Homology by BLASTX
BLASTX 2.2.4 [Aug-26-2002]
Query= K10B3_6
(7284 letters)
Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
1,967,186 sequences; 661,712,633 total letters
Score E
Sequences producing significant alignments: (bits) Value
gi|17569483|ref|NP_508537.1| spectrin (spc-1) [Caenorhabditis el... 4681 0.0
gi|39597692|emb|CAE68383.1| Hypothetical protein CBG14139 [Caeno... 4576 0.0
gi|31218879|ref|XP_316724.1| ENSANGP00000002653 [Anopheles gambi... 3031 0.0
gi|17136504|ref|NP_476739.1| CG1977-PA [Drosophila melanogaster]... 3030 0.0
gi|103399|pir||A33733 spectrin alpha chain - fruit fly (Drosophi... 3028 0.0
gi|47477769|gb|AAH70885.1| Spna2 protein [Rattus norvegicus] 2854 0.0
gi|31565122|gb|AAH53521.1| SPTAN1 protein [Homo sapiens] 2848 0.0
gi|17380501|sp|P16086|SPCN_RAT Spectrin alpha chain, brain (Spec... 2845 0.0
gi|31543764|ref|NP_741984.2| alpha-spectrin 2; alpha-fodrin; noe... 2838 0.0
gi|50757376|ref|XP_415495.1| PREDICTED: similar to spectrin alph... 2836 0.0
gi|134800|sp|P07751|SPCN_CHICK Spectrin alpha chain, brain (Spec... 2832 0.0
gi|1805280|gb|AAB41498.1| alpha II spectrin [Homo sapiens] 2830 0.0
gi|4507191|ref|NP_003118.1| spectrin, alpha, non-erythrocytic 1 ... 2821 0.0
gi|1334744|emb|CAA32663.1| spectrin alpha chain [Gallus gallus] 2806 0.0
gi|34852958|ref|XP_346648.1| hypothetical protein XP_346647 [Rat... 2640 0.0
gi|38074607|ref|XP_207079.2| spectrin alpha 2 [Mus musculus] 2144 0.0
gi|47211130|emb|CAF90368.1| unnamed protein product [Tetraodon n... 2141 0.0
gi|1174412|sp|P02549|SPCA_HUMAN Spectrin alpha chain, erythrocyt... 2004 0.0
gi|4507189|ref|NP_003117.1| spectrin, alpha, erythrocytic 1 (ell... 2001 0.0
gi|19526481|ref|NP_035595.2| spectrin alpha 1; alpha-spectrin 1,... 1996 0.0
gi|17380523|sp|P08032|SPCA_MOUSE Spectrin alpha chain, erythrocy... 1993 0.0
gi|33303718|gb|AAQ02378.1| erythroid spectrin alpha [Rattus norv... 1919 0.0
gi|34880958|ref|XP_222913.2| similar to erythroid alpha-spectrin... 1893 0.0
gi|46577681|sp|P16546|SPCN_MOUSE Spectrin alpha chain, brain (Sp... 1727 0.0
gi|20380003|gb|AAH27791.1| Spna2 protein [Mus musculus] 1618 0.0
gi|7512790|pir||T14790 hypothetical protein DKFZp564P0562.1 - hu... 1536 0.0
gi|92758|pir||A32612 spectrin alpha chain, nonerythroid - rat (f... 1220 0.0
gi|17862818|gb|AAL39886.1| LP06350p [Drosophila melanogaster] 1115 0.0
gi|178426|gb|AAA51702.1| alpha-fodrin >gnl|BL_ORD_ID|114424 gi|5... 1031 0.0
gi|47211129|emb|CAF90367.1| unnamed protein product [Tetraodon n... 921 0.0
gi|7441355|pir||S61217 spectrin alpha II chain - rat (fragment) 883 0.0
gi|12847774|dbj|BAB27703.1| unnamed protein product [Mus musculus] 802 0.0
gi|836669|gb|AAB60364.1| alpha II spectrin [Homo sapiens] 774 0.0
gi|31209523|ref|XP_313728.1| ENSANGP00000017034 [Anopheles gambi... 766 0.0
gi|161334|gb|AAA30008.1| alpha-spectrin 759 0.0
gi|45552921|ref|NP_995987.1| CG12008-PC [Drosophila melanogaster... 756 0.0
gi|45552923|ref|NP_995988.1| CG12008-PB [Drosophila melanogaster... 756 0.0
gi|24656802|ref|NP_523900.1| CG12008-PA [Drosophila melanogaster... 756 0.0
gi|38075498|ref|XP_359378.1| similar to Spectrin alpha chain, br... 709 0.0
gi|38051869|gb|AAH60504.1| Spna2 protein [Mus musculus] 665 0.0
gi|39592126|emb|CAE75346.1| Hypothetical protein CBG23326 [Caeno... 662 0.0
gi|38074605|ref|XP_355324.1| similar to Spectrin alpha chain, br... 652 0.0
gi|7506776|pir||T23630 hypothetical protein R31.1 - Caenorhabdit... 652 0.0
gi|50748191|ref|XP_421149.1| PREDICTED: similar to Spectrin beta... 652 0.0
gi|25155104|ref|NP_741632.1| SMAll body size SMA-1, betaH chain ... 652 0.0
gi|5902122|ref|NP_008877.1| spectrin, beta, non-erythrocytic 2 [... 598 e-169
gi|7106421|ref|NP_033286.1| spectrin beta 2 isoform 2; beta-spec... 592 e-167
gi|34879632|ref|XP_240072.2| similar to Spectrin beta chain, bra... 581 e-164
gi|50738496|ref|XP_419291.1| PREDICTED: similar to Spectrin beta... 578 e-163
gi|48136657|ref|XP_396777.1| similar to ENSANGP00000017034 [Apis... 574 e-161
gi|47227240|emb|CAG00602.1| unnamed protein product [Tetraodon n... 573 e-161
gi|7706190|ref|NP_057726.1| spectrin, beta, non-erythrocytic 5; ... 568 e-160
gi|448251|prf||1916380A beta spectrin (beta fodrin) 567 e-159
gi|4507195|ref|NP_003119.1| spectrin, beta, non-erythrocytic 1 i... 560 e-157
gi|30315658|ref|NP_842565.1| spectrin, beta, non-erythrocytic 1 ... 560 e-157
gi|30348966|ref|NP_787030.1| spectrin beta 2 isoform 1; beta-spe... 559 e-157
gi|85771|pir||S01092 fodrin alpha chain (clone alpha-2) - Africa... 555 e-156
gi|15213122|gb|AAK85734.1| beta-G spectrin [Brugia malayi] 544 e-152
gi|48101779|ref|XP_395212.1| similar to ENSANGP00000012507 [Apis... 541 e-152
gi|33303722|gb|AAQ02380.1| non-erythroid spectrin beta [Rattus n... 540 e-151
gi|88622|pir||B27671 spectrin alpha chain, nonerythroid - human ... 539 e-151
gi|189071|gb|AAA59904.1| alpha-spectrin 537 e-150
gi|92757|pir||A27671 spectrin alpha chain, nonerythroid - rat (f... 537 e-150
gi|17647191|ref|NP_523388.1| CG5870-PA [Drosophila melanogaster]... 537 e-150
gi|423777|pir||A46147 spectrin beta chain - fruit fly (Drosophil... 537 e-150
gi|39594389|emb|CAE71967.1| Hypothetical protein CBG19038 [Caeno... 536 e-150
gi|7505762|pir||T29140 hypothetical protein K11C4.3 - Caenorhabd... 535 e-150
gi|17976528|gb|AAK77612.2| Uncoordinated protein 70, isoform b [... 535 e-150
gi|5734146|gb|AAD49858.1| beta-G spectrin [Caenorhabditis elegans] 535 e-150
gi|17562506|ref|NP_504748.1| beta-G spectrin, UNCoordinated loco... 535 e-150
gi|25154697|ref|NP_504749.2| beta-G spectrin, UNCoordinated loco... 535 e-150
gi|2119257|pir||I50420 nonerythroid alpha-spectrin - chicken (fr... 532 e-149
gi|829111|emb|CAA60503.1| alpha-spectrin [Homo sapiens] 531 e-148
gi|31201697|ref|XP_309796.1| ENSANGP00000012507 [Anopheles gambi... 528 e-148
gi|31201699|ref|XP_309797.1| ENSANGP00000023406 [Anopheles gambi... 528 e-148
gi|27413156|ref|NP_000338.2| spectrin, beta, erythrocytic (inclu... 523 e-146
gi|338440|gb|AAA60578.1| spectrin Rouen (beta-220-218) mutant co... 523 e-146
gi|134798|sp|P11277|SPCB_HUMAN Spectrin beta chain, erythrocyte ... 523 e-146
gi|11066461|gb|AAG28596.1| spectrin-like protein GTRAP41 [Rattus... 520 e-145
gi|103502|pir||A37792 spectrin beta-H chain - fruit fly (Drosoph... 516 e-144
gi|5640028|emb|CAB51571.1| putative alpha-spectrin [Gallus gallus] 516 e-144
gi|7655|emb|CAA37939.1| betaH spectrin [Drosophila melanogaster] 515 e-144
gi|50300486|ref|NP_038703.2| spectrin beta 1; beta-spectrin 1; s... 507 e-141
gi|11992162|gb|AAG42473.1| spectrin beta IV [Homo sapiens] 506 e-141
gi|17368942|sp|Q9H254|SPCQ_HUMAN Spectrin beta chain, brain 3 (S... 506 e-141
gi|10047361|dbj|BAB13468.1| KIAA1642 protein [Homo sapiens] 506 e-141
gi|11602890|gb|AAF93173.1| betaIV spectrin isoform sigma4 [Homo ... 505 e-141
gi|13435161|ref|NP_079489.1| spectrin, beta, non-erythrocytic 4 ... 504 e-141
gi|47058982|ref|NP_997687.1| erythroid spectrin beta [Rattus nor... 504 e-140
gi|30794220|ref|NP_115999.1| spectrin beta 4; beta-spectrin 4; q... 500 e-139
gi|34866100|ref|XP_234322.2| similar to Spectrin beta chain, ery... 499 e-139
gi|16117405|gb|AAK38731.1| beta4-spectrin [Mus musculus] >gnl|BL... 499 e-139
gi|18859423|ref|NP_571600.1| spectrin, beta, erythrocytic; beta-... 498 e-139
gi|34855389|ref|XP_218364.2| similar to betaIV-spectrin sigma1 [... 497 e-138
gi|40353204|ref|NP_066022.1| spectrin, beta, non-erythrocytic 4 ... 496 e-138
gi|476928|pir||A47213 beta-fodrin - human (fragment) >gnl|BL_ORD... 495 e-138
gi|21429122|gb|AAM50280.1| LP04011p [Drosophila melanogaster] 493 e-137
gi|47209542|emb|CAF96656.1| unnamed protein product [Tetraodon n... 488 e-136
gi|2506246|sp|P15508|SPCB_MOUSE Spectrin beta chain, erythrocyte... 486 e-135
gi|47210379|emb|CAF95574.1| unnamed protein product [Tetraodon n... 482 e-134
gi|38075670|ref|XP_141326.3| similar to Spectrin beta chain, bra... 481 e-133
gi|50510447|dbj|BAD32209.1| mKIAA0302 protein [Mus musculus] 479 e-133
gi|38084794|ref|XP_129130.3| spectrin beta 3 [Mus musculus] 479 e-133
gi|17367415|sp|Q9QWN8|SPCP_RAT Spectrin beta chain, brain 2 (Spe... 465 e-129
gi|9507135|ref|NP_062040.1| beta-spectrin 3 [Rattus norvegicus] ... 461 e-127
gi|34856723|ref|XP_238278.2| similar to Spectrin beta chain, bra... 452 e-125
gi|2655084|gb|AAB87867.1| beta-H spectrin [Drosophila melanogaster] 445 e-123
gi|338409|gb|AAA60575.1| alpha-I spectrin 431 e-118
gi|33340563|gb|AAQ14859.1| beta spectrin IV [Homo sapiens] 428 e-118
gi|6446579|gb|AAA21249.2| beta-heavy-spectrin [Drosophila melano... 405 e-111
gi|109842|pir||A43769 fodrin alpha chain - mouse (fragment) 394 e-107
gi|930145|emb|CAA31289.1| alpha-fodrin (382 AA) [Mus musculus] 394 e-107
gi|47221201|emb|CAG13137.1| unnamed protein product [Tetraodon n... 389 e-106
gi|85770|pir||S01091 fodrin alpha chain (clone alpha-1) - Africa... 383 e-104
gi|40216167|gb|AAR82828.1| AT24411p [Drosophila melanogaster] 375 e-102
gi|29893185|gb|AAP03079.1| antigen [Taenia cellulosae] 372 e-101
gi|47221024|emb|CAG12718.1| unnamed protein product [Tetraodon n... 367 2e-99
gi|26351911|dbj|BAC39592.1| unnamed protein product [Mus musculus] 349 7e-94
gi|338330|gb|AAA63259.1| muscle beta spectrin 338 1e-90
gi|544668|gb|AAB29442.1| alpha-spectrin [Drosophila melanogaster] 336 6e-90
gi|47124694|gb|AAH70594.1| MGC81191 protein [Xenopus laevis] 311 2e-82
gi|32449722|gb|AAH43995.2| ACTN1 protein [Xenopus laevis] 307 2e-81
gi|13124665|sp|P05094|AAC1_CHICK Alpha-actinin 1 (Alpha-actinin ... 306 4e-81
gi|539494|pir||A42162 alpha-actinin 1 - chicken >gnl|BL_ORD_ID|5... 306 4e-81
gi|63389|emb|CAA32079.1| fibroblast alpha actinin [Gallus gallus] 306 6e-81
gi|18147604|dbj|BAB83244.1| betaIV-spectrin sigma6-A [Mus muscul... 305 1e-80
gi|13591902|ref|NP_112267.1| actinin, alpha 1; non-muscle alpha-... 304 2e-80
gi|4501891|ref|NP_001093.1| actinin, alpha 1 [Homo sapiens] >gnl... 303 4e-80
gi|30585329|gb|AAP36937.1| Homo sapiens actinin, alpha 1 [synthe... 303 4e-80
gi|45383852|ref|NP_989458.1| actinin, alpha 1 [Gallus gallus] >g... 303 5e-80
gi|47169151|pdb|1SJJ|A Chain A, Cryo-Em Structure Of Chicken Giz... 303 5e-80
gi|46395721|sp|Q7TPR4|AAC1_MOUSE Alpha-actinin 1 (Alpha-actinin ... 302 7e-80
gi|41054603|ref|NP_955880.1| actinin alpha 4; wu:fb53f05 [Danio ... 301 1e-79
gi|625303|pir||FAHUAA alpha-actinin 1 - human >gnl|BL_ORD_ID|674... 301 2e-79
gi|49256643|gb|AAH74001.1| Actn1 protein [Rattus norvegicus] 300 3e-79
gi|28723|emb|CAA38970.1| alpha-actinin [Homo sapiens] 299 6e-79
gi|38018016|gb|AAR08137.1| brain-specific alpha actinin 1 isofor... 295 1e-77
gi|31242389|ref|XP_321625.1| ENSANGP00000023605 [Anopheles gambi... 293 6e-77
gi|31242387|ref|XP_321624.1| ENSANGP00000011796 [Anopheles gambi... 293 6e-77
gi|24639238|ref|NP_477484.2| CG4376-PA [Drosophila melanogaster]... 290 3e-76
gi|24639240|ref|NP_726784.1| CG4376-PB [Drosophila melanogaster]... 290 3e-76
gi|13124689|sp|P18091|AACT_DROME Alpha-actinin, sarcomeric (F-ac... 290 3e-76
gi|17137758|ref|NP_477485.1| CG4376-PC [Drosophila melanogaster]... 290 3e-76
gi|39594084|emb|CAE70194.1| Hypothetical protein CBG16668 [Caeno... 290 4e-76
gi|34876265|ref|XP_214499.2| similar to actinin, alpha 2 [Rattus... 290 5e-76
gi|31981445|ref|NP_150371.2| actinin alpha 2 [Mus musculus] >gnl... 290 5e-76
gi|45384104|ref|NP_990457.1| alpha-actinin [Gallus gallus] >gnl|... 289 6e-76
gi|1070611|pir||FAFFAA alpha-actinin - fruit fly (Drosophila mel... 288 1e-75
gi|13123947|sp|Q9JI91|AAC2_MOUSE Alpha-actinin 2 (Alpha actinin ... 288 1e-75
gi|8186|emb|CAA36042.1| unnamed protein product [Drosophila mela... 288 2e-75
gi|11230802|ref|NP_068695.1| actinin alpha 4 [Mus musculus] >gnl... 287 2e-75
gi|4501893|ref|NP_001094.1| actinin, alpha 2 [Homo sapiens] >gnl... 287 3e-75
gi|2804273|dbj|BAA24447.1| alpha actinin 4 [Homo sapiens] 286 4e-75
gi|12025678|ref|NP_004915.2| actinin, alpha 4 [Homo sapiens] >gn... 286 4e-75
gi|33874637|gb|AAH15620.2| ACTN4 protein [Homo sapiens] 286 4e-75
gi|38197444|gb|AAH61788.1| Actn4 protein [Rattus norvegicus] 286 7e-75
gi|34855625|ref|XP_346542.1| hypothetical protein XP_346541 [Rat... 286 7e-75
gi|13123941|sp|Q9QXQ0|AAC4_RAT Alpha-actinin 4 (Non-muscle alpha... 284 2e-74
gi|13384169|gb|AAK21296.1| alpha actinin 4 [Rattus norvegicus] 284 2e-74
gi|50418010|gb|AAH77918.1| Unknown (protein for MGC:80841) [Xeno... 284 2e-74
gi|49903350|gb|AAH76687.1| Unknown (protein for MGC:79707) [Xeno... 282 8e-74
gi|45387533|ref|NP_991107.1| Unknown (protein for MGC:77243); wu... 281 2e-73
gi|25992501|gb|AAN77132.1| alpha-actinin [Danio rerio] >gnl|BL_O... 281 2e-73
gi|46048687|ref|NP_990654.1| alpha-actinin [Gallus gallus] >gnl|... 280 3e-73
gi|13928936|ref|NP_113863.1| alpha actinin 4; alpha actinin 4, b... 279 6e-73
gi|49903986|gb|AAH76640.1| Unknown (protein for MGC:78775) [Xeno... 278 1e-72
gi|47212235|emb|CAF96202.1| unnamed protein product [Tetraodon n... 278 1e-72
gi|50803149|ref|XP_424262.1| PREDICTED: similar to spectrin, bet... 275 9e-72
gi|47224786|emb|CAG06356.1| unnamed protein product [Tetraodon n... 275 2e-71
gi|50417651|gb|AAH77752.1| Unknown (protein for MGC:79035) [Xeno... 273 5e-71
gi|47939926|gb|AAH72105.1| MGC79034 protein [Xenopus laevis] >gn... 271 1e-70
gi|32766313|gb|AAH54911.1| Zgc:63559 protein [Danio rerio] 271 1e-70
gi|49899924|gb|AAH76938.1| Unknown (protein for MGC:89234) [Xeno... 270 3e-70
gi|37362178|gb|AAQ91217.1| actinin, alpha 2 [Danio rerio] 270 4e-70
gi|7304855|ref|NP_038484.1| actinin alpha 3 [Mus musculus] >gnl|... 268 2e-69
gi|19173800|ref|NP_596915.1| actinin alpha 3 [Rattus norvegicus]... 267 3e-69
gi|29179635|gb|AAH48851.1| Similar to beta-spectrin 3 [Mus muscu... 267 3e-69
gi|20853961|gb|AAM26632.1| truncated alpha-actinin [Rattus norve... 266 7e-69
gi|6716516|gb|AAF26672.1| nonerythroid alpha-spectrin [Homo sapi... 265 1e-68
gi|4557241|ref|NP_001095.1| skeletal muscle specific actinin, al... 261 1e-67
gi|48123513|ref|XP_393253.1| similar to Alpha-actinin, sarcomeri... 260 3e-67
gi|224115|prf||1010302A spectrin alpha fragment 259 9e-67
gi|13096866|gb|AAH03232.1| Actn1 protein [Mus musculus] 257 3e-66
gi|3157976|gb|AAC17470.1| alpha actinin [Homo sapiens] 250 3e-64
gi|444793|prf||1908227A beta spectrin 250 4e-64
gi|18481635|gb|AAL73492.1| beta I spectrin form betaI sigma3 [Ho... 249 5e-64
gi|420115|pir||S29854 spectrin beta chain - dog (fragment) >gnl|... 246 5e-63
gi|11992164|gb|AAG42474.1| spectrin beta IV [Homo sapiens] 244 3e-62
gi|47218151|emb|CAG10071.1| unnamed protein product [Tetraodon n... 233 4e-59
gi|39592275|emb|CAE75496.1| Hypothetical protein CBG23504 [Caeno... 230 4e-58
gi|17552674|ref|NP_498787.1| spectrin repeat and Calcium-binding... 230 4e-58
gi|477205|pir||A48403 alpha-actinin - Caenorhabditis elegans (fr... 229 6e-58
gi|17565036|ref|NP_506127.1| actinin (107.2 kD) (atn-1) [Caenorh... 229 6e-58
gi|17565034|ref|NP_506128.1| actinin (104.1 kD) (atn-1) [Caenorh... 229 6e-58
gi|28277312|gb|AAH46267.1| LOC398511 protein [Xenopus laevis] 229 1e-57
gi|11602888|gb|AAF93172.1| betaIV spectrin isoform sigma3 [Homo ... 229 1e-57
gi|6137376|pdb|1CUN|A Chain A, Crystal Structure Of Repeats 16 A... 221 3e-55
gi|25021548|ref|XP_110503.2| microtubule-actin crosslinking fact... 220 5e-55
gi|14285343|sp|Q9QXZ0|MACF_MOUSE Microtubule-actin crosslinking ... 216 5e-54
gi|30407952|gb|AAP30027.1| cardiomyocyte alpha-spectrin [Canis f... 213 7e-53
gi|555419|gb|AAA48566.1| alpha-actinin 213 7e-53
gi|2345081|gb|AAC02791.1| beta-spectrin [Homo sapiens] 212 1e-52
gi|23394914|gb|AAN31639.1| alpha-actinin [Biomphalaria glabrata] 209 6e-52
gi|91302|pir||A05283 spectrin alpha chain - mouse (fragment) >gn... 209 8e-52
gi|112957|sp|P05095|AACT_DICDI Alpha-actinin, non-muscular (F-ac... 208 1e-51
gi|42656943|ref|XP_293669.4| similar to actinin, alpha 4 [Homo s... 208 2e-51
gi|50747531|ref|XP_426369.1| PREDICTED: similar to unc93 homolog... 205 1e-50
gi|6273778|gb|AAF06360.1| trabeculin-alpha [Homo sapiens] 203 6e-50
gi|553648|gb|AAA60569.1| erythrocyte alpha-spectrin 202 8e-50
gi|14285345|sp|Q9UPN3|MACF_HUMAN Microtubule-actin crosslinking ... 200 5e-49
gi|5821434|dbj|BAA83821.1| actin binding protein ABP620 [Homo sa... 200 5e-49
gi|33188445|ref|NP_036222.3| microfilament and actin filament cr... 200 5e-49
gi|33188443|ref|NP_149033.2| microfilament and actin filament cr... 200 5e-49
gi|11137614|emb|CAC15920.1| dJ562N20.1.1 (trabeculin alpha (acti... 200 5e-49
gi|30316105|sp|Q96PK2|MAC4_HUMAN Microtubule-actin crosslinking ... 199 6e-49
gi|6690788|gb|AAF24343.1| Short stop/Kakapo long isoform [Drosop... 199 8e-49
gi|7511874|pir||T13734 groovin gene protein - fruit fly (Drosoph... 199 8e-49
gi|24653491|ref|NP_725337.1| CG18076-PE [Drosophila melanogaster... 197 2e-48
gi|24653495|ref|NP_725338.1| CG18076-PC [Drosophila melanogaster... 197 2e-48
gi|24653487|ref|NP_725335.1| CG18076-PG [Drosophila melanogaster... 197 2e-48
gi|24653497|ref|NP_725339.1| CG18076-PH [Drosophila melanogaster... 197 2e-48
gi|24653493|ref|NP_523733.2| CG18076-PA [Drosophila melanogaster... 197 2e-48
gi|24653489|ref|NP_725336.1| CG18076-PB [Drosophila melanogaster... 197 2e-48
gi|47208193|emb|CAF95915.1| unnamed protein product [Tetraodon n... 197 3e-48
gi|47206713|emb|CAF90950.1| unnamed protein product [Tetraodon n... 196 7e-48
gi|11602887|gb|AAF93171.1| betaIV spectrin isoform sigma2 [Homo ... 193 5e-47
gi|17426164|gb|AAL39000.1| macrophin 1 isoform 2 [Homo sapiens] 192 1e-46
gi|17426161|gb|AAL38997.1| macrophin 1 isoform 4 [Homo sapiens] 192 1e-46
gi|630573|pir||S44621 C50C3.2 protein - Caenorhabditis elegans 190 4e-46
gi|34328014|dbj|BAA32310.3| KIAA0465 protein [Homo sapiens] 185 1e-44
gi|47228910|emb|CAG09425.1| unnamed protein product [Tetraodon n... 185 1e-44
gi|31227672|ref|XP_317924.1| ENSANGP00000011363 [Anopheles gambi... 182 8e-44
gi|19882219|ref|NP_598594.1| dystonin isoform a; bullous pemphig... 180 4e-43
gi|19882221|ref|NP_604443.1| dystonin isoform b; bullous pemphig... 180 4e-43
gi|226515|prf||1516310A beta spectrin 180 5e-43
gi|48095516|ref|XP_392311.1| similar to Short stop/Kakapo long i... 178 2e-42
gi|4699902|gb|AAB29441.2| alpha-spectrin [Drosophila melanogaster] 177 3e-42
gi|14719556|pdb|1HCI|A Chain A, Crystal Structure Of The Rod Dom... 168 2e-39
gi|34304490|gb|AAQ63199.1| alpha-spectrin [Canis familiaris] 167 3e-39
gi|34577049|ref|NP_056363.2| bullous pemphigoid antigen 1 isofor... 163 7e-38
gi|34577047|ref|NP_899236.1| bullous pemphigoid antigen 1 isofor... 163 7e-38
gi|50744842|ref|XP_419901.1| PREDICTED: similar to Bullous pemph... 160 4e-37
gi|27923958|sp|O94833|BPEA_HUMAN Bullous pemphigoid antigen 1, i... 158 2e-36
gi|18157651|gb|AAL62061.1| bullous pemphigoid antigen 1 eA [Homo... 158 2e-36
gi|17865660|sp|O97592|DMD_CANFA Dystrophin >gnl|BL_ORD_ID|139613... 158 2e-36
gi|12834317|dbj|BAB22865.1| unnamed protein product [Mus musculus] 156 8e-36
gi|7512993|pir||T00079 hypothetical protein KIAA0465 - human (fr... 154 3e-35
gi|5032287|ref|NP_004000.1| dystrophin Dp427p1 isoform; dystroph... 154 4e-35
gi|5032285|ref|NP_003998.1| dystrophin Dp427l isoform; dystrophi... 154 4e-35
gi|5032281|ref|NP_000100.2| dystrophin Dp427c isoform; dystrophi... 154 4e-35
gi|5032283|ref|NP_003997.1| dystrophin Dp427m isoform; dystrophi... 154 4e-35
gi|34874618|ref|XP_237042.2| similar to bullous pemphigoid antig... 154 4e-35
gi|20521141|dbj|BAA34448.2| KIAA0728 protein [Homo sapiens] 153 5e-35
gi|34870961|ref|XP_342907.1| similar to macrophin 1 isoform 4 [R... 153 7e-35
gi|30846|emb|CAA32479.1| unnamed protein product [Homo sapiens] 152 9e-35
gi|87340|pir||A27605 dystrophin, muscle - human >gnl|BL_ORD_ID|8... 151 2e-34
gi|1314716|gb|AAA99797.1| alpha-spectrin 150 4e-34
gi|50742570|ref|XP_419679.1| PREDICTED: similar to Nesprin 1 (Nu... 150 6e-34
gi|11276931|pir||T42694 hypothetical protein DKFZp434J0328.1 - h... 149 1e-33
gi|118685|sp|P11532|DMD_HUMAN Dystrophin 149 1e-33
gi|26346759|dbj|BAC37028.1| unnamed protein product [Mus musculus] 147 4e-33
gi|45384284|ref|NP_990630.1| dystrophin [Gallus gallus] >gnl|BL_... 147 5e-33
gi|47155480|dbj|BAD18922.1| alpha 2 actinin [Equus caballus] 145 2e-32
gi|6681203|ref|NP_031894.1| dystrophin, muscular dystrophy; Duch... 141 2e-31
gi|39104621|dbj|BAC65573.2| mKIAA0465 protein [Mus musculus] 141 2e-31
gi|1169358|sp|P11531|DMD_MOUSE Dystrophin >gnl|BL_ORD_ID|327534 ... 141 3e-31
gi|32450315|gb|AAH53828.1| Unknown (protein for IMAGE:6873085) [... 138 2e-30
gi|24581873|ref|NP_524924.2| CG18251-PB [Drosophila melanogaster... 138 2e-30
gi|45552221|ref|NP_995633.1| CG18251-PC [Drosophila melanogaster... 138 2e-30
gi|871044|emb|CAA48702.1| alpha-actinin [Gallus gallus] 137 3e-30
gi|5032291|ref|NP_004003.1| dystrophin Dp260-2 isoform; dystroph... 137 5e-30
gi|5032289|ref|NP_004002.1| dystrophin Dp260-1 isoform; dystroph... 137 5e-30
gi|33300472|emb|CAD90188.2| Hypothetical protein ZK1151.1c [Caen... 136 9e-30
gi|7510926|pir||T26964 hypothetical protein ZK1151.2b - Caenorha... 136 9e-30
gi|27763989|emb|CAD44324.1| VAB-10B protein [Caenorhabditis eleg... 136 9e-30
gi|17511189|ref|NP_492995.1| VAB-10B protein family member, Vari... 136 9e-30
gi|7510925|pir||T26963 hypothetical protein ZK1151.2a - Caenorha... 136 9e-30
gi|17511187|ref|NP_492996.1| VAB-10B protein family member, Vari... 136 9e-30
gi|26342072|dbj|BAC34698.1| unnamed protein product [Mus musculus] 135 1e-29
gi|30315803|emb|CAD67584.1| putative dystrophin [Takifugu rubripes] 135 2e-29
gi|41281987|ref|NP_892006.1| nesprin 1 longest; synaptic nuclei ... 135 2e-29
gi|29839561|sp|Q8NF91|SNE1_HUMAN Nesprin 1 (Nuclear envelope spe... 135 2e-29
gi|48120804|ref|XP_393229.1| similar to CG18251-PB [Apis mellifera] 134 4e-29
gi|239922|gb|AAB20540.1| beta-spectrin subunit [mice, brain, Pep... 132 1e-28
gi|23097308|ref|NP_149062.1| nesprin 1 isoform longer; synaptic ... 132 1e-28
gi|48094523|ref|XP_392136.1| similar to CG18214-PA [Apis mellifera] 131 2e-28
gi|480073|pir||S36394 alpha-actinin 2, skeletal muscle splice fo... 131 3e-28
gi|50470589|emb|CAH04759.1| Hypothetical protein ZK1151.1g [Caen... 130 4e-28
gi|47213754|emb|CAF96419.1| unnamed protein product [Tetraodon n... 129 1e-27
gi|20521662|dbj|BAA34516.2| KIAA0796 protein [Homo sapiens] 128 2e-27
gi|19526753|ref|NP_056108.1| nesprin 1 isoform beta; synaptic nu... 127 4e-27
gi|28195689|gb|AAO27774.1| nesprin-1 beta 2 [Homo sapiens] 127 4e-27
gi|34849883|tpg|DAA01060.1| TPA: spectrin-like protein of the nu... 127 4e-27
gi|50759868|ref|XP_417820.1| PREDICTED: similar to Microtubule-a... 126 7e-27
gi|576411|pdb|2SPC|A Chain A, Spectrin (One Repeat Unit) >gnl|BL... 126 7e-27
gi|37360066|dbj|BAC98011.1| mKIAA0728 protein [Mus musculus] 125 1e-26
gi|47224004|emb|CAG12833.1| unnamed protein product [Tetraodon n... 125 2e-26
gi|47155482|dbj|BAD18923.1| alpha 3 actinin [Equus caballus] 124 3e-26
gi|6005938|ref|NP_009055.1| utrophin; dystrophin-related protein... 124 4e-26
gi|34870957|ref|XP_216526.2| similar to microtubule-actin crossl... 123 8e-26
gi|2345080|gb|AAC02790.1| beta-spectrin [Homo sapiens] 123 8e-26
gi|47550975|ref|NP_999661.1| dystrophin-like protein [Strongyloc... 123 8e-26
gi|50798042|ref|XP_428326.1| PREDICTED: similar to Spectrin beta... 120 4e-25
gi|2392151|pdb|1AJ3| Solution Structure Of The Spectrin Repeat,... 120 4e-25
gi|45439359|ref|NP_009049.2| triple functional domain (PTPRF int... 120 6e-25
gi|13430206|gb|AAK25769.1| non-erythrocyte beta-spectrin [Rattus... 120 6e-25
gi|27370625|gb|AAH35585.1| Similar to triple functional domain (... 120 6e-25
gi|5822388|pdb|1QUU|A Chain A, Crystal Structure Of Two Central ... 119 1e-24
gi|27801760|emb|CAD44516.1| VAB-10B protein [Caenorhabditis eleg... 118 2e-24
gi|21756268|dbj|BAC04848.1| unnamed protein product [Homo sapiens] 118 2e-24
gi|3522970|gb|AAC34245.1| Trio [Homo sapiens] 117 3e-24
gi|8928460|sp|O75962|TRIO_HUMAN Triple functional domain protein... 117 3e-24
gi|31202361|ref|XP_310129.1| ENSANGP00000019967 [Anopheles gambi... 117 5e-24
gi|47210347|emb|CAF90604.1| unnamed protein product [Tetraodon n... 117 5e-24
gi|16549862|dbj|BAB70870.1| unnamed protein product [Homo sapiens] 117 5e-24
gi|6708476|gb|AAF25952.1| Rho family guanine nucleotide exchange... 116 9e-24
gi|24654944|ref|NP_651960.2| CG18214-PA [Drosophila melanogaster... 116 9e-24
gi|47168509|pdb|1OWA|A Chain A, Solution Structural Studies On H... 116 9e-24
gi|19705491|ref|NP_599208.1| nesprin-1 [Rattus norvegicus] >gnl|... 115 1e-23
gi|34854901|ref|XP_226888.2| similar to Triple functional domain... 115 2e-23
gi|50807536|ref|XP_428917.1| PREDICTED: similar to betaIV-spectr... 115 2e-23
gi|10880799|gb|AAG24393.1| Syne-1B [Mus musculus] 114 3e-23
gi|8096219|dbj|BAA96093.1| Trio [Drosophila melanogaster] 114 3e-23
gi|482422|pir||A45929 spectrin beta chain - mouse (fragment) 113 6e-23
gi|224116|prf||1010302B spectrin beta fragment 112 1e-22
gi|554276|gb|AAA40126.1| beta-spectrin 112 2e-22
gi|47229500|emb|CAF99488.1| unnamed protein product [Tetraodon n... 111 2e-22
gi|6981696|ref|NP_037202.1| utrophin; utrophin (homologous to dy... 111 3e-22
gi|10799514|emb|CAC12899.1| dJ361I14.2 (novel protein (similar t... 111 3e-22
gi|50809216|ref|XP_429009.1| PREDICTED: similar to Spectrin beta... 110 4e-22
gi|443265|pdb|1SHG| Alpha Spectrin (Sh3 Domain) >gnl|BL_ORD_ID|... 110 5e-22
gi|32408715|ref|XP_324838.1| hypothetical protein [Neurospora cr... 109 9e-22
gi|338334|gb|AAA60572.1| erythrocyte beta-spectrin 109 9e-22
gi|2984657|gb|AAC07988.1| centrosomal Nek2-associated protein 1 ... 109 1e-21
gi|21735548|ref|NP_009117.2| centrosomal protein 2; centrosome a... 109 1e-21
gi|16974921|pdb|1HD3|A Chain A, A-Spectrin Sh3 Domain F52y Mutant 109 1e-21
gi|5107624|pdb|1PWT| Thermodynamic Analysis Of Alpha-Spectrin S... 108 2e-21
gi|14195007|sp|Q15149|PLE1_HUMAN Plectin 1 (PLTN) (PCN) (Hemides... 108 2e-21
gi|28373998|pdb|1NEG|A Chain A, Crystal Structure Analysis Of N-... 108 2e-21
gi|46575908|ref|NP_035812.2| utrophin; G-utrophin [Mus musculus]... 107 3e-21
gi|29497|emb|CAA42098.1| beta-spectrin [Homo sapiens] 107 6e-21
gi|2511779|gb|AAC79502.1| beta III spectrin [Homo sapiens] 107 6e-21
gi|7650388|gb|AAF66018.1| Kalirin-9a [Rattus norvegicus] 106 7e-21
gi|3024052|sp|P97924|HAPI_RAT Huntingtin-associated protein-inte... 106 7e-21
gi|14091744|ref|NP_114451.1| huntingtin-associated protein inter... 106 7e-21
gi|7514039|pir||T32732 PAM C-terminal interactor protein, clone ... 106 7e-21
gi|7767545|gb|AAF69144.1| Kalirin-7c isoform [Rattus norvegicus] 106 7e-21
gi|10120877|pdb|1QKW|A Chain A, Alpha-Spectrin Src Homology 3 Do... 106 7e-21
gi|46015861|pdb|1UUE|A Chain A, A-Spectrin Sh3 Domain (V44t, D48... 106 1e-20
gi|16975441|pdb|1E6H|A Chain A, A-Spectrin Sh3 Domain A11v, M25i... 105 1e-20
gi|12084430|pdb|1QKX|A Chain A, Alpha-Spectrin Src Homology 3 Do... 105 1e-20
gi|41322914|ref|NP_958785.1| plectin 1 isoform 10; hemidesmosoma... 105 2e-20
gi|41322908|ref|NP_958781.1| plectin 1 isoform 3; hemidesmosomal... 105 2e-20
gi|47607492|ref|NP_000436.2| plectin 1 isoform 1; hemidesmosomal... 105 2e-20
gi|41322912|ref|NP_958780.1| plectin 1 isoform 2; hemidesmosomal... 105 2e-20
gi|41322919|ref|NP_958784.1| plectin 1 isoform 8; hemidesmosomal... 105 2e-20
gi|41322923|ref|NP_958786.1| plectin 1 isoform 11; hemidesmosoma... 105 2e-20
gi|41322910|ref|NP_958783.1| plectin 1 isoform 7; hemidesmosomal... 105 2e-20
gi|41322916|ref|NP_958782.1| plectin 1 isoform 6; hemidesmosomal... 105 2e-20
gi|16975418|pdb|1E6G|A Chain A, A-Spectrin Sh3 Domain A11v, V23l... 104 3e-20
gi|31615297|pdb|1E7O|A Chain A, A-Spectrin Sh3 Domain A11v, V23l... 104 3e-20
gi|21465587|pdb|1H8K|A Chain A, A-Spectrin Sh3 Domain A11v, V23l... 103 5e-20
gi|4558122|pdb|1BK2| A-Spectrin Sh3 Domain D48g Mutant 103 6e-20
gi|182243|gb|AAA53103.1| erythrocyte alpha-spectrin 103 8e-20
gi|26336791|dbj|BAC32078.1| unnamed protein product [Mus musculus] 103 8e-20
gi|4504335|ref|NP_003938.1| huntingtin-associated protein intera... 102 1e-19
gi|7512342|pir||T08621 centrosome associated protein CEP250 - hu... 102 2e-19
gi|7511962|pir||T13030 microtubule binding protein D-CLIP-190 - ... 101 3e-19
gi|40849906|gb|AAR95665.1| plectin 11 [Rattus norvegicus] 101 3e-19
gi|40849900|gb|AAR95662.1| plectin 8 [Rattus norvegicus] 101 3e-19
gi|40849892|gb|AAR95658.1| plectin 4 [Rattus norvegicus] >gnl|BL... 101 3e-19
gi|40849886|gb|AAR95655.1| plectin 1 [Rattus norvegicus] 101 3e-19
gi|40849896|gb|AAR95660.1| plectin 6 [Rattus norvegicus] 101 3e-19
gi|40849888|gb|AAR95656.1| plectin 2 [Rattus norvegicus] 101 3e-19
gi|40849890|gb|AAR95657.1| plectin 3 [Rattus norvegicus] 101 3e-19
gi|40849898|gb|AAR95661.1| plectin 7 [Rattus norvegicus] 101 3e-19
gi|40849904|gb|AAR95664.1| plectin 10 [Rattus norvegicus] 101 3e-19
gi|3758911|emb|CAA09870.1| Kakapo [Drosophila melanogaster] 100 4e-19
gi|7489885|pir||T14867 interaptin - slime mold (Dictyostelium di... 100 4e-19
gi|7511951|pir||T13714 kakapo gene protein - fruit fly (Drosophi... 100 4e-19
gi|15238181|ref|NP_198994.1| COP1-interactive protein 1 / CIP1 [... 100 5e-19
gi|2345082|gb|AAC02792.1| beta-spectrin [Homo sapiens] 100 7e-19
gi|48111808|ref|XP_396309.1| similar to hypothetical protein [Ap... 100 7e-19
gi|47218355|emb|CAG04187.1| unnamed protein product [Tetraodon n... 100 9e-19
gi|34881930|ref|XP_347351.1| similar to dystrophin major muscle ... 99 2e-18
gi|34880638|ref|XP_229016.2| similar to dystrophin major muscle ... 99 2e-18
gi|13540714|ref|NP_071796.1| plectin [Rattus norvegicus] >gnl|BL... 99 2e-18
gi|24584806|ref|NP_609835.2| CG5020-PA [Drosophila melanogaster]... 98 3e-18
gi|45552035|ref|NP_788072.2| CG5020-PD [Drosophila melanogaster]... 98 3e-18
gi|28574245|ref|NP_724047.2| CG5020-PB [Drosophila melanogaster]... 98 3e-18
gi|24584810|ref|NP_724048.1| CG5020-PC [Drosophila melanogaster]... 98 3e-18
gi|17552086|ref|NP_499140.1| calcium-binding EF-hand containing ... 97 4e-18
gi|627059|pir||A45592 liver stage antigen LSA-1 - malaria parasi... 97 4e-18
gi|49068184|ref|XP_398381.1| hypothetical protein UM00766.1 [Ust... 97 6e-18
gi|4502443|ref|NP_001714.1| bullous pemphigoid antigen 1 isoform... 97 6e-18
gi|29561802|emb|CAD87820.1| SI:dZ230D15.1 (novel protein similar... 97 8e-18
gi|23508159|ref|NP_700829.1| liver stage antigen, putative [Plas... 97 8e-18
gi|47224100|emb|CAG12929.1| unnamed protein product [Tetraodon n... 96 1e-17
gi|32411607|ref|XP_326284.1| hypothetical protein [Neurospora cr... 96 1e-17
gi|7442004|pir||G02520 plectin - human >gnl|BL_ORD_ID|215627 gi|... 96 1e-17
gi|48425543|pdb|1S35|A Chain A, Crystal Structure Of Repeats 8 A... 96 2e-17
gi|2119533|pir||I52300 giantin - human >gnl|BL_ORD_ID|1705043 gi... 95 3e-17
gi|7494129|pir||T18296 myosin heavy chain - Entamoeba histolytic... 95 3e-17
gi|34880575|ref|XP_229019.2| similar to dystrophin major muscle ... 94 4e-17
gi|31227668|ref|XP_317923.1| ENSANGP00000011373 [Anopheles gambi... 94 4e-17
gi|31873814|emb|CAD97849.1| hypothetical protein [Homo sapiens] 94 6e-17
gi|4758454|ref|NP_004478.1| golgi autoantigen, golgin subfamily ... 93 8e-17
gi|46125813|ref|XP_387460.1| hypothetical protein FG07284.1 [Gib... 92 1e-16
gi|50286051|ref|XP_445454.1| unnamed protein product [Candida gl... 92 2e-16
gi|31216104|ref|XP_316167.1| ENSANGP00000020328 [Anopheles gambi... 92 2e-16
gi|50419075|ref|XP_458060.1| unnamed protein product [Debaryomyc... 91 3e-16
gi|38344252|emb|CAE04334.2| OSJNBa0008M17.5 [Oryza sativa (japon... 91 4e-16
gi|47202533|emb|CAF87908.1| unnamed protein product [Tetraodon n... 91 5e-16
gi|3986196|dbj|BAA34955.1| myosin heavy chain [Dugesia japonica] 90 9e-16
gi|27477057|ref|NP_598541.2| translocated promoter region protei... 89 1e-15
gi|50308363|ref|XP_454183.1| unnamed protein product [Kluyveromy... 89 2e-15
gi|1827866|pdb|1TUC| Alpha-Spectrin Src Homology 3 Domain, Circ... 89 2e-15
gi|50748027|ref|XP_421078.1| PREDICTED: similar to golgi-associa... 88 4e-15
gi|13549164|gb|AAK29675.1| alpha-spectrin [Gallus gallus] 87 5e-15
gi|50728478|ref|XP_416138.1| PREDICTED: similar to Early endosom... 86 1e-14
gi|28193204|emb|CAD62344.1| unnamed protein product [Homo sapiens] 86 1e-14
gi|50796692|ref|XP_428221.1| PREDICTED: similar to beta4-spectri... 86 1e-14
gi|127774|sp|P08799|MYS2_DICDI Myosin II heavy chain, non muscle... 86 1e-14
gi|49111879|ref|XP_411844.1| hypothetical protein AN7707.2 [Aspe... 86 2e-14
gi|15193244|gb|AAK91740.1| axoneme-associated protein GASP-180 [... 85 2e-14
gi|27529744|dbj|BAA74889.2| KIAA0866 protein [Homo sapiens] 85 2e-14
gi|5032313|ref|NP_004014.1| dystrophin Dp140bc isoform; dystroph... 85 2e-14
gi|109322|pir||A41604 myosin heavy chain, smooth muscle, long sp... 85 2e-14
gi|1346644|sp|P35748|MYHB_RABIT Myosin heavy chain, smooth muscl... 85 2e-14
gi|13124879|ref|NP_002465.1| smooth muscle myosin heavy chain 11... 85 2e-14
gi|5032307|ref|NP_004011.1| dystrophin Dp140c isoform; dystrophi... 85 2e-14
gi|5032311|ref|NP_004013.1| dystrophin Dp140ab isoform; dystroph... 85 2e-14
gi|5032309|ref|NP_004012.1| dystrophin Dp140b isoform; dystrophi... 85 2e-14
gi|7416982|gb|AAF62394.1| myosin heavy chain cardiac muscle spec... 85 2e-14
gi|2104553|gb|AAC31665.1| Myosin heavy chain (MHY11) (5'partial)... 85 2e-14
gi|13124875|ref|NP_074035.1| smooth muscle myosin heavy chain 11... 85 2e-14
gi|5032293|ref|NP_004004.1| dystrophin Dp140 isoform; dystrophin... 85 2e-14
gi|50734763|ref|XP_419004.1| PREDICTED: similar to triple functi... 85 2e-14
gi|1408194|gb|AAB03661.1| myosin heavy chain [Placopecten magell... 85 3e-14
gi|17227154|gb|AAL38031.1| myocyte inner nuclear membrane protei... 85 3e-14
gi|11276951|pir||A59287 myosin heavy chain - fluke (Schistosoma ... 84 4e-14
gi|497653|gb|AAC46490.1| myosin heavy chain >gnl|BL_ORD_ID|76853... 84 5e-14
gi|7416979|gb|AAF62391.1| myosin heavy chain striated muscle spe... 84 5e-14
gi|7416983|gb|AAF62395.1| myosin heavy chain cardiac muscle spec... 84 5e-14
gi|7416980|gb|AAF62392.1| myosin heavy chain catch (smooth) musc... 84 5e-14
gi|1408192|gb|AAB03660.1| myosin heavy chain [Placopecten magell... 84 5e-14
gi|127773|sp|P24733|MYS_AEQIR Myosin heavy chain, striated muscl... 84 5e-14
gi|236789|gb|AAB19995.1| myosin heavy chain=rod region [Aequipec... 84 5e-14
gi|48143056|ref|XP_397404.1| similar to dystrophin-like protein ... 84 7e-14
gi|10863905|ref|NP_004230.1| thyroid hormone receptor interactor... 84 7e-14
gi|50744838|ref|XP_419899.1| PREDICTED: similar to bullous pemph... 83 9e-14
gi|5817598|gb|AAD52842.1| myosin heavy chain [Pecten maximus] 83 1e-13
gi|20070691|gb|AAH26142.1| Myh11 protein [Mus musculus] 83 1e-13
gi|127743|sp|P02566|MYSB_CAEEL Myosin heavy chain B (MHC B) >gnl... 82 1e-13
gi|38110842|gb|EAA56504.1| hypothetical protein MG06475.4 [Magna... 82 1e-13
gi|1304604|gb|AAB01089.1| alpha-actinin 82 1e-13
gi|17509401|ref|NP_493596.1| UNCoordinated locomotion UNC-54, en... 82 1e-13
gi|3986194|dbj|BAA34954.1| myosin heavy chain [Dugesia japonica] 82 2e-13
gi|1827865|pdb|1TUD| Alpha-Spectrin Src Homology 3 Domain, Circ... 82 2e-13
gi|32441707|emb|CAD67583.1| putative utrophin [Takifugu rubripes] 82 2e-13
gi|2253417|gb|AAD09135.1| Trip230 [Homo sapiens] 82 3e-13
gi|47224613|emb|CAG03597.1| unnamed protein product [Tetraodon n... 82 3e-13
gi|18652658|gb|AAD28718.2| myosin heavy chain A [Schmidtea medit... 81 3e-13
gi|20891813|ref|XP_147228.1| myosin heavy chain 11, smooth muscl... 81 4e-13
gi|50510675|dbj|BAD32323.1| mKIAA0866 protein [Mus musculus] 81 4e-13
gi|21754039|dbj|BAC04449.1| unnamed protein product [Homo sapiens] 81 4e-13
gi|4502781|ref|NP_001804.1| centromere protein E; Centromere aut... 81 4e-13
gi|49523259|gb|AAH75407.1| Unknown (protein for MGC:89159) [Xeno... 80 6e-13
gi|44890896|dbj|BAD12120.1| SPTAN1 [Sus scrofa] 80 1e-12
gi|47219799|emb|CAG03426.1| unnamed protein product [Tetraodon n... 80 1e-12
gi|13431707|sp|Q28641|MYH4_RABIT Myosin heavy chain, skeletal mu... 80 1e-12
gi|29351639|gb|AAH49289.1| SYNE1 protein [Xenopus laevis] 79 1e-12
gi|20357504|ref|NP_065121.2| bullous pemphigoid antigen 1 isofor... 79 1e-12
gi|41350836|gb|AAH65536.1| DST protein [Homo sapiens] 79 1e-12
gi|39588011|emb|CAE57242.1| Hypothetical protein CBG00120 [Caeno... 79 2e-12
gi|1777305|dbj|BAA19070.1| myosin heavy chain [Theragra chalcogr... 79 2e-12
gi|382658|prf||1819485A CENP-E protein 79 2e-12
gi|3041707|sp|P13535|MYH8_HUMAN Myosin heavy chain, skeletal mus... 79 2e-12
gi|2119300|pir||I38055 myosin heavy chain, perinatal skeletal mu... 79 2e-12
gi|4505301|ref|NP_002463.1| myosin, heavy polypeptide 8, skeleta... 79 2e-12
gi|50740550|ref|XP_419492.1| PREDICTED: similar to Spectrin beta... 79 2e-12
gi|30315935|sp|Q8WXK8|BPEB_HUMAN Bullous pemphigoid antigen 1, i... 79 2e-12
gi|2345079|gb|AAC02789.1| beta-spectrin [Homo sapiens] 78 3e-12
gi|27803037|emb|CAD60740.1| unnamed protein product [Podospora a... 78 3e-12
gi|28972888|dbj|BAC65860.1| mKIAA3005 protein [Mus musculus] 78 4e-12
gi|20302065|ref|NP_620240.1| golgi-associated protein GCP360 [Ra... 78 4e-12
gi|33598964|ref|NP_780469.1| myosin heavy chain 10, non-muscle; ... 78 4e-12
gi|20521726|dbj|BAA76855.2| KIAA1011 protein [Homo sapiens] 78 4e-12
gi|47208995|emb|CAF91401.1| unnamed protein product [Tetraodon n... 77 5e-12
gi|32407187|ref|XP_324183.1| hypothetical protein [Neurospora cr... 77 5e-12
gi|33624848|ref|NP_055995.3| synaptic nuclei expressed gene 2 is... 77 5e-12
gi|24417711|gb|AAN60443.1| nesprin-2 [Homo sapiens] 77 5e-12
gi|4417214|dbj|BAA36971.1| smooth muscle myosin heavy chain [Hom... 77 5e-12
gi|17861384|gb|AAL33802.1| nesprin-2 gamma [Homo sapiens] 77 5e-12
gi|47216758|emb|CAG03762.1| unnamed protein product [Tetraodon n... 77 5e-12
gi|47208842|emb|CAF94383.1| unnamed protein product [Tetraodon n... 77 5e-12
gi|17016967|gb|AAL33548.1| NUANCE [Homo sapiens] 77 5e-12
gi|29839588|sp|Q8WXH0|SNE2_HUMAN Nesprin 2 (Nuclear envelope spe... 77 5e-12
gi|11276954|pir||A59234 slow myosin heavy chain 3 - quail >gnl|B... 77 5e-12
gi|33624879|ref|NP_878918.1| synaptic nuclei expressed gene 2 is... 77 5e-12
>gi|17569483|ref|NP_508537.1| spectrin (spc-1) [Caenorhabditis
elegans]
gi|7441356|pir||T16613 hypothetical protein K10B3.10 - Caenorhabditis
elegans
gi|1206048|gb|AAB53876.1| Spectrin protein 1 [Caenorhabditis elegans]
Length = 2427
Score = 4681 bits (12142), Expect = 0.0
Identities = 2370/2427 (97%), Positives = 2370/2427 (97%)
Frame = -1
Query: 7284 MADSNDTHAXXXXXXXXXXPQEIRILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEA 7105
MADSNDTHA PQEIRILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEA
Sbjct: 1 MADSNDTHAPPEPVLEVPPPQEIRILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEA 60
Query: 7104 RQFQYFKRDADELNVWILEKLQTAQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLD 6925
RQFQYFKRDADELNVWILEKLQTAQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLD
Sbjct: 61 RQFQYFKRDADELNVWILEKLQTAQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLD 120
Query: 6924 KTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILY 6745
KTGNAMIQHNHFASEHIKKRLEELHALW KGIKLQQALKLLHFIRQCDEILY
Sbjct: 121 KTGNAMIQHNHFASEHIKKRLEELHALWDKLFFKLKDKGIKLQQALKLLHFIRQCDEILY 180
Query: 6744 WIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEH 6565
WIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEH
Sbjct: 181 WIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEH 240
Query: 6564 DQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDY 6385
DQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDY
Sbjct: 241 DQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDY 300
Query: 6384 GRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAW 6205
GRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAW
Sbjct: 301 GRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAW 360
Query: 6204 NALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESH 6025
NALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESH
Sbjct: 361 NALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESH 420
Query: 6024 QEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILY 5845
QEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILY
Sbjct: 421 QEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILY 480
Query: 5844 EQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKI 5665
EQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKI
Sbjct: 481 EQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKI 540
Query: 5664 NALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCD 5485
NALDEFATKLIQGQHYAADDVAE RGNALKESYKRQTFDRDCD
Sbjct: 541 NALDEFATKLIQGQHYAADDVAERRQALLDRRRRLLDRARQRGNALKESYKRQTFDRDCD 600
Query: 5484 EMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGH 5305
EMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGH
Sbjct: 601 EMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGH 660
Query: 5304 FAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVAS 5125
FAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVAS
Sbjct: 661 FAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVAS 720
Query: 5124 EDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQ 4945
EDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQ
Sbjct: 721 EDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQ 780
Query: 4944 QRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLI 4765
QRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLI
Sbjct: 781 QRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLI 840
Query: 4764 KKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRR 4585
KKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRR
Sbjct: 841 KKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRR 900
Query: 4584 TDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFK 4405
TDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFK
Sbjct: 901 TDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFK 960
Query: 4404 GTIEDLRKQASQCKYQEQPMGQLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDW 4225
GTIEDLRKQASQCKYQEQPMGQLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDW
Sbjct: 961 GTIEDLRKQASQCKYQEQPMGQLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDW 1020
Query: 4224 WKVEVNDRQGFVPAAYVKRIEPGTAQQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRK 4045
WKVEVNDRQGFVPAAYVKRIEPGTAQQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRK
Sbjct: 1021 WKVEVNDRQGFVPAAYVKRIEPGTAQQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRK 1080
Query: 4044 LEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVR 3865
LEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVR
Sbjct: 1081 LEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVR 1140
Query: 3864 LQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRD 3685
LQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRAL QLGSAHEVQRFHRD
Sbjct: 1141 LQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALEEQTEQREQQLGSAHEVQRFHRD 1200
Query: 3684 VDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQ 3505
VDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQ
Sbjct: 1201 VDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQ 1260
Query: 3504 SHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQL 3325
SHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQL
Sbjct: 1261 SHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQL 1320
Query: 3324 VSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQ 3145
VSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQ
Sbjct: 1321 VSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQ 1380
Query: 3144 GVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGDNVESL 2965
GVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGDNVESL
Sbjct: 1381 GVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGDNVESL 1440
Query: 2964 IKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQK 2785
IKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQK
Sbjct: 1441 IKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQK 1500
Query: 2784 RFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHANS 2605
RFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHANS
Sbjct: 1501 RFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHANS 1560
Query: 2604 DRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSF 2425
DRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSF
Sbjct: 1561 DRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSF 1620
Query: 2424 MAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADS 2245
MAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADS
Sbjct: 1621 MAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADS 1680
Query: 2244 LLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEK 2065
LLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEK
Sbjct: 1681 LLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEK 1740
Query: 2064 KLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQ 1885
KLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQ
Sbjct: 1741 KLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQ 1800
Query: 1884 IKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGE 1705
IKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGE
Sbjct: 1801 IKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGE 1860
Query: 1704 NMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIE 1525
NMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIE
Sbjct: 1861 NMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIE 1920
Query: 1524 IESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEA 1345
IESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEA
Sbjct: 1921 IESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEA 1980
Query: 1344 FDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXX 1165
FDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARR
Sbjct: 1981 FDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRQKLL 2040
Query: 1164 XXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSL 985
QIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSL
Sbjct: 2041 KMQQQFKQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSL 2100
Query: 984 SSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQ 805
SSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQ
Sbjct: 2101 SSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQ 2160
Query: 804 EENDKLRREFAKLANAFHAWLTNTRQEMMEAGGTLEEQLDAVERKAKEIKANKGQLRQIE 625
EENDKLRREFAKLANAFHAWLTNTRQEMMEAGGTLEEQLDAVERKAKEIKANKGQLRQIE
Sbjct: 2161 EENDKLRREFAKLANAFHAWLTNTRQEMMEAGGTLEEQLDAVERKAKEIKANKGQLRQIE 2220
Query: 624 EKGAMLERNLILDNRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALR 445
EKGAMLERNLILDNRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALR
Sbjct: 2221 EKGAMLERNLILDNRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALR 2280
Query: 444 EFSMMFKHFDKEKTGRLDHQQFKSCLRALGYDLPMVDEGQPEPEFQRILDIVDPNRDGYV 265
EFSMMFKHFDKEKTGRLDHQQFKSCLRALGYDLPMVDEGQPEPEFQRILDIVDPNRDGYV
Sbjct: 2281 EFSMMFKHFDKEKTGRLDHQQFKSCLRALGYDLPMVDEGQPEPEFQRILDIVDPNRDGYV 2340
Query: 264 TLQEYMAFMISKETENIQSSEEIEMAFRALSKEFRPYVTAEELYANLTPEQAEFCIRRMK 85
TLQEYMAFMISKETENIQSSEEIEMAFRALSKEFRPYVTAEELYANLTPEQAEFCIRRMK
Sbjct: 2341 TLQEYMAFMISKETENIQSSEEIEMAFRALSKEFRPYVTAEELYANLTPEQAEFCIRRMK 2400
Query: 84 PYMDAISGRSIQGGLDYEQFVHALFQS 4
PYMDAISGRSIQGGLDYEQFVHALFQS
Sbjct: 2401 PYMDAISGRSIQGGLDYEQFVHALFQS 2427
>gi|39597692|emb|CAE68383.1| Hypothetical protein CBG14139
[Caenorhabditis briggsae]
Length = 2427
Score = 4576 bits (11869), Expect = 0.0
Identities = 2312/2427 (95%), Positives = 2340/2427 (96%)
Frame = -1
Query: 7284 MADSNDTHAXXXXXXXXXXPQEIRILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEA 7105
MADSNDTHA PQEIRILETADDI QRRQEVLGHYS+FKDHSQTKRDRLEEA
Sbjct: 1 MADSNDTHAPPEPVLEVPPPQEIRILETADDIQQRRQEVLGHYSLFKDHSQTKRDRLEEA 60
Query: 7104 RQFQYFKRDADELNVWILEKLQTAQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLD 6925
RQFQYFKRDADELNVWILEKLQTAQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLD
Sbjct: 61 RQFQYFKRDADELNVWILEKLQTAQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLD 120
Query: 6924 KTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILY 6745
KTGNAMIQHNHFAS+HIK+RLEELHALW KGIKLQQALKLLHFIRQCDE+LY
Sbjct: 121 KTGNAMIQHNHFASDHIKRRLEELHALWDKLFFKLKDKGIKLQQALKLLHFIRQCDEVLY 180
Query: 6744 WIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEH 6565
WIREKETYVTAEDMGMDLEHVEILQRKFDDFLKEL NHQYRINEIN AADKLVEEGHSEH
Sbjct: 181 WIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELNNHQYRINEINGAADKLVEEGHSEH 240
Query: 6564 DQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDY 6385
DQIYKKRDDVNDAWHRLNTLA TRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDY
Sbjct: 241 DQIYKKRDDVNDAWHRLNTLAVTRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDY 300
Query: 6384 GRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAW 6205
GRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEA KLAETHPDR EAIHQKND T++AW
Sbjct: 301 GRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAVKLAETHPDRGEAIHQKNDSTRSAW 360
Query: 6204 NALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESH 6025
NALK KAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESH
Sbjct: 361 NALKNKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESH 420
Query: 6024 QEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILY 5845
QEHKGEIDARADSFNQTA+AGQKLVEMGIPESPEV+EKLEKL+ EKSSLLGLWEERRILY
Sbjct: 421 QEHKGEIDARADSFNQTAAAGQKLVEMGIPESPEVREKLEKLEAEKSSLLGLWEERRILY 480
Query: 5844 EQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKI 5665
EQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKI
Sbjct: 481 EQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKI 540
Query: 5664 NALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCD 5485
NALDEFATKLIQGQHYAADDVA+ RGNALKESYKRQTFDRDCD
Sbjct: 541 NALDEFATKLIQGQHYAADDVAKRRQALLDRRRRLLDRARQRGNALKESYKRQTFDRDCD 600
Query: 5484 EMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGH 5305
EMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQEL+ANENRLDDIRSTGEQII+SGH
Sbjct: 601 EMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQELRANENRLDDIRSTGEQIIESGH 660
Query: 5304 FAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVAS 5125
FAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVE WLSELEGQVAS
Sbjct: 661 FAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVELWLSELEGQVAS 720
Query: 5124 EDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQ 4945
EDYGKDLVSVQNLQKKIGL+ESDFNAHNDRVDGI+ LAQQF +EEHFNAPVI+RKQE LQ
Sbjct: 721 EDYGKDLVSVQNLQKKIGLLESDFNAHNDRVDGIRNLAQQFHQEEHFNAPVIIRKQEALQ 780
Query: 4944 QRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLI 4765
QRYNALRDPLEKRKRKLGES QGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLI
Sbjct: 781 QRYNALRDPLEKRKRKLGESLQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLI 840
Query: 4764 KKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRR 4585
KKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRR
Sbjct: 841 KKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRR 900
Query: 4584 TDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFK 4405
+LDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFK
Sbjct: 901 GELDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFK 960
Query: 4404 GTIEDLRKQASQCKYQEQPMGQLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDW 4225
GTIEDLRKQASQCKYQEQPMGQLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASN+DW
Sbjct: 961 GTIEDLRKQASQCKYQEQPMGQLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNKDW 1020
Query: 4224 WKVEVNDRQGFVPAAYVKRIEPGTAQQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRK 4045
WKVEVNDRQGFVPAAYVKRIEPGTAQQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRK
Sbjct: 1021 WKVEVNDRQGFVPAAYVKRIEPGTAQQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRK 1080
Query: 4044 LEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVR 3865
LEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVR
Sbjct: 1081 LEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVR 1140
Query: 3864 LQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRD 3685
LQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRAL QLGSAHEVQRFHRD
Sbjct: 1141 LQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALEEQTEQREQQLGSAHEVQRFHRD 1200
Query: 3684 VDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQ 3505
VDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQ
Sbjct: 1201 VDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQ 1260
Query: 3504 SHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQL 3325
SHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQL
Sbjct: 1261 SHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQL 1320
Query: 3324 VSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQ 3145
VSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQ
Sbjct: 1321 VSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQ 1380
Query: 3144 GVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGDNVESL 2965
GVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGDNVESL
Sbjct: 1381 GVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGDNVESL 1440
Query: 2964 IKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQK 2785
IKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQK
Sbjct: 1441 IKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQK 1500
Query: 2784 RFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHANS 2605
R KLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHANS
Sbjct: 1501 RSKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHANS 1560
Query: 2604 DRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSF 2425
DRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSF
Sbjct: 1561 DRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSF 1620
Query: 2424 MAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADS 2245
MAAVKDLEFWLGEVEILLQS DYGKDLASVENLLKKHSLLEADI AHQDRVGEMNEQADS
Sbjct: 1621 MAAVKDLEFWLGEVEILLQSADYGKDLASVENLLKKHSLLEADITAHQDRVGEMNEQADS 1680
Query: 2244 LLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEK 2065
LLENDQFQGQQIAERRKLIADRYDGVKKMA DRRDKLSKALNVHQFFRDIDDEESWIKEK
Sbjct: 1681 LLENDQFQGQQIAERRKLIADRYDGVKKMAADRRDKLSKALNVHQFFRDIDDEESWIKEK 1740
Query: 2064 KLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQ 1885
KLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQ
Sbjct: 1741 KLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQ 1800
Query: 1884 IKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGE 1705
IKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFG+
Sbjct: 1801 IKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGD 1860
Query: 1704 NMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIE 1525
NMAGVQGLLKKHDTFQVDLELHKQRVADLI KGD LI NGNHHAPHI+QRCDQLRARL+E
Sbjct: 1861 NMAGVQGLLKKHDTFQVDLELHKQRVADLIGKGDDLIQNGNHHAPHIRQRCDQLRARLVE 1920
Query: 1524 IESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEA 1345
IESMAE RLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEA
Sbjct: 1921 IESMAEKRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEA 1980
Query: 1344 FDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXX 1165
FDAGLNAFEHEGIQRITELKDQLV S HQQSPAIEKRHTNVIQRWQNLL+HSEARR
Sbjct: 1981 FDAGLNAFEHEGIQRITELKDQLVHSSHQQSPAIEKRHTNVIQRWQNLLSHSEARRQKLL 2040
Query: 1164 XXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSL 985
QIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAH EFQRSL
Sbjct: 2041 KMQQQFKQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHAEFQRSL 2100
Query: 984 SSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQ 805
SSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELA+EHQRQ
Sbjct: 2101 SSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAKEHQRQ 2160
Query: 804 EENDKLRREFAKLANAFHAWLTNTRQEMMEAGGTLEEQLDAVERKAKEIKANKGQLRQIE 625
EENDKLRREFAKLANAFH WLTNTRQEMMEAGGTLEEQLDAVE+KAKEIKANK QLRQIE
Sbjct: 2161 EENDKLRREFAKLANAFHTWLTNTRQEMMEAGGTLEEQLDAVEKKAKEIKANKVQLRQIE 2220
Query: 624 EKGAMLERNLILDNRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALR 445
+KGAMLERNLILDNRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGV+EEALR
Sbjct: 2221 DKGAMLERNLILDNRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVTEEALR 2280
Query: 444 EFSMMFKHFDKEKTGRLDHQQFKSCLRALGYDLPMVDEGQPEPEFQRILDIVDPNRDGYV 265
EFSMMFKHFDKEKTGRLDHQQFKSCLRALGYDLPMVDEGQPEPEFQRILDIVDPNRDGYV
Sbjct: 2281 EFSMMFKHFDKEKTGRLDHQQFKSCLRALGYDLPMVDEGQPEPEFQRILDIVDPNRDGYV 2340
Query: 264 TLQEYMAFMISKETENIQSSEEIEMAFRALSKEFRPYVTAEELYANLTPEQAEFCIRRMK 85
TLQEYMAFMISKETENIQSSEEIEMAFRALSKEFRPYVTAEELYANLTPEQAEFCI+RMK
Sbjct: 2341 TLQEYMAFMISKETENIQSSEEIEMAFRALSKEFRPYVTAEELYANLTPEQAEFCIKRMK 2400
Query: 84 PYMDAISGRSIQGGLDYEQFVHALFQS 4
PY D ISGR+IQGGLDYEQFVHALFQS
Sbjct: 2401 PYTDTISGRAIQGGLDYEQFVHALFQS 2427
>gi|31218879|ref|XP_316724.1| ENSANGP00000002653 [Anopheles gambiae]
gi|21299655|gb|EAA11800.1| ENSANGP00000002653 [Anopheles gambiae str.
PEST]
Length = 2417
Score = 3031 bits (7858), Expect = 0.0
Identities = 1499/2414 (62%), Positives = 1873/2414 (77%), Gaps = 7/2414 (0%)
Frame = -1
Query: 7224 QEIRILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEK 7045
+E+RILE+A+DI +RR +VL YS FK ++ KR++LE++R+FQYFKRD+DEL WI EK
Sbjct: 7 KEVRILESAEDIQERRDQVLNRYSEFKLETRQKREKLEDSRRFQYFKRDSDELESWINEK 66
Query: 7044 LQTAQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKR 6865
LQ A EE++RDP+NLQAKIQKH+AFEAEV AH+ I LD TG MI HFASE I++R
Sbjct: 67 LQAASEESYRDPTNLQAKIQKHQAFEAEVSAHSNAIVVLDNTGQEMINQGHFASETIQRR 126
Query: 6864 LEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEH 6685
LEEL LW KG+KLQQAL L+ F+R C+E+++WI++KE +VTA++ G DLEH
Sbjct: 127 LEELQRLWELLLSRLAEKGMKLQQALVLVQFLRHCEEVMFWIKDKEAFVTADEFGQDLEH 186
Query: 6684 VEILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTL 6505
VE+LQRKFD+F K++ + +YR+ E+N+ ADKL+ GH E + I +K++++N+AW RL L
Sbjct: 187 VEVLQRKFDEFQKDMASQEYRVTEVNELADKLLFGGHPERETITRKKEELNEAWQRLKQL 246
Query: 6504 AATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERD 6325
A R+E LFGAH++QRFNRDADET+AWI EKD+ LSSDDYGRDL +VQALQRKHEG ERD
Sbjct: 247 AILRQEKLFGAHEIQRFNRDADETVAWIAEKDVVLSSDDYGRDLASVQALQRKHEGVERD 306
Query: 6324 LAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQL 6145
LAALE K+ L EA +L H D +E I +K + A W +L KA+ RK L+ S+ L
Sbjct: 307 LAALEDKVAALGTEAGRLCSIHADHSEQIREKQAEIAAYWQSLTAKAKERKQKLDESYFL 366
Query: 6144 HRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASA 5965
HRFLAD+RDL+SWI MKA+I ADELAKDVAGAEALLE HQEHKGEIDAR DSF T A
Sbjct: 367 HRFLADFRDLVSWINGMKAIISADELAKDVAGAEALLERHQEHKGEIDARVDSFKLTTEA 426
Query: 5964 GQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWM 5785
G++L+E + EVQEKL L+++KSSLL LWE+RRILYEQCMDLQLFYRDTEQA+TWM
Sbjct: 427 GRQLLEREHYAAAEVQEKLAALENDKSSLLVLWEDRRILYEQCMDLQLFYRDTEQADTWM 486
Query: 5784 NKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADD 5605
KQEAFLAN DLGDSLDSVE LIKKHEDFEKSLAAQEEKI ALD FATKLI GQHYAADD
Sbjct: 487 AKQEAFLANEDLGDSLDSVEALIKKHEDFEKSLAAQEEKIKALDVFATKLIDGQHYAADD 546
Query: 5604 VAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLD 5425
VA+ R L++S Q F+RDCDE WI+EKL A DDSYLD
Sbjct: 547 VAQRRAMLLARRSALQEKSSVRQKLLEDSNALQQFERDCDETKGWISEKLKFATDDSYLD 606
Query: 5424 PTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNEL 5245
PTN+ GK+QKH NFE EL AN++R++DI +TG+++ H+AAD + R++++ LW L
Sbjct: 607 PTNLNGKVQKHTNFEHELTANKSRIEDITATGQELATKEHYAADKVNARMQEIVTLWESL 666
Query: 5244 VDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLI 5065
V A++KKG KL+EA +QQFNR +ED+E WLSE+EGQ+ SEDYGKDL SVQNLQKK L+
Sbjct: 667 VRASDKKGCKLQEASQQQQFNRTVEDIELWLSEVEGQLLSEDYGKDLTSVQNLQKKQALL 726
Query: 5064 ESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGES 4885
E+D AH DR++GIK A +F E HF+A I K+ L +RY AL +P+ RK++L +S
Sbjct: 727 EADVMAHQDRIEGIKVAANKFVESGHFDADNIRAKEAALSKRYAALAEPMSIRKQRLLDS 786
Query: 4884 HQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESV 4705
Q QLFRD+EDE AWIREKE VA STNRGRDLIGVQNLIKK QA++AEI NH+S+ V
Sbjct: 787 LQVQQLFRDLEDEAAWIREKEPVAASTNRGRDLIGVQNLIKKHQAVLAEINNHESRCAGV 846
Query: 4704 SSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEAD 4525
S M+ + + EI+ +L L+D W LK K+ +R+ DL+DSLQAHQY +DANEA+
Sbjct: 847 ISNGEQMLNEQPTASEEIKLRLDALKDQWNSLKEKSNQRKQDLEDSLQAHQYFADANEAE 906
Query: 4524 AWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQPM 4345
+WM EKEPIV + DYGKDEDS+EALLKKH AL+SDLEAF TI+ L++QA C+ QE P+
Sbjct: 907 SWMREKEPIVSNQDYGKDEDSSEALLKKHEALVSDLEAFGNTIQALQEQAKNCRQQETPV 966
Query: 4344 GQL-GRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKR 4168
+ G++CV+ALYDY EKSPREVSMKK DVLTLLN++N+DWWKVEVNDRQGFVPAAY+K+
Sbjct: 967 VDITGKECVMALYDYTEKSPREVSMKKNDVLTLLNSNNKDWWKVEVNDRQGFVPAAYIKK 1026
Query: 4167 IEPG-TAQQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLA 3991
I+PG +A Q +SI +Q++I +Y L+ L R+ KL E K Y L+REA DLA
Sbjct: 1027 IDPGLSASQQNLIDGHSIAKRQTQINSQYDNLLALARERQNKLNETVKAYVLVREAADLA 1086
Query: 3990 EWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTE 3811
WIK +E+ A +++G DLE+VEVLQKKFDDF DLKANEVRL ++N+IA LTS+GQTE
Sbjct: 1087 AWIKDKESHAQIKDVGEDLEEVEVLQKKFDDFNDDLKANEVRLAKLNEIAIQLTSLGQTE 1146
Query: 3810 TAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSE 3631
A++I+ QI+ LN W L QLGSAHEVQRFHRDVDET+DWI EK++AL+++
Sbjct: 1147 AALKIKTQIQTLNEEWATLQTITQERASQLGSAHEVQRFHRDVDETKDWIAEKENALNND 1206
Query: 3630 DFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNE 3451
+ G+DLR VQ LQRKHEG+ERDLAAL DKI+ LDE ANRL QSHP+ AEQ Y Q+E+NE
Sbjct: 1207 ELGKDLRGVQTLQRKHEGLERDLAALQDKIRQLDETANRLMQSHPDTAEQTYAKQKEINE 1266
Query: 3450 QWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLE 3271
+W ++ +KA RKEKLLDSYD QRFLSDYRDL WI+SM LV+S+ELANDVTGAEAL+E
Sbjct: 1267 EWQQVVTKAQQRKEKLLDSYDLQRFLSDYRDLSAWISSMMGLVTSEELANDVTGAEALIE 1326
Query: 3270 RHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRN 3091
RHQE+RTE+D+RA TF AF+QFGN+LL ++HYAA +I+ +++ +N+AR+ LE AW ARR
Sbjct: 1327 RHQEHRTEVDARAGTFSAFEQFGNELLQANHYAAPEIQEKIENLNKAREELERAWTARRL 1386
Query: 3090 ILDQCLELQLFYRDCEQADTWMSAREAFLAQE--DPSGDNVESLIKKHEDFDKAINTQEE 2917
LDQ L+LQL+ RDCEQA+ WMSAREAFL E D GDNVE+LIKKHEDFDKAIN EE
Sbjct: 1387 QLDQNLDLQLYLRDCEQAENWMSAREAFLNAEEVDSKGDNVEALIKKHEDFDKAINGHEE 1446
Query: 2916 KIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRD 2737
KI L++ A+ LI HY + KR ++LDRW LKE LI+KR +LG+ QTLQQFSRD
Sbjct: 1447 KIGALQVLADQLIAQEHYAGRLIDAKRQEVLDRWRHLKEDLIEKRSRLGDEQTLQQFSRD 1506
Query: 2736 ADEIENWMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIEN 2557
ADEIENW+ EK Q+A EE+Y+DP NIQ KHQK QAFEAEL AN+DRI++++ G+NLI+
Sbjct: 1507 ADEIENWIAEKLQLATEESYKDPANIQSKHQKHQAFEAELAANADRISSVLAMGSNLIDR 1566
Query: 2556 AKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEI 2377
+C G E AV RL + DQW+ L + TTEKS +LKEANKQ++++AAVKDL+FWLGEVE
Sbjct: 1567 NQCSGSEEAVQKRLTQIADQWEYLTQKTTEKSLKLKEANKQRTYIAAVKDLDFWLGEVES 1626
Query: 2376 LLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERR 2197
LL SED GKDLASV+NL+KKH L+EADI AH+DR+ +MN QADSL+E+ QF I E+R
Sbjct: 1627 LLTSEDAGKDLASVQNLMKKHQLVEADIHAHEDRIKDMNSQADSLVESGQFDSAGIQEKR 1686
Query: 2196 KLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGV 2017
+ I +RY+ ++ +A R+ +L++A +HQFFRDI DEESWIKEKKLLV SDDYGRDL GV
Sbjct: 1687 QSINERYERIRNLAAHRQARLNEANTLHQFFRDIADEESWIKEKKLLVGSDDYGRDLTGV 1746
Query: 2016 QNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIR 1837
QNL++KH+R++ ELASHEP + V+ GE+L+ + +G +I++R++ L Q+W +++
Sbjct: 1747 QNLKKKHKRLEAELASHEPAIQAVQEAGEKLMDVS---NLGVPEIEQRLKALNQAWTELK 1803
Query: 1836 DLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQ 1657
L R Q+LDES +Q FL VEEEEAW+ EKQQ+L +++G++MA VQGL+KKHD F+
Sbjct: 1804 GLAATRGQKLDESLIYQQFLAKVEEEEAWITEKQQLLSVEDYGDSMAAVQGLMKKHDAFE 1863
Query: 1656 VDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNS 1477
D +H+ R +D+ + G TL+ N NHH I QRC QL +L ++++A R L DN
Sbjct: 1864 TDFAVHRDRCSDIRDHGQTLVTNNNHHGDSISQRCVQLDKKLENLQALATRRKTALMDNF 1923
Query: 1476 AYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRI 1297
AYLQFMWK DVVESWIA+KE V+SE+FGRDLS+VQ LLTKQE FDAGL+AFEHEGI I
Sbjct: 1924 AYLQFMWKADVVESWIADKENHVKSEEFGRDLSTVQTLLTKQETFDAGLSAFEHEGIHNI 1983
Query: 1296 TELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAF 1117
T LKDQL+++ H QS AI KRH +V+ RWQ L A SEAR+ QIE+LYL F
Sbjct: 1984 TALKDQLINANHAQSAAILKRHEDVLTRWQKLRADSEARKYRLLNMQDQFRQIEDLYLTF 2043
Query: 1116 AKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRR 937
AKKAS FNSWFENAEEDLTDPVRCNS+EEI+ALR+AH FQ SLSSA+ DF+ L LD++
Sbjct: 2044 AKKASAFNSWFENAEEDLTDPVRCNSIEEIKALREAHAAFQASLSSAQVDFQALAALDQK 2103
Query: 936 IKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLANA 757
IKSFNVGPNPYTWFTM+ALEDTWRNLQ+II+ER+ ELA+E RQEENDKLR+EFAK AN
Sbjct: 2104 IKSFNVGPNPYTWFTMEALEDTWRNLQKIIEERDAELAKEVHRQEENDKLRKEFAKHANL 2163
Query: 756 FHAWLTNTRQEMMEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERNLILDNRY 577
FH WLT TR +M+ G+LEEQ +A+ KA EI+A +G L++IEE GA LE +LILDNRY
Sbjct: 2164 FHQWLTETRTSLMDGSGSLEEQFEALCHKANEIRARRGDLKKIEELGATLEEHLILDNRY 2223
Query: 576 TEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMMFKHFDKEKTGR 397
TEHSTVG+AQ WDQLDQLAMRMQHNL+QQIQARNQSGVSE++L+EFSMMFKHFDK+K+G+
Sbjct: 2224 TEHSTVGLAQQWDQLDQLAMRMQHNLKQQIQARNQSGVSEDSLKEFSMMFKHFDKDKSGK 2283
Query: 396 LDHQQFKSCLRALGYDLPMVDEGQPEPEFQRILDIVDPNRDGYVTLQEYMAFMISKETEN 217
L+HQ+FKSCLRALGYDLPMV+EGQP+PEF+ IL++VDPNRDG V+LQEY+AFMISKETEN
Sbjct: 2284 LNHQEFKSCLRALGYDLPMVEEGQPDPEFEEILNVVDPNRDGQVSLQEYIAFMISKETEN 2343
Query: 216 IQSSEEIEMAFRALSKEF---RPYVTAEELYANLTPEQAEFCIRRMKPYMDAISGRSIQG 46
+QS EEIE AFRA++ RPYVT EELY+NLT + A++C++RMKPY D +G I G
Sbjct: 2344 VQSFEEIENAFRAITASDPRPRPYVTKEELYSNLTKDMADYCVQRMKPYNDPKTGHPITG 2403
Query: 45 GLDYEQFVHALFQS 4
LDY +F LFQ+
Sbjct: 2404 ALDYVEFTRTLFQN 2417
>gi|17136504|ref|NP_476739.1| CG1977-PA [Drosophila melanogaster]
gi|14424461|sp|P13395|SPCA_DROME Spectrin alpha chain
gi|7292157|gb|AAF47569.1| CG1977-PA [Drosophila melanogaster]
Length = 2415
Score = 3030 bits (7855), Expect = 0.0
Identities = 1498/2412 (62%), Positives = 1870/2412 (77%), Gaps = 5/2412 (0%)
Frame = -1
Query: 7224 QEIRILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEK 7045
+E++ILET +DI +RR++VL Y+ FK ++ KR++LE++R+FQYFKRDADEL WI EK
Sbjct: 7 KEVKILETVEDIQERREQVLSRYNDFKIETRQKREKLEDSRRFQYFKRDADELESWIHEK 66
Query: 7044 LQTAQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKR 6865
LQ A EE++RDP+NLQAKIQKH+AFEAEV AH+ I +LD TG MI HFASE I+ R
Sbjct: 67 LQAASEESYRDPTNLQAKIQKHQAFEAEVSAHSNAIVSLDNTGQEMINQQHFASESIQVR 126
Query: 6864 LEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEH 6685
L+ELH LW KG+KLQQAL L+ F+RQC+E+++WI++KET+VTA++ G DLEH
Sbjct: 127 LDELHKLWELLLSRLAEKGLKLQQALVLVQFLRQCEEVMFWIKDKETFVTADEFGQDLEH 186
Query: 6684 VEILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTL 6505
VE+LQRKFD+F K++ + +YR+ E+NQ ADKLV++GH E D I K+++++N+AW RL L
Sbjct: 187 VEVLQRKFDEFQKDMASQEYRVTEVNQLADKLVQDGHPERDTITKRKEELNEAWQRLKQL 246
Query: 6504 AATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERD 6325
A R+E LFGAH++QRFNRDADET+AWI EKD+ LSSDDYGRDL +VQALQRKHEG ERD
Sbjct: 247 AIVRQEKLFGAHEIQRFNRDADETVAWIAEKDVVLSSDDYGRDLASVQALQRKHEGVERD 306
Query: 6324 LAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQL 6145
LAALE K+ L EA +L H D ++ I K + W +L KA+ RK L+ S+ L
Sbjct: 307 LAALEDKVSTLGAEAQRLCSIHADHSDQIRDKQAEIANYWQSLTTKARERKQKLDESYYL 366
Query: 6144 HRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASA 5965
HRFLAD+RDL+SWI MKA+I ADELAKDVAGAEALLE HQEHKGEIDAR DSF T +
Sbjct: 367 HRFLADFRDLVSWINGMKAIISADELAKDVAGAEALLERHQEHKGEIDAREDSFKLTTES 426
Query: 5964 GQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWM 5785
GQKL+E + E+QEKL L+++KSSLL LWE+RRILYEQCMDLQLFYRDTEQA+TWM
Sbjct: 427 GQKLLEREHYAAAEIQEKLAALENDKSSLLSLWEDRRILYEQCMDLQLFYRDTEQADTWM 486
Query: 5784 NKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADD 5605
KQEAFLAN DLGDSLDSVE LIKKHEDFEKSLAAQEEKI ALD FATKLI GQHYAADD
Sbjct: 487 AKQEAFLANEDLGDSLDSVEALIKKHEDFEKSLAAQEEKIKALDIFATKLIDGQHYAADD 546
Query: 5604 VAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLD 5425
VA+ R L++S + Q F+RDCDE WI+EKL A DDSYLD
Sbjct: 547 VAQRRQMLLARRAALQEKSSKRRQLLEDSNRYQQFERDCDETKGWISEKLKFATDDSYLD 606
Query: 5424 PTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNEL 5245
PTN+ GK+QKH NFE EL AN++R++DI + G ++I+ H+AAD I R++++ LW L
Sbjct: 607 PTNLNGKMQKHQNFEHELNANKSRIEDITNVGTELIEKQHYAADQINTRMQEIVVLWETL 666
Query: 5244 VDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLI 5065
V A++KKG KL EA +QQFNR IED+E WLSE+EGQ+ SED+GKDL SVQNLQKK L+
Sbjct: 667 VQASDKKGTKLNEACQQQQFNRTIEDIELWLSEIEGQLLSEDHGKDLTSVQNLQKKHALL 726
Query: 5064 ESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGES 4885
E+D AH DR++ IK A +F E HF+A I K+ NL RY AL P+ +RK+ L +S
Sbjct: 727 EADVMAHQDRIESIKVAANKFIESGHFDADNIRNKEGNLSARYAALAAPMGERKQHLLDS 786
Query: 4884 HQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESV 4705
Q QLFRD+EDE AWIREKE +A STNRGRDLIGVQNLIKK QA++AEI NH++++ +V
Sbjct: 787 LQVQQLFRDLEDEAAWIREKEPIAASTNRGRDLIGVQNLIKKHQAVLAEINNHEARLLNV 846
Query: 4704 SSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEAD 4525
S+ +M++ F + +IR +L L++ W LK K+ +R+ DLDDSLQAHQY +DANEA+
Sbjct: 847 ISSGENMLKDQPFASDDIRQRLEALQEQWNTLKEKSSQRKQDLDDSLQAHQYFADANEAE 906
Query: 4524 AWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQPM 4345
+WM EKEPI +DYGKDEDS+EALLKKH AL+SDLEAF TI+ L++QA C+ QE P+
Sbjct: 907 SWMREKEPIATGSDYGKDEDSSEALLKKHEALVSDLEAFGNTIQALQEQAKNCRQQETPV 966
Query: 4344 GQL-GRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKR 4168
+ G++CV+ALYDY EKSPREVSMKKGDVLTLLN++N+DWWKVEVNDRQGFVPAAY+K+
Sbjct: 967 VDITGKECVVALYDYTEKSPREVSMKKGDVLTLLNSNNKDWWKVEVNDRQGFVPAAYIKK 1026
Query: 4167 IEPG-TAQQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLA 3991
I+ G +A Q +SI +Q++I +Y L+ L R+ KL E K Y L+REA DLA
Sbjct: 1027 IDAGLSASQQNLVDNHSIAKRQNQINSQYDNLLALARERQNKLNETVKAYVLVREAADLA 1086
Query: 3990 EWIKSREAVAAQQEI-GTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQT 3814
+WI+ +E A ++ G DLE+VEVLQKKFDDF DLKANEVRL MN+IA LTS+GQT
Sbjct: 1087 QWIRDKENHAQIADVVGEDLEEVEVLQKKFDDFNDDLKANEVRLANMNEIAVQLTSLGQT 1146
Query: 3813 ETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDS 3634
E A++I+ Q++DLN +W L QLGSAHEVQRFHRD+DET+DWI EK +AL++
Sbjct: 1147 EAALKIQTQMQDLNEKWNNLQTLTAEKASQLGSAHEVQRFHRDIDETKDWIAEKANALNN 1206
Query: 3633 EDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELN 3454
+D G+DLRSVQ LQRKHEGVERDLAAL DKI+ LDE ANRL QSHP+ AEQ Y Q+E+N
Sbjct: 1207 DDLGKDLRSVQTLQRKHEGVERDLAALRDKIRQLDETANRLMQSHPDTAEQTYAKQKEIN 1266
Query: 3453 EQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALL 3274
E W+++ +K+ RKEKLLDSYD QRFLSDYRDL+ WI SM LV+S ELANDVTGAEAL+
Sbjct: 1267 EMWDQIITKSTARKEKLLDSYDLQRFLSDYRDLLAWINSMMSLVTSDELANDVTGAEALI 1326
Query: 3273 ERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARR 3094
ERHQE+RTEID+RA TF AF+QFGN+LL ++HYA+ +I+ +++ + +AR+ LE AW RR
Sbjct: 1327 ERHQEHRTEIDARAGTFGAFEQFGNELLQANHYASPEIKEKIEDLAKAREDLEKAWTERR 1386
Query: 3093 NILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPS--GDNVESLIKKHEDFDKAINTQE 2920
L+Q L+LQL+ RDCE A++WMSAREAFL +D + G NVE+LIKKHEDFDKAIN E
Sbjct: 1387 LQLEQNLDLQLYMRDCELAESWMSAREAFLNADDDANAGGNVEALIKKHEDFDKAINGHE 1446
Query: 2919 EKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSR 2740
+KI L+ A+ LI NHY S V KR Q+L+RW LKE LI+KR +LG+ QTLQQFSR
Sbjct: 1447 QKIAALQTVADQLIAQNHYASNLVDEKRKQVLERWRHLKEGLIEKRSRLGDEQTLQQFSR 1506
Query: 2739 DADEIENWMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIE 2560
DADEIENW+ EK Q+A EE+Y+DP NIQ KHQK QAFEAEL AN+DRI +++ G NLI+
Sbjct: 1507 DADEIENWIAEKLQLATEESYKDPANIQSKHQKHQAFEAELAANADRIQSVLAMGGNLID 1566
Query: 2559 NAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVE 2380
+C G E AV RL + DQW+ L TTEKS +LKEANKQ++++AAVKDL+FWLGEVE
Sbjct: 1567 KKQCSGSEDAVQKRLTQIADQWEYLTHKTTEKSLKLKEANKQRTYIAAVKDLDFWLGEVE 1626
Query: 2379 ILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAER 2200
LL +ED GKDLASV+NL+KKH L+EADIVAH+DR+ +MN QADSL+E+ QF I E+
Sbjct: 1627 SLLTTEDSGKDLASVQNLMKKHQLVEADIVAHEDRIKDMNNQADSLVESGQFDTAGIQEK 1686
Query: 2199 RKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPG 2020
R+ I +RY+ + +A R+ +L++AL +HQFFRDI DEESWIKEKKLLV SDDYGRDL G
Sbjct: 1687 RQSINERYERICNLAAHRQARLNEALTLHQFFRDIADEESWIKEKKLLVGSDDYGRDLTG 1746
Query: 2019 VQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQI 1840
VQNL++KH+R++ EL SHEP + V+ GE+L+ + +G +I++R++ L Q+W ++
Sbjct: 1747 VQNLKKKHKRLEAELGSHEPAIQAVQEAGEKLMDVS---NLGVPEIEQRLKALNQAWAEL 1803
Query: 1839 RDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTF 1660
++L R Q+LDES +Q FL VEEEEAW+ EKQQ+L +++G++MA VQGLLKKHD F
Sbjct: 1804 KNLAATRGQKLDESLTYQQFLAQVEEEEAWITEKQQLLSVEDYGDSMAAVQGLLKKHDAF 1863
Query: 1659 QVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDN 1480
+ D HK R + + ++G L+ NHH I QRC QLR +L + ++A R L DN
Sbjct: 1864 ETDFTAHKDRCSLICDQGSELVEAKNHHGESIAQRCQQLRLKLDNLSALAARRKGALLDN 1923
Query: 1479 SAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQR 1300
SAYLQFMWK DVVESWI +KE VRS++FGRDLS+VQ LLTKQE FDAGLNAFE EGI
Sbjct: 1924 SAYLQFMWKADVVESWIDDKENYVRSDEFGRDLSTVQTLLTKQETFDAGLNAFEQEGIHN 1983
Query: 1299 ITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLA 1120
IT LKDQL+++ H QSPAI KRH +VI RWQ L S R+ QIEELYL
Sbjct: 1984 ITALKDQLINASHAQSPAILKRHGDVIARWQKLRDASNTRKDRLLAMQEQFRQIEELYLT 2043
Query: 1119 FAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDR 940
FAKKAS FNSWFENAEEDLTDPVRCNS+EEIRALRDAH +FQ SLSSAE DF+ L LD+
Sbjct: 2044 FAKKASAFNSWFENAEEDLTDPVRCNSIEEIRALRDAHAQFQASLSSAEADFKALAALDQ 2103
Query: 939 RIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLAN 760
+IKSFNVGPNPYTWFTM+ALE+TWRNLQ+II+ER+ ELA+E +RQEENDKLR+EFAK AN
Sbjct: 2104 KIKSFNVGPNPYTWFTMEALEETWRNLQKIIEERDGELAKEAKRQEENDKLRKEFAKHAN 2163
Query: 759 AFHAWLTNTRQEMMEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERNLILDNR 580
FH WLT TR MME G+LE+QL+A+ KA E++A + L++IEE GA+LE +LILDNR
Sbjct: 2164 LFHQWLTETRTSMMEGSGSLEQQLEALRVKATEVRARRVDLKKIEELGALLEEHLILDNR 2223
Query: 579 YTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMMFKHFDKEKTG 400
YTEHSTVG+AQ WDQLDQL+MRMQHNLEQQIQARN SGVSE++L+EFSMMFKHFDK+K+G
Sbjct: 2224 YTEHSTVGLAQQWDQLDQLSMRMQHNLEQQIQARNHSGVSEDSLKEFSMMFKHFDKDKSG 2283
Query: 399 RLDHQQFKSCLRALGYDLPMVDEGQPEPEFQRILDIVDPNRDGYVTLQEYMAFMISKETE 220
+L+HQ+FKSCLRALGYDLPMV+EGQP+PEF+ ILD+VDPNRDGYV+LQEY+AFMISKETE
Sbjct: 2284 KLNHQEFKSCLRALGYDLPMVEEGQPDPEFEAILDVVDPNRDGYVSLQEYIAFMISKETE 2343
Query: 219 NIQSSEEIEMAFRALSKEFRPYVTAEELYANLTPEQAEFCIRRMKPYMDAISGRSIQGGL 40
N+QS EEIE AFRA++ RPYVT EELY NLT + A++C++RMKP+ + SG+ I+ L
Sbjct: 2344 NVQSYEEIENAFRAITAADRPYVTKEELYCNLTKDMADYCVQRMKPFSEPRSGQPIKDAL 2403
Query: 39 DYEQFVHALFQS 4
DY F LFQ+
Sbjct: 2404 DYIDFTRTLFQN 2415
>gi|103399|pir||A33733 spectrin alpha chain - fruit fly (Drosophila
melanogaster)
gi|158489|gb|AAA28907.1| alpha-spectrin
Length = 2415
Score = 3028 bits (7851), Expect = 0.0
Identities = 1497/2412 (62%), Positives = 1870/2412 (77%), Gaps = 5/2412 (0%)
Frame = -1
Query: 7224 QEIRILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEK 7045
+E++ILET +DI +RR++VL Y+ FK ++ KR++LE++R+FQYFKRDADEL WI EK
Sbjct: 7 KEVKILETVEDIQERREQVLSRYNDFKIETRQKREKLEDSRRFQYFKRDADELESWIHEK 66
Query: 7044 LQTAQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKR 6865
LQ A EE++RDP+NLQAKIQKH+AFEAEV AH+ I +LD TG MI HFASE I+ R
Sbjct: 67 LQAASEESYRDPTNLQAKIQKHQAFEAEVSAHSNAIVSLDNTGQEMINQQHFASESIQVR 126
Query: 6864 LEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEH 6685
L+ELH LW KG+KLQQAL L+ F+RQC+E+++WI++KET+VTA++ G DLEH
Sbjct: 127 LDELHKLWELLLSRLAEKGLKLQQALVLVQFLRQCEEVMFWIKDKETFVTADEFGQDLEH 186
Query: 6684 VEILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTL 6505
VE+LQRKFD+F K++ + +YR+ E+NQ ADKLV++GH E D I K+++++N+AW RL L
Sbjct: 187 VEVLQRKFDEFQKDMASQEYRVTEVNQLADKLVQDGHPERDTITKRKEELNEAWQRLKQL 246
Query: 6504 AATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERD 6325
A R+E LFGAH++QRFNRDADET+AWI EKD+ LSSDDYGRDL +VQALQRKHEG ERD
Sbjct: 247 AIVRQEKLFGAHEIQRFNRDADETVAWIAEKDVVLSSDDYGRDLASVQALQRKHEGVERD 306
Query: 6324 LAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQL 6145
LAALE K+ L EA +L H D ++ I K + W +L KA+ RK L+ S+ L
Sbjct: 307 LAALEDKVSTLGAEAQRLCSIHADHSDQIRDKQAEIANYWQSLTTKARERKQKLDESYYL 366
Query: 6144 HRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASA 5965
HRFLAD+RDL+SWI MKA+I ADELAKDVAGAEALLE HQEHKGEIDAR DSF T +
Sbjct: 367 HRFLADFRDLVSWINGMKAIISADELAKDVAGAEALLERHQEHKGEIDAREDSFKLTTES 426
Query: 5964 GQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWM 5785
GQKL+E + E+QEKL L+++KSSLL LWE+RRILYEQCMDLQLFYRDTEQA+TWM
Sbjct: 427 GQKLLEREHYAAAEIQEKLAALENDKSSLLSLWEDRRILYEQCMDLQLFYRDTEQADTWM 486
Query: 5784 NKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADD 5605
KQEAFLAN DLGDSLDSVE LIKKHEDFEKSLAAQEEKI ALD FATKLI GQHYAADD
Sbjct: 487 AKQEAFLANEDLGDSLDSVEALIKKHEDFEKSLAAQEEKIKALDIFATKLIDGQHYAADD 546
Query: 5604 VAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLD 5425
VA+ R L++S + Q F+RDCDE WI+EKL A DDSYLD
Sbjct: 547 VAQRRQMLLARRAALQEKSSKRRQLLEDSNRYQQFERDCDETKGWISEKLKFATDDSYLD 606
Query: 5424 PTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNEL 5245
PTN+ GK+QKH NFE EL AN++R++DI + G ++I+ H+AAD I R++++ LW L
Sbjct: 607 PTNLNGKMQKHQNFEHELNANKSRIEDITNVGTELIEKQHYAADQINTRMQEIVVLWETL 666
Query: 5244 VDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLI 5065
V A++KKG KL EA +QQFNR IED+E WLSE+EGQ+ SED+GKDL SVQNLQKK L+
Sbjct: 667 VQASDKKGTKLNEACQQQQFNRTIEDIELWLSEIEGQLLSEDHGKDLTSVQNLQKKHALL 726
Query: 5064 ESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGES 4885
E+D AH DR++ IK A +F E HF+A I K+ NL RY AL P+ +RK+ L +S
Sbjct: 727 EADVMAHQDRIESIKVAANKFIESGHFDADNIRNKEGNLSARYAALAAPMGERKQHLLDS 786
Query: 4884 HQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESV 4705
Q QLFRD+EDE AWIREKE +A STNRGRDLIGVQNLIKK QA++AEI NH++++ +V
Sbjct: 787 LQVQQLFRDLEDEAAWIREKEPIAASTNRGRDLIGVQNLIKKHQAVLAEINNHEARLLNV 846
Query: 4704 SSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEAD 4525
S+ +M++ F + +IR +L L++ W LK K+ +R+ DLDDSLQAHQY +DANEA+
Sbjct: 847 ISSGENMLKDQPFASDDIRQRLEALQEQWNTLKEKSSQRKQDLDDSLQAHQYFADANEAE 906
Query: 4524 AWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQPM 4345
+WM EKEPI +DYGKDEDS+EALLKKH AL+SDLEAF TI+ L++QA C+ QE P+
Sbjct: 907 SWMREKEPIATGSDYGKDEDSSEALLKKHEALVSDLEAFGNTIQALQEQAKNCRQQETPV 966
Query: 4344 GQL-GRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKR 4168
+ G++CV+ALYDY EKSPREVSMKKGDVLTLLN++N+DWWKVEVNDRQGFVPAAY+K+
Sbjct: 967 VDITGKECVVALYDYTEKSPREVSMKKGDVLTLLNSNNKDWWKVEVNDRQGFVPAAYIKK 1026
Query: 4167 IEPG-TAQQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLA 3991
I+ G +A Q +SI +Q++I +Y L+ L R+ KL E K Y L+REA DLA
Sbjct: 1027 IDAGLSASQQNLVDNHSIAKRQNQINSQYDNLLALARERQNKLNETVKAYVLVREAADLA 1086
Query: 3990 EWIKSREAVAAQQEI-GTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQT 3814
+WI+ +E A ++ G DLE+VEVLQKKFDDF DLKANEVRL MN+IA LTS+GQT
Sbjct: 1087 QWIRDKENHAQIADVVGEDLEEVEVLQKKFDDFNDDLKANEVRLANMNEIAVQLTSLGQT 1146
Query: 3813 ETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDS 3634
E A++I+ Q++DLN +W L QLGSAHEVQRFHRD+DET+DWI EK +AL++
Sbjct: 1147 EAALKIQTQMQDLNEKWNNLQTLTAEKASQLGSAHEVQRFHRDIDETKDWIAEKANALNN 1206
Query: 3633 EDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELN 3454
+D G+DLRSVQ LQRKHEGVERDLAAL DKI+ LDE ANRL QSHP+ AEQ Y Q+E+N
Sbjct: 1207 DDLGKDLRSVQTLQRKHEGVERDLAALRDKIRQLDETANRLMQSHPDTAEQTYAKQKEIN 1266
Query: 3453 EQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALL 3274
E W+++ +K+ RKEKLLDSYD QRFLSDYRDL+ WI SM LV+S ELANDVTGAEAL+
Sbjct: 1267 EMWDQIITKSTARKEKLLDSYDLQRFLSDYRDLLAWINSMMSLVTSDELANDVTGAEALI 1326
Query: 3273 ERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARR 3094
ERHQE+RTEID+RA TF AF+QFGN+LL ++HYA+ +I+ +++ + +AR+ LE AW RR
Sbjct: 1327 ERHQEHRTEIDARAGTFGAFEQFGNELLQANHYASPEIKEKIEDLAKAREDLEKAWTERR 1386
Query: 3093 NILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPS--GDNVESLIKKHEDFDKAINTQE 2920
L+Q L+LQL+ RDCE A++WMSAREAFL +D + G NVE+LIKKHEDFDKAIN E
Sbjct: 1387 LQLEQNLDLQLYMRDCELAESWMSAREAFLNADDDANAGGNVEALIKKHEDFDKAINGHE 1446
Query: 2919 EKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSR 2740
+KI L+ A+ LI NHY S V KR Q+L+RW LKE LI+KR +LG+ QTLQQFSR
Sbjct: 1447 QKIAALQTVADQLIAQNHYASNLVDEKRKQVLERWRHLKEGLIEKRSRLGDEQTLQQFSR 1506
Query: 2739 DADEIENWMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIE 2560
DADEIENW+ EK Q+A EE+Y+DP NIQ KHQK QAFEAEL AN+DRI +++ G NLI+
Sbjct: 1507 DADEIENWIAEKLQLATEESYKDPANIQSKHQKHQAFEAELAANADRIQSVLAMGGNLID 1566
Query: 2559 NAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVE 2380
+C G E AV RL + DQW+ L TTEKS +LKEANKQ++++AAVKDL+FWLGEVE
Sbjct: 1567 KKQCSGSEDAVQKRLTQIADQWEYLTHKTTEKSLKLKEANKQRTYIAAVKDLDFWLGEVE 1626
Query: 2379 ILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAER 2200
LL +ED GKDLASV+NL+KKH L+EADIVAH+DR+ +MN +ADSL+E+ QF I E+
Sbjct: 1627 SLLTTEDSGKDLASVQNLMKKHQLVEADIVAHEDRIKDMNNRADSLVESGQFDTAGIQEK 1686
Query: 2199 RKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPG 2020
R+ I +RY+ + +A R+ +L++AL +HQFFRDI DEESWIKEKKLLV SDDYGRDL G
Sbjct: 1687 RQSINERYERICNLAAHRQARLNEALTLHQFFRDIADEESWIKEKKLLVGSDDYGRDLTG 1746
Query: 2019 VQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQI 1840
VQNL++KH+R++ EL SHEP + V+ GE+L+ + +G +I++R++ L Q+W ++
Sbjct: 1747 VQNLKKKHKRLEAELGSHEPAIQAVQEAGEKLMDVS---NLGVPEIEQRLKALNQAWAEL 1803
Query: 1839 RDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTF 1660
++L R Q+LDES +Q FL VEEEEAW+ EKQQ+L +++G++MA VQGLLKKHD F
Sbjct: 1804 KNLAATRGQKLDESLTYQQFLAQVEEEEAWITEKQQLLSVEDYGDSMAAVQGLLKKHDAF 1863
Query: 1659 QVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDN 1480
+ D HK R + + ++G L+ NHH I QRC QLR +L + ++A R L DN
Sbjct: 1864 ETDFTAHKDRCSLICDQGSELVEAKNHHGESIAQRCQQLRLKLDNLSALAARRKGALLDN 1923
Query: 1479 SAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQR 1300
SAYLQFMWK DVVESWI +KE VRS++FGRDLS+VQ LLTKQE FDAGLNAFE EGI
Sbjct: 1924 SAYLQFMWKADVVESWIDDKENYVRSDEFGRDLSTVQTLLTKQETFDAGLNAFEQEGIHN 1983
Query: 1299 ITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLA 1120
IT LKDQL+++ H QSPAI KRH +VI RWQ L S R+ QIEELYL
Sbjct: 1984 ITALKDQLINASHAQSPAILKRHGDVIARWQKLRDASNTRKDRLLAMQEQFRQIEELYLT 2043
Query: 1119 FAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDR 940
FAKKAS FNSWFENAEEDLTDPVRCNS+EEIRALRDAH +FQ SLSSAE DF+ L LD+
Sbjct: 2044 FAKKASAFNSWFENAEEDLTDPVRCNSIEEIRALRDAHAQFQASLSSAEADFKALAALDQ 2103
Query: 939 RIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLAN 760
+IKSFNVGPNPYTWFTM+ALE+TWRNLQ+II+ER+ ELA+E +RQEENDKLR+EFAK AN
Sbjct: 2104 KIKSFNVGPNPYTWFTMEALEETWRNLQKIIEERDGELAKEAKRQEENDKLRKEFAKHAN 2163
Query: 759 AFHAWLTNTRQEMMEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERNLILDNR 580
FH WLT TR MME G+LE+QL+A+ KA E++A + L++IEE GA+LE +LILDNR
Sbjct: 2164 LFHQWLTETRTSMMEGSGSLEQQLEALRVKATEVRARRVDLKKIEELGALLEEHLILDNR 2223
Query: 579 YTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMMFKHFDKEKTG 400
YTEHSTVG+AQ WDQLDQL+MRMQHNLEQQIQARN SGVSE++L+EFSMMFKHFDK+K+G
Sbjct: 2224 YTEHSTVGLAQQWDQLDQLSMRMQHNLEQQIQARNHSGVSEDSLKEFSMMFKHFDKDKSG 2283
Query: 399 RLDHQQFKSCLRALGYDLPMVDEGQPEPEFQRILDIVDPNRDGYVTLQEYMAFMISKETE 220
+L+HQ+FKSCLRALGYDLPMV+EGQP+PEF+ ILD+VDPNRDGYV+LQEY+AFMISKETE
Sbjct: 2284 KLNHQEFKSCLRALGYDLPMVEEGQPDPEFEAILDVVDPNRDGYVSLQEYIAFMISKETE 2343
Query: 219 NIQSSEEIEMAFRALSKEFRPYVTAEELYANLTPEQAEFCIRRMKPYMDAISGRSIQGGL 40
N+QS EEIE AFRA++ RPYVT EELY NLT + A++C++RMKP+ + SG+ I+ L
Sbjct: 2344 NVQSYEEIENAFRAITAADRPYVTKEELYCNLTKDMADYCVQRMKPFSEPRSGQPIKDAL 2403
Query: 39 DYEQFVHALFQS 4
DY F LFQ+
Sbjct: 2404 DYIDFTRTLFQN 2415
>gi|47477769|gb|AAH70885.1| Spna2 protein [Rattus norvegicus]
Length = 2452
Score = 2854 bits (7399), Expect = 0.0
Identities = 1423/2449 (58%), Positives = 1818/2449 (74%), Gaps = 46/2449 (1%)
Frame = -1
Query: 7218 IRILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQ 7039
+++LETA+DI +RRQ+VL Y FK+ S +R +LE++ +FQ+F+RDA+EL WI EKLQ
Sbjct: 6 VKVLETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQ 65
Query: 7038 TAQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLE 6859
A +EN++DP+NLQ K+QKH+AFEAEVQA++ I LD+TGN MI HFASE I+ RL
Sbjct: 66 VASDENYKDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLM 125
Query: 6858 ELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVE 6679
ELH W KGIKL QA KL+ ++R+C++++ WI +KE VT+E++G DLEHVE
Sbjct: 126 ELHRQWELLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVE 185
Query: 6678 ILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAA 6499
+LQ+KF++F +L H+ R+NE+NQ A KL++E H E + I K+++VN AW RL LA
Sbjct: 186 VLQKKFEEFQTDLAAHEERVNEVNQFAAKLIQEQHPEEELIKTKQEEVNAAWQRLKGLAL 245
Query: 6498 TRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLA 6319
R+ LFGA +VQRFNRD DET+ WI EK+ ++SDD+GRDL +VQAL RKHEG ERDLA
Sbjct: 246 QRQGKLFGAAEVQRFNRDVDETIGWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLA 305
Query: 6318 ALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHR 6139
ALE K+ L EA +L ++HP A I K ++ W ++ A R L+ S++L R
Sbjct: 306 ALEDKVKALCAEADRLQQSHPLSANQIQVKREELITNWEQIRTLAAERHARLDDSYRLQR 365
Query: 6138 FLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQ 5959
FLAD+RDL SW+ +MKA+I ADELA DVAGAEALL+ HQEHKGEIDA DSF +GQ
Sbjct: 366 FLADFRDLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQ 425
Query: 5958 KLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNK 5779
L+ G S EV+EKL L E+++LL LWE RR YEQCMDLQLFYRDTEQ + WM+K
Sbjct: 426 ALLAAGHYASDEVREKLSILSEERAALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSK 485
Query: 5778 QEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVA 5599
QEAFL N DLGDSLDSVE L+KKHEDFEKSL+AQEEKI ALDEFATKLIQ HYA +DVA
Sbjct: 486 QEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMEDVA 545
Query: 5598 EXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPT 5419
R L +S+ Q F RD DE+ SW+ EK+ TA D++Y DP+
Sbjct: 546 TRRDALLSRRNALHERAMHRRAQLADSFHLQQFFRDSDELKSWVNEKMKTATDEAYKDPS 605
Query: 5418 NIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVD 5239
N++GK+QKH FE EL AN++R+D + G+++ID H+A + + R+ +V +LW +L++
Sbjct: 606 NLQGKVQKHQAFEAELSANQSRIDALEKAGQKLIDVNHYAKEEVAARMNEVISLWKKLLE 665
Query: 5238 ATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIES 5059
AT KG KLREA +QQFNRN+ED+E WL E+EG +AS+DYGKDL +VQNLQKK L+E+
Sbjct: 666 ATELKGVKLREANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTNVQNLQKKHALLEA 725
Query: 5058 DFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQ 4879
D AH DR+DGI A+QFQ+ HF+A I +KQE L RY AL++P+ RK+KL +S +
Sbjct: 726 DVAAHQDRIDGITIQARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKLADSLR 785
Query: 4878 GNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSS 4699
QLFRD+EDE WIREKE +A STNRG+DLIGVQNL+KK QAL AEIA H+ +I++V+
Sbjct: 786 LQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQ 845
Query: 4698 AANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAW 4519
N M+++GHF A +++ KL++L W LK+KA +RR DL+DSLQA QY +DANEA++W
Sbjct: 846 KGNAMVEEGHFAAEDVKAKLSELNQKWEALKAKASQRRQDLEDSLQAQQYFADANEAESW 905
Query: 4518 MSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQPM-G 4342
M EKEPIVGSTDYGKDEDSAEALLKKH AL+SDL A+ +I+ LR+QA C+ Q PM
Sbjct: 906 MREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPMDD 965
Query: 4341 QLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIE 4162
+ G++ VLALYDYQEKSPREV+MKKGD+LTLLN++N+DWWKVEVNDRQGFVPAAYVK+++
Sbjct: 966 ETGKELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVKKLD 1025
Query: 4161 P--GTAQQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAE 3988
P ++++ ++ SI +Q +I+++YQ L+ LGE RK LE++CK + L REAN+L +
Sbjct: 1026 PAQSASRENLLEEQGSIALRQGQIDNQYQSLLELGEKRKGMLEKSCKKFMLFREANELQQ 1085
Query: 3987 WIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTET 3808
WI +EA +E+G DLEQVEVLQKKFDDF+ DLKANE RL+++N++A L S G
Sbjct: 1086 WINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAE 1145
Query: 3807 AVRIRQQ-----------------------------------IEDLNARWRALXXXXXXX 3733
V+ QQ I++LN RWR+L
Sbjct: 1146 EVQAVQQQEVYGMMPRDEADSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEER 1205
Query: 3732 XXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAAL 3553
LGSAHEVQRFHRD DET++WI+EK+ AL+++++G DL SVQALQRKHEG ERDLAAL
Sbjct: 1206 SQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAAL 1265
Query: 3552 GDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFL 3373
GDK+ SL E A RL QSHPE+AE + + ELN+ W L +A+ RK KL DS+D QRFL
Sbjct: 1266 GDKVNSLGETAQRLIQSHPESAEDLKEKCTELNQAWTSLGKRADQRKAKLGDSHDLQRFL 1325
Query: 3372 SDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQL 3193
SD+RDLM WI + LVSS ELA DVTGAEALLERHQE+RTEID+RA TFQAF+QFG QL
Sbjct: 1326 SDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQL 1385
Query: 3192 LNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSARE 3013
L HYA+ +I+ +L +++ R LE AWV RR +LD CLELQLF+RDCEQA+ WM+ARE
Sbjct: 1386 LAHGHYASPEIKEKLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWMAARE 1445
Query: 3012 AFLAQED--PSGDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRK 2839
AFL ED S D+VE+LIKKHEDFDKAIN QEEKI L+ FA+ LI +HY + +
Sbjct: 1446 AFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAVDHYAKGDIANR 1505
Query: 2838 RDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNI 2659
R+++LDRW LK +I+KR KLGESQTLQQFSRD DEIE W++EK Q A +E+Y+DPTNI
Sbjct: 1506 RNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPTNI 1565
Query: 2658 QQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVK 2479
Q KHQK QAFEAELHAN+DRI +I GN+LIE C G E AV ARL AL DQW LV+
Sbjct: 1566 QSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQFLVQ 1625
Query: 2478 TTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEA 2299
+ EKS +LKEANKQ++F +KD +FWL EVE LL SEDYGKDLASV NLLKKH LLEA
Sbjct: 1626 KSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQLLEA 1685
Query: 2298 DIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALN 2119
DI AH+DR+ ++N QADSL+ + F Q+ E+R I R+ +K MAT RR KLS++
Sbjct: 1686 DISAHEDRLKDLNSQADSLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKLSESHR 1745
Query: 2118 VHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKL 1939
+HQFFRD+DDEESWIKEKKLLVSS+DYGRDL GVQNLR+KH+R++ ELA+HEP + V
Sbjct: 1746 LHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLD 1805
Query: 1938 KGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEE 1759
G++L + + +G+++I++R+ + W +++ L R QRL+ES +Q F+ +VEEE
Sbjct: 1806 TGKKL---SDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEE 1862
Query: 1758 EAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNH 1579
EAW+NEK ++ S+++G+ +A +QGLLKKH+ F+ D +HK RV D+ G LI NH
Sbjct: 1863 EAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNH 1922
Query: 1578 HAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSE 1399
H +I + L ++ ++E A R AKL +NSA+LQF WK DVVESWI EKE ++++
Sbjct: 1923 HEENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTD 1982
Query: 1398 DFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVI 1219
D+GRDLSSVQ LLTKQE FDAGL AF+ EGI IT LKDQL++++H QS AIE RH +++
Sbjct: 1983 DYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHASLM 2042
Query: 1218 QRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNS 1039
+RW LLA+S R+ ++E+L+L FAKKAS FNSWFENAEEDLTDPVRCNS
Sbjct: 2043 KRWTQLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNS 2102
Query: 1038 LEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNL 859
LEEI+ALR+AH F+ SLSSA+ DF QL +LDR+IKSF V NPYTWFTM+ALE+TWRNL
Sbjct: 2103 LEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFTMEALEETWRNL 2162
Query: 858 QRIIKEREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQE------MMEAGGTLE 697
Q+IIKERE EL +E +RQEENDKLR+EFA+ ANAFH W+ TR M+E GTLE
Sbjct: 2163 QKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRTYLLDGSCMVEESGTLE 2222
Query: 696 EQLDAVERKAKEIKANKGQLRQIEEKGAMLERNLILDNRYTEHSTVGIAQAWDQLDQLAM 517
QL+A +RK +EI+A + QL++IE+ GA +E LILDN+YTEHSTVG+AQ WDQLDQL M
Sbjct: 2223 SQLEATKRKHQEIRAMRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQQWDQLDQLGM 2282
Query: 516 RMQHNLEQQIQARNQSGVSEEALREFSMMFKHFDKEKTGRLDHQQFKSCLRALGYDLPMV 337
RMQHNLEQQIQARN +GV+EEAL+EFSMMFKHFDK+K+GRL+HQ+FKSCLR+LGYDLPMV
Sbjct: 2283 RMQHNLEQQIQARNTTGVTEEALKEFSMMFKHFDKDKSGRLNHQEFKSCLRSLGYDLPMV 2342
Query: 336 DEGQPEPEFQRILDIVDPNRDGYVTLQEYMAFMISKETENIQSSEEIEMAFRALSKEFRP 157
+EG+P+PEF+ ILD VDPNRDG+V+LQEYMAFMIS+ETEN++SSEEIE AFRALS E +P
Sbjct: 2343 EEGEPDPEFEAILDTVDPNRDGHVSLQEYMAFMISRETENVKSSEEIESAFRALSSEGKP 2402
Query: 156 YVTAEELYANLTPEQAEFCIRRMKPYMDAISGRSIQGGLDYEQFVHALF 10
YVT EELY NLT EQA++C+ MKPY+D GR + DY +F +LF
Sbjct: 2403 YVTKEELYQNLTREQADYCVSHMKPYVDG-KGRELPTAFDYVEFTRSLF 2450
>gi|31565122|gb|AAH53521.1| SPTAN1 protein [Homo sapiens]
Length = 2452
Score = 2848 bits (7384), Expect = 0.0
Identities = 1420/2449 (57%), Positives = 1816/2449 (73%), Gaps = 46/2449 (1%)
Frame = -1
Query: 7218 IRILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQ 7039
+++LETA+DI +RRQ+VL Y FK+ S +R +LE++ +FQ+F+RDA+EL WI EKLQ
Sbjct: 6 VKVLETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQ 65
Query: 7038 TAQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLE 6859
A +EN++DP+NLQ K+QKH+AFEAEVQA++ I LD+TGN MI HFASE I+ RL
Sbjct: 66 IASDENYKDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLM 125
Query: 6858 ELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVE 6679
ELH W KGIKL QA KL+ ++R+C++++ WI +KE VT+E++G DLEHVE
Sbjct: 126 ELHRQWELLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVE 185
Query: 6678 ILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAA 6499
+LQ+KF++F ++ H+ R+NE+NQ A KL++E H E + I K+D+VN AW RL LA
Sbjct: 186 VLQKKFEEFQTDMAAHEERVNEVNQFAAKLIQEQHPEEELIKTKQDEVNAAWQRLKGLAL 245
Query: 6498 TRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLA 6319
R+ LFGA +VQRFNRD DET++WI EK+ ++SDD+GRDL +VQAL RKHEG ERDLA
Sbjct: 246 QRQGKLFGAAEVQRFNRDVDETISWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLA 305
Query: 6318 ALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHR 6139
ALE K+ L EA +L ++HP A I K ++ W ++ A R L S++L R
Sbjct: 306 ALEDKVKALCAEADRLQQSHPLSATQIQVKREELITNWEQIRTLAAERHARLNDSYRLQR 365
Query: 6138 FLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQ 5959
FLAD+RDL SW+ +MKA+I ADELA DVAGAEALL+ HQEHKGEIDA DSF +GQ
Sbjct: 366 FLADFRDLTSWVTEMKALINADELASDVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQ 425
Query: 5958 KLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNK 5779
L+ G S EV+EKL L E+++LL LWE RR YEQCMDLQLFYRDTEQ + WM+K
Sbjct: 426 ALLAAGHYASDEVREKLTVLSEERAALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSK 485
Query: 5778 QEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVA 5599
QEAFL N DLGDSLDSVE L+KKHEDFEKSL+AQEEKI ALDEFATKLIQ HYA +DVA
Sbjct: 486 QEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMEDVA 545
Query: 5598 EXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPT 5419
R L +S+ Q F RD DE+ SW+ EK+ TA D++Y DP+
Sbjct: 546 TRRDALLSRRNALHERAMRRRAQLADSFHLQQFFRDSDELKSWVNEKMKTATDEAYKDPS 605
Query: 5418 NIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVD 5239
N++GK+QKH FE EL AN++R+D + G+++ID H+A D + R+ +V +LW +L++
Sbjct: 606 NLQGKVQKHQAFEAELSANQSRIDALEKAGQKLIDVNHYAKDEVAARMNEVISLWKKLLE 665
Query: 5238 ATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIES 5059
AT KG KLREA +QQFNRN+ED+E WL E+EG +AS+DYGKDL +VQNLQKK L+E+
Sbjct: 666 ATELKGIKLREANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTNVQNLQKKHALLEA 725
Query: 5058 DFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQ 4879
D AH DR+DGI A+QFQ+ HF+A I +KQE L RY AL++P+ RK+KL +S +
Sbjct: 726 DVAAHQDRIDGITIQARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKLADSLR 785
Query: 4878 GNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSS 4699
QLFRD+EDE WIREKE +A STNRG+DLIGVQNL+KK QAL AEIA H+ +I++V+
Sbjct: 786 LQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQ 845
Query: 4698 AANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAW 4519
N M+++GHF A +++ KL +L W LK+KA +RR DL+DSLQA QY +DANEA++W
Sbjct: 846 KGNAMVEEGHFAAEDVKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADANEAESW 905
Query: 4518 MSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQPMG- 4342
M EKEPIVGSTDYGKDEDSAEALLKKH AL+SDL A+ +I+ LR+QA C+ Q P
Sbjct: 906 MREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPTDD 965
Query: 4341 QLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIE 4162
+ G++ VLALYDYQEKSPREV+MKKGD+LTLLN++N+DWWKVEVNDRQGFVPAAYVK+++
Sbjct: 966 ETGKELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVKKLD 1025
Query: 4161 PG--TAQQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAE 3988
P ++++ ++ SI +Q +I+++Y L+ LGE RK LE++CK + L REAN+L +
Sbjct: 1026 PAQSASRENLLEEQGSIALRQEQIDNQYHSLLELGEKRKGMLEKSCKKFMLFREANELQQ 1085
Query: 3987 WIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTET 3808
WI +EA +E+G DLEQVEVLQKKFDDF+ DLKANE RL+++N++A L S G
Sbjct: 1086 WINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAE 1145
Query: 3807 AVRIRQQ-----------------------------------IEDLNARWRALXXXXXXX 3733
V+ QQ I++LN RWR+L
Sbjct: 1146 EVQAVQQQEVYGMMPRDETDSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEER 1205
Query: 3732 XXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAAL 3553
LGSAHEVQRFHRD DET++WI+EK+ AL+++++G DL SVQALQRKHEG ERDLAAL
Sbjct: 1206 SQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAAL 1265
Query: 3552 GDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFL 3373
GDK+ SL E A RL QSHPE+AE + + ELN+ W+ L +A+ RK KL DS+D QRFL
Sbjct: 1266 GDKVNSLGETAERLIQSHPESAEDLQEKCTELNQAWSSLGKRADQRKAKLGDSHDLQRFL 1325
Query: 3372 SDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQL 3193
SD+RDLM WI + LVSS ELA DVTGAEALLERHQE+RTEID+RA TFQAF+QFG QL
Sbjct: 1326 SDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQL 1385
Query: 3192 LNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSARE 3013
L HYA+ +I+ +L +++ R LE AWV RR +LDQCLELQLF+RDCEQA+ WM+ARE
Sbjct: 1386 LAHGHYASPEIKQKLDILDQERADLEKAWVQRRMMLDQCLELQLFHRDCEQAENWMAARE 1445
Query: 3012 AFLAQEDP--SGDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRK 2839
AFL ED S D+VE+LIKKHEDFDKAIN QEEKI L+ FA+ LI HY ++ +
Sbjct: 1446 AFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAAGHYAKGDISSR 1505
Query: 2838 RDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNI 2659
R+++LDRW LK +I+KR KLGESQTLQQFSRD DEIE W++EK Q A +E+Y+DPTNI
Sbjct: 1506 RNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPTNI 1565
Query: 2658 QQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVK 2479
Q KHQK QAFEAELHAN+DRI +I GN+LIE C G E AV ARL AL DQW LV+
Sbjct: 1566 QSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQFLVQ 1625
Query: 2478 TTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEA 2299
+ EKS +LKEANKQ++F +KD +FWL EVE LL SEDYGKDLASV NLLKKH LLEA
Sbjct: 1626 KSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQLLEA 1685
Query: 2298 DIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALN 2119
DI AH+DR+ ++N QADSL+ + F Q+ ++R I R+ +K MA RR KL+++
Sbjct: 1686 DISAHEDRLKDLNSQADSLMTSSAFDTSQVKDKRDTINGRFQKIKSMAASRRAKLNESHR 1745
Query: 2118 VHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKL 1939
+HQFFRD+DDEESWIKEKKLLV S+DYGRDL GVQNLR+KH+R++ ELA+HEP + V
Sbjct: 1746 LHQFFRDMDDEESWIKEKKLLVGSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLD 1805
Query: 1938 KGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEE 1759
G++L + + +G+++I++R+ + W +++ L R QRL+ES +Q F+ +VEEE
Sbjct: 1806 TGKKL---SDDNTIGKEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEE 1862
Query: 1758 EAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNH 1579
EAW+NEK ++ S+++G+ +A +QGLLKKH+ F+ D +HK RV D+ G LI NH
Sbjct: 1863 EAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNH 1922
Query: 1578 HAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSE 1399
H +I + L ++ ++E A R AKL +NSA+LQF WK DVVESWI EKE ++++
Sbjct: 1923 HEENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTD 1982
Query: 1398 DFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVI 1219
D+GRDLSSVQ LLTKQE FDAGL AF+ EGI IT LKDQL++++H QS AIE RH +++
Sbjct: 1983 DYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHVQSKAIEARHASLM 2042
Query: 1218 QRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNS 1039
+RW LLA+S AR+ ++E+L+L FAKKAS FNSWFENAEEDLTDPVRCNS
Sbjct: 2043 KRWSQLLANSAARKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNS 2102
Query: 1038 LEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNL 859
LEEI+ALR+AH F+ SLSSA+ DF QL +LDR+IKSF V NPYTWFTM+ALE+TWRNL
Sbjct: 2103 LEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFTMEALEETWRNL 2162
Query: 858 QRIIKEREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQE------MMEAGGTLE 697
Q+IIKERE EL +E +RQEENDKLR+EFA+ ANAFH W+ TR M+E GTLE
Sbjct: 2163 QKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRTYLLDGSCMVEESGTLE 2222
Query: 696 EQLDAVERKAKEIKANKGQLRQIEEKGAMLERNLILDNRYTEHSTVGIAQAWDQLDQLAM 517
QL+A +RK +EI+A + QL++IE+ GA +E LILDN+YTEHSTVG+AQ WDQLDQL M
Sbjct: 2223 SQLEATKRKHQEIRAMRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQQWDQLDQLGM 2282
Query: 516 RMQHNLEQQIQARNQSGVSEEALREFSMMFKHFDKEKTGRLDHQQFKSCLRALGYDLPMV 337
RMQHNLEQQIQARN +GV+EEAL+EFSMMFKHFDK+K+GRL+HQ+FKSCLR+LGYDLPMV
