Homology by BLASTX
BLASTX 2.2.4 [Aug-26-2002]
Query= F59A6_7
(4137 letters)
Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
1,967,186 sequences; 661,712,633 total letters
Score E
Sequences producing significant alignments: (bits) Value
gi|32563802|ref|NP_494925.2| neuronal SYmmetry defect NSY-1, Enh... 2546 0.0
gi|7504728|pir||T16511 hypothetical protein F59A6.1 - Caenorhabd... 2446 0.0
gi|39596795|emb|CAE59022.1| Hypothetical protein CBG02299 [Caeno... 2307 0.0
gi|48098524|ref|XP_392079.1| similar to CG4720-PA [Apis mellifera] 803 0.0
gi|23237772|dbj|BAC16514.1| DASK1 [Drosophila melanogaster] 793 0.0
gi|24648284|ref|NP_477089.2| CG4720-PA [Drosophila melanogaster]... 793 0.0
gi|27374208|gb|AAO00972.1| Pk92B-PA [Drosophila erecta] 789 0.0
gi|27374376|gb|AAO01114.1| Pk92B-PA [Drosophila pseudoobscura] 775 0.0
gi|27374347|gb|AAO01088.1| Pk92B-PA [Drosophila willistoni] 768 0.0
gi|31204665|ref|XP_311281.1| ENSANGP00000001618 [Anopheles gambi... 747 0.0
gi|42662661|ref|XP_372199.2| similar to MAP/ERK kinase kinase 5;... 718 0.0
gi|5174547|ref|NP_005914.1| mitogen-activated protein kinase kin... 713 0.0
gi|1805500|dbj|BAA12684.1| ASK1 [Homo sapiens] 711 0.0
gi|6678796|ref|NP_032606.1| mitogen activated protein kinase kin... 696 0.0
gi|45553423|ref|NP_996240.1| CG4720-PB [Drosophila melanogaster]... 689 0.0
gi|50730209|ref|XP_416808.1| PREDICTED: similar to mitogen-activ... 674 0.0
gi|47221132|emb|CAG05453.1| unnamed protein product [Tetraodon n... 669 0.0
gi|50742707|ref|XP_419725.1| PREDICTED: similar to mitogen-activ... 640 0.0
gi|7513152|pir||JE0363 mitogen-activated protein kinase kinase k... 607 e-172
gi|45827809|ref|NP_004663.3| mitogen-activated protein kinase ki... 605 e-171
gi|45421836|dbj|BAD12485.1| apoptosis signal-regulating kinase 2... 605 e-171
gi|33186928|ref|NP_057902.2| mitogen-activated protein kinase ki... 597 e-169
gi|34871782|ref|XP_232732.2| similar to apoptosis signal-regulat... 576 e-162
gi|6685614|sp|O95382|M3K6_HUMAN Mitogen-activated protein kinase... 531 e-149
gi|16198467|gb|AAH15914.1| MAP3K6 protein [Homo sapiens] 531 e-149
gi|3646067|emb|CAA19711.1| dJ325F22.1.1 (mitogen-activated prote... 521 e-146
gi|47077281|dbj|BAD18559.1| unnamed protein product [Homo sapiens] 453 e-125
gi|48717280|ref|NP_001001671.1| FLJ16518 protein [Homo sapiens] ... 435 e-120
gi|2133706|pir||JC4673 protein kinase (EC 2.7.1.37) 2B - fruit f... 399 e-109
gi|34852767|ref|XP_344799.1| similar to apoptosis signal-regulat... 352 6e-95
gi|47208224|emb|CAF91207.1| unnamed protein product [Tetraodon n... 275 7e-72
gi|47222410|emb|CAG12930.1| unnamed protein product [Tetraodon n... 268 6e-70
gi|2342423|dbj|BAA21855.1| NPK1-related protein kinase 1S [Arabi... 203 3e-50
gi|2342421|dbj|BAA21854.1| NPK1-related protein kinase 1L [Arabi... 200 2e-49
gi|30680907|ref|NP_563832.2| NPK1-related protein kinase, putati... 200 2e-49
gi|4028547|gb|AAC97114.1| MEK kinase alpha [Dictyostelium discoi... 196 3e-48
gi|477094|pir||A48084 STE11 protein kinase homolog NPK1 - common... 192 6e-47
gi|50760598|ref|XP_418076.1| PREDICTED: similar to mitogen-activ... 192 6e-47
gi|456309|dbj|BAA05648.1| protein kinase [Nicotiana tabacum] 192 6e-47
gi|42562761|ref|NP_175894.2| NPK1-related protein kinase, putati... 189 4e-46
gi|46577122|sp|Q9FZ36|M3K2_ARATH Mitogen-activated protein kinas... 189 4e-46
gi|49387653|dbj|BAD25847.1| putative protein kinase [Oryza sativ... 189 5e-46
gi|38345202|emb|CAE02897.2| OSJNBa0015K02.14 [Oryza sativa (japo... 189 5e-46
gi|38345839|emb|CAD41079.2| OSJNBa0084K11.3 [Oryza sativa (japon... 188 1e-45
gi|2342425|dbj|BAA21856.1| NPK1-related protein kinase 2 [Arabid... 188 1e-45
gi|7542557|gb|AAF63496.1| protein kinase MEKK2b [Homo sapiens] 188 1e-45
gi|47217818|emb|CAG07232.1| unnamed protein product [Tetraodon n... 187 2e-45
gi|34878676|ref|XP_226073.2| mitogen activated protein kinase ki... 187 2e-45
gi|33146554|dbj|BAC79731.1| putative MAP3K protein kinase(Mitoge... 187 2e-45
gi|22760820|dbj|BAC11348.1| unnamed protein product [Homo sapiens] 186 3e-45
gi|50750890|ref|XP_426605.1| PREDICTED: similar to hypothetical ... 186 3e-45
gi|19113917|ref|NP_593005.1| serine/threonine-protein kinase mhk... 186 3e-45
gi|15230612|ref|NP_187254.1| NPK1-related protein kinase, putati... 186 4e-45
gi|15231270|ref|NP_187962.1| MAP3K epsilon protein kinase [Arabi... 186 5e-45
gi|6685620|sp|Q9Y2U5|M3K2_HUMAN Mitogen-activated protein kinase... 185 7e-45
gi|3549652|emb|CAA12272.1| MAP3K epsilon protein kinase [Arabido... 185 9e-45
gi|34873993|ref|XP_221034.2| similar to hypothetical protein [Ra... 184 2e-44
gi|2499640|sp|Q99759|M3K3_HUMAN Mitogen-activated protein kinase... 184 2e-44
gi|42794765|ref|NP_002392.2| mitogen-activated protein kinase ki... 184 2e-44
gi|14249913|gb|AAH08336.1| Unknown (protein for IMAGE:3506235) [... 184 2e-44
gi|3688193|emb|CAA08995.1| MAP3K alpha 1 protein kinase [Brassic... 184 2e-44
gi|42794767|ref|NP_976226.1| mitogen-activated protein kinase ki... 184 2e-44
gi|6754628|ref|NP_036076.1| mitogen activated protein kinase kin... 184 2e-44
gi|38344069|emb|CAD40821.2| OSJNBa0006B20.13 [Oryza sativa (japo... 184 2e-44
gi|33468949|ref|NP_036077.1| mitogen activated protein kinase ki... 184 2e-44
gi|12322153|gb|AAG51109.1| NPK1-related protein kinase, putative... 184 2e-44
gi|15231910|ref|NP_187455.1| protein kinase, putative [Arabidops... 183 3e-44
gi|21735556|ref|NP_006600.2| mitogen-activated protein kinase ki... 183 3e-44
gi|16930437|gb|AAL31904.1| At1g53570/F22G10_18 [Arabidopsis thal... 183 3e-44
gi|5824350|emb|CAB54520.1| MAP3K epsilon 1 protein kinase [Brass... 183 3e-44
gi|18404528|ref|NP_564635.1| mitogen-activated protein kinase ki... 183 3e-44
gi|4204912|gb|AAD10848.1| MEK kinase [Arabidopsis thaliana] 183 3e-44
gi|30695537|ref|NP_849803.1| mitogen-activated protein kinase ki... 182 4e-44
gi|6979343|gb|AAF34436.1| similar to mitogen-activated protein k... 182 6e-44
gi|50750638|ref|XP_422075.1| PREDICTED: similar to protein kinas... 182 6e-44
gi|50292987|ref|XP_448926.1| unnamed protein product [Candida gl... 182 6e-44
gi|49069976|ref|XP_399277.1| hypothetical protein UM01662.1 [Ust... 182 6e-44
gi|45861623|gb|AAS78640.1| MAP3Ka [Lycopersicon esculentum] 181 1e-43
gi|47218565|emb|CAG10264.1| unnamed protein product [Tetraodon n... 181 1e-43
gi|47200315|emb|CAF89255.1| unnamed protein product [Tetraodon n... 181 1e-43
gi|6322366|ref|NP_012440.1| Mitogen-activated protein (MAP) kina... 181 2e-43
gi|3415|emb|CAA42788.1| protein kinase [Saccharomyces cerevisiae] 181 2e-43
gi|218490|dbj|BAA01226.1| Ssp31 protein kinase [Saccharomyces ce... 181 2e-43
gi|45861621|gb|AAS78639.1| MAP3Ka [Nicotiana benthamiana] 181 2e-43
gi|50251372|dbj|BAD28399.1| putative MAP3K alpha 1 protein kinas... 179 4e-43
gi|37573087|dbj|BAC98657.1| putative protein kinase [Oryza sativ... 179 5e-43
gi|45198610|ref|NP_985639.1| AFR092Wp [Eremothecium gossypii] >g... 179 6e-43
gi|45476486|dbj|BAD12492.1| mitogen-activated kinase kinase kina... 178 8e-43
gi|34915394|ref|NP_919154.1| putative MAP3K protein kinase(Mitog... 178 1e-42
gi|25387031|pir||T52621 mitogen-activated protein kinase MAP3K [... 178 1e-42
gi|18425121|ref|NP_569040.1| protein kinase family protein [Arab... 178 1e-42
gi|15982852|gb|AAL09773.1| AT5g66850/MUD21_11 [Arabidopsis thali... 178 1e-42
gi|46389856|dbj|BAD15457.1| putative MEK kinase [Oryza sativa (j... 178 1e-42
gi|9758135|dbj|BAB08627.1| MAP protein kinase [Arabidopsis thali... 177 2e-42
gi|29250802|gb|EAA42290.1| GLP_440_20077_14564 [Giardia lamblia ... 177 2e-42
gi|50419825|ref|XP_458444.1| unnamed protein product [Debaryomyc... 177 2e-42
gi|46438606|gb|EAK97934.1| hypothetical protein CaO19.12629 [Can... 176 5e-42
gi|34904934|ref|NP_913814.1| putative protein kinase [Oryza sati... 175 7e-42
gi|7493822|pir||T30565 MAP kinase kinase kinase - yeast (Kluyver... 175 9e-42
gi|50311385|ref|XP_455717.1| unnamed protein product [Kluyveromy... 175 9e-42
gi|11119233|gb|AAG30572.1| mekk [Pneumocystis carinii] 175 9e-42
gi|38073358|ref|XP_136210.4| similar to FLJ23074 protein [Mus mu... 174 2e-41
gi|38110684|gb|EAA56368.1| hypothetical protein MG06339.4 [Magna... 173 4e-41
gi|32411113|ref|XP_326037.1| hypothetical protein ( (AF034090) M... 173 4e-41
gi|38049268|gb|AAR10436.1| YDA [Arabidopsis thaliana] 173 4e-41
gi|15222512|ref|NP_176557.1| protein kinase, putative [Arabidops... 173 4e-41
gi|46438961|gb|EAK98284.1| hypothetical protein CaO19.11257 [Can... 172 5e-41
gi|47223394|emb|CAG04255.1| unnamed protein product [Tetraodon n... 171 1e-40
gi|2654103|gb|AAC21676.1| MAPKK kinase [Neurospora crassa] 171 1e-40
gi|25777806|gb|AAN75612.1| STE11 [Cryptococcus neoformans var. n... 170 3e-40
gi|23664286|gb|AAN39295.1| MAP kinase kinase kinase [Cryptococcu... 170 3e-40
gi|25573212|gb|AAN75180.1| STE11 [Cryptococcus neoformans var. g... 169 7e-40
gi|32400274|emb|CAE00640.1| putative mitogen-activated protein k... 168 9e-40
gi|46122213|ref|XP_385660.1| hypothetical protein FG05484.1 [Gib... 167 1e-39
gi|50255788|gb|EAL18520.1| hypothetical protein CNBJ1620 [Crypto... 167 2e-39
gi|2131084|emb|CAA89388.1| BCK1 [Saccharomyces cerevisiae] 166 4e-39
gi|50555544|ref|XP_505180.1| hypothetical protein [Yarrowia lipo... 166 6e-39
gi|3688209|emb|CAA08997.1| MAP3K beta 1 protein kinase [Brassica... 165 7e-39
gi|46123897|ref|XP_386502.1| hypothetical protein FG06326.1 [Gib... 165 1e-38
gi|32421133|ref|XP_331010.1| hypothetical protein [Neurospora cr... 164 1e-38
gi|25573177|gb|AAN75153.1| STE11 [Cryptococcus neoformans var. g... 164 1e-38
gi|6531993|gb|AAF15541.1| septation [Aspergillus nidulans] 164 2e-38
gi|11096132|gb|AAG30205.1| Ste11alpha protein [Filobasidiella ne... 164 2e-38
gi|25956302|gb|AAN75716.1| STE11 [Cryptococcus neoformans var. n... 164 2e-38
gi|18699013|gb|AAL77223.1| Bck1-like MAP kinase kinase kinase [P... 164 2e-38
gi|15236515|ref|NP_192590.1| mitogen-activated protein kinase ki... 164 2e-38
gi|1255448|dbj|BAA09057.1| mitogen-activated protein kinase [Ara... 164 2e-38
gi|34879709|ref|XP_222618.2| similar to hypothetical protein FLJ... 163 3e-38
gi|50285925|ref|XP_445391.1| unnamed protein product [Candida gl... 163 3e-38
gi|34902116|ref|NP_912404.1| unknown protein [Oryza sativa (japo... 163 3e-38
gi|17064766|gb|AAL32537.1| Unknown protein [Arabidopsis thaliana... 162 6e-38
gi|25402508|pir||H86221 hypothetical protein [imported] - Arabid... 162 6e-38
gi|11358501|pir||T51625 MAP3K alpha protein kinase (EC 2.7.1.-) ... 162 8e-38
gi|19570058|gb|AAL92350.1| similar to Emericella nidulans (Asper... 162 8e-38
gi|38102381|gb|EAA49225.1| hypothetical protein MG00883.4 [Magna... 161 1e-37
gi|50555946|ref|XP_505381.1| hypothetical protein [Yarrowia lipo... 161 1e-37
gi|49095126|ref|XP_409024.1| hypothetical protein AN4887.2 [Aspe... 161 1e-37
gi|32420127|ref|XP_330507.1| hypothetical protein [Neurospora cr... 160 2e-37
gi|50732199|ref|XP_418525.1| PREDICTED: similar to Mitogen-activ... 160 2e-37
gi|9295113|gb|AAF86841.1| pheromone-responsive MAPKK kinase Ubc4... 159 4e-37
gi|24637970|gb|AAN63948.1| MAPKK kinase Kpp4 [Ustilago maydis] 159 4e-37
gi|38101581|gb|EAA48525.1| hypothetical protein MG00183.4 [Magna... 159 4e-37
gi|49075642|ref|XP_401873.1| hypothetical protein UM04258.1 [Ust... 159 4e-37
gi|50305241|ref|XP_452580.1| unnamed protein product [Kluyveromy... 159 5e-37
gi|46106086|ref|XP_380584.1| hypothetical protein FG00408.1 [Gib... 159 7e-37
gi|47214676|emb|CAF97200.1| unnamed protein product [Tetraodon n... 157 2e-36
gi|7494102|pir||T14616 hypothetical protein - Trypanosoma cruzi ... 157 2e-36
gi|37550279|ref|XP_042066.7| mitogen-activated protein kinase ki... 157 2e-36
gi|50761493|ref|XP_424734.1| PREDICTED: similar to Mitogen-activ... 157 2e-36
gi|8488988|sp|Q13233|M3K1_HUMAN Mitogen-activated protein kinase... 157 2e-36
gi|50412914|ref|XP_457180.1| unnamed protein product [Debaryomyc... 156 3e-36
gi|34881602|ref|XP_229143.2| similar to serine/threonine protein... 156 5e-36
gi|46442862|gb|EAL02148.1| hypothetical protein CaO19.844 [Candi... 156 5e-36
gi|1143820|gb|AAA85038.1| MEKK1 155 6e-36
gi|293730|gb|AAA97500.1| MEK Kinase 155 6e-36
gi|423499|pir||A46212 MEK kinase - mouse 155 6e-36
gi|33859656|ref|NP_036075.1| mitogen activated protein kinase ki... 155 6e-36
gi|1711551|sp|P23561|ST11_YEAST Serine/threonine-protein kinase ... 155 8e-36
gi|50285323|ref|XP_445090.1| unnamed protein product [Candida gl... 155 8e-36
gi|15236511|ref|NP_192588.1| mitogen-activated protein kinase, p... 155 8e-36
gi|2984701|gb|AAC08005.1| NPK-1 protein kinase homolog [Trypanos... 155 8e-36
gi|6323394|ref|NP_013466.1| Signal transducing MEK kinase involv... 155 8e-36
gi|115195|sp|P28829|BYR2_SCHPO Protein kinase byr2 (Protein kina... 155 1e-35
gi|19114476|ref|NP_593564.1| putative Ste20-like serine threonin... 155 1e-35
gi|19526920|ref|NP_598490.1| Mst3 and SOK1-related kinase [Mus m... 155 1e-35
gi|16758760|ref|NP_446339.1| mitogen activated protein kinase ki... 155 1e-35
gi|19112506|ref|NP_595714.1| protein kinase [Schizosaccharomyces... 155 1e-35
gi|38103666|gb|EAA50341.1| hypothetical protein MG04100.4 [Magna... 154 1e-35
gi|49068094|ref|XP_398336.1| hypothetical protein UM00721.1 [Ust... 154 1e-35
gi|15225692|ref|NP_180810.1| protein kinase family protein [Arab... 154 1e-35
gi|34911466|ref|NP_917080.1| NPK1-related protein kinase-like pr... 154 1e-35
gi|19423926|gb|AAL87297.1| unknown protein [Arabidopsis thaliana] 154 2e-35
gi|50543226|ref|XP_499779.1| hypothetical protein [Yarrowia lipo... 154 2e-35
gi|15236903|ref|NP_194419.1| protein kinase family protein [Arab... 154 2e-35
gi|49089378|ref|XP_406406.1| hypothetical protein AN2269.2 [Aspe... 154 2e-35
gi|14574085|gb|AAK68326.1| Hypothetical protein F14H12.4a [Caeno... 154 2e-35
gi|17550602|ref|NP_508741.1| protein kinase and rhodopsin-like G... 154 2e-35
gi|14574086|gb|AAK68327.1| Hypothetical protein F14H12.4b [Caeno... 154 2e-35
gi|17550604|ref|NP_508742.1| protein kinase (XE950) [Caenorhabdi... 154 2e-35
gi|15011880|ref|NP_057626.2| serine/threonine protein kinase MAS... 154 2e-35
gi|25151431|ref|NP_508743.2| STE20-like kinase MST family member... 154 2e-35
gi|47228941|emb|CAG09456.1| unnamed protein product [Tetraodon n... 153 3e-35
gi|50304331|ref|XP_452115.1| unnamed protein product [Kluyveromy... 153 3e-35
gi|39597868|emb|CAE68560.1| Hypothetical protein CBG14395 [Caeno... 153 4e-35
gi|50419083|ref|XP_458064.1| unnamed protein product [Debaryomyc... 153 4e-35
gi|19113132|ref|NP_596340.1| cell division control protein 7 [Sc... 152 5e-35
gi|22761053|dbj|BAC11435.1| unnamed protein product [Homo sapiens] 152 5e-35
gi|46436568|gb|EAK95928.1| hypothetical protein CaO19.11029 [Can... 152 5e-35
gi|46436503|gb|EAK95864.1| hypothetical protein CaO19.3545 [Cand... 152 5e-35
gi|50741728|ref|XP_419617.1| PREDICTED: similar to mitogen-activ... 152 7e-35
gi|49116766|gb|AAH73258.1| Unknown (protein for MGC:80614) [Xeno... 152 8e-35
gi|41107636|gb|AAH65378.1| STK24 protein [Homo sapiens] 152 8e-35
gi|23274191|gb|AAH35578.1| STK24 protein [Homo sapiens] 152 8e-35
gi|2582413|gb|AAB82560.1| STE20-like kinase 3 [Homo sapiens] 152 8e-35
gi|20070158|ref|NP_003567.2| serine/threonine kinase 24 (STE20 h... 152 8e-35
gi|33304141|gb|AAQ02578.1| serine/threonine kinase 24 [synthetic... 151 1e-34
gi|47215372|emb|CAG02188.1| unnamed protein product [Tetraodon n... 151 1e-34
gi|6324358|ref|NP_014428.1| Suppressor of Sensor Kinase (SLN1); ... 151 1e-34
gi|49071140|ref|XP_399859.1| hypothetical protein UM02244.1 [Ust... 150 2e-34
gi|45190826|ref|NP_985080.1| AER223Cp [Eremothecium gossypii] >g... 150 2e-34
gi|11358511|pir||T51736 mitogen-activated protein kinase MAP3K b... 150 2e-34
