Homology by BLASTX
BLASTX 2.2.4 [Aug-26-2002]
Query= K08B12_5
(4779 letters)
Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
1,967,186 sequences; 661,712,633 total letters
Score E
Sequences producing significant alignments: (bits) Value
gi|25145908|ref|NP_504599.2| protein kinase and Protein kinase C... 3061 0.0
gi|7505496|pir||T25808 hypothetical protein K08B12.5 - Caenorhab... 2930 0.0
gi|39594275|emb|CAE71853.1| Hypothetical protein CBG18897 [Caeno... 2888 0.0
gi|29373942|emb|CAD57746.1| CDC42 binding protein kinase alpha (... 1049 0.0
gi|30089960|ref|NP_055641.3| CDC42-binding protein kinase alpha ... 1049 0.0
gi|31240045|ref|XP_320436.1| ENSANGP00000009214 [Anopheles gambi... 1043 0.0
gi|16758474|ref|NP_446109.1| CDC42-binding protein kinase alpha;... 1041 0.0
gi|27261723|gb|AAN86031.1| CDC42-binding protein kinase beta [Ho... 1040 0.0
gi|30089962|ref|NP_003598.2| CDC42-binding protein kinase alpha ... 1036 0.0
gi|29373940|emb|CAD57745.1| CDC42 binding protein kinase alpha (... 1036 0.0
gi|50756157|ref|XP_415041.1| PREDICTED: similar to CDC42-binding... 1025 0.0
gi|5006445|gb|AAD37506.1| CDC42-binding protein kinase beta [Hom... 1001 0.0
gi|14133241|dbj|BAA86438.2| KIAA1124 protein [Homo sapiens] 999 0.0
gi|16357474|ref|NP_006026.2| CDC42-binding protein kinase beta; ... 999 0.0
gi|33942081|ref|NP_898837.1| Cdc42 binding protein kinase beta [... 998 0.0
gi|16758420|ref|NP_446072.1| Cdc42-binding protein kinase beta [... 997 0.0
gi|30841498|gb|AAP34403.1| CDC42-binding protein kinase beta [Ra... 997 0.0
gi|47222704|emb|CAG00138.1| unnamed protein product [Tetraodon n... 972 0.0
gi|24762562|ref|NP_523837.2| CG4012-PA [Drosophila melanogaster]... 940 0.0
gi|2772930|gb|AAB96643.1| Genghis Khan [Drosophila melanogaster] 937 0.0
gi|50748728|ref|XP_421380.1| PREDICTED: similar to KIAA1124 prot... 914 0.0
gi|50878265|ref|NP_059995.1| myotonic dystrophy protein kinase l... 870 0.0
gi|34861838|ref|XP_219530.2| hypothetical protein XP_219530 [Rat... 857 0.0
gi|47213350|emb|CAF92973.1| unnamed protein product [Tetraodon n... 834 0.0
gi|38084833|ref|XP_140553.3| similar to BC046418 protein [Mus mu... 773 0.0
gi|38073634|ref|XP_283677.2| similar to CDC42-binding protein ki... 747 0.0
gi|48103540|ref|XP_395596.1| similar to ENSANGP00000009214 [Apis... 676 0.0
gi|28839596|gb|AAH47871.1| CDC42BPB protein [Homo sapiens] 655 0.0
gi|27469638|gb|AAH41741.1| Cdc42bpb protein [Xenopus laevis] 609 e-172
gi|1695873|gb|AAB37126.1| ser-thr protein kinase PK428 592 e-167
gi|29387239|gb|AAH48261.1| CDC42BPB protein [Homo sapiens] 578 e-163
gi|41200342|ref|XP_290516.3| myotonic dystrophy protein kinase l... 533 e-149
gi|34855293|ref|XP_218411.2| similar to myotonic dystrophy prote... 468 e-130
gi|1082744|pir||B49364 protein kinase (EC 2.7.1.37), myotonic dy... 467 e-129
gi|633865|gb|AAB31800.1| myotonin protein kinase; MtPK [Homo sap... 467 e-129
gi|181605|gb|AAC14450.1| myotonic dystrophy kinase [Homo sapiens] 467 e-129
gi|181606|gb|AAC14451.1| myotonic dystrophy kinase [Homo sapiens] 466 e-129
gi|181604|gb|AAC14449.1| myotonic dystrophy kinase [Homo sapiens] 466 e-129
gi|47059024|ref|NP_004400.4| myotonic dystrophy protein kinase; ... 466 e-129
gi|14192945|ref|NP_115794.1| dystrophia myotonica kinase, B15 [M... 464 e-128
gi|2137768|pir||S71829 serine/threonine-specific protein kinase ... 464 e-128
gi|300258|gb|AAB26549.1| myotonic dystrophy kinase, DM-kinase {C... 455 e-126
gi|300259|gb|AAB26550.1| myotonic dystrophy kinase, DM-kinase {C... 455 e-126
gi|4885583|ref|NP_005397.1| Rho-associated, coiled-coil containi... 452 e-125
gi|47605964|sp|O77819|ROC1_RABIT Rho-associated protein kinase 1... 446 e-123
gi|6677759|ref|NP_033097.1| Rho-associated coiled-coil forming k... 445 e-123
gi|13592049|ref|NP_112360.1| Rho-associated kinase beta [Rattus ... 442 e-122
gi|34327958|dbj|BAA32296.2| KIAA0451 protein [Homo sapiens] 440 e-121
gi|976147|gb|AAA75239.1| myotonin-protein kinase, Form VI 439 e-121
gi|186756|gb|AAA64884.1| protein kinase 439 e-121
gi|976146|gb|AAA75238.1| myotonin-protein kinase, Form VII 438 e-121
gi|1706450|sp|Q09013|DMK_HUMAN Myotonin-protein kinase (Myotonic... 438 e-121
gi|976145|gb|AAA75237.1| myotonin-protein kinase, Form VIII 438 e-121
gi|50510791|dbj|BAD32381.1| mKIAA1124 protein [Mus musculus] 434 e-119
gi|50737091|ref|XP_419151.1| PREDICTED: similar to corneal epith... 433 e-119
gi|4520225|dbj|BAA75636.1| Rho kinase [Homo sapiens] 429 e-118
gi|40788305|dbj|BAA31594.2| KIAA0619 protein [Homo sapiens] 428 e-118
gi|47605963|sp|O75116|ROC2_HUMAN Rho-associated protein kinase 2... 428 e-118
gi|41872583|ref|NP_004841.2| Rho-associated, coiled-coil contain... 428 e-118
gi|6677761|ref|NP_033098.1| Rho-associated coiled-coil forming k... 427 e-118
gi|48094742|ref|XP_392176.1| similar to Rho-kinase [Apis mellifera] 424 e-117
gi|27806123|ref|NP_776877.1| Rho-associated, coiled-coil contain... 424 e-116
gi|2982220|gb|AAC06351.1| Rho-associated kinase alpha [Xenopus l... 423 e-116
gi|47220321|emb|CAF98420.1| unnamed protein product [Tetraodon n... 422 e-116
gi|15291629|gb|AAK93083.1| LD15203p [Drosophila melanogaster] 417 e-114
gi|24642569|ref|NP_536796.2| CG9774-PA [Drosophila melanogaster]... 417 e-114
gi|6110331|gb|AAF03776.1| Rho-kinase [Drosophila melanogaster] 417 e-114
gi|6981478|ref|NP_037154.1| Rho-associated coiled-coil forming k... 416 e-114
gi|2217968|emb|CAA73006.1| myotonic dystrophy protein kinase lik... 414 e-114
gi|27819643|ref|NP_777288.1| rho-associated, coiled-coil contain... 414 e-113
gi|49898834|gb|AAH75715.1| Dm15 protein [Mus musculus] 413 e-113
gi|13549081|gb|AAK29627.1| Rho-associated coiled-coil forming ki... 405 e-111
gi|34784414|gb|AAH57154.1| Rock1 protein [Mus musculus] 403 e-110
gi|32698688|ref|NP_009105.1| citron; rho-interacting, serine/thr... 396 e-108
gi|976148|gb|AAA75240.1| myotonin-protein kinase, Form II,III,IV 394 e-107
gi|47220115|emb|CAF99028.1| unnamed protein product [Tetraodon n... 387 e-105
gi|33469071|ref|NP_031734.1| citron; citron kinase [Mus musculus... 387 e-105
gi|47224673|emb|CAG03657.1| unnamed protein product [Tetraodon n... 386 e-105
gi|47223803|emb|CAF98573.1| unnamed protein product [Tetraodon n... 386 e-105
gi|50745035|ref|XP_419954.1| PREDICTED: similar to Rho-associate... 377 e-102
gi|39595325|emb|CAE60362.1| Hypothetical protein CBG03960 [Caeno... 369 e-100
gi|17508247|ref|NP_491440.1| rho-associated kinase, LEThal LET-5... 368 e-100
gi|2143504|pir||I78396 myotonic dystrophy kinase - mouse (fragme... 354 1e-95
gi|976143|gb|AAA75235.1| myotonin-protein kinase, Form V 353 3e-95
gi|2143501|pir||I78393 myotonic dystrophy kinase - mouse (fragme... 350 2e-94
gi|2143502|pir||I78394 myotonic dystrophy kinase - mouse (fragme... 350 2e-94
gi|3599507|gb|AAC72822.1| rho/rac-interacting citron kinase shor... 345 6e-93
gi|37784567|gb|AAP43922.1| citron Rho-interacting kinase short f... 343 2e-92
gi|34872621|ref|XP_213796.2| similar to Citron-K kinase [Rattus ... 341 9e-92
gi|3360512|gb|AAC27932.1| Citron-K kinase [Rattus norvegicus] 341 9e-92
gi|31203491|ref|XP_310694.1| ENSANGP00000020013 [Anopheles gambi... 331 1e-88
gi|24663340|ref|NP_648584.1| CG10522-PA [Drosophila melanogaster... 324 1e-86
gi|28386250|gb|AAH46418.1| BC046418 protein [Mus musculus] 318 1e-84
gi|28375481|emb|CAD66559.1| unnamed protein product [Homo sapiens] 308 1e-81
gi|47211559|emb|CAF92353.1| unnamed protein product [Tetraodon n... 300 3e-79
gi|2143503|pir||I78395 myotonic dystrophy kinase - mouse (fragme... 296 2e-78
gi|31213155|ref|XP_315521.1| ENSANGP00000021780 [Anopheles gambi... 290 3e-76
gi|24667016|ref|NP_524170.2| CG8637-PA [Drosophila melanogaster]... 289 5e-76
gi|9716484|gb|AAF97511.1| NDR kinase [Drosophila melanogaster] 286 3e-75
gi|853820|emb|CAA84486.1| Ndr protein kinase [Drosophila melanog... 278 7e-73
gi|38085310|ref|XP_283676.2| similar to CDC42-binding protein ki... 277 2e-72
gi|7677439|gb|AAF67167.1| NDR protein kinase [Drosophila melanog... 276 5e-72
gi|19075145|ref|NP_586746.1| PROTEIN KINASE C (EPSILON TYPE) [En... 274 1e-71
gi|13549083|gb|AAK29628.1| Rho-associated coiled coil forming ki... 247 2e-63
gi|50756691|ref|XP_415277.1| PREDICTED: similar to citron; rho-i... 242 6e-62
gi|47156963|gb|AAT12343.1| protein kinase C [Antonospora locustae] 240 3e-61
gi|29612442|gb|AAH49921.1| Cdc42bpb protein [Mus musculus] 236 4e-60
gi|32414173|ref|XP_327566.1| hypothetical protein ( (AY029769) p... 227 2e-57
gi|19115752|ref|NP_594840.1| serine/threonine protein kinase [Sc... 225 7e-57
gi|46122935|ref|XP_386021.1| hypothetical protein FG05845.1 [Gib... 224 1e-56
gi|45185202|ref|NP_982919.1| ABL028Wp [Eremothecium gossypii] >g... 224 2e-56
gi|38110989|gb|EAA56628.1| hypothetical protein MG06599.4 [Magna... 222 6e-56
gi|458284|gb|AAA57318.1| serine/threonine protein kinase 221 1e-55
gi|19075510|ref|NP_588010.1| putative proliferation-associated s... 221 1e-55
gi|445069|prf||1908384A protein kinase 221 2e-55
gi|6322723|ref|NP_012796.1| 76.5 kDa Serine/threonine protein ki... 221 2e-55
gi|172181|gb|AAA34880.1| protein kinase 221 2e-55
gi|49067618|ref|XP_398099.1| hypothetical protein UM00484.1 [Ust... 221 2e-55
gi|31201487|ref|XP_309691.1| ENSANGP00000012571 [Anopheles gambi... 220 2e-55
gi|50304295|ref|XP_452097.1| unnamed protein product [Kluyveromy... 220 3e-55
gi|1730069|sp|P54644|KRAC_DICDI RAC-family serine/threonine-prot... 219 4e-55
gi|15072452|gb|AAK40343.1| protein kinase 1 [Cryphonectria paras... 219 7e-55
gi|49097300|ref|XP_410110.1| hypothetical protein AN5973.2 [Aspe... 218 9e-55
gi|50552438|ref|XP_503629.1| hypothetical protein [Yarrowia lipo... 218 1e-54
gi|24664679|ref|NP_648778.1| CG6498-PA [Drosophila melanogaster]... 218 1e-54
gi|464395|sp|P28178|PK2_DICDI Protein kinase 2 >gnl|BL_ORD_ID|12... 217 3e-54
gi|50291879|ref|XP_448372.1| unnamed protein product [Candida gl... 217 3e-54
gi|15219539|ref|NP_175130.1| protein kinase family protein [Arab... 216 4e-54
gi|6323751|ref|NP_013822.1| protein kinase; Ypk2p [Saccharomyces... 215 7e-54
gi|38073632|ref|XP_355257.1| similar to CDC42-binding protein ki... 214 2e-53
gi|47225434|emb|CAG11917.1| unnamed protein product [Tetraodon n... 214 2e-53
gi|39592150|emb|CAE75370.1| Hypothetical protein CBG23354 [Caeno... 214 2e-53
gi|445070|prf||1908384B protein kinase 214 2e-53
gi|19923570|ref|NP_066958.2| ribosomal protein S6 kinase, 90kDa,... 213 3e-53
gi|32450549|gb|AAH54113.1| Rps6ka6 protein [Mus musculus] 213 3e-53
gi|33303975|gb|AAQ02495.1| ribosomal protein S6 kinase, 90kDa, p... 213 3e-53
gi|29789163|ref|NP_080225.1| ribosomal protein S6 kinase polypep... 213 3e-53
gi|50745818|ref|XP_420257.1| PREDICTED: similar to Ribosomal pro... 213 4e-53
gi|48101869|ref|XP_392717.1| similar to microtubule associated s... 213 4e-53
gi|7504545|pir||T22856 hypothetical protein F57F5.5 - Caenorhabd... 213 5e-53
gi|17562588|ref|NP_506014.1| protein kinase C (80.2 kD) (pkc-1) ... 213 5e-53
gi|6166243|sp|Q15349|K6A2_HUMAN Ribosomal protein S6 kinase alph... 212 6e-53
gi|46433231|gb|EAK92679.1| hypothetical protein CaO19.399 [Candi... 212 6e-53
gi|125547|sp|P13678|KPC3_DROME Protein kinase C (PKC) (dPKC98F) ... 212 8e-53
gi|401772|gb|AAC82496.1| ribosomal protein S6 kinase 2 [Homo sap... 212 8e-53
gi|24650924|ref|NP_524545.2| CG1954-PA [Drosophila melanogaster]... 212 8e-53
gi|12860267|dbj|BAB31901.1| unnamed protein product [Mus musculus] 211 1e-52
gi|50427081|ref|XP_462147.1| unnamed protein product [Debaryomyc... 211 1e-52
gi|2065190|emb|CAA72926.1| protein kinase C [Hydra vulgaris] 211 1e-52
gi|17136402|ref|NP_476682.1| CG6622-PA [Drosophila melanogaster]... 211 1e-52
gi|24654282|ref|NP_725626.1| CG6622-PB [Drosophila melanogaster]... 211 1e-52
gi|630707|pir||A53530 protein kinase C (EC 2.7.1.-) epsilon-rela... 211 2e-52
gi|23478593|gb|EAA15636.1| kinase Akt/PKB-related [Plasmodium yo... 211 2e-52
gi|13676454|dbj|BAB41150.1| hypothetical protein [Macaca fascicu... 211 2e-52
gi|39584758|emb|CAE67653.1| Hypothetical protein CBG13216 [Caeno... 210 2e-52
gi|6755374|ref|NP_035429.1| ribosomal protein S6 kinase, polypep... 210 3e-52
gi|50761545|ref|XP_424758.1| PREDICTED: similar to KIAA0303 [Gal... 210 3e-52
gi|50292225|ref|XP_448545.1| unnamed protein product [Candida gl... 210 3e-52
gi|7657526|ref|NP_055311.1| ribosomal protein S6 kinase, 90kDa, ... 210 3e-52
gi|14326578|gb|AAK60333.1| At1g48490/T1N15_9 [Arabidopsis thalia... 210 3e-52
gi|50741701|ref|XP_419611.1| PREDICTED: similar to ribosomal pro... 210 3e-52
gi|33303997|gb|AAQ02506.1| ribosomal protein S6 kinase, 90kDa, p... 210 3e-52
gi|28300431|gb|AAO37581.1| RPS6KA2 [Mus musculus] 210 3e-52
gi|18402213|ref|NP_564529.1| protein kinase, putative [Arabidops... 210 3e-52
gi|11181910|emb|CAC16111.1| bA54F22.1.1 (ribosomal protein S6 ki... 210 3e-52
gi|25005142|gb|AAN71007.1| ribosomal protein S6 kinase [Mus musc... 210 3e-52
gi|50740446|ref|XP_419464.1| PREDICTED: similar to Protein kinas... 209 4e-52
gi|34853530|ref|XP_226732.2| similar to KIAA0303 [Rattus norvegi... 209 4e-52
gi|50755717|ref|XP_414868.1| PREDICTED: similar to Protein kinas... 209 5e-52
gi|22085162|gb|AAM90321.1| putative protein kinase C epsilon [Li... 209 5e-52
gi|47213332|emb|CAF93963.1| unnamed protein product [Tetraodon n... 209 5e-52
gi|507141|gb|AAA19440.1| cAMP-dependent protein kinase catalytic... 209 7e-52
gi|49168616|emb|CAG38803.1| RPS6KA6 [Homo sapiens] 209 7e-52
gi|631936|pir||S41099 protein kinase (EC 2.7.1.37), cAMP-depende... 209 7e-52
gi|545623|gb|AAB30032.1| cAMP-dependent protein kinase C subunit... 209 7e-52
gi|33243964|gb|AAH55331.1| Ribosomal protein S6 kinase, polypept... 208 9e-52
gi|37550319|ref|XP_291141.3| KIAA0303 protein [Homo sapiens] 208 9e-52
gi|41056055|ref|NP_956367.1| Unknown (protein for MGC:66139); wu... 208 9e-52
gi|6537166|gb|AAF15553.1| Rsk-2 [Xenopus laevis] 208 9e-52
gi|2224547|dbj|BAA20762.1| KIAA0303 [Homo sapiens] 208 9e-52
gi|16648134|gb|AAL25332.1| GH13631p [Drosophila melanogaster] 208 1e-51
gi|28302248|gb|AAH46697.1| Kin-1-prov protein [Xenopus laevis] 208 1e-51
gi|6016444|sp|Q16975|KPC2_APLCA Calcium-independent protein kina... 208 1e-51
gi|27769312|gb|AAH42511.1| 4930420O11Rik protein [Mus musculus] 208 1e-51
gi|38075057|ref|XP_283179.2| RIKEN cDNA 4930420O11 [Mus musculus] 207 2e-51
gi|6981398|ref|NP_036845.1| protein kinase C, beta; protein kina... 207 3e-51
gi|47157322|ref|NP_997700.1| protein kinase C, beta isoform 1; p... 207 3e-51
gi|125540|sp|P04410|KPCB_MOUSE Protein kinase C, beta type (PKC-... 207 3e-51
gi|2822146|gb|AAB97933.1| Protein kinase C beta (5' partial) spl... 207 3e-51
gi|4885563|ref|NP_005391.1| protein kinase C, epsilon [Homo sapi... 207 3e-51
gi|66734|pir||KIRBCE protein kinase C (EC 2.7.1.-) epsilon - rabbit 207 3e-51
gi|125556|sp|P10830|KPCE_RABIT Protein kinase C, epsilon type (n... 207 3e-51
gi|31206439|ref|XP_312175.1| ENSANGP00000022036 [Anopheles gambi... 206 3e-51
gi|125539|sp|P05772|KPCB_RABIT Protein kinase C, beta type (PKC-... 206 3e-51
gi|26006211|dbj|BAC41448.1| mKIAA0807 protein [Mus musculus] 206 3e-51
gi|125563|sp|P23298|KPCL_MOUSE Protein kinase C, eta type (nPKC-... 206 3e-51
gi|15241795|ref|NP_201037.1| incomplete root hair elongation (IR... 206 3e-51
gi|49359177|gb|AAT65503.1| protein kinase C epsilon [Rattus norv... 206 3e-51
gi|47226221|emb|CAG08368.1| unnamed protein product [Tetraodon n... 206 3e-51
gi|50730201|ref|XP_416804.1| PREDICTED: similar to ribosomal pro... 206 4e-51
gi|38090984|ref|XP_358017.1| similar to Rho-associated kinase be... 206 4e-51
gi|49073748|ref|XP_401061.1| hypothetical protein UM03446.1 [Ust... 206 4e-51
gi|66721|pir||KIRTC1 protein kinase C (EC 2.7.1.-) beta-I - rat ... 206 6e-51
gi|15808364|emb|CAC88367.1| cAMP-dependent protein kinase cataly... 206 6e-51
gi|47230027|emb|CAG10441.1| unnamed protein product [Tetraodon n... 206 6e-51
gi|38511949|gb|AAH60703.1| Mast2 protein [Mus musculus] 206 6e-51
gi|17555946|ref|NP_499447.1| s6 kinase (3M341) [Caenorhabditis e... 206 6e-51
gi|6755084|ref|NP_035234.1| protein kinase C, epsilon [Mus muscu... 206 6e-51
gi|34870261|ref|XP_233782.2| similar to protein kinase [Rattus n... 206 6e-51
gi|6678958|ref|NP_032667.1| microtubule associated serine/threon... 206 6e-51
gi|31543511|ref|NP_032882.2| protein kinase C, eta [Mus musculus... 205 8e-51
gi|48104993|ref|XP_395876.1| similar to p70 ribosomal protein S6... 205 1e-50
gi|50254457|gb|EAL17206.1| hypothetical protein CNBN0340 [Crypto... 205 1e-50
gi|13592027|ref|NP_112347.1| protein kinase C-eta [Rattus norveg... 205 1e-50
gi|2117824|pir||I51901 ribosomal protein S6 kinase 2 (EC 2.7.1.-... 204 1e-50
gi|20149547|ref|NP_002944.2| ribosomal protein S6 kinase, 90kDa,... 204 1e-50
gi|29294760|gb|AAH49076.1| Rps6ka1 protein [Mus musculus] 204 1e-50
gi|33988322|gb|AAH15816.2| MAST2 protein [Homo sapiens] 204 1e-50
gi|40788866|dbj|BAA34527.2| KIAA0807 protein [Homo sapiens] 204 1e-50
gi|14149671|ref|NP_055927.1| microtubule associated serine/threo... 204 1e-50
gi|41350925|gb|AAH65499.1| MAST205 protein [Homo sapiens] 204 1e-50
gi|39930373|ref|NP_058867.1| protein kinase C, epsilon [Rattus n... 204 1e-50
gi|125692|sp|P18652|K6AA_CHICK Ribosomal protein S6 kinase II al... 204 2e-50
gi|47213969|emb|CAG00660.1| unnamed protein product [Tetraodon n... 204 2e-50
gi|27807059|ref|NP_777010.1| cAMP-dependent protein kinase catal... 204 2e-50
gi|4506057|ref|NP_002722.1| cAMP-dependent protein kinase cataly... 204 2e-50
gi|9910296|ref|NP_064329.1| microtubule associated serine/threon... 204 2e-50
gi|39593304|emb|CAE64774.1| Hypothetical protein CBG09565 [Caeno... 204 2e-50
gi|13592065|ref|NP_112369.1| S6 protein kinase (Rsk-1) [Rattus n... 204 2e-50
gi|50417908|gb|AAH78343.1| Unknown (protein for MGC:91856) [Dani... 203 3e-50
gi|45120119|ref|NP_055790.1| microtubule associated serine/threo... 203 3e-50
gi|4759050|ref|NP_004577.1| ribosomal protein S6 kinase, 90kDa, ... 203 3e-50
gi|22507357|ref|NP_683747.1| ribosomal protein S6 kinase polypep... 203 3e-50
gi|11360323|pir||T45070 protein kinase homolog R31240_1 [importe... 203 3e-50
gi|33354095|dbj|BAC81131.1| RPS6KA3 [Homo sapiens] >gnl|BL_ORD_I... 203 3e-50
gi|24658719|ref|NP_523941.2| CG10539-PA [Drosophila melanogaster... 203 3e-50
gi|28557781|ref|NP_006246.2| protein kinase C, eta [Homo sapiens... 203 3e-50
gi|401774|gb|AAC82495.1| ribosomal protein S6 kinase 3 [Homo sap... 203 3e-50
gi|33304069|gb|AAQ02542.1| ribosomal protein S6 kinase, 90kDa, p... 203 3e-50
gi|4589590|dbj|BAA76817.1| KIAA0973 protein [Homo sapiens] 203 3e-50
gi|38109783|gb|EAA55600.1| hypothetical protein MG01251.4 [Magna... 203 4e-50
gi|32452024|gb|AAH54524.1| Sast-pending protein [Mus musculus] 203 4e-50
gi|30842796|ref|NP_851603.1| syntrophin associated serine/threon... 203 4e-50
gi|50751534|ref|XP_422443.1| PREDICTED: similar to Mast2 protein... 203 4e-50
gi|29373055|gb|AAO72535.1| syntrophin-associated serine/threonin... 203 4e-50
gi|50255581|gb|EAL18314.1| hypothetical protein CNBJ2370 [Crypto... 203 4e-50
gi|50748818|ref|XP_421417.1| PREDICTED: similar to protein kinas... 203 4e-50
gi|39104501|dbj|BAC65693.3| mKIAA0973 protein [Mus musculus] 203 4e-50
gi|50415396|gb|AAH78067.1| Unknown (protein for MGC:82916) [Xeno... 203 4e-50
gi|47230126|emb|CAG10540.1| unnamed protein product [Tetraodon n... 203 4e-50
gi|50731568|ref|XP_418280.1| PREDICTED: similar to Serine/threon... 203 4e-50
gi|4506055|ref|NP_002721.1| cAMP-dependent protein kinase cataly... 202 5e-50
gi|34978340|sp|P36887|KAPA_PIG cAMP-dependent protein kinase, al... 202 5e-50
gi|39595602|emb|CAE67103.1| Hypothetical protein CBG12516 [Caeno... 202 5e-50
gi|12060812|gb|AAG48248.1| p70 ribosomal protein S6 kinase [Arte... 202 5e-50
gi|19113760|ref|NP_592848.1| putative serine/threonine protein k... 202 5e-50
gi|34853790|ref|XP_341759.1| ribosomal protein S6 kinase, 90kD, ... 202 5e-50
gi|2911462|gb|AAC04357.1| serine/threonine protein kinase [Colle... 202 5e-50
gi|50546807|ref|XP_500873.1| hypothetical protein [Yarrowia lipo... 202 5e-50
gi|47224750|emb|CAG00344.1| unnamed protein product [Tetraodon n... 202 5e-50
gi|493956|pdb|1CTP|E Chain E, Camp-Dependent Protein Kinase (E.C... 202 5e-50
gi|50417448|gb|AAH77281.1| Unknown (protein for MGC:80071) [Xeno... 202 6e-50
gi|23272313|gb|AAH35058.1| CAMP-dependent protein kinase catalyt... 202 6e-50
gi|37552548|ref|XP_038150.3| microtubule associated serine/threo... 202 6e-50
gi|1346393|sp|P24723|KPCL_HUMAN Protein kinase C, eta type (nPKC... 202 6e-50
gi|83398|pir||S22258 probable protein kinase KIN82 (EC 2.7.1.-) ... 202 6e-50
gi|49256532|gb|AAH71102.1| Unknown (protein for MGC:81220) [Xeno... 202 6e-50
gi|476509|pir||OKHUCG protein kinase (EC 2.7.1.37), cAMP-depende... 202 6e-50
gi|3043646|dbj|BAA25487.1| KIAA0561 protein [Homo sapiens] 202 6e-50
gi|125694|sp|P10666|K6AB_XENLA Ribosomal protein S6 kinase II be... 202 6e-50
gi|34877594|ref|XP_237971.2| similar to KIAA0561 protein [Rattus... 202 8e-50
gi|1778160|gb|AAC47429.1| 70 kDa S6 kinase [Drosophila melanogas... 202 8e-50
gi|50751398|ref|XP_422379.1| PREDICTED: similar to cAMP-dependen... 202 8e-50
gi|48097317|ref|XP_391874.1| similar to ENSANGP00000009078 [Apis... 202 8e-50
gi|6755076|ref|NP_035230.1| protein kinase, cAMP dependent, cata... 201 1e-49
gi|7110693|ref|NP_032880.1| protein kinase, cAMP dependent, cata... 201 1e-49
gi|34098738|sp|Q9MZD9|KAPA_SHEEP cAMP-dependent protein kinase, ... 201 1e-49
gi|27807057|ref|NP_777009.1| cAMP-dependent protein kinase catal... 201 1e-49
gi|125204|sp|P25321|KAPA_CRIGR cAMP-dependent protein kinase, al... 201 1e-49
gi|33860165|sp|P05383|KAPB_PIG cAMP-dependent protein kinase, be... 201 1e-49
gi|17390848|gb|AAH18363.1| Sgk3 protein [Mus musculus] 201 1e-49
gi|125551|sp|P10102|KPCA_RABIT Protein kinase C, alpha type (PKC... 201 1e-49
gi|349816|pdb|1APM|E Chain E, c-AMP-Dependent Protein Kinase (E.... 201 1e-49
gi|230462|pdb|2CPK|E Chain E, c-AMP-Dependent Protein Kinase (E.... 201 1e-49
gi|26327211|dbj|BAC27349.1| unnamed protein product [Mus musculus] 201 1e-49
gi|18959280|ref|NP_573483.1| serum/glucocorticoid regulated kina... 201 1e-49
gi|15808362|emb|CAC88366.1| cAMP-dependent protein kinase cataly... 201 1e-49
gi|10383810|ref|NP_010015.2| Putative serine/threonine protein k... 201 1e-49
gi|34098572|sp|Q8MJ44|KAPA_CANFA cAMP-dependent protein kinase, ... 201 1e-49
gi|125218|sp|P24256|KAPI_BOVIN cAMP-dependent protein kinase, be... 201 1e-49
gi|33636738|ref|NP_891993.1| cAMP-dependent protein kinase catal... 201 1e-49
gi|25058324|gb|AAH39888.1| Protein kinase, cAMP-dependent, catal... 201 2e-49
gi|6466010|gb|AAF12758.1| protein kinase [Homo sapiens] >gnl|BL_... 201 2e-49
gi|47085805|ref|NP_998241.1| zgc:55713 [Danio rerio] >gnl|BL_ORD... 201 2e-49
gi|47216574|emb|CAG00609.1| unnamed protein product [Tetraodon n... 201 2e-49
gi|125552|sp|P05696|KPCA_RAT Protein kinase C, alpha type (PKC-a... 201 2e-49
gi|66717|pir||KIMSCA protein kinase C (EC 2.7.1.-) alpha - mouse... 201 2e-49
gi|4506067|ref|NP_002728.1| protein kinase C, alpha; protein kin... 201 2e-49
gi|34874121|ref|XP_343976.1| protein kinase C, alpha [Rattus nor... 201 2e-49
gi|33303813|gb|AAQ02420.1| serum/glucocorticoid regulated kinase... 201 2e-49
gi|47216412|emb|CAG01963.1| unnamed protein product [Tetraodon n... 201 2e-49
gi|2914581|pdb|1FMO|E Chain E, Crystal Structure Of A Polyhistid... 201 2e-49
gi|2981777|pdb|1BKX|A Chain A, A Binary Complex Of The Catalytic... 201 2e-49
gi|50513587|pdb|1SMH|A Chain A, Protein Kinase A Variant Complex... 201 2e-49
gi|576052|pdb|1CMK|E Chain E, Camp-Dependent Protein Kinase Cata... 201 2e-49
gi|2982123|pdb|1STC|E Chain E, Camp-Dependent Protein Kinase, Al... 201 2e-49
gi|28948416|pdb|1J3H|A Chain A, Crystal Structure Of Apoenzyme C... 201 2e-49
gi|6225593|sp|Q16974|KPC1_APLCA Calcium-dependent protein kinase... 201 2e-49
gi|228058|prf||1716374A protein kinase C I 201 2e-49
gi|31563382|ref|NP_037389.4| serum/glucocorticoid regulated kina... 201 2e-49
gi|20127541|ref|NP_057360.2| serum/glucocorticoid regulated kina... 200 2e-49
gi|125207|sp|P27791|KAPA_RAT cAMP-dependent protein kinase, alph... 200 2e-49
gi|39794417|gb|AAH64239.1| LOC394938 protein [Xenopus tropicalis] 200 2e-49
gi|3114989|emb|CAA73554.1| Serine/Threonine protein kinase [Syco... 200 2e-49
gi|33303995|gb|AAQ02505.1| serum/glucocorticoid regulated kinase... 200 2e-49
gi|20151205|pdb|1L3R|E Chain E, Crystal Structure Of A Transitio... 200 2e-49
gi|40889426|pdb|1Q8W|A Chain A, The Catalytic Subunit Of Camp-De... 200 2e-49
gi|14719578|pdb|1JBP|E Chain E, Crystal Structure Of The Catalyt... 200 2e-49
gi|17402861|gb|AAF27051.2| SGK-like protein SGKL [Homo sapiens] 200 2e-49
gi|33878427|gb|AAH14037.2| SGK2 protein [Homo sapiens] 200 2e-49
gi|25168261|ref|NP_733794.1| serum/glucocorticoid regulated kina... 200 2e-49
gi|33300395|emb|CAE17938.1| Hypothetical protein T01H8.1c [Caeno... 200 3e-49
gi|17508705|ref|NP_492320.1| ribosomal protein S6 kinase (rsk-1)... 200 3e-49
gi|37927861|pdb|1Q61|A Chain A, Pka Triple Mutant Model Of Pkb 200 3e-49
gi|33300393|emb|CAB02301.2| Hypothetical protein T01H8.1b [Caeno... 200 3e-49