Sbjct: 2283 RMQHNLEQQIQARNTTGVTEEALKEFSMMFKHFDKDKSGRLNHQEFKSCLRSLGYDLPMV 2342
Query: 336 DEGQPEPEFQRILDIVDPNRDGYVTLQEYMAFMISKETENIQSSEEIEMAFRALSKEFRP 157
+EG+P+PEF+ ILD VDPNRDG+V+LQEYMAFMIS+ETEN++SSEEIE AFRALS E +P
Sbjct: 2343 EEGEPDPEFEAILDTVDPNRDGHVSLQEYMAFMISRETENVKSSEEIESAFRALSSEGKP 2402
Query: 156 YVTAEELYANLTPEQAEFCIRRMKPYMDAISGRSIQGGLDYEQFVHALF 10
YVT EELY NLT EQA++C+ MKPY+D GR + DY +F +LF
Sbjct: 2403 YVTKEELYQNLTREQADYCVSHMKPYVDG-KGRELPTAFDYVEFTRSLF 2450
>gi|17380501|sp|P16086|SPCN_RAT Spectrin alpha chain, brain (Spectrin,
non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin
alpha chain)
gi|3462887|gb|AAC33127.1| alpha-fodrin [Rattus norvegicus]
Length = 2472
Score = 2845 bits (7374), Expect = 0.0
Identities = 1422/2469 (57%), Positives = 1814/2469 (72%), Gaps = 66/2469 (2%)
Frame = -1
Query: 7218 IRILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQ 7039
+++LETA+DI +RRQ+VL Y FK+ S +R +LE++ +FQ+F+RDA+EL WI EKLQ
Sbjct: 6 VKVLETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQ 65
Query: 7038 TAQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLE 6859
A +EN++DP+NLQ K+QKH+AFEAEVQA++ I LD+TGN MI HFASE I+ RL
Sbjct: 66 VASDENYKDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLM 125
Query: 6858 ELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVE 6679
ELH W KGIKL QA KL+ ++R+C++++ WI +KE VT+E++G DLEHVE
Sbjct: 126 ELHRQWELLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVE 185
Query: 6678 ILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAA 6499
+LQ+KF++F +L H+ R+NE+NQ A KL++E H E + I K+++VN AW RL LA
Sbjct: 186 VLQKKFEEFQTDLAAHEERVNEVNQFAAKLIQEQHPEEELIKTKQEEVNAAWQRLKGLAL 245
Query: 6498 TRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLA 6319
R+ LFGA +VQRFNRD DET+ WI EK+ ++SDD+GRDL +VQAL RKHEG ERDLA
Sbjct: 246 QRQGKLFGAAEVQRFNRDVDETIGWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLA 305
Query: 6318 ALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHR 6139
ALE K+ L EA +L ++HP A I K ++ W ++ A R L+ S++L R
Sbjct: 306 ALEDKVKALCAEADRLQQSHPLSANQIQVKREELITNWEQIRTLAAERHARLDDSYRLQR 365
Query: 6138 FLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQ 5959
FLAD+RDL SW+ +MKA+I ADELA DVAGAEALL+ HQEHKGEIDA DSF +GQ
Sbjct: 366 FLADFRDLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQ 425
Query: 5958 KLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNK 5779
L+ G S EV+EKL L E+++LL LWE RR YEQCMDLQLFYRDTEQ + WM+K
Sbjct: 426 ALLAAGHYASDEVREKLSILSEERAALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSK 485
Query: 5778 QEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVA 5599
QEAFL N DLGDSLDSVE L+KKHEDFEKSL+AQEEKI ALDEFATKLIQ HYA +DVA
Sbjct: 486 QEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMEDVA 545
Query: 5598 EXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPT 5419
R L +S+ Q F RD DE+ SW+ EK+ TA D++Y DP+
Sbjct: 546 TRRDALLSRRNALHERAMHRRAQLADSFHLQQFFRDSDELKSWVNEKMKTATDEAYKDPS 605
Query: 5418 NIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVD 5239
N++GK+QKH FE EL AN++R+D + G+++ID H+A + + R+ +V +LW +L++
Sbjct: 606 NLQGKVQKHQAFEAELSANQSRIDALEKAGQKLIDVNHYAKEEVAARMNEVISLWKKLLE 665
Query: 5238 ATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIES 5059
AT KG KLREA +QQFNRN+ED+E WL E+EG +AS+DYGKDL +VQNLQKK L+E+
Sbjct: 666 ATELKGVKLREANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTNVQNLQKKHALLEA 725
Query: 5058 DFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQ 4879
D AH DR+DGI A+QFQ+ HF+A I +KQE L RY AL++P+ RK+KL +S +
Sbjct: 726 DVAAHQDRIDGITIQARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKLADSLR 785
Query: 4878 GNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSS 4699
QLFRD+EDE WIREKE +A STNRG+DLIGVQNL+KK QAL AEIA H+ +I++V+
Sbjct: 786 LQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQ 845
Query: 4698 AANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAW 4519
N M+++GHF A +++ KL++L W LK+KA +RR DL+DSLQA QY +DANEA++W
Sbjct: 846 KGNAMVEEGHFAAEDVKAKLSELNQKWEALKAKASQRRQDLEDSLQAQQYFADANEAESW 905
Query: 4518 MSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQPM-G 4342
M EKEPIVGSTDYGKDEDSAEALLKKH AL+SDL A+ +I+ LR+QA C+ Q PM
Sbjct: 906 MREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPMDD 965
Query: 4341 QLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIE 4162
+ G++ VLALYDYQEKSPREV+MKKGD+LTLLN++N+DWWKVEVNDRQGFVPAAYVK+++
Sbjct: 966 ETGKELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVKKLD 1025
Query: 4161 PGTA----------------------QQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKR 4048
P + Q ++ S+ + ++E+ YQ L+ LGE RK
Sbjct: 1026 PAQSASRENLLEEQGSIALRQGQIDNQTRITKEAGSVSLRMKQVEELYQSLLELGEKRKG 1085
Query: 4047 KLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEV 3868
LE++CK + L REAN+L +WI +EA +E+G DLEQVEVLQKKFDDF+ DLKANE
Sbjct: 1086 MLEKSCKKFMLFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANES 1145
Query: 3867 RLQEMNQIATALTSVGQTETAVRIRQQ--------------------------------- 3787
RL+++N++A L S G V+ QQ
Sbjct: 1146 RLKDINKVAEDLESEGLMAEEVQAVQQQEVYGMMPRDEADSKTASPWKSARLMVHTVATF 1205
Query: 3786 --IEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDL 3613
I++LN RWR+L LGSAHEVQRFHRD DET++WI+EK+ AL+++++G DL
Sbjct: 1206 NSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDL 1265
Query: 3612 RSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLT 3433
SVQALQRKHEG ERDLAALGDK+ SL E A RL QSHPE+AE + + ELN+ W L
Sbjct: 1266 ASVQALQRKHEGFERDLAALGDKVNSLGETAQRLIQSHPESAEDLKEKCTELNQAWTSLG 1325
Query: 3432 SKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYR 3253
+A+ RK KL DS+D QRFLSD+RDLM WI + LVSS ELA DVTGAEALLERHQE+R
Sbjct: 1326 KRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHR 1385
Query: 3252 TEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCL 3073
TEID+RA TFQAF+QFG QLL HYA+ +I+ +L +++ R LE AWV RR +LD CL
Sbjct: 1386 TEIDARAGTFQAFEQFGQQLLAHGHYASPEIKEKLDILDQERTDLEKAWVQRRMMLDHCL 1445
Query: 3072 ELQLFYRDCEQADTWMSAREAFLAQED--PSGDNVESLIKKHEDFDKAINTQEEKIKGLK 2899
ELQLF+RDCEQA+ WM+AREAFL ED S D+VE+LIKKHEDFDKAIN QEEKI L+
Sbjct: 1446 ELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQ 1505
Query: 2898 LFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIEN 2719
FA+ LI +HY + +R+++LDRW LK +I+KR KLGESQTLQQFSRD DEIE
Sbjct: 1506 AFADQLIAVDHYAKGDIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEA 1565
Query: 2718 WMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGG 2539
W++EK Q A +E+Y+DPTNIQ KHQK QAFEAELHAN+DRI +I GN+LIE C G
Sbjct: 1566 WISEKLQTASDESYKDPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGS 1625
Query: 2538 EAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSED 2359
E AV ARL AL DQW LV+ + EKS +LKEANKQ++F +KD +FWL EVE LL SED
Sbjct: 1626 EDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASED 1685
Query: 2358 YGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADR 2179
YGKDLASV NLLKKH LLEADI AH+DR+ ++N QADSL+ + F Q+ E+R I R
Sbjct: 1686 YGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKEKRDTINGR 1745
Query: 2178 YDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRK 1999
+ +K MAT RR KLS++ +HQFFRD+DDEESWIKEKKLLVSS+DYGRDL GVQNLR+K
Sbjct: 1746 FQKIKSMATSRRAKLSESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKK 1805
Query: 1998 HRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNR 1819
H+R++ ELA+HEP + V G++L + + +G+++I++R+ + W +++ L R
Sbjct: 1806 HKRLEAELAAHEPAIQGVLDTGKKL---SDDNTIGQEEIQQRLAQFVEHWKELKQLAAAR 1862
Query: 1818 HQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELH 1639
QRL+ES +Q F+ +VEEEEAW+NEK ++ S+++G+ +A +QGLLKKH+ F+ D +H
Sbjct: 1863 GQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVH 1922
Query: 1638 KQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFM 1459
K RV D+ G LI NHH +I + L ++ ++E A R AKL +NSA+LQF
Sbjct: 1923 KDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFN 1982
Query: 1458 WKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQ 1279
WK DVVESWI EKE ++++D+GRDLSSVQ LLTKQE FDAGL AF+ EGI IT LKDQ
Sbjct: 1983 WKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQ 2042
Query: 1278 LVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKAST 1099
L++++H QS AIE RH ++++RW LLA+S R+ ++E+L+L FAKKAS
Sbjct: 2043 LLAAKHIQSKAIEARHASLMKRWTQLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASA 2102
Query: 1098 FNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNV 919
FNSWFENAEEDLTDPVRCNSLEEI+ALR+AH F+ SLSSA+ DF QL +LDR+IKSF V
Sbjct: 2103 FNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRV 2162
Query: 918 GPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLANAFHAWLT 739
NPYTWFTM+ALE+TWRNLQ+IIKERE EL +E +RQEENDKLR+EFA+ ANAFH W+
Sbjct: 2163 ASNPYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQ 2222
Query: 738 NTRQE------MMEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERNLILDNRY 577
TR M+E GTLE QL+A +RK +EI+A + QL++IE+ GA +E LILDN+Y
Sbjct: 2223 ETRTYLLDGSCMVEESGTLESQLEATKRKHQEIRAMRSQLKKIEDLGAAMEEALILDNKY 2282
Query: 576 TEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMMFKHFDKEKTGR 397
TEHSTVG+AQ WDQLDQL MRMQHNLEQQIQARN +GV+EEAL+EFSMMFKHFDK+K+GR
Sbjct: 2283 TEHSTVGLAQQWDQLDQLGMRMQHNLEQQIQARNTTGVTEEALKEFSMMFKHFDKDKSGR 2342
Query: 396 LDHQQFKSCLRALGYDLPMVDEGQPEPEFQRILDIVDPNRDGYVTLQEYMAFMISKETEN 217
L+HQ+FKSCLR+LGYDLPMV+EG+P+PEF+ ILD VDPNRDG+V+LQEYMAFMIS+ETEN
Sbjct: 2343 LNHQEFKSCLRSLGYDLPMVEEGEPDPEFEAILDTVDPNRDGHVSLQEYMAFMISRETEN 2402
Query: 216 IQSSEEIEMAFRALSKEFRPYVTAEELYANLTPEQAEFCIRRMKPYMDAISGRSIQGGLD 37
++SSEEIE AFRALS E +PYVT EELY NLT EQA++C+ MKPY+D GR + D
Sbjct: 2403 VKSSEEIESAFRALSSEGKPYVTKEELYQNLTREQADYCVSHMKPYVDG-KGRELPTAFD 2461
Query: 36 YEQFVHALF 10
Y +F +LF
Sbjct: 2462 YVEFTRSLF 2470
>gi|31543764|ref|NP_741984.2| alpha-spectrin 2; alpha-fodrin;
noerythroid alpha-spectrin 2; inhibitory protein factor;
nonerythroid alpha-spectrin 2; a--fodrin; brain
alpha-spectrin [Rattus norvegicus]
gi|1495198|emb|CAA62350.1| alphaII spectrin [Rattus norvegicus]
Length = 2472
Score = 2838 bits (7358), Expect = 0.0
Identities = 1418/2469 (57%), Positives = 1812/2469 (72%), Gaps = 66/2469 (2%)
Frame = -1
Query: 7218 IRILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQ 7039
+++LETA+DI +RRQ+VL Y FK+ S +R +LE++ +FQ+F+RDA+EL WI EKLQ
Sbjct: 6 VKVLETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQ 65
Query: 7038 TAQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLE 6859
A +EN++DP+NLQ K+QKH+AFEAEVQA++ I LD+TGN MI HFASE I+ RL
Sbjct: 66 VASDENYKDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLM 125
Query: 6858 ELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVE 6679
ELH W KGIKL QA KL+ ++R+C++++ WI +KE VT+E++G DLEHVE
Sbjct: 126 ELHRQWELLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVE 185
Query: 6678 ILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAA 6499
+LQ+KF++F +L H+ R+NE+NQ A KL++E H E + I K+++VN AW RL LA
Sbjct: 186 VLQKKFEEFQTDLAAHEERVNEVNQFAAKLIQEQHPEEELIKTKQEEVNAAWQRLKGLAL 245
Query: 6498 TRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLA 6319
R+ LFGA +VQRFNRD DET+ WI EK+ ++SDD+GRDL +VQAL RKHEG ERDLA
Sbjct: 246 QRQGKLFGAAEVQRFNRDVDETIGWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLA 305
Query: 6318 ALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHR 6139
ALE K+ L EA +L ++HP A I K ++ W ++ A R L+ S++L R
Sbjct: 306 ALEDKVKALCAEADRLQQSHPLSANQIQVKREELITNWEQIRTLAAERHARLDDSYRLQR 365
Query: 6138 FLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQ 5959
FLAD+RDL SW+ +MKA+I ADELA DVAGAEALL+ HQEHKGEIDA DSF +GQ
Sbjct: 366 FLADFRDLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQ 425
Query: 5958 KLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNK 5779
L+ G S EV+EKL L E+++LL LWE RR YEQCMDLQLFYRDTEQ + WM+K
Sbjct: 426 ALLAAGHYASDEVREKLSILSEERAALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSK 485
Query: 5778 QEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVA 5599
QEAFL N DLGDSLDSVE L+KKHEDFEKSL+AQEEKI ALDEFATKLIQ HYA +DVA
Sbjct: 486 QEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMEDVA 545
Query: 5598 EXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPT 5419
R L +S+ Q F RD DE+ SW+ EK+ TA D++Y DP+
Sbjct: 546 TRRDALLSRRNALHERAMHRRAQLADSFHLQQFFRDSDELKSWVNEKMKTATDEAYKDPS 605
Query: 5418 NIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVD 5239
N++GK+QKH FE EL AN++R+D + G+++ID H+A + + R+ +V +LW +L++
Sbjct: 606 NLQGKVQKHQAFEAELSANQSRIDALEKAGQKLIDVNHYAKEEVAARMNEVISLWKKLLE 665
Query: 5238 ATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIES 5059
AT KG KLREA +QQFNRN+ED+E WL E+EG +AS+DYGKDL +VQNLQKK L+E+
Sbjct: 666 ATELKGVKLREANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTNVQNLQKKHALLEA 725
Query: 5058 DFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQ 4879
D AH DR+DGI A+QFQ+ HF+A I +KQE L RY AL++P+ RK+KL +S +
Sbjct: 726 DVAAHQDRIDGITIQARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKLADSLR 785
Query: 4878 GNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSS 4699
QLFRD+EDE WIREKE +A STNRG+DLIGVQNL+KK QAL AEIA H+ +I++V+
Sbjct: 786 LQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQ 845
Query: 4698 AANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAW 4519
N M+++GHF A +++ KL++L W LK+KA +RR DL+DSLQA QY +DANEA++W
Sbjct: 846 KGNAMVEEGHFAAEDVKAKLSELNQKWEALKAKASQRRQDLEDSLQAQQYFADANEAESW 905
Query: 4518 MSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQPM-G 4342
M EKEPIVGSTDYGKDEDSAEALLKKH AL+SDL A+ +I+ LR+QA C+ Q PM
Sbjct: 906 MREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPMDD 965
Query: 4341 QLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIE 4162
+ G++ VLALYDYQEKSPREV+MKKGD+LTLLN++N+DWWKVEVNDRQGFVPAAYVK+++
Sbjct: 966 ETGKELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVKKLD 1025
Query: 4161 PGTA----------------------QQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKR 4048
P + Q ++ S+ + ++E+ YQ L+ LGE RK
Sbjct: 1026 PAQSASRENLLEEQGSIALRQGQIDNQTRITKEAGSVSLRMKQVEELYQSLLELGEKRKG 1085
Query: 4047 KLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEV 3868
LE++CK + L REAN+L +WI +EA +E+G DLEQVEVLQKKFDDF+ DLKANE
Sbjct: 1086 MLEKSCKKFMLFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANES 1145
Query: 3867 RLQEMNQIATALTSVGQTETAVRIRQQ--------------------------------- 3787
RL+++N++A L S G V+ QQ
Sbjct: 1146 RLKDINKVAEDLESEGLMAEEVQAVQQQEVYGMMPRDEADSKTASPWKSARLMVHTVATF 1205
Query: 3786 --IEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDL 3613
I++LN RWR+L LGSAHEVQRFHRD DET++WI+EK+ AL+++++G DL
Sbjct: 1206 NSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDL 1265
Query: 3612 RSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLT 3433
SVQALQRKHEG ERDLAALGDK+ SL E A RL QSHPE+AE + + ELN+ W L
Sbjct: 1266 ASVQALQRKHEGFERDLAALGDKVNSLGETAQRLIQSHPESAEDLKEKCTELNQAWTSLG 1325
Query: 3432 SKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYR 3253
+A+ RK KL DS+D QRFLSD+RDLM WI + LVSS ELA DVTGAEALLERHQE+R
Sbjct: 1326 KRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHR 1385
Query: 3252 TEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCL 3073
TEID+RA TFQAF+QFG QLL HYA+ +I+ +L +++ R LE AWV RR +LD CL
Sbjct: 1386 TEIDARAGTFQAFEQFGQQLLAHGHYASPEIKEKLDILDQERTDLEKAWVQRRMMLDHCL 1445
Query: 3072 ELQLFYRDCEQADTWMSAREAFLAQED--PSGDNVESLIKKHEDFDKAINTQEEKIKGLK 2899
ELQLF+RDCEQA+ WM+AREAFL ED S D+VE+LIKKHEDFDKAIN QEEKI L+
Sbjct: 1446 ELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQ 1505
Query: 2898 LFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIEN 2719
FA+ LI +HY + +R+++LDRW LK +I+KR KLGESQTLQQFSRD DEIE
Sbjct: 1506 AFADQLIALDHYAKGDIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEA 1565
Query: 2718 WMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGG 2539
W++EK Q A +E+Y+DPTNIQ KHQK QAFEAELHAN+DRI +I GN+LIE C G
Sbjct: 1566 WISEKLQTASDESYKDPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGS 1625
Query: 2538 EAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSED 2359
E AV ARL AL DQW LV+ + EKS +LKEANKQ++F +KD +FWL EVE LL SED
Sbjct: 1626 EDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASED 1685
Query: 2358 YGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADR 2179
YGKDLASV NLLKKH LLEADI AH+DR+ ++N QADSL+ + F Q+ E+R I R
Sbjct: 1686 YGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKEKRDTINGR 1745
Query: 2178 YDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRK 1999
+ +K MAT RR KLS++ +HQFFRD+DDEESWIKEKKLLVSS+DYGRDL GVQNLR+K
Sbjct: 1746 FQKIKSMATSRRAKLSESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKK 1805
Query: 1998 HRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNR 1819
H+R++ ELA+HEP + V G++L + + +G+++I++R+ + W +++ L R
Sbjct: 1806 HKRLEAELAAHEPAIQGVLDTGKKL---SDDNTIGQEEIQQRLAQFVEHWKELKQLAAAR 1862
Query: 1818 HQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELH 1639
QRL+ES +Q F+ +VEEEEAW+NEK ++ S+++G+ +A +QGLLKKH+ F+ D +H
Sbjct: 1863 GQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVH 1922
Query: 1638 KQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFM 1459
K RV D+ G LI NHH +I + L ++ ++E A R A + +NSA+LQF
Sbjct: 1923 KDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKVSDLEKAAAQRKANVDENSAFLQFN 1982
Query: 1458 WKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQ 1279
WK DVVESWI EKE ++++D+GRDLSSVQ LLTKQE FDAGL AF+ EGI IT LKDQ
Sbjct: 1983 WKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQ 2042
Query: 1278 LVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKAST 1099
L++++H QS AIE RH ++++RW LLA+S R+ ++E+L+L FAKKAS
Sbjct: 2043 LLAAKHIQSKAIEARHASLMKRWTQLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASA 2102
Query: 1098 FNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNV 919
FNSWFENAEEDLTDPVRCNSLEEI+ALR+AH F+ SLSSA+ DF QL +LDR+IKSF V
Sbjct: 2103 FNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRV 2162
Query: 918 GPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLANAFHAWLT 739
NPYTWFTM+ALE+TWRNLQ+IIKERE EL +E +RQEEND +R+EFA+ ANAFH W+
Sbjct: 2163 ASNPYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDNVRQEFAQHANAFHQWIQ 2222
Query: 738 NTRQE------MMEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERNLILDNRY 577
TR M+E GTLE QL+A +RK +EI+A + QL++IE+ GA +E LILDN+Y
Sbjct: 2223 ETRTYLLDGSCMVEESGTLESQLEATKRKHQEIRAMRSQLKKIEDLGAAMEEALILDNKY 2282
Query: 576 TEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMMFKHFDKEKTGR 397
TEHSTVG+AQ WDQLDQL MRMQHNLEQQIQARN +GV+EEAL+EFSMMFKHFDK+K+GR
Sbjct: 2283 TEHSTVGLAQQWDQLDQLGMRMQHNLEQQIQARNTTGVTEEALKEFSMMFKHFDKDKSGR 2342
Query: 396 LDHQQFKSCLRALGYDLPMVDEGQPEPEFQRILDIVDPNRDGYVTLQEYMAFMISKETEN 217
L+HQ+FKSCLR+LGYDLPMV+EG+P+PEF+ ILD VDPNRDG+V+LQEYMAFMIS+ETEN
Sbjct: 2343 LNHQEFKSCLRSLGYDLPMVEEGEPDPEFEAILDTVDPNRDGHVSLQEYMAFMISRETEN 2402
Query: 216 IQSSEEIEMAFRALSKEFRPYVTAEELYANLTPEQAEFCIRRMKPYMDAISGRSIQGGLD 37
++SSEEIE AFRALS E +PYVT EELY NLT EQA++C+ MKPY+D GR + D
Sbjct: 2403 VKSSEEIESAFRALSSEGKPYVTKEELYQNLTREQADYCVSHMKPYVDG-KGRELPTAFD 2461
Query: 36 YEQFVHALF 10
Y +F +LF
Sbjct: 2462 YVEFTRSLF 2470
>gi|50757376|ref|XP_415495.1| PREDICTED: similar to spectrin alpha
chain, brain - chicken [Gallus gallus]
Length = 2498
Score = 2836 bits (7351), Expect = 0.0
Identities = 1429/2495 (57%), Positives = 1821/2495 (72%), Gaps = 92/2495 (3%)
Frame = -1
Query: 7218 IRILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQ 7039
+++LETA+DI +RRQ+VL Y FK+ S +R +LE++ +FQ+F+RDADEL WI EKLQ
Sbjct: 6 VKVLETAEDIQERRQQVLDRYHRFKELSSLRRQKLEDSYRFQFFQRDADELEKWIQEKLQ 65
Query: 7038 TAQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLE 6859
A +EN++DPSNLQ K+QKH+AFEAEVQA++ I LD+TGN MI HFASE I+ RL+
Sbjct: 66 IASDENYKDPSNLQGKLQKHQAFEAEVQANSGAIVKLDETGNQMINEGHFASETIRTRLQ 125
Query: 6858 ELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVE 6679
ELH LW KG+KL QA KL+ F+R+C++++ WI +KE VT+E++G DLEHVE
Sbjct: 126 ELHRLWELLLEKMREKGVKLLQAQKLVQFLRECEDVMDWINDKEAIVTSEELGQDLEHVE 185
Query: 6678 ILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAA 6499
+LQ+KF++F +L H+ R+NE+NQ A KL++E H E + I K+D+VN +W RL LA
Sbjct: 186 VLQKKFEEFQTDLAAHEERVNEVNQFAGKLIQEQHPEEELIKSKQDEVNASWQRLKGLAQ 245
Query: 6498 TRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLA 6319
R+ LFGA +VQRFNRD DET++WI EK ++SDD+GRDL +VQAL RKHEG ERDLA
Sbjct: 246 QRQGKLFGAAEVQRFNRDVDETISWIKEKGQLMASDDFGRDLASVQALLRKHEGLERDLA 305
Query: 6318 ALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHR 6139
ALE K+ L EA +L ++HP A I K ++ A W ++ A R L S++L R
Sbjct: 306 ALEDKVKALCAEADRLQQSHPINASQIQVKREELIANWEQIRTLAAERHARLNDSYRLQR 365
Query: 6138 FLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQ 5959
FLAD+RDL SW+ +MKA+I ADELA DVAGAEALL+ HQEHKGEIDA DSF +GQ
Sbjct: 366 FLADFRDLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDAHEDSFRSADESGQ 425
Query: 5958 KLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNK 5779
L+ G S EV+EKL L E+S+LL LWE RR YEQCMDLQLFYRDTEQ + WM+K
Sbjct: 426 ALLAAGHYASDEVKEKLTILSDERSALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSK 485
Query: 5778 QEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVA 5599
QEAFL N DLGDSLDSVE L+KKHEDFEKSL+AQEEKI ALDE K+IQ HYA DDVA
Sbjct: 486 QEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDELLNKMIQNNHYAMDDVA 545
Query: 5598 EXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPT 5419
R L +S+ Q F RD DE+ SW+ EK+ TA D++Y DP+
Sbjct: 546 TRRDALLSRRNALHERAMKRRAQLADSFHLQQFFRDSDELKSWVNEKMKTATDEAYKDPS 605
Query: 5418 NIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVD 5239
N++GK+QKH FE EL AN++R+D + G+++ID H+A+D + R+ +V +LW +L++
Sbjct: 606 NLQGKVQKHQAFEAELSANQSRIDALEKAGQKLIDVNHYASDEVAARMNEVISLWKKLLE 665
Query: 5238 ATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIES 5059
AT KG KLREA +QQFNRN+ED+E WL E+EG +AS+DYGKDL SVQNLQKK L+E+
Sbjct: 666 ATELKGIKLREANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTSVQNLQKKHALLEA 725
Query: 5058 DFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQ 4879
D AH DR+DGI A+QFQ+ HF+A I +KQE L RY AL+DP+ RK+KL +S +
Sbjct: 726 DVAAHQDRIDGITIQARQFQDAGHFDADNIKKKQEALVARYEALKDPMVARKQKLADSLR 785
Query: 4878 GNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSS 4699
QLFRDIEDE WIREKE +A STNRG+DLIGVQNL+KK QAL AEIA H+ +I++V+
Sbjct: 786 LQQLFRDIEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQ 845
Query: 4698 AANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAW 4519
N M+++GHF A +++ KL +L W LK+KA +RR DL+DSLQA QY +DANEA++W
Sbjct: 846 KGNAMVEEGHFAAEDVKIKLNELNQKWDSLKAKASQRRQDLEDSLQAQQYFADANEAESW 905
Query: 4518 MSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQPM-G 4342
M EKEPIVGSTDYGKDEDSAEALLKKH AL+SDL A+ +I+ LR+QA C+ Q P
Sbjct: 906 MREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPTDD 965
Query: 4341 QLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIE 4162
+ G++ VLALYDYQEKSPREV+MKKGD+LTLLN++N+DWWKVEVNDRQGFVPAAYVK+++
Sbjct: 966 ETGKELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVKKLD 1025
Query: 4161 PGTA----------------------QQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKR 4048
P + Q ++V S+ + ++E+ Y L+ LGE RK
Sbjct: 1026 PAQSASRENLLEEQGSIALRQEQIDNQTLITKEVGSVSLRMKQVEELYHSLLELGEKRKG 1085
Query: 4047 KLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEV 3868
LE++CK + L REAN+L +WI +EA +E+G DLEQVEVLQKKFDDF+ DLKANE
Sbjct: 1086 MLEKSCKKFMLFREANELQQWINEKEAALTNEEVGADLEQVEVLQKKFDDFQKDLKANES 1145
Query: 3867 RLQEMNQIATALTSVG-----------------------QTETA------------VRIR 3793
RL+++N++A L S G ++TA V
Sbjct: 1146 RLKDINKVANDLESEGLMAEEVQAVEHQEVYGMMPRDETDSKTASPWKSARMMVHTVATF 1205
Query: 3792 QQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDL 3613
I++LN RWR+L LGSAHEVQRFHRD DET++WI+EK+ AL+++++G DL
Sbjct: 1206 NSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDL 1265
Query: 3612 RSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLT 3433
SVQALQRKHEG ERDLAALGDK+ SL E A RL QSHPE+AE + + ELN+ W+ L
Sbjct: 1266 ASVQALQRKHEGFERDLAALGDKVNSLGETAQRLIQSHPESAEDLQEKCTELNQAWSSLG 1325
Query: 3432 SKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYR 3253
+A+ RKEKL DS+D QRFLSD+RDLM WI + LVSS ELA DVTGAEALLERHQE+R
Sbjct: 1326 KRADQRKEKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHR 1385
Query: 3252 TEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCL 3073
TEID+RA TFQAF+QFG QLL HYA+ +I+ +L +++ R LE AWV RR +LDQCL
Sbjct: 1386 TEIDARAGTFQAFEQFGQQLLARGHYASPEIKEKLDILDQERTDLEKAWVQRRMMLDQCL 1445
Query: 3072 ELQLFYRDCEQADTWMSAREAFLAQED--PSGDNVESLIKKHEDFDKAINTQEEKIKGLK 2899
ELQLF+RDCEQA+ WM+AREAFL ED S D+VE+LIKKHEDFDKAIN QEEKI L+
Sbjct: 1446 ELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAVLQ 1505
Query: 2898 LFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIEN 2719
FA+ LI +HY + +R+++LDRW LK +I+KR KLGESQTLQQFSRD DEIE
Sbjct: 1506 SFADQLIAADHYAKGVIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEA 1565
Query: 2718 WMTEKFQIAQEENYRDPTNIQ-----QKHQKQQAFEAELHANSDRIAAIIQAGNNLIENA 2554
W++EK Q A +E+Y+DPTNIQ KHQK QAFEAELHAN+DRI +I+ GN+LIE
Sbjct: 1566 WISEKLQTASDESYKDPTNIQLSKLLSKHQKHQAFEAELHANADRIRGVIEMGNSLIERG 1625
Query: 2553 KCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEIL 2374
C G E AV ARL AL DQW+ LV+ ++EKS +LKEANKQ++F +KD +FWL EVE L
Sbjct: 1626 ACAGSEDAVKARLAALADQWEFLVQKSSEKSQKLKEANKQQNFNTGIKDFDFWLSEVEAL 1685
Query: 2373 LQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRK 2194
L SEDYGKDLASV NLLKKH LLEADI AH+DR+ ++N QADSL+ + F Q+ ++R+
Sbjct: 1686 LASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKDKRE 1745
Query: 2193 LIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQ 2014
I R+ +K MA RR KL+++ +HQFFRD+DDEESWIKEKKLLVSS+DYGRDL GVQ
Sbjct: 1746 TINGRFQRIKSMAAARRAKLNESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQ 1805
Query: 2013 NLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRD 1834
NLR+KH+R++ ELA+HEP + V G++L + + +G+++I++R+ W +++
Sbjct: 1806 NLRKKHKRLEAELAAHEPAIQGVLDTGKKL---SDDNTIGKEEIQQRLAQFVDHWKELKQ 1862
Query: 1833 LTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQV 1654
L R QRL+ES +Q F+ +VEEEEAW+NEK ++ S+++G+ +A +QGLLKKH+ F+
Sbjct: 1863 LAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFET 1922
Query: 1653 DLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSA 1474
D +HK RV D+ G+ LI NHH +I + L+ ++ ++E A R AKL +NSA
Sbjct: 1923 DFTVHKDRVNDVCANGEDLIKKNNHHVENITAKMKGLKGKVSDLEKAAAQRKAKLDENSA 1982
Query: 1473 YLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRIT 1294
+LQF WK DVVESWI EKE ++++D+GRDLSSVQ LLTKQE FDAGL AF+ EGI IT
Sbjct: 1983 FLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANIT 2042
Query: 1293 ELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFA 1114
LKDQL++++H QS AIE RH ++++RW LLA+S AR+ ++E+L+L FA
Sbjct: 2043 ALKDQLLAAKHIQSKAIEVRHASLMKRWNQLLANSAARKKKLLEAQEHFRKVEDLFLTFA 2102
Query: 1113 KKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRI 934
KKAS FNSWFENAEEDLTDPVRCNSLEEI+ALR+AH F+ SLSSA+ DF QL +LDR+I
Sbjct: 2103 KKASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQI 2162
Query: 933 KSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLANAF 754
KSF V NPYTWFTM+ALE+TWRNLQ+IIKERE EL +E +RQEENDKLR+EFA+ ANAF
Sbjct: 2163 KSFRVASNPYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAF 2222
Query: 753 HAWLTNTRQE---------------------------MMEAGGTLEEQLDAVERKAKEIK 655
H W+ TR M+E GTLE QL+A +RK +EI+
Sbjct: 2223 HQWIQETRTYLLDGIAYRRVIRVYQYEVGDDLSGRSCMVEESGTLESQLEATKRKHQEIR 2282
Query: 654 ANKGQLRQIEEKGAMLERNLILDNRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARN 475
A + QL++IE+ GA +E LILDN+YTEHSTVG+AQ WDQLDQL MRMQHNLEQQIQARN
Sbjct: 2283 AMRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQQWDQLDQLGMRMQHNLEQQIQARN 2342
Query: 474 QSGVSEEALREFSMMFKHFDKEKTGRLDHQQFKSCLRALGYDLPMVDEGQPEPEFQRILD 295
+GV+EEAL+EFSMMFKHFDK+K+GRL+HQ+FKSCLR+LGYDLPMV+EG+P+PEF+ ILD
Sbjct: 2343 TTGVTEEALKEFSMMFKHFDKDKSGRLNHQEFKSCLRSLGYDLPMVEEGEPDPEFESILD 2402
Query: 294 IVDPNRDGYVTLQEYMAFMISKETENIQSSEEIEMAFRALSKEFRPYVTAEELYANLTPE 115
VDPNRDG+V+LQEYMAFMIS+ETEN++SSEEIE AFRALS E +PYVT EELY NLT E
Sbjct: 2403 TVDPNRDGHVSLQEYMAFMISRETENVKSSEEIESAFRALSSEGKPYVTKEELYQNLTRE 2462
Query: 114 QAEFCIRRMKPYMDAISGRSIQGGLDYEQFVHALF 10
QA++CI MKPYMD GR + DY +F +LF
Sbjct: 2463 QADYCISHMKPYMDG-KGRELPSAYDYIEFTRSLF 2496
>gi|134800|sp|P07751|SPCN_CHICK Spectrin alpha chain, brain (Spectrin,
non-erythroid alpha chain) (Fodrin alpha chain)
gi|71567|pir||SJCHA spectrin alpha chain, brain - chicken
Length = 2477
Score = 2832 bits (7342), Expect = 0.0
Identities = 1427/2474 (57%), Positives = 1814/2474 (72%), Gaps = 71/2474 (2%)
Frame = -1
Query: 7218 IRILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQ 7039
+++LETA+DI +RRQ+VL Y FK+ S +R +LE++ +FQ+F+RDADEL WI EKLQ
Sbjct: 6 VKVLETAEDIQERRQQVLDRYHRFKELSSLRRQKLEDSYRFQFFQRDADELGKWIQEKLQ 65
Query: 7038 TAQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLE 6859
A +EN++DPSNLQ K+QKH+AFEAEVQA++ I LD+TGN MI HFASE I+ RL+
Sbjct: 66 IASDENYKDPSNLQGKLQKHQAFEAEVQANSGAIVKLDETGNQMINEGHFASETIRTRLQ 125
Query: 6858 ELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVE 6679
ELH LW KG+KL QA KL+ F+R+C++++ WI +KE VT+E++G DLEHVE
Sbjct: 126 ELHRLWELLLEKMREKGVKLLQAQKLVQFLRECEDVMDWINDKEAIVTSEELGQDLEHVE 185
Query: 6678 ILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAA 6499
+LQ+KF++F +L H+ R+NE+NQ A KL++E H E + I K+D+VN +W RL LA
Sbjct: 186 VLQKKFEEFQTDLAAHEERVNEVNQFAGKLIQEQHPEEELIKSKQDEVNASWQRLKGLAQ 245
Query: 6498 TRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLA 6319
R+ LFGA +VQRFNRD DET++WI EK ++SDD+GRDL +VQAL RKHEG ERDLA
Sbjct: 246 QRQGKLFGAAEVQRFNRDVDETISWIKEKGQLMASDDFGRDLASVQALLRKHEGLERDLA 305
Query: 6318 ALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHR 6139
A K+ L EA +L ++HP A I K ++ A W ++ A R L S++L R
Sbjct: 306 AFHHKVKALCAEADRLQQSHPINASQIQVKREELIANWEQIRTLAAERHARLNDSYRLQR 365
Query: 6138 FLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQ 5959
FLAD+RDL SW+ +MKA+I ADELA DVAGAEALL+ HQEHKGEIDA DSF +GQ
Sbjct: 366 FLADFRDLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDAHEDSFRSADESGQ 425
Query: 5958 KLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNK 5779
L+ G S EV+EKL L E+S+LL LWE RR YEQCMDLQLFYRDTEQ + WM+K
Sbjct: 426 ALLAAGHYASDEVKEKLTILSDERSALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSK 485
Query: 5778 QEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVA 5599
QEAFL N DLGDSLDSVE L+KKHEDFEKSL+AQEEKI ALDEFATKLIQ HYA DDVA
Sbjct: 486 QEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMDDVA 545
Query: 5598 EXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPT 5419
R L +S+ Q F RD DE+ SW+ EK+ TA D++Y DP+
Sbjct: 546 TRRDALLSRRNALHERAMKRRAQLADSFHLQQFFRDSDELKSWVNEKMKTATDEAYKDPS 605
Query: 5418 NIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVD 5239
N++GK+QKH FE EL AN++R+D + G+++ID H+A+D + R+ +V +LW +L++
Sbjct: 606 NLQGKVQKHQAFEAELSANQSRIDALEKAGQKLIDVNHYASDEVAARMNEVISLWKKLLE 665
Query: 5238 ATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIES 5059
AT KG KLREA +QQFNRN+ED+E WL E+EG +AS+DYGKDL SVQNLQKK L+E+
Sbjct: 666 ATELKGIKLREANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTSVQNLQKKHALLEA 725
Query: 5058 DFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQ 4879
D AH D +DGI A+QFQ+ HF+A I +KQE L RY AL+DP+ RK+KL +S +
Sbjct: 726 DVAAHQDPIDGITIQARQFQDAGHFDADNIKKKQEALVARYEALKDPMVARKQKLADSLR 785
Query: 4878 GNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSS 4699
QLFRDIEDE WIREKE +A STNRG+DLIGVQNL+KK QAL AEIA H+ +I++V+
Sbjct: 786 LQQLFRDIEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQ 845
Query: 4698 AANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAW 4519
N M+++GHF A +++ KL +L W LK+KA +RR DL+DSLQA QY +DANEA +W
Sbjct: 846 KGNAMVEEGHFAAEDVKIKLNELNQKWDSLKAKASQRRQDLEDSLQAQQYFADANEAQSW 905
Query: 4518 MSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQPM-G 4342
M EKEPIVGSTDYGKDEDSAEALLKKH AL+SDL A+ +I+ LR+QA C+ Q P
Sbjct: 906 MREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPTDD 965
Query: 4341 QLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIE 4162
+ G++ VLALYDYQEKSPREV+MKKGD+LTLLN++N+DWWKVEVNDRQGFVPAAYVK+++
Sbjct: 966 ETGKELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVKKLD 1025
Query: 4161 PGTA----------------------QQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKR 4048
P + Q ++V S+ + ++E+ Y L+ LGE RK
Sbjct: 1026 PAQSASRENLLEEQGSIALRQEQIDNQTLITKEVGSVSLRMKQVEELYHSLLELGEKRKG 1085
Query: 4047 KLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEV 3868
LE++CK + L REAN+L +WI +EA +E+G DLEQVEVLQKKFDDF+ DLKANE
Sbjct: 1086 MLEKSCKKFMLFREANELQQWINEKEAALTNEEVGADLEQVEVLQKKFDDFQKDLKANES 1145
Query: 3867 RLQEMNQIATALTSVG-------------------QTET----------------AVRIR 3793
RL+++N++A L S G + ET V
Sbjct: 1146 RLKDINKVANDLESEGLMAEEVQAVEHQEVYGMMPRDETDSKTVSPWKSARMMVHTVATF 1205
Query: 3792 QQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDL 3613
I++LN RWR+L LGSA EVQRFHRD DET++WI+EK+ AL+++++G DL
Sbjct: 1206 NSIKELNERWRSLQQLAEERSQLLGSADEVQRFHRDADETKEWIEEKNQALNTDNYGHDL 1265
Query: 3612 RSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLT 3433
SVQALQR EG ERDLAALGDK+ SL E A RL QSHPE AE + + ELN+ W+ L
Sbjct: 1266 ASVQALQRNDEGFERDLAALGDKVNSLGETAQRLIQSHPELAEDLQEKCTELNQAWSSLG 1325
Query: 3432 SKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYR 3253
+A+ RKEKL DS+D QRFLSD+RDLM WI + LVSS ELA DVTGAEALLERHQE+R
Sbjct: 1326 KRADQRKEKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHR 1385
Query: 3252 TEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCL 3073
TEID+RA TFQAF+QFG QLL HYA+ +I+ +L +++ R LE AWV RR +LDQCL
Sbjct: 1386 TEIDARAGTFQAFEQFGQQLLARGHYASPEIKEKLDILDQERTDLEKAWVQRRMMLDQCL 1445
Query: 3072 ELQLFYRDCEQADTWMSAREAFLAQED--PSGDNVESLIKKHEDFDKAINTQEEKIKGLK 2899
ELQLF+RDCEQA+ WM+AREAFL ED S D+VE+LIKKHEDFDKAIN QEEKI L+
Sbjct: 1446 ELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAVLQ 1505
Query: 2898 LFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIEN 2719
FA+ LI +HY + +R+++LDRW LK +I+KR KLGESQTLQQFSRD DEIE
Sbjct: 1506 SFADQLIAADHYAKGVIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEA 1565
Query: 2718 WMTEKFQIAQEENYRDPTNIQ-----QKHQKQQAFEAELHANSDRIAAIIQAGNNLIENA 2554
W++EK Q A +E+Y+DPTNIQ KHQK QAFEAELHAN+DRI +I+ GN LIE
Sbjct: 1566 WISEKLQTASDESYKDPTNIQLSKLLSKHQKHQAFEAELHANADRIRGVIEMGNPLIERG 1625
Query: 2553 KCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEIL 2374
C G E AV ARL AL DQW+ LV+ ++EKS +LKEANKQ++F +KD +FWL EVE L
Sbjct: 1626 ACAGSEDAVKARLAALADQWEFLVQKSSEKSQKLKEANKQQNFNTGIKDFDFWLSEVEAL 1685
Query: 2373 LQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRK 2194
L SEDYGKDLASV NLLKKH LLEADI AH+DR+ ++N QADSL+ + F Q+ ++R+
Sbjct: 1686 LASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKDKRE 1745
Query: 2193 LIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQ 2014
I R+ +K MA RR KL+++ +HQFFRD+DDEESWIKEKKLLVSS+DYGRDL GVQ
Sbjct: 1746 TINGRFQRIKSMAAARRAKLNESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQ 1805
Query: 2013 NLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRD 1834
NLR+KH+R++ ELA+HEP + V G++L + + +G+++I++R+ W +++
Sbjct: 1806 NLRKKHKRLEAELAAHEPAIQGVLDTGKKL---SDDNTIGKEEIQQRLAQFVDHWKELKQ 1862
Query: 1833 LTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQV 1654
L R QRL+ES +Q F+ +VEEEEAW+NEK ++ S+++G+ +A +QGLLKKH+ F+
Sbjct: 1863 LAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFET 1922
Query: 1653 DLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSA 1474
D +HK RV D+ G+ LI NHH +I + L+ ++ ++E A R AKL +NSA
Sbjct: 1923 DFTVHKDRVNDVCANGEDLIKKNNHHVENITAKMKGLKGKVSDLEKAAAQRKAKLDENSA 1982
Query: 1473 YLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRIT 1294
+LQF WK DVVESWI EKE ++++D+GRDLSSVQ LLTKQE FDAGL AF+ EGI IT
Sbjct: 1983 FLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANIT 2042
Query: 1293 ELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFA 1114
LKDQL++++H QS AIE RH ++++RW LLA+S AR+ ++E+L+L FA
Sbjct: 2043 ALKDQLLAAKHIQSKAIEVRHASLMKRWNQLLANSAARKKKLLEAQEHFRKVEDLFLTFA 2102
Query: 1113 KKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRI 934
KKAS FNSWFENAEEDLTDPVRCNSLEEI+ALR+AH F+ SLSSA+ DF QL +LDR+I
Sbjct: 2103 KKASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQI 2162
Query: 933 KSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLANAF 754
KSF V NPYTWFTM+ALE+TWRNLQ+IIKERE EL +E +RQEENDKLR+EFA+ ANAF
Sbjct: 2163 KSFRVASNPYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAF 2222
Query: 753 HAWLTNTRQE------MMEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERNLI 592
H W+ TR M+E GTLE QL+A +RK +EI+A + QL++IE+ GA +E LI
Sbjct: 2223 HQWIQETRTYLLDGSCMVEESGTLESQLEATKRKHQEIRAMRSQLKKIEDLGAAMEEALI 2282
Query: 591 LDNRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMMFKHFDK 412
LDN+YTEHSTVG+AQ WDQLDQL MRMQHNLEQQIQARN +GV+EEAL+EFSMMFKHFDK
Sbjct: 2283 LDNKYTEHSTVGLAQQWDQLDQLGMRMQHNLEQQIQARNTTGVTEEALKEFSMMFKHFDK 2342
Query: 411 EKTGRLDHQQFKSCLRALGYDLPMVDEGQPEPEFQRILDIVDPNRDGYVTLQEYMAFMIS 232
+K+GRL+HQ+FKSCLR+LGYDLPMV+EG+P+PEF+ ILD VDPNRDG+V+LQEYMAFMIS
Sbjct: 2343 DKSGRLNHQEFKSCLRSLGYDLPMVEEGEPDPEFESILDTVDPNRDGHVSLQEYMAFMIS 2402
Query: 231 KETENIQSSEEIEMAFRALSKEFRPYVTAEELYANLTPEQAEFCIRRMKPYMDAISGRSI 52
+ETEN++SSEEIE AFRALS E +PYVT EELY NLT EQA++CI MKPYMD GR +
Sbjct: 2403 RETENVKSSEEIESAFRALSSERKPYVTKEELYQNLTREQADYCISHMKPYMDG-KGREL 2461
Query: 51 QGGLDYEQFVHALF 10
DY +F +LF
Sbjct: 2462 PSAYDYIEFTRSLF 2475
>gi|1805280|gb|AAB41498.1| alpha II spectrin [Homo sapiens]
Length = 2477
Score = 2830 bits (7335), Expect = 0.0
Identities = 1417/2474 (57%), Positives = 1811/2474 (72%), Gaps = 71/2474 (2%)
Frame = -1
Query: 7218 IRILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQ 7039
+++LETA+DI +RRQ+VL Y FK+ S +R +LE++ +FQ+F+RDA+EL WI EKLQ
Sbjct: 6 VKVLETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQ 65
Query: 7038 TAQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLE 6859
A +EN++DP+NLQ K+QKH+AFEAEVQA++ I LD+TGN MI HFASE I+ RL
Sbjct: 66 IASDENYKDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLM 125
Query: 6858 ELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVE 6679
ELH W KGIKL QA KL+ ++R+C++++ WI +KE VT+E++G DLEHVE
Sbjct: 126 ELHRQWELLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVE 185
Query: 6678 ILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAA 6499
+LQ+KF++F ++ H+ R+NE+NQ A KL++E H E + I K+D+VN AW RL LA
Sbjct: 186 VLQKKFEEFQTDMAAHEERVNEVNQFAAKLIQEQHPEEELIKTKQDEVNAAWQRLKGLAL 245
Query: 6498 TRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLA 6319
R+ LFGA +VQRFNRD DET++WI EK+ ++SDD+GRDL +VQAL RKHEG ERDLA
Sbjct: 246 QRQGKLFGAAEVQRFNRDVDETISWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLA 305
Query: 6318 ALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHR 6139
ALE K+ L EA +L ++HP A I K ++ W ++ A R L S++L R
Sbjct: 306 ALEDKVKALCAEADRLQQSHPLSATQIQVKREELITNWEQIRTLAAERHARLNDSYRLQR 365
Query: 6138 FLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQ 5959
FLAD+RDL SW+ +MKA+I ADELA DVAGAEALL+ HQEHKGEIDA DSF +GQ
Sbjct: 366 FLADFRDLTSWVTEMKALINADELASDVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQ 425
Query: 5958 KLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNK 5779
L+ G S EV+EKL L E+++LL LWE RR YEQCMDLQLFYRDTEQ + WM+K
Sbjct: 426 ALLAAGHYASDEVREKLTVLSEERAALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSK 485
Query: 5778 QEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVA 5599
QEAFL N DLGDSLDSVE L+KKHEDFEKSL+AQEEKI ALDEFATKLIQ HYA +DVA
Sbjct: 486 QEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMEDVA 545
Query: 5598 EXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPT 5419
R L +S+ Q F RD DE+ SW+ EK+ TA D++Y DP+
Sbjct: 546 TRRDALLSRRNALHERAMRRRAQLADSFHLQQFFRDSDELKSWVNEKMKTATDEAYKDPS 605
Query: 5418 NIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVD 5239
N++GK+QKH FE EL AN++R+D + G+++ID H+A D + R+ +V +LW +L++
Sbjct: 606 NLQGKVQKHQAFEAELSANQSRIDALEKAGQKLIDVNHYAKDEVAARMNEVISLWKKLLE 665
Query: 5238 ATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIES 5059
AT KG KLREA +QQFNRN+ED+E WL E+EG +AS+DYGKDL +VQNLQKK L+E+
Sbjct: 666 ATELKGIKLREANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTNVQNLQKKHALLEA 725
Query: 5058 DFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQ 4879
D AH DR+DGI A+QFQ+ HF+A I +KQE L RY AL++P+ RK+KL +S +
Sbjct: 726 DVAAHQDRIDGITIQARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKLADSLR 785
Query: 4878 GNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSS 4699
QLFRD+EDE WIREKE +A STNRG+DLIGVQNL+KK QAL AEIA H+ +I++V+
Sbjct: 786 LQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQ 845
Query: 4698 AANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAW 4519
N M+++GHF A +++ KL +L W LK+KA +RR DL+DSLQA QY +DANEA++W
Sbjct: 846 KGNAMVEEGHFAAEDVKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADANEAESW 905
Query: 4518 MSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQPMG- 4342
M EKEPIVGSTDYGKDEDSAEALLKKH AL+SDL A+ +I+ LR+QA C+ Q P
Sbjct: 906 MREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPTDD 965
Query: 4341 QLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIE 4162
+ G++ VLALYDYQEKSPREV+MKKGD+LTLLN++N+DWWKVEVNDRQGFVPAAYVK+++
Sbjct: 966 ETGKELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVKKLD 1025
Query: 4161 PGTA----------------------QQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKR 4048
P + Q ++ S+ + ++E+ Y L+ LGE RK
Sbjct: 1026 PAQSASRENLLEEQGSIALRQEQIDNQTRITKEAGSVSLRMKQVEELYHSLLELGEKRKG 1085
Query: 4047 KLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEV 3868
LE++CK + L REAN+L +WI +EA +E+G DLEQVEVLQKKFDDF+ DLKANE
Sbjct: 1086 MLEKSCKKFMLFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANES 1145
Query: 3867 RLQEMNQIATALTSVGQTETAVRIRQQ--------------------------------- 3787
RL+++N++A L S G V+ QQ
Sbjct: 1146 RLKDINKVAEDLESEGLMAEEVQAVQQQEVYGMMPRDETDSKTASPWKSARLMVHTVATF 1205
Query: 3786 --IEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDL 3613
I++LN RWR+L LGSAHEVQRFHRD DET++WI+EK+ AL+++++G DL
Sbjct: 1206 NSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDL 1265
Query: 3612 RSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLT 3433
SVQALQRKHEG ERDLAALGDK+ SL E A RL QSHPE+AE + + ELN+ W+ L
Sbjct: 1266 ASVQALQRKHEGFERDLAALGDKVNSLGETAERLIQSHPESAEDLQEKCTELNQAWSSLG 1325
Query: 3432 SKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYR 3253
+A+ RK KL DS+D QRFLSD+RDLM WI + LVSS ELA DVTGAEALLERHQE+R
Sbjct: 1326 KRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHR 1385
Query: 3252 TEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCL 3073
TEID+RA TFQAF+QFG QLL HYA+ +I+ +L +++ R LE AWV RR +LDQCL
Sbjct: 1386 TEIDARAGTFQAFEQFGQQLLAHGHYASPEIKQKLDILDQERADLEKAWVQRRMMLDQCL 1445
Query: 3072 ELQLFYRDCEQADTWMSAREAFLAQEDP--SGDNVESLIKKHEDFDKAINTQEEKIKGLK 2899
ELQLF+RDCEQA+ WM+AREAFL ED S D+VE+LIKKHEDFDKAIN QEEKI L+
Sbjct: 1446 ELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQ 1505
Query: 2898 LFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIEN 2719
FA+ LI HY ++ +R+++LDRW LK +I+KR KLGESQTLQQFSRD DEIE
Sbjct: 1506 AFADQLIAAGHYAKGDISSRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEA 1565
Query: 2718 WMTEKFQIAQEENYRDPTNIQ-----QKHQKQQAFEAELHANSDRIAAIIQAGNNLIENA 2554
W++EK Q A +E+Y+DPTNIQ KHQK QAFEAELHAN+DRI +I GN+LIE
Sbjct: 1566 WISEKLQTASDESYKDPTNIQLSKLLSKHQKHQAFEAELHANADRIRGVIDMGNSLIERG 1625
Query: 2553 KCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEIL 2374
C G E AV ARL AL DQW LV+ + EKS +LKEANKQ++F +KD +FWL EVE L
Sbjct: 1626 ACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEAL 1685
Query: 2373 LQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRK 2194
L SEDYGKDLASV NLLKKH LLEADI AH+DR+ ++N QADSL+ + F Q+ ++R
Sbjct: 1686 LASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKDKRD 1745
Query: 2193 LIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQ 2014
I R+ +K MA RR KL+++ +HQFFRD+DDEESWIKEKKLLV S+DYGRDL GVQ
Sbjct: 1746 TINGRFQKIKSMAASRRAKLNESHRLHQFFRDMDDEESWIKEKKLLVGSEDYGRDLTGVQ 1805
Query: 2013 NLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRD 1834
NLR+KH+R++ ELA+HEP + V G++L + + +G+++I++R+ + W +++
Sbjct: 1806 NLRKKHKRLEAELAAHEPAIQGVLDTGKKL---SDDNTIGKEEIQQRLAQFVEHWKELKQ 1862
Query: 1833 LTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQV 1654
L R QRL+ES +Q F+ +VEEEEAW+NEK ++ S+++G+ +A +QGLLKKH+ F+
Sbjct: 1863 LAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFET 1922
Query: 1653 DLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSA 1474
D +HK RV D+ G LI NHH +I + L ++ ++E A R A + +NSA
Sbjct: 1923 DFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKVSDLEKAAAQRKANVDENSA 1982
Query: 1473 YLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRIT 1294
+LQF WK DVVESWI EKE ++++D+GRDLSSVQ LLTKQE FDAGL AF+ EGI IT
Sbjct: 1983 FLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANIT 2042
Query: 1293 ELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFA 1114
LKDQL++++H QS AIE RH ++++RW LLA+S AR+ ++E+L+L FA
Sbjct: 2043 ALKDQLLAAKHVQSKAIEARHASLMKRWSQLLANSAARKKKLLEAQSHFRKVEDLFLTFA 2102
Query: 1113 KKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRI 934
KKAS FNSWFENAEEDLTDPVRCNSLEEI+ALR+AH F+ SLSSA+ DF QL +LDR+I
Sbjct: 2103 KKASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQI 2162
Query: 933 KSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLANAF 754
KSF V NPYTWFTM+ALE+TWRNLQ+IIKERE EL +E +RQEENDKLR+EFA+ ANAF
Sbjct: 2163 KSFRVASNPYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAF 2222
Query: 753 HAWLTNTRQE------MMEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERNLI 592
H W+ TR M+E GTLE QL+A +RK +EI+A + QL++IE+ GA +E LI
Sbjct: 2223 HQWIQETRTYLLDGSCMVEESGTLESQLEATKRKHQEIRAMRSQLKKIEDLGAAMEEALI 2282
Query: 591 LDNRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMMFKHFDK 412
LDN+YTEHSTVG+AQ WDQLDQL MRMQHNLEQQIQARN +GV+EEAL+EFSMMFKHFDK
Sbjct: 2283 LDNKYTEHSTVGLAQQWDQLDQLGMRMQHNLEQQIQARNTTGVTEEALKEFSMMFKHFDK 2342
Query: 411 EKTGRLDHQQFKSCLRALGYDLPMVDEGQPEPEFQRILDIVDPNRDGYVTLQEYMAFMIS 232
+K+GRL+HQ+FKSCLR+LGYDLPMV+EG+P+PEF+ ILD VDPNRDG+V+LQEYMAFMIS
Sbjct: 2343 DKSGRLNHQEFKSCLRSLGYDLPMVEEGEPDPEFEAILDTVDPNRDGHVSLQEYMAFMIS 2402
Query: 231 KETENIQSSEEIEMAFRALSKEFRPYVTAEELYANLTPEQAEFCIRRMKPYMDAISGRSI 52
+ETEN++SSEEIE AFRALS E +PYVT EELY NLT EQA++C+ MKPY+D GR +
Sbjct: 2403 RETENVKSSEEIESAFRALSSEGKPYVTKEELYQNLTREQADYCVSHMKPYVDG-KGREL 2461
Query: 51 QGGLDYEQFVHALF 10
DY +F +LF
Sbjct: 2462 PTAFDYVEFTRSLF 2475
>gi|4507191|ref|NP_003118.1| spectrin, alpha, non-erythrocytic 1
(alpha-fodrin) [Homo sapiens]
gi|2493433|sp|Q13813|SPCN_HUMAN Spectrin alpha chain, brain
(Spectrin, non-erythroid alpha chain) (Alpha-II spectrin)
(Fodrin alpha chain)
gi|106032|pir||A35715 fodrin alpha chain - human
gi|179106|gb|AAA51790.1| nonerythroid alpha-spectrin
Length = 2472
Score = 2821 bits (7313), Expect = 0.0
Identities = 1411/2469 (57%), Positives = 1805/2469 (72%), Gaps = 66/2469 (2%)
Frame = -1
Query: 7218 IRILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQ 7039
+++LETA+DI +RRQ+VL Y FK+ S +R +LE++ +FQ+F+RDA+EL WI EKLQ
Sbjct: 6 VKVLETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQ 65
Query: 7038 TAQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLE 6859
A +EN++DP+NLQ K+QKH+AFEAEVQA++ I LD+TGN MI HFASE I+ RL
Sbjct: 66 IASDENYKDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLM 125
Query: 6858 ELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVE 6679
ELH W KGIKL QA L+ ++R+C++++ WI +KE VT+E++G DLEHVE
Sbjct: 126 ELHRQWELLLEKMREKGIKLLQAQNLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVE 185
Query: 6678 ILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAA 6499
+LQ+KF++F ++ H+ R+NE+NQ A KL++E H E + I K+D+VN AW RL LA
Sbjct: 186 VLQKKFEEFQTDMAAHEERVNEVNQFAAKLIQEQHPEEELIKTKQDEVNAAWQRLKGLAL 245
Query: 6498 TRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLA 6319
R+ LFGA +VQRFNRD DET++WI EK+ ++SDD+GRDL +VQAL RKHEG ERDLA
Sbjct: 246 QRQGKLFGAAEVQRFNRDVDETISWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLA 305
Query: 6318 ALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHR 6139
ALE K+ L EA +L ++HP A I K ++ W ++ A R L S++L R
Sbjct: 306 ALEDKVKALCAEADRLQQSHPLSATQIQVKREELITNWEQIRTLAAERHARLNDSYRLQR 365
Query: 6138 FLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQ 5959
FLAD+RDL SW+ +MKA+I ADELA DVAGAEALL+ HQEHKGEIDA DSF +GQ
Sbjct: 366 FLADFRDLTSWVTEMKALINADELASDVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQ 425
Query: 5958 KLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNK 5779
L+ G S EV+EKL L E+++LL LWE RR YEQCMDLQLFYRDTEQ + WM+K
Sbjct: 426 ALLAAGHYASDEVREKLTVLSEERAALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSK 485
Query: 5778 QEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVA 5599
QEAFL N DLGD LDSVE L+KKHEDFEKSL+AQEEKI ALDEFATKLIQ HYA +DVA
Sbjct: 486 QEAFLLNEDLGDFLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMEDVA 545
Query: 5598 EXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPT 5419
R L +S+ Q F RD DE+ SW+ EK+ TA D++Y DP+
Sbjct: 546 TRRDALLSRRNALHERAMRRRAQLADSFHLQQFFRDSDELKSWVNEKMKTATDEAYKDPS 605
Query: 5418 NIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVD 5239
N++GK+QKH FE EL AN++R+D + G+++ID H+A D + R+ +V +LW +L++
Sbjct: 606 NLQGKVQKHQAFEAELSANQSRIDALEKAGQKLIDVNHYAKDEVAARMNEVISLWKKLLE 665
Query: 5238 ATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIES 5059
AT KG KLREA +QQFNRN+ED+E WL E+EG +AS+DYGKDL +VQNLQKK L+E+
Sbjct: 666 ATELKGIKLREANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTNVQNLQKKHALLEA 725
Query: 5058 DFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQ 4879
D AH DR+DG+ A+QFQ+ HF+A I +KQE L RY AL++P+ RK+KL +S +
Sbjct: 726 DVAAHQDRIDGVTIQARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKLADSLR 785
Query: 4878 GNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSS 4699
QLFRD+EDE WIREKE +A STNRG+DLIGVQNL+KK QAL AEIA H+ +I++V+
Sbjct: 786 LQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQ 845
Query: 4698 AANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAW 4519
N M+++GHF A +++ KL +L W LK+KA +RR DL+DSLQA QY +DANEA++W
Sbjct: 846 KGNAMVEEGHFAAEDVKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADANEAESW 905
Query: 4518 MSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQPMG- 4342
M EKEPIVGSTDYGKDEDSAEALLKKH AL+SDL A+ +I+ LR+QA C+ Q P
Sbjct: 906 MREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPTDD 965
Query: 4341 QLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIE 4162
+ G++ VLALYDYQEKSPREV+MKKGD+LTLLN++N+DWWKVEVNDRQGFVPAAYVK+++
Sbjct: 966 ETGKELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVKKLD 1025
Query: 4161 PGTA----------------------QQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKR 4048
P + Q ++ S+ + ++E+ Y L+ LGE RK
Sbjct: 1026 PAQSASRENLLEEQGSIALRQEQIDNQTRITKEAGSVSLRMKQVEELYHSLLELGEKRKG 1085
Query: 4047 KLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEV 3868
LE++CK + L REAN+L +WI +EA +E+G DLEQVEVLQKKFDDF+ DLKANE
Sbjct: 1086 MLEKSCKKFMLFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANES 1145
Query: 3867 RLQEMNQIATALTSVGQTETAVRIRQQ--------------------------------- 3787
RL+++N++A L S G V+ QQ
Sbjct: 1146 RLKDINKVAEDLESEGLMAEEVQAVQQQEVYGMMPRDETDSKTASPWKSARLMVHTVATF 1205
Query: 3786 --IEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDL 3613
I++LN RWR+L LGSAHEVQRFHRD DET++WI+EK+ AL+++++G DL
Sbjct: 1206 NSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDL 1265
Query: 3612 RSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLT 3433
SVQALQRKHEG ERDLAALGDK+ SL E A RL QSHPE+AE + + ELN+ W+ L
Sbjct: 1266 ASVQALQRKHEGFERDLAALGDKVNSLGETAERLTQSHPESAEDLQEKCTELNQAWSSLG 1325
Query: 3432 SKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYR 3253
+A+ RK KL DS+D QRFLSD+RDLM WI + LVSS ELA DVTGAEALLERHQE+R
Sbjct: 1326 KRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHR 1385
Query: 3252 TEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCL 3073
TEID+RA TFQAF+QFG QLL HYA+ +I+ +L +++ R LE AWV RR +LDQCL
Sbjct: 1386 TEIDARAGTFQAFEQFGQQLLAHGHYASPEIKQKLDILDQERADLEKAWVQRRMMLDQCL 1445
Query: 3072 ELQLFYRDCEQADTWMSAREAFLAQEDP--SGDNVESLIKKHEDFDKAINTQEEKIKGLK 2899
ELQLF+RDCEQA+ WM+AREAFL ED S D+VE+LIKKHEDFDKAIN QEEKI L+
Sbjct: 1446 ELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQ 1505
Query: 2898 LFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIEN 2719
FA+ LI HY ++ +R+++LDRW LK +I+KR KLGESQTLQQFSRD DEIE
Sbjct: 1506 AFADQLIAAGHYAKGDISSRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEA 1565
Query: 2718 WMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGG 2539
W++EK Q A +E+Y+DPTNIQ KHQK QAFEAELHAN+DRI +I GN+LIE C G
Sbjct: 1566 WISEKLQTASDESYKDPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGN 1625
Query: 2538 EAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSED 2359
E AV ARL AL DQW LV+ + EKS +LKEANKQ++F +KD+ FWL EVE LL SED
Sbjct: 1626 EDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDIAFWLSEVEALLASED 1685
Query: 2358 YGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADR 2179
YGKDLASV NLLKKH LLEADI AH+DR+ ++N QADSL+ + F Q+ ++R I R
Sbjct: 1686 YGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKDKRDTINGR 1745
Query: 2178 YDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRK 1999
+ +K MA RR KL+++ +HQFFRD+DDEESWIKEKKLLV S+DYGRDL GVQNLR+K
Sbjct: 1746 FQKIKSMAASRRAKLNESHRLHQFFRDMDDEESWIKEKKLLVGSEDYGRDLTGVQNLRKK 1805
Query: 1998 HRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNR 1819
H+R++ ELA+HEP + V G++L + + +G+++I++R+ + W +++ L R
Sbjct: 1806 HKRLEAELAAHEPAIQGVLDTGKKL---SDDNTIGKEEIQQRLAQFVEHWKELKQLAAAR 1862
Query: 1818 HQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELH 1639
QRL+ES +Q F+ +VEEEEAW+NEK ++ S+++G+ +A +QGLLKKH+ F+ +H
Sbjct: 1863 GQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETAFTVH 1922
Query: 1638 KQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFM 1459
K RV D+ G LI NHH +I + L ++ ++E A R A + +NSA+LQF
Sbjct: 1923 KDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKVSDLEKAAAQRKANVDENSAFLQFN 1982
Query: 1458 WKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQ 1279
WK DVVESWI EKE ++++D+GRDLSSVQ LLTKQE FDAGL AF+ EGI IT LKDQ
Sbjct: 1983 WKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQ 2042
Query: 1278 LVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKAST 1099
L++++H QS AIE RH ++++RW LLA+S AR+ ++E+L+L FAKKAS
Sbjct: 2043 LLAAKHVQSKAIEARHASLMKRWSQLLANSAARKKKLLEAQSHFRKVEDLFLTFAKKASA 2102
Query: 1098 FNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNV 919
FNSWFENAEEDLTDPVRCNSLEEI+ALR+AH F+ SLSSA+ DF QL +LDR+IKSF V
Sbjct: 2103 FNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRV 2162
Query: 918 GPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLANAFHAWLT 739
NPYTWFTM+ALE+TWRNLQ+IIKERE EL +E +RQEENDKLR+EFA+ ANAFH W+
Sbjct: 2163 ASNPYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQ 2222
Query: 738 NTRQE------MMEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERNLILDNRY 577
TR M+E GTLE QL+A +RK +EI+A + QL++IE+ GA +E LILDN+Y
Sbjct: 2223 ETRTYLLDGSCMVEESGTLESQLEATKRKHQEIRAMRSQLKKIEDLGAAMEEALILDNKY 2282
Query: 576 TEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMMFKHFDKEKTGR 397
TEHSTVG+AQ WDQLDQL MRMQHNLEQQIQARN +GV+EEAL+EFSMMFKHFDK+K+GR
Sbjct: 2283 TEHSTVGLAQQWDQLDQLGMRMQHNLEQQIQARNTTGVTEEALKEFSMMFKHFDKDKSGR 2342
Query: 396 LDHQQFKSCLRALGYDLPMVDEGQPEPEFQRILDIVDPNRDGYVTLQEYMAFMISKETEN 217
L+HQ KSCLR+LGYDLPMV+EG+P+PEF+ ILD VDPNRDG+V+LQEYMAFMIS+ETEN
Sbjct: 2343 LNHQDGKSCLRSLGYDLPMVEEGEPDPEFEAILDTVDPNRDGHVSLQEYMAFMISRETEN 2402
Query: 216 IQSSEEIEMAFRALSKEFRPYVTAEELYANLTPEQAEFCIRRMKPYMDAISGRSIQGGLD 37
++SSEEIE AFRALS E +PYVT EELY NLT EQA++C+ MKP +D GR + D
Sbjct: 2403 VKSSEEIESAFRALSSEGKPYVTKEELYQNLTREQADYCVSHMKPIVDG-KGRELPTAFD 2461
Query: 36 YEQFVHALF 10
Y +F +LF
Sbjct: 2462 YVEFTRSLF 2470
>gi|1334744|emb|CAA32663.1| spectrin alpha chain [Gallus gallus]
Length = 2449
Score = 2806 bits (7275), Expect = 0.0
Identities = 1415/2451 (57%), Positives = 1796/2451 (72%), Gaps = 71/2451 (2%)
Frame = -1
Query: 7149 FKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENFRDPSNLQAKIQKHEAF 6970
FK+ S +R +LE++ +FQ+F+RDADEL WI EKLQ A +EN++DPSNLQ K+QKH+AF
Sbjct: 1 FKELSSLRRQKLEDSYRFQFFQRDADELGKWIQEKLQIASDENYKDPSNLQGKLQKHQAF 60
Query: 6969 EAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQA 6790
EAEVQA++ I LD+TGN MI HFASE I+ RL+ELH LW KG+KL QA
Sbjct: 61 EAEVQANSGAIVKLDETGNQMINEGHFASETIRTRLQELHRLWELLLEKMREKGVKLLQA 120
Query: 6789 LKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEI 6610
KL+ F+R+C++++ WI +KE VT+E++G DLEHVE+LQ+KF++F +L H+ R+NE+
Sbjct: 121 QKLVQFLRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQKKFEEFQTDLAAHEERVNEV 180
Query: 6609 NQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETL 6430
NQ A KL++E H E + I K+D+VN +W RL LA R+ LFGA +VQRFNRD DET+
Sbjct: 181 NQFAGKLIQEQHPEEELIKSKQDEVNASWQRLKGLAQQRQGKLFGAAEVQRFNRDVDETI 240
Query: 6429 AWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDR 6250
+WI EK ++SDD+GRDL +VQAL RKHEG ERDLAA K+ L EA +L ++HP
Sbjct: 241 SWIKEKGQLMASDDFGRDLASVQALLRKHEGLERDLAAFHHKVKALCAEADRLQQSHPIN 300
Query: 6249 AEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADE 6070
A I K ++ A W ++ A R L S++L RFLAD+RDL SW+ +MKA+I ADE
Sbjct: 301 ASQIQVKREELIANWEQIRTLAAERHARLNDSYRLQRFLADFRDLTSWVTEMKALINADE 360
Query: 6069 LAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHE 5890
LA DVAGAEALL+ HQEHKGEIDA DSF +GQ L+ G S EV+EKL L E
Sbjct: 361 LANDVAGAEALLDRHQEHKGEIDAHEDSFRSADESGQALLAAGHYASDEVKEKLTILSDE 420
Query: 5889 KSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKK 5710
+S+LL LWE RR YEQCMDLQLFYRDTEQ + WM+KQEAFL N DLGDSLDSVE L+KK
Sbjct: 421 RSALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEALLKK 480
Query: 5709 HEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNA 5530
HEDFEKSL+AQEEKI ALDEFATKLIQ HYA DDVA R
Sbjct: 481 HEDFEKSLSAQEEKITALDEFATKLIQNNHYAMDDVATRRDALLSRRNALHERAMKRRAQ 540
Query: 5529 LKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRL 5350
L +S+ Q F RD DE+ SW+ EK+ TA D++Y DP+N++GK+QKH FE EL AN++R+
Sbjct: 541 LADSFHLQQFFRDSDELKSWVNEKMKTATDEAYKDPSNLQGKVQKHQAFEAELSANQSRI 600
Query: 5349 DDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIE 5170
D + G+++ID H+A+D + R+ +V +LW +L++AT KG KLREA +QQFNRN+E
Sbjct: 601 DALEKAGQKLIDVNHYASDEVAARMNEVISLWKKLLEATELKGIKLREANQQQQFNRNVE 660
Query: 5169 DVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEE 4990
D+E WL E+EG +AS+DYGKDL SVQNLQKK L+E+D AH D +DGI A+QFQ+
Sbjct: 661 DIELWLYEVEGHLASDDYGKDLTSVQNLQKKHALLEADVAAHQDPIDGITIQARQFQDAG 720
Query: 4989 HFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAG 4810
HF+A I +KQE L RY AL+DP+ RK+KL +S + QLFRDIEDE WIREKE +A
Sbjct: 721 HFDADNIKKKQEALVARYEALKDPMVARKQKLADSLRLQQLFRDIEDEETWIREKEPIAA 780
Query: 4809 STNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQL 4630
STNRG+DLIGVQNL+KK QAL AEIA H+ +I++V+ N M+++GHF A +++ KL +L
Sbjct: 781 STNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKIKLNEL 840
Query: 4629 RDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEAL 4450
W LK+KA +RR DL+DSLQA QY +DANEA +WM EKEPIVGSTDYGKDEDSAEAL
Sbjct: 841 NQKWDSLKAKASQRRQDLEDSLQAQQYFADANEAQSWMREKEPIVGSTDYGKDEDSAEAL 900
Query: 4449 LKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQPM-GQLGRDCVLALYDYQEKSPREVSM 4273
LKKH AL+SDL A+ +I+ LR+QA C+ Q P + G++ VLALYDYQEKSPREV+M
Sbjct: 901 LKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPTDDETGKELVLALYDYQEKSPREVTM 960
Query: 4272 KKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIEPGTA------------------- 4150
KKGD+LTLLN++N+DWWKVEVNDRQGFVPAAYVK+++P +
Sbjct: 961 KKGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVKKLDPAQSASRENLLEEQGSIALRQEQ 1020
Query: 4149 ---QQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIK 3979
Q ++V S+ + ++E+ Y L+ LGE RK LE++CK + L REAN+L +WI
Sbjct: 1021 IDNQTLITKEVGSVSLRMKQVEELYHSLLELGEKRKGMLEKSCKKFMLFREANELQQWIN 1080
Query: 3978 SREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVG------- 3820
+EA +E+G DLEQVEVLQKKFDDF+ DLKANE RL+++N++A L S G
Sbjct: 1081 EKEAALTNEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVANDLESEGLMAEEVQ 1140
Query: 3819 ------------QTET----------------AVRIRQQIEDLNARWRALXXXXXXXXXQ 3724
+ ET V I++LN RWR+L
Sbjct: 1141 AVEHQEVYGMMPRDETDSKTVSPWKSARMMVHTVATFNSIKELNERWRSLQQLAEERSQL 1200
Query: 3723 LGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDK 3544
LGSA EVQRFHRD DET++WI+EK+ AL+++++G DL SVQALQR EG ERDLAALGDK
Sbjct: 1201 LGSADEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRNDEGFERDLAALGDK 1260
Query: 3543 IKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDY 3364
+ SL E A RL QSHPE AE + + ELN+ W+ L +A+ RKEKL DS+D QRFLSD+
Sbjct: 1261 VNSLGETAQRLIQSHPELAEDLQEKCTELNQAWSSLGKRADQRKEKLGDSHDLQRFLSDF 1320
Query: 3363 RDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNS 3184
RDLM WI + LVSS ELA DVTGAEALLERHQE+RTEID+RA TFQAF+QFG QLL
Sbjct: 1321 RDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAR 1380
Query: 3183 HHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFL 3004
HYA+ +I+ +L +++ R LE AWV RR +LDQCLELQLF+RDCEQA+ WM+AREAFL
Sbjct: 1381 GHYASPEIKEKLDILDQERTDLEKAWVQRRMMLDQCLELQLFHRDCEQAENWMAAREAFL 1440
Query: 3003 AQED--PSGDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQ 2830
ED S D+VE+LIKKHEDFDKAIN QEEKI L+ FA+ LI +HY + +R++
Sbjct: 1441 NTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAVLQSFADQLIAADHYAKGVIANRRNE 1500
Query: 2829 ILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNIQ-- 2656
+LDRW LK +I+KR KLGESQTLQQFSRD DEIE W++EK Q A +E+Y+DPTNIQ
Sbjct: 1501 VLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPTNIQLS 1560
Query: 2655 ---QKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLL 2485
KHQK QAFEAELHAN+DRI +I+ GN LIE C G E AV ARL AL DQW+ L
Sbjct: 1561 KLLSKHQKHQAFEAELHANADRIRGVIEMGNPLIERGACAGSEDAVKARLAALADQWEFL 1620
Query: 2484 VKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLL 2305
V+ ++EKS +LKEANKQ++F +KD +FWL EVE LL SEDYGKDLASV NLLKKH LL
Sbjct: 1621 VQKSSEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQLL 1680
Query: 2304 EADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKA 2125
EADI AH+DR+ ++N QADSL+ + F Q+ ++R+ I R+ +K MA RR KL+++
Sbjct: 1681 EADISAHEDRLKDLNSQADSLMTSSAFDTSQVKDKRETINGRFQRIKSMAAARRAKLNES 1740
Query: 2124 LNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLV 1945
+HQFFRD+DDEESWIKEKKLLVSS+DYGRDL GVQNLR+KH+R++ ELA+HEP + V
Sbjct: 1741 HRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGV 1800
Query: 1944 KLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVE 1765
G++L + + +G+++I++R+ W +++ L R QRL+ES +Q F+ +VE
Sbjct: 1801 LDTGKKL---SDDNTIGKEEIQQRLAQFVDHWKELKQLAAARGQRLEESLEYQQFVANVE 1857
Query: 1764 EEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNG 1585
EEEAW+NEK ++ S+++G+ +A +QGLLKKH+ F+ D +HK RV D+ G+ LI
Sbjct: 1858 EEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCANGEDLIKKN 1917
Query: 1584 NHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVR 1405
NHH +I + L+ ++ ++E A R AKL +NSA+LQF WK DVVESWI EKE ++
Sbjct: 1918 NHHVENITAKMKGLKGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLK 1977
Query: 1404 SEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTN 1225
++D+GRDLSSVQ LLTKQE FDAGL AF+ EGI IT LKDQL++++H QS AIE RH +
Sbjct: 1978 TDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEVRHAS 2037
Query: 1224 VIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRC 1045
+++RW LLA+S AR+ ++E+L+L FAKKAS FNSWFENAEEDLTDPVRC
Sbjct: 2038 LMKRWNQLLANSAARKKKLLEAQEHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRC 2097
Query: 1044 NSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWR 865
NSLEEI+ALR+AH F+ SLSSA+ DF QL +LDR+IKSF V NPYTWFTM+ALE+TWR
Sbjct: 2098 NSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFTMEALEETWR 2157
Query: 864 NLQRIIKEREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQE------MMEAGGT 703
NLQ+IIKERE EL +E +RQEENDKLR+EFA+ ANAFH W+ TR M+E GT
Sbjct: 2158 NLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRTYLLDGSCMVEESGT 2217
Query: 702 LEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERNLILDNRYTEHSTVGIAQAWDQLDQL 523
LE QL+A +RK +EI+A + QL++IE+ GA +E LILDN+YTEHSTVG+AQ WDQLDQL
Sbjct: 2218 LESQLEATKRKHQEIRAMRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQQWDQLDQL 2277
Query: 522 AMRMQHNLEQQIQARNQSGVSEEALREFSMMFKHFDKEKTGRLDHQQFKSCLRALGYDLP 343
MRMQHNLEQQIQARN +GV+EEAL+EFSMMFKHFDK+K+GRL+HQ+FKSCLR+LGYDLP
Sbjct: 2278 GMRMQHNLEQQIQARNTTGVTEEALKEFSMMFKHFDKDKSGRLNHQEFKSCLRSLGYDLP 2337
Query: 342 MVDEGQPEPEFQRILDIVDPNRDGYVTLQEYMAFMISKETENIQSSEEIEMAFRALSKEF 163
MV+EG+P+PEF+ ILD VDPNRDG+V+LQEYMAFMIS+ETEN++SSEEIE AFRALS E
Sbjct: 2338 MVEEGEPDPEFESILDTVDPNRDGHVSLQEYMAFMISRETENVKSSEEIESAFRALSSER 2397
Query: 162 RPYVTAEELYANLTPEQAEFCIRRMKPYMDAISGRSIQGGLDYEQFVHALF 10
+PYVT EELY NLT EQA++CI MKPYMD GR + DY +F +LF
Sbjct: 2398 KPYVTKEELYQNLTREQADYCISHMKPYMDG-KGRELPSAYDYIEFTRSLF 2447
Score = 692 bits (1787), Expect = 0.0
Identities = 512/2179 (23%), Positives = 987/2179 (44%), Gaps = 33/2179 (1%)
Frame = -1
Query: 7191 IHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENF-R 7015
I ++ EV + K +Q ++ +L A + Q F RD DE WI EK Q ++F R
Sbjct: 198 IKSKQDEVNASWQRLKGLAQQRQGKLFGAAEVQRFNRDVDETISWIKEKGQLMASDDFGR 257
Query: 7014 DPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXX 6835
D +++QA ++KHE E ++ A + L + + Q + + I+ + EEL A W
Sbjct: 258 DLASVQALLRKHEGLERDLAAFHHKVKALCAEADRLQQSHPINASQIQVKREELIANWEQ 317
Query: 6834 XXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDD 6655
+ +L + +L F+ ++ W+ E + + A+++ D+ E L + +
Sbjct: 318 IRTLAAERHARLNDSYRLQRFLADFRDLTSWVTEMKALINADELANDVAGAEALLDRHQE 377
Query: 6654 FLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFG 6475
E+ H+ +++ L+ GH D++ +K ++D L L R++
Sbjct: 378 HKGEIDAHEDSFRSADESGQALLAAGHYASDEVKEKLTILSDERSALLELWELRRQQYEQ 437
Query: 6474 AHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQ 6295
+Q F RD ++ W+ +++ L ++D G L++V+AL +KHE E+ L+A E K+
Sbjct: 438 CMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITA 497
Query: 6294 LEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDL 6115
L++ A KL + + + + + D + NAL E+A R+ L SF L +F D +L
Sbjct: 498 LDEFATKLIQNNHYAMDDVATRRDALLSRRNALHERAMKRRAQLADSFHLQQFFRDSDEL 557
Query: 6114 ISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIP 5935
SW+ + K DE KD + + ++ HQ + E+ A + AGQKL+++
Sbjct: 558 KSWVNE-KMKTATDEAYKDPSNLQGKVQKHQAFEAELSANQSRIDALEKAGQKLIDVNHY 616
Query: 5934 ESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANT 5755
S EV ++ ++ LL E + I + Q F R+ E E W+ + E LA+
Sbjct: 617 ASDEVAARMNEVISLWKKLLEATELKGIKLREANQQQQFNRNVEDIELWLYEVEGHLASD 676
Query: 5754 DLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXX 5575
D G L SV++L KKH E +AA ++ I+ + A + H+ AD++ +
Sbjct: 677 DYGKDLTSVQNLQKKHALLEADVAAHQDPIDGITIQARQFQDAGHFDADNIKKKQEALVA 736
Query: 5574 XXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSY-LDPTNIRGKLQ 5398
R L +S + Q RD ++ +WI EK A + D ++ L+
Sbjct: 737 RYEALKDPMVARKQKLADSLRLQQLFRDIEDEETWIREKEPIAASTNRGKDLIGVQNLLK 796
Query: 5397 KHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGA 5218
KH + E+ +E R+ + G +++ GHFAA+ + +L ++N W+ L +++
Sbjct: 797 KHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKIKLNELNQKWDSLKAKASQRRQ 856
Query: 5217 KLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHND 5038
L ++ QQ+ + + ++W+ E E V S DYGKD S + L KK + SD +A+
Sbjct: 857 DLEDSLQAQQYFADANEAQSWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGS 916
Query: 5037 RVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRD 4858
+ +++ AQ +++ V E ++ AL D EK R++ +
Sbjct: 917 SIQALREQAQSCRQQ------VAPTDDETGKELVLALYDYQEKSPREVTMKKGDILTLLN 970
Query: 4857 IEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAA--NDM 4684
++ W E G +KK A+ A+ ++ +E S A +
Sbjct: 971 STNKDWWKVEVNDRQGFVPAA--------YVKKLDP--AQSASRENLLEEQGSIALRQEQ 1020
Query: 4683 IQQGHFLAPEIRD---KLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMS 4513
I + E+ ++ Q+ + + L EKR+ L+ S + +ANE W++
Sbjct: 1021 IDNQTLITKEVGSVSLRMKQVEELYHSLLELGEKRKGMLEKSCKKFMLFREANELQQWIN 1080
Query: 4512 EKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQPMGQLG 4333
EKE + + + G D + E L KK DL+A + ++D+ K A+ + + G +
Sbjct: 1081 EKEAALTNEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVANDLESE----GLMA 1136
Query: 4332 RDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIEPGT 4153
+ + ++QE V ++ D + V +
Sbjct: 1137 EE--VQAVEHQE------------VYGMMPRDETD--------------SKTVSPWKSAR 1168
Query: 4152 AQQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSR 3973
H NSI E+ ++++ L L E R + L A + + R+A++ EWI+ +
Sbjct: 1169 MMVHTVATFNSI----KELNERWRSLQQLAEERSQLLGSADEVQRFHRDADETKEWIEEK 1224
Query: 3972 EAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIR 3793
G DL V+ LQ+ + F+ DL A ++ + + A L E A ++
Sbjct: 1225 NQALNTDNYGHDLASVQALQRNDEGFERDLAALGDKVNSLGETAQRLIQ-SHPELAEDLQ 1283
Query: 3792 QQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDL 3613
++ +LN W +L +LG +H++QRF D + WI + S++ +D+
Sbjct: 1284 EKCTELNQAWSSLGKRADQRKEKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDV 1343
Query: 3612 RSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLT 3433
+AL +H+ ++ A ++ ++ +L A+ +I + L+++ L
Sbjct: 1344 TGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLARGHYASPEIKEKLDILDQERTDLE 1403
Query: 3432 SKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYR 3253
R+ L + Q F D W+A+ +++++ + + EAL+++H+++
Sbjct: 1404 KAWVQRRMMLDQCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFD 1463
Query: 3252 TEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCL 3073
I+ + F +QL+ + HYA G I NR V + + L+ + +R+ L +
Sbjct: 1464 KAINVQEEKIAVLQSFADQLIAADHYAKGVIANRRNEVLDRWRRLKAQMIEKRSKLGESQ 1523
Query: 3072 ELQLFYRDCEQADTWMSAREAFLAQE---DPSGDNVESLI---KKHEDFDKAINTQEEKI 2911
LQ F RD ++ + W+S + + E DP+ + L+ +KH+ F+ ++ ++I
Sbjct: 1524 TLQQFSRDVDEIEAWISEKLQTASDESYKDPTNIQLSKLLSKHQKHQAFEAELHANADRI 1583
Query: 2910 KGLKLFAESLIKNNHY--DSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRD 2737
+G+ LI+ AV + + D+W L + +K KL E+ Q F+
Sbjct: 1584 RGVIEMGNPLIERGACAGSEDAVKARLAALADQWEFLVQKSSEKSQKLKEANKQQNFNTG 1643
Query: 2736 ADEIENWMTEKFQIAQEENY-RDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIE 2560
+ + W++E + E+Y +D ++ +K Q EA++ A+ DR+ + ++L+
Sbjct: 1644 IKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMT 1703
Query: 2559 NAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVE 2380
++ + V + + +N ++ + + +L E+++ F + D E W+ E +
Sbjct: 1704 SSAFDTSQ--VKDKRETINGRFQRIKSMAAARRAKLNESHRLHQFFRDMDDEESWIKEKK 1761
Query: 2379 ILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAER 2200
+L+ SEDYG+DL V+NL KKH LEA++ AH+ + + + L +++ ++I +R
Sbjct: 1762 LLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGKEEIQQR 1821
Query: 2199 RKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPG 2020
D + +K++A R +L ++L QF ++++EE+WI EK LV+S+DYG L
Sbjct: 1822 LAQFVDHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAA 1881
Query: 2019 VQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQI 1840
+Q L +KH +T+ H+ +V+ V GE+L++ + + I +M+ L+ +
Sbjct: 1882 IQGLLKKHEAFETDFTVHKDRVNDVCANGEDLIK---KNNHHVENITAKMKGLKGKVSDL 1938
Query: 1839 RDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTF 1660
R +LDE+ AF F + E+W+ EK+ L +D++G +++ VQ LL K +TF
Sbjct: 1939 EKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETF 1998
Query: 1659 QVDLELHKQR-VADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRD 1483
L+ +Q +A++ D L+ + + I+ R L R ++ + + R KL +
Sbjct: 1999 DAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEVRHASLMKRWNQLLANSAARKKKLLE 2058
Query: 1482 --------NSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLN 1327
+L F K SW E+ + L ++ L +AF + L+
Sbjct: 2059 AQEHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLS 2118
Query: 1326 AFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXX 1147
+ + + ++ EL Q+ S +P + + W+NL + R
Sbjct: 2119 SAQAD-FNQLAELDRQIKSFRVASNPYTWFTMEALEETWRNLQKIIKERELELQKEQRRQ 2177
Query: 1146 XQIEELYLAFAKKASTFNSWFENAEEDLTD----PVRCNSLE-EIRALRDAHGEFQRSLS 982
+ ++L FA+ A+ F+ W + L D +LE ++ A + H E +
Sbjct: 2178 EENDKLRQEFAQHANAFHQWIQETRTYLLDGSCMVEESGTLESQLEATKRKHQE----IR 2233
Query: 981 SAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQE 802
+ ++++DL ++ + N YT + L W L ++ + L ++ Q +
Sbjct: 2234 AMRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQQWDQLDQLGMRMQHNLEQQIQARN 2293
Query: 801 E---NDKLRREFAKLANAF 754
++ +EF+ + F
Sbjct: 2294 TTGVTEEALKEFSMMFKHF 2312
Score = 536 bits (1380), Expect = e-150
Identities = 453/2004 (22%), Positives = 875/2004 (43%), Gaps = 118/2004 (5%)
Frame = -1
Query: 7200 ADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILE-KLQTAQEE 7024
A I +R+E++ ++ + + + RL ++ + Q F D +L W+ E K +E
Sbjct: 301 ASQIQVKREELIANWEQIRTLAAERHARLNDSYRLQRFLADFRDLTSWVTEMKALINADE 360
Query: 7023 NFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHAL 6844
D + +A + +H+ + E+ AH + + D++G A++ H+AS+ +K++L L
Sbjct: 361 LANDVAGAEALLDRHQEHKGEIDAHEDSFRSADESGQALLAAGHYASDEVKEKLTILSDE 420
Query: 6843 WXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRK 6664
+ + +Q + L F R +++ W+ ++E ++ ED+G L+ VE L +K
Sbjct: 421 RSALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEALLKK 480
Query: 6663 FDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEG 6484
+DF K L + +I +++ A KL++ H D + +RD + + L+ A R+
Sbjct: 481 HEDFEKSLSAQEEKITALDEFATKLIQNNHYAMDDVATRRDALLSRRNALHERAMKRRAQ 540
Query: 6483 LFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGK 6304
L + +Q+F RD+DE +W+ EK + ++D+ +D +N+Q +KH+ E +L+A + +
Sbjct: 541 LADSFHLQQFFRDSDELKSWVNEK-MKTATDEAYKDPSNLQGKVQKHQAFEAELSANQSR 599
Query: 6303 MLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADY 6124
+ LEK KL + + ++ + + ++ + W L E + + L + Q +F +
Sbjct: 600 IDALEKAGQKLIDVNHYASDEVAARMNEVISLWKKLLEATELKGIKLREANQQQQFNRNV 659
Query: 6123 RDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEM 5944
D+ W+ +++ + +D+ KD+ + L + H + ++ A D + ++ +
Sbjct: 660 EDIELWLYEVEGHLASDDYGKDLTSVQNLQKKHALLEADVAAHQDPIDGITIQARQFQDA 719
Query: 5943 GIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFL 5764
G ++ +++K E L +L R+ + LQ +RD E ETW+ ++E
Sbjct: 720 GHFDADNIKKKQEALVARYEALKDPMVARKQKLADSLRLQQLFRDIEDEETWIREKEPIA 779
Query: 5763 ANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXX 5584
A+T+ G L V++L+KKH+ + +A E +I A+ + +++ H+AA+DV
Sbjct: 780 ASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKIKLNE 839
Query: 5583 XXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSY-LDPTNIRG 5407
R L++S + Q + D +E SW+ EK Y D +
Sbjct: 840 LNQKWDSLKAKASQRRQDLEDSLQAQQYFADANEAQSWMREKEPIVGSTDYGKDEDSAEA 899
Query: 5406 KLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELV--DAT 5233
L+KH +L A + + +R + D G L + E + T
Sbjct: 900 LLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPTDDETGKELVLALYDYQEKSPREVT 959
Query: 5232 NKKG--AKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIES 5059
KKG L + N+ + + D + ++ Y K L Q+ ++ L E
Sbjct: 960 MKKGDILTLLNSTNKDWWKVEVNDRQGFVPAA--------YVKKLDPAQSASRENLLEEQ 1011
Query: 5058 DFNA-HNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESH 4882
A +++D + ++ + + + +++ Y++L + EKRK L +S
Sbjct: 1012 GSIALRQEQIDNQTLITKEVGS--------VSLRMKQVEELYHSLLELGEKRKGMLEKSC 1063
Query: 4881 QGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVS 4702
+ LFR+ + WI EKE + G DL V+ L KK ++ ++S+++ ++
Sbjct: 1064 KKFMLFREANELQQWINEKEAALTNEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDIN 1123
Query: 4701 SAANDMIQQGHFLAPEIR-------------------------------------DKLAQ 4633
AND+ +G +A E++ + + +
Sbjct: 1124 KVANDLESEG-LMAEEVQAVEHQEVYGMMPRDETDSKTVSPWKSARMMVHTVATFNSIKE 1182
Query: 4632 LRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEA 4453
L + WR L+ AE+R L + + ++ DA+E W+ EK + + +YG D S +A
Sbjct: 1183 LNERWRSLQQLAEERSQLLGSADEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQA 1242
Query: 4452 LLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQPMGQ-LGRDCVLALYDYQEKSPREVS 4276
L + DL A + L + A + + + L C + R
Sbjct: 1243 LQRNDEGFERDLAALGDKVNSLGETAQRLIQSHPELAEDLQEKCTELNQAWSSLGKRADQ 1302
Query: 4275 MKK---------------GDVLTLLNA----SNRDWWKVEVNDRQGFVPAAYVKRIE--- 4162
K+ D+++ +N + D +V + + R E
Sbjct: 1303 RKEKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDA 1362
Query: 4161 -PGTAQQHAQ--QQVNSIGGKQS-EIEDKYQRL------MMLGETRKRKLEEACKGYQLL 4012
GT Q Q QQ+ + G S EI++K L + ++R + + C QL
Sbjct: 1363 RAGTFQAFEQFGQQLLARGHYASPEIKEKLDILDQERTDLEKAWVQRRMMLDQCLELQLF 1422
Query: 4011 -REANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATA 3835
R+ W+ +REA ++ G L+ VE L KK +DF + E ++ + A
Sbjct: 1423 HRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAVLQSFADQ 1482
Query: 3834 LTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQE 3655
L + V ++ E L+ RWR L +LG + +Q+F RDVDE WI E
Sbjct: 1483 LIAADHYAKGVIANRRNEVLD-RWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISE 1541
Query: 3654 KDDALDSEDFGRDLRSVQ-----ALQRKHEGVERDLAALGDKIKSLDEKANRL--RQSHP 3496
K E + +D ++Q + +KH+ E +L A D+I+ + E N L R +
Sbjct: 1542 KLQTASDESY-KDPTNIQLSKLLSKHQKHQAFEAELHANADRIRGVIEMGNPLIERGACA 1600
Query: 3495 EAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSS 3316
+ + + L +QW L K++ + +KL ++ Q F + +D W++ + L++S
Sbjct: 1601 GSEDAVKARLAALADQWEFLVQKSSEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLAS 1660
Query: 3315 QELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVN 3136
++ D+ LL++HQ +I + + + + L+ S + ++++ + +N
Sbjct: 1661 EDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKDKRETIN 1720
Query: 3135 EARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGD--NVESLI 2962
+ ++ ARR L++ L F+RD + ++W+ ++ ++ ED D V++L
Sbjct: 1721 GRFQRIKSMAAARRAKLNESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLR 1780
Query: 2961 KKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKR 2782
KKH+ + + E I+G+ + L +N + ++ Q +D W LK+ +
Sbjct: 1781 KKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGKEEIQQRLAQFVDHWKELKQLAAARG 1840
Query: 2781 FKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDP-TNIQQKHQKQQAFEAELHANS 2605
+L ES QQF + +E E W+ EK + E+Y D IQ +K +AFE + +
Sbjct: 1841 QRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHK 1900
Query: 2604 DRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSF 2425
DR+ + G +LI+ K ++A++K L + L K ++ +L E + F
Sbjct: 1901 DRVNDVCANGEDLIK--KNNHHVENITAKMKGLKGKVSDLEKAAAQRKAKLDENSAFLQF 1958
Query: 2424 MAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVA-HQDRVGEMNEQAD 2248
+E W+GE E L+++DYG+DL+SV+ LL K +A + A Q+ + + D
Sbjct: 1959 NWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKD 2018
Query: 2247 SLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDD------- 2089
LL Q + I R + R++ + + R+ KL L + FR ++D
Sbjct: 2019 QLLAAKHIQSKAIEVRHASLMKRWNQLLANSAARKKKL---LEAQEHFRKVEDLFLTFAK 2075
Query: 2088 ----EESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELL 1921
SW + + ++ L ++ LR H + L+S + + + EL
Sbjct: 2076 KASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQL----AELD 2131
Query: 1920 RSAAEAGVGEDQIK-KRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEA--- 1753
R V + ME LE++W ++ + R L + + Q + +E A
Sbjct: 2132 RQIKSFRVASNPYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHA 2191
Query: 1752 -----WMNEKQQIL--GS---DNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGD 1603
W+ E + L GS + G + ++ +KH + + +++ DL +
Sbjct: 2192 NAFHQWIQETRTYLLDGSCMVEESGTLESQLEATKRKHQEIRA-MRSQLKKIEDLGAAME 2250
Query: 1602 TLIHNGNHHAPH----IKQRCDQL 1543
+ N + H + Q+ DQL
Sbjct: 2251 EALILDNKYTEHSTVGLAQQWDQL 2274
>gi|34852958|ref|XP_346648.1| hypothetical protein XP_346647 [Rattus
norvegicus]
Length = 2362
Score = 2640 bits (6843), Expect = 0.0
Identities = 1325/2331 (56%), Positives = 1696/2331 (71%), Gaps = 66/2331 (2%)
Frame = -1
Query: 7218 IRILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQ 7039
+++LETA+DI +RRQ+VL Y FK+ S +R +LE++ +FQ+F+RDA+EL WI EKLQ
Sbjct: 6 VKVLETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQ 65
Query: 7038 TAQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLE 6859
A +EN++DP+NLQ K+QKH+AFEAEVQA++ I LD+TGN MI HFASE I+ RL
Sbjct: 66 VASDENYKDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLM 125
Query: 6858 ELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVE 6679
ELH W KGIKL QA KL+ ++R+C++++ WI +KE VT+E++G DLEHVE
Sbjct: 126 ELHRQWELLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVE 185
Query: 6678 ILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAA 6499
+LQ+KF++F +L H+ R+NE+NQ A KL++E H E + I K+++VN AW RL LA
Sbjct: 186 VLQKKFEEFQTDLAAHEERVNEVNQFAAKLIQEQHPEEELIKTKQEEVNAAWQRLKGLAL 245
Query: 6498 TRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLA 6319
R+ LFGA +VQRFNRD DET+ WI EK+ ++SDD+GRDL +VQAL RKHEG ERDLA
Sbjct: 246 QRQGKLFGAAEVQRFNRDVDETIGWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLA 305
Query: 6318 ALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHR 6139
ALE K+ L EA +L ++HP A I K ++ W ++ A R L+ S++L R
Sbjct: 306 ALEDKVKALCAEADRLQQSHPLSANQIQVKREELITNWEQIRTLAAERHARLDDSYRLQR 365
Query: 6138 FLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQ 5959
FLAD+RDL SW+ +MKA+I ADELA DVAGAEALL+ HQEHKGEIDA DSF +GQ
Sbjct: 366 FLADFRDLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQ 425
Query: 5958 KLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNK 5779
L+ G S EV+EKL L E+++LL LWE RR YEQCMDLQLFYRDTEQ + WM+K
Sbjct: 426 ALLAAGHYASDEVREKLSILSEERAALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSK 485
Query: 5778 QEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVA 5599
QEAFL N DLGDSLDSVE L+KKHEDFEKSL+AQEEKI ALDEFATKLIQ HYA +DVA
Sbjct: 486 QEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMEDVA 545
Query: 5598 EXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPT 5419
R L +S+ Q F RD DE+ SW+ EK+ TA D++Y DP+
Sbjct: 546 TRRDALLSRRNALHERAMHRRAQLADSFHLQQFFRDSDELKSWVNEKMKTATDEAYKDPS 605
Query: 5418 NIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVD 5239
N++GK+QKH FE EL AN++R+D + G+++ID H+A + + R+ +V +LW +L++
Sbjct: 606 NLQGKVQKHQAFEAELSANQSRIDALEKAGQKLIDVNHYAKEEVAARMNEVISLWKKLLE 665
Query: 5238 ATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIES 5059
AT KG KLREA +QQFNRN+ED+E WL E+EG +AS+DYGKDL +VQNLQKK L+E+
Sbjct: 666 ATELKGVKLREANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTNVQNLQKKHALLEA 725
Query: 5058 DFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQ 4879
D AH DR+DGI A+QFQ+ HF+A I +KQE L RY AL++P+ RK+KL +S +
Sbjct: 726 DVAAHQDRIDGITIQARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKLADSLR 785
Query: 4878 GNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSS 4699
QLFRD+EDE WIREKE +A STNRG+DLIGVQNL+KK QAL AEIA H+ +I++V+
Sbjct: 786 LQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQ 845
Query: 4698 AANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAW 4519
N M+++GHF A +++ KL++L W LK+KA +RR DL+DSLQA QY +DANEA++W
Sbjct: 846 KGNAMVEEGHFAAEDVKAKLSELNQKWEALKAKASQRRQDLEDSLQAQQYFADANEAESW 905
Query: 4518 MSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQPM-G 4342
M EKEPIVGSTDYGKDEDSAEALLKKH AL+SDL A+ +I+ LR+QA C+ Q PM
Sbjct: 906 MREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPMDD 965
Query: 4341 QLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIE 4162
+ G++ VLALYDYQEKSPREV+MKKGD+LTLLN++N+DWWKVEVNDRQGFVPAAYVK+++
Sbjct: 966 ETGKELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVKKLD 1025
Query: 4161 PGTA----------------------QQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKR 4048
P + Q ++ S+ + ++E+ YQ L+ LGE RK
Sbjct: 1026 PAQSASRENLLEEQGSIALRQGQIDNQTRITKEAGSVSLRMKQVEELYQSLLELGEKRKG 1085
Query: 4047 KLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEV 3868
LE++CK + L REAN+L +WI +EA +E+G DLEQVEVLQKKFDDF+ DLKANE
Sbjct: 1086 MLEKSCKKFMLFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANES 1145
Query: 3867 RLQEMNQIATALTSVGQTETAVRIRQQ--------------------------------- 3787
RL+++N++A L S G V+ QQ
Sbjct: 1146 RLKDINKVAEDLESEGLMAEEVQAVQQQEVYGMMPRDEADSKTASPWKSARLMVHTVATF 1205
Query: 3786 --IEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDL 3613
I++LN RWR+L LGSAHEVQRFHRD DET++WI+EK+ AL+++++G DL
Sbjct: 1206 NSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDL 1265
Query: 3612 RSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLT 3433
SVQALQRKHEG ERDLAALGDK+ SL E A RL QSHPE+AE + + ELN+ W L
Sbjct: 1266 ASVQALQRKHEGFERDLAALGDKVNSLGETAQRLIQSHPESAEDLKEKCTELNQAWTSLG 1325
Query: 3432 SKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYR 3253
+A+ RK KL DS+D QRFLSD+RDLM WI + LVSS ELA DVTGAEALLERHQE+R
Sbjct: 1326 KRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHR 1385
Query: 3252 TEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCL 3073
TEID+RA TFQAF+QFG QLL HYA+ +I+ +L +++ R LE AWV RR +LD CL
Sbjct: 1386 TEIDARAGTFQAFEQFGQQLLAHGHYASPEIKEKLDILDQERTDLEKAWVQRRMMLDHCL 1445
Query: 3072 ELQLFYRDCEQADTWMSAREAFLAQED--PSGDNVESLIKKHEDFDKAINTQEEKIKGLK 2899
ELQLF+RDCEQA+ WM+AREAFL ED S D+VE+LIKKHEDFDKAIN QEEKI L+
Sbjct: 1446 ELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQ 1505
Query: 2898 LFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIEN 2719
FA+ LI +HY + +R+++LDRW LK +I+KR KLGESQTLQQFSRD DEIE
Sbjct: 1506 AFADQLIAVDHYAKGDIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEA 1565
Query: 2718 WMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGG 2539
W++EK Q A +E+Y+DPTNIQ KHQK QAFEAELHAN+DRI +I GN+LIE C G
Sbjct: 1566 WISEKLQTASDESYKDPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGS 1625
Query: 2538 EAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSED 2359
E AV ARL AL DQW LV+ + EKS +LKEANKQ++F +KD +FWL EVE LL SED
Sbjct: 1626 EDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASED 1685
Query: 2358 YGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADR 2179
YGKDLASV NLLKKH LLEADI AH+DR+ ++N QADSL+ + F Q+ E+R I R
Sbjct: 1686 YGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKEKRDTINGR 1745
Query: 2178 YDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRK 1999
+ +K MAT RR KLS++ +HQFFRD+DDEESWIKEKKLLVSS+DYGRDL GVQNLR+K
Sbjct: 1746 FQKIKSMATSRRAKLSESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKK 1805
Query: 1998 HRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNR 1819
H+R++ ELA+HEP + V G++L + + +G+++I++R+ + W +++ L R
Sbjct: 1806 HKRLEAELAAHEPAIQGVLDTGKKL---SDDNTIGQEEIQQRLAQFVEHWKELKQLAAAR 1862
Query: 1818 HQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELH 1639
QRL+ES +Q F+ +VEEEEAW+NEK ++ S+++G+ +A +QGLLKKH+ F+ D +H
Sbjct: 1863 GQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVH 1922
Query: 1638 KQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFM 1459
K RV D+ G LI NHH +I + L ++ ++E A R AKL +NSA+LQF
Sbjct: 1923 KDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFN 1982
Query: 1458 WKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQ 1279
WK DVVESWI EKE ++++D+GRDLSSVQ LLTKQE FDAGL AF+ EGI IT LKDQ
Sbjct: 1983 WKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQ 2042
Query: 1278 LVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKAST 1099
L++++H QS AIE RH ++++RW LLA+S R+ ++E+L+L FAKKAS
Sbjct: 2043 LLAAKHIQSKAIEARHASLMKRWTQLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASA 2102
Query: 1098 FNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNV 919
FNSWFENAEEDLTDPVRCNSLEEI+ALR+AH F+ SLSSA+ DF QL +LDR+IKSF V
Sbjct: 2103 FNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRV 2162
Query: 918 GPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLANAFHAWLT 739
NPYTWFTM+ALE+TWRNLQ+IIKERE EL +E +RQEENDKLR+EFA+ ANAFH W+
Sbjct: 2163 ASNPYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQ 2222
Query: 738 NTRQE------MMEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERNLILDNRY 577
TR M+E GTLE QL+A +RK +EI+A + QL++IE+ GA +E LILDN+Y
Sbjct: 2223 ETRTYLLDGSCMVEESGTLESQLEATKRKHQEIRAMRSQLKKIEDLGAAMEEALILDNKY 2282
Query: 576 TEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMMFK 424
TEHSTVG+AQ WDQLDQL MRMQHNLEQQIQARN +GV+EEAL+EFSMM +
Sbjct: 2283 TEHSTVGLAQQWDQLDQLGMRMQHNLEQQIQARNTTGVTEEALKEFSMMLQ 2333
>gi|38074607|ref|XP_207079.2| spectrin alpha 2 [Mus musculus]
Length = 1818
Score = 2144 bits (5555), Expect = 0.0
Identities = 1071/1820 (58%), Positives = 1355/1820 (73%), Gaps = 64/1820 (3%)
Frame = -1
Query: 5277 LRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVS 5098
+ +V +LW +L++AT KG KLREA +QQFNRN+ED+E WL E+EG +AS+DYGKDL +
Sbjct: 1 MNEVISLWKKLLEATELKGIKLREANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTN 60
Query: 5097 VQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDP 4918
VQNLQKK L+E+D AH DR+DGI A+QFQ+ HF+A I +KQE L RY AL++P
Sbjct: 61 VQNLQKKHALLEADVAAHQDRIDGITIQARQFQDAGHFDAENIKKKQEALVARYEALKEP 120
Query: 4917 LEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAE 4738
+ RK+KL +S + QLFRD+EDE WIREKE +A STNRG+DLIGVQNL+KK QAL AE
Sbjct: 121 MVARKQKLADSLRLQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAE 180
Query: 4737 IANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQA 4558
IA H+ +I++V+ N M+++GHF A +++ KL++L W LK+KA +RR DL+DSLQA
Sbjct: 181 IAGHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLSELNQKWEALKAKASQRRQDLEDSLQA 240
Query: 4557 HQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQ 4378
QY +DANEA++WM EKEPIVGSTDYGKDEDSAEALLKKH AL+SDL A+ +I+ LR+Q
Sbjct: 241 QQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQ 300
Query: 4377 ASQCKYQEQPMG-QLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASN----RDWWKVE 4213
A C+ Q PM + G++ VLALYDYQEKSPREV+MKKGD+LTLLN++N RDWWKVE
Sbjct: 301 AQSCRQQVAPMDDETGKELVLALYDYQEKSPREVTMKKGDILTLLNSTNKARHRDWWKVE 360
Query: 4212 VNDRQGFVPAAYVKRIEPGTA----------------------QQHAQQQVNSIGGKQSE 4099
VNDRQGFVPAAYVK+++P + Q ++ S+ + +
Sbjct: 361 VNDRQGFVPAAYVKKLDPAQSASRENLLEEQGSIALRQGQIDNQTRITKEAGSVSLRMKQ 420
Query: 4098 IEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEV 3919
+E+ YQ L+ LGE RK LE++CK + L REAN+L +WI +EA +E+G DLEQVEV
Sbjct: 421 VEELYQSLLELGEKRKGMLEKSCKKFMLFREANELQQWITEKEAALTNEEVGADLEQVEV 480
Query: 3918 LQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQ---------------- 3787
LQKKFDDF+ DLKANE RL+++N++A L S G V+ QQ
Sbjct: 481 LQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYGAMPRDEADSKT 540
Query: 3786 -------------------IEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDW 3664
I++LN RWR+L LGSAHEVQRFHRD DET++W
Sbjct: 541 ASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEW 600
Query: 3663 IQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAE 3484
I+EK+ AL+++++G DL SVQALQRKHEG ERDLAALGDK+ SL E A RL QSHPE+AE
Sbjct: 601 IEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAQRLIQSHPESAE 660
Query: 3483 QIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELA 3304
+ + ELN+ W L +A+ RK KL DS+D QRFLSD+RDLM WI + LVSS ELA
Sbjct: 661 DLKEKCTELNQAWTSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELA 720
Query: 3303 NDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARK 3124
DVTGAEALLERHQE+RTEID+RA TFQAF+QFG QLL HYA+ +I+ +L +++ R
Sbjct: 721 KDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKEKLDILDQERT 780
Query: 3123 GLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDP--SGDNVESLIKKHE 2950
LE AWV RR +LD CLELQLF+RDCEQA+ WM+AREAFL ED S D+VE+LIKKHE
Sbjct: 781 DLEKAWVQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHE 840
Query: 2949 DFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLG 2770
DFDKAIN QEEKI L+ FA+ LI +HY + +R+++LDRW LK +I+KR KLG
Sbjct: 841 DFDKAINVQEEKIAALQAFADQLIAVDHYAKGDIANRRNEVLDRWRRLKAQMIEKRSKLG 900
Query: 2769 ESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAA 2590
ESQTLQQFSRD DEIE W++EK Q A +E+Y+DPTNIQ KHQK QAFEAELHAN+DRI
Sbjct: 901 ESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPTNIQSKHQKHQAFEAELHANADRIRG 960
Query: 2589 IIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVK 2410
+I GN+LIE C G E AV ARL AL DQW LV+ + EKS +LKEANKQ++F +K
Sbjct: 961 VIDMGNSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIK 1020
Query: 2409 DLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLEND 2230
D +FWL EVE LL SEDYGKDLASV NLLKKH LLEADI AH+DR+ ++N QADSL+ +
Sbjct: 1021 DFDFWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSS 1080
Query: 2229 QFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVS 2050
F Q+ E+R I R+ +K MAT RR KLS++ +HQFFRD+DDEESWIKEKKLLVS
Sbjct: 1081 AFDTSQVKEKRDTINGRFQKIKSMATSRRAKLSESHRLHQFFRDMDDEESWIKEKKLLVS 1140
Query: 2049 SDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRM 1870
S+DYGRDL GVQNLR+KH+R++ ELA+HEP + V G++L + + +G+++I++R+
Sbjct: 1141 SEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKL---SDDNTIGQEEIQQRL 1197
Query: 1869 EDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGV 1690
+ W +++ L R QRL+ES +Q F+ +VEEEEAW+NEK ++ S+++G+ +A +
Sbjct: 1198 AQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAI 1257
Query: 1689 QGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMA 1510
QGLLKKH+ F+ D +HK RV D+ G LI NHH +I + L ++ ++E A
Sbjct: 1258 QGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKVSDLEKAA 1317
Query: 1509 EGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGL 1330
R AKL +NSA+LQF WK DVVESWI EKE ++++D+GRDLSSVQ LLTKQE FDAGL
Sbjct: 1318 AQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGL 1377
Query: 1329 NAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXX 1150
AF+ EGI IT LKDQL++++H QS AIE RH ++++RW LLA+S R+
Sbjct: 1378 QAFQQEGIANITALKDQLLAAKHIQSKAIEARHASLMKRWTQLLANSATRKKKLLEAQSH 1437
Query: 1149 XXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEE 970
++E+L+L FAKKAS FNSWFENAEEDLTDPVRCNSLEEI+ALR+AH F+ SLSSA+
Sbjct: 1438 FRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQA 1497
Query: 969 DFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDK 790
DF QL +LDR+IKSF V NPYTWFTM+ALE+TWRNLQ+IIKERE EL +E +RQEENDK
Sbjct: 1498 DFNQLAELDRQIKSFRVASNPYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDK 1557
Query: 789 LRREFAKLANAFHAWLTNTRQEMMEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAM 610
LR+EFA+ ANAFH W+ TR M+E GTLE QL+A +RK +EI+A + QL++IE+ GA
Sbjct: 1558 LRQEFAQHANAFHQWIQETRSCMVEESGTLESQLEATKRKHQEIRAMRSQLKKIEDLGAA 1617
Query: 609 LERNLILDNRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMM 430
+E LILDN+YTEHSTVG+AQ WDQLDQL MRMQHNLEQQIQARN +GV+EEAL+EFSMM
Sbjct: 1618 MEEALILDNKYTEHSTVGLAQQWDQLDQLGMRMQHNLEQQIQARNTTGVTEEALKEFSMM 1677
Query: 429 FKHFDKEKTGRLDHQQFKSCLRALGYDLPMVDEGQPEPEFQRILDIVDPNRDGYVTLQEY 250
FKHFDK+K+GRL+HQ+FKSCLR+LGYDLPMV+EG+P+PEF+ ILD VDPNRDG+V+LQEY
Sbjct: 1678 FKHFDKDKSGRLNHQEFKSCLRSLGYDLPMVEEGEPDPEFEAILDTVDPNRDGHVSLQEY 1737
Query: 249 MAFMISKETENIQSSEEIEMAFRALSKEFRPYVTAEELYANLTPEQAEFCIRRMKPYMDA 70
MAFMIS+ETEN++SSEEIE AFRALS E +PYVT EELY NLT EQA++C+ MKPY+D
Sbjct: 1738 MAFMISRETENVKSSEEIESAFRALSSEGKPYVTKEELYQNLTREQADYCVSHMKPYVDG 1797
Query: 69 ISGRSIQGGLDYEQFVHALF 10
GR + DY +F +LF
Sbjct: 1798 -KGRELPTAFDYVEFTRSLF 1816
Score = 676 bits (1744), Expect = 0.0
Identities = 422/1253 (33%), Positives = 653/1253 (51%), Gaps = 106/1253 (8%)
Frame = -1
Query: 6876 IKKRLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGM 6697
+ R++++ L+ + L+++ K R+ +E+ WI EKE +T E++G
Sbjct: 414 VSLRMKQVEELYQSLLELGEKRKGMLEKSCKKFMLFREANELQQWITEKEAALTNEEVGA 473
Query: 6696 DLEHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEG-HSEHDQIYKKRD------- 6541
DLE VE+LQ+KFDDF K+L ++ R+ +IN+ A+ L EG +E Q ++++
Sbjct: 474 DLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYGAMPR 533
Query: 6540 ----------------------------DVNDAWHRLNTLAATRKEGLFGAHQVQRFNRD 6445
++N+ W L LA R + L AH+VQRF+RD
Sbjct: 534 DEADSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRD 593
Query: 6444 ADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAE 6265
ADET WI EK+ AL++D+YG DL +VQALQRKHEG ERDLAAL K+ L + A +L +
Sbjct: 594 ADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAQRLIQ 653
Query: 6264 THPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAV 6085
+HP+ AE + +K + AW +L ++A RK L S L RFL+D+RDL+SWI ++ +
Sbjct: 654 SHPESAEDLKEKCTELNQAWTSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGL 713
Query: 6084 IGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLE 5905
+ +DELAKDV GAEALLE HQEH+ EIDARA +F GQ+L+ G SPE++EKL+
Sbjct: 714 VSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKEKLD 773
Query: 5904 KLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVE 5725
LD E++ L W +RR++ + C++LQLF+RD EQAE WM +EAFL D GDSLDSVE
Sbjct: 774 ILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVE 833
Query: 5724 HLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXX 5545
LIKKHEDF+K++ QEEKI AL FA +LI HYA D+A
Sbjct: 834 ALIKKHEDFDKAINVQEEKIAALQAFADQLIAVDHYAKGDIANRRNEVLDRWRRLKAQMI 893
Query: 5544 XRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQELKA 5365
+ + L ES Q F RD DE+ +WI+EKL TA D+SY DPTNI+ K QKH FE EL A
Sbjct: 894 EKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPTNIQSKHQKHQAFEAELHA 953
Query: 5364 NENRLDDIRSTGEQIIDSGHFAA--DHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQ 5191
N +R+ + G +I+ G A D + RL + + W LV + +K KL+EA +Q
Sbjct: 954 NADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQ 1013
Query: 5190 QFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLA 5011
FN I+D + WLSE+E +ASEDYGKDL SV NL KK L+E+D +AH DR+ + A
Sbjct: 1014 NFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQA 1073
Query: 5010 QQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIR 4831
F+ + K++ + R+ ++ R+ KL ESH+ +Q FRD++DE +WI+
Sbjct: 1074 DSLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKLSESHRLHQFFRDMDDEESWIK 1133
Query: 4830 EKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEI 4651
EK+ + S + GRDL GVQNL KK + L AE+A H+ I+ V + EI
Sbjct: 1134 EKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGQEEI 1193
Query: 4650 RDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKD 4471
+ +LAQ ++W+ LK A R L++SL+ Q++++ E +AW++EK +V S DYG
Sbjct: 1194 QQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDT 1253
Query: 4470 EDSAEALLKKHRALLSD--------------------------------LEAFKGTIEDL 4387
+ + LLKKH A +D ++ G + DL
Sbjct: 1254 LAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKVSDL 1313
Query: 4386 RKQASQCKYQEQPMGQLGRDCVLALYDYQEK------SPREVSMKKGD-------VLTLL 4246
K A+Q K +L + ++++ +E S+K D V TLL
Sbjct: 1314 EKAAAQRK------AKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLL 1367
Query: 4245 NASNRDWWKVEVNDRQGFVPAAYVKRIEPGTAQQHAQQQVNSIGGKQSEIEDKYQRLMML 4066
++ ++G +K + A +H Q + +I + + + ++ +L+
Sbjct: 1368 TKQETFDAGLQAFQQEGIANITALK--DQLLAAKHIQSK--AIEARHASLMKRWTQLLAN 1423
Query: 4065 GETRKRKLEEACKGYQ--------LLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQK 3910
TRK+KL EA ++ ++A+ W ++ E LE+++ L++
Sbjct: 1424 SATRKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEIKALRE 1483
Query: 3909 KFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXX 3730
D F+ L + + ++ ++ + S + + +E L WR L
Sbjct: 1484 AHDAFRSSLSSAQADFNQLAELDRQIKSF-RVASNPYTWFTMEALEETWRNLQKIIKERE 1542
Query: 3729 XQLGS---------------AHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQAL 3595
+L A FH+ + ETR + E+ L+S+ ++A
Sbjct: 1543 LELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRSCMVEESGTLESQ--------LEAT 1594
Query: 3594 QRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRL 3436
+RKH+ ++ A+ ++K +++ + ++ + L +QW++L
Sbjct: 1595 KRKHQ----EIRAMRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQQWDQL 1643
Score = 481 bits (1237), Expect = e-133
Identities = 409/1697 (24%), Positives = 748/1697 (43%), Gaps = 116/1697 (6%)
Frame = -1
Query: 6543 DDVNDAWHRLNTLAATRKEG--LFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLN 6370
++V W +L L AT +G L A+Q Q+FNR+ ++ W+ E + L+SDDYG+DL
Sbjct: 2 NEVISLWKKL--LEATELKGIKLREANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLT 59
Query: 6369 NVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKE 6190
NVQ LQ+KH E D+AA + ++ + +A + + AE I +K + A + ALKE
Sbjct: 60 NVQNLQKKHALLEADVAAHQDRIDGITIQARQFQDAGHFDAENIKKKQEALVARYEALKE 119
Query: 6189 KAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKG 6010
RK L S +L + D D +WI + + + + KD+ G + LL+ HQ +
Sbjct: 120 PMVARKQKLADSLRLQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQA 179
Query: 6009 EIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMD 5830
EI G +VE G + +V+ KL +L+ + +L +RR E +
Sbjct: 180 EIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLSELNQKWEALKAKASQRRQDLEDSLQ 239
Query: 5829 LQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDE 5650
Q ++ D +AE+WM ++E + +TD G DS E L+KKHE L+A I AL E
Sbjct: 240 AQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALRE 299
Query: 5649 FATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSW 5470
A Q D+ + +E R+ + D +
Sbjct: 300 QAQSCRQQVAPMDDETGKELVLALYD--------------YQEKSPREVTMKKGDILTLL 345
Query: 5469 ITEKLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHF---- 5302
+ + RD ++ + +G + + + + +R + + G + G
Sbjct: 346 NSTNKARHRDWWKVEVNDRQGFVPAAYVKKLDPAQSASRENLLEEQGSIALRQGQIDNQT 405
Query: 5301 ----AADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQ 5134
A + R++QV L+ L++ K+ L ++ + R +++ W++E E
Sbjct: 406 RITKEAGSVSLRMKQVEELYQSLLELGEKRKGMLEKSCKKFMLFREANELQQWITEKEAA 465
Query: 5133 VASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPV-IVRKQ 4957
+ +E+ G DL V+ LQKK + D A+ R+ I ++A+ + E V V++Q
Sbjct: 466 LTNEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQ 525