gi|17569069|ref|NP_509747.1| abnormal cell MIGration MIG-15, ser... 150 3e-34
gi|6031180|ref|NP_006715.1| mitogen-activated protein kinase kin... 150 3e-34
gi|1524361|emb|CAA69030.1| protein kinase [Schizosaccharomyces p... 150 3e-34
gi|2065438|emb|CAA72718.1| Wak1 protein [Schizosaccharomyces pombe] 150 3e-34
gi|6580349|emb|CAB63417.1| Hypothetical protein ZC504.4b [Caenor... 150 3e-34
gi|5803088|ref|NP_005913.1| mitogen-activated protein kinase kin... 150 3e-34
gi|27529700|dbj|BAA13204.2| KIAA0213 [Homo sapiens] 150 3e-34
gi|19114469|ref|NP_593557.1| mitogen-activated protein kinase wi... 150 3e-34
gi|6319328|ref|NP_009411.1| Protein kinase of the Mitotic Exit N... 150 3e-34
gi|399197|sp|P27636|CC15_YEAST Cell division control protein 15 ... 150 3e-34
gi|14530701|emb|CAC42384.1| Hypothetical protein ZC504.4c [Caeno... 150 3e-34
gi|7959712|gb|AAF71029.1| PRO0412 [Homo sapiens] 150 3e-34
gi|15232528|ref|NP_188140.1| protein kinase, putative [Arabidops... 149 4e-34
gi|38014493|gb|AAH60493.1| MGC68762 protein [Xenopus laevis] 149 4e-34
gi|49457448|emb|CAG47023.1| STK24 [Homo sapiens] 149 4e-34
gi|12328814|ref|NP_067395.1| serine/threonine kinase 4; STE20-li... 149 4e-34
gi|50256844|gb|EAL19562.1| hypothetical protein CNBG1910 [Crypto... 149 4e-34
gi|46122713|ref|XP_385910.1| hypothetical protein FG05734.1 [Gib... 149 4e-34
gi|21703922|ref|NP_663440.1| serine/threonine protein kinase 24 ... 149 6e-34
gi|49086562|ref|XP_405317.1| hypothetical protein AN1180.2 [Aspe... 149 6e-34
gi|5454096|ref|NP_006273.1| serine/threonine kinase 4; mammalian... 149 6e-34
gi|37747465|gb|AAH58916.1| STK4 protein [Homo sapiens] 149 6e-34
gi|7671654|emb|CAB89421.1| dJ1069P2.1.1 (serine/threonine kinase... 149 6e-34
gi|11877295|emb|CAB94025.2| MAP kinase [Leishmania major] 149 6e-34
gi|37530786|ref|NP_919695.1| putative NPK1-related protein kinas... 149 7e-34
gi|47939709|gb|AAH72113.1| MGC79096 protein [Xenopus laevis] 149 7e-34
gi|41469440|gb|AAS07241.1| putative protein kinase [Oryza sativa... 149 7e-34
gi|10383805|ref|NP_009998.2| functionally redundant with, and ho... 149 7e-34
gi|28393793|gb|AAO42306.1| putative mitogen-activated protein ki... 149 7e-34
gi|15236509|ref|NP_192587.1| mitogen-activated protein kinase, p... 149 7e-34
gi|34860670|ref|XP_230833.2| similar to STE20-like kinase MST1 [... 148 9e-34
gi|50745734|ref|XP_420219.1| PREDICTED: similar to serine/threon... 148 9e-34
gi|18409220|ref|NP_564955.1| serine/threonine protein kinase, pu... 148 9e-34
gi|13929032|ref|NP_113923.1| serine/threonine kinase 3; serine/t... 148 1e-33
gi|47229349|emb|CAF99337.1| unnamed protein product [Tetraodon n... 147 2e-33
gi|50555486|ref|XP_505151.1| hypothetical protein [Yarrowia lipo... 147 2e-33
gi|45190867|ref|NP_985121.1| AER264Cp [Eremothecium gossypii] >g... 147 2e-33
gi|41054445|ref|NP_955966.1| serine/threonine kinase 3 (STE20 ho... 147 2e-33
gi|5454094|ref|NP_006272.1| serine/threonine kinase 3 (STE20 hom... 147 2e-33
gi|45361343|ref|NP_989249.1| hypothetical protein MGC75656 [Xeno... 147 3e-33
gi|9790103|ref|NP_062609.1| serine/threonine kinase 3 (Ste20, ye... 147 3e-33
gi|6730645|gb|AAF27066.1| F4N2.17 [Arabidopsis thaliana] 147 3e-33
gi|49094122|ref|XP_408522.1| hypothetical protein AN4385.2 [Aspe... 147 3e-33
gi|46577548|sp|Q9JI10|STK3_MOUSE Serine/threonine-protein kinase... 147 3e-33
gi|50758675|ref|XP_417365.1| PREDICTED: similar to STE20-like ki... 146 4e-33
gi|21326113|gb|AAM47579.1| putative serine/ threonine kinase [So... 146 4e-33
gi|6754630|ref|NP_036078.1| mitogen activated protein kinase kin... 146 5e-33
gi|47202736|emb|CAF88126.1| unnamed protein product [Tetraodon n... 146 5e-33
gi|50304857|ref|XP_452384.1| unnamed protein product [Kluyveromy... 146 5e-33
gi|6685609|sp|O08648|M3K4_MOUSE Mitogen-activated protein kinase... 146 5e-33
gi|1117791|gb|AAA83254.1| MST1 146 5e-33
gi|37590139|gb|AAH58719.1| Map3k4 protein [Mus musculus] 146 5e-33
gi|20977846|gb|AAM33376.1| MEK4b [Mus musculus] 146 5e-33
gi|28972095|dbj|BAC65501.1| mKIAA0213 protein [Mus musculus] 146 5e-33
gi|30851421|gb|AAH52474.1| Map4k6-pending protein [Mus musculus] 146 5e-33
gi|15240456|ref|NP_200320.1| protein kinase family protein [Arab... 145 6e-33
gi|33304055|gb|AAQ02535.1| serine/threonine kinase 3 [synthetic ... 145 6e-33
gi|27753948|emb|CAD57714.1| Hypothetical protein ZC504.4d [Caeno... 145 6e-33
gi|46577700|sp|Q13188|STK3_HUMAN Serine/threonine-protein kinase... 145 6e-33
gi|32405646|ref|XP_323436.1| hypothetical protein [Neurospora cr... 145 6e-33
gi|34784406|gb|AAH56650.1| Unknown (protein for MGC:68239) [Mus ... 145 8e-33
gi|22035604|ref|NP_663719.1| mitogen-activated protein kinase ki... 145 8e-33
gi|12278524|gb|AAG49001.1| putative serine/threonine kinase [Hor... 145 8e-33
gi|22035606|ref|NP_663720.1| mitogen-activated protein kinase ki... 145 8e-33
gi|4322936|gb|AAD16137.1| HPK/GCK-like kinase HGK [Homo sapiens] 145 8e-33
gi|22035602|ref|NP_004825.2| mitogen-activated protein kinase ki... 145 8e-33
gi|29427585|sp|O95819|M4K4_HUMAN Mitogen-activated protein kinas... 145 8e-33
gi|28207195|gb|AAO32626.1| Ste20 group protein kinase HGK [Homo ... 145 8e-33
gi|3819699|emb|CAA08758.1| BnMAP4K alpha2 [Brassica napus] 145 8e-33
gi|47205700|emb|CAF96240.1| unnamed protein product [Tetraodon n... 145 8e-33
gi|6110357|gb|AAF03786.1| Traf2 and NCK interacting kinase, spli... 145 1e-32
gi|12061243|gb|AAG45491.1| 36I5.3 [Oryza sativa (japonica cultiv... 145 1e-32
gi|6110360|gb|AAF03787.1| Traf2 and NCK interacting kinase, spli... 145 1e-32
gi|15220416|ref|NP_172003.1| protein kinase family protein [Arab... 145 1e-32
gi|6110365|gb|AAF03789.1| Traf2 and NCK interacting kinase, spli... 145 1e-32
gi|6110355|gb|AAF03785.1| Traf2 and NCK interacting kinase, spli... 145 1e-32
gi|50417480|gb|AAH77350.1| Unknown (protein for MGC:81192) [Xeno... 145 1e-32
gi|20521083|dbj|BAA25477.2| KIAA0551 protein [Homo sapiens] 145 1e-32
gi|6110352|gb|AAF03784.1| Traf2 and NCK interacting kinase, spli... 145 1e-32
gi|50418771|ref|XP_457906.1| unnamed protein product [Debaryomyc... 145 1e-32
gi|29728547|ref|XP_039796.7| KIAA0551 protein [Homo sapiens] >gn... 145 1e-32
gi|38077770|ref|XP_130797.3| Traf2 and NCK interacting kinase-li... 145 1e-32
gi|6110350|gb|AAF03783.1| Traf2 and NCK interacting kinase, spli... 145 1e-32
gi|6110362|gb|AAF03788.1| Traf2 and NCK interacting kinase, spli... 145 1e-32
gi|32171940|gb|AAP72037.1| MAP kinase kinase kinase Czk3 [Cercos... 145 1e-32
gi|28829340|gb|AAO51882.1| similar to Oryza sativa (Rice). 36I5.... 144 1e-32
gi|50540506|ref|NP_001002717.1| zgc:91798 [Danio rerio] >gnl|BL_... 144 1e-32
gi|26984581|emb|CAD59176.1| SI:dZ198M22.1 (novel protein similar... 144 1e-32
gi|29469131|gb|AAO49813.1| STE20-like kinase [Squalus acanthias] 144 1e-32
gi|28493842|ref|XP_148586.2| p21-activated kinase 2 [Mus musculu... 144 1e-32
gi|2499648|sp|Q64303|PAK2_RAT Serine/threonine-protein kinase PA... 144 1e-32
gi|30697816|ref|NP_849865.1| serine/threonine protein kinase, pu... 144 1e-32
gi|2136032|pir||S58682 protein kinase, p21-activated (EC 2.7.1.-... 144 2e-32
gi|50422805|ref|XP_459979.1| unnamed protein product [Debaryomyc... 144 2e-32
gi|7446456|pir||T01836 serine/threonine-specific protein kinase ... 144 2e-32
gi|47117898|sp|Q61036|PAK3_MOUSE Serine/threonine-protein kinase... 144 2e-32
gi|47117186|sp|Q7YQL3|PAK3_PONPY Serine/threonine-protein kinase... 144 2e-32
gi|37530788|ref|NP_919696.1| putative NPK1-related protein kinas... 144 2e-32
gi|18496653|gb|AAL74185.1| putative serine/threonine kinase [Tri... 144 2e-32
gi|31543458|ref|NP_445758.2| p21-activated kinase 2 [Rattus norv... 144 2e-32
gi|7677056|gb|AAF67008.1| P21-activated kinase 3 [Homo sapiens] 144 2e-32
gi|21953248|emb|CAD42790.1| p21-activated kinase 3 [Mus musculus... 144 2e-32
gi|4505601|ref|NP_002569.1| p21-activated kinase 3; CDKN1A; p21-... 144 2e-32
gi|3420949|gb|AAC31969.1| Cdc42/Rac effector kinase; PAK-3 [Mus ... 144 2e-32
gi|9506947|ref|NP_062083.1| p21 (CDKN1A)-activated kinase 3; p21... 144 2e-32
gi|30316198|sp||P83510_1 [Segment 1 of 2] Traf2 and NCK interact... 144 2e-32
gi|5679324|gb|AAD46921.1| p21 GTPase-associated kinase 1 [Xenopu... 144 2e-32
gi|26334721|dbj|BAC31061.1| unnamed protein product [Mus musculus] 144 2e-32
gi|28882060|ref|NP_795712.1| mitogen-activated protein kinase ki... 143 3e-32
gi|29428007|sp|Q9JM52|M4K6_MOUSE Mitogen-activated protein kinas... 143 3e-32
gi|7710058|ref|NP_057922.1| mitogen-activated protein kinase kin... 143 3e-32
gi|2660696|gb|AAB88118.1| p21-activated kinase [Xenopus laevis] 143 3e-32
gi|24647605|ref|NP_650596.1| CG5169-PA [Drosophila melanogaster]... 143 3e-32
gi|25012570|gb|AAN71385.1| RE38276p [Drosophila melanogaster] 143 3e-32
gi|49118800|gb|AAH73247.1| Unknown (protein for IMAGE:5505767) [... 143 3e-32
gi|2499647|sp|Q29502|PAK2_RABIT Serine/threonine-protein kinase ... 143 3e-32
gi|3041712|sp|Q13177|PAK2_HUMAN Serine/threonine-protein kinase ... 143 3e-32
gi|32483399|ref|NP_002568.2| p21-activated kinase 2; S6/H4 kinas... 143 3e-32
gi|24266661|gb|AAN52281.1| Pak3 serine/threonine protein kinase;... 143 4e-32
gi|34911476|ref|NP_917085.1| NPK1-related protein kinase-like pr... 143 4e-32
gi|7657335|ref|NP_056531.1| misshapen/NIK-related kinase isoform... 142 5e-32
gi|3819697|emb|CAA08757.1| BnMAP4K alpha1 [Brassica napus] 142 5e-32
gi|24850117|ref|NP_733763.1| misshapen/NIK-related kinase isofor... 142 5e-32
gi|29427834|sp|Q8N4C8|M4K6_HUMAN Mitogen-activated protein kinas... 142 5e-32
gi|27436917|ref|NP_722549.2| misshapen/NIK-related kinase isofor... 142 5e-32
gi|47226834|emb|CAG06676.1| unnamed protein product [Tetraodon n... 142 5e-32
gi|28972093|dbj|BAC65500.1| mKIAA0204 protein [Mus musculus] 142 7e-32
gi|49256094|gb|AAH74181.1| Unknown (protein for MGC:82018) [Xeno... 142 7e-32
gi|26325440|dbj|BAC26474.1| unnamed protein product [Mus musculus] 142 7e-32
gi|4741823|gb|AAD28717.1| Ste20-related kinase SMAK [Mus musculus] 142 7e-32
gi|7106427|ref|NP_033315.1| STE20-like kinase; Ste20-related kin... 142 7e-32
gi|37748704|gb|AAH59992.1| MGC68680 protein [Xenopus laevis] 142 7e-32
gi|6754978|ref|NP_035165.1| p21 (CDKN1A)-activated kinase 1 [Mus... 142 9e-32
gi|40788907|dbj|BAA13195.2| KIAA0204 protein [Homo sapiens] 142 9e-32
gi|29126889|gb|AAH47762.1| SLK protein [Homo sapiens] 142 9e-32
gi|21707917|gb|AAH34417.1| FLJ23074 protein [Homo sapiens] 142 9e-32
gi|29126867|gb|AAH47885.1| SLK protein [Homo sapiens] 142 9e-32
gi|47212948|emb|CAF92625.1| unnamed protein product [Tetraodon n... 142 9e-32
gi|1944185|dbj|BAA19655.1| hSLK [Homo sapiens] 142 9e-32
gi|40787731|gb|AAH64804.1| SLK protein [Homo sapiens] 142 9e-32
gi|41281453|ref|NP_055535.2| serine/threonine kinase 2; Ste20-li... 142 9e-32
gi|47227037|emb|CAG05929.1| unnamed protein product [Tetraodon n... 142 9e-32
gi|42794769|ref|NP_002567.3| p21-activated kinase 1; p21/Cdc42/R... 141 1e-31
gi|15219212|ref|NP_175724.1| protein kinase, putative [Arabidops... 141 1e-31
gi|1168176|gb|AAB35358.1| mPAK-3=p21Cdc42/Rac activated kinase [... 141 1e-31
gi|24655509|ref|NP_611399.2| CG7097-PB [Drosophila melanogaster]... 141 1e-31
gi|17946559|gb|AAL49310.1| RH10407p [Drosophila melanogaster] 141 1e-31
gi|24655504|ref|NP_725863.1| CG7097-PA [Drosophila melanogaster]... 141 1e-31
gi|543451|pir||S40482 serine/threonine-specific protein kinase (... 141 1e-31
gi|8393901|ref|NP_058894.1| p21 (CDKN1A)-activated kinase 1; p21... 141 1e-31
gi|2499643|sp|Q13153|PAK1_HUMAN Serine/threonine-protein kinase ... 141 2e-31
gi|47218648|emb|CAG04977.1| unnamed protein product [Tetraodon n... 141 2e-31
gi|46445610|gb|EAL04878.1| hypothetical protein CaO19.4890 [Cand... 140 2e-31
gi|3334151|sp|O14427|CLA4_CANAL Serine/threonine-protein kinase ... 140 2e-31
gi|46445415|gb|EAL04684.1| hypothetical protein CaO19.12355 [Can... 140 2e-31
gi|6679060|ref|NP_032722.1| mitogen-activated protein kinase kin... 140 2e-31
gi|45383408|ref|NP_989705.1| serine/threonine kinase 25 [Gallus ... 140 2e-31
gi|29839687|sp|Q9SZ67|WR19_ARATH Probable WRKY transcription fac... 140 3e-31
gi|13376582|ref|NP_079328.1| hypothetical protein FLJ23074 [Homo... 140 3e-31
gi|3075511|gb|AAC24522.1| severin kinase [Dictyostelium discoideum] 140 3e-31
gi|7514128|pir||T18532 serine/threoine protein kinase - guinea p... 140 3e-31
gi|39585498|emb|CAE70581.1| Hypothetical protein CBG17239 [Caeno... 140 3e-31
gi|984305|gb|AAA75468.1| hPAK65 140 3e-31
gi|47222536|emb|CAG02901.1| unnamed protein product [Tetraodon n... 140 3e-31
gi|47482156|gb|AAH69613.1| P21-activated kinase 2 [Homo sapiens] 140 3e-31
gi|1335890|gb|AAC47094.1| serine/threonine kinase PAK homolog DPAK 140 3e-31
gi|17864254|ref|NP_524681.1| CG10295-PB [Drosophila melanogaster... 140 3e-31
gi|1336004|gb|AAB01209.1| p21-activated protein kinase 1 Dpak1 140 3e-31
gi|45185219|ref|NP_982936.1| ABL011Cp [Eremothecium gossypii] >g... 140 3e-31
gi|50731466|ref|XP_417275.1| PREDICTED: similar to Serine/threon... 140 3e-31
gi|50745958|ref|XP_420314.1| PREDICTED: similar to p21-activated... 140 3e-31
gi|9256908|pdb|1F3M|C Chain C, Crystal Structure Of Human Serine... 140 3e-31
gi|48097025|ref|XP_393668.1| similar to P21/Cdc42/Rac1-activated... 140 3e-31
gi|49071464|ref|XP_400021.1| hypothetical protein UM02406.1 [Ust... 140 3e-31
gi|1256422|gb|AAC50590.1| PAK1 139 4e-31
gi|31207237|ref|XP_312585.1| ENSANGP00000014818 [Anopheles gambi... 139 4e-31
gi|46125933|ref|XP_387520.1| hypothetical protein FG07344.1 [Gib... 139 4e-31
gi|32412696|ref|XP_326828.1| hypothetical protein ( (AL451017) r... 139 4e-31
gi|31201199|ref|XP_309547.1| ENSANGP00000012515 [Anopheles gambi... 139 6e-31
gi|29427386|sp|Q924I2|M4K3_RAT Mitogen-activated protein kinase ... 139 6e-31
gi|49096702|ref|XP_409811.1| hypothetical protein AN5674.2 [Aspe... 139 6e-31
gi|49078906|ref|XP_403158.1| hypothetical protein UM05543.1 [Ust... 139 6e-31
gi|21667042|gb|AAM73879.1| Ste20-like kinase Don3 [Ustilago maydis] 139 6e-31
gi|3265160|gb|AAC24716.1| p21 activated kinase 1B [Homo sapiens] 139 6e-31
gi|31234667|ref|XP_319097.1| ENSANGP00000022332 [Anopheles gambi... 139 6e-31
gi|6679205|ref|NP_032804.1| p21 (CDKN1A)-activated kinase 3; Cdc... 139 6e-31
gi|37778686|gb|AAO83391.1| GCK-like kinase MIK [Zea mays] 139 6e-31
gi|28839779|gb|AAH47865.1| MAP4K2 protein [Homo sapiens] 139 7e-31
gi|34877690|ref|XP_343633.1| similar to Ste20-like kinase [Rattu... 139 7e-31
gi|3114954|emb|CAA73555.1| Stress-responsive protein kinase (PRK... 139 7e-31
gi|22035600|ref|NP_004570.2| mitogen-activated protein kinase ki... 139 7e-31
gi|7513353|pir||S71886 Ste20-like protein kinase - human >gnl|BL... 139 7e-31
gi|21361358|ref|NP_006365.2| serine/threonine kinase 25; sterile... 139 7e-31
gi|16041809|gb|AAH15793.1| STK25 protein [Homo sapiens] 139 7e-31
gi|34576555|ref|NP_908938.1| serine/threonine kinase 25 [Rattus ... 139 7e-31
gi|41351169|gb|AAH65603.1| P21/Cdc42/Rac1-activated kinase 1 [Da... 139 7e-31
gi|41152203|ref|NP_958485.1| p21/Cdc42/Rac1-activated kinase 1 [... 139 7e-31
gi|17505356|ref|NP_491682.1| mitogen activated protein kinase ki... 138 1e-30
gi|34911474|ref|NP_917084.1| NPK1-related protein kinase-like pr... 138 1e-30
gi|17505358|ref|NP_491683.1| mitogen activated protein kinase ki... 138 1e-30
gi|6678800|ref|NP_033032.1| mitogen activated protein kinase kin... 138 1e-30
gi|34861505|ref|XP_219531.2| similar to Rab8-interacting protein... 138 1e-30
gi|50746038|ref|XP_420349.1| PREDICTED: similar to mKIAA0687 pro... 138 1e-30
gi|9507155|ref|NP_062222.1| serine/threonine kinase 2; STE20-lik... 138 1e-30
gi|12230009|sp|Q9Z2W1|ST25_MOUSE Serine/threonine-protein kinase... 138 1e-30
gi|47087323|ref|NP_998642.1| zgc:66137 [Danio rerio] >gnl|BL_ORD... 138 1e-30