gi|17508707|ref|NP_492319.1| ribosomal protein S6 kinase (rsk-1)... 200 3e-49
gi|45645188|sp|Q21734|KS6A_CAEEL Putative ribosomal protein S6 k... 200 3e-49
gi|89281|pir||S00085 protein kinase (EC 2.7.1.37), cAMP-dependen... 200 3e-49
gi|200367|gb|AAA39936.1| cAMP-dependent protein kinase catalytic... 199 4e-49
gi|15619015|ref|NP_002723.2| protein kinase, cAMP-dependent, cat... 199 4e-49
gi|50758354|ref|XP_415882.1| PREDICTED: similar to Ribosomal pro... 199 4e-49
gi|27806089|ref|NP_776860.1| protein kinase, C alpha [Bos taurus... 199 4e-49
gi|19075783|ref|NP_588283.1| probable serine-threonine-protein k... 199 4e-49
gi|9844082|emb|CAC03748.1| cAMP-dependent protein kinase catalyt... 199 4e-49
gi|49259182|pdb|1SZM|A Chain A, Dual Binding Mode Of Bisindolylm... 199 4e-49
gi|2098410|pdb|1YDT|E Chain E, Structure Of Camp-Dependent Prote... 199 4e-49
gi|34810567|pdb|1Q24|A Chain A, Pka Double Mutant Model Of Pkb I... 199 4e-49
gi|50547917|ref|XP_501428.1| hypothetical protein [Yarrowia lipo... 199 4e-49
gi|22023043|emb|CAD30698.1| protein kinase C, alpha type [Takifu... 199 4e-49
gi|20385903|gb|AAM21494.1| protein kinase Sch9 [Cryptococcus neo... 199 4e-49
gi|31418467|gb|AAH53365.1| Unknown (protein for MGC:61512) [Homo... 199 5e-49
gi|26328523|dbj|BAC28000.1| unnamed protein product [Mus musculus] 199 5e-49
gi|109371|pir||S12906 probable ribosomal protein S6 kinase (EC 2... 199 5e-49
gi|125695|sp|P23443|K6B1_HUMAN Ribosomal protein S6 kinase (S6K)... 199 5e-49
gi|23512346|gb|AAH38491.1| Rps6kb1 protein [Mus musculus] 199 5e-49
gi|4506737|ref|NP_003152.1| ribosomal protein S6 kinase, 70kDa, ... 199 5e-49
gi|125696|sp|P21425|K6B1_RAT Ribosomal protein S6 kinase I (S6K)... 199 5e-49
gi|46909584|ref|NP_997401.1| cAMP-dependent protein kinase catal... 199 5e-49
gi|125208|sp|P06244|KAPA_YEAST cAMP-dependent protein kinase typ... 199 5e-49
gi|33304209|gb|AAQ02612.1| ribosomal protein S6 kinase, 70kDa, p... 199 5e-49
gi|45430051|ref|NP_991385.1| p70S6K [Bos taurus] >gnl|BL_ORD_ID|... 199 5e-49
gi|50550707|ref|XP_502826.1| hypothetical protein [Yarrowia lipo... 199 5e-49
gi|3688803|gb|AAC62398.1| unknown [Xenopus laevis] 199 5e-49
gi|49116933|gb|AAH73077.1| Sgk protein [Xenopus laevis] 199 5e-49
gi|17570293|ref|NP_510647.1| serum and Glucocorticoid inducible ... 199 7e-49
gi|50757861|ref|XP_415682.1| PREDICTED: similar to Protein kinas... 199 7e-49
gi|104167|pir||A37237 protein kinase C (EC 2.7.1.-) I - African ... 199 7e-49
gi|49118486|gb|AAH73469.1| Rps6kb1-A protein [Xenopus laevis] 199 7e-49
gi|13605770|gb|AAK32877.1| 90-kDa ribosomal protein S6 kinase [R... 199 7e-49
gi|19310195|dbj|BAB85907.1| p90 ribosomal S6 kinase [Asterina pe... 199 7e-49
gi|4582255|emb|CAB40193.1| kinase [Xenopus laevis] 199 7e-49
gi|47220928|emb|CAG03461.1| unnamed protein product [Tetraodon n... 199 7e-49
gi|3411161|gb|AAC67395.1| mitogen- and stress-activated protein ... 198 9e-49
gi|55132|emb|CAA36907.1| protein kinase C [Mus musculus] >gnl|BL... 198 9e-49
gi|2144416|pir||OKBYC1 protein kinase (EC 2.7.1.37), cAMP-depend... 198 9e-49
gi|28971730|dbj|BAC65325.1| testis catalytic subunit of cyclic a... 198 9e-49
gi|17980212|gb|AAL50556.1| serine-threonine protein kinase PK2 [... 198 9e-49
gi|4506735|ref|NP_003933.1| ribosomal protein S6 kinase, 90kDa, ... 198 9e-49
gi|50425563|ref|XP_461377.1| unnamed protein product [Debaryomyc... 198 1e-48
gi|3116066|emb|CAA11528.1| s-sgk2 [Squalus acanthias] 198 1e-48
gi|4625|emb|CAA68689.1| unnamed protein product [Saccharomyces c... 198 1e-48
gi|8568077|gb|AAF76424.1| sperm cAMP-dependent protein kinase ca... 198 1e-48
gi|40363533|ref|NP_954682.1| serum/glucocorticoid regulated kina... 198 1e-48
gi|125693|sp|P10665|K6AA_XENLA Ribosomal protein S6 kinase II al... 198 1e-48
gi|3114956|emb|CAA73553.1| Serine/Threonine protein kinase [Sube... 198 1e-48
gi|50604098|gb|AAH78065.1| Unknown (protein for MGC:82897) [Xeno... 197 2e-48
gi|3116064|emb|CAA11527.1| s-sgk1 [Squalus acanthias] 197 2e-48
gi|14719777|pdb|1FOT|A Chain A, Structure Of The Unliganded Camp... 197 2e-48
gi|125550|sp|P20444|KPCA_MOUSE Protein kinase C, alpha type (PKC... 197 2e-48
gi|6755078|ref|NP_035231.1| protein kinase C, alpha [Mus musculu... 197 2e-48
gi|49079306|ref|XP_403313.1| hypothetical protein UM05698.1 [Ust... 197 2e-48
gi|50420447|ref|XP_458760.1| unnamed protein product [Debaryomyc... 197 2e-48
gi|28839796|gb|AAH47896.1| RPS6KA4 protein [Homo sapiens] 197 2e-48
gi|48425310|pdb|1RDQ|E Chain E, Hydrolysis Of Atp In The Crystal... 197 2e-48
gi|25168263|ref|NP_005618.2| serum/glucocorticoid regulated kina... 197 3e-48
gi|34860642|ref|XP_342571.1| serum/glucocorticoid regulated kina... 197 3e-48
gi|227604|prf||1707301A protein kinase 197 3e-48
gi|50303809|ref|XP_451851.1| unnamed protein product [Kluyveromy... 197 3e-48
gi|6321999|ref|NP_012075.1| protein kinase involved in growth co... 197 3e-48
gi|4426|emb|CAA31073.1| unnamed protein product [Saccharomyces c... 197 3e-48
gi|173011|gb|AAA35165.1| cAMP-dependent protein kinase subunit (... 197 3e-48
gi|6324375|ref|NP_014445.1| Putative protein kinase that, when o... 197 3e-48
gi|33303865|gb|AAQ02446.1| serum/glucocorticoid regulated kinase... 197 3e-48
gi|50287865|ref|XP_446362.1| unnamed protein product [Candida gl... 197 3e-48
gi|730723|sp|P11792|SCH9_YEAST Serine/threonine-protein kinase S... 197 3e-48
gi|39596349|emb|CAE69987.1| Hypothetical protein CBG16386 [Caeno... 197 3e-48
gi|15277982|gb|AAH12964.1| Ribosomal protein S6 kinase, polypept... 197 3e-48
gi|47215419|emb|CAG01116.1| unnamed protein product [Tetraodon n... 196 4e-48
gi|6325053|ref|NP_015121.1| Involved in nutrient control of cell... 196 4e-48
gi|47086473|ref|NP_997951.1| ribosomal protein S6 kinase polypep... 196 4e-48
gi|11596395|gb|AAG38600.1| cAMP-dependent protein kinase catalyt... 196 4e-48
gi|31205767|ref|XP_311835.1| ENSANGP00000018211 [Anopheles gambi... 196 4e-48
gi|46436399|gb|EAK95762.1| hypothetical protein CaO19.9817 [Cand... 196 4e-48
gi|49093828|ref|XP_408375.1| hypothetical protein AN4238.2 [Aspe... 196 4e-48
gi|49257650|gb|AAH74305.1| Unknown (protein for MGC:84110) [Xeno... 196 4e-48
gi|12620233|gb|AAG60621.1| S6 kinase [Aplysia californica] 196 5e-48
gi|46442847|gb|EAL02133.1| hypothetical protein CaO19.829 [Candi... 196 5e-48
gi|45383215|ref|NP_989807.1| serum- and glucocorticoid-induced k... 196 5e-48
gi|7305483|ref|NP_038759.1| serum/glucocorticoid regulated kinas... 196 5e-48
gi|14010889|ref|NP_114191.1| S6 kinase [Rattus norvegicus] >gnl|... 196 6e-48
gi|3914977|sp|O00141|SGK1_HUMAN Serine/threonine-protein kinase ... 195 8e-48
gi|477098|pir||A48094 serum and glucocorticoid-regulated kinase ... 195 8e-48
gi|4322298|gb|AAD16003.1| cAMP-dependent protein kinase catalyti... 195 8e-48
gi|46909485|gb|AAT06260.1| protein kinase B-like protein [Plasmo... 195 8e-48
gi|31216024|ref|XP_316151.1| ENSANGP00000020399 [Anopheles gambi... 195 8e-48
gi|23509142|ref|NP_701810.1| rac-beta serine/threonine protein k... 195 8e-48
gi|50303505|ref|XP_451694.1| unnamed protein product [Kluyveromy... 195 8e-48
gi|2565330|gb|AAC24243.1| cAMP-dependent protein kinase catalyti... 195 8e-48
gi|49068900|ref|XP_398739.1| hypothetical protein UM01124.1 [Ust... 195 8e-48
gi|13431833|sp|Q9XT18|SGK1_RABIT Serine/threonine-protein kinase... 195 1e-47
gi|6755490|ref|NP_035491.1| serum/glucocorticoid regulated kinas... 195 1e-47
gi|9507093|ref|NP_062105.1| serum/glucocorticoid regulated kinas... 195 1e-47
gi|47124333|gb|AAH70401.1| Sgk protein [Mus musculus] 195 1e-47
gi|21537155|gb|AAM61496.1| putative ribosomal-protein S6 kinase ... 195 1e-47
gi|6322297|ref|NP_012371.1| putative catalytic subunit of cAMP-d... 195 1e-47
gi|47086403|ref|NP_997980.1| v-akt murine thymoma viral oncogene... 195 1e-47
gi|45198429|ref|NP_985458.1| AFL090Wp [Eremothecium gossypii] >g... 195 1e-47
gi|39587559|emb|CAE58497.1| Hypothetical protein CBG01645 [Caeno... 194 1e-47
gi|32425471|gb|AAH06106.2| RPS6KB2 protein [Homo sapiens] 194 1e-47
gi|45190492|ref|NP_984746.1| AEL115Cp [Eremothecium gossypii] >g... 194 1e-47
gi|50288647|ref|XP_446753.1| unnamed protein product [Candida gl... 194 1e-47
gi|25141296|ref|NP_740958.1| cyclic AMP-dependent catalytic subu... 194 1e-47
gi|15231960|ref|NP_187485.1| serine/threonine protein kinase (PK... 194 1e-47
gi|462434|sp|P34099|KAPC_DICDI cAMP-dependent protein kinase cat... 194 1e-47
gi|9910454|ref|NP_064308.1| ribosomal protein S6 kinase, polypep... 194 1e-47
gi|48126576|ref|XP_393285.1| similar to putative cAMP-dependent ... 194 1e-47
gi|7578502|gb|AAF64072.1| protein kinase A [Candida albicans] 194 2e-47
gi|9858999|gb|AAD00706.3| putative protein kinase A catalytic su... 194 2e-47
gi|11230513|emb|CAC03986.2| putative protein kinase A catalytic ... 194 2e-47
gi|45187484|ref|NP_983707.1| ADL389Wp [Eremothecium gossypii] >g... 194 2e-47
gi|46107178|ref|XP_380648.1| hypothetical protein FG00472.1 [Gib... 194 2e-47
gi|28279352|gb|AAH46261.1| Akt2-prov protein [Xenopus laevis] 194 2e-47
gi|4502023|ref|NP_001617.1| v-akt murine thymoma viral oncogene ... 194 2e-47
gi|7434394|pir||JE0377 p70 S6 kinase (EC 2.7.-.-) - human >gnl|B... 194 2e-47
gi|337491|gb|AAA36585.1| rac protein kinase-beta [Homo sapiens] 194 2e-47
gi|50415318|gb|AAH78019.1| PKC-delta1 protein [Xenopus laevis] 194 2e-47
gi|32480479|dbj|BAC79119.1| protein kinase-delta1 [Xenopus laevis] 194 2e-47
gi|12643872|sp|Q9UBS0|K6B2_HUMAN Ribosomal protein S6 kinase bet... 193 3e-47
gi|25141308|ref|NP_740960.1| cyclic AMP-dependent catalytic subu... 193 3e-47
gi|4506739|ref|NP_003943.1| ribosomal protein S6 kinase, 70kDa, ... 193 3e-47
gi|33303901|gb|AAQ02464.1| ribosomal protein S6 kinase, 70kDa, p... 193 3e-47
gi|47229583|emb|CAG06779.1| unnamed protein product [Tetraodon n... 193 3e-47
gi|41055807|ref|NP_957272.1| similar to protein kinase C, beta [... 193 3e-47
gi|50285801|ref|XP_445329.1| unnamed protein product [Candida gl... 193 3e-47
gi|50415747|ref|XP_457493.1| unnamed protein product [Debaryomyc... 193 3e-47
gi|37588972|gb|AAH00094.2| RPS6KB2 protein [Homo sapiens] 193 3e-47
gi|558099|gb|AAA75571.1| protein kinase C-theta 193 4e-47
gi|5453976|ref|NP_006248.1| protein kinase C, theta [Homo sapien... 193 4e-47
gi|4157977|emb|CAA76911.1| protein kinase C [Geodia cydonium] 193 4e-47
gi|17542632|ref|NP_499860.1| tetradecanoyl Phorbol Acetate resis... 193 4e-47
gi|20072336|gb|AAH26549.1| Serum/glucocorticoid regulated kinase... 193 4e-47
gi|47939913|gb|AAH72041.1| MGC78893 protein [Xenopus laevis] 193 4e-47
gi|15787861|dbj|BAB68538.1| protein kinase C thetaII [Mus musculus] 193 4e-47
gi|303529|dbj|BAA03556.1| TPA-1 [Caenorhabditis elegans] 193 4e-47
gi|303941|dbj|BAA03268.1| protein kinase [Schizosaccharomyces po... 193 4e-47
gi|19112742|ref|NP_595950.1| protein kinase c-like 2 [Schizosacc... 193 4e-47
gi|17542634|ref|NP_499861.1| tetradecanoyl Phorbol Acetate resis... 193 4e-47
gi|46445417|gb|EAL04686.1| hypothetical protein CaO19.12357 [Can... 193 4e-47
gi|1890142|dbj|BAA18952.1| catalytic subunit of cAMP-dependent h... 193 4e-47
gi|6679353|ref|NP_032885.1| protein kinase C, theta [Mus musculu... 193 4e-47
gi|7511605|pir||T33399 protein kinase C homolog tpa-1, splice fo... 193 4e-47
gi|4432999|dbj|BAA20905.1| Rho-kinase beta [Sus scrofa] 193 4e-47
gi|10334453|emb|CAC10200.1| bA563J2.2 (protein kinase C theta ) ... 193 4e-47
gi|103330|pir||A32545 protein kinase C (EC 2.7.1.-) - fruit fly ... 193 4e-47
gi|4938231|emb|CAA28890.2| protein kinase C [Drosophila melanoga... 193 4e-47
gi|25141310|ref|NP_740962.1| cyclic AMP-dependent catalytic subu... 192 5e-47
gi|2760821|gb|AAB95270.1| serine/threonine protein kinase [Entam... 192 5e-47
gi|25141298|ref|NP_740956.1| cyclic AMP-dependent catalytic subu... 192 5e-47
gi|16266771|dbj|BAB69974.1| kinase Akt/PKB [Asterina pectinifera] 192 5e-47
gi|15231959|ref|NP_187484.1| serine/threonine protein kinase (PK... 192 5e-47
gi|25141300|ref|NP_740954.1| cyclic AMP-dependent catalytic subu... 192 5e-47
gi|41056189|ref|NP_957317.1| similar to protein kinase, cAMP dep... 192 5e-47
gi|19113977|ref|NP_593065.1| serine/threonine protein kinase [Sc... 192 5e-47
gi|6322682|ref|NP_012755.1| Involved in nutrient control of cell... 192 5e-47
gi|17508227|ref|NP_493605.1| cyclic AMP-dependent catalytic subu... 192 5e-47
gi|17557832|ref|NP_505637.1| AKT kinase (62.2 kD) (akt-1) [Caeno... 192 7e-47
gi|4558499|gb|AAD22633.1| protein kinase C; serine/threonine pro... 192 7e-47
gi|39593823|emb|CAE62116.1| Hypothetical protein CBG06155 [Caeno... 192 7e-47
gi|32480481|dbj|BAC79120.1| protein kinase-delta2 [Xenopus laevis] 192 7e-47
gi|47207651|emb|CAF91644.1| unnamed protein product [Tetraodon n... 192 9e-47
gi|30172014|gb|AAP20604.1| protein kinase C [Pichia pastoris] 192 9e-47
gi|50761134|ref|XP_418247.1| PREDICTED: similar to KIAA0561 prot... 192 9e-47
gi|31242643|ref|XP_321752.1| ENSANGP00000016916 [Anopheles gambi... 192 9e-47
gi|27807061|ref|NP_777012.1| protein kinase C, beta 1 polypeptid... 191 1e-46
gi|665540|gb|AAC46513.1| cAMP-dependent protein kinase catalytic... 191 1e-46
gi|4322296|gb|AAD16002.1| cAMP-dependent protein kinase catalyti... 191 1e-46
gi|4322300|gb|AAD16004.1| cAMP-dependent protein kinase catalyti... 191 1e-46
gi|173013|gb|AAA35166.1| cAMP-dependent protein kinase subunit (... 191 1e-46
gi|32411229|ref|XP_326095.1| hypothetical protein ( (AF264760) c... 191 1e-46
gi|2136634|pir||PC4223 rho kinase - pig (fragment) 191 1e-46
>gi|25145908|ref|NP_504599.2| protein kinase and Protein kinase
C-terminal domain and Protein kinase C, phorbol
ester/diacylglycerol binding and pleckstrin-like and
Citron-like (5G738) [Caenorhabditis elegans]
gi|21281573|gb|AAB52260.3| Hypothetical protein K08B12.5
[Caenorhabditis elegans]
Length = 1592
Score = 3061 bits (7937), Expect = 0.0
Identities = 1547/1592 (97%), Positives = 1547/1592 (97%)
Frame = -1
Query: 4779 MAEPPPDDSAPVRLKTLENIYMDGPSKKPEALSFETLIDSLICLYDECCNSTLRKEKCIA 4600
MAEPPPDDSAPVRLKTLENIYMDGPSKKPEALSFETLIDSLICLYDECCNSTLRKEKCIA
Sbjct: 1 MAEPPPDDSAPVRLKTLENIYMDGPSKKPEALSFETLIDSLICLYDECCNSTLRKEKCIA 60
Query: 4599 EFVESVKTVISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMV 4420
EFVESVKTVISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMV
Sbjct: 61 EFVESVKTVISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMV 120
Query: 4419 KRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIP 4240
KRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIP
Sbjct: 121 KRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIP 180
Query: 4239 ESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVAS 4060
ESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVAS
Sbjct: 181 ESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVAS 240
Query: 4059 NVAVGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKI 3880
NVAVGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKI
Sbjct: 241 NVAVGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKI 300
Query: 3879 MSHQDMLDFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIR 3700
MSHQDMLDFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIR
Sbjct: 301 MSHQDMLDFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIR 360
Query: 3699 DSNPPYVPEVSSPEDTSNFDVDVCEDDFTPCLQETQPPRVLAAFTGNHLPFVGFSYTHGS 3520
DSNPPYVPEVSSPEDTSNFDVDVCEDDFTPCLQETQPPRVLAAFTGNHLPFVGFSYTHGS
Sbjct: 361 DSNPPYVPEVSSPEDTSNFDVDVCEDDFTPCLQETQPPRVLAAFTGNHLPFVGFSYTHGS 420
Query: 3519 LLSDARSLTDEIRAIAQRCQGDAELMEKSVDGFMVELENEKAELVQKLKEAQTIIAQHVA 3340
LLSDARSLTDEIRAIAQRCQGDAELMEKSVDGFMVELENEKAELVQKLKEAQTIIAQHVA
Sbjct: 421 LLSDARSLTDEIRAIAQRCQGDAELMEKSVDGFMVELENEKAELVQKLKEAQTIIAQHVA 480
Query: 3339 ENPRSEEDRNYESTIAQLKDEIQILNKRLEDEALAQQQQKPKDEIVAXXXXXXXXXXERN 3160
ENPRSEEDRNYESTIAQLKDEIQILNKRLEDEALAQQQQKPKDEIVA ERN
Sbjct: 481 ENPRSEEDRNYESTIAQLKDEIQILNKRLEDEALAQQQQKPKDEIVAESEKKLKELKERN 540
Query: 3159 KQLVMEKSEIQRELDNINDHLDQVLVEKATVVQQRDDMQAELADVGDSLLTEKDSVKRLQ 2980
KQLVMEKSEIQRELDNINDHLDQVLVEKATVVQQRDDMQAELADVGDSLLTEKDSVKRLQ
Sbjct: 541 KQLVMEKSEIQRELDNINDHLDQVLVEKATVVQQRDDMQAELADVGDSLLTEKDSVKRLQ 600
Query: 2979 DEAEKAKKQVADFXXXXXXXXXXXXXXXXKQEEVTIEARKSVETDDHLSEEVVAAKNTIA 2800
DEAEKAKKQVADF KQEEVTIEARKSVETDDHLSEEVVAAKNTIA
Sbjct: 601 DEAEKAKKQVADFEEKLKEIETEKIALIKKQEEVTIEARKSVETDDHLSEEVVAAKNTIA 660
Query: 2799 SLQATNEERETEIKKLKQRMDEERASHTAQSEQEMKQLEAHYERAQKMLQDNVEQMNVEN 2620
SLQATNEERETEIKKLKQRMDEERASHTAQSEQEMKQLEAHYERAQKMLQDNVEQMNVEN
Sbjct: 661 SLQATNEERETEIKKLKQRMDEERASHTAQSEQEMKQLEAHYERAQKMLQDNVEQMNVEN 720
Query: 2619 RGLRDEIEKLSQQMAALPRGGLNEQQLHEIFNWVSEEKATREEMENLTRKITGEVESLKN 2440
RGLRDEIEKLSQQMAALPRGGLNEQQLHEIFNWVSEEKATREEMENLTRKITGEVESLKN
Sbjct: 721 RGLRDEIEKLSQQMAALPRGGLNEQQLHEIFNWVSEEKATREEMENLTRKITGEVESLKN 780
Query: 2439 NSPLTTSNYIQNTPSGWGSRRMNNVARKDGLDLQRQLQAEIDAKLKLKAELKNSQEQYLT 2260
NSPLTTSNYIQNTPSGWGSRRMNNVARKDGLDLQRQLQAEIDAKLKLKAELKNSQEQYLT
Sbjct: 781 NSPLTTSNYIQNTPSGWGSRRMNNVARKDGLDLQRQLQAEIDAKLKLKAELKNSQEQYLT 840
Query: 2259 SAARLDDTEKRMASLMREVAMLKQQKNIENSSDSAFSSTMGRGDLMISMNNDYEMSNSSL 2080
SAARLDDTEKRMASLMREVAMLKQQKNIENSSDSAFSSTMGRGDLMISMNNDYEMSNSSL
Sbjct: 841 SAARLDDTEKRMASLMREVAMLKQQKNIENSSDSAFSSTMGRGDLMISMNNDYEMSNSSL 900
Query: 2079 MRQEMISRQSTPSYENAILLHDHQVPKRVDDLRYKQKPMKTASGIFSPVSISAMERGHNF 1900
MRQEMISRQSTPSYENAILLHDHQVPKRVDDLRYKQKPMKTASGIFSPVSISAMERGHNF
Sbjct: 901 MRQEMISRQSTPSYENAILLHDHQVPKRVDDLRYKQKPMKTASGIFSPVSISAMERGHNF 960
Query: 1899 ERMKIKTPTKCGHCTSILIGLDRQGLFCQSCQYACHVSCAERVSQSCPVPEEERRPLGID 1720
ERMKIKTPTKCGHCTSILIGLDRQGLFCQSCQYACHVSCAERVSQSCPVPEEERRPLGID
Sbjct: 961 ERMKIKTPTKCGHCTSILIGLDRQGLFCQSCQYACHVSCAERVSQSCPVPEEERRPLGID 1020
Query: 1719 PTRGVGTAYEGLVKTPRAGGVRKGWQTAYVVVCDFKLYLYDCTVDRQNKMQDVKNEIRLV 1540
PTRGVGTAYEGLVKTPRAGGVRKGWQTAYVVVCDFKLYLYDCTVDRQNKMQDVKNEIRLV
Sbjct: 1021 PTRGVGTAYEGLVKTPRAGGVRKGWQTAYVVVCDFKLYLYDCTVDRQNKMQDVKNEIRLV 1080
Query: 1539 LDMRDPDFTVCGVSEADVIHAQKGDIPKIFRVTTTQILNXXXXXXXXSKFYTLFMAETEE 1360
LDMRDPDFTVCGVSEADVIHAQKGDIPKIFRVTTTQILN SKFYTLFMAETEE
Sbjct: 1081 LDMRDPDFTVCGVSEADVIHAQKGDIPKIFRVTTTQILNSSSEYSSSSKFYTLFMAETEE 1140
Query: 1359 EKRKWVVALSELKTLLRRSKLADRKAFLVKEVFDVTTLPSIRVAQCCAIIDRSKIVIGFS 1180
EKRKWVVALSELKTLLRRSKLADRKAFLVKEVFDVTTLPSIRVAQCCAIIDRSKIVIGFS
Sbjct: 1141 EKRKWVVALSELKTLLRRSKLADRKAFLVKEVFDVTTLPSIRVAQCCAIIDRSKIVIGFS 1200
Query: 1179 DHGLYCIEISRQLLIPVGGEKENKQRCVETVEYDEAEQLLMMIVGPAKDRHVRIVPSAAL 1000
DHGLYCIEISRQLLIPVGGEKENKQRCVETVEYDEAEQLLMMIVGPAKDRHVRIVPSAAL
Sbjct: 1201 DHGLYCIEISRQLLIPVGGEKENKQRCVETVEYDEAEQLLMMIVGPAKDRHVRIVPSAAL 1260
Query: 999 DGRDLKWIKVNDTKGCHLLAVGTNNPGGRAGFFAVAFKKSVTIFQIDRSEKRHKKWKDLA 820
DGRDLKWIKVNDTKGCHLLAVGTNNPGGRAGFFAVAFKKSVTIFQIDRSEKRHKKWKDLA
Sbjct: 1261 DGRDLKWIKVNDTKGCHLLAVGTNNPGGRAGFFAVAFKKSVTIFQIDRSEKRHKKWKDLA 1320
Query: 819 MPGTPQSIAIFNGRLYVGFSHSFRSWSLVGVDSSPVGSGDASGAVLQHISLVNMEDTSLQ 640
MPGTPQSIAIFNGRLYVGFSHSFRSWSLVGVDSSPVGSGDASGAVLQHISLVNMEDTSLQ
Sbjct: 1321 MPGTPQSIAIFNGRLYVGFSHSFRSWSLVGVDSSPVGSGDASGAVLQHISLVNMEDTSLQ 1380
Query: 639 FLNQQTSYEAKLIVNVPGSPDEYLLVFNMIGLYVNEMGRRSRLPEVMFPTQAKYFAYHEP 460
FLNQQTSYEAKLIVNVPGSPDEYLLVFNMIGLYVNEMGRRSRLPEVMFPTQAKYFAYHEP
Sbjct: 1381 FLNQQTSYEAKLIVNVPGSPDEYLLVFNMIGLYVNEMGRRSRLPEVMFPTQAKYFAYHEP 1440
Query: 459 YLCVFSENEVDIFNVTLAEWVQTINLRSAKPLSGDGILSTCLCNDSPIFVLLQNVLQDQD 280
YLCVFSENEVDIFNVTLAEWVQTINLRSAKPLSGDGILSTCLCNDSPIFVLLQNVLQDQD
Sbjct: 1441 YLCVFSENEVDIFNVTLAEWVQTINLRSAKPLSGDGILSTCLCNDSPIFVLLQNVLQDQD 1500
Query: 279 SIEVPVNLASGSTDGXXXXXXXXXXXTIGKDDRSASERRSHIQISTPSDFMHIVHMGPAP 100
SIEVPVNLASGSTDG TIGKDDRSASERRSHIQISTPSDFMHIVHMGPAP
Sbjct: 1501 SIEVPVNLASGSTDGRKVTRRKFTFRTIGKDDRSASERRSHIQISTPSDFMHIVHMGPAP 1560
Query: 99 VMELQQNFIDLQSNHSHTSSDKDSLNRSVNND 4
VMELQQNFIDLQSNHSHTSSDKDSLNRSVNND
Sbjct: 1561 VMELQQNFIDLQSNHSHTSSDKDSLNRSVNND 1592
>gi|7505496|pir||T25808 hypothetical protein K08B12.5 - Caenorhabditis
elegans
Length = 1548
Score = 2930 bits (7596), Expect = 0.0
Identities = 1498/1592 (94%), Positives = 1500/1592 (94%)
Frame = -1
Query: 4779 MAEPPPDDSAPVRLKTLENIYMDGPSKKPEALSFETLIDSLICLYDECCNSTLRKEKCIA 4600
MAEPPPDDSAPVRLKTLENIYMDGPSKKPEALSFETLIDSLICLYDECCNSTLRKEKCIA
Sbjct: 1 MAEPPPDDSAPVRLKTLENIYMDGPSKKPEALSFETLIDSLICLYDECCNSTLRKEKCIA 60
Query: 4599 EFVESVKTVISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMV 4420
EFVESVKTVISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMV
Sbjct: 61 EFVESVKTVISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMV 120
Query: 4419 KRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIP 4240
KRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIP
Sbjct: 121 KRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIP 180
Query: 4239 ESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVAS 4060
ESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVAS
Sbjct: 181 ESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVAS 240
Query: 4059 NVAVGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKI 3880
NVAVGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKI
Sbjct: 241 NVAVGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKI 300
Query: 3879 MSHQDMLDFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIR 3700
MSHQDMLDFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIR
Sbjct: 301 MSHQDMLDFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIR 360
Query: 3699 DSNPPYVPEVSSPEDTSNFDVDVCEDDFTPCLQETQPPRVLAAFTGNHLPFVGFSYTHGS 3520
DSNPPYVPEVSSPEDTSNFDVDVCEDDFTPC ETQPPRVLAAFTGNHLPFVGFSYTHGS
Sbjct: 361 DSNPPYVPEVSSPEDTSNFDVDVCEDDFTPC--ETQPPRVLAAFTGNHLPFVGFSYTHGS 418
Query: 3519 LLSDARSLTDEIRAIAQRCQGDAELMEKSVDGFMVELENEKAELVQKLKEAQTIIAQHVA 3340
LLSDARSLTDEIRAIAQRCQGDAELMEKSVDGFMVELENEKAELVQKLKEAQTIIAQHVA
Sbjct: 419 LLSDARSLTDEIRAIAQRCQGDAELMEKSVDGFMVELENEKAELVQKLKEAQTIIAQHVA 478
Query: 3339 ENPRSEEDRNYESTIAQLKDEIQILNKRLEDEALAQQQQKPKDEIVAXXXXXXXXXXERN 3160
ENPRSEEDRNYESTIAQLKDEIQILNKRLEDEALAQQQQKPKDEIVA ERN
Sbjct: 479 ENPRSEEDRNYESTIAQLKDEIQILNKRLEDEALAQQQQKPKDEIVAESEKKLKELKERN 538
Query: 3159 KQLVMEKSEIQRELDNINDHLDQVLVEKATVVQQRDDMQAELADVGDSLLTEKDSVKRLQ 2980
KQLVMEKSEIQRELDNINDHLDQVLVEKATVVQQRDDMQAELADVGDSLLTEKDSVKRLQ
Sbjct: 539 KQLVMEKSEIQRELDNINDHLDQVLVEKATVVQQRDDMQAELADVGDSLLTEKDSVKRLQ 598
Query: 2979 DEAEKAKKQVADFXXXXXXXXXXXXXXXXKQEEVTIEARKSVETDDHLSEEVVAAKNTIA 2800
DEAEKAKKQVADF KQEEVTIEARKSVETDDHLSEEVVAAKNTIA
Sbjct: 599 DEAEKAKKQVADFEEKLKEIETEKIALIKKQEEVTIEARKSVETDDHLSEEVVAAKNTIA 658
Query: 2799 SLQATNEERETEIKKLKQRMDEERASHTAQSEQEMKQLEAHYERAQKMLQDNVEQMNVEN 2620
SLQATNEERETEIKKLKQRMDEERASHTAQSEQEMKQLEAHYERAQKMLQDNVEQMNVEN
Sbjct: 659 SLQATNEERETEIKKLKQRMDEERASHTAQSEQEMKQLEAHYERAQKMLQDNVEQMNVEN 718
Query: 2619 RGLRDEIEKLSQQMAALPRGGLNEQQLHEIFNWVSEEKATREEMENLTRKITGEVESLKN 2440
RGLRDEIEKLSQQMAALPRGGLNEQQLHEIFNWVSEEKATREEMENLTRKITGEVESLKN
Sbjct: 719 RGLRDEIEKLSQQMAALPRGGLNEQQLHEIFNWVSEEKATREEMENLTRKITGEVESLKN 778
Query: 2439 NSPLTTSNYIQNTPSGWGSRRMNNVARKDGLDLQRQLQAEIDAKLKLKAELKNSQEQYLT 2260
NSPLTTSNYIQNTPSGWGSRRMNNVARKDGLDLQRQLQAEIDAKLKLKAELKNSQEQYLT
Sbjct: 779 NSPLTTSNYIQNTPSGWGSRRMNNVARKDGLDLQRQLQAEIDAKLKLKAELKNSQEQYLT 838
Query: 2259 SAARLDDTEKRMASLMREVAMLKQQKNIENSSDSAFSSTMGRGDLMISMNNDYEMSNSSL 2080
SAARLDDTEKRMASLMREVAMLKQQKNIENSSDSAFSSTMGRGDLMISMNNDYEMSNSSL
Sbjct: 839 SAARLDDTEKRMASLMREVAMLKQQKNIENSSDSAFSSTMGRGDLMISMNNDYEMSNSSL 898
Query: 2079 MRQEMISRQSTPSYENAILLHDHQVPKRVDDLRYKQKPMKTASGIFSPVSISAMERGHNF 1900
MRQEMISRQSTPSYENAILLHDHQVPKRVDDLRYKQKPMKTASGIFSPVSISAMERGHNF
Sbjct: 899 MRQEMISRQSTPSYENAILLHDHQVPKRVDDLRYKQKPMKTASGIFSPVSISAMERGHNF 958
Query: 1899 ERMKIKTPTKCGHCTSILIGLDRQGLFCQSCQYACHVSCAERVSQSCPVPEEERRPLGID 1720
ERMKIKTPTKCGHCTSILIGLDRQGLFCQSCQYACHVSCAERVSQSCPVPEEERRPLG+
Sbjct: 959 ERMKIKTPTKCGHCTSILIGLDRQGLFCQSCQYACHVSCAERVSQSCPVPEEERRPLGM- 1017
Query: 1719 PTRGVGTAYEGLVKTPRAGGVRKGWQTAYVVVCDFKLYLYDCTVDRQNKMQDVKNEIRLV 1540
+R QNKMQDVKNEIRLV
Sbjct: 1018 --------------------IRHA---------------------EQNKMQDVKNEIRLV 1036
Query: 1539 LDMRDPDFTVCGVSEADVIHAQKGDIPKIFRVTTTQILNXXXXXXXXSKFYTLFMAETEE 1360
LDMRDPDFTVCGVSEADVIHAQKGDIPKIFRVTTTQILN SKFYTLFMAETEE
Sbjct: 1037 LDMRDPDFTVCGVSEADVIHAQKGDIPKIFRVTTTQILNSSSEYSSSSKFYTLFMAETEE 1096
Query: 1359 EKRKWVVALSELKTLLRRSKLADRKAFLVKEVFDVTTLPSIRVAQCCAIIDRSKIVIGFS 1180
EKRKWVVALSELKTLLRRSKLADRKAFLVKEVFDVTTLPSIRVAQCCAIIDRSKIVIGFS
Sbjct: 1097 EKRKWVVALSELKTLLRRSKLADRKAFLVKEVFDVTTLPSIRVAQCCAIIDRSKIVIGFS 1156
Query: 1179 DHGLYCIEISRQLLIPVGGEKENKQRCVETVEYDEAEQLLMMIVGPAKDRHVRIVPSAAL 1000
DHGLYCIEISRQLLIPVGGEKENKQRCVETVEYDEAEQLLMMIVGPAKDRHVRIVPSAAL
Sbjct: 1157 DHGLYCIEISRQLLIPVGGEKENKQRCVETVEYDEAEQLLMMIVGPAKDRHVRIVPSAAL 1216
Query: 999 DGRDLKWIKVNDTKGCHLLAVGTNNPGGRAGFFAVAFKKSVTIFQIDRSEKRHKKWKDLA 820
DGRDLKWIKVNDTKGCHLLAVGTNNPGGRAGFFAVAFKKSVTIFQIDRSEKRHKKWKDLA
Sbjct: 1217 DGRDLKWIKVNDTKGCHLLAVGTNNPGGRAGFFAVAFKKSVTIFQIDRSEKRHKKWKDLA 1276
Query: 819 MPGTPQSIAIFNGRLYVGFSHSFRSWSLVGVDSSPVGSGDASGAVLQHISLVNMEDTSLQ 640
MPGTPQSIAIFNGRLYVGFSHSFRSWSLVGVDSSPVGSGDASGAVLQHISLVNMEDTSLQ
Sbjct: 1277 MPGTPQSIAIFNGRLYVGFSHSFRSWSLVGVDSSPVGSGDASGAVLQHISLVNMEDTSLQ 1336
Query: 639 FLNQQTSYEAKLIVNVPGSPDEYLLVFNMIGLYVNEMGRRSRLPEVMFPTQAKYFAYHEP 460
FLNQQTSYEAKLIVNVPGSPDEYLLVFNMIGLYVNEMGRRSRLPEVMFPTQAKYFAYHEP
Sbjct: 1337 FLNQQTSYEAKLIVNVPGSPDEYLLVFNMIGLYVNEMGRRSRLPEVMFPTQAKYFAYHEP 1396
Query: 459 YLCVFSENEVDIFNVTLAEWVQTINLRSAKPLSGDGILSTCLCNDSPIFVLLQNVLQDQD 280
YLCVFSENEVDIFNVTLAEWVQTINLRSAKPLSGDGILSTCLCNDSPIFVLLQNVLQDQD
Sbjct: 1397 YLCVFSENEVDIFNVTLAEWVQTINLRSAKPLSGDGILSTCLCNDSPIFVLLQNVLQDQD 1456