Query: 4956 E-----------------------------------NLQQRYNALRDPLEKRKRKLGESH 4882
E L +R+ +L+ E+R + LG +H
Sbjct: 526 EVYGAMPRDEADSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAH 585
Query: 4881 QGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVS 4702
+ + RD ++ WI EK Q + N G DL VQ L +K + ++A ++ S+
Sbjct: 586 EVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLG 645
Query: 4701 SAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADA 4522
A +IQ A ++++K +L W L +A++R+ L DS ++LSD + +
Sbjct: 646 ETAQRLIQSHPESAEDLKEKCTELNQAWTSLGKRADQRKAKLGDSHDLQRFLSDFRDLMS 705
Query: 4521 WMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQC-------- 4366
W++ +V S + KD AEALL++H+ ++++A GT + + Q
Sbjct: 706 WINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYAS 765
Query: 4365 ------------------KYQEQPMGQLGRDCVLALYDYQ-EKSPREVSMKKGDVLTLLN 4243
K Q L L L+ E++ ++ ++ + T
Sbjct: 766 PEIKEKLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTEDK 825
Query: 4242 ASNRDWWKVEVNDRQGFVPAAYVKRIEPGTAQQHAQQQV-------NSIGGKQSEIEDKY 4084
+ D + + + F A V+ + Q A Q + I +++E+ D++
Sbjct: 826 GDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAVDHYAKGDIANRRNEVLDRW 885
Query: 4083 QRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKF 3904
+RL ++ KL E+ Q R+ +++ WI S + A E D ++ +K
Sbjct: 886 RRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWI-SEKLQTASDESYKDPTNIQSKHQKH 944
Query: 3903 DDFKGDLKANEVRLQEMNQIATALTSVGQ---TETAVRIRQQIEDLNARWRALXXXXXXX 3733
F+ +L AN R++ + + +L G +E AV+ R + L +W+ L
Sbjct: 945 QAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKAR--LAALADQWQFLVQKSAEK 1002
Query: 3732 XXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAAL 3553
+L A++ Q F+ + + W+ E + L SED+G+DL SV L +KH+ +E D++A
Sbjct: 1003 SQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAH 1062
Query: 3552 GDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFL 3373
D++K L+ +A+ L S Q+ + + +N ++ ++ S A +R+ KL +S+ +F
Sbjct: 1063 EDRLKDLNSQADSLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKLSESHRLHQFF 1122
Query: 3372 SDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQL 3193
D D WI LVSS++ D+TG + L ++H+ E+ + Q G +L
Sbjct: 1123 RDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKL 1182
Query: 3192 LNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSARE 3013
+ + +I+ RL E K L+ AR L++ LE Q F + E+ + W++ +
Sbjct: 1183 SDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKM 1242
Query: 3012 AFLAQEDPSGDN---VESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTR 2842
+A ED GD ++ L+KKHE F+ ++++ + + LIK N++ ++
Sbjct: 1243 TLVASED-YGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISS 1301
Query: 2841 KRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENY-RDPT 2665
K + + + L++A Q++ KL E+ QF+ AD +E+W+ EK + ++Y RD +
Sbjct: 1302 KMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLS 1361
Query: 2664 NIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLL 2485
++Q KQ+ F+A L A A I A + + AK + A+ AR +L +W L
Sbjct: 1362 SVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSK-AIEARHASLMKRWTQL 1420
Query: 2484 VKTTTEKSYRLKEANKQ--------KSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVEN 2329
+ + + +L EA +F W E L L ++
Sbjct: 1421 LANSATRKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEIKA 1480
Query: 2328 LLKKHSLLEADIVAHQ---DRVGEMNEQADSL--------------LENDQFQGQQIAER 2200
L + H + + + Q +++ E++ Q S LE Q+I +
Sbjct: 1481 LREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFTMEALEETWRNLQKIIKE 1540
Query: 2199 RKLIADRYDGVKKMATDRRDKLSK--ALNVHQFFRDIDDEESWIKEKKLLVSS--DDYGR 2032
R+L + ++ + DKL + A + + F + I + S + E+ + S + R
Sbjct: 1541 RELELQK----EQRRQEENDKLRQEFAQHANAFHQWIQETRSCMVEESGTLESQLEATKR 1596
Query: 2031 DLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQS 1852
++ +R + ++I+ A+ E + L E A+ DQ+ RM+ +
Sbjct: 1597 KHQEIRAMRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQQWDQLDQLGMRMQHNLEQ 1656
Query: 1851 WGQIRDLTGNRHQRLDE 1801
Q R+ TG + L E
Sbjct: 1657 QIQARNTTGVTEEALKE 1673
Score = 466 bits (1199), Expect = e-129
Identities = 384/1627 (23%), Positives = 713/1627 (43%), Gaps = 105/1627 (6%)
Frame = -1
Query: 6864 LEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEH 6685
+ E+ +LW KGIKL++A + F R ++I W+ E E ++ ++D G DL +
Sbjct: 1 MNEVISLWKKLLEATELKGIKLREANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTN 60
Query: 6684 VEILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTL 6505
V+ LQ+K ++ HQ RI+ I A + + GH + + I KK++ + + L
Sbjct: 61 VQNLQKKHALLEADVAAHQDRIDGITIQARQFQDAGHFDAENIKKKQEALVARYEALKEP 120
Query: 6504 AATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERD 6325
RK+ L + ++Q+ RD ++ WI EK+ +S + G+DL VQ L +KH+ + +
Sbjct: 121 MVARKQKLADSLRLQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAE 180
Query: 6324 LAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQL 6145
+A E ++ + ++ + + E AE + K + W ALK KA R+ LE S Q
Sbjct: 181 IAGHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLSELNQKWEALKAKASQRRQDLEDSLQA 240
Query: 6144 HRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASA 5965
++ AD + SW+ + + ++G+ + KD AEALL+ H+ ++ A S
Sbjct: 241 QQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQ 300
Query: 5964 GQKLVEMGIPESPEVQEKLEKLDH---EKSSLLGLWEERRILYEQCMDLQLFYRDTEQAE 5794
Q + P E ++L + EKS ++ IL + +RD + E
Sbjct: 301 AQSCRQQVAPMDDETGKELVLALYDYQEKSPREVTMKKGDILTLLNSTNKARHRDWWKVE 360
Query: 5793 TWMNKQEAFLANTDLGDSLDSVEHLIKKH-EDFEKSLAAQEEKINALDEFATKLIQGQHY 5617
+N ++ F+ + LD + +++ + + S+A ++ +I+ +
Sbjct: 361 --VNDRQGFVPAAYV-KKLDPAQSASRENLLEEQGSIALRQGQIDNQTRITKE------- 410
Query: 5616 AADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEK-LSTARD 5440
A V+ R L++S K+ R+ +E+ WITEK + +
Sbjct: 411 -AGSVSLRMKQVEELYQSLLELGEKRKGMLEKSCKKFMLFREANELQQWITEKEAALTNE 469
Query: 5439 DSYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAAD----------- 5293
+ D + +K +F+++LKANE+RL DI E + G A +
Sbjct: 470 EVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYG 529
Query: 5292 -------------------------HIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQ 5188
+ ++++N W L ++ L A Q+
Sbjct: 530 AMPRDEADSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQR 589
Query: 5187 FNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQ 5008
F+R+ ++ + W+ E + +++YG DL SVQ LQ+K E D A D+V+ + + AQ
Sbjct: 590 FHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAQ 649
Query: 5007 QFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIRE 4828
+ + +A + K L Q + +L ++RK KLG+SH + D D ++WI
Sbjct: 650 RLIQSHPESAEDLKEKCTELNQAWTSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWING 709
Query: 4827 KEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIR 4648
+ S +D+ G + L+++ Q EI ++ ++ GH+ +PEI+
Sbjct: 710 IRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIK 769
Query: 4647 DKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDE 4468
+KL L L+ +RR LD L+ + D +A+ WM+ +E + + D G
Sbjct: 770 EKLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSL 829
Query: 4467 DSAEALLKKHRALLSDLEAFKGTIEDLRKQASQ-CKYQEQPMGQLG--RDCVLALYDYQE 4297
DS EAL+KKH + + I L+ A Q G + R+ VL + +
Sbjct: 830 DSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAVDHYAKGDIANRRNEVLDRWRRLK 889
Query: 4296 KSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIEPGTAQ-QHAQQQV-- 4126
E K G+ TL S RD ++E + A+ +P Q +H + Q
Sbjct: 890 AQMIEKRSKLGESQTLQQFS-RDVDEIEAWISEKLQTASDESYKDPTNIQSKHQKHQAFE 948
Query: 4125 ------------------------------NSIGGKQSEIEDKYQRLMMLGETRKRKLEE 4036
+++ + + + D++Q L+ + +KL+E
Sbjct: 949 AELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKE 1008
Query: 4035 ACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQE 3856
A K D W+ EA+ A ++ G DL V L KK + D+ A+E RL++
Sbjct: 1009 ANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKD 1068
Query: 3855 MNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDE 3676
+N A +L + +T+ +++++ + +N R++ + +L +H + +F RD+D+
Sbjct: 1069 LNSQADSLMTSSAFDTS-QVKEKRDTINGRFQKIKSMATSRRAKLSESHRLHQFFRDMDD 1127
Query: 3675 TRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHP 3496
WI+EK + SED+GRDL VQ L++KH+ +E +LAA I+ + + +L +
Sbjct: 1128 EESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNT 1187
Query: 3495 EAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSS 3316
E+I + E W L A R ++L +S +YQ+F+++ + WI LV+S
Sbjct: 1188 IGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVAS 1247
Query: 3315 QELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVN 3136
++ + + + LL++H+ + T+ G L+ +++ +I ++++G+N
Sbjct: 1248 EDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGLN 1307
Query: 3135 EARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGD--NVESLI 2962
LE A R+ LD+ F + ++W+ +E L +D D +V++L+
Sbjct: 1308 GKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLL 1367
Query: 2961 KKHEDFDKAINT-QEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQK 2785
K E FD + Q+E I + + L+ H S A+ + ++ RW L +
Sbjct: 1368 TKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHASLMKRWTQLLANSATR 1427
Query: 2784 RFKLGESQT--------LQQFSRDADEIENWMTEKFQIAQEENYRDPT------NIQQKH 2647
+ KL E+Q+ F++ A +W EE+ DP I+
Sbjct: 1428 KKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFEN-----AEEDLTDPVRCNSLEEIKALR 1482
Query: 2646 QKQQAFEAEL---HANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKT 2476
+ AF + L A+ +++A + + I++ + ++AL + W L K
Sbjct: 1483 EAHDAFRSSLSSAQADFNQLAEL----DRQIKSFRVASNPYTWFT-MEALEETWRNLQKI 1537
Query: 2475 TTEKSYRL-KEANKQ-------KSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLK 2320
E+ L KE +Q + F W+ E + E+ G + +E +
Sbjct: 1538 IKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRSCM-VEESGTLESQLEATKR 1596
Query: 2319 KHSLLEA 2299
KH + A
Sbjct: 1597 KHQEIRA 1603
Score = 452 bits (1163), Expect = e-125
Identities = 395/1703 (23%), Positives = 741/1703 (43%), Gaps = 127/1703 (7%)
Frame = -1
Query: 7173 EVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILE-KLQTAQEENFRDPSNLQ 6997
EV+ + + ++ K +L EA Q Q F R+ +++ +W+ E + A ++ +D +N+Q
Sbjct: 3 EVISLWKKLLEATELKGIKLREANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTNVQ 62
Query: 6996 AKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXX 6817
+KH EA+V AH I + HF +E+IKK+ E L A +
Sbjct: 63 NLQKKHALLEADVAAHQDRIDGITIQARQFQDAGHFDAENIKKKQEALVARYEALKEPMV 122
Query: 6816 XKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELG 6637
+ KL +L+L R ++ WIREKE + + G DL V+ L +K E+
Sbjct: 123 ARKQKLADSLRLQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIA 182
Query: 6636 NHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQR 6457
H+ RI + Q + +VEEGH + + K ++N W L A+ R++ L + Q Q+
Sbjct: 183 GHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLSELNQKWEALKAKASQRRQDLEDSLQAQQ 242
Query: 6456 FNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAH 6277
+ DA+E +W+ EK+ + S DYG+D ++ +AL +KHE DL+A + L ++A
Sbjct: 243 YFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQ 302
Query: 6276 KLA--------ETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYR 6121
ET + A++ + + +E + D L ++ A +R
Sbjct: 303 SCRQQVAPMDDETGKELVLALYDYQEKSP------REVTMKKGDILTLLNSTNK--ARHR 354
Query: 6120 DLISW----IGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSF-NQTASAGQK 5956
D W + D + + A + K A E+ E +G I R NQT
Sbjct: 355 D---WWKVEVNDRQGFVPAAYVKKLDPAQSASRENLLEEQGSIALRQGQIDNQTRIT--- 408
Query: 5955 LVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQ 5776
E+ V ++++++ SLL L E+R+ + E+ + +R+ + + W+ ++
Sbjct: 409 ------KEAGSVSLRMKQVEELYQSLLELGEKRKGMLEKSCKKFMLFREANELQQWITEK 462
Query: 5775 EAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKL------------I 5632
EA L N ++G L+ VE L KK +DF+K L A E ++ +++ A L +
Sbjct: 463 EAALTNEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAV 522
Query: 5631 QGQH-YAA--DDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKR---------------- 5509
Q Q Y A D A+ N++KE +R
Sbjct: 523 QQQEVYGAMPRDEADSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLG 582
Query: 5508 -----QTFDRDCDEMVSWITEKLSTARDDSY-LDPTNIRGKLQKHINFEQELKANENRLD 5347
Q F RD DE WI EK D+Y D +++ +KH FE++L A ++++
Sbjct: 583 SAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVN 642
Query: 5346 DIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIED 5167
+ T +++I S +A+ + ++ ++N W L +++ AKL ++ + Q+F + D
Sbjct: 643 SLGETAQRLIQSHPESAEDLKEKCTELNQAWTSLGKRADQRKAKLGDSHDLQRFLSDFRD 702
Query: 5166 VEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEH 4987
+ +W++ + G V+S++ KD+ + L ++ ++ +A +Q QQ H
Sbjct: 703 LMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGH 762
Query: 4986 FNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGS 4807
+ +P I K + L Q L +R+ L + RD E W+ +E +
Sbjct: 763 YASPEIKEKLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNT 822
Query: 4806 TNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLR 4627
++G L V+ LIKK + I + +I ++ + A+ +I H+ +I ++ ++
Sbjct: 823 EDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAVDHYAKGDIANRRNEVL 882
Query: 4626 DNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALL 4447
D WR LK++ ++R+ L +S Q+ D +E +AW+SEK Y KD + ++
Sbjct: 883 DRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESY-KDPTNIQSKH 941
Query: 4446 KKHRALLSDLEA----FKGTIE---DLRKQASQCKYQEQPMGQLGRDCVLALYDYQEKSP 4288
+KH+A ++L A +G I+ L ++ + ++ +L + Q+ +
Sbjct: 942 QKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQFLVQKSAE 1001
Query: 4287 REVSMKKGDVLTLLNASNR--DWWKVEVN-------------------DRQGFVPA---A 4180
+ +K+ + N + D+W EV + + A A
Sbjct: 1002 KSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISA 1061
Query: 4179 YVKRIEPGTAQQHAQQ-----QVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQL 4015
+ R++ +Q + + + K+ I ++Q++ + +R+ KL E+ + +Q
Sbjct: 1062 HEDRLKDLNSQADSLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKLSESHRLHQF 1121
Query: 4014 LREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATA 3835
R+ +D WIK ++ + + ++ G DL V+ L+KK + +L A+E +Q +
Sbjct: 1122 FRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKK 1181
Query: 3834 LT---SVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDW 3664
L+ ++GQ E R+ Q +E W+ L +L + E Q+F +V+E W
Sbjct: 1182 LSDDNTIGQEEIQQRLAQFVE----HWKELKQLAAARGQRLEESLEYQQFVANVEEEEAW 1237
Query: 3663 IQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAE 3484
I EK + SED+G L ++Q L +KHE E D D++ + L + + E
Sbjct: 1238 INEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEE 1297
Query: 3483 QIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELA 3304
I + LN + + L A RK KL ++ + +F + WI + + +
Sbjct: 1298 NISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYG 1357
Query: 3303 NDVTGAEALLERHQEYRTEIDSRAATFQAFDQFG--------NQLLNSHHYAAGDIENR- 3151
D++ + LL + + + A QAF Q G +QLL + H + IE R
Sbjct: 1358 RDLSSVQTLLTKQETF-------DAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARH 1410
Query: 3150 ----------LQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLA 3001
L +K L +A R + D L F + ++W E L
Sbjct: 1411 ASLMKRWTQLLANSATRKKKLLEAQSHFRKVEDLFL---TFAKKASAFNSWFENAEEDLT 1467
Query: 3000 QEDP----SGDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRD 2833
DP S + +++L + H+ F ++++ + L + +P +
Sbjct: 1468 --DPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFTME 1525
Query: 2832 QILDRWNGLKEALIQKRFKLGESQ--------TLQQFSRDADEIENWMTEKFQIAQEENY 2677
+ + W L++ + ++ +L + Q Q+F++ A+ W+ E EE+
Sbjct: 1526 ALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRSCMVEESG 1585
Query: 2676 RDPTNIQ---QKHQKQQAFEAELHANSDRIAAIIQA---GNNLIENAKCGGGEAAVSARL 2515
+ ++ +KHQ+ +A ++L D AA+ +A N E++ G
Sbjct: 1586 TLESQLEATKRKHQEIRAMRSQLKKIEDLGAAMEEALILDNKYTEHSTVG---------- 1635
Query: 2514 KALNDQWDLLVKTTTEKSYRLKE 2446
L QWD L + + L++
Sbjct: 1636 --LAQQWDQLDQLGMRMQHNLEQ 1656
Score = 402 bits (1034), Expect = e-110
Identities = 376/1605 (23%), Positives = 690/1605 (42%), Gaps = 119/1605 (7%)
Frame = -1
Query: 7200 ADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEEN 7021
A++I ++++ ++ Y K+ ++ +L ++ + Q RD ++ WI EK A N
Sbjct: 100 AENIKKKQEALVARYEALKEPMVARKQKLADSLRLQQLFRDVEDEETWIREKEPIAASTN 159
Query: 7020 F-RDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHAL 6844
+D +Q ++KH+A +AE+ H I + + GNAM++ HFA+E +K +L EL+
Sbjct: 160 RGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLSELNQK 219
Query: 6843 WXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRK 6664
W + L+ +L+ + +E W+REKE V + D G D + E L +K
Sbjct: 220 WEALKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKK 279
Query: 6663 FDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEG 6484
+ + +L + I + + A ++ D+ K+ + + T K+G
Sbjct: 280 HEALMSDLSAYGSSIQALREQAQSCRQQVAPMDDETGKELVLALYDYQEKSPREVTMKKG 339
Query: 6483 -LFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEG 6307
+ R D + ++ Y + L+ Q+ R++ E+ AL
Sbjct: 340 DILTLLNSTNKARHRDWWKVEVNDRQ-GFVPAAYVKKLDPAQSASRENLLEEQGSIALRQ 398
Query: 6306 KMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLAD 6127
+ + K A ++ + + + +L E + RK LE+S + +
Sbjct: 399 GQIDNQTRITK-------EAGSVSLRMKQVEELYQSLLELGEKRKGMLEKSCKKFMLFRE 451
Query: 6126 YRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEI---DARADSFNQTA----S 5968
+L WI + +A + +E+ D+ E L + + + ++ ++R N+ A S
Sbjct: 452 ANELQQWITEKEAALTNEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLES 511
Query: 5967 AGQKLVEMGIPESPEVQ-----------------------------EKLEKLDHEKSSLL 5875
G E+ + EV +++L+ SL
Sbjct: 512 EGLMAEEVQAVQQQEVYGAMPRDEADSKTASPWKSARLMVHTVATFNSIKELNERWRSLQ 571
Query: 5874 GLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFE 5695
L EER L ++Q F+RD ++ + W+ ++ L + G L SV+ L +KHE FE
Sbjct: 572 QLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFE 631
Query: 5694 KSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESY 5515
+ LAA +K+N+L E A +LIQ +A+D+ E R L +S+
Sbjct: 632 RDLAALGDKVNSLGETAQRLIQSHPESAEDLKEKCTELNQAWTSLGKRADQRKAKLGDSH 691
Query: 5514 KRQTFDRDCDEMVSWITE-KLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDIR 5338
Q F D +++SWI + + D+ D T L++H E+ A
Sbjct: 692 DLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFE 751
Query: 5337 STGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEA 5158
G+Q++ GH+A+ I ++L ++ +L A ++ L Q F+R+ E E
Sbjct: 752 QFGQQLLAHGHYASPEIKEKLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAEN 811
Query: 5157 WLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNA 4978
W++ E + +ED G L SV+ L KK + N +++ ++ A Q +H+
Sbjct: 812 WMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAVDHYAK 871
Query: 4977 PVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNR 4798
I ++ + R+ L+ + +++ KLGES Q RD+++ AWI EK Q A S
Sbjct: 872 GDIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTA-SDES 930
Query: 4797 GRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPE--IRDKLAQLRD 4624
+D +Q+ +K QA AE+ + +I V N +I++G E ++ +LA L D
Sbjct: 931 YKDPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALAD 990
Query: 4623 NWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLK 4444
W+ L K+ ++ L ++ + + + + D W+SE E ++ S DYGKD S LLK
Sbjct: 991 QWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLK 1050
Query: 4443 KHRALLSDLEAFKGTIEDLRKQA-----------SQCK---------YQEQPMGQLGRDC 4324
KH+ L +D+ A + ++DL QA SQ K +Q+ R
Sbjct: 1051 KHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRA 1110
Query: 4323 VLA----LYD-YQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIEP 4159
L+ L+ +++ E +K+ +L RD V+ N R+ KR+E
Sbjct: 1111 KLSESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQ-NLRKKH------KRLEA 1163
Query: 4158 G-TAQQHAQQQVNSIGGK--------QSEIEDK-------YQRLMMLGETRKRKLEEACK 4027
A + A Q V G K Q EI+ + ++ L L R ++LEE+ +
Sbjct: 1164 ELAAHEPAIQGVLDTGKKLSDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLE 1223
Query: 4026 GYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQ 3847
Q + + WI + + A ++ G L ++ L KK + F+ D ++ R+ ++
Sbjct: 1224 YQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCT 1283
Query: 3846 IATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRD 3667
L I +++ LN + L +L +F+ D
Sbjct: 1284 NGQDLIKKNNHHEE-NISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVES 1342
Query: 3666 WIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDK-IKSLDEKANRLRQSHPEA 3490
WI EK+++L ++D+GRDL SVQ L K E + L A + I ++ ++L +
Sbjct: 1343 WIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQ 1402
Query: 3489 AEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDY--------RDLMQWIASM 3334
++ I L ++W +L + + RK+KLL++ + R + D W +
Sbjct: 1403 SKAIEARHASLMKRWTQLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFENA 1462
Query: 3333 NQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQL----LNSHHYAAG 3166
+ ++ N + +AL E H +R+ + S A F + Q+ + S+ Y
Sbjct: 1463 EEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWF 1522
Query: 3165 DIENRLQGVNEARKGLEDAWVARRNIL-DQCLELQLFYRDCEQAD--------------T 3031
+E LE+ W + I+ ++ LELQ R E+ D
Sbjct: 1523 TME-----------ALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQ 1571
Query: 3030 WMSAREAFLAQEDPSGDN-VESLIKKHEDFDKAINTQEEKIKGL-KLFAESLIKNNHYDS 2857
W+ + + +E + ++ +E+ +KH++ +A+ +Q +KI+ L E+LI +N Y
Sbjct: 1572 WIQETRSCMVEESGTLESQLEATKRKHQEI-RAMRSQLKKIEDLGAAMEEALILDNKYTE 1630
Query: 2856 PAVT------RKRDQILDRWNGLKEALIQKRFKLG-ESQTLQQFS 2743
+ + DQ+ R E IQ R G + L++FS
Sbjct: 1631 HSTVGLAQQWDQLDQLGMRMQHNLEQQIQARNTTGVTEEALKEFS 1675
Score = 340 bits (873), Expect = 2e-91
Identities = 250/940 (26%), Positives = 429/940 (45%), Gaps = 15/940 (1%)
Frame = -1
Query: 7137 SQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENF-RDPSNLQAKIQKHEAFEAE 6961
++ + L A + Q F RDADE WI EK Q +N+ D +++QA +KHE FE +
Sbjct: 574 AEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERD 633
Query: 6960 VQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKL 6781
+ A + +L +T +IQ + ++E +K++ EL+ W + KL + L
Sbjct: 634 LAALGDKVNSLGETAQRLIQSHPESAEDLKEKCTELNQAWTSLGKRADQRKAKLGDSHDL 693
Query: 6780 LHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQA 6601
F+ +++ WI V+++++ D+ E L + + E+ Q
Sbjct: 694 QRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQF 753
Query: 6600 ADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWI 6421
+L+ GH +I +K D ++ L R+ L ++Q F+RD ++ W+
Sbjct: 754 GQQLLAHGHYASPEIKEKLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWM 813
Query: 6420 GEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKL-AETHPDRAE 6244
++ L+++D G L++V+AL +KHE ++ + E K+ L+ A +L A H + +
Sbjct: 814 AAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAVDHYAKGD 873
Query: 6243 AIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELA 6064
+++N + W LK + ++ L S L +F D ++ +WI + K +DE
Sbjct: 874 IANRRN-EVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISE-KLQTASDESY 931
Query: 6063 KDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPE--VQEKLEKLDHE 5890
KD ++ + HQ + E+ A AD G L+E G E V+ +L L +
Sbjct: 932 KDPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQ 991
Query: 5889 KSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKK 5710
L+ E+ ++ Q F + + W+++ EA LA+ D G L SV +L+KK
Sbjct: 992 WQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKK 1051
Query: 5709 HEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNA 5530
H+ E ++A E+++ L+ A L+ + V E R
Sbjct: 1052 HQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAK 1111
Query: 5529 LKESYKRQTFDRDCDEMVSWITE-KLSTARDDSYLDPTNIRGKLQKHINFEQELKANENR 5353
L ES++ F RD D+ SWI E KL + +D D T ++ +KH E EL A+E
Sbjct: 1112 LSESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPA 1171
Query: 5352 LDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNI 5173
+ + TG+++ D + I RL Q W EL +G +L E+ QQF N+
Sbjct: 1172 IQGVLDTGKKLSDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANV 1231
Query: 5172 EDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEE 4993
E+ EAW++E VASEDYG L ++Q L KK E+DF H DRV+ + Q ++
Sbjct: 1232 EEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKK 1291
Query: 4992 EHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVA 4813
+ + I K + L + + L +RK KL E+ Q + +WI EKE
Sbjct: 1292 NNHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSL 1351
Query: 4812 GSTNRGRDLIGVQNLIKKQQALIAEI-ANHDSQIESVSSAANDMIQQGHFLAPEIRDKLA 4636
+ + GRDL VQ L+ KQ+ A + A I ++++ + ++ H + I + A
Sbjct: 1352 KTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHA 1411
Query: 4635 QLRDNWRILKSKAEKRRTDLDDSLQAH------QYLSDANEADA---WMSEKEPIVGSTD 4483
L W L + + R+ L ++ Q+H +L+ A +A A W E +
Sbjct: 1412 SLMKRWTQLLANSATRKKKLLEA-QSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPV 1470
Query: 4482 YGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCK 4363
+ +AL + H A S L + + L + Q K
Sbjct: 1471 RCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIK 1510
Score = 281 bits (718), Expect = 2e-73
Identities = 196/762 (25%), Positives = 341/762 (44%), Gaps = 23/762 (3%)
Frame = -1
Query: 7194 DIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENFR 7015
DI RR EVL + K KR +L E++ Q F RD DE+ WI EKLQTA +E+++
Sbjct: 873 DIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYK 932
Query: 7014 DPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEH--IKKRLEELHALW 6841
DP+N+Q+K QKH+AFEAE+ A+A I + GN++I+ A +K RL L W
Sbjct: 933 DPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQW 992
Query: 6840 XXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKF 6661
K KL++A K +F + +W+ E E + +ED G DL V L +K
Sbjct: 993 QFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKH 1052
Query: 6660 DDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGL 6481
++ H+ R+ ++N AD L+ + Q+ +KRD +N + ++ ++A +R+ L
Sbjct: 1053 QLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKL 1112
Query: 6480 FGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKM 6301
+H++ +F RD D+ +WI EK L +SS+DYGRDL VQ L++KH+ E +LAA E +
Sbjct: 1113 SESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAI 1172
Query: 6300 LQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYR 6121
+ KL++ + E I Q+ W LK+ A R LE S + +F+A+
Sbjct: 1173 QGVLDTGKKLSDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVE 1232
Query: 6120 DLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMG 5941
+ +WI + ++ +++ +A + LL+ H+ + + D N + GQ L++
Sbjct: 1233 EEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKN 1292
Query: 5940 IPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLA 5761
+ K++ L+ + S L +R+ ++ F + E+W+ ++E L
Sbjct: 1293 NHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLK 1352
Query: 5760 NTDLGDSLDSVEHLIKKHEDFEKSLAA-QEEKINALDEFATKLIQGQHYAADDVAEXXXX 5584
D G L SV+ L+ K E F+ L A Q+E I + +L+ +H + +
Sbjct: 1353 TDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHAS 1412
Query: 5583 XXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTAR------DDSYLDP 5422
R L E+ Q+ R +++ +K S ++ DP
Sbjct: 1413 LMKRWTQLLANSATRKKKLLEA---QSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDP 1469
Query: 5421 T------NIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNN 5260
I+ + H F L + + + + QI + + + +
Sbjct: 1470 VRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFTMEALEE 1529
Query: 5259 LWNELVDATNKKGAKL-----REAGNE---QQFNRNIEDVEAWLSELEGQVASEDYGKDL 5104
W L ++ +L R+ N+ Q+F ++ W+ E + E
Sbjct: 1530 TWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRSCMVEES----- 1584
Query: 5103 VSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNA 4978
G +ES A + I+ + Q ++ E A
Sbjct: 1585 ----------GTLESQLEATKRKHQEIRAMRSQLKKIEDLGA 1616
Score = 107 bits (268), Expect = 3e-21
Identities = 78/312 (25%), Positives = 136/312 (43%), Gaps = 10/312 (3%)
Frame = -1
Query: 7197 DDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENF 7018
++I QR + + H+ K + + RLEE+ ++Q F + +E WI EK+ E++
Sbjct: 1191 EEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDY 1250
Query: 7017 RDP-SNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALW 6841
D + +Q ++KHEAFE + H + ++ G +I+ N+ E+I +++ L+
Sbjct: 1251 GDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKV 1310
Query: 6840 XXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKF 6661
+ KL + L F + D + WI EKE + +D G DL V+ L K
Sbjct: 1311 SDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQ 1370
Query: 6660 DDFLKELGNHQYR-INEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEG 6484
+ F L Q I I D+L+ H + I + + W +L +ATRK+
Sbjct: 1371 ETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHASLMKRWTQLLANSATRKKK 1430
Query: 6483 LFGAHQVQR--------FNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTER 6328
L A R F + A +W + L+ L ++AL+ H+
Sbjct: 1431 LLEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRS 1490
Query: 6327 DLAALEGKMLQL 6292
L++ + QL
Sbjct: 1491 SLSSAQADFNQL 1502
>gi|47211130|emb|CAF90368.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 2569
Score = 2141 bits (5548), Expect(2) = 0.0
Identities = 1154/2496 (46%), Positives = 1573/2496 (62%), Gaps = 181/2496 (7%)
Frame = -1
Query: 7218 IRILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQ 7039
+++LETA+DI RRQ+VL Y FK+ S +R +LE++ +FQ F+RDA+EL WI EKLQ
Sbjct: 6 VKVLETAEDIQDRRQQVLDRYRRFKELSVMRRQKLEDSYRFQCFRRDAEELEKWIQEKLQ 65
Query: 7038 TAQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLE 6859
A +EN++DPSNLQ K+QKH+AFEAEVQA+A TI LD+TGN MI HFASE I+ RLE
Sbjct: 66 IASDENYKDPSNLQGKLQKHQAFEAEVQANAGTIIKLDETGNLMISEGHFASETIRSRLE 125
Query: 6858 ELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVE 6679
ELH LW KG++L QA KL+ ++R+C++ L WI +KE T+E++G DLEHVE
Sbjct: 126 ELHRLWDLLLQKTKEKGLRLLQAQKLVQYLRECEDALDWISDKEAMATSEELGQDLEHVE 185
Query: 6678 ILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAA 6499
+LQ+KF++F +L H+ R+NE+NQ A KL++E H E + I +K+D+VN AW RL LA
Sbjct: 186 LLQKKFEEFQTDLAAHEERVNEVNQLAAKLIQESHPEVELIVRKQDEVNAAWQRLKGLAQ 245
Query: 6498 TRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLA 6319
R+ LFGA +VQRFNRD DET++WI EK+ ++SDD+GRDL +VQAL RKHEG ERDLA
Sbjct: 246 QRQGRLFGAAEVQRFNRDVDETISWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLA 305
Query: 6318 ALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHR 6139
ALE K+ L +A +L ETHP A I K D+ A W ++ A R L+ S++L R
Sbjct: 306 ALEDKVNTLGGDAGRLQETHPQNASQILLKKDELVANWEQIRTLAAERHARLDDSYRLQR 365
Query: 6138 FLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQ 5959
F AD+RDL SW+ +M+A+I ADELA DVAGAEALL+ HQEHKGEIDA DSF T AGQ
Sbjct: 366 FTADFRDLTSWVTEMQALIKADELANDVAGAEALLDRHQEHKGEIDAHEDSFRSTDEAGQ 425
Query: 5958 KLVEMGIPESPEVQEK----------------------------LEKLDHEKSSLLGLWE 5863
LV G S EV+EK L L EK +LL LWE
Sbjct: 426 ALVNTGHYASEEVKEKVGLPPDCPQTAGVVFSCVSRVCVCVRVQLGILSEEKEALLNLWE 485
Query: 5862 ERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLA 5683
RR YEQCMDLQLFYRDTEQ + WM+KQEAFL N DLGDSLDSVE L+KKHEDFEKSL+
Sbjct: 486 VRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEALLKKHEDFEKSLS 545
Query: 5682 AQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQT 5503
AQEEKI ALDEFATKLIQ HYA +DVA R AL++S+ Q
Sbjct: 546 AQEEKITALDEFATKLIQNNHYAKEDVATRRDALLSRRNALHERAQSRRAALEDSFHLQQ 605
Query: 5502 FDRDCDEMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQ 5323
F RD DE+ SWI EK+ TA D++Y DP+N++GK+QKH FE EL AN++R+D ++ +G+
Sbjct: 606 FFRDSDELKSWINEKMKTATDEAYKDPSNLQGKVQKHQAFEAELSANQSRIDALQKSGQD 665
Query: 5322 IIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEA----- 5158
+++ H+A+ + R+ +V++ W +L++AT K ++ + A QQ V
Sbjct: 666 LLERKHYASSEVARRMEEVSSQWKKLLEATELKASRGQPAAAVQQERGGHRAVAVRGGGP 725
Query: 5157 -WLSEL-EGQVASEDYGKDLVSVQNLQK-KIGLIE-SDFNAHNDRVDGIKQLAQQFQEEE 4990
L L +G + ++ + + GL+ + + DR+DGI A+QFQE
Sbjct: 726 PGLRRLRQGPDQRPEPAEEARAAGGRRGCSPGLLRVNSLISSQDRIDGISIQARQFQEAG 785
Query: 4989 HFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAG 4810
HF+A I RKQE L RY ALR P+ RK+KL +S + QLFRD+EDE WIREKE +A
Sbjct: 786 HFDADNIRRKQEALALRYEALRQPMATRKQKLSDSLRLQQLFRDVEDEETWIREKEPIAA 845
Query: 4809 STNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQL 4630
STNRG+DLIGVQNL+KK QAL AEI H+ +I++V+ M+++GHF +++ KL +L
Sbjct: 846 STNRGKDLIGVQNLLKKHQALQAEIVGHEPRIKAVTQKGETMVEEGHFAGEDVKVKLTEL 905
Query: 4629 RDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEAL 4450
W LK KA +R+ DL+DSLQA QY +DANEA++WM EKEPIVGSTDYGKDEDSAEAL
Sbjct: 906 HGRWDTLKLKASQRKQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEAL 965
Query: 4449 LKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQPMG-QLGRDCVLALYDYQEKSPREVSM 4273
LKKH AL+SDL A+ +I+ L++QA C+ Q P + G++ VLALYDYQEKSPREV+M
Sbjct: 966 LKKHEALMSDLSAYGSSIQGLKEQAQSCRQQVAPTDDETGKELVLALYDYQEKSPREVTM 1025
Query: 4272 KKGDVLTLLNASNR-----------------------------------------DWWKV 4216
KKGD+LTLLN++N+ DWWKV
Sbjct: 1026 KKGDILTLLNSTNKVERWLACSRAAGSAPPWWRLQVVGLAEPSSLHPMTCGLSWQDWWKV 1085
Query: 4215 EVNDRQGFVPAAYVKRIEPGTA-------QQHA-----QQQVN---------SIGGKQSE 4099
EVNDRQGFVPAAYVK+++P + ++H Q Q+ S+ + +
Sbjct: 1086 EVNDRQGFVPAAYVKKLDPNQSSSRENLLEEHGSIALRQDQIENQLVTKEACSVSVRMKQ 1145
Query: 4098 IEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEV 3919
+E+ Y L+ LGE RK LE++CK + L REAN+L +WI +E +E+G+DLEQVEV
Sbjct: 1146 VEELYANLLELGEKRKDMLEKSCKKFMLFREANELQQWIHEKEGTLTNEEVGSDLEQVEV 1205
Query: 3918 LQKKFDDFKGDLKANEVRLQEMNQIATALTSVG-QTETAVRIRQQIEDLNARWRALXXXX 3742
LQKKFDDF+ DLKANE RL+++N++A L S G E ++ Q+ +
Sbjct: 1206 LQKKFDDFQKDLKANESRLRDINKVAAELESEGLMAEETPMVQAQVPGVPP--------- 1256
Query: 3741 XXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDL 3562
G+ +R H+ ++Q++ + L A K E +
Sbjct: 1257 -------GARLAFRRQHQPHPLFFLFLQQQQELLG------------AAPGKDEADSKTA 1297
Query: 3561 AALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQ 3382
+ + ++ AN ++ +ELN +W L A +R L +
Sbjct: 1298 SPWKNVRLAVQTTAN-------------FNTIKELNNRWRSLQQLAEDRSHMLGSA---- 1340
Query: 3381 RFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFG 3202
D + +WI NQ +++ +D+ +AL +H+ + ++ + + +
Sbjct: 1341 --TRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETA 1398
Query: 3201 NQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMS 3022
+L+ SH A DI+ + +N A L R++ L +LQ F D +W++
Sbjct: 1399 ERLIQSHPEAVEDIKEKCSELNTAWSSLVGRADQRKDKLANSHDLQRFLSDFRDLMSWIN 1458
Query: 3021 AREAFLAQEDPSGD--NVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAV 2848
++ E+ + D E+L+++H++ I+ + + + F + L+ HY SP +
Sbjct: 1459 GIRGLVSSEELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLVRGHYASPEI 1518
Query: 2847 TRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDP 2668
+K + + L++A +Q+R L + LQ FSRD ++ ENWM + ++ D
Sbjct: 1519 QQKLEALEQERTHLEKAWVQRRMMLDQCLELQLFSRDCEQAENWMAAREAFLASDDKGDS 1578
Query: 2667 TN-IQQKHQKQQAFEAELHANSDRIAA-------IIQA---------------------- 2578
+ ++ +K + F+ ++ ++IAA +I A
Sbjct: 1579 LDSVEALIKKHEDFDKAINVQEEKIAALQSFADQLIGADHYAKAEIHSRCREVLDRASIR 1638
Query: 2577 ---------------------GNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKS 2461
GN LI+ C G E AV RL AL++QW LV + EKS
Sbjct: 1639 SIRRSRQSCTLTQTHPRGHRHGNALIQRGACAGSEDAVKTRLAALDEQWQFLVNKSAEKS 1698
Query: 2460 YRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQ 2281
+LKEANKQ++F +KD +FWL EVE LL SEDYGKDLASV NLLKKH LLEADI AH+
Sbjct: 1699 QKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHE 1758
Query: 2280 DRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFR 2101
DR+ ++N QADSL+ +D F Q+ ++R + R+ +K MA RR +L+++ +HQFFR
Sbjct: 1759 DRLKDLNSQADSLMASDAFDTSQVKDKRSGVNARFAKIKSMAATRRARLNESHRLHQFFR 1818
Query: 2100 DIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELL 1921
D+DDEESWIKEKKLLVSS+DYGRDL GVQNLR+KH+R++ EL +HEP + V G++L
Sbjct: 1819 DLDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELGAHEPAIQSVLDTGKKL- 1877
Query: 1920 RSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNE 1741
+ + +G+++I++R+ W +++DL+G R QRL+ES +Q F+ +VEEEEAW+NE
Sbjct: 1878 --SDDNTIGQEEIQQRLAQFVDHWKELKDLSGARGQRLEESLEYQQFVANVEEEEAWINE 1935
Query: 1740 KQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIK 1561
K ++ S+++G+ +A VQGLLKKH+ F+ D +H+ RV D+ + G LI NHH +I
Sbjct: 1936 KLNLVASEDYGDTLAAVQGLLKKHEAFETDFTVHRDRVGDVCSNGGELIKKNNHHVNNIS 1995
Query: 1560 QRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDL 1381
+ L ++ E++ A R AKL +NSA+LQF WK DVVESWI EKE ++++D+GRDL
Sbjct: 1996 AKMAALGEKVAELDRAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDL 2055
Query: 1380 SSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNL 1201
SSVQ LLTKQE FDAGL AF+ EGI I+ LK+QL++++H Q+ AI+ RH +I+RW L
Sbjct: 2056 SSVQTLLTKQETFDAGLQAFQQEGISNISALKEQLLAAQHVQAKAIQARHAALIKRWTQL 2115
Query: 1200 LAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRA 1021
L++S AR+ ++E+L+L FAKKAS FNSWFENAEEDLTDPVRCNSLEEIRA
Sbjct: 2116 LSNSAARKKKLLEAQEHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEIRA 2175
Query: 1020 LRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKE 841
LR+AH F+ SLSSA+ DF QL +LD++IKS+ V NPYTWFTM+ALE+TWRNLQ+IIKE
Sbjct: 2176 LREAHEAFRSSLSSAQADFDQLAELDKQIKSYLVVSNPYTWFTMEALEETWRNLQKIIKE 2235
Query: 840 REQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQE--------------------- 724
RE EL +E +RQEENDKLR+EFA+ ANAFH WL TR
Sbjct: 2236 RELELQKEQRRQEENDKLRQEFAQHANAFHQWLQETRTYLLDGFLGLLGPGPGAVTHLSV 2295
Query: 723 ------MMEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERNLILDNRYTEHST 562
M+E GTLE QL+A +RK +EI+A + QL++IE+ GA +E LILDN+YTEHST
Sbjct: 2296 CVGRSCMVEESGTLESQLEATKRKHQEIRAMRSQLKKIEDLGAAMEEALILDNKYTEHST 2355
Query: 561 VGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMMFKHFDKEKTGRLDHQQ 382
VG+AQ WDQLDQL MRMQHNLEQQIQARN +GV+EEAL+EFSMMFKHFDKEK+GRL+HQ+
Sbjct: 2356 VGLAQQWDQLDQLGMRMQHNLEQQIQARNTTGVTEEALKEFSMMFKHFDKEKSGRLNHQE 2415
Query: 381 FKSCLRALGYDLPMVDEGQPEPEFQRILDIVDPNRD 274
FKSCLR+LGYDLPMV+EG+P+PEFQ ILD VDPNR+
Sbjct: 2416 FKSCLRSLGYDLPMVEEGEPDPEFQAILDTVDPNRE 2451
Score = 419 bits (1078), Expect = e-115
Identities = 422/1952 (21%), Positives = 800/1952 (40%), Gaps = 229/1952 (11%)
Frame = -1
Query: 5970 SAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAET 5791
+ G K++E + ++Q++ +++ L RR E Q F RD E+ E
Sbjct: 3 TTGVKVLET----AEDIQDRRQQVLDRYRRFKELSVMRRQKLEDSYRFQCFRRDAEELEK 58
Query: 5790 WMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAA 5611
W+ ++ ++ + D +++ ++KH+ FE + A I LDE +I H+A+
Sbjct: 59 WIQEKLQIASDENYKDP-SNLQGKLQKHQAFEAEVQANAGTIIKLDETGNLMISEGHFAS 117
Query: 5610 DDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSY 5431
+ + +G L ++ K + R+C++ + WI++K + A +
Sbjct: 118 ETIRSRLEELHRLWDLLLQKTKEKGLRLLQAQKLVQYLRECEDALDWISDKEAMATSEEL 177
Query: 5430 -LDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLW 5254
D ++ +K F+ +L A+E R++++ ++I H + I + +VN W
Sbjct: 178 GQDLEHVELLQKKFEEFQTDLAAHEERVNEVNQLAAKLIQESHPEVELIVRKQDEVNAAW 237
Query: 5253 NELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKI 5074
L ++ +L A Q+FNR++++ +W+ E E +AS+D+G+DL SVQ L +K
Sbjct: 238 QRLKGLAQQRQGRLFGAAEVQRFNRDVDETISWIKEKEQLMASDDFGRDLASVQALLRKH 297
Query: 5073 GLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKL 4894
+E D A D+V+ + A + QE NA I+ K++ L + +R +R +L
Sbjct: 298 EGLERDLAALEDKVNTLGGDAGRLQETHPQNASQILLKKDELVANWEQIRTLAAERHARL 357
Query: 4893 GESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQI 4714
+S++ + D D +W+ E + + + D+ G + L+ + Q EI H+
Sbjct: 358 DDSYRLQRFTADFRDLTSWVTEMQALIKADELANDVAGAEALLDRHQEHKGEIDAHEDSF 417
Query: 4713 ESVSSAANDMIQQGHFLAPEIRDK----------------------------LAQLRDNW 4618
S A ++ GH+ + E+++K L L +
Sbjct: 418 RSTDEAGQALVNTGHYASEEVKEKVGLPPDCPQTAGVVFSCVSRVCVCVRVQLGILSEEK 477
Query: 4617 RILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKH 4438
L + E RR + + + D + D WMS++E + + D G DS EALLKKH
Sbjct: 478 EALLNLWEVRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEALLKKH 537
Query: 4437 RALLSDLEAFKGTIEDLRKQAS---QCKYQEQPMGQLGRDCVLALYD--YQEKSPREVSM 4273
L A + I L + A+ Q + + RD +L+ + ++ R ++
Sbjct: 538 EDFEKSLSAQEEKITALDEFATKLIQNNHYAKEDVATRRDALLSRRNALHERAQSRRAAL 597
Query: 4272 KKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIE--PGTAQQH----AQQQVNS--I 4117
+ L + D K +N++ K G Q+H A+ N I
Sbjct: 598 EDSFHLQQF-FRDSDELKSWINEKMKTATDEAYKDPSNLQGKVQKHQAFEAELSANQSRI 656
Query: 4116 GGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIG-- 3943
Q +D +R R++EE ++ L EA +L + + + A A QQE G
Sbjct: 657 DALQKSGQDLLERKHYASSEVARRMEEVSSQWKKLLEATEL-KASRGQPAAAVQQERGGH 715
Query: 3942 ------------------------TDLEQVEVLQKKFDDFKGDLKANEV-----RLQEMN 3850
E+ + G L+ N + R+ ++
Sbjct: 716 RAVAVRGGGPPGLRRLRQGPDQRPEPAEEARAAGGRRGCSPGLLRVNSLISSQDRIDGIS 775
Query: 3849 QIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETR 3670
A G + A IR++ E L R+ AL +L + +Q+ RDV++
Sbjct: 776 IQARQFQEAGHFD-ADNIRRKQEALALRYEALRQPMATRKQKLSDSLRLQQLFRDVEDEE 834
Query: 3669 DWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEA 3490
WI+EK+ S + G+DL VQ L +KH+ ++ ++ +IK++ +K + + A
Sbjct: 835 TWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIVGHEPRIKAVTQKGETMVEEGHFA 894
Query: 3489 AEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQE 3310
E + EL+ +W+ L KA+ RK+ L DS Q++ +D + W+ +V S +
Sbjct: 895 GEDVKVKLTELHGRWDTLKLKASQRKQDLEDSLQAQQYFADANEAESWMREKEPIVGSTD 954
Query: 3309 LANDVTGAEALLERHQEYRTEIDSRAATFQAF---------------DQFGNQLLNSHH- 3178
D AEALL++H+ +++ + ++ Q D+ G +L+ + +
Sbjct: 955 YGKDEDSAEALLKKHEALMSDLSAYGSSIQGLKEQAQSCRQQVAPTDDETGKELVLALYD 1014
Query: 3177 ----------YAAGDIENRLQGVNEARKGLEDAWVA-------RRNILDQCLELQLFYRD 3049
GDI L N+ + L + A R ++ L
Sbjct: 1015 YQEKSPREVTMKKGDILTLLNSTNKVERWLACSRAAGSAPPWWRLQVVGLAEPSSLHPMT 1074
Query: 3048 C--EQADTW---MSARE-----AFLAQEDPS-GDNVESLIKKHEDFDKAINTQEEKIKGL 2902
C D W ++ R+ A++ + DP+ + E+L+++H +I ++++I+
Sbjct: 1075 CGLSWQDWWKVEVNDRQGFVPAAYVKKLDPNQSSSRENLLEEH----GSIALRQDQIENQ 1130
Query: 2901 KLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIE 2722
+ E+ +V+ + Q+ + + L E +++ L +S R+A+E++
Sbjct: 1131 LVTKEAC---------SVSVRMKQVEELYANLLELGEKRKDMLEKSCKKFMLFREANELQ 1181
Query: 2721 NWMTEK-FQIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCG 2545
W+ EK + EE D ++ +K F+ +L AN R+ I + L
Sbjct: 1182 QWIHEKEGTLTNEEVGSDLEQVEVLQKKFDDFQKDLKANESRLRDINKVAAELESEGLMA 1241
Query: 2544 GGEAAVSARLKA----------------------LNDQWDL------------------- 2488
V A++ L Q +L
Sbjct: 1242 EETPMVQAQVPGVPPGARLAFRRQHQPHPLFFLFLQQQQELLGAAPGKDEADSKTASPWK 1301
Query: 2487 ---LVKTTTEKSYRLKEAN----------KQKSFM--AAVKDLE---FWLGEVEILLQSE 2362
L TT +KE N + +S M +A +D + W+ E L ++
Sbjct: 1302 NVRLAVQTTANFNTIKELNNRWRSLQQLAEDRSHMLGSATRDADETKEWIEEKNQALNTD 1361
Query: 2361 DYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIAD 2182
+YG DLASV+ L +KH E D+ A D+V + E A+ L+++ + I E+ +
Sbjct: 1362 NYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAERLIQSHPEAVEDIKEKCSELNT 1421
Query: 2181 RYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRR 2002
+ + A R+DKL+ + ++ +F D D SWI + LVSS++ +D+ G + L
Sbjct: 1422 AWSSLVGRADQRKDKLANSHDLQRFLSDFRDLMSWINGIRGLVSSEELAKDVTGAEALLE 1481
Query: 2001 KHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGN 1822
+H+ TE+ + + G++LL +I++++E LEQ +
Sbjct: 1482 RHQEHRTEIDARAGTFQAFEQFGQQLL---VRGHYASPEIQQKLEALEQERTHLEKAWVQ 1538
Query: 1821 RHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLEL 1642
R LD+ Q F D E+ E WM ++ L SD+ G+++ V+ L+KKH+ F + +
Sbjct: 1539 RRMMLDQCLELQLFSRDCEQAENWMAAREAFLASDDKGDSLDSVEALIKKHEDFDKAINV 1598
Query: 1641 HKQRVADLINKGDTLIHNGNHHAPHIKQRCDQL--RARLIEI------------------ 1522
++++A L + D LI ++ I RC ++ RA + I
Sbjct: 1599 QEEKIAALQSFADQLIGADHYAKAEIHSRCREVLDRASIRSIRRSRQSCTLTQTHPRGHR 1658
Query: 1521 --------------ESMAEGRLA------------------KLRDNSAYLQFMWKCDVVE 1438
E + RLA KL++ + F +
Sbjct: 1659 HGNALIQRGACAGSEDAVKTRLAALDEQWQFLVNKSAEKSQKLKEANKQQNFNTGIKDFD 1718
Query: 1437 SWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQ 1258
W++E E + SED+G+DL+SV LL K + +A ++A E + ++ + D L++S+
Sbjct: 1719 FWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHE-DRLKDLNSQADSLMASDAF 1777
Query: 1257 QSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFEN 1078
+ ++ + + V R+ + + + RR +L SW +
Sbjct: 1778 DTSQVKDKRSGVNARFAKIKSMAATRRARLNESHRLHQFFRDL--------DDEESWIKE 1829
Query: 1077 AEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTW 898
+ ++ L ++ LR H + L + E + + D +++ N
Sbjct: 1830 KKLLVSSEDYGRDLTGVQNLRKKHKRLEAELGAHEPAIQSVLDTGKKLSDDNTIGQEEIQ 1889
Query: 897 FTMDALEDTWRNLQRIIKEREQELAREHQRQE 802
+ D W+ L+ + R Q L + Q+
Sbjct: 1890 QRLAQFVDHWKELKDLSGARGQRLEESLEYQQ 1921
Score = 291 bits (746), Expect = 1e-76
Identities = 230/1012 (22%), Positives = 435/1012 (42%), Gaps = 51/1012 (5%)
Frame = -1
Query: 3831 TSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEK 3652
T V ETA I+ + + + R+R +L ++ Q F RD +E WIQEK
Sbjct: 4 TGVKVLETAEDIQDRRQQVLDRYRRFKELSVMRRQKLEDSYRFQCFRRDAEELEKWIQEK 63
Query: 3651 DDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYD 3472
E++ +D ++Q +KH+ E ++ A I LDE N + A+E I
Sbjct: 64 LQIASDENY-KDPSNLQGKLQKHQAFEAEVQANAGTIIKLDETGNLMISEGHFASETIRS 122
Query: 3471 LQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVT 3292
EL+ W+ L K + +LL + ++L + D + WI+ + +S+EL D+
Sbjct: 123 RLEELHRLWDLLLQKTKEKGLRLLQAQKLVQYLRECEDALDWISDKEAMATSEELGQDLE 182
Query: 3291 GAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLED 3112
E L ++ +E++T++ + +Q +L+ H I + VN A + L+
Sbjct: 183 HVELLQKKFEEFQTDLAAHEERVNEVNQLAAKLIQESHPEVELIVRKQDEVNAAWQRLKG 242
Query: 3111 AWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGD--NVESLIKKHEDFDK 2938
R+ L E+Q F RD ++ +W+ +E +A +D D +V++L++KHE ++
Sbjct: 243 LAQQRQGRLFGAAEVQRFNRDVDETISWIKEKEQLMASDDFGRDLASVQALLRKHEGLER 302
Query: 2937 AINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQT 2758
+ E+K+ L A L + + ++ + K+D+++ W ++ ++ +L +S
Sbjct: 303 DLAALEDKVNTLGGDAGRLQETHPQNASQILLKKDELVANWEQIRTLAAERHARLDDSYR 362
Query: 2757 LQQFSRDADEIENWMTE-KFQIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQ 2581
LQ+F+ D ++ +W+TE + I +E D + + Q + E+ A+ D + +
Sbjct: 363 LQRFTADFRDLTSWVTEMQALIKADELANDVAGAEALLDRHQEHKGEIDAHEDSFRSTDE 422
Query: 2580 AGNNLIENAKCGGGE--------------------------AAVSARLKALNDQWDLLVK 2479
AG L+ E V +L L+++ + L+
Sbjct: 423 AGQALVNTGHYASEEVKEKVGLPPDCPQTAGVVFSCVSRVCVCVRVQLGILSEEKEALLN 482
Query: 2478 TTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEA 2299
+ + ++ + F + ++ W+ + E L +ED G L SVE LLKKH E
Sbjct: 483 LWEVRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEALLKKHEDFEK 542
Query: 2298 DIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALN 2119
+ A ++++ ++E A L++N+ + + +A RR + R + + + A RR L + +
Sbjct: 543 SLSAQEEKITALDEFATKLIQNNHYAKEDVATRRDALLSRRNALHERAQSRRAALEDSFH 602
Query: 2118 VHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKL 1939
+ QFFRD D+ +SWI E K+ ++D+ +D +Q +KH+ + EL++++ ++ ++
Sbjct: 603 LQQFFRDSDELKSWINE-KMKTATDEAYKDPSNLQGKVQKHQAFEAELSANQSRIDALQK 661
Query: 1938 KGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLG----- 1774
G++LL A ++ +RME++ W ++ + T + R + A Q G
Sbjct: 662 SGQDLLERKHYA---SSEVARRMEEVSSQWKKLLEATELKASRGQPAAAVQQERGGHRAV 718
Query: 1773 -----------------DVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLE 1645
D E A E + G + V L+ D
Sbjct: 719 AVRGGGPPGLRRLRQGPDQRPEPA--EEARAAGGRRGCSPGLLRVNSLISSQD------- 769
Query: 1644 LHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQ 1465
R+ + + G+ A +I+++ + L R + R KL D+ Q
Sbjct: 770 ----RIDGISIQARQFQEAGHFDADNIRRKQEALALRYEALRQPMATRKQKLSDSLRLQQ 825
Query: 1464 FMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELK 1285
+ E+WI EKE S + G+DL VQ LL K +A A + E I+ +T+
Sbjct: 826 LFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIVGHEPR-IKAVTQKG 884
Query: 1284 DQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKA 1105
+ +V H ++ + T + RW L + R+ + Y A A +A
Sbjct: 885 ETMVEEGHFAGEDVKVKLTELHGRWDTLKLKASQRKQDLEDSLQA-----QQYFADANEA 939
Query: 1104 STFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQD 949
SW E + + AL H LS+ + L++
Sbjct: 940 ---ESWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQGLKE 988
Score = 44.3 bits (103), Expect(2) = 0.0
Identities = 26/72 (36%), Positives = 37/72 (51%)
Frame = -3
Query: 286 PEQRWLRNSARVHGVHDQQRNREHPVFGRNRDGIQSSFEGIPTICHGRGALREPDTGASR 107
P + R A VHG+HDQ R+ E V +R+ + + GA+ EPD GA R
Sbjct: 2448 PNRERERVPAGVHGLHDQPRDGERQVQRGDRERLPGPERREQALRDQGGAVPEPDQGAGR 2507
Query: 106 ILHTKNEAIHGR 71
+L +EA+ GR
Sbjct: 2508 LLPVPHEALPGR 2519
>gi|1174412|sp|P02549|SPCA_HUMAN Spectrin alpha chain, erythrocyte
(Erythroid alpha-spectrin)
Length = 2418
Score = 2004 bits (5192), Expect = 0.0
Identities = 1046/2417 (43%), Positives = 1542/2417 (63%), Gaps = 15/2417 (0%)
Frame = -1
Query: 7215 RILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQT 7036
++LETA++I +RRQEVL Y FK+ + +LE++ Q FKRDAD+L WI+EK+
Sbjct: 16 KVLETAEEIQERRQEVLTRYQSFKERVAERGQKLEDSYHLQVFKRDADDLGKWIMEKVNI 75
Query: 7035 AQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEE 6856
++++ DP+N+Q K QKH++ EAEVQ ++ ++ L+KT H A E K +EE
Sbjct: 76 LTDKSYEDPTNIQGKYQKHQSLEAEVQTKSRLMSELEKTREERFTMGHSAHEETKAHIEE 135
Query: 6855 LHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEI 6676
L LW KG +L +ALK ++++C +IL WI +KE T+ ++G D E E+
Sbjct: 136 LRHLWDLLLELTLEKGDQLLRALKFQQYVQECADILEWIGDKEAIATSVELGEDWERTEV 195
Query: 6675 LQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAAT 6496
L +KF+DF EL + R+ E+NQ A++ EE H + I K+++VN AW RL LA
Sbjct: 196 LHKKFEDFQVELVAKEGRVVEVNQYANECAEENHPDLPLIQSKQNEVNAAWERLRGLALQ 255
Query: 6495 RKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAA 6316
R++ L A +QRF RD E + WI EK+ L+S+DYG+DL + L H+G ER+LA
Sbjct: 256 RQKALSNAANLQRFKRDVTEAIQWIKEKEPVLTSEDYGKDLVASEGLFHSHKGLERNLAV 315
Query: 6315 LEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRF 6136
+ K+ +L +A KL +HP A I + +D ++W ++ A R + L+ ++ HRF
Sbjct: 316 MSDKVKELCAKAEKLTLSHPSDAPQIQEMKEDLVSSWEHIRALATSRYEKLQATYWYHRF 375
Query: 6135 LADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQK 5956
+D+ +L W+ + A I ADEL DVAG E LL+ HQ+HK EID+ D F GQ
Sbjct: 376 SSDFDELSGWMNEKTAAINADELPTDVAGGEVLLDRHQQHKHEIDSYDDRFQSADETGQD 435
Query: 5955 LVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQ 5776
LV S EV+EK+E LD+ ++LL LW+ER YEQC+D LFYRD+EQ ++WM++Q
Sbjct: 436 LVNANHEASDEVREKMEILDNNWTALLELWDERHRQYEQCLDFHLFYRDSEQVDSWMSRQ 495
Query: 5775 EAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAE 5596
EAFL N DLG+SL S E L++KHEDFE++ AQEEKI +D+ ATKLI HY ++++
Sbjct: 496 EAFLENEDLGNSLGSAEALLQKHEDFEEAFTAQEEKIITVDKTATKLIGDDHYDSENIKA 555
Query: 5595 XXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTN 5416
R LKES Q D D++ +WI +K A D+ Y D N
Sbjct: 556 IRDGLLARRDALREKAATRRRLLKESLLLQKLYEDSDDLKNWINKKKKLADDEDYKDIQN 615
Query: 5415 IRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDA 5236
++ ++QK FE+EL N+ +L++I+ TG+++I+ GH+A+D++ RL +V +LW EL++A
Sbjct: 616 LKSRVQKQQVFEKELAVNKTQLENIQKTGQEMIEGGHYASDNVTTRLSEVASLWEELLEA 675
Query: 5235 TNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESD 5056
T +KG +L EA + QF N ED++ WL ++E QV SEDYGK L VQN +K GL+ES
Sbjct: 676 TKQKGTQLHEANQQLQFENNAEDLQRWLEDVEWQVTSEDYGKGLAEVQNRLRKHGLLESA 735
Query: 5055 FNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQG 4876
A D+VD + LA F+E H ++ I +QE+L R+ AL++PL RK+KL +
Sbjct: 736 VAARQDQVDILTDLAAYFEEIGHPDSKDIRARQESLVCRFEALKEPLATRKKKLLDLLHL 795
Query: 4875 NQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSA 4696
+ RD EDE AWI+E E A ST G+DLI + L+ + + ++ IA+H+ +I+ ++
Sbjct: 796 QLICRDTEDEEAWIQETEPSATSTYLGKDLIASKKLLNRHRVILENIASHEPRIQEITER 855
Query: 4695 ANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWM 4516
N M+++GHF A ++ ++ L N L+++A +R+ DL+ ++Q QYL+D +EA+ W+
Sbjct: 856 GNKMVEEGHFAAEDVASRVKSLNQNMESLRARAARRQNDLEANVQFQQYLADLHEAETWI 915
Query: 4515 SEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQP--MG 4342
EKEPIV +T+YG DE++A ALLKKH A L DL +F +++ LR QA+ C+ Q+ G
Sbjct: 916 REKEPIVDNTNYGADEEAAGALLKKHEAFLLDLNSFGDSMKALRNQANACQQQQAAPVEG 975
Query: 4341 QLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRI- 4165
G V+ALYD+Q +SPREV+MKKGDVLTLL++ N+DWWKVE D QG VPA YV+R+
Sbjct: 976 VAGEQRVMALYDFQARSPREVTMKKGDVLTLLSSINKDWWKVEAADHQGIVPAVYVRRLA 1035
Query: 4164 --EPGTAQQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLA 3991
E Q +++ +I +Q +IE++Y+ L+ E R+R+L + + L EA D+
Sbjct: 1036 HDEFPMLPQRRREEPGNITQRQEQIENQYRSLLDRAEERRRRLLQRYNEFLLAYEAGDML 1095
Query: 3990 EWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVG-QT 3814
EWI+ ++A + G +L+ V LQKKFD+F+ DL NE RL+++N++A L G T
Sbjct: 1096 EWIQEKKA----ENTGVELDDVWELQKKFDEFQKDLNTNEPRLRDINKVADDLLFEGLLT 1151
Query: 3813 ETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDS 3634
+IRQ +LNARW +L LGSAH V+ FHR+ D+T++ I++K AL +
Sbjct: 1152 PEGAQIRQ---ELNARWGSLQRLADEQRQLLGSAHAVEVFHREADDTKEQIEKKCQALSA 1208
Query: 3633 EDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELN 3454
D G DL SVQALQR+HEG ERDL LGDK+ L E A RL +SHP+A E + + ELN
Sbjct: 1209 ADPGSDLFSVQALQRRHEGFERDLVPLGDKVTILGETAERLSESHPDATEDLQRQKMELN 1268
Query: 3453 EQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALL 3274
E W L + +RKE L ++ + FLS RDL WI+S+ +VSSQELA D+TG E LL
Sbjct: 1269 EAWEDLQGRTKDRKESLNEAQKFYLFLSKARDLQNWISSIGGMVSSQELAEDLTGIEILL 1328
Query: 3273 ERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARR 3094
ERHQE+R ++++ A TFQA + F +L++S H+A+ +IE +LQ V R LE AW R+
Sbjct: 1329 ERHQEHRADMEAEAPTFQALEDFSAELIDSGHHASPEIEKKLQAVKLERDDLEKAWEKRK 1388
Query: 3093 NILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSG-DNVESLIKKHEDFDKAINTQEE 2917
ILDQCLELQ+F +C+Q ++ M ARE L +D S D++E+L+KK +D DKAI QE
Sbjct: 1389 KILDQCLELQMFQGNCDQVESRMVARENSLRSDDKSSLDSLEALMKKRDDLDKAITAQEG 1448
Query: 2916 KIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRD 2737
KI L+ FAESLI + HY + + ++LDRW LK LI +R KLG+ L+QF RD
Sbjct: 1449 KITDLEHFAESLIADEHYAKEEIATRLQRVLDRWKALKAQLIDERTKLGDYANLKQFYRD 1508
Query: 2736 ADEIENWMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIEN 2557
+E+E W++E A +E+Y+D TNIQ+K+ K Q F E+ S+++ +I GN+LIE
Sbjct: 1509 LEELEEWISEMLPTACDESYKDATNIQRKYLKHQTFAHEVDGRSEQVHGVINLGNSLIER 1568
Query: 2556 AKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEI 2377
+ C G E A+ +L+ L + WD L++ T +K +L EA++Q+ F +++D EFWL E E
Sbjct: 1569 S-CDGNEEAMKEQLEQLKEHWDHLLERTNDKGKKLNEASRQQRFNTSIRDFEFWLSEAET 1627
Query: 2376 LLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERR 2197
LL +D +DLAS NLLKKH LLE +++A +D + ++N A+ LL + F QI +++
Sbjct: 1628 LLAMKDQARDLASAGNLLKKHQLLEREMLAREDALKDLNTLAEDLLSSGTFNVDQIVKKK 1687
Query: 2196 KLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGV 2017
+ R+ V+++A +KL +A + QFF+D+DDEESWI+EK + VSS DYGRDL GV
Sbjct: 1688 DNVNKRFLNVQELAAAHHEKLKEAYALFQFFQDLDDEESWIEEKLIRVSSQDYGRDLQGV 1747
Query: 2016 QNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIR 1837
QNL +KH+R++ EL +HEP + V E+L AA VG+++I+ R+ + W +++
Sbjct: 1748 QNLLKKHKRLEGELVAHEPAIQNVLDMAEKLKDKAA---VGQEEIQLRLAQFVEHWEKLK 1804
Query: 1836 DLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQ 1657
+L R +L+ES + F+ + EEEEAW+NEK + + G+ +A Q LL KH+ +
Sbjct: 1805 ELAKARGLKLEESLEYLQFMQNAEEEEAWINEKNALAVRGDCGDTLAATQSLLMKHEALE 1864
Query: 1656 VDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLA---KLR 1486
D +H+ RV ++ +G+ +++ H K+ ++ A + S+A+ A +L
Sbjct: 1865 NDFAVHETRVQNVCAQGEDILNKVLHEESQNKEISSKIEALNEKTPSLAKAIAAWKLQLE 1924
Query: 1485 DNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGI 1306
D+ A+ +F WK DVVE+WIA+KE +++ G DL LL KQ+ DA L +F+ E +
Sbjct: 1925 DDYAFQEFNWKADVVEAWIADKETSLKTNGNGADLGDFLTLLAKQDTLDASLQSFQQERL 1984
Query: 1305 QRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELY 1126
IT+LKD+L+S++H QS AIE+R+ +++RW+ LL S R + E+L+
Sbjct: 1985 PEITDLKDKLISAQHNQSKAIEERYAALLKRWEQLLEASAVHRQKLLEKQLPLQKAEDLF 2044
Query: 1125 LAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDL 946
+ FA KAS N+W E EE+L++PV C SL EIR L+ H +F SL+ A+ DF+ L +L
Sbjct: 2045 VEFAHKASALNNWCEKMEENLSEPVHCVSLNEIRQLQKDHEDFLASLARAQADFKCLLEL 2104
Query: 945 DRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKL 766
D++IK+ V +PYTW T++ LE TW++L II+EREQEL +E RQ +N ++ +EF +
Sbjct: 2105 DQQIKALGVPSSPYTWLTVEVLERTWKHLSDIIEEREQELQKEEARQVKNFEMCQEFEQN 2164
Query: 765 ANAFHAWLTNTRQ-----EMMEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLER 601
A+ F W+ TR +++ GTLE QL+A +RK KEI+A K QL +I + G LE
Sbjct: 2165 ASTFLQWILETRAYFLDGSLLKETGTLESQLEANKRKQKEIQAMKRQLTKIVDLGDNLED 2224
Query: 600 NLILDNRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMMFKH 421
LILD +Y ST+G+AQ WDQL QL +RMQHNLEQQIQA++ GVSEE L+EFS ++KH
Sbjct: 2225 ALILDIKY---STIGLAQQWDQLYQLGLRMQHNLEQQIQAKDIKGVSEETLKEFSTIYKH 2281
Query: 420 FDKEKTGRLDHQQFKSCLRALGYDLPMVDEGQPEPEFQRILDIVDPNRDGYVTLQEYMAF 241
FD+ TGRL H++F+SCLR L Y LPMV+E + EP+F++ LD VDP R GYV+L++Y AF
Sbjct: 2282 FDENLTGRLTHKEFRSCLRGLNYYLPMVEEDEHEPKFEKFLDAVDPGRKGYVSLEDYTAF 2341
Query: 240 MISKETENIQSSEEIEMAFRALSKEFRPYVTAEELYANLTPEQAEFCIRRMKPYMDAISG 61
+I KE+ENI+SS+EIE AF+AL+ E + Y+T E++ LTPEQ FC M+ YMD
Sbjct: 2342 LIDKESENIKSSDEIENAFQALA-EGKSYITKEDMKQALTPEQVSFCATHMQQYMDP-RV 2399
Query: 60 RSIQGGLDYEQFVHALF 10
+I +DY F ++ F
Sbjct: 2400 EAISLAMDYVGFTNSYF 2416
Score = 119 bits (298), Expect = 1e-24
Identities = 104/499 (20%), Positives = 212/499 (41%), Gaps = 2/499 (0%)
Frame = -1
Query: 2319 KHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRD 2140
K +++E+ + E+ E+ +L Q +++AER + + D Y
Sbjct: 6 KETVVESSGPKVLETAEEIQERRQEVLTRYQSFKERVAERGQKLEDSY------------ 53
Query: 2139 KLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEP 1960
++ F RD DD WI EK +++ Y D +Q +KH+ ++ E+ +
Sbjct: 54 ------HLQVFKRDADDLGKWIMEKVNILTDKSY-EDPTNIQGKYQKHQSLEAEVQTKSR 106
Query: 1959 QVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAF 1780
+S ++ EE A ++ K +E+L W + +LT + +L + FQ +
Sbjct: 107 LMSELEKTREERFTMGHSA---HEETKAHIEELRHLWDLLLELTLEKGDQLLRALKFQQY 163
Query: 1779 LGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDT 1600
+ + + W+ +K+ I S GE+ + L KK + FQV+L + RV ++ +
Sbjct: 164 VQECADILEWIGDKEAIATSVELGEDWERTEVLHKKFEDFQVELVAKEGRVVEVNQYANE 223
Query: 1599 LIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVES--WIA 1426
+ P I+ + +++ A + +A R K N+A LQ +K DV E+ WI
Sbjct: 224 CAEENHPDLPLIQSKQNEVNAAWERLRGLALQR-QKALSNAANLQ-RFKRDVTEAIQWIK 281
Query: 1425 EKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPA 1246
EKE + SED+G+DL + + L + + L A + ++ + ++L S +P
Sbjct: 282 EKEPVLTSEDYGKDLVASEGLFHSHKGLERNL-AVMSDKVKELCAKAEKLTLSHPSDAPQ 340
Query: 1245 IEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEED 1066
I++ +++ W+++ A + +R Y F+ + W
Sbjct: 341 IQEMKEDLVSSWEHIRALATSRYEKLQATY--------WYHRFSSDFDELSGWMNEKTAA 392
Query: 1065 LTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMD 886
+ + L D H + + + S ++ F+ + + + + N + M+
Sbjct: 393 INADELPTDVAGGEVLLDRHQQHKHEIDSYDDRFQSADETGQDLVNANHEASDEVREKME 452
Query: 885 ALEDTWRNLQRIIKEREQE 829
L++ W L + ER ++
Sbjct: 453 ILDNNWTALLELWDERHRQ 471
>gi|4507189|ref|NP_003117.1| spectrin, alpha, erythrocytic 1
(elliptocytosis 2); Spectrin, alpha, erythrocytic-1 [Homo
sapiens]
gi|71566|pir||SJHUA spectrin alpha chain - human
gi|338438|gb|AAA60577.1| erythroid alpha spectrin
gi|460309|gb|AAA60994.1| alpha-spectrin
Length = 2429
Score = 2001 bits (5184), Expect = 0.0
Identities = 1041/2396 (43%), Positives = 1533/2396 (63%), Gaps = 15/2396 (0%)
Frame = -1
Query: 7215 RILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQT 7036
++LETA++I +RRQEVL Y FK+ + +LE++ Q FKRDAD+L WI+EK+
Sbjct: 16 KVLETAEEIQERRQEVLTRYQSFKERVAERGQKLEDSYHLQVFKRDADDLGKWIMEKVNI 75
Query: 7035 AQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEE 6856
++++ DP+N+Q K QKH++ EAEVQ ++ ++ L+KT H A E K +EE
Sbjct: 76 LTDKSYEDPTNIQGKYQKHQSLEAEVQTKSRLMSELEKTREERFTMGHSAHEETKAHIEE 135
Query: 6855 LHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEI 6676
L LW KG +L +ALK ++++C +IL WI +KE T+ ++G D E E+
Sbjct: 136 LRHLWDLLLELTLEKGDQLLRALKFQQYVQECADILEWIGDKEAIATSVELGEDWERTEV 195
Query: 6675 LQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAAT 6496
L +KF+DF EL + R+ E+NQ A++ EE H + I K+++VN AW RL LA
Sbjct: 196 LHKKFEDFQVELVAKEGRVVEVNQYANECAEENHPDLPLIQSKQNEVNAAWERLRGLALQ 255
Query: 6495 RKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAA 6316
R++ L A +QRF RD E + WI EK+ L+S+DYG+DL + L H+G ER+LA
Sbjct: 256 RQKALSNAANLQRFKRDVTEAIQWIKEKEPVLTSEDYGKDLVASEGLFHSHKGLERNLAV 315
Query: 6315 LEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRF 6136
+ K+ +L +A KL +HP A I + +D ++W ++ A R + L+ ++ HRF
Sbjct: 316 MSDKVKELCAKAEKLTLSHPSDAPQIQEMKEDLVSSWEHIRALATSRYEKLQATYWYHRF 375
Query: 6135 LADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQK 5956
+D+ +L W+ + A I ADEL DVAG E LL+ HQ+HK EID+ D F GQ
Sbjct: 376 SSDFDELSGWMNEKTAAINADELPTDVAGGEVLLDRHQQHKHEIDSYDDRFQSADETGQD 435
Query: 5955 LVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQ 5776
LV S EV+EK+E LD+ ++LL LW+ER YEQC+D LFYRD+EQ ++WM++Q
Sbjct: 436 LVNANHEASDEVREKMEILDNNWTALLELWDERHRQYEQCLDFHLFYRDSEQVDSWMSRQ 495
Query: 5775 EAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAE 5596
EAFL N DLG+SL S E L++KHEDFE++ AQEEKI +D+ ATKLI HY ++++
Sbjct: 496 EAFLENEDLGNSLGSAEALLQKHEDFEEAFTAQEEKIITVDKTATKLIGDDHYDSENIKA 555
Query: 5595 XXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTN 5416
R LKES Q D D++ +WI +K A D+ Y D N
Sbjct: 556 IRDGLLARRDALREKAATRRRLLKESLLLQKLYEDSDDLKNWINKKKKLADDEDYKDIQN 615
Query: 5415 IRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDA 5236
++ ++QK FE+EL N+ +L++I+ TG+++I+ GH+A+D++ RL +V +LW EL++A
Sbjct: 616 LKSRVQKQQVFEKELAVNKTQLENIQKTGQEMIEGGHYASDNVTTRLSEVASLWEELLEA 675
Query: 5235 TNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESD 5056
T +KG +L EA + QF N ED++ WL ++E QV SEDYGK L VQN +K GL+ES
Sbjct: 676 TKQKGTQLHEANQQLQFENNAEDLQRWLEDVEWQVTSEDYGKGLAEVQNRLRKHGLLESA 735
Query: 5055 FNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQG 4876
A D+VD + LA F+E H ++ I +QE+L R+ AL++PL RK+KL +
Sbjct: 736 VAARQDQVDILTDLAAYFEEIGHPDSKDIRARQESLVCRFEALKEPLATRKKKLLDLLHL 795
Query: 4875 NQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSA 4696
+ RD EDE AWI+E E A ST G+DLI + L+ + + ++ IA+H+ +I+ ++
Sbjct: 796 QLICRDTEDEEAWIQETEPSATSTYLGKDLIASKKLLNRHRVILENIASHEPRIQEITER 855
Query: 4695 ANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWM 4516
N M+++GHF A ++ ++ L N L+++A +R+ DL+ ++Q QYL+D +EA+ W+
Sbjct: 856 GNKMVEEGHFAAEDVASRVKSLNQNMESLRARAARRQNDLEANVQFQQYLADLHEAETWI 915
Query: 4515 SEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQP--MG 4342
EKEPIV +T+YG DE++A ALLKKH A L DL +F +++ LR QA+ C+ Q+ G
Sbjct: 916 REKEPIVDNTNYGADEEAAGALLKKHEAFLLDLNSFGDSMKALRNQANACQQQQAAPVEG 975
Query: 4341 QLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRI- 4165
G V+ALYD+Q +SPREV+MKKGDVLTLL++ N+DWWKVE D QG VPA YV+R+
Sbjct: 976 VAGEQRVMALYDFQARSPREVTMKKGDVLTLLSSINKDWWKVEAADHQGIVPAVYVRRLA 1035
Query: 4164 --EPGTAQQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLA 3991
E Q +++ +I +Q +IE++Y+ L+ E R+R+L + + L EA D+
Sbjct: 1036 HDEFPMLPQRRREEPGNITQRQEQIENQYRSLLDRAEERRRRLLQRYNEFLLAYEAGDML 1095
Query: 3990 EWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVG-QT 3814
EWI+ ++A + G +L+ V LQKKFD+F+ DL NE RL+++N++A L G T
Sbjct: 1096 EWIQEKKA----ENTGVELDDVWELQKKFDEFQKDLNTNEPRLRDINKVADDLLFEGLLT 1151
Query: 3813 ETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDS 3634
+IRQ +LNARW +L LGSAH V+ FHR+ D+T++ I++K AL +
Sbjct: 1152 PEGAQIRQ---ELNARWGSLQRLADEQRQLLGSAHAVEVFHREADDTKEQIEKKCQALSA 1208
Query: 3633 EDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELN 3454
D G DL SVQALQR+HEG ERDL LGDK+ L E A RL +SHP+A E + + ELN
Sbjct: 1209 ADPGSDLFSVQALQRRHEGFERDLVPLGDKVTILGETAERLSESHPDATEDLQRQKMELN 1268
Query: 3453 EQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALL 3274
E W L + +RKE L ++ + FLS RDL WI+S+ +VSSQELA D+TG E LL
Sbjct: 1269 EAWEDLQGRTKDRKESLNEAQKFYLFLSKARDLQNWISSIGGMVSSQELAEDLTGIEILL 1328
Query: 3273 ERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARR 3094
ERHQE+R ++++ A TFQA + F +L++S H+A+ +IE +LQ V R LE AW R+
Sbjct: 1329 ERHQEHRADMEAEAPTFQALEDFSAELIDSGHHASPEIEKKLQAVKLERDDLEKAWEKRK 1388
Query: 3093 NILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSG-DNVESLIKKHEDFDKAINTQEE 2917
ILDQCLELQ+F +C+Q ++ M ARE L +D S D++E+L+KK +D DKAI QE
Sbjct: 1389 KILDQCLELQMFQGNCDQVESRMVARENSLRSDDKSSLDSLEALMKKRDDLDKAITAQEG 1448
Query: 2916 KIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRD 2737
KI L+ FAESLI + HY + + ++LDRW LK LI +R KLG+ L+QF RD
Sbjct: 1449 KITDLEHFAESLIADEHYAKEEIATRLQRVLDRWKALKAQLIDERTKLGDYANLKQFYRD 1508
Query: 2736 ADEIENWMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIEN 2557
+E+E W++E A +E+Y+D TNIQ+K+ K Q F E+ S+++ +I GN+LIE
Sbjct: 1509 LEELEEWISEMLPTACDESYKDATNIQRKYLKHQTFAHEVDGRSEQVHGVINLGNSLIER 1568
Query: 2556 AKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEI 2377
+ C G E A+ +L+ L + WD L++ T +K +L EA++Q+ F +++D EFWL E E
Sbjct: 1569 S-CDGNEEAMKEQLEQLKEHWDHLLERTNDKGKKLNEASRQQRFNTSIRDFEFWLSEAET 1627
Query: 2376 LLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERR 2197
LL +D +DLAS NLLKKH LLE +++A +D + ++N A+ LL + F QI +++
Sbjct: 1628 LLAMKDQARDLASAGNLLKKHQLLEREMLAREDALKDLNTLAEDLLSSGTFNVDQIVKKK 1687
Query: 2196 KLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGV 2017
+ R+ V+++A +KL +A + QFF+D+DDEESWI+EK + VSS DYGRDL GV
Sbjct: 1688 DNVNKRFLNVQELAAAHHEKLKEAYALFQFFQDLDDEESWIEEKLIRVSSQDYGRDLQGV 1747
Query: 2016 QNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIR 1837
QNL +KH+R++ EL +HEP + V E+L AA VG+++I+ R+ + W +++
Sbjct: 1748 QNLLKKHKRLEGELVAHEPAIQNVLDMAEKLKDKAA---VGQEEIQLRLAQFVEHWEKLK 1804
Query: 1836 DLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQ 1657
+L R +L+ES + F+ + EEEEAW+NEK + + G+ +A Q LL KH+ +
Sbjct: 1805 ELAKARGLKLEESLEYLQFMQNAEEEEAWINEKNALAVRGDCGDTLAATQSLLMKHEALE 1864
Query: 1656 VDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLA---KLR 1486
D +H+ RV ++ +G+ +++ H K+ ++ A + S+A+ A +L
Sbjct: 1865 NDFAVHETRVQNVCAQGEDILNKVLHEESQNKEISSKIEALNEKTPSLAKAIAAWKLQLE 1924
Query: 1485 DNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGI 1306
D+ A+ +F WK DVVE+WIA+KE +++ G DL LL KQ+ DA L +F+ E +
Sbjct: 1925 DDYAFQEFNWKADVVEAWIADKETSLKTNGNGADLGDFLTLLAKQDTLDASLQSFQQERL 1984
Query: 1305 QRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELY 1126
IT+LKD+L+S++H QS AIE+R+ +++RW+ LL S R + E+L+
Sbjct: 1985 PEITDLKDKLISAQHNQSKAIEERYAALLKRWEQLLEASAVHRQKLLEKQLPLQKAEDLF 2044
Query: 1125 LAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDL 946
+ FA KAS N+W E EE+L++PV C SL EIR L+ H +F SL+ A+ DF+ L +L
Sbjct: 2045 VEFAHKASALNNWCEKMEENLSEPVHCVSLNEIRQLQKDHEDFLASLARAQADFKCLLEL 2104
Query: 945 DRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKL 766
D++IK+ V +PYTW T++ LE TW++L II+EREQEL +E RQ +N ++ +EF +
Sbjct: 2105 DQQIKALGVPSSPYTWLTVEVLERTWKHLSDIIEEREQELQKEEARQVKNFEMCQEFEQN 2164
Query: 765 ANAFHAWLTNTRQ-----EMMEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLER 601
A+ F W+ TR +++ GTLE QL+A +RK KEI+A K QL +I + G LE
Sbjct: 2165 ASTFLQWILETRAYFLDGSLLKETGTLESQLEANKRKQKEIQAMKRQLTKIVDLGDNLED 2224
Query: 600 NLILDNRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMMFKH 421
LILD +Y ST+G+AQ WDQL QL +RMQHNLEQQIQA++ GVSEE L+EFS ++KH
Sbjct: 2225 ALILDIKY---STIGLAQQWDQLYQLGLRMQHNLEQQIQAKDIKGVSEETLKEFSTIYKH 2281
Query: 420 FDKEKTGRLDHQQFKSCLRALGYDLPMVDEGQPEPEFQRILDIVDPNRDGYVTLQEYMAF 241
FD+ TGRL H++F+SCLR L Y LPMV+E + EP+F++ LD VDP R GYV+L++Y AF
Sbjct: 2282 FDENLTGRLTHKEFRSCLRGLNYYLPMVEEDEHEPKFEKFLDAVDPGRKGYVSLEDYTAF 2341
Query: 240 MISKETENIQSSEEIEMAFRALSKEFRPYVTAEELYANLTPEQAEFCIRRMKPYMD 73
+I KE+ENI+SS+EIE AF+AL+ E + Y+T E++ LTPEQ FC M+ YMD
Sbjct: 2342 LIDKESENIKSSDEIENAFQALA-EGKSYITKEDMKQALTPEQVSFCATHMQQYMD 2396
Score = 119 bits (298), Expect = 1e-24
Identities = 104/499 (20%), Positives = 212/499 (41%), Gaps = 2/499 (0%)
Frame = -1
Query: 2319 KHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRD 2140
K +++E+ + E+ E+ +L Q +++AER + + D Y
Sbjct: 6 KETVVESSGPKVLETAEEIQERRQEVLTRYQSFKERVAERGQKLEDSY------------ 53
Query: 2139 KLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEP 1960
++ F RD DD WI EK +++ Y D +Q +KH+ ++ E+ +
Sbjct: 54 ------HLQVFKRDADDLGKWIMEKVNILTDKSY-EDPTNIQGKYQKHQSLEAEVQTKSR 106
Query: 1959 QVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAF 1780
+S ++ EE A ++ K +E+L W + +LT + +L + FQ +
Sbjct: 107 LMSELEKTREERFTMGHSA---HEETKAHIEELRHLWDLLLELTLEKGDQLLRALKFQQY 163
Query: 1779 LGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDT 1600
+ + + W+ +K+ I S GE+ + L KK + FQV+L + RV ++ +
Sbjct: 164 VQECADILEWIGDKEAIATSVELGEDWERTEVLHKKFEDFQVELVAKEGRVVEVNQYANE 223
Query: 1599 LIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVES--WIA 1426
+ P I+ + +++ A + +A R K N+A LQ +K DV E+ WI
Sbjct: 224 CAEENHPDLPLIQSKQNEVNAAWERLRGLALQR-QKALSNAANLQ-RFKRDVTEAIQWIK 281
Query: 1425 EKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPA 1246
EKE + SED+G+DL + + L + + L A + ++ + ++L S +P
Sbjct: 282 EKEPVLTSEDYGKDLVASEGLFHSHKGLERNL-AVMSDKVKELCAKAEKLTLSHPSDAPQ 340
Query: 1245 IEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEED 1066
I++ +++ W+++ A + +R Y F+ + W
Sbjct: 341 IQEMKEDLVSSWEHIRALATSRYEKLQATY--------WYHRFSSDFDELSGWMNEKTAA 392
Query: 1065 LTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMD 886
+ + L D H + + + S ++ F+ + + + + N + M+
Sbjct: 393 INADELPTDVAGGEVLLDRHQQHKHEIDSYDDRFQSADETGQDLVNANHEASDEVREKME 452
Query: 885 ALEDTWRNLQRIIKEREQE 829
L++ W L + ER ++
Sbjct: 453 ILDNNWTALLELWDERHRQ 471
>gi|19526481|ref|NP_035595.2| spectrin alpha 1; alpha-spectrin 1,
erythroid; spherocytosis; hemolytic anemia [Mus musculus]
gi|3668418|gb|AAC61874.1| erythroid alpha-spectrin [Mus musculus]
Length = 2415
Score = 1996 bits (5171), Expect = 0.0
Identities = 1040/2415 (43%), Positives = 1538/2415 (63%), Gaps = 13/2415 (0%)
Frame = -1
Query: 7215 RILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQT 7036
++LETA++I RR EVL Y FKD + +LEE+ +Q F+RDAD+L WI+EKL+
Sbjct: 15 KVLETAEEIQHRRAEVLNQYQRFKDRVAERGQKLEESYHYQVFRRDADDLEKWIMEKLEI 74
Query: 7035 AQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEE 6856
A+++ + +P+N+Q K QKHE+F +EVQA ++ + L++ A +HFA E K L++
Sbjct: 75 AKDKTY-EPTNIQGKYQKHESFVSEVQAKSRVLPELEEIREARFAEDHFAHEATKTHLKQ 133
Query: 6855 LHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEI 6676
L LW K L +ALK + ++C++IL W++EKE VT ++G D E E+
Sbjct: 134 LRLLWDLLLELTQEKSDVLLRALKFYQYSQECEDILEWVKEKEAIVTLVELGDDWERTEV 193
Query: 6675 LQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAAT 6496
L +KF++F +EL + +++ +NQ A++ +E H + +I K+D+VN AW RL +LA
Sbjct: 194 LHKKFEEFQEELTARKGKVDRVNQYANECAQEKHPKLPEIKAKQDEVNAAWDRLWSLALK 253
Query: 6495 RKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAA 6316
R+E L A +QRF RD +E + W+ EK+ L+S+DYG+DL + +AL H+ ER+LA
Sbjct: 254 RRESLSNAADLQRFKRDVNEAIQWMEEKEPQLTSEDYGKDLVSSEALFHNHKRLERNLAV 313
Query: 6315 LEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRF 6136
++ K+ +L +A KL +H A I Q D + W ++ A +R L+ S+ HRF
Sbjct: 314 MDDKVKELCAKADKLMISHSADAPQIQQMKLDLVSNWERIRALATNRYAKLKASYGYHRF 373
Query: 6135 LADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQK 5956
L+DY +L W+ + A+I ADEL DVA EALL HQ+HK EID+ D F + GQ+
Sbjct: 374 LSDYDELSGWMKEKTALINADELPTDVASGEALLARHQQHKHEIDSYDDRFQSADATGQE 433
Query: 5955 LVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQ 5776
L++ S E++EK+ L ++ ++LL LW++ + Y QC+D LFYRD+EQ ++WM++Q
Sbjct: 434 LLDGNHEASEEIREKMTILANDWAALLELWDKCQHQYRQCLDFHLFYRDSEQVDSWMSRQ 493
Query: 5775 EAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAE 5596
EAFL N DLG+S+ SVE L++KH+DFE++ AQEEKI LDE ATKLI HY ++++A
Sbjct: 494 EAFLENEDLGNSVGSVEALLQKHDDFEEAFTAQEEKIITLDETATKLIDNDHYDSENIAA 553
Query: 5595 XXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTN 5416
R L +S Q +D D++ +WI +K A DD Y D N
Sbjct: 554 IRDGLLARRDALRERAATRRKLLVDSQLLQQLYQDSDDLKTWINKKKKLADDDDYKDVQN 613
Query: 5415 IRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDA 5236
++ ++QK +FE+EL NE L+++ TG+++I+ GH+A++ + RL +V NLW EL++A
Sbjct: 614 LKSRVQKQQDFEEELAVNEIMLNNLEKTGQEMIEDGHYASEAVAARLSEVANLWKELLEA 673
Query: 5235 TNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESD 5056
T +KG +L EA QF N ED++ WL E+E QV SEDYGK L VQNL +K GL+ESD
Sbjct: 674 TAQKGTQLYEANQLLQFENNAEDLKRWLEEVEWQVTSEDYGKGLADVQNLLRKHGLLESD 733
Query: 5055 FNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQG 4876
A ++VD + +A F+E H ++ I +QE+L R+ AL++PL RK+KL + +
Sbjct: 734 VTARQNQVDTLTDMAAHFEEIGHPDSGDIRARQESLLSRFEALKEPLAIRKKKLIDLLKL 793
Query: 4875 NQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSA 4696
Q+ RD EDE AWI+E E A ST+ G+DL+ +NL+ + + ++A+IA+H+ +I+ ++
Sbjct: 794 QQICRDSEDEEAWIQETEPSAASTHLGKDLVAAKNLLNRHEVILADIASHEPRIQVITER 853
Query: 4695 ANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWM 4516
N M+++GHF A +I ++ L N L ++A +R DL ++Q QYL+D +EA+AW+
Sbjct: 854 GNKMVEEGHFAAEDIASRVESLNKNMESLHARAIRRENDLKANVQLQQYLADLHEAEAWI 913
Query: 4515 SEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQE-QPMGQ 4339
EKEPIV + +YG DE++A ALLKKH A L DL AF+ +I+ LR QA C+ Q+ P+ +
Sbjct: 914 KEKEPIVDNKNYGADEEAAGALLKKHEAFLVDLNAFENSIKALRDQAEVCQQQQAAPVDE 973
Query: 4338 LGRDC-VLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIE 4162
GR+ V+ALYD++ +S REVSMKK DVLTLL++ N+DWWKVE +D QGFVPA YV+++
Sbjct: 974 AGREARVIALYDFEARSRREVSMKKNDVLTLLSSINKDWWKVEADDHQGFVPAVYVRKLA 1033
Query: 4161 PGTA---QQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLA 3991
P QH Q++ +I Q ++E Y L+ E R+R+L + + L EA D+
Sbjct: 1034 PDELPGFPQHRQEEPVNIPQLQQQVETLYHSLLDRAEERRRRLLQRYNEFLLAYEAGDML 1093
Query: 3990 EWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALT-SVGQT 3814
EWI+ ++ + G +L+ V LQKKFD+F+ DLK+NE RL+++N++A L T
Sbjct: 1094 EWIQEKKT----ENTGVELDDVWELQKKFDEFQRDLKSNEPRLKDINKVADELLFEELLT 1149
Query: 3813 ETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDS 3634
IRQ +LN RW +L L SAH V+ FHR+ D+ ++ I +K AL++
Sbjct: 1150 PEGAHIRQ---ELNTRWNSLKRLADEQYQLLSSAHAVEMFHREADDVKEQIDKKCRALNA 1206
Query: 3633 EDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELN 3454
D G DL SVQALQR+HE ERD+ LG+K+ +L E A RL +SHP+A E + + ELN
Sbjct: 1207 ADPGSDLLSVQALQRQHEVFERDIIPLGEKVTTLGETAERLCESHPDATEDLQKQRTELN 1266
Query: 3453 EQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALL 3274
E W+ L ++RKE L +++ + FLS DL WI ++ ++SS ELA D+TG E LL
Sbjct: 1267 EAWDTLQGLTSDRKESLNEAHKFFLFLSKASDLENWIKTIGGVISSPELAEDLTGTEILL 1326
Query: 3273 ERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARR 3094
ERHQE+ +I TFQA + FG +L++S H +I+N LQ +N R LE +W R+
Sbjct: 1327 ERHQEHHDDIKREDPTFQALEDFGTELIDSGHRNRREIDNTLQNINSKRDNLEKSWENRK 1386
Query: 3093 NILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSG-DNVESLIKKHEDFDKAINTQEE 2917
+LDQCLELQLF C+Q ++WM ARE L +D +++++L+KK +D DKAI QE
Sbjct: 1387 KMLDQCLELQLFRGKCDQVESWMVARENSLRSDDRDHLNSLQALMKKRDDLDKAITAQEG 1446
Query: 2916 KIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRD 2737
KI L+ A LI N+HY + + ++LDRW LKE L+ + KLG+ L+QF RD
Sbjct: 1447 KISDLENVATRLIDNDHYAKEEIAARLQRVLDRWKALKEQLLTELGKLGDYADLKQFYRD 1506
Query: 2736 ADEIENWMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIEN 2557
+++E W+ E IA +E+Y+DPTNIQ+K+ K QAFE E++ ++++ +I GN+LIE
Sbjct: 1507 LEDLEEWINEMLPIACDESYKDPTNIQRKYLKHQAFENEVNGRAEQVDGVINLGNSLIER 1566
Query: 2556 AKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEI 2377
C G E + +L L + WD L++ TT+K +L EA++Q+ F +++D EFWL E E
Sbjct: 1567 RVCDGDEENMQEQLDKLKENWDYLLERTTDKGQKLNEASRQQRFNTSIRDFEFWLSEAEG 1626
Query: 2376 LLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERR 2197
LL +D +DL S NLLKKH LLEA+++A +D + ++N+ A L+ + F QI E+
Sbjct: 1627 LLAMKDQARDLTSAGNLLKKHQLLEAEMLAREDPLKDLNDLAQELISSGTFNIDQIEEKM 1686
Query: 2196 KLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGV 2017
+ +R++ V+ +A +KL + + QFF+D+DDEE+WI+EK L VSS DYGRDL V
Sbjct: 1687 NGVNERFENVQSLAAAHHEKLKETYALFQFFQDLDDEEAWIEEKLLRVSSQDYGRDLQSV 1746
Query: 2016 QNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIR 1837
QNL +KH+R++ EL +HEP V V L E LR +A VG+++I++R+ Q W +++
Sbjct: 1747 QNLLKKHKRLEGELVAHEPAVQNV-LDTAESLRD--KAAVGKEEIQERLAQFVQHWEKLK 1803
Query: 1836 DLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQ 1657
+L R L+ES + F+ + EEEEAW+ EK ++ + G+ +A Q LLKKH+ +
Sbjct: 1804 ELAKTRGVNLEESLEYLQFMENAEEEEAWLGEKCALVSRGDSGDTLAATQSLLKKHEALE 1863
Query: 1656 VDLELHKQRVADLINKGDTLIH-NGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDN 1480
D +HK RV D+ +G+ +++ + I + L + + ++L D
Sbjct: 1864 NDFAVHKNRVQDVCAQGEDILNKEETQNKDKISTKIQVLNEKTASLAKALAAWKSQLDDV 1923
Query: 1479 SAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQR 1300
A+ QF WK DVVESWI EKE ++++ G DL++ LL K + DA L +F+ E +
Sbjct: 1924 HAFQQFNWKADVVESWIGEKEASLKTKSNGADLTAFLTLLAKHDTLDASLQSFQQERLSE 1983
Query: 1299 ITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLA 1120
I ELKDQLV+ EH Q+ AIE++H +++ W+ LL S R + EEL++
Sbjct: 1984 IAELKDQLVAGEHSQAKAIEEQHAALLRHWEQLLEASRVHRQKLLEKQLPLQKAEELFME 2043
Query: 1119 FAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDR 940
FA KAS FN+W ENAEEDL++PV C SL EIR L+ H F SL+ A+EDF L +LD+
Sbjct: 2044 FAHKASAFNNWCENAEEDLSEPVHCVSLNEIRQLQKEHEAFLASLAGAQEDFNYLLELDK 2103
Query: 939 RIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLAN 760
+IK+ NV +PYTW T+D L W +L IIKEREQEL +E RQ +N ++ +EF + A+
Sbjct: 2104 QIKALNVPSSPYTWLTVDVLGRIWNHLPDIIKEREQELQKEEARQIKNFEMCQEFEQNAS 2163
Query: 759 AFHAWLTNTRQ-----EMMEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERNL 595
AF W+ TR +++ GTLE QL+A +RK KEI+A K L +IE+ G +E L
Sbjct: 2164 AFLQWIQETRAYFLDGSLLKETGTLESQLEANKRKQKEIQAMKRHLTKIEDLGDSMEEAL 2223
Query: 594 ILDNRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMMFKHFD 415
ILD +Y ST+G+AQ WDQL QL MRMQHNLEQQIQA++ GVSEE L+EFS +KHFD
Sbjct: 2224 ILDIKY---STIGLAQQWDQLHQLGMRMQHNLEQQIQAKDTIGVSEETLKEFSTTYKHFD 2280
Query: 414 KEKTGRLDHQQFKSCLRALGYDLPMVDEGQPEPEFQRILDIVDPNRDGYVTLQEYMAFMI 235
+ TGRL H++F+SCLR L Y LPMV+EG+PEP+F++ L+ VDP R GYV+L++Y +F+I
Sbjct: 2281 ENLTGRLTHKEFRSCLRGLNYYLPMVEEGEPEPKFEKFLNAVDPGRKGYVSLEDYTSFLI 2340
Query: 234 SKETENIQSSEEIEMAFRALSKEFRPYVTAEELYANLTPEQAEFCIRRMKPYMDAISGRS 55
KE+ENI++S++IE AF+AL+ E + Y+T E++ LTPEQ FC M+ YMD GRS
Sbjct: 2341 DKESENIKTSDDIESAFQALA-EGKAYITKEDMKQALTPEQVSFCTIHMQQYMDP-RGRS 2398
Query: 54 IQGGLDYEQFVHALF 10
G DY F ++ F
Sbjct: 2399 QPAGYDYVGFTNSFF 2413
>gi|17380523|sp|P08032|SPCA_MOUSE Spectrin alpha chain, erythrocyte
(Erythroid alpha-spectrin)
gi|1841857|gb|AAB47540.1| erythroid alpha-spectrin [Mus musculus]
Length = 2415
Score = 1993 bits (5164), Expect = 0.0
Identities = 1038/2415 (42%), Positives = 1538/2415 (62%), Gaps = 13/2415 (0%)
Frame = -1
Query: 7215 RILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQT 7036
++LETA++I RR EVL Y FKD + +LEE+ +Q F+RDAD+L WI+EKL+
Sbjct: 15 KVLETAEEIQHRRAEVLNQYQRFKDRVAERGQKLEESYHYQVFRRDADDLEKWIMEKLEI 74
Query: 7035 AQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEE 6856
A+++ + +P+N+Q K QKHE+F +EVQA ++ + L++ A +HFA E K L++
Sbjct: 75 AKDKTY-EPTNIQGKYQKHESFVSEVQAKSRVLPELEEIREARFAEDHFAHEATKTHLKQ 133
Query: 6855 LHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEI 6676
L LW K L +ALK + ++C++IL W++EKE VT ++G D E E+
Sbjct: 134 LRLLWDLLLELTQEKSDVLLRALKFYQYSQECEDILEWVKEKEAIVTLVELGDDWERTEV 193
Query: 6675 LQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAAT 6496
L +KF++F +EL + +++ +NQ A++ +E H + +I K+D+VN AW RL +LA
Sbjct: 194 LHKKFEEFQEELTARKGKVDRVNQYANECAQEKHPKLPEIKAKQDEVNAAWDRLWSLALK 253
Query: 6495 RKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAA 6316
R+E L A +QRF RD +E + W+ EK+ L+S+DYG+DL + +AL H+ ER+LA
Sbjct: 254 RRESLSNAADLQRFKRDVNEAIQWMEEKEPQLTSEDYGKDLVSSEALFHNHKRLERNLAV 313
Query: 6315 LEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRF 6136
++ K+ +L +A KL +H A I Q D + W ++ A +R L+ S+ HRF
Sbjct: 314 MDDKVKELCAKADKLMISHSADALQIQQMKLDLVSNWERIRALATNRYAKLKASYGYHRF 373
Query: 6135 LADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQK 5956
L+DY +L W+ + A+I ADEL DVA EALL HQ+HK EID+ D F + GQ+
Sbjct: 374 LSDYDELSGWMKEKTALINADELPTDVASGEALLARHQQHKHEIDSYDDRFQSADATGQE 433
Query: 5955 LVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQ 5776
L++ S E++EK+ L ++ ++LL LW++ + Y QC+D LFYRD+EQ ++WM++Q
Sbjct: 434 LLDGNHEASEEIREKMTILANDWAALLELWDKCQHQYRQCLDFHLFYRDSEQVDSWMSRQ 493
Query: 5775 EAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAE 5596
EAFL N DLG+S+ SVE L++KH+DFE++ AQEEKI LDE ATKLI HY ++++A
Sbjct: 494 EAFLENEDLGNSVGSVEALLQKHDDFEEAFTAQEEKIITLDETATKLIDNDHYDSENIAA 553
Query: 5595 XXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTN 5416
R L +S Q +D D++ +WI +K A DD Y D N
Sbjct: 554 IRDGLLARRDALRERAATRRKLLVDSQLLQQLYQDSDDLKTWINKKKKLADDDDYKDVQN 613
Query: 5415 IRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDA 5236
++ ++QK +FE+EL NE L+++ TG+++I+ GH+A++ + RL +V NLW EL++A
Sbjct: 614 LKSRVQKQQDFEEELAVNEIMLNNLEKTGQEMIEDGHYASEAVAARLSEVANLWKELLEA 673
Query: 5235 TNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESD 5056
T +KG +L EA QF N ED++ WL E+E QV SEDYGK L VQNL +K GL+ESD
Sbjct: 674 TAQKGTQLYEANQLLQFENNAEDLKRWLEEVEWQVTSEDYGKVLADVQNLLRKHGLLESD 733
Query: 5055 FNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQG 4876
A +++D + +A F+E H ++ I +QE+L R+ AL++PL RK+KL + +
Sbjct: 734 VTARQNQMDTLTDMAAHFEEIGHPDSGDIRARQESLLSRFEALKEPLAIRKKKLIDLLKL 793
Query: 4875 NQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSA 4696
Q+ RD EDE AWI+E E A ST+ G+DL+ +NL+ + + ++A+IA+H+ +I+ ++
Sbjct: 794 QQICRDSEDEEAWIQETEPSAASTHLGKDLVAAKNLLNRHEVILADIASHEPRIQVITER 853
Query: 4695 ANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWM 4516
N M+++GHF A +I ++ L N L ++A +R DL ++Q QYL+D +EA+AW+
Sbjct: 854 GNKMVEEGHFAAEDIASRVESLNKNMESLHARAIRRENDLKANVQLQQYLADLHEAEAWI 913
Query: 4515 SEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQE-QPMGQ 4339
EKEPIV + +YG DE++A ALLKKH A L DL AF+ +I+ LR QA C+ Q+ P+ +
Sbjct: 914 KEKEPIVDNKNYGADEEAAGALLKKHEAFLVDLNAFENSIKALRDQAEVCQQQQAAPVDE 973
Query: 4338 LGRDC-VLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIE 4162
GR+ V+ALYD++ +S REVSMKK DVLTLL++ N+DWWKVE +D QGFVPA YV+++
Sbjct: 974 AGREARVIALYDFEARSRREVSMKKNDVLTLLSSINKDWWKVEADDHQGFVPAVYVRKLA 1033
Query: 4161 PGTA---QQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLA 3991
P QH +++ +I Q ++E Y L+ E R+R+L + + L EA D+
Sbjct: 1034 PDELPGFPQHQREEPVNIPQLQQQVETLYHSLLDRAEERRRRLLQRYNEFLLAYEAGDML 1093
Query: 3990 EWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALT-SVGQT 3814
EWI+ ++ + G +L+ V LQKKFD+F+ DLK+NE RL+++N++A L T
Sbjct: 1094 EWIQEKKT----ENTGVELDDVWELQKKFDEFQRDLKSNEPRLKDINKVADELLFEELLT 1149
Query: 3813 ETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDS 3634
IRQ +LN RW +L L SAH V+ FHR+ D+ ++ I +K AL++
Sbjct: 1150 PEGAHIRQ---ELNTRWNSLKRLADEQYQLLSSAHAVEMFHREADDVKEQIDKKCRALNA 1206
Query: 3633 EDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELN 3454
D G DL SVQALQR+HE ERD+ LG+K+ +L E A RL +SHP+A E + + ELN
Sbjct: 1207 ADPGSDLLSVQALQRQHECFERDIIPLGEKVNTLGETAERLCESHPDATEDLQKQRTELN 1266
Query: 3453 EQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALL 3274
E W+ L ++RKE L +++ + FLS DL WI ++ ++SS ELA D+TG E LL
Sbjct: 1267 EAWDTLQGLTSDRKESLNEAHKFFLFLSKASDLENWIKTIGGVISSPELAEDLTGTEILL 1326
Query: 3273 ERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARR 3094
ERHQE+ +I TFQA + FG +L++S H +I+N LQ +N R LE +W R+
Sbjct: 1327 ERHQEHHDDIKREDPTFQALEDFGTELIDSGHRNRREIDNTLQNINSKRDNLEKSWENRK 1386
Query: 3093 NILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSG-DNVESLIKKHEDFDKAINTQEE 2917
+LDQCLELQLF C+Q ++WM ARE L +D D++++L+KK +D DKAI QE
Sbjct: 1387 KMLDQCLELQLFRGKCDQVESWMVARENSLRSDDRDHLDSLQALMKKRDDLDKAITAQEG 1446
Query: 2916 KIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRD 2737
KI L+ A LI N+HY + + ++LDRW LKE L+ + KLG+ L+QF RD
Sbjct: 1447 KISDLENVATRLIDNDHYAKEEIAARLQRVLDRWKALKEQLLTELGKLGDYADLKQFYRD 1506
Query: 2736 ADEIENWMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIEN 2557
+++E W+ E IA +E+Y+DPTNIQ+K+ K QAFE E++ ++++ +I GN+LIE
Sbjct: 1507 LEDLEEWINEMLPIACDESYKDPTNIQRKYLKHQAFENEVNGRAEQVDGVINLGNSLIER 1566
Query: 2556 AKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEI 2377
C G E + +L L + WD L++ TT+K +L EA++Q+ F +++D EFWL E E
Sbjct: 1567 RVCDGDEENMQEQLDMLKENWDYLLERTTDKGQKLNEASRQQRFNTSIRDFEFWLSEAEG 1626
Query: 2376 LLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERR 2197
LL +D +DL S NLLKKH LLEA+++A +D + ++N+ A L+ + F QI E+
Sbjct: 1627 LLAMKDQARDLTSAGNLLKKHQLLEAEMLAREDPLKDLNDLAQELISSGTFNIDQIEEKM 1686
Query: 2196 KLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGV 2017
+ +R++ V+ +A +KL + + QFF+D+DDEE+WI+EK L VSS DYGRDL V
Sbjct: 1687 NGVNERFENVQSLAAAHHEKLKETYALFQFFQDLDDEEAWIEEKLLRVSSQDYGRDLQSV 1746
Query: 2016 QNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIR 1837
QNL +KH+R++ EL +HEP V V L E LR +A VG+++I++R+ Q W +++
Sbjct: 1747 QNLLKKHKRLEGELVAHEPAVQNV-LDTAESLRD--KAAVGKEEIQERLAQFVQHWEKLK 1803
Query: 1836 DLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQ 1657
+L R L+ES + F+ + EEEEAW+ EK ++ + G+ +A Q LLKKH+ +
Sbjct: 1804 ELAKTRGVNLEESLEYLQFMENAEEEEAWLGEKCALVSRGDSGDTLAATQSLLKKHEALE 1863
Query: 1656 VDLELHKQRVADLINKGDTLIH-NGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDN 1480
D +HK RV D+ +G+ +++ + I + L + + ++L D
Sbjct: 1864 NDFAVHKNRVQDVCAQGEDILNKEETQNKDKISTKIQVLNEKTASLAKALAAWKSQLDDV 1923
Query: 1479 SAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQR 1300
A+ QF WK DVVESWI EKE ++++ G DL++ LL K + DA L +F+ E +
Sbjct: 1924 HAFQQFNWKADVVESWIGEKEASLKTKSNGADLTAFLTLLAKHDTLDASLQSFQQERLSE 1983
Query: 1299 ITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLA 1120
I ELKDQLV+ EH Q+ AIE++H +++ W+ LL S R + EEL++
Sbjct: 1984 IAELKDQLVAGEHSQAKAIEEQHAALLRHWEQLLEASRVHRQKLLEKQLPLQKAEELFME 2043
Query: 1119 FAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDR 940
FA KAS FN+W ENAEED+++PV C SL EIR L+ H F SL+ A+EDF L +LD+
Sbjct: 2044 FAHKASAFNNWCENAEEDMSEPVHCVSLNEIRQLQKEHEAFLASLAGAQEDFNYLLELDK 2103
Query: 939 RIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLAN 760
+IK+ NV +PYTW T+D L W +L IIKEREQEL +E RQ +N ++ +EF + A+
Sbjct: 2104 QIKALNVPSSPYTWLTVDVLGRIWNHLPDIIKEREQELQKEEARQIKNFEMCQEFEQNAS 2163
Query: 759 AFHAWLTNTRQ-----EMMEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERNL 595
AF W+ TR +++ GTLE QL+A +RK KEI+A K L +IE+ G +E L
Sbjct: 2164 AFLQWIQETRAYFLDGSLLKETGTLESQLEANKRKQKEIQAMKRHLTKIEDLGDSMEEAL 2223
Query: 594 ILDNRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMMFKHFD 415
ILD +Y ST+G+AQ WDQL QL MRMQHNLEQQIQA++ GVSEE L+EFS +KHFD
Sbjct: 2224 ILDIKY---STIGLAQQWDQLHQLGMRMQHNLEQQIQAKDTIGVSEETLKEFSTTYKHFD 2280
Query: 414 KEKTGRLDHQQFKSCLRALGYDLPMVDEGQPEPEFQRILDIVDPNRDGYVTLQEYMAFMI 235
+ TGRL H++F+SCLR L Y LPMV+EG+PEP+F++ L+ VDP R GYV+L++Y +F+I
Sbjct: 2281 ENLTGRLTHKEFRSCLRGLNYYLPMVEEGEPEPKFEKFLNAVDPGRKGYVSLEDYTSFLI 2340
Query: 234 SKETENIQSSEEIEMAFRALSKEFRPYVTAEELYANLTPEQAEFCIRRMKPYMDAISGRS 55
KE+ENI++S++IE AF+AL+ E + Y+T E++ LTPEQ FC M+ YMD GRS
Sbjct: 2341 DKESENIKTSDDIESAFQALA-EGKAYITKEDMKQALTPEQVSFCTIHMQQYMDP-RGRS 2398
Query: 54 IQGGLDYEQFVHALF 10
G DY F ++ F
Sbjct: 2399 QPAGYDYVGFTNSFF 2413
>gi|33303718|gb|AAQ02378.1| erythroid spectrin alpha [Rattus
norvegicus]
Length = 2385
Score = 1919 bits (4972), Expect = 0.0
Identities = 1018/2412 (42%), Positives = 1503/2412 (62%), Gaps = 10/2412 (0%)
Frame = -1
Query: 7215 RILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQT 7036
++LETA++I RRQEVL Y FK+ + +LEE+ +Q F+RDAD+L WI+EKL+
Sbjct: 15 KVLETAEEIQHRRQEVLDQYQRFKERVAERGQKLEESYHYQVFRRDADDLEKWIMEKLEI 74
Query: 7035 AQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEE 6856
+++ + +P+N+Q K QKHE+F +EVQA ++ + L++ A +HFA E K L+E
Sbjct: 75 TKDKTY-EPTNIQGKYQKHESFVSEVQAKSRVLPELEEIREARFAEDHFAHEATKTHLKE 133
Query: 6855 LHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEI 6676
L LW K L +ALK + ++C++IL W++EKE VT ++G D E E+
Sbjct: 134 LRHLWDLLLELTQEKSDILLRALKFYQYCQECEDILEWVKEKEAIVTLVELGDDWERTEV 193
Query: 6675 LQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAAT 6496
L +KF++F +EL + +++ +NQ A++ +E H + +I K+D+VN AW RL +LA
Sbjct: 194 LHKKFEEFQEELTARKGKVDRVNQYANECAQEQHPKLPEIKAKQDEVNAAWDRLWSLALK 253
Query: 6495 RKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAA 6316
R+E L A +QRF RD +E + W+ EK+ L+S+DYG+DL + +AL H+ ER+LA
Sbjct: 254 RRESLSNAADLQRFKRDVNEAIQWMEEKEPLLTSEDYGKDLVSSEALFHSHKRLERNLAV 313
Query: 6315 LEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRF 6136
++ K+ +L +A KL +H A I Q D + W ++ A +R L+ S+ HRF
Sbjct: 314 MDDKVKELCAKADKLMVSHSADAPQIQQMKMDLVSNWELIRALATNRYAKLKASYGYHRF 373
Query: 6135 LADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQK 5956
L+DY +L W+ + A+I ADEL DVA EALL HQ+HK EID+ D F + GQ
Sbjct: 374 LSDYDELTGWMEEKTALINADELPTDVASGEALLARHQQHKHEIDSYDDRFQTAEATGQD 433
Query: 5955 LVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQ 5776
L++ S E++EK+ L H+ ++L LW + + Y Q +D LFYRD+EQ ++WM++Q
Sbjct: 434 LLDGNHEASDEIREKMTILAHDWAALRELWNKCQHQYRQSLDFHLFYRDSEQVDSWMSRQ 493
Query: 5775 EAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAE 5596
EAFL N DLG+S+ SVE L++KH+DFE++ AQEEKI LDE ATKLI HY ++++A
Sbjct: 494 EAFLENEDLGNSVGSVEALLQKHDDFEEAFTAQEEKIITLDETATKLIDNDHYDSENIAA 553
Query: 5595 XXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTN 5416
R L +S Q +D D++ +WI +K A D+ Y D N
Sbjct: 554 IRDGLLARRDALRERAATRRKLLVDSQLLQQLYQDSDDLKTWINKKKKLADDEDYKDVQN 613
Query: 5415 IRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDA 5236
++ ++QK +FE+EL ANE L+++ TG+ +I++ H+A+D + R+ +V NLW EL++A
Sbjct: 614 LKSRVQKQQDFEEELAANEIMLNNLERTGQDMIENDHYASDAVAARMSEVANLWKELLEA 673
Query: 5235 TNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESD 5056
T +KG +L EA QF N ED++ WL E+E QVASEDYGK L VQNL +K GL+ES
Sbjct: 674 TAQKGTQLYEANQLLQFENNAEDLKRWLEEVERQVASEDYGKGLADVQNLLRKHGLLESA 733
Query: 5055 FNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQG 4876
A D+VD + +A F+E H ++ I +QE+L R+ AL++PL RK+KL + +
Sbjct: 734 VLARQDQVDTLTDMAAHFEEIGHPDSENICARQESLLSRFEALKEPLATRKKKLIDLLKL 793
Query: 4875 NQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSA 4696
Q+ RD EDE AWI+E E A ST+ G+DL+ +NL+ + + ++A+IA+H+ +I++++
Sbjct: 794 QQICRDSEDEEAWIQETEPSAASTHLGKDLVAAKNLLNRHEVILADIASHEPRIQTITER 853
Query: 4695 ANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWM 4516
N M+++GHF + +I ++ L N L+++A +R DL ++Q QYL+D +EA+AW+
Sbjct: 854 GNKMVEEGHFASEDIASRVESLNKNMESLRARAIRRENDLKANVQLQQYLADLHEAEAWI 913
Query: 4515 SEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQE-QPMGQ 4339
EKEPIV + +YG DE++A ALLKKH A L DL AF +I+ L QA C+ Q+ P+ +
Sbjct: 914 KEKEPIVDNKNYGADEEAAGALLKKHEAFLVDLNAFGNSIKALGDQAEACQQQQAAPVDE 973
Query: 4338 LGRDC-VLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIE 4162
GR+ V+ALYD++ +S REVSMKK DVLTLL++ N+DWWKVE +D QGFVPA YV+++
Sbjct: 974 AGREARVIALYDFEARSRREVSMKKNDVLTLLSSINKDWWKVEADDHQGFVPAVYVRKLA 1033
Query: 4161 ----PGTAQQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDL 3994
PG QQ ++ VN I Q +IE Y L+ E R+R+L + + L EA D+
Sbjct: 1034 HDELPGFPQQRREEPVN-IPQLQEQIETLYHSLLDRAEERRRRLLQRYNEFLLAYEAGDM 1092
Query: 3993 AEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVG-Q 3817
EWI+ ++ + G +L+ V LQKKFD+F+ DLK+NE RL+++N++A L
Sbjct: 1093 LEWIQEKKT----ENTGVELDDVWELQKKFDEFQRDLKSNEPRLKDINKVADELLFEDLL 1148
Query: 3816 TETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALD 3637
T IRQ +LN RW +L L SAH V+ F R+ D+ ++ I +K AL+
Sbjct: 1149 TPEGSHIRQ---ELNTRWSSLKRLADEQYQLLSSAHAVEMFLREADDVKEQIDKKCQALN 1205
Query: 3636 SEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQREL 3457
+ D G DL SVQALQR+HE ERD+ LG+K+ +L E A RL +SHP+A E + + EL
Sbjct: 1206 AADPGSDLLSVQALQRQHEVFERDIIPLGEKVTTLGETAERLCESHPDATEDLQKQRTEL 1265
Query: 3456 NEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEAL 3277
NE W+ L ++RKE L +++ + FLS DL WI ++ ++SS ELA D+TG E L
Sbjct: 1266 NEAWDTLQGLTSDRKESLNEAHKFFLFLSKASDLENWIKAIGGVISSPELAEDLTGTEIL 1325
Query: 3276 LERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVAR 3097
LERHQE+ +I TFQA + FG +L++ H + +IE LQ + R LE W R
Sbjct: 1326 LERHQEHYDDIKREDPTFQALEDFGRELIDRGHRNSHEIETTLQDIKLKRDDLEKNWENR 1385
Query: 3096 RNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSG-DNVESLIKKHEDFDKAINTQE 2920
+ +LDQCLELQLF CEQ ++WM ARE L +D +++++L+KK +D DKAI QE
Sbjct: 1386 KKMLDQCLELQLFRGKCEQVESWMVARENSLRSDDRDHLNSLQALMKKRDDLDKAIAAQE 1445
Query: 2919 EKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSR 2740
KI L+ A L+ N+HY + + ++LDRW LK L+ + KLG+ L+QF R
Sbjct: 1446 GKIADLENHATRLMDNDHYAKEEIAARLQRVLDRWKDLKTQLLAELGKLGDYADLKQFYR 1505
Query: 2739 DADEIENWMTEKFQIAQEENYRDPTNIQQ-KHQKQQAFEAELHANSDRIAAIIQAGNNLI 2563
D +++E W++E +A +E+Y+DPTNIQQ K+ K QAFE E++ ++++ +I G +LI
Sbjct: 1506 DLEDLEEWISEMLPVACDESYKDPTNIQQRKYLKHQAFENEVNGRAEQVEGVINLGKSLI 1565
Query: 2562 ENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEV 2383
E C G E + +L L + WD L++ TT+K +L EA++Q+ F +++D EFWL E
Sbjct: 1566 ERRVCDGDEENMQEQLDKLKENWDYLLERTTDKGQKLNEASRQQRFNTSIRDFEFWLSEA 1625
Query: 2382 EILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAE 2203
E LL +D +DL S NLLKKH LLEA+++A +D + ++N A L+ + F +QI E
Sbjct: 1626 EGLLAMKDQARDLTSAGNLLKKHQLLEAEMLAREDPLKDLNGLAKELISSGTFNIEQIEE 1685
Query: 2202 RRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLP 2023
+ + +R+ V+ +A +KL + + QFF+D+DDEE+WI+EK L VSS D GRDL
Sbjct: 1686 KMNGVNERFKNVQSLAAAHHEKLKETYALFQFFQDLDDEEAWIEEKLLRVSSQDCGRDLQ 1745
Query: 2022 GVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQ 1843
VQNL +KHRR++ EL +HEP V V E L AA VG+++I++R+ Q W +
Sbjct: 1746 SVQNLLKKHRRLEGELVAHEPAVQNVLDTAESLKDKAA---VGKEEIQERLAQFVQHWEK 1802
Query: 1842 IRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDT 1663
+++L R L+ES + F+ + EEEEAW+ EK ++ + G+ +A Q LLKKH+
Sbjct: 1803 LKELAKTRGVNLEESLQYLQFMENAEEEEAWLGEKDALVSRGDSGDTLAATQSLLKKHEA 1862
Query: 1662 FQVDLELHKQRVADLINKG-DTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLR 1486
+ D +HK RV D+ +G D L + I + + L + + ++L
Sbjct: 1863 LENDFAVHKNRVQDVCAQGEDILSKEETQNKDKISTKIEVLNEKTASLTKALAAWKSQLD 1922
Query: 1485 DNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGI 1306
+ A+ QF WK DVVESWI EKE ++++ G DL++ LL KQ+ DA L +F+ E +
Sbjct: 1923 EVHAFQQFNWKADVVESWIGEKEASLKTKSNGADLTAFLTLLAKQDTLDASLQSFQQERL 1982
Query: 1305 QRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELY 1126
IT+LKD+L+++EH QS AIE+RH +++RW+ LL R + EEL+
Sbjct: 1983 SEITDLKDELLAAEHSQSKAIEERHAALLRRWEQLLEACRVHRQKLLEKQLPLQKAEELF 2042
Query: 1125 LAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDL 946
+ FA KAS FN+W ENAEEDL++PV C SL EIR L+ H F S+ A+EDF L L
Sbjct: 2043 MEFAHKASAFNNWCENAEEDLSEPVHCVSLNEIRQLQKEHEAFLASMVGAQEDFNYLLAL 2102
Query: 945 DRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKL 766
D++IK+ NV +PYTW T+D L W++L IIKEREQEL +E RQ +N ++ +EF +
Sbjct: 2103 DQQIKALNVSSSPYTWLTVDVLGRIWKHLPEIIKEREQELQKEEARQIKNFEMCQEFEQN 2162
Query: 765 ANAFHAWLTNTRQEMMEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERNLILD 586
A+AF W+ TR ++ RK KEI+A K L +IE+ G +E LILD
Sbjct: 2163 ASAFLQWIQETRAYFLDG--------SVFSRKQKEIQAMKRHLTKIEDLGDSMEEALILD 2214
Query: 585 NRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMMFKHFDKEK 406
+Y ST+G+AQ WDQL QL MRMQHNLEQQIQA KHFD+
Sbjct: 2215 IKY---STIGLAQQWDQLHQLGMRMQHNLEQQIQA------------------KHFDENL 2253
Query: 405 TGRLDHQQFKSCLRALGYDLPMVDEGQPEPEFQRILDIVDPNRDGYVTLQEYMAFMISKE 226
TGRL H++F+SCLR L Y LPMV+EG+PEP+F++ L+ VDP R GYV+L++Y +F+I KE
Sbjct: 2254 TGRLTHKEFRSCLRGLNYYLPMVEEGEPEPKFEKFLNAVDPGRKGYVSLEDYTSFLIDKE 2313
Query: 225 TENIQSSEEIEMAFRALSKEFRPYVTAEELYANLTPEQAEFCIRRMKPYMDAISGRSIQG 46
+ENI++S++IE F+AL+ E + Y+T E++ LTPEQ FC M+ YMD GRS
Sbjct: 2314 SENIKTSDDIESGFQALA-EGKAYITKEDMKQALTPEQVSFCTIHMQQYMDP-RGRSQPA 2371
Query: 45 GLDYEQFVHALF 10
G DY F ++ F
Sbjct: 2372 GYDYVGFTNSFF 2383
>gi|34880958|ref|XP_222913.2| similar to erythroid alpha-spectrin
[Rattus norvegicus]
Length = 2417
Score = 1893 bits (4903), Expect = 0.0
Identities = 1017/2454 (41%), Positives = 1505/2454 (60%), Gaps = 52/2454 (2%)
Frame = -1
Query: 7215 RILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQT 7036
++LETA++I RRQEVL Y FK+ + +LEE+ +Q F+RDAD+L WI+EKL+
Sbjct: 12 KVLETAEEIQHRRQEVLDQYQRFKERVAERGQKLEESYHYQVFRRDADDLEKWIMEKLEI 71
Query: 7035 AQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEE 6856
+++ + +P+N+Q K QKHE+F +EVQA ++ + L++ A +HFA E K L+E
Sbjct: 72 TKDKTY-EPTNIQGKYQKHESFVSEVQAKSRVLPELEEIREARFAEDHFAHEATKTHLKE 130
Query: 6855 LHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEI 6676
L LW K L +ALK + ++C++IL W++EKE VT ++G D E E+
Sbjct: 131 LRHLWDLLLELTQEKSDILLRALKFYQYCQECEDILEWVKEKEAIVTLVELGDDWERTEV 190
Query: 6675 LQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAAT 6496
L +KF++F +EL + +++ +NQ A++ +E H + +I K+D+VN AW RL +LA
Sbjct: 191 LHKKFEEFQEELTARKGKVDRVNQYANECAQEQHPKLPEIKAKQDEVNAAWDRLWSLALK 250
Query: 6495 RKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAA 6316
R+E L A +QRF RD +E + W+ EK+ L+S+DYG+DL + +AL H+ ER+LA
Sbjct: 251 RRESLSNAADLQRFKRDVNEAIQWMEEKEPLLTSEDYGKDLVSSEALFHSHKRLERNLAV 310
Query: 6315 LEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRF 6136
++ K+ +L +A KL +H A I Q D + W ++ A +R L+ S+ HRF
Sbjct: 311 MDDKVKELCAKADKLMVSHSADAPQIQQMKMDLVSNWELIRALATNRYAKLKASYGYHRF 370
Query: 6135 LADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQK 5956
L+DY +L W+ + A+I ADEL DVA EALL HQ+HK EID+ D F + GQ
Sbjct: 371 LSDYDELTGWMEEKTALINADELPTDVASGEALLARHQQHKHEIDSYDDRFQTAEATGQD 430
Query: 5955 LVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQ 5776
L++ S E++EK+ L H+ ++L LW + + Y Q +D LFYRD+EQ ++WM++Q
Sbjct: 431 LLDGNHEASDEIREKMTILAHDWAALRELWNKCQHQYRQSLDFHLFYRDSEQVDSWMSRQ 490
Query: 5775 EAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAE 5596
EAFL N DLG+S+ SVE L++KH+DFE++ AQEEKI LDE ATKLI HY ++++A
Sbjct: 491 EAFLENEDLGNSVGSVEALLQKHDDFEEAFTAQEEKIITLDETATKLIDNDHYDSENIAA 550
Query: 5595 XXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSY----- 5431
R L +S Q +D D++ +WI +K A D+ Y
Sbjct: 551 IRDGLLARRDALRERAATRRKLLVDSQLLQQLYQDSDDLKTWINKKKKLADDEDYKNDFP 610
Query: 5430 ------LDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQ 5269
D N++ ++QK +FE+EL ANE L+++ TG+ +I++ H+A+D + R+ +
Sbjct: 611 DFPILSQDVQNLKSRVQKQQDFEEELAANEIMLNNLERTGQDMIENDHYASDAVAARMSE 670
Query: 5268 VNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQN 5089
V NLW EL++AT +KG +L EA QF N ED++ WL E+E QVASEDYGK L VQN
Sbjct: 671 VANLWKELLEATAQKGTQLYEANQLLQFENNAEDLKRWLEEVERQVASEDYGKGLADVQN 730
Query: 5088 LQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEK 4909
L +K GL+ES A D+VD + +A F+E H ++ I +QE+L R+ AL++PL
Sbjct: 731 LLRKHGLLESAVLARQDQVDTLTDMAAHFEEIGHPDSENICARQESLLSRFEALKEPLAT 790
Query: 4908 RKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIAN 4729
RK+KL + + Q+ RD EDE AWI+E E A ST+ G+DL+ +NL+ + + ++A+IA+
Sbjct: 791 RKKKLIDLLKLQQICRDSEDEEAWIQETEPSAASTHLGKDLVAAKNLLNRHEVILADIAS 850
Query: 4728 HDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQY 4549
H+ +I++++ N M+++GHF + +I ++ L N L+++A +R DL ++Q QY
Sbjct: 851 HEPRIQTITERGNKMVEEGHFASEDIASRVESLNKNMESLRARAIRRENDLKANVQLQQY 910
Query: 4548 LSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQ 4369
L+D +EA+AW+ EKEPIV + +YG DE++A ALLKKH A L DL AF +I+ L QA
Sbjct: 911 LADLHEAEAWIKEKEPIVDNKNYGADEEAAGALLKKHEAFLVDLNAFGNSIKALGDQAEA 970
Query: 4368 CKYQE-QPMGQLGRDC-VLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQG 4195
C+ Q+ P+ + GR+ V+ALYD++ +S REVSMKK DVLTLL++ N+DWWKVE +D QG
Sbjct: 971 CQQQQAAPVDEAGREARVIALYDFEARSRREVSMKKNDVLTLLSSINKDWWKVEADDHQG 1030
Query: 4194 FVPAAYVKRIE----PGTAQQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACK 4027
FVPA YV+++ PG QQ ++ VN I Q +IE Y L+ E R+R+L +
Sbjct: 1031 FVPAVYVRKLAHDELPGFPQQRREEPVN-IPQLQEQIETLYHSLLDRAEERRRRLLQRYN 1089
Query: 4026 GYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQ 3847
+ L EA D+ EWI+ ++ + G +L+ V LQKKFD+F+ DLK+NE RL+++N+
Sbjct: 1090 EFLLAYEAGDMLEWIQEKKT----ENTGVELDDVWELQKKFDEFQRDLKSNEPRLKDINK 1145
Query: 3846 IATALTSVG-QTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETR 3670
+A L T IRQ +LN RW +L L SAH V+ F R+ D+ +
Sbjct: 1146 VADELLFEDLLTPEGSHIRQ---ELNTRWSSLKRLADEQYQLLSSAHAVEMFLREADDVK 1202
Query: 3669 DWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEA 3490
+ I +K AL++ D G DL SVQALQR+HE ERD+ LG+K+ +L E A RL +SHP+A
Sbjct: 1203 EQIDKKCQALNAADPGSDLLSVQALQRQHEVFERDIIPLGEKVTTLGETAERLCESHPDA 1262
Query: 3489 AEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQE 3310
E + + ELNE W+ L ++RKE L +++ + FLS DL WI ++ ++SS E
Sbjct: 1263 TEDLQKQRTELNEAWDTLQGLTSDRKESLNEAHKFFLFLSKASDLENWIKAIGGVISSPE 1322
Query: 3309 LANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEA 3130
LA D+TG E LLERHQE+ +I TFQA + FG +L++ H + +IE LQ +
Sbjct: 1323 LAEDLTGTEILLERHQEHYDDIKREDPTFQALEDFGRELIDRGHRNSHEIETTLQDIKLK 1382
Query: 3129 RKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSG-DNVESLIKKH 2953
R LE W R+ +LDQCLELQLF CEQ ++WM ARE L +D +++++L+KK
Sbjct: 1383 RDDLEKNWENRKKMLDQCLELQLFRGKCEQVESWMVARENSLRSDDRDHLNSLQALMKKR 1442
Query: 2952 EDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKL 2773
+D DKAI QE KI L+ A L+ N+HY + + ++LDRW LK L+ + KL
Sbjct: 1443 DDLDKAIAAQEGKIADLENHATRLMDNDHYAKEEIAARLQRVLDRWKDLKTQLLAELGKL 1502
Query: 2772 GESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIA 2593
G+ L+QF RD +++E W++E + +K+ K QAFE E++ ++++
Sbjct: 1503 GDYADLKQFYRDLEDLEEWISEM--------------LPRKYLKHQAFENEVNGRAEQVE 1548
Query: 2592 AIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAV 2413
+I G +LIE C G E + +L L + WD L++ TT+K +L EA++Q+ F ++
Sbjct: 1549 GVINLGKSLIERRVCDGDEENMQEQLDKLKENWDYLLERTTDKGQKLNEASRQQRFNTSI 1608
Query: 2412 KDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLEN 2233
+D EFWL E E LL +D +DL S NLLKKH LLEA+++A +D + ++N A L+ +
Sbjct: 1609 RDFEFWLSEAEGLLAMKDQARDLTSAGNLLKKHQLLEAEMLAREDPLKDLNGLAKELISS 1668
Query: 2232 DQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLV 2053
F +QI E+ + +R+ V+ +A +KL + + QFF+D+DDEE+WI+EK L V
Sbjct: 1669 GTFNIEQIEEKMNGVNERFKNVQSLAAAHHEKLKETYALFQFFQDLDDEEAWIEEKLLRV 1728