gi|37722427|gb|AAN72832.1| LOK-like protein kinase [Schistosoma ... 138 1e-30
gi|41054391|ref|NP_955997.1| misshapen; wu:fc52d11 [Danio rerio]... 138 1e-30
gi|50304375|ref|XP_452137.1| unnamed protein product [Kluyveromy... 138 1e-30
gi|50258866|gb|EAL21549.1| hypothetical protein CNBD0170 [Crypto... 138 1e-30
gi|17558624|ref|NP_505809.1| kinase 1 (5L518) [Caenorhabditis el... 138 1e-30
gi|47122900|gb|AAH70568.1| MGC80023 protein [Xenopus laevis] 138 1e-30
gi|48097848|ref|XP_393907.1| similar to ENSANGP00000022332 [Apis... 138 1e-30
gi|31217074|ref|XP_316357.1| ENSANGP00000004215 [Anopheles gambi... 138 1e-30
gi|17558622|ref|NP_505810.1| kinase 4 (5L518) [Caenorhabditis el... 138 1e-30
gi|50550123|ref|XP_502534.1| hypothetical protein [Yarrowia lipo... 138 1e-30
gi|45593475|sp|Q12851|M4K2_HUMAN Mitogen-activated protein kinas... 138 1e-30
gi|11359193|pir||T50298 MAP kinase kinase kinase Win1p [imported... 137 2e-30
gi|42717987|gb|AAF82310.3| PakC [Dictyostelium discoideum] 137 2e-30
gi|25153836|ref|NP_505311.2| germinal Center Kinase (70.5 kD) (g... 137 2e-30
gi|50256006|gb|EAL18735.1| hypothetical protein CNBI3210 [Crypto... 137 2e-30
gi|50811830|ref|NP_998473.1| serine/threonine kinase 25 [Danio r... 137 2e-30
gi|15214332|sp|O74304|WIN1_SCHPO MAP kinase kinase kinase win1 >... 137 2e-30
gi|47215043|emb|CAF95897.1| unnamed protein product [Tetraodon n... 137 2e-30
gi|34395227|dbj|BAC83751.1| putative MAP4 kinase [Oryza sativa (... 137 2e-30
gi|45552895|ref|NP_995974.1| CG16973-PB [Drosophila melanogaster... 137 2e-30
gi|45552889|ref|NP_995971.1| CG16973-PE [Drosophila melanogaster... 137 2e-30
gi|7512005|pir||JC6316 probable protein kinase (EC 2.7.1.-) - fr... 137 2e-30
gi|45552891|ref|NP_995972.1| CG16973-PC [Drosophila melanogaster... 137 2e-30
gi|25987447|gb|AAN75850.1| MAP4K3 [Homo sapiens] >gnl|BL_ORD_ID|... 137 2e-30
gi|15451902|ref|NP_003609.2| mitogen-activated protein kinase ki... 137 2e-30
gi|28509577|ref|XP_128800.3| mitogen-activated protein kinase ki... 137 2e-30
gi|34395226|dbj|BAC83750.1| putative MAP4 kinase [Oryza sativa (... 137 2e-30
gi|45549251|ref|NP_524679.3| CG16973-PA [Drosophila melanogaster... 137 2e-30
gi|6624079|gb|AAF19240.1|AC007684_1 germinal center kinase relat... 137 2e-30
gi|3095032|gb|AAC15472.1| germinal center kinase related protein... 137 2e-30
gi|31205899|ref|XP_311901.1| ENSANGP00000000236 [Anopheles gambi... 137 2e-30
gi|25405969|pir||C96572 protein F12M16.4 [imported] - Arabidopsi... 137 2e-30
gi|45199243|ref|NP_986272.1| AFR724Cp [Eremothecium gossypii] >g... 137 3e-30
gi|6822245|emb|CAB70978.1| p21 activated kinase 2 [Xenopus laevis] 136 4e-30
gi|34536821|ref|NP_899666.1| serine/threonine kinase 25 [Bos tau... 136 5e-30
gi|7510819|pir||T27623 hypothetical protein ZC504.4b - Caenorhab... 136 5e-30
gi|6226645|sp|Q23356|MI15_CAEEL Serine/threonine-protein kinase ... 136 5e-30
gi|24648046|ref|NP_732373.1| CG7717-PB [Drosophila melanogaster]... 135 6e-30
gi|15186734|dbj|BAB62891.1| mekk1a [Drosophila melanogaster] 135 6e-30
gi|17564378|ref|NP_505310.1| germinal Center Kinase (gck-1) [Cae... 135 6e-30
gi|15186736|dbj|BAB62892.1| mekk1b [Drosophila melanogaster] 135 6e-30
gi|24648048|ref|NP_650750.2| CG7717-PA [Drosophila melanogaster]... 135 6e-30
gi|22316558|emb|CAD44271.1| map 4 kinase alpha1 [Arabidopsis tha... 135 8e-30
gi|31215765|ref|XP_316092.1| ENSANGP00000005870 [Anopheles gambi... 135 8e-30
gi|50288881|ref|XP_446870.1| unnamed protein product [Candida gl... 135 8e-30
gi|6324459|ref|NP_014528.1| Serine/threonine protein kinase with... 135 8e-30
gi|50293717|ref|XP_449270.1| unnamed protein product [Candida gl... 135 1e-29
gi|3983166|gb|AAC95157.1| polo-like kinase kinase 1; xPlkk1 [Xen... 135 1e-29
gi|3114674|gb|AAC15972.1| kinase responsive to stress 1-like kin... 135 1e-29
gi|31201761|ref|XP_309828.1| ENSANGP00000018180 [Anopheles gambi... 135 1e-29
gi|31201845|ref|XP_309870.1| ENSANGP00000018246 [Anopheles gambi... 135 1e-29
gi|48097123|ref|XP_393691.1| similar to ENSANGP00000005870 [Apis... 135 1e-29
gi|47124946|gb|AAH70834.1| LOC431827 protein [Xenopus laevis] 135 1e-29
gi|19922606|ref|NP_611427.1| CG11228-PA [Drosophila melanogaster... 134 1e-29
gi|17564376|ref|NP_505309.1| germinal Center Kinase (gck-1) [Cae... 134 1e-29
gi|5138914|gb|AAD40374.1| PAK2 [Homo sapiens] 134 1e-29
gi|50256138|gb|EAL18865.1| hypothetical protein CNBI1260 [Crypto... 134 1e-29
gi|50727030|gb|AAT81184.1| Germinal center kinase family protein... 134 1e-29
gi|39595415|emb|CAE60453.1| Hypothetical protein CBG04061 [Caeno... 134 1e-29
gi|50291817|ref|XP_448341.1| unnamed protein product [Candida gl... 134 2e-29
gi|47271451|ref|NP_005981.2| serine/threonine kinase 10 [Homo sa... 134 2e-29
gi|38104690|gb|EAA51224.1| hypothetical protein MG08746.4 [Magna... 134 2e-29
gi|50551119|ref|XP_503033.1| hypothetical protein [Yarrowia lipo... 134 2e-29
gi|1518844|gb|AAC47308.1| p21-activated kinase CePAK [Caenorhabd... 134 2e-29
gi|83250|pir||S19488 probable membrane protein YCR073c - yeast (... 134 2e-29
gi|6321894|ref|NP_011970.1| Kinase that interacts with Cdc31p; N... 134 2e-29
gi|7495725|pir||T15467 hypothetical protein C09B8.7 - Caenorhabd... 134 2e-29
gi|172587|gb|AAA35039.1| STE20 134 2e-29
gi|6321780|ref|NP_011856.1| Signal transducing kinase of the PAK... 134 2e-29
gi|172586|gb|AAA35038.1| serine/threonine protein kinase 134 2e-29
gi|21362281|ref|NP_077237.1| mitogen-activated protein kinase ki... 134 2e-29
gi|28894837|gb|AAO61439.1| P21-activated kinase family protein 1... 134 2e-29
gi|32408943|ref|XP_324952.1| hypothetical protein [Neurospora cr... 134 2e-29
gi|25147913|ref|NP_741804.1| P21-Activated Kinase, colocalized w... 134 2e-29
gi|28894836|gb|AAO61438.1| P21-activated kinase family protein 1... 134 2e-29
gi|25147910|ref|NP_741803.1| P21-Activated Kinase, colocalized w... 134 2e-29
gi|6678163|ref|NP_033314.1| serine/threonine kinase 10 [Mus musc... 133 3e-29
gi|34328047|ref|NP_032305.1| mitogen activated protein kinase ki... 133 3e-29
gi|29427653|sp|P70218|M4K1_MOUSE Mitogen-activated protein kinas... 133 3e-29
gi|31981193|ref|NP_067512.2| serine/threonine kinase 25; Ste20-l... 133 3e-29
gi|45185584|ref|NP_983300.1| ACL104Cp [Eremothecium gossypii] >g... 133 3e-29
gi|25955505|gb|AAH40381.1| Map4k5 protein [Mus musculus] 133 4e-29
gi|24642565|ref|NP_523375.2| CG18582-PA [Drosophila melanogaster... 133 4e-29
gi|12643358|sp|O94804|STKA_HUMAN Serine/threonine-protein kinase... 133 4e-29
gi|39594475|emb|CAE72053.1| Hypothetical protein CBG19139 [Caeno... 133 4e-29
gi|33304017|gb|AAQ02516.1| serine/threonine kinase 10 [synthetic... 133 4e-29
gi|30315995|sp|Q8BPM2|M4K5_MOUSE Mitogen-activated protein kinas... 133 4e-29
gi|1129169|emb|CAA49163.1| protein kinase 75490 D [Saccharomyces... 133 4e-29
gi|871812|gb|AAA99196.1| ARA.KIN gene product 133 4e-29
gi|50749757|ref|XP_421743.1| PREDICTED: similar to hSLK [Gallus ... 133 4e-29
gi|48101223|ref|XP_392650.1| similar to CG7717-PB [Apis mellifera] 132 5e-29
gi|50415765|ref|XP_457495.1| unnamed protein product [Debaryomyc... 132 5e-29
gi|41462389|ref|NP_958927.1| mitogen-activated protein kinase ki... 132 5e-29
>gi|32563802|ref|NP_494925.2| neuronal SYmmetry defect NSY-1, Enhanced
Susceptibility to Pathogens ESP-8, ASK (MAPKKK) kinase
like (nsy-1) [Caenorhabditis elegans]
gi|28275136|gb|AAK31527.2| Neuronal symmetry protein 1
[Caenorhabditis elegans]
Length = 1425
Score = 2546 bits (6598), Expect = 0.0
Identities = 1287/1386 (92%), Positives = 1287/1386 (92%), Gaps = 18/1386 (1%)
Frame = +1
Query: 1 MSQNNKRQVQHNHEMSNDVCXXXXXXXXXXXXTAYHASRMAATSSSTNGSFEKSAIPGNA 180
MSQNNKRQVQHNHEMSNDVC TAYHASRMAATSSSTNGSFEKSAIPGNA
Sbjct: 1 MSQNNKRQVQHNHEMSNDVCPLPLPPRGAPPPTAYHASRMAATSSSTNGSFEKSAIPGNA 60
Query: 181 RKLHVVIVIDQKVQKNLRVREMALKDVQKVADTLNVNLTRIDFDKLDFGETETLDLFYNA 360
RKLHVVIVIDQKVQKNLRVREMALKDVQKVADTLNVNLTRIDFDKLDFGETETLDLFYNA
Sbjct: 61 RKLHVVIVIDQKVQKNLRVREMALKDVQKVADTLNVNLTRIDFDKLDFGETETLDLFYNA 120
Query: 361 DVALVDVTVTHQQPSLCYHIGVRESMGQSYNMILTYWSPDPEYHIMDALKKTHAHLPMIV 540
DVALVDVTVTHQQPSLCYHIGVRESMGQSYNMILTYWSPDPEYHIMDALKKTHAHLPMIV
Sbjct: 121 DVALVDVTVTHQQPSLCYHIGVRESMGQSYNMILTYWSPDPEYHIMDALKKTHAHLPMIV 180
Query: 541 YIHHQDSNQLQSYDKXXXXXXSKPPFARTNVPAKTITFQHRMKQVLKSVQVEASAHSREK 720
YIHHQDSNQLQSYDK SKPPFARTNVPAKTITFQHRMKQVLKSVQVEASAHSREK
Sbjct: 181 YIHHQDSNQLQSYDKNNNDDDSKPPFARTNVPAKTITFQHRMKQVLKSVQVEASAHSREK 240
Query: 721 FMSDLRKAREITDGDQKNDYLDKMRTRLDNPDVLHPDTVSLMMLSYRDNQNYGGMIRLVD 900
FMSDLRKAREITDGDQKNDYLDKMRTRLDNPDVLHPDTVSLMMLSYRDNQNYGGMIRLVD
Sbjct: 241 FMSDLRKAREITDGDQKNDYLDKMRTRLDNPDVLHPDTVSLMMLSYRDNQNYGGMIRLVD 300
Query: 901 DLKRIPDCLKVVDTPVIRYQYAFALNRRNKDGDRDLALNTVLSLVEGTTENEEKNGPLSP 1080
DLKRIPDCLKVVDTPVIRYQYAFALNRRNKDGDRDLALNTVLSLVEGTTENEEKNGPLSP
Sbjct: 301 DLKRIPDCLKVVDTPVIRYQYAFALNRRNKDGDRDLALNTVLSLVEGTTENEEKNGPLSP 360
Query: 1081 DVVCLAGRIYKDKFIASNYEDRESLNSAIEWYRRAFEMSPLEYSGINLTTLLRASGEHFE 1260
DVVCLAGRIYKDKFIASNYEDRESLNSAIEWYRRAFEMSPLEYSGINLTTLLRASGEHFE
Sbjct: 361 DVVCLAGRIYKDKFIASNYEDRESLNSAIEWYRRAFEMSPLEYSGINLTTLLRASGEHFE 420
Query: 1261 NNLEMQQIAVVLNSLLGRKGALQNLMEYWDVATYFEVSVLAENYQKACEAALMMVKLKPP 1440
NNLEMQQIAVVLNSLLGRKGALQNLMEYWDVATYFEVSVLAENYQKACEAALMMVKLKPP
Sbjct: 421 NNLEMQQIAVVLNSLLGRKGALQNLMEYWDVATYFEVSVLAENYQKACEAALMMVKLKPP 480
Query: 1441 VWYLKSTMENIKLINRCAATISPIEKEKQQFLFWSEFFMEATEADTDISCPRYPVLILEL 1620
VWYLKSTMENIKLINRCAATISPIEKEKQQFLFWSEFFMEATEADTDISCPRYPVLILEL
Sbjct: 481 VWYLKSTMENIKLINRCAATISPIEKEKQQFLFWSEFFMEATEADTDISCPRYPVLILEL 540
Query: 1621 NKEFTPSYLTLNNEEGTVILSHVLENSQQKKIHQSELRGIHRWHFARNNIKAVTESKRDD 1800
NKEFTPSYLTLNNEEGTVILSHVLENSQQKKIHQSELRGIHRWHFARNNIKAVTESKRDD
Sbjct: 541 NKEFTPSYLTLNNEEGTVILSHVLENSQQKKIHQSELRGIHRWHFARNNIKAVTESKRDD 600
Query: 1801 RQLFLYVHENSDDFNLLFPTKAHCKKAYDDMKSMADVADGNYQGRVLSNPDNEKIRFEYE 1980
RQLFLYVHENSDDFNLLFPTKAHCKKAYDDMKSMADVADGNYQGRVLSNPDNEKIRFEYE
Sbjct: 601 RQLFLYVHENSDDFNLLFPTKAHCKKAYDDMKSMADVADGNYQGRVLSNPDNEKIRFEYE 660
Query: 1981 LSNSNERVVLGKGTYGTVYAARDMDTQRQIVVKEIEVKYDEEVQPLMEEISLHSTLCHAN 2160
LSNSNERVVLGKGTYGTVYAARDMDTQRQIVVKEIEVKYDEEVQPLMEEISLHSTLCHAN
Sbjct: 661 LSNSNERVVLGKGTYGTVYAARDMDTQRQIVVKEIEVKYDEEVQPLMEEISLHSTLCHAN 720
Query: 2161 IVQYLGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLRSKWGPMNENAMNYYGKQILEGLKY 2340
IVQYLGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLRSKWGPMNENAMNYYGKQILEGLKY
Sbjct: 721 IVQYLGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLRSKWGPMNENAMNYYGKQILEGLKY 780
Query: 2341 LHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVTETFTGTLQYMAPEVIDH 2520
LHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVTETFTGTLQYMAPEVIDH
Sbjct: 781 LHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVTETFTGTLQYMAPEVIDH 840
Query: 2521 GQRGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQAAMFRVGMFKTHPPIPTEITEKCRN 2700
GQRGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQAAMFRVGMFKTHPPIPTEITEKCRN
Sbjct: 841 GQRGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQAAMFRVGMFKTHPPIPTEITEKCRN 900
Query: 2701 FIKSCFLPEACDRPSAKDLLQDPFIYHNHHSISRTRSGSINKKPATKIELNHDKEKKEKS 2880
FIKSCFLPEACDRPSAKDLLQDPFIYHNHHSISRTRSGSINKKPATKIELNHDKEKKEKS
Sbjct: 901 FIKSCFLPEACDRPSAKDLLQDPFIYHNHHSISRTRSGSINKKPATKIELNHDKEKKEKS 960
Query: 2881 KNQREMLRSTSHIGGMGVVERSPPTPEPMSATLTAGFSHVHSQTVSNALSTAREEKKLHL 3060
KNQREMLRSTSHIGGMGVVERSPPTPEPMSATLTAGFSHVHSQTVSNALSTAREEKKLHL
Sbjct: 961 KNQREMLRSTSHIGGMGVVERSPPTPEPMSATLTAGFSHVHSQTVSNALSTAREEKKLHL 1020
Query: 3061 KIDHARNRTFXXXXXXXXXXXXAGTNMSHPGFQLSQPSSPIVDDTNHPHLIVSPISLNTM 3240
KIDHARNRTF AGTNMSHPGFQLSQPSSPIVDDTNHPHLIVSPISLNTM
Sbjct: 1021 KIDHARNRTFSSSSPVPDGQSSAGTNMSHPGFQLSQPSSPIVDDTNHPHLIVSPISLNTM 1080
Query: 3241 GSPLSSAALLNRTIXXXXXXXXXRFFMLQKDSERRRSLGQFMQDYKDLIIDSWSTLLIKQ 3420
GSPLSSAALLNRTI RFFMLQKDSERRRSLGQFMQDYKDLIIDSWSTLLIKQ
Sbjct: 1081 GSPLSSAALLNRTISDESSNSSSRFFMLQKDSERRRSLGQFMQDYKDLIIDSWSTLLIKQ 1140
Query: 3421 SDTELVVTVYMLEMLLDGMRDFLLKKDNTKMQKMIDDIRGLLDYDTAKIGQINLALYHFS 3600
SDTELVVTVYMLEMLLDGMRDFLLKKDNTKMQKMIDDIRGLLDYDTAKIGQINLALYHFS
Sbjct: 1141 SDTELVVTVYMLEMLLDGMRDFLLKKDNTKMQKMIDDIRGLLDYDTAKIGQINLALYHFS 1200
Query: 3601 DSIQPVLRRLDIKPHWMFALSNLITSAVQCAXXXXXXXXXXXXHAQDNLPSTSSIVAIRN 3780
DSIQPVLRRLDIKPHWMFALSNLITSAVQCA HAQDNLPSTSSIVAIRN
Sbjct: 1201 DSIQPVLRRLDIKPHWMFALSNLITSAVQCAISILSPDLSLLLHAQDNLPSTSSIVAIRN 1260
Query: 3781 SSLSEGEALIXXXXXXXXXXXXXDRKELRTXX------------------XXXXXXXXXX 3906
SSLSEGEALI DRKELRT
Sbjct: 1261 SSLSEGEALIESRPPSREERVREDRKELRTLQEENEILIERLLQKIIMPPGTENNYQVTR 1320
Query: 3907 XXXXXVSWLRGLEIDERSIALIASEAYTKSDMMDFVTRDELLSIGVGGGSSCRIMRAIGE 4086
VSWLRGLEIDERSIALIASEAYTKSDMMDFVTRDELLSIGVGGGSSCRIMRAIGE
Sbjct: 1321 VQEELVSWLRGLEIDERSIALIASEAYTKSDMMDFVTRDELLSIGVGGGSSCRIMRAIGE 1380
Query: 4087 VRERQR 4104
VRERQR
Sbjct: 1381 VRERQR 1386
>gi|7504728|pir||T16511 hypothetical protein F59A6.1 - Caenorhabditis
elegans
Length = 1387
Score = 2446 bits (6340), Expect = 0.0
Identities = 1226/1290 (95%), Positives = 1226/1290 (95%)
Frame = +1
Query: 1 MSQNNKRQVQHNHEMSNDVCXXXXXXXXXXXXTAYHASRMAATSSSTNGSFEKSAIPGNA 180
MSQNNKRQVQHNHEMSNDVC TAYHASRMAATSSSTNGSFEKSAIPGNA
Sbjct: 1 MSQNNKRQVQHNHEMSNDVCPLPLPPRGAPPPTAYHASRMAATSSSTNGSFEKSAIPGNA 60
Query: 181 RKLHVVIVIDQKVQKNLRVREMALKDVQKVADTLNVNLTRIDFDKLDFGETETLDLFYNA 360
RKLHVVIVIDQKVQKNLRVREMALKDVQKVADTLNVNLTRIDFDKLDFGETETLDLFYNA
Sbjct: 61 RKLHVVIVIDQKVQKNLRVREMALKDVQKVADTLNVNLTRIDFDKLDFGETETLDLFYNA 120
Query: 361 DVALVDVTVTHQQPSLCYHIGVRESMGQSYNMILTYWSPDPEYHIMDALKKTHAHLPMIV 540
DVALVDVTVTHQQPSLCYHIGVRESMGQSYNMILTYWSPDPEYHIMDALKKTHAHLPMIV
Sbjct: 121 DVALVDVTVTHQQPSLCYHIGVRESMGQSYNMILTYWSPDPEYHIMDALKKTHAHLPMIV 180
Query: 541 YIHHQDSNQLQSYDKXXXXXXSKPPFARTNVPAKTITFQHRMKQVLKSVQVEASAHSREK 720
YIHHQDSNQLQSYDK SKPPFARTNVPAKTITFQHRMKQVLKSVQVEASAHSREK
Sbjct: 181 YIHHQDSNQLQSYDKNNNDDDSKPPFARTNVPAKTITFQHRMKQVLKSVQVEASAHSREK 240
Query: 721 FMSDLRKAREITDGDQKNDYLDKMRTRLDNPDVLHPDTVSLMMLSYRDNQNYGGMIRLVD 900
FMSDLRKAREITDGDQKNDYLDKMRTRLDNPDVLHPDTVSLMMLSYRDNQNYGGMIRLVD
Sbjct: 241 FMSDLRKAREITDGDQKNDYLDKMRTRLDNPDVLHPDTVSLMMLSYRDNQNYGGMIRLVD 300
Query: 901 DLKRIPDCLKVVDTPVIRYQYAFALNRRNKDGDRDLALNTVLSLVEGTTENEEKNGPLSP 1080
DLKRIPDCLKVVDTPVIRYQYAFALNRRNKDGDRDLALNTVLSLVEGTTENEEKNGPLSP
Sbjct: 301 DLKRIPDCLKVVDTPVIRYQYAFALNRRNKDGDRDLALNTVLSLVEGTTENEEKNGPLSP 360
Query: 1081 DVVCLAGRIYKDKFIASNYEDRESLNSAIEWYRRAFEMSPLEYSGINLTTLLRASGEHFE 1260
DVVCLAGRIYKDKFIASNYEDRESLNSAIEWYRRAFEMSPLEYSGINLTTLLRASGEHFE
Sbjct: 361 DVVCLAGRIYKDKFIASNYEDRESLNSAIEWYRRAFEMSPLEYSGINLTTLLRASGEHFE 420
Query: 1261 NNLEMQQIAVVLNSLLGRKGALQNLMEYWDVATYFEVSVLAENYQKACEAALMMVKLKPP 1440
NNLEMQQIAVVLNSLLGRKGALQNLMEYWDVATYFEVSVLAENYQKACEAALMMVKLKPP
Sbjct: 421 NNLEMQQIAVVLNSLLGRKGALQNLMEYWDVATYFEVSVLAENYQKACEAALMMVKLKPP 480
Query: 1441 VWYLKSTMENIKLINRCAATISPIEKEKQQFLFWSEFFMEATEADTDISCPRYPVLILEL 1620
VWYLKSTMENIKLINRCAATISPIEKEKQQFLFWSEFFMEATEADTDISCPRYPVLILEL
Sbjct: 481 VWYLKSTMENIKLINRCAATISPIEKEKQQFLFWSEFFMEATEADTDISCPRYPVLILEL 540
Query: 1621 NKEFTPSYLTLNNEEGTVILSHVLENSQQKKIHQSELRGIHRWHFARNNIKAVTESKRDD 1800
NKEFTPSYLTLNNEEGTVILSHVLENSQQKKIHQSELRGIHRWHFARNNIKAVTESKRDD
Sbjct: 541 NKEFTPSYLTLNNEEGTVILSHVLENSQQKKIHQSELRGIHRWHFARNNIKAVTESKRDD 600
Query: 1801 RQLFLYVHENSDDFNLLFPTKAHCKKAYDDMKSMADVADGNYQGRVLSNPDNEKIRFEYE 1980
RQLFLYVHENSDDFNLLFPTKAHCKKAYDDMKSMADVADGNYQGRVLSNPDNEKIRFEYE
Sbjct: 601 RQLFLYVHENSDDFNLLFPTKAHCKKAYDDMKSMADVADGNYQGRVLSNPDNEKIRFEYE 660
Query: 1981 LSNSNERVVLGKGTYGTVYAARDMDTQRQIVVKEIEVKYDEEVQPLMEEISLHSTLCHAN 2160
LSNSNERVVLGKGTYGTVYAARDMDTQRQIVVKEIEVKYDEEVQPLMEEISLHSTLCHAN
Sbjct: 661 LSNSNERVVLGKGTYGTVYAARDMDTQRQIVVKEIEVKYDEEVQPLMEEISLHSTLCHAN 720
Query: 2161 IVQYLGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLRSKWGPMNENAMNYYGKQILEGLKY 2340
IVQYLGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLRSKWGPMNENAMNYYGKQILEGLKY
Sbjct: 721 IVQYLGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLRSKWGPMNENAMNYYGKQILEGLKY 780