Query: 279 SIEVPVNLASGSTDGXXXXXXXXXXXTIGKDDRSASERRSHIQISTPSDFMHIVHMGPAP 100
SIEVPVNLASGSTDG TIGKDDRSASERRSHIQISTPSDFMHIVHMGPAP
Sbjct: 1457 SIEVPVNLASGSTDGRKVTRRKFTFRTIGKDDRSASERRSHIQISTPSDFMHIVHMGPAP 1516
Query: 99 VMELQQNFIDLQSNHSHTSSDKDSLNRSVNND 4
VMELQQNFIDLQSNHSHTSSDKDSLNRSVNND
Sbjct: 1517 VMELQQNFIDLQSNHSHTSSDKDSLNRSVNND 1548
>gi|39594275|emb|CAE71853.1| Hypothetical protein CBG18897
[Caenorhabditis briggsae]
Length = 1586
Score = 2888 bits (7487), Expect = 0.0
Identities = 1445/1592 (90%), Positives = 1494/1592 (93%)
Frame = -1
Query: 4779 MAEPPPDDSAPVRLKTLENIYMDGPSKKPEALSFETLIDSLICLYDECCNSTLRKEKCIA 4600
MA+PPPDDSAPVRLK LENIYMDGPSK+PEALSFETLIDSLICLYDECCNSTLRKEKCIA
Sbjct: 1 MADPPPDDSAPVRLKDLENIYMDGPSKRPEALSFETLIDSLICLYDECCNSTLRKEKCIA 60
Query: 4599 EFVESVKTVISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMV 4420
EFVESVKTVI KAKKLRL RDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMV
Sbjct: 61 EFVESVKTVIGKAKKLRLGRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMV 120
Query: 4419 KRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIP 4240
KRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIP
Sbjct: 121 KRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIP 180
Query: 4239 ESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVAS 4060
ESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRIL DGSVAS
Sbjct: 181 ESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILPDGSVAS 240
Query: 4059 NVAVGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKI 3880
NVAVGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKI
Sbjct: 241 NVAVGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKI 300
Query: 3879 MSHQDMLDFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIR 3700
MSHQDMLDFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQ HPFFEGIDWNTIR
Sbjct: 301 MSHQDMLDFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQSHPFFEGIDWNTIR 360
Query: 3699 DSNPPYVPEVSSPEDTSNFDVDVCEDDFTPCLQETQPPRVLAAFTGNHLPFVGFSYTHGS 3520
DS+PPY PEVSSPEDTSNFDVDVCEDDFTPC ETQPPRVLAAFTGNHLPFVGFSYTHGS
Sbjct: 361 DSSPPYKPEVSSPEDTSNFDVDVCEDDFTPC--ETQPPRVLAAFTGNHLPFVGFSYTHGS 418
Query: 3519 LLSDARSLTDEIRAIAQRCQGDAELMEKSVDGFMVELENEKAELVQKLKEAQTIIAQHVA 3340
LLSDARSLTDEIRAIAQRCQGDAELMEKSVDGFMVELENEKAELVQKLKEAQ IIAQHVA
Sbjct: 419 LLSDARSLTDEIRAIAQRCQGDAELMEKSVDGFMVELENEKAELVQKLKEAQIIIAQHVA 478
Query: 3339 ENPRSEEDRNYESTIAQLKDEIQILNKRLEDEALAQQQQKPKDEIVAXXXXXXXXXXERN 3160
ENPR+ EDRNYE+TIAQLKDEIQILNKRLEDEA+AQQQQKPKDEIV ERN
Sbjct: 479 ENPRTGEDRNYEATIAQLKDEIQILNKRLEDEAVAQQQQKPKDEIVVESEKKLKELKERN 538
Query: 3159 KQLVMEKSEIQRELDNINDHLDQVLVEKATVVQQRDDMQAELADVGDSLLTEKDSVKRLQ 2980
KQLVMEK EIQRELDNINDHLDQVLVEKATVVQQRDDMQAEL D+GD+LL+EKD+VKRLQ
Sbjct: 539 KQLVMEKGEIQRELDNINDHLDQVLVEKATVVQQRDDMQAELTDIGDALLSEKDAVKRLQ 598
Query: 2979 DEAEKAKKQVADFXXXXXXXXXXXXXXXXKQEEVTIEARKSVETDDHLSEEVVAAKNTIA 2800
+E+EKAKKQ + KQEEVT+EARKSVETDDHLSEEVVAAK IA
Sbjct: 599 EESEKAKKQTTELEEKLKDVEAEKVILIKKQEEVTLEARKSVETDDHLSEEVVAAKKNIA 658
Query: 2799 SLQATNEERETEIKKLKQRMDEERASHTAQSEQEMKQLEAHYERAQKMLQDNVEQMNVEN 2620
+LQ NEE+E EIKKLKQRM+EERA+HTAQSEQEMKQLEAHYERAQKMLQDNVEQMNVEN
Sbjct: 659 TLQTANEEKEAEIKKLKQRMEEERANHTAQSEQEMKQLEAHYERAQKMLQDNVEQMNVEN 718
Query: 2619 RGLRDEIEKLSQQMAALPRGGLNEQQLHEIFNWVSEEKATREEMENLTRKITGEVESLKN 2440
RGLRDEIEKLSQQMAALPRG L EQQL E+FNWV+EEKATREEMENLTRKITGEVESLKN
Sbjct: 719 RGLRDEIEKLSQQMAALPRGALTEQQLLELFNWVNEEKATREEMENLTRKITGEVESLKN 778
Query: 2439 NSPLTTSNYIQNTPSGWGSRRMNNVARKDGLDLQRQLQAEIDAKLKLKAELKNSQEQYLT 2260
NSPLTTSNYIQNTPSGWGSRRMNNVARKDGLDLQRQLQAEIDAKLKLK+ELKNSQEQYLT
Sbjct: 779 NSPLTTSNYIQNTPSGWGSRRMNNVARKDGLDLQRQLQAEIDAKLKLKSELKNSQEQYLT 838
Query: 2259 SAARLDDTEKRMASLMREVAMLKQQKNIENSSDSAFSSTMGRGDLMISMNNDYEMSNSSL 2080
+ ARL+DTEKRMASLMREV MLKQQK+ + S+DSAFSS++GRGDLMISMNNDYEMSNSSL
Sbjct: 839 ATARLEDTEKRMASLMREVTMLKQQKHTDISTDSAFSSSIGRGDLMISMNNDYEMSNSSL 898
Query: 2079 MRQEMISRQSTPSYENAILLHDHQVPKRVDDLRYKQKPMKTASGIFSPVSISAMERGHNF 1900
MRQEMISRQSTPSYENAILLHDHQ PKRVDDLRYKQKPMK +SGIFSP S+S MERGHNF
Sbjct: 899 MRQEMISRQSTPSYENAILLHDHQAPKRVDDLRYKQKPMKASSGIFSPASVSTMERGHNF 958
Query: 1899 ERMKIKTPTKCGHCTSILIGLDRQGLFCQSCQYACHVSCAERVSQSCPVPEEERRPLGID 1720
ERMKIKTPTKCGHCTSILIGLDRQGL+CQSCQYACHVSCAERVSQSCPVPEEERRPLGID
Sbjct: 959 ERMKIKTPTKCGHCTSILIGLDRQGLYCQSCQYACHVSCAERVSQSCPVPEEERRPLGID 1018
Query: 1719 PTRGVGTAYEGLVKTPRAGGVRKGWQTAYVVVCDFKLYLYDCTVDRQNKMQDVKNEIRLV 1540
PTRGVGTAYEGLVKTPR GGVRKGWQTAYVVVCDFKLYLYDCTVD+QNKMQDVKNEIRLV
Sbjct: 1019 PTRGVGTAYEGLVKTPRIGGVRKGWQTAYVVVCDFKLYLYDCTVDKQNKMQDVKNEIRLV 1078
Query: 1539 LDMRDPDFTVCGVSEADVIHAQKGDIPKIFRVTTTQILNXXXXXXXXSKFYTLFMAETEE 1360
LDMRDPDFTVCGVSEADVIHAQK D+PKIFRVTTTQI+N SKFYTLFMAETEE
Sbjct: 1079 LDMRDPDFTVCGVSEADVIHAQKNDVPKIFRVTTTQIMNSSSEYSSSSKFYTLFMAETEE 1138
Query: 1359 EKRKWVVALSELKTLLRRSKLADRKAFLVKEVFDVTTLPSIRVAQCCAIIDRSKIVIGFS 1180
EKRKWVVALSELKTLLRRSKLADRKAF+VKEVFDVTTLPSIRVAQCCAIIDRSK+VIGFS
Sbjct: 1139 EKRKWVVALSELKTLLRRSKLADRKAFVVKEVFDVTTLPSIRVAQCCAIIDRSKVVIGFS 1198
Query: 1179 DHGLYCIEISRQLLIPVGGEKENKQRCVETVEYDEAEQLLMMIVGPAKDRHVRIVPSAAL 1000
DHGLYC+EI+RQ+LIPVGGEKENKQRCVETVEYDEAEQLL+MIVGPAKDRHVRIVPSAAL
Sbjct: 1199 DHGLYCVEINRQVLIPVGGEKENKQRCVETVEYDEAEQLLLMIVGPAKDRHVRIVPSAAL 1258
Query: 999 DGRDLKWIKVNDTKGCHLLAVGTNNPGGRAGFFAVAFKKSVTIFQIDRSEKRHKKWKDLA 820
DGRDLKWIKVNDTKGCHL+AVGTNNP GRAG+FAVAFKKSVTIFQIDRSEKRHKKWKDLA
Sbjct: 1259 DGRDLKWIKVNDTKGCHLMAVGTNNPSGRAGYFAVAFKKSVTIFQIDRSEKRHKKWKDLA 1318
Query: 819 MPGTPQSIAIFNGRLYVGFSHSFRSWSLVGVDSSPVGSGDASGAVLQHISLVNMEDTSLQ 640
MPGTPQS+AIFNGRLYVGF HSFRSWSL D P+ SGD G +LQHISL+NMEDTSLQ
Sbjct: 1319 MPGTPQSMAIFNGRLYVGFPHSFRSWSLASAD--PLASGD--GIILQHISLINMEDTSLQ 1374
Query: 639 FLNQQTSYEAKLIVNVPGSPDEYLLVFNMIGLYVNEMGRRSRLPEVMFPTQAKYFAYHEP 460
FLNQ T YEAKLIVN+PGSPDEYLLVFNMIGLYVNEMGRRSRLPEVMFPTQAKYF YHEP
Sbjct: 1375 FLNQHTQYEAKLIVNLPGSPDEYLLVFNMIGLYVNEMGRRSRLPEVMFPTQAKYFTYHEP 1434
Query: 459 YLCVFSENEVDIFNVTLAEWVQTINLRSAKPLSGDGILSTCLCNDSPIFVLLQNVLQDQD 280
YLCVFSENEVDIFNVTLAEWVQTINLRSAKPLS DGILS CLCNDSPIFVLLQNVLQDQD
Sbjct: 1435 YLCVFSENEVDIFNVTLAEWVQTINLRSAKPLSNDGILSMCLCNDSPIFVLLQNVLQDQD 1494
Query: 279 SIEVPVNLASGSTDGXXXXXXXXXXXTIGKDDRSASERRSHIQISTPSDFMHIVHMGPAP 100
SIEVPVNLASGSTDG T GKDDRSASERRSHIQISTPSDFMH+VHMGPAP
Sbjct: 1495 SIEVPVNLASGSTDGRKVTRRKFTFKTHGKDDRSASERRSHIQISTPSDFMHVVHMGPAP 1554
Query: 99 VMELQQNFIDLQSNHSHTSSDKDSLNRSVNND 4
ELQ+NFIDLQSNHSHTSSDKDSLNRSVNND
Sbjct: 1555 ATELQKNFIDLQSNHSHTSSDKDSLNRSVNND 1586
>gi|29373942|emb|CAD57746.1| CDC42 binding protein kinase alpha
(DMPK-like) [Homo sapiens]
Length = 1638
Score = 1049 bits (2712), Expect = 0.0
Identities = 632/1606 (39%), Positives = 925/1606 (57%), Gaps = 50/1606 (3%)
Frame = -1
Query: 4755 SAPVRLKTLENIYMDGPSK-KPEALSFETLIDSLICLYDECCNSTLRKEKCIAEFVESVK 4579
S VRL+ LE +DGP++ + S ETL+D LICLYDEC NS LR+EK I E++E K
Sbjct: 2 SGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWAK 61
Query: 4578 TVISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETAC 4399
SK K++RL R+DFE+LKVIG+GAFGEVAVV+++ +++AMKILNKWEM+KRAETAC
Sbjct: 62 PFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETAC 121
Query: 4398 FREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFY 4219
FREERDVLV GD +WIT LHYAFQD+ NLY VMDYY+GGD+LTLLSKF D +PE MA+FY
Sbjct: 122 FREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFY 181
Query: 4218 IAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASNVAVGTP 4039
+AEMV+AIDS+H+L YVHRD+KPDN+L+DM GHIRLADFGSCL+++ DG+V S+VAVGTP
Sbjct: 182 LAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTP 241
Query: 4038 DYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDML 3859
DYISPEIL+AMEDG+GRYG ECDWWSLG+CMYEMLYG TPFY+E LV+TYGKIM+H++
Sbjct: 242 DYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERF 301
Query: 3858 DFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIRDSNPPYV 3679
FP D VSE AKDLIR+LICS + R G+NG+ DF+ HPFF GIDW+ IR+ PY+
Sbjct: 302 QFPAQVTD--VSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYI 359
Query: 3678 PEVSSPEDTSNFDVDVCEDDFTPCLQ--ETQPPRVLAAFTGNHLPFVGFSYTHGSLLSDA 3505
PEVSSP DTSNFDVD DD CL+ ET PP AF+G+HLPFVGF+YT +LSD
Sbjct: 360 PEVSSPTDTSNFDVD---DD---CLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDR 413
Query: 3504 RSL-------TDEIRAIAQRCQGDAELMEKSVDGFMVELENEKAELVQKLKEA-QTIIA- 3352
L + ++ QR D L ++ + + LE EK EL +KL+E+ QT+ A
Sbjct: 414 SCLRVTAGPTSLDLDVNVQRTL-DNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQAL 472
Query: 3351 QHVAENPRSEEDRNYESTIAQLKDEIQILNKRLEDEALAQQQQKPKDEIVAXXXXXXXXX 3172
Q+ + ++ E I LK+EI+ L K++ + + +QQ +
Sbjct: 473 QYSTVDGPLTASKDLE--IKNLKEEIEKLRKQVTESSHLEQQLE---------------- 514
Query: 3171 XERNKQLVMEKSEIQRELDNINDHLDQVLVEKATVVQQRDDMQAELADVGDSLLTEKDSV 2992
E + +++ELD+ + + T+ Q+R+D+ +L ++L E
Sbjct: 515 ---------EANAVRQELDDAFRQIKAYEKQIKTLQQEREDLN-KLEVHTEALAAEASKD 564
Query: 2991 KRLQDEAEKAKKQVADFXXXXXXXXXXXXX---XXXKQEEVT-----IEARKSVETDDHL 2836
++L++++E KQ+ + Q+E+T +E +KS+ ++ L
Sbjct: 565 RKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEITKLKTDLE-KKSIFYEEEL 623
Query: 2835 SEEVVAAKNTIASLQATNEERE-------TEIKKLKQRMDEERASHTAQSEQEMKQLEAH 2677
S+ N I +L+ + E EI LK ++++ R ++ E+ + +
Sbjct: 624 SKREGIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQ 683
Query: 2676 YERAQKMLQDN--------------VEQMNVENRGLRDEIEKLSQQMAALPRGGLNEQQL 2539
YER + +L + E +++ N+ L +E++ L+ + ++ E Q+
Sbjct: 684 YEREKVLLTEENKKLTSELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHW---EAQI 740
Query: 2538 HEIFNWVSEEKATREEMENLTRKITGEVESLKNNSPLTTSNYIQNTPSGWGSRRMNNVAR 2359
EI WVS+EK R ++ L K+T E+E+L+N+S T + T W RR +
Sbjct: 741 TEIIQWVSDEKDARGYLQALASKMTEELEALRNSSLGTRA-----TDMPWKMRRFAKLDM 795
Query: 2358 KDGLDLQRQLQAEIDAKLKLKAELKNSQEQYLTSAARLDDTEKRMASLMREVAMLKQQKN 2179
L+LQ L AEI AK ++ EL + + + +L D+EK+ L+ E+ L +
Sbjct: 796 SARLELQSALDAEIRAKQAIQEELNKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTE 855
Query: 2178 IENSSDSAFSSTMGRGDLMISMNNDYEMSNSSLMRQEMISRQSTPSYENAILLHDHQVPK 1999
E S+ + + +N + +L + E + STP +
Sbjct: 856 -ELRSEKGIEHQDSQHSFLAFLNTPTD----ALDQFETVD--STP------------LSV 896
Query: 1998 RVDDLRYKQKPMKTASGIFSPVSISAMERGHNFERMKIKTPTKCGHCTSILIGLDRQGLF 1819
LR K P T F P + H F TPTKC CTS+++GL RQG
Sbjct: 897 HTPTLRKKGCPGSTG---FPP-----KRKTHQFFVKSFTTPTKCHQCTSLMVGLIRQGCS 948
Query: 1818 CQSCQYACHVSCAERVSQSCPVPEEERR-PLGIDPTRGVGTAYEGLVKTPRAGGVRKGWQ 1642
C+ C ++CH++C + +CPVP E+ + PLGIDP +G+GTAYEG V+ P+ GV+KGWQ
Sbjct: 949 CEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPKPAGVKKGWQ 1008
Query: 1641 TAYVVVCDFKLYLYDCTVDRQNKMQDVKNEIRLVLDMRDPDFTVCGVSEADVIHAQKGDI 1462
A +VCDFKL+LYD + ++ V I V+DMRD +F+V V +DVIHA + DI
Sbjct: 1009 RALAIVCDFKLFLYDIAEGKASQPSVV---ISQVIDMRDEEFSVSSVLASDVIHASRKDI 1065
Query: 1461 PKIFRVTTTQILNXXXXXXXXSKFYTLFMAETEEEKRKWVVALSELKTLLRRSKLADRKA 1282
P IFRVT +Q+ +K L +A+TE EK KWV LSEL +L+++K DR
Sbjct: 1066 PCIFRVTASQL------SASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSV 1119
Query: 1281 FLVKEVFDVTTLPSIRVAQCCAIIDRSKIVIGFSDHGLYCIEISRQLLIPVGGEKENKQR 1102
++ KE +D +TLP I+ Q AIID +I +G ++ GL+ + +++ +I VG K+
Sbjct: 1120 YVPKEAYD-STLPLIKTTQAAAIIDHERIALG-NEEGLFVVHVTKDEIIRVGDNKK---- 1173
Query: 1101 CVETVEYDEAEQLLMMIVGPAKDRHVRIVPSAALDGRDLKWIKVNDTKGCHLLAVGTNNP 922
+ +E +QL+ +I G ++RHVR+ P +ALDGR+ + K+++TKGC + G
Sbjct: 1174 -IHQIELIPNDQLVAVISG--RNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRH 1230
Query: 921 GGRAGFFAVAFKKSVTIFQIDRSEKRHKKWKDLAMPGTPQSIAIFNGRLYVGFSHSFRSW 742
G VA K+ V +++ +S+ RH+K+K++ +P Q +AIF+ +L VGF F +
Sbjct: 1231 GALT-CLCVAMKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRY 1289
Query: 741 SLVGVDSSPVGSGDASGAVLQHISLVNMEDTSLQFLNQQTSYEAKLIVNVPGSPDEYLLV 562
L G + +P S+++ D +L F+ Q I V S EYLL
Sbjct: 1290 PLNG-EGNPY-------------SMLHSNDHTLSFIAHQPM---DAICAVEISSKEYLLC 1332
Query: 561 FNMIGLYVNEMGRRSRLPEVMFPTQAKYFAYHEPYLCVFSENEVDIFNVTLAEWVQTINL 382
FN IG+Y + GRRSR E+M+P Y+ PYL V+SEN VDIF+V EW+QT+ L
Sbjct: 1333 FNSIGIYTDCQGRRSRQQELMWPANPSSCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPL 1392
Query: 381 RSAKPLSGDGILSTCLCNDSPIFVLLQNVLQDQDSIEVPVNLASGSTDGXXXXXXXXXXX 202
+ +PL+ +G L+ L ++ + +N + + D + VP +
Sbjct: 1393 KKVRPLNNEGSLN-LLGLETIRLIYFKNKMAEGDELVVPETSDNSRKQMVRNINNKRRYS 1451
Query: 201 TIGKDDRSASERRSHIQ--------ISTPSDFMHIVHMGPAPVMEL 88
++ +RR ++ IS P++F HI HMGP +++
Sbjct: 1452 FRVPEEERMQQRREMLRDPEMRNKLISNPTNFNHIAHMGPGDGIQI 1497
>gi|30089960|ref|NP_055641.3| CDC42-binding protein kinase alpha
isoform A; ser-thr protein kinase related to the myotonic
dystrophy protein kinase; CDC42 binidng protein kinase
beta; ser-thr protein kinase PK428; myotonic dystrophy
kinase-related CDC42-binding protein kinase alpha;
CDC42-binding protein kinase alpha (DMPK-like) [Homo
sapiens]
Length = 1638
Score = 1049 bits (2712), Expect = 0.0
Identities = 632/1606 (39%), Positives = 925/1606 (57%), Gaps = 50/1606 (3%)
Frame = -1
Query: 4755 SAPVRLKTLENIYMDGPSK-KPEALSFETLIDSLICLYDECCNSTLRKEKCIAEFVESVK 4579
S VRL+ LE +DGP++ + S ETL+D LICLYDEC NS LR+EK I E++E K
Sbjct: 2 SGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWAK 61
Query: 4578 TVISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETAC 4399
SK K++RL R+DFE+LKVIG+GAFGEVAVV+++ +++AMKILNKWEM+KRAETAC
Sbjct: 62 PFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETAC 121
Query: 4398 FREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFY 4219
FREERDVLV GD +WIT LHYAFQD+ NLY VMDYY+GGD+LTLLSKF D +PE MA+FY
Sbjct: 122 FREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFY 181
Query: 4218 IAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASNVAVGTP 4039
+AEMV+AIDS+H+L YVHRD+KPDN+L+DM GHIRLADFGSCL+++ DG+V S+VAVGTP
Sbjct: 182 LAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTP 241
Query: 4038 DYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDML 3859
DYISPEIL+AMEDG+GRYG ECDWWSLG+CMYEMLYG TPFY+E LV+TYGKIM+H++
Sbjct: 242 DYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERF 301
Query: 3858 DFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIRDSNPPYV 3679
FP D VSE AKDLIR+LICS + R G+NG+ DF+ HPFF GIDW+ IR+ PY+
Sbjct: 302 QFPAQVTD--VSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYI 359
Query: 3678 PEVSSPEDTSNFDVDVCEDDFTPCLQ--ETQPPRVLAAFTGNHLPFVGFSYTHGSLLSDA 3505
PEVSSP DTSNFDVD DD CL+ ET PP AF+G+HLPFVGF+YT +LSD
Sbjct: 360 PEVSSPTDTSNFDVD---DD---CLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDR 413
Query: 3504 RSL-------TDEIRAIAQRCQGDAELMEKSVDGFMVELENEKAELVQKLKEA-QTIIA- 3352
L + ++ QR D L ++ + + LE EK EL +KL+E+ QT+ A
Sbjct: 414 SCLRVTAGPTSLDLDVNVQRTL-DNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQAL 472
Query: 3351 QHVAENPRSEEDRNYESTIAQLKDEIQILNKRLEDEALAQQQQKPKDEIVAXXXXXXXXX 3172
Q+ + ++ E I LK+EI+ L K++ + + +QQ +
Sbjct: 473 QYSTVDGPLTASKDLE--IKNLKEEIEKLRKQVTESSHLEQQLE---------------- 514
Query: 3171 XERNKQLVMEKSEIQRELDNINDHLDQVLVEKATVVQQRDDMQAELADVGDSLLTEKDSV 2992
E + +++ELD+ + + T+ Q+R+D+ +L ++L E
Sbjct: 515 ---------EANAVRQELDDAFRQIKAYEKQIKTLQQEREDLN-KLEVHTEALAAEASKD 564
Query: 2991 KRLQDEAEKAKKQVADFXXXXXXXXXXXXX---XXXKQEEVT-----IEARKSVETDDHL 2836
++L++++E KQ+ + Q+E+T +E +KS+ ++ L
Sbjct: 565 RKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEITKLKTDLE-KKSIFYEEEL 623
Query: 2835 SEEVVAAKNTIASLQATNEERE-------TEIKKLKQRMDEERASHTAQSEQEMKQLEAH 2677
S+ N I +L+ + E EI LK ++++ R ++ E+ + +
Sbjct: 624 SKREGIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQ 683
Query: 2676 YERAQKMLQDN--------------VEQMNVENRGLRDEIEKLSQQMAALPRGGLNEQQL 2539
YER + +L + E +++ N+ L +E++ L+ + ++ E Q+
Sbjct: 684 YEREKVLLTEENKKLTSELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHW---EAQI 740
Query: 2538 HEIFNWVSEEKATREEMENLTRKITGEVESLKNNSPLTTSNYIQNTPSGWGSRRMNNVAR 2359
EI WVS+EK R ++ L K+T E+E+L+N+S T + T W RR +
Sbjct: 741 TEIIQWVSDEKDARGYLQALASKMTEELEALRNSSLGTRA-----TDMPWKMRRFAKLDM 795
Query: 2358 KDGLDLQRQLQAEIDAKLKLKAELKNSQEQYLTSAARLDDTEKRMASLMREVAMLKQQKN 2179
L+LQ L AEI AK ++ EL + + + +L D+EK+ L+ E+ L +
Sbjct: 796 SARLELQSALDAEIRAKQAIQEELNKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTE 855
Query: 2178 IENSSDSAFSSTMGRGDLMISMNNDYEMSNSSLMRQEMISRQSTPSYENAILLHDHQVPK 1999
E S+ + + +N + +L + E + STP +
Sbjct: 856 -ELRSEKGIEHQDSQHSFLAFLNTPTD----ALDQFETVD--STP------------LSV 896
Query: 1998 RVDDLRYKQKPMKTASGIFSPVSISAMERGHNFERMKIKTPTKCGHCTSILIGLDRQGLF 1819
LR K P T F P + H F TPTKC CTS+++GL RQG
Sbjct: 897 HTPTLRKKGCPGSTG---FPP-----KRKTHQFFVKSFTTPTKCHQCTSLMVGLIRQGCS 948
Query: 1818 CQSCQYACHVSCAERVSQSCPVPEEERR-PLGIDPTRGVGTAYEGLVKTPRAGGVRKGWQ 1642
C+ C ++CH++C + +CPVP E+ + PLGIDP +G+GTAYEG V+ P+ GV+KGWQ
Sbjct: 949 CEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPKPAGVKKGWQ 1008
Query: 1641 TAYVVVCDFKLYLYDCTVDRQNKMQDVKNEIRLVLDMRDPDFTVCGVSEADVIHAQKGDI 1462
A +VCDFKL+LYD + ++ V I V+DMRD +F+V V +DVIHA + DI
Sbjct: 1009 RALAIVCDFKLFLYDIAEGKASQPSVV---ISQVIDMRDEEFSVSSVLASDVIHASRKDI 1065
Query: 1461 PKIFRVTTTQILNXXXXXXXXSKFYTLFMAETEEEKRKWVVALSELKTLLRRSKLADRKA 1282
P IFRVT +Q+ +K L +A+TE EK KWV LSEL +L+++K DR
Sbjct: 1066 PCIFRVTASQL------SASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSV 1119
Query: 1281 FLVKEVFDVTTLPSIRVAQCCAIIDRSKIVIGFSDHGLYCIEISRQLLIPVGGEKENKQR 1102
++ KE +D +TLP I+ Q AIID +I +G ++ GL+ + +++ +I VG K+
Sbjct: 1120 YVPKEAYD-STLPLIKTTQAAAIIDHERIALG-NEEGLFVVHVTKDEIIRVGDNKK---- 1173
Query: 1101 CVETVEYDEAEQLLMMIVGPAKDRHVRIVPSAALDGRDLKWIKVNDTKGCHLLAVGTNNP 922
+ +E +QL+ +I G ++RHVR+ P +ALDGR+ + K+++TKGC + G
Sbjct: 1174 -IHQIELIPNDQLVAVISG--RNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRH 1230
Query: 921 GGRAGFFAVAFKKSVTIFQIDRSEKRHKKWKDLAMPGTPQSIAIFNGRLYVGFSHSFRSW 742
G VA K+ V +++ +S+ RH+K+K++ +P Q +AIF+ +L VGF F +
Sbjct: 1231 GALT-CLCVAMKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRY 1289
Query: 741 SLVGVDSSPVGSGDASGAVLQHISLVNMEDTSLQFLNQQTSYEAKLIVNVPGSPDEYLLV 562
L G + +P S+++ D +L F+ Q I V S EYLL
Sbjct: 1290 PLNG-EGNPY-------------SMLHSNDHTLSFIAHQPM---DAICAVEISSKEYLLC 1332
Query: 561 FNMIGLYVNEMGRRSRLPEVMFPTQAKYFAYHEPYLCVFSENEVDIFNVTLAEWVQTINL 382
FN IG+Y + GRRSR E+M+P Y+ PYL V+SEN VDIF+V EW+QT+ L
Sbjct: 1333 FNSIGIYTDCQGRRSRQQELMWPANPSSCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPL 1392
Query: 381 RSAKPLSGDGILSTCLCNDSPIFVLLQNVLQDQDSIEVPVNLASGSTDGXXXXXXXXXXX 202
+ +PL+ +G L+ L ++ + +N + + D + VP +
Sbjct: 1393 KKVRPLNNEGSLN-LLGLETIRLIYFKNKMAEGDELVVPETSDNSRKQMVRNINNKRRYS 1451
Query: 201 TIGKDDRSASERRSHIQ--------ISTPSDFMHIVHMGPAPVMEL 88
++ +RR ++ IS P++F HI HMGP +++
Sbjct: 1452 FRVPEEERMQQRREMLRDPEMRNKLISNPTNFNHIAHMGPGDGIQI 1497
>gi|31240045|ref|XP_320436.1| ENSANGP00000009214 [Anopheles gambiae]
gi|30174083|gb|EAA00280.2| ENSANGP00000009214 [Anopheles gambiae str.
PEST]
Length = 1573
Score = 1043 bits (2697), Expect = 0.0
Identities = 631/1623 (38%), Positives = 926/1623 (56%), Gaps = 83/1623 (5%)
Frame = -1
Query: 4686 LSFETLIDSLICLYDECCNSTLRKEKCIAEFVESVKTVISKAKKLRLSRDDFEVLKVIGK 4507
LS ET++D L+ LYDECCNS+LR+EK +++F+E +K+V+ K+LRLSRDDFEVLKVIG+
Sbjct: 4 LSVETMLDCLVVLYDECCNSSLRREKTVSDFIELMKSVVQSVKQLRLSRDDFEVLKVIGR 63
Query: 4506 GAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACFREERDVLVYGDRRWITNLHYAFQ 4327
GAFGEV VVRM +IYAMKILNKWEM+KRAETACFREERDVLV+GDRRWITNLHYAFQ
Sbjct: 64 GAFGEVCVVRMHHTSQIYAMKILNKWEMLKRAETACFREERDVLVFGDRRWITNLHYAFQ 123
Query: 4326 DEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFYIAEMVLAIDSLHRLGYVHRDVKPD 4147
D+ NLY +MDYY GGD+LTLLSKF D +PE MA+FYIAEMVLAI S+H L YVHRD+KPD
Sbjct: 124 DDINLYLIMDYYCGGDLLTLLSKFEDRLPEDMARFYIAEMVLAIHSIHELKYVHRDIKPD 183
Query: 4146 NVLLDMQGHIRLADFGSCLRILADGSVASNVAVGTPDYISPEILRAMEDGRGRYGKECDW 3967
N++LD GH+RLADFGSCLR+ G+V SNVAVGTPDYISPEILRAMEDG+G+YG ECDW
Sbjct: 184 NIVLDASGHVRLADFGSCLRLGPQGTVQSNVAVGTPDYISPEILRAMEDGQGKYGPECDW 243
Query: 3966 WSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDMLDFPDDEIDWVVSEEAKDLIRQLIC 3787
WSLG+CMYEML+G TPFY+E LV+TYGKIM+H++ DFP+D+ ++ VSE+AKDLIR+LIC
Sbjct: 244 WSLGVCMYEMLFGETPFYAESLVETYGKIMNHKNSFDFPNDDDEFGVSEQAKDLIRRLIC 303
Query: 3786 SSDVRFGRNGLSDFQLHPFFEGIDWNTIRDSNPPYVPEVSSPEDTSNFDVDVCEDDFTPC 3607
+ + R G+NG+ DF+ HP+FEGI W+TIR+ PY+PEVSSP DTSNFDV DD
Sbjct: 304 APEYRLGQNGIDDFKAHPWFEGISWDTIRNGQAPYIPEVSSPTDTSNFDV----DDTDIK 359
Query: 3606 LQETQPPRVLAAFTGNHLPFVGFSYTHGSLLSDARSLTDEIRAIAQRCQ----------G 3457
L + PP AF+G+HLPFVGF++T S LSD L+ I + Q G
Sbjct: 360 LSDAVPPTTNPAFSGHHLPFVGFTFTKDSSLSDVGRLSRAITSTNSASQPLPPLKLEKHG 419
Query: 3456 DAELMEKSVDGFMVELENE-------KAELVQKLKEAQTIIAQHVAENPRSEE-DRNYES 3301
E S D +L++E EL ++K + + A V + D ++
Sbjct: 420 SEEKQRLSPDSTR-KLQDEINILTKRNCELESQIKSFERVGAMSVGTAAAGDSVDGQVDA 478
Query: 3300 TIAQLKDEIQILNKRLED---------EALAQQQQKPKDEIVAXXXXXXXXXXERNK--Q 3154
I + + I++L + ED + L QQ ++ KD + +K
Sbjct: 479 KIKENEKMIRLLRQEKEDLAKEHQDALDRLKQQDKELKDALEQRKLAMAEYTEVTDKLSD 538
Query: 3153 LVMEKSEIQRELDNINDHLDQVLVEKATV---VQQRDDMQAELADVGDSLLTEKDSVKRL 2983
L +K ++ R++ + + L+ + + T+ +++ D ++ E L++E + ++
Sbjct: 539 LRQQKQKLSRQVRDKEEELEVTMQKVDTLRSELRKTDKLRREQDARIQDLISELNRERQQ 598
Query: 2982 QDEAEKAKKQVADFXXXXXXXXXXXXXXXXKQEEVTIEA---RKSVETDDHLSE------ 2830
++ +E+ +Q+ +I R VE + +++
Sbjct: 599 RERSEECYRQLQMEARSRSSSELGSSNSLGISSSDSIRLEIDRLEVEYSEKINQQQTRYN 658
Query: 2829 -EVVAAKNTIASLQATNEERETEIKKLKQRMDEERASHTAQSEQEMKQLEAHYERAQKML 2653
E+ A ++ + E + E+++ ++++D R SE+ + +L +ER +K+L
Sbjct: 659 IEISALRDQLNEADNHREMLQRELQQAREKLDSSRLESLTDSEETILELRKRHEREKKIL 718
Query: 2652 QD-------NVEQMNVENRGL-------RDEIEKLSQQMAALPRGGLNEQQLHEIFNWVS 2515
D ++E ++ NR L E E L + A + E+Q+ EI WVS
Sbjct: 719 LDDNRKLITDLEMISESNRRLTAERLQMESEYEDLRNRRQAFSQW---ERQIAEIIQWVS 775
Query: 2514 EEKATREEMENLTRKITGEVESLKNNSPLTTSNYIQNTPSGWGSRRMNNVARKDGLDLQR 2335
+EK R ++ L K+T E+E LK+ PL N+ + W +RR + + + L+LQ
Sbjct: 776 DEKDARGYLQALATKMTEELEYLKHTGPL---NHNASDNKNWRNRRSQKLDKMELLNLQS 832
Query: 2334 QLQAEIDAKLKLKAELKNSQEQYLTSAARLDDT----EKRMASLMREVAMLKQ-QKNIEN 2170
LQ EI AK + EL ++ + + L +T E + L R+ +++K+ Q+ +E+
Sbjct: 833 SLQNEIQAKAVISEELTRTRTDLVAAQKDLRETRQICESIGSELKRKESVIKELQQRLES 892
Query: 2169 SSDSAFSSTMGRGDLMISMNNDYEMSNSSLMRQEMISRQSTP-SYENAILLHDHQVPKRV 1993
+ + S DL+ ++ ++ + R E S + +P S N + P V
Sbjct: 893 NEGWSSPSVEQVNDLVAALLTP-PVTPQLVARDEQESEEESPYSIANTDSANVENTPTGV 951
Query: 1992 -----DDLRYKQKPMKTASGIFSPVSI----SAMERGHNFERMKIKTPTKCGHCTSILIG 1840
D + +A I SP + + H F +PTKC HCTS+++G
Sbjct: 952 ATEEEHDESSMPLLLDSAEQIPSPADLHPHRQQKAKVHQFLVRTFSSPTKCNHCTSLMVG 1011
Query: 1839 LDRQGLFCQSCQYACHVSCAERVSQSCPVPEEE-RRPLGIDPTRGVGTAYEGLVKTPRAG 1663
L RQG+ C+ C +ACH+ C +V CPVP ++ +RPLGIDPTRG+GTAYEG VK P+ G
Sbjct: 1012 LTRQGVVCELCGFACHMICCPKVPTQCPVPSDQTKRPLGIDPTRGIGTAYEGYVKVPKLG 1071
Query: 1662 GVRKGWQTAYVVVCDFKLYLYDCTVDRQNKMQDVKNEIRLVLDMRDPDFTVCGVSEADVI 1483
GV++GW +VVVCDFKL+LYD + DR + + V + VLDMRDP+FTV GV E+DVI
Sbjct: 1072 GVKRGWVRQFVVVCDFKLFLYDISADR-SALPSV--HVTQVLDMRDPEFTVSGVRESDVI 1128
Query: 1482 HAQKGDIPKIFRVTTTQILNXXXXXXXXSKFYTLFMAETEEEKRKWVVALSELKTLLRRS 1303
HA K D+P IFR+TT+ + TL +A+TE EK KWVVALSEL +L+R+
Sbjct: 1129 HATKKDVPCIFRITTSLL-------DGGPSLQTLMLADTESEKAKWVVALSELHRILKRN 1181
Query: 1302 KLADRKAFLVKEVFDVTTLPSIRVAQCCAIIDRSKIVIGFSDHGLYCIEISRQLLIPVGG 1123
L + F V+EV D +T+ +IR A IID +I++G D GL+C+++ R + +G
Sbjct: 1182 NLPNTAMFRVREVLD-STVSAIRNALSALIIDPERILLGTED-GLFCLDLDRSQIARIGE 1239
Query: 1122 EKENKQRCVETVEYDEAEQLLMMIVGPAKDRHVRIVPSAALDGRDLKWIKVNDTKGCHLL 943
K+ V + Y EQLL+++ G K RH+R++P AL+ D++WIKV ++K C
Sbjct: 1240 SKK-----VYQLWYIAEEQLLVILCG--KQRHLRLLPIRALETVDVEWIKVAESKNCITA 1292
Query: 942 AVGTNNPGGRAGFFAVAFKK-----SVTIFQIDRSEKRHKKWKDLAMPGTPQSIAIFNG- 781
G G + F V K + ++ ++R RH K + + QS+ + +
Sbjct: 1293 CTGIIERGPQPVFCIVLALKRQNTSQIVVYVVNRDRSRHHKMCEFTVAYPVQSLQVLSDM 1352
Query: 780 RLYVGFSHSFRSWSLVGVDSSPVGSGDASGAVLQHISLVNMEDTSLQFLNQQTSYEAKLI 601
RL VG F ++ L G + + LV+ E+ FLN + +A +
Sbjct: 1353 RLAVGHQSGFTAYCLQGAAKA--------------MPLVHPENQLNNFLN-FSGVDAWRV 1397
Query: 600 VNVPGS-----PDEYLLVFNMIGLYVNEMGRRSRLPEVMFPTQAKYFAYHEPYLCVFSEN 436
+ + EYLLVF + +YV+ GR+SR E+M+P K+ Y + +L V+SE
Sbjct: 1398 IEIQSGHGGNVHGEYLLVFQTLAIYVDLQGRKSRDREIMYPAVPKHITYCDGHLLVYSET 1457
Query: 435 EVDIFNVTLAEWVQTINLRSAKPLSGDGILSTCLCNDSPIFVLLQNVLQDQDSIEVPVNL 256
+DIFN AEWVQ+I L+ ++PL +G L+ ND V L N+ +NL
Sbjct: 1458 HLDIFNTQTAEWVQSIGLKRSRPLMNNGSLTLTYINDGVNVVYLANM-----HTRELLNL 1512
Query: 255 ASGSTDGXXXXXXXXXXXTIGKDDRSASERRSHIQISTPSDFMHIVHMGPAPVMELQQNF 76
+ DG + R++++RRS + IS P++F HI HMGP ++ +Q
Sbjct: 1513 SPCDRDGRLKSKRFSLREP-NRTIRTSTDRRSKL-ISAPTNFNHISHMGPGDGIQ-KQRL 1569
Query: 75 IDL 67
+DL
Sbjct: 1570 LDL 1572
>gi|16758474|ref|NP_446109.1| CDC42-binding protein kinase alpha;
mytonic dystrophy kinase-related Cdc42-binding kinase
[Rattus norvegicus]
gi|7446379|pir||T14039 protein kinase (EC 2.7.1.37), myotonic
dystrophy-associated - rat
gi|2736151|gb|AAC02941.1| mytonic dystrophy kinase-related
Cdc42-binding kinase [Rattus norvegicus]
Length = 1732
Score = 1041 bits (2691), Expect = 0.0
Identities = 632/1665 (37%), Positives = 928/1665 (54%), Gaps = 109/1665 (6%)
Frame = -1
Query: 4755 SAPVRLKTLENIYMDGPSK-KPEALSFETLIDSLICLYDECCNSTLRKEKCIAEFVESVK 4579
S VRL+ LE +DGP++ + S ETL+D LICLYDEC NS LR+EK I E++E K
Sbjct: 2 SGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWAK 61
Query: 4578 TVISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETAC 4399
SK K++RL R+DFE+LKVIG+GAFGEVAVV+++ +++AMKILNKWEM+KRAETAC
Sbjct: 62 PFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETAC 121
Query: 4398 FREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFY 4219
FREERDVLV GD +WIT LHYAFQD+ NLY VMDYY+GGD+LTLLSKF D +PE MA+FY
Sbjct: 122 FREERDVLVNGDSKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEEMARFY 181
Query: 4218 IAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASNVAVGTP 4039