Query: 2052 SSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKR 1873
SS D GRDL VQNL +KHRR++ EL +HEP V V E L AA VG+++I++R
Sbjct: 1729 SSQDCGRDLQSVQNLLKKHRRLEGELVAHEPAVQNVLDTAESLKDKAA---VGKEEIQER 1785
Query: 1872 MEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAG 1693
+ Q W ++++L R L+ES + F+ + EEEEAW+ EK ++ + G+ +A
Sbjct: 1786 LAQFVQHWEKLKELAKTRGVNLEESLQYLQFMENAEEEEAWLGEKDALVSRGDSGDTLAA 1845
Query: 1692 VQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHN---------GNH------------- 1579
Q LLKKH+ + D +HK RV D+ +G+ +++ GNH
Sbjct: 1846 TQSLLKKHEALENDFAVHKNRVQDVCAQGEDILNKKISSFLMVLGNHVSSSFAWLPNSSS 1905
Query: 1578 -----------HAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESW 1432
+ I + + L + + ++L + A+ QF WK DVVESW
Sbjct: 1906 HLTLASQEETQNKDKISTKIEVLNEKTASLTKALAAWKSQLDEVHAFQQFNWKADVVESW 1965
Query: 1431 IAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQS 1252
I EKE ++++ G DL++ LL KQ+ DA L +F+ E + IT+LKD+L+++EH QS
Sbjct: 1966 IGEKEASLKTKSNGADLTAFLTLLAKQDTLDASLQSFQQERLSEITDLKDELLAAEHSQS 2025
Query: 1251 PAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAE 1072
AIE+RH +++RW+ LL R + EEL++ FA KAS FN+W ENAE
Sbjct: 2026 KAIEERHAALLRRWEQLLEACRVHRQKLLEKQLPLQKAEELFMEFAHKASAFNNWCENAE 2085
Query: 1071 EDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFT 892
EDL++PV C SL EIR L+ H F S+ A+EDF L LD++IK+ NV +PYTW T
Sbjct: 2086 EDLSEPVHCVSLNEIRQLQKEHEAFLASMVGAQEDFNYLLALDQQIKALNVSSSPYTWLT 2145
Query: 891 MDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEMMEA 712
+D L W++L IIKEREQEL +E RQ +N ++ +EF + A+AF W+ TR + E
Sbjct: 2146 VDVLGRIWKHLPEIIKEREQELQKEEARQIKNFEMCQEFEQNASAFLQWIQETRSLLKET 2205
Query: 711 GGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERNLILDNRYTEHSTVGIAQAWDQL 532
GTLE QL+A +RK KEI+A K L +IE+ G +E LILD +Y ST+G+AQ WDQL
Sbjct: 2206 -GTLESQLEANKRKQKEIQAMKRHLTKIEDLGDSMEEALILDIKY---STIGLAQQWDQL 2261
Query: 531 DQLAMRMQHNLEQQIQARNQSGVSEEALREFSMMFKHFDKEKTGRLDHQQFKSCLRALGY 352
QL MRMQHNLEQQIQA KHFD+ TGRL H++F+SCLR L Y
Sbjct: 2262 HQLGMRMQHNLEQQIQA------------------KHFDENLTGRLTHKEFRSCLRGLNY 2303
Query: 351 DLPMVDEGQPEPEFQRILDIVDPNRDGYVTLQEYMAFMISKETENIQSSEEIEMAFRALS 172
LPMV+EG+PEP+F++ L+ VDP R GYV+L++Y +F+I KE+ENI++S++IE F+AL+
Sbjct: 2304 YLPMVEEGEPEPKFEKFLNAVDPGRKGYVSLEDYTSFLIDKESENIKTSDDIESGFQALA 2363
Query: 171 KEFRPYVTAEELYANLTPEQAEFCIRRMKPYMDAISGRSIQGGLDYEQFVHALF 10
E + Y+T E++ LTPEQ FC M+ YMD GRS G DY F ++ F
Sbjct: 2364 -EGKAYITKEDMKQALTPEQVSFCTIHMQQYMDP-RGRSQPAGYDYVGFTNSFF 2415
>gi|46577681|sp|P16546|SPCN_MOUSE Spectrin alpha chain, brain
(Spectrin, non-erythroid alpha chain) (Alpha-II spectrin)
(Fodrin alpha chain)
Length = 1458
Score = 1727 bits (4473), Expect = 0.0
Identities = 862/1459 (59%), Positives = 1090/1459 (74%), Gaps = 45/1459 (3%)
Frame = -1
Query: 4251 LLNASNRDWWKVEVNDRQGFVPAAYVKRIEPG--TAQQHAQQQVNSIGGKQSEIEDKYQR 4078
LLN++N+DWWKVEVNDRQGFVPAAYVK+++P ++++ ++ SI +Q +I+++YQ
Sbjct: 2 LLNSTNKDWWKVEVNDRQGFVPAAYVKKLDPAQSASRENLLEEQGSIALRQGQIDNQYQS 61
Query: 4077 LMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDD 3898
L+ LGE RK LE++CK + L REAN+L +WI +EA +E+G DLEQVEVLQKKFDD
Sbjct: 62 LLELGEKRKGMLEKSCKKFMLFREANELQQWITEKEAALTNEEVGADLEQVEVLQKKFDD 121
Query: 3897 FKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQ----------------------- 3787
F+ DLKANE RL+++N++A L S G V+ QQ
Sbjct: 122 FQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYGAMPRDEADSKTASPWKSA 181
Query: 3786 ------------IEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDA 3643
I++LN RWR+L LGSAHEVQRFHRD DET++WI+EK+ A
Sbjct: 182 RLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQA 241
Query: 3642 LDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQR 3463
L+++++G DL SVQALQRKHEG ERDLAALGDK+ SL E A RL QSHPE+AE + +
Sbjct: 242 LNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAQRLIQSHPESAEDLKEKCT 301
Query: 3462 ELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAE 3283
ELN+ W L +A+ RK KL DS+D QRFLSD+RDLM WI + LVSS ELA DVTGAE
Sbjct: 302 ELNQAWTSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAE 361
Query: 3282 ALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWV 3103
ALLERHQE+RTEID+RA TFQAF+QFG QLL HYA+ +I+ +L +++ R LE AWV
Sbjct: 362 ALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKEKLDILDQERTDLEKAWV 421
Query: 3102 ARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDP--SGDNVESLIKKHEDFDKAIN 2929
RR +LD CLELQLF+RDCEQA+ WM+AREAFL ED S D+VE+LIKKHEDFDKAIN
Sbjct: 422 QRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAIN 481
Query: 2928 TQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQ 2749
QEEKI L+ FA+ LI +HY + +R+++LDRW LK +I+KR KLGESQTLQQ
Sbjct: 482 VQEEKIAALQAFADQLIAVDHYAKGDIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQ 541
Query: 2748 FSRDADEIENWMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNN 2569
FSRD DEIE W++EK Q A +E+Y+DPTNIQ KHQK QAFEAELHAN+DRI +I GN+
Sbjct: 542 FSRDVDEIEAWISEKLQTASDESYKDPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNS 601
Query: 2568 LIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLG 2389
LIE C G E AV ARL AL DQW LV+ + EKS +LKEANKQ++F +KD +FWL
Sbjct: 602 LIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLS 661
Query: 2388 EVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQI 2209
EVE LL SEDYGKDLASV NLLKKH LLEADI AH+DR+ ++N QADSL+ + F Q+
Sbjct: 662 EVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQV 721
Query: 2208 AERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRD 2029
E+R I R+ +K MAT RR KLS++ +HQFFRD+DDEESWIKEKKLLVSS+DYGRD
Sbjct: 722 KEKRDTINGRFQKIKSMATSRRAKLSESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRD 781
Query: 2028 LPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSW 1849
L GVQNLR+KH+R++ ELA+HEP + V G++L + + +G+++I++R+ + W
Sbjct: 782 LTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKL---SDDNTIGQEEIQQRLAQFVEHW 838
Query: 1848 GQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKH 1669
+++ L R QRL+ES +Q F+ +VEEEEAW+NEK ++ S+++G+ +A +QGLLKKH
Sbjct: 839 KELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKH 898
Query: 1668 DTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKL 1489
+ F+ D +HK RV D+ G LI NHH +I + L ++ ++E A R AKL
Sbjct: 899 EAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKVSDLEKAAAQRKAKL 958
Query: 1488 RDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEG 1309
+NSA+LQF WK DVVESWI EKE ++++D+GRDLSSVQ LLTKQE FDAGL AF+ EG
Sbjct: 959 DENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEG 1018
Query: 1308 IQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEEL 1129
I IT LKDQL++++H QS AIE RH ++++RW LLA+S R+ ++E+L
Sbjct: 1019 IANITALKDQLLAAKHIQSKAIEARHASLMKRWTQLLANSATRKKKLLEAQSHFRKVEDL 1078
Query: 1128 YLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQD 949
+L FAKKAS FNSWFENAEEDLTDPVRCNSLEEI+ALR+AH F+ SLSSA+ DF QL +
Sbjct: 1079 FLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAE 1138
Query: 948 LDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAK 769
LDR+IKSF V NPYTWFTM+ALE+TWRNLQ+IIKERE EL +E +RQEENDKLR+EFA+
Sbjct: 1139 LDRQIKSFRVASNPYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQ 1198
Query: 768 LANAFHAWLTNTRQE------MMEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAML 607
ANAFH W+ TR M+E GTLE QL+A +RK +EI+A + QL++IE+ GA +
Sbjct: 1199 HANAFHQWIQETRTYLLDGSCMVEESGTLESQLEATKRKHQEIRAMRSQLKKIEDLGAAM 1258
Query: 606 ERNLILDNRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMMF 427
E LILDN+YTEHSTVG+AQ WDQLDQL MRMQHNLEQQIQARN +GV+EEAL+EFSMMF
Sbjct: 1259 EEALILDNKYTEHSTVGLAQQWDQLDQLGMRMQHNLEQQIQARNTTGVTEEALKEFSMMF 1318
Query: 426 KHFDKEKTGRLDHQQFKSCLRALGYDLPMVDEGQPEPEFQRILDIVDPNRDGYVTLQEYM 247
KHFDK+K+GRL+HQ+FKSCLR+LGYDLPMV+EG+P+PEF+ ILD VDPNRDG+V+LQEYM
Sbjct: 1319 KHFDKDKSGRLNHQEFKSCLRSLGYDLPMVEEGEPDPEFEAILDTVDPNRDGHVSLQEYM 1378
Query: 246 AFMISKETENIQSSEEIEMAFRALSKEFRPYVTAEELYANLTPEQAEFCIRRMKPYMDAI 67
AFMIS+ETEN++SSEEIE AFRALS E +PYVT EELY NLT EQA++C+ MKPY+D
Sbjct: 1379 AFMISRETENVKSSEEIESAFRALSSEGKPYVTKEELYQNLTREQADYCVSHMKPYVDG- 1437
Query: 66 SGRSIQGGLDYEQFVHALF 10
GR + DY +F +LF
Sbjct: 1438 KGRELPTAFDYVEFTRSLF 1456
Score = 674 bits (1738), Expect = 0.0
Identities = 420/1228 (34%), Positives = 644/1228 (52%), Gaps = 106/1228 (8%)
Frame = -1
Query: 6801 LQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYR 6622
L+++ K R+ +E+ WI EKE +T E++G DLE VE+LQ+KFDDF K+L ++ R
Sbjct: 73 LEKSCKKFMLFREANELQQWITEKEAALTNEEVGADLEQVEVLQKKFDDFQKDLKANESR 132
Query: 6621 INEINQAADKLVEEG-HSEHDQIYKKRD-------------------------------- 6541
+ +IN+ A+ L EG +E Q ++++
Sbjct: 133 LKDINKVAEDLESEGLMAEEVQAVQQQEVYGAMPRDEADSKTASPWKSARLMVHTVATFN 192
Query: 6540 ---DVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLN 6370
++N+ W L LA R + L AH+VQRF+RDADET WI EK+ AL++D+YG DL
Sbjct: 193 SIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLA 252
Query: 6369 NVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKE 6190
+VQALQRKHEG ERDLAAL K+ L + A +L ++HP+ AE + +K + AW +L +
Sbjct: 253 SVQALQRKHEGFERDLAALGDKVNSLGETAQRLIQSHPESAEDLKEKCTELNQAWTSLGK 312
Query: 6189 KAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKG 6010
+A RK L S L RFL+D+RDL+SWI ++ ++ +DELAKDV GAEALLE HQEH+
Sbjct: 313 RADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRT 372
Query: 6009 EIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMD 5830
EIDARA +F GQ+L+ G SPE++EKL+ LD E++ L W +RR++ + C++
Sbjct: 373 EIDARAGTFQAFEQFGQQLLAHGHYASPEIKEKLDILDQERTDLEKAWVQRRMMLDHCLE 432
Query: 5829 LQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDE 5650
LQLF+RD EQAE WM +EAFL D GDSLDSVE LIKKHEDF+K++ QEEKI AL
Sbjct: 433 LQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQA 492
Query: 5649 FATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSW 5470
FA +LI HYA D+A + + L ES Q F RD DE+ +W
Sbjct: 493 FADQLIAVDHYAKGDIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAW 552
Query: 5469 ITEKLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAA-- 5296
I+EKL TA D+SY DPTNI+ K QKH FE EL AN +R+ + G +I+ G A
Sbjct: 553 ISEKLQTASDESYKDPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSE 612
Query: 5295 DHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDY 5116
D + RL + + W LV + +K KL+EA +Q FN I+D + WLSE+E +ASEDY
Sbjct: 613 DAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDY 672
Query: 5115 GKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRY 4936
GKDL SV NL KK L+E+D +AH DR+ + A F+ + K++ + R+
Sbjct: 673 GKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKEKRDTINGRF 732
Query: 4935 NALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQ 4756
++ R+ KL ESH+ +Q FRD++DE +WI+EK+ + S + GRDL GVQNL KK
Sbjct: 733 QKIKSMATSRRAKLSESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKH 792
Query: 4755 QALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDL 4576
+ L AE+A H+ I+ V + EI+ +LAQ ++W+ LK A R L
Sbjct: 793 KRLEAELAAHEPAIQGVLDTGKKLSDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRL 852
Query: 4575 DDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSD-------- 4420
++SL+ Q++++ E +AW++EK +V S DYG + + LLKKH A +D
Sbjct: 853 EESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRV 912
Query: 4419 ------------------------LEAFKGTIEDLRKQASQCKYQEQPMGQLGRDCVLAL 4312
++ G + DL K A+Q K +L +
Sbjct: 913 NDVCTNGQDLIKKNNHHEENISSKMKGLNGKVSDLEKAAAQRK------AKLDENSAFLQ 966
Query: 4311 YDYQEK------SPREVSMKKGD-------VLTLLNASNRDWWKVEVNDRQGFVPAAYVK 4171
++++ +E S+K D V TLL ++ ++G +K
Sbjct: 967 FNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALK 1026
Query: 4170 RIEPGTAQQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQ--------L 4015
+ A +H Q + +I + + + ++ +L+ TRK+KL EA ++
Sbjct: 1027 --DQLLAAKHIQSK--AIEARHASLMKRWTQLLANSATRKKKLLEAQSHFRKVEDLFLTF 1082
Query: 4014 LREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATA 3835
++A+ W ++ E LE+++ L++ D F+ L + + ++ ++
Sbjct: 1083 AKKASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQ 1142
Query: 3834 LTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGS---------------AHEVQ 3700
+ S + + +E L WR L +L A
Sbjct: 1143 IKSF-RVASNPYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHAN 1201
Query: 3699 RFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKA 3520
FH+ + ETR ++ D + E+ G ++A +RKH+ ++ A+ ++K +++
Sbjct: 1202 AFHQWIQETRTYL--LDGSCMVEESGTLESQLEATKRKHQ----EIRAMRSQLKKIEDLG 1255
Query: 3519 NRLRQSHPEAAEQIYDLQRELNEQWNRL 3436
+ ++ + L +QW++L
Sbjct: 1256 AAMEEALILDNKYTEHSTVGLAQQWDQL 1283
Score = 344 bits (882), Expect = 2e-92
Identities = 296/1278 (23%), Positives = 564/1278 (43%), Gaps = 105/1278 (8%)
Frame = -1
Query: 5280 RLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLV 5101
R Q++N + L++ K+ L ++ + R +++ W++E E + +E+ G DL
Sbjct: 51 RQGQIDNQYQSLLELGEKRKGMLEKSCKKFMLFREANELQQWITEKEAALTNEEVGADLE 110
Query: 5100 SVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPV-IVRKQE---------- 4954
V+ LQKK + D A+ R+ I ++A+ + E V V++QE
Sbjct: 111 QVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYGAMPRDEA 170
Query: 4953 -------------------------NLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIED 4849
L +R+ +L+ E+R + LG +H+ + RD ++
Sbjct: 171 DSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADE 230
Query: 4848 ELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGH 4669
WI EK Q + N G DL VQ L +K + ++A ++ S+ A +IQ
Sbjct: 231 TKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAQRLIQSHP 290
Query: 4668 FLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGS 4489
A ++++K +L W L +A++R+ L DS ++LSD + +W++ +V S
Sbjct: 291 ESAEDLKEKCTELNQAWTSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSS 350
Query: 4488 TDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQC------------------- 4366
+ KD AEALL++H+ ++++A GT + + Q
Sbjct: 351 DELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKEKLDILD 410
Query: 4365 -------KYQEQPMGQLGRDCVLALYDYQ-EKSPREVSMKKGDVLTLLNASNRDWWKVEV 4210
K Q L L L+ E++ ++ ++ + T + D + +
Sbjct: 411 QERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALI 470
Query: 4209 NDRQGFVPAAYVKRIEPGTAQQHAQQQV-------NSIGGKQSEIEDKYQRLMMLGETRK 4051
+ F A V+ + Q A Q + I +++E+ D+++RL ++
Sbjct: 471 KKHEDFDKAINVQEEKIAALQAFADQLIAVDHYAKGDIANRRNEVLDRWRRLKAQMIEKR 530
Query: 4050 RKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANE 3871
KL E+ Q R+ +++ WI S + A E D ++ +K F+ +L AN
Sbjct: 531 SKLGESQTLQQFSRDVDEIEAWI-SEKLQTASDESYKDPTNIQSKHQKHQAFEAELHANA 589
Query: 3870 VRLQEMNQIATALTSVGQ---TETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQ 3700
R++ + + +L G +E AV+ R + L +W+ L +L A++ Q
Sbjct: 590 DRIRGVIDMGNSLIERGACAGSEDAVKAR--LAALADQWQFLVQKSAEKSQKLKEANKQQ 647
Query: 3699 RFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKA 3520
F+ + + W+ E + L SED+G+DL SV L +KH+ +E D++A D++K L+ +A
Sbjct: 648 NFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQA 707
Query: 3519 NRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIA 3340
+ L S Q+ + + +N ++ ++ S A +R+ KL +S+ +F D D WI
Sbjct: 708 DSLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKLSESHRLHQFFRDMDDEESWIK 767
Query: 3339 SMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDI 3160
LVSS++ D+TG + L ++H+ E+ + Q G +L + + +I
Sbjct: 768 EKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGQEEI 827
Query: 3159 ENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGD 2980
+ RL E K L+ AR L++ LE Q F + E+ + W++ + +A ED GD
Sbjct: 828 QQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASED-YGD 886
Query: 2979 N---VESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNG 2809
++ L+KKHE F+ ++++ + + LIK N++ ++ K + + +
Sbjct: 887 TLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKVSD 946
Query: 2808 LKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENY-RDPTNIQQKHQKQQA 2632
L++A Q++ KL E+ QF+ AD +E+W+ EK + ++Y RD +++Q KQ+
Sbjct: 947 LEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQET 1006
Query: 2631 FEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRL 2452
F+A L A A I A + + AK + A+ AR +L +W L+ + + +L
Sbjct: 1007 FDAGLQAFQQEGIANITALKDQLLAAKHIQSK-AIEARHASLMKRWTQLLANSATRKKKL 1065
Query: 2451 KEANKQ--------KSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEAD 2296
EA +F W E L L ++ L + H +
Sbjct: 1066 LEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSS 1125
Query: 2295 IVAHQ---DRVGEMNEQADSL--------------LENDQFQGQQIAERRKLIADRYDGV 2167
+ + Q +++ E++ Q S LE Q+I + R+L +
Sbjct: 1126 LSSAQADFNQLAELDRQIKSFRVASNPYTWFTMEALEETWRNLQKIIKERELELQK---- 1181
Query: 2166 KKMATDRRDKLSK--ALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHR 1993
++ + DKL + A + + F + I + +++ + +V ++ G ++ +RKH+
Sbjct: 1182 EQRRQEENDKLRQEFAQHANAFHQWIQETRTYLLDGSCMV--EESGTLESQLEATKRKHQ 1239
Query: 1992 RIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRME-DLEQSWGQIRDLTGNRH 1816
E+ + Q+ K E+L + EA + +++ + L Q W Q+ L
Sbjct: 1240 ----EIRAMRSQLK----KIEDLGAAMEEALILDNKYTEHSTVGLAQQWDQLDQLGMRMQ 1291
Query: 1815 QRLDESEAFQAFLGDVEE 1762
L++ + G EE
Sbjct: 1292 HNLEQQIQARNTTGVTEE 1309
Score = 340 bits (873), Expect = 2e-91
Identities = 250/940 (26%), Positives = 429/940 (45%), Gaps = 15/940 (1%)
Frame = -1
Query: 7137 SQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENF-RDPSNLQAKIQKHEAFEAE 6961
++ + L A + Q F RDADE WI EK Q +N+ D +++QA +KHE FE +
Sbjct: 208 AEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERD 267
Query: 6960 VQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKL 6781
+ A + +L +T +IQ + ++E +K++ EL+ W + KL + L
Sbjct: 268 LAALGDKVNSLGETAQRLIQSHPESAEDLKEKCTELNQAWTSLGKRADQRKAKLGDSHDL 327
Query: 6780 LHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQA 6601
F+ +++ WI V+++++ D+ E L + + E+ Q
Sbjct: 328 QRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQF 387
Query: 6600 ADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWI 6421
+L+ GH +I +K D ++ L R+ L ++Q F+RD ++ W+
Sbjct: 388 GQQLLAHGHYASPEIKEKLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWM 447
Query: 6420 GEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKL-AETHPDRAE 6244
++ L+++D G L++V+AL +KHE ++ + E K+ L+ A +L A H + +
Sbjct: 448 AAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAVDHYAKGD 507
Query: 6243 AIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELA 6064
+++N + W LK + ++ L S L +F D ++ +WI + K +DE
Sbjct: 508 IANRRN-EVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISE-KLQTASDESY 565
Query: 6063 KDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPE--VQEKLEKLDHE 5890
KD ++ + HQ + E+ A AD G L+E G E V+ +L L +
Sbjct: 566 KDPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQ 625
Query: 5889 KSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKK 5710
L+ E+ ++ Q F + + W+++ EA LA+ D G L SV +L+KK
Sbjct: 626 WQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKK 685
Query: 5709 HEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNA 5530
H+ E ++A E+++ L+ A L+ + V E R
Sbjct: 686 HQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAK 745
Query: 5529 LKESYKRQTFDRDCDEMVSWITE-KLSTARDDSYLDPTNIRGKLQKHINFEQELKANENR 5353
L ES++ F RD D+ SWI E KL + +D D T ++ +KH E EL A+E
Sbjct: 746 LSESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPA 805
Query: 5352 LDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNI 5173
+ + TG+++ D + I RL Q W EL +G +L E+ QQF N+
Sbjct: 806 IQGVLDTGKKLSDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANV 865
Query: 5172 EDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEE 4993
E+ EAW++E VASEDYG L ++Q L KK E+DF H DRV+ + Q ++
Sbjct: 866 EEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKK 925
Query: 4992 EHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVA 4813
+ + I K + L + + L +RK KL E+ Q + +WI EKE
Sbjct: 926 NNHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSL 985
Query: 4812 GSTNRGRDLIGVQNLIKKQQALIAEI-ANHDSQIESVSSAANDMIQQGHFLAPEIRDKLA 4636
+ + GRDL VQ L+ KQ+ A + A I ++++ + ++ H + I + A
Sbjct: 986 KTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHA 1045
Query: 4635 QLRDNWRILKSKAEKRRTDLDDSLQAH------QYLSDANEADA---WMSEKEPIVGSTD 4483
L W L + + R+ L ++ Q+H +L+ A +A A W E +
Sbjct: 1046 SLMKRWTQLLANSATRKKKLLEA-QSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPV 1104
Query: 4482 YGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCK 4363
+ +AL + H A S L + + L + Q K
Sbjct: 1105 RCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIK 1144
Score = 315 bits (808), Expect = 8e-84
Identities = 306/1278 (23%), Positives = 544/1278 (41%), Gaps = 123/1278 (9%)
Frame = -1
Query: 6207 WNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLES 6028
+ +L E + RK LE+S + + +L WI + +A + +E+ D+ E L +
Sbjct: 59 YQSLLELGEKRKGMLEKSCKKFMLFREANELQQWITEKEAALTNEEVGADLEQVEVLQKK 118
Query: 6027 HQEHKGEIDARADSFNQTASAGQKLVEMGI--PESPEVQEK------------------- 5911
+ + ++ A + L G+ E VQ++
Sbjct: 119 FDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYGAMPRDEADSKTASPW 178
Query: 5910 ---------------LEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQ 5776
+++L+ SL L EER L ++Q F+RD ++ + W+ ++
Sbjct: 179 KSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEK 238
Query: 5775 EAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAE 5596
L + G L SV+ L +KHE FE+ LAA +K+N+L E A +LIQ +A+D+ E
Sbjct: 239 NQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAQRLIQSHPESAEDLKE 298
Query: 5595 XXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITE-KLSTARDDSYLDPT 5419
R L +S+ Q F D +++SWI + + D+ D T
Sbjct: 299 KCTELNQAWTSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVT 358
Query: 5418 NIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVD 5239
L++H E+ A G+Q++ GH+A+ I ++L ++ +L
Sbjct: 359 GAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKEKLDILDQERTDLEK 418
Query: 5238 ATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIES 5059
A ++ L Q F+R+ E E W++ E + +ED G L SV+ L KK +
Sbjct: 419 AWVQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDK 478
Query: 5058 DFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQ 4879
N +++ ++ A Q +H+ I ++ + R+ L+ + +++ KLGES
Sbjct: 479 AINVQEEKIAALQAFADQLIAVDHYAKGDIANRRNEVLDRWRRLKAQMIEKRSKLGESQT 538
Query: 4878 GNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSS 4699
Q RD+++ AWI EK Q A S +D +Q+ +K QA AE+ + +I V
Sbjct: 539 LQQFSRDVDEIEAWISEKLQTA-SDESYKDPTNIQSKHQKHQAFEAELHANADRIRGVID 597
Query: 4698 AANDMIQQGHFLAPE--IRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEAD 4525
N +I++G E ++ +LA L D W+ L K+ ++ L ++ + + + + D
Sbjct: 598 MGNSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFD 657
Query: 4524 AWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQA---------- 4375
W+SE E ++ S DYGKD S LLKKH+ L +D+ A + ++DL QA
Sbjct: 658 FWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFD 717
Query: 4374 -SQCK---------YQEQPMGQLGRDCVLA----LYD-YQEKSPREVSMKKGDVLTLLNA 4240
SQ K +Q+ R L+ L+ +++ E +K+ +L
Sbjct: 718 TSQVKEKRDTINGRFQKIKSMATSRRAKLSESHRLHQFFRDMDDEESWIKEKKLLVSSED 777
Query: 4239 SNRDWWKVEVNDRQGFVPAAYVKRIEPG-TAQQHAQQQVNSIGGK--------QSEIEDK 4087
RD V+ N R+ KR+E A + A Q V G K Q EI+ +
Sbjct: 778 YGRDLTGVQ-NLRKKH------KRLEAELAAHEPAIQGVLDTGKKLSDDNTIGQEEIQQR 830
Query: 4086 -------YQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQ 3928
++ L L R ++LEE+ + Q + + WI + + A ++ G L
Sbjct: 831 LAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAA 890
Query: 3927 VEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXX 3748
++ L KK + F+ D ++ R+ ++ L I +++ LN + L
Sbjct: 891 IQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEE-NISSKMKGLNGKVSDLEK 949
Query: 3747 XXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVER 3568
+L +F+ D WI EK+++L ++D+GRDL SVQ L K E +
Sbjct: 950 AAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDA 1009
Query: 3567 DLAALGDK-IKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSY 3391
L A + I ++ ++L + ++ I L ++W +L + + RK+KLL++
Sbjct: 1010 GLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHASLMKRWTQLLANSATRKKKLLEAQ 1069
Query: 3390 DYQRFLSDY--------RDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSR 3235
+ R + D W + + ++ N + +AL E H +R+ + S
Sbjct: 1070 SHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSA 1129
Query: 3234 AATFQAFDQFGNQL----LNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNIL-DQCLE 3070
A F + Q+ + S+ Y +E LE+ W + I+ ++ LE
Sbjct: 1130 QADFNQLAELDRQIKSFRVASNPYTWFTME-----------ALEETWRNLQKIIKERELE 1178
Query: 3069 LQLFYRDCEQAD--------------TWMSAREAFL----AQEDPSG---DNVESLIKKH 2953
LQ R E+ D W+ +L + SG +E+ +KH
Sbjct: 1179 LQKEQRRQEENDKLRQEFAQHANAFHQWIQETRTYLLDGSCMVEESGTLESQLEATKRKH 1238
Query: 2952 EDFDKAINTQEEKIKGL-KLFAESLIKNNHYDSPAVT------RKRDQILDRWNGLKEAL 2794
++ +A+ +Q +KI+ L E+LI +N Y + + DQ+ R E
Sbjct: 1239 QEI-RAMRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQQWDQLDQLGMRMQHNLEQQ 1297
Query: 2793 IQKRFKLG-ESQTLQQFS 2743
IQ R G + L++FS
Sbjct: 1298 IQARNTTGVTEEALKEFS 1315
Score = 311 bits (797), Expect = 2e-82
Identities = 288/1299 (22%), Positives = 555/1299 (42%), Gaps = 121/1299 (9%)
Frame = -1
Query: 5979 QTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQ 5800
Q+AS L E G + + ++D++ SLL L E+R+ + E+ + +R+ +
Sbjct: 34 QSASRENLLEEQG-----SIALRQGQIDNQYQSLLELGEKRKGMLEKSCKKFMLFREANE 88
Query: 5799 AETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKL----- 5635
+ W+ ++EA L N ++G L+ VE L KK +DF+K L A E ++ +++ A L
Sbjct: 89 LQQWITEKEAALTNEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGL 148
Query: 5634 -------IQGQH-YAA--DDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKR-------- 5509
+Q Q Y A D A+ N++KE +R
Sbjct: 149 MAEEVQAVQQQEVYGAMPRDEADSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLA 208
Query: 5508 -------------QTFDRDCDEMVSWITEKLSTARDDSY-LDPTNIRGKLQKHINFEQEL 5371
Q F RD DE WI EK D+Y D +++ +KH FE++L
Sbjct: 209 EERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDL 268
Query: 5370 KANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQ 5191
A ++++ + T +++I S +A+ + ++ ++N W L +++ AKL ++ + Q
Sbjct: 269 AALGDKVNSLGETAQRLIQSHPESAEDLKEKCTELNQAWTSLGKRADQRKAKLGDSHDLQ 328
Query: 5190 QFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLA 5011
+F + D+ +W++ + G V+S++ KD+ + L ++ ++ +A +Q
Sbjct: 329 RFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFG 388
Query: 5010 QQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIR 4831
QQ H+ +P I K + L Q L +R+ L + RD E W+
Sbjct: 389 QQLLAHGHYASPEIKEKLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWMA 448
Query: 4830 EKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEI 4651
+E + ++G L V+ LIKK + I + +I ++ + A+ +I H+ +I
Sbjct: 449 AREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAVDHYAKGDI 508
Query: 4650 RDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKD 4471
++ ++ D WR LK++ ++R+ L +S Q+ D +E +AW+SEK Y KD
Sbjct: 509 ANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESY-KD 567
Query: 4470 EDSAEALLKKHRALLSDLEA----FKGTIE---DLRKQASQCKYQEQPMGQLGRDCVLAL 4312
+ ++ +KH+A ++L A +G I+ L ++ + ++ +L
Sbjct: 568 PTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQ 627
Query: 4311 YDYQEKSPREVSMKKGDVLTLLNASNR--DWWKVEVN-------------------DRQG 4195
+ Q+ + + +K+ + N + D+W EV +
Sbjct: 628 FLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQ 687
Query: 4194 FVPA---AYVKRIEPGTAQQHAQQ-----QVNSIGGKQSEIEDKYQRLMMLGETRKRKLE 4039
+ A A+ R++ +Q + + + K+ I ++Q++ + +R+ KL
Sbjct: 688 LLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKLS 747
Query: 4038 EACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQ 3859
E+ + +Q R+ +D WIK ++ + + ++ G DL V+ L+KK + +L A+E +Q
Sbjct: 748 ESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQ 807
Query: 3858 EMNQIATALT---SVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHR 3688
+ L+ ++GQ E R+ Q +E W+ L +L + E Q+F
Sbjct: 808 GVLDTGKKLSDDNTIGQEEIQQRLAQFVE----HWKELKQLAAARGQRLEESLEYQQFVA 863
Query: 3687 DVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLR 3508
+V+E WI EK + SED+G L ++Q L +KHE E D D++ + L
Sbjct: 864 NVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLI 923
Query: 3507 QSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQ 3328
+ + E I + LN + + L A RK KL ++ + +F + WI
Sbjct: 924 KKNNHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKEN 983
Query: 3327 LVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFG--------NQLLNSHHYA 3172
+ + + D++ + LL + + + A QAF Q G +QLL + H
Sbjct: 984 SLKTDDYGRDLSSVQTLLTKQETF-------DAGLQAFQQEGIANITALKDQLLAAKHIQ 1036
Query: 3171 AGDIENR-----------LQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWM 3025
+ IE R L +K L +A R + D L F + ++W
Sbjct: 1037 SKAIEARHASLMKRWTQLLANSATRKKKLLEAQSHFRKVEDLFL---TFAKKASAFNSWF 1093
Query: 3024 SAREAFLAQEDP----SGDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDS 2857
E L DP S + +++L + H+ F ++++ + L + +
Sbjct: 1094 ENAEEDLT--DPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASN 1151
Query: 2856 PAVTRKRDQILDRWNGLKEALIQKRFKLGESQ--------TLQQFSRDADEIENWMTEKF 2701
P + + + W L++ + ++ +L + Q Q+F++ A+ W+ E
Sbjct: 1152 PYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETR 1211
Query: 2700 QIAQE-----------ENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQA---GNNLI 2563
+ E+ + T ++KHQ+ +A ++L D AA+ +A N
Sbjct: 1212 TYLLDGSCMVEESGTLESQLEAT--KRKHQEIRAMRSQLKKIEDLGAAMEEALILDNKYT 1269
Query: 2562 ENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKE 2446
E++ G L QWD L + + L++
Sbjct: 1270 EHSTVG------------LAQQWDQLDQLGMRMQHNLEQ 1296
Score = 281 bits (719), Expect = 2e-73
Identities = 205/801 (25%), Positives = 359/801 (44%), Gaps = 46/801 (5%)
Frame = -1
Query: 7194 DIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENFR 7015
DI RR EVL + K KR +L E++ Q F RD DE+ WI EKLQTA +E+++
Sbjct: 507 DIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYK 566
Query: 7014 DPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEH--IKKRLEELHALW 6841
DP+N+Q+K QKH+AFEAE+ A+A I + GN++I+ A +K RL L W
Sbjct: 567 DPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQW 626
Query: 6840 XXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKF 6661
K KL++A K +F + +W+ E E + +ED G DL V L +K
Sbjct: 627 QFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKH 686
Query: 6660 DDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGL 6481
++ H+ R+ ++N AD L+ + Q+ +KRD +N + ++ ++A +R+ L
Sbjct: 687 QLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKL 746
Query: 6480 FGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKM 6301
+H++ +F RD D+ +WI EK L +SS+DYGRDL VQ L++KH+ E +LAA E +
Sbjct: 747 SESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAI 806
Query: 6300 LQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYR 6121
+ KL++ + E I Q+ W LK+ A R LE S + +F+A+
Sbjct: 807 QGVLDTGKKLSDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVE 866
Query: 6120 DLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMG 5941
+ +WI + ++ +++ +A + LL+ H+ + + D N + GQ L++
Sbjct: 867 EEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKN 926
Query: 5940 IPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLA 5761
+ K++ L+ + S L +R+ ++ F + E+W+ ++E L
Sbjct: 927 NHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLK 986
Query: 5760 NTDLGDSLDSVEHLIKKHEDFEKSLAA-QEEKINALDEFATKLIQGQHYAADDVAEXXXX 5584
D G L SV+ L+ K E F+ L A Q+E I + +L+ +H + +
Sbjct: 987 TDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHAS 1046
Query: 5583 XXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTAR------DDSYLDP 5422
R L E+ Q+ R +++ +K S ++ DP
Sbjct: 1047 LMKRWTQLLANSATRKKKLLEA---QSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDP 1103
Query: 5421 T------NIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNN 5260
I+ + H F L + + + + QI + + + +
Sbjct: 1104 VRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFTMEALEE 1163
Query: 5259 LWNELVDATNKKGAKL-----REAGNE---QQFNRNIEDVEAWLSE-----LEGQVASED 5119
W L ++ +L R+ N+ Q+F ++ W+ E L+G E+
Sbjct: 1164 TWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRTYLLDGSCMVEE 1223
Query: 5118 YG---KDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQ---------------LAQQFQEE 4993
G L + + ++I + S D +++ LAQQ+ +
Sbjct: 1224 SGTLESQLEATKRKHQEIRAMRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQQWDQL 1283
Query: 4992 EHFNAPVIVRKQENLQQRYNA 4930
+ +R Q NL+Q+ A
Sbjct: 1284 DQLG----MRMQHNLEQQIQA 1300
Score = 107 bits (268), Expect = 3e-21
Identities = 78/312 (25%), Positives = 136/312 (43%), Gaps = 10/312 (3%)
Frame = -1
Query: 7197 DDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENF 7018
++I QR + + H+ K + + RLEE+ ++Q F + +E WI EK+ E++
Sbjct: 825 EEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDY 884
Query: 7017 RDP-SNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALW 6841
D + +Q ++KHEAFE + H + ++ G +I+ N+ E+I +++ L+
Sbjct: 885 GDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKV 944
Query: 6840 XXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKF 6661
+ KL + L F + D + WI EKE + +D G DL V+ L K
Sbjct: 945 SDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQ 1004
Query: 6660 DDFLKELGNHQYR-INEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEG 6484
+ F L Q I I D+L+ H + I + + W +L +ATRK+
Sbjct: 1005 ETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHASLMKRWTQLLANSATRKKK 1064
Query: 6483 LFGAHQVQR--------FNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTER 6328
L A R F + A +W + L+ L ++AL+ H+
Sbjct: 1065 LLEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRS 1124
Query: 6327 DLAALEGKMLQL 6292
L++ + QL
Sbjct: 1125 SLSSAQADFNQL 1136
>gi|20380003|gb|AAH27791.1| Spna2 protein [Mus musculus]
Length = 1359
Score = 1618 bits (4191), Expect = 0.0
Identities = 811/1358 (59%), Positives = 1015/1358 (74%), Gaps = 43/1358 (3%)
Frame = -1
Query: 3954 QEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQ---- 3787
+E+G DLEQVEVLQKKFDDF+ DLKANE RL+++N++A L S G V+ QQ
Sbjct: 4 REVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVY 63
Query: 3786 -------------------------------IEDLNARWRALXXXXXXXXXQLGSAHEVQ 3700
I++LN RWR+L LGSAHEVQ
Sbjct: 64 GAMPRDEADSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQ 123
Query: 3699 RFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKA 3520
RFHRD DET++WI+EK+ AL+++++G DL SVQALQRKHEG ERDLAALGDK+ SL E A
Sbjct: 124 RFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETA 183
Query: 3519 NRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIA 3340
RL QSHPE+AE + + ELN+ W L +A+ RK KL DS+D QRFLSD+RDLM WI
Sbjct: 184 QRLIQSHPESAEDLKEKCTELNQAWTSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWIN 243
Query: 3339 SMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDI 3160
+ LVSS ELA DVTGAEALLERHQE+RTEID+RA TFQAF+QFG QLL HYA+ +I
Sbjct: 244 GIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEI 303
Query: 3159 ENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDP--S 2986
+ +L +++ R LE AWV RR +LD CLELQLF+RDCEQA+ WM+AREAFL ED S
Sbjct: 304 KEKLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDS 363
Query: 2985 GDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGL 2806
D+VE+LIKKHEDFDKAIN QEEKI L+ FA+ LI +HY + +R+++LDRW L
Sbjct: 364 LDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAVDHYAKGDIANRRNEVLDRWRRL 423
Query: 2805 KEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNIQQKHQKQQAFE 2626
K +I+KR KLGESQTLQQFSRD DEIE W++EK Q A +E+Y+DPTNIQ KHQK QAFE
Sbjct: 424 KAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPTNIQSKHQKHQAFE 483
Query: 2625 AELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKE 2446
AELHAN+DRI +I GN+LIE C G E AV ARL AL DQW LV+ + EKS +LKE
Sbjct: 484 AELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKE 543
Query: 2445 ANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGE 2266
ANKQ++F +KD +FWL EVE LL SEDYGKDLASV NLLKKH LLEADI AH+DR+ +
Sbjct: 544 ANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKD 603
Query: 2265 MNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDE 2086
+N QADSL+ + F Q+ E+R I R+ +K MAT RR KLS++ +HQFFRD+DDE
Sbjct: 604 LNSQADSLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKLSESHRLHQFFRDMDDE 663
Query: 2085 ESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAE 1906
ESWIKEKKLLVSS+DYGRDL GVQNLR+KH+R++ ELA+HEP + V G++L + +
Sbjct: 664 ESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKL---SDD 720
Query: 1905 AGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQIL 1726
+G+++I++R+ + W +++ L R QRL+ES +Q F+ +VEEEEAW+NEK ++
Sbjct: 721 NTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLV 780
Query: 1725 GSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQ 1546
S+++G+ +A +QGLLKKH+ F+ D +HK RV D+ G LI NHH +I +
Sbjct: 781 ASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKG 840
Query: 1545 LRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQI 1366
L ++ ++E A R AKL +NSA+LQF WK DVVESWI EKE ++++D+GRDLSSVQ
Sbjct: 841 LNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQT 900
Query: 1365 LLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSE 1186
LLTKQE FDAGL AF+ EGI IT LKDQL++++H QS AIE RH ++++RW LLA+S
Sbjct: 901 LLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHASLMKRWTQLLANSA 960
Query: 1185 ARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAH 1006
R+ ++E+L+L FAKKAS FNSWFENAEEDLTDPVRCNSLEEI+ALR+AH
Sbjct: 961 TRKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEIKALREAH 1020
Query: 1005 GEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQEL 826
F+ SLSSA+ DF QL +LDR+IKSF V NPYTWFTM+ALE+TWRNLQ+IIKERE EL
Sbjct: 1021 DAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFTMEALEETWRNLQKIIKERELEL 1080
Query: 825 AREHQRQEENDKLRREFAKLANAFHAWLTNTRQE------MMEAGGTLEEQLDAVERKAK 664
+E +RQEENDKLR+EFA+ ANAFH W+ TR M+E GTLE QL+A +RK +
Sbjct: 1081 QKEQRRQEENDKLRQEFAQHANAFHQWIQETRTYLLDGSCMVEESGTLESQLEATKRKHQ 1140
Query: 663 EIKANKGQLRQIEEKGAMLERNLILDNRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQ 484
EI+A + QL++IE+ GA +E LILDN+YTEHSTVG+AQ WDQLDQL MRMQHNLEQQIQ
Sbjct: 1141 EIRAMRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQQWDQLDQLGMRMQHNLEQQIQ 1200
Query: 483 ARNQSGVSEEALREFSMMFKHFDKEKTGRLDHQQFKSCLRALGYDLPMVDEGQPEPEFQR 304
ARN +GV+EEAL+EFSMMFKHFDK+K+GRL+HQ+FKSCLR+LGYDLPMV+EG+P+PEF+
Sbjct: 1201 ARNTTGVTEEALKEFSMMFKHFDKDKSGRLNHQEFKSCLRSLGYDLPMVEEGEPDPEFEA 1260
Query: 303 ILDIVDPNRDGYVTLQEYMAFMISKETENIQSSEEIEMAFRALSKEFRPYVTAEELYANL 124
ILD VDPNRDG+V+LQEYMAFMIS+ETEN++SSEEIE AFRALS E +PYVT EELY NL
Sbjct: 1261 ILDTVDPNRDGHVSLQEYMAFMISRETENVKSSEEIESAFRALSSEGKPYVTKEELYQNL 1320
Query: 123 TPEQAEFCIRRMKPYMDAISGRSIQGGLDYEQFVHALF 10
T EQA++C+ MKPY+D GR + DY +F +LF
Sbjct: 1321 TREQADYCVSHMKPYVDG-KGRELPTAFDYVEFTRSLF 1357
Score = 652 bits (1682), Expect = 0.0
Identities = 409/1197 (34%), Positives = 626/1197 (52%), Gaps = 106/1197 (8%)
Frame = -1
Query: 6708 DMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEG-HSEHDQIYKKRD--- 6541
++G DLE VE+LQ+KFDDF K+L ++ R+ +IN+ A+ L EG +E Q ++++
Sbjct: 5 EVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYG 64
Query: 6540 --------------------------------DVNDAWHRLNTLAATRKEGLFGAHQVQR 6457
++N+ W L LA R + L AH+VQR
Sbjct: 65 AMPRDEADSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQR 124
Query: 6456 FNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAH 6277
F+RDADET WI EK+ AL++D+YG DL +VQALQRKHEG ERDLAAL K+ L + A
Sbjct: 125 FHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAQ 184
Query: 6276 KLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGD 6097
+L ++HP+ AE + +K + AW +L ++A RK L S L RFL+D+RDL+SWI
Sbjct: 185 RLIQSHPESAEDLKEKCTELNQAWTSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWING 244
Query: 6096 MKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQ 5917
++ ++ +DELAKDV GAEALLE HQEH+ EIDARA +F GQ+L+ G SPE++
Sbjct: 245 IRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIK 304
Query: 5916 EKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSL 5737
EKL+ LD E++ L W +RR++ + C++LQLF+RD EQAE WM +EAFL D GDSL
Sbjct: 305 EKLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSL 364
Query: 5736 DSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXX 5557
DSVE LIKKHEDF+K++ QEEKI AL FA +LI HYA D+A
Sbjct: 365 DSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAVDHYAKGDIANRRNEVLDRWRRLK 424
Query: 5556 XXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQ 5377
+ + L ES Q F RD DE+ +WI+EKL TA D+SY DPTNI+ K QKH FE
Sbjct: 425 AQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPTNIQSKHQKHQAFEA 484
Query: 5376 ELKANENRLDDIRSTGEQIIDSGHFAA--DHIGDRLRQVNNLWNELVDATNKKGAKLREA 5203
EL AN +R+ + G +I+ G A D + RL + + W LV + +K KL+EA
Sbjct: 485 ELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEA 544
Query: 5202 GNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGI 5023
+Q FN I+D + WLSE+E +ASEDYGKDL SV NL KK L+E+D +AH DR+ +
Sbjct: 545 NKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDL 604
Query: 5022 KQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDEL 4843
A F+ + K++ + R+ ++ R+ KL ESH+ +Q FRD++DE
Sbjct: 605 NSQADSLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKLSESHRLHQFFRDMDDEE 664
Query: 4842 AWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFL 4663
+WI+EK+ + S + GRDL GVQNL KK + L AE+A H+ I+ V +
Sbjct: 665 SWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIG 724
Query: 4662 APEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTD 4483
EI+ +LAQ ++W+ LK A R L++SL+ Q++++ E +AW++EK +V S D
Sbjct: 725 QEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASED 784
Query: 4482 YGKDEDSAEALLKKHRALLSD--------------------------------LEAFKGT 4399
YG + + LLKKH A +D ++ G
Sbjct: 785 YGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGK 844
Query: 4398 IEDLRKQASQCKYQEQPMGQLGRDCVLALYDYQEK------SPREVSMKKGD-------V 4258
+ DL K A+Q K +L + ++++ +E S+K D V
Sbjct: 845 VSDLEKAAAQRK------AKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSV 898
Query: 4257 LTLLNASNRDWWKVEVNDRQGFVPAAYVKRIEPGTAQQHAQQQVNSIGGKQSEIEDKYQR 4078
TLL ++ ++G +K + A +H Q + +I + + + ++ +
Sbjct: 899 QTLLTKQETFDAGLQAFQQEGIANITALK--DQLLAAKHIQSK--AIEARHASLMKRWTQ 954
Query: 4077 LMMLGETRKRKLEEACKGYQ--------LLREANDLAEWIKSREAVAAQQEIGTDLEQVE 3922
L+ TRK+KL EA ++ ++A+ W ++ E LE+++
Sbjct: 955 LLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEIK 1014
Query: 3921 VLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXX 3742
L++ D F+ L + + ++ ++ + S + + +E L WR L
Sbjct: 1015 ALREAHDAFRSSLSSAQADFNQLAELDRQIKSF-RVASNPYTWFTMEALEETWRNLQKII 1073
Query: 3741 XXXXXQLGS---------------AHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRS 3607
+L A FH+ + ETR ++ D + E+ G
Sbjct: 1074 KERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRTYL--LDGSCMVEESGTLESQ 1131
Query: 3606 VQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRL 3436
++A +RKH+ ++ A+ ++K +++ + ++ + L +QW++L
Sbjct: 1132 LEATKRKHQ----EIRAMRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQQWDQL 1184
Score = 397 bits (1020), Expect = e-108
Identities = 272/1153 (23%), Positives = 539/1153 (46%), Gaps = 23/1153 (1%)
Frame = -1
Query: 4143 HAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAV 3964
H NSI E+ ++++ L L E R + L A + + R+A++ EWI+ +
Sbjct: 87 HTVATFNSI----KELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQA 142
Query: 3963 AAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQI 3784
G DL V+ LQ+K + F+ DL A ++ + + A L E+A ++++
Sbjct: 143 LNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAQRLIQ-SHPESAEDLKEKC 201
Query: 3783 EDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSV 3604
+LN W +L +LG +H++QRF D + WI + S++ +D+
Sbjct: 202 TELNQAWTSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGA 261
Query: 3603 QALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKA 3424
+AL +H+ ++ A ++ ++ +L A+ +I + L+++ L
Sbjct: 262 EALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKEKLDILDQERTDLEKAW 321
Query: 3423 NNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEI 3244
R+ L + Q F D W+A+ +++++ + + EAL+++H+++ I
Sbjct: 322 VQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAI 381
Query: 3243 DSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQ 3064
+ + A F +QL+ HYA GDI NR V + + L+ + +R+ L + LQ
Sbjct: 382 NVQEEKIAALQAFADQLIAVDHYAKGDIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQ 441
Query: 3063 LFYRDCEQADTWMSAREAFLAQE---DPSGDNVESLIKKHEDFDKAINTQEEKIKGLKLF 2893
F RD ++ + W+S + + E DP+ N++S +KH+ F+ ++ ++I+G+
Sbjct: 442 QFSRDVDEIEAWISEKLQTASDESYKDPT--NIQSKHQKHQAFEAELHANADRIRGVIDM 499
Query: 2892 AESLIKNNHY--DSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIEN 2719
SLI+ AV + + D+W L + +K KL E+ Q F+ + +
Sbjct: 500 GNSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDF 559
Query: 2718 WMTEKFQIAQEENY-RDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGG 2542
W++E + E+Y +D ++ +K Q EA++ A+ DR+ + ++L+ ++
Sbjct: 560 WLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDT 619
Query: 2541 GEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSE 2362
+ V + +N ++ + T + +L E+++ F + D E W+ E ++L+ SE
Sbjct: 620 SQ--VKEKRDTINGRFQKIKSMATSRRAKLSESHRLHQFFRDMDDEESWIKEKKLLVSSE 677
Query: 2361 DYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIAD 2182
DYG+DL V+NL KKH LEA++ AH+ + + + L +++ ++I +R +
Sbjct: 678 DYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGQEEIQQRLAQFVE 737
Query: 2181 RYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRR 2002
+ +K++A R +L ++L QF ++++EE+WI EK LV+S+DYG L +Q L +
Sbjct: 738 HWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLK 797
Query: 2001 KHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGN 1822
KH +T+ H+ +V+ V G++L++ + E+ I +M+ L +
Sbjct: 798 KHEAFETDFTVHKDRVNDVCTNGQDLIK---KNNHHEENISSKMKGLNGKVSDLEKAAAQ 854
Query: 1821 RHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLEL 1642
R +LDE+ AF F + E+W+ EK+ L +D++G +++ VQ LL K +TF L+
Sbjct: 855 RKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQA 914
Query: 1641 HKQR-VADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRD------ 1483
+Q +A++ D L+ + + I+ R L R ++ + + R KL +
Sbjct: 915 FQQEGIANITALKDQLLAAKHIQSKAIEARHASLMKRWTQLLANSATRKKKLLEAQSHFR 974
Query: 1482 --NSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEG 1309
+L F K SW E+ + L ++ L +AF + L++ + +
Sbjct: 975 KVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQAD- 1033
Query: 1308 IQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEEL 1129
++ EL Q+ S +P + + W+NL + R + ++L
Sbjct: 1034 FNQLAELDRQIKSFRVASNPYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKL 1093
Query: 1128 YLAFAKKASTFNSWFENAEEDLTD----PVRCNSLE-EIRALRDAHGEFQRSLSSAEEDF 964
FA+ A+ F+ W + L D +LE ++ A + H E + +
Sbjct: 1094 RQEFAQHANAFHQWIQETRTYLLDGSCMVEESGTLESQLEATKRKHQE----IRAMRSQL 1149
Query: 963 RQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEE---ND 793
++++DL ++ + N YT + L W L ++ + L ++ Q + +
Sbjct: 1150 KKIEDLGAAMEEALILDNKYTEHSTVGLAQQWDQLDQLGMRMQHNLEQQIQARNTTGVTE 1209
Query: 792 KLRREFAKLANAF 754
+ +EF+ + F
Sbjct: 1210 EALKEFSMMFKHF 1222
Score = 340 bits (873), Expect = 2e-91
Identities = 250/940 (26%), Positives = 429/940 (45%), Gaps = 15/940 (1%)
Frame = -1
Query: 7137 SQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENF-RDPSNLQAKIQKHEAFEAE 6961
++ + L A + Q F RDADE WI EK Q +N+ D +++QA +KHE FE +
Sbjct: 109 AEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERD 168
Query: 6960 VQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKL 6781
+ A + +L +T +IQ + ++E +K++ EL+ W + KL + L
Sbjct: 169 LAALGDKVNSLGETAQRLIQSHPESAEDLKEKCTELNQAWTSLGKRADQRKAKLGDSHDL 228
Query: 6780 LHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQA 6601
F+ +++ WI V+++++ D+ E L + + E+ Q
Sbjct: 229 QRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQF 288
Query: 6600 ADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWI 6421
+L+ GH +I +K D ++ L R+ L ++Q F+RD ++ W+
Sbjct: 289 GQQLLAHGHYASPEIKEKLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWM 348
Query: 6420 GEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKL-AETHPDRAE 6244
++ L+++D G L++V+AL +KHE ++ + E K+ L+ A +L A H + +
Sbjct: 349 AAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAVDHYAKGD 408
Query: 6243 AIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELA 6064
+++N + W LK + ++ L S L +F D ++ +WI + K +DE
Sbjct: 409 IANRRN-EVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISE-KLQTASDESY 466
Query: 6063 KDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPE--VQEKLEKLDHE 5890
KD ++ + HQ + E+ A AD G L+E G E V+ +L L +
Sbjct: 467 KDPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQ 526
Query: 5889 KSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKK 5710
L+ E+ ++ Q F + + W+++ EA LA+ D G L SV +L+KK
Sbjct: 527 WQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKK 586
Query: 5709 HEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNA 5530
H+ E ++A E+++ L+ A L+ + V E R
Sbjct: 587 HQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAK 646
Query: 5529 LKESYKRQTFDRDCDEMVSWITE-KLSTARDDSYLDPTNIRGKLQKHINFEQELKANENR 5353
L ES++ F RD D+ SWI E KL + +D D T ++ +KH E EL A+E
Sbjct: 647 LSESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPA 706
Query: 5352 LDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNI 5173
+ + TG+++ D + I RL Q W EL +G +L E+ QQF N+
Sbjct: 707 IQGVLDTGKKLSDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANV 766
Query: 5172 EDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEE 4993
E+ EAW++E VASEDYG L ++Q L KK E+DF H DRV+ + Q ++
Sbjct: 767 EEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKK 826
Query: 4992 EHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVA 4813
+ + I K + L + + L +RK KL E+ Q + +WI EKE
Sbjct: 827 NNHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSL 886
Query: 4812 GSTNRGRDLIGVQNLIKKQQALIAEI-ANHDSQIESVSSAANDMIQQGHFLAPEIRDKLA 4636
+ + GRDL VQ L+ KQ+ A + A I ++++ + ++ H + I + A
Sbjct: 887 KTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHA 946
Query: 4635 QLRDNWRILKSKAEKRRTDLDDSLQAH------QYLSDANEADA---WMSEKEPIVGSTD 4483
L W L + + R+ L ++ Q+H +L+ A +A A W E +
Sbjct: 947 SLMKRWTQLLANSATRKKKLLEA-QSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPV 1005
Query: 4482 YGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCK 4363
+ +AL + H A S L + + L + Q K
Sbjct: 1006 RCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIK 1045
Score = 281 bits (719), Expect = 2e-73
Identities = 205/801 (25%), Positives = 359/801 (44%), Gaps = 46/801 (5%)
Frame = -1
Query: 7194 DIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENFR 7015
DI RR EVL + K KR +L E++ Q F RD DE+ WI EKLQTA +E+++
Sbjct: 408 DIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYK 467
Query: 7014 DPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEH--IKKRLEELHALW 6841
DP+N+Q+K QKH+AFEAE+ A+A I + GN++I+ A +K RL L W
Sbjct: 468 DPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQW 527
Query: 6840 XXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKF 6661
K KL++A K +F + +W+ E E + +ED G DL V L +K
Sbjct: 528 QFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKH 587
Query: 6660 DDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGL 6481
++ H+ R+ ++N AD L+ + Q+ +KRD +N + ++ ++A +R+ L
Sbjct: 588 QLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKL 647
Query: 6480 FGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKM 6301
+H++ +F RD D+ +WI EK L +SS+DYGRDL VQ L++KH+ E +LAA E +
Sbjct: 648 SESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAI 707
Query: 6300 LQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYR 6121
+ KL++ + E I Q+ W LK+ A R LE S + +F+A+
Sbjct: 708 QGVLDTGKKLSDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVE 767
Query: 6120 DLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMG 5941
+ +WI + ++ +++ +A + LL+ H+ + + D N + GQ L++
Sbjct: 768 EEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKN 827
Query: 5940 IPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLA 5761
+ K++ L+ + S L +R+ ++ F + E+W+ ++E L
Sbjct: 828 NHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLK 887
Query: 5760 NTDLGDSLDSVEHLIKKHEDFEKSLAA-QEEKINALDEFATKLIQGQHYAADDVAEXXXX 5584
D G L SV+ L+ K E F+ L A Q+E I + +L+ +H + +
Sbjct: 888 TDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHAS 947
Query: 5583 XXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTAR------DDSYLDP 5422
R L E+ Q+ R +++ +K S ++ DP
Sbjct: 948 LMKRWTQLLANSATRKKKLLEA---QSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDP 1004
Query: 5421 T------NIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNN 5260
I+ + H F L + + + + QI + + + +
Sbjct: 1005 VRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFTMEALEE 1064
Query: 5259 LWNELVDATNKKGAKL-----REAGNE---QQFNRNIEDVEAWLSE-----LEGQVASED 5119
W L ++ +L R+ N+ Q+F ++ W+ E L+G E+
Sbjct: 1065 TWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRTYLLDGSCMVEE 1124
Query: 5118 YG---KDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQ---------------LAQQFQEE 4993
G L + + ++I + S D +++ LAQQ+ +
Sbjct: 1125 SGTLESQLEATKRKHQEIRAMRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQQWDQL 1184
Query: 4992 EHFNAPVIVRKQENLQQRYNA 4930
+ +R Q NL+Q+ A
Sbjct: 1185 DQLG----MRMQHNLEQQIQA 1201
Score = 107 bits (268), Expect = 3e-21
Identities = 78/312 (25%), Positives = 136/312 (43%), Gaps = 10/312 (3%)
Frame = -1
Query: 7197 DDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENF 7018
++I QR + + H+ K + + RLEE+ ++Q F + +E WI EK+ E++
Sbjct: 726 EEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDY 785
Query: 7017 RDP-SNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALW 6841
D + +Q ++KHEAFE + H + ++ G +I+ N+ E+I +++ L+
Sbjct: 786 GDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKV 845
Query: 6840 XXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKF 6661
+ KL + L F + D + WI EKE + +D G DL V+ L K
Sbjct: 846 SDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQ 905
Query: 6660 DDFLKELGNHQYR-INEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEG 6484
+ F L Q I I D+L+ H + I + + W +L +ATRK+
Sbjct: 906 ETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHASLMKRWTQLLANSATRKKK 965
Query: 6483 LFGAHQVQR--------FNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTER 6328
L A R F + A +W + L+ L ++AL+ H+
Sbjct: 966 LLEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRS 1025
Query: 6327 DLAALEGKMLQL 6292
L++ + QL
Sbjct: 1026 SLSSAQADFNQL 1037
>gi|7512790|pir||T14790 hypothetical protein DKFZp564P0562.1 - human
(fragment)
gi|5817092|emb|CAB53710.1| hypothetical protein [Homo sapiens]
Length = 1325
Score = 1536 bits (3976), Expect = 0.0
Identities = 769/1328 (57%), Positives = 979/1328 (72%), Gaps = 45/1328 (3%)
Frame = -1
Query: 4263 DVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIEPG--TAQQHAQQQVNSIGGKQSEIED 4090
D+LTLLN++N+DWWKVEVNDRQGFVPAAYVK+++P ++++ ++ SI +Q +I++
Sbjct: 1 DILTLLNSTNKDWWKVEVNDRQGFVPAAYVKKLDPAQSASRENLLEEQGSIALRQEQIDN 60
Query: 4089 KYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQK 3910
+Y L+ LGE RK LE++CK + L REAN+L +WI +EA +E+G DLEQVEVLQK
Sbjct: 61 QYHSLLELGEKRKGMLEKSCKKFMLFREANELQQWINEKEAALTSEEVGADLEQVEVLQK 120
Query: 3909 KFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQ------------------- 3787
KFDDF+ DLKANE RL+++N++A L S G V+ QQ
Sbjct: 121 KFDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYGMMPRDETDSKTASP 180
Query: 3786 ----------------IEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQE 3655
I++LN RWR+L LGSAHEVQRFHRD DET++WI+E
Sbjct: 181 WKSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEE 240
Query: 3654 KDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIY 3475
K+ AL+++++G DL SVQALQRKHEG ERDLAALGDK+ SL E A RL QSHPE+AE +
Sbjct: 241 KNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAERLIQSHPESAEDLQ 300
Query: 3474 DLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDV 3295
+ ELN+ W+ L +A+ RK KL DS+D QRFLSD+RDLM WI + LVSS ELA DV
Sbjct: 301 EKCTELNQAWSSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDV 360
Query: 3294 TGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLE 3115
TGAEALLERHQ +RTEID+RA TFQAF+QFG QLL HYA+ +I+ +L +++ R LE
Sbjct: 361 TGAEALLERHQGHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKQKLDILDQERADLE 420
Query: 3114 DAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDP--SGDNVESLIKKHEDFD 2941
AWV RR +LDQCLELQLF+RDCEQA+ WM+AREAFL ED S D+VE+LIKKHEDFD
Sbjct: 421 KAWVQRRMMLDQCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFD 480
Query: 2940 KAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQ 2761
KAIN QEEKI L+ FA+ LI HY ++ +R+++LDRW LK +I+KR KLGESQ
Sbjct: 481 KAINVQEEKIAALQAFADQLIAAGHYAKGDISSRRNEVLDRWRRLKAQMIEKRSKLGESQ 540
Query: 2760 TLQQFSRDADEIENWMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQ 2581
TLQQFSRD DEIE W++EK Q A +E+Y+DPTNIQ KHQK QAFEAELHAN+DRI +I
Sbjct: 541 TLQQFSRDVDEIEAWISEKLQTASDESYKDPTNIQSKHQKHQAFEAELHANADRIRGVID 600
Query: 2580 AGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLE 2401
GN+LIE C G E AV ARL AL DQW LV+ + EKS +LKEANKQ++F +KD +
Sbjct: 601 MGNSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFD 660
Query: 2400 FWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQ 2221
FWL EVE LL SEDYGKDLASV NLLKKH LLEADI AH+DR+ ++N QADSL+ + F
Sbjct: 661 FWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFD 720
Query: 2220 GQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDD 2041
Q+ ++R I R+ +K MA RR KL+++ +HQFFRD+DDEESWIKEKKLLV S+D
Sbjct: 721 TSQVKDKRDTINGRFQKIKSMAASRRAKLNESHRLHQFFRDMDDEESWIKEKKLLVGSED 780
Query: 2040 YGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDL 1861
YGRDL GVQNLR+KH+R++ ELA+HEP + V G++L + + +G+++I++R+
Sbjct: 781 YGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKL---SDDNTIGKEEIQQRLAQF 837
Query: 1860 EQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGL 1681
+ W +++ L R QRL+ES +Q F+ +VEEEEAW+NEK ++ S+++G+ +A +QGL
Sbjct: 838 VEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGL 897
Query: 1680 LKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGR 1501
LKKH+ F+ D +HK RV D+ G LI NHH +I + L ++ ++E A R
Sbjct: 898 LKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKVSDLEKAAAQR 957
Query: 1500 LAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAF 1321
AKL +NSA+LQF WK DVVESWI EKE ++++D+GRDLSSVQ LLTKQE FDAGL AF
Sbjct: 958 KAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAF 1017
Query: 1320 EHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQ 1141
+ EGI IT LKDQL++++H QS AIE RH ++++RW LLA+S AR+ +
Sbjct: 1018 QQEGIANITALKDQLLAAKHVQSKAIEARHASLMKRWSQLLANSAARKKKLLEAQSHFRK 1077
Query: 1140 IEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFR 961
+E+L+L FAKKAS FNSWFENAEEDLTDPVRCNSLEEI+ALR+AH F+ SLSSA+ DF
Sbjct: 1078 VEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFN 1137
Query: 960 QLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRR 781
QL +LDR+IKSF V NPYTWFTM+ALE+TWRNLQ+IIKERE EL +E +RQEENDKLR+
Sbjct: 1138 QLAELDRQIKSFRVASNPYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQ 1197
Query: 780 EFAKLANAFHAWLTNTRQE------MMEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEK 619
EFA+ ANAFH W+ TR M+E GTLE QL+A +RK +EI+A + QL++IE+
Sbjct: 1198 EFAQHANAFHQWIQETRTYLLDGSCMVEESGTLESQLEATKRKHQEIRAMRSQLKKIEDL 1257
Query: 618 GAMLERNLILDNRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREF 439
GA +E LILDN+YTEHSTVG+AQ WDQLDQL MRMQHNLEQQIQARN +GV+EEAL+EF
Sbjct: 1258 GAAMEEALILDNKYTEHSTVGLAQQWDQLDQLGMRMQHNLEQQIQARNTTGVTEEALKEF 1317
Query: 438 SMMFKHFD 415
SMMFKHFD
Sbjct: 1318 SMMFKHFD 1325
Score = 674 bits (1738), Expect = 0.0
Identities = 418/1228 (34%), Positives = 646/1228 (52%), Gaps = 106/1228 (8%)
Frame = -1
Query: 6801 LQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYR 6622
L+++ K R+ +E+ WI EKE +T+E++G DLE VE+LQ+KFDDF K+L ++ R
Sbjct: 76 LEKSCKKFMLFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANESR 135
Query: 6621 INEINQAADKLVEEG-HSEHDQIYKKRD-------------------------------- 6541
+ +IN+ A+ L EG +E Q ++++
Sbjct: 136 LKDINKVAEDLESEGLMAEEVQAVQQQEVYGMMPRDETDSKTASPWKSARLMVHTVATFN 195
Query: 6540 ---DVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLN 6370
++N+ W L LA R + L AH+VQRF+RDADET WI EK+ AL++D+YG DL
Sbjct: 196 SIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLA 255
Query: 6369 NVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKE 6190
+VQALQRKHEG ERDLAAL K+ L + A +L ++HP+ AE + +K + AW++L +
Sbjct: 256 SVQALQRKHEGFERDLAALGDKVNSLGETAERLIQSHPESAEDLQEKCTELNQAWSSLGK 315
Query: 6189 KAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKG 6010
+A RK L S L RFL+D+RDL+SWI ++ ++ +DELAKDV GAEALLE HQ H+
Sbjct: 316 RADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQGHRT 375
Query: 6009 EIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMD 5830
EIDARA +F GQ+L+ G SPE+++KL+ LD E++ L W +RR++ +QC++
Sbjct: 376 EIDARAGTFQAFEQFGQQLLAHGHYASPEIKQKLDILDQERADLEKAWVQRRMMLDQCLE 435
Query: 5829 LQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDE 5650
LQLF+RD EQAE WM +EAFL D GDSLDSVE LIKKHEDF+K++ QEEKI AL
Sbjct: 436 LQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQA 495
Query: 5649 FATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSW 5470
FA +LI HYA D++ + + L ES Q F RD DE+ +W
Sbjct: 496 FADQLIAAGHYAKGDISSRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAW 555
Query: 5469 ITEKLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAA-- 5296
I+EKL TA D+SY DPTNI+ K QKH FE EL AN +R+ + G +I+ G A
Sbjct: 556 ISEKLQTASDESYKDPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSE 615
Query: 5295 DHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDY 5116
D + RL + + W LV + +K KL+EA +Q FN I+D + WLSE+E +ASEDY
Sbjct: 616 DAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDY 675
Query: 5115 GKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRY 4936
GKDL SV NL KK L+E+D +AH DR+ + A F+ + K++ + R+
Sbjct: 676 GKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKDKRDTINGRF 735
Query: 4935 NALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQ 4756
++ R+ KL ESH+ +Q FRD++DE +WI+EK+ + GS + GRDL GVQNL KK
Sbjct: 736 QKIKSMAASRRAKLNESHRLHQFFRDMDDEESWIKEKKLLVGSEDYGRDLTGVQNLRKKH 795
Query: 4755 QALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDL 4576
+ L AE+A H+ I+ V + EI+ +LAQ ++W+ LK A R L
Sbjct: 796 KRLEAELAAHEPAIQGVLDTGKKLSDDNTIGKEEIQQRLAQFVEHWKELKQLAAARGQRL 855
Query: 4575 DDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSD-------- 4420
++SL+ Q++++ E +AW++EK +V S DYG + + LLKKH A +D
Sbjct: 856 EESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRV 915
Query: 4419 ------------------------LEAFKGTIEDLRKQASQCKYQEQPMGQLGRDCVLAL 4312
++ G + DL K A+Q K +L +
Sbjct: 916 NDVCTNGQDLIKKNNHHEENISSKMKGLNGKVSDLEKAAAQRK------AKLDENSAFLQ 969
Query: 4311 YDYQEK------SPREVSMKKGD-------VLTLLNASNRDWWKVEVNDRQGFVPAAYVK 4171
++++ +E S+K D V TLL ++ ++G +K
Sbjct: 970 FNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALK 1029
Query: 4170 RIEPGTAQQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQ--------L 4015
+ A +H Q + +I + + + ++ +L+ RK+KL EA ++
Sbjct: 1030 --DQLLAAKHVQSK--AIEARHASLMKRWSQLLANSAARKKKLLEAQSHFRKVEDLFLTF 1085
Query: 4014 LREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATA 3835
++A+ W ++ E LE+++ L++ D F+ L + + ++ ++
Sbjct: 1086 AKKASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQ 1145
Query: 3834 LTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGS---------------AHEVQ 3700
+ S + + +E L WR L +L A
Sbjct: 1146 IKSF-RVASNPYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHAN 1204
Query: 3699 RFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKA 3520
FH+ + ETR ++ D + E+ G ++A +RKH+ ++ A+ ++K +++
Sbjct: 1205 AFHQWIQETRTYL--LDGSCMVEESGTLESQLEATKRKHQ----EIRAMRSQLKKIEDLG 1258
Query: 3519 NRLRQSHPEAAEQIYDLQRELNEQWNRL 3436
+ ++ + L +QW++L
Sbjct: 1259 AAMEEALILDNKYTEHSTVGLAQQWDQL 1286
Score = 335 bits (860), Expect = 7e-90
Identities = 246/939 (26%), Positives = 422/939 (44%), Gaps = 14/939 (1%)
Frame = -1
Query: 7137 SQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENF-RDPSNLQAKIQKHEAFEAE 6961
++ + L A + Q F RDADE WI EK Q +N+ D +++QA +KHE FE +
Sbjct: 211 AEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERD 270
Query: 6960 VQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKL 6781
+ A + +L +T +IQ + ++E ++++ EL+ W + KL + L
Sbjct: 271 LAALGDKVNSLGETAERLIQSHPESAEDLQEKCTELNQAWSSLGKRADQRKAKLGDSHDL 330
Query: 6780 LHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQA 6601
F+ +++ WI V+++++ D+ E L + E+ Q
Sbjct: 331 QRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQGHRTEIDARAGTFQAFEQF 390
Query: 6600 ADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWI 6421
+L+ GH +I +K D ++ L R+ L ++Q F+RD ++ W+
Sbjct: 391 GQQLLAHGHYASPEIKQKLDILDQERADLEKAWVQRRMMLDQCLELQLFHRDCEQAENWM 450
Query: 6420 GEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEA 6241
++ L+++D G L++V+AL +KHE ++ + E K+ L+ A +L
Sbjct: 451 AAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAAGHYAKGD 510
Query: 6240 IHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAK 6061
I + ++ W LK + ++ L S L +F D ++ +WI + K +DE K
Sbjct: 511 ISSRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISE-KLQTASDESYK 569
Query: 6060 DVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPE--VQEKLEKLDHEK 5887
D ++ + HQ + E+ A AD G L+E G E V+ +L L +
Sbjct: 570 DPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQW 629
Query: 5886 SSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKH 5707
L+ E+ ++ Q F + + W+++ EA LA+ D G L SV +L+KKH
Sbjct: 630 QFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKH 689
Query: 5706 EDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNAL 5527
+ E ++A E+++ L+ A L+ + V + R L
Sbjct: 690 QLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKDKRDTINGRFQKIKSMAASRRAKL 749
Query: 5526 KESYKRQTFDRDCDEMVSWITE-KLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRL 5350
ES++ F RD D+ SWI E KL +D D T ++ +KH E EL A+E +
Sbjct: 750 NESHRLHQFFRDMDDEESWIKEKKLLVGSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAI 809
Query: 5349 DDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIE 5170
+ TG+++ D + I RL Q W EL +G +L E+ QQF N+E
Sbjct: 810 QGVLDTGKKLSDDNTIGKEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVE 869
Query: 5169 DVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEE 4990
+ EAW++E VASEDYG L ++Q L KK E+DF H DRV+ + Q ++
Sbjct: 870 EEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKN 929
Query: 4989 HFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAG 4810
+ + I K + L + + L +RK KL E+ Q + +WI EKE
Sbjct: 930 NHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLK 989
Query: 4809 STNRGRDLIGVQNLIKKQQALIAEI-ANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQ 4633
+ + GRDL VQ L+ KQ+ A + A I ++++ + ++ H + I + A
Sbjct: 990 TDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHVQSKAIEARHAS 1049
Query: 4632 LRDNWRILKSKAEKRRTDLDDSLQAH------QYLSDANEADA---WMSEKEPIVGSTDY 4480
L W L + + R+ L ++ Q+H +L+ A +A A W E +
Sbjct: 1050 LMKRWSQLLANSAARKKKLLEA-QSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVR 1108
Query: 4479 GKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCK 4363
+ +AL + H A S L + + L + Q K
Sbjct: 1109 CNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIK 1147
Score = 315 bits (808), Expect = 8e-84
Identities = 288/1299 (22%), Positives = 557/1299 (42%), Gaps = 121/1299 (9%)
Frame = -1
Query: 5979 QTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQ 5800
Q+AS L E G + + E++D++ SLL L E+R+ + E+ + +R+ +
Sbjct: 37 QSASRENLLEEQG-----SIALRQEQIDNQYHSLLELGEKRKGMLEKSCKKFMLFREANE 91
Query: 5799 AETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKL----- 5635
+ W+N++EA L + ++G L+ VE L KK +DF+K L A E ++ +++ A L
Sbjct: 92 LQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGL 151
Query: 5634 -------IQGQH---YAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKR-------- 5509
+Q Q D + N++KE +R
Sbjct: 152 MAEEVQAVQQQEVYGMMPRDETDSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLA 211
Query: 5508 -------------QTFDRDCDEMVSWITEKLSTARDDSY-LDPTNIRGKLQKHINFEQEL 5371
Q F RD DE WI EK D+Y D +++ +KH FE++L
Sbjct: 212 EERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDL 271
Query: 5370 KANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQ 5191
A ++++ + T E++I S +A+ + ++ ++N W+ L +++ AKL ++ + Q
Sbjct: 272 AALGDKVNSLGETAERLIQSHPESAEDLQEKCTELNQAWSSLGKRADQRKAKLGDSHDLQ 331
Query: 5190 QFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLA 5011
+F + D+ +W++ + G V+S++ KD+ + L ++ ++ +A +Q
Sbjct: 332 RFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQGHRTEIDARAGTFQAFEQFG 391
Query: 5010 QQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIR 4831
QQ H+ +P I +K + L Q L +R+ L + + RD E W+
Sbjct: 392 QQLLAHGHYASPEIKQKLDILDQERADLEKAWVQRRMMLDQCLELQLFHRDCEQAENWMA 451
Query: 4830 EKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEI 4651
+E + ++G L V+ LIKK + I + +I ++ + A+ +I GH+ +I
Sbjct: 452 AREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAAGHYAKGDI 511
Query: 4650 RDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKD 4471
+ ++ D WR LK++ ++R+ L +S Q+ D +E +AW+SEK Y KD
Sbjct: 512 SSRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESY-KD 570
Query: 4470 EDSAEALLKKHRALLSDLEA----FKGTIE---DLRKQASQCKYQEQPMGQLGRDCVLAL 4312
+ ++ +KH+A ++L A +G I+ L ++ + ++ +L
Sbjct: 571 PTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQ 630
Query: 4311 YDYQEKSPREVSMKKGDVLTLLNASNR--DWWKVEVN-------------------DRQG 4195
+ Q+ + + +K+ + N + D+W EV +
Sbjct: 631 FLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQ 690
Query: 4194 FVPA---AYVKRIEPGTAQQHAQQ-----QVNSIGGKQSEIEDKYQRLMMLGETRKRKLE 4039
+ A A+ R++ +Q + + + K+ I ++Q++ + +R+ KL
Sbjct: 691 LLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKDKRDTINGRFQKIKSMAASRRAKLN 750
Query: 4038 EACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQ 3859
E+ + +Q R+ +D WIK ++ + ++ G DL V+ L+KK + +L A+E +Q
Sbjct: 751 ESHRLHQFFRDMDDEESWIKEKKLLVGSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQ 810
Query: 3858 EMNQIATALT---SVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHR 3688
+ L+ ++G+ E R+ Q +E W+ L +L + E Q+F
Sbjct: 811 GVLDTGKKLSDDNTIGKEEIQQRLAQFVE----HWKELKQLAAARGQRLEESLEYQQFVA 866
Query: 3687 DVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLR 3508
+V+E WI EK + SED+G L ++Q L +KHE E D D++ + L
Sbjct: 867 NVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLI 926
Query: 3507 QSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQ 3328
+ + E I + LN + + L A RK KL ++ + +F + WI
Sbjct: 927 KKNNHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKEN 986
Query: 3327 LVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFG--------NQLLNSHHYA 3172
+ + + D++ + LL + + + A QAF Q G +QLL + H
Sbjct: 987 SLKTDDYGRDLSSVQTLLTKQETF-------DAGLQAFQQEGIANITALKDQLLAAKHVQ 1039
Query: 3171 AGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQA-----------DTWM 3025
+ IE R + + L AR+ L LE Q +R E ++W
Sbjct: 1040 SKAIEARHASLMKRWSQLLANSAARKKKL---LEAQSHFRKVEDLFLTFAKKASAFNSWF 1096
Query: 3024 SAREAFLAQEDP----SGDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDS 2857
E L DP S + +++L + H+ F ++++ + L + +
Sbjct: 1097 ENAEEDLT--DPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASN 1154
Query: 2856 PAVTRKRDQILDRWNGLKEALIQKRFKLGESQ--------TLQQFSRDADEIENWMTEKF 2701
P + + + W L++ + ++ +L + Q Q+F++ A+ W+ E
Sbjct: 1155 PYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETR 1214
Query: 2700 QIAQE-----------ENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQA---GNNLI 2563
+ E+ + T ++KHQ+ +A ++L D AA+ +A N
Sbjct: 1215 TYLLDGSCMVEESGTLESQLEAT--KRKHQEIRAMRSQLKKIEDLGAAMEEALILDNKYT 1272
Query: 2562 ENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKE 2446
E++ G L QWD L + + L++
Sbjct: 1273 EHSTVG------------LAQQWDQLDQLGMRMQHNLEQ 1299
Score = 280 bits (717), Expect = 3e-73
Identities = 205/801 (25%), Positives = 358/801 (44%), Gaps = 46/801 (5%)
Frame = -1
Query: 7194 DIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENFR 7015
DI RR EVL + K KR +L E++ Q F RD DE+ WI EKLQTA +E+++
Sbjct: 510 DISSRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYK 569
Query: 7014 DPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEH--IKKRLEELHALW 6841
DP+N+Q+K QKH+AFEAE+ A+A I + GN++I+ A +K RL L W
Sbjct: 570 DPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQW 629
Query: 6840 XXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKF 6661
K KL++A K +F + +W+ E E + +ED G DL V L +K
Sbjct: 630 QFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKH 689
Query: 6660 DDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGL 6481
++ H+ R+ ++N AD L+ + Q+ KRD +N + ++ ++AA+R+ L
Sbjct: 690 QLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKDKRDTINGRFQKIKSMAASRRAKL 749
Query: 6480 FGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKM 6301
+H++ +F RD D+ +WI EK L + S+DYGRDL VQ L++KH+ E +LAA E +
Sbjct: 750 NESHRLHQFFRDMDDEESWIKEKKLLVGSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAI 809
Query: 6300 LQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYR 6121
+ KL++ + E I Q+ W LK+ A R LE S + +F+A+
Sbjct: 810 QGVLDTGKKLSDDNTIGKEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVE 869
Query: 6120 DLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMG 5941
+ +WI + ++ +++ +A + LL+ H+ + + D N + GQ L++
Sbjct: 870 EEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKN 929
Query: 5940 IPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLA 5761
+ K++ L+ + S L +R+ ++ F + E+W+ ++E L
Sbjct: 930 NHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLK 989
Query: 5760 NTDLGDSLDSVEHLIKKHEDFEKSLAA-QEEKINALDEFATKLIQGQHYAADDVAEXXXX 5584
D G L SV+ L+ K E F+ L A Q+E I + +L+ +H + +
Sbjct: 990 TDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHVQSKAIEARHAS 1049
Query: 5583 XXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTAR------DDSYLDP 5422
R L E+ Q+ R +++ +K S ++ DP
Sbjct: 1050 LMKRWSQLLANSAARKKKLLEA---QSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDP 1106
Query: 5421 T------NIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNN 5260
I+ + H F L + + + + QI + + + +
Sbjct: 1107 VRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFTMEALEE 1166
Query: 5259 LWNELVDATNKKGAKL-----REAGNE---QQFNRNIEDVEAWLSE-----LEGQVASED 5119
W L ++ +L R+ N+ Q+F ++ W+ E L+G E+
Sbjct: 1167 TWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRTYLLDGSCMVEE 1226
Query: 5118 YG---KDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQ---------------LAQQFQEE 4993
G L + + ++I + S D +++ LAQQ+ +
Sbjct: 1227 SGTLESQLEATKRKHQEIRAMRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQQWDQL 1286
Query: 4992 EHFNAPVIVRKQENLQQRYNA 4930
+ +R Q NL+Q+ A
Sbjct: 1287 DQLG----MRMQHNLEQQIQA 1303
Score = 106 bits (264), Expect = 1e-20
Identities = 77/312 (24%), Positives = 135/312 (42%), Gaps = 10/312 (3%)
Frame = -1
Query: 7197 DDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENF 7018
++I QR + + H+ K + + RLEE+ ++Q F + +E WI EK+ E++
Sbjct: 828 EEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDY 887
Query: 7017 RDP-SNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALW 6841
D + +Q ++KHEAFE + H + ++ G +I+ N+ E+I +++ L+
Sbjct: 888 GDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKV 947
Query: 6840 XXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKF 6661
+ KL + L F + D + WI EKE + +D G DL V+ L K
Sbjct: 948 SDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQ 1007
Query: 6660 DDFLKELGNHQYR-INEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEG 6484
+ F L Q I I D+L+ H + I + + W +L +A RK+
Sbjct: 1008 ETFDAGLQAFQQEGIANITALKDQLLAAKHVQSKAIEARHASLMKRWSQLLANSAARKKK 1067
Query: 6483 LFGAHQVQR--------FNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTER 6328
L A R F + A +W + L+ L ++AL+ H+
Sbjct: 1068 LLEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRS 1127
Query: 6327 DLAALEGKMLQL 6292
L++ + QL
Sbjct: 1128 SLSSAQADFNQL 1139
>gi|92758|pir||A32612 spectrin alpha chain, nonerythroid - rat
(fragment)
gi|203014|gb|AAA40770.1| nonerythroid alpha-spectrin
Length = 1030
Score = 1220 bits (3156), Expect = 0.0
Identities = 608/1021 (59%), Positives = 764/1021 (74%), Gaps = 8/1021 (0%)
Frame = -1
Query: 3534 LDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDL 3355
L E A RL QSHPE+AE + + ELN+ W L +A RK KL DS+D QRFLSD+RDL
Sbjct: 1 LGETAQRLIQSHPESAEDLKEKCTELNQAWTSLGKRAYQRKAKLGDSHDLQRFLSDFRDL 60
Query: 3354 MQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHY 3175
M WI + LVSS ELA DVTGAEALLERHQE+RTEID+RA TFQAF+QFG QLL HY
Sbjct: 61 MSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHY 120
Query: 3174 AAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQE 2995
A+ +I+ +L +++ R LE AWV RR +LD CLELQLF+RDCEQA+ WM+AREAFL E
Sbjct: 121 ASPEIKEKLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTE 180
Query: 2994 DP--SGDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILD 2821
D S D+VE+LIKKHEDFDKAIN QEEKI L+ FA+ LI +HY + +R+++LD
Sbjct: 181 DKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAVDHYAKGDIANRRNEVLD 240
Query: 2820 RWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNIQQKHQK 2641
RW LK +I+KR KLGESQTLQQFSRD DEIE W++EK Q A +E+Y+DPTNIQ KHQK
Sbjct: 241 RWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPTNIQSKHQK 300
Query: 2640 QQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKS 2461
QAFEAELHAN+DRI +I GN+LIE C G E AV ARL AL DQW LV+ + EKS
Sbjct: 301 HQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKS 360
Query: 2460 YRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQ 2281
+LKEANKQ++F +KD +FWL EVE LL SEDYGKDLASV NLLKKH LEADI AH+
Sbjct: 361 QKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQALEADISAHE 420
Query: 2280 DRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFR 2101
DR+ ++N QADSL+ + F Q+ E+R I R+ +K MAT RR KLS++ +HQFFR
Sbjct: 421 DRLKDLNSQADSLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKLSESHRLHQFFR 480
Query: 2100 DIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELL 1921
D+DDEESWIKEKKLLVSS+DYGRDL GVQNLR+KH+R++ ELA+HEP + V G++L
Sbjct: 481 DMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKL- 539
Query: 1920 RSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNE 1741
+ + +G+++I++R+ + W +++ L R QRL+ES +Q F+ +VEEEEAW+NE
Sbjct: 540 --SDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINE 597
Query: 1740 KQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIK 1561
K ++ S+++G+ +A +QGLLKKH+ F+ D +HK RV D+ G LI NHH +I
Sbjct: 598 KMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENIS 657
Query: 1560 QRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDL 1381
+ L ++ ++E A R AKL +NSA+LQF WK DVVESWI EKE ++++D+GRDL
Sbjct: 658 SKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDL 717
Query: 1380 SSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNL 1201
SSVQ LLTKQE FDAGL AF+ EGI IT LKDQL++++H QS AIE RH ++++RW L
Sbjct: 718 SSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHASLMKRWTQL 777
Query: 1200 LAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRA 1021
LA+S R+ ++E+L+L FAKKAS FNSWFENAEEDLTDPVRCNSLEEI+A
Sbjct: 778 LANSATRKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEIKA 837
Query: 1020 LRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKE 841
LR+AH F+ SLSSA+ DF QL +LDR+IKSF V NPYTWFTM+ALE+TWRNLQ+IIKE
Sbjct: 838 LREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFTMEALEETWRNLQKIIKE 897
Query: 840 REQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQE------MMEAGGTLEEQLDAV 679
RE EL +E +RQEENDKLR+EFA+ ANAFH W+ TR M+E GTLE QL+A
Sbjct: 898 RELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRTYLLDGSCMVEESGTLESQLEAT 957
Query: 678 ERKAKEIKANKGQLRQIEEKGAMLERNLILDNRYTEHSTVGIAQAWDQLDQLAMRMQHNL 499
+RK +EI+A + QL++IE+ GA +E LILDN+YTEHSTVG+AQ WDQLDQL MRMQHNL
Sbjct: 958 KRKHQEIRAMRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQQWDQLDQLGMRMQHNL 1017
Query: 498 E 496
E
Sbjct: 1018 E 1018
Score = 531 bits (1368), Expect = e-149
Identities = 336/1023 (32%), Positives = 525/1023 (50%), Gaps = 70/1023 (6%)
Frame = -1
Query: 6294 LEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDL 6115
L + A +L ++HP+ AE + +K + AW +L ++A RK L S L RFL+D+RDL
Sbjct: 1 LGETAQRLIQSHPESAEDLKEKCTELNQAWTSLGKRAYQRKAKLGDSHDLQRFLSDFRDL 60
Query: 6114 ISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIP 5935
+SWI ++ ++ +DELAKDV GAEALLE HQEH+ EIDARA +F GQ+L+ G
Sbjct: 61 MSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHY 120
Query: 5934 ESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANT 5755
SPE++EKL+ LD E++ L W +RR++ + C++LQLF+RD EQAE WM +EAFL
Sbjct: 121 ASPEIKEKLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTE 180
Query: 5754 DLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXX 5575
D GDSLDSVE LIKKHEDF+K++ QEEKI AL FA +LI HYA D+A
Sbjct: 181 DKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAVDHYAKGDIANRRNEVLD 240
Query: 5574 XXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGKLQK 5395
+ + L ES Q F RD DE+ +WI+EKL TA D+SY DPTNI+ K QK
Sbjct: 241 RWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPTNIQSKHQK 300
Query: 5394 HINFEQELKANENRLDDIRSTGEQIIDSGHFAA--DHIGDRLRQVNNLWNELVDATNKKG 5221
H FE EL AN +R+ + G +I+ G A D + RL + + W LV + +K
Sbjct: 301 HQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKS 360
Query: 5220 AKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHN 5041
KL+EA +Q FN I+D + WLSE+E +ASEDYGKDL SV NL KK +E+D +AH
Sbjct: 361 QKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQALEADISAHE 420
Query: 5040 DRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFR 4861
DR+ + A F+ + K++ + R+ ++ R+ KL ESH+ +Q FR
Sbjct: 421 DRLKDLNSQADSLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKLSESHRLHQFFR 480
Query: 4860 DIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMI 4681
D++DE +WI+EK+ + S + GRDL GVQNL KK + L AE+A H+ I+ V +
Sbjct: 481 DMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLS 540
Query: 4680 QQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEP 4501
EI+ +LAQ ++W+ LK A R L++SL+ Q++++ E +AW++EK
Sbjct: 541 DDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMT 600
Query: 4500 IVGSTDYGKDEDSAEALLKKHRALLSD--------------------------------L 4417
+V S DYG + + LLKKH A +D +
Sbjct: 601 LVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKM 660
Query: 4416 EAFKGTIEDLRKQASQCKYQEQPMGQLGRDCVLALYDYQEK------SPREVSMKKGD-- 4261
+ G + DL K A+Q K +L + ++++ +E S+K D
Sbjct: 661 KGLNGKVSDLEKAAAQRK------AKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYG 714
Query: 4260 -----VLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIEPGTAQQHAQQQVNSIGGKQSEI 4096
V TLL ++ ++G +K + A +H Q + +I + + +
Sbjct: 715 RDLSSVQTLLTKQETFDAGLQAFQQEGIANITALK--DQLLAAKHIQSK--AIEARHASL 770
Query: 4095 EDKYQRLMMLGETRKRKLEEACKGYQ--------LLREANDLAEWIKSREAVAAQQEIGT 3940
++ +L+ TRK+KL EA ++ ++A+ W ++ E
Sbjct: 771 MKRWTQLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCN 830
Query: 3939 DLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWR 3760
LE+++ L++ D F+ L + + ++ ++ + S + + +E L WR
Sbjct: 831 SLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSF-RVASNPYTWFTMEALEETWR 889
Query: 3759 ALXXXXXXXXXQLGS---------------AHEVQRFHRDVDETRDWIQEKDDALDSEDF 3625
L +L A FH+ + ETR ++ D + E+
Sbjct: 890 NLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRTYL--LDGSCMVEES 947
Query: 3624 GRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQW 3445
G ++A +RKH+ ++ A+ ++K +++ + ++ + L +QW
Sbjct: 948 GTLESQLEATKRKHQ----EIRAMRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQQW 1003
Query: 3444 NRL 3436
++L
Sbjct: 1004 DQL 1006
Score = 362 bits (928), Expect = 1e-97
Identities = 243/1026 (23%), Positives = 481/1026 (46%), Gaps = 20/1026 (1%)
Frame = -1
Query: 3813 ETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDS 3634
E+A ++++ +LN W +L +LG +H++QRF D + WI + S
Sbjct: 14 ESAEDLKEKCTELNQAWTSLGKRAYQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSS 73
Query: 3633 EDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELN 3454
++ +D+ +AL +H+ ++ A ++ ++ +L A+ +I + L+
Sbjct: 74 DELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKEKLDILD 133
Query: 3453 EQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALL 3274
++ L R+ L + Q F D W+A+ +++++ + + EAL+
Sbjct: 134 QERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALI 193
Query: 3273 ERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARR 3094
++H+++ I+ + A F +QL+ HYA GDI NR V + + L+ + +R
Sbjct: 194 KKHEDFDKAINVQEEKIAALQAFADQLIAVDHYAKGDIANRRNEVLDRWRRLKAQMIEKR 253
Query: 3093 NILDQCLELQLFYRDCEQADTWMSAREAFLAQE---DPSGDNVESLIKKHEDFDKAINTQ 2923
+ L + LQ F RD ++ + W+S + + E DP+ N++S +KH+ F+ ++
Sbjct: 254 SKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPT--NIQSKHQKHQAFEAELHAN 311
Query: 2922 EEKIKGLKLFAESLIKNNHY--DSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQ 2749
++I+G+ SLI+ AV + + D+W L + +K KL E+ Q
Sbjct: 312 ADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQN 371
Query: 2748 FSRDADEIENWMTEKFQIAQEENY-RDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGN 2572
F+ + + W++E + E+Y +D ++ +K QA EA++ A+ DR+ + +
Sbjct: 372 FNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQALEADISAHEDRLKDLNSQAD 431
Query: 2571 NLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWL 2392
+L+ ++ + V + +N ++ + T + +L E+++ F + D E W+
Sbjct: 432 SLMTSSAFDTSQ--VKEKRDTINGRFQKIKSMATSRRAKLSESHRLHQFFRDMDDEESWI 489
Query: 2391 GEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQ 2212
E ++L+ SEDYG+DL V+NL KKH LEA++ AH+ + + + L +++ ++
Sbjct: 490 KEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGQEE 549
Query: 2211 IAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGR 2032
I +R + + +K++A R +L ++L QF ++++EE+WI EK LV+S+DYG
Sbjct: 550 IQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGD 609
Query: 2031 DLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQS 1852
L +Q L +KH +T+ H+ +V+ V G++L++ + E+ I +M+ L
Sbjct: 610 TLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIK---KNNHHEENISSKMKGLNGK 666
Query: 1851 WGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKK 1672
+ R +LDE+ AF F + E+W+ EK+ L +D++G +++ VQ LL K
Sbjct: 667 VSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTK 726
Query: 1671 HDTFQVDLELHKQR-VADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLA 1495
+TF L+ +Q +A++ D L+ + + I+ R L R ++ + + R
Sbjct: 727 QETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHASLMKRWTQLLANSATRKK 786
Query: 1494 KLRD--------NSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFD 1339
KL + +L F K SW E+ + L ++ L +AF
Sbjct: 787 KLLEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFR 846
Query: 1338 AGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXX 1159
+ L++ + + ++ EL Q+ S +P + + W+NL + R
Sbjct: 847 SSLSSAQAD-FNQLAELDRQIKSFRVASNPYTWFTMEALEETWRNLQKIIKERELELQKE 905
Query: 1158 XXXXXQIEELYLAFAKKASTFNSWFENAEEDLTD----PVRCNSLE-EIRALRDAHGEFQ 994
+ ++L FA+ A+ F+ W + L D +LE ++ A + H E
Sbjct: 906 QRRQEENDKLRQEFAQHANAFHQWIQETRTYLLDGSCMVEESGTLESQLEATKRKHQE-- 963
Query: 993 RSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREH 814
+ + ++++DL ++ + N YT + L W L ++ + L
Sbjct: 964 --IRAMRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQQWDQLDQLGMRMQHNLEHAD 1021
Query: 813 QRQEEN 796
QE N
Sbjct: 1022 PGQEHN 1027
Score = 330 bits (847), Expect = 2e-88
Identities = 246/1007 (24%), Positives = 455/1007 (44%), Gaps = 35/1007 (3%)
Frame = -1
Query: 7206 ETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILE-KLQTAQ 7030
E+A+D+ ++ E+ ++ + ++ +L ++ Q F D +L WI + +
Sbjct: 14 ESAEDLKEKCTELNQAWTSLGKRAYQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSS 73
Query: 7029 EENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELH 6850
+E +D + +A +++H+ E+ A A T ++ G ++ H H+AS IK++L+ L
Sbjct: 74 DELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKEKLDILD 133
Query: 6849 ALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQ 6670
+ + L L+L F R C++ W+ +E ++ ED G L+ VE L
Sbjct: 134 QERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALI 193
Query: 6669 RKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRK 6490
+K +DF K + + +I + AD+L+ H I +R++V D W RL ++
Sbjct: 194 KKHEDFDKAINVQEEKIAALQAFADQLIAVDHYAKGDIANRRNEVLDRWRRLKAQMIEKR 253
Query: 6489 EGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALE 6310
L + +Q+F+RD DE AWI EK L +SD+ +D N+Q+ +KH+ E +L A
Sbjct: 254 SKLGESQTLQQFSRDVDEIEAWISEK-LQTASDESYKDPTNIQSKHQKHQAFEAELHANA 312
Query: 6309 GKMLQLEKEAHKLAE--THPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRF 6136
++ + + L E +A+ + W L +K+ + L+ + + F
Sbjct: 313 DRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNF 372
Query: 6135 LADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQK 5956
+D W+ +++A++ +++ KD+A LL+ HQ + +I A D S
Sbjct: 373 NTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQALEADISAHEDRLKDLNSQADS 432
Query: 5955 LVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQ 5776
L+ ++ +V+EK + ++ + + RR + L F+RD + E+W+ ++
Sbjct: 433 LMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKLSESHRLHQFFRDMDDEESWIKEK 492
Query: 5775 EAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAE 5596
+ +++ D G L V++L KKH+ E LAA E I + + KL +++ +
Sbjct: 493 KLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGQEEIQQ 552
Query: 5595 XXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDP-T 5419
RG L+ES + Q F + +E +WI EK++ + Y D
Sbjct: 553 RLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLA 612
Query: 5418 NIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVD 5239
I+G L+KH FE + +++R++D+ + G+ +I + ++I +++ +N ++L
Sbjct: 613 AIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKVSDLEK 672
Query: 5238 ATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIES 5059
A ++ AKL E QFN + VE+W+ E E + ++DYG+DL SVQ L K ++
Sbjct: 673 AAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDA 732
Query: 5058 DFNA-HNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESH 4882
A + + I L Q +H + I + +L +R+ L RK+KL E+
Sbjct: 733 GLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHASLMKRWTQLLANSATRKKKLLEAQ 792
Query: 4881 QGNQLFRDIEDEL-----------AWIREKEQVAGSTNRGRDLIGVQNL----------I 4765
FR +ED +W E+ R L ++ L +
Sbjct: 793 SH---FRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSL 849
Query: 4764 KKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKS------ 4603
QA ++A D QI+S A+N P + L + WR L+
Sbjct: 850 SSAQADFNQLAELDRQIKSFRVASN----------PYTWFTMEALEETWRNLQKIIKERE 899
Query: 4602 ---KAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRA 4432
+ E+RR + +D L+ ++ AN W+ E + Y D ++++
Sbjct: 900 LELQKEQRRQEENDKLR-QEFAQHANAFHQWIQE------TRTYLLD---GSCMVEESGT 949
Query: 4431 LLSDLEAFKGTIEDLRKQASQCKYQEQPMGQLGRDCVLALYDYQEKS 4291
L S LEA K +++R SQ K E +G + ++ Y E S
Sbjct: 950 LESQLEATKRKHQEIRAMRSQLKKIED-LGAAMEEALILDNKYTEHS 995
Score = 302 bits (773), Expect = 9e-80
Identities = 226/870 (25%), Positives = 391/870 (43%), Gaps = 14/870 (1%)
Frame = -1
Query: 6930 LDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEI 6751
L +T +IQ + ++E +K++ EL+ W + KL + L F+ ++
Sbjct: 1 LGETAQRLIQSHPESAEDLKEKCTELNQAWTSLGKRAYQRKAKLGDSHDLQRFLSDFRDL 60
Query: 6750 LYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHS 6571
+ WI V+++++ D+ E L + + E+ Q +L+ GH
Sbjct: 61 MSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHY 120
Query: 6570 EHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSD 6391
+I +K D ++ L R+ L ++Q F+RD ++ W+ ++ L+++
Sbjct: 121 ASPEIKEKLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTE 180
Query: 6390 DYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKL-AETHPDRAEAIHQKNDDTK 6214
D G L++V+AL +KHE ++ + E K+ L+ A +L A H + + +++N +
Sbjct: 181 DKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAVDHYAKGDIANRRN-EVL 239
Query: 6213 AAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALL 6034
W LK + ++ L S L +F D ++ +WI + K +DE KD ++
Sbjct: 240 DRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISE-KLQTASDESYKDPTNIQSKH 298
Query: 6033 ESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPE--VQEKLEKLDHEKSSLLGLWEE 5860
+ HQ + E+ A AD G L+E G E V+ +L L + L+ E
Sbjct: 299 QKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQFLVQKSAE 358
Query: 5859 RRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAA 5680
+ ++ Q F + + W+++ EA LA+ D G L SV +L+KKH+ E ++A
Sbjct: 359 KSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQALEADISA 418
Query: 5679 QEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTF 5500
E+++ L+ A L+ + V E R L ES++ F
Sbjct: 419 HEDRLKDLNSQADSLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKLSESHRLHQF 478
Query: 5499 DRDCDEMVSWITE-KLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQ 5323
RD D+ SWI E KL + +D D T ++ +KH E EL A+E + + TG++
Sbjct: 479 FRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKK 538
Query: 5322 IIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSEL 5143
+ D + I RL Q W EL +G +L E+ QQF N+E+ EAW++E
Sbjct: 539 LSDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEK 598
Query: 5142 EGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVR 4963
VASEDYG L ++Q L KK E+DF H DRV+ + Q ++ + + I
Sbjct: 599 MTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISS 658
Query: 4962 KQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLI 4783
K + L + + L +RK KL E+ Q + +WI EKE + + GRDL
Sbjct: 659 KMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLS 718
Query: 4782 GVQNLIKKQQALIAEI-ANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILK 4606
VQ L+ KQ+ A + A I ++++ + ++ H + I + A L W L
Sbjct: 719 SVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHASLMKRWTQLL 778
Query: 4605 SKAEKRRTDLDDSLQAH------QYLSDANEADA---WMSEKEPIVGSTDYGKDEDSAEA 4453
+ + R+ L ++ Q+H +L+ A +A A W E + + +A
Sbjct: 779 ANSATRKKKLLEA-QSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEIKA 837
Query: 4452 LLKKHRALLSDLEAFKGTIEDLRKQASQCK 4363
L + H A S L + + L + Q K
Sbjct: 838 LREAHDAFRSSLSSAQADFNQLAELDRQIK 867
Score = 266 bits (680), Expect = 6e-69
Identities = 240/1043 (23%), Positives = 462/1043 (44%), Gaps = 69/1043 (6%)
Frame = -1
Query: 4707 VSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEA 4528
+ A +IQ A ++++K +L W L +A +R+ L DS ++LSD +
Sbjct: 1 LGETAQRLIQSHPESAEDLKEKCTELNQAWTSLGKRAYQRKAKLGDSHDLQRFLSDFRDL 60
Query: 4527 DAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQC------ 4366
+W++ +V S + KD AEALL++H+ ++++A GT + + Q
Sbjct: 61 MSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHY 120
Query: 4365 --------------------KYQEQPMGQLGRDCVLALYDYQ-EKSPREVSMKKGDVLTL 4249
K Q L L L+ E++ ++ ++ + T
Sbjct: 121 ASPEIKEKLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTE 180
Query: 4248 LNASNRDWWKVEVNDRQGFVPAAYVKRIEPGTAQQHAQQQV-------NSIGGKQSEIED 4090
+ D + + + F A V+ + Q A Q + I +++E+ D
Sbjct: 181 DKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAVDHYAKGDIANRRNEVLD 240
Query: 4089 KYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQK 3910
+++RL ++ KL E+ Q R+ +++ WI S + A E D ++ +
Sbjct: 241 RWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWI-SEKLQTASDESYKDPTNIQSKHQ 299
Query: 3909 KFDDFKGDLKANEVRLQEMNQIATALTSVGQ---TETAVRIRQQIEDLNARWRALXXXXX 3739
K F+ +L AN R++ + + +L G +E AV+ R + L +W+ L
Sbjct: 300 KHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKAR--LAALADQWQFLVQKSA 357
Query: 3738 XXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLA 3559
+L A++ Q F+ + + W+ E + L SED+G+DL SV L +KH+ +E D++
Sbjct: 358 EKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQALEADIS 417
Query: 3558 ALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQR 3379
A D++K L+ +A+ L S Q+ + + +N ++ ++ S A +R+ KL +S+ +
Sbjct: 418 AHEDRLKDLNSQADSLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKLSESHRLHQ 477
Query: 3378 FLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGN 3199
F D D WI LVSS++ D+TG + L ++H+ E+ + Q G
Sbjct: 478 FFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGK 537
Query: 3198 QLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSA 3019
+L + + +I+ RL E K L+ AR L++ LE Q F + E+ + W++
Sbjct: 538 KLSDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINE 597
Query: 3018 REAFLAQEDPSGDN---VESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAV 2848
+ +A ED GD ++ L+KKHE F+ ++++ + + LIK N++ +
Sbjct: 598 KMTLVASED-YGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENI 656
Query: 2847 TRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENY-RD 2671
+ K + + + L++A Q++ KL E+ QF+ AD +E+W+ EK + ++Y RD
Sbjct: 657 SSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRD 716
Query: 2670 PTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWD 2491
+++Q KQ+ F+A L A A I A + + AK + A+ AR +L +W
Sbjct: 717 LSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSK-AIEARHASLMKRWT 775
Query: 2490 LLVKTTTEKSYRLKEANKQ--------KSFMAAVKDLEFWLGEVEILLQSEDYGKDLASV 2335
L+ + + +L EA +F W E L L +
Sbjct: 776 QLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEI 835
Query: 2334 ENLLKKHSLLEADIVAHQ---DRVGEMNEQADSL--------------LENDQFQGQQIA 2206
+ L + H + + + Q +++ E++ Q S LE Q+I
Sbjct: 836 KALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFTMEALEETWRNLQKII 895
Query: 2205 ERRKLIADRYDGVKKMATDRRDKLSK--ALNVHQFFRDIDDEESWIKEKKLLVSSDDYGR 2032
+ R+L + ++ + DKL + A + + F + I + +++ + +V ++ G
Sbjct: 896 KERELELQK----EQRRQEENDKLRQEFAQHANAFHQWIQETRTYLLDGSCMV--EESGT 949
Query: 2031 DLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRME-DLEQ 1855
++ +RKH+ E+ + Q+ K E+L + EA + +++ + L Q
Sbjct: 950 LESQLEATKRKHQ----EIRAMRSQLK----KIEDLGAAMEEALILDNKYTEHSTVGLAQ 1001
Query: 1854 SWGQIRDLTGNRHQRLDESEAFQ 1786
W Q+ L L+ ++ Q
Sbjct: 1002 QWDQLDQLGMRMQHNLEHADPGQ 1024
Score = 263 bits (671), Expect = 6e-68
Identities = 214/907 (23%), Positives = 403/907 (43%), Gaps = 37/907 (4%)
Frame = -1
Query: 4152 AQQHAQQQVNSIGGKQSEIEDKY-QRLMMLGETRKRKLEEACKGYQLL-REANDLAEWIK 3979
A +++++ + +++++E + QR MML + C QL R+ W+
Sbjct: 121 ASPEIKEKLDILDQERTDLEKAWVQRRMML---------DHCLELQLFHRDCEQAENWMA 171
Query: 3978 SREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVR 3799
+REA ++ G L+ VE L KK +DF + E ++ + A L +V
Sbjct: 172 AREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAVDHYAKGDI 231
Query: 3798 IRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGR 3619
++ E L+ RWR L +LG + +Q+F RDVDE WI EK E + +
Sbjct: 232 ANRRNEVLD-RWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESY-K 289
Query: 3618 DLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRL--RQSHPEAAEQIYDLQRELNEQW 3445
D ++Q+ +KH+ E +L A D+I+ + + N L R + + + + L +QW
Sbjct: 290 DPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQW 349
Query: 3444 NRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERH 3265
L K+ + +KL ++ Q F + +D W++ + L++S++ D+ LL++H
Sbjct: 350 QFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKH 409
Query: 3264 QEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNIL 3085
Q +I + + + + L+ S + ++ + +N + ++ +RR L
Sbjct: 410 QALEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKL 469
Query: 3084 DQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGD--NVESLIKKHEDFDKAINTQEEKI 2911
+ L F+RD + ++W+ ++ ++ ED D V++L KKH+ + + E I
Sbjct: 470 SESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAI 529
Query: 2910 KGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDAD 2731
+G+ + L +N + ++ Q ++ W LK+ + +L ES QQF + +
Sbjct: 530 QGVLDTGKKLSDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVE 589
Query: 2730 EIENWMTEKFQIAQEENYRDP-TNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENA 2554
E E W+ EK + E+Y D IQ +K +AFE + + DR+ + G +LI+
Sbjct: 590 EEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIK-- 647
Query: 2553 KCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEIL 2374
K E +S+++K LN + L K ++ +L E + F +E W+GE E
Sbjct: 648 KNNHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENS 707
Query: 2373 LQSEDYGKDLASVENLLKKHSLLEADIVA-HQDRVGEMNEQADSLLENDQFQGQQIAERR 2197
L+++DYG+DL+SV+ LL K +A + A Q+ + + D LL Q + I R
Sbjct: 708 LKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARH 767
Query: 2196 KLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDD-----------EESWIKEKKLLVS 2050
+ R+ + + R+ KL L FR ++D SW + + ++
Sbjct: 768 ASLMKRWTQLLANSATRKKKL---LEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLT 824
Query: 2049 SDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIK-KR 1873
L ++ LR H + L+S + + + EL R V +
Sbjct: 825 DPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQL----AELDRQIKSFRVASNPYTWFT 880
Query: 1872 MEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEA--------WMNEKQQIL--G 1723
ME LE++W ++ + R L + + Q + +E A W+ E + L G
Sbjct: 881 MEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRTYLLDG 940
Query: 1722 S---DNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPH----I 1564
S + G + ++ +KH + + +++ DL + + N + H +
Sbjct: 941 SCMVEESGTLESQLEATKRKHQEIRA-MRSQLKKIEDLGAAMEEALILDNKYTEHSTVGL 999
Query: 1563 KQRCDQL 1543
Q+ DQL
Sbjct: 1000 AQQWDQL 1006
Score = 140 bits (354), Expect = 4e-31
Identities = 119/603 (19%), Positives = 252/603 (41%), Gaps = 9/603 (1%)
Frame = -1
Query: 2265 MNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDE 2086
+ E A L+++ + + E+ + + + K A R+ KL + ++ +F D D
Sbjct: 1 LGETAQRLIQSHPESAEDLKEKCTELNQAWTSLGKRAYQRKAKLGDSHDLQRFLSDFRDL 60
Query: 2085 ESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAE 1906
