Homology by BLASTX
BLASTX 2.2.4 [Aug-26-2002]
Query= F52H3_7
(2193 letters)
Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
1,967,186 sequences; 661,712,633 total letters
Score E
Sequences producing significant alignments: (bits) Value
gi|17535123|ref|NP_496170.1| procollagen-lysine precursor, LETha... 1483 0.0
gi|39587781|emb|CAE67799.1| Hypothetical protein CBG13377 [Caeno... 1365 0.0
gi|27696396|gb|AAH43893.1| Plod-prov protein [Xenopus laevis] 691 0.0
gi|12850403|dbj|BAB28704.1| unnamed protein product [Mus musculus] 679 0.0
gi|6755110|ref|NP_036092.1| procollagen-lysine, 2-oxoglutarate 5... 679 0.0
gi|30017429|ref|NP_835202.1| procollagen-lysine, 2-oxoglutarate ... 678 0.0
gi|4505891|ref|NP_001075.1| procollagen-lysine, 2-oxoglutarate 5... 668 0.0
gi|50759427|ref|XP_417641.1| PREDICTED: similar to procollagen-l... 647 0.0
gi|126651|sp|P24802|PLO1_CHICK Procollagen-lysine,2-oxoglutarate... 647 0.0
gi|31242367|ref|XP_321614.1| ENSANGP00000011729 [Anopheles gambi... 647 0.0
gi|50752229|ref|XP_422695.1| PREDICTED: similar to procollagen-l... 644 0.0
gi|16741721|gb|AAH16657.1| Lysyl hydroxylase, precursor [Homo sa... 638 0.0
gi|4505889|ref|NP_000926.1| procollagen-lysine, 2-oxoglutarate 5... 637 0.0
gi|16758678|ref|NP_446279.1| procollagen-lysine, 2-oxoglutarate ... 637 0.0
gi|24662591|ref|NP_648451.1| CG6199-PA [Drosophila melanogaster]... 637 0.0
gi|32307144|ref|NP_000293.2| lysyl hydroxylase precursor; lysine... 637 0.0
gi|400205|sp|Q02809|PLO1_HUMAN Procollagen-lysine,2-oxoglutarate... 637 0.0
gi|6755108|ref|NP_036091.1| procollagen lysine, 2-oxoglutarate 5... 634 e-180
gi|18204027|gb|AAH21352.1| Procollagen lysine, 2-oxoglutarate 5-... 632 e-180
gi|28400783|emb|CAD23630.1| procollagen-lysine, 2-oxoglutarate 5... 631 e-179
gi|6755106|ref|NP_035252.1| procollagen-lysine, 2-oxoglutarate 5... 628 e-178
gi|33636742|ref|NP_891988.1| procollagen-lysine, 2-oxoglutarate ... 627 e-178
gi|27806477|ref|NP_776573.1| procollagen-lysine, 2-oxoglutarate ... 625 e-177
gi|28557685|ref|NP_787065.1| procollagen lysine, 2-oxoglutarate ... 619 e-176
gi|27924281|gb|AAH45041.1| LOC398437 protein [Xenopus laevis] 613 e-174
gi|47210803|emb|CAF89795.1| unnamed protein product [Tetraodon n... 474 e-132
gi|47205471|emb|CAF94612.1| unnamed protein product [Tetraodon n... 436 e-121
gi|26343375|dbj|BAC35344.1| unnamed protein product [Mus musculus] 419 e-115
gi|28380952|gb|AAO41443.1| RE30068p [Drosophila melanogaster] 414 e-114
gi|7433176|pir||T08679 procollagen-lysine 5-dioxygenase (EC 1.14... 386 e-105
gi|16307441|gb|AAH10268.1| Plod1 protein [Mus musculus] 373 e-102
gi|47223418|emb|CAG04279.1| unnamed protein product [Tetraodon n... 342 2e-92
gi|21428536|gb|AAM49928.1| LD37702p [Drosophila melanogaster] 313 1e-83
gi|16877124|gb|AAH16834.1| Unknown (protein for IMAGE:3883264) [... 255 4e-66
gi|48143658|ref|XP_397456.1| similar to procollagen-lysine, 2-ox... 173 1e-41
gi|31239821|ref|XP_320324.1| ENSANGP00000014001 [Anopheles gambi... 89 3e-16
gi|47212320|emb|CAF91258.1| unnamed protein product [Tetraodon n... 77 1e-12
gi|48140785|ref|XP_397154.1| similar to hypothetical protein [Ap... 73 3e-11
gi|46195811|ref|NP_808424.2| expressed sequence AI427652 [Mus mu... 72 4e-11
gi|26343025|dbj|BAC35169.1| unnamed protein product [Mus musculus] 72 4e-11
gi|46447512|ref|YP_008877.1| putative procollagen-lysine 5-dioxy... 72 6e-11
gi|13470787|ref|NP_102356.1| hypothetical protein mll0582 [Mesor... 71 1e-10
gi|47188856|emb|CAG14621.1| unnamed protein product [Tetraodon n... 70 3e-10
gi|24581946|ref|NP_723087.1| CG31915-PA [Drosophila melanogaster... 69 6e-10
gi|16506820|ref|NP_055916.1| chromosome 1 open reading frame 17 ... 67 1e-09
gi|7513030|pir||T00343 hypothetical protein KIAA0584 - human (fr... 67 1e-09
gi|47206702|emb|CAF89946.1| unnamed protein product [Tetraodon n... 67 2e-09
gi|47213906|emb|CAF95848.1| unnamed protein product [Tetraodon n... 67 2e-09
gi|50751172|ref|XP_422290.1| PREDICTED: similar to chromosome 1 ... 65 5e-09
gi|47220022|emb|CAG12170.1| unnamed protein product [Tetraodon n... 60 2e-07
gi|47216930|emb|CAG04872.1| unnamed protein product [Tetraodon n... 59 6e-07
gi|34880483|ref|XP_222718.2| similar to chromosome 1 open readin... 58 1e-06
gi|34785210|gb|AAH56951.1| RIKEN cDNA 2810024B22 [Mus musculus] 57 1e-06
gi|22122765|ref|NP_666323.1| RIKEN cDNA 2810024B22 [Mus musculus... 57 1e-06
gi|25056451|ref|XP_130094.3| expressed sequence AL024097 [Mus mu... 57 2e-06
gi|46446818|ref|YP_008183.1| hypothetical protein pc1184 [Parach... 57 2e-06
gi|34877564|ref|XP_214295.2| similar to hypothetical protein MGC... 57 2e-06
gi|31377697|ref|NP_078932.2| hypothetical protein FLJ22329 [Homo... 55 7e-06
gi|47223918|emb|CAG06095.1| unnamed protein product [Tetraodon n... 54 1e-05
gi|18401806|ref|NP_566600.1| oxidoreductase, 2OG-Fe(II) oxygenas... 54 2e-05
gi|50757446|ref|XP_425340.1| PREDICTED: similar to cerebral endo... 54 2e-05
gi|22760716|dbj|BAC11307.1| unnamed protein product [Homo sapiens] 53 3e-05
gi|34853178|ref|XP_238320.2| similar to hypothetical protein MGC... 53 3e-05
gi|18700451|dbj|BAB85193.1| hypothetical protein [Bombyx mori] >... 52 5e-05
gi|47215341|emb|CAG12575.1| unnamed protein product [Tetraodon n... 52 5e-05
gi|34914494|ref|NP_918594.1| B1080D07.28 [Oryza sativa (japonica... 50 2e-04
gi|50756347|ref|XP_415123.1| PREDICTED: similar to hypothetical ... 49 5e-04
gi|23613815|ref|NP_704836.1| hypothetical protein [Plasmodium fa... 46 0.003
gi|7959265|dbj|BAA96026.1| KIAA1502 protein [Homo sapiens] 45 0.009
gi|21313390|ref|NP_079947.1| RIKEN cDNA 5730405M13 [Mus musculus... 45 0.009
gi|5764665|gb|AAD51367.1| cerebral cell adhesion molecule [Homo ... 45 0.009
gi|33620719|ref|NP_057258.2| cerebral endothelial cell adhesion ... 45 0.009
gi|26383072|dbj|BAC25517.1| unnamed protein product [Mus musculus] 45 0.009
gi|34872325|ref|XP_213776.2| similar to RIKEN cDNA 5730405M13 [R... 44 0.016
gi|13375846|ref|NP_078899.1| hypothetical protein FLJ13491 [Homo... 42 0.080
gi|34364724|emb|CAE45807.1| hypothetical protein [Homo sapiens] 41 0.10
gi|46434342|gb|EAK93754.1| hypothetical protein CaO19.4494 [Cand... 40 0.23
gi|27413327|gb|AAO11801.1| alpha-1,2-mannosyltransferase [Candid... 40 0.23
gi|50305947|ref|XP_452934.1| unnamed protein product [Kluyveromy... 39 0.40
gi|33241268|ref|NP_876210.1| Glycosyltransferase [Prochlorococcu... 38 0.88
gi|39580938|emb|CAE65568.1| Hypothetical protein CBG10562 [Caeno... 38 1.2
gi|46447003|ref|YP_008368.1| putative glycosyltransferase [Parac... 38 1.2
gi|34906198|ref|NP_914446.1| OJ1174_D05.17 [Oryza sativa (japoni... 38 1.2
gi|48865141|ref|ZP_00319005.1| COG3589: Uncharacterized conserve... 37 2.0
gi|48841391|ref|ZP_00298317.1| COG0463: Glycosyltransferases inv... 37 2.6
gi|46436203|gb|EAK95570.1| hypothetical protein CaO19.3204 [Cand... 36 3.4
gi|14601234|ref|NP_147767.1| hypothetical protein APE1184 [Aerop... 36 4.4
gi|15207893|dbj|BAB62971.1| hypothetical protein [Macaca fascicu... 36 4.4
gi|5702005|emb|CAB52238.1| EpsP protein [Streptococcus thermophi... 36 4.4
gi|15208149|dbj|BAB63099.1| hypothetical protein [Macaca fascicu... 36 4.4
gi|16805196|ref|NP_473224.1| hypothetical protein [Plasmodium fa... 35 5.7
gi|21389491|ref|NP_653314.1| hypothetical protein FLJ32954 [Homo... 35 5.7
gi|15080796|gb|AAK77978.1| enolase [Dendroctonus murrayanae] 35 5.7
gi|30022017|ref|NP_833648.1| Phosphopantetheine adenylyltransfer... 35 5.7
gi|42453515|ref|ZP_00153422.1| hypothetical protein Rick036701 [... 35 7.5
gi|15900002|ref|NP_344606.1| beta-N-acetylhexosaminidase [Strept... 35 7.5
gi|48857937|ref|ZP_00311911.1| COG0174: Glutamine synthetase [Cl... 35 7.5
gi|13541091|ref|NP_110779.1| Predicted phosphoribosyltransferase... 35 9.8
gi|26452083|dbj|BAC43131.1| unknown protein [Arabidopsis thaliana] 35 9.8
gi|42407704|dbj|BAD08852.1| unknown protein [Oryza sativa (japon... 35 9.8
gi|14324475|dbj|BAB59403.1| hypoxanthine-guanine phosphoribosylt... 35 9.8
gi|50302643|ref|XP_451257.1| unnamed protein product [Kluyveromy... 35 9.8
gi|21401981|ref|NP_657966.1| Cytidylyltransf, Cytidylyltransfera... 35 9.8
gi|47094008|ref|ZP_00231740.1| methyltransferase, putative [List... 35 9.8
gi|46908262|ref|YP_014651.1| methyltransferase, putative [Lister... 35 9.8
>gi|17535123|ref|NP_496170.1| procollagen-lysine precursor, LEThal
LET-268 (84.4 kD) (let-268) [Caenorhabditis elegans]
gi|6093732|sp|Q20679|PLOD_CAEEL Procollagen-lysine,2-oxoglutarate
5-dioxygenase precursor (Lysyl hydroxylase) (LH)
gi|7433177|pir||T22517 probable procollagen-lysine 5-dioxygenase (EC
1.14.11.4) - Caenorhabditis elegans
gi|3877389|emb|CAA91321.1| Hypothetical protein F52H3.1
[Caenorhabditis elegans]
Length = 730
Score = 1483 bits (3839), Expect = 0.0
Identities = 715/715 (100%), Positives = 715/715 (100%)
Frame = -1
Query: 2148 ATTITDLPELVVVTVATENTDGLKRLLESAKAFDINIEVLGLGEKWNGGDTRIEQGGGQK 1969
ATTITDLPELVVVTVATENTDGLKRLLESAKAFDINIEVLGLGEKWNGGDTRIEQGGGQK
Sbjct: 16 ATTITDLPELVVVTVATENTDGLKRLLESAKAFDINIEVLGLGEKWNGGDTRIEQGGGQK 75
Query: 1968 IRILSDWIEKYKDASDTMIMFVDAYDVVFNADSTTILRKFFEHYSEKRLLFGAEPFCWPD 1789
IRILSDWIEKYKDASDTMIMFVDAYDVVFNADSTTILRKFFEHYSEKRLLFGAEPFCWPD
Sbjct: 76 IRILSDWIEKYKDASDTMIMFVDAYDVVFNADSTTILRKFFEHYSEKRLLFGAEPFCWPD 135
Query: 1788 QSLAPEYPIVEFGKRFLNSGLFMGYGPEMHKILKLKSVEDKDDDQLYYTMIYLDEKLRKE 1609
QSLAPEYPIVEFGKRFLNSGLFMGYGPEMHKILKLKSVEDKDDDQLYYTMIYLDEKLRKE
Sbjct: 136 QSLAPEYPIVEFGKRFLNSGLFMGYGPEMHKILKLKSVEDKDDDQLYYTMIYLDEKLRKE 195
Query: 1608 LNMDLDSMSKIFQNLNGVIEDVELQFKEDGTPEAYNAAYNTKPLIVHGNGPSKSHLNYLG 1429
LNMDLDSMSKIFQNLNGVIEDVELQFKEDGTPEAYNAAYNTKPLIVHGNGPSKSHLNYLG
Sbjct: 196 LNMDLDSMSKIFQNLNGVIEDVELQFKEDGTPEAYNAAYNTKPLIVHGNGPSKSHLNYLG 255
Query: 1428 NYLGNRWNSQLGCRTCGLEVKESEEVPLIALNLFISKPIPFIEEVLQKIAEFDYPKEKIA 1249
NYLGNRWNSQLGCRTCGLEVKESEEVPLIALNLFISKPIPFIEEVLQKIAEFDYPKEKIA
Sbjct: 256 NYLGNRWNSQLGCRTCGLEVKESEEVPLIALNLFISKPIPFIEEVLQKIAEFDYPKEKIA 315
Query: 1248 LYIYNNQPFSIKNIQDFLQKHGKSYYTKRVINGVTEIGDREARNEAIEWNKARNVEFAFL 1069
LYIYNNQPFSIKNIQDFLQKHGKSYYTKRVINGVTEIGDREARNEAIEWNKARNVEFAFL
Sbjct: 316 LYIYNNQPFSIKNIQDFLQKHGKSYYTKRVINGVTEIGDREARNEAIEWNKARNVEFAFL 375
Query: 1068 MDGDAYFSEPKVIKDLIQYSKTYDVGIIAPMIGQPGKLFTNFWGAIAANGYYARSEDYMA 889
MDGDAYFSEPKVIKDLIQYSKTYDVGIIAPMIGQPGKLFTNFWGAIAANGYYARSEDYMA
Sbjct: 376 MDGDAYFSEPKVIKDLIQYSKTYDVGIIAPMIGQPGKLFTNFWGAIAANGYYARSEDYMA 435
Query: 888 IVKGNRVGYWNVPFITSAVLFNKEKLEAMKDAYSYNKNLDPDMSMCKFARDNGHFLYIDN 709
IVKGNRVGYWNVPFITSAVLFNKEKLEAMKDAYSYNKNLDPDMSMCKFARDNGHFLYIDN
Sbjct: 436 IVKGNRVGYWNVPFITSAVLFNKEKLEAMKDAYSYNKNLDPDMSMCKFARDNGHFLYIDN 495
Query: 708 EKYYGFLIVSDEYAETVTEGKWHPEMWQIFENRELWEARYIHPGYHKIMEPEHVVDQACP 529
EKYYGFLIVSDEYAETVTEGKWHPEMWQIFENRELWEARYIHPGYHKIMEPEHVVDQACP
Sbjct: 496 EKYYGFLIVSDEYAETVTEGKWHPEMWQIFENRELWEARYIHPGYHKIMEPEHVVDQACP 555
Query: 528 DVYDFPLMSERFCEELIEEMEGFGRWSDGSNNDKRLAGGYENVPTRDIHMNQVGFERQWL 349
DVYDFPLMSERFCEELIEEMEGFGRWSDGSNNDKRLAGGYENVPTRDIHMNQVGFERQWL
Sbjct: 556 DVYDFPLMSERFCEELIEEMEGFGRWSDGSNNDKRLAGGYENVPTRDIHMNQVGFERQWL 615
Query: 348 YFMDTYVRPVQEKTFIGYYHQPVESNMMFVVRYKPEEQPSLRPHHDASTFSIDIALNKKG 169
YFMDTYVRPVQEKTFIGYYHQPVESNMMFVVRYKPEEQPSLRPHHDASTFSIDIALNKKG
Sbjct: 616 YFMDTYVRPVQEKTFIGYYHQPVESNMMFVVRYKPEEQPSLRPHHDASTFSIDIALNKKG 675
Query: 168 RDYEGGGVRYIRYNCTVPADEVGYAMMFPGRLTHLHEGLATTKGTRYIMVSFINP 4
RDYEGGGVRYIRYNCTVPADEVGYAMMFPGRLTHLHEGLATTKGTRYIMVSFINP
Sbjct: 676 RDYEGGGVRYIRYNCTVPADEVGYAMMFPGRLTHLHEGLATTKGTRYIMVSFINP 730
>gi|39587781|emb|CAE67799.1| Hypothetical protein CBG13377
[Caenorhabditis briggsae]
Length = 733
Score = 1365 bits (3534), Expect = 0.0
Identities = 644/716 (89%), Positives = 686/716 (94%), Gaps = 1/716 (0%)
Frame = -1
Query: 2148 ATTITDLPELVVVTVATENTDGLKRLLESAKAFDINIEVLGLGEKWNGGDTRIEQGGGQK 1969
A +ITDLPELVVVTVATENTDGLKRLLESAKAFDINIEVLGLGEKWNGGDTR+E+GGGQK
Sbjct: 18 AVSITDLPELVVVTVATENTDGLKRLLESAKAFDINIEVLGLGEKWNGGDTRVEKGGGQK 77
Query: 1968 IRILSDWIEKYKDASDTMIMFVDAYDVVFNADSTTILRKFFEHYSEKRLLFGAEPFCWPD 1789
IRILS WIEKYKDASDT+IMFVDAYDVVFNADS IL+KF EHY K+LLFGAEPFCWPD
Sbjct: 78 IRILSKWIEKYKDASDTIIMFVDAYDVVFNADSKNILQKFLEHYPGKQLLFGAEPFCWPD 137
Query: 1788 QSLAPEYPIVEFGKRFLNSGLFMGYGPEMHKILKLKSVEDKDDDQLYYTMIYLDEKLRKE 1609
Q+LAP+YPIVEFGKRFLNSGLFMGYGP++HKIL LKSVEDKDDDQLYYTMIYLDEKLRKE
Sbjct: 138 QTLAPDYPIVEFGKRFLNSGLFMGYGPQVHKILTLKSVEDKDDDQLYYTMIYLDEKLRKE 197
Query: 1608 LNMDLDSMSKIFQNLNGVIEDVELQFKEDGTPEAYNAAYNTKPLIVHGNGPSKSHLNYLG 1429
LNMDLDSMSKIFQNLNGVIEDVELQFKEDGTPEAYNAAYNTKPLIVHGNGPSKSHLNYLG
Sbjct: 198 LNMDLDSMSKIFQNLNGVIEDVELQFKEDGTPEAYNAAYNTKPLIVHGNGPSKSHLNYLG 257
Query: 1428 NYLGNRWNSQLGCRTCGLE-VKESEEVPLIALNLFISKPIPFIEEVLQKIAEFDYPKEKI 1252
NYLGNRWNSQLGCRTC E KE E PLI LNLFISKP+PFIEEVLQK++EFDYPK +I
Sbjct: 258 NYLGNRWNSQLGCRTCDQEGAKEQTEFPLIGLNLFISKPVPFIEEVLQKVSEFDYPKNRI 317
Query: 1251 ALYIYNNQPFSIKNIQDFLQKHGKSYYTKRVINGVTEIGDREARNEAIEWNKARNVEFAF 1072
ALYIYNNQPFSIKNIQDFL+ HGKSYYTKR+INGVTEIG+R+ARNEAI+W K R+ EFAF
Sbjct: 318 ALYIYNNQPFSIKNIQDFLKDHGKSYYTKRIINGVTEIGERQARNEAIDWCKQRDTEFAF 377
Query: 1071 LMDGDAYFSEPKVIKDLIQYSKTYDVGIIAPMIGQPGKLFTNFWGAIAANGYYARSEDYM 892
MDGDAYF+EP VIKDLI YSK+YDVGII+PM+GQPGKLFTNFWGAIAANGYYARSEDYM
Sbjct: 378 FMDGDAYFTEPTVIKDLIHYSKSYDVGIISPMVGQPGKLFTNFWGAIAANGYYARSEDYM 437
Query: 891 AIVKGNRVGYWNVPFITSAVLFNKEKLEAMKDAYSYNKNLDPDMSMCKFARDNGHFLYID 712
AIVKGNRVGYWNVPF+TSA+L +KEKL AM AY+YNKNLDPDMS+C+FARDNGHF+YI+
Sbjct: 438 AIVKGNRVGYWNVPFVTSALLMSKEKLGAMSGAYTYNKNLDPDMSLCQFARDNGHFMYIN 497
Query: 711 NEKYYGFLIVSDEYAETVTEGKWHPEMWQIFENRELWEARYIHPGYHKIMEPEHVVDQAC 532
NEKY+G+LIVSDE++ETVTEGKWHPEMWQIFENRELWEARYIHPGYHKIMEP+H++DQAC
Sbjct: 498 NEKYFGYLIVSDEFSETVTEGKWHPEMWQIFENRELWEARYIHPGYHKIMEPDHIIDQAC 557
Query: 531 PDVYDFPLMSERFCEELIEEMEGFGRWSDGSNNDKRLAGGYENVPTRDIHMNQVGFERQW 352
PDVYD+PLMSERFCEELIEEMEGFGRWSDGSNNDKRLAGGYENVPTRDIHMNQVGFERQW
Sbjct: 558 PDVYDYPLMSERFCEELIEEMEGFGRWSDGSNNDKRLAGGYENVPTRDIHMNQVGFERQW 617
Query: 351 LYFMDTYVRPVQEKTFIGYYHQPVESNMMFVVRYKPEEQPSLRPHHDASTFSIDIALNKK 172
LYF+DTYVRPVQEKTFIGYYHQPVESNMMFVVRYKPEEQ SLRPHHDASTFSIDIALNKK
Sbjct: 618 LYFLDTYVRPVQEKTFIGYYHQPVESNMMFVVRYKPEEQASLRPHHDASTFSIDIALNKK 677
Query: 171 GRDYEGGGVRYIRYNCTVPADEVGYAMMFPGRLTHLHEGLATTKGTRYIMVSFINP 4
GRDYEGGGVRY+RYNCTV ADEVGYAMMFPGRLTHLHEGLATTKGTRYIMVSFINP
Sbjct: 678 GRDYEGGGVRYVRYNCTVEADEVGYAMMFPGRLTHLHEGLATTKGTRYIMVSFINP 733
>gi|27696396|gb|AAH43893.1| Plod-prov protein [Xenopus laevis]
Length = 733
Score = 691 bits (1782), Expect = 0.0
Identities = 340/721 (47%), Positives = 481/721 (66%), Gaps = 14/721 (1%)
Frame = -1
Query: 2124 ELVVVTVATENTDGLKRLLESAKAFDINIEVLGLGEKWNGGDTRIEQGGGQKIRILSDWI 1945
+L+VVTVATE T+G R L +A+ F+ + LGLG +W GGD GGGQK+R L +
Sbjct: 32 KLLVVTVATEATEGYLRFLRTARHFNYTVRTLGLGHEWKGGDVARTVGGGQKVRWLKHEL 91
Query: 1944 EKYKDASDTMIMFVDAYDVVFNADSTTILRKF--FEHYSEKRLLFGAEPFCWPDQSLAPE 1771
E++KD D +IMFVD+YDVV + T +L KF FEH +++F AE FCWP+ SLA
Sbjct: 92 EQHKDQDDLIIMFVDSYDVVISGSPTELLWKFQRFEH----KVVFSAEGFCWPEWSLAES 147
Query: 1770 YPIVEFGKRFLNSGLFMGYGPEMHKILKLKSVEDKDDDQLYYTMIYLDEKLRKELNMDLD 1591
YP + GKRFLNSG F+G+ P+++++++L +D DDDQL+YT IYLDE +R++ ++ LD
Sbjct: 148 YPPITNGKRFLNSGGFIGFAPQLYQMVQLWKYKDNDDDQLFYTKIYLDESMREKFDITLD 207
Query: 1590 SMSKIFQNLNGVIEDVELQFKEDGTPEAYNAAYNTKPLIVHGNGPSKSHLNYLGNYLGNR 1411
S IFQNLNG I++V L+F E A N AY+T P+++HGNGP+K LNYLGNY+ N
Sbjct: 208 HKSNIFQNLNGAIDEVVLKF-ESNKVRARNVAYDTIPVVIHGNGPTKLQLNYLGNYVPNS 266
Query: 1410 WNSQLGCRTCG-----LEVKESEEVPLIALNLFISKPIPFIEEVLQKIAEFDYPKEKIAL 1246
W + GC C L + E + +P + L +FI +P PFI + LQ++ + DYP+ +++L
Sbjct: 267 WTHEGGCEVCDDDLLDLSMLEDDALPHVLLGVFIEQPTPFIPQFLQRLVQLDYPRNRLSL 326
Query: 1245 YIYNNQPFSIKNIQDFLQKHGKSYYTKRVINGVTEIGDREARNEAIEW-NKARNVEFAFL 1069
YI+N++ + ++I+ F +K+ S+ + +++ + EAR+ ++ + + ++ F
Sbjct: 327 YIHNSEVYHERHIEVFYKKYKDSFTSIKIVGPEEAMSQGEARDMGMDLCRQDQTCDYYFS 386
Query: 1068 MDGDAYFSEPKVIKDLIQYSKTYDVGIIAPMIGQPGKLFTNFWGAIAANGYYARSEDYMA 889
+D D + P + LIQ +K +IAPM+ + GKL++NFWGA++ GYYARSEDY+
Sbjct: 387 VDADVALTNPDTLYILIQENKK----VIAPMVSRSGKLWSNFWGALSPEGYYARSEDYVD 442
Query: 888 IVKGNRVGYWNVPFITSAVLFNKEKLEAMKDAYSYNKNL------DPDMSMCKFARDNGH 727
IV+ R G WNVP+I L E L A NKN+ DPDMS+CK RD
Sbjct: 443 IVQAKRAGVWNVPYIAHVYLIKGETLRAELS----NKNIFTLPQMDPDMSVCKSIRDKNV 498
Query: 726 FLYIDNEKYYGFLIVSDEYAETVTEGKWHPEMWQIFENRELWEARYIHPGYHKIMEPEHV 547
FL+I N +G L+ + +Y + H ++WQIFEN W+ +YIH Y KI E ++
Sbjct: 499 FLHISNRDEFGRLLSTSKY----NTSRLHNDLWQIFENPVDWKEKYIHENYSKIFEEDYY 554
Query: 546 VDQACPDVYDFPLMSERFCEELIEEMEGFGRWSDGSNNDKRLAGGYENVPTRDIHMNQVG 367
Q CPDVY FP+ SE C+E +EEME FG+WS G N D+RLAGGYENVPT DIHM Q+G
Sbjct: 555 -QQPCPDVYWFPVFSEVMCDEFVEEMENFGQWSGGKNQDQRLAGGYENVPTVDIHMTQIG 613
Query: 366 FERQWLYFMDTYVRPVQEKTFIGYYHQPVESNMMFVVRYKPEEQPSLRPHHDASTFSIDI 187
++ +WL F+ Y+ PV EK F GYY + ++ + F+VRY+P+EQPSLRPHHD+STF+++I
Sbjct: 614 YQEEWLKFLQEYIAPVTEKLFPGYYTK-AKALLNFIVRYRPDEQPSLRPHHDSSTFTVNI 672
Query: 186 ALNKKGRDYEGGGVRYIRYNCTVPADEVGYAMMFPGRLTHLHEGLATTKGTRYIMVSFIN 7
ALN KG DYEGGG R++RYNC V + G++ M PGRLTH HEGL TT+GTRYIMVSF++
Sbjct: 673 ALNNKGIDYEGGGCRFLRYNCRVESPRKGWSFMHPGRLTHYHEGLPTTRGTRYIMVSFVD 732
Query: 6 P 4
P
Sbjct: 733 P 733
>gi|12850403|dbj|BAB28704.1| unnamed protein product [Mus musculus]
Length = 741
Score = 679 bits (1751), Expect = 0.0
Identities = 330/714 (46%), Positives = 478/714 (66%), Gaps = 7/714 (0%)
Frame = -1
Query: 2124 ELVVVTVATENTDGLKRLLESAKAFDINIEVLGLGEKWNGGDTRIEQGGGQKIRILSDWI 1945
+L+V+TVAT T+G +R L+SA+ F+ + LGLG++W GGD GGGQK+R L +
Sbjct: 41 KLLVITVATAETEGYRRFLQSAEFFNYTVRTLGLGQEWRGGDVARTVGGGQKVRWLKKEM 100
Query: 1944 EKYKDASDTMIMFVDAYDVVFNADSTTILRKFFEHYSEKRLLFGAEPFCWPDQSLAPEYP 1765
EKY D D +IMFVD+YDV+ + T +L+KF + S LLF AE FCWP+ LA +YP
Sbjct: 101 EKYADQKDMIIMFVDSYDVILASSPTELLKKFVQ--SGSHLLFSAESFCWPEWGLAEQYP 158
Query: 1764 IVEFGKRFLNSGLFMGYGPEMHKILKLKSVEDKDDDQLYYTMIYLDEKLRKELNMDLDSM 1585
V GKRFLNSG F+G+ P +H+I++ + +D DDDQL+YT +YLD LR++L + LD
Sbjct: 159 EVGMGKRFLNSGGFIGFAPTIHQIVRQWNYKDDDDDQLFYTQLYLDPGLREKLKLSLDHK 218
Query: 1584 SKIFQNLNGVIEDVELQFKEDGTPEAYNAAYNTKPLIVHGNGPSKSHLNYLGNYLGNRWN 1405
S+IFQNLNG +++V L+F ++ N AY+T P++VHGNGP+K LNYLGNY+ N W
Sbjct: 219 SRIFQNLNGALDEVILKFDQNRV-RIRNVAYDTLPVVVHGNGPTKLQLNYLGNYVPNGWT 277
Query: 1404 SQLGCRTCGLEVKE---SEEVPLIALNLFISKPIPFIEEVLQKIAEFDYPKEKIALYIYN 1234
Q GC C ++ + P + L +F+ +P PF+ LQ++ DYP ++I+L+++N
Sbjct: 278 PQGGCGFCNQTLRTLPGGQPPPRVLLAVFVEQPTPFLPRFLQRLLLLDYPPDRISLFLHN 337
Query: 1233 NQPFSIKNIQDFLQKHGKSYYTKRVINGVTEIGDREARNEAIEWNKAR-NVEFAFLMDGD 1057
++ + +I D + + +++ + EAR+ A++ + EF F +D D
Sbjct: 338 SEVYHEPHIADAWPQLQDHFSAVKLVGPEEALSAGEARDMAMDSCRQNPECEFYFSLDAD 397
Query: 1056 AYFSEPKVIKDLIQYSKTYDVGIIAPMIGQPGKLFTNFWGAIAANGYYARSEDYMAIVKG 877
A + P+ ++ LI+ ++ +IAPM+ + GKL++NFWGA++ N YYARSEDY+ +V+
Sbjct: 398 AVLTNPETLRVLIEQNRK----VIAPMLSRHGKLWSNFWGALSPNEYYARSEDYVELVQR 453
Query: 876 NRVGYWNVPFITSAVLFNKEKLEA---MKDAYSYNKNLDPDMSMCKFARDNGHFLYIDNE 706
RVG WNVP+I+ A + E L K+ +S + + DPDM+ CK RD G FL++ N+
Sbjct: 454 KRVGVWNVPYISQAYVIRGETLRTELPQKEVFS-SSDTDPDMAFCKSVRDKGIFLHLSNQ 512
Query: 705 KYYGFLIVSDEYAETVTEGKWHPEMWQIFENRELWEARYIHPGYHKIMEPEHVVDQACPD 526
+G L+ + Y HP++WQIF+N W +YIH Y + ++ E +V+Q CPD
Sbjct: 513 HEFGRLLATSRY----DTDHLHPDLWQIFDNPVDWREQYIHENYSRALDGEGLVEQPCPD 568
Query: 525 VYDFPLMSERFCEELIEEMEGFGRWSDGSNNDKRLAGGYENVPTRDIHMNQVGFERQWLY 346
VY FPL++E+ C+EL+EEME +G+WS G + D RLAGGYENVPT DIHM QVG+E QWL
Sbjct: 569 VYWFPLLTEQMCDELVEEMEHYGQWSGGRHEDSRLAGGYENVPTVDIHMKQVGYEDQWLQ 628
Query: 345 FMDTYVRPVQEKTFIGYYHQPVESNMMFVVRYKPEEQPSLRPHHDASTFSIDIALNKKGR 166
+ TYV P+ E F G YH + M FVVRY+P+EQPSLRPHHD+STF++++ALN KG
Sbjct: 629 LLRTYVGPMTEYLFPG-YHTKTRAVMNFVVRYRPDEQPSLRPHHDSSTFTLNVALNHKGV 687
Query: 165 DYEGGGVRYIRYNCTVPADEVGYAMMFPGRLTHLHEGLATTKGTRYIMVSFINP 4
DYEGGG R++RY+C + + G+A++ PGRLTH HEGL TT+GTRYIMVSF++P
Sbjct: 688 DYEGGGCRFLRYDCRISSPRKGWALLHPGRLTHYHEGLPTTRGTRYIMVSFVDP 741
>gi|6755110|ref|NP_036092.1| procollagen-lysine, 2-oxoglutarate
5-dioxygenase 3; lysyl hydroxylase 2; lysyl hydroxylase 3
[Mus musculus]
gi|25008937|sp|Q9R0E1|PLO3_MOUSE Procollagen-lysine,2-oxoglutarate
5-dioxygenase 3 precursor (Lysyl hydroxylase 3) (LH3)
gi|5880317|gb|AAD54618.1| lysyl hydroxylase 3 [Mus musculus]
gi|15145782|gb|AAK00576.1| lysyl hydroxylase 3 [Mus musculus]
gi|26329015|dbj|BAC28246.1| unnamed protein product [Mus musculus]
gi|26354078|dbj|BAC40669.1| unnamed protein product [Mus musculus]
gi|28175483|gb|AAH43047.1| Procollagen-lysine, 2-oxoglutarate
5-dioxygenase 3 [Mus musculus]
gi|32493408|gb|AAH54734.1| Procollagen-lysine, 2-oxoglutarate
5-dioxygenase 3 [Mus musculus]
Length = 741
Score = 679 bits (1751), Expect = 0.0
Identities = 330/714 (46%), Positives = 478/714 (66%), Gaps = 7/714 (0%)
Frame = -1
Query: 2124 ELVVVTVATENTDGLKRLLESAKAFDINIEVLGLGEKWNGGDTRIEQGGGQKIRILSDWI 1945
+L+V+TVAT T+G +R L+SA+ F+ + LGLG++W GGD GGGQK+R L +
Sbjct: 41 KLLVITVATAETEGYRRFLQSAEFFNYTVRTLGLGQEWRGGDVARTVGGGQKVRWLKKEM 100
Query: 1944 EKYKDASDTMIMFVDAYDVVFNADSTTILRKFFEHYSEKRLLFGAEPFCWPDQSLAPEYP 1765
EKY D D +IMFVD+YDV+ + T +L+KF + S LLF AE FCWP+ LA +YP
Sbjct: 101 EKYADQKDMIIMFVDSYDVILASSPTELLKKFVQ--SGSHLLFSAESFCWPEWGLAEQYP 158
Query: 1764 IVEFGKRFLNSGLFMGYGPEMHKILKLKSVEDKDDDQLYYTMIYLDEKLRKELNMDLDSM 1585
V GKRFLNSG F+G+ P +H+I++ + +D DDDQL+YT +YLD LR++L + LD
Sbjct: 159 EVGMGKRFLNSGGFIGFAPTIHQIVRQWNYKDDDDDQLFYTQLYLDPGLREKLKLSLDHK 218
Query: 1584 SKIFQNLNGVIEDVELQFKEDGTPEAYNAAYNTKPLIVHGNGPSKSHLNYLGNYLGNRWN 1405
S+IFQNLNG +++V L+F ++ N AY+T P++VHGNGP+K LNYLGNY+ N W
Sbjct: 219 SRIFQNLNGALDEVILKFDQNRV-RIRNVAYDTLPVVVHGNGPTKLQLNYLGNYVPNGWT 277
Query: 1404 SQLGCRTCGLEVKE---SEEVPLIALNLFISKPIPFIEEVLQKIAEFDYPKEKIALYIYN 1234
Q GC C ++ + P + L +F+ +P PF+ LQ++ DYP ++I+L+++N
Sbjct: 278 PQGGCGFCNQTLRTLPGGQPPPRVLLAVFVEQPTPFLPRFLQRLLLLDYPPDRISLFLHN 337
Query: 1233 NQPFSIKNIQDFLQKHGKSYYTKRVINGVTEIGDREARNEAIEWNKAR-NVEFAFLMDGD 1057
++ + +I D + + +++ + EAR+ A++ + EF F +D D
Sbjct: 338 SEVYHEPHIADAWPQLQDHFSAVKLVGPEEALSAGEARDMAMDSCRQNPECEFYFSLDAD 397
Query: 1056 AYFSEPKVIKDLIQYSKTYDVGIIAPMIGQPGKLFTNFWGAIAANGYYARSEDYMAIVKG 877
A + P+ ++ LI+ ++ +IAPM+ + GKL++NFWGA++ N YYARSEDY+ +V+
Sbjct: 398 AVLTNPETLRVLIEQNRK----VIAPMLSRHGKLWSNFWGALSPNEYYARSEDYVELVQR 453
Query: 876 NRVGYWNVPFITSAVLFNKEKLEA---MKDAYSYNKNLDPDMSMCKFARDNGHFLYIDNE 706
RVG WNVP+I+ A + E L K+ +S + + DPDM+ CK RD G FL++ N+
Sbjct: 454 KRVGVWNVPYISQAYVIRGETLRTELPQKEVFS-SSDTDPDMAFCKSVRDKGIFLHLSNQ 512
Query: 705 KYYGFLIVSDEYAETVTEGKWHPEMWQIFENRELWEARYIHPGYHKIMEPEHVVDQACPD 526
+G L+ + Y HP++WQIF+N W +YIH Y + ++ E +V+Q CPD
Sbjct: 513 HEFGRLLATSRY----DTDHLHPDLWQIFDNPVDWREQYIHENYSRALDGEGLVEQPCPD 568
Query: 525 VYDFPLMSERFCEELIEEMEGFGRWSDGSNNDKRLAGGYENVPTRDIHMNQVGFERQWLY 346
VY FPL++E+ C+EL+EEME +G+WS G + D RLAGGYENVPT DIHM QVG+E QWL
Sbjct: 569 VYWFPLLTEQMCDELVEEMEHYGQWSGGRHEDSRLAGGYENVPTVDIHMKQVGYEDQWLQ 628
Query: 345 FMDTYVRPVQEKTFIGYYHQPVESNMMFVVRYKPEEQPSLRPHHDASTFSIDIALNKKGR 166
+ TYV P+ E F G YH + M FVVRY+P+EQPSLRPHHD+STF++++ALN KG
Sbjct: 629 LLRTYVGPMTEYLFPG-YHTKTRAVMNFVVRYRPDEQPSLRPHHDSSTFTLNVALNHKGV 687
Query: 165 DYEGGGVRYIRYNCTVPADEVGYAMMFPGRLTHLHEGLATTKGTRYIMVSFINP 4
DYEGGG R++RY+C + + G+A++ PGRLTH HEGL TT+GTRYIMVSF++P
Sbjct: 688 DYEGGGCRFLRYDCRISSPRKGWALLHPGRLTHYHEGLPTTRGTRYIMVSFVDP 741
>gi|30017429|ref|NP_835202.1| procollagen-lysine, 2-oxoglutarate
5-dioxygenase 3 [Rattus norvegicus]
gi|28400779|emb|CAD23628.1| procollagen-lysine, 2-oxoglutarate
5-dioxygenase 3 [Rattus norvegicus]
Length = 741
Score = 678 bits (1749), Expect = 0.0
Identities = 331/714 (46%), Positives = 476/714 (66%), Gaps = 7/714 (0%)
Frame = -1
Query: 2124 ELVVVTVATENTDGLKRLLESAKAFDINIEVLGLGEKWNGGDTRIEQGGGQKIRILSDWI 1945
+L+V+TVAT T+G +R L+SA+ F+ + LGLG++W GGD GGGQK+R L +
Sbjct: 41 KLLVITVATAETEGYRRFLQSAEFFNYTVRTLGLGQEWRGGDVARTVGGGQKVRWLKKEM 100
Query: 1944 EKYKDASDTMIMFVDAYDVVFNADSTTILRKFFEHYSEKRLLFGAEPFCWPDQSLAPEYP 1765
EKY D +IMFVD+YDV+ + T +L+KF + S LLF AE FCWPD LA +YP
Sbjct: 101 EKYASQEDMIIMFVDSYDVILASSPTELLKKFVQ--SGSHLLFSAESFCWPDWGLAEQYP 158
Query: 1764 IVEFGKRFLNSGLFMGYGPEMHKILKLKSVEDKDDDQLYYTMIYLDEKLRKELNMDLDSM 1585
V GKRFLNSG F+G+ P +H+I++ +D DDDQL+YT +YLD LR++L + LD
Sbjct: 159 EVGVGKRFLNSGGFIGFAPTIHRIVRQWKYKDDDDDQLFYTQLYLDPGLREKLKLSLDHK 218
Query: 1584 SKIFQNLNGVIEDVELQFKEDGTPEAYNAAYNTKPLIVHGNGPSKSHLNYLGNYLGNRWN 1405
S+IFQNLNG +++V L+F ++ N AY+T P++VHGNGP+K LNYLGNY+ N W
Sbjct: 219 SRIFQNLNGALDEVVLKFDQNRV-RIRNVAYDTLPVVVHGNGPTKLQLNYLGNYVPNGWT 277
Query: 1404 SQLGCRTCGLEVKE---SEEVPLIALNLFISKPIPFIEEVLQKIAEFDYPKEKIALYIYN 1234
Q GC C L + + P + L +F+ +P PF+ LQ++ DYP ++I+L+++N
Sbjct: 278 PQGGCGFCNLNRRTLPGGQPPPRVLLAVFVEQPTPFLPRFLQRLLLLDYPPDRISLFLHN 337
Query: 1233 NQPFSIKNIQDFLQKHGKSYYTKRVINGVTEIGDREARNEAIEWNKAR-NVEFAFLMDGD 1057
N+ + +I D + + +++ + EAR+ A++ + EF F +D D
Sbjct: 338 NEVYHEPHIADAWPQLQDHFSAVKLVGPEEALSSGEARDMAMDSCRQNPECEFYFSLDAD 397
Query: 1056 AYFSEPKVIKDLIQYSKTYDVGIIAPMIGQPGKLFTNFWGAIAANGYYARSEDYMAIVKG 877
A + P+ ++ LI+ ++ +IAPM+ + GKL++NFWGA++ + YYARSEDY+ +V+
Sbjct: 398 AVLTNPETLRILIEQNRK----VIAPMLSRHGKLWSNFWGALSPDEYYARSEDYVELVQR 453
Query: 876 NRVGYWNVPFITSAVLFNKEKLEAM---KDAYSYNKNLDPDMSMCKFARDNGHFLYIDNE 706
RVG WNVP+I+ A + E L K+ +S + + DPDM+ C+ RD G FL++ N+
Sbjct: 454 KRVGLWNVPYISQAYVIRGETLRTELPEKEVFS-SSDTDPDMAFCRSVRDKGIFLHLSNQ 512
Query: 705 KYYGFLIVSDEYAETVTEGKWHPEMWQIFENRELWEARYIHPGYHKIMEPEHVVDQACPD 526
+G L+ + Y HP++WQIF+N W +YIH Y + ++ E +V+Q CPD
Sbjct: 513 HEFGRLLSTSHY----DTDHLHPDLWQIFDNPVDWREQYIHENYSRALDGEGLVEQPCPD 568
Query: 525 VYDFPLMSERFCEELIEEMEGFGRWSDGSNNDKRLAGGYENVPTRDIHMNQVGFERQWLY 346
VY FPL++E+ C+EL+EEME +G+WS G + D RLAGGYENVPT DIHM QVG+E QWL
Sbjct: 569 VYWFPLLTEQMCDELVEEMEHYGQWSGGRHEDSRLAGGYENVPTVDIHMKQVGYEDQWLQ 628
Query: 345 FMDTYVRPVQEKTFIGYYHQPVESNMMFVVRYKPEEQPSLRPHHDASTFSIDIALNKKGR 166
+ TYV P+ E F G YH + M FVVRY+P+EQPSLRPHHD+STF++++ALN KG
Sbjct: 629 LLRTYVGPMTEHLFPG-YHTKTRAVMNFVVRYRPDEQPSLRPHHDSSTFTLNVALNHKGV 687
Query: 165 DYEGGGVRYIRYNCTVPADEVGYAMMFPGRLTHLHEGLATTKGTRYIMVSFINP 4
DYEGGG R++RY+C V + G+A++ PGRLTH HEGL TT+GTRYIMVSF++P
Sbjct: 688 DYEGGGCRFLRYDCRVSSPRKGWALLHPGRLTHYHEGLPTTRGTRYIMVSFVDP 741
>gi|4505891|ref|NP_001075.1| procollagen-lysine, 2-oxoglutarate
5-dioxygenase 3; procollagen-lysine, 2-oxoglutarate
5-dioxygenase 3v; lysyl hydroxylase 3 [Homo sapiens]
gi|6093731|sp|O60568|PLO3_HUMAN Procollagen-lysine,2-oxoglutarate
5-dioxygenase 3 precursor (Lysyl hydroxylase 3) (LH3)
gi|3153235|gb|AAC39753.1| lysyl hydroxylase isoform 3 [Homo sapiens]
gi|3551836|gb|AAC34808.1| lysyl hydroxylase 3 [Homo sapiens]
gi|5630086|gb|AAD45831.1| lysyl hydroxylase 3 [Homo sapiens]
gi|7546824|gb|AAF63701.1| lysyl hydroxylase 3 [Homo sapiens]
gi|15079714|gb|AAH11674.1| Procollagen-lysine, 2-oxoglutarate
5-dioxygenase 3 [Homo sapiens]
gi|28975434|gb|AAO61775.1| lysyl hydroxylase 3 [Homo sapiens]
Length = 738
Score = 668 bits (1724), Expect = 0.0
Identities = 331/714 (46%), Positives = 473/714 (65%), Gaps = 7/714 (0%)
Frame = -1
Query: 2124 ELVVVTVATENTDGLKRLLESAKAFDINIEVLGLGEKWNGGDTRIEQGGGQKIRILSDWI 1945
+L+V+TVAT T+G R L SA+ F+ + LGLGE+W GGD GGGQK+R L +
Sbjct: 38 KLLVITVATAETEGYLRFLRSAEFFNYTVRTLGLGEEWRGGDVARTVGGGQKVRWLKKEM 97
Query: 1944 EKYKDASDTMIMFVDAYDVVFNADSTTILRKFFEHYSEKRLLFGAEPFCWPDQSLAPEYP 1765
EKY D D +IMFVD+YDV+ T +L+KF + S RLLF AE FCWP+ LA +YP
Sbjct: 98 EKYADREDMIIMFVDSYDVILAGSPTELLKKFVQ--SGSRLLFSAESFCWPEWGLAEQYP 155
Query: 1764 IVEFGKRFLNSGLFMGYGPEMHKILKLKSVEDKDDDQLYYTMIYLDEKLRKELNMDLDSM 1585
V GKRFLNSG F+G+ +H+I++ +D DDDQL+YT +YLD LR++L+++LD
Sbjct: 156 EVGTGKRFLNSGGFIGFATTIHQIVRQWKYKDDDDDQLFYTRLYLDPGLREKLSLNLDHK 215
Query: 1584 SKIFQNLNGVIEDVELQFKEDGTPEAYNAAYNTKPLIVHGNGPSKSHLNYLGNYLGNRWN 1405
S+IFQNLNG +++V L+F + N AY+T P++VHGNGP+K LNYLGNY+ N W
Sbjct: 216 SRIFQNLNGALDEVVLKFDRNRV-RIRNVAYDTLPIVVHGNGPTKLQLNYLGNYVPNGWT 274
Query: 1404 SQLGCRTCGLEVKE---SEEVPLIALNLFISKPIPFIEEVLQKIAEFDYPKEKIALYIYN 1234
+ GC C + + + P + L +F+ +P PF+ LQ++ DYP +++ L+++N
Sbjct: 275 PEGGCGFCNQDRRTLPGGQPPPRVFLAVFVEQPTPFLPRFLQRLLLLDYPPDRVTLFLHN 334
Query: 1233 NQPFSIKNIQDFLQKHGKSYYTKRVINGVTEIGDREARNEAIEW-NKARNVEFAFLMDGD 1057
N+ F +I D + + +++ + EAR+ A++ + EF F +D D
Sbjct: 335 NEVFHEPHIADSWPQLQDHFSAVKLVGPEEALSPGEARDMAMDLCRQDPECEFYFSLDAD 394
Query: 1056 AYFSEPKVIKDLIQYSKTYDVGIIAPMIGQPGKLFTNFWGAIAANGYYARSEDYMAIVKG 877
A + + ++ LI+ ++ +IAPM+ + GKL++NFWGA++ + YYARSEDY+ +V+
Sbjct: 395 AVLTNLQTLRILIEENRK----VIAPMLSRHGKLWSNFWGALSPDEYYARSEDYVELVQR 450
Query: 876 NRVGYWNVPFITSAVLFNKEKLEA---MKDAYSYNKNLDPDMSMCKFARDNGHFLYIDNE 706
RVG WNVP+I+ A + + L +D +S + DPDM+ CK RD G FL++ N+
Sbjct: 451 KRVGVWNVPYISQAYVIRGDTLRMELPQRDVFS-GSDTDPDMAFCKSFRDKGIFLHLSNQ 509
Query: 705 KYYGFLIVSDEYAETVTEGKWHPEMWQIFENRELWEARYIHPGYHKIMEPEHVVDQACPD 526
+G L+ + Y TE HP++WQIF+N W+ +YIH Y + +E E +V+Q CPD
Sbjct: 510 HEFGRLLATSRYD---TE-HLHPDLWQIFDNPVDWKEQYIHENYSRALEGEGIVEQPCPD 565
Query: 525 VYDFPLMSERFCEELIEEMEGFGRWSDGSNNDKRLAGGYENVPTRDIHMNQVGFERQWLY 346
VY FPL+SE+ C+EL+ EME +G+WS G + D RLAGGYENVPT DIHM QVG+E QWL
Sbjct: 566 VYWFPLLSEQMCDELVAEMEHYGQWSGGRHEDSRLAGGYENVPTVDIHMKQVGYEDQWLQ 625
Query: 345 FMDTYVRPVQEKTFIGYYHQPVESNMMFVVRYKPEEQPSLRPHHDASTFSIDIALNKKGR 166
+ TYV P+ E F G YH + M FVVRY+P+EQPSLRPHHD+STF++++ALN KG
Sbjct: 626 LLRTYVGPMTESLFPG-YHTKARAVMNFVVRYRPDEQPSLRPHHDSSTFTLNVALNHKGL 684
Query: 165 DYEGGGVRYIRYNCTVPADEVGYAMMFPGRLTHLHEGLATTKGTRYIMVSFINP 4
DYEGGG R++RY+C + + G+A++ PGRLTH HEGL TT GTRYIMVSF++P
Sbjct: 685 DYEGGGCRFLRYDCVISSPRKGWALLHPGRLTHYHEGLPTTWGTRYIMVSFVDP 738
>gi|50759427|ref|XP_417641.1| PREDICTED: similar to procollagen-lysine
5-dioxygenase (EC 1.14.11.4) precursor - chicken [Gallus
gallus]
Length = 730
Score = 647 bits (1669), Expect = 0.0
Identities = 311/714 (43%), Positives = 471/714 (65%), Gaps = 8/714 (1%)
Frame = -1
Query: 2121 LVVVTVATENTDGLKRLLESAKAFDINIEVLGLGEKWNGGDTRIEQGGGQKIRILSDWIE 1942
L+V+TVAT+ T+G +R SA+ F+ I+VLGL E+W GGD + GGGQK+R+L ++
Sbjct: 30 LLVLTVATKQTEGFRRFRRSAQFFNYKIQVLGLDEEWKGGDDKKPAGGGQKVRLLKSALK 89
Query: 1941 KYKDASDTMIMFVDAYDVVFNADSTTILRKFFEHYSEKRLLFGAEPFCWPDQSLAPEYPI 1762
++ D D +I+F+++YDV+F + T +L+KF + ++ +++F AE + +PD+ L +YP
Sbjct: 90 QHADKEDLVILFIESYDVLFASGPTELLKKFKQ--AKSKVVFSAENYIYPDRKLEAKYPP 147
Query: 1761 VEFGKRFLNSGLFMGYGPEMHKILKLKSVEDKDDDQLYYTMIYLDEKLRKELNMDLDSMS 1582
V GKRFL SG F+GY P + K+++ +D D DQL+YT I+LD + R+ +N+ LD S
Sbjct: 148 VRDGKRFLGSGGFIGYAPNLKKLVEEWKGKDDDSDQLFYTKIFLDPEKRENINISLDHRS 207
Query: 1581 KIFQNLNGVIEDVELQFKEDGTPEAYNAAYNTKPLIVHGNGPSKSHLNYLGNYLGNRWNS 1402
+IFQNLNG +++V L+F E+ A N Y+T P+I+HGNGP+K LNYLGNY+ W
Sbjct: 208 RIFQNLNGALDEVVLKF-ENARVRARNLLYDTLPVIIHGNGPTKLQLNYLGNYIPQIWTF 266
Query: 1401 QLGCRTCGLEVK-----ESEEVPLIALNLFISKPIPFIEEVLQKIAEFDYPKEKIALYIY 1237
+ GC C ++ + E +P+I + +FI +P PF+ + ++ YPK++I ++I+
Sbjct: 267 ETGCTVCDEGLRSLTGIKDEALPMILIGIFIEQPTPFLSQFFLRLRNLHYPKQRIQIFIH 326
Query: 1236 NNQPFSIKNIQDFLQKHGKSYYTKRVINGVTEIGDREARNEAIEW-NKARNVEFAFLMDG 1060
N++ + F+++H K Y +VI E+ + EARN ++ K + ++ F +D
Sbjct: 327 NHEEHHSMQVDSFVKEHSKEYLAMKVIGPDDEVENAEARNLGMDLCRKDPDCDYYFSLDA 386
Query: 1059 DAYFSEPKVIKDLIQYSKTYDVGIIAPMIGQPGKLFTNFWGAIAANGYYARSEDYMAIVK 880
+ + ++ LI+ +K+ +IAP++ + KL++NFWGA++ +GYYARSEDY+ IV+
Sbjct: 387 EVVLKNTETLRILIEQNKS----VIAPLVSRHEKLWSNFWGALSPDGYYARSEDYVDIVQ 442
Query: 879 GNRVGYWNVPFITSAVLFNKE--KLEAMKDAYSYNKNLDPDMSMCKFARDNGHFLYIDNE 706
RVG WNVP+I+S + + +LE + + LD DM+ C R+ G F+Y+ N
Sbjct: 443 RRRVGLWNVPYISSVYMVKGKVLRLELDEGDLFHGGKLDADMAFCHNVRNQGVFMYLTNR 502
Query: 705 KYYGFLIVSDEYAETVTEGKWHPEMWQIFENRELWEARYIHPGYHKIMEPEHVVDQACPD 526
+G ++ + Y T H ++WQIF N E W +YIH Y ++ + +V+ CPD
Sbjct: 503 HQFGHILSLENYQTT----HLHNDLWQIFSNPEDWREKYIHENYTAALKGK-LVEMPCPD 557
Query: 525 VYDFPLMSERFCEELIEEMEGFGRWSDGSNNDKRLAGGYENVPTRDIHMNQVGFERQWLY 346
VY FP+ ++ C+EL+EEME +G+WS G N D R+ GGYENVPT DIHMNQ+GFER+W
Sbjct: 558 VYWFPIFTDTACDELVEEMEHYGKWSTGDNTDSRIQGGYENVPTIDIHMNQIGFEREWYK 617
Query: 345 FMDTYVRPVQEKTFIGYYHQPVESNMMFVVRYKPEEQPSLRPHHDASTFSIDIALNKKGR 166
F+ Y+ P+ EK + GYY + + + FVVRYKP+EQPSL PHHDASTF+I+IALN+ G
Sbjct: 618 FLLDYIAPITEKLYPGYYTK-TQFELAFVVRYKPDEQPSLMPHHDASTFTINIALNRVGI 676
Query: 165 DYEGGGVRYIRYNCTVPADEVGYAMMFPGRLTHLHEGLATTKGTRYIMVSFINP 4
DYEGGG R++RYNC++ A G+ +M PGRLTH HEGL TTKGTRYI VSFI+P
Sbjct: 677 DYEGGGCRFLRYNCSIRAPRKGWTLMHPGRLTHYHEGLPTTKGTRYIAVSFIDP 730
>gi|126651|sp|P24802|PLO1_CHICK Procollagen-lysine,2-oxoglutarate
5-dioxygenase 1 precursor (Lysyl hydroxylase 1) (LH1)
gi|86406|pir||A23742 procollagen-lysine 5-dioxygenase (EC 1.14.11.4)
precursor - chicken
gi|212282|gb|AAA48945.1| lysyl hydroxylase
Length = 730
Score = 647 bits (1668), Expect = 0.0
Identities = 311/714 (43%), Positives = 470/714 (65%), Gaps = 8/714 (1%)
Frame = -1
Query: 2121 LVVVTVATENTDGLKRLLESAKAFDINIEVLGLGEKWNGGDTRIEQGGGQKIRILSDWIE 1942
L+V+TVAT+ T+G +R SA+ F+ I+VLGL E+W GGD + GGGQK+R+L ++
Sbjct: 30 LLVLTVATKQTEGFRRFRRSAQFFNYKIQVLGLDEEWKGGDDKKPAGGGQKVRLLKSALK 89
Query: 1941 KYKDASDTMIMFVDAYDVVFNADSTTILRKFFEHYSEKRLLFGAEPFCWPDQSLAPEYPI 1762
++ D D +I+F+++YDV+F + T +L+KF + ++ +++F AE + +PD+ L +YP
Sbjct: 90 QHADKEDLVILFIESYDVLFASGPTELLKKFKQ--AKSKVVFSAENYIYPDRKLEAKYPP 147
Query: 1761 VEFGKRFLNSGLFMGYGPEMHKILKLKSVEDKDDDQLYYTMIYLDEKLRKELNMDLDSMS 1582
V GKRFL SG F+GY P + K+++ +D D DQL+YT I+LD + R+ +N+ LD S
Sbjct: 148 VRDGKRFLGSGGFIGYAPNLKKLVEEWKGKDDDSDQLFYTKIFLDPEKRENINISLDHRS 207
Query: 1581 KIFQNLNGVIEDVELQFKEDGTPEAYNAAYNTKPLIVHGNGPSKSHLNYLGNYLGNRWNS 1402
+IFQNLNG +++V L+F E+ A N Y+T P+I+HGNGP+K LNYLGNY+ W
Sbjct: 208 RIFQNLNGALDEVVLKF-ENARVRARNLLYDTLPVIIHGNGPTKLQLNYLGNYIPQIWTF 266
Query: 1401 QLGCRTCGLEVK-----ESEEVPLIALNLFISKPIPFIEEVLQKIAEFDYPKEKIALYIY 1237
+ GC C ++ + E +P+I + +FI +P PF+ + ++ YPK++I ++I+
Sbjct: 267 ETGCTVCDEGLRSLTGIKDEALPMILIGIFIEQPTPFLSQFFLRLRNLHYPKQRIQIFIH 326
Query: 1236 NNQPFSIKNIQDFLQKHGKSYYTKRVINGVTEIGDREARNEAIEW-NKARNVEFAFLMDG 1060
N++ + F+++H K Y +VI E+ + EARN ++ K + ++ F +D
Sbjct: 327 NHEEHHSMQVDSFVKEHSKEYLAMKVIGPDDEVENAEARNLGMDLCRKDPDCDYYFSLDA 386
Query: 1059 DAYFSEPKVIKDLIQYSKTYDVGIIAPMIGQPGKLFTNFWGAIAANGYYARSEDYMAIVK 880
+ + ++ LI+ +K+ +IAP++ + KL++NFWGA++ +GYYARSEDY+ IV+
Sbjct: 387 EVVLKNTETLRILIEQNKS----VIAPLVSRHEKLWSNFWGALSPDGYYARSEDYVDIVQ 442
Query: 879 GNRVGYWNVPFITSAVLFNKEKLEAMKDAYS--YNKNLDPDMSMCKFARDNGHFLYIDNE 706
RVG WNVP+I+S + + L + D + LD DM+ C R+ G F+Y+ N
Sbjct: 443 RRRVGLWNVPYISSVYMVKGKVLRSELDEGDLFHGGKLDADMAFCHNVRNQGVFMYLTNR 502
Query: 705 KYYGFLIVSDEYAETVTEGKWHPEMWQIFENRELWEARYIHPGYHKIMEPEHVVDQACPD 526
+G ++ + Y T H ++WQIF N E W +YIH Y ++ + +V+ CPD
Sbjct: 503 HQFGHILSLENYQTT----HLHNDLWQIFSNPEDWREKYIHENYTAALKGK-LVEMPCPD 557
Query: 525 VYDFPLMSERFCEELIEEMEGFGRWSDGSNNDKRLAGGYENVPTRDIHMNQVGFERQWLY 346
VY FP+ ++ C+EL+EEME +G+WS G N D R+ GGYENVPT DIHMNQ+GFER+W
Sbjct: 558 VYWFPIFTDTACDELVEEMEHYGKWSTGDNTDSRIQGGYENVPTIDIHMNQIGFEREWYK 617
Query: 345 FMDTYVRPVQEKTFIGYYHQPVESNMMFVVRYKPEEQPSLRPHHDASTFSIDIALNKKGR 166
F+ Y+ P+ EK + GYY + + + FVVRYKP+EQPSL PHHDASTF+I+IALN+ G
Sbjct: 618 FLLDYIAPITEKLYPGYYTK-TQFELAFVVRYKPDEQPSLMPHHDASTFTINIALNRVGI 676
Query: 165 DYEGGGVRYIRYNCTVPADEVGYAMMFPGRLTHLHEGLATTKGTRYIMVSFINP 4
DYEGGG R++RYNC++ A G+ +M PGRLTH HEGL TTKGTRYI VSFI+P
Sbjct: 677 DYEGGGCRFLRYNCSIRAPRKGWTLMHPGRLTHYHEGLPTTKGTRYIAVSFIDP 730
>gi|31242367|ref|XP_321614.1| ENSANGP00000011729 [Anopheles gambiae]
gi|21288577|gb|EAA00870.1| ENSANGP00000011729 [Anopheles gambiae str.
PEST]
Length = 783
Score = 647 bits (1668), Expect = 0.0
Identities = 334/713 (46%), Positives = 466/713 (64%), Gaps = 6/713 (0%)
Frame = -1
Query: 2124 ELVVVTVATENTDGLKRLLESAKAFDINIEVLGLGEKWNGGDTRIEQGGGQKIRILSDWI 1945
E ++ TVA+ T+G R L SAK +D+ + LG+G+ W GG+ + GGG KI +L + +
Sbjct: 89 EPLIFTVASNATEGYVRYLRSAKHYDLTVTTLGMGKPWLGGNMK-SVGGGYKINLLREAL 147
Query: 1944 EKYKDASDTMIMFVDAYDVVFNADSTTILRKFFEHYSEKRLLFGAEPFCWPDQSLAPEYP 1765
+ Y+ D +++F D+YDV+F A I KF E +LFGAE FCWPD+SL YP
Sbjct: 148 KPYRADKDRLVLFTDSYDVLFLAPWAKIQEKFASF--EASILFGAEGFCWPDESLKSAYP 205
Query: 1764 IVEF-GKRFLNSGLFMGYGPEMHKILKLKSVEDKDDDQLYYTMIYLDEKLRKELNMDLDS 1588
+E G R+LNSGLFMGY +++K+LK V+D +DDQLYYT YLDE+LR+ELN+ LD
Sbjct: 206 PLEGRGMRYLNSGLFMGYADKLYKLLKTP-VKDAEDDQLYYTKAYLDEELRQELNIKLDH 264
Query: 1587 MSKIFQNLNGVIEDVELQFKEDGTPEAY--NAAYNTKPLIVHGNGPSKSHLNYLGNYLGN 1414
M+ +FQNLNGV E V L E EA N+ YNTKP IVHGNGPSK LN NYL
Sbjct: 265 MATLFQNLNGVEEQVVLSL-EPSEKEATLANSEYNTKPAIVHGNGPSKLTLNSYANYLAG 323
Query: 1413 RWNSQLGCRTC--GLEVKESEEVPLIALNLFISKPIPFIEEVLQKIAEFDYPKEKIALYI 1240
+ C+T G E+PL+ + LF+ KP PF+EE IA+ +YP +++ + +
Sbjct: 324 AFVDG-ECQTVKEGRLTLSGGELPLVTMALFVEKPTPFLEEWFGTIAKLNYPADRLDVLV 382
Query: 1239 YNNQPFSIKNIQDFLQKHGKSYYTKRVINGVTEIGDREARNEAIEWNKARNVEFAFLMDG 1060
++N + ++ FL Y + +VI + + ARN A + + R ++ F++D
Sbjct: 383 HSNVAYHAGTVKAFLDAQEGRYRSLKVIEHDGDFTETAARNFATKHCELRGCDYLFVVDS 442
Query: 1059 DAYFSEPKVIKDLIQYSKTYDVGIIAPMIGQPGKLFTNFWGAIAANGYYARSEDYMAIVK 880
+ + +P V++ LI+ ++ +IAP++ +P K+++NFWGA++ G+YARS DYM IV
Sbjct: 443 EGHLDDPNVLRALIEANRN----VIAPVLTRPEKVWSNFWGALSGQGFYARSNDYMDIVG 498
Query: 879 GNRVGYWNVPFITSAVLFNKEKLEAMKDAYSYN-KNLDPDMSMCKFARDNGHFLYIDNEK 703
+G WNVPF++ L + L + SY + DPDM++C R G F+++ N +
Sbjct: 499 RKLLGLWNVPFVSIVYLVKRAVLPEV----SYELQETDPDMALCWHFRSKGIFMHVINVE 554
Query: 702 YYGFLIVSDEYAETVTEGKWHPEMWQIFENRELWEARYIHPGYHKIMEPEHVVDQACPDV 523
YG LI ++ + T T HP+ +Q+F NR WE RY+ PGY + +E + V Q CPDV
Sbjct: 555 QYGHLIDTEYFDMTRT----HPDFYQLFNNRHDWEQRYLAPGYKQQLEADFVPQQPCPDV 610
Query: 522 YDFPLMSERFCEELIEEMEGFGRWSDGSNNDKRLAGGYENVPTRDIHMNQVGFERQWLYF 343
Y F + S+RFC++L E +E FG WSDGS++DKRL GGYE VPTRDIHMNQVG E+ WL F
Sbjct: 611 YWFAIGSDRFCDDLREIVEAFGEWSDGSHSDKRLQGGYEAVPTRDIHMNQVGLEQLWLKF 670
Query: 342 MDTYVRPVQEKTFIGYYHQPVESNMMFVVRYKPEEQPSLRPHHDASTFSIDIALNKKGRD 163
+ YVRP+QEK FIGY+H P S M FVVRY+P+EQPSLRPHHD+ST++I+IALN G D
Sbjct: 671 LQLYVRPLQEKVFIGYFHDPPRSLMNFVVRYRPDEQPSLRPHHDSSTYTINIALNTAGVD 730
Query: 162 YEGGGVRYIRYNCTVPADEVGYAMMFPGRLTHLHEGLATTKGTRYIMVSFINP 4
YEGGG R++RYNC+V G+ ++ PGRLTH HEGL TTKGTRYIM+SF++P
Sbjct: 731 YEGGGCRFLRYNCSVTDTRKGWMLLHPGRLTHFHEGLLTTKGTRYIMISFVDP 783
>gi|50752229|ref|XP_422695.1| PREDICTED: similar to
procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine
hydroxylase) 2 isoform a; Procollagen-lysine,
2-oxoglutarate 5-dioxygenase (lysine hydroxylase) [Gallus
gallus]
Length = 1100
Score = 644 bits (1662), Expect = 0.0
Identities = 317/733 (43%), Positives = 472/733 (64%), Gaps = 27/733 (3%)
Frame = -1
Query: 2121 LVVVTVATENTDGLKRLLESAKAFDINIEVLGLGEKWNGGDTRIEQGGGQKIRILSDWIE 1942
L+V TVAT+ TDG R +++AK F+ ++VLG GE+W GG+ GGGQK+R+L + I+
Sbjct: 381 LLVFTVATKETDGFHRFMQTAKHFNYTVKVLGKGEEWKGGELANSIGGGQKVRLLKEGIQ 440
Query: 1941 KYKDASDTMIMFVDAYDVVFNADSTTILRKFFEHYSEKRLLFGAEPFCWPDQSLAPEYPI 1762
Y D D ++MFV+ YDV+F +L+KF E + +++F A+ WPD+ LA +YP+
Sbjct: 441 SYADQEDLIVMFVECYDVIFAGGPEELLKKFQE--TNHKVVFAADGLIWPDKRLADKYPV 498
Query: 1761 VEFGKRFLNSGLFMGYGPEMHKILKLKSVEDKDDDQLYYTMIYLDEKLRKELNMDLDSMS 1582
V GKRFLNSG F+GY P +++I++ +++D DDDQL+YT IY+D R+ LN+ LD
Sbjct: 499 VRSGKRFLNSGGFIGYAPYINRIVQQWNLQDNDDDQLFYTKIYVDPLARERLNITLDHKC 558
Query: 1581 KIFQNLNGVIEDVELQFKEDGTPEAYNAAYNTKPLIVHGNGPSKSHLNYLGNYLGNRWNS 1402
IFQ LNG +++V L F E+G A N+ Y T P+ V GNGP+K +LNYLGNY+ N W
Sbjct: 559 AIFQTLNGAVDEVHLNF-EEGKVRARNSVYETLPITVLGNGPTKIYLNYLGNYIPNAWTR 617
Query: 1401 QLGCRTCGLEVKESE---EVPLIALNLFISKPIPFIEEVLQKIAEFDYPKEKIALYIYNN 1231
+ GC C L++ + E P + + +FI +P PF+ + L ++ DYPKE ++++I+NN
Sbjct: 618 ETGCNICDLDMLDLSTVTEYPRVKIGVFIEQPTPFLPKFLDRLLTLDYPKEALSVFIHNN 677
Query: 1230 QPFSIKNIQDFLQKHGKSYYTKRVINGVTEIGDREARNEAIEWNKARNV-EFAFLMDGDA 1054
+ + K+I+ F +K +++ + EARN ++ + E+ F +D D
Sbjct: 678 EVYHEKHIKKFWEKAKNIIRNIKIVGPEENLSQAEARNMGMDLCRQDEACEYYFSIDADV 737
Query: 1053 YFSEPKVIKDLIQYSKTYDVGIIAPMIGQPGKLFTNFWGAIAANGYYARSEDYMAIVKGN 874
+ PK +K LI+ ++ IIAP++ + GKL++NFWGA++ +GYYARSEDY+ IV+GN
Sbjct: 738 VLTNPKTLKILIEQNRK----IIAPLVTRHGKLWSNFWGALSPDGYYARSEDYIDIVQGN 793
Query: 873 RVGYWNVPFITSAVLFNKEKLEA-MKDA-YSYNKNLDPDMSMCKFARD------------ 736
RVG WN+P++ + L + L + MK+ Y LDPDM++C+ AR+
Sbjct: 794 RVGVWNIPYMANIYLIKGQTLRSEMKEKNYFMRDKLDPDMALCRNAREMTLQREKDSPSS 853
Query: 735 ---------NGHFLYIDNEKYYGFLIVSDEYAETVTEGKWHPEMWQIFENRELWEARYIH 583
G F+YI N +G LI + Y ++ ++WQIFEN W+ YI+
Sbjct: 854 ETFHMLRPPKGVFMYITNRHEFGRLISTANY----NTSHYNNDLWQIFENPVDWKETYIN 909
Query: 582 PGYHKIMEPEHVVDQACPDVYDFPLMSERFCEELIEEMEGFGRWSDGSNNDKRLAGGYEN 403
P Y KI +++V+Q CPDV+ FP+ S+ C+EL+EEME FG+WS G + D R++GGYEN
Sbjct: 910 PNYSKIFT-DNIVEQPCPDVFWFPIFSDTACDELVEEMEHFGQWSGGKHQDSRISGGYEN 968
Query: 402 VPTRDIHMNQVGFERQWLYFMDTYVRPVQEKTFIGYYHQPVESNMMFVVRYKPEEQPSLR 223
VPT DIHM Q+G + +WL+F+ ++ PV K F GYY + + + FVV+Y P+ Q SLR
Sbjct: 969 VPTDDIHMKQIGLDNEWLHFIREFIAPVTLKVFAGYYTKGY-ALLNFVVKYSPDRQRSLR 1027
Query: 222 PHHDASTFSIDIALNKKGRDYEGGGVRYIRYNCTVPADEVGYAMMFPGRLTHLHEGLATT 43
PHHD+STF+I+IALNK G D++GGG +++RYNC++ + G++ M PGRLTHLHEGL
Sbjct: 1028 PHHDSSTFTINIALNKVGEDFQGGGCKFLRYNCSIESPRKGWSFMHPGRLTHLHEGLPIL 1087
Query: 42 KGTRYIMVSFINP 4
GTRYI VSFI+P
Sbjct: 1088 NGTRYIAVSFIDP 1100
>gi|16741721|gb|AAH16657.1| Lysyl hydroxylase, precursor [Homo
sapiens]
Length = 727
Score = 638 bits (1645), Expect = 0.0
Identities = 313/714 (43%), Positives = 465/714 (64%), Gaps = 8/714 (1%)
Frame = -1
Query: 2121 LVVVTVATENTDGLKRLLESAKAFDINIEVLGLGEKWNGGDTRIEQGGGQKIRILSDWIE 1942
L+V+TVAT+ T+G +R SA+ F+ I+ LGLGE WN + GGGQK+R+L +E
Sbjct: 28 LLVLTVATKETEGFRRFKRSAQFFNYKIQALGLGEDWNV-EKGTSAGGGQKVRLLKKALE 86
Query: 1941 KYKDASDTMIMFVDAYDVVFNADSTTILRKFFEHYSEKRLLFGAEPFCWPDQSLAPEYPI 1762
K+ D D +I+F D+YDV+F + +L+KF + S +++F AE +PD+ L +YP+
Sbjct: 87 KHADKEDLVILFTDSYDVLFASGPRELLKKFRQ--SRSQVVFSAEELIYPDRRLETKYPV 144
Query: 1761 VEFGKRFLNSGLFMGYGPEMHKILKLKSVEDKDDDQLYYTMIYLDEKLRKELNMDLDSMS 1582
V GKRFL SG F+GY P + K++ +D D DQL+YT I+LD + R+++N+ LD
Sbjct: 145 VSDGKRFLGSGGFIGYAPNLSKLVAEWEGQDSDSDQLFYTKIFLDPEKREQINITLDHRC 204
Query: 1581 KIFQNLNGVIEDVELQFKEDGTPEAYNAAYNTKPLIVHGNGPSKSHLNYLGNYLGNRWNS 1402
+IFQNL+G +++V L+F E G A N AY+T P+++HGNGP+K LNYLGNY+ W
Sbjct: 205 RIFQNLDGALDEVVLKF-EMGHVRARNLAYDTLPVLIHGNGPTKLQLNYLGNYIPRFWTF 263
Query: 1401 QLGCRTCGLEVKE-----SEEVPLIALNLFISKPIPFIEEVLQKIAEFDYPKEKIALYIY 1237
+ GC C ++ E +P + + +FI +P PF+ Q++ YP++ + L+I+
Sbjct: 264 ETGCTVCDEGLRSLKGIGDEALPTVLVGVFIEQPTPFVSLFFQRLLRLHYPQKHMRLFIH 323
Query: 1236 NNQPFSIKNIQDFLQKHGKSYYTKRVINGVTEIGDREARNEAIEW-NKARNVEFAFLMDG 1060
N++ +++FL +HG Y + +++ + + +ARN + + R+ + F +D
Sbjct: 324 NHEQHHKAQVEEFLAQHGSEYQSVKLVGPEVRMANADARNMGADLCRQDRSCTYYFSVDA 383
Query: 1059 DAYFSEPKVIKDLIQYSKTYDVGIIAPMIGQPGKLFTNFWGAIAANGYYARSEDYMAIVK 880
D +EP ++ LIQ +K +IAP++ + G+L++NFWGA++A+GYYARSEDY+ IV+
Sbjct: 384 DVALTEPNSLRLLIQQNKN----VIAPLMTRHGRLWSNFWGALSADGYYARSEDYVDIVQ 439
Query: 879 GNRVGYWNVPFITSAVLFNKEKL--EAMKDAYSYNKNLDPDMSMCKFARDNGHFLYIDNE 706
G RVG WNVP+I++ L L E ++ LDPDM+ C R F+++ N
Sbjct: 440 GRRVGVWNVPYISNIYLIKGSALRGELQSSDLFHHSKLDPDMAFCANIRQQDVFMFLTNR 499
Query: 705 KYYGFLIVSDEYAETVTEGKWHPEMWQIFENRELWEARYIHPGYHKIMEPEHVVDQACPD 526
G L+ D Y T H ++W++F N E W+ +YIH Y K + + +V+ CPD
Sbjct: 500 HTLGHLLSLDSYRTT----HLHNDLWEVFSNPEDWKEKYIHQNYTKALAGK-LVETPCPD 554
Query: 525 VYDFPLMSERFCEELIEEMEGFGRWSDGSNNDKRLAGGYENVPTRDIHMNQVGFERQWLY 346
VY FP+ +E C+EL+EEME FG+WS G+N D R+ GGYENVPT DIHMNQ+GFER+W
Sbjct: 555 VYWFPIFTEVACDELVEEMEHFGQWSLGNNKDNRIQGGYENVPTIDIHMNQIGFEREWHK 614
Query: 345 FMDTYVRPVQEKTFIGYYHQPVESNMMFVVRYKPEEQPSLRPHHDASTFSIDIALNKKGR 166
F+ Y+ P+ EK + GYY + + ++ FVVRYKP+EQPSL PHHDASTF+I+IALN+ G
Sbjct: 615 FLLEYIAPMTEKLYPGYYTR-AQFDLAFVVRYKPDEQPSLMPHHDASTFTINIALNRVGV 673
Query: 165 DYEGGGVRYIRYNCTVPADEVGYAMMFPGRLTHLHEGLATTKGTRYIMVSFINP 4
DYEGGG R++RYNC++ A G+ +M PGRLTH HEGL TT+GTRYI VSF++P
Sbjct: 674 DYEGGGCRFLRYNCSIRAPRKGWTLMHPGRLTHYHEGLPTTRGTRYIAVSFVDP 727
>gi|4505889|ref|NP_000926.1| procollagen-lysine, 2-oxoglutarate
5-dioxygenase (lysine hydroxylase) 2 isoform b;
Procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine
hydroxylase) [Homo sapiens]
gi|6093730|sp|O00469|PLO2_HUMAN Procollagen-lysine,2-oxoglutarate
5-dioxygenase 2 precursor (Lysyl hydroxylase 2) (LH2)
gi|7433178|pir||A59144 procollagen-lysine 5-dioxygenase (EC
1.14.11.4) 2 precursor - human
gi|2138314|gb|AAB58363.1| lysyl hydroxylase isoform 2 [Homo sapiens]
Length = 737
Score = 637 bits (1643), Expect = 0.0
Identities = 308/713 (43%), Positives = 465/713 (65%), Gaps = 6/713 (0%)
Frame = -1
Query: 2124 ELVVVTVATENTDGLKRLLESAKAFDINIEVLGLGEKWNGGDTRIEQGGGQKIRILSDWI 1945
+L+V+TVAT+ +DG R ++SAK F+ ++VLG GE+W GGD GGGQK+R++ + +
Sbjct: 38 KLLVITVATKESDGFHRFMQSAKYFNYTVKVLGQGEEWRGGDGINSIGGGQKVRLMKEVM 97
Query: 1944 EKYKDASDTMIMFVDAYDVVFNADSTTILRKFFEHYSEKRLLFGAEPFCWPDQSLAPEYP 1765
E Y D D ++MF + +DV+F +L+KF + + +++F A+ WPD+ LA +YP
Sbjct: 98 EHYADQDDLVVMFTECFDVIFAGGPEEVLKKFQK--ANHKVVFAADGILWPDKRLADKYP 155
Query: 1764 IVEFGKRFLNSGLFMGYGPEMHKILKLKSVEDKDDDQLYYTMIYLDEKLRKELNMDLDSM 1585
+V GKR+LNSG F+GY P +++I++ +++D DDDQL+YT +Y+D R+ +N+ LD
Sbjct: 156 VVHIGKRYLNSGGFIGYAPYVNRIVQQWNLQDNDDDQLFYTKVYIDPLKREAINITLDHK 215
Query: 1584 SKIFQNLNGVIEDVELQFKEDGTPEAYNAAYNTKPLIVHGNGPSKSHLNYLGNYLGNRWN 1405
KIFQ LNG +++V L+F E+G A N Y T P+ ++GNGP+K LNY GNY+ N W
Sbjct: 216 CKIFQTLNGAVDEVVLKF-ENGKARAKNTFYETLPVAINGNGPTKILLNYFGNYVPNSWT 274
Query: 1404 SQLGCRTCGLEVKESEEV---PLIALNLFISKPIPFIEEVLQKIAEFDYPKEKIALYIYN 1234
GC C + + V P +++ +FI +P PF+ L + DYPKE + L+I+N
Sbjct: 275 QDNGCTLCEFDTVDLSAVDVHPNVSIGVFIEQPTPFLPRFLDILLTLDYPKEALKLFIHN 334
Query: 1233 NQPFSIKNIQDFLQKHGKSYYTKRVINGVTEIGDREARNEAIEW-NKARNVEFAFLMDGD 1057
+ + K+I+ F K T +++ + EARN +++ + ++ F +D D
Sbjct: 335 KEVYHEKDIKVFFDKAKHEIKTIKIVGPEENLSQAEARNMGMDFCRQDEKCDYYFSVDAD 394
Query: 1056 AYFSEPKVIKDLIQYSKTYDVGIIAPMIGQPGKLFTNFWGAIAANGYYARSEDYMAIVKG 877
+ P+ +K LI+ ++ IIAP++ + GKL++NFWGA++ +GYYARSEDY+ IV+G
Sbjct: 395 VVLTNPRTLKILIEQNRK----IIAPLVTRHGKLWSNFWGALSPDGYYARSEDYVDIVQG 450
Query: 876 NRVGYWNVPFITSAVLFNKEKLEAMKDAYSY--NKNLDPDMSMCKFARDNGHFLYIDNEK 703
NRVG WNVP++ + L + L + + +Y LDPDM++C+ AR+ G F+YI N
Sbjct: 451 NRVGVWNVPYMANVYLIKGKTLRSEMNERNYFVRDKLDPDMALCRNAREMGVFMYISNRH 510
Query: 702 YYGFLIVSDEYAETVTEGKWHPEMWQIFENRELWEARYIHPGYHKIMEPEHVVDQACPDV 523
+G L+ + Y ++ ++WQIFEN W+ +YI+ Y KI E++V+Q CPDV
Sbjct: 511 EFGRLLSTANY----NTSHYNNDLWQIFENPVDWKEKYINRDYSKIFT-ENIVEQPCPDV 565
Query: 522 YDFPLMSERFCEELIEEMEGFGRWSDGSNNDKRLAGGYENVPTRDIHMNQVGFERQWLYF 343
+ FP+ SE+ C+EL+EEME +G+WS G ++D R++GGYENVPT DIHM QV E WL F
Sbjct: 566 FWFPIFSEKACDELVEEMEHYGKWSGGKHHDSRISGGYENVPTDDIHMKQVDLENVWLDF 625
Query: 342 MDTYVRPVQEKTFIGYYHQPVESNMMFVVRYKPEEQPSLRPHHDASTFSIDIALNKKGRD 163
+ ++ PV K F GYY + + + FVV+Y PE Q SLRPHHDASTF+I+IALN G D
Sbjct: 626 IREFIAPVTLKVFAGYYTKGF-ALLNFVVKYSPERQRSLRPHHDASTFTINIALNNVGED 684
Query: 162 YEGGGVRYIRYNCTVPADEVGYAMMFPGRLTHLHEGLATTKGTRYIMVSFINP 4
++GGG +++RYNC++ + G++ M PGRLTHLHEGL GTRYI VSFI+P
Sbjct: 685 FQGGGCKFLRYNCSIESPRKGWSFMHPGRLTHLHEGLPVKNGTRYIAVSFIDP 737
>gi|16758678|ref|NP_446279.1| procollagen-lysine, 2-oxoglutarate
5-dioxygenase (lysine hydroxylase, Ehlers-Danlos syndrome
type VI) [Rattus norvegicus]
gi|6093729|sp|Q63321|PLO1_RAT Procollagen-lysine,2-oxoglutarate
5-dioxygenase 1 precursor (Lysyl hydroxylase 1) (LH1)
gi|2143937|pir||S59964 procollagen-lysine 5-dioxygenase (EC
1.14.11.4) precursor - rat
gi|409059|gb|AAA41550.1| lysyl hydroxylase
gi|1584463|prf||2123247A Lys hydroxylase
Length = 728
Score = 637 bits (1642), Expect = 0.0
Identities = 314/715 (43%), Positives = 466/715 (64%), Gaps = 9/715 (1%)
Frame = -1
Query: 2121 LVVVTVATENTDGLKRLLESAKAFDINIEVLGLGEKWNGGDTRIEQGGGQKIRILSDWIE 1942
L+V+TVAT+ T+G +R SA+ F+ I+ LGLGE W+ GGGQK+R+L ++
Sbjct: 28 LLVLTVATKETEGFRRFKRSAQFFNYKIQSLGLGEDWSAAGGPSAAGGGQKVRLLKKALK 87
Query: 1941 KYKDASDTMIMFVDAYDVVFNADSTTILRKFFEHYSEKRLLFGAEPFCWPDQSLAPEYPI 1762
KY D D +I+FVD+YDVVF + +L+KF + ++ R++F AE +PD+ L +YP
Sbjct: 88 KYADKEDLVILFVDSYDVVFASGPRELLKKFQQ--AKSRVVFSAEELIYPDRRLEAKYPT 145
Query: 1761 VEFGKRFLNSGLFMGYGPEMHKILKLKSVEDKDDDQLYYTMIYLDEKLRKELNMDLDSMS 1582
V GKRFL SG F+GY P + K++ +D D DQL+YT I+LD + R+++N+ LD
Sbjct: 146 VPDGKRFLGSGGFIGYAPSLSKLVAEWEGQDNDSDQLFYTKIFLDPEKREQINISLDHRC 205
Query: 1581 KIFQNLNGVIEDVELQFKEDGTPEAYNAAYNTKPLIVHGNGPSKSHLNYLGNYLGNRWNS 1402
+IFQNL+G +++V L+F E G A N AY+T P+++HGNGP+K +NYLGNY+ W
Sbjct: 206 RIFQNLDGALDEVVLKF-EMGHVRARNLAYDTLPVVIHGNGPTKLQVNYLGNYIPRFWTF 264
Query: 1401 QLGCRTCGLEVKE-----SEEVPLIALNLFISKPIPFIEEVLQKIAEFDYPKEKIALYIY 1237
+ GC C ++ E +P + + +FI +P PF+ +++ YP++++ L+I+
Sbjct: 265 ETGCTVCDEGLRSLKGIGDEALPTVLVGVFIEQPTPFLSLFFRRLLHLRYPQKQMRLFIH 324
Query: 1236 NNQPFSIKNIQDFLQKHGKSYYTKRVINGVTEIGDREARNEAIEW-NKARNVEFAFLMDG 1060
N + ++ FL +HG Y + +++ + + +ARN + + + + F +D
Sbjct: 325 NQEQHHKLQVEQFLAEHGGEYQSVKLVGPEVRMANADARNMGADLCRQDQTCTYYFSVDA 384
Query: 1059 DAYFSEPKVIKDLIQYSKTYDVGIIAPMIGQPGKLFTNFWGAIAANGYYARSEDYMAIVK 880
D +EP ++ LI+ +K +IAP++ + G+L++NFWGA++A+GYYARSEDY+ IV+
Sbjct: 385 DVALTEPNSLRLLIEQNKN----VIAPLMTRHGRLWSNFWGALSADGYYARSEDYVDIVQ 440
Query: 879 GNRVGYWNVPFITSAVLFNKEKLEAMK---DAYSYNKNLDPDMSMCKFARDNGHFLYIDN 709
G RVG WNVP+I++ L L A D + Y+K LDPDMS C R F+++ N
Sbjct: 441 GRRVGVWNVPYISNIYLIKGSALRAELRHVDLFHYSK-LDPDMSFCANVRQQEVFMFLTN 499
Query: 708 EKYYGFLIVSDEYAETVTEGKWHPEMWQIFENRELWEARYIHPGYHKIMEPEHVVDQACP 529
+G L+ D Y T H ++W++F N + W+ +YIH Y K + + +V+ CP
Sbjct: 500 RHTFGHLLSLDNYQTT----HLHNDLWEVFSNPQDWKEKYIHENYTKALAGK-LVETPCP 554
Query: 528 DVYDFPLMSERFCEELIEEMEGFGRWSDGSNNDKRLAGGYENVPTRDIHMNQVGFERQWL 349
DVY FP+ +E C+EL+EEME +G+WS G N D R+ GGYENVPT DIHMNQ+ FER+W
Sbjct: 555 DVYWFPIFTEVACDELVEEMEHYGQWSLGDNKDNRIQGGYENVPTIDIHMNQITFEREWH 614
Query: 348 YFMDTYVRPVQEKTFIGYYHQPVESNMMFVVRYKPEEQPSLRPHHDASTFSIDIALNKKG 169
F+ Y+ P+ EK + GYY + + ++ FVVRYKP+EQPSL PHHDASTF+I+IALN+ G
Sbjct: 615 KFLVEYIAPLTEKLYPGYYTK-AQFDLAFVVRYKPDEQPSLMPHHDASTFTINIALNRVG 673
Query: 168 RDYEGGGVRYIRYNCTVPADEVGYAMMFPGRLTHLHEGLATTKGTRYIMVSFINP 4
DYEGGG R++RYNC+V A G+A+M PGRLTH HEGL TTKGTRYI VSF++P
Sbjct: 674 EDYEGGGCRFLRYNCSVRAPRKGWALMHPGRLTHYHEGLPTTKGTRYIAVSFVDP 728
>gi|24662591|ref|NP_648451.1| CG6199-PA [Drosophila melanogaster]
gi|24662595|ref|NP_729687.1| CG6199-PB [Drosophila melanogaster]
gi|7294743|gb|AAF50079.1| CG6199-PA [Drosophila melanogaster]
gi|23093644|gb|AAN11883.1| CG6199-PB [Drosophila melanogaster]
Length = 721
Score = 637 bits (1642), Expect = 0.0
Identities = 321/714 (44%), Positives = 464/714 (64%), Gaps = 7/714 (0%)
Frame = -1
Query: 2124 ELVVVTVATENTDGLKRLLESAKAFDINIEVLGLGEKWNGGDTRIEQGGGQKIRILSDWI 1945
++ V TVATE TDG R + SA+ +DI + LGLGE+W GGD + + GGG K+ +L + I
Sbjct: 28 KIKVFTVATEPTDGYTRYIRSARVYDIEVTTLGLGEEWKGGDMQ-KPGGGFKLNLLREAI 86
Query: 1944 EKYKDASDTMIMFVDAYDVVFNADSTTILRKFFEHYSEK--RLLFGAEPFCWPDQSLAPE 1771
YK+ +T+I+F D+YDV+ TT L + FE + E ++LF AE +CWPD+SLA +
Sbjct: 87 APYKNEPETIILFTDSYDVII----TTTLDEIFEKFKESGAKILFSAEKYCWPDKSLAND 142
Query: 1770 YPIVEFGK--RFLNSGLFMGYGPEMHKILKLKSVEDKDDDQLYYTMIYLDEKLRKELNMD 1597
YP VE GK RFLNSG F+GY P++ +L + +ED DDQLY+T I+LDE R +L +
Sbjct: 143 YPEVE-GKASRFLNSGAFIGYAPQVFALL-VDPIEDTADDQLYFTKIFLDETKRAKLGLK 200
Query: 1596 LDSMSKIFQNLNGVIEDVELQFK-EDGTPEAYNAAYNTKPLIVHGNGPSKSHLNYLGNYL 1420
LD S++FQNL+G DV+L+ E N + T P I+HGNG SK LN GNYL
Sbjct: 201 LDVQSRLFQNLHGAKNDVKLKVDLESNQGVLQNVDFMTTPSIIHGNGLSKVDLNAYGNYL 260
Query: 1419 GNRWNSQLGCRTCGLEVKESEE--VPLIALNLFISKPIPFIEEVLQKIAEFDYPKEKIAL 1246
+N C C + + EE +P+I+L L +++P+PF ++ L+ I +YPKEK+ L
Sbjct: 261 ARTFNGV--CLLCQENLLDLEETNLPVISLALMVTQPVPFFDQFLEGIESLNYPKEKLHL 318
Query: 1245 YIYNNQPFSIKNIQDFLQKHGKSYYTKRVINGVTEIGDREARNEAIEWNKARNVEFAFLM 1066
IY+N F +I+ F+ KH K Y T + E+ +R+ R A++ + ++ F +
Sbjct: 319 LIYSNVAFHDDDIKSFVNKHAKEYATAKFALSTDELDERQGRQLALDKARLHQSDYIFFV 378
Query: 1065 DGDAYFSEPKVIKDLIQYSKTYDVGIIAPMIGQPGKLFTNFWGAIAANGYYARSEDYMAI 886
D DA+ + +V+++L++ +K + +AP+ + +L++NFWGA++ GYYARS DY+ I
Sbjct: 379 DADAHIDDGEVLRELLRLNKQF----VAPIFSKHKELWSNFWGALSEGGYYARSHDYVDI 434
Query: 885 VKGNRVGYWNVPFITSAVLFNKEKLEAMKDAYSYNKNLDPDMSMCKFARDNGHFLYIDNE 706
VK +G +NVP +TS L K +A+ + K DPDM+MC+ R+ G F+Y N
Sbjct: 435 VKRELIGMFNVPHVTSIYLVKKTAFDAISFKH---KEFDPDMAMCESLRNAGIFMYASNL 491
Query: 705 KYYGFLIVSDEYAETVTEGKWHPEMWQIFENRELWEARYIHPGYHKIMEPEHVVDQACPD 526
+ +G L+ +D++ TVT P+ + +F N W +YIHP Y + + + Q CPD
Sbjct: 492 RIFGHLVNADDFNTTVTR----PDFYTLFSNEIDWTEKYIHPNYSLQLNESNKIQQPCPD 547
Query: 525 VYDFPLMSERFCEELIEEMEGFGRWSDGSNNDKRLAGGYENVPTRDIHMNQVGFERQWLY 346
VY F ++S+ FC++L+ ME WSDGSNND RL GGYE VPTRDIHM QVG ER +L
Sbjct: 548 VYWFQIVSDAFCDDLVAIMEAHNGWSDGSNNDNRLEGGYEAVPTRDIHMKQVGLERLYLK 607
Query: 345 FMDTYVRPVQEKTFIGYYHQPVESNMMFVVRYKPEEQPSLRPHHDASTFSIDIALNKKGR 166
F+ +VRP+QE+ F GY+H P + M F+VRY+P+EQPSLRPHHD+ST++I+IA+N+ G
Sbjct: 608 FLQMFVRPLQERAFTGYFHNPPRALMNFMVRYRPDEQPSLRPHHDSSTYTINIAMNRAGI 667
Query: 165 DYEGGGVRYIRYNCTVPADEVGYAMMFPGRLTHLHEGLATTKGTRYIMVSFINP 4
DY+GGG R+IRYNC+V + G+ +M PGRLTH HEGL T GTRYIM+SFI+P
Sbjct: 668 DYQGGGCRFIRYNCSVTDTKKGWMLMHPGRLTHYHEGLLVTNGTRYIMISFIDP 721
>gi|32307144|ref|NP_000293.2| lysyl hydroxylase precursor; lysine
hydroxylase [Homo sapiens]
gi|12038976|emb|CAC19722.1| dJ1077B9.1 (procollagen-lysine,
2-oxoglutarate 5-dioxygenase (lysine hydroxylase,
Ehlers-Danlos syndrome type VI)) [Homo sapiens]
gi|20149013|gb|AAM12752.1| lysyl hydroxylase [Homo sapiens]
Length = 727
Score = 637 bits (1642), Expect = 0.0
Identities = 313/714 (43%), Positives = 465/714 (64%), Gaps = 8/714 (1%)
Frame = -1
Query: 2121 LVVVTVATENTDGLKRLLESAKAFDINIEVLGLGEKWNGGDTRIEQGGGQKIRILSDWIE 1942
L+V+TVAT+ T+G +R SA+ F+ I+ LGLGE WN + GGGQK+R+L +E
Sbjct: 28 LLVLTVATKETEGFRRFKRSAQFFNYKIQALGLGEDWNV-EKGTSAGGGQKVRLLKKALE 86
Query: 1941 KYKDASDTMIMFVDAYDVVFNADSTTILRKFFEHYSEKRLLFGAEPFCWPDQSLAPEYPI 1762
K+ D D +I+F D+YDV+F + +L+KF + S+ ++F AE +PD+ L +YP+
Sbjct: 87 KHADKEDLVILFADSYDVLFASGPRELLKKFRQARSQ--VVFSAEELIYPDRRLETKYPV 144
Query: 1761 VEFGKRFLNSGLFMGYGPEMHKILKLKSVEDKDDDQLYYTMIYLDEKLRKELNMDLDSMS 1582
V GKRFL SG F+GY P + K++ +D D DQL+YT I+LD + R+++N+ LD
Sbjct: 145 VSDGKRFLGSGGFIGYAPNLSKLVAEWEGQDSDSDQLFYTKIFLDPEKREQINITLDHRC 204
Query: 1581 KIFQNLNGVIEDVELQFKEDGTPEAYNAAYNTKPLIVHGNGPSKSHLNYLGNYLGNRWNS 1402
+IFQNL+G +++V L+F E G A N AY+T P+++HGNGP+K LNYLGNY+ W
Sbjct: 205 RIFQNLDGALDEVVLKF-EMGHVRARNLAYDTLPVLIHGNGPTKLQLNYLGNYIPRFWTF 263
Query: 1401 QLGCRTCGLEVKE-----SEEVPLIALNLFISKPIPFIEEVLQKIAEFDYPKEKIALYIY 1237
+ GC C ++ E +P + + +FI +P PF+ Q++ YP++ + L+I+
Sbjct: 264 ETGCTVCDEGLRSLKGIGDEALPTVLVGVFIEQPTPFVSLFFQRLLRLHYPQKHMRLFIH 323
Query: 1236 NNQPFSIKNIQDFLQKHGKSYYTKRVINGVTEIGDREARNEAIEW-NKARNVEFAFLMDG 1060
N++ +++FL +HG Y + +++ + + +ARN + + R+ + F +D
Sbjct: 324 NHEQHHKAQVEEFLAQHGSEYQSVKLVGPEVRMANADARNMGADLCRQDRSCTYYFSVDA 383
Query: 1059 DAYFSEPKVIKDLIQYSKTYDVGIIAPMIGQPGKLFTNFWGAIAANGYYARSEDYMAIVK 880
D +EP ++ LIQ +K +IAP++ + G+L++NFWGA++A+GYYARSEDY+ IV+
Sbjct: 384 DVALTEPNSLRLLIQQNKN----VIAPLMTRHGRLWSNFWGALSADGYYARSEDYVDIVQ 439
Query: 879 GNRVGYWNVPFITSAVLFNKEKL--EAMKDAYSYNKNLDPDMSMCKFARDNGHFLYIDNE 706
G RVG WNVP+I++ L L E ++ LDPDM+ C R F+++ N
Sbjct: 440 GRRVGVWNVPYISNIYLIKGSALRGELQSSDLFHHSKLDPDMAFCANIRQQDVFMFLTNR 499
Query: 705 KYYGFLIVSDEYAETVTEGKWHPEMWQIFENRELWEARYIHPGYHKIMEPEHVVDQACPD 526
G L+ D Y T H ++W++F N E W+ +YIH Y K + + +V+ CPD
Sbjct: 500 HTLGHLLSLDSYRTT----HLHNDLWEVFSNPEDWKEKYIHQNYTKALAGK-LVETPCPD 554
Query: 525 VYDFPLMSERFCEELIEEMEGFGRWSDGSNNDKRLAGGYENVPTRDIHMNQVGFERQWLY 346
VY FP+ +E C+EL+EEME FG+WS G+N D R+ GGYENVPT DIHMNQ+GFER+W
Sbjct: 555 VYWFPIFTEVACDELVEEMEHFGQWSLGNNKDNRIQGGYENVPTIDIHMNQIGFEREWHK 614
Query: 345 FMDTYVRPVQEKTFIGYYHQPVESNMMFVVRYKPEEQPSLRPHHDASTFSIDIALNKKGR 166
F+ Y+ P+ EK + GYY + + ++ FVVRYKP+EQPSL PHHDASTF+I+IALN+ G
Sbjct: 615 FLLEYIAPMTEKLYPGYYTR-AQFDLAFVVRYKPDEQPSLMPHHDASTFTINIALNRVGV 673
Query: 165 DYEGGGVRYIRYNCTVPADEVGYAMMFPGRLTHLHEGLATTKGTRYIMVSFINP 4
DYEGGG R++RYNC++ A G+ +M PGRLTH HEGL TT+GTRYI VSF++P
Sbjct: 674 DYEGGGCRFLRYNCSIRAPRKGWTLMHPGRLTHYHEGLPTTRGTRYIAVSFVDP 727
>gi|400205|sp|Q02809|PLO1_HUMAN Procollagen-lysine,2-oxoglutarate
5-dioxygenase 1 precursor (Lysyl hydroxylase 1) (LH1)
gi|420086|pir||A38206 procollagen-lysine 5-dioxygenase (EC 1.14.11.4)
1 precursor - human
gi|190074|gb|AAA60116.1| lysyl hydroxylase
Length = 727
Score = 637 bits (1642), Expect = 0.0
Identities = 313/714 (43%), Positives = 465/714 (64%), Gaps = 8/714 (1%)
Frame = -1
Query: 2121 LVVVTVATENTDGLKRLLESAKAFDINIEVLGLGEKWNGGDTRIEQGGGQKIRILSDWIE 1942
L+V+TVAT+ T+G +R SA+ F+ I+ LGLGE WN + GGGQK+R+L +E
Sbjct: 28 LLVLTVATKETEGFRRFKRSAQFFNYKIQALGLGEDWNV-EKGTSAGGGQKVRLLKKALE 86
Query: 1941 KYKDASDTMIMFVDAYDVVFNADSTTILRKFFEHYSEKRLLFGAEPFCWPDQSLAPEYPI 1762
K+ D D +I+F D+YDV+F + +L+KF + S+ ++F AE +PD+ L +YP+
Sbjct: 87 KHADKEDLVILFTDSYDVLFASGPRELLKKFRQARSQ--VVFSAEELIYPDRRLETKYPV 144
Query: 1761 VEFGKRFLNSGLFMGYGPEMHKILKLKSVEDKDDDQLYYTMIYLDEKLRKELNMDLDSMS 1582
V GKRFL SG F+GY P + K++ +D D DQL+YT I+LD + R+++N+ LD
Sbjct: 145 VSDGKRFLGSGGFIGYAPNLSKLVAEWEGQDSDSDQLFYTKIFLDPEKREQINITLDHRC 204
Query: 1581 KIFQNLNGVIEDVELQFKEDGTPEAYNAAYNTKPLIVHGNGPSKSHLNYLGNYLGNRWNS 1402
+IFQNL+G +++V L+F E G A N AY+T P+++HGNGP+K LNYLGNY+ W
Sbjct: 205 RIFQNLDGALDEVVLKF-EMGHVRARNLAYDTLPVLIHGNGPTKLQLNYLGNYIPRFWTF 263
Query: 1401 QLGCRTCGLEVKE-----SEEVPLIALNLFISKPIPFIEEVLQKIAEFDYPKEKIALYIY 1237
+ GC C ++ E +P + + +FI +P PF+ Q++ YP++ + L+I+
Sbjct: 264 ETGCTVCDEGLRSLKGIGDEALPTVLVGVFIEQPTPFVSLFFQRLLRLHYPQKHMRLFIH 323
Query: 1236 NNQPFSIKNIQDFLQKHGKSYYTKRVINGVTEIGDREARNEAIEW-NKARNVEFAFLMDG 1060
N++ +++FL +HG Y + +++ + + +ARN + + R+ + F +D
Sbjct: 324 NHEQHHKAQVEEFLAQHGSEYQSVKLVGPEVRMANADARNMGADLCRQDRSCTYYFSVDA 383
Query: 1059 DAYFSEPKVIKDLIQYSKTYDVGIIAPMIGQPGKLFTNFWGAIAANGYYARSEDYMAIVK 880
D +EP ++ LIQ +K +IAP++ + G+L++NFWGA++A+GYYARSEDY+ IV+
Sbjct: 384 DVALTEPNSLRLLIQQNKN----VIAPLMTRHGRLWSNFWGALSADGYYARSEDYVDIVQ 439
Query: 879 GNRVGYWNVPFITSAVLFNKEKL--EAMKDAYSYNKNLDPDMSMCKFARDNGHFLYIDNE 706
G RVG WNVP+I++ L L E ++ LDPDM+ C R F+++ N
Sbjct: 440 GRRVGVWNVPYISNIYLIKGSALRGELQSSDLFHHSKLDPDMAFCANIRQQDVFMFLTNR 499
Query: 705 KYYGFLIVSDEYAETVTEGKWHPEMWQIFENRELWEARYIHPGYHKIMEPEHVVDQACPD 526
G L+ D Y T H ++W++F N E W+ +YIH Y K + + +V+ CPD
Sbjct: 500 HTLGHLLSLDSYRTT----HLHNDLWEVFSNPEDWKEKYIHQNYTKALAGK-LVETPCPD 554
Query: 525 VYDFPLMSERFCEELIEEMEGFGRWSDGSNNDKRLAGGYENVPTRDIHMNQVGFERQWLY 346
VY FP+ +E C+EL+EEME FG+WS G+N D R+ GGYENVPT DIHMNQ+GFER+W
Sbjct: 555 VYWFPIFTEVACDELVEEMEHFGQWSLGNNKDNRIQGGYENVPTIDIHMNQIGFEREWHK 614
Query: 345 FMDTYVRPVQEKTFIGYYHQPVESNMMFVVRYKPEEQPSLRPHHDASTFSIDIALNKKGR 166
F+ Y+ P+ EK + GYY + + ++ FVVRYKP+EQPSL PHHDASTF+I+IALN+ G
Sbjct: 615 FLLEYIAPMTEKLYPGYYTR-AQFDLAFVVRYKPDEQPSLMPHHDASTFTINIALNRVGV 673
Query: 165 DYEGGGVRYIRYNCTVPADEVGYAMMFPGRLTHLHEGLATTKGTRYIMVSFINP 4
DYEGGG R++RYNC++ A G+ +M PGRLTH HEGL TT+GTRYI VSF++P
Sbjct: 674 DYEGGGCRFLRYNCSIRAPRKGWTLMHPGRLTHYHEGLPTTRGTRYIAVSFVDP 727