+AEMV+AIDS+H+L YVHRD+KPDN+L+DM GHIRLADFGSCL+++ DG+V S+VAVGTP
Sbjct: 182 LAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTP 241
Query: 4038 DYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDML 3859
DYISPEIL+AMEDG+GRYG ECDWWSLG+CMYEMLYG TPFY+E LV+TYGKIM+H++
Sbjct: 242 DYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERF 301
Query: 3858 DFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIRDSNPPYV 3679
FP D VSE AKDLIR+LICS + R G+NG+ DF+ HPFF GIDW+ IR+ PY+
Sbjct: 302 QFPTQVTD--VSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYI 359
Query: 3678 PEVSSPEDTSNFDVDVCEDDFTPCLQ--ETQPPRVLAAFTGNHLPFVGFSYTHGSLLSDA 3505
PEVSSP DTSNFDVD DD CL+ ET PP AF+G+HLPFVGF+YT +LSD
Sbjct: 360 PEVSSPTDTSNFDVD---DD---CLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDR 413
Query: 3504 RSL-------TDEIRAIAQRCQGDAELMEKSVDGFMVELENEKAELVQKLKEA-QTIIA- 3352
L + ++ QR D L ++ + + LE EK EL +KL+E+ QT+ A
Sbjct: 414 SCLRVTAGPTSLDLDVNVQRTL-DNNLATEAYERRIKRLEQEKLELTRKLQESTQTVQAL 472
Query: 3351 QHVAENPRSEEDRNYESTIAQLKDEIQILNKRLEDEALAQQQQKPKDEIVAXXXXXXXXX 3172
Q+ + ++ E I LK+EI+ L K++ + +QQ + + +
Sbjct: 473 QYSTVDGPLTASKDLE--IKSLKEEIEKLRKQVAEVNHLEQQLEEANSVRRELDDAFRQI 530
Query: 3171 XERNKQ---LVMEKSEIQREL----------------------------DNINDHLDQVL 3085
KQ L E+ E+ +EL IN+ L ++
Sbjct: 531 KAFEKQIKTLQQEREELNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELH 590
Query: 3084 VEKATVVQQRDDMQAELADVGDSLLTEKDSVKRLQDEAEKAKKQVADFXXXXXXXXXXXX 2905
+K + + D + E+ D ++ + +S+++ AE+AKK++
Sbjct: 591 TQKQKLARHVRDKEEEV----DLVMQKAESLRQELRRAERAKKELEVHTEALIAEASKDR 646
Query: 2904 X-------------------------------XXXKQEEVTIEARKSVETDDHLSEEVVA 2818
Q+E+T + + +E EE ++
Sbjct: 647 KLREQSRHYSKQLENELEGLKQKQISYSPGICSIEHQQEIT-KLKTDLEKKSIFYEEEIS 705
Query: 2817 AKNTIASLQATNEERE------------TEIKKLKQRMDEERASHTAQSEQEMKQLEAHY 2674
+ I + + N ++E EI LK ++++ R ++ E+ + + Y
Sbjct: 706 KREGIHASEIKNLKKELHDSEGQQLALNKEIMVLKDKLEKTRRESQSEREEFENEFKQQY 765
Query: 2673 ERAQKMLQDN--------------VEQMNVENRGLRDEIEKLSQQMAALPRGGLNEQQLH 2536
ER + +L + E +++ N+ L +E++ L+ + ++ E Q+
Sbjct: 766 EREKVLLTEENKKLTSELDKLTSLYESLSLRNQHLEEEVKDLADKKESVAHW---EAQIT 822
Query: 2535 EIFNWVSEEKATREEMENLTRKITGEVESLKNNSPLTTSNYIQNTPSGWGSRRMNNVARK 2356
EI WVS+EK R ++ L K+T E+E+L+N+S T + T W RR +
Sbjct: 823 EIIQWVSDEKDARGYLQALASKMTEELEALRNSSLGTRA-----TDMPWKMRRFAKLDMS 877
Query: 2355 DGLDLQRQLQAEIDAKLKLKAELKNSQEQYLTSAARLDDTEKRMASLMREVAMLKQQKNI 2176
L+LQ L AEI AK ++ EL + + + +L D+EK+ L+ E+ L +
Sbjct: 878 ARLELQSALDAEIRAKQAIQEELNKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTE- 936
Query: 2175 ENSSDSAFSSTMGRGDLMISMNNDYEMSNSSLMRQEMISRQSTPSYENAILLHDHQVPKR 1996
E S+ + + +N + + + Q S TP+ + + +P
Sbjct: 937 ELRSEKGVEHRDSQHSFLAFLN-----TPTDALDQFERSPSCTPAGKGRRIADSAPLPVH 991
Query: 1995 VDDLRYKQKPMKTASGIFSPVSISAMERGHNFERMKIKTPTKCGHCTSILIGLDRQGLFC 1816
LR K P AS F P + H F PTKC CTS+++GL RQG C
Sbjct: 992 TPTLRKKGCP---ASAGFPP-----KRKTHQFFVKSFTAPTKCHQCTSLMVGLIRQGCSC 1043
Query: 1815 QSCQYACHVSCAERVSQSCPVPEEERR-PLGIDPTRGVGTAYEGLVKTPRAGGVRKGWQT 1639
+ C ++CH++C + +CPVP E+ + PLGIDP +GVGTAYEG V+ P+ GV+KGWQ
Sbjct: 1044 EVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGVGTAYEGHVRIPKPAGVKKGWQR 1103
Query: 1638 AYVVVCDFKLYLYDCTVDRQNKMQDVKNEIRLVLDMRDPDFTVCGVSEADVIHAQKGDIP 1459
A VVCDFKL+LYD + K + I V+DMRD +F+V V +DVIHA + DIP
Sbjct: 1104 ALAVVCDFKLFLYDIA---EGKASQPSSVISQVIDMRDEEFSVSSVLASDVIHASRKDIP 1160
Query: 1458 KIFRVTTTQILNXXXXXXXXSKFYTLFMAETEEEKRKWVVALSELKTLLRRSKLADRKAF 1279
IFRVT +Q+ K L +A++E E+ KWV LSEL +L+++K DR +
Sbjct: 1161 CIFRVTASQL------SAPSDKCSILMLADSETERSKWVGVLSELHKVLKKNKFRDRSVY 1214
Query: 1278 LVKEVFDVTTLPSIRVAQCCAIIDRSKIVIGFSDHGLYCIEISRQLLIPVGGEKENKQRC 1099
+ KE +D +TLP I+ Q AIID ++ +G ++ GL+ + +++ +I VG K+
Sbjct: 1215 VPKEAYD-STLPLIKTTQAAAIIDHERVALG-NEEGLFVVHVTKDEIIRVGDNKK----- 1267
Query: 1098 VETVEYDEAEQLLMMIVGPAKDRHVRIVPSAALDGRDLKWIKVNDTKGCHLLAVGTNNPG 919
+ +E ++QL+ +I G ++RHVR+ P +ALDGR+ + K+ +TKGC +A G G
Sbjct: 1268 IHQIELIPSDQLVAVISG--RNRHVRLFPMSALDGRETDFYKLAETKGCQTIAAGKVRHG 1325
Query: 918 GRAGFFAVAFKKSVTIFQIDRSEKRHKKWKDLAMPGTPQSIAIFNGRLYVGFSHSFRSWS 739
VA K+ V +++ +S+ RH+K+K++ +P Q +AIF+ L VGF F +
Sbjct: 1326 A-LSCLCVAMKRQVLCYELFQSKTRHRKFKEIQVPCNVQWMAIFSEHLCVGFQSGFLRYP 1384
Query: 738 LVGVDSSPVGSGDASGAVLQHISLVNMEDTSLQFLNQQTSYEAKLIVNVPGSPDEYLLVF 559
L G + SP ++++ D +L F+ Q I V S EYLL F
Sbjct: 1385 LNG-EGSP-------------CNMLHSNDHTLAFITHQ---PMDAICAVEISNKEYLLCF 1427
Query: 558 NMIGLYVNEMGRRSRLPEVMFPTQAKYFAYHEPYLCVFSENEVDIFNVTLAEWVQTINLR 379
+ IG+Y + GRRSR E+M+P Y+ PYL ++SEN VDIF+V EW+QT+ L+
Sbjct: 1428 SSIGIYTDCQGRRSRQQELMWPANPSSCCYNAPYLSIYSENAVDIFDVNSMEWIQTLPLK 1487
Query: 378 SAKPLSGDGILSTCLCNDSPIFVLLQNVLQDQDSIEVPVNLASGSTDGXXXXXXXXXXXT 199
+PL+ +G L+ L ++ + +N + + D + VP +
Sbjct: 1488 KVRPLNTEGSLN-LLGLETIRLIYFKNKMAEGDELVVPETSDNSRKQMVRNINNKRRYSF 1546
Query: 198 IGKDDRSASERRSHIQ--------ISTPSDFMHIVHMGPAPVMEL 88
++ +RR ++ IS P++F HI HMGP +++
Sbjct: 1547 RVPEEERMQQRREMLRDPEMRNKLISNPTNFNHIAHMGPGDGIQI 1591
>gi|27261723|gb|AAN86031.1| CDC42-binding protein kinase beta [Homo
sapiens]
Length = 1638
Score = 1040 bits (2689), Expect = 0.0
Identities = 628/1606 (39%), Positives = 922/1606 (57%), Gaps = 50/1606 (3%)
Frame = -1
Query: 4755 SAPVRLKTLENIYMDGPSK-KPEALSFETLIDSLICLYDECCNSTLRKEKCIAEFVESVK 4579
S VRL+ LE +DGP++ + S ETL+D LICLYDEC NS LR+EK I E++E K
Sbjct: 2 SGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWAK 61
Query: 4578 TVISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETAC 4399
SK K++RL R+DFE+LKVIG+GAFGEVAVV+++ +++AMKILNKWEM+KRAETAC
Sbjct: 62 PFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETAC 121
Query: 4398 FREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFY 4219
FREERDVLV GD +WIT LHYAFQD+ NLY VMDYY+GGD+LTLLSKF D +PE MA+FY
Sbjct: 122 FREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFY 181
Query: 4218 IAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASNVAVGTP 4039
+AEMV+AIDS+H+L YVHRD+KPDN+L+DM GHIRLADFGSCL+++ DG+V S+VAVGTP
Sbjct: 182 LAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTP 241
Query: 4038 DYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDML 3859
DYISPEIL+AMEDG+GRYG ECDWWSLG+CMYEMLYG TPFY+E LV+TYGKIM+H++
Sbjct: 242 DYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERF 301
Query: 3858 DFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIRDSNPPYV 3679
FP D VSE AKD IR+LIC + R G++G+ DF+ HPFF GIDW+ IR+ PY+
Sbjct: 302 QFPAQVTD--VSENAKDPIRRLICGREHRLGQSGIEDFKKHPFFSGIDWDNIRNCEAPYI 359
Query: 3678 PEVSSPEDTSNFDVDVCEDDFTPCLQ--ETQPPRVLAAFTGNHLPFVGFSYTHGSLLSDA 3505
PEVSSP DTSNFDVD DD CL+ ET PP AF+G+HLPFVGF+YT +LSD
Sbjct: 360 PEVSSPTDTSNFDVD---DD---CLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDR 413
Query: 3504 RSL-------TDEIRAIAQRCQGDAELMEKSVDGFMVELENEKAELVQKLKEA-QTIIA- 3352
L + ++ QR D L ++ + + LE EK EL +KL+E+ QT+ A
Sbjct: 414 SCLRVTAGPTSLDLDVNVQRTL-DNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQAL 472
Query: 3351 QHVAENPRSEEDRNYESTIAQLKDEIQILNKRLEDEALAQQQQKPKDEIVAXXXXXXXXX 3172
Q+ + ++ E I LK+ I+ L K++ + + +QQ +
Sbjct: 473 QYSTVDGPLTASKDLE--IKNLKEVIEKLRKQVTESSHLEQQLE---------------- 514
Query: 3171 XERNKQLVMEKSEIQRELDNINDHLDQVLVEKATVVQQRDDMQAELADVGDSLLTEKDSV 2992
E + +++ELD+ + + T+ Q+R+D+ +L ++L E
Sbjct: 515 ---------EANAVRQELDDAFRQIKAYEKQIKTLQQEREDLN-KLEVHTEALAAEASKD 564
Query: 2991 KRLQDEAEKAKKQVADFXXXXXXXXXXXXX---XXXKQEEVT-----IEARKSVETDDHL 2836
++L++++E KQ+ + Q+E+T +E +KS+ ++ L
Sbjct: 565 RKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEITKLKTDLE-KKSIFYEEEL 623
Query: 2835 SEEVVAAKNTIASLQATNEERE-------TEIKKLKQRMDEERASHTAQSEQEMKQLEAH 2677
S+ N I +L+ + E EI LK ++++ R ++ E+ + +
Sbjct: 624 SKREGIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQ 683
Query: 2676 YERAQKMLQDN--------------VEQMNVENRGLRDEIEKLSQQMAALPRGGLNEQQL 2539
YER + +L + E +++ N+ L +E++ L+ + ++ E Q+
Sbjct: 684 YEREKVLLTEENKKLTSELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHW---EAQI 740
Query: 2538 HEIFNWVSEEKATREEMENLTRKITGEVESLKNNSPLTTSNYIQNTPSGWGSRRMNNVAR 2359
EI WVS+EK R ++ L K+T E+E+L+N+S T + T W RR +
Sbjct: 741 TEIIQWVSDEKDARGYLQALASKMTEELEALRNSSLGTRA-----TDMPWKMRRFAKLDM 795
Query: 2358 KDGLDLQRQLQAEIDAKLKLKAELKNSQEQYLTSAARLDDTEKRMASLMREVAMLKQQKN 2179
L+LQ L AEI AK ++ EL + + + +L D+EK+ L+ E+ L +
Sbjct: 796 SARLELQSALDAEIRAKQAIQEELNKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTE 855
Query: 2178 IENSSDSAFSSTMGRGDLMISMNNDYEMSNSSLMRQEMISRQSTPSYENAILLHDHQVPK 1999
E S+ + + +N + +L + E + STP +
Sbjct: 856 -ELRSEKGIEHQDSQHSFLAFLNTPTD----ALDQFETVD--STP------------LSV 896
Query: 1998 RVDDLRYKQKPMKTASGIFSPVSISAMERGHNFERMKIKTPTKCGHCTSILIGLDRQGLF 1819
LR K P T F P + H F TPTKC CTS+++GL RQG
Sbjct: 897 HTPTLRKKGCPGSTG---FPP-----KRKTHQFFVKSFTTPTKCHQCTSLMVGLIRQGCS 948
Query: 1818 CQSCQYACHVSCAERVSQSCPVPEEERR-PLGIDPTRGVGTAYEGLVKTPRAGGVRKGWQ 1642
C+ C ++CH++C + +CPVP E+ + PLGIDP +G+GTAYEG V+ P+ GV+KGWQ
Sbjct: 949 CEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPKPAGVKKGWQ 1008
Query: 1641 TAYVVVCDFKLYLYDCTVDRQNKMQDVKNEIRLVLDMRDPDFTVCGVSEADVIHAQKGDI 1462
A +VCDFKL+LYD + ++ V I V+DMRD +F+V V +DVIHA + DI
Sbjct: 1009 RALAIVCDFKLFLYDIAEGKASQPSVV---ISQVIDMRDEEFSVSSVLASDVIHASRKDI 1065
Query: 1461 PKIFRVTTTQILNXXXXXXXXSKFYTLFMAETEEEKRKWVVALSELKTLLRRSKLADRKA 1282
P IFRVT +Q+ +K L +A+TE EK KWV LSEL +L+++K DR
Sbjct: 1066 PCIFRVTASQL------SASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSV 1119
Query: 1281 FLVKEVFDVTTLPSIRVAQCCAIIDRSKIVIGFSDHGLYCIEISRQLLIPVGGEKENKQR 1102
++ KE +D +TLP I+ Q AIID +I +G ++ GL+ + +++ +I VG K+
Sbjct: 1120 YVPKEAYD-STLPLIKTTQAAAIIDHERIALG-NEEGLFVVHVTKDEIIRVGDNKK---- 1173
Query: 1101 CVETVEYDEAEQLLMMIVGPAKDRHVRIVPSAALDGRDLKWIKVNDTKGCHLLAVGTNNP 922
+ +E +QL+ +I G ++RHVR+ P +ALDGR+ + K+++TKGC + G
Sbjct: 1174 -IHQIELIPNDQLVAVISG--RNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRH 1230
Query: 921 GGRAGFFAVAFKKSVTIFQIDRSEKRHKKWKDLAMPGTPQSIAIFNGRLYVGFSHSFRSW 742
G VA K+ V +++ +S+ RH+K+K++ +P Q +AIF+ +L VGF F +
Sbjct: 1231 GALT-CLCVAMKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRY 1289
Query: 741 SLVGVDSSPVGSGDASGAVLQHISLVNMEDTSLQFLNQQTSYEAKLIVNVPGSPDEYLLV 562
L G + +P S+++ D +L F+ Q I V S EYLL
Sbjct: 1290 PLNG-EGNPY-------------SMLHSNDHTLSFIAHQPM---DAICAVEISSKEYLLC 1332
Query: 561 FNMIGLYVNEMGRRSRLPEVMFPTQAKYFAYHEPYLCVFSENEVDIFNVTLAEWVQTINL 382
FN IG+Y + GRRSR E+M+P Y+ PYL V+SEN VDIF+V EW+QT+ L
Sbjct: 1333 FNSIGIYTDCQGRRSRQQELMWPANPSSCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPL 1392
Query: 381 RSAKPLSGDGILSTCLCNDSPIFVLLQNVLQDQDSIEVPVNLASGSTDGXXXXXXXXXXX 202
+ +PL+ +G L+ L ++ + +N + + D + VP +
Sbjct: 1393 KKVRPLNNEGSLN-LLGLETIRLIYFKNKMAEGDELVVPETSDNSRKQMVRNINNKRRYS 1451
Query: 201 TIGKDDRSASERRSHIQ--------ISTPSDFMHIVHMGPAPVMEL 88
++ +RR ++ IS P++F HI HMGP +++
Sbjct: 1452 FRVPEEERMQQRREMLRDPEMRNKLISNPTNFNHIAHMGPGDGIQI 1497
>gi|30089962|ref|NP_003598.2| CDC42-binding protein kinase alpha
isoform B; ser-thr protein kinase related to the myotonic
dystrophy protein kinase; CDC42 binidng protein kinase
beta; ser-thr protein kinase PK428; myotonic dystrophy
kinase-related CDC42-binding protein kinase alpha;
CDC42-binding protein kinase alpha (DMPK-like) [Homo
sapiens]
Length = 1719
Score = 1036 bits (2680), Expect = 0.0
Identities = 633/1659 (38%), Positives = 925/1659 (55%), Gaps = 103/1659 (6%)
Frame = -1
Query: 4755 SAPVRLKTLENIYMDGPSK-KPEALSFETLIDSLICLYDECCNSTLRKEKCIAEFVESVK 4579
S VRL+ LE +DGP++ + S ETL+D LICLYDEC NS LR+EK I E++E K
Sbjct: 2 SGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWAK 61
Query: 4578 TVISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETAC 4399
SK K++RL R+DFE+LKVIG+GAFGEVAVV+++ +++AMKILNKWEM+KRAETAC
Sbjct: 62 PFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETAC 121
Query: 4398 FREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFY 4219
FREERDVLV GD +WIT LHYAFQD+ NLY VMDYY+GGD+LTLLSKF D +PE MA+FY
Sbjct: 122 FREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFY 181
Query: 4218 IAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASNVAVGTP 4039
+AEMV+AIDS+H+L YVHRD+KPDN+L+DM GHIRLADFGSCL+++ DG+V S+VAVGTP
Sbjct: 182 LAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTP 241
Query: 4038 DYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDML 3859
DYISPEIL+AMEDG+GRYG ECDWWSLG+CMYEMLYG TPFY+E LV+TYGKIM+H++
Sbjct: 242 DYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERF 301
Query: 3858 DFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIRDSNPPYV 3679
FP D VSE AKDLIR+LICS + R G+NG+ DF+ HPFF GIDW+ IR+ PY+
Sbjct: 302 QFPAQVTD--VSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYI 359
Query: 3678 PEVSSPEDTSNFDVDVCEDDFTPCLQ--ETQPPRVLAAFTGNHLPFVGFSYTHGSLLSDA 3505
PEVSSP DTSNFDVD DD CL+ ET PP AF+G+HLPFVGF+YT +LSD
Sbjct: 360 PEVSSPTDTSNFDVD---DD---CLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDR 413
Query: 3504 RSL-------TDEIRAIAQRCQGDAELMEKSVDGFMVELENEKAELVQKLKEA-QTI--- 3358
L + ++ QR D L ++ + + LE EK EL +KL+E+ QT+
Sbjct: 414 SCLRVTAGPTSLDLDVNVQRTL-DNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQAL 472
Query: 3357 --------------------------IAQHVAENPRSEED------------------RN 3310
+ + V E+ E+ +
Sbjct: 473 QYSTVDGPLTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKA 532
Query: 3309 YESTIAQLKDEIQILNKRL--EDEALAQQQQKPKDEIVAXXXXXXXXXXERNK--QLVME 3142
YE I L+ E + LNK L E L Q ++ KD + +L +
Sbjct: 533 YEKQIKTLQQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQ 592
Query: 3141 KSEIQRELDNINDHLDQVLVEKATVVQQ---RDDMQAELADVGDSLLTEKDSVKRLQDEA 2971
K ++ R + + + +D V+ + ++ Q+ + + EL ++L E ++L++++
Sbjct: 593 KQKLARHVRDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQS 652
Query: 2970 EKAKKQV---ADFXXXXXXXXXXXXXXXXKQEEVTIEARKSVETDDHLSEEVVAAKNTIA 2800
E KQ+ + Q+E+T + + +E EE ++ + I
Sbjct: 653 EHYSKQLENELEGLKQKQISYSPGVCSIEHQQEIT-KLKTDLEKKSIFYEEELSKREGIH 711
Query: 2799 SLQATNEERE------------TEIKKLKQRMDEERASHTAQSEQEMKQLEAHYERAQKM 2656
+ + N ++E EI LK ++++ R ++ E+ + + YER + +
Sbjct: 712 ANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVL 771
Query: 2655 LQDN--------------VEQMNVENRGLRDEIEKLSQQMAALPRGGLNEQQLHEIFNWV 2518
L + E +++ N+ L +E++ L+ + ++ E Q+ EI WV
Sbjct: 772 LTEENKKLTSELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHW---EAQITEIIQWV 828
Query: 2517 SEEKATREEMENLTRKITGEVESLKNNSPLTTSNYIQNTPSGWGSRRMNNVARKDGLDLQ 2338
S+EK R ++ L K+T E+E+L+N+S T + T W RR + L+LQ
Sbjct: 829 SDEKDARGYLQALASKMTEELEALRNSSLGTRA-----TDMPWKMRRFAKLDMSARLELQ 883
Query: 2337 RQLQAEIDAKLKLKAELKNSQEQYLTSAARLDDTEKRMASLMREVAMLKQQKNIENSSDS 2158
L AEI AK ++ EL + + + +L D+EK+ L+ E+ L I+++ +
Sbjct: 884 SALDAEIRAKQAIQEELNKVKASNIITECKLKDSEKKNLELLSEIEQL-----IKDTEEL 938
Query: 2157 AFSSTMGRGDLMISMNNDYEMSNSSLMRQEMISRQSTPSYENAILLHDHQVPKRVDDLRY 1978
+ D S +L + E + STP + LR
Sbjct: 939 RSEKGIEHQDSQHSFLAFLNTPTDALDQFETV--DSTP------------LSVHTPTLRK 984
Query: 1977 KQKPMKTASGIFSPVSISAMERGHNFERMKIKTPTKCGHCTSILIGLDRQGLFCQSCQYA 1798
K P T F P + H F TPTKC CTS+++GL RQG C+ C ++
Sbjct: 985 KGCPGSTG---FPP-----KRKTHQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFS 1036
Query: 1797 CHVSCAERVSQSCPVPEEERR-PLGIDPTRGVGTAYEGLVKTPRAGGVRKGWQTAYVVVC 1621
CH++C + +CPVP E+ + PLGIDP +G+GTAYEG V+ P+ GV+KGWQ A +VC
Sbjct: 1037 CHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPKPAGVKKGWQRALAIVC 1096
Query: 1620 DFKLYLYDCTVDRQNKMQDVKNEIRLVLDMRDPDFTVCGVSEADVIHAQKGDIPKIFRVT 1441
DFKL+LYD + K I V+DMRD +F+V V +DVIHA + DIP IFRVT
Sbjct: 1097 DFKLFLYDIA---EGKASQPSVVISQVIDMRDEEFSVSSVLASDVIHASRKDIPCIFRVT 1153
Query: 1440 TTQILNXXXXXXXXSKFYTLFMAETEEEKRKWVVALSELKTLLRRSKLADRKAFLVKEVF 1261
+Q+ +K L +A+TE EK KWV LSEL +L+++K DR ++ KE +
Sbjct: 1154 ASQL------SASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSVYVPKEAY 1207
Query: 1260 DVTTLPSIRVAQCCAIIDRSKIVIGFSDHGLYCIEISRQLLIPVGGEKENKQRCVETVEY 1081
D +TLP I+ Q AIID +I +G ++ GL+ + +++ +I VG K+ + +E
Sbjct: 1208 D-STLPLIKTTQAAAIIDHERIALG-NEEGLFVVHVTKDEIIRVGDNKK-----IHQIEL 1260
Query: 1080 DEAEQLLMMIVGPAKDRHVRIVPSAALDGRDLKWIKVNDTKGCHLLAVGTNNPGGRAGFF 901
+QL+ +I G ++RHVR+ P +ALDGR+ + K+++TKGC + G G
Sbjct: 1261 IPNDQLVAVISG--RNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALT-CL 1317
Query: 900 AVAFKKSVTIFQIDRSEKRHKKWKDLAMPGTPQSIAIFNGRLYVGFSHSFRSWSLVGVDS 721
VA K+ V +++ +S+ RH+K+K++ +P Q +AIF+ +L VGF F + L G +
Sbjct: 1318 CVAMKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNG-EG 1376
Query: 720 SPVGSGDASGAVLQHISLVNMEDTSLQFLNQQTSYEAKLIVNVPGSPDEYLLVFNMIGLY 541
+P S+++ D +L F+ Q I V S EYLL FN IG+Y
Sbjct: 1377 NP-------------YSMLHSNDHTLSFIAHQ---PMDAICAVEISSKEYLLCFNSIGIY 1420
Query: 540 VNEMGRRSRLPEVMFPTQAKYFAYHEPYLCVFSENEVDIFNVTLAEWVQTINLRSAKPLS 361
+ GRRSR E+M+P Y+ PYL V+SEN VDIF+V EW+QT+ L+ +PL+
Sbjct: 1421 TDCQGRRSRQQELMWPANPSSCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLN 1480
Query: 360 GDGILSTCLCNDSPIFVLLQNVLQDQDSIEVPVNLASGSTDGXXXXXXXXXXXTIGKDDR 181
+G L+ L ++ + +N + + D + VP + ++
Sbjct: 1481 NEGSLN-LLGLETIRLIYFKNKMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEE 1539
Query: 180 SASERRSHIQ--------ISTPSDFMHIVHMGPAPVMEL 88
+RR ++ IS P++F HI HMGP +++
Sbjct: 1540 RMQQRREMLRDPEMRNKLISNPTNFNHIAHMGPGDGIQI 1578
>gi|29373940|emb|CAD57745.1| CDC42 binding protein kinase alpha
(DMPK-like) [Homo sapiens]
Length = 1719
Score = 1036 bits (2680), Expect = 0.0
Identities = 633/1659 (38%), Positives = 925/1659 (55%), Gaps = 103/1659 (6%)
Frame = -1
Query: 4755 SAPVRLKTLENIYMDGPSK-KPEALSFETLIDSLICLYDECCNSTLRKEKCIAEFVESVK 4579
S VRL+ LE +DGP++ + S ETL+D LICLYDEC NS LR+EK I E++E K
Sbjct: 2 SGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWAK 61
Query: 4578 TVISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETAC 4399
SK K++RL R+DFE+LKVIG+GAFGEVAVV+++ +++AMKILNKWEM+KRAETAC
Sbjct: 62 PFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETAC 121
Query: 4398 FREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFY 4219
FREERDVLV GD +WIT LHYAFQD+ NLY VMDYY+GGD+LTLLSKF D +PE MA+FY
Sbjct: 122 FREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFY 181
Query: 4218 IAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASNVAVGTP 4039
+AEMV+AIDS+H+L YVHRD+KPDN+L+DM GHIRLADFGSCL+++ DG+V S+VAVGTP
Sbjct: 182 LAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTP 241
Query: 4038 DYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDML 3859
DYISPEIL+AMEDG+GRYG ECDWWSLG+CMYEMLYG TPFY+E LV+TYGKIM+H++
Sbjct: 242 DYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERF 301
Query: 3858 DFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIRDSNPPYV 3679
FP D VSE AKDLIR+LICS + R G+NG+ DF+ HPFF GIDW+ IR+ PY+
Sbjct: 302 QFPAQVTD--VSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYI 359
Query: 3678 PEVSSPEDTSNFDVDVCEDDFTPCLQ--ETQPPRVLAAFTGNHLPFVGFSYTHGSLLSDA 3505
PEVSSP DTSNFDVD DD CL+ ET PP AF+G+HLPFVGF+YT +LSD
Sbjct: 360 PEVSSPTDTSNFDVD---DD---CLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDR 413
Query: 3504 RSL-------TDEIRAIAQRCQGDAELMEKSVDGFMVELENEKAELVQKLKEA-QTI--- 3358
L + ++ QR D L ++ + + LE EK EL +KL+E+ QT+
Sbjct: 414 SCLRVTAGPTSLDLDVNVQRTL-DNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQAL 472
Query: 3357 --------------------------IAQHVAENPRSEED------------------RN 3310
+ + V E+ E+ +
Sbjct: 473 QYSTVDGPLTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKA 532
Query: 3309 YESTIAQLKDEIQILNKRL--EDEALAQQQQKPKDEIVAXXXXXXXXXXERNK--QLVME 3142
YE I L+ E + LNK L E L Q ++ KD + +L +
Sbjct: 533 YEKQIKTLQQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQ 592
Query: 3141 KSEIQRELDNINDHLDQVLVEKATVVQQ---RDDMQAELADVGDSLLTEKDSVKRLQDEA 2971
K ++ R + + + +D V+ + ++ Q+ + + EL ++L E ++L++++
Sbjct: 593 KQKLARHVRDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQS 652
Query: 2970 EKAKKQV---ADFXXXXXXXXXXXXXXXXKQEEVTIEARKSVETDDHLSEEVVAAKNTIA 2800
E KQ+ + Q+E+T + + +E EE ++ + I
Sbjct: 653 EHYSKQLENELEGLKQKQISYSPGVCSIEHQQEIT-KLKTDLEKKSIFYEEELSKREGIH 711
Query: 2799 SLQATNEERE------------TEIKKLKQRMDEERASHTAQSEQEMKQLEAHYERAQKM 2656
+ + N ++E EI LK ++++ R ++ E+ + + YER + +
Sbjct: 712 ANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVL 771
Query: 2655 LQDN--------------VEQMNVENRGLRDEIEKLSQQMAALPRGGLNEQQLHEIFNWV 2518
L + E +++ N+ L +E++ L+ + ++ E Q+ EI WV
Sbjct: 772 LTEENKKLTSELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHW---EAQITEIIQWV 828
Query: 2517 SEEKATREEMENLTRKITGEVESLKNNSPLTTSNYIQNTPSGWGSRRMNNVARKDGLDLQ 2338
S+EK R ++ L K+T E+E+L+N+S T + T W RR + L+LQ
Sbjct: 829 SDEKDARGYLQALASKMTEELEALRNSSLGTRA-----TDMPWKMRRFAKLDMSARLELQ 883
Query: 2337 RQLQAEIDAKLKLKAELKNSQEQYLTSAARLDDTEKRMASLMREVAMLKQQKNIENSSDS 2158
L AEI AK ++ EL + + + +L D+EK+ L+ E+ L I+++ +
Sbjct: 884 SALDAEIRAKQAIQEELNKVKASNIITECKLKDSEKKNLELLSEIEQL-----IKDTEEL 938
Query: 2157 AFSSTMGRGDLMISMNNDYEMSNSSLMRQEMISRQSTPSYENAILLHDHQVPKRVDDLRY 1978
+ D S +L + E + STP + LR
Sbjct: 939 RSEKGIEHQDSQHSFLAFLNTPTDALDQFETV--DSTP------------LSVHTPTLRK 984
Query: 1977 KQKPMKTASGIFSPVSISAMERGHNFERMKIKTPTKCGHCTSILIGLDRQGLFCQSCQYA 1798
K P T F P + H F TPTKC CTS+++GL RQG C+ C ++
Sbjct: 985 KGCPGSTG---FPP-----KRKTHQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFS 1036
Query: 1797 CHVSCAERVSQSCPVPEEERR-PLGIDPTRGVGTAYEGLVKTPRAGGVRKGWQTAYVVVC 1621
CH++C + +CPVP E+ + PLGIDP +G+GTAYEG V+ P+ GV+KGWQ A +VC
Sbjct: 1037 CHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPKPAGVKKGWQRALAIVC 1096
Query: 1620 DFKLYLYDCTVDRQNKMQDVKNEIRLVLDMRDPDFTVCGVSEADVIHAQKGDIPKIFRVT 1441
DFKL+LYD + K I V+DMRD +F+V V +DVIHA + DIP IFRVT
Sbjct: 1097 DFKLFLYDIA---EGKASQPSVVISQVIDMRDEEFSVSSVLASDVIHASRKDIPCIFRVT 1153
Query: 1440 TTQILNXXXXXXXXSKFYTLFMAETEEEKRKWVVALSELKTLLRRSKLADRKAFLVKEVF 1261
+Q+ +K L +A+TE EK KWV LSEL +L+++K DR ++ KE +
Sbjct: 1154 ASQL------SASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSVYVPKEAY 1207
Query: 1260 DVTTLPSIRVAQCCAIIDRSKIVIGFSDHGLYCIEISRQLLIPVGGEKENKQRCVETVEY 1081
D +TLP I+ Q AIID +I +G ++ GL+ + +++ +I VG K+ + +E
Sbjct: 1208 D-STLPLIKTTQAAAIIDHERIALG-NEEGLFVVHVTKDEIIRVGDNKK-----IHQIEL 1260
Query: 1080 DEAEQLLMMIVGPAKDRHVRIVPSAALDGRDLKWIKVNDTKGCHLLAVGTNNPGGRAGFF 901
+QL+ +I G ++RHVR+ P +ALDGR+ + K+++TKGC + G G
Sbjct: 1261 IPNDQLVAVISG--RNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALT-CL 1317
Query: 900 AVAFKKSVTIFQIDRSEKRHKKWKDLAMPGTPQSIAIFNGRLYVGFSHSFRSWSLVGVDS 721
VA K+ V +++ +S+ RH+K+K++ +P Q +AIF+ +L VGF F + L G +
Sbjct: 1318 CVAMKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNG-EG 1376
Query: 720 SPVGSGDASGAVLQHISLVNMEDTSLQFLNQQTSYEAKLIVNVPGSPDEYLLVFNMIGLY 541
+P S+++ D +L F+ Q I V S EYLL FN IG+Y
Sbjct: 1377 NP-------------YSMLHSNDHTLSFIAHQ---PMDAICAVEISSKEYLLCFNSIGIY 1420
Query: 540 VNEMGRRSRLPEVMFPTQAKYFAYHEPYLCVFSENEVDIFNVTLAEWVQTINLRSAKPLS 361
+ GRRSR E+M+P Y+ PYL V+SEN VDIF+V EW+QT+ L+ +PL+
Sbjct: 1421 TDCQGRRSRQQELMWPANPSSCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLN 1480
Query: 360 GDGILSTCLCNDSPIFVLLQNVLQDQDSIEVPVNLASGSTDGXXXXXXXXXXXTIGKDDR 181
+G L+ L ++ + +N + + D + VP + ++
Sbjct: 1481 NEGSLN-LLGLETIRLIYFKNKMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEE 1539
Query: 180 SASERRSHIQ--------ISTPSDFMHIVHMGPAPVMEL 88
+RR ++ IS P++F HI HMGP +++
Sbjct: 1540 RMQQRREMLRDPEMRNKLISNPTNFNHIAHMGPGDGIQI 1578
>gi|50756157|ref|XP_415041.1| PREDICTED: similar to CDC42-binding
protein kinase alpha isoform B; ser-thr protein kinase
related to the myotonic dystrophy protein kinase; ser-thr
protein kinase PK428; myotonic dystrophy kinase-related
CDC42-binding protein kinase alpha; CDC42 binidng prot...
[Gallus gallus]
Length = 2136
Score = 1025 bits (2650), Expect = 0.0
Identities = 645/1725 (37%), Positives = 945/1725 (54%), Gaps = 145/1725 (8%)
Frame = -1
Query: 4755 SAPVRLKTLENIYMDGPSK-KPEALSFETLIDSLICLYDECCNSTLRKEKCIAEFVE--- 4588
S VRLK LE +DGP++ + S ETL+D LICLYDEC NS LR+EK I E++E
Sbjct: 2 SGEVRLKQLEQFILDGPTQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWAV 61
Query: 4587 ----------------SVKTVISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEI 4456
K SK K++RL ++DFE+LKVIG+GAFGEVAVV+++ ++
Sbjct: 62 CDCPLFYPAALLIVPADAKPFTSKVKQMRLHKEDFEILKVIGRGAFGEVAVVKLKNADKV 121
Query: 4455 YAMKILNKWEMVKRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDM 4276
+AMKILNKWEM+KRAETACFREERDVLV GD +WIT LHYAFQDE LY VMDYY+GGD+
Sbjct: 122 FAMKILNKWEMLKRAETACFREERDVLVNGDNQWITTLHYAFQDENYLYLVMDYYVGGDL 181
Query: 4275 LTLLSKFVDHIPESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGS 4096
LTLLSKF D +PE MA+FY+AEMV+AIDS+H+L YVHRD+KPDN+L+DM GHIRLADFGS
Sbjct: 182 LTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGS 241
Query: 4095 CLRILADGSVASNVAVGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPF 3916
CL+++ DG+V S+VAVGTPDYISPEIL+AMEDG+G+YG ECDWWSLG+CMYEMLYG TPF
Sbjct: 242 CLKLMEDGTVQSSVAVGTPDYISPEILQAMEDGKGKYGPECDWWSLGVCMYEMLYGETPF 301
Query: 3915 YSERLVDTYGKIMSHQDMLDFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLH 3736
Y + LV+TYGKIM+ ++ FP D VSE AKDLIR+LICS + R G+NG+ DF+ H
Sbjct: 302 YVKSLVETYGKIMNLKERFQFPAQVTD--VSESAKDLIRRLICSREHRLGQNGIEDFKNH 359
Query: 3735 PFFEGIDWNTIRDSNPPYVPEVSSPEDTSNFDVDVCEDDFTPCLQ--ETQPPRVLAAFTG 3562
PFF GIDW+ IR+ + PY+PEVSSP DTSNFDVD DD CL+ ET PP AF+G
Sbjct: 360 PFFAGIDWDNIRNCDAPYIPEVSSPTDTSNFDVD---DD---CLKNSETMPPPSHTAFSG 413
Query: 3561 NHLPFVGFSYTHGSLLSDARSL-------TDEIRAIAQRCQGDAELMEKSVDGFMVELEN 3403
+HLPFVGF+YT +LSD L + ++ A QR D+ L ++ + + LE
Sbjct: 414 HHLPFVGFTYTSSCVLSDRSCLRLTAGPPSMDLDANIQRTLEDS-LATEAYERRIRRLEQ 472