SWI + LVSSD+ +D+ G + L +H+ TE+ + + G++LL A
Sbjct: 61 MSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLL---AH 117
Query: 1905 AGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQIL 1726
+IK++++ L+Q + R LD Q F D E+ E WM ++ L
Sbjct: 118 GHYASPEIKEKLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWMAAREAFL 177
Query: 1725 GSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQ 1546
+++ G+++ V+ L+KKH+ F + + ++++A L D LI ++ I R ++
Sbjct: 178 NTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAVDHYAKGDIANRRNE 237
Query: 1545 LRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQI 1366
+ R +++ + +KL ++ QF D +E+WI+EK Q E + +D +++Q
Sbjct: 238 VLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESY-KDPTNIQS 296
Query: 1365 LLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEH--QQSPAIEKRHTNVIQRWQNLLAH 1192
K +AF+A L+A + I+ + ++ + L+ A++ R + +WQ L+
Sbjct: 297 KHQKHQAFEAELHA-NADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQFLVQK 355
Query: 1191 SEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRD 1012
S + F F+ W E L L + L
Sbjct: 356 SAEKSQKLKEANKQQN--------FNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLK 407
Query: 1011 AHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQ 832
H + +S+ E+ + L + + + D + ++ ++ + R
Sbjct: 408 KHQALEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRA 467
Query: 831 ELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEMMEAGGTLEEQLDAVERKAK---- 664
+L+ H+ + F + + +W+ ++++ + L V+ K
Sbjct: 468 KLSESHRLHQ--------FFRDMDDEESWIKE--KKLLVSSEDYGRDLTGVQNLRKKHKR 517
Query: 663 ---EIKANKGQLRQIEEKGAMLERNLILDNRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQ 493
E+ A++ ++ + + G L + + + + W +L QLA LE+
Sbjct: 518 LEAELAAHEPAIQGVLDTGKKLSDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEE 577
Query: 492 QIQ 484
++
Sbjct: 578 SLE 580
>gi|17862818|gb|AAL39886.1| LP06350p [Drosophila melanogaster]
Length = 856
Score = 1115 bits (2884), Expect = 0.0
Identities = 545/858 (63%), Positives = 677/858 (78%)
Frame = -1
Query: 2577 GNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEF 2398
G NLI+ +C G E AV RL + DQW+ L TTEKS +LKEANKQ++++AAVKDL+F
Sbjct: 2 GGNLIDKKQCSGSEDAVQKRLTQIADQWEYLTHKTTEKSLKLKEANKQRTYIAAVKDLDF 61
Query: 2397 WLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQG 2218
WLGEVE LL +ED GKDLASV+NL+KKH L+EADIVAH+DR+ +MN QADSL+E+ QF
Sbjct: 62 WLGEVESLLTTEDSGKDLASVQNLMKKHQLVEADIVAHEDRIKDMNNQADSLVESGQFDT 121
Query: 2217 QQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDY 2038
I E+R+ I +RY+ + +A R+ +L++AL +HQFFRDI DEESWIKEKKLLV SDDY
Sbjct: 122 AGIQEKRQSINERYERICNLAAHRQARLNEALTLHQFFRDIADEESWIKEKKLLVGSDDY 181
Query: 2037 GRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLE 1858
GRDL GVQNL++KH+R++ EL SHEP + V+ GE+L+ + +G +I++R++ L
Sbjct: 182 GRDLTGVQNLKKKHKRLEAELGSHEPAIQAVQEAGEKLMDVS---NLGVPEIEQRLKALN 238
Query: 1857 QSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLL 1678
Q+W ++++L R Q+LDES +Q FL VEEEEAW+ EKQQ+L +++G++MA VQGLL
Sbjct: 239 QAWAELKNLAATRGQKLDESLTYQQFLAQVEEEEAWITEKQQLLSVEDYGDSMAAVQGLL 298
Query: 1677 KKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRL 1498
KKHD F+ D HK R + + ++G L+ NHH I QRC QLR +L + ++A R
Sbjct: 299 KKHDAFETDFTAHKDRCSLICDQGSELVEAKNHHGESIAQRCQQLRLKLDNLSALAARRK 358
Query: 1497 AKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFE 1318
L DNSAYLQFMWK DVVESWI +KE VRS++FGRDLS+VQ LLTKQE FDAGLNAFE
Sbjct: 359 GALLDNSAYLQFMWKADVVESWIDDKENYVRSDEFGRDLSTVQTLLTKQETFDAGLNAFE 418
Query: 1317 HEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQI 1138
EGI IT LKDQL+++ H QSPAI KRH +VI RWQ L S R+ QI
Sbjct: 419 QEGIHNITALKDQLINASHAQSPAILKRHGDVIARWQKLRDASNTRKDRLLAMQEQFRQI 478
Query: 1137 EELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQ 958
EELYL FAKKAS FNSWFENAEEDLTDPVRCNS+EEIRALRDAH +FQ SLSSAE DF+
Sbjct: 479 EELYLTFAKKASAFNSWFENAEEDLTDPVRCNSIEEIRALRDAHAQFQASLSSAEADFKA 538
Query: 957 LQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRRE 778
L LD++IKSFNVGPNPYTWFTM+ALE+TWRNLQ+II+ER+ ELA+E +RQEENDKLR+E
Sbjct: 539 LAALDQKIKSFNVGPNPYTWFTMEALEETWRNLQKIIEERDGELAKEAKRQEENDKLRKE 598
Query: 777 FAKLANAFHAWLTNTRQEMMEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERN 598
FAK AN FH WLT TR MME G+LE+QL+A+ KA E++A + L++IEE GA+LE +
Sbjct: 599 FAKHANLFHQWLTETRTSMMEGSGSLEQQLEALRVKATEVRARRVDLKKIEELGALLEEH 658
Query: 597 LILDNRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMMFKHF 418
LILDNRYTEHSTVG+AQ WDQLDQL+MRMQHNLEQQIQARN SGVSE++L+EFSMMFKHF
Sbjct: 659 LILDNRYTEHSTVGLAQQWDQLDQLSMRMQHNLEQQIQARNHSGVSEDSLKEFSMMFKHF 718
Query: 417 DKEKTGRLDHQQFKSCLRALGYDLPMVDEGQPEPEFQRILDIVDPNRDGYVTLQEYMAFM 238
DK+K+G+L+HQ+FKSCLRALGYDLPMV+EGQP+PEF+ ILD+VDPNRDGYV+LQEY+AFM
Sbjct: 719 DKDKSGKLNHQEFKSCLRALGYDLPMVEEGQPDPEFEAILDVVDPNRDGYVSLQEYIAFM 778
Query: 237 ISKETENIQSSEEIEMAFRALSKEFRPYVTAEELYANLTPEQAEFCIRRMKPYMDAISGR 58
ISKETEN+QS EEIE AFRA++ RPYVT EELY NLT + A++C++RMKP+ + SG+
Sbjct: 779 ISKETENVQSYEEIENAFRAITAADRPYVTKEELYCNLTKDMADYCVQRMKPFSEPRSGQ 838
Query: 57 SIQGGLDYEQFVHALFQS 4
I+ LDY F LFQ+
Sbjct: 839 PIKDALDYIDFTRTLFQN 856
Score = 214 bits (545), Expect = 3e-53
Identities = 113/309 (36%), Positives = 174/309 (55%)
Frame = -1
Query: 5295 DHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDY 5116
D + RL Q+ + W L T +K KL+EA ++ + ++D++ WL E+E + +ED
Sbjct: 16 DAVQKRLTQIADQWEYLTHKTTEKSLKLKEANKQRTYIAAVKDLDFWLGEVESLLTTEDS 75
Query: 5115 GKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRY 4936
GKDL SVQNL KK L+E+D AH DR+ + A E F+ I K++++ +RY
Sbjct: 76 GKDLASVQNLMKKHQLVEADIVAHEDRIKDMNNQADSLVESGQFDTAGIQEKRQSINERY 135
Query: 4935 NALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQ 4756
+ + R+ +L E+ +Q FRDI DE +WI+EK+ + GS + GRDL GVQNL KK
Sbjct: 136 ERICNLAAHRQARLNEALTLHQFFRDIADEESWIKEKKLLVGSDDYGRDLTGVQNLKKKH 195
Query: 4755 QALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDL 4576
+ L AE+ +H+ I++V A ++ + PEI +L L W LK+ A R L
Sbjct: 196 KRLEAELGSHEPAIQAVQEAGEKLMDVSNLGVPEIEQRLKALNQAWAELKNLAATRGQKL 255
Query: 4575 DDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTI 4396
D+SL Q+L+ E +AW++EK+ ++ DYG + + LLKKH A +D A K
Sbjct: 256 DESLTYQQFLAQVEEEEAWITEKQQLLSVEDYGDSMAAVQGLLKKHDAFETDFTAHKDRC 315
Query: 4395 EDLRKQASQ 4369
+ Q S+
Sbjct: 316 SLICDQGSE 324
Score = 192 bits (488), Expect = 1e-46
Identities = 161/694 (23%), Positives = 298/694 (42%), Gaps = 41/694 (5%)
Frame = -1
Query: 6888 ASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAE 6709
+ + ++KRL ++ W K +KL++A K +I ++ +W+ E E+ +T E
Sbjct: 14 SEDAVQKRLTQIADQWEYLTHKTTEKSLKLKEANKQRTYIAAVKDLDFWLGEVESLLTTE 73
Query: 6708 DMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVND 6529
D G DL V+ L +K ++ H+ RI ++N AD LVE G + I +KR +N+
Sbjct: 74 DSGKDLASVQNLMKKHQLVEADIVAHEDRIKDMNNQADSLVESGQFDTAGIQEKRQSINE 133
Query: 6528 AWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQR 6349
+ R+ LAA R+ L A + +F RD + +WI EK L + SDDYGRDL VQ L++
Sbjct: 134 RYERICNLAAHRQARLNEALTLHQFFRDIADEESWIKEKKLLVGSDDYGRDLTGVQNLKK 193
Query: 6348 KHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKD 6169
KH+ E +L + E + +++ KL + I Q+ AW LK A R
Sbjct: 194 KHKRLEAELGSHEPAIQAVQEAGEKLMDVSNLGVPEIEQRLKALNQAWAELKNLAATRGQ 253
Query: 6168 GLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARAD 5989
L+ S +FLA + +WI + + ++ ++ +A + LL+ H + + A D
Sbjct: 254 KLDESLTYQQFLAQVEEEEAWITEKQQLLSVEDYGDSMAAVQGLLKKHDAFETDFTAHKD 313
Query: 5988 SFNQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERR-ILYEQCMDLQLFYR 5812
+ G +LVE + ++ ++L + +L L R+ L + LQ ++
Sbjct: 314 RCSLICDQGSELVEAKNHHGESIAQRCQQLRLKLDNLSALAARRKGALLDNSAYLQFMWK 373
Query: 5811 DTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSL-AAQEEKINALDEFATKL 5635
+ E+W++ +E ++ + + G L +V+ L+ K E F+ L A ++E I+ + +L
Sbjct: 374 -ADVVESWIDDKENYVRSDEFGRDLSTVQTLLTKQETFDAGLNAFEQEGIHNITALKDQL 432
Query: 5634 IQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGN---ALKESYKR-----QTFDRDCDEM 5479
I H + + + R + A++E +++ TF +
Sbjct: 433 INASHAQSPAILKRHGDVIARWQKLRDASNTRKDRLLAMQEQFRQIEELYLTFAKKASAF 492
Query: 5478 VSWITEKLSTARDDSYLDPT------NIRGKLQKHINFEQELKANENRLDDIRSTGEQII 5317
SW ++ DP IR H F+ L + E + + ++I
Sbjct: 493 NSWFEN-----AEEDLTDPVRCNSIEEIRALRDAHAQFQASLSSAEADFKALAALDQKIK 547
Query: 5316 DSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEA------- 5158
+ + + W L ++ +L + Q+ N + A
Sbjct: 548 SFNVGPNPYTWFTMEALEETWRNLQKIIEERDGELAKEAKRQEENDKLRKEFAKHANLFH 607
Query: 5157 -WLSE-----LEGQVASEDYGKDL-----------VSVQNLQKKIGLIESDFNAHNDRVD 5029
WL+E +EG + E + L V ++ +++ L+E N +
Sbjct: 608 QWLTETRTSMMEGSGSLEQQLEALRVKATEVRARRVDLKKIEELGALLEEHLILDNRYTE 667
Query: 5028 -GIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNA 4930
LAQQ+ + + + +R Q NL+Q+ A
Sbjct: 668 HSTVGLAQQWDQLDQLS----MRMQHNLEQQIQA 697
Score = 181 bits (459), Expect = 2e-43
Identities = 105/399 (26%), Positives = 202/399 (50%), Gaps = 5/399 (1%)
Frame = -1
Query: 5529 LKESYKRQTFDRDCDEMVSWITEKLST-ARDDSYLDPTNIRGKLQKHINFEQELKANENR 5353
LKE+ K++T+ ++ W+ E S +DS D +++ ++KH E ++ A+E+R
Sbjct: 43 LKEANKQRTYIAAVKDLDFWLGEVESLLTTEDSGKDLASVQNLMKKHQLVEADIVAHEDR 102
Query: 5352 LDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNI 5173
+ D+ + + +++SG F I ++ + +N + + + + A+L EA QF R+I
Sbjct: 103 IKDMNNQADSLVESGQFDTAGIQEKRQSINERYERICNLAAHRQARLNEALTLHQFFRDI 162
Query: 5172 EDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEE 4993
D E+W+ E + V S+DYG+DL VQNL+KK +E++ +H + +++ ++ +
Sbjct: 163 ADEESWIKEKKLLVGSDDYGRDLTGVQNLKKKHKRLEAELGSHEPAIQAVQEAGEKLMDV 222
Query: 4992 EHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVA 4813
+ P I ++ + L Q + L++ R +KL ES Q +E+E AWI EK+Q+
Sbjct: 223 SNLGVPEIEQRLKALNQAWAELKNLAATRGQKLDESLTYQQFLAQVEEEEAWITEKQQLL 282
Query: 4812 GSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQ 4633
+ G + VQ L+KK A + H + + +++++ + I + Q
Sbjct: 283 SVEDYGDSMAAVQGLLKKHDAFETDFTAHKDRCSLICDQGSELVEAKNHHGESIAQRCQQ 342
Query: 4632 LRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEA 4453
LR L + A +R+ L D+ Q++ A+ ++W+ +KE V S ++G+D + +
Sbjct: 343 LRLKLDNLSALAARRKGALLDNSAYLQFMWKADVVESWIDDKENYVRSDEFGRDLSTVQT 402
Query: 4452 LLKKHRALLSDLEAFK----GTIEDLRKQASQCKYQEQP 4348
LL K + L AF+ I L+ Q + + P
Sbjct: 403 LLTKQETFDAGLNAFEQEGIHNITALKDQLINASHAQSP 441
Score = 176 bits (447), Expect = 6e-42
Identities = 126/535 (23%), Positives = 247/535 (45%), Gaps = 14/535 (2%)
Frame = -1
Query: 7197 DDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWI--LEKLQTAQEE 7024
D + +R ++ + + K +L+EA + + + +L+ W+ +E L T E+
Sbjct: 16 DAVQKRLTQIADQWEYLTHKTTEKSLKLKEANKQRTYIAAVKDLDFWLGEVESLLTT-ED 74
Query: 7023 NFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHAL 6844
+ +D +++Q ++KH+ EA++ AH I +++ +++++ F + I+++ + ++
Sbjct: 75 SGKDLASVQNLMKKHQLVEADIVAHEDRIKDMNNQADSLVESGQFDTAGIQEKRQSINER 134
Query: 6843 WXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRK 6664
+ + +L +AL L F R + WI+EK+ V ++D G DL V+ L++K
Sbjct: 135 YERICNLAAHRQARLNEALTLHQFFRDIADEESWIKEKKLLVGSDDYGRDLTGVQNLKKK 194
Query: 6663 FDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEG 6484
ELG+H+ I + +A +KL++ + +I ++ +N AW L LAATR +
Sbjct: 195 HKRLEAELGSHEPAIQAVQEAGEKLMDVSNLGVPEIEQRLKALNQAWAELKNLAATRGQK 254
Query: 6483 LFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGK 6304
L + Q+F +E AWI EK LS +DYG + VQ L +KH+ E D A + +
Sbjct: 255 LDESLTYQQFLAQVEEEEAWITEKQQLLSVEDYGDSMAAVQGLLKKHDAFETDFTAHKDR 314
Query: 6303 MLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADY 6124
+ + +L E E+I Q+ + + L A RK L + +F+
Sbjct: 315 CSLICDQGSELVEAKNHHGESIAQRCQQLRLKLDNLSALAARRKGALLDNSAYLQFMWKA 374
Query: 6123 RDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDA-RADSFNQTASAGQKLVE 5947
+ SWI D + + +DE +D++ + LL + ++A + + + +L+
Sbjct: 375 DVVESWIDDKENYVRSDEFGRDLSTVQTLLTKQETFDAGLNAFEQEGIHNITALKDQLIN 434
Query: 5946 MGIPESPEV-----------QEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQ 5800
+SP + Q+ + + K LL + E+ R + E + F +
Sbjct: 435 ASHAQSPAILKRHGDVIARWQKLRDASNTRKDRLLAMQEQFRQIEELYL---TFAKKASA 491
Query: 5799 AETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKL 5635
+W E L + +S++ + L H F+ SL++ E AL K+
Sbjct: 492 FNSWFENAEEDLTDPVRCNSIEEIRALRDAHAQFQASLSSAEADFKALAALDQKI 546
Score = 172 bits (437), Expect = 8e-41
Identities = 115/462 (24%), Positives = 224/462 (47%), Gaps = 7/462 (1%)
Frame = -1
Query: 3798 IRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGR 3619
+++++ + +W L +L A++ + + V + W+ E + L +ED G+
Sbjct: 18 VQKRLTQIADQWEYLTHKTTEKSLKLKEANKQRTYIAAVKDLDFWLGEVESLLTTEDSGK 77
Query: 3618 DLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNR 3439
DL SVQ L +KH+ VE D+ A D+IK ++ +A+ L +S I + ++ +NE++ R
Sbjct: 78 DLASVQNLMKKHQLVEADIVAHEDRIKDMNNQADSLVESGQFDTAGIQEKRQSINERYER 137
Query: 3438 LTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQE 3259
+ + A +R+ +L ++ +F D D WI LV S + D+TG + L ++H+
Sbjct: 138 ICNLAAHRQARLNEALTLHQFFRDIADEESWIKEKKLLVGSDDYGRDLTGVQNLKKKHKR 197
Query: 3258 YRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQ 3079
E+ S QA + G +L++ + +IE RL+ +N+A L++ R LD+
Sbjct: 198 LEAELGSHEPAIQAVQEAGEKLMDVSNLGVPEIEQRLKALNQAWAELKNLAATRGQKLDE 257
Query: 3078 CLELQLFYRDCEQADTWMSAREAFLAQEDPSGDN---VESLIKKHEDFDKAINTQEEKIK 2908
L Q F E+ + W++ ++ L+ ED GD+ V+ L+KKH+ F+ +++
Sbjct: 258 SLTYQQFLAQVEEEEAWITEKQQLLSVED-YGDSMAAVQGLLKKHDAFETDFTAHKDRCS 316
Query: 2907 GLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADE 2728
+ L++ ++ ++ ++ Q+ + + L +++ L ++ QF AD
Sbjct: 317 LICDQGSELVEAKNHHGESIAQRCQQLRLKLDNLSALAARRKGALLDNSAYLQFMWKADV 376
Query: 2727 IENWMTEKFQIAQEENY-RDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAK 2551
+E+W+ +K + + + RD + +Q KQ+ F+A L+A I A + + NA
Sbjct: 377 VESWIDDKENYVRSDEFGRDLSTVQTLLTKQETFDAGLNAFEQEGIHNITALKDQLINA- 435
Query: 2550 CGGGEAAVSARLKALND---QWDLLVKTTTEKSYRLKEANKQ 2434
A A LK D +W L + + RL +Q
Sbjct: 436 ---SHAQSPAILKRHGDVIARWQKLRDASNTRKDRLLAMQEQ 474
Score = 157 bits (398), Expect = 3e-36
Identities = 138/608 (22%), Positives = 255/608 (41%), Gaps = 28/608 (4%)
Frame = -1
Query: 4146 QHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREA 3967
+ Q I K+ I ++Y+R+ L R+ +L EA +Q R+ D WIK ++
Sbjct: 115 ESGQFDTAGIQEKRQSINERYERICNLAAHRQARLNEALTLHQFFRDIADEESWIKEKKL 174
Query: 3966 VAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQ 3787
+ + G DL V+ L+KK + +L ++E +Q + + L V I Q+
Sbjct: 175 LVGSDDYGRDLTGVQNLKKKHKRLEAELGSHEPAIQAVQEAGEKLMDVSNLGVP-EIEQR 233
Query: 3786 IEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRS 3607
++ LN W L +L + Q+F V+E WI EK L ED+G + +
Sbjct: 234 LKALNQAWAELKNLAATRGQKLDESLTYQQFLAQVEEEEAWITEKQQLLSVEDYGDSMAA 293
Query: 3606 VQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSK 3427
VQ L +KH+ E D A D+ + ++ + L ++ E I ++L + + L++
Sbjct: 294 VQGLLKKHDAFETDFTAHKDRCSLICDQGSELVEAKNHHGESIAQRCQQLRLKLDNLSAL 353
Query: 3426 ANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTE 3247
A RK LLD+ Y +F+ + WI V S E D++ + LL + + +
Sbjct: 354 AARRKGALLDNSAYLQFMWKADVVESWIDDKENYVRSDEFGRDLSTVQTLLTKQETF--- 410
Query: 3246 IDSRAATFQAFDQFG--------NQLLNSHHYAA-------GDIENRLQGVNEARKGLED 3112
A AF+Q G +QL+N+ H + GD+ R Q + +A +D
Sbjct: 411 ----DAGLNAFEQEGIHNITALKDQLINASHAQSPAILKRHGDVIARWQKLRDASNTRKD 466
Query: 3111 AWVARRNILDQCLELQL-FYRDCEQADTWMSAREAFLAQEDP----SGDNVESLIKKHED 2947
+A + Q EL L F + ++W E L DP S + + +L H
Sbjct: 467 RLLAMQEQFRQIEELYLTFAKKASAFNSWFENAEEDLT--DPVRCNSIEEIRALRDAHAQ 524
Query: 2946 FDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGE 2767
F ++++ E K L + + N +P + + + W L++ + ++ +L +
Sbjct: 525 FQASLSSAEADFKALAALDQKIKSFNVGPNPYTWFTMEALEETWRNLQKIIEERDGELAK 584
Query: 2766 SQTLQ--------QFSRDADEIENWMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHA 2611
Q +F++ A+ W+TE E + +++Q+ + + E+ A
Sbjct: 585 EAKRQEENDKLRKEFAKHANLFHQWLTETRTSMMEGS----GSLEQQLEALRVKATEVRA 640
Query: 2610 NSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQK 2431
+ I + G L E+ S L QWD L + + + L++ + +
Sbjct: 641 RRVDLKKIEELGALLEEHLILDNRYTEHST--VGLAQQWDQLDQLSMRMQHNLEQQIQAR 698
Query: 2430 SFMAAVKD 2407
+ +D
Sbjct: 699 NHSGVSED 706
>gi|178426|gb|AAA51702.1| alpha-fodrin
gi|537331|gb|AAA52468.1| alpha-fodrin
Length = 920
Score = 1031 bits (2665), Expect = 0.0
Identities = 523/919 (56%), Positives = 661/919 (71%), Gaps = 60/919 (6%)
Frame = -1
Query: 5208 EAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVD 5029
EA +QQFNRN+ED+E WL E+EG +AS+DYGKDL +VQNLQKK L+E+D AH DR+D
Sbjct: 1 EANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTNVQNLQKKHALLEADVAAHQDRID 60
Query: 5028 GIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIED 4849
G+ A+QFQ+ HF+A I +KQE L RY AL++P+ RK+KL +S + QLFRD+ED
Sbjct: 61 GVTIQARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKLADSLRLQQLFRDVED 120
Query: 4848 ELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGH 4669
E WIREKE +A STNRG+DLIGVQNL+KK QAL AEIA H+ +I++V+ N M+++GH
Sbjct: 121 EETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGH 180
Query: 4668 FLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGS 4489
F A +++ KL +L W LK+KA +RR DL+DSLQA QY +DANEA++WM EKEPIVGS
Sbjct: 181 FAAEDVKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGS 240
Query: 4488 TDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQPMG-QLGRDCVLAL 4312
TDYGKDEDSAEALLKKH AL+SDL A+ +I+ LR+QA C+ Q P + G++ VLAL
Sbjct: 241 TDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPTDDETGKELVLAL 300
Query: 4311 YDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIEPGTA------ 4150
YDYQEKSPREV+MKKGD+LTLLN++N+DWWKVEVNDRQGFVPAAYVK+++P +
Sbjct: 301 YDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVKKLDPAQSASRENL 360
Query: 4149 ----------------QQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQ 4018
Q ++ S+ + ++E+ Y L+ LGE RK LE++CK +
Sbjct: 361 LEEQGSIALRQEQIDNQTRITKEAGSVSLRMKQVEELYHSLLELGEKRKGMLEKSCKKFM 420
Query: 4017 LLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIAT 3838
L REAN+L +WI +EA +E+G DLEQVEVLQKKFDDF+ DLKANE RL+++N++A
Sbjct: 421 LFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAE 480
Query: 3837 ALTSVGQTETAVRIRQQ-----------------------------------IEDLNARW 3763
L S G V+ QQ I++LN RW
Sbjct: 481 DLESEGLMAEEVQAVQQQEVYGMMPRDETDSKTASPWKSARLMVHTVATFNSIKELNERW 540
Query: 3762 RALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKH 3583
R+L LGSAHEVQRFHRD DET++WI+EK+ AL+++++G DL SVQALQRKH
Sbjct: 541 RSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKH 600
Query: 3582 EGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKL 3403
EG ERDLAALGDK+ SL E A RL QSHPE+AE + + ELN+ W+ L +A+ RK KL
Sbjct: 601 EGFERDLAALGDKVNSLGETAERLTQSHPESAEDLQEKCTELNQAWSSLGKRADQRKAKL 660
Query: 3402 LDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATF 3223
DS+D QRFLSD+RDLM WI + LVSS ELA DVTGAEALLERHQE+RTEID+RA TF
Sbjct: 661 GDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTF 720
Query: 3222 QAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCE 3043
QAF+QFG QLL HYA+ +I+ +L +++ R LE AWV RR +LDQCLELQLF+RDCE
Sbjct: 721 QAFEQFGQQLLAHGHYASPEIKQKLDILDQERADLEKAWVQRRMMLDQCLELQLFHRDCE 780
Query: 3042 QADTWMSAREAFLAQED--PSGDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNN 2869
QA+ WM+AREAFL ED S D+VE+LIKKHEDFDKAIN QEEKI L+ FA+ LI
Sbjct: 781 QAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAAG 840
Query: 2868 HYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQ 2689
HY ++ +R+++LDRW LK +I+KR KLGESQTLQQFSRD DEIE W++EK Q A
Sbjct: 841 HYAKGDISSRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTAS 900
Query: 2688 EENYRDPTNIQQKHQKQQA 2632
+E+Y+DPTNIQ KHQK QA
Sbjct: 901 DESYKDPTNIQSKHQKHQA 919
Score = 429 bits (1103), Expect = e-118
Identities = 232/531 (43%), Positives = 326/531 (60%), Gaps = 36/531 (6%)
Frame = -1
Query: 6876 IKKRLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGM 6697
+ R++++ L+ + L+++ K R+ +E+ WI EKE +T+E++G
Sbjct: 387 VSLRMKQVEELYHSLLELGEKRKGMLEKSCKKFMLFREANELQQWINEKEAALTSEEVGA 446
Query: 6696 DLEHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEG-HSEHDQIYKKRD------- 6541
DLE VE+LQ+KFDDF K+L ++ R+ +IN+ A+ L EG +E Q ++++
Sbjct: 447 DLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYGMMPR 506
Query: 6540 ----------------------------DVNDAWHRLNTLAATRKEGLFGAHQVQRFNRD 6445
++N+ W L LA R + L AH+VQRF+RD
Sbjct: 507 DETDSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRD 566
Query: 6444 ADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAE 6265
ADET WI EK+ AL++D+YG DL +VQALQRKHEG ERDLAAL K+ L + A +L +
Sbjct: 567 ADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAERLTQ 626
Query: 6264 THPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAV 6085
+HP+ AE + +K + AW++L ++A RK L S L RFL+D+RDL+SWI ++ +
Sbjct: 627 SHPESAEDLQEKCTELNQAWSSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGL 686
Query: 6084 IGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLE 5905
+ +DELAKDV GAEALLE HQEH+ EIDARA +F GQ+L+ G SPE+++KL+
Sbjct: 687 VSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKQKLD 746
Query: 5904 KLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVE 5725
LD E++ L W +RR++ +QC++LQLF+RD EQAE WM +EAFL D GDSLDSVE
Sbjct: 747 ILDQERADLEKAWVQRRMMLDQCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVE 806
Query: 5724 HLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXX 5545
LIKKHEDF+K++ QEEKI AL FA +LI HYA D++
Sbjct: 807 ALIKKHEDFDKAINVQEEKIAALQAFADQLIAAGHYAKGDISSRRNEVLDRWRRLKAQMI 866
Query: 5544 XRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGKLQKH 5392
+ + L ES Q F RD DE+ +WI+EKL TA D+SY DPTNI+ K QKH
Sbjct: 867 EKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPTNIQSKHQKH 917
Score = 326 bits (836), Expect = 5e-87
Identities = 235/936 (25%), Positives = 436/936 (46%), Gaps = 43/936 (4%)
Frame = -1
Query: 7110 EARQFQYFKRDADELNVWILE-KLQTAQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIA 6934
EA Q Q F R+ +++ +W+ E + A ++ +D +N+Q +KH EA+V AH I
Sbjct: 1 EANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTNVQNLQKKHALLEADVAAHQDRID 60
Query: 6933 NLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDE 6754
+ HF +E+IKK+ E L A + + KL +L+L R ++
Sbjct: 61 GVTIQARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKLADSLRLQQLFRDVED 120
Query: 6753 ILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEGH 6574
WIREKE + + G DL V+ L +K E+ H+ RI + Q + +VEEGH
Sbjct: 121 EETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGH 180
Query: 6573 SEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSS 6394
+ + K ++N W L A+ R++ L + Q Q++ DA+E +W+ EK+ + S
Sbjct: 181 FAAEDVKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGS 240
Query: 6393 DDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTK 6214
DYG+D ++ +AL +KHE DL+A + L ++A + A + +
Sbjct: 241 TDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQ---QVAPTDDETGKELV 297
Query: 6213 AAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISW---IGDMKAVIGADELAKDVAGAE 6043
A +EK+ R+ +++ L + +D W + D + + A + K
Sbjct: 298 LALYDYQEKSP-REVTMKKGDILTLLNSTNKDW--WKVEVNDRQGFVPAAYVKKLDPAQS 354
Query: 6042 ALLESHQEHKGEIDARADSF-NQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLW 5866
A E+ E +G I R + NQT E+ V ++++++ SLL L
Sbjct: 355 ASRENLLEEQGSIALRQEQIDNQTRIT---------KEAGSVSLRMKQVEELYHSLLELG 405
Query: 5865 EERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSL 5686
E+R+ + E+ + +R+ + + W+N++EA L + ++G L+ VE L KK +DF+K L
Sbjct: 406 EKRKGMLEKSCKKFMLFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDL 465
Query: 5685 AAQEEKINALDEFATKLIQGQHYAADDV----------------AEXXXXXXXXXXXXXX 5554
A E ++ +++ A L + + A++V +
Sbjct: 466 KANESRLKDINKVAEDL-ESEGLMAEEVQAVQQQEVYGMMPRDETDSKTASPWKSARLMV 524
Query: 5553 XXXXRGNALKESYKR---------------------QTFDRDCDEMVSWITEKLSTARDD 5437
N++KE +R Q F RD DE WI EK D
Sbjct: 525 HTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTD 584
Query: 5436 SY-LDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNN 5260
+Y D +++ +KH FE++L A ++++ + T E++ S +A+ + ++ ++N
Sbjct: 585 NYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAERLTQSHPESAEDLQEKCTELNQ 644
Query: 5259 LWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQK 5080
W+ L +++ AKL ++ + Q+F + D+ +W++ + G V+S++ KD+ + L +
Sbjct: 645 AWSSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLE 704
Query: 5079 KIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKR 4900
+ ++ +A +Q QQ H+ +P I +K + L Q L +R+
Sbjct: 705 RHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKQKLDILDQERADLEKAWVQRRM 764
Query: 4899 KLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDS 4720
L + + RD E W+ +E + ++G L V+ LIKK + I +
Sbjct: 765 MLDQCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEE 824
Query: 4719 QIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSD 4540
+I ++ + A+ +I GH+ +I + ++ D WR LK++ ++R+ L +S Q+ D
Sbjct: 825 KIAALQAFADQLIAAGHYAKGDISSRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRD 884
Query: 4539 ANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRA 4432
+E +AW+SEK Y KD + ++ +KH+A
Sbjct: 885 VDEIEAWISEKLQTASDESY-KDPTNIQSKHQKHQA 919
Score = 299 bits (766), Expect = 6e-79
Identities = 231/938 (24%), Positives = 432/938 (45%), Gaps = 40/938 (4%)
Frame = -1
Query: 4038 EACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQ 3859
EA + Q R D+ W+ E A + G DL V+ LQKK + D+ A++ R+
Sbjct: 1 EANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTNVQNLQKKHALLEADVAAHQDRID 60
Query: 3858 EMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVD 3679
+ A G + A I+++ E L AR+ AL +L + +Q+ RDV+
Sbjct: 61 GVTIQARQFQDAGHFD-AENIKKKQEALVARYEALKEPMVARKQKLADSLRLQQLFRDVE 119
Query: 3678 ETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSH 3499
+ WI+EK+ S + G+DL VQ L +KH+ ++ ++A +IK++ +K N + +
Sbjct: 120 DEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEG 179
Query: 3498 PEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVS 3319
AAE + ELN++W L +KA+ R++ L DS Q++ +D + W+ +V
Sbjct: 180 HFAAEDVKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVG 239
Query: 3318 SQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGV 3139
S + D AEALL++H+ +++ + ++ QA + A D E + V
Sbjct: 240 STDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSC--RQQVAPTDDETGKELV 297
Query: 3138 ----NEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGD-NV 2974
+ K + + + +IL + E D A++ + DP+ +
Sbjct: 298 LALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVKKLDPAQSASR 357
Query: 2973 ESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEAL 2794
E+L+++ +I ++E+I + ++ +V+ + Q+ + ++ L E
Sbjct: 358 ENLLEEQG----SIALRQEQIDNQTRITK--------EAGSVSLRMKQVEELYHSLLELG 405
Query: 2793 IQKRFKLGESQTLQQFSRDADEIENWMTEK-FQIAQEENYRDPTNIQQKHQKQQAFEAEL 2617
+++ L +S R+A+E++ W+ EK + EE D ++ +K F+ +L
Sbjct: 406 EKRKGMLEKSCKKFMLFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDL 465
Query: 2616 HANSDRIAAIIQAGNNLIENAKCGGGEAAV-----------------------SARL--- 2515
AN R+ I + +L AV SARL
Sbjct: 466 KANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYGMMPRDETDSKTASPWKSARLMVH 525
Query: 2514 --------KALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSED 2359
K LN++W L + E+S L A++ + F + + W+ E L +++
Sbjct: 526 TVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDN 585
Query: 2358 YGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADR 2179
YG DLASV+ L +KH E D+ A D+V + E A+ L ++ + + E+ +
Sbjct: 586 YGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAERLTQSHPESAEDLQEKCTELNQA 645
Query: 2178 YDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRK 1999
+ + K A R+ KL + ++ +F D D SWI + LVSSD+ +D+ G + L +
Sbjct: 646 WSSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLER 705
Query: 1998 HRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNR 1819
H+ TE+ + + G++LL A +IK++++ L+Q + R
Sbjct: 706 HQEHRTEIDARAGTFQAFEQFGQQLL---AHGHYASPEIKQKLDILDQERADLEKAWVQR 762
Query: 1818 HQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELH 1639
LD+ Q F D E+ E WM ++ L +++ G+++ V+ L+KKH+ F + +
Sbjct: 763 RMMLDQCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQ 822
Query: 1638 KQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFM 1459
++++A L D LI G++ I R +++ R +++ + +KL ++ QF
Sbjct: 823 EEKIAALQAFADQLIAAGHYAKGDISSRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFS 882
Query: 1458 WKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEA 1345
D +E+WI+EK Q E + +D +++Q K +A
Sbjct: 883 RDVDEIEAWISEKLQTASDESY-KDPTNIQSKHQKHQA 919
Score = 254 bits (648), Expect = 3e-65
Identities = 199/859 (23%), Positives = 376/859 (43%), Gaps = 42/859 (4%)
Frame = -1
Query: 7200 ADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEEN 7021
A++I ++++ ++ Y K+ ++ +L ++ + Q RD ++ WI EK A N
Sbjct: 77 AENIKKKQEALVARYEALKEPMVARKQKLADSLRLQQLFRDVEDEETWIREKEPIAASTN 136
Query: 7020 F-RDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHAL 6844
+D +Q ++KH+A +AE+ H I + + GNAM++ HFA+E +K +L EL+
Sbjct: 137 RGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLHELNQK 196
Query: 6843 WXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRK 6664
W + L+ +L+ + +E W+REKE V + D G D + E L +K
Sbjct: 197 WEALKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKK 256
Query: 6663 FDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEG 6484
+ + +L + I + + A ++ D+ K+ + + T K+G
Sbjct: 257 HEALMSDLSAYGSSIQALREQAQSCRQQVAPTDDETGKELVLALYDYQEKSPREVTMKKG 316
Query: 6483 ----LFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAA 6316
L + + + ++ ++ Y + L+ Q+ R++ E+ A
Sbjct: 317 DILTLLNSTNKDWWKVEVNDRQGFVPAA--------YVKKLDPAQSASRENLLEEQGSIA 368
Query: 6315 LEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRF 6136
L + + + K A ++ + + +++L E + RK LE+S +
Sbjct: 369 LRQEQIDNQTRITK-------EAGSVSLRMKQVEELYHSLLELGEKRKGMLEKSCKKFML 421
Query: 6135 LADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEI---DARADSFNQTA-- 5971
+ +L WI + +A + ++E+ D+ E L + + + ++ ++R N+ A
Sbjct: 422 FREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAED 481
Query: 5970 --SAGQKLVEMGIPESPEVQ-----------------------------EKLEKLDHEKS 5884
S G E+ + EV +++L+
Sbjct: 482 LESEGLMAEEVQAVQQQEVYGMMPRDETDSKTASPWKSARLMVHTVATFNSIKELNERWR 541
Query: 5883 SLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHE 5704
SL L EER L ++Q F+RD ++ + W+ ++ L + G L SV+ L +KHE
Sbjct: 542 SLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHE 601
Query: 5703 DFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALK 5524
FE+ LAA +K+N+L E A +L Q +A+D+ E R L
Sbjct: 602 GFERDLAALGDKVNSLGETAERLTQSHPESAEDLQEKCTELNQAWSSLGKRADQRKAKLG 661
Query: 5523 ESYKRQTFDRDCDEMVSWITE-KLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLD 5347
+S+ Q F D +++SWI + + D+ D T L++H E+ A
Sbjct: 662 DSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQ 721
Query: 5346 DIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIED 5167
G+Q++ GH+A+ I +L ++ +L A ++ L + Q F+R+ E
Sbjct: 722 AFEQFGQQLLAHGHYASPEIKQKLDILDQERADLEKAWVQRRMMLDQCLELQLFHRDCEQ 781
Query: 5166 VEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEH 4987
E W++ E + +ED G L SV+ L KK + N +++ ++ A Q H
Sbjct: 782 AENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAAGH 841
Query: 4986 FNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGS 4807
+ I ++ + R+ L+ + +++ KLGES Q RD+++ AWI EK Q A S
Sbjct: 842 YAKGDISSRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTA-S 900
Query: 4806 TNRGRDLIGVQNLIKKQQA 4750
+D +Q+ +K QA
Sbjct: 901 DESYKDPTNIQSKHQKHQA 919
Score = 236 bits (602), Expect = 6e-60
Identities = 176/691 (25%), Positives = 318/691 (45%), Gaps = 48/691 (6%)
Frame = -1
Query: 2448 EANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVG 2269
EAN+Q+ F V+D+E WL EVE L S+DYGKDL +V+NL KKH+LLEAD+ AHQDR+
Sbjct: 1 EANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTNVQNLQKKHALLEADVAAHQDRID 60
Query: 2268 EMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDD 2089
+ QA + F + I ++++ + RY+ +K+ R+ KL+ +L + Q FRD++D
Sbjct: 61 GVTIQARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKLADSLRLQQLFRDVED 120
Query: 2088 EESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAA 1909
EE+WI+EK+ + +S + G+DL GVQNL +KH+ + E+A HEP++ V KG ++
Sbjct: 121 EETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVE--- 177
Query: 1908 EAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQI 1729
E + +K ++ +L Q W ++ R Q L++S Q + D E E+WM EK+ I
Sbjct: 178 EGHFAAEDVKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPI 237
Query: 1728 LGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCD 1549
+GS ++G++ + LLKKH+ DL + + L + + AP +
Sbjct: 238 VGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSC---RQQVAPTDDETGK 294
Query: 1548 QLRARLIEIE-------SMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFG 1390
+L L + + +M +G + L +++ + WK +V + V+ D
Sbjct: 295 ELVLALYDYQEKSPREVTMKKGDILTLLNSTN--KDWWKVEVNDRQGFVPAAYVKKLDPA 352
Query: 1389 RDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRW 1210
+ S +L +E L + + RIT +++ ++ R V + +
Sbjct: 353 QSASRENLL---EEQGSIALRQEQIDNQTRIT-----------KEAGSVSLRMKQVEELY 398
Query: 1209 QNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEE 1030
+LL E R+ + ++ F ++A+ W E LT LE+
Sbjct: 399 HSLLELGEKRKGMLEKSC-------KKFMLF-REANELQQWINEKEAALTSEEVGADLEQ 450
Query: 1029 IRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKS----------------FNVGP----- 913
+ L+ +FQ+ L + E + + + ++S + + P
Sbjct: 451 VEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYGMMPRDETD 510
Query: 912 ----NPY-----------TWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRRE 778
+P+ T+ ++ L + WR+LQ++ +ER Q L H+ Q
Sbjct: 511 SKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQ--------R 562
Query: 777 FAKLANAFHAWLTNTRQEM-MEAGGTLEEQLDAVERK----AKEIKANKGQLRQIEEKGA 613
F + A+ W+ Q + + G + A++RK +++ A ++ + E
Sbjct: 563 FHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAE 622
Query: 612 MLERNLILDNRYTEHSTVGIAQAWDQLDQLA 520
L ++ + + QAW L + A
Sbjct: 623 RLTQSHPESAEDLQEKCTELNQAWSSLGKRA 653
Score = 235 bits (600), Expect = 1e-59
Identities = 203/923 (21%), Positives = 385/923 (40%), Gaps = 37/923 (4%)
Frame = -1
Query: 3384 QRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQF 3205
Q+F + D+ W+ + ++S + D+T + L ++H ++ +
Sbjct: 6 QQFNRNVEDIELWLYEVEGHLASDDYGKDLTNVQNLQKKHALLEADVAAHQDRIDGVTIQ 65
Query: 3204 GNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWM 3025
Q ++ H+ A +I+ + + + + L++ VAR+ L L LQ +RD E +TW+
Sbjct: 66 ARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKLADSLRLQQLFRDVEDEETWI 125
Query: 3024 SAREAFLAQEDPSGD--NVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPA 2851
+E A + D V++L+KKH+ I E +IK + ++++ H+ +
Sbjct: 126 REKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAED 185
Query: 2850 VTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENY-R 2674
V K ++ +W LK Q+R L +S QQ+ DA+E E+WM EK I +Y +
Sbjct: 186 VKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGK 245
Query: 2673 DPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQW 2494
D + + +K +A ++L A I A+ + + + E L + Q
Sbjct: 246 DEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPTDDETGKELVLALYDYQE 305
Query: 2493 DLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKH 2314
+ T +K L N ++W EV A V+ L
Sbjct: 306 KSPREVTMKKGDILTLLNSTNK--------DWWKVEVN----DRQGFVPAAYVKKLDPAQ 353
Query: 2313 SLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKL 2134
S +++ Q + EQ D+ + G ++ R K + + Y + ++ R+ L
Sbjct: 354 SASRENLLEEQGSIALRQEQIDNQTRITKEAGS-VSLRMKQVEELYHSLLELGEKRKGML 412
Query: 2133 SKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQV 1954
K+ FR+ ++ + WI EK+ ++S++ G DL V+ L++K +L ++E ++
Sbjct: 413 EKSCKKFMLFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANESRL 472
Query: 1953 SLVKLKGEEL----LRSAAEAGVGEDQIKKRM---------------------------- 1870
+ E+L L + V + ++ M
Sbjct: 473 KDINKVAEDLESEGLMAEEVQAVQQQEVYGMMPRDETDSKTASPWKSARLMVHTVATFNS 532
Query: 1869 -EDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAG 1693
++L + W ++ L R Q L + Q F D +E + W+ EK Q L +DN+G ++A
Sbjct: 533 IKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLAS 592
Query: 1692 VQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESM 1513
VQ L +KH+ F+ DL +V L + L + A ++++C +L +
Sbjct: 593 VQALQRKHEGFERDLAALGDKVNSLGETAERLTQSHPESAEDLQEKCTELNQAWSSLGKR 652
Query: 1512 AEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAG 1333
A+ R AKL D+ +F+ + SWI V S++ +D++ + LL + +
Sbjct: 653 ADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTE 712
Query: 1332 LNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXX 1153
++A Q + QL++ H SP I+++ + Q +L RR
Sbjct: 713 IDA-RAGTFQAFEQFGQQLLAHGHYASPEIKQKLDILDQERADLEKAWVQRRMMLDQCL- 770
Query: 1152 XXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAE 973
EL L F + +W E L + +SL+ + AL H +F ++++ E
Sbjct: 771 ------ELQL-FHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQE 823
Query: 972 EDFRQLQDL-DRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEEN 796
E LQ D+ I + + + + L D WR L+ + E+ +L Q
Sbjct: 824 EKIAALQAFADQLIAAGHYAKGDISSRRNEVL-DRWRRLKAQMIEKRSKLGESQTLQ--- 879
Query: 795 DKLRREFAKLANAFHAWLTNTRQ 727
+F++ + AW++ Q
Sbjct: 880 -----QFSRDVDEIEAWISEKLQ 897
Score = 228 bits (582), Expect = 1e-57
Identities = 214/933 (22%), Positives = 393/933 (41%), Gaps = 56/933 (6%)
Frame = -1
Query: 3066 QLFYRDCEQADTWMSAREAFLAQEDPSGD--NVESLIKKHEDFDKAINTQEEKIKGLKLF 2893
Q F R+ E + W+ E LA +D D NV++L KKH + + +++I G+ +
Sbjct: 6 QQFNRNVEDIELWLYEVEGHLASDDYGKDLTNVQNLQKKHALLEADVAAHQDRIDGVTIQ 65
Query: 2892 AESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWM 2713
A H+D+ + +K++ ++ R+ LKE ++ ++ KL +S LQQ RD ++ E W+
Sbjct: 66 ARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKLADSLRLQQLFRDVEDEETWI 125
Query: 2712 TEKFQIAQEENY-RDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGE 2536
EK IA N +D +Q +K QA +AE+ + RI A+ Q GN ++E +
Sbjct: 126 REKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAED 185
Query: 2535 AAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDY 2356
V A+L LN +W+ L +++ L+++ + + + A + E W+ E E ++ S DY
Sbjct: 186 --VKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDY 243
Query: 2355 GKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRY 2176
GKD S E LLKKH L +D+ A+ + + EQA S + Q ++L+ Y
Sbjct: 244 GKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQ--QVAPTDDETGKELVLALY 301
Query: 2175 DGVKKMATDRRDK------LSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQ 2014
D +K + K L + N + +++D + ++ Y + L Q
Sbjct: 302 DYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVPAA--------YVKKLDPAQ 353
Query: 2013 NLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRD 1834
+ R++ L + ++L + + + R EAG + RM+ +E+ + + +
Sbjct: 354 SASREN------LLEEQGSIALRQEQIDNQTRITKEAG----SVSLRMKQVEELYHSLLE 403
Query: 1833 LTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQV 1654
L R L++S + E + W+NEK+ L S+ G ++ V+ L KK D FQ
Sbjct: 404 LGEKRKGMLEKSCKKFMLFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQK 463
Query: 1653 DLELHKQRVADLINKGDTLIHNG------------------------------------N 1582
DL+ ++ R+ D+ + L G
Sbjct: 464 DLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYGMMPRDETDSKTASPWKSARLM 523
Query: 1581 HHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRS 1402
H +L R ++ +AE R L +F D + WI EK Q + +
Sbjct: 524 VHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNT 583
Query: 1401 EDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNV 1222
+++G DL+SVQ L K E F+ L A + + + E ++L S + + ++++ T +
Sbjct: 584 DNYGHDLASVQALQRKHEGFERDLAAL-GDKVNSLGETAERLTQSHPESAEDLQEKCTEL 642
Query: 1221 IQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCN 1042
Q W +L ++ R+ + + SW ++
Sbjct: 643 NQAWSSLGKRADQRKAKLGDSHDLQRFLSDF--------RDLMSWINGIRGLVSSDELAK 694
Query: 1041 SLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRN 862
+ AL + H E + + + F+ + +++ + +P +D L+ +
Sbjct: 695 DVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKQKLDILDQERAD 754
Query: 861 LQRIIKER--------EQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEMMEAGG 706
L++ +R E +L Q EN RE AF NT +
Sbjct: 755 LEKAWVQRRMMLDQCLELQLFHRDCEQAENWMAARE------AF----LNTEDK------ 798
Query: 705 TLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLER---NLILDNRYTEHSTVGIAQAWDQ 535
+ LD+VE K+ + + EEK A L+ LI Y + +
Sbjct: 799 --GDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAAGHYAK------GDISSR 850
Query: 534 LDQLAMRMQHNLEQQIQARNQSGVSEEALREFS 436
+++ R + Q I+ R++ G S + L++FS
Sbjct: 851 RNEVLDRWRRLKAQMIEKRSKLGES-QTLQQFS 882
Score = 136 bits (343), Expect = 7e-30
Identities = 90/373 (24%), Positives = 172/373 (45%), Gaps = 1/373 (0%)
Frame = -1
Query: 7137 SQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENF-RDPSNLQAKIQKHEAFEAE 6961
++ + L A + Q F RDADE WI EK Q +N+ D +++QA +KHE FE +
Sbjct: 547 AEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERD 606
Query: 6960 VQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKL 6781
+ A + +L +T + Q + ++E ++++ EL+ W + KL + L
Sbjct: 607 LAALGDKVNSLGETAERLTQSHPESAEDLQEKCTELNQAWSSLGKRADQRKAKLGDSHDL 666
Query: 6780 LHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQA 6601
F+ +++ WI V+++++ D+ E L + + E+ Q
Sbjct: 667 QRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQF 726
Query: 6600 ADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWI 6421
+L+ GH +I +K D ++ L R+ L ++Q F+RD ++ W+
Sbjct: 727 GQQLLAHGHYASPEIKQKLDILDQERADLEKAWVQRRMMLDQCLELQLFHRDCEQAENWM 786
Query: 6420 GEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEA 6241
++ L+++D G L++V+AL +KHE ++ + E K+ L+ A +L
Sbjct: 787 AAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAAGHYAKGD 846
Query: 6240 IHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAK 6061
I + ++ W LK + ++ L S L +F D ++ +WI + K +DE K
Sbjct: 847 ISSRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISE-KLQTASDESYK 905
Query: 6060 DVAGAEALLESHQ 6022
D ++ + HQ
Sbjct: 906 DPTNIQSKHQKHQ 918
>gi|47211129|emb|CAF90367.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 1589
Score = 921 bits (2380), Expect = 0.0
Identities = 500/998 (50%), Positives = 636/998 (63%), Gaps = 111/998 (11%)
Frame = -1
Query: 5922 VQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGD 5743
V+ +L L EK +LL LWE RR YEQCMDLQLFYRDTEQ + WM+KQEAFL N DLGD
Sbjct: 520 VRVQLGILSEEKEALLNLWEVRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGD 579
Query: 5742 SLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXX 5563
SLDSVE L+KKHEDFEKSL+AQEEKI ALDEFATKLIQ HYA +DVA
Sbjct: 580 SLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAKEDVATRRDALLSRRNA 639
Query: 5562 XXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGKLQKHINF 5383
R AL++S+ Q F RD DE+ SWI EK+ TA D++Y DP+N++GK+QKH F
Sbjct: 640 LHERAQSRRAALEDSFHLQQFFRDSDELKSWINEKMKTATDEAYKDPSNLQGKVQKHQAF 699
Query: 5382 EQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREA 5203
E EL AN++R+D ++ +G+ +++ H+A+ + R+ EA
Sbjct: 700 EAELSANQSRIDALQKSGQDLLERKHYASSEVARRME---------------------EA 738
Query: 5202 GNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHN------ 5041
+QQFNRN+ED+E WL E+EG +AS+DYGKDL SVQNLQKK L+E+D AH
Sbjct: 739 NQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTSVQNLQKKHALLEADVAAHQVHTQHT 798
Query: 5040 ----------------------------------DRVDGIKQLAQQFQEEEHFNAPVIVR 4963
DR+DGI A+QFQE HF+A I R
Sbjct: 799 HSVQTSPALRPQLREGGRGVCVGLLRVDSLISSQDRIDGISIQARQFQEAGHFDADNIRR 858
Query: 4962 KQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLI 4783
KQE L RY +R P+ RK+KL +S + QLFRD+EDE WIREKE +A STNRG+DLI
Sbjct: 859 KQEALGVRYEGVRQPMATRKQKLSDSLRLQQLFRDVEDEETWIREKEPIAASTNRGKDLI 918
Query: 4782 GVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKS 4603
GVQNL+KK QAL AEI H+ +I++V+ M+++GHF +++ KL +L W LK
Sbjct: 919 GVQNLLKKHQALQAEIVGHEPRIKAVTQKGETMVEEGHFAGEDVKVKLTELHGRWDTLKL 978
Query: 4602 KAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLS 4423
KA +R+ DL+DSLQA QY +DANEA++WM EKEPIVGSTDYGKDEDSAEALLKKH AL+S
Sbjct: 979 KASQRKQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKHEALMS 1038
Query: 4422 DL--------------------EAFKGTIEDLRKQASQCKYQEQPMG-QLGRDCVLALYD 4306
DL + F T R+ + Q P + G++ VLALYD
Sbjct: 1039 DLSLRQQHPGPEGAGAVLQGRTQPFTLTGTPARRDPLLEQQQVAPTDDETGKELVLALYD 1098
Query: 4305 YQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIEPGTA-------Q 4147
YQEKSPREV+MKKGD+LTLLN++N+DWWKVEVNDR GFVPAAYVK+++P + +
Sbjct: 1099 YQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRLGFVPAAYVKKLDPNQSSSRENLLE 1158
Query: 4146 QHA-----QQQVN---------SIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLR 4009
+H Q Q+ S+ + ++E+ Y L+ LGE RK LE++CK + L R
Sbjct: 1159 EHGSIALRQDQIENQLVTKEACSVSVRMKQVEELYANLLELGEKRKDMLEKSCKKFMLFR 1218
Query: 4008 EANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALT 3829
EAN+L +WI +E +E+G+DLEQVEVLQKKFDDF+ DLKANE RL+++N++A L
Sbjct: 1219 EANELQQWIHEKEGTLTNEEVGSDLEQVEVLQKKFDDFQKDLKANESRLRDINKVAAELE 1278
Query: 3828 SVG--QTETAVRIRQQIEDL---------------------------NARWRALXXXXXX 3736
S G ET + QQ ++L A + +
Sbjct: 1279 SEGLMAEETPMVQAQQQQELLGAAPGKDEADSKTASPWKNVRLAVQTTANFNTIKQLAED 1338
Query: 3735 XXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAA 3556
LGSAHEVQRFHRD DET++WI+EK+ AL+++++G DL SVQALQRKHEG ERDLAA
Sbjct: 1339 RSHMLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAA 1398
Query: 3555 LGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRF 3376
LGDK+ SL E A RL QSHPEA E I + ELN W+ L +A+ RK+KL +S+D QRF
Sbjct: 1399 LGDKVNSLGETAERLIQSHPEAVEDIKEKCSELNTAWSSLVGRADQRKDKLANSHDLQRF 1458
Query: 3375 LSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQ 3262
LSD+RDLM WI + LVSS+ELA DVTGAEALLERHQ
Sbjct: 1459 LSDFRDLMSWINGIRGLVSSEELAKDVTGAEALLERHQ 1496
Score = 432 bits (1112), Expect = e-119
Identities = 216/402 (53%), Positives = 283/402 (69%)
Frame = -1
Query: 7218 IRILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQ 7039
+++LETA+DI RRQ+VL Y FK+ S +R +LE++ +FQ F+RDA+EL WI EKLQ
Sbjct: 6 VKVLETAEDIQDRRQQVLDRYRRFKELSVMRRQKLEDSYRFQCFRRDAEELEKWIQEKLQ 65
Query: 7038 TAQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLE 6859
A +EN++DPSNLQ K+QKH+AFEAEVQA+A TI LD+TGN MI HFASE I+ RLE
Sbjct: 66 IASDENYKDPSNLQGKLQKHQAFEAEVQANAGTIIKLDETGNLMISEGHFASETIRSRLE 125
Query: 6858 ELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVE 6679
ELH LW KG++L QA KL+ ++R+C++ L WI +KE T+E++G DLEHVE
Sbjct: 126 ELHRLWDLLLQKTKEKGLRLLQAQKLVQYLRECEDALDWISDKEAMATSEELGQDLEHVE 185
Query: 6678 ILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAA 6499
+LQ+KF++F +L H+ R+NE+NQ A KL++E H E + I +K+D+VN AW RL LA
Sbjct: 186 LLQKKFEEFQTDLAAHEERVNEVNQLAAKLIQESHPEVELIVRKQDEVNAAWQRLKGLAQ 245
Query: 6498 TRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLA 6319
R+ LFGA +VQRFNRD DET++WI E+ + SDD+GRD +VQAL RKHEG ERDLA
Sbjct: 246 QRQGRLFGAAEVQRFNRDVDETISWIKERGALIGSDDFGRDPGSVQALLRKHEGLERDLA 305
Query: 6318 ALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHR 6139
ALE K+ L +A +L ETHP A I K D+ A W ++ A R
Sbjct: 306 ALEDKVNTLGGDAGRLQETHPQNASQILLKKDELVANWEQIRTLAADATPAWTTPTGEPR 365
Query: 6138 FLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHK 6013
F AD+RDL SW+ +M+A+I ADELA DVAGAEALL+ HQEHK
Sbjct: 366 FTADFRDLTSWVTEMQALIKADELANDVAGAEALLDRHQEHK 407
Score = 398 bits (1023), Expect = e-109
Identities = 261/805 (32%), Positives = 405/805 (49%), Gaps = 67/805 (8%)
Frame = -1
Query: 3141 VNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQED--PSGDNVES 2968
++E ++ L + W RR +QC++LQLFYRD EQ D WMS +EAFL ED S D+VE+
Sbjct: 527 LSEEKEALLNLWEVRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEA 586
Query: 2967 LIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQ 2788
L+KKHEDF+K+++ QEEKI L FA LI+NNHY V +RD +L R N L E
Sbjct: 587 LLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAKEDVATRRDALLSRRNALHERAQS 646
Query: 2787 KRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHAN 2608
+R L +S LQQF RD+DE+++W+ EK + A +E Y+DP+N+Q K QK QAFEAEL AN
Sbjct: 647 RRAALEDSFHLQQFFRDSDELKSWINEKMKTATDEAYKDPSNLQGKVQKHQAFEAELSAN 706
Query: 2607 SDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKS 2428
RI A+ ++G +L+E E A R++EAN+Q+
Sbjct: 707 QSRIDALQKSGQDLLERKHYASSEVA-----------------------RRMEEANQQQQ 743
Query: 2427 FMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAH------------ 2284
F V+D+E WL EVE L S+DYGKDL SV+NL KKH+LLEAD+ AH
Sbjct: 744 FNRNVEDIELWLYEVEGHLASDDYGKDLTSVQNLQKKHALLEADVAAHQVHTQHTHSVQT 803
Query: 2283 ----------------------------QDRVGEMNEQADSLLENDQFQGQQIAERRKLI 2188
QDR+ ++ QA E F I +++ +
Sbjct: 804 SPALRPQLREGGRGVCVGLLRVDSLISSQDRIDGISIQARQFQEAGHFDADNIRRKQEAL 863
Query: 2187 ADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNL 2008
RY+GV++ R+ KLS +L + Q FRD++DEE+WI+EK+ + +S + G+DL GVQNL
Sbjct: 864 GVRYEGVRQPMATRKQKLSDSLRLQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNL 923
Query: 2007 RRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLT 1828
+KH+ + E+ HEP++ V KGE ++ AG + +K ++ +L W ++
Sbjct: 924 LKKHQALQAEIVGHEPRIKAVTQKGETMVEEGHFAG---EDVKVKLTELHGRWDTLKLKA 980
Query: 1827 GNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDL 1648
R Q L++S Q + D E E+WM EK+ I+GS ++G++ + LLKKH+ DL
Sbjct: 981 SQRKQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDL 1040
Query: 1647 ELHKQRV----ADLINKGDTL-------------IHNGNHHAPHIKQRCDQLRARLIEIE 1519
L +Q A + +G T + AP + +L L + +
Sbjct: 1041 SLRQQHPGPEGAGAVLQGRTQPFTLTGTPARRDPLLEQQQVAPTDDETGKELVLALYDYQ 1100
Query: 1518 -------SMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILL 1360
+M +G + L +++ + WK +V + V+ D + S +L
Sbjct: 1101 EKSPREVTMKKGDILTLLNSTN--KDWWKVEVNDRLGFVPAAYVKKLDPNQSSSRENLL- 1157
Query: 1359 TKQEAFDAGLNAFEHEGIQ-RITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEA 1183
EH I R ++++QLV+ E + ++ R V + + NLL E
Sbjct: 1158 ------------EEHGSIALRQDQIENQLVTKE---ACSVSVRMKQVEELYANLLELGEK 1202
Query: 1182 RRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHG 1003
R+ + ++ F ++A+ W E LT+ + LE++ L+
Sbjct: 1203 RKDMLEKSC-------KKFMLF-REANELQQWIHEKEGTLTNEEVGSDLEQVEVLQKKFD 1254
Query: 1002 EFQRSLSSAEEDFRQLQDLDRRIKS 928
+FQ+ L + E R + + ++S
Sbjct: 1255 DFQKDLKANESRLRDINKVAAELES 1279
Score = 282 bits (722), Expect = 8e-74
Identities = 234/966 (24%), Positives = 421/966 (43%), Gaps = 86/966 (8%)
Frame = -1
Query: 3816 TETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALD 3637
+ V +R Q+ L+ AL Q ++Q F+RD ++ +W+ +++ L
Sbjct: 514 SRVCVCVRVQLGILSEEKEALLNLWEVRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLL 573
Query: 3636 SEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQREL 3457
+ED G L SV+AL +KHE E+ L+A +KI +LDE A +L Q++ A E + + L
Sbjct: 574 NEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAKEDVATRRDAL 633
Query: 3456 NEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEAL 3277
+ N L +A +R+ L DS+ Q+F D +L WI + ++ E D + +
Sbjct: 634 LSRRNALHERAQSRRAALEDSFHLQQFFRDSDELKSWI-NEKMKTATDEAYKDPSNLQGK 692
Query: 3276 LERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVAR 3097
+++HQ + E+ + + A + G LL HYA+ ++ R++ N+
Sbjct: 693 VQKHQAFEAELSANQSRIDALQKSGQDLLERKHYASSEVARRMEEANQQ----------- 741
Query: 3096 RNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGD--NVESLIKKHE--DFDKA-- 2935
Q F R+ E + W+ E LA +D D +V++L KKH + D A
Sbjct: 742 ----------QQFNRNVEDIELWLYEVEGHLASDDYGKDLTSVQNLQKKHALLEADVAAH 791
Query: 2934 -INTQ-----------------------------------EEKIKGLKLFAESLIKNNHY 2863
++TQ +++I G+ + A + H+
Sbjct: 792 QVHTQHTHSVQTSPALRPQLREGGRGVCVGLLRVDSLISSQDRIDGISIQARQFQEAGHF 851
Query: 2862 DSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEE 2683
D+ + RK++ + R+ G+++ + ++ KL +S LQQ RD ++ E W+ EK IA
Sbjct: 852 DADNIRRKQEALGVRYEGVRQPMATRKQKLSDSLRLQQLFRDVEDEETWIREKEPIAAST 911
Query: 2682 NY-RDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKAL 2506
N +D +Q +K QA +AE+ + RI A+ Q G ++E G + V +L L
Sbjct: 912 NRGKDLIGVQNLLKKHQALQAEIVGHEPRIKAVTQKGETMVEEGHFAGED--VKVKLTEL 969
Query: 2505 NDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENL 2326
+ +WD L +++ L+++ + + + A + E W+ E E ++ S DYGKD S E L
Sbjct: 970 HGRWDTLKLKASQRKQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEAL 1029
Query: 2325 LKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDR 2146
LKKH L +D+ Q G A F RR + + ++
Sbjct: 1030 LKKHEALMSDLSLRQQHPGPEGAGAVLQGRTQPFTLTGTPARRDPLLE-----QQQVAPT 1084
Query: 2145 RDKLSKALNVHQF-FRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELAS 1969
D+ K L + + +++ E +K+ +L + +D V+ R +
Sbjct: 1085 DDETGKELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRLGFVPAAYVKK 1144
Query: 1968 HEPQVSLVKLKGEELLRSAAEAGVGEDQIKK------------RMEDLEQSWGQIRDLTG 1825
+P S + E LL + +DQI+ RM+ +E+ + + +L
Sbjct: 1145 LDPNQSSSR---ENLLEEHGSIALRQDQIENQLVTKEACSVSVRMKQVEELYANLLELGE 1201
Query: 1824 NRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLE 1645
R L++S + E + W++EK+ L ++ G ++ V+ L KK D FQ DL+
Sbjct: 1202 KRKDMLEKSCKKFMLFREANELQQWIHEKEGTLTNEEVGSDLEQVEVLQKKFDDFQKDLK 1261
Query: 1644 LHKQRVADLINKGDTLIHNG--NHHAPHI--------------KQRCD------------ 1549
++ R+ D+ L G P + K D
Sbjct: 1262 ANESRLRDINKVAAELESEGLMAEETPMVQAQQQQELLGAAPGKDEADSKTASPWKNVRL 1321
Query: 1548 --QLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSS 1375
Q A I+ +AE R L +F D + WI EK Q + ++++G DL+S
Sbjct: 1322 AVQTTANFNTIKQLAEDRSHMLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLAS 1381
Query: 1374 VQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLA 1195
VQ L K E F+ L A + + + E ++L+ S + I+++ + + W +L+
Sbjct: 1382 VQALQRKHEGFERDLAAL-GDKVNSLGETAERLIQSHPEAVEDIKEKCSELNTAWSSLVG 1440
Query: 1194 HSEARR 1177
++ R+
Sbjct: 1441 RADQRK 1446
Score = 275 bits (703), Expect = 1e-71
Identities = 227/914 (24%), Positives = 401/914 (43%), Gaps = 99/914 (10%)
Frame = -1
Query: 7197 DDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENF 7018
+D+ RR +L + + +Q++R LE++ Q F RD+DEL WI EK++TA +E +
Sbjct: 624 EDVATRRDALLSRRNALHERAQSRRAALEDSFHLQQFFRDSDELKSWINEKMKTATDEAY 683
Query: 7017 RDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWX 6838
+DPSNLQ K+QKH+AFEAE+ A+ I L K+G +++ H+AS + +R+EE
Sbjct: 684 KDPSNLQGKVQKHQAFEAELSANQSRIDALQKSGQDLLERKHYASSEVARRMEE------ 737
Query: 6837 XXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFD 6658
A + F R ++I W+ E E ++ ++D G DL V+ LQ+K
Sbjct: 738 ---------------ANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTSVQNLQKKHA 782
Query: 6657 DFLKELGNHQY----------------------------------------RINEINQAA 6598
++ HQ RI+ I+ A
Sbjct: 783 LLEADVAAHQVHTQHTHSVQTSPALRPQLREGGRGVCVGLLRVDSLISSQDRIDGISIQA 842
Query: 6597 DKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIG 6418
+ E GH + D I +K++ + + + ATRK+ L + ++Q+ RD ++ WI
Sbjct: 843 RQFQEAGHFDADNIRRKQEALGVRYEGVRQPMATRKQKLSDSLRLQQLFRDVEDEETWIR 902
Query: 6417 EKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAI 6238
EK+ +S + G+DL VQ L +KH+ + ++ E ++ + ++ + E E +
Sbjct: 903 EKEPIAASTNRGKDLIGVQNLLKKHQALQAEIVGHEPRIKAVTQKGETMVEEGHFAGEDV 962
Query: 6237 HQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKD 6058
K + W+ LK KA RK LE S Q ++ AD + SW+ + + ++G+ + KD
Sbjct: 963 KVKLTELHGRWDTLKLKASQRKQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKD 1022
Query: 6057 VAGAEALLESH----------QEHKGEIDARADSFNQTASAGQKLVEMGIPESPE---VQ 5917
AEALL+ H Q+H G A A +T Q G P + Q
Sbjct: 1023 EDSAEALLKKHEALMSDLSLRQQHPGPEGAGAVLQGRT----QPFTLTGTPARRDPLLEQ 1078
Query: 5916 EKLEKLDHE--KSSLLGLWE-----ERRILYEQCMDLQLFYRDTEQAETWMNK------- 5779
+++ D E K +L L++ R + ++ L L ++ + W +
Sbjct: 1079 QQVAPTDDETGKELVLALYDYQEKSPREVTMKKGDILTLL--NSTNKDWWKVEVNDRLGF 1136
Query: 5778 -QEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDV 5602
A++ D S S E+L+++H S+A ++++I ++ TK A V
Sbjct: 1137 VPAAYVKKLDPNQS-SSRENLLEEH----GSIALRQDQIE--NQLVTK-------EACSV 1182
Query: 5601 AEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSY-LD 5425
+ R + L++S K+ R+ +E+ WI EK T ++ D
Sbjct: 1183 SVRMKQVEELYANLLELGEKRKDMLEKSCKKFMLFREANELQQWIHEKEGTLTNEEVGSD 1242
Query: 5424 PTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNL---- 5257
+ +K +F+++LKANE+RL DI ++ G A + + +Q L
Sbjct: 1243 LEQVEVLQKKFDDFQKDLKANESRLRDINKVAAELESEGLMAEETPMVQAQQQQELLGAA 1302
Query: 5256 --------------------------WNELVDATNKKGAKLREAGNEQQFNRNIEDVEAW 5155
+N + + L A Q+F+R+ ++ + W
Sbjct: 1303 PGKDEADSKTASPWKNVRLAVQTTANFNTIKQLAEDRSHMLGSAHEVQRFHRDADETKEW 1362
Query: 5154 LSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAP 4975
+ E + +++YG DL SVQ LQ+K E D A D+V+ + + A++ +
Sbjct: 1363 IEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAERLIQSHPEAVE 1422
Query: 4974 VIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRG 4795
I K L +++L ++RK KL SH + D D ++WI + S
Sbjct: 1423 DIKEKCSELNTAWSSLVGRADQRKDKLANSHDLQRFLSDFRDLMSWINGIRGLVSSEELA 1482
Query: 4794 RDLIGVQNLIKKQQ 4753
+D+ G + L+++ Q
Sbjct: 1483 KDVTGAEALLERHQ 1496
Score = 268 bits (686), Expect = 1e-69
Identities = 241/1022 (23%), Positives = 428/1022 (41%), Gaps = 60/1022 (5%)
Frame = -1
Query: 6465 VQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEK 6286
+Q F RD ++ W+ +++ L ++D G L++V+AL +KHE E+ L+A E K+ L++
Sbjct: 551 LQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDE 610
Query: 6285 EAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISW 6106
A KL + + E + + D + NAL E+AQ R+ LE SF L +F D +L SW
Sbjct: 611 FATKLIQNNHYAKEDVATRRDALLSRRNALHERAQSRRAALEDSFHLQQFFRDSDELKSW 670
Query: 6105 IGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESP 5926
I + K DE KD + + ++ HQ + E+ A + +GQ L+E S
Sbjct: 671 INE-KMKTATDEAYKDPSNLQGKVQKHQAFEAELSANQSRIDALQKSGQDLLERKHYASS 729
Query: 5925 EVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLG 5746
EV ++E+ + + Q F R+ E E W+ + E LA+ D G
Sbjct: 730 EVARRMEEANQQ---------------------QQFNRNVEDIELWLYEVEGHLASDDYG 768
Query: 5745 DSLDSVEHLIKKHEDFEKSLAA-------------------------------------- 5680
L SV++L KKH E +AA
Sbjct: 769 KDLTSVQNLQKKHALLEADVAAHQVHTQHTHSVQTSPALRPQLREGGRGVCVGLLRVDSL 828
Query: 5679 --QEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQ 5506
+++I+ + A + + H+ AD++ R L +S + Q
Sbjct: 829 ISSQDRIDGISIQARQFQEAGHFDADNIRRKQEALGVRYEGVRQPMATRKQKLSDSLRLQ 888
Query: 5505 TFDRDCDEMVSWITEKLSTARDDSY-LDPTNIRGKLQKHINFEQELKANENRLDDIRSTG 5329
RD ++ +WI EK A + D ++ L+KH + E+ +E R+ + G
Sbjct: 889 QLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIVGHEPRIKAVTQKG 948
Query: 5328 EQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLS 5149
E +++ GHFA + + +L +++ W+ L +++ L ++ QQ+ + + E+W+
Sbjct: 949 ETMVEEGHFAGEDVKVKLTELHGRWDTLKLKASQRKQDLEDSLQAQQYFADANEAESWMR 1008
Query: 5148 ELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVI 4969
E E V S DYGKD S + L KK + SD + L QQ E A +
Sbjct: 1009 EKEPIVGSTDYGKDEDSAEALLKKHEALMSDLS-----------LRQQHPGPEGAGAVLQ 1057
Query: 4968 VRKQENLQQRYNALRDP-LEKRKRKLGESHQGNQLFRDIED-ELAWIREKEQVAG----- 4810
R Q A RDP LE+++ + G +L + D + RE G
Sbjct: 1058 GRTQPFTLTGTPARRDPLLEQQQVAPTDDETGKELVLALYDYQEKSPREVTMKKGDILTL 1117
Query: 4809 --STNRG------RDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFL--- 4663
STN+ D +G ++ + ++ ++ +E S A Q + L
Sbjct: 1118 LNSTNKDWWKVEVNDRLGFVPAAYVKKLDPNQSSSRENLLEEHGSIALRQDQIENQLVTK 1177
Query: 4662 -APEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGST 4486
A + ++ Q+ + + L EKR+ L+ S + +ANE W+ EKE + +
Sbjct: 1178 EACSVSVRMKQVEELYANLLELGEKRKDMLEKSCKKFMLFREANELQQWIHEKEGTLTNE 1237
Query: 4485 DYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQPMGQLGRDCVLALYD 4306
+ G D + E L KK DL+A + + D+ K A+ +L + ++A
Sbjct: 1238 EVGSDLEQVEVLQKKFDDFQKDLKANESRLRDINKVAA----------ELESEGLMA--- 1284
Query: 4305 YQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIEPGTAQQHAQQQV 4126
E++P + ++ ++L G P + + ++ + V
Sbjct: 1285 --EETPMVQAQQQQELL-------------------GAAPGKDEADSKTASPWKNVRLAV 1323
Query: 4125 NSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEI 3946
+ + + L E R L A + + R+A++ EWI+ +
Sbjct: 1324 QTTA--------NFNTIKQLAEDRSHMLGSAHEVQRFHRDADETKEWIEEKNQALNTDNY 1375
Query: 3945 GTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNAR 3766
G DL V+ LQ+K + F+ DL A ++ + + A L E I+++ +LN
Sbjct: 1376 GHDLASVQALQRKHEGFERDLAALGDKVNSLGETAERLIQ-SHPEAVEDIKEKCSELNTA 1434
Query: 3765 WRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRK 3586
W +L +L ++H++QRF D + WI + SE+ +D+ +AL +
Sbjct: 1435 WSSLVGRADQRKDKLANSHDLQRFLSDFRDLMSWINGIRGLVSSEELAKDVTGAEALLER 1494
Query: 3585 HE 3580
H+
Sbjct: 1495 HQ 1496
Score = 256 bits (655), Expect = 4e-66
Identities = 232/991 (23%), Positives = 428/991 (42%), Gaps = 69/991 (6%)
Frame = -1
Query: 4098 IEDKYQRLMMLGETRKRKLEEACKGYQLL-REANDLAEWIKSREAVAAQQEIGTDLEQVE 3922
+ ++ + L+ L E R+++ E+ C QL R+ + W+ +EA +++G L+ VE
Sbjct: 527 LSEEKEALLNLWEVRRQQYEQ-CMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVE 585
Query: 3921 VLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQ-TETAVRIRQQIEDLNARWRALXXX 3745
L KK +DF+ L A E ++ +++ AT L + V R+ + L +R AL
Sbjct: 586 ALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAKEDVATRR--DALLSRRNALHER 643
Query: 3744 XXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERD 3565
L + +Q+F RD DE + WI EK E + +D ++Q +KH+ E +
Sbjct: 644 AQSRRAALEDSFHLQQFFRDSDELKSWINEKMKTATDEAY-KDPSNLQGKVQKHQAFEAE 702
Query: 3564 LAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQ--WNRLTSKAN---NRKEKLL 3400
L+A +I +L + L + A+ ++ E N+Q +NR E L
Sbjct: 703 LSANQSRIDALQKSGQDLLERKHYASSEVARRMEEANQQQQFNRNVEDIELWLYEVEGHL 762
Query: 3399 DSYDYQRFLSDYRDLMQWIASMNQLVSSQEL----ANDVTGAEALLERHQEYRT------ 3250
S DY + L+ ++L + A + V++ ++ + V + AL + +E
Sbjct: 763 ASDDYGKDLTSVQNLQKKHALLEADVAAHQVHTQHTHSVQTSPALRPQLREGGRGVCVGL 822
Query: 3249 -EIDSRAATFQAFDQFG---NQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILD 3082
+DS ++ D Q + H+ A +I + + + +G+ R+ L
Sbjct: 823 LRVDSLISSQDRIDGISIQARQFQEAGHFDADNIRRKQEALGVRYEGVRQPMATRKQKLS 882
Query: 3081 QCLELQLFYRDCEQADTWMSAREAFLAQEDPSGD--NVESLIKKHEDFDKAINTQEEKIK 2908
L LQ +RD E +TW+ +E A + D V++L+KKH+ I E +IK
Sbjct: 883 DSLRLQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIVGHEPRIK 942
Query: 2907 GLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADE 2728
+ E++++ H+ V K ++ RW+ LK Q++ L +S QQ+ DA+E
Sbjct: 943 AVTQKGETMVEEGHFAGEDVKVKLTELHGRWDTLKLKASQRKQDLEDSLQAQQYFADANE 1002
Query: 2727 IENWMTEKFQIAQEENY-RDPTNIQQKHQKQQAFEAEL-----HANSDRIAAIIQAGNNL 2566
E+WM EK I +Y +D + + +K +A ++L H + A++Q
Sbjct: 1003 AESWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSLRQQHPGPEGAGAVLQGRTQP 1062
Query: 2565 IENAKCGGGEAAVSARLKALNDQWDLL-VKTTTEKSYRLKEANKQKSFMAAVKDLEFWLG 2389
AR L +Q + T K L + Q+ + +++ G
Sbjct: 1063 FTLT-------GTPARRDPLLEQQQVAPTDDETGKELVLALYDYQEK---SPREVTMKKG 1112
Query: 2388 EVEILLQSEDYGKDLASVE-----NLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQF 2224
++ LL S + KD VE + + + D R + E L DQ
Sbjct: 1113 DILTLLNSTN--KDWWKVEVNDRLGFVPAAYVKKLDPNQSSSRENLLEEHGSIALRQDQI 1170
Query: 2223 QGQQIAE-------RRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEK 2065
+ Q + + R K + + Y + ++ R+D L K+ FR+ ++ + WI EK
Sbjct: 1171 ENQLVTKEACSVSVRMKQVEELYANLLELGEKRKDMLEKSCKKFMLFREANELQQWIHEK 1230
Query: 2064 KLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLV-----KLKGEELLRSAAE-- 1906
+ +++++ G DL V+ L++K +L ++E ++ + +L+ E L+
Sbjct: 1231 EGTLTNEEVGSDLEQVEVLQKKFDDFQKDLKANESRLRDINKVAAELESEGLMAEETPMV 1290
Query: 1905 ----------AGVGEDQIKKRMED----------LEQSWGQIRDLTGNRHQRLDESEAFQ 1786
A G+D+ + ++ I+ L +R L + Q
Sbjct: 1291 QAQQQQELLGAAPGKDEADSKTASPWKNVRLAVQTTANFNTIKQLAEDRSHMLGSAHEVQ 1350
Query: 1785 AFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKG 1606
F D +E + W+ EK Q L +DN+G ++A VQ L +KH+ F+ DL +V L
Sbjct: 1351 RFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETA 1410
Query: 1605 DTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIA 1426
+ LI + IK++C +L + A+ R KL ++ +F+ + SWI
Sbjct: 1411 ERLIQSHPEAVEDIKEKCSELNTAWSSLVGRADQRKDKLANSHDLQRFLSDFRDLMSWIN 1470
Query: 1425 EKEQQVRSEDFGRDLSSVQILLTKQEAFDAG 1333
V SE+ +D++ + LL + + G
Sbjct: 1471 GIRGLVSSEELAKDVTGAEALLERHQVGGCG 1501
Score = 248 bits (633), Expect = 2e-63
Identities = 137/396 (34%), Positives = 218/396 (54%)
Frame = -1
Query: 2841 KRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTN 2662
+R Q+LDR+ KE + +R KL +S Q F RDA+E+E W+ EK QIA +ENY+DP+N
Sbjct: 18 RRQQVLDRYRRFKELSVMRRQKLEDSYRFQCFRRDAEELEKWIQEKLQIASDENYKDPSN 77
Query: 2661 IQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLV 2482
+Q K QK QAFEAE+ AN+ I + + GN +I + +RL+ L+ WDLL+
Sbjct: 78 LQGKLQKHQAFEAEVQANAGTIIKLDETGNLMISEGHFAS--ETIRSRLEELHRLWDLLL 135
Query: 2481 KTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLE 2302
+ T EK RL +A K ++ +D W+ + E + SE+ G+DL VE L KK +
Sbjct: 136 QKTKEKGLRLLQAQKLVQYLRECEDALDWISDKEAMATSEELGQDLEHVELLQKKFEEFQ 195
Query: 2301 ADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKAL 2122
D+ AH++RV E+N+ A L++ + + I ++ + + +K +A R+ +L A
Sbjct: 196 TDLAAHEERVNEVNQLAAKLIQESHPEVELIVRKQDEVNAAWQRLKGLAQQRQGRLFGAA 255
Query: 2121 NVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVK 1942
V +F RD+D+ SWIKE+ L+ SDD+GRD VQ L RKH ++ +LA+ E +V+ +
Sbjct: 256 EVQRFNRDVDETISWIKERGALIGSDDFGRDPGSVQALLRKHEGLERDLAALEDKVNTL- 314
Query: 1941 LKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEE 1762
G + R QI + ++L +W QIR L + F D +
Sbjct: 315 --GGDAGRLQETHPQNASQILLKKDELVANWEQIRTLAADATPAWTTPTGEPRFTADFRD 372
Query: 1761 EEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQV 1654
+W+ E Q ++ +D ++AG + LL +H +V
Sbjct: 373 LTSWVTEMQALIKADELANDVAGAEALLDRHQEHKV 408
Score = 234 bits (597), Expect = 2e-59
Identities = 125/290 (43%), Positives = 180/290 (61%)
Frame = -1
Query: 4122 SIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIG 3943
+I + E+ + L+ + + +L +A K Q LRE D +WI +EA+A +E+G
Sbjct: 119 TIRSRLEELHRLWDLLLQKTKEKGLRLLQAQKLVQYLRECEDALDWISDKEAMATSEELG 178
Query: 3942 TDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARW 3763
DLE VE+LQKKF++F+ DL A+E R+ E+NQ+A L E + +R+Q +++NA W
Sbjct: 179 QDLEHVELLQKKFEEFQTDLAAHEERVNEVNQLAAKLIQESHPEVELIVRKQ-DEVNAAW 237
Query: 3762 RALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKH 3583
+ L +L A EVQRF+RDVDET WI+E+ + S+DFGRD SVQAL RKH
Sbjct: 238 QRLKGLAQQRQGRLFGAAEVQRFNRDVDETISWIKERGALIGSDDFGRDPGSVQALLRKH 297
Query: 3582 EGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKL 3403
EG+ERDLAAL DK+ +L A RL+++HP+ A QI + EL W ++ + A +
Sbjct: 298 EGLERDLAALEDKVNTLGGDAGRLQETHPQNASQILLKKDELVANWEQIRTLAADATPAW 357
Query: 3402 LDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYR 3253
RF +D+RDL W+ M L+ + ELANDV GAEALL+RHQE++
Sbjct: 358 TTPTGEPRFTADFRDLTSWVTEMQALIKADELANDVAGAEALLDRHQEHK 407
Score = 233 bits (595), Expect = 4e-59
Identities = 204/969 (21%), Positives = 407/969 (41%), Gaps = 84/969 (8%)
Frame = -1
Query: 3459 LNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEA 3280
L+E+ L + R+++ D Q F D + W++ + +++L + + EA
Sbjct: 527 LSEEKEALLNLWEVRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEA 586
Query: 3279 LLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVA 3100
LL++H+++ + ++ A D+F +L+ ++HYA D+ R + R L + +
Sbjct: 587 LLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAKEDVATRRDALLSRRNALHERAQS 646
Query: 3099 RRNILDQCLELQLFYRDCEQADTWMSAREAFLAQE---DPSGDNVESLIKKHEDFDKAIN 2929
RR L+ LQ F+RD ++ +W++ + E DPS N++ ++KH+ F+ ++
Sbjct: 647 RRAALEDSFHLQQFFRDSDELKSWINEKMKTATDEAYKDPS--NLQGKVQKHQAFEAELS 704
Query: 2928 TQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQ 2749
+ +I L+ + L++ HY S V R+ + E+ QQ
Sbjct: 705 ANQSRIDALQKSGQDLLERKHYASSEVARRME---------------------EANQQQQ 743
Query: 2748 FSRDADEIENWMTE-KFQIAQEENYRDPTNIQQKHQKQQAFEAELHANS--DRIAAIIQA 2578
F+R+ ++IE W+ E + +A ++ +D T++Q +K EA++ A+ + +Q
Sbjct: 744 FNRNVEDIELWLYEVEGHLASDDYGKDLTSVQNLQKKHALLEADVAAHQVHTQHTHSVQT 803
Query: 2577 GNNLIENAKCGGGEAAVSA------------------------------------RLKAL 2506
L + GG V + +AL
Sbjct: 804 SPALRPQLREGGRGVCVGLLRVDSLISSQDRIDGISIQARQFQEAGHFDADNIRRKQEAL 863
Query: 2505 NDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENL 2326
+++ + + + +L ++ + + V+D E W+ E E + S + GKDL V+NL
Sbjct: 864 GVRYEGVRQPMATRKQKLSDSLRLQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNL 923
Query: 2325 LKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDR 2146
LKKH L+A+IV H+ R+ + ++ ++++E F G+ + + + R+D +K A+ R
Sbjct: 924 LKKHQALQAEIVGHEPRIKAVTQKGETMVEEGHFAGEDVKVKLTELHGRWDTLKLKASQR 983
Query: 2145 RDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASH 1966
+ L +L Q+F D ++ ESW++EK+ +V S DYG+D + L +KH + ++L+
Sbjct: 984 KQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSLR 1043
Query: 1965 E----PQVSLVKLKGEELLRSAAEAGVGEDQI--KKRMEDLEQSWGQIRDLTGNRHQRLD 1804
+ P+ + L+G + D + ++++ + G+ L +Q
Sbjct: 1044 QQHPGPEGAGAVLQGRTQPFTLTGTPARRDPLLEQQQVAPTDDETGKELVLALYDYQEKS 1103
Query: 1803 ESEAFQAFLGDV------EEEEAWMNEKQQILG------SDNFGENMAGV-QGLLKKHDT 1663
E GD+ ++ W E LG N + + LL++H +
Sbjct: 1104 PREVTMK-KGDILTLLNSTNKDWWKVEVNDRLGFVPAAYVKKLDPNQSSSRENLLEEHGS 1162
Query: 1662 FQVDLELHKQRVAD-LINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLR 1486
+ L + ++ + L+ K A + R Q+ + + E R L
Sbjct: 1163 ----IALRQDQIENQLVTK----------EACSVSVRMKQVEELYANLLELGEKRKDMLE 1208
Query: 1485 DNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEH--E 1312
+ + + ++ WI EKE + +E+ G DL V++L K + F L A E
Sbjct: 1209 KSCKKFMLFREANELQQWIHEKEGTLTNEEVGSDLEQVEVLQKKFDDFQKDLKANESRLR 1268
Query: 1311 GIQRI-TELKDQ--------LVSSEHQQ-----SPAIEKRHTNVIQRWQNL------LAH 1192
I ++ EL+ + +V ++ QQ +P ++ + W+N+ A+
Sbjct: 1269 DINKVAAELESEGLMAEETPMVQAQQQQELLGAAPGKDEADSKTASPWKNVRLAVQTTAN 1328
Query: 1191 SEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRD 1012
+ E+ F + A W E + L + L ++AL+
Sbjct: 1329 FNTIKQLAEDRSHMLGSAHEVQ-RFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQR 1387
Query: 1011 AHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQ 832
H F+R L++ + L + R+ + L W +L +R+
Sbjct: 1388 KHEGFERDLAALGDKVNSLGETAERLIQSHPEAVEDIKEKCSELNTAWSSLVGRADQRKD 1447
Query: 831 ELAREHQRQ 805
+LA H Q
Sbjct: 1448 KLANSHDLQ 1456
Score = 229 bits (584), Expect = 8e-58
Identities = 183/771 (23%), Positives = 341/771 (43%), Gaps = 90/771 (11%)
Frame = -1
Query: 7119 RLEEARQFQYFKRDADELNVWILE-KLQTAQEENFRDPSNLQAKIQKHEAFEAEVQAHA- 6946
R+EEA Q Q F R+ +++ +W+ E + A ++ +D +++Q +KH EA+V AH
Sbjct: 734 RMEEANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTSVQNLQKKHALLEADVAAHQV 793
Query: 6945 ---------------------------------KTIANLDKTGNAMIQHN------HFAS 6883
I++ D+ IQ HF +
Sbjct: 794 HTQHTHSVQTSPALRPQLREGGRGVCVGLLRVDSLISSQDRIDGISIQARQFQEAGHFDA 853
Query: 6882 EHIKKRLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDM 6703
++I+++ E L + + KL +L+L R ++ WIREKE + +
Sbjct: 854 DNIRRKQEALGVRYEGVRQPMATRKQKLSDSLRLQQLFRDVEDEETWIREKEPIAASTNR 913
Query: 6702 GMDLEHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAW 6523
G DL V+ L +K E+ H+ RI + Q + +VEEGH + + K +++ W
Sbjct: 914 GKDLIGVQNLLKKHQALQAEIVGHEPRIKAVTQKGETMVEEGHFAGEDVKVKLTELHGRW 973
Query: 6522 HRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKH 6343
L A+ RK+ L + Q Q++ DA+E +W+ EK+ + S DYG+D ++ +AL +KH
Sbjct: 974 DTLKLKASQRKQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKH 1033
Query: 6342 EGTERDLAALE--------GKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEK 6187
E DL+ + G +LQ + L T P R + + ++ KE
Sbjct: 1034 EALMSDLSLRQQHPGPEGAGAVLQGRTQPFTLTGT-PARRDPLLEQQQVAPTDDETGKEL 1092
Query: 6186 AQHRKDGLERS-FQLHRFLADYRDLIS-----W----IGDMKAVIGADELAKDVAGAEAL 6037
D E+S ++ D L++ W + D + A + K +
Sbjct: 1093 VLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRLGFVPAAYVKKLDPNQSSS 1152
Query: 6036 LESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEER 5857
E+ E G I R D ++ E+ V ++++++ ++LL L E+R
Sbjct: 1153 RENLLEEHGSIALRQDQIEN---------QLVTKEACSVSVRMKQVEELYANLLELGEKR 1203
Query: 5856 RILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQ 5677
+ + E+ + +R+ + + W++++E L N ++G L+ VE L KK +DF+K L A
Sbjct: 1204 KDMLEKSCKKFMLFREANELQQWIHEKEGTLTNEEVGSDLEQVEVLQKKFDDFQKDLKAN 1263
Query: 5676 EEKINALDEFA------------TKLIQGQHY-------AADDVAEXXXXXXXXXXXXXX 5554
E ++ +++ A T ++Q Q D A+
Sbjct: 1264 ESRLRDINKVAAELESEGLMAEETPMVQAQQQQELLGAAPGKDEADSKTASPWKNVRLAV 1323
Query: 5553 XXXXRGNALKE-----------SYKRQTFDRDCDEMVSWITEKLSTARDDSY-LDPTNIR 5410
N +K+ +++ Q F RD DE WI EK D+Y D +++
Sbjct: 1324 QTTANFNTIKQLAEDRSHMLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQ 1383
Query: 5409 GKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATN 5230
+KH FE++L A ++++ + T E++I S A + I ++ ++N W+ LV +
Sbjct: 1384 ALQRKHEGFERDLAALGDKVNSLGETAERLIQSHPEAVEDIKEKCSELNTAWSSLVGRAD 1443
Query: 5229 KKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKK 5077
++ KL + + Q+F + D+ +W++ + G V+SE+ KD+ + L ++
Sbjct: 1444 QRKDKLANSHDLQRFLSDFRDLMSWINGIRGLVSSEELAKDVTGAEALLER 1494
Score = 225 bits (573), Expect = 1e-56
Identities = 134/362 (37%), Positives = 202/362 (55%), Gaps = 32/362 (8%)
Frame = -1
Query: 7011 PSNLQAKIQKHEAFEAE--VQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWX 6838
P+ K+ +++ E ++ H D+ N ++ + K++EEL+A
Sbjct: 1138 PAAYVKKLDPNQSSSRENLLEEHGSIALRQDQIENQLVTKEACSVSVRMKQVEELYANLL 1197
Query: 6837 XXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFD 6658
L+++ K R+ +E+ WI EKE +T E++G DLE VE+LQ+KFD
Sbjct: 1198 ELGEKRKDM---LEKSCKKFMLFREANELQQWIHEKEGTLTNEEVGSDLEQVEVLQKKFD 1254
Query: 6657 DFLKELGNHQYRINEINQAADKLVEEGHSEHD----QIYKKRDDVNDA------------ 6526
DF K+L ++ R+ +IN+ A +L EG + Q ++++ + A
Sbjct: 1255 DFQKDLKANESRLRDINKVAAELESEGLMAEETPMVQAQQQQELLGAAPGKDEADSKTAS 1314
Query: 6525 --------------WHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDD 6388
++ + LA R L AH+VQRF+RDADET WI EK+ AL++D+
Sbjct: 1315 PWKNVRLAVQTTANFNTIKQLAEDRSHMLGSAHEVQRFHRDADETKEWIEEKNQALNTDN 1374
Query: 6387 YGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAA 6208
YG DL +VQALQRKHEG ERDLAAL K+ L + A +L ++HP+ E I +K + A
Sbjct: 1375 YGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAERLIQSHPEAVEDIKEKCSELNTA 1434
Query: 6207 WNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLES 6028
W++L +A RKD L S L RFL+D+RDL+SWI ++ ++ ++ELAKDV GAEALLE
Sbjct: 1435 WSSLVGRADQRKDKLANSHDLQRFLSDFRDLMSWINGIRGLVSSEELAKDVTGAEALLER 1494
Query: 6027 HQ 6022
HQ
Sbjct: 1495 HQ 1496
Score = 222 bits (565), Expect = 1e-55
Identities = 117/365 (32%), Positives = 207/365 (56%)
Frame = -1
Query: 5529 LKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRL 5350
L++SY+ Q F RD +E+ WI EKL A D++Y DP+N++GKLQKH FE E++AN +
Sbjct: 40 LEDSYRFQCFRRDAEELEKWIQEKLQIASDENYKDPSNLQGKLQKHQAFEAEVQANAGTI 99
Query: 5349 DDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIE 5170
+ TG +I GHFA++ I RL +++ LW+ L+ T +KG +L +A Q+ R E
Sbjct: 100 IKLDETGNLMISEGHFASETIRSRLEELHRLWDLLLQKTKEKGLRLLQAQKLVQYLRECE 159
Query: 5169 DVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEE 4990
D W+S+ E SE+ G+DL V+ LQKK ++D AH +RV+ + QLA + +E
Sbjct: 160 DALDWISDKEAMATSEELGQDLEHVELLQKKFEEFQTDLAAHEERVNEVNQLAAKLIQES 219
Query: 4989 HFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAG 4810
H +IVRKQ+ + + L+ ++R+ +L + + + RD+++ ++WI+E+ + G
Sbjct: 220 HPEVELIVRKQDEVNAAWQRLKGLAQQRQGRLFGAAEVQRFNRDVDETISWIKERGALIG 279
Query: 4809 STNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQL 4630
S + GRD VQ L++K + L ++A + ++ ++ A + + A +I K +L
Sbjct: 280 SDDFGRDPGSVQALLRKHEGLERDLAALEDKVNTLGGDAGRLQETHPQNASQILLKKDEL 339
Query: 4629 RDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEAL 4450
NW +++ A ++ +D + +W++E + ++ + + D AEAL
Sbjct: 340 VANWEQIRTLAADATPAWTTPTGEPRFTADFRDLTSWVTEMQALIKADELANDVAGAEAL 399
Query: 4449 LKKHR 4435
L +H+
Sbjct: 400 LDRHQ 404
Score = 218 bits (554), Expect = 2e-54
Identities = 225/992 (22%), Positives = 411/992 (40%), Gaps = 105/992 (10%)
Frame = -1
Query: 4653 IRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGK 4474
+R +L L + L + E RR + + + D + D WMS++E + + D G
Sbjct: 520 VRVQLGILSEEKEALLNLWEVRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGD 579
Query: 4473 DEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQC----KYQEQPMGQLGRDCVLALYD 4306
DS EALLKKH L A + I L + A++ Y ++ + RD +L+ +
Sbjct: 580 SLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAKEDVATR-RDALLSRRN 638
Query: 4305 --YQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIE--PGTAQQH- 4141
++ R +++ L + D K +N++ K G Q+H
Sbjct: 639 ALHERAQSRRAALEDSFHLQQFFRDS-DELKSWINEKMKTATDEAYKDPSNLQGKVQKHQ 697
Query: 4140 ---AQQQVNS--IGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKS 3976
A+ N I Q +D +R R++EEA + Q R D+ W+
Sbjct: 698 AFEAELSANQSRIDALQKSGQDLLERKHYASSEVARRMEEANQQQQFNRNVEDIELWLYE 757
Query: 3975 REAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVR- 3799
E A + G DL V+ LQKK + D+ A++V Q + + T+ Q R
Sbjct: 758 VEGHLASDDYGKDLTSVQNLQKKHALLEADVAAHQVHTQHTHSVQTSPALRPQLREGGRG 817
Query: 3798 --------------------------------------IRQQIEDLNARWRALXXXXXXX 3733
IR++ E L R+ +
Sbjct: 818 VCVGLLRVDSLISSQDRIDGISIQARQFQEAGHFDADNIRRKQEALGVRYEGVRQPMATR 877
Query: 3732 XXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAAL 3553
+L + +Q+ RDV++ WI+EK+ S + G+DL VQ L +KH+ ++ ++
Sbjct: 878 KQKLSDSLRLQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIVGH 937
Query: 3552 GDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFL 3373
+IK++ +K + + A E + EL+ +W+ L KA+ RK+ L DS Q++
Sbjct: 938 EPRIKAVTQKGETMVEEGHFAGEDVKVKLTELHGRWDTLKLKASQRKQDLEDSLQAQQYF 997
Query: 3372 SDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRA------------- 3232
+D + W+ +V S + D AEALL++H+ +++ R
Sbjct: 998 ADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSLRQQHPGPEGAGAVLQ 1057
Query: 3231 ATFQAFDQFG-----NQLLNSHHYAAGDIENRLQGV----NEARKGLEDAWVARRNILDQ 3079
Q F G + LL A D E + V + K + + + +IL
Sbjct: 1058 GRTQPFTLTGTPARRDPLLEQQQVAPTDDETGKELVLALYDYQEKSPREVTMKKGDILTL 1117
Query: 3078 CLELQLFYRDCEQADTWMSAREAFLAQEDPS-GDNVESLIKKHEDFDKAINTQEEKIKGL 2902
+ E D A++ + DP+ + E+L+++H +I ++++I+
Sbjct: 1118 LNSTNKDWWKVEVNDRLGFVPAAYVKKLDPNQSSSRENLLEEHG----SIALRQDQIENQ 1173
Query: 2901 KLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIE 2722
+ E+ +V+ + Q+ + + L E +++ L +S R+A+E++
Sbjct: 1174 LVTKEAC---------SVSVRMKQVEELYANLLELGEKRKDMLEKSCKKFMLFREANELQ 1224
Query: 2721 NWMTEKF-QIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCG 2545
W+ EK + EE D ++ +K F+ +L AN R+ I + L
Sbjct: 1225 QWIHEKEGTLTNEEVGSDLEQVEVLQKKFDDFQKDLKANESRLRDINKVAAELESEGLMA 1284
Query: 2544 GGEAAVSARLKAL-------NDQWD-----------LLVKTTT----------EKSYRLK 2449
V A+ + D+ D L V+TT ++S+ L
Sbjct: 1285 EETPMVQAQQQQELLGAAPGKDEADSKTASPWKNVRLAVQTTANFNTIKQLAEDRSHMLG 1344
Query: 2448 EANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVG 2269
A++ + F + + W+ E L +++YG DLASV+ L +KH E D+ A D+V
Sbjct: 1345 SAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVN 1404
Query: 2268 EMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDD 2089
+ E A+ L+++ + I E+ + + + A R+DKL+ + ++ +F D D
Sbjct: 1405 SLGETAERLIQSHPEAVEDIKEKCSELNTAWSSLVGRADQRKDKLANSHDLQRFLSDFRD 1464
Query: 2088 EESWIKEKKLLVSSDDYGRDLPGVQNLRRKHR 1993
SWI + LVSS++ +D+ G + L +H+
Sbjct: 1465 LMSWINGIRGLVSSEELAKDVTGAEALLERHQ 1496
Score = 185 bits (470), Expect = 1e-44
Identities = 128/529 (24%), Positives = 233/529 (43%), Gaps = 41/529 (7%)
Frame = -1
Query: 7134 QTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENFRDP-SNLQAKIQKHEAFEAEV 6958
+ +R + E+ Q F RD ++++ W+ ++ E+ D +++A ++KHE FE +
Sbjct: 539 EVRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEALLKKHEDFEKSL 598
Query: 6957 QAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKLL 6778
A + I LD+ +IQ+NH+A E + R + L + + L+ + L
Sbjct: 599 SAQEEKITALDEFATKLIQNNHYAKEDVATRRDALLSRRNALHERAQSRRAALEDSFHLQ 658
Query: 6777 HFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQAA 6598
F R DE+ WI EK T ++ D +++ +K F EL +Q RI+ + ++
Sbjct: 659 QFFRDSDELKSWINEKMKTAT-DEAYKDPSNLQGKVQKHQAFEAELSANQSRIDALQKSG 717
Query: 6597 DKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIG 6418
L+E H ++ ++ ++ N Q Q+FNR+ ++ W+
Sbjct: 718 QDLLERKHYASSEVARRMEEAN---------------------QQQQFNRNVEDIELWLY 756
Query: 6417 EKDLALSSDDYGRDLNNVQALQRKHEGTERDLAA-------------------------- 6316
E + L+SDDYG+DL +VQ LQ+KH E D+AA
Sbjct: 757 EVEGHLASDDYGKDLTSVQNLQKKHALLEADVAAHQVHTQHTHSVQTSPALRPQLREGGR 816
Query: 6315 --------------LEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQH 6178
+ ++ + +A + E A+ I +K + + +++
Sbjct: 817 GVCVGLLRVDSLISSQDRIDGISIQARQFQEAGHFDADNIRRKQEALGVRYEGVRQPMAT 876
Query: 6177 RKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDA 5998
RK L S +L + D D +WI + + + + KD+ G + LL+ HQ + EI
Sbjct: 877 RKQKLSDSLRLQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIVG 936
Query: 5997 RADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLF 5818
G+ +VE G +V+ KL +L +L +R+ E + Q +
Sbjct: 937 HEPRIKAVTQKGETMVEEGHFAGEDVKVKLTELHGRWDTLKLKASQRKQDLEDSLQAQQY 996
Query: 5817 YRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEE 5671
+ D +AE+WM ++E + +TD G DS E L+KKHE L+ +++
Sbjct: 997 FADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSLRQQ 1045
Score = 169 bits (427), Expect = 1e-39
Identities = 105/397 (26%), Positives = 198/397 (49%), Gaps = 3/397 (0%)
Frame = -1
Query: 3495 EAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSS 3316
E AE I D ++++ +++ R + R++KL DSY +Q F D +L +WI Q ++S
Sbjct: 10 ETAEDIQDRRQQVLDRYRRFKELSVMRRQKLEDSYRFQCFRRDAEELEKWIQEKLQ-IAS 68
Query: 3315 QELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVN 3136
E D + + L++HQ + E+ + A T D+ GN +++ H+A+ I +RL+ ++
Sbjct: 69 DENYKDPSNLQGKLQKHQAFEAEVQANAGTIIKLDETGNLMISEGHFASETIRSRLEELH 128
Query: 3135 EARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGD--NVESLI 2962
L + L Q +L + R+CE A W+S +EA E+ D +VE L
Sbjct: 129 RLWDLLLQKTKEKGLRLLQAQKLVQYLRECEDALDWISDKEAMATSEELGQDLEHVELLQ 188
Query: 2961 KKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKR 2782
KK E+F + EE++ + A LI+ +H + + RK+D++ W LK Q++
Sbjct: 189 KKFEEFQTDLAAHEERVNEVNQLAAKLIQESHPEVELIVRKQDEVNAAWQRLKGLAQQRQ 248
Query: 2781 FKLGESQTLQQFSRDADEIENWMTEKFQIAQEENY-RDPTNIQQKHQKQQAFEAELHANS 2605
+L + +Q+F+RD DE +W+ E+ + +++ RDP ++Q +K + E +L A
Sbjct: 249 GRLFGAAEVQRFNRDVDETISWIKERGALIGSDDFGRDPGSVQALLRKHEGLERDLAALE 308
Query: 2604 DRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSF 2425
D++ + L E + + + L W+ + + + + F
Sbjct: 309 DKVNTLGGDAGRLQETHPQNASQ--ILLKKDELVANWEQIRTLAADATPAWTTPTGEPRF 366
Query: 2424 MAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKH 2314
A +DL W+ E++ L+++++ D+A E LL +H
Sbjct: 367 TADFRDLTSWVTEMQALIKADELANDVAGAEALLDRH 403
Score = 168 bits (426), Expect = 2e-39
Identities = 185/837 (22%), Positives = 348/837 (41%), Gaps = 49/837 (5%)
Frame = -1
Query: 2529 VSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGK 2350
V +L L+++ + L+ + + ++ + F + ++ W+ + E L +ED G
Sbjct: 520 VRVQLGILSEEKEALLNLWEVRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGD 579
Query: 2349 DLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDG 2170
L SVE LLKKH E + A ++++ ++E A L++N+ + + +A RR + R +
Sbjct: 580 SLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAKEDVATRRDALLSRRNA 639
Query: 2169 VKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRR 1990
+ + A RR L + ++ QFFRD D+ +SWI E K+ ++D+ +D +Q +KH+
Sbjct: 640 LHERAQSRRAALEDSFHLQQFFRDSDELKSWINE-KMKTATDEAYKDPSNLQGKVQKHQA 698
Query: 1989 IDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQR 1810
+ EL++++ ++ ++ G++LL A ++ +RME+ Q
Sbjct: 699 FEAELSANQSRIDALQKSGQDLLERKHYA---SSEVARRMEEANQQ-------------- 741
Query: 1809 LDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHK-- 1636
Q F +VE+ E W+ E + L SD++G+++ VQ L KKH + D+ H+
Sbjct: 742 -------QQFNRNVEDIELWLYEVEGHLASDDYGKDLTSVQNLQKKHALLEADVAAHQVH 794
Query: 1635 ----------------------------QRVADLINKGDTL----------IHNGNHHAP 1570
RV LI+ D + G+ A
Sbjct: 795 TQHTHSVQTSPALRPQLREGGRGVCVGLLRVDSLISSQDRIDGISIQARQFQEAGHFDAD 854
Query: 1569 HIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFG 1390
+I+++ + L R + R KL D+ Q + E+WI EKE S + G
Sbjct: 855 NIRRKQEALGVRYEGVRQPMATRKQKLSDSLRLQQLFRDVEDEETWIREKEPIAASTNRG 914
Query: 1389 RDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRW 1210
+DL VQ LL K +A A + E I+ +T+ + +V H ++ + T + RW
Sbjct: 915 KDLIGVQNLLKKHQALQAEIVGHEPR-IKAVTQKGETMVEEGHFAGEDVKVKLTELHGRW 973
Query: 1209 QNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEE 1030
L + R+ + Y A A +A SW E + +
Sbjct: 974 DTLKLKASQRKQDLEDSLQA-----QQYFADANEA---ESWMREKEPIVGSTDYGKDEDS 1025
Query: 1029 IRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVG-PNPYTWFTMDALEDTWRNLQR 853
AL H LS RQ + G P+T A D Q+
Sbjct: 1026 AEALLKKHEALMSDLS-----LRQQHPGPEGAGAVLQGRTQPFTLTGTPARRDPLLEQQQ 1080
Query: 852 IIKEREQELARE--HQRQEENDKLRREFAKLANAFHAWLTNTRQEMMEAGGTLEEQLDAV 679
+ + E +E + +K RE L +T ++ + + ++L V
Sbjct: 1081 -VAPTDDETGKELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKV--EVNDRLGFV 1137
Query: 678 ERK-AKEIKANKGQLRQ--IEEKGAMLERNLILDNRYTEHSTVGIAQAWDQLDQLAMRMQ 508
K++ N+ R+ +EE G++ R ++N+ ++ Q+++L +
Sbjct: 1138 PAAYVKKLDPNQSSSRENLLEEHGSIALRQDQIENQLVTKEACSVSVRMKQVEELYANLL 1197
Query: 507 HNLEQQIQARNQSGVSEEALREFSMMFKHFDKEKTGRLDHQQFKSCLRALGYDLPMVDEG 328
E++ +S RE + + + + EK G L +++ +G DL V+
Sbjct: 1198 ELGEKRKDMLEKSCKKFMLFREANEL-QQWIHEKEGTLTNEE-------VGSDLEQVEVL 1249
Query: 327 QPE-PEFQRILDIVDPN-RD-GYVTLQEYMAFMISKETENIQSSEEIEMAFRALSKE 166
Q + +FQ+ L + RD V + ++++ET +Q+ ++ E+ A K+
Sbjct: 1250 QKKFDDFQKDLKANESRLRDINKVAAELESEGLMAEETPMVQAQQQQELLGAAPGKD 1306
Score = 165 bits (418), Expect = 1e-38
Identities = 150/651 (23%), Positives = 269/651 (41%), Gaps = 48/651 (7%)
Frame = -1
Query: 7200 ADDIHQRRQEVLG-HYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEE 7024
AD+I +R+QE LG Y + T++ +L ++ + Q RD ++ WI EK A
Sbjct: 853 ADNI-RRKQEALGVRYEGVRQPMATRKQKLSDSLRLQQLFRDVEDEETWIREKEPIAAST 911
Query: 7023 NF-RDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHA 6847
N +D +Q ++KH+A +AE+ H I + + G M++ HFA E +K +L ELH
Sbjct: 912 NRGKDLIGVQNLLKKHQALQAEIVGHEPRIKAVTQKGETMVEEGHFAGEDVKVKLTELHG 971
Query: 6846 LWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQR 6667
W + L+ +L+ + +E W+REKE V + D G D + E L +
Sbjct: 972 RWDTLKLKASQRKQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLK 1031
Query: 6666 KFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIY---KKRDDVNDAWHRLNTLAAT 6496
K + + +L Q A V +G ++ + +RD + + T T
Sbjct: 1032 KHEALMSDLSLRQQHPGPEGAGA---VLQGRTQPFTLTGTPARRDPLLEQQQVAPTDDET 1088
Query: 6495 RKEGLFGAHQVQRFNRDADETLAWIGEKDLALSS---DDYGRDLNN---------VQALQ 6352
KE + + Q + E G+ L+S D + ++N+ V+ L
Sbjct: 1089 GKELVLALYDYQ--EKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRLGFVPAAYVKKLD 1146
Query: 6351 RKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRK 6172
+ +L G + + + T + ++ K + + L E + RK
Sbjct: 1147 PNQSSSRENLLEEHGSIALRQDQIENQLVTKEACSVSVRMK--QVEELYANLLELGEKRK 1204
Query: 6171 DGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARA 5992
D LE+S + + +L WI + + + +E+ D+ E L + + + ++ A
Sbjct: 1205 DMLEKSCKKFMLFREANELQQWIHEKEGTLTNEEVGSDLEQVEVLQKKFDDFQKDLKANE 1264
Query: 5991 DSFNQTASAGQKLVEMGI--PESPEVQEKLEK--------LDHEKSSLLGLW-------- 5866
+L G+ E+P VQ + ++ D S W
Sbjct: 1265 SRLRDINKVAAELESEGLMAEETPMVQAQQQQELLGAAPGKDEADSKTASPWKNVRLAVQ 1324
Query: 5865 ------------EERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEH 5722
E+R + ++Q F+RD ++ + W+ ++ L + G L SV+
Sbjct: 1325 TTANFNTIKQLAEDRSHMLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQA 1384
Query: 5721 LIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXX 5542
L +KHE FE+ LAA +K+N+L E A +LIQ A +D+ E
Sbjct: 1385 LQRKHEGFERDLAALGDKVNSLGETAERLIQSHPEAVEDIKEKCSELNTAWSSLVGRADQ 1444
Query: 5541 RGNALKESYKRQTFDRDCDEMVSWITE-KLSTARDDSYLDPTNIRGKLQKH 5392
R + L S+ Q F D +++SWI + + ++ D T L++H
Sbjct: 1445 RKDKLANSHDLQRFLSDFRDLMSWINGIRGLVSSEELAKDVTGAEALLERH 1495
Score = 152 bits (383), Expect = 2e-34
Identities = 96/392 (24%), Positives = 186/392 (46%), Gaps = 1/392 (0%)
Frame = -1
Query: 6564 DQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDY 6385
+ I +R V D + R L+ R++ L +++ Q F RDA+E WI EK L ++SD+
Sbjct: 13 EDIQDRRQQVLDRYRRFKELSVMRRQKLEDSYRFQCFRRDAEELEKWIQEK-LQIASDEN 71
Query: 6384 GRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAW 6205
+D +N+Q +KH+ E ++ A G +++L++ + + +E I + ++ W
Sbjct: 72 YKDPSNLQGKLQKHQAFEAEVQANAGTIIKLDETGNLMISEGHFASETIRSRLEELHRLW 131
Query: 6204 NALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESH 6025
+ L +K + + L ++ +L ++L + D + WI D +A+ ++EL +D+ E L +
Sbjct: 132 DLLLQKTKEKGLRLLQAQKLVQYLRECEDALDWISDKEAMATSEELGQDLEHVELLQKKF 191
Query: 6024 QEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILY 5845
+E + ++ A + N+ KL++ PE + K ++++ L GL ++R+
Sbjct: 192 EEFQTDLAAHEERVNEVNQLAAKLIQESHPEVELIVRKQDEVNAAWQRLKGLAQQRQGRL 251
Query: 5844 EQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKI 5665
++Q F RD ++ +W+ ++ A + + D G SV+ L++KHE E+ LAA E+K+
Sbjct: 252 FGAAEVQRFNRDVDETISWIKERGALIGSDDFGRDPGSVQALLRKHEGLERDLAALEDKV 311
Query: 5664 NALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCD 5485
N L A +L + A + A F D
Sbjct: 312 NTLGGDAGRLQETHPQNASQILLKKDELVANWEQIRTLAADATPAWTTPTGEPRFTADFR 371
Query: 5484 EMVSWITEKLSTARDDSYL-DPTNIRGKLQKH 5392
++ SW+TE + + D D L +H
Sbjct: 372 DLTSWVTEMQALIKADELANDVAGAEALLDRH 403
Score = 150 bits (380), Expect = 3e-34
Identities = 90/394 (22%), Positives = 201/394 (50%)
Frame = -1
Query: 2529 VSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGK 2350
+ R + + D++ + + + +L+++ + + F ++LE W+ E + E+Y K
Sbjct: 15 IQDRRQQVLDRYRRFKELSVMRRQKLEDSYRFQCFRRDAEELEKWIQEKLQIASDENY-K 73
Query: 2349 DLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDG 2170
D ++++ L+KH EA++ A+ + +++E + ++ F + I R + + +D
Sbjct: 74 DPSNLQGKLQKHQAFEAEVQANAGTIIKLDETGNLMISEGHFASETIRSRLEELHRLWDL 133
Query: 2169 VKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRR 1990
+ + ++ +L +A + Q+ R+ +D WI +K+ + +S++ G+DL V+ L++K
Sbjct: 134 LLQKTKEKGLRLLQAQKLVQYLRECEDALDWISDKEAMATSEELGQDLEHVELLQKKFEE 193
Query: 1989 IDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQR 1810
T+LA+HE +V+ V +L++ E+ + I ++ +++ +W +++ L R R
Sbjct: 194 FQTDLAAHEERVNEVNQLAAKLIQ---ESHPEVELIVRKQDEVNAAWQRLKGLAQQRQGR 250
Query: 1809 LDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQR 1630
L + Q F DV+E +W+ E+ ++GSD+FG + VQ LL+KH+ + DL + +
Sbjct: 251 LFGAAEVQRFNRDVDETISWIKERGALIGSDDFGRDPGSVQALLRKHEGLERDLAALEDK 310
Query: 1629 VADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKC 1450
V L L +A I + D+L A +I ++A + +F
Sbjct: 311 VNTLGGDAGRLQETHPQNASQILLKKDELVANWEQIRTLAADATPAWTTPTGEPRFTADF 370
Query: 1449 DVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQE 1348
+ SW+ E + +++++ D++ + LL + +
Sbjct: 371 RDLTSWVTEMQALIKADELANDVAGAEALLDRHQ 404
Score = 149 bits (375), Expect = 1e-33
Identities = 105/420 (25%), Positives = 207/420 (49%), Gaps = 10/420 (2%)
Frame = -1
Query: 6930 LDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEI 6751
+D TG +++ +E I+ R +++ + + KL+ + + F R +E+
Sbjct: 1 MDTTGVKVLE----TAEDIQDRRQQVLDRYRRFKELSVMRRQKLEDSYRFQCFRRDAEEL 56
Query: 6750 LYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHS 6571
WI+EK + +++ D +++ +K F E+ + I ++++ + ++ EGH
Sbjct: 57 EKWIQEK-LQIASDENYKDPSNLQGKLQKHQAFEAEVQANAGTIIKLDETGNLMISEGHF 115
Query: 6570 EHDQIYKKRDDVNDAWHRLNTLAATRKEGL--FGAHQVQRFNRDADETLAWIGEKDLALS 6397
+ I + ++++ W L L T+++GL A ++ ++ R+ ++ L WI +K+ +
Sbjct: 116 ASETIRSRLEELHRLWDLL--LQKTKEKGLRLLQAQKLVQYLRECEDALDWISDKEAMAT 173
Query: 6396 SDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLA-ETHPDRAEAIHQKNDD 6220
S++ G+DL +V+ LQ+K E + DLAA E ++ ++ + A KL E+HP+ E I +K D+
Sbjct: 174 SEELGQDLEHVELLQKKFEEFQTDLAAHEERVNEVNQLAAKLIQESHPE-VELIVRKQDE 232
Query: 6219 TKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEA 6040
AAW LK AQ R+ L + ++ RF D + ISWI + A+IG+D+ +D +A
Sbjct: 233 VNAAWQRLKGLAQQRQGRLFGAAEVQRFNRDVDETISWIKERGALIGSDDFGRDPGSVQA 292
Query: 6039 LLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEE 5860
LL H+ + ++ A D N +L E + ++ K K L+ WE+
Sbjct: 293 LLRKHEGLERDLAALEDKVNTLGGDAGRLQETHPQNASQILLK-------KDELVANWEQ 345
Query: 5859 RRILYEQCMDL-------QLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHED 5701
R L F D +W+ + +A + +L + + E L+ +H++
Sbjct: 346 IRTLAADATPAWTTPTGEPRFTADFRDLTSWVTEMQALIKADELANDVAGAEALLDRHQE 405
Score = 141 bits (356), Expect = 2e-31
Identities = 88/339 (25%), Positives = 170/339 (49%)
Frame = -1
Query: 2217 QQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDY 2038
+ I +RR+ + DRY K+++ RR KL + F RD ++ E WI+EK L ++SD+
Sbjct: 13 EDIQDRRQQVLDRYRRFKELSVMRRQKLEDSYRFQCFRRDAEELEKWIQEK-LQIASDEN 71
Query: 2037 GRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLE 1858
+D +Q +KH+ + E+ ++ + + G ++ +E + I+ R+E+L
Sbjct: 72 YKDPSNLQGKLQKHQAFEAEVQANAGTIIKLDETGNLMI---SEGHFASETIRSRLEELH 128
Query: 1857 QSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLL 1678
+ W + T + RL +++ +L + E+ W+++K+ + S+ G+++ V+ L
Sbjct: 129 RLWDLLLQKTKEKGLRLLQAQKLVQYLRECEDALDWISDKEAMATSEELGQDLEHVELLQ 188
Query: 1677 KKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRL 1498
KK + FQ DL H++RV ++ LI + I ++ D++ A ++ +A+ R
Sbjct: 189 KKFEEFQTDLAAHEERVNEVNQLAAKLIQESHPEVELIVRKQDEVNAAWQRLKGLAQQRQ 248
Query: 1497 AKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFE 1318
+L + +F D SWI E+ + S+DFGRD SVQ LL K E + L A E
Sbjct: 249 GRLFGAAEVQRFNRDVDETISWIKERGALIGSDDFGRDPGSVQALLRKHEGLERDLAALE 308
Query: 1317 HEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNL 1201
+ + + +L + Q + I + ++ W+ +
Sbjct: 309 -DKVNTLGGDAGRLQETHPQNASQILLKKDELVANWEQI 346
Score = 140 bits (354), Expect = 4e-31
Identities = 88/323 (27%), Positives = 169/323 (52%)
Frame = -1
Query: 5337 STGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEA 5158
+TG +++++ A+ I DR +QV + + + + + KL ++ Q F R+ E++E
Sbjct: 3 TTGVKVLET----AEDIQDRRQQVLDRYRRFKELSVMRRQKLEDSYRFQCFRRDAEELEK 58
Query: 5157 WLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNA 4978
W+ E + Q+AS++ KD ++Q +K E++ A+ + + + E HF +
Sbjct: 59 WIQE-KLQIASDENYKDPSNLQGKLQKHQAFEAEVQANAGTIIKLDETGNLMISEGHFAS 117
Query: 4977 PVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNR 4798
I + E L + ++ L +++ +L ++ + Q R+ ED L WI +KE +A S
Sbjct: 118 ETIRSRLEELHRLWDLLLQKTKEKGLRLLQAQKLVQYLRECEDALDWISDKEAMATSEEL 177
Query: 4797 GRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNW 4618
G+DL V+ L KK + ++A H+ ++ V+ A +IQ+ H I K ++ W
Sbjct: 178 GQDLEHVELLQKKFEEFQTDLAAHEERVNEVNQLAAKLIQESHPEVELIVRKQDEVNAAW 237
Query: 4617 RILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKH 4438
+ LK A++R+ L + + ++ D +E +W+ E+ ++GS D+G+D S +ALL+KH
Sbjct: 238 QRLKGLAQQRQGRLFGAAEVQRFNRDVDETISWIKERGALIGSDDFGRDPGSVQALLRKH 297
Query: 4437 RALLSDLEAFKGTIEDLRKQASQ 4369
L DL A + + L A +
Sbjct: 298 EGLERDLAALEDKVNTLGGDAGR 320
Score = 140 bits (354), Expect = 4e-31
Identities = 95/403 (23%), Positives = 191/403 (46%), Gaps = 7/403 (1%)
Frame = -1
Query: 4134 QQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQ 3955
+ I ++ ++ D+Y+R L R++KLE++ + R+A +L +WI+ + +A+
Sbjct: 10 ETAEDIQDRRQQVLDRYRRFKELSVMRRQKLEDSYRFQCFRRDAEELEKWIQEKLQIASD 69
Query: 3954 QEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDL 3775
+ D ++ +K F+ +++AN + ++++ + S G + IR ++E+L
Sbjct: 70 ENY-KDPSNLQGKLQKHQAFEAEVQANAGTIIKLDETGNLMISEGHFASET-IRSRLEEL 127
Query: 3774 NARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQAL 3595
+ W L +L A ++ ++ R+ ++ DWI +K+ SE+ G+DL V+ L
Sbjct: 128 HRLWDLLLQKTKEKGLRLLQAQKLVQYLRECEDALDWISDKEAMATSEELGQDLEHVELL 187
Query: 3594 QRKHEGVERDLAALGDKIKSLDEKANRL-RQSHPEAAEQIYDLQRELNEQWNRLTSKANN 3418
Q+K E + DLAA +++ +++ A +L ++SHPE E I Q E+N W RL A
Sbjct: 188 QKKFEEFQTDLAAHEERVNEVNQLAAKLIQESHPEV-ELIVRKQDEVNAAWQRLKGLAQQ 246
Query: 3417 RKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDS 3238
R+ +L + + QRF D + + WI L+ S + D +ALL +H+ ++ +
Sbjct: 247 RQGRLFGAAEVQRFNRDVDETISWIKERGALIGSDDFGRDPGSVQALLRKHEGLERDLAA 306
Query: 3237 RAATFQAFDQFGNQLLNSHHYAAGDI----ENRLQGVNEARKGLEDAWVARRNILDQCLE 3070
+L +H A I + + + R DA A +
Sbjct: 307 LEDKVNTLGGDAGRLQETHPQNASQILLKKDELVANWEQIRTLAADATPAWTTPTGE--- 363
Query: 3069 LQLFYRDCEQADTWMSAREAFLAQEDPSGD--NVESLIKKHED 2947
F D +W++ +A + ++ + D E+L+ +H++
Sbjct: 364 -PRFTADFRDLTSWVTEMQALIKADELANDVAGAEALLDRHQE 405
Score = 138 bits (348), Expect = 2e-30
Identities = 91/377 (24%), Positives = 174/377 (46%), Gaps = 2/377 (0%)
Frame = -1
Query: 3831 TSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEK 3652
T V ETA I+ + + + R+R +L ++ Q F RD +E WIQEK
Sbjct: 4 TGVKVLETAEDIQDRRQQVLDRYRRFKELSVMRRQKLEDSYRFQCFRRDAEELEKWIQEK 63
Query: 3651 DDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYD 3472
E++ +D ++Q +KH+ E ++ A I LDE N + A+E I
Sbjct: 64 LQIASDENY-KDPSNLQGKLQKHQAFEAEVQANAGTIIKLDETGNLMISEGHFASETIRS 122
Query: 3471 LQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVT 3292
EL+ W+ L K + +LL + ++L + D + WI+ + +S+EL D+
Sbjct: 123 RLEELHRLWDLLLQKTKEKGLRLLQAQKLVQYLRECEDALDWISDKEAMATSEELGQDLE 182
Query: 3291 GAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLED 3112
E L ++ +E++T++ + +Q +L+ H I + VN A + L+
Sbjct: 183 HVELLQKKFEEFQTDLAAHEERVNEVNQLAAKLIQESHPEVELIVRKQDEVNAAWQRLKG 242
Query: 3111 AWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGD--NVESLIKKHEDFDK 2938
R+ L E+Q F RD ++ +W+ R A + +D D +V++L++KHE ++
Sbjct: 243 LAQQRQGRLFGAAEVQRFNRDVDETISWIKERGALIGSDDFGRDPGSVQALLRKHEGLER 302
Query: 2937 AINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQT 2758
+ E+K+ L A L + + ++ + K+D+++ W ++
Sbjct: 303 DLAALEDKVNTLGGDAGRLQETHPQNASQILLKKDELVANWEQIRTLAADATPAWTTPTG 362
Query: 2757 LQQFSRDADEIENWMTE 2707
+F+ D ++ +W+TE
Sbjct: 363 EPRFTADFRDLTSWVTE 379
Score = 101 bits (251), Expect = 3e-19
Identities = 90/401 (22%), Positives = 164/401 (40%), Gaps = 40/401 (9%)
Frame = -1
Query: 4662 APEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTD 4483
A +I+D+ Q+ D +R K + RR L+DS + + DA E + W+ EK I +
Sbjct: 12 AEDIQDRRQQVLDRYRRFKELSVMRRQKLEDSYRFQCFRRDAEELEKWIQEKLQIASDEN 71
Query: 4482 YGKDEDSAEALLKKHRALLSDLEAFKGTI------------------EDLRKQASQCK-- 4363
Y KD + + L+KH+A ++++A GTI E +R + +
Sbjct: 72 Y-KDPSNLQGKLQKHQAFEAEVQANAGTIIKLDETGNLMISEGHFASETIRSRLEELHRL 130
Query: 4362 ---------------YQEQPMGQLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRD 4228
Q Q + Q R+C AL +K S + G L + +
Sbjct: 131 WDLLLQKTKEKGLRLLQAQKLVQYLRECEDALDWISDKEAMATSEELGQDLEHVELLQKK 190
Query: 4227 WWKVEVNDRQGFVPAAYVKRIEP-----GTAQQHAQQQVNSIGGKQSEIEDKYQRLMMLG 4063
+ + + + AA+ +R+ Q + +V I KQ E+ +QRL L
Sbjct: 191 FEEFQTD------LAAHEERVNEVNQLAAKLIQESHPEVELIVRKQDEVNAAWQRLKGLA 244
Query: 4062 ETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDL 3883
+ R+ +L A + + R+ ++ WIK R A+ + G D V+ L +K + + DL
Sbjct: 245 QQRQGRLFGAAEVQRFNRDVDETISWIKERGALIGSDDFGRDPGSVQALLRKHEGLERDL 304
Query: 3882 KANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEV 3703
A E ++ + A L + A +I + ++L A W + +
Sbjct: 305 AALEDKVNTLGGDAGRLQET-HPQNASQILLKKDELVANWEQIRTLAADATPAWTTPTGE 363
Query: 3702 QRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHE 3580
RF D + W+ E + +++ D+ +AL +H+
Sbjct: 364 PRFTADFRDLTSWVTEMQALIKADELANDVAGAEALLDRHQ 404
Score = 100 bits (248), Expect = 7e-19
Identities = 59/209 (28%), Positives = 108/209 (51%)
Frame = -1
Query: 4962 KQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLI 4783
+++ + RY ++ R++KL +S++ RD E+ WI+EK Q+A N +D
Sbjct: 18 RRQQVLDRYRRFKELSVMRRQKLEDSYRFQCFRRDAEELEKWIQEKLQIASDENY-KDPS 76
Query: 4782 GVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKS 4603
+Q ++K QA AE+ + I + N MI +GHF + IR +L +L W +L
Sbjct: 77 NLQGKLQKHQAFEAEVQANAGTIIKLDETGNLMISEGHFASETIRSRLEELHRLWDLLLQ 136
Query: 4602 KAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLS 4423
K +++ L + + QYL + +A W+S+KE + S + G+D + E L KK +
Sbjct: 137 KTKEKGLRLLQAQKLVQYLRECEDALDWISDKEAMATSEELGQDLEHVELLQKKFEEFQT 196
Query: 4422 DLEAFKGTIEDLRKQASQCKYQEQPMGQL 4336
DL A + + ++ + A++ + P +L
Sbjct: 197 DLAAHEERVNEVNQLAAKLIQESHPEVEL 225
Score = 98.2 bits (243), Expect = 3e-18
Identities = 77/323 (23%), Positives = 145/323 (44%), Gaps = 32/323 (9%)
Frame = -1
Query: 7212 ILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEA-RQFQYFKRDADELNVWILEKLQT 7036
+ + A + R ++V Y+ + + ++D LE++ ++F F R+A+EL WI EK T
Sbjct: 1175 VTKEACSVSVRMKQVEELYANLLELGEKRKDMLEKSCKKFMLF-REANELQQWIHEKEGT 1233
Query: 7035 -AQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLE 6859
EE D ++ +K + F+ +++A+ + +++K + A E + +
Sbjct: 1234 LTNEEVGSDLEQVEVLQKKFDDFQKDLKANESRLRDINKVAAELESEGLMAEETPMVQAQ 1293
Query: 6858 ELHAL-----------------WXXXXXXXXXKG----IK---------LQQALKLLHFI 6769
+ L W IK L A ++ F
Sbjct: 1294 QQQELLGAAPGKDEADSKTASPWKNVRLAVQTTANFNTIKQLAEDRSHMLGSAHEVQRFH 1353
Query: 6768 RQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQAADKL 6589
R DE WI EK + ++ G DL V+ LQRK + F ++L ++N + + A++L
Sbjct: 1354 RDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAERL 1413
Query: 6588 VEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKD 6409
++ + I +K ++N AW L A RK+ L +H +QRF D + ++WI
Sbjct: 1414 IQSHPEAVEDIKEKCSELNTAWSSLVGRADQRKDKLANSHDLQRFLSDFRDLMSWINGIR 1473
Query: 6408 LALSSDDYGRDLNNVQALQRKHE 6340
+SS++ +D+ +AL +H+
Sbjct: 1474 GLVSSEELAKDVTGAEALLERHQ 1496
>gi|7441355|pir||S61217 spectrin alpha II chain - rat (fragment)
Length = 819
Score = 883 bits (2282), Expect = 0.0
Identities = 452/820 (55%), Positives = 577/820 (70%), Gaps = 37/820 (4%)
Frame = -1
Query: 4134 QQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQ 3955
++ S+ + ++E+ YQ L+ LGE RK LE++CK + L REAN+L +WI +EA
Sbjct: 3 KEAGSVSLRMKQVEELYQSLLELGEKRKGMLEKSCKKFMLFREANELQQWINEKEAALTS 62
Query: 3954 QEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQ---- 3787
+E+G DLEQVEVLQKKFDDF+ DLKANE RL+++N++A L S G V+ QQ
Sbjct: 63 EEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVY 122
Query: 3786 -------------------------------IEDLNARWRALXXXXXXXXXQLGSAHEVQ 3700