Query: 2341 LHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVTETFTGTLQYMAPEVIDH 2520
LHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVTETFTGTLQYMAPEVIDH
Sbjct: 781 LHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVTETFTGTLQYMAPEVIDH 840
Query: 2521 GQRGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQAAMFRVGMFKTHPPIPTEITEKCRN 2700
GQRGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQAAMFRVGMFKTHPPIPTEITEKCRN
Sbjct: 841 GQRGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQAAMFRVGMFKTHPPIPTEITEKCRN 900
Query: 2701 FIKSCFLPEACDRPSAKDLLQDPFIYHNHHSISRTRSGSINKKPATKIELNHDKEKKEKS 2880
FIKSCFLPEACDRPSAKDLLQDPFIYHNHHSISRTRSGSINKKPATKIELNHDKEKKEKS
Sbjct: 901 FIKSCFLPEACDRPSAKDLLQDPFIYHNHHSISRTRSGSINKKPATKIELNHDKEKKEKS 960
Query: 2881 KNQREMLRSTSHIGGMGVVERSPPTPEPMSATLTAGFSHVHSQTVSNALSTAREEKKLHL 3060
KNQREMLRSTSHIGGMGVVERSPPTPEPMSATLTAGFSHVHSQTVSNALSTAREEKKLHL
Sbjct: 961 KNQREMLRSTSHIGGMGVVERSPPTPEPMSATLTAGFSHVHSQTVSNALSTAREEKKLHL 1020
Query: 3061 KIDHARNRTFXXXXXXXXXXXXAGTNMSHPGFQLSQPSSPIVDDTNHPHLIVSPISLNTM 3240
KIDHARNRTF AGTNMSHPGFQLSQPSSPIVDDTNHPHLIVSPISLNTM
Sbjct: 1021 KIDHARNRTFSSSSPVPDGQSSAGTNMSHPGFQLSQPSSPIVDDTNHPHLIVSPISLNTM 1080
Query: 3241 GSPLSSAALLNRTIXXXXXXXXXRFFMLQKDSERRRSLGQFMQDYKDLIIDSWSTLLIKQ 3420
GSPLSSAALLNRTI RFFMLQKDSERRRSLGQFMQDYKDLIIDSWSTLLIKQ
Sbjct: 1081 GSPLSSAALLNRTISDESSNSSSRFFMLQKDSERRRSLGQFMQDYKDLIIDSWSTLLIKQ 1140
Query: 3421 SDTELVVTVYMLEMLLDGMRDFLLKKDNTKMQKMIDDIRGLLDYDTAKIGQINLALYHFS 3600
SDTELVVTVYMLEMLLDGMRDFLLKKDNTKMQKMIDDIRGLLDYDTAKIGQINLALYHFS
Sbjct: 1141 SDTELVVTVYMLEMLLDGMRDFLLKKDNTKMQKMIDDIRGLLDYDTAKIGQINLALYHFS 1200
Query: 3601 DSIQPVLRRLDIKPHWMFALSNLITSAVQCAXXXXXXXXXXXXHAQDNLPSTSSIVAIRN 3780
DSIQPVLRRLDIKPHWMFALSNLITSAVQCA HAQDNLPSTSSIVAIRN
Sbjct: 1201 DSIQPVLRRLDIKPHWMFALSNLITSAVQCAISILSPDLSLLLHAQDNLPSTSSIVAIRN 1260
Query: 3781 SSLSEGEALIXXXXXXXXXXXXXDRKELRT 3870
SSLSEGEALI DRKELRT
Sbjct: 1261 SSLSEGEALIESRPPSREERVREDRKELRT 1290
>gi|39596795|emb|CAE59022.1| Hypothetical protein CBG02299
[Caenorhabditis briggsae]
Length = 1364
Score = 2307 bits (5979), Expect = 0.0
Identities = 1165/1369 (85%), Positives = 1220/1369 (89%), Gaps = 1/1369 (0%)
Frame = +1
Query: 1 MSQNNKRQVQHNHEMSNDVCXXXXXXXXXXXXTAYHASRMAATSSSTNGSFEKSAIPGNA 180
MSQNNK+QV H+ ++SNDVC T YH +RMA T S TNGSF+K+ IPGNA
Sbjct: 1 MSQNNKKQV-HHPDISNDVCPLPLPPRGAPPPTVYHTTRMAPTPS-TNGSFDKTVIPGNA 58
Query: 181 RKLHVVIVIDQKVQKNLRVREMALKDVQKVADTLNVNLTRIDFDKLDFGETETLDLFYNA 360
RKLHVVIVIDQKVQKNLRVREMALKDVQKVADTLNVNL +IDFDKLDFGETETLDLFYNA
Sbjct: 59 RKLHVVIVIDQKVQKNLRVREMALKDVQKVADTLNVNLAKIDFDKLDFGETETLDLFYNA 118
Query: 361 DVALVDVTVTHQQPSLCYHIGVRESMGQSYNMILTYWSPDPEYHIMDALKKTHAHLPMIV 540
DVALVDVTVTHQQPSLCYHIGVRESMGQSYNMILTY +PD EYHIMDALKKTHAHLPMI+
Sbjct: 119 DVALVDVTVTHQQPSLCYHIGVRESMGQSYNMILTYLAPDLEYHIMDALKKTHAHLPMII 178
Query: 541 YIHHQDSNQLQSYDKXXXXXXSKPPFARTN-VPAKTITFQHRMKQVLKSVQVEASAHSRE 717
YI+ + LQSY+K +KPPFAR N AK TFQ+R+K VLKSVQVEASAHSRE
Sbjct: 179 YINSPECGMLQSYEKNGNEDDAKPPFARANSTTAKMTTFQNRLKSVLKSVQVEASAHSRE 238
Query: 718 KFMSDLRKAREITDGDQKNDYLDKMRTRLDNPDVLHPDTVSLMMLSYRDNQNYGGMIRLV 897
KFMSDLRKAREITDGDQKND+LDKMRTRLDNPDVLHPDTVSLMMLSYRDNQNYGGMIRLV
Sbjct: 239 KFMSDLRKAREITDGDQKNDFLDKMRTRLDNPDVLHPDTVSLMMLSYRDNQNYGGMIRLV 298
Query: 898 DDLKRIPDCLKVVDTPVIRYQYAFALNRRNKDGDRDLALNTVLSLVEGTTENEEKNGPLS 1077
DDLKRI DC+KVVDTPVIRYQYAFALNRRNK GDRDLALNTVLSL+ GTTENEEKNG LS
Sbjct: 299 DDLKRITDCVKVVDTPVIRYQYAFALNRRNKGGDRDLALNTVLSLIGGTTENEEKNGLLS 358
Query: 1078 PDVVCLAGRIYKDKFIASNYEDRESLNSAIEWYRRAFEMSPLEYSGINLTTLLRASGEHF 1257
PDVVCLAGRIYKDKFIASNYEDR+SLNSAIEWYR+AFEMSPLEYSGINLTTLLRASGEHF
Sbjct: 359 PDVVCLAGRIYKDKFIASNYEDRDSLNSAIEWYRKAFEMSPLEYSGINLTTLLRASGEHF 418
Query: 1258 ENNLEMQQIAVVLNSLLGRKGALQNLMEYWDVATYFEVSVLAENYQKACEAALMMVKLKP 1437
ENNLEMQQIAVVLNSLLGRKGALQNL EYWDVATYFEVSVLAENYQKACEAALMMVKLKP
Sbjct: 419 ENNLEMQQIAVVLNSLLGRKGALQNLTEYWDVATYFEVSVLAENYQKACEAALMMVKLKP 478
Query: 1438 PVWYLKSTMENIKLINRCAATISPIEKEKQQFLFWSEFFMEATEADTDISCPRYPVLILE 1617
PVWYLKSTMENIKLINRCAAT+SPIEKEKQQFLFWSEFFMEATE DTDI+CPRYPVLILE
Sbjct: 479 PVWYLKSTMENIKLINRCAATVSPIEKEKQQFLFWSEFFMEATETDTDINCPRYPVLILE 538
Query: 1618 LNKEFTPSYLTLNNEEGTVILSHVLENSQQKKIHQSELRGIHRWHFARNNIKAVTESKRD 1797
L KEFTPSYLTLN EEGTVILSHVLE SQQKKIHQSE++GIHRWHF R NIKAVTESKRD
Sbjct: 539 LTKEFTPSYLTLNTEEGTVILSHVLETSQQKKIHQSEVKGIHRWHFTRTNIKAVTESKRD 598
Query: 1798 DRQLFLYVHENSDDFNLLFPTKAHCKKAYDDMKSMADVADGNYQGRVLSNPDNEKIRFEY 1977
DRQLFLYVHENSDDFNLLFPTKAHC+KA+DDMKSMADV DGNYQG+VLSNPDNEKIRFEY
Sbjct: 599 DRQLFLYVHENSDDFNLLFPTKAHCQKAFDDMKSMADVEDGNYQGKVLSNPDNEKIRFEY 658
Query: 1978 ELSNSNERVVLGKGTYGTVYAARDMDTQRQIVVKEIEVKYDEEVQPLMEEISLHSTLCHA 2157
EL+NSNERVVLGKGTYGTVY+ARDMDTQRQIVVKE+EVKYDEEVQPLMEEI LHSTL H
Sbjct: 659 ELNNSNERVVLGKGTYGTVYSARDMDTQRQIVVKEVEVKYDEEVQPLMEEIGLHSTLSHQ 718
Query: 2158 NIVQYLGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLRSKWGPMNENAMNYYGKQILEGLK 2337
NIVQYLGCDLVG++GSND FLIFMEHVPGGSLSSLLRSKWG ++E M YYGKQILEGLK
Sbjct: 719 NIVQYLGCDLVGREGSNDTFLIFMEHVPGGSLSSLLRSKWGSVSEQNMVYYGKQILEGLK 778
Query: 2338 YLHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVTETFTGTLQYMAPEVID 2517
YLHE KIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVTETFTGTLQYMAPEVID
Sbjct: 779 YLHEQKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVTETFTGTLQYMAPEVID 838
Query: 2518 HGQRGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQAAMFRVGMFKTHPPIPTEITEKCR 2697
HGQRGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQAAMFRVGMFKTHPPIP E+TEKCR
Sbjct: 839 HGQRGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQAAMFRVGMFKTHPPIPAELTEKCR 898
Query: 2698 NFIKSCFLPEACDRPSAKDLLQDPFIYHNHHSISRTRSGSINKKPATKIELNHDKEKKEK 2877
NFIK CFLPEACDRPSAKDLLQDPF+ HHSISRTRSGSINKKP KIEL DKEKKEK
Sbjct: 899 NFIKRCFLPEACDRPSAKDLLQDPFM---HHSISRTRSGSINKKPLKKIELKQDKEKKEK 955
Query: 2878 SKNQREMLRSTSHIGGMGVVERSPPTPEPMSATLTAGFSHVHSQTVSNALSTAREEKKLH 3057
SKNQREMLRSTSHIGGMGV+ERSPPTPEP SATLTAGFSH HSQTVSNALS AREEKKLH
Sbjct: 956 SKNQREMLRSTSHIGGMGVIERSPPTPEPTSATLTAGFSHAHSQTVSNALSIAREEKKLH 1015
Query: 3058 LKIDHARNRTFXXXXXXXXXXXXAGTNMSHPGFQLSQPSSPIVDDTNHPHLIVSPISLNT 3237
LKIDHARNRTF AGTNMSHPGF LSQPSSPIVDDT +P LIVSP++L+T
Sbjct: 1016 LKIDHARNRTFSSSSPVPDGQSSAGTNMSHPGFHLSQPSSPIVDDTTYPQLIVSPVTLST 1075
Query: 3238 MGSPLSSAALLNRTIXXXXXXXXXRFFMLQKDSERRRSLGQFMQDYKDLIIDSWSTLLIK 3417
+GSPLSSAALLNRTI RFFMLQKDSERRRSLGQFM DYKDLIIDSWSTLLI+
Sbjct: 1076 LGSPLSSAALLNRTISDESSNSSSRFFMLQKDSERRRSLGQFMTDYKDLIIDSWSTLLIQ 1135
Query: 3418 QSDTELVVTVYMLEMLLDGMRDFLLKKDNTKMQKMIDDIRGLLDYDTAKIGQINLALYHF 3597
QSDTELVVTV MLEMLL+GMRDFLLKKDN KMQ+ IDDIRGLLDYDTAKI QINLALYHF
Sbjct: 1136 QSDTELVVTVCMLEMLLEGMRDFLLKKDNAKMQEKIDDIRGLLDYDTAKIAQINLALYHF 1195
Query: 3598 SDSIQPVLRRLDIKPHWMFALSNLITSAVQCAXXXXXXXXXXXXHAQDNLPSTSSIVAIR 3777
SDSIQPVLRRLDIKPHWMFALSNLITSAVQ A HAQDNLP+TSSI A+R
Sbjct: 1196 SDSIQPVLRRLDIKPHWMFALSNLITSAVQNAISILSPDLSLLLHAQDNLPTTSSIAAVR 1255
Query: 3778 NSSLSEGEALIXXXXXXXXXXXXXDRKELRTXXXXXXXXXXXXXXXXXVSWLRGLEIDER 3957
NSSLSEGEALI DRKELRT V+WLRGLEIDER
Sbjct: 1256 NSSLSEGEALIESRPPSREERVKEDRKELRTLQEENELLIEKLLQEELVNWLRGLEIDER 1315
Query: 3958 SIALIASEAYTKSDMMDFVTRDELLSIGVGGGSSCRIMRAIGEVRERQR 4104
S ALIASEAYTK+D++DFVTRDELL+IG+GGG SCRIMRAIGE+RERQR
Sbjct: 1316 STALIASEAYTKNDLIDFVTRDELLNIGIGGGPSCRIMRAIGEIRERQR 1364
>gi|48098524|ref|XP_392079.1| similar to CG4720-PA [Apis mellifera]
Length = 1737
Score = 803 bits (2074), Expect = 0.0
Identities = 441/899 (49%), Positives = 600/899 (66%), Gaps = 18/899 (2%)
Frame = +1
Query: 133 SSTNGSFEKSAIPGNAR-----KLHVVIVIDQKVQKNLRVREMALKDVQKVADTLNVNLT 297
SST+ S I G+ ++ V V+D + ++L R AL++V++ + +N N+
Sbjct: 273 SSTDSIGTHSDISGHTTISGRPRMDVACVLDLQQPEHLAQRRRALEEVRQACNLVNANIH 332
Query: 298 RIDFDKLDFGETETLDLFYNADVALVDVTVTHQQPSLCYHIGVRESMGQSYNMILTYWSP 477
I F+KLDFGET LD FYNADVA+VD+++ QQ +L YH+GVRES G N++L
Sbjct: 333 HIQFEKLDFGETNVLDTFYNADVAVVDLSIQLQQSALFYHLGVRESFGMKENILL---HN 389
Query: 478 DPEYHIMDALKKTHAHLPMIVYIHHQDSNQLQSYDKXXXXXXSKPPFARTNVPAKTITFQ 657
D + +K + + + Y + + P R Q
Sbjct: 390 DIDTETTIRIKLSCGNYTFVSY----------RVVECGSCVATNPATTRITGEEVIDPKQ 439
Query: 658 H---RMKQVLKSVQVEASAHSREKFMSDLRKAREITDGDQKNDYLDKMRTRLDNPDVLHP 828
H ++K++ + V+V++ AH +EKF++DLRKARE G++ + L+ MR RLD+P+VL
Sbjct: 440 HLTLKLKKLFQDVEVQSKAHMKEKFLADLRKARETYSGEELSKALNNMRKRLDDPNVLSG 499
Query: 829 DTVSLMMLSYRDNQNYGGMIRLVDDLKRIPDCLKVVDTPVIRYQYAFALNRRNKDGDRDL 1008
+ V +++S+R+ Q+Y M++LVDDL+ IP ++TP IR YAFALNRRNK+GDR+
Sbjct: 500 EVVLNVLISFREIQDYDAMVQLVDDLRTIPTHKNYINTPAIRNLYAFALNRRNKEGDRER 559
Query: 1009 ALNTVLSLVEGTTENEEKNGPLSPDVVCLAGRIYKDKFIASNYEDRESLNSAIEWYRRAF 1188
AL ++E E +E + PD++CL GRIYKDKF+ S + D+ESL +AI WYR+ F
Sbjct: 560 ALK----VIEKALEKKENH---VPDMLCLCGRIYKDKFVESRHTDKESLKNAIHWYRKGF 612
Query: 1189 EMSPLEYSGINLTTLLRASGEHFENNLEMQQIAVVLNSLLGRKGALQNLMEYWDVATYFE 1368
E+ P EY+GINL TLL +G F + E+Q I +VLN+L+G+KG+L +L +YWDVAT+FE
Sbjct: 613 EVQPNEYAGINLATLLVIAGNEFSKSEELQHIGMVLNNLIGKKGSLSSLKDYWDVATFFE 672
Query: 1369 VSVLAENYQKACEAALMMVKLKPPVWYLKSTMENIKLINRCA-----ATISPIEKEKQQF 1533
+SVLAE+Y KA +AA M KLKPP WYLKST+ NI LI+R A +SP E+Q F
Sbjct: 673 ISVLAEDYSKAIQAAECMFKLKPPNWYLKSTIGNISLIDRFRKKNEEAEVSP---EEQIF 729
Query: 1534 LFWSEFFMEATEADTDISCPRYPVLILELNKEFTPSYLTLN---NEEGTVILSHVLENSQ 1704
FW+++F EAT+A+ S R+P+L+LE K PSY+ +N E+ I + L+N +
Sbjct: 730 SFWTDYFAEATKAEVGDSI-RFPLLVLEPTKILMPSYVNVNLGAEEKSVQIWNLCLDNMK 788
Query: 1705 QKKIHQSELRGIHRWHFARNNIKAVTESKRDDRQLFLYVHENSDDFNLLFPTKAHCKKAY 1884
+ + +H W F N I++V+ KRD+R LFLYVH+NSDDF + FP+ ++ Y
Sbjct: 789 ------NNCKQVHDWLFTANMIRSVSLYKRDERCLFLYVHQNSDDFQMYFPSVQCRQRFY 842
Query: 1885 DDMKSMADVADGNYQGRVLSNPDNEKIRFEYELSNSNERVVLGKGTYGTVYAARDMDTQR 2064
D + M +G D ++++FEYEL + N+R++LGKGTYG VYAARD++TQ
Sbjct: 843 DLILEMTRDQEGMVTDLDAYMTD-DRMKFEYELDDQNKRIMLGKGTYGIVYAARDLNTQV 901
Query: 2065 QIVVKEIEVKYDEEVQPLMEEISLHSTLCHANIVQYLGCDLVGKDGSNDHFLIFMEHVPG 2244
+I VKEI + +VQPL EEI LHS L H NIVQYLG V ++G +F IFME VPG
Sbjct: 902 RIAVKEIRERNLGDVQPLHEEIKLHSQLRHRNIVQYLGS--VSEEG---YFKIFMEQVPG 956
Query: 2245 GSLSSLLRSKWGPM--NENAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLVNTYSGVCK 2418
GSLS+LLRSKWGP+ NE+ + YY KQILEGLKYLH+ KIVHRDIKGDNVLVNTYSGV K
Sbjct: 957 GSLSALLRSKWGPLKENESTIAYYTKQILEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVK 1016
Query: 2419 ISDFGTCKRLAGLNPVTETFTGTLQYMAPEVIDHGQRGYGAPADIWSFGCTMVEMATGRP 2598
ISDFG KRLAGL P TETFTGTLQYMAPEVID GQRGYGAPADIWS GCT+VEMATG+P
Sbjct: 1017 ISDFGMSKRLAGLCPSTETFTGTLQYMAPEVIDKGQRGYGAPADIWSLGCTIVEMATGKP 1076
Query: 2599 PFVEMQNPQAAMFRVGMFKTHPPIPTEITEKCRNFIKSCFLPEACDRPSAKDLLQDPFI 2775
PF+E+ +PQAA+F+VG +K HP IP+E++E+ +NFI CF P R +A +LL+DPF+
Sbjct: 1077 PFIELGSPQAAVFKVGYYKIHPEIPSELSERAKNFILRCFEPNPDIRATAAELLEDPFL 1135
Score = 87.0 bits (214), Expect = 3e-15
Identities = 45/128 (35%), Positives = 79/128 (61%), Gaps = 1/128 (0%)
Frame = +1
Query: 3313 FFMLQKDSERRRSLGQFMQDYKDLIIDSWST-LLIKQSDTELVVTVYMLEMLLDGMRDFL 3489
F++L+KDS+RR +L + + + I + W + I+ S ++ V+ + L +L+ +RD++
Sbjct: 1240 FYLLKKDSQRRMTLTRVLTQDEAKICEVWMRDIQIELSTSQTVLQMNHLILLMRALRDYI 1299
Query: 3490 LKKDNTKMQKMIDDIRGLLDYDTAKIGQINLALYHFSDSIQPVLRRLDIKPHWMFALSNL 3669
+++ + I ++ LD+D+ I +NLA+Y F ++ VLR IKPHWMFAL NL
Sbjct: 1300 AEQNQEVIVTAIRTLKEELDFDSTAITHLNLAIYLFQTAVNEVLRMHSIKPHWMFALDNL 1359
Query: 3670 ITSAVQCA 3693
+ +AVQ A
Sbjct: 1360 VRNAVQAA 1367
Score = 45.1 bits (105), Expect = 0.015
Identities = 21/58 (36%), Positives = 35/58 (60%)
Frame = +1
Query: 3922 VSWLRGLEIDERSIALIASEAYTKSDMMDFVTRDELLSIGVGGGSSCRIMRAIGEVRE 4095
+ WL+ L+ID+ +I E YT D+++ VTRD++ + GG RI +AI + R+
Sbjct: 1516 IEWLQNLQIDDMTIERFLYEQYTLEDILNHVTRDDIRRLNFRGGIELRIWQAILKHRQ 1573
>gi|23237772|dbj|BAC16514.1| DASK1 [Drosophila melanogaster]
Length = 1367
Score = 793 bits (2049), Expect = 0.0
Identities = 438/876 (50%), Positives = 573/876 (65%), Gaps = 13/876 (1%)
Frame = +1
Query: 187 LHVVIVIDQKVQKNLRVREMALKDVQKVADTLNVNLTRIDFDKLDFGETETLDLFYNADV 366
+ VV V+D V +L R+ AL+++++ + N R+ F++LDFGET L+ FYNADV
Sbjct: 5 MDVVCVMDTAVGDHLEDRQCALEEIKQAVQSAGANFQRVQFERLDFGETNVLETFYNADV 64
Query: 367 ALVDVTVTHQQPSLCYHIGVRESMGQSYNMILTYWSPDPEYHIMDALKKTHAHLPMIVYI 546
A++D+++ QQ L YH GVRES G N ILTY D + + +LK + A+ + Y
Sbjct: 65 AIIDLSILTQQRPLSYHYGVRESFGMKEN-ILTYNDIDSKQTL--SLKLSCANYLFLSYK 121
Query: 547 HHQDSNQLQSYDKXXXXXXSKPPFARTNVPAKTITFQHRMKQVLKSVQVEASAHSREKFM 726
+ ++N + SK P A VP T Q R+K+ L+ V++++ AH REKF+
Sbjct: 122 RNAETNSCHLTSQPNSGNNSKEPNAEGRVP----TLQWRLKRKLQDVEIQSKAHMREKFL 177
Query: 727 SDLRKAREI--TDGDQKNDYLDKMRTRLDNPDVLHPDTVSLMMLSYRDNQNYGGMIRLVD 900
SD+R AR+ T+G + L +MR RLD+P VL + V M S RD Q+Y M+RLV+
Sbjct: 178 SDMRTARDTYATNGAKLQSILHEMRKRLDDPHVLSGEVVHSFMCSLRDVQDYDAMVRLVN 237
Query: 901 DLKRIPDCLKVVDTPVIRYQYAFALNRRNKDGDRDLALNTVLSLVEGTTENEEKNGPLSP 1080
DLK IP+ K V+T + + YAFALNRRN+ GDR+ AL + L +E K P
Sbjct: 238 DLKNIPNTRKYVETGNMSFLYAFALNRRNRKGDREKALESSLKALE-------KKENHFP 290
Query: 1081 DVVCLAGRIYKDKFIASNYEDRESLNSAIEWYRRAFEMSPLEYSGINLTTLLRASGEHFE 1260
D++CL GRIYKD F+ S+Y D SL AI+WYR++FE+ P EY+GINL TLL G+ F
Sbjct: 291 DMLCLCGRIYKDIFVESDYTDATSLAHAIKWYRQSFEVQPNEYAGINLATLLVIEGKEFT 350
Query: 1261 NNLEMQQIAVVLNSLLGRKGALQNLMEYWDVATYFEVSVLAENYQKACEAALMMVKLKPP 1440
N E+Q I + LN+L+G+KG+L +L EYWDVAT+FE+SVLA +Y KA +AA M KLKPP
Sbjct: 351 NTEELQHIGMTLNNLIGKKGSLSSLSEYWDVATFFEISVLANDYAKAIQAAECMFKLKPP 410
Query: 1441 VWYLKSTMENIKLINRCAATISPIEK----EKQQFLFWSEFFMEATEADTDISCPRYPVL 1608
WYLKST+ NI LI+R P E+ E+Q F FW +FF+EAT + + R+P+L
Sbjct: 411 NWYLKSTIGNISLIHRFRK--KPEERQPPIEEQVFQFWMDFFLEATNTEEVKNSIRFPIL 468
Query: 1609 ILELNKEFTPSYLTLN---NEEGTVILSHVLENSQQKKIHQSELRGIHRWHFARNNIKAV 1779
ILE K + PSY+T+N +E+ I++ L +++ + + IH + F + IK+V
Sbjct: 469 ILEPQKIYMPSYVTINMDADEKSIQIVNICLAHAK------NACKKIHDFLFVASKIKSV 522
Query: 1780 TESKRDDRQLFLYVHENSDDFNLLFPTKAHCKKAYDDMKSMA--DVADGNYQGRVLSNPD 1953
+ KRDDR +LYVH NSDDF + FP+ +K YD + M V N LSN D
Sbjct: 523 SLYKRDDRCAYLYVHHNSDDFQIYFPSTERRQKFYDMILEMTADQVVFVN-----LSN-D 576
Query: 1954 NEKIRFEYELSNSNERVVLGKGTYGTVYAARDMDTQRQIVVKEIEVKYDEEVQPLMEEIS 2133
+ I +EY+ N ++VLGKGTYGTVYAARD TQ +I +KE+ K ++VQPL EEI
Sbjct: 577 DANIEYEYDYDEQNRKMVLGKGTYGTVYAARDKQTQVRIAIKEVPEKNSQDVQPLHEEIK 636
Query: 2134 LHSTLCHANIVQYLGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLRSKWGPM--NENAMNY 2307
LHS L H NIV+YLG N F IFME VPGGSLS LL +KWGP+ NE+ M +
Sbjct: 637 LHSQLRHRNIVRYLG-----SCSENGFFKIFMEQVPGGSLSDLLETKWGPLKDNESTMAF 691
Query: 2308 YGKQILEGLKYLHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVTETFTGT 2487
Y KQILEGLKYLHE IVHRDIKGDNVLVNTYSGV KISDFGT KRLA +NP+TETFTGT
Sbjct: 692 YSKQILEGLKYLHEQDIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLARINPMTETFTGT 751
Query: 2488 LQYMAPEVIDHGQRGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQAAMFRVGMFKTHPP 2667
LQYMAPEVID G RGYG ADIWSFGCT VEMATG+PPF+E+ + AAMF+VG +K HP
Sbjct: 752 LQYMAPEVIDQGVRGYGPAADIWSFGCTNVEMATGKPPFIELGSAHAAMFKVGFYKKHPN 811
Query: 2668 IPTEITEKCRNFIKSCFLPEACDRPSAKDLLQDPFI 2775
IP E++ +NFI CF DRPSA LL+DPF+
Sbjct: 812 IPEELSANAKNFILRCFAISVMDRPSASQLLEDPFL 847
Score = 84.3 bits (207), Expect = 2e-14
Identities = 45/130 (34%), Positives = 78/130 (59%), Gaps = 3/130 (2%)
Frame = +1
Query: 3313 FFMLQKDSERRRSLGQFMQDYKDLIIDSWSTLLIKQSDTE---LVVTVYMLEMLLDGMRD 3483
F+ L+KDS+RR +L + + + I W +K+ D + + + LE+L+ G+RD
Sbjct: 951 FYRLKKDSQRRTTLSKVLALDESKICHIW----LKKVDADQNSIAIRKSDLEVLIRGLRD 1006
Query: 3484 FLLKKDNTKMQKMIDDIRGLLDYDTAKIGQINLALYHFSDSIQPVLRRLDIKPHWMFALS 3663
+++ ++ ++ I++++ L+ D + ++LALY F D++ VLR IKPHWMFAL
Sbjct: 1007 YIMNENEKHLEATINELKQKLNNDAVALDHLHLALYSFQDAVVCVLRYHCIKPHWMFALD 1066
Query: 3664 NLITSAVQCA 3693
NL+ AVQ A
Sbjct: 1067 NLVKRAVQAA 1076
>gi|24648284|ref|NP_477089.2| CG4720-PA [Drosophila melanogaster]
gi|23171756|gb|AAF55711.2| CG4720-PA [Drosophila melanogaster]
Length = 1367
Score = 793 bits (2049), Expect = 0.0
Identities = 438/876 (50%), Positives = 573/876 (65%), Gaps = 13/876 (1%)
Frame = +1
Query: 187 LHVVIVIDQKVQKNLRVREMALKDVQKVADTLNVNLTRIDFDKLDFGETETLDLFYNADV 366
+ VV V+D V +L R+ AL+++++ + N R+ F++LDFGET L+ FYNADV