Query: 3402 EKAELVQKLKEA-QTIIA-QHVAENPRSEEDRNYESTIAQLKDEIQILNKRLEDEALAQQ 3229
EK EL +KL+E+ QT+ A Q+ + ++ E I LK+EI+ L K++ D +Q
Sbjct: 473 EKLELSRKLQESTQTVQALQYSTVDGPIAASKDLE--IKSLKEEIEKLKKQVTDSGHLEQ 530
Query: 3228 QQKPKDEIVAXXXXXXXXXXERNKQ---LVMEKSEIQRELDNINDHLDQVLVEKATVVQQ 3058
Q + KQ L E+ ++ +EL +D L E Q
Sbjct: 531 QLEEASTARRELDDASRQIKAFEKQVRTLKQEREDLNKELAESSDRLKSQAKELKDAHSQ 590
Query: 3057 RDDMQAELADVGDSLL---TEKDSVKR----LQDEAEKAKKQVADFXXXXXXXXXXXXXX 2899
R E +++ + L ++K + R ++E E ++V
Sbjct: 591 RKLAMQEFSEMNERLTDLHSQKQKLARQLRDKEEEMEVVMQKVESLRQELRRTERLKKEL 650
Query: 2898 XXKQEEVTIEA---RKSVETDDHLSEEVVAAKNTIASLQ------ATNEERETEIKKLKQ 2746
+ E EA RK E + S+++ + + Q ++ E + EI KLK
Sbjct: 651 EVQAEAAAAEASKDRKLRERSEQYSKQLESEVEGLKQKQIGRSPGVSSIEHQQEITKLKA 710
Query: 2745 RM-------DEERASHTAQSEQEMKQLEAHYERAQK----------MLQDNVEQMNVENR 2617
+ +EE + E+K L+ A+ +L+D +E+ EN+
Sbjct: 711 DLEKKSVFYEEELSKREIMHANEIKSLKKELRDAESQQLALKKEIMILKDKLEKTRRENQ 770
Query: 2616 GLRDEIE-------------------KLSQQMAAL----PRGGLNEQQLH---------- 2536
R+E E KLS ++ L R +N +QL
Sbjct: 771 SEREEFETEFKQKYEREKILLTEENKKLSNELDKLTTMFERLSMNNRQLEEEMRDLADKK 830
Query: 2535 -----------EIFNWVSEEKATREEMENLTRKITGEVESLKNNSPLTTSN------YIQ 2407
EI WVS+EK R ++ L K+T E+E+L+N+S + +I+
Sbjct: 831 ESVAHWEAQITEIIQWVSDEKDARGYLQALASKMTEELEALRNSSLGARATVRLRILHIR 890
Query: 2406 NTPSGWGSRRMNNVARKDGLDLQRQLQAEIDAKLKLKAELKNSQEQYLTSAARLDDTEKR 2227
W RR + L+LQ L AEI AK ++ EL + +++ +L ++EK+
Sbjct: 891 CFDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQDELNKVKASCISTECKLQESEKK 950
Query: 2226 MASLMREVAMLKQQKNIENSSDSAFSSTMGRGDLMISMNNDYE-MSNSSLMRQEMISRQS 2050
L+ ++ LK++ E S+ + + +N + + E + +
Sbjct: 951 NLELLTDIERLKKETE-ELRSEKGVKHQDSQNSFLAFLNAPTSALDQFEIDSVENFTLSN 1009
Query: 2049 TPSYENAILLHDH------QVPKRVDDLRYKQKP--------MKTA---SGIFSPVSISA 1921
TPS + H H ++ + P M+TA SG+ +P
Sbjct: 1010 TPSRDEDTKSHLHSRSRSPSTASEIEPIEVTDHPPRSIHTPTMRTAYIGSGLSAP----- 1064
Query: 1920 MERGHNFERMKIKTPTKCGHCTSILIGLDRQGLFCQSCQYACHVSCAERVSQSCPVPEEE 1741
+ H F TPTKC CTS+++GL RQG C+ C ++CHV+CA++ CP+P E+
Sbjct: 1065 KPKAHQFVVKSFNTPTKCNQCTSLMVGLIRQGCTCEVCGFSCHVTCADKAPAVCPIPPEQ 1124
Query: 1740 RR-PLGIDPTRGVGTAYEGLVKTPRAGGVRKGWQTAYVVVCDFKLYLYDCTVDRQNKMQD 1564
+ PLGIDP +G+GTAYEG V+ P+ GV+KGWQ A V+CDFKL+LYD + ++
Sbjct: 1125 TKGPLGIDPQKGIGTAYEGHVRVPKPAGVKKGWQRALAVICDFKLFLYDIAEGKASQPSV 1184
Query: 1563 VKNEIRLVLDMRDPDFTVCGVSEADVIHAQKGDIPKIFRVTTTQILNXXXXXXXXSKFYT 1384
V ++ V+DMRD +F+V V +DVIHA + DIP IFRVT +Q+ +K
Sbjct: 1185 VVSQ---VIDMRDEEFSVSSVLASDVIHANRKDIPCIFRVTASQL------SATSNKCSI 1235
Query: 1383 LFMAETEEEKRKWVVALSELKTLLRRSKLADRKAFLVKEVFDVTTLPSIRVAQCCAIIDR 1204
L + + E EK KWV L+EL +L+++KL DR ++ KE +D +TLP I+ Q AIID
Sbjct: 1236 LILTDGENEKSKWVGVLNELHRILKKNKLKDRSVYVPKEAYD-STLPLIKTTQSAAIIDH 1294
Query: 1203 SKIVIGFSDHGLYCIEISRQLLIPVGGEKENKQRCVETVEYDEAEQLLMMIVGPAKDRHV 1024
+I +G ++ GL+ + +++ +I VG K+ V +E +EQL+ +I G ++RHV
Sbjct: 1295 ERIALG-NEEGLFVVHVTKDEIIRVGDNKK-----VHQIELIPSEQLIAVISG--RNRHV 1346
Query: 1023 RIVPSAALDGRDLKWIKVNDTKGCHLLAVGTNNPGGRAGFFAVAFKKSVTIFQIDRSEKR 844
R+ P ALDGR+ ++ K+ +TKGC + G G VA K+ V +++++S+ R
Sbjct: 1347 RLFPMTALDGRETEFYKLAETKGCQSIVSGHVRHGALT-CLCVAMKRQVLCYELNQSKTR 1405
Query: 843 HKKWKDLAMPGTPQSIAIFNGRLYVGFSHSFRSWSLVGVDSSPVGSGDASGAVLQHISLV 664
HKK K++ + G Q +++F+ RL VG+ F L G + SP SL+
Sbjct: 1406 HKKIKEIQVQGNVQWMSVFSERLCVGYQSGFLKHPLHG-EGSP-------------YSLL 1451
Query: 663 NMEDTSLQFLNQQTSYEAKLIVNVPGSPDEYLLVFNMIGLYVNEMGRRSRLPEVMFPTQA 484
+ +D +L F++QQ + I V S EYLL F+ +G+YV+ GRRSR E+M+P
Sbjct: 1452 HPDDHTLSFISQQPT---DAICAVEISNKEYLLCFSSVGVYVDCQGRRSRQQELMWPATP 1508
Query: 483 KYFAYHEPYLCVFSENEVDIFNVTLAEWVQTINLRSAKPLSGDGILSTCLCNDSPIFVLL 304
Y+ PYL V+SEN +DIF+V EW+QTI L+ +PL+ +G L+ L ++ +
Sbjct: 1509 SSCCYNAPYLSVYSENAIDIFDVNSMEWIQTIPLKKVRPLNTEGSLN-LLGLETVRLIYF 1567
Query: 303 QNVLQDQDSIEVPVNLASGSTDGXXXXXXXXXXXTIGKDDRSASERRSHIQ--------I 148
+N + + D + VP + ++ +RR ++ I
Sbjct: 1568 KNKMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNKLI 1627
Query: 147 STPSDFMHIVHMGPAPVMELQQNF-IDLQSNHSHTSSDKDSLNRS 16
S P++F HI HMGP +++ ++ + Q +H K+ R+
Sbjct: 1628 SNPTNFNHIAHMGPGDGIQILKDLPMQQQGQQAHVIPCKEGAQRT 1672
>gi|5006445|gb|AAD37506.1| CDC42-binding protein kinase beta [Homo
sapiens]
Length = 1711
Score = 1001 bits (2587), Expect = 0.0
Identities = 615/1660 (37%), Positives = 923/1660 (55%), Gaps = 104/1660 (6%)
Frame = -1
Query: 4755 SAPVRLKTLENIYMDGPSKKPEALSFETLIDSLICLYDECCNSTLRKEKCIAEFVESVKT 4576
SA VRLK LE + +DGP + ALS ETL+D L+CLY EC +S LR++K +AEF+E K
Sbjct: 2 SAKVRLKKLEQLLLDGPWRNESALSVETLLDVLVCLYTECSHSALRRDKYVAEFLEWAKP 61
Query: 4575 VISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACF 4396
K+++L R+DFE++KVIG+GAFGEVAVV+M+ IYAMKILNKWEM+KRAETACF
Sbjct: 62 FTQLVKEMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACF 121
Query: 4395 REERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFYI 4216
REERDVLV GD +WIT LHYAFQDE +LY VMDYY+GGD+LTLLSKF D +PE MA+FYI
Sbjct: 122 REERDVLVNGDCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYI 181
Query: 4215 AEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASNVAVGTPD 4036
EMVLAIDS+H+L YVHRD+KPDNVLLD+ GHIRLADFGSCL++ DG+V S+VAVGTPD
Sbjct: 182 GEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPD 241
Query: 4035 YISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDMLD 3856
YISPEIL+AMEDG G+YG ECDWWSLG+CMYEMLYG TPFY+E LV+TYGKIM+H++
Sbjct: 242 YISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQ 301
Query: 3855 FPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIRDSNPPYVP 3676
FP D VSEEAKDLI++LICS + R G+NG+ DF+ H FFEG++W IR+ PY+P
Sbjct: 302 FPSHVTD--VSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIP 359
Query: 3675 EVSSPEDTSNFDVDVCEDDFTPCLQETQ--PPRVLAAFTGNHLPFVGFSYTHGSLLSDAR 3502
+VSSP DTSNFDVD DD L+ T+ PP F+G HLPF+GF++T S SD
Sbjct: 360 DVSSPSDTSNFDVD---DD---VLRNTEILPPGSHTGFSGLHLPFIGFTFTTESCFSDRG 413
Query: 3501 SLTDEIRAIA----QRCQGDAE--LMEKSVDGFMVELENEKAELVQKLKEA-QTIIAQH- 3346
SL +++ + Q D E L ++ + + LE EK EL +KL+E+ QT+ + H
Sbjct: 414 SLKSIMQSNTLTKDEDVQRDLEHSLQMEAYERRIRRLEQEKLELSRKLQESTQTVQSLHG 473
Query: 3345 ----VAENPRSEEDRNYESTIAQLKDEI---QILNKRLEDEALAQQQ------------- 3226
++ + R +E + I +LK++I L ++LED +Q+
Sbjct: 474 SSRALSNSNRDKEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEK 533
Query: 3225 -----QKPKDEIVAXXXXXXXXXXERNKQLV---MEKSEIQRELDNINDHLDQVLVEKAT 3070
++ K+E+ + K+L ++ +E +N+ + ++ +K
Sbjct: 534 QHRVVRQEKEELHKQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQK 593
Query: 3069 VVQQRDD------------------------MQAELADVGDSLLTEKDSVKRLQDEAEKA 2962
V +Q D ++ EL D + E ++L++ +E
Sbjct: 594 VSRQLRDKEEEMEVATQKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERKLREHSENF 653
Query: 2961 KKQVADFXXXXXXXXXXXXXXXXKQEEVTIEARKS-VETDDHLSEEVVAAKNTIASLQAT 2785
KQ+ + + I KS +E EE + + L+
Sbjct: 654 CKQMESELEALKVKQGGRGAGATLEHQQEISKIKSELEKKVLFYEEELVRREASHVLEVK 713
Query: 2784 NEERET------------EIKKLKQRMDEERASHTAQSEQEMKQLEAHYERAQKMLQDN- 2644
N ++E EI LK ++++ + + E+ + ++ YER + ML D
Sbjct: 714 NVKKEVHDSESHQLALQKEILMLKDKLEKSKRERHNEMEEAVGTIKDKYERERAMLFDEN 773
Query: 2643 -------------VEQMNVENRGLRDEIEKLSQQMAALPRGGLNEQQLHEIFNWVSEEKA 2503
V+++ +NR L DE++ L+ + ++ E Q+ EI WVS+EK
Sbjct: 774 KKLTAENEKLCSFVDKLTAQNRQLEDELQDLAAKKESVAHW---EAQIAEIIQWVSDEKD 830
Query: 2502 TREEMENLTRKITGEVESLKNNSPLTTSNYIQNTPSGWGSRRMNNVARKDGLDLQRQLQA 2323
R ++ L K+T E+E+L+++S + + W RR + L+LQ L+A
Sbjct: 831 ARGYLQALASKMTEELEALRSSSLGS-----RTLDPLWKVRRSQKLDMSARLELQSALEA 885
Query: 2322 EIDAKLKLKAELKNSQEQYLTSAARLDDTEKRMASLMREVAMLKQQKNIENSSDSAFSST 2143
EI AK ++ EL+ ++ LT ++L D+E + L+ E+ +LK++ + +D+
Sbjct: 886 EIRAKQLVQEELRKVKDANLTLESKLKDSEAKNRELLEEMEILKKKMEEKFRADTGLKLP 945
Query: 2142 MGRGDLMISMN-----NDYEMSNSSLMRQEMISRQSTPSYENAILLHDHQVPKRVDDLRY 1978
+ + N +D SS QE + + S ++ + Q R
Sbjct: 946 DFQDSIFEYFNTAPLAHDLTFRTSSASEQETQAPKPEASPSMSVAASEQQEDMARPPQRP 1005
Query: 1977 KQKPMKTASGIFSPVSISAMERGHNFERMKIKTPTKCGHCTSILIGLDRQGLFCQSCQYA 1798
P+ T + V + H F +PT+C HCTS+++GL RQG C+ C +A
Sbjct: 1006 SAVPLPTTQAL---VLAGPKPKAHQFSIKSFSSPTQCSHCTSLMVGLIRQGYACEVCSFA 1062
Query: 1797 CHVSCAERVSQSCPV-PEEERRPLGIDPTRGVGTAYEGLVKTPRAGGVRKGWQTAYVVVC 1621
CHVSC + Q CP+ PE+ +RPLG+D RG+GTAY+G VK P+ GV+KGWQ AY VVC
Sbjct: 1063 CHVSCKDGAPQVCPIPPEQSKRPLGVDVQRGIGTAYKGHVKVPKPTGVKKGWQRAYAVVC 1122
Query: 1620 DFKLYLYDCTVDRQNKMQDVKNEIRLVLDMRDPDFTVCGVSEADVIHAQKGDIPKIFRVT 1441
+ KL+LYD + + + ++ VLD+RD +F+V V +DVIHA + DIP IFRVT
Sbjct: 1123 ECKLFLYDLPEGKSTQPGVIASQ---VLDLRDDEFSVSSVLASDVIHATRRDIPCIFRVT 1179
Query: 1440 TTQILNXXXXXXXXSKFYTLFMAETEEEKRKWVVALSELKTLLRRSKLADRKAFLVKEVF 1261
+ +L L + E E EKRKWV L L+++L +++L ++ + E +
Sbjct: 1180 AS-LLGAPSKTSS-----LLILTENENEKRKWVGILEGLQSILHKNRLRNQVVHVPLEAY 1233
Query: 1260 DVTTLPSIRVAQCCAIIDRSKIVIGFSDHGLYCIEISRQLLIPVGGEKENKQRCVETVEY 1081
D ++LP I+ AI+D +I +G + GLY IE++R +++ K+ V +E
Sbjct: 1234 D-SSLPLIKAILTAAIVDADRIAVGL-EEGLYVIEVTRDVIVRAADCKK-----VHQIEL 1286
Query: 1080 DEAEQLLMMIVGPAKDRHVRIVPSAALDGRDLKW-IKVNDTKGCHLLAVGTNNPGGRAGF 904
E++++++ G ++ HV + P ++LDG + + IK+ +TKGC L+A T
Sbjct: 1287 APREKIVILLCG--RNHHVHLYPWSSLDGAEGSFDIKLPETKGCQLMATATLKRNSGTCL 1344
Query: 903 FAVAFKKSVTIFQIDRSEKRHKKWKDLAMPGTPQSIAIFNGRLYVGFSHSFRSWSLVGVD 724
F VA K+ + ++I R++ H+K+ ++ PG+ Q +A+ RL VG+ F S+ G D
Sbjct: 1345 F-VAVKRLILCYEIQRTKPFHRKFNEIVAPGSVQCLAVLRDRLCVGYPSGFCLLSIQG-D 1402
Query: 723 SSPVGSGDASGAVLQHISLVNMEDTSLQFLNQQTSYEAKLIVNVPGSPDEYLLVFNMIGL 544
P ++LVN D SL FL+QQ S++A V + +EYLL F+ +GL
Sbjct: 1403 GQP-------------LNLVNPNDPSLAFLSQQ-SFDALCAVEL--ESEEYLLCFSHMGL 1446
Query: 543 YVNEMGRRSRLPEVMFPTQAKYFAYHEPYLCVFSENEVDIFNVTLAEWVQTINLRSAKPL 364
YV+ GRR+R E+M+P + ++ V+SE VD+F+V EWVQTI LR +PL
Sbjct: 1447 YVDPQGRRARAQELMWPAAPVACSCSPTHVTVYSEYGVDVFDVRTMEWVQTIGLRRIRPL 1506
Query: 363 SGDGILSTCLCNDSPIFVLLQNVLQDQDSIEVPVNLASGSTDGXXXXXXXXXXXTIGKDD 184
+ +G L+ C + P + ++ + VP + + +++
Sbjct: 1507 NSEGTLNLLNC-EPPRLIYFKSKFSGA-VLNVPDTSDNSKKQMLRTRSKRRFVFKVPEEE 1564
Query: 183 RSASERRSHIQ--------ISTPSDFMHIVHMGPAPVMEL 88
R +RR ++ IS P++F H+ HMGP M++
Sbjct: 1565 R-LQQRREMLRDPELRSKMISNPTNFNHVAHMGPGDGMQV 1603
>gi|14133241|dbj|BAA86438.2| KIAA1124 protein [Homo sapiens]
Length = 1760
Score = 999 bits (2584), Expect = 0.0
Identities = 614/1660 (36%), Positives = 922/1660 (54%), Gaps = 104/1660 (6%)
Frame = -1
Query: 4755 SAPVRLKTLENIYMDGPSKKPEALSFETLIDSLICLYDECCNSTLRKEKCIAEFVESVKT 4576
SA VRLK LE + +DGP + ALS ETL+D L+CLY EC +S LR++K +AEF+E K
Sbjct: 51 SAKVRLKKLEQLLLDGPWRNESALSVETLLDVLVCLYTECSHSALRRDKYVAEFLEWAKP 110
Query: 4575 VISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACF 4396
K+++L R+DFE++KVIG+GAFGEVAVV+M+ IYAMKILNKWEM+KRAETACF
Sbjct: 111 FTQLVKEMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACF 170
Query: 4395 REERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFYI 4216
REERDVLV GD +WIT LHYAFQDE +LY VMDYY+GGD+LTLLSKF D +PE MA+FYI
Sbjct: 171 REERDVLVNGDCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYI 230
Query: 4215 AEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASNVAVGTPD 4036
EMVLAIDS+H+L YVHRD+KPDNVLLD+ GHIRLADFGSCL++ DG+V S+VAVGTPD
Sbjct: 231 GEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPD 290
Query: 4035 YISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDMLD 3856
YISPEIL+AMEDG G+YG ECDWWSLG+CMYEMLYG TPFY+E LV+TYGKIM+H++
Sbjct: 291 YISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQ 350
Query: 3855 FPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIRDSNPPYVP 3676
FP D VSEEAKDLI++LICS + R G+NG+ DF+ H FFEG++W IR+ PY+P
Sbjct: 351 FPSHVTD--VSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIP 408
Query: 3675 EVSSPEDTSNFDVDVCEDDFTPCLQETQ--PPRVLAAFTGNHLPFVGFSYTHGSLLSDAR 3502
+VSSP DTSNFDVD DD L+ T+ PP F+G HLPF+GF++T S SD
Sbjct: 409 DVSSPSDTSNFDVD---DD---VLRNTEILPPGSHTGFSGLHLPFIGFTFTTESCFSDRG 462
Query: 3501 SLTDEIRAIA----QRCQGDAE--LMEKSVDGFMVELENEKAELVQKLKEA-QTIIAQH- 3346
SL +++ + Q D E L ++ + + LE EK EL +KL+E+ QT+ + H
Sbjct: 463 SLKSIMQSNTLTKDEDVQRDLEHSLQMEAYERRIRRLEQEKLELSRKLQESTQTVQSLHG 522
Query: 3345 ----VAENPRSEEDRNYESTIAQLKDEI---QILNKRLEDEALAQQQ------------- 3226
++ + R +E + I +LK++I L ++LED +Q+
Sbjct: 523 SSRALSNSNRDKEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEK 582
Query: 3225 -----QKPKDEIVAXXXXXXXXXXERNKQLV---MEKSEIQRELDNINDHLDQVLVEKAT 3070
++ K+E+ + K+L ++ +E +N+ + ++ +K
Sbjct: 583 QHRVVRQEKEELHKQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQK 642
Query: 3069 VVQQRDD------------------------MQAELADVGDSLLTEKDSVKRLQDEAEKA 2962
V +Q D ++ EL D + E ++L++ +E
Sbjct: 643 VSRQLRDKEEEMEVATQKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERKLREHSENF 702
Query: 2961 KKQVADFXXXXXXXXXXXXXXXXKQEEVTIEARKS-VETDDHLSEEVVAAKNTIASLQAT 2785
KQ+ + + I KS +E EE + + L+
Sbjct: 703 CKQMESELEALKVKQGGRGAGATLEHQQEISKIKSELEKKVLFYEEELVRREASHVLEVK 762
Query: 2784 NEERET------------EIKKLKQRMDEERASHTAQSEQEMKQLEAHYERAQKMLQDN- 2644
N ++E EI LK ++++ + + E+ + ++ YER + ML D
Sbjct: 763 NVKKEVHDSESHQLALQKEILMLKDKLEKSKRERHNEMEEAVGTIKDKYERERAMLFDEN 822
Query: 2643 -------------VEQMNVENRGLRDEIEKLSQQMAALPRGGLNEQQLHEIFNWVSEEKA 2503
V+++ +NR L DE++ L+ + ++ E Q+ EI WVS+EK
Sbjct: 823 KKLTAENEKLCSFVDKLTAQNRQLEDELQDLAAKKESVAHW---EAQIAEIIQWVSDEKD 879
Query: 2502 TREEMENLTRKITGEVESLKNNSPLTTSNYIQNTPSGWGSRRMNNVARKDGLDLQRQLQA 2323
R ++ L K+T E+E+L+++S + + W RR + L+LQ L+A
Sbjct: 880 ARGYLQALASKMTEELEALRSSSLGS-----RTLDPLWKVRRSQKLDMSARLELQSALEA 934
Query: 2322 EIDAKLKLKAELKNSQEQYLTSAARLDDTEKRMASLMREVAMLKQQKNIENSSDSAFSST 2143
EI AK ++ EL+ ++ LT ++L D+E + L+ E+ +LK++ + +D+
Sbjct: 935 EIRAKQLVQEELRKVKDANLTLESKLKDSEAKNRELLEEMEILKKKMEEKFRADTGLKLP 994
Query: 2142 MGRGDLMISMN-----NDYEMSNSSLMRQEMISRQSTPSYENAILLHDHQVPKRVDDLRY 1978
+ + N +D SS QE + + S ++ + Q R
Sbjct: 995 DFQDSIFEYFNTAPLAHDLTFRTSSASEQETQAPKPEASPSMSVAASEQQEDMARPPQRP 1054
Query: 1977 KQKPMKTASGIFSPVSISAMERGHNFERMKIKTPTKCGHCTSILIGLDRQGLFCQSCQYA 1798
P+ T + + H F +PT+C HCTS+++GL RQG C+ C +A
Sbjct: 1055 SAVPLPTTQAL---ALAGPKPKAHQFSIKSFSSPTQCSHCTSLMVGLIRQGYACEVCSFA 1111
Query: 1797 CHVSCAERVSQSCPV-PEEERRPLGIDPTRGVGTAYEGLVKTPRAGGVRKGWQTAYVVVC 1621
CHVSC + Q CP+ PE+ +RPLG+D RG+GTAY+G VK P+ GV+KGWQ AY VVC
Sbjct: 1112 CHVSCKDGAPQVCPIPPEQSKRPLGVDVQRGIGTAYKGHVKVPKPTGVKKGWQRAYAVVC 1171
Query: 1620 DFKLYLYDCTVDRQNKMQDVKNEIRLVLDMRDPDFTVCGVSEADVIHAQKGDIPKIFRVT 1441
D KL+LYD + + + ++ VLD+RD +F+V V +DVIHA + DIP IFRVT
Sbjct: 1172 DCKLFLYDLPEGKSTQPGVIASQ---VLDLRDDEFSVSSVLASDVIHATRRDIPCIFRVT 1228
Query: 1440 TTQILNXXXXXXXXSKFYTLFMAETEEEKRKWVVALSELKTLLRRSKLADRKAFLVKEVF 1261
+ +L L + E E EK+KWV L L+++L +++L ++ + E +
Sbjct: 1229 AS-LLGAPSKTSS-----LLILTENENEKKKWVGILEGLQSILHKNRLRNQVVHVPLEAY 1282
Query: 1260 DVTTLPSIRVAQCCAIIDRSKIVIGFSDHGLYCIEISRQLLIPVGGEKENKQRCVETVEY 1081
D ++LP I+ AI+D +I +G + GLY IE++R +++ K+ V +E
Sbjct: 1283 D-SSLPLIKAILTAAIVDADRIAVGL-EEGLYVIEVTRDVIVRAADCKK-----VHQIEL 1335
Query: 1080 DEAEQLLMMIVGPAKDRHVRIVPSAALDGRDLKW-IKVNDTKGCHLLAVGTNNPGGRAGF 904
E++++++ G ++ HV + P ++LDG + + IK+ +TKGC L+A T
Sbjct: 1336 APREKIVILLCG--RNHHVHLYPWSSLDGAEGSFDIKLPETKGCQLMATATLKRNSGTCL 1393
Query: 903 FAVAFKKSVTIFQIDRSEKRHKKWKDLAMPGTPQSIAIFNGRLYVGFSHSFRSWSLVGVD 724
F VA K+ + ++I R++ H+K+ ++ PG+ Q +A+ RL VG+ F S+ G D
Sbjct: 1394 F-VAVKRLILCYEIQRTKPFHRKFNEIVAPGSVQCLAVLRDRLCVGYPSGFCLLSIQG-D 1451
Query: 723 SSPVGSGDASGAVLQHISLVNMEDTSLQFLNQQTSYEAKLIVNVPGSPDEYLLVFNMIGL 544
P ++LVN D SL FL+QQ S++A V + +EYLL F+ +GL
Sbjct: 1452 GQP-------------LNLVNPNDPSLAFLSQQ-SFDALCAVEL--ESEEYLLCFSHMGL 1495
Query: 543 YVNEMGRRSRLPEVMFPTQAKYFAYHEPYLCVFSENEVDIFNVTLAEWVQTINLRSAKPL 364
YV+ GRR+R E+M+P + ++ V+SE VD+F+V EWVQTI LR +PL
Sbjct: 1496 YVDPQGRRARAQELMWPAAPVACSCSPTHVTVYSEYGVDVFDVRTMEWVQTIGLRRIRPL 1555
Query: 363 SGDGILSTCLCNDSPIFVLLQNVLQDQDSIEVPVNLASGSTDGXXXXXXXXXXXTIGKDD 184
+ +G L+ C + P + ++ + VP + + +++
Sbjct: 1556 NSEGTLNLLNC-EPPRLIYFKSKFSGA-VLNVPDTSDNSKKQMLRTRSKRRFVFKVPEEE 1613
Query: 183 RSASERRSHIQ--------ISTPSDFMHIVHMGPAPVMEL 88
R +RR ++ IS P++F H+ HMGP M++
Sbjct: 1614 R-LQQRREMLRDPELRSKMISNPTNFNHVAHMGPGDGMQV 1652
>gi|16357474|ref|NP_006026.2| CDC42-binding protein kinase beta;
CDC42-binding protein kinase beta (DMPK-like); MRCK beta;
DMPK-like [Homo sapiens]
Length = 1711
Score = 999 bits (2583), Expect = 0.0
Identities = 614/1660 (36%), Positives = 922/1660 (54%), Gaps = 104/1660 (6%)
Frame = -1
Query: 4755 SAPVRLKTLENIYMDGPSKKPEALSFETLIDSLICLYDECCNSTLRKEKCIAEFVESVKT 4576
SA VRLK LE + +DGP + ALS ETL+D L+CLY EC +S LR++K +AEF+E K
Sbjct: 2 SAKVRLKKLEQLLLDGPWRNESALSVETLLDVLVCLYTECSHSALRRDKYVAEFLEWAKP 61
Query: 4575 VISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACF 4396
K+++L R+DFE++KVIG+GAFGEVAVV+M+ IYAMKILNKWEM+KRAETACF
Sbjct: 62 FTQLVKEMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACF 121
Query: 4395 REERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFYI 4216
REERDVLV GD +WIT LHYAFQDE +LY VMDYY+GGD+LTLLSKF D +PE MA+FYI
Sbjct: 122 REERDVLVNGDCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYI 181
Query: 4215 AEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASNVAVGTPD 4036
EMVLAIDS+H+L YVHRD+KPDNVLLD+ GHIRLADFGSCL++ DG+V S+VAVGTPD
Sbjct: 182 GEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPD 241
Query: 4035 YISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDMLD 3856
YISPEIL+AMEDG G+YG ECDWWSLG+CMYEMLYG TPFY+E LV+TYGKIM+H++
Sbjct: 242 YISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQ 301
Query: 3855 FPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIRDSNPPYVP 3676
FP D VSEEAKDLI++LICS + R G+NG+ DF+ H FFEG++W IR+ PY+P
Sbjct: 302 FPSHVTD--VSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIP 359
Query: 3675 EVSSPEDTSNFDVDVCEDDFTPCLQETQ--PPRVLAAFTGNHLPFVGFSYTHGSLLSDAR 3502
+VSSP DTSNFDVD DD L+ T+ PP F+G HLPF+GF++T S SD
Sbjct: 360 DVSSPSDTSNFDVD---DD---VLRNTEILPPGSHTGFSGLHLPFIGFTFTTESCFSDRG 413
Query: 3501 SLTDEIRAIA----QRCQGDAE--LMEKSVDGFMVELENEKAELVQKLKEA-QTIIAQH- 3346
SL +++ + Q D E L ++ + + LE EK EL +KL+E+ QT+ + H
Sbjct: 414 SLKSIMQSNTLTKDEDVQRDLEHSLQMEAYERRIRRLEQEKLELSRKLQESTQTVQSLHG 473
Query: 3345 ----VAENPRSEEDRNYESTIAQLKDEI---QILNKRLEDEALAQQQ------------- 3226
++ + R +E + I +LK++I L ++LED +Q+
Sbjct: 474 SSRALSNSNRDKEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEK 533
Query: 3225 -----QKPKDEIVAXXXXXXXXXXERNKQLV---MEKSEIQRELDNINDHLDQVLVEKAT 3070
++ K+E+ + K+L ++ +E +N+ + ++ +K
Sbjct: 534 QHRVVRQEKEELHKQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQK 593
Query: 3069 VVQQRDD------------------------MQAELADVGDSLLTEKDSVKRLQDEAEKA 2962
V +Q D ++ EL D + E ++L++ +E
Sbjct: 594 VSRQLRDKEEEMEVATQKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERKLREHSENF 653
Query: 2961 KKQVADFXXXXXXXXXXXXXXXXKQEEVTIEARKS-VETDDHLSEEVVAAKNTIASLQAT 2785
KQ+ + + I KS +E EE + + L+
Sbjct: 654 CKQMESELEALKVKQGGRGAGATLEHQQEISKIKSELEKKVLFYEEELVRREASHVLEVK 713
Query: 2784 NEERET------------EIKKLKQRMDEERASHTAQSEQEMKQLEAHYERAQKMLQDN- 2644
N ++E EI LK ++++ + + E+ + ++ YER + ML D
Sbjct: 714 NVKKEVHDSESHQLALQKEILMLKDKLEKSKRERHNEMEEAVGTIKDKYERERAMLFDEN 773
Query: 2643 -------------VEQMNVENRGLRDEIEKLSQQMAALPRGGLNEQQLHEIFNWVSEEKA 2503
V+++ +NR L DE++ L+ + ++ E Q+ EI WVS+EK
Sbjct: 774 KKLTAENEKLCSFVDKLTAQNRQLEDELQDLAAKKESVAHW---EAQIAEIIQWVSDEKD 830
Query: 2502 TREEMENLTRKITGEVESLKNNSPLTTSNYIQNTPSGWGSRRMNNVARKDGLDLQRQLQA 2323
R ++ L K+T E+E+L+++S + + W RR + L+LQ L+A
Sbjct: 831 ARGYLQALASKMTEELEALRSSSLGS-----RTLDPLWKVRRSQKLDMSARLELQSALEA 885
Query: 2322 EIDAKLKLKAELKNSQEQYLTSAARLDDTEKRMASLMREVAMLKQQKNIENSSDSAFSST 2143
EI AK ++ EL+ ++ LT ++L D+E + L+ E+ +LK++ + +D+
Sbjct: 886 EIRAKQLVQEELRKVKDANLTLESKLKDSEAKNRELLEEMEILKKKMEEKFRADTGLKLP 945
Query: 2142 MGRGDLMISMN-----NDYEMSNSSLMRQEMISRQSTPSYENAILLHDHQVPKRVDDLRY 1978
+ + N +D SS QE + + S ++ + Q R
Sbjct: 946 DFQDSIFEYFNTAPLAHDLTFRTSSASEQETQAPKPEASPSMSVAASEQQEDMARPPQRP 1005
Query: 1977 KQKPMKTASGIFSPVSISAMERGHNFERMKIKTPTKCGHCTSILIGLDRQGLFCQSCQYA 1798
P+ T + + H F +PT+C HCTS+++GL RQG C+ C +A
Sbjct: 1006 SAVPLPTTQAL---ALAGPKPKAHQFSIKSFSSPTQCSHCTSLMVGLIRQGYACEVCSFA 1062
Query: 1797 CHVSCAERVSQSCPV-PEEERRPLGIDPTRGVGTAYEGLVKTPRAGGVRKGWQTAYVVVC 1621
CHVSC + Q CP+ PE+ +RPLG+D RG+GTAY+G VK P+ GV+KGWQ AY VVC
Sbjct: 1063 CHVSCKDGAPQVCPIPPEQSKRPLGVDVQRGIGTAYKGHVKVPKPTGVKKGWQRAYAVVC 1122
Query: 1620 DFKLYLYDCTVDRQNKMQDVKNEIRLVLDMRDPDFTVCGVSEADVIHAQKGDIPKIFRVT 1441
+ KL+LYD + + + ++ VLD+RD +F+V V +DVIHA + DIP IFRVT
Sbjct: 1123 ECKLFLYDLPEGKSTQPGVIASQ---VLDLRDDEFSVSSVLASDVIHATRRDIPCIFRVT 1179
Query: 1440 TTQILNXXXXXXXXSKFYTLFMAETEEEKRKWVVALSELKTLLRRSKLADRKAFLVKEVF 1261
+ +L L + E E EKRKWV L L+++L +++L ++ + E +
Sbjct: 1180 AS-LLGAPSKTSS-----LLILTENENEKRKWVGILEGLQSILHKNRLRNQVVHVPLEAY 1233
Query: 1260 DVTTLPSIRVAQCCAIIDRSKIVIGFSDHGLYCIEISRQLLIPVGGEKENKQRCVETVEY 1081
D ++LP I+ AI+D +I +G + GLY IE++R +++ K+ V +E
Sbjct: 1234 D-SSLPLIKAILTAAIVDADRIAVGL-EEGLYVIEVTRDVIVRAADCKK-----VHQIEL 1286
Query: 1080 DEAEQLLMMIVGPAKDRHVRIVPSAALDGRDLKW-IKVNDTKGCHLLAVGTNNPGGRAGF 904
E++++++ G ++ HV + P ++LDG + + IK+ +TKGC L+A T
Sbjct: 1287 APREKIVILLCG--RNHHVHLYPWSSLDGAEGSFDIKLPETKGCQLMATATLKRNSGTCL 1344
Query: 903 FAVAFKKSVTIFQIDRSEKRHKKWKDLAMPGTPQSIAIFNGRLYVGFSHSFRSWSLVGVD 724
F VA K+ + ++I R++ H+K+ ++ PG+ Q +A+ RL VG+ F S+ G D
Sbjct: 1345 F-VAVKRLILCYEIQRTKPFHRKFNEIVAPGSVQCLAVLRDRLCVGYPSGFCLLSIQG-D 1402
Query: 723 SSPVGSGDASGAVLQHISLVNMEDTSLQFLNQQTSYEAKLIVNVPGSPDEYLLVFNMIGL 544
P ++LVN D SL FL+QQ S++A V + +EYLL F+ +GL
Sbjct: 1403 GQP-------------LNLVNPNDPSLAFLSQQ-SFDALCAVEL--ESEEYLLCFSHMGL 1446
Query: 543 YVNEMGRRSRLPEVMFPTQAKYFAYHEPYLCVFSENEVDIFNVTLAEWVQTINLRSAKPL 364
YV+ GRR+R E+M+P + ++ V+SE VD+F+V EWVQTI LR +PL
Sbjct: 1447 YVDPQGRRARAQELMWPAAPVACSCSPTHVTVYSEYGVDVFDVRTMEWVQTIGLRRIRPL 1506
Query: 363 SGDGILSTCLCNDSPIFVLLQNVLQDQDSIEVPVNLASGSTDGXXXXXXXXXXXTIGKDD 184
+ +G L+ C + P + ++ + VP + + +++
Sbjct: 1507 NSEGTLNLLNC-EPPRLIYFKSKFSGA-VLNVPDTSDNSKKQMLRTRSKRRFVFKVPEEE 1564
Query: 183 RSASERRSHIQ--------ISTPSDFMHIVHMGPAPVMEL 88
R +RR ++ IS P++F H+ HMGP M++
Sbjct: 1565 R-LQQRREMLRDPELRSKMISNPTNFNHVAHMGPGDGMQV 1603
>gi|33942081|ref|NP_898837.1| Cdc42 binding protein kinase beta [Mus
musculus]
gi|30841496|gb|AAP34402.1| CDC42-binding protein kinase beta [Mus
musculus]
Length = 1713
Score = 998 bits (2580), Expect = 0.0
Identities = 615/1664 (36%), Positives = 918/1664 (54%), Gaps = 108/1664 (6%)
Frame = -1
Query: 4755 SAPVRLKTLENIYMDGPSKKPEALSFETLIDSLICLYDECCNSTLRKEKCIAEFVESVKT 4576
SA VRLK LE + +DGP + ALS ETL+D L+CLY EC +S LR++K +AEF+E K
Sbjct: 2 SAKVRLKKLEQLLLDGPWRNDSALSVETLLDVLVCLYTECSHSALRRDKYVAEFLEWAKP 61
Query: 4575 VISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACF 4396
K ++L R+DFE++KVIG+GAFGEVAVV+MR IYAMKILNKWEM+KRAETACF
Sbjct: 62 FTQLVKDMQLHREDFEIIKVIGRGAFGEVAVVKMRNTERIYAMKILNKWEMLKRAETACF 121
Query: 4395 REERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFYI 4216
REERDVLV GD +WIT LHYAFQDE LY VMDYY+GGD+LTLLSKF D +PE MA+FYI
Sbjct: 122 REERDVLVNGDCQWITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYI 181
Query: 4215 AEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASNVAVGTPD 4036
EMVLAIDS+H+L YVHRD+KPDNVLLD+ GHIRLADFGSCL++ DG+V S+VAVGTPD
Sbjct: 182 GEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPD 241
Query: 4035 YISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDMLD 3856
YISPEIL+AMEDG G+YG ECDWWSLG+CMYEMLYG TPFY+E LV+TYGKIM+H++
Sbjct: 242 YISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQ 301
Query: 3855 FPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIRDSNPPYVP 3676
FP D VSEEAKDLI++LICS + R G+NG+ DF+ H FFEG++W IR+ PY+P
Sbjct: 302 FPSHVTD--VSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIP 359
Query: 3675 EVSSPEDTSNFDVDVCEDDFTPCLQETQPPRVLAAFTGNHLPFVGFSYTHGSLLSDARSL 3496
+VSSP DTSNFDVD DD + E PP F+G HLPF+GF++T S SD SL
Sbjct: 360 DVSSPSDTSNFDVD---DDMLRNI-EILPPGSHTGFSGLHLPFIGFTFTTESCFSDRGSL 415
Query: 3495 TDEIRAIA----QRCQGDAE--LMEKSVDGFMVELENEKAELVQKLKEA-QTIIAQH--- 3346
++ + Q D E L ++ + + LE EK EL +KL+E+ QT+ + H
Sbjct: 416 KSMTQSNTLTKDEDVQRDLENSLQIEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGST 475
Query: 3345 --VAENPRSEEDRNYESTIAQLKDEI---QILNKRLEDEALAQQQ--------------- 3226
+ + R +E + + ++K ++ L ++LED +Q+
Sbjct: 476 RALGNSNRDKEIKRLNEELERMKSKMADSNRLERQLEDTVTLRQEHEDSTHRLKGLEKQY 535
Query: 3225 ---QKPKDEIVAXXXXXXXXXXERNKQLV---MEKSEIQRELDNINDHLDQVLVEKATVV 3064
++ K+E+ + K+L ++ +E +N+ + ++ K V
Sbjct: 536 RLARQEKEELHKQLVEASERLKSQTKELKDAHQQRKRALQEFSELNERMSELRSLKQKVS 595
Query: 3063 QQRDDMQAEL-----------ADVGDSLLTEKDSVKRLQDEAEKAKKQ------------ 2953
+Q D + E+ D+ S + K+ RL+D A +A K+
Sbjct: 596 RQLRDKEEEMEVAMQKIDSMRQDLRKSEKSRKELEARLEDAAAEASKERKLREHSESFCK 655
Query: 2952 --VADFXXXXXXXXXXXXXXXXKQEEVTIEARKSVETDDHLSEEVVAAKNTIASLQATNE 2779
+ + ++ + R +E EE + + L+ N
Sbjct: 656 QMERELEALKVKQGGRGPGAASEHQQEISKIRSELEKKVLFYEEELVRREASHVLEVKNV 715
Query: 2778 ERET------------EIKKLKQRMDEERASHTAQSEQEMKQLEAHYERAQKMLQDN--- 2644
++E E+ LK ++++ + ++ E+ + ++ YER + ML D
Sbjct: 716 KKEVHDSESHQLALQKEVLMLKDKLEKSKRERHSEMEEAIGTVKDKYERERAMLFDENKK 775
Query: 2643 -----------VEQMNVENRGLRDEIEKLSQQMAALPRGGLNEQQLHEIFNWVSEEKATR 2497
V+++ +NR L DE++ L+ + ++ E Q+ EI WVS+EK R
Sbjct: 776 LTAENEKLCSFVDKLTAQNRQLEDELQDLASKKESVAHW---EAQIAEIIQWVSDEKDAR 832
Query: 2496 EEMENLTRKITGEVESLKNNSPLTTSNYIQNTPSGWGSRRMNNVARKDGLDLQRQLQAEI 2317
++ L K+T E+E+L+++S + + W RR + L+LQ L+AEI
Sbjct: 833 GYLQALASKMTEELETLRSSSLGS-----RTLDPLWKVRRSQKLDMSARLELQSALEAEI 887
Query: 2316 DAKLKLKAELKNSQEQYLTSAARLDDTEKRMASLMREVAMLKQQKNIENSSDSAFSSTMG 2137
AK ++ EL+ ++ L ++L ++E + L+ E+ L+++ + +D+
Sbjct: 888 RAKQLVQEELRKVKDSSLAFESKLKESEAKNRELLEEMQSLRKRMEEKFRADTGLK---- 943
Query: 2136 RGDLMISMNNDYEMSNSSLMRQEMISRQSTPS-YENAILLHDHQVPKRVDDLRYKQKPMK 1960
L ++ +E N++ + ++ R S+ S E D V +Q+ M
Sbjct: 944 ---LPDFQDSIFEYFNTAPLAHDLTFRTSSASDQETQASKMDLSPSVSVATSTEQQEDMA 1000
Query: 1959 TASGIFSPVSISAME---------RGHNFERMKIKTPTKCGHCTSILIGLDRQGLFCQSC 1807
SPV + + + + H F +PT+C HCTS+++GL RQG C+ C
Sbjct: 1001 RPQQRPSPVPLPSTQALAMAGPKPKAHQFSIKSFPSPTQCSHCTSLMVGLIRQGYACEVC 1060
Query: 1806 QYACHVSCAERVSQSCPV-PEEERRPLGIDPTRGVGTAYEGLVKTPRAGGVRKGWQTAYV 1630
++CHVSC + Q CP+ PE+ +RPLG+D RG+GTAY+G VK P+ GV+KGWQ AY
Sbjct: 1061 AFSCHVSCKDSAPQVCPIPPEQSKRPLGVDVQRGIGTAYKGYVKVPKPTGVKKGWQRAYA 1120
Query: 1629 VVCDFKLYLYDCTVDRQNKMQDVKNEIRLVLDMRDPDFTVCGVSEADVIHAQKGDIPKIF 1450
VVCD KL+LYD + + V ++ VLD+RD +F V V +DVIHA + DIP IF
Sbjct: 1121 VVCDCKLFLYDLPEGKSTQPGVVASQ---VLDLRDEEFAVSSVLASDVIHATRRDIPCIF 1177
Query: 1449 RVTTTQILNXXXXXXXXSKFYTLFMAETEEEKRKWVVALSELKTLLRRSKLADRKAFLVK 1270
RVT + + + L + E E EKRKWV L L+ +L +++L + + +
Sbjct: 1178 RVTASLLGSPSKTSS------LLILTENENEKRKWVGILEGLQAILHKNRLKSQVVHVAQ 1231
Query: 1269 EVFDVTTLPSIRVAQCCAIIDRSKIVIGFSDHGLYCIEISRQLLIPVGGEKENKQRCVET 1090
E +D ++LP I+ AI+D +I +G + GLY IE++R +++ K+ V
Sbjct: 1232 EAYD-SSLPLIKAVLAAAIVDGDRIAVGL-EEGLYVIELTRDVIVRAADCKK-----VYQ 1284
Query: 1089 VEYDEAEQLLMMIVGPAKDRHVRIVPSAALDGRDLK--WIKVNDTKGCHLLAVGTNNPGG 916
+E E++ +++ G ++ HV + P ++ DG + IK+ +TKGC L+A GT
Sbjct: 1285 IELAPKEKIAILLCG--RNHHVHLYPWSSFDGAEASNFDIKLPETKGCQLIATGTLRKSS 1342
Query: 915 RAGFFAVAFKKSVTIFQIDRSEKRHKKWKDLAMPGTPQSIAIFNGRLYVGFSHSFRSWSL 736
F VA K+ + ++I R++ H+K+ +L PG Q +A+F RL VG+ F S+
Sbjct: 1343 STCLF-VAVKRLILCYEIQRTKPFHRKFSELVAPGHVQWMAVFKDRLCVGYPSGFSLLSI 1401
Query: 735 VGVDSSPVGSGDASGAVLQHISLVNMEDTSLQFLNQQTSYEAKLIVNVPGSPDEYLLVFN 556
G D P + LVN D SL FL+QQ S++A V + +EYLL F+
Sbjct: 1402 QG-DGPP-------------LDLVNPTDPSLAFLSQQ-SFDALCAVEL--KSEEYLLCFS 1444
Query: 555 MIGLYVNEMGRRSRLPEVMFPTQAKYFAYHEPYLCVFSENEVDIFNVTLAEWVQTINLRS 376
+GLYV+ GRRSR+ E+M+P + ++ V+SE VD+F+V EWVQTI LR
Sbjct: 1445 HMGLYVDPQGRRSRMQELMWPAAPVACSCSPTHVTVYSEYGVDVFDVRTMEWVQTIGLRR 1504
Query: 375 AKPLSGDGILSTCLCNDSPIFVLLQNVLQDQDSIEVPVNLASGSTDGXXXXXXXXXXXTI 196
+PL+ DG L+ C + P + +N + VP + +
Sbjct: 1505 IRPLNSDGSLNLLGC-EPPRLIYFKNKFSG-TILNVPDTSDNSKKQMLRTRSKRRFVFKV 1562
Query: 195 GKDDRSASERRSHIQ--------ISTPSDFMHIVHMGPAPVMEL 88
+++R +RR ++ IS P++F H+ HMGP M++
Sbjct: 1563 PEEER-LQQRREMLRDPELRSKMISNPTNFNHVAHMGPGDGMQV 1605
>gi|16758420|ref|NP_446072.1| Cdc42-binding protein kinase beta
[Rattus norvegicus]
gi|7446380|pir||T14050 protein kinase (EC 2.7.1.37) beta, myotonic
dystrophy-associated - rat
gi|2736153|gb|AAC02942.1| myotonic dystrophy kinase-related
Cdc42-binding kinase MRCK-beta [Rattus norvegicus]
Length = 1702
Score = 997 bits (2578), Expect = 0.0
Identities = 614/1660 (36%), Positives = 918/1660 (54%), Gaps = 104/1660 (6%)
Frame = -1
Query: 4755 SAPVRLKTLENIYMDGPSKKPEALSFETLIDSLICLYDECCNSTLRKEKCIAEFVESVKT 4576
SA VRLK LE + +DGP + +LS ETL+D L+CLY EC +S LR++K +AEF+E K
Sbjct: 2 SAKVRLKKLEQLLLDGPWRNESSLSVETLLDVLVCLYTECSHSALRRDKYVAEFLEWAKP 61
Query: 4575 VISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACF 4396
K ++L R+DFE++KVIG+GAFGEVAVV+M+ IYAMKILNKWEM+KRAETACF
Sbjct: 62 FTQLVKDMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACF 121
Query: 4395 REERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFYI 4216
REERDVLV GD +WIT LHYAFQDE LY VMDYY+GGD+LTLLSKF D +PE MA+FYI
Sbjct: 122 REERDVLVNGDCQWITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYI 181
Query: 4215 AEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASNVAVGTPD 4036
EMVLAIDS+H+L YVHRD+KPDNVLLD+ GHIRLADFGSCL++ DG+V S+VAVGTPD
Sbjct: 182 GEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPD 241
Query: 4035 YISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDMLD 3856
YISPEIL+AMEDG G+YG ECDWWSLG+CMYEMLYG TPFY+E LV+TYGKIM+H++
Sbjct: 242 YISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQ 301
Query: 3855 FPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIRDSNPPYVP 3676
FP D VSEEAKDLI++LICS + R G+NG+ DF+ H FFEG++W IR+ PY+P
Sbjct: 302 FPSHVTD--VSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIP 359
Query: 3675 EVSSPEDTSNFDVDVCEDDFTPCLQETQPPRVLAAFTGNHLPFVGFSYTHGSLLSDARSL 3496
+VSSP DTSNFDVD DD + E PP F+G HLPF+GF++T S SD SL
Sbjct: 360 DVSSPSDTSNFDVD---DDVLRNI-EILPPGSHTGFSGLHLPFIGFTFTTESCFSDRGSL 415
Query: 3495 TDEIRAIA----QRCQGDAE--LMEKSVDGFMVELENEKAELVQKLKEA-QTIIAQH--- 3346
I++ + Q D E L ++ + + LE EK EL +KL+E+ QT+ + H
Sbjct: 416 KSMIQSNTLTKDEDVQRDLENSLQIEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGST 475
Query: 3345 --VAENPRSEEDRNYESTIAQLKDEI---QILNKRLEDEALAQQQ--------------- 3226
+ + R +E + + ++K ++ L ++LED +Q+
Sbjct: 476 RALGNSNRDKEIKRLNEELERMKSKMADSNRLERQLEDTVTLRQEHEDSTQRLKGLEKQY 535
Query: 3225 ---QKPKDEIVAXXXXXXXXXXERNKQLV---MEKSEIQRELDNINDHLDQVLVEKATVV 3064
++ K+E+ + K+L ++ +E +N+ + ++ +K V
Sbjct: 536 RLARQEKEELHKQLVEASERLKSQTKELKDAHQQRKRALQEFSELNERMAELRSQKQKVS 595
Query: 3063 QQRDDMQAEL-----------ADVGDSLLTEKDSVKRLQD---EAEK-----------AK 2959
+Q D + E+ D+ S + K+ RL+D EA K +K
Sbjct: 596 RQLRDKEEEMEVAMQKIDSMRQDIRKSEKSRKELEARLEDAVAEASKERKLREHSESFSK 655
Query: 2958 KQVADFXXXXXXXXXXXXXXXXKQEEVTIEARKSVETDDHLSEEVVAAKNTIASLQATNE 2779
+ + + ++ + R +E EE + + L+ N
Sbjct: 656 QMERELETLKVKQGGRGPGATLEHQQEISKIRSELEKKVLFYEEELVRRERSHVLEVKNV 715
Query: 2778 ERET------------EIKKLKQRMDEERASHTAQSEQEMKQLEAHYERAQKMLQDN--- 2644
++E E+ LK ++++ + ++ E+ + ++ YER + ML D
Sbjct: 716 KKEVHESESHQLALQKEVLMLKDKLEKSKRERHSEMEEAIGAMKDKYERERAMLFDENKK 775
Query: 2643 -----------VEQMNVENRGLRDEIEKLSQQMAALPRGGLNEQQLHEIFNWVSEEKATR 2497
V+++ +NR L DE++ L+ + ++ E Q+ EI WVS+EK R
Sbjct: 776 LTAENEKLCSFVDKLTAQNRQLEDELQDLASKKESVAHW---EAQIAEIIQWVSDEKDAR 832
Query: 2496 EEMENLTRKITGEVESLKNNSPLTTSNYIQNTPSGWGSRRMNNVARKDGLDLQRQLQAEI 2317
++ L K+T E+E+L+++S + + W RR + L+LQ L+AEI
Sbjct: 833 GYLQALASKMTEELETLRSSSLGS-----RTLDPLWKVRRSQKLDMSARLELQSALEAEI 887
Query: 2316 DAKLKLKAELKNSQEQYLTSAARLDDTEKRMASLMREVAMLKQQKNIENSSDSAFSSTMG 2137
AK + EL+ ++ L ++L ++E + L+ E+ LK++ + +D+
Sbjct: 888 RAKQLVHEELRKVKDTSLAFESKLKESEAKNRELLEEMQSLKKRMEEKFRADTGLKLPDF 947
Query: 2136 RGDLMISMN-----NDYEMSNSSLMRQEMISRQSTPSYENAILLHDHQVPKRVDDLRYKQ 1972
+ + N +D SS QE + + S ++ Q + D R +Q
Sbjct: 948 QDPIFEYFNTAPLAHDLTFRTSSASDQETQASKLDLSPSVSVATSTEQ---QEDAARSQQ 1004
Query: 1971 KPMKTASGIFSPVSISAME-RGHNFERMKIKTPTKCGHCTSILIGLDRQGLFCQSCQYAC 1795
+P ++++ + + H F +PT+C HCTS+++GL RQG C+ C ++C
Sbjct: 1005 RPSTVPLPNTQALAMAGPKPKAHQFSIKSFPSPTQCSHCTSLMVGLIRQGYACEVCAFSC 1064
Query: 1794 HVSCAERVSQSCPV-PEEERRPLGIDPTRGVGTAYEGLVKTPRAGGVRKGWQTAYVVVCD 1618
HVSC + Q CP+ PE+ +RPLG+D RG+GTAY+G VK P+ GV+KGWQ AY VVCD
Sbjct: 1065 HVSCKDSAPQVCPIPPEQSKRPLGVDVQRGIGTAYKGYVKVPKPTGVKKGWQRAYAVVCD 1124
Query: 1617 FKLYLYDCTVDRQNKMQDVKNEIRLVLDMRDPDFTVCGVSEADVIHAQKGDIPKIFRVTT 1438
KL+LYD + + + ++ VLD+RD +F V V +DVIHA + DIP IFRVT
Sbjct: 1125 CKLFLYDLPEGKSTQPGVIASQ---VLDLRDDEFAVSSVLASDVIHATRRDIPCIFRVTA 1181
Query: 1437 TQILNXXXXXXXXSKFYTLFMAETEEEKRKWVVALSELKTLLRRSKLADRKAFLVKEVFD 1258
+ + + L + E E EKRKWV L L+ +L +++L + + +E +D
Sbjct: 1182 SLLGSPSKTSS------LLILTENENEKRKWVGILEGLQAILHKNRLRSQVVHVAQEAYD 1235
Query: 1257 VTTLPSIRVAQCCAIIDRSKIVIGFSDHGLYCIEISRQLLIPVGGEKENKQRCVETVEYD 1078
++LP I+ AI+D +I +G + GLY IE++R +++ K+ V +E
Sbjct: 1236 -SSLPLIKTVLAAAIVDGDRIAVGL-EEGLYVIELTRDVIVRAADCKK-----VYQIELA 1288
Query: 1077 EAEQLLMMIVGPAKDRHVRIVPSAALDGRDLK--WIKVNDTKGCHLLAVGTNNPGGRAGF 904
E+L++++ G ++ HV + P + DG + IK+ +TKGC L+A GT
Sbjct: 1289 PKEKLILLLCG--RNHHVHLYPWTSFDGAEASNFDIKLPETKGCQLIATGTLRKSSSTCL 1346
Query: 903 FAVAFKKSVTIFQIDRSEKRHKKWKDLAMPGTPQSIAIFNGRLYVGFSHSFRSWSLVGVD 724
F VA K+ V ++I R++ H+K+ ++ PG Q +A+F RL VG+ F S+ G D
Sbjct: 1347 F-VAVKRLVLCYEIQRTKPFHRKFNEIVAPGHVQWMAMFKDRLCVGYPSGFSLLSIQG-D 1404
Query: 723 SSPVGSGDASGAVLQHISLVNMEDTSLQFLNQQTSYEAKLIVNVPGSPDEYLLVFNMIGL 544
P + LVN D SL FL+QQ S++A V + +EYLL F+ +GL
Sbjct: 1405 GQP-------------LDLVNPADPSLAFLSQQ-SFDALCAVEL--KSEEYLLCFSHMGL 1448
Query: 543 YVNEMGRRSRLPEVMFPTQAKYFAYHEPYLCVFSENEVDIFNVTLAEWVQTINLRSAKPL 364
YV+ GRRSR E+M+P + ++ V+SE VD+F+V EWVQTI LR +PL
Sbjct: 1449 YVDPQGRRSRTQELMWPAAPVACSCSSSHVTVYSEYGVDVFDVRTMEWVQTIGLRRIRPL 1508
Query: 363 SGDGILSTCLCNDSPIFVLLQNVLQDQDSIEVPVNLASGSTDGXXXXXXXXXXXTIGKDD 184
+ DG L+ C + P + +N + VP + + +++
Sbjct: 1509 NSDGSLNLLGC-EPPCLIYFKNKFSG-TVLNVPDTSDNSKKQMLRTRSKRRFVFKVPEEE 1566
Query: 183 RSASERRSHIQ--------ISTPSDFMHIVHMGPAPVMEL 88
R +RR ++ IS P++F H+ HMGP M++
Sbjct: 1567 R-LQQRREMLRDPELRSKMISNPTNFNHVAHMGPGDGMQV 1605
>gi|30841498|gb|AAP34403.1| CDC42-binding protein kinase beta [Rattus
norvegicus]
Length = 1713
Score = 997 bits (2578), Expect = 0.0
Identities = 617/1678 (36%), Positives = 927/1678 (54%), Gaps = 104/1678 (6%)
Frame = -1
Query: 4755 SAPVRLKTLENIYMDGPSKKPEALSFETLIDSLICLYDECCNSTLRKEKCIAEFVESVKT 4576
SA VRLK LE + +DGP + +LS ETL+D L+CLY EC +S LR++K +AEF+E K
Sbjct: 2 SAKVRLKKLEQLLLDGPWRNESSLSVETLLDVLVCLYTECSHSALRRDKYVAEFLEWAKP 61
Query: 4575 VISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACF 4396
K ++L R+DFE++KVIG+GAFGEVAVV+M+ IYAMKILNKWEM+KRAETACF
Sbjct: 62 FTQLVKDMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACF 121
Query: 4395 REERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFYI 4216
REERDVLV GD +WIT LHYAFQDE LY VMDYY+GGD+LTLLSKF D +PE MA+FYI
Sbjct: 122 REERDVLVNGDCQWITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYI 181
Query: 4215 AEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASNVAVGTPD 4036
EMVLAIDS+H+L YVHRD+KPDNVLLD+ GHIRLADFGSCL++ DG+V S+VAVGTPD
Sbjct: 182 GEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPD 241
Query: 4035 YISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDMLD 3856
YISPEIL+AMEDG G+YG ECDWWSLG+CMYEMLYG TPFY+E LV+TYGKIM+H++
Sbjct: 242 YISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQ 301
Query: 3855 FPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIRDSNPPYVP 3676
FP D VSEEAKDLI++LICS + R G+NG+ DF+ H FFEG++W IR+ PY+P
Sbjct: 302 FPSHVTD--VSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIP 359
Query: 3675 EVSSPEDTSNFDVDVCEDDFTPCLQETQPPRVLAAFTGNHLPFVGFSYTHGSLLSDARSL 3496
+VSSP DTSNFDVD DD + E PP F+G HLPF+GF++T S SD SL
Sbjct: 360 DVSSPSDTSNFDVD---DDVLRNI-EILPPGSHTGFSGLHLPFIGFTFTTESCFSDRGSL 415
Query: 3495 TDEIRAIA----QRCQGDAE--LMEKSVDGFMVELENEKAELVQKLKEA-QTIIAQH--- 3346
I++ + Q D E L ++ + + LE EK EL +KL+E+ QT+ + H
Sbjct: 416 KSMIQSNTLTKDEDVQRDLENSLQIEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGST 475
Query: 3345 --VAENPRSEEDRNYESTIAQLKDEI---QILNKRLEDEALAQQQ--------------- 3226
+ + R +E + + ++K ++ L ++LED +Q+
Sbjct: 476 RALGNSNRDKEIKRLNEELERMKSKMADSNRLERQLEDTVTLRQEHEDSTQRLKGLEKQY 535
Query: 3225 ---QKPKDEIVAXXXXXXXXXXERNKQLV---MEKSEIQRELDNINDHLDQVLVEKATVV 3064
++ K+E+ + K+L ++ +E +N+ + ++ +K V
Sbjct: 536 RLARQEKEELHKQLVEASERLKSQTKELKDAHQQRKRALQEFSELNERMAELRSQKQKVS 595
Query: 3063 QQRDDMQAEL-----------ADVGDSLLTEKDSVKRLQD---EAEK-----------AK 2959
+Q D + E+ D+ S + K+ RL+D EA K +K
Sbjct: 596 RQLRDKEEEMEVAMQKIDSMRQDIRKSEKSRKELEARLEDAVAEASKERKLREHSESFSK 655
Query: 2958 KQVADFXXXXXXXXXXXXXXXXKQEEVTIEARKSVETDDHLSEEVVAAKNTIASLQATNE 2779
+ + + ++ + R +E EE + + L+ N
Sbjct: 656 QMERELETLKVKQGGRGPGATLEHQQEISKIRSELEKKVLFYEEELVRREASHVLEVKNV 715
Query: 2778 ERET------------EIKKLKQRMDEERASHTAQSEQEMKQLEAHYERAQKMLQDN--- 2644
++E E+ LK ++++ + ++ E+ + ++ YER + ML D
Sbjct: 716 KKEVHESESHQLALQKEVLMLKDKLEKSKRERHSEMEEAIGAMKDKYERERAMLFDENKK 775
Query: 2643 -----------VEQMNVENRGLRDEIEKLSQQMAALPRGGLNEQQLHEIFNWVSEEKATR 2497
V+++ +NR L DE++ L+ + ++ E Q+ EI WVS+EK R
Sbjct: 776 LTAENEKLCSFVDKLTAQNRQLEDELQDLASKKESVAHW---EAQIAEIIQWVSDEKDAR 832
Query: 2496 EEMENLTRKITGEVESLKNNSPLTTSNYIQNTPSGWGSRRMNNVARKDGLDLQRQLQAEI 2317
++ L K+T E+E+L+++S + + W RR + L+LQ L+AEI
Sbjct: 833 GYLQALASKMTEELETLRSSSLGS-----RTLDPLWKVRRSQKLDMSARLELQSALEAEI 887
Query: 2316 DAKLKLKAELKNSQEQYLTSAARLDDTEKRMASLMREVAMLKQQKNIENSSDSAFSSTMG 2137
AK + EL+ ++ L ++L ++E + L+ E+ LK++ + +D+
Sbjct: 888 RAKQLVHEELRKVKDTSLAFESKLKESEAKNRELLEEMQSLKKRMEEKFRADTGLKLPDF 947
Query: 2136 RGDLMISMN-----NDYEMSNSSLMRQEMISRQSTPSYENAILLHDHQVPKRVDDLRYKQ 1972
+ + N +D SS QE + + S ++ Q + D R +Q
Sbjct: 948 QDPIFEYFNTAPLAHDLTFRTSSASDQETQASKLDLSPSVSVATSTEQ---QEDAARSQQ 1004
Query: 1971 KPMKTASGIFSPVSISAME-RGHNFERMKIKTPTKCGHCTSILIGLDRQGLFCQSCQYAC 1795
+P ++++ + + H F +PT+C HCTS+++GL RQG C+ C ++C
Sbjct: 1005 RPSTVPLPNTQALAMAGPKPKAHQFSIKSFPSPTQCSHCTSLMVGLIRQGYACEVCAFSC 1064
Query: 1794 HVSCAERVSQSCPV-PEEERRPLGIDPTRGVGTAYEGLVKTPRAGGVRKGWQTAYVVVCD 1618
HVSC + Q CP+ PE+ +RPLG+D RG+GTAY+G VK P+ GV+KGWQ AY VVCD
Sbjct: 1065 HVSCKDSAPQVCPIPPEQSKRPLGVDVQRGIGTAYKGYVKVPKPTGVKKGWQRAYAVVCD 1124
Query: 1617 FKLYLYDCTVDRQNKMQDVKNEIRLVLDMRDPDFTVCGVSEADVIHAQKGDIPKIFRVTT 1438
KL+LYD + + + ++ VLD+RD +F V V +DVIHA + DIP IFRVT
Sbjct: 1125 CKLFLYDLPEGKSTQPGVIASQ---VLDLRDDEFAVSSVLASDVIHATRRDIPCIFRVTA 1181
Query: 1437 TQILNXXXXXXXXSKFYTLFMAETEEEKRKWVVALSELKTLLRRSKLADRKAFLVKEVFD 1258
+ + + L + E E EKRKWV L L+ +L +++L + + +E +D
Sbjct: 1182 SLLGSPSKTSS------LLILTENENEKRKWVGILEGLQAILHKNRLRSQVVHVAQEAYD 1235
Query: 1257 VTTLPSIRVAQCCAIIDRSKIVIGFSDHGLYCIEISRQLLIPVGGEKENKQRCVETVEYD 1078
++LP I+ AI+D +I +G + GLY IE++R +++ K+ V +E
Sbjct: 1236 -SSLPLIKTVLAAAIVDGDRIAVGL-EEGLYVIELTRDVIVRAADCKK-----VYQIELA 1288
Query: 1077 EAEQLLMMIVGPAKDRHVRIVPSAALDGRDLK--WIKVNDTKGCHLLAVGTNNPGGRAGF 904
E+L++++ G ++ HV + P + DG + IK+ +TKGC L+A GT
Sbjct: 1289 PKEKLILLLCG--RNHHVHLYPWTSFDGAEASNFDIKLPETKGCQLIATGTLRKSSSTCL 1346
Query: 903 FAVAFKKSVTIFQIDRSEKRHKKWKDLAMPGTPQSIAIFNGRLYVGFSHSFRSWSLVGVD 724
F VA K+ V ++I R++ H+K+ ++ PG Q +A+F RL VG+ F S+ G D
Sbjct: 1347 F-VAVKRLVLCYEIQRTKPFHRKFNEIVAPGHVQWMAMFKDRLCVGYPSGFSLLSIQG-D 1404
Query: 723 SSPVGSGDASGAVLQHISLVNMEDTSLQFLNQQTSYEAKLIVNVPGSPDEYLLVFNMIGL 544
P + LVN D SL FL+QQ S++A V + +EYLL F+ +GL
Sbjct: 1405 GQP-------------LDLVNPADPSLAFLSQQ-SFDALCAVEL--KSEEYLLCFSHMGL 1448
Query: 543 YVNEMGRRSRLPEVMFPTQAKYFAYHEPYLCVFSENEVDIFNVTLAEWVQTINLRSAKPL 364
YV+ GRRSR E+M+P + ++ V+SE VD+F+V EWVQTI LR +PL
Sbjct: 1449 YVDPQGRRSRTQELMWPAAPVACSCSSSHVTVYSEYGVDVFDVRTMEWVQTIGLRRIRPL 1508
Query: 363 SGDGILSTCLCNDSPIFVLLQNVLQDQDSIEVPVNLASGSTDGXXXXXXXXXXXTIGKDD 184
+ DG L+ C + P + +N + VP + + +++
Sbjct: 1509 NSDGSLNLLGC-EPPRLIYFKNKFSG-TVLNVPDTSDNSKKQMLRTRSKRRFVFKVPEEE 1566
Query: 183 RSASERRSHIQ--------ISTPSDFMHIVHMGPAPVMELQQNFIDLQSNHSHTSSDK 34
R +RR ++ IS P++F H+ HMGP M++ +DL + + T+ ++
Sbjct: 1567 R-LQQRREMLRDPELRSKMISNPTNFNHVAHMGPGDGMQV---LMDLPLSAAPTAQEE 1620
>gi|47222704|emb|CAG00138.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 1949
Score = 972 bits (2512), Expect(2) = 0.0
Identities = 622/1637 (37%), Positives = 901/1637 (54%), Gaps = 139/1637 (8%)
Frame = -1
Query: 4581 KTVISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETA 4402
K SK K++RL ++DFE+LKVIG+GAFGEVAVV++R +++AMKILNKWEM+KRAETA
Sbjct: 189 KPFTSKVKQMRLHKEDFEILKVIGRGAFGEVAVVKVRNTDKVFAMKILNKWEMLKRAETA 248
Query: 4401 CFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKF 4222
CFREERDVLV GD +WIT LHYAFQDE NLY VMDYY+GGD+LTLLSKF D +PE MAKF
Sbjct: 249 CFREERDVLVNGDCQWITTLHYAFQDENNLYLVMDYYVGGDLLTLLSKFEDRLPEEMAKF 308
Query: 4221 YIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASNVAVGT 4042
Y+AEMVLAIDS+H+L YVHRD+KPDN+LLD+ GHIRLADFGSCLR++ DG+V S+VAVGT
Sbjct: 309 YLAEMVLAIDSVHQLHYVHRDIKPDNILLDVNGHIRLADFGSCLRLMEDGTVQSSVAVGT 368
Query: 4041 PDYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDM 3862
PDYISPEIL+AMEDG+G+YG ECDWWSLG+CMYEMLYG TPFY+E LV+TYGKIM+H++
Sbjct: 369 PDYISPEILQAMEDGKGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER 428
Query: 3861 LDFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEG-IDWNTIRDSNPP 3685
FP D VSEEAKDLIR+LICS + R G+NG+ DF+ HPFF G IDW I P
Sbjct: 429 FQFPQQVTD--VSEEAKDLIRRLICSREHRLGQNGIEDFKHHPFFTGSIDWENILTCEAP 486
Query: 3684 YVPEVSSPEDTSNFDVDVCEDDFTPCLQ--ETQPPRVLAAFTGNHLPFVGFSYTHGSLLS 3511
Y+PEVSSP DTSNFDVD DD CL+ ET PP AF+G HLPFVGF+YT LS
Sbjct: 487 YIPEVSSPTDTSNFDVD---DD---CLKNSETMPPPSHTAFSGLHLPFVGFTYTSKCTLS 540
Query: 3510 D-----------ARSLTDEIRAIAQRCQGDAELMEKSVDGFMVELENEKAELVQKLKEA- 3367
D R+ D++ QR D+ L ++ + + LE EK EL +KL+E+
Sbjct: 541 DQGCLRQLAVDPGRAGKDQLDLDVQRGLEDS-LATEAYERRIRRLEQEKLELTRKLQEST 599
Query: 3366 QTIIA-QH-VAENPRSEEDRNYESTIAQLKDEIQILNKRLEDEALAQQQQKPKDEIVAXX 3193
QT+ A QH E P S N E I LK EI +L K++ D Q +++ +D +A
Sbjct: 600 QTVQALQHQTGEGPLS---TNREVEIRSLKSEIDVLKKQIADS--GQLEKQLEDVSLARR 654
Query: 3192 XXXXXXXXERN-----KQLVMEKSEIQRELDNINDHLDQVLVEKATVVQQRDDMQAELAD 3028
++ K L E+ E+ +++ + L E QR E ++
Sbjct: 655 DLEDSSRHVKSLEKQMKSLTQERDELHKDVLEATEKLRSQSKELKEAHSQRKLAMQEFSE 714
Query: 3027 VGDSLLTEKDSVKRL-------QDEAEKAKKQVADFXXXXXXXXXXXXXXXXKQEE---V 2878
+ + L + + +RL ++E E ++V + EE
Sbjct: 715 LNERLTDLRSAKQRLTRQLRDKEEEMESQTQRVEALRLEVRKAERAKKEMESQAEEQSAE 774
Query: 2877 TIEARKSVETDD----HLSEEVVAAKNTIASLQATNEERET------------------- 2767
T++ RK E ++ L EE+ K T + ++ ++
Sbjct: 775 TLKERKMRERNEQYSRQLEEELERLKVTADGMSRADQAKQAGPSAAPSSVDQTQEVGRLR 834
Query: 2766 -EIKKLKQRMDEERASHTAQSEQEMKQL-------EAHYERAQK---MLQDNVEQMNVEN 2620
+++K +EE A AQ E+K L E+ + QK ML+D +E+ E+
Sbjct: 835 GDLEKKTLLYEEELARREAQHSTELKALRKDLRDAESQHLALQKEVLMLKDKLEKTRRES 894
Query: 2619 RGLRDEIE-------------------KLSQQMAAL----PRGGLNEQQLHE-------- 2533
+ R+E E KLS ++ L + + +QL +
Sbjct: 895 QSEREEFEADYKEKYERERSLLTEENKKLSSELEKLTGMFEKVSSSNRQLEDEMRELADK 954
Query: 2532 ---IFNW----------VSEEKATREEMENLTRKITGEVESLKNNSPLTTSNYIQNTPSG 2392
+ +W VS+EK R ++ L K+T E+E L+N TS + T
Sbjct: 955 KESVAHWEAQITEIIQWVSDEKDARGYLQALATKMTEELEGLRN-----TSLGARATDMP 1009
Query: 2391 WGSRRMNNVARKDGLDLQRQLQAEIDAKLKLKAELKNSQEQYLTSAARLDDTEKRMASLM 2212
W RR + L+LQ L AEI AK ++ EL + + + +L DTE + L+
Sbjct: 1010 WKMRRFAKLDMSARLELQSALDAEIRAKQSIQDELNKVKAGNIATECKLQDTESKNQELL 1069
Query: 2211 REVAMLKQQKN--------IENSSDSAF-----SSTMGRGDLMISMNNDYEMSNSSLM-- 2077
E+ LK++ S ++F + T + ++ SN+
Sbjct: 1070 AEIDRLKKEMEELRLRRGVKHQDSQNSFLAFLNAPTSALDQFDVDSIENFTPSNTPSRED 1129
Query: 2076 --RQEMISRQSTPSYEN---AILLHDHQVPKRVDDLRYKQKPMKTASGIFSPVSISAMER 1912
+ + SR +PS + + L DH R Q P + G S S +
Sbjct: 1130 DPKSHLKSRSRSPSMASDMEPVELMDHPA-------RPAQTPTLRSGGYGSIGRSSPKSK 1182
Query: 1911 GHNFERMKIKTPTKCGHCTSILIGLDRQGLFCQSCQYACHVSCAERVSQSCPVPEEERR- 1735
H F TPTKC CTS+++GL RQG C+ C ++CHV+CA++ CPVP ++ +
Sbjct: 1183 AHQFVVKTFNTPTKCNRCTSLMVGLIRQGCTCEVCNFSCHVTCADKAPAVCPVPPDQTKG 1242
Query: 1734 PLGIDPTRGVGTAYEGLVKTPRAGGVRKGWQTAYVVVCDFKLYLYDCTVDRQNKMQDVKN 1555
PLGIDP RG+GT YEG V+ P+ GV+KGWQ A VVCDFKL+LY+ + + V +
Sbjct: 1243 PLGIDPQRGIGTVYEGHVRVPKPTGVKKGWQRAMAVVCDFKLFLYELGEGKATQPSVVVS 1302
Query: 1554 EIRLVLDMRDPDFTVCGVSEADVIHAQKGDIPKIFRVTTTQILNXXXXXXXXSKFYTLFM 1375
+ V+DMRD +F+V V ++DVIHA + DIP IFRVT +Q+ K L +
Sbjct: 1303 Q---VIDMRDEEFSVSSVLDSDVIHASRKDIPCIFRVTASQL-----SPSSSHKPSVLIL 1354
Query: 1374 AETEEEKRKWVVALSELKTLLRRSKLADRKAFLVKEVFDVTTLPSIRVAQCCAIIDRSKI 1195
A++++E+ KWV L+EL +LR++KL +R ++ KE +D +TLP I+ Q AIID ++
Sbjct: 1355 ADSDQERNKWVGLLNELHRILRKNKLKERFVYVPKEAYD-STLPLIKSTQSAAIIDHERV 1413
Query: 1194 VIGFSDHGLYCIEISRQLLIPVGGEKENKQRCVETVEYDEAEQLLMMIVGPAKDRHVRIV 1015
+G ++ GL+ + +++ +I VG K+ V ++ EQLL ++ G ++RHVR+
Sbjct: 1414 ALG-NEEGLFVVHVTKDEIIRVGDNKK-----VHHIDLMLQEQLLAVVSG--RNRHVRLF 1465
Query: 1014 PSAALDGRDLKWIKVNDTKGCHLLAVGTNNPGGRAGFFAVAFKKSVTIFQIDRSEKRHKK 835
+ ALDGR+ + K+ +TKGC +A G GG VA K+ + +++++ + RH++
Sbjct: 1466 LTQALDGRESESFKLAETKGCQSVASGQVR-GGALTCLCVAMKRQIICYEVNKGKARHRR 1524
Query: 834 WKDLAMPGTPQSIAIFNGRLYVGFSHSFRSWSLVGVDSSPVGSGDASGAVLQHISLVNME 655
++L P + Q +A+ + RLYVG+ F +S+ G D++PV SL++ E
Sbjct: 1525 LRELQAPASVQWMALLSERLYVGYQSGFTRYSVHG-DAAPV-------------SLLHPE 1570
Query: 654 DTSLQFLNQQTSYEAKLIVNVPGSPDEYLLVFNMIGLYVNEMGRRSRLPEVMFPTQAKYF 475
D +L F+ QQ S +A V + S E LL F+ IG+YV+ GRRSR E+M+P
Sbjct: 1571 DHTLAFIPQQ-SLDALCAVEI--SSKELLLCFSAIGVYVDSQGRRSRQQELMWPAVPNAA 1627
Query: 474 AYHEPYLCVFSENEVDIFNVTLAEWVQTINLRSAKPLSGDGILSTCLCNDSPIFVLLQNV 295
Y+ PYL V+SEN VD+F+V EW+QTI L+ +PL+ DG L+ L ++ V +N
Sbjct: 1628 CYNAPYLSVYSENAVDVFDVNNMEWIQTIPLKKVRPLNVDGSLN-LLGLETVRLVYFRNK 1686
Query: 294 LQDQDSIEVPVNLASGSTDGXXXXXXXXXXXTIGKDDRSASERRSHIQ--------ISTP 139
+ + D + VP + ++ +RR ++ IS P
Sbjct: 1687 MAEGDELVVPETSDNSRKQMVRSLNNKRRFSFRVPEEERLQQRREMLRDPEMRNKLISNP 1746
Query: 138 SDFMHIVHMGPAPVMEL 88
++F H+ HMGP +++
Sbjct: 1747 TNFNHVAHMGPGDGIQI 1763
Score = 63.2 bits (152), Expect = 6e-08
Identities = 32/63 (50%), Positives = 44/63 (69%), Gaps = 1/63 (1%)
Frame = -1
Query: 4755 SAPVRLKTLENIYMDGPS-KKPEALSFETLIDSLICLYDECCNSTLRKEKCIAEFVESVK 4579
S VRLK LE + +DGP+ + LS E+L+D L+CLYDEC NS LR+EK I EF++ K
Sbjct: 2 SGEVRLKKLEKLVLDGPAASNGQCLSVESLLDVLVCLYDECNNSPLRREKNILEFLDWGK 61
Query: 4578 TVI 4570
++
Sbjct: 62 LLL 64
Score = 22.7 bits (47), Expect(2) = 0.0
Identities = 10/31 (32%), Positives = 13/31 (41%)
Frame = -2
Query: 4778 WLNHRPMIRRRFASKPLKIFIWMARAKNPRH 4686
WLN RP A ++ F A +P H
Sbjct: 145 WLNSRPQTEEMLALPAIEGFCLALEAVDPTH 175
>gi|24762562|ref|NP_523837.2| CG4012-PA [Drosophila melanogaster]
gi|7291742|gb|AAF47163.1| CG4012-PA [Drosophila melanogaster]
gi|15291707|gb|AAK93122.1| LD24220p [Drosophila melanogaster]
Length = 1637
Score = 940 bits (2429), Expect = 0.0
Identities = 591/1609 (36%), Positives = 887/1609 (54%), Gaps = 61/1609 (3%)
Frame = -1
Query: 4710 GPSKKPEALSFETLIDSLICLYDECCNSTLRKEKCIAEFVESVKTVISKAKKLRLSRDDF 4531
G + S + L+D+ I LYDEC NS+LR+EK +++F++ K + +KLRLSRDDF
Sbjct: 41 GEDTEGHQFSLDYLLDTFIVLYDECSNSSLRREKGVSDFLKLSKPFVHIVRKLRLSRDDF 100
Query: 4530 EVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACFREERDVLVYGDRRWI 4351
++LK+IG+GAFGEV VV+M ++YAMKILNKWEM+KRAETACFREERDVLV+GDR+WI
Sbjct: 101 DILKIIGRGAFGEVCVVQMISTEKVYAMKILNKWEMLKRAETACFREERDVLVFGDRQWI 160
Query: 4350 TNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFYIAEMVLAIDSLHRLGY 4171
TNLHYAFQD NLY VMDYY GGD+LTLLSKF D +PE MAKFYI EM+LAI+S+H++ Y
Sbjct: 161 TNLHYAFQDNINLYLVMDYYCGGDLLTLLSKFEDKLPEDMAKFYITEMILAINSIHQIRY 220
Query: 4170 VHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASNVAVGTPDYISPEILRAMEDGRG 3991
VHRD+KPDNVLLD +GH+RLADFGSCLR+ DG+V SNVAVGTPDYISPEILRAMEDG+G
Sbjct: 221 VHRDIKPDNVLLDKRGHVRLADFGSCLRLDKDGTVQSNVAVGTPDYISPEILRAMEDGKG 280
Query: 3990 RYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDMLDFPDDE-IDWVVSEEA 3814
RYG ECDWWSLG+CMYEMLYG TPFY+E LV+TYGKIM+HQ+ + P E +++ VSE +
Sbjct: 281 RYGTECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHQNCFNLPSQETLNYKVSETS 340
Query: 3813 KDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIRDSNPPYVPEVSSPEDTSNFDVD 3634
+DL+ +LIC + R G+NG+ DF HP+F GIDW IR PYVPEVSSP DTSNFDV
Sbjct: 341 QDLLCKLICIPENRLGQNGIQDFMDHPWFVGIDWKNIRQGPAPYVPEVSSPTDTSNFDV- 399
Query: 3633 VCEDDFTPCLQETQPPRVLAAFTGNHLPFVGFSY--THGSLLSDARSLTDEIRAIAQRCQ 3460
DD L ++ PP AF+G HLPF+GF++ T S L ++ +
Sbjct: 400 ---DDNDVRLTDSIPPSANPAFSGFHLPFIGFTFSLTSSSTLDSKKNQSSGF-------- 448
Query: 3459 GDAELMEKSVDGFMVELENEKAELVQKLKEAQTIIAQHVAENPRSEEDRNYESTIAQLKD 3280
GD L S + N V ++ + ++E + + +LK
Sbjct: 449 GDDTLDTISSPQLAILPSNNSETPVDSVQLKALNDQLAALKQEKAELSKQHNEVFERLKT 508
Query: 3279 EIQILNKRLEDEALAQQQQKPKDEIVAXXXXXXXXXXERNKQLVMEKSEIQRELDNINDH 3100
+ L + +A + E + +L +K ++ R++ + +
Sbjct: 509 QDSELQDAISQRNIAMMEYSEVTE--------------KLSELRNQKQKLSRQVRDKEEE 554
Query: 3099 LDQVLVEKATV---VQQRDDMQAELADVGDSLLTEKDSVKRLQDEAEKAKKQVADFXXXX 2929
LD + + ++ +++ D + EL + + E K+L++ AE +Q+
Sbjct: 555 LDGAMQKNDSLRNELRKSDKTRRELELHIEDAVIEAAKEKKLREHAEDCCRQLQMELRKG 614
Query: 2928 XXXXXXXXXXXXKQEEVTIE-ARKSVETDDHLSE-------EVVAAKNTIASLQATNEER 2773
E + E R ++ + LS E+ A + + L+ N
Sbjct: 615 SSSVETTMPLSISSEMSSYEIERLELQFSEKLSHQQTRHNMELEALREQFSELENANLAL 674
Query: 2772 ETEIKKLKQRMDEERASHTAQSEQEMKQLEAHYERAQKMLQDNVE----QMNVENRGLR- 2608
E+++ ++R+ + S + + +L+ ++ + + + ++N++++ L+
Sbjct: 675 TKELQQTQERLKYTQMESITDSAETLLELKKQHDLEKSSWFEEKQRLSSEVNLKSKSLKE 734
Query: 2607 -----DEI-EKLSQQMAALPRGGLNEQQLHEIFNWVSEEKATREEMENLTRKITGEVESL 2446
DEI ++L + A+ L E+Q+ EI WVS+EK R ++ L K+T E+E L
Sbjct: 735 LQAEDDEIFKELRMKREAIT---LWERQMAEIIQWVSDEKDARGYLQALATKMTEELEYL 791
Query: 2445 KNNSPLTTSNYIQNTPSGWGSRRMNNVARKDGLDLQRQLQAEIDAKLKLKAELKNSQEQY 2266
K+ +N + N W +RR + + + L+LQ LQ EI AK + EL ++
Sbjct: 792 KHVGTF-NNNGVDN--KNWRNRRSQKLDKMELLNLQSALQREIQAKNMISDELSQTRSDL 848
Query: 2265 LTSAARLDDTEKRMASLM-----REVAMLKQQKNIENSSDSAFSSTMGRGDLMISMNNDY 2101
+++ + D +KR S++ +E + QK S+S + + G L + D
Sbjct: 849 ISTQKEVRDYKKRYDSILHDFQKKETELRDLQKGGLEYSESFLNKSTHHG-LSSAFFRDM 907
Query: 2100 EMSNSSLMRQEMISRQS----TPSY---ENAILLHDHQVPKRVDDLRYKQKPMKTASGI- 1945
++ + E +S TP++ N+ +L +++ PK MK AS
Sbjct: 908 SKNSEIIDSAESFGNESGDNFTPNFFQSGNSGMLFNYE-PKYAGKNNKDHSSMKEASVSD 966
Query: 1944 -----------FSPVSISAMERGHNFERMKIKTPTKCGHCTSILIGLDRQGLFCQSCQYA 1798
S + H F +PTKC HCTS+++GL RQG+ C+ C +A
Sbjct: 967 LSREESDQLVKESQKKVPGNTAIHQFLVRTFSSPTKCNHCTSLMVGLTRQGVVCEICGFA 1026
Query: 1797 CHVSCAERVSQSCPVP-EEERRPLGIDPTRGVGTAYEGLVKTPRAGGVRKGWQTAYVVVC 1621
CH C ++V +CPVP ++ +RPLGIDPTRG+GTAYEG VK P++G +++GW +VVVC
Sbjct: 1027 CHTICCQKVPTTCPVPMDQTKRPLGIDPTRGIGTAYEGYVKVPKSGVIKRGWIRQFVVVC 1086
Query: 1620 DFKLYLYDCTVDRQNKMQDVKNEIRLVLDMRDPDFTVCGVSEADVIHAQKGDIPKIFRVT 1441
DFKL+LYD + DR + V + VLDMRDP+F+V V E+DVIHA K D+P IF++
Sbjct: 1087 DFKLFLYDISPDR-CALPSV--SVSQVLDMRDPEFSVGSVRESDVIHAAKKDVPCIFKIK 1143
Query: 1440 TTQILNXXXXXXXXSKFYTLFMAETEEEKRKWVVALSELKTLLRRSKLADRKAFLVKEVF 1261
T I TL +A+ E EK KWV+AL EL +L+R+ L + F V E+
Sbjct: 1144 TALI-------DGGLSLNTLMLADNESEKSKWVIALGELHRILKRNSLPNTAIFKVNEIL 1196
Query: 1260 DVTTLPSIRVAQCCAIIDRSKIVIGFSDHGLYCIEISRQLLIPVGGEKENKQRCVETVEY 1081
D TL IR A C II ++I++G D GL+ I + + + +G K+ Q + Y
Sbjct: 1197 D-NTLSLIRNALCSVIIYPNQILLGTED-GLFYINLDQYEIARIGESKKILQ-----LWY 1249
Query: 1080 DEAEQLLMMIVGPAKDRHVRIVPSAALDGRDLKWIKVNDTKGCHLLAVGTNNPGGRAGF- 904
E EQ+L+++ G K R++R++P AL+ D++WIKV ++K C G +
Sbjct: 1250 IEEEQILVILCG--KQRNLRLLPIRALEASDVEWIKVVESKNCISACTGIIRRFPNIVYS 1307
Query: 903 FAVAFKK-----SVTIFQIDRSEKRHKKWKDLAMPGTPQSIAIFNG-RLYVGFSHSFRSW 742
F +A K+ + +++I+R+ RH+K + + Q + I + RL V F ++
Sbjct: 1308 FIIALKRPNNHTQIVVYEINRTRTRHQKTCEFTIGYMAQHLQILSDMRLVVAHQSGFTAY 1367
Query: 741 SLVGVDSSPVGSGDASGAVLQHISLVNMEDTSLQFLNQQTSYEAKLIVNV----PGSPDE 574
L G ++ +SLV+ E+ FLN + +A ++ + G+ E
Sbjct: 1368 FLRGEATA--------------MSLVHPENQLCAFLN-YSGVDAVRVIEILCPSGGNFGE 1412
Query: 573 YLLVFNMIGLYVNEMGRRSRLPEVMFPTQAKYFAYHEPYLCVFSENEVDIFNVTLAEWVQ 394
YLLVF + +YV+ GR+SR E+M+P Y + + +L VFS+ +DIFN AEWVQ
Sbjct: 1413 YLLVFQTLAIYVDLQGRKSRDREIMYPAFPTYITFCDGHLLVFSDTHLDIFNTQTAEWVQ 1472
Query: 393 TINLRSAKPLSGDGILSTCLCNDSPIFVLLQNVLQDQDSIEVPVNLASGSTDGXXXXXXX 214
+I L+ + PL+ G + ND+P+ V L N+ + + G+ G
Sbjct: 1473 SIGLKQSLPLNNLGNVVLSSVNDTPLIVYLSNI-----HTKGLLQYRDGNRKGLPSIKRR 1527
Query: 213 XXXXTIGKDDRSASERRSHIQISTPSDFMHIVHMGPAPVMELQQNFIDL 67
I K + S+RRS + IS P++F HI HMGP ++ Q +DL
Sbjct: 1528 FSIREINKTIK--SDRRSKM-ISAPTNFNHISHMGPGDGIQ-NQRLLDL 1572
>gi|2772930|gb|AAB96643.1| Genghis Khan [Drosophila melanogaster]
Length = 1613
Score = 937 bits (2423), Expect = 0.0
Identities = 589/1600 (36%), Positives = 885/1600 (54%), Gaps = 61/1600 (3%)
Frame = -1
Query: 4683 SFETLIDSLICLYDECCNSTLRKEKCIAEFVESVKTVISKAKKLRLSRDDFEVLKVIGKG 4504
S + L+D+ I LYDEC NS+LR+EK +++F++ K + +KLRLSRDDF++LK+IG+G
Sbjct: 26 SLDYLLDTFIVLYDECSNSSLRREKGVSDFLKLSKPFVHIVRKLRLSRDDFDILKIIGRG 85
Query: 4503 AFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACFREERDVLVYGDRRWITNLHYAFQD 4324
AFGEV VV+M ++YAMKILNKWEM+KRAETACFREERDVLV+GDR+WITNLHYAFQD
Sbjct: 86 AFGEVCVVQMISTEKVYAMKILNKWEMLKRAETACFREERDVLVFGDRQWITNLHYAFQD 145
Query: 4323 EKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDN 4144
NLY VMDYY GGD+LTLLSKF D +PE MAKFYI EM+LAI+S+H++ YVHRD+KPDN
Sbjct: 146 NINLYLVMDYYCGGDLLTLLSKFEDKLPEDMAKFYITEMILAINSIHQIRYVHRDIKPDN 205
Query: 4143 VLLDMQGHIRLADFGSCLRILADGSVASNVAVGTPDYISPEILRAMEDGRGRYGKECDWW 3964
VLLD +GH+RLADFGSCLR+ DG+V SNVAVGTPDYISPEILRAMEDG+GRYG ECDWW
Sbjct: 206 VLLDKRGHVRLADFGSCLRLDKDGTVQSNVAVGTPDYISPEILRAMEDGKGRYGTECDWW 265
Query: 3963 SLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDMLDFPDDE-IDWVVSEEAKDLIRQLIC 3787
SLG+CMYEMLYG TPFY+E LV+TYGKIM+HQ+ + P E +++ VSE ++DL+ +LIC
Sbjct: 266 SLGVCMYEMLYGETPFYAESLVETYGKIMNHQNCFNLPSQETLNYKVSETSQDLLCKLIC 325
Query: 3786 SSDVRFGRNGLSDFQLHPFFEGIDWNTIRDSNPPYVPEVSSPEDTSNFDVDVCEDDFTPC 3607
+ R G+NG+ DF HP+F GIDW IR PYVPEVSSP DTSNFDV DD
Sbjct: 326 IPENRLGQNGIQDFMDHPWFVGIDWKNIRQGPAPYVPEVSSPTDTSNFDV----DDNDVR 381
Query: 3606 LQETQPPRVLAAFTGNHLPFVGFSY--THGSLLSDARSLTDEIRAIAQRCQGDAELMEKS 3433
L ++ PP AF+G HLPF+GF++ T S L ++ + GD L S
Sbjct: 382 LTDSIPPSANPAFSGFHLPFIGFTFSLTSSSTLDSKKNQSSGF--------GDDTLDTIS 433
Query: 3432 VDGFMVELENEKAELVQKLKEAQTIIAQHVAENPRSEEDRNYESTIAQLKDEIQILNKRL 3253
+ N V ++ + ++E + + +LK + L +
Sbjct: 434 SPQLAILPSNNSETPVDSVQLKALNDQLAALKQEKAELSKQHNEVFERLKTQDSELQDAI 493
Query: 3252 EDEALAQQQQKPKDEIVAXXXXXXXXXXERNKQLVMEKSEIQRELDNINDHLDQVLVEKA 3073
+A + E + +L +K ++ R++ + + LD + +
Sbjct: 494 SQRNIAMMEYSEVTE--------------KLSELRNQKQKLSRQVRDKEEELDGAMQKND 539
Query: 3072 TV---VQQRDDMQAELADVGDSLLTEKDSVKRLQDEAEKAKKQVADFXXXXXXXXXXXXX 2902
++ +++ D + EL + + E K+L++ AE +Q+
Sbjct: 540 SLRNELRKSDKTRRELELHIEDAVIEAAKEKKLREHAEDCCRQLQMELRKGSSSVETTMP 599
Query: 2901 XXXKQEEVTIE-ARKSVETDDHLSE-------EVVAAKNTIASLQATNEERETEIKKLKQ 2746
E + E R ++ + LS E+ A + + L+ N E+++ ++
Sbjct: 600 LSISSEMSSYEIERLELQFSEKLSHQQTRHNMELEALREQFSELENANLALTKELQQTQE 659
Query: 2745 RMDEERASHTAQSEQEMKQLEAHYERAQKMLQDNVE----QMNVENRGLR------DEI- 2599
R+ + S + + +L+ ++ + + + ++N++++ L+ DEI
Sbjct: 660 RLKYTQMESITDSAETLLELKKQHDLEKSSWFEEKQRLSSEVNLKSKSLKELQAEDDEIF 719
Query: 2598 EKLSQQMAALPRGGLNEQQLHEIFNWVSEEKATREEMENLTRKITGEVESLKNNSPLTTS 2419
++L + A+ L E+Q+ EI WVS+EK R ++ L K+T E+E LK+ +
Sbjct: 720 KELRMKREAIT---LWERQMAEIIQWVSDEKDARGYLQALATKMTEELEYLKHVGTF-NN 775
Query: 2418 NYIQNTPSGWGSRRMNNVARKDGLDLQRQLQAEIDAKLKLKAELKNSQEQYLTSAARLDD 2239
N + N W +RR + + + L+LQ LQ EI AK + EL ++ +++ + D
Sbjct: 776 NGVDN--KNWRNRRSQKLDKMELLNLQSALQREIQAKNMISDELSQTRSDLISTQKEVRD 833
Query: 2238 TEKRMASLM-----REVAMLKQQKNIENSSDSAFSSTMGRGDLMISMNNDYEMSNSSLMR 2074
+KR S++ +E + +K S+S + + G L + D ++ +
Sbjct: 834 YKKRYDSILHDFQKKETELRDFEKGGLEYSESFLNKSTHHG-LSSAFFRDMSKNSEIIDS 892
Query: 2073 QEMISRQS----TPSY---ENAILLHDHQVPKRVDDLRYKQKPMKTASGI---------- 1945
E +S TP++ N+ +L +++ PK MK AS
Sbjct: 893 AESFGNESGDNFTPNFFQSGNSGMLFNYE-PKYAGKNNKDHSSMKEASVSDLSREESDQL 951
Query: 1944 --FSPVSISAMERGHNFERMKIKTPTKCGHCTSILIGLDRQGLFCQSCQYACHVSCAERV 1771
S + H F +PTKC HCTS+++GL RQG+ C+ C +ACH C ++V
Sbjct: 952 VKESQKKVPGNTAIHQFLVRTFSSPTKCNHCTSLMVGLTRQGVVCEICGFACHTICCQKV 1011
Query: 1770 SQSCPVP-EEERRPLGIDPTRGVGTAYEGLVKTPRAGGVRKGWQTAYVVVCDFKLYLYDC 1594
+CPVP ++ +RPLGIDPTRG+GTAYEG VK P++G +++GW +VVVCDFKL+LYD
Sbjct: 1012 PTTCPVPMDQTKRPLGIDPTRGIGTAYEGYVKVPKSGVIKRGWIRQFVVVCDFKLFLYDI 1071
Query: 1593 TVDRQNKMQDVKNEIRLVLDMRDPDFTVCGVSEADVIHAQKGDIPKIFRVTTTQILNXXX 1414
+ DR + V + VLDMRDP+F+V V E+DVIHA K D+P IF++ T I
Sbjct: 1072 SPDR-CALPSV--SVSQVLDMRDPEFSVGSVRESDVIHAAKKDVPCIFKIKTALI----- 1123
Query: 1413 XXXXXSKFYTLFMAETEEEKRKWVVALSELKTLLRRSKLADRKAFLVKEVFDVTTLPSIR 1234
TL +A+ E EK KWV+AL EL +L+R+ L + F V E+ D TL IR
Sbjct: 1124 --DGGLSLNTLMLADNESEKSKWVIALGELHRILKRNSLPNTAIFKVNEILD-NTLSLIR 1180
Query: 1233 VAQCCAIIDRSKIVIGFSDHGLYCIEISRQLLIPVGGEKENKQRCVETVEYDEAEQLLMM 1054
A C II ++I++G D GL+ I + + + +G K+ Q + Y E EQ+L++
Sbjct: 1181 NALCSVIIYPNQILLGTED-GLFYINLDQYEIARIGESKKILQ-----LWYIEEEQILVI 1234
Query: 1053 IVGPAKDRHVRIVPSAALDGRDLKWIKVNDTKGCHLLAVGTNNPGGRAGF-FAVAFKK-- 883
+ G K R++R++P AL+ D++WIKV ++K C G + F +A K+
Sbjct: 1235 LCG--KQRNLRLLPIRALEASDVEWIKVVESKNCISACTGIIRGFPNIVYSFIIALKRPN 1292
Query: 882 ---SVTIFQIDRSEKRHKKWKDLAMPGTPQSIAIFNG-RLYVGFSHSFRSWSLVGVDSSP 715
+ +++I+R+ RH+K + + Q + I + RL V F ++ L G ++
Sbjct: 1293 NHTQIVVYEINRTRTRHQKTCEFTIGYMAQHLQILSDMRLVVAHQSGFTAYFLRGEATA- 1351
Query: 714 VGSGDASGAVLQHISLVNMEDTSLQFLNQQTSYEAKLIVNV----PGSPDEYLLVFNMIG 547
+SLV+ E+ FLN + +A ++ + G+ EYLLVF +
Sbjct: 1352 -------------MSLVHPENQLCAFLN-YSGVDAVRVIEILCPSGGNFGEYLLVFQTLA 1397
Query: 546 LYVNEMGRRSRLPEVMFPTQAKYFAYHEPYLCVFSENEVDIFNVTLAEWVQTINLRSAKP 367
+YV+ GR+SR E+M+P Y + + +L VFS+ +DIFN AEWVQ+I L+ + P
Sbjct: 1398 IYVDLQGRKSRDREIMYPAFPTYITFCDGHLLVFSDTHLDIFNTQTAEWVQSIGLKQSLP 1457
Query: 366 LSGDGILSTCLCNDSPIFVLLQNVLQDQDSIEVPVNLASGSTDGXXXXXXXXXXXTIGKD 187
L+ G + ND+P+ V L N+ + + G+ G I K
Sbjct: 1458 LNNLGNVVLSSVNDTPLIVYLSNI-----HTKGLLQYRDGNRKGLPSIKRRFSIREINKT 1512
Query: 186 DRSASERRSHIQISTPSDFMHIVHMGPAPVMELQQNFIDL 67
+ S+RRS + IS P++F HI HMGP ++ Q +DL
Sbjct: 1513 IK--SDRRSKM-ISAPTNFNHISHMGPGDGIQ-NQRLLDL 1548
>gi|50748728|ref|XP_421380.1| PREDICTED: similar to KIAA1124 protein
[Gallus gallus]
Length = 2398
Score = 914 bits (2361), Expect = 0.0
Identities = 600/1702 (35%), Positives = 897/1702 (52%), Gaps = 189/1702 (11%)
Frame = -1
Query: 4626 TLRKEKCIAEFVESVKTVISK---------AKKLRLSRDDFEVLKVIGKGAFGEV----- 4489
T + + CI +++ + S K+++L RDDFE++KVIG+GAFGEV
Sbjct: 303 TAKSDMCILQYLPVSSVIFSAFHSRPFTKLVKEMQLHRDDFEIIKVIGRGAFGEVSSRQK 362
Query: 4488 ------------------------------------AVVRMRGVGEIYAMKILNKWEMVK 4417
AVV+M+ IYAMKILNKWEM+K
Sbjct: 363 RRWNLARDSFTHYRPKCQYQMASEDRNAARGFYETVAVVKMKCTERIYAMKILNKWEMLK 422
Query: 4416 RAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPE 4237
RAETACFREER+VLV GD +WIT LHYAFQDE LY VMDYY+GGD+LTLLSKF D +PE
Sbjct: 423 RAETACFREERNVLVNGDCQWITTLHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPE 482
Query: 4236 SMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASN 4057
MA+FYI EMVLAI S+H L YVHRD+KPDNVLLDM GHIRLADFGSCL++ DG+V S+
Sbjct: 483 DMARFYIGEMVLAIHSIHELHYVHRDIKPDNVLLDMNGHIRLADFGSCLKMSEDGTVQSS 542
Query: 4056 VAVGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIM 3877
VAVGTPDYISPEIL+AMEDG G+YG ECDWWSLG+CMYEMLYG TPFY+E LV+TYGKIM
Sbjct: 543 VAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIM 602
Query: 3876 SHQDMLDFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIRD 3697
+H++ FP D VSEEAKDLI++LICS + R G+NG+ DF+ H FFEG++W+ IR+
Sbjct: 603 NHEERFQFPSHVTD--VSEEAKDLIQRLICSRERRLGQNGIEDFKSHAFFEGLNWDNIRN 660
Query: 3696 SNPPYVPEVSSPEDTSNFDVDVCEDDFTPCLQETQPPRVLAAFTGNHLPFVGFSYTHGSL 3517
PY+P+VSSP DTSNFDV DD E PP F+G HLPFVGF+YT S
Sbjct: 661 LEAPYIPDVSSPSDTSNFDV----DDDVLRNPEVVPPSSHTGFSGLHLPFVGFTYTTDSS 716
Query: 3516 LSDARSLTDEIRAIAQRCQGDAELMEKS---VDGF---MVELENEKAELVQKLKEAQTII 3355
LSD +L +++ D + K+ ++G+ + +LE EK +L +KL+E+ T
Sbjct: 717 LSDRGTLKSAMQSDTVTNDVDVQRDLKNTSQIEGYEKKIRKLEQEKQDLNRKLQES-TQT 775
Query: 3354 AQHVAENPRSEEDRNYESTIAQLKDEIQILNKRLED---------EALAQQQQ------- 3223
Q + + N + I +L +EI+ L +L D +A+A +Q+
Sbjct: 776 VQSLQGPACVTVNTNRDREIKKLNEEIERLKNKLTDVSKLEGQLADAVAFRQEHEDCMHK 835
Query: 3222 ------------KPKDEIVAXXXXXXXXXXERNKQL----------VMEKSEIQR---EL 3118
+ K+++ ++K+L V E SE+ EL
Sbjct: 836 LKGLEKQCRVLRQEKEDLHKQLVEASERLKTQSKELRDAHQQRKLAVQEFSELSERMGEL 895
Query: 3117 DNINDHLDQVLVEKATVVQ---QRDD-----------MQAELADVGDSLLTEKDSVKRLQ 2980
+ L + L +K V+ Q++D ++ EL + ++ E ++L+
Sbjct: 896 RSQKQKLSRQLRDKEEEVEMSLQKNDAMRQDIRKSEKIRKELESQLEEVMAEASKERKLR 955
Query: 2979 DEAEKAKKQVADFXXXXXXXXXXXXXXXXKQEEVTIEARKS-VETDDHLSEEVVAAKNTI 2803
+ +E KQ+ + + + + K+ +E EE + +
Sbjct: 956 EHSEVFCKQLENELEALKVKQGGRAAGATLEHQQELSKMKAELEKKILFYEEELVRREAS 1015
Query: 2802 ASLQATNEERET------------EIKKLKQRMDEERASHTAQSEQEMKQLEAHYERAQK 2659
L+ N ++E EI LK ++++ + ++ E+ + ++ YER +
Sbjct: 1016 HVLEVKNVKKEVHDSESHQLALQKEIMILKDKLEKTKRERHSEMEEAVGSMKEKYERERS 1075
Query: 2658 ML-QDN-------------VEQMNVENRGLRDEIEKLSQQMAALPRGGLNEQQLHEIFNW 2521
ML +DN V+++ +NR L DE++ L+ + ++ E Q+ EI W
Sbjct: 1076 MLIEDNKKLTTENEKLCSFVDKLTAQNRQLDDELQDLAAKKESVAHW---EAQIAEIIQW 1132
Query: 2520 VSEEKATREEMENLTRKITGEVESLKNNSPLTTSNYIQNTPSGWGSRRMNNVARKDGLDL 2341
VS+EK R ++ L K+T E+ESL+++S + + W RR + L+L
Sbjct: 1133 VSDEKDARGYLQALASKMTEELESLRSSSLGS-----RTLDPLWKVRRSQKLDMSARLEL 1187
Query: 2340 QRQLQAEIDAKLKLKAELKNSQEQYLTSAARLDDTEKRMASLMREVAMLKQQKNIENSSD 2161
Q L AEI AK ++ EL+ ++ ++ ++L ++E + L+ E+ L+++ + +D
Sbjct: 1188 QSALDAEIRAKQLVQEELRKVKDANISFESKLKESEAKNRELLEEMEGLRKKLEEKYRTD 1247
Query: 2160 SAFSSTMGRGDLMISMN-----NDYEMSNSSLMRQEMISRQSTPSYENAILLHDHQVPKR 1996
S + + N D S+ QE +S S +++ + +
Sbjct: 1248 SGLKLPDFQDSIFEYFNTSPLARDLTFRTGSISEQETQGPKSEVSPSTSVVTAEQ---PQ 1304
Query: 1995 VDDLRYKQKPMKTASGIFSPVSISAMERGHNFERMKIKTPTKCGHCTSILIGLDRQGLFC 1816
+ +R ++ P + I S + H +PT+C HCTS+++GL RQG C
Sbjct: 1305 EEPIRLQRMPAAPSPTIQSISLAVPKPKAHQLNIKSFTSPTQCSHCTSLMVGLVRQGYAC 1364
Query: 1815 QSCQYACHVSCAERVSQSCPV-PEEERRPLGIDPTRGVGTAYEGLVKTPRAGGVRKGWQT 1639
C +ACHVSC + Q CP+ PE+ +RPLG+D RG+GTAY+G VK P+ GV+KGWQ
Sbjct: 1365 DVCSFACHVSCKDSAPQVCPIPPEQAKRPLGVDVQRGIGTAYKGYVKVPKPTGVKKGWQR 1424
Query: 1638 AYVVVCDFKLYLYDCTVDRQNKMQDVKNEIRLVLDMRDPDFTVCGVSEADVIHAQKGDIP 1459
AY VVCD KL+LYD + + V ++ VLD+RD DF+V V DVIHA + DIP
Sbjct: 1425 AYAVVCDCKLFLYDVPEGKSTQPGVVASQ---VLDLRDEDFSVSSVLAPDVIHATRKDIP 1481
Query: 1458 KIFRVTTTQILNXXXXXXXXSKFYTLFMAETEEEKRKWVVALSELKTLLRRSKLADRKAF 1279
IFRVT + + L + E E EKRKWV L L+++L +++L ++
Sbjct: 1482 CIFRVTASLL------GLPSKSCSLLILTENENEKRKWVGILEGLQSILHKNRLKNQVVH 1535
Query: 1278 LVKEVFDVTTLPSIRVAQCCAIIDRSKIVIGFSDHGLYCIEISRQLL---IPVGGEKENK 1108
+ +E +D +TLP I+ + AI+DR +I IG S+ GLY IE++R + + VG +K
Sbjct: 1536 IPQEAYD-STLPLIKASLAAAIVDRDRIAIG-SEEGLYVIEVTRDDIKCPLAVGLLYSDK 1593
Query: 1107 Q---------------------------------RCVETVEYDEAEQLLMMIVGPAKDRH 1027
+ V +E E+++++I G ++ H
Sbjct: 1594 AFANTNSILYPQFLALNTLHFFSLCSVIVRAADCKKVYQIELAPKEKIIILICG--RNHH 1651
Query: 1026 VRIVPSAALDGRDLKW-IKVNDTKGCHLLAVGTNNPGGRAGFFAVAFKKSVTIFQIDRSE 850
V + P A LDG + + IK+ +TKGC L+ GT F VA K+ V ++I R++
Sbjct: 1652 VHLFPWATLDGSEGSFDIKLAETKGCQLITTGTLKKSSATCLF-VAVKRQVFCYEIHRTK 1710
Query: 849 KRHKKWKDLAMPGTPQSIAIFNGRLYVGFSHSFRSWSLVGVDSSPVGSGDASGAVLQHIS 670
HKK+ ++ PGT Q + +F +L VG+ F SL+ + G G Q I+
Sbjct: 1711 PFHKKFSEIQAPGTVQWMTVFKDKLCVGYQSGF---SLLTIQ----GDG-------QSIN 1756
Query: 669 LVNMEDTSLQFLNQQTSYEAKLIVNVPGSPDEYLLVFNMIGLYVNEMGRRSRLPEVMFPT 490
LVN D SL FL+QQ S++A V + S +EYLL F+ +G+YV+ GRRSR+ E+M+P
Sbjct: 1757 LVNPNDPSLMFLSQQ-SFDALCAVEL--SNEEYLLCFSHMGVYVDSQGRRSRMQELMWPA 1813
Query: 489 QAKYFAYHEPYLCVFSENEVDIFNVTLAEWVQTINLRSAKPLSGDGILSTCLCNDSPIFV 310
+ + Y+ V+SE VD+F+V EWVQTI LR +PL+ DG L+ C + P +
Sbjct: 1814 TPVACSCNSSYVTVYSEYGVDVFDVNTMEWVQTIGLRRIRPLNMDGTLNLLNC-EPPRLI 1872
Query: 309 LLQNVLQDQDSIEVPVNLASGSTDGXXXXXXXXXXXTIGKDDRSASERRSHIQ------- 151
+N + VP + + +++R +RR ++
Sbjct: 1873 YFKNKFAVGAVLSVPETSDNSKKQMLRTRSKRRFVFKVPEEER-IQQRREMLRDPELRSK 1931
Query: 150 -ISTPSDFMHIVHMGPAPVMEL 88
IS P++F H+ HMGP M++
Sbjct: 1932 MISNPTNFNHVAHMGPGDGMQV 1953
Score = 51.6 bits (122), Expect = 2e-04
Identities = 24/54 (44%), Positives = 38/54 (69%), Gaps = 1/54 (1%)
Frame = -1
Query: 4746 VRLKTLENIYMDGPSKKPEALSFETLIDSLICLYDECC-NSTLRKEKCIAEFVE 4588
VRLK LE + +DGP + LS ETL+D L+ +Y EC +S LR+++ +++F+E
Sbjct: 79 VRLKRLEQLVLDGPQRNDSVLSVETLLDLLVGVYAECSRDSPLRRDRYVSDFLE 132
>gi|50878265|ref|NP_059995.1| myotonic dystrophy protein kinase like
protein; protein kinase [Homo sapiens]
gi|49616623|gb|AAT67172.1| myotonic dystrophy kinase-related
CDC42-binding kinase gamma [Homo sapiens]
Length = 1551
Score = 870 bits (2247), Expect = 0.0
Identities = 560/1568 (35%), Positives = 831/1568 (52%), Gaps = 21/1568 (1%)
Frame = -1
Query: 4743 RLKTLENIYMDGPSKKPEALSFETLIDSLICLYDECCNSTLRKEKCIAEFVESVKTVISK 4564
RL+ LE + P + L+D L+ L+ E + LR+E+ +A+F+ +SK
Sbjct: 4 RLRALEQLARGEAGGCP---GLDGLLDLLLALHHELSSGPLRRERSVAQFLSWASPFVSK 60
Query: 4563 AKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACFREER 4384
K+LRL RDDFE+LKVIG+GAFGEV VVR R G+I+AMK+L+KWEM+KRAETACFREER
Sbjct: 61 VKELRLQRDDFEILKVIGRGAFGEVTVVRQRDTGQIFAMKMLHKWEMLKRAETACFREER 120
Query: 4383 DVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFYIAEMV 4204
DVLV GD RW+T LHYAFQDE+ LY VMDYY GGD+LTLLS+F D +P +A+FY+AEMV
Sbjct: 121 DVLVKGDSRWVTTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPELAQFYLAEMV 180
Query: 4203 LAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASNVAVGTPDYISP 4024
LAI SLH+LGYVHRDVKPDNVLLD+ GHIRLADFGSCLR+ +G V S+VAVGTPDYISP
Sbjct: 181 LAIHSLHQLGYVHRDVKPDNVLLDVNGHIRLADFGSCLRLNTNGMVDSSVAVGTPDYISP 240
Query: 4023 EILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDMLDFPDD 3844
EIL+AME+G+G YG +CDWWSLG+C YE+L+G TPFY+E LV+TYGKIM+H+D L FP D
Sbjct: 241 EILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPD 300
Query: 3843 EIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIRDSNPPYVPEVSS 3664
D V A+DLIRQL+C + R GR GL DF+ HPFFEG+DW + S PY+PE+
Sbjct: 301 VPD--VPASAQDLIRQLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASSTAPYIPELRG 358
Query: 3663 PEDTSNFDVDVCEDDFTPCLQETQPPRVLAAFTGNHLPFVGFSYTHGSLLSDARSLTDEI 3484
P DTSNFDV DD T T PP AF+G+HLPFVGF+YT GS S ++
Sbjct: 359 PMDTSNFDV----DDDTLNHPGTLPPPSHGAFSGHHLPFVGFTYTSGS--HSPESSSEAW 412
Query: 3483 RAIAQRCQGDAELMEKSVDGFMVELENEKAELVQKLKEAQTIIAQHVAENPRSEEDRNYE 3304
A+ ++ Q LE EK EL +K +EA H
Sbjct: 413 AALERKLQC---------------LEQEKVELSRKHQEALHAPTDH-------------- 443
Query: 3303 STIAQLKDEIQILNKR----LEDEALAQQQQKPKDEIVAXXXXXXXXXXERNKQLVMEKS 3136
+ QL+ E+Q L R L D+A Q P + S
Sbjct: 444 RELEQLRKEVQTLRDRLPEMLRDKASLSQTDGPPAGSPG------------------QDS 485
Query: 3135 EIQRELDNINDHLDQVLVEKATVVQQRDDMQAELADVGDSLLTEKDSVKRLQDEAEKAKK 2956
++++ELD ++ L + R +QA+ ++ + +++ ++RLQ+ E+
Sbjct: 486 DLRQELDRLHREL----------AEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAA 535
Query: 2955 QVADFXXXXXXXXXXXXXXXXKQEEVTIEARKSVETDDHLSE--EVVAAKNTIASLQATN 2782
+ + +V+ +R+ + + E + TI + TN
Sbjct: 536 TASQTRALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETN 595
Query: 2781 EERETEIKKLKQRMDEERASHTAQSEQEMKQLEAHYERAQKMLQDNVEQMNVENRGLRDE 2602
E + ++ +E A+ Q EQ + E A LQ+ +++ E L E
Sbjct: 596 GMGPPEGGPQEAQLRKEVAALREQLEQAHSHRRSGKEEALCQLQEENRRLSREQERLEAE 655
Query: 2601 I--EKLSQQMAALPRGGLN---EQQLHEIFNWVSEEKATREEMENLTRKITGEVESLKNN 2437
+ E+ S+Q R E QL +I +WV++EK +R ++ L K+ E+ESL+N
Sbjct: 656 LAQEQESKQRLEGERRETESNWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNV 715
Query: 2436 SPLTTSNYIQNTPSGWGSRRMNNVARKDGLDLQRQLQAEIDAKLKLKAELKNSQEQYLTS 2257
T + W +RR+ + L+LQ L+AEI AK L+ L QE L +
Sbjct: 716 GTQTLP--ARPLDHQWKARRLQKMEASARLELQSALEAEIRAKQGLQERLTQVQEAQLQA 773
Query: 2256 AARLDDTEKRMASLMREVAMLKQQKNIENSSDSAFSSTMGRGDLMISMNNDYEMSNSSLM 2077
RL + EK+ +L +E+AML+++ D+ S++ + + S
Sbjct: 774 ERRLQEAEKQSQALQQELAMLREELRARGPVDTKPSNS-------LIPFLSFRSSEKDSA 826
Query: 2076 RQEMISRQSTPSYENAILLHDHQVPKRVDDLRYKQKPMKTASGIFSPVSISAMERGHNFE 1897
+ IS ++T L + + R+ + + TA S + A H
Sbjct: 827 KDPGISGEATRHGGEPDLRPEGRRSLRMGAVFPRAPTANTA----STEGLPAKPGSHTLR 882
Query: 1896 RMKIKTPTKCGHCTSILIGLDRQGLFCQSCQYACHVSCAERVSQSCPVPEE-ERRPLGID 1720
+PTKC CTS+++GL RQGL C +C Y CH +CA + + CPVP + R LG+
Sbjct: 883 PRSFPSPTKCLRCTSLMLGLGRQGLGCDACGYFCHTTCAPQ-APPCPVPPDLLRTALGVH 941
Query: 1719 PTRGVGTAYEGLVKTPRAGGVRKGWQTAYVVVCDFKLYLYDCTVDRQNKMQDVKNEIRLV 1540
P G GTAYEG + PR GVR+GWQ + + D +L L+D ++ + V
Sbjct: 942 PETGTGTAYEGFLSVPRPSGVRRGWQRVFAALSDSRLLLFDAP---DLRLSPPSGALLQV 998
Query: 1539 LDMRDPDFTVCGVSEADVIHAQKGDIPKIFRVTTTQILNXXXXXXXXSKFYTLFMAETEE 1360
LD+RDP F+ V +DVIHAQ D+P+IFRVTT+Q+ + L +AE+E
Sbjct: 999 LDLRDPQFSATPVLASDVIHAQSRDLPRIFRVTTSQL------AVPPTTCTVLLLAESEG 1052
Query: 1359 EKRKWVVALSELKTLLRRSKLADRKAFLVKEVFDVTTLPSIRVAQCCAIIDRSKIVIGFS 1180
E+ +W+ L EL+ LL ++ R + +KE +D LP + C AI+D+ ++ +G +
Sbjct: 1053 ERERWLQVLGELQRLLLDARPRPRPVYTLKEAYD-NGLPLLPHTLCAAILDQDRLALG-T 1110
Query: 1179 DHGLYCIEISRQLLIPVGGEKENKQRCVETVEYDEAEQLLMMIVGPAKDRHVRIVPSAAL 1000
+ GL+ I + + VG + R V+ + + LL+++ G + VR+ A L
Sbjct: 1111 EEGLFVIHLRSNDIFQVG-----ECRRVQQLTLSPSAGLLVVLCG--RGPSVRLFALAEL 1163
Query: 999 DGRDLKWIKVNDTKGCHLLAVGTNNPGGRAGFFAVAFKKSVTIFQIDRSE-KRHKKWKDL 823
+ ++ K+ +++GC +LA G+ R VA K+ V +Q+ ++ ++L
Sbjct: 1164 ENIEVAGAKIPESRGCQVLAAGSILQ-ARTPVLCVAVKRQVLCYQLGPGPGPWQRRIREL 1222
Query: 822 AMPGTPQSIAIFNGRLYVGFSHSFRSWSLVGVDSSPVGSGDASGAVLQHISLVNMEDTSL 643
P T QS+ + RL VG + F + L+ +++P+ G +G V +
Sbjct: 1223 QAPATVQSLGLLGDRLCVGAAGGFALYPLLN-EAAPLALG--AGLVPEE----------- 1268
Query: 642 QFLNQQTSYEAKLIVNVPGSPDEYLLVFNMIGLYVNEMGRRSRLPEVMFPTQAKYFAYHE 463
L + + V S E+LL+F G+YV+ GR+SR E+++P + Y
Sbjct: 1269 --LPPSRGGLGEALGAVELSLSEFLLLFTTAGIYVDGAGRKSRGHELLWPAAPMGWGYAA 1326
Query: 462 PYLCVFSENEVDIFNVTLAEWVQTINLRSAKPLSGDGILSTCLCNDSPIFVLLQNVLQDQ 283
PYL VFSEN +D+F+V AEWVQT+ L+ +PL+ +G L + L+N L ++
Sbjct: 1327 PYLTVFSENSIDVFDVRRAEWVQTVPLKKVRPLNPEGSL-FLYGTEKVRLTYLRNQLAEK 1385
Query: 282 DSIEVPVNLASGSTDGXXXXXXXXXXXTIGKDDRSASERRSHIQ--------ISTPSDFM 127
D ++P +L S +++ +RR ++ IS P++F
Sbjct: 1386 DEFDIP-DLTDNSRRQLFRTKSKRRFFFRVSEEQQKQQRREMLKDPFVRSKLISPPTNFN 1444
Query: 126 HIVHMGPA 103
H+VH+GPA
Sbjct: 1445 HLVHVGPA 1452
>gi|34861838|ref|XP_219530.2| hypothetical protein XP_219530 [Rattus
norvegicus]
Length = 1583
Score = 857 bits (2215), Expect = 0.0
Identities = 559/1576 (35%), Positives = 828/1576 (52%), Gaps = 30/1576 (1%)
Frame = -1
Query: 4743 RLKTLENIYMDGPSKKPEALSFETLIDSLICLYDECCNSTLRKEKCIAEFVESVKTVISK 4564
RL+ LE + P + L+D L+ ++ E ++ LR+E+ +A+F+ ++K
Sbjct: 4 RLRALEQLVRGEAGGSP---GLDGLLDLLLGVHQELSSAPLRRERNVAQFLSWAGPFVTK 60
Query: 4563 AKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACFREER 4384
K+LRL RDDFE+LKVIG+GAFGEVAVVR R G+I+AMK+L+KWEM+KRAETACFREER
Sbjct: 61 VKELRLQRDDFEILKVIGRGAFGEVAVVRQRDSGQIFAMKMLHKWEMLKRAETACFREER 120
Query: 4383 DVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFYIAEMV 4204
DVLV GD RW+T LHYAFQDE+ LY VMDYY GGD+LTLLS+F D +P +A+FY+AEMV
Sbjct: 121 DVLVKGDSRWVTALHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPELAQFYLAEMV 180
Query: 4203 LAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASNVAVGTPDYISP 4024
LAI SLH+LGYVHRDVKPDN+LLDM GHIRLADFGSCLR+ +G V S+VAVGTPDYISP
Sbjct: 181 LAIHSLHQLGYVHRDVKPDNILLDMNGHIRLADFGSCLRLNNNGMVDSSVAVGTPDYISP 240
Query: 4023 EILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDMLDFPDD 3844
EIL+AME+G+G YG +CDWWSLG+C YE+L+G TPFY+E LV+TYGKIM+H+D L FP D
Sbjct: 241 EILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPSD 300
Query: 3843 EIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIRDSNPPYVPEVSS 3664
D V A+ LIRQL+C + R GR GL DF+ HPFFEG+DW + S PY+PE+
Sbjct: 301 VDD--VPASAQALIRQLLCRQEERLGRGGLDDFRSHPFFEGVDWERLATSTAPYIPELRG 358
Query: 3663 PEDTSNFDVDVCEDDFTPCLQETQPPRVLAAFTGNHLPFVGFSYTHGSLLSDARSLTDEI 3484
P DTSNFDV DD T ET PP AF+G+HLPFVGF+YT GSL D S E+
Sbjct: 359 PVDTSNFDV----DDDTLNRPETLPPSSHGAFSGHHLPFVGFTYTSGSLTDDKSS---EL 411
Query: 3483 RAIAQRCQGDAELMEKSVDGFMVELENEKAELVQKLKEAQTIIAQHVAENPRSEEDRNYE 3304
A + E M K EL QK +E A H + P+
Sbjct: 412 MATPEWKPHGVEQM--------------KVELSQKCQE-----ALHSSLQPQE------- 445
Query: 3303 STIAQLKDEIQILNKRLEDEALAQQQQKPKDEIVAXXXXXXXXXXERNKQLVMEKSEIQR 3124
+ +L+ E+Q+L ++L + + ++ + QL EK +Q+
Sbjct: 446 --LVRLQKEVQVLQEKLTETL------RDSKASLSQADGLHVRSPAPDIQLQQEKDRLQQ 497
Query: 3123 ELDNINDHL-------------DQVLVEKATVVQQRDDMQAELADVGDSLLTEKDSVKR- 2986
EL L + +++ Q+R+ A +S L E V+R
Sbjct: 498 ELAEAQAALQVRDAELCQAQNRQEEFLQRLWEAQEREAAAASQIQALNSQLEEAWVVRRE 557
Query: 2985 LQDEAEKAKKQVADFXXXXXXXXXXXXXXXXKQEEVTIEARKSVETDDHLSEEVVAAKNT 2806
+ D++ K + + + +V +++ + ++ + T
Sbjct: 558 VGDDSGKGSSKCWESMSLAPAVAGYIGQGLALEGQVNTLSQEVTQLQGQCKQDSSSQAKT 617
Query: 2805 IASLQATNEERETEIKKLKQRMDEERASHTAQSEQEMKQ-LEAHYERAQKMLQDNVEQMN 2629
+ + TN E + + ++ +E A+ Q E Q + E LQ+ ++++
Sbjct: 618 VHAAPETNGIGSPEGQSQEAQLRKEVAALREQLECACSQGVNVGKEEVLCRLQEENQRLS 677
Query: 2628 VENRGLRDEIEKLSQQMAALPRGGLN-----EQQLHEIFNWVSEEKATREEMENLTRKIT 2464
E L +E++ Q L E Q+ +I +WV++EK +R ++ L K+
Sbjct: 678 REQERLAEELDLELQSRQRLEGERRESESNWEAQIADILSWVNDEKVSRGYLQALATKMA 737
Query: 2463 GEVESLKNNSPLTTSNYIQNTPSGWGSRRMNNVARKDGLDLQRQLQAEIDAKLKLKAELK 2284
E+ESL+N T + W +RR+ + L+LQ L+AEI AK L+ +L
Sbjct: 738 EELESLRNVGTQTLPT--RPLDHQWKARRLQKMEASARLELQSALEAEIRAKQGLQEQLT 795
Query: 2283 NSQEQYLTSAARLDDTEKRMASLMREVAMLKQQKNIENSSDSAFSSTMGRGDLMISMNND 2104
QE + RL + EK+ +L +EVA L+++ D+ ++ +I + +
Sbjct: 796 QVQEAQRQAERRLQEAEKQNQALQQEVAELREELQARGPGDAKPCTS------LIPLLSF 849
Query: 2103 YEMSNSSLMRQEMISRQSTPSYENAILLHDHQVPKRVDDLRYKQKPMKTASGIFSPVSIS 1924
+ S + S +S S A L + + R+ + + + P + P
Sbjct: 850 WNTEKDS-AKDPGNSGESPRSGAEAELRPEGRRSLRMGSV-FPRVPAANPTPAEGP---P 904
Query: 1923 AMERGHNFERMKIKTPTKCGHCTSILIGLDRQGLFCQSCQYACHVSCAERVSQSCPVPEE 1744
A H +PTKC HCTS+++GL RQGL C +C Y CH +CA + + CPVP E
Sbjct: 905 AKPGSHTLRPRSFPSPTKCLHCTSLMLGLGRQGLGCDTCGYFCHSACATQ-APPCPVPPE 963
Query: 1743 -ERRPLGIDPTRGVGTAYEGLVKTPRAGGVRKGWQTAYVVVCDFKLYLYDCTVDRQNKMQ 1567
R LG+ P G GTAYEG + PR GVR+GWQ Y + D +L L+D R +
Sbjct: 964 LLRTALGVHPETGTGTAYEGFLSVPRPSGVRRGWQRVYAALSDSRLLLFDAPDPRGSMAS 1023
Query: 1566 DVKNEIRLVLDMRDPDFTVCGVSEADVIHAQKGDIPKIFRVTTTQILNXXXXXXXXSKFY 1387
V + LD+RDP F+ V DVIHAQ D+P+IFRVT +Q+ S
Sbjct: 1024 GV---LLQALDLRDPQFSATPVLAPDVIHAQSKDLPRIFRVTASQL------TVPPSTCT 1074
Query: 1386 TLFMAETEEEKRKWVVALSELKTLLRRSKLADRKAFLVKEVFDVTTLPSIRVAQCCAIID 1207
L +AE E E+ +W+ LSEL+ LL ++ R + +KE +D LP + C AIID
Sbjct: 1075 VLLLAENEGERERWLQVLSELQRLLLDARPRPRPVYTLKEAYD-NGLPLLPHTLCAAIID 1133
Query: 1206 RSKIVIGFSDHGLYCIEISRQLLIPVGGEKENKQRCVETVEYDEAEQLLMMIVGPAKDRH 1027
R ++ +G ++ GL+ I + + VG R V+ + A LL+++ G +
Sbjct: 1134 RERLALG-TEEGLFVIHLHSNDIFQVG-----DCRRVQRLTVSSAAGLLVVLCG--RGPS 1185
Query: 1026 VRIVPSAALDGRDLKWIKVNDTKGCHLLAVGTNNPGGRAGFFAVAFKKSVTIFQIDRSE- 850
VR+ + L+ ++ K+ +++GC L G+ R VA K+ V +Q+
Sbjct: 1186 VRLFTLSELENAEVAGAKIPESRGCQALVAGSILQ-ARTPVLCVAVKRQVLCYQLGPGPG 1244
Query: 849 KRHKKWKDLAMPGTPQSIAIFNGRLYVGFSHSFRSWSLVGVDSSPVGSGDASGAVLQHIS 670
++ ++L P QS+ + RL VG + +F + L+ +++P+ G +G V +
Sbjct: 1245 PWQRRIRELQAPAPVQSLGLLGDRLCVGAAGTFALYPLLN-EAAPLALG--TGLVAEE-- 1299
Query: 669 LVNMEDTSLQFLNQQTSYEAKLIVNVPGSPDEYLLVFNMIGLYVNEMGRRSRLPEVMFPT 490
L + + V S E LL+F G+YV+ GR+SR E+++P
Sbjct: 1300 -----------LPASRGGLGEALGAVELSLSELLLLFATAGVYVDGAGRKSRSHELLWPV 1348
Query: 489 QAKYFAYHEPYLCVFSENEVDIFNVTLAEWVQTINLRSAKPLSGDGILSTCLCNDSPIFV 310
+ Y PYL VFSEN +D+F+V AEWVQT+ L+ +PL+ +G L +
Sbjct: 1349 APTGWGYTAPYLTVFSENSIDVFDVRRAEWVQTVPLKKVRPLNPEGSL-LLYGTEKVRLT 1407
Query: 309 LLQNVLQDQDSIEVPVNLASGSTDGXXXXXXXXXXXTIGKDDRSASERRSHIQ------- 151
L+N L ++D ++P +L S D+ +RR ++
Sbjct: 1408 YLRNPLAEKDEFDIP-DLTDNSRRQLFRTKSKRRFFFRVSDELRQQQRREMLKDPFVRSK 1466
Query: 150 -ISTPSDFMHIVHMGP 106
IS P++F H+VH+GP
Sbjct: 1467 FISPPTNFNHLVHVGP 1482
>gi|47213350|emb|CAF92973.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 1739
Score = 834 bits (2154), Expect = 0.0
Identities = 594/1802 (32%), Positives = 881/1802 (47%), Gaps = 247/1802 (13%)
Frame = -1
Query: 4755 SAPVRLKTLENIYMDGPSKKPEALSFETLIDSLICLYDECCNSTLRKEKCIAEFVESVKT 4576
SA VRLK LE + ++ K+ LS E L+ L+CL+ EC S LR+EK +A+F++ VK
Sbjct: 2 SAQVRLKRLEELLLE--QKEAGCLSVEALLALLLCLFSECSQSPLRREKHVADFLDWVKP 59
Query: 4575 VISKAKKLRLSRDDFEVLKVIGKGAFGE----------------------------VAVV 4480
+ K LRL RDDFE+LKVIG+GAFGE VAVV
Sbjct: 60 FSTTVKDLRLHRDDFEMLKVIGRGAFGEAALAAFVPANQKHSLSPCLWSRLSARPQVAVV 119
Query: 4479 RMRGVGEIYAMKILNKWEMVKRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVM 4300
+M+ +YAMKILNKWEM+KRAETACFREERDVLV GD +WIT LHYAFQDE LY VM
Sbjct: 120 KMKQTERVYAMKILNKWEMLKRAETACFREERDVLVRGDSQWITTLHYAFQDENFLYLVM 179
Query: 4299 DYYIGGDMLTLLSKFVDHIPESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGH 4120
DYY+GGD+LTLLSKF D +PE MAKFY+AEMVLAI S+H+ Y+HRD+KPDNVLLDM GH
Sbjct: 180 DYYVGGDLLTLLSKFEDRLPEDMAKFYLAEMVLAIHSIHQQHYIHRDIKPDNVLLDMNGH 239
Query: 4119 IRLADFGSCLRILADGSVASNVAVGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYE 3940
IRLADFGSCLR++ DG+V S+VAVGTPDYISPEIL+AMEDG GRYG ECDWWSLG+C+YE
Sbjct: 240 IRLADFGSCLRMMEDGTVQSSVAVGTPDYISPEILQAMEDGMGRYGPECDWWSLGVCLYE 299
Query: 3939 MLYGTTPFYSERLVDTYGKIMSHQDMLDFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRN 3760
MLYG TPFY+E LV+TYGKIM+H++ FP D VSE+AKDLI++LICS + R G N
Sbjct: 300 MLYGETPFYAESLVETYGKIMNHEERFQFPSHVSD--VSEDAKDLIQRLICSRERRLGLN 357
Query: 3759 GLSDFQLHPFFEGIDWNTIRDSNPPYVPEVSSPEDTSNFDVDVCEDDFTP---------- 3610
G+SDF+ H FF GIDW+ IR + PY+P+VSSP DTSNFDVD DD
Sbjct: 358 GISDFKSHGFFSGIDWDNIRSAEAPYIPDVSSPTDTSNFDVD---DDVLKNPVGTRTWIH 414
Query: 3609 --------------CLQETQPPRVLAAFTGNHLPFVGFSYTHGSLLSDARSLTDEIRAIA 3472
CLQE PP FTG HLPFVGF++T S +D S++ A A
Sbjct: 415 SPVWSVLGFLSVCVCLQEISPPLSHTGFTGQHLPFVGFTFTTNSCFADGGSISRAEAAPA 474
Query: 3471 QRCQGDAELMEKSVDGFMVELENEKAELVQKLKEAQTI---------------------- 3358
Q E E+ + LE EK EL +KL+E+
Sbjct: 475 AAGQ-QLEAFERRIR----RLEQEKQELNRKLQESTQALQAPRGGALARDKELKKLNEEI 529
Query: 3357 --IAQHVAENPRSEE--------DRNYESTIAQLK---DEIQILNK-------------- 3259
+ Q +A++ R E ++YES+ ++LK ++++L +
Sbjct: 530 ERLKQKLADSDRLEHQLEEAVMLQQDYESSASKLKTLEKQVKMLRQEKEEVHKVVPLQRE 589
Query: 3258 ------RLEDEALAQQQQKPKD--EIVAXXXXXXXXXXERNKQLVMEKSEI--------- 3130
RL EAL +Q+ D E + + K + E SE+
Sbjct: 590 GPLRWGRLCSEALVLCEQQLADALERLRSQSKELKEAHSQRKLALQEFSELSERLADLRS 649
Query: 3129 -----QRELDNINDHLDQVLVEKATVVQQ-------RDDMQAELADVGDSLLTEKD---- 2998
R+L + + +D +L + TV Q R D++A+L D E+
Sbjct: 650 SKQRLSRQLRDKEEEMDALLQKMDTVRQDIRKTEKIRKDLEAQLDDAKAEASKERKLREH 709
Query: 2997 ---SVKRLQDEAEKAKKQVADFXXXXXXXXXXXXXXXXKQEEVTIEA----------RKS 2857
K+L+ E E+ K +QE ++A +
Sbjct: 710 SELYSKQLETEVERLKVSGLSSALSQQGRGAPAGTAESQQEVSRVKAELDKKILFYEEEL 769
Query: 2856 VETDDHLSEEVVAAKNTIASLQATNEERETEIKKLKQRMDEERASHTAQSEQEMKQLEAH 2677
+ D LS E+ + + + E+ +L+ ++D+ + + ++ + L+
Sbjct: 770 LRRDSALSSEIKNLRKDLHESEGAQLSANKELLQLRDKLDKAKRDRQTEMDEAVAALKEK 829
Query: 2676 YERAQKMLQDN--------------VEQMNVENRGLRDEIEKLSQQMAALPRGGLNEQQL 2539
+ER + +L + V+++ +NR L D+++ LS + ++ E Q+
Sbjct: 830 HEREKNLLTEENRKLTAENDKICSLVDKLRAQNRQLEDDLQDLSSKKESVAHW---EAQI 886
Query: 2538 HEIFNWVSEEKATREEMENLTRKITGEVESLKNNSPLTTSNYIQNTPSGWGSRRMNNVAR 2359
EI + E+ ++ L K+T E+E+L+++S T + W RR +
Sbjct: 887 AEI---IQCEENAGGYLQALATKMTEELETLRSSSLGT-----RPLDPLWKVRRSQKLDM 938
Query: 2358 KDGLDLQRQLQAEIDAKLKLKAELK-------NSQEQYLTSAA----------------- 2251
L+LQ L AEI AK ++ EL+ N + +T +A
Sbjct: 939 SARLELQSALDAEIRAKQLVQEELRRVKAANINLERSEVTGSASACLCPPSSPSSRSRVC 998
Query: 2250 ---RLDDTEKRMASLMREVAMLK-QQKNIENSSDSAFSSTMGRGDLMISMNNDYEMSNSS 2083
++ D+E+R+ L ++ LK + + D S+ G S +
Sbjct: 999 VSSKVKDSEERIKELEEQMETLKTEMEESHGHHDKGGSTRTG------------SWSAPA 1046
Query: 2082 LMRQEMISRQSTPSYENAILLHDHQVPK------RVDDLRYKQKPMKTASGIFSPVSISA 1921
L+ + P ++++I + + P RV L + P + S P
Sbjct: 1047 LLIPGFSAGLKLPDFQDSIFDYFNTSPLAPDLTFRVSHLTRTETP-ASRSLRPRPPRPPP 1105
Query: 1920 MERGHNFERMKIKTPTKCGHCTSILIGLDRQGLFCQSCQYACHVSCAERVSQSCPVP-EE 1744
+ R H +PT+C HCTS+++GL RQG C+ C + CHVSC + CP+P E+
Sbjct: 1106 VSRAHQLSIKTFSSPTQCTHCTSLMVGLARQGYACEVCSFICHVSCKDHAPCVCPIPAEQ 1165
Query: 1743 ERRPLGIDPTRGVGTAYEGLVKT-------------------------PRAGGVRKGWQT 1639
+RP GID RG+GTAY+G V+ P+ GV+KGWQ
Sbjct: 1166 SKRPQGIDVQRGIGTAYKGYVRVSAGALCYASSAALASVANLCVVCQIPKPSGVKKGWQR 1225
Query: 1638 AYVVVCDFKLYLYDCTVDRQNKMQDVKNEIRLVLDMRDPDFTVCGVSEADVIHAQKGDIP 1459
VV D KL+LYD + K LVLD+R+ F+V V +DVIHA + D+P
Sbjct: 1226 VLAVVSDCKLFLYDVP---EGKSTQPGVGASLVLDLREEAFSVSSVLASDVIHATRKDVP 1282
Query: 1458 KIFRVTTTQILNXXXXXXXXSKFYTLFMAETEEEKRKWVVALSELKTLLRRSKLADRKAF 1279
IF++T++Q++ L +AE+E EKRKWV L L+++L ++ L
Sbjct: 1283 CIFKITSSQLIPALSSVS------LLVLAESEAEKRKWVRVLEGLQSILSKNLLRSHHVH 1336
Query: 1278 LVKEVFDVTTLPSIRVAQCCAII-----------DRSKIVIGFSDHGLYCIEISRQLLIP 1132
+ E +D +LP I+ A A++ DR +I +G D GL+ +E++R +++
Sbjct: 1337 VPHEAYD-ASLPVIKSALSAAVLAQVLVCVLVWADRERIALGTED-GLFVVEVTRDVIVR 1394
Query: 1131 VGGEKENKQRCVETVEYDEAEQLLMMIVGPAKDRHVRIVPSAALDGRDLKW-IKVNDTKG 955
K+ Q ++ E+++ ++ G ++R V + P LDG + + +K+ DTKG
Sbjct: 1395 AADSKKTYQ-----IDLIPKEKVVALLCG--RNRQVHLYPWEVLDGAEPTFDVKLTDTKG 1447
Query: 954 CHLLAVGTNNPGGRAGFFAVAFKKSVTIFQIDRSEKRHKKWKDLAMPGTPQSIAIFNGRL 775
C L G PGG A A A K+ V ++I RS+ +++ ++ PG Q + + RL
Sbjct: 1448 CQALTTGLLRPGGPACLLA-AVKRQVQCYEITRSKPHYRRLWEVQAPGPVQWLGMVRERL 1506
Query: 774 YVGFSHSFRSWSLVGVDSSPVGSGDASGAVLQHISLVNMEDTSLQFLNQQTSYEAKL--- 604
VG+ F L G ++SPV SLV+ D SL FL QQ S
Sbjct: 1507 CVGYPSGFALLGLQG-ETSPV-------------SLVSPADPSLAFLAQQPSGSLARPGG 1552
Query: 603 -IVNVPGSPDEYLLVFNMIGLYVNEMGR--RSRLPEVMFPTQAKYFAYHEPYLCVFSENE 433
++ + + G + + G + QA + +L V+SE
Sbjct: 1553 GLLGAAALLQPARRLRGLAGQALQDPGADVARHASRNQYVPQAGVGGSNWSHLTVYSEYG 1612
Query: 432 VDIFNVTLAEWVQTINLRSAKPLSGDGILSTCLCNDSPIFVLLQNVLQDQDSIEVPVNLA 253
VD+F++ A+W+QTI+L +PL+ +G L+ L P ++ + + + +P
Sbjct: 1613 VDVFDIHTADWLQTISLCKIRPLNAEGTLN--LLTSEPSRLIYFSNSCSEGELTIPDTSD 1670
Query: 252 SGSTDGXXXXXXXXXXXTIGKDDRSASER--------RSHIQISTPSDFMHIVHMGPAPV 97
+ +++R R RS + IS P++F H+ HMGP
Sbjct: 1671 HSRRLMVRTRSKRKFLFKVPEEERLQQRREMLRDPELRSRM-ISNPTNFNHVAHMGPGDG 1729
Query: 96 ME 91
M+
Sbjct: 1730 MQ 1731
>gi|38084833|ref|XP_140553.3| similar to BC046418 protein [Mus
musculus]
Length = 1453
Score = 773 bits (1995), Expect = 0.0
Identities = 515/1464 (35%), Positives = 757/1464 (51%), Gaps = 16/1464 (1%)
Frame = -1
Query: 4449 MKILNKWEMVKRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLT 4270
MK+L+KWEM+KRAETACFREERDVLV GD RW+T LHYAFQDE+ LY VMDYY GGD+LT
Sbjct: 1 MKMLHKWEMLKRAETACFREERDVLVKGDSRWVTALHYAFQDEEYLYLVMDYYAGGDLLT 60
Query: 4269 LLSKFVDHIPESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCL 4090
LLS+F D +P +A+FY+AEMVLAI SLH+LGYVHRDVKPDN+LLDM GHIRLADFGSCL
Sbjct: 61 LLSRFEDRLPPELAQFYLAEMVLAIHSLHQLGYVHRDVKPDNILLDMNGHIRLADFGSCL 120
Query: 4089 RILADGSVASNVAVGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYS 3910
R+ +G V S+VAVGTPDYISPEIL+AME+G+G YG +CDWWSLG+C YE+L+G TPFY+
Sbjct: 121 RLNNNGMVDSSVAVGTPDYISPEILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYA 180
Query: 3909 ERLVDTYGKIMSHQDMLDFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPF 3730
E LV+TYGKIM+H+D L FP D D V A+DLIRQL+C + R GR GL DF+ HPF
Sbjct: 181 ESLVETYGKIMNHEDHLQFPADVTD--VPASAQDLIRQLLCRQEERLGRGGLDDFRKHPF 238
Query: 3729 FEGIDWNTIRDSNPPYVPEVSSPEDTSNFDVDVCEDDFTPCLQETQPPRVLAAFTGNHLP 3550
FEG+DW + S PY+PE+ P DTSNFDVD D T ET PP AF+G+HLP
Sbjct: 239 FEGVDWERLATSTAPYIPELRGPMDTSNFDVD----DDTLNRPETLPPSSHGAFSGHHLP 294
Query: 3549 FVGFSYTHGSLLSDARSLTDEIRAIAQRCQGDAELMEKSVDGFMVELENEKAELVQKLKE 3370
FVGF+YT GS D +S +ELM + +G +E K EL K +E
Sbjct: 295 FVGFTYTSGSPF-DVQS---------------SELMA-APEGTPHCVEQVKVELSHKCQE 337
Query: 3369 AQTIIAQHVAENPRSEEDRNYESTIAQLKDEIQILNKRLEDEALAQQQQKPKDEIVAXXX 3190
H P+ + +L+ E+Q+L ++L + + ++
Sbjct: 338 PL-----HGPLQPQE---------LVRLQKEVQVLQEKLAETL------RDSKASLSQTD 377
Query: 3189 XXXXXXXERNKQLVMEKSEIQRELDNINDHLDQVLVEKATVVQQRDDMQAELADVGDSLL 3010
N QL EK +Q+EL + A VQ + QA+
Sbjct: 378 GLHARSPAPNIQLQQEKDRLQQELTE---------AQAALRVQDAELCQAQNR------- 421
Query: 3009 TEKDSVKRLQDEAEKAKKQVADFXXXXXXXXXXXXXXXXKQEEVTIEARKSVETDDHLSE 2830
+++ ++RL + E+ + + +VT +++ +
Sbjct: 422 -QEEFLQRLWEAQEREAAAASQIQALNSQLEEAWVVRRELEGQVTTLSQEVTRLQGQCKQ 480
Query: 2829 EVVAAKNTIASLQATNEERETEIKKLKQRMDEERASHTAQSEQEMKQ-LEAHYERAQKML 2653
E AK T+ + TN E + + ++ +E A+ Q E Q + E L
Sbjct: 481 ESSQAK-TVHAAPETNGIGSPEGQSQEAQLRKEVAALREQLEHACSQGISVGKEEVLCRL 539
Query: 2652 QDNVEQMNVENRGLRDEIEKLSQQMAALPRGGLN-----EQQLHEIFNWVSEEKATREEM 2488
Q+ ++++ E L E+E Q L E Q+ +I +WV++EK +R +
Sbjct: 540 QEENQRLSREQERLAGELELELQSKQRLEGERRETESNWEAQIADILSWVNDEKVSRGYL 599
Query: 2487 ENLTRKITGEVESLKNNSPLTTSNYIQNTPSGWGSRRMNNVARKDGLDLQRQLQAEIDAK 2308
+ L K+ E+ESL+N T + W +RR+ + L+LQ L+AEI AK
Sbjct: 600 QALATKMAEELESLRNVGTQTLPT--RPLDHQWKARRLQKMEASARLELQSALEAEIRAK 657
Query: 2307 LKLKAELKNSQEQYLTSAARLDDTEKRMASLMREVAMLKQQKNIENSSDSAFSSTMGRGD 2128
L+ +L QE + RL + EK+ +L +EVA L+++ D+ S++
Sbjct: 658 QSLQEQLTQVQEAQRQAERRLQEAEKQSQALQQEVAELREELQARGPGDARPSTS----- 712
Query: 2127 LMISMNNDYEMSNSSLMRQEMISRQSTPSYENAILLHDHQVPKRVDDLRYKQKPMKTASG 1948
+I + + + S + S + S A L + + R+ + + + P T +
Sbjct: 713 -LIPLLSFWNTEKDS-AKDPGNSGEGPRSGAEAELRPEGRRSLRMGSV-FPRVPAATTTP 769
Query: 1947 IFSPVSISAMERGHNFERMKIKTPTKCGHCTSILIGLDRQGLFCQSCQYACHVSCAERVS 1768
P A H +PTKC CTS+++GL RQGL C +C Y CH +CA + +
Sbjct: 770 AEGP---PAKPGSHTLRPRSFPSPTKCLRCTSLMLGLGRQGLGCDTCGYFCHSACASQ-A 825
Query: 1767 QSCPVPEE-ERRPLGIDPTRGVGTAYEGLVKTPRAGGVRKGWQTAYVVVCDFKLYLYDCT 1591
CPVP E R LG+ P G GTAYEG + PR GVR+GWQ Y + D +L L+D
Sbjct: 826 PPCPVPPELLRTALGVHPETGTGTAYEGFLSVPRPSGVRRGWQRVYAALSDSRLLLFDAP 885
Query: 1590 VDRQNKMQDVKNEIRLVLDMRDPDFTVCGVSEADVIHAQKGDIPKIFRVTTTQILNXXXX 1411
R + V + LD+RDP F+ V DVIHAQ D+P+IFRVT +Q+
Sbjct: 886 DPRGSLASGV---LLQALDLRDPQFSATPVLAPDVIHAQSKDLPRIFRVTASQL------ 936
Query: 1410 XXXXSKFYTLFMAETEEEKRKWVVALSELKTLLRRSKLADRKAFLVKEVFDVTTLPSIRV 1231
+ L +AE E E+ +W+ L EL+ LL ++ R + +KE +D LP +
Sbjct: 937 TVPPTTCTVLLLAENEGERERWLQVLGELQRLLLDARPRPRPVYTLKEAYD-NGLPLLPH 995
Query: 1230 AQCCAIIDRSKIVIGFSDHGLYCIEISRQLLIPVGGEKENKQRCVETVEYDEAEQLLMMI 1051
A C A+ID+ ++ +G ++ GL+ I + + VG R V+ + A LL ++
Sbjct: 996 ALCAAVIDQERLALG-TEEGLFVIHLHSNDIFQVG-----DCRRVQRLAVSSAAGLLAVL 1049
Query: 1050 VGPAKDRHVRIVPSAALDGRDLKWIKVNDTKGCHLLAVGTNNPGGRAGFFAVAFKKSVTI 871
G + VR+ L+ ++ K+ +++GC L G R VA K+ V
Sbjct: 1050 CG--RGPSVRLFALDELESAEVAGAKIPESRGCQALVAG-RILQARTPVLCVAVKRQVLC 1106
Query: 870 FQIDRSE-KRHKKWKDLAMPGTPQSIAIFNGRLYVGFSHSFRSWSLVGVDSSPVGSGDAS 694
+Q+ ++ ++L P QS+ + RL VG + +F + L+ +++P+ G +
Sbjct: 1107 YQLGPGPGPWQRRIRELQAPAPVQSLGLLGDRLCVGAAGTFALYPLLN-EAAPLALG--T 1163
Query: 693 GAVLQHISLVNMEDTSLQFLNQQTSYEAKLIVNVPGSPDEYLLVFNMIGLYVNEMGRRSR 514
G V + L + + V S E LL+F G+YV+ GR+SR
Sbjct: 1164 GLVAEE-------------LPASRGGLGEALGAVELSLSELLLLFATAGVYVDSAGRKSR 1210
Query: 513 LPEVMFPTQAKYFAYHEPYLCVFSENEVDIFNVTLAEWVQTINLRSAKPLSGDGILSTCL 334
E+++P + Y PYL VFSEN +D+F+V AEWVQT+ L+ +PL+ +G L
Sbjct: 1211 SHELLWPAAPTGWGYTAPYLTVFSENALDVFDVRRAEWVQTVPLKKVRPLNPEGSL-FLY 1269
Query: 333 CNDSPIFVLLQNVLQDQDSIEVPVNLASGSTDGXXXXXXXXXXXTIGKDDRSASERRSHI 154
+ L+N L ++D ++P +L S D+ +RR +
Sbjct: 1270 GTEKVRLTYLRNPLAEKDEFDIP-DLTDNSRRQLFRTKSKRRFFFRVSDELRQQQRREML 1328
Query: 153 Q--------ISTPSDFMHIVHMGP 106
+ IS P++F H+VH+GP
Sbjct: 1329 KDPFVRSKFISPPTNFNHLVHVGP 1352
>gi|38073634|ref|XP_283677.2| similar to CDC42-binding protein kinase
alpha; mytonic dystrophy kinase-related Cdc42-binding
kinase [Mus musculus]
Length = 1509
Score = 747 bits (1928), Expect = 0.0
Identities = 492/1452 (33%), Positives = 754/1452 (51%), Gaps = 104/1452 (7%)
Frame = -1
Query: 4131 MQGHIRLADFGSCLRILADGSVASNVAVGTPDYISPEILRAMEDGRGRYGKECDWWSLGI 3952
M GHIRLADFGSCL+++ DG+V S+VAVGTPDYISPEIL+AMEDG+GRYG ECDWWSLG+
Sbjct: 1 MNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDGKGRYGPECDWWSLGV 60
Query: 3951 CMYEMLYGTTPFYSERLVDTYGKIMSHQDMLDFPDDEIDWVVSEEAKDLIRQLICSSDVR 3772
CMYEMLYG TPFY+E LV+TYGKIM+H++ FP D VSE AKDLIR+LICS + R
Sbjct: 61 CMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTD--VSENAKDLIRRLICSREHR 118
Query: 3771 FGRNGLSDFQLHPFFEGIDWNTIRDSNPPYVPEVSSPEDTSNFDVDVCEDDFTPCLQ--E 3598
G+NG+ DF+ HPFF GIDW+ IR+ PY+PEVSSP DTSNFDVD DD CL+ E
Sbjct: 119 LGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIPEVSSPTDTSNFDVD---DD---CLKNSE 172
Query: 3597 TQPPRVLAAFTGNHLPFVGFSYTHGSLLSDARSL-------TDEIRAIAQRCQGDAELME 3439
T PP AF+G+HLPFVGF+YT +LSD L + ++ QR D L
Sbjct: 173 TMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTAGPTSLDLDVSVQRTL-DNNLAT 231
Query: 3438 KSVDGFMVELENEKAELVQKLKEA-QTIIA-QHVAENPRSEEDRNYESTIAQLKDEIQIL 3265
++ + + LE EK EL +KL+E+ QT+ A Q+ + ++ E I LK+EI+ L
Sbjct: 232 EAYERRIKRLEQEKLELTRKLQESTQTVQALQYSTVDGPLTASKDLE--IKSLKEEIEKL 289
Query: 3264 NKRLEDEALAQQQQKPKDEIVAXXXXXXXXXXERNKQ---LVMEKSEIQRELDN------ 3112
K++ + +QQ + + + KQ L E+ E+ +EL
Sbjct: 290 RKQVAEVNHLEQQLEEANSVRRELDDAFRQIKASEKQIKTLQQEREELNKELVQASERLK 349
Query: 3111 ----------------------INDHLDQVLVEKAT--------------VVQQRDDMQA 3040
IN+ L ++ +K V+Q+ + ++
Sbjct: 350 NQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKAESLRQ 409
Query: 3039 ELADVG----------DSLLTEKDSVKRLQDEAEKAKKQVADFXXXXXXXXXXXXX---X 2899
EL ++L+ E K+L++++E KQ+ +
Sbjct: 410 ELRRAERAKKELEVHTEALIAEASKDKKLREQSEHYSKQLENELEGLKQKQISYSPGICS 469
Query: 2898 XXKQEEVTIEARKSVETDDHLSEEVVAAKNTIASLQATNEERET------------EIKK 2755
Q+E+T + + +E EE ++ + I + + N ++E EI
Sbjct: 470 IEHQQEIT-KLKTDLEKKSIFYEEEISKREGIHASEIKNLKKELHDSEGQQLALNKEILV 528
Query: 2754 LKQRMDEERASHTAQSEQEMKQLEAHYERAQKMLQDN--------------VEQMNVENR 2617
LK ++++ R ++ E+ + + YER + +L + E +++ N+
Sbjct: 529 LKDKLEKTRRESQSEREEFENEFKQQYEREKVLLTEENKKLTSELDKLTSLYESLSLRNQ 588
Query: 2616 GLRDEIEKLSQQMAALPRGGLNEQQLHEIFNWVSEEKATREEMENLTRKITGEVESLKNN 2437
L +E++ L+ + ++ E Q+ EI WVS+EK R ++ L K+T E+E+L+N+
Sbjct: 589 HLEEEVKDLADKKESVAHW---EAQITEIIQWVSDEKDARGYLQALASKMTEELEALRNS 645
Query: 2436 SPLTTSNYIQNTPSGWGSRRMNNVARKDGLDLQRQLQAEIDAKLKLKAELKNSQEQYLTS 2257
S T + T W RR + L+LQ L AEI AK ++ EL + + +
Sbjct: 646 SLGTRA-----TDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEELNKVKASNILT 700
Query: 2256 AARLDDTEKRMASLMREVAMLKQQKNIENSSDSAFSSTMGRGDLMISMNNDYEMSNSSLM 2077
+L D+EK+ L+ E+ L + E S+ + + +N
Sbjct: 701 ECKLKDSEKKNLELLSEIEQLIKDTE-ELRSEKGIEHQDSQHSFLAFLNTP--------- 750
Query: 2076 RQEMISRQSTPSYENAILLHDHQVPKRVDDLRYKQKPMKTASGIFSPVSISAMERGHNFE 1897
T + + + +P LR K P T F P + H F
Sbjct: 751 ---------TDALDQFEIADCAPLPAHTPTLRKKGCPASTG---FPP-----KRKTHQFF 793
Query: 1896 RMKIKTPTKCGHCTSILIGLDRQGLFCQSCQYACHVSCAERVSQSCPVPEEERR-PLGID 1720
PTKC CTS+++GL RQG C+ C ++CH++C + CPVP E+ + PLGID
Sbjct: 794 VKSFTAPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTVCPVPPEQTKGPLGID 853
Query: 1719 PTRGVGTAYEGLVKTPRAGGVRKGWQTAYVVVCDFKLYLYDCTVDRQNKMQDVKNEIRLV 1540
P +GVGTAYEG V+ P+ GV+KGWQ A VVCDFKL+LYD + K + I V
Sbjct: 854 PQKGVGTAYEGHVRIPKPAGVKKGWQRALAVVCDFKLFLYDIA---EGKASQPTSVISQV 910
Query: 1539 LDMRDPDFTVCGVSEADVIHAQKGDIPKIFRVTTTQILNXXXXXXXXSKFYTLFMAETEE 1360
+DMRD +F+V V +DVIHA + DIP IFRVT +Q+ +K L +A++E
Sbjct: 911 IDMRDEEFSVSSVLASDVIHASRKDIPCIFRVTASQL------SAPSNKCSILMLADSEN 964
Query: 1359 EKRKWVVALSELKTLLRRSKLADRKAFLVKEVFDVTTLPSIRVAQCCAIIDRSKIVIGFS 1180
E+ KWV LSEL +L+++K DR ++ KE +D +TLP I+ Q AIID +I +G +
Sbjct: 965 ERSKWVGVLSELHKILKKNKFRDRSVYVPKEAYD-STLPLIKTTQAAAIIDHERIALG-N 1022
Query: 1179 DHGLYCIEISRQLLIPVGGEKENKQRCVETVEYDEAEQLLMMIVGPAKDRHVRIVPSAAL 1000
+ GL+ + +++ ++ VG K+ + +E ++QL+ +I G ++RHVR+ P +AL
Sbjct: 1023 EEGLFVVHVTKDEIVRVGDNKK-----IHQIELIPSDQLVAVISG--RNRHVRLFPMSAL 1075
Query: 999 DGRDLKWIKVNDTKGCHLLAVGTNNPGGRAGFFAVAFKKSVTIFQIDRSEKRHKKWKDLA 820
DGR+ + K+ +TKGC +A G G + VA K+ V +++ +S+ RH+K+K++
Sbjct: 1076 DGRETDFYKLAETKGCQTIAAGKVRHGALS-CLCVAMKRQVLCYELFQSKTRHRKFKEIQ 1134
Query: 819 MPGTPQSIAIFNGRLYVGFSHSFRSWSLVGVDSSPVGSGDASGAVLQHISLVNMEDTSLQ 640
+P Q +AIF+ L VGF F + L G + P ++++ D +L
Sbjct: 1135 VPCNVQWMAIFSEHLCVGFQSGFLRYPLNG-EGGPC-------------NMLHSNDHTLS 1180
Query: 639 FLNQQTSYEAKLIVNVPGSPDEYLLVFNMIGLYVNEMGRRSRLPEVMFPTQAKYFAYHEP 460
F++ Q +A V + S EYLL FN IG+Y + GRRSR E+M+P Y+ P
Sbjct: 1181 FISHQPM-DALCAVEI--SNKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPSSCCYNAP 1237
Query: 459 YLCVFSENEVDIFNVTLAEWVQTINLRSAKPLSGDGILSTCLCNDSPIFVLLQNVLQDQD 280
YL V+SEN VDIF+V EW+QT+ L+ +PL+ +G L+ L ++ + +N + + D
Sbjct: 1238 YLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNTEGSLN-LLGLETIRLIYFKNKMAEGD 1296
Query: 279 SIEVPVNLASGSTDGXXXXXXXXXXXTIGKDDRSASERRSHIQ--------ISTPSDFMH 124
+ VP + ++ +RR ++ IS P++F H
Sbjct: 1297 ELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISNPTNFNH 1356
Query: 123 IVHMGPAPVMEL 88
I HMGP +++
Sbjct: 1357 IAHMGPGDGIQI 1368
>gi|48103540|ref|XP_395596.1| similar to ENSANGP00000009214 [Apis
mellifera]
Length = 1864
Score = 676 bits (1743), Expect = 0.0
Identities = 411/1005 (40%), Positives = 575/1005 (56%), Gaps = 104/1005 (10%)
Frame = -1
Query: 4773 EPPPD--------DSAPVRLKTLENIYMDGP----SKKPEALSFETLIDSLICLYDECCN 4630
+PPPD + RL+ LE++++ GP + S ETLID L+ LYDECCN
Sbjct: 11 QPPPDIMPKGLAINGIGGRLRQLESLFIGGPVQGEGRIGHTFSIETLIDILLVLYDECCN 70
Query: 4629 STLRKEKCIAEFVESVKTVISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYA 4450
S+LR+EK +++F+E VK V + K L+L+R+DFE++KVIG+GAFGEV VVRMRG +++A
Sbjct: 71 SSLRREKTVSDFIEFVKPVATCIKSLQLAREDFEIVKVIGRGAFGEVCVVRMRGSDKVFA 130
Query: 4449 MKILNKWEMVKRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLT 4270
MKILNKWEM+KRAETA FREERDVLVYGDRRWITNLHYAFQD+ NLY VMDYY GGD+LT
Sbjct: 131 MKILNKWEMLKRAETAYFREERDVLVYGDRRWITNLHYAFQDDNNLYLVMDYYCGGDLLT 190
Query: 4269 LLSKFVDHIPESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCL 4090
LLSKF D +PE MA+FYIAEMVLAI S+H L YVHRD+KPDNVLLD GHIRLADFGSCL
Sbjct: 191 LLSKFEDRLPEDMARFYIAEMVLAIGSIHDLRYVHRDIKPDNVLLDANGHIRLADFGSCL 250
Query: 4089 RILADGSVASNVAVGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYS 3910
R+ DG+ SNVAVGTPDYISPEILRAMEDG+G+YG ECDWWSLG+CMYEMLYG TPFY+
Sbjct: 251 RLFEDGTAQSNVAVGTPDYISPEILRAMEDGQGQYGPECDWWSLGVCMYEMLYGETPFYA 310
Query: 3909 ERLVDTYGKIMSHQDMLDFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPF 3730
E LV+TYGKIM+H++ DFP D+I + VSEEAKDL+R+LICSS+ R G+NG+ DF+ HP+
Sbjct: 311 ESLVETYGKIMNHKNCFDFPADDI-YEVSEEAKDLMRKLICSSEFRLGQNGIDDFKKHPW 369
Query: 3729 FEGIDWNTIRDSNPPYVPEVSSPEDTSNFDVDVCEDDFTPCLQETQPPRVLAAFTGNHLP 3550
FEG++W+T+RDS PY+PEVSSP DTSNFDV DD + PP +AF+ HLP
Sbjct: 370 FEGVNWDTLRDSTAPYIPEVSSPTDTSNFDV----DDTDVRSSDAVPPAANSAFSALHLP 425
Query: 3549 FVGFSYTHGSLLSDARSLTDEIRAIAQRCQGDAELMEKSVDGFMVELENEKAELVQKLKE 3370
FVGF++T GS +SD L+ AI Q+ D M LE E A+L+Q L +
Sbjct: 426 FVGFTFTQGSCISDLGCLS----AITQK------------DKRMQMLEEENAQLIQTLDD 469
Query: 3369 AQTIIAQHVAENPRSEEDRNYESTIAQLKDEIQILNKR---------------------- 3256
+ I + +P D N + +L+DEI L KR
Sbjct: 470 LKKQINMN-HSSPGISPDSN--NATRKLQDEINTLTKRNCELESQLKSMEIPRELRNLDN 526
Query: 3255 ------LEDEALAQQQQKPKDEIVAXXXXXXXXXXERNKQL---VMEKSEIQRELDNIND 3103
E E L + + K+E + ++K+L + ++ E + D
Sbjct: 527 GDITKLRELEKLVRSLRLEKEEAIKDKLDAQEKLKLQDKELKDALTQRKLAMAEYTEVTD 586
Query: 3102 HLDQVLVEKATVVQQRDDMQAELADV---GDSL---------------------LTEKDS 2995
L ++ +K + +Q D + EL V DSL + E
Sbjct: 587 KLSELRQQKQKLSRQVRDKEEELEVVMQKVDSLRHDIRKAEKLRRELENRVEEAMAETSK 646
Query: 2994 VKRLQDEAEKAKKQVAD----FXXXXXXXXXXXXXXXXKQEEVTIEA---RKSVETDDHL 2836
++L++ +E+ KQ+ + QE ++A + V+ +++L
Sbjct: 647 ERKLRERSEEYCKQMQEETEKIRQRSIGNDAGANHALATQEINRLKAEVEKLEVQYNENL 706
Query: 2835 SEEVVAAKNTIASLQATNEERET-------EIKKLKQRMDEERASHTAQSEQEMKQLEAH 2677
+++ I SLQ E ET E++ K+++D R + SE+ + +L
Sbjct: 707 NQQQSRFNLEIRSLQEQLHETETRRDLLEREVQLTKEKLDTARLENITDSEETINELNRR 766
Query: 2676 YERAQKM--------------LQDNVEQMNVENRGLRDEIEKLSQQMAALPRGGLNEQQL 2539
+ER + M L D+V ++ E R L +E E+L + A+ + E Q+
Sbjct: 767 HEREKIMLVEENKKLMLELNTLTDSVNRIQGERRQLEEEYEELRNKKEAIAQW---EAQI 823
Query: 2538 HEIFNWVSEEKATREEMENLTRKITGEVESLKNNSPL-TTSNYIQNTPSGWGSRRMNNVA 2362
EI WVS+EK R ++ L K+T E+E LK++ + + W +RR +
Sbjct: 824 TEIIQWVSDEKDARGYLQALATKMTEELEFLKHSGGVGGVGSGSTMADKNWRNRRSQKLD 883
Query: 2361 RKDGLDLQRQLQAEIDAKLKLKAELKNSQEQYLTSAARLDDTEKRMASLMREVAMLKQQ- 2185
+ + L+LQ LQ+EI AK + EL ++ + + L D +R +L E+ + Q
Sbjct: 884 KMELLNLQSSLQSEIQAKQAISEELTKTRSDLIAAQKELRDFRQRFDTLTHEIKRKEMQI 943
Query: 2184 KNIENSSDS-------AFSSTMGRGDLMISMNNDYEMSNSSLMRQ 2071
K ++ D+ +F++ L I + Y+ S S+++ Q
Sbjct: 944 KELQARLDTGDGCKYISFNTVTKTNFLKILLLRFYKNSVSTIIIQ 988
Score = 420 bits (1079), Expect = e-115
Identities = 255/648 (39%), Positives = 374/648 (57%), Gaps = 15/648 (2%)
Frame = -1
Query: 1914 RGHNFERMKIKTPTKCGHCTSILIGLDRQGLFCQSCQYACHVSCAERVSQSCPVPEEE-R 1738
+ H F TPTKC HCTS+++GL RQG+ C+ C +ACH+ C ++V CPVP ++ +
Sbjct: 1171 KSHQFLVRTFSTPTKCNHCTSLMVGLTRQGVVCEVCGFACHMPCCDKVPPMCPVPHDQTK 1230
Query: 1737 RPLGIDPTRGVGTAYEGLVKTPRAGGVRKGWQTAYVVVCDFKLYLYDCTVDRQNKMQDVK 1558
RPLGIDPTRG+GTAYEG VK P+ GGV+KGW +VVVCDFKL+LYD + DR N + V
Sbjct: 1231 RPLGIDPTRGIGTAYEGYVKVPKMGGVKKGWVRQFVVVCDFKLFLYDISPDR-NALPSVY 1289
Query: 1557 NEIRLVLDMRDPDFTVCGVSEADVIHAQKGDIPKIFRVTTTQILNXXXXXXXXSKFYTLF 1378
+ VLDMRD +F+V V ++DVIHA K DIP IFR+TT+ + + +TL
Sbjct: 1290 --VSQVLDMRDEEFSVSSVRDSDVIHATKKDIPCIFRITTSLL------EPPGLRNHTLM 1341
Query: 1377 MAETEEEKRKWVVALSELKTLLRRSKLADRKAFLVKEVFDVTTLPSIRVAQCCAIIDRSK 1198
+A+TE EK KWVVALSEL +L+++ L + F KE+ D TL I+ AIID +
Sbjct: 1342 LADTESEKTKWVVALSELHRILKKNNLPNTTIFRAKELLD-NTLALIKNVMSGAIIDPDR 1400
Query: 1197 IVIGFSDHGLYCIEISRQLLIPVGGEKENKQRCVETVEYDEAEQLLMMIVGPAKDRHVRI 1018
+VIG ++ GL+C+++ R + VG K+ + +EY EQL++++ G K RHVR+
Sbjct: 1401 LVIG-TEEGLFCLDLDRSEIARVGEGKK-----IYLLEYVTEEQLIVVLSG--KQRHVRL 1452
Query: 1017 VPSAALDGRDLKWIKVNDTKGCHLLAVGTNNPGGRAGFFAVAFKKSVT----IFQIDRSE 850
VP ALDG +++WIKV +TKGC L G VA KK T I++I R++
Sbjct: 1453 VPVRALDGDEVEWIKVAETKGCITLTTGIVRRSPLTYCLCVAIKKQNTSQIIIYEITRTK 1512
Query: 849 KRHKKWKDLAMPGTPQSIAIFN-GRLYVGFSHSFRSWSLVGVDSSPVGSGDASGAVLQHI 673
RHK+ ++L + Q++ I + GR VG+ F +S++G D P I
Sbjct: 1513 TRHKRIRELMLSCHAQTLQILSEGRFCVGYPSGFSIYSILG-DHHP-------------I 1558
Query: 672 SLVNMEDTSLQFLNQQTSYEAKLIVNVPGSPDEYLLVFNMIGLYVNEMGRRSRLPEVMFP 493
SLV+ E+T L FL ++ +A + +P E+LLVF+ + +YV+ GR+SR E+M+P
Sbjct: 1559 SLVHSENTLLGFLTY-SAVDALRCIELPRG--EFLLVFHTLAVYVDSQGRKSRDREIMYP 1615
Query: 492 TQAKYFAYHEPYLCVFSENEVDIFNVTLAEWVQTINLRSAKPLSGDGILSTCLCNDSPIF 313
+Y E YL V+SE +D+F+ T +W+QT+N++ A+PL+ G L++C+ ND P
Sbjct: 1616 AVPTAVSYCEGYLLVYSETHIDVFDCTTGDWLQTLNVKRARPLNTSGSLTSCIINDMPHV 1675
Query: 312 VLLQNVLQDQDSIEVPVNLASGSTDGXXXXX-XXXXXXTIGKDDRSASERRSHIQISTPS 136
+ L N+ Q + +NL G G ++RRS + IS P+
Sbjct: 1676 IFLSNLHQRE-----LLNLTPLDPSGRQMTKPRRRFSLREGNRAIRPTDRRSKM-ISAPT 1729
Query: 135 DFMHIVHMGPAPVMELQQ--------NFIDLQSNHSHTSSDKDSLNRS 16
+F HI HMGP +++Q+ D Q H+SS S S
Sbjct: 1730 NFNHISHMGPGNGIQIQRLLDLPTTLETADQQHTGHHSSSHLHSSTSS 1777
>gi|28839596|gb|AAH47871.1| CDC42BPB protein [Homo sapiens]
Length = 933
Score = 655 bits (1689), Expect = 0.0
Identities = 388/947 (40%), Positives = 555/947 (57%), Gaps = 89/947 (9%)
Frame = -1
Query: 4755 SAPVRLKTLENIYMDGPSKKPEALSFETLIDSLICLYDECCNSTLRKEKCIAEFVESVKT 4576
SA VRLK LE + +DGP + ALS ETL+D L+CLY EC +S LR++K +AEF+E K
Sbjct: 2 SAKVRLKKLEQLLLDGPWRNESALSVETLLDVLVCLYTECSHSALRRDKYVAEFLEWAKP 61
Query: 4575 VISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACF 4396
K+++L R+DFE++KVIG+GAFGEVAVV+M+ IYAMKILNKWEM+KRAETACF
Sbjct: 62 FTQLVKEMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACF 121
Query: 4395 REERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFYI 4216
REERDVLV GD +WIT LHYAFQDE +LY VMDYY+GGD+LTLLSKF D +PE MA+FYI
Sbjct: 122 REERDVLVNGDCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYI 181
Query: 4215 AEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASNVAVGTPD 4036
EMVLAIDS+H+L YVHRD+KPDNVLLD+ GHIRLADFGSCL++ DG+V S+VAVGTPD
Sbjct: 182 GEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPD 241
Query: 4035 YISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDMLD 3856
YISPEIL+AMEDG G+YG ECDWWSLG+CMYEMLYG TPFY+E LV+TYGKIM+H++
Sbjct: 242 YISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQ 301
Query: 3855 FPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIRDSNPPYVP 3676
FP D VSEEAKDLI++LICS + R G+NG+ DF+ H FFEG++W IR+ PY+P
Sbjct: 302 FPSHVTD--VSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIP 359
Query: 3675 EVSSPEDTSNFDVDVCEDDFTPCLQETQ--PPRVLAAFTGNHLPFVGFSYTHGSLLSDAR 3502
+VSSP DTSNFDVD DD L+ T+ PP F+G HLPF+GF++T S SD
Sbjct: 360 DVSSPSDTSNFDVD---DD---VLRNTEILPPGSHTGFSGLHLPFIGFTFTTESCFSDRG 413
Query: 3501 SLTDEIRAIA----QRCQGDAE--LMEKSVDGFMVELENEKAELVQKLKEA-QTIIAQH- 3346
SL +++ + Q D E L ++ + + LE EK EL +KL+E+ QT+ + H
Sbjct: 414 SLKSIMQSNTLTKDEDVQRDLEHSLQMEAYERRIRRLEQEKLELSRKLQESTQTVQSLHG 473
Query: 3345 ----VAENPRSEEDRNYESTIAQLKDEI---QILNKRLEDEALAQQQ------------- 3226
++ + R +E + I +LK++I L ++LED +Q+
Sbjct: 474 SSRALSNSNRDKEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEK 533
Query: 3225 -----QKPKDEIVAXXXXXXXXXXERNKQLV---MEKSEIQRELDNINDHLDQVLVEKAT 3070
++ K+E+ + K+L ++ +E +N+ + ++ +K
Sbjct: 534 QHRVVRQEKEELHKQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQK 593
Query: 3069 VVQQRDD------------------------MQAELADVGDSLLTEKDSVKRLQDEAEKA 2962
V +Q D ++ EL D + E ++L++ +E
Sbjct: 594 VSRQLRDKEEEMEVATQKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERKLREHSENF 653
Query: 2961 KKQVADFXXXXXXXXXXXXXXXXKQEEVTIEARKS-VETDDHLSEEVVAAKNTIASLQAT 2785
KQ+ + + I KS +E EE + + L+
Sbjct: 654 CKQMESELEALKVKQGGRGAGATLEHQQEISKIKSELEKKVLFYEEELVRREASHVLEVK 713
Query: 2784 NEERET------------EIKKLKQRMDEERASHTAQSEQEMKQLEAHYERAQKMLQDN- 2644
N ++E EI LK ++++ + + E+ + ++ YER + ML D
Sbjct: 714 NVKKEVHDSESHQLALQKEILMLKDKLEKSKRERHNEMEEAVGTIKDKYERERAMLFDEN 773
Query: 2643 -------------VEQMNVENRGLRDEIEKLSQQMAALPRGGLNEQQLHEIFNWVSEEKA 2503
V+++ +NR L DE++ L+ + ++ E Q+ EI WVS+EK
Sbjct: 774 KKLTAENEKLCSFVDKLTAQNRQLEDELQDLAAKKESVAHW---EAQIAEIIQWVSDEKD 830
Query: 2502 TREEMENLTRKITGEVESLKNNSPLTTSNYIQNTPSGWGSRRMNNVARKDGLDLQRQLQA 2323
R ++ L K+T E+E+L+++S + + W RR + L+LQ L+A
Sbjct: 831 ARGYLQALASKMTEELEALRSSSLGS-----RTLDPLWKVRRSQKLDMSARLELQSALEA 885
Query: 2322 EIDAKLKLKAELKNSQEQYLTSAARLDDTEKRMASLMREVAMLKQQK 2182
EI AK ++ EL+ ++ LT ++L D+E + L+ E+ +LK++K
Sbjct: 886 EIRAKQLVQEELRKVKDANLTLESKLKDSEAKNRELLEEMEILKKKK 932