I++LN RWR+L LGSAHEVQ
Sbjct: 123 GMMPRDEADSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQ 182
Query: 3699 RFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKA 3520
RFHRD DET++WI+EK+ AL+++++G DL SVQALQRKHEG ERDLAALGDK+ SL E A
Sbjct: 183 RFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETA 242
Query: 3519 NRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIA 3340
RL QSHPE+AE + + ELN+ W L +A+ RK KL DS+D QRFLSD+RDLM WI
Sbjct: 243 QRLIQSHPESAEDLKEKCTELNQAWTSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWIN 302
Query: 3339 SMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDI 3160
+ LVSS ELA DVTGAEALLERHQE+RTEID+RA TFQAF+QFG QLL HYA+ +I
Sbjct: 303 GIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEI 362
Query: 3159 ENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDP--S 2986
+ +L +++ R LE AWV RR +LD CLELQLF+RDCEQA+ WM+AREAFL ED S
Sbjct: 363 KEKLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDS 422
Query: 2985 GDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGL 2806
D+VE+LIKKHEDFDKAIN QEEKI L+ FA+ LI +HY + +R+++LDRW L
Sbjct: 423 LDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIALDHYAKGDIANRRNEVLDRWRRL 482
Query: 2805 KEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNIQQKHQKQQAFE 2626
K +I+KR KLGESQTLQQFSRD DEIE W++EK Q A +E+Y+DPTNIQ KHQK QAFE
Sbjct: 483 KAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPTNIQSKHQKHQAFE 542
Query: 2625 AELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKE 2446
AELHAN+DRI +I GN+LIE C G E AV ARL AL DQW LV+ + EKS +LKE
Sbjct: 543 AELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKE 602
Query: 2445 ANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGE 2266
ANKQ++F +KD +FWL EVE LL SEDYGKD ASV +K LLE DI AH+DR+ +
Sbjct: 603 ANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDHASVNQPAQKAQLLEDDISAHEDRLKD 662
Query: 2265 MNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDE 2086
+N QAD L+ + F Q+ E+R I R+ +K MAT RR KLS++ +HQFFRD+DDE
Sbjct: 663 LNSQADDLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKLSESHRLHQFFRDMDDE 722
Query: 2085 ESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAE 1906
ESWIKEKKLLVSS+DYGRDL GVQNLR+KH+R++ ELA+HEP + V G++L + +
Sbjct: 723 ESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKL---SDD 779
Query: 1905 AGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQ 1786
+G+++I++R+ + W +++ L R QRL+ES +Q
Sbjct: 780 NTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQ 819
Score = 609 bits (1571), Expect = e-172
Identities = 335/810 (41%), Positives = 478/810 (58%), Gaps = 38/810 (4%)
Frame = -1
Query: 6876 IKKRLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGM 6697
+ R++++ L+ + L+++ K R+ +E+ WI EKE +T+E++G
Sbjct: 8 VSLRMKQVEELYQSLLELGEKRKGMLEKSCKKFMLFREANELQQWINEKEAALTSEEVGA 67
Query: 6696 DLEHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEG-HSEHDQIYKKRD------- 6541
DLE VE+LQ+KFDDF K+L ++ R+ +IN+ A+ L EG +E Q ++++
Sbjct: 68 DLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYGMMPR 127
Query: 6540 ----------------------------DVNDAWHRLNTLAATRKEGLFGAHQVQRFNRD 6445
++N+ W L LA R + L AH+VQRF+RD
Sbjct: 128 DEADSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRD 187
Query: 6444 ADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAE 6265
ADET WI EK+ AL++D+YG DL +VQALQRKHEG ERDLAAL K+ L + A +L +
Sbjct: 188 ADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAQRLIQ 247
Query: 6264 THPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAV 6085
+HP+ AE + +K + AW +L ++A RK L S L RFL+D+RDL+SWI ++ +
Sbjct: 248 SHPESAEDLKEKCTELNQAWTSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGL 307
Query: 6084 IGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLE 5905
+ +DELAKDV GAEALLE HQEH+ EIDARA +F GQ+L+ G SPE++EKL+
Sbjct: 308 VSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKEKLD 367
Query: 5904 KLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVE 5725
LD E++ L W +RR++ + C++LQLF+RD EQAE WM +EAFL D GDSLDSVE
Sbjct: 368 ILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVE 427
Query: 5724 HLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXX 5545
LIKKHEDF+K++ QEEKI AL FA +LI HYA D+A
Sbjct: 428 ALIKKHEDFDKAINVQEEKIAALQAFADQLIALDHYAKGDIANRRNEVLDRWRRLKAQMI 487
Query: 5544 XRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQELKA 5365
+ + L ES Q F RD DE+ +WI+EKL TA D+SY DPTNI+ K QKH FE EL A
Sbjct: 488 EKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPTNIQSKHQKHQAFEAELHA 547
Query: 5364 NENRLDDIRSTGEQIIDSGHFAA--DHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQ 5191
N +R+ + G +I+ G A D + RL + + W LV + +K KL+EA +Q
Sbjct: 548 NADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQ 607
Query: 5190 QFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLA 5011
FN I+D + WLSE+E +ASEDYGKD SV +K L+E D +AH DR+ + A
Sbjct: 608 NFNTGIKDFDFWLSEVEALLASEDYGKDHASVNQPAQKAQLLEDDISAHEDRLKDLNSQA 667
Query: 5010 QQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIR 4831
F+ + K++ + R+ ++ R+ KL ESH+ +Q FRD++DE +WI+
Sbjct: 668 DDLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKLSESHRLHQFFRDMDDEESWIK 727
Query: 4830 EKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEI 4651
EK+ + S + GRDL GVQNL KK + L AE+A H+ I+ V + EI
Sbjct: 728 EKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGQEEI 787
Query: 4650 RDKLAQLRDNWRILKSKAEKRRTDLDDSLQ 4561
+ +LAQ ++W+ LK A R L++SL+
Sbjct: 788 QQRLAQFVEHWKELKQLAAARGQRLEESLE 817
Score = 307 bits (787), Expect = 2e-81
Identities = 189/782 (24%), Positives = 381/782 (48%), Gaps = 42/782 (5%)
Frame = -1
Query: 3690 RDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRL 3511
R+ +E + WI EK+ AL SE+ G DL V+ LQ+K + ++DL A ++K +++ A L
Sbjct: 44 REANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDL 103
Query: 3510 RQSHPEAAEQIYDLQ-------------------------------------RELNEQWN 3442
+S AE++ +Q +ELNE+W
Sbjct: 104 -ESEGLMAEEVQAVQQQEVYGMMPRDEADSKTASPWKSARLMVHTVATFNSIKELNERWR 162
Query: 3441 RLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQ 3262
L A R + L +++ QRF D + +WI NQ +++ +D+ +AL +H+
Sbjct: 163 SLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHE 222
Query: 3261 EYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILD 3082
+ ++ + + + +L+ SH +A D++ + +N+A L R+ L
Sbjct: 223 GFERDLAALGDKVNSLGETAQRLIQSHPESAEDLKEKCTELNQAWTSLGKRADQRKAKLG 282
Query: 3081 QCLELQLFYRDCEQADTWMSAREAFLAQEDPSGD--NVESLIKKHEDFDKAINTQEEKIK 2908
+LQ F D +W++ ++ ++ + D E+L+++H++ I+ + +
Sbjct: 283 DSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQ 342
Query: 2907 GLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADE 2728
+ F + L+ + HY SP + K D + L++A +Q+R L LQ F RD ++
Sbjct: 343 AFEQFGQQLLAHGHYASPEIKEKLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQ 402
Query: 2727 IENWMTEKFQIAQEENYRDPTN-IQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAK 2551
ENWM + E+ D + ++ +K + F+ ++ ++IAA+ + LI
Sbjct: 403 AENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIALDH 462
Query: 2550 CGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILL 2371
G+ ++ R + D+W L EK +L E+ + F V ++E W+ E
Sbjct: 463 YAKGD--IANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTA 520
Query: 2370 QSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKL 2191
E Y KD ++++ +KH EA++ A+ DR+ + + +SL+E G + A + +L
Sbjct: 521 SDESY-KDPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARL 579
Query: 2190 --IADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGV 2017
+AD++ + + + ++ KL +A F I D + W+ E + L++S+DYG+D V
Sbjct: 580 AALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDHASV 639
Query: 2016 QNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIR 1837
+K + ++ ++++HE ++ + + ++L+ S+A Q+K++ + + + +I+
Sbjct: 640 NQPAQKAQLLEDDISAHEDRLKDLNSQADDLMTSSA---FDTSQVKEKRDTINGRFQKIK 696
Query: 1836 DLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQ 1657
+ +R +L ES F D+++EE+W+ EK+ ++ S+++G ++ GVQ L KKH +
Sbjct: 697 SMATSRRAKLSESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLE 756
Query: 1656 VDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNS 1477
+L H+ + +++ G L + I+QR Q E++ +A R +L ++
Sbjct: 757 AELAAHEPAIQGVLDTGKKLSDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESL 816
Query: 1476 AY 1471
Y
Sbjct: 817 EY 818
Score = 293 bits (751), Expect = 3e-77
Identities = 219/823 (26%), Positives = 398/823 (47%), Gaps = 9/823 (1%)
Frame = -1
Query: 3621 RDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWN 3442
++ SV ++ E + + L LG+K K + EK+ + EA E LQ+ +NE+
Sbjct: 3 KEAGSVSLRMKQVEELYQSLLELGEKRKGMLEKSCKKFMLFREANE----LQQWINEKEA 58
Query: 3441 RLTSK---ANNRKEKLLDSY--DYQRFLSDYRDLMQWIASMNQLVSSQEL-ANDVTGAEA 3280
LTS+ A+ + ++L D+Q+ L ++ I + + + S+ L A +V +
Sbjct: 59 ALTSEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQ 118
Query: 3279 LLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVA 3100
R E DS+ A+ + + L H A N ++ +NE + L+
Sbjct: 119 QEVYGMMPRDEADSKTAS-----PWKSARLMVHTVATF---NSIKELNERWRSLQQLAEE 170
Query: 3099 RRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGD--NVESLIKKHEDFDKAINT 2926
R +L E+Q F+RD ++ W+ + L ++ D +V++L +KHE F++ +
Sbjct: 171 RSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAA 230
Query: 2925 QEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQF 2746
+K+ L A+ LI+++ + + K ++ W L + Q++ KLG+S LQ+F
Sbjct: 231 LGDKVNSLGETAQRLIQSHPESAEDLKEKCTELNQAWTSLGKRADQRKAKLGDSHDLQRF 290
Query: 2745 SRDADEIENWMTE-KFQIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNN 2569
D ++ +W+ + ++ +E +D T + ++ Q E+ A + A Q G
Sbjct: 291 LSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQ 350
Query: 2568 LIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLG 2389
L+ + E + +L L+ + L K ++ L + + F + E W+
Sbjct: 351 LLAHGHYASPE--IKEKLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWMA 408
Query: 2388 EVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQI 2209
E L +ED G L SVE L+KKH + I ++++ + AD L+ D + I
Sbjct: 409 AREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIALDHYAKGDI 468
Query: 2208 AERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRD 2029
A RR + DR+ +K ++R KL ++ + QF RD+D+ E+WI EK L +SD+ +D
Sbjct: 469 ANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEK-LQTASDESYKD 527
Query: 2028 LPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSW 1849
+Q+ +KH+ + EL ++ ++ V G L+ A AG ED +K R+ L W
Sbjct: 528 PTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAG-SEDAVKARLAALADQW 586
Query: 1848 GQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKH 1669
+ + + Q+L E+ Q F +++ + W++E + +L S+++G++ A V +K
Sbjct: 587 QFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDHASVNQPAQKA 646
Query: 1668 DTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKL 1489
+ D+ H+ R+ DL ++ D L+ + +K++ D + R +I+SMA R AKL
Sbjct: 647 QLLEDDISAHEDRLKDLNSQADDLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKL 706
Query: 1488 RDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEG 1309
++ QF D ESWI EK+ V SED+GRDL+ VQ L K + +A L A E
Sbjct: 707 SESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHE-PA 765
Query: 1308 IQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEAR 1180
IQ + + +L I++R ++ W+ L + AR
Sbjct: 766 IQGVLDTGKKLSDDNTIGQEEIQQRLAQFVEHWKELKQLAAAR 808
Score = 282 bits (722), Expect = 8e-74
Identities = 184/767 (23%), Positives = 362/767 (46%), Gaps = 41/767 (5%)
Frame = -1
Query: 6570 EHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSD 6391
E + + V + + L L RK L + + R+A+E WI EK+ AL+S+
Sbjct: 4 EAGSVSLRMKQVEELYQSLLELGEKRKGMLEKSCKKFMLFREANELQQWINEKEAALTSE 63
Query: 6390 DYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETH--PDRAEAIHQKN--- 6226
+ G DL V+ LQ+K + ++DL A E ++ + K A L + +A+ Q+
Sbjct: 64 EVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYG 123
Query: 6225 ------DDTKAA-------------------------WNALKEKAQHRKDGLERSFQLHR 6139
D+K A W +L++ A+ R L + ++ R
Sbjct: 124 MMPRDEADSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQR 183
Query: 6138 FLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQ 5959
F D + WI + + D D+A +AL H+ + ++ A D N Q
Sbjct: 184 FHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAQ 243
Query: 5958 KLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNK 5779
+L++ + +++EK +L+ +SL ++R+ DLQ F D +W+N
Sbjct: 244 RLIQSHPESAEDLKEKCTELNQAWTSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWING 303
Query: 5778 QEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVA 5599
+++ +L + E L+++H++ + A+ A ++F +L+ HYA+ ++
Sbjct: 304 IRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIK 363
Query: 5598 EXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEK---LSTARDDSYL 5428
E R L + Q F RDC++ +W+ + L+T L
Sbjct: 364 EKLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSL 423
Query: 5427 DPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNE 5248
D ++ ++KH +F++ + E ++ +++ +Q+I H+A I +R +V + W
Sbjct: 424 D--SVEALIKKHEDFDKAINVQEEKIAALQAFADQLIALDHYAKGDIANRRNEVLDRWRR 481
Query: 5247 LVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGL 5068
L +K +KL E+ QQF+R+++++EAW+SE + Q AS++ KD ++Q+ +K
Sbjct: 482 LKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISE-KLQTASDESYKDPTNIQSKHQKHQA 540
Query: 5067 IESDFNAHNDRVDGIKQLAQQFQEEEHF--NAPVIVRKQENLQQRYNALRDPLEKRKRKL 4894
E++ +A+ DR+ G+ + E + + + L ++ L ++ +KL
Sbjct: 541 FEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKL 600
Query: 4893 GESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQI 4714
E+++ I+D W+ E E + S + G+D V +K Q L +I+ H+ ++
Sbjct: 601 KEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDHASVNQPAQKAQLLEDDISAHEDRL 660
Query: 4713 ESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDAN 4534
+ ++S A+D++ F ++++K + ++ +KS A RR L +S + HQ+ D +
Sbjct: 661 KDLNSQADDLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKLSESHRLHQFFRDMD 720
Query: 4533 EADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIE 4393
+ ++W+ EK+ +V S DYG+D + L KKH+ L ++L A + I+
Sbjct: 721 DEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQ 767
Score = 253 bits (646), Expect = 5e-65
Identities = 195/818 (23%), Positives = 363/818 (43%), Gaps = 73/818 (8%)
Frame = -1
Query: 5298 ADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASED 5119
A + R++QV L+ L++ K+ L ++ + R +++ W++E E + SE+
Sbjct: 5 AGSVSLRMKQVEELYQSLLELGEKRKGMLEKSCKKFMLFREANELQQWINEKEAALTSEE 64
Query: 5118 YGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPV-IVRKQE---- 4954
G DL V+ LQKK + D A+ R+ I ++A+ + E V V++QE
Sbjct: 65 VGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYGM 124
Query: 4953 -------------------------------NLQQRYNALRDPLEKRKRKLGESHQGNQL 4867
L +R+ +L+ E+R + LG +H+ +
Sbjct: 125 MPRDEADSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQRF 184
Query: 4866 FRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAAND 4687
RD ++ WI EK Q + N G DL VQ L +K + ++A ++ S+ A
Sbjct: 185 HRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAQR 244
Query: 4686 MIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEK 4507
+IQ A ++++K +L W L +A++R+ L DS ++LSD + +W++
Sbjct: 245 LIQSHPESAEDLKEKCTELNQAWTSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGI 304
Query: 4506 EPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQC------------- 4366
+V S + KD AEALL++H+ ++++A GT + + Q
Sbjct: 305 RGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKE 364
Query: 4365 -------------KYQEQPMGQLGRDCVLALYDYQ-EKSPREVSMKKGDVLTLLNASNRD 4228
K Q L L L+ E++ ++ ++ + T + D
Sbjct: 365 KLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLD 424
Query: 4227 WWKVEVNDRQGFVPAAYVKRIEPGTAQQHAQQQV-------NSIGGKQSEIEDKYQRLMM 4069
+ + + F A V+ + Q A Q + I +++E+ D+++RL
Sbjct: 425 SVEALIKKHEDFDKAINVQEEKIAALQAFADQLIALDHYAKGDIANRRNEVLDRWRRLKA 484
Query: 4068 LGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKG 3889
++ KL E+ Q R+ +++ WI S + A E D ++ +K F+
Sbjct: 485 QMIEKRSKLGESQTLQQFSRDVDEIEAWI-SEKLQTASDESYKDPTNIQSKHQKHQAFEA 543
Query: 3888 DLKANEVRLQEMNQIATALTSVGQ---TETAVRIRQQIEDLNARWRALXXXXXXXXXQLG 3718
+L AN R++ + + +L G +E AV+ R + L +W+ L +L
Sbjct: 544 ELHANADRIRGVIDMGNSLIERGACAGSEDAVKAR--LAALADQWQFLVQKSAEKSQKLK 601
Query: 3717 SAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIK 3538
A++ Q F+ + + W+ E + L SED+G+D SV +K + +E D++A D++K
Sbjct: 602 EANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDHASVNQPAQKAQLLEDDISAHEDRLK 661
Query: 3537 SLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRD 3358
L+ +A+ L S Q+ + + +N ++ ++ S A +R+ KL +S+ +F D D
Sbjct: 662 DLNSQADDLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKLSESHRLHQFFRDMDD 721
Query: 3357 LMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHH 3178
WI LVSS++ D+TG + L ++H+ E+ + Q G +L + +
Sbjct: 722 EESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNT 781
Query: 3177 YAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQ 3064
+I+ RL E K L+ AR L++ LE Q
Sbjct: 782 IGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQ 819
Score = 232 bits (592), Expect = 9e-59
Identities = 166/664 (25%), Positives = 299/664 (45%), Gaps = 39/664 (5%)
Frame = -1
Query: 6249 AEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADE 6070
A ++ + + + +L E + RK LE+S + + +L WI + +A + ++E
Sbjct: 5 AGSVSLRMKQVEELYQSLLELGEKRKGMLEKSCKKFMLFREANELQQWINEKEAALTSEE 64
Query: 6069 LAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGI--PESPEVQEK----- 5911
+ D+ E L + + + ++ A + L G+ E VQ++
Sbjct: 65 VGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYGM 124
Query: 5910 -----------------------------LEKLDHEKSSLLGLWEERRILYEQCMDLQLF 5818
+++L+ SL L EER L ++Q F
Sbjct: 125 MPRDEADSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQRF 184
Query: 5817 YRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATK 5638
+RD ++ + W+ ++ L + G L SV+ L +KHE FE+ LAA +K+N+L E A +
Sbjct: 185 HRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAQR 244
Query: 5637 LIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITE- 5461
LIQ +A+D+ E R L +S+ Q F D +++SWI
Sbjct: 245 LIQSHPESAEDLKEKCTELNQAWTSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGI 304
Query: 5460 KLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGD 5281
+ + D+ D T L++H E+ A G+Q++ GH+A+ I +
Sbjct: 305 RGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKE 364
Query: 5280 RLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLV 5101
+L ++ +L A ++ L Q F+R+ E E W++ E + +ED G L
Sbjct: 365 KLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLD 424
Query: 5100 SVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRD 4921
SV+ L KK + N +++ ++ A Q +H+ I ++ + R+ L+
Sbjct: 425 SVEALIKKHEDFDKAINVQEEKIAALQAFADQLIALDHYAKGDIANRRNEVLDRWRRLKA 484
Query: 4920 PLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIA 4741
+ +++ KLGES Q RD+++ AWI EK Q A S +D +Q+ +K QA A
Sbjct: 485 QMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTA-SDESYKDPTNIQSKHQKHQAFEA 543
Query: 4740 EIANHDSQIESVSSAANDMIQQGHFLAPE--IRDKLAQLRDNWRILKSKAEKRRTDLDDS 4567
E+ + +I V N +I++G E ++ +LA L D W+ L K+ ++ L ++
Sbjct: 544 ELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEA 603
Query: 4566 LQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDL 4387
+ + + + D W+SE E ++ S DYGKD S +K + L D+ A + ++DL
Sbjct: 604 NKQQNFNTGIKDFDFWLSEVEALLASEDYGKDHASVNQPAQKAQLLEDDISAHEDRLKDL 663
Query: 4386 RKQA 4375
QA
Sbjct: 664 NSQA 667
Score = 229 bits (584), Expect = 8e-58
Identities = 165/650 (25%), Positives = 293/650 (44%), Gaps = 5/650 (0%)
Frame = -1
Query: 7137 SQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENF-RDPSNLQAKIQKHEAFEAE 6961
++ + L A + Q F RDADE WI EK Q +N+ D +++QA +KHE FE +
Sbjct: 168 AEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERD 227
Query: 6960 VQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKL 6781
+ A + +L +T +IQ + ++E +K++ EL+ W + KL + L
Sbjct: 228 LAALGDKVNSLGETAQRLIQSHPESAEDLKEKCTELNQAWTSLGKRADQRKAKLGDSHDL 287
Query: 6780 LHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQA 6601
F+ +++ WI V+++++ D+ E L + + E+ Q
Sbjct: 288 QRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQF 347
Query: 6600 ADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWI 6421
+L+ GH +I +K D ++ L R+ L ++Q F+RD ++ W+
Sbjct: 348 GQQLLAHGHYASPEIKEKLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWM 407
Query: 6420 GEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKL-AETHPDRAE 6244
++ L+++D G L++V+AL +KHE ++ + E K+ L+ A +L A H + +
Sbjct: 408 AAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIALDHYAKGD 467
Query: 6243 AIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELA 6064
+++N + W LK + ++ L S L +F D ++ +WI + K +DE
Sbjct: 468 IANRRN-EVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISE-KLQTASDESY 525
Query: 6063 KDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPE--VQEKLEKLDHE 5890
KD ++ + HQ + E+ A AD G L+E G E V+ +L L +
Sbjct: 526 KDPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQ 585
Query: 5889 KSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKK 5710
L+ E+ ++ Q F + + W+++ EA LA+ D G SV +K
Sbjct: 586 WQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDHASVNQPAQK 645
Query: 5709 HEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNA 5530
+ E ++A E+++ L+ A L+ + V E R
Sbjct: 646 AQLLEDDISAHEDRLKDLNSQADDLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAK 705
Query: 5529 LKESYKRQTFDRDCDEMVSWITE-KLSTARDDSYLDPTNIRGKLQKHINFEQELKANENR 5353
L ES++ F RD D+ SWI E KL + +D D T ++ +KH E EL A+E
Sbjct: 706 LSESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPA 765
Query: 5352 LDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREA 5203
+ + TG+++ D + I RL Q W EL +G +L E+
Sbjct: 766 IQGVLDTGKKLSDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEES 815
Score = 211 bits (537), Expect = 2e-52
Identities = 122/351 (34%), Positives = 189/351 (53%), Gaps = 2/351 (0%)
Frame = -1
Query: 7194 DIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENFR 7015
DI RR EVL + K KR +L E++ Q F RD DE+ WI EKLQTA +E+++
Sbjct: 467 DIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYK 526
Query: 7014 DPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEH--IKKRLEELHALW 6841
DP+N+Q+K QKH+AFEAE+ A+A I + GN++I+ A +K RL L W
Sbjct: 527 DPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQW 586
Query: 6840 XXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKF 6661
K KL++A K +F + +W+ E E + +ED G D V +K
Sbjct: 587 QFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDHASVNQPAQKA 646
Query: 6660 DDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGL 6481
++ H+ R+ ++N AD L+ + Q+ +KRD +N + ++ ++A +R+ L
Sbjct: 647 QLLEDDISAHEDRLKDLNSQADDLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKL 706
Query: 6480 FGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKM 6301
+H++ +F RD D+ +WI EK L +SS+DYGRDL VQ L++KH+ E +LAA E +
Sbjct: 707 SESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAI 766
Query: 6300 LQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQ 6148
+ KL++ + E I Q+ W LK+ A R LE S +
Sbjct: 767 QGVLDTGKKLSDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLE 817
Score = 210 bits (534), Expect = 5e-52
Identities = 188/828 (22%), Positives = 358/828 (42%), Gaps = 65/828 (7%)
Frame = -1
Query: 2532 AVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYG 2353
+VS R+K + + + L++ ++ L+++ K+ +L+ W+ E E L SE+ G
Sbjct: 7 SVSLRMKQVEELYQSLLELGEKRKGMLEKSCKKFMLFREANELQQWINEKEAALTSEEVG 66
Query: 2352 KDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSL----LENDQFQGQQIAE------ 2203
DL VE L KK + D+ A++ R+ ++N+ A+ L L ++ Q Q E
Sbjct: 67 ADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYGMMP 126
Query: 2202 --------------------------RRKLIADRYDGVKKMATDRRDKLSKALNVHQFFR 2101
K + +R+ ++++A +R L A V +F R
Sbjct: 127 RDEADSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHR 186
Query: 2100 DIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELL 1921
D D+ + WI+EK +++D+YG DL VQ L+RKH + +LA+ +V+ + + L+
Sbjct: 187 DADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAQRLI 246
Query: 1920 RSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNE 1741
+S E+ + +K++ +L Q+W + R +L +S Q FL D + +W+N
Sbjct: 247 QSHPESA---EDLKEKCTELNQAWTSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWING 303
Query: 1740 KQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIK 1561
+ ++ SD +++ G + LL++H + +++ G L+ +G++ +P IK
Sbjct: 304 IRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIK 363
Query: 1560 QRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWK-CDVVESWIAEKEQQVRSEDFGRD 1384
++ D L ++E R L D+ LQ + C+ E+W+A +E + +ED G
Sbjct: 364 EKLDILDQERTDLEKAWVQRRMML-DHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDS 422
Query: 1383 LSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQN 1204
L SV+ L+ K E FD +N E E I + DQL++ +H I R V+ RW+
Sbjct: 423 LDSVEALIKKHEDFDKAINVQE-EKIAALQAFADQLIALDHYAKGDIANRRNEVLDRWRR 481
Query: 1203 LLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFEN-----AEEDLTDPVRCNS 1039
L A +R + F++ +W ++E DP
Sbjct: 482 LKAQMIEKRSKLGE--------SQTLQQFSRDVDEIEAWISEKLQTASDESYKDPT---- 529
Query: 1038 LEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRI--KSFNVGPNPYTWFTMDALEDTWR 865
I++ H F+ L + + R + D+ + + G + AL D W+
Sbjct: 530 --NIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQ 587
Query: 864 NLQRIIKEREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEM-MEAGGTLEEQL 688
L + E+ Q+L +++Q N ++ F WL+ + E G +
Sbjct: 588 FLVQKSAEKSQKLKEANKQQNFNTGIK--------DFDFWLSEVEALLASEDYGKDHASV 639
Query: 687 DAVERKAK----EIKANKGQLRQIEEKGAMLERNLILDNRYTEHSTVGIAQAWDQLDQLA 520
+ +KA+ +I A++ +L+ + + L + D + I + ++ +A
Sbjct: 640 NQPAQKAQLLEDDISAHEDRLKDLNSQADDLMTSSAFDTSQVKEKRDTINGRFQKIKSMA 699
Query: 519 ------MRMQHNLEQQIQARN--QSGVSEEALREFSMMFKHFDKEKTG----RLDHQQFK 376
+ H L Q + + +S + E+ L S + + ++ TG R H++ +
Sbjct: 700 TSRRAKLSESHRLHQFFRDMDDEESWIKEKKLLVSS---EDYGRDLTGVQNLRKKHKRLE 756
Query: 375 SCLRALGYDLPMVDEGQPEPEFQRILD----IVDPNRDGYVTLQEYMA 244
+ L A EP Q +LD + D N G +Q+ +A
Sbjct: 757 AELAA------------HEPAIQGVLDTGKKLSDDNTIGQEEIQQRLA 792
Score = 153 bits (387), Expect = 5e-35
Identities = 108/438 (24%), Positives = 194/438 (43%), Gaps = 3/438 (0%)
Frame = -1
Query: 7128 KRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENFRDP-SNLQAKIQKHEAFEAEVQA 6952
+R L+ + Q F RD ++ W+ + E+ D +++A I+KHE F+ +
Sbjct: 383 RRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINV 442
Query: 6951 HAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKLLHF 6772
+ IA L + +I +H+A I R E+ W K KL ++ L F
Sbjct: 443 QEEKIAALQAFADQLIALDHYAKGDIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQF 502
Query: 6771 IRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQAADK 6592
R DEI WI EK +++ D +++ +K F EL + RI + +
Sbjct: 503 SRDVDEIEAWISEK-LQTASDESYKDPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNS 561
Query: 6591 LVEEGH--SEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIG 6418
L+E G D + + + D W L +A + + L A++ Q FN + W+
Sbjct: 562 LIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLS 621
Query: 6417 EKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAI 6238
E + L+S+DYG+D +V +K + E D++A E ++ L +A L + +
Sbjct: 622 EVEALLASEDYGKDHASVNQPAQKAQLLEDDISAHEDRLKDLNSQADDLMTSSAFDTSQV 681
Query: 6237 HQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKD 6058
+K D + +K A R+ L S +LH+F D D SWI + K ++ +++ +D
Sbjct: 682 KEKRDTINGRFQKIKSMATSRRAKLSESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRD 741
Query: 6057 VAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSL 5878
+ G + L + H+ + E+ A + G+KL + E+Q++L + L
Sbjct: 742 LTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGQEEIQQRLAQFVEHWKEL 801
Query: 5877 LGLWEERRILYEQCMDLQ 5824
L R E+ ++ Q
Sbjct: 802 KQLAAARGQRLEESLEYQ 819
>gi|12847774|dbj|BAB27703.1| unnamed protein product [Mus musculus]
Length = 654
Score = 802 bits (2072), Expect = 0.0
Identities = 387/636 (60%), Positives = 494/636 (76%), Gaps = 6/636 (0%)
Frame = -1
Query: 1899 VGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGS 1720
+G+++I++R+ + W +++ L R QRL+ES +Q F+ +VEEEEAW+NEK ++ S
Sbjct: 18 IGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVAS 77
Query: 1719 DNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLR 1540
+++G+ +A +QGLLKKH+ F+ D +HK RV D+ G LI NHH +I + L
Sbjct: 78 EDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGLN 137
Query: 1539 ARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILL 1360
++ ++E A R AKL +NSA+LQF WK DVVESWI EKE ++++D+GRDLSSVQ LL
Sbjct: 138 GKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLL 197
Query: 1359 TKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEAR 1180
TKQE FDAGL AF+ EGI IT LKDQL++++H QS AIE RH ++++RW LLA+S R
Sbjct: 198 TKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHASLMKRWTQLLANSATR 257
Query: 1179 RXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGE 1000
+ ++E+L+L FAKKAS FNSWFENAEEDLTDPVRCNSLEEI+ALR+AH
Sbjct: 258 KKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDA 317
Query: 999 FQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAR 820
F+ SLSSA+ DF QL +LDR+IKSF V NPYTWFTM+ALE+TWRNLQ+IIKERE EL +
Sbjct: 318 FRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFTMEALEETWRNLQKIIKERELELQK 377
Query: 819 EHQRQEENDKLRREFAKLANAFHAWLTNTRQE------MMEAGGTLEEQLDAVERKAKEI 658
E +RQEENDKLR+EFA+ ANAFH W+ TR M+E GTLE QL+A +RK +EI
Sbjct: 378 EQRRQEENDKLRQEFAQHANAFHQWIQETRTYLLDGSCMVEESGTLESQLEATKRKHQEI 437
Query: 657 KANKGQLRQIEEKGAMLERNLILDNRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQAR 478
+A + QL++IE+ GA +E LILDN+YTEHSTVG+AQ WDQLDQL MRMQHNLEQQIQAR
Sbjct: 438 RAMRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQQWDQLDQLGMRMQHNLEQQIQAR 497
Query: 477 NQSGVSEEALREFSMMFKHFDKEKTGRLDHQQFKSCLRALGYDLPMVDEGQPEPEFQRIL 298
N +GV+EEAL+EFSMMFKHFDK+K+GRL+HQ+FKSCLR+LGYDLPMV+EG+P+PEF+ IL
Sbjct: 498 NTTGVTEEALKEFSMMFKHFDKDKSGRLNHQEFKSCLRSLGYDLPMVEEGEPDPEFEAIL 557
Query: 297 DIVDPNRDGYVTLQEYMAFMISKETENIQSSEEIEMAFRALSKEFRPYVTAEELYANLTP 118
D VDPNRDG+V+LQEYMAFMIS+ETEN++SSEEIE AFRALS E +PYVT EELY NLT
Sbjct: 558 DTVDPNRDGHVSLQEYMAFMISRETENVKSSEEIESAFRALSSEGKPYVTKEELYQNLTR 617
Query: 117 EQAEFCIRRMKPYMDAISGRSIQGGLDYEQFVHALF 10
EQA++C+ MKPY+D GR + DY +F +LF
Sbjct: 618 EQADYCVSHMKPYVDG-KGRELPTAFDYVEFTRSLF 652
Score = 132 bits (331), Expect = 2e-28
Identities = 88/327 (26%), Positives = 151/327 (45%), Gaps = 10/327 (3%)
Frame = -1
Query: 2598 IAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMA 2419
I ++ G L ++ G E + RL + W L + + RL+E+ + + F+A
Sbjct: 2 IQGVLDTGKKLSDDNTIGQEE--IQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVA 59
Query: 2418 AVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLL 2239
V++ E W+ E L+ SEDYG LA+++ LLKKH E D H+DRV ++ L+
Sbjct: 60 NVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLI 119
Query: 2238 ENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKL 2059
+ + + I+ + K + + ++K A R+ KL + QF D ESWI EK+
Sbjct: 120 KKNNHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKEN 179
Query: 2058 LVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQ--VSLVKLKGEELLRSAAEAGVGEDQ 1885
+ +DDYGRDL VQ L K D L + + + ++ LK + L A +
Sbjct: 180 SLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLL----AAKHIQSKA 235
Query: 1884 IKKRMEDLEQSWGQIRDLTGNRHQRLDESEA--------FQAFLGDVEEEEAWMNEKQQI 1729
I+ R L + W Q+ + R ++L E+++ F F +W ++
Sbjct: 236 IEARHASLMKRWTQLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFENAEED 295
Query: 1728 LGSDNFGENMAGVQGLLKKHDTFQVDL 1648
L ++ ++ L + HD F+ L
Sbjct: 296 LTDPVRCNSLEEIKALREAHDAFRSSL 322
Score = 126 bits (316), Expect = 9e-27
Identities = 94/340 (27%), Positives = 153/340 (44%), Gaps = 10/340 (2%)
Frame = -1
Query: 5352 LDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNI 5173
+ + TG+++ D + I RL Q W EL +G +L E+ QQF N+
Sbjct: 2 IQGVLDTGKKLSDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANV 61
Query: 5172 EDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEE 4993
E+ EAW++E VASEDYG L ++Q L KK E+DF H DRV+ + Q ++
Sbjct: 62 EEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKK 121
Query: 4992 EHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVA 4813
+ + I K + L + + L +RK KL E+ Q + +WI EKE
Sbjct: 122 NNHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSL 181
Query: 4812 GSTNRGRDLIGVQNLIKKQQALIAEI-ANHDSQIESVSSAANDMIQQGHFLAPEIRDKLA 4636
+ + GRDL VQ L+ KQ+ A + A I ++++ + ++ H + I + A
Sbjct: 182 KTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHA 241
Query: 4635 QLRDNWRILKSKAEKRRTDLDDSLQAH------QYLSDANEADA---WMSEKEPIVGSTD 4483
L W L + + R+ L ++ Q+H +L+ A +A A W E +
Sbjct: 242 SLMKRWTQLLANSATRKKKLLEA-QSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPV 300
Query: 4482 YGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCK 4363
+ +AL + H A S L + + L + Q K
Sbjct: 301 RCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIK 340
Score = 124 bits (312), Expect = 3e-26
Identities = 113/448 (25%), Positives = 196/448 (43%), Gaps = 32/448 (7%)
Frame = -1
Query: 5538 GNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDP-TNIRGKLQKHINFEQELKAN 5362
G L+ES + Q F + +E +WI EK++ + Y D I+G L+KH FE + +
Sbjct: 45 GQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVH 104
Query: 5361 ENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFN 5182
++R++D+ + G+ +I + ++I +++ +N ++L A ++ AKL E QFN
Sbjct: 105 KDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFN 164
Query: 5181 RNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNA-HNDRVDGIKQLAQQ 5005
+ VE+W+ E E + ++DYG+DL SVQ L K ++ A + + I L Q
Sbjct: 165 WKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQ 224
Query: 5004 FQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDEL------ 4843
+H + I + +L +R+ L RK+KL E+ FR +ED
Sbjct: 225 LLAAKHIQSKAIEARHASLMKRWTQLLANSATRKKKLLEAQSH---FRKVEDLFLTFAKK 281
Query: 4842 -----AWIREKEQVAGSTNRGRDLIGVQNL----------IKKQQALIAEIANHDSQIES 4708
+W E+ R L ++ L + QA ++A D QI+S
Sbjct: 282 ASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKS 341
Query: 4707 VSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKS---------KAEKRRTDLDDSLQAH 4555
A+N P + L + WR L+ + E+RR + +D L+
Sbjct: 342 FRVASN----------PYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLR-Q 390
Query: 4554 QYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQA 4375
++ AN W+ E + Y D ++++ L S LEA K +++R
Sbjct: 391 EFAQHANAFHQWIQE------TRTYLLD---GSCMVEESGTLESQLEATKRKHQEIRAMR 441
Query: 4374 SQCKYQEQPMGQLGRDCVLALYDYQEKS 4291
SQ K E +G + ++ Y E S
Sbjct: 442 SQLKKIED-LGAAMEEALILDNKYTEHS 468
Score = 124 bits (310), Expect = 4e-26
Identities = 104/444 (23%), Positives = 186/444 (41%), Gaps = 22/444 (4%)
Frame = -1
Query: 6921 TGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYW 6742
TG + N E I++RL + W +G +L+++L+ F+ +E W
Sbjct: 8 TGKKLSDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAW 67
Query: 6741 IREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHD 6562
I EK T V +ED G L ++ L +K + F + H+ R+N++ L+++ + +
Sbjct: 68 INEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEE 127
Query: 6561 QIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYG 6382
I K +N L AA RK L +FN AD +WIGEK+ +L +DDYG
Sbjct: 128 NISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYG 187
Query: 6381 RDLNNVQALQRKHEGTERDLAALEGK-MLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAW 6205
RDL++VQ L K E + L A + + + + +L +++AI ++ W
Sbjct: 188 RDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHASLMKRW 247
Query: 6204 NALKEKAQHRKDGLERSFQLHRFLADY--------RDLISWIGDMKAVIGADELAKDVAG 6049
L + RK L + R + D SW + + + +
Sbjct: 248 TQLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEE 307
Query: 6048 AEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHE------- 5890
+AL E+H + + + FNQ A +++ + +P +E L+
Sbjct: 308 IKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFTMEALEETWRNLQKI 367
Query: 5889 -KSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLAN-----TDLGDSLDSV 5728
K L L +E+R E Q F + W+ + +L + + G +
Sbjct: 368 IKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRTYLLDGSCMVEESGTLESQL 427
Query: 5727 EHLIKKHEDFEKSLAAQEEKINAL 5656
E +KH++ +++ +Q +KI L
Sbjct: 428 EATKRKHQEI-RAMRSQLKKIEDL 450
Score = 107 bits (268), Expect = 3e-21
Identities = 78/312 (25%), Positives = 136/312 (43%), Gaps = 10/312 (3%)
Frame = -1
Query: 7197 DDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENF 7018
++I QR + + H+ K + + RLEE+ ++Q F + +E WI EK+ E++
Sbjct: 21 EEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDY 80
Query: 7017 RDP-SNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALW 6841
D + +Q ++KHEAFE + H + ++ G +I+ N+ E+I +++ L+
Sbjct: 81 GDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKV 140
Query: 6840 XXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKF 6661
+ KL + L F + D + WI EKE + +D G DL V+ L K
Sbjct: 141 SDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQ 200
Query: 6660 DDFLKELGNHQYR-INEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEG 6484
+ F L Q I I D+L+ H + I + + W +L +ATRK+
Sbjct: 201 ETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHASLMKRWTQLLANSATRKKK 260
Query: 6483 LFGAHQVQR--------FNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTER 6328
L A R F + A +W + L+ L ++AL+ H+
Sbjct: 261 LLEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRS 320
Query: 6327 DLAALEGKMLQL 6292
L++ + QL
Sbjct: 321 SLSSAQADFNQL 332
Score = 102 bits (255), Expect = 1e-19
Identities = 113/509 (22%), Positives = 213/509 (41%), Gaps = 48/509 (9%)
Frame = -1
Query: 4125 NSIGGKQ-----SEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVA 3961
N+IG ++ ++ + ++ L L R ++LEE+ + Q + + WI + +
Sbjct: 16 NTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLV 75
Query: 3960 AQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIE 3781
A ++ G L ++ L KK + F+ D ++ R+ ++ L I +++
Sbjct: 76 ASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEE-NISSKMK 134
Query: 3780 DLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQ 3601
LN + L +L +F+ D WI EK+++L ++D+GRDL SVQ
Sbjct: 135 GLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQ 194
Query: 3600 ALQRKHEGVERDLAALGDK-IKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKA 3424
L K E + L A + I ++ ++L + ++ I L ++W +L + +
Sbjct: 195 TLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHASLMKRWTQLLANS 254
Query: 3423 NNRKEKLLDSYDYQRFLSDY--------RDLMQWIASMNQLVSSQELANDVTGAEALLER 3268
RK+KLL++ + R + D W + + ++ N + +AL E
Sbjct: 255 ATRKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEIKALREA 314
Query: 3267 HQEYRTEIDSRAATFQAFDQFGNQL----LNSHHYAAGDIENRLQGVNEARKGLEDAWVA 3100
H +R+ + S A F + Q+ + S+ Y +E LE+ W
Sbjct: 315 HDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFTME-----------ALEETWRN 363
Query: 3099 RRNIL-DQCLELQLFYRDCEQAD--------------TWMSAREAFL----AQEDPSG-- 2983
+ I+ ++ LELQ R E+ D W+ +L + SG
Sbjct: 364 LQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRTYLLDGSCMVEESGTL 423
Query: 2982 -DNVESLIKKHEDFDKAINTQEEKIKGL-KLFAESLIKNNHYDSPAVT------RKRDQI 2827
+E+ +KH++ +A+ +Q +KI+ L E+LI +N Y + + DQ+
Sbjct: 424 ESQLEATKRKHQEI-RAMRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQQWDQLDQL 482
Query: 2826 LDRWNGLKEALIQKRFKLG-ESQTLQQFS 2743
R E IQ R G + L++FS
Sbjct: 483 GMRMQHNLEQQIQARNTTGVTEEALKEFS 511
Score = 100 bits (248), Expect = 7e-19
Identities = 94/448 (20%), Positives = 184/448 (40%), Gaps = 33/448 (7%)
Frame = -1
Query: 3543 IKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDY 3364
I+ + + +L + E+I + E W L A R ++L +S +YQ+F+++
Sbjct: 2 IQGVLDTGKKLSDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANV 61
Query: 3363 RDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNS 3184
+ WI LV+S++ + + + LL++H+ + T+ G L+
Sbjct: 62 EEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKK 121
Query: 3183 HHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFL 3004
+++ +I ++++G+N LE A R+ LD+ F + ++W+ +E L
Sbjct: 122 NNHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSL 181
Query: 3003 AQEDPSGD--NVESLIKKHEDFDKAINT-QEEKIKGLKLFAESLIKNNHYDSPAVTRKRD 2833
+D D +V++L+ K E FD + Q+E I + + L+ H S A+ +
Sbjct: 182 KTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHA 241
Query: 2832 QILDRWNGLKEALIQKRFKLGESQT--------LQQFSRDADEIENWMTEKFQIAQEENY 2677
++ RW L ++ KL E+Q+ F++ A +W EE+
Sbjct: 242 SLMKRWTQLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFEN-----AEEDL 296
Query: 2676 RDPT------NIQQKHQKQQAFEAEL---HANSDRIAAIIQAGNNLIENAKCGGGEAAVS 2524
DP I+ + AF + L A+ +++A + + I++ +
Sbjct: 297 TDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAEL----DRQIKSFRVASNPYTWF 352
Query: 2523 ARLKALNDQWDLLVKTTTEKSYRL-KEANKQ-------KSFMAAVKDLEFWLGEVEILL- 2371
++AL + W L K E+ L KE +Q + F W+ E L
Sbjct: 353 T-MEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRTYLL 411
Query: 2370 ----QSEDYGKDLASVENLLKKHSLLEA 2299
E+ G + +E +KH + A
Sbjct: 412 DGSCMVEESGTLESQLEATKRKHQEIRA 439
Score = 98.2 bits (243), Expect = 3e-18
Identities = 131/601 (21%), Positives = 240/601 (39%), Gaps = 42/601 (6%)
Frame = -1
Query: 6621 INEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDA 6442
I + KL ++ ++I ++ + W L LAA R + L + + Q+F +
Sbjct: 2 IQGVLDTGKKLSDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANV 61
Query: 6441 DETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAET 6262
+E AWI EK ++S+DYG L +Q L +KHE E D + ++ + L +
Sbjct: 62 EEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKK 121
Query: 6261 HPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVI 6082
+ E I K + L++ A RK L+ + +F + SWIG+ + +
Sbjct: 122 NNHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSL 181
Query: 6081 GADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEK 5902
D+ +D++ + LL + DA +F Q A ++ + + +Q K +
Sbjct: 182 KTDDYGRDLSSVQTLLTKQE----TFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIE 237
Query: 5901 LDHEKSSLLGLW---------EERRIL-----YEQCMDLQL-FYRDTEQAETWMNKQEAF 5767
H +SL+ W ++++L + + DL L F + +W E
Sbjct: 238 ARH--ASLMKRWTQLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFENAEED 295
Query: 5766 LANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQ-------HYAAD 5608
L + +SL+ ++ L + H+ F SL++ + N L E ++ + + +
Sbjct: 296 LTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFTME 355
Query: 5607 DVAEXXXXXXXXXXXXXXXXXXRGNALKESYK-RQTFDRDCDEMVSWITEKLSTARDDSY 5431
+ E +E+ K RQ F + + WI E + D S
Sbjct: 356 ALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRTYLLDGSC 415
Query: 5430 L--DPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQ-----IIDSGHFAADHIG---- 5284
+ + + +L+ QE++A ++L I G I+D+ + +G
Sbjct: 416 MVEESGTLESQLEATKRKHQEIRAMRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQQ 475
Query: 5283 -DRLRQV-----NNLWNELVDATNKKGAKLREAGNE--QQFNRNIEDVEAWLSELEGQVA 5128
D+L Q+ +NL + + A N G EA E F +D L+ E +
Sbjct: 476 WDQLDQLGMRMQHNL-EQQIQARNTTGV-TEEALKEFSMMFKHFDKDKSGRLNHQEFKSC 533
Query: 5127 SEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENL 4948
G DL V+ G + +F A D VD + QE + A +I R+ EN+
Sbjct: 534 LRSLGYDLPMVEE-----GEPDPEFEAILDTVDPNRDGHVSLQE---YMAFMISRETENV 585
Query: 4947 Q 4945
+
Sbjct: 586 K 586
Score = 95.1 bits (235), Expect = 2e-17
Identities = 109/506 (21%), Positives = 200/506 (38%), Gaps = 45/506 (8%)
Frame = -1
Query: 3828 SVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKD 3649
++GQ E R+ Q +E W+ L +L + E Q+F +V+E WI EK
Sbjct: 17 TIGQEEIQQRLAQFVE----HWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKM 72
Query: 3648 DALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDL 3469
+ SED+G L ++Q L +KHE E D D++ + L + + E I
Sbjct: 73 TLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSK 132
Query: 3468 QRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTG 3289
+ LN + + L A RK KL ++ + +F + WI + + + D++
Sbjct: 133 MKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSS 192
Query: 3288 AEALLERHQEYRTEIDSRAATFQAFDQFG--------NQLLNSHHYAAGDIENR------ 3151
+ LL + + + A QAF Q G +QLL + H + IE R
Sbjct: 193 VQTLLTKQETF-------DAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHASLMK 245
Query: 3150 -----LQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDP- 2989
L +K L +A R + D L F + ++W E L DP
Sbjct: 246 RWTQLLANSATRKKKLLEAQSHFRKVEDLFL---TFAKKASAFNSWFENAEEDLT--DPV 300
Query: 2988 ---SGDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDR 2818
S + +++L + H+ F ++++ + L + +P + + +
Sbjct: 301 RCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFTMEALEET 360
Query: 2817 WNGLKEALIQKRFKLGESQ--------TLQQFSRDADEIENWMTEKFQIAQE-------- 2686
W L++ + ++ +L + Q Q+F++ A+ W+ E +
Sbjct: 361 WRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRTYLLDGSCMVEES 420
Query: 2685 ---ENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQA---GNNLIENAKCGGGEAAVS 2524
E+ + T ++KHQ+ +A ++L D AA+ +A N E++ G
Sbjct: 421 GTLESQLEAT--KRKHQEIRAMRSQLKKIEDLGAAMEEALILDNKYTEHSTVG------- 471
Query: 2523 ARLKALNDQWDLLVKTTTEKSYRLKE 2446
L QWD L + + L++
Sbjct: 472 -----LAQQWDQLDQLGMRMQHNLEQ 492
Score = 94.7 bits (234), Expect = 3e-17
Identities = 101/512 (19%), Positives = 206/512 (39%), Gaps = 25/512 (4%)
Frame = -1
Query: 5988 SFNQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRD 5809
S G+KL + E+Q++L + L L R E+ ++ Q F +
Sbjct: 1 SIQGVLDTGKKLSDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVAN 60
Query: 5808 TEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQ 5629
E+ E W+N++ +A+ D GD+L +++ L+KKHE FE ++++N + LI+
Sbjct: 61 VEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIK 120
Query: 5628 GQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLST 5449
++ ++++ R L E+ F+ D + SWI EK ++
Sbjct: 121 KNNHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENS 180
Query: 5448 ARDDSY-LDPTNIRGKLQKHINFEQELKA-NENRLDDIRSTGEQIIDSGHFAADHIGDRL 5275
+ D Y D ++++ L K F+ L+A + + +I + +Q++ + H + I R
Sbjct: 181 LKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARH 240
Query: 5274 RQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDV-----------EAWLSELEGQVA 5128
+ W +L+ + + KL EA Q R +ED+ +W E +
Sbjct: 241 ASLMKRWTQLLANSATRKKKLLEA---QSHFRKVEDLFLTFAKKASAFNSWFENAEEDLT 297
Query: 5127 SEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENL 4948
L ++ L++ S ++ + + +L +Q + + P E L
Sbjct: 298 DPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFTMEAL 357
Query: 4947 QQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELA--------WIREKEQ--VAGS--T 4804
++ + L+ +++R+ +L + + + + E A WI+E + GS
Sbjct: 358 EETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRTYLLDGSCMV 417
Query: 4803 NRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRD 4624
L K++ I + + +IE + +A + + + LAQ
Sbjct: 418 EESGTLESQLEATKRKHQEIRAMRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQ--- 474
Query: 4623 NWRILKSKAEKRRTDLDDSLQAHQYLSDANEA 4528
W L + + +L+ +QA EA
Sbjct: 475 QWDQLDQLGMRMQHNLEQQIQARNTTGVTEEA 506
Score = 82.8 bits (203), Expect = 1e-13
Identities = 81/418 (19%), Positives = 160/418 (37%), Gaps = 11/418 (2%)
Frame = -1
Query: 1629 VADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKC 1450
+ +++ G L + I+QR Q E++ +A R +L ++ Y QF+
Sbjct: 2 IQGVLDTGKKLSDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANV 61
Query: 1449 DVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVS 1270
+ E+WI EK V SED+G L+++Q LL K EAF+ + T +D +
Sbjct: 62 EEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKK 121
Query: 1269 SEHQQSPAIEKRH--TNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTF 1096
+ H + K + + A +A+ +L F KA
Sbjct: 122 NNHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDE-----------NSAFLQFNWKADVV 170
Query: 1095 NSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSS-AEEDFRQLQDLDRRIKSFNV 919
SW E L L ++ L F L + +E + L ++ +
Sbjct: 171 ESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKH 230
Query: 918 GPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLANAFHAWLT 739
+ +L W L R+++L + + L FAK A+AF++W
Sbjct: 231 IQSKAIEARHASLMKRWTQLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFE 290
Query: 738 NTRQEM--------MEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERNLILDN 583
N +++ +E L E DA +A+ QL +++ + ++ + N
Sbjct: 291 NAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQ---IKSFRVASN 347
Query: 582 RYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMMFKHFDKE 409
YT + + + W L ++ + L+++ + + ++ + + + F + +E
Sbjct: 348 PYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQE 405
>gi|836669|gb|AAB60364.1| alpha II spectrin [Homo sapiens]
Length = 719
Score = 774 bits (1999), Expect = 0.0
Identities = 398/719 (55%), Positives = 506/719 (70%), Gaps = 60/719 (8%)
Frame = -1
Query: 4803 NRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRD 4624
NRG+DLIGVQNL+KK QAL AEIA H+ +I++V+ N M+++GHF A +++ KL +L
Sbjct: 1 NRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLHELNQ 60
Query: 4623 NWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLK 4444
W LK+KA +RR DL+DSLQA QY +DANEA++WM EKEPIVGSTDYGKDEDSAEALLK
Sbjct: 61 KWEALKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLK 120
Query: 4443 KHRALLSDLEAFKGTIEDLRKQASQCKYQEQPMG-QLGRDCVLALYDYQEKSPREVSMKK 4267
KH AL+SDL A+ +I+ LR+QA C+ Q P + G++ VLALYDYQEKSPREV+MKK
Sbjct: 121 KHEALMSDLSAYGSSIQALREQAQSCRQQVAPTDDETGKELVLALYDYQEKSPREVTMKK 180
Query: 4266 GDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIEPGTA--------------------- 4150
GD+LTLLN++N+DWWKVEVNDRQGFVPAAYVK+++P +
Sbjct: 181 GDILTLLNSTNKDWWKVEVNDRQGFVPAAYVKKLDPAQSASRENLLEEQGSIALRQEQID 240
Query: 4149 -QQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSR 3973
Q ++ S+ + ++E+ Y L+ LGE RK LE++CK + L REAN+L +WI +
Sbjct: 241 NQTRITKEAGSVSLRMKQVEELYHSLLELGEKRKGMLEKSCKKFMLFREANELQQWINEK 300
Query: 3972 EAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIR 3793
EA +E+G DLEQVEVLQKKFDDF+ DLKANE RL+++N++A L S G V+
Sbjct: 301 EAALTSEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAV 360
Query: 3792 QQ-----------------------------------IEDLNARWRALXXXXXXXXXQLG 3718
QQ I++LN RWR+L LG
Sbjct: 361 QQQEVYGMMPRDETDSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLG 420
Query: 3717 SAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIK 3538
SAHEVQRFHRD DET++WI+EK+ AL+++++G DL SVQALQRKHEG ERDLAALGDK+
Sbjct: 421 SAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVN 480
Query: 3537 SLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRD 3358
SL E A RL QSHPE+AE + + ELN+ W+ L +A+ RK KL DS+D QRFLSD+RD
Sbjct: 481 SLGETAERLIQSHPESAEDLQEKCTELNQAWSSLGKRADQRKAKLGDSHDLQRFLSDFRD 540
Query: 3357 LMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHH 3178
LM WI + LVSS ELA DVTGAEALLERHQE+RTEID+RA TFQAF+QFG QLL H
Sbjct: 541 LMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGH 600
Query: 3177 YAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQ 2998
YA+ +I+ +L +++ R LE AWV RR +LDQCLELQLF+RDCEQA+ WM+AREAFL
Sbjct: 601 YASPEIKQKLDILDQERADLEKAWVQRRMMLDQCLELQLFHRDCEQAENWMAAREAFLNT 660
Query: 2997 ED--PSGDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQI 2827
ED S D+VE+LIKKHEDFDKAIN QEEKI L+ FA+ LI HY ++ +R+++
Sbjct: 661 EDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAAGHYAKGDISSRRNEV 719
Score = 382 bits (981), Expect = e-104
Identities = 204/462 (44%), Positives = 291/462 (62%), Gaps = 36/462 (7%)
Frame = -1
Query: 6876 IKKRLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGM 6697
+ R++++ L+ + L+++ K R+ +E+ WI EKE +T+E++G
Sbjct: 252 VSLRMKQVEELYHSLLELGEKRKGMLEKSCKKFMLFREANELQQWINEKEAALTSEEVGA 311
Query: 6696 DLEHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEG-HSEHDQIYKKRD------- 6541
DLE VE+LQ+KFDDF K+L ++ R+ +IN+ A+ L EG +E Q ++++
Sbjct: 312 DLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYGMMPR 371
Query: 6540 ----------------------------DVNDAWHRLNTLAATRKEGLFGAHQVQRFNRD 6445
++N+ W L LA R + L AH+VQRF+RD
Sbjct: 372 DETDSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRD 431
Query: 6444 ADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAE 6265
ADET WI EK+ AL++D+YG DL +VQALQRKHEG ERDLAAL K+ L + A +L +
Sbjct: 432 ADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAERLIQ 491
Query: 6264 THPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAV 6085
+HP+ AE + +K + AW++L ++A RK L S L RFL+D+RDL+SWI ++ +
Sbjct: 492 SHPESAEDLQEKCTELNQAWSSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGL 551
Query: 6084 IGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLE 5905
+ +DELAKDV GAEALLE HQEH+ EIDARA +F GQ+L+ G SPE+++KL+
Sbjct: 552 VSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKQKLD 611
Query: 5904 KLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVE 5725
LD E++ L W +RR++ +QC++LQLF+RD EQAE WM +EAFL D GDSLDSVE
Sbjct: 612 ILDQERADLEKAWVQRRMMLDQCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVE 671
Query: 5724 HLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVA 5599
LIKKHEDF+K++ QEEKI AL FA +LI HYA D++
Sbjct: 672 ALIKKHEDFDKAINVQEEKIAALQAFADQLIAAGHYAKGDIS 713
Score = 246 bits (629), Expect = 5e-63
Identities = 180/731 (24%), Positives = 338/731 (45%), Gaps = 38/731 (5%)
Frame = -1
Query: 3300 DVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKG 3121
D+ G + LL++HQ + EI +A Q GN ++ H+AA D++ +L +N+ +
Sbjct: 5 DLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLHELNQKWEA 64
Query: 3120 LEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQED--PSGDNVESLIKKHED 2947
L+ RR L+ L+ Q ++ D +A++WM +E + D D+ E+L+KKHE
Sbjct: 65 LKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKHEA 124
Query: 2946 FDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGE 2767
++ I+ L+ A+S + + T K + +L ++ +++ + K G+
Sbjct: 125 LMSDLSAYGSSIQALREQAQSC-RQQVAPTDDETGK-ELVLALYDYQEKSPREVTMKKGD 182
Query: 2766 SQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAI 2587
TL + ++W K ++ + + +++ Q A L IA
Sbjct: 183 ILTLLNSTN-----KDWW--KVEVNDRQGFVPAAYVKKLDPAQSASRENLLEEQGSIALR 235
Query: 2586 IQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKD 2407
+ +N K G +VS R+K + + + L++ ++ L+++ K+ +
Sbjct: 236 QEQIDNQTRITKEAG---SVSLRMKQVEELYHSLLELGEKRKGMLEKSCKKFMLFREANE 292
Query: 2406 LEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSL----L 2239
L+ W+ E E L SE+ G DL VE L KK + D+ A++ R+ ++N+ A+ L L
Sbjct: 293 LQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGL 352
Query: 2238 ENDQFQGQQIAE--------------------------------RRKLIADRYDGVKKMA 2155
++ Q Q E K + +R+ ++++A
Sbjct: 353 MAEEVQAVQQQEVYGMMPRDETDSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLA 412
Query: 2154 TDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTEL 1975
+R L A V +F RD D+ + WI+EK +++D+YG DL VQ L+RKH + +L
Sbjct: 413 EERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDL 472
Query: 1974 ASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESE 1795
A+ +V+ + E L++S E+ + ++++ +L Q+W + R +L +S
Sbjct: 473 AALGDKVNSLGETAERLIQSHPESA---EDLQEKCTELNQAWSSLGKRADQRKAKLGDSH 529
Query: 1794 AFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLI 1615
Q FL D + +W+N + ++ SD +++ G + LL++H + +++
Sbjct: 530 DLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFE 589
Query: 1614 NKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVES 1435
G L+ +G++ +P IKQ+ D L ++E R L F C+ E+
Sbjct: 590 QFGQQLLAHGHYASPEIKQKLDILDQERADLEKAWVQRRMMLDQCLELQLFHRDCEQAEN 649
Query: 1434 WIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQ 1255
W+A +E + +ED G L SV+ L+ K E FD +N + E I + DQL+++ H
Sbjct: 650 WMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINV-QEEKIAALQAFADQLIAAGHYA 708
Query: 1254 SPAIEKRHTNV 1222
I R V
Sbjct: 709 KGDISSRRNEV 719
Score = 231 bits (588), Expect = 3e-58
Identities = 174/729 (23%), Positives = 332/729 (44%), Gaps = 42/729 (5%)
Frame = -1
Query: 6702 GMDLEHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAW 6523
G DL V+ L +K E+ H+ RI + Q + +VEEGH + + K ++N W
Sbjct: 3 GKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLHELNQKW 62
Query: 6522 HRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKH 6343
L A+ R++ L + Q Q++ DA+E +W+ EK+ + S DYG+D ++ +AL +KH
Sbjct: 63 EALKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKH 122
Query: 6342 EGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGL 6163
E DL+A + L ++A + A + + A +EK+ R+ +
Sbjct: 123 EALMSDLSAYGSSIQALREQAQSCRQ---QVAPTDDETGKELVLALYDYQEKSP-REVTM 178
Query: 6162 ERSFQLHRFLADYRDLISW---IGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARA 5992
++ L + +D W + D + + A + K A E+ E +G I R
Sbjct: 179 KKGDILTLLNSTNKDW--WKVEVNDRQGFVPAAYVKKLDPAQSASRENLLEEQGSIALRQ 236
Query: 5991 DSF-NQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFY 5815
+ NQT E+ V ++++++ SLL L E+R+ + E+ + +
Sbjct: 237 EQIDNQTRIT---------KEAGSVSLRMKQVEELYHSLLELGEKRKGMLEKSCKKFMLF 287
Query: 5814 RDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKL 5635
R+ + + W+N++EA L + ++G L+ VE L KK +DF+K L A E ++ +++ A L
Sbjct: 288 REANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDL 347
Query: 5634 IQGQHYAADDV----------------AEXXXXXXXXXXXXXXXXXXRGNALKESYKR-- 5509
+ + A++V + N++KE +R
Sbjct: 348 -ESEGLMAEEVQAVQQQEVYGMMPRDETDSKTASPWKSARLMVHTVATFNSIKELNERWR 406
Query: 5508 -------------------QTFDRDCDEMVSWITEKLSTARDDSY-LDPTNIRGKLQKHI 5389
Q F RD DE WI EK D+Y D +++ +KH
Sbjct: 407 SLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHE 466
Query: 5388 NFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLR 5209
FE++L A ++++ + T E++I S +A+ + ++ ++N W+ L +++ AKL
Sbjct: 467 GFERDLAALGDKVNSLGETAERLIQSHPESAEDLQEKCTELNQAWSSLGKRADQRKAKLG 526
Query: 5208 EAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVD 5029
++ + Q+F + D+ +W++ + G V+S++ KD+ + L ++ ++ +A
Sbjct: 527 DSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQ 586
Query: 5028 GIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIED 4849
+Q QQ H+ +P I +K + L Q L +R+ L + + RD E
Sbjct: 587 AFEQFGQQLLAHGHYASPEIKQKLDILDQERADLEKAWVQRRMMLDQCLELQLFHRDCEQ 646
Query: 4848 ELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGH 4669
W+ +E + ++G L V+ LIKK + I + +I ++ + A+ +I GH
Sbjct: 647 AENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAAGH 706
Query: 4668 FLAPEIRDK 4642
+ +I +
Sbjct: 707 YAKGDISSR 715
Score = 217 bits (552), Expect = 4e-54
Identities = 178/774 (22%), Positives = 333/774 (42%), Gaps = 15/774 (1%)
Frame = -1
Query: 5427 DPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNE 5248
D ++ L+KH + E+ +E R+ + G +++ GHFAA+ + +L ++N W
Sbjct: 5 DLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLHELNQKWEA 64
Query: 5247 LVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGL 5068
L +++ L ++ QQ+ + + E+W+ E E V S DYGKD S + L KK
Sbjct: 65 LKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKHEA 124
Query: 5067 IESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRK--- 4897
+ SD +A+ + +++ AQ +++ V E ++ AL D EK R+
Sbjct: 125 LMSDLSAYGSSIQALREQAQSCRQQ------VAPTDDETGKELVLALYDYQEKSPREVTM 178
Query: 4896 -------LGESHQGNQLFRDIEDELAWIR----EKEQVAGSTNRGRDLIGVQNLIKKQQA 4750
L S + ++ D ++ +K A S +R +NL+++Q
Sbjct: 179 KKGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVKKLDPAQSASR-------ENLLEEQ-- 229
Query: 4749 LIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDD 4570
IA QI++ + + A + ++ Q+ + + L EKR+ L+
Sbjct: 230 --GSIALRQEQIDNQTRITKE--------AGSVSLRMKQVEELYHSLLELGEKRKGMLEK 279
Query: 4569 SLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIED 4390
S + +ANE W++EKE + S + G D + E L KK DL+A + ++D
Sbjct: 280 SCKKFMLFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANESRLKD 339
Query: 4389 LRKQASQCKYQEQPMGQLGRDCVLALYDYQEKSPREV-SMKKGDVLTLLNASNRDWWKVE 4213
+ K A + + L + Q +EV M D AS WK
Sbjct: 340 INKVAEDLESEG-----------LMAEEVQAVQQQEVYGMMPRDETDSKTASP---WK-- 383
Query: 4212 VNDRQGFVPAAYVKRIEPGTAQQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEA 4033
H NSI E+ ++++ L L E R + L A
Sbjct: 384 -----------------SARLMVHTVATFNSI----KELNERWRSLQQLAEERSQLLGSA 422
Query: 4032 CKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEM 3853
+ + R+A++ EWI+ + G DL V+ LQ+K + F+ DL A ++ +
Sbjct: 423 HEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSL 482
Query: 3852 NQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDET 3673
+ A L E+A ++++ +LN W +L +LG +H++QRF D +
Sbjct: 483 GETAERLIQ-SHPESAEDLQEKCTELNQAWSSLGKRADQRKAKLGDSHDLQRFLSDFRDL 541
Query: 3672 RDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPE 3493
WI + S++ +D+ +AL +H+ ++ A ++ ++ +L
Sbjct: 542 MSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHY 601
Query: 3492 AAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQ 3313
A+ +I L+++ L R+ L + Q F D W+A+ ++++
Sbjct: 602 ASPEIKQKLDILDQERADLEKAWVQRRMMLDQCLELQLFHRDCEQAENWMAAREAFLNTE 661
Query: 3312 ELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENR 3151
+ + + EAL+++H+++ I+ + A F +QL+ + HYA GDI +R
Sbjct: 662 DKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAAGHYAKGDISSR 715
Score = 216 bits (550), Expect = 7e-54
Identities = 162/688 (23%), Positives = 297/688 (42%), Gaps = 39/688 (5%)
Frame = -1
Query: 6384 GRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAW 6205
G+DL VQ L +KH+ + ++A E ++ + ++ + + E AE + K + W
Sbjct: 3 GKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLHELNQKW 62
Query: 6204 NALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESH 6025
ALK KA R+ LE S Q ++ AD + SW+ + + ++G+ + KD AEALL+ H
Sbjct: 63 EALKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKH 122
Query: 6024 QEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKL--EKLDHEKSSLLGLWEERRI 5851
+ ++ A S Q + P E ++L D+++ S + ++
Sbjct: 123 EALMSDLSAYGSSIQALREQAQSCRQQVAPTDDETGKELVLALYDYQEKSPREVTMKKGD 182
Query: 5850 LYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEE 5671
+ + E + A++ D S S E+L+++ + S+A ++E
Sbjct: 183 ILTLLNSTNKDWWKVEVNDRQGFVPAAYVKKLDPAQSA-SRENLLEE----QGSIALRQE 237
Query: 5670 KINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRD 5491
+I+ + A V+ R L++S K+ R+
Sbjct: 238 QIDNQTRITKE--------AGSVSLRMKQVEELYHSLLELGEKRKGMLEKSCKKFMLFRE 289
Query: 5490 CDEMVSWITEKLSTARDDSY-LDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIID 5314
+E+ WI EK + + D + +K +F+++LKANE+RL DI E +
Sbjct: 290 ANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLES 349
Query: 5313 SGHFAADHIG------------------------------------DRLRQVNNLWNELV 5242
G A + + ++++N W L
Sbjct: 350 EGLMAEEVQAVQQQEVYGMMPRDETDSKTASPWKSARLMVHTVATFNSIKELNERWRSLQ 409
Query: 5241 DATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIE 5062
++ L A Q+F+R+ ++ + W+ E + +++YG DL SVQ LQ+K E
Sbjct: 410 QLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFE 469
Query: 5061 SDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESH 4882
D A D+V+ + + A++ + +A + K L Q +++L ++RK KLG+SH
Sbjct: 470 RDLAALGDKVNSLGETAERLIQSHPESAEDLQEKCTELNQAWSSLGKRADQRKAKLGDSH 529
Query: 4881 QGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVS 4702
+ D D ++WI + S +D+ G + L+++ Q EI ++
Sbjct: 530 DLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFE 589
Query: 4701 SAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADA 4522
++ GH+ +PEI+ KL L L+ +RR LD L+ + D +A+
Sbjct: 590 QFGQQLLAHGHYASPEIKQKLDILDQERADLEKAWVQRRMMLDQCLELQLFHRDCEQAEN 649
Query: 4521 WMSEKEPIVGSTDYGKDEDSAEALLKKH 4438
WM+ +E + + D G DS EAL+KKH
Sbjct: 650 WMAAREAFLNTEDKGDSLDSVEALIKKH 677
Score = 200 bits (508), Expect = 5e-49
Identities = 152/610 (24%), Positives = 266/610 (42%), Gaps = 45/610 (7%)
Frame = -1
Query: 6063 KDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHEKS 5884
KD+ G + LL+ HQ + EI G +VE G + +V+ KL +L+ +
Sbjct: 4 KDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLHELNQKWE 63
Query: 5883 SLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHE 5704
+L +RR E + Q ++ D +AE+WM ++E + +TD G DS E L+KKHE
Sbjct: 64 ALKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKHE 123
Query: 5703 DFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXX--XXXXXRGNA 5530
L+A I AL E A Q D+ + +G+
Sbjct: 124 ALMSDLSAYGSSIQALREQAQSCRQQVAPTDDETGKELVLALYDYQEKSPREVTMKKGDI 183
Query: 5529 L-------KESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQEL 5371
L K+ +K + DR +++ +KL A+ S + +G I QE
Sbjct: 184 LTLLNSTNKDWWKVEVNDRQGFVPAAYV-KKLDPAQSASRENLLEEQGS----IALRQEQ 238
Query: 5370 KANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQ 5191
N+ R+ A + R++QV L++ L++ K+ L ++ +
Sbjct: 239 IDNQTRITK--------------EAGSVSLRMKQVEELYHSLLELGEKRKGMLEKSCKKF 284
Query: 5190 QFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLA 5011
R +++ W++E E + SE+ G DL V+ LQKK + D A+ R+ I ++A
Sbjct: 285 MLFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVA 344
Query: 5010 QQFQEEEHFNAPV-IVRKQE-----------------------------------NLQQR 4939
+ + E V V++QE L +R
Sbjct: 345 EDLESEGLMAEEVQAVQQQEVYGMMPRDETDSKTASPWKSARLMVHTVATFNSIKELNER 404
Query: 4938 YNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKK 4759
+ +L+ E+R + LG +H+ + RD ++ WI EK Q + N G DL VQ L +K
Sbjct: 405 WRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRK 464
Query: 4758 QQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTD 4579
+ ++A ++ S+ A +IQ A ++++K +L W L +A++R+
Sbjct: 465 HEGFERDLAALGDKVNSLGETAERLIQSHPESAEDLQEKCTELNQAWSSLGKRADQRKAK 524
Query: 4578 LDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGT 4399
L DS ++LSD + +W++ +V S + KD AEALL++H+ ++++A GT
Sbjct: 525 LGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGT 584
Query: 4398 IEDLRKQASQ 4369
+ + Q
Sbjct: 585 FQAFEQFGQQ 594
Score = 200 bits (508), Expect = 5e-49
Identities = 162/719 (22%), Positives = 306/719 (42%), Gaps = 41/719 (5%)
Frame = -1
Query: 7017 RDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWX 6838
+D +Q ++KH+A +AE+ H I + + GNAM++ HFA+E +K +L EL+ W
Sbjct: 4 KDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLHELNQKWE 63
Query: 6837 XXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFD 6658
+ L+ +L+ + +E W+REKE V + D G D + E L +K +
Sbjct: 64 ALKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKHE 123
Query: 6657 DFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEG-- 6484
+ +L + I + + A ++ D+ K+ + + T K+G
Sbjct: 124 ALMSDLSAYGSSIQALREQAQSCRQQVAPTDDETGKELVLALYDYQEKSPREVTMKKGDI 183
Query: 6483 --LFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALE 6310
L + + + ++ ++ Y + L+ Q+ R++ E+ AL
Sbjct: 184 LTLLNSTNKDWWKVEVNDRQGFVPAA--------YVKKLDPAQSASRENLLEEQGSIALR 235
Query: 6309 GKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLA 6130
+ + + K A ++ + + +++L E + RK LE+S +
Sbjct: 236 QEQIDNQTRITK-------EAGSVSLRMKQVEELYHSLLELGEKRKGMLEKSCKKFMLFR 288
Query: 6129 DYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEI---DARADSFNQTA---- 5971
+ +L WI + +A + ++E+ D+ E L + + + ++ ++R N+ A
Sbjct: 289 EANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLE 348
Query: 5970 SAGQKLVEMGIPESPEVQ-----------------------------EKLEKLDHEKSSL 5878
S G E+ + EV +++L+ SL
Sbjct: 349 SEGLMAEEVQAVQQQEVYGMMPRDETDSKTASPWKSARLMVHTVATFNSIKELNERWRSL 408
Query: 5877 LGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDF 5698
L EER L ++Q F+RD ++ + W+ ++ L + G L SV+ L +KHE F
Sbjct: 409 QQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGF 468
Query: 5697 EKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKES 5518
E+ LAA +K+N+L E A +LIQ +A+D+ E R L +S
Sbjct: 469 ERDLAALGDKVNSLGETAERLIQSHPESAEDLQEKCTELNQAWSSLGKRADQRKAKLGDS 528
Query: 5517 YKRQTFDRDCDEMVSWITE-KLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDI 5341
+ Q F D +++SWI + + D+ D T L++H E+ A
Sbjct: 529 HDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAF 588
Query: 5340 RSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVE 5161
G+Q++ GH+A+ I +L ++ +L A ++ L + Q F+R+ E E
Sbjct: 589 EQFGQQLLAHGHYASPEIKQKLDILDQERADLEKAWVQRRMMLDQCLELQLFHRDCEQAE 648
Query: 5160 AWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHF 4984
W++ E + +ED G L SV+ L KK + N +++ ++ A Q H+
Sbjct: 649 NWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAAGHY 707
Score = 188 bits (478), Expect = 1e-45
Identities = 151/685 (22%), Positives = 298/685 (43%), Gaps = 40/685 (5%)
Frame = -1
Query: 7200 ADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEEN 7021
A+D+ + E+ + K + +R LE++ Q Q + DA+E W+ EK +
Sbjct: 48 AEDVKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGSTD 107
Query: 7020 F-RDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHAL 6844
+ +D + +A ++KHEA +++ A+ +I L + + Q + K L + AL
Sbjct: 108 YGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPTDDETGKEL--VLAL 165
Query: 6843 WXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRK 6664
+ +K L LL+ + D + +++ +V A + L+ + R
Sbjct: 166 YDYQEKSPREVTMKKGDILTLLNSTNK-DWWKVEVNDRQGFVPAAYV-KKLDPAQSASR- 222
Query: 6663 FDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEG 6484
++ L+E G+ R +I+ E G + + V + +H L L RK
Sbjct: 223 -ENLLEEQGSIALRQEQIDNQTRITKEAG-----SVSLRMKQVEELYHSLLELGEKRKGM 276
Query: 6483 LFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGK 6304
L + + R+A+E WI EK+ AL+S++ G DL V+ LQ+K + ++DL A E +
Sbjct: 277 LEKSCKKFMLFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANESR 336
Query: 6303 MLQLEKEAHKLAETH--PDRAEAIHQKN---------DDTKAA----------------- 6208
+ + K A L + +A+ Q+ D+K A
Sbjct: 337 LKDINKVAEDLESEGLMAEEVQAVQQQEVYGMMPRDETDSKTASPWKSARLMVHTVATFN 396
Query: 6207 --------WNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVA 6052
W +L++ A+ R L + ++ RF D + WI + + D D+A
Sbjct: 397 SIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLA 456
Query: 6051 GAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLG 5872
+AL H+ + ++ A D N ++L++ + ++QEK +L+ SSL
Sbjct: 457 SVQALQRKHEGFERDLAALGDKVNSLGETAERLIQSHPESAEDLQEKCTELNQAWSSLGK 516
Query: 5871 LWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEK 5692
++R+ DLQ F D +W+N +++ +L + E L+++H++
Sbjct: 517 RADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRT 576
Query: 5691 SLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYK 5512
+ A+ A ++F +L+ HYA+ ++ + R L + +
Sbjct: 577 EIDARAGTFQAFEQFGQQLLAHGHYASPEIKQKLDILDQERADLEKAWVQRRMMLDQCLE 636
Query: 5511 RQTFDRDCDEMVSWITEK---LSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDI 5341
Q F RDC++ +W+ + L+T LD ++ ++KH +F++ + E ++ +
Sbjct: 637 LQLFHRDCEQAENWMAAREAFLNTEDKGDSLD--SVEALIKKHEDFDKAINVQEEKIAAL 694
Query: 5340 RSTGEQIIDSGHFAADHIGDRLRQV 5266
++ +Q+I +GH+A I R +V
Sbjct: 695 QAFADQLIAAGHYAKGDISSRRNEV 719
Score = 186 bits (472), Expect = 7e-45
Identities = 161/709 (22%), Positives = 296/709 (41%), Gaps = 34/709 (4%)
Frame = -1
Query: 2976 VESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEA 2797
V++L+KKH+ I E +IK + ++++ H+ + V K ++ +W LK
Sbjct: 9 VQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLHELNQKWEALKAK 68
Query: 2796 LIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENY-RDPTNIQQKHQKQQAFEAE 2620
Q+R L +S QQ+ DA+E E+WM EK I +Y +D + + +K +A ++
Sbjct: 69 ASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSD 128
Query: 2619 LHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEAN 2440
L A I A+ + + + E L + Q + T +K L N
Sbjct: 129 LSAYGSSIQALREQAQSCRQQVAPTDDETGKELVLALYDYQEKSPREVTMKKGDILTLLN 188
Query: 2439 KQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMN 2260
++W EV A V+ L S +++ Q +
Sbjct: 189 STNK--------DWWKVEVN----DRQGFVPAAYVKKLDPAQSASRENLLEEQGSIALRQ 236
Query: 2259 EQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEES 2080
EQ D+ + G ++ R K + + Y + ++ R+ L K+ FR+ ++ +
Sbjct: 237 EQIDNQTRITKEAGS-VSLRMKQVEELYHSLLELGEKRKGMLEKSCKKFMLFREANELQQ 295
Query: 2079 WIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEEL----LRSA 1912
WI EK+ ++S++ G DL V+ L++K +L ++E ++ + E+L L +
Sbjct: 296 WINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAE 355
Query: 1911 AEAGVGEDQIKKRM-----------------------------EDLEQSWGQIRDLTGNR 1819
V + ++ M ++L + W ++ L R
Sbjct: 356 EVQAVQQQEVYGMMPRDETDSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEER 415
Query: 1818 HQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELH 1639
Q L + Q F D +E + W+ EK Q L +DN+G ++A VQ L +KH+ F+ DL
Sbjct: 416 SQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAAL 475
Query: 1638 KQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFM 1459
+V L + LI + A ++++C +L + A+ R AKL D+ +F+
Sbjct: 476 GDKVNSLGETAERLIQSHPESAEDLQEKCTELNQAWSSLGKRADQRKAKLGDSHDLQRFL 535
Query: 1458 WKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQ 1279
+ SWI V S++ +D++ + LL + + ++A Q + Q
Sbjct: 536 SDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDA-RAGTFQAFEQFGQQ 594
Query: 1278 LVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKAST 1099
L++ H SP I+++ + Q +L RR EL L F +
Sbjct: 595 LLAHGHYASPEIKQKLDILDQERADLEKAWVQRRMMLDQCL-------ELQL-FHRDCEQ 646
Query: 1098 FNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQ 952
+W E L + +SL+ + AL H +F ++++ EE LQ
Sbjct: 647 AENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQ 695
Score = 159 bits (403), Expect = 7e-37
Identities = 141/659 (21%), Positives = 270/659 (40%), Gaps = 42/659 (6%)
Frame = -1
Query: 2676 RDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQ 2497
+D +Q +K QA +AE+ + RI A+ Q GN ++E + V A+L LN +
Sbjct: 4 KDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAED--VKAKLHELNQK 61
Query: 2496 WDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKK 2317
W+ L +++ L+++ + + + A + E W+ E E ++ S DYGKD S E LLKK
Sbjct: 62 WEALKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKK 121
Query: 2316 HSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDK 2137
H L +D+ A+ + + EQA S Q ++L+ YD +K + K
Sbjct: 122 HEALMSDLSAYGSSIQALREQAQSC--RQQVAPTDDETGKELVLALYDYQEKSPREVTMK 179
Query: 2136 ------LSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTEL 1975
L + N + +++D + ++ Y + L Q+ R++ L
Sbjct: 180 KGDILTLLNSTNKDWWKVEVNDRQGFVPAA--------YVKKLDPAQSASREN------L 225
Query: 1974 ASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESE 1795
+ ++L + + + R EAG + RM+ +E+ + + +L R L++S
Sbjct: 226 LEEQGSIALRQEQIDNQTRITKEAG----SVSLRMKQVEELYHSLLELGEKRKGMLEKSC 281
Query: 1794 AFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLI 1615
+ E + W+NEK+ L S+ G ++ V+ L KK D FQ DL+ ++ R+ D+
Sbjct: 282 KKFMLFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDIN 341
Query: 1614 NKGDTLIHNG------------------------------------NHHAPHIKQRCDQL 1543
+ L G H +L
Sbjct: 342 KVAEDLESEGLMAEEVQAVQQQEVYGMMPRDETDSKTASPWKSARLMVHTVATFNSIKEL 401
Query: 1542 RARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQIL 1363
R ++ +AE R L +F D + WI EK Q + ++++G DL+SVQ L
Sbjct: 402 NERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQAL 461
Query: 1362 LTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEA 1183
K E F+ L A + + + E ++L+ S + + ++++ T + Q W +L ++
Sbjct: 462 QRKHEGFERDLAAL-GDKVNSLGETAERLIQSHPESAEDLQEKCTELNQAWSSLGKRADQ 520
Query: 1182 RRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHG 1003
R+ + + SW ++ + AL + H
Sbjct: 521 RKAKLGDSHDLQRFLSDF--------RDLMSWINGIRGLVSSDELAKDVTGAEALLERHQ 572
Query: 1002 EFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQEL 826
E + + + F+ + +++ + +P +D L+ +L++ +R L
Sbjct: 573 EHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKQKLDILDQERADLEKAWVQRRMML 631
Score = 127 bits (318), Expect = 5e-27
Identities = 132/648 (20%), Positives = 267/648 (40%), Gaps = 38/648 (5%)
Frame = -1
Query: 2355 GKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRY 2176
GKDL V+NLLKKH L+A+I H+ R+ + ++ ++++E F + + + + ++
Sbjct: 3 GKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLHELNQKW 62
Query: 2175 DGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKH 1996
+ +K A+ RR L +L Q+F D ++ ESW++EK+ +V S DYG+D + L +KH
Sbjct: 63 EALKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKH 122
Query: 1995 RRIDTELASHEPQVSLVKLKGEELLRSAA--EAGVGEDQIKKRMEDLEQSWGQIRDLTGN 1822
+ ++L+++ + ++ + + + A + G++ + + E+S R++T
Sbjct: 123 EALMSDLSAYGSSIQALREQAQSCRQQVAPTDDETGKELVLALYDYQEKS---PREVTMK 179
Query: 1821 RHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGE----NMAGVQGLLKKHDTFQV 1654
+ L + VE +N++Q + + + A + LL++ Q
Sbjct: 180 KGDILTLLNSTNKDWWKVE-----VNDRQGFVPAAYVKKLDPAQSASRENLLEE----QG 230
Query: 1653 DLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSA 1474
+ L ++++ T I A + R Q+ + + E R L +
Sbjct: 231 SIALRQEQI-----DNQTRI---TKEAGSVSLRMKQVEELYHSLLELGEKRKGMLEKSCK 282
Query: 1473 YLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEH--EGIQR 1300
+ + ++ WI EKE + SE+ G DL V++L K + F L A E + I +
Sbjct: 283 KFMLFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINK 342
Query: 1299 ITE-------LKDQLVSSEHQQSPAI---EKRHTNVIQRWQN--LLAHSEARRXXXXXXX 1156
+ E + +++ + + Q+ + ++ + W++ L+ H+ A
Sbjct: 343 VAEDLESEGLMAEEVQAVQQQEVYGMMPRDETDSKTASPWKSARLMVHTVATFNSIKELN 402
Query: 1155 XXXXQIEEL-------------YLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALR 1015
+++L F + A W E + L + L ++AL+
Sbjct: 403 ERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQ 462
Query: 1014 DAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKERE 835
H F+R L++ + L + R+ + L W +L + +R+
Sbjct: 463 RKHEGFERDLAALGDKVNSLGETAERLIQSHPESAEDLQEKCTELNQAWSSLGKRADQRK 522
Query: 834 QELAREHQRQEENDKLRREFAKLANAFHAWLTNTR-----QEMMEAGGTLEEQLDAVERK 670
+L H Q + +F L +W+ R E+ + E L+ +
Sbjct: 523 AKLGDSHDLQ----RFLSDFRDLM----SWINGIRGLVSSDELAKDVTGAEALLERHQEH 574
Query: 669 AKEIKANKGQLRQIEEKGAMLERNLILDNRYTEHSTVGIAQAWDQLDQ 526
EI A G + E+ G L + +++ I Q D LDQ
Sbjct: 575 RTEIDARAGTFQAFEQFGQQL-------LAHGHYASPEIKQKLDILDQ 615
Score = 89.0 bits (219), Expect = 2e-15
Identities = 90/381 (23%), Positives = 166/381 (42%), Gaps = 10/381 (2%)
Frame = -1
Query: 1716 NFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRA 1537
N G+++ GVQ LLKKH Q ++ H+ R+ + KG+ ++ G+ A +K + +L
Sbjct: 1 NRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLHELNQ 60
Query: 1536 RLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLT 1357
+ +++ A R L D+ Q+ + ESW+ EKE V S D+G+D S + LL
Sbjct: 61 KWEALKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLK 120
Query: 1356 KQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARR 1177
K EA + L+A+ I L++Q S Q +P ++ ++ LA + +
Sbjct: 121 KHEALMSDLSAYG----SSIQALREQAQSCRQQVAPTDDETGKELV------LALYDYQE 170
Query: 1176 XXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEI----RALRDA 1009
I L ST W++ D V ++++ A R+
Sbjct: 171 KSPREVTMKKGDILTLL------NSTNKDWWKVEVNDRQGFVPAAYVKKLDPAQSASREN 224
Query: 1008 HGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQE 829
E Q S++ +E + + S ++ M +E+ + +L + ++R+
Sbjct: 225 LLEEQGSIALRQEQIDNQTRITKEAGSVSL--------RMKQVEELYHSLLELGEKRKGM 276
Query: 828 LAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEMM--EAGGTLEEQLDAVERK----A 667
L ++ + L RE AN W+ + E G L EQ++ +++K
Sbjct: 277 L----EKSCKKFMLFRE----ANELQQWINEKEAALTSEEVGADL-EQVEVLQKKFDDFQ 327
Query: 666 KEIKANKGQLRQIEEKGAMLE 604
K++KAN+ +L+ I + LE
Sbjct: 328 KDLKANESRLKDINKVAEDLE 348
>gi|31209523|ref|XP_313728.1| ENSANGP00000017034 [Anopheles gambiae]
gi|21297077|gb|EAA09222.1| ENSANGP00000017034 [Anopheles gambiae str.
PEST]
Length = 4091
Score = 766 bits (1977), Expect = 0.0
Identities = 575/2301 (24%), Positives = 1047/2301 (44%), Gaps = 59/2301 (2%)
Frame = -1
Query: 7128 KRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENFRDP-SNLQAKIQKHEAFEAEVQA 6952
K +L++ + Q F R+AD+++ + ++ + +++A +++H FE + A
Sbjct: 1308 KEKKLQQCIELQIFNREADKIDATTKSHEAYLEYDDLGNSLDDVEAIMKRHIDFENSLGA 1367
Query: 6951 HAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKLLHF 6772
K + N + + +I++NH+ + +I R ++ A + LQ + F
Sbjct: 1368 QDKILKNFSEGADRLIRNNHYNATYIDDRRGQVLARRERVKELAQKRRNALQASKDFQKF 1427
Query: 6771 IRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQAADK 6592
D++ W+ +K T + +++ DL ++ +K F +EL ++ ++ +N+ +
Sbjct: 1428 SSDVDDLNRWLADK-TKIASDESYKDLSNLPRKLQKHKAFERELRANEGQLRMVNKEGES 1486
Query: 6591 LVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEK 6412
L++ ++ ++ + +N W L + + L A + NR +++ + E
Sbjct: 1487 LIKT-NNRAGEVSETLAAINQNWKDLVATSLDKGRRLEQAALQREHNRYIEDSKSKFEEL 1545
Query: 6411 DLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQ 6232
D AL S G DL + + L KH+ E D+A E K+ +L ++A A I
Sbjct: 1546 DHALQSKQVGNDLRSCKELMNKHQVLENDIALWEQKVAELVTTGEEMAHEGHFDANNIQN 1605
Query: 6231 KNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVA 6052
+ +A + LK A+ R+D L+ S + H+F+ + + WI + ++ + +++
Sbjct: 1606 ETKKLQAQFAGLKTPARQRRDALDESLRFHKFVFELDTELQWINEHLPAAKSEVIGQNLH 1665
Query: 6051 GAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLG 5872
A++L + H++ + EI+ N+T ++ + L+ PE +V+E L+ + L
Sbjct: 1666 QAQSLSKKHKKLEAEIEGHQPMINKTLTSAENLINQNHPERAKVKELCNSLEKAWADLQE 1725
Query: 5871 LWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEK 5692
ER E + Q + D + ETW+ ++ L ++D G DS L+ KH+ E
Sbjct: 1726 QSAERSRKLELSLKAQQYLSDAGEIETWLGERNNVLRSSDYGRDRDSATKLLTKHKVIEL 1785
Query: 5691 SLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYK 5512
L ++ + A+ +I +H + +A R L ES
Sbjct: 1786 ELDTYSGIVSEMGHTASAMIAAKHPDSKVIAAKQQLIEKMLKSLQRLAGQRQLRLMESLY 1845
Query: 5511 RQTFDRDCDEMVSWITEKLSTARDDSY-LDPTNIRGKLQKHINFEQELKANENRLDDIRS 5335
R + + E+ WI E+ + Y D ++ K + + ++ R + +
Sbjct: 1846 RHEYFVESAELEQWIKEQEQAVNSEDYGHDYEHLLILQNKFDDLKHRIEVGAERFNQCEN 1905
Query: 5334 TGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAW 5155
+++I I R ++N W L++ + + KL AG +F+R+ +
Sbjct: 1906 FAKKLIGGDSPYVSEIEKRQELLSNAWQHLLEQLDAREKKLHAAGEIHRFHRDAAEALFR 1965
Query: 5154 LSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDR----VDGIKQLAQQFQEEEH 4987
+ + ++SE GKDL S L +K E++ + VD +L ++ +
Sbjct: 1966 IQDKNAALSSE-LGKDLNSALALARKHEAFENELVPLEAQLQVLVDDSLRLQTKYPGD-- 2022
Query: 4986 FNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGS 4807
NA I +QEN+ Q +N L++ R +L S + D ++W +
Sbjct: 2023 -NAKAIAAEQENVIQYWNVLKEKSALRNDQLHASCDLQHFLTQVRDLMSWATNLRAALQA 2081
Query: 4806 TNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLR 4627
D G L + A+ EI + ++ ++ M+Q GH+ A E+ +K + L
Sbjct: 2082 EEHVSDAAGATALKIQHDAIYGEIEAREQTFRELNELSDSMVQTGHYAATEVEEKCSALL 2141
Query: 4626 DNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALL 4447
D L S K++ L+ + ++ DA D S +E + S+D+G+ + + +
Sbjct: 2142 DERAKLHSAYNKKKILLEQKIDLFCFMRDAKVIDNISSGQEATLSSSDFGQTVEVVQDQV 2201
Query: 4446 KKHRALLSDLEA-----------------------------FKGTIEDLRKQASQCKYQE 4354
K+H A ++ + +E +K C +
Sbjct: 2202 KRHEAFEKLIQTQDEKVAILQEHGRKLVEQNHYDSENIRRRLREIVERRQKVKDLCALRR 2261
Query: 4353 QPMG------QLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGF 4192
Q + Q RDC A EK + + D + ASN + ++ Q F
Sbjct: 2262 QKLANALLYAQFIRDCAEAGAWINEKQKK----LEADAHSYAGASNMEDKVKKLKKLQAF 2317
Query: 4191 VPAAYVKRIEPGTAQQHAQQQVNSIGGKQSEIEDKYQRLM-----MLGE--TRKRKLEEA 4033
+ ++ + EI+D+ +LM +L E +R R L+EA
Sbjct: 2318 DAEVNANEGRIREVRDKGEKLIAKKHECAGEIQDELVKLMQSWNVLLNELASRSRGLKEA 2377
Query: 4032 CKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEM 3853
+ + + L WI+ +E + E G DLE L++K DD D++ ++ R++ +
Sbjct: 2378 QDILEFNTQLDKLEAWIRDKEMMIHAGETGRDLEHCNALRRKLDDVDSDMRVDDQRIKNI 2437
Query: 3852 NQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDET 3673
NQ+A L S + E ++Q+ E+ N +W++L L A+E+ F+RDVD+T
Sbjct: 2438 NQLADKLVSQDKVE-GKNVQQRRENFNNKWKSLQGALSRYRDLLAGAYEIHVFNRDVDDT 2496
Query: 3672 RDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPE 3493
+ I EK A+ +D GRDL +V+AL+RK E +ERD+ A+ KI+ + A L +P+
Sbjct: 2497 AERIAEKMLAMSVDDTGRDLIAVEALKRKQEAIERDMTAVEQKIREHETSAAALADKYPD 2556
Query: 3492 AAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQ 3313
A I + EL +QWN L + + R E L Y +F ++ ++L W M + + S
Sbjct: 2557 NAINIVEKLDELRKQWNELQNASVKRAEMLKQGYTAHKFTANVKELELWANEMIKRMDSA 2616
Query: 3312 ELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAA---GDIENRLQG 3142
+ EA ++ H E + EID R F+ + G +L+ + ++ +E L+
Sbjct: 2617 SNPATIADCEAQIQLHHERKAEIDGRDLVFRDLQEHGERLVAENRESSVRNDHVEKALRN 2676
Query: 3141 VNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQED--PSGDNVES 2968
+ + K L D+W R L + +LQLF +Q W++ +EAFL +D S VE+
Sbjct: 2677 LEDLNKHLHDSWKGRFRGLKEAHQLQLFKEQADQIVEWLTNKEAFLNNDDLGESFTAVEA 2736
Query: 2967 LIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQ 2788
LIKKHE F+K +++ +I L+ FAE ++ + +++ + ++ ++ R + L +
Sbjct: 2737 LIKKHEAFEKLLHSN--RIGELERFAEEILAESPFEADVIKQRLYAVVSRKDKLLASAET 2794
Query: 2787 KRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHAN 2608
++ KL ES LQQF R E+E W +K QIA +ENYR+P+N+Q K QK AF+AEL AN
Sbjct: 2795 RKQKLQESLQLQQFLRSLYEVEKWTNQKMQIALDENYREPSNLQSKIQKHAAFDAELLAN 2854
Query: 2607 SDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKS 2428
S R+ A+I+ G +LI NA+ + V +L + ++W L + + EK RL EA +
Sbjct: 2855 SGRVTAVIEEGESLI-NAE-HYASSLVQEQLDIVENEWQKLREASREKKERLAEAYEALL 2912
Query: 2427 FMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQAD 2248
F +++D W+ EVE L SEDYG+DLASV NLLKKH +LEAD+ H D ++
Sbjct: 2913 FQRSLEDFNNWMDEVEAQLSSEDYGRDLASVHNLLKKHDMLEADVAHHADTCEQIKATDA 2972
Query: 2247 SLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKE 2068
+L +D F ++ E + RY + + T RRD L +L +HQF RD +DE W+ E
Sbjct: 2973 KMLSSDHFLKDELHESAMVTIKRYHSLHEPTTIRRDNLEDSLQLHQFLRDAEDELLWLNE 3032
Query: 2067 KKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGED 1888
K+ +S D G L VQ+L++KH+ ++ E+ EP +S + +G++++R A +
Sbjct: 3033 KEPQAASKDLGSSLTAVQSLQKKHQALEAEILIQEPIISALVQRGQQMIRDNHYA---VE 3089
Query: 1887 QIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFG 1708
QI+++ L+ +R LT R RL ++ Q F + E E W+ EK+ I+ S ++G
Sbjct: 3090 QIERQCGQLQSKLVNLRHLTNVRRLRLLDAVESQQFYAEANEAEFWLREKKPIISSQDYG 3149
Query: 1707 ENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLI 1528
++ V L KK D Q +L K V + L G+ + IK + D+++ +
Sbjct: 3150 KDEDSVASLQKKLDGLQRELGAFKPTVEKIETLASGLQARGHFDSEKIKSKNDKIQYQFQ 3209
Query: 1527 EIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQE 1348
E+ +A R KL + +F+ + D ++ WI + SE++G D+ V+ L + E
Sbjct: 3210 ELNRLAAEREKKLAEMKKLYEFVREIDDLQEWIEVQMTTAGSEEYGTDVEHVEQLTAQFE 3269
Query: 1347 AFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXX 1168
+F + LNA E + + L+S + I+ + Q W+ L AR+
Sbjct: 3270 SFVSNLNANESR-LTACVAKGEALLSEGNPNRDTIKAKRDETKQLWEELKDLVVARQEAL 3328
Query: 1167 XXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRS 988
F + A +W + + LE I++L H F+
Sbjct: 3329 AGARQVH--------VFDRTADETIAWVNEKISSVLSEDYGHDLETIQSLVRTHEAFEAE 3380
Query: 987 LSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQR 808
L + +E + + +++ + D + W L+ +R+++L + Q
Sbjct: 3381 LGAIKEQLESVVNEAQKLADTYPDAKEHIEVKRDETIEVWSELKDRTVQRKEKLTQAEQL 3440
Query: 807 QEENDKLRREFAKLANAFHAWLTNTRQEMMEAGGTLEEQLDAVERKAKEIKANKGQLRQI 628
Q D+ R AW+ N + A ++ A K AN ++
Sbjct: 3441 QAYFDEYR--------DLMAWI-NEMLAKITAPDLAKDVAGAEALIDKHFLAN-----EV 3486
Query: 627 EEKGAMLE-RNLILDNRYTEHSTVGIAQAWDQLD-QLAMRMQHNLEQQIQAR----NQSG 466
++K A+LE R +LDN + + LD Q ++ ++E I +R +S
Sbjct: 3487 QDKIAVLEQRKRLLDNTIVQR----LEMYELNLDTQRFLKEAEDMESWIISRQMQLKESK 3542
Query: 465 VSEEALREFSMMFKHFDKEKT 403
+ + + ++ KH D EKT
Sbjct: 3543 LGDSIAQVEDLLRKHEDFEKT 3563
Score = 759 bits (1960), Expect = 0.0
Identities = 547/2170 (25%), Positives = 1007/2170 (46%), Gaps = 71/2170 (3%)
Frame = -1
Query: 6888 ASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAE 6709
+++ + KR + ++ + + L+ ++ L F R+CD+ WI++KE + +
Sbjct: 966 SNDSVDKRQKHINGTYDQLQDLAERRRALLEDSICLFRFYRECDDFEKWIKDKEKMLRTD 1025
Query: 6708 DMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVND 6529
D VE +R+F+ F+ +L R+ I+ + V +GHS+ D++ ++ ++
Sbjct: 1026 D---PKGSVETARRQFETFVNDLSASSKRVEAIDSDVEDFVRQGHSQLDKVKARQRQIHQ 1082
Query: 6528 AWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQR 6349
W LN L +++ L GA V+ F R +E + W+ EK L + + G DL VQALQR
Sbjct: 1083 MWEHLNYLKGQKEKSLEGASSVELFYRTCEEAIDWMNEKMTQLDTAEVGPDLKTVQALQR 1142
Query: 6348 KHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKD 6169
+HE ER+LA ++ K+ ++ + + ++P + + +K D + W ++EKA+ R+
Sbjct: 1143 RHENLERELAPVKEKVSRVNLLGNTVKNSYPSERDNVSEKQRDIQNLWQKVQEKAKERRS 1202
Query: 6168 GLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARAD 5989
LE + F + L++WI + + A+E A+DV AE LL+ H++ +I+A D
Sbjct: 1203 RLENAVGQQIFNNSTKALLNWIAECNNQLAAEETARDVETAEKLLKKHKDLGEDINAHDD 1262
Query: 5988 SFNQTASAGQKLVEMG--IPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFY 5815
F Q A GQ+++E + E E+ K+ KL+ E+ L G W + +QC++LQ+F
Sbjct: 1263 EFVQLAKLGQQIIERNPALTEDHEMANKIAKLEAERQRLHGAWLAKEKKLQQCIELQIFN 1322
Query: 5814 RDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKL 5635
R+ ++ + EA+L DLG+SLD VE ++K+H DFE SL AQ++ + E A +L
Sbjct: 1323 READKIDATTKSHEAYLEYDDLGNSLDDVEAIMKRHIDFENSLGAQDKILKNFSEGADRL 1382
Query: 5634 IQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKL 5455
I+ HY A + + R NAL+ S Q F D D++ W+ +K
Sbjct: 1383 IRNNHYNATYIDDRRGQVLARRERVKELAQKRRNALQASKDFQKFSSDVDDLNRWLADKT 1442
Query: 5454 STARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRL 5275
A D+SY D +N+ KLQKH FE+EL+ANE +L + GE +I + + A + + + L
Sbjct: 1443 KIASDESYKDLSNLPRKLQKHKAFERELRANEGQLRMVNKEGESLIKTNNRAGE-VSETL 1501
Query: 5274 RQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSV 5095
+N W +LV + KG +L +A +++ NR IED ++ EL+ + S+ G DL S
Sbjct: 1502 AAINQNWKDLVATSLDKGRRLEQAALQREHNRYIEDSKSKFEELDHALQSKQVGNDLRSC 1561
Query: 5094 QNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPL 4915
+ L K ++E+D +V + ++ E HF+A I + + LQ ++ L+ P
Sbjct: 1562 KELMNKHQVLENDIALWEQKVAELVTTGEEMAHEGHFDANNIQNETKKLQAQFAGLKTPA 1621
Query: 4914 EKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEI 4735
+R+ L ES + ++ +++ EL WI E A S G++L Q+L KK + L AEI
Sbjct: 1622 RQRRDALDESLRFHKFVFELDTELQWINEHLPAAKSEVIGQNLHQAQSLSKKHKKLEAEI 1681
Query: 4734 ANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAH 4555
H I ++A ++I Q H ++++ L W L+ ++ +R L+ SL+A
Sbjct: 1682 EGHQPMINKTLTSAENLINQNHPERAKVKELCNSLEKAWADLQEQSAERSRKLELSLKAQ 1741
Query: 4554 QYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQA 4375
QYLSDA E + W+ E+ ++ S+DYG+D DSA LL KH+ + +L+ + G + ++ A
Sbjct: 1742 QYLSDAGEIETWLGERNNVLRSSDYGRDRDSATKLLTKHKVIELELDTYSGIVSEMGHTA 1801
Query: 4374 S----------------------QCKYQEQPMGQLGRDCVLALYDYQ---EKSPREVSMK 4270
S K ++ GQ + +LY ++ E + E +K
Sbjct: 1802 SAMIAAKHPDSKVIAAKQQLIEKMLKSLQRLAGQRQLRLMESLYRHEYFVESAELEQWIK 1861
Query: 4269 KGD--------------VLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIEPGTAQQHAQQ 4132
+ + +L L N + ++EV + + K++ G +
Sbjct: 1862 EQEQAVNSEDYGHDYEHLLILQNKFDDLKHRIEVGAERFNQCENFAKKLIGGDS-----P 1916
Query: 4131 QVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQ 3952
V+ I +Q + + +Q L+ + R++KL A + ++ R+A + I+ + A A
Sbjct: 1917 YVSEIEKRQELLSNAWQHLLEQLDAREKKLHAAGEIHRFHRDAAEALFRIQDKNA-ALSS 1975
Query: 3951 EIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLN 3772
E+G DL L +K + F+ +L E +LQ + + L + + A I + E++
Sbjct: 1976 ELGKDLNSALALARKHEAFENELVPLEAQLQVLVDDSLRLQTKYPGDNAKAIAAEQENVI 2035
Query: 3771 ARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQ 3592
W L QL ++ ++Q F V + W AL +E+ D AL+
Sbjct: 2036 QYWNVLKEKSALRNDQLHASCDLQHFLTQVRDLMSWATNLRAALQAEEHVSDAAGATALK 2095
Query: 3591 RKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRK 3412
+H+ + ++ A + L+E ++ + Q+ AA ++ + L ++ +L S N +K
Sbjct: 2096 IQHDAIYGEIEAREQTFRELNELSDSMVQTGHYAATEVEEKCSALLDERAKLHSAYNKKK 2155
Query: 3411 EKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRA 3232
L D F+ D + + + +SS + V + ++RH+ + I ++
Sbjct: 2156 ILLEQKIDLFCFMRDAKVIDNISSGQEATLSSSDFGQTVEVVQDQVKRHEAFEKLIQTQD 2215
Query: 3231 ATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYR 3052
+ G +L+ +HY + +I RL+ + E R+ ++D RR L L F R
Sbjct: 2216 EKVAILQEHGRKLVEQNHYDSENIRRRLREIVERRQKVKDLCALRRQKLANALLYAQFIR 2275
Query: 3051 DCEQADTWMSAREAFL---AQEDPSGDNVESLI---KKHEDFDKAINTQEEKIKGLKLFA 2890
DC +A W++ ++ L A N+E + KK + FD +N E +I+ ++
Sbjct: 2276 DCAEAGAWINEKQKKLEADAHSYAGASNMEDKVKKLKKLQAFDAEVNANEGRIREVRDKG 2335
Query: 2889 ESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMT 2710
E LI H + + + +++ WN L L + L E+Q + +F+ D++E W+
Sbjct: 2336 EKLIAKKHECAGEIQDELVKLMQSWNVLLNELASRSRGLKEAQDILEFNTQLDKLEAWIR 2395
Query: 2709 EK-FQIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEA 2533
+K I E RD + +K ++++ + RI I Q + L+ K G
Sbjct: 2396 DKEMMIHAGETGRDLEHCNALRRKLDDVDSDMRVDDQRIKNINQLADKLVSQDKVEGKN- 2454
Query: 2532 AVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYG 2353
V R + N++W L + L A + F V D + E + + +D G
Sbjct: 2455 -VQQRRENFNNKWKSLQGALSRYRDLLAGAYEIHVFNRDVDDTAERIAEKMLAMSVDDTG 2513
Query: 2352 KDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYD 2173
+DL +VE L +K +E D+ A + ++ E A +L + I E+ + +++
Sbjct: 2514 RDLIAVEALKRKQEAIERDMTAVEQKIREHETSAAALADKYPDNAINIVEKLDELRKQWN 2573
Query: 2172 GVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHR 1993
++ + R + L + H+F ++ + E W E + S + + + H
Sbjct: 2574 ELQNASVKRAEMLKQGYTAHKFTANVKELELWANEMIKRMDSASNPATIADCEAQIQLHH 2633
Query: 1992 RIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQ 1813
E+ + ++ GE L+ E+ V D ++K + +LE + D R +
Sbjct: 2634 ERKAEIDGRDLVFRDLQEHGERLVAENRESSVRNDHVEKALRNLEDLNKHLHDSWKGRFR 2693
Query: 1812 RLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQ 1633
L E+ Q F ++ W+ K+ L +D+ GE+ V+ L+KKH+ F + LH
Sbjct: 2694 GLKEAHQLQLFKEQADQIVEWLTNKEAFLNNDDLGESFTAVEALIKKHEAF--EKLLHSN 2751
Query: 1632 RVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWK 1453
R+ +L + ++ A IKQR + +R ++ + AE R KL+++ QF+
Sbjct: 2752 RIGELERFAEEILAESPFEADVIKQRLYAVVSRKDKLLASAETRKQKLQESLQLQQFLRS 2811
Query: 1452 CDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLV 1273
VE W +K Q E++ R+ S++Q + K AFDA L A + + E + L+
Sbjct: 2812 LYEVEKWTNQKMQIALDENY-REPSNLQSKIQKHAAFDAELLA-NSGRVTAVIEEGESLI 2869
Query: 1272 SSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELY--LAFAKKAST 1099
++EH S ++++ V WQ L S ++ ++ E Y L F +
Sbjct: 2870 NAEHYASSLVQEQLDIVENEWQKLREASREKK----------ERLAEAYEALLFQRSLED 2919
Query: 1098 FNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRR------ 937
FN+W + E L+ L + L H + ++ + Q++ D +
Sbjct: 2920 FNNWMDEVEAQLSSEDYGRDLASVHNLLKKHDMLEADVAHHADTCEQIKATDAKMLSSDH 2979
Query: 936 -------------IKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEEN 796
IK ++ P T D LED+ + L + +++ E EL ++E
Sbjct: 2980 FLKDELHESAMVTIKRYHSLHEP-TTIRRDNLEDSLQ-LHQFLRDAEDELL--WLNEKEP 3035
Query: 795 DKLRREFAKLANAFHAWLTNTRQEMMEAGGTLEEQLDA--VERKAKEIKANKGQLRQIEE 622
++ A + + + +EA ++E + + V+R + I+ N + QIE
Sbjct: 3036 QAASKDLGSSLTAVQS--LQKKHQALEAEILIQEPIISALVQRGQQMIRDNHYAVEQIER 3093
Query: 621 KGAMLERNLI 592
+ L+ L+
Sbjct: 3094 QCGQLQSKLV 3103
Score = 682 bits (1761), Expect = 0.0
Identities = 471/1888 (24%), Positives = 885/1888 (45%), Gaps = 45/1888 (2%)
Frame = -1
Query: 7146 KDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENF-RDPSNLQAKIQKHEAF 6970
++ S + +LE + + Q + DA E+ W+ E+ + ++ RD + + KH+
Sbjct: 1724 QEQSAERSRKLELSLKAQQYLSDAGEIETWLGERNNVLRSSDYGRDRDSATKLLTKHKVI 1783
Query: 6969 EAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQA 6790
E E+ ++ ++ + T +AMI H S+ I + + + + + ++L ++
Sbjct: 1784 ELELDTYSGIVSEMGHTASAMIAAKHPDSKVIAAKQQLIEKMLKSLQRLAGQRQLRLMES 1843
Query: 6789 LKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEI 6610
L + + E+ WI+E+E V +ED G D EH+ ILQ KFDD + R N+
Sbjct: 1844 LYRHEYFVESAELEQWIKEQEQAVNSEDYGHDYEHLLILQNKFDDLKHRIEVGAERFNQC 1903
Query: 6609 NQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETL 6430
A KL+ +I K+++ +++AW L R++ L A ++ RF+RDA E L
Sbjct: 1904 ENFAKKLIGGDSPYVSEIEKRQELLSNAWQHLLEQLDAREKKLHAAGEIHRFHRDAAEAL 1963
Query: 6429 AWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHP-D 6253
I +K+ ALSS+ G+DLN+ AL RKHE E +L LE ++ L ++ +L +P D
Sbjct: 1964 FRIQDKNAALSSE-LGKDLNSALALARKHEAFENELVPLEAQLQVLVDDSLRLQTKYPGD 2022
Query: 6252 RAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGAD 6073
A+AI + ++ WN LKEK+ R D L S L FL RDL+SW +++A + A+
Sbjct: 2023 NAKAIAAEQENVIQYWNVLKEKSALRNDQLHASCDLQHFLTQVRDLMSWATNLRAALQAE 2082
Query: 6072 ELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDH 5893
E D AGA AL H GEI+AR +F + +V+ G + EV+EK L
Sbjct: 2083 EHVSDAAGATALKIQHDAIYGEIEAREQTFRELNELSDSMVQTGHYAATEVEEKCSALLD 2142
Query: 5892 EKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIK 5713
E++ L + +++IL EQ +DL F RD + + + QEA L+++D G +++ V+ +K
Sbjct: 2143 ERAKLHSAYNKKKILLEQKIDLFCFMRDAKVIDNISSGQEATLSSSDFGQTVEVVQDQVK 2202
Query: 5712 KHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGN 5533
+HE FEK + Q+EK+ L E KL++ HY ++++ R
Sbjct: 2203 RHEAFEKLIQTQDEKVAILQEHGRKLVEQNHYDSENIRRRLREIVERRQKVKDLCALRRQ 2262
Query: 5532 ALKESYKRQTFDRDCDEMVSWITEKLSTARDD--SYLDPTNIRGK---LQKHINFEQELK 5368
L + F RDC E +WI EK D SY +N+ K L+K F+ E+
Sbjct: 2263 KLANALLYAQFIRDCAEAGAWINEKQKKLEADAHSYAGASNMEDKVKKLKKLQAFDAEVN 2322
Query: 5367 ANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQ 5188
ANE R+ ++R GE++I H A I D L ++ WN L++ + L+EA + +
Sbjct: 2323 ANEGRIREVRDKGEKLIAKKHECAGEIQDELVKLMQSWNVLLNELASRSRGLKEAQDILE 2382
Query: 5187 FNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQ 5008
FN ++ +EAW+ + E + + + G+DL L++K+ ++SD + R+ I QLA
Sbjct: 2383 FNTQLDKLEAWIRDKEMMIHAGETGRDLEHCNALRRKLDDVDSDMRVDDQRIKNINQLAD 2442
Query: 5007 QFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIRE 4828
+ ++ + +++EN ++ +L+ L + + L +++ + RD++D I E
Sbjct: 2443 KLVSQDKVEGKNVQQRRENFNNKWKSLQGALSRYRDLLAGAYEIHVFNRDVDDTAERIAE 2502
Query: 4827 KEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIR 4648
K + GRDLI V+ L +KQ+A+ ++ + +I ++A + + A I
Sbjct: 2503 KMLAMSVDDTGRDLIAVEALKRKQEAIERDMTAVEQKIREHETSAAALADKYPDNAINIV 2562
Query: 4647 DKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDE 4468
+KL +LR W L++ + KR L AH++ ++ E + W +E + S
Sbjct: 2563 EKLDELRKQWNELQNASVKRAEMLKQGYTAHKFTANVKELELWANEMIKRMDSASNPATI 2622
Query: 4467 DSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQPMGQLGRDCVLALYDYQEKSP 4288
EA ++ H ++++ DL++ + + + AL + ++ +
Sbjct: 2623 ADCEAQIQLHHERKAEIDGRDLVFRDLQEHGERLVAENRESSVRNDHVEKALRNLEDLNK 2682
Query: 4287 REVSMKKGDVLTLLNASNRDWWKVEVN-------DRQGFVP-----------AAYVKRIE 4162
KG L A +K + + +++ F+ A +K+ E
Sbjct: 2683 HLHDSWKGRFRGLKEAHQLQLFKEQADQIVEWLTNKEAFLNNDDLGESFTAVEALIKKHE 2742
Query: 4161 P----------GTAQQHAQQ-------QVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEA 4033
G ++ A++ + + I + + + +L+ ETRK+KL+E+
Sbjct: 2743 AFEKLLHSNRIGELERFAEEILAESPFEADVIKQRLYAVVSRKDKLLASAETRKQKLQES 2802
Query: 4032 CKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEM 3853
+ Q LR ++ +W + +A + +QK F +L AN R+ +
Sbjct: 2803 LQLQQFLRSLYEVEKWTNQKMQIALDENYREPSNLQSKIQKHAA-FDAELLANSGRVTAV 2861
Query: 3852 NQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDET 3673
+ +L + +++ +++Q++ + W+ L +L A+E F R +++
Sbjct: 2862 IEEGESLINAEHYASSL-VQEQLDIVENEWQKLREASREKKERLAEAYEALLFQRSLEDF 2920
Query: 3672 RDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPE 3493
+W+ E + L SED+GRDL SV L +KH+ +E D+A D + + ++ S
Sbjct: 2921 NNWMDEVEAQLSSEDYGRDLASVHNLLKKHDMLEADVAHHADTCEQIKATDAKMLSSDHF 2980
Query: 3492 AAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQ 3313
+++++ ++++ L R++ L DS +FL D D + W+ +S+
Sbjct: 2981 LKDELHESAMVTIKRYHSLHEPTTIRRDNLEDSLQLHQFLRDAEDELLWLNEKEPQAASK 3040
Query: 3312 ELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNE 3133
+L + +T ++L ++HQ EI + A Q G Q++ +HYA IE + +
Sbjct: 3041 DLGSSLTAVQSLQKKHQALEAEILIQEPIISALVQRGQQMIRDNHYAVEQIERQCGQLQS 3100
Query: 3132 ARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQED--PSGDNVESLIK 2959
L RR L +E Q FY + +A+ W+ ++ ++ +D D+V SL K
Sbjct: 3101 KLVNLRHLTNVRRLRLLDAVESQQFYAEANEAEFWLREKKPIISSQDYGKDEDSVASLQK 3160
Query: 2958 KHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRF 2779
K + + + + ++ ++ A L H+DS + K D+I ++ L ++
Sbjct: 3161 KLDGLQRELGAFKPTVEKIETLASGLQARGHFDSEKIKSKNDKIQYQFQELNRLAAEREK 3220
Query: 2778 KLGESQTLQQFSRDADEIENWMTEKFQIAQEENY-RDPTNIQQKHQKQQAFEAELHANSD 2602
KL E + L +F R+ D+++ W+ + A E Y D +++Q + ++F + L+AN
Sbjct: 3221 KLAEMKKLYEFVREIDDLQEWIEVQMTTAGSEEYGTDVEHVEQLTAQFESFVSNLNANES 3280
Query: 2601 RIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFM 2422
R+ A + G L+ + A+ W+ L + L A + F
Sbjct: 3281 RLTACVAKGEALLSEGN--PNRDTIKAKRDETKQLWEELKDLVVARQEALAGARQVHVFD 3338
Query: 2421 AAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSL 2242
+ W+ E + SEDYG DL ++++L++ H EA++ A ++++ + +A L
Sbjct: 3339 RTADETIAWVNEKISSVLSEDYGHDLETIQSLVRTHEAFEAELGAIKEQLESVVNEAQKL 3398
Query: 2241 LENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKK 2062
+ + I +R + + +K R++KL++A + +F + D +WI E
Sbjct: 3399 ADTYPDAKEHIEVKRDETIEVWSELKDRTVQRKEKLTQAEQLQAYFDEYRDLMAWINEML 3458
Query: 2061 LLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQI 1882
+++ D +D+ G + L ID ++E Q + L+ + L ++ I
Sbjct: 3459 AKITAPDLAKDVAGAEAL------IDKHFLANEVQDKIAVLEQRKRLL--------DNTI 3504
Query: 1881 KKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGEN 1702
+R+E E + LD Q FL + E+ E+W+ +Q L G++
Sbjct: 3505 VQRLEMYELN--------------LDT----QRFLKEAEDMESWIISRQMQLKESKLGDS 3546
Query: 1701 MAGVQGLLKKHDTFQVDLELHKQRVADL 1618
+A V+ LL+KH+ F+ + +++V L
Sbjct: 3547 IAQVEDLLRKHEDFEKTVAAQEEKVLAL 3574
Score = 653 bits (1684), Expect = 0.0
Identities = 441/1704 (25%), Positives = 805/1704 (46%), Gaps = 110/1704 (6%)
Frame = -1
Query: 5403 LQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKK 5224
++KH ++ A +R +D+ ++ + D + R +V W EL++
Sbjct: 450 VKKHEAISADILARADRFNDLTDMCNELHQENYHGKDRVKKRELEVITKWKELLELLENH 509
Query: 5223 GAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAH 5044
KL + + R I+ + L+ Q ASED G L+ V+ L + L+E
Sbjct: 510 KLKLSQMSSLMNLLREIDATMTTIKALQAQFASEDVGPHLLGVEELLQAHSLLELQVTTL 569
Query: 5043 NDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLF 4864
+ + + F+ ++ + + K L + Y L R+ +L E+ Q
Sbjct: 570 GETQRRYVRQGEAFKRGDYKDTSQLDAKLAELAKLYEELLAMSAARRARLDEARDFYQFV 629
Query: 4863 RDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDM 4684
D E+E W+ +K+++ + +DL V +L +K +AL E+ + ++ A +
Sbjct: 630 EDHENEEGWLVDKQRICKAGITAKDLRAVMSLQQKHKALEDEMKVRKPKSNQITEAGKKL 689
Query: 4683 IQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKE 4504
I H +++ K+ L+++W+ L+ + R+ L+D+ +A+QY +DANEAD+W++EK
Sbjct: 690 IVDKHSRMSDVQGKIDSLQEHWKALEDLVDLRKRQLEDAAEAYQYYADANEADSWLNEKM 749
Query: 4503 PIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQC-------------- 4366
+V S D+G DE SA+ALL++HR L +L A+ G I +L +QA +
Sbjct: 750 ALVASDDFGVDEPSAQALLQRHRDLQGELNAYSGDILNLNQQAEKLIKAGICTLDLSAEP 809
Query: 4365 ---------------------KYQEQPMGQLGRDCVL---------ALYDYQEKSPREVS 4276
++++P+ +L V ALY ++ ++ +
Sbjct: 810 EPVQEMEQEEWVNETRLVPKEVWEDEPVERLEHRTVTENKLLPHVKALYRFEGQN---MK 866
Query: 4275 MKKGDVLTLLNASNRDWWKV-EVNDRQGFVPAAYVKRIEPGTA----------------- 4150
+ KGDV+ L N +N DWW V +++ +GFVPA YVK IEP
Sbjct: 867 VAKGDVMILQNKNNVDWWNVRKLDGTEGFVPANYVKEIEPRPVPCLVRKAEKVKVMQKVK 926
Query: 4149 ---------------------------------QQHAQQQVNSIGGKQSEIEDKYQRLMM 4069
+ A +S+ +Q I Y +L
Sbjct: 927 KTILVKEVIQVKRVRPAKVSQMKPLVKRRAKGDESSAVDSNDSVDKRQKHINGTYDQLQD 986
Query: 4068 LGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKG 3889
L E R+ LE++ ++ RE +D +WIK +E + + VE +++F+ F
Sbjct: 987 LAERRRALLEDSICLFRFYRECDDFEKWIKDKEKMLRTDD---PKGSVETARRQFETFVN 1043
Query: 3888 DLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAH 3709
DL A+ R++ ++ G ++ +++ + ++ W L L A
Sbjct: 1044 DLSASSKRVEAIDSDVEDFVRQGHSQLD-KVKARQRQIHQMWEHLNYLKGQKEKSLEGAS 1102
Query: 3708 EVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLD 3529
V+ F+R +E DW+ EK LD+ + G DL++VQALQR+HE +ER+LA + +K+ ++
Sbjct: 1103 SVELFYRTCEEAIDWMNEKMTQLDTAEVGPDLKTVQALQRRHENLERELAPVKEKVSRVN 1162
Query: 3528 EKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQ 3349
N ++ S+P + + + QR++ W ++ KA R+ +L ++ Q F + + L+
Sbjct: 1163 LLGNTVKNSYPSERDNVSEKQRDIQNLWQKVQEKAKERRSRLENAVGQQIFNNSTKALLN 1222
Query: 3348 WIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAA 3169
WIA N ++++E A DV AE LL++H++ +I++ F + G Q++ +
Sbjct: 1223 WIAECNNQLAAEETARDVETAEKLLKKHKDLGEDINAHDDEFVQLAKLGQQIIERNPALT 1282
Query: 3168 GDIE--NRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQE 2995
D E N++ + R+ L AW+A+ L QC+ELQ+F R+ ++ D + EA+L +
Sbjct: 1283 EDHEMANKIAKLEAERQRLHGAWLAKEKKLQQCIELQIFNREADKIDATTKSHEAYLEYD 1342
Query: 2994 D--PSGDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILD 2821
D S D+VE+++K+H DF+ ++ Q++ +K A+ LI+NNHY++ + +R Q+L
Sbjct: 1343 DLGNSLDDVEAIMKRHIDFENSLGAQDKILKNFSEGADRLIRNNHYNATYIDDRRGQVLA 1402
Query: 2820 RWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNIQQKHQK 2641
R +KE ++R L S+ Q+FS D D++ W+ +K +IA +E+Y+D +N+ +K QK
Sbjct: 1403 RRERVKELAQKRRNALQASKDFQKFSSDVDDLNRWLADKTKIASDESYKDLSNLPRKLQK 1462
Query: 2640 QQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKS 2461
+AFE EL AN ++ + + G +LI+ G VS L A+N W LV T+ +K
Sbjct: 1463 HKAFERELRANEGQLRMVNKEGESLIKTNNRAG---EVSETLAAINQNWKDLVATSLDKG 1519
Query: 2460 YRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQ 2281
RL++A Q+ ++D + E++ LQS+ G DL S + L+ KH +LE DI +
Sbjct: 1520 RRLEQAALQREHNRYIEDSKSKFEELDHALQSKQVGNDLRSCKELMNKHQVLENDIALWE 1579
Query: 2280 DRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFR 2101
+V E+ + + F I K + ++ G+K A RRD L ++L H+F
Sbjct: 1580 QKVAELVTTGEEMAHEGHFDANNIQNETKKLQAQFAGLKTPARQRRDALDESLRFHKFVF 1639
Query: 2100 DIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELL 1921
++D E WI E S+ G++L Q+L +KH++++ E+ H+P ++ E L+
Sbjct: 1640 ELDTELQWINEHLPAAKSEVIGQNLHQAQSLSKKHKKLEAEIEGHQPMINKTLTSAENLI 1699
Query: 1920 RSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNE 1741
+ ++K+ LE++W +++ + R ++L+ S Q +L D E E W+ E
Sbjct: 1700 N---QNHPERAKVKELCNSLEKAWADLQEQSAERSRKLELSLKAQQYLSDAGEIETWLGE 1756
Query: 1740 KQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIK 1561
+ +L S ++G + LL KH +++L+ + V+++ + +I + + I
Sbjct: 1757 RNNVLRSSDYGRDRDSATKLLTKHKVIELELDTYSGIVSEMGHTASAMIAAKHPDSKVIA 1816
Query: 1560 QRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDL 1381
+ + L ++ +A R +L ++ ++ + +E WI E+EQ V SED+G D
Sbjct: 1817 AKQQLIEKMLKSLQRLAGQRQLRLMESLYRHEYFVESAELEQWIKEQEQAVNSEDYGHDY 1876
Query: 1380 SSVQILLTKQEAFDAGLNAFEHEGIQRITELKD---QLVSSEHQQSPAIEKRHTNVIQRW 1210
+ IL Q FD + E G +R + ++ +L+ + IEKR + W
Sbjct: 1877 EHLLIL---QNKFDDLKHRIE-VGAERFNQCENFAKKLIGGDSPYVSEIEKRQELLSNAW 1932
Query: 1209 QNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEE 1030
Q+LL +AR E++ F + A+ ++ L+ + L
Sbjct: 1933 QHLLEQLDAREKKLHAAG-------EIH-RFHRDAAEALFRIQDKNAALSSELG-KDLNS 1983
Query: 1029 IRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRI 850
AL H F+ L E + L D R+++ G N + A ++ +
Sbjct: 1984 ALALARKHEAFENELVPLEAQLQVLVDDSLRLQTKYPGDNAK---AIAAEQENVIQYWNV 2040
Query: 849 IKEREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTR------QEMMEAGG--TLEE 694
+KE+ R Q D + F +W TN R + + +A G L+
Sbjct: 2041 LKEK--SALRNDQLHASCD--LQHFLTQVRDLMSWATNLRAALQAEEHVSDAAGATALKI 2096
Query: 693 QLDAVERKAKEIKANKGQLRQIEE 622
Q DA+ EI+A + R++ E
Sbjct: 2097 QHDAI---YGEIEAREQTFRELNE 2117
Score = 595 bits (1534), Expect = e-168
Identities = 400/1371 (29%), Positives = 650/1371 (47%), Gaps = 52/1371 (3%)
Frame = -1
Query: 7200 ADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQT--AQE 7027
+++I +R +E++ KD +R +L A + F RD E WI EK + A
Sbjct: 2236 SENIRRRLREIVERRQKVKDLCALRRQKLANALLYAQFIRDCAEAGAWINEKQKKLEADA 2295
Query: 7026 ENFRDPSNLQAKIQKH---EAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEE 6856
++ SN++ K++K +AF+AEV A+ I + G +I H + I+ L +
Sbjct: 2296 HSYAGASNMEDKVKKLKKLQAFDAEVNANEGRIREVRDKGEKLIAKKHECAGEIQDELVK 2355
Query: 6855 LHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEI 6676
L W + L++A +L F Q D++ WIR+KE + A + G DLEH
Sbjct: 2356 LMQSWNVLLNELASRSRGLKEAQDILEFNTQLDKLEAWIRDKEMMIHAGETGRDLEHCNA 2415
Query: 6675 LQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAAT 6496
L+RK DD ++ RI INQ ADKLV + E + ++R++ N+ W L +
Sbjct: 2416 LRRKLDDVDSDMRVDDQRIKNINQLADKLVSQDKVEGKNVQQRRENFNNKWKSLQGALSR 2475
Query: 6495 RKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAA 6316
++ L GA+++ FNRD D+T I EK LA+S DD GRDL V+AL+RK E ERD+ A
Sbjct: 2476 YRDLLAGAYEIHVFNRDVDDTAERIAEKMLAMSVDDTGRDLIAVEALKRKQEAIERDMTA 2535
Query: 6315 LEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRF 6136
+E K+ + E A LA+ +PD A I +K D+ + WN L+ + R + L++ + H+F
Sbjct: 2536 VEQKIREHETSAAALADKYPDNAINIVEKLDELRKQWNELQNASVKRAEMLKQGYTAHKF 2595
Query: 6135 LADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQK 5956
A+ ++L W +M + + +A EA ++ H E K EID R F G++
Sbjct: 2596 TANVKELELWANEMIKRMDSASNPATIADCEAQIQLHHERKAEIDGRDLVFRDLQEHGER 2655
Query: 5955 LVEMGIPES---PEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWM 5785
LV S V++ L L+ L W+ R ++ LQLF +Q W+
Sbjct: 2656 LVAENRESSVRNDHVEKALRNLEDLNKHLHDSWKGRFRGLKEAHQLQLFKEQADQIVEWL 2715
Query: 5784 NKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADD 5605
+EAFL N DLG+S +VE LIKKHE FEK L +I L+ FA +++ + AD
Sbjct: 2716 TNKEAFLNNDDLGESFTAVEALIKKHEAFEKLL--HSNRIGELERFAEEILAESPFEADV 2773
Query: 5604 VAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLD 5425
+ + R L+ES + Q F R E+ W +K+ A D++Y +
Sbjct: 2774 IKQRLYAVVSRKDKLLASAETRKQKLQESLQLQQFLRSLYEVEKWTNQKMQIALDENYRE 2833
Query: 5424 PTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNEL 5245
P+N++ K+QKH F+ EL AN R+ + GE +I++ H+A+ + ++L V N W +L
Sbjct: 2834 PSNLQSKIQKHAAFDAELLANSGRVTAVIEEGESLINAEHYASSLVQEQLDIVENEWQKL 2893
Query: 5244 VDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLI 5065
+A+ +K +L EA F R++ED W+ E+E Q++SEDYG+DL SV NL KK ++
Sbjct: 2894 REASREKKERLAEAYEALLFQRSLEDFNNWMDEVEAQLSSEDYGRDLASVHNLLKKHDML 2953
Query: 5064 ESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGES 4885
E+D H D + IK + +HF + +RY++L +P R+ L +S
Sbjct: 2954 EADVAHHADTCEQIKATDAKMLSSDHFLKDELHESAMVTIKRYHSLHEPTTIRRDNLEDS 3013
Query: 4884 HQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESV 4705
Q +Q RD EDEL W+ EKE A S + G L VQ+L KK QAL AEI + I ++
Sbjct: 3014 LQLHQFLRDAEDELLWLNEKEPQAASKDLGSSLTAVQSLQKKHQALEAEILIQEPIISAL 3073
Query: 4704 SSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEAD 4525
MI+ H+ +I + QL+ L+ RR L D++++ Q+ ++ANEA+
Sbjct: 3074 VQRGQQMIRDNHYAVEQIERQCGQLQSKLVNLRHLTNVRRLRLLDAVESQQFYAEANEAE 3133
Query: 4524 AWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQAS--------- 4372
W+ EK+PI+ S DYGKDEDS +L KK L +L AFK T+E + AS
Sbjct: 3134 FWLREKKPIISSQDYGKDEDSVASLQKKLDGLQRELGAFKPTVEKIETLASGLQARGHFD 3193
Query: 4371 ---------QCKYQEQPMGQLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWK 4219
+ +YQ Q + +L E+ + MKK ++W +
Sbjct: 3194 SEKIKSKNDKIQYQFQELNRLA----------AEREKKLAEMKKLYEFVREIDDLQEWIE 3243
Query: 4218 VEVNDRQGFVPAAYVKRIEPGTAQ--------------------------QHAQQQVNSI 4117
V++ V+ +E TAQ ++I
Sbjct: 3244 VQMTTAGSEEYGTDVEHVEQLTAQFESFVSNLNANESRLTACVAKGEALLSEGNPNRDTI 3303
Query: 4116 GGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTD 3937
K+ E + ++ L L R+ L A + + R A++ W+ + + ++ G D
Sbjct: 3304 KAKRDETKQLWEELKDLVVARQEALAGARQVHVFDRTADETIAWVNEKISSVLSEDYGHD 3363
Query: 3936 LEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRA 3757
LE ++ L + + F+ +L A + +L+ + A L + I + ++ W
Sbjct: 3364 LETIQSLVRTHEAFEAELGAIKEQLESVVNEAQKLADT-YPDAKEHIEVKRDETIEVWSE 3422
Query: 3756 LXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEG 3577
L +L A ++Q + + + WI E + + D +D+ +AL KH
Sbjct: 3423 LKDRTVQRKEKLTQAEQLQAYFDEYRDLMAWINEMLAKITAPDLAKDVAGAEALIDKHFL 3482
Query: 3576 VERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLD 3397
+ DKI L+++ L + + E +Y+L
Sbjct: 3483 ANE----VQDKIAVLEQRKRLLDNTIVQRLE-MYEL------------------------ 3513
Query: 3396 SYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEI 3244
+ D QRFL + D+ WI S + +L + + E LL +H+++ +
Sbjct: 3514 NLDTQRFLKEAEDMESWIISRQMQLKESKLGDSIAQVEDLLRKHEDFEKTV 3564
Score = 410 bits (1053), Expect = e-112
Identities = 387/1753 (22%), Positives = 769/1753 (43%), Gaps = 73/1753 (4%)
Frame = -1
Query: 7185 QRRQEVLGH-YSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENFRDP 7009
++RQE+L + + + + +L A + F RDA E I +K E +D
Sbjct: 1922 EKRQELLSNAWQHLLEQLDAREKKLHAAGEIHRFHRDAAEALFRIQDKNAALSSELGKDL 1981
Query: 7008 SNLQAKIQKHEAFEAE-VQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXX 6832
++ A +KHEAFE E V A+ +D + ++ ++ I E + W
Sbjct: 1982 NSALALARKHEAFENELVPLEAQLQVLVDDSLRLQTKYPGDNAKAIAAEQENVIQYWNVL 2041
Query: 6831 XXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDF 6652
+ +L + L HF+ Q +++ W + AE+ D L+ + D
Sbjct: 2042 KEKSALRNDQLHASCDLQHFLTQVRDLMSWATNLRAALQAEEHVSDAAGATALKIQHDAI 2101
Query: 6651 LKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGA 6472
E+ + E+N+ +D +V+ GH ++ +K + D +L++ +K L
Sbjct: 2102 YGEIEAREQTFRELNELSDSMVQTGHYAATEVEEKCSALLDERAKLHSAYNKKKILLEQK 2161
Query: 6471 HQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQL 6292
+ F RDA ++ LSS D+G+ + VQ ++HE E+ + + K+ L
Sbjct: 2162 IDLFCFMRDAKVIDNISSGQEATLSSSDFGQTVEVVQDQVKRHEAFEKLIQTQDEKVAIL 2221
Query: 6291 EKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLI 6112
++ KL E + +E I ++ + +K+ R+ L + +F+ D +
Sbjct: 2222 QEHGRKLVEQNHYDSENIRRRLREIVERRQKVKDLCALRRQKLANALLYAQFIRDCAEAG 2281
Query: 6111 SWIGDMKAVIGADELAKDVAGAEAL------LESHQEHKGEIDARADSFNQTASAGQKLV 5950
+WI + + + AD A AGA + L+ Q E++A + G+KL+
Sbjct: 2282 AWINEKQKKLEAD--AHSYAGASNMEDKVKKLKKLQAFDAEVNANEGRIREVRDKGEKLI 2339
Query: 5949 EMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEA 5770
+ E+Q++L KL + LL R ++ D+ F ++ E W+ +E
Sbjct: 2340 AKKHECAGEIQDELVKLMQSWNVLLNELASRSRGLKEAQDILEFNTQLDKLEAWIRDKEM 2399
Query: 5769 FLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXX 5590
+ + G L+ L +K +D + + +++I +++ A KL+ +V +
Sbjct: 2400 MIHAGETGRDLEHCNALRRKLDDVDSDMRVDDQRIKNINQLADKLVSQDKVEGKNVQQRR 2459
Query: 5589 XXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEK-LSTARDDSYLDPTNI 5413
+ L +Y+ F+RD D+ I EK L+ + DD+ D +
Sbjct: 2460 ENFNNKWKSLQGALSRYRDLLAGAYEIHVFNRDVDDTAERIAEKMLAMSVDDTGRDLIAV 2519
Query: 5412 RGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDAT 5233
+K E+++ A E ++ + ++ + D A +I ++L ++ WNEL +A+
Sbjct: 2520 EALKRKQEAIERDMTAVEQKIREHETSAAALADKYPDNAINIVEKLDELRKQWNELQNAS 2579
Query: 5232 NKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDF 5053
K+ L++ +F N++++E W +E+ + D + ++ + + +I L
Sbjct: 2580 VKRAEMLKQGYTAHKFTANVKELELWANEM---IKRMDSASNPATIADCEAQIQL----- 2631
Query: 5052 NAHNDR---VDGIKQLAQQFQE----------EEHFNAPVIVRKQENLQQRYNALRDPLE 4912
H++R +DG + + QE E + + NL+ L D +
Sbjct: 2632 --HHERKAEIDGRDLVFRDLQEHGERLVAENRESSVRNDHVEKALRNLEDLNKHLHDSWK 2689
Query: 4911 KRKRKLGESHQGNQLFRDIEDELA-WIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEI 4735
R R L E+HQ QLF++ D++ W+ KE + + G V+ LIKK +A E
Sbjct: 2690 GRFRGLKEAHQ-LQLFKEQADQIVEWLTNKEAFLNNDDLGESFTAVEALIKKHEAF--EK 2746
Query: 4734 ANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAH 4555
H ++I + A +++ + F A I+ +L + L + AE R+ L +SLQ
Sbjct: 2747 LLHSNRIGELERFAEEILAESPFEADVIKQRLYAVVSRKDKLLASAETRKQKLQESLQLQ 2806
Query: 4554 QYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQA 4375
Q+L E + W ++K I +Y ++ + ++ ++KH A ++L A G + + ++
Sbjct: 2807 QFLRSLYEVEKWTNQKMQIALDENY-REPSNLQSKIQKHAAFDAELLANSGRVTAVIEEG 2865
Query: 4374 SQCKYQEQPMGQLGRDCVLALYDYQEKSPREVSMKKGDVLT------LLNASNRDW--WK 4219
E L ++ L + + + + RE S +K + L L S D+ W
Sbjct: 2866 ESLINAEHYASSLVQE-QLDIVENEWQKLREASREKKERLAEAYEALLFQRSLEDFNNWM 2924
Query: 4218 VEV-----NDRQGFVPAAYVKRIE-----PGTAQQHAQ--QQVNSIGGK--------QSE 4099
EV ++ G A+ ++ HA +Q+ + K + E
Sbjct: 2925 DEVEAQLSSEDYGRDLASVHNLLKKHDMLEADVAHHADTCEQIKATDAKMLSSDHFLKDE 2984
Query: 4098 IED-------KYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGT 3940
+ + +Y L R+ LE++ + +Q LR+A D W+ +E AA +++G+
Sbjct: 2985 LHESAMVTIKRYHSLHEPTTIRRDNLEDSLQLHQFLRDAEDELLWLNEKEPQAASKDLGS 3044
Query: 3939 DLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQT------ETAVRIRQQIED 3778
L V+ LQKK + E+ +QE I +AL GQ +I +Q
Sbjct: 3045 SLTAVQSLQKKHQALEA-----EILIQE--PIISALVQRGQQMIRDNHYAVEQIERQCGQ 3097
Query: 3777 LNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQA 3598
L ++ L +L A E Q+F+ + +E W++EK + S+D+G+D SV +
Sbjct: 3098 LQSKLVNLRHLTNVRRLRLLDAVESQQFYAEANEAEFWLREKKPIISSQDYGKDEDSVAS 3157
Query: 3597 LQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANN 3418
LQ+K +G++R+L A ++ ++ A+ L+ +E+I ++ Q+ L A
Sbjct: 3158 LQKKLDGLQRELGAFKPTVEKIETLASGLQARGHFDSEKIKSKNDKIQYQFQELNRLAAE 3217
Query: 3417 RKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDS 3238
R++KL + F+ + DL +WI S+E DV E L + + + + +++
Sbjct: 3218 REKKLAEMKKLYEFVREIDDLQEWIEVQMTTAGSEEYGTDVEHVEQLTAQFESFVSNLNA 3277
Query: 3237 RAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLF 3058
+ A G LL+ + I+ + + + L+D VAR+ L ++ +F
Sbjct: 3278 NESRLTACVAKGEALLSEGNPNRDTIKAKRDETKQLWEELKDLVVARQEALAGARQVHVF 3337
Query: 3057 YRDCEQADTWMSAREAFLAQEDPSGD--NVESLIKKHEDFDKAINTQEEKIKGLKLFAES 2884
R ++ W++ + + + ED D ++SL++ HE F+ + +E+++ + A+
Sbjct: 3338 DRTADETIAWVNEKISSVLSEDYGHDLETIQSLVRTHEAFEAELGAIKEQLESVVNEAQK 3397
Query: 2883 LIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEK 2704
L + KRD+ ++ W+ LK+ +Q++ KL +++ LQ + + ++ W+ E
Sbjct: 3398 LADTYPDAKEHIEVKRDETIEVWSELKDRTVQRKEKLTQAEQLQAYFDEYRDLMAWINEM 3457
Query: 2703 F-QIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAV 2527
+I + +D + K F A + D+I A+++ L++N +
Sbjct: 3458 LAKITAPDLAKDVAGAEALIDKH--FLA--NEVQDKI-AVLEQRKRLLDN--------TI 3504
Query: 2526 SARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKD 2347
RL + ++L + T + F+ +D+E W+ ++ L+ G
Sbjct: 3505 VQRL----EMYELNLDT--------------QRFLKEAEDMESWIISRQMQLKESKLGDS 3546
Query: 2346 LASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLEN------DQFQGQQIAERRKLIA 2185
+A VE+LL+KH E + A +++V + + +LLE + Q +IAE+ ++
Sbjct: 3547 IAQVEDLLRKHEDFEKTVAAQEEKV--LALKRITLLEQKFKKQLEAEQAARIAEKERIER 3604
Query: 2184 DRYDGVKKMATDR 2146
+R++ +K+ R
Sbjct: 3605 ERHEALKQKEVQR 3617
Score = 405 bits (1040), Expect = e-110
Identities = 378/1827 (20%), Positives = 771/1827 (41%), Gaps = 58/1827 (3%)
Frame = -1
Query: 7116 LEEARQFQYFKRDADELNVWILEKLQTAQEENF-RDPSNLQAKIQKHEAFEAEVQAHAKT 6940
+E + +YF A EL WI E+ Q E++ D +L K + + ++ A+
Sbjct: 1841 MESLYRHEYFVESA-ELEQWIKEQEQAVNSEDYGHDYEHLLILQNKFDDLKHRIEVGAER 1899
Query: 6939 IANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQC 6760
+ +I + I+KR E L W + KL A ++ F R
Sbjct: 1900 FNQCENFAKKLIGGDSPYVSEIEKRQELLSNAWQHLLEQLDAREKKLHAAGEIHRFHRDA 1959
Query: 6759 DEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEE 6580
E L+ I++K +++E +G DL L RK + F EL + ++ + + +L +
Sbjct: 1960 AEALFRIQDKNAALSSE-LGKDLNSALALARKHEAFENELVPLEAQLQVLVDDSLRLQTK 2018
Query: 6579 GHSEHDQ-IYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLA 6403
++ + I ++++V W+ L +A R + L + +Q F + ++W A
Sbjct: 2019 YPGDNAKAIAAEQENVIQYWNVLKEKSALRNDQLHASCDLQHFLTQVRDLMSWATNLRAA 2078
Query: 6402 LSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKND 6223
L ++++ D AL+ +H+ ++ A E +L + + + +T A + +K
Sbjct: 2079 LQAEEHVSDAAGATALKIQHDAIYGEIEAREQTFRELNELSDSMVQTGHYAATEVEEKCS 2138
Query: 6222 DTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAE 6043
L +K LE+ L F+ D + + + +A + + + + V +
Sbjct: 2139 ALLDERAKLHSAYNKKKILLEQKIDLFCFMRDAKVIDNISSGQEATLSSSDFGQTVEVVQ 2198
Query: 6042 ALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWE 5863
++ H+ + I + + G+KLVE +S ++ +L ++ + + L
Sbjct: 2199 DQVKRHEAFEKLIQTQDEKVAILQEHGRKLVEQNHYDSENIRRRLREIVERRQKVKDLCA 2258
Query: 5862 ERRILYEQCMDLQLFYRDTEQAETWMNKQEAFL---ANTDLGDS-LDSVEHLIKKHEDFE 5695
RR + F RD +A W+N+++ L A++ G S ++ +KK + F+
Sbjct: 2259 LRRQKLANALLYAQFIRDCAEAGAWINEKQKKLEADAHSYAGASNMEDKVKKLKKLQAFD 2318
Query: 5694 KSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESY 5515
+ A E +I + + KLI +H A ++ + R LKE+
Sbjct: 2319 AEVNANEGRIREVRDKGEKLIAKKHECAGEIQDELVKLMQSWNVLLNELASRSRGLKEAQ 2378
Query: 5514 KRQTFDRDCDEMVSWITEKL------STARDDSYLDPTNIRGKLQKHINFEQELKANENR 5353
F+ D++ +WI +K T RD + + +R KL + + +++ ++ R
Sbjct: 2379 DILEFNTQLDKLEAWIRDKEMMIHAGETGRDLEHCNA--LRRKLD---DVDSDMRVDDQR 2433
Query: 5352 LDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNI 5173
+ +I ++++ ++ R NN W L A ++ L A FNR++
Sbjct: 2434 IKNINQLADKLVSQDKVEGKNVQQRRENFNNKWKSLQGALSRYRDLLAGAYEIHVFNRDV 2493
Query: 5172 EDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEE 4993
+D ++E ++ +D G+DL++V+ L++K IE D A ++ + A ++
Sbjct: 2494 DDTAERIAEKMLAMSVDDTGRDLIAVEALKRKQEAIERDMTAVEQKIREHETSAAALADK 2553
Query: 4992 EHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVA 4813
NA IV K + L++++N L++ KR L + + ++ ++++ W E +
Sbjct: 2554 YPDNAINIVEKLDELRKQWNELQNASVKRAEMLKQGYTAHKFTANVKELELWANEMIKRM 2613
Query: 4812 GSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLA---PEIRDK 4642
S + + + I+ AEI D + ++ + + +
Sbjct: 2614 DSASNPATIADCEAQIQLHHERKAEIDGRDLVFRDLQEHGERLVAENRESSVRNDHVEKA 2673
Query: 4641 LAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDS 4462
L L D + L + R L ++ Q + A++ W++ KE + + D G+ +
Sbjct: 2674 LRNLEDLNKHLHDSWKGRFRGLKEAHQLQLFKEQADQIVEWLTNKEAFLNNDDLGESFTA 2733
Query: 4461 AEALLKKHRAL--------LSDLEAFKGTI----------------------EDLRKQAS 4372
EAL+KKH A + +LE F I + L A
Sbjct: 2734 VEALIKKHEAFEKLLHSNRIGELERFAEEILAESPFEADVIKQRLYAVVSRKDKLLASAE 2793
Query: 4371 QCKYQEQPMGQLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGF 4192
K + Q QL + + +LY+ ++ + +++ + + + K D +
Sbjct: 2794 TRKQKLQESLQL-QQFLRSLYEVEKWTNQKMQIALDENYREPSNLQSKIQKHAAFDAELL 2852
Query: 4191 VPAAYVKR-IEPGTAQQHAQQQVNSIGGKQSEI-EDKYQRLMMLGETRKRKLEEACKGYQ 4018
+ V IE G + +A+ +S+ +Q +I E+++Q+L +K +L EA +
Sbjct: 2853 ANSGRVTAVIEEGESLINAEHYASSLVQEQLDIVENEWQKLREASREKKERLAEAYEALL 2912
Query: 4017 LLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIAT 3838
R D W+ EA + ++ G DL V L KK D + D+ + +++
Sbjct: 2913 FQRSLEDFNNWMDEVEAQLSSEDYGRDLASVHNLLKKHDMLEADVAHHADTCEQIKATDA 2972
Query: 3837 ALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQ 3658
+ S + + R+ +L L + ++ +F RD ++ W+
Sbjct: 2973 KMLSSDHF-LKDELHESAMVTIKRYHSLHEPTTIRRDNLEDSLQLHQFLRDAEDELLWLN 3031
Query: 3657 EKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQI 3478
EK+ S+D G L +VQ+LQ+KH+ +E ++ I +L ++ ++ + + A EQI
Sbjct: 3032 EKEPQAASKDLGSSLTAVQSLQKKHQALEAEILIQEPIISALVQRGQQMIRDNHYAVEQI 3091
Query: 3477 YDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELAND 3298
+L + L N R+ +LLD+ + Q+F ++ + W+ ++SSQ+ D
Sbjct: 3092 ERQCGQLQSKLVNLRHLTNVRRLRLLDAVESQQFYAEANEAEFWLREKKPIISSQDYGKD 3151
Query: 3297 VTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGL 3118
+L ++ + E+ + T + + + L H+ + I+++ + + L
Sbjct: 3152 EDSVASLQKKLDGLQRELGAFKPTVEKIETLASGLQARGHFDSEKIKSKNDKIQYQFQEL 3211
Query: 3117 EDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGD--NVESLIKKHEDF 2944
R L + +L F R+ + W+ + E+ D +VE L + E F
Sbjct: 3212 NRLAAEREKKLAEMKKLYEFVREIDDLQEWIEVQMTTAGSEEYGTDVEHVEQLTAQFESF 3271
Query: 2943 DKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGES 2764
+N E ++ E+L+ + + + KRD+ W LK+ ++ ++ L +
Sbjct: 3272 VSNLNANESRLTACVAKGEALLSEGNPNRDTIKAKRDETKQLWEELKDLVVARQEALAGA 3331
Query: 2763 QTLQQFSRDADEIENWMTEKFQIAQEENY-RDPTNIQQKHQKQQAFEAELHANSDRIAAI 2587
+ + F R ADE W+ EK E+Y D IQ + +AFEAEL A +++ ++
Sbjct: 3332 RQVHVFDRTADETIAWVNEKISSVLSEDYGHDLETIQSLVRTHEAFEAELGAIKEQLESV 3391
Query: 2586 IQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKD 2407
+ L + + + + + W L T ++ +L +A + +++ +D
Sbjct: 3392 VNEAQKLADTYP--DAKEHIEVKRDETIEVWSELKDRTVQRKEKLTQAEQLQAYFDEYRD 3449
Query: 2406 LEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQ 2227
L W+ E+ + + D KD+A E L+ KH L QD++ + EQ LL+N
Sbjct: 3450 LMAWINEMLAKITAPDLAKDVAGAEALIDKHFLANEV----QDKIAVL-EQRKRLLDNTI 3504
Query: 2226 FQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSS 2047
Q ++ E L+ +F ++ +D ESWI +++ +
Sbjct: 3505 VQRLEMYELN------------------------LDTQRFLKEAEDMESWIISRQMQLKE 3540
Query: 2046 DDYGRDLPGVQNLRRKHRRIDTELASHEPQV------SLVKLKGEELLRSAAEAGVGEDQ 1885
G + V++L RKH + +A+ E +V +L++ K ++ L + A + E +
Sbjct: 3541 SKLGDSIAQVEDLLRKHEDFEKTVAAQEEKVLALKRITLLEQKFKKQLEAEQAARIAEKE 3600
Query: 1884 --IKKRMEDLEQSWGQIRDLTGNRHQR 1810
++R E L+Q +++ +T R +R
Sbjct: 3601 RIERERHEALKQK--EVQRITEERRRR 3625
Score = 352 bits (902), Expect = 1e-94
Identities = 279/1135 (24%), Positives = 509/1135 (44%), Gaps = 18/1135 (1%)
Frame = -1
Query: 7194 DIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEK-LQTAQEENF 7018
++ QRR+ + + RD L A + F RD D+ I EK L + ++
Sbjct: 2454 NVQQRRENFNNKWKSLQGALSRYRDLLAGAYEIHVFNRDVDDTAERIAEKMLAMSVDDTG 2513
Query: 7017 RDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWX 6838
RD ++A +K EA E ++ A + I + + A+ + +I ++L+EL W
Sbjct: 2514 RDLIAVEALKRKQEAIERDMTAVEQKIREHETSAAALADKYPDNAINIVEKLDELRKQWN 2573
Query: 6837 XXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFD 6658
+ L+Q F E+ W E + + + E +
Sbjct: 2574 ELQNASVKRAEMLKQGYTAHKFTANVKELELWANEMIKRMDSASNPATIADCEAQIQLHH 2633
Query: 6657 DFLKELGNHQYRINEINQAADKLVEEGHSE---HDQIYKKRDDVNDAWHRLNTLAATRKE 6487
+ E+ ++ + ++LV E +D + K ++ D L+ R
Sbjct: 2634 ERKAEIDGRDLVFRDLQEHGERLVAENRESSVRNDHVEKALRNLEDLNKHLHDSWKGRFR 2693
Query: 6486 GLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEG 6307
GL AHQ+Q F AD+ + W+ K+ L++DD G V+AL +KHE E+ L +
Sbjct: 2694 GLKEAHQLQLFKEQADQIVEWLTNKEAFLNNDDLGESFTAVEALIKKHEAFEKLLHS--N 2751
Query: 6306 KMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLAD 6127
++ +LE+ A ++ P A+ I Q+ + + L A+ RK L+ S QL +FL
Sbjct: 2752 RIGELERFAEEILAESPFEADVIKQRLYAVVSRKDKLLASAETRKQKLQESLQLQQFLRS 2811
Query: 6126 YRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVE 5947
++ W + K I DE ++ + ++ ++ H E+ A + G+ L+
Sbjct: 2812 LYEVEKWT-NQKMQIALDENYREPSNLQSKIQKHAAFDAELLANSGRVTAVIEEGESLIN 2870
Query: 5946 MGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAF 5767
S VQE+L+ +++E L E++ + + LF R E WM++ EA
Sbjct: 2871 AEHYASSLVQEQLDIVENEWQKLREASREKKERLAEAYEALLFQRSLEDFNNWMDEVEAQ 2930
Query: 5766 LANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXX 5587
L++ D G L SV +L+KKH+ E +A + + K++ H+ D++ E
Sbjct: 2931 LSSEDYGRDLASVHNLLKKHDMLEADVAHHADTCEQIKATDAKMLSSDHFLKDELHESAM 2990
Query: 5586 XXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKL-STARDDSYLDPTNIR 5410
R + L++S + F RD ++ + W+ EK A D T ++
Sbjct: 2991 VTIKRYHSLHEPTTIRRDNLEDSLQLHQFLRDAEDELLWLNEKEPQAASKDLGSSLTAVQ 3050
Query: 5409 GKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATN 5230
+KH E E+ E + + G+Q+I H+A + I + Q+ + L TN
Sbjct: 3051 SLQKKHQALEAEILIQEPIISALVQRGQQMIRDNHYAVEQIERQCGQLQSKLVNLRHLTN 3110
Query: 5229 KKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFN 5050
+ +L +A QQF + E WL E + ++S+DYGKD SV +LQKK+ ++ +
Sbjct: 3111 VRRLRLLDAVESQQFYAEANEAEFWLREKKPIISSQDYGKDEDSVASLQKKLDGLQRELG 3170
Query: 5049 AHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQ 4870
A V+ I+ LA Q HF++ I K + +Q ++ L +R++KL E + +
Sbjct: 3171 AFKPTVEKIETLASGLQARGHFDSEKIKSKNDKIQYQFQELNRLAAEREKKLAEMKKLYE 3230
Query: 4869 LFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAAN 4690
R+I+D WI + AGS G D+ V+ L + ++ ++ + ++S++ + +
Sbjct: 3231 FVREIDDLQEWIEVQMTTAGSEEYGTDVEHVEQLTAQFESFVSNLNANESRLTACVAKGE 3290
Query: 4689 DMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSE 4510
++ +G+ I+ K + + W LK R+ L + Q H + A+E AW++E
Sbjct: 3291 ALLSEGNPNRDTIKAKRDETKQLWEELKDLVVARQEALAGARQVHVFDRTADETIAWVNE 3350
Query: 4509 KEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCK--YQEQPMG-Q 4339
K V S DYG D ++ ++L++ H A ++L A K +E + +A + Y + +
Sbjct: 3351 KISSVLSEDYGHDLETIQSLVRTHEAFEAELGAIKEQLESVVNEAQKLADTYPDAKEHIE 3410
Query: 4338 LGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIEP 4159
+ RD + ++ E R V K+ L A + E D ++ K P
Sbjct: 3411 VKRDETIEVWS--ELKDRTVQRKE----KLTQAEQLQAYFDEYRDLMAWINEMLAKITAP 3464
Query: 4158 GTAQQHAQQQVNSIGGKQ---SEIEDKY----QRLMMLGETRKRKLEEA---CKGYQLLR 4009
A+ A + ++ K +E++DK QR +L T ++LE + L+
Sbjct: 3465 DLAKDVAGAE--ALIDKHFLANEVQDKIAVLEQRKRLLDNTIVQRLEMYELNLDTQRFLK 3522
Query: 4008 EANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQI 3844
EA D+ WI SR+ + ++G + QVE L +K +DF+ + A E ++ + +I
Sbjct: 3523 EAEDMESWIISRQMQLKESKLGDSIAQVEDLLRKHEDFEKTVAAQEEKVLALKRI 3577
Score = 142 bits (358), Expect = 1e-31
Identities = 100/458 (21%), Positives = 209/458 (44%), Gaps = 11/458 (2%)
Frame = -1
Query: 2925 QEEKIKGLKLFAESLIK--NNHYDSPAVTRKRDQILDRWNGLKEAL----IQKRFKLGES 2764
+ +I+ L +L+K N + +P + + I W L+ A + R +L
Sbjct: 347 ERSEIEALYFHVNTLLKSLNQPHYTPQDGKMINDIEKAWQRLENAEHNREVALRDELLRQ 406
Query: 2763 QTLQQ----FSRDADEIENWMTEKFQIAQEENYRDPTN-IQQKHQKQQAFEAELHANSDR 2599
+ L+Q F + + E ++ E Q+ + Y + +K +A A++ A +DR
Sbjct: 407 EKLEQLNFKFEKKSVLREGYLNEMIQVLTDPRYGPALRQVDATVKKHEAISADILARADR 466
Query: 2598 IAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMA 2419
+ N L + G+ V R + +W L++ +L + + + +
Sbjct: 467 FNDLTDMCNELHQENY--HGKDRVKKRELEVITKWKELLELLENHKLKLSQMSSLMNLLR 524
Query: 2418 AVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLL 2239
+ + ++ SED G L VE LL+ HSLLE + + Q ++
Sbjct: 525 EIDATMTTIKALQAQFASEDVGPHLLGVEELLQAHSLLELQVTTLGETQRRYVRQGEAFK 584
Query: 2238 ENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKL 2059
D Q+ + +A Y+ + M+ RR +L +A + +QF D ++EE W+ +K+
Sbjct: 585 RGDYKDTSQLDAKLAELAKLYEELLAMSAARRARLDEARDFYQFVEDHENEEGWLVDKQR 644
Query: 2058 LVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIK 1879
+ + +DL V +L++KH+ ++ E+ +P+ + + G++L+ + ++
Sbjct: 645 ICKAGITAKDLRAVMSLQQKHKALEDEMKVRKPKSNQITEAGKKLI---VDKHSRMSDVQ 701
Query: 1878 KRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENM 1699
+++ L++ W + DL R ++L+++ + D E ++W+NEK ++ SD+FG +
Sbjct: 702 GKIDSLQEHWKALEDLVDLRKRQLEDAAEAYQYYADANEADSWLNEKMALVASDDFGVDE 761
Query: 1698 AGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNG 1585
Q LL++H Q +L + + +L + + LI G
Sbjct: 762 PSAQALLQRHRDLQGELNAYSGDILNLNQQAEKLIKAG 799
Score = 139 bits (349), Expect = 1e-30
Identities = 92/380 (24%), Positives = 186/380 (48%), Gaps = 1/380 (0%)
Frame = -1
Query: 2403 EFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQF 2224
E +L E+ +L YG L V+ +KKH + ADI+A DR ++ + + L + +
Sbjct: 424 EGYLNEMIQVLTDPRYGPALRQVDATVKKHEAISADILARADRFNDLTDMCNELHQENYH 483
Query: 2223 QGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSD 2044
++ +R + ++ + ++ + + KLS+ ++ R+ID + IK + +S+
Sbjct: 484 GKDRVKKRELEVITKWKELLELLENHKLKLSQMSSLMNLLREIDATMTTIKALQAQFASE 543
Query: 2043 DYGRDLPGVQNLRRKHRRIDTELAS-HEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRME 1867
D G L GV+ L + H ++ ++ + E Q V+ +GE R + Q+ ++
Sbjct: 544 DVGPHLLGVEELLQAHSLLELQVTTLGETQRRYVR-QGEAFKRGDYK---DTSQLDAKLA 599
Query: 1866 DLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQ 1687
+L + + ++ ++ R RLDE+ F F+ D E EE W+ +KQ+I + +++ V
Sbjct: 600 ELAKLYEELLAMSAARRARLDEARDFYQFVEDHENEEGWLVDKQRICKAGITAKDLRAVM 659
Query: 1686 GLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAE 1507
L +KH + ++++ K + + G LI + + ++ + D L+ +E + +
Sbjct: 660 SLQQKHKALEDEMKVRKPKSNQITEAGKKLIVDKHSRMSDVQGKIDSLQEHWKALEDLVD 719
Query: 1506 GRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLN 1327
R +L D + Q+ + +SW+ EK V S+DFG D S Q LL + LN
Sbjct: 720 LRKRQLEDAAEAYQYYADANEADSWLNEKMALVASDDFGVDEPSAQALLQRHRDLQGELN 779
Query: 1326 AFEHEGIQRITELKDQLVSS 1267
A+ + I + + ++L+ +
Sbjct: 780 AYSGD-ILNLNQQAEKLIKA 798
Score = 135 bits (341), Expect = 1e-29
Identities = 94/399 (23%), Positives = 180/399 (44%), Gaps = 15/399 (3%)
Frame = -1
Query: 7002 LQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXX 6823
+ A ++KHEA A++ A A +L N + Q N+ + +KKR E+ W
Sbjct: 446 VDATVKKHEAISADILARADRFNDLTDMCNELHQENYHGKDRVKKRELEVITKWKELLEL 505
Query: 6822 XXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKE 6643
+KL Q L++ +R+ D + I+ + +ED+G L VE L + L E
Sbjct: 506 LENHKLKLSQMSSLMNLLREIDATMTTIKALQAQFASEDVGPHLLGVEELLQAHS--LLE 563
Query: 6642 LGNHQYRINEINQAADKLVEEG-------HSEHDQIYKKRDDVNDAWHRLNTLAATRKEG 6484
L ++ + + + V +G + + Q+ K ++ + L ++A R+
Sbjct: 564 L-----QVTTLGETQRRYVRQGEAFKRGDYKDTSQLDAKLAELAKLYEELLAMSAARRAR 618
Query: 6483 LFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGK 6304
L A +F D + W+ +K + +DL V +LQ+KH+ E ++ + K
Sbjct: 619 LDEARDFYQFVEDHENEEGWLVDKQRICKAGITAKDLRAVMSLQQKHKALEDEMKVRKPK 678
Query: 6303 MLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADY 6124
Q+ + KL R + K D + W AL++ RK LE + + +++ AD
Sbjct: 679 SNQITEAGKKLIVDKHSRMSDVQGKIDSLQEHWKALEDLVDLRKRQLEDAAEAYQYYADA 738
Query: 6123 RDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEM 5944
+ SW+ + A++ +D+ D A+ALL+ H++ +GE++A + +KL++
Sbjct: 739 NEADSWLNEKMALVASDDFGVDEPSAQALLQRHRDLQGELNAYSGDILNLNQQAEKLIKA 798
Query: 5943 GI--------PESPEVQEKLEKLDHEKSSLLGLWEERRI 5851
GI PE + E+ E ++ + +WE+ +
Sbjct: 799 GICTLDLSAEPEPVQEMEQEEWVNETRLVPKEVWEDEPV 837
Score = 122 bits (305), Expect = 2e-25
Identities = 96/457 (21%), Positives = 186/457 (40%), Gaps = 19/457 (4%)
Frame = -1
Query: 4188 PAAYVKRIEPGTAQQHAQQQVNSIG--------GKQ-SEIEDKYQRLMMLGETRKRKLEE 4036
P Y +R E H + S+ GK ++IE +QRL R+ L +
Sbjct: 342 PPKYKERSEIEALYFHVNTLLKSLNQPHYTPQDGKMINDIEKAWQRLENAEHNREVALRD 401
Query: 4035 ACKGYQLLREANDLAE--------WIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLK 3880
+ L + N E ++ V G L QV+ KK + D+
Sbjct: 402 ELLRQEKLEQLNFKFEKKSVLREGYLNEMIQVLTDPRYGPALRQVDATVKKHEAISADIL 461
Query: 3879 ANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQ 3700
A R ++ + L R++++ ++ +W+ L +L +
Sbjct: 462 ARADRFNDLTDMCNELHQENY-HGKDRVKKRELEVITKWKELLELLENHKLKLSQMSSLM 520
Query: 3699 RFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKA 3520
R++D T I+ SED G L V+ L + H +E + LG+ + +
Sbjct: 521 NLLREIDATMTTIKALQAQFASEDVGPHLLGVEELLQAHSLLELQVTTLGETQRRYVRQG 580
Query: 3519 NRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIA 3340
++ + Q+ EL + + L + + R+ +L ++ D+ +F+ D+ + W+
Sbjct: 581 EAFKRGDYKDTSQLDAKLAELAKLYEELLAMSAARRARLDEARDFYQFVEDHENEEGWLV 640
Query: 3339 SMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDI 3160
++ + A D+ +L ++H+ E+ R + G +L+ H D+
Sbjct: 641 DKQRICKAGITAKDLRAVMSLQQKHKALEDEMKVRKPKSNQITEAGKKLIVDKHSRMSDV 700
Query: 3159 ENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGD 2980
+ ++ + E K LED R+ L+ E +Y D +AD+W++ + A +A +D D
Sbjct: 701 QGKIDSLQEHWKALEDLVDLRKRQLEDAAEAYQYYADANEADSWLNEKMALVASDDFGVD 760
Query: 2979 --NVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIK 2875
+ ++L+++H D +N I L AE LIK
Sbjct: 761 EPSAQALLQRHRDLQGELNAYSGDILNLNQQAEKLIK 797
Score = 121 bits (303), Expect = 3e-25
Identities = 106/502 (21%), Positives = 219/502 (43%), Gaps = 20/502 (3%)
Frame = -1
Query: 3360 DLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRT-----EIDSRAATFQAFDQFGNQ 3196
+L+ WI + + + N V G + L +EYRT + R+ +
Sbjct: 302 NLLSWIRAKTVELEKRNFPNSVEGIQGELLAFKEYRTVEKPPKYKERSEIEALYFHVNTL 361
Query: 3195 L--LNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNIL-DQCLELQLFYRDCEQADTWM 3025
L LN HY D + + +A + LE+A R L D+ L + + + +
Sbjct: 362 LKSLNQPHYTPQD-GKMINDIEKAWQRLENAEHNREVALRDELLRQEKLEQLNFKFEKKS 420
Query: 3024 SAREAFLAQE---------DPSGDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKN 2872
RE +L + P+ V++ +KKHE I + ++ L L +
Sbjct: 421 VLREGYLNEMIQVLTDPRYGPALRQVDATVKKHEAISADILARADRFNDLTDMCNELHQE 480
Query: 2871 NHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTE-KFQI 2695
N++ V ++ +++ +W L E L + KL + +L R+ D + + Q
Sbjct: 481 NYHGKDRVKKRELEVITKWKELLELLENHKLKLSQMSSLMNLLREIDATMTTIKALQAQF 540
Query: 2694 AQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGE--AAVSA 2521
A E+ +++ Q E ++ + ++ G E K G + + + A
Sbjct: 541 ASEDVGPHLLGVEELLQAHSLLELQVTTLGETQRRYVRQG----EAFKRGDYKDTSQLDA 596
Query: 2520 RLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLA 2341
+L L ++ L+ + + RL EA F+ ++ E WL + + + ++ KDL
Sbjct: 597 KLAELAKLYEELLAMSAARRARLDEARDFYQFVEDHENEEGWLVDKQRICKAGITAKDLR 656
Query: 2340 SVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKK 2161
+V +L +KH LE ++ + + ++ E L+ + + + + + + + ++
Sbjct: 657 AVMSLQQKHKALEDEMKVRKPKSNQITEAGKKLIVDKHSRMSDVQGKIDSLQEHWKALED 716
Query: 2160 MATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDT 1981
+ R+ +L A +Q++ D ++ +SW+ EK LV+SDD+G D P Q L ++HR +
Sbjct: 717 LVDLRKRQLEDAAEAYQYYADANEADSWLNEKMALVASDDFGVDEPSAQALLQRHRDLQG 776
Query: 1980 ELASHEPQVSLVKLKGEELLRS 1915
EL ++ + + + E+L+++
Sbjct: 777 ELNAYSGDILNLNQQAEKLIKA 798
Score = 117 bits (293), Expect = 4e-24
Identities = 90/403 (22%), Positives = 171/403 (42%), Gaps = 2/403 (0%)
Frame = -1
Query: 6798 QQALKLLHFIRQCDEILY--WIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQY 6625
Q+ L+ L+F + +L ++ E +T G L V+ +K + ++
Sbjct: 406 QEKLEQLNFKFEKKSVLREGYLNEMIQVLTDPRYGPALRQVDATVKKHEAISADILARAD 465
Query: 6624 RINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRD 6445
R N++ ++L +E + D++ K+ +V W L L K L + R+
Sbjct: 466 RFNDLTDMCNELHQENYHGKDRVKKRELEVITKWKELLELLENHKLKLSQMSSLMNLLRE 525
Query: 6444 ADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAE 6265
D T+ I +S+D G L V+ L + H E + L + ++
Sbjct: 526 IDATMTTIKALQAQFASEDVGPHLLGVEELLQAHSLLELQVTTLGETQRRYVRQGEAFKR 585
Query: 6264 THPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAV 6085
+ K + + L + R+ L+ + ++F+ D+ + W+ D + +
Sbjct: 586 GDYKDTSQLDAKLAELAKLYEELLAMSAARRARLDEARDFYQFVEDHENEEGWLVDKQRI 645
Query: 6084 IGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLE 5905
A AKD+ +L + H+ + E+ R NQ AG+KL+ +VQ K++
Sbjct: 646 CKAGITAKDLRAVMSLQQKHKALEDEMKVRKPKSNQITEAGKKLIVDKHSRMSDVQGKID 705
Query: 5904 KLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVE 5725
L +L L + R+ E + +Y D +A++W+N++ A +A+ D G S +
Sbjct: 706 SLQEHWKALEDLVDLRKRQLEDAAEAYQYYADANEADSWLNEKMALVASDDFGVDEPSAQ 765
Query: 5724 HLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAE 5596
L+++H D + L A I L++ A KLI+ D AE
Sbjct: 766 ALLQRHRDLQGELNAYSGDILNLNQQAEKLIKAGICTLDLSAE 808
Score = 103 bits (258), Expect = 5e-20
Identities = 74/310 (23%), Positives = 135/310 (42%), Gaps = 1/310 (0%)
Frame = -1
Query: 7197 DDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILE-KLQTAQEEN 7021
D + +R EV+ + + + + +L + R+ D I + Q A E+
Sbjct: 486 DRVKKRELEVITKWKELLELLENHKLKLSQMSSLMNLLREIDATMTTIKALQAQFASEDV 545
Query: 7020 FRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALW 6841
++ +Q H E +V +T + G A + ++ + + +L EL L+
Sbjct: 546 GPHLLGVEELLQAHSLLELQVTTLGETQRRYVRQGEAFKRGDYKDTSQLDAKLAELAKLY 605
Query: 6840 XXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKF 6661
+ +L +A F+ + W+ +K+ A DL V LQ+K
Sbjct: 606 EELLAMSAARRARLDEARDFYQFVEDHENEEGWLVDKQRICKAGITAKDLRAVMSLQQKH 665
Query: 6660 DDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGL 6481
E+ + + N+I +A KL+ + HS + K D + + W L L RK L
Sbjct: 666 KALEDEMKVRKPKSNQITEAGKKLIVDKHSRMSDVQGKIDSLQEHWKALEDLVDLRKRQL 725
Query: 6480 FGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKM 6301
A + ++ DA+E +W+ EK ++SDD+G D + QAL ++H + +L A G +
Sbjct: 726 EDAAEAYQYYADANEADSWLNEKMALVASDDFGVDEPSAQALLQRHRDLQGELNAYSGDI 785
Query: 6300 LQLEKEAHKL 6271
L L ++A KL
Sbjct: 786 LNLNQQAEKL 795
Score = 93.6 bits (231), Expect = 6e-17
Identities = 111/511 (21%), Positives = 204/511 (39%), Gaps = 62/511 (12%)
Frame = -1
Query: 4857 IEDELAWIREKEQVAGSTNRGRDLIGVQN--LIKKQQALIAEIANHD--SQIESVSSAAN 4690
I + L+WIR K N + G+Q L K+ + + + S+IE++ N
Sbjct: 300 ITNLLSWIRAKTVELEKRNFPNSVEGIQGELLAFKEYRTVEKPPKYKERSEIEALYFHVN 359
Query: 4689 DMIQ---QGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEA--- 4528
+++ Q H+ P+ + + W+ L++ R L D L + L N
Sbjct: 360 TLLKSLNQPHY-TPQDGKMINDIEKAWQRLENAEHNREVALRDELLRQEKLEQLNFKFEK 418
Query: 4527 -----DAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCK 4363
+ +++E ++ YG +A +KKH A+ +D+ A DL ++
Sbjct: 419 KSVLREGYLNEMIQVLTDPRYGPALRQVDATVKKHEAISADILARADRFNDLTDMCNEL- 477
Query: 4362 YQEQPMGQLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKV--------EVN 4207
+QE G+ D +K EV K ++L LL ++ E++
Sbjct: 478 HQENYHGK----------DRVKKRELEVITKWKELLELLENHKLKLSQMSSLMNLLREID 527
Query: 4206 DRQGFVPAAYVKRIEPGTA----------QQHA--QQQVNSIGGKQ-------------- 4105
+ A + Q H+ + QV ++G Q
Sbjct: 528 ATMTTIKALQAQFASEDVGPHLLGVEELLQAHSLLELQVTTLGETQRRYVRQGEAFKRGD 587
Query: 4104 -----------SEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAA 3958
+E+ Y+ L+ + R+ +L+EA YQ + + + W+ ++ +
Sbjct: 588 YKDTSQLDAKLAELAKLYEELLAMSAARRARLDEARDFYQFVEDHENEEGWLVDKQRICK 647
Query: 3957 QQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATA--LTSVGQTETAVRIRQQI 3784
DL V LQ+K + ++K VR + NQI A V + ++ +I
Sbjct: 648 AGITAKDLRAVMSLQQKHKALEDEMK---VRKPKSNQITEAGKKLIVDKHSRMSDVQGKI 704
Query: 3783 EDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSV 3604
+ L W+AL QL A E +++ D +E W+ EK + S+DFG D S
Sbjct: 705 DSLQEHWKALEDLVDLRKRQLEDAAEAYQYYADANEADSWLNEKMALVASDDFGVDEPSA 764
Query: 3603 QALQRKHEGVERDLAALGDKIKSLDEKANRL 3511
QAL ++H ++ +L A I +L+++A +L
Sbjct: 765 QALLQRHRDLQGELNAYSGDILNLNQQAEKL 795
Score = 53.9 bits (128), Expect = 6e-05
Identities = 99/461 (21%), Positives = 180/461 (38%), Gaps = 26/461 (5%)
Frame = -1
Query: 1755 AWMNEKQQILGSDNFGENMAGVQGLL---KKHDTFQVDLEL-HKQRVADLINKGDTLIHN 1588
+W+ K L NF ++ G+QG L K++ T + + + + L +TL+ +
Sbjct: 305 SWIRAKTVELEKRNFPNSVEGIQGELLAFKEYRTVEKPPKYKERSEIEALYFHVNTLLKS 364
Query: 1587 GN--HHAPHIKQRCDQLRARLIEIESMAEGRLAKLRD--------NSAYLQFMWKCDVVE 1438
N H+ P + + + +E+ R LRD +F K + E
Sbjct: 365 LNQPHYTPQDGKMINDIEKAWQRLENAEHNREVALRDELLRQEKLEQLNFKFEKKSVLRE 424
Query: 1437 SWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQ 1258
++ E Q + +G L V + K EA A + A + +T++ ++L +
Sbjct: 425 GYLNEMIQVLTDPRYGPALRQVDATVKKHEAISADILA-RADRFNDLTDMCNELHQENYH 483
Query: 1257 QSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFEN 1078
++KR VI +W+ LL E + + E+ A + F
Sbjct: 484 GKDRVKKRELEVITKWKELLELLENHKLKLSQMSSLMNLLREID-ATMTTIKALQAQF-- 540
Query: 1077 AEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTW 898
A ED+ L + L AH + +++ E R+ R+ ++F G T
Sbjct: 541 ASEDVGP-----HLLGVEELLQAHSLLELQVTTLGETQRRYV---RQGEAFKRGDYKDT- 591
Query: 897 FTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLR--REFAKLANAFHAWLTNTRQE 724
+DA L + K E+ LA R+ D+ R +F + WL + +Q
Sbjct: 592 SQLDA------KLAELAKLYEELLAMSAARRARLDEARDFYQFVEDHENEEGWLVD-KQR 644
Query: 723 MMEAGGTLEE--QLDAVERKAK----EIKANKGQLRQIEEKGAMLERNLILDNRYTEHST 562
+ +AG T ++ + ++++K K E+K K + QI E G + LI+D
Sbjct: 645 ICKAGITAKDLRAVMSLQQKHKALEDEMKVRKPKSNQITEAG----KKLIVDKHSRMSDV 700
Query: 561 VG----IAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEA 451
G + + W L+ L + LE +A + EA
Sbjct: 701 QGKIDSLQEHWKALEDLVDLRKRQLEDAAEAYQYYADANEA 741
>gi|161334|gb|AAA30008.1| alpha-spectrin
Length = 682
Score = 759 bits (1959), Expect = 0.0
Identities = 386/678 (56%), Positives = 497/678 (72%), Gaps = 6/678 (0%)
Frame = -1
Query: 4719 QIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSD 4540
+I+ V+ M+ +GHF EI K+ L + W+ LK K+ +R+ DL+DSL+A QY +D
Sbjct: 5 RIKMVTKTGEQMLDEGHFANDEISAKVKGLEEKWKNLKDKSSQRKDDLEDSLEAQQYFAD 64
Query: 4539 ANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKY 4360
ANEA++WM EKEPIV S DYGKDEDSAE+ LKKH+ L++DL A++ TIE L+KQA C+
Sbjct: 65 ANEAESWMQEKEPIVASEDYGKDEDSAESQLKKHKTLMADLVAYRTTIEMLKKQAEGCRQ 124
Query: 4359 QEQPMGQ-LGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPA 4183
Q+ P+ + +G++ V+ALYDY EKSPREVSMKKGDVL LLN+SN+DWWKVEVNDRQGFVPA
Sbjct: 125 QDIPISEDVGKEYVVALYDYMEKSPREVSMKKGDVLVLLNSSNKDWWKVEVNDRQGFVPA 184
Query: 4182 AYVKRIEPG-TAQQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLRE 4006
AYVK+++ +A Q + +I +Q IE +YQ L+ RK LEE+ K + L+RE
Sbjct: 185 AYVKKMDAAQSASQANLVEDANIMRRQENIEQEYQALLDKAGVRKEALEESVKRHSLVRE 244
Query: 4005 ANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTS 3826
ANDL +W+ + AV E+G DLEQVEVLQKKFDDF+ DLKANE RL E+N I L
Sbjct: 245 ANDLIQWVNDKAAVVESAEVGDDLEQVEVLQKKFDDFQKDLKANESRLLEINTILETLDL 304
Query: 3825 VGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDD 3646
E + + Q++ DLN W+AL L +AHEVQRF RD DET+DWI +K+
Sbjct: 305 EKVPELTL-LSQKVNDLNTEWQALQKLTDDRSASLATAHEVQRFFRDADETKDWIDDKNK 363
Query: 3645 ALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQ 3466
AL++E+FG DL SVQALQRKH+G+ERDL ALG ++++LDE A+RL Q+HP+ AE I +
Sbjct: 364 ALNTENFGHDLHSVQALQRKHQGLERDLNALGKQVQTLDETADRLVQTHPDQAEPIVAKR 423
Query: 3465 RELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGA 3286
E++E W+ L +AN RK KL+DSYD QRFLSD+RDLM W M LV+S ELA DVTGA
Sbjct: 424 AEIDEAWHTLQDRANARKAKLMDSYDLQRFLSDFRDLMSWTNGMKTLVASDELAKDVTGA 483
Query: 3285 EALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAG-DIENRLQGVNEAR-KGLED 3112
EALLERHQE TE++ RA TFQAF+ FG +L+ + HYAA +++ +L + + R K LE
Sbjct: 484 EALLERHQELHTEMEPRAGTFQAFEAFGQELIKNDHYAASPEVQEKLDILGKRREKDLEV 543
Query: 3111 AWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQE--DPSGDNVESLIKKHEDFDK 2938
+W RR+ LDQCLELQLF RDCEQA+ WM AREAFLA E S D+VESLIKKHEDFDK
Sbjct: 544 SWNDRRHKLDQCLELQLFLRDCEQAEAWMGAREAFLASEGLTDSLDSVESLIKKHEDFDK 603
Query: 2937 AINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQT 2758
A++ QE+KI ++ F + LI N+HYD PA+ KRDQ+L+RW+ LK ALI+KR KLGES T
Sbjct: 604 ALSLQEQKINAIESFPQQLINNDHYDGPAIGTKRDQVLERWHSLKAALIEKRSKLGESHT 663
Query: 2757 LQQFSRDADEIENWMTEK 2704
LQQFSRDADE+E W++EK
Sbjct: 664 LQQFSRDADEVEAWISEK 681
Score = 377 bits (969), Expect = e-102
Identities = 205/485 (42%), Positives = 297/485 (60%), Gaps = 2/485 (0%)
Frame = -1
Query: 6903 QHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKET 6724
Q N +I +R E + + + L++++K +R+ ++++ W+ +K
Sbjct: 198 QANLVEDANIMRRQENIEQEYQALLDKAGVRKEALEESVKRHSLVREANDLIQWVNDKAA 257
Query: 6723 YVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKR 6544
V + ++G DLE VE+LQ+KFDDF K+L ++ R+ EIN + L E E + +K
Sbjct: 258 VVESAEVGDDLEQVEVLQKKFDDFQKDLKANESRLLEINTILETLDLEKVPELTLLSQKV 317
Query: 6543 DDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNV 6364
+D+N W L L R L AH+VQRF RDADET WI +K+ AL+++++G DL++V
Sbjct: 318 NDLNTEWQALQKLTDDRSASLATAHEVQRFFRDADETKDWIDDKNKALNTENFGHDLHSV 377
Query: 6363 QALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKA 6184
QALQRKH+G ERDL AL ++ L++ A +L +THPD+AE I K + AW+ L+++A
Sbjct: 378 QALQRKHQGLERDLNALGKQVQTLDETADRLVQTHPDQAEPIVAKRAEIDEAWHTLQDRA 437
Query: 6183 QHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEI 6004
RK L S+ L RFL+D+RDL+SW MK ++ +DELAKDV GAEALLE HQE E+
Sbjct: 438 NARKAKLMDSYDLQRFLSDFRDLMSWTNGMKTLVASDELAKDVTGAEALLERHQELHTEM 497
Query: 6003 DARADSFNQTASAGQKLVEMG-IPESPEVQEKLEKLDHEKSSLLGL-WEERRILYEQCMD 5830
+ RA +F + GQ+L++ SPEVQEKL+ L + L + W +RR +QC++
Sbjct: 498 EPRAGTFQAFEAFGQELIKNDHYAASPEVQEKLDILGKRREKDLEVSWNDRRHKLDQCLE 557
Query: 5829 LQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDE 5650
LQLF RD EQAE WM +EAFLA+ L DSLDSVE LIKKHEDF+K+L+ QE+KINA++
Sbjct: 558 LQLFLRDCEQAEAWMGAREAFLASEGLTDSLDSVESLIKKHEDFDKALSLQEQKINAIES 617
Query: 5649 FATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSW 5470
F +LI HY + + + L ES+ Q F RD DE+ +W
Sbjct: 618 FPQQLINNDHYDGPAIGTKRDQVLERWHSLKAALIEKRSKLGESHTLQQFSRDADEVEAW 677
Query: 5469 ITEKL 5455
I+EK+
Sbjct: 678 ISEKI 682
Score = 225 bits (574), Expect = 1e-56
Identities = 171/723 (23%), Positives = 331/723 (45%), Gaps = 14/723 (1%)
Frame = -1
Query: 3546 KIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSD 3367
+IK + + ++ A ++I + L E+W L K++ RK+ L DS + Q++ +D
Sbjct: 5 RIKMVTKTGEQMLDEGHFANDEISAKVKGLEEKWKNLKDKSSQRKDDLEDSLEAQQYFAD 64
Query: 3366 YRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLN 3187
+ W+ +V+S++ D AE+ L++H+ ++ + T + +
Sbjct: 65 ANEAESWMQEKEPIVASEDYGKDEDSAESQLKKHKTLMADLVAYRTTIEMLKKQAEGC-- 122
Query: 3186 SHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAF 3007
R Q + + ++ VA + +++ S RE
Sbjct: 123 -----------RQQDIPISEDVGKEYVVALYDYMEK------------------SPREVS 153
Query: 3006 LAQEDPSGDNVESLIKKHEDFDKA-INTQEEKIKGLKL----FAESLIKNNHYDSPAVTR 2842
+ + GD + L ++D+ K +N ++ + + A+S + N + + R
Sbjct: 154 MKK----GDVLVLLNSSNKDWWKVEVNDRQGFVPAAYVKKMDAAQSASQANLVEDANIMR 209
Query: 2841 KRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTN 2662
+++ I + L + ++ L ES R+A+++ W+ +K + + D
Sbjct: 210 RQENIEQEYQALLDKAGVRKEALEESVKRHSLVREANDLIQWVNDKAAVVESAEVGDDLE 269
Query: 2661 -IQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGE--AAVSARLKALNDQWD 2491
++ +K F+ +L AN R+ I N ++E +S ++ LN +W
Sbjct: 270 QVEVLQKKFDDFQKDLKANESRLLEI----NTILETLDLEKVPELTLLSQKVNDLNTEWQ 325
Query: 2490 LLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHS 2311
L K T ++S L A++ + F + + W+ + L +E++G DL SV+ L +KH
Sbjct: 326 ALQKLTDDRSASLATAHEVQRFFRDADETKDWIDDKNKALNTENFGHDLHSVQALQRKHQ 385
Query: 2310 LLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLS 2131
LE D+ A +V ++E AD L++ Q + I +R I + + ++ A R+ KL
Sbjct: 386 GLERDLNALGKQVQTLDETADRLVQTHPDQAEPIVAKRAEIDEAWHTLQDRANARKAKLM 445
Query: 2130 KALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVS 1951
+ ++ +F D D SW K LV+SD+ +D+ G + L +H+ + TE+
Sbjct: 446 DSYDLQRFLSDFRDLMSWTNGMKTLVASDELAKDVTGAEALLERHQELHTEMEPRAGTFQ 505
Query: 1950 LVKLKGEELLRSAAEAGVGEDQI------KKRMEDLEQSWGQIRDLTGNRHQRLDESEAF 1789
+ G+EL+++ A E Q K+R +DLE SW +R +LD+
Sbjct: 506 AFEAFGQELIKNDHYAASPEVQEKLDILGKRREKDLEVSW-------NDRRHKLDQCLEL 558
Query: 1788 QAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINK 1609
Q FL D E+ EAWM ++ L S+ +++ V+ L+KKH+ F L L +Q++ + +
Sbjct: 559 QLFLRDCEQAEAWMGAREAFLASEGLTDSLDSVESLIKKHEDFDKALSLQEQKINAIESF 618
Query: 1608 GDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWI 1429
LI+N ++ P I + DQ+ R +++ + +KL ++ QF D VE+WI
Sbjct: 619 PQQLINNDHYDGPAIGTKRDQVLERWHSLKAALIEKRSKLGESHTLQQFSRDADEVEAWI 678
Query: 1428 AEK 1420
+EK
Sbjct: 679 SEK 681
Score = 218 bits (555), Expect = 2e-54
Identities = 157/709 (22%), Positives = 324/709 (45%), Gaps = 3/709 (0%)
Frame = -1
Query: 6624 RINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRD 6445
RI + + +++++EGH +D+I K + + W L ++ RK+ L + + Q++ D
Sbjct: 5 RIKMVTKTGEQMLDEGHFANDEISAKVKGLEEKWKNLKDKSSQRKDDLEDSLEAQQYFAD 64
Query: 6444 ADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAE 6265
A+E +W+ EK+ ++S+DYG+D ++ ++ +KH+ DL A + L+K+A
Sbjct: 65 ANEAESWMQEKEPIVASEDYGKDEDSAESQLKKHKTLMADLVAYRTTIEMLKKQAEGC-- 122
Query: 6264 THPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAV 6085
+ D + + KE D +E+S R++ GD+ +
Sbjct: 123 -----------RQQDIPISEDVGKEYVVALYDYMEKS---------PREVSMKKGDVLVL 162
Query: 6084 IGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLE 5905
+ + KD E + +G + A ++ + A Q + + E + + E
Sbjct: 163 LNSSN--KDWWKVEV-----NDRQGFVPA---AYVKKMDAAQSASQANLVEDANIMRRQE 212
Query: 5904 KLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVE 5725
++ E +LL R+ E+ + R+ W+N + A + + ++GD L+ VE
Sbjct: 213 NIEQEYQALLDKAGVRKEALEESVKRHSLVREANDLIQWVNDKAAVVESAEVGDDLEQVE 272
Query: 5724 HLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXX 5545
L KK +DF+K L A E ++ ++ L + +++
Sbjct: 273 VLQKKFDDFQKDLKANESRLLEINTILETLDLEKVPELTLLSQKVNDLNTEWQALQKLTD 332
Query: 5544 XRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSY-LDPTNIRGKLQKHINFEQELK 5368
R +L +++ Q F RD DE WI +K +++ D +++ +KH E++L
Sbjct: 333 DRSASLATAHEVQRFFRDADETKDWIDDKNKALNTENFGHDLHSVQALQRKHQGLERDLN 392
Query: 5367 ANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQ 5188
A ++ + T ++++ + A+ I + +++ W+ L D N + AKL ++ + Q+
Sbjct: 393 ALGKQVQTLDETADRLVQTHPDQAEPIVAKRAEIDEAWHTLQDRANARKAKLMDSYDLQR 452
Query: 5187 FNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQ 5008
F + D+ +W + ++ VAS++ KD+ + L ++ + ++ + Q
Sbjct: 453 FLSDFRDLMSWTNGMKTLVASDELAKDVTGAEALLERHQELHTEMEPRAGTFQAFEAFGQ 512
Query: 5007 QFQEEEHFNAPVIVRKQENL--QQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWI 4834
+ + +H+ A V+++ ++ ++R L R+ KL + + RD E AW+
Sbjct: 513 ELIKNDHYAASPEVQEKLDILGKRREKDLEVSWNDRRHKLDQCLELQLFLRDCEQAEAWM 572
Query: 4833 REKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPE 4654
+E S L V++LIKK + ++ + +I ++ S +I H+ P
Sbjct: 573 GAREAFLASEGLTDSLDSVESLIKKHEDFDKALSLQEQKINAIESFPQQLINNDHYDGPA 632
Query: 4653 IRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEK 4507
I K Q+ + W LK+ ++R+ L +S Q+ DA+E +AW+SEK
Sbjct: 633 IGTKRDQVLERWHSLKAALIEKRSKLGESHTLQQFSRDADEVEAWISEK 681
Score = 213 bits (542), Expect = 6e-53
Identities = 165/714 (23%), Positives = 311/714 (43%), Gaps = 9/714 (1%)
Frame = -1
Query: 6939 IANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQC 6760
I + KTG M+ HFA++ I +++ L W + L+ +L+ +
Sbjct: 6 IKMVTKTGEQMLDEGHFANDEISAKVKGLEEKWKNLKDKSSQRKDDLEDSLEAQQYFADA 65
Query: 6759 DEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEE 6580
+E W++EKE V +ED G D + E +K + +L ++ I + + A+ ++
Sbjct: 66 NEAESWMQEKEPIVASEDYGKDEDSAESQLKKHKTLMADLVAYRTTIEMLKKQAEGCRQQ 125
Query: 6579 GHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLAL 6400
+ + K+ + + + K+G + L +
Sbjct: 126 DIPISEDVGKEYVVALYDYMEKSPREVSMKKG---------------DVLVLLNSS---- 166
Query: 6399 SSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDD 6220
+ D + ++N+ Q + D AA L ++A+ I ++ ++
Sbjct: 167 NKDWWKVEVNDRQGFVPAAYVKKMD-AAQSASQANLVEDAN------------IMRRQEN 213
Query: 6219 TKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEA 6040
+ + AL +KA RK+ LE S + H + + DLI W+ D AV+ + E+ D+ E
Sbjct: 214 IEQEYQALLDKAGVRKEALEESVKRHSLVREANDLIQWVNDKAAVVESAEVGDDLEQVEV 273
Query: 6039 LLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEE 5860
L + + + ++ A + + + L +PE + +K+ L+ E +L L ++
Sbjct: 274 LQKKFDDFQKDLKANESRLLEINTILETLDLEKVPELTLLSQKVNDLNTEWQALQKLTDD 333
Query: 5859 RRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAA 5680
R ++Q F+RD ++ + W++ + L + G L SV+ L +KH+ E+ L A
Sbjct: 334 RSASLATAHEVQRFFRDADETKDWIDDKNKALNTENFGHDLHSVQALQRKHQGLERDLNA 393
Query: 5679 QEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTF 5500
+++ LDE A +L+Q A+ + R L +SY Q F
Sbjct: 394 LGKQVQTLDETADRLVQTHPDQAEPIVAKRAEIDEAWHTLQDRANARKAKLMDSYDLQRF 453
Query: 5499 DRDCDEMVSWIT-EKLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQ 5323
D +++SW K A D+ D T L++H E++ + G++
Sbjct: 454 LSDFRDLMSWTNGMKTLVASDELAKDVTGAEALLERHQELHTEMEPRAGTFQAFEAFGQE 513
Query: 5322 IIDSGHFAA--------DHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIED 5167
+I + H+AA D +G R + +L + N + KL + Q F R+ E
Sbjct: 514 LIKNDHYAASPEVQEKLDILGKRREK------DLEVSWNDRRHKLDQCLELQLFLRDCEQ 567
Query: 5166 VEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEH 4987
EAW+ E +ASE L SV++L KK + + +++ I+ QQ +H
Sbjct: 568 AEAWMGAREAFLASEGLTDSLDSVESLIKKHEDFDKALSLQEQKINAIESFPQQLINNDH 627
Query: 4986 FNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREK 4825
++ P I K++ + +R+++L+ L +++ KLGESH Q RD ++ AWI EK
Sbjct: 628 YDGPAIGTKRDQVLERWHSLKAALIEKRSKLGESHTLQQFSRDADEVEAWISEK 681
Score = 193 bits (490), Expect = 6e-47
Identities = 166/688 (24%), Positives = 295/688 (42%), Gaps = 13/688 (1%)
Frame = -1
Query: 6237 HQKNDDTKAA-------WNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIG 6079
H ND+ A W LK+K+ RKD LE S + ++ AD + SW+ + + ++
Sbjct: 21 HFANDEISAKVKGLEEKWKNLKDKSSQRKDDLEDSLEAQQYFADANEAESWMQEKEPIVA 80
Query: 6078 ADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKL 5899
+++ KD AE+ L+ H+ ++ A + + + IP S +V
Sbjct: 81 SEDYGKDEDSAESQLKKHKTLMADLVAYRTTIEMLKKQAEGCRQQDIPISEDVG------ 134
Query: 5898 DHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHL 5719
K ++ L++ Y + E M K + + VE
Sbjct: 135 ---KEYVVALYD---------------YMEKSPREVSMKKGDVLVLLNSSNKDWWKVE-- 174
Query: 5718 IKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXR 5539
+ + F AA +K++A A Q ++ R
Sbjct: 175 VNDRQGFVP--AAYVKKMDA----AQSASQANLVEDANIMRRQENIEQEYQALLDKAGVR 228
Query: 5538 GNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGKLQKHIN-FEQELKAN 5362
AL+ES KR + R+ ++++ W+ +K + D LQK + F+++LKAN
Sbjct: 229 KEALEESVKRHSLVREANDLIQWVNDKAAVVESAEVGDDLEQVEVLQKKFDDFQKDLKAN 288
Query: 5361 ENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFN 5182
E+RL +I + E + + ++ +N W L T+ + A L A Q+F
Sbjct: 289 ESRLLEINTILETLDLEKVPELTLLSQKVNDLNTEWQALQKLTDDRSASLATAHEVQRFF 348
Query: 5181 RNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQF 5002
R+ ++ + W+ + + +E++G DL SVQ LQ+K +E D NA +V + + A +
Sbjct: 349 RDADETKDWIDDKNKALNTENFGHDLHSVQALQRKHQGLERDLNALGKQVQTLDETADRL 408
Query: 5001 QEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKE 4822
+ A IV K+ + + ++ L+D RK KL +S+ + D D ++W +
Sbjct: 409 VQTHPDQAEPIVAKRAEIDEAWHTLQDRANARKAKLMDSYDLQRFLSDFRDLMSWTNGMK 468
Query: 4821 QVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLA-PEIRD 4645
+ S +D+ G + L+++ Q L E+ ++ + ++I+ H+ A PE+++
Sbjct: 469 TLVASDELAKDVTGAEALLERHQELHTEMEPRAGTFQAFEAFGQELIKNDHYAASPEVQE 528
Query: 4644 KLAQL-RDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDE 4468
KL L + + L+ RR LD L+ +L D +A+AWM +E + S
Sbjct: 529 KLDILGKRREKDLEVSWNDRRHKLDQCLELQLFLRDCEQAEAWMGAREAFLASEGLTDSL 588
Query: 4467 DSAEALLKKHR---ALLSDLEAFKGTIEDLRKQASQCKYQEQPMGQLGRDCVLALYDYQE 4297
DS E+L+KKH LS E IE +Q + + P RD VL + +
Sbjct: 589 DSVESLIKKHEDFDKALSLQEQKINAIESFPQQLINNDHYDGPAIGTKRDQVLERWHSLK 648
Query: 4296 KSPREVSMKKGDVLTLLNASNRDWWKVE 4213
+ E K G+ TL S RD +VE
Sbjct: 649 AALIEKRSKLGESHTLQQFS-RDADEVE 675
Score = 171 bits (433), Expect = 2e-40
Identities = 159/727 (21%), Positives = 312/727 (42%), Gaps = 5/727 (0%)
Frame = -1
Query: 2601 RIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFM 2422
RI + + G +++ E +SA++K L ++W L ++++ L+++ + + +
Sbjct: 5 RIKMVTKTGEQMLDEGHFANDE--ISAKVKGLEEKWKNLKDKSSQRKDDLEDSLEAQQYF 62
Query: 2421 AAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSL 2242
A + E W+ E E ++ SEDYGKD S E+ LKKH L AD+VA++ + + +QA+
Sbjct: 63 ADANEAESWMQEKEPIVASEDYGKDEDSAESQLKKHKTLMADLVAYRTTIEMLKKQAEGC 122
Query: 2241 LENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKK 2062
+ D + + ++ + YD ++K E +K+
Sbjct: 123 RQQDIPISEDVG--KEYVVALYDYMEK----------------------SPREVSMKKGD 158
Query: 2061 LLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGED-Q 1885
+LV + +D V E+ + V +K + +SA++A + ED
Sbjct: 159 VLVLLNSSNKDWWKV------------EVNDRQGFVPAAYVKKMDAAQSASQANLVEDAN 206
Query: 1884 IKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGE 1705
I +R E++EQ + + D G R + L+ES + + + + W+N+K ++ S G+
Sbjct: 207 IMRRQENIEQEYQALLDKAGVRKEALEESVKRHSLVREANDLIQWVNDKAAVVESAEVGD 266
Query: 1704 NMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIE 1525
++ V+ L KK D FQ DL+ ++ R+ ++ +TL + Q+ + L
Sbjct: 267 DLEQVEVLQKKFDDFQKDLKANESRLLEINTILETLDLEKVPELTLLSQKVNDLNTEWQA 326
Query: 1524 IESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEA 1345
++ + + R A L +F D + WI +K + + +E+FG DL SVQ L K +
Sbjct: 327 LQKLTDDRSASLATAHEVQRFFRDADETKDWIDDKNKALNTENFGHDLHSVQALQRKHQG 386
Query: 1344 FDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXX 1165
+ LNA + +Q + E D+LV + Q+ I + + + W L + AR+
Sbjct: 387 LERDLNALGKQ-VQTLDETADRLVQTHPDQAEPIVAKRAEIDEAWHTLQDRANARKAKLM 445
Query: 1164 XXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSL 985
+ + SW + + + AL + H E +
Sbjct: 446 DSYDLQRFLSDF--------RDLMSWTNGMKTLVASDELAKDVTGAEALLERHQELHTEM 497
Query: 984 SSAEEDFRQLQDLDRR-IKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQR 808
F+ + + IK+ + +P +D L +E++ E++ +R
Sbjct: 498 EPRAGTFQAFEAFGQELIKNDHYAASPEVQEKLDILGKR--------REKDLEVSWNDRR 549
Query: 807 QEENDKLRRE-FAKLANAFHAWLTNTRQEMMEAGGTLEEQLDAVERKAKEIKANKGQLRQ 631
+ + L + F + AW+ R+ + + G L + LD+VE K+ + L
Sbjct: 550 HKLDQCLELQLFLRDCEQAEAWM-GAREAFLASEG-LTDSLDSVESLIKKHEDFDKALSL 607
Query: 630 IEEKGAMLER--NLILDNRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSE 457
E+K +E +++N + + +G + DQ+ R I+ R++ G S
Sbjct: 608 QEQKINAIESFPQQLINNDHYDGPAIGTKR-----DQVLERWHSLKAALIEKRSKLGES- 661
Query: 456 EALREFS 436
L++FS
Sbjct: 662 HTLQQFS 668
Score = 168 bits (425), Expect = 2e-39
Identities = 158/729 (21%), Positives = 312/729 (42%), Gaps = 3/729 (0%)
Frame = -1
Query: 2916 KIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRD 2737
+IK + E ++ H+ + ++ K + ++W LK+ Q++ L +S QQ+ D
Sbjct: 5 RIKMVTKTGEQMLDEGHFANDEISAKVKGLEEKWKNLKDKSSQRKDDLEDSLEAQQYFAD 64
Query: 2736 ADEIENWMTEKFQIAQEENY-RDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIE 2560
A+E E+WM EK I E+Y +D + + + +K + A+L A I + +
Sbjct: 65 ANEAESWMQEKEPIVASEDYGKDEDSAESQLKKHKTLMADLVAYRTTIEMLKKQAEG--- 121
Query: 2559 NAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVE 2380
C + +S + + ++ + + EKS R E + +K G+V
Sbjct: 122 ---CRQQDIPIS---EDVGKEYVVALYDYMEKSPR--EVSMKK-------------GDVL 160
Query: 2379 ILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAER 2200
+LL S + KD VE + + + A V D A S + + + I R
Sbjct: 161 VLLNSSN--KDWWKVE-VNDRQGFVPAAYVKKMDA-------AQSASQANLVEDANIMRR 210
Query: 2199 RKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPG 2020
++ I Y + A R++ L +++ H R+ +D W+ +K +V S + G DL
Sbjct: 211 QENIEQEYQALLDKAGVRKEALEESVKRHSLVREANDLIQWVNDKAAVVESAEVGDDLEQ 270
Query: 2019 VQNLRRKHRRIDTELASHEPQVSLVKLKGEEL-LRSAAEAGVGEDQIKKRMEDLEQSWGQ 1843
V+ L++K +L ++E ++ + E L L E + + +++ DL W
Sbjct: 271 VEVLQKKFDDFQKDLKANESRLLEINTILETLDLEKVPELTL----LSQKVNDLNTEWQA 326
Query: 1842 IRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDT 1663
++ LT +R L + Q F D +E + W+++K + L ++NFG ++ VQ L +KH
Sbjct: 327 LQKLTDDRSASLATAHEVQRFFRDADETKDWIDDKNKALNTENFGHDLHSVQALQRKHQG 386
Query: 1662 FQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRD 1483
+ DL ++V L D L+ A I + ++ ++ A R AKL D
Sbjct: 387 LERDLNALGKQVQTLDETADRLVQTHPDQAEPIVAKRAEIDEAWHTLQDRANARKAKLMD 446
Query: 1482 NSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQ 1303
+ +F+ + SW + V S++ +D++ + LL + + + Q
Sbjct: 447 SYDLQRFLSDFRDLMSWTNGMKTLVASDELAKDVTGAEALLERHQELHTEMEP-RAGTFQ 505
Query: 1302 RITELKDQLVSSEH-QQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELY 1126
+L+ ++H SP ++++ + +R + L S R EL
Sbjct: 506 AFEAFGQELIKNDHYAASPEVQEKLDILGKRREKDLEVSWNDRRHKLDQCL------ELQ 559
Query: 1125 LAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDL 946
L F + +W E L +SL+ + +L H +F ++LS E+ ++
Sbjct: 560 L-FLRDCEQAEAWMGAREAFLASEGLTDSLDSVESLIKKHEDFDKALSLQEQKINAIESF 618
Query: 945 DRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKL 766
+++ + + P D + + W +L+ + E+ +L H Q +F++
Sbjct: 619 PQQLINNDHYDGPAIGTKRDQVLERWHSLKAALIEKRSKLGESHTLQ--------QFSRD 670
Query: 765 ANAFHAWLT 739
A+ AW++
Sbjct: 671 ADEVEAWIS 679
Score = 163 bits (413), Expect = 5e-38
Identities = 160/708 (22%), Positives = 304/708 (42%), Gaps = 36/708 (5%)
Frame = -1
Query: 5355 RLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRN 5176
R+ + TGEQ++D GHFA D I +++ + W L D ++++ L ++ QQ+ +
Sbjct: 5 RIKMVTKTGEQMLDEGHFANDEISAKVKGLEEKWKNLKDKSSQRKDDLEDSLEAQQYFAD 64
Query: 5175 IEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQE 4996
+ E+W+ E E VASEDYGKD S ++ KK + +D A+ ++ +K+ A+ ++
Sbjct: 65 ANEAESWMQEKEPIVASEDYGKDEDSAESQLKKHKTLMADLVAYRTTIEMLKKQAEGCRQ 124
Query: 4995 EEHFNAPVIVRKQENLQQRY-NALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQ 4819
++ + E++ + Y AL D +EK R++ + + ++ W E
Sbjct: 125 QD-------IPISEDVGKEYVVALYDYMEKSPREVSMKKGDVLVLLNSSNKDWWKVEVND 177
Query: 4818 VAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKL 4639
G +KK A A+ A+ + +E AN M +Q
Sbjct: 178 RQGFVPAA--------YVKKMDA--AQSASQANLVED----ANIMRRQ------------ 211
Query: 4638 AQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSA 4459
+ ++ L KA R+ L++S++ H + +AN+ W+++K +V S + G D +
Sbjct: 212 ENIEQEYQALLDKAGVRKEALEESVKRHSLVREANDLIQWVNDKAAVVESAEVGDDLEQV 271
Query: 4458 EALLKKHRALLSDLEAFKGTIED------------------LRKQASQCKYQEQPMGQL- 4336
E L KK DL+A + + + L ++ + + Q + +L
Sbjct: 272 EVLQKKFDDFQKDLKANESRLLEINTILETLDLEKVPELTLLSQKVNDLNTEWQALQKLT 331
Query: 4335 -GRDCVLALYDYQEKSPREVSMKK---GDVLTLLNASN--RDWWKVEVNDR--QGFVP-- 4186
R LA ++ R+ K D LN N D V+ R QG
Sbjct: 332 DDRSASLATAHEVQRFFRDADETKDWIDDKNKALNTENFGHDLHSVQALQRKHQGLERDL 391
Query: 4185 AAYVKRIE--PGTAQQHAQ---QQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGY 4021
A K+++ TA + Q Q I K++EI++ + L RK KL ++
Sbjct: 392 NALGKQVQTLDETADRLVQTHPDQAEPIVAKRAEIDEAWHTLQDRANARKAKLMDSYDLQ 451
Query: 4020 QLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIA 3841
+ L + DL W + + A E+ D+ E L ++ + +++ Q
Sbjct: 452 RFLSDFRDLMSWTNGMKTLVASDELAKDVTGAEALLERHQELHTEMEPRAGTFQAFEAFG 511
Query: 3840 TALTSVGQTETAVRIRQQIEDL-NARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDW 3664
L + ++++++ L R + L +L E+Q F RD ++ W
Sbjct: 512 QELIKNDHYAASPEVQEKLDILGKRREKDLEVSWNDRRHKLDQCLELQLFLRDCEQAEAW 571
Query: 3663 IQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAE 3484
+ ++ L SE L SV++L +KHE ++ L+ KI +++ +L +
Sbjct: 572 MGAREAFLASEGLTDSLDSVESLIKKHEDFDKALSLQEQKINAIESFPQQLINNDHYDGP 631
Query: 3483 QIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIA 3340
I + ++ E+W+ L + ++ KL +S+ Q+F D ++ WI+
Sbjct: 632 AIGTKRDQVLERWHSLKAALIEKRSKLGESHTLQQFSRDADEVEAWIS 679
Score = 159 bits (403), Expect = 7e-37
Identities = 102/483 (21%), Positives = 216/483 (44%), Gaps = 10/483 (2%)
Frame = -1
Query: 7194 DIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENFR 7015
+I +R++ + Y D + +++ LEE+ + R+A++L W+ +K +
Sbjct: 206 NIMRRQENIEQEYQALLDKAGVRKEALEESVKRHSLVREANDLIQWVNDKAAVVESAEVG 265
Query: 7014 DP-SNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWX 6838
D ++ +K + F+ +++A+ + ++ + + +++ +L+ W
Sbjct: 266 DDLEQVEVLQKKFDDFQKDLKANESRLLEINTILETLDLEKVPELTLLSQKVNDLNTEWQ 325
Query: 6837 XXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFD 6658
+ L A ++ F R DE WI +K + E+ G DL V+ LQRK
Sbjct: 326 ALQKLTDDRSASLATAHEVQRFFRDADETKDWIDDKNKALNTENFGHDLHSVQALQRKHQ 385
Query: 6657 DFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLF 6478
++L ++ +++ AD+LV+ + + I KR ++++AWH L A RK L
Sbjct: 386 GLERDLNALGKQVQTLDETADRLVQTHPDQAEPIVAKRAEIDEAWHTLQDRANARKAKLM 445
Query: 6477 GAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKML 6298
++ +QRF D + ++W ++SD+ +D+ +AL +H+ ++ G
Sbjct: 446 DSYDLQRFLSDFRDLMSWTNGMKTLVASDELAKDVTGAEALLERHQELHTEMEPRAGTFQ 505
Query: 6297 QLEKEAHKLAET-HPDRAEAIHQKND--------DTKAAWNALKEKAQHRKDGLERSFQL 6145
E +L + H + + +K D D + +WN R+ L++ +L
Sbjct: 506 AFEAFGQELIKNDHYAASPEVQEKLDILGKRREKDLEVSWN-------DRRHKLDQCLEL 558
Query: 6144 HRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASA 5965
FL D +W+G +A + ++ L + E+L++ H++ + + N S
Sbjct: 559 QLFLRDCEQAEAWMGAREAFLASEGLTDSLDSVESLIKKHEDFDKALSLQEQKINAIESF 618
Query: 5964 GQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWM 5785
Q+L+ + P + K +++ SL E+R + LQ F RD ++ E W+
Sbjct: 619 PQQLINNDHYDGPAIGTKRDQVLERWHSLKAALIEKRSKLGESHTLQQFSRDADEVEAWI 678
Query: 5784 NKQ 5776
+++
Sbjct: 679 SEK 681
Score = 39.7 bits (91), Expect = 1.1
Identities = 20/50 (40%), Positives = 27/50 (54%)
Frame = -1
Query: 7191 IHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKL 7042
I +R +VL + K KR +L E+ Q F RDADE+ WI EK+
Sbjct: 633 IGTKRDQVLERWHSLKAALIEKRSKLGESHTLQQFSRDADEVEAWISEKI 682
>gi|45552921|ref|NP_995987.1| CG12008-PC [Drosophila melanogaster]
gi|45445783|gb|AAS64957.1| CG12008-PC [Drosophila melanogaster]
Length = 4207
Score = 756 bits (1952), Expect = 0.0
Identities = 577/2347 (24%), Positives = 1044/2347 (43%), Gaps = 92/2347 (3%)
Frame = -1
Query: 7128 KRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENFRDPSNLQAKIQKHEA-------F 6970
K+ L + Q F R+AD+++ T E F + +NL A + + EA F
Sbjct: 1283 KQKWLLQCVDLQMFNREADKIDA------TTKSHEAFLEYNNLGASLDEVEAILKRHLDF 1336
Query: 6969 EAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQA 6790
E + A K + + +I ++H+ S++I R ++ + LQ +
Sbjct: 1337 EKSLMAQDKILKGFSDNADKLISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQAS 1396
Query: 6789 LKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEI 6610
F + D++ W+++K T + ++ DL ++ +K F +EL ++ ++ +
Sbjct: 1397 KDFHKFAAEADDLKVWLQDK-TRIAGDENYRDLSNLPRKLQKHQAFERELRANEGQLRNV 1455
Query: 6609 NQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETL 6430
+ LV+ G+ ++ + D+N W L TL+ + L A + NR ++
Sbjct: 1456 TKDGQALVQAGNRV-PEVESRVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAK 1514
Query: 6429 AWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDR 6250
+ E D AL S D G DL + + L K + E ++ + K+ +L +A
Sbjct: 1515 KKVDELDSALRSGDVGNDLRSCKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFN 1574
Query: 6249 AEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADE 6070
A+ I + + + L++ Q R+ LE S H+F+ + WI + ++E
Sbjct: 1575 AQNIEAGTKELQQRFKDLRDPTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKSNE 1634
Query: 6069 LAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHE 5890
L +++ A++L + H++ + EI N+ AGQ L+ PE +V+ ++L+
Sbjct: 1635 LGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALVAGQSLISQQHPEREQVESLCQQLEQA 1694
Query: 5889 KSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKK 5710
L ER + + Q + D + E+W+ ++ L +T+ G DS L+ K
Sbjct: 1695 WQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLLTK 1754
Query: 5709 HEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNA 5530
H+ E L + + ++ H + +A R
Sbjct: 1755 HKTIELELDTYSGIVTEMGHSCAAMVAANHPDSKVLAAKQQLIEKMLKSLHKLASQRQGR 1814
Query: 5529 LKESYKRQTFDRDCDEMVSWITEKLSTARDDSY-LDPTNIRGKLQKHINFEQELKANENR 5353
L ES + + + DE+ WI E+ A + Y D +++ K + + ++ +R
Sbjct: 1815 LMESLYKHEYFLESDEVEQWIREQEQAASSEDYGQDFEHLQLLQNKFDDLKHRVEVGADR 1874
Query: 5352 LDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNI 5173
+D +++IDS A+ + R Q+ W L+ N++ KL AG +F+R++
Sbjct: 1875 VDQCELLAKKLIDSESPYANEVEKRQEQLRTSWENLLQLLNQREQKLHAAGEIHRFHRDV 1934
Query: 5172 EDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEE 4993
+ + + + S++ G+DL S L +K E+D A ++ + + + + Q +
Sbjct: 1935 AEALFRIQD-KNAALSQELGRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSVRLQAK 1993
Query: 4992 EHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVA 4813
NA I ++Q+ + +N L++ R +L S D+ D ++W
Sbjct: 1994 YPSNASAIAQQQDKVVAAWNDLKERSTARGDRLAASSDLQTFLTDVRDIVSWSSNLRAAL 2053
Query: 4812 GSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQ 4633
+ D G L + A+ EI + + ++ ++ M+Q GH+ A ++ +K A
Sbjct: 2054 QAEEHVSDAAGATALKIQHDAIYGEIEAREDKFRYLNELSDSMVQTGHYAAADVEEKCAA 2113
Query: 4632 LRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEA 4453
+ D + L + K++ L+ + +L DA + D S ++ + S+D+G+ + +
Sbjct: 2114 MLDERQKLHAAWNKKKIMLEQKIDLFCFLRDAKQIDNLSSSQQAALSSSDFGQTVEDVQN 2173
Query: 4452 LLKKH----RALLSDLEAFKGTIEDLRKQASQCKYQEQPM-------------------- 4345
++KH R + + E E RK Q Y +
Sbjct: 2174 KIRKHDEFERLIQTQEEKVSLLQEHGRKLIEQRHYDSANIQTILQGVLARRQKVKDLCAV 2233
Query: 4344 -----------GQLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQ 4198
+ RDC A Y EK + + D + +N D ++ Q
Sbjct: 2234 RRYKLEDALLYAKFVRDCAEAKYWINEKQKK----LEADAASYAEVTNLDEKIKKLQKHQ 2289
Query: 4197 GFVPAAYVKRIEPGTAQQHAQQQVNSIG----GKQSE-----------IEDKYQRLMMLG 4063
F A Q Q++ G KQ E + + +Q L+
Sbjct: 2290 AFQAEV--------AANQGRIQEIQDTGVILLSKQHESSPEIKRAIEIVLEAWQGLLAEL 2341
Query: 4062 ETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDL 3883
E R R LEEA + + + + WI+ +E + + G DLE L +K DD D+
Sbjct: 2342 EQRGRGLEEAQDSLEFNSQLDKIEAWIRDKEMMVQASDTGRDLEHCNALMRKLDDVDSDM 2401
Query: 3882 KANEVRLQEMNQIATALTSVGQTETAVR-IRQQIEDLNARWRALXXXXXXXXXQLGSAHE 3706
+ ++ R++ +NQ+A L + Q + + ++ +D N WR L LG A+E
Sbjct: 2402 RVDDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYNWRQLQGALNAYRALLGGANE 2461
Query: 3705 VQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDE 3526
+ F+RDVD+T D I EK A+ S D GRDL +V+AL R+ E +ERD++A+ KI +
Sbjct: 2462 IHVFNRDVDDTADRIAEKSLAMSSTDTGRDLAAVEALIRREEALERDMSAVKQKIDQHET 2521
Query: 3525 KANRLRQSHPE-AAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQ 3349
A L + +PE A+ I EL++ W L + + R+ L ++Y +F+SD ++L
Sbjct: 2522 AAEFLIKKYPERGAQHIERKLEELHKSWGNLQALSVKRQSILNEAYLAHKFVSDVKELEL 2581
Query: 3348 WIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAA 3169
W+ M + +++ + + + E LE HQE + EI+ R F Q G QL
Sbjct: 2582 WVNDMIKKMNNTQSPSTINDCETQLELHQERKVEIEGRQEAFAGLKQQGEQLSKRPQQQQ 2641
Query: 3168 GD-IENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQED 2992
D + L + E + L +AW R L + +LQLF EQ + W++ +EAFL +D
Sbjct: 2642 PDNVRKYLLVLEELHQTLNEAWSERARDLTEAHQLQLFKAQVEQVEIWLANKEAFLNNDD 2701
Query: 2991 PSGDN---VESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILD 2821
GD+ VE L+KKH++F+K ++ + + L+ FA S+++ D+ + K IL
Sbjct: 2702 -LGDSYTAVERLLKKHDEFEKLLHA--DHVDTLQKFANSILEGEPKDADLIREKLAYILR 2758
Query: 2820 RWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNIQQKHQK 2641
R L E +++ +L +S LQ+F R EI+ W+ +K Q+A +ENYR+P+N+Q K QK
Sbjct: 2759 RKQKLLELSEERKQRLTQSHQLQEFLRSLYEIDRWLVQKLQVALDENYREPSNLQSKIQK 2818
Query: 2640 QQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKS 2461
AF+AEL +NS R+ ++I G LI E A +L L W L + K
Sbjct: 2819 HAAFDAELLSNSPRVQSVIHEGERLIRGDHFAKDEIAQQVQL--LEGDWLKLKGASQTKK 2876
Query: 2460 YRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQ 2281
+L++A +F +V + W+ EVE+ L SEDYGKDLA+V NLLKKH LEAD+ H
Sbjct: 2877 DKLQQAYDALAFNRSVDEFNNWMDEVELQLSSEDYGKDLAAVSNLLKKHERLEADVAHHG 2936
Query: 2280 DRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFR 2101
+ ++ ++ + + + F +I ER + RY+ + + RR+ L +L++ QF R
Sbjct: 2937 ELADQLKQKDEQFFQAEHFLRHEIHERATVSIRRYNTLHEPLGIRRENLEDSLSLQQFLR 2996
Query: 2100 DIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELL 1921
D +DE W+ EK+L+ S D G L VQ L++KH ++ EL S EP + + +G++++
Sbjct: 2997 DAEDELQWLAEKQLVAGSQDLGTSLLSVQGLQKKHNSLEAELTSQEPLIQALLQRGQQMI 3056
Query: 1920 RSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNE 1741
R + +Q++ + E L++ Q+RDL R RL ++ Q F + E +AWM E
Sbjct: 3057 R---DNHFASEQLQYKSELLQKQLVQLRDLAAIRRLRLLDAVESQLFYVEANEADAWMRE 3113
Query: 1740 KQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIK 1561
K+ +L S ++G + VQG KK + Q +L K + + LI + + +I
Sbjct: 3114 KRPVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPSIEKVAKLATGLIERNHFDSSNIA 3173
Query: 1560 QRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDL 1381
++ Q+ ++ +A+ R ++L + +++ + + + W+ ++ SED+G D+
Sbjct: 3174 EKNAQVGQEYEDLLRLAKERESRLGECKKLFEYLRETEELHEWVGDQMAVTASEDYGEDV 3233
Query: 1380 SSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNL 1201
V+ L+ E+F + LNA E ++ E D+L+ + +I+ + Q W+ L
Sbjct: 3234 EHVEQLILAFESFVSNLNANEAR-VEACLERGDRLIQENNPYRSSIKSKRDETKQLWEEL 3292
Query: 1200 L----AHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLE 1033
A +A E + L K AS + E+ +D LE
Sbjct: 3293 KDLVHARQDALAGAKQVHVYDRVADETIQLINEKDASLIS---EDYGQD---------LE 3340
Query: 1032 EIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQR 853
I+AL H F+ L + + ++ + D + W +L+
Sbjct: 3341 SIQALGRKHQVFESELVGIQGQVDSVLAEAAKLGEIYPDAKEHIEVKRDETVEAWTDLKE 3400
Query: 852 IIKEREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEMMEAGGTLEEQLDAVER 673
R+ +L++ Q Q D+ R A + N A +T AG L L + +
Sbjct: 3401 KTAARKNKLSQAEQLQSYFDEYRDLIAWI-NEMLAKITAPELANSVAGAEL--LLASTKD 3457
Query: 672 KAKEIKANKGQLRQIEEKGAMLERNLILDNRYTEHST---VGIAQAWDQL---------- 532
EI+ + G + LI + + H + + QA +L
Sbjct: 3458 HDTEIRTRDETFAKFAANG----QQLIKEKHFLAHEVEDKIKVLQARHELLKHTLNKRRE 3513
Query: 531 -------DQLAMRMQHNLEQQIQAR----NQSGVSEEALREFSMMFKHFDKEKTGRLDHQ 385
QL ++ LEQ I +R + + + + ++ +H D EKT +
Sbjct: 3514 IYELNLDTQLFLKDAEILEQWISSREPQLKDTKLGDSIPQVEDLLRRHEDFEKTVAAQEE 3573
Query: 384 QFKSCLR 364
+F++ R
Sbjct: 3574 KFQAIKR 3580
Score = 755 bits (1949), Expect = 0.0
Identities = 547/2178 (25%), Positives = 1007/2178 (46%), Gaps = 67/2178 (3%)
Frame = -1
Query: 6924 KTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILY 6745
+T I N ++ ++KR + ++ + + L+ ++ L F R+CD+
Sbjct: 936 RTSTQSINEN---ADSVEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEK 992
Query: 6744 WIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEH 6565
W++EKE + +++ E V+ +RKF+ F+ +L R+ EI+ A D +GHS+
Sbjct: 993 WMKEKERMIKSDEG----EGVDNAKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQL 1048
Query: 6564 DQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDY 6385
D+I ++ ++ W RLN A R++ L GA V+ FNR DE W+ EK L L +
Sbjct: 1049 DKIIARQRQIHQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVI 1108
Query: 6384 GRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAW 6205
DL VQALQR+H+ ER+LA +E K+ ++ + + +P + ++ + + + W
Sbjct: 1109 TPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQDMW 1168
Query: 6204 NALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESH 6025
++++ ++ +E F + L++WI +K + ADE A+DV A LL+ H
Sbjct: 1169 QQVQQRGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKH 1228
Query: 6024 QEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILY 5845
+ +I A F + G++L + G P E +E+L E+ ++ W E++
Sbjct: 1229 NDLGDDIRAHDTEFVEVIQLGKQLSD-GKPNMAETVAVIERLKAEQDAIHRGWAEKQKWL 1287
Query: 5844 EQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKI 5665
QC+DLQ+F R+ ++ + EAFL +LG SLD VE ++K+H DFEKSL AQ++ +
Sbjct: 1288 LQCVDLQMFNREADKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLDFEKSLMAQDKIL 1347
Query: 5664 NALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCD 5485
+ A KLI HY + + + R L+ S F + D
Sbjct: 1348 KGFSDNADKLISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEAD 1407
Query: 5484 EMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGH 5305
++ W+ +K A D++Y D +N+ KLQKH FE+EL+ANE +L ++ G+ ++ +G+
Sbjct: 1408 DLKVWLQDKTRIAGDENYRDLSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQAGN 1467
Query: 5304 FAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVAS 5125
+ + R+ +N W +L+ + KG KL +A ++++ NR++ED + + EL+ + S
Sbjct: 1468 RVPE-VESRVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDSALRS 1526
Query: 5124 EDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQ 4945
D G DL S ++L K ++ES+ + +V + HFNA I + LQ
Sbjct: 1527 GDVGNDLRSCKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQ 1586
Query: 4944 QRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLI 4765
QR+ LRDP ++R+ KL ES ++ +++ E WI E A S G++L Q+L
Sbjct: 1587 QRFKDLRDPTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKSNELGQNLHQAQSLH 1646
Query: 4764 KKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRR 4585
KK + L AEI H I A +I Q H ++ QL W+ L+ +R
Sbjct: 1647 KKHKKLEAEIKGHQPMINKALVAGQSLISQQHPEREQVESLCQQLEQAWQDLERHCGERS 1706
Query: 4584 TDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFK 4405
LD SL+A QYL DA E ++W+ E+ ++ ST+YG+D DSA LL KH+ + +L+ +
Sbjct: 1707 RKLDMSLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLLTKHKTIELELDTYS 1766
Query: 4404 GTIEDLRKQASQCKYQEQPMGQLGRDCVLALYDYQEKSPREVSMKKGDVLT-------LL 4246
G + ++ + P ++ + + + S ++G ++ L
Sbjct: 1767 GIVTEMGHSCAAMVAANHPDSKVLAAKQQLIEKMLKSLHKLASQRQGRLMESLYKHEYFL 1826
Query: 4245 NASNRDWWKVEVNDR-------QGFVPAAYVK--------RIEPGT-----AQQHAQQQV 4126
+ + W E Q F ++ R+E G + A++ +
Sbjct: 1827 ESDEVEQWIREQEQAASSEDYGQDFEHLQLLQNKFDDLKHRVEVGADRVDQCELLAKKLI 1886
Query: 4125 NS-------IGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREA 3967
+S + +Q ++ ++ L+ L R++KL A + ++ R+ + I+ + A
Sbjct: 1887 DSESPYANEVEKRQEQLRTSWENLLQLLNQREQKLHAAGEIHRFHRDVAEALFRIQDKNA 1946
Query: 3966 VAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQ 3787
A QE+G DL L +K + F+ DL A E +LQ + + + L A I QQ
Sbjct: 1947 -ALSQELGRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSVRL-QAKYPSNASAIAQQ 2004
Query: 3786 IEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRS 3607
+ + A W L +L ++ ++Q F DV + W AL +E+ D
Sbjct: 2005 QDKVVAAWNDLKERSTARGDRLAASSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAG 2064
Query: 3606 VQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSK 3427
AL+ +H+ + ++ A DK + L+E ++ + Q+ AA + + + ++ +L +
Sbjct: 2065 ATALKIQHDAIYGEIEAREDKFRYLNELSDSMVQTGHYAAADVEEKCAAMLDERQKLHAA 2124
Query: 3426 ANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTE 3247
N +K L D FL D + + +S +SS + V + + +H E+
Sbjct: 2125 WNKKKIMLEQKIDLFCFLRDAKQIDNLSSSQQAALSSSDFGQTVEDVQNKIRKHDEFERL 2184
Query: 3246 IDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLEL 3067
I ++ + G +L+ HY + +I+ LQGV R+ ++D RR L+ L
Sbjct: 2185 IQTQEEKVSLLQEHGRKLIEQRHYDSANIQTILQGVLARRQKVKDLCAVRRYKLEDALLY 2244
Query: 3066 QLFYRDCEQADTWMSAREAFLAQEDPSGDNVESL------IKKHEDFDKAINTQEEKIKG 2905
F RDC +A W++ ++ L + S V +L ++KH+ F + + +I+
Sbjct: 2245 AKFVRDCAEAKYWINEKQKKLEADAASYAEVTNLDEKIKKLQKHQAFQAEVAANQGRIQE 2304
Query: 2904 LKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEI 2725
++ L+ H SP + R + +L+ W GL L Q+ L E+Q +F+ D+I
Sbjct: 2305 IQDTGVILLSKQHESSPEIKRAIEIVLEAWQGLLAELEQRGRGLEEAQDSLEFNSQLDKI 2364
Query: 2724 ENWMTEKFQIAQ-EENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKC 2548
E W+ +K + Q + RD + +K ++++ + R+ I Q + LI A+
Sbjct: 2365 EAWIRDKEMMVQASDTGRDLEHCNALMRKLDDVDSDMRVDDQRVKHINQLADKLINQAQV 2424
Query: 2547 GGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQ 2368
+V R K N W L L AN+ F V D + E + +
Sbjct: 2425 PADTQSVDKRRKDFNYNWRQLQGALNAYRALLGGANEIHVFNRDVDDTADRIAEKSLAMS 2484
Query: 2367 SEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERR-KL 2191
S D G+DLA+VE L+++ LE D+ A + ++ + A+ L++ +G Q ER+ +
Sbjct: 2485 STDTGRDLAAVEALIRREEALERDMSAVKQKIDQHETAAEFLIKKYPERGAQHIERKLEE 2544
Query: 2190 IADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQN 2011
+ + ++ ++ R+ L++A H+F D+ + E W+ + +++ + +
Sbjct: 2545 LHKSWGNLQALSVKRQSILNEAYLAHKFVSDVKELELWVNDMIKKMNNTQSPSTINDCET 2604
Query: 2010 LRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDL 1831
H+ E+ + + +K +GE+L + + D ++K + LE+ + +
Sbjct: 2605 QLELHQERKVEIEGRQEAFAGLKQQGEQLSKRPQQQ--QPDNVRKYLLVLEELHQTLNEA 2662
Query: 1830 TGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVD 1651
R + L E+ Q F VE+ E W+ K+ L +D+ G++ V+ LLKKHD F +
Sbjct: 2663 WSERARDLTEAHQLQLFKAQVEQVEIWLANKEAFLNNDDLGDSYTAVERLLKKHDEF--E 2720
Query: 1650 LELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAY 1471
LH V L ++++ A I+++ + R ++ ++E R +L +
Sbjct: 2721 KLLHADHVDTLQKFANSILEGEPKDADLIREKLAYILRRKQKLLELSEERKQRLTQSHQL 2780
Query: 1470 LQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITE 1291
+F+ ++ W+ +K Q E++ R+ S++Q + K AFDA L + +Q +
Sbjct: 2781 QEFLRSLYEIDRWLVQKLQVALDENY-REPSNLQSKIQKHAAFDAELLS-NSPRVQSVIH 2838
Query: 1290 LKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELY--LAF 1117
++L+ +H I ++ + W L S+ ++ ++++ Y LAF
Sbjct: 2839 EGERLIRGDHFAKDEIAQQVQLLEGDWLKLKGASQTKK----------DKLQQAYDALAF 2888
Query: 1116 AKKASTFNSWFENAEEDLT------DPVRCNSL----EEIRALRDAHGEFQRSLSSAEED 967
+ FN+W + E L+ D ++L E + A HGE L +E
Sbjct: 2889 NRSVDEFNNWMDEVELQLSSEDYGKDLAAVSNLLKKHERLEADVAHHGELADQLKQKDEQ 2948
Query: 966 FRQLQDLDRR---------IKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQEL--AR 820
F Q + R I+ +N P + LED+ +LQ+ +++ E EL
Sbjct: 2949 FFQAEHFLRHEIHERATVSIRRYNTLHEP-LGIRRENLEDS-LSLQQFLRDAEDELQWLA 3006
Query: 819 EHQRQEENDKLRREFAKLANAFHAWLTNTRQEMMEAGGTLEEQL--DAVERKAKEIKANK 646
E Q + L + + +EA T +E L ++R + I+ N
Sbjct: 3007 EKQLVAGSQDLGTSLLSVQG------LQKKHNSLEAELTSQEPLIQALLQRGQQMIRDNH 3060
Query: 645 GQLRQIEEKGAMLERNLI 592
Q++ K +L++ L+
Sbjct: 3061 FASEQLQYKSELLQKQLV 3078
Score = 637 bits (1643), Expect = e-180
Identities = 404/1525 (26%), Positives = 749/1525 (48%), Gaps = 100/1525 (6%)
Frame = -1
Query: 5472 WITEKLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAAD 5293
++ E + D YL + L+KH ++ A R +D+ + E++ + +
Sbjct: 411 YLKEMIQVLSDPRYL--RQVDATLKKHEAISADILARVERFNDLTAMAEELDRENYHGKE 468
Query: 5292 HIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYG 5113
+ R ++V W +L++ + L + N R I + EL+ Q ASED G
Sbjct: 469 RVRRREQEVMAKWRQLLELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQFASEDVG 528
Query: 5112 KDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYN 4933
L+ V+ L + L E N + + + + A ++ EH +A ++ ++ +L++ Y+
Sbjct: 529 PHLLGVEELLQAHSLQELQVNTYGETLKRFNRQALPYKSSEHKDAALLAQRLADLEEAYS 588
Query: 4932 ALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQ 4753
L R+ +L E+ + D ++E +W+ +K+++ + +DL V +L +K +
Sbjct: 589 ELLRRSAARRARLEEARNFHHFMEDYDNEESWLVDKQRICKTGITAKDLRAVLSLQQKHK 648
Query: 4752 ALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLD 4573
AL EI + + +S+A +I + H + EI+ ++ L ++W+ L++ E RR L+
Sbjct: 649 ALEDEIKSRKPKSGQMSTAGKRLIGEQHPRSSEIQSRIDSLAEHWQALEALVELRRRQLE 708
Query: 4572 DSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIE 4393
D+ +A+Q+ +DANEA++W++EK +V S DYG DE SA+ALL++HR L +L A+ G I
Sbjct: 709 DAAEAYQFYTDANEAESWLNEKIALVNSRDYGNDEPSAQALLQRHRDLQGELNAYSGDIL 768
Query: 4392 DLRKQ------ASQCKYQ----EQPMGQLGRD---------------------------- 4327
+L +Q A C + E + ++ ++
Sbjct: 769 NLNQQADKLIKAGICTLELSAAEPELPEVEQEEWVNETRLVPKEVWEDEWVEKLEHKKVT 828
Query: 4326 ------CVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEV-NDRQGFVPAAYVKR 4168
V +L+ ++ + + M KG+V+ L + +N DWW V N +GFVPA YV+
Sbjct: 829 ETKMLPHVKSLFPFEGQG---MKMDKGEVMLLKSKTNDDWWCVRKDNGVEGFVPANYVRE 885
Query: 4167 IEPG-----------------------------------------------TAQQHAQQQ 4129
+EP T+ Q +
Sbjct: 886 VEPRPVACIVPKAEKVKSLQKVKKTILVRQVVPVKRIKPVSVAPKPLVQRRTSTQSINEN 945
Query: 4128 VNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQE 3949
+S+ +Q I Y L + + R LE++ + RE +D +W+K +E + E
Sbjct: 946 ADSVEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKERMIKSDE 1005
Query: 3948 IGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNA 3769
E V+ ++KF+ F DL A R++E++ G ++ I +Q ++
Sbjct: 1006 G----EGVDNAKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDKIIARQ-RQIHQ 1060
Query: 3768 RWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQR 3589
W+ L L A V+ F+R DE + W+ EK LD+ DLR+VQALQR
Sbjct: 1061 IWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVITPDLRTVQALQR 1120
Query: 3588 KHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKE 3409
+H+ +ER+LA + DK+ + N ++ ++P + + Q+E+ + W ++ + ++ +
Sbjct: 1121 RHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQDMWQQVQQRGSDLRN 1180
Query: 3408 KLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAA 3229
++ Q F + + L+ WI S+ +++ E A DV A LL++H + +I +
Sbjct: 1181 RIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDLGDDIRAHDT 1240
Query: 3228 TFQAFDQFGNQLLNSHHYAAGDIE--NRLQGVNEARKGLEDAWVARRNILDQCLELQLFY 3055
F Q G QL + A + RL+ +A + W ++ L QC++LQ+F
Sbjct: 1241 EFVEVIQLGKQLSDGKPNMAETVAVIERLKAEQDA---IHRGWAEKQKWLLQCVDLQMFN 1297
Query: 3054 RDCEQADTWMSAREAFLAQED--PSGDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESL 2881
R+ ++ D + EAFL + S D VE+++K+H DF+K++ Q++ +KG A+ L
Sbjct: 1298 READKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLDFEKSLMAQDKILKGFSDNADKL 1357
Query: 2880 IKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKF 2701
I N+HYDS + +R+Q+L + +K+ +++ L S+ +F+ +AD+++ W+ +K
Sbjct: 1358 ISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKT 1417
Query: 2700 QIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSA 2521
+IA +ENYRD +N+ +K QK QAFE EL AN ++ + + G L++ G V +
Sbjct: 1418 RIAGDENYRDLSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQ---AGNRVPEVES 1474
Query: 2520 RLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLA 2341
R+ LN +W L+ + +K +L++A Q+ +++D + + E++ L+S D G DL
Sbjct: 1475 RVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDSALRSGDVGNDLR 1534
Query: 2340 SVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKK 2161
S ++L+ K +LE++I +V E+ D + F Q I K + R+ ++
Sbjct: 1535 SCKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQQRFKDLRD 1594
Query: 2160 MATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDT 1981
RR KL ++LN H+F ++D E WI E S++ G++L Q+L +KH++++
Sbjct: 1595 PTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKSNELGQNLHQAQSLHKKHKKLEA 1654
Query: 1980 ELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDE 1801
E+ H+P ++ + G+ L+ ++ +Q++ + LEQ+W + G R ++LD
Sbjct: 1655 EIKGHQPMINKALVAGQSLI---SQQHPEREQVESLCQQLEQAWQDLERHCGERSRKLDM 1711
Query: 1800 SEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVAD 1621
S Q +L D E E+W+ E+ +L S +G + LL KH T +++L+ + V +
Sbjct: 1712 SLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLLTKHKTIELELDTYSGIVTE 1771
Query: 1620 LINKGDTLIHNGNHHAPHIKQRCDQLRARLIE-IESMAEGRLAKLRDNSAYLQFMWKCDV 1444
+ + ++ NH + QL ++++ + +A R +L ++ ++ + D
Sbjct: 1772 MGHSCAAMV-AANHPDSKVLAAKQQLIEKMLKSLHKLASQRQGRLMESLYKHEYFLESDE 1830
Query: 1443 VESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITE---LKDQLV 1273
VE WI E+EQ SED+G+D +Q+L Q FD L G R+ + L +L+
Sbjct: 1831 VEQWIREQEQAASSEDYGQDFEHLQLL---QNKFD-DLKHRVEVGADRVDQCELLAKKLI 1886
Query: 1272 SSEHQQSPAIEKRHTNVIQRWQNLL 1198
SE + +EKR + W+NLL
Sbjct: 1887 DSESPYANEVEKRQEQLRTSWENLL 1911
Score = 610 bits (1573), Expect = e-172
Identities = 410/1364 (30%), Positives = 666/1364 (48%), Gaps = 44/1364 (3%)
Frame = -1
Query: 7176 QEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEE--NFRDPSN 7003
Q VL KD +R +LE+A + F RD E WI EK + + + ++ + +N
Sbjct: 2218 QGVLARRQKVKDLCAVRRYKLEDALLYAKFVRDCAEAKYWINEKQKKLEADAASYAEVTN 2277
Query: 7002 LQAKI---QKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXX 6832
L KI QKH+AF+AEV A+ I + TG ++ H +S IK+ +E + W
Sbjct: 2278 LDEKIKKLQKHQAFQAEVAANQGRIQEIQDTGVILLSKQHESSPEIKRAIEIVLEAWQGL 2337
Query: 6831 XXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDF 6652
+G L++A L F Q D+I WIR+KE V A D G DLEH L RK DD
Sbjct: 2338 LAELEQRGRGLEEAQDSLEFNSQLDKIEAWIRDKEMMVQASDTGRDLEHCNALMRKLDDV 2397
Query: 6651 LKELGNHQYRINEINQAADKLVEEGHSEHD--QIYKKRDDVNDAWHRLNTLAATRKEGLF 6478
++ R+ INQ ADKL+ + D + K+R D N W +L + L
Sbjct: 2398 DSDMRVDDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYNWRQLQGALNAYRALLG 2457
Query: 6477 GAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKML 6298
GA+++ FNRD D+T I EK LA+SS D GRDL V+AL R+ E ERD++A++ K+
Sbjct: 2458 GANEIHVFNRDVDDTADRIAEKSLAMSSTDTGRDLAAVEALIRREEALERDMSAVKQKID 2517
Query: 6297 QLEKEAHKLAETHPDR-AEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYR 6121
Q E A L + +P+R A+ I +K ++ +W L+ + R+ L ++ H+F++D +
Sbjct: 2518 QHETAAEFLIKKYPERGAQHIERKLEELHKSWGNLQALSVKRQSILNEAYLAHKFVSDVK 2577
Query: 6120 DLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMG 5941
+L W+ DM + + + E LE HQE K EI+ R ++F G++L +
Sbjct: 2578 ELELWVNDMIKKMNNTQSPSTINDCETQLELHQERKVEIEGRQEAFAGLKQQGEQLSKRP 2637
Query: 5940 IPESPE-VQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFL 5764
+ P+ V++ L L+ +L W ER + LQLF EQ E W+ +EAFL
Sbjct: 2638 QQQQPDNVRKYLLVLEELHQTLNEAWSERARDLTEAHQLQLFKAQVEQVEIWLANKEAFL 2697
Query: 5763 ANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXX 5584
N DLGDS +VE L+KKH++FEK L A + ++ L +FA +++G+ AD + E
Sbjct: 2698 NNDDLGDSYTAVERLLKKHDEFEKLLHA--DHVDTLQKFANSILEGEPKDADLIREKLAY 2755
Query: 5583 XXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGK 5404
R L +S++ Q F R E+ W+ +KL A D++Y +P+N++ K
Sbjct: 2756 ILRRKQKLLELSEERKQRLTQSHQLQEFLRSLYEIDRWLVQKLQVALDENYREPSNLQSK 2815
Query: 5403 LQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKK 5224
+QKH F+ EL +N R+ + GE++I HFA D I +++ + W +L A+ K
Sbjct: 2816 IQKHAAFDAELLSNSPRVQSVIHEGERLIRGDHFAKDEIAQQVQLLEGDWLKLKGASQTK 2875
Query: 5223 GAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAH 5044
KL++A + FNR++++ W+ E+E Q++SEDYGKDL +V NL KK +E+D H
Sbjct: 2876 KDKLQQAYDALAFNRSVDEFNNWMDEVELQLSSEDYGKDLAAVSNLLKKHERLEADVAHH 2935
Query: 5043 NDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLF 4864
+ D +KQ +QF + EHF I + +RYN L +PL R+ L +S Q
Sbjct: 2936 GELADQLKQKDEQFFQAEHFLRHEIHERATVSIRRYNTLHEPLGIRRENLEDSLSLQQFL 2995
Query: 4863 RDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDM 4684
RD EDEL W+ EK+ VAGS + G L+ VQ L KK +L AE+ + + I+++ M
Sbjct: 2996 RDAEDELQWLAEKQLVAGSQDLGTSLLSVQGLQKKHNSLEAELTSQEPLIQALLQRGQQM 3055
Query: 4683 IQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKE 4504
I+ HF + +++ K L+ L+ A RR L D++++ + +ANEADAWM EK
Sbjct: 3056 IRDNHFASEQLQYKSELLQKQLVQLRDLAAIRRLRLLDAVESQLFYVEANEADAWMREKR 3115
Query: 4503 PIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQAS--------QCKYQEQP 4348
P++ S+DYG+DE S + KK L +L AFK +IE + K A+ +
Sbjct: 3116 PVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPSIEKVAKLATGLIERNHFDSSNIAEK 3175
Query: 4347 MGQLGRDCVLALYDYQEKSPREVSMKK---------------GDVLTLLNASNRDWWKVE 4213
Q+G++ L +E+ R KK GD + + AS VE
Sbjct: 3176 NAQVGQEYEDLLRLAKERESRLGECKKLFEYLRETEELHEWVGDQMA-VTASEDYGEDVE 3234
Query: 4212 VNDRQGFVPAAYVKRIEPGTAQ------------QHAQQQVNSIGGKQSEIEDKYQRLMM 4069
++ ++V + A+ Q +SI K+ E + ++ L
Sbjct: 3235 HVEQLILAFESFVSNLNANEARVEACLERGDRLIQENNPYRSSIKSKRDETKQLWEELKD 3294
Query: 4068 LGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKG 3889
L R+ L A + + R A++ + I ++A ++ G DLE ++ L +K F+
Sbjct: 3295 LVHARQDALAGAKQVHVYDRVADETIQLINEKDASLISEDYGQDLESIQALGRKHQVFES 3354
Query: 3888 DLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAH 3709
+L + ++ + A L + + I + ++ W L +L A
Sbjct: 3355 ELVGIQGQVDSVLAEAAKLGEI-YPDAKEHIEVKRDETVEAWTDLKEKTAARKNKLSQAE 3413
Query: 3708 EVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLD 3529
++Q + + + WI E + + + + + L + + ++ +
Sbjct: 3414 QLQSYFDEYRDLIAWINEMLAKITAPELANSVAGAELLLASTKDHDTEIRTRDETFAKFA 3473
Query: 3528 EKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQ 3349
+L + A ++ D + L + L N R+E + D Q FL D L Q
Sbjct: 3474 ANGQQLIKEKHFLAHEVEDKIKVLQARHELLKHTLNKRREIYELNLDTQLFLKDAEILEQ 3533
Query: 3348 WIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQA 3217
WI+S + +L + + E LL RH+++ + ++ FQA
Sbjct: 3534 WISSREPQLKDTKLGDSIPQVEDLLRRHEDFEKTVAAQEEKFQA 3577
Score = 544 bits (1401), Expect = e-152
Identities = 479/2308 (20%), Positives = 974/2308 (41%), Gaps = 62/2308 (2%)
Frame = -1
Query: 7191 IHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENFRD 7012
I RR +VLG KD + ++ L+ ++ F F +AD+L VW+ +K + A +EN+RD
Sbjct: 1368 IGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKTRIAGDENYRD 1427
Query: 7011 PSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXX 6832
SNL K+QKH+AFE E++A+ + N+ K G A++Q + E ++ R+ +L+ W
Sbjct: 1428 LSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQAGNRVPE-VESRVADLNKRWKDL 1486
Query: 6831 XXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDF 6652
KG KL+QA R ++ + E ++ + + D+G DL + L K
Sbjct: 1487 LTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDSALRSGDVGNDLRSCKDLINKQQIL 1546
Query: 6651 LKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGA 6472
E+ ++ E+ D + GH I ++ + L R+ L +
Sbjct: 1547 ESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQQRFKDLRDPTQRRRAKLEES 1606
Query: 6471 HQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQL 6292
+F + D WI E A S++ G++L+ Q+L +KH+ E A ++G +
Sbjct: 1607 LNYHKFVFELDSEFQWINEHLPAAKSNELGQNLHQAQSLHKKHKKLE---AEIKGHQPMI 1663
Query: 6291 EKEA----HKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADY 6124
K +++ HP+R E + + AW L+ R L+ S + ++L D
Sbjct: 1664 NKALVAGQSLISQQHPER-EQVESLCQQLEQAWQDLERHCGERSRKLDMSLKAQQYLFDA 1722
Query: 6123 RDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEM 5944
++ SW+G+ V+ + E +D A LL H+ + E+D + + + +V
Sbjct: 1723 GEIESWLGERNNVLRSTEYGRDRDSAAKLLTKHKTIELELDTYSGIVTEMGHSCAAMVAA 1782
Query: 5943 GIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFL 5764
P+S + K + ++ SL L +R+ + + ++ ++++ E W+ +QE
Sbjct: 1783 NHPDSKVLAAKQQLIEKMLKSLHKLASQRQGRLMESLYKHEYFLESDEVEQWIREQEQAA 1842
Query: 5763 ANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXX 5584
++ D G + ++ L K +D + + ++++ + A KLI + A++V +
Sbjct: 1843 SSEDYGQDFEHLQLLQNKFDDLKHRVEVGADRVDQCELLAKKLIDSESPYANEVEKRQEQ 1902
Query: 5583 XXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGK 5404
R L + + F RD E + I +K + + D +
Sbjct: 1903 LRTSWENLLQLLNQREQKLHAAGEIHRFHRDVAEALFRIQDKNAALSQELGRDLNSALAL 1962
Query: 5403 LQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKK 5224
L+KH FE +L A E +L + ++ A I + +V WN+L + + +
Sbjct: 1963 LRKHEGFENDLVALEAQLQVLVEDSVRLQAKYPSNASAIAQQQDKVVAAWNDLKERSTAR 2022
Query: 5223 GAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAH 5044
G +L + + Q F ++ D+ +W S L + +E++ D L+ + I + A
Sbjct: 2023 GDRLAASSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEAR 2082
Query: 5043 NDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLF 4864
D+ + +L+ + H+ A + K + L K+K L +
Sbjct: 2083 EDKFRYLNELSDSMVQTGHYAAADVEEKCAAMLDERQKLHAAWNKKKIMLEQKIDLFCFL 2142
Query: 4863 RDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDM 4684
RD + ++ S++ G+ + VQN I+K I + ++ + +
Sbjct: 2143 RDAKQIDNLSSSQQAALSSSDFGQTVEDVQNKIRKHDEFERLIQTQEEKVSLLQEHGRKL 2202
Query: 4683 IQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKE 4504
I+Q H+ + I+ L + + +K RR L+D+L +++ D EA W++EK+
Sbjct: 2203 IEQRHYDSANIQTILQGVLARRQKVKDLCAVRRYKLEDALLYAKFVRDCAEAKYWINEKQ 2262
Query: 4503 PIV--GSTDYGKDEDSAEAL--LKKHRALLSDLEAFKGTIEDLRKQ-ASQCKYQEQPMGQ 4339
+ + Y + + E + L+KH+A +++ A +G I++++ Q + +
Sbjct: 2263 KKLEADAASYAEVTNLDEKIKKLQKHQAFQAEVAANQGRIQEIQDTGVILLSKQHESSPE 2322
Query: 4338 LGRDCVLALYDYQ----EKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPA---- 4183
+ R + L +Q E R +++ N S D + + D++ V A
Sbjct: 2323 IKRAIEIVLEAWQGLLAELEQRGRGLEEAQDSLEFN-SQLDKIEAWIRDKEMMVQASDTG 2381
Query: 4182 -------AYVKRIEPGTAQQHAQQQ----VNSIGGKQSEIEDKYQRLMMLGETRK----- 4051
A +++++ + Q +N + K + + RK
Sbjct: 2382 RDLEHCNALMRKLDDVDSDMRVDDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYN 2441
Query: 4050 -RKLEEACKGYQLL-----------REANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKK 3907
R+L+ A Y+ L R+ +D A+ I + + + G DL VE L ++
Sbjct: 2442 WRQLQGALNAYRALLGGANEIHVFNRDVDDTADRIAEKSLAMSSTDTGRDLAAVEALIRR 2501
Query: 3906 FDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXX 3727
+ + D+ A + ++ + A L A I +++E+L+ W L
Sbjct: 2502 EEALERDMSAVKQKIDQHETAAEFLIKKYPERGAQHIERKLEELHKSWGNLQALSVKRQS 2561
Query: 3726 QLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGD 3547
L A+ +F DV E W+ + +++ + + H+ + ++ +
Sbjct: 2562 ILNEAYLAHKFVSDVKELELWVNDMIKKMNNTQSPSTINDCETQLELHQERKVEIEGRQE 2621
Query: 3546 KIKSLDEKANRL----RQSHPEAAEQ----IYDLQRELNEQWNRLTSKANNRKEKLLDSY 3391
L ++ +L +Q P+ + + +L + LNE W + R L +++
Sbjct: 2622 AFAGLKQQGEQLSKRPQQQQPDNVRKYLLVLEELHQTLNEAW-------SERARDLTEAH 2674
Query: 3390 DYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFD 3211
Q F + + W+A+ +++ +L + T E LL++H E+ + A
Sbjct: 2675 QLQLFKAQVEQVEIWLANKEAFLNNDDLGDSYTAVERLLKKHDEFEKLL--HADHVDTLQ 2732
Query: 3210 QFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADT 3031
+F N +L A I +L + ++ L + R+ L Q +LQ F R + D
Sbjct: 2733 KFANSILEGEPKDADLIREKLAYILRRKQKLLELSEERKQRLTQSHQLQEFLRSLYEIDR 2792
Query: 3030 WMSAR-EAFLAQEDPSGDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSP 2854
W+ + + L + N++S I+KH FD + + +++ + E LI+ +H+
Sbjct: 2793 WLVQKLQVALDENYREPSNLQSKIQKHAAFDAELLSNSPRVQSVIHEGERLIRGDHFAKD 2852
Query: 2853 AVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTE-KFQIAQEENY 2677
+ ++ + W LK A K+ KL ++ F+R DE NWM E + Q++ E+
Sbjct: 2853 EIAQQVQLLEGDWLKLKGASQTKKDKLQQAYDALAFNRSVDEFNNWMDEVELQLSSEDYG 2912
Query: 2676 RDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQ 2497
+D + +K + EA++ + + + Q + E + R +
Sbjct: 2913 KDLAAVSNLLKKHERLEADVAHHGELADQLKQKDEQFFQAEHFLRHE--IHERATVSIRR 2970
Query: 2496 WDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKK 2317
++ L + + L+++ + F+ +D WL E +++ S+D G L SV+ L KK
Sbjct: 2971 YNTLHEPLGIRRENLEDSLSLQQFLRDAEDELQWLAEKQLVAGSQDLGTSLLSVQGLQKK 3030
Query: 2316 HSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDK 2137
H+ LEA++ + + + + ++ ++ ++ F +Q+ + +L+ + ++ +A RR +
Sbjct: 3031 HNSLEAELTSQEPLIQALLQRGQQMIRDNHFASEQLQYKSELLQKQLVQLRDLAAIRRLR 3090
Query: 2136 LSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQ 1957
L A+ F+ + ++ ++W++EK+ ++SS DYGRD VQ ++K + EL + +P
Sbjct: 3091 LLDAVESQLFYVEANEADAWMREKRPVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPS 3150
Query: 1956 VSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFL 1777
+ V L+ I ++ + Q + + L R RL E + +L
Sbjct: 3151 IEKVAKLATGLIE---RNHFDSSNIAEKNAQVGQEYEDLLRLAKERESRLGECKKLFEYL 3207
Query: 1776 GDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTL 1597
+ EE W+ ++ + S+++GE++ V+ L+ ++F +L ++ RV + +GD L
Sbjct: 3208 RETEELHEWVGDQMAVTASEDYGEDVEHVEQLILAFESFVSNLNANEARVEACLERGDRL 3267
Query: 1596 IHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKE 1417
I N + IK + D+ + E++ + R L + D I EK+
Sbjct: 3268 IQENNPYRSSIKSKRDETKQLWEELKDLVHARQDALAGAKQVHVYDRVADETIQLINEKD 3327
Query: 1416 QQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEK 1237
+ SED+G+DL S+Q L K + F++ L + + + + +L IE
Sbjct: 3328 ASLISEDYGQDLESIQALGRKHQVFESELVGIQGQ-VDSVLAEAAKLGEIYPDAKEHIEV 3386
Query: 1236 RHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTD 1057
+ ++ W +L + AR+ +E A W +T
Sbjct: 3387 KRDETVEAWTDLKEKTAARKNKLSQAEQLQSYFDEYRDLIA--------WINEMLAKITA 3438
Query: 1056 PVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALE 877
P NS+ L + + + + +E F + +++ F +E
Sbjct: 3439 PELANSVAGAELLLASTKDHDTEIRTRDETFAKFAANGQQLIK-------EKHFLAHEVE 3491
Query: 876 DTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEMMEA--GGT 703
D + LQ + + L + + E N + F K A W+++ ++ + G +
Sbjct: 3492 DKIKVLQARHELLKHTLNKRREIYELNLDTQL-FLKDAEILEQWISSREPQLKDTKLGDS 3550
Query: 702 LEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERNLILDNRY---TEHSTVGIAQAWDQL 532
+ + D + R K Q EEK ++R +L+ + E + Q ++L
Sbjct: 3551 IPQVEDLLRRHEDFEKTVAAQ----EEKFQAIKRITMLEQLFRHQLEQEKISKLQEKERL 3606
Query: 531 --DQLAMRMQHNLEQQIQARNQSGVSEE 454
++L Q L++ R ++ E
Sbjct: 3607 EKERLEQLKQRELQRLADERRRAEKQHE 3634
Score = 511 bits (1316), Expect = e-142
Identities = 471/2295 (20%), Positives = 948/2295 (40%), Gaps = 57/2295 (2%)
Frame = -1
Query: 7212 ILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTA 7033
I E AD + +R+Q + Y ++ +Q + LE++ F R+ D+ W+ EK +
Sbjct: 942 INENADSVEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKERMI 1001
Query: 7032 QEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEEL 6853
+ + N + K +K F ++ A +K + +D + + H + I R ++
Sbjct: 1002 KSDEGEGVDNAKRKFEK---FITDLSAASKRVEEIDGAVDTFRRQGHSQLDKIIARQRQI 1058
Query: 6852 HALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEIL 6673
H +W + L+ A + F R CDE W+ EK + + DL V+ L
Sbjct: 1059 HQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVITPDLRTVQAL 1118
Query: 6672 QRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATR 6493
QR+ + +EL + ++N + + + +E D + ++ +V D W ++ +
Sbjct: 1119 QRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQDMWQQVQQRGSDL 1178
Query: 6492 KEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAAL 6313
+ + Q FN A LAWI L++D+ RD+ L +KH D+ A
Sbjct: 1179 RNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDLGDDIRAH 1238
Query: 6312 EGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFL 6133
+ + +++ + +L++ P+ AE + + KA +A+ ++ L + L F
Sbjct: 1239 DTEFVEVIQLGKQLSDGKPNMAETV-AVIERLKAEQDAIHRGWAEKQKWLLQCVDLQMFN 1297
Query: 6132 ADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKL 5953
+ + + +A + + L + EA+L+ H + + + A+ + KL
Sbjct: 1298 READKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLDFEKSLMAQDKILKGFSDNADKL 1357
Query: 5952 VEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQE 5773
+ +S + ++ ++ ++ ++ ER+ L + D F + + + W+ +
Sbjct: 1358 ISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKT 1417
Query: 5772 AFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEX 5593
+ + D L ++ ++KH+ FE+ L A E ++ + + L+Q + +V
Sbjct: 1418 RIAGDENYRD-LSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQAGN-RVPEVESR 1475
Query: 5592 XXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARD-DSYLDPTN 5416
+G L+++ ++ +R ++ + E S R D D +
Sbjct: 1476 VADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDSALRSGDVGNDLRS 1535
Query: 5415 IRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDA 5236
+ + K E E+ + ++ ++ STG+ + GHF A +I +++ + +L D
Sbjct: 1536 CKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQQRFKDLRDP 1595
Query: 5235 TNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESD 5056
T ++ AKL E+ N +F ++ W++E S + G++L Q+L KK +E++
Sbjct: 1596 TQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKSNELGQNLHQAQSLHKKHKKLEAE 1655
Query: 5055 FNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQG 4876
H ++ Q ++H + + L+Q + L +R RKL S +
Sbjct: 1656 IKGHQPMINKALVAGQSLISQQHPEREQVESLCQQLEQAWQDLERHCGERSRKLDMSLKA 1715
Query: 4875 NQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSA 4696
Q D + +W+ E+ V ST GRD L+ K + + E+ + + + +
Sbjct: 1716 QQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLLTKHKTIELELDTYSGIVTEMGHS 1775
Query: 4695 ANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWM 4516
M+ H + + K + + L A +R+ L +SL H+Y +++E + W+
Sbjct: 1776 CAAMVAANHPDSKVLAAKQQLIEKMLKSLHKLASQRQGRLMESLYKHEYFLESDEVEQWI 1835
Query: 4515 SEKEPIVGSTDYGKDEDSAEALLK-----KHRA----------------LLSDLEAFKGT 4399
E+E S DYG+D + + L KHR L+ +
Sbjct: 1836 REQEQAASSEDYGQDFEHLQLLQNKFDDLKHRVEVGADRVDQCELLAKKLIDSESPYANE 1895
Query: 4398 IEDLRKQ--------ASQCKYQEQPMGQLG------RDCVLALYDYQEKSPREVSMKKGD 4261
+E ++Q +EQ + G RD AL+ Q+K+ +S + G
Sbjct: 1896 VEKRQEQLRTSWENLLQLLNQREQKLHAAGEIHRFHRDVAEALFRIQDKN-AALSQELGR 1954
Query: 4260 VLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIEPGTAQQHAQQQVNSIGGKQSEIEDKYQ 4081
L A R E ND V + Q ++I +Q ++ +
Sbjct: 1955 DLNSALALLRKHEGFE-NDLVALEAQLQVLVEDSVRLQAKYPSNASAIAQQQDKVVAAWN 2013
Query: 4080 RLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFD 3901
L R +L + L + D+ W + A +E +D L+ + D
Sbjct: 2014 DLKERSTARGDRLAASSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHD 2073
Query: 3900 DFKGDLKANEVRLQEMNQIATALTSVGQ------TETAVRIRQQIEDLNARWRALXXXXX 3739
G+++A E + + +N+++ ++ G E + + + L+A W
Sbjct: 2074 AIYGEIEAREDKFRYLNELSDSMVQTGHYAAADVEEKCAAMLDERQKLHAAWN------- 2126
Query: 3738 XXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLA 3559
L ++ F RD + + + AL S DFG+ + VQ RKH+ ER +
Sbjct: 2127 KKKIMLEQKIDLFCFLRDAKQIDNLSSSQQAALSSSDFGQTVEDVQNKIRKHDEFERLIQ 2186
Query: 3558 ALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQR 3379
+K+ L E +L + + I + + + + ++ R+ KL D+ Y +
Sbjct: 2187 TQEEKVSLLQEHGRKLIEQRHYDSANIQTILQGVLARRQKVKDLCAVRRYKLEDALLYAK 2246
Query: 3378 FLSDYRDLMQWI-ASMNQLVSSQELANDVTGAE---ALLERHQEYRTEIDSRAATFQAFD 3211
F+ D + WI +L + +VT + L++HQ ++ E+ + Q
Sbjct: 2247 FVRDCAEAKYWINEKQKKLEADAASYAEVTNLDEKIKKLQKHQAFQAEVAANQGRIQEIQ 2306
Query: 3210 QFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADT 3031
G LL+ H ++ +I+ ++ V EA +GL R L++ + F ++ +
Sbjct: 2307 DTGVILLSKQHESSPEIKRAIEIVLEAWQGLLAELEQRGRGLEEAQDSLEFNSQLDKIEA 2366
Query: 3030 WMSAREAFLAQEDPSGD--NVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHY-- 2863
W+ +E + D D + +L++K +D D + ++++K + A+ LI
Sbjct: 2367 WIRDKEMMVQASDTGRDLEHCNALMRKLDDVDSDMRVDDQRVKHINQLADKLINQAQVPA 2426
Query: 2862 DSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEK-FQIAQE 2686
D+ +V ++R W L+ AL R LG + + F+RD D+ + + EK ++
Sbjct: 2427 DTQSVDKRRKDFNYNWRQLQGALNAYRALLGGANEIHVFNRDVDDTADRIAEKSLAMSST 2486
Query: 2685 ENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKAL 2506
+ RD ++ ++++A E ++ A +I A LI+ G + + +L+ L
Sbjct: 2487 DTGRDLAAVEALIRREEALERDMSAVKQKIDQHETAAEFLIKKYPERGAQ-HIERKLEEL 2545
Query: 2505 NDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENL 2326
+ W L + ++ L EA F++ VK+LE W+ ++ + + + E
Sbjct: 2546 HKSWGNLQALSVKRQSILNEAYLAHKFVSDVKELELWVNDMIKKMNNTQSPSTINDCETQ 2605
Query: 2325 LKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADR-YDGVKKMATD 2149
L+ H + +I Q+ + +Q + L + Q Q + L+ + + + + ++
Sbjct: 2606 LELHQERKVEIEGRQEAFAGLKQQGEQLSKRPQQQQPDNVRKYLLVLEELHQTLNEAWSE 2665
Query: 2148 RRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELAS 1969
R L++A + F ++ E W+ K+ +++DD G V+ L +KH + L
Sbjct: 2666 RARDLTEAHQLQLFKAQVEQVEIWLANKEAFLNNDDLGDSYTAVERLLKKHDEFEKLL-- 2723
Query: 1968 HEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAF 1789
H V ++ +L + D I++++ + + ++ +L+ R QRL +S
Sbjct: 2724 HADHVDTLQKFANSILEGEPK---DADLIREKLAYILRRKQKLLELSEERKQRLTQSHQL 2780
Query: 1788 QAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINK 1609
Q FL + E + W+ +K Q+ +N+ E + +Q ++KH F +L + RV +I++
Sbjct: 2781 QEFLRSLYEIDRWLVQKLQVALDENYRE-PSNLQSKIQKHAAFDAELLSNSPRVQSVIHE 2839
Query: 1608 GDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWI 1429
G+ LI + I Q+ L ++++ ++ + KL+ L F D +W+
Sbjct: 2840 GERLIRGDHFAKDEIAQQVQLLEGDWLKLKGASQTKKDKLQQAYDALAFNRSVDEFNNWM 2899
Query: 1428 AEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSP 1249
E E Q+ SED+G+DL++V LL K E +A + A E ++ + +Q +EH
Sbjct: 2900 DEVELQLSSEDYGKDLAAVSNLLKKHERLEADV-AHHGELADQLKQKDEQFFQAEHFLRH 2958
Query: 1248 AIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEE 1069
I +R T I+R+ L RR F + A W +
Sbjct: 2959 EIHERATVSIRRYNTLHEPLGIRRENLEDSLSLQ--------QFLRDAEDELQWLAEKQL 3010
Query: 1068 DLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTM 889
SL ++ L+ H + L+S E + L +++ N + +
Sbjct: 3011 VAGSQDLGTSLLSVQGLQKKHNSLEAELTSQEPLIQALLQRGQQMIRDNHFASEQLQYKS 3070
Query: 888 DALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEMMEAG 709
+ L+ L+ + R L + Q F AN AW+ R + +
Sbjct: 3071 ELLQKQLVQLRDLAAIRRLRLLDAVESQ--------LFYVEANEADAWMREKRPVLSSSD 3122
Query: 708 -GTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERNLILDNRYTE----HSTVGIAQA 544
G E + ++K + ++ + EK A L LI N + + Q
Sbjct: 3123 YGRDEVSVQGHQKKLEVLQRELTAFKPSIEKVAKLATGLIERNHFDSSNIAEKNAQVGQE 3182
Query: 543 WDQLDQLAMRMQHNL 499
++ L +LA + L
Sbjct: 3183 YEDLLRLAKERESRL 3197
Score = 503 bits (1294), Expect = e-140
Identities = 491/2306 (21%), Positives = 986/2306 (42%), Gaps = 133/2306 (5%)
Frame = -1
Query: 7119 RLEEARQFQY-FKRDADELNVWILEKLQTAQEENFRDPSNLQAKIQKHEAFEAEVQAHAK 6943
R E+ Q Y F++ + ++ E +Q + + + A ++KHEA A++ A +
Sbjct: 390 RQEKLEQLNYKFEKKSVLREGYLKEMIQVLSDPRYL--RQVDATLKKHEAISADILARVE 447
Query: 6942 TIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQ 6763
+L + + N+ E +++R +E+ A W + + L Q L++ +R+
Sbjct: 448 RFNDLTAMAEELDRENYHGKERVRRREQEVMAKWRQLLELLENQRLNLSQMSNLMNLLRE 507
Query: 6762 CDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQY--RINEINQAADKL 6589
+RE + +ED+G L VE L + L+EL + Y + N+ A
Sbjct: 508 IASTTEAVRELQQQFASEDVGPHLLGVEELLQAHS--LQELQVNTYGETLKRFNRQALPY 565
Query: 6588 VEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKD 6409
H + + ++ D+ +A+ L +A R+ L A F D D +W+ +K
Sbjct: 566 KSSEHKDAALLAQRLADLEEAYSELLRRSAARRARLEEARNFHHFMEDYDNEESWLVDKQ 625
Query: 6408 LALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKL-AETHPDRAEAIHQ 6232
+ +DL V +LQ+KH+ E ++ + + K Q+ +L E HP R+ I
Sbjct: 626 RICKTGITAKDLRAVLSLQQKHKALEDEIKSRKPKSGQMSTAGKRLIGEQHP-RSSEIQS 684
Query: 6231 KNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVA 6052
+ D W AL+ + R+ LE + + ++F D + SW+ + A++ + + D
Sbjct: 685 RIDSLAEHWQALEALVELRRRQLEDAAEAYQFYTDANEAESWLNEKIALVNSRDYGNDEP 744
Query: 6051 GAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGI---------PESPEVQEK---- 5911
A+ALL+ H++ +GE++A + KL++ GI PE PEV+++
Sbjct: 745 SAQALLQRHRDLQGELNAYSGDILNLNQQADKLIKAGICTLELSAAEPELPEVEQEEWVN 804
Query: 5910 --------------LEKLDHEKSSLLGLWEERRILYE---QCMDLQ----LFYRDTEQAE 5794
+EKL+H+K + + + L+ Q M + + + +
Sbjct: 805 ETRLVPKEVWEDEWVEKLEHKKVTETKMLPHVKSLFPFEGQGMKMDKGEVMLLKSKTNDD 864
Query: 5793 TWMNKQEAFLANTDLGDSLDSVE-----------HLIKKHEDFEKSLAAQE----EKINA 5659
W +++ + + + VE +K + +K++ ++ ++I
Sbjct: 865 WWCVRKDNGVEGFVPANYVREVEPRPVACIVPKAEKVKSLQKVKKTILVRQVVPVKRIKP 924
Query: 5658 LDEFATKLIQGQ------HYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFD 5497
+ L+Q + + AD V + R L++S F
Sbjct: 925 VSVAPKPLVQRRTSTQSINENADSVEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFY 984
Query: 5496 RDCDEMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQII 5317
R+CD+ W+ EK + D N + K +K I +L A R+++I +
Sbjct: 985 RECDDFEKWMKEKERMIKSDEGEGVDNAKRKFEKFIT---DLSAASKRVEEIDGAVDTFR 1041
Query: 5316 DSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEG 5137
GH D I R RQ++ +W L +A ++ L A + + FNR ++ + W+SE
Sbjct: 1042 RQGHSQLDKIIARQRQIHQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKML 1101
Query: 5136 QVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQ-----EEEHFNAPV 4972
Q+ + DL +VQ LQ++ +E + D+V+ + L + E+++ NA
Sbjct: 1102 QLDTAVITPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNA-- 1159
Query: 4971 IVRKQE------NLQQRYNALRDPLEKRKRKLGESHQGNQLFRD-IEDELAWIREKEQVA 4813
R+QE +QQR + LR+ + ES G Q+F + + LAWI +
Sbjct: 1160 --RQQEVQDMWQQVQQRGSDLRNRI--------ESEVGQQVFNNSAKVLLAWIDSVKDQL 1209
Query: 4812 GSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLA---PEIRDK 4642
+ RD+ NL+KK L +I HD++ V IQ G L+ P + +
Sbjct: 1210 NADESARDVETANNLLKKHNDLGDDIRAHDTEFVEV-------IQLGKQLSDGKPNMAET 1262
Query: 4641 LAQLR----DNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGK 4474
+A + + I + AEK++ L + + +A++ DA E + + G
Sbjct: 1263 VAVIERLKAEQDAIHRGWAEKQKW-LLQCVDLQMFNREADKIDATTKSHEAFLEYNNLGA 1321
Query: 4473 DEDSAEALLKKH----RALLSDLEAFKGTIEDLRKQASQCKYQEQPMGQLGRDCVL---- 4318
D EA+LK+H ++L++ + KG ++ K S Y + +G R+ VL
Sbjct: 1322 SLDEVEAILKRHLDFEKSLMAQDKILKGFSDNADKLISNDHYDSKYIGD-RRNQVLGKRK 1380
Query: 4317 ALYDYQEKSPREVSMKKGDVLTLLNASNRDWW---KVEVNDRQGFVPAAYVKR------- 4168
A+ D + R + K A + W K + + + + + R
Sbjct: 1381 AVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKTRIAGDENYRDLSNLPRKLQKHQA 1440
Query: 4167 ---------------IEPGTAQQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEA 4033
+ G A A +V + + +++ +++ L+ L E + RKLE+A
Sbjct: 1441 FERELRANEGQLRNVTKDGQALVQAGNRVPEVESRVADLNKRWKDLLTLSEDKGRKLEQA 1500
Query: 4032 CKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEM 3853
+ R D + + ++ ++G DL + L K + ++ + ++ E+
Sbjct: 1501 ASQREHNRSLEDAKKKVDELDSALRSGDVGNDLRSCKDLINKQQILESEITIWDQKVAEL 1560
Query: 3852 NQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDET 3673
+ G A I ++L R++ L +L + +F ++D
Sbjct: 1561 VSTGDDMAHGGHF-NAQNIEAGTKELQQRFKDLRDPTQRRRAKLEESLNYHKFVFELDSE 1619
Query: 3672 RDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKI-KSLDEKANRLRQSHP 3496
WI E A S + G++L Q+L +KH+ +E ++ I K+L + + Q HP
Sbjct: 1620 FQWINEHLPAAKSNELGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALVAGQSLISQQHP 1679
Query: 3495 EAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSS 3316
E EQ+ L ++L + W L R KL S Q++L D ++ W+ N ++ S
Sbjct: 1680 E-REQVESLCQQLEQAWQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERNNVLRS 1738
Query: 3315 QELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVN 3136
E D A LL +H+ E+D+ + ++ ++H + + + Q +
Sbjct: 1739 TEYGRDRDSAAKLLTKHKTIELELDTYSGIVTEMGHSCAAMVAANHPDSKVLAAKQQLIE 1798
Query: 3135 EARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGD--NVESLI 2962
+ K L R+ L + L ++ + ++ + W+ +E + ED D +++ L
Sbjct: 1799 KMLKSLHKLASQRQGRLMESLYKHEYFLESDEVEQWIREQEQAASSEDYGQDFEHLQLLQ 1858
Query: 2961 KKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKR 2782
K +D + +++ +L A+ LI + + V ++++Q+ W L + L Q+
Sbjct: 1859 NKFDDLKHRVEVGADRVDQCELLAKKLIDSESPYANEVEKRQEQLRTSWENLLQLLNQRE 1918
Query: 2781 FKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHANSD 2602
KL + + +F RD E + +K +E RD + +K + FE +L A
Sbjct: 1919 QKLHAAGEIHRFHRDVAEALFRIQDKNAALSQELGRDLNSALALLRKHEGFENDLVALEA 1978
Query: 2601 RIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFM 2422
++ +++ L AK +A++ + + W+ L + +T + RL ++ ++F+
Sbjct: 1979 QLQVLVEDSVRL--QAKYPSNASAIAQQQDKVVAAWNDLKERSTARGDRLAASSDLQTFL 2036
Query: 2421 AAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSL 2242
V+D+ W + LQ+E++ D A L +H + +I A +D+ +NE +DS+
Sbjct: 2037 TDVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEAREDKFRYLNELSDSM 2096
Query: 2241 LENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKK 2062
++ + + E+ + D + ++ L + +++ F RD ++ ++
Sbjct: 2097 VQTGHYAAADVEEKCAAMLDERQKLHAAWNKKKIMLEQKIDLFCFLRDAKQIDNLSSSQQ 2156
Query: 2061 LLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQI 1882
+SS D+G+ + VQN RKH + + + E +VSL++ G +L+ + I
Sbjct: 2157 AALSSSDFGQTVEDVQNKIRKHDEFERLIQTQEEKVSLLQEHGRKLIE---QRHYDSANI 2213
Query: 1881 KKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSD--NFG 1708
+ ++ + +++DL R +L+++ + F+ D E + W+NEKQ+ L +D ++
Sbjct: 2214 QTILQGVLARRQKVKDLCAVRRYKLEDALLYAKFVRDCAEAKYWINEKQKKLEADAASYA 2273
Query: 1707 E--NMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQL--- 1543
E N+ L+KH FQ ++ ++ R+ ++ + G L+ + +P IK+ + +
Sbjct: 2274 EVTNLDEKIKKLQKHQAFQAEVAANQGRIQEIQDTGVILLSKQHESSPEIKRAIEIVLEA 2333
Query: 1542 -RARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQI 1366
+ L E+E G L + L+F + D +E+WI +KE V++ D GRDL
Sbjct: 2334 WQGLLAELEQRGRG----LEEAQDSLEFNSQLDKIEAWIRDKEMMVQASDTGRDLEHCNA 2389
Query: 1365 LLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEH--QQSPAIEKRHTNVIQRWQNLLAH 1192
L+ K + D+ + + + ++ I +L D+L++ + +++KR + W+ L
Sbjct: 2390 LMRKLDDVDSDMRV-DDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYNWRQLQGA 2448
Query: 1191 SEARRX---XXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRA 1021
A R +++ A+K+ +S TD R L + A
Sbjct: 2449 LNAYRALLGGANEIHVFNRDVDDTADRIAEKSLAMSS---------TDTGR--DLAAVEA 2497
Query: 1020 LRDAHGEFQRSLSSAEEDFRQLQD-LDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIK 844
L +R +S+ ++ Q + + IK + + ++ L +W NLQ +
Sbjct: 2498 LIRREEALERDMSAVKQKIDQHETAAEFLIKKYPERGAQHIERKLEELHKSWGNLQALSV 2557
Query: 843 EREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEM--MEAGGTL---EEQLDAV 679
+R+ L + L +F W+ + ++M ++ T+ E QL+
Sbjct: 2558 KRQSILNEAY--------LAHKFVSDVKELELWVNDMIKKMNNTQSPSTINDCETQLELH 2609
Query: 678 ERKAKEIKANKGQLRQIEEKGAMLER 601
+ + EI+ + ++++G L +
Sbjct: 2610 QERKVEIEGRQEAFAGLKQQGEQLSK 2635
Score = 455 bits (1170), Expect = e-126
Identities = 455/2234 (20%), Positives = 916/2234 (40%), Gaps = 59/2234 (2%)
Frame = -1
Query: 7185 QRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQ----EENF 7018
QR ++ YS S +R RLEEAR F +F D D W+++K + + ++
Sbjct: 578 QRLADLEEAYSELLRRSAARRARLEEARNFHHFMEDYDNEESWLVDKQRICKTGITAKDL 637
Query: 7017 RDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWX 6838
R +LQ QKH+A E E+++ + G +I H S I+ R++ L W
Sbjct: 638 RAVLSLQ---QKHKALEDEIKSRKPKSGQMSTAGKRLIGEQHPRSSEIQSRIDSLAEHWQ 694
Query: 6837 XXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFD 6658
+ +L+ A + F +E W+ EK V + D G D + L ++
Sbjct: 695 ALEALVELRRRQLEDAAEAYQFYTDANEAESWLNEKIALVNSRDYGNDEPSAQALLQRHR 754
Query: 6657 DFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLF 6478
D EL + I +NQ ADKL++ G + TL + E
Sbjct: 755 DLQGELNAYSGDILNLNQQADKLIKAG--------------------ICTLELSAAEP-- 792
Query: 6477 GAHQVQRFNRDADETLAWIGEKDLA---LSSDDYGRDLNNVQALQRKHEGTERDLAALEG 6307
E W+ E L + D++ L + + + K + L EG
Sbjct: 793 --------ELPEVEQEEWVNETRLVPKEVWEDEWVEKLEHKKVTETKMLPHVKSLFPFEG 844
Query: 6306 KMLQLEK-EAHKLAETHPDRAEAIHQKND-DTKAAWNALKEKAQHRKDGLERSFQLHRFL 6133
+ ++++K E L D + + N + N ++E + + + L
Sbjct: 845 QGMKMDKGEVMLLKSKTNDDWWCVRKDNGVEGFVPANYVREVEPRPVACIVPKAEKVKSL 904
Query: 6132 ADYRD--LISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQ 5959
+ L+ + +K + K + +S E+ ++ R NQT
Sbjct: 905 QKVKKTILVRQVVPVKRIKPVSVAPKPLVQRRTSTQSINENADSVEKRQQRINQTYD--- 961
Query: 5958 KLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNK 5779
E+QE +K R L E + L FYR+ + E WM +
Sbjct: 962 -----------ELQEMAQK--------------RHALLEDSIHLFGFYRECDDFEKWMKE 996
Query: 5778 QEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVA 5599
+E + +D G+ +D+ + +K E F L+A +++ +D + H D +
Sbjct: 997 KERMI-KSDEGEGVDNAK---RKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDKII 1052
Query: 5598 EXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDP- 5422
R +L+ + + F+R CDE W++EK+ D + + P
Sbjct: 1053 ARQRQIHQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKM-LQLDTAVITPD 1111
Query: 5421 -TNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNEL 5245
++ ++H N E+EL E++++ + G + ++ D++ R ++V ++W ++
Sbjct: 1112 LRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQDMWQQV 1171
Query: 5244 VDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLI 5065
+ ++ +Q FN + + + AW+ ++ Q+ +++ +D+ + NL KK +
Sbjct: 1172 QQRGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDL 1231
Query: 5064 ESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGES 4885
D AH+ + QL +Q + + N V E L+ +A+ ++++ L +
Sbjct: 1232 GDDIRAHDTEFVEVIQLGKQLSDGKP-NMAETVAVIERLKAEQDAIHRGWAEKQKWLLQC 1290
Query: 4884 HQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESV 4705
R+ + A + E N G L V+ ++K+ + D ++
Sbjct: 1291 VDLQMFNREADKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLDFEKSLMAQDKILKGF 1350
Query: 4704 SSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEAD 4525
S A+ +I H+ + I D+ Q+ + +K +A +R+ L S H++ ++A++
Sbjct: 1351 SDNADKLISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEADDLK 1410
Query: 4524 AWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQA---------- 4375
W+ +K I G +Y +D + L+KH+A +L A +G + ++ K
Sbjct: 1411 VWLQDKTRIAGDENY-RDLSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQAGNRV 1469
Query: 4374 --------------------SQCKYQEQPMGQLGRDCVLALYDYQEK-SPREVSMKKGDV 4258
S+ K ++ R+ +L D ++K + +++ GDV
Sbjct: 1470 PEVESRVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDSALRSGDV 1529
Query: 4257 LTLLNASNRDWWKVEVNDRQGFV-PAAYVKRIEPGTAQQHAQQ-QVNSIGGKQSEIEDKY 4084
L + K ++ + + + + + G H +I E++ ++
Sbjct: 1530 GNDLRSCKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQQRF 1589
Query: 4083 QRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKF 3904
+ L + R+ KLEE+ ++ + E + +WI A E+G +L Q + L KK
Sbjct: 1590 KDLRDPTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKSNELGQNLHQAQSLHKKH 1649
Query: 3903 DDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQ 3724
+ ++K ++ + + +L S E ++ + L W+ L +
Sbjct: 1650 KKLEAEIKGHQPMINKALVAGQSLISQQHPERE-QVESLCQQLEQAWQDLERHCGERSRK 1708
Query: 3723 LGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDK 3544
L + + Q++ D E W+ E+++ L S ++GRD S L KH+ +E +L
Sbjct: 1709 LDMSLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLLTKHKTIELELDTYSGI 1768
Query: 3543 IKSLDEK-ANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSD 3367
+ + A + +HP+ ++ + Q+ + + L A+ R+ +L++S + +
Sbjct: 1769 VTEMGHSCAAMVAANHPD-SKVLAAKQQLIEKMLKSLHKLASQRQGRLMESLYKHEYFLE 1827
Query: 3366 YRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLN 3187
++ QWI Q SS++ D + L + + + ++ A + +L++
Sbjct: 1828 SDEVEQWIREQEQAASSEDYGQDFEHLQLLQNKFDDLKHRVEVGADRVDQCELLAKKLID 1887
Query: 3186 SHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAF 3007
S A ++E R + + + + L R L E+ F+RD +A + + A
Sbjct: 1888 SESPYANEVEKRQEQLRTSWENLLQLLNQREQKLHAAGEIHRFHRDVAEALFRIQDKNAA 1947
Query: 3006 LAQE-DPSGDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQ 2830
L+QE ++ +L++KHE F+ + E +++ L + L ++ A+ +++D+
Sbjct: 1948 LSQELGRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSVRLQAKYPSNASAIAQQQDK 2007
Query: 2829 ILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTE-KFQIAQEENYRDPTNIQQ 2653
++ WN LKE + +L S LQ F D +I +W + + + EE+ D
Sbjct: 2008 VVAAWNDLKERSTARGDRLAASSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAGATA 2067
Query: 2652 KHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTT 2473
+ A E+ A D+ + + +++++ A V + A+ D+ L
Sbjct: 2068 LKIQHDAIYGEIEAREDKFRYLNELSDSMVQTGHYAA--ADVEEKCAAMLDERQKLHAAW 2125
Query: 2472 TEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADI 2293
+K L++ F+ K ++ + L S D+G+ + V+N ++KH E I
Sbjct: 2126 NKKKIMLEQKIDLFCFLRDAKQIDNLSSSQQAALSSSDFGQTVEDVQNKIRKHDEFERLI 2185
Query: 2292 VAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVH 2113
+++V + E L+E + I + + R VK + RR KL AL
Sbjct: 2186 QTQEEKVSLLQEHGRKLIEQRHYDSANIQTILQGVLARRQKVKDLCAVRRYKLEDALLYA 2245
Query: 2112 QFFRDIDDEESWI--KEKKLLVSSDDYGRDLPGVQNLRR--KHRRIDTELASHEPQVSLV 1945
+F RD + + WI K+KKL + Y + +++ KH+ E+A+++ ++ +
Sbjct: 2246 KFVRDCAEAKYWINEKQKKLEADAASYAEVTNLDEKIKKLQKHQAFQAEVAANQGRIQEI 2305
Query: 1944 KLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVE 1765
+ G LL E+ +IK+ +E + ++W + R + L+E++ F ++
Sbjct: 2306 QDTGVILLSKQHES---SPEIKRAIEIVLEAWQGLLAELEQRGRGLEEAQDSLEFNSQLD 2362
Query: 1764 EEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNG 1585
+ EAW+ +K+ ++ + + G ++ L++K D D+ + QRV + D LI+
Sbjct: 2363 KIEAWIRDKEMMVQASDTGRDLEHCNALMRKLDDVDSDMRVDDQRVKHINQLADKLINQA 2422
Query: 1584 NHHA--PHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQ 1411
A + +R +++ A L + F D IAEK
Sbjct: 2423 QVPADTQSVDKRRKDFNYNWRQLQGALNAYRALLGGANEIHVFNRDVDDTADRIAEKSLA 2482
Query: 1410 VRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRH 1231
+ S D GRDL++V+ L+ ++EA + ++A + + Q T + + + + IE++
Sbjct: 2483 MSSTDTGRDLAAVEALIRREEALERDMSAVKQKIDQHETAAEFLIKKYPERGAQHIERKL 2542
Query: 1230 TNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLA--FAKKASTFNSWFENAEEDLTD 1057
+ + W NL A S R+ + E YLA F W + + + +
Sbjct: 2543 EELHKSWGNLQALSVKRQ----------SILNEAYLAHKFVSDVKELELWVNDMIKKMNN 2592
Query: 1056 PVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRI--KSFNVGPNPYTWFTMDA 883
+++ + + H E + + +E F L+ ++ + P+ + +
Sbjct: 2593 TQSPSTINDCETQLELHQERKVEIEGRQEAFAGLKQQGEQLSKRPQQQQPDNVRKYLL-V 2651
Query: 882 LEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEMMEAGGT 703
LE+ + L ER ++L HQ Q F WL N +E
Sbjct: 2652 LEELHQTLNEAWSERARDLTEAHQLQ--------LFKAQVEQVEIWLAN--KEAFLNNDD 2701
Query: 702 LEEQLDAVERKAKE 661
L + AVER K+
Sbjct: 2702 LGDSYTAVERLLKK 2715
Score = 328 bits (840), Expect = 2e-87
Identities = 188/525 (35%), Positives = 297/525 (55%), Gaps = 2/525 (0%)
Frame = -1
Query: 7224 QEIRILETADDIHQRRQEVLGHYSI-FKDHSQTKRDRLEEARQFQYFKRDADELNVWILE 7048
Q IR A + Q + E+L + +D + +R RL +A + Q F +A+E + W+ E
Sbjct: 3054 QMIRDNHFASEQLQYKSELLQKQLVQLRDLAAIRRLRLLDAVESQLFYVEANEADAWMRE 3113
Query: 7047 KLQTAQEENF-RDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIK 6871
K ++ RD ++Q +K E + E+ A +I + K +I+ NHF S +I
Sbjct: 3114 KRPVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPSIEKVAKLATGLIERNHFDSSNIA 3173
Query: 6870 KRLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDL 6691
++ ++ + + +L + KL ++R+ +E+ W+ ++ +ED G D+
Sbjct: 3174 EKNAQVGQEYEDLLRLAKERESRLGECKKLFEYLRETEELHEWVGDQMAVTASEDYGEDV 3233
Query: 6690 EHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLN 6511
EHVE L F+ F+ L ++ R+ + D+L++E + I KRD+ W L
Sbjct: 3234 EHVEQLILAFESFVSNLNANEARVEACLERGDRLIQENNPYRSSIKSKRDETKQLWEELK 3293
Query: 6510 TLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTE 6331
L R++ L GA QV ++R ADET+ I EKD +L S+DYG+DL ++QAL RKH+ E
Sbjct: 3294 DLVHARQDALAGAKQVHVYDRVADETIQLINEKDASLISEDYGQDLESIQALGRKHQVFE 3353
Query: 6330 RDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSF 6151
+L ++G++ + EA KL E +PD E I K D+T AW LKEK RK+ L ++
Sbjct: 3354 SELVGIQGQVDSVLAEAAKLGEIYPDAKEHIEVKRDETVEAWTDLKEKTAARKNKLSQAE 3413
Query: 6150 QLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTA 5971
QL + +YRDLI+WI +M A I A ELA VAGAE LL S ++H EI R ++F + A
Sbjct: 3414 QLQSYFDEYRDLIAWINEMLAKITAPELANSVAGAELLLASTKDHDTEIRTRDETFAKFA 3473
Query: 5970 SAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAET 5791
+ GQ+L++ + EV++K++ L L +RR +YE +D QLF +D E E
Sbjct: 3474 ANGQQLIKEKHFLAHEVEDKIKVLQARHELLKHTLNKRREIYELNLDTQLFLKDAEILEQ 3533
Query: 5790 WMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINAL 5656
W++ +E L +T LGDS+ VE L+++HEDFEK++AAQEEK A+
Sbjct: 3534 WISSREPQLKDTKLGDSIPQVEDLLRRHEDFEKTVAAQEEKFQAI 3578
Score = 313 bits (802), Expect = 4e-83
Identities = 227/909 (24%), Positives = 428/909 (46%), Gaps = 5/909 (0%)
Frame = -1
Query: 7200 ADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEEN 7021
AD I ++ +L + S+ ++ RL ++ Q Q F R E++ W+++KLQ A +EN
Sbjct: 2746 ADLIREKLAYILRRKQKLLELSEERKQRLTQSHQLQEFLRSLYEIDRWLVQKLQVALDEN 2805
Query: 7020 FRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALW 6841
+R+PSNLQ+KIQKH AF+AE+ +++ + ++ G +I+ +HFA + I ++++ L W
Sbjct: 2806 YREPSNLQSKIQKHAAFDAELLSNSPRVQSVIHEGERLIRGDHFAKDEIAQQVQLLEGDW 2865
Query: 6840 XXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKF 6661
K KLQQA L F R DE W+ E E +++ED G DL V L +K
Sbjct: 2866 LKLKGASQTKKDKLQQAYDALAFNRSVDEFNNWMDEVELQLSSEDYGKDLAAVSNLLKKH 2925
Query: 6660 DDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGL 6481
+ ++ +H +++ Q ++ + H +I+++ ++ L+ R+E L
Sbjct: 2926 ERLEADVAHHGELADQLKQKDEQFFQAEHFLRHEIHERATVSIRRYNTLHEPLGIRRENL 2985
Query: 6480 FGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKM 6301
+ +Q+F RDA++ L W+ EK L S D G L +VQ LQ+KH E +L + E +
Sbjct: 2986 EDSLSLQQFLRDAEDELQWLAEKQLVAGSQDLGTSLLSVQGLQKKHNSLEAELTSQEPLI 3045
Query: 6300 LQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYR 6121
L + ++ + +E + K++ + L++ A R+ L + + F +
Sbjct: 3046 QALLQRGQQMIRDNHFASEQLQYKSELLQKQLVQLRDLAAIRRLRLLDAVESQLFYVEAN 3105
Query: 6120 DLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMG 5941
+ +W+ + + V+ + + +D + + + + E+ A S + A L+E
Sbjct: 3106 EADAWMREKRPVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPSIEKVAKLATGLIERN 3165
Query: 5940 IPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLA 5761
+S + EK ++ E LL L +ER +C L + R+TE+ W+ Q A A
Sbjct: 3166 HFDSSNIAEKNAQVGQEYEDLLRLAKERESRLGECKKLFEYLRETEELHEWVGDQMAVTA 3225
Query: 5760 NTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXX 5581
+ D G+ ++ VE LI E F +L A E ++ A E +LIQ + +
Sbjct: 3226 SEDYGEDVEHVEQLILAFESFVSNLNANEARVEACLERGDRLIQENNPYRSSIKSKRDET 3285
Query: 5580 XXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEK-LSTARDDSYLDPTNIRGK 5404
R +AL + + +DR DE + I EK S +D D +I+
Sbjct: 3286 KQLWEELKDLVHARQDALAGAKQVHVYDRVADETIQLINEKDASLISEDYGQDLESIQAL 3345
Query: 5403 LQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKK 5224
+KH FE EL + ++D + + ++ + A +HI + + W +L + T +
Sbjct: 3346 GRKHQVFESELVGIQGQVDSVLAEAAKLGEIYPDAKEHIEVKRDETVEAWTDLKEKTAAR 3405
Query: 5223 GAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAH 5044
KL +A Q + D+ AW++E+ ++ + + + + L +++
Sbjct: 3406 KNKLSQAEQLQSYFDEYRDLIAWINEMLAKITAPELANSVAGAELLLASTKDHDTEIRTR 3465
Query: 5043 NDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLF 4864
++ QQ +E+HF A + K + LQ R+ L+ L KR R++ E + QLF
Sbjct: 3466 DETFAKFAANGQQLIKEKHFLAHEVEDKIKVLQARHELLKHTLNKR-REIYELNLDTQLF 3524
Query: 4863 -RDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAAND 4687
+D E WI +E T G + V++L+++ + +A + + +++
Sbjct: 3525 LKDAEILEQWISSREPQLKDTKLGDSIPQVEDLLRRHEDFEKTVAAQEEKFQAIKRIT-- 3582
Query: 4686 MIQQGHFLAPEIRDKLAQLRDNWRILKSKAEK-RRTDLDDSLQAHQYLSDANE--ADAWM 4516
M++Q F ++K+++L++ R+ K + E+ ++ +L + +E +A
Sbjct: 3583 MLEQ-LFRHQLEQEKISKLQEKERLEKERLEQLKQRELQRLADERRRAEKQHEHRQNAAS 3641
Query: 4515 SEKEPIVGS 4489
EK PI S
Sbjct: 3642 QEKTPIFSS 3650
Score = 219 bits (557), Expect = 1e-54
Identities = 252/1272 (19%), Positives = 506/1272 (38%), Gaps = 86/1272 (6%)
Frame = -1
Query: 3999 DLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQ-----IATA 3835
+L WI+ + Q+++ LE ++ F +++ K + + + + I T
Sbjct: 287 NLLSWIRQKTLELEQRDLPNSLEGIQRELLAFKEYRTIEKPPKYKERSEIEALYFTINTL 346
Query: 3834 LTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQ--------RFHRDVD 3679
L ++ Q + Q + D+ W+ L L Q +F +
Sbjct: 347 LKALNQPPYNPQDGQLVNDIEKAWQILEYAEHHREVALRDELLRQEKLEQLNYKFEKKSV 406
Query: 3678 ETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSH 3499
+++E L R LR V A +KHE + D+ A ++ L A L + +
Sbjct: 407 LREGYLKEMIQVLSDP---RYLRQVDATLKKHEAISADILARVERFNDLTAMAEELDREN 463
Query: 3498 PEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVS 3319
E++ ++E+ +W +L N++ L + L + + + + Q +
Sbjct: 464 YHGKERVRRREQEVMAKWRQLLELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQFA 523
Query: 3318 SQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGV 3139
S+++ + G E LL+ H ++++ T + F++ +S H A + RL +
Sbjct: 524 SEDVGPHLLGVEELLQAHSLQELQVNTYGETLKRFNRQALPYKSSEHKDAALLAQRLADL 583
Query: 3138 NEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGD--NVESL 2965
EA L ARR L++ F D + ++W+ ++ + D V SL
Sbjct: 584 EEAYSELLRRSAARRARLEEARNFHHFMEDYDNEESWLVDKQRICKTGITAKDLRAVLSL 643
Query: 2964 IKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQK 2785
+KH+ + I +++ K + + LI H S + + D + + W L+ + +
Sbjct: 644 QQKHKALEDEIKSRKPKSGQMSTAGKRLIGEQHPRSSEIQSRIDSLAEHWQALEALVELR 703
Query: 2784 RFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENY-RDPTNIQQKHQKQQAFEAELHAN 2608
R +L ++ QF DA+E E+W+ EK + +Y D + Q Q+ + + EL+A
Sbjct: 704 RRQLEDAAEAYQFYTDANEAESWLNEKIALVNSRDYGNDEPSAQALLQRHRDLQGELNAY 763
Query: 2607 SDRIAAIIQAGNNLIENAKCGGGEAAVSARL-----------------KALNDQW----- 2494
S I + Q + LI+ C +A L + D+W
Sbjct: 764 SGDILNLNQQADKLIKAGICTLELSAAEPELPEVEQEEWVNETRLVPKEVWEDEWVEKLE 823
Query: 2493 -------------------------------DLLVKTTTEKSYRLKEANKQKSFMAAVKD 2407
LL T + + +++ N + F+ A
Sbjct: 824 HKKVTETKMLPHVKSLFPFEGQGMKMDKGEVMLLKSKTNDDWWCVRKDNGVEGFVPANYV 883
Query: 2406 LEFWLGEVEILLQSEDYGKDLASVENLL-----------KKHSLLEADIVAHQDRVGEMN 2260
E V ++ + K L V+ + K S+ +V + +N
Sbjct: 884 REVEPRPVACIVPKAEKVKSLQKVKKTILVRQVVPVKRIKPVSVAPKPLVQRRTSTQSIN 943
Query: 2259 EQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEES 2080
E ADS + +R++ I YD +++MA R L ++++ F+R+ DD E
Sbjct: 944 ENADS-----------VEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEK 992
Query: 2079 WIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAG 1900
W+KEK+ ++ SD+ GV N +RK + T+L++ +V + + R
Sbjct: 993 WMKEKERMIKSDEG----EGVDNAKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQ- 1047
Query: 1899 VGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGS 1720
D+I R + Q W ++ + R + L+ + + + F +E + WM+EK L +
Sbjct: 1048 --LDKIIARQRQIHQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDT 1105
Query: 1719 DNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLR 1540
++ VQ L ++H + +L + +V + G+++ + ++ R +++
Sbjct: 1106 AVITPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQ 1165
Query: 1539 ARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILL 1360
+++ ++ F V+ +WI + Q+ +++ RD+ + LL
Sbjct: 1166 DMWQQVQQRGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLL 1225
Query: 1359 TKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEAR 1180
K + A + E ++ + +L QL + + + VI+R L A +A
Sbjct: 1226 KKHNDLGDDIRAHDTEFVE-VIQLGKQLSDGKPNMAETVA-----VIER---LKAEQDAI 1276
Query: 1179 RXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGE 1000
Q +L + F ++A ++ ++ E L SL+E+ A+ H +
Sbjct: 1277 HRGWAEKQKWLLQCVDLQM-FNREADKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLD 1335
Query: 999 FQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAR 820
F++SL + ++ + D ++ S + + Y + + ++ +K+R A
Sbjct: 1336 FEKSLMAQDKILKGFSDNADKLISNDHYDSKY----IGDRRNQVLGKRKAVKDR----AF 1387
Query: 819 EHQRQEENDKLRREFAKLANAFHAWLTN-TR---QEMMEAGGTLEEQLDAVERKAKEIKA 652
E +R + K +FA A+ WL + TR E L +L + +E++A
Sbjct: 1388 ERKRLLQASKDFHKFAAEADDLKVWLQDKTRIAGDENYRDLSNLPRKLQKHQAFERELRA 1447
Query: 651 NKGQLRQIEEKGAMLERNLILDNRY--TEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQAR 478
N+GQLR + + G L + NR E + + W L L+ LEQ R
Sbjct: 1448 NEGQLRNVTKDGQALVQ---AGNRVPEVESRVADLNKRWKDLLTLSEDKGRKLEQAASQR 1504
Query: 477 NQSGVSEEALRE 442
+ E+A ++
Sbjct: 1505 EHNRSLEDAKKK 1516
Score = 145 bits (366), Expect = 1e-32
Identities = 99/418 (23%), Positives = 192/418 (45%)
Frame = -1
Query: 2838 RDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNI 2659
RD++L + E L Q +K + L+ E ++ E Q+ + Y +
Sbjct: 385 RDELLRQ-----EKLEQLNYKFEKKSVLR---------EGYLKEMIQVLSDPRYLRQVDA 430
Query: 2658 QQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVK 2479
K K +A A++ A +R + L + + G+ V R + + +W L++
Sbjct: 431 TLK--KHEAISADILARVERFNDLTAMAEEL--DRENYHGKERVRRREQEVMAKWRQLLE 486
Query: 2478 TTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEA 2299
+ L + + + + + + E++ SED G L VE LL+ HSL E
Sbjct: 487 LLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQFASEDVGPHLLGVEELLQAHSLQEL 546
Query: 2298 DIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALN 2119
+ + + + N QA ++ +A+R + + Y + + + RR +L +A N
Sbjct: 547 QVNTYGETLKRFNRQALPYKSSEHKDAALLAQRLADLEEAYSELLRRSAARRARLEEARN 606
Query: 2118 VHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKL 1939
H F D D+EESW+ +K+ + + +DL V +L++KH+ ++ E+ S +P+ +
Sbjct: 607 FHHFMEDYDNEESWLVDKQRICKTGITAKDLRAVLSLQQKHKALEDEIKSRKPKSGQMST 666
Query: 1938 KGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEE 1759
G+ L+ E +I+ R++ L + W + L R ++L+++ F D E
Sbjct: 667 AGKRLI---GEQHPRSSEIQSRIDSLAEHWQALEALVELRRRQLEDAAEAYQFYTDANEA 723
Query: 1758 EAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNG 1585
E+W+NEK ++ S ++G + Q LL++H Q +L + + +L + D LI G
Sbjct: 724 ESWLNEKIALVNSRDYGNDEPSAQALLQRHRDLQGELNAYSGDILNLNQQADKLIKAG 781
Score = 137 bits (344), Expect = 5e-30
Identities = 120/502 (23%), Positives = 222/502 (43%), Gaps = 20/502 (3%)
Frame = -1
Query: 3360 DLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRT-----------EIDSRAATFQAF 3214
+L+ WI + ++L N + G + L +EYRT EI++ T
Sbjct: 287 NLLSWIRQKTLELEQRDLPNSLEGIQRELLAFKEYRTIEKPPKYKERSEIEALYFTINTL 346
Query: 3213 DQFGNQLLNSHH--YAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQ 3040
+ NQ + DIE Q + A E A R +L Q QL Y+ ++
Sbjct: 347 LKALNQPPYNPQDGQLVNDIEKAWQILEYAEHHREVA--LRDELLRQEKLEQLNYKFEKK 404
Query: 3039 ADTWMSAREAFLAQ-----EDPSG-DNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLI 2878
+ RE +L + DP V++ +KKHE I + E+ L AE L
Sbjct: 405 S----VLREGYLKEMIQVLSDPRYLRQVDATLKKHEAISADILARVERFNDLTAMAEELD 460
Query: 2877 KNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTE-KF 2701
+ N++ V R+ +++ +W L E L +R L + L R+ + E +
Sbjct: 461 RENYHGKERVRRREQEVMAKWRQLLELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQ 520
Query: 2700 QIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSA 2521
Q A E+ +++ Q E +++ + + + L + A ++
Sbjct: 521 QFASEDVGPHLLGVEELLQAHSLQELQVNTYGETLKRFNRQA--LPYKSSEHKDAALLAQ 578
Query: 2520 RLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLA 2341
RL L + + L++ + + RL+EA FM + E WL + + + ++ KDL
Sbjct: 579 RLADLEEAYSELLRRSAARRARLEEARNFHHFMEDYDNEESWLVDKQRICKTGITAKDLR 638
Query: 2340 SVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKK 2161
+V +L +KH LE +I + + + G+M+ L+ + +I R +A+ + ++
Sbjct: 639 AVLSLQQKHKALEDEIKSRKPKSGQMSTAGKRLIGEQHPRSSEIQSRIDSLAEHWQALEA 698
Query: 2160 MATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDT 1981
+ RR +L A +QF+ D ++ ESW+ EK LV+S DYG D P Q L ++HR +
Sbjct: 699 LVELRRRQLEDAAEAYQFYTDANEAESWLNEKIALVNSRDYGNDEPSAQALLQRHRDLQG 758
Query: 1980 ELASHEPQVSLVKLKGEELLRS 1915
EL ++ + + + ++L+++
Sbjct: 759 ELNAYSGDILNLNQQADKLIKA 780
Score = 95.9 bits (237), Expect = 1e-17
Identities = 92/499 (18%), Positives = 195/499 (38%), Gaps = 17/499 (3%)
Frame = -1
Query: 6753 ILYWIREKETYVTAEDMGMDLEHVEILQRKFDDF--------LKELGNHQYRINEINQAA 6598
+L WIR+K + D+ LE ++ F ++ KE + IN
Sbjct: 288 LLSWIRQKTLELEQRDLPNSLEGIQRELLAFKEYRTIEKPPKYKERSEIEALYFTINTLL 347
Query: 6597 DKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATR----KEGLFGAHQVQRFNRDADETL 6430
L + ++ D + +D+ AW L R ++ L ++++ N ++
Sbjct: 348 KALNQPPYNPQDG--QLVNDIEKAWQILEYAEHHREVALRDELLRQEKLEQLNYKFEKKS 405
Query: 6429 A----WIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAET 6262
++ E LS Y L V A +KHE D+ A + L A +L
Sbjct: 406 VLREGYLKEMIQVLSDPRY---LRQVDATLKKHEAISADILARVERFNDLTAMAEELDRE 462
Query: 6261 HPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVI 6082
+ E + ++ + A W L E ++++ L + L L + + +++
Sbjct: 463 NYHGKERVRRREQEVMAKWRQLLELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQF 522
Query: 6081 GADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEK 5902
++++ + G E LL++H + +++ ++ + ++ + ++L
Sbjct: 523 ASEDVGPHLLGVEELLQAHSLQELQVNTYGETLKRFNRQALPYKSSEHKDAALLAQRLAD 582
Query: 5901 LDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEH 5722
L+ S LL RR E+ + F D + E+W+ ++ L +V
Sbjct: 583 LEEAYSELLRRSAARRARLEEARNFHHFMEDYDNEESWLVDKQRICKTGITAKDLRAVLS 642
Query: 5721 LIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXX 5542
L +KH+ E + +++ K + +LI QH + ++
Sbjct: 643 LQQKHKALEDEIKSRKPKSGQMSTAGKRLIGEQHPRSSEIQSRIDSLAEHWQALEALVEL 702
Query: 5541 RGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSY-LDPTNIRGKLQKHINFEQELKA 5365
R L+++ + F D +E SW+ EK++ Y D + + LQ+H + + EL A
Sbjct: 703 RRRQLEDAAEAYQFYTDANEAESWLNEKIALVNSRDYGNDEPSAQALLQRHRDLQGELNA 762
Query: 5364 NENRLDDIRSTGEQIIDSG 5308
+ ++ +++I +G
Sbjct: 763 YSGDILNLNQQADKLIKAG 781
Score = 38.9 bits (89), Expect = 1.9
Identities = 57/242 (23%), Positives = 94/242 (38%), Gaps = 16/242 (6%)
Frame = -1
Query: 1092 SWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQ--------RSLSSAEEDFRQLQDLDRR 937
SW +L NSLE I+ A E++ + S E + + L
Sbjct: 290 SWIRQKTLELEQRDLPNSLEGIQRELLAFKEYRTIEKPPKYKERSEIEALYFTINTL--- 346
Query: 936 IKSFNVGP-NPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLAN 760
+K+ N P NP ++ +E W+ L+ RE L E RQE+ ++L +F K +
Sbjct: 347 LKALNQPPYNPQDGQLVNDIEKAWQILEYAEHHREVALRDELLRQEKLEQLNYKFEKKSV 406
Query: 759 AFHAWLTNTRQEMMEAGGTLEEQLDAVERKAKEIKAN-KGQLRQIEEKGAM---LERNLI 592
+L Q + + Q+DA +K + I A+ ++ + + AM L+R
Sbjct: 407 LREGYLKEMIQVLSDP--RYLRQVDATLKKHEAISADILARVERFNDLTAMAEELDRENY 464
Query: 591 LDNRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARN---QSGVSEEALREFSMMFKH 421
+ W QL +L + NL Q N + + EA+RE F
Sbjct: 465 HGKERVRRREQEVMAKWRQLLELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQFAS 524
Query: 420 FD 415
D
Sbjct: 525 ED 526
>gi|45552923|ref|NP_995988.1| CG12008-PB [Drosophila melanogaster]
gi|45445784|gb|AAS64958.1| CG12008-PB [Drosophila melanogaster]
Length = 4118
Score = 756 bits (1952), Expect = 0.0
Identities = 577/2347 (24%), Positives = 1044/2347 (43%), Gaps = 92/2347 (3%)
Frame = -1
Query: 7128 KRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENFRDPSNLQAKIQKHEA-------F 6970
K+ L + Q F R+AD+++ T E F + +NL A + + EA F
Sbjct: 1283 KQKWLLQCVDLQMFNREADKIDA------TTKSHEAFLEYNNLGASLDEVEAILKRHLDF 1336
Query: 6969 EAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQA 6790
E + A K + + +I ++H+ S++I R ++ + LQ +
Sbjct: 1337 EKSLMAQDKILKGFSDNADKLISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQAS 1396
Query: 6789 LKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEI 6610
F + D++ W+++K T + ++ DL ++ +K F +EL ++ ++ +
Sbjct: 1397 KDFHKFAAEADDLKVWLQDK-TRIAGDENYRDLSNLPRKLQKHQAFERELRANEGQLRNV 1455
Query: 6609 NQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETL 6430
+ LV+ G+ ++ + D+N W L TL+ + L A + NR ++
Sbjct: 1456 TKDGQALVQAGNRV-PEVESRVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAK 1514
Query: 6429 AWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDR 6250
+ E D AL S D G DL + + L K + E ++ + K+ +L +A
Sbjct: 1515 KKVDELDSALRSGDVGNDLRSCKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFN 1574
Query: 6249 AEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADE 6070
A+ I + + + L++ Q R+ LE S H+F+ + WI + ++E
Sbjct: 1575 AQNIEAGTKELQQRFKDLRDPTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKSNE 1634
Query: 6069 LAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHE 5890
L +++ A++L + H++ + EI N+ AGQ L+ PE +V+ ++L+
Sbjct: 1635 LGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALVAGQSLISQQHPEREQVESLCQQLEQA 1694
Query: 5889 KSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKK 5710
L ER + + Q + D + E+W+ ++ L +T+ G DS L+ K
Sbjct: 1695 WQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLLTK 1754
Query: 5709 HEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNA 5530
H+ E L + + ++ H + +A R
Sbjct: 1755 HKTIELELDTYSGIVTEMGHSCAAMVAANHPDSKVLAAKQQLIEKMLKSLHKLASQRQGR 1814
Query: 5529 LKESYKRQTFDRDCDEMVSWITEKLSTARDDSY-LDPTNIRGKLQKHINFEQELKANENR 5353
L ES + + + DE+ WI E+ A + Y D +++ K + + ++ +R
Sbjct: 1815 LMESLYKHEYFLESDEVEQWIREQEQAASSEDYGQDFEHLQLLQNKFDDLKHRVEVGADR 1874
Query: 5352 LDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNI 5173
+D +++IDS A+ + R Q+ W L+ N++ KL AG +F+R++
Sbjct: 1875 VDQCELLAKKLIDSESPYANEVEKRQEQLRTSWENLLQLLNQREQKLHAAGEIHRFHRDV 1934
Query: 5172 EDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEE 4993
+ + + + S++ G+DL S L +K E+D A ++ + + + + Q +
Sbjct: 1935 AEALFRIQD-KNAALSQELGRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSVRLQAK 1993
Query: 4992 EHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVA 4813
NA I ++Q+ + +N L++ R +L S D+ D ++W
Sbjct: 1994 YPSNASAIAQQQDKVVAAWNDLKERSTARGDRLAASSDLQTFLTDVRDIVSWSSNLRAAL 2053
Query: 4812 GSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQ 4633
+ D G L + A+ EI + + ++ ++ M+Q GH+ A ++ +K A
Sbjct: 2054 QAEEHVSDAAGATALKIQHDAIYGEIEAREDKFRYLNELSDSMVQTGHYAAADVEEKCAA 2113
Query: 4632 LRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEA 4453
+ D + L + K++ L+ + +L DA + D S ++ + S+D+G+ + +
Sbjct: 2114 MLDERQKLHAAWNKKKIMLEQKIDLFCFLRDAKQIDNLSSSQQAALSSSDFGQTVEDVQN 2173
Query: 4452 LLKKH----RALLSDLEAFKGTIEDLRKQASQCKYQEQPM-------------------- 4345
++KH R + + E E RK Q Y +
Sbjct: 2174 KIRKHDEFERLIQTQEEKVSLLQEHGRKLIEQRHYDSANIQTILQGVLARRQKVKDLCAV 2233
Query: 4344 -----------GQLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQ 4198
+ RDC A Y EK + + D + +N D ++ Q
Sbjct: 2234 RRYKLEDALLYAKFVRDCAEAKYWINEKQKK----LEADAASYAEVTNLDEKIKKLQKHQ 2289
Query: 4197 GFVPAAYVKRIEPGTAQQHAQQQVNSIG----GKQSE-----------IEDKYQRLMMLG 4063
F A Q Q++ G KQ E + + +Q L+
Sbjct: 2290 AFQAEV--------AANQGRIQEIQDTGVILLSKQHESSPEIKRAIEIVLEAWQGLLAEL 2341
Query: 4062 ETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDL 3883
E R R LEEA + + + + WI+ +E + + G DLE L +K DD D+
Sbjct: 2342 EQRGRGLEEAQDSLEFNSQLDKIEAWIRDKEMMVQASDTGRDLEHCNALMRKLDDVDSDM 2401
Query: 3882 KANEVRLQEMNQIATALTSVGQTETAVR-IRQQIEDLNARWRALXXXXXXXXXQLGSAHE 3706
+ ++ R++ +NQ+A L + Q + + ++ +D N WR L LG A+E
Sbjct: 2402 RVDDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYNWRQLQGALNAYRALLGGANE 2461
Query: 3705 VQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDE 3526
+ F+RDVD+T D I EK A+ S D GRDL +V+AL R+ E +ERD++A+ KI +
Sbjct: 2462 IHVFNRDVDDTADRIAEKSLAMSSTDTGRDLAAVEALIRREEALERDMSAVKQKIDQHET 2521
Query: 3525 KANRLRQSHPE-AAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQ 3349
A L + +PE A+ I EL++ W L + + R+ L ++Y +F+SD ++L
Sbjct: 2522 AAEFLIKKYPERGAQHIERKLEELHKSWGNLQALSVKRQSILNEAYLAHKFVSDVKELEL 2581
Query: 3348 WIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAA 3169
W+ M + +++ + + + E LE HQE + EI+ R F Q G QL
Sbjct: 2582 WVNDMIKKMNNTQSPSTINDCETQLELHQERKVEIEGRQEAFAGLKQQGEQLSKRPQQQQ 2641
Query: 3168 GD-IENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQED 2992
D + L + E + L +AW R L + +LQLF EQ + W++ +EAFL +D
Sbjct: 2642 PDNVRKYLLVLEELHQTLNEAWSERARDLTEAHQLQLFKAQVEQVEIWLANKEAFLNNDD 2701
Query: 2991 PSGDN---VESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILD 2821
GD+ VE L+KKH++F+K ++ + + L+ FA S+++ D+ + K IL
Sbjct: 2702 -LGDSYTAVERLLKKHDEFEKLLHA--DHVDTLQKFANSILEGEPKDADLIREKLAYILR 2758
Query: 2820 RWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNIQQKHQK 2641
R L E +++ +L +S LQ+F R EI+ W+ +K Q+A +ENYR+P+N+Q K QK
Sbjct: 2759 RKQKLLELSEERKQRLTQSHQLQEFLRSLYEIDRWLVQKLQVALDENYREPSNLQSKIQK 2818
Query: 2640 QQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKS 2461
AF+AEL +NS R+ ++I G LI E A +L L W L + K
Sbjct: 2819 HAAFDAELLSNSPRVQSVIHEGERLIRGDHFAKDEIAQQVQL--LEGDWLKLKGASQTKK 2876
Query: 2460 YRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQ 2281
+L++A +F +V + W+ EVE+ L SEDYGKDLA+V NLLKKH LEAD+ H
Sbjct: 2877 DKLQQAYDALAFNRSVDEFNNWMDEVELQLSSEDYGKDLAAVSNLLKKHERLEADVAHHG 2936
Query: 2280 DRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFR 2101
+ ++ ++ + + + F +I ER + RY+ + + RR+ L +L++ QF R
Sbjct: 2937 ELADQLKQKDEQFFQAEHFLRHEIHERATVSIRRYNTLHEPLGIRRENLEDSLSLQQFLR 2996
Query: 2100 DIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELL 1921
D +DE W+ EK+L+ S D G L VQ L++KH ++ EL S EP + + +G++++
Sbjct: 2997 DAEDELQWLAEKQLVAGSQDLGTSLLSVQGLQKKHNSLEAELTSQEPLIQALLQRGQQMI 3056
Query: 1920 RSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNE 1741
R + +Q++ + E L++ Q+RDL R RL ++ Q F + E +AWM E
Sbjct: 3057 R---DNHFASEQLQYKSELLQKQLVQLRDLAAIRRLRLLDAVESQLFYVEANEADAWMRE 3113
Query: 1740 KQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIK 1561
K+ +L S ++G + VQG KK + Q +L K + + LI + + +I
Sbjct: 3114 KRPVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPSIEKVAKLATGLIERNHFDSSNIA 3173
Query: 1560 QRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDL 1381
++ Q+ ++ +A+ R ++L + +++ + + + W+ ++ SED+G D+
Sbjct: 3174 EKNAQVGQEYEDLLRLAKERESRLGECKKLFEYLRETEELHEWVGDQMAVTASEDYGEDV 3233
Query: 1380 SSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNL 1201
V+ L+ E+F + LNA E ++ E D+L+ + +I+ + Q W+ L
Sbjct: 3234 EHVEQLILAFESFVSNLNANEAR-VEACLERGDRLIQENNPYRSSIKSKRDETKQLWEEL 3292
Query: 1200 L----AHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLE 1033
A +A E + L K AS + E+ +D LE
Sbjct: 3293 KDLVHARQDALAGAKQVHVYDRVADETIQLINEKDASLIS---EDYGQD---------LE 3340
Query: 1032 EIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQR 853
I+AL H F+ L + + ++ + D + W +L+
Sbjct: 3341 SIQALGRKHQVFESELVGIQGQVDSVLAEAAKLGEIYPDAKEHIEVKRDETVEAWTDLKE 3400
Query: 852 IIKEREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEMMEAGGTLEEQLDAVER 673
R+ +L++ Q Q D+ R A + N A +T AG L L + +
Sbjct: 3401 KTAARKNKLSQAEQLQSYFDEYRDLIAWI-NEMLAKITAPELANSVAGAEL--LLASTKD 3457
Query: 672 KAKEIKANKGQLRQIEEKGAMLERNLILDNRYTEHST---VGIAQAWDQL---------- 532
EI+ + G + LI + + H + + QA +L
Sbjct: 3458 HDTEIRTRDETFAKFAANG----QQLIKEKHFLAHEVEDKIKVLQARHELLKHTLNKRRE 3513
Query: 531 -------DQLAMRMQHNLEQQIQAR----NQSGVSEEALREFSMMFKHFDKEKTGRLDHQ 385
QL ++ LEQ I +R + + + + ++ +H D EKT +
Sbjct: 3514 IYELNLDTQLFLKDAEILEQWISSREPQLKDTKLGDSIPQVEDLLRRHEDFEKTVAAQEE 3573
Query: 384 QFKSCLR 364
+F++ R
Sbjct: 3574 KFQAIKR 3580
Score = 755 bits (1949), Expect = 0.0
Identities = 547/2178 (25%), Positives = 1007/2178 (46%), Gaps = 67/2178 (3%)
Frame = -1
Query: 6924 KTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILY 6745
+T I N ++ ++KR + ++ + + L+ ++ L F R+CD+
Sbjct: 936 RTSTQSINEN---ADSVEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEK 992
Query: 6744 WIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEH 6565
W++EKE + +++ E V+ +RKF+ F+ +L R+ EI+ A D +GHS+
Sbjct: 993 WMKEKERMIKSDEG----EGVDNAKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQL 1048
Query: 6564 DQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDY 6385
D+I ++ ++ W RLN A R++ L GA V+ FNR DE W+ EK L L +
Sbjct: 1049 DKIIARQRQIHQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVI 1108
Query: 6384 GRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAW 6205
DL VQALQR+H+ ER+LA +E K+ ++ + + +P + ++ + + + W
Sbjct: 1109 TPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQDMW 1168
Query: 6204 NALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESH 6025
++++ ++ +E F + L++WI +K + ADE A+DV A LL+ H
Sbjct: 1169 QQVQQRGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKH 1228
Query: 6024 QEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILY 5845
+ +I A F + G++L + G P E +E+L E+ ++ W E++
Sbjct: 1229 NDLGDDIRAHDTEFVEVIQLGKQLSD-GKPNMAETVAVIERLKAEQDAIHRGWAEKQKWL 1287
Query: 5844 EQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKI 5665
QC+DLQ+F R+ ++ + EAFL +LG SLD VE ++K+H DFEKSL AQ++ +
Sbjct: 1288 LQCVDLQMFNREADKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLDFEKSLMAQDKIL 1347
Query: 5664 NALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCD 5485
+ A KLI HY + + + R L+ S F + D
Sbjct: 1348 KGFSDNADKLISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEAD 1407
Query: 5484 EMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGH 5305
++ W+ +K A D++Y D +N+ KLQKH FE+EL+ANE +L ++ G+ ++ +G+
Sbjct: 1408 DLKVWLQDKTRIAGDENYRDLSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQAGN 1467
Query: 5304 FAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVAS 5125
+ + R+ +N W +L+ + KG KL +A ++++ NR++ED + + EL+ + S
Sbjct: 1468 RVPE-VESRVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDSALRS 1526
Query: 5124 EDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQ 4945
D G DL S ++L K ++ES+ + +V + HFNA I + LQ
Sbjct: 1527 GDVGNDLRSCKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQ 1586
Query: 4944 QRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLI 4765
QR+ LRDP ++R+ KL ES ++ +++ E WI E A S G++L Q+L
Sbjct: 1587 QRFKDLRDPTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKSNELGQNLHQAQSLH 1646
Query: 4764 KKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRR 4585
KK + L AEI H I A +I Q H ++ QL W+ L+ +R
Sbjct: 1647 KKHKKLEAEIKGHQPMINKALVAGQSLISQQHPEREQVESLCQQLEQAWQDLERHCGERS 1706
Query: 4584 TDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFK 4405
LD SL+A QYL DA E ++W+ E+ ++ ST+YG+D DSA LL KH+ + +L+ +
Sbjct: 1707 RKLDMSLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLLTKHKTIELELDTYS 1766
Query: 4404 GTIEDLRKQASQCKYQEQPMGQLGRDCVLALYDYQEKSPREVSMKKGDVLT-------LL 4246
G + ++ + P ++ + + + S ++G ++ L
Sbjct: 1767 GIVTEMGHSCAAMVAANHPDSKVLAAKQQLIEKMLKSLHKLASQRQGRLMESLYKHEYFL 1826
Query: 4245 NASNRDWWKVEVNDR-------QGFVPAAYVK--------RIEPGT-----AQQHAQQQV 4126
+ + W E Q F ++ R+E G + A++ +
Sbjct: 1827 ESDEVEQWIREQEQAASSEDYGQDFEHLQLLQNKFDDLKHRVEVGADRVDQCELLAKKLI 1886
Query: 4125 NS-------IGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREA 3967
+S + +Q ++ ++ L+ L R++KL A + ++ R+ + I+ + A
Sbjct: 1887 DSESPYANEVEKRQEQLRTSWENLLQLLNQREQKLHAAGEIHRFHRDVAEALFRIQDKNA 1946
Query: 3966 VAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQ 3787
A QE+G DL L +K + F+ DL A E +LQ + + + L A I QQ
Sbjct: 1947 -ALSQELGRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSVRL-QAKYPSNASAIAQQ 2004
Query: 3786 IEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRS 3607
+ + A W L +L ++ ++Q F DV + W AL +E+ D
Sbjct: 2005 QDKVVAAWNDLKERSTARGDRLAASSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAG 2064
Query: 3606 VQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSK 3427
AL+ +H+ + ++ A DK + L+E ++ + Q+ AA + + + ++ +L +
Sbjct: 2065 ATALKIQHDAIYGEIEAREDKFRYLNELSDSMVQTGHYAAADVEEKCAAMLDERQKLHAA 2124
Query: 3426 ANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTE 3247
N +K L D FL D + + +S +SS + V + + +H E+
Sbjct: 2125 WNKKKIMLEQKIDLFCFLRDAKQIDNLSSSQQAALSSSDFGQTVEDVQNKIRKHDEFERL 2184
Query: 3246 IDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLEL 3067
I ++ + G +L+ HY + +I+ LQGV R+ ++D RR L+ L
Sbjct: 2185 IQTQEEKVSLLQEHGRKLIEQRHYDSANIQTILQGVLARRQKVKDLCAVRRYKLEDALLY 2244
Query: 3066 QLFYRDCEQADTWMSAREAFLAQEDPSGDNVESL------IKKHEDFDKAINTQEEKIKG 2905
F RDC +A W++ ++ L + S V +L ++KH+ F + + +I+
Sbjct: 2245 AKFVRDCAEAKYWINEKQKKLEADAASYAEVTNLDEKIKKLQKHQAFQAEVAANQGRIQE 2304
Query: 2904 LKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEI 2725
++ L+ H SP + R + +L+ W GL L Q+ L E+Q +F+ D+I
Sbjct: 2305 IQDTGVILLSKQHESSPEIKRAIEIVLEAWQGLLAELEQRGRGLEEAQDSLEFNSQLDKI 2364
Query: 2724 ENWMTEKFQIAQ-EENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKC 2548
E W+ +K + Q + RD + +K ++++ + R+ I Q + LI A+
Sbjct: 2365 EAWIRDKEMMVQASDTGRDLEHCNALMRKLDDVDSDMRVDDQRVKHINQLADKLINQAQV 2424
Query: 2547 GGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQ 2368
+V R K N W L L AN+ F V D + E + +
Sbjct: 2425 PADTQSVDKRRKDFNYNWRQLQGALNAYRALLGGANEIHVFNRDVDDTADRIAEKSLAMS 2484
Query: 2367 SEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERR-KL 2191
S D G+DLA+VE L+++ LE D+ A + ++ + A+ L++ +G Q ER+ +
Sbjct: 2485 STDTGRDLAAVEALIRREEALERDMSAVKQKIDQHETAAEFLIKKYPERGAQHIERKLEE 2544
Query: 2190 IADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQN 2011
+ + ++ ++ R+ L++A H+F D+ + E W+ + +++ + +
Sbjct: 2545 LHKSWGNLQALSVKRQSILNEAYLAHKFVSDVKELELWVNDMIKKMNNTQSPSTINDCET 2604
Query: 2010 LRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDL 1831
H+ E+ + + +K +GE+L + + D ++K + LE+ + +
Sbjct: 2605 QLELHQERKVEIEGRQEAFAGLKQQGEQLSKRPQQQ--QPDNVRKYLLVLEELHQTLNEA 2662
Query: 1830 TGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVD 1651
R + L E+ Q F VE+ E W+ K+ L +D+ G++ V+ LLKKHD F +
Sbjct: 2663 WSERARDLTEAHQLQLFKAQVEQVEIWLANKEAFLNNDDLGDSYTAVERLLKKHDEF--E 2720
Query: 1650 LELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAY 1471
LH V L ++++ A I+++ + R ++ ++E R +L +
Sbjct: 2721 KLLHADHVDTLQKFANSILEGEPKDADLIREKLAYILRRKQKLLELSEERKQRLTQSHQL 2780
Query: 1470 LQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITE 1291
+F+ ++ W+ +K Q E++ R+ S++Q + K AFDA L + +Q +
Sbjct: 2781 QEFLRSLYEIDRWLVQKLQVALDENY-REPSNLQSKIQKHAAFDAELLS-NSPRVQSVIH 2838
Query: 1290 LKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELY--LAF 1117
++L+ +H I ++ + W L S+ ++ ++++ Y LAF
Sbjct: 2839 EGERLIRGDHFAKDEIAQQVQLLEGDWLKLKGASQTKK----------DKLQQAYDALAF 2888
Query: 1116 AKKASTFNSWFENAEEDLT------DPVRCNSL----EEIRALRDAHGEFQRSLSSAEED 967
+ FN+W + E L+ D ++L E + A HGE L +E
Sbjct: 2889 NRSVDEFNNWMDEVELQLSSEDYGKDLAAVSNLLKKHERLEADVAHHGELADQLKQKDEQ 2948
Query: 966 FRQLQDLDRR---------IKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQEL--AR 820
F Q + R I+ +N P + LED+ +LQ+ +++ E EL
Sbjct: 2949 FFQAEHFLRHEIHERATVSIRRYNTLHEP-LGIRRENLEDS-LSLQQFLRDAEDELQWLA 3006
Query: 819 EHQRQEENDKLRREFAKLANAFHAWLTNTRQEMMEAGGTLEEQL--DAVERKAKEIKANK 646
E Q + L + + +EA T +E L ++R + I+ N
Sbjct: 3007 EKQLVAGSQDLGTSLLSVQG------LQKKHNSLEAELTSQEPLIQALLQRGQQMIRDNH 3060
Query: 645 GQLRQIEEKGAMLERNLI 592
Q++ K +L++ L+
Sbjct: 3061 FASEQLQYKSELLQKQLV 3078
Score = 637 bits (1643), Expect = e-180
Identities = 404/1525 (26%), Positives = 749/1525 (48%), Gaps = 100/1525 (6%)
Frame = -1
Query: 5472 WITEKLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAAD 5293
++ E + D YL + L+KH ++ A R +D+ + E++ + +
Sbjct: 411 YLKEMIQVLSDPRYL--RQVDATLKKHEAISADILARVERFNDLTAMAEELDRENYHGKE 468
Query: 5292 HIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYG 5113
+ R ++V W +L++ + L + N R I + EL+ Q ASED G
Sbjct: 469 RVRRREQEVMAKWRQLLELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQFASEDVG 528
Query: 5112 KDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYN 4933
L+ V+ L + L E N + + + + A ++ EH +A ++ ++ +L++ Y+
Sbjct: 529 PHLLGVEELLQAHSLQELQVNTYGETLKRFNRQALPYKSSEHKDAALLAQRLADLEEAYS 588
Query: 4932 ALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQ 4753
L R+ +L E+ + D ++E +W+ +K+++ + +DL V +L +K +
Sbjct: 589 ELLRRSAARRARLEEARNFHHFMEDYDNEESWLVDKQRICKTGITAKDLRAVLSLQQKHK 648
Query: 4752 ALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLD 4573
AL EI + + +S+A +I + H + EI+ ++ L ++W+ L++ E RR L+
Sbjct: 649 ALEDEIKSRKPKSGQMSTAGKRLIGEQHPRSSEIQSRIDSLAEHWQALEALVELRRRQLE 708
Query: 4572 DSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIE 4393
D+ +A+Q+ +DANEA++W++EK +V S DYG DE SA+ALL++HR L +L A+ G I
Sbjct: 709 DAAEAYQFYTDANEAESWLNEKIALVNSRDYGNDEPSAQALLQRHRDLQGELNAYSGDIL 768
Query: 4392 DLRKQ------ASQCKYQ----EQPMGQLGRD---------------------------- 4327
+L +Q A C + E + ++ ++
Sbjct: 769 NLNQQADKLIKAGICTLELSAAEPELPEVEQEEWVNETRLVPKEVWEDEWVEKLEHKKVT 828
Query: 4326 ------CVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEV-NDRQGFVPAAYVKR 4168
V +L+ ++ + + M KG+V+ L + +N DWW V N +GFVPA YV+
Sbjct: 829 ETKMLPHVKSLFPFEGQG---MKMDKGEVMLLKSKTNDDWWCVRKDNGVEGFVPANYVRE 885
Query: 4167 IEPG-----------------------------------------------TAQQHAQQQ 4129
+EP T+ Q +
Sbjct: 886 VEPRPVACIVPKAEKVKSLQKVKKTILVRQVVPVKRIKPVSVAPKPLVQRRTSTQSINEN 945
Query: 4128 VNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQE 3949
+S+ +Q I Y L + + R LE++ + RE +D +W+K +E + E
Sbjct: 946 ADSVEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKERMIKSDE 1005
Query: 3948 IGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNA 3769
E V+ ++KF+ F DL A R++E++ G ++ I +Q ++
Sbjct: 1006 G----EGVDNAKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDKIIARQ-RQIHQ 1060
Query: 3768 RWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQR 3589
W+ L L A V+ F+R DE + W+ EK LD+ DLR+VQALQR
Sbjct: 1061 IWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVITPDLRTVQALQR 1120
Query: 3588 KHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKE 3409
+H+ +ER+LA + DK+ + N ++ ++P + + Q+E+ + W ++ + ++ +
Sbjct: 1121 RHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQDMWQQVQQRGSDLRN 1180
Query: 3408 KLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAA 3229
++ Q F + + L+ WI S+ +++ E A DV A LL++H + +I +
Sbjct: 1181 RIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDLGDDIRAHDT 1240
Query: 3228 TFQAFDQFGNQLLNSHHYAAGDIE--NRLQGVNEARKGLEDAWVARRNILDQCLELQLFY 3055
F Q G QL + A + RL+ +A + W ++ L QC++LQ+F
Sbjct: 1241 EFVEVIQLGKQLSDGKPNMAETVAVIERLKAEQDA---IHRGWAEKQKWLLQCVDLQMFN 1297
Query: 3054 RDCEQADTWMSAREAFLAQED--PSGDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESL 2881
R+ ++ D + EAFL + S D VE+++K+H DF+K++ Q++ +KG A+ L
Sbjct: 1298 READKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLDFEKSLMAQDKILKGFSDNADKL 1357
Query: 2880 IKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKF 2701
I N+HYDS + +R+Q+L + +K+ +++ L S+ +F+ +AD+++ W+ +K
Sbjct: 1358 ISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKT 1417
Query: 2700 QIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSA 2521
+IA +ENYRD +N+ +K QK QAFE EL AN ++ + + G L++ G V +
Sbjct: 1418 RIAGDENYRDLSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQ---AGNRVPEVES 1474
Query: 2520 RLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLA 2341
R+ LN +W L+ + +K +L++A Q+ +++D + + E++ L+S D G DL
Sbjct: 1475 RVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDSALRSGDVGNDLR 1534
Query: 2340 SVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKK 2161
S ++L+ K +LE++I +V E+ D + F Q I K + R+ ++
Sbjct: 1535 SCKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQQRFKDLRD 1594
Query: 2160 MATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDT 1981
RR KL ++LN H+F ++D E WI E S++ G++L Q+L +KH++++
Sbjct: 1595 PTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKSNELGQNLHQAQSLHKKHKKLEA 1654
Query: 1980 ELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDE 1801
E+ H+P ++ + G+ L+ ++ +Q++ + LEQ+W + G R ++LD
Sbjct: 1655 EIKGHQPMINKALVAGQSLI---SQQHPEREQVESLCQQLEQAWQDLERHCGERSRKLDM 1711
Query: 1800 SEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVAD 1621
S Q +L D E E+W+ E+ +L S +G + LL KH T +++L+ + V +
Sbjct: 1712 SLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLLTKHKTIELELDTYSGIVTE 1771
Query: 1620 LINKGDTLIHNGNHHAPHIKQRCDQLRARLIE-IESMAEGRLAKLRDNSAYLQFMWKCDV 1444
+ + ++ NH + QL ++++ + +A R +L ++ ++ + D
Sbjct: 1772 MGHSCAAMV-AANHPDSKVLAAKQQLIEKMLKSLHKLASQRQGRLMESLYKHEYFLESDE 1830
Query: 1443 VESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITE---LKDQLV 1273
VE WI E+EQ SED+G+D +Q+L Q FD L G R+ + L +L+
Sbjct: 1831 VEQWIREQEQAASSEDYGQDFEHLQLL---QNKFD-DLKHRVEVGADRVDQCELLAKKLI 1886
Query: 1272 SSEHQQSPAIEKRHTNVIQRWQNLL 1198
SE + +EKR + W+NLL
Sbjct: 1887 DSESPYANEVEKRQEQLRTSWENLL 1911
Score = 610 bits (1573), Expect = e-172
Identities = 410/1364 (30%), Positives = 666/1364 (48%), Gaps = 44/1364 (3%)
Frame = -1
Query: 7176 QEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEE--NFRDPSN 7003
Q VL KD +R +LE+A + F RD E WI EK + + + ++ + +N
Sbjct: 2218 QGVLARRQKVKDLCAVRRYKLEDALLYAKFVRDCAEAKYWINEKQKKLEADAASYAEVTN 2277
Query: 7002 LQAKI---QKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXX 6832
L KI QKH+AF+AEV A+ I + TG ++ H +S IK+ +E + W
Sbjct: 2278 LDEKIKKLQKHQAFQAEVAANQGRIQEIQDTGVILLSKQHESSPEIKRAIEIVLEAWQGL 2337
Query: 6831 XXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDF 6652
+G L++A L F Q D+I WIR+KE V A D G DLEH L RK DD
Sbjct: 2338 LAELEQRGRGLEEAQDSLEFNSQLDKIEAWIRDKEMMVQASDTGRDLEHCNALMRKLDDV 2397
Query: 6651 LKELGNHQYRINEINQAADKLVEEGHSEHD--QIYKKRDDVNDAWHRLNTLAATRKEGLF 6478
++ R+ INQ ADKL+ + D + K+R D N W +L + L
Sbjct: 2398 DSDMRVDDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYNWRQLQGALNAYRALLG 2457
Query: 6477 GAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKML 6298
GA+++ FNRD D+T I EK LA+SS D GRDL V+AL R+ E ERD++A++ K+
Sbjct: 2458 GANEIHVFNRDVDDTADRIAEKSLAMSSTDTGRDLAAVEALIRREEALERDMSAVKQKID 2517
Query: 6297 QLEKEAHKLAETHPDR-AEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYR 6121
Q E A L + +P+R A+ I +K ++ +W L+ + R+ L ++ H+F++D +
Sbjct: 2518 QHETAAEFLIKKYPERGAQHIERKLEELHKSWGNLQALSVKRQSILNEAYLAHKFVSDVK 2577
Query: 6120 DLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMG 5941
+L W+ DM + + + E LE HQE K EI+ R ++F G++L +
Sbjct: 2578 ELELWVNDMIKKMNNTQSPSTINDCETQLELHQERKVEIEGRQEAFAGLKQQGEQLSKRP 2637
Query: 5940 IPESPE-VQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFL 5764
+ P+ V++ L L+ +L W ER + LQLF EQ E W+ +EAFL
Sbjct: 2638 QQQQPDNVRKYLLVLEELHQTLNEAWSERARDLTEAHQLQLFKAQVEQVEIWLANKEAFL 2697
Query: 5763 ANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXX 5584
N DLGDS +VE L+KKH++FEK L A + ++ L +FA +++G+ AD + E
Sbjct: 2698 NNDDLGDSYTAVERLLKKHDEFEKLLHA--DHVDTLQKFANSILEGEPKDADLIREKLAY 2755
Query: 5583 XXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGK 5404
R L +S++ Q F R E+ W+ +KL A D++Y +P+N++ K
Sbjct: 2756 ILRRKQKLLELSEERKQRLTQSHQLQEFLRSLYEIDRWLVQKLQVALDENYREPSNLQSK 2815
Query: 5403 LQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKK 5224
+QKH F+ EL +N R+ + GE++I HFA D I +++ + W +L A+ K
Sbjct: 2816 IQKHAAFDAELLSNSPRVQSVIHEGERLIRGDHFAKDEIAQQVQLLEGDWLKLKGASQTK 2875
Query: 5223 GAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAH 5044
KL++A + FNR++++ W+ E+E Q++SEDYGKDL +V NL KK +E+D H
Sbjct: 2876 KDKLQQAYDALAFNRSVDEFNNWMDEVELQLSSEDYGKDLAAVSNLLKKHERLEADVAHH 2935
Query: 5043 NDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLF 4864
+ D +KQ +QF + EHF I + +RYN L +PL R+ L +S Q
Sbjct: 2936 GELADQLKQKDEQFFQAEHFLRHEIHERATVSIRRYNTLHEPLGIRRENLEDSLSLQQFL 2995
Query: 4863 RDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDM 4684
RD EDEL W+ EK+ VAGS + G L+ VQ L KK +L AE+ + + I+++ M
Sbjct: 2996 RDAEDELQWLAEKQLVAGSQDLGTSLLSVQGLQKKHNSLEAELTSQEPLIQALLQRGQQM 3055
Query: 4683 IQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKE 4504
I+ HF + +++ K L+ L+ A RR L D++++ + +ANEADAWM EK
Sbjct: 3056 IRDNHFASEQLQYKSELLQKQLVQLRDLAAIRRLRLLDAVESQLFYVEANEADAWMREKR 3115
Query: 4503 PIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQAS--------QCKYQEQP 4348
P++ S+DYG+DE S + KK L +L AFK +IE + K A+ +
Sbjct: 3116 PVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPSIEKVAKLATGLIERNHFDSSNIAEK 3175
Query: 4347 MGQLGRDCVLALYDYQEKSPREVSMKK---------------GDVLTLLNASNRDWWKVE 4213
Q+G++ L +E+ R KK GD + + AS VE
Sbjct: 3176 NAQVGQEYEDLLRLAKERESRLGECKKLFEYLRETEELHEWVGDQMA-VTASEDYGEDVE 3234
Query: 4212 VNDRQGFVPAAYVKRIEPGTAQ------------QHAQQQVNSIGGKQSEIEDKYQRLMM 4069
++ ++V + A+ Q +SI K+ E + ++ L
Sbjct: 3235 HVEQLILAFESFVSNLNANEARVEACLERGDRLIQENNPYRSSIKSKRDETKQLWEELKD 3294
Query: 4068 LGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKG 3889
L R+ L A + + R A++ + I ++A ++ G DLE ++ L +K F+
Sbjct: 3295 LVHARQDALAGAKQVHVYDRVADETIQLINEKDASLISEDYGQDLESIQALGRKHQVFES 3354
Query: 3888 DLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAH 3709
+L + ++ + A L + + I + ++ W L +L A
Sbjct: 3355 ELVGIQGQVDSVLAEAAKLGEI-YPDAKEHIEVKRDETVEAWTDLKEKTAARKNKLSQAE 3413
Query: 3708 EVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLD 3529
++Q + + + WI E + + + + + L + + ++ +
Sbjct: 3414 QLQSYFDEYRDLIAWINEMLAKITAPELANSVAGAELLLASTKDHDTEIRTRDETFAKFA 3473
Query: 3528 EKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQ 3349
+L + A ++ D + L + L N R+E + D Q FL D L Q
Sbjct: 3474 ANGQQLIKEKHFLAHEVEDKIKVLQARHELLKHTLNKRREIYELNLDTQLFLKDAEILEQ 3533
Query: 3348 WIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQA 3217
WI+S + +L + + E LL RH+++ + ++ FQA
Sbjct: 3534 WISSREPQLKDTKLGDSIPQVEDLLRRHEDFEKTVAAQEEKFQA 3577
Score = 544 bits (1401), Expect = e-152
Identities = 479/2308 (20%), Positives = 974/2308 (41%), Gaps = 62/2308 (2%)
Frame = -1
Query: 7191 IHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENFRD 7012
I RR +VLG KD + ++ L+ ++ F F +AD+L VW+ +K + A +EN+RD
Sbjct: 1368 IGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKTRIAGDENYRD 1427
Query: 7011 PSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXX 6832
SNL K+QKH+AFE E++A+ + N+ K G A++Q + E ++ R+ +L+ W
Sbjct: 1428 LSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQAGNRVPE-VESRVADLNKRWKDL 1486
Query: 6831 XXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDF 6652
KG KL+QA R ++ + E ++ + + D+G DL + L K
Sbjct: 1487 LTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDSALRSGDVGNDLRSCKDLINKQQIL 1546
Query: 6651 LKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGA 6472
E+ ++ E+ D + GH I ++ + L R+ L +
Sbjct: 1547 ESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQQRFKDLRDPTQRRRAKLEES 1606
Query: 6471 HQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQL 6292
+F + D WI E A S++ G++L+ Q+L +KH+ E A ++G +
Sbjct: 1607 LNYHKFVFELDSEFQWINEHLPAAKSNELGQNLHQAQSLHKKHKKLE---AEIKGHQPMI 1663
Query: 6291 EKEA----HKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADY 6124
K +++ HP+R E + + AW L+ R L+ S + ++L D
Sbjct: 1664 NKALVAGQSLISQQHPER-EQVESLCQQLEQAWQDLERHCGERSRKLDMSLKAQQYLFDA 1722
Query: 6123 RDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEM 5944
++ SW+G+ V+ + E +D A LL H+ + E+D + + + +V
Sbjct: 1723 GEIESWLGERNNVLRSTEYGRDRDSAAKLLTKHKTIELELDTYSGIVTEMGHSCAAMVAA 1782
Query: 5943 GIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFL 5764
P+S + K + ++ SL L +R+ + + ++ ++++ E W+ +QE
Sbjct: 1783 NHPDSKVLAAKQQLIEKMLKSLHKLASQRQGRLMESLYKHEYFLESDEVEQWIREQEQAA 1842
Query: 5763 ANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXX 5584
++ D G + ++ L K +D + + ++++ + A KLI + A++V +
Sbjct: 1843 SSEDYGQDFEHLQLLQNKFDDLKHRVEVGADRVDQCELLAKKLIDSESPYANEVEKRQEQ 1902
Query: 5583 XXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGK 5404
R L + + F RD E + I +K + + D +
Sbjct: 1903 LRTSWENLLQLLNQREQKLHAAGEIHRFHRDVAEALFRIQDKNAALSQELGRDLNSALAL 1962
Query: 5403 LQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKK 5224
L+KH FE +L A E +L + ++ A I + +V WN+L + + +
Sbjct: 1963 LRKHEGFENDLVALEAQLQVLVEDSVRLQAKYPSNASAIAQQQDKVVAAWNDLKERSTAR 2022
Query: 5223 GAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAH 5044
G +L + + Q F ++ D+ +W S L + +E++ D L+ + I + A
Sbjct: 2023 GDRLAASSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEAR 2082
Query: 5043 NDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLF 4864
D+ + +L+ + H+ A + K + L K+K L +
Sbjct: 2083 EDKFRYLNELSDSMVQTGHYAAADVEEKCAAMLDERQKLHAAWNKKKIMLEQKIDLFCFL 2142
Query: 4863 RDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDM 4684
RD + ++ S++ G+ + VQN I+K I + ++ + +
Sbjct: 2143 RDAKQIDNLSSSQQAALSSSDFGQTVEDVQNKIRKHDEFERLIQTQEEKVSLLQEHGRKL 2202
Query: 4683 IQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKE 4504
I+Q H+ + I+ L + + +K RR L+D+L +++ D EA W++EK+
Sbjct: 2203 IEQRHYDSANIQTILQGVLARRQKVKDLCAVRRYKLEDALLYAKFVRDCAEAKYWINEKQ 2262
Query: 4503 PIV--GSTDYGKDEDSAEAL--LKKHRALLSDLEAFKGTIEDLRKQ-ASQCKYQEQPMGQ 4339
+ + Y + + E + L+KH+A +++ A +G I++++ Q + +
Sbjct: 2263 KKLEADAASYAEVTNLDEKIKKLQKHQAFQAEVAANQGRIQEIQDTGVILLSKQHESSPE 2322
Query: 4338 LGRDCVLALYDYQ----EKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPA---- 4183
+ R + L +Q E R +++ N S D + + D++ V A
Sbjct: 2323 IKRAIEIVLEAWQGLLAELEQRGRGLEEAQDSLEFN-SQLDKIEAWIRDKEMMVQASDTG 2381
Query: 4182 -------AYVKRIEPGTAQQHAQQQ----VNSIGGKQSEIEDKYQRLMMLGETRK----- 4051
A +++++ + Q +N + K + + RK
Sbjct: 2382 RDLEHCNALMRKLDDVDSDMRVDDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYN 2441
Query: 4050 -RKLEEACKGYQLL-----------REANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKK 3907
R+L+ A Y+ L R+ +D A+ I + + + G DL VE L ++
Sbjct: 2442 WRQLQGALNAYRALLGGANEIHVFNRDVDDTADRIAEKSLAMSSTDTGRDLAAVEALIRR 2501
Query: 3906 FDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXX 3727
+ + D+ A + ++ + A L A I +++E+L+ W L
Sbjct: 2502 EEALERDMSAVKQKIDQHETAAEFLIKKYPERGAQHIERKLEELHKSWGNLQALSVKRQS 2561
Query: 3726 QLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGD 3547
L A+ +F DV E W+ + +++ + + H+ + ++ +
Sbjct: 2562 ILNEAYLAHKFVSDVKELELWVNDMIKKMNNTQSPSTINDCETQLELHQERKVEIEGRQE 2621
Query: 3546 KIKSLDEKANRL----RQSHPEAAEQ----IYDLQRELNEQWNRLTSKANNRKEKLLDSY 3391
L ++ +L +Q P+ + + +L + LNE W + R L +++
Sbjct: 2622 AFAGLKQQGEQLSKRPQQQQPDNVRKYLLVLEELHQTLNEAW-------SERARDLTEAH 2674
Query: 3390 DYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFD 3211
Q F + + W+A+ +++ +L + T E LL++H E+ + A
Sbjct: 2675 QLQLFKAQVEQVEIWLANKEAFLNNDDLGDSYTAVERLLKKHDEFEKLL--HADHVDTLQ 2732
Query: 3210 QFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADT 3031
+F N +L A I +L + ++ L + R+ L Q +LQ F R + D
Sbjct: 2733 KFANSILEGEPKDADLIREKLAYILRRKQKLLELSEERKQRLTQSHQLQEFLRSLYEIDR 2792
Query: 3030 WMSAR-EAFLAQEDPSGDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSP 2854
W+ + + L + N++S I+KH FD + + +++ + E LI+ +H+
Sbjct: 2793 WLVQKLQVALDENYREPSNLQSKIQKHAAFDAELLSNSPRVQSVIHEGERLIRGDHFAKD 2852
Query: 2853 AVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTE-KFQIAQEENY 2677
+ ++ + W LK A K+ KL ++ F+R DE NWM E + Q++ E+
Sbjct: 2853 EIAQQVQLLEGDWLKLKGASQTKKDKLQQAYDALAFNRSVDEFNNWMDEVELQLSSEDYG 2912
Query: 2676 RDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQ 2497
+D + +K + EA++ + + + Q + E + R +
Sbjct: 2913 KDLAAVSNLLKKHERLEADVAHHGELADQLKQKDEQFFQAEHFLRHE--IHERATVSIRR 2970
Query: 2496 WDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKK 2317
++ L + + L+++ + F+ +D WL E +++ S+D G L SV+ L KK
Sbjct: 2971 YNTLHEPLGIRRENLEDSLSLQQFLRDAEDELQWLAEKQLVAGSQDLGTSLLSVQGLQKK 3030
Query: 2316 HSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDK 2137
H+ LEA++ + + + + ++ ++ ++ F +Q+ + +L+ + ++ +A RR +
Sbjct: 3031 HNSLEAELTSQEPLIQALLQRGQQMIRDNHFASEQLQYKSELLQKQLVQLRDLAAIRRLR 3090
Query: 2136 LSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQ 1957
L A+ F+ + ++ ++W++EK+ ++SS DYGRD VQ ++K + EL + +P
Sbjct: 3091 LLDAVESQLFYVEANEADAWMREKRPVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPS 3150
Query: 1956 VSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFL 1777
+ V L+ I ++ + Q + + L R RL E + +L
Sbjct: 3151 IEKVAKLATGLIE---RNHFDSSNIAEKNAQVGQEYEDLLRLAKERESRLGECKKLFEYL 3207
Query: 1776 GDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTL 1597
+ EE W+ ++ + S+++GE++ V+ L+ ++F +L ++ RV + +GD L
Sbjct: 3208 RETEELHEWVGDQMAVTASEDYGEDVEHVEQLILAFESFVSNLNANEARVEACLERGDRL 3267
Query: 1596 IHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKE 1417
I N + IK + D+ + E++ + R L + D I EK+
Sbjct: 3268 IQENNPYRSSIKSKRDETKQLWEELKDLVHARQDALAGAKQVHVYDRVADETIQLINEKD 3327
Query: 1416 QQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEK 1237
+ SED+G+DL S+Q L K + F++ L + + + + +L IE
Sbjct: 3328 ASLISEDYGQDLESIQALGRKHQVFESELVGIQGQ-VDSVLAEAAKLGEIYPDAKEHIEV 3386
Query: 1236 RHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTD 1057
+ ++ W +L + AR+ +E A W +T
Sbjct: 3387 KRDETVEAWTDLKEKTAARKNKLSQAEQLQSYFDEYRDLIA--------WINEMLAKITA 3438
Query: 1056 PVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALE 877
P NS+ L + + + + +E F + +++ F +E
Sbjct: 3439 PELANSVAGAELLLASTKDHDTEIRTRDETFAKFAANGQQLIK-------EKHFLAHEVE 3491
Query: 876 DTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEMMEA--GGT 703
D + LQ + + L + + E N + F K A W+++ ++ + G +
Sbjct: 3492 DKIKVLQARHELLKHTLNKRREIYELNLDTQL-FLKDAEILEQWISSREPQLKDTKLGDS 3550
Query: 702 LEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERNLILDNRY---TEHSTVGIAQAWDQL 532
+ + D + R K Q EEK ++R +L+ + E + Q ++L
Sbjct: 3551 IPQVEDLLRRHEDFEKTVAAQ----EEKFQAIKRITMLEQLFRHQLEQEKISKLQEKERL 3606
Query: 531 --DQLAMRMQHNLEQQIQARNQSGVSEE 454
++L Q L++ R ++ E
Sbjct: 3607 EKERLEQLKQRELQRLADERRRAEKQHE 3634
Score = 511 bits (1316), Expect = e-142
Identities = 471/2295 (20%), Positives = 948/2295 (40%), Gaps = 57/2295 (2%)
Frame = -1
Query: 7212 ILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTA 7033
I E AD + +R+Q + Y ++ +Q + LE++ F R+ D+ W+ EK +
Sbjct: 942 INENADSVEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKERMI 1001
Query: 7032 QEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEEL 6853
+ + N + K +K F ++ A +K + +D + + H + I R ++
Sbjct: 1002 KSDEGEGVDNAKRKFEK---FITDLSAASKRVEEIDGAVDTFRRQGHSQLDKIIARQRQI 1058
Query: 6852 HALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEIL 6673
H +W + L+ A + F R CDE W+ EK + + DL V+ L
Sbjct: 1059 HQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVITPDLRTVQAL 1118
Query: 6672 QRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATR 6493
QR+ + +EL + ++N + + + +E D + ++ +V D W ++ +
Sbjct: 1119 QRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQDMWQQVQQRGSDL 1178
Query: 6492 KEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAAL 6313
+ + Q FN A LAWI L++D+ RD+ L +KH D+ A
Sbjct: 1179 RNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDLGDDIRAH 1238
Query: 6312 EGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFL 6133
+ + +++ + +L++ P+ AE + + KA +A+ ++ L + L F
Sbjct: 1239 DTEFVEVIQLGKQLSDGKPNMAETV-AVIERLKAEQDAIHRGWAEKQKWLLQCVDLQMFN 1297
Query: 6132 ADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKL 5953
+ + + +A + + L + EA+L+ H + + + A+ + KL
Sbjct: 1298 READKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLDFEKSLMAQDKILKGFSDNADKL 1357
Query: 5952 VEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQE 5773
+ +S + ++ ++ ++ ++ ER+ L + D F + + + W+ +
Sbjct: 1358 ISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKT 1417
Query: 5772 AFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEX 5593
+ + D L ++ ++KH+ FE+ L A E ++ + + L+Q + +V
Sbjct: 1418 RIAGDENYRD-LSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQAGN-RVPEVESR 1475
Query: 5592 XXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARD-DSYLDPTN 5416
+G L+++ ++ +R ++ + E S R D D +
Sbjct: 1476 VADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDSALRSGDVGNDLRS 1535
Query: 5415 IRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDA 5236
+ + K E E+ + ++ ++ STG+ + GHF A +I +++ + +L D
Sbjct: 1536 CKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQQRFKDLRDP 1595
Query: 5235 TNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESD 5056
T ++ AKL E+ N +F ++ W++E S + G++L Q+L KK +E++
Sbjct: 1596 TQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKSNELGQNLHQAQSLHKKHKKLEAE 1655
Query: 5055 FNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQG 4876
H ++ Q ++H + + L+Q + L +R RKL S +
Sbjct: 1656 IKGHQPMINKALVAGQSLISQQHPEREQVESLCQQLEQAWQDLERHCGERSRKLDMSLKA 1715
Query: 4875 NQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSA 4696
Q D + +W+ E+ V ST GRD L+ K + + E+ + + + +
Sbjct: 1716 QQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLLTKHKTIELELDTYSGIVTEMGHS 1775
Query: 4695 ANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWM 4516
M+ H + + K + + L A +R+ L +SL H+Y +++E + W+
Sbjct: 1776 CAAMVAANHPDSKVLAAKQQLIEKMLKSLHKLASQRQGRLMESLYKHEYFLESDEVEQWI 1835
Query: 4515 SEKEPIVGSTDYGKDEDSAEALLK-----KHRA----------------LLSDLEAFKGT 4399
E+E S DYG+D + + L KHR L+ +
Sbjct: 1836 REQEQAASSEDYGQDFEHLQLLQNKFDDLKHRVEVGADRVDQCELLAKKLIDSESPYANE 1895
Query: 4398 IEDLRKQ--------ASQCKYQEQPMGQLG------RDCVLALYDYQEKSPREVSMKKGD 4261
+E ++Q +EQ + G RD AL+ Q+K+ +S + G
Sbjct: 1896 VEKRQEQLRTSWENLLQLLNQREQKLHAAGEIHRFHRDVAEALFRIQDKN-AALSQELGR 1954
Query: 4260 VLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIEPGTAQQHAQQQVNSIGGKQSEIEDKYQ 4081
L A R E ND V + Q ++I +Q ++ +
Sbjct: 1955 DLNSALALLRKHEGFE-NDLVALEAQLQVLVEDSVRLQAKYPSNASAIAQQQDKVVAAWN 2013
Query: 4080 RLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFD 3901
L R +L + L + D+ W + A +E +D L+ + D
Sbjct: 2014 DLKERSTARGDRLAASSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHD 2073
Query: 3900 DFKGDLKANEVRLQEMNQIATALTSVGQ------TETAVRIRQQIEDLNARWRALXXXXX 3739
G+++A E + + +N+++ ++ G E + + + L+A W
Sbjct: 2074 AIYGEIEAREDKFRYLNELSDSMVQTGHYAAADVEEKCAAMLDERQKLHAAWN------- 2126
Query: 3738 XXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLA 3559
L ++ F RD + + + AL S DFG+ + VQ RKH+ ER +
Sbjct: 2127 KKKIMLEQKIDLFCFLRDAKQIDNLSSSQQAALSSSDFGQTVEDVQNKIRKHDEFERLIQ 2186
Query: 3558 ALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQR 3379
+K+ L E +L + + I + + + + ++ R+ KL D+ Y +
Sbjct: 2187 TQEEKVSLLQEHGRKLIEQRHYDSANIQTILQGVLARRQKVKDLCAVRRYKLEDALLYAK 2246
Query: 3378 FLSDYRDLMQWI-ASMNQLVSSQELANDVTGAE---ALLERHQEYRTEIDSRAATFQAFD 3211
F+ D + WI +L + +VT + L++HQ ++ E+ + Q
Sbjct: 2247 FVRDCAEAKYWINEKQKKLEADAASYAEVTNLDEKIKKLQKHQAFQAEVAANQGRIQEIQ 2306
Query: 3210 QFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADT 3031
G LL+ H ++ +I+ ++ V EA +GL R L++ + F ++ +
Sbjct: 2307 DTGVILLSKQHESSPEIKRAIEIVLEAWQGLLAELEQRGRGLEEAQDSLEFNSQLDKIEA 2366
Query: 3030 WMSAREAFLAQEDPSGD--NVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHY-- 2863
W+ +E + D D + +L++K +D D + ++++K + A+ LI
Sbjct: 2367 WIRDKEMMVQASDTGRDLEHCNALMRKLDDVDSDMRVDDQRVKHINQLADKLINQAQVPA 2426
Query: 2862 DSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEK-FQIAQE 2686
D+ +V ++R W L+ AL R LG + + F+RD D+ + + EK ++
Sbjct: 2427 DTQSVDKRRKDFNYNWRQLQGALNAYRALLGGANEIHVFNRDVDDTADRIAEKSLAMSST 2486
Query: 2685 ENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKAL 2506
+ RD ++ ++++A E ++ A +I A LI+ G + + +L+ L
Sbjct: 2487 DTGRDLAAVEALIRREEALERDMSAVKQKIDQHETAAEFLIKKYPERGAQ-HIERKLEEL 2545
Query: 2505 NDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENL 2326
+ W L + ++ L EA F++ VK+LE W+ ++ + + + E
Sbjct: 2546 HKSWGNLQALSVKRQSILNEAYLAHKFVSDVKELELWVNDMIKKMNNTQSPSTINDCETQ 2605
Query: 2325 LKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADR-YDGVKKMATD 2149
L+ H + +I Q+ + +Q + L + Q Q + L+ + + + + ++
Sbjct: 2606 LELHQERKVEIEGRQEAFAGLKQQGEQLSKRPQQQQPDNVRKYLLVLEELHQTLNEAWSE 2665
Query: 2148 RRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELAS 1969
R L++A + F ++ E W+ K+ +++DD G V+ L +KH + L
Sbjct: 2666 RARDLTEAHQLQLFKAQVEQVEIWLANKEAFLNNDDLGDSYTAVERLLKKHDEFEKLL-- 2723
Query: 1968 HEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAF 1789
H V ++ +L + D I++++ + + ++ +L+ R QRL +S
Sbjct: 2724 HADHVDTLQKFANSILEGEPK---DADLIREKLAYILRRKQKLLELSEERKQRLTQSHQL 2780
Query: 1788 QAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINK 1609
Q FL + E + W+ +K Q+ +N+ E + +Q ++KH F +L + RV +I++
Sbjct: 2781 QEFLRSLYEIDRWLVQKLQVALDENYRE-PSNLQSKIQKHAAFDAELLSNSPRVQSVIHE 2839
Query: 1608 GDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWI 1429
G+ LI + I Q+ L ++++ ++ + KL+ L F D +W+
Sbjct: 2840 GERLIRGDHFAKDEIAQQVQLLEGDWLKLKGASQTKKDKLQQAYDALAFNRSVDEFNNWM 2899
Query: 1428 AEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSP 1249
E E Q+ SED+G+DL++V LL K E +A + A E ++ + +Q +EH
Sbjct: 2900 DEVELQLSSEDYGKDLAAVSNLLKKHERLEADV-AHHGELADQLKQKDEQFFQAEHFLRH 2958
Query: 1248 AIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEE 1069
I +R T I+R+ L RR F + A W +
Sbjct: 2959 EIHERATVSIRRYNTLHEPLGIRRENLEDSLSLQ--------QFLRDAEDELQWLAEKQL 3010
Query: 1068 DLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTM 889
SL ++ L+ H + L+S E + L +++ N + +
Sbjct: 3011 VAGSQDLGTSLLSVQGLQKKHNSLEAELTSQEPLIQALLQRGQQMIRDNHFASEQLQYKS 3070
Query: 888 DALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEMMEAG 709
+ L+ L+ + R L + Q F AN AW+ R + +
Sbjct: 3071 ELLQKQLVQLRDLAAIRRLRLLDAVESQ--------LFYVEANEADAWMREKRPVLSSSD 3122
Query: 708 -GTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERNLILDNRYTE----HSTVGIAQA 544
G E + ++K + ++ + EK A L LI N + + Q
Sbjct: 3123 YGRDEVSVQGHQKKLEVLQRELTAFKPSIEKVAKLATGLIERNHFDSSNIAEKNAQVGQE 3182
Query: 543 WDQLDQLAMRMQHNL 499
++ L +LA + L
Sbjct: 3183 YEDLLRLAKERESRL 3197
Score = 503 bits (1294), Expect = e-140
Identities = 491/2306 (21%), Positives = 986/2306 (42%), Gaps = 133/2306 (5%)
Frame = -1
Query: 7119 RLEEARQFQY-FKRDADELNVWILEKLQTAQEENFRDPSNLQAKIQKHEAFEAEVQAHAK 6943
R E+ Q Y F++ + ++ E +Q + + + A ++KHEA A++ A +
Sbjct: 390 RQEKLEQLNYKFEKKSVLREGYLKEMIQVLSDPRYL--RQVDATLKKHEAISADILARVE 447
Query: 6942 TIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQ 6763
+L + + N+ E +++R +E+ A W + + L Q L++ +R+
Sbjct: 448 RFNDLTAMAEELDRENYHGKERVRRREQEVMAKWRQLLELLENQRLNLSQMSNLMNLLRE 507
Query: 6762 CDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQY--RINEINQAADKL 6589
+RE + +ED+G L VE L + L+EL + Y + N+ A
Sbjct: 508 IASTTEAVRELQQQFASEDVGPHLLGVEELLQAHS--LQELQVNTYGETLKRFNRQALPY 565
Query: 6588 VEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKD 6409
H + + ++ D+ +A+ L +A R+ L A F D D +W+ +K
Sbjct: 566 KSSEHKDAALLAQRLADLEEAYSELLRRSAARRARLEEARNFHHFMEDYDNEESWLVDKQ 625
Query: 6408 LALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKL-AETHPDRAEAIHQ 6232
+ +DL V +LQ+KH+ E ++ + + K Q+ +L E HP R+ I
Sbjct: 626 RICKTGITAKDLRAVLSLQQKHKALEDEIKSRKPKSGQMSTAGKRLIGEQHP-RSSEIQS 684
Query: 6231 KNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVA 6052
+ D W AL+ + R+ LE + + ++F D + SW+ + A++ + + D
Sbjct: 685 RIDSLAEHWQALEALVELRRRQLEDAAEAYQFYTDANEAESWLNEKIALVNSRDYGNDEP 744
Query: 6051 GAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGI---------PESPEVQEK---- 5911
A+ALL+ H++ +GE++A + KL++ GI PE PEV+++
Sbjct: 745 SAQALLQRHRDLQGELNAYSGDILNLNQQADKLIKAGICTLELSAAEPELPEVEQEEWVN 804
Query: 5910 --------------LEKLDHEKSSLLGLWEERRILYE---QCMDLQ----LFYRDTEQAE 5794
+EKL+H+K + + + L+ Q M + + + +
Sbjct: 805 ETRLVPKEVWEDEWVEKLEHKKVTETKMLPHVKSLFPFEGQGMKMDKGEVMLLKSKTNDD 864
Query: 5793 TWMNKQEAFLANTDLGDSLDSVE-----------HLIKKHEDFEKSLAAQE----EKINA 5659
W +++ + + + VE +K + +K++ ++ ++I
Sbjct: 865 WWCVRKDNGVEGFVPANYVREVEPRPVACIVPKAEKVKSLQKVKKTILVRQVVPVKRIKP 924
Query: 5658 LDEFATKLIQGQ------HYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFD 5497
+ L+Q + + AD V + R L++S F
Sbjct: 925 VSVAPKPLVQRRTSTQSINENADSVEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFY 984
Query: 5496 RDCDEMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQII 5317
R+CD+ W+ EK + D N + K +K I +L A R+++I +
Sbjct: 985 RECDDFEKWMKEKERMIKSDEGEGVDNAKRKFEKFIT---DLSAASKRVEEIDGAVDTFR 1041
Query: 5316 DSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEG 5137
GH D I R RQ++ +W L +A ++ L A + + FNR ++ + W+SE
Sbjct: 1042 RQGHSQLDKIIARQRQIHQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKML 1101
Query: 5136 QVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQ-----EEEHFNAPV 4972
Q+ + DL +VQ LQ++ +E + D+V+ + L + E+++ NA
Sbjct: 1102 QLDTAVITPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNA-- 1159
Query: 4971 IVRKQE------NLQQRYNALRDPLEKRKRKLGESHQGNQLFRD-IEDELAWIREKEQVA 4813
R+QE +QQR + LR+ + ES G Q+F + + LAWI +
Sbjct: 1160 --RQQEVQDMWQQVQQRGSDLRNRI--------ESEVGQQVFNNSAKVLLAWIDSVKDQL 1209
Query: 4812 GSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLA---PEIRDK 4642
+ RD+ NL+KK L +I HD++ V IQ G L+ P + +
Sbjct: 1210 NADESARDVETANNLLKKHNDLGDDIRAHDTEFVEV-------IQLGKQLSDGKPNMAET 1262
Query: 4641 LAQLR----DNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGK 4474
+A + + I + AEK++ L + + +A++ DA E + + G
Sbjct: 1263 VAVIERLKAEQDAIHRGWAEKQKW-LLQCVDLQMFNREADKIDATTKSHEAFLEYNNLGA 1321
Query: 4473 DEDSAEALLKKH----RALLSDLEAFKGTIEDLRKQASQCKYQEQPMGQLGRDCVL---- 4318
D EA+LK+H ++L++ + KG ++ K S Y + +G R+ VL
Sbjct: 1322 SLDEVEAILKRHLDFEKSLMAQDKILKGFSDNADKLISNDHYDSKYIGD-RRNQVLGKRK 1380
Query: 4317 ALYDYQEKSPREVSMKKGDVLTLLNASNRDWW---KVEVNDRQGFVPAAYVKR------- 4168
A+ D + R + K A + W K + + + + + R
Sbjct: 1381 AVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKTRIAGDENYRDLSNLPRKLQKHQA 1440
Query: 4167 ---------------IEPGTAQQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEA 4033
+ G A A +V + + +++ +++ L+ L E + RKLE+A
Sbjct: 1441 FERELRANEGQLRNVTKDGQALVQAGNRVPEVESRVADLNKRWKDLLTLSEDKGRKLEQA 1500
Query: 4032 CKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEM 3853
+ R D + + ++ ++G DL + L K + ++ + ++ E+
Sbjct: 1501 ASQREHNRSLEDAKKKVDELDSALRSGDVGNDLRSCKDLINKQQILESEITIWDQKVAEL 1560
Query: 3852 NQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDET 3673
+ G A I ++L R++ L +L + +F ++D
Sbjct: 1561 VSTGDDMAHGGHF-NAQNIEAGTKELQQRFKDLRDPTQRRRAKLEESLNYHKFVFELDSE 1619
Query: 3672 RDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKI-KSLDEKANRLRQSHP 3496
WI E A S + G++L Q+L +KH+ +E ++ I K+L + + Q HP
Sbjct: 1620 FQWINEHLPAAKSNELGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALVAGQSLISQQHP 1679
Query: 3495 EAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSS 3316
E EQ+ L ++L + W L R KL S Q++L D ++ W+ N ++ S
Sbjct: 1680 E-REQVESLCQQLEQAWQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERNNVLRS 1738
Query: 3315 QELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVN 3136
E D A LL +H+ E+D+ + ++ ++H + + + Q +
Sbjct: 1739 TEYGRDRDSAAKLLTKHKTIELELDTYSGIVTEMGHSCAAMVAANHPDSKVLAAKQQLIE 1798
Query: 3135 EARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGD--NVESLI 2962
+ K L R+ L + L ++ + ++ + W+ +E + ED D +++ L
Sbjct: 1799 KMLKSLHKLASQRQGRLMESLYKHEYFLESDEVEQWIREQEQAASSEDYGQDFEHLQLLQ 1858
Query: 2961 KKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKR 2782
K +D + +++ +L A+ LI + + V ++++Q+ W L + L Q+
Sbjct: 1859 NKFDDLKHRVEVGADRVDQCELLAKKLIDSESPYANEVEKRQEQLRTSWENLLQLLNQRE 1918
Query: 2781 FKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHANSD 2602
KL + + +F RD E + +K +E RD + +K + FE +L A
Sbjct: 1919 QKLHAAGEIHRFHRDVAEALFRIQDKNAALSQELGRDLNSALALLRKHEGFENDLVALEA 1978
Query: 2601 RIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFM 2422
++ +++ L AK +A++ + + W+ L + +T + RL ++ ++F+
Sbjct: 1979 QLQVLVEDSVRL--QAKYPSNASAIAQQQDKVVAAWNDLKERSTARGDRLAASSDLQTFL 2036
Query: 2421 AAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSL 2242
V+D+ W + LQ+E++ D A L +H + +I A +D+ +NE +DS+
Sbjct: 2037 TDVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEAREDKFRYLNELSDSM 2096
Query: 2241 LENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKK 2062
++ + + E+ + D + ++ L + +++ F RD ++ ++
Sbjct: 2097 VQTGHYAAADVEEKCAAMLDERQKLHAAWNKKKIMLEQKIDLFCFLRDAKQIDNLSSSQQ 2156
Query: 2061 LLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQI 1882
+SS D+G+ + VQN RKH + + + E +VSL++ G +L+ + I
Sbjct: 2157 AALSSSDFGQTVEDVQNKIRKHDEFERLIQTQEEKVSLLQEHGRKLIE---QRHYDSANI 2213
Query: 1881 KKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSD--NFG 1708
+ ++ + +++DL R +L+++ + F+ D E + W+NEKQ+ L +D ++
Sbjct: 2214 QTILQGVLARRQKVKDLCAVRRYKLEDALLYAKFVRDCAEAKYWINEKQKKLEADAASYA 2273
Query: 1707 E--NMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQL--- 1543
E N+ L+KH FQ ++ ++ R+ ++ + G L+ + +P IK+ + +
Sbjct: 2274 EVTNLDEKIKKLQKHQAFQAEVAANQGRIQEIQDTGVILLSKQHESSPEIKRAIEIVLEA 2333
Query: 1542 -RARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQI 1366
+ L E+E G L + L+F + D +E+WI +KE V++ D GRDL
Sbjct: 2334 WQGLLAELEQRGRG----LEEAQDSLEFNSQLDKIEAWIRDKEMMVQASDTGRDLEHCNA 2389
Query: 1365 LLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEH--QQSPAIEKRHTNVIQRWQNLLAH 1192
L+ K + D+ + + + ++ I +L D+L++ + +++KR + W+ L
Sbjct: 2390 LMRKLDDVDSDMRV-DDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYNWRQLQGA 2448
Query: 1191 SEARRX---XXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRA 1021
A R +++ A+K+ +S TD R L + A
Sbjct: 2449 LNAYRALLGGANEIHVFNRDVDDTADRIAEKSLAMSS---------TDTGR--DLAAVEA 2497
Query: 1020 LRDAHGEFQRSLSSAEEDFRQLQD-LDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIK 844
L +R +S+ ++ Q + + IK + + ++ L +W NLQ +
Sbjct: 2498 LIRREEALERDMSAVKQKIDQHETAAEFLIKKYPERGAQHIERKLEELHKSWGNLQALSV 2557
Query: 843 EREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEM--MEAGGTL---EEQLDAV 679
+R+ L + L +F W+ + ++M ++ T+ E QL+
Sbjct: 2558 KRQSILNEAY--------LAHKFVSDVKELELWVNDMIKKMNNTQSPSTINDCETQLELH 2609
Query: 678 ERKAKEIKANKGQLRQIEEKGAMLER 601
+ + EI+ + ++++G L +
Sbjct: 2610 QERKVEIEGRQEAFAGLKQQGEQLSK 2635
Score = 455 bits (1170), Expect = e-126
Identities = 455/2234 (20%), Positives = 916/2234 (40%), Gaps = 59/2234 (2%)
Frame = -1
Query: 7185 QRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQ----EENF 7018
QR ++ YS S +R RLEEAR F +F D D W+++K + + ++
Sbjct: 578 QRLADLEEAYSELLRRSAARRARLEEARNFHHFMEDYDNEESWLVDKQRICKTGITAKDL 637
Query: 7017 RDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWX 6838
R +LQ QKH+A E E+++ + G +I H S I+ R++ L W
Sbjct: 638 RAVLSLQ---QKHKALEDEIKSRKPKSGQMSTAGKRLIGEQHPRSSEIQSRIDSLAEHWQ 694
Query: 6837 XXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFD 6658
+ +L+ A + F +E W+ EK V + D G D + L ++
Sbjct: 695 ALEALVELRRRQLEDAAEAYQFYTDANEAESWLNEKIALVNSRDYGNDEPSAQALLQRHR 754
Query: 6657 DFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLF 6478
D EL + I +NQ ADKL++ G + TL + E
Sbjct: 755 DLQGELNAYSGDILNLNQQADKLIKAG--------------------ICTLELSAAEP-- 792
Query: 6477 GAHQVQRFNRDADETLAWIGEKDLA---LSSDDYGRDLNNVQALQRKHEGTERDLAALEG 6307
E W+ E L + D++ L + + + K + L EG
Sbjct: 793 --------ELPEVEQEEWVNETRLVPKEVWEDEWVEKLEHKKVTETKMLPHVKSLFPFEG 844
Query: 6306 KMLQLEK-EAHKLAETHPDRAEAIHQKND-DTKAAWNALKEKAQHRKDGLERSFQLHRFL 6133
+ ++++K E L D + + N + N ++E + + + L
Sbjct: 845 QGMKMDKGEVMLLKSKTNDDWWCVRKDNGVEGFVPANYVREVEPRPVACIVPKAEKVKSL 904
Query: 6132 ADYRD--LISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQ 5959
+ L+ + +K + K + +S E+ ++ R NQT
Sbjct: 905 QKVKKTILVRQVVPVKRIKPVSVAPKPLVQRRTSTQSINENADSVEKRQQRINQTYD--- 961
Query: 5958 KLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNK 5779
E+QE +K R L E + L FYR+ + E WM +
Sbjct: 962 -----------ELQEMAQK--------------RHALLEDSIHLFGFYRECDDFEKWMKE 996
Query: 5778 QEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVA 5599
+E + +D G+ +D+ + +K E F L+A +++ +D + H D +
Sbjct: 997 KERMI-KSDEGEGVDNAK---RKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDKII 1052
Query: 5598 EXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDP- 5422
R +L+ + + F+R CDE W++EK+ D + + P
Sbjct: 1053 ARQRQIHQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKM-LQLDTAVITPD 1111
Query: 5421 -TNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNEL 5245
++ ++H N E+EL E++++ + G + ++ D++ R ++V ++W ++
Sbjct: 1112 LRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQDMWQQV 1171
Query: 5244 VDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLI 5065
+ ++ +Q FN + + + AW+ ++ Q+ +++ +D+ + NL KK +
Sbjct: 1172 QQRGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDL 1231
Query: 5064 ESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGES 4885
D AH+ + QL +Q + + N V E L+ +A+ ++++ L +
Sbjct: 1232 GDDIRAHDTEFVEVIQLGKQLSDGKP-NMAETVAVIERLKAEQDAIHRGWAEKQKWLLQC 1290
Query: 4884 HQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESV 4705
R+ + A + E N G L V+ ++K+ + D ++
Sbjct: 1291 VDLQMFNREADKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLDFEKSLMAQDKILKGF 1350
Query: 4704 SSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEAD 4525
S A+ +I H+ + I D+ Q+ + +K +A +R+ L S H++ ++A++
Sbjct: 1351 SDNADKLISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEADDLK 1410
Query: 4524 AWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQA---------- 4375
W+ +K I G +Y +D + L+KH+A +L A +G + ++ K
Sbjct: 1411 VWLQDKTRIAGDENY-RDLSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQAGNRV 1469
Query: 4374 --------------------SQCKYQEQPMGQLGRDCVLALYDYQEK-SPREVSMKKGDV 4258
S+ K ++ R+ +L D ++K + +++ GDV
Sbjct: 1470 PEVESRVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDSALRSGDV 1529
Query: 4257 LTLLNASNRDWWKVEVNDRQGFV-PAAYVKRIEPGTAQQHAQQ-QVNSIGGKQSEIEDKY 4084
L + K ++ + + + + + G H +I E++ ++
Sbjct: 1530 GNDLRSCKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQQRF 1589
Query: 4083 QRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKF 3904
+ L + R+ KLEE+ ++ + E + +WI A E+G +L Q + L KK
Sbjct: 1590 KDLRDPTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKSNELGQNLHQAQSLHKKH 1649
Query: 3903 DDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQ 3724
+ ++K ++ + + +L S E ++ + L W+ L +
Sbjct: 1650 KKLEAEIKGHQPMINKALVAGQSLISQQHPERE-QVESLCQQLEQAWQDLERHCGERSRK 1708
Query: 3723 LGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDK 3544
L + + Q++ D E W+ E+++ L S ++GRD S L KH+ +E +L
Sbjct: 1709 LDMSLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLLTKHKTIELELDTYSGI 1768
Query: 3543 IKSLDEK-ANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSD 3367
+ + A + +HP+ ++ + Q+ + + L A+ R+ +L++S + +
Sbjct: 1769 VTEMGHSCAAMVAANHPD-SKVLAAKQQLIEKMLKSLHKLASQRQGRLMESLYKHEYFLE 1827
Query: 3366 YRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLN 3187
++ QWI Q SS++ D + L + + + ++ A + +L++
Sbjct: 1828 SDEVEQWIREQEQAASSEDYGQDFEHLQLLQNKFDDLKHRVEVGADRVDQCELLAKKLID 1887
Query: 3186 SHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAF 3007
S A ++E R + + + + L R L E+ F+RD +A + + A
Sbjct: 1888 SESPYANEVEKRQEQLRTSWENLLQLLNQREQKLHAAGEIHRFHRDVAEALFRIQDKNAA 1947
Query: 3006 LAQE-DPSGDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQ 2830
L+QE ++ +L++KHE F+ + E +++ L + L ++ A+ +++D+
Sbjct: 1948 LSQELGRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSVRLQAKYPSNASAIAQQQDK 2007
Query: 2829 ILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTE-KFQIAQEENYRDPTNIQQ 2653
++ WN LKE + +L S LQ F D +I +W + + + EE+ D
Sbjct: 2008 VVAAWNDLKERSTARGDRLAASSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAGATA 2067
Query: 2652 KHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTT 2473
+ A E+ A D+ + + +++++ A V + A+ D+ L
Sbjct: 2068 LKIQHDAIYGEIEAREDKFRYLNELSDSMVQTGHYAA--ADVEEKCAAMLDERQKLHAAW 2125
Query: 2472 TEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADI 2293
+K L++ F+ K ++ + L S D+G+ + V+N ++KH E I
Sbjct: 2126 NKKKIMLEQKIDLFCFLRDAKQIDNLSSSQQAALSSSDFGQTVEDVQNKIRKHDEFERLI 2185
Query: 2292 VAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVH 2113
+++V + E L+E + I + + R VK + RR KL AL
Sbjct: 2186 QTQEEKVSLLQEHGRKLIEQRHYDSANIQTILQGVLARRQKVKDLCAVRRYKLEDALLYA 2245
Query: 2112 QFFRDIDDEESWI--KEKKLLVSSDDYGRDLPGVQNLRR--KHRRIDTELASHEPQVSLV 1945
+F RD + + WI K+KKL + Y + +++ KH+ E+A+++ ++ +
Sbjct: 2246 KFVRDCAEAKYWINEKQKKLEADAASYAEVTNLDEKIKKLQKHQAFQAEVAANQGRIQEI 2305
Query: 1944 KLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVE 1765
+ G LL E+ +IK+ +E + ++W + R + L+E++ F ++
Sbjct: 2306 QDTGVILLSKQHES---SPEIKRAIEIVLEAWQGLLAELEQRGRGLEEAQDSLEFNSQLD 2362
Query: 1764 EEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNG 1585
+ EAW+ +K+ ++ + + G ++ L++K D D+ + QRV + D LI+
Sbjct: 2363 KIEAWIRDKEMMVQASDTGRDLEHCNALMRKLDDVDSDMRVDDQRVKHINQLADKLINQA 2422
Query: 1584 NHHA--PHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQ 1411
A + +R +++ A L + F D IAEK
Sbjct: 2423 QVPADTQSVDKRRKDFNYNWRQLQGALNAYRALLGGANEIHVFNRDVDDTADRIAEKSLA 2482
Query: 1410 VRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRH 1231
+ S D GRDL++V+ L+ ++EA + ++A + + Q T + + + + IE++
Sbjct: 2483 MSSTDTGRDLAAVEALIRREEALERDMSAVKQKIDQHETAAEFLIKKYPERGAQHIERKL 2542
Query: 1230 TNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLA--FAKKASTFNSWFENAEEDLTD 1057
+ + W NL A S R+ + E YLA F W + + + +
Sbjct: 2543 EELHKSWGNLQALSVKRQ----------SILNEAYLAHKFVSDVKELELWVNDMIKKMNN 2592
Query: 1056 PVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRI--KSFNVGPNPYTWFTMDA 883
+++ + + H E + + +E F L+ ++ + P+ + +
Sbjct: 2593 TQSPSTINDCETQLELHQERKVEIEGRQEAFAGLKQQGEQLSKRPQQQQPDNVRKYLL-V 2651
Query: 882 LEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEMMEAGGT 703
LE+ + L ER ++L HQ Q F WL N +E
Sbjct: 2652 LEELHQTLNEAWSERARDLTEAHQLQ--------LFKAQVEQVEIWLAN--KEAFLNNDD 2701
Query: 702 LEEQLDAVERKAKE 661
L + AVER K+
Sbjct: 2702 LGDSYTAVERLLKK 2715
Score = 328 bits (840), Expect = 2e-87
Identities = 188/525 (35%), Positives = 297/525 (55%), Gaps = 2/525 (0%)
Frame = -1
Query: 7224 QEIRILETADDIHQRRQEVLGHYSI-FKDHSQTKRDRLEEARQFQYFKRDADELNVWILE 7048
Q IR A + Q + E+L + +D + +R RL +A + Q F +A+E + W+ E
Sbjct: 3054 QMIRDNHFASEQLQYKSELLQKQLVQLRDLAAIRRLRLLDAVESQLFYVEANEADAWMRE 3113
Query: 7047 KLQTAQEENF-RDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIK 6871
K ++ RD ++Q +K E + E+ A +I + K +I+ NHF S +I
Sbjct: 3114 KRPVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPSIEKVAKLATGLIERNHFDSSNIA 3173
Query: 6870 KRLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDL 6691
++ ++ + + +L + KL ++R+ +E+ W+ ++ +ED G D+
Sbjct: 3174 EKNAQVGQEYEDLLRLAKERESRLGECKKLFEYLRETEELHEWVGDQMAVTASEDYGEDV 3233
Query: 6690 EHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLN 6511
EHVE L F+ F+ L ++ R+ + D+L++E + I KRD+ W L
Sbjct: 3234 EHVEQLILAFESFVSNLNANEARVEACLERGDRLIQENNPYRSSIKSKRDETKQLWEELK 3293
Query: 6510 TLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTE 6331
L R++ L GA QV ++R ADET+ I EKD +L S+DYG+DL ++QAL RKH+ E
Sbjct: 3294 DLVHARQDALAGAKQVHVYDRVADETIQLINEKDASLISEDYGQDLESIQALGRKHQVFE 3353
Query: 6330 RDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSF 6151
+L ++G++ + EA KL E +PD E I K D+T AW LKEK RK+ L ++
Sbjct: 3354 SELVGIQGQVDSVLAEAAKLGEIYPDAKEHIEVKRDETVEAWTDLKEKTAARKNKLSQAE 3413
Query: 6150 QLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTA 5971
QL + +YRDLI+WI +M A I A ELA VAGAE LL S ++H EI R ++F + A
Sbjct: 3414 QLQSYFDEYRDLIAWINEMLAKITAPELANSVAGAELLLASTKDHDTEIRTRDETFAKFA 3473
Query: 5970 SAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAET 5791
+ GQ+L++ + EV++K++ L L +RR +YE +D QLF +D E E
Sbjct: 3474 ANGQQLIKEKHFLAHEVEDKIKVLQARHELLKHTLNKRREIYELNLDTQLFLKDAEILEQ 3533
Query: 5790 WMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINAL 5656
W++ +E L +T LGDS+ VE L+++HEDFEK++AAQEEK A+
Sbjct: 3534 WISSREPQLKDTKLGDSIPQVEDLLRRHEDFEKTVAAQEEKFQAI 3578
Score = 313 bits (802), Expect = 4e-83
Identities = 227/909 (24%), Positives = 428/909 (46%), Gaps = 5/909 (0%)
Frame = -1
Query: 7200 ADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEEN 7021
AD I ++ +L + S+ ++ RL ++ Q Q F R E++ W+++KLQ A +EN
Sbjct: 2746 ADLIREKLAYILRRKQKLLELSEERKQRLTQSHQLQEFLRSLYEIDRWLVQKLQVALDEN 2805
Query: 7020 FRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALW 6841
+R+PSNLQ+KIQKH AF+AE+ +++ + ++ G +I+ +HFA + I ++++ L W
Sbjct: 2806 YREPSNLQSKIQKHAAFDAELLSNSPRVQSVIHEGERLIRGDHFAKDEIAQQVQLLEGDW 2865
Query: 6840 XXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKF 6661
K KLQQA L F R DE W+ E E +++ED G DL V L +K
Sbjct: 2866 LKLKGASQTKKDKLQQAYDALAFNRSVDEFNNWMDEVELQLSSEDYGKDLAAVSNLLKKH 2925
Query: 6660 DDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGL 6481
+ ++ +H +++ Q ++ + H +I+++ ++ L+ R+E L
Sbjct: 2926 ERLEADVAHHGELADQLKQKDEQFFQAEHFLRHEIHERATVSIRRYNTLHEPLGIRRENL 2985
Query: 6480 FGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKM 6301
+ +Q+F RDA++ L W+ EK L S D G L +VQ LQ+KH E +L + E +
Sbjct: 2986 EDSLSLQQFLRDAEDELQWLAEKQLVAGSQDLGTSLLSVQGLQKKHNSLEAELTSQEPLI 3045
Query: 6300 LQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYR 6121
L + ++ + +E + K++ + L++ A R+ L + + F +
Sbjct: 3046 QALLQRGQQMIRDNHFASEQLQYKSELLQKQLVQLRDLAAIRRLRLLDAVESQLFYVEAN 3105
Query: 6120 DLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMG 5941
+ +W+ + + V+ + + +D + + + + E+ A S + A L+E
Sbjct: 3106 EADAWMREKRPVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPSIEKVAKLATGLIERN 3165
Query: 5940 IPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLA 5761
+S + EK ++ E LL L +ER +C L + R+TE+ W+ Q A A
Sbjct: 3166 HFDSSNIAEKNAQVGQEYEDLLRLAKERESRLGECKKLFEYLRETEELHEWVGDQMAVTA 3225
Query: 5760 NTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXX 5581
+ D G+ ++ VE LI E F +L A E ++ A E +LIQ + +
Sbjct: 3226 SEDYGEDVEHVEQLILAFESFVSNLNANEARVEACLERGDRLIQENNPYRSSIKSKRDET 3285
Query: 5580 XXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEK-LSTARDDSYLDPTNIRGK 5404
R +AL + + +DR DE + I EK S +D D +I+
Sbjct: 3286 KQLWEELKDLVHARQDALAGAKQVHVYDRVADETIQLINEKDASLISEDYGQDLESIQAL 3345
Query: 5403 LQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKK 5224
+KH FE EL + ++D + + ++ + A +HI + + W +L + T +
Sbjct: 3346 GRKHQVFESELVGIQGQVDSVLAEAAKLGEIYPDAKEHIEVKRDETVEAWTDLKEKTAAR 3405
Query: 5223 GAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAH 5044
KL +A Q + D+ AW++E+ ++ + + + + L +++
Sbjct: 3406 KNKLSQAEQLQSYFDEYRDLIAWINEMLAKITAPELANSVAGAELLLASTKDHDTEIRTR 3465
Query: 5043 NDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLF 4864
++ QQ +E+HF A + K + LQ R+ L+ L KR R++ E + QLF
Sbjct: 3466 DETFAKFAANGQQLIKEKHFLAHEVEDKIKVLQARHELLKHTLNKR-REIYELNLDTQLF 3524
Query: 4863 -RDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAAND 4687
+D E WI +E T G + V++L+++ + +A + + +++
Sbjct: 3525 LKDAEILEQWISSREPQLKDTKLGDSIPQVEDLLRRHEDFEKTVAAQEEKFQAIKRIT-- 3582
Query: 4686 MIQQGHFLAPEIRDKLAQLRDNWRILKSKAEK-RRTDLDDSLQAHQYLSDANE--ADAWM 4516
M++Q F ++K+++L++ R+ K + E+ ++ +L + +E +A
Sbjct: 3583 MLEQ-LFRHQLEQEKISKLQEKERLEKERLEQLKQRELQRLADERRRAEKQHEHRQNAAS 3641
Query: 4515 SEKEPIVGS 4489
EK PI S
Sbjct: 3642 QEKTPIFSS 3650
Score = 219 bits (557), Expect = 1e-54
Identities = 252/1272 (19%), Positives = 506/1272 (38%), Gaps = 86/1272 (6%)
Frame = -1
Query: 3999 DLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQ-----IATA 3835
+L WI+ + Q+++ LE ++ F +++ K + + + + I T
Sbjct: 287 NLLSWIRQKTLELEQRDLPNSLEGIQRELLAFKEYRTIEKPPKYKERSEIEALYFTINTL 346
Query: 3834 LTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQ--------RFHRDVD 3679
L ++ Q + Q + D+ W+ L L Q +F +
Sbjct: 347 LKALNQPPYNPQDGQLVNDIEKAWQILEYAEHHREVALRDELLRQEKLEQLNYKFEKKSV 406
Query: 3678 ETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSH 3499
+++E L R LR V A +KHE + D+ A ++ L A L + +
Sbjct: 407 LREGYLKEMIQVLSDP---RYLRQVDATLKKHEAISADILARVERFNDLTAMAEELDREN 463
Query: 3498 PEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVS 3319
E++ ++E+ +W +L N++ L + L + + + + Q +
Sbjct: 464 YHGKERVRRREQEVMAKWRQLLELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQFA 523
Query: 3318 SQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGV 3139
S+++ + G E LL+ H ++++ T + F++ +S H A + RL +
Sbjct: 524 SEDVGPHLLGVEELLQAHSLQELQVNTYGETLKRFNRQALPYKSSEHKDAALLAQRLADL 583
Query: 3138 NEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGD--NVESL 2965
EA L ARR L++ F D + ++W+ ++ + D V SL
Sbjct: 584 EEAYSELLRRSAARRARLEEARNFHHFMEDYDNEESWLVDKQRICKTGITAKDLRAVLSL 643
Query: 2964 IKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQK 2785
+KH+ + I +++ K + + LI H S + + D + + W L+ + +
Sbjct: 644 QQKHKALEDEIKSRKPKSGQMSTAGKRLIGEQHPRSSEIQSRIDSLAEHWQALEALVELR 703
Query: 2784 RFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENY-RDPTNIQQKHQKQQAFEAELHAN 2608
R +L ++ QF DA+E E+W+ EK + +Y D + Q Q+ + + EL+A
Sbjct: 704 RRQLEDAAEAYQFYTDANEAESWLNEKIALVNSRDYGNDEPSAQALLQRHRDLQGELNAY 763
Query: 2607 SDRIAAIIQAGNNLIENAKCGGGEAAVSARL-----------------KALNDQW----- 2494
S I + Q + LI+ C +A L + D+W
Sbjct: 764 SGDILNLNQQADKLIKAGICTLELSAAEPELPEVEQEEWVNETRLVPKEVWEDEWVEKLE 823
Query: 2493 -------------------------------DLLVKTTTEