK K D++
Sbjct: 1368 QWRAKYETDAIQRTEELEESKKKLAQRLQDAEESIEAVNAKCASLEKTKQRLLAEVEDLM 1427
Query: 3466 DKVDEATMLQDLMSRK----DEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQI 3633
V+ A L + +K D+ + K+ E+ Q +EG ++E ++ S ++ +L +
Sbjct: 1428 IDVERANALAANLDKKQRNFDKVLAEWKQKYEESQAELEGSLKEARS-LSTEMFKLKNSY 1486
Query: 3634 EQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESD 3813
E+ L+++ QE +D+ ++I + +++K +KI E E+Q +L E++
Sbjct: 1487 EEALDHLESLKRENKNLQQEISDLTEQIGENGKTLHELEKGKKILEIEKSELQTSLEEAE 1546
Query: 3814 -----EHKRTLIDQLERS--RDELDHLNRVREEE-EHAFANMQRRLATAXXXXXXXXXXX 3969
E + L QLE + + E+D ++EE + N QR + +
Sbjct: 1547 ATLEHEESKILRVQLELTQIKGEVDRKIAEKDEEIDQIKRNSQRVIESMQSNLDSEVRSR 1606
Query: 3970 XXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESV 4149
R+K ++E + + + EA+ +++ ++ + EA R E+
Sbjct: 1607 NDALRIKKKMEGDLNEMEIQLSHANRQASEAQKQLRNVQGQLKDSLLHLDEALRGQEDMK 1666
Query: 4150 NQQLEELRKKNLR--DVEHLQKQLEESEV-----------AKERI----------LQSKK 4260
Q R+ NL ++E L+ LE++E A ER+ + +KK
Sbjct: 1667 EQVAMVERRNNLMVAEIEELRAALEQTERCRKVAEQELVDASERVGLLHSQNTSLINTKK 1726
Query: 4261 KIQQELEDSSMELENVRASHRDSEKRQKKF---ESQMAEERVAVQKALLDRDAMSQ---- 4419
K++ +L E+E+ R++E++ KK + MAEE Q + M +
Sbjct: 1727 KLETDLVQIQGEVEDSVQEARNAEEKAKKAITDAAMMAEELKKEQDTSSHLERMKKNLEV 1786
Query: 4420 ----------------------ELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQ 4533
+L+ E RV L EVD + E+ + R +++++
Sbjct: 1787 TVKDLQIRLDEAENLAMKGGKKQLQKLEARVRELEGEVDAEQRRGAEAIKGVRKYERKVK 1846
Query: 4534 DSISNKDDFGKNVHEL------------------EKAKRSLEAELNDMRV---QMEELED 4650
+ ++ KN+ L E+A+ L+ R +MEE E+
Sbjct: 1847 ELSYQFEEDKKNISRLQDLVDKLQLKVKAYKRQSEEAEEQANTHLSKCRKVQHEMEEAEE 1906
Query: 4651 NLQIAEDARLRLEVTNQALKSESD 4722
IAE +L ++ + D
Sbjct: 1907 RADIAESQVNKLRAKSREIVKSKD 1930
Score = 67.8 bits (164), Expect = 3e-09
Identities = 104/500 (20%), Positives = 213/500 (41%), Gaps = 26/500 (5%)
Frame = +1
Query: 4324 DSEKRQKKFESQMAEERVAVQKALLDRDAMSQE----LRDRETRVLSLLNEVDIM---KE 4482
+SEK + + A+ + + KAL + + ++ L+D+ L + +E + + +E
Sbjct: 842 ESEKEMAQMKVDFAKMKEDLAKALSKKKELEEKMVSLLQDKNDLQLQMQSEGETLCDAEE 901
Query: 4483 HLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQI 4662
E + + L+ + +++ +D + EL KR LE E ++++ +++LE L
Sbjct: 902 RCEGLIKAKIQLEAKCKETSERLEDEEEMNGELTAKKRKLEDECSELKKDIDDLELTLAK 961
Query: 4663 AEDARLRLEVTNQALKSESDRAISNKDVEAE--EKRRGLLKQIRDLENELENEKRGKSGA 4836
E + T +K+ + S ++ A+ ++++ L + + ++L+ E+ +
Sbjct: 962 VEKEK---HATENKVKNLVEEMSSQDEIIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1018
Query: 4837 VSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALL 5016
R K+E Q+ +LE LE +L+ + + + + + A + D+
Sbjct: 1019 TKARVKLEQQVDDLEGSLEQEKKLRMDLERAKR-------KLEGDVKLAHETIMDLENDK 1071
Query: 5017 READRKFRAVEAEREQL--REANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEA 5190
+++D K + + E QL R +E + A+ Q ++ + L+A
Sbjct: 1072 QQSDEKIKKKDFETSQLLSRIEDEQTLSAQLQ--------------------KKIKELQA 1111
Query: 5191 KIAQXXXXXXXXQSNCELAIDKQRK-AQVQLEQITTDL-------SMERTLNQKTEAEKQ 5346
+I + ++ ++KQR +LE+I+ L S++ +N+K EAE Q
Sbjct: 1112 RIEELEEEIEAERA-ARAKVEKQRSDLSRELEEISERLEESGGATSVQIEMNKKREAEFQ 1170
Query: 5347 SLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLE 5526
L R ES Q A A AAL K D + G++ R ++LE
Sbjct: 1171 KLRRDLE---------ESTLQHEATA--AALRKK---QADSVAELGEQIDNLQRVKQKLE 1216
Query: 5527 KRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREAD 5706
K ++ + +D E + KS + NL + ED++S +TK+ R +
Sbjct: 1217 KEKSEYKMEIDD----LSSNMESVAKSKV---NLEKMCRTLEDQLSEMKTKNEEHVRHVN 1269
Query: 5707 D-------LLDANEQLTREL 5745
D LL N + +R++
Sbjct: 1270 DIGVQRARLLTENGEYSRQM 1289
>gi|30268331|emb|CAD89954.1| hypothetical protein [Homo sapiens]
Length = 1331
Score = 1078 bits (2789), Expect = 0.0
Identities = 609/1374 (44%), Positives = 844/1374 (61%), Gaps = 44/1374 (3%)
Frame = +1
Query: 403 FKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGA 582
+KGKKRHEMPPHI+AI DTAYRSM+Q+REDQSILCTGESGAGKTENTKKVIQYLA+VA +
Sbjct: 2 YKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASS 61
Query: 583 TRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIR 762
++K GELE QLLQANPILEAFGN+KTVKNDNSSRFGKFIR
Sbjct: 62 HKSKKDQ-----------------GELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIR 104
Query: 763 INFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNY 942
INFD++GYI GANIE YLLEKSR +RQA++ER+FHIFY +L G K++ LLE + Y
Sbjct: 105 INFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKY 164
Query: 943 RFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKS 1122
RFL N +T+P D F T+ +MRIMG ++E ++RV+S VL LGN+ F +E+ +
Sbjct: 165 RFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNT 224
Query: 1123 DQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKA 1302
DQA + D+ QKV HLLG+ V + + L PRIKVGR++V KAQ +EQA+FA+EA+AKA
Sbjct: 225 DQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKA 284
Query: 1303 SYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLF 1482
+YER+F+WLV RINK+LD+T RQGASFIGILDIAGFEIFD+NSFEQ+CINYTNEKLQQLF
Sbjct: 285 TYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLF 344
Query: 1483 NNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDEECLFPKANDK 1653
N+TMFILEQEEYQREGIEW+FIDFGLDLQP IDLIEKP G+LALLDEEC FPKA DK
Sbjct: 345 NHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDK 404
Query: 1654 SFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLM 1830
SFVEK+ + HPKF P ++ K+ F ++HYAG+VDY AD+WLMKNMDPLN+N+ L+
Sbjct: 405 SFVEKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLL 464
Query: 1831 QNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQLHKEQLTKLMTT 1998
S+D FV+ +WKD + G+ A M+ETA ++RKGMFRTV QL+KEQL KLM T
Sbjct: 465 HQSSDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMAT 524
Query: 1999 LRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHR 2178
LRNT+P+FVRCIIPNHEKK+GK++ +LVL+QLRCNGVLEGIRICRQGFPNRV FQEFR R
Sbjct: 525 LRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQR 584
Query: 2179 YEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLT 2358
YEILTP+ IPK F+DGK++ MI AL++D+NLYRIGQSKVFFR GVLAHLEEERDLK+T
Sbjct: 585 YEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKIT 644
Query: 2359 ALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQV 2538
+I+ FQA CRG+L+R+ + N AYLKLRNWQWWRLFTKVKPLLQV
Sbjct: 645 DVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQV 704
Query: 2539 TRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELD 2718
+R ++E+ AK++EL +E+ L E+ E E Q++ E+ +QEQLQ E+E AE +
Sbjct: 705 SRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAE 764
Query: 2719 DIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXX 2898
++R RL + QELE I +D+ R+ ++K + +++
Sbjct: 765 ELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQ 824
Query: 2899 XXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVK 3078
+K + ++ D LDH+ ++ ++
Sbjct: 825 KLQLEKVTTE-------AKLKKLEEELDDLLVD---------------LDHQRQSACNLE 862
Query: 3079 AKGRLENQLHELEQDLNRE---RQYKSELEQHKRKLLA-ELEDSKDHLAEKMGKVEELNN 3246
K + +QL E+ ++ + + ++E E +++ A L + + E+ ++E LN
Sbjct: 863 KKQKKFDQLLAEEKTISAKYAGERDRAEAEAREKETKALSLARALEEAMEQKAELERLNK 922
Query: 3247 QLMKRDEELQHQLTRYDEESANVTLMQK-------QMRDMQTTIDELREDMETERNARNK 3405
Q E+L ++ D+ +V ++K Q+ +M+T ++EL +++ +A+ +
Sbjct: 923 QFRTEMEDL---MSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEGELQATEDAKLR 979
Query: 3406 AEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEE 3585
E+ + + AQ E+ DL R ++ K+ + Q++ ME ++E+
Sbjct: 980 LEVNLQAMKAQFER----------------DLQGRDEQSEEKKKQLVRQVRE-MEAELED 1022
Query: 3586 Q----------KAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQAS 3735
+ + K +++L I+ K R + KQ + + D +E+ +AS
Sbjct: 1023 ERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRAS 1082
Query: 3736 RADI-------DKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEE 3894
R +I +KK K EA ++++Q LA ++ KR Q ++ RDEL +
Sbjct: 1083 REEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKR----QAQQERDELADEIANSSGK 1138
Query: 3895 EHAFANMQRRLATAXXXXXXXXXXXXXXT-----RLKIANINRARQLEDEKNALLDEKEE 4059
+RRL T RLK AN+ + Q+ + N ++
Sbjct: 1139 GALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANL-QIDQINTDLNLERSHAQK 1197
Query: 4060 AEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKE 4239
E R LE++ + E + + L K + E L + +E + A +
Sbjct: 1198 NENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACK 1257
Query: 4240 RILQSKKKIQQ---ELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKA 4392
++ +++KK++ +++D E + + R K+ + Q+ E Q+A
Sbjct: 1258 QVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRA 1311
Score = 377 bits (967), Expect = e-102
Identities = 212/563 (37%), Positives = 349/563 (61%), Gaps = 12/563 (2%)
Frame = +1
Query: 4015 QLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAG--EARRKAEESVNQQLEELRKKNLR 4188
QL+++ A + EAE LRA L + + EAR + EE Q L+ +KK +
Sbjct: 748 QLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQ 807
Query: 4189 DVEHLQKQLEESEVAKERILQSK-------KKIQQELEDSSMELENVRASHRDSEKRQKK 4347
+++ L++QLEE E A++++ K KK+++EL+D ++L++ R S + EK+QKK
Sbjct: 808 NIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEELDDLLVDLDHQRQSACNLEKKQKK 867
Query: 4348 FESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQE 4527
F+ +AEE+ K +RD E R++ET+ LSL ++ E E +R+ + + E
Sbjct: 868 FDQLLAEEKTISAKYAGERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTE 927
Query: 4528 LQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQAL 4707
++D +S+KDD GK+VHELEK+KR+LE ++ +M+ Q+EELE LQ EDA+LRLEV QA+
Sbjct: 928 MEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEGELQATEDAKLRLEVNLQAM 987
Query: 4708 KSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQ 4887
K++ +R + +D ++EEK++ L++Q+R++E ELE+E++ +S AV+ RKK+E + +LE
Sbjct: 988 KAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAH 1047
Query: 4888 LEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQL 5067
++ AN+ ++E + E ++ R ++E+I A +E ++K +++EAE QL
Sbjct: 1048 IDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQL 1107
Query: 5068 REANEGLMQARKQXXXXXXXXXXXRAKG---GGISSEEKRRLEAKIAQXXXXXXXXQSNC 5238
+E +A++Q A G ++ EEKRRLEA+IAQ Q N
Sbjct: 1108 QEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNT 1167
Query: 5239 ELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRA 5418
EL D+ +KA +Q++QI TDL++ER+ QK E +Q LER N++ K K+ E+E +S+
Sbjct: 1168 ELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKY 1227
Query: 5419 RAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELL 5598
+A + ALEAK+ LE+QL+ E +E+ AA + RR EK+L D Q +DE+R EQ K+
Sbjct: 1228 KASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQA 1287
Query: 5599 EKSNLKNRNLRRQLDEAEDEMSR 5667
+K++ + + L+RQL+EAE+E R
Sbjct: 1288 DKASTRLKQLKRQLEEAEEEAQR 1310
Score = 147 bits (370), Expect = 4e-33
Identities = 157/686 (22%), Positives = 300/686 (42%), Gaps = 15/686 (2%)
Frame = +1
Query: 3094 ENQLHELE---QDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRD 3264
EN+L E+E L E+ E Q + +L AE E+ + L K ++EE+ + L
Sbjct: 729 ENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLE--- 785
Query: 3265 EELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLE 3444
R +EE +Q + + MQ I EL E +E E +AR K ++ + A+L+
Sbjct: 786 -------ARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLK 838
Query: 3445 KVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELH 3624
K++ ++ D +L DL ++ N +E+++ KF + + E
Sbjct: 839 KLEEELDD------LLVDLDHQRQSACN----------------LEKKQKKFDQLLAEEK 876
Query: 3625 DQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLA 3804
++ +R + E + + + + +A R + EA ME +A L
Sbjct: 877 TISAKYAGERDRAEAEAREKETKALSLA----------------RALEEA--MEQKAELE 918
Query: 3805 ESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTR 3984
++ RT ++ L S+D++ E+ + A + T
Sbjct: 919 RLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKT----------------- 961
Query: 3985 LKIANINRARQLEDEKNALLDEKEEAE----GLRAHLEKEIHAARQGAGEARRKAEESVN 4152
+ +LE E A D K E ++A E+++ QG E
Sbjct: 962 -------QLEELEGELQATEDAKLRLEVNLQAMKAQFERDL----QGRDE---------- 1000
Query: 4153 QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSE 4332
Q EE +K+ +R V ++ +LE+ + + ++KK++ +L+D +++ + ++
Sbjct: 1001 -QSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAI 1059
Query: 4333 KRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRR 4512
K+ +K ++QM + + R+ + + ++ E ++ S+ E+ ++E L ++R +R
Sbjct: 1060 KQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKR 1119
Query: 4513 SLQQ---ELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAED---- 4671
QQ EL D I+N GK LE+ KR LEA + + ++EE + N ++ D
Sbjct: 1120 QAQQERDELADEIANSS--GKGALALEE-KRRLEARIAQLEEELEEEQGNTELINDRLKK 1176
Query: 4672 ARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENEL-ENEKRGKSGAVSHR 4848
A L+++ N L E A N E R+ L +Q ++L+ +L E E KS +
Sbjct: 1177 ANLQIDQINTDLNLERSHAQKN-----ENARQQLERQNKELKVKLQEMEGTVKSKYKASI 1231
Query: 4849 KKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREAD 5028
+E +I +LE+QL+ N KE Q C++ R+ ++ + +L + D
Sbjct: 1232 TALEAKIAQLEEQLD--NETKER---------------QAACKQVRRTEKKLKDVLLQVD 1274
Query: 5029 RKFRAVEAEREQLREANEGLMQARKQ 5106
+ R E ++Q +A+ L Q ++Q
Sbjct: 1275 DERRNAEQYKDQADKASTRLKQLKRQ 1300
Score = 115 bits (287), Expect = 2e-23
Identities = 144/656 (21%), Positives = 280/656 (41%), Gaps = 20/656 (3%)
Frame = +1
Query: 3502 MSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSR--QVEELHDQIEQHKKQRSQLEKQQ 3675
+SR++EE+ A + + +++ E+Q A +R ++E L Q+ K Q ++Q
Sbjct: 704 VSRQEEEMMAKEEELVKVR-------EKQLAAENRLTEMETLQSQLMAEKLQL----QEQ 752
Query: 3676 NQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSR 3855
QA+ E A+E+ RA + K++ E +++A + E +E + L + ++ +
Sbjct: 753 LQAETELCAEAEEL------RARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQ 806
Query: 3856 DELDHLNRVREEEEHAFANMQRRLATAXX------XXXXXXXXXXXXTRLKIANINRARQ 4017
+ L EEEE A +Q T R N+ + ++
Sbjct: 807 QNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEELDDLLVDLDHQRQSACNLEKKQK 866
Query: 4018 LEDEKNALLDEK---EEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQ--QLEELRKKN 4182
D+ L +EK + G R E E A R EE++ Q +LE L K+
Sbjct: 867 KFDQ--LLAEEKTISAKYAGERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQF 924
Query: 4183 LRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQM 4362
++E L ++ + + +SK+ ++Q++E+ +LE + + +E + + E +
Sbjct: 925 RTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEGELQATEDAKLRLEVNL 984
Query: 4363 AEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRV--RRSLQQELQD 4536
+ ++ L RD S+E + + R + + E ++ E + S V R+ L+ +L+D
Sbjct: 985 QAMKAQFERDLQGRDEQSEEKKKQLVRQVREM-EAELEDERKQRSMAVAARKKLEMDLKD 1043
Query: 4537 SISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKS- 4713
++ D KN E K R L+A++ D M EL+D E+ + + + LKS
Sbjct: 1044 LEAHIDSANKNRDEAIKQLRKLQAQMKDC---MRELDDTRASREEILAQAKENEKKLKSM 1100
Query: 4714 ESDRAISNKDVEAEEKRRGLLKQIRD-LENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
E++ +++ A E+ + +Q RD L +E+ N + A+ ++++E +I +LE++L
Sbjct: 1101 EAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEEL 1160
Query: 4891 EVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLR 5070
E +E+ QI+ Q D+ A + E R+QL
Sbjct: 1161 E-----EEQGNTELINDRLKKANLQID-----QINTDLNLERSHAQKN----ENARQQLE 1206
Query: 5071 EANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEK---RRLEAKIAQXXXXXXXXQSNCE 5241
N+ L ++ G + S+ K LEAKIAQ +
Sbjct: 1207 RQNKELKVKLQEME-------------GTVKSKYKASITALEAKIAQLEEQLDNETKERQ 1253
Query: 5242 LAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQ 5409
A + R+ + +L+ + + ER ++ + + + K ++ E E AQ
Sbjct: 1254 AACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQ 1309
Score = 113 bits (283), Expect = 5e-23
Identities = 127/591 (21%), Positives = 241/591 (40%), Gaps = 47/591 (7%)
Frame = +1
Query: 3034 TQLLDHEERAKHGVKAKGR-LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL 3210
T+L E + + AK + LE H+LE + E + L+ K+K+ +++ ++ L
Sbjct: 757 TELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQL 816
Query: 3211 AEKMGKVEEL-------NNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELR 3369
E+ ++L +L K +EEL L D + + ++K+ + + E +
Sbjct: 817 EEEESARQKLQLEKVTTEAKLKKLEEELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEK 876
Query: 3370 EDMETERNARNKAEMTRRE---VVAQLEKVKGDVLDKVDE--------ATMLQDLMSRKD 3516
R++AE RE L + + +++ E T ++DLMS KD
Sbjct: 877 TISAKYAGERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKD 936
Query: 3517 E------EVNATKRAIEQIQHTMEGKIEE---------------------QKAKFSRQVE 3615
+ E+ +KRA+EQ M+ ++EE KA+F R ++
Sbjct: 937 DVGKSVHELEKSKRALEQQVEEMKTQLEELEGELQATEDAKLRLEVNLQAMKAQFERDLQ 996
Query: 3616 ELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQA 3795
+Q E+ KK QL +Q + + E D ++ ++ A+R ++ K EAH+
Sbjct: 997 GRDEQSEEKKK---QLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANK 1053
Query: 3796 NLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXX 3975
N E+ + R L Q++ ELD REE +++L +
Sbjct: 1054 NRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAA 1113
Query: 3976 XTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQ 4155
R K RQ + E++ L DE + G A
Sbjct: 1114 AERAK-------RQAQQERDELADEIANSSGKGA-------------------------L 1141
Query: 4156 QLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEK 4335
LEE R+ R + L+++LEE + E I KK +++ + +L R+ + +E
Sbjct: 1142 ALEEKRRLEAR-IAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNEN 1200
Query: 4336 RQKKFESQMAEERVAVQKAL-LDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRR 4512
+++ E Q E +V +Q+ + + E ++ L ++D + + + + R
Sbjct: 1201 ARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVR 1260
Query: 4513 SLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIA 4665
+++L+D + DD +N + + L ++ Q+EE E+ Q A
Sbjct: 1261 RTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRA 1311
Score = 103 bits (256), Expect = 7e-20
Identities = 108/526 (20%), Positives = 221/526 (41%), Gaps = 46/526 (8%)
Frame = +1
Query: 4306 VRASHRDSEKRQKKFES-QMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKE 4482
++ S ++ E K+ E ++ E+++A + L + + + +L + L L ++ E
Sbjct: 702 LQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEK---LQLQEQLQAETE 758
Query: 4483 HLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQI 4662
E++ +R L + Q+ D V E E+ + L+AE M+ ++ELE+ L+
Sbjct: 759 LCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEE 818
Query: 4663 AEDARLRLE---VTNQALKSESDRAISNKDVEAEEKRRG---LLKQIRDLENELENEKRG 4824
E AR +L+ VT +A + + + + V+ + +R+ L K+ + + L EK
Sbjct: 819 EESARQKLQLEKVTTEAKLKKLEEELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTI 878
Query: 4825 KSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDI 5004
+ R + E + E E + R EE +++ E E+ +K+D+
Sbjct: 879 SAKYAGERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDV 938
Query: 5005 AALLREADRKFRAVEAEREQLR---EANEGLMQARKQXXXXXXXXXXXRA-------KGG 5154
+ E ++ RA+E + E+++ E EG +QA + +G
Sbjct: 939 GKSVHELEKSKRALEQQVEEMKTQLEELEGELQATEDAKLRLEVNLQAMKAQFERDLQGR 998
Query: 5155 GISSEEKRR-----------------------------LEAKIAQXXXXXXXXQSNCELA 5247
SEEK++ LE + N + A
Sbjct: 999 DEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEA 1058
Query: 5248 IDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQ 5427
I + RK Q Q++ +L R ++ A+ + E+ + +A++ +L+ + RA+
Sbjct: 1059 IKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAK 1118
Query: 5428 MAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKS 5607
A + + + ++ N G+ A RRLE R+ ++ E+E+ E + L+K+
Sbjct: 1119 RQAQQERDELADEIANSSGKGALALEEK-RRLEARIAQLEEELEEEQGNTELINDRLKKA 1177
Query: 5608 NLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
NL Q+D+ +++ ER+ + + L N++L +L
Sbjct: 1178 NL-------QIDQINTDLNLERSHAQKNENARQQLERQNKELKVKL 1216
>gi|47211780|emb|CAF94090.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 1910
Score = 1078 bits (2787), Expect = 0.0
Identities = 666/1913 (34%), Positives = 1029/1913 (52%), Gaps = 29/1913 (1%)
Frame = +1
Query: 58 LAAWAQR----KLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPP 225
LAA AQ K W+PD E ++ +K + VE D R + + +D+Q NPP
Sbjct: 25 LAAKAQAFDGTKRVWMPDDAEAYVEVEVKELNGSKSTVETKD-GRFLIVKEEDLQPMNPP 83
Query: 226 KFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEF 405
KFD IEDM+ LT+LNEASVL NLK RY +IYTYSGLFCV +NPYK LP+YS D++ +
Sbjct: 84 KFDMIEDMAMLTHLNEASVLFNLKRRYSMWMIYTYSGLFCVTVNPYKWLPVYSTDVVSAY 143
Query: 406 KGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVA--G 579
KG++R + PPHI+AIAD+AY +LQ RE+QS+L TGESGAGKT NTK+VIQY A VA G
Sbjct: 144 KGRRRVDTPPHIYAIADSAYTDLLQNRENQSMLITGESGAGKTVNTKRVIQYFAIVAALG 203
Query: 580 ATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFI 759
T + G LE Q+++ANP +EAFGN+KT++NDNSSRFGKFI
Sbjct: 204 ETIKTGVGFLIS-------------GSLEDQIIEANPAMEAFGNAKTIRNDNSSRFGKFI 250
Query: 760 RINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD- 936
RI+F +G ++ A+I+ YLLEKSRV+ Q ERS+HI+YQIL E + LL +
Sbjct: 251 RIHFGTTGKLASADIDIYLLEKSRVVFQQPAERSYHIYYQIL-SSHKPELQDMLLVTTNP 309
Query: 937 -NYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQE 1113
+Y F + +++D +E T ++M +GF +E ++V A++ GN++F ++
Sbjct: 310 YDYHFCSQGETKVDSINDGEELKLTDHAMDTLGFTPEEKYGCYKIVGAIMHFGNMKFKKK 369
Query: 1114 KKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAI 1293
++ +QA + K +L+G+ EL K L PR+KVG E++ K Q EQ +AV A+
Sbjct: 370 QREEQAEADGTESVDKAAYLMGISSAELLKGLLNPRVKVGNEYIVKGQTVEQVNYAVAAL 429
Query: 1294 AKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQ 1473
AKA+Y+R+FKWLV RIN SL T FIG+LDIAGFEIF+ NSFEQ+CIN+TNEKLQ
Sbjct: 430 AKATYDRMFKWLVGRINSSLS-TALPRQYFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQ 488
Query: 1474 QLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDK 1653
Q FN+ MFILEQEEY+ EGIEW FIDFGLDLQ IDLIE+P+G+L++L+EEC+FPKA D
Sbjct: 489 QYFNHHMFILEQEEYKVEGIEWTFIDFGLDLQACIDLIERPLGILSILEEECMFPKATDH 548
Query: 1654 SFVEKLQKTH-NKHPKFIVPDMRSK----SHFAVVHYAGRVDYSADQWLMKNMDPLNENV 1818
SF KL H K P F P + K +HF VVHYAG V Y+ WL KN DPLNE V
Sbjct: 549 SFKTKLYDNHLGKSPNFQRPRLDKKRKYETHFEVVHYAGVVPYNIIGWLDKNRDPLNETV 608
Query: 1819 VGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRK-GMFRTVSQLHKEQLTKLMT 1995
V + Q S + +AG++++ + + ++T R RK F+TVSQLHKE L KLM
Sbjct: 609 VAVFQKSANKLMAGLFENYIRSDMIDDSKSQTK--QRKRKAASFQTVSQLHKENLNKLMA 666
Query: 1996 TLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRH 2175
LR+T PHFVRCIIPN K G ++ LVL QLRCNGVLEGIRICR+GFPNR+ + EF+
Sbjct: 667 NLRSTQPHFVRCIIPNESKNPGVMDPFLVLHQLRCNGVLEGIRICRKGFPNRILYAEFKQ 726
Query: 2176 RYEILTPDVIPK-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLK 2352
RY IL IP+ +F+D +++V K++ +LDID N Y+ GQ+KVFF+ G+L LE+ RD +
Sbjct: 727 RYRILNASAIPEASFVDSRKAVEKLLGSLDIDHNQYKFGQTKVFFKAGLLGQLEDMRDAR 786
Query: 2353 LTALIMNFQAQCRGFLSR--RLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKP 2526
L+ ++ QA RG L R R N A+ +R W W LF K++P
Sbjct: 787 LSEILTIVQAMSRGTLMRMERDKMMLQRQVDAVKVIQFNLRAFFSVRTWPWMMLFYKLRP 846
Query: 2527 LLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENS 2706
+L+ + + E+ +++ K+ + E RE E + +I E+ + QLQ
Sbjct: 847 MLRSAQVEKELATLNEDFTKLKDAFDRCEVKRREAEDRQVVLIQEKNDLTLQLQAGQGTL 906
Query: 2707 AELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXX 2886
+ +D +L E + + ++RL + + E V
Sbjct: 907 EDAEDRCNQLIQSKIAQEAKLKEFQERLEDEEEVNSKLTSKKCQLEEEVTSLKRDVDDLE 966
Query: 2887 XXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAK 3066
D+ V+ + + L E++
Sbjct: 967 MTLAKVEKDRHGVENKVKNLSQEMSVLDETIASLNREKVALQEAHQQVLNDLRSQEDKVN 1026
Query: 3067 HGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNN 3246
VKAK RLE Q+ L E++ + ELE+ KRKL +L+ S D + + EE+ +
Sbjct: 1027 MLVKAKLRLEQQIDNTVSSLELEKKARMELERTKRKLEGDLKLSVDSQKDLESQKEEVED 1086
Query: 3247 QLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRRE 3426
+L K+D EL H + +EE + V +QK+++++QT I+EL E +E ER R KAE R +
Sbjct: 1087 RLKKKDIELAHLQAKLEEEQSLVAQLQKKLKELQTRIEELEEALEAERAYRTKAERQRND 1146
Query: 3427 VVAQLEKVKGDVLDKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFS 3603
+ +LE++ G+ L++ A+ Q ++RK E + +R +E E + K S
Sbjct: 1147 MARELEEL-GEKLEEAGGASAAQIALNRKREADFLKLRRELEDAALHHETTTTALRKKHS 1205
Query: 3604 RQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLM 3783
V EL +Q++ ++ + +LEK++ + E D++ + L ++A ++K + E L
Sbjct: 1206 ETVTELSEQMDTLQRAKQKLEKEKAELQLEADDLSASVEQLSRAKAAVEKVCRTFEDQLN 1265
Query: 3784 EIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXX 3963
E + E + Q R+ E L+R EE + +QR A
Sbjct: 1266 ESKNRANELQRQLNEVSAQKARALSETAELSRRLEERDSLIGQLQRSKAAVIQNHEDLKK 1325
Query: 3964 XXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEE 4143
++ + + + + + L ++ EE RA L++ + A + R K E
Sbjct: 1326 QQEEESKTRAGLAHALQSSRLDCSLLREQLEEEREARAELQRALSNANTHVVQWRTKYET 1385
Query: 4144 SVNQQLEEL---RKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRA 4314
++EEL +KK + ++ L++ + ++ + ++K+ +Q E+ED +ELE +
Sbjct: 1386 EAVLRIEELEDAKKKLVVKLQRLEEAVGAAQAKCSSLEKTKQSLQIEIEDLVIELERSNS 1445
Query: 4315 SHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEE 4494
+++ EK+Q+ + +++ ++ +++ ++ +A E R T + L N + EHLE
Sbjct: 1446 ANQALEKKQRNIDKLLSDWKLRFEESQMELEASQTESRSLSTELFKLKNCYEEALEHLET 1505
Query: 4495 SDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDA 4674
R R+LQ+E+ D GK +HELE+ ++ L+ E +D+R +EE E L+ E
Sbjct: 1506 VKRENRNLQEEIADLTDQISQGGKTIHELERMRKILDVEKSDIRAALEEAEGTLEHEESK 1565
Query: 4675 RLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKK 4854
LR + Q ++E +R I+ K+ E + RR + + ++ LE E RG+S AV RKK
Sbjct: 1566 ILRFQTELQQTRAEMERRIAEKEEEIDNLRRNHQRSLETMQASLEAEVRGRSEAVRLRKK 1625
Query: 4855 IENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEE----ARQAKEDIAALLRE 5022
+E + ++E QL ANR E E+Q+E +E Q +E I L
Sbjct: 1626 MEADMNDMEIQLAHANRQATESQRMNRNLQTQVKEHQLELDEKFHLLGQLREQIVLL--- 1682
Query: 5023 ADRKFRAVEAEREQLREANEGLMQARK----QXXXXXXXXXXXRAKGGGISSEEKRRLEA 5190
+R+ + AE E+LR E ++RK + A+ G++S +K+RLEA
Sbjct: 1683 -ERRCSLLTAEEEELRGILEQSDRSRKAAEHELVEAAETVHLLTAQNTGLAS-QKKRLEA 1740
Query: 5191 KIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRD 5370
++ + + ++R A+ ++ TD+
Sbjct: 1741 DLS-------VLSGEVDDVLQERRSAEEHAKKALTDV----------------------- 1770
Query: 5371 YKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQ 5550
K+ E+E A + ++ LE +V+ L+ +L VE + + RR E+R + +
Sbjct: 1771 ---KLDEVEQMALKGGKKELHKLEGRVRELQTELMVEQKRSEEYQKGVRRYERRCRELSS 1827
Query: 5551 QFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
Q +++ + + +E++ K K ++ +RQ + AE+++S + R VQ E D+
Sbjct: 1828 QTDEDNKTLLRMQEMISKLQTKVKSYKRQAESAEEQVSCSTVRFRKVQHELDE 1880
Score = 67.0 bits (162), Expect = 5e-09
Identities = 100/573 (17%), Positives = 227/573 (39%), Gaps = 5/573 (0%)
Frame = +1
Query: 4036 ALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQL 4215
+ +D ++ E L L+ + + + G + KA + QLE++R L ++ + + +
Sbjct: 740 SFVDSRKAVEKLLGSLDIDHNQYKFGQTKVFFKA--GLLGQLEDMRDARLSEILTIVQAM 797
Query: 4216 EESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKAL 4395
+ R+ + K +Q++++ + N+RA R + + R ++ A
Sbjct: 798 SRGTLM--RMERDKMMLQRQVDAVKVIQFNLRAFF---SVRTWPWMMLFYKLRPMLRSAQ 852
Query: 4396 LDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRV----RRSLQQELQDSISNKDDFG 4563
++++ + L + T++ + ++ + E+ V + L +LQ +D
Sbjct: 853 VEKELAT--LNEDFTKLKDAFDRCEVKRREAEDRQVVLIQEKNDLTLQLQAGQGTLEDAE 910
Query: 4564 KNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
++L ++K + EA+L + + ++E+ E E + +++K
Sbjct: 911 DRCNQLIQSKIAQEAKLKEFQERLEDEE----------------------EVNSKLTSKK 948
Query: 4744 VEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYX 4923
+ EE+ L + + DLE L ++ + G +EN++ L Q++ V L E
Sbjct: 949 CQLEEEVTSLKRDVDDLEMTLAKVEKDRHG-------VENKVKNLSQEMSV---LDETIA 998
Query: 4924 XXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARK 5103
+Q + R ++ + L++ R + ++ L + M+ +
Sbjct: 999 SLNREKVALQEAHQQVLNDLRSQEDKVNMLVKAKLRLEQQIDNTVSSLELEKKARMELER 1058
Query: 5104 QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLE 5283
KR+LE + +S E D+ +K ++L
Sbjct: 1059 T----------------------KRKLEGDLKLSVDSQKDLESQKEEVEDRLKKKDIELA 1096
Query: 5284 QITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLE 5463
+ L E++L + + + + L+ + + + E E +++A Q + +++ L
Sbjct: 1097 HLQAKLEEEQSLVAQLQKKLKELQTRIEELEEAL-EAERAYRTKAERQRNDMARELEELG 1155
Query: 5464 DQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKN-RNLRRQL 5640
++L G A R+ E ++ ED +E L K + + L Q+
Sbjct: 1156 EKLEEAGGASAAQIALNRKREADFLKLRRELEDAALHHETTTTALRKKHSETVTELSEQM 1215
Query: 5641 DEAEDEMSRERTKHRNVQREADDLLDANEQLTR 5739
D + + + +Q EADDL + EQL+R
Sbjct: 1216 DTLQRAKQKLEKEKAELQLEADDLSASVEQLSR 1248
>gi|34870892|ref|XP_340820.1| similar to Myosin heavy chain, skeletal
muscle, perinatal (MyHC-perinatal) [Rattus norvegicus]
Length = 1951
Score = 1068 bits (2763), Expect = 0.0
Identities = 633/1900 (33%), Positives = 1041/1900 (54%), Gaps = 26/1900 (1%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V + E ++ I+ + +V V+ ++ +T+ D V NPPK+DKIEDM+ +T+L
Sbjct: 41 FVAEPKESYVKSVIQSKEGGKVTVK-TESGATLTVKEDQVFPMNPPKYDKIEDMAMMTHL 99
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 100 HEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVAAYRGKKRQEAPPHIFS 159
Query: 448 IADTAYRSMLQ-------EREDQSILCT-----GESGAGKTENTKKVIQYLAHVAGATRN 591
I+D AY+ ML R S L + GESGAGKT NTK+VIQY A +A
Sbjct: 160 ISDNAYQFMLTASVLTIASRSHHSELLSLMFNSGESGAGKTVNTKRVIQYFATIAVTGEK 219
Query: 592 KSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINF 771
K + Q G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F
Sbjct: 220 KKEESGKMQ------------GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHF 267
Query: 772 DMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYR 945
+G ++ A+IE YLLEKSRV Q + ERS+HIFYQI E E LL + +Y
Sbjct: 268 GTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSN-KKPELIEMLLITTNPYDYA 326
Query: 946 FLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSD 1125
F+ IT+P++DD +E +T +++ I+GF+ +E SI ++ AV+ GN++F Q+++ +
Sbjct: 327 FVSQGEITVPSIDDQEELMATDSAIDILGFSPEEKVSIYKLTGAVMHYGNMKFKQKQREE 386
Query: 1126 QAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKAS 1305
QA V K +L L +L KA PR+KVG E+V K Q +Q AV A+AKA
Sbjct: 387 QAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAV 446
Query: 1306 YERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFN 1485
YE++F W+VTRIN+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN
Sbjct: 447 YEKMFLWMVTRINQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFN 505
Query: 1486 NTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVE 1665
+ MF+LEQEEY++EGIEW FIDFG+DL I+LIEKP+G+ ++L+EEC+FPKA D SF
Sbjct: 506 HHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSFKN 565
Query: 1666 KLQKTH-NKHPKFIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQ 1833
KL H K F P ++++HF+++HYAG VDY+ WL KN DPLN+ VVGL Q
Sbjct: 566 KLYDQHLGKSNNFQKPKPTKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQ 625
Query: 1834 NSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTS 2013
S +A ++ A + GM ++ G + E L KLMT LR+T
Sbjct: 626 KSAMKTLASLFSTYASAEAEHEIIRMLMVGMIAKLGFHWNLPA--TENLNKLMTNLRSTH 683
Query: 2014 PHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILT 2193
PHFVRCIIPN K G + LVL QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L
Sbjct: 684 PHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLN 743
Query: 2194 PDVIPK-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIM 2370
IP+ FID K++ K++ ++DID Y+ G +KVFF+ G+L LEE RD KL +I
Sbjct: 744 ASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIIT 803
Query: 2371 NFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTD 2550
QA CRG+L R Y N A++ +++W W +LF K+KPLL+ T+
Sbjct: 804 RTQAVCRGYLMRVEYQKMLLRRESIFCIQYNIRAFMNVKHWPWMKLFFKIKPLLKSAETE 863
Query: 2551 DEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRG 2730
E+ +E + TK+ L K E +E E+K+ ++ E+ +Q Q+Q E+++ A+ ++
Sbjct: 864 KEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCE 923
Query: 2731 RLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXX 2910
+L +LE + ++ +R +RK + +
Sbjct: 924 QLIKNKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEK 983
Query: 2911 DKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGR 3090
+K + + L E++ KAK +
Sbjct: 984 EKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTK 1043
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
LE Q+ +LE L +E++ + +LE+ KRKL +L+ +++ + ++L+ +L K++ E
Sbjct: 1044 LEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFE 1103
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ + +++ ++E A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++
Sbjct: 1104 ISNLISKIEDEQAVEIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEI 1163
Query: 3451 KGDVLDKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+ L++ AT Q +L +++ E +R +E+ E + K + + EL +
Sbjct: 1164 -SERLEEAGGATSAQVELNKKRETEFQKLRRDLEEATLQHEATSAALRKKHADSMAELGE 1222
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAE 3807
QI+ ++ + +LEK++++ E D++ + ++ +++K + E + E+++ E
Sbjct: 1223 QIDNLQRVKQKLEKEKSELKMEIDDLSSNAEAIAKAKGNLEKMCRTLEDQVSELKSKEEE 1282
Query: 3808 SDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL 3987
L Q R + E +R +E++ + + R + T+
Sbjct: 1283 QQRLINELTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKRQLEEETKA 1342
Query: 3988 KIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEE 4167
K A + + + + L ++ EE + +A L++ + A + R K E Q+ EE
Sbjct: 1343 KNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEE 1402
Query: 4168 LRKKNLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKR 4338
L + + + LQ E E + + ++K+++Q E+ED +++E A+ +K+
Sbjct: 1403 LEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKK 1462
Query: 4339 QKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSL 4518
Q+ F+ ++E R ++ + ++ +E R T + + N + + LE R ++L
Sbjct: 1463 QRNFDKVLSEWRQKYEETQAELESCQKESRTLSTELFKVKNAYEESLDQLETLRRENKNL 1522
Query: 4519 QQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTN 4698
QQE+ D + GK++HELEK K+ +E E +++ +EE E +L+ E LR+++
Sbjct: 1523 QQEISDLTEQIAEGGKHIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLEL 1582
Query: 4699 QALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGEL 4878
+KSE DR I+ KD E ++ +R ++ + +++ L+ E R ++ A+ +KK+E + E+
Sbjct: 1583 NQVKSEIDRKIAEKDEEIDQLKRNHIRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEM 1642
Query: 4879 EQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAER 5058
E QL ANRL E + Q+ ++A + +ED+ L +R+ ++AE
Sbjct: 1643 EIQLNHANRLAAESLRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEI 1702
Query: 5059 EQLREANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQ 5229
E+LR E ++RK Q K++LE ++Q
Sbjct: 1703 EELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVI 1762
Query: 5230 SNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQ 5409
A +K +KA + +L E+ + E K++LE++ +D + ++ E E A
Sbjct: 1763 QESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLAL 1822
Query: 5410 SRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAK 5589
+ Q+ LEA+V+ LE ++ E + A + R+ E+R+ + T Q E++++ + +
Sbjct: 1823 KGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQ 1882
Query: 5590 ELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+L++K K ++ +RQ +EAE++ + K R +Q E ++
Sbjct: 1883 DLVDKLQAKVKSYKRQAEEAEEQSNVNLAKFRKLQHELEE 1922
Score = 168 bits (425), Expect = 2e-39
Identities = 182/947 (19%), Positives = 413/947 (43%), Gaps = 49/947 (5%)
Frame = +1
Query: 3040 LLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKL-------------- 3177
L D EER + +K K +LE ++ E+ + E + +EL KRKL
Sbjct: 915 LADAEERCEQLIKNKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL 974
Query: 3178 ---LAELEDSK-------DHLAEKMGKVEELNNQLMKRDEELQ--HQLTRYD--EESANV 3315
LA++E K +L E+M ++E +L K + LQ HQ T D E V
Sbjct: 975 ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKV 1034
Query: 3316 TLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ 3495
+ K ++ +D+L +E E+ R E +R++ L+ + +D ++ L
Sbjct: 1035 NTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDIENDKQQLD 1094
Query: 3496 DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQ 3675
+ + +K+ E++ IE + +E +++++ + ++EEL ++IE + R++ EKQ+
Sbjct: 1095 EKLKKKEFEISNLISKIED-EQAVEIQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1153
Query: 3676 NQADQERADMA---QEIALLQASRADIDKKRKIHEAHLMEIQANLAESD-EHKRTL---- 3831
+ +E +++ +E +++ +++KKR E +++ +L E+ +H+ T
Sbjct: 1154 SDLSRELEEISERLEEAGGATSAQVELNKKR---ETEFQKLRRDLEEATLQHEATSAALR 1210
Query: 3832 ---IDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANI 4002
D + +++D+L RV+++ E + ++ + ++
Sbjct: 1211 KKHADSMAELGEQIDNLQRVKQKLEKEKSELKMEIDDLSSNAEAIAKAKGNLEKM----- 1265
Query: 4003 NRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEE--SVNQQLEELRK 4176
R LED+ + L ++EE + L L + + AGE R+ +E ++ QL ++
Sbjct: 1266 --CRTLEDQVSELKSKEEEQQRLINELTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQ 1323
Query: 4177 KNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFES 4356
+ + +E L++QLEE AK + + + + + + + E + + ++ K S
Sbjct: 1324 ASTQQIEELKRQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANS 1383
Query: 4357 QMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNE-VDIMKEHLEESDRVRRSLQQELQ 4533
++A+ R + + R +E + + + L E V+ + ++ ++ LQ E++
Sbjct: 1384 EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVE 1443
Query: 4534 DSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKS 4713
D + + + L+K +R+ + L++ R + EE + L+ + L +K+
Sbjct: 1444 DLMLDVERTNAACAALDKKQRNFDKVLSEWRQKYEETQAELESCQKESRTLSTELFKVKN 1503
Query: 4714 ESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLE 4893
+ ++ + E + L ++I DL ++ + +K++E + E++ LE
Sbjct: 1504 AYEESLDQLETLRRE-NKNLQQEISDLTEQIAEGGKHIHELEKIKKQVEQEKCEIQAALE 1562
Query: 4894 VANRLKEEYXXXXXXXXXXXXEYQIECEEAR--QAKEDIAALLREADRKFRAVEAEREQL 5067
A E +E EE + + + ++ + E DRK + E +QL
Sbjct: 1563 EA-------------------EASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQL 1603
Query: 5068 REANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELA 5247
+ + +++ + R++ + K+++E + + +
Sbjct: 1604 KRNHIRVVETMQ-----STLDAEIRSRNDAL--RVKKKMEGDLNEMEIQLNHANRLAAES 1656
Query: 5248 IDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQ--SLERSNRDYKAKITELESGAQSRAR 5421
+ R Q L+ T L ++ L + + ++Q +ER +A+I EL + + R
Sbjct: 1657 LRNYRNTQGILKD--TQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELRATLEQTER 1714
Query: 5422 AQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLE 5601
++ A E ++ +++ + + T+ ++LE ++ + E+ + + A+E +
Sbjct: 1715 SRKIA-EQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAK 1773
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL---LDANEQL 5733
K+ + +L + +D + +N+++ DL LD EQL
Sbjct: 1774 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQL 1820
Score = 153 bits (387), Expect = 4e-35
Identities = 185/923 (20%), Positives = 385/923 (41%), Gaps = 37/923 (4%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + + + +L + + ELE+ LL E D + + A+ + EE
Sbjct: 864 KEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCE 923
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE N L K+ R ++ EL++D++ E
Sbjct: 924 QLIKNKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKDIDD-------LE 975
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E L + +++ +E A + A +Q ++ +
Sbjct: 976 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1035
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIAL-LQASRADID 3750
+ + K K +QV++L +EQ KK R LE+ + + + + +AQE + ++ + +D
Sbjct: 1036 TLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGD-LKLAQESTMDIENDKQQLD 1094
Query: 3751 KKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLA 3930
+K K E + +NL E ++ + QL++ EL R+ E EE A R
Sbjct: 1095 EKLKKKEFEI----SNLISKIEDEQAVEIQLQKKIKELQ--ARIEELEEEIEAERASR-- 1146
Query: 3931 TAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQ 4110
+ + + +R+LE+ + E+ E G + E++ R+
Sbjct: 1147 ----------------AKAEKQRSDLSRELEE-----ISERLEEAGGATSAQVELNKKRE 1185
Query: 4111 GAGEARRKAEESVNQQLE----ELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
+ R+ E Q E LRKK+ + L +Q++ + K+++ + K +++ E+
Sbjct: 1186 TEFQKLRRDLEEATLQHEATSAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMEI 1245
Query: 4279 EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLL 4458
+D S E + + + EK + E Q++E + + ++ + EL + R L
Sbjct: 1246 DDLSSNAEAIAKAKGNLEKMCRTLEDQVSELKSKEE----EQQRLINELTAQRAR---LQ 1298
Query: 4459 NEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQME 4638
E L+E D + L + Q S ++ + + E KAK +L L R +
Sbjct: 1299 TEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKRQLEEETKAKNALAHALQSSRHDCD 1358
Query: 4639 ELEDNLQIAEDARLRL---------EVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRD 4791
L + + ++ + L EV K E+D AI + E EE ++ L ++++
Sbjct: 1359 LLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETD-AIQRTE-ELEEAKKKLAQRLQA 1416
Query: 4792 LENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIE 4971
E +E + +++++N++ +L +E N E++ +
Sbjct: 1417 AEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKVLSEWRQK 1476
Query: 4972 CEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKG 5151
EE + E R + V+ E+ + E L + K A+G
Sbjct: 1477 YEETQAELESCQKESRTLSTELFKVKNAYEESLDQLETLRRENKNLQQEISDLTEQIAEG 1536
Query: 5152 GGISSE---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLN 5322
G E K+++E + + +++ E K + Q++L Q+ ++ ++
Sbjct: 1537 GKHIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSE------ID 1590
Query: 5323 QKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAK------VQYLEDQLNVEG 5484
+K + + +++ R++ + ++S + R++ AL K + +E QLN
Sbjct: 1591 RKIAEKDEEIDQLKRNHIRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHAN 1650
Query: 5485 QEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMS 5664
+ + R R + L DT +D R E KE L + L+ +++E +
Sbjct: 1651 RLAAESLRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELRATLE 1710
Query: 5665 RERTKHRNVQREADDLLDANEQL 5733
+ + ++E LLDA+E++
Sbjct: 1711 QTERSRKIAEQE---LLDASERV 1730
Score = 116 bits (291), Expect = 6e-24
Identities = 181/898 (20%), Positives = 357/898 (39%), Gaps = 121/898 (13%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ +E + +E+D ++ ++KL + E + + +++ E +L LQ
Sbjct: 1070 RKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEISNLISKIEDEQAVEIQLQKKIKELQ 1129
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + +R S R ++E + + +
Sbjct: 1130 ARIEELEEEIE--AERASRAKAEKQRSDLSR--ELEEISERLEEAGGATSAQVELNKKRE 1185
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K L+
Sbjct: 1186 TEFQKLRRDLEEATLQHEATSAALRKKHADSMAELG---EQIDNLQRVKQKLEKEKSELK 1242
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L + + K LE K+ LED L K + + L N+L + LQ
Sbjct: 1243 MEIDDLSSNAEAIAKAKGNLE----KMCRTLEDQVSELKSKEEEQQRLINELTAQRARLQ 1298
Query: 3277 HQLTRY----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLE 3444
+ Y DE+ A V+ + + + I+EL+ +E E A+N + +
Sbjct: 1299 TEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKRQLEEETKAKNALAHALQSSRHDCD 1358
Query: 3445 KVKGDVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEE 3618
++ ++ + LQ +S+ + EV TK + IQ T E +EE K K +++++
Sbjct: 1359 LLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQA 1416
Query: 3619 LHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME---- 3786
+ +E + + LEK + + E D+ ++ A+ A +DKK++ + L E
Sbjct: 1417 AEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKVLSEWRQK 1476
Query: 3787 ---IQANLAESDEHKRTL--------------IDQLERSRDE------------------ 3861
QA L + RTL +DQLE R E
Sbjct: 1477 YEETQAELESCQKESRTLSTELFKVKNAYEESLDQLETLRRENKNLQQEISDLTEQIAEG 1536
Query: 3862 ---LDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEK 4032
+ L +++++ E +Q L A R+++ +N+ + D K
Sbjct: 1537 GKHIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKIL---RIQL-ELNQVKSEIDRK 1592
Query: 4033 NALLDEKEE---------AEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN- 4182
A DE+ + E +++ L+ EI + R A ++K E +N+ +L N
Sbjct: 1593 IAEKDEEIDQLKRNHIRVVETMQSTLDAEIRS-RNDALRVKKKMEGDLNEMEIQLNHANR 1651
Query: 4183 -----LRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSM-------ELENVRASHRD 4326
LR+ + Q L+++++ + L+ ++ ++++L E+E +RA+
Sbjct: 1652 LAAESLRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELRATLEQ 1711
Query: 4327 SEKRQKKFESQM--AEERVAV----------QKALLDRDAMS---------QELRDRETR 4443
+E+ +K E ++ A ERV + K L+ D QE R+ E +
Sbjct: 1712 TERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEK 1771
Query: 4444 VLSLLNEVDIMKEHLEES-------DRVRRSLQQELQDSISNKDDFG--------KNVHE 4578
+ + +M E L++ +R++++L+Q ++D D+ K + +
Sbjct: 1772 AKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK 1831
Query: 4579 LEKAKRSLEAELNDMRVQMEELEDNL------------QIAEDAR--LRLEVTNQALKSE 4716
LE R LE E+ + + + E L Q ED + LRL+ L+++
Sbjct: 1832 LEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAK 1891
Query: 4717 SDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
++ + EAEE+ L + R L++ELE + A S K+ + E+ ++
Sbjct: 1892 V-KSYKRQAEEAEEQSNVNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKI 1948
Score = 93.2 bits (230), Expect = 7e-17
Identities = 96/493 (19%), Positives = 204/493 (40%), Gaps = 20/493 (4%)
Frame = +1
Query: 2968 QDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYK 3147
++AY+ L ++ D E+ G K +HELE+ K
Sbjct: 1502 KNAYEESLDQLETLRRENKNLQQEISDLTEQIAEGGK-------HIHELEK-------IK 1547
Query: 3148 SELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQ 3327
++EQ K ++ A LE+++ L + GK+ + +L + E+ ++ DEE +
Sbjct: 1548 KQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEE------ID 1601
Query: 3328 KQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMS 3507
+ R+ ++ ++ ++ E +RN A ++ K++GD+ + + L +
Sbjct: 1602 QLKRNHIRVVETMQSTLDAEIRSRNDALRVKK-------KMEGDLNEMEIQLNHANRLAA 1654
Query: 3508 RKDEEVNATKRAIEQIQHTMEGKI------EEQKAKFSRQVEELHDQIEQHKKQRSQLEK 3669
T+ ++ Q ++ + +EQ A R+ L +IE+ + Q E+
Sbjct: 1655 ESLRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELRATLEQTER 1714
Query: 3670 QQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRT------- 3828
+ A+QE D ++ + LL + +K E + ++Q+ + E + R
Sbjct: 1715 SRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKK 1774
Query: 3829 -------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL 3987
+ ++L++ +D HL R+++ E ++Q RL A
Sbjct: 1775 AITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEA 1834
Query: 3988 KIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEE 4167
++ + + E ++NA E +GLR H E+ + E R+ +L++
Sbjct: 1835 RVRELEGEVENEQKRNA-----EAVKGLRKH-ERRVKELTYQTEEDRKNV-----LRLQD 1883
Query: 4168 LRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKK 4347
L K V+ ++Q EE+E L +K+Q ELE++ RA +S+ + +
Sbjct: 1884 LVDKLQAKVKSYKRQAEEAEEQSNVNLAKFRKLQHELEEA-----EERADIAESQVNKLR 1938
Query: 4348 FESQMAEERVAVQ 4386
+S+ +++ +
Sbjct: 1939 VKSREVHTKISAE 1951
Score = 78.6 bits (192), Expect = 2e-12
Identities = 73/372 (19%), Positives = 163/372 (43%), Gaps = 12/372 (3%)
Frame = +1
Query: 4654 LQIAEDARLRLEVTNQALKSESDRAISN-KDVEAEEKRRGLLKQIRDLENELENEKRGKS 4830
L+ AE + + + K++ + A S K E EEK LLK+ DL+ ++++E +
Sbjct: 857 LKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLA 916
Query: 4831 GAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAA 5010
A +++ +LE +++ E+ + + EC E ++ +D+
Sbjct: 917 DAEERCEQLIKNKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLEL 976
Query: 5011 LLREADRKFRAVEAEREQLREANEGLMQA-RKQXXXXXXXXXXXRAKGGGISSEEKRRLE 5187
L + +++ A E + + L E GL + K + + +EE +
Sbjct: 977 TLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK--V 1034
Query: 5188 AKIAQXXXXXXXXQSNCELAIDKQRKAQVQLE----QITTDLSMERTLNQKTEAEKQSLE 5355
+ + + E ++++++K ++ LE ++ DL + + E +KQ L+
Sbjct: 1035 NTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDIENDKQQLD 1094
Query: 5356 RSNRDYKAKITEL------ESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAAR 5517
+ + +I+ L E + + + ++ L+A+++ LE+++ E + A +
Sbjct: 1095 EKLKKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS 1154
Query: 5518 RLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQR 5697
L + L + +++ E+ A EL +K + + LRR L+EA + E T ++
Sbjct: 1155 DLSRELEEISERLEEAGGATSAQVELNKKRETEFQKLRRDLEEA--TLQHEATSAALRKK 1212
Query: 5698 EADDLLDANEQL 5733
AD + + EQ+
Sbjct: 1213 HADSMAELGEQI 1224
>gi|34870888|ref|XP_340819.1| similar to myosin heavy chain 2b [Rattus
norvegicus]
Length = 2009
Score = 1068 bits (2763), Expect = 0.0
Identities = 642/1912 (33%), Positives = 1044/1912 (54%), Gaps = 58/1912 (3%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V D E ++ +++ +V + + VT+ D V NPPK+DKIEDM+ +T+L
Sbjct: 39 FVVDAKESYVKATVQSREGGKVTAK-TEGGATVTVKEDQVFSMNPPKYDKIEDMAMMTHL 97
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 98 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVAAYRGKKRQEAPPHIFS 157
Query: 448 IADTAYRSMLQE-----------------------REDQSILCTGESGAGKTENTKKVIQ 558
I+D AY+ ML E RE+QSIL TGESGAGKT NTK+VIQ
Sbjct: 158 ISDNAYQFMLTEEHNFISVCAFVYLVYVFFFLFTDRENQSILITGESGAGKTVNTKRVIQ 217
Query: 559 YLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNS 738
Y A +A T +K A + G LE Q++ ANP+LEAFGN+KTV+NDNS
Sbjct: 218 YFATIA-VTGDKKKEEAPSGKMQ---------GTLEDQIISANPLLEAFGNAKTVRNDNS 267
Query: 739 SRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEY 918
SRFGKFIRI+F +G ++ A+IE YLLEKSRV Q + ERS+HIFYQ++ E E
Sbjct: 268 SRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQVMSN-KKPELIEM 326
Query: 919 LLEGVDNYRFL-VNRG-ITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 1092
LL + Y F V++G IT+P++DD +E +T ++ I+GF DE +I ++ AV+ G
Sbjct: 327 LLITTNPYDFAYVSQGEITVPSIDDQEELMATDTAVDILGFTADEKVAIYKLTGAVMHYG 386
Query: 1093 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA 1272
N++F Q+++ +QA V K +L L +L KA PR+KVG E+V K Q +Q
Sbjct: 387 NMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKALCYPRVKVGNEYVTKGQTVQQV 446
Query: 1273 EFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICIN 1452
+V A+AKA YE++F W+VTRIN+ LD T + FIG+LDIAGFEIFD N+ EQ+CIN
Sbjct: 447 YNSVGALAKAMYEKMFLWMVTRINQQLD-TKQPRQYFIGVLDIAGFEIFDFNTLEQLCIN 505
Query: 1453 YTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECL 1632
+TNEKLQQ FN+ MF+LEQEEY++EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+
Sbjct: 506 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECM 565
Query: 1633 FPKANDKSFVEKLQKTH-NKHPKFIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMD 1800
FPKA D SF KL + H K F P ++++HF++VHYAG VDY+ WL KN D
Sbjct: 566 FPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIIGWLDKNKD 625
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAEFAG---------------ICAAEMNETAFGMRSR 1935
PLNE VVGL Q S +A ++ + A I A E+ + G +
Sbjct: 626 PLNETVVGLYQKSGLKTLAFLFSGGQAAEAVSKVTSVMTVSSSIIEADELWKKEEGGGGK 685
Query: 1936 KG------MFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLR 2097
KG F+TVS L +E L KLMT L++T PHFVRC+IPN K G + LVL QLR
Sbjct: 686 KGGKKKGSSFQTVSALFRENLNKLMTNLKSTHPHFVRCLIPNETKTPGAMEHELVLHQLR 745
Query: 2098 CNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDGKESVRKMITALDIDTN 2274
CNGVLEGIRICR+GFP+R+ + +F+ RY++L IP+ FID K++ K++ ++DID
Sbjct: 746 CNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHT 805
Query: 2275 LYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXX 2454
Y+ G +KVFF+ G+L LEE RD KL LI QA CRG+L R +
Sbjct: 806 QYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAVCRGYLMRVEFRKMMERRESIFCI 865
Query: 2455 XXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENE 2634
N A++ +++W W +L+ K+KPLL+ T+ E+ ++ KE L K E +E E
Sbjct: 866 QYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMATMKEDFEKAKEDLAKSEAKRKELE 925
Query: 2635 KKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXX 2814
+K+ ++ E+ +Q Q+Q E++ A+ ++ +L +LE + ++ +R
Sbjct: 926 EKMVALMQEKNDLQLQVQAEADGLADAEERCDQLIKTKIQLEAKIKELTERAEDEEEINA 985
Query: 2815 XXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXX 2994
+RK + + +K + +
Sbjct: 986 ELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDENIAKLTK 1045
Query: 2995 XXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRK 3174
L E++ KAK +LE Q+ +LE L +E++ + +LE+ KRK
Sbjct: 1046 EKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRK 1105
Query: 3175 LLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTT 3354
L +L+ +++ + ++L+ +L K++ E+ + ++ ++E A +QK+++++Q
Sbjct: 1106 LEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDEQALGMQLQKKIKELQAR 1165
Query: 3355 IDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDE-EVNA 3531
I+EL E++E ER +R KAE R ++ +LE++ + L++ AT Q M++K E E
Sbjct: 1166 IEELEEEIEAERASRAKAEKQRSDLSRELEEI-SERLEEAGGATSAQIEMNKKREAEFQK 1224
Query: 3532 TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQ 3711
+R +E+ E + K + V EL +QI+ ++ + +LEK++++ E D+A
Sbjct: 1225 MRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDLAS 1284
Query: 3712 EIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREE 3891
+ + ++ +++K + E L E++ E L Q R E +R +E
Sbjct: 1285 NMETVSKAKGNLEKMCRTLEDQLSEVKTKEEEQQRLINELSAQKARLHTESGEFSRQLDE 1344
Query: 3892 EEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGL 4071
++ + + R ++ K A + + + + L ++ EE +
Sbjct: 1345 KDAMVSQLSRGKQAFTQQIEELKRQLEEESKAKNALAHALQSARHDCDLLREQYEEEQEA 1404
Query: 4072 RAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKER--- 4242
+A L++ + A + R K E Q+ EEL + + + LQ E E +
Sbjct: 1405 KAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCAS 1464
Query: 4243 ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQE 4422
+ ++K+++Q E+ED +++E A+ +K+Q+ F+ +AE + ++ + +A +E
Sbjct: 1465 LEKTKQRLQNEVEDLMIDVERSNAACAALDKKQRNFDKVLAEWKQKYEETQAELEASQKE 1524
Query: 4423 LRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSL 4602
R T + + N + + LE R ++LQQE+ D + GK++HELEK K+ +
Sbjct: 1525 SRSLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKIKKQI 1584
Query: 4603 EAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQ 4782
+ E ++++ +EE E +L+ E LR+++ +KSE DR I+ KD E ++ +R L+
Sbjct: 1585 DQEKSELQASLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKRNHLRV 1644
Query: 4783 IRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEY 4962
+ +++ L+ E R ++ A+ +KK+E + E+E QL ANR E +
Sbjct: 1645 VESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEAIRNLRNTQGMLKDT 1704
Query: 4963 QIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARK---QXXXXXXXXX 5133
Q+ ++A + ++D+ L +R+ ++AE E+LR + E ++R+ Q
Sbjct: 1705 QLHLDDALRGQDDLKEQLAMVERRANLMQAEIEELRASLEQTERSRRVAEQELLDASERV 1764
Query: 5134 XXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMER 5313
K++LE I+Q A +K +KA + +L E+
Sbjct: 1765 QLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQ 1824
Query: 5314 TLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEK 5493
+ E K+++E++ +D + ++ E E A + Q+ LEA+V+ LE+++ E +
Sbjct: 1825 DTSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELENEVENEQKRN 1884
Query: 5494 TAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEA 5649
A + R+ E+R+ + T Q E++++ + ++L++K K + +RQ +EA
Sbjct: 1885 IEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQTKVKAYKRQAEEA 1936
Score = 165 bits (417), Expect = 1e-38
Identities = 187/930 (20%), Positives = 390/930 (41%), Gaps = 44/930 (4%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + ++DL + + ELE+ L+ E D + + A+ + EE +
Sbjct: 898 KEMATMKEDFEKAKEDLAKSEAKRKELEEKMVALMQEKNDLQLQVQAEADGLADAEERCD 957
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE N L K+ R ++ EL++D++ E
Sbjct: 958 QLIKTKIQLEAKIKELTERAEDEEEINAELTAKK-RKLEDECSELKKDIDD-------LE 1009
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E L + +++ +E A + A +Q ++ +
Sbjct: 1010 LTLAKVEKEKHATENKVKNLTEEMAGLDENIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1069
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIAL-LQASRADID 3750
+ + K K +QV++L +EQ KK R LE+ + + + + +AQE + ++ + +D
Sbjct: 1070 TLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGD-LKLAQESTMDIENDKQQLD 1128
Query: 3751 KKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLA 3930
+K K E + +Q+ + E ++ L QL++ EL R+ E EE A R
Sbjct: 1129 EKLKKKEFEMSNLQSKI----EDEQALGMQLQKKIKELQ--ARIEELEEEIEAERASRAK 1182
Query: 3931 TAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQ 4110
RL+ A + Q+E +++K EAE
Sbjct: 1183 AEKQRSDLSRELEEISERLEEAGGATSAQIE------MNKKREAE--------------- 1221
Query: 4111 GAGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELE 4281
+ RR EE+ Q LRKK+ V L +Q++ + K+++ + K +++ E++
Sbjct: 1222 -FQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSELKMEID 1280
Query: 4282 DSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLN 4461
D + +E V + + EK + E Q++E + + ++ + EL ++ R L
Sbjct: 1281 DLASNMETVSKAKGNLEKMCRTLEDQLSEVKTKEE----EQQRLINELSAQKAR---LHT 1333
Query: 4462 EVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE 4641
E L+E D + L + Q ++ + + E KAK +L L R +
Sbjct: 1334 ESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEESKAKNALAHALQSARHDCDL 1393
Query: 4642 LEDNLQIAEDARLRL---------EVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDL 4794
L + + ++A+ L EV K E+D AI + E EE ++ L ++++D
Sbjct: 1394 LREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETD-AIQRTE-ELEEAKKKLAQRLQDA 1451
Query: 4795 ENELENEKRGKSGAVSHRKKIENQIGELEQQLEVAN-------RLKEEYXXXXXXXXXXX 4953
E +E + +++++N++ +L +E +N + + +
Sbjct: 1452 EEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACAALDKKQRNFDKVLAEWKQKY 1511
Query: 4954 XEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXX 5133
E Q E E +++ ++ L + + + E L+ N+ L Q
Sbjct: 1512 EETQAELEASQKESRSLSTELFKVKNAYEESLDQLETLKRENKNLQQ--------EISDL 1563
Query: 5134 XXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQR----KAQVQLEQITTDL 5301
+ GG E +++ +I Q E +++ + + Q++L Q+ ++
Sbjct: 1564 TEQIAEGGKHIHELEKIKKQIDQEKSELQASLEEAEASLEHEEGKILRIQLELNQVKSE- 1622
Query: 5302 SMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAAL------EAKVQYLE 5463
+++K + + +++ R++ + ++S + R++ AL E + +E
Sbjct: 1623 -----IDRKIAEKDEEIDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEME 1677
Query: 5464 DQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLD 5643
QLN ++ A R R + L DT +D R + KE L + ++ +++
Sbjct: 1678 IQLNHANRQAAEAIRNLRNTQGMLKDTQLHLDDALRGQDDLKEQLAMVERRANLMQAEIE 1737
Query: 5644 EAEDEMSRERTKHRNVQREADDLLDANEQL 5733
E + + R ++E LLDA+E++
Sbjct: 1738 ELRASLEQTERSRRVAEQE---LLDASERV 1764
Score = 124 bits (312), Expect = 2e-26
Identities = 133/754 (17%), Positives = 314/754 (41%), Gaps = 43/754 (5%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A E+ + + + + +R +LE++ QE+ D+ ++ AD ++
Sbjct: 897 EKEMATMKEDFEKAKEDLAKSEAKRKELEEKMVALMQEKNDLQLQVQAEADGLADAEERC 956
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ + +E L + + DE L + ++ E A ++
Sbjct: 957 DQLIKTKIQLEAKIKELTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 1016
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ T K+ N+ DE A L ++++A +
Sbjct: 1017 KE---------------KHATENKVKNLTEEMAGLDENIAKLTKEKKA----------LQ 1051
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
A Q + + E+ VN L + + K + V+ L+ LE+ + + + ++K+K++ +L
Sbjct: 1052 EAHQQTLDDLQAEEDKVNT-LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDL 1110
Query: 4279 ---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL 4449
++S+M++EN + D + ++K+FE + ++ ++AL + +++++ + R+
Sbjct: 1111 KLAQESTMDIENDK-QQLDEKLKKKEFEMSNLQSKIEDEQAL--GMQLQKKIKELQARIE 1167
Query: 4450 SLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRV 4629
L E++ + ++++ R L +EL++ ++ G + + EAE MR
Sbjct: 1168 ELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR 1227
Query: 4630 QME----------------------ELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
+E EL + + + + +LE LK E D SN +
Sbjct: 1228 DLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNME 1287
Query: 4744 VEAEEKRRGLLKQIRDLENEL-------ENEKRGKSGAVSHRKKIENQIGELEQQLEVAN 4902
++ K L K R LE++L E ++R + + + ++ + GE +QL+ +
Sbjct: 1288 TVSKAK-GNLEKMCRTLEDQLSEVKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKD 1346
Query: 4903 RLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA----DRKFRAVEAEREQLR 5070
+ + E + + EE +AK +A L+ A D E E+E
Sbjct: 1347 AMVSQLSRGKQAFTQQIEELKRQLEEESKAKNALAHALQSARHDCDLLREQYEEEQEAKA 1406
Query: 5071 EANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAI 5250
E + +A + + E K++L ++ S C
Sbjct: 1407 ELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLE 1466
Query: 5251 DKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQM 5430
+++ Q ++E + D+ + ++++ ++ ++K K E ++ ++ ++ +
Sbjct: 1467 KTKQRLQNEVEDLMIDVERSNAACAALDKKQRNFDKVLAEWKQKYEETQAELEA-SQKES 1525
Query: 5431 AALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSN 5610
+L ++ +++ + R + L++ ++D T+Q + + + +++ ++ +
Sbjct: 1526 RSLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKIKKQID 1585
Query: 5611 LKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ L+ L+EAE + E K +Q E + +
Sbjct: 1586 QEKSELQASLEEAEASLEHEEGKILRIQLELNQV 1619
Score = 73.2 bits (178), Expect = 7e-11
Identities = 109/521 (20%), Positives = 197/521 (36%), Gaps = 18/521 (3%)
Frame = +1
Query: 4234 KERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAM 4413
K + L + ++E+ + E + SE ++K+ E +M L A
Sbjct: 886 KIKPLLKSAETEKEMATMKEDFEKAKEDLAKSEAKRKELEEKMVALMQEKNDLQLQVQAE 945
Query: 4414 SQELRDRETRVLSLLN-------EVDIMKEHLEESDRV-------RRSLQQELQDSISNK 4551
+ L D E R L+ ++ + E E+ + + +R L+ E + +
Sbjct: 946 ADGLADAEERCDQLIKTKIQLEAKIKELTERAEDEEEINAELTAKKRKLEDECSELKKDI 1005
Query: 4552 DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQA----LKSES 4719
DD + ++EK K + E ++ ++ +M L++N+ + L+ +Q L++E
Sbjct: 1006 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDENIAKLTKEKKALQEAHQQTLDDLQAEE 1065
Query: 4720 DRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
D+ N +A+ K L +Q+ DLE LE EK+ R +E +LE L++A
Sbjct: 1066 DKV--NTLTKAKTK---LEQQVDDLEGSLEQEKK-------LRMDLERAKRKLEGDLKLA 1113
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREAN 5079
+ + + E + ED AL + +K + ++A E+L E
Sbjct: 1114 QESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDEQALGMQLQKKIKELQARIEELEEEI 1173
Query: 5080 EGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQ 5259
E RAK S+ R LE
Sbjct: 1174 EA--------------ERASRAKAEKQRSDLSRELE------------------------ 1195
Query: 5260 RKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAAL 5439
+ +LE+ S + +N+K EAE Q + R +LE A + A AAL
Sbjct: 1196 -EISERLEEAGGATSAQIEMNKKREAEFQKMRR----------DLEE-ATLQHEATAAAL 1243
Query: 5440 EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKN 5619
K D + G++ R ++LEK ++ + +D +E +
Sbjct: 1244 RKK---HADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDD-------LASNMETVSKAK 1293
Query: 5620 RNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
NL + ED++S +TK QR ++L +L E
Sbjct: 1294 GNLEKMCRTLEDQLSEVKTKEEEQQRLINELSAQKARLHTE 1334
>gi|3660083|pdb|1BR1|A Chain A, Smooth Muscle Myosin Motor
Domain-Essential Light Chain Complex With Mgadp.Alf4
Bound At The Active Site
gi|3660085|pdb|1BR1|C Chain C, Smooth Muscle Myosin Motor
Domain-Essential Light Chain Complex With Mgadp.Alf4
Bound At The Active Site
gi|3660087|pdb|1BR1|E Chain E, Smooth Muscle Myosin Motor
Domain-Essential Light Chain Complex With Mgadp.Alf4
Bound At The Active Site
gi|3660089|pdb|1BR1|G Chain G, Smooth Muscle Myosin Motor
Domain-Essential Light Chain Complex With Mgadp.Alf4
Bound At The Active Site
gi|3660097|pdb|1BR4|A Chain A, Smooth Muscle Myosin Motor
Domain-Essential Light Chain Complex With Mgadp.Bef3
Bound At The Active Site
gi|3660099|pdb|1BR4|C Chain C, Smooth Muscle Myosin Motor
Domain-Essential Light Chain Complex With Mgadp.Bef3
Bound At The Active Site
gi|3660101|pdb|1BR4|E Chain E, Smooth Muscle Myosin Motor
Domain-Essential Light Chain Complex With Mgadp.Bef3
Bound At The Active Site
gi|3660103|pdb|1BR4|G Chain G, Smooth Muscle Myosin Motor
Domain-Essential Light Chain Complex With Mgadp.Bef3
Bound At The Active Site
Length = 820
Score = 1065 bits (2754), Expect = 0.0
Identities = 529/811 (65%), Positives = 653/811 (80%), Gaps = 8/811 (0%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
D ++L V + V +P A W+ +KL WVP + GF SIK E DEV VEL + ++V
Sbjct: 8 DEKFLFVDKNFVNNPLAQADWSAKKLVWVPSEKHGFEAASIKEEKGDEVTVELQENGKKV 67
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
T+S+DD+QK NPPKF K+EDM+ELT LNEASVLHNL++RY+S LIYTYSGLFCVVINPYK
Sbjct: 68 TLSKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVINPYK 127
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
+LPIYSE +I+ +KGKKRHEMPPHI+AIADTAYRSMLQ+REDQSILCTGESGAGKTENTK
Sbjct: 128 QLPIYSEKIIDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTK 187
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVIQYLA VA + + K +I Q P GELE QLLQANPILEAFGN+KTVK
Sbjct: 188 KVIQYLAVVASSHKGKK-----DTSITQGPSFS--YGELEKQLLQANPILEAFGNAKTVK 240
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
NDNSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFY ++ G S +
Sbjct: 241 NDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQAKDERTFHIFYYLIAGASEQM 300
Query: 907 KSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLL 1086
+++ LLEG +NY FL N + +P D + F T+ +M IMGF ++E +SI+RVVS+VL
Sbjct: 301 RNDLLLEGFNNYTFLSNGHVPIPAQQDDEMFQETLEAMTIMGFTEEEQTSILRVVSSVLQ 360
Query: 1087 LGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQE 1266
LGN+ F +E+ +DQA + D+ QKVCHL+G+ V + ++ L PRIKVGR+ V KAQ +E
Sbjct: 361 LGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKE 420
Query: 1267 QAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQIC 1446
QA+FA+EA+AKA +ERLF+W++TR+NK+LD+T RQGASF+GILDIAGFEIF+INSFEQ+C
Sbjct: 421 QADFAIEALAKAKFERLFRWILTRVNKALDKTKRQGASFLGILDIAGFEIFEINSFEQLC 480
Query: 1447 INYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALL 1617
INYTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP I+LIE+P GVLALL
Sbjct: 481 INYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPTNPPGVLALL 540
Query: 1618 DEECLFPKANDKSFVEKLQKTHNKHPKF-IVPDMRSKSHFAVVHYAGRVDYSADQWLMKN 1794
DEEC FPKA D SFVEKL + H KF ++ K+ F ++HYAG+V Y+A WL KN
Sbjct: 541 DEECWFPKATDTSFVEKLIQEQGNHAKFQKSKQLKDKTEFCILHYAGKVTYNASAWLTKN 600
Query: 1795 MDPLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQ 1962
MDPLN+NV L+ S+D FVA +WKD + G+ A+M E++ +++KGMFRTV Q
Sbjct: 601 MDPLNDNVTSLLNQSSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQ 660
Query: 1963 LHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGF 2142
L+KEQLTKLMTTLRNT+P+FVRCIIPNHEK++GK++++LVLEQLRCNGVLEGIRICRQGF
Sbjct: 661 LYKEQLTKLMTTLRNTNPNFVRCIIPNHEKRAGKLDAHLVLEQLRCNGVLEGIRICRQGF 720
Query: 2143 PNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVL 2322
PNR+ FQEFR RYEIL + IPK F+DGK++ MI AL++D NLYRIGQSK+FFRTGVL
Sbjct: 721 PNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVL 780
Query: 2323 AHLEEERDLKLTALIMNFQAQCRGFLSRRLY 2415
AHLEEERDLK+T +I+ FQAQCRG+L+R+ +
Sbjct: 781 AHLEEERDLKITDVIIAFQAQCRGYLARKAF 811
>gi|12657350|emb|CAC27776.1| myosin heavy chain [Notothenia coriiceps]
Length = 1929
Score = 1064 bits (2751), Expect = 0.0
Identities = 634/1930 (32%), Positives = 1062/1930 (54%), Gaps = 32/1930 (1%)
Frame = +1
Query: 52 ATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKF 231
A A + + C+V D E +L ++ ++ + V+++ T + + ++V NPPK+
Sbjct: 27 AQSAPFDAKSACYVSDVKELYLKATLIKKDGGKATVKILGTEEERVVKEEEVFPLNPPKY 86
Query: 232 DKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKG 411
DKIEDM+ +T++NEASVL+NLK+RY + +IYTYSGLFC +NPYK LP+Y + + ++G
Sbjct: 87 DKIEDMAMMTHVNEASVLYNLKERYAAWMIYTYSGLFCATVNPYKWLPVYDAECVSAYRG 146
Query: 412 KKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLA--HVAGAT 585
KKR E PPHIF+++D AY+ M +RE+QS+L TGESGAGKT NTK+VIQY A V+G
Sbjct: 147 KKRMEAPPHIFSVSDNAYQFMATDRENQSVLITGESGAGKTVNTKRVIQYFATISVSGPK 206
Query: 586 RNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRI 765
R+ S G LE Q++ ANP+LE++GN+KTV+NDNSSRFGKFIRI
Sbjct: 207 RDASK------------------GSLEDQIIAANPLLESYGNAKTVRNDNSSRFGKFIRI 248
Query: 766 NFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYR 945
+F+ +G ++ A+IE YLLEKSRV Q ++ER +HIFYQ++ G E E L + Y
Sbjct: 249 HFNTAGKLASADIETYLLEKSRVTFQLEEERGYHIFYQMMTG-HKPELLELALLTTNPYD 307
Query: 946 F-LVNRG-ITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKK 1119
F + + G I + ++DD E +T N++ I+GF ++E SI ++ AVL GN++F Q+++
Sbjct: 308 FPMCSMGKIVVASIDDKVELEATDNAIDILGFTNEEKMSIYKMTGAVLHHGNMKFKQKQR 367
Query: 1120 SDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAK 1299
+QA KV +LLGL ++ K PR+KVG E+V K Q Q +V A+AK
Sbjct: 368 EEQAEPDGTDDADKVAYLLGLNSADMLKGLCYPRVKVGNEYVTKGQTVPQVMNSVPALAK 427
Query: 1300 ASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQL 1479
+ YER+F W+V RIN LD T + +IG+LDIAGFEIFD N+ EQ+CIN+TNEKLQQ
Sbjct: 428 SIYERMFLWMVIRINNMLD-TKQARQFYIGVLDIAGFEIFDFNTLEQLCINFTNEKLQQF 486
Query: 1480 FNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSF 1659
FN+TMF+LEQEEY++EGI W+FIDFG+DL I+LIE+PMG+ ++L+EEC+FPKA+D SF
Sbjct: 487 FNHTMFVLEQEEYKKEGIIWEFIDFGMDLAACIELIERPMGIFSILEEECMFPKASDTSF 546
Query: 1660 VEKLQKTH-NKHPKFIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGL 1827
KL H K+ F P ++++HF++VHYAG VDY+ WL KN DPLN++V+ L
Sbjct: 547 KNKLYDQHLGKNKAFEKPKPSKGKAEAHFSLVHYAGIVDYNISGWLDKNKDPLNDSVIQL 606
Query: 1828 MQNSTDPFVAGIWKDAEFAGICAAEMNETA--FGMRSRKGMFRTVSQLHKEQLTKLMTTL 2001
S+ + G+ + E A G + + G +TVS +E L KLMT L
Sbjct: 607 YMKSS----------VKLLGLLYPPVVEEAGKKGGKKKGGSMQTVSSQFRENLGKLMTNL 656
Query: 2002 RNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRY 2181
R+T PHFVRC+IPN K G + + LV+ QLRCNGVLEGIRICR+GFP+R+ + +F+ RY
Sbjct: 657 RSTHPHFVRCLIPNESKTPGLMENFLVIHQLRCNGVLEGIRICRKGFPSRILYADFKQRY 716
Query: 2182 EILTPDVIPK-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLT 2358
++L P VIP+ F+D K++ K++ ++D+ + Y+ G +KVFF+ G+L LEE RD KL
Sbjct: 717 KVLNPSVIPEGQFMDNKKASEKLLGSVDVPHDEYKFGHTKVFFKAGLLGTLEEMRDEKLA 776
Query: 2359 ALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQV 2538
+L+ QA RG++ R+ + N +++ +++W W +++ K+KPLLQ
Sbjct: 777 SLVTLTQALARGYIMRKAFIKMIERREAIYTIQYNIRSFMNVKHWPWMKVYYKIKPLLQS 836
Query: 2539 TRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELD 2718
T+ E+ + K L +E E+K+ ++ E+ + Q+ E EN ++ +
Sbjct: 837 AETEKELANMKENYDKMKTDLATALAKKKELEEKMVSLLQEKNDLSLQIASEGENLSDAE 896
Query: 2719 D-----IRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXX 2883
+ I+G++Q +E + + +RL +RK + +
Sbjct: 897 ERCEGLIKGKIQ-----MEAKLKETSERLEDEEEINAELTAKKRKLEDECSELKKDIDDL 951
Query: 2884 XXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERA 3063
+K + ++ L E++
Sbjct: 952 ELTLAKVEKEKHATENKVKNLTEEMASQDESIAKLTKEKKALQESHQQTLDDLQAEEDKV 1011
Query: 3064 KHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELN 3243
KAK +LE Q+ +LE L +E++ + +LE+ KRKL +L+ +++ + + ++ +
Sbjct: 1012 NTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESVMDLENDKQQSD 1071
Query: 3244 NQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRR 3423
++ K+D E L++ ++E + +QK+++++Q I+EL E++E ER AR K E R
Sbjct: 1072 EKIKKKDFECSQLLSKIEDEQSLGAQLQKKIKELQARIEELEEEIEAERAARAKVEKQRA 1131
Query: 3424 EVVAQLEKVKGDVLDKVDEATMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKF 3600
++ +LE++ + L++ AT Q MS+K E E +R +E+ E + K
Sbjct: 1132 DLSRELEEI-SERLEEAGGATSAQIEMSKKREAEFQKLRRDLEESTLQHEATAAALRKKQ 1190
Query: 3601 SRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHL 3780
+ V +L +QI+ ++ + +LEK++++ E D++ + + ++ +++K + E L
Sbjct: 1191 ADSVADLGEQIDNLQRVKQKLEKEKSEYKMEIDDLSSNMENVAKAKGNLEKMCRTLEDQL 1250
Query: 3781 MEIQANLAESDEHKRTLID---QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXX 3951
E++ ++DE+ R + D Q R E +R EE+E + + R +
Sbjct: 1251 SELK---TKNDENVRQINDTSSQKARLLTENGEYSRQIEEKEALVSQLTRGKQASTQQIE 1307
Query: 3952 XXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARR 4131
+ K A + + + + L ++ EE + +A L++ + A + R
Sbjct: 1308 ELKRHIEEEVKAKNALAHGLQSARHDCDLLREQFEEEQEAKAELQRGMSKANSEVAQWRS 1367
Query: 4132 KAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELE 4302
K E Q+ EEL + + + LQ+ E+ E + + ++K+++ E+ED +++E
Sbjct: 1368 KYETDAIQRTEELEESKKKLAQRLQEAEEQIEAVNSKCASLEKTKQRLLSEVEDLMIDVE 1427
Query: 4303 NVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKE 4482
A + +K+Q+ F+ +AE + ++ + + +E R T + + N + +
Sbjct: 1428 RANALAANLDKKQRNFDKVLAEWKQKYEEGQAELEGAQKEARSLSTELFKMKNSYEEALD 1487
Query: 4483 HLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQI 4662
HLE R ++LQQE+ D + GK++HELEK+K+ LE E +++ +EE E L+
Sbjct: 1488 HLETMKRENKNLQQEISDLTEQIGETGKSIHELEKSKKQLETEKTEIQTALEEAEGTLEH 1547
Query: 4663 AEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVS 4842
E LR+++ +K E DR ++ KD E E+ +R + I +++ L++E R ++ A+
Sbjct: 1548 EESKILRVQLELNQIKGEVDRKLAEKDEEMEQIKRNSQRVIDSMQSTLDSEVRSRNDALR 1607
Query: 4843 HRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLRE 5022
+KK+E + E+E QL ANR E + Q+ ++A +A+ED
Sbjct: 1608 IKKKMEGDLNEMEIQLSHANRQASESQKQLRNVQAQLKDAQLHLDDALRAQEDFKEQAAM 1667
Query: 5023 ADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEE------KRRL 5184
+R+ + AE E+LR A E ++RK + G + S+ K++L
Sbjct: 1668 VERRNGLMMAEIEELRAALEQTERSRK---IAEQELVDASERVGLLHSQNTNLVNTKKKL 1724
Query: 5185 EAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSN 5364
E + Q A +K +KA + +L E+ + E K++LE +
Sbjct: 1725 ETDLVQIQGEVDDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEVAV 1784
Query: 5365 RDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDT 5544
+D + ++ E E+ A + Q+ LE++V+ LE ++ E + A + R+ E+R+ +
Sbjct: 1785 KDLQHRLDEAENLAMKGGKKQLQKLESRVRELEAEVEAEQRRGVDAVKGVRKYERRVKEL 1844
Query: 5545 TQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQ---READDLL 5715
T Q E++K+ + ++L++K LK + +RQ ++AE++ + +K R VQ EA++
Sbjct: 1845 TYQTEEDKKNVARLQDLVDKLQLKVKAYKRQSEDAEEQANTHLSKCRKVQHDMEEAEERA 1904
Query: 5716 DANEQLTREL 5745
D E +L
Sbjct: 1905 DIAESQVNKL 1914
>gi|21623523|dbj|BAC00871.1| myosin heavy chain [Oncorhynchus keta]
Length = 1937
Score = 1061 bits (2745), Expect = 0.0
Identities = 623/1899 (32%), Positives = 1044/1899 (54%), Gaps = 21/1899 (1%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRD----DVQKANPPKFDKIE 243
+ C+V D+ E +L G + + + V + + ++ D+ + NPPK+DKIE
Sbjct: 35 KNACYVTDKVELYLKGLVTARADGKCTVTVTNPDGSKEEGKEFEEADIYEMNPPKYDKIE 94
Query: 244 DMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRH 423
DM+ +TYLNEASVL+NLK+RY + +IYTYSGLFC +NPYK LP+Y E+++ ++GKKR
Sbjct: 95 DMAMMTYLNEASVLYNLKERYAAWMIYTYSGLFCATVNPYKWLPVYDEEVVNAYRGKKRM 154
Query: 424 EMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLN 603
E PPHIF+++D A++ M+ ++E+QSIL TGESGAGKT NTK VIQY A +A + K ++
Sbjct: 155 EAPPHIFSVSDNAFQFMMIDKENQSILITGESGAGKTVNTKCVIQYFATIAVSGSKKEVD 214
Query: 604 AAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSG 783
+ Q G LE Q++ ANP+LE++GN+KTV+NDNSSRFGKFIRI+F +G
Sbjct: 215 PSKMQ------------GSLEDQIIAANPLLESYGNAKTVRNDNSSRFGKFIRIHF-QAG 261
Query: 784 YISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRF-LVNR 960
++ A+IE YLLEKSRV Q DER +HIFYQ++ G E E L + Y F ++++
Sbjct: 262 KLAKADIETYLLEKSRVAFQLPDERGYHIFYQLMTG-HKPELVEMTLLTTNPYDFPMISQ 320
Query: 961 G-ITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAML 1137
G I +P+++D +E +T +++ I+GF +DE SI ++ AV GNL+F Q+++ +QA
Sbjct: 321 GHIAVPSINDKEELDATDDAITILGFTNDEKMSIYKLTGAVTHHGNLKFKQKQREEQAEP 380
Query: 1138 QDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERL 1317
V K+ +LLGL EL K PR+KVG E+V K Q Q AV A+AK+ YER+
Sbjct: 381 DGTEVADKIGYLLGLNSAELLKCLCYPRVKVGNEYVTKGQTVAQVYNAVMALAKSIYERM 440
Query: 1318 FKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMF 1497
F W+V RIN+ LD T +IG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+TMF
Sbjct: 441 FLWMVIRINEMLD-TKNPRQFYIGVLDIAGFEIFDYNSMEQLCINFTNEKLQQFFNHTMF 499
Query: 1498 ILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQK 1677
+LEQEEY++EGI W+FIDFG+DL I+LIEKP+G+ ++L+EEC+FPKA+D +F K
Sbjct: 500 VLEQEEYKKEGIVWEFIDFGMDLAACIELIEKPLGIFSILEEECMFPKASDTTFKNKFYD 559
Query: 1678 TH-NKHPKFIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTD 1845
H K F P + ++HF++VHYAG VDY+ WL KN DPLNE+V+ + ++
Sbjct: 560 QHLGKTKAFEKPKPAKGKPEAHFSLVHYAGTVDYNITGWLDKNKDPLNESVILMYGKASV 619
Query: 1846 PFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFV 2025
+A ++ A ++ G + + G +TVS +E L KLMT LR+T PHFV
Sbjct: 620 KLLATLYP-------AAPPEDKAKKGGKKKGGSMQTVSSQFRENLHKLMTNLRSTHPHFV 672
Query: 2026 RCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVI 2205
RC+IPN K G + + LV+ QLRCNGVLE +RICR+GFP+R+ + +F+ RY++L VI
Sbjct: 673 RCLIPNESKTPGLMENFLVIHQLRCNGVLEDLRICRKGFPSRIIYADFKQRYKVLNASVI 732
Query: 2206 PK-NFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQA 2382
P+ F+D K++ K++ ++D++ Y+ G +KVFF+ G+L LEE RD KL AL+ QA
Sbjct: 733 PEGQFMDNKKASEKLLGSIDVNHEDYKFGHTKVFFKAGLLGVLEEMRDEKLAALVGMVQA 792
Query: 2383 QCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIR 2562
RGFL RR ++ N +++ ++ W W +L+ K+KPLLQ T+ E+
Sbjct: 793 LSRGFLMRREFSKMMERRESIFSIQYNIRSFMNVKTWPWMKLYFKIKPLLQSAETEKELA 852
Query: 2563 AKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQT 2742
+ K L K + E+KL ++ ERA + Q+ E ++ + ++ L
Sbjct: 853 NMKENYEKMKTDLAKALATKKHLEEKLVALVQERADLALQVASEGQSLNDAEERCEGLIK 912
Query: 2743 RNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTN 2922
+LE + +M +RL +RK + + +K
Sbjct: 913 SKIQLEAKLKEMTERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHA 972
Query: 2923 VDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQ 3102
+ ++ L E++ KA+ +LE Q
Sbjct: 973 TENKVKNLTEEMASLDESVAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKARTKLEQQ 1032
Query: 3103 LHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQ 3282
+ +LE L +E++ + +LE+ KRKL +L+ +++ + + ++ + ++ K++ E
Sbjct: 1033 VDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDLENDKQQADEKIKKKEFETSQL 1092
Query: 3283 LTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDV 3462
L++ ++E + +QK+++++Q I+EL E++E ER AR K E R ++ +LE++ +
Sbjct: 1093 LSKVEDEQSLGAQLQKKIKELQARIEELEEEIEAERAARAKVERQRADLSRELEEI-SER 1151
Query: 3463 LDKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQ 3639
L++ AT Q D+ +++ E +R +E+ E + K + V EL +QI+
Sbjct: 1152 LEEAGGATSAQIDMNKKREAEFQKLRRDLEESTLQHEATAAALRKKQADSVAELGEQIDN 1211
Query: 3640 HKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEH 3819
++ + +LEK++++ E D++ + + ++ +++K + E L E++ E+
Sbjct: 1212 LQRVKQKLEKEKSEYKMEIDDLSSNMEAVAKAKGNLEKMCRTLEDQLSELKTKNDENVRQ 1271
Query: 3820 KRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIAN 3999
+ Q R E R EE+E + + R + K A
Sbjct: 1272 VNDISGQRARLLTENGEFGRQLEEKEALVSQLTRGKQAFTQQVEELKRQIEEEVKAKNAL 1331
Query: 4000 INRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESV---NQQLEEL 4170
+ + + + L ++ EE + +A L++ + A + R K E ++LEE
Sbjct: 1332 AHGVQSARHDCDLLREQFEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEA 1391
Query: 4171 RKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKF 4350
+KK + ++ ++ +E + + ++K+++Q E+ED +++E A + +K+Q+ F
Sbjct: 1392 KKKLAQRLQDAEETIEATNSKCSSLEKTKQRLQGEVEDLMIDVERANAMAANLDKKQRNF 1451
Query: 4351 ESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQEL 4530
+ +AE + ++ + + +E R T + L N + +HLE R ++LQQE+
Sbjct: 1452 DKVLAEWKQKYEEGQAELEGAQKEARSMSTELFKLKNSYEEALDHLETLKRENKNLQQEI 1511
Query: 4531 QDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALK 4710
D + GK++HELEKAK+++E E ++++ +EE E L+ E LR+++ +K
Sbjct: 1512 SDLTEQIGETGKSIHELEKAKKTVETEKSEIQTALEEAEGTLEHEESKILRVQLELNQIK 1571
Query: 4711 SESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
E DR I+ KD E E+ +R + + +++ L++E R ++ A+ +KK+E + E+E QL
Sbjct: 1572 GEVDRKIAEKDEEMEQIKRNSQRVVDSMQSTLDSEVRSRNDALRVKKKMEGDLNEMEIQL 1631
Query: 4891 EVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLR 5070
+NR E + Q+ ++A + ED+ +R+ + AE E+LR
Sbjct: 1632 SHSNRQASEAQKQLRNVQGQLKDAQLHLDDAVRVAEDMKEQAAMVERRNGLMVAEIEELR 1691
Query: 5071 EANEGLMQARKQXXXXXXXXXXXRAKGGGISSEE------KRRLEAKIAQXXXXXXXXQS 5232
A E + RK + G + S+ K++LE + Q
Sbjct: 1692 VALEQTERGRK---VAETELVDASERVGLLHSQNTSLLNTKKKLETDLVQVQGEVDDIIQ 1748
Query: 5233 NCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQS 5412
A +K +KA + +L E+ + E K++LE + +D + ++ E E+ A
Sbjct: 1749 EARNAEEKAKKAITDAAMMAEELKKEQDTSSHLERMKKNLEVTVKDLQHRLDEAENLAMK 1808
Query: 5413 RARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKE 5592
+ Q+ LE +V+ LE ++ E + A + R+ E+R+ + T Q E++K+ + ++
Sbjct: 1809 GGKKQLQKLEWRVRELETEVEAEQRRGVDAVKGVRKYERRVKELTYQTEEDKKNVGRLQD 1868
Query: 5593 LLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
L++K +K + +R +EAE+ ++ +K R VQ E ++
Sbjct: 1869 LVDKLQMKVKAYKRHAEEAEEAANQHMSKFRKVQHELEE 1907
Score = 135 bits (339), Expect = 2e-29
Identities = 161/882 (18%), Positives = 363/882 (40%), Gaps = 33/882 (3%)
Frame = +1
Query: 3166 KRKLLAELEDSKDH-LAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRD 3342
K LL LE+ +D LA +G V+ L+ + R E ++ E ++ +Q +R
Sbjct: 768 KAGLLGVLEEMRDEKLAALVGMVQALSRGFLMRRE-----FSKMMERRESIFSIQYNIRS 822
Query: 3343 MQTT-----------IDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATM 3489
I L + ETE+ N E EK+K D+ +
Sbjct: 823 FMNVKTWPWMKLYFKIKPLLQSAETEKELANMKE--------NYEKMKTDLAKALATKKH 874
Query: 3490 LQDLMSRKDEE-------VNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKK 3648
L++ + +E V + +++ + EG I+ K + +++E+ +++E ++
Sbjct: 875 LEEKLVALVQERADLALQVASEGQSLNDAEERCEGLIKS-KIQLEAKLKEMTERLEDEEE 933
Query: 3649 QRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRT 3828
++L ++ + + E +++ ++I L+ + A ++K++ E + + +A DE
Sbjct: 934 MNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMASLDESVAK 993
Query: 3829 LIDQLERSRDELDH-LNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANIN 4005
L + + ++ L+ ++ EE+ K+ +
Sbjct: 994 LTKEKKALQEAHQQTLDDLQAEED------------------------------KVNTLT 1023
Query: 4006 RAR-QLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAE-----ESVNQQLEE 4167
+AR +LE + + L E+ + LR LE+ A R+ G+ + E E+ QQ +E
Sbjct: 1024 KARTKLEQQVDDLEGSLEQEKKLRMDLER---AKRKLEGDLKLAQESIMDLENDKQQADE 1080
Query: 4168 LRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKK 4347
KK + L ++E+ + ++ + K++Q +E+ E+E RA+ E+++
Sbjct: 1081 KIKKKEFETSQLLSKVEDEQSLGAQLQKKIKELQARIEELEEEIEAERAARAKVERQRAD 1140
Query: 4348 FESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQE 4527
++ E +++A A + RE L +++ E + + +L+++
Sbjct: 1141 LSRELEEISERLEEAGGATSAQIDMNKKREAEFQKLRRDLE---ESTLQHEATAAALRKK 1197
Query: 4528 LQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQAL 4707
DS++ + G+ + L++ K+ LE E ++ ++++++L N++ A+ LE + L
Sbjct: 1198 QADSVA---ELGEQIDNLQRVKQKLEKEKSEYKMEIDDLSSNMEAVAKAKGNLEKMCRTL 1254
Query: 4708 KSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQ 4887
+ + E + K ++Q+ D+ + R ++ + GE +Q
Sbjct: 1255 EDQLS--------ELKTKNDENVRQVNDISGQ--------------RARLLTENGEFGRQ 1292
Query: 4888 LEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA----DRKFRAVEAE 5055
LE L + E + + EE +AK +A ++ A D E E
Sbjct: 1293 LEEKEALVSQLTRGKQAFTQQVEELKRQIEEEVKAKNALAHGVQSARHDCDLLREQFEEE 1352
Query: 5056 REQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSN 5235
+E E G+ +A + + E K++L ++ S
Sbjct: 1353 QEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEETIEATNSK 1412
Query: 5236 CELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES---GA 5406
C +++ Q ++E + D+ + + ++++ ++ ++K K E ++ GA
Sbjct: 1413 CSSLEKTKQRLQGEVEDLMIDVERANAMAANLDKKQRNFDKVLAEWKQKYEEGQAELEGA 1472
Query: 5407 QSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQA 5586
Q AR+ L E+ L+ R + L++ ++D T+Q + ++ +
Sbjct: 1473 QKEARSMSTELFKLKNSYEEALD----HLETLKRENKNLQQEISDLTEQIGETGKSIHEL 1528
Query: 5587 KELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
++ + + ++ L+EAE + E +K VQ E + +
Sbjct: 1529 EKAKKTVETEKSEIQTALEEAEGTLEHEESKILRVQLELNQI 1570
Score = 121 bits (303), Expect = 2e-25
Identities = 177/907 (19%), Positives = 367/907 (39%), Gaps = 127/907 (14%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ +E ++ +E+D ++ ++K+ + E + + +++ E A+L LQ
Sbjct: 1055 RKLEGDLKLAQESIMDLENDKQQADEKIKKKEFETSQLLSKVEDEQSLGAQLQKKIKELQ 1114
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + R +++E + + +
Sbjct: 1115 ARIEELEEEIEAER----AARAKVERQRADLSRELEEISERLEEAGGATSAQIDMNKKRE 1170
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K +
Sbjct: 1171 AEFQKLRRDLEESTLQHEATAAALRKKQADSVAELG---EQIDNLQRVKQKLEKEKSEYK 1227
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQ---LMKRDE 3267
++ +L ++ + K LE+ R L +L + K E + +V +++ Q L+ +
Sbjct: 1228 MEIDDLSSNMEAVAKAKGNLEKMCRTLEDQLSELKTKNDENVRQVNDISGQRARLLTENG 1287
Query: 3268 ELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEK 3447
E QL +E+ A V+ + + + ++EL+ +E E A+N + +
Sbjct: 1288 EFGRQL---EEKEALVSQLTRGKQAFTQQVEELKRQIEEEVKAKNALAHGVQSARHDCDL 1344
Query: 3448 VKGDVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEEL 3621
++ ++ + LQ MS+ + EV TK + IQ T E +EE K K ++++++
Sbjct: 1345 LREQFEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQDA 1402
Query: 3622 HDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEI---- 3789
+ IE + S LEK + + E D+ ++ A A++DKK++ + L E
Sbjct: 1403 EETIEATNSKCSSLEKTKQRLQGEVEDLMIDVERANAMAANLDKKQRNFDKVLAEWKQKY 1462
Query: 3790 ---QANLAESDEHKRTLIDQLERSRDE----LDHLNRVREEEEHAFANMQRRLATAXXXX 3948
QA L + + R++ +L + ++ LDHL ++ E + N+Q+ ++
Sbjct: 1463 EEGQAELEGAQKEARSMSTELFKLKNSYEEALDHLETLKRENK----NLQQEISDLTEQI 1518
Query: 3949 XXXXXXXXXXTRLKIANINRARQ-LEDEKNALLDEKEEAEGLRAHLEKEIHAAR----QG 4113
T I + +A++ +E EK+ + EEAEG H E +I + Q
Sbjct: 1519 GE--------TGKSIHELEKAKKTVETEKSEIQTALEEAEGTLEHEESKILRVQLELNQI 1570
Query: 4114 AGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSM 4293
GE RK E ++++E++++ + R V+ +Q L+ ++ L+ KKK++ +L + +
Sbjct: 1571 KGEVDRKIAEK-DEEMEQIKRNSQRVVDSMQSTLDSEVRSRNDALRVKKKMEGDLNEMEI 1629
Query: 4294 ELE--------------NVRASHRDS---------------------EKRQKKFESQMAE 4368
+L NV+ +D+ E+R +++ E
Sbjct: 1630 QLSHSNRQASEAQKQLRNVQGQLKDAQLHLDDAVRVAEDMKEQAAMVERRNGLMVAEIEE 1689
Query: 4369 ERVAVQKALLDRDAMSQELRDRETRV-------LSLLN-----EVDIMKEHLEESDRVR- 4509
RVA+++ R EL D RV SLLN E D+++ E D ++
Sbjct: 1690 LRVALEQTERGRKVAETELVDASERVGLLHSQNTSLLNTKKKLETDLVQVQGEVDDIIQE 1749
Query: 4510 -RSLQQELQDSISNKDDFGKNVHE-------LEKAKRSLEAELNDMRVQMEELED----- 4650
R+ +++ + +I++ + + + LE+ K++LE + D++ +++E E+
Sbjct: 1750 ARNAEEKAKKAITDAAMMAEELKKEQDTSSHLERMKKNLEVTVKDLQHRLDEAENLAMKG 1809
Query: 4651 -------------NLQIAEDARLRL----------------EVTNQALKSESD------- 4722
L+ +A R E+T Q + + +
Sbjct: 1810 GKKQLQKLEWRVRELETEVEAEQRRGVDAVKGVRKYERRVKELTYQTEEDKKNVGRLQDL 1869
Query: 4723 --------RAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGEL 4878
+A EAEE + + R +++ELE + A + K+ + +
Sbjct: 1870 VDKLQMKVKAYKRHAEEAEEAANQHMSKFRKVQHELEEAEERADIAETQVNKLRAKTRDS 1929
Query: 4879 EQQLEVA 4899
+ EVA
Sbjct: 1930 GKGKEVA 1936
Score = 90.1 bits (222), Expect = 6e-16
Identities = 93/466 (19%), Positives = 199/466 (41%), Gaps = 27/466 (5%)
Frame = +1
Query: 3037 QLLDHEERAKHGVKAKGR----LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKD 3204
+ LDH E K K + L Q+ E + ++ + K +E K ++ LE+++
Sbjct: 1492 EALDHLETLKRENKNLQQEISDLTEQIGETGKSIHELEKAKKTVETEKSEIQTALEEAEG 1551
Query: 3205 HLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMET 3384
L + K+ + +L + E+ ++ DEE M++ R+ Q +D ++ +++
Sbjct: 1552 TLEHEESKILRVQLELNQIKGEVDRKIAEKDEE------MEQIKRNSQRVVDSMQSTLDS 1605
Query: 3385 ERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHT 3564
E +RN A ++++ L +++ + +A+ Q + ++ + ++
Sbjct: 1606 EVRSRNDALRVKKKMEGDLNEMEIQLSHSNRQASEAQKQLRNVQGQLKDAQLHLDDAVRV 1665
Query: 3565 MEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRAD 3744
E ++EQ A R+ + +IE+ + Q E+ + A+ E D ++ + LL +
Sbjct: 1666 AED-MKEQAAMVERRNGLMVAEIEELRVALEQTERGRKVAETELVDASERVGLLHSQNTS 1724
Query: 3745 IDKKRKIHEAHLMEIQANLAESDEHKRT--------------LIDQLERSRDELDHLNRV 3882
+ +K E L+++Q + + + R + ++L++ +D HL R+
Sbjct: 1725 LLNTKKKLETDLVQVQGEVDDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSSHLERM 1784
Query: 3883 REEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEA 4062
++ E ++Q RL A ++ R+LE E A E+
Sbjct: 1785 KKNLEVTVKDLQHRLDEAENLAMKGGKKQLQKLEWRV------RELETEVEA-----EQR 1833
Query: 4063 EGLRAHLEKEIHAARQGAGEARRKAEESVNQ--QLEELRKKNLRDVEHLQKQLEESEVAK 4236
G+ A K + + E + EE +L++L K V+ ++ EE+E A
Sbjct: 1834 RGVDA--VKGVRKYERRVKELTYQTEEDKKNVGRLQDLVDKLQMKVKAYKRHAEEAEEAA 1891
Query: 4237 ERILQSKKKIQQELED-------SSMELENVRASHRDSEKRQKKFE 4353
+ + +K+Q ELE+ + ++ +RA RDS K ++ E
Sbjct: 1892 NQHMSKFRKVQHELEEAEERADIAETQVNKLRAKTRDSGKGKEVAE 1937
Score = 67.4 bits (163), Expect = 4e-09
Identities = 98/506 (19%), Positives = 204/506 (39%), Gaps = 19/506 (3%)
Frame = +1
Query: 4282 DSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLN 4461
++ EL N++ ++ EK + +A ++ +K + A+ QE D +V S
Sbjct: 846 ETEKELANMKENY---EKMKTDLAKALATKKHLEEKLV----ALVQERADLALQVASEGQ 898
Query: 4462 EVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE 4641
++ +E E + + L+ +L++ +D + EL KR LE E ++++ +++
Sbjct: 899 SLNDAEERCEGLIKSKIQLEAKLKEMTERLEDEEEMNAELTAKKRKLEDECSELKKDIDD 958
Query: 4642 LEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKR 4821
LE L E + E + L E ++ + ++++ L + + ++L+ E+
Sbjct: 959 LELTLAKVEKEKHATENKVKNLTEEM-ASLDESVAKLTKEKKALQEAHQQTLDDLQAEED 1017
Query: 4822 GKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKED 5001
+ R K+E Q+ +LE LE +L+ + + + + + A+++ D
Sbjct: 1018 KVNTLTKARTKLEQQVDDLEGSLEQEKKLRMDLERAKR-------KLEGDLKLAQESIMD 1070
Query: 5002 IAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRR 5181
+ ++AD K + E E QL E+++
Sbjct: 1071 LENDKQQADEKIKKKEFETSQLLS-----------------------------KVEDEQS 1101
Query: 5182 LEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERS 5361
L A++ + K ++ Q ++E++ ++ ER K E ++ L R
Sbjct: 1102 LGAQLQK-----------------KIKELQARIEELEEEIEAERAARAKVERQRADLSRE 1144
Query: 5362 NRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRA-ARRLEKRLN 5538
+ ++ E GA S EA+ Q L L +E T + A A L K+
Sbjct: 1145 LEEISERLEEA-GGATSAQIDMNKKREAEFQKLRRDL----EESTLQHEATAAALRKKQA 1199
Query: 5539 DTTQQFEDEKRANEQAKELLEK-------------SNLK-----NRNLRRQLDEAEDEMS 5664
D+ + ++ ++ K+ LEK SN++ NL + ED++S
Sbjct: 1200 DSVAELGEQIDNLQRVKQKLEKEKSEYKMEIDDLSSNMEAVAKAKGNLEKMCRTLEDQLS 1259
Query: 5665 RERTKHRNVQREADDLLDANEQLTRE 5742
+TK+ R+ +D+ +L E
Sbjct: 1260 ELKTKNDENVRQVNDISGQRARLLTE 1285
>gi|47213344|emb|CAF92967.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 1881
Score = 1061 bits (2743), Expect = 0.0
Identities = 630/1897 (33%), Positives = 1026/1897 (53%), Gaps = 22/1897 (1%)
Frame = +1
Query: 85 CWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTY 264
C+V D+ ++ G I+ V V D + V++ V NPPKFDKIEDM+ T+
Sbjct: 37 CFVVDEKVEYVKGQIQSRDGGMVTVRREDGAT-VSVPESGVHPQNPPKFDKIEDMAMFTF 95
Query: 265 LNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIF 444
L+E +VL NLK+RY + +IYTYSGLFCV +NPYK LP+Y +++ ++GKKR E PPHIF
Sbjct: 96 LHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYDAEVVAAYRGKKRSEAPPHIF 155
Query: 445 AIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNI 624
+I+D AY+ ML +RE+QS+L TGESGAGKT NTK+VIQY A +A + +A+
Sbjct: 156 SISDNAYQYMLSDRENQSVLITGESGAGKTVNTKRVIQYFASIAAVGGSSRKDASK---- 211
Query: 625 VQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANI 804
G LE Q++QANP LEAFGN+KTV+NDNSSRFGKFIRI+F SG +S A+I
Sbjct: 212 ----------GTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGPSGKLSSADI 261
Query: 805 EFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRFLVNRGITLPNVD 984
E YLLEK V +T+ +++
Sbjct: 262 ETYLLEK------------------------------------------VQGEVTVASIN 279
Query: 985 DVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQKV 1164
D +E +T ++ ++GF +E + ++ A++ GN++F Q ++ +QA K
Sbjct: 280 DSEELMATDSAFDVLGFTPEEKMGVYKLTGAIMHYGNMKFKQRQREEQAEPDGTEAADKS 339
Query: 1165 CHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRIN 1344
+L+GL +L K PR+KVG E+V K Q+ +Q +A+ A+AK+ YE++F W+V RIN
Sbjct: 340 AYLMGLNSSDLIKGLCHPRVKVGNEYVTKGQSVDQVYYALGALAKSVYEKMFNWMVVRIN 399
Query: 1345 KSLD-RTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
+SLD + HRQ FIG+LDIAGFEIFD N+FEQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 400 QSLDTKQHRQ--YFIGVLDIAGFEIFDFNTFEQLCINFTNEKLQQFFNHHMFVLEQEEYK 457
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGI+W+FIDFG+DLQ IDLIEKP+G+L++L+EEC+FPKA+D++F KL H K+
Sbjct: 458 KEGIDWEFIDFGMDLQACIDLIEKPLGILSILEEECMFPKASDQTFKSKLYDNHLGKNKM 517
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P R+++HFA+VHYAG VDY+ WL+KN DPLNE VVGL Q S+ ++ ++
Sbjct: 518 FEKPRAAKGRAEAHFALVHYAGTVDYNITNWLVKNKDPLNETVVGLYQKSSLKLLSLLFS 577
Query: 1870 DAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHE 2049
+ + G + + F+TVS LH+E L KLMT L+ T PHFVRC+IPN
Sbjct: 578 TYS----SDSSDKGGSKGAKKKGSSFQTVSALHRENLNKLMTNLKTTHPHFVRCLIPNER 633
Query: 2050 KKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDG 2226
K G +++ LV+ QLRCNGVLEGIRICR+GFPNRV + +F+ RY IL IP+ FID
Sbjct: 634 KSPGVMDNCLVMHQLRCNGVLEGIRICRKGFPNRVLYGDFKQRYRILNAAAIPEGQFIDC 693
Query: 2227 KESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSR 2406
K+S K++ +LDID Y+ G +KVFF+ G+L LEE RD +L+ ++ QA RG L R
Sbjct: 694 KKSAEKLLGSLDIDHTQYKFGHTKVFFKAGLLGTLEEMRDEQLSRILTRIQANARGILMR 753
Query: 2407 RLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRA 2586
+ N ++L ++NW W +LF K+KPLL+ + E+ + DE
Sbjct: 754 ARFAKMVEQRDALMVIQWNLRSFLGVKNWPWMKLFFKIKPLLKSAEAEKEMASMKDEFNK 813
Query: 2587 TKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYI 2766
KE L K E +E E+K+ ++ E+ + Q+Q E + + ++ +L LE
Sbjct: 814 LKEALEKSESRRKELEEKIVTLLQEKNNLTLQIQSEQDTLTDAEERCEQLIKSKIHLEAK 873
Query: 2767 VNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXX 2946
+ +M +RL RRK + + +K + +
Sbjct: 874 LKEMAERLEDEEEMNADLTAKRRKLEDECSELKKDIDDLELTLAKVEKEK-HATENKVKN 932
Query: 2947 XXXXXXXQDAYDXXXXXXXXXXXXXXGLT-TQLLDHEERAKHGVKAKGRLENQLHELEQD 3123
QDA T L E++A KAK +LE Q+ +LE
Sbjct: 933 LIEEMASQDATIAKLSKEKKALQEAHQQTLDDLQSEEDKANSLSKAKAKLEQQVDDLEGS 992
Query: 3124 LNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEE 3303
L +E++ + ++E+ KRKL +L+ ++ + + ++L +L K+D E +R ++E
Sbjct: 993 LEQEKKVRMDMERSKRKLEGDLKLLQESMMDLDNDKQQLEEKLKKKDFETVQLNSRLEDE 1052
Query: 3304 SANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEA 3483
A + +QK++++ Q ++EL E++E ER AR K E R ++ +LE + + L++ A
Sbjct: 1053 QAAASQLQKKLKESQARMEELEEELEAERAARAKVEKQRADLSRELEDI-SERLEEAGGA 1111
Query: 3484 TMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQ 3660
T Q +L ++D E +R +E++ E + K + V EL + I+ ++ + +
Sbjct: 1112 TSAQAELNKKRDAEFQKLRRELEELTLQHESTAAALRKKHADSVAELGEHIDNLQRVKQK 1171
Query: 3661 LEKQQNQADQERADMAQEIALLQASRADIDKKRKI-------HEAHLMEIQANLAESDEH 3819
LEK++ + E D+ + L ++++ +K + H+ E Q ++ E H
Sbjct: 1172 LEKEKRELKLELDDLCSNVETLVKAKSNAEKMCRAMEDGMNEHKHQQDEAQRSIGELSSH 1231
Query: 3820 KRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIAN 3999
+ L+ E L R EE+E + + R + + K A
Sbjct: 1232 RAKLL-------SESAELARRLEEKESLVSQLSRAKVSYKQQAEDLRRQLDEEAKAKSAL 1284
Query: 4000 INRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKK 4179
+ + + + L ++ EE + +A L++ + A R + E Q+ EEL +
Sbjct: 1285 AHAVQSARHDCDLLREQLEEEQEAKAELQRALSRANAEVSTWRSRYESDGIQRAEELEEA 1344
Query: 4180 NLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKF 4350
+ V+ LQ+ E E A + + ++K+++Q E+ED ++LE A+ +K+Q+ F
Sbjct: 1345 KKKLVQRLQEAEEAVEAANAKSSSLEKTKQRLQAEMEDLMVDLERSNAASAALDKKQRLF 1404
Query: 4351 ESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQEL 4530
+ +AE + +++ + +A +E R T + L N + EHLE R ++LQ+E+
Sbjct: 1405 DKTLAEWKQKFEESQCELEASQKEARSLSTELFKLKNAYEECLEHLETMKRENKNLQEEI 1464
Query: 4531 QDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALK 4710
+ + G++ HELEKA++ LE E +++ +EE E +L+ E L+ ++ +K
Sbjct: 1465 SELSEQLGEGGRSAHELEKARKQLEQERAELQAALEEAEGSLEHEESKILQSQLELNQVK 1524
Query: 4711 SESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
++ +R +S KD E E+ +R + + L+ LE+E R ++ A+ +KK+E+ + E+E QL
Sbjct: 1525 ADVERKLSEKDEEMEQAKRNYQRVLDSLQASLESETRSRNEALRVKKKMESDLNEMEIQL 1584
Query: 4891 EVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLR 5070
ANR E + Q + +EA A +D +R+ ++AE E++R
Sbjct: 1585 SQANRQAAEGQKQVRSLQASLKDLQTQLDEAHHANQDSRENAALLERRHNLLQAELEEVR 1644
Query: 5071 EANEGLMQARK----QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNC 5238
A E + ++RK + A+ + +++K+ EA + Q
Sbjct: 1645 AALEQMDRSRKLAEQELSEASERVQLLHAQNTSLINQKKKH-EADLLQLQAEAEEAVQEE 1703
Query: 5239 ELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRA 5418
A +K +KA + +L E+ E K+++E++ +D + ++ E E A
Sbjct: 1704 RNAEEKAKKAINDAAVMAEELKKEQDTCAHLERMKRNMEQTIKDLQQRLDEAEQVAMKGG 1763
Query: 5419 RAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELL 5598
+ Q+ LEA+++ LE +L E + T + + R+ E+R+ + Q +++++ + +EL+
Sbjct: 1764 KKQLHKLEARIKELEAELEAEQRRGTESTKGIRKYERRIKELAYQSQEDRKNLGRLQELV 1823
Query: 5599 EKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+K LK ++ +R +EAE+ + K R +Q + ++
Sbjct: 1824 DKLQLKVKSYKRAGEEAEEAAAANAAKLRKLQHQLEE 1860
Score = 107 bits (268), Expect = 3e-21
Identities = 160/797 (20%), Positives = 331/797 (41%), Gaps = 41/797 (5%)
Frame = +1
Query: 3478 EATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRS 3657
+A +L L +DE+++ R + +IQ G + +A+F++ VE+ + RS
Sbjct: 721 KAGLLGTLEEMRDEQLS---RILTRIQANARGIL--MRARFAKMVEQRDALMVIQWNLRS 775
Query: 3658 QLEKQQ----------------NQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEI 3789
L + +A++E A M E L+ + + +RK E+
Sbjct: 776 FLGVKNWPWMKLFFKIKPLLKSAEAEKEMASMKDEFNKLKEALEKSESRRK-------EL 828
Query: 3790 QANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXX 3969
+ + + K L Q++ +D L E+ + +++ +L
Sbjct: 829 EEKIVTLLQEKNNLTLQIQSEQDTLTDAEERCEQLIKSKIHLEAKLKEMAERLEDEEEMN 888
Query: 3970 XXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESV 4149
T + R+LEDE + L + ++ E A +EKE HA + + EE
Sbjct: 889 ADLTA-------KRRKLEDECSELKKDIDDLELTLAKVEKEKHATEN---KVKNLIEEMA 938
Query: 4150 NQQ--LEELRKKNLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRA 4314
+Q + +L K+ E Q+ L++ + +++ + ++K K++Q+++D LE +
Sbjct: 939 SQDATIAKLSKEKKALQEAHQQTLDDLQSEEDKANSLSKAKAKLEQQVDDLEGSLEQEKK 998
Query: 4315 SHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEE 4494
D E+ ++K E + +Q++++D D Q+L E ++ E + LE+
Sbjct: 999 VRMDMERSKRKLEGDLK----LLQESMMDLDNDKQQL---EEKLKKKDFETVQLNSRLED 1051
Query: 4495 SDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDA 4674
LQ++L++S + ++ + + A+ +E + D+ ++E++ + L+ A A
Sbjct: 1052 EQAAASQLQKKLKESQARMEELEEELEAERAARAKVEKQRADLSRELEDISERLEEAGGA 1111
Query: 4675 RLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKK 4854
S +A NK +AE ++ L +++ +L + E S A + RKK
Sbjct: 1112 T-------------SAQAELNKKRDAEFQK--LRRELEELTLQHE------STAAALRKK 1150
Query: 4855 IENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRK 5034
+ + EL + ++ R+K++ +E R+ K ++ L +
Sbjct: 1151 HADSVAELGEHIDNLQRVKQKLE-----------------KEKRELKLELDDLCSNVETL 1193
Query: 5035 FRAVEAEREQLREANEGLMQARKQXXXXXXXX---XXXRAKGGGISSEEKRRLEAK---I 5196
+A + R +G+ + + Q RAK S+E RRLE K +
Sbjct: 1194 VKAKSNAEKMCRAMEDGMNEHKHQQDEAQRSIGELSSHRAKLLSESAELARRLEEKESLV 1253
Query: 5197 AQXXXXXXXXQSNCE---LAIDKQRKAQVQL----EQITTDLSMERTLNQKTEAEKQSLE 5355
+Q + E +D++ KA+ L + D + R ++ + K L+
Sbjct: 1254 SQLSRAKVSYKQQAEDLRRQLDEEAKAKSALAHAVQSARHDCDLLREQLEEEQEAKAELQ 1313
Query: 5356 RSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRL 5535
R+ A+++ S +S + LE + L +L + AAN + LEK
Sbjct: 1314 RALSRANAEVSTWRSRYESDGIQRAEELEEAKKKLVQRLQEAEEAVEAANAKSSSLEKTK 1373
Query: 5536 NDTTQQFE----DEKRANEQAKELLEKSNLKNRNL---RRQLDEAEDEMSRERTKHRNVQ 5694
+ E D +R+N + L +K L ++ L +++ +E++ E+ + + R++
Sbjct: 1374 QRLQAEMEDLMVDLERSNAASAALDKKQRLFDKTLAEWKQKFEESQCELEASQKEARSLS 1433
Query: 5695 READDLLDANEQLTREL 5745
E L +A E+ L
Sbjct: 1434 TELFKLKNAYEECLEHL 1450
>gi|34859107|ref|XP_230774.2| similar to KIAA1512 protein [Rattus
norvegicus]
Length = 2195
Score = 1060 bits (2742), Expect = 0.0
Identities = 669/1966 (34%), Positives = 1044/1966 (53%), Gaps = 85/1966 (4%)
Frame = +1
Query: 67 WAQRKLCWVPDQNEGFLIGSIKRE-TNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIE 243
W +K WVPD+ + ++ +K E T V VE D + +T+ ++Q NPP+FD +E
Sbjct: 145 WDGKKRVWVPDEQDAYVEAEVKTEATGGRVTVETKD-QKVLTVRETEMQPMNPPRFDLLE 203
Query: 244 DMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRH 423
DM+ +T+LNEA+VLHNL+ RY +IYTYSGLFCV INPYK LP+Y+ ++ +KGK+R
Sbjct: 204 DMAMMTHLNEAAVLHNLRQRYARWMIYTYSGLFCVTINPYKWLPVYTATVVAAYKGKRRS 263
Query: 424 EMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLN 603
E PPHI+A+AD AY ML+ RE+QS+L TGESGAGKT NTK+VIQY A VA
Sbjct: 264 EAPPHIYAVADNAYNDMLRNRENQSMLITGESGAGKTVNTKRVIQYFAIVAALGDGPGKK 323
Query: 604 AAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSG 783
A Q + K G LE Q+++ANP +EAFGN+KT++NDNSSRF G
Sbjct: 324 A---QFLATKTG-----GTLEDQIIEANPAMEAFGNAKTLRNDNSSRFVS----GHTWEG 371
Query: 784 YISGANIEFY--LLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFL 951
A+ F LLEKSRV+ Q ER +H++YQIL G E + LL ++ +Y F
Sbjct: 372 RDKQASTPFSADLLEKSRVIFQLPGERGYHVYYQILSG-KKPELQDMLLLSMNPYDYHFC 430
Query: 952 VNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQA 1131
T+ N++D +E +T ++M I+GF+ DE + ++V A+L GN++F Q+++ +QA
Sbjct: 431 SQGVTTVDNMNDGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNMKFKQKQREEQA 490
Query: 1132 MLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYE 1311
K +L+G+ +L K L PR++VG E+V K Q+ EQ FAV A+AKA+Y+
Sbjct: 491 EADGTESADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQVVFAVGALAKATYD 550
Query: 1312 RLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDI-------------------NSF 1434
RLF+WLV+RIN++LD T FIG+LDIAGFEIF++ NSF
Sbjct: 551 RLFRWLVSRINQTLD-TKLPRQFFIGVLDIAGFEIFEVRRALNHGTVLSEAKADAWFNSF 609
Query: 1435 EQICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLAL 1614
EQ+CIN+TNEKLQQ FN MF+LEQEEY+REGI+W FIDFGLDLQP IDLIEKP+G+L++
Sbjct: 610 EQLCINFTNEKLQQFFNQHMFVLEQEEYKREGIDWVFIDFGLDLQPCIDLIEKPLGILSI 669
Query: 1615 LDEECLFPKANDKSFVEKLQKTHN-KHPKFIV--PDMRSK--SHFAVVHYAGRVDYSADQ 1779
L+EEC+FPKA+D SF KL H+ K P F PD + K +HF VVHYAG V YS
Sbjct: 670 LEEECMFPKASDASFRAKLYDNHSGKSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVG 729
Query: 1780 WLMKNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRK-GMFRTV 1956
WL KN DPLNE VV + Q S + +A ++++ +AG C+ E ++ + +K F+TV
Sbjct: 730 WLEKNKDPLNETVVPIFQKSQNRLLATLYEN--YAGSCSTEPPKSGVKEKRKKAASFQTV 787
Query: 1957 SQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQ 2136
SQLHKE L KLMT LR T PHFVRCI+PN K G ++S LVL QLRCNGVLEGIRICRQ
Sbjct: 788 SQLHKENLNKLMTNLRATQPHFVRCIVPNENKTPGVMDSFLVLHQLRCNGVLEGIRICRQ 847
Query: 2137 GFPNRVPFQEFRHRYEILTPDVIPKN-FIDGKESVRKMITALDIDTNLYRIGQSKVFFRT 2313
GFPNR+ + +FR RY IL P IP + F+D +++ K++ +LDID Y+ G +KVFF+
Sbjct: 848 GFPNRLLYADFRQRYRILNPSAIPDDTFVDSRKATEKLLGSLDIDHTQYQFGHTKVFFKA 907
Query: 2314 GVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNW 2493
G+L LEE RD +L ++ QA+ RG L R Y N A+ ++NW
Sbjct: 908 GLLGILEELRDQRLAKVLTLLQARSRGRLMRLEYQRMLGGRDALFTIQWNIRAFNAVKNW 967
Query: 2494 QWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVI 2673
W +LF K+KPLL+ + ++E+ A ELR + L E +E E+ V E+ +
Sbjct: 968 SWMKLFFKMKPLLRSAQAEEELAALRAELRGLRGALATAEAKRQELEETQVSVTQEKNDL 1027
Query: 2674 QEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETV 2853
QLQ E +N A+ ++ L +LE V ++ +RL RRK +
Sbjct: 1028 ALQLQAEQDNLADAEERCHLLIKSKVQLEAKVKELNERLEDEEEVNADLAARRRKLEDEC 1087
Query: 2854 RDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLT 3033
+ +K + ++
Sbjct: 1088 TELKKDIDDLELTLAKAEKEKQATENKVKNLTEEMAALDESVVRLTKEKKALQEAHQQAL 1147
Query: 3034 TQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLA 3213
L E+R KAK RLE Q+ +LE L +E++ + + E+ KRKL +L+ +++ +
Sbjct: 1148 GDLQAEEDRVSALAKAKIRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQETVT 1207
Query: 3214 EKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDM---------------- 3345
+ ++L +L K+D EL R ++E +QK+++++
Sbjct: 1208 DTTQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQLQKKIKELQVCTAAVGTAMGGPGL 1267
Query: 3346 -----------QTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATML 3492
Q +EL E++E ER AR + E R E +LE++ + + +
Sbjct: 1268 LQGLTDSVPFTQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQ 1327
Query: 3493 QDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQ 3672
++ +++ E+ +R +E+ E + + K + EL +Q++ ++ R +LEK+
Sbjct: 1328 REGCRKREAELGRLRRELEETVLRHEATVAALRRKQADSAAELSEQVDSLQRIRQKLEKE 1387
Query: 3673 QNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERS 3852
+++ E D+ + L +A +K + +E L E + + E Q R
Sbjct: 1388 KSELRMEVDDLGASVETLARGKASAEKLCRTYEDQLSEAKIKVEELQRQLTDASTQRGRL 1447
Query: 3853 RDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEK 4032
+ E L R+ EE+E + + R +A + K+ + L +
Sbjct: 1448 QTENGELGRLLEEKESMISQLSRGKTSAAQSLEELRRQLEEES--KVDGTGDVQALRHDC 1505
Query: 4033 NALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQ 4212
+ L ++ EE +A L++ + A + R K E Q+ EEL + + LQ+
Sbjct: 1506 DLLREQHEEESEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEA 1565
Query: 4213 LEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAV 4383
E E A + + ++K ++Q E ED ++ELE ++ +K+Q+ E + E R
Sbjct: 1566 EEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQE 1625
Query: 4384 QKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFG 4563
++ + +A +E R T + L + + E LE R ++LQ+E+ D G
Sbjct: 1626 EEMQRELEAAQREARGLGTELFRLRHSHEEALEALETLKRENKNLQEEISDLTDQVSLSG 1685
Query: 4564 KNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
K++ ELEKAK++LE E ++++ +EE E L++ E LR+++ +K+E DR ++ KD
Sbjct: 1686 KSIQELEKAKKALEGEKSELQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKD 1745
Query: 4744 VEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYX 4923
E RR + + L+ L+ E R ++ A+ +KK+E + +LE QL A R E
Sbjct: 1746 EECTNLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQAME-- 1803
Query: 4924 XXXXXXXXXXXEYQIECEEA-RQAKEDIAALLRE----ADRKFRAVEAEREQLREANEGL 5088
+ Q++ E+A R ++ +AA LRE +R+ + +E E+LR A E
Sbjct: 1804 ---AQAATRLLQAQLKEEQAGRDEEQRLAAELREQGQALERRAALLASELEELRAALEQG 1860
Query: 5089 MQARK----QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDK 5256
++R+ + ++ G+ + +K++LE +AQ A +K
Sbjct: 1861 ERSRRLAEQELLEATERLNLLHSQNTGLLN-QKKKLEVDLAQLSGEVEEAAQERREAEEK 1919
Query: 5257 QRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAA 5436
+KA + +L E+ + E K++LE++ R+ +A++ E E A + Q+
Sbjct: 1920 AKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQK 1979
Query: 5437 LEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLK 5616
LEAKV+ LE +L+ E ++ A + R+ E+R+ + Q E++++ + ++L++K K
Sbjct: 1980 LEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQTEEDRKNLARMQDLVDKLQSK 2039
Query: 5617 NRNLRRQLDEA---------------EDEMSRERTKHRNVQREADD 5709
++ +RQ +EA E + S K+R Q E DD
Sbjct: 2040 VKSYKRQFEEAVSTLGSRYLGLLSTVEQQASTNLAKYRKAQHELDD 2085
Score = 103 bits (257), Expect = 5e-20
Identities = 154/756 (20%), Positives = 302/756 (39%), Gaps = 32/756 (4%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKR 3759
EE+ A ++ L + + +R +LE+ Q QE+ D+A + LQA
Sbjct: 986 EEELAALRAELRGLRGALATAEAKRQELEETQVSVTQEKNDLALQ---LQAE-------- 1034
Query: 3760 KIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAX 3939
Q NLA+++E LI + ++ LN E+EE A++ R
Sbjct: 1035 ----------QDNLADAEERCHLLIKSKVQLEAKVKELNERLEDEEEVNADLAAR----- 1079
Query: 3940 XXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAAR---Q 4110
R+LEDE L + ++ E A EKE A +
Sbjct: 1080 -----------------------RRKLEDECTELKKDIDDLELTLAKAEKEKQATENKVK 1116
Query: 4111 GAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERI---LQSKKKIQQELE 4281
E +ESV + +E KK L++ Q+ L + + ++R+ ++K +++Q++E
Sbjct: 1117 NLTEEMAALDESVVRLTKE--KKALQEAH--QQALGDLQAEEDRVSALAKAKIRLEQQVE 1172
Query: 4282 DSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLN 4461
D LE + D+E+ ++K E + + V D+ + ++L+ +++
Sbjct: 1173 DLECSLEQEKKLRMDTERAKRKLEGDLKLTQETVTDTTQDKQQLEEKLKKKDS------- 1225
Query: 4462 EVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE 4641
E+ + +E+ + LQ+++++ G + + L + + + EE
Sbjct: 1226 ELSQLSLRVEDEQLLGAQLQKKIKELQVCTAAVGTAMGG-PGLLQGLTDSVPFTQARAEE 1284
Query: 4642 LEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENEL----- 4806
LE+ L+ AR R+E E + +S + EA G + R E EL
Sbjct: 1285 LEEELEAERAARARVEKQRAEAARELEE-LSERLEEAGGASAGQREGCRKREAELGRLRR 1343
Query: 4807 ---ENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECE 4977
E R ++ + R+K + EL +Q++ R++++ E ++E +
Sbjct: 1344 ELEETVLRHEATVAALRRKQADSAAELSEQVDSLQRIRQKLEKEKS-------ELRMEVD 1396
Query: 4978 EARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGG 5157
+ + E +A A++ R E +QL EA + + ++Q + + G
Sbjct: 1397 DLGASVETLARGKASAEKLCRTYE---DQLSEAKIKVEELQRQLTDASTQRGRLQTENGE 1453
Query: 5158 ISS--EEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQV--QLEQITTDLSMERTLNQ 5325
+ EEK + +++++ ++++ K ++ + D + R ++
Sbjct: 1454 LGRLLEEKESMISQLSRGKTSAAQSLEELRRQLEEESKVDGTGDVQALRHDCDLLREQHE 1513
Query: 5326 KTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAAN 5505
+ + L+R A++ + S ++ A + LE + L +L + AAN
Sbjct: 1514 EESEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAAN 1573
Query: 5506 RAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDE---AEDEMSRE-- 5670
LEK + ED E+A + K R+L R L+E E+EM RE
Sbjct: 1574 AKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELE 1633
Query: 5671 ---------RTKHRNVQREADDLLDANEQLTRELMN 5751
T+ ++ ++ L+A E L RE N
Sbjct: 1634 AAQREARGLGTELFRLRHSHEEALEALETLKRENKN 1669
>gi|26342663|dbj|BAC34988.1| unnamed protein product [Mus musculus]
Length = 778
Score = 1056 bits (2732), Expect = 0.0
Identities = 522/781 (66%), Positives = 631/781 (79%), Gaps = 8/781 (1%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL V RA + +PAT A W +KL W+P + GF SIK E DEV+VEL + ++ +
Sbjct: 12 RYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMV 71
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDM+ELT LNEASVLHNLKDRYYS LIYTYSGLFCVVINPYK L
Sbjct: 72 NKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNL 131
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYSE++IE ++GKKRHEMPPHI+AI+++AYR MLQ+REDQSILCTGESGAGKTENTKKV
Sbjct: 132 PIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKV 191
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
IQYLAHVA + + + + N GELE QLLQANPILE+FGN+KTVKND
Sbjct: 192 IQYLAHVASSHKGRKDH--------------NIPGELERQLLQANPILESFGNAKTVKND 237
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFYQ+L G KS
Sbjct: 238 NSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKS 297
Query: 913 EYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 1092
+ LLEG +NYRFL N I +P D F T+ +M IMGF+ +EI S+++VVS+VL G
Sbjct: 298 DLLLEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFG 357
Query: 1093 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA 1272
N+ F +E+ +DQA + ++ V QK+CHLLG+ V+E +A L PRIKVGR++V KAQ +EQA
Sbjct: 358 NISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQA 417
Query: 1273 EFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICIN 1452
+FAVEA+AKA+YERLF+WLV RINK+LDRT RQGASFIGILDIAGFEIF++NSFEQ+CIN
Sbjct: 418 DFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCIN 477
Query: 1453 YTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDE 1623
YTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP IDLIE+P GVLALLDE
Sbjct: 478 YTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDE 537
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMD 1800
EC FPKA DK+FVEKL + H KF P ++ K+ F ++HYAG+VDY AD+WLMKNMD
Sbjct: 538 ECWFPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMD 597
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAFG--MRSRKGMFRTVSQLH 1968
PLN+NV L+ S+D FVA +WKD + G+ M ETAFG +++KGMFRTV QL+
Sbjct: 598 PLNDNVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLY 657
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
KE LTKLM TLRNT+P+FVRCIIPNHEK++GK++ +LVL+QLRCNGVLEGIRICRQGFPN
Sbjct: 658 KESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPN 717
Query: 2149 RVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAH 2328
R+ FQEFR RYEILTP+ IPK F+DGK++ +MI AL++D NLYRIGQSK+FFR GVLAH
Sbjct: 718 RIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAH 777
Query: 2329 L 2331
L
Sbjct: 778 L 778
>gi|50757613|ref|XP_415578.1| PREDICTED: similar to myosin heavy chain
[Gallus gallus]
Length = 3503
Score = 1047 bits (2708), Expect = 0.0
Identities = 622/1891 (32%), Positives = 1034/1891 (53%), Gaps = 17/1891 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V E ++ +I+ + + +V V+ + +T+ D + NPPK+DKIEDM+ +T+L
Sbjct: 39 FVVHAKESYVKSTIQSKESGKVTVK-TEGGETLTVKEDQIFSMNPPKYDKIEDMAMMTHL 97
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 98 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVLAYRGKKRQEAPPHIFS 157
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A + K
Sbjct: 158 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAASGDKKK---------- 207
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
++ G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 208 EEQPAGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIE 267
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPNV 981
YLLEKSRV Q + ERS+HIFYQI+ E E LL + +Y+++ IT+P++
Sbjct: 268 TYLLEKSRVTFQLKAERSYHIFYQIMSN-KKPELIEMLLITTNPYDYQYVSQGEITVPSI 326
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
+D +E +T +++ I+GF DE ++I ++ AV+ GNL+F Q+++ +QA V K
Sbjct: 327 NDQEELMATDSAIDILGFTPDEKTAIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADK 386
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L+GL +L KA PR+KVG E+V K Q +Q +V A+AK+ +E++F W+V RI
Sbjct: 387 AAYLMGLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNSVGALAKSVFEKMFLWMVVRI 446
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 447 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H K
Sbjct: 506 KEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNN 565
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P ++++HF++VHYAG VDY+ WL KN DPLNE VVGL Q S+ +A +
Sbjct: 566 FQKPKPGKGKAEAHFSLVHYAGTVDYNITGWLEKNKDPLNETVVGLYQKSSLKTLALL-- 623
Query: 1870 DAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHE 2049
FA + AE
Sbjct: 624 ---FASVGGAE------------------------------------------------- 631
Query: 2050 KKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDG 2226
+G + LVL QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L IP+ FID
Sbjct: 632 --AGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDS 689
Query: 2227 KESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSR 2406
K++ K++ ++D+D Y+ G +KVFF+ G+L LEE RD KL LI QA+CRGFL R
Sbjct: 690 KKASEKLLGSIDVDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQARCRGFLMR 749
Query: 2407 RLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRA 2586
+ N A++ +++W W +LF K+KPLL+ ++ E+ +E
Sbjct: 750 VEFKKMMERRESIFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAESEKEMANMKEEFEK 809
Query: 2587 TKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYI 2766
TKE L K E +E E+K+ ++ E+ +Q Q+Q E++ A+ ++ +L +LE
Sbjct: 810 TKEELAKSEAKRKELEEKMVSLLQEKNDLQLQVQAEADGLADAEERCDQLIKTKIQLEAK 869
Query: 2767 VNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXX 2946
+ ++ +R +RK + + +K +
Sbjct: 870 IKELTERAEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 929
Query: 2947 XXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDL 3126
+ L E++ KAK +LE Q+ +LE L
Sbjct: 930 TEEMAALDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSL 989
Query: 3127 NRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEES 3306
+E++ + +LE+ KRKL +L+ +++ + ++L+ +L K+D E+ ++ ++E
Sbjct: 990 EQEKKLRMDLERAKRKLEGDLKMTQESTMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQ 1049
Query: 3307 ANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT 3486
A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L++ AT
Sbjct: 1050 ALGMQLQKKIKELQARIEELEEEIEAERTSRAKAEKHRADLSRELEEI-SERLEEAGGAT 1108
Query: 3487 MLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQL 3663
Q D+ +++ E +R +E+ E + K + EL +QI+ ++ + +L
Sbjct: 1109 AAQIDMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKL 1168
Query: 3664 EKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLID-- 3837
EK++++ E D+A + + ++A+++K + E L EI+ + +E +RT+ D
Sbjct: 1169 EKEKSELKMEIDDLASNMESVSKAKANLEKMCRSLEDQLSEIK---TKEEEQQRTINDIS 1225
Query: 3838 -QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRAR 4014
Q R + E +R EE++ + + R + K A + +
Sbjct: 1226 AQKARLQTESGEYSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKNALAHALQ 1285
Query: 4015 QLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDV 4194
+ + L ++ EE + + L++ + A + R K E Q+ EEL + +
Sbjct: 1286 SARHDCDLLREQYEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA 1345
Query: 4195 EHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMA 4365
+ LQ E E + + ++K+++Q E+ED +++E A+ +K+QK F+ ++
Sbjct: 1346 QRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACAALDKKQKNFDKILS 1405
Query: 4366 EERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSIS 4545
E + ++ + +A +E R T + + N + +HLE R ++LQQE+ D
Sbjct: 1406 EWKQKYEETQAELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEISDLTE 1465
Query: 4546 NKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDR 4725
+ GK +HELEK K+ +E E ++++ +EE E +L+ E LR+++ +KS+ DR
Sbjct: 1466 QIAEGGKAIHELEKVKKQIEQEKSELQAALEEAEASLEHEEGKILRVQLELNQVKSDIDR 1525
Query: 4726 AISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANR 4905
I+ KD E ++ +R L+ + +++ L+ E R ++ A+ +KK+E + E+E QL ANR
Sbjct: 1526 KIAEKDEEIDQLKRNHLRVVDSMQSTLDAEIRSRNEALRLKKKMEGDLNEIEIQLSHANR 1585
Query: 4906 LKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEG 5085
E + QI ++A +++ED+ + +R+ ++AE E+LR A E
Sbjct: 1586 QAAEAQKNLRNTQGVLKDTQIHLDDALRSQEDLKEQVAMVERRANLLQAEIEELRAALEQ 1645
Query: 5086 LMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDK 5256
++RK Q K++LE+ I+Q A +K
Sbjct: 1646 TERSRKVAEQELLDASERVQLLHTQNTSLINTKKKLESDISQIQSEMEDTIQEARNAEEK 1705
Query: 5257 QRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAA 5436
+KA + +L E+ + E K++L+++ +D + ++ E E A + Q+
Sbjct: 1706 AKKAITDAAMMAEELKKEQDTSAHLERMKKNLDQTVKDLQHRLDEAEQLALKGGKKQIQK 1765
Query: 5437 LEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLK 5616
LEA+V+ LE +++ E + A + R+ E+R+ + T Q E++++ + ++L++K +K
Sbjct: 1766 LEARVRELEGEVDAEQKRSAEAVKGVRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQMK 1825
Query: 5617 NRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
++ +RQ +EAE+ + +K R +Q E ++
Sbjct: 1826 VKSYKRQAEEAEELSNVNLSKFRKIQHELEE 1856
Score = 291 bits (745), Expect = 1e-76
Identities = 155/310 (50%), Positives = 215/310 (69%), Gaps = 2/310 (0%)
Frame = +1
Query: 85 CWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTY 264
C+V DQ + ++ G+I+ +V V+ D + VT+ D+V NPPK+DKIEDM+ +T+
Sbjct: 2076 CFVVDQKQMYVKGTIQSREGGKVTVKTYDDTT-VTVKDDEVFPMNPPKYDKIEDMAMMTH 2134
Query: 265 LNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIF 444
L+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF
Sbjct: 2135 LHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVSGYRGKKRQEAPPHIF 2194
Query: 445 AIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNI 624
+I+D AY+ ML +R++QSIL TGESGAGKT NTK+VIQY A +A K ++
Sbjct: 2195 SISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKDQQPSKMQ- 2253
Query: 625 VQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANI 804
G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+I
Sbjct: 2254 ----------GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADI 2303
Query: 805 EFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRF-LVNRG-ITLPN 978
E YLLEKSRV Q ERS+HIFYQI+ E + LL + Y F V++G IT+ +
Sbjct: 2304 ETYLLEKSRVTFQLASERSYHIFYQIMSN-KKPELIDLLLISTNPYDFAYVSQGEITVAS 2362
Query: 979 VDDVQEFHST 1008
+DD +E +T
Sbjct: 2363 IDDSEELLAT 2372
Score = 276 bits (705), Expect = 6e-72
Identities = 137/265 (51%), Positives = 187/265 (69%), Gaps = 4/265 (1%)
Frame = +1
Query: 1012 NSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVI 1191
N++ I+GF+ DE + ++ AV+ GN++F Q+++ +QA V K +L+GL
Sbjct: 2433 NAVDILGFSPDEKVGMYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLMGLNSA 2492
Query: 1192 ELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQ 1371
EL KA PR+KVG E+V K QN +Q +V A+AK+ YE++F W+VTRIN+ LD T +
Sbjct: 2493 ELLKALCYPRVKVGNEYVTKGQNVQQVYNSVGALAKSVYEKMFLWMVTRINQQLD-TKQP 2551
Query: 1372 GASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFID 1551
FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY++EGI+W+FID
Sbjct: 2552 RQHFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIDWEFID 2611
Query: 1552 FGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPKFIVPDM---R 1719
FG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H K F P +
Sbjct: 2612 FGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGK 2671
Query: 1720 SKSHFAVVHYAGRVDYSADQWLMKN 1794
+++HF++VHYAG VDY+ WL KN
Sbjct: 2672 AEAHFSLVHYAGTVDYNISGWLEKN 2696
Score = 179 bits (455), Expect = 6e-43
Identities = 119/455 (26%), Positives = 221/455 (48%), Gaps = 3/455 (0%)
Frame = +1
Query: 4354 SQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQ 4533
S MAE R Q++ + +A +E R T + + N + + + +E R ++LQQE+
Sbjct: 2761 SVMAEWRQKYQESQAELEAAQKESRTLSTEIFQMKNAYEEVLDQVETVRRENKNLQQEIS 2820
Query: 4534 DSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKS 4713
D + GK H LEKAK+ E E D++ +EE E +L+ E LR+++ +KS
Sbjct: 2821 DLTEQLAEAGKASHGLEKAKKQTEQEKYDLQAALEEAEGSLEHEEGKILRVQLELNQVKS 2880
Query: 4714 ESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLE 4893
+ DR + KD E ++ ++ + + ++ L+ E R ++ A+ +KK+E + ++E QL
Sbjct: 2881 DVDRRSAEKDEEIQQLKKNHQRVLESMQTTLDAEIRSRNDALRLKKKMEGDLNDMEIQLS 2940
Query: 4894 VANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLRE 5073
AN E + Q+ ++A + +D+ L +R+ + E EQ+R
Sbjct: 2941 RANCQVAETQKHLKVVQGQLKDSQLHLDDALRENDDLKEQLAVIERRNNLMMTELEQMRA 3000
Query: 5074 ANEGLMQARK---QXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCEL 5244
A E +ARK Q K++LE I
Sbjct: 3001 ALEQTERARKVSEQELTDASERVQILHSQNTSLLNTKKKLEVDITHLQNEVEDSIQEARN 3060
Query: 5245 AIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARA 5424
A +K +KA + +L E+ + E K++LE+ +D + ++ E E A +
Sbjct: 3061 AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKRNLEQMVKDLQHRLDEAEQLALKGGKK 3120
Query: 5425 QMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEK 5604
Q+ LEA++ LE++L++E + T + + AR+ E+RL + T Q E++K+ + + L++K
Sbjct: 3121 QLQKLEARIHELENELDIEQKRGTESLKGARKYERRLKELTYQSEEDKKNILRLQNLVDK 3180
Query: 5605 SNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
LK + ++Q +EAE++ S ++ R Q E ++
Sbjct: 3181 LQLKVKAYKKQAEEAEEQASTNLSRCRKTQHELEE 3215
Score = 166 bits (419), Expect = 8e-39
Identities = 189/943 (20%), Positives = 398/943 (42%), Gaps = 57/943 (6%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + + +++L + + ELE+ LL E D + + A+ + EE +
Sbjct: 798 KEMANMKEEFEKTKEELAKSEAKRKELEEKMVSLLQEKNDLQLQVQAEADGLADAEERCD 857
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE N L K+ R ++ EL++D++ E
Sbjct: 858 QLIKTKIQLEAKIKELTERAEDEEEMNAELTAKK-RKLEDECSELKKDIDD-------LE 909
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E L + +++ +E A + A +Q ++ +
Sbjct: 910 LTLAKVEKEKHATENKVKNLTEEMAALDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 969
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIAL-LQASRADID 3750
+ + K K +QV++L +EQ KK R LE+ + + + + M QE + L+ + +D
Sbjct: 970 TLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGD-LKMTQESTMDLENDKQQLD 1028
Query: 3751 KKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLA 3930
+K K + + +IQ+ + E ++ L QL++ EL R+ E EE A R
Sbjct: 1029 EKLKKKDFEISQIQSKI----EDEQALGMQLQKKIKELQ--ARIEELEEEIEAERTSRAK 1082
Query: 3931 TAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQ 4110
RL+ A A Q++ +++K EAE
Sbjct: 1083 AEKHRADLSRELEEISERLEEAGGATAAQID------MNKKREAE--------------- 1121
Query: 4111 GAGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELE 4281
+ RR EE+ Q LRKK+ L +Q++ + K+++ + K +++ E++
Sbjct: 1122 -FQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEID 1180
Query: 4282 DSSMELENVRASHRDSEKRQKKFESQMAEER------------VAVQKALLDRDA--MSQ 4419
D + +E+V + + EK + E Q++E + ++ QKA L ++ S+
Sbjct: 1181 DLASNMESVSKAKANLEKMCRSLEDQLSEIKTKEEEQQRTINDISAQKARLQTESGEYSR 1240
Query: 4420 ELRDRETRVLSL-------LNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHE 4578
++ +++ + L +++ +K HLEE + + +L LQ + + D + E
Sbjct: 1241 QVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKNALAHALQSARHDCDLLREQYEE 1300
Query: 4579 LEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDR---------AI 4731
++AK L+ L+ + E + + DA R E +A K + R A+
Sbjct: 1301 EQEAKGELQRALS--KANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAV 1358
Query: 4732 SNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLK 4911
++K E+ ++ L ++ DL ++E + +K + + E +Q+ E
Sbjct: 1359 NSKCASLEKTKQRLQNEVEDLMIDVERSNAACAALDKKQKNFDKILSEWKQKYE------ 1412
Query: 4912 EEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLM 5091
E Q E E +++ ++ L + + E L+ N+ L
Sbjct: 1413 ---------------ETQAELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQ 1457
Query: 5092 QARKQXXXXXXXXXXXRAKGGGISSE---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQR 5262
Q A+GG E K+++E + ++ +++ E K
Sbjct: 1458 QEISDLTEQI-------AEGGKAIHELEKVKKQIEQEKSELQAALEEAEASLEHEEGKIL 1510
Query: 5263 KAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAAL- 5439
+ Q++L Q+ +D +++K + + +++ R++ + ++S + R++ AL
Sbjct: 1511 RVQLELNQVKSD------IDRKIAEKDEEIDQLKRNHLRVVDSMQSTLDAEIRSRNEALR 1564
Query: 5440 -----EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEK 5604
E + +E QL+ ++ A + R + L DT +D R+ E KE +
Sbjct: 1565 LKKKMEGDLNEIEIQLSHANRQAAEAQKNLRNTQGVLKDTQIHLDDALRSQEDLKEQVAM 1624
Query: 5605 SNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQL 5733
+ L+ +++E + + + ++E LLDA+E++
Sbjct: 1625 VERRANLLQAEIEELRAALEQTERSRKVAEQE---LLDASERV 1664
Score = 139 bits (349), Expect = 1e-30
Identities = 173/891 (19%), Positives = 366/891 (40%), Gaps = 86/891 (9%)
Frame = +1
Query: 3325 QKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVD-EATMLQDL 3501
+K+M +M+ ++ +E++ R + E E + L + K D+ +V EA L D
Sbjct: 797 EKEMANMKEEFEKTKEELAKSEAKRKELE----EKMVSLLQEKNDLQLQVQAEADGLADA 852
Query: 3502 MSRKDEEVNA-----------TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKK 3648
R D+ + T+RA ++ + M ++ +K K + EL I+ +
Sbjct: 853 EERCDQLIKTKIQLEAKIKELTERAEDEEE--MNAELTAKKRKLEDECSELKKDIDDLEL 910
Query: 3649 QRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRK-IHEAHLMEIQANLAESDEHKR 3825
+++EK+++ + + ++ +E+A L + A + K++K + EAH + AE D+
Sbjct: 911 TLAKVEKEKHATENKVKNLTEEMAALDETIAKLTKEKKALQEAHQQTLDDLQAEEDK-VN 969
Query: 3826 TLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANIN 4005
TL + ++D L E+E+ +++R A
Sbjct: 970 TLTKAKTKLEQQVDDLEGSLEQEKKLRMDLER------------------------AKRK 1005
Query: 4006 RARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNL 4185
L+ + + +D + + + L L+K+ Q +++ + E+++ QL++ K+
Sbjct: 1006 LEGDLKMTQESTMDLENDKQQLDEKLKKKDFEISQI--QSKIEDEQALGMQLQKKIKELQ 1063
Query: 4186 RDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMA 4365
+E L++++E ++ + + + + +ELE+ S LE + KK E++
Sbjct: 1064 ARIEELEEEIEAERTSRAKAEKHRADLSRELEEISERLEEAGGATAAQIDMNKKREAEFQ 1123
Query: 4366 EERVAVQKALLDRDAMSQELRDRETRVLSLLNE-VDIMKEHLEESDRVRRSLQQELQDSI 4542
+ R +++A L +A + LR + + L E +D ++ ++ ++ + L+ E+ D
Sbjct: 1124 KMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDDLA 1183
Query: 4543 SNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQ--IAEDARLRLEVTNQALKSE 4716
SN + K LEK RSLE +L++++ + EE + + A+ ARL+ E E
Sbjct: 1184 SNMESVSKAKANLEKMCRSLEDQLSEIKTKEEEQQRTINDISAQKARLQTE------SGE 1237
Query: 4717 SDRAISNKDVEAEEKRRG---LLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQ 4887
R + KD + RG +QI +L+ LE E + K+ + + L +Q
Sbjct: 1238 YSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKNALAHALQSARHDCDLLREQ 1297
Query: 4888 LEVANRLKEEYXXXXXXXXXXXXEYQIE--------CEEARQAKEDIAALLREADRKFRA 5043
E K E +++ + EE +AK+ +A L++A+ A
Sbjct: 1298 YEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEA 1357
Query: 5044 V-------EAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQ 5202
V E +++L+ E LM ++ + I SE K++ E A+
Sbjct: 1358 VNSKCASLEKTKQRLQNEVEDLMIDVERSNAACAALDKKQKNFDKILSEWKQKYEETQAE 1417
Query: 5203 XXXXXXXXQS-----------------NCELAIDKQRKAQVQLEQITTDLSMERTLNQKT 5331
+S + E + + Q ++ +T ++ +
Sbjct: 1418 LEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKAIHEL 1477
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRA----RAQMAALEAK----------------- 5448
E K+ +E+ + +A + E E+ + R Q+ + K
Sbjct: 1478 EKVKKQIEQEKSELQAALEEAEASLEHEEGKILRVQLELNQVKSDIDRKIAEKDEEIDQL 1537
Query: 5449 -------VQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKS 5607
V ++ L+ E + + A R +++E LN+ Q R +A++ L +
Sbjct: 1538 KRNHLRVVDSMQSTLDAEIRSRNEALRLKKKMEGDLNEIEIQLSHANRQAAEAQKNLRNT 1597
Query: 5608 NLKNRNLRRQLDEA-------EDEMSRERTKHRNVQREADDLLDANEQLTR 5739
++ + LD+A +++++ + +Q E ++L A EQ R
Sbjct: 1598 QGVLKDTQIHLDDALRSQEDLKEQVAMVERRANLLQAEIEELRAALEQTER 1648
Score = 118 bits (295), Expect = 2e-24
Identities = 174/910 (19%), Positives = 360/910 (39%), Gaps = 132/910 (14%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ T+E + +E+D ++ ++KL + E + IQ +++ E +L LQ
Sbjct: 1004 RKLEGDLKMTQESTMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQ 1063
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + +R S R ++E + + +
Sbjct: 1064 ARIEELEEEIE--AERTSRAKAEKHRADLSR--ELEEISERLEEAGGATAAQIDMNKKRE 1119
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K L+
Sbjct: 1120 AEFQKMRRDLEEATLQHEATAAALRKKHADSTAELG---EQIDNLQRVKQKLEKEKSELK 1176
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K+ LE+ R L +L + K E+ + +++ Q + E
Sbjct: 1177 MEIDDLASNMESVSKAKANLEKMCRSLEDQLSEIKTKEEEQQRTINDISAQKARLQTESG 1236
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ +E+ A ++ + + + I+EL+ +E E A+N + + ++
Sbjct: 1237 EYSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKNALAHALQSARHDCDLLRE 1296
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQ 3630
++ + LQ +S+ + EV TK + IQ T E +EE K K ++++++ +
Sbjct: 1297 QYEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQDAEEH 1354
Query: 3631 IEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLME-------I 3789
+E + + LEK + + E D+ ++ A+ A +DKK+K + L E
Sbjct: 1355 VEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACAALDKKQKNFDKILSEWKQKYEET 1414
Query: 3790 QANLAESDEHKRTL--------------IDQLERSRDE---------------------L 3864
QA L S + R+L +D LE + E +
Sbjct: 1415 QAELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKAI 1474
Query: 3865 DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKI----ANINRARQLEDE- 4029
L +V+++ E + +Q L A +L++ ++I+R +DE
Sbjct: 1475 HELEKVKKQIEQEKSELQAALEEAEASLEHEEGKILR-VQLELNQVKSDIDRKIAEKDEE 1533
Query: 4030 -------------------------KNALLDEKEEAEGLRAHLEKEIHAARQGAGEARR- 4131
+N L K++ EG +E ++ A + A EA++
Sbjct: 1534 IDQLKRNHLRVVDSMQSTLDAEIRSRNEALRLKKKMEGDLNEIEIQLSHANRQAAEAQKN 1593
Query: 4132 -------------------KAEESVNQQLEEL-RKKNLRDVEHLQKQLEESEVAKERILQ 4251
+++E + +Q+ + R+ NL LQ ++EE A E+ +
Sbjct: 1594 LRNTQGVLKDTQIHLDDALRSQEDLKEQVAMVERRANL-----LQAEIEELRAALEQTER 1648
Query: 4252 SKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRD 4431
S+K +QEL D+S ++ + + +KK ES +++ + ++ + QE R+
Sbjct: 1649 SRKVAEQELLDASERVQLLHTQNTSLINTKKKLESDISQIQSEMEDTI-------QEARN 1701
Query: 4432 RETRVLSLLNEVDIMKEHLEES-------DRVRRSLQQELQDSISNKDDFG--------K 4566
E + + + +M E L++ +R++++L Q ++D D+ K
Sbjct: 1702 AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLDQTVKDLQHRLDEAEQLALKGGKK 1761
Query: 4567 NVHELEKAKRSLEAELN---------------------DMRVQMEELEDNLQIAEDARLR 4683
+ +LE R LE E++ ++ Q EE N+ +D +
Sbjct: 1762 QIQKLEARVRELEGEVDAEQKRSAEAVKGVRKYERRVKELTYQSEEDRKNVLRLQDLVDK 1821
Query: 4684 LEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIEN 4863
L++ ++ K +++ EAEE L + R +++ELE + A S K+
Sbjct: 1822 LQMKVKSYKRQAE--------EAEELSNVNLSKFRKIQHELEEAEERADIAESQVNKLRA 1873
Query: 4864 QIGELEQQLE 4893
+ E+ ++ E
Sbjct: 1874 KSREIGKKAE 1883
Score = 98.6 bits (244), Expect = 2e-18
Identities = 119/580 (20%), Positives = 250/580 (42%), Gaps = 38/580 (6%)
Frame = +1
Query: 3046 DHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMG 3225
D +R + +AK +L +L + E+ + + LE+ K++L E+ED +
Sbjct: 1329 DAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNA 1388
Query: 3226 KVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNK 3405
L+ + D+ L +Y+E A + QK+ R + T + +++ E +
Sbjct: 1389 ACAALDKKQKNFDKILSEWKQKYEETQAELEASQKESRSLSTELFKMKNAYEESLDHLET 1448
Query: 3406 AEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTM---EGK 3576
+ + + ++ + + + L+ + + ++E + + A+E+ + ++ EGK
Sbjct: 1449 LKRENKNLQQEISDLTEQIAEGGKAIHELEKVKKQIEQEKSELQAALEEAEASLEHEEGK 1508
Query: 3577 I-------EEQKAKFSRQVEELHDQIEQHKKQRSQ-LEKQQNQADQERADMAQEIALLQA 3732
I + K+ R++ E ++I+Q K+ + ++ Q+ D E + + L +
Sbjct: 1509 ILRVQLELNQVKSDIDRKIAEKDEEIDQLKRNHLRVVDSMQSTLDAEIRSRNEALRLKKK 1568
Query: 3733 SRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFAN 3912
D+++ E L AE+ ++ R L+ ++ LD R +E+ + A
Sbjct: 1569 MEGDLNE----IEIQLSHANRQAAEAQKNLRNTQGVLKDTQIHLDDALRSQEDLKEQVAM 1624
Query: 3913 MQRR--LATAXXXXXXXXXXXXXXTRLKIAN------INRARQLEDEKNALLDEKEEAEG 4068
++RR L A +R K+A R + L + +L++ K++ E
Sbjct: 1625 VERRANLLQAEIEELRAALEQTERSR-KVAEQELLDASERVQLLHTQNTSLINTKKKLES 1683
Query: 4069 ----LRAHLEKEIHAARQGAGEARR------------KAEESVNQQLEELRKKNLRDVEH 4200
+++ +E I AR +A++ K E+ + LE ++K + V+
Sbjct: 1684 DISQIQSEMEDTIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLDQTVKD 1743
Query: 4201 LQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVA 4380
LQ +L+E+E + L+ KK Q+LE ELE D+E+++ AE
Sbjct: 1744 LQHRLDEAE---QLALKGGKKQIQKLEARVRELE----GEVDAEQKRS------AEAVKG 1790
Query: 4381 VQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDF 4560
V+K ++ + + VL L + VD ++ ++ +R ++ + S N F
Sbjct: 1791 VRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQMKVKS---YKRQAEEAEELSNVNLSKF 1847
Query: 4561 GKNVHELEKAKRS---LEAELNDMRVQMEELEDNLQIAED 4671
K HELE+A+ E+++N +R + E+ + ED
Sbjct: 1848 RKIQHELEEAEERADIAESQVNKLRAKSREIGKKAESTED 1887
Score = 93.6 bits (231), Expect = 5e-17
Identities = 118/533 (22%), Positives = 225/533 (42%), Gaps = 22/533 (4%)
Frame = +1
Query: 3289 RYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLD 3468
+Y E A + QK+ R + T I +++ E ++ E RRE L++ D+ +
Sbjct: 2769 KYQESQAELEAAQKESRTLSTEIFQMKNAYE---EVLDQVETVRRE-NKNLQQEISDLTE 2824
Query: 3469 KVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELH-------- 3624
++ EA + + ++ K ++ EG +E ++ K R EL+
Sbjct: 2825 QLAEAGKASHGLEKAKKQTEQEKYDLQAALEEAEGSLEHEEGKILRVQLELNQVKSDVDR 2884
Query: 3625 ------DQIEQHKKQRSQ-LEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLM 3783
++I+Q KK + LE Q D E + L + D++ E L
Sbjct: 2885 RSAEKDEEIQQLKKNHQRVLESMQTTLDAEIRSRNDALRLKKKMEGDLNDM----EIQLS 2940
Query: 3784 EIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXX 3963
+AE+ +H + + QL+ S+ LD R ++ + A ++RR
Sbjct: 2941 RANCQVAETQKHLKVVQGQLKDSQLHLDDALRENDDLKEQLAVIERR------------- 2987
Query: 3964 XXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEE 4143
N +LE + AL E+ E R E+E+ A + R +
Sbjct: 2988 -----------NNLMMTELEQMRAAL----EQTERARKVSEQELTDASE-----RVQILH 3027
Query: 4144 SVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHR 4323
S N L +KK D+ HLQ ++E+S + +++K ++ + D++M E ++
Sbjct: 3028 SQNTSLLNTKKKLEVDITHLQNEVEDS---IQEARNAEEKAKKAITDAAMMAEELKKEQD 3084
Query: 4324 DSE--KRQKKFESQMAEERVAVQKALLDRDAMS-----QELRDRETRVLSLLNEVDIMKE 4482
S +R K+ QM ++ +Q L + + ++ ++L+ E R+ L NE+DI ++
Sbjct: 3085 TSAHLERMKRNLEQMVKD---LQHRLDEAEQLALKGGKKQLQKLEARIHELENELDIEQK 3141
Query: 4483 HLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQI 4662
ES + R ++ L++ ++ KN+ L+ L+ ++ + Q EE E+
Sbjct: 3142 RGTESLKGARKYERRLKELTYQSEEDKKNILRLQNLVDKLQLKVKAYKKQAEEAEEQ--- 3198
Query: 4663 AEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKR 4821
A R T L+ +RA D+ AE + L + RD+ + +E+R
Sbjct: 3199 ASTNLSRCRKTQHELEEAEERA----DI-AECQVNKLRAKSRDVGRQCHHERR 3246
Score = 85.9 bits (211), Expect = 1e-14
Identities = 95/455 (20%), Positives = 193/455 (41%), Gaps = 43/455 (9%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L QL E + + + K + EQ K L A LE+++ L + GK+ + +L + +
Sbjct: 2822 LTEQLAEAGKASHGLEKAKKQTEQEKYDLQAALEEAEGSLEHEEGKILRVQLELNQVKSD 2881
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ + DEE +Q+ ++ Q ++ ++ ++ E +RN A ++ K+
Sbjct: 2882 VDRRSAEKDEE------IQQLKKNHQRVLESMQTTLDAEIRSRNDALRLKK-------KM 2928
Query: 3451 KGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK-------------IEEQK 3591
+GD+ D ++ +SR + +V T++ ++ +Q ++ ++EQ
Sbjct: 2929 EGDLND-------MEIQLSRANCQVAETQKHLKVVQGQLKDSQLHLDDALRENDDLKEQL 2981
Query: 3592 AKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHE 3771
A R+ + ++EQ + Q E+ + ++QE D ++ + +L + + +K E
Sbjct: 2982 AVIERRNNLMMTELEQMRAALEQTERARKVSEQELTDASERVQILHSQNTSLLNTKKKLE 3041
Query: 3772 AHLMEIQANLAESDEHKRT--------------LIDQLERSRDELDHLNRVREEEEHAFA 3909
+ +Q + +S + R + ++L++ +D HL R++ E
Sbjct: 3042 VDITHLQNEVEDSIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKRNLEQMVK 3101
Query: 3910 NMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEK 4089
++Q RL A +I +LE+E + +++K E L+
Sbjct: 3102 DLQHRLDEAEQLALKGGKKQLQKLEARI------HELENELD--IEQKRGTESLK----- 3148
Query: 4090 EIHAARQGAGEARRKAEESVNQQLEE----LRKKNLRD-----VEHLQKQLEESEVAKER 4242
GA + R+ +E Q E+ LR +NL D V+ +KQ EE+E
Sbjct: 3149 -------GARKYERRLKELTYQSEEDKKNILRLQNLVDKLQLKVKAYKKQAEEAEEQAST 3201
Query: 4243 ILQSKKKIQQELED-------SSMELENVRASHRD 4326
L +K Q ELE+ + ++ +RA RD
Sbjct: 3202 NLSRCRKTQHELEEAEERADIAECQVNKLRAKSRD 3236
Score = 78.6 bits (192), Expect = 2e-12
Identities = 92/456 (20%), Positives = 179/456 (39%), Gaps = 90/456 (19%)
Frame = +1
Query: 3985 LKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEA--RRKAEESVNQQ 4158
L I R+R ++ + + +++ + +A LE +R + E + A E V Q
Sbjct: 2745 LSACRIQRSRLRLSIRSVMAEWRQKYQESQAELEAAQKESRTLSTEIFQMKNAYEEVLDQ 2804
Query: 4159 LEELRKKNL---RDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDS 4329
+E +R++N +++ L +QL E+ A + ++KK+ +QE D LE S
Sbjct: 2805 VETVRRENKNLQQEISDLTEQLAEAGKASHGLEKAKKQTEQEKYDLQAALEEAEGSLEHE 2864
Query: 4330 EKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSL------------------ 4455
E + + + ++ + + V + ++D Q+L+ RVL
Sbjct: 2865 EGKILRVQLELNQVKSDVDRRSAEKDEEIQQLKKNHQRVLESMQTTLDAEIRSRNDALRL 2924
Query: 4456 -------LNEVDIM-----------KEHLEESDRVRRSLQQELQDSISNKDDFGKNVHEL 4581
LN+++I ++HL+ + Q L D++ DD + + +
Sbjct: 2925 KKKMEGDLNDMEIQLSRANCQVAETQKHLKVVQGQLKDSQLHLDDALRENDDLKEQLAVI 2984
Query: 4582 EKAKRSLEAELNDMRVQME----------------------------------------- 4638
E+ + EL MR +E
Sbjct: 2985 ERRNNLMMTELEQMRAALEQTERARKVSEQELTDASERVQILHSQNTSLLNTKKKLEVDI 3044
Query: 4639 -----ELEDNLQIAEDA--RLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLE 4797
E+ED++Q A +A + + +T+ A+ +E + + E +R L + ++DL+
Sbjct: 3045 THLQNEVEDSIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKRNLEQMVKDLQ 3104
Query: 4798 NEL-ENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIEC 4974
+ L E E+ G +K+E +I ELE +L++ + E E +
Sbjct: 3105 HRLDEAEQLALKGGKKQLQKLEARIHELENELDIEQKRGTESLKGARKYERRLKELTYQS 3164
Query: 4975 EEARQAKEDIAALLREADRKFRAVEAEREQLREANE 5082
EE K++I L D+ V+A ++Q EA E
Sbjct: 3165 EE---DKKNILRLQNLVDKLQLKVKAYKKQAEEAEE 3197
Score = 73.2 bits (178), Expect = 7e-11
Identities = 112/567 (19%), Positives = 224/567 (38%), Gaps = 5/567 (0%)
Frame = +1
Query: 4057 EAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLE-----E 4221
E+E A++++E ++ ++ K +E + + L++KN D++ LQ Q E +
Sbjct: 795 ESEKEMANMKEEFEKTKEELAKSEAKRKELEEKMVSLLQEKN--DLQ-LQVQAEADGLAD 851
Query: 4222 SEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLD 4401
+E ++++++K +++ ++++ + E+ + + +++K E + +E + + L
Sbjct: 852 AEERCDQLIKTKIQLEAKIKELTERAEDEEEMNAELTAKKRKLEDECSELKKDIDDLELT 911
Query: 4402 RDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHEL 4581
+ +E E +V +L E+ + E + + + +++LQ+ Q ++ + V+ L
Sbjct: 912 LAKVEKEKHATENKVKNLTEEMAALDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 971
Query: 4582 EKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEK 4761
KAK LE +++D LE +L+ + R+ LE A+ K
Sbjct: 972 TKAKTKLEQQVDD-------LEGSLEQEKKLRMDLE-------------------RAKRK 1005
Query: 4762 RRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXX 4941
G LK ++ +LEN+K QQL+ +LK++
Sbjct: 1006 LEGDLKMTQESTMDLENDK---------------------QQLD--EKLKKK-------- 1034
Query: 4942 XXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXX 5121
E + + ED AL + +K + ++A E+L E E
Sbjct: 1035 -------DFEISQIQSKIEDEQALGMQLQKKIKELQARIEELEEEIEA------------ 1075
Query: 5122 XXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDL 5301
RAK ++ R LE + +LE+
Sbjct: 1076 --ERTSRAKAEKHRADLSRELE-------------------------EISERLEEAGGAT 1108
Query: 5302 SMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVE 5481
+ + +N+K EAE Q + R +LE A + A AAL K D
Sbjct: 1109 AAQIDMNKKREAEFQKMRR----------DLEE-ATLQHEATAAALRKK---HADSTAEL 1154
Query: 5482 GQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEM 5661
G++ R ++LEK ++ + +D +E + NL + ED++
Sbjct: 1155 GEQIDNLQRVKQKLEKEKSELKMEIDD-------LASNMESVSKAKANLEKMCRSLEDQL 1207
Query: 5662 SRERTKHRNVQREADDLLDANEQLTRE 5742
S +TK QR +D+ +L E
Sbjct: 1208 SEIKTKEEEQQRTINDISAQKARLQTE 1234
Score = 68.9 bits (167), Expect = 1e-09
Identities = 100/558 (17%), Positives = 210/558 (36%), Gaps = 16/558 (2%)
Frame = +1
Query: 2545 TDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDI 2724
T E+ A E R+ L KM++ + E+ L+ + E +Q+++ +E AE
Sbjct: 1414 TQAELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKA 1473
Query: 2725 RGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXX 2904
L+ +++E ++++ L ++ + +R
Sbjct: 1474 IHELEKVKKQIEQEKSELQAALEEAEASL------EHEEGKILRVQLELNQVKSDIDRKI 1527
Query: 2905 XXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKH-GVKA 3081
+DQ Q LD E R+++ ++
Sbjct: 1528 AEKDEEIDQLKRNHLRVVDSMQST----------------------LDAEIRSRNEALRL 1565
Query: 3082 KGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKR 3261
K ++E L+E+E L+ + +E +++ R L+D++ HL + + E+L Q
Sbjct: 1566 KKKMEGDLNEIEIQLSHANRQAAEAQKNLRNTQGVLKDTQIHLDDALRSQEDLKEQ---- 1621
Query: 3262 DEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQL 3441
V +++++ +Q I+ELR +E +R AE
Sbjct: 1622 -----------------VAMVERRANLLQAEIEELRAALEQTERSRKVAEQ--------- 1655
Query: 3442 EKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRA---IEQIQHTMEGKIEEQK---AKFS 3603
+ +D + +Q L ++ +N K+ I QIQ ME I+E + K
Sbjct: 1656 --------ELLDASERVQLLHTQNTSLINTKKKLESDISQIQSEMEDTIQEARNAEEKAK 1707
Query: 3604 RQVEELHDQIEQHKKQR---SQLEKQQNQADQ------ERADMAQEIALLQASRADIDKK 3756
+ + + E+ KK++ + LE+ + DQ R D A+++AL + + I K
Sbjct: 1708 KAITDAAMMAEELKKEQDTSAHLERMKKNLDQTVKDLQHRLDEAEQLAL-KGGKKQIQKL 1766
Query: 3757 RKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATA 3936
EA + E++ + + + + + + L EE+ +Q +
Sbjct: 1767 ----EARVRELEGEVDAEQKRSAEAVKGVRKYERRVKELTYQSEEDRKNVLRLQDLVDKL 1822
Query: 3937 XXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGA 4116
L N+++ R+++ E L+E EE + E +++ R +
Sbjct: 1823 QMKVKSYKRQAEEAEELSNVNLSKFRKIQHE----LEEAEERADIA---ESQVNKLRAKS 1875
Query: 4117 GEARRKAEESVNQQLEEL 4170
E +KAE + + + ++
Sbjct: 1876 REIGKKAESTEDDGIYQI 1893
Score = 54.7 bits (130), Expect = 3e-05
Identities = 71/329 (21%), Positives = 136/329 (40%), Gaps = 31/329 (9%)
Frame = +1
Query: 4852 KIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADR 5031
KI+ + E + E+AN +KEE+ + ++ +E + +LL+E +
Sbjct: 786 KIKPLLKSAESEKEMAN-MKEEFEKTKEELAKSEAK-------RKELEEKMVSLLQEKND 837
Query: 5032 KFRAVEAEREQLREANEG---LMQARKQXXXXXXXXXXXRAKGGGISSE---EKRRLEAK 5193
V+AE + L +A E L++ + Q +++E +KR+LE +
Sbjct: 838 LQLQVQAEADGLADAEERCDQLIKTKIQLEAKIKELTERAEDEEEMNAELTAKKRKLEDE 897
Query: 5194 IAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEA----EKQSLERS 5361
++ + EL + K K + E +L+ E +T A EK++L+ +
Sbjct: 898 CSELKKDI----DDLELTLAKVEKEKHATENKVKNLTEEMAALDETIAKLTKEKKALQEA 953
Query: 5362 NRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLND 5541
++ + E + +A+ LE +V LE L E + + RA R+LE L
Sbjct: 954 HQQTLDDLQAEEDKVNTLTKAK-TKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKM 1012
Query: 5542 TTQQFEDEKRANEQAKELLEKSNL---------------------KNRNLRRQLDEAEDE 5658
T + D + +Q E L+K + K + L+ +++E E+E
Sbjct: 1013 TQESTMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQARIEELEEE 1072
Query: 5659 MSRERTKHRNVQREADDLLDANEQLTREL 5745
+ ERT ++ DL E+++ L
Sbjct: 1073 IEAERTSRAKAEKHRADLSRELEEISERL 1101
>gi|3660091|pdb|1BR2|A Chain A, Smooth Muscle Myosin Motor Domain
Complexed With Mgadp.Alf4
gi|3660092|pdb|1BR2|B Chain B, Smooth Muscle Myosin Motor Domain
Complexed With Mgadp.Alf4
gi|3660093|pdb|1BR2|C Chain C, Smooth Muscle Myosin Motor Domain
Complexed With Mgadp.Alf4
gi|3660094|pdb|1BR2|D Chain D, Smooth Muscle Myosin Motor Domain
Complexed With Mgadp.Alf4
gi|3660095|pdb|1BR2|E Chain E, Smooth Muscle Myosin Motor Domain
Complexed With Mgadp.Alf4
gi|3660096|pdb|1BR2|F Chain F, Smooth Muscle Myosin Motor Domain
Complexed With Mgadp.Alf4
Length = 791
Score = 1040 bits (2690), Expect = 0.0
Identities = 518/791 (65%), Positives = 636/791 (79%), Gaps = 8/791 (1%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
D ++L V + V +P A W+ +KL WVP + GF SIK E DEV VEL + ++V
Sbjct: 8 DEKFLFVDKNFVNNPLAQADWSAKKLVWVPSEKHGFEAASIKEEKGDEVTVELQENGKKV 67
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
T+S+DD+QK NPPKF K+EDM+ELT LNEASVLHNL++RY+S LIYTYSGLFCVVINPYK
Sbjct: 68 TLSKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVINPYK 127
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
+LPIYSE +I+ +KGKKRHEMPPHI+AIADTAYRSMLQ+REDQSILCTGESGAGKTENTK
Sbjct: 128 QLPIYSEKIIDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTK 187
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVIQYLA VA + + K +I Q P GELE QLLQANPILEAFGN+KTVK
Sbjct: 188 KVIQYLAVVASSHKGKK-----DTSITQGPSFS--YGELEKQLLQANPILEAFGNAKTVK 240
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
NDNSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+DER+FHIFY ++ G S +
Sbjct: 241 NDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQAKDERTFHIFYYLIAGASEQM 300
Query: 907 KSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLL 1086
+++ LLEG +NY FL N + +P D + F T+ +M IMGF ++E +SI+RVVS+VL
Sbjct: 301 RNDLLLEGFNNYTFLSNGHVPIPAQQDDEMFQETLEAMTIMGFTEEEQTSILRVVSSVLQ 360
Query: 1087 LGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQE 1266
LGN+ F +E+ +DQA + D+ QKVCHL+G+ V + ++ L PRIKVGR+ V KAQ +E
Sbjct: 361 LGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKE 420
Query: 1267 QAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQIC 1446
QA+FA+EA+AKA +ERLF+W++TR+NK+LD+T RQGASF+GILDIAGFEIF+INSFEQ+C
Sbjct: 421 QADFAIEALAKAKFERLFRWILTRVNKALDKTKRQGASFLGILDIAGFEIFEINSFEQLC 480
Query: 1447 INYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALL 1617
INYTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP I+LIE+P GVLALL
Sbjct: 481 INYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPTNPPGVLALL 540
Query: 1618 DEECLFPKANDKSFVEKLQKTHNKHPKF-IVPDMRSKSHFAVVHYAGRVDYSADQWLMKN 1794
DEEC FPKA D SFVEKL + H KF ++ K+ F ++HYAG+V Y+A WL KN
Sbjct: 541 DEECWFPKATDTSFVEKLIQEQGNHAKFQKSKQLKDKTEFCILHYAGKVTYNASAWLTKN 600
Query: 1795 MDPLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQ 1962
MDPLN+NV L+ S+D FVA +WKD + G+ A+M E++ +++KGMFRTV Q
Sbjct: 601 MDPLNDNVTSLLNQSSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQ 660
Query: 1963 LHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGF 2142
L+KEQLTKLMTTLRNT+P+FVRCIIPNHEK++GK++++LVLEQLRCNGVLEGIRICRQGF
Sbjct: 661 LYKEQLTKLMTTLRNTNPNFVRCIIPNHEKRAGKLDAHLVLEQLRCNGVLEGIRICRQGF 720
Query: 2143 PNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVL 2322
PNR+ FQEFR RYEIL + IPK F+DGK++ MI AL++D NLYRIGQSK+FFRTGVL
Sbjct: 721 PNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVL 780
Query: 2323 AHLEEERDLKL 2355
AHLEEERDLK+
Sbjct: 781 AHLEEERDLKI 791
>gi|39582764|emb|CAE74227.1| Hypothetical protein CBG21911
[Caenorhabditis briggsae]
Length = 1938
Score = 1019 bits (2634), Expect = 0.0
Identities = 617/1917 (32%), Positives = 1015/1917 (52%), Gaps = 23/1917 (1%)
Frame = +1
Query: 13 QYLQVQRAA-VADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVT 189
QYL+ R +AD + + +K W+PD EG++ G IK V + + VT
Sbjct: 12 QYLKRSREQQLADQSR--PYDSKKNVWIPDPEEGYIEGEIKGPGPKADTVIVTAGGKDVT 69
Query: 190 ISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKK 369
+ +D VQ+ NPPKF+K EDMS LT+LN+ASVL NL+ RY + LIYTYSGLFCVVINPYK+
Sbjct: 70 LKKDIVQEMNPPKFEKTEDMSNLTFLNDASVLWNLRSRYAAMLIYTYSGLFCVVINPYKR 129
Query: 370 LPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKK 549
LPIY++ + F GK+R EMPPH+FA++D AYR+MLQ+ E+QS+L TGESGAGKTENTKK
Sbjct: 130 LPIYTDSVARMFMGKRRTEMPPHLFAVSDEAYRNMLQDHENQSMLITGESGAGKTENTKK 189
Query: 550 VIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKN 729
VI Y A V + + +P LE Q++Q NP+LEAFGN+KTV+N
Sbjct: 190 VIAYFATVGASQK-------------AQPKEGEKTVTLEDQIVQTNPVLEAFGNAKTVRN 236
Query: 730 DNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEK 909
+NSSRFGKFIRI+F+ G ++ +IE YLLEKSRV+RQA ER +HIFYQI + +
Sbjct: 237 NNSSRFGKFIRIHFNKYGTLASCDIEHYLLEKSRVIRQAPGERCYHIFYQIFSDFKPQLR 296
Query: 910 SEYLLEG-VDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLL 1086
+E LL+ + +Y F+ + + +DD +EF T + ++ F++ E R++S +
Sbjct: 297 NELLLDKPIADYWFVAQAELLIDGIDDTEEFQLTDEAFDVLKFSETEKMDCYRLMSGHMH 356
Query: 1087 LGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQE 1266
+GN++F Q + +QA +K C + G+ + KA + PR+KVG E+V+K QN +
Sbjct: 357 MGNMKFKQRPREEQAEPDGQDEAEKACAMFGVDADQFLKALVSPRVKVGTEWVSKGQNVD 416
Query: 1267 QAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQIC 1446
Q +A+ A+AK Y R+F WLV + N +LD+ FIG+LDIAGFEIFD NSFEQ+
Sbjct: 417 QVHWAIGAMAKGLYARVFNWLVKKCNLTLDQKGIDRDYFIGVLDIAGFEIFDFNSFEQLW 476
Query: 1447 INYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEE 1626
IN+ NEKLQQ FN+ MF+LEQEEY REGI+W FIDFGLDLQ I+LIEKP+G++++LDEE
Sbjct: 477 INFVNEKLQQFFNHHMFVLEQEEYAREGIQWTFIDFGLDLQACIELIEKPLGIISMLDEE 536
Query: 1627 CLFPKANDKSFVEKLQKTH-NKHPKFIVP----DMRSKSHFAVVHYAGRVDYSADQWLMK 1791
C+ PKA D + +KL H KHP F P + ++HFA+ HYAG V Y+ WL K
Sbjct: 537 CIVPKATDMTLAQKLTDQHLGKHPNFEKPKPPKGKQGEAHFAMRHYAGTVRYNVLNWLEK 596
Query: 1792 NMDPLNENVVGLMQNS-TDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLH 1968
N DPLN+ VV +M+ S + + IW+D AA + G F TVS ++
Sbjct: 597 NKDPLNDTVVSVMKASKKNDLLVEIWQDYTTQEEAAAAAKSGGGRKGGKSGSFMTVSMMY 656
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
+E L KLMT L T PHF+RCIIPN +K+SG I++ LVL QL CNGVLEGIRICR+GFPN
Sbjct: 657 RESLNKLMTMLHKTHPHFIRCIIPNEKKQSGMIDAGLVLNQLTCNGVLEGIRICRKGFPN 716
Query: 2149 RVPFQEFRHRYEILTPDVIPKNFIDGKES----VRKMITALDIDTNLYRIGQSKVFFRTG 2316
R +F HRY IL K+ D K + ++ +I A ++ +RIG +KVFF+ G
Sbjct: 717 RTLHPDFVHRYAILAAKE-AKSSDDPKTAAGAILQSLINAKKLNDEQFRIGHTKVFFKAG 775
Query: 2317 VLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQ 2496
V+AH+E+ RD KL +I FQ+ R + + N ++ LR W
Sbjct: 776 VVAHIEDLRDEKLNQIITGFQSAIRWYTATADAGARRKQLNSYIILQRNIRSWCVLRTWD 835
Query: 2497 WWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQ 2676
W+ LF K++P L+ + +E+ +E + + K E + E+ ++ ER+ +
Sbjct: 836 WFLLFGKIRPQLKCGKMAEEMAKMAEEQKVLEVEAKKAEAARKAQEEAYAKLSAERSKLL 895
Query: 2677 EQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVR 2856
E L+ SA +++ RL + QE+E +ND DRLS RRK + V
Sbjct: 896 EALELTQGGSAAIEEKLTRLNSARQEVEKSLNDANDRLSEHEEKNADLEKQRRKAQQEVE 955
Query: 2857 DXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTT 3036
+ +K + + L
Sbjct: 956 NLKKSIEAVDGNLSRSLEEKAAKENQIRSLQDEMNSQDETIGKINKEKKHLEENNRQLID 1015
Query: 3037 QLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAE 3216
L E + + +G+LE L E+E+ + RE++ ++E E+ KRK+ EL+ +++ + E
Sbjct: 1016 DLQAEEAKQAQANRLRGKLEQTLDEMEEAVEREKRIRAETEKSKRKVEGELKGAQESIDE 1075
Query: 3217 KMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNA 3396
E + L K++ ++ R ++E A + +Q ++ I E+ +++E ER +
Sbjct: 1076 LTAIKLEADASLKKKEADIHALGVRIEDEQALANRLTRQSKENAQRIIEIEDELEHERQS 1135
Query: 3397 RNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK 3576
R+KA+ R E+ +L+++ + ++ + + Q+ +KD E+ +R +++ E +
Sbjct: 1136 RSKADRARAELQRELDELNERLDEQNKQLEIQQENNKKKDSEIIKFRRDLDEKNMANEDQ 1195
Query: 3577 IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKK 3756
+ + K + Q+++L + ++ +K ++++EK++ +E D+ ++ SR + ++
Sbjct: 1196 MAMIRRKNNDQIQDLTNTLDALQKGKAKIEKEKGVLQKELDDINAQVDQETKSRVEQERL 1255
Query: 3757 RKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATA 3936
K +E + E+Q + E R ++ L R EE E A + R
Sbjct: 1256 AKQYEIQVAELQQKVDEQTRQITEFTSTKGRLSNDNSDLARQVEELEIHLATINRAKTAF 1315
Query: 3937 XXXXXXXXXXXXXXTRLKIANINRARQLE---DEKNALLDE----KEEAEGLRAHLEKEI 4095
+ + LE D+ + LL+E K++ + + + EI
Sbjct: 1316 SSQLVEAKKAAEDELHERQEFHAACKNLEHELDQCHELLEEQINGKDDIQRQLSRINSEI 1375
Query: 4096 HAARQGAGEARRKAEESV-NQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQ 4272
+AR + E V +++LEEL++K + V LQ+ L ++ + ++K K+
Sbjct: 1376 -----SQWKARYEGEGLVGSEELEELKRKQMNRVMDLQEALSAAQNKVISLEKAKGKLLA 1430
Query: 4273 ELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLS 4452
E ED+ +++ EK+Q+ F+ + + + V + DA +++ R+ T V
Sbjct: 1431 ETEDARSDVDRHLTVIASLEKKQRAFDKIVDDWKRKVDDIQKEIDATTRDSRNTSTEVFK 1490
Query: 4453 LLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQ 4632
L + +D + E +E R + QE++D G+ E+ K+ R LE E ++++
Sbjct: 1491 LRSSMDNLSEQIETLRRENKIYSQEIRDINEQITQGGRTYQEVHKSVRRLEQEKDELQHA 1550
Query: 4633 MEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELEN 4812
++E E L+ E LRL++ Q ++SE ++ I K+ E E R+ + + ++ LE
Sbjct: 1551 LDEAEAALEAEESKVLRLQIEVQQIRSEIEKRIQEKEEEFENTRKNHQRALESIQASLET 1610
Query: 4813 EKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQA 4992
E + K+ +KK+E I +LE L+ AN+ + E Q + ++ ++
Sbjct: 1611 EAKSKAELARAKKKLETDINQLEIALDHANKANVDAQKNLKKLFDQVKELQGQVDDEQRR 1670
Query: 4993 KEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAK---GGGIS 5163
+E+I A+++ +E E L + + +KQ +
Sbjct: 1671 REEIRENYLAAEKRLAVALSESEDLAHRIDASEKHKKQLEIEQAELKSSNTELIGNNAAL 1730
Query: 5164 SEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEK 5343
S KR++E ++ + + + ++ RKA +++ ++ E+ + ++
Sbjct: 1731 SAMKRKVENEVQIARNELDEYLNELKASEERARKAAADADRLAEEVRQEQEHAVHVDRQR 1790
Query: 5344 QSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRL 5523
+SLE + ++ +AKI + E ++ +E +V+ +E +L+ E + A + +
Sbjct: 1791 KSLELNAKELQAKIDDAERAMIQFGAKALSKVEERVRSVEAELHSEQRRHQEAVKGFTKQ 1850
Query: 5524 EKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQ 5694
E+R + Q E++K+A ++ +E +EK K R +RQ++EAE+ ++ +K R +Q
Sbjct: 1851 ERRARELQFQVEEDKKAFDRLQENVEKLQQKIRVQKRQIEEAEEVATQNLSKFRQIQ 1907
Score = 147 bits (371), Expect = 3e-33
Identities = 184/938 (19%), Positives = 393/938 (41%), Gaps = 40/938 (4%)
Frame = +1
Query: 3052 EERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLA---EKM 3222
EE AK + K LE + + E + + ++L + KLL LE ++ A EK+
Sbjct: 854 EEMAKMAEEQKV-LEVEAKKAEAARKAQEEAYAKLSAERSKLLEALELTQGGSAAIEEKL 912
Query: 3223 GKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARN 3402
++ ++ K + +L+ ++E++A+ ++KQ R Q ++ L++ +E
Sbjct: 913 TRLNSARQEVEKSLNDANDRLSEHEEKNAD---LEKQRRKAQQEVENLKKSIEA------ 963
Query: 3403 KAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDE---EVNATKRAIE-------- 3549
V L + + K ++ LQD M+ +DE ++N K+ +E
Sbjct: 964 --------VDGNLSRSLEEKAAKENQIRSLQDEMNSQDETIGKINKEKKHLEENNRQLID 1015
Query: 3550 --QIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIAL 3723
Q + + + + K + ++E+ + +E+ K+ R++ EK + + + E + I
Sbjct: 1016 DLQAEEAKQAQANRLRGKLEQTLDEMEEAVEREKRIRAETEKSKRKVEGELKGAQESIDE 1075
Query: 3724 LQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERS-------RDELDHLNRV 3882
L A + + D K EA + + + + L Q + + DEL+H +
Sbjct: 1076 LTAIKLEADASLKKKEADIHALGVRIEDEQALANRLTRQSKENAQRIIEIEDELEHERQS 1135
Query: 3883 REEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEA 4062
R + + A A +QR L + + DE+N L+ ++E
Sbjct: 1136 RSKADRARAELQREL-------------------------DELNERLDEQNKQLEIQQEN 1170
Query: 4063 EGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKER 4242
+ + EI R+ E E+ Q+ +R+KN ++ L L+ + K +
Sbjct: 1171 NKKK---DSEIIKFRRDLDEKNMANED----QMAMIRRKNNDQIQDLTNTLDALQKGKAK 1223
Query: 4243 ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQE 4422
I + K +Q+EL+D + +++ S + E+ K++E Q+AE +Q+ + ++ E
Sbjct: 1224 IEKEKGVLQKELDDINAQVDQETKSRVEQERLAKQYEIQVAE----LQQKVDEQTRQITE 1279
Query: 4423 LRDRETRVLS----LLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKA 4590
+ R+ + L +V+ ++ HL +R + + +L ++ +D E A
Sbjct: 1280 FTSTKGRLSNDNSDLARQVEELEIHLATINRAKTAFSSQLVEAKKAAEDELHERQEFHAA 1339
Query: 4591 KRSLEAELNDMRVQMEEL---EDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEK 4761
++LE EL+ +EE +D++Q + +R+ E++ + E + + ++ E EE
Sbjct: 1340 CKNLEHELDQCHELLEEQINGKDDIQ-RQLSRINSEISQWKARYEGEGLVGSE--ELEEL 1396
Query: 4762 RRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXX 4941
+R + ++ DL+ L S A + +E G+L + E A + +
Sbjct: 1397 KRKQMNRVMDLQEAL-------SAAQNKVISLEKAKGKLLAETEDARSDVDRHLTVIASL 1449
Query: 4942 XXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXX 5121
+ ++ ++ +DI + R R E +LR + + L + +
Sbjct: 1450 EKKQRAFDKIVDDWKRKVDDIQKEIDATTRDSRNTSTEVFKLRSSMDNLSEQIETLR--- 1506
Query: 5122 XXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDL 5301
+ I S+E R + +I Q + ++ + Q L++ L
Sbjct: 1507 --------RENKIYSQEIRDINEQITQGGRTYQEVHKSVRRLEQEKDELQHALDEAEAAL 1558
Query: 5302 SMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVE 5481
E + + + E Q + + + +I E E ++ + ALE+ ++ L E
Sbjct: 1559 EAEESKVLRLQIEVQQIRS---EIEKRIQEKEEEFENTRKNHQRALES----IQASLETE 1611
Query: 5482 GQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEM 5661
+ K RA ++LE +N + +AN A++ L+K + + L+ Q+D+ +
Sbjct: 1612 AKSKAELARAKKKLETDINQLEIALDHANKANVDAQKNLKKLFDQVKELQGQVDDEQRRR 1671
Query: 5662 SRERTKHRNVQR-------EADDL---LDANEQLTREL 5745
R + ++ E++DL +DA+E+ ++L
Sbjct: 1672 EEIRENYLAAEKRLAVALSESEDLAHRIDASEKHKKQL 1709
>gi|17508449|ref|NP_492053.1| MYOsin heavy chain structural gene,
LEThal LET-75 (223.3 kD) (myo-1) [Caenorhabditis elegans]
gi|11384454|pir||MWKW1 myosin heavy chain D [similarity] -
Caenorhabditis elegans
gi|3876131|emb|CAA95806.1| Hypothetical protein R06C7.10
[Caenorhabditis elegans]
gi|3878843|emb|CAA95848.1| C. elegans LET-75 protein (corresponding
sequence R06C7.10) [Caenorhabditis elegans]
Length = 1938
Score = 1016 bits (2628), Expect = 0.0
Identities = 623/1917 (32%), Positives = 1013/1917 (52%), Gaps = 23/1917 (1%)
Frame = +1
Query: 13 QYLQVQRAA-VADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVT 189
QYL+ R +AD + + +K W+PD EG++ G IK V + + VT
Sbjct: 12 QYLKRSREQQLADQSR--PYDSKKNVWIPDAEEGYIEGVIKGPGPKADTVIVTAGGKDVT 69
Query: 190 ISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKK 369
+ +D VQ+ NPPKF+K EDMS LT+LN+ASVL NL+ RY + LIYTYSGLFCVVINPYK+
Sbjct: 70 LKKDIVQEVNPPKFEKTEDMSNLTFLNDASVLWNLRSRYAAMLIYTYSGLFCVVINPYKR 129
Query: 370 LPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKK 549
LPIY++ + F GK+R EMPPH+FA++D AYR MLQ+ E+QS+L TGESGAGKTENTKK
Sbjct: 130 LPIYTDSVARMFMGKRRTEMPPHLFAVSDQAYRYMLQDHENQSMLITGESGAGKTENTKK 189
Query: 550 VIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKN 729
VI Y A V GA++ +L ++ LE Q++Q NP+LEAFGN+KTV+N
Sbjct: 190 VICYFATV-GASQKAALKEGEKEVT------------LEDQIVQTNPVLEAFGNAKTVRN 236
Query: 730 DNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEK 909
+NSSRFGKFIRI+F+ G ++ +IE YLLEKSRV+RQA ER +HIFYQI + +
Sbjct: 237 NNSSRFGKFIRIHFNKHGTLASCDIEHYLLEKSRVIRQAPGERCYHIFYQIYSDFKPQLR 296
Query: 910 SEYLLEG-VDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLL 1086
E LL + NY F+ + + +DD +EF T + ++ F+ E R++SA +
Sbjct: 297 DELLLNHPISNYWFVAQAELLIDGIDDTEEFQLTDEAFDVLKFSPTEKMDCYRLMSAHMH 356
Query: 1087 LGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQE 1266
+GN++F Q + +QA ++ C++ G+ V + KA + PR+KVG E+V+K QN +
Sbjct: 357 MGNMKFKQRPREEQAEPDGQDEAERACNMYGIDVDQFLKALVSPRVKVGTEWVSKGQNVD 416
Query: 1267 QAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQIC 1446
Q +A+ A+AK Y R+F WLV + N +LD+ FIG+LDIAGFEIFD NSFEQ+
Sbjct: 417 QVHWAIGAMAKGLYARVFHWLVKKCNLTLDQKGIDRDYFIGVLDIAGFEIFDFNSFEQLW 476
Query: 1447 INYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEE 1626
IN+ NEKLQQ FN+ MF+LEQEEY REGI+W FIDFGLDLQ I+LIEKP+G++++LDEE
Sbjct: 477 INFVNEKLQQFFNHHMFVLEQEEYAREGIQWTFIDFGLDLQACIELIEKPLGIISMLDEE 536
Query: 1627 CLFPKANDKSFVEKLQKTH-NKHPKFIVP----DMRSKSHFAVVHYAGRVDYSADQWLMK 1791
C+ PKA D + +KL H KHP F P + ++HFA+ HYAG V Y+ WL K
Sbjct: 537 CIVPKATDMTLAQKLTDQHLGKHPNFEKPKPPKGKQGEAHFAMRHYAGTVRYNVLNWLEK 596
Query: 1792 NMDPLNENVVGLMQNS-TDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLH 1968
N DPLN+ VV +M+ S + + IW+D AA + G F TVS ++
Sbjct: 597 NKDPLNDTVVSVMKASKKNDLLVEIWQDYTTQEEAAAAAKAGGGRKGGKSGSFMTVSMMY 656
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
+E L KLMT L T PHF+RCIIPN +K+SG I++ LVL QL CNGVLEGIRICR+GFPN
Sbjct: 657 RESLNKLMTMLHKTHPHFIRCIIPNEKKQSGMIDAALVLNQLTCNGVLEGIRICRKGFPN 716
Query: 2149 RVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITAL----DIDTNLYRIGQSKVFFRTG 2316
R +F RY IL K+ D K ++ AL ++ +RIG +KVFF+ G
Sbjct: 717 RTQHPDFVQRYAILAAKE-AKSSDDMKTCAGAILQALINQKQLNDEQFRIGHTKVFFKAG 775
Query: 2317 VLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQ 2496
V+AH+E+ RD KL +I FQ+ R + + N ++ LR W
Sbjct: 776 VVAHIEDLRDDKLNQIITGFQSAIRWYTATADAGARRKQLNSYIILQRNIRSWCVLRTWD 835
Query: 2497 WWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQ 2676
W+ LF K++P L+ + +E+ +E + + K E + E+ ++ ER+ +
Sbjct: 836 WFLLFGKLRPQLKCGKMAEEMIKMAEEQKVLEAEAKKAESARKSQEEAYAKLSAERSKLL 895
Query: 2677 EQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVR 2856
E L+ SA +++ RL + QE+E +ND DRLS RRK + V
Sbjct: 896 EALELTQGGSAAIEEKLTRLNSARQEVEKSLNDANDRLSEHEEKNADLEKQRRKAQQEVE 955
Query: 2857 DXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTT 3036
+ +K + + L
Sbjct: 956 NLKKSIEAVDGNLAKSLEEKAAKENQIHSLQDEMNSQDETIGKINKEKKLLEENNRQLVD 1015
Query: 3037 QLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAE 3216
L E + + +G+LE L E+E+ + RE++ ++E E+ KRK+ EL+ +++ + E
Sbjct: 1016 DLQAEEAKQAQANRLRGKLEQTLDEMEEAVEREKRIRAETEKSKRKVEGELKGAQETIDE 1075
Query: 3217 KMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNA 3396
E + L K++ ++ R ++E A + +Q ++ I E+ +++E ER +
Sbjct: 1076 LSAIKLETDASLKKKEADIHALGVRIEDEQALANRLTRQSKENAQRIIEIEDELEHERQS 1135
Query: 3397 RNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK 3576
R+KA+ R E+ +L+++ + ++ + + QD +KD E+ +R +++ E +
Sbjct: 1136 RSKADRARAELQRELDELNERLDEQNKQLEIQQDNNKKKDSEIIKFRRDLDEKNMANEDQ 1195
Query: 3577 IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKK 3756
+ + K + Q+ L + ++ +K ++++EK++ +E D+ ++ SR + ++
Sbjct: 1196 MAMIRRKNNDQISALTNTLDALQKSKAKIEKEKGVLQKELDDINAQVDQETKSRVEQERL 1255
Query: 3757 RKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATA 3936
K +E + E+Q + E R ++ L R EE E A + R
Sbjct: 1256 AKQYEIQVAELQQKVDEQSRQIGEYTSTKGRLSNDNSDLARQVEELEIHLATINRAKTAF 1315
Query: 3937 XXXXXXXXXXXXXXTRLKIANINRARQLE---DEKNALLDE----KEEAEGLRAHLEKEI 4095
+ + LE D+ + LL+E K++ + + + EI
Sbjct: 1316 SSQLVEAKKAAEDELHERQEFHAACKNLEHELDQCHELLEEQINGKDDIQRQLSRINSEI 1375
Query: 4096 HAARQGAGEARRKAEESV-NQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQ 4272
+AR + E V +++LEEL++K + V LQ+ L ++ + ++K K+
Sbjct: 1376 -----SQWKARYEGEGLVGSEELEELKRKQMNRVMDLQEALSAAQNKVISLEKAKGKLLA 1430
Query: 4273 ELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLS 4452
E ED+ +++ EK+Q+ F+ + + + V + DA +++ R+ T V
Sbjct: 1431 ETEDARSDVDRHLTVIASLEKKQRAFDKIVDDWKRKVDDIQKEIDATTRDSRNTSTEVFK 1490
Query: 4453 LLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQ 4632
L + +D + E +E R + QE++D G+ E+ K+ R LE E ++++
Sbjct: 1491 LRSSMDNLSEQIETLRRENKIFSQEIRDINEQITQGGRTYQEVHKSVRRLEQEKDELQHA 1550
Query: 4633 MEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELEN 4812
++E E L+ E LRL++ Q ++SE ++ I K+ E E R+ + + ++ LE
Sbjct: 1551 LDEAEAALEAEESKVLRLQIEVQQIRSEIEKRIQEKEEEFENTRKNHQRALESIQASLET 1610
Query: 4813 EKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQA 4992
E + K+ +KK+E I +LE L+ AN+ + E Q + ++ ++
Sbjct: 1611 EAKSKAELARAKKKLETDINQLEIALDHANKANVDAQKNLKKLFDQVKELQGQVDDEQRR 1670
Query: 4993 KEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAK---GGGIS 5163
+E+I A+++ +E E L E + +KQ +
Sbjct: 1671 REEIRENYLAAEKRLAIALSESEDLAHRIEASDKHKKQLEIEQAELKSSNTELIGNNAAL 1730
Query: 5164 SEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEK 5343
S KR++E ++ + + + ++ RKA +++ ++ E+ + ++
Sbjct: 1731 SAMKRKVENEVQIARNELDEYLNELKASEERARKAAADADRLAEEVRQEQEHAVHVDRQR 1790
Query: 5344 QSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRL 5523
+SLE + ++ +AKI + E +A +E +V+ LE +L+ E + + + +
Sbjct: 1791 KSLELNAKELQAKIDDAERAMIQFGAKALAKVEDRVRSLEAELHSEQRRHQESIKGYTKQ 1850
Query: 5524 EKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQ 5694
E+R + Q E++K+A ++ +E +EK K R +RQ++EAE+ ++ +K R +Q
Sbjct: 1851 ERRARELQFQVEEDKKAFDRLQENVEKLQQKIRVQKRQIEEAEEVATQNLSKFRQIQ 1907
Score = 144 bits (364), Expect = 2e-32
Identities = 178/919 (19%), Positives = 376/919 (40%), Gaps = 34/919 (3%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLA---EKMGKVEELNNQLMKR 3261
LE + + E + + ++L + KLL LE ++ A EK+ ++ ++ K
Sbjct: 866 LEAEAKKAESARKSQEEAYAKLSAERSKLLEALELTQGGSAAIEEKLTRLNSARQEVEKS 925
Query: 3262 DEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQL 3441
+ +L+ ++E++A+ ++KQ R Q ++ L++ +E V L
Sbjct: 926 LNDANDRLSEHEEKNAD---LEKQRRKAQQEVENLKKSIEA--------------VDGNL 968
Query: 3442 EKVKGDVLDKVDEATMLQDLMSRKDE---EVNATKRAIE----------QIQHTMEGKIE 3582
K + K ++ LQD M+ +DE ++N K+ +E Q + + +
Sbjct: 969 AKSLEEKAAKENQIHSLQDEMNSQDETIGKINKEKKLLEENNRQLVDDLQAEEAKQAQAN 1028
Query: 3583 EQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRK 3762
+ K + ++E+ + +E+ K+ R++ EK + + + E + I L A + + D K
Sbjct: 1029 RLRGKLEQTLDEMEEAVEREKRIRAETEKSKRKVEGELKGAQETIDELSAIKLETDASLK 1088
Query: 3763 IHEAHLMEIQANLAESDEHKRTLIDQLERS-------RDELDHLNRVREEEEHAFANMQR 3921
EA + + + + L Q + + DEL+H + R + + A A +QR
Sbjct: 1089 KKEADIHALGVRIEDEQALANRLTRQSKENAQRIIEIEDELEHERQSRSKADRARAELQR 1148
Query: 3922 RLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEK---- 4089
L DE N LDE+ + ++ K
Sbjct: 1149 EL--------------------------------DELNERLDEQNKQLEIQQDNNKKKDS 1176
Query: 4090 EIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQ 4269
EI R+ E E+ Q+ +R+KN + L L+ + +K +I + K +Q
Sbjct: 1177 EIIKFRRDLDEKNMANED----QMAMIRRKNNDQISALTNTLDALQKSKAKIEKEKGVLQ 1232
Query: 4270 QELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL 4449
+EL+D + +++ S + E+ K++E Q+AE +Q+ + ++ E + R+
Sbjct: 1233 KELDDINAQVDQETKSRVEQERLAKQYEIQVAE----LQQKVDEQSRQIGEYTSTKGRLS 1288
Query: 4450 S----LLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELN 4617
+ L +V+ ++ HL +R + + +L ++ +D E A ++LE EL+
Sbjct: 1289 NDNSDLARQVEELEIHLATINRAKTAFSSQLVEAKKAAEDELHERQEFHAACKNLEHELD 1348
Query: 4618 DMRVQMEEL---EDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIR 4788
+EE +D++Q + +R+ E++ + E + + ++ E EE +R + ++
Sbjct: 1349 QCHELLEEQINGKDDIQ-RQLSRINSEISQWKARYEGEGLVGSE--ELEELKRKQMNRVM 1405
Query: 4789 DLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQI 4968
DL+ L S A + +E G+L + E A + + +
Sbjct: 1406 DLQEAL-------SAAQNKVISLEKAKGKLLAETEDARSDVDRHLTVIASLEKKQRAFDK 1458
Query: 4969 ECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAK 5148
++ ++ +DI + R R E +LR + + L + + +
Sbjct: 1459 IVDDWKRKVDDIQKEIDATTRDSRNTSTEVFKLRSSMDNLSEQIETLR-----------R 1507
Query: 5149 GGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQK 5328
I S+E R + +I Q + ++ + Q L++ L E + +
Sbjct: 1508 ENKIFSQEIRDINEQITQGGRTYQEVHKSVRRLEQEKDELQHALDEAEAALEAEESKVLR 1567
Query: 5329 TEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANR 5508
+ E Q + + + +I E E ++ + ALE+ ++ L E + K R
Sbjct: 1568 LQIEVQQIRS---EIEKRIQEKEEEFENTRKNHQRALES----IQASLETEAKSKAELAR 1620
Query: 5509 AARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRN 5688
A ++LE +N + +AN A++ L+K + + L+ Q+D+ + R +
Sbjct: 1621 AKKKLETDINQLEIALDHANKANVDAQKNLKKLFDQVKELQGQVDDEQRRREEIRENYLA 1680
Query: 5689 VQREADDLLDANEQLTREL 5745
++ L +E L +
Sbjct: 1681 AEKRLAIALSESEDLAHRI 1699
Score = 36.6 bits (83), Expect = 7.6
Identities = 28/135 (20%), Positives = 61/135 (44%), Gaps = 6/135 (4%)
Frame = +1
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEG------QEK 5493
E K + E+ + +AK E +Q A A+++A +K+ LE +G ++
Sbjct: 855 EMIKMAEEQKVLEAEAKKAESARKSQEEAYAKLSAERSKL--LEALELTQGGSAAIEEKL 912
Query: 5494 TAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRER 5673
T N A + +EK LND + + + N ++ K+ + NL++ ++ + +++
Sbjct: 913 TRLNSARQEVEKSLNDANDRLSEHEEKNADLEKQRRKAQQEVENLKKSIEAVDGNLAKSL 972
Query: 5674 TKHRNVQREADDLLD 5718
+ + + L D
Sbjct: 973 EEKAAKENQIHSLQD 987
>gi|27529750|dbj|BAA76844.2| KIAA1000 protein [Homo sapiens]
Length = 1956
Score = 1013 bits (2618), Expect = 0.0
Identities = 624/1903 (32%), Positives = 1012/1903 (52%), Gaps = 19/1903 (0%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETND-EVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMS 252
+K CW+PD ++ +K +D V+VE D ++I D +Q+ NPP+F+ IEDM+
Sbjct: 61 KKKCWIPDGENAYIEAEVKGSEDDGTVIVETAD-GESLSIKEDKIQQMNPPEFEMIEDMA 119
Query: 253 ELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMP 432
LT+LNEASVLH LK RY +IYTYSGLFCV INPYK LP+Y ++++ +KGK+R E P
Sbjct: 120 MLTHLNEASVLHTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAP 179
Query: 433 PHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAA 612
PHIFA+A+ A++ ML RE+QSIL TGESGAGKT N+K +IQY A +A +
Sbjct: 180 PHIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIES------- 232
Query: 613 QQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYIS 792
R G LE Q++QAN ILEAFGN+KT++NDNSSRFGKFIR++F G +S
Sbjct: 233 ----------RKKQGALEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLS 282
Query: 793 GANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGI 966
+I+ YLLEKSRV+ Q ER++HIFYQIL G KE + LL + ++ F +
Sbjct: 283 SVDIDIYLLEKSRVIFQQAGERNYHIFYQILSG--QKELHDLLLVSANPSDFHFCSCGAV 340
Query: 967 TLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDD 1146
T+ ++DD +E +T +M I+GF DE ++ A++ GN++F Q+ + +Q
Sbjct: 341 TVESLDDAEELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGT 400
Query: 1147 RVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKW 1326
K L+G+ EL K + PRIKVG E+V + Q EQ AV A++K+ YER+FKW
Sbjct: 401 ENADKAAFLMGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVTCAVGALSKSMYERMFKW 460
Query: 1327 LVTRINKSLD-RTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFIL 1503
LV RIN++LD + RQ FIGILDI GFEI + NS EQ+CIN+TNEKLQQ FN MF+L
Sbjct: 461 LVARINRALDAKLSRQ--FFIGILDITGFEILEYNSLEQLCINFTNEKLQQFFNWYMFVL 518
Query: 1504 EQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH 1683
EQEEY++E IEW I FGLDLQ IDLIEKPMG+L++L+EEC+FPKA D +F KL H
Sbjct: 519 EQEEYKKESIEWVSIGFGLDLQACIDLIEKPMGILSILEEECMFPKATDLTFKTKLFDNH 578
Query: 1684 ---NKHPKFIVPDMRS-KSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPF 1851
+ H + PD + ++HF +VHYAG V Y+ WL KN D LNE VV + Q S++
Sbjct: 579 FGKSVHLQKPKPDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRL 638
Query: 1852 VAGIWKDAEFAGICAAEMNETAFGMRSRK--GMFRTVSQLHKEQLTKLMTTLRNTSPHFV 2025
+A ++++ + + FG + RK F+TV+ LHKE L KLMT L++T+PHFV
Sbjct: 639 LASLFEN------YMSTDSAIPFGEKKRKKGASFQTVASLHKENLNKLMTNLKSTAPHFV 692
Query: 2026 RCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVI 2205
RCI PN K G ++ LVL+QLRCNGVLEG RICR+GFPNR+ + +F+ RY IL P
Sbjct: 693 RCINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYCILNPRTF 752
Query: 2206 PKN-FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQA 2382
PK+ F+ +++ +++ +L+ID YR G +KVFF+ G L LE RD +L+ + FQA
Sbjct: 753 PKSKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFTLFQA 812
Query: 2383 QCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIR 2562
+ +G L R + N A++ ++NW W RLF K+KPL++ + +E+
Sbjct: 813 RAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVKSSEVGEEVA 872
Query: 2563 AKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQT 2742
+E ++ L K E E + K + E+ + QLQ E E A +++ L
Sbjct: 873 GLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIK 932
Query: 2743 RNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTN 2922
+LE V ++ +R+ RK + + +K
Sbjct: 933 SKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRT 992
Query: 2923 VDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQ 3102
+ + L EE+ KA +LE Q
Sbjct: 993 TEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQ 1052
Query: 3103 LHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQ 3282
+ ELE L +ER+ + E+ KL L+ +++ + L +L K++ EL
Sbjct: 1053 VDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQM 1112
Query: 3283 LTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDV 3462
++ + E V +QK ++++QT I +L+E +E ER R K E R ++ L + +
Sbjct: 1113 NSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADL-NER 1171
Query: 3463 LDKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQ 3639
L++V +++ Q ++ +++ ++ R +E+ E K + + + EL Q+E
Sbjct: 1172 LEEVGGSSLAQLEITKKQETKIQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVEN 1231
Query: 3640 HKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEH 3819
++ + +LEK ++ E D+ + + ++A+ +K ++E L E A L + +
Sbjct: 1232 LQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQL 1291
Query: 3820 KRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIAN 3999
L Q + E R EE+E + R + T+ + A
Sbjct: 1292 ANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSAL 1351
Query: 4000 INRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKK 4179
+ ++ + + + L ++ EE + ++A L + + + R K E +V Q+ E+L
Sbjct: 1352 AHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDA 1411
Query: 4180 NLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKF 4350
LQ+ E VA R + +++ ++Q EL D+ +L VR++ +++Q +
Sbjct: 1412 KKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQS 1471
Query: 4351 ESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQEL 4530
+A+ + +++ DA +E++ T +L L N + E R ++LQ+E+
Sbjct: 1472 GKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEI 1531
Query: 4531 QDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALK 4710
+ + + KN+ E+EK K+ +E E +++V +EE E L+ E L ++ K
Sbjct: 1532 SNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAK 1591
Query: 4711 SESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
+E +R +S KD E E RR I L++ L++E + + +KK+E + E+E QL
Sbjct: 1592 AELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQL 1651
Query: 4891 EVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLR 5070
ANR E + Q++ +++ Q D+ + A+R+ +++E E LR
Sbjct: 1652 SCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLR 1711
Query: 5071 EANE----GLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNC 5238
E G + ++ + + S +K++LEA +A+ C
Sbjct: 1712 SLQEQTERGRRLSEEELLEATERINLFYTQNTSLLS-QKKKLEADVARMQKEAEEVVQEC 1770
Query: 5239 ELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRA 5418
+ A +K +KA ++ ++ +L ++ E ++++E++ D + ++ E E A +
Sbjct: 1771 QNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGS 1830
Query: 5419 RAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELL 5598
R Q+ LE++V+ LE +L E + A R ARRLE+ + + T Q E++K+ + + +
Sbjct: 1831 RKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQM 1890
Query: 5599 EKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANE 5727
+K LK +N ++Q++ AE + ++ +K++ Q E +++ + E
Sbjct: 1891 DKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAE 1933
Score = 136 bits (342), Expect = 7e-30
Identities = 180/846 (21%), Positives = 369/846 (43%), Gaps = 34/846 (4%)
Frame = +1
Query: 3028 LTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDH 3207
L TQ+ D +E+ + + ++E + +L QDL LE+ LA+LE +K
Sbjct: 1133 LQTQIKDLKEKLEAERTTRAKMERERADLTQDL---ADLNERLEEVGGSSLAQLEITKKQ 1189
Query: 3208 ----------LAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANV-TLMQKQMRDMQTT 3354
+ E E + L KR + +L E V ++K D+Q
Sbjct: 1190 ETKIQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLE 1249
Query: 3355 IDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATML-QDLMSRKDE---E 3522
+D+L +E A+ AE ++ E+ + K+D+ T L DL ++K + E
Sbjct: 1250 VDDLLTRVEQMTRAKANAE----KLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSE 1305
Query: 3523 VNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRS----QLEKQQNQAD- 3687
R +E+ + + ++ +K+ F+RQ+E+L Q+E+ K +S L+K Q D
Sbjct: 1306 SGEFLRRLEE-KEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDL 1364
Query: 3688 -QERADMAQEI-----ALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLER 3849
+E+ + QE+ L A++ + R +E ++++ +L ++ K+ L +L+
Sbjct: 1365 LREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDL---EDAKKELAIRLQE 1421
Query: 3850 SRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDE 4029
+ + + N E A +Q L A RL + + L D
Sbjct: 1422 AAEAMGVANARNASLERARHQLQLELGDA---LSDLGKVRSAAARLDQKQLQSGKALADW 1478
Query: 4030 KNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN---LRDVEH 4200
K + EE++ L +KE+ A + + EES+ Q E LR++N ++ +
Sbjct: 1479 K----QKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQ-ETLRRENKNLQEEISN 1533
Query: 4201 LQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVA 4380
L Q+ E + + KK I++E + + LE + +E + F+ ++ E +
Sbjct: 1534 LTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAE 1593
Query: 4381 VQKALLDRDAMSQELRDRETRVL-SLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDD 4557
+++ L ++D + R ++ + SL + +D + E R+++ ++++L +
Sbjct: 1594 LERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSC 1653
Query: 4558 FGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVT---NQALKSESDRA 4728
+ V E K+ L+ ++ D+++Q L+D+ Q+ D + ++ V N L+SE +
Sbjct: 1654 ANRQVSEATKSLGQLQIQIKDLQMQ---LDDSTQLNSDLKEQVAVAERRNSLLQSELEDL 1710
Query: 4729 ISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRL 4908
S ++ + E RR +++ + + + +S +KK+E + ++++ A +
Sbjct: 1711 RSLQE-QTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKE---AEEV 1766
Query: 4909 KEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANE-G 5085
+E E EE ++ ++ IA L R + + + +++L EA +
Sbjct: 1767 VQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMA 1826
Query: 5086 LMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRK 5265
LM +RKQ R G + E +R EA+ + + DK+
Sbjct: 1827 LMGSRKQ---IQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNL 1883
Query: 5266 AQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEA 5445
+++Q + L ++ Q AE Q+ + ++ YK + EL + + RA++A E+
Sbjct: 1884 SRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSK-YKKQQHELN---EVKERAEVA--ES 1937
Query: 5446 KVQYLE 5463
+V L+
Sbjct: 1938 QVNKLK 1943
Score = 66.2 bits (160), Expect = 9e-09
Identities = 80/413 (19%), Positives = 170/413 (40%), Gaps = 14/413 (3%)
Frame = +1
Query: 4555 DFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDR-AI 4731
+ G+ V L++ L+ L Q EEL+ A+ L E + L+ ++++ +
Sbjct: 866 EVGEEVAGLKEECAQLQKALEKSEFQREELK-----AKQVSLTQEKNDLILQLQAEQETL 920
Query: 4732 SNKDVEAE---EKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVAN 4902
+N + + E + + L ++++L +E E+ S + +K+E++ EL+++++
Sbjct: 921 ANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDL- 979
Query: 4903 RLKEEYXXXXXXXXXXXXEYQIE--CEEARQAKEDIAALLREA-------DRKFRAVEAE 5055
E E++++ EE EDI+ L R A + + E
Sbjct: 980 ----ETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHME 1035
Query: 5056 REQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSN 5235
E+L ++ ++ +Q R K E +LE + +S+
Sbjct: 1036 EEKLSSLSKANLKLEQQVDELEGALEQER-KARMNCERELHKLEGNLKLNRESMENLESS 1094
Query: 5236 CELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSR 5415
++ RK +++L Q+ + + E+ L + + + L+ +D K K+ E E +++
Sbjct: 1095 QRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKL-EAERTTRAK 1153
Query: 5416 ARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKEL 5595
+ A L + L ++L G A ++ E ++ + E+ E
Sbjct: 1154 MERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKIQKLHRDMEEATLHFETTSAS 1213
Query: 5596 LEKSNLKN-RNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
L+K + + L Q++ + + ++Q E DDLL EQ+TR N
Sbjct: 1214 LKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKAN 1266
Score = 54.3 bits (129), Expect = 4e-05
Identities = 67/340 (19%), Positives = 123/340 (35%), Gaps = 8/340 (2%)
Frame = +1
Query: 4738 KDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEE 4917
K E E+ GL ++ L+ LE K E Q EL+ + + K +
Sbjct: 863 KSSEVGEEVAGLKEECAQLQKALE--------------KSEFQREELKAKQVSLTQEKND 908
Query: 4918 YXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQL----REANEG 5085
+ +CE ++K + A ++E + E +L R+ +
Sbjct: 909 LILQLQAEQETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDE 968
Query: 5086 LMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRK 5265
+ +K+ S +EKR E K+ + +
Sbjct: 969 CFELKKEIDDLETMLVK--------SEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKV 1020
Query: 5266 AQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEA 5445
Q +Q DL ME E + SL ++N + ++ ELE + +A+M E
Sbjct: 1021 VQEAHQQTLDDLHME-------EEKLSSLSKANLKLEQQVDELEGALEQERKARMNC-ER 1072
Query: 5446 KVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRN 5625
++ LE L + + + R L + L + E K L+ + +
Sbjct: 1073 ELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKE 1132
Query: 5626 LRRQLDEAEDEMSRERTKHRNVQRE----ADDLLDANEQL 5733
L+ Q+ + ++++ ERT ++RE DL D NE+L
Sbjct: 1133 LQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERL 1172
>gi|127751|sp|P02567|MYSD_CAEEL Myosin heavy chain D (MHC D)
gi|6786|emb|CAA30854.1| myosin 1 [Caenorhabditis elegans]
Length = 1938
Score = 1013 bits (2618), Expect = 0.0
Identities = 621/1917 (32%), Positives = 1012/1917 (52%), Gaps = 23/1917 (1%)
Frame = +1
Query: 13 QYLQVQRAA-VADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVT 189
QYL+ R +AD + + +K W+PD EG++ G IK V + + VT
Sbjct: 12 QYLKRSREQQLADQSR--PYDSKKNVWIPDAEEGYIEGVIKGPGPKADTVIVTAGGKDVT 69
Query: 190 ISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKK 369
+ +D VQ+ NPPKF+K EDMS LT+LN+ASVL NL+ RY + LIYTYSGLFCVVINPYK+
Sbjct: 70 LKKDIVQEVNPPKFEKTEDMSNLTFLNDASVLWNLRSRYAAMLIYTYSGLFCVVINPYKR 129
Query: 370 LPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKK 549
LPIY++ + F GK+R EMPPH+FA++D AYR MLQ+ E+QS+L TGESGAGKTENTKK
Sbjct: 130 LPIYTDSVARMFMGKRRTEMPPHLFAVSDQAYRYMLQDHENQSMLITGESGAGKTENTKK 189
Query: 550 VIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKN 729
VI Y A V GA++ +L ++ LE Q++Q NP+LEAFGN+KTV+N
Sbjct: 190 VICYFATV-GASQKAALKEGEKEVT------------LEDQIVQTNPVLEAFGNAKTVRN 236
Query: 730 DNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEK 909
+NSSRFGKFIRI+F+ G ++ +IE YLLEKSRV+RQA ER +HIFYQI + +
Sbjct: 237 NNSSRFGKFIRIHFNKHGTLASCDIEHYLLEKSRVIRQAPGERCYHIFYQIYSDFKPQLR 296
Query: 910 SEYLLEG-VDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLL 1086
E LL + NY F+ + + +DD +EF T + ++ F+ E R++SA +
Sbjct: 297 DELLLNHPISNYWFVAQAELLIDGIDDTEEFQLTDEAFDVLKFSPTEKMDCYRLMSAHMH 356
Query: 1087 LGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQE 1266
+GN++F Q + +QA ++ C++ G+ V++ KA + PR+KVG E+V+K QN +
Sbjct: 357 MGNMKFKQRPREEQAEPDGQVEAERACNMYGIDVVQFLKALVSPRVKVGTEWVSKGQNVD 416
Query: 1267 QAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQIC 1446
Q +A+ A+AK Y R+F WLV + N +LD+ FIG+LDIAGFEIFD NSFEQ+
Sbjct: 417 QVHWAIGAMAKGLYARVFHWLVKKCNLTLDQKGIDRDYFIGVLDIAGFEIFDFNSFEQLW 476
Query: 1447 INYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEE 1626
IN+ NEKLQQ FN+ MF+LEQEEY REGI+W FIDFGLDLQ I+LIEKP+G++++LDEE
Sbjct: 477 INFVNEKLQQFFNHHMFVLEQEEYAREGIQWTFIDFGLDLQACIELIEKPLGIISMLDEE 536
Query: 1627 CLFPKANDKSFVEKLQKTH-NKHPKFIVP----DMRSKSHFAVVHYAGRVDYSADQWLMK 1791
C+ PKA D + +KL H KHP F P + ++H A+ HYAG V Y+ WL K
Sbjct: 537 CIVPKATDMTLAQKLTDQHLGKHPNFEKPKPPKGKQGEAHLAMRHYAGTVRYNVLNWLEK 596
Query: 1792 NMDPLNENVVGLMQNS-TDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLH 1968
N DPLN+ VV +M+ S + + IW+D AA + G F TVS ++
Sbjct: 597 NKDPLNDTVVSVMKASKKNDLLVEIWQDYTTQEEAAAAAKAGGGRKGGKSGSFMTVSMMY 656
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
+E L KLMT L T PHF+RCIIP +K+SG I++ LVL QL CNGVLEGIRICR+GFPN
Sbjct: 657 RESLNKLMTMLHKTHPHFIRCIIPIEKKQSGMIDAALVLNQLTCNGVLEGIRICRKGFPN 716
Query: 2149 RVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITAL----DIDTNLYRIGQSKVFFRTG 2316
R +F RY IL K+ D K ++ AL ++ +RIG +KVFF+ G
Sbjct: 717 RTQHPDFVQRYAILAAKE-AKSSDDMKTCAGAILQALINQKQLNDEQFRIGHTKVFFKAG 775
Query: 2317 VLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQ 2496
V+AH+E+ RD KL +I FQ+ R + + N ++ LR W
Sbjct: 776 VVAHIEDLRDDKLNQIITGFQSAIRWYTATADAGARRKQLNSYIILQRNIRSWCVLRTWD 835
Query: 2497 WWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQ 2676
W+ LF K++P L+ + +E+ +E + + K E + E+ ++ ER+ +
Sbjct: 836 WFLLFGKLRPQLKCGKMAEEMIKMAEEQKVLEAEAKKAESARKSQEEAYAKLSAERSKLL 895
Query: 2677 EQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVR 2856
E L+ SA +++ RL + QE+E +ND DRLS RRK + V
Sbjct: 896 EALELTQGGSAAIEEKLTRLNSARQEVEKSLNDANDRLSEHEEKNADLEKQRRKAQQEVE 955
Query: 2857 DXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTT 3036
+ +K + + L
Sbjct: 956 NLKKSIEAVDGNLAKSLEEKAAKENQIHSLQDEMNSQDETIGKINKEKKLLEENNRQLVD 1015
Query: 3037 QLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAE 3216
L E + + +G+LE L E+E+ + RE++ ++E E+ KRK+ EL+ +++ + E
Sbjct: 1016 DLQAEEAKQAQANRLRGKLEQTLDEMEEAVEREKRIRAETEKSKRKVEGELKGAQETIDE 1075
Query: 3217 KMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNA 3396
E + L K++ ++ R ++E A + +Q ++ I E+ +++E ER +
Sbjct: 1076 LSAIKLETDASLKKKEADIHALGVRIEDEQALANRLTRQSKENAQRIIEIEDELEHERQS 1135
Query: 3397 RNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK 3576
R+KA+ R E+ +L+++ + ++ + + QD +KD E+ +R +++ E +
Sbjct: 1136 RSKADRARAELQRELDELNERLDEQNKQLEIQQDNNKKKDSEIIKFRRDLDEKNMANEDQ 1195
Query: 3577 IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKK 3756
+ + K + Q+ L + ++ +K ++++EK++ +E D+ ++ SR + ++
Sbjct: 1196 MAMIRRKNNDQISALTNTLDALQKSKAKIEKEKGVLQKELDDINAQVDQETKSRVEQERL 1255
Query: 3757 RKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATA 3936
K +E + E+Q + E R ++ L R EE E A + R
Sbjct: 1256 AKQYEIQVAELQQKVDEQSRQIGEYTSTKGRLSNDNSDLARQVEELEIHLATINRAKTAF 1315
Query: 3937 XXXXXXXXXXXXXXTRLKIANINRARQLE---DEKNALLDE----KEEAEGLRAHLEKEI 4095
+ + LE D+ + LL+E K++ + + + EI
Sbjct: 1316 SSQLVEAKKAAEDELHERQEFHAACKNLEHELDQCHELLEEQINGKDDIQRQLSRINSEI 1375
Query: 4096 HAARQGAGEARRKAEESV-NQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQ 4272
+AR + E V +++LEEL++K + V LQ+ L ++ + ++K K+
Sbjct: 1376 -----SQWKARYEGEGLVGSEELEELKRKQMNRVMDLQEALSAAQNKVISLEKAKGKLLA 1430
Query: 4273 ELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLS 4452
E ED+ +++ EK+Q+ F+ + + + V + DA +++ R+ T V
Sbjct: 1431 ETEDARSDVDRHLTVIASLEKKQRAFDKIVDDWKRKVDDIQKEIDATTRDSRNTSTEVFK 1490
Query: 4453 LLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQ 4632
L + +D + E +E R + QE++D G+ E+ K+ R LE E ++++
Sbjct: 1491 LRSSMDNLSEQIETLRRENKIFSQEIRDINEQITQGGRTYQEVHKSVRRLEQEKDELQHA 1550
Query: 4633 MEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELEN 4812
++E E L+ E LRL++ Q ++SE ++ I K+ E E R+ + + ++ LE
Sbjct: 1551 LDEAEAALEAEESKVLRLQIEVQQIRSEIEKRIQEKEEEFENTRKNHQRALESIQASLET 1610
Query: 4813 EKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQA 4992
E + K+ +KK+E I +LE L+ AN+ + E Q + ++ ++
Sbjct: 1611 EAKSKAELARAKKKLETDINQLEIALDHANKANVDAQKNLKKLFDQVKELQGQVDDEQRR 1670
Query: 4993 KEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAK---GGGIS 5163
+E+I A+++ +E E L E + +KQ +
Sbjct: 1671 REEIRENYLAAEKRLAIALSESEDLAHRIEASDKHKKQLEIEQAELKSSNTELIGNNAAL 1730
Query: 5164 SEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEK 5343
S KR++E ++ + + + ++ RKA +++ ++ E+ + ++
Sbjct: 1731 SAMKRKVENEVQIARNELDEYLNELKASEERARKAAADADRLAEEVRQEQEHAVHVDRQR 1790
Query: 5344 QSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRL 5523
+SLE + ++ +AKI + E +A +E +V+ LE +L+ E + + + +
Sbjct: 1791 KSLELNAKELQAKIDDAERAMIQFGAKALAKVEDRVRSLEAELHSEQRRHQESIKGYTKQ 1850
Query: 5524 EKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQ 5694
E+R + Q E++K+A ++ +E +EK K R +RQ++EAE+ ++ +K R +Q
Sbjct: 1851 ERRARELQFQVEEDKKAFDRLQENVEKLQQKIRVQKRQIEEAEEVATQNLSKFRQIQ 1907
Score = 144 bits (364), Expect = 2e-32
Identities = 178/919 (19%), Positives = 376/919 (40%), Gaps = 34/919 (3%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLA---EKMGKVEELNNQLMKR 3261
LE + + E + + ++L + KLL LE ++ A EK+ ++ ++ K
Sbjct: 866 LEAEAKKAESARKSQEEAYAKLSAERSKLLEALELTQGGSAAIEEKLTRLNSARQEVEKS 925
Query: 3262 DEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQL 3441
+ +L+ ++E++A+ ++KQ R Q ++ L++ +E V L
Sbjct: 926 LNDANDRLSEHEEKNAD---LEKQRRKAQQEVENLKKSIEA--------------VDGNL 968
Query: 3442 EKVKGDVLDKVDEATMLQDLMSRKDE---EVNATKRAIE----------QIQHTMEGKIE 3582
K + K ++ LQD M+ +DE ++N K+ +E Q + + +
Sbjct: 969 AKSLEEKAAKENQIHSLQDEMNSQDETIGKINKEKKLLEENNRQLVDDLQAEEAKQAQAN 1028
Query: 3583 EQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRK 3762
+ K + ++E+ + +E+ K+ R++ EK + + + E + I L A + + D K
Sbjct: 1029 RLRGKLEQTLDEMEEAVEREKRIRAETEKSKRKVEGELKGAQETIDELSAIKLETDASLK 1088
Query: 3763 IHEAHLMEIQANLAESDEHKRTLIDQLERS-------RDELDHLNRVREEEEHAFANMQR 3921
EA + + + + L Q + + DEL+H + R + + A A +QR
Sbjct: 1089 KKEADIHALGVRIEDEQALANRLTRQSKENAQRIIEIEDELEHERQSRSKADRARAELQR 1148
Query: 3922 RLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEK---- 4089
L DE N LDE+ + ++ K
Sbjct: 1149 EL--------------------------------DELNERLDEQNKQLEIQQDNNKKKDS 1176
Query: 4090 EIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQ 4269
EI R+ E E+ Q+ +R+KN + L L+ + +K +I + K +Q
Sbjct: 1177 EIIKFRRDLDEKNMANED----QMAMIRRKNNDQISALTNTLDALQKSKAKIEKEKGVLQ 1232
Query: 4270 QELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL 4449
+EL+D + +++ S + E+ K++E Q+AE +Q+ + ++ E + R+
Sbjct: 1233 KELDDINAQVDQETKSRVEQERLAKQYEIQVAE----LQQKVDEQSRQIGEYTSTKGRLS 1288
Query: 4450 S----LLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELN 4617
+ L +V+ ++ HL +R + + +L ++ +D E A ++LE EL+
Sbjct: 1289 NDNSDLARQVEELEIHLATINRAKTAFSSQLVEAKKAAEDELHERQEFHAACKNLEHELD 1348
Query: 4618 DMRVQMEEL---EDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIR 4788
+EE +D++Q + +R+ E++ + E + + ++ E EE +R + ++
Sbjct: 1349 QCHELLEEQINGKDDIQ-RQLSRINSEISQWKARYEGEGLVGSE--ELEELKRKQMNRVM 1405
Query: 4789 DLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQI 4968
DL+ L S A + +E G+L + E A + + +
Sbjct: 1406 DLQEAL-------SAAQNKVISLEKAKGKLLAETEDARSDVDRHLTVIASLEKKQRAFDK 1458
Query: 4969 ECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAK 5148
++ ++ +DI + R R E +LR + + L + + +
Sbjct: 1459 IVDDWKRKVDDIQKEIDATTRDSRNTSTEVFKLRSSMDNLSEQIETLR-----------R 1507
Query: 5149 GGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQK 5328
I S+E R + +I Q + ++ + Q L++ L E + +
Sbjct: 1508 ENKIFSQEIRDINEQITQGGRTYQEVHKSVRRLEQEKDELQHALDEAEAALEAEESKVLR 1567
Query: 5329 TEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANR 5508
+ E Q + + + +I E E ++ + ALE+ ++ L E + K R
Sbjct: 1568 LQIEVQQIRS---EIEKRIQEKEEEFENTRKNHQRALES----IQASLETEAKSKAELAR 1620
Query: 5509 AARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRN 5688
A ++LE +N + +AN A++ L+K + + L+ Q+D+ + R +
Sbjct: 1621 AKKKLETDINQLEIALDHANKANVDAQKNLKKLFDQVKELQGQVDDEQRRREEIRENYLA 1680
Query: 5689 VQREADDLLDANEQLTREL 5745
++ L +E L +
Sbjct: 1681 AEKRLAIALSESEDLAHRI 1699
Score = 36.6 bits (83), Expect = 7.6
Identities = 28/135 (20%), Positives = 61/135 (44%), Gaps = 6/135 (4%)
Frame = +1
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEG------QEK 5493
E K + E+ + +AK E +Q A A+++A +K+ LE +G ++
Sbjct: 855 EMIKMAEEQKVLEAEAKKAESARKSQEEAYAKLSAERSKL--LEALELTQGGSAAIEEKL 912
Query: 5494 TAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRER 5673
T N A + +EK LND + + + N ++ K+ + NL++ ++ + +++
Sbjct: 913 TRLNSARQEVEKSLNDANDRLSEHEEKNADLEKQRRKAQQEVENLKKSIEAVDGNLAKSL 972
Query: 5674 TKHRNVQREADDLLD 5718
+ + + L D
Sbjct: 973 EEKAAKENQIHSLQD 987
>gi|39588011|emb|CAE57242.1| Hypothetical protein CBG00120
[Caenorhabditis briggsae]
Length = 1945
Score = 1012 bits (2617), Expect = 0.0
Identities = 629/1937 (32%), Positives = 1013/1937 (51%), Gaps = 31/1937 (1%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL+ R + + + A+ +K W+PD EG++ G I + + V V + T+
Sbjct: 10 KYLRRSREQMLEDQS-RAYDSKKNVWIPDAEEGYIEGIITKTAGENVTVS-TGPGVEKTV 67
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
+D VQ+ NPPKF+K EDMS LT+LN+ASVL+NL+ RY + LIYTYSGLFCVVINPYK+L
Sbjct: 68 KKDIVQEMNPPKFEKTEDMSNLTFLNDASVLYNLRARYAAMLIYTYSGLFCVVINPYKRL 127
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIY++ + F GK+R EMPPH+FA++D AYR+MLQ E+QS+L TGESGAGKTENTKKV
Sbjct: 128 PIYTDSVARMFMGKRRTEMPPHLFAVSDEAYRNMLQNHENQSMLITGESGAGKTENTKKV 187
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
I Y A V GA + ++ A + K V LE Q++Q NP+LEAFGN+KTV+N+
Sbjct: 188 ISYFAAV-GAAQQETFGAKKAEEDKDKKKVT-----LEDQIVQTNPVLEAFGNAKTVRNN 241
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRI+F G ++ +IE YLLEKSRV+RQA ER +HIFYQ+ K
Sbjct: 242 NSSRFGKFIRIHFSKQGRVASCDIEHYLLEKSRVIRQAPGERCYHIFYQVFSDFVPTLKK 301
Query: 913 EYLL-EGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLL 1089
+ LL + V +Y F+ + + V+D +E T + I+ F+ E R+V+A++ +
Sbjct: 302 DLLLNKPVKDYWFIAQAELQIDGVNDKEEHQLTDEAFDILKFSPTEKMECYRLVAAMMHM 361
Query: 1090 GNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQ 1269
GN++F Q + +QA ++ G+ E KA RPR+KVG E+VNK QN EQ
Sbjct: 362 GNMKFKQRPREEQAEPDGTDDAERAAKCFGIDPEEFLKALTRPRVKVGNEWVNKGQNIEQ 421
Query: 1270 AEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICI 1449
+AV A+AK Y R+F WLV + N++LD+ FIG+LDIAGFEIFD NSFEQ+ I
Sbjct: 422 VNWAVGAMAKGLYSRIFNWLVKKCNQTLDQKGISRDYFIGVLDIAGFEIFDFNSFEQLWI 481
Query: 1450 NYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEEC 1629
N+ NEKLQQ FN+ MF+LEQEEY REGI+W FIDFGLDLQ I+LIEKP+G++A+LDEEC
Sbjct: 482 NFVNEKLQQFFNHHMFVLEQEEYAREGIQWTFIDFGLDLQACIELIEKPLGIIAMLDEEC 541
Query: 1630 LFPKANDKSFVEKLQKTH-NKHPKFIVP----DMRSKSHFAVVHYAGRVDYSADQWLMKN 1794
+ PKA D + +KL H KHP F P ++++HFA+ HYAG V Y+ WL KN
Sbjct: 542 IVPKATDATLAQKLIDQHLGKHPNFEKPKPPKGKQAEAHFAMRHYAGTVRYNVMNWLEKN 601
Query: 1795 MDPLNENVVGLMQNSTD-PFVAGIWKDAEFAGICAAEMNETAFG--MRSRKGMFRTVSQL 1965
DPLN+ VV +M+ S + + +W+D AA ++ G + + G F TVS L
Sbjct: 602 KDPLNDTVVTVMKASKEHALIVEVWQDYTTQEEAAAAASKGGPGGKKKGKSGSFMTVSML 661
Query: 1966 HKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFP 2145
++E L KLMT L T PHF+RCIIPN +K+SG I++ LVL QL CNGVLEGIRICR+GFP
Sbjct: 662 YRESLNKLMTMLNATHPHFIRCIIPNEKKQSGMIDAGLVLNQLTCNGVLEGIRICRKGFP 721
Query: 2146 NRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITAL----DIDTNLYRIGQSKVFFRT 2313
NR +F RY +L D D K+ M+ L ++ + +R+G +KVFF+
Sbjct: 722 NRTLHPDFVQRYALLAADESIIGKTDAKKGSALMLARLVKEKKLEEDNFRVGLTKVFFKA 781
Query: 2314 GVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNW 2493
G++AHLE+ RD +L LI QAQ R F N ++ +LR W
Sbjct: 782 GIVAHLEDLRDSRLAQLITGLQAQIRWFYQLIERKRRVEKITALKVIQRNVRSWAELRTW 841
Query: 2494 QWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVI 2673
W++L+ KVKPL+ + + + + + K+ +++ E R+ ++ +++ E A +
Sbjct: 842 VWFKLYGKVKPLINSGKIEAQYEKLQETVATLKDTVVQEEEKKRQLQEGAERLNKETADL 901
Query: 2674 QEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETV 2853
QL+ ++ E+++ + + LE + D +L ++
Sbjct: 902 LAQLEASKGSTREVEERMTAMNEQKVALEGKLGDANKKLEAEEARAVEINKQKKLVEAEC 961
Query: 2854 RDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLT 3033
D +K + + LT
Sbjct: 962 ADLKKNCQDVDLSLRKVEAEKNAKEHQIRALQDEMRQQDENISKLNKERKNQEEQNKKLT 1021
Query: 3034 TQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLA 3213
L EE+ K K +L L + EQ + RE++ +++++++KRK EL+ +++ L
Sbjct: 1022 EDLQAAEEQNLAANKLKTKLMQSLEDSEQTMEREKRNRADMDKNKRKAEGELKIAQETLE 1081
Query: 3214 EKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERN 3393
E + N L +++ EL + + ++E A V +QK ++ + + +L + + E++
Sbjct: 1082 ELNKSKSDAENALRRKETELHNLGMKLEDEQAAVAKLQKGIQQDEARVKDLHDQLADEKD 1141
Query: 3394 ARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEG 3573
AR +A+ +R + A+ +++ + D+ +L +KD E+ +R +E+
Sbjct: 1142 ARQRADRSRADQQAEYDELTEQLEDQSRATAAQIELGKKKDAELTKLRRDLEECGLKFGE 1201
Query: 3574 KIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQ----QNQADQERADMAQEIALLQASRA 3741
++ K K S ++EL DQIEQ +KQ+ ++EK+ Q + D+ A + QE L RA
Sbjct: 1202 QLTVLKKKGSDAIQELSDQIEQLQKQKGRIEKEKGHMQREFDESSAALDQEAKL----RA 1257
Query: 3742 DIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAF--ANM 3915
D ++ K HE L+E++ E + + R E L R EE E AN
Sbjct: 1258 DQERIAKGHEVRLLELRLKADEQSRQLQDFVSSKGRLNSENSDLARQVEELEAKIQAANR 1317
Query: 3916 QRRLATAXXXXXXXXXXXXXXTRLKIANI--NRARQLEDEKNALLDE---KEEAEGLRAH 4080
+ + R ++N+ N AR+LE K ++ DE K EA A
Sbjct: 1318 LKLQFSNELDHAKRQAEEESRERQNLSNLSKNLARELEQLKESIEDEVAGKNEASRQLAK 1377
Query: 4081 LEKEIHAARQGAGEARRKAEESVN-QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSK 4257
E+ R + + E + + +E++K+ + +Q L+ + ++
Sbjct: 1378 ASVELDQWR-----TKFETEGLIGADEFDEVKKRQNQKTSEIQDALDACNAKIVALENAR 1432
Query: 4258 KKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRE 4437
++ E + + +E E+ + EK+QK F+ + E + V L+ D ++ R
Sbjct: 1433 SRLTAEADANRLEAEHHAQAVSSLEKKQKAFDKVIDEWKKKVDDLYLELDGAQRDARQLS 1492
Query: 4438 TRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELN 4617
L + D + + +E R ++L E +D + + G+ H L K R LE E
Sbjct: 1493 GEAHKLRGQHDTLADQVEGLRRENKALSDETRDLTESLSEGGRATHALSKNLRRLEMEKE 1552
Query: 4618 DMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLE 4797
+++ ++E E L+ E LR ++ +++E ++ I+ K+ E E R+ + I ++
Sbjct: 1553 ELQRGLDEAEAALESEESKALRCQIEVSQIRAEIEKRIAEKEEEFENHRKVHQQTIDSIQ 1612
Query: 4798 NELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECE 4977
L++E + KS +KK+E I ELE L+ AN+ E+ E Q +
Sbjct: 1613 ATLDSETKAKSELFRVKKKLEADINELEIALDHANKANEDAQKNIRRYLDQIRELQQTVD 1672
Query: 4978 EARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARK--QXXXXXXXXXXXRAKG 5151
E ++ +E+ L A+RK + E+E+L E + +AR+ +
Sbjct: 1673 EEQKRREEFREHLLAAERKLAVAKQEQEELIVKLEAIERARRVVESSVKEHQEHNNELNS 1732
Query: 5152 GGIS-SEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQK 5328
++ + K +L+ +IA + + D+ R+A ++ DL E+ +Q+
Sbjct: 1733 QNVALATAKSQLDNEIALLKSDIAEAHTELSASEDRGRRAASDAAKLAEDLRHEQEQSQQ 1792
Query: 5329 TEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANR 5508
E K+ LE + +D + + E+ + E +++ + L E + A++
Sbjct: 1793 LERFKKQLESAVKDLQERADAAEAAVMKGGAKAIQKAEQRLKAFQTDLETESRRAGEASK 1852
Query: 5509 AARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRN 5688
R ++++ + Q ++K+ ++ +EL+EK K + ++QL+EAE++ + +K+R
Sbjct: 1853 TLARADRKVREFEFQVAEDKKNYDKLQELVEKLTAKLKLQKKQLEEAEEQANSHLSKYRT 1912
Query: 5689 VQ---READDLLDANEQ 5730
VQ A++ D+ EQ
Sbjct: 1913 VQLSLETAEERADSAEQ 1929
Score = 145 bits (365), Expect = 2e-32
Identities = 197/915 (21%), Positives = 378/915 (40%), Gaps = 37/915 (4%)
Frame = +1
Query: 3115 EQDLNRERQYKSE-LEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTR 3291
E++ R+ Q +E L + LLA+LE SK E ++ +N Q + + +L +
Sbjct: 880 EEEKKRQLQEGAERLNKETADLLAQLEASKGSTREVEERMTAMNEQKVALEGKLGDANKK 939
Query: 3292 YDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDK 3471
+ E A + KQ + ++ +L+++ + +V L KV+ + K
Sbjct: 940 LEAEEARAVEINKQKKLVEAECADLKKNCQ--------------DVDLSLRKVEAEKNAK 985
Query: 3472 VDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQ 3651
+ LQD M ++DE ++ K+ +++ Q ++L + ++ ++Q
Sbjct: 986 EHQIRALQDEMRQQDENIS---------------KLNKERKNQEEQNKKLTEDLQAAEEQ 1030
Query: 3652 RSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTL 3831
K + + Q D Q + + +RAD+DK ++ E L Q L E ++ K
Sbjct: 1031 NLAANKLKTKLMQSLEDSEQTMEREKRNRADMDKNKRKAEGELKIAQETLEELNKSKSDA 1090
Query: 3832 IDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRA 4011
+ L R EL +L E+E+ A A +Q+ + ++A+ A
Sbjct: 1091 ENALRRKETELHNLGMKLEDEQAAVAKLQKGIQQDEARVKDLHD--------QLADEKDA 1142
Query: 4012 RQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEE-------------SVN 4152
RQ D A D++ E + L LE + A ++K E
Sbjct: 1143 RQRADRSRA--DQQAEYDELTEQLEDQSRATAAQIELGKKKDAELTKLRRDLEECGLKFG 1200
Query: 4153 QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSE 4332
+QL L+KK ++ L Q+E+ + K RI + K +Q+E ++SS L+ D E
Sbjct: 1201 EQLTVLKKKGSDAIQELSDQIEQLQKQKGRIEKEKGHMQREFDESSAALDQEAKLRADQE 1260
Query: 4333 KRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRR 4512
+ K E ++ E R L D S++L+D + L +E + +EE
Sbjct: 1261 RIAKGHEVRLLELR-------LKADEQSRQLQDFVSSKGRLNSENSDLARQVEE------ 1307
Query: 4513 SLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEV 4692
L+ ++Q + K F +EL+ AKR E E + R + L NL E +L+ +
Sbjct: 1308 -LEAKIQAANRLKLQFS---NELDHAKRQAEEESRE-RQNLSNLSKNLA-RELEQLKESI 1361
Query: 4693 TNQ-ALKSESDRAISNKDVEAEEKR-----RGLL-----KQIRDLENELENEKRGKSGAV 4839
++ A K+E+ R ++ VE ++ R GL+ +++ +N+ +E + A
Sbjct: 1362 EDEVAGKNEASRQLAKASVELDQWRTKFETEGLIGADEFDEVKKRQNQKTSEIQDALDAC 1421
Query: 4840 SHR-KKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXE-YQIECEEARQAKEDIAAL 5013
+ + +EN L + + ANRL+ E+ + + +E ++ +D+
Sbjct: 1422 NAKIVALENARSRLTAEAD-ANRLEAEHHAQAVSSLEKKQKAFDKVIDEWKKKVDDLYLE 1480
Query: 5014 LREADRKFRAVEAEREQLREAN-------EGLMQARKQXXXXXXXXXXXRAKGGGIS--- 5163
L A R R + E +LR + EGL + K ++GG +
Sbjct: 1481 LDGAQRDARQLSGEAHKLRGQHDTLADQVEGLRRENKALSDETRDLTESLSEGGRATHAL 1540
Query: 5164 SEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEK 5343
S+ RRLE + + ++ E K + Q+++ QI + E EK
Sbjct: 1541 SKNLRRLEMEKEELQRGLDEAEAALESEESKALRCQIEVSQI------------RAEIEK 1588
Query: 5344 QSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRL 5523
+I E E ++ + +++ ++ L+ E + K+ R ++L
Sbjct: 1589 ------------RIAEKEEEFENHRKVHQQTIDS----IQATLDSETKAKSELFRVKKKL 1632
Query: 5524 EKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREA 5703
E +N+ + +ANE A++ + + + R L++ +DE + + R + R A
Sbjct: 1633 EADINELEIALDHANKANEDAQKNIRRYLDQIRELQQTVDEEQ----KRREEFREHLLAA 1688
Query: 5704 DDLLDANEQLTRELM 5748
+ L +Q EL+
Sbjct: 1689 ERKLAVAKQEQEELI 1703
>gi|42656791|ref|XP_036988.9| KIAA1000 protein [Homo sapiens]
Length = 1946
Score = 1011 bits (2614), Expect = 0.0
Identities = 624/1903 (32%), Positives = 1011/1903 (52%), Gaps = 19/1903 (0%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETND-EVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMS 252
+K CW+PD ++ +K +D V+VE D ++I D +Q+ NPP+F+ IEDM+
Sbjct: 51 KKKCWIPDGENAYIEAEVKGSEDDGTVIVETAD-GESLSIKEDKIQQMNPPEFEMIEDMA 109
Query: 253 ELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMP 432
LT+LNEASVLH LK RY +IYTYSGLFCV INPYK LP+Y ++++ +KGK+R E P
Sbjct: 110 MLTHLNEASVLHTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAP 169
Query: 433 PHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAA 612
PHIFA+A+ A++ ML RE+QSIL TGESGAGKT N+K +IQY A +A +
Sbjct: 170 PHIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIES------- 222
Query: 613 QQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYIS 792
R G LE Q++QAN ILEAFGN+KT++NDNSSRFGKFIR++F G +S
Sbjct: 223 ----------RKKQGALEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLS 272
Query: 793 GANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGI 966
+I+ YLLEKSRV+ Q ER++HIFYQIL G KE + LL + ++ F +
Sbjct: 273 SVDIDIYLLEKSRVIFQQAGERNYHIFYQILSG--QKELHDLLLVSANPSDFHFCSCGAV 330
Query: 967 TLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDD 1146
T+ ++DD +E +T +M I+GF DE ++ A++ GN++F Q+ + +Q
Sbjct: 331 TVESLDDAEELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGT 390
Query: 1147 RVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKW 1326
K L+G+ EL K + PRIKVG E+V + Q EQ AV A++K+ YER+FKW
Sbjct: 391 ENADKAAFLMGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVTCAVGALSKSMYERMFKW 450
Query: 1327 LVTRINKSLD-RTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFIL 1503
LV RIN++LD + RQ FIGILDI GFEI + NS EQ+CIN+TNEKLQQ FN MF+L
Sbjct: 451 LVARINRALDAKLSRQ--FFIGILDITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVL 508
Query: 1504 EQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH 1683
EQEEY++E IEW I FGLDLQ IDLIEKPMG+L++L+EEC+FPKA D +F KL H
Sbjct: 509 EQEEYKKESIEWVSIGFGLDLQACIDLIEKPMGILSILEEECMFPKATDLTFKTKLFDNH 568
Query: 1684 ---NKHPKFIVPDMRS-KSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPF 1851
+ H + PD + ++HF +VHYAG V Y+ WL KN D LNE VV + Q S++
Sbjct: 569 FGKSVHLQKPKPDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRL 628
Query: 1852 VAGIWKDAEFAGICAAEMNETAFGMRSRK--GMFRTVSQLHKEQLTKLMTTLRNTSPHFV 2025
+A ++++ + + FG + RK F+TV+ LHKE L KLMT L++T+PHFV
Sbjct: 629 LASLFEN------YMSTDSAIPFGEKKRKKGASFQTVASLHKENLNKLMTNLKSTAPHFV 682
Query: 2026 RCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVI 2205
RCI PN K G ++ LVL+QLRCNGVLEG RICR+GFPNR+ + +F+ RY IL P
Sbjct: 683 RCINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYCILNPRTF 742
Query: 2206 PKN-FIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQA 2382
PK+ F+ +++ +++ +L+ID YR G +KVFF+ G L LE RD +L+ + FQA
Sbjct: 743 PKSKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFTLFQA 802
Query: 2383 QCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIR 2562
+ +G L R + N A++ ++NW W RLF K+KPL++ + +E+
Sbjct: 803 RAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVKSSEVGEEVA 862
Query: 2563 AKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQT 2742
+E ++ L K E E + K + E+ + QLQ E E A +++ L
Sbjct: 863 GLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIK 922
Query: 2743 RNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTN 2922
+LE V ++ +R+ RK + + +K
Sbjct: 923 SKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRT 982
Query: 2923 VDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQ 3102
+ + L EE+ KA +LE Q
Sbjct: 983 TEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQ 1042
Query: 3103 LHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQ 3282
+ ELE L +ER+ + E+ KL L+ +++ + L +L K++ EL
Sbjct: 1043 VDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQM 1102
Query: 3283 LTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDV 3462
++ + E V +QK ++++QT I +L+E +E ER R K E R ++ L + +
Sbjct: 1103 NSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADL-NER 1161
Query: 3463 LDKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQ 3639
L++V +++ Q ++ +++ + R +E+ E K + + + EL Q+E
Sbjct: 1162 LEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVEN 1221
Query: 3640 HKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEH 3819
++ + +LEK ++ E D+ + + ++A+ +K ++E L E A L + +
Sbjct: 1222 LQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQL 1281
Query: 3820 KRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIAN 3999
L Q + E R EE+E + R + T+ + A
Sbjct: 1282 ANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSAL 1341
Query: 4000 INRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKK 4179
+ ++ + + + L ++ EE + ++A L + + + R K E +V Q+ E+L
Sbjct: 1342 AHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDA 1401
Query: 4180 NLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKF 4350
LQ+ E VA R + +++ ++Q EL D+ +L VR++ +++Q +
Sbjct: 1402 KKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQS 1461
Query: 4351 ESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQEL 4530
+A+ + +++ DA +E++ T +L L N + E R ++LQ+E+
Sbjct: 1462 GKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEI 1521
Query: 4531 QDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALK 4710
+ + + KN+ E+EK K+ +E E +++V +EE E L+ E L ++ K
Sbjct: 1522 SNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAK 1581
Query: 4711 SESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
+E +R +S KD E E RR I L++ L++E + + +KK+E + E+E QL
Sbjct: 1582 AELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQL 1641
Query: 4891 EVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLR 5070
ANR E + Q++ +++ Q D+ + A+R+ +++E E LR
Sbjct: 1642 SCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLR 1701
Query: 5071 EANE----GLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNC 5238
E G + ++ + + S +K++LEA +A+ C
Sbjct: 1702 SLQEQTERGRRLSEEELLEATERINLFYTQNTSLLS-QKKKLEADVARMQKEAEEVVQEC 1760
Query: 5239 ELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRA 5418
+ A +K +KA ++ ++ +L ++ E ++++E++ D + ++ E E A +
Sbjct: 1761 QNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGS 1820
Query: 5419 RAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELL 5598
R Q+ LE++V+ LE +L E + A R ARRLE+ + + T Q E++K+ + + +
Sbjct: 1821 RKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQM 1880
Query: 5599 EKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANE 5727
+K LK +N ++Q++ AE + ++ +K++ Q E +++ + E
Sbjct: 1881 DKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAE 1923
Score = 136 bits (342), Expect = 7e-30
Identities = 180/846 (21%), Positives = 369/846 (43%), Gaps = 34/846 (4%)
Frame = +1
Query: 3028 LTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDH 3207
L TQ+ D +E+ + + ++E + +L QDL LE+ LA+LE +K
Sbjct: 1123 LQTQIKDLKEKLEAERTTRAKMERERADLTQDL---ADLNERLEEVGGSSLAQLEITKKQ 1179
Query: 3208 ----------LAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANV-TLMQKQMRDMQTT 3354
+ E E + L KR + +L E V ++K D+Q
Sbjct: 1180 ETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLE 1239
Query: 3355 IDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATML-QDLMSRKDE---E 3522
+D+L +E A+ AE ++ E+ + K+D+ T L DL ++K + E
Sbjct: 1240 VDDLLTRVEQMTRAKANAE----KLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSE 1295
Query: 3523 VNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRS----QLEKQQNQAD- 3687
R +E+ + + ++ +K+ F+RQ+E+L Q+E+ K +S L+K Q D
Sbjct: 1296 SGEFLRRLEE-KEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDL 1354
Query: 3688 -QERADMAQEI-----ALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLER 3849
+E+ + QE+ L A++ + R +E ++++ +L ++ K+ L +L+
Sbjct: 1355 LREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDL---EDAKKELAIRLQE 1411
Query: 3850 SRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDE 4029
+ + + N E A +Q L A RL + + L D
Sbjct: 1412 AAEAMGVANARNASLERARHQLQLELGDA---LSDLGKVRSAAARLDQKQLQSGKALADW 1468
Query: 4030 KNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN---LRDVEH 4200
K + EE++ L +KE+ A + + EES+ Q E LR++N ++ +
Sbjct: 1469 K----QKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQ-ETLRRENKNLQEEISN 1523
Query: 4201 LQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVA 4380
L Q+ E + + KK I++E + + LE + +E + F+ ++ E +
Sbjct: 1524 LTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAE 1583
Query: 4381 VQKALLDRDAMSQELRDRETRVL-SLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDD 4557
+++ L ++D + R ++ + SL + +D + E R+++ ++++L +
Sbjct: 1584 LERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSC 1643
Query: 4558 FGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVT---NQALKSESDRA 4728
+ V E K+ L+ ++ D+++Q L+D+ Q+ D + ++ V N L+SE +
Sbjct: 1644 ANRQVSEATKSLGQLQIQIKDLQMQ---LDDSTQLNSDLKEQVAVAERRNSLLQSELEDL 1700
Query: 4729 ISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRL 4908
S ++ + E RR +++ + + + +S +KK+E + ++++ A +
Sbjct: 1701 RSLQE-QTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKE---AEEV 1756
Query: 4909 KEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANE-G 5085
+E E EE ++ ++ IA L R + + + +++L EA +
Sbjct: 1757 VQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMA 1816
Query: 5086 LMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRK 5265
LM +RKQ R G + E +R EA+ + + DK+
Sbjct: 1817 LMGSRKQ---IQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNL 1873
Query: 5266 AQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEA 5445
+++Q + L ++ Q AE Q+ + ++ YK + EL + + RA++A E+
Sbjct: 1874 SRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSK-YKKQQHELN---EVKERAEVA--ES 1927
Query: 5446 KVQYLE 5463
+V L+
Sbjct: 1928 QVNKLK 1933
Score = 65.5 bits (158), Expect = 2e-08
Identities = 80/413 (19%), Positives = 169/413 (40%), Gaps = 14/413 (3%)
Frame = +1
Query: 4555 DFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDR-AI 4731
+ G+ V L++ L+ L Q EEL+ A+ L E + L+ ++++ +
Sbjct: 856 EVGEEVAGLKEECAQLQKALEKSEFQREELK-----AKQVSLTQEKNDLILQLQAEQETL 910
Query: 4732 SNKDVEAE---EKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVAN 4902
+N + + E + + L ++++L +E E+ S + +K+E++ EL+++++
Sbjct: 911 ANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDL- 969
Query: 4903 RLKEEYXXXXXXXXXXXXEYQIE--CEEARQAKEDIAALLREA-------DRKFRAVEAE 5055
E E++++ EE EDI+ L R A + + E
Sbjct: 970 ----ETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHME 1025
Query: 5056 REQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSN 5235
E+L ++ ++ +Q R K E +LE + +S+
Sbjct: 1026 EEKLSSLSKANLKLEQQVDELEGALEQER-KARMNCERELHKLEGNLKLNRESMENLESS 1084
Query: 5236 CELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSR 5415
++ RK +++L Q+ + + E+ L + + + L+ +D K K+ E E +++
Sbjct: 1085 QRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKL-EAERTTRAK 1143
Query: 5416 ARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKEL 5595
+ A L + L ++L G A ++ E + + E+ E
Sbjct: 1144 MERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSAS 1203
Query: 5596 LEKSNLKN-RNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
L+K + + L Q++ + + ++Q E DDLL EQ+TR N
Sbjct: 1204 LKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKAN 1256
Score = 54.3 bits (129), Expect = 4e-05
Identities = 67/340 (19%), Positives = 123/340 (35%), Gaps = 8/340 (2%)
Frame = +1
Query: 4738 KDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEE 4917
K E E+ GL ++ L+ LE K E Q EL+ + + K +
Sbjct: 853 KSSEVGEEVAGLKEECAQLQKALE--------------KSEFQREELKAKQVSLTQEKND 898
Query: 4918 YXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQL----REANEG 5085
+ +CE ++K + A ++E + E +L R+ +
Sbjct: 899 LILQLQAEQETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDE 958
Query: 5086 LMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRK 5265
+ +K+ S +EKR E K+ + +
Sbjct: 959 CFELKKEIDDLETMLVK--------SEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKV 1010
Query: 5266 AQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEA 5445
Q +Q DL ME E + SL ++N + ++ ELE + +A+M E
Sbjct: 1011 VQEAHQQTLDDLHME-------EEKLSSLSKANLKLEQQVDELEGALEQERKARMNC-ER 1062
Query: 5446 KVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRN 5625
++ LE L + + + R L + L + E K L+ + +
Sbjct: 1063 ELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKE 1122
Query: 5626 LRRQLDEAEDEMSRERTKHRNVQRE----ADDLLDANEQL 5733
L+ Q+ + ++++ ERT ++RE DL D NE+L
Sbjct: 1123 LQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERL 1162
>gi|25150292|ref|NP_510092.2| MYOsin heavy chain structural gene
(223.0 kD) (myo-2) [Caenorhabditis elegans]
gi|22265869|emb|CAA92183.2| C. elegans MYO-2 protein (corresponding
sequence T18D3.4) [Caenorhabditis elegans]
gi|22265924|emb|CAA92197.2| C. elegans MYO-2 protein (corresponding
sequence T18D3.4) [Caenorhabditis elegans]
Length = 1947
Score = 1009 bits (2608), Expect = 0.0
Identities = 624/1922 (32%), Positives = 1000/1922 (51%), Gaps = 33/1922 (1%)
Frame = +1
Query: 64 AWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIE 243
A+ +K W+PD +G++ G I + D V V + + T+ +D VQ+ NPPKF+K E
Sbjct: 26 AYDSKKNVWIPDSEDGYIEGVITKTAGDNVTVS-IGQGAEKTVKKDVVQEMNPPKFEKTE 84
Query: 244 DMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRH 423
DMS LT+LN+ASVL+NLK RY + LIYTYSGLFCVVINPYK+LPIY++ + F GK+R
Sbjct: 85 DMSNLTFLNDASVLYNLKARYAAMLIYTYSGLFCVVINPYKRLPIYTDSVARMFMGKRRT 144
Query: 424 EMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLN 603
EMPPH+FA++D AYR+MLQ E+QS+L TGESGAGKTENTKKVI Y A V GA + ++
Sbjct: 145 EMPPHLFAVSDEAYRNMLQNHENQSMLITGESGAGKTENTKKVISYFAAV-GAAQQETFG 203
Query: 604 AAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSG 783
A + + D LE Q++Q NP+LEAFGN+KTV+N+NSSRFGKFIRI+F G
Sbjct: 204 A---KKAATEEDKNKKKVTLEDQIVQTNPVLEAFGNAKTVRNNNSSRFGKFIRIHFSKQG 260
Query: 784 YISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLL-EGVDNYRFLVNR 960
++ +IE YLLEKSRV+RQA ER +HIFYQ+ K + LL + V +Y F+
Sbjct: 261 RVASCDIEHYLLEKSRVIRQAPGERCYHIFYQVFSDYLPNLKKDLLLNKPVKDYWFIAQA 320
Query: 961 GITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQ 1140
+ + ++D +E T + I+ F E R+V+A++ +GN++F Q + +QA
Sbjct: 321 ELIIDGINDKEEHQLTDEAFDILKFTPTEKMECYRLVAAMMHMGNMKFKQRPREEQAEPD 380
Query: 1141 DDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLF 1320
++ G+ E KA RPR+KVG E+VNK QN EQ +AV A+AK Y R+F
Sbjct: 381 GTDDAERAAKCFGIDSEEFLKALTRPRVKVGNEWVNKGQNIEQVNWAVGAMAKGLYSRIF 440
Query: 1321 KWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFI 1500
WLV + N++LD+ FIG+LDIAGFEIFD NSFEQ+ IN+ NEKLQQ FN+ MF+
Sbjct: 441 NWLVKKCNQTLDQKGISRDHFIGVLDIAGFEIFDFNSFEQLWINFVNEKLQQFFNHHMFV 500
Query: 1501 LEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKT 1680
LEQEEY REGI+W FIDFGLDLQ I+LIEKP+G++A+LDEEC+ PKA D + +KL
Sbjct: 501 LEQEEYAREGIQWTFIDFGLDLQACIELIEKPLGIIAMLDEECIVPKATDLTLAQKLIDQ 560
Query: 1681 H-NKHPKFIVP----DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTD 1845
H KHP F P ++++HFA+ HYAG V Y+ WL KN DPLN+ VV +M+ S +
Sbjct: 561 HLGKHPNFEKPKPPKGKQAEAHFAMRHYAGTVRYNCLNWLEKNKDPLNDTVVTVMKASKE 620
Query: 1846 -PFVAGIWKD--AEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSP 2016
+ +W+D + AA + + G F TVS L++E L KLMT L +T P
Sbjct: 621 HALIVEVWQDYTTQEEAAAAAAKGTAGAKKKGKSGSFMTVSMLYRESLNKLMTMLHSTHP 680
Query: 2017 HFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTP 2196
HF+RCIIPN +K SG I++ LVL QL CNGVLEGIRICR+GFPNR +F RY +L
Sbjct: 681 HFIRCIIPNEKKASGVIDAGLVLNQLTCNGVLEGIRICRKGFPNRTLHPDFVQRYALLAA 740
Query: 2197 DVIPKNFIDGKESVRKMITAL----DIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTAL 2364
D D K+ M+ L ++ +R+G +KVFF+ G++AHLE+ RD L L
Sbjct: 741 DESIIGKTDAKKGSALMLARLVKEKKLEEENFRVGLTKVFFKAGIVAHLEDLRDQSLAQL 800
Query: 2365 IMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTR 2544
I QAQ R + N ++ +LR W W++L+ KVKPL+ +
Sbjct: 801 ITGLQAQIRWYYQTIERKRRVEKITALKIIQRNIRSWAELRTWVWFKLYGKVKPLVNSGK 860
Query: 2545 TDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDI 2724
+ + + + K+ +++ E R+ ++ +++ E A + QL+ ++ E+++
Sbjct: 861 IEAQYEKLQETVATLKDTVVQEEEKKRQLQEGAERLNKETADLLAQLEASKGSTREVEER 920
Query: 2725 RGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXX 2904
+ + LE + D +L ++ D
Sbjct: 921 MTAMNEQKVALEGKLADASKKLEVEEARAVEINKQKKLVEAECADLKKNCQDVDLSLRKV 980
Query: 2905 XXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAK 3084
+K + + LT L EE+ K K
Sbjct: 981 EAEKNAKEHQIRALQDEMRQQDENISKLNKERKNQEEQNKKLTEDLQAAEEQNLAANKLK 1040
Query: 3085 GRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRD 3264
+L L + EQ + RE++ +++++++KRK EL+ +++ L E + N L +++
Sbjct: 1041 AKLMQSLEDSEQTMEREKRNRADMDKNKRKAEGELKIAQETLEELNKSKSDAENALRRKE 1100
Query: 3265 EELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLE 3444
EL + ++E A V +QK ++ + + +L + + E++AR +A+ +R + A+ +
Sbjct: 1101 TELHTLGMKLEDEQAAVAKLQKGIQQDEARVKDLHDQLADEKDARQRADRSRADQQAEYD 1160
Query: 3445 KVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELH 3624
++ + D+ +L +KD E+ +R +E+ ++ K K S ++EL
Sbjct: 1161 ELTEQLEDQARATAAQIELGKKKDAELTKLRRDLEESGLKFGEQLTVLKKKGSDAIQELS 1220
Query: 3625 DQIEQHKKQRSQLEKQ----QNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQ 3792
DQIEQ +KQ+ ++EK+ Q + D+ A + QE L RAD ++ K +E L+E++
Sbjct: 1221 DQIEQLQKQKGRIEKEKGHMQREFDESSAALDQEAKL----RADQERIAKGYEVRLLELR 1276
Query: 3793 ANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAF--ANMQRRLATAXXXXXXXXXX 3966
E + + R E L R EE E AN + +
Sbjct: 1277 LKADEQSRQLQDFVSSKGRLNSENSDLARQVEELEAKIQAANRLKLQFSNELDHAKRQAE 1336
Query: 3967 XXXXTRLKIANI--NRARQLEDEKNALLDE---KEEAEGLRAHLEKEIHAARQGAGEARR 4131
R ++N+ N AR+LE K ++ DE K EA +++ A + R
Sbjct: 1337 EESRERQNLSNLSKNLARELEQLKESIEDEVAGKNEA-------SRQLSKASVELDQWRT 1389
Query: 4132 KAEES---VNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
K E + +E++K+ + +Q L+ + ++ ++ E + + +E E
Sbjct: 1390 KFETEGLIGADEFDEVKKRQNQKTSEIQDALDACNAKIVALENARSRLTAEADANRLEAE 1449
Query: 4303 NVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKE 4482
+ + EK+QK F+ + E + V L+ D ++ R L + D + +
Sbjct: 1450 HHAQAVSSLEKKQKAFDKVIDEWKKKVDDLYLELDGAQRDARQLSGEAHKLRGQHDTLAD 1509
Query: 4483 HLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQI 4662
+E R +SL E +D + + G+ H L K R LE E +++ ++E E L+
Sbjct: 1510 QVEGLRRENKSLSDETRDLTESLSEGGRATHALSKNLRRLEMEKEELQRGLDEAEAALES 1569
Query: 4663 AEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVS 4842
E LR ++ +++E ++ I+ K+ E E R+ + I ++ L++E + KS
Sbjct: 1570 EESKALRCQIEVSQIRAEIEKRIAEKEEEFENHRKVHQQTIDSIQATLDSETKAKSELFR 1629
Query: 4843 HRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLRE 5022
+KK+E I ELE L+ AN+ E+ E Q +E ++ +E+ L
Sbjct: 1630 VKKKLEADINELEIALDHANKANEDAQKNIRRYLDQIRELQQTVDEEQKRREEFREHLLA 1689
Query: 5023 ADRKFRAVEAEREQLREANEGLMQARK--QXXXXXXXXXXXRAKGGGIS-SEEKRRLEAK 5193
A+RK + E+E+L E L +AR+ + ++ + K +L+ +
Sbjct: 1690 AERKLAVAKQEQEELIVKLEALERARRVVESSVKEHQEHNNELNSQNVALAAAKSQLDNE 1749
Query: 5194 IAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDY 5373
IA + + D+ R+A ++ DL E+ +Q+ E K+ LE + +D
Sbjct: 1750 IALLNSDIAEAHTELSASEDRGRRAASDAAKLAEDLRHEQEQSQQLERFKKQLESAVKDL 1809
Query: 5374 KAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQ 5553
+ + E+ + E +++ + L E + A++ R ++++ + Q
Sbjct: 1810 QERADAAEAAVMKGGAKAIQKAEQRLKAFQSDLETESRRAGEASKTLARADRKVREFEFQ 1869
Query: 5554 FEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQ---READDLLDAN 5724
++K+ ++ +EL+EK K + ++QL+EAE++ + +K+R VQ A++ D+
Sbjct: 1870 VAEDKKNYDKLQELVEKLTAKLKLQKKQLEEAEEQANSHLSKYRTVQLSLETAEERADSA 1929
Query: 5725 EQ 5730
EQ
Sbjct: 1930 EQ 1931
Score = 148 bits (374), Expect = 1e-33
Identities = 203/915 (22%), Positives = 383/915 (41%), Gaps = 37/915 (4%)
Frame = +1
Query: 3115 EQDLNRERQYKSE-LEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTR 3291
E++ R+ Q +E L + LLA+LE SK E ++ +N Q + + +L +
Sbjct: 882 EEEKKRQLQEGAERLNKETADLLAQLEASKGSTREVEERMTAMNEQKVALEGKLADASKK 941
Query: 3292 YDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDK 3471
+ E A + KQ + ++ +L+++ + +V L KV+ + K
Sbjct: 942 LEVEEARAVEINKQKKLVEAECADLKKNCQ--------------DVDLSLRKVEAEKNAK 987
Query: 3472 VDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQ 3651
+ LQD M ++DE ++ K+ +++ Q ++L + ++ ++Q
Sbjct: 988 EHQIRALQDEMRQQDENIS---------------KLNKERKNQEEQNKKLTEDLQAAEEQ 1032
Query: 3652 RSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTL 3831
K + + Q D Q + + +RAD+DK ++ E L Q L E ++ K
Sbjct: 1033 NLAANKLKAKLMQSLEDSEQTMEREKRNRADMDKNKRKAEGELKIAQETLEELNKSKSDA 1092
Query: 3832 IDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRA 4011
+ L R EL L E+E+ A A +Q+ + ++A+ A
Sbjct: 1093 ENALRRKETELHTLGMKLEDEQAAVAKLQKGIQQDEARVKDLHD--------QLADEKDA 1144
Query: 4012 RQLEDEKNALLDEKEEAEGLRAHLEKEIHA--ARQGAGEA--------RRKAEES---VN 4152
RQ D A D++ E + L LE + A A+ G+ RR EES
Sbjct: 1145 RQRADRSRA--DQQAEYDELTEQLEDQARATAAQIELGKKKDAELTKLRRDLEESGLKFG 1202
Query: 4153 QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSE 4332
+QL L+KK ++ L Q+E+ + K RI + K +Q+E ++SS L+ D E
Sbjct: 1203 EQLTVLKKKGSDAIQELSDQIEQLQKQKGRIEKEKGHMQREFDESSAALDQEAKLRADQE 1262
Query: 4333 KRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRR 4512
+ K +E ++ E R L D S++L+D + L +E + +EE
Sbjct: 1263 RIAKGYEVRLLELR-------LKADEQSRQLQDFVSSKGRLNSENSDLARQVEE------ 1309
Query: 4513 SLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEV 4692
L+ ++Q + K F +EL+ AKR E E + R + L NL E +L+ +
Sbjct: 1310 -LEAKIQAANRLKLQFS---NELDHAKRQAEEESRE-RQNLSNLSKNLA-RELEQLKESI 1363
Query: 4693 TNQ-ALKSESDRAISNKDVEAEEKR-----RGLL-----KQIRDLENELENEKRGKSGAV 4839
++ A K+E+ R +S VE ++ R GL+ +++ +N+ +E + A
Sbjct: 1364 EDEVAGKNEASRQLSKASVELDQWRTKFETEGLIGADEFDEVKKRQNQKTSEIQDALDAC 1423
Query: 4840 SHR-KKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXE-YQIECEEARQAKEDIAAL 5013
+ + +EN L + + ANRL+ E+ + + +E ++ +D+
Sbjct: 1424 NAKIVALENARSRLTAEAD-ANRLEAEHHAQAVSSLEKKQKAFDKVIDEWKKKVDDLYLE 1482
Query: 5014 LREADRKFRAVEAEREQLREAN-------EGLMQARKQXXXXXXXXXXXRAKGGGIS--- 5163
L A R R + E +LR + EGL + K ++GG +
Sbjct: 1483 LDGAQRDARQLSGEAHKLRGQHDTLADQVEGLRRENKSLSDETRDLTESLSEGGRATHAL 1542
Query: 5164 SEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEK 5343
S+ RRLE + + ++ E K + Q+++ QI + E EK
Sbjct: 1543 SKNLRRLEMEKEELQRGLDEAEAALESEESKALRCQIEVSQI------------RAEIEK 1590
Query: 5344 QSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRL 5523
+I E E ++ + +++ ++ L+ E + K+ R ++L
Sbjct: 1591 ------------RIAEKEEEFENHRKVHQQTIDS----IQATLDSETKAKSELFRVKKKL 1634
Query: 5524 EKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREA 5703
E +N+ + +ANE A++ + + + R L++ +DE + + R + R A
Sbjct: 1635 EADINELEIALDHANKANEDAQKNIRRYLDQIRELQQTVDEEQ----KRREEFREHLLAA 1690
Query: 5704 DDLLDANEQLTRELM 5748
+ L +Q EL+
Sbjct: 1691 ERKLAVAKQEQEELI 1705
>gi|127750|sp|P12845|MYSC_CAEEL Myosin heavy chain C (MHC C)
gi|295767|emb|CAA30855.1| myosin heavy chain 2 [Caenorhabditis
elegans]
Length = 1947
Score = 1006 bits (2600), Expect = 0.0
Identities = 624/1922 (32%), Positives = 998/1922 (51%), Gaps = 33/1922 (1%)
Frame = +1
Query: 64 AWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIE 243
A+ +K W+PD +G++ G I + D V V + + T+ +D VQ+ NPPKF+K E
Sbjct: 26 AYDSKKNVWIPDSEDGYIEGVITKTAGDNVTVS-IGQGAEKTVKKDVVQEMNPPKFEKTE 84
Query: 244 DMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRH 423
DMS LT+LN+ASVL+NLK RY + LIYTYSGLFCVVINPYK+LPIY+E + F GK+R
Sbjct: 85 DMSNLTFLNDASVLYNLKARYAAMLIYTYSGLFCVVINPYKRLPIYTESVARMFMGKRRT 144
Query: 424 EMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLN 603
EMPPH+FA++D AYR+MLQ E+QS+L TGESGAGKTENTKKVI Y A V GA + ++
Sbjct: 145 EMPPHLFAVSDEAYRNMLQNHENQSMLITGESGAGKTENTKKVISYFAAV-GAAQQETFG 203
Query: 604 AAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSG 783
A + + D LE Q++Q NP+LEAFGN+KTV+N+NSSRFGKFIRI+F G
Sbjct: 204 A---KKAATEEDKNKKKVTLEDQIVQTNPVLEAFGNAKTVRNNNSSRFGKFIRIHFSKQG 260
Query: 784 YISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLL-EGVDNYRFLVNR 960
++ +IE YLLEKSRV+RQA ERS+HIFYQ+ K + LL + V +Y F+
Sbjct: 261 RVASCDIEHYLLEKSRVIRQAPGERSYHIFYQVFSDYLPNLKKDLLLNKPVKDYWFIAQA 320
Query: 961 GITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQ 1140
+ + ++D +E T + I+ F E R+V+A++ +GN++F Q + +QA
Sbjct: 321 ELIIDGINDKEEHQLTDEAFDILKFTPTEKMECYRLVAAMMHMGNMKFKQRPREEQAEPD 380
Query: 1141 DDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLF 1320
++ G+ E KA RPR+KVG E+VNK Q EQ +AV A+AK Y R+F
Sbjct: 381 GTDDAERAAKCFGIDSEEFLKALTRPRVKVGNEWVNKGQKIEQVNWAVGAMAKGLYSRIF 440
Query: 1321 KWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFI 1500
WLV + N++LD+ FIG+LDIAGFEIFD NSFEQ+ IN+ NEKLQQ FN+ MF+
Sbjct: 441 NWLVKKCNQTLDQKGISRDHFIGVLDIAGFEIFDFNSFEQLWINFVNEKLQQFFNHHMFV 500
Query: 1501 LEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKT 1680
LEQEEY REGI+W FIDFGLDLQ I+LIEKP+G++A+LDEEC+ PKA D + +KL
Sbjct: 501 LEQEEYAREGIQWTFIDFGLDLQACIELIEKPLGIIAMLDEECIVPKATDLTLAQKLIDQ 560
Query: 1681 H-NKHPKFIVP----DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTD 1845
H KHP F P ++++HFA+ HYAG V Y+ WL KN DPLN+ VV +M+ S +
Sbjct: 561 HLGKHPNFEKPKPPKGKQAEAHFAMRHYAGTVRYNCLNWLEKNKDPLNDTVVTVMKASKE 620
Query: 1846 -PFVAGIWKD--AEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSP 2016
+ +W+D + AA + + G F TVS L++E L KLMT L +T P
Sbjct: 621 HALIVEVWQDYTTQEEAAAAAAKGTAGAKKKGKSGSFMTVSMLYRESLNKLMTMLHSTHP 680
Query: 2017 HFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTP 2196
HF+RCIIPN +K SG I++ LVL QL CNGVLEGIRICR+GFPNR +F RY +L
Sbjct: 681 HFIRCIIPNEKKASGVIDAGLVLNQLTCNGVLEGIRICRKGFPNRTLHPDFVQRYALLAA 740
Query: 2197 DVIPKNFIDGKESVRKMITAL----DIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTAL 2364
D D K+ M+ L ++ +R+G +KVFF+ G++AHLE+ RD L L
Sbjct: 741 DESIIGKTDAKKGSALMLARLVKEKKLEEENFRVGLTKVFFKAGIVAHLEDLRDQSLAQL 800
Query: 2365 IMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTR 2544
I QAQ R + N ++ +LR W W++L+ KVKPL+ +
Sbjct: 801 ITGLQAQIRWYYQTIERKRRVEKITALKIIQRNIRSWAELRTWVWFKLYGKVKPLVNSGK 860
Query: 2545 TDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDI 2724
+ + + + K+ +++ E R+ ++ +++ E A + QL+ ++ E+++
Sbjct: 861 IEAQYEKLQETVATLKDTVVQEEEKKRQLQEGAERLNKETADLLAQLEASKGSTREVEER 920
Query: 2725 RGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXX 2904
+ + LE + D +L ++ D
Sbjct: 921 MTAMNEQKVALEGKLADASKKLEVEEARAVEINKQKKLVEAECADLKKNCQDVDLSLRKV 980
Query: 2905 XXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAK 3084
+K + + LT L EE+ K K
Sbjct: 981 EAEKNAKEHQIRALQDEMRQQDENISKLNKERKNQEEQNKKLTEDLQAAEEQNLAANKLK 1040
Query: 3085 GRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRD 3264
+L L + EQ + RE++ +++++++KRK EL+ +++ L E + N L +++
Sbjct: 1041 AKLMQSLEDSEQTMEREKRNRADMDKNKRKAEGELKIAQETLEELNKSKSDAENALRRKE 1100
Query: 3265 EELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLE 3444
EL + ++E A V +QK ++ + + +L + + E++AR +A+ +R + A+ +
Sbjct: 1101 TELHTLGMKLEDEQAAVAKLQKGIQQDEARVKDLHDQLADEKDARQRADRSRADQQAEYD 1160
Query: 3445 KVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELH 3624
++ + D+ +L +KD E+ +R +E+ ++ K K S ++EL
Sbjct: 1161 ELTEQLEDQARATAAQIELGKKKDAELTKLRRDLEESGLKFGEQLTVLKKKGSDAIQELS 1220
Query: 3625 DQIEQHKKQRSQLEKQ----QNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQ 3792
DQIEQ +KQ+ ++EK+ Q + D+ A + QE L RAD ++ K +E E++
Sbjct: 1221 DQIEQLQKQKGRIEKEKGHMQREFDESCAALDQEAKL----RADQERIAKGYEVQTSELR 1276
Query: 3793 ANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAF--ANMQRRLATAXXXXXXXXXX 3966
E + + R E L R EE E AN + +
Sbjct: 1277 LKADEQSRQLQDFVSSKGRLNSENSDLARQVEELEAKIQAANRLKLQFSNELDHAKRQAE 1336
Query: 3967 XXXXTRLKIANI--NRARQLEDEKNALLDE---KEEAEGLRAHLEKEIHAARQGAGEARR 4131
R ++N+ N AR+LE K ++ DE K EA +++ A + R
Sbjct: 1337 EESRERQNLSNLSKNLARELEQLKESIEDEVAGKNEA-------SRQLSKASVELDQWRT 1389
Query: 4132 KAEES---VNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
K E + +E++K+ + +Q L+ + ++ ++ E + + +E E
Sbjct: 1390 KFETEGLIGADEFDEVKKRQNQKTSEIQDALDACNAKIVALENARSRLTAEADANRLEAE 1449
Query: 4303 NVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKE 4482
+ + EK+QK F+ + E + V L+ D ++ R L + D + +
Sbjct: 1450 HHAQAVSSLEKKQKAFDKVIDEWKKKVDDLYLELDGAQRDARQLSGEAHKLRGQHDTLAD 1509
Query: 4483 HLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQI 4662
+E R +SL E +D + + G+ H L K R LE E +++ ++E E L+
Sbjct: 1510 QVEGLRRENKSLSDETRDLTESLSEGGRATHALSKNLRRLEMEKEELQRGLDEAEAALES 1569
Query: 4663 AEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVS 4842
E LR ++ +++E ++ I+ K+ E E R+ + I ++ L++E + KS
Sbjct: 1570 EESKALRCQIEVSQIRAEIEKRIAEKEEEFENHRKVHQQTIDSIQATLDSETKAKSELFR 1629
Query: 4843 HRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLRE 5022
+KK+E I ELE L+ AN+ E+ E Q +E ++ +E+ L
Sbjct: 1630 VKKKLEADINELEIALDHANKANEDAQKNIRRYLDQIRELQQTVDEEQKRREEFREHLLA 1689
Query: 5023 ADRKFRAVEAEREQLREANEGLMQARK--QXXXXXXXXXXXRAKGGGIS-SEEKRRLEAK 5193
A+RK + E+E+L E L +AR+ + ++ + K +L+ +
Sbjct: 1690 AERKLAVAKQEQEELIVKLEALERARRVVESSVKEHQEHNNELNSQNVALAAAKSQLDNE 1749
Query: 5194 IAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDY 5373
IA + + D+ R+A ++ DL E+ +Q+ E K+ LE + +D
Sbjct: 1750 IALLNSDIAEAHTELSASEDRGRRAASDAAKLAEDLRHEQEQSQQLERFKKQLESAVKDL 1809
Query: 5374 KAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQ 5553
+ + E+ + E +++ + L E + A++ R ++++ + Q
Sbjct: 1810 QERADAAEAAVMKGGAKAIQKAEQRLKAFQSDLETESRRAGEASKTLARADRKVREFEFQ 1869
Query: 5554 FEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQ---READDLLDAN 5724
++K+ ++ +EL+EK K + ++QL+EAE++ + +K+R VQ A++ D+
Sbjct: 1870 VAEDKKNYDKLQELVEKLTAKLKLQKKQLEEAEEQANSHLSKYRTVQLSLETAEERADSA 1929
Query: 5725 EQ 5730
EQ
Sbjct: 1930 EQ 1931
Score = 147 bits (372), Expect = 2e-33
Identities = 203/915 (22%), Positives = 382/915 (41%), Gaps = 37/915 (4%)
Frame = +1
Query: 3115 EQDLNRERQYKSE-LEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTR 3291
E++ R+ Q +E L + LLA+LE SK E ++ +N Q + + +L +
Sbjct: 882 EEEKKRQLQEGAERLNKETADLLAQLEASKGSTREVEERMTAMNEQKVALEGKLADASKK 941
Query: 3292 YDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDK 3471
+ E A + KQ + ++ +L+++ + +V L KV+ + K
Sbjct: 942 LEVEEARAVEINKQKKLVEAECADLKKNCQ--------------DVDLSLRKVEAEKNAK 987
Query: 3472 VDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQ 3651
+ LQD M ++DE ++ K+ +++ Q ++L + ++ ++Q
Sbjct: 988 EHQIRALQDEMRQQDENIS---------------KLNKERKNQEEQNKKLTEDLQAAEEQ 1032
Query: 3652 RSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTL 3831
K + + Q D Q + + +RAD+DK ++ E L Q L E ++ K
Sbjct: 1033 NLAANKLKAKLMQSLEDSEQTMEREKRNRADMDKNKRKAEGELKIAQETLEELNKSKSDA 1092
Query: 3832 IDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRA 4011
+ L R EL L E+E+ A A +Q+ + ++A+ A
Sbjct: 1093 ENALRRKETELHTLGMKLEDEQAAVAKLQKGIQQDEARVKDLHD--------QLADEKDA 1144
Query: 4012 RQLEDEKNALLDEKEEAEGLRAHLEKEIHA--ARQGAGEA--------RRKAEES---VN 4152
RQ D A D++ E + L LE + A A+ G+ RR EES
Sbjct: 1145 RQRADRSRA--DQQAEYDELTEQLEDQARATAAQIELGKKKDAELTKLRRDLEESGLKFG 1202
Query: 4153 QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSE 4332
+QL L+KK ++ L Q+E+ + K RI + K +Q+E ++S L+ D E
Sbjct: 1203 EQLTVLKKKGSDAIQELSDQIEQLQKQKGRIEKEKGHMQREFDESCAALDQEAKLRADQE 1262
Query: 4333 KRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRR 4512
+ K +E Q +E R L D S++L+D + L +E + +EE
Sbjct: 1263 RIAKGYEVQTSELR-------LKADEQSRQLQDFVSSKGRLNSENSDLARQVEE------ 1309
Query: 4513 SLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEV 4692
L+ ++Q + K F +EL+ AKR E E + R + L NL E +L+ +
Sbjct: 1310 -LEAKIQAANRLKLQFS---NELDHAKRQAEEESRE-RQNLSNLSKNLA-RELEQLKESI 1363
Query: 4693 TNQ-ALKSESDRAISNKDVEAEEKR-----RGLL-----KQIRDLENELENEKRGKSGAV 4839
++ A K+E+ R +S VE ++ R GL+ +++ +N+ +E + A
Sbjct: 1364 EDEVAGKNEASRQLSKASVELDQWRTKFETEGLIGADEFDEVKKRQNQKTSEIQDALDAC 1423
Query: 4840 SHR-KKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXE-YQIECEEARQAKEDIAAL 5013
+ + +EN L + + ANRL+ E+ + + +E ++ +D+
Sbjct: 1424 NAKIVALENARSRLTAEAD-ANRLEAEHHAQAVSSLEKKQKAFDKVIDEWKKKVDDLYLE 1482
Query: 5014 LREADRKFRAVEAEREQLREAN-------EGLMQARKQXXXXXXXXXXXRAKGGGIS--- 5163
L A R R + E +LR + EGL + K ++GG +
Sbjct: 1483 LDGAQRDARQLSGEAHKLRGQHDTLADQVEGLRRENKSLSDETRDLTESLSEGGRATHAL 1542
Query: 5164 SEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEK 5343
S+ RRLE + + ++ E K + Q+++ QI + E EK
Sbjct: 1543 SKNLRRLEMEKEELQRGLDEAEAALESEESKALRCQIEVSQI------------RAEIEK 1590
Query: 5344 QSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRL 5523
+I E E ++ + +++ ++ L+ E + K+ R ++L
Sbjct: 1591 ------------RIAEKEEEFENHRKVHQQTIDS----IQATLDSETKAKSELFRVKKKL 1634
Query: 5524 EKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREA 5703
E +N+ + +ANE A++ + + + R L++ +DE + + R + R A
Sbjct: 1635 EADINELEIALDHANKANEDAQKNIRRYLDQIRELQQTVDEEQ----KRREEFREHLLAA 1690
Query: 5704 DDLLDANEQLTRELM 5748
+ L +Q EL+
Sbjct: 1691 ERKLAVAKQEQEELI 1705
>gi|21489941|ref|NP_659210.1| myosin, heavy polypeptide 2, skeletal
muscle, adult; myosin heavy chain 2A [Mus musculus]
gi|14250231|gb|AAH08538.1| Myosin, heavy polypeptide 2, skeletal
muscle, adult [Mus musculus]
Length = 1598
Score = 1004 bits (2597), Expect = 0.0
Identities = 573/1557 (36%), Positives = 897/1557 (56%), Gaps = 11/1557 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V + E F+ G+I+ + +V V+ + +T+ D + NPPK+DKIEDM+ +T+L
Sbjct: 39 FVAEPKESFVKGTIQSKDAGKVTVK-TEAGATLTVKEDQIFPMNPPKYDKIEDMAMMTHL 97
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 98 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVAAYRGKKRQEAPPHIFS 157
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A T +K A +
Sbjct: 158 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIA-VTGDKKKEEATSGKMQ 216
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 217 ---------GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIE 267
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPNV 981
YLLEKSRV Q + ERS+HIFYQI E E LL + +Y F+ I++ ++
Sbjct: 268 TYLLEKSRVTFQLKAERSYHIFYQITSN-KKPELIEMLLITTNPYDYPFVSQGEISVASI 326
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
DD +E +T +++ I+GF +DE SI ++ AV+ GN++F Q+++ +QA V K
Sbjct: 327 DDQEELMATDSAIDILGFTNDEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADK 386
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L GL +L KA PR+KVG E+V K Q EQ AV A+AKA YE++F W+VTRI
Sbjct: 387 AAYLQGLNSADLLKALCYPRVKVGNEYVTKGQTVEQVTNAVGALAKAMYEKMFLWMVTRI 446
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 447 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL + H K
Sbjct: 506 KEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSAN 565
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P + ++++HF+++HYAG VDY+ WL KN DPLNE VVGL Q S+ +A ++
Sbjct: 566 FQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNETVVGLYQKSSVKTLAYLFS 625
Query: 1870 DAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHE 2049
A+ A A+ G + + F+TVS L +E L KLMT LR+T PHFVRCIIPN
Sbjct: 626 GAQTAEAEASSGGAAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 685
Query: 2050 KKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDG 2226
K G + LVL QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L IP+ +ID
Sbjct: 686 KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQYIDS 745
Query: 2227 KESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSR 2406
K++ K++ ++DID Y+ G +KVFF+ G+L LEE RD KL LI QA CRGFL+R
Sbjct: 746 KKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQAMCRGFLAR 805
Query: 2407 RLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRA 2586
Y N A++ +++W W +LF K+KPLL+ T+ E+ +E +
Sbjct: 806 VEYQKMVERRESIFCIQYNIRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQK 865
Query: 2587 TKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYI 2766
TK+ L K E +E E+K+ ++ E+ +Q Q+Q E+E A+ ++ +L +LE
Sbjct: 866 TKDDLAKSEAKRKELEEKMVSLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAK 925
Query: 2767 VNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXX 2946
+ ++ +R +RK + + +K +
Sbjct: 926 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 985
Query: 2947 XXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDL 3126
+ L E++ KAK +LE Q+ +LE L
Sbjct: 986 TEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSL 1045
Query: 3127 NRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEES 3306
+E++ + +LE+ KRKL +L+ +++ + + + ++L+ +L K++ E+ + ++ ++E
Sbjct: 1046 EQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDERLKKKEFEMSNLQSKIEDEQ 1105
Query: 3307 ANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT 3486
A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L++ AT
Sbjct: 1106 AIGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEI-SERLEEAGGAT 1164
Query: 3487 MLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQL 3663
Q M++K E E +R +E+ E + K + V EL +QI+ ++ + +L
Sbjct: 1165 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1224
Query: 3664 EKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQL 3843
EK++++ E D+A + + ++ +++K + E + E+++ E L Q
Sbjct: 1225 EKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQVSELKSKEEEQQRLINDLTSQR 1284
Query: 3844 ERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLE 4023
R + E +R +E+E + + R + K A + +
Sbjct: 1285 GRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEVKAKNALAHALQSSR 1344
Query: 4024 DEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHL 4203
+ + L ++ EE + +A L++ + A + R K E Q+ EEL + + + L
Sbjct: 1345 HDCDLLREQYEEEQESKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1404
Query: 4204 QKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEER 4374
Q E E + + ++K+++Q E+ED +++E A+ +K+Q+ F+ +AE +
Sbjct: 1405 QAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWK 1464
Query: 4375 VAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKD 4554
++ + +A +E R T + + N + + LE R ++LQQE+ D
Sbjct: 1465 QKYEETHAELEASQKEARSLGTELFKMKNAYEESLDQLETLKRENKNLQQEISDLTEQIA 1524
Query: 4555 DFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDR 4725
+ GK +HELEK K+ +E E +++ +EE E +L+ E LR+++ +KSE DR
Sbjct: 1525 EGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEIDR 1581
Score = 123 bits (308), Expect = 6e-26
Identities = 137/758 (18%), Positives = 310/758 (40%), Gaps = 47/758 (6%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + ++ D + + + +R +LE++ +E+ D+ ++ AD ++
Sbjct: 853 EKEMATMKEEFQKTKDDLAKSEAKRKELEEKMVSLLKEKNDLQLQVQAEAEGLADAEERC 912
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ + +E L + + DE L + ++ E A ++
Sbjct: 913 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 972
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ K A N+ + L +E L +E +K +
Sbjct: 973 KE---------------------KHATENKVKNLTEEMAGL----DETIAKLTKEKKALQ 1007
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
A Q + + E+ VN L + + K + V+ L+ LE+ + + + ++K+K++ +L
Sbjct: 1008 EAHQQTLDDLQAEEDKVNT-LTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDL 1066
Query: 4279 ---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL 4449
++S M++EN + D ++K+FE + ++ ++A+ + +++++ + R+
Sbjct: 1067 KLAQESIMDIENEK-QQLDERLKKKEFEMSNLQSKIEDEQAI--GIQLQKKIKELQARIE 1123
Query: 4450 SLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRV 4629
L E++ + ++++ R L +EL++ ++ G + + EAE MR
Sbjct: 1124 ELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR 1183
Query: 4630 QME----------------------ELEDNLQIAEDARLRLEVTNQALKSESDRAISNKD 4743
+E EL + + + + +LE +K E D SN
Sbjct: 1184 DLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASN-- 1241
Query: 4744 VEAEEKRRGLLK--------QIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
VE K +G L+ Q+ +L+++ E ++R + S R +++ + GE +QL+
Sbjct: 1242 VETVSKAKGNLEKMCRTLEDQVSELKSKEEEQQRLINDLTSQRGRLQTESGEFSRQLDEK 1301
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLR----EADRKFRAVEAEREQL 5067
L + E + + EE +AK +A L+ + D E E+E
Sbjct: 1302 EALVSQLSRGKQAFTQQIEELKRQLEEEVKAKNALAHALQSSRHDCDLLREQYEEEQESK 1361
Query: 5068 REANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELA 5247
E L +A + + E K++L ++ + C
Sbjct: 1362 AELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASL 1421
Query: 5248 IDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES---GAQSRA 5418
+++ Q ++E + D+ + ++++ ++ ++K K E + +Q A
Sbjct: 1422 EKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKYEETHAELEASQKEA 1481
Query: 5419 RAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELL 5598
R+ L E+ L+ + R + L++ ++D T+Q + + + +++
Sbjct: 1482 RSLGTELFKMKNAYEESLD----QLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIK 1537
Query: 5599 EKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
++ + L+ L+EAE + E K +Q E + +
Sbjct: 1538 KQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQV 1575
Score = 48.1 bits (113), Expect = 0.003
Identities = 47/223 (21%), Positives = 98/223 (43%)
Frame = +1
Query: 3046 DHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMG 3225
D +R + +AK +L +L E+ + + LE+ K++L E+ED +
Sbjct: 1385 DAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNA 1444
Query: 3226 KVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNK 3405
L+ + D+ L +Y+E A + QK+ R + T + +++ E + ++
Sbjct: 1445 ACAALDKKQRNFDKILAEWKQKYEETHAELEASQKEARSLGTELFKMKNAYE---ESLDQ 1501
Query: 3406 AEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEE 3585
E +RE L++ D+ +++ E ++ E+ K+ +EQ + ++ +EE
Sbjct: 1502 LETLKRE-NKNLQQEISDLTEQIAEG-------GKRIHELEKIKKQVEQEKCELQAALEE 1553
Query: 3586 QKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQE 3714
+A E+ K R QLE Q +++ +R Q+
Sbjct: 1554 AEASLEH---------EEGKILRIQLELNQVKSEIDRKPAMQK 1587
>gi|11384452|pir||S05697 myosin heavy chain C [similarity] -
Caenorhabditis elegans
Length = 1968
Score = 1004 bits (2595), Expect = 0.0
Identities = 630/1943 (32%), Positives = 1007/1943 (51%), Gaps = 54/1943 (2%)
Frame = +1
Query: 64 AWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIE 243
A+ +K W+PD +G++ G I + D V V + + T+ +D VQ+ NPPKF+K E
Sbjct: 26 AYDSKKNVWIPDSEDGYIEGVITKTAGDNVTVS-IGQGAEKTVKKDVVQEMNPPKFEKTE 84
Query: 244 DMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRH 423
DMS LT+LN+ASVL+NLK RY + LIYTYSGLFCVVINPYK+LPIY++ + F GK+R
Sbjct: 85 DMSNLTFLNDASVLYNLKARYAAMLIYTYSGLFCVVINPYKRLPIYTDSVARMFMGKRRT 144
Query: 424 EMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLN 603
EMPPH+FA++D AYR+MLQ E+QS+L TGESGAGKTENTKKVI Y A V GA + ++
Sbjct: 145 EMPPHLFAVSDEAYRNMLQNHENQSMLITGESGAGKTENTKKVISYFAAV-GAAQQETFG 203
Query: 604 AAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSG 783
A + + D LE Q++Q NP+LEAFGN+KTV+N+NSSRFGKFIRI+F G
Sbjct: 204 A---KKAATEEDKNKKKVTLEDQIVQTNPVLEAFGNAKTVRNNNSSRFGKFIRIHFSKQG 260
Query: 784 YISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLL-EGVDNYRFLVNR 960
++ +IE YLLEKSRV+RQA ER +HIFYQ+ K + LL + V +Y F+
Sbjct: 261 RVASCDIEHYLLEKSRVIRQAPGERCYHIFYQVFSDYLPNLKKDLLLNKPVKDYWFIAQA 320
Query: 961 GITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQ 1140
+ + ++D +E T + I+ F E R+V+A++ +GN++F Q + +QA
Sbjct: 321 ELIIDGINDKEEHQLTDEAFDILKFTPTEKMECYRLVAAMMHMGNMKFKQRPREEQAEPD 380
Query: 1141 DDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLF 1320
++ G+ E KA RPR+KVG E+VNK QN EQ +AV A+AK Y R+F
Sbjct: 381 GTDDAERAAKCFGIDSEEFLKALTRPRVKVGNEWVNKGQNIEQVNWAVGAMAKGLYSRIF 440
Query: 1321 KWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFI 1500
WLV + N++LD+ FIG+LDIAGFEIFD NSFEQ+ IN+ NEKLQQ FN+ MF+
Sbjct: 441 NWLVKKCNQTLDQKGISRDHFIGVLDIAGFEIFDFNSFEQLWINFVNEKLQQFFNHHMFV 500
Query: 1501 LEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKT 1680
LEQEEY REGI+W FIDFGLDLQ I+LIEKP+G++A+LDEEC+ PKA D + +KL
Sbjct: 501 LEQEEYAREGIQWTFIDFGLDLQACIELIEKPLGIIAMLDEECIVPKATDLTLAQKLIDQ 560
Query: 1681 H-NKHPKFIVP----DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTD 1845
H KHP F P ++++HFA+ HYAG V Y+ WL KN DPLN+ VV +M+ S +
Sbjct: 561 HLGKHPNFEKPKPPKGKQAEAHFAMRHYAGTVRYNCLNWLEKNKDPLNDTVVTVMKASKE 620
Query: 1846 -PFVAGIWKD--AEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSP 2016
+ +W+D + AA + + G F TVS L++E L KLMT L +T P
Sbjct: 621 HALIVEVWQDYTTQEEAAAAAAKGTAGAKKKGKSGSFMTVSMLYRESLNKLMTMLHSTHP 680
Query: 2017 HFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTP 2196
HF+RCIIPN +K SG I++ LVL QL CNGVLEGIRICR+GFPNR +F RY +L
Sbjct: 681 HFIRCIIPNEKKASGVIDAGLVLNQLTCNGVLEGIRICRKGFPNRTLHPDFVQRYALLAA 740
Query: 2197 DVIPKNFIDGKESVRKMITAL----DIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTAL 2364
D D K+ M+ L ++ +R+G +KVFF+ G++AHLE+ RD L L
Sbjct: 741 DESIIGKTDAKKGSALMLARLVKEKKLEEENFRVGLTKVFFKAGIVAHLEDLRDQSLAQL 800
Query: 2365 IMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTR 2544
I QAQ R + N ++ +LR W W++L+ KVKPL+ +
Sbjct: 801 ITGLQAQIRWYYQTIERKRRVEKITALKIIQRNIRSWAELRTWVWFKLYGKVKPLVNSGK 860
Query: 2545 TDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDI 2724
+ + + + K+ +++ E R+ ++ +++ E A + QL+ ++ E+++
Sbjct: 861 IEAQYEKLQETVATLKDTVVQEEEKKRQLQEGAERLNKETADLLAQLEASKGSTREVEER 920
Query: 2725 RGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXX 2904
+ + LE + D +L ++ D
Sbjct: 921 MTAMNEQKVALEGKLADASKKLEVEEARAVEINKQKKLVEAECADLKKNCQDVDLSLRKV 980
Query: 2905 XXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAK 3084
+K + + LT L EE+ K K
Sbjct: 981 EAEKNAKEHQIRALQDEMRQQDENISKLNKERKNQEEQNKKLTEDLQAAEEQNLAANKLK 1040
Query: 3085 GRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRD 3264
+L L + EQ + RE++ +++++++KRK EL+ +++ L E + N L +++
Sbjct: 1041 AKLMQSLEDSEQTMEREKRNRADMDKNKRKAEGELKIAQETLEELNKSKSDAENALRRKE 1100
Query: 3265 EELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLE 3444
EL + ++E A V +QK ++ + + +L + + E++AR +A+ +R + A+ +
Sbjct: 1101 TELHTLGMKLEDEQAAVAKLQKGIQQDEARVKDLHDQLADEKDARQRADRSRADQQAEYD 1160
Query: 3445 KVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELH 3624
++ + D+ +L +KD E+ +R +E+ ++ K K S ++EL
Sbjct: 1161 ELTEQLEDQARATAAQIELGKKKDAELTKLRRDLEESGLKFGEQLTVLKKKGSDAIQELS 1220
Query: 3625 DQIEQHKKQRSQLEKQ----QNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQ 3792
DQIEQ +KQ+ ++EK+ Q + D+ A + QE L RAD ++ K +E L+E++
Sbjct: 1221 DQIEQLQKQKGRIEKEKGHMQREFDESSAALDQEAKL----RADQERIAKGYEVRLLELR 1276
Query: 3793 ANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAF--ANMQRRLATAXXXXXXXXXX 3966
E + + R E L R EE E AN + +
Sbjct: 1277 LKADEQSRQLQDFVSSKGRLNSENSDLARQVEELEAKIQAANRLKLQFSNELDHAKRQAE 1336
Query: 3967 XXXXTRLKIANI--NRARQLEDEKNALLDE---KEEAEGLRAHLEKEIHAARQGAGEARR 4131
R ++N+ N AR+LE K ++ DE K EA +++ A + R
Sbjct: 1337 EESRERQNLSNLSKNLARELEQLKESIEDEVAGKNEA-------SRQLSKASVELDQWRT 1389
Query: 4132 KAEES---VNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
K E + +E++K+ + +Q L+ + ++ ++ E + + +E E
Sbjct: 1390 KFETEGLIGADEFDEVKKRQNQKTSEIQDALDACNAKIVALENARSRLTAEADANRLEAE 1449
Query: 4303 NVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKE 4482
+ + EK+QK F+ + E + V L+ D ++ R L + D + +
Sbjct: 1450 HHAQAVSSLEKKQKAFDKVIDEWKKKVDDLYLELDGAQRDARQLSGEAHKLRGQHDTLAD 1509
Query: 4483 HLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQI 4662
+E R +SL E +D + + G+ H L K R LE E +++ ++E E L+
Sbjct: 1510 QVEGLRRENKSLSDETRDLTESLSEGGRATHALSKNLRRLEMEKEELQRGLDEAEAALES 1569
Query: 4663 AEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVS 4842
E LR ++ +++E ++ I+ K+ E E R+ + I ++ L++E + KS
Sbjct: 1570 EESKALRCQIEVSQIRAEIEKRIAEKEEEFENHRKVHQQTIDSIQATLDSETKAKSELFR 1629
Query: 4843 HRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLRE 5022
+KK+E I ELE L+ AN+ E+ E Q +E ++ +E+ L
Sbjct: 1630 VKKKLEADINELEIALDHANKANEDAQKNIRRYLDQIRELQQTVDEEQKRREEFREHLLA 1689
Query: 5023 ADRKFRAVEAEREQLREANEGLMQARK--QXXXXXXXXXXXRAKGGGIS-SEEKRRLEAK 5193
A+RK + E+E+L E L +AR+ + ++ + K +L+ +
Sbjct: 1690 AERKLAVAKQEQEELIVKLEALERARRVVESSVKEHQEHNNELNSQNVALAAAKSQLDNE 1749
Query: 5194 IAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDY 5373
IA + + D+ R+A ++ DL E+ +Q+ E K+ LE + +
Sbjct: 1750 IALLNSDIAEAHTELSASEDRGRRAASDAAKLAEDLRHEQEQSQQLERFKKQLESAVKSV 1809
Query: 5374 K----------AKITELESGAQSRARAQMAAL-----------EAKVQYLEDQLNVEGQE 5490
++T+L+ Q RA A AA+ E +++ + L E +
Sbjct: 1810 HLFPPSQLLILLRVTDLKIDLQERADAAEAAVMKGGAKAIQKAEQRLKAFQSDLETESRR 1869
Query: 5491 KTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRE 5670
A++ R ++++ + Q ++K+ ++ +EL+EK K + ++QL+EAE++ +
Sbjct: 1870 AGEASKTLARADRKVREFEFQVAEDKKNYDKLQELVEKLTAKLKLQKKQLEEAEEQANSH 1929
Query: 5671 RTKHRNVQ---READDLLDANEQ 5730
+K+R VQ A++ D+ EQ
Sbjct: 1930 LSKYRTVQLSLETAEERADSAEQ 1952
Score = 148 bits (374), Expect = 1e-33
Identities = 203/915 (22%), Positives = 383/915 (41%), Gaps = 37/915 (4%)
Frame = +1
Query: 3115 EQDLNRERQYKSE-LEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTR 3291
E++ R+ Q +E L + LLA+LE SK E ++ +N Q + + +L +
Sbjct: 882 EEEKKRQLQEGAERLNKETADLLAQLEASKGSTREVEERMTAMNEQKVALEGKLADASKK 941
Query: 3292 YDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDK 3471
+ E A + KQ + ++ +L+++ + +V L KV+ + K
Sbjct: 942 LEVEEARAVEINKQKKLVEAECADLKKNCQ--------------DVDLSLRKVEAEKNAK 987
Query: 3472 VDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQ 3651
+ LQD M ++DE ++ K+ +++ Q ++L + ++ ++Q
Sbjct: 988 EHQIRALQDEMRQQDENIS---------------KLNKERKNQEEQNKKLTEDLQAAEEQ 1032
Query: 3652 RSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTL 3831
K + + Q D Q + + +RAD+DK ++ E L Q L E ++ K
Sbjct: 1033 NLAANKLKAKLMQSLEDSEQTMEREKRNRADMDKNKRKAEGELKIAQETLEELNKSKSDA 1092
Query: 3832 IDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRA 4011
+ L R EL L E+E+ A A +Q+ + ++A+ A
Sbjct: 1093 ENALRRKETELHTLGMKLEDEQAAVAKLQKGIQQDEARVKDLHD--------QLADEKDA 1144
Query: 4012 RQLEDEKNALLDEKEEAEGLRAHLEKEIHA--ARQGAGEA--------RRKAEES---VN 4152
RQ D A D++ E + L LE + A A+ G+ RR EES
Sbjct: 1145 RQRADRSRA--DQQAEYDELTEQLEDQARATAAQIELGKKKDAELTKLRRDLEESGLKFG 1202
Query: 4153 QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSE 4332
+QL L+KK ++ L Q+E+ + K RI + K +Q+E ++SS L+ D E
Sbjct: 1203 EQLTVLKKKGSDAIQELSDQIEQLQKQKGRIEKEKGHMQREFDESSAALDQEAKLRADQE 1262
Query: 4333 KRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRR 4512
+ K +E ++ E R L D S++L+D + L +E + +EE
Sbjct: 1263 RIAKGYEVRLLELR-------LKADEQSRQLQDFVSSKGRLNSENSDLARQVEE------ 1309
Query: 4513 SLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEV 4692
L+ ++Q + K F +EL+ AKR E E + R + L NL E +L+ +
Sbjct: 1310 -LEAKIQAANRLKLQFS---NELDHAKRQAEEESRE-RQNLSNLSKNLA-RELEQLKESI 1363
Query: 4693 TNQ-ALKSESDRAISNKDVEAEEKR-----RGLL-----KQIRDLENELENEKRGKSGAV 4839
++ A K+E+ R +S VE ++ R GL+ +++ +N+ +E + A
Sbjct: 1364 EDEVAGKNEASRQLSKASVELDQWRTKFETEGLIGADEFDEVKKRQNQKTSEIQDALDAC 1423
Query: 4840 SHR-KKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXE-YQIECEEARQAKEDIAAL 5013
+ + +EN L + + ANRL+ E+ + + +E ++ +D+
Sbjct: 1424 NAKIVALENARSRLTAEAD-ANRLEAEHHAQAVSSLEKKQKAFDKVIDEWKKKVDDLYLE 1482
Query: 5014 LREADRKFRAVEAEREQLREAN-------EGLMQARKQXXXXXXXXXXXRAKGGGIS--- 5163
L A R R + E +LR + EGL + K ++GG +
Sbjct: 1483 LDGAQRDARQLSGEAHKLRGQHDTLADQVEGLRRENKSLSDETRDLTESLSEGGRATHAL 1542
Query: 5164 SEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEK 5343
S+ RRLE + + ++ E K + Q+++ QI + E EK
Sbjct: 1543 SKNLRRLEMEKEELQRGLDEAEAALESEESKALRCQIEVSQI------------RAEIEK 1590
Query: 5344 QSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRL 5523
+I E E ++ + +++ ++ L+ E + K+ R ++L
Sbjct: 1591 ------------RIAEKEEEFENHRKVHQQTIDS----IQATLDSETKAKSELFRVKKKL 1634
Query: 5524 EKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREA 5703
E +N+ + +ANE A++ + + + R L++ +DE + + R + R A
Sbjct: 1635 EADINELEIALDHANKANEDAQKNIRRYLDQIRELQQTVDEEQ----KRREEFREHLLAA 1690
Query: 5704 DDLLDANEQLTRELM 5748
+ L +Q EL+
Sbjct: 1691 ERKLAVAKQEQEELI 1705
>gi|28422303|gb|AAH46881.1| Zgc:66156 protein [Danio rerio]
Length = 1622
Score = 989 bits (2557), Expect = 0.0
Identities = 570/1603 (35%), Positives = 922/1603 (56%), Gaps = 14/1603 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V D +E +L G+++ + + V+ + + VT+ D++ NPPKFDKIEDM+ +T+L
Sbjct: 38 FVVDADEMYLKGTLQSKEGGKATVK-THSGKTVTVKEDEIFPMNPPKFDKIEDMAMMTHL 96
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
NE +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y ++ ++GKKR E PPHIF+
Sbjct: 97 NEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYDSVVVTGYRGKKRIEAPPHIFS 156
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A + K
Sbjct: 157 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVSGGAKK---------- 206
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
Q+P G LE Q++ ANP+LEA+GN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 207 QEPVPGKMQGSLEDQIIAANPLLEAYGNAKTVRNDNSSRFGKFIRIHFATTGKLASADIE 266
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRF-LVNRG-ITLPNV 981
YLLEKSRV Q ERS+HIFYQ++ G E E LL + + + ++++G +T+ ++
Sbjct: 267 TYLLEKSRVTFQLSAERSYHIFYQLMTG-HKPELLEALLITTNPFDYPMISQGEVTVKSI 325
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
+DV+EF +T ++ I+GF +E +I ++ AV+ G ++F Q+++ +QA V K
Sbjct: 326 NDVEEFIATDTAIDILGFTAEEKIAIYKLTGAVMHHGGMKFKQKQREEQAEPDGTEVADK 385
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+ +L+GL ++ KA PR+KVG E V K Q Q AV A+ K+ YE++F W+V RI
Sbjct: 386 IAYLMGLNSADMLKALCYPRVKVGNEMVTKGQTVPQVNNAVSALCKSVYEKMFLWMVVRI 445
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEI D NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 446 NEMLD-TKQPRQFFIGVLDIAGFEIVDYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 504
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H K
Sbjct: 505 KEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLHDQHLGKSSA 564
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P ++++HF++ HYAG VDY+ WL KN DPLN++VV L Q S+ ++ ++
Sbjct: 565 FQKPKPAKGKAEAHFSLEHYAGTVDYNIVGWLDKNKDPLNDSVVQLYQKSSVKLLSFLY- 623
Query: 1870 DAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHE 2049
A AG AE G + + G F+TVS L +E L KLMT LR+T PHFVRC+IPN
Sbjct: 624 -AAHAG-AEAEGGGGKKGGKKKGGSFQTVSALFRENLGKLMTNLRSTHPHFVRCLIPNES 681
Query: 2050 KKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDG 2226
K G + + LV+ QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L VIP+ FID
Sbjct: 682 KTPGLMENFLVIHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASVIPEGQFIDN 741
Query: 2227 KESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSR 2406
K++ K++ ++D+D Y+ G +KVFF+ G+L LEE RD KL +L+ QA CRG++ R
Sbjct: 742 KKASEKLLGSIDVDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLASLVTMTQALCRGYVMR 801
Query: 2407 RLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRA 2586
+ + N +++ +++W W +L+ K+KPLL+ T+ E+ A +
Sbjct: 802 KEFVKMMERREAIYSIQYNIRSFMNVKHWPWMKLYFKIKPLLKSAETEKEMAAMKENYEK 861
Query: 2587 TKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYI 2766
KE L K +E E+K+ ++ E+ +Q Q+ ESEN ++ ++ L +LE
Sbjct: 862 MKEDLTKALAKKKELEEKMVSLLQEKNDLQLQVASESENLSDAEERCEGLIKSKIQLEAK 921
Query: 2767 VNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXX 2946
+ + +RL +RK + + +K +
Sbjct: 922 LKETTERLEDEEEINAGLTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 981
Query: 2947 XXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDL 3126
++ L E++ K+K +LE Q+ +LE L
Sbjct: 982 TEEMASQDESIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKSKSKLEQQVDDLEGSL 1041
Query: 3127 NRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEES 3306
+E++ + +LE+ KRKL +L+ +++ + + ++ ++ K+D E+ L++ ++E
Sbjct: 1042 EQEKKLRMDLERAKRKLEGDLKLAQESIMDLENDKQQSEEKIKKKDFEISQFLSKIEDEQ 1101
Query: 3307 ANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT 3486
+ +QK+++++Q I+EL E++E ER AR K E R ++ +LE++ + L++ AT
Sbjct: 1102 SLGAQLQKKIKELQARIEELEEEIEAERAARAKVEKQRADLSRELEEI-SERLEEAGGAT 1160
Query: 3487 MLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQL 3663
Q M++K E E +R +E+ E + K + V EL +QI+ ++ + +L
Sbjct: 1161 AAQIEMNKKREAEFQKLRRDLEESTLQHEATAAAPRKKQADSVAELGEQIDNLQRVKQKL 1220
Query: 3664 EKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLID-- 3837
EK++++ E D++ + + ++ +++K + E E++ ++DE R L D
Sbjct: 1221 EKEKSEYKMEIDDLSSNMEAVAKAKTNLEKICRTLEDQASELK---TKNDELVRQLNDIS 1277
Query: 3838 -QLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRAR 4014
Q R + E R EE+E + + R + K A + +
Sbjct: 1278 AQKARLQTENGEFGRQMEEKEALVSQLTRGKQAYTQQIEELKRHIEEEVKAKNALAHAVQ 1337
Query: 4015 QLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDV 4194
+ + L ++ EE + +A L++ + A + R K E Q+ EEL + +
Sbjct: 1338 SARHDCDLLREQFEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEESKKKLA 1397
Query: 4195 EHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMA 4365
+ LQ E E + + ++K+++Q E+ED +++E A + +K+Q+ F+ +A
Sbjct: 1398 QRLQDAEESIEAVNSKCASLEKTKQRLQGEVEDLMIDVERANALAANLDKKQRNFDKVLA 1457
Query: 4366 EERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSIS 4545
E + ++ + + +E R T + + N + + LE R ++LQQE+ D
Sbjct: 1458 EWKQKYEEGQAELEGAQKEARSLSTEIFKMKNSYEEALDQLETLKRENKNLQQEISDLTE 1517
Query: 4546 NKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDR 4725
+ GK++HELEKAK+++E+E +++ +EE E L+ E LR+++ +KSE DR
Sbjct: 1518 QLGETGKSIHELEKAKKTVESEKAEIQTALEEAEGTLEHEESKILRVQLELNQVKSEIDR 1577
Query: 4726 AISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKK 4854
++ KD E E+ +R + + +++ L++E R ++ A+ +KK
Sbjct: 1578 KLAEKDEEIEQIKRNSQRVMDSMQSTLDSEIRSRNDALRVKKK 1620
Score = 137 bits (345), Expect = 3e-30
Identities = 168/820 (20%), Positives = 333/820 (40%), Gaps = 29/820 (3%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLA---EKMGKVEELNN 3246
K ++ ++++DL + K ELE+ LL E D + +A E + EE
Sbjct: 850 KEMAAMKENYEKMKEDLTKALAKKKELEEKMVSLLQEKNDLQLQVASESENLSDAEERCE 909
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
L+K +L+ +L DEE N L K+ R ++ EL++D++ E
Sbjct: 910 GLIKSKIQLEAKLKETTERLEDEEEINAGLTAKK-RKLEDECSELKKDIDD-------LE 961
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E + +++ +E A + A +Q ++ +
Sbjct: 962 LTLAKVEKEKHATENKVKNLTEEMASQDESIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1021
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK 3753
+ + K+K +QV++L +EQ KK R LE+ + + + + + I L+ + ++
Sbjct: 1022 TLTKSKSKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDLENDKQQSEE 1081
Query: 3754 KRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLAT 3933
K K + + + + + E +++L QL++ EL R+ E EE A R
Sbjct: 1082 KIKKKDFEISQFLSKI----EDEQSLGAQLQKKIKELQA--RIEELEEEIEAERAARAKV 1135
Query: 3934 AXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQG 4113
RL+ A A Q+E +++K EAE +
Sbjct: 1136 EKQRADLSRELEEISERLEEAGGATAAQIE------MNKKREAEFQKL------------ 1177
Query: 4114 AGEARRKAEESVNQQLEEL---RKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELED 4284
RR EES Q RKK V L +Q++ + K+++ + K + + E++D
Sbjct: 1178 ----RRDLEESTLQHEATAAAPRKKQADSVAELGEQIDNLQRVKQKLEKEKSEYKMEIDD 1233
Query: 4285 SSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNE 4464
S +E V + + EK + E Q +E + D + ++L D + L E
Sbjct: 1234 LSSNMEAVAKAKTNLEKICRTLEDQASELKTK-------NDELVRQLNDISAQKARLQTE 1286
Query: 4465 VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEEL 4644
+EE + + L + Q ++ +++ E KAK +L + R + L
Sbjct: 1287 NGEFGRQMEEKEALVSQLTRGKQAYTQQIEELKRHIEEEVKAKNALAHAVQSARHDCDLL 1346
Query: 4645 EDNLQIAEDARLRL---------EVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLE 4797
+ + ++A+ L EV K E+D AI + E EE ++ L ++++D E
Sbjct: 1347 REQFEEEQEAKAELQRGMSKANSEVAQWRTKYETD-AIQRTE-ELEESKKKLAQRLQDAE 1404
Query: 4798 NELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECE 4977
+E + +++++ ++ +L +E AN L E++ + E
Sbjct: 1405 ESIEAVNSKCASLEKTKQRLQGEVEDLMIDVERANALAANLDKKQRNFDKVLAEWKQKYE 1464
Query: 4978 EARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGG 5157
E + E R + ++ E+ + E L + K + G
Sbjct: 1465 EGQAELEGAQKEARSLSTEIFKMKNSYEEALDQLETLKRENKNLQQEISDLTEQLGETGK 1524
Query: 5158 ISSE---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQK 5328
E K+ +E++ A+ + E K + Q++L Q+ +++ +R L +K
Sbjct: 1525 SIHELEKAKKTVESEKAEIQTALEEAEGTLEHEESKILRVQLELNQVKSEI--DRKLAEK 1582
Query: 5329 TEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAK 5448
E +E+ R+ + + ++S S R++ AL K
Sbjct: 1583 DE----EIEQIKRNSQRVMDSMQSTLDSEIRSRNDALRVK 1618
Score = 130 bits (328), Expect = 3e-28
Identities = 142/813 (17%), Positives = 330/813 (40%), Gaps = 17/813 (2%)
Frame = +1
Query: 3325 QKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLM 3504
+K+M M+ ++++ED+ A K + ++V+ L++ L E+ L D
Sbjct: 849 EKEMAAMKENYEKMKEDLT---KALAKKKELEEKMVSLLQEKNDLQLQVASESENLSDAE 905
Query: 3505 SRKDEEVNATKRAIEQIQHTMEGKIEEQ---------KAKFSRQVEELHDQIEQHKKQRS 3657
R + + + + +++ T E +E+ K K + EL I+ + +
Sbjct: 906 ERCEGLIKSKIQLEAKLKETTERLEDEEEINAGLTAKKRKLEDECSELKKDIDDLELTLA 965
Query: 3658 QLEKQQNQADQERADMAQEIALLQASRADIDKKRK-IHEAHLMEIQANLAESDEHKRTLI 3834
++EK+++ + + ++ +E+A S A + K++K + EAH + AE D+ TL
Sbjct: 966 KVEKEKHATENKVKNLTEEMASQDESIAKLTKEKKALQEAHQQTLDDLQAEEDK-VNTLT 1024
Query: 3835 DQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRAR 4014
+ ++D L E+E+ +++R K + + +
Sbjct: 1025 KSKSKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDLENDKQQSEEKIK 1084
Query: 4015 QLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDV 4194
+ + E + L + E+ + L A L+K+I +EL+ + +
Sbjct: 1085 KKDFEISQFLSKIEDEQSLGAQLQKKI----------------------KELQAR----I 1118
Query: 4195 EHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEER 4374
E L++++E A+ ++ + + + +ELE+ S LE + + KK E++ + R
Sbjct: 1119 EELEEEIEAERAARAKVEKQRADLSRELEEISERLEEAGGATAAQIEMNKKREAEFQKLR 1178
Query: 4375 VAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKD 4554
++++ L +A + R ++ DS++
Sbjct: 1179 RDLEESTLQHEATAAAPRKKQA-------------------------------DSVA--- 1204
Query: 4555 DFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAIS 4734
+ G+ + L++ K+ LE E ++ ++++++L N++ A+ LE + L+ ++
Sbjct: 1205 ELGEQIDNLQRVKQKLEKEKSEYKMEIDDLSSNMEAVAKAKTNLEKICRTLEDQAS---- 1260
Query: 4735 NKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKE 4914
E + K L++Q+ D+ + + +++ + GE +Q+E L
Sbjct: 1261 ----ELKTKNDELVRQLNDIS--------------AQKARLQTENGEFGRQMEEKEALVS 1302
Query: 4915 EYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA----DRKFRAVEAEREQLREANE 5082
+ E + EE +AK +A ++ A D E E+E E
Sbjct: 1303 QLTRGKQAYTQQIEELKRHIEEEVKAKNALAHAVQSARHDCDLLREQFEEEQEAKAELQR 1362
Query: 5083 GLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQR 5262
G+ +A + + E K++L ++ S C ++
Sbjct: 1363 GMSKANSEVAQWRTKYETDAIQRTEELEESKKKLAQRLQDAEESIEAVNSKCASLEKTKQ 1422
Query: 5263 KAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES---GAQSRARAQMA 5433
+ Q ++E + D+ L + ++++ ++ ++K K E ++ GAQ AR+
Sbjct: 1423 RLQGEVEDLMIDVERANALAANLDKKQRNFDKVLAEWKQKYEEGQAELEGAQKEARSLST 1482
Query: 5434 ALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNL 5613
+ E+ L+ + R + L++ ++D T+Q + ++ + ++ +
Sbjct: 1483 EIFKMKNSYEEALD----QLETLKRENKNLQQEISDLTEQLGETGKSIHELEKAKKTVES 1538
Query: 5614 KNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ ++ L+EAE + E +K VQ E + +
Sbjct: 1539 EKAEIQTALEEAEGTLEHEESKILRVQLELNQV 1571
Score = 70.9 bits (172), Expect = 4e-10
Identities = 102/520 (19%), Positives = 199/520 (37%), Gaps = 26/520 (5%)
Frame = +1
Query: 4258 KKIQQELEDSSMELENVRASHRDSEK---RQKKFESQMAEERVAVQKALLDRDAMSQELR 4428
K + E E ++M+ EN D K ++K+ E +M L + S+ L
Sbjct: 844 KSAETEKEMAAMK-ENYEKMKEDLTKALAKKKELEEKMVSLLQEKNDLQLQVASESENLS 902
Query: 4429 DRETRVLSLLN-------EVDIMKEHLEESDRVRRSL---QQELQDSISNKDDFGKNVHE 4578
D E R L+ ++ E LE+ + + L +++L+D S + K++ +
Sbjct: 903 DAEERCEGLIKSKIQLEAKLKETTERLEDEEEINAGLTAKKRKLEDECS---ELKKDIDD 959
Query: 4579 LEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEE 4758
LE +E E + +++ L + + +++ +L +AL+ + + D++AEE
Sbjct: 960 LELTLAKVEKEKHATENKVKNLTEEMASQDESIAKLTKEKKALQEAHQQTLD--DLQAEE 1017
Query: 4759 KRRGLL--------KQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKE 4914
+ L +Q+ DLE LE EK+ + ++K+E + ++ + K+
Sbjct: 1018 DKVNTLTKSKSKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDLENDKQ 1077
Query: 4915 EYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQ 5094
+ ++ + E+ + + ++E + +E E E R A + +
Sbjct: 1078 QSEEKIKKKDFEISQFLSKIEDEQSLGAQLQKKIKELQARIEELEEEIEAERAARAKVEK 1137
Query: 5095 ARKQXXXXXXXXXXXRAKGGG-----ISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQ 5259
R + GG I +KR E + + Q A ++
Sbjct: 1138 QRADLSRELEEISERLEEAGGATAAQIEMNKKREAEFQKLRRDLEESTLQHEATAAAPRK 1197
Query: 5260 RKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAAL 5439
++A E +++R KQ LE+ +YK +I +L S ++ A+A
Sbjct: 1198 KQADSVAELGEQIDNLQRV--------KQKLEKEKSEYKMEIDDLSSNMEAVAKA----- 1244
Query: 5440 EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKN 5619
KT + R LE +QA EL KN
Sbjct: 1245 -----------------KTNLEKICRTLE-----------------DQASEL----KTKN 1266
Query: 5620 RNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTR 5739
L RQL++ + +R +T++ R+ ++ QLTR
Sbjct: 1267 DELVRQLNDISAQKARLQTENGEFGRQMEEKEALVSQLTR 1306
Score = 57.8 bits (138), Expect = 3e-06
Identities = 48/192 (25%), Positives = 91/192 (47%)
Frame = +1
Query: 5167 EEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQ 5346
+EK L+ ++A + CE I + + + +L++ T L E +N A+K+
Sbjct: 885 QEKNDLQLQVASESENLSDAEERCEGLIKSKIQLEAKLKETTERLEDEEEINAGLTAKKR 944
Query: 5347 SLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLE 5526
LE + K I +LE ++ + A E KV+ L +++ Q+++ A +
Sbjct: 945 KLEDECSELKKDIDDLEL-TLAKVEKEKHATENKVKNLTEEM--ASQDESIAKLTKEK-- 999
Query: 5527 KRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREAD 5706
K L + QQ D+ +A E L KS K L +Q+D+ E + +E+ +++R A
Sbjct: 1000 KALQEAHQQTLDDLQAEEDKVNTLTKSKSK---LEQQVDDLEGSLEQEKKLRMDLER-AK 1055
Query: 5707 DLLDANEQLTRE 5742
L+ + +L +E
Sbjct: 1056 RKLEGDLKLAQE 1067
>gi|50757921|ref|XP_425359.1| PREDICTED: similar to Myosin heavy
chain, skeletal muscle, adult [Gallus gallus]
Length = 2076
Score = 986 bits (2550), Expect = 0.0
Identities = 628/1906 (32%), Positives = 1016/1906 (52%), Gaps = 49/1906 (2%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V E F+ G+I+ + +V V+ + +T+ D V NPPK+DKIEDM+ +T+L
Sbjct: 40 FVVHPKESFVKGTIQSKEGGKVTVK-TEGGETLTVKEDQVFSMNPPKYDKIEDMAMMTHL 98
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 99 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVLAYRGKKRQEAPPHIFS 158
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A + K + +
Sbjct: 159 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAASGEKKKEEQSGKMQ-- 216
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 217 ---------GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIE 267
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPNV 981
YLLEKSRV Q ERS+HIFYQI+ E + LL + +Y ++ IT+P++
Sbjct: 268 TYLLEKSRVTFQLPAERSYHIFYQIMSN-KKPELIDMLLITTNPYDYHYVSQGEITVPSI 326
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
DD +E +T +++ I+GF+ DE ++I ++ AV+ GNL+F Q+++ +QA V K
Sbjct: 327 DDQEELMATDSAIDILGFSADEKTAIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADK 386
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L+GL EL KA PR+KVG EFV K Q Q +V A+AKA YE++F W+V RI
Sbjct: 387 AAYLMGLNSAELLKALCYPRVKVGNEFVTKGQTVSQVHNSVGALAKAVYEKMFLWMVIRI 446
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 447 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H K
Sbjct: 506 KEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNN 565
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P ++++HF++VHYAG VDY+ WL KN DPLNE V+GL Q S+ +A ++
Sbjct: 566 FQKPKPAKGKAEAHFSLVHYAGTVDYNISGWLEKNKDPLNETVIGLYQKSSVKTLALLF- 624
Query: 1870 DAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHE 2049
A + G AE G + + F+TVS L +E L KLM LR+T PHFVRCIIPN
Sbjct: 625 -ATYGG--EAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMANLRSTHPHFVRCIIPNET 681
Query: 2050 KKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDG 2226
K G + LVL QLRCNGVLEGIRICR+GFP+RV + +F+ RY +L IP+ F+D
Sbjct: 682 KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRVLYADFKQRYRVLNASAIPEGQFMDS 741
Query: 2227 KESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSR 2406
K++ K++ ++D+D YR G +KVFF+ G+L LEE RD KL +I QA+CRGFL R
Sbjct: 742 KKASEKLLGSIDVDHTQYRFGHTKVFFKAGLLGLLEEMRDDKLAEIITRTQARCRGFLMR 801
Query: 2407 RLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRA 2586
Y N +++ +++W W +LF K+KPLL+ ++ E+ +E
Sbjct: 802 VEYRRMVERRESIFCIQYNVRSFMNVKHWPWMKLFFKIKPLLKSAESEKEMANMKEEFEK 861
Query: 2587 TKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYI 2766
TKE L K E +E E+K+ ++ E+ +Q Q+Q E+++ A+ ++ +L +LE
Sbjct: 862 TKEELAKSEAKRKELEEKMVVLLQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAK 921
Query: 2767 VNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXX 2946
+ ++ +R +RK + + +K +
Sbjct: 922 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 981
Query: 2947 XXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDL 3126
+ L E++ KAK +LE Q+ +LE L
Sbjct: 982 TEEMAVLDETIAKLTKEKKALQEAHQQTLDDLQVEEDKVNTLTKAKTKLEQQVDDLEGSL 1041
Query: 3127 NRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEES 3306
+E++ + +LE+ KRKL +L+ + D + + ++L+ +L K+D E+ ++ ++E
Sbjct: 1042 EQEKKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQ 1101
Query: 3307 ANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT 3486
A +QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ + L++ AT
Sbjct: 1102 ALGMQLQKKIKELQARIEELEEEIEAERTSRAKAEKHRADLSRELEEI-SERLEEAGGAT 1160
Query: 3487 MLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQL 3663
Q D+ +++ E +R +E+ E + K + EL +QI+ ++ + +L
Sbjct: 1161 AAQIDMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKL 1220
Query: 3664 EKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQL 3843
EK++++ E D+A + + ++A ++K + E L EI+ + +EH+R +I+ L
Sbjct: 1221 EKEKSELKMEIDDLASNMESVSKAKASLEKTCRALEDQLSEIK---TKEEEHQR-MINDL 1276
Query: 3844 ERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL--KIANIN-RAR 4014
R L E + +QR+ +L KI + R
Sbjct: 1277 NAQRARLQ-----TESGTNTMYLVQRKDFEISQIQSKIEDEQALGMQLQKKIKELQARIE 1331
Query: 4015 QLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEA------------RRKAE-ESVNQ 4155
+LE+E A + +AE RA L +E+ + EA +R+AE + + +
Sbjct: 1332 ELEEEIEAERTSRAKAEKHRADLSRELEEISERLEEAGGATAAQIEMNKKREAEFQKMRR 1391
Query: 4156 QLEE-----------LRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
LEE LRKK+ L +Q++ + K+++ + K +++ E++D + +E
Sbjct: 1392 DLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNME 1451
Query: 4303 NVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKE 4482
+V + + EK + E Q++E + + + + D T+ L E
Sbjct: 1452 SVSKAKANLEKMCRTLEDQLSEIKT-------KEEQNQRMINDLNTQRARLQTETGEYSR 1504
Query: 4483 HLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQI 4662
EE D + L + Q ++ +++ E KAK +L L R E L + +
Sbjct: 1505 QAEEKDALISQLSRGKQGFTQQIEELKRHLEEEIKAKNALAHALQSARHDCELLREQYEE 1564
Query: 4663 AEDARLRL---------EVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENE 4815
++A+ L EV K E+D AI + E EE ++ L ++++D E +E
Sbjct: 1565 EQEAKGELQRALSKANSEVAQWRTKYETD-AIQRTE-ELEEAKKKLAQRLQDAEEHVEAV 1622
Query: 4816 KRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAK 4995
+ +++++N++ +L +E +N E++ + EE +
Sbjct: 1623 NAKCASLEKTKQRLQNEVEDLMVDVERSNAACAALDKKQKNFDKILAEWKQKYEETQTEL 1682
Query: 4996 EDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSE-- 5169
E R + ++ E+ + E L + K A+GG E
Sbjct: 1683 EASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEIADLTEQIAEGGKAVHELE 1742
Query: 5170 -EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQ 5346
K+ +E + ++ +++ E K + Q++L QI ++ +++K + +
Sbjct: 1743 KVKKHVEQEKSELQASLEEAEASLEHEEGKILRLQLELNQIKSE------IDRKIAEKDE 1796
Query: 5347 SLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLE 5526
+++ R++ + ++S + R++ AL K + +E LN + + ANR A +
Sbjct: 1797 EIDQLKRNHLRIVESMQSTLDAEIRSRNEALRLK-KKMEGDLNEMEIQLSHANRMAAEAQ 1855
Query: 5527 KRLNDTTQQFEDEK--RANEQAKELLEKSNLKNRNLRRQLDEAEDE 5658
K L +T + K R A++ ++K + + + + ED+
Sbjct: 1856 KNLRNTQGTLKGGKGARGKTDARKSVQKVEKELKKKEKAVRLTEDQ 1901
Score = 185 bits (470), Expect = 1e-44
Identities = 200/950 (21%), Positives = 408/950 (42%), Gaps = 73/950 (7%)
Frame = +1
Query: 3040 LLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKL-------------- 3177
L D EER +K K +LE ++ E+ + E + +EL KRKL
Sbjct: 901 LADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL 960
Query: 3178 ---LAELEDSK-------DHLAEKMGKVEELNNQLMKRDEELQ--HQLTRYD--EESANV 3315
LA++E K +L E+M ++E +L K + LQ HQ T D E V
Sbjct: 961 ELTLAKVEKEKHATENKVKNLTEEMAVLDETIAKLTKEKKALQEAHQQTLDDLQVEEDKV 1020
Query: 3316 TLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ 3495
+ K ++ +D+L +E E+ R E +R++ L+ ++D ++ L
Sbjct: 1021 NTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLD 1080
Query: 3496 DLMSRKDEEVNATKRAIEQIQ---HTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLE 3666
+ + +KD E++ + IE Q ++ KI+E +A+ +EEL ++IE + R++ E
Sbjct: 1081 EKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQAR----IEELEEEIEAERTSRAKAE 1136
Query: 3667 KQQNQADQERADMA---QEIALLQASRADIDKKRKIHEAHLMEIQANLAESD-EHKRTL- 3831
K + +E +++ +E A++ D++KKR EA +++ +L E+ +H+ T
Sbjct: 1137 KHRADLSRELEEISERLEEAGGATAAQIDMNKKR---EAEFQKMRRDLEEATLQHEATAA 1193
Query: 3832 ------IDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKI 3993
D +++D+L RV+++ E + ++ + ++ K
Sbjct: 1194 ALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEI-------DDLASNMESVSKAKA 1246
Query: 3994 ANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAG-----------------E 4122
+ R LED+ + + ++EE + + L + + +G +
Sbjct: 1247 SLEKTCRALEDQLSEIKTKEEEHQRMINDLNAQRARLQTESGTNTMYLVQRKDFEISQIQ 1306
Query: 4123 ARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE 4302
++ + E+++ QL++ K+ +E L++++E ++ + + + + +ELE+ S LE
Sbjct: 1307 SKIEDEQALGMQLQKKIKELQARIEELEEEIEAERTSRAKAEKHRADLSRELEEISERLE 1366
Query: 4303 NVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNE-VDIMK 4479
+ + KK E++ + R +++A L +A + LR + + L E +D ++
Sbjct: 1367 EAGGATAAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQ 1426
Query: 4480 EHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQ 4659
++ ++ + L+ E+ D SN + K LEK R+LE +L++++ + E+ + +
Sbjct: 1427 RVKQKLEKEKSELKMEIDDLASNMESVSKAKANLEKMCRTLEDQLSEIKTKEEQNQRMIN 1486
Query: 4660 IAEDARLRLEVTNQALKSESDRAISNKDV---EAEEKRRGLLKQIRDLENELENEKRGKS 4830
R RL Q E R KD + ++G +QI +L+ LE E + K+
Sbjct: 1487 DLNTQRARL----QTETGEYSRQAEEKDALISQLSRGKQGFTQQIEELKRHLEEEIKAKN 1542
Query: 4831 GAV----SHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIEC----EEAR 4986
S R E + E++ E L+ +Y+ + EE
Sbjct: 1543 ALAHALQSARHDCELLREQYEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEELE 1602
Query: 4987 QAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISS 5166
+AK+ +A L++A+ AV A+ L +
Sbjct: 1603 EAKKKLAQRLQDAEEHVEAVNAKCASLEKT------------------------------ 1632
Query: 5167 EEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQ 5346
K+RL+ ++ + C A+DK++K ++I + QK E +
Sbjct: 1633 --KQRLQNEVEDLMVDVERSNAAC-AALDKKQK---NFDKILAE------WKQKYEETQT 1680
Query: 5347 SLERSNRDYKAKITEL--ESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARR 5520
LE S ++ ++ TEL A + + L+ + + L+ ++ ++ +A
Sbjct: 1681 ELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEIADLTEQIAEGGKAVHE 1740
Query: 5521 LEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRE 5670
LEK Q+ + + + E+A+ LE K L+ +L++ + E+ R+
Sbjct: 1741 LEKVKKHVEQEKSELQASLEEAEASLEHEEGKILRLQLELNQIKSEIDRK 1790
Score = 159 bits (401), Expect = 1e-36
Identities = 198/934 (21%), Positives = 394/934 (41%), Gaps = 53/934 (5%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + + +++L + + ELE+ LL E D + + A+ + EE +
Sbjct: 850 KEMANMKEEFEKTKEELAKSEAKRKELEEKMVVLLQEKNDLQLQVQAEADSLADAEERCD 909
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE N L K+ R ++ EL++D++ E
Sbjct: 910 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKDIDD-------LE 961
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQ------IQHTMEG 3573
+T +V + + V + +E +L + +++ +E A + A +Q ++
Sbjct: 962 LTLAKVEKEKHATENKVKNLTEEMAVLDETIAKLTKEKKALQEAHQQTLDDLQVEEDKVN 1021
Query: 3574 KIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK 3753
+ + K K +QV++L +EQ KK R LE+ + + + + I L+ + +D+
Sbjct: 1022 TLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDE 1081
Query: 3754 KRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLAT 3933
K K + + +IQ+ + E ++ L QL++ EL R+ E EE A R
Sbjct: 1082 KLKKKDFEISQIQSKI----EDEQALGMQLQKKIKELQ--ARIEELEEEIEAERTSRAKA 1135
Query: 3934 AXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQG 4113
RL+ A A Q++ +++K EAE
Sbjct: 1136 EKHRADLSRELEEISERLEEAGGATAAQID------MNKKREAE---------------- 1173
Query: 4114 AGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELED 4284
+ RR EE+ Q LRKK+ L +Q++ + K+++ + K +++ E++D
Sbjct: 1174 FQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDD 1233
Query: 4285 SSMELENVRASHRDSEKRQKKFESQMAEERVAV---QKALLDRDAMSQELR-DRETRVLS 4452
+ +E+V + EK + E Q++E + Q+ + D +A L+ + T +
Sbjct: 1234 LASNMESVSKAKASLEKTCRALEDQLSEIKTKEEEHQRMINDLNAQRARLQTESGTNTMY 1293
Query: 4453 LLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQ 4632
L+ D ++ ++L +LQ I + + ELE+ +EAE
Sbjct: 1294 LVQRKDFEISQIQSKIEDEQALGMQLQKKIK---ELQARIEELEE---EIEAERTSRAKA 1347
Query: 4633 MEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELEN 4812
+ D + E+ RLE A ++ + NK EAE K RDLE E
Sbjct: 1348 EKHRADLSRELEEISERLEEAGGATAAQIE---MNKKREAE-----FQKMRRDLE---EA 1396
Query: 4813 EKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQA 4992
+ ++ A + RKK + EL +Q++ R+K++ + E +A
Sbjct: 1397 TLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMESVSKA 1456
Query: 4993 KEDIAALLREADRKFRAVEAEREQ------------LREANEGLMQARKQXXXXXXXXXX 5136
K ++ + R + + ++ + EQ R E +R+
Sbjct: 1457 KANLEKMCRTLEDQLSEIKTKEEQNQRMINDLNTQRARLQTETGEYSRQAEEKDALISQL 1516
Query: 5137 XRAKGGGIS--SEEKRRLEAKIAQXXXXXXXXQS---NCEL---AIDKQRKAQVQLEQIT 5292
R K G E KR LE +I QS +CEL +++++A+ +L++
Sbjct: 1517 SRGKQGFTQQIEELKRHLEEEIKAKNALAHALQSARHDCELLREQYEEEQEAKGELQRAL 1576
Query: 5293 TDLSMERTLNQKTEAEKQSLERSN--RDYKAKITELESGAQSR---ARAQMAALEAKVQY 5457
+ + E +T+ E +++R+ + K K+ + A+ A+ A+LE Q
Sbjct: 1577 SKANSE-VAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQR 1635
Query: 5458 LEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQ 5637
L++++ + +N A L+K+ + + + K+ E+ + LE S ++R+L +
Sbjct: 1636 LQNEVEDLMVDVERSNAACAALDKKQKNFDKILAEWKQKYEETQTELEASQKESRSLSTE 1695
Query: 5638 L-------DEAEDEMSRERTKHRNVQREADDLLD 5718
L +E+ D + + +++N+Q+E DL +
Sbjct: 1696 LFKMKNAYEESLDHLETLKRENKNLQQEIADLTE 1729
Score = 116 bits (290), Expect = 8e-24
Identities = 143/744 (19%), Positives = 305/744 (40%), Gaps = 22/744 (2%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A + E+ +++ + + +R +LE++ QE+ D+ ++ S AD ++
Sbjct: 849 EKEMANMKEEFEKTKEELAKSEAKRKELEEKMVVLLQEKNDLQLQVQAEADSLADAEERC 908
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ + +E L + + DE L + ++ E A ++
Sbjct: 909 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 968
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ T K+ N+ + DE A L ++++A +
Sbjct: 969 KE---------------KHATENKVKNLTEEMAVLDETIAKLTKEKKA----------LQ 1003
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
A Q + + E+ VN L + + K + V+ L+ LE+ + + + ++K+K++ +L
Sbjct: 1004 EAHQQTLDDLQVEEDKVNT-LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDL 1062
Query: 4279 E---DSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL 4449
+ DS M+LEN + D + ++K FE + ++ ++AL + +++++ + R+
Sbjct: 1063 KLAHDSIMDLENDK-QQLDEKLKKKDFEISQIQSKIEDEQAL--GMQLQKKIKELQARIE 1119
Query: 4450 SLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRV 4629
L E++ + ++++ R L +EL++ ++ G + EAE MR
Sbjct: 1120 ELEEEIEAERTSRAKAEKHRADLSRELEEISERLEEAGGATAAQIDMNKKREAEFQKMRR 1179
Query: 4630 QMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELE 4809
+EE + A + + A E + + E+++ L +I DL + +E
Sbjct: 1180 DLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNME 1239
Query: 4810 NEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEE--------YXXXXXXXXXXXXEYQ 4965
+ + K+ + +E+Q+ E++ + E R+ +
Sbjct: 1240 SVSKAKASLEKTCRALEDQLSEIKTKEEEHQRMINDLNAQRARLQTESGTNTMYLVQRKD 1299
Query: 4966 IECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRA 5145
E + + ED AL + +K + ++A E+L E E RA
Sbjct: 1300 FEISQIQSKIEDEQALGMQLQKKIKELQARIEELEEEIE--------------AERTSRA 1345
Query: 5146 KGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQ 5325
K ++ R LE +I++ + ++ ++K+R+A+ Q M R L +
Sbjct: 1346 KAEKHRADLSRELE-EISERLEEAGGATA-AQIEMNKKREAEFQ--------KMRRDLEE 1395
Query: 5326 KT---EAEKQSLERSNRDYKAKITE-LESGAQSRARAQMAALEAKVQYLEDQLNVEGQEK 5493
T EA +L + + D A++ E +++ + + + + E K++ + N+E K
Sbjct: 1396 ATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMESVSK 1455
Query: 5494 TAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRER 5673
AN LEK Q + K EQ + ++ N + L+ + E + +
Sbjct: 1456 AKAN-----LEKMCRTLEDQLSEIKTKEEQNQRMINDLNTQRARLQTETGEYSRQAEEKD 1510
Query: 5674 TKHRNVQREADDLLDANEQLTREL 5745
+ R E+L R L
Sbjct: 1511 ALISQLSRGKQGFTQQIEELKRHL 1534
>gi|3986196|dbj|BAA34955.1| myosin heavy chain [Dugesia japonica]
Length = 1743
Score = 973 bits (2516), Expect = 0.0
Identities = 561/1723 (32%), Positives = 956/1723 (54%), Gaps = 26/1723 (1%)
Frame = +1
Query: 655 GELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRV 834
G LE Q++QANP+LEA+GN+KT +N+NSSRFGKFIRI+F SG I+GA+IEFYLLEKSRV
Sbjct: 10 GTLEDQIVQANPVLEAYGNAKTTRNNNSSRFGKFIRIHFGTSGKIAGADIEFYLLEKSRV 69
Query: 835 LRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRF-LVNRG-ITLPNVDDVQEFHST 1008
+ Q + ER++HIFYQ+L K E LL D F +N+G +T+ VDD +E T
Sbjct: 70 ISQQKGERNYHIFYQLL-SAGGKSYHEKLLVTADPALFSFINQGELTIDGVDDEEEMKLT 128
Query: 1009 INSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPV 1188
+ ++GF+D+E S+ + ++++ +G ++F Q + +QA +KV LLG+
Sbjct: 129 DEAFGVLGFSDEERMSLFKCTTSIMNMGEMKFKQRPREEQAEADGTAEAEKVSFLLGVNA 188
Query: 1189 IELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHR 1368
+L +A L+P++KVG E+V K Q+++Q +++ A+AK+ Y R+F WLV R+NK+LD T
Sbjct: 189 KDLMQAILKPKVKVGNEYVTKGQSKDQVLYSLGALAKSLYNRMFAWLVNRVNKTLD-TKV 247
Query: 1369 QGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFI 1548
+ FIG+LDIAGFEIFD N FEQICINYTNE+LQQ FN+ MF+LEQEEY++E I+W+FI
Sbjct: 248 KRQFFIGVLDIAGFEIFDFNGFEQICINYTNERLQQFFNHHMFVLEQEEYKKEAIDWEFI 307
Query: 1549 DFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPKFIVPDM--- 1716
DFG+DLQ I+LIEKPMG+L++L+EEC+FPKA+D++ KL H K P F P
Sbjct: 308 DFGMDLQACIELIEKPMGILSILEEECMFPKASDQTLKAKLYDNHLGKSPNFGKPKPPKP 367
Query: 1717 -RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGIC 1893
+++HF + HYAG V Y+ WL KN DPLNE VVGL+ S + V+ ++ AE
Sbjct: 368 GHAEAHFELHHYAGSVPYNITGWLEKNKDPLNETVVGLLGASKETLVSSLFAPAE----- 422
Query: 1894 AAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINS 2073
+ + G R + G +T+S H+E L KLM L +TSPHF+RCI+PN K+ G +++
Sbjct: 423 ----DPSQSGKRKKGGAMQTISSTHRESLNKLMKNLMSTSPHFIRCIVPNEFKQPGVVDA 478
Query: 2074 NLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMIT 2253
+LV+ QL CNGVLEGIRICR+GFPNR+ + EF+ RY IL P+ IP+ F++GK K+++
Sbjct: 479 HLVMHQLHCNGVLEGIRICRKGFPNRMIYSEFKQRYSILAPNAIPQGFVEGKMVTDKILS 538
Query: 2254 ALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXX 2433
A+ +D NLYR+G +KVFF+ G LA LE+ RD KL++LI FQAQ RG+L RR Y
Sbjct: 539 AIQLDKNLYRLGNTKVFFKAGTLAQLEDLRDEKLSSLISMFQAQIRGYLMRRQYKRLQDQ 598
Query: 2434 XXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKME 2613
N YL LR W WW+LFTKVKP+L + R ++E++ +EL KE K E
Sbjct: 599 RVALSLIQRNIRKYLVLRTWTWWKLFTKVKPMLNIARQEEEMKKAAEELAKLKEEFEKSE 658
Query: 2614 HDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLS 2793
++ E++ ++ + + QLQ E ++ A+ ++ +L + ++E + ++ D+LS
Sbjct: 659 KYKKDLEEQNVTLLQAKNDLFLQLQTEQDSLADAEEKVSKLVLQKADMEGRIKELEDQLS 718
Query: 2794 XXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQD 2973
++K + + +K DQ ++
Sbjct: 719 EEENSATTLEEAKKKLNGEIEELKKDVESLESSLQKAEQEKAAKDQQIKTLNDNVREKEE 778
Query: 2974 AYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSE 3153
L EE+ + KAK +LE + E+E++L+RE++ +++
Sbjct: 779 QITKMQKEKKAADELQKKTEESLRAEEEKVSNLNKAKAKLEQAVDEMEENLSREQKVRAD 838
Query: 3154 LEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQ 3333
+E+ KRK+ EL+ +++ L + EL QL +++ EL ++ ++E+ V +Q++
Sbjct: 839 VEKAKRKVEGELKQNQEMLNDLERVKSELEEQLKRKEMELNGANSKIEDENNLVATLQRK 898
Query: 3334 MRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ-DLMSR 3510
++++Q I EL ED+E ER AR KAE + ++ A++E+V + L++ AT Q DL +
Sbjct: 899 IKELQARIQELEEDLEAERQARAKAEKAKHQLEAEIEEVT-ERLEEQGGATQAQTDLNKK 957
Query: 3511 KDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQ 3690
++ E+ KR +E+ E I + + K E DQ++Q +K +S++E+++N+
Sbjct: 958 REAELMKLKRDLEEANMQHEQAIMQTRKKQQDTANEFADQLDQLQKSKSKIEREKNELRG 1017
Query: 3691 ERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDH 3870
+ D++ ++ L ++ +++K K EA + E+Q L E + + R++ E
Sbjct: 1018 DIEDLSGQLESLNKAKINLEKSNKGLEATISELQNKLDELTKQLSDAGNSNNRNQHENSE 1077
Query: 3871 LNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLK----------IANINRARQ- 4017
L++ E+ E + + +R K +++++ R+
Sbjct: 1078 LHKSLEDAESQINQLSKAKQQLQAQLEEAKQNLEDESRAKSKLNGDLRNALSDLDAMRES 1137
Query: 4018 LEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVE 4197
LE+E+ D + + ++ L+ ++ + QG G R ++++EE ++K ++
Sbjct: 1138 LEEEQEGKSDVQRQLVKVQNELQ-QLKSNSQGTGGVR-------SEEMEEFKRKMNARIQ 1189
Query: 4198 HLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERV 4377
L+++ E ++ ++ + K ++Q E+ED +++E EK+QK + + E +
Sbjct: 1190 ELEEESESNKSKCSQLEKVKSRLQGEIEDLLIDVERANGLASQLEKKQKGVDKLIGEWQK 1249
Query: 4378 AVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDD 4557
++ + + +E R V L + ++ ++ +E R ++L E+ D +
Sbjct: 1250 KYSESQQELEVSLRESRTVSAEVFKLKSVLENSQDQIESLKRENKNLSDEIHDLTEQLGE 1309
Query: 4558 FGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISN 4737
G+NVHE+EKA++ +E E ++++ +EE E L+ E R ++ + E++R I+
Sbjct: 1310 GGRNVHEIEKARKRIEIERDELQHALEEAESALEQEEAKSQRAQLEISQARQEAERRIAE 1369
Query: 4738 KDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEE 4917
K+ E E R+ + + ++ LE E RG++ A+ +KK+E+ I ELE L+ ANRLK E
Sbjct: 1370 KEEEFEVTRKNHQRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSE 1429
Query: 4918 YXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQA 5097
E Q + +E +E ++ L A+RK + E E++R + A
Sbjct: 1430 QEKNSKKYQQQLLEMQAQVDEQHHQRELVSEQLVLAERKLTMMNGELEEVRNMCD---HA 1486
Query: 5098 RKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQ 5277
K K +S + + AK + Q++ E A ++ R+A Q
Sbjct: 1487 EKNRKAAESEKNEAVDKLNELSIQNSSFMAAK-RKLETDLSAMQADLEEATNEGRQANEQ 1545
Query: 5278 LEQITTD-------LSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAA 5436
L++ D + E+ Q+ E +++ E +D + K+ E E+ A + ++
Sbjct: 1546 LKKAIFDNTRLFDEIKQEQEHAQQAEKARKNFESQLKDLQTKLDEAEANALKGGKKALSK 1605
Query: 5437 LEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLK 5616
LE +++ LE +L+ E + + AR+ ++RL + T Q +++K+ ++ ++L+E K
Sbjct: 1606 LEQRIRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAK 1665
Query: 5617 NRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
+ +RQ++EAE+ + K+R +Q+E +D + +Q + L
Sbjct: 1666 IKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQAL 1708
Score = 116 bits (290), Expect = 8e-24
Identities = 133/725 (18%), Positives = 298/725 (40%), Gaps = 36/725 (4%)
Frame = +1
Query: 2533 QVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAE 2712
++ R +E+R ++L E L K + + ++ K L+ I E +Q +L + ++ ++
Sbjct: 1007 KIEREKNELRGDIEDLSGQLESLNKAKINLEKSNKGLEATISE---LQNKLDELTKQLSD 1063
Query: 2713 LDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXX 2892
+ R Q N EL + D +++ + + + D
Sbjct: 1064 AGNSNNRNQHENSELHKSLEDAESQINQLSKAKQQLQAQLEEAKQNLEDESRAKSKLNGD 1123
Query: 2893 XXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHG 3072
D + + Q G + E K
Sbjct: 1124 LRNALSDLDAMRESLEEEQEGKSDVQRQLVKVQNELQQLKSNSQGTGGVRSEEMEEFKRK 1183
Query: 3073 VKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQL 3252
+ A+ + ELE++ + S+LE+ K +L E+ED + G +L +
Sbjct: 1184 MNAR------IQELEEESESNKSKCSQLEKVKSRLQGEIEDLLIDVERANGLASQLEKKQ 1237
Query: 3253 MKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREV- 3429
D+ + +Y E + + ++ R + + +L+ +E N++++ E +RE
Sbjct: 1238 KGVDKLIGEWQKKYSESQQELEVSLRESRTVSAEVFKLKSVLE---NSQDQIESLKRENK 1294
Query: 3430 -------------------VAQLEKVKGDVLDKVDEAT-MLQDLMSRKDEEVNATKRA-- 3543
V ++EK + + + DE L++ S ++E ++RA
Sbjct: 1295 NLSDEIHDLTEQLGEGGRNVHEIEKARKRIEIERDELQHALEEAESALEQEEAKSQRAQL 1354
Query: 3544 -IEQIQHTMEGKIEEQKAKFS-------RQVEELHDQIEQHKKQRSQLEKQQNQADQERA 3699
I Q + E +I E++ +F R +E + +E + R++ K + + + +
Sbjct: 1355 EISQARQEAERRIAEKEEEFEVTRKNHQRSLESMQASLEAEVRGRTEAMKMKKKLEHDIN 1414
Query: 3700 DMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNR 3879
++ + +++ +K K ++ L+E+QA + E + + +QL + +L +N
Sbjct: 1415 ELEVGLDTANRLKSEQEKNSKKYQQQLLEMQAQVDEQHHQRELVSEQLVLAERKLTMMNG 1474
Query: 3880 VREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEE 4059
EE + + ++ A + + + R+LE + +A+ + EE
Sbjct: 1475 ELEEVRNMCDHAEKNRKAAESEKNEAVDKLNELSIQNSSFMAAKRKLETDLSAMQADLEE 1534
Query: 4060 A--EGLRAH--LEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESE 4227
A EG +A+ L+K I + E +++ E + QQ E+ RK ++ LQ +L+E+E
Sbjct: 1535 ATNEGRQANEQLKKAIFDNTRLFDEIKQEQEHA--QQAEKARKNFESQLKDLQTKLDEAE 1592
Query: 4228 V-AKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDR 4404
A + ++ K++Q + + EL+ + H +++K +K + ++ E + + ++
Sbjct: 1593 ANALKGGKKALSKLEQRIRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQ 1652
Query: 4405 DAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELE 4584
D M Q + + + ++ + +V+ +E + R +QQE++DS D + + +L
Sbjct: 1653 DRMQQLIENLQAKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLR 1712
Query: 4585 KAKRS 4599
RS
Sbjct: 1713 AKNRS 1717
>gi|12697534|emb|CAC28360.1| myosin heavy chain [Toxocara canis]
Length = 1814
Score = 971 bits (2509), Expect = 0.0
Identities = 581/1786 (32%), Positives = 961/1786 (53%), Gaps = 20/1786 (1%)
Frame = +1
Query: 412 KKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRN 591
K+R EMPPH+FA++D AYR+MLQ E+ S+L TGESGAGKTENTKKVI Y A V GA++
Sbjct: 1 KRRTEMPPHLFAVSDEAYRNMLQFHENLSMLITGESGAGKTENTKKVIAYFA-VVGASQG 59
Query: 592 KSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINF 771
K ++ + LE Q++Q NP+LEAFGN+KTV+N+NSSRFGKFIRI+F
Sbjct: 60 KG---TGEKKVT-----------LEDQIIQTNPLLEAFGNAKTVRNNNSSRFGKFIRIHF 105
Query: 772 DMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEG-VDNYRF 948
+G ++ +IE YLLEKSRV+RQA ER +HIFYQ+ K + LL+ + +Y F
Sbjct: 106 SRAGKVASCDIEHYLLEKSRVIRQAPGERCYHIFYQLYSDYIPTLKKDLLLDAPLKDYWF 165
Query: 949 LVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQ 1128
+ +T+ V+D +E T + I+ F+ +E + R+VSA++ +GN++F Q + +Q
Sbjct: 166 VAQAELTIEGVNDKEEHQLTDEAFDILNFSAEEKMNCYRLVSAIMHMGNMKFKQRPREEQ 225
Query: 1129 AMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASY 1308
A +K ++ G+ E K+ +PR+KVG E+VNK QN +Q +AV A+AK Y
Sbjct: 226 AEPDGTDEAEKSANMFGVDSEEFLKSLTKPRVKVGTEWVNKGQNVDQVTWAVGAMAKGIY 285
Query: 1309 ERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNN 1488
RLF WLV + N +LD+ FIG+LDIAGFEIFD NSFEQ+ IN+ NEKLQQ FN+
Sbjct: 286 ARLFHWLVKKCNLTLDQKGIPRDYFIGVLDIAGFEIFDFNSFEQLWINFVNEKLQQFFNH 345
Query: 1489 TMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEK 1668
MF+LEQEEY+REGI+W FIDFGLDLQ I+LIEKPMG++++LDEEC+ PKA D + +K
Sbjct: 346 HMFVLEQEEYEREGIQWTFIDFGLDLQACIELIEKPMGIISMLDEECIVPKATDMTLAQK 405
Query: 1669 LQKTH-NKHPKFIVP----DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQ 1833
L H KHP F P S++HFA+ HYAG V Y+ WL KN DPLN+ V ++
Sbjct: 406 LIDNHLGKHPNFEKPKPPKGKPSEAHFAMKHYAGTVRYNVTNWLEKNKDPLNDTFVACLK 465
Query: 1834 NST-DPFVAGIWKDAEFAGICAAEMNETAFGMRSRK-GMFRTVSQLHKEQLTKLMTTLRN 2007
S + + W+D A + E G + K G F TVS +++E L LM+ L
Sbjct: 466 ASKGNALLNDCWQDYTTQEEAAVQAKEGGGGKKKGKSGSFMTVSMMYRESLNNLMSMLNK 525
Query: 2008 TSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEI 2187
T PHF+RCIIPN +KKSG +++ LVL QL CNGVLEGIRICR+GFPNR ++F+HRY +
Sbjct: 526 THPHFIRCIIPNEKKKSGLLDAALVLNQLTCNGVLEGIRICRKGFPNRSLHEDFKHRYAM 585
Query: 2188 LTPDVIPKNFIDGKESVRKMITALDIDTNL----YRIGQSKVFFRTGVLAHLEEERDLKL 2355
L K+ D K+ +++ L D + +R+G++KVFF+ G++AHLE+ RD KL
Sbjct: 586 LASKE-AKSDPDPKKCAEAILSRLVNDGAITEEHFRVGKTKVFFKAGIVAHLEDLRDQKL 644
Query: 2356 TALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQ 2535
++ FQAQ R F+ N A+ LR W W+ L+ K+KP+L+
Sbjct: 645 GEILAGFQAQIRWFVMMLDRHRRAKQRAGYVILQRNVRAWSILRTWDWYLLYGKIKPMLK 704
Query: 2536 VTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAEL 2715
+ +E+ +D+++ + ++ + E + E+ +++ E+ + +L++ ++
Sbjct: 705 GGKEQEEMDKMNDQIKQLEAKIAEEEKARKGLEESSTKLLEEKNAVFGELEEAKGKLSDA 764
Query: 2716 DDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXX 2895
+D RL T +++ +N++ DRL ++K +
Sbjct: 765 EDRLNRLNTLRNDIDKQINELNDRLGDQEDRNADLMRAKKKVETDAENLRKTIEELEGRL 824
Query: 2896 XXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV 3075
DK DQ + L L E++ H
Sbjct: 825 QKAETDKQAKDQQIRTLQDEMQLQDENIAKLNKEKKHQEEINRKLMEDLQSEEDKGNHTN 884
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLM 3255
K KG+LE L +LE L RE++ ++++E+ KRK+ EL+ +++++ E + E+ + L
Sbjct: 885 KLKGKLEQSLDDLEDSLEREKRARNDIEKQKRKVEGELKVAQENIDEINRQRHEIESNLK 944
Query: 3256 KRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVA 3435
K++ E Q TR +EE V ++KQ+++ Q I E+ E++E ER +R KA+ + ++
Sbjct: 945 KKEAESQAVATRLEEEQDLVNKLKKQLKETQGRIGEVEEELENERQSRAKADRVKSDLQR 1004
Query: 3436 QLEKVKGDVLDKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQV 3612
+LE++ GD LD+ AT Q +L ++ E+ +R +E+ E ++ + K + V
Sbjct: 1005 ELEEL-GDRLDEQGGATAAQVELNKKRGAELAKLRRDLEEANMNHENQLAAIRKKHNDAV 1063
Query: 3613 EELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQ 3792
EL DQIEQ +KQ++++EK + QA ++ D+A +I A+R + +K K +E + E+Q
Sbjct: 1064 AELGDQIEQAQKQKAKVEKDKAQAQRDAEDLANQIETETAARVNSEKLAKQYEMQIAELQ 1123
Query: 3793 ANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXX 3972
E + + R + LNR EE E + R
Sbjct: 1124 TKCDEQNRQLQEFTSLKSRMTGDNADLNRQIEEAESQLNALTRLKGQLTSQLEEARQSLD 1183
Query: 3973 XXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEES-- 4146
R + +A+ + E + + + EE ++ + K++ A + + K E
Sbjct: 1184 EEARERNTLAAQAKNYQHEIDQIRESMEEEIEAKSEILKQLSHANAEIQQWQTKFESEGL 1243
Query: 4147 -VNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHR 4323
+L+E +K+ L+ + LQ+ L+ + + ++K ++ +L+D+ +++E A
Sbjct: 1244 LKADELDEAKKRQLQKINELQEALDAANSKITSLEKTKSRLVSDLDDAQVDVERANAYAN 1303
Query: 4324 DSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDR 4503
EK+QK F+ + E R + D +E R+ T ++ L E D + E +E R
Sbjct: 1304 QLEKKQKGFDKVLDEWRKKTDDLAAELDNAQREARNVSTELMKLKTEQDEILETIEGLRR 1363
Query: 4504 VRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLR 4683
+SL QE++D + G++V E++K R LE E ++++ ++E E L+ E LR
Sbjct: 1364 ENKSLTQEIKDLTDQLSEGGRSVFEMQKIIRRLEVEKDELQHALDEAEAALEAEESKVLR 1423
Query: 4684 LEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIEN 4863
+V ++SE ++ I K+ E E R+ + I ++ LENE +GK+ + +KK+E+
Sbjct: 1424 AQVEVSQIRSEIEKRIQEKEEEFENTRKNHQRAIESMQASLENETKGKADLLRLKKKLES 1483
Query: 4864 QIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRA 5043
I ELE L+ AN + E Q + E ++++EDI +++
Sbjct: 1484 DINELEIALDHANLANADAQKNLKKYQDQIRELQQQVEIEQRSREDIREQYLNMEKRATV 1543
Query: 5044 VEAEREQLREANEGLMQARKQXXXXXXXX----XXXRAKGGGISSEEKRRLEAKIAQXXX 5211
+++E+E+L A + +ARKQ A+ ++S KR+L+ ++ Q
Sbjct: 1544 LQSEKEELVVAMDQAERARKQAERDANEAHVQCNELAAQAESLNS-IKRKLDGELLQIQT 1602
Query: 5212 XXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITE 5391
+ + ++ + A ++ L E+ ++E ++SLE ++ +A++ E
Sbjct: 1603 DLDETLNEYRSSEERSKAAMADAARLAEQLHQEQENAMQSERMRKSLETQLKEMQARLDE 1662
Query: 5392 LESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKR 5571
E+ A + +A LE +++ LE +L+ E + N+ + ++R+ + Q +++K+
Sbjct: 1663 AEAAALKGGKKVIAKLETRIRELESELDGEQRRYKETNKTLSKHDRRIRELQFQVDEDKK 1722
Query: 5572 ANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
E+ +L++K K + ++Q++EAE+ + K R +Q + DD
Sbjct: 1723 NAERTHDLIDKLQNKLKAQKKQIEEAEELANLNLQKFRQIQHQLDD 1768
Score = 127 bits (320), Expect = 2e-27
Identities = 150/742 (20%), Positives = 303/742 (40%), Gaps = 18/742 (2%)
Frame = +1
Query: 3571 GKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADID 3750
GK +E+ K + Q+++L +I + +K R LE+ + +E+ + E+ + +D +
Sbjct: 706 GKEQEEMDKMNDQIKQLEAKIAEEEKARKGLEESSTKLLEEKNAVFGELEEAKGKLSDAE 765
Query: 3751 KKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLA 3930
+ L + + D+ L D+L D L R +++ E N+++ +
Sbjct: 766 DR-------LNRLNTLRNDIDKQINELNDRLGDQEDRNADLMRAKKKVETDAENLRKTIE 818
Query: 3931 TAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLD-EKEEAEGLRAHLEKEIHAAR 4107
+ +I + QL+DE A L+ EK+ E + L +++
Sbjct: 819 ELEGRLQKAETDKQAKDQ-QIRTLQDEMQLQDENIAKLNKEKKHQEEINRKLMEDL---- 873
Query: 4108 QGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDS 4287
++EE +L+ K + ++ L+ LE + A+ I + K+K++ EL+ +
Sbjct: 874 --------QSEEDKGNHTNKLKGKLEQSLDDLEDSLEREKRARNDIEKQKRKVEGELKVA 925
Query: 4288 SMELENVRASHRDSEK--RQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLN 4461
++ + + E ++K+ ESQ R+ ++ L+++ + ++L++ + R+ +
Sbjct: 926 QENIDEINRQRHEIESNLKKKEAESQAVATRLEEEQDLVNK--LKKQLKETQGRIGEVEE 983
Query: 4462 EVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE 4641
E++ ++ ++DRV+ LQ+EL++ D+ G + + AEL +R +EE
Sbjct: 984 ELENERQSRAKADRVKSDLQRELEELGDRLDEQGGATAAQVELNKKRGAELAKLRRDLEE 1043
Query: 4642 LEDNLQ-------------IAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQ 4782
N + +AE + Q K E D+A + +D E
Sbjct: 1044 ANMNHENQLAAIRKKHNDAVAELGDQIEQAQKQKAKVEKDKAQAQRDAE----------- 1092
Query: 4783 IRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEY 4962
DL N++E E + + K+ E QI EL+ + + NR +E+ +
Sbjct: 1093 --DLANQIETETAARVNSEKLAKQYEMQIAELQTKCDEQNRQLQEFTSLKSRMTGDNADL 1150
Query: 4963 QIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXR 5142
+ EEA + L + QL EA + L + ++ +
Sbjct: 1151 NRQIEEAESQLNALTRLKGQLT----------SQLEEARQSLDEEARERNTLAAQAKNYQ 1200
Query: 5143 AKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTL- 5319
+ I + +EAK + + A +++Q T E L
Sbjct: 1201 HEIDQIRESMEEEIEAKSE---------------ILKQLSHANAEIQQWQTKFESEGLLK 1245
Query: 5320 -NQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKT 5496
++ EA+K+ L+ KI EL+ A A +++ +LE L L+ +
Sbjct: 1246 ADELDEAKKRQLQ--------KINELQE-ALDAANSKITSLEKTKSRLVSDLDDAQVDVE 1296
Query: 5497 AANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERT 5676
AN A +LEK+ + ++L++ K +L +LD A+ E T
Sbjct: 1297 RANAYANQLEKK--------------QKGFDKVLDEWRKKTDDLAAELDNAQREARNVST 1342
Query: 5677 KHRNVQREADDLLDANEQLTRE 5742
+ ++ E D++L+ E L RE
Sbjct: 1343 ELMKLKTEQDEILETIEGLRRE 1364
Score = 83.2 bits (204), Expect = 7e-14
Identities = 110/481 (22%), Positives = 205/481 (41%), Gaps = 42/481 (8%)
Frame = +1
Query: 3043 LDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAE-- 3216
LD+ +R V +L +L+ + + + L + + L E++D D L+E
Sbjct: 1330 LDNAQREARNVST------ELMKLKTEQDEILETIEGLRRENKSLTQEIKDLTDQLSEGG 1383
Query: 3217 -KMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETE-R 3390
+ +++++ +L +ELQH L DE A + + ++ Q + ++R ++E +
Sbjct: 1384 RSVFEMQKIIRRLEVEKDELQHAL---DEAEAALEAEESKVLRAQVEVSQIRSEIEKRIQ 1440
Query: 3391 NARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTME 3570
+ E TR+ +E ++ + ++ L L + + ++N + A++ H
Sbjct: 1441 EKEEEFENTRKNHQRAIESMQASLENETKGKADLLRLKKKLESDINELEIALD---HANL 1497
Query: 3571 GKIEEQK--AKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQE-----IALLQ 3729
+ QK K+ Q+ EL Q+E ++ R + +Q ++ + E +A+ Q
Sbjct: 1498 ANADAQKNLKKYQDQIRELQQQVEIEQRSREDIREQYLNMEKRATVLQSEKEELVVAMDQ 1557
Query: 3730 ASRADIDKKRKIHEAHLM--EIQANLAESDEHKRTLIDQLERSRDELDH-LNRVREEEEH 3900
A RA +R +EAH+ E+ A + KR L +L + + +LD LN R EE
Sbjct: 1558 AERARKQAERDANEAHVQCNELAAQAESLNSIKRKLDGELLQIQTDLDETLNEYRSSEER 1617
Query: 3901 AFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEA-----E 4065
+ A M A A + + + QL+ E A LDE E A +
Sbjct: 1618 SKAAM----ADAARLAEQLHQEQENAMQSERMRKSLETQLK-EMQARLDEAEAAALKGGK 1672
Query: 4066 GLRAHLEKEIHAARQGA-GEARRKAEESV-----NQQLEELR------KKNLRDVEHL-- 4203
+ A LE I GE RR E + ++++ EL+ KKN L
Sbjct: 1673 KVIAKLETRIRELESELDGEQRRYKETNKTLSKHDRRIRELQFQVDEDKKNAERTHDLID 1732
Query: 4204 ---------QKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFES 4356
+KQ+EE+E LQ ++IQ +L+D+ RA H ++ + + +S
Sbjct: 1733 KLQNKLKAQKKQIEEAEELANLNLQKFRQIQHQLDDA-----EERADHAENSLSKMRAKS 1787
Query: 4357 Q 4359
+
Sbjct: 1788 R 1788
Score = 64.3 bits (155), Expect = 3e-08
Identities = 92/427 (21%), Positives = 185/427 (42%), Gaps = 6/427 (1%)
Frame = +1
Query: 4489 EESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAE 4668
EE D++ ++Q L+ I+ ++ K LE++ L E N + ++EE + L AE
Sbjct: 710 EEMDKMNDQIKQ-LEAKIAEEEKARKG---LEESSTKLLEEKNAVFGELEEAKGKLSDAE 765
Query: 4669 DARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHR 4848
D RL + + + ++++ + E++ L++ + +E + EN R
Sbjct: 766 DRLNRLNTLRNDIDKQINE-LNDRLGDQEDRNADLMRAKKKVETDAENL----------R 814
Query: 4849 KKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREAD 5028
K IE G L Q+ E + K++ E + + ++ +E+I L E
Sbjct: 815 KTIEELEGRL-QKAETDKQAKDQQIRTLQDEMQLQDENIAKLNKEKKHQEEINRKLMED- 872
Query: 5029 RKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRL---EAKIA 5199
+++E ++ N+ ++ + + R K E+++R E K+A
Sbjct: 873 -----LQSEEDKGNHTNK--LKGKLEQSLDDLEDSLEREKRARNDIEKQKRKVEGELKVA 925
Query: 5200 QXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKA 5379
Q Q + E+ + ++K + + + + T L E+ L K + KQ E R +
Sbjct: 926 QENIDEINRQRH-EIESNLKKK-EAESQAVATRLEEEQDLVNKLK--KQLKETQGRIGEV 981
Query: 5380 KITELESGAQSRARAQMAA--LEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQ 5553
+ ELE+ QSRA+A L+ +++ L D+L+ +G A ++ L +
Sbjct: 982 E-EELENERQSRAKADRVKSDLQRELEELGDRLDEQGGATAAQVELNKKRGAELAKLRRD 1040
Query: 5554 FEDEKRANE-QAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQ 5730
E+ +E Q + +K N L Q+++A+ + ++ QR+A+DL + E
Sbjct: 1041 LEEANMNHENQLAAIRKKHNDAVAELGDQIEQAQKQKAKVEKDKAQAQRDAEDLANQIET 1100
Query: 5731 LTRELMN 5751
T +N
Sbjct: 1101 ETAARVN 1107
>gi|50757923|ref|XP_425360.1| PREDICTED: similar to fast myosin heavy
chain HCII [Gallus gallus]
Length = 1760
Score = 963 bits (2489), Expect = 0.0
Identities = 587/1718 (34%), Positives = 926/1718 (53%), Gaps = 56/1718 (3%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V E F+ G+I+ +V V+ + +T+ D V NPPK+DKIEDM+ +T+L
Sbjct: 40 FVAHPKESFVKGTIQSRETGKVTVK-TEGGETLTVKEDQVFSMNPPKYDKIEDMAMMTHL 98
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 99 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVLAYRGKKRQEAPPHIFS 158
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A + K + +
Sbjct: 159 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAASGEKKKEEQSGKMQ-- 216
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 217 ---------GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIE 267
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPNV 981
YLLEKSRV Q + ERS+HIFYQ+ E E LL + +Y F+ IT+P++
Sbjct: 268 TYLLEKSRVTFQLKAERSYHIFYQVTSN-KKPELIEMLLITTNPYDYPFVSQGEITVPSI 326
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
DD +E +T +++ I+GF DE ++I ++ AV+ GNL+F Q+++ +QA V K
Sbjct: 327 DDKEELMATDSAIDILGFTADEKTAIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADK 386
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L+GL ++ KA PR+KVG E+V K Q +Q AV A+AKA YER+F W+V RI
Sbjct: 387 AAYLMGLNSADMLKALCYPRVKVGNEYVTKGQTVQQVHNAVGALAKAVYERMFLWMVVRI 446
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NSFEQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 447 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H K
Sbjct: 506 KEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSSN 565
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P + ++HF+++HYAG VDY+ WL KN DPLNE V+GL Q S+ +A ++
Sbjct: 566 FQKPKPTKGKVEAHFSLIHYAGTVDYNITGWLEKNKDPLNETVIGLYQKSSLKTLALLF- 624
Query: 1870 DAEFAGICA-AEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNH 2046
A + G A A G + + F+TVS L +E L KLMT LR+T PHFVRCIIPN
Sbjct: 625 -ANYGGAEAEASAGAGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNE 683
Query: 2047 EKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFID 2223
K G + LVL QLRCNGVLEGIRICR+GFPNRV + +F+ RY++L IP+ FID
Sbjct: 684 TKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPNRVLYADFKQRYKVLNASAIPEGQFID 743
Query: 2224 GKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLS 2403
K++ K++ ++DID Y+ G +KVFF+ G++ LEE RD KL LI QA+CRGFL
Sbjct: 744 SKKACEKLLGSIDIDHTQYKFGHTKVFFKAGLVGLLEEMRDEKLAQLITRTQARCRGFLM 803
Query: 2404 RRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELR 2583
R Y N A++ +++W W +LF K+KPLL+ ++ E+ E
Sbjct: 804 RVEYQKMVERRESVFCIQYNIRAFMNVKHWPWMKLFFKIKPLLKSAESEKEMANMKQEFE 863
Query: 2584 ATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEY 2763
TKE L K E +E E+K+ +++ E+ +Q Q+Q E++ A+ ++ +L +LE
Sbjct: 864 KTKEELAKSEAKRKELEEKMVKLVQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEA 923
Query: 2764 IVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXX 2943
V ++ +R +RK + + +K +
Sbjct: 924 KVKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 983
Query: 2944 XXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQD 3123
+ L E++ KAK +LE Q+ +LE
Sbjct: 984 LTEEMAALDETIVKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGS 1043
Query: 3124 LNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEE 3303
L +E++ + +LE+ KRKL +L+ + D + + ++L+ +L K+D E+ ++ ++E
Sbjct: 1044 LEQEKKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEISQIQSKIEDE 1103
Query: 3304 SANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEA 3483
+QK+++++Q I+EL E++E ER +R KAE R ++ +LE++ G L++ A
Sbjct: 1104 QLLGMQLQKKIKELQARIEELEEEIEAERTSRAKAEKHRADLSRELEEISGR-LEEAGGA 1162
Query: 3484 TMLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQ 3660
T Q M++K E E +R +E+ E + K + EL +QI+ ++ + +
Sbjct: 1163 TAAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQK 1222
Query: 3661 LEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQ 3840
LEK++++ E D+A + + ++A+++K + E L E + ++ L Q
Sbjct: 1223 LEKEKSELKMEIDDLASNMESVSKAKANLEKMCRTLEDQLSEFKTKDEQNQRMISDLSAQ 1282
Query: 3841 LERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQL 4020
R + E R +E++ + + R + K A + +
Sbjct: 1283 RARLQTESGEYARQADEKDGLISQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHSLQSA 1342
Query: 4021 EDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN------ 4182
+ + L ++ EE + L++ + A + R K E Q+ EEL +
Sbjct: 1343 RHDCDLLREQYEEELEAKGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKYVGKVG 1402
Query: 4183 ---------------------------LRDVEHLQKQLEESEVAKERILQSKKKIQQELE 4281
++ L +Q+ E A + + KK+I+QE
Sbjct: 1403 KAGRKLLSPGPFPLYSVSYPCDFSLFPAEEISDLTEQIAEGGKAIHELEKVKKQIEQEKS 1462
Query: 4282 DSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL-SLL 4458
+ LE AS E + + + ++ + + + + + ++D +L+ R++ SL
Sbjct: 1463 EIQAALEEAEASLEHEEGKILRLQLELNQVKSEIDRKIAEKDEEIDQLKRNHLRIVESLQ 1522
Query: 4459 NEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQM- 4635
+ +D E+ R+++ ++ +L + + E +K R+ +A L D ++ +
Sbjct: 1523 SSLDAEIRSRNEALRLKKKMEGDLNEMEIQLSHANRVAAEAQKNLRNTQAVLKDTQIHLD 1582
Query: 4636 ------EELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEE-----KRRGLL-K 4779
E+L++ + + E L+ + L++ ++ +K V +E R LL
Sbjct: 1583 DALRTQEDLKEQVAMVERKTNLLQAEIEDLRAPLEQTNPSKKVAEQELMDAVNRVHLLHT 1642
Query: 4780 QIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXE 4959
Q+R+LE E++ E++ + AV +K E ++ EL Q EE +
Sbjct: 1643 QVRELEGEVDAEQKRSAEAVKGVRKYERRVKELTYQ-------SEEDRKNILRLQDLVDK 1695
Query: 4960 YQIECEEARQAKEDIAALLREADRKFRAVEAEREQLRE 5073
Q++ + ++ E+ L KFR ++ E E+ E
Sbjct: 1696 LQMKVKSYKRQSEEAEELSNVNLSKFRKIQHELEEAEE 1733
Score = 207 bits (526), Expect = 3e-51
Identities = 200/874 (22%), Positives = 383/874 (42%), Gaps = 60/874 (6%)
Frame = +1
Query: 3040 LLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKL-------------- 3177
L D EER +K K +LE ++ E+ + E + +EL KRKL
Sbjct: 904 LADAEERCDQLIKTKIQLEAKVKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL 963
Query: 3178 ---LAELEDSKD-------HLAEKMGKVEELNNQLMKRDEELQ--HQLTRYD--EESANV 3315
LA++E K +L E+M ++E +L K + LQ HQ T D E V
Sbjct: 964 ELTLAKVEKEKHATENKVKNLTEEMAALDETIVKLTKEKKALQEAHQQTLDDLQAEEDKV 1023
Query: 3316 TLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ 3495
+ K ++ +D+L +E E+ R E +R++ L+ ++D ++ L
Sbjct: 1024 NTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLD 1083
Query: 3496 DLMSRKDEEVNATKRAIEQIQ---HTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLE 3666
+ + +KD E++ + IE Q ++ KI+E +A+ +EEL ++IE + R++ E
Sbjct: 1084 EKLKKKDFEISQIQSKIEDEQLLGMQLQKKIKELQAR----IEELEEEIEAERTSRAKAE 1139
Query: 3667 KQQNQADQERADMA---QEIALLQASRADIDKKRKIHEAHLMEIQANLAESD-EHKRTLI 3834
K + +E +++ +E A++ +++KKR EA +++ +L E+ +H+ T
Sbjct: 1140 KHRADLSRELEEISGRLEEAGGATAAQIEMNKKR---EAEFQKMRRDLEEATLQHEATAA 1196
Query: 3835 -------DQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKI 3993
D +++D+L RV+++ E + ++ + ++
Sbjct: 1197 ALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMESVSKAKANLEKM-- 1254
Query: 3994 ANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEES--VNQQLEE 4167
R LED+ + + E+ + + + L + + +GE R+A+E + QL
Sbjct: 1255 -----CRTLEDQLSEFKTKDEQNQRMISDLSAQRARLQTESGEYARQADEKDGLISQLSR 1309
Query: 4168 LRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKK 4347
++ + +E L++QLEE AK + S + + + + + E + + ++ K
Sbjct: 1310 GKQAFTQQIEELKRQLEEEIKAKNALAHSLQSARHDCDLLREQYEEELEAKGELQRALSK 1369
Query: 4348 FESQMAEERVAVQKALLDRDAMSQELR-----DRETRVLSLLNEVDIMKEHLEESDRVRR 4512
S++A+ R + + R +E + + R LL+ +
Sbjct: 1370 ANSEVAQWRTKYETDAIQRTEELEEAKYVGKVGKAGR--KLLSPGPFPLYSVSYPCDFSL 1427
Query: 4513 SLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEV 4692
+E+ D + GK +HELEK K+ +E E ++++ +EE E +L+ E LRL++
Sbjct: 1428 FPAEEISDLTEQIAEGGKAIHELEKVKKQIEQEKSEIQAALEEAEASLEHEEGKILRLQL 1487
Query: 4693 TNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIG 4872
+KSE DR I+ KD E ++ +R L+ + L++ L+ E R ++ A+ +KK+E +
Sbjct: 1488 ELNQVKSEIDRKIAEKDEEIDQLKRNHLRIVESLQSSLDAEIRSRNEALRLKKKMEGDLN 1547
Query: 4873 ELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEA 5052
E+E QL ANR+ E + QI ++A + +ED+ + +RK ++A
Sbjct: 1548 EMEIQLSHANRVAAEAQKNLRNTQAVLKDTQIHLDDALRTQEDLKEQVAMVERKTNLLQA 1607
Query: 5053 EREQLREANEGLMQARKQXXXXXXXX--------XXXRAKGGGISSEEKRRLEAKIAQXX 5208
E E LR E ++K R G + +E+KR EA +
Sbjct: 1608 EIEDLRAPLEQTNPSKKVAEQELMDAVNRVHLLHTQVRELEGEVDAEQKRSAEA--VKGV 1665
Query: 5209 XXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKIT 5388
++ RK ++L+ + L M+ ++ E + L N KI
Sbjct: 1666 RKYERRVKELTYQSEEDRKNILRLQDLVDKLQMKVKSYKRQSEEAEELSNVNLSKFRKIQ 1725
Query: 5389 ELESGAQSR---ARAQMAALEAKVQYLEDQLNVE 5481
A+ R A +Q+ L AK + ++ E
Sbjct: 1726 HELEEAEERADIAESQVNKLRAKSREFHRRIEEE 1759
Score = 155 bits (392), Expect = 1e-35
Identities = 195/940 (20%), Positives = 386/940 (40%), Gaps = 62/940 (6%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNN 3246
K ++ + + +++L + + ELE+ KL+ E D + + A+ + EE +
Sbjct: 853 KEMANMKQEFEKTKEELAKSEAKRKELEEKMVKLVQEKNDLQLQVQAEADALADAEERCD 912
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
QL+K +L+ ++ DEE N L K+ R ++ EL++D++ E
Sbjct: 913 QLIKTKIQLEAKVKEVTERAEDEEEINAELTAKK-RKLEDECSELKKDIDD-------LE 964
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E L + + + +E A + A +Q ++ +
Sbjct: 965 LTLAKVEKEKHATENKVKNLTEEMAALDETIVKLTKEKKALQEAHQQTLDDLQAEEDKVN 1024
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK 3753
+ + K K +QV++L +EQ KK R LE+ + + + + I L+ + +D+
Sbjct: 1025 TLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDE 1084
Query: 3754 KRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLAT 3933
K K + + +IQ+ + E ++ L QL++ EL R+ E EE A R
Sbjct: 1085 KLKKKDFEISQIQSKI----EDEQLLGMQLQKKIKELQA--RIEELEEEIEAERTSRAKA 1138
Query: 3934 AXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQG 4113
RL+ A A Q+E +++K EAE +
Sbjct: 1139 EKHRADLSRELEEISGRLEEAGGATAAQIE------MNKKREAEFQKM------------ 1180
Query: 4114 AGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELED 4284
RR EE+ Q LRKK+ L +Q++ + K+++ + K +++ E++D
Sbjct: 1181 ----RRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDD 1236
Query: 4285 SSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNE 4464
+ +E+V + + EK + E Q++E + +D +Q + +++
Sbjct: 1237 LASNMESVSKAKANLEKMCRTLEDQLSEFKT--------KDEQNQRM----------ISD 1278
Query: 4465 VDIMKEHLE-ESDRVRRSLQQELQDSISNKDDFGKNV--HELEKAKRSLEAELNDMRVQM 4635
+ + L+ ES R Q + +D + ++ GK ++E+ KR LE E+
Sbjct: 1279 LSAQRARLQTESGEYAR--QADEKDGLISQLSRGKQAFTQQIEELKRQLEEEIKAKNALA 1336
Query: 4636 EELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRR----GLLKQIRDLENE 4803
L+ + R + E +A K E RA+S + E + R +++ +LE
Sbjct: 1337 HSLQSARHDCDLLREQYEEELEA-KGELQRALSKANSEVAQWRTKYETDAIQRTEELEEA 1395
Query: 4804 LENEKRGKSG------------AVSHRKKIE----NQIGELEQQLEVANRLKEEYXXXXX 4935
K GK+G +VS+ +I +L +Q+ + E
Sbjct: 1396 KYVGKVGKAGRKLLSPGPFPLYSVSYPCDFSLFPAEEISDLTEQIAEGGKAIHELEKVKK 1455
Query: 4936 XXXXXXXEYQIECEEARQAKE-----------DIAALLREADRKFRAVEAEREQLREAN- 5079
E Q EEA + E ++ + E DRK + E +QL+ +
Sbjct: 1456 QIEQEKSEIQAALEEAEASLEHEEGKILRLQLELNQVKSEIDRKIAEKDEEIDQLKRNHL 1515
Query: 5080 ---EGLMQARKQXXXXXXXXXXXRAKGGG------ISSEEKRRLEAKIAQXXXXXXXXQS 5232
E L + + K G I R+ A+ +
Sbjct: 1516 RIVESLQSSLDAEIRSRNEALRLKKKMEGDLNEMEIQLSHANRVAAEAQKNLRNTQAVLK 1575
Query: 5233 NCELAIDKQRKAQVQL-EQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQ 5409
+ ++ +D + Q L EQ+ L + E + LE++N K EL
Sbjct: 1576 DTQIHLDDALRTQEDLKEQVAMVERKTNLLQAEIEDLRAPLEQTNPSKKVAEQELMDAVN 1635
Query: 5410 SRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAK 5589
++ L +V+ LE +++ E + A + R+ E+R+ + T Q E++++ + +
Sbjct: 1636 -----RVHLLHTQVRELEGEVDAEQKRSAEAVKGVRKYERRVKELTYQSEEDRKNILRLQ 1690
Query: 5590 ELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+L++K +K ++ +RQ +EAE+ + +K R +Q E ++
Sbjct: 1691 DLVDKLQMKVKSYKRQSEEAEELSNVNLSKFRKIQHELEE 1730
Score = 95.9 bits (237), Expect = 1e-17
Identities = 152/745 (20%), Positives = 292/745 (38%), Gaps = 42/745 (5%)
Frame = +1
Query: 2560 RAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQ 2739
R + +L+ + ++ +E+D ++ ++KL + E + IQ +++ E +L LQ
Sbjct: 1059 RKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQLLGMQLQKKIKELQ 1118
Query: 2740 TRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKT 2919
R +ELE + +R S R ++E + +
Sbjct: 1119 ARIEELEEEIE--AERTSRAKAEKHRADLSR--ELEEISGRLEEAGGATAAQIEMNKKRE 1174
Query: 2920 NVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV-KAKGRLE 3096
Q +A G + +D+ +R K + K K L+
Sbjct: 1175 AEFQKMRRDLEEATLQHEATAAALRKKHADSTAELG---EQIDNLQRVKQKLEKEKSELK 1231
Query: 3097 NQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQ 3276
++ +L ++ + K+ LE+ R L +L + K + + +L+ Q + E
Sbjct: 1232 MEIDDLASNMESVSKAKANLEKMCRTLEDQLSEFKTKDEQNQRMISDLSAQRARLQTESG 1291
Query: 3277 HQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKG 3456
+ DE+ ++ + + + I+EL+ +E E A+N + + + ++
Sbjct: 1292 EYARQADEKDGLISQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHSLQSARHDCDLLRE 1351
Query: 3457 DVLDKVDEATMLQDLMSRKDEEVNA--TKRAIEQIQHTME-------GKIEEQKAKF--- 3600
++++ LQ +S+ + EV TK + IQ T E GK+ + K
Sbjct: 1352 QYEEELEAKGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKYVGKVGKAGRKLLSP 1411
Query: 3601 ------------------SRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALL 3726
+ ++ +L +QI + K +LEK + Q +QE++++ + AL
Sbjct: 1412 GPFPLYSVSYPCDFSLFPAEEISDLTEQIAEGGKAIHELEKVKKQIEQEKSEI--QAALE 1469
Query: 3727 QASRADIDKKRKIHEAHL------MEIQANLAESDEHKRTLIDQLERSRDELDHLNRVRE 3888
+A + ++ KI L EI +AE DE IDQL+R+ HL V
Sbjct: 1470 EAEASLEHEEGKILRLQLELNQVKSEIDRKIAEKDEE----IDQLKRN-----HLRIVES 1520
Query: 3889 EEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEG 4068
+ A ++ R +L AN A E +KN L + + +
Sbjct: 1521 LQSSLDAEIRSRNEALRLKKKMEGDLNEMEIQLSHANRVAA---EAQKN-LRNTQAVLKD 1576
Query: 4069 LRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERIL 4248
+ HL+ +A R E+ Q RK NL LQ ++E+ E+
Sbjct: 1577 TQIHLD-----------DALRTQEDLKEQVAMVERKTNL-----LQAEIEDLRAPLEQTN 1620
Query: 4249 QSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELR 4428
SKK +QEL D+ + + R+ E + + AE V+K ++ +
Sbjct: 1621 PSKKVAEQELMDAVNRVHLLHTQVRELEGEVDAEQKRSAEAVKGVRKYERRVKELTYQSE 1680
Query: 4429 DRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKD--DFGKNVHELEKAKRS- 4599
+ +L L + VD ++ ++ R Q E + +SN + F K HELE+A+
Sbjct: 1681 EDRKNILRLQDLVDKLQMKVKSYKR-----QSEEAEELSNVNLSKFRKIQHELEEAEERA 1735
Query: 4600 --LEAELNDMRVQMEELEDNLQIAE 4668
E+++N +R + E ++ E
Sbjct: 1736 DIAESQVNKLRAKSREFHRRIEEEE 1760
Score = 95.5 bits (236), Expect = 1e-17
Identities = 134/727 (18%), Positives = 297/727 (40%), Gaps = 16/727 (2%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A ++ E+ +++ + + +R +LE++ + QE+ D+ ++ + AD ++
Sbjct: 852 EKEMANMKQEFEKTKEELAKSEAKRKELEEKMVKLVQEKNDLQLQVQAEADALADAEERC 911
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E+ + +E L + + DE L + ++ E A ++
Sbjct: 912 DQLIKTKIQLEAKVKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ K A N+ + L +E AL +E +K +
Sbjct: 972 KE---------------------KHATENKVKNLTEEMAAL----DETIVKLTKEKKALQ 1006
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
A Q + + E+ VN L + + K + V+ L+ LE+ + + + ++K+K++ +L
Sbjct: 1007 EAHQQTLDDLQAEEDKVNT-LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDL 1065
Query: 4279 E---DSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL 4449
+ DS M+LEN + D + ++K FE + ++ ++ L + + +++++ + R+
Sbjct: 1066 KLAHDSIMDLENDK-QQLDEKLKKKDFEISQIQSKIEDEQLLGMQ--LQKKIKELQARIE 1122
Query: 4450 SLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRV 4629
L E++ + ++++ R L +EL++ ++ G + + EAE MR
Sbjct: 1123 ELEEEIEAERTSRAKAEKHRADLSRELEEISGRLEEAGGATAAQIEMNKKREAEFQKMRR 1182
Query: 4630 QMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELE 4809
+EE + A + + A E + + E+++ L +I DL + +E
Sbjct: 1183 DLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNME 1242
Query: 4810 NEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQ 4989
+ + K+ + +E+Q+ E + + E R+ + EY ARQ
Sbjct: 1243 SVSKAKANLEKMCRTLEDQLSEFKTKDEQNQRMISDLSAQRARLQTESGEY------ARQ 1296
Query: 4990 AKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSE 5169
A E L+ + R +A + E+L
Sbjct: 1297 ADEK-DGLISQLSRGKQAFTQQIEEL---------------------------------- 1321
Query: 5170 EKRRLEAKIAQXXXXXXXXQS---NCELA---IDKQRKAQVQLEQITTDLSMERTLNQKT 5331
KR+LE +I QS +C+L +++ +A+ +L++ + + E +T
Sbjct: 1322 -KRQLEEEIKAKNALAHSLQSARHDCDLLREQYEEELEAKGELQRALSKANSE-VAQWRT 1379
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRA 5511
+ E +++R+ +AK A + + V Y D +E
Sbjct: 1380 KYETDAIQRTEELEEAKYVGKVGKAGRKLLSPGPFPLYSVSYPCDFSLFPAEE------- 1432
Query: 5512 ARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNV 5691
++D T+Q + +A + +++ ++ + ++ L+EAE + E K +
Sbjct: 1433 -------ISDLTEQIAEGGKAIHELEKVKKQIEQEKSEIQAALEEAEASLEHEEGKILRL 1485
Query: 5692 QREADDL 5712
Q E + +
Sbjct: 1486 QLELNQV 1492
Score = 70.9 bits (172), Expect = 4e-10
Identities = 104/504 (20%), Positives = 195/504 (38%), Gaps = 11/504 (2%)
Frame = +1
Query: 4264 IQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQK---ALLDRDAMSQELRDR 4434
++QE E + EL A ++ E++ K + + ++ VQ AL D + +L
Sbjct: 858 MKQEFEKTKEELAKSEAKRKELEEKMVKLVQEKNDLQLQVQAEADALADAEERCDQLIKT 917
Query: 4435 ETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAEL 4614
+ ++ + + EV E EE + + +++L+D S + K++ +LE +E E
Sbjct: 918 KIQLEAKVKEVTERAEDEEEINAELTAKKRKLEDECS---ELKKDIDDLELTLAKVEKEK 974
Query: 4615 NDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLL------ 4776
+ +++ L + + ++ ++L +AL+ + + D++AEE + L
Sbjct: 975 HATENKVKNLTEEMAALDETIVKLTKEKKALQEAHQQTLD--DLQAEEDKVNTLTKAKTK 1032
Query: 4777 --KQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXX 4950
+Q+ DLE LE EK+ R +E +LE L++A+ +
Sbjct: 1033 LEQQVDDLEGSLEQEKK-------LRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDEK 1085
Query: 4951 XXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXX 5130
+ E + + ED L + +K + ++A E+L E E
Sbjct: 1086 LKKKDFEISQIQSKIEDEQLLGMQLQKKIKELQARIEELEEEIEA--------------E 1131
Query: 5131 XXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSME 5310
RAK ++ R LE + +LE+ + +
Sbjct: 1132 RTSRAKAEKHRADLSRELE-------------------------EISGRLEEAGGATAAQ 1166
Query: 5311 RTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQE 5490
+N+K EAE Q + R +LE A + A AAL K D G++
Sbjct: 1167 IEMNKKREAEFQKMRR----------DLEE-ATLQHEATAAALRKK---HADSTAELGEQ 1212
Query: 5491 KTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRE 5670
R ++LEK ++ + +D +E + NL + ED++S
Sbjct: 1213 IDNLQRVKQKLEKEKSELKMEIDD-------LASNMESVSKAKANLEKMCRTLEDQLSEF 1265
Query: 5671 RTKHRNVQREADDLLDANEQLTRE 5742
+TK QR DL +L E
Sbjct: 1266 KTKDEQNQRMISDLSAQRARLQTE 1289
Score = 49.7 bits (117), Expect = 9e-04
Identities = 65/365 (17%), Positives = 138/365 (37%), Gaps = 1/365 (0%)
Frame = +1
Query: 4654 LQIAEDARLRLEVTNQALKSESDRAISN-KDVEAEEKRRGLLKQIRDLENELENEKRGKS 4830
L+ AE + + + K++ + A S K E EEK L+++ DL+ +++ E +
Sbjct: 846 LKSAESEKEMANMKQEFEKTKEELAKSEAKRKELEEKMVKLVQEKNDLQLQVQAEADALA 905
Query: 4831 GAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAA 5010
A ++ +LE +++ E+ + + EC E ++ +D+
Sbjct: 906 DAEERCDQLIKTKIQLEAKVKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLEL 965
Query: 5011 LLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEA 5190
L + +++ A E + + L E L + + ++EK+ L+
Sbjct: 966 TLAKVEKEKHATENKVKNLTEEMAALDETIVKL------------------TKEKKALQE 1007
Query: 5191 KIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRD 5370
Q + + K + Q++ + L E+ L E K+ LE
Sbjct: 1008 AHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLE----- 1062
Query: 5371 YKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQ 5550
G A + LE Q L+++L ++ + ++
Sbjct: 1063 ----------GDLKLAHDSIMDLENDKQQLDEKL--------------KKKDFEISQIQS 1098
Query: 5551 QFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQ 5730
+ EDE+ Q ++ K + L+ +++E E+E+ ERT ++ DL E+
Sbjct: 1099 KIEDEQLLGMQLQK-------KIKELQARIEELEEEIEAERTSRAKAEKHRADLSRELEE 1151
Query: 5731 LTREL 5745
++ L
Sbjct: 1152 ISGRL 1156
>gi|47847498|dbj|BAD21421.1| mFLJ00279 protein [Mus musculus]
Length = 1335
Score = 961 bits (2484), Expect = 0.0
Identities = 513/1288 (39%), Positives = 794/1288 (60%), Gaps = 7/1288 (0%)
Frame = +1
Query: 1903 MNETAF--GMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSN 2076
M+ETA ++RKGMFRTV QL+KEQL KLM TLRNT+P+FVRCIIPNHEKK+GK++ +
Sbjct: 2 MSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPH 61
Query: 2077 LVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITA 2256
LVL+QLRCNGVLEGIRICRQGFPNRV FQEFR RYEILTP+ IPK F+DGK++ MI A
Sbjct: 62 LVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKGFMDGKQACVLMIKA 121
Query: 2257 LDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXX 2436
L++D+NLYRIGQSKVFFR GVLAHLEEERDLK+T +I+ FQA CRG+L+R+ +
Sbjct: 122 LELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQL 181
Query: 2437 XXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEH 2616
N AYL+LRNWQWWRLFTKVKPLL R +DE+ AK+ EL +E+ L E+
Sbjct: 182 TAMKVLQRNCAAYLRLRNWQWWRLFTKVKPLLNSIRHEDELLAKEAELTKVREKHLAAEN 241
Query: 2617 DFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSX 2796
E E Q++ E+ +QEQLQ E+E AE +++R RL + QELE I +D+ R+
Sbjct: 242 RLTEMETMQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEE 301
Query: 2797 XXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDA 2976
++K + +++ +K + +D
Sbjct: 302 EEERCQYLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEDQIIMEDQ 361
Query: 2977 YDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSEL 3156
TT L++ EE++K K K + E + +LE+ L RE + + EL
Sbjct: 362 NCKLAKEKKLLEDRVAEFTTNLMEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQEL 421
Query: 3157 EQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQM 3336
E+ +RKL + D D +AE ++ EL QL K++EELQ L R +EE+A + K++
Sbjct: 422 EKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKI 481
Query: 3337 RDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKD 3516
R+++T I EL+ED+E+ER +RNKAE +R++ +LE +K ++ D +D Q+L S+++
Sbjct: 482 RELETQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKRE 541
Query: 3517 EEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQER 3696
+EV+ K+ +E T E +I+E + K S+ VEEL DQ+EQ K+ ++ LEK + + ER
Sbjct: 542 QEVSILKKTLEDEAKTHEAQIQEMRQKHSQAVEELADQLEQTKRVKATLEKAKQTLENER 601
Query: 3697 ADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLN 3876
++A E+ L + D + KRK EA L E+Q +E + + L D++ + + ELD +
Sbjct: 602 GELANEVKALLQGKGDSEHKRKKVEAQLQELQVKFSEGERVRTELADKVTKLQVELDSVT 661
Query: 3877 RVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKE 4056
+ + + + + + + R K++ + +Q+EDEKN+ ++ E
Sbjct: 662 GLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQMEDEKNSFREQLE 721
Query: 4057 EAEGLRAHLEKEIHAARQGAGEARRKAEESVN--QQLEELRKKNLRDVEHLQKQLEESEV 4230
E E + +LEK+I + ++K E+ V + EE +++ +D+E L ++LEE
Sbjct: 722 EEEEAKRNLEKQIATLHAQVTDMKKKMEDGVGCLETAEEAKRRLQKDLEGLSQRLEEKVA 781
Query: 4231 AKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDA 4410
A +++ ++K ++QQEL+D ++L++ R S + EK+QKKF+ +AEE+ K +RD
Sbjct: 782 AYDKLEKTKTRLQQELDDLLVDLDHQRQSVSNLEKKQKKFDQLLAEEKTISAKYAEERDR 841
Query: 4411 MSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKA 4590
E R++ET+ LSL ++ E E +R+ + + E++D +S+KDD GK+VHELEK+
Sbjct: 842 AEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKS 901
Query: 4591 KRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRG 4770
KR+LE ++ +M+ Q+EELED LQ EDA+LRLEV QA+K++ +R + +D ++EEK++
Sbjct: 902 KRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQ 961
Query: 4771 LLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXX 4950
L++Q+R++E ELE+E++ +S A++ RKK+E + +LE ++ AN+ +EE
Sbjct: 962 LVRQVREMEAELEDERKQRSMAMAARKKLEMDLKDLEAHIDTANKNREEAIKQLRKLQAQ 1021
Query: 4951 XXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXX 5130
+ E ++ R ++E+I A +E ++K +++EAE QL+E +A++Q
Sbjct: 1022 MKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDEL 1081
Query: 5131 XXXRAKG---GGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDL 5301
A G ++ EEKRRLEA+IAQ Q N EL D+ +KA +Q++QI TDL
Sbjct: 1082 ADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDL 1141
Query: 5302 SMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVE 5481
++ER+ QK E +Q LER N++ KAK+ E+ES +S+ +A +AALEAK+ LE+QL+ E
Sbjct: 1142 NLERSHAQKNENARQQLERQNKELKAKLQEMESAVKSKYKASIAALEAKIAQLEEQLDNE 1201
Query: 5482 GQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEM 5661
+E+ AA++ RR EK+L D Q EDE+R EQ K+ +K++ + + L+RQL+EAE+E
Sbjct: 1202 TKERQAASKQVRRTEKKLKDVLLQVEDERRNAEQFKDQADKASTRLKQLKRQLEEAEEEA 1261
Query: 5662 SRERTKHRNVQREADDLLDANEQLTREL 5745
R R +QRE +D + + + RE+
Sbjct: 1262 QRANASRRKLQRELEDATETADAMNREV 1289
>gi|47206494|emb|CAF92339.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 1477
Score = 949 bits (2452), Expect = 0.0
Identities = 537/1434 (37%), Positives = 830/1434 (57%), Gaps = 105/1434 (7%)
Frame = +1
Query: 1759 VDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GM 1926
VDY+A WL KNMDPLN+NV L+ NS+ FV +WKD + G+ A+M++T+
Sbjct: 1 VDYNATAWLTKNMDPLNDNVTTLLSNSSSQFVQDLWKDTDRVVGLDTLAKMSDTSMPSAS 60
Query: 1927 RSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNG 2106
+++KGMFRTV QL+KE L KLMTTL NT P+FVRCIIPNHEK++GK++++LVLEQLRCNG
Sbjct: 61 KTKKGMFRTVGQLYKESLAKLMTTLHNTQPNFVRCIIPNHEKRAGKLDAHLVLEQLRCNG 120
Query: 2107 VLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITA---------- 2256
VLEGIRICRQGFPNR+ FQEFR RYEILTP IPK F+DGK++ M+
Sbjct: 121 VLEGIRICRQGFPNRIVFQEFRQRYEILTPSAIPKGFMDGKQACCLMVNTHSRKIPRLII 180
Query: 2257 -------------------------LDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTA 2361
LD+D NL+RIGQSK+FFRTGVLA LEEERDLK+T
Sbjct: 181 QHICTVKTHLLLCLMLSFPVLQIKHLDLDPNLFRIGQSKIFFRTGVLAQLEEERDLKITV 240
Query: 2362 LIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVT 2541
+I+ FQAQ RGFL+R+ + N AYLKLRNWQWWRLFTKVKPLLQVT
Sbjct: 241 IIIAFQAQARGFLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVT 300
Query: 2542 RTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDD 2721
R ++E+ KD+EL+ KE LK E + +E K V+ ER +QEQLQ E+E AE ++
Sbjct: 301 RQEEEMSLKDEELKRAKEVSLKFESELKEIALKHTSVVEERNALQEQLQAETELFAEAEE 360
Query: 2722 IRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXX 2901
+R RL + QELE I+++M RL ++K + +++
Sbjct: 361 MRVRLAAKKQELEEILHEMEARLDDEEERAQALLLDKKKMQQQMQELEEHLEEEEDARQK 420
Query: 2902 XXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKA 3081
+K + +D + ++T L + EE++K+ K
Sbjct: 421 LQLEKVTCEGKIKKLEDEILVMEDHNNKLLKERKLMEDRIADISTNLAEEEEKSKNLTKL 480
Query: 3082 KGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKR 3261
K + E+ + ELE L +E + + EL++ KRKL AE D ++ +A+ ++ EL QL K+
Sbjct: 481 KNKHESMISELEVRLKKEEKCRQELDKAKRKLEAESNDLQEQIADLQAQIAELKAQLAKK 540
Query: 3262 DEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQL 3441
+EELQ+ L R ++E A K++R+++ I +L+ED+++ER ARNKAE +R++ +L
Sbjct: 541 EEELQNALARLEDEMAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKIKRDLGEEL 600
Query: 3442 EKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEEL 3621
E +K ++ D +D Q+L +++++EV KRAIE+ T E ++ E + K ++ VEEL
Sbjct: 601 EALKSELEDTLDTTATQQELRAKREQEVTVLKRAIEEENRTHEAQVHEMRQKHTQAVEEL 660
Query: 3622 HDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL 3801
+Q+EQ K+ +S LEK + ++E +++ E+ L ++ D + KRK E + ++Q+
Sbjct: 661 TEQLEQSKRVKSNLEKAKQALEKETSELTMEVRSLVQAKQDGEHKRKKLEGQVADLQSRF 720
Query: 3802 AESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXX------XXXXXXX 3963
A+S++ K L ++ + EL+ + + E E + + +++
Sbjct: 721 ADSEKQKADLGERCSKITIELEGVTNLLNEAESKNIKLSKDVSSITSQLQDTQIHLSQQE 780
Query: 3964 XXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEE 4143
TR K+ + RQ ED+KN+L ++ EE + ++E+ + ++++K EE
Sbjct: 781 LLAEETRQKLQLSTKLRQAEDDKNSLQEQLEEEMEAKRNVERHVSTLNLQLSDSKKKLEE 840
Query: 4144 SV--NQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRAS 4317
+ LEE +K+ RD+E Q EE A +++ ++K ++QQELED+ M+L+N R
Sbjct: 841 MTANAEMLEESKKRLQRDLEAANTQYEEKASAYDKLEKTKNRLQQELEDTLMDLDNQRQI 900
Query: 4318 HRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEES 4497
+ EK+QKKF+ +AEE+ K +RD E R++ET+ LSL ++ ++ EE
Sbjct: 901 VSNLEKKQKKFDQMLAEEKSISCKYAEERDRAEAEAREKETKALSLARALEEAQDSREEL 960
Query: 4498 DRVRRSLQQELQDSISNKDDFGKN----------------------------VHELEKAK 4593
+R ++L+ E++D IS+KDD GKN VHELEK+K
Sbjct: 961 ERANKALRIEMEDLISSKDDVGKNVGGNIQDCFLKGVFHIYMMVNSYVYFRQVHELEKSK 1020
Query: 4594 RSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGL 4773
R LEA++ +M+ Q+EELED LQ AEDA+LRLEV QALK++ +R + +D EEK+R L
Sbjct: 1021 RGLEAQVEEMKTQLEELEDELQAAEDAKLRLEVNMQALKAQFERDLQGRDEMGEEKKRQL 1080
Query: 4774 LKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXX 4953
+KQ+R+LE ELE+E++ ++ A + +KK+E I +LE Q+E A++ ++E
Sbjct: 1081 IKQVRELETELEDERKQRAQATAAKKKLETDIKDLEGQIETASKGRDEAIKQLRKLQAQM 1140
Query: 4954 XEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREA-----------------NE 5082
++Q E ++A A+E++ + +E+++K +++EAE QL+E
Sbjct: 1141 KDFQRELDDAHAAREEVLSAAKESEKKAKSLEAELMQLQEVTWLIPNTASAGGTRQTLRS 1200
Query: 5083 GLM----------QARKQXXX---XXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXX 5223
GL +ARKQ A G ++EKRRLEA+IAQ
Sbjct: 1201 GLFFFLQDLAAAERARKQAEAERDELADELASNASGKSALADEKRRLEARIAQLEEELEE 1260
Query: 5224 XQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESG 5403
Q N EL D+ RK+ Q++Q+ +L ER+ +QK E+ +Q LER N++ KAK+ E+E+
Sbjct: 1261 EQGNMELLNDRLRKSSQQVDQLNNELQTERSTSQKNESARQQLERQNKELKAKLQEMENQ 1320
Query: 5404 AQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQ 5583
+S+ ++ ++ALEAKV LE+QL E +EK A+ ++ R+ +K++ D Q EDE++ EQ
Sbjct: 1321 VKSKFKSSISALEAKVAQLEEQLEQENREKQASAKSLRQKDKKMKDLIIQVEDERKQAEQ 1380
Query: 5584 AKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
K+ EKS + + L+RQL+E+E+E R R +QRE D+ + + L RE+
Sbjct: 1381 YKDQAEKSTARVKQLKRQLEESEEESQRATAARRKLQRELDEATETADALGREV 1434
Score = 50.4 bits (119), Expect = 5e-04
Identities = 37/203 (18%), Positives = 91/203 (44%), Gaps = 11/203 (5%)
Frame = +1
Query: 3055 ERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKM-GKV 3231
+R + + +L N+L + + +LE+ ++L A+L++ ++ + K +
Sbjct: 1270 DRLRKSSQQVDQLNNELQTERSTSQKNESARQQLERQNKELKAKLQEMENQVKSKFKSSI 1329
Query: 3232 EELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
L ++ + +E+L+ + + ++ K+M+D+ +++ R+ E ++ K+
Sbjct: 1330 SALEAKVAQLEEQLEQENREKQASAKSLRQKDKKMKDLIIQVEDERKQAEQYKDQAEKST 1389
Query: 3412 MTRREVVAQLEK----------VKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQH 3561
+++ QLE+ + + ++DEAT D + R EVN+ K + +
Sbjct: 1390 ARVKQLKRQLEESEEESQRATAARRKLQRELDEATETADALGR---EVNSLKSKLRRGNE 1446
Query: 3562 TMEGKIEEQKAKFSRQVEELHDQ 3630
G + R VE++ D+
Sbjct: 1447 PSFGSTPRRMGGGRRVVEDMSDE 1469
>gi|31235868|ref|XP_319313.1| ENSANGP00000023782 [Anopheles gambiae]
gi|30174788|gb|EAA43614.1| ENSANGP00000023782 [Anopheles gambiae str.
PEST]
Length = 1739
Score = 948 bits (2451), Expect = 0.0
Identities = 582/1721 (33%), Positives = 949/1721 (54%), Gaps = 29/1721 (1%)
Frame = +1
Query: 655 GELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRV 834
G LE Q++Q NP+LEAFGN+KTV+NDNSSRFGKFIRI+F SG ++GA+IE YLLEK+RV
Sbjct: 10 GSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFTGSGKLAGADIETYLLEKARV 69
Query: 835 LRQAQDERSFHIFYQILRGCSAKEKSE--YLLEGVDNYRFLVNRGITLPNVDDVQEFHST 1008
+ Q ERS+HIFYQI+ G S K E +L + +Y + IT+PNVDD +E T
Sbjct: 70 ISQQTLERSYHIFYQIMSG-SVKGLKEMCFLSNDIYDYNSVSQGKITIPNVDDGEECLLT 128
Query: 1009 INSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPV 1188
+ ++GF +E +I R+ SAV+ +G ++F Q+ + +QA +V LLG+
Sbjct: 129 DEAFNVLGFTQEEKDNIYRITSAVMHMGRMQFKQKGREEQAEADGTEDGDRVAKLLGVGT 188
Query: 1189 IELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHR 1368
+L K L+PRIKVG EFV K QN++Q +V A+ K ++RLFKWLV + N++LD T +
Sbjct: 189 DDLYKNLLKPRIKVGNEFVTKGQNKDQVTNSVGALCKGIFDRLFKWLVKKCNETLD-TKQ 247
Query: 1369 QGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFI 1548
+ A FIG+LDIAGFEIFD N FEQ+CIN+TNEKLQQ FN+ MF+LEQEEY++EGI W FI
Sbjct: 248 KRAQFIGVLDIAGFEIFDFNGFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGINWAFI 307
Query: 1549 DFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPKFIVPDMRS- 1722
DFG+DL ++LIEKPMG+L++L+EE +FPKA D++F EKL H K F+ P
Sbjct: 308 DFGMDLLACVELIEKPMGILSILEEESMFPKATDQTFAEKLMTNHLGKSAPFMKPRPPKP 367
Query: 1723 ---KSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWKD--AEFAG 1887
HFA+ HYAG V Y+ WL KN DPLN+ VV + ++ + I+ D + A
Sbjct: 368 GIPAGHFAIGHYAGVVSYNITGWLEKNKDPLNDTVVDQFKKGSNALMVEIFADHPGQSAD 427
Query: 1888 ICAAEMNETAFGMRSRKGM-FRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGK 2064
AA+ G R +KG F TVS +KEQL LMTTL++T PHFVRCIIPN K +G
Sbjct: 428 PAAAK------GGRGKKGAGFATVSSSYKEQLNNLMTTLKSTQPHFVRCIIPNEMKTAGV 481
Query: 2065 INSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRK 2244
++++LV+ QL CNGVLEGIRICR+GFPNR+ + +F+ RY IL P + +GK++ K
Sbjct: 482 VDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKLRYLILAPAAMQAE-TEGKKAAEK 540
Query: 2245 MITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXX 2424
A+ +D + YRIG +KVFFR GVL +EE RD +L+ ++ QA CRG+LSR+ +
Sbjct: 541 CFEAIGLDPDSYRIGHTKVFFRAGVLGQMEEFRDERLSKIMSWMQAWCRGYLSRKEFKKM 600
Query: 2425 XXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLL 2604
N YLKLR W WW+L+ KVKPLL V+R +D+I +++ +E
Sbjct: 601 QEQRVSLEIVQRNLRKYLKLRTWAWWKLWQKVKPLLNVSRVEDQIAKLEEKATKAQEAYE 660
Query: 2605 KMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRD 2784
K E +E E +++ E+ + + L E E + +L + +LE + D ++
Sbjct: 661 KEEKLRKELEALNSKLLAEKTALLDSLSGEKGALQEYQEKAAKLTAQKNDLENQLRDTQE 720
Query: 2785 RLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXX 2964
RL+ ++K + + DK + D
Sbjct: 721 RLAQEEDARNQLFQTKKKLEQEIGSQKKDAEDLELQIQKIEQDKASKDHQIRNLNDEIAH 780
Query: 2965 XQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQY 3144
+ + +L E++ H K K +LE L ELE L RE++
Sbjct: 781 QDELINKLNKEKKMQGEVNQKTAEELQAAEDKVNHLNKVKAKLEQTLDELEDSLEREKKL 840
Query: 3145 KSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLM 3324
+ ++E+ KRK+ +L+ +++ +A+ +EL ++++D+E+ + ++E + V +
Sbjct: 841 RGDVEKAKRKVEGDLKLTQEAVADLERNKKELEQTVLRKDKEISALSAKLEDEQSLVGKL 900
Query: 3325 QKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ-DL 3501
QKQ++++Q I+EL E++E ER AR KAE R ++ +LE++ G+ L++ AT Q +L
Sbjct: 901 QKQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEEL-GERLEEAGGATSAQIEL 959
Query: 3502 MSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQ 3681
+++ E+ +R +E+ EG + + K + V E+ +Q++Q K +++ EK++ Q
Sbjct: 960 NKKREAELAKLRRDLEEANIQHEGTLANLRKKHNDAVAEMAEQVDQLNKLKTKAEKERTQ 1019
Query: 3682 ADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDE 3861
E D L +A +K K + L E+Q+ L DE RTL D + S+ +
Sbjct: 1020 YFAELNDARIGCDQLSNEKAAQEKIAKQLQHTLNEVQSKL---DETNRTLND-FDASKKK 1075
Query: 3862 L----DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDE 4029
L L R E+ E + + + + R + + + R LE +
Sbjct: 1076 LSIENSDLLRQLEDAESQVSQLSKIKISLTQQLEDTKRLADEEARERATLLGKFRNLEHD 1135
Query: 4030 KNALLDE-KEEAEGLRAHLEKEIHAARQGAGEARRKAEE---SVNQQLEELRKK---NLR 4188
+ L ++ +EEAEG + +++++ A A R K E + ++LEE ++K L
Sbjct: 1136 LDNLREQVEEEAEG-KGDIQRQLSKANAEAQLWRSKYESEGVARAEELEEAKRKLQARLA 1194
Query: 4189 DVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAE 4368
+ E + L + +A E+ +K+++ E+ED +E++ + +EK+QK F+ + E
Sbjct: 1195 EAEETIESLNQKCIALEK---TKQRLATEVEDLQLEVDRASSIANAAEKKQKAFDKIIGE 1251
Query: 4369 ERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISN 4548
++ V + DA +E R+ T + L + +E LE R ++L E++D +
Sbjct: 1252 WKLKVDDLAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQ 1311
Query: 4549 KDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRA 4728
+ G+N+HE+EK+++ LEAE ++++ +EE E L+ E+ LR ++ ++ E DR
Sbjct: 1312 IGEGGRNIHEIEKSRKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEIDRR 1371
Query: 4729 ISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRL 4908
I K+ E E R+ + + ++ LE E +GK+ A+ +KK+E I ELE L+ AN+
Sbjct: 1372 IQEKEEEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKA 1431
Query: 4909 KEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQ----LREA 5076
E + Q EE ++A++D L ++R+ A++ E E+ L +A
Sbjct: 1432 NAEAQKNIKRYQQQLKDVQSALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQA 1491
Query: 5077 NEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDK 5256
+ G QA ++ A+ I++ KR+LE+++ + + + +K
Sbjct: 1492 DRGRRQAEQELSDAHEQLNEVSAQNASIAA-AKRKLESELQTLHSDLDELLNEAKNSEEK 1550
Query: 5257 QRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAA 5436
+KA V ++ +L E+ Q E +++LE+ ++ + ++ E ES A + +
Sbjct: 1551 AKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAESNALKGGKKAIQK 1610
Query: 5437 LEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLK 5616
LE +V+ LE +L+ E + A + R+ E+R+ + T Q E++++ +E+ ++L++K K
Sbjct: 1611 LEQRVRELESELDSEQRRHADAQKNLRKSERRIKELTFQSEEDRKNHERMQDLVDKLQQK 1670
Query: 5617 NRNLRRQLDEAEDEMSRERTKHRNVQR---EADDLLDANEQ 5730
+ +RQ++EAE+ + K R Q+ EA++ D EQ
Sbjct: 1671 IKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADIAEQ 1711
Score = 155 bits (391), Expect = 1e-35
Identities = 186/948 (19%), Positives = 398/948 (41%), Gaps = 60/948 (6%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMK--- 3258
+LE + + ++ +E + + ELE KLLAE D L+ + G ++E + K
Sbjct: 647 KLEEKATKAQEAYEKEEKLRKELEALNSKLLAEKTALLDSLSGEKGALQEYQEKAAKLTA 706
Query: 3259 RDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQ 3438
+ +L++QL E A Q D + + + ++ +E E ++ K ++ Q
Sbjct: 707 QKNDLENQLRDTQERLA-------QEEDARNQLFQTKKKLEQEIGSQKK---DAEDLELQ 756
Query: 3439 LEKVKGDVLDKVDEATMLQDLMSRKDEEVN-----------ATKRAIEQIQHTME--GKI 3579
++K++ D K + L D ++ +DE +N ++ E++Q + +
Sbjct: 757 IQKIEQDKASKDHQIRNLNDEIAHQDELINKLNKEKKMQGEVNQKTAEELQAAEDKVNHL 816
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKR 3759
+ KAK + ++EL D +E+ KK R +EK + + + + + L Q + AD+++ +
Sbjct: 817 NKVKAKLEQTLDELEDSLEREKKLRGDVEKAKRKVEGD-------LKLTQEAVADLERNK 869
Query: 3760 KIHEAHLM----EIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRL 3927
K E ++ EI A L+ E +++L+ +L++ EL R+ E EE A Q R
Sbjct: 870 KELEQTVLRKDKEISA-LSAKLEDEQSLVGKLQKQIKELQA--RIEELEEEVEAERQAR- 925
Query: 3928 ATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAAR 4107
+ + + AR+LE+ L E+ E G + E++ R
Sbjct: 926 -----------------AKAEKQRADLARELEE-----LGERLEEAGGATSAQIELNKKR 963
Query: 4108 QGAGEARRKAEESVNQQ----LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQE 4275
+ R+ E N Q L LRKK+ V + +Q+++ K + + + + E
Sbjct: 964 EAELAKLRRDLEEANIQHEGTLANLRKKHNDAVAEMAEQVDQLNKLKTKAEKERTQYFAE 1023
Query: 4276 LEDSSM---ELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRV 4446
L D+ + +L N +A+ K+ + +++ + + L D DA ++L +
Sbjct: 1024 LNDARIGCDQLSNEKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSIENS-- 1081
Query: 4447 LSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMR 4626
LL +++ + + + +++ SL Q+L+D+ D+ + L R+LE +L+++R
Sbjct: 1082 -DLLRQLEDAESQVSQLSKIKISLTQQLEDTKRLADEEARERATLLGKFRNLEHDLDNLR 1140
Query: 4627 VQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENEL 4806
Q+EE + + + Q +S+ + + E EE +R L ++ + E +
Sbjct: 1141 EQVEEEAEGKGDIQRQLSKANAEAQLWRSKYESEGVARAEELEEAKRKLQARLAEAEETI 1200
Query: 4807 ENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEAR 4986
E+ + ++++ ++ +L+ +++ A+ + E++++ ++
Sbjct: 1201 ESLNQKCIALEKTKQRLATEVEDLQLEVDRASSIANAAEKKQKAFDKIIGEWKLKVDDLA 1260
Query: 4987 QAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISS 5166
+ R + ++ E+ +E E + + K +GG
Sbjct: 1261 AELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGRNIH 1320
Query: 5167 E---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEA 5337
E ++RLEA+ + ++ E +K +AQ++L Q+ ++ +R + +K E
Sbjct: 1321 EIEKSRKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEI--DRRIQEKEEE 1378
Query: 5338 EKQSLERSNRDYKAKITELESGAQSRARA--QMAALEAKVQYLEDQLNVEGQEKTAANRA 5511
+ + + R + LE+ A+ +A A LEA + LE L+ + A +
Sbjct: 1379 FENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQKN 1438
Query: 5512 ARRLEKRLNDTTQQFEDEKR----------------------------ANEQAKELLEKS 5607
+R +++L D E+E+R EQA ++
Sbjct: 1439 IKRYQQQLKDVQSALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRRQA 1498
Query: 5608 NLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
+ + QL+E + + R ++ E L ++L E N
Sbjct: 1499 EQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDELLNEAKN 1546
Score = 109 bits (272), Expect = 9e-22
Identities = 138/637 (21%), Positives = 266/637 (41%), Gaps = 88/637 (13%)
Frame = +1
Query: 3028 LTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDH 3207
L QL D E + K K L QL + ++ + E + ++ L R L +L++ ++
Sbjct: 1083 LLRQLEDAESQVSQLSKIKISLTQQLEDTKRLADEEARERATLLGKFRNLEHDLDNLREQ 1142
Query: 3208 LAEKMGKVEELNNQLMKRDEELQHQLTRYDEES-ANVTLMQKQMRDMQTTIDELREDMET 3384
+ E+ ++ QL K + E Q ++Y+ E A +++ R +Q + E E +E+
Sbjct: 1143 VEEEAEGKGDIQRQLSKANAEAQLWRSKYESEGVARAEELEEAKRKLQARLAEAEETIES 1202
Query: 3385 ERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRK----DEEVNATKRAIEQ 3552
E T++ + ++E D+ +VD A+ + + +K D+ + K ++
Sbjct: 1203 LNQKCIALEKTKQRLATEVE----DLQLEVDRASSIANAAEKKQKAFDKIIGEWKLKVDD 1258
Query: 3553 IQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQA 3732
+ ++ +E + +S ++ L E+ ++Q + ++ E D+ +I
Sbjct: 1259 LAAELDASQKECR-NYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGR 1317
Query: 3733 SRADIDKKRKIHEAHLMEIQANLAESD-----EHKRTLIDQLERS--RDELDHLNRVREE 3891
+ +I+K RK EA E+QA L E++ E + L QLE S R E+D + +EE
Sbjct: 1318 NIHEIEKSRKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEIDRRIQEKEE 1377
Query: 3892 E-EHAFANMQRRLATAXXXXXXXXXXXXXXTRLKI---ANINRARQLEDEKNALLDE--- 4050
E E+ N QR L + R+K A+IN D N E
Sbjct: 1378 EFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQK 1437
Query: 4051 -----KEEAEGLRAHLEKEIHA---ARQGAGEARRKAEESVNQ---------QLEELRKK 4179
+++ + +++ LE+E A AR+ G + R+A N+ Q + R++
Sbjct: 1438 NIKRYQQQLKDVQSALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRRQ 1497
Query: 4180 NLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKF--- 4350
+++ +QL E I +K+K++ EL+ +L+ + ++SE++ KK
Sbjct: 1498 AEQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDELLNEAKNSEEKAKKAMVD 1557
Query: 4351 ------ESQMAEERVAVQKALLDRDAMSQELRDR----------------------ETRV 4446
E + ++ Q+ L R A+ Q++++ E RV
Sbjct: 1558 AARLADELRAEQDHAQTQEKL--RKALEQQIKELQVRLDEAESNALKGGKKAIQKLEQRV 1615
Query: 4447 LSLLNEVDI-MKEHLE-------------------ESDRVRRSLQQELQDSISNK-DDFG 4563
L +E+D + H + E DR Q+L D + K +
Sbjct: 1616 RELESELDSEQRRHADAQKNLRKSERRIKELTFQSEEDRKNHERMQDLVDKLQQKIKTYK 1675
Query: 4564 KNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDA 4674
+ + E E+ A+ + ++EE E+ IAE A
Sbjct: 1676 RQIEEAEEIAALNLAKFRKAQQELEEAEERADIAEQA 1712
Score = 89.7 bits (221), Expect = 8e-16
Identities = 111/532 (20%), Positives = 233/532 (42%), Gaps = 11/532 (2%)
Frame = +1
Query: 4180 NLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQ 4359
N+ VE +LEE + + ++K+++ELE + +L + + DS +K
Sbjct: 637 NVSRVEDQIAKLEEKATKAQEAYEKEEKLRKELEALNSKLLAEKTALLDSLSGEK---GA 693
Query: 4360 MAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDS 4539
+ E + K ++ + +LRD + R L E D + + ++ L+QE+
Sbjct: 694 LQEYQEKAAKLTAQKNDLENQLRDTQER---LAQEEDARNQLFQ----TKKKLEQEIGSQ 746
Query: 4540 ISNKDDFGKNVHELEKAKRSLEAE---LNDMRVQMEELEDNLQIAEDARLRLEVTNQALK 4710
+ +D + ++E+ K S + + LND +EL + L ++ +++ EV +
Sbjct: 747 KKDAEDLELQIQKIEQDKASKDHQIRNLNDEIAHQDELINKLN--KEKKMQGEVNQKT-- 802
Query: 4711 SESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
+E +A +K + + L + + +LE+ LE EK+ + ++K+E + ++ +
Sbjct: 803 AEELQAAEDKVNHLNKVKAKLEQTLDELEDSLEREKKLRGDVEKAKRKVEGDLKLTQEAV 862
Query: 4891 EVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLR 5070
R K+E + +I A+ ED +L+ + ++ + ++A E+L
Sbjct: 863 ADLERNKKELEQTVLRK-----DKEISALSAKL--EDEQSLVGKLQKQIKELQARIEELE 915
Query: 5071 EANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAI 5250
E E QAR AK ++ R LE + + EL
Sbjct: 916 EEVEAERQAR--------------AKAEKQRADLARELEELGERLEEAGGATSAQIEL-- 959
Query: 5251 DKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITE-------LESGAQ 5409
+K + +L ++ DL ++ T A +L + + D A++ E L++ A+
Sbjct: 960 --NKKREAELAKLRRDLEEANIQHEGTLA---NLRKKHNDAVAEMAEQVDQLNKLKTKAE 1014
Query: 5410 SRARAQMAAL-EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQA 5586
A L +A++ DQL+ EK A + A++L+ LN+ + ++ R
Sbjct: 1015 KERTQYFAELNDARIGC--DQLS---NEKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDF 1069
Query: 5587 KELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
+K +++N +L RQL++AE ++S+ ++ ++ +D ++ RE
Sbjct: 1070 DASKKKLSIENSDLLRQLEDAESQVSQLSKIKISLTQQLEDTKRLADEEARE 1121
Score = 79.7 bits (195), Expect = 8e-13
Identities = 81/418 (19%), Positives = 183/418 (43%), Gaps = 25/418 (5%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L +Q+ E ++++ + + LE K +L A LE+++ L ++ KV +L + +E
Sbjct: 1308 LLDQIGEGGRNIHEIEKSRKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQE 1367
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ ++ +EE N ++ Q +D ++ +E E + +A ++++ A + ++
Sbjct: 1368 IDRRIQEKEEEFENTR------KNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINEL 1421
Query: 3451 KGDVLDKVDEATM-LQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+ LD ++A Q + R +++ + A+E+ Q + EQ R+ L +
Sbjct: 1422 E-IALDHANKANAEAQKNIKRYQQQLKDVQSALEEEQRARDDA-REQLGISERRANALQN 1479
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL-- 3801
++E+ + Q ++ + QA+QE +D +++ + A A I ++ E+ L + ++L
Sbjct: 1480 ELEESRTLLEQADRGRRQAEQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDE 1539
Query: 3802 ----AESDEHKRT--------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
A++ E K L D+L +D ++R+ E +Q RL A
Sbjct: 1540 LLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAESN 1599
Query: 3946 XXXXXXXXXXXTRLKIANIN------RARQLEDEKNALLDEKEEAE-GLRAHLEKEIHAA 4104
++ + + R + +KN E+ E ++ +++ H
Sbjct: 1600 ALKGGKKAIQKLEQRVRELESELDSEQRRHADAQKNLRKSERRIKELTFQSEEDRKNHER 1659
Query: 4105 RQGAGEARRKAEESVNQQLEELRK---KNLRDVEHLQKQLEESEVAKERILQSKKKIQ 4269
Q + ++ ++ +Q+EE + NL Q++LEE+E + Q+ K +
Sbjct: 1660 MQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADIAEQAATKFR 1717
Score = 53.9 bits (128), Expect = 5e-05
Identities = 62/408 (15%), Positives = 157/408 (38%), Gaps = 12/408 (2%)
Frame = +1
Query: 2533 QVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAE 2712
++ ++ + A+ DEL+A E + E + E K+ + +E + +++++ + + E
Sbjct: 1321 EIEKSRKRLEAEKDELQAALE---EAEAALEQEENKVLRAQLELSQVRQEIDRRIQEKEE 1377
Query: 2713 LDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXX 2892
+ + + ++ M+ L ++K + +
Sbjct: 1378 ------EFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKA 1431
Query: 2893 XXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHG 3072
+ Q Q A D L +L + +
Sbjct: 1432 NAEAQKNIKRYQQQLKDVQSALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQA 1491
Query: 3073 VKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQL 3252
+ + + E +L + + LN + + KRKL +EL+ L E + + + +
Sbjct: 1492 DRGRRQAEQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDELLNEAKNSEEKA 1551
Query: 3253 MKR-------DEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELRED-METERNARNKA 3408
K +EL+ + + +++Q++++Q +DE + ++ + A K
Sbjct: 1552 KKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAESNALKGGKKAIQKL 1611
Query: 3409 EMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQ 3588
E RE+ ++L+ + D + + + ++ E++Q ++ K++++
Sbjct: 1612 EQRVRELESELDSEQRRHADAQKNLRKSERRIKELTFQSEEDRKNHERMQDLVD-KLQQK 1670
Query: 3589 KAKFSRQVEELHD----QIEQHKKQRSQLEKQQNQADQERADMAQEIA 3720
+ RQ+EE + + + +K + +LE+ + ERAD+A++ A
Sbjct: 1671 IKTYKRQIEEAEEIAALNLAKFRKAQQELEEAE-----ERADIAEQAA 1713
>gi|189030|gb|AAA61765.1| nonmuscle myosin heavy chain-A
Length = 715
Score = 946 bits (2446), Expect = 0.0
Identities = 469/725 (64%), Positives = 571/725 (78%), Gaps = 8/725 (1%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTI 192
+YL V + + +P A WA +KL WVP GF S+K E + VELV+ ++V +
Sbjct: 8 KYLYVDKNFINNPLAQADWAAKKLVWVPSDKSGFEPASLKEEVGERGHVELVENGKKVKV 67
Query: 193 SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKL 372
++DD+QK NPPKF K+EDM+ELT LNEASVLHNLK+RYYS LIYTYSGLFCVVINPYK L
Sbjct: 68 NKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNL 127
Query: 373 PIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKV 552
PIYSE+++E +KGKKRHEMPPHI+AI DTAYRSM+Q+REDQSILCTGESGAGKTENTKKV
Sbjct: 128 PIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKV 187
Query: 553 IQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKND 732
IQYLA+VA + ++K GELE QLLQANPILEAFGN+KTVKND
Sbjct: 188 IQYLAYVASSHKSKKDQ-----------------GELERQLLQANPILEAFGNAKTVKND 230
Query: 733 NSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKS 912
NSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA++ER+FHIFY +L G K+
Sbjct: 231 NSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKT 290
Query: 913 EYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLG 1092
+ LLE + YRFL N +T+P D F T+ +MRIMG ++E ++RV+S VL LG
Sbjct: 291 DLLLEPYNKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLG 350
Query: 1093 NLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQA 1272
N+ F +E+ +DQA + D+ QKV HLLG+ V + + L PRIKVGR++V KAQ +EQA
Sbjct: 351 NIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQA 410
Query: 1273 EFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICIN 1452
+FA+EA+AKA+YER+F+WLV RINK+LD+T RQGASFIGILDIAGFEIFD+NSFEQ+CIN
Sbjct: 411 DFAIEALAKATYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCIN 470
Query: 1453 YTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPM---GVLALLDE 1623
YTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP IDLIEKP G+LALLDE
Sbjct: 471 YTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDE 530
Query: 1624 ECLFPKANDKSFVEKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMD 1800
EC FPKA DKSFVEK+ + HPKF P ++ K+ F ++HYAG+VDY AD+WLMKNMD
Sbjct: 531 ECWFPKATDKSFVEKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMD 590
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQLH 1968
PLN+N+ L+ S+D FV+ +WKD + G+ A M+ETA ++RKGMFRTV QL+
Sbjct: 591 PLNDNIATLLHQSSDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLY 650
Query: 1969 KEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPN 2148
KEQL KLM +LRNT+P+FVRCIIPNHEKK+GK++ +LVL+QLRCNGVLEGIRICRQGFPN
Sbjct: 651 KEQLAKLMASLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPN 710
Query: 2149 RVPFQ 2163
RV FQ
Sbjct: 711 RVVFQ 715
>gi|127774|sp|P08799|MYS2_DICDI Myosin II heavy chain, non muscle
gi|84128|pir||A26655 myosin heavy chain [similarity] - slime mold
(Dictyostelium discoideum)
gi|167835|gb|AAA33227.1| myosin heavy chain
Length = 2116
Score = 944 bits (2439), Expect = 0.0
Identities = 632/1958 (32%), Positives = 1019/1958 (51%), Gaps = 52/1958 (2%)
Frame = +1
Query: 13 QYLQVQRAAVADPATLAAWAQRKLCWVPDQNE--GFLIGSIKRETNDEVLVELVDTSRQV 186
+YL+V++ +D L +R + + PD E + G I ET+D + VD +
Sbjct: 13 KYLKVKQGD-SDLFKLTVSDKRYIWYNPDPKERDSYECGEIVSETSDSFTFKTVD-GQDR 70
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
+ +DD + NP KFD +EDMSEL+YLNE +V HNL+ RY LIYTYSGLF V +NP+K
Sbjct: 71 QVKKDDANQRNPIKFDGVEDMSELSYLNEPAVFHNLRVRYNQDLIYTYSGLFLVAVNPFK 130
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
++PIY++++++ FKG++R+E+ PHIFAI+D AYRSML +R++QS+L TGESGAGKTENTK
Sbjct: 131 RIPIYTQEMVDIFKGRRRNEVAPHIFAISDVAYRSMLDDRQNQSLLITGESGAGKTENTK 190
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVIQYLA VAG RN++ N G LE Q+LQANPILEAFGN+KT +
Sbjct: 191 KVIQYLASVAG--RNQA----------------NGSGVLEQQILQANPILEAFGNAKTTR 232
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
N+NSSRFGKFI I F+ +G+ISGA+I+ YLLEKSRV+ Q++ ER++HIFYQ+L G +A+E
Sbjct: 233 NNNSSRFGKFIEIQFNNAGFISGASIQSYLLEKSRVVFQSETERNYHIFYQLLAGATAEE 292
Query: 907 KSEYLLEGVDNYRFLVNRG-ITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVL 1083
K L G +++ +L G + + V D +EF T +M I+GF+ +E SI ++++ +L
Sbjct: 293 KKALHLAGPESFNYLNQSGYVDIKGVSDSEEFKITRQAMDIVGFSQEEQMSIFKIIAGIL 352
Query: 1084 LLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQ 1263
LGN++F ++ + A+L+D + + G+ L+KA + PRI GR+ V + N
Sbjct: 353 HLGNIKF-EKGAGEGAVLKDKTALNAASTVFGVNPSVLEKALMEPRILAGRDLVAQHLNV 411
Query: 1264 EQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQI 1443
E++ + +A+ KA Y RLF WLV +IN L + + A FIG+LDI+GFEIF +NSFEQ+
Sbjct: 412 EKSSSSRDALVKALYGRLFLWLVKKINNVLCQERK--AYFIGVLDISGFEIFKVNSFEQL 469
Query: 1444 CINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIE--KPMGVLALL 1617
CINYTNEKLQQ FN+ MF LEQEEY +E I W FIDFGLD Q TIDLI+ +P G+LALL
Sbjct: 470 CINYTNEKLQQFFNHHMFKLEQEEYLKEKINWTFIDFGLDSQATIDLIDGRQPPGILALL 529
Query: 1618 DEECLFPKANDKSFVEKLQKTHNKHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNM 1797
DE+ +FP A D + + KL +K SK+ F V HYAG+V Y WL KN
Sbjct: 530 DEQSVFPNATDNTLITKLHSHFSKKNAKYEEPRFSKTEFGVTHYAGQVMYEIQDWLEKNK 589
Query: 1798 DPLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGM-FRTVSQLHKE 1974
DPL +++ ++S+D V ++ D A R++KG F TV+ +KE
Sbjct: 590 DPLQQDLELCFKDSSDNVVTKLFNDPNIAS-------------RAKKGANFITVAAQYKE 636
Query: 1975 QLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRV 2154
QL LM TL T+PHFVRCIIPN+++ K+ +VL+QLRCNGVLEGIRI R+GFPNR+
Sbjct: 637 QLASLMATLETTNPHFVRCIIPNNKQLPAKLEDKVVLDQLRCNGVLEGIRITRKGFPNRI 696
Query: 2155 PFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLE 2334
+ +F RY +L P+V P++ D +++ ++ L+ID YR G +K+FFR G LA +E
Sbjct: 697 IYADFVKRYYLLAPNV-PRDAEDSQKATDAVLKHLNIDPEQYRFGITKIFFRAGQLARIE 755
Query: 2335 EERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFT 2514
E R+ +++ +I QA RG+++R++Y N AY+ ++W WW+LF+
Sbjct: 756 EAREQRISEIIKAIQAATRGWIARKVYKQAREHTVAARIIQQNLRAYIDFKSWPWWKLFS 815
Query: 2515 KVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQE 2694
K +PLL+ + EI+ K+ E+ K L + EK L +Q QL+ E
Sbjct: 816 KARPLLKRRNFEKEIKEKEREILELKSNLTDSTTQKDKLEKSLKDTESNVLDLQRQLKAE 875
Query: 2695 SENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXX 2874
E + D + L+ + +ELE V DM L +R E VRD
Sbjct: 876 KETLKAMYDSKDALEAQKRELEIRVEDMESELDEKKLALENLQNQKRSVEEKVRDLEEEL 935
Query: 2875 XXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHE 3054
K ++ D LT E
Sbjct: 936 QEEQKLRNTLEKLKKKYEEELEEMKRVNDGQSDTISRLEKIKDELQKEVEELTESF--SE 993
Query: 3055 ERAKHGV--KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL-AEKMG 3225
E GV K + RL+++L +L L+ E + KSEL + K+KL EL+ ++ L AE
Sbjct: 994 ESKDKGVLEKTRVRLQSELDDLTVRLDSETKDKSELLRQKKKLEEELKQVQEALAAETAA 1053
Query: 3226 KV--EELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNAR 3399
K+ E N +L EL +++ E + ++K + +++ + + +++ E+ R
Sbjct: 1054 KLAQEAANKKLQGEYTELNE---KFNSEVTARSNVEKSKKTLESQLVAVNNELDEEKKNR 1110
Query: 3400 NKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKI 3579
+ E ++ + A LE++K + E L DL +++ ++ A + I ++Q T+ K+
Sbjct: 1111 DALEKKKKALDAMLEEMKDQLESTGGEKKSLYDLKVKQESDMEALRNQISELQSTI-AKL 1169
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKR 3759
E+ K+ +V L ++E + +S +EKQ+ + + + D + ++A A++ +DK +
Sbjct: 1170 EKIKSTLEGEVARLQGELEAEQLAKSNVEKQKKKVELDLEDKSAQLAEETAAKQALDKLK 1229
Query: 3760 KIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAX 3939
K E L E+Q L+E++ + ++L E E+ A ++++
Sbjct: 1230 KKLEQELSEVQTQLSEANNKNVNSDSTNKHLETSFNNLKLELEAEQKAKQALEKKRLGLE 1289
Query: 3940 XXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAG 4119
+ K +N R LE E + L D+ EE + + + +
Sbjct: 1290 SELKHVNEQLEEEKKQKESNEKRKVDLEKEVSELKDQIEEEVASKKAVTEAKNKKESELD 1349
Query: 4120 EARRKAEESVN------QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELE 4281
E +R+ + V+ +QL+ L+ KN E L+ EE+E +R +SKKK + +LE
Sbjct: 1350 EIKRQYADVVSSRDKSVEQLKTLQAKN----EELRNTAEEAEGQLDRAERSKKKAEFDLE 1405
Query: 4282 DSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLN 4461
++ LE A +EK KK E+ + + L D +S E + ++ L
Sbjct: 1406 EAVKNLEEETAKKVKAEKAMKKAETDYR----STKSELDDAKNVSSE---QYVQIKRLNE 1458
Query: 4462 EVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEE 4641
E+ ++ LEE+D S + + + S + + AK E + ++ V++ E
Sbjct: 1459 ELSELRSVLEEADERCNSAIKAKKTAESALESLKDEIDAANNAKAKAERKSKELEVRVAE 1518
Query: 4642 LEDNLQ-----IAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENEL 4806
LE++L+ + + + + L++ DR ++ ++++E ++ KQ DLE ++
Sbjct: 1519 LEESLEDKSGTVNVEFIRKKDAEIDDLRARLDRETESR-IKSDEDKKNTRKQFADLEAKV 1577
Query: 4807 ENEKRGKSGAVSHRKKIENQIGELEQQLE-------------------VANRLKEEYXXX 4929
E +R +KK+E+ I +L QL+ +A R E
Sbjct: 1578 EEAQREVVTIDRLKKKLESDIIDLSTQLDTETKSRIKIEKSKKKLEQTLAERRAAEEGSS 1637
Query: 4930 XXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLRE-------ANEGL 5088
+ E +E R + A L +++K +++ AE ++++E A + L
Sbjct: 1638 KAADEEIRKQVWQEVDELRAQLDSERAALNASEKKIKSLVAEVDEVKEQLEDEILAKDKL 1697
Query: 5089 MQARKQXXXXXXXXXXXRAKGGGISSE---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQ 5259
++A++ + SE KRRL ++ + +
Sbjct: 1698 VKAKRALEVELEEVRDQLEEEEDSRSELEDSKRRLTTEVEDIKKKYDAEVEQNTKLDEAK 1757
Query: 5260 RKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAAL 5439
+K ++ + L E+ ++E K+ LE N D+ AK+ + E +SRA
Sbjct: 1758 KKLTDDVDTLKKQLEDEKKKLNESERAKKRLESENEDFLAKL-DAEVKNRSRAEKDRKKY 1816
Query: 5440 EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKN 5619
E ++ + +LN E KT A +LE ++++ + E E+ QA + + +
Sbjct: 1817 EKDLKDTKYKLNDEAATKTQTEIGAAKLEDQIDELRSKLEQEQAKATQADKSKKTLEGEI 1876
Query: 5620 RNLRRQL-DEAEDEMSRERTKHRNVQREADDLLDANEQ 5730
NLR Q+ DE + +M E+ K R ++ E ++L + E+
Sbjct: 1877 DNLRAQIEDEGKIKMRLEKEK-RALEGELEELRETVEE 1913
Score = 191 bits (486), Expect = 1e-46
Identities = 215/930 (23%), Positives = 408/930 (43%), Gaps = 27/930 (2%)
Frame = +1
Query: 3034 TQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLA 3213
TQL + + + LE + L+ +L E++ K LE+ + L +EL+ + L
Sbjct: 1241 TQLSEANNKNVNSDSTNKHLETSFNNLKLELEAEQKAKQALEKKRLGLESELKHVNEQLE 1300
Query: 3214 EKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERN 3393
E+ K ++ +N+ K D ++K++ +++ I+E +
Sbjct: 1301 EE--KKQKESNEKRKVD-------------------LEKEVSELKDQIEEEVASKKAVTE 1339
Query: 3394 ARNKAEMTRREVVAQLEKVKGDVLDKVDEAT-MLQDLMSRKDEEVNATKRAIEQIQHTME 3570
A+NK E E+ Q DV+ D++ L+ L ++ +E N + A Q+
Sbjct: 1340 AKNKKESELDEIKRQY----ADVVSSRDKSVEQLKTLQAKNEELRNTAEEAEGQLD---- 1391
Query: 3571 GKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEI--ALLQASRAD 3744
+ E K K +EE +E+ ++ + EK +A+ + E+ A +S
Sbjct: 1392 -RAERSKKKAEFDLEEAVKNLEEETAKKVKAEKAMKKAETDYRSTKSELDDAKNVSSEQY 1450
Query: 3745 IDKKRKIHEAHLMEIQANLAESDEH-------KRTLIDQLERSRDELDHLNRVREEEEHA 3903
+ KR E L E+++ L E+DE K+T LE +DE+D N + + E
Sbjct: 1451 VQIKRLNEE--LSELRSVLEEADERCNSAIKAKKTAESALESLKDEIDAANNAKAKAERK 1508
Query: 3904 FANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEK---NALLDEKEEAE--G 4068
++ R+A LED+ N K++AE
Sbjct: 1509 SKELEVRVA------------------------ELEESLEDKSGTVNVEFIRKKDAEIDD 1544
Query: 4069 LRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERIL 4248
LRA L++E E+R K++E +K + L+ ++EE++ I
Sbjct: 1545 LRARLDRET--------ESRIKSDED--------KKNTRKQFADLEAKVEEAQREVVTID 1588
Query: 4249 QSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELR 4428
+ KKK++ ++ D S +L+ S EK +KK E +AE R A + + A +E+R
Sbjct: 1589 RLKKKLESDIIDLSTQLDTETKSRIKIEKSKKKLEQTLAERRAAEEGS---SKAADEEIR 1645
Query: 4429 DRE-TRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLE 4605
+ V L ++D + L S++ +SL E+ + +D +L KAKR+LE
Sbjct: 1646 KQVWQEVDELRAQLDSERAALNASEKKIKSLVAEVDEVKEQLEDEILAKDKLVKAKRALE 1705
Query: 4606 AELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQI 4785
EL ++R Q+EE ED+ ED++ RL + +K + D + ++ + +E ++ L +
Sbjct: 1706 VELEEVRDQLEEEEDSRSELEDSKRRLTTEVEDIKKKYDAEV-EQNTKLDEAKKKLTDDV 1764
Query: 4786 RDLENELENEKRGKSGAVSHRKKIENQIGELEQQL--EVANRLKEEYXXXXXXXXXXXXE 4959
L+ +LE+EK+ + + +K++E++ + +L EV NR + E +
Sbjct: 1765 DTLKKQLEDEKKKLNESERAKKRLESENEDFLAKLDAEVKNRSRAEKDRKKYEKDLKDTK 1824
Query: 4960 YQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXX 5139
Y++ E A + + +I A E ++ R +L + QA K
Sbjct: 1825 YKLNDEAATKTQTEIGAAKLEDQ-----IDELRSKLEQEQAKATQADKSKKTLEGEIDNL 1879
Query: 5140 RAK---GGGIS---SEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDL 5301
RA+ G I +EKR LE ++ + + + A +R +++LE +L
Sbjct: 1880 RAQIEDEGKIKMRLEKEKRALEGELEELRETVEEAEDSKSEAEQSKRLVELELEDARRNL 1939
Query: 5302 SMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVE 5481
E + E K +L+R + K ++ E ES A++ + LEA++ L Q++ E
Sbjct: 1940 QKEIDAKEIAEDAKSNLQREIVEAKGRLEE-ESIARTNSDRSRKRLEAEIDALTAQVDAE 1998
Query: 5482 GQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEM 5661
+ K + +++E L + ++F + ++ + KE L L+ + +R EA DE
Sbjct: 1999 QKAKNQQIKENKKIETELKEYRKKFGESEKT--KTKEFLVVEKLET-DYKRAKKEAADEQ 2055
Query: 5662 SRERTKHRNVQREADD---LLDANEQLTRE 5742
+ T ++++ + L DA ++L R+
Sbjct: 2056 QQRLTVENDLRKHLSEISLLKDAIDKLQRD 2085
Score = 177 bits (450), Expect = 2e-42
Identities = 180/903 (19%), Positives = 390/903 (42%), Gaps = 20/903 (2%)
Frame = +1
Query: 3100 QLHELEQDLNRERQYKSELEQHKRKLL---AELEDS---KDHLAEKMGKVE----ELNNQ 3249
+L + L + R ++ E+++ +R++L + L DS KD L + + E +L Q
Sbjct: 812 KLFSKARPLLKRRNFEKEIKEKEREILELKSNLTDSTTQKDKLEKSLKDTESNVLDLQRQ 871
Query: 3250 LMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREV 3429
L E L+ D A ++ ++ DM++ +DE + +E +N + E R++
Sbjct: 872 LKAEKETLKAMYDSKDALEAQKRELEIRVEDMESELDEKKLALENLQNQKRSVEEKVRDL 931
Query: 3430 VAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQ 3609
+L+ ++ L+ L + +EE+ KR + T+ ++E+ K + ++
Sbjct: 932 EEELQ-------EEQKLRNTLEKLKKKYEEELEEMKRVNDGQSDTI-SRLEKIKDELQKE 983
Query: 3610 VEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEI 3789
VEEL + + K + LEK + + E D+ + ++++ +++K E L ++
Sbjct: 984 VEELTESFSEESKDKGVLEKTRVRLQSELDDLTVRLDSETKDKSELLRQKKKLEEELKQV 1043
Query: 3790 QANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQR-------RLATAXXXX 3948
Q LA K ++ + E LN E A +N+++ +L
Sbjct: 1044 QEALAAETAAKLAQEAANKKLQGEYTELNEKFNSEVTARSNVEKSKKTLESQLVAVNNEL 1103
Query: 3949 XXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEAR 4128
+ K A +++D+ + EK+ L+ E ++ A R E
Sbjct: 1104 DEEKKNRDALEKKKKALDAMLEEMKDQLESTGGEKKSLYDLKVKQESDMEALRNQISEL- 1162
Query: 4129 RKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENV 4308
+S +LE+++ +V LQ +LE ++AK + + KKK++ +LED S +L
Sbjct: 1163 ----QSTIAKLEKIKSTLEGEVARLQGELEAEQLAKSNVEKQKKKVELDLEDKSAQLAEE 1218
Query: 4309 RASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHL 4488
A+ + +K +KK E +++E + + +A + ET +L E++ ++
Sbjct: 1219 TAAKQALDKLKKKLEQELSEVQTQLSEANNKNVNSDSTNKHLETSFNNLKLELEAEQKAK 1278
Query: 4489 EESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAE 4668
+ ++ R L+ EL+ ++ K EK K LE E+++++ Q+EE + +
Sbjct: 1279 QALEKKRLGLESELKHVNEQLEEEKKQKESNEKRKVDLEKEVSELKDQIEEEVASKKAVT 1338
Query: 4669 DARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHR 4848
+A+ + E +K + +S++D ++ E+ + L + +L N E + A +
Sbjct: 1339 EAKNKKESELDEIKRQYADVVSSRD-KSVEQLKTLQAKNEELRNTAEEAEGQLDRAERSK 1397
Query: 4849 KKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREAD 5028
KK E + E + LE K + + E ++A+ + ++ +
Sbjct: 1398 KKAEFDLEEAVKNLEEETAKKVKAEKAMKKAETDYRSTKSELDDAKNVSSEQYVQIKRLN 1457
Query: 5029 RKFRAVEAEREQLREANEGLMQARK--QXXXXXXXXXXXRAKGGGISSEEK-RRLEAKIA 5199
+ + + E+ E ++A+K + A +E K + LE ++A
Sbjct: 1458 EELSELRSVLEEADERCNSAIKAKKTAESALESLKDEIDAANNAKAKAERKSKELEVRVA 1517
Query: 5200 QXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKA 5379
+ + ++ RK +++ + L E K++ +K++ + D +A
Sbjct: 1518 ELEESLEDKSGT--VNVEFIRKKDAEIDDLRARLDRETESRIKSDEDKKNTRKQFADLEA 1575
Query: 5380 KITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFE 5559
K+ E + + R + LE+ + L QL+ E + + ++ ++LE+ L + E
Sbjct: 1576 KVEEAQREVVTIDRLK-KKLESDIIDLSTQLDTETKSRIKIEKSKKKLEQTLAERRAAEE 1634
Query: 5560 DEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTR 5739
+A ++ E+ ++ + LR QLD ++ K +++ E D++ EQL
Sbjct: 1635 GSSKAADE--EIRKQVWQEVDELRAQLDSERAALNASEKKIKSLVAEVDEV---KEQLED 1689
Query: 5740 ELM 5748
E++
Sbjct: 1690 EIL 1692
Score = 166 bits (419), Expect = 8e-39
Identities = 171/872 (19%), Positives = 380/872 (42%), Gaps = 31/872 (3%)
Frame = +1
Query: 3043 LDHEERAKHGVKAKGR-LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEK 3219
L+ E++AK ++ K LE++L + + L E++ K E+ K L E+ + KD + E+
Sbjct: 1271 LEAEQKAKQALEKKRLGLESELKHVNEQLEEEKKQKESNEKRKVDLEKEVSELKDQIEEE 1330
Query: 3220 MGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNAR 3399
+ + + K++ EL +Y + ++ +Q++ +Q +ELR E
Sbjct: 1331 VASKKAVTEAKNKKESELDEIKRQYADVVSSRDKSVEQLKTLQAKNEELRNTAEEAEGQL 1390
Query: 3400 NKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKI 3579
++AE ++++ LE+ ++ ++ + + M + + + +TK ++ ++ +
Sbjct: 1391 DRAERSKKKAEFDLEEAVKNLEEETAKKVKAEKAMKKAETDYRSTKSELDDAKNVSSEQY 1450
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKR 3759
+ K + + ++ EL +E+ ++ + K + A+ + EI ++A ++K
Sbjct: 1451 VQIK-RLNEELSELRSVLEEADERCNSAIKAKKTAESALESLKDEIDAANNAKAKAERKS 1509
Query: 3760 KIHEAHLMEIQANLAESD--------EHKRTLIDQLERSRDELDHLNRVREEEEHAFANM 3915
K E + E++ +L + K ID L R+R + + +R++ +E+ N
Sbjct: 1510 KELEVRVAELEESLEDKSGTVNVEFIRKKDAEIDDL-RARLDRETESRIKSDEDKK--NT 1566
Query: 3916 QRRLATAXXXXXXXXXXXXXXTRLKIAN----INRARQLEDEKNALLDEKEEAEGLRAHL 4083
+++ A RLK I+ + QL+ E + + ++ + L L
Sbjct: 1567 RKQFADLEAKVEEAQREVVTIDRLKKKLESDIIDLSTQLDTETKSRIKIEKSKKKLEQTL 1626
Query: 4084 EKEIHAARQGAGEAR-RKAEESVNQQLEELR-----------------KKNLRDVEHLQK 4209
E AA +G+ +A + + V Q+++ELR K + +V+ +++
Sbjct: 1627 A-ERRAAEEGSSKAADEEIRKQVWQEVDELRAQLDSERAALNASEKKIKSLVAEVDEVKE 1685
Query: 4210 QLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQK 4389
QLE+ +AK++++++K+ ++ ELE+ +LE S + E +++ +++ + +
Sbjct: 1686 QLEDEILAKDKLVKAKRALEVELEEVRDQLEEEEDSRSELEDSKRRLTTEVEDIKKKYDA 1745
Query: 4390 ALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKN 4569
+ + + + V +L +++ K+ L ES+R ++ L+ E +D ++ D KN
Sbjct: 1746 EVEQNTKLDEAKKKLTDDVDTLKKQLEDEKKKLNESERAKKRLESENEDFLAKLDAEVKN 1805
Query: 4570 VHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVE 4749
EK ++ E +L D + ++ + E +LE L+S+ ++ K +
Sbjct: 1806 RSRAEKDRKKYEKDLKDTKYKLNDEAATKTQTEIGAAKLEDQIDELRSKLEQE-QAKATQ 1864
Query: 4750 AEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXX 4929
A++ ++ L +I +L ++E+E + K ++ +E ++ EL + +E A K E
Sbjct: 1865 ADKSKKTLEGEIDNLRAQIEDEGKIKMRLEKEKRALEGELEELRETVEEAEDSKSE---- 1920
Query: 4930 XXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQX 5109
++E E+AR+ L +E D K A +A+ RE E + ++
Sbjct: 1921 ---AEQSKRLVELELEDARR------NLQKEIDAKEIAEDAKSNLQREIVEAKGRLEEES 1971
Query: 5110 XXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQI 5289
S ++RLEA+I Q I + +K + +L++
Sbjct: 1972 IARTN------------SDRSRKRLEAEIDALTAQVDAEQKAKNQQIKENKKIETELKEY 2019
Query: 5290 TTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQ 5469
K E +E+ DYK RA+ + A + + +E+
Sbjct: 2020 RKKFGESEKTKTK---EFLVVEKLETDYK------------RAKKEAADEQQQRLTVEND 2064
Query: 5470 LNVEGQEKTAANRAARRLEKRLNDTTQQFEDE 5565
L E + A +L++ + T ++ E E
Sbjct: 2065 LRKHLSEISLLKDAIDKLQRDHDKTKRELETE 2096
Score = 135 bits (339), Expect = 2e-29
Identities = 173/832 (20%), Positives = 340/832 (40%), Gaps = 51/832 (6%)
Frame = +1
Query: 2569 DDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQE-----------SENSAEL 2715
+ EL+ E+L + + NEK+ + E + +++Q+++E ++ +EL
Sbjct: 1289 ESELKHVNEQLEEEKKQKESNEKRKVDLEKEVSELKDQIEEEVASKKAVTEAKNKKESEL 1348
Query: 2716 DDIRGR-----------------LQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQM 2844
D+I+ + LQ +N+EL + +L + +
Sbjct: 1349 DEIKRQYADVVSSRDKSVEQLKTLQAKNEELRNTAEEAEGQLDRAERSKKKAEFDLEEAV 1408
Query: 2845 ETVRDXXXXXXXXXXXXXXXXXD----KTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXX 3012
+ + + D K+ +D + +
Sbjct: 1409 KNLEEETAKKVKAEKAMKKAETDYRSTKSELDDAKNVSSEQYVQIKRLNEELSE------ 1462
Query: 3013 XXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELE 3192
L + L + +ER +KAK E+ L L+ +++ K++ E+ ++L +
Sbjct: 1463 -----LRSVLEEADERCNSAIKAKKTAESALESLKDEIDAANNAKAKAERKSKELEVRVA 1517
Query: 3193 DSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELRE 3372
+ ++ L +K G V + K+D E+ R D E T ++
Sbjct: 1518 ELEESLEDKSGTVNV--EFIRKKDAEIDDLRARLDRE----------------TESRIKS 1559
Query: 3373 DMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQ 3552
D + + + A++ + AQ E V D L K E+ ++ DL ++ D E TK I
Sbjct: 1560 DEDKKNTRKQFADLEAKVEEAQREVVTIDRLKKKLESDII-DLSTQLDTE---TKSRI-- 1613
Query: 3553 IQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQ--NQADQERADMAQEIALL 3726
KIE+ K K + + E E K + ++Q + D+ RA + E A L
Sbjct: 1614 -------KIEKSKKKLEQTLAERRAAEEGSSKAADEEIRKQVWQEVDELRAQLDSERAAL 1666
Query: 3727 QASRADIDKKRKIHEAHLMEIQANLAES-------DEHKRTLIDQLERSRDELDHLNRVR 3885
AS +KK K A + E++ L + + KR L +LE RD+L+ R
Sbjct: 1667 NAS----EKKIKSLVAEVDEVKEQLEDEILAKDKLVKAKRALEVELEEVRDQLEEEEDSR 1722
Query: 3886 EEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAE 4065
E E + +RRL T ++ +I + E E+N LDE ++
Sbjct: 1723 SELE----DSKRRLTT------------------EVEDIKKKYDAEVEQNTKLDEAKK-- 1758
Query: 4066 GLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERI 4245
L ++ ++ + ++K ES E +K+ + E +L+ + R
Sbjct: 1759 ----KLTDDVDTLKKQLEDEKKKLNES-----ERAKKRLESENEDFLAKLDAEVKNRSRA 1809
Query: 4246 LQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQEL 4425
+ +KK +++L+D+ +L + A+ +E K E Q+ E R + L+++
Sbjct: 1810 EKDRKKYEKDLKDTKYKLNDEAATKTQTEIGAAKLEDQIDELR-----SKLEQEQAKATQ 1864
Query: 4426 RDRETRVLSLLNEVDIMKEHLEESDRV-------RRSLQQELQDSISNKDDFGKNVHELE 4584
D+ + L E+D ++ +E+ ++ +R+L+ EL++ ++ + E E
Sbjct: 1865 ADKSKKTLE--GEIDNLRAQIEDEGKIKMRLEKEKRALEGELEELRETVEEAEDSKSEAE 1922
Query: 4585 KAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLE---VTNQALKSESDRAISNKDVEAE 4755
++KR +E EL D R +++ D +IAEDA+ L+ V + E A +N D
Sbjct: 1923 QSKRLVELELEDARRNLQKEIDAKEIAEDAKSNLQREIVEAKGRLEEESIARTNSD---- 1978
Query: 4756 EKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLK 4911
R+ L +I L +++ E++ K+ + KKIE ++ E ++ + + K
Sbjct: 1979 RSRKRLEAEIDALTAQVDAEQKAKNQQIKENKKIETELKEYRKKFGESEKTK 2030
>gi|50757619|ref|XP_415580.1| PREDICTED: similar to myosin, heavy
polypeptide 7, cardiac muscle, beta; myosin heavy chain,
cardiac muscle, fetal [Gallus gallus]
Length = 1792
Score = 942 bits (2436), Expect = 0.0
Identities = 585/1748 (33%), Positives = 938/1748 (53%), Gaps = 76/1748 (4%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V E F+ G+I+ + +V V+ + +T+ D V NPPK+DKIEDM+ +T+L
Sbjct: 39 FVVHPKESFVKGTIQSKETGKVTVK-TEGGETLTVKEDQVFSMNPPKYDKIEDMAMMTHL 97
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 98 HEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVLAYRGKKRQEAPPHIFS 157
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
I+D AY+ ML +RE+QSIL TGESGAGKT NTK+VIQY A +A + K +
Sbjct: 158 ISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAASGEKKKEEQPGKMQ-- 215
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
G LE Q++ ANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G ++ A+IE
Sbjct: 216 ---------GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIE 266
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVD--NYRFLVNRGITLPNV 981
YLLEKSRV Q + ERS+HIFYQI+ E + LL + +Y+F+ IT+P++
Sbjct: 267 TYLLEKSRVTFQLKAERSYHIFYQIMSN-KKPELIDMLLITTNPYDYQFVSQGEITVPSI 325
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
+D +E +T +++ I+GF DE ++I ++ AV+ GNL+F Q+++ +QA V K
Sbjct: 326 NDQEELMATDSAIDILGFTPDEKTAIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADK 385
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+L+GL +L KA PR+KVG E+V K Q +Q AV A+AKA YE++F W+V RI
Sbjct: 386 AAYLMGLNSADLLKALCYPRVKVGNEYVTKGQTVQQVHNAVGALAKAVYEKMFLWMVVRI 445
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQEEY+
Sbjct: 446 NQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 504
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGIEW+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA D SF KL H K
Sbjct: 505 KEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNN 564
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P ++++HF++VHYAG VDY+ WL KN DPLNE V+GL Q S+ +A ++
Sbjct: 565 FQKPKPGKGKAEAHFSLVHYAGTVDYNISGWLEKNKDPLNETVIGLYQKSSVKTLALLFA 624
Query: 1870 DAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHE 2049
A G A G + + F+TVS L +E L KLMT LR+T PHFVRCIIPN
Sbjct: 625 SA--GGEAEASGGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 682
Query: 2050 KKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDG 2226
K G + LVL QLRCNGVLEGIRICR+GFP+RV + +F+ RY++L IP+ FID
Sbjct: 683 KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRVLYADFKQRYKVLNASAIPEGQFIDS 742
Query: 2227 KESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSR 2406
K++ K++ ++D+D Y+ G +KVFF+ G+L LEE RD KL LI QA+CRGFL R
Sbjct: 743 KKASEKLLGSIDVDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQARCRGFLMR 802
Query: 2407 RLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRA 2586
Y N +++ +++W W +LF K+KPLL+ ++ E+ +E
Sbjct: 803 VEYQRMVERRESIFCIQYNVRSFMNVKHWPWMKLFFKIKPLLKSAESEKEMANMKEEFEK 862
Query: 2587 TKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYI 2766
TKE L K E +E E+K+ ++ E+ +Q Q+Q E+++ A+ ++ +L +LE
Sbjct: 863 TKEELAKSEAKRKELEEKMVSLLQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAK 922
Query: 2767 VNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXX 2946
+ ++ +R +RK + + +K +
Sbjct: 923 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 982
Query: 2947 XXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLH------ 3108
+ L E++ KAK +LE Q+
Sbjct: 983 TEEMAALDENIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDATLQH 1042
Query: 3109 ----------------ELEQDLNRERQYKSELEQHKRKLLAELED--------------- 3195
EL + ++ ++ K +LE+ K +L E++D
Sbjct: 1043 EATAVALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMESVSKAKASL 1102
Query: 3196 ------SKDHLAEKMGKVEE-------LNNQLMKRDEELQHQLTRYDEESANVTLMQKQM 3336
+D L+E K EE LN Q + E + +E+ A ++ + +
Sbjct: 1103 EKTCRALEDQLSEIKTKEEEHQRMINDLNAQRARLQTESGEYSRQVEEKDALISQLSRGK 1162
Query: 3337 RDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKD 3516
+ I+EL+ +E E A++ + + ++ ++ + LQ +S+ +
Sbjct: 1163 QAFTQQIEELKRHLEEEIKAKSALAHALQSARHDCDLLREQYEEEQEAKGELQRALSKAN 1222
Query: 3517 EEVN--ATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQ 3690
EV TK + IQ T E +EE K K ++++++ + +E + + LEK + +
Sbjct: 1223 SEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQN 1280
Query: 3691 ERADMAQEIALLQASRADIDKKRKIHEAHLM-------EIQANLAESDEHKRTLIDQLER 3849
E D+ ++ A+ A +DKK+K + L E Q L S + R+L +L +
Sbjct: 1281 EVEDLMIDVERANAACAALDKKQKNFDKILSEWKQKYEETQTELEASQKESRSLSTELFK 1340
Query: 3850 SR----DELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQ 4017
+ + LDHL ++ E + N+Q+ ++ ++K +Q
Sbjct: 1341 MKNAYEESLDHLETLKRENK----NLQQEISDLTEQIAEGGKAIHELEKVK-------KQ 1389
Query: 4018 LEDEKNALLDEKEEAEGLRAHLEKEIHAAR----QGAGEARRKAEESVNQQLEELRKKNL 4185
+E EK+ + EEAE H E +I + Q E RK E ++++++L++ +L
Sbjct: 1390 IEQEKSEIQAALEEAEASLEHEEGKILRLQLELNQVKSEIDRKIAEK-DEEIDQLKRNHL 1448
Query: 4186 RDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMA 4365
R VE +Q L+ ++ L+ KKK++ +L + ++L + +++K + + +
Sbjct: 1449 RIVESMQSTLDAEIRSRNEALRLKKKMEGDLNEMEIQLSHANRVAAEAQKNLRNTQGVLK 1508
Query: 4366 EERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSIS 4545
+ ++ + AL ++ + +++ E R L E++ ++ LE+++R R+ +QEL D+
Sbjct: 1509 DTQIHLDDALRTQEDLKEQVAMVERRANLLQAEIEELRAALEQTERSRKVAEQELMDASE 1568
Query: 4546 NKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDR 4725
L K+ LE +++ ++ +ME+ + AE+ + + +T+ A+ +E +
Sbjct: 1569 RVQLLHTQNTSLINTKKKLETDISQIQSEMEDTIQEARNAEE-KAKKAITDAAMMAEELK 1627
Query: 4726 AISNKDVEAEEKRRGLLKQIRDLENEL-ENEKRGKSGAVSHRKKIENQIGELEQQLEVAN 4902
+ E ++ L + ++DL+ L E E+ G +K+E ++ ELE +++
Sbjct: 1628 KEQDTSAHLERMKKNLDQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVDSEQ 1687
Query: 4903 RLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLRE-AN 5079
+ E E + EE R+ + L+ + K ++ + + E+ E +N
Sbjct: 1688 KRSAEAVKGVRKYERRVKELTYQSEEDRKNILRLQDLVDKLQMKVKSYKRQAEEAEELSN 1747
Query: 5080 EGLMQARK 5103
L + RK
Sbjct: 1748 VNLSKFRK 1755
Score = 300 bits (769), Expect = 2e-79
Identities = 222/903 (24%), Positives = 430/903 (47%), Gaps = 13/903 (1%)
Frame = +1
Query: 3040 LLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKL---LAELEDSKDHL 3210
L D EER +K K +LE ++ E+ + E + +EL KRKL +EL+ D L
Sbjct: 902 LADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL 961
Query: 3211 AEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDM-QTTIDELREDMETE 3387
+ KVE+ + + + L ++ DE A +T +K +++ Q T+D+L+ +
Sbjct: 962 ELTLAKVEKEKHATENKVKNLTEEMAALDENIAKLTKEKKALQEAHQQTLDDLQAE---- 1017
Query: 3388 RNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTM 3567
+ V L K K + +VD+AT+ + AT A+ +
Sbjct: 1018 -----------EDKVNTLTKAKTKLEQQVDDATLQHE----------ATAVALRK----- 1051
Query: 3568 EGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADI 3747
K + EL +QI+ ++ + +LEK++++ E D+A + + ++A +
Sbjct: 1052 ---------KHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMESVSKAKASL 1102
Query: 3748 DKKRKIHEAHLMEIQANLAESDEHKRTLID---QLERSRDELDHLNRVREEEEHAFANMQ 3918
+K + E L EI+ + +EH+R + D Q R + E +R EE++ + +
Sbjct: 1103 EKTCRALEDQLSEIKT---KEEEHQRMINDLNAQRARLQTESGEYSRQVEEKDALISQLS 1159
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
R + K A + + + + L ++ EE + + L++ +
Sbjct: 1160 RGKQAFTQQIEELKRHLEEEIKAKSALAHALQSARHDCDLLREQYEEEQEAKGELQRALS 1219
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKER---ILQSKKKIQ 4269
A + R K E Q+ EEL + + + LQ E E + + ++K+++Q
Sbjct: 1220 KANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQ 1279
Query: 4270 QELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL 4449
E+ED +++E A+ +K+QK F+ ++E + ++ + +A +E R T +
Sbjct: 1280 NEVEDLMIDVERANAACAALDKKQKNFDKILSEWKQKYEETQTELEASQKESRSLSTELF 1339
Query: 4450 SLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRV 4629
+ N + +HLE R ++LQQE+ D + GK +HELEK K+ +E E ++++
Sbjct: 1340 KMKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKAIHELEKVKKQIEQEKSEIQA 1399
Query: 4630 QMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELE 4809
+EE E +L+ E LRL++ +KSE DR I+ KD E ++ +R L+ + +++ L+
Sbjct: 1400 ALEEAEASLEHEEGKILRLQLELNQVKSEIDRKIAEKDEEIDQLKRNHLRIVESMQSTLD 1459
Query: 4810 NEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQ 4989
E R ++ A+ +KK+E + E+E QL ANR+ E + QI ++A +
Sbjct: 1460 AEIRSRNEALRLKKKMEGDLNEMEIQLSHANRVAAEAQKNLRNTQGVLKDTQIHLDDALR 1519
Query: 4990 AKEDIAALLREADRKFRAVEAEREQLREANEGLMQARK---QXXXXXXXXXXXRAKGGGI 5160
+ED+ + +R+ ++AE E+LR A E ++RK Q
Sbjct: 1520 TQEDLKEQVAMVERRANLLQAEIEELRAALEQTERSRKVAEQELMDASERVQLLHTQNTS 1579
Query: 5161 SSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAE 5340
K++LE I+Q A +K +KA + +L E+ + E
Sbjct: 1580 LINTKKKLETDISQIQSEMEDTIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERM 1639
Query: 5341 KQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARR 5520
K++L+++ +D + ++ E E A + Q+ LEA+V+ LE +++ E + A + R+
Sbjct: 1640 KKNLDQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVDSEQKRSAEAVKGVRK 1699
Query: 5521 LEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQRE 5700
E+R+ + T Q E++++ + ++L++K +K ++ +RQ +EAE+ + +K R +Q E
Sbjct: 1700 YERRVKELTYQSEEDRKNILRLQDLVDKLQMKVKSYKRQAEEAEELSNVNLSKFRKIQHE 1759
Query: 5701 ADD 5709
++
Sbjct: 1760 LEE 1762
Score = 112 bits (280), Expect = 1e-22
Identities = 108/586 (18%), Positives = 251/586 (42%), Gaps = 34/586 (5%)
Frame = +1
Query: 4057 EAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAK 4236
E+E A++++E ++ ++ K +E + + L++KN D++ LQ Q E +A
Sbjct: 848 ESEKEMANMKEEFEKTKEELAKSEAKRKELEEKMVSLLQEKN--DLQ-LQVQAEADSLAD 904
Query: 4237 -----ERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLD 4401
++++++K +++ ++++ + E+ + + +++K E + +E + + L
Sbjct: 905 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 964
Query: 4402 RDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHEL 4581
+ +E E +V +L E+ + E++ + + +++LQ+ Q ++ + V+ L
Sbjct: 965 LAKVEKEKHATENKVKNLTEEMAALDENIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1024
Query: 4582 EKAKRSLEAELNDMRVQME---------------ELEDNLQIAEDARLRLEVTNQALKSE 4716
KAK LE +++D +Q E EL + + + + +LE LK E
Sbjct: 1025 TKAKTKLEQQVDDATLQHEATAVALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKME 1084
Query: 4717 SDRAISNKDVEAEEKR------RGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGEL 4878
D SN + ++ K R L Q+ +++ + E +R + + R +++ + GE
Sbjct: 1085 IDDLASNMESVSKAKASLEKTCRALEDQLSEIKTKEEEHQRMINDLNAQRARLQTESGEY 1144
Query: 4879 EQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA----DRKFRAV 5046
+Q+E + L + E + EE +AK +A L+ A D
Sbjct: 1145 SRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKSALAHALQSARHDCDLLREQY 1204
Query: 5047 EAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXX 5226
E E+E E L +A + + E K++L ++
Sbjct: 1205 EEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAV 1264
Query: 5227 QSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKI----TEL 5394
+ C +++ Q ++E + D+ + ++++ ++ ++K K TEL
Sbjct: 1265 NAKCASLEKTKQRLQNEVEDLMIDVERANAACAALDKKQKNFDKILSEWKQKYEETQTEL 1324
Query: 5395 ESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRA 5574
E+ + + K Y E ++E R + L++ ++D T+Q + +A
Sbjct: 1325 EASQKESRSLSTELFKMKNAYEESLDHLE-----TLKRENKNLQQEISDLTEQIAEGGKA 1379
Query: 5575 NEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDL 5712
+ +++ ++ + ++ L+EAE + E K +Q E + +
Sbjct: 1380 IHELEKVKKQIEQEKSEIQAALEEAEASLEHEEGKILRLQLELNQV 1425
Score = 102 bits (254), Expect = 1e-19
Identities = 100/485 (20%), Positives = 208/485 (42%), Gaps = 17/485 (3%)
Frame = +1
Query: 2968 QDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYK 3147
++AY+ L ++ D E+ G KA +HELE+ K
Sbjct: 1342 KNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKA-------IHELEK-------VK 1387
Query: 3148 SELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQ 3327
++EQ K ++ A LE+++ L + GK+ L +L + E+ ++ DEE +
Sbjct: 1388 KQIEQEKSEIQAALEEAEASLEHEEGKILRLQLELNQVKSEIDRKIAEKDEE------ID 1441
Query: 3328 KQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMS 3507
+ R+ ++ ++ ++ E +RN+A ++++ L +++ + A Q +
Sbjct: 1442 QLKRNHLRIVESMQSTLDAEIRSRNEALRLKKKMEGDLNEMEIQLSHANRVAAEAQKNLR 1501
Query: 3508 RKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQAD 3687
+ T+ ++ T E ++EQ A R+ L +IE+ + Q E+ + A+
Sbjct: 1502 NTQGVLKDTQIHLDDALRTQED-LKEQVAMVERRANLLQAEIEELRAALEQTERSRKVAE 1560
Query: 3688 QERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRT------------- 3828
QE D ++ + LL + +K E + +IQ+ + ++ + R
Sbjct: 1561 QELMDASERVQLLHTQNTSLINTKKKLETDISQIQSEMEDTIQEARNAEEKAKKAITDAA 1620
Query: 3829 -LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANIN 4005
+ ++L++ +D HL R+++ + ++Q RL A + +I +
Sbjct: 1621 MMAEELKKEQDTSAHLERMKKNLDQTVKDLQLRLDEAEQLALKGG-------KKQIQKLE 1673
Query: 4006 -RARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQ--QLEELRK 4176
R R+LE E ++ ++K AE + K + + E ++EE +L++L
Sbjct: 1674 ARVRELEGEVDS--EQKRSAEAV-----KGVRKYERRVKELTYQSEEDRKNILRLQDLVD 1726
Query: 4177 KNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFES 4356
K V+ ++Q EE+E L +KIQ ELE++ + + + ++F S
Sbjct: 1727 KLQMKVKSYKRQAEEAEELSNVNLSKFRKIQHELEEAEERADIAESQVNKLRVKSREFHS 1786
Query: 4357 QMAEE 4371
+ EE
Sbjct: 1787 KKIEE 1791
Score = 100 bits (250), Expect = 3e-19
Identities = 118/601 (19%), Positives = 239/601 (39%), Gaps = 47/601 (7%)
Frame = +1
Query: 3055 ERAKHGVKAKGRLENQLHELEQDLNRER--------QYKSELEQHKRKLLAELEDSKDHL 3210
E+ + +AKG L+ L + ++ + R Q ELE+ K+KL L+D+++H+
Sbjct: 1202 EQYEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHV 1261
Query: 3211 AEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETER 3390
K L + E++ + + +A + K+ ++ + E ++ E +
Sbjct: 1262 EAVNAKCASLEKTKQRLQNEVEDLMIDVERANAACAALDKKQKNFDKILSEWKQKYEETQ 1321
Query: 3391 NARNKAEMTRREVVAQLEKVKGDVLDKVD-------EATMLQDLMSRKDEEVNATKRAIE 3549
++ R + +L K+K + +D E LQ +S E++ +AI
Sbjct: 1322 TELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKAIH 1381
Query: 3550 QIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQA----DQERADMAQEI 3717
+++ + +IE++K++ +EE +E + + +L+ + NQ D++ A+ +EI
Sbjct: 1382 ELEKVKK-QIEQEKSEIQAALEEAEASLEHEEGKILRLQLELNQVKSEIDRKIAEKDEEI 1440
Query: 3718 ALLQASRADIDKKRKIHEAHLMEIQANLAESDEH---KRTLIDQLERSRDELDHLNRVRE 3888
L+ + +I E+ + A + +E K+ + L +L H NRV
Sbjct: 1441 DQLKRNHL------RIVESMQSTLDAEIRSRNEALRLKKKMEGDLNEMEIQLSHANRVAA 1494
Query: 3889 EEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEG 4068
E + N Q L RA L+ E L E+ E
Sbjct: 1495 EAQKNLRNTQGVLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEIEELRAALEQTER 1554
Query: 4069 LRAHLEKEI----------HAARQGAGEARRKAEESVNQ-------------QLEELRKK 4179
R E+E+ H ++K E ++Q EE KK
Sbjct: 1555 SRKVAEQELMDASERVQLLHTQNTSLINTKKKLETDISQIQSEMEDTIQEARNAEEKAKK 1614
Query: 4180 NLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENV-RASHRDSEKRQKKFES 4356
+ D + ++L++ + + + KK + Q ++D + L+ + + + +K+ +K E+
Sbjct: 1615 AITDAAMMAEELKKEQDTSAHLERMKKNLDQTVKDLQLRLDEAEQLALKGGKKQIQKLEA 1674
Query: 4357 QMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQD 4536
++ E V + +R E RV L + E DR Q+L D
Sbjct: 1675 RVRELEGEVDSEQKRSAEAVKGVRKYERRVKELTYQ--------SEEDRKNILRLQDLVD 1726
Query: 4537 SISNK-DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKS 4713
+ K + + E E+ ++ ++ ++EE E+ IAE +L V ++ S
Sbjct: 1727 KLQMKVKSYKRQAEEAEELSNVNLSKFRKIQHELEEAEERADIAESQVNKLRVKSREFHS 1786
Query: 4714 E 4716
+
Sbjct: 1787 K 1787
Score = 100 bits (248), Expect = 6e-19
Identities = 136/741 (18%), Positives = 287/741 (38%), Gaps = 95/741 (12%)
Frame = +1
Query: 3802 AESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXT 3981
AES++ + ++ E++++EL R+E E ++ +
Sbjct: 847 AESEKEMANMKEEFEKTKEELAKSEAKRKELEEKMVSLLQE------------------- 887
Query: 3982 RLKIANINRARQLEDEKNALLDEKEEAEGL---RAHLEKEIHAARQGAGEARRKAEESVN 4152
+ Q++ E ++L D +E + L + LE +I + R + EE +N
Sbjct: 888 -----KNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTE-----RAEDEEEIN 937
Query: 4153 QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMEL----ENVRASH 4320
+L ++K + L+K +++ E+ ++ + K + ++++ + E+ EN+
Sbjct: 938 AELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAALDENIAKLT 997
Query: 4321 RDS----EKRQKKFESQMAEE-------------RVAVQKALLDRDAMSQELRDRETRVL 4449
++ E Q+ + AEE V A L +A + LR +
Sbjct: 998 KEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDATLQHEATAVALRKKHADST 1057
Query: 4450 SLLNE-VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMR 4626
+ L E +D ++ ++ ++ + L+ E+ D SN + K LEK R+LE +L++++
Sbjct: 1058 AELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMESVSKAKASLEKTCRALEDQLSEIK 1117
Query: 4627 VQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRG---LLKQIRDLE 4797
+ EE + + R RL+ + E R + KD + RG +QI +L+
Sbjct: 1118 TKEEEHQRMINDLNAQRARLQTES----GEYSRQVEEKDALISQLSRGKQAFTQQIEELK 1173
Query: 4798 NELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIE-- 4971
LE E + KS + + L +Q E K E +++ +
Sbjct: 1174 RHLEEEIKAKSALAHALQSARHDCDLLREQYEEEQEAKGELQRALSKANSEVAQWRTKYE 1233
Query: 4972 ------CEEARQAKEDIAALLREADRKFRAVEAE-------REQLREANEGLMQARKQXX 5112
EE +AK+ +A L++A+ AV A+ +++L+ E LM ++
Sbjct: 1234 TDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERAN 1293
Query: 5113 XXXXXXXXXRAKGGGISSE-----------------EKRRLEAKIAQXXXXXXXXQSNCE 5241
+ I SE E R L ++ + + E
Sbjct: 1294 AACAALDKKQKNFDKILSEWKQKYEETQTELEASQKESRSLSTELFKMKNAYEESLDHLE 1353
Query: 5242 LAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRA- 5418
+ + Q ++ +T ++ + E K+ +E+ + +A + E E+ +
Sbjct: 1354 TLKRENKNLQQEISDLTEQIAEGGKAIHELEKVKKQIEQEKSEIQAALEEAEASLEHEEG 1413
Query: 5419 ---RAQMAALEAK------------------------VQYLEDQLNVEGQEKTAANRAAR 5517
R Q+ + K V+ ++ L+ E + + A R +
Sbjct: 1414 KILRLQLELNQVKSEIDRKIAEKDEEIDQLKRNHLRIVESMQSTLDAEIRSRNEALRLKK 1473
Query: 5518 RLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEA-------EDEMSRERT 5676
++E LN+ Q R +A++ L + ++ + LD+A +++++
Sbjct: 1474 KMEGDLNEMEIQLSHANRVAAEAQKNLRNTQGVLKDTQIHLDDALRTQEDLKEQVAMVER 1533
Query: 5677 KHRNVQREADDLLDANEQLTR 5739
+ +Q E ++L A EQ R
Sbjct: 1534 RANLLQAEIEELRAALEQTER 1554
Score = 97.1 bits (240), Expect = 5e-18
Identities = 110/559 (19%), Positives = 244/559 (42%), Gaps = 27/559 (4%)
Frame = +1
Query: 3046 DHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMG 3225
D +R + +AK +L +L + E+ + + LE+ K++L E+ED +
Sbjct: 1235 DAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERANA 1294
Query: 3226 KVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNK 3405
L+ + D+ L +Y+E + QK+ R + T + +++ E +
Sbjct: 1295 ACAALDKKQKNFDKILSEWKQKYEETQTELEASQKESRSLSTELFKMKNAYEESLDHLET 1354
Query: 3406 AEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTM---EGK 3576
+ + + ++ + + + L+ + + ++E + + A+E+ + ++ EGK
Sbjct: 1355 LKRENKNLQQEISDLTEQIAEGGKAIHELEKVKKQIEQEKSEIQAALEEAEASLEHEEGK 1414
Query: 3577 I-------EEQKAKFSRQVEELHDQIEQHKKQRSQL-EKQQNQADQERADMAQEIALLQA 3732
I + K++ R++ E ++I+Q K+ ++ E Q+ D E + + L +
Sbjct: 1415 ILRLQLELNQVKSEIDRKIAEKDEEIDQLKRNHLRIVESMQSTLDAEIRSRNEALRLKKK 1474
Query: 3733 SRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFAN 3912
D+++ E L AE+ ++ R L+ ++ LD R +E+ + A
Sbjct: 1475 MEGDLNEM----EIQLSHANRVAAEAQKNLRNTQGVLKDTQIHLDDALRTQEDLKEQVAM 1530
Query: 3913 MQRR--LATAXXXXXXXXXXXXXXTRLKIAN------INRARQLEDEKNALLDEKEEAEG 4068
++RR L A +R K+A R + L + +L++ K++ E
Sbjct: 1531 VERRANLLQAEIEELRAALEQTERSR-KVAEQELMDASERVQLLHTQNTSLINTKKKLET 1589
Query: 4069 LRAHLEKEIHAARQGAGEARRKAEESVN---QQLEELRKK--NLRDVEHLQKQLEESEVA 4233
+ ++ E+ Q A A KA++++ EEL+K+ +E ++K L+++
Sbjct: 1590 DISQIQSEMEDTIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLDQT--V 1647
Query: 4234 KERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAM 4413
K+ L+ + Q L+ +++ + A R+ E + + AE V+K +
Sbjct: 1648 KDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVDSEQKRSAEAVKGVRKYERRVKEL 1707
Query: 4414 SQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAK 4593
+ + + +L L + VD ++ ++ +R ++ + S N F K HELE+A+
Sbjct: 1708 TYQSEEDRKNILRLQDLVDKLQMKVKS---YKRQAEEAEELSNVNLSKFRKIQHELEEAE 1764
Query: 4594 RS---LEAELNDMRVQMEE 4641
E+++N +RV+ E
Sbjct: 1765 ERADIAESQVNKLRVKSRE 1783
Score = 54.7 bits (130), Expect = 3e-05
Identities = 79/335 (23%), Positives = 135/335 (39%), Gaps = 38/335 (11%)
Frame = +1
Query: 4852 KIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADR 5031
KI+ + E + E+AN +KEE+ + ++ +E + +LL+E +
Sbjct: 839 KIKPLLKSAESEKEMAN-MKEEFEKTKEELAKSEAK-------RKELEEKMVSLLQEKND 890
Query: 5032 KFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXX 5211
V+AE + L +A E Q K K +LEAKI +
Sbjct: 891 LQLQVQAEADSLADAEERCDQLIKT----------------------KIQLEAKIKEVTE 928
Query: 5212 XXXXXQS-NCELAIDKQRKAQVQLEQITTDLS-MERTLNQKTEAEKQSLERSNRDYKAKI 5385
+ N EL K+RK + + ++ D+ +E TL K E EK + E ++ ++
Sbjct: 929 RAEDEEEINAELTA-KKRKLEDECSELKKDIDDLELTL-AKVEKEKHATENKVKNLTEEM 986
Query: 5386 TELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFED- 5562
L+ + + A EA Q L+D L E + +A +LE++++D T Q E
Sbjct: 987 AALDENIAKLTKEKKALQEAHQQTLDD-LQAEEDKVNTLTKAKTKLEQQVDDATLQHEAT 1045
Query: 5563 -----EKRANEQA------------KELLEK-------------SNLKN-----RNLRRQ 5637
+K A+ A K+ LEK SN+++ +L +
Sbjct: 1046 AVALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMESVSKAKASLEKT 1105
Query: 5638 LDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
ED++S +TK QR +DL +L E
Sbjct: 1106 CRALEDQLSEIKTKEEEHQRMINDLNAQRARLQTE 1140
>gi|42658064|ref|XP_376656.1| hypothetical protein FLJ22037 [Homo
sapiens]
Length = 1915
Score = 941 bits (2431), Expect = 0.0
Identities = 616/1959 (31%), Positives = 1011/1959 (51%), Gaps = 78/1959 (3%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
++ CWV D+ EGF+ G I+ E D+V V+ + T++ +T+ +DD+Q+ NPPKF + DM++
Sbjct: 37 KRSCWVKDEKEGFVAGEIQSEQGDQVTVKTI-TNQTLTVKKDDIQQMNPPKFYQASDMAD 95
Query: 256 LTYLNEASVLHNLKDRYYSSLIY------TYSGLFCVVINPYKKLPIYSEDLIEEFKGKK 417
+T+LNEASVL NL+ RY + IY TYSGLFCV +NPYK LPIY + +KGKK
Sbjct: 96 MTFLNEASVLDNLRQRYTNMRIYVSARDGTYSGLFCVTVNPYKWLPIYGARVANMYKGKK 155
Query: 418 RHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKS 597
R EMPPH+F+I+D AY ML +RE+QS+L TGESGAGKTENTKKVIQY A++ G +
Sbjct: 156 RTEMPPHLFSISDNAYHDMLMDRENQSMLITGESGAGKTENTKKVIQYFANIGGTGK--- 212
Query: 598 LNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDM 777
Q D + G LE Q++QANP+LEAFGN+KT +N+NSSRFGKFIRI+F
Sbjct: 213 ----------QTTDKK---GSLEDQVIQANPVLEAFGNAKTTRNNNSSRFGKFIRIHFGT 259
Query: 778 SGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRFLVN 957
+G ++GA+IE YLLEKSRV+ Q ERS+HIFYQIL + LL V+
Sbjct: 260 TGKLAGADIESYLLEKSRVISQQAAERSYHIFYQILSNKKPELVESLLLVPNPKEYHWVS 319
Query: 958 RGIT-LPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAM 1134
+G+T + N+DD +E T + ++GF+ +E ++ ++ ++ GN++F Q+ + +QA
Sbjct: 320 QGVTTVDNMDDKEELQITDEAFDVLGFSAEEKMAVYKLTGGIMHFGNMKFKQKPRDEQAE 379
Query: 1135 LQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYER 1314
+ V KV HL+GL ELQK RPR+KVG EFV K QN EQ + ++ A+ KA Y++
Sbjct: 380 VDTTEVADKVAHLMGLNSGELQKGITRPRVKVGNEFVQKGQNMEQCQNSIGALGKAVYDK 439
Query: 1315 LFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTM 1494
+FKWLV RINK+LD T Q FIG+LDIAGFEIF+ NSFEQ+CIN+TNEKLQQ FN+ M
Sbjct: 440 MFKWLVARINKTLD-TKMQRQFFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNHHM 498
Query: 1495 FILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQ 1674
F+LEQEEY+REGIEW FIDFGLDLQ IDL+EKPMG+ ++L+E+C+FPKA D +F L
Sbjct: 499 FVLEQEEYKREGIEWVFIDFGLDLQACIDLLEKPMGIFSILEEQCVFPKATDATFKAALY 558
Query: 1675 KTH-NKHPKFIVP-DMRSKS---HFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNS 1839
H K F+ P +SK HF +VHYAG V Y+ WL KN DPLNE VVGL Q S
Sbjct: 559 DNHLGKSSNFLKPKGGKSKGPEVHFELVHYAGTVGYNITGWLEKNKDPLNETVVGLFQKS 618
Query: 1840 TDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPH 2019
+ +A ++K+ E G+ A + H
Sbjct: 619 SVAILALLFKEEEAPGVIDAHL-----------------------------------IMH 643
Query: 2020 FVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPD 2199
+ C N VLE +R ICR+GFPNR+ + EF+ RY++L P+
Sbjct: 644 QLAC--------------NGVLEGIR---------ICRKGFPNRLQYPEFKQRYQVLNPN 680
Query: 2200 VIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQ 2379
VIP+ F+D K++ ++ A+D+D N Y+IG +KVFFR G+LA LE+ RD +L ++ Q
Sbjct: 681 VIPQGFVDNKKASELLLAAIDLDVNEYKIGHTKVFFRAGILARLEDMRDERLAKIMTMLQ 740
Query: 2380 AQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKP--LLQVTRTDD 2553
+ RGFL R + + L+ W R K P + T D
Sbjct: 741 CRLRGFLMRVEFKKMLERRISNEFLFPSA---GHLQPWTEGRDTRKPGPNTFIVTHSTLD 797
Query: 2554 EIRAKDDELRATKERLLK-MEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRG 2730
R L+ ++ + K ++ F K ++V + +QE E A+ +++R
Sbjct: 798 SFRRMG--LKVIQQNVHKFLQLRFWGWWKLYNKV----KPLLNVARQEEEMKAKEEELR- 850
Query: 2731 RLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXX 2910
+ + QEL V ++ ++ + + + E + D
Sbjct: 851 KAMAQTQELVNKVKELEEKTATLSQEKNDLTIQLQAEQENLMDAEERLTWMMKTKMDLES 910
Query: 2911 DKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGR 3090
+++ + A GL T L E K K
Sbjct: 911 QISDMRERLEEEEGMAASLSAAKRKLEGELSDLKRDLEGLETTLAKTE-------KEKQA 963
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L++++ L DL+ ++L++ KR L EEL+ + + ++
Sbjct: 964 LDHKVRTLTGDLSLREDSITKLQKEKRAL------------------EELHQKTL---DD 1002
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
LQ E V + K + T I EL ++ E E+ R + E RR+ + L K+
Sbjct: 1003 LQ-------AEEDKVNHLTKNNSKLSTQIHELEDNWEQEKKIRAEVEKARRKAESDL-KM 1054
Query: 3451 KGDVLDKVDEATM-LQDLMSRKDEEVNATKRAIE---QIQHTMEGKIEEQKAKFSRQVEE 3618
D L++++ + + L++++ ++D E+N+ E + T++ K++E + + EE
Sbjct: 1055 TIDNLNEMERSKLDLEEVVKKRDLEINSVNSKYEDEQSLNSTLQRKLKEHQDRIEELEEE 1114
Query: 3619 LHDQ------IEQHKKQRSQLEKQQNQADQ------------------ERADMAQEIALL 3726
L + IEQ++K+ ++L K + + ++ A++ + + L
Sbjct: 1115 LEAERAMRAKIEQNRKREAELLKLRRELEEAALQSEATASTLRKKHVDSMAELTEHVESL 1174
Query: 3727 QASRADIDKKRKIHEAHLMEIQANL-------AESDEHKRTLIDQLERSRDELDHLNRVR 3885
Q ++ ++K +++ +A + ++ A++ ++ H R L D L + ++ L R +
Sbjct: 1175 QRVKSKLEKDKQVMKAEIDDLNASMETIQKSKMNAEAHVRKLEDSLSEANAKVAELERNQ 1234
Query: 3886 EEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRA----RQLEDEKNA----- 4038
E +Q + R+K + ++ RQL++E +
Sbjct: 1235 AEINAIRTRLQAENSELSREYEESQSRLNQILRIKTSLTSQVDDYKRQLDEESKSRSTAV 1294
Query: 4039 ------------LLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN 4182
+ ++ EE +G ++ L++ + R K E Q+ EEL +
Sbjct: 1295 VSLANTKHDLDLVKEQLEEEQGGKSELQRLVSKLNTEVTTWRTKYETDAIQRTEELEETK 1354
Query: 4183 LRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFE 4353
+ LQ+ E +E A+ R + ++K+++Q E+ED +++LE A+ +K+Q+ F+
Sbjct: 1355 RKLAARLQEAEEAAETAQARAASLEKNKQRLQAEVEDLTIDLEKANAAAAALDKKQRLFD 1414
Query: 4354 SQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQ 4533
+AE + ++ ++ D+ +E R T + + EHLE + ++LQ+E++
Sbjct: 1415 KMLAEWQQKCEELQVEVDSSQKECRMYMTESFKIKTAYEESLEHLESVKKENKTLQEEIK 1474
Query: 4534 DSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKS 4713
D I + G++VHEL+K K+ LE E +++V +EE E +L++ E +R+++ +K+
Sbjct: 1475 DLIDQLGEGGRSVHELQKLKKKLEMEKEELQVALEEAESSLEVEESKVIRIQLELAQVKA 1534
Query: 4714 ESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLE 4893
+ DR I K+ E E R+ + I L+ LE E +G++ A+ +KK+E + E+E QL+
Sbjct: 1535 DIDRRIHEKEEEFEATRKNHQRAIESLQASLEAEAKGRAEALRLKKKMETDLNEMEIQLD 1594
Query: 4894 VANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLRE 5073
AN+ E + Q++ +E + E++ +R+ ++ E E++R
Sbjct: 1595 HANKNNSELVKTLKRLQQQIKDLQVQMDEDARQHEELRKQYNLQERRLSLLQTELEEVRS 1654
Query: 5074 ANEGLMQARKQXXXXXXXXXXXRAKGGGISSEE----KRRLEAKIAQXXXXXXXXQSNCE 5241
A EG ++RK + I ++ KR+LE+ + + S
Sbjct: 1655 ALEGSERSRKLLEQEVVEITEWHNE-INIQNQSLLVVKRKLESDVQRISNEHEELISEFR 1713
Query: 5242 LAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRAR 5421
L ++ +KA + ++ +L E+ E K++ E + +D +AK+ E E A +
Sbjct: 1714 LTEERAKKAMMDAARMAEELRQEQDHCMHLEKIKKNYEVTIKDLQAKMEEAEQLALKGGK 1773
Query: 5422 AQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLE 5601
+ LEA+++ LE +L+ E ++ + + E+RL + Q E++ + N++ + L+E
Sbjct: 1774 RTIMKLEARIKELETELDGEQKQHVETVKTLCKNERRLKELVFQTEEDHKTNQRMQALVE 1833
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLD 5718
K K + +RQ++EAED+ ++ ++R E DD D
Sbjct: 1834 KLQNKLKVYKRQIEEAEDQANQTLARYRKTVHELDDAED 1872
Score = 159 bits (402), Expect = 8e-37
Identities = 185/914 (20%), Positives = 400/914 (43%), Gaps = 27/914 (2%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDE 3267
+L N++ L +E + K++ E+ RK +A+ ++ L K+ ++EE L +
Sbjct: 824 KLYNKVKPLLNVARQEEEMKAK-EEELRKAMAQTQE----LVNKVKELEEKTATLSQEKN 878
Query: 3268 ELQHQLTRYDEE----SANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVA 3435
+L QL E +T M K D+++ I ++RE +E E +R++
Sbjct: 879 DLTIQLQAEQENLMDAEERLTWMMKTKMDLESQISDMRERLEEEEGMAASLSAAKRKLEG 938
Query: 3436 QLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQK------AK 3597
+L +K D+ L+ +++ ++E K+A++ T+ G + ++ K
Sbjct: 939 ELSDLKRDLEG-------LETTLAKTEKE----KQALDHKVRTLTGDLSLREDSITKLQK 987
Query: 3598 FSRQVEELH----DQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKI 3765
R +EELH D ++ + + + L K ++ + ++ + RA+++K R+
Sbjct: 988 EKRALEELHQKTLDDLQAEEDKVNHLTKNNSKLSTQIHELEDNWEQEKKIRAEVEKARRK 1047
Query: 3766 HEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
E+ L NL E + K L + +++ E++ +N E+E+ + +QR+L
Sbjct: 1048 AESDLKMTIDNLNEMERSKLDLEEVVKKRDLEINSVNSKYEDEQSLNSTLQRKLKE---- 1103
Query: 3946 XXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEA 4125
+ +R +LE+E A + + E R E E+ R+ EA
Sbjct: 1104 -----------------HQDRIEELEEELEAERAMRAKIEQNRKR-EAELLKLRRELEEA 1145
Query: 4126 RRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELEN 4305
++E + + LRKK++ + L + +E + K ++ + K+ ++ E++D + +E
Sbjct: 1146 ALQSEATAST----LRKKHVDSMAELTEHVESLQRVKSKLEKDKQVMKAEIDDLNASMET 1201
Query: 4306 VRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEH 4485
++ S ++E +K E ++E V A L+R+ E+ TR+ + +E+ +E+
Sbjct: 1202 IQKSKMNAEAHVRKLEDSLSEANAKV--AELERN--QAEINAIRTRLQAENSELS--REY 1255
Query: 4486 LEESDRVRRSLQQELQDSISNK-DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQI 4662
E R+ + L+ ++ S++++ DD+ + + E K++ + L + + ++ +++ L+
Sbjct: 1256 EESQSRLNQILR--IKTSLTSQVDDYKRQLDEESKSRSTAVVSLANTKHDLDLVKEQLEE 1313
Query: 4663 AED---------ARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENE 4815
+ ++L EVT K E+D AI + E EE +R L ++++ E E
Sbjct: 1314 EQGGKSELQRLVSKLNTEVTTWRTKYETD-AIQRTE-ELEETKRKLAARLQEAEEAAETA 1371
Query: 4816 KRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAK 4995
+ + ++++++ ++ +L LE AN E+Q +CEE +
Sbjct: 1372 QARAASLEKNKQRLQAEVEDLTIDLEKANAAAAALDKKQRLFDKMLAEWQQKCEELQVEV 1431
Query: 4996 EDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEE- 5172
+ R + ++ E+ E E + + K +GG E
Sbjct: 1432 DSSQKECRMYMTESFKIKTAYEESLEHLESVKKENKTLQEEIKDLIDQLGEGGRSVHELQ 1491
Query: 5173 --KRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQ 5346
K++LE + + +S+ E+ K + Q++L Q+ D+ +R +++K E
Sbjct: 1492 KLKKKLEMEKEELQVALEEAESSLEVEESKVIRIQLELAQVKADI--DRRIHEKEE---- 1545
Query: 5347 SLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLE 5526
E E+ ++ RA ++ L+ L E + + A R +++E
Sbjct: 1546 --------------EFEATRKNHQRA--------IESLQASLEAEAKGRAEALRLKKKME 1583
Query: 5527 KRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREAD 5706
LN+ Q + + N + + L++ + ++L+ Q+DE + E K N+Q
Sbjct: 1584 TDLNEMEIQLDHANKNNSELVKTLKRLQQQIKDLQVQMDE-DARQHEELRKQYNLQERRL 1642
Query: 5707 DLLDANEQLTRELM 5748
LL + R +
Sbjct: 1643 SLLQTELEEVRSAL 1656
>gi|42658517|ref|XP_379895.1| similar to superfast myosin heavy chain
[Homo sapiens]
Length = 1915
Score = 939 bits (2426), Expect = 0.0
Identities = 615/1959 (31%), Positives = 1010/1959 (51%), Gaps = 78/1959 (3%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
++ CWV D+ EGF+ G I+ E D+V V+ + T++ +T+ +DD+Q+ NPPKF + DM++
Sbjct: 37 KRSCWVKDEKEGFVAGEIQSEQGDQVTVKTI-TNQTLTVKKDDIQQMNPPKFYQASDMAD 95
Query: 256 LTYLNEASVLHNLKDRYYSSLIY------TYSGLFCVVINPYKKLPIYSEDLIEEFKGKK 417
+T+LNEASVL NL+ RY + IY TYSGLFCV +NPYK LPIY + +KGKK
Sbjct: 96 MTFLNEASVLDNLRQRYTNMRIYVSARDGTYSGLFCVTVNPYKWLPIYGARVANMYKGKK 155
Query: 418 RHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKS 597
R EMPPH+F+I+D AY ML +RE+QS+L TGESGAGKTENTKKVIQY A++ G +
Sbjct: 156 RTEMPPHLFSISDNAYHDMLMDRENQSMLITGESGAGKTENTKKVIQYFANIGGTGK--- 212
Query: 598 LNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDM 777
Q D + G LE Q++QANP+LEAFGN+KT +N+NSSRFGKFIRI+F
Sbjct: 213 ----------QTTDKK---GSLEDQVIQANPVLEAFGNAKTTRNNNSSRFGKFIRIHFGT 259
Query: 778 SGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRFLVN 957
+G ++GA+ E YLLEKSRV+ Q ERS+HIFYQIL + LL V+
Sbjct: 260 TGKLAGADTESYLLEKSRVISQQAAERSYHIFYQILSNKKPELVESLLLVPNPKEYHWVS 319
Query: 958 RGIT-LPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAM 1134
+G+T + N+DD +E T + ++GF+ +E ++ ++ ++ GN++F Q+ + +QA
Sbjct: 320 QGVTTVDNMDDKEELQITDEAFDVLGFSAEEKMAVYKLTGGIMHFGNMKFKQKPRDEQAE 379
Query: 1135 LQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYER 1314
+ V KV HL+GL ELQK RPR+KVG EFV K QN EQ + ++ A+ KA Y++
Sbjct: 380 VDTTEVADKVAHLMGLNSGELQKGITRPRVKVGNEFVQKGQNMEQCQNSIGALGKAVYDK 439
Query: 1315 LFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTM 1494
+FKWLV RINK+LD T Q FIG+LDIAGFEIF+ NSFEQ+CIN+TNEKLQQ FN+ M
Sbjct: 440 MFKWLVARINKTLD-TKMQRQFFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNHHM 498
Query: 1495 FILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQ 1674
F+LEQEEY+REGIEW FIDFGLDLQ IDL+EKPMG+ ++L+E+C+FPKA D +F L
Sbjct: 499 FVLEQEEYKREGIEWVFIDFGLDLQACIDLLEKPMGIFSILEEQCVFPKATDATFKAALY 558
Query: 1675 KTH-NKHPKFIVP-DMRSKS---HFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNS 1839
H K F+ P +SK HF +VHYAG V Y+ WL KN DPLNE VVGL Q S
Sbjct: 559 DNHLGKSSNFLKPKGGKSKGPEVHFELVHYAGTVGYNITGWLEKNKDPLNETVVGLFQKS 618
Query: 1840 TDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPH 2019
+ +A ++K+ E G+ A + H
Sbjct: 619 SVAILALLFKEEEAPGVIDAHL-----------------------------------IMH 643
Query: 2020 FVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPD 2199
+ C N VLE +R ICR+GFPNR+ + EF+ RY++L P+
Sbjct: 644 QLAC--------------NGVLEGIR---------ICRKGFPNRLQYPEFKQRYQVLNPN 680
Query: 2200 VIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQ 2379
VIP+ F+D K++ ++ A+D+D N Y+IG +KVFFR G+LA LE+ RD +L ++ Q
Sbjct: 681 VIPQGFVDNKKASELLLAAIDLDVNEYKIGHTKVFFRAGILARLEDMRDERLAKIMTMLQ 740
Query: 2380 AQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKP--LLQVTRTDD 2553
+ RGFL R + + L+ W R K P + T D
Sbjct: 741 CRLRGFLMRVEFKKMLERRISNEFLFPSA---GHLQPWTEGRDTRKPGPNTFIVTHSTLD 797
Query: 2554 EIRAKDDELRATKERLLK-MEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRG 2730
R L+ ++ + K ++ F K ++V + +QE E A+ +++R
Sbjct: 798 SFRRMG--LKVIQQNVHKFLQLRFWGWWKLYNKV----KPLLNVARQEEEMKAKEEELR- 850
Query: 2731 RLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXX 2910
+ + QEL V ++ ++ + + + E + D
Sbjct: 851 KAMAQTQELVNKVKELEEKTATLSQEKNDLTIQLQAEQENLMDAEERLTWMMKTKMDLES 910
Query: 2911 DKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGR 3090
+++ + A GL T L E K K
Sbjct: 911 QISDMRERLEEEEGMAASLSAAKRKLEGELSDLKRDLEGLETTLAKTE-------KEKQA 963
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L++++ L DL+ ++L++ KR L EEL+ + + ++
Sbjct: 964 LDHKVRTLTGDLSLREDSITKLQKEKRAL------------------EELHQKTL---DD 1002
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
LQ E V + K + T I EL ++ E E+ R + E RR+ + L K+
Sbjct: 1003 LQ-------AEEDKVNHLTKNNSKLSTQIHELEDNWEQEKKIRAEVEKARRKAESDL-KM 1054
Query: 3451 KGDVLDKVDEATM-LQDLMSRKDEEVNATKRAIE---QIQHTMEGKIEEQKAKFSRQVEE 3618
D L++++ + + L++++ ++D E+N+ E + T++ K++E + + EE
Sbjct: 1055 TIDNLNEMERSKLDLEEVVKKRDLEINSVNSKYEDEQSLNSTLQRKLKEHQDRIEELEEE 1114
Query: 3619 LHDQ------IEQHKKQRSQLEKQQNQADQ------------------ERADMAQEIALL 3726
L + IEQ++K+ ++L K + + ++ A++ + + L
Sbjct: 1115 LEAERAMRAKIEQNRKREAELLKLRRELEEAALQSEATASTLRKKHVDSMAELTEHVESL 1174
Query: 3727 QASRADIDKKRKIHEAHLMEIQANL-------AESDEHKRTLIDQLERSRDELDHLNRVR 3885
Q ++ ++K +++ +A + ++ A++ ++ H R L D L + ++ L R +
Sbjct: 1175 QRVKSKLEKDKQVMKAEIDDLNASMETIQKSKMNAEAHVRKLEDSLSEANAKVAELERNQ 1234
Query: 3886 EEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRA----RQLEDEKNA----- 4038
E +Q + R+K + ++ RQL++E +
Sbjct: 1235 AEINAIRTRLQAENSELSREYEESQSRLNQILRIKTSLTSQVDDYKRQLDEESKSRSTAV 1294
Query: 4039 ------------LLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKN 4182
+ ++ EE +G ++ L++ + R K E Q+ EEL +
Sbjct: 1295 VSLANTKHDLDLVKEQLEEEQGGKSELQRLVSKLNTEVTTWRTKYETDAIQRTEELEETK 1354
Query: 4183 LRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFE 4353
+ LQ+ E +E A+ R + ++K+++Q E+ED +++LE A+ +K+Q+ F+
Sbjct: 1355 RKLAARLQEAEEAAETAQARAASLEKNKQRLQAEVEDLTIDLEKANAAAAALDKKQRLFD 1414
Query: 4354 SQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQ 4533
+AE + ++ ++ D+ +E R T + + EHLE + ++LQ+E++
Sbjct: 1415 KMLAEWQQKCEELQVEVDSSQKECRMYMTESFKIKTAYEESLEHLESVKKENKTLQEEIK 1474
Query: 4534 DSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKS 4713
D I + G++VHEL+K K+ LE E +++V +EE E +L++ E +R+++ +K+
Sbjct: 1475 DLIDQLGEGGRSVHELQKLKKKLEMEKEELQVALEEAESSLEVEESKVIRIQLELAQVKA 1534
Query: 4714 ESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLE 4893
+ DR I K+ E E R+ + I L+ LE E +G++ A+ +KK+E + E+E QL+
Sbjct: 1535 DIDRRIHEKEEEFEATRKNHQRAIESLQASLEAEAKGRAEALRLKKKMETDLNEMEIQLD 1594
Query: 4894 VANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLRE 5073
AN+ E + Q++ +E + E++ +R+ ++ E E++R
Sbjct: 1595 HANKNNSELVKTLKRLQQQIKDLQVQMDEDARQHEELRKQYNLQERRLSLLQTELEEVRS 1654
Query: 5074 ANEGLMQARKQXXXXXXXXXXXRAKGGGISSEE----KRRLEAKIAQXXXXXXXXQSNCE 5241
A EG ++RK + I ++ KR+LE+ + + S
Sbjct: 1655 ALEGSERSRKLLEQEVVEITEWHNE-INIQNQSLLVVKRKLESDVQRISNEHEELISEFR 1713
Query: 5242 LAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRAR 5421
L ++ +KA + ++ +L E+ E K++ E + +D +AK+ E E A +
Sbjct: 1714 LTEERAKKAMMDAARMAEELRQEQDHCMHLEKIKKNYEVTIKDLQAKMEEAEQLALKGGK 1773
Query: 5422 AQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLE 5601
+ LEA+++ LE +L+ E ++ + + E+RL + Q E++ + N++ + L+E
Sbjct: 1774 RTIMKLEARIKELETELDGEQKQHVETVKTLCKNERRLKELVFQTEEDHKTNQRMQALVE 1833
Query: 5602 KSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLD 5718
K K + +RQ++EAED+ ++ ++R E DD D
Sbjct: 1834 KLQNKLKVYKRQIEEAEDQANQTLARYRKTVHELDDAED 1872
Score = 159 bits (402), Expect = 8e-37
Identities = 185/914 (20%), Positives = 400/914 (43%), Gaps = 27/914 (2%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDE 3267
+L N++ L +E + K++ E+ RK +A+ ++ L K+ ++EE L +
Sbjct: 824 KLYNKVKPLLNVARQEEEMKAK-EEELRKAMAQTQE----LVNKVKELEEKTATLSQEKN 878
Query: 3268 ELQHQLTRYDEE----SANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVA 3435
+L QL E +T M K D+++ I ++RE +E E +R++
Sbjct: 879 DLTIQLQAEQENLMDAEERLTWMMKTKMDLESQISDMRERLEEEEGMAASLSAAKRKLEG 938
Query: 3436 QLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQK------AK 3597
+L +K D+ L+ +++ ++E K+A++ T+ G + ++ K
Sbjct: 939 ELSDLKRDLEG-------LETTLAKTEKE----KQALDHKVRTLTGDLSLREDSITKLQK 987
Query: 3598 FSRQVEELH----DQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKI 3765
R +EELH D ++ + + + L K ++ + ++ + RA+++K R+
Sbjct: 988 EKRALEELHQKTLDDLQAEEDKVNHLTKNNSKLSTQIHELEDNWEQEKKIRAEVEKARRK 1047
Query: 3766 HEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
E+ L NL E + K L + +++ E++ +N E+E+ + +QR+L
Sbjct: 1048 AESDLKMTIDNLNEMERSKLDLEEVVKKRDLEINSVNSKYEDEQSLNSTLQRKLKE---- 1103
Query: 3946 XXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEA 4125
+ +R +LE+E A + + E R E E+ R+ EA
Sbjct: 1104 -----------------HQDRIEELEEELEAERAMRAKIEQNRKR-EAELLKLRRELEEA 1145
Query: 4126 RRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELEN 4305
++E + + LRKK++ + L + +E + K ++ + K+ ++ E++D + +E
Sbjct: 1146 ALQSEATAST----LRKKHVDSMAELTEHVESLQRVKSKLEKDKQVMKAEIDDLNASMET 1201
Query: 4306 VRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEH 4485
++ S ++E +K E ++E V A L+R+ E+ TR+ + +E+ +E+
Sbjct: 1202 IQKSKMNAEAHVRKLEDSLSEANAKV--AELERN--QAEINAIRTRLQAENSELS--REY 1255
Query: 4486 LEESDRVRRSLQQELQDSISNK-DDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQI 4662
E R+ + L+ ++ S++++ DD+ + + E K++ + L + + ++ +++ L+
Sbjct: 1256 EESQSRLNQILR--IKTSLTSQVDDYKRQLDEESKSRSTAVVSLANTKHDLDLVKEQLEE 1313
Query: 4663 AED---------ARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENE 4815
+ ++L EVT K E+D AI + E EE +R L ++++ E E
Sbjct: 1314 EQGGKSELQRLVSKLNTEVTTWRTKYETD-AIQRTE-ELEETKRKLAARLQEAEEAAETA 1371
Query: 4816 KRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAK 4995
+ + ++++++ ++ +L LE AN E+Q +CEE +
Sbjct: 1372 QARAASLEKNKQRLQAEVEDLTIDLEKANAAAAALDKKQRLFDKMLAEWQQKCEELQVEV 1431
Query: 4996 EDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEE- 5172
+ R + ++ E+ E E + + K +GG E
Sbjct: 1432 DSSQKECRMYMTESFKIKTAYEESLEHLESVKKENKTLQEEIKDLIDQLGEGGRSVHELQ 1491
Query: 5173 --KRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQ 5346
K++LE + + +S+ E+ K + Q++L Q+ D+ +R +++K E
Sbjct: 1492 KLKKKLEMEKEELQVALEEAESSLEVEESKVIRIQLELAQVKADI--DRRIHEKEE---- 1545
Query: 5347 SLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLE 5526
E E+ ++ RA ++ L+ L E + + A R +++E
Sbjct: 1546 --------------EFEATRKNHQRA--------IESLQASLEAEAKGRAEALRLKKKME 1583
Query: 5527 KRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREAD 5706
LN+ Q + + N + + L++ + ++L+ Q+DE + E K N+Q
Sbjct: 1584 TDLNEMEIQLDHANKNNSELVKTLKRLQQQIKDLQVQMDE-DARQHEELRKQYNLQERRL 1642
Query: 5707 DLLDANEQLTRELM 5748
LL + R +
Sbjct: 1643 SLLQTELEEVRSAL 1656
>gi|2119296|pir||I64833 smooth muscle myosin heavy chain isoform SM1B
- rat (fragment)
gi|385469|gb|AAB26776.1| smooth muscle myosin heavy chain isoform
SM1B; SMHC SM1B [Rattus sp.]
Length = 706
Score = 936 bits (2420), Expect = 0.0
Identities = 465/713 (65%), Positives = 572/713 (80%), Gaps = 8/713 (1%)
Frame = +1
Query: 412 KKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRN 591
KKRHEMPPHI+AIADTAYRSMLQ+REDQSILCTGESGAGKTENTKKVIQYLA VA + +
Sbjct: 1 KKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKG 60
Query: 592 KSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINF 771
+ + A +++ + GELE QLLQANPILEAFGN+KTVKNDNSSRFGKFIRINF
Sbjct: 61 QGPSFAYKKD-------SSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINF 113
Query: 772 DMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRFL 951
D++GYI GANIE YLLEKSR +R A+DER+FHIFY ++ G K +++ LLE ++Y FL
Sbjct: 114 DVTGYIVGANIETYLLEKSRAIRHARDERTFHIFYYLIAGAKEKMRNDLLLESFNSYTFL 173
Query: 952 VNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQA 1131
N + +P D + F T+ +M IMGF+++E +I++VVS+VL LGN+ F +E+ +DQA
Sbjct: 174 SNGFVPIPAAQDDEMFQETLEAMSIMGFSEEEQLAILKVVSSVLQLGNIVFKKERNTDQA 233
Query: 1132 MLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYE 1311
+ D+ QKVCHL+G+ V + +A L PRIKVGR+ V KAQ +EQA+FA+EA+AKA+YE
Sbjct: 234 SMPDNTAAQKVCHLVGINVTDFTRAILTPRIKVGRDVVQKAQTKEQADFAIEALAKATYE 293
Query: 1312 RLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNT 1491
RLF+W+++R+NK+LD+THRQGASF+GILDIAGFEIF++NSFEQ+CINYTNEKLQQLFN+T
Sbjct: 294 RLFRWILSRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHT 353
Query: 1492 MFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEK---PMGVLALLDEECLFPKANDKSFV 1662
MFILEQEEYQREGIEW+FIDFGLDLQP I+LIE+ P GVLALLDEEC FPKA DKSFV
Sbjct: 354 MFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFV 413
Query: 1663 EKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNS 1839
EKL HPKF P ++ K+ F+++HYAG+VDY+A WL KNMDPLN+NV L+ S
Sbjct: 414 EKLCSEQGNHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNAS 473
Query: 1840 TDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQLHKEQLTKLMTTLRN 2007
+D FVA +WKD + G+ A+M E++ +++KGMFRTV QL+KEQL KLMTTLRN
Sbjct: 474 SDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRN 533
Query: 2008 TSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEI 2187
T+P+FVRCIIPNHEK+SGK+++ LVLEQLRCNGVLEGIRICRQGFPNR+ FQEFR RYEI
Sbjct: 534 TTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEI 593
Query: 2188 LTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALI 2367
L + IPK F+DGK++ MI AL++D NLYRIGQSK+FFRTGVLAHLEEERDLK+T +I
Sbjct: 594 LAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVI 653
Query: 2368 MNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKP 2526
M FQA CRG+L+R+ +T N AYLKLRNWQWWRLFTKVKP
Sbjct: 654 MAFQAMCRGYLARKAFTKRQQQLTASKVIQRNCAAYLKLRNWQWWRLFTKVKP 706
>gi|2119289|pir||I51893 smooth muscle myosin heavy chain isoform SM1A
- rat (fragment)
gi|385467|gb|AAB26775.1| smooth muscle myosin heavy chain isoform
SM1A; SMHC SM1A [Rattus sp.]
gi|447591|prf||1915177A myosin:SUBUNIT=H
Length = 699
Score = 935 bits (2417), Expect = 0.0
Identities = 465/713 (65%), Positives = 568/713 (79%), Gaps = 8/713 (1%)
Frame = +1
Query: 412 KKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRN 591
KKRHEMPPHI+AIADTAYRSMLQ+REDQSILCTGESGAGKTENTKKVIQYLA VA + +
Sbjct: 1 KKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKG 60
Query: 592 KSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINF 771
K ++ GELE QLLQANPILEAFGN+KTVKNDNSSRFGKFIRINF
Sbjct: 61 KKDSSIT--------------GELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINF 106
Query: 772 DMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRFL 951
D++GYI GANIE YLLEKSR +R A+DER+FHIFY ++ G K +++ LLE ++Y FL
Sbjct: 107 DVTGYIVGANIETYLLEKSRAIRHARDERTFHIFYYLIAGAKEKMRNDLLLESFNSYTFL 166
Query: 952 VNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQA 1131
N + +P D + F T+ +M IMGF+++E +I++VVS+VL LGN+ F +E+ +DQA
Sbjct: 167 SNGFVPIPAAQDDEMFQETLEAMSIMGFSEEEQLAILKVVSSVLQLGNIVFKKERNTDQA 226
Query: 1132 MLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYE 1311
+ D+ QKVCHL+G+ V + +A L PRIKVGR+ V KAQ +EQA+FA+EA+AKA+YE
Sbjct: 227 SMPDNTAAQKVCHLVGINVTDFTRAILTPRIKVGRDVVQKAQTKEQADFAIEALAKATYE 286
Query: 1312 RLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNT 1491
RLF+W+++R+NK+LD+THRQGASF+GILDIAGFEIF++NSFEQ+CINYTNEKLQQLFN+T
Sbjct: 287 RLFRWILSRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHT 346
Query: 1492 MFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEK---PMGVLALLDEECLFPKANDKSFV 1662
MFILEQEEYQREGIEW+FIDFGLDLQP I+LIE+ P GVLALLDEEC FPKA DKSFV
Sbjct: 347 MFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFV 406
Query: 1663 EKLQKTHNKHPKFIVP-DMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNS 1839
EKL HPKF P ++ K+ F+++HYAG+VDY+A WL KNMDPLN+NV L+ S
Sbjct: 407 EKLCSEQGNHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNAS 466
Query: 1840 TDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKGMFRTVSQLHKEQLTKLMTTLRN 2007
+D FVA +WKD + G+ A+M E++ +++KGMFRTV QL+KEQL KLMTTLRN
Sbjct: 467 SDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRN 526
Query: 2008 TSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEI 2187
T+P+FVRCIIPNHEK+SGK+++ LVLEQLRCNGVLEGIRICRQGFPNR+ FQEFR RYEI
Sbjct: 527 TTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEI 586
Query: 2188 LTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALI 2367
L + IPK F+DGK++ MI AL++D NLYRIGQSK+FFRTGVLAHLEEERDLK+T +I
Sbjct: 587 LAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVI 646
Query: 2368 MNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKP 2526
M FQA CRG+L+R+ +T N AYLKLRNWQWWRLFTKVKP
Sbjct: 647 MAFQAMCRGYLARKAFTKRQQQLTASKVIQRNCAAYLKLRNWQWWRLFTKVKP 699
>gi|13272546|gb|AAK17202.1| major plasmodial myosin heavy chain
[Physarum polycephalum]
Length = 2148
Score = 931 bits (2407), Expect = 0.0
Identities = 611/1986 (30%), Positives = 1006/1986 (49%), Gaps = 107/1986 (5%)
Frame = +1
Query: 70 AQRKLCWV---PDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKI 240
+ +K W P + F + +E DE +V + + +T+ D + NP KFD +
Sbjct: 26 SDKKFAWFNPDPKDRDTFASAEVLKEGKDEWVVR-TEEGQTLTVKMDFISPRNPAKFDGV 84
Query: 241 EDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKR 420
EDMSEL YLNEA VLHNL+ RY +IYTYSGLF V INPYK+ PIYS+ +I+ +KG++R
Sbjct: 85 EDMSELGYLNEAGVLHNLRLRYNKDVIYTYSGLFLVAINPYKRFPIYSDTIIDIYKGRRR 144
Query: 421 HEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSL 600
+E+ PHIFAIAD AYRSML ++ +QSIL TGESGAGKTENTKKVIQYL VAG N
Sbjct: 145 NEVAPHIFAIADVAYRSMLGDKLNQSILITGESGAGKTENTKKVIQYLTSVAGRVSNDPN 204
Query: 601 NAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMS 780
+ LE Q+LQANPILE+FGN+KT +N+NSSRFGKFI + F+ +
Sbjct: 205 QVS-----------------LEAQILQANPILESFGNAKTTRNNNSSRFGKFIEVQFNSA 247
Query: 781 GYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRFLVNR 960
GYISGA I+ YLLEKSRV+ QA+ ER+FHIFYQ+L G + +E+ L D Y +L
Sbjct: 248 GYISGAKIQSYLLEKSRVVFQAERERTFHIFYQLLAGATPEERKSMFLGPPDTYHYLNQS 307
Query: 961 G-ITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAML 1137
G +P ++D +F T N+ +IM ++E +I RV++ +L LGN+ FTQ D +++
Sbjct: 308 GCFDVPGINDANDFQDTKNACKIMNITEEEQEAIFRVIAGILHLGNVNFTQ-SYGDASVI 366
Query: 1138 QDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERL 1317
QD + L + +L+K + PRI+ G+E V+ +A+ +A+ KA Y RL
Sbjct: 367 QDKTSLNYAPSLFNITASQLEKGLIEPRIQTGKELVSTQLTPAKAKSGRDALTKAIYHRL 426
Query: 1318 FKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMF 1497
F W+V +IN L + +R SFIG+LDIAGFEIF NSFEQ+CIN+TNEKLQQ FN+ MF
Sbjct: 427 FLWIVKKINLVLSQQNR--VSFIGVLDIAGFEIFKNNSFEQLCINFTNEKLQQFFNHHMF 484
Query: 1498 ILEQEEYQREGIEWDFIDFGLDLQPTIDLIEK--PMGVLALLDEECLFPKANDKSFVEKL 1671
LEQEEY++E I+W FIDFG+D Q TI+LIE P G+LALLDE+ +FP A D++ + KL
Sbjct: 485 TLEQEEYKKERIDWTFIDFGMDSQATIELIESKTPPGILALLDEQSVFPNATDQTLITKL 544
Query: 1672 QKTH------------NKHPKFIVPDMRSKS-HFAVVHYAGRVDYSADQWLMKNMDPLNE 1812
TH KHPK+ P KS +F + HYAG V Y WL KN DPL
Sbjct: 545 H-THFGGGQGAQGGKAKKHPKYEEPRFADKSPNFGIYHYAGTVSYDVTNWLEKNKDPLQP 603
Query: 1813 NVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKG----MFRTVSQLHKEQL 1980
++ M++S D FV ++ + + E T+ RKG F TV+ +K QL
Sbjct: 604 DLEATMRDSKDSFVRRLFTE-------SFEDLPTSLAEYQRKGTRGAAFVTVAAQYKSQL 656
Query: 1981 TKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPF 2160
+ LM+TL+ T PHFVRCI+PNH++K G + VL+QLRCNGVLEGIRI R GFPNR +
Sbjct: 657 SNLMSTLQATHPHFVRCILPNHQQKPGYLEDACVLDQLRCNGVLEGIRITRLGFPNRTIY 716
Query: 2161 QEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEE 2340
EF RY +L PDV P+N D K + ++ L I + YR G +KVFFR G LA++EE
Sbjct: 717 SEFVKRYYLLVPDV-PRNPQDPKPATATILKGLKIPESEYRFGLTKVFFRAGQLAYIEEI 775
Query: 2341 RDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKV 2520
R+ ++ ++ QA RG++ R+ + N AYL+ +NW WW+LF K
Sbjct: 776 RERRIGEIVKVVQAAARGWVERKHFRQAREKSVSARIIQDNIRAYLEFKNWAWWKLFAKA 835
Query: 2521 KPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESE 2700
+PLL D E++ +D +++ +L + E E++L + + A +Q+ L+ E
Sbjct: 836 RPLLVGRNMDKELKERDSQIKDLSSQLAAEKAARAELERQLKEAEHKIAQLQDSLKAEKA 895
Query: 2701 NSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXX 2880
N L D L+ E + ++ LS R++ V++
Sbjct: 896 NVVNLQDANADLKQEIATHERKIANLESELSEQTKLLDSITVARKEAETKVKELTTALQD 955
Query: 2881 XXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEER 3060
K VD + L+ Q D +
Sbjct: 956 ERDARLNLEKAKRKVDDELDEVKKQHDFDVERIANLEKLKNELQAEVEELSDQFADETKS 1015
Query: 3061 AKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEEL 3240
K K ++++ L +LE N E ++EL + K +L ++L + L ++ + L
Sbjct: 1016 RASLEKQKRKIDSDLEDLENKYNEEVTQRTELSKLKNQLDSDLRSTTSQLESEIERRGIL 1075
Query: 3241 NNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTR 3420
K + L + + +EE N ++K + ++ +L ++++ E+ R+ AE R
Sbjct: 1076 EGLQKKLEAALASETAKLEEEQKNRNALEKAKKALEQQQRDLTQELQDEKKNRDTAEKAR 1135
Query: 3421 REVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKF 3600
+++ L +++ + K + L DL + ++E+ +R +E+++ + +E+ K
Sbjct: 1136 KKLDLDLTELRDQLDVKGGDVKALADLKQKVEQELEDLRRQVEELKKAV-SNLEKIKRTL 1194
Query: 3601 SRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHL 3780
Q+ + ++ + + + + L K + + +++ + Q++A Q +A +DK +K + +
Sbjct: 1195 EAQLNDANNALAESNAENANLTKLKKKLEEDLVALNQKLAEEQRDKAALDKAKKKADQDV 1254
Query: 3781 MEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXX 3960
E+++NL + TL L+ + ++L++ E+E+ +++
Sbjct: 1255 KELKSNLENVSASRATLDQNLKATEEKLENAKVELEQEQKTKQQLEK--------AKKLL 1306
Query: 3961 XXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAE 4140
+ ++ + + R + D K + D + E LR E+ + +AR+ G+A+ K
Sbjct: 1307 ETELHAVQGQLDDEKKGRDIVDRKRS--DLESELADLREDFEEAL-SARKVIGDAKSKL- 1362
Query: 4141 ESVNQQLEEL-------RKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMEL 4299
+S ++L+++ R+K V+ L+ Q +S+ + + +KI+++ +L
Sbjct: 1363 QSDYEELKKIAESDAAARQKAQEQVKILELQNADSQSLVQDAEAAAEKIERQRRTLEADL 1422
Query: 4300 ENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLL------- 4458
++V+ + +K + +F+ Q+A+ +++A L D ++ D+ + L
Sbjct: 1423 QDVQEKLDEEQKARVRFQKQLAKTDEELRQAKLKIDDLTNATSDQYIALKRLQEENSNQH 1482
Query: 4459 NEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQME 4638
E++ + E + +R+R+ + +L+D + ++ ++EK KR LE ++ D+ +
Sbjct: 1483 RELEALDEKTAQWNRLRKQAEVQLEDLKAQLEEAISAKLKVEKQKRDLENKVEDLESAAD 1542
Query: 4639 ELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEK 4818
N+ E + + EV + +++ KD EE +R L K + E +E +
Sbjct: 1543 VNSANVHPDELRKKQQEVDELKKQLAAEQERKTKD---EEVKRQLRKDVTTQEEAIEEYE 1599
Query: 4819 RGKSGAVSHRKKIENQIGELEQQLE---------------------------VANRLKEE 4917
R K A RKK+EN++ +L+ LE V+++ E+
Sbjct: 1600 RNKLNAERIRKKLENELEDLKASLESEQILRKKAELLAKPRGKEGATEIKPTVSSKSDED 1659
Query: 4918 YXXXXXXXXXXXXE-----------------YQIECEEARQAKEDIAALLREADRKFRAV 5046
+ E + E +E R ED + ++ RA+
Sbjct: 1660 FKKLTEELAVLKTELDGEKAWRGNAEKRERALRAENDELRGQLEDEVTAKDKTNKAKRAL 1719
Query: 5047 EAE----REQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXX 5214
E E ++QL E E L +A + + K E + L K+ +
Sbjct: 1720 EVEVEELKDQLDEVEESLQEAEEFKRRKDLELEEVKRK-----LEGEAELTLKMDELRKQ 1774
Query: 5215 XXXXQSNCELAIDKQRKAQVQLEQITTDLSMER-----------TLNQKTEAEKQSLERS 5361
N ++ ++++R+++ + E+I L E QKTE K+ +E
Sbjct: 1775 FEKDIENLKVELEEERRSRGEAERIRKRLEAENDDLNIKLDAEIKTRQKTEKAKKKIEGE 1834
Query: 5362 NRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLND 5541
R + ++ E ES ++++ LE ++ L++ L+ E ++K R + LE +L D
Sbjct: 1835 FRATRTRLDE-ESATKTQSENLAQKLEEEIAKLKEDLDNEVKQKALIERTRKSLELQLED 1893
Query: 5542 TTQQFEDEKRANEQAKELLEKSNLKNRNLRRQL---DEAEDEMSRERTK--------HRN 5688
T Q E E R A +L ++ + +LR Q+ DE E ++ ++T+ +N
Sbjct: 1894 TRTQMEVEARQRANADKLRRQAENELEDLREQVDAFDETEQDLLSDKTRLEVECEEARKN 1953
Query: 5689 VQREAD 5706
V RE++
Sbjct: 1954 VLRESE 1959
Score = 155 bits (393), Expect = 9e-36
Identities = 165/863 (19%), Positives = 365/863 (42%), Gaps = 16/863 (1%)
Frame = +1
Query: 2542 RTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDD 2721
+ D +++ L ++ + + E+KL+ VE L+QE + +L+
Sbjct: 1249 KADQDVKELKSNLENVSASRATLDQNLKATEEKLENAKVE-------LEQEQKTKQQLEK 1301
Query: 2722 IRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXX 2901
+ L+T EL + + D + + D
Sbjct: 1302 AKKLLET---ELHAVQGQLDDEKKGRDIVDRKRSDLESELADLREDFEEALSARKVIGDA 1358
Query: 2902 XXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKA 3081
+++ ++ Q A + L Q D + + A
Sbjct: 1359 KSKLQSDYEELKKIAESDAAARQKAQEQVKI-----------LELQNADSQSLVQDAEAA 1407
Query: 3082 KGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNN----- 3246
++E Q LE DL ++ E ++ + + +L + + L + K+++L N
Sbjct: 1408 AEKIERQRRTLEADLQDVQEKLDEEQKARVRFQKQLAKTDEELRQAKLKIDDLTNATSDQ 1467
Query: 3247 -----QLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
+L + + +L DE++A ++KQ + +++L+ +E +A+ K E
Sbjct: 1468 YIALKRLQEENSNQHRELEALDEKTAQWNRLRKQA---EVQLEDLKAQLEEAISAKLKVE 1524
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKR--AIEQIQHTMEGKIEE 3585
+R++ ++E ++ V+ A + D + +K +EV+ K+ A EQ + T + +++
Sbjct: 1525 KQKRDLENKVEDLESAA--DVNSANVHPDELRKKQQEVDELKKQLAAEQERKTKDEEVKR 1582
Query: 3586 QKAKFSRQVEELHDQIEQHKKQRSQLEKQ-QNQADQERADMAQEIALLQASRADIDKKRK 3762
Q K EE ++ E++K ++ K+ +N+ + +A + E L + +A++ K +
Sbjct: 1583 QLRKDVTTQEEAIEEYERNKLNAERIRKKLENELEDLKASLESEQILRK--KAELLAKPR 1640
Query: 3763 IHEAHLMEIQANLA-ESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAX 3939
E EI+ ++ +SDE + L ++L + ELD R E ++
Sbjct: 1641 GKEG-ATEIKPTVSSKSDEDFKKLTEELAVLKTELDGEKAWRGNAEKRERALRAENDELR 1699
Query: 3940 XXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAG 4119
+ K A +L+D+ + + + +EAE + + E+ ++
Sbjct: 1700 GQLEDEVTAKDKTNKAKRALEVEVEELKDQLDEVEESLQEAEEFKRRKDLELEEVKR--- 1756
Query: 4120 EARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMEL 4299
+ + E + +++ELRK+ +D+E+L+ +LEE ++ + +K+++ E +D +++L
Sbjct: 1757 --KLEGEAELTLKMDELRKQFEKDIENLKVELEEERRSRGEAERIRKRLEAENDDLNIKL 1814
Query: 4300 ENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMK 4479
+ + + +EK +KK E + R + + + + E + L ++D
Sbjct: 1815 DAEIKTRQKTEKAKKKIEGEFRATRTRLDEESATKTQSENLAQKLEEEIAKLKEDLDNEV 1874
Query: 4480 EHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQ 4659
+ +R R+SL+ +L+D+ + + + +K +R E EL D+R Q++ ++ Q
Sbjct: 1875 KQKALIERTRKSLELQLEDTRTQMEVEARQRANADKLRRQAENELEDLREQVDAFDETEQ 1934
Query: 4660 IAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAV 4839
+ RLEV + + R ++ AE R + +++ +L + + E ++
Sbjct: 1935 DLLSDKTRLEVECEEARKNVLRESEAREA-AELARTRIQRELAELREKYDEEVILRTNLE 1993
Query: 4840 SHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLR 5019
RKK + + ++QLE+ ++L+ + Q +A + K + AL +
Sbjct: 1994 RTRKKTDADYEDAKEQLELESKLRAKLEREVKAAAAGTKLLQTAKADADKLKARVQALEK 2053
Query: 5020 -EAD-RKFRAVEAEREQLREANE 5082
EAD +K +A E E R A E
Sbjct: 2054 MEADYKKLQARCTEEEDARRAAE 2076
Score = 68.9 bits (167), Expect = 1e-09
Identities = 66/293 (22%), Positives = 135/293 (45%), Gaps = 35/293 (11%)
Frame = +1
Query: 3031 TTQLLDHEERAK-HGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDH 3207
T LD E K +LE ++ +L++DL+ E + K+ +E+ ++ L +LED++
Sbjct: 1838 TRTRLDEESATKTQSENLAQKLEEEIAKLKEDLDNEVKQKALIERTRKSLELQLEDTRTQ 1897
Query: 3208 L---AEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDM 3378
+ A + ++L Q E+L+ Q+ +DE + L+ + R ++ +E R+++
Sbjct: 1898 MEVEARQRANADKLRRQAENELEDLREQVDAFDETEQD--LLSDKTR-LEVECEEARKNV 1954
Query: 3379 ETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQ 3558
E AR AE+ R + +L +++ ++V T L+ + D + K +E ++
Sbjct: 1955 LRESEAREAAELARTRIQRELAELREKYDEEVILRTNLERTRKKTDADYEDAKEQLE-LE 2013
Query: 3559 HTMEGKIE-EQKA----------------KFSRQVEELHDQIEQHKKQRSQLEKQQNQAD 3687
+ K+E E KA K +V+ L +KK +++ ++++
Sbjct: 2014 SKLRAKLEREVKAAAAGTKLLQTAKADADKLKARVQALEKMEADYKKLQARCTEEEDARR 2073
Query: 3688 QERADMAQEIALLQASRA--------------DIDKKRKIHEAHLMEIQANLA 3804
+ + IA L +RA D++K++K +E ++QANLA
Sbjct: 2074 AAENEKKKAIADLNEARADVLFYQQQAEKIRTDVEKEKKSNE----DLQANLA 2122
>gi|38079956|ref|XP_356900.1| similar to KIAA1000 protein [Mus
musculus]
Length = 2037
Score = 929 bits (2401), Expect = 0.0
Identities = 598/1924 (31%), Positives = 994/1924 (51%), Gaps = 27/1924 (1%)
Frame = +1
Query: 37 AVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETND-EVLVELVDTSRQVTISRDDVQK 213
++A L + +K CWVPD ++ +K +D +V+VE D + I D +Q+
Sbjct: 27 SMAHSPPLGKASGKKKCWVPDGKNAYIEAEVKESGDDGQVIVETRD-GEIMRIKEDKLQQ 85
Query: 214 ANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDL 393
NP + + IED+S L YLNEASVLH L+ RY +IYTYSG+FCV INPYK LP+Y +++
Sbjct: 86 MNPEELEMIEDLSMLLYLNEASVLHTLRRRYDHWMIYTYSGIFCVAINPYKWLPVYQKEV 145
Query: 394 IEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHV 573
+ +K K+R E+PPHIFA+A+ A++ ML+ E+QSI+ TGESG+GKT NTK +IQY A +
Sbjct: 146 MAAYKRKRRSEVPPHIFAVANRAFQDMLRNGENQSIVFTGESGSGKTVNTKLIIQYFATM 205
Query: 574 AGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGK 753
A + K +G LE Q+++ NP+LEAFGN+KT KNDNSSRFGK
Sbjct: 206 AAISEPK-----------------KKLGNLEDQIVKMNPLLEAFGNAKTQKNDNSSRFGK 248
Query: 754 FIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGV 933
IRI+F G +S A+I+ Y LEKSRV+ Q ER++HIFYQIL G +
Sbjct: 249 LIRIHFGARGTLSFADIQIYFLEKSRVVYQQPGERNYHIFYQILSGNQELRNMLLVSTNP 308
Query: 934 DNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQE 1113
++ + + ++DD +EF +T ++ ++GF DE ++V A++ GNL+F +
Sbjct: 309 SDFHICSCGVVAVESLDDAKEFLATEKAIDVLGFLPDEKFGCYKLVGAIMHFGNLKFKRN 368
Query: 1114 KKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAI 1293
+ +Q K L+G+ EL K + PRIKVG E+V ++QN +Q +AV A+
Sbjct: 369 LREEQLEADGTENADKAAFLMGIHASELLKGLIYPRIKVGNEYVTRSQNLQQVTYAVGAL 428
Query: 1294 AKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQ 1473
+++ YER+F+WLV R+N+ LD F+GILD GFEI D NS EQ+CIN+TNEKLQ
Sbjct: 429 SQSIYERMFQWLVARMNQVLD-AKLTSHFFVGILDTTGFEILDYNSLEQLCINFTNEKLQ 487
Query: 1474 QLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDK 1653
Q FN +FILEQEEY++EG++W ID+GLD+Q ID IEKPMG+ ++L+EEC+ PKA D+
Sbjct: 488 QFFNQQLFILEQEEYRKEGLDWLSIDYGLDVQACIDFIEKPMGIFSILEEECMLPKATDQ 547
Query: 1654 SFVEKLQKTH-NKHPKFIVPDMRSKS---HFAVVHYAGRVDYSADQWLMKNMDPLNENVV 1821
F KL H K F P K+ HF + HYAG V Y+ W+ KN LNE VV
Sbjct: 548 MFKTKLFDHHFGKSAYFQTPTSPEKNFEVHFELAHYAGVVPYNISGWIGKNKGLLNETVV 607
Query: 1822 GLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTL 2001
L+Q S++ +A ++ AG + TAF ++ G + + E + KLMT L
Sbjct: 608 ALLQKSSNKVLANLFTKDIIAG---SASKATAFKFKA-GGNDSQWNYVCWENINKLMTDL 663
Query: 2002 RNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRY 2181
++T+PHFVRCI PN K G ++ LVL+QLRCNGVLEGIR+C + FP+ + + +F+ RY
Sbjct: 664 KSTAPHFVRCINPNKNKIPGVMDPFLVLQQLRCNGVLEGIRVCCEAFPSWMLYDDFKQRY 723
Query: 2182 EILTPDVIPKN-FIDGKESVRKMITALDIDTNLYRIGQSKV---FFRTGVLAHLEEERDL 2349
IL P + K+ F+ +++ +++ L+ID Y+ G +KV +L LEE RD
Sbjct: 724 WILNPRIFSKSKFVSSRKATEEVLDFLEIDHPHYQCGVTKVTQNVQEAFILDQLEERRDE 783
Query: 2350 KLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPL 2529
K++ + FQA+ RG L R + N A++ ++N W LF K+KPL
Sbjct: 784 KISKVFTLFQARARGKLMRITFQKILEERDALALIQENIRAFIAVKNCPWMGLFFKIKPL 843
Query: 2530 LQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSA 2709
+ +EI +E ++ L E E + K ++ E+ ++ QLQ E E A
Sbjct: 844 AKSVGAGEEIAGLKEECAQLQKALESSESQREELKTKQVSLVQEKNDLRLQLQAEQETLA 903
Query: 2710 ELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXX 2889
++ L ELE + ++ ++ RK + +
Sbjct: 904 NSEEQCESLIKSKVELEVKIKELSRQVEEEEEINSELTARGRKLEDECSELKKEIYDLEA 963
Query: 2890 XXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKH 3069
K + + QL EE+ +
Sbjct: 964 ILAKSEKGKCAAEHKVRNLTEEVHSLNEEVSKLSRVVKDAQETQQQTQEQLHIEEEKLSN 1023
Query: 3070 GVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQ 3249
KA +L Q+ LE DL RER+ + + E+ KRKL EL+ +++ ++L Q
Sbjct: 1024 MSKANLKLAQQIDVLEGDLERERKARMKCEREKRKLQDELKMNQEGAENLESSRQKLAEQ 1083
Query: 3250 LMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREV 3429
L K++ E+ ++ + E V+ +QK ++++QT I L+E++E+ER R K E + ++
Sbjct: 1084 LRKKEFEMGQMNSKVENEKNQVSQLQKMVKELQTHILNLKEELESERTIRAKVEREKGDL 1143
Query: 3430 VAQLEKVKGDVLDKVDEA--TMLQDLMSRKDEEVNATK--RAIEQIQHTMEGKIEEQKAK 3597
V LE D+ ++++EA T L + K +E K +E+ E K +
Sbjct: 1144 VQDLE----DLNERLEEAGGTSLAQMEITKQQEARFQKLHHDMEETTRHFEATSASLKKR 1199
Query: 3598 FSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAH 3777
+ + EL Q+E ++ R LE+ ++ + D+ + + ++A+ +K ++E
Sbjct: 1200 HAENLAELEGQVEHLQQVRLVLEQDKSDLQLQVDDLLNRVDQMARAKANAEKLCGLYERR 1259
Query: 3778 LMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXX 3957
L E L E + L Q + + E + EE+E + + R +
Sbjct: 1260 LNEANTKLDEVTQLAHDLTTQKTKLQSESGEFFKRLEEKEALISQLSREKSNFTRQVEEL 1319
Query: 3958 XXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKA 4137
+R + A + + + + + L ++ EE + ++A L + + + + R K
Sbjct: 1320 RAQLEEESRSQSALSHALQSAKHDYDLLREQYEEEQEVKAELHRALSKGNKETVQWRAKY 1379
Query: 4138 EESVNQQLEELRKKNLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENV 4308
E Q+ E+L + + LQ+ E EV+ + + +++ ++Q EL D+ +L
Sbjct: 1380 EHDAMQRTEDLEEAKKKLAIRLQEAAEAMEVSNAKNASLERARHRLQLELGDALSDLGKA 1439
Query: 4309 RASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHL 4488
R+ ++Q Q +++ + K LD + +ETR LS +EV ++
Sbjct: 1440 RSVAAALGQKQ-----QHSDKALTSWKQKLDETQELLQASQKETRALS--SEVLTFRQAC 1492
Query: 4489 EESDRVRRSLQQELQD------SISNKDDFG-KNVHELEKAKRSLEAELNDMRVQMEELE 4647
EES + +L+++ QD S++N+ G KN+ E+EKAK+ +E E +++V++EE E
Sbjct: 1493 EESTEAQETLKRQNQDLQEQICSLTNQVREGIKNLAEVEKAKKLIEQEKTEVQVRLEETE 1552
Query: 4648 DNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGK 4827
L+ E LR ++ K+E +R +S K+ EAE R + + L++ L+ E +
Sbjct: 1553 GALERNESKILRFQLELSEAKAELERKLSEKEEEAERLREKHQQAMGSLQSNLDLEASSR 1612
Query: 4828 SGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIA 5007
A RKK+E + E+E QL ANR + + + +++ +D+
Sbjct: 1613 IEATRLRKKMEGDLKEMEIQLCAANRQVSQMTRALGQLQGQMKDLHQQLDDSIYQNKDLK 1672
Query: 5008 ALLREADRKFRAVEAEREQLREANE----GLMQARKQXXXXXXXXXXXRAKGGGISSEEK 5175
+ A+++ +++E E+LR E G A K+ + + S +K
Sbjct: 1673 EQVALAEQRTVLLQSELEELRTLQEQTERGRKLAEKELLEATERINLFHTQNTSLLS-QK 1731
Query: 5176 RRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLE 5355
++LEA +AQ C+ A +K +K + ++ +L E+ N E ++++E
Sbjct: 1732 KKLEADVAQVQKEAGEMLQACQKAEEKAKKTAAEAANMSEELKKEQDTNAHLERMRKNME 1791
Query: 5356 RSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRL 5535
++ +D + ++ E E A ++ Q+ LE++V+ LE +L E + A R ARRLE+ +
Sbjct: 1792 QTIKDLQKRLDEAEQTAVLGSKKQIQKLESRVRDLEGELESEVRRSAEAQREARRLERGI 1851
Query: 5536 NDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLL 5715
+ T Q E++K+ + + L +K LK ++ ++Q++ AE + ++ +K++ Q E ++
Sbjct: 1852 KELTYQAEEDKKNLSRMQALSDKLQLKVQSYKQQVEAAEAQANQYLSKYKKQQHELNEAK 1911
Query: 5716 DANE 5727
+ E
Sbjct: 1912 ERAE 1915
Score = 66.6 bits (161), Expect = 7e-09
Identities = 105/527 (19%), Positives = 209/527 (38%), Gaps = 14/527 (2%)
Frame = +1
Query: 4201 LQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVA 4380
LQK LE SE +E + + + QE D ++L+ + + +SE++ + E V
Sbjct: 863 LQKALESSESQREELKTKQVSLVQEKNDLRLQLQAEQETLANSEEQCESLIKSKVELEVK 922
Query: 4381 VQKALLDRDAMSQELRDRE--TRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKD 4554
+++ L R +E + E R L +E +K+ + + + + ++ +
Sbjct: 923 IKE--LSRQVEEEEEINSELTARGRKLEDECSELKKEIYDLEAILAKSEKGKCAAEHKVR 980
Query: 4555 DFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAIS 4734
+ + VH L + L + D + ++ ++ L I E+ + N L + D +
Sbjct: 981 NLTEEVHSLNEEVSKLSRVVKDAQETQQQTQEQLHIEEEKLSNMSKANLKLAQQID--VL 1038
Query: 4735 NKDVEAEEKRRGLL-KQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLK 4911
D+E E K R ++ R L++EL+ + G S R+K+ Q+ + E ++ N
Sbjct: 1039 EGDLERERKARMKCEREKRKLQDELKMNQEGAENLESSRQKLAEQLRKKEFEMGQMNSKV 1098
Query: 4912 EEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRA-VEAER----EQLREA 5076
E E Q KE++ E++R RA VE E+ + L +
Sbjct: 1099 ENEKNQVSQLQKMVKELQTHI---LNLKEEL-----ESERTIRAKVEREKGDLVQDLEDL 1150
Query: 5077 NEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDK 5256
NE L +A GG S ++ I K
Sbjct: 1151 NERLEEA------------------GGTSL-----------------------AQMEITK 1169
Query: 5257 QRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAA 5436
Q++A+ Q ME T + EA SL++ + + + ELE + + ++
Sbjct: 1170 QQEARFQ----KLHHDMEET-TRHFEATSASLKKRHAE---NLAELEGQVEHLQQVRLVL 1221
Query: 5437 ------LEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELL 5598
L+ +V L ++++ + K A + E+RLN+ + ++ +
Sbjct: 1222 EQDKSDLQLQVDDLLNRVDQMARAKANAEKLCGLYERRLNEANTKLDEVTQLAHDLTTQK 1281
Query: 5599 EKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTR 5739
K ++ ++L+E E +S+ + N R+ ++L E+ +R
Sbjct: 1282 TKLQSESGEFFKRLEEKEALISQLSREKSNFTRQVEELRAQLEEESR 1328
Score = 55.1 bits (131), Expect = 2e-05
Identities = 72/346 (20%), Positives = 137/346 (38%), Gaps = 1/346 (0%)
Frame = +1
Query: 4711 SESDRA-ISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQ 4887
SES R + K V +++ L Q++ + L N + + + ++E +I EL +Q
Sbjct: 870 SESQREELKTKQVSLVQEKNDLRLQLQAEQETLANSEEQCESLIKSKVELEVKIKELSRQ 929
Query: 4888 LEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQL 5067
+E + E + + EC E ++ D+ A+L ++++ A E + L
Sbjct: 930 VEEEEEINSELTARGR-------KLEDECSELKKEIYDLEAILAKSEKGKCAAEHKVRNL 982
Query: 5068 REANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELA 5247
E L + + + + + E+ E K++ ++N +LA
Sbjct: 983 TEEVHSLNEEVSKLSRVVKDAQETQQQ----TQEQLHIEEEKLSNMS------KANLKLA 1032
Query: 5248 IDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQ 5427
Q++ + DL ER K E EK+ L+ ++ + GA++
Sbjct: 1033 --------QQIDVLEGDLERERKARMKCEREKRKLQD-------ELKMNQEGAEN----- 1072
Query: 5428 MAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKS 5607
LE+ Q L +QL R+ E + + E+EK Q ++++++
Sbjct: 1073 ---LESSRQKLAEQL--------------RKKEFEMGQMNSKVENEKNQVSQLQKMVKEL 1115
Query: 5608 NLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
NL+ +L+ ERT V+RE DL+ E L L
Sbjct: 1116 QTHILNLKEELES-------ERTIRAKVEREKGDLVQDLEDLNERL 1154
Score = 52.0 bits (123), Expect = 2e-04
Identities = 50/244 (20%), Positives = 110/244 (44%), Gaps = 9/244 (3%)
Frame = +1
Query: 3052 EERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKL---LAELEDSKDHLAEKM 3222
+E+ + G K E +L E + +N + L K+KL +A+++ + +
Sbjct: 1696 QEQTERGRKLA---EKELLEATERINLFHTQNTSLLSQKKKLEADVAQVQKEAGEMLQAC 1752
Query: 3223 GKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQM----RDMQTTIDELREDMET-E 3387
K EE + + +L + + +A++ M+K M +D+Q +DE +
Sbjct: 1753 QKAEEKAKKTAAEAANMSEELKKEQDTNAHLERMRKNMEQTIKDLQKRLDEAEQTAVLGS 1812
Query: 3388 RNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTM 3567
+ K E R++ +LE + EA L+ + + K+ + ++Q +
Sbjct: 1813 KKQIQKLESRVRDLEGELESEVRRSAEAQREARRLERGIKELTYQAEEDKKNLSRMQ-AL 1871
Query: 3568 EGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQ-EIALLQASRAD 3744
K++ + + +QVE Q Q+ + + + + N+A +ERA+ A+ ++ L+A +
Sbjct: 1872 SDKLQLKVQSYKQQVEAAEAQANQYLSKYKKQQHELNEA-KERAEAAESQVNKLRAKAKE 1930
Query: 3745 IDKK 3756
++KK
Sbjct: 1931 LEKK 1934
>gi|6682319|emb|CAB64662.1| myosin heavy chain [Mytilus
galloprovincialis]
Length = 1705
Score = 923 bits (2386), Expect = 0.0
Identities = 554/1681 (32%), Positives = 904/1681 (52%), Gaps = 16/1681 (0%)
Frame = +1
Query: 715 KTVKNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGC 894
KTV+N+NSSRFGKFIRI+F +G I+GA+IE YLLEKSRV Q ER +HIFY +L
Sbjct: 1 KTVRNNNSSRFGKFIRIHFGPTGKIAGADIETYLLEKSRVTFQQSAERDYHIFYMLLSNA 60
Query: 895 SAKEKSEYLLEGVDNYRFLVNRG-ITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVV 1071
K L+ +N+G +T+ +DDV+E +S I+GF+ +E +S+ +
Sbjct: 61 YPKYHEMMLITPDPALFSFINQGALTVDGIDDVEEMKIADSSFDILGFSYEEKTSLYKCT 120
Query: 1072 SAVLLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNK 1251
++V+ +G ++F Q + +QA +K LLG+ +L K+ L+P+IKVG E V +
Sbjct: 121 ASVMHMGEMKFKQRPREEQAEADGTADAEKAAFLLGVNSNDLLKSLLKPKIKVGSEVVTQ 180
Query: 1252 AQNQEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINS 1431
+ +EQ ++V A+AK+ Y+R+FKWLVTR+N++LD +++ FIG+LDIAGFEIF+ N+
Sbjct: 181 GRTREQVLYSVSAMAKSLYDRMFKWLVTRVNQTLDTKNKRNY-FIGVLDIAGFEIFNYNT 239
Query: 1432 FEQICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLA 1611
FEQ+CINYTNE+LQQ FN+ MFILEQEEY++EGI W+FIDFG+DLQ IDLIEKPMG+L+
Sbjct: 240 FEQLCINYTNERLQQFFNHHMFILEQEEYKKEGIVWEFIDFGMDLQACIDLIEKPMGILS 299
Query: 1612 LLDEECLFPKANDKSFVEKLQKTH-NKHPKFIVPDMRSK----SHFAVVHYAGRVDYSAD 1776
+L+EEC+FPKA+DKSF +KL H K P F P SK S F + HYAG V YS
Sbjct: 300 ILEEECMFPKADDKSFKDKLFANHLGKSPNFGRPGNASKGKGQSDFELHHYAGIVPYSTV 359
Query: 1777 QWLMKNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTV 1956
WL KN DP+NE VV L+ +S + V ++ + E T + + F+T+
Sbjct: 360 GWLEKNKDPINETVVELLSHSKEHLVQTLFAQNK-------EAETTGTHKKRKSSAFQTI 412
Query: 1957 SQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQ 2136
S LHKE L KLM L +T PHFVRCIIPN K+ G I+++LVL QL+CNGVLEGIRICR+
Sbjct: 413 SALHKESLNKLMKNLYSTHPHFVRCIIPNELKQPGLIDAHLVLNQLQCNGVLEGIRICRK 472
Query: 2137 GFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTG 2316
GFPNR+ + EF+ RY IL+P+ IP+ F DGK+ K++ AL +D YR+G +KVFF+ G
Sbjct: 473 GFPNRIIYSEFKQRYSILSPNAIPQGFTDGKQVTEKVLLALQLDPAEYRLGTTKVFFKAG 532
Query: 2317 VLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQ 2496
VL LE+ RD L+ +I NFQA R +L R+ Y N +L LRNWQ
Sbjct: 533 VLGMLEDMRDECLSKIISNFQAHIRAYLIRKSYKKLCDQRVGLSVIQRNIRKWLILRNWQ 592
Query: 2497 WWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQ 2676
WW+L+ KVKPLL + R ++E++ K +E+ +E L K E +E E + ++ ++ +
Sbjct: 593 WWKLYIKVKPLLNIARAEEEMKKKIEEMGKLREDLAKCERLKKELEVQNVTLLEQKNDLY 652
Query: 2677 EQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVR 2856
QLQ E + A+L++ +L T+ + E + +M +RL +RK
Sbjct: 653 LQLQTEQDAVADLEERVEKLVTQKADFESQIKEMEERLLDEEDAAAELEVIKRKMEGEND 712
Query: 2857 DXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTT 3036
+ +KT D D
Sbjct: 713 ELKKDIEDLENSLAKSEQEKTTKDNQIKTLQDEMAQQDDIISKLNRDKKGMDEDHKRTLD 772
Query: 3037 QLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAE 3216
L E++ H K K +LE+ L ELE L RE++ + ++E+ KRK+ +L+ +++ + +
Sbjct: 773 ALQKEEDKVNHLSKLKQKLESTLDELEDGLEREKKVRGDVEKAKRKIEQDLKATQEAVED 832
Query: 3217 KMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNA 3396
L K+D E +R +++ + + +Q++++++ I+EL E++E ER A
Sbjct: 833 LERVKRGLEETNRKKDAENAALSSRLEDDQSLIAQLQRKIKELLARIEELEEELEAERAA 892
Query: 3397 RNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEG 3573
R K + R E+ +LE + + LD+ AT Q +L ++++E+ +R +E+ E
Sbjct: 893 RTKVDKQRAEIARELEDL-SERLDEAGGATSAQIELNKKREQELLKLRRDLEETTLQHEA 951
Query: 3574 KIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK 3753
++ + K E+ DQI+Q +K +S+ EK++ Q E D+ ++ + ++ +K
Sbjct: 952 QVSSLRKKQQDAANEMADQIDQLQKAKSKTEKERQQFKSECDDLQSQLQHISKNKGVSEK 1011
Query: 3754 KRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLAT 3933
K E + E+Q +S+ + L Q + + E ++ + E+ EH + + +
Sbjct: 1012 MAKSLENTIAELQHKCDDSNRNVNDLNTQKAKMQAENANIIQQLEDVEHQCSAITKERNA 1071
Query: 3934 AXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQG 4113
TR + R L + + L + EE + +A L++ + A
Sbjct: 1072 MQSQLDEMRAALEEETRARQKLQGDIRNLNSDLDGLRESNEEEQEAKAELQRLLSKANNE 1131
Query: 4114 AGEARRKAE-ESVN--QQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELED 4284
A + R K E E N ++LEE R+K ++ ++ E + + ++K ++ ELED
Sbjct: 1132 AQQWRVKYESEGANKAEELEEARRKLQAKLQEAEQNAEAANAKVSSLEKAKNRLTGELED 1191
Query: 4285 SSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNE 4464
+++E A+ EK+Q+ F+ + E + V + + +E R + +
Sbjct: 1192 LGIDVERANANANSLEKKQRAFDKTIQEWQAKVTDLQSELENAQKEARSYSAELFRCKAQ 1251
Query: 4465 VDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEEL 4644
+ ++ +E R ++L +E+ + + G++VHE+EKAKR LE E +++ +EE
Sbjct: 1252 YEESQDSVEALRRENKNLAEEIHELTEQLSEGGRSVHEVEKAKRRLEMEKEELQAALEEA 1311
Query: 4645 EDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRG 4824
E L+ E +R ++ ++SE +R + KD E E RR + + ++ LE E +G
Sbjct: 1312 ESALEQEEAKVMRGQLEISNVRSEIERRLQEKDEEFENTRRNHQRALDSMQASLEAEAKG 1371
Query: 4825 KSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDI 5004
K+ A+ +KK+E I ELE L+ +NR K E E Q + EE ++ +E++
Sbjct: 1372 KAEAMRIKKKLEQDINELEIALDSSNRAKAELEKNIKRYQQQVSEMQRQIEEEQRQREEV 1431
Query: 5005 AALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSE----- 5169
A+R+ + E E+LR A E +ARK + +S+E
Sbjct: 1432 RESYNMAERRCNMLSGEVEELRTALEQAERARK---GAENELFEANDRVNELSAEVQSAQ 1488
Query: 5170 -EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQ 5346
KR+LE I + A ++ R+A ++ +L E+ +Q+ E ++
Sbjct: 1489 SSKRKLEGDIQAMQSDLDEMNNEVRNADERARRANDDSARLADELRSEQEHSQQIEKFRK 1548
Query: 5347 SLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLE 5526
SLE +D + ++ E E+ A + +A LE +V+ LE +L+ E + + R+ +
Sbjct: 1549 SLESQVKDLQVRLEEAEAQALKGGKKMIAKLEQRVRELEGELDSEQRRHAETQKHMRKAD 1608
Query: 5527 KRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREAD 5706
+RL + Q +++++ E E++EK N K + +RQ++EAE+ + K+R VQ+E +
Sbjct: 1609 RRLKEIAFQADEDRKNQENLNEMIEKLNNKLKTYKRQVEEAEEIAAINLAKYRKVQQELE 1668
Query: 5707 D 5709
D
Sbjct: 1669 D 1669
Score = 176 bits (445), Expect = 8e-42
Identities = 191/941 (20%), Positives = 403/941 (42%), Gaps = 41/941 (4%)
Frame = +1
Query: 3052 EERAKHGVKAKGRLENQLHELEQDLNRERQYKS-ELEQHKRKLLAELEDSKDHLAEKMGK 3228
EE K ++ G+L L + E+ L +E + ++ L + K L +L+ +D +A+ +
Sbjct: 610 EEEMKKKIEEMGKLREDLAKCER-LKKELEVQNVTLLEQKNDLYLQLQTEQDAVADLEER 668
Query: 3229 VEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKA 3408
VE+L Q + +++ R +E ++ R M+ DEL++D+E N+ K+
Sbjct: 669 VEKLVTQKADFESQIKEMEERLLDEEDAAAELEVIKRKMEGENDELKKDIEDLENSLAKS 728
Query: 3409 EMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQ 3588
E + Q++ ++ ++ + D + L DE+ T A+++ + + + +
Sbjct: 729 EQEKTTKDNQIKTLQDEMAQQDDIISKLNRDKKGMDEDHKRTLDALQKEEDKVN-HLSKL 787
Query: 3589 KAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIH 3768
K K ++EL D +E+ KK R +EK + + +Q+ + + L+ + +++ +
Sbjct: 788 KQKLESTLDELEDGLEREKKVRGDVEKAKRKIEQDLKATQEAVEDLERVKRGLEETNRKK 847
Query: 3769 EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXX 3948
+A + + L E ++LI QL+R EL L R+ E EE A R
Sbjct: 848 DAENAALSSRL----EDDQSLIAQLQRKIKEL--LARIEELEEELEAERAAR-------- 893
Query: 3949 XXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEAR 4128
T++ AR+LED L DE A + L K+ Q + R
Sbjct: 894 ----------TKVDKQRAEIARELEDLSERL-DEAGGATSAQIELNKK---REQELLKLR 939
Query: 4129 RKAEESVNQ---QLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMEL 4299
R EE+ Q Q+ LRKK + Q+++ + AK + + +++ + E +D +L
Sbjct: 940 RDLEETTLQHEAQVSSLRKKQQDAANEMADQIDQLQKAKSKTEKERQQFKSECDDLQSQL 999
Query: 4300 ENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMK 4479
+++ + SEK K E+ +AE + + + + ++ + + +++ +++ ++
Sbjct: 1000 QHISKNKGVSEKMAKSLENTIAELQHKCDDSNRNVNDLNTQKAKMQAENANIIQQLEDVE 1059
Query: 4480 EHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQ 4659
+ R ++Q +L + + ++ + +L+ R+L ++L+ +R EE ++
Sbjct: 1060 HQCSAITKERNAMQSQLDEMRAALEEETRARQKLQGDIRNLNSDLDGLRESNEEEQEAK- 1118
Query: 4660 IAEDARLRLEVTNQA----LKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGK 4827
AE RL + N+A +K ES+ A NK E EE RR L ++++ E E
Sbjct: 1119 -AELQRLLSKANNEAQQWRVKYESEGA--NKAEELEEARRKLQAKLQEAEQNAEAANAKV 1175
Query: 4828 SGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIA 5007
S + ++ ++ +L +E AN E+Q + + + E+
Sbjct: 1176 SSLEKAKNRLTGELEDLGIDVERANANANSLEKKQRAFDKTIQEWQAKVTDLQSELENAQ 1235
Query: 5008 ALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSE---EKR 5178
R + +A+ E+ +++ E L + K ++GG E KR
Sbjct: 1236 KEARSYSAELFRCKAQYEESQDSVEALRRENKNLAEEIHELTEQLSEGGRSVHEVEKAKR 1295
Query: 5179 RLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLER 5358
RLE + + +S E K + Q+++ + +++ ER L +K E + +
Sbjct: 1296 RLEMEKEELQAALEEAESALEQEEAKVMRGQLEISNVRSEI--ERRLQEKDEEFENTRRN 1353
Query: 5359 SNRDYKAKITELESGAQSRARAQMAA--LEAKVQYLEDQLNVEGQEKTAANRAARRLEKR 5532
R + LE+ A+ +A A LE + LE L+ + K + +R +++
Sbjct: 1354 HQRALDSMQASLEAEAKGKAEAMRIKKKLEQDINELEIALDSSNRAKAELEKNIKRYQQQ 1413
Query: 5533 LNDTTQQFEDEKR----------------------------ANEQAKELLEKSNLKNRNL 5628
+++ +Q E+E+R A EQA+ + + +
Sbjct: 1414 VSEMQRQIEEEQRQREEVRESYNMAERRCNMLSGEVEELRTALEQAERARKGAENELFEA 1473
Query: 5629 RRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
+++E E+ ++ R ++ + + +++ E+ N
Sbjct: 1474 NDRVNELSAEVQSAQSSKRKLEGDIQAMQSDLDEMNNEVRN 1514
Score = 168 bits (425), Expect = 2e-39
Identities = 182/927 (19%), Positives = 396/927 (42%), Gaps = 66/927 (7%)
Frame = +1
Query: 3166 KRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRD- 3342
K +L LED +D K+ N Q R ++ + ++ ++++Q+ +R
Sbjct: 530 KAGVLGMLEDMRDECLSKIIS----NFQAHIRAYLIRKSYKKLCDQRVGLSVIQRNIRKW 585
Query: 3343 ----------MQTTIDELREDMETERNARNKAEMTR--REVVAQLEKVKGDVLDKVDEAT 3486
+ + L E + K E RE +A+ E++K ++ +V T
Sbjct: 586 LILRNWQWWKLYIKVKPLLNIARAEEEMKKKIEEMGKLREDLAKCERLKKEL--EVQNVT 643
Query: 3487 MLQ---DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRS 3657
+L+ DL + E +A E+++ K+ QKA F Q++E+ +++ + +
Sbjct: 644 LLEQKNDLYLQLQTEQDAVADLEERVE-----KLVTQKADFESQIKEMEERLLDEEDAAA 698
Query: 3658 QLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDE------- 3816
+LE + + + E ++ ++I L+ S A ++++ + + +Q +A+ D+
Sbjct: 699 ELEVIKRKMEGENDELKKDIEDLENSLAKSEQEKTTKDNQIKTLQDEMAQQDDIISKLNR 758
Query: 3817 --------HKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXX 3972
HKRTL D L++ D+++HL++++++ E ++ L
Sbjct: 759 DKKGMDEDHKRTL-DALQKEEDKVNHLSKLKQKLESTLDELEDGLEREKKVR-------- 809
Query: 3973 XXTRLKIANINRA-RQLEDEKNALLDEKEEAEGLRAHLEKEIHA--ARQGAGEARRKAEE 4143
++ +A R++E + A + E+ E ++ LE+ A A +R + ++
Sbjct: 810 -------GDVEKAKRKIEQDLKATQEAVEDLERVKRGLEETNRKKDAENAALSSRLEDDQ 862
Query: 4144 SVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHR 4323
S+ QL+ K+ L +E L+++LE A+ ++ + + +I +ELED S L+ +
Sbjct: 863 SLIAQLQRKIKELLARIEELEEELEAERAARTKVDKQRAEIARELEDLSERLDEAGGATS 922
Query: 4324 DSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLS-LLNEVDIMKEHLEESD 4500
+ KK E ++ + R +++ L +A LR ++ + + +++D +++ +++
Sbjct: 923 AQIELNKKREQELLKLRRDLEETTLQHEAQVSSLRKKQQDAANEMADQIDQLQKAKSKTE 982
Query: 4501 RVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARL 4680
+ R+ + E D S KN EK +SLE + +++ + ++ N+
Sbjct: 983 KERQQFKSECDDLQSQLQHISKNKGVSEKMAKSLENTIAELQHKCDDSNRNVN------- 1035
Query: 4681 RLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIE 4860
++ Q K +++ A +++Q+ D+E++ S R ++
Sbjct: 1036 --DLNTQKAKMQAENA-------------NIIQQLEDVEHQC-------SAITKERNAMQ 1073
Query: 4861 NQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFR 5040
+Q+ E+ LE R +++ + EE ++AK ++ LL +A+
Sbjct: 1074 SQLDEMRAALEEETRARQKLQGDIRNLNSDLDGLRESNEEEQEAKAELQRLLSKANN--- 1130
Query: 5041 AVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXX 5220
EA++ +++ +EG +A + E +R+L+AK+ +
Sbjct: 1131 --EAQQWRVKYESEGANKAEEL-------------------EEARRKLQAKLQEAEQNAE 1169
Query: 5221 XXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELES 5400
+ + + +LE + D+ E ++++ +++ ++++AK+T+L+S
Sbjct: 1170 AANAKVSSLEKAKNRLTGELEDLGIDVERANANANSLEKKQRAFDKTIQEWQAKVTDLQS 1229
Query: 5401 ---GAQSRARAQMAAL-EAKVQYLEDQLNVEGQEKTAAN--------------------- 5505
AQ AR+ A L K QY E Q +VE + N
Sbjct: 1230 ELENAQKEARSYSAELFRCKAQYEESQDSVEALRRENKNLAEEIHELTEQLSEGGRSVHE 1289
Query: 5506 --RAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLR----RQLDEAEDEMSR 5667
+A RRLE + E+ + A EQ + + + L+ N+R R+L E ++E
Sbjct: 1290 VEKAKRRLEMEKEELQAALEEAESALEQEEAKVMRGQLEISNVRSEIERRLQEKDEEFEN 1349
Query: 5668 ERTKHRNVQREADDLLDANEQLTRELM 5748
R H+ L+A + E M
Sbjct: 1350 TRRNHQRALDSMQASLEAEAKGKAEAM 1376
Score = 116 bits (291), Expect = 6e-24
Identities = 151/748 (20%), Positives = 301/748 (40%), Gaps = 66/748 (8%)
Frame = +1
Query: 2554 EIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGR 2733
+ +++ D+L++ + + K + + K L+ I E +Q + + N +L+ + +
Sbjct: 987 QFKSECDDLQSQLQHISKNKGVSEKMAKSLENTIAE---LQHKCDDSNRNVNDLNTQKAK 1043
Query: 2734 LQTRN----QELEYIV----------NDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXX 2871
+Q N Q+LE + N M+ +L R+K +R+
Sbjct: 1044 MQAENANIIQQLEDVEHQCSAITKERNAMQSQLDEMRAALEEETRARQKLQGDIRNLNSD 1103
Query: 2872 XXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXG-LTTQLLD 3048
K + + + Y+ L +L +
Sbjct: 1104 LDGLRESNEEEQEAKAELQRLLSKANNEAQQWRVKYESEGANKAEELEEARRKLQAKLQE 1163
Query: 3049 HEERAKHG-------VKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDH 3207
E+ A+ KAK RL +L +L D+ R + LE+ +R +++ +
Sbjct: 1164 AEQNAEAANAKVSSLEKAKNRLTGELEDLGIDVERANANANSLEKKQRAFDKTIQEWQAK 1223
Query: 3208 LAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDM--- 3378
+ + ++E + EL +Y+E +V ++++ +++ I EL E +
Sbjct: 1224 VTDLQSELENAQKEARSYSAELFRCKAQYEESQDSVEALRRENKNLAEEIHELTEQLSEG 1283
Query: 3379 -----ETERNARNKAEMTRREVVAQLE-----------KVKGDVLDKVDEATMLQDLMSR 3510
E E+ A+ + EM + E+ A LE KV L+ + + ++ +
Sbjct: 1284 GRSVHEVEK-AKRRLEMEKEELQAALEEAESALEQEEAKVMRGQLEISNVRSEIERRLQE 1342
Query: 3511 KDEEVNATKR----AIEQIQHTME----GKIEEQ--KAKFSRQVEELHDQIEQHKKQRSQ 3660
KDEE T+R A++ +Q ++E GK E K K + + EL ++ + +++
Sbjct: 1343 KDEEFENTRRNHQRALDSMQASLEAEAKGKAEAMRIKKKLEQDINELEIALDSSNRAKAE 1402
Query: 3661 LEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQ 3840
LEK + Q+ ++M ++I Q R ++ + + E + + E RT ++Q
Sbjct: 1403 LEKNIKRYQQQVSEMQRQIEEEQRQREEVRESYNMAERRCNMLSGEV----EELRTALEQ 1458
Query: 3841 LERSR----DELDHLN-RVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANIN 4005
ER+R +EL N RV E + + ++ A+
Sbjct: 1459 AERARKGAENELFEANDRVNELSAEVQSAQSSKRKLEGDIQAMQSDLDEMNNEVRNAD-E 1517
Query: 4006 RARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNL 4185
RAR+ D+ L DE ++E+ +QQ+E+ RK
Sbjct: 1518 RARRANDDSARLADEL--------------------------RSEQEHSQQIEKFRKSLE 1551
Query: 4186 RDVEHLQKQLEESEVAKERILQSKK---KIQQELEDSSMELENVRASHRDSEKRQKKFES 4356
V+ LQ +LEE+E + + KK K++Q + + EL++ + H +++K +K +
Sbjct: 1552 SQVKDLQVRLEEAEA--QALKGGKKMIAKLEQRVRELEGELDSEQRRHAETQKHMRKADR 1609
Query: 4357 QMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVR-------RS 4515
++ E +A Q D D +QE + + L N++ K +EE++ + R
Sbjct: 1610 RLKE--IAFQA---DEDRKNQE--NLNEMIEKLNNKLKTYKRQVEEAEEIAAINLAKYRK 1662
Query: 4516 LQQELQDSISNKDDFGKNVHELEKAKRS 4599
+QQEL+D+ D ++ +L RS
Sbjct: 1663 VQQELEDAEERADSAEGSLQKLRAKNRS 1690
Score = 109 bits (272), Expect = 9e-22
Identities = 107/454 (23%), Positives = 208/454 (45%), Gaps = 17/454 (3%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L QL E + ++ + K LE K +L A LE+++ L ++ KV ++ E
Sbjct: 1276 LTEQLSEGGRSVHEVEKAKRRLEMEKEELQAALEEAESALEQEEAKVMRGQLEISNVRSE 1335
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
++ +L DEE N R+ Q +D ++ +E E + +A ++++ + ++
Sbjct: 1336 IERRLQEKDEEFENTR------RNHQRALDSMQASLEAEAKGKAEAMRIKKKLEQDINEL 1389
Query: 3451 KGDVLDKVDEATM-LQDLMSRKDEEVNATKRAIEQIQHTME------GKIEEQKAKFSRQ 3609
+ LD + A L+ + R ++V+ +R IE+ Q E E + S +
Sbjct: 1390 E-IALDSSNRAKAELEKNIKRYQQQVSEMQRQIEEEQRQREEVRESYNMAERRCNMLSGE 1448
Query: 3610 VEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEI 3789
VEEL +EQ ++ R E + +A+ +++ E+ Q+S+ ++ + ++ L E+
Sbjct: 1449 VEELRTALEQAERARKGAENELFEANDRVNELSAEVQSAQSSKRKLEGDIQAMQSDLDEM 1508
Query: 3790 QANLAESDEHKRTLIDQLERSRDEL-------DHLNRVREEEEHAFANMQRRLATAXXXX 3948
+ +DE R D R DEL + + R+ E ++Q RL A
Sbjct: 1509 NNEVRNADERARRANDDSARLADELRSEQEHSQQIEKFRKSLESQVKDLQVRLEEAEAQA 1568
Query: 3949 XXXXXXXXXXTRLKIANIN-RARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEA 4125
+ IA + R R+LE E ++ +++ AE + H+ K ++ A +A
Sbjct: 1569 LKGG-------KKMIAKLEQRVRELEGELDS--EQRRHAE-TQKHMRKADRRLKEIAFQA 1618
Query: 4126 R--RKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMEL 4299
RK +E++N+ +E+L K ++ ++Q+EE+E L +K+QQELED+
Sbjct: 1619 DEDRKNQENLNEMIEKLNNK----LKTYKRQVEEAEEIAAINLAKYRKVQQELEDAEERA 1674
Query: 4300 ENVRASHRDSEKRQKKFESQMAEERVAVQKALLD 4401
++ S +K + K S ++ R + + LD
Sbjct: 1675 DSAEGS---LQKLRAKNRSSVSVTRTSYTTSTLD 1705
Score = 45.8 bits (107), Expect = 0.012
Identities = 56/329 (17%), Positives = 118/329 (35%), Gaps = 19/329 (5%)
Frame = +1
Query: 2506 LFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVE--RAVIQE 2679
L + K + R ++ +EL + + + + +N K+ Q + E R + +E
Sbjct: 1365 LEAEAKGKAEAMRIKKKLEQDINELEIALDSSNRAKAELEKNIKRYQQQVSEMQRQIEEE 1424
Query: 2680 QLQQESEN-------------SAELDDIRGRLQTRNQELEYIVNDM---RDRLSXXXXXX 2811
Q Q+E S E++++R L+ + + N++ DR++
Sbjct: 1425 QRQREEVRESYNMAERRCNMLSGEVEELRTALEQAERARKGAENELFEANDRVNELSAEV 1484
Query: 2812 XXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXX 2991
+RK ++ + Q+
Sbjct: 1485 QSAQSSKRKLEGDIQAMQSDLDEMNNEVRNADERARRANDDSARLADELRSEQEHSQQIE 1544
Query: 2992 XXXXXXXXXXXGLTTQLLDHEERA-KHGVKAKGRLENQLHELEQDLNRERQYKSELEQHK 3168
L +L + E +A K G K +LE ++ ELE +L+ E++ +E ++H
Sbjct: 1545 KFRKSLESQVKDLQVRLEEAEAQALKGGKKMIAKLEQRVRELEGELDSEQRRHAETQKHM 1604
Query: 3169 RKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQ 3348
RK L++ E E LN + K + +L+ + +E + + R +Q
Sbjct: 1605 RKADRRLKEIAFQADEDRKNQENLNEMIEKLNNKLKTYKRQVEEAEEIAAINLAKYRKVQ 1664
Query: 3349 TTIDELREDMETERNARNKAEMTRREVVA 3435
+++ E ++ + K R V+
Sbjct: 1665 QELEDAEERADSAEGSLQKLRAKNRSSVS 1693
>gi|32408499|ref|XP_324731.1| hypothetical protein [Neurospora crassa]
gi|28926504|gb|EAA35476.1| hypothetical protein [Neurospora crassa]
Length = 2397
Score = 915 bits (2366), Expect = 0.0
Identities = 640/1990 (32%), Positives = 994/1990 (49%), Gaps = 111/1990 (5%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
+K W+ D F+ G + E + L+ D Q + + V K NP KFDK DM+E
Sbjct: 118 KKYVWLKDPQAAFVKGWVVEELPENKLLVQCDDGSQREVDAETVDKVNPAKFDKANDMAE 177
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LT+LNEASV+HNL RY S LIYTYSGLF V +NPY LPIY+ + I +KG+ R + P
Sbjct: 178 LTHLNEASVVHNLHTRYQSDLIYTYSGLFLVAVNPYCPLPIYTNEYINMYKGRNREDNKP 237
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIFA+AD A+R+++ E E+QSIL TGESGAGKTENTKKVIQYLA VA + +
Sbjct: 238 HIFAMADEAFRNLVDEHENQSILVTGESGAGKTENTKKVIQYLAAVAHPDPSGRTRGSQH 297
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
N L Q+L+ANPILEAFGN++TV+N+NSSRFGKFIRI F +G I+G
Sbjct: 298 SN-------------LSAQILRANPILEAFGNAQTVRNNNSSRFGKFIRIEFSSNGSIAG 344
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRFLVNRG--IT 969
A I++YLLEKSRV+ +ER++HIFYQ+L+G K K E LL+ +D F R T
Sbjct: 345 AFIDWYLLEKSRVVHVNANERNYHIFYQLLKGADRKLKQELLLDSMDVKDFTYTRDGHDT 404
Query: 970 LPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKS-DQAMLQDD 1146
+ V D +E+ S I + +MGF+D+E +I+R ++AVL LGN+ +E +S DQA L D
Sbjct: 405 ITGVSDKEEWDSLIEAFLVMGFSDEEQVAILRTIAAVLHLGNITVVKESRSADQARLNPD 464
Query: 1147 --RVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLF 1320
+ + C LLG+P+ + L PR+K GRE+V K Q EQ A++A+AK YER F
Sbjct: 465 AKAIAGRACKLLGVPLEPFLQGLLHPRVKAGREWVEKVQTPEQVRLAIDALAKGIYERGF 524
Query: 1321 KWLVTRINKSLDRTHR--QGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTM 1494
LV RIN+ LDRT FIG+LDIAGFEIF+ NSFEQ+CINYTNEKLQQ FN+ M
Sbjct: 525 GDLVARINRQLDRTSMGLDDTRFIGVLDIAGFEIFETNSFEQLCINYTNEKLQQFFNHHM 584
Query: 1495 FILEQEEYQREGIEWDFIDFGLDLQPTIDLIE--KPMGVLALLDEECLFPKANDKSFVEK 1668
F+LEQEEY RE IEW FIDFG DLQPTIDLIE P+G+ + LDE+C+ PKA DK+F EK
Sbjct: 585 FVLEQEEYAREQIEWKFIDFGRDLQPTIDLIELPNPIGIFSCLDEDCVMPKATDKTFTEK 644
Query: 1669 LQKTHNKHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDP 1848
L +K + P R F + HYA V+YS + WL KN DPLN+N+ L+ STD
Sbjct: 645 LNSLWDKKSQKYRPS-RLGQGFILTHYAAEVEYSTEGWLEKNKDPLNDNITRLLAASTDK 703
Query: 1849 FVAGIWKDAEFAGICAAEMNETAFGMRSR--KGMFRTVSQLHKEQLTKLMTTLRNTSPHF 2022
++A ++ D A+ ++ A MRSR KG+FRTV+Q HKEQL+ LMT L +T PHF
Sbjct: 704 YMANLFSD-------CADQDDEAGAMRSRVKKGLFRTVAQRHKEQLSSLMTQLYSTHPHF 756
Query: 2023 VRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDV 2202
VRCIIPNH+KK + S LVL+QLRCNGVLEGIRI R GFPNR+PF EFR RYE+L P+
Sbjct: 757 VRCIIPNHKKKPKQFQSLLVLDQLRCNGVLEGIRIARTGFPNRLPFAEFRQRYEVLCPN- 815
Query: 2203 IPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQA 2382
+PK +++G+ + R M+ +D +LYR+G +KVFFR GVLA LEE+RD +T ++ FQ+
Sbjct: 816 MPKGYVEGQAAARIMLDRFGLDKSLYRVGLTKVFFRAGVLAELEEKRDAIITEIMAKFQS 875
Query: 2383 QCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIR 2562
RG++ RR+ N YL+L WW+L ++KPLL TRT E++
Sbjct: 876 LARGYIKRRIAYKRLYRAEATRVIQRNFQVYLELSENPWWQLMVRMKPLLGATRTATEVK 935
Query: 2563 AKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQT 2742
+D+ +R +R+ + D + E++ V E IQ+ L+ E + + ++I RLQ
Sbjct: 936 KRDEMIRQLSDRMKQEAMDRQRLEEERRNVHAEMLRIQQTLESERALALDKEEIFKRLQL 995
Query: 2743 RNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTN 2922
R ELE D+L+ +++ME D +T
Sbjct: 996 REAELE-------DKLAGALDD--------QERMEEQMDGLLEAKKRAEVDVEKY--RTQ 1038
Query: 2923 VDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQ 3102
++Q + L Q+++ ++ + + LEN+
Sbjct: 1039 LEQAATIIGRLEDEKSE-----------LANRIADLERQIVEISQKQSERSEQETALENE 1087
Query: 3103 LHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHL---AEKMGKVEELNNQLMKRDEEL 3273
L L+ L+ + + +LE KLL +DS L +++ + N QL + +
Sbjct: 1088 LKMLQSQLSLKDRKVKDLES---KLLKIDQDSDVKLLATEKELQIAKSKNEQLTTENTQF 1144
Query: 3274 QHQLTRYDEES-----------ANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTR 3420
Q QLT+ + S + + +++ + + + T + + + + R KA
Sbjct: 1145 QQQLTQLSKTSTSYEDLIRKKESELAILRSENKQLATERRSIDDQTKMLASEREKAAERL 1204
Query: 3421 REVVAQLEKVK---GDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQK 3591
REV A+L +K ++ + ++A L +D + + ++ +E ++ ++ +
Sbjct: 1205 REVQAELTAMKSQQAQLMREAEDAKKLLQARLSEDAQADQNRQVLEAQIKDLKDELYNAQ 1264
Query: 3592 AKFSRQ--------------VEELHDQIEQHKKQRSQLEKQ--------------QNQAD 3687
+ SR+ + L D+ + + +EK+ + +
Sbjct: 1265 MELSRERQSRDDVQLLGEHKYQTLKDEYNHLNESKITIEKELYAQQDTLRRAVETRTTLE 1324
Query: 3688 QERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELD 3867
QER D +EI L+++ ++ R+ EA ++ +A + E + +L+ L+ + D+L
Sbjct: 1325 QERDDAREEIRRLRSAMTQAEEARR--EAEVLGERAATKIAREREESLLKDLDAANDKLK 1382
Query: 3868 HLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLD 4047
+ + ++ + + + R +R E++ ALL+
Sbjct: 1383 WYESECAKLNYQVEDLNKVIIESGEFGLKNDQAKERLERELNTVRSRLAASENDNRALLN 1442
Query: 4048 EKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESE 4227
K + +GL EI + AGEA R V ++ + ++N + L KQL +S+
Sbjct: 1443 -KLQQKGL------EIARSASRAGEASRAQLVQVQREKTRVEEQNTK----LNKQLGDSQ 1491
Query: 4228 VAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDR- 4404
V + + +K+Q +ED + EL + R++EK Q+AE ++ R
Sbjct: 1492 VTVAGLEKKVEKLQLTIEDLNHELARETQASRNAEKLSSNVTVQLAEANRTIESERQLRT 1551
Query: 4405 -------------DAMSQELRDRETRVLSLLNEVDIMKE----HLEESDRVRRSLQQELQ 4533
DA +EL + ++LS L VD + E + R L +
Sbjct: 1552 QAQGTVRTLQSTLDARDKELIELRAQLLSALKTVDPDTDDTHVQTEGASASERFLSKNF- 1610
Query: 4534 DSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQAL-- 4707
D + +D +N+ A+ S EA+L D+R + ++ E + T
Sbjct: 1611 DLVRKIEDLQQNLRVQTTARASAEAQLADLRTSRNDSPTRPRLEEISPNEAPFTGSPTQK 1670
Query: 4708 KSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQ 4887
+ + R SN E RR +L + + +++ + + R + +I EL+ Q
Sbjct: 1671 RKTNGRHHSNASTSPRE-RRFTNSDSENLHDSVRSDRTADIVSFNTRMDFKAEIEELQNQ 1729
Query: 4888 LEVANRLKEEYXXXXXXXXXXXXEYQIE-------CEEARQAKEDIAALLREADRKFRAV 5046
L++A + ++ ++ +A + LL ++ +K A+
Sbjct: 1730 LQLAQMQNRHLQSQLERTASGEEDAYLDESPQLRRVQKLEKANNRLHELLDDSSKKVSAL 1789
Query: 5047 EAERE---------QLREANEGLMQARKQXXXXXXXXXXXRAKGGGISS-----EEKRRL 5184
E Q R E L Q + ++ ++ R
Sbjct: 1790 EKALRTGELSLRDIQTRSHEEILDLLNSQEDSRRSLLHSHKDAVAELTELKEHYDKVRHE 1849
Query: 5185 EAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLS--MERTLNQKTEAEKQSLE- 5355
AK+ LA D++ ++ QL Q DL ++ ++ +AE L+
Sbjct: 1850 RAKLEVDLRDARSDLQEMSLARDQEAASRSQLLQEFADLQIRLDAEASKLADAEIAVLKA 1909
Query: 5356 -RSNRDYKAKITELESGA------QSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAA 5514
R+ +A+ E E + R + L+ Q LE+++ + A +A
Sbjct: 1910 NRAEAFARAQAKEAEDSCAEMMSERKRLDTMIEDLQHSNQRLEEKIEDMSTDLAAVTQAK 1969
Query: 5515 RRLEKRLNDTTQQ----FEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKH 5682
+RL+ L D Q ED++ + EQ + +K + L +LD A +E R++++
Sbjct: 1970 KRLQHELEDYRNQRANDIEDKESSMEQMR---KKYQAEFATLANELDRAREEKLRKQSEI 2026
Query: 5683 RNVQREADDL 5712
++ E D+L
Sbjct: 2027 TRLREELDEL 2036
Score = 147 bits (372), Expect = 2e-33
Identities = 184/906 (20%), Positives = 366/906 (40%), Gaps = 39/906 (4%)
Frame = +1
Query: 3145 KSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLM 3324
K+ +E+ KL +L DS+ +A KVE+L + E+L H+L R + S N
Sbjct: 1473 KTRVEEQNTKLNKQLGDSQVTVAGLEKKVEKLQLTI----EDLNHELARETQASRNA--- 1525
Query: 3325 QKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLM 3504
+K ++ + E +E+ER R +A+ T R + + L D DK Q L
Sbjct: 1526 EKLSSNVTVQLAEANRTIESERQLRTQAQGTVRTLQSTL-----DARDKELIELRAQLLS 1580
Query: 3505 SRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQA 3684
+ K + + ++ + + + R++E+L + R+ E Q
Sbjct: 1581 ALKTVDPDTDDTHVQTEGASASERFLSKNFDLVRKIEDLQQNLRVQTTARASAEAQLADL 1640
Query: 3685 DQERADMAQEIALLQASRADID------KKRKIHEAHLMEIQANLAE---SDEHKRTLID 3837
R D L + S + +KRK + H + E ++ L D
Sbjct: 1641 RTSRNDSPTRPRLEEISPNEAPFTGSPTQKRKTNGRHHSNASTSPRERRFTNSDSENLHD 1700
Query: 3838 QLERSRD--------ELDHLNRVRE-EEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLK 3990
+ R +D + E + + A MQ R + +
Sbjct: 1701 SVRSDRTADIVSFNTRMDFKAEIEELQNQLQLAQMQNRHLQSQLERTASGEEDAYLD--E 1758
Query: 3991 IANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQL--- 4161
+ R ++LE N L + +++ + LEK + + + ++ E + L
Sbjct: 1759 SPQLRRVQKLEKANNRLHELLDDSSKKVSALEKALRTGELSLRDIQTRSHEEILDLLNSQ 1818
Query: 4162 EELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVR-ASHRDSEKR 4338
E+ R+ L + +L E + +++ + K++ +L D+ +L+ + A +++ R
Sbjct: 1819 EDSRRSLLHSHKDAVAELTELKEHYDKVRHERAKLEVDLRDARSDLQEMSLARDQEAASR 1878
Query: 4339 QKKFE-------------SQMAEERVAVQKALLDRD---AMSQELRDRETRVLSLLNEVD 4470
+ + S++A+ +AV KA A ++E D ++S +D
Sbjct: 1879 SQLLQEFADLQIRLDAEASKLADAEIAVLKANRAEAFARAQAKEAEDSCAEMMSERKRLD 1938
Query: 4471 IMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQM-EELE 4647
M E L+ S+ Q L++ I +D ++ + +AK+ L+ EL D R Q ++E
Sbjct: 1939 TMIEDLQHSN-------QRLEEKI---EDMSTDLAAVTQAKKRLQHELEDYRNQRANDIE 1988
Query: 4648 DNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGK 4827
D E R + + L +E DRA K + E R L +++ +L ++ ++E
Sbjct: 1989 DKESSMEQMRKKYQAEFATLANELDRAREEKLRKQSEITR-LREELDELRSKWDDEVLNS 2047
Query: 4828 SGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIA 5007
S + ++E + ++ VA+R +E + R + ++I
Sbjct: 2048 STWSKEKARLEATLSDV-----VASR--DEAVSAHNEAQSKIVTLLGQVRSLRSSLDEIT 2100
Query: 5008 ALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLE 5187
A E D FR + +L EA GL + A S ++
Sbjct: 2101 A---ERDALFREKRSIEARLEEAKAGLDEL---------------ANSESPSLRNAAHMD 2142
Query: 5188 AKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNR 5367
+I + + A++K R+A+ ++ D++ ER N + +K +LE++
Sbjct: 2143 REILELKSSLAQQEDIAAAAVEKMRRAEALAAEVQKDIAAERENNADLQKQKVTLEKNFN 2202
Query: 5368 DYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTT 5547
+ + K+ +LE+ S A + L ++++ LE QL + E++ + R+ R +++ + D
Sbjct: 2203 ELQMKLIDLETKGYSTASHDIKFLHSRIKELESQLEEQENERSKSQRSVRNVDRIVKDLQ 2262
Query: 5548 QQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANE 5727
Q + + + N Q +E + + K L + +DE + S R +RE + +
Sbjct: 2263 SQIDRKDKQNTQLQEDVTRMRDKVDKLLKTIDELQSSESANELSARRAERELREEKEKAL 2322
Query: 5728 QLTREL 5745
+L REL
Sbjct: 2323 RLEREL 2328
Score = 100 bits (248), Expect = 6e-19
Identities = 194/994 (19%), Positives = 375/994 (37%), Gaps = 135/994 (13%)
Frame = +1
Query: 3175 LLAELEDSKDHL-AEKMGKVEELNNQLMKR------------DEELQHQLTRYDEESAN- 3312
+LAELE+ +D + E M K + L +KR +Q Y E S N
Sbjct: 854 VLAELEEKRDAIITEIMAKFQSLARGYIKRRIAYKRLYRAEATRVIQRNFQVYLELSENP 913
Query: 3313 -------------VTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQ----- 3438
T +++ I +L + M+ E R + E RR V A+
Sbjct: 914 WWQLMVRMKPLLGATRTATEVKKRDEMIRQLSDRMKQEAMDRQRLEEERRNVHAEMLRIQ 973
Query: 3439 --LEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQV 3612
LE + LDK + LQ + ++++ E+++ M+G +E +K + V
Sbjct: 974 QTLESERALALDKEEIFKRLQLREAELEDKLAGALDDQERMEEQMDGLLEAKK-RAEVDV 1032
Query: 3613 EELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQ 3792
E+ Q+EQ +LE ++++ AD+ ++I + +++ ++ E L +Q
Sbjct: 1033 EKYRTQLEQAATIIGRLEDEKSELANRIADLERQIVEISQKQSERSEQETALENELKMLQ 1092
Query: 3793 ANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXX 3972
+ L+ D + L +L + + D + + E+E A + T
Sbjct: 1093 SQLSLKDRKVKDLESKLLKIDQDSD-VKLLATEKELQIAKSKNEQLTTENTQFQQQLTQL 1151
Query: 3973 XXTRLKIANINR-------------------ARQLEDEKNALLDEKEEAEGLRAHLEKEI 4095
T ++ R R ++D+ L E+E+A ++ E+
Sbjct: 1152 SKTSTSYEDLIRKKESELAILRSENKQLATERRSIDDQTKMLASEREKAAERLREVQAEL 1211
Query: 4096 HAARQGAGEARRKAEES---------------VNQQLEELRKKNLRD--------VEHLQ 4206
A + + R+AE++ N+Q+ E + K+L+D + +
Sbjct: 1212 TAMKSQQAQLMREAEDAKKLLQARLSEDAQADQNRQVLEAQIKDLKDELYNAQMELSRER 1271
Query: 4207 KQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQ 4386
+ ++ ++ E Q+ K L +S + +E + +D+ +R + + + +ER +
Sbjct: 1272 QSRDDVQLLGEHKYQTLKDEYNHLNESKITIEKELYAQQDTLRRAVETRTTLEQERDDAR 1331
Query: 4387 KALLD-RDAMSQ-ELRDRETRVL--------------SLLNEVDIMKEHLE--ESDRVRR 4512
+ + R AM+Q E RE VL SLL ++D + L+ ES+ +
Sbjct: 1332 EEIRRLRSAMTQAEEARREAEVLGERAATKIAREREESLLKDLDAANDKLKWYESECAKL 1391
Query: 4513 SLQ-QELQDSISNKDDFG-KNVHELEKAKRSLEAELNDMRVQMEELE-DNLQIAEDARLR 4683
+ Q ++L I +FG KN ++AK LE ELN +R ++ E DN + + +
Sbjct: 1392 NYQVEDLNKVIIESGEFGLKN----DQAKERLERELNTVRSRLAASENDNRALLNKLQQK 1447
Query: 4684 -LEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIE 4860
LE+ A S + A + V+ + ++ + +Q L +L + + +G +K++
Sbjct: 1448 GLEIARSA--SRAGEASRAQLVQVQREKTRVEEQNTKLNKQLGDSQVTVAGLEKKVEKLQ 1505
Query: 4861 NQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFR 5040
I +L +L + E E RQ + +R
Sbjct: 1506 LTIEDLNHELARETQASRNAEKLSSNVTVQLAEANRTIESERQLRTQAQGTVRTLQ---S 1562
Query: 5041 AVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXX 5220
++A ++L E L+ A K + G S+ E R +K
Sbjct: 1563 TLDARDKELIELRAQLLSALK---TVDPDTDDTHVQTEGASASE--RFLSKNFDLVRKIE 1617
Query: 5221 XXQSNCELAIDKQRKAQVQLEQITTDL-----------------------SMERTLNQKT 5331
Q N + + A+ QL + T + +R N +
Sbjct: 1618 DLQQNLRVQTTARASAEAQLADLRTSRNDSPTRPRLEEISPNEAPFTGSPTQKRKTNGRH 1677
Query: 5332 EAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRA 5511
+ + R R + L +S A + + ++ + + ++ Q + A
Sbjct: 1678 HSNASTSPRERRFTNSDSENLHDSVRSDRTADIVSFNTRMDFKAEIEELQNQLQ-LAQMQ 1736
Query: 5512 ARRLEKRLNDTTQQFEDE--------------KRANEQAKELLEKSNLKNRNLRRQLDEA 5649
R L+ +L T ED ++AN + ELL+ S+ K L + L
Sbjct: 1737 NRHLQSQLERTASGEEDAYLDESPQLRRVQKLEKANNRLHELLDDSSKKVSALEKALRTG 1796
Query: 5650 EDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
E + +T+ E DLL++ E R L++
Sbjct: 1797 ELSLRDIQTRS---HEEILDLLNSQEDSRRSLLH 1827
Score = 90.9 bits (224), Expect = 3e-16
Identities = 114/544 (20%), Positives = 237/544 (42%), Gaps = 47/544 (8%)
Frame = +1
Query: 3052 EERAKHGVKAKGRLENQLHELEQDL--NRERQYKSELEQHKRKLLAELEDSKDHLAEKMG 3225
E+ + G + ++ + HE DL ++E +S L HK +AEL + K+H +
Sbjct: 1790 EKALRTGELSLRDIQTRSHEEILDLLNSQEDSRRSLLHSHK-DAVAELTELKEHYDKVRH 1848
Query: 3226 KVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNK 3405
+ +L L +LQ D+E+A+ + + ++ D+Q +D + A K
Sbjct: 1849 ERAKLEVDLRDARSDLQEMSLARDQEAASRSQLLQEFADLQIRLDAEASKLADAEIAVLK 1908
Query: 3406 AEMTRREVVAQLEKVKGDVLDKVDEA----TMLQDL------MSRKDEEVNATKRAIEQI 3555
A AQ ++ + + + E TM++DL + K E+++ A+ Q
Sbjct: 1909 ANRAEAFARAQAKEAEDSCAEMMSERKRLDTMIEDLQHSNQRLEEKIEDMSTDLAAVTQA 1968
Query: 3556 QHTMEGKIEEQKAKFSRQVEELHDQIEQ-HKKQRSQLEKQQNQADQERADMAQEIALLQA 3732
+ ++ ++E+ + + + +E+ +EQ KK +++ N+ D+ R + ++ + +
Sbjct: 1969 KKRLQHELEDYRNQRANDIEDKESSMEQMRKKYQAEFATLANELDRAREEKLRKQSEITR 2028
Query: 3733 SRADID-----------------KKRKIHEAHLMEIQANLAES-DEHKR------TLIDQ 3840
R ++D K++ EA L ++ A+ E+ H TL+ Q
Sbjct: 2029 LREELDELRSKWDDEVLNSSTWSKEKARLEATLSDVVASRDEAVSAHNEAQSKIVTLLGQ 2088
Query: 3841 LERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINR---- 4008
+ R LD + R+ +++ RL A R A+++R
Sbjct: 2089 VRSLRSSLDEITAERDALFREKRSIEARLEEAKAGLDELANSESPSLR-NAAHMDREILE 2147
Query: 4009 ----ARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRK 4176
Q ED A +++ AE L A ++K+I A R+ + +K + ++ + EL+
Sbjct: 2148 LKSSLAQQEDIAAAAVEKMRRAEALAAEVQKDIAAERENNADL-QKQKVTLEKNFNELQM 2206
Query: 4177 KNLRDVEHLQKQLEESEVAKERILQSK-KKIQQELEDSSMELENVRASHRDSEKRQKKFE 4353
K L D+E ++ + L S+ K+++ +LE+ E + S R+ ++ K +
Sbjct: 2207 K-LIDLETKGYSTASHDI---KFLHSRIKELESQLEEQENERSKSQRSVRNVDRIVKDLQ 2262
Query: 4354 SQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLE-ESDRVRRSLQQEL 4530
SQ+ +R Q L D +RD+ ++L ++E+ + E + R R L++E
Sbjct: 2263 SQI--DRKDKQNTQLQEDV--TRMRDKVDKLLKTIDELQSSESANELSARRAERELREEK 2318
Query: 4531 QDSI 4542
+ ++
Sbjct: 2319 EKAL 2322
>gi|50555922|ref|XP_505369.1| hypothetical protein [Yarrowia
lipolytica]
gi|49651239|emb|CAG78176.1| unnamed protein product [Yarrowia
lipolytica CLIB99]
Length = 2084
Score = 902 bits (2331), Expect = 0.0
Identities = 640/2071 (30%), Positives = 1032/2071 (48%), Gaps = 174/2071 (8%)
Frame = +1
Query: 61 AAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKI 240
A +A +K WV D GF+ G + E D V D +R V I+ D K NPPKF+
Sbjct: 41 AEFAAKKWVWVADPTVGFIKGFVVSEEGDNYTVNCGDENRVVKIN--DTDKVNPPKFNMA 98
Query: 241 EDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKR 420
DM+ELT+L+EA+V+ NL RY S +IYTYSGLF V INPY+ LPIY +D I ++ K R
Sbjct: 99 SDMAELTFLSEAAVIANLASRYKSDMIYTYSGLFLVAINPYRSLPIYDKDTIRSYRNKHR 158
Query: 421 HEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSL 600
E+PPHIFAI D A+++M++ E+QSIL TGESGAGKTENTKKVIQYLA VA ++ S
Sbjct: 159 DEVPPHIFAITDLAFQNMMEAHENQSILVTGESGAGKTENTKKVIQYLAAVAQEGKHASA 218
Query: 601 NAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMS 780
+ E ++LQANPILEAFGN++TV+N+NSSRFGKFIRI F+ +
Sbjct: 219 DDCT----------------FEDKILQANPILEAFGNAQTVRNNNSSRFGKFIRIEFERA 262
Query: 781 GYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDN---YRFL 951
G I+GA I++YLLEKSRV+ Q ER++H+FYQ+L G SA+ + + L++ N + +L
Sbjct: 263 GAIAGAVIDWYLLEKSRVISQNSRERNYHVFYQLLSGASAELREQLLIKDSVNPADHSYL 322
Query: 952 VNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEF----TQEKK 1119
+P V+D EF S +IMGF D E SI + +SA+L LGN+E T+
Sbjct: 323 KGSNYEIPGVNDKAEFGVLQKSFQIMGFTDKEQHSIFQTLSAILHLGNIELAGEGTRGSG 382
Query: 1120 SDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAK 1299
+QA L D +++CHLLG+ + L P++K GRE+V + ++ EQ F+++++AK
Sbjct: 383 VNQARLVDISQAERLCHLLGISTQQFVTCLLHPKVKAGREWVQQNRSTEQVRFSLDSLAK 442
Query: 1300 ASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQL 1479
+ YER F ++V RIN L ++ FIG+LDIAGFEIF +NSFEQ+CINYTNE+LQQ
Sbjct: 443 SLYERTFGFIVDRINTCL-QSGASDTQFIGVLDIAGFEIFQVNSFEQLCINYTNERLQQF 501
Query: 1480 FNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEK--PMGVLALLDEECLFPKANDK 1653
FN+ MF+LEQEEY RE IEW ++DFG DLQPTIDLIEK P+G+ + LDE+C+ PKA+DK
Sbjct: 502 FNHHMFVLEQEEYARENIEWKYVDFGHDLQPTIDLIEKPNPIGIFSCLDEDCVMPKASDK 561
Query: 1654 SFVEKL-QKTHNKHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLM 1830
+F EKL Q K PK+ R K F + HYA V+YS + WL KN DPLN NV+ L+
Sbjct: 562 TFTEKLHQLWDKKSPKY--KSSRLKQGFVLTHYAADVEYSTEGWLDKNKDPLNANVIELL 619
Query: 1831 QNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNT 2010
S+D + ++++ A +A G +KG+FRTV+Q HKEQL LMT L+ T
Sbjct: 620 VESSDSHIRCLFQEE----AKEAARETSARGKGGKKGIFRTVAQKHKEQLNSLMTRLQAT 675
Query: 2011 SPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEIL 2190
PHFVRCIIPNH+K+ ++S LVL+QLRCNGVLEGIRI R GFPNR+PF +F+ RY++L
Sbjct: 676 HPHFVRCIIPNHKKQPQSLDSLLVLDQLRCNGVLEGIRIARSGFPNRLPFSDFKSRYQVL 735
Query: 2191 TPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIM 2370
P +P+ F+DG+++ + +++ L +DTNLYR+G +KVFF++GVLA LEE+R+ + +I+
Sbjct: 736 VP--MPQGFMDGQKACQHILSGLKMDTNLYRVGLTKVFFKSGVLAELEEQRESCVRDVIV 793
Query: 2371 NFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTD 2550
FQ+ RG ++RR + N Y L++ +WW+L+ K++PLL ++
Sbjct: 794 RFQSLARGCMTRRKFLKAQHRHEAALIIKKNLSVYRHLKDNKWWKLYVKMRPLLATSKDI 853
Query: 2551 DEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRG 2730
E RAKD E++ ++++ + +++ + E A I+E+L E +A+ D+I
Sbjct: 854 VERRAKDAEVKRLEKKMADIVETRDSLDERCRKAETELAKIEEKLTSERATAADKDEILR 913
Query: 2731 RLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXX 2910
R Q + EL + + + L +++ E
Sbjct: 914 RSQEKEAELSAQLEEAYEDLDQLETQMEELLAAKKRADEQTDTLKKELDNGAKLLSKLES 973
Query: 2911 DKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGR 3090
+KT++ + + + + E + + + + R
Sbjct: 974 EKTDLATSMASIEKELAEATEKHSNRLTESESLNEQLSMIRNCVAMREAKIE---ELESR 1030
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLA---------EKMGKVEELN 3243
LE EL L + R+L+ E ++ +D LA EK+ + +E
Sbjct: 1031 LEESEKELGSRLAAATSGFDSANRRIRELIRENKEVRDQLADLHATSFGYEKLVRKKEQE 1090
Query: 3244 NQLMKRD--------EELQHQL----TRYDEESANVTLMQKQMRDMQTTIDELREDMETE 3387
++K D E++ Q T+++ SA + ++++ + ++L++++ET
Sbjct: 1091 QAVLKADLDRHVKDLEDISRQKQSLETKHESVSAELAAANEEIKTLSANHEQLKQELETR 1150
Query: 3388 RNARNKAEMTR-REVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHT 3564
R E + +++ + E +K ++ + T+ + S+ EV+ K +
Sbjct: 1151 RQESESEEKQKAAQMMLETEALKEELAKERRRRTVAESEASKTQNEVSRVKSELSAKSSE 1210
Query: 3565 MEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEK------------QQNQADQERADMA 3708
+EG +++ K ++V+ L Q+E+ + +S E+ Q A R D +
Sbjct: 1211 VEG-LQKSKQSADKEVKRLQSQVEKAQAAQSAAERALSKVEADLKVAQDEAAHLTRQDKS 1269
Query: 3709 QEIAL---LQASRADIDKKRKIHEAHLME---IQANLAESDEHKRTLI------------ 3834
+E++L +++ R + K R ++EA + + L K+ L
Sbjct: 1270 RELSLKSQVESLRNESAKHRTLNEALTADAGSFKTRLDALATEKKALTSQIATLTSASGA 1329
Query: 3835 --DQLERSRDELD----HLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL--K 3990
DQL R+ +D L ++R + E A Q RLA L K
Sbjct: 1330 DKDQLAVLREAIDVKNNQLTKLRSQVE---AETQARLAHVSQSSQEKQQSDDHVASLKRK 1386
Query: 3991 IANI------------NRARQLE--------DEKNALLDEKEEAEGLRAHLEKEIHAARQ 4110
++ + AR++E D K+AL E+ E L+A LEKE R
Sbjct: 1387 LSELETVYSTGEKQRERMAREIEDLKHHNTQDHKSALSQERLVTE-LKAALEKE-RRERS 1444
Query: 4111 GAGEARRKAEESVNQQLE--ELRKKNL---------------RDVEHLQK---------- 4209
RRK + V+ E ELR + D E L+K
Sbjct: 1445 ETAVLRRKLQSQVDSLTETVELRTSQVTALNRAVLGPNKPLPSDPESLEKAISSTVDLAT 1504
Query: 4210 QLEESEVAKERILQSKKKIQQELEDS-----SMELENV--RASHRDSEKRQKKFESQMAE 4368
+LEESE + + LQ K++ +E S S + +N+ R SH D S+
Sbjct: 1505 RLEESE-RRCKALQDGKQLAEEQFRSAKQRWSADTDNLSSRRSHEDINLTSYTSPSKTKR 1563
Query: 4369 ERVAVQKALLDRDA------MSQELRDRETRVLSLLNEVDIMKEHLEE-------SDRVR 4509
+ L+RD+ + ++L E + L + ++ + EE S R
Sbjct: 1564 PLSVSAVSHLNRDSNGMDAKLKEKLAAAELALSQALAKNKLLAKEAEEARSRSHVSARDM 1623
Query: 4510 RSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLE 4689
+ + SIS+K D + R L+ +L R + EE ++ AE A L+
Sbjct: 1624 SPERPSSKASISSKPDMNFQLEAERSRNRDLQEDLQLYRQRAEEYYGKIESAEIAILKSS 1683
Query: 4690 VTNQALKSESDRAISNKDVEAEEKRRG------LLKQIRDLENELENEKRGKSGAVSHRK 4851
+ K A S + E+++ L ++R LEN+LE+++ + K
Sbjct: 1684 RAEEFAKQRCQEAESERSQLLAERQKAETALIELQAEVRGLENQLEDKEMEVATLRRSHK 1743
Query: 4852 KIENQIGE---------------LEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEAR 4986
++E + G L + + + L+++ + ++E EA+
Sbjct: 1744 RLETEQGRGLEGSKSELAELTKTLAAETKNVSSLRQQNMMLQQQTDAMKRQRELEQSEAK 1803
Query: 4987 QAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISS 5166
Q ++ E DR V ++Q + + +A+K+ R I++
Sbjct: 1804 QWRD-------EHDRLAAQVHDLQQQAQADEKANSEAQKRVASLLSQVQNLRTTMDEIAT 1856
Query: 5167 E------EKRRLEAKIA----------QXXXXXXXXQSNCELAIDKQRKAQVQLEQITTD 5298
+ +KR LE++++ + +++ +++ + R A+
Sbjct: 1857 DRDQLLKDKRALESRVSTMAVDLESLLKSHGETPLSRTSSQVSSTQLRTAEKSAADALAA 1916
Query: 5299 LSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNV 5478
L ER + Q +K+ E+ ++ KI +LES S AL +V LE +L
Sbjct: 1917 LERERRVMQ---TQKRESEQQTKELNLKILDLESRLLSSGGGDTEALRKRVSQLEKELQQ 1973
Query: 5479 EGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDE 5658
+ + A +++R +++ + Q + + ++ +E KS K L +++A+
Sbjct: 1974 QQSDMLADLKSSRGGDRQARELRDQLDQRDQLVKRLQEESAKSEAKVNRLVEAVEKAQGS 2033
Query: 5659 MSRERTKHRNVQREADDLLDANEQLTRELMN 5751
S+ + R +RE+ +L + + +L ++L N
Sbjct: 2034 ESQYQVVARRAERESRELREKSLRLEKDLEN 2064
>gi|34869316|ref|XP_221489.2| similar to myosin heavy chain [Rattus
norvegicus]
Length = 2001
Score = 901 bits (2328), Expect = 0.0
Identities = 596/1974 (30%), Positives = 987/1974 (49%), Gaps = 86/1974 (4%)
Frame = +1
Query: 64 AWAQRKLCWVPDQNEGFLIGSIKRETND-EVLVELVDTSRQVTISRDDVQKANPPKFDKI 240
A+ +K CWVPD + +K + D V+VE D + I D++Q+ NP + + I
Sbjct: 26 AFDGKKKCWVPDGKNAYTEAEVKESSGDGHVIVETRD-GESLRIREDEIQQMNPAELEMI 84
Query: 241 EDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKR 420
ED+S L Y+NE SVLH L+ RY +IYTYSGLFCV INPYK LP+Y ++++ +K K+R
Sbjct: 85 EDLSMLLYINEGSVLHTLRKRYDHWMIYTYSGLFCVAINPYKWLPVYQKEVMAAYKRKRR 144
Query: 421 HEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSL 600
E PPHIFA+A+ A++ ML+ E+QSIL TGESG+GKT NTK +IQY A +A + K
Sbjct: 145 SEAPPHIFAVANHAFQDMLRNGENQSILFTGESGSGKTVNTKMIIQYFATMAATSEPKK- 203
Query: 601 NAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMS 780
+G LE Q++Q NPILEAFGN+KT++NDNSSRFGKFIR+ F +
Sbjct: 204 ----------------KLGNLEDQIVQMNPILEAFGNAKTLRNDNSSRFGKFIRMYFGVR 247
Query: 781 GYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRFLVNR 960
G +S A+I+ Y LEKSRV+ Q ER++HIFYQIL G + + ++
Sbjct: 248 GTLSFADIQIYFLEKSRVVYQQPGERNYHIFYQILSGKQELQDMLLVSTNPSDFHICSCG 307
Query: 961 GITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQ 1140
+ + N+DD + F +T ++ ++GF DE ++V A++ GNL+F Q + +Q
Sbjct: 308 VVAVENLDDAKGFLATEKAIDVLGFLPDEKFGCYKLVGAIMHFGNLKFRQNPREEQLEAD 367
Query: 1141 DDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQ----------------- 1269
K L+G+ EL K + PRIKVG E+V ++QN +Q
Sbjct: 368 GTENADKAALLMGINASELLKGLIYPRIKVGNEYVTRSQNIQQEGENQTENENNKELEVK 427
Query: 1270 ----------------AEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDI 1401
+AV A++K+ YER+FKWLV R+N+ LD FIGILDI
Sbjct: 428 ISQSLQEHYWDGTSGKVTYAVGALSKSIYERMFKWLVARMNQVLD-AKVTSHFFIGILDI 486
Query: 1402 AGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTID 1581
GFEI D NS EQ+CIN+TNEKLQQ FN +F+LEQEE ++EG++W ID+GLDLQ ID
Sbjct: 487 TGFEILDYNSLEQLCINFTNEKLQQFFNQQLFVLEQEECRKEGLDWMSIDYGLDLQACID 546
Query: 1582 LIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPKF---IVPDMRSKSHFAVVHY 1749
LIEKPMG+L++L+EEC+ PKA D +F KL H K F P+ + HF + HY
Sbjct: 547 LIEKPMGILSILEEECMLPKATDNTFKTKLFAHHFGKSAYFQKPTAPEKNFEVHFELAHY 606
Query: 1750 AGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMR 1929
AG V Y W+ KN + LNE VV L+Q S++ +A ++ + AG + TA +
Sbjct: 607 AGVVPYDISGWIGKNKELLNETVVALLQKSSNKVLASLFTNNTIAG---SASKATALKCK 663
Query: 1930 SRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGV 2109
+ G + + E + KLM L++T+PHFVRCI PN K G ++ VL+QLRCNGV
Sbjct: 664 A-AGDDSQWNCVCWESINKLMADLKSTAPHFVRCINPNENKIPGVMDPFWVLQQLRCNGV 722
Query: 2110 LEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKN-FIDGKESVRKMITALDIDTNLYRI 2286
LEG R+C + FP R+ + +F+ RY IL P + K+ F++ +++ +++ L+ID + Y+
Sbjct: 723 LEGTRVCCKAFPIRMLYDDFKQRYCILNPRIFSKSKFVNIRKATEEVLALLEIDQSQYQC 782
Query: 2287 GQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNG 2466
G +KVFF+ +L LEE RD K++ + FQA+ RG L R + N
Sbjct: 783 GVTKVFFKARILDRLEERRDEKISKVFTLFQARARGKLMRITFQKILEERDALALIQENI 842
Query: 2467 LAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLD 2646
A++ ++ W W LF KVKPL + +EI +E ++ L E E + K
Sbjct: 843 RAFIAVKTWPWMGLFFKVKPLAKSVGAGEEIAGLKEECAQLQKSLETSESQREELKTKQV 902
Query: 2647 QVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXX 2826
++ ER + QLQ E E A +++ L ELE + ++ R+
Sbjct: 903 SLVQERNDLLLQLQAEQETLANSEELCESLIKSKIELEAKIKELSRRVEEEEEINSELTA 962
Query: 2827 XRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXX 3006
RK + + K + +
Sbjct: 963 RGRKLEDECSELKKEIYDLEAILAKSEKAKCAAEHKVRNLTEEVHSLHEDVSKLTRAMQA 1022
Query: 3007 XXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAE 3186
L EE+ + K +L Q+ LE DL RER+ + + E+ K KL E
Sbjct: 1023 AQEAQQQTQEHLHIEEEKLSNVSKVNQKLSQQVDALEGDLERERKARMKCEKEKHKLEGE 1082
Query: 3187 LEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDEL 3366
L +L + + E+ ++ + E V+ +QK ++++QT I L
Sbjct: 1083 L-------------------KLNQEEFEMGQMNSKVENEKNLVSQLQKTVKELQTQILNL 1123
Query: 3367 REDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEA--TMLQDLMSRKDEEVNATK- 3537
+E++E+ER R K E R ++ LE D+ ++++EA T L + + +E K
Sbjct: 1124 KEELESERTIRAKVERERGDLAQDLE----DLNERLEEAGGTSLAQMEITRQQEARFQKL 1179
Query: 3538 -RAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQE 3714
+E+ E K + + V EL Q+E ++ R L+++++ + D+
Sbjct: 1180 RHDMEETTRHFEATSVSLKRRHAENVAELEGQVEHLQQVRQVLDQEKSDLQLQVDDLLTR 1239
Query: 3715 IALLQASRADIDKKRKIHEAHLMEIQANLAESD------------------------EHK 3822
+ + ++A+ +K ++E L E L E+ E K
Sbjct: 1240 VDQMARAKANAEKLCGLYERRLNEANTKLDEATQLAKDLTSQRTKLQNESGEFFKRLEEK 1299
Query: 3823 RTLIDQLERSRDEL----DHLN-RVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRL 3987
LI QL R + L + L ++ EE + A +++ ++ +
Sbjct: 1300 EALISQLSREKSNLILQVEELRVQLEEESKIVLALLEKIMSLPKIAFRMVKSACVRLLQS 1359
Query: 3988 KIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEE 4167
+ A + + + + + L ++ EE + +++ L + + + + R K E Q+ E+
Sbjct: 1360 QSALAHALQSTKHDYDLLREQYEEEQEVKSELHRALSKGNKETVQWRTKYEHDAMQRTED 1419
Query: 4168 LRKKNLRDVEHLQKQLEESEVAKER---ILQSKKKIQQELEDSSMELENVRASHRDSEKR 4338
L + + LQ+ E EV+ + + +++ ++Q EL D+ +L R+ ++
Sbjct: 1420 LEEAKKKLAIRLQEAAEAMEVSNAKNASLERARHRLQLELGDALSDLGKARSVAAALGQK 1479
Query: 4339 QKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSL 4518
Q+ + +A + ++A A +E R +L +EV ++++ EES+ + +L
Sbjct: 1480 QQHSDKALASWKQKQEEAQELLQASQKEAR-------ALSSEVLMLRQACEESNEAQETL 1532
Query: 4519 QQELQD------SISNKDDFG-KNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDAR 4677
+++ QD ++N+ G KN+ E+EKAK+ +E E +++ ++EE E L+ E
Sbjct: 1533 KRQNQDLQERICCLTNQVREGIKNLTEVEKAKKLIEQEKTEIQARLEEAEGALERNESKI 1592
Query: 4678 LRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKI 4857
LR ++ K+E R +S K+ EA R + + L++ L++E + A RKKI
Sbjct: 1593 LRFQLDLSEAKAELGRKLSEKEDEAGRLREKHQQALGSLQSSLDSEASSRIEATKMRKKI 1652
Query: 4858 ENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKF 5037
E + E+E QL ANR + + Q +++ +D+ + A+++
Sbjct: 1653 EGDLKEMEIQLCTANRQVSQTTRALGQLQSQMKDLQQHLDDSIYQNKDLKDQVALAEQRN 1712
Query: 5038 RAVEAEREQLREANE----GLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQX 5205
+++E E+LR E G A K+ + + S +K++LEA +AQ
Sbjct: 1713 ILLQSELEELRSLQEQTERGRKLAEKELLEATERISLFHTQNASLLS-QKKKLEADVAQA 1771
Query: 5206 XXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKI 5385
C+ A +K +K + + +L E+ N E ++++E++ +D + ++
Sbjct: 1772 QKEAGEMLQACQKAEEKAKKTAAEAANMWEELKKEQDTNAHLERTRKNMEQTIKDLQKRL 1831
Query: 5386 TELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDE 5565
E E A ++ Q+ LE++V+ LE +L E + A R ARRLE+ + + T Q E++
Sbjct: 1832 DEAEQTAVVGSKKQIQKLESRVRDLEGELESEVRRSAEAQREARRLERGIKELTYQAEED 1891
Query: 5566 KRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANE 5727
K+ + + L +K LK ++ ++Q++ E + ++ +K++ Q E ++ + E
Sbjct: 1892 KKNLSRMQALSDKLQLKVQSYKQQVEAVEAQANQYLSKYKKQQHELNEAKERAE 1945
Score = 57.0 bits (136), Expect = 5e-06
Identities = 63/289 (21%), Positives = 115/289 (38%), Gaps = 41/289 (14%)
Frame = +1
Query: 4990 AKEDIAALLREA---DRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGI 5160
A E+IA L E + E++RE+L+ L+Q R A +
Sbjct: 869 AGEEIAGLKEECAQLQKSLETSESQREELKTKQVSLVQERNDLLLQLQAEQETLANSEEL 928
Query: 5161 SS---EEKRRLEAKIAQXXXXXXXXQS-NCELAIDKQRKAQVQLEQITTDLSMERTLNQK 5328
+ K LEAKI + + N EL + RK + + ++ ++ + K
Sbjct: 929 CESLIKSKIELEAKIKELSRRVEEEEEINSELTA-RGRKLEDECSELKKEIYDLEAILAK 987
Query: 5329 TEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANR 5508
+E K + E R+ ++ L RA AA EA+ Q ++ L++E ++ + ++
Sbjct: 988 SEKAKCAAEHKVRNLTEEVHSLHEDVSKLTRAMQAAQEAQ-QQTQEHLHIEEEKLSNVSK 1046
Query: 5509 AARRLEKRLNDTTQQFEDEKRAN------------------------------EQAKELL 5598
++L ++++ E E++A E K L+
Sbjct: 1047 VNQKLSQQVDALEGDLERERKARMKCEKEKHKLEGELKLNQEEFEMGQMNSKVENEKNLV 1106
Query: 5599 EKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQRE----ADDLLDANEQL 5733
+ + L+ Q+ ++E+ ERT V+RE A DL D NE+L
Sbjct: 1107 SQLQKTVKELQTQILNLKEELESERTIRAKVERERGDLAQDLEDLNERL 1155
Score = 50.1 bits (118), Expect = 7e-04
Identities = 49/250 (19%), Positives = 114/250 (45%), Gaps = 9/250 (3%)
Frame = +1
Query: 3037 QLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAE 3216
+L +E+ + G K E +L E + ++ + L K+KL A++ ++ E
Sbjct: 1721 ELRSLQEQTERGRKLA---EKELLEATERISLFHTQNASLLSQKKKLEADVAQAQKEAGE 1777
Query: 3217 KMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDM-ETERN 3393
+ ++ + K E + +E +++ ++M+ TI +L++ + E E+
Sbjct: 1778 MLQACQKAEEKAKKTAAEAANMWEELKKEQDTNAHLERTRKNMEQTIKDLQKRLDEAEQT 1837
Query: 3394 AR-------NKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQ 3552
A K E R++ +LE + EA L+ + + K+ + +
Sbjct: 1838 AVVGSKKQIQKLESRVRDLEGELESEVRRSAEAQREARRLERGIKELTYQAEEDKKNLSR 1897
Query: 3553 IQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQ-EIALLQ 3729
+Q + K++ + + +QVE + Q Q+ + + + + N+A +ERA+ A+ ++ L+
Sbjct: 1898 MQ-ALSDKLQLKVQSYKQQVEAVEAQANQYLSKYKKQQHELNEA-KERAEAAESQVNKLR 1955
Query: 3730 ASRADIDKKR 3759
A ++++KR
Sbjct: 1956 ARAKELERKR 1965
>gi|49073352|ref|XP_400901.1| hypothetical protein UM03286.1 [Ustilago
maydis 521]
gi|46099040|gb|EAK84273.1| hypothetical protein UM03286.1 [Ustilago
maydis 521]
Length = 1830
Score = 900 bits (2326), Expect = 0.0
Identities = 593/1816 (32%), Positives = 930/1816 (50%), Gaps = 105/1816 (5%)
Frame = +1
Query: 37 AVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKA 216
+ +D A+ A +A +K W+PD G+L + +E D+ L L D S + T+ ++ K
Sbjct: 44 SASDAASAAEFASKKYVWIPDSAAGYLSAWVIKEEGDQSLCALQDGSNR-TVPTFELSKM 102
Query: 217 NPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLI 396
NPPKFDK+ED+++LT+LNEASV+HNL+ RY+SSLIYTYSGLF V +NPY LPIY++ ++
Sbjct: 103 NPPKFDKVEDIADLTFLNEASVVHNLRQRYFSSLIYTYSGLFLVAVNPYHTLPIYTDAIV 162
Query: 397 EEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVA 576
+KG++R E PH+FA+AD A R+M+ RE+QS+L TGESGAGKTENTKKVIQYLA +A
Sbjct: 163 AAYKGRRREENAPHVFALADEAMRNMIDNRENQSLLITGESGAGKTENTKKVIQYLASIA 222
Query: 577 G-------ATRNKSLNAAAQQNIVQKPDVRNPI-----GELEHQLLQANPILEAFGNSKT 720
+ SL ++ + ++ + + P+ G LE Q+LQANPILEAFGN++T
Sbjct: 223 ADPAAHTSQSPANSLTPSSSREVLDRINGVEPVSSKRLGLLERQILQANPILEAFGNAQT 282
Query: 721 VKNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSA 900
++N+NSSRFGKF+RI F G I+GANI++YLLEKSRV ++++ERSFHIFYQ+LRG
Sbjct: 283 IRNNNSSRFGKFVRIEFTSVGAIAGANIDWYLLEKSRVAIRSENERSFHIFYQLLRGAEP 342
Query: 901 KEKSEYLL-EGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSA 1077
+ K + LL D+Y +L + VDD E+ +++ +GF +E ++ RV +A
Sbjct: 343 ELKQKLLLTSSPDDYAYLKGTRKHVEGVDDSAEWKLLRDALNTVGFMPEEQLNLFRVAAA 402
Query: 1078 VLLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQ 1257
+L +GN++ ++ S+QA + + ++K+CH+LGLP + KA LRPR+K GRE+V ++
Sbjct: 403 ILQIGNIQLATDR-SEQARITNMPQVEKICHVLGLPEQDFSKALLRPRVKAGREWVTSSR 461
Query: 1258 NQEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFE 1437
Q + A++K YE+ F WLV RINK+LDR + +SFIG+LDIAGFEIFD+NSFE
Sbjct: 462 TMRQVSEEMAALSKTLYEKAFGWLVDRINKALDRPTSK-SSFIGVLDIAGFEIFDVNSFE 520
Query: 1438 QICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEK--PMGVLA 1611
Q+CINYTNEKLQQ FN+ MF+LEQEEY RE IEWDF++FGLDLQPTIDLIE P+G+L+
Sbjct: 521 QLCINYTNEKLQQFFNHHMFVLEQEEYARENIEWDFVNFGLDLQPTIDLIESTTPIGILS 580
Query: 1612 LLDEECLFPKANDKSFVEKLQKTHNKHPKFIVPDM---------------------RSKS 1728
LDEEC+ PKA D +F EKL + + D R
Sbjct: 581 CLDEECIMPKATDLTFTEKLNRIWGTNKDGSATDAAGAAMAAEKGLAHGSTKYARTRFAQ 640
Query: 1729 HFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMN 1908
F V HYAG V+Y D WL KN DPLN+N+ +M STD F+A ++ AE+A +
Sbjct: 641 GFVVKHYAGDVEYRTDGWLDKNKDPLNDNLTRVMSESTDRFIASLF--AEYAEVDEETSL 698
Query: 1909 ETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLE 2088
+A R ++G FRTV Q HKEQL LM L +T PHFVRCI+PN EKK GK+N LVLE
Sbjct: 699 ASAPKRRIKRGAFRTVGQRHKEQLNSLMGQLSSTQPHFVRCIVPNPEKKPGKMNVPLVLE 758
Query: 2089 QLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDID 2268
QLRCNGVLEGIRI R G+PNR+ F EFR+RYE+LTP +IP ++DG+++ ++M+ AL++D
Sbjct: 759 QLRCNGVLEGIRIARLGYPNRLLFSEFRNRYEVLTPGIIPPGYMDGRKACQRMVEALELD 818
Query: 2269 TNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXX 2448
++IG SK+FF+ GVLA +EE RD L + F A CR + +RR
Sbjct: 819 KLTFKIGTSKIFFKAGVLAEMEERRDSHLYDIFSRFGAACRMYTARRQMKKILNRAAAVR 878
Query: 2449 XXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRE 2628
N Y+KLR W WW+L+T+V+PLL TR D+E++ K EL ER + + +
Sbjct: 879 TVQRNARLYVKLREWPWWQLYTRVRPLLTATRHDEELKRKQLELAMVTERAERDQKEREA 938
Query: 2629 NEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXX 2808
E Q+ E+ I+EQL E + D + R + R LE + ++ +
Sbjct: 939 LEALKFQLESEKRKIEEQLISERSLLLDKDQVLARSKERESALEDDLAALQSDVDLLEGQ 998
Query: 2809 XXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXX 2988
++ + + ++ + +
Sbjct: 999 LEKALASQKATEQAHAELKLAFDQAADHLLRLEAEQKAWKEKEDTFMRDLSKHSTNAEQF 1058
Query: 2989 XXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHK 3168
L+ +L + E+ +A R+ + E+E L E + E ++
Sbjct: 1059 RTERQVFVTERDDLSRKLQEKEQDLD---RAHKRMMTAVQEVEAKLLAEANGRQEEQKRA 1115
Query: 3169 RKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQ 3348
+L + S ++E ++ ++++E+ + + S + K++ D+
Sbjct: 1116 LQLEEQTRQSSYQISELQRVAAGYEARVKEKEQEVSQLQKQVSDLSRERESLSKKLEDLG 1175
Query: 3349 TTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVN 3528
+ L D+++ ++ K R A L+K ++DE L + S +D +
Sbjct: 1176 LKVSTLTFDVKSAKDEHAKTSQAR----ATLQK-------ELDETRRLMEAKSSEDVKTK 1224
Query: 3529 ATKRAIEQIQHTMEGKIEEQKAKFSRQV-EELHDQIEQHKKQRSQLEKQQNQADQERADM 3705
R EQ T + EQ A R++ E H +EQ R+++ Q +A A
Sbjct: 1225 EIHRMKEQELQT----LREQMASVQRELFETKHSNLEQISALRAEISAAQKEAQAHGA-- 1278
Query: 3706 AQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVR 3885
A++ A +Q A E + E +A +++ KR L+ ++ + +NR
Sbjct: 1279 ARQGAEVQLREA---------EVRVRETDTKIAAAEKAKREAETLLQEAQSKSAVINRGL 1329
Query: 3886 EEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAE 4065
++ A ++++L A R + + ++A Q+ E +A +E E
Sbjct: 1330 QDALKNKATLEKQLQAAATKHQDLEDALLELERNEASWKHKADQVAVELSAESKRRELLE 1389
Query: 4066 GLRAHLEKEIHAARQ-GAGEARR----KAEESVNQQ-------------------LEELR 4173
E+ ++ +Q AG+ + K E ++ QQ LEE +
Sbjct: 1390 QAHKQAERNANSLQQLVAGKDKEISGLKHELTLAQQEMRRLQSMQNKTIVEHVHVLEEAK 1449
Query: 4174 KKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELE----------------- 4302
K R + Q +L+E + + +SK ++ E ED + E+
Sbjct: 1450 KYTDRQLADAQSKLQELAHYTKTLEKSKARLANENEDLTREVSRLQRAAGGSATATASAK 1509
Query: 4303 ---------------NVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRE 4437
NV S D+ K KK E +++E ++++A RD R ++
Sbjct: 1510 VGNGVGLRGAVTTFGNVAPSSGDA-KSIKKLEDKVSELASSLKQAQQQRDEALSNARRKD 1568
Query: 4438 TRVLSLLNEVDIMKE-HLEESDRVRRSLQQELQDSISNKDDFGKNVH----ELEKAKRSL 4602
+ +++ E H++E +R ++ Q +++N ++ H E + L
Sbjct: 1569 LQADEMVSRAKRQYESHIQELERQLKNSQIARSTTMTNLEELILAGHGSPREPAGSSDGL 1628
Query: 4603 EAE-LNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGL-- 4773
+ L+++R EELE ++ D + +++ + R SN V + + +
Sbjct: 1629 RHQILDELRRGHEELEQDIAAKSDLLRNHKAPTNGVQAAA-RGSSNYYVYDKPRMQNASG 1687
Query: 4774 ----LKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXX 4941
R+LE++L R + ++S+++ + Q+ +L Q+ L+ +
Sbjct: 1688 SGSSTHSDRELESKLAEMTRAYNESLSNQRSTQAQMSQLVTQI---RDLQSDLDQTELKY 1744
Query: 4942 XXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXX 5121
YQ +EA + I L ++ + E R + M+ KQ
Sbjct: 1745 DQLAAAYQCLIQEAGVDEGMIQNLQATLEKYKNQADKHMESWRSST---MELEKQ--TAS 1799
Query: 5122 XXXXXXRAKGGGISSE 5169
R +G I+ E
Sbjct: 1800 LRNSVGRGRGASINGE 1815
Score = 90.9 bits (224), Expect = 3e-16
Identities = 181/938 (19%), Positives = 368/938 (38%), Gaps = 109/938 (11%)
Frame = +1
Query: 3256 KRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVA 3435
+ DEEL+ R E A VT ++ + + ++ L+ +E+E+ + ++ R ++
Sbjct: 910 RHDEELK----RKQLELAMVTERAERDQKEREALEALKFQLESEKRKIEEQLISERSLLL 965
Query: 3436 QLEKVKGDVLDKV----DEATMLQ---DLMSRKDEEVNATKRAIEQIQHTMEGKIE---- 3582
++V ++ D+ LQ DL+ + E+ A+++A EQ ++ +
Sbjct: 966 DKDQVLARSKERESALEDDLAALQSDVDLLEGQLEKALASQKATEQAHAELKLAFDQAAD 1025
Query: 3583 -------EQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRA 3741
EQKA ++ + D + +H Q ++ ER D++++ LQ
Sbjct: 1026 HLLRLEAEQKAWKEKEDTFMRD-LSKHSTNAEQFRTERQVFVTERDDLSRK---LQEKEQ 1081
Query: 3742 DIDKKRKIHEAHLMEIQANL-----AESDEHKRTLI--DQLERSRDELDHLNRVR----- 3885
D+D+ K + E++A L +E KR L +Q +S ++ L RV
Sbjct: 1082 DLDRAHKRMMTAVQEVEAKLLAEANGRQEEQKRALQLEEQTRQSSYQISELQRVAAGYEA 1141
Query: 3886 --EEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEE 4059
+E+E + +Q++++ +L+ + + D K+A DE +
Sbjct: 1142 RVKEKEQEVSQLQKQVSDLSRERESLSK------KLEDLGLKVSTLTFDVKSAK-DEHAK 1194
Query: 4060 AEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKE 4239
RA L+KE+ R+ +A+ S + + +E+ + ++++ L++Q+
Sbjct: 1195 TSQARATLQKELDETRR-----LMEAKSSEDVKTKEIHRMKEQELQTLREQMAS------ 1243
Query: 4240 RILQSKKKIQQEL-EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMS 4416
+Q+EL E LE + A + QK+ ++ A R
Sbjct: 1244 --------VQRELFETKHSNLEQISALRAEISAAQKEAQAHGAA-----------RQGAE 1284
Query: 4417 QELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKR 4596
+LR+ E RV E D + +++ +R + LQ++ S + + + K K
Sbjct: 1285 VQLREAEVRV----RETD---TKIAAAEKAKREAETLLQEAQSKSAVINRGLQDALKNKA 1337
Query: 4597 SLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLL 4776
+LE +L + ++L EDA L LE + K ++D+ ++ AE KRR LL
Sbjct: 1338 TLEKQLQAAATKHQDL-------EDALLELERNEASWKHKADQVA--VELSAESKRRELL 1388
Query: 4777 ----KQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXX 4944
KQ N L+ GK + +I L+ +L +A ++E
Sbjct: 1389 EQAHKQAERNANSLQQLVAGK----------DKEISGLKHELTLA---QQEMRRLQSMQN 1435
Query: 4945 XXXXEYQIECEEARQAKE----DIAALLREADRKFRAVEAEREQLREANEGLMQ--ARKQ 5106
E+ EEA++ + D + L+E + +E + +L NE L + +R Q
Sbjct: 1436 KTIVEHVHVLEEAKKYTDRQLADAQSKLQELAHYTKTLEKSKARLANENEDLTREVSRLQ 1495
Query: 5107 XXXXXXXXXXXRAK-GGGI-----------------SSEEKRRLEAKIAQXXXXXXXXQS 5232
AK G G+ ++ ++LE K+++ Q
Sbjct: 1496 RAAGGSATATASAKVGNGVGLRGAVTTFGNVAPSSGDAKSIKKLEDKVSELASSLKQAQQ 1555
Query: 5233 NCELAIDKQRKAQVQLEQI---------------------------TTDLSMERTL---- 5319
+ A+ R+ +Q +++ TT ++E +
Sbjct: 1556 QRDEALSNARRKDLQADEMVSRAKRQYESHIQELERQLKNSQIARSTTMTNLEELILAGH 1615
Query: 5320 --------------NQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQY 5457
+Q + ++ E +D AK L + Q AA + Y
Sbjct: 1616 GSPREPAGSSDGLRHQILDELRRGHEELEQDIAAKSDLLRNHKAPTNGVQAAARGSSNYY 1675
Query: 5458 LEDQLNVEGQEKT-AANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRR 5634
+ D+ ++ + ++ + R LE +L + T+ + + + + + + R+L+
Sbjct: 1676 VYDKPRMQNASGSGSSTHSDRELESKLAEMTRAYNESLSNQRSTQAQMSQLVTQIRDLQS 1735
Query: 5635 QLDEAEDEMSRERTKHRNVQREA--DDLLDANEQLTRE 5742
LD+ E + + ++ + +EA D+ + N Q T E
Sbjct: 1736 DLDQTELKYDQLAAAYQCLIQEAGVDEGMIQNLQATLE 1773
Score = 73.2 bits (178), Expect = 7e-11
Identities = 123/619 (19%), Positives = 253/619 (40%), Gaps = 31/619 (5%)
Frame = +1
Query: 3982 RLKIANIN-RARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGE-----ARRKAEE 4143
+L++A + RA + + E+ AL K + E + +E+++ + R + AR K E
Sbjct: 919 QLELAMVTERAERDQKEREALEALKFQLESEKRKIEEQLISERSLLLDKDQVLARSKERE 978
Query: 4144 SVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHR 4323
S LE+ DV+ L+ QLE++ +++ Q+ +++ + ++ L + A +
Sbjct: 979 SA---LEDDLAALQSDVDLLEGQLEKALASQKATEQAHAELKLAFDQAADHLLRLEAEQK 1035
Query: 4324 DSEKRQKKFESQMAEE-------RVAVQKALLDRDAMSQELRDRET-------RVLSLLN 4461
++++ F +++ R Q + +RD +S++L+++E R+++ +
Sbjct: 1036 AWKEKEDTFMRDLSKHSTNAEQFRTERQVFVTERDDLSRKLQEKEQDLDRAHKRMMTAVQ 1095
Query: 4462 EVD--IMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQM 4635
EV+ ++ E + +R+LQ E Q S+ + EL++ EA + + ++
Sbjct: 1096 EVEAKLLAEANGRQEEQKRALQLEEQTRQSSYQ-----ISELQRVAAGYEARVKEKEQEV 1150
Query: 4636 EELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIR-DLENELEN 4812
+L+ Q+++ +R R ++ + + DV++ + Q R L+ EL+
Sbjct: 1151 SQLQK--QVSDLSRERESLSKKLEDLGLKVSTLTFDVKSAKDEHAKTSQARATLQKELDE 1208
Query: 4813 EKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQA 4992
+R S K + EQ+L+ L+E+ E+
Sbjct: 1209 TRRLMEAKSSEDVKTKEIHRMKEQELQT---LREQMASVQRELFETKHS---NLEQISAL 1262
Query: 4993 KEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEE 5172
+ +I+A +EA A + QLREA + + + I++ E
Sbjct: 1263 RAEISAAQKEAQAHGAARQGAEVQLREAEVRVRETDTK-----------------IAAAE 1305
Query: 5173 KRRLEAKIAQXXXXXXXXQSNCEL--------AIDKQRKAQVQLEQITTDLSMERTLNQK 5328
K + EA+ N L ++KQ +A Q D +E N+
Sbjct: 1306 KAKREAETLLQEAQSKSAVINRGLQDALKNKATLEKQLQAAATKHQDLEDALLELERNEA 1365
Query: 5329 TEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANR 5508
+ K ++K EL A +A +L+ V + +++ E T A +
Sbjct: 1366 SWKHKADQVAVELSAESKRRELLEQAHKQAERNANSLQQLVAGKDKEISGLKHELTLAQQ 1425
Query: 5509 AARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRN 5688
RRL+ N T + E+AK+ + RQL +A+ ++ +
Sbjct: 1426 EMRRLQSMQNKT---IVEHVHVLEEAKKYTD----------RQLADAQSKLQELAHYTKT 1472
Query: 5689 VQREADDLLDANEQLTREL 5745
+++ L + NE LTRE+
Sbjct: 1473 LEKSKARLANENEDLTREV 1491
Score = 49.7 bits (117), Expect = 9e-04
Identities = 67/313 (21%), Positives = 125/313 (39%), Gaps = 21/313 (6%)
Frame = +1
Query: 4834 AVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIA-- 5007
A H ++++ + EL E A R ++E ++Q+E E+ + ++ I+
Sbjct: 908 ATRHDEELKRKQLELAMVTERAERDQKE------REALEALKFQLESEKRKIEEQLISER 961
Query: 5008 ALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLE 5187
+LL + D+ A ERE E + +Q+ K + E+ E
Sbjct: 962 SLLLDKDQVL-ARSKERESALEDDLAALQSDVDLLEGQLEKALASQK-----ATEQAHAE 1015
Query: 5188 AKIAQXXXXXXXXQSNCELAIDKQR---------KAQVQLEQITTDLSMERT----LNQK 5328
K+A + E K++ K EQ T+ + T L++K
Sbjct: 1016 LKLAFDQAADHLLRLEAEQKAWKEKEDTFMRDLSKHSTNAEQFRTERQVFVTERDDLSRK 1075
Query: 5329 TEAEKQSLERSNRDYKAKITELESG----AQSRARAQMAALEAKVQYLEDQLNVEGQEKT 5496
+ ++Q L+R+++ + E+E+ A R Q AL+ + Q + + ++
Sbjct: 1076 LQEKEQDLDRAHKRMMTAVQEVEAKLLAEANGRQEEQKRALQLEEQTRQSSYQISELQRV 1135
Query: 5497 AANRAARRLEKR--LNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRE 5670
AA AR EK ++ +Q D R E + LE LK L + A+DE ++
Sbjct: 1136 AAGYEARVKEKEQEVSQLQKQVSDLSRERESLSKKLEDLGLKVSTLTFDVKSAKDEHAKT 1195
Query: 5671 RTKHRNVQREADD 5709
+Q+E D+
Sbjct: 1196 SQARATLQKELDE 1208
>gi|6682321|emb|CAB64663.1| pedal retractor muscle myosin heavy chain
[Mytilus galloprovincialis]
Length = 1708
Score = 892 bits (2305), Expect = 0.0
Identities = 521/1680 (31%), Positives = 898/1680 (53%), Gaps = 15/1680 (0%)
Frame = +1
Query: 715 KTVKNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGC 894
KT +N+NSSRFGKFIRI+F G I+GA+IE YLLEKSRV ER++H+FYQ++
Sbjct: 1 KTTRNNNSSRFGKFIRIHFGPDGKIAGADIETYLLEKSRVTFCLSAERNYHVFYQLMTP- 59
Query: 895 SAKEKSEYLLEGVDN--YRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRV 1068
+ K++ E +L D Y F+ +T+ ++DD +E + I+GF+ DE S +
Sbjct: 60 AMKDQHEMMLLTPDPALYTFINQGALTVDSIDDNEEMKLMDEAFDILGFSQDEKKSCYKC 119
Query: 1069 VSAVLLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVN 1248
+A+L +G ++F Q + +QA +KV LLG+ + K+ ++P+IKVG E V
Sbjct: 120 TAAILHMGEMKFKQ--RGEQAEPDGTTEAEKVSFLLGVNSNDFIKSLVKPKIKVGTEVVA 177
Query: 1249 KAQNQEQAEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDIN 1428
+++ ++Q ++ A++K+ Y+R+F WLV R+N SLD +++ +IG+LDIAGFEIFD N
Sbjct: 178 QSRTKQQVVNSISAMSKSLYDRVFNWLVKRVNHSLDTKNKRNY-YIGVLDIAGFEIFDFN 236
Query: 1429 SFEQICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVL 1608
+FEQ+CINYTNE+LQQ FN TMF+LEQEEY++EGI+W+FI+FG+DLQ IDLIEKPMG+L
Sbjct: 237 TFEQLCINYTNERLQQFFNYTMFVLEQEEYKKEGIQWEFINFGMDLQACIDLIEKPMGIL 296
Query: 1609 ALLDEECLFPKANDKSFVEKLQKTH-NKHPKFIVPDMRSKS---HFAVVHYAGRVDYSAD 1776
++L+E+C+FPKA+DKS E L H K P F P +K F + HYAG V Y+
Sbjct: 297 SILEEQCMFPKADDKSLKEMLFSNHMGKSPNFTKPGKAAKGANGDFELHHYAGIVPYNLK 356
Query: 1777 QWLMKNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFG---MRSRKGMF 1947
WL KN DP+NE VV L+Q S + V ++ AAE G + + F
Sbjct: 357 GWLDKNKDPINETVVQLLQQSKEHLVQTLF---------AAETPAEGSGGPKKKKKSSAF 407
Query: 1948 RTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRI 2127
+T+S +H+E L KLM L T PHFVRCIIPN K+ G I++ LVL QL+CNGVLEGIRI
Sbjct: 408 QTISAVHRESLNKLMKNLYATHPHFVRCIIPNELKQPGMIDAALVLNQLQCNGVLEGIRI 467
Query: 2128 CRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFF 2307
CR+GFP+R+ + EF+ RY IL +P+ F+DGK K++ AL +D Y++G +KVFF
Sbjct: 468 CRKGFPSRIIYAEFKQRYSILAASAVPQGFVDGKVVTEKVLLALQLDPAEYKLGNTKVFF 527
Query: 2308 RTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLR 2487
+ GVL +LE RD +L A+I QA R FL R+ Y N +L LR
Sbjct: 528 KAGVLGNLENMRDERLGAIISMMQAHIRAFLIRKAYKKLQDQRVGLSVIQRNIRKWLLLR 587
Query: 2488 NWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERA 2667
NWQWW+++ KVKP+L + R ++E++ K +E++ +E + K+E +E E K +++ ++
Sbjct: 588 NWQWWKMYAKVKPMLNIAREEEEMQKKLEEMKKMEEDIAKLEKIKKELEIKNVELLEQKN 647
Query: 2668 VIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQME 2847
+ QLQ E +N +L+ +L T+ E E + +M +RL ++K
Sbjct: 648 DMYLQLQSEQDNVVDLEQRVEQLITQKAEFESQMKEMEERLLDEEDAASELEGLKKKMEG 707
Query: 2848 TVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXG 3027
+ DKT+ D +
Sbjct: 708 ENSEMKRDIEDLETTLAKAEQDKTHKDNQIKTLQGEMAQQDEQISKLGKEKKNLEEVNKK 767
Query: 3028 LTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDH 3207
L E++ H K K +LE+ L E+E +L RE++ + ++E+ KRK+ +L+ +++
Sbjct: 768 TLADLQKEEDKVNHLNKIKAKLESTLDEMEDNLEREKKVRGDVEKSKRKVEQDLKATQEV 827
Query: 3208 LAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETE 3387
+ E G E+ + ++D EL +R ++ ++++++Q I+EL E++E E
Sbjct: 828 VEELEGVKREMEEAVRRKDVELNSLHSRIEDCEGVNANQSRKIKELQQIIEELEEELEAE 887
Query: 3388 RNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTM 3567
R AR K E R E+ +L+++ + ++ DL +++ E+ +R +E++
Sbjct: 888 RAARAKVEKQRNELARELDELSSQLEEQGGATQAQMDLNKKREHELMRLRREMEEMTLQS 947
Query: 3568 EGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADI 3747
E ++ + + K E+ DQI+Q K +S+LEK++ +E D+ +++ +R
Sbjct: 948 EAQVAQFRKKQQESNNEMADQIDQLNKLKSRLEKEKKDLKRELDDVQSQLSHSMKNRGVS 1007
Query: 3748 DKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRL 3927
DK K +E+ + EI + E+ + Q + + E+ +NR E+ EH ++ +
Sbjct: 1008 DKVAKQYESQISEITYKVEETQRTIVEINSQKSKLQSEVTEINRQLEDAEHTIGSLTKDK 1067
Query: 3928 ATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAAR 4107
+ TR++ + R L + +++ + EE + ++ L++++ A+
Sbjct: 1068 SALTSQLEEAKRSLEEETRMRQKFQSEVRNLNADVDSVRESLEEEQESKSDLQRQLSKAK 1127
Query: 4108 QGAGEARRKAE---ESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
A + R K E + +LEE ++K + ++ E + + ++K ++Q EL
Sbjct: 1128 NEAQQWRSKYETEGAAKADELEESKRKLSAKLAEAEQAAEAANAKASGLEKAKNRLQGEL 1187
Query: 4279 EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLL 4458
+D +E+E + EK+Q++F+ + E + V++ + D E R + +
Sbjct: 1188 DDLLIEVERSNVNSSTLEKKQRQFDRTIQEWTLKVKELQTEIDTAHTEARGYSAELFRVK 1247
Query: 4459 NEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQME 4638
+ + + +E R ++L E+++ D G++ HE+EKAKR LE E +++ +E
Sbjct: 1248 AQYEETSDTIEALRRENKNLADEIRELSDQLSDGGRSSHEIEKAKRRLEMEKEELQAALE 1307
Query: 4639 ELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEK 4818
E E L+ E +R ++ +++E DR I K+ E E RR + + ++ L+ E
Sbjct: 1308 EAESALEQEEAKVVRSQLEMSTIRTEIDRRIHEKEEEFENTRRNHQRALESMQISLDAEA 1367
Query: 4819 RGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKE 4998
+GK+ A RKK+E I ELE L+ +NR K E E ++ EE +A++
Sbjct: 1368 KGKAEAHRIRKKLEQDINELEMALDTSNRAKAEAEKNLKRYIVQIQELTLKLEEETRARD 1427
Query: 4999 DIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXX---XXXXXXXXRAKGGGISSE 5169
+ +R+ + +E +++R A E +ARK A +
Sbjct: 1428 ESRESYVMIERRCNLLVSEVDEVRSALEQSERARKTAESELYESQDRINELAAQVSSAQA 1487
Query: 5170 EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQS 5349
+KR++E + Q+ + A D+ ++A + +++ +L E+ + + E +++
Sbjct: 1488 QKRKVEGDMQAMSADLDELQNEIKAADDRAKRAVMDTTRLSDELRAEQEHSSQIEKMRKT 1547
Query: 5350 LERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEK 5529
LE + ++ ++ E E+ R +A LE +VQ LE +L+ E + + R+ ++
Sbjct: 1548 LEITIKELHVRVDEAEASGVKGGRKVIAKLEQRVQDLESELDNEQRRHAETQKNMRKADR 1607
Query: 5530 RLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
R+ + Q +++++ E+ ++++K K + +RQ++EAE+ + K+R VQ E +D
Sbjct: 1608 RMKELAFQCDEDRKGQERLTDMIDKLQSKVKTFKRQVEEAEEIAAINLAKYRKVQAELED 1667
Score = 178 bits (452), Expect = 1e-42
Identities = 168/914 (18%), Positives = 398/914 (43%), Gaps = 16/914 (1%)
Frame = +1
Query: 3052 EERAKHGVKAKGRLENQLHELEQDLNRERQYKS-ELEQHKRKLLAELEDSKDHLAEKMGK 3228
EE + ++ ++E + +LE+ + +E + K+ EL + K + +L+ +D++ + +
Sbjct: 608 EEEMQKKLEEMKKMEEDIAKLEK-IKKELEIKNVELLEQKNDMYLQLQSEQDNVVDLEQR 666
Query: 3229 VEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKA 3408
VE+L Q + + +++ R +E + ++ + M+ E++ D+E KA
Sbjct: 667 VEQLITQKAEFESQMKEMEERLLDEEDAASELEGLKKKMEGENSEMKRDIEDLETTLAKA 726
Query: 3409 EMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQ 3588
E + Q++ ++G++ + ++ + L + EEVN A Q + + +
Sbjct: 727 EQDKTHKDNQIKTLQGEMAQQDEQISKLGK-EKKNLEEVNKKTLADLQKEEDKVNHLNKI 785
Query: 3589 KAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIH 3768
KAK ++E+ D +E+ KK R +EK + + +Q+ + + L+ + ++++ +
Sbjct: 786 KAKLESTLDEMEDNLEREKKVRGDVEKSKRKVEQDLKATQEVVEELEGVKREMEEAVRRK 845
Query: 3769 EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXX 3948
+ L + + + + + +++ + ++ L E E A A ++++
Sbjct: 846 DVELNSLHSRIEDCEGVNANQSRKIKELQQIIEELEEELEAERAARAKVEKQ-------- 897
Query: 3949 XXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEAR 4128
AR+L DE ++ L+E+ A + L K+ R
Sbjct: 898 ----------------RNELAREL-DELSSQLEEQGGATQAQMDLNKK---REHELMRLR 937
Query: 4129 RKAEESVNQ---QLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMEL 4299
R+ EE Q Q+ + RKK + Q+++ K R+ + KK +++EL+D +L
Sbjct: 938 REMEEMTLQSEAQVAQFRKKQQESNNEMADQIDQLNKLKSRLEKEKKDLKRELDDVQSQL 997
Query: 4300 ENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMK 4479
+ + S+K K++ESQ++E V++ + + + ++ L +EV +
Sbjct: 998 SHSMKNRGVSDKVAKQYESQISEITYKVEET-------QRTIVEINSQKSKLQSEVTEIN 1050
Query: 4480 EHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQ 4659
LE+++ SL ++ S ++ +++ E + ++ ++E+ ++ ++ + ++L+
Sbjct: 1051 RQLEDAEHTIGSLTKDKSALTSQLEEAKRSLEEETRMRQKFQSEVRNLNADVDSVRESLE 1110
Query: 4660 IAEDARLRLEVTNQALKSESDRAISNKDVEA-------EEKRRGLLKQIRDLENELENEK 4818
++++ L+ K+E+ + S + E EE +R L ++ + E E
Sbjct: 1111 EEQESKSDLQRQLSKAKNEAQQWRSKYETEGAAKADELEESKRKLSAKLAEAEQAAEAAN 1170
Query: 4819 RGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKE 4998
SG + +++ ++ +L ++E +N E+ ++ +E + +
Sbjct: 1171 AKASGLEKAKNRLQGELDDLLIEVERSNVNSSTLEKKQRQFDRTIQEWTLKVKELQTEID 1230
Query: 4999 DIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSE--- 5169
R + V+A+ E+ + E L + K + GG S E
Sbjct: 1231 TAHTEARGYSAELFRVKAQYEETSDTIEALRRENKNLADEIRELSDQLSDGGRSSHEIEK 1290
Query: 5170 EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQS 5349
KRRLE + + +S E K ++Q+++ I T++ +R +++K E + +
Sbjct: 1291 AKRRLEMEKEELQAALEEAESALEQEEAKVVRSQLEMSTIRTEI--DRRIHEKEEEFENT 1348
Query: 5350 LERSNRDYKAKITELESGAQSRARAQMAA--LEAKVQYLEDQLNVEGQEKTAANRAARRL 5523
R ++ L++ A+ +A A LE + LE L+ + K A + +R
Sbjct: 1349 RRNHQRALESMQISLDAEAKGKAEAHRIRKKLEQDINELEMALDTSNRAKAEAEKNLKRY 1408
Query: 5524 EKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREA 5703
++ + T + E+E RA ++++E + L ++DE + + + + E
Sbjct: 1409 IVQIQELTLKLEEETRARDESRESYVMIERRCNLLVSEVDEVRSALEQSERARKTAESEL 1468
Query: 5704 DDLLDANEQLTREL 5745
+ D +L ++
Sbjct: 1469 YESQDRINELAAQV 1482
Score = 168 bits (425), Expect = 2e-39
Identities = 181/919 (19%), Positives = 363/919 (38%), Gaps = 65/919 (7%)
Frame = +1
Query: 2521 KPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKL-DQVIVERAVIQEQLQQES 2697
K L + + +D++ + +++A E L D E EKK+ V + +++ L+
Sbjct: 767 KTLADLQKEEDKVNHLN-KIKAKLESTLDEMEDNLEREKKVRGDVEKSKRKVEQDLKATQ 825
Query: 2698 ENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXX 2877
E EL+ ++ ++ + + +N + R+ ++ + + +
Sbjct: 826 EVVEELEGVKREMEEAVRRKDVELNSLHSRIEDCEGVNANQSRKIKELQQIIEELEEELE 885
Query: 2878 XXXXXXXXXXXDKTNV----DQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLL 3045
+ + D+ Q D + L
Sbjct: 886 AERAARAKVEKQRNELARELDELSSQLEEQGGATQAQMDLNKKREHELMRLRREMEEMTL 945
Query: 3046 DHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMG 3225
E + K + N++ + LN+ KS LE+ K+ L EL+D + L+ M
Sbjct: 946 QSEAQVAQFRKKQQESNNEMADQIDQLNK---LKSRLEKEKKDLKRELDDVQSQLSHSM- 1001
Query: 3226 KVEELNNQLMKRDEELQHQLTRYDEES---------------ANVTLMQKQMRDMQTTID 3360
K +++++ K+ E ++T EE+ + VT + +Q+ D + TI
Sbjct: 1002 KNRGVSDKVAKQYESQISEITYKVEETQRTIVEINSQKSKLQSEVTEINRQLEDAEHTIG 1061
Query: 3361 ELRED--------------METERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQD 3498
L +D +E E R K + R + A ++ V+ + ++ + + LQ
Sbjct: 1062 SLTKDKSALTSQLEEAKRSLEEETRMRQKFQSEVRNLNADVDSVRESLEEEQESKSDLQR 1121
Query: 3499 LMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQN 3678
+S+ E + E ++EE K K S ++ E E + S LEK +N
Sbjct: 1122 QLSKAKNEAQQWRSKYETEGAAKADELEESKRKLSAKLAEAEQAAEAANAKASGLEKAKN 1181
Query: 3679 QADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRD 3858
+ E D+ E+ + + ++KK++ + + E + E T +
Sbjct: 1182 RLQGELDDLLIEVERSNVNSSTLEKKQRQFDRTIQEWTLKVKELQTEIDTAHTEARGYSA 1241
Query: 3859 ELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNA 4038
EL + EE ++R R R+LE EK
Sbjct: 1242 ELFRVKAQYEETSDTIEALRRENKNLADEIRELSDQLSDGGRSSHEIEKAKRRLEMEKEE 1301
Query: 4039 LLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEEL---RKKNLRDVEHLQK 4209
L EEAE E ++ ++ R + + ++++ EE R+ + R +E +Q
Sbjct: 1302 LQAALEEAESALEQEEAKVVRSQLEMSTIRTEIDRRIHEKEEEFENTRRNHQRALESMQI 1361
Query: 4210 QLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQK 4389
L+ K + +KK++Q++ + M L+ + ++EK K++ Q+ E + +++
Sbjct: 1362 SLDAEAKGKAEAHRIRKKLEQDINELEMALDTSNRAKAEAEKNLKRYIVQIQELTLKLEE 1421
Query: 4390 ALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKN 4569
RD + E R L++EVD ++ LE+S+R R++ + EL +S ++
Sbjct: 1422 ETRARDESRESYVMIERRCNLLVSEVDEVRSALEQSERARKTAESELYESQDRINELAAQ 1481
Query: 4570 VHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLR---------------------- 4683
V + KR +E ++ M ++EL++ ++ A+D R
Sbjct: 1482 VSSAQAQKRKVEGDMQAMSADLDELQNEIKAADDRAKRAVMDTTRLSDELRAEQEHSSQI 1541
Query: 4684 ------LEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSH 4845
LE+T + L D A ++ + L ++++DLE+EL+NE+R + +
Sbjct: 1542 EKMRKTLEITIKELHVRVDEAEASGVKGGRKVIAKLEQRVQDLESELDNEQRRHAETQKN 1601
Query: 4846 RKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREA 5025
+K + ++ EL Q + + +E ++ + EEA E+IAA+
Sbjct: 1602 MRKADRRMKELAFQCDEDRKGQERLTDMIDKLQSKVKTFKRQVEEA----EEIAAINL-- 1655
Query: 5026 DRKFRAVEAEREQLREANE 5082
K+R V+AE E E E
Sbjct: 1656 -AKYRKVQAELEDAEERAE 1673
Score = 85.1 bits (209), Expect = 2e-14
Identities = 97/459 (21%), Positives = 180/459 (39%), Gaps = 10/459 (2%)
Frame = +1
Query: 3028 LTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLA---ELEDS 3198
L+ QL D + KAK RLE + EL+ L + +S LEQ + K++ E+
Sbjct: 1274 LSDQLSDGGRSSHEIEKAKRRLEMEKEELQAALE---EAESALEQEEAKVVRSQLEMSTI 1330
Query: 3199 KDHLAEKMG-KVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELRED 3375
+ + ++ K EE N L+ D E+ + + ++ I+EL
Sbjct: 1331 RTEIDRRIHEKEEEFENTRRNHQRALESMQISLDAEAKGKAEAHRIRKKLEQDINELEMA 1390
Query: 3376 METERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQI 3555
++T A+ +AE + + Q+ Q+L + +EE A + E
Sbjct: 1391 LDTSNRAKAEAEKNLKRYIVQI-----------------QELTLKLEEETRARDESRESY 1433
Query: 3556 QHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQAS 3735
IE + +V+E+ +EQ ++ R E + ++ ++A +++ QA
Sbjct: 1434 V-----MIERRCNLLVSEVDEVRSALEQSERARKTAESELYESQDRINELAAQVSSAQAQ 1488
Query: 3736 RADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANM 3915
+ ++ + A L E+Q + +D+ + + R DEL R E+EH+
Sbjct: 1489 KRKVEGDMQAMSADLDELQNEIKAADDRAKRAVMDTTRLSDEL------RAEQEHSSQIE 1542
Query: 3916 QRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEI 4095
+ R +LE L E + + A +K +
Sbjct: 1543 KMRKTLEITIKELHVRVDEAEASGVKGGRKVIAKLEQRVQDLESELDNEQRRHAETQKNM 1602
Query: 4096 HAARQGAGEAR------RKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSK 4257
A + E RK +E + +++L+ K V+ ++Q+EE+E L
Sbjct: 1603 RKADRRMKELAFQCDEDRKGQERLTDMIDKLQSK----VKTFKRQVEEAEEIAAINLAKY 1658
Query: 4258 KKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEER 4374
+K+Q ELED+ E +S K + K S M+ R
Sbjct: 1659 RKVQAELEDAE---ERAESSEASLTKLRTKNRSSMSSTR 1694
>gi|49094764|ref|XP_408843.1| hypothetical protein AN4706.2
[Aspergillus nidulans FGSC A4]
gi|40741558|gb|EAA60748.1| hypothetical protein AN4706.2 [Aspergillus
nidulans FGSC A4]
Length = 2404
Score = 887 bits (2293), Expect = 0.0
Identities = 620/1915 (32%), Positives = 964/1915 (49%), Gaps = 50/1915 (2%)
Frame = +1
Query: 79 KLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSEL 258
K W+ D + F+ G + E + L+ D +Q + D V + NP KFDK +DM+EL
Sbjct: 118 KYVWLRDPEKAFVKGLVLEEQDGARLLVQTDDGQQREVDVDQVDRVNPAKFDKADDMAEL 177
Query: 259 TYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPH 438
T+LNEASV+HNL RY + LIYTYSGLF V +NPY LPIYS + I +KG+ R E PH
Sbjct: 178 THLNEASVVHNLHTRYLADLIYTYSGLFLVTVNPYCPLPIYSNEYINMYKGQSREETRPH 237
Query: 439 IFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQ 618
IFA+AD A+R++++E E+QSIL TGESGAGKTENTKKVIQYLA VA + S + + Q
Sbjct: 238 IFAMADEAFRNLVEEGENQSILVTGESGAGKTENTKKVIQYLAAVATSDNMYSRSGSKQM 297
Query: 619 NIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGA 798
N L Q+L+ANPILEAFGNS+TV+N+NSSRFGKFIRI F SG ISGA
Sbjct: 298 N------------TLSQQILRANPILEAFGNSQTVRNNNSSRFGKFIRIEFSRSGQISGA 345
Query: 799 NIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEG--VDNYRFLVNRGITL 972
+I++YLLEKSRV++ ER++HIFYQ+LRG K K + LL ++++ + T+
Sbjct: 346 SIDWYLLEKSRVVKPNLQERNYHIFYQLLRGAEPKLKQKLLLSNLQIEDFAYTREGNDTI 405
Query: 973 PNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEK-KSDQAMLQDDR 1149
V D +E+ S + + IM F++++ I+R V+AVL LGN+ +E ++DQA L D
Sbjct: 406 AGVSDEKEWDSLLEAFHIMNFSEEDQMCILRTVAAVLHLGNITIVKESLRADQAALSRDA 465
Query: 1150 V--IQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFK 1323
+ + K C LLG+ K L P++K GRE+V K Q EQ A++A+AK YER F
Sbjct: 466 LDSVHKACQLLGIETEPFVKGLLHPKVKAGREWVEKVQTPEQVRLALDALAKGIYERGFG 525
Query: 1324 WLVTRINKSLDRTHRQG--ASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMF 1497
LV RIN L+R G + FIG+LDIAGFEIF NSFEQ+CINYTNEKLQQ FN+ MF
Sbjct: 526 DLVNRINSRLERNTVTGEDSYFIGVLDIAGFEIFQNNSFEQLCINYTNEKLQQFFNHHMF 585
Query: 1498 ILEQEEYQREGIEWDFIDFGLDLQPTIDLIE--KPMGVLALLDEECLFPKANDKSFVEKL 1671
+LEQEEY RE IEW FIDFG DLQPTIDLIE P+G+ + LDE+C+ PKA DKSF EKL
Sbjct: 586 VLEQEEYAREQIEWQFIDFGKDLQPTIDLIEVTNPIGIFSCLDEDCVMPKATDKSFTEKL 645
Query: 1672 QKT-HNKHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDP 1848
K K+ R + F + HYA V+YS D WL KN DPLN+N+ L+ +S D
Sbjct: 646 HSLWDTKSTKYRA--SRLRQGFILTHYAAEVEYSTDGWLEKNKDPLNDNITRLLASSQDN 703
Query: 1849 FVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVR 2028
+A ++ D C R +KG+FRTV+Q HKEQL+ LM L +T PHFVR
Sbjct: 704 HIAALFSD------CGNADEVDHPRSRVKKGLFRTVAQRHKEQLSSLMNQLHSTHPHFVR 757
Query: 2029 CIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIP 2208
CIIPNH+K+ +N+ LVL+QLRCNGVLEGIRI R GFPNR+ F EFR RYE+L D +P
Sbjct: 758 CIIPNHKKRPKMLNAPLVLDQLRCNGVLEGIRIARTGFPNRLSFNEFRQRYEVLCRD-MP 816
Query: 2209 KNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQC 2388
K+++DG+ + R M+ L +D +R+G++KVFFR GVLA LEE+RD + ++ FQ+
Sbjct: 817 KSYMDGQSAARIMLQKLALDKAWFRVGRTKVFFRAGVLAELEEKRDELIRTIMTRFQSVA 876
Query: 2389 RGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAK 2568
RGF+ RR+ N AYL+++ WWRLF+++KPLL TRT E++ +
Sbjct: 877 RGFVQRRISNKRLYRAEATHIIQHNFRAYLEMKANPWWRLFSRMKPLLGETRTAQEVKRR 936
Query: 2569 DDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRN 2748
D++++ + ++ + + + ++ E++ + +E IQ+ L+ E + + ++I RLQ R
Sbjct: 937 DEKIKQLETKMKQDQSERQKVEEERRRAEIEIQRIQQTLESERALALDKEEIFKRLQDRE 996
Query: 2749 QEL-EYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNV 2925
EL E + + D+ + ++ E KT +
Sbjct: 997 VELSEKLAGAIADQENLEDQLDELILAKKKTDEE------------------LDLRKTQL 1038
Query: 2926 DQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQL 3105
+Q ++ + +L D E++ + EN +
Sbjct: 1039 EQAGEIIQRLEAERKE------------------MQQKLEDLEQKLLEAQSSASETENHM 1080
Query: 3106 HELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQL 3285
EL Q++ K+L + HL+ K K+++L +L+K D++L +L
Sbjct: 1081 RELGQEV---------------KML------QSHLSLKERKLQDLEAKLLKTDQDLDVKL 1119
Query: 3286 TRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVL 3465
+ +E + + ++++ +DE R T R+ ++ L K
Sbjct: 1120 AKTSKE------LDRSKKEVKDLLDENR---------------TIRQQISDLSKT----- 1153
Query: 3466 DKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK-IEEQKAKFSRQVEELHDQIEQH 3642
+T ++++ RK+ E+ + + +H E K ++ +K+ S + + + +++ +
Sbjct: 1154 -----STSYEEMLRRKESELTVLRN--DAKKHAEEKKQLDVEKSNLSTRHDNMQNKLREL 1206
Query: 3643 KKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHK 3822
+ Q + ++ Q ++E AD+ + + + A+ + RK+ E + +++ L ++
Sbjct: 1207 QAQVDAMVSEKIQLEREAADVQKLLQAKISEDAEAGESRKLLEQQIQDLKNQLFQAQAD- 1265
Query: 3823 RTLIDQLERSRDELDHLNRVR-EEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIAN 3999
+ + +SRD++ L + E + F ++ T T ++A
Sbjct: 1266 ---LSRERQSRDDVQMLAEHKLAELKDKFESLNEAKITIEKEMYIQQDSLRRATEARVAA 1322
Query: 4000 INRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKK 4179
++L+ E L D AE R E E+ A + Q+LE +RK
Sbjct: 1323 EQSRKELQQELIKLRDRFTAAEDARLRAEAEMEQA----------LVKQTTQRLESIRK- 1371
Query: 4180 NLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQ 4359
++++ Q +LEE E + R+ +Q+L ++ E E+ R H D K + + E
Sbjct: 1372 ---ELDNTQHRLEEVEAERSRLAAR----EQQLMNAIAESESFRIRH-DQHKERLERELV 1423
Query: 4360 MAEERVAV-------------QKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESD 4500
+ R+ QK L + S+ + RV +L E K LEE +
Sbjct: 1424 TLKGRLTASENDNRALLTKIQQKNLDIARSNSKASESQRLRVATLQKE----KAKLEEEN 1479
Query: 4501 RVR-----------RSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELE 4647
+ SL+++ + + +D V+ KA R+ E + +Q+ E
Sbjct: 1480 KALSRQLGDQQLSITSLEKQKEKLALSVEDLNHEVNREHKASRNAERAASTASIQLAEAN 1539
Query: 4648 DNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGK 4827
NL+ R + + + L+S D SNK+++ ++ L +I + E + + K
Sbjct: 1540 RNLETERQLRTQAQANTRKLQSALDS--SNKEIDDLHRQLMLFHKIVEPEADPSADSWDK 1597
Query: 4828 -SGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEE--ARQAKE 4998
+S + + + L+ QL+V+ +E+Y + E +E AR +
Sbjct: 1598 IQPDLSRKVDLAQLVETLQSQLQVS---EEKYNRAEAQLAEMRRRHGEEMKELDARYSSS 1654
Query: 4999 DIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKR 5178
ALL E D+ A LR+ +E + A+K S+ R
Sbjct: 1655 K-RALLEEIDQNEVAHNRTPNHLRKNSETAI-AKKFGAPTTPNRRLNINDNSNDSARSDR 1712
Query: 5179 RLEA----KIAQXXXXXXXXQSNCELAIDKQRKAQVQL------EQITTDLSMERTLNQK 5328
++ K Q+ +++ + + Q QL + I D S Q
Sbjct: 1713 TVDTVGYQKRMDLAAEIEELQNKLQMSEMQNKHLQDQLARSVPPKDIWQDDSPSIRRMQL 1772
Query: 5329 TEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANR 5508
E E L D K++ LE S + + L D +N + Q + + R
Sbjct: 1773 LERENGRLHEQLDDSSKKVSALERSIHSGELSLRDVQAKSHEELYDLINSQEQSRRSLLR 1832
Query: 5509 AARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRER 5673
+ D QFE KRA + L + + + L Q +D +SR +
Sbjct: 1833 VHNETVAEITDAKAQFEKLKRAKAALEVELRDACSEAQEL--QAAREQDALSRNQ 1885
Score = 153 bits (386), Expect = 6e-35
Identities = 180/938 (19%), Positives = 393/938 (41%), Gaps = 48/938 (5%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELED-----SKDHLAEKMGK--VE 3234
K K +LE + L + L ++ + LE+ K KL +ED +++H A + +
Sbjct: 1470 KEKAKLEEENKALSRQLGDQQLSITSLEKQKEKLALSVEDLNHEVNREHKASRNAERAAS 1529
Query: 3235 ELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDEL-REDMETERNARNKAE 3411
+ QL + + L+ + + AN +Q + ID+L R+ M + +A+
Sbjct: 1530 TASIQLAEANRNLETERQLRTQAQANTRKLQSALDSSNKEIDDLHRQLMLFHKIVEPEAD 1589
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSR---KDEEVNATKRAIEQIQHTMEGKIE 3582
+ +K++ D+ KVD A +++ L S+ +E+ N + + +++ +++
Sbjct: 1590 PS----ADSWDKIQPDLSRKVDLAQLVETLQSQLQVSEEKYNRAEAQLAEMRRRHGEEMK 1645
Query: 3583 EQKAKFSRQVEELHDQIEQ----HKKQRSQLEKQQNQA----------DQERADMAQEIA 3720
E A++S L ++I+Q H + + L K A R ++
Sbjct: 1646 ELDARYSSSKRALLEEIDQNEVAHNRTPNHLRKNSETAIAKKFGAPTTPNRRLNINDNSN 1705
Query: 3721 LLQASRADID----KKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVRE 3888
S +D +KR A + E+Q L S+ + L DQL RS D + +
Sbjct: 1706 DSARSDRTVDTVGYQKRMDLAAEIEELQNKLQMSEMQNKHLQDQLARSVPPKD----IWQ 1761
Query: 3889 EEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEG 4068
++ +I R + LE E L ++ +++
Sbjct: 1762 DDS--------------------------------PSIRRMQLLERENGRLHEQLDDSSK 1789
Query: 4069 LRAHLEKEIHAARQGAGEARRKAEES----VNQQLEELRKKNLRDVEHLQKQLEESEVAK 4236
+ LE+ IH+ + + K+ E +N Q E+ R+ LR ++ +++
Sbjct: 1790 KVSALERSIHSGELSLRDVQAKSHEELYDLINSQ-EQSRRSLLRVHNETVAEITDAKAQF 1848
Query: 4237 ERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERV---AVQKALLDRD 4407
E++ ++K ++ EL D+ E + ++A+ + + + ++ ++ A D
Sbjct: 1849 EKLKRAKAALEVELRDACSEAQELQAAREQDALSRNQLLQEFSDLQIRLDAETSKSADLA 1908
Query: 4408 AMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDS----ISNKDDFGKNVH 4575
A + R S L + +I +++ ++ +E +D+ ++ + + +
Sbjct: 1909 ASLSLYKSRADEYFSKLEQAEITLLKASRAEQFAKAQAKETEDNCAQIMAERKEMEAIID 1968
Query: 4576 ELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAE 4755
+L++ +SLEA + D Q EL+ LQ A+ RL+ + +++ I +K+ E
Sbjct: 1969 DLQRQTQSLEARMED---QAAELQGALQ----AKQRLQNELEDYRNQRAIDIEDKETSME 2021
Query: 4756 EKRRGLLKQIRDLENELENEKR----GKSGAVSHRKKIENQIGELEQQLEVANRLKEEYX 4923
+ R+ ++I L NELE E+ G++ A R+++E+ + + ++ ++ +E
Sbjct: 2022 QTRQKYQREITTLNNELEMEREKVLNGRTEASRLREELEDLRSKWDNEVLNSSTWAKEKS 2081
Query: 4924 XXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRA----VEAEREQLREANEGLM 5091
A+ + +LL + R R V AER+ L + + ++
Sbjct: 2082 RMEVMLQDVTTSRDEAVNAHNDAQARVVSLLSQV-RSLRTSIDDVTAERDMLHKEKK-ML 2139
Query: 5092 QARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQ 5271
+AR AKG S ++ ++ + + A+ K R+A+
Sbjct: 2140 EAR---LTEAGERLEDLAKGESPSMRNAASMDRELLELKAKLAQQEDLSLAAVGKMRRAE 2196
Query: 5272 VQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKV 5451
++ +++ ER + +K +LE+ ++ + + +LE+ + S + L ++
Sbjct: 2197 ALATEMQKEVTAEREATAQLFKDKAALEKQLKEAQLRCVDLETKSYSSGSQDIRFLHKRI 2256
Query: 5452 QYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLR 5631
+ LE L + + + R+ R +++ + D Q E ++ N Q +E + + K L
Sbjct: 2257 KELETHLEEQEAKNNSEQRSLRNVDRTVKDLQSQIERREKMNAQLEEEVNRGREKVERLL 2316
Query: 5632 RQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
+ +DE + S + + R +RE + + + +L REL
Sbjct: 2317 KNIDELQQSESDSQLQARRAERELREEREKSLRLEREL 2354
Score = 57.4 bits (137), Expect = 4e-06
Identities = 77/383 (20%), Positives = 153/383 (39%), Gaps = 24/383 (6%)
Frame = +1
Query: 3043 LDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKM 3222
+D E++ + + + + ++ L +L ER+ +L ELED + ++
Sbjct: 2011 IDIEDKETSMEQTRQKYQREITTLNNELEMEREKVLNGRTEASRLREELEDLRSKWDNEV 2070
Query: 3223 GKVEELNNQLMKRDEELQHQLTRYDE-------ESANVTLMQKQMRDMQTTIDELREDME 3381
+ + + LQ T DE A V + Q+R ++T+ID++ + +
Sbjct: 2071 LNSSTWAKEKSRMEVMLQDVTTSRDEAVNAHNDAQARVVSLLSQVRSLRTSIDDVTAERD 2130
Query: 3382 TERNARNKAEMTRREVVAQLEKV-KGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQ 3558
+ E E +LE + KG+ + A+M ++L+ E+ A E +
Sbjct: 2131 MLHKEKKMLEARLTEAGERLEDLAKGESPSMRNAASMDRELL-----ELKAKLAQQEDLS 2185
Query: 3559 HTMEGKIEEQKA---KFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADM-------- 3705
GK+ +A + ++V + Q K ++ LEKQ +A D+
Sbjct: 2186 LAAVGKMRRAEALATEMQKEVTAEREATAQLFKDKAALEKQLKEAQLRCVDLETKSYSSG 2245
Query: 3706 AQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDEL-----DH 3870
+Q+I L +++ + EA Q +L D + L Q+ER R+++ +
Sbjct: 2246 SQDIRFLHKRIKELETHLEEQEAKNNSEQRSLRNVDRTVKDLQSQIER-REKMNAQLEEE 2304
Query: 3871 LNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDE 4050
+NR RE+ E N+ + + ++ R+L K AL E
Sbjct: 2305 VNRGREKVERLLKNIDELQQSESDSQLQARRAERELREEREKSLRLERELNGWK-ALRVE 2363
Query: 4051 KEEAEGLRAHLEKEIHAARQGAG 4119
+ + R+H+ +R+G+G
Sbjct: 2364 RGGSAIARSHVAFSDAGSRKGSG 2386
>gi|46128683|ref|XP_388895.1| hypothetical protein FG08719.1
[Gibberella zeae PH-1]
gi|42549573|gb|EAA72416.1| hypothetical protein FG08719.1 [Gibberella
zeae PH-1]
Length = 2398
Score = 887 bits (2292), Expect = 0.0
Identities = 642/1974 (32%), Positives = 994/1974 (49%), Gaps = 104/1974 (5%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
++ W+ D F+ G I E + L+ D Q + + V K NP KFDK DM+E
Sbjct: 118 KRYVWLKDPQTAFVRGWIVEEKDGNQLLVQCDDGTQREVDAESVDKVNPAKFDKANDMAE 177
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LT+LNEASV+HNL RY + LIYTYSGLF V +NPY +PIY+ D I ++G+ R + P
Sbjct: 178 LTHLNEASVVHNLHMRYQTDLIYTYSGLFLVTVNPYATIPIYNNDYINMYRGRSREDTKP 237
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIFA+AD A+R++++E ++QSIL TGESGAGKTENTKKVIQYLA VA A + ++ AQ
Sbjct: 238 HIFAMADEAFRNLVEEGKNQSILVTGESGAGKTENTKKVIQYLAAVAQA--DSTIKNKAQ 295
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
+ L Q+L+ANPILEAFGN++TV+N+NSSRFGKFIRI F +G I G
Sbjct: 296 HS------------SLSEQILRANPILEAFGNAQTVRNNNSSRFGKFIRIEFTRNGAICG 343
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRFLVNRG--IT 969
A I++YLLEKSRV+ Q ER++HIFYQ+L G S+ K E+LL + F+ R +
Sbjct: 344 AYIDWYLLEKSRVVHINQHERNYHIFYQLLTGASSSLKREFLLNDLTVKDFVYTRDGHDS 403
Query: 970 LPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKK-SDQAMLQDD 1146
+ V D +E+ S + + +MGF+DDE SI+R V+AVL LGN+ +E + +DQA L D
Sbjct: 404 IVGVSDPREWASLMEAFNVMGFSDDEQKSILRTVAAVLHLGNINVVKESRTADQARLAPD 463
Query: 1147 RVIQ--KVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLF 1320
Q KVC LLG+P+ + L P++K GRE+V K Q EQ +++A++K YER F
Sbjct: 464 AKAQAAKVCKLLGVPLEPFMRGLLHPKVKAGREWVEKVQTPEQVRLSLDALSKGIYERGF 523
Query: 1321 KWLVTRINKSLDRTHR--QGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTM 1494
LVTRIN+ LDRT + FIG+LDIAGFEIF+ NSFEQ+CINYTNEKLQQ FN+ M
Sbjct: 524 GDLVTRINRQLDRTGMGLDDSHFIGVLDIAGFEIFEQNSFEQLCINYTNEKLQQFFNHHM 583
Query: 1495 FILEQEEYQREGIEWDFIDFGLDLQPTIDLIE--KPMGVLALLDEECLFPKANDKSFVEK 1668
F+LEQEEY RE IEW FIDFG DLQPTIDLIE P+GV + LDE+C+ PKA DKSF EK
Sbjct: 584 FVLEQEEYAREQIEWKFIDFGRDLQPTIDLIELSNPIGVFSCLDEDCVMPKATDKSFTEK 643
Query: 1669 LQKTHNKHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDP 1848
L +K P R F + HYA V+YS + WL KN DPLN+N+ L+ ST+
Sbjct: 644 LNSLWDKKSTKYRPS-RLGQGFILTHYAAEVEYSTEGWLEKNKDPLNDNITRLLAASTNE 702
Query: 1849 FVAGIWKDAEFAGICAAEMNETAFG-MRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFV 2025
VA ++ D CA + A G R ++G+FRTV+Q HKE L LM+ L T PHFV
Sbjct: 703 HVASLFSD------CAESEEDRATGRSRVKRGLFRTVAQKHKEHLHSLMSQLHLTHPHFV 756
Query: 2026 RCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVI 2205
RCI+PNH+KK + N+ LVL+QLRCNGVLEGIRI R GFPNR+PF EFR RYE+L + +
Sbjct: 757 RCILPNHKKKPKEFNNLLVLDQLRCNGVLEGIRIARTGFPNRLPFAEFRQRYEVLCQN-M 815
Query: 2206 PKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQ 2385
PK +++G+ + M+ L +D +LYR+G +KVFFR GVLA LEE+RD +T ++ FQ+
Sbjct: 816 PKGYLEGQAAASLMLEKLGLDRSLYRVGLTKVFFRAGVLAELEEQRDALITQIMSRFQSV 875
Query: 2386 CRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRA 2565
RGF+ RR N YL L WW+L K+KPLL TRT E++
Sbjct: 876 ARGFVQRRAAYKRLFRTEATRIIQRNFNVYLDLAENPWWQLIVKMKPLLGTTRTATEVKR 935
Query: 2566 KD-------DELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDI 2724
+D D+++ E LK+E + R E IQ+ L+ E + + ++I
Sbjct: 936 RDAMIKELNDKMQVESENRLKLEEERRNCH-------AEMVRIQQTLESERALALDKEEI 988
Query: 2725 RGRLQTRNQELEYIVN---DMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXX 2895
RLQ R ELE + + ++RL + +ET R
Sbjct: 989 FKRLQLREAELEEKLAGAIEDQERLEDELDDLLNAKNRAERDVETFR---SQLEQAATLI 1045
Query: 2896 XXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGV 3075
+K + L +QL E +A+
Sbjct: 1046 AKLEEEKNGLSTKIIELEKSITEMTQKQAERSEQEVLLQDEIKMLQSQLAVKERKAQD-- 1103
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQH-KRKLLAELEDSKDHLAEKMGKVEELNNQL 3252
LEN+L +L+QDL EL+ H ++ L ++ + L+++ +++ N+L
Sbjct: 1104 -----LENKLVKLDQDL--------ELKLHIAQRDLQAMKLRETQLSQENDDIQQQLNEL 1150
Query: 3253 MKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDM--ETERNARNKAEMTRRE 3426
K E + + + + E + + K + ++++ R+ + E E+NA E
Sbjct: 1151 SKTATEYEDLVRQKESELSLLRTDNKNFESERQSLEDQRKSLTAEKEKNAEKYHEAQAEL 1210
Query: 3427 VV-----AQLEKVKGDVLDKVDEATMLQDLMSRKDEEV--NATKRAIEQIQHTMEGKIEE 3585
V AQLE+ D + + EA + +D + ++ +V + TK +++ T E
Sbjct: 1211 VAMKSRQAQLEREAEDAKNLL-EARLSEDAQADQNRQVLESQTKDLKDELYKTQMELSRE 1269
Query: 3586 QKAKFSRQV------EELHDQIEQHKKQRSQLEKQ--------------QNQADQERADM 3705
++++ Q+ +EL D+ ++ + + +EK+ + A++ER +
Sbjct: 1270 RQSRDDVQLLGEHRYQELKDEFDRVNESKIIIEKEMYAQQDTLRRTLEARTTAEKERDEA 1329
Query: 3706 AQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVR 3885
QEI L+ ++ ++ R E E QA+ A D + +L L+ +++ L +
Sbjct: 1330 RQEIRRLRVAKTQAEEARMQAEV-AGERQASKAAQD-RENSLRKDLDAAQERLHWFDGEC 1387
Query: 3886 EEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAE 4065
+ H ++ + + + R +R E++ ALL+ K + +
Sbjct: 1388 AKLNHQIEDLNKLILESGEFGLKNDQAKERLERELTTVKSRLTASENDNRALLN-KLQQK 1446
Query: 4066 GLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERI 4245
GL EI + A EA R +S+ ++ L ++N + L KQL +S++A +
Sbjct: 1447 GL------EIARSSSRASEASRGQIQSLQREKARLEEQNTK----LNKQLGDSQLAIASL 1496
Query: 4246 LQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDR------- 4404
+ +K+Q LED S E+ S R++EK F +Q+AE ++ R
Sbjct: 1497 EKRAEKLQLNLEDLSHEVAREVKSSRNAEKATSTFTAQLAEANRTIESERQLRTQAQTTV 1556
Query: 4405 -------DAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFG 4563
D+ +E+ + ++L +L VD +SD + + D + ++
Sbjct: 1557 RTLQSSVDSRDKEINELRAQMLEVLRTVDPEVHIPPQSDGTDEKVLIQNFDLVRKVEELQ 1616
Query: 4564 KNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAE----DARLRLEVTNQALKSESDRAI 4731
+N+ A+ + E +L +MR E ++ E +A + T + ++ A+
Sbjct: 1617 QNLRVQTAARTNAENQLTEMRASRNESPTRPKLEEIQLNEAPFQGSPTQR--RTTKLHAL 1674
Query: 4732 SNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLK 4911
++ + +R ++ L++ +++ + ++R ++ ++ EL+ QL++ ++
Sbjct: 1675 NHSNTSTPTRR---FQEPDHLQDSTRSDRTIDTLNFNNRMDLKAEVEELQNQLQL-KEMQ 1730
Query: 4912 EEYXXXXXXXXXXXXEYQIECEEAR--QAKEDIAALLRE-ADRKFRAVEAEREQLREANE 5082
+ E E R Q E + L E D + V A +R
Sbjct: 1731 NRHLQSQIDRGTPVPENHDESPSLRRIQKLEMVNTRLHEMLDDSNKKVSALERTIRSGQL 1790
Query: 5083 GLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQR 5262
L + + + + +R L + + E +
Sbjct: 1791 SLRDVQTRTHEEILEVLNSQ-------EDSRRALVHSHKDAVAELTDIKGHFERLRHDRA 1843
Query: 5263 KAQVQLEQITTDLSMERTLNQKTEAEKQ--------------------------SLE--R 5358
KA+V+L + +DL E TL ++ EA+ + SLE R
Sbjct: 1844 KAEVELRDVKSDLE-EMTLAREQEAQSRNQLLQEFADLQIRLDAETSKFIDVASSLEMYR 1902
Query: 5359 SNRD-YKAKITELESGAQSRARAQM----AALEAKVQYLEDQLNVEGQEKTAANRAARRL 5523
S D Y +K+ + E +RA+ A EA+ Y+E + E ++ A +R
Sbjct: 1903 SRADEYFSKLEQAEIAVLKASRAEQFARSQAREAEDTYVE--IMAEREKMDATIEDLQRQ 1960
Query: 5524 EKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHR 5685
+ L + + + A QAK+ L+ RN +R +D + E S E+T+ +
Sbjct: 1961 NQHLEEKVEDISTDLAAATQAKKRLQHELEDYRN-QRAIDIEDKESSMEQTRKK 2013
Score = 154 bits (389), Expect = 2e-35
Identities = 205/942 (21%), Positives = 378/942 (39%), Gaps = 66/942 (7%)
Frame = +1
Query: 3118 QDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYD 3297
Q L RE K+ LE+ KL +L DS+ +A + E+L L E+L H++ R
Sbjct: 1466 QSLQRE---KARLEEQNTKLNKQLGDSQLAIASLEKRAEKLQLNL----EDLSHEVAREV 1518
Query: 3298 EESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRR--------------EVVA 3435
+ S N +K + E +E+ER R +A+ T R E+ A
Sbjct: 1519 KSSRNA---EKATSTFTAQLAEANRTIESERQLRTQAQTTVRTLQSSVDSRDKEINELRA 1575
Query: 3436 QLEKVKGDV---------LDKVDEATMLQDL-MSRKDEEVNATKRAIEQIQHTMEGKIEE 3585
Q+ +V V D DE ++Q+ + RK EE+ R + E ++ E
Sbjct: 1576 QMLEVLRTVDPEVHIPPQSDGTDEKVLIQNFDLVRKVEELQQNLRVQTAARTNAENQLTE 1635
Query: 3586 QKAKFSR----------QVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQAS 3735
+A + Q+ E Q +++ ++L + QE LQ S
Sbjct: 1636 MRASRNESPTRPKLEEIQLNEAPFQGSPTQRRTTKLHALNHSNTSTPTRRFQEPDHLQDS 1695
Query: 3736 -RAD--ID----KKRKIHEAHLMEIQANLAESDEHKRTLIDQLER------SRDELDHLN 3876
R+D ID R +A + E+Q L + R L Q++R + DE L
Sbjct: 1696 TRSDRTIDTLNFNNRMDLKAEVEELQNQLQLKEMQNRHLQSQIDRGTPVPENHDESPSLR 1755
Query: 3877 RVREEEE-----HAFANMQRRLATAXXXXXXXXXXXXXX--TRLKIANINRARQLEDEKN 4035
R+++ E H + + +A TR + ED +
Sbjct: 1756 RIQKLEMVNTRLHEMLDDSNKKVSALERTIRSGQLSLRDVQTRTHEEILEVLNSQEDSRR 1815
Query: 4036 ALL----DEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHL 4203
AL+ D E ++ H E+ H R KAE LRDV+
Sbjct: 1816 ALVHSHKDAVAELTDIKGHFERLRHD--------RAKAEVE------------LRDVK-- 1853
Query: 4204 QKQLEESEVAKERILQSKKKIQQELEDSSMELE-------NVRASHRDSEKRQKKFESQM 4362
LEE +A+E+ QS+ ++ QE D + L+ +V +S R ++ S++
Sbjct: 1854 -SDLEEMTLAREQEAQSRNQLLQEFADLQIRLDAETSKFIDVASSLEMYRSRADEYFSKL 1912
Query: 4363 AEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSI 4542
+ +AV KA + R+ E + ++ E + M +E+ R + L+++++D
Sbjct: 1913 EQAEIAVLKASRAEQFARSQAREAEDTYVEIMAEREKMDATIEDLQRQNQHLEEKVED-- 1970
Query: 4543 SNKDDFGKNVHELEKAKRSLEAELNDMRVQME-ELEDNLQIAEDARLRLEVTNQALKSES 4719
++ +AK+ L+ EL D R Q ++ED E R + + L +E
Sbjct: 1971 -----ISTDLAAATQAKKRLQHELEDYRNQRAIDIEDKESSMEQTRKKYQAEFATLTNEL 2025
Query: 4720 DRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVA 4899
D A K + E R L +++ +L ++ ++E S + ++E+ + ++ + A
Sbjct: 2026 DLAREEKLFKQAEIAR-LREELDELRSKWDDEVLNSSTWCKEKARLESTLADVASSRDEA 2084
Query: 4900 NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREAN 5079
E + R + ++IAA R+ R VEA E+ +
Sbjct: 2085 VNAHNEAQGKVVTLLS-------QVRSLRSSVDEIAAERDHLIREKRNVEARLEEAKSGL 2137
Query: 5080 EGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQ 5259
E L+ KG S ++ +I + A++K
Sbjct: 2138 EDLV------------------KGESPSLRNAANMDKEILDLKSNLAQQEDIAAAAVEKM 2179
Query: 5260 RKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAAL 5439
R+A+ + ++ D+ +ER + K + +K SLE+ + + K+ +LE+ S A + L
Sbjct: 2180 RRAESLVAEVQKDVMVERENSIKLQQQKASLEKVLNEAQLKLVDLETKGYSSASQDVKFL 2239
Query: 5440 EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKN 5619
++Q LE QL + E++ + R+ R +++ + D Q + + + N Q + + + K
Sbjct: 2240 HKRIQELESQLEDQETERSKSQRSVRNVDRIVKDMQGQIDRKDKQNMQLSDDVSRMRDKV 2299
Query: 5620 RNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
L + ++E + S + R +RE + + ++ REL
Sbjct: 2300 EKLLKTIEELQSSESNNQLSARRAERELREEKERAIRMEREL 2341
Score = 104 bits (259), Expect = 3e-20
Identities = 214/1099 (19%), Positives = 421/1099 (37%), Gaps = 32/1099 (2%)
Frame = +1
Query: 2539 TRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELD 2718
T +D +R K+ EL + E + + E + + E+ ++ ++ E AEL
Sbjct: 1155 TEYEDLVRQKESELSLLRTDNKNFESERQSLEDQRKSLTAEK---EKNAEKYHEAQAELV 1211
Query: 2719 DIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXX 2898
++ R +E E N + RLS Q + ++D
Sbjct: 1212 AMKSRQAQLEREAEDAKNLLEARLSEDAQADQNRQVLE-SQTKDLKDELYKTQMELSR-- 1268
Query: 2899 XXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVK 3078
++ + D +D +D + ++ ++ + ++
Sbjct: 1269 ----ERQSRDDVQLLGEHRYQELKDEFDRVNESKII-------IEKEMYAQQDTLRRTLE 1317
Query: 3079 AKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMK 3258
A+ E + E Q++ R R K++ E+ + + E + + A K + E N L K
Sbjct: 1318 ARTTAEKERDEARQEIRRLRVAKTQAEEARM----QAEVAGERQASKAAQDRE--NSLRK 1371
Query: 3259 RDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQ 3438
+ Q +L +D E A + Q+ D+ I E E A+ + E V ++
Sbjct: 1372 DLDAAQERLHWFDGECAK---LNHQIEDLNKLILESGEFGLKNDQAKERLERELTTVKSR 1428
Query: 3439 LEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEE 3618
L + D +L L + E ++ RA E + ++ ++ +KA+ Q +
Sbjct: 1429 LTASEND------NRALLNKLQQKGLEIARSSSRASEASRGQIQS-LQREKARLEEQNTK 1481
Query: 3619 LHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQAN 3798
L+ Q+ + + LEK+ + D++ E+A S + +K A L E
Sbjct: 1482 LNKQLGDSQLAIASLEKRAEKLQLNLEDLSHEVAREVKSSRNAEKATSTFTAQLAEANRT 1541
Query: 3799 LAESDEHKR----TLIDQLERSRDELD-HLNRVREEEEHAFANMQRRLATAXXXXXXXXX 3963
+ ES+ R T + L+ S D D +N +R A M L T
Sbjct: 1542 I-ESERQLRTQAQTTVRTLQSSVDSRDKEINELR-------AQMLEVLRTVDPEVHIPPQ 1593
Query: 3964 XXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEE 4143
++ I N + R++E E + LR +A Q + E
Sbjct: 1594 SDGTDEKVLIQNFDLVRKVE----------ELQQNLRVQTAARTNAENQLTEMRASRNES 1643
Query: 4144 SVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASH- 4320
+LEE+ QL E+ + K+ L S+ R
Sbjct: 1644 PTRPKLEEI-------------QLNEAPFQGSPTQRRTTKL-HALNHSNTSTPTRRFQEP 1689
Query: 4321 ---RDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL-SLLNEVDIMKEHL 4488
+DS + + ++ R+ + KA ++ +L++ + R L S ++ + E+
Sbjct: 1690 DHLQDSTRSDRTIDTLNFNNRMDL-KAEVEELQNQLQLKEMQNRHLQSQIDRGTPVPENH 1748
Query: 4489 EESDRVRRSLQQELQDSISNK--DDFGKNVHELEKAKRSLEAELNDMRVQM-EELEDNLQ 4659
+ES +RR + E+ ++ ++ DD K V LE+ RS + L D++ + EE+ + L
Sbjct: 1749 DESPSLRRIQKLEMVNTRLHEMLDDSNKKVSALERTIRSGQLSLRDVQTRTHEEILEVLN 1808
Query: 4660 IAEDARLRLEVTNQALKSESDRAISNKDVEA--EEKRRGLLK---QIRDLENELENEKRG 4824
ED+R L + S D D++ E R K ++RD++++LE
Sbjct: 1809 SQEDSRRAL------VHSHKDAVAELTDIKGHFERLRHDRAKAEVELRDVKSDLEEMTLA 1862
Query: 4825 KSGAVSHRKKIENQIGELEQQL--------EVANRLKEEYXXXXXXXXXXXXEYQIECEE 4980
+ R ++ + +L+ +L +VA+ L E Y + +I +
Sbjct: 1863 REQEAQSRNQLLQEFADLQIRLDAETSKFIDVASSL-EMYRSRADEYFSKLEQAEIAVLK 1921
Query: 4981 ARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGI 5160
A +A++ + REA+ + + AERE++ E L +
Sbjct: 1922 ASRAEQFARSQAREAEDTYVEIMAEREKMDATIEDLQR---------------------- 1959
Query: 5161 SSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAE 5340
+ + LE K+ + +LA Q K ++Q E D +R ++ E +
Sbjct: 1960 ---QNQHLEEKVEDI---------STDLAAATQAKKRLQHE--LEDYRNQRAID--IEDK 2003
Query: 5341 KQSLERSNRDYKAKI----TELESGAQSR--ARAQMAALEAKVQYLEDQLNVEGQEKTAA 5502
+ S+E++ + Y+A+ EL+ + + +A++A L ++ L + + E +
Sbjct: 2004 ESSMEQTRKKYQAEFATLTNELDLAREEKLFKQAEIARLREELDELRSKWDDEVLNSSTW 2063
Query: 5503 NRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKH 5682
+ RLE L D ++ A+ +A+ + + R+LR +DE E +
Sbjct: 2064 CKEKARLESTLADVASSRDEAVNAHNEAQGKVVTLLSQVRSLRSSVDEIAAERDHLIREK 2123
Query: 5683 RNVQREADDLLDANEQLTR 5739
RNV+ ++ E L +
Sbjct: 2124 RNVEARLEEAKSGLEDLVK 2142
>gi|38100724|gb|EAA47817.1| hypothetical protein MG03060.4
[Magnaporthe grisea 70-15]
Length = 2403
Score = 880 bits (2275), Expect = 0.0
Identities = 621/2003 (31%), Positives = 990/2003 (49%), Gaps = 124/2003 (6%)
Frame = +1
Query: 76 RKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSE 255
++ W+ D F+ G + E ++ D Q + + V K NP KFDK EDM+E
Sbjct: 113 KRYVWLKDPQTAFVKGWVVEELGAGRILVQCDDGTQREVDSESVDKVNPAKFDKAEDMAE 172
Query: 256 LTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPP 435
LT+LNEASV+HNL RY S LIYTYSGLF V +NPY LPIYS + + +KG+ R + P
Sbjct: 173 LTHLNEASVVHNLHMRYQSDLIYTYSGLFLVTVNPYCPLPIYSNEYVNMYKGRSREDTKP 232
Query: 436 HIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQ 615
HIFA+AD A+R+++ E E+QSIL TGESGAGKTENTKKVIQYLA VA + +Q
Sbjct: 233 HIFAMADHAFRNLVDEGENQSILVTGESGAGKTENTKKVIQYLAAVAHSESPVKAKGQSQ 292
Query: 616 QNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISG 795
+ L Q+L+ANPILEAFGN++TV+N+NSSRFGKFIRI F +G I+G
Sbjct: 293 HS------------NLSAQILRANPILEAFGNAQTVRNNNSSRFGKFIRIEFSKNGSIAG 340
Query: 796 ANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRFLVNR--GIT 969
A I++YLLEKSRV+R +ER++H+FYQ+L+G + K ++L++G+D F R T
Sbjct: 341 AFIDWYLLEKSRVVRINSNERNYHVFYQLLKGADRRMKEDFLIDGMDTEDFAYTRDGNDT 400
Query: 970 LPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKK-SDQAMLQDD 1146
+ V D +E+ + + + +MGF + ++I+R ++AVL LGN+ +E + +DQA L D
Sbjct: 401 ISGVSDREEWETLMEAFHVMGFNGQDQAAILRTIAAVLHLGNINLVKESRAADQARLAPD 460
Query: 1147 --RVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLF 1320
+KVC LLG+P+ + L P++K GRE+V K Q EQ ++A++K YER F
Sbjct: 461 AKSFAEKVCRLLGIPLEPFLQGLLHPKVKAGREWVEKVQTPEQVRLGIDALSKGIYERAF 520
Query: 1321 KWLVTRINKSLDRT--HRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTM 1494
LVTRIN+ LDRT + FIG+LDIAGFEIF+ NSFEQ+CINYTNEKLQQ FN+ M
Sbjct: 521 GDLVTRINRQLDRTGMGMDDSRFIGVLDIAGFEIFEENSFEQLCINYTNEKLQQFFNHHM 580
Query: 1495 FILEQEEYQREGIEWDFIDFGLDLQPTIDLIE--KPMGVLALLDEECLFPKANDKSFVEK 1668
F+LEQEEY RE IEW FIDFG DLQPTIDLIE P+G+ + LDE+ + PKA D +F EK
Sbjct: 581 FVLEQEEYAREQIEWQFIDFGRDLQPTIDLIELPNPIGIFSCLDEDSVMPKATDITFTEK 640
Query: 1669 LQKTHNKHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDP 1848
L +K P R K F + HYA V+YS D WL KN DPLN+NV L+ ST+
Sbjct: 641 LHSLWDKKSNKYRPS-RLKHGFILTHYAAEVEYSTDGWLEKNKDPLNDNVTRLLAASTEN 699
Query: 1849 FVAGIWKDAEFAGICAAEMNETAFGMRSR--KGMFRTVSQLHKEQLTKLMTTLRNTSPHF 2022
VA ++ D AE ++ G+RSR KG+FRTV+Q HKEQL+ LM L +T PHF
Sbjct: 700 HVANLFAD-------CAEQDDEYGGVRSRVKKGLFRTVAQRHKEQLSSLMAQLHSTHPHF 752
Query: 2023 VRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDV 2202
VRCI+PNH+KK N+ LVL+QLRCNGVLEGIRI R GFPNR+ F EFR RYE+L D
Sbjct: 753 VRCILPNHKKKPKMFNNLLVLDQLRCNGVLEGIRIARTGFPNRLSFSEFRQRYEVLCRD- 811
Query: 2203 IPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQA 2382
+PK +++G+ + ++ L +D L+R+G +KVFFR GVLA LEE+RD +T ++ FQ+
Sbjct: 812 MPKGYLEGQAAASIILDKLGLDRGLFRVGLTKVFFRAGVLAELEEQRDALITEIMSRFQS 871
Query: 2383 QCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIR 2562
RGF+ RR+ N YL L + WW+L ++KPLL TRT E++
Sbjct: 872 VARGFMQRRIAYKRLYRAEATRVIQRNLNVYLNLCDDPWWQLLIRMKPLLGATRTATEVK 931
Query: 2563 AKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQT 2742
+D+ +R +++ + E D + E++ E IQ+ L+ E + + ++I RLQ
Sbjct: 932 RRDELIRQLHDKMKQEEMDRQRLEEERRTTHTEMMRIQQTLESERALALDKEEIFKRLQL 991
Query: 2743 RNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTN 2922
R ELE ++ + ++ E V +KT+
Sbjct: 992 REVELEEKLSGAIEDQERLEDQLDSLLDAKKLAEEQVEKYRTQLEQAASLIGKLEEEKTD 1051
Query: 2923 VDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQ 3102
+ L +QL + +A+ LE +
Sbjct: 1052 LGDRLSSLEKEMKEMSQRQSQRSAEEEALQDEIKMLQSQLSLKDRKARD-------LEGK 1104
Query: 3103 LHELEQD----LNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L +++QD L ++ + +++L+AE D++ L++ + + + K++ E
Sbjct: 1105 LLKIDQDAEVKLVAAQKELQTFKSREQRLIAENRDAQQQLSKLSKTSTDYEDLVRKKESE 1164
Query: 3271 L----------------------------QHQLTRYDEESANVTLMQKQMRDMQTTIDEL 3366
L + TR E A ++ ++ Q +Q D+
Sbjct: 1165 LALLRSDNKKYETEHRSFEEQKKTLAAEKEKAATRLREVQAEISALKSQQSQLQREADDA 1224
Query: 3367 REDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSR----KDEEVNAT 3534
++ ++ + +A+ R + ++G + D DE Q +SR +D+ +
Sbjct: 1225 KKLLQARLSEDAQADQNR-------QVLEGQIKDLKDELYKTQMDLSRERQSRDDVLLLG 1277
Query: 3535 KRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQE 3714
+ +++Q E ++ E K +++ D + + + R+ EK++++A E
Sbjct: 1278 EHEYQKLQEEYE-RLNESKITIEKELYAQQDTLRRTMEARATAEKERDEA-------RDE 1329
Query: 3715 IALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEE 3894
I L+ ++ ++ R+ EA +A L + E + +L L+ +++ L +
Sbjct: 1330 IRKLRVAKVQAEEARR--EAENAGERAALKIARERETSLRKDLDAAQERLKWFEDECAKL 1387
Query: 3895 EHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLR 4074
H ++ + + ++ R R E++ ALL+ K + +GL
Sbjct: 1388 NHQVEDLNKLILSSGEFGLKNDQEKERMQRELTTVKGRLMASENDNRALLN-KLQQKGL- 1445
Query: 4075 AHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQS 4254
EI + A EA R +++++ + ++N++ L KQL ++++ + +
Sbjct: 1446 -----EIARSTSRASEASRGQVTALSREKARVEEQNVK----LNKQLGDAQLTIAALEKK 1496
Query: 4255 KKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAE--------------ERVAVQKA 4392
+K+Q LED ++E+ + R++EK F +Q+AE + V+
Sbjct: 1497 AEKLQLNLEDLNLEVSRETKASRNAEKTSSNFTAQLAEANRTIESERQLKTQAQTTVRTL 1556
Query: 4393 LLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNV 4572
D+ +EL + ++LS+L VD D + + I+ D + V
Sbjct: 1557 QTTLDSRDKELVELRAQMLSILKTVDPDALPAIAPDNTKNEM------FIAKNYDLARKV 1610
Query: 4573 HELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNK---- 4740
EL+++ R A Q+ EL + RL N+A + S +K
Sbjct: 1611 EELQQSLRVQTAARQTAENQVAELRAQKHDSPRPRLEEINPNEAPFNVSPTQRKSKINGR 1670
Query: 4741 --DVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVA----- 4899
+ RR + + +++ + ++R+ ++ ++ EL+ QL+++
Sbjct: 1671 HYSTASTPPRRFNGADGDHSHDSVRSDRTADVLSFNNRQDLKTEVEELQNQLQLSEMKNR 1730
Query: 4900 ---NRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAERE--- 5061
++L+ + ++ QA + +L ++ +K A+E
Sbjct: 1731 HLESQLERATPGPDATYGEESPSARRRAQKLEQANSRLQDMLDDSSKKVSALEKTVRTGE 1790
Query: 5062 ------QLREANEGLMQARKQXXXXXXXXXXXRAKGGGISS-----EEKRRLEAKIAQXX 5208
Q R E L Q R ++ ++ R AK+
Sbjct: 1791 LSLRDIQTRSHEEILDLLNSQEESRRSLLLSHRDAVAELTDIKEHFDKMRHDRAKVEVDL 1850
Query: 5209 XXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQS---LERSNRD-YK 5376
+ LA D++ ++ QL Q DL + A+ + L +S D Y
Sbjct: 1851 RDARSELQDISLARDQEAASRSQLLQEFADLQIRLDAETSKLADVTANLHLYKSRADEYF 1910
Query: 5377 AKITELESG----------AQSRAR-----------------AQMAALEAKVQYLEDQLN 5475
+K+ + E A+S+AR A + L+ + Q LE++L
Sbjct: 1911 SKLEQAEIAVLKANRAEQFARSQAREAEDTCAEVMSERQRMDAAVEDLQRQNQRLEEKLE 1970
Query: 5476 VEGQEKTAANRAARRLEKRLNDTTQQ----FEDEKRANEQAKELLEKSNLKNRNLRRQLD 5643
+ AA +A RRL+ L D Q ED++ + EQ + +K + L ++LD
Sbjct: 1971 DLSTDLEAATQAKRRLQHELEDYRAQRANDIEDKESSMEQTR---KKYQAEFATLTKELD 2027
Query: 5644 EAEDEMSRERTKHRNVQREADDL 5712
A +E ++ + ++ E D+L
Sbjct: 2028 LAREERLFKQAEVVRLREELDEL 2050
Score = 132 bits (331), Expect = 1e-28
Identities = 201/975 (20%), Positives = 382/975 (38%), Gaps = 97/975 (9%)
Frame = +1
Query: 3112 LEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTR 3291
L+ D +ER + EL K +L+A D++ L + K E+ + E + Q+T
Sbjct: 1406 LKNDQEKERMQR-ELTTVKGRLMASENDNRALLNKLQQKGLEIARSTSRASEASRGQVTA 1464
Query: 3292 YDEESANV----TLMQKQMRDMQTTI--------------DELREDMETERNARNKAEMT 3417
E A V + KQ+ D Q TI ++L ++ E A AE T
Sbjct: 1465 LSREKARVEEQNVKLNKQLGDAQLTIAALEKKAEKLQLNLEDLNLEVSRETKASRNAEKT 1524
Query: 3418 RREVVAQLEKVKGDVLDKVDEATM-------LQDLMSRKDEEVNATKRAIEQIQHTMEG- 3573
AQL + + + T LQ + +D+E+ + + I T++
Sbjct: 1525 SSNFTAQLAEANRTIESERQLKTQAQTTVRTLQTTLDSRDKELVELRAQMLSILKTVDPD 1584
Query: 3574 ----------KIEEQKAK---FSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMA-- 3708
K E AK +R+VEEL + R E Q + ++ D
Sbjct: 1585 ALPAIAPDNTKNEMFIAKNYDLARKVEELQQSLRVQTAARQTAENQVAELRAQKHDSPRP 1644
Query: 3709 --QEIALLQA--SRADIDKKRKIHEAHLMEIQA-----NLAESDEHKRTLIDQLERSRDE 3861
+EI +A + + +K KI+ H N A+ D ++ + +R+ D
Sbjct: 1645 RLEEINPNEAPFNVSPTQRKSKINGRHYSTASTPPRRFNGADGDHSHDSV--RSDRTADV 1702
Query: 3862 LDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXTRLKIANIN--------RARQ 4017
L NR ++ + +Q +L + T A RA++
Sbjct: 1703 LSFNNR--QDLKTEVEELQNQLQLSEMKNRHLESQLERATPGPDATYGEESPSARRRAQK 1760
Query: 4018 LEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESV----NQQLEELRK--- 4176
LE + L D +++ + LEK + + + ++ E + N Q E R
Sbjct: 1761 LEQANSRLQDMLDDSSKKVSALEKTVRTGELSLRDIQTRSHEEILDLLNSQEESRRSLLL 1820
Query: 4177 ------KNLRDV-EHLQK-----------------QLEESEVAKERILQSKKKIQQELED 4284
L D+ EH K +L++ +A+++ S+ ++ QE D
Sbjct: 1821 SHRDAVAELTDIKEHFDKMRHDRAKVEVDLRDARSELQDISLARDQEAASRSQLLQEFAD 1880
Query: 4285 SSMELE-------NVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETR 4443
+ L+ +V A+ + R ++ S++ + +AV KA + R+ E
Sbjct: 1881 LQIRLDAETSKLADVTANLHLYKSRADEYFSKLEQAEIAVLKANRAEQFARSQAREAEDT 1940
Query: 4444 VLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDM 4623
+++E M +E+ R + L+++L+D ++ +AKR L+ EL D
Sbjct: 1941 CAEVMSERQRMDAAVEDLQRQNQRLEEKLED-------LSTDLEAATQAKRRLQHELEDY 1993
Query: 4624 RVQM-EELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLEN 4800
R Q ++ED E R + + L E D A + + E R L +++ +L +
Sbjct: 1994 RAQRANDIEDKESSMEQTRKKYQAEFATLTKELDLAREERLFKQAEVVR-LREELDELRS 2052
Query: 4801 ELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEE 4980
+ ++E S + ++E + ++ + A E + +E
Sbjct: 2053 KWDDEVLNSSTWSKEKTRLEATLADVVASRDEAVGAHNEAQGKIVNLLSQVRTLRANVDE 2112
Query: 4981 ARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGI 5160
A ++ ALLRE R +E+ +L+EA GL + K G
Sbjct: 2113 ASAERD---ALLREK----RGLES---RLQEAKAGLEELSKA--------------GESP 2148
Query: 5161 SSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAE 5340
S ++ +I + + A++K R+A+ + ++ D++ ER K + E
Sbjct: 2149 SLRNAAGMDKEILELKSSLAHHEDVASAAVEKMRRAEALVAEVQKDMAAERDNAAKLQKE 2208
Query: 5341 KQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARR 5520
K +LE++ + K K+ LE+ A Q+ L +++ +++ + + Q R+ R
Sbjct: 2209 KTALEKALSEEKVKLVNLETKVYPSA-GQVKFLNTRIEEAQEEQHNKSQ------RSVRN 2261
Query: 5521 LEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQRE 5700
+++ + D Q E + + N Q ++ L + K L + +DE + S + R +RE
Sbjct: 2262 VDRTVKDLQSQIERKDKQNGQLQDDLTRMRDKADKLLKTIDELQAADSTAQLNARRAERE 2321
Query: 5701 ADDLLDANEQLTREL 5745
+ + QL REL
Sbjct: 2322 LREEKEKTMQLEREL 2336
Score = 85.5 bits (210), Expect = 1e-14
Identities = 207/1018 (20%), Positives = 380/1018 (36%), Gaps = 160/1018 (15%)
Frame = +1
Query: 3175 LLAELEDSKDHL-AEKMGKVEELNNQLMKRDEELQH----QLTRYDEESANVTLMQKQMR 3339
+LAELE+ +D L E M + + + M+R + + TR + + NV L
Sbjct: 850 VLAELEEQRDALITEIMSRFQSVARGFMQRRIAYKRLYRAEATRVIQRNLNVYLNLCDDP 909
Query: 3340 DMQTTIDELREDMETERNARNKAEMTRR-EVVAQL-EKVKGDVLDKVDEATMLQDLMSRK 3513
Q I ++ + R A E+ RR E++ QL +K+K + +D+ R
Sbjct: 910 WWQLLI-RMKPLLGATRTA---TEVKRRDELIRQLHDKMKQEEMDR-----------QRL 954
Query: 3514 DEEVNATKRAIEQIQHTMEGK--------------------IEEQKAKFSRQVEELHDQI 3633
+EE T + +IQ T+E + +EE+ + E L DQ+
Sbjct: 955 EEERRTTHTEMMRIQQTLESERALALDKEEIFKRLQLREVELEEKLSGAIEDQERLEDQL 1014
Query: 3634 -----------EQHKKQRSQLEKQQN---QADQERADMAQEIALLQASRADIDKKRKIHE 3771
EQ +K R+QLE+ + + ++E+ D+ ++ L+ ++ +++
Sbjct: 1015 DSLLDAKKLAEEQVEKYRTQLEQAASLIGKLEEEKTDLGDRLSSLEKEMKEMSQRQSQRS 1074
Query: 3772 A-------HLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLA 3930
A + +Q+ L+ D R L +L + + + ++E F + ++RL
Sbjct: 1075 AEEEALQDEIKMLQSQLSLKDRKARDLEGKLLKIDQDAEVKLVAAQKELQTFKSREQRLI 1134
Query: 3931 T-------AXXXXXXXXXXXXXXTRLKIANI-----------NRARQLEDEKNALLDEKE 4056
R K + + R E++K L EKE
Sbjct: 1135 AENRDAQQQLSKLSKTSTDYEDLVRKKESELALLRSDNKKYETEHRSFEEQKKTLAAEKE 1194
Query: 4057 EAEGLRAHLEKEIHAARQGAGEARRKAEES---------------VNQQLEELRKKNLRD 4191
+A ++ EI A + + +R+A+++ N+Q+ E + K+L+D
Sbjct: 1195 KAATRLREVQAEISALKSQQSQLQREADDAKKLLQARLSEDAQADQNRQVLEGQIKDLKD 1254
Query: 4192 V----------------------EHLQKQLEESEVAKERILQSKKKIQQELEDSSMELEN 4305
EH ++L+E ER+ +SK I++EL L
Sbjct: 1255 ELYKTQMDLSRERQSRDDVLLLGEHEYQKLQEE---YERLNESKITIEKELYAQQDTLRR 1311
Query: 4306 VRASHRDSEKRQKKFESQMAEERVA-VQKALLDRDAMS-------QELRDRETRVLSLLN 4461
+ +EK + + ++ + RVA VQ R+A + + R+RET SL
Sbjct: 1312 TMEARATAEKERDEARDEIRKLRVAKVQAEEARREAENAGERAALKIARERET---SLRK 1368
Query: 4462 EVDIMKEHLEESDRVRRSLQQELQD---SISNKDDFG-KNVHELEKAKRSLE-------A 4608
++D +E L+ + L +++D I + +FG KN E E+ +R L A
Sbjct: 1369 DLDAAQERLKWFEDECAKLNHQVEDLNKLILSSGEFGLKNDQEKERMQRELTTVKGRLMA 1428
Query: 4609 ELNDMRVQMEELED-NLQIAED---------------ARLRLEVTNQALKSESDRAISNK 4740
ND R + +L+ L+IA +R + V Q +K +
Sbjct: 1429 SENDNRALLNKLQQKGLEIARSTSRASEASRGQVTALSREKARVEEQNVKLNKQLGDAQL 1488
Query: 4741 DVEAEEKRRGLLK-QIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEE 4917
+ A EK+ L+ + DL E+ E + A Q+ E + +E +LK +
Sbjct: 1489 TIAALEKKAEKLQLNLEDLNLEVSRETKASRNAEKTSSNFTAQLAEANRTIESERQLKTQ 1548
Query: 4918 YXXXXXXXXXXXXEYQIECEEAR-QAKEDIAALLREADRKFRAVEAEREQLREANEGLMQ 5094
E E R Q + + +A + E N L
Sbjct: 1549 AQTTVRTLQTTLDSRDKELVELRAQMLSILKTVDPDALPAIAPDNTKNEMFIAKNYDL-- 1606
Query: 5095 ARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAID-KQRKAQ 5271
ARK A+ + + R + + + + QRK++
Sbjct: 1607 ARKVEELQQSLRVQTAARQTAENQVAELRAQKHDSPRPRLEEINPNEAPFNVSPTQRKSK 1666
Query: 5272 VQLEQITTDLSMERTLNQKTEAEKQSLERSNR-----------DYKAKITELESGAQSRA 5418
+ +T + R N RS+R D K ++ EL++
Sbjct: 1667 INGRHYSTASTPPRRFNGADGDHSHDSVRSDRTADVLSFNNRQDLKTEVEELQN------ 1720
Query: 5419 RAQMAALEAKVQYLEDQLN--------VEGQEKTAANRAARRLEKRLNDTTQQFEDEKRA 5574
Q+ E K ++LE QL G+E +A R A++LE +A
Sbjct: 1721 --QLQLSEMKNRHLESQLERATPGPDATYGEESPSARRRAQKLE--------------QA 1764
Query: 5575 NEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELM 5748
N + +++L+ S+ K L + + E + +T+ E DLL++ E+ R L+
Sbjct: 1765 NSRLQDMLDDSSKKVSALEKTVRTGELSLRDIQTRS---HEEILDLLNSQEESRRSLL 1819
Score = 65.9 bits (159), Expect = 1e-08
Identities = 83/418 (19%), Positives = 183/418 (42%), Gaps = 13/418 (3%)
Frame = +1
Query: 3028 LTTQLLDHEERAKHGVKAKGRLENQLHELE-QDLNRERQYKSELEQHKRKLLAELEDSKD 3204
L +L D + +AK RL+++L + Q N +S +EQ ++K AE
Sbjct: 1965 LEEKLEDLSTDLEAATQAKRRLQHELEDYRAQRANDIEDKESSMEQTRKKYQAEFATLTK 2024
Query: 3205 HLAEKMGKVEELNNQ--LMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDM 3378
L + + E L Q +++ EEL +++D+E N + K+ ++ T+ ++
Sbjct: 2025 EL--DLAREERLFKQAEVVRLREELDELRSKWDDEVLNSSTWSKEKTRLEATLADVVASR 2082
Query: 3379 ETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRK----DEEVNATKRAI 3546
+ A N+A+ +++Q+ ++ + VDEA+ +D + R+ + + K +
Sbjct: 2083 DEAVGAHNEAQGKIVNLLSQVRTLRAN----VDEASAERDALLREKRGLESRLQEAKAGL 2138
Query: 3547 EQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALL 3726
E++ E A +++ EL + H+ S ++ +A+ A++ +++A
Sbjct: 2139 EELSKAGESPSLRNAAGMDKEILELKSSLAHHEDVASAAVEKMRRAEALVAEVQKDMAAE 2198
Query: 3727 QASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLN-RVREEEEHA 3903
+ + A + K++ E L E + L L ++ S ++ LN R+ E +E
Sbjct: 2199 RDNAAKLQKEKTALEKALSEEKVKLV-------NLETKVYPSAGQVKFLNTRIEEAQEEQ 2251
Query: 3904 FANMQRRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDE-----KEEAEG 4068
QR + + ++ + +D++N L + +++A+
Sbjct: 2252 HNKSQRSVRNVDRT---------------VKDLQSQIERKDKQNGQLQDDLTRMRDKADK 2296
Query: 4069 LRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKER 4242
L ++ E+ AA A R+AE ++L E ++K ++ L+++LE + + R
Sbjct: 2297 LLKTID-ELQAADSTAQLNARRAE----RELREEKEKTMQ----LERELESWKASAPR 2345
Score = 58.5 bits (140), Expect = 2e-06
Identities = 83/463 (17%), Positives = 189/463 (39%), Gaps = 8/463 (1%)
Frame = +1
Query: 4387 KALLDRDAMSQELRDRETRVLSL---LNEVDIMKEHLEESDRVRRSLQQELQDSISNKDD 4557
K LL + E++ R+ + L + + ++ ++ LEE R + +Q ++ ++
Sbjct: 918 KPLLGATRTATEVKRRDELIRQLHDKMKQEEMDRQRLEEERRTTHTEMMRIQQTLESERA 977
Query: 4558 FGKNVHELEKAKRSLEAELNDMRV----QMEELEDNLQIAEDARLRLEVTNQALKSESDR 4725
+ E+ K + E EL + E LED L DA+ E + +++ ++
Sbjct: 978 LALDKEEIFKRLQLREVELEEKLSGAIEDQERLEDQLDSLLDAKKLAEEQVEKYRTQLEQ 1037
Query: 4726 AISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANR 4905
A S + EE++ L ++ LE E++ + +S + + ++++I L+ QL + +R
Sbjct: 1038 AASLIG-KLEEEKTDLGDRLSSLEKEMKEMSQRQSQRSAEEEALQDEIKMLQSQLSLKDR 1096
Query: 4906 LKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEG 5085
+AR + + + ++A+ K A + E + + +
Sbjct: 1097 ------------------------KARDLEGKLLKIDQDAEVKLVAAQKELQTFKSREQR 1132
Query: 5086 LMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRK 5265
L+ + +K + R+ E+++A ++ ++++
Sbjct: 1133 LIAENRDAQQQLSKL----SKTSTDYEDLVRKKESELALLRSDNKKYETEHRSFEEQKKT 1188
Query: 5266 AQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEA 5445
+ E+ T L + ++++ L+R D K K+ + ++A LE
Sbjct: 1189 LAAEKEKAATRLREVQAEISALKSQQSQLQREADDAK-KLLQARLSEDAQADQNRQVLEG 1247
Query: 5446 KVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTT-QQFEDEKRANEQAKELLEKSNLKNR 5622
+++ L+D+L + Q + R +R L + Q+ ++E ++K +EK +
Sbjct: 1248 QIKDLKDEL-YKTQMDLSRERQSRDDVLLLGEHEYQKLQEEYERLNESKITIEKELYAQQ 1306
Query: 5623 NLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
+ R+ EA +ER + R+ R+ E+ RE N
Sbjct: 1307 DTLRRTMEARATAEKERDEARDEIRKLRVAKVQAEEARREAEN 1349
>gi|47205442|emb|CAG05719.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 1398
Score = 851 bits (2199), Expect = 0.0
Identities = 489/1356 (36%), Positives = 766/1356 (56%), Gaps = 114/1356 (8%)
Frame = +1
Query: 2020 FVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPD 2199
FVRCIIPNHEK++GK++++LVLEQLRCNGVLEGIRICRQGFPNR+ FQEFR RYEILTP
Sbjct: 1 FVRCIIPNHEKRAGKLDAHLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPS 60
Query: 2200 VIPKNFIDGKESVRKMITA-----------------------------------LDIDTN 2274
IPK F+DGK++ M+ LD+D N
Sbjct: 61 AIPKGFMDGKQACCLMVNTHSRKIPRLIIQHICTVKTHLLLCLMLSFPVLQIKHLDLDPN 120
Query: 2275 LYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXX 2454
L+RIGQSK+FFRTGVLA LEEERDLK+T +I+ FQAQ RGFL+R+ +
Sbjct: 121 LFRIGQSKIFFRTGVLAQLEEERDLKITVIIIAFQAQARGFLARKAFAKRQQQLTAMKVI 180
Query: 2455 XXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENE 2634
N AYLKLRNWQWWRLFTKVKPLLQVTR ++E+ KD+EL+ KE LK E + +E
Sbjct: 181 QRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMSLKDEELKRAKEVSLKFESELKEIA 240
Query: 2635 KKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXX 2814
K V+ ER +QEQLQ E+E AE +++R RL + QELE I+++M RL
Sbjct: 241 LKHTSVVEERNALQEQLQAETELFAEAEEMRVRLAAKKQELEEILHEMEARLDDEEERAQ 300
Query: 2815 XXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXX 2994
++K + +++ +K + +D +
Sbjct: 301 ALLLDKKKMQQQMQELEEHLEEEEDARQKLQLEKVTCEGKIKKLEDEILVMEDHNNKLLK 360
Query: 2995 XXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRK 3174
++T L + EE++K+ K K + E+ + ELE L +E + + EL++ KRK
Sbjct: 361 ERKLMEDRIADISTNLAEEEEKSKNLTKLKNKHESMISELEVRLKKEEKCRQELDKAKRK 420
Query: 3175 LLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTT 3354
L AE D ++ +A+ ++ EL QL K++EELQ+ L R ++E A K++R+++
Sbjct: 421 LEAESNDLQEQIADLQAQIAELKAQLAKKEEELQNALARLEDEMAQKNNALKKIRELEGH 480
Query: 3355 IDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNAT 3534
I +L+ED+++ER ARNKAE +R++ +LE +K ++ D +D Q+L +++++EV
Sbjct: 481 ISDLQEDLDSERAARNKAEKIKRDLGEELEALKSELEDTLDTTATQQELRAKREQEVTVL 540
Query: 3535 KRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQE 3714
KRAIE+ T E ++ E + K ++ VEEL +Q+EQ K+ +S LEK + ++E +++ E
Sbjct: 541 KRAIEEENRTHEAQVHEMRQKHTQAVEELTEQLEQSKRVKSNLEKAKQALEKETSELTME 600
Query: 3715 IALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEE 3894
+ L ++ D + KRK E + ++Q+ A+S++ K L ++ + EL+ + + E
Sbjct: 601 VRSLVQAKQDGEHKRKKLEGQVADLQSRFADSEKQKADLGERCSKITIELEGVTNLLNEA 660
Query: 3895 EHAFANMQRRLATAXX------XXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKE 4056
E + + +++ TR K+ + RQ ED+KN+L ++ E
Sbjct: 661 ESKNIKLSKDVSSITSQLQDTQIHLSQQELLAEETRQKLQLSTKLRQAEDDKNSLQEQLE 720
Query: 4057 EAEGLRAHLEKEIHAARQGAGEARRKAEESV--NQQLEELRKKNLRDVEHLQKQLEESEV 4230
E + ++E+ + ++++K EE + LEE +K+ RD+E Q EE
Sbjct: 721 EEMEAKRNVERHVSTLNLQLSDSKKKLEEMTANAEMLEESKKRLQRDLEAANTQYEEKAS 780
Query: 4231 AKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDA 4410
A +++ ++K ++QQELED+ M+L+N R + EK+QKKF+ +AEE+ K +RD
Sbjct: 781 AYDKLEKTKNRLQQELEDTLMDLDNQRQIVSNLEKKQKKFDQMLAEEKSISCKYAEERDR 840
Query: 4411 MSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKN------- 4569
E R++ET+ LSL ++ ++ EE +R ++L+ E++D IS+KDD GKN
Sbjct: 841 AEAEAREKETKALSLARALEEAQDSREELERANKALRIEMEDLISSKDDVGKNVGGNIQD 900
Query: 4570 ---------------------VHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRL 4686
VHELEK+KR LEA++ +M+ Q+EELED LQ AEDA+LRL
Sbjct: 901 CFLKGVFHRYMMVNSYVYFRQVHELEKSKRGLEAQVEEMKTQLEELEDELQAAEDAKLRL 960
Query: 4687 EVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQ 4866
EV QALK++ +R + +D EEK+R L+KQ+R+LE ELE+E++ ++ A + +KK+E
Sbjct: 961 EVNMQALKAQFERDLQGRDEMGEEKKRQLIKQVRELETELEDERKQRAQATAAKKKLETD 1020
Query: 4867 IGELEQQLEVANRLKEE-------------YXXXXXXXXXXXXEYQIECEEARQAKEDIA 5007
I +LE Q+E A++ ++E ++Q E ++A A+E++
Sbjct: 1021 IKDLEGQIETASKGRDEAIKQLRKFRHTPAAVSLSFSLQAQMKDFQRELDDAHAAREEVL 1080
Query: 5008 ALLREADRKFRAVEAEREQLREA-----------------NEGLM----------QARKQ 5106
+ +E+++K +++EAE QL+E GL +ARKQ
Sbjct: 1081 SAAKESEKKAKSLEAELMQLQEVTWLIPNTASAGGTRQTLRSGLFFFLQDLAAAERARKQ 1140
Query: 5107 XXX---XXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQ 5277
A G ++EKRRLEA+IAQ Q N EL D+ RK+ Q
Sbjct: 1141 AEAERDELADELASNASGKSALADEKRRLEARIAQLEEELEEEQGNMELLNDRLRKSSQQ 1200
Query: 5278 LEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQY 5457
++Q+ +L ER+ +QK E+ +Q LER N++ KAK+ E+E+ +S+ ++ ++ALEAKV
Sbjct: 1201 VDQLNNELQTERSTSQKNESARQQLERQNKELKAKLQEMENQVKSKFKSSISALEAKVAQ 1260
Query: 5458 LEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQ 5637
LE+QL E +EK A+ ++ R+ +K++ D Q EDE++ EQ K+ EKS + + L+RQ
Sbjct: 1261 LEEQLEQENREKQASAKSLRQKDKKMKDLIIQVEDERKQAEQYKDQAEKSTARVKQLKRQ 1320
Query: 5638 LDEAEDEMSRERTKHRNVQREADDLLDANEQLTREL 5745
L+E+E+E R R +QRE D+ + + L RE+
Sbjct: 1321 LEESEEESQRATAARRKLQRELDEATETADALGREV 1356
Score = 50.4 bits (119), Expect = 5e-04
Identities = 37/203 (18%), Positives = 91/203 (44%), Gaps = 11/203 (5%)
Frame = +1
Query: 3055 ERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKM-GKV 3231
+R + + +L N+L + + +LE+ ++L A+L++ ++ + K +
Sbjct: 1192 DRLRKSSQQVDQLNNELQTERSTSQKNESARQQLERQNKELKAKLQEMENQVKSKFKSSI 1251
Query: 3232 EELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
L ++ + +E+L+ + + ++ K+M+D+ +++ R+ E ++ K+
Sbjct: 1252 SALEAKVAQLEEQLEQENREKQASAKSLRQKDKKMKDLIIQVEDERKQAEQYKDQAEKST 1311
Query: 3412 MTRREVVAQLEK----------VKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQH 3561
+++ QLE+ + + ++DEAT D + R EVN+ K + +
Sbjct: 1312 ARVKQLKRQLEESEEESQRATAARRKLQRELDEATETADALGR---EVNSLKSKLRRGNE 1368
Query: 3562 TMEGKIEEQKAKFSRQVEELHDQ 3630
G + R VE++ D+
Sbjct: 1369 PSFGSTPRRMGGGRRVVEDMSDE 1391
>gi|3668187|dbj|BAA33452.1| myosin heavy chain [Theragra chalcogramma]
Length = 1287
Score = 848 bits (2192), Expect = 0.0
Identities = 473/1258 (37%), Positives = 742/1258 (58%), Gaps = 8/1258 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V D E ++ ++ + +V V ++ T + T+ DDV NPPK+DKIEDM+ +T+L
Sbjct: 39 YVADVKELYVKCTMTKRDAGKVTVTVLATKEERTVKEDDVYPMNPPKYDKIEDMAMMTHL 98
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
NEASVL+NL +RY + +IYTYSGLFC +NPYK LP+Y + + ++GKKR E PPHIF+
Sbjct: 99 NEASVLYNLAERYAAWMIYTYSGLFCATVNPYKWLPVYDQSCVNAYRGKKRMEAPPHIFS 158
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIV 627
++D A++ ML +RE+QS+L TGESGAGKT NTK+VIQY A +A + + A +
Sbjct: 159 VSDNAFQFMLTDRENQSVLITGESGAGKTVNTKRVIQYFATIAVGGGGEKADVGAGK--- 215
Query: 628 QKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIE 807
G LE Q++ ANP+LEA+GN+KTV+NDNSSRFGKFIRI+F +G +S A+IE
Sbjct: 216 -------IKGSLEDQIIAANPLLEAYGNAKTVRNDNSSRFGKFIRIHFHANGKLSSADIE 268
Query: 808 FYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRF-LVNRG-ITLPNV 981
YLLEKSRV Q DER +HIF+Q++ E E L + Y F + ++G IT+ ++
Sbjct: 269 TYLLEKSRVSFQLPDERGYHIFFQMMTN-HKPEIIEMTLITTNPYDFPMCSQGQITVASI 327
Query: 982 DDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQK 1161
DD +E +T ++ I+GF ++ +I + AVL GN++F Q+++ +QA + K
Sbjct: 328 DDKEELDATDAAIDILGFTSEDKVAIFKFTGAVLHHGNMKFKQKQREEQAEPDGNEEADK 387
Query: 1162 VCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLVTRI 1341
+C+LL L ++ KA PR+KVG E+V K Q Q +V A+AK+ YERLF W+V RI
Sbjct: 388 ICYLLSLNSADMLKALCYPRVKVGNEYVTKGQTVPQVNNSVSALAKSIYERLFLWMVIRI 447
Query: 1342 NKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQ 1521
N LD T + +IG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+TMF+LEQEEY+
Sbjct: 448 NTMLD-TKQARQFYIGVLDIAGFEIFDYNSMEQLCINFTNEKLQQFFNHTMFVLEQEEYK 506
Query: 1522 REGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NKHPK 1698
+EGI W+FIDFG+DL I+LIEKPMG+ ++L+EEC+FPKA+D +F KL H K+
Sbjct: 507 KEGIIWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKASDVTFKNKLFDQHLGKNRA 566
Query: 1699 FIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWK 1869
F P ++++HF++VHYAG VDY+ WL KN DPLN++V+GL Q S++ + ++
Sbjct: 567 FEKPKPAKDKAEAHFSLVHYAGTVDYNVTGWLDKNKDPLNDSVIGLYQKSSNKLLPVLYP 626
Query: 1870 DAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHE 2049
E+ G + + G +TVS +E L KLMT LR+T PHFVRC+IPN
Sbjct: 627 PV------VEEVGGAKKGGKKKGGSMQTVSSQFRENLGKLMTNLRSTHPHFVRCLIPNES 680
Query: 2050 KKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NFIDG 2226
K G + ++LV+ QLRCNGVLEGIRIC +GFP+R+ + +F+ RY++L VIP FID
Sbjct: 681 KTPGLMENHLVIHQLRCNGVLEGIRICTKGFPSRIIYADFKQRYKVLNASVIPDGQFIDN 740
Query: 2227 KESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSR 2406
K++ K++ ++D+ + Y+ G +KVFF+ G+L LEE RD KL AL+ QA RG++ R
Sbjct: 741 KKASEKLLGSIDVPHDEYKFGHTKVFFKAGLLGTLEEMRDEKLAALVGMIQAAGRGYVMR 800
Query: 2407 RLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRA 2586
+ Y N +++ +++W W +++ K+KPLL+ T+ E+ +
Sbjct: 801 KEYVKMTERREAVYTIQYNIRSFMNVKHWPWMKVYYKIKPLLKSAETEKELANMKENYDK 860
Query: 2587 TKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYI 2766
K L +E E+K+ ++ E+ + Q+ + +N + ++ L +LE
Sbjct: 861 MKTDLAAALAKKKELEQKMVSLLQEKNDLSLQMASDGDNLNDAEERCEGLIKAKIQLEAK 920
Query: 2767 VNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXX 2946
V + +RL +RK + + +K +
Sbjct: 921 VKETTERLEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 980
Query: 2947 XXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDL 3126
++ L E++ KAK +LE Q+ +LE L
Sbjct: 981 TEEMASQDESVAKLTKEKKALQESHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSL 1040
Query: 3127 NRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEES 3306
+E++ + +LE+ KRKL +L+ +++ + + ++ + ++ K+D E L++ ++E
Sbjct: 1041 EQEKKLRMDLERSKRKLEGDLKLAQETVMDLENDKQQSDEKIKKKDFETSQHLSKIEDEQ 1100
Query: 3307 ANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEAT 3486
+ +QK+++++Q I+EL E++E ER AR K E R ++ +LE++ + L++ AT
Sbjct: 1101 SLGAQLQKKIKELQARIEELEEEIEAERAARAKVEKQRADLSRELEEI-SERLEEAGGAT 1159
Query: 3487 MLQDLMSRKDE-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQL 3663
Q M++K E E +R +E+ E + K + V EL +QI+ ++ + +L
Sbjct: 1160 SAQIEMNKKREAEFQKLRRDLEESTLQHEATASALRKKQADSVAELGEQIDNLQRVKQKL 1219
Query: 3664 EKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLID 3837
EK++++ E D++ + + ++ +++K + E L EI+ A+SDE+ R + D
Sbjct: 1220 EKEKSEYKMEIDDLSSNMEAVSKAKGNLEKICRALEDQLSEIK---AKSDENARQVND 1274
Score = 88.2 bits (217), Expect = 2e-15
Identities = 106/453 (23%), Positives = 193/453 (42%), Gaps = 22/453 (4%)
Frame = +1
Query: 3076 KAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLA---EKMGKVEELNN 3246
K ++ +++ DL K ELEQ LL E D +A + + EE
Sbjct: 849 KELANMKENYDKMKTDLAAALAKKKELEQKMVSLLQEKNDLSLQMASDGDNLNDAEERCE 908
Query: 3247 QLMKRDEELQHQLTRY-----DEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
L+K +L+ ++ DEE N L K+ R ++ EL++D++ E
Sbjct: 909 GLIKAKIQLEAKVKETTERLEDEEEINAELTAKK-RKLEDECSELKKDIDD-------LE 960
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGK----- 3576
+T +V + + V + +E + +++ +E A + + +Q ++ +
Sbjct: 961 LTLAKVEKEKHATENKVKNLTEEMASQDESVAKLTKEKKALQESHQQTLDDLQAEEDKVN 1020
Query: 3577 -IEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIAL-----LQASR 3738
+ + K K +QV++L +EQ KK R LE+ + + + + +AQE + Q S
Sbjct: 1021 TLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERSKRKLEGD-LKLAQETVMDLENDKQQSD 1079
Query: 3739 ADIDKKRKIHEAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
I KK HL +I E +++L QL++ EL R+ E EE A
Sbjct: 1080 EKIKKKDFETSQHLSKI--------EDEQSLGAQLQKKIKELQ--ARIEELEEEIEAERA 1129
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
R +++ + +R+LE E + L+E A + + K+
Sbjct: 1130 AR------------------AKVEKQRADLSRELE-EISERLEEAGGATSAQIEMNKKRE 1170
Query: 4099 AARQGAGEARRKAEESVNQQ---LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQ 4269
A Q + RR EES Q LRKK V L +Q++ + K+++ + K + +
Sbjct: 1171 AEFQ---KLRRDLEESTLQHEATASALRKKQADSVAELGEQIDNLQRVKQKLEKEKSEYK 1227
Query: 4270 QELEDSSMELENVRASHRDSEKRQKKFESQMAE 4368
E++D S +E V + + EK + E Q++E
Sbjct: 1228 MEIDDLSSNMEAVSKAKGNLEKICRALEDQLSE 1260
Score = 75.1 bits (183), Expect = 2e-11
Identities = 80/444 (18%), Positives = 192/444 (43%), Gaps = 10/444 (2%)
Frame = +1
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDK-- 3753
E++ A +++ + ++ +LE++ QE+ D++ ++A + D ++
Sbjct: 848 EKELANMKENYDKMKTDLAAALAKKKELEQKMVSLLQEKNDLSLQMASDGDNLNDAEERC 907
Query: 3754 ----KRKIH-EAHLMEIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQ 3918
K KI EA + E L + +E L + + DE L + ++ E A ++
Sbjct: 908 EGLIKAKIQLEAKVKETTERLEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 967
Query: 3919 RRLATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIH 4098
+ T K+ N+ +DE A L ++++A +
Sbjct: 968 KE---------------KHATENKVKNLTEEMASQDESVAKLTKEKKA----------LQ 1002
Query: 4099 AARQGAGEARRKAEESVNQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQEL 4278
+ Q + + E+ VN L + + K + V+ L+ LE+ + + + +SK+K++ +L
Sbjct: 1003 ESHQQTLDDLQAEEDKVNT-LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERSKRKLEGDL 1061
Query: 4279 ---EDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVL 4449
+++ M+LEN + D + ++K FE+ ++ +++L + +++++ + R+
Sbjct: 1062 KLAQETVMDLENDK-QQSDEKIKKKDFETSQHLSKIEDEQSL--GAQLQKKIKELQARIE 1118
Query: 4450 SLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRV 4629
L E++ + + ++ R L +EL++ ++ G + + EAE +R
Sbjct: 1119 ELEEEIEAERAARAKVEKQRADLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKLRR 1178
Query: 4630 QMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELE 4809
+EE + A + + + A E + + E+++ +I DL + +E
Sbjct: 1179 DLEESTLQHEATASALRKKQADSVAELGEQIDNLQRVKQKLEKEKSEYKMEIDDLSSNME 1238
Query: 4810 NEKRGKSGAVSHRKKIENQIGELE 4881
+ K + +E+Q+ E++
Sbjct: 1239 AVSKAKGNLEKICRALEDQLSEIK 1262
Score = 69.7 bits (169), Expect = 8e-10
Identities = 106/532 (19%), Positives = 212/532 (38%), Gaps = 24/532 (4%)
Frame = +1
Query: 4030 KNALLDEKEEAEGLR-AHLEKEIHAARQGAGEARRKAEESVNQQLEELR--KKNLRDVEH 4200
K LL EE + A L I AA G G RK + ++ E + + N+R +
Sbjct: 768 KAGLLGTLEEMRDEKLAALVGMIQAA--GRGYVMRKEYVKMTERREAVYTIQYNIRSFMN 825
Query: 4201 LQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVA 4380
++ K + L + ++EL + + ++ + ++K+ E +M
Sbjct: 826 VKHWPWMKVYYKIKPLLKSAETEKELANMKENYDKMKTDLAAALAKKKELEQKMVSLLQE 885
Query: 4381 VQKALLDRDAMSQELRDRETRVLSLLN-------EVDIMKEHLEESDRVRRSL---QQEL 4530
L + L D E R L+ +V E LE+ + + L +++L
Sbjct: 886 KNDLSLQMASDGDNLNDAEERCEGLIKAKIQLEAKVKETTERLEDEEEINAELTAKKRKL 945
Query: 4531 QDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALK 4710
+D S + K++ +LE +E E + +++ L + + +++ +L +AL+
Sbjct: 946 EDECS---ELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMASQDESVAKLTKEKKALQ 1002
Query: 4711 SESDRAISNKDVEAEEKRRGLL--------KQIRDLENELENEKRGKSGAVSHRKKIENQ 4866
+ + D++AEE + L +Q+ DLE LE EK+ + ++K+E
Sbjct: 1003 ESHQQTLD--DLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERSKRKLEGD 1060
Query: 4867 IGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAV 5046
+ ++ + K++ ++ + E+ + + ++E + +
Sbjct: 1061 LKLAQETVMDLENDKQQSDEKIKKKDFETSQHLSKIEDEQSLGAQLQKKIKELQARIEEL 1120
Query: 5047 EAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISS---EEKRRLEAKIAQXXXXX 5217
E E E R A + + R + GG +S E ++ EA+ +
Sbjct: 1121 EEEIEAERAARAKVEKQRADLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKLRRDL 1180
Query: 5218 XXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELE 5397
E RK Q +L + Q+ KQ LE+ +YK +I +L
Sbjct: 1181 EESTLQHEATASALRKKQA---DSVAELGEQIDNLQRV---KQKLEKEKSEYKMEIDDLS 1234
Query: 5398 SGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQ 5553
S ++ ++A+ LE + LEDQL+ + K ++ AR ++ND + Q
Sbjct: 1235 SNMEAVSKAK-GNLEKICRALEDQLS---EIKAKSDENAR----QVNDISAQ 1278
Score = 54.3 bits (129), Expect = 4e-05
Identities = 42/177 (23%), Positives = 84/177 (46%)
Frame = +1
Query: 5167 EEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQ 5346
+EK L ++A + CE I + + + ++++ T L E +N + A+K+
Sbjct: 884 QEKNDLSLQMASDGDNLNDAEERCEGLIKAKIQLEAKVKETTERLEDEEEINAELTAKKR 943
Query: 5347 SLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLE 5526
LE + K I +LE ++ + A E KV+ L +++ Q+++ A +
Sbjct: 944 KLEDECSELKKDIDDLEL-TLAKVEKEKHATENKVKNLTEEM--ASQDESVAKLTKEK-- 998
Query: 5527 KRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQR 5697
K L ++ QQ D+ +A E L K+ K L +Q+D+ E + +E+ +++R
Sbjct: 999 KALQESHQQTLDDLQAEEDKVNTLTKAKTK---LEQQVDDLEGSLEQEKKLRMDLER 1052
Score = 36.2 bits (82), Expect = 9.9
Identities = 29/143 (20%), Positives = 64/143 (44%), Gaps = 9/143 (6%)
Frame = +1
Query: 5341 KQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAAN--RAA 5514
K++ ++ D A + + + Q + +Q D N+ E+ +A
Sbjct: 855 KENYDKMKTDLAAALAKKKELEQKMVSLLQEKNDLSLQMASDGDNLNDAEERCEGLIKAK 914
Query: 5515 RRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSR-ERTKH--- 5682
+LE ++ +TT++ EDE+ N + K + L++ +D+ E +++ E+ KH
Sbjct: 915 IQLEAKVKETTERLEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 974
Query: 5683 ---RNVQREADDLLDANEQLTRE 5742
+N+ E ++ +LT+E
Sbjct: 975 NKVKNLTEEMASQDESVAKLTKE 997
>gi|47220279|emb|CAG03313.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 691
Score = 848 bits (2190), Expect = 0.0
Identities = 426/698 (61%), Positives = 532/698 (76%), Gaps = 15/698 (2%)
Frame = +1
Query: 7 DLQYLQVQRAAVADPATLAAWAQRKLCWVPDQNEGFLIGSIKRETNDEVLVELVDTSRQV 186
D ++L V + + P A W+ +KL WVP + GF SIK E DEVLVEL D ++V
Sbjct: 9 DEKFLFVDKDLLNSPMAQADWSAKKLVWVPSEKHGFEAASIKEEHGDEVLVELADNGKKV 68
Query: 187 TISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYK 366
T+++DD+QK NPPKF K+EDM+ELT LNEASVLHNL++RYYS LIYTYSGLFCVV+NPYK
Sbjct: 69 TLNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVVNPYK 128
Query: 367 KLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTK 546
LPIYSE +IE +KGKKRHE+PPHI++IAD AYR+M+Q+REDQSILCTGESGAGKTENTK
Sbjct: 129 MLPIYSEKIIEMYKGKKRHEVPPHIYSIADNAYRNMMQDREDQSILCTGESGAGKTENTK 188
Query: 547 KVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVK 726
KVIQYLA VA + + K + IGELE QLLQANPILEAFGN+KT+K
Sbjct: 189 KVIQYLAMVASSHKGKK---------------DSSIGELEKQLLQANPILEAFGNAKTIK 233
Query: 727 NDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKE 906
NDNSSRFGKFIRINFD++GYI GANIE YLLEKSR +RQA+ ER+FHIFY ++ G K
Sbjct: 234 NDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRCIRQAKTERAFHIFYYMIAGARDKL 293
Query: 907 KSEYLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLL 1086
+ E LLE NYRFL + + + D + + T+ +M IMGF+++E + I++V S V+
Sbjct: 294 REELLLEPFSNYRFLSDGHVQITGQQDDELYDETMEAMNIMGFSEEERNDILKVCSTVMQ 353
Query: 1087 LGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQE 1266
LGN+EF +E+ +QA + D+ QKVCHL G+ V + +A L PRIKVGRE V KAQ +E
Sbjct: 354 LGNIEFKKERNQEQATMPDNTAAQKVCHLQGINVTDFTRAILTPRIKVGREMVQKAQTKE 413
Query: 1267 Q-------AEFAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDI 1425
Q A+FA+EA+AKA +ERLF+W+++R+NK+LD+T RQGASF+GILDIAGFEIF+
Sbjct: 414 QARPTEHHADFAIEALAKAIFERLFRWILSRVNKALDKTKRQGASFLGILDIAGFEIFED 473
Query: 1426 NSFEQICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEK---P 1596
NSFEQ+CINYTNEKLQQLFN+TMFILEQEEYQREGIEW+FIDFGLDLQP I+LIE+ P
Sbjct: 474 NSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNP 533
Query: 1597 MGVLALLDEECLFPKANDKSFVEKLQKTHNKHPKFI-VPDMRSKSHFAVVHYAGRVDYSA 1773
G+LALLDEEC FPKA D SFVEKL T H KF ++ K+ F+++HYAG+VDY+A
Sbjct: 534 PGILALLDEECWFPKATDVSFVEKLINTQGNHIKFAKSKQLKDKTEFSLLHYAGKVDYNA 593
Query: 1774 DQWLMKNMDPLNENVVGLMQNSTDPFVAGIWKDAE-FAGI-CAAEMNETAF--GMRSRKG 1941
WL KNMDPLN+NV L+ NS+ FV +WKD + G+ A+M++T+ +++KG
Sbjct: 594 TAWLTKNMDPLNDNVTTLLSNSSSQFVQDLWKDTDRVVGLDTLAKMSDTSMPSASKTKKG 653
Query: 1942 MFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKK 2055
MFRTV QL+KE L KLMTTL NT P+FVRCIIPNHEK+
Sbjct: 654 MFRTVGQLYKESLAKLMTTLHNTQPNFVRCIIPNHEKR 691
>gi|27469623|gb|AAH41716.1| MYH4 protein [Xenopus laevis]
Length = 1170
Score = 846 bits (2186), Expect = 0.0
Identities = 466/1155 (40%), Positives = 704/1155 (60%), Gaps = 10/1155 (0%)
Frame = +1
Query: 88 WVPDQNEGFLIGSIKRETNDEVLVELVDTSRQVTISRDDVQKANPPKFDKIEDMSELTYL 267
+V D E ++ G + + +V V+ D R VT+ + NPPK+DKIEDM+ +T+L
Sbjct: 38 FVDDAKELYVKGLVTAREDGKVTVK-TDDGRTVTVKESQIYPQNPPKYDKIEDMAMMTHL 96
Query: 268 NEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFA 447
NEASVL+NLK+RY + +IYTYSGLFC +NPYK LP+Y+ +++ ++GKKR E PPHIF+
Sbjct: 97 NEASVLYNLKERYAAWMIYTYSGLFCATVNPYKWLPVYNPEVVAGYRGKKRMETPPHIFS 156
Query: 448 IADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAG---ATRNKSLNAAAQQ 618
++D AY++ML +RE+QS+L TGESGAGKT NTK+VIQY A +A A + K L+ + Q
Sbjct: 157 LSDNAYQAMLTDRENQSVLITGESGAGKTVNTKRVIQYFATIAALGDAGKKKELSNSLQ- 215
Query: 619 NIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGA 798
G LE Q++QANP+LEAFGN+KTV+NDNSSRFGKFIRI+F +G +S A
Sbjct: 216 ------------GNLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLSSA 263
Query: 799 NIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRF-LVNRG-ITL 972
+IE YLLEKSRV Q ERS+HIFYQIL E E LL + Y F +++G I +
Sbjct: 264 DIETYLLEKSRVTFQLSAERSYHIFYQILTN-KKPELVEMLLVTTNPYDFPSISQGEIVV 322
Query: 973 PNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRV 1152
+++D E +T +++ I+GF +E I ++ AV+ GNL+F Q+++ +QA V
Sbjct: 323 KSINDEDELMATDSAIDILGFNQEEKLGIYKMTGAVMHYGNLKFKQKQREEQAEPDSVEV 382
Query: 1153 IQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKASYERLFKWLV 1332
K+ +L+GL +L KA PR+KVG EFV K Q Q +V A++K+ +E+LF W+V
Sbjct: 383 ADKIAYLMGLNSADLLKALCYPRVKVGNEFVTKGQTVPQVYNSVGALSKSVFEKLFLWMV 442
Query: 1333 TRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQE 1512
TRIN+ LD T + FIG+LDIAGFEIFD NS EQ+CIN+TNEKLQQ FN+ MF+LEQE
Sbjct: 443 TRINQQLD-TKQPRQFFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQE 501
Query: 1513 EYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLFPKANDKSFVEKLQKTH-NK 1689
EY++EGI+W+FIDFG+DL I+LIEKP+G+ ++L+E+C+FPK+ D SF +KL + H K
Sbjct: 502 EYKKEGIDWEFIDFGMDLAACIELIEKPLGIFSILEEQCMFPKSTDNSFKDKLYEQHLGK 561
Query: 1690 HPKFIVPDM---RSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAG 1860
F P ++++HF++VHYAG VDY+ WL KN DPLNE+V+ L Q S+ ++
Sbjct: 562 CKNFEKPKPGKGKAEAHFSLVHYAGTVDYNISGWLEKNKDPLNESVIQLFQKSSVKLLSM 621
Query: 1861 IWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIP 2040
+ ++ AA+ G + + F+TVS L +E L KLM+ LR+T PHFVRC+IP
Sbjct: 622 L-----YSTFAAADDAGGKGGKKKKGSAFQTVSGLFRENLGKLMSNLRSTHPHFVRCLIP 676
Query: 2041 NHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPK-NF 2217
N K G ++++L++ QLRCNGVLEGIRICR+GFP+R+ + +F+ RY++L IP+ F
Sbjct: 677 NESKTPGIMDNHLLIHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQF 736
Query: 2218 IDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGF 2397
ID K++ K++ ++DID Y++G +KVFF+ G+L LEE RD KL LI QA CRGF
Sbjct: 737 IDNKKACEKLLGSIDIDHTQYKLGHTKVFFKAGLLGTLEEMRDEKLAQLITCTQALCRGF 796
Query: 2398 LSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDE 2577
L R + N +++ +++W W +L+ K+KPLLQ T+ E+ +E
Sbjct: 797 LMRVEFKKMMERREAIYVIQYNLRSFMNVKHWPWMKLYFKIKPLLQSAETEKEMANMKEE 856
Query: 2578 LRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQEL 2757
TKE L+K E +E E+K+ ++ E+ + Q+Q E E A+ ++ L +L
Sbjct: 857 FEKTKEALVKAEAKKKELEEKMVSLLQEKNDLVLQVQSEGETLADSEERCEGLIKSKIQL 916
Query: 2758 EYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXX 2937
E + ++ +RL +RK + + +K +
Sbjct: 917 ESKLKELTERLEDEEESNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKV 976
Query: 2938 XXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELE 3117
+ L E++ KAK +LE Q+ +LE
Sbjct: 977 KNLTEEMAALDENISKLSKEKKALQEAHQQTLDDLQAEEDKVSSLSKAKTKLEQQVDDLE 1036
Query: 3118 QDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYD 3297
L +E++ + + E+ KRKL +L+ +++ + + ++ +L K+D E+ + +
Sbjct: 1037 GSLEQEKKLRLDFERAKRKLEGDLKLTQETVMDLENDKQQTEEKLKKKDFEISQLQGKIE 1096
Query: 3298 EESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVD 3477
+E + +QK+++++Q I+EL E++E ER AR K E R ++ +LE++ + L++
Sbjct: 1097 DEQSLGIQLQKKIKELQARIEELEEEIEAERAARAKVEKQRADLSRELEEI-SERLEEAG 1155
Query: 3478 EATMLQDLMSRKDEE 3522
AT Q M++K ++
Sbjct: 1156 GATSAQIEMNKKKKK 1170
Score = 90.5 bits (223), Expect = 4e-16
Identities = 73/275 (26%), Positives = 139/275 (50%), Gaps = 34/275 (12%)
Frame = +1
Query: 3040 LLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKL-------------- 3177
L D EER + +K+K +LE++L EL + L E + +EL KRKL
Sbjct: 899 LADSEERCEGLIKSKIQLESKLKELTERLEDEEESNAELTAKKRKLEDECSELKKDIDDL 958
Query: 3178 ---LAELEDSK-------DHLAEKMGKVEELNNQLMKRDEELQ--HQLTRYD--EESANV 3315
LA++E K +L E+M ++E ++L K + LQ HQ T D E V
Sbjct: 959 ELTLAKVEKEKHATENKVKNLTEEMAALDENISKLSKEKKALQEAHQQTLDDLQAEEDKV 1018
Query: 3316 TLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQ 3495
+ + K ++ +D+L +E E+ R E +R++ L+ + V+D ++ +
Sbjct: 1019 SSLSKAKTKLEQQVDDLEGSLEQEKKLRLDFERAKRKLEGDLKLTQETVMDLENDKQQTE 1078
Query: 3496 DLMSRKDEEVNATKRAIEQIQH---TMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLE 3666
+ + +KD E++ + IE Q ++ KI+E +A+ +EEL ++IE + R+++E
Sbjct: 1079 EKLKKKDFEISQLQGKIEDEQSLGIQLQKKIKELQAR----IEELEEEIEAERAARAKVE 1134
Query: 3667 KQQNQADQERADMA---QEIALLQASRADIDKKRK 3762
KQ+ +E +++ +E +++ +++KK+K
Sbjct: 1135 KQRADLSRELEEISERLEEAGGATSAQIEMNKKKK 1169
Score = 60.1 bits (144), Expect = 6e-07
Identities = 80/413 (19%), Positives = 176/413 (42%), Gaps = 32/413 (7%)
Frame = +1
Query: 3166 KRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDM 3345
K LL LE+ +D EK+ ++ Q + R ++ + + E + ++Q +R
Sbjct: 767 KAGLLGTLEEMRD---EKLAQLITCT-QALCRGFLMRVEFKKMMERREAIYVIQYNLRSF 822
Query: 3346 QTT-----------IDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATML 3492
I L + ETE+ N E + A VK + K E M+
Sbjct: 823 MNVKHWPWMKLYFKIKPLLQSAETEKEMANMKEEFEKTKEAL---VKAEAKKKELEEKMV 879
Query: 3493 QDLMSRKDE--EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLE 3666
L + D +V + + + EG I+ K + +++EL +++E ++ ++L
Sbjct: 880 SLLQEKNDLVLQVQSEGETLADSEERCEGLIKS-KIQLESKLKELTERLEDEEESNAELT 938
Query: 3667 KQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDE---------- 3816
++ + + E +++ ++I L+ + A ++K++ E + + +A DE
Sbjct: 939 AKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAALDENISKLSKEKK 998
Query: 3817 -----HKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXXXXXXXXXXXXXT 3981
H++TL D L+ D++ L++ + + E +++ L
Sbjct: 999 ALQEAHQQTL-DDLQAEEDKVSSLSKAKTKLEQQVDDLEGSLEQEK-------------- 1043
Query: 3982 RLKIANINRARQLEDE----KNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESV 4149
+L++ R+LE + + ++D + + + L+K+ Q G+ + E+S+
Sbjct: 1044 KLRLDFERAKRKLEGDLKLTQETVMDLENDKQQTEEKLKKKDFEISQLQGKI--EDEQSL 1101
Query: 4150 NQQLEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENV 4308
QL+ + ++ LQ ++EE E E ++ K++++ D S ELE +
Sbjct: 1102 GIQLQ-------KKIKELQARIEELEEEIEAERAARAKVEKQRADLSRELEEI 1147
Score = 60.1 bits (144), Expect = 6e-07
Identities = 64/304 (21%), Positives = 132/304 (43%), Gaps = 18/304 (5%)
Frame = +1
Query: 4243 ILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQE 4422
+LQS + ++E+ + E E + + +E ++K+ E +M +L + +
Sbjct: 840 LLQSAET-EKEMANMKEEFEKTKEALVKAEAKKKELEEKMVSLLQEKNDLVLQVQSEGET 898
Query: 4423 LRDRETRVLSLL-------NEVDIMKEHLEESDRV-------RRSLQQELQDSISNKDDF 4560
L D E R L+ +++ + E LE+ + +R L+ E + + DD
Sbjct: 899 LADSEERCEGLIKSKIQLESKLKELTERLEDEEESNAELTAKKRKLEDECSELKKDIDDL 958
Query: 4561 GKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQA----LKSESDRA 4728
+ ++EK K + E ++ ++ +M L++N+ + L+ +Q L++E D+
Sbjct: 959 ELTLAKVEKEKHATENKVKNLTEEMAALDENISKLSKEKKALQEAHQQTLDDLQAEEDKV 1018
Query: 4729 ISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRL 4908
S + + L +Q+ DLE LE EK+ + ++K+E G+L+ E L
Sbjct: 1019 SSLSKAKTK-----LEQQVDDLEGSLEQEKKLRLDFERAKRKLE---GDLKLTQETVMDL 1070
Query: 4909 KEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGL 5088
+ + + E + + ED +L + +K + ++A E+L E E
Sbjct: 1071 END----KQQTEEKLKKKDFEISQLQGKIEDEQSLGIQLQKKIKELQARIEELEEEIEAE 1126
Query: 5089 MQAR 5100
AR
Sbjct: 1127 RAAR 1130
Score = 52.8 bits (125), Expect = 1e-04
Identities = 45/192 (23%), Positives = 89/192 (45%)
Frame = +1
Query: 5167 EEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEKQ 5346
+EK L ++ + CE I + + + +L+++T L E N + A+K+
Sbjct: 883 QEKNDLVLQVQSEGETLADSEERCEGLIKSKIQLESKLKELTERLEDEEESNAELTAKKR 942
Query: 5347 SLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRLE 5526
LE + K I +LE ++ + A E KV+ L +++ + + ++ +
Sbjct: 943 KLEDECSELKKDIDDLEL-TLAKVEKEKHATENKVKNLTEEMAALDENISKLSKE----K 997
Query: 5527 KRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREAD 5706
K L + QQ D+ +A E L K+ K L +Q+D+ E + +E+ + +R A
Sbjct: 998 KALQEAHQQTLDDLQAEEDKVSSLSKAKTK---LEQQVDDLEGSLEQEKKLRLDFER-AK 1053
Query: 5707 DLLDANEQLTRE 5742
L+ + +LT+E
Sbjct: 1054 RKLEGDLKLTQE 1065
>gi|47227314|emb|CAF96863.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 1788
Score = 845 bits (2184), Expect = 0.0
Identities = 569/1795 (31%), Positives = 924/1795 (50%), Gaps = 110/1795 (6%)
Frame = +1
Query: 655 GELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIEFY------- 813
G LE Q+++ANP +EAFGN+KT++NDNSSRFGKFIRI+F +G ++ A+I+
Sbjct: 48 GTLEDQIIEANPAMEAFGNAKTIRNDNSSRFGKFIRIHFGHTGKLASADIDICENMKESD 107
Query: 814 ----------------LLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYR 945
LLEKSRV+ Q ERS+HI+YQI+ E + LL + Y
Sbjct: 108 FSSLCQHLTRSICSPDLLEKSRVIFQQPGERSYHIYYQIMSQ-KKPELLDMLLVSSNPYD 166
Query: 946 F-LVNRGIT-LPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKK 1119
+ ++G+T + ++DD QE +T ++M I+GF DE ++V A++ GN++F Q+++
Sbjct: 167 YHFCSQGVTTVESMDDGQELMATDHAMDILGFLPDEKYGCYKIVGAIMHFGNMKFKQKQR 226
Query: 1120 SDQAMLQDDRV--------IQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAE 1275
+QA K +L+G+ +L K L PR+KVG E+V K QN EQ
Sbjct: 227 EEQAEADGTESGSTSEHFGADKASYLMGVSSADLIKGLLHPRVKVGNEYVVKGQNVEQVN 286
Query: 1276 FAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINY 1455
+AV A+AKA+Y+R+FKWLV RIN++L T FIG+LDIAGFEIF++NSFEQ+CIN+
Sbjct: 287 YAVGALAKATYDRMFKWLVGRINRTL-YTSLPRQYFIGVLDIAGFEIFELNSFEQLCINF 345
Query: 1456 TNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLF 1635
TNEKLQQ FN+ MFILEQEEY+REGIEW FIDFGLDLQ IDLIEKPMG++++L+EEC+F
Sbjct: 346 TNEKLQQFFNHHMFILEQEEYKREGIEWTFIDFGLDLQACIDLIEKPMGIMSILEEECMF 405
Query: 1636 PKANDKSFVEKLQKTH-NKHPKFIV--PDMRSK--SHFAVVHYAGRVDYSADQWLMKNMD 1800
PKA D SF KL H K P F PD + K +HF ++HYAG V Y+ WL KN D
Sbjct: 406 PKATDNSFKAKLYDNHIGKSPNFQKPRPDKKRKYEAHFELIHYAGVVPYNIVGWLDKNKD 465
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRK-GMFRTVSQLHKEQ 1977
PLNE VV Q S + +A ++++ + G +A +++ + +K F+TVSQLHKE
Sbjct: 466 PLNETVVACFQKSANKLLASLYEN--YVGSDSASDHKSGTKEKRKKAASFQTVSQLHKEN 523
Query: 1978 LTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVP 2157
L KLMT LR+T PHFVRCIIPN K G ++ LVL QLRCNGVLEGIRICR+GFPNR+
Sbjct: 524 LNKLMTNLRSTQPHFVRCIIPNETKTPGIMDPFLVLHQLRCNGVLEGIRICRKGFPNRIL 583
Query: 2158 FQEFRHR--------------------------YEILTPDVIPKN-FIDGKESVRKMITA 2256
+ EF+ R Y IL P IP + F+D ++ K+++
Sbjct: 584 YAEFKQRYCSSSVQSLVQSEPRKNSDSLAVFCSYRILNPQAIPDDKFVDSRKGAEKLLST 643
Query: 2257 LDIDTNLYRIGQSKVFFRTGVLAHLEEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXX 2436
LDID N YR G +KVFF+ G+L HLEE RD +L ++ QA RG + R
Sbjct: 644 LDIDHNQYRFGHTKVFFKAGLLGHLEEMRDERLAKVLTLLQAAARGKIMRMELRKMMERR 703
Query: 2437 XXXXXXXXNGLAYLKLRNWQWWRLFTKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEH 2616
N A+ +++W W +LF K+KPLL+ T+ E+ + +EL KE L K E
Sbjct: 704 EALMIIQWNIRAFNAVKHWPWMKLFFKIKPLLRSATTEKELASLKEELAKLKEALEKSEV 763
Query: 2617 DFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSX 2796
+E E++ ++ E+ + QLQ E +N A+ ++ L +LE V ++ +RL
Sbjct: 764 KRKELEERQVSLMQEKNDLSLQLQAEQDNLADAEERCDLLIKTKIQLEAKVKEIMERLED 823
Query: 2797 XXXXXXXXXXXRRKQMETVRDXXXXXXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDA 2976
+RK V++ + +D+ Q+A
Sbjct: 824 EEEINASILASKRKLAGRVKN--------------LIEEMAALDETILKLTKEKKALQEA 869
Query: 2977 YDXXXXXXXXXXXXXXGLTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSEL 3156
+ L E++ KAK +LE Q+ + N+ ++ + +L
Sbjct: 870 HQQT--------------LDDLQAEEDKVNTLTKAKIKLEQQVDDAH--WNKRKKLRMDL 913
Query: 3157 EQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEELQHQLTRYDEESANVTLMQKQM 3336
E+ KRKL +L+ S + + + ++L +L K+D E+ TR ++E A V+ +QK++
Sbjct: 914 ERAKRKLEGDLKLSLESIMDLENDKQQLEEKLKKKDFEMNELSTRVEDEQALVSQLQKKI 973
Query: 3337 RDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKD 3516
+++Q +EL E++E+ER R K E R EV +LE++ + L++ AT Q M++K
Sbjct: 974 KELQARTEELEEELESERACRAKVEKQRSEVARELEEL-SERLEEAGGATSAQIEMNKKR 1032
Query: 3517 E-EVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQE 3693
E + +R +E+ E + K + V EL +QI+ ++ + +LEK++++A E
Sbjct: 1033 EADFLKLRRDLEEAMLHHEATTAALRKKHADSVAELSEQIDSLQRVKQKLEKERSEAKME 1092
Query: 3694 RADMAQEIALLQASRADIDKKRKIHEAHLMEIQANLAESDEHKRTLID---QLERSRDEL 3864
D+A + L ++A +K ++ E + E + A++DE +R L D Q R++ E
Sbjct: 1093 IDDLASTVEQLSKNKASSEKTSRLFEDQMNEAK---AKADELQRQLNDSNTQRARAQTES 1149
Query: 3865 DHLNRVREEEEHAFANMQRRLATAXXXXXXXXXX-----------XXXXTRLKIANINRA 4011
L+R EE E + +QR + + K + +
Sbjct: 1150 GELSRKLEEREAMVSQLQRSKNSFSQSVEELKKQLDEENKNLQGWTRFSPKAKSSLAHAL 1209
Query: 4012 RQLEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESV---NQQLEELRKKN 4182
+ + + L ++ EE + +A L++ + A + R K E ++LEE +KK
Sbjct: 1210 QSSRHDCDLLREQYEEEQEAKAELQRALSKANAEVAQWRTKYETDAIQRTEELEEAKKKL 1269
Query: 4183 LRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQM 4362
+ ++ ++ +E S + ++K ++Q E+ED ++LE A+ +K+Q+ F+ +
Sbjct: 1270 VTRLQEAEETVEASNAKSSSLEKTKHRLQTEIEDLVVDLERANAAAAALDKKQRNFDKVL 1329
Query: 4363 AEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSI 4542
AE R ++ + +A +E R T + L N + +HLE R ++LQ+E+ D
Sbjct: 1330 AECRQKYEECQSELEASQKESRSLSTELFKLKNSYEETLDHLETVKRENKNLQEEITDLT 1389
Query: 4543 SNKDDFGKNVHELEKAKRSLEAELNDMRVQMEELEDN--LQIAEDARLRLEVTNQALKSE 4716
K +HELEK K+ LE E N+++ +EE+E + +L + ++ S
Sbjct: 1390 DQISQGAKTIHELEKMKKGLEMEKNEIQAALEEVEVSTFTSCCTCCQLLPDRCHRGSVSL 1449
Query: 4717 SDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEV 4896
S + +++ ++ + L + D++ +L E+RG R+ + Q+ EL++
Sbjct: 1450 SQGTLEHEESKSLRIQLELNQIKADVDRKLGRERRGT------RQPSDIQL-ELDETAHK 1502
Query: 4897 ANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREA 5076
LKE+ E E++ ALL + DR + E E L EA
Sbjct: 1503 NEELKEQAVVTERRNNLLAAEV-----------EELRALLEQNDRARKLAEHE---LLEA 1548
Query: 5077 NEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDK 5256
E + Q +K++LE ++ C A DK
Sbjct: 1549 TERVNLLHSQNTSLI---------------NQKKKLENDLSTLSNEVDDAVQECRNAEDK 1593
Query: 5257 QRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAA 5436
+KA + + +L E+ + E K+++E++ +D + ++ E E A + Q+
Sbjct: 1594 AKKA-MHRSMMAEELKKEQDTSAHLERMKKNMEQTVKDLQMRLDEAEQIALKGGKKQVQK 1652
Query: 5437 LEAKVQY------------------------LEDQLNVEGQEKTAANRAARRLEKRLNDT 5544
LEA+V+ LE++L+ E ++ + R+ E+R+ +
Sbjct: 1653 LEARVRLGINEGSGQTVPSPDWIRCDRQVRELENELDSEQKKSQEFQKGVRKYERRIKEL 1712
Query: 5545 TQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADD 5709
+ Q E++K+ + ++L++K +K ++ +RQ +EAE++ + +K+R +Q E +D
Sbjct: 1713 SYQAEEDKKNLIRLQDLIDKLQVKVKSYKRQTEEAEEQANCNLSKYRKLQHELND 1767
Score = 60.1 bits (144), Expect = 6e-07
Identities = 108/576 (18%), Positives = 228/576 (38%), Gaps = 2/576 (0%)
Frame = +1
Query: 4018 LEDEKNALLDEKEEAEGLRAHLEKEIHAARQGAGEARRKAEESVNQQLEELRKKNLRDVE 4197
+ D+K +D ++ AE L + L+ + + R G + KA + LEE+R + L V
Sbjct: 625 IPDDK--FVDSRKGAEKLLSTLDIDHNQYRFGHTKVFFKA--GLLGHLEEMRDERLAKVL 680
Query: 4198 HLQKQLEESEVAKERILQSKKKIQQELEDSSMELE-NVRASHRDSEKRQKKFESQMAEER 4374
L + A+ +I++ + + E ++ M ++ N+RA + K ++
Sbjct: 681 TLLQA-----AARGKIMRMELRKMMERREALMIIQWNIRAFNAVKHWPWMKLFFKI---- 731
Query: 4375 VAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKD 4554
K LL +EL SL E+ +KE LE+S+ R+
Sbjct: 732 ----KPLLRSATTEKELA-------SLKEELAKLKEALEKSEVKRK-------------- 766
Query: 4555 DFGKNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDARLRLEVTNQALKSESDRAIS 4734
ELE+ + SL E ND+ +Q++ +DNL AE+ D I
Sbjct: 767 -------ELEERQVSLMQEKNDLSLQLQAEQDNLADAEE--------------RCDLLIK 805
Query: 4735 NKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKE 4914
K ++ E K ++++ LE+E+ + ++ ++K+ ++ L E
Sbjct: 806 TK-IQLEAK-------VKEIMERLEDEEEINASILASKRKLAGRV----------KNLIE 847
Query: 4915 EYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQ 5094
E E + E +Q +D+ A E D+ +A+ + ++ ++
Sbjct: 848 EMAALDETILKLTKEKKALQEAHQQTLDDLQA---EEDKVNTLTKAKIKLEQQVDDAHWN 904
Query: 5095 ARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQV 5274
RK+ KR+LE + +++ + +K +K
Sbjct: 905 KRKKLRMDL--------------ERAKRKLEGDLKLSLESIMDLENDKQQLEEKLKKKDF 950
Query: 5275 QLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQ 5454
++ +++T + E+ L + + + + L+ + + ++ E E +++ Q + + +++
Sbjct: 951 EMNELSTRVEDEQALVSQLQKKIKELQARTEELEEEL-ESERACRAKVEKQRSEVARELE 1009
Query: 5455 YLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQAKELLEKSNLKN-RNLR 5631
L ++L G +A ++ E + E+ +E L K + + L
Sbjct: 1010 ELSERLEEAGGATSAQIEMNKKREADFLKLRRDLEEAMLHHEATTAALRKKHADSVAELS 1069
Query: 5632 RQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTR 5739
Q+D + + + + E DDL EQL++
Sbjct: 1070 EQIDSLQRVKQKLEKERSEAKMEIDDLASTVEQLSK 1105
Score = 59.7 bits (143), Expect = 8e-07
Identities = 26/47 (55%), Positives = 38/47 (80%)
Frame = +1
Query: 184 VTISRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIY 324
+T+ D+Q+ NPPK+D IEDM+ +T+LNEASVL+NL+ RY + +IY
Sbjct: 1 LTVKDGDIQQMNPPKYDLIEDMAMVTHLNEASVLYNLRRRYSAWMIY 47
>gi|31235874|ref|XP_319314.1| ENSANGP00000022367 [Anopheles gambiae]
gi|30174791|gb|EAA43617.1| ENSANGP00000022367 [Anopheles gambiae str.
PEST]
Length = 1644
Score = 843 bits (2179), Expect = 0.0
Identities = 526/1632 (32%), Positives = 879/1632 (53%), Gaps = 27/1632 (1%)
Frame = +1
Query: 916 YLLEGVDNYRFLVNRGITLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGN 1095
+L + +Y + IT+PNVDD +E T + ++GF +E +I R+ SAV+ +G
Sbjct: 3 FLSNDIYDYNSVSQGKITIPNVDDGEECLLTDEAFNVLGFTQEEKDNIYRITSAVMHMGR 62
Query: 1096 LEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAE 1275
++F Q+ + +QA +V LLG+ +L K L+PRIKVG EFV K QN++Q
Sbjct: 63 MQFKQKGREEQAEADGTEDGDRVAKLLGVGTDDLYKNLLKPRIKVGNEFVTKGQNKDQVT 122
Query: 1276 FAVEAIAKASYERLFKWLVTRINKSLDRTHRQGASFIGILDIAGFEIFDINSFEQICINY 1455
+V A+ K ++RLFKWLV + N++LD T ++ A FIG+LDIAGFEIFD N FEQ+CIN+
Sbjct: 123 NSVGALCKGIFDRLFKWLVKKCNETLD-TKQKRAQFIGVLDIAGFEIFDFNGFEQLCINF 181
Query: 1456 TNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIEKPMGVLALLDEECLF 1635
TNEKLQQ FN+ MF+LEQEEY++EGI W FIDFG+DL IDLIEKPMG+L++L+EE +F
Sbjct: 182 TNEKLQQFFNHHMFVLEQEEYKKEGINWAFIDFGMDLLACIDLIEKPMGILSILEEESMF 241
Query: 1636 PKANDKSFVEKLQKTH-NKHPKFIVPDMRS----KSHFAVVHYAGRVDYSADQWLMKNMD 1800
PKA D++F EKL H K F+ P HFA+ HYAG V Y+ WL KN D
Sbjct: 242 PKATDQTFAEKLMTNHLGKSAPFMKPRPPKPGIPAGHFAIGHYAGVVSYNITGWLEKNKD 301
Query: 1801 PLNENVVGLMQNSTDPFVAGIWKD--AEFAGICAAEMNETAFGMRSRKGM-FRTVSQLHK 1971
PLN+ VV + ++ + I+ D + A AA+ G R +KG F TVS +K
Sbjct: 302 PLNDTVVDQFKKGSNALMVEIFADHPGQSADPAAAK------GGRGKKGAGFATVSSSYK 355
Query: 1972 EQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNR 2151
EQL LMTTL++T PHFVRCIIPN K +G ++++LV+ QL CNGVLEGIRICR+GFPNR
Sbjct: 356 EQLNNLMTTLKSTQPHFVRCIIPNEMKTAGVVDAHLVMHQLTCNGVLEGIRICRKGFPNR 415
Query: 2152 VPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFRTGVLAHL 2331
+ + +F+ RY IL P + D K+ + ++ A +D+ LYR+G +KVFFR GVL +
Sbjct: 416 MMYPDFKLRYMILNPKGVEAE-KDLKKCAQVIMDAAGLDSELYRLGNTKVFFRAGVLGQM 474
Query: 2332 EEERDLKLTALIMNFQAQCRGFLSRRLYTXXXXXXXXXXXXXXNGLAYLKLRNWQWWRLF 2511
EE RD +L+ ++ QA CRG+LSR+ + N YLKLR W WW+L+
Sbjct: 475 EEFRDERLSKIMSWMQAWCRGYLSRKEFKKMQEQRVSLEIVQRNLRKYLKLRTWAWWKLW 534
Query: 2512 TKVKPLLQVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQ 2691
KVKPLL V+R +D+I +++ +E K E +E E +++ E+ + + L
Sbjct: 535 QKVKPLLNVSRVEDQIAKLEEKATKAQEAYEKEEKLRKELEALNSKLLAEKTALLDSLSG 594
Query: 2692 ESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXX 2871
E E + +L + +LE + D ++RL+ ++K + +
Sbjct: 595 EKGALQEYQEKAAKLTAQKNDLENQLRDTQERLAQEEDARNQLFQTKKKLEQEIGSQKKD 654
Query: 2872 XXXXXXXXXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDH 3051
DK + D + + +L
Sbjct: 655 AEDLELQIQKIEQDKASKDHQIRNLNDEIAHQDELINKLNKEKKMQGEVNQKTAEELQAA 714
Query: 3052 EERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKV 3231
E++ H K K +LE L ELE L RE++ + ++E+ KRK+ +L+ +++ +A+
Sbjct: 715 EDKVNHLNKVKAKLEQTLDELEDSLEREKKLRGDVEKAKRKVEGDLKLTQEAVADLERNK 774
Query: 3232 EELNNQLMKRDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAE 3411
+EL ++++D+E+ + ++E + V +QKQ++++Q I+EL E++E ER AR KAE
Sbjct: 775 KELEQTVLRKDKEISALSAKLEDEQSLVGKLQKQIKELQARIEELEEEVEAERQARAKAE 834
Query: 3412 MTRREVVAQLEKVKGDVLDKVDEATMLQ-DLMSRKDEEVNATKRAIEQIQHTMEGKIEEQ 3588
R ++ +LE++ G+ L++ AT Q +L +++ E+ +R +E+ EG +
Sbjct: 835 KQRADLARELEEL-GERLEEAGGATSAQIELNKKREAELAKLRRDLEEANIQHEGTLANL 893
Query: 3589 KAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIH 3768
+ K + V E+ +Q++Q K +++ EK++ Q E D L +A +K K
Sbjct: 894 RKKHNDAVAEMAEQVDQLNKLKTKAEKERTQYFAELNDARIGCDQLSNEKAAQEKIAKQL 953
Query: 3769 EAHLMEIQANLAESDEHKRTLIDQLERSRDEL----DHLNRVREEEEHAFANMQRRLATA 3936
+ L E+Q+ L DE RTL D + S+ +L L R E+ E + + + +
Sbjct: 954 QHTLNEVQSKL---DETNRTLND-FDASKKKLSIENSDLLRQLEDAESQVSQLSKIKISL 1009
Query: 3937 XXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDE-KEEAEGLRAHLEKEIHAARQG 4113
R + + + R LE + + L ++ +EEAEG + +++++ A
Sbjct: 1010 TQQLEDTKRLADEEARERATLLGKFRNLEHDLDNLREQVEEEAEG-KGDIQRQLSKANAE 1068
Query: 4114 AGEARRKAEE---SVNQQLEELRKK---NLRDVEHLQKQLEESEVAKERILQSKKKIQQE 4275
A R K E + ++LEE ++K L + E + L + +A E+ +K+++ E
Sbjct: 1069 AQLWRSKYESEGVARAEELEEAKRKLQARLAEAEETIESLNQKCIALEK---TKQRLATE 1125
Query: 4276 LEDSSMELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRVLSL 4455
+ED +E++ + +EK+QK F+ + E ++ V + DA +E R+ T + L
Sbjct: 1126 VEDLQLEVDRASSIANAAEKKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELFRL 1185
Query: 4456 LNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMRVQM 4635
+ +E LE R ++L E++D + + G+N+HE+EK+++ LEAE ++++ +
Sbjct: 1186 KGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGRNIHEIEKSRKRLEAEKDELQAAL 1245
Query: 4636 EELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENELENE 4815
EE E L+ E+ LR ++ ++ E DR I K+ E E R+ + + ++ LE E
Sbjct: 1246 EEAEAALEQEENKVLRAQLELSQVRQEIDRRIQEKEEEFENTRKNHQRALDSMQASLEAE 1305
Query: 4816 KRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAK 4995
+GK+ A+ +KK+E I ELE L+ AN+ E + Q EE ++A+
Sbjct: 1306 AKGKAEALRMKKKLEADINELEIALDHANKANAEAQKNIKRYQQQLKDVQSALEEEQRAR 1365
Query: 4996 EDIAALLREADRKFRAVEAEREQ----LREANEGLMQARKQXXXXXXXXXXXRAKGGGIS 5163
+D L ++R+ A++ E E+ L +A+ G QA ++ A+ I+
Sbjct: 1366 DDAREQLGISERRANALQNELEESRTLLEQADRGRRQAEQELSDAHEQLNEVSAQNASIA 1425
Query: 5164 SEEKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEAEK 5343
+ KR+LE+++ + + + +K +KA V ++ +L E+ Q E +
Sbjct: 1426 A-AKRKLESELQTLHSDLDELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLR 1484
Query: 5344 QSLERSNRDYKAKITELESGAQSRARAQMAALEAKVQYLEDQLNVEGQEKTAANRAARRL 5523
++LE+ ++ + ++ E ES A + + LE +V+ LE +L+ E + A + R+
Sbjct: 1485 KALEQQIKELQVRLDEAESNALKGGKKAIQKLEQRVRELESELDSEQRRHADAQKNLRKS 1544
Query: 5524 EKRLNDTTQQFEDEKRANEQAKELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQR-- 5697
E+R+ + T Q E++++ +E+ ++L++K K + +RQ++EAE+ + K R Q+
Sbjct: 1545 ERRIKELTFQSEEDRKNHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQEL 1604
Query: 5698 -EADDLLDANEQ 5730
EA++ D EQ
Sbjct: 1605 EEAEERADIAEQ 1616
Score = 155 bits (391), Expect = 1e-35
Identities = 186/948 (19%), Positives = 398/948 (41%), Gaps = 60/948 (6%)
Frame = +1
Query: 3088 RLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMK--- 3258
+LE + + ++ +E + + ELE KLLAE D L+ + G ++E + K
Sbjct: 552 KLEEKATKAQEAYEKEEKLRKELEALNSKLLAEKTALLDSLSGEKGALQEYQEKAAKLTA 611
Query: 3259 RDEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQ 3438
+ +L++QL E A Q D + + + ++ +E E ++ K ++ Q
Sbjct: 612 QKNDLENQLRDTQERLA-------QEEDARNQLFQTKKKLEQEIGSQKK---DAEDLELQ 661
Query: 3439 LEKVKGDVLDKVDEATMLQDLMSRKDEEVN-----------ATKRAIEQIQHTME--GKI 3579
++K++ D K + L D ++ +DE +N ++ E++Q + +
Sbjct: 662 IQKIEQDKASKDHQIRNLNDEIAHQDELINKLNKEKKMQGEVNQKTAEELQAAEDKVNHL 721
Query: 3580 EEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKR 3759
+ KAK + ++EL D +E+ KK R +EK + + + + + L Q + AD+++ +
Sbjct: 722 NKVKAKLEQTLDELEDSLEREKKLRGDVEKAKRKVEGD-------LKLTQEAVADLERNK 774
Query: 3760 KIHEAHLM----EIQANLAESDEHKRTLIDQLERSRDELDHLNRVREEEEHAFANMQRRL 3927
K E ++ EI A L+ E +++L+ +L++ EL R+ E EE A Q R
Sbjct: 775 KELEQTVLRKDKEISA-LSAKLEDEQSLVGKLQKQIKELQA--RIEELEEEVEAERQAR- 830
Query: 3928 ATAXXXXXXXXXXXXXXTRLKIANINRARQLEDEKNALLDEKEEAEGLRAHLEKEIHAAR 4107
+ + + AR+LE+ L E+ E G + E++ R
Sbjct: 831 -----------------AKAEKQRADLARELEE-----LGERLEEAGGATSAQIELNKKR 868
Query: 4108 QGAGEARRKAEESVNQQ----LEELRKKNLRDVEHLQKQLEESEVAKERILQSKKKIQQE 4275
+ R+ E N Q L LRKK+ V + +Q+++ K + + + + E
Sbjct: 869 EAELAKLRRDLEEANIQHEGTLANLRKKHNDAVAEMAEQVDQLNKLKTKAEKERTQYFAE 928
Query: 4276 LEDSSM---ELENVRASHRDSEKRQKKFESQMAEERVAVQKALLDRDAMSQELRDRETRV 4446
L D+ + +L N +A+ K+ + +++ + + L D DA ++L +
Sbjct: 929 LNDARIGCDQLSNEKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSIENS-- 986
Query: 4447 LSLLNEVDIMKEHLEESDRVRRSLQQELQDSISNKDDFGKNVHELEKAKRSLEAELNDMR 4626
LL +++ + + + +++ SL Q+L+D+ D+ + L R+LE +L+++R
Sbjct: 987 -DLLRQLEDAESQVSQLSKIKISLTQQLEDTKRLADEEARERATLLGKFRNLEHDLDNLR 1045
Query: 4627 VQMEELEDNLQIAEDARLRLEVTNQALKSESDRAISNKDVEAEEKRRGLLKQIRDLENEL 4806
Q+EE + + + Q +S+ + + E EE +R L ++ + E +
Sbjct: 1046 EQVEEEAEGKGDIQRQLSKANAEAQLWRSKYESEGVARAEELEEAKRKLQARLAEAEETI 1105
Query: 4807 ENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEEYXXXXXXXXXXXXEYQIECEEAR 4986
E+ + ++++ ++ +L+ +++ A+ + E++++ ++
Sbjct: 1106 ESLNQKCIALEKTKQRLATEVEDLQLEVDRASSIANAAEKKQKAFDKIIGEWKLKVDDLA 1165
Query: 4987 QAKEDIAALLREADRKFRAVEAEREQLREANEGLMQARKQXXXXXXXXXXXRAKGGGISS 5166
+ R + ++ E+ +E E + + K +GG
Sbjct: 1166 AELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGRNIH 1225
Query: 5167 E---EKRRLEAKIAQXXXXXXXXQSNCELAIDKQRKAQVQLEQITTDLSMERTLNQKTEA 5337
E ++RLEA+ + ++ E +K +AQ++L Q+ ++ +R + +K E
Sbjct: 1226 EIEKSRKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEI--DRRIQEKEEE 1283
Query: 5338 EKQSLERSNRDYKAKITELESGAQSRARA--QMAALEAKVQYLEDQLNVEGQEKTAANRA 5511
+ + + R + LE+ A+ +A A LEA + LE L+ + A +
Sbjct: 1284 FENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQKN 1343
Query: 5512 ARRLEKRLNDTTQQFEDEKR----------------------------ANEQAKELLEKS 5607
+R +++L D E+E+R EQA ++
Sbjct: 1344 IKRYQQQLKDVQSALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRRQA 1403
Query: 5608 NLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRELMN 5751
+ + QL+E + + R ++ E L ++L E N
Sbjct: 1404 EQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDELLNEAKN 1451
Score = 109 bits (272), Expect = 9e-22
Identities = 138/637 (21%), Positives = 266/637 (41%), Gaps = 88/637 (13%)
Frame = +1
Query: 3028 LTTQLLDHEERAKHGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDH 3207
L QL D E + K K L QL + ++ + E + ++ L R L +L++ ++
Sbjct: 988 LLRQLEDAESQVSQLSKIKISLTQQLEDTKRLADEEARERATLLGKFRNLEHDLDNLREQ 1047
Query: 3208 LAEKMGKVEELNNQLMKRDEELQHQLTRYDEES-ANVTLMQKQMRDMQTTIDELREDMET 3384
+ E+ ++ QL K + E Q ++Y+ E A +++ R +Q + E E +E+
Sbjct: 1048 VEEEAEGKGDIQRQLSKANAEAQLWRSKYESEGVARAEELEEAKRKLQARLAEAEETIES 1107
Query: 3385 ERNARNKAEMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRK----DEEVNATKRAIEQ 3552
E T++ + ++E D+ +VD A+ + + +K D+ + K ++
Sbjct: 1108 LNQKCIALEKTKQRLATEVE----DLQLEVDRASSIANAAEKKQKAFDKIIGEWKLKVDD 1163
Query: 3553 IQHTMEGKIEEQKAKFSRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQA 3732
+ ++ +E + +S ++ L E+ ++Q + ++ E D+ +I
Sbjct: 1164 LAAELDASQKECR-NYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGR 1222
Query: 3733 SRADIDKKRKIHEAHLMEIQANLAESD-----EHKRTLIDQLERS--RDELDHLNRVREE 3891
+ +I+K RK EA E+QA L E++ E + L QLE S R E+D + +EE
Sbjct: 1223 NIHEIEKSRKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEIDRRIQEKEE 1282
Query: 3892 E-EHAFANMQRRLATAXXXXXXXXXXXXXXTRLKI---ANINRARQLEDEKNALLDE--- 4050
E E+ N QR L + R+K A+IN D N E
Sbjct: 1283 EFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQK 1342
Query: 4051 -----KEEAEGLRAHLEKEIHA---ARQGAGEARRKAEESVNQ---------QLEELRKK 4179
+++ + +++ LE+E A AR+ G + R+A N+ Q + R++
Sbjct: 1343 NIKRYQQQLKDVQSALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRRQ 1402
Query: 4180 NLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKF--- 4350
+++ +QL E I +K+K++ EL+ +L+ + ++SE++ KK
Sbjct: 1403 AEQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDELLNEAKNSEEKAKKAMVD 1462
Query: 4351 ------ESQMAEERVAVQKALLDRDAMSQELRDR----------------------ETRV 4446
E + ++ Q+ L R A+ Q++++ E RV
Sbjct: 1463 AARLADELRAEQDHAQTQEKL--RKALEQQIKELQVRLDEAESNALKGGKKAIQKLEQRV 1520
Query: 4447 LSLLNEVDI-MKEHLE-------------------ESDRVRRSLQQELQDSISNK-DDFG 4563
L +E+D + H + E DR Q+L D + K +
Sbjct: 1521 RELESELDSEQRRHADAQKNLRKSERRIKELTFQSEEDRKNHERMQDLVDKLQQKIKTYK 1580
Query: 4564 KNVHELEKAKRSLEAELNDMRVQMEELEDNLQIAEDA 4674
+ + E E+ A+ + ++EE E+ IAE A
Sbjct: 1581 RQIEEAEEIAALNLAKFRKAQQELEEAEERADIAEQA 1617
Score = 89.7 bits (221), Expect = 8e-16
Identities = 111/532 (20%), Positives = 233/532 (42%), Gaps = 11/532 (2%)
Frame = +1
Query: 4180 NLRDVEHLQKQLEESEVAKERILQSKKKIQQELEDSSMELENVRASHRDSEKRQKKFESQ 4359
N+ VE +LEE + + ++K+++ELE + +L + + DS +K
Sbjct: 542 NVSRVEDQIAKLEEKATKAQEAYEKEEKLRKELEALNSKLLAEKTALLDSLSGEK---GA 598
Query: 4360 MAEERVAVQKALLDRDAMSQELRDRETRVLSLLNEVDIMKEHLEESDRVRRSLQQELQDS 4539
+ E + K ++ + +LRD + R L E D + + ++ L+QE+
Sbjct: 599 LQEYQEKAAKLTAQKNDLENQLRDTQER---LAQEEDARNQLFQ----TKKKLEQEIGSQ 651
Query: 4540 ISNKDDFGKNVHELEKAKRSLEAE---LNDMRVQMEELEDNLQIAEDARLRLEVTNQALK 4710
+ +D + ++E+ K S + + LND +EL + L ++ +++ EV +
Sbjct: 652 KKDAEDLELQIQKIEQDKASKDHQIRNLNDEIAHQDELINKLN--KEKKMQGEVNQKT-- 707
Query: 4711 SESDRAISNKDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQL 4890
+E +A +K + + L + + +LE+ LE EK+ + ++K+E + ++ +
Sbjct: 708 AEELQAAEDKVNHLNKVKAKLEQTLDELEDSLEREKKLRGDVEKAKRKVEGDLKLTQEAV 767
Query: 4891 EVANRLKEEYXXXXXXXXXXXXEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLR 5070
R K+E + +I A+ ED +L+ + ++ + ++A E+L
Sbjct: 768 ADLERNKKELEQTVLRK-----DKEISALSAKL--EDEQSLVGKLQKQIKELQARIEELE 820
Query: 5071 EANEGLMQARKQXXXXXXXXXXXRAKGGGISSEEKRRLEAKIAQXXXXXXXXQSNCELAI 5250
E E QAR AK ++ R LE + + EL
Sbjct: 821 EEVEAERQAR--------------AKAEKQRADLARELEELGERLEEAGGATSAQIEL-- 864
Query: 5251 DKQRKAQVQLEQITTDLSMERTLNQKTEAEKQSLERSNRDYKAKITE-------LESGAQ 5409
+K + +L ++ DL ++ T A +L + + D A++ E L++ A+
Sbjct: 865 --NKKREAELAKLRRDLEEANIQHEGTLA---NLRKKHNDAVAEMAEQVDQLNKLKTKAE 919
Query: 5410 SRARAQMAAL-EAKVQYLEDQLNVEGQEKTAANRAARRLEKRLNDTTQQFEDEKRANEQA 5586
A L +A++ DQL+ EK A + A++L+ LN+ + ++ R
Sbjct: 920 KERTQYFAELNDARIGC--DQLS---NEKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDF 974
Query: 5587 KELLEKSNLKNRNLRRQLDEAEDEMSRERTKHRNVQREADDLLDANEQLTRE 5742
+K +++N +L RQL++AE ++S+ ++ ++ +D ++ RE
Sbjct: 975 DASKKKLSIENSDLLRQLEDAESQVSQLSKIKISLTQQLEDTKRLADEEARE 1026
Score = 79.7 bits (195), Expect = 8e-13
Identities = 81/418 (19%), Positives = 183/418 (43%), Gaps = 25/418 (5%)
Frame = +1
Query: 3091 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 3270
L +Q+ E ++++ + + LE K +L A LE+++ L ++ KV +L + +E
Sbjct: 1213 LLDQIGEGGRNIHEIEKSRKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQE 1272
Query: 3271 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQLEKV 3450
+ ++ +EE N ++ Q +D ++ +E E + +A ++++ A + ++
Sbjct: 1273 IDRRIQEKEEEFENTR------KNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINEL 1326
Query: 3451 KGDVLDKVDEATM-LQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQKAKFSRQVEELHD 3627
+ LD ++A Q + R +++ + A+E+ Q + EQ R+ L +
Sbjct: 1327 E-IALDHANKANAEAQKNIKRYQQQLKDVQSALEEEQRARDDA-REQLGISERRANALQN 1384
Query: 3628 QIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHLMEIQANL-- 3801
++E+ + Q ++ + QA+QE +D +++ + A A I ++ E+ L + ++L
Sbjct: 1385 ELEESRTLLEQADRGRRQAEQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDE 1444
Query: 3802 ----AESDEHKRT--------LIDQLERSRDELDHLNRVREEEEHAFANMQRRLATAXXX 3945
A++ E K L D+L +D ++R+ E +Q RL A
Sbjct: 1445 LLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAESN 1504
Query: 3946 XXXXXXXXXXXTRLKIANIN------RARQLEDEKNALLDEKEEAE-GLRAHLEKEIHAA 4104
++ + + R + +KN E+ E ++ +++ H
Sbjct: 1505 ALKGGKKAIQKLEQRVRELESELDSEQRRHADAQKNLRKSERRIKELTFQSEEDRKNHER 1564
Query: 4105 RQGAGEARRKAEESVNQQLEELRK---KNLRDVEHLQKQLEESEVAKERILQSKKKIQ 4269
Q + ++ ++ +Q+EE + NL Q++LEE+E + Q+ K +
Sbjct: 1565 MQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADIAEQAATKFR 1622
Score = 53.9 bits (128), Expect = 5e-05
Identities = 62/408 (15%), Positives = 157/408 (38%), Gaps = 12/408 (2%)
Frame = +1
Query: 2533 QVTRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAE 2712
++ ++ + A+ DEL+A E + E + E K+ + +E + +++++ + + E
Sbjct: 1226 EIEKSRKRLEAEKDELQAALE---EAEAALEQEENKVLRAQLELSQVRQEIDRRIQEKEE 1282
Query: 2713 LDDIRGRLQTRNQELEYIVNDMRDRLSXXXXXXXXXXXXRRKQMETVRDXXXXXXXXXXX 2892
+ + + ++ M+ L ++K + +
Sbjct: 1283 ------EFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKA 1336
Query: 2893 XXXXXXDKTNVDQXXXXXXXXXXXXQDAYDXXXXXXXXXXXXXXGLTTQLLDHEERAKHG 3072
+ Q Q A D L +L + +
Sbjct: 1337 NAEAQKNIKRYQQQLKDVQSALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQA 1396
Query: 3073 VKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQL 3252
+ + + E +L + + LN + + KRKL +EL+ L E + + + +
Sbjct: 1397 DRGRRQAEQELSDAHEQLNEVSAQNASIAAAKRKLESELQTLHSDLDELLNEAKNSEEKA 1456
Query: 3253 MKR-------DEELQHQLTRYDEESANVTLMQKQMRDMQTTIDELRED-METERNARNKA 3408
K +EL+ + + +++Q++++Q +DE + ++ + A K
Sbjct: 1457 KKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAESNALKGGKKAIQKL 1516
Query: 3409 EMTRREVVAQLEKVKGDVLDKVDEATMLQDLMSRKDEEVNATKRAIEQIQHTMEGKIEEQ 3588
E RE+ ++L+ + D + + + ++ E++Q ++ K++++
Sbjct: 1517 EQRVRELESELDSEQRRHADAQKNLRKSERRIKELTFQSEEDRKNHERMQDLVD-KLQQK 1575
Query: 3589 KAKFSRQVEELHD----QIEQHKKQRSQLEKQQNQADQERADMAQEIA 3720
+ RQ+EE + + + +K + +LE+ + ERAD+A++ A
Sbjct: 1576 IKTYKRQIEEAEEIAALNLAKFRKAQQELEEAE-----ERADIAEQAA 1618
Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
Posted date: Aug 11, 2004 12:04 AM
Number of letters in database: 661,712,633
Number of sequences in database: 1,967,186
Lambda K H
0.315 0.131 0.353
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,943,300,331
Number of Sequences: 1967186
Number of extensions: 122070854
Number of successful extensions: 641424
Number of sequences better than 10.0: 16023
Number of HSP's better than 10.0 without gapping: 384716
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 564857
length of database: 661,712,633
effective HSP length: 141
effective length of database: 384,339,407
effective search space used: 700266399554
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)