Sbjct: 5 MDVVCVMDTAVGDHLEDRQCALEEIKQAVQSAGANFQRVQFERLDFGETNVLETFYNADV 64
Query: 367 ALVDVTVTHQQPSLCYHIGVRESMGQSYNMILTYWSPDPEYHIMDALKKTHAHLPMIVYI 546
A++D+++ QQ L YH GVRES G N ILTY D + + +LK + A+ + Y
Sbjct: 65 AIIDLSILTQQRPLSYHYGVRESFGMKEN-ILTYNDIDSKQTL--SLKLSCANYLFLSYK 121
Query: 547 HHQDSNQLQSYDKXXXXXXSKPPFARTNVPAKTITFQHRMKQVLKSVQVEASAHSREKFM 726
+ ++N + SK P A VP T Q R+K+ L+ V++++ AH REKF+
Sbjct: 122 RNAETNSCHLTSQPNSGNNSKEPNAEGRVP----TLQWRLKRKLQDVEIQSKAHMREKFL 177
Query: 727 SDLRKAREI--TDGDQKNDYLDKMRTRLDNPDVLHPDTVSLMMLSYRDNQNYGGMIRLVD 900
SD+R AR+ T+G + L +MR RLD+P VL + V M S RD Q+Y M+RLV+
Sbjct: 178 SDMRTARDTYATNGAKLQSILHEMRKRLDDPHVLSGEVVHSFMCSLRDVQDYDAMVRLVN 237
Query: 901 DLKRIPDCLKVVDTPVIRYQYAFALNRRNKDGDRDLALNTVLSLVEGTTENEEKNGPLSP 1080
DLK IP+ K V+T + + YAFALNRRN+ GDR+ AL + L +E K P
Sbjct: 238 DLKNIPNTRKYVETGNMSFLYAFALNRRNRKGDREKALESSLKALE-------KKENHFP 290
Query: 1081 DVVCLAGRIYKDKFIASNYEDRESLNSAIEWYRRAFEMSPLEYSGINLTTLLRASGEHFE 1260
D++CL GRIYKD F+ S+Y D SL AI+WYR++FE+ P EY+GINL TLL G+ F
Sbjct: 291 DMLCLCGRIYKDIFVESDYTDATSLAHAIKWYRQSFEVQPNEYAGINLATLLVIEGKEFT 350
Query: 1261 NNLEMQQIAVVLNSLLGRKGALQNLMEYWDVATYFEVSVLAENYQKACEAALMMVKLKPP 1440
N E+Q I + LN+L+G+KG+L +L EYWDVAT+FE+SVLA +Y KA +AA M KLKPP
Sbjct: 351 NTEELQHIGMTLNNLIGKKGSLSSLSEYWDVATFFEISVLANDYAKAIQAAECMFKLKPP 410
Query: 1441 VWYLKSTMENIKLINRCAATISPIEK----EKQQFLFWSEFFMEATEADTDISCPRYPVL 1608
WYLKST+ NI LI+R P E+ E+Q F FW +FF+EAT + + R+P+L
Sbjct: 411 NWYLKSTIGNISLIHRFRK--KPEERQPPIEEQVFQFWMDFFLEATNTEEVKNSIRFPIL 468
Query: 1609 ILELNKEFTPSYLTLN---NEEGTVILSHVLENSQQKKIHQSELRGIHRWHFARNNIKAV 1779
ILE K + PSY+T+N +E+ I++ L +++ + + IH + F + IK+V
Sbjct: 469 ILEPQKIYMPSYVTINMDADEKSIQIVNICLAHAK------NACKKIHDFLFVASKIKSV 522
Query: 1780 TESKRDDRQLFLYVHENSDDFNLLFPTKAHCKKAYDDMKSMA--DVADGNYQGRVLSNPD 1953
+ KRDDR +LYVH NSDDF + FP+ +K YD + M V N LSN D
Sbjct: 523 SLYKRDDRCAYLYVHHNSDDFQIYFPSTERRQKFYDMILEMTADQVVFVN-----LSN-D 576
Query: 1954 NEKIRFEYELSNSNERVVLGKGTYGTVYAARDMDTQRQIVVKEIEVKYDEEVQPLMEEIS 2133
+ I +EY+ N ++VLGKGTYGTVYAARD TQ +I +KE+ K ++VQPL EEI
Sbjct: 577 DANIEYEYDYDEQNRKMVLGKGTYGTVYAARDKQTQVRIAIKEVPEKNSQDVQPLHEEIK 636
Query: 2134 LHSTLCHANIVQYLGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLRSKWGPM--NENAMNY 2307
LHS L H NIV+YLG N F IFME VPGGSLS LL +KWGP+ NE+ M +
Sbjct: 637 LHSQLRHRNIVRYLG-----SCSENGFFKIFMEQVPGGSLSDLLETKWGPLKDNESTMAF 691
Query: 2308 YGKQILEGLKYLHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVTETFTGT 2487
Y KQILEGLKYLHE IVHRDIKGDNVLVNTYSGV KISDFGT KRLA +NP+TETFTGT
Sbjct: 692 YSKQILEGLKYLHEQDIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLARINPMTETFTGT 751
Query: 2488 LQYMAPEVIDHGQRGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQAAMFRVGMFKTHPP 2667
LQYMAPEVID G RGYG ADIWSFGCT VEMATG+PPF+E+ + AAMF+VG +K HP
Sbjct: 752 LQYMAPEVIDQGVRGYGPAADIWSFGCTNVEMATGKPPFIELGSAHAAMFKVGFYKKHPN 811
Query: 2668 IPTEITEKCRNFIKSCFLPEACDRPSAKDLLQDPFI 2775
IP E++ +NFI CF DRPSA LL+DPF+
Sbjct: 812 IPEELSANAKNFILRCFAISVMDRPSASQLLEDPFL 847
Score = 87.0 bits (214), Expect = 3e-15
Identities = 46/130 (35%), Positives = 79/130 (60%), Gaps = 3/130 (2%)
Frame = +1
Query: 3313 FFMLQKDSERRRSLGQFMQDYKDLIIDSWSTLLIKQSDTE---LVVTVYMLEMLLDGMRD 3483
F+ L+KDS+RR +L + + + I D W +K+ D + + + LE+L+ G+RD
Sbjct: 951 FYRLKKDSQRRTTLSKVLALDESKICDIW----LKKVDADQNSIAIRKSDLEVLIRGLRD 1006
Query: 3484 FLLKKDNTKMQKMIDDIRGLLDYDTAKIGQINLALYHFSDSIQPVLRRLDIKPHWMFALS 3663
+++ ++ ++ I++++ L+ D + ++LALY F D++ VLR IKPHWMFAL
Sbjct: 1007 YIMNENEKHLEATINELKQKLNNDAVALDHLHLALYSFQDAVVCVLRYHCIKPHWMFALD 1066
Query: 3664 NLITSAVQCA 3693
NL+ AVQ A
Sbjct: 1067 NLVKRAVQAA 1076
>gi|27374208|gb|AAO00972.1| Pk92B-PA [Drosophila erecta]
Length = 1307
Score = 789 bits (2038), Expect = 0.0
Identities = 499/1176 (42%), Positives = 663/1176 (55%), Gaps = 13/1176 (1%)
Frame = +1
Query: 205 IDQKVQKNLRVREMALKDVQKVADTLNVNLTRIDFDKLDFGETETLDLFYNADVALVDVT 384
+D V +L R AL+++++ + N R+ F++LDFGET L+ FYNADVA++D++
Sbjct: 1 MDTSVGDHLEDRLCALEEIKQAVQSAGANFQRVQFERLDFGETNVLETFYNADVAVIDLS 60
Query: 385 VTHQQPSLCYHIGVRESMGQSYNMILTYWSPDPEYHIMDALKKTHAHLPMIVYIHHQDSN 564
+ QQ L YH GVRES G N ILTY D E +LK + A+ + Y + ++N
Sbjct: 61 ILPQQRPLSYHYGVRESFGMKEN-ILTY--NDIESKQTLSLKLSCANYLFLSYKRNAETN 117
Query: 565 QLQSYDKXXXXXXSKPPFARTNVPAKTITFQHRMKQVLKSVQVEASAHSREKFMSDLRKA 744
+ +K P A VP T Q R+K+ L+ V++++ AH REKF+SD+R A
Sbjct: 118 SCHLTSQPNSNNNNKEPAAEGRVP----TLQWRLKRKLQDVEIQSKAHMREKFLSDMRTA 173
Query: 745 REI--TDGDQKNDYLDKMRTRLDNPDVLHPDTVSLMMLSYRDNQNYGGMIRLVDDLKRIP 918
R+ T+G + L +MR RLD+P VL + V M S RD Q+Y M+RLV+DLK IP
Sbjct: 174 RDTYATNGAKLQSILHEMRKRLDDPHVLSGEVVHSFMCSLRDVQDYDAMVRLVNDLKNIP 233
Query: 919 DCLKVVDTPVIRYQYAFALNRRNKDGDRDLALNTVLSLVEGTTENEEKNGPLSPDVVCLA 1098
+ K V+T + + YAFALNRRN+ GDR+ AL + L +E K PD++CL
Sbjct: 234 NTRKYVETGNMSFLYAFALNRRNRKGDREKALESSLKALE-------KKENHFPDMLCLC 286
Query: 1099 GRIYKDKFIASNYEDRESLNSAIEWYRRAFEMSPLEYSGINLTTLLRASGEHFENNLEMQ 1278
GRIYKD F+ S+Y D SL AI+WYR++FE+ P EY+GINL TLL G+ F N E+Q
Sbjct: 287 GRIYKDIFVESDYTDATSLAHAIKWYRQSFEVQPNEYAGINLATLLVIEGKEFTNTEELQ 346
Query: 1279 QIAVVLNSLLGRKGALQNLMEYWDVATYFEVSVLAENYQKACEAALMMVKLKPPVWYLKS 1458
I + LN+L+G+KG+L +L EYWDVAT+FE+SVLA++Y KA +AA M KLKPP WYLKS
Sbjct: 347 HIGMTLNNLIGKKGSLSSLSEYWDVATFFEISVLAKDYAKAIQAAECMFKLKPPNWYLKS 406
Query: 1459 TMENIKLINRCAATISPIEK----EKQQFLFWSEFFMEATEADTDISCPRYPVLILELNK 1626
T+ NI LI+R P E+ E+Q F FW +FF+EAT + + R+P+LILE K
Sbjct: 407 TIGNISLIHRFRK--KPEERQPPIEEQVFQFWMDFFLEATNTEEVKNSIRFPILILEPQK 464
Query: 1627 EFTPSYLTLN---NEEGTVILSHVLENSQQKKIHQSELRGIHRWHFARNNIKAVTESKRD 1797
+ PSY+T+N +E+ I+++ L +++ + + IH + F + IK+V+ KRD
Sbjct: 465 IYMPSYVTINMDADEKSIQIVNNCLAHAK------NACKKIHDFLFVASKIKSVSLYKRD 518
Query: 1798 DRQLFLYVHENSDDFNLLFPTKAHCKKAYDDMKSMA--DVADGNYQGRVLSNPDNEKIRF 1971
DR +LYVH NSDDF + FP+ +K YD + M V N LSN D+ +I +
Sbjct: 519 DRCAYLYVHHNSDDFQIYFPSTERRQKFYDLILEMTADQVVFVN-----LSN-DDAQIEY 572
Query: 1972 EYELSNSNERVVLGKGTYGTVYAARDMDTQRQIVVKEIEVKYDEEVQPLMEEISLHSTLC 2151
EY+ N ++VLGKGTYGTVYAARD TQ +I +KE+ K ++VQPL EEI LHS L
Sbjct: 573 EYDYDEQNRKMVLGKGTYGTVYAARDKQTQVRIAIKEVPEKNSQDVQPLHEEIKLHSQLR 632
Query: 2152 HANIVQYLGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLRSKWGPM--NENAMNYYGKQIL 2325
H NIV+YLG +DG F IFME VPGGSLS LL +KWGP+ NE+ M +Y KQIL
Sbjct: 633 HRNIVRYLGSR--SEDG---FFKIFMEQVPGGSLSDLLETKWGPLKDNESTMAFYSKQIL 687
Query: 2326 EGLKYLHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVTETFTGTLQYMAP 2505
EGLKYLHE IVHRDIKGDNVLVNTYSGV KISDFGT KRLA +NP+TETFTGTLQYMAP
Sbjct: 688 EGLKYLHEQDIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLARINPMTETFTGTLQYMAP 747
Query: 2506 EVIDHGQRGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQAAMFRVGMFKTHPPIPTEIT 2685
EVID G RGYG ADIWSFGCT VEMATG+PPF+E+ QAAMF+VG +K HP IP E++
Sbjct: 748 EVIDQGVRGYGPAADIWSFGCTNVEMATGKPPFIELGCAQAAMFKVGYYKKHPNIPEELS 807
Query: 2686 EKCRNFIKSCFLPEACDRPSAKDLLQDPFIYHNHHSISRTRSGSINKKPATKIELNHDKE 2865
+NFI CF DRPSA LL+DPF+ + +PA I
Sbjct: 808 ANAKNFILRCFAISVMDRPSASQLLEDPFLQEKPRKV----------RPALPI------- 850
Query: 2866 KKEKSKNQREMLRSTSHIGGMGVVERSPPTPEPMSATLTAGFSHVHSQTVSNALSTAREE 3045
E RS S + V +S P P+S T +++N S +E
Sbjct: 851 -------NTEFGRSIS-VPADRFVHKSTP---PLSYNTTCNTPTTPEFSITNTSSVDIDE 899
Query: 3046 KKLHLKIDHARNRTFXXXXXXXXXXXXAGTNMSHPGFQLSQPSSPIVDDTNHPHLIVSPI 3225
+ + RN SH GF LS P + S
Sbjct: 900 LPSNQFMLERRN--------------------SH-GFLLS------------PEIEPSTP 926
Query: 3226 SLNTMGSPLSSAALLNRTIXXXXXXXXXRFFMLQKDSERRRSLGQFMQDYKDLIIDSWST 3405
SL T S S F+ L+KDS+RR +L + + + I D W
Sbjct: 927 SLRTSISETSE---------------TDGFYRLKKDSQRRTTLSKVLALDESKICDIW-- 969
Query: 3406 LLIKQSDTELVVTVYMLEMLLDGMRDFLLKKDNTKMQKMIDDIRGLLDYDTAKIGQINLA 3585
+K+ D + ++K + + D + +L Y K
Sbjct: 970 --LKKVDAD--------------QHSIAIRKSDLE-----DAVVCVLRYHCIK------- 1001
Query: 3586 LYHFSDSIQPVLRRLDIKPHWMFALSNLITSAVQCA 3693
PHWMFAL NL+ AVQ A
Sbjct: 1002 ------------------PHWMFALDNLVKRAVQAA 1019
>gi|27374376|gb|AAO01114.1| Pk92B-PA [Drosophila pseudoobscura]
Length = 1310
Score = 775 bits (2001), Expect = 0.0
Identities = 442/936 (47%), Positives = 586/936 (62%), Gaps = 11/936 (1%)
Frame = +1
Query: 187 LHVVIVIDQKVQKNLRVREMALKDVQKVADTLNVNLTRIDFDKLDFGETETLDLFYNADV 366
+ VV VID V +L R AL++V++ N R+ F+KLDFGE+ ++ FYNADV
Sbjct: 1 MDVVCVIDTVVGDHLEDRICALEEVKRAVQAAGANFQRVQFEKLDFGESNVMETFYNADV 60
Query: 367 ALVDVTVTHQQPSLCYHIGVRESMGQSYNMILTYWSPDPEYHIMDALKKTHAHLPMIVYI 546
A++D++V QQ +L YH GVRES G +IL Y D E +LK + + + Y
Sbjct: 61 AVIDLSVLAQQRTLSYHYGVRESFGMK-EIILIY--NDVESKQTLSLKVSCGNYLFLSYK 117
Query: 547 HHQDSNQLQSYDKXXXXXXSKPPFARTNVPAKTITFQHRMKQVLKSVQVEASAHSREKFM 726
+ +SN ++P + T Q R+++ L+ V++++ AH REKF+
Sbjct: 118 LNAESNSC--------LLTNQPNSKDQPGDGRVSTLQGRLRRKLQDVEIQSKAHMREKFL 169
Query: 727 SDLRKAREI--TDGDQKNDYLDKMRTRLDNPDVLHPDTVSLMMLSYRDNQNYGGMIRLVD 900
SD+R AR+ T+G + L +MR RLD+P VL + V M S RD Q+Y M+RLV+
Sbjct: 170 SDMRTARDTYATNGAKLQSILHEMRKRLDDPHVLSGEVVHSFMCSLRDVQDYDAMVRLVN 229
Query: 901 DLKRIPDCLKVVDTPVIRYQYAFALNRRNKDGDRDLALNTVLSLVEGTTENEEKNGPLSP 1080
DLK IP+ K V+ + + YAFALNRRN+ GDR+ AL + L +E K P
Sbjct: 230 DLKNIPNTRKFVEAGNMSFLYAFALNRRNRKGDREKALESSLKALE-------KKENHFP 282
Query: 1081 DVVCLAGRIYKDKFIASNYEDRESLNSAIEWYRRAFEMSPLEYSGINLTTLLRASGEHFE 1260
D++CL GRIYKD F+ S+Y D SL AI+WYR++FE+ P EY+GINL TLL G+ F
Sbjct: 283 DMLCLCGRIYKDIFVESDYTDATSLAHAIKWYRQSFEVQPNEYAGINLATLLVIEGKEFS 342
Query: 1261 NNLEMQQIAVVLNSLLGRKGALQNLMEYWDVATYFEVSVLAENYQKACEAALMMVKLKPP 1440
N E+Q I + LN+L+G+KG+L L EYWDVAT+FE+SVLAE+Y KA +AA M KLKPP
Sbjct: 343 NTEELQHIGMTLNNLIGKKGSLSTLSEYWDVATFFEISVLAEDYAKAIQAAECMFKLKPP 402
Query: 1441 VWYLKSTMENIKLINRCAAT----ISPIEKEKQQFLFWSEFFMEATEADTDISCPRYPVL 1608
WYLKST+ NI LI+R + PIE+ Q F FW +FF+EAT + + R+P+L
Sbjct: 403 NWYLKSTIGNISLIHRFRKKPEDRMPPIEE--QVFQFWMDFFLEATNTEEIKNSIRFPIL 460
Query: 1609 ILELNKEFTPSYLTLN---NEEGTVILSHVLENSQQKKIHQSELRGIHRWHFARNNIKAV 1779
ILE K + PSY+T+N +E+ I++ L +S+ + + +H + F + IK+V
Sbjct: 461 ILEPQKIYMPSYVTINMDADEKSIQIVNICLAHSK------NTCKKLHDFIFVASKIKSV 514
Query: 1780 TESKRDDRQLFLYVHENSDDFNLLFPTKAHCKKAYDDMKSMADVADGNYQGRVLSNPDNE 1959
+ KRDDR +LYVH NSDDF + FP+ +K YD + M + + V + D+
Sbjct: 515 SLYKRDDRCAYLYVHHNSDDFQIYFPSSECRQKFYDLILEMT----ADQEVFVNLSNDDA 570
Query: 1960 KIRFEYELSNSNERVVLGKGTYGTVYAARDMDTQRQIVVKEIEVKYDEEVQPLMEEISLH 2139
+I +EY+ N ++VLGKGTYGTVYAARD TQ +I +KE+ K ++VQPL EEI LH
Sbjct: 571 QIEYEYDYDEQNRKMVLGKGTYGTVYAARDKQTQVRIAIKEVPEKNSQDVQPLHEEIKLH 630
Query: 2140 STLCHANIVQYLGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLRSKWGPM--NENAMNYYG 2313
S L H NIVQYLG +DG F IFME VPGGSLS LL +KWGP+ NE+ M +Y
Sbjct: 631 SQLRHRNIVQYLGSR--SEDG---FFKIFMEQVPGGSLSDLLETKWGPLKDNESTMAFYS 685
Query: 2314 KQILEGLKYLHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVTETFTGTLQ 2493
KQILEGLKYLHE IVHRDIKGDNVLVNTYSGV KISDFGT KRLA +NP+TETFTGTLQ
Sbjct: 686 KQILEGLKYLHEQDIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLARINPMTETFTGTLQ 745
Query: 2494 YMAPEVIDHGQRGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQAAMFRVGMFKTHPPIP 2673
YMAPEVID G RGYG ADIWSFGCT VEMATG+PPF+E+ QAAMF+VG K HP IP
Sbjct: 746 YMAPEVIDQGVRGYGPAADIWSFGCTNVEMATGKPPFIELGCAQAAMFKVGYHKKHPNIP 805
Query: 2674 TEITEKCRNFIKSCFLPEACDRPSAKDLLQDPFIYHNHHSISRTRSGSINKKPATKIELN 2853
E++ +NFI CF DRPSA LL+DPF+ +KP + +N
Sbjct: 806 VELSTNAKNFILRCFAISVLDRPSASQLLEDPFL------------ADKPRKPRPGLPIN 853
Query: 2854 HDKEKKEKSKNQREMLRSTSHIGGMGVVERSPPTPE 2961
D + R + ++T+ + +P TPE
Sbjct: 854 TDFGRSISVPADRLVNKTTAPL-TYNTTHNTPTTPE 888
Score = 38.9 bits (89), Expect = 1.0
Identities = 19/31 (61%), Positives = 21/31 (67%)
Frame = +1
Query: 3601 DSIQPVLRRLDIKPHWMFALSNLITSAVQCA 3693
D + VLR IKPHWMFAL NL+ AVQ A
Sbjct: 988 DVVVCVLRYHCIKPHWMFALDNLVKRAVQAA 1018
>gi|27374347|gb|AAO01088.1| Pk92B-PA [Drosophila willistoni]
Length = 1334
Score = 768 bits (1982), Expect = 0.0
Identities = 429/873 (49%), Positives = 565/873 (64%), Gaps = 10/873 (1%)
Frame = +1
Query: 187 LHVVIVIDQKVQKNLRVREMALKDVQKVADTLNVNLTRID-FDKLDFGETETLDLFYNAD 363
+ VV VID + +L R AL++V+ + N R+ F++LDFGET L FY+AD
Sbjct: 1 MDVVCVIDTVIGDHLDDRTCALEEVKLAVQSAGANFQRVQQFERLDFGETNALATFYDAD 60
Query: 364 VALVDVTVTHQQPSLCYHIGVRESMGQSYNMILTYWSPDPEYHIMDALKKTHAHLPMIVY 543
VA++D+++ QQ L YH GVRES G N+++ D E +LK + A+ + Y
Sbjct: 61 VAIIDLSILTQQRPLSYHYGVRESFGMKENILIYN---DVESKQTLSLKLSCANYLFLSY 117
Query: 544 IHHQDSNQLQSYDKXXXXXXSKPPFARTNVPAKTITFQHRMKQVLKSVQVEASAHSREKF 723
++++N ++ AR VP T Q R+K+ L+ V++++ AH REKF
Sbjct: 118 KRNEETNTCNLTNQANAKELPAAEGARV-VP----TLQSRLKRKLQDVEIQSKAHMREKF 172
Query: 724 MSDLRKAREI--TDGDQKNDYLDKMRTRLDNPDVLHPDTVSLMMLSYRDNQNYGGMIRLV 897
+SD+R AR+ T+G + L MR RLD+P VL + V M S RD Q+Y M+RLV
Sbjct: 173 LSDMRAARDTYATNGAKLQSILHDMRKRLDDPHVLSGEVVHSFMCSLRDVQDYDAMVRLV 232
Query: 898 DDLKRIPDCLKVVDTPVIRYQYAFALNRRNKDGDRDLALNTVLSLVEGTTENEEKNGPLS 1077
+DLK IP+ K V+T + + YAFALNRRN+ GDR AL + L +E K
Sbjct: 233 NDLKNIPNTRKYVETGNMSFLYAFALNRRNRKGDRKKALESSLKALE-------KKENHF 285
Query: 1078 PDVVCLAGRIYKDKFIASNYEDRESLNSAIEWYRRAFEMSPLEYSGINLTTLLRASGEHF 1257
PD++CL GRIYKD F+ S+Y D +SL +AI+WYR++FE+ P EY+GINL TLL G+ F
Sbjct: 286 PDMLCLCGRIYKDIFVESDYTDAKSLANAIKWYRQSFEVQPNEYAGINLATLLVIEGKEF 345
Query: 1258 ENNLEMQQIAVVLNSLLGRKGALQNLMEYWDVATYFEVSVLAENYQKACEAALMMVKLKP 1437
N E+Q I + LN+L+G+KG+L L EYWDVAT+FE+SVLA++Y KA +AA M KLKP
Sbjct: 346 TNTEELQHIGMTLNNLIGKKGSLPTLSEYWDVATFFEISVLAKDYAKAIQAAECMFKLKP 405
Query: 1438 PVWYLKSTMENIKLINRCAATISPIEK--EKQQFLFWSEFFMEATEADTDISCPRYPVLI 1611
P WYLKST+ NI LI+R E+Q F FW +FF+EAT + + R+P+LI
Sbjct: 406 PNWYLKSTIGNISLIHRFRKKSEERLPTIEEQVFQFWMDFFLEATNTEEIKNSIRFPILI 465
Query: 1612 LELNKEFTPSYLTLN---NEEGTVILSHVLENSQQKKIHQSELRGIHRWHFARNNIKAVT 1782
LE K + PSY+T+N E+ I++ L +++ + + +H + F + IK+V+
Sbjct: 466 LEPQKIYMPSYVTINMDAEEKSIQIVNICLAHTK------NACKKLHDFLFVASKIKSVS 519
Query: 1783 ESKRDDRQLFLYVHENSDDFNLLFPTKAHCKKAYDDMKSMADVADGNYQGRVLSNPDNEK 1962
KRDDR +LYVH NSDDF + FP+ +K Y+ + M + + V N D +
Sbjct: 520 LYKRDDRCAYLYVHHNSDDFQIYFPSTECRQKFYNLILEMT----ADQEVFVNLNNDEAQ 575
Query: 1963 IRFEYELSNSNERVVLGKGTYGTVYAARDMDTQRQIVVKEIEVKYDEEVQPLMEEISLHS 2142
I +EY+ N ++VLGKGTYGTVYAARD TQ +I +KE+ K ++VQPL EEI LHS
Sbjct: 576 IEYEYDYDEQNRKMVLGKGTYGTVYAARDKQTQVRIAIKEVPEKNSQDVQPLHEEIKLHS 635
Query: 2143 TLCHANIVQYLGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLRSKWGPM--NENAMNYYGK 2316
L H NIVQYLG +DG F IFME VPGGSLS LL +KWGP+ NE+ M +Y K
Sbjct: 636 QLRHRNIVQYLGSR--SEDG---FFKIFMEQVPGGSLSDLLETKWGPLKDNESTMAFYSK 690
Query: 2317 QILEGLKYLHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVTETFTGTLQY 2496
QILEGLKYLHE IVHRDIKGDNVLVNTYSGV KISDFGT KRLA +NP+TETFTGTLQY
Sbjct: 691 QILEGLKYLHEQDIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLARINPMTETFTGTLQY 750
Query: 2497 MAPEVIDHGQRGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQAAMFRVGMFKTHPPIPT 2676
MAPEVID G RGYG ADIWSFGCT VEMATG+PPF+E+ QAAMF+VG +K HP IP
Sbjct: 751 MAPEVIDQGVRGYGPAADIWSFGCTNVEMATGKPPFIELGCAQAAMFKVGYYKKHPNIPE 810
Query: 2677 EITEKCRNFIKSCFLPEACDRPSAKDLLQDPFI 2775
E+++ +NFI CF DRPSA LL DPF+
Sbjct: 811 ELSQNAKNFILRCFAISVMDRPSALQLLDDPFL 843
Score = 44.7 bits (104), Expect = 0.019
Identities = 53/182 (29%), Positives = 73/182 (39%), Gaps = 1/182 (0%)
Frame = +1
Query: 3151 GFQLSQPSSPIVDDTNHPHLIVSPISLNTM-GSPLSSAALLNRTIXXXXXXXXXRFFMLQ 3327
G +S P+ +V H P+S NT +P + + T F+L
Sbjct: 861 GRSISVPADRLV------HKTTPPLSYNTTCNTPTTPELEVTHTSSVDIDELPSNQFLL- 913
Query: 3328 KDSERRRSLGQFMQDYKDLIIDSWSTLLIKQSDTELVVTVYMLEMLLDGMRDFLLKKDNT 3507
ERR S G + + S T + + S+T+ Y L+ D R L K
Sbjct: 914 ---ERRNSSGFLLSPEIEPQTPSLRTSISETSETD---GFYRLKK--DSQRRTTLSKVLA 965
Query: 3508 KMQKMIDDIRGLLDYDTAKIGQINLALYHFSDSIQPVLRRLDIKPHWMFALSNLITSAVQ 3687
+ I DI L A I + D++ VLR IKPHWMFAL NL+ AVQ
Sbjct: 966 LDEPKICDI--WLKKINADQNSIAIRKSDLEDAVVSVLRFHCIKPHWMFALDNLVKRAVQ 1023
Query: 3688 CA 3693
A
Sbjct: 1024 AA 1025
>gi|31204665|ref|XP_311281.1| ENSANGP00000001618 [Anopheles gambiae]
gi|21294708|gb|EAA06853.1| ENSANGP00000001618 [Anopheles gambiae str.
PEST]
Length = 1057
Score = 747 bits (1929), Expect = 0.0
Identities = 468/1163 (40%), Positives = 656/1163 (56%), Gaps = 14/1163 (1%)
Frame = +1
Query: 238 REMALKDVQKVADTLNVNLTRIDFDKLDFGETET--LDLFYNADVALVDVTVTHQQPSLC 411
R+ AL++VQ+ + NL + FD LD+ L+ FYNADV +VD++V QQ +LC
Sbjct: 4 RKAALEEVQQACAAVGANLQLLPFDVLDYHNENNNKLEYFYNADVVVVDLSVQTQQSTLC 63
Query: 412 YHIGVRESMGQSYNMILTYWSPDPEYHIMDALKKTHAHLPMIVYIHHQDSNQLQSYDKXX 591
Y +GVRES N+++ D + +K + + + Y H++ + +
Sbjct: 64 YLLGVRESFKMKENIVIYN---DTQTEATLRMKISCGNYQFLSYRLHENGGAIVT-SPLK 119
Query: 592 XXXXSKPPFARTNVPAKTITFQHRMKQVLKSVQVEASAHSREKFMSDLRKAREITDG--D 765
+ A + + + T ++++ + V++++ H REKF++DLR R+ G +
Sbjct: 120 LEETAGTAAAASQLAQQPTTLAVALRRLFQDVEIQSKTHLREKFLADLRSLRDQHAGNVE 179
Query: 766 QKNDYLDKMRTRLDNPDVLHPDTVSLMMLSYRDNQNYGGMIRLVDDLKRIPDCLKVVDTP 945
+ L +R RLD+P VL D + ML+ RD Q+Y M++LVDDL+ IP+ ++T
Sbjct: 180 ELQRMLRNLRKRLDDPQVLSKDILQTYMLALRDVQDYDAMVQLVDDLQTIPNKQSYINTG 239
Query: 946 VIRYQYAFALNRRNKDGDRDLALNTVLSLVEGTTENEEKNGPLSPDVVCLAGRIYKDKFI 1125
+ Y YAFALNRRN +GDR+ AL T T+ EK PD++CL GRIYKD F+
Sbjct: 240 HMHYLYAFALNRRNHEGDRERALRTC-------TKALEKKENHFPDMLCLYGRIYKDIFV 292
Query: 1126 ASNYEDRESLNSAIEWYRRAFEMSPLEYSGINLTTLLRASGEHFENNLEMQQIAVVLNSL 1305
SN+ DRESL +AI WYR++FE+ P E++GINL TLL G+ F ++ E+Q I + LN+L
Sbjct: 293 ESNHTDRESLKNAIIWYRKSFEVQPNEFAGINLATLLVIDGKDFTDS-ELQHIGMKLNNL 351
Query: 1306 LGRKGALQNLMEYWDVATYFEVSVLAENYQKACEAALMMVKLKPPVWYLKSTMENIKLIN 1485
+G+KG+L + +YW+VATYFE+SVLAENY KA +AA M KL+PP WYLKST+ NI LI+
Sbjct: 352 IGKKGSLAQIKDYWNVATYFEISVLAENYAKAIQAAECMFKLRPPKWYLKSTIGNITLID 411
Query: 1486 RCAA-TISP--IEKEKQQFLFWSEFFMEATEADTDISCPRYPVLILELNKEFTPSYLTLN 1656
R T P I E+Q F FW EFF+EAT + S R+P+LILE K + PSY++++
Sbjct: 412 RARKRTEEPAGISIEQQIFQFWMEFFLEATAREPS-SMVRFPILILEPQKIYMPSYVSIH 470
Query: 1657 N--EEGTVILSHVLENSQQKKIHQSELRGIHRWHFARNNIKAVTESKRDDRQLFLYVHEN 1830
E+ ++ +S+V + + + +H ++F + IK+V+ KRD+R +LYVH N
Sbjct: 471 MDAEQKSIDISNVCQQHAKGTCLK-----LHDFNFLASQIKSVSLYKRDERCAYLYVHHN 525
Query: 1831 SDDFNLLFPTKAHCKKAYDDM--KSMADVADGNYQGRVLSNPDNEKIRFEYELSNSNERV 2004
SDDF + FP+ C++ + D+ + AD G + + +++++EY+L + +R+
Sbjct: 526 SDDFQMFFPS-VQCRQTFYDLILQMTADQGSG-FIDLSAAETTADELKYEYDLDDEGQRI 583
Query: 2005 VLGKGTYGTVYAARDMDTQRQIVVKEIEVKYDEEVQPLMEEISLHSTLCHANIVQYLGCD 2184
+LGKGTYG VYAARD+ TQ +I VKE+ + +VQPL EEI LHS L H NIVQY G
Sbjct: 584 LLGKGTYGAVYAARDLTTQVKIAVKEVYERNTHDVQPLHEEIKLHSQLRHRNIVQYWG-- 641
Query: 2185 LVGKDGSNDHFLIFMEHVPGGSLSSLLRSKWGPM--NENAMNYYGKQILEGLKYLHELKI 2358
N +F IFME VPGGSLS+LL SKWGP+ +E + +Y +QILEGLKYLH+ KI
Sbjct: 642 ---SKSENQYFKIFMEQVPGGSLSALLSSKWGPLKDSETTIAFYSRQILEGLKYLHDQKI 698
Query: 2359 VHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVTETFTGTLQYMAPEVIDHGQRGYG 2538
VHRDIKG NVLVNTYSGV KISDFGT KRLAG+NP TETFTGTLQYMAPEVID G RGYG
Sbjct: 699 VHRDIKGGNVLVNTYSGVVKISDFGTSKRLAGINPATETFTGTLQYMAPEVIDQGVRGYG 758
Query: 2539 APADIWSFGCTMVEMATGRPPFVEMQNPQAAMFRVGMFKTHPPIPTEITEKCRNFIKSCF 2718
ADIWSFGCT+VEMATG+PPFVE+ PQAAMF+VG +KTHP IP E++ +NFI CF
Sbjct: 759 PAADIWSFGCTVVEMATGKPPFVELGCPQAAMFKVGFYKTHPTIPEELSSMAKNFILRCF 818
Query: 2719 LPEACDRPSAKDLLQDPFIYHNHHSISRTRSGSINKKPATKIELNHDKEKKEKSKNQREM 2898
R +A +LL+DPF+ H + + S S +T L H E
Sbjct: 819 EVNVDKRATATELLEDPFLCEKHKKMRPSFSSS-----STISGLPH--------PGASEF 865
Query: 2899 LRSTSHIGGMGVVERSPPTPEPMSATLTAGFSHVHSQTVSNALSTAREEKKLHLKIDHAR 3078
RS S P S TLT S T + + T + L++D A
Sbjct: 866 SRSV-----------SMPADRHNSKTLTTQESSASCNTPTFSSETENLAETPSLEMDSAE 914
Query: 3079 NRTFXXXXXXXXXXXXAGTNMSHPGFQLSQPSSPIVDDTNHPHLIVSPISLNT-MGSPLS 3255
+ FQL++ SS L+ I + T S L
Sbjct: 915 QTSTV--------------------FQLNRRSS-------SGGLLSPEIDITTSTASKLP 947
Query: 3256 SAALLNRTIXXXXXXXXXRFFMLQKDSERRRSLGQFMQDYKDLIIDSWSTLLIKQSDTEL 3435
A N + F++L+KDS+RR++L + + I + W T + ++ EL
Sbjct: 948 LAGDANES---------DGFYLLKKDSQRRQTLDKVLCHDVTKICELWLTKIEPDANQEL 998
Query: 3436 VVTVYMLEMLLDGMRDFLLKKDNTKMQKMIDDIRGLLDYDTAKIGQINLALYHFSDSIQP 3615
+T RD L +++
Sbjct: 999 AIT-----------RDHL-------------------------------------NTVIT 1010
Query: 3616 VLRRLDIKPHWMFALSNLITSAV 3684
VLR +IKPHWMFAL NL+ SAV
Sbjct: 1011 VLRSHNIKPHWMFALENLVKSAV 1033
>gi|42662661|ref|XP_372199.2| similar to MAP/ERK kinase kinase 5;
apoptosis signal regulating kinase [Homo sapiens]
Length = 1208
Score = 718 bits (1853), Expect = 0.0
Identities = 422/1023 (41%), Positives = 582/1023 (56%), Gaps = 12/1023 (1%)
Frame = +1
Query: 661 RMKQVLKSVQVEASAHSREKFMSDLRKAREITDGDQKNDYLDKMRTRLDNPDVLHPDTVS 840
R +LK + V + + +E ++D+RKARE G++ L +++ R+DN +VL D +
Sbjct: 112 RFISLLKDIHVTSCVYYKETLLNDIRKAREKYQGEELAKELARIKLRMDNTEVLTSDIII 171
Query: 841 LMMLSYRDNQNYGGMIRLVDDLKRIPDCLKVVDTPVIRYQYAFALNRRNKDGDRDLALNT 1020
++LSYRD Q+Y M++LV+ L+ +P C + D I++ YAFALNRRN GDR+ AL
Sbjct: 172 NLLLSYRDIQDYDAMVKLVETLEMLPTC-DLADQHNIKFHYAFALNRRNSTGDREKALQI 230
Query: 1021 VLSLVEGTTENEEKNGPLSPDVVCLAGRIYKDKFIASNYEDRESLNSAIEWYRRAFEMSP 1200
+L +++ PD+ CL GRIYKD F+ S+ +D S +SAIEWYR+ FE+
Sbjct: 231 MLQVLQSCDHP-------GPDMFCLCGRIYKDIFLDSDCKDDTSRDSAIEWYRKGFELQS 283
Query: 1201 LEYSGINLTTLLRASGEHFENNLEMQQIAVVLNSLLGRKGALQNLMEYWDVATYFEVSVL 1380
YSGINL LL +G+ FE +LE+++I V LNSLLGRKG+L+ + YWDV +F VS+L
Sbjct: 284 SLYSGINLAVLLIVAGQQFETSLELRKIGVRLNSLLGRKGSLEKMNNYWDVGQFFSVSML 343
Query: 1381 AENYQKACEAALMMVKLKPPVWYLKSTMENIKLINRCAATISPIEKEKQQFLFWSEFFME 1560
A + KA +AA + KLKPPVWYL+S ++N+ LI R TI +++ FW + E
Sbjct: 344 AHDVGKAVQAAERLFKLKPPVWYLRSLVQNLLLIRRFKKTIIEHSPRQERLNFWLDIIFE 403
Query: 1561 ATEADTDISCPRYPVLILELNKEFTPSYLTLNNE--EGTVILSHVLENSQQKKIHQSELR 1734
AT T+ R+PVL++E K + PSY+++NNE E TV L HV +E++
Sbjct: 404 ATNEVTNGL--RFPVLVIEPTKVYQPSYVSINNEAEERTVSLWHV---------SPTEMK 452
Query: 1735 GIHRWHFARNNIKAVTESKRDDRQLFLYVHENSDDFNLLFPTKAHCKKAYDDMKSMADVA 1914
+H W+F ++IK ++ SK D+R FLYVH+NSDDF + F T+ C + + +K M
Sbjct: 453 QMHEWNFTASSIKGISLSKFDERCCFLYVHDNSDDFQIYFSTEEQCSRFFSLVKEMITNT 512
Query: 1915 DGNYQGRVLSNPDNEKIRFEYELSNSNERVVLGKGTYGTVYAARDMDTQRQIVVKEIEVK 2094
G+ + D + + +EY+ + ERVVLGKGTYG VYA RD+ Q +I +KEI +
Sbjct: 513 AGSTV-ELEGETDGDTLEYEYDHDANGERVVLGKGTYGIVYAGRDLSNQVRIAIKEIPER 571
Query: 2095 YDEEVQ----------PLMEEISLHSTLCHANIVQYLGCDLVGKDGSNDHFLIFMEHVPG 2244
+VQ PL EEI+LH L H NIVQYLG N + IFME VPG
Sbjct: 572 DSRQVQAGLPHFGYSQPLHEEIALHKYLKHRNIVQYLG-----SVSENGYIKIFMEQVPG 626
Query: 2245 GSLSSLLRSKWGPMNENAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLVNTYSGVCKIS 2424
GSLS+LLRSKWGPM E + +Y KQILEGLKYLHE +IVHRDIKGDNVLVNTYSGV KIS
Sbjct: 627 GSLSALLRSKWGPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKIS 686
Query: 2425 DFGTCKRLAGLNPVTETFTGTLQYMAPEVIDHGQRGYGAPADIWSFGCTMVEMATGRPPF 2604
DFGT KRLAG+NP TETFTGTLQYMAPE+ID G RGYGAPADIWS GCT++EMAT +PPF
Sbjct: 687 DFGTSKRLAGVNPCTETFTGTLQYMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSKPPF 746
Query: 2605 VEMQNPQAAMFRVGMFKTHPPIPTEITEKCRNFIKSCFLPEACDRPSAKDLLQDPFIYHN 2784
E+ PQAAMF+VGMFK HP IP ++ + R FI SCF P DP
Sbjct: 747 HELGEPQAAMFKVGMFKIHPEIPEALSAEARAFILSCFEP-------------DPH---- 789
Query: 2785 HHSISRTRSGSINKKPATKIELNHDKEKKEKSKNQREMLRSTSHIGGMGVVERSPPTPEP 2964
K AT EL + ++ +K ++ + G GVV P EP
Sbjct: 790 --------------KRATTAELLREGFLRQVNKGKKNRIAFKPSEGPRGVVLALPTQGEP 835
Query: 2965 MSATLTAGFSHVHSQTVSNALSTAREEKKLHLKIDHARNRTFXXXXXXXXXXXXAGTNMS 3144
M+ T+ H S+A A E+
Sbjct: 836 MA---TSSSEHGSVSPDSDAQPDALFER--------------------------TRAPRH 866
Query: 3145 HPGFQLSQPSSPIVDDTNHPHLIVSPISLNTMGSPLSSAALLNRTIXXXXXXXXXRFFML 3324
H G LS P S+AL +R + F+L
Sbjct: 867 HLGHLLSVPDE--------------------------SSALEDRGLASSPEDRDQGLFLL 900
Query: 3325 QKDSERRRSLGQFMQDYKDLIIDSWSTLLIKQSDTELVVTVYMLEMLLDGMRDFLLKKDN 3504
+KDSERR L + + + ++ + + + QS EL ++V ++ ++ +RDF+ ++
Sbjct: 901 RKDSERRAILYKILWEEQNQVASNLQEC-VAQSSEELHLSVGHIKQIIGILRDFIRSPEH 959
Query: 3505 TKMQKMIDDIRGLLDYDTAKIGQINLALYHFSDSIQPVLRRLDIKPHWMFALSNLITSAV 3684
M I ++ LD+D++ I QI+L L+ F D++ +LR I+PHWMFA+ N+I AV
Sbjct: 960 RVMATTISKLKVDLDFDSSSISQIHLVLFGFQDAVNKILRNHLIRPHWMFAMDNIIRRAV 1019
Query: 3685 QCA 3693
Q A
Sbjct: 1020 QAA 1022
Score = 45.1 bits (105), Expect = 0.015
Identities = 20/60 (33%), Positives = 35/60 (58%)
Frame = +1
Query: 3922 VSWLRGLEIDERSIALIASEAYTKSDMMDFVTRDELLSIGVGGGSSCRIMRAIGEVRERQ 4101
+ WLR D ++I I E YT SD+++ +T+++L + + GG CR+ A+ + R Q
Sbjct: 1140 IDWLRLQGADAKTIEKIVEEGYTLSDILNEITKEDLRYLRLRGGLLCRLWSAVSQYRRAQ 1199
>gi|5174547|ref|NP_005914.1| mitogen-activated protein kinase kinase
kinase 5; apoptosis signal regulating kinase; MAP/ERK
kinase kinase 5; MAPK/ERK kinase kinase 5 [Homo sapiens]
gi|6685617|sp|Q99683|M3K5_HUMAN Mitogen-activated protein kinase
kinase kinase 5 (MAPK/ERK kinase kinase 5) (MEK kinase 5)
(MEKK 5) (Apoptosis signal-regulating kinase 1) (ASK-1)
gi|1679668|gb|AAC50894.1| mitogen-activated kinase kinase kinase 5
[Homo sapiens]
gi|32452016|gb|AAH54503.1| Mitogen-activated protein kinase kinase
kinase 5 [Homo sapiens]
Length = 1374
Score = 713 bits (1840), Expect = 0.0
Identities = 399/904 (44%), Positives = 559/904 (61%), Gaps = 19/904 (2%)
Frame = +1
Query: 121 AATSSSTNGSFEKSAIPGNARKLHVVIVIDQKVQKNLRVREM-ALKDVQKVADTLNVNLT 297
AATSSS+ S++ G +R+ V VI++ Q L V E AL+ +++ +T+ L
Sbjct: 69 AATSSSSATRGRGSSVGGGSRRTTVAYVINEASQGQLVVAESEALQSLREACETVGATLE 128
Query: 298 RIDFDKLDFGETETLDLFYNADVALVDVTVTHQQPSLCYHIGVRESMGQSYNMILTYWSP 477
+ F KLDFGET LD FYNAD+A+V+++ +QPSL YH+GVRES + N+IL
Sbjct: 129 TLHFGKLDFGETTVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYC--- 185
Query: 478 DPEYHIMDALKK-----------THAHLPMIVYIHHQDSNQLQSYDKXXXXXXSKPPFAR 624
D + +LK+ + +P ++ H++ S+ K +P F
Sbjct: 186 DTNSDSLQSLKEIICQKNTMCTGNYTFVPYMITPHNKVYCCDSSFMKGLTELM-QPNFEL 244
Query: 625 TNVPAKTITFQHRMKQVLKSVQVEASAHSREKFMSDLRKAREITDGDQKNDYLDKMRTRL 804
P + R Q+LK Q +S + RE ++D+RKAR + G + L ++R R+
Sbjct: 245 LLGPI-CLPLVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARIRQRV 303
Query: 805 DNPDVLHPDTVSLMMLSYRDNQNYGGMIRLVDDLKRIPDCLKVVDTPVIRYQYAFALNRR 984
DN +VL D V ++LSYRD Q+Y +++LV+ L+++P + +++ YAFALNRR
Sbjct: 304 DNIEVLTADIVINLLLSYRDIQDYDSIVKLVETLEKLPT-FDLASHHHVKFHYAFALNRR 362
Query: 985 NKDGDRDLALNTVLSLVEGTTENEEKNGPLSPDVVCLAGRIYKDKFIASNYEDRESLNSA 1164
N GDR AL+ ++ +V+ G ++ D+ CL GRIYKD F+ SN+ D ES +
Sbjct: 363 NLPGDRAKALDIMIPMVQS-------EGQVASDMYCLVGRIYKDMFLDSNFTDTESRDHG 415
Query: 1165 IEWYRRAFEMSPLEYSGINLTTLLRASGEHFENNLEMQQIAVVLNSLLGRKGALQNLMEY 1344
W+++AFE P SGIN LL A+G FE++ E++++ V L+SLLG+KG L+ L Y
Sbjct: 416 ASWFKKAFESEPTLQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSY 475
Query: 1345 WDVATYFEVSVLAENYQKACEAALMMVKLKPPVWYLKSTMENIKLINRCAATISPIEKEK 1524
W+V + SVLA ++ + +A+ + KLK P WYLKS +E I + + K
Sbjct: 476 WEVGFFLGASVLANDHMRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTTEQPVAK 535
Query: 1525 QQFL-FWSEFFMEATEADTDISCPRYPVLILELNKEFTPSYLTLNNE--EGTVILSHVLE 1695
Q+ + FW +F +EAT+ TD++ R+PVLILE K + PSYL++NNE E T+ + HVL
Sbjct: 536 QELVDFWMDFLVEATK--TDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLP 593
Query: 1696 NSQQKKIHQSELRGIHRWHFARNNIKAVTESKRDDRQLFLYVHENSDDFNLLFPTKAHCK 1875
+ + +GIH W+F+ ++++ V+ SK ++R FLYV NSDDF + F T+ HCK
Sbjct: 594 DDK---------KGIHEWNFSASSVRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCK 644
Query: 1876 KAYDDMKSMADVADGNYQGRVLSNPDNEK--IRFEYELSNSNERVVLGKGTYGTVYAARD 2049
K ++ + ++ + +GR D E + ++YE + +RVVLGKGTYG VYA RD
Sbjct: 645 KFFEMVNTITEE-----KGRSTEEGDCESDLLEYDYEYDENGDRVVLGKGTYGIVYAGRD 699
Query: 2050 MDTQRQIVVKEIEVKYDEEVQPLMEEISLHSTLCHANIVQYLGCDLVGKDGSNDHFLIFM 2229
+ Q +I +KEI + QPL EEI+LH L H NIVQYLG N IFM
Sbjct: 700 LSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLG-----SFSENGFIKIFM 754
Query: 2230 EHVPGGSLSSLLRSKWGPM--NENAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLVNTY 2403
E VPGGSLS+LLRSKWGP+ NE + +Y KQILEGLKYLH+ +IVHRDIKGDNVL+NTY
Sbjct: 755 EQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTY 814
Query: 2404 SGVCKISDFGTCKRLAGLNPVTETFTGTLQYMAPEVIDHGQRGYGAPADIWSFGCTMVEM 2583
SGV KISDFGT KRLAG+NP TETFTGTLQYMAPE+ID G RGYG ADIWS GCT++EM
Sbjct: 815 SGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEM 874
Query: 2584 ATGRPPFVEMQNPQAAMFRVGMFKTHPPIPTEITEKCRNFIKSCFLPEACDRPSAKDLLQ 2763
ATG+PPF E+ PQAAMF+VGMFK HP IP ++ + + FI CF P+ R A DLL
Sbjct: 875 ATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLV 934
Query: 2764 DPFI 2775
D F+
Sbjct: 935 DEFL 938
Score = 80.5 bits (197), Expect = 3e-13
Identities = 43/127 (33%), Positives = 75/127 (58%)
Frame = +1
Query: 3313 FFMLQKDSERRRSLGQFMQDYKDLIIDSWSTLLIKQSDTELVVTVYMLEMLLDGMRDFLL 3492
FFML+KDSERR +L + + + +D I+ + L + ++ + + + L+ +R+F+
Sbjct: 1041 FFMLRKDSERRATLHRILTEDQDKIVRNLMESLAQGAEEPKLKWEH-ITTLIASLREFVR 1099
Query: 3493 KKDNTKMQKMIDDIRGLLDYDTAKIGQINLALYHFSDSIQPVLRRLDIKPHWMFALSNLI 3672
D + + ++ LD+D+ I Q+ + L+ F D++ VLR +IKPHWMFAL ++I
Sbjct: 1100 STDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIKPHWMFALDSII 1159
Query: 3673 TSAVQCA 3693
AVQ A
Sbjct: 1160 RKAVQTA 1166
Score = 44.3 bits (103), Expect = 0.025
Identities = 22/58 (37%), Positives = 35/58 (59%)
Frame = +1
Query: 3928 WLRGLEIDERSIALIASEAYTKSDMMDFVTRDELLSIGVGGGSSCRIMRAIGEVRERQ 4101
WLR DE +I+ +E YT D++ +VTRD+L + + GG C + +AI + R +Q
Sbjct: 1316 WLRVNGADEDTISRFLAEDYTLLDVLYYVTRDDLKCLRLRGGMLCTLWKAIIDFRNKQ 1373
>gi|1805500|dbj|BAA12684.1| ASK1 [Homo sapiens]
Length = 1375
Score = 711 bits (1834), Expect = 0.0
Identities = 398/904 (44%), Positives = 558/904 (61%), Gaps = 19/904 (2%)
Frame = +1
Query: 121 AATSSSTNGSFEKSAIPGNARKLHVVIVIDQKVQKNLRVREM-ALKDVQKVADTLNVNLT 297
AATSSS+ S++ G +R+ V VI++ Q L V E AL+ +++ +T+ L
Sbjct: 69 AATSSSSATRGRGSSVGGGSRRTTVAYVINEASQGQLVVAESEALQSLREACETVGATLE 128
Query: 298 RIDFDKLDFGETETLDLFYNADVALVDVTVTHQQPSLCYHIGVRESMGQSYNMILTYWSP 477
+ F KLDFGET LD FYNAD+A+V+++ +QPSL YH+GVRES + N+IL
Sbjct: 129 TLHFGKLDFGETTVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYC--- 185
Query: 478 DPEYHIMDALKK-----------THAHLPMIVYIHHQDSNQLQSYDKXXXXXXSKPPFAR 624
D + +LK+ + +P ++ H++ S+ K +P F
Sbjct: 186 DTNSDSLQSLKEIICQKNTMCTGNYTFVPYMITPHNKVYCCDSSFMKGLTELM-QPNFEL 244
Query: 625 TNVPAKTITFQHRMKQVLKSVQVEASAHSREKFMSDLRKAREITDGDQKNDYLDKMRTRL 804
P + R Q+LK Q +S + RE ++D+RKAR + G + L ++R R+
Sbjct: 245 LLGPI-CLPLVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARIRQRV 303
Query: 805 DNPDVLHPDTVSLMMLSYRDNQNYGGMIRLVDDLKRIPDCLKVVDTPVIRYQYAFALNRR 984
DN +VL D V ++LSYRD Q+Y +++LV+ L+++P + +++ YAFALNRR
Sbjct: 304 DNIEVLTADIVINLLLSYRDIQDYDSIVKLVETLEKLPT-FDLASHHHVKFHYAFALNRR 362
Query: 985 NKDGDRDLALNTVLSLVEGTTENEEKNGPLSPDVVCLAGRIYKDKFIASNYEDRESLNSA 1164
N GDR AL+ ++ +V+ G ++ D+ CL GRIYKD F+ SN+ D ES +
Sbjct: 363 NLPGDRAKALDIMIPMVQS-------EGQVASDMYCLVGRIYKDMFLDSNFTDTESRDHG 415
Query: 1165 IEWYRRAFEMSPLEYSGINLTTLLRASGEHFENNLEMQQIAVVLNSLLGRKGALQNLMEY 1344
W+++AFE P SGIN LL A+G FE++ E++++ V L+SLLG+KG L+ L Y
Sbjct: 416 ASWFKKAFESEPTLQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSY 475
Query: 1345 WDVATYFEVSVLAENYQKACEAALMMVKLKPPVWYLKSTMENIKLINRCAATISPIEKEK 1524
W+V + SVLA ++ + +A+ + KLK P WYLKS +E I + + K
Sbjct: 476 WEVGFFLGASVLANDHMRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTTEQPVAK 535
Query: 1525 QQFL-FWSEFFMEATEADTDISCPRYPVLILELNKEFTPSYLTLNNE--EGTVILSHVLE 1695
Q+ + FW +F +EAT+ TD++ R+PVLILE K + PSYL++NNE E T+ + HVL
Sbjct: 536 QELVDFWMDFLVEATK--TDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLP 593
Query: 1696 NSQQKKIHQSELRGIHRWHFARNNIKAVTESKRDDRQLFLYVHENSDDFNLLFPTKAHCK 1875
+ + +GIH W+F+ ++++ V+ SK ++R FLYV NSDDF + F T+ HCK
Sbjct: 594 DDK---------KGIHEWNFSASSVRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCK 644
Query: 1876 KAYDDMKSMADVADGNYQGRVLSNPDNEK--IRFEYELSNSNERVVLGKGTYGTVYAARD 2049
K ++ + ++ + +GR D E + ++YE + +RVVLGKGTYG VYA RD
Sbjct: 645 KFFEMVNTITEE-----KGRSTEEGDCESDLLEYDYEYDENGDRVVLGKGTYGIVYAGRD 699
Query: 2050 MDTQRQIVVKEIEVKYDEEVQPLMEEISLHSTLCHANIVQYLGCDLVGKDGSNDHFLIFM 2229
+ Q +I +KEI + QPL EEI+LH L H NIVQYLG N IFM
Sbjct: 700 LSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLG-----SFSENGFIKIFM 754
Query: 2230 EHVPGGSLSSLLRSKWGPM--NENAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLVNTY 2403
E VPGGSL +LLRSKWGP+ NE + +Y KQILEGLKYLH+ +IVHRDIKGDNVL+NTY
Sbjct: 755 EQVPGGSLYALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTY 814
Query: 2404 SGVCKISDFGTCKRLAGLNPVTETFTGTLQYMAPEVIDHGQRGYGAPADIWSFGCTMVEM 2583
SGV KISDFGT KRLAG+NP TETFTGTLQYMAPE+ID G RGYG ADIWS GCT++EM
Sbjct: 815 SGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEM 874
Query: 2584 ATGRPPFVEMQNPQAAMFRVGMFKTHPPIPTEITEKCRNFIKSCFLPEACDRPSAKDLLQ 2763
ATG+PPF E+ PQAAMF+VGMFK HP IP ++ + + FI CF P+ R A DLL
Sbjct: 875 ATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLV 934
Query: 2764 DPFI 2775
D F+
Sbjct: 935 DEFL 938
Score = 80.5 bits (197), Expect = 3e-13
Identities = 43/127 (33%), Positives = 75/127 (58%)
Frame = +1
Query: 3313 FFMLQKDSERRRSLGQFMQDYKDLIIDSWSTLLIKQSDTELVVTVYMLEMLLDGMRDFLL 3492
FFML+KDSERR +L + + + +D I+ + L + ++ + + + L+ +R+F+
Sbjct: 1042 FFMLRKDSERRATLHRILTEDQDKIVRNLMESLAQGAEEPKLKWEH-ITTLIASLREFVR 1100
Query: 3493 KKDNTKMQKMIDDIRGLLDYDTAKIGQINLALYHFSDSIQPVLRRLDIKPHWMFALSNLI 3672
D + + ++ LD+D+ I Q+ + L+ F D++ VLR +IKPHWMFAL ++I
Sbjct: 1101 STDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIKPHWMFALDSII 1160
Query: 3673 TSAVQCA 3693
AVQ A
Sbjct: 1161 RKAVQTA 1167
Score = 44.3 bits (103), Expect = 0.025
Identities = 22/58 (37%), Positives = 35/58 (59%)
Frame = +1
Query: 3928 WLRGLEIDERSIALIASEAYTKSDMMDFVTRDELLSIGVGGGSSCRIMRAIGEVRERQ 4101
WLR DE +I+ +E YT D++ +VTRD+L + + GG C + +AI + R +Q
Sbjct: 1317 WLRVNGADEDTISRFLAEDYTLLDVLYYVTRDDLKCLRLRGGMLCTLWKAIIDFRNKQ 1374
>gi|6678796|ref|NP_032606.1| mitogen activated protein kinase kinase
kinase 5; MEK kinase 5 [Mus musculus]
gi|6685611|sp|O35099|M3K5_MOUSE Mitogen-activated protein kinase
kinase kinase 5 (MAPK/ERK kinase kinase 5) (MEK kinase 5)
(MEKK 5) (Apoptosis signal-regulating kinase 1) (ASK-1)
gi|7513598|pir||JC5778 apoptosis signal-regulating kinase (EC
2.7.-.-) 1 - mouse
gi|2653434|dbj|BAA23648.1| apoptosis signal-regulating kinase 1 [Mus
musculus]
Length = 1379
Score = 696 bits (1796), Expect = 0.0
Identities = 395/907 (43%), Positives = 555/907 (60%), Gaps = 22/907 (2%)
Frame = +1
Query: 121 AATSSSTNGSFEKSAIPGNARKLHVVIVIDQKVQKNLRVREM-ALKDVQKVADTLNVNLT 297
A SS+T G + G R+ V VI++ Q L V E AL+ ++ + + L
Sbjct: 78 APGSSATRGRGNSGS--GGGRRTTVAYVINEASQGQLVVAESEALQSWREACEAVGATLE 135
Query: 298 RIDFDKLDFGETETLDLFYNADVALVDVTVTHQQPSLCYHIGVRESMGQSYNMILTYWSP 477
+ F KLDFGET LD FYNAD+A+V+++ T +QPSL YH+GVRES + N+IL
Sbjct: 136 TLHFGKLDFGETAVLDRFYNADIAVVEMSDTFRQPSLFYHLGVRESFSMANNIILYC--- 192
Query: 478 DPEYHIMDALKK-----------THAHLPMIVYIHHQDSNQLQSYDKXXXXXXSKPPFAR 624
D + +LK+ + +P +V H++ S+ K +P F
Sbjct: 193 DTNSDSLQSLKEIICQKNTVCTGNYTFIPYMVTPHNKVYCCDSSFMKGLTELM-QPNFEL 251
Query: 625 TNVPAKTITFQHRMKQVLKSVQVEASAHSREKFMSDLRKAREITDGDQKNDYLDKMRTRL 804
P + R Q+LK Q +S + RE +SD+RKAR + G + L ++R R+
Sbjct: 252 LLGPI-CLPLVDRFVQLLKVAQRSSSQYFRESILSDIRKARNLYTGKELAAELARIRQRV 310
Query: 805 DNPDVLHPDTVSLMMLSYRDNQNYGGMIRLVDDLKRIPDCLKVVDTPVIRYQYAFALNRR 984
DN +VL D V ++LSYRD Q+Y +++LV+ L+++P + +++ YAFALN R
Sbjct: 311 DNIEVLTADIVINLLLSYRDIQDYDSIVKLVETLEKLPT-FDLASHHHVKFHYAFALNTR 369
Query: 985 NKDGDRDLALNTVLSLVEGTTENEEKNGPLSPDVVCLAGRIYKDKFIASNYEDRESLNSA 1164
GDR AL+ ++ +V+ +EE+ ++ D+ CL GRIYKD F+ SN+ D ES +
Sbjct: 370 TLPGDRAKALDIMIPMVQ----SEEQ---VASDMYCLVGRIYKDMFLDSNFTDTESRDHG 422
Query: 1165 IEWYRRAFEMSPLEYSGINLTTLLRASGEHFENNLEMQQIAVVLNSLLGRKGALQNLMEY 1344
W+++AFE P SGIN LL A+G FE++ E++++ V L+SLLG+KG L+ L Y
Sbjct: 423 ASWFKKAFESEPTLQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSY 482
Query: 1345 WDVATYFEVSVLAENYQKACEAALMMVKLKPPVWYLKSTMENIKLINRCAATISPIEKEK 1524
W+V + SVLA ++ + +A+ + +LK P WYLKS +E I + + K
Sbjct: 483 WEVGFFLGASVLANDHLRVIQASEKLFRLKTPAWYLKSIVETILIYKHFVKLTTEQPSAK 542
Query: 1525 QQFL-FWSEFFMEATEADTDISCPRYPVLILELNKEFTPSYLTLNNE--EGTVILSHVLE 1695
Q+ + FW +F +EAT+ TD++ R+PVLILE K + PSYL++NNE E T+ + HVL
Sbjct: 543 QELVDFWMDFLVEATK--TDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLP 600
Query: 1696 NSQQKKIHQSELRGIHRWHFARNNIKAVTESKRDDRQLFLYVHENSDDFNLLFPTKAHCK 1875
+ + +GIH W+F ++++ V+ SK ++R FLYV NSDDF + F T+ HCK
Sbjct: 601 DDK---------KGIHEWNFGASSVRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCK 651
Query: 1876 KAYDDMKSMAD-----VADGNYQGRVLSNPDNEKIRFEYELSNSNERVVLGKGTYGTVYA 2040
+ ++ + ++ + DG+ +G + + ++YE + +RVVLGKGTYG VYA
Sbjct: 652 RFFEMVNTITEEKGRGAEDGDCEG--------DSLEYDYEYDENGDRVVLGKGTYGIVYA 703
Query: 2041 ARDMDTQRQIVVKEIEVKYDEEVQPLMEEISLHSTLCHANIVQYLGCDLVGKDGSNDHFL 2220
RD+ Q +I +KEI + QPL EEI+LH L H NIVQYLG N
Sbjct: 704 GRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLG-----SFSENCFIK 758
Query: 2221 IFMEHVPGGSLSSLLRSKWGPM--NENAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLV 2394
IFME VPGGSLS+LLRSKWGP+ NE + +Y KQILEGLKYLH+ +IVHRDIKGDNVL+
Sbjct: 759 IFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLI 818
Query: 2395 NTYSGVCKISDFGTCKRLAGLNPVTETFTGTLQYMAPEVIDHGQRGYGAPADIWSFGCTM 2574
NTYSGV KISDFGT KRLAG+NP TETFTGTLQYMAPE+ID G RGYG ADIWS GCT+
Sbjct: 819 NTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTI 878
Query: 2575 VEMATGRPPFVEMQNPQAAMFRVGMFKTHPPIPTEITEKCRNFIKSCFLPEACDRPSAKD 2754
+EMATG+PPF E+ PQAAMF+VGMFK HP IP ++ + + FI CF P+ R A D
Sbjct: 879 IEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACAND 938
Query: 2755 LLQDPFI 2775
LL D F+
Sbjct: 939 LLIDEFL 945
Score = 81.3 bits (199), Expect = 2e-13
Identities = 43/127 (33%), Positives = 75/127 (58%)
Frame = +1
Query: 3313 FFMLQKDSERRRSLGQFMQDYKDLIIDSWSTLLIKQSDTELVVTVYMLEMLLDGMRDFLL 3492
FFML+KDSERR +L + + + +D ++ + L + ++ E + + L+ +R+F+
Sbjct: 1048 FFMLRKDSERRATLHRILTEDQDKVVRNLMESLAQGAE-EPKLNWEHITTLISSLREFVR 1106
Query: 3493 KKDNTKMQKMIDDIRGLLDYDTAKIGQINLALYHFSDSIQPVLRRLDIKPHWMFALSNLI 3672
D + + ++ LD+D+ I Q+ + L+ F D++ VLR +IKPHWMFAL ++I
Sbjct: 1107 STDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIKPHWMFALDSII 1166
Query: 3673 TSAVQCA 3693
AVQ A
Sbjct: 1167 RKAVQTA 1173
Score = 42.7 bits (99), Expect = 0.073
Identities = 21/57 (36%), Positives = 34/57 (58%)
Frame = +1
Query: 3928 WLRGLEIDERSIALIASEAYTKSDMMDFVTRDELLSIGVGGGSSCRIMRAIGEVRER 4098
WLR DE +I+ +E YT D++ +VTRD+L + + GG C + +AI + R +
Sbjct: 1322 WLRENGADEDTISRFLAEDYTLVDVLYYVTRDDLKCLRLRGGMLCTLWKAIIDFRNK 1378
>gi|45553423|ref|NP_996240.1| CG4720-PB [Drosophila melanogaster]
gi|45446549|gb|AAS65178.1| CG4720-PB [Drosophila melanogaster]
Length = 1196
Score = 689 bits (1779), Expect = 0.0
Identities = 375/701 (53%), Positives = 474/701 (67%), Gaps = 13/701 (1%)
Frame = +1
Query: 712 REKFMSDLRKAREI--TDGDQKNDYLDKMRTRLDNPDVLHPDTVSLMMLSYRDNQNYGGM 885
REKF+SD+R AR+ T+G + L +MR RLD+P VL + V M S RD Q+Y M
Sbjct: 2 REKFLSDMRTARDTYATNGAKLQSILHEMRKRLDDPHVLSGEVVHSFMCSLRDVQDYDAM 61
Query: 886 IRLVDDLKRIPDCLKVVDTPVIRYQYAFALNRRNKDGDRDLALNTVLSLVEGTTENEEKN 1065
+RLV+DLK IP+ K V+T + + YAFALNRRN+ GDR+ AL + L +E K
Sbjct: 62 VRLVNDLKNIPNTRKYVETGNMSFLYAFALNRRNRKGDREKALESSLKALE-------KK 114
Query: 1066 GPLSPDVVCLAGRIYKDKFIASNYEDRESLNSAIEWYRRAFEMSPLEYSGINLTTLLRAS 1245
PD++CL GRIYKD F+ S+Y D SL AI+WYR++FE+ P EY+GINL TLL
Sbjct: 115 ENHFPDMLCLCGRIYKDIFVESDYTDATSLAHAIKWYRQSFEVQPNEYAGINLATLLVIE 174
Query: 1246 GEHFENNLEMQQIAVVLNSLLGRKGALQNLMEYWDVATYFEVSVLAENYQKACEAALMMV 1425
G+ F N E+Q I + LN+L+G+KG+L +L EYWDVAT+FE+SVLA +Y KA +AA M
Sbjct: 175 GKEFTNTEELQHIGMTLNNLIGKKGSLSSLSEYWDVATFFEISVLANDYAKAIQAAECMF 234
Query: 1426 KLKPPVWYLKSTMENIKLINRCAATISPIEK----EKQQFLFWSEFFMEATEADTDISCP 1593
KLKPP WYLKST+ NI LI+R P E+ E+Q F FW +FF+EAT + +
Sbjct: 235 KLKPPNWYLKSTIGNISLIHRFRK--KPEERQPPIEEQVFQFWMDFFLEATNTEEVKNSI 292
Query: 1594 RYPVLILELNKEFTPSYLTLN---NEEGTVILSHVLENSQQKKIHQSELRGIHRWHFARN 1764
R+P+LILE K + PSY+T+N +E+ I++ L +++ + + IH + F +
Sbjct: 293 RFPILILEPQKIYMPSYVTINMDADEKSIQIVNICLAHAK------NACKKIHDFLFVAS 346
Query: 1765 NIKAVTESKRDDRQLFLYVHENSDDFNLLFPTKAHCKKAYDDMKSMA--DVADGNYQGRV 1938
IK+V+ KRDDR +LYVH NSDDF + FP+ +K YD + M V N
Sbjct: 347 KIKSVSLYKRDDRCAYLYVHHNSDDFQIYFPSTERRQKFYDMILEMTADQVVFVN----- 401
Query: 1939 LSNPDNEKIRFEYELSNSNERVVLGKGTYGTVYAARDMDTQRQIVVKEIEVKYDEEVQPL 2118
LSN D+ I +EY+ N ++VLGKGTYGTVYAARD TQ +I +KE+ K ++VQPL
Sbjct: 402 LSN-DDANIEYEYDYDEQNRKMVLGKGTYGTVYAARDKQTQVRIAIKEVPEKNSQDVQPL 460
Query: 2119 MEEISLHSTLCHANIVQYLGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLRSKWGPM--NE 2292
EEI LHS L H NIV+YLG N F IFME VPGGSLS LL +KWGP+ NE
Sbjct: 461 HEEIKLHSQLRHRNIVRYLG-----SCSENGFFKIFMEQVPGGSLSDLLETKWGPLKDNE 515
Query: 2293 NAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVTE 2472
+ M +Y KQILEGLKYLHE IVHRDIKGDNVLVNTYSGV KISDFGT KRLA +NP+TE
Sbjct: 516 STMAFYSKQILEGLKYLHEQDIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLARINPMTE 575
Query: 2473 TFTGTLQYMAPEVIDHGQRGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQAAMFRVGMF 2652
TFTGTLQYMAPEVID G RGYG ADIWSFGCT VEMATG+PPF+E+ + AAMF+VG +
Sbjct: 576 TFTGTLQYMAPEVIDQGVRGYGPAADIWSFGCTNVEMATGKPPFIELGSAHAAMFKVGFY 635
Query: 2653 KTHPPIPTEITEKCRNFIKSCFLPEACDRPSAKDLLQDPFI 2775
K HP IP E++ +NFI CF DRPSA LL+DPF+
Sbjct: 636 KKHPNIPEELSANAKNFILRCFAISVMDRPSASQLLEDPFL 676
Score = 87.0 bits (214), Expect = 3e-15
Identities = 46/130 (35%), Positives = 79/130 (60%), Gaps = 3/130 (2%)
Frame = +1
Query: 3313 FFMLQKDSERRRSLGQFMQDYKDLIIDSWSTLLIKQSDTE---LVVTVYMLEMLLDGMRD 3483
F+ L+KDS+RR +L + + + I D W +K+ D + + + LE+L+ G+RD
Sbjct: 780 FYRLKKDSQRRTTLSKVLALDESKICDIW----LKKVDADQNSIAIRKSDLEVLIRGLRD 835
Query: 3484 FLLKKDNTKMQKMIDDIRGLLDYDTAKIGQINLALYHFSDSIQPVLRRLDIKPHWMFALS 3663
+++ ++ ++ I++++ L+ D + ++LALY F D++ VLR IKPHWMFAL
Sbjct: 836 YIMNENEKHLEATINELKQKLNNDAVALDHLHLALYSFQDAVVCVLRYHCIKPHWMFALD 895
Query: 3664 NLITSAVQCA 3693
NL+ AVQ A
Sbjct: 896 NLVKRAVQAA 905
>gi|50730209|ref|XP_416808.1| PREDICTED: similar to mitogen-activated
protein kinase kinase kinase 5; apoptosis signal
regulating kinase; MAP/ERK kinase kinase 5; MAPK/ERK
kinase kinase 5 [Gallus gallus]
Length = 1452
Score = 674 bits (1739), Expect = 0.0
Identities = 357/728 (49%), Positives = 483/728 (66%), Gaps = 3/728 (0%)
Frame = +1
Query: 661 RMKQVLKSVQVEASAHSREKFMSDLRKAREITDGDQKNDYLDKMRTRLDNPDVLHPDTVS 840
R +LK V V + A+ +E ++D+RKARE GD+ L +++ R+DN +VL D V
Sbjct: 350 RFISLLKDVHVTSCAYYKETLLNDIRKAREKYQGDELAKELARIKLRMDNTEVLTSDIVI 409
Query: 841 LMMLSYRDNQNYGGMIRLVDDLKRIPDCLKVVDTPVIRYQYAFALNRRNKDGDRDLALNT 1020
++LSYRD Q+Y M++LV+ L+ +P C + D I++ YAFALNRRN GDR+ AL
Sbjct: 410 NLLLSYRDIQDYDAMVKLVETLEMLPTC-DLADQHNIKFHYAFALNRRNNAGDREKALQV 468
Query: 1021 VLSLVEGTTENEEKNGPLSPDVVCLAGRIYKDKFIASNYEDRESLNSAIEWYRRAFEMSP 1200
+L +++ T ++ +PD+ CL GRIYKD F+ S+ +D S + AIEWYR+ FE+
Sbjct: 469 MLQVLQ-TCDHP------APDMFCLCGRIYKDMFLDSDCKDINSRDHAIEWYRKGFELQS 521
Query: 1201 LEYSGINLTTLLRASGEHFENNLEMQQIAVVLNSLLGRKGALQNLMEYWDVATYFEVSVL 1380
YSGINL LL A G+ FE+++E+++I V LNSLLGRKG+L+ + YWDV +F VS+L
Sbjct: 522 TLYSGINLAVLLLAEGQQFESSMELRKIGVRLNSLLGRKGSLEKMNSYWDVGQFFSVSML 581
Query: 1381 AENYQKACEAALMMVKLKPPVWYLKSTMENIKLINRCAATISPIEKEKQQFLFWSEFFME 1560
A + KA +AA + KLKPPVWYLKS ++N+ LI R ++++ FW + E
Sbjct: 582 ANDVSKAVQAAEKLFKLKPPVWYLKSLVQNLMLIQRFKKFTIEHSPKQERLTFWLDIIFE 641
Query: 1561 ATEADTDISCPRYPVLILELNKEFTPSYLTLNNEEGTVILSHVLENSQQKKIHQSELRGI 1740
AT+ T+ R+PVL++E K + P+Y+++NNEE LS + +E++ I
Sbjct: 642 ATKETTNGL--RFPVLVIEPTKVYQPAYVSINNEEDERSLS-------LWHVSPTEMKQI 692
Query: 1741 HRWHFARNNIKAVTESKRDDRQLFLYVHENSDDFNLLFPTKAHCKKAYDDMKSMADVADG 1920
H W+F ++I+ ++ SK D+R FLYVH NSDDF + F T+ C + +K + A G
Sbjct: 693 HEWNFTASSIRGISISKFDERCCFLYVHANSDDFQIYFSTENQCTRFCGLVKEILSDAVG 752
Query: 1921 N---YQGRVLSNPDNEKIRFEYELSNSNERVVLGKGTYGTVYAARDMDTQRQIVVKEIEV 2091
+ +G + D E + +EY+ +RVVLGKGTYG VYA RD+ Q +I +KEI
Sbjct: 753 STLELEGEI----DGETLEYEYDYDEKGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPE 808
Query: 2092 KYDEEVQPLMEEISLHSTLCHANIVQYLGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLRS 2271
+ QPL EEI+LH L H N+VQYLG V +DG + IFME VPGGSLS+LLRS
Sbjct: 809 RDSRYSQPLHEEIALHKYLKHRNVVQYLGS--VSEDG---YIKIFMEQVPGGSLSALLRS 863
Query: 2272 KWGPMNENAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLA 2451
KWGPM E + +Y KQILEGLKYLHE +IVHRDIKGDNVLVNTYSGV KISDFGT KRLA
Sbjct: 864 KWGPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLA 923
Query: 2452 GLNPVTETFTGTLQYMAPEVIDHGQRGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQAA 2631
G+NP TETFTGTLQYMAPE+ID G RGYGAPADIWS GCTM+EMATG+PPF E+ PQAA
Sbjct: 924 GINPCTETFTGTLQYMAPEIIDKGPRGYGAPADIWSLGCTMIEMATGKPPFHELGEPQAA 983
Query: 2632 MFRVGMFKTHPPIPTEITEKCRNFIKSCFLPEACDRPSAKDLLQDPFIYHNHHSISRTRS 2811
MF+VGMFK HP IP ++ + + FI CF P+ R +A DLL+D F+ +++ +
Sbjct: 984 MFKVGMFKIHPEIPESLSAEAKAFILLCFEPDPFKRAAASDLLRDSFL----KQVNKGKK 1039
Query: 2812 GSINKKPA 2835
I KP+
Sbjct: 1040 SRIAFKPS 1047
Score = 85.5 bits (210), Expect = 1e-14
Identities = 45/126 (35%), Positives = 77/126 (60%)
Frame = +1
Query: 3316 FMLQKDSERRRSLGQFMQDYKDLIIDSWSTLLIKQSDTELVVTVYMLEMLLDGMRDFLLK 3495
F+L+KDSERR L + +++ ++ + + I QS EL +++ ++ ++ +RDF+
Sbjct: 1132 FLLRKDSERRAILYKILKEEQNKVASNLQDC-IAQSSEELRLSMAHIKQIIGILRDFIHS 1190
Query: 3496 KDNTKMQKMIDDIRGLLDYDTAKIGQINLALYHFSDSIQPVLRRLDIKPHWMFALSNLIT 3675
++ M I ++ LD+D+ I QI+L L+ F D++ VLR I+PHWMFA+ N+I
Sbjct: 1191 PEHRVMASTISKLKMDLDFDSTSINQIHLVLFGFQDAVNKVLRNHLIRPHWMFAMDNIIR 1250
Query: 3676 SAVQCA 3693
AVQ A
Sbjct: 1251 RAVQAA 1256
Score = 39.3 bits (90), Expect = 0.80
Identities = 22/47 (46%), Positives = 29/47 (60%)
Frame = +1
Query: 364 VALVDVTVTHQQPSLCYHIGVRESMGQSYNMILTYWSPDPEYHIMDA 504
VA+VD++ +QPSL YH+GVRES + N+IL YH DA
Sbjct: 195 VAVVDMSDISKQPSLFYHLGVRESFDMANNVIL--------YHGTDA 233
>gi|47221132|emb|CAG05453.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 1408
Score = 669 bits (1726), Expect = 0.0
Identities = 346/721 (47%), Positives = 474/721 (64%), Gaps = 13/721 (1%)
Frame = +1
Query: 661 RMKQVLKSVQVEASAHSREKFMSDLRKAREITDGDQKNDYLDKMRTRLDNPDVLHPDTVS 840
R +LK + V + A ++ ++D+RKARE G++ L +++ R+DN +VL D V
Sbjct: 278 RFTSLLKDIHVTSCASFKDTLLNDIRKAREKYQGEELAKELSRIKLRIDNTEVLTQDIVM 337
Query: 841 LMMLSYRDNQNYGGMIRLVDDLKRIPDCLKVVDTPVIRYQYAFALNRRNKDGDRDLALNT 1020
++ SYRD Q+Y M++LV L+ +P C + P+I++ +AFALNRRN GDR+ AL
Sbjct: 338 NLLFSYRDIQDYDAMVKLVQTLEMLPTC-DLATQPMIQFHFAFALNRRNSPGDREQALRV 396
Query: 1021 VLSLVEGTTENEEKNGPLSPDVVCLAGRIYKDKFIASNYEDRESLNSAIEWYRRAFEMSP 1200
+L +++ +PD+ CL GRIYKD F+ S+ +D + ++AI WYR+ FE+ P
Sbjct: 397 MLQVLQSCEHP-------APDMFCLCGRIYKDIFLDSDCKDTRNRDNAIHWYRKGFELQP 449
Query: 1201 LEYSGINLTTLLRASGEHFENNLEMQQIAVVLNSLLGRKGALQNLMEYWDVATYFEVSVL 1380
YSGINLT LL +G+ FEN++E+++I V LNSLLGRKG+L+ + YWDV +F VS+L
Sbjct: 450 TLYSGINLTVLLIVAGQQFENSMELRKIGVRLNSLLGRKGSLEKMNNYWDVGQFFTVSML 509
Query: 1381 AENYQKACEAALMMVKLKPPVWYLKSTMENIKLINRCAATISPIEKEKQQFLFWSEFFME 1560
A + KA +AA + KLKPP+WYL+S ++N++LI R I ++++ FW + +E
Sbjct: 510 ANDVPKATQAAEKLFKLKPPLWYLRSVVQNLQLIQRFKKQIVDHSPQRERLNFWMDIIVE 569
Query: 1561 ATEADTDISCPRYPV-----------LILELNKEFTPSYLTLNNE--EGTVILSHVLENS 1701
AT+ T+ R+PV LILE K + PSY+++NNE E V + HV
Sbjct: 570 ATQGTTNRL--RFPVRNHPQPVETLVLILEPTKVYQPSYVSINNEDEEKNVSIWHV---- 623
Query: 1702 QQKKIHQSELRGIHRWHFARNNIKAVTESKRDDRQLFLYVHENSDDFNLLFPTKAHCKKA 1881
+E +GIH W+F +IK ++ SK D+R FLYVH+NSDDF + F T+ C +
Sbjct: 624 -----SPAETKGIHEWNFTAMSIKGISISKFDERCCFLYVHDNSDDFQIYFSTEEQCGRF 678
Query: 1882 YDDMKSMADVADGNYQGRVLSNPDNEKIRFEYELSNSNERVVLGKGTYGTVYAARDMDTQ 2061
+K M GN + D + + +EY+ + + +RVVLG+GTYG VYA RD+ Q
Sbjct: 679 CSTVKEMISDGTGN-SVELEGEGDGDTLEYEYDTNETGDRVVLGRGTYGVVYAGRDLSNQ 737
Query: 2062 RQIVVKEIEVKYDEEVQPLMEEISLHSTLCHANIVQYLGCDLVGKDGSNDHFLIFMEHVP 2241
+I +KEI + QPL EEI+LH L H NIVQYLG N + IFME VP
Sbjct: 738 VRIAIKEIPERDSRYSQPLHEEIALHKYLKHRNIVQYLG-----SVSENGYIKIFMEQVP 792
Query: 2242 GGSLSSLLRSKWGPMNENAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLVNTYSGVCKI 2421
GGSLS+LLRSKWGP+ E + +Y +QILEGL+YLH+ +IVHRDIKGDNVLVNTYSGV KI
Sbjct: 793 GGSLSALLRSKWGPLKEATIIFYTRQILEGLRYLHDNQIVHRDIKGDNVLVNTYSGVLKI 852
Query: 2422 SDFGTCKRLAGLNPVTETFTGTLQYMAPEVIDHGQRGYGAPADIWSFGCTMVEMATGRPP 2601
SDFGT KRLAG+NP TETFTGTLQYMAPE+ID G RGYGAPADIWS GCT++EMATG+PP
Sbjct: 853 SDFGTSKRLAGVNPCTETFTGTLQYMAPEIIDKGPRGYGAPADIWSLGCTIIEMATGKPP 912
Query: 2602 FVEMQNPQAAMFRVGMFKTHPPIPTEITEKCRNFIKSCFLPEACDRPSAKDLLQDPFIYH 2781
F E+ PQAAMF+VGMFK HP IP ++ + ++FI CF P+ R A DLL+D F+ H
Sbjct: 913 FHELGEPQAAMFKVGMFKIHPEIPESLSLEAKSFILRCFEPDPLKRAIATDLLRDTFVRH 972
Query: 2782 N 2784
+
Sbjct: 973 H 973
Score = 84.0 bits (206), Expect = 3e-14
Identities = 51/161 (31%), Positives = 84/161 (51%)
Frame = +1
Query: 3211 IVSPISLNTMGSPLSSAALLNRTIXXXXXXXXXRFFMLQKDSERRRSLGQFMQDYKDLII 3390
++ P + N + P + +R FML+KDSERR L + + + + +I
Sbjct: 1034 LLKPPNSNYLSVPDEGSVSEDRIAPPSPEDRDSGLFMLKKDSERRAILFKVLNEDQAKVI 1093
Query: 3391 DSWSTLLIKQSDTELVVTVYMLEMLLDGMRDFLLKKDNTKMQKMIDDIRGLLDYDTAKIG 3570
+ I+ S+ L +++ ++ ++ +RDF+ + M I ++ LD+D+ I
Sbjct: 1094 SNLRENYIQGSEA-LQLSLEHIKQIICILRDFIHSPERRVMAATISKLKLDLDFDSTSIN 1152
Query: 3571 QINLALYHFSDSIQPVLRRLDIKPHWMFALSNLITSAVQCA 3693
QI L L+ F DS+ VLR IKPHWMFA+ N+I AVQ A
Sbjct: 1153 QIQLVLFGFQDSVNKVLRNHHIKPHWMFAMDNIIRRAVQAA 1193
Score = 81.3 bits (199), Expect = 2e-13
Identities = 45/108 (41%), Positives = 66/108 (60%), Gaps = 2/108 (1%)
Frame = +1
Query: 169 PGNARKLHVVIVIDQKVQKNLRV--REMALKDVQKVADTLNVNLTRIDFDKLDFGETETL 342
P R L VV V++ ++ + AL+ +Q+ D + LT + F +LDFGET L
Sbjct: 36 PTKQRSLRVVYVLNDGLKSVMASSPESGALQCLQRACDAESALLTTVTFGRLDFGETSVL 95
Query: 343 DLFYNADVALVDVTVTHQQPSLCYHIGVRESMGQSYNMILTYWSPDPE 486
D FY+AD+A+VD++ +QPSL YH+GVRES + N+IL Y DP+
Sbjct: 96 DSFYDADIAVVDMSDVFRQPSLFYHLGVRESFDMANNVIL-YHDTDPD 142
Score = 41.2 bits (95), Expect = 0.21
Identities = 22/58 (37%), Positives = 32/58 (54%)
Frame = +1
Query: 3928 WLRGLEIDERSIALIASEAYTKSDMMDFVTRDELLSIGVGGGSSCRIMRAIGEVRERQ 4101
WL D +I E Y SD++D +++++L + + GG CRI RAI RERQ
Sbjct: 1351 WLEEQGADADTIDKFVLEDYKLSDVLDDISKEDLRCLCLRGGVLCRIWRAIQRHRERQ 1408
>gi|50742707|ref|XP_419725.1| PREDICTED: similar to mitogen-activated
protein kinase kinase kinase 5; apoptosis signal
regulating kinase; MAP/ERK kinase kinase 5; MAPK/ERK
kinase kinase 5 [Gallus gallus]
Length = 1300
Score = 640 bits (1650), Expect = 0.0
Identities = 362/843 (42%), Positives = 508/843 (59%), Gaps = 38/843 (4%)
Frame = +1
Query: 361 DVALVDVTVTHQQPSLCYHIGVRESMGQSYNMILTYWSPDPEYHIMDALKKTHAHLPMIV 540
D+A+V+++ +QPSL YH+GVRES + N+IL + + + +P ++
Sbjct: 36 DIAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDTNSESLQSLKMCTGNYIFVPYMI 95
Query: 541 YIHHQDSNQLQSYDKXXXXXXSKPPFARTNVPAKTITFQHRMKQVLKSVQVEASAHSREK 720
H++ S+ K +P F P + R Q+LK Q +S + RE
Sbjct: 96 TPHNKVYCCDSSFMKGLTELM-QPSFESLLGPI-CLPLVDRFIQLLKVAQASSSQYFRES 153
Query: 721 FMSDLRKAREITDGDQKNDYLDKMRTRLDNPDVLHPDTVSLMMLSYRDNQNYGGMIRLVD 900
++D+RKAR + G + L ++R R+DN +VL D V ++LSYRD Q+Y +++LV
Sbjct: 154 ILNDIRKARTLYTGKELAAELARIRQRVDNIEVLSADIVINLLLSYRDIQDYDSIVKLVK 213
Query: 901 DLKRIPDCLKVVDTPVIRYQYAFALNRRNKDGDRDLALNTVLSLVEGTTENEEKNGPLSP 1080
L+++P + +R YAFALNRRN GDR AL ++ LVE + ++
Sbjct: 214 TLEKLPT-FDLASHHHVRLHYAFALNRRNLPGDRQKALEIMIPLVE-------QEDQVAS 265
Query: 1081 DVVCLAGRIYKDKFIASNYEDRESLNSAIEWYRRAFEMSPLEYSGINLTTLLRASGEHFE 1260
D+ CL GRIYKD F+ S + D ES + W+++AFE P SGIN LL A+G F+
Sbjct: 266 DMYCLVGRIYKDMFLESGFIDTESRDKGTFWFKKAFESEPTLQSGINYAVLLLAAGHCFD 325
Query: 1261 NNLEMQQIAVVLNSLLGRKGALQNLMEYWDVATYFEVSVLAENYQKACEAALMMVKLKPP 1440
+ E++++ V ++SLLG+KG+L+ L YW+V ++ S+LA ++ + +A+ + KLK P
Sbjct: 326 TSFELRKVGVKISSLLGKKGSLEKLQSYWEVGSFLAASMLANDHIRVIQASEKLFKLKAP 385
Query: 1441 VWYLKSTMENIKLINRCAATISPIEKEKQQFL--FWSEFFMEATEADTDISCPRYPVLIL 1614
WYLKS ++ I LI + ++P + +Q L FW +F +EAT+ TD+S R+PVLIL
Sbjct: 386 AWYLKSIVDTI-LIYQHFKKLNPEQHTAKQELVDFWMDFLVEATK--TDVSVVRFPVLIL 442
Query: 1615 ELNKEFTPSYLTLNNE--EGTVILSHVLENSQQKKIHQSELRGIHRWHFARNNIKAVTE- 1785
E K + PSYL++N+E E TV + HVL + + +GIH W+F+ +I+ V+
Sbjct: 443 EPTKIYQPSYLSINSEAEEKTVSIWHVLPDDK---------KGIHEWNFSAASIRGVSSN 493
Query: 1786 ------------------------------SKRDDRQLFLYVHENSDDFNLLFPTKAHCK 1875
SK ++R FLYV NSDDF + F T+ HC+
Sbjct: 494 SAVIEVGDKENDSRQMDVNFEGFKNVISLISKFEERCCFLYVLHNSDDFQIYFCTEVHCR 553
Query: 1876 KAYDDMKSMAD-VADGNYQGRVLSNPDNEKIRFEYELSNSNERVVLGKGTYGTVYAARDM 2052
+ +D + S+ + + +G D + + ++YE + ERVVLGKGTYG VYA RD+
Sbjct: 554 RFFDMVNSITEEIGKSTEEGEC----DGDSLEYDYEYDENGERVVLGKGTYGIVYAGRDL 609
Query: 2053 DTQRQIVVKEIEVKYDEEVQPLMEEISLHSTLCHANIVQYLGCDLVGKDGSNDHFLIFME 2232
Q +I +KEI + QPL EEI+LH L H NIVQYLG N IFME
Sbjct: 610 SNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLG-----SLSENGFIKIFME 664
Query: 2233 HVPGGSLSSLLRSKWGPM--NENAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLVNTYS 2406
VPGGSLS+LLRSKWGP+ NE + +Y KQILEGLKYLH+ +IVHRDIKGDNVL+NTYS
Sbjct: 665 QVPGGSLSALLRSKWGPLKNNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYS 724
Query: 2407 GVCKISDFGTCKRLAGLNPVTETFTGTLQYMAPEVIDHGQRGYGAPADIWSFGCTMVEMA 2586
GV KISDFGT KRLAG+NP TETFTGTLQYMAPE+ID G RGYG ADIWS GCT++EMA
Sbjct: 725 GVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMA 784
Query: 2587 TGRPPFVEMQNPQAAMFRVGMFKTHPPIPTEITEKCRNFIKSCFLPEACDRPSAKDLLQD 2766
TG+PPF E+ PQAAMF+VGMFK HP IP ++ + ++FI CF P+ R A +LL D
Sbjct: 785 TGKPPFYELGEPQAAMFKVGMFKIHPEIPESMSAEAKSFILRCFEPDPDKRAFAHELLVD 844
Query: 2767 PFI 2775
F+
Sbjct: 845 EFL 847
Score = 69.7 bits (169), Expect = 6e-10
Identities = 44/169 (26%), Positives = 76/169 (44%), Gaps = 42/169 (24%)
Frame = +1
Query: 3313 FFMLQKDSERRRSLGQFMQDYKDLIIDSWSTLLIKQSDTELV------------------ 3438
FFML+KDSERR +L + + + ++ ++ + L ++ +T+
Sbjct: 943 FFMLKKDSERRATLHRILTEDQEKVVRNLMEALAQEKETDYCRAEGGVRFSIDNSQVNFP 1002
Query: 3439 ------------------------VTVYMLEMLLDGMRDFLLKKDNTKMQKMIDDIRGLL 3546
+ + L+ +R+F+ D + + ++ L
Sbjct: 1003 NQSKSKSEAYAKTQKLSKGAEEPKLKWEHITTLVSSLREFVRSTDRKIIATTLSKLKLEL 1062
Query: 3547 DYDTAKIGQINLALYHFSDSIQPVLRRLDIKPHWMFALSNLITSAVQCA 3693
D+D+ I Q+ L L+ F D++ VLR +IKPHWMFAL N+I AVQ A
Sbjct: 1063 DFDSHGISQVQLVLFGFQDAVNKVLRNHNIKPHWMFALDNIIRKAVQTA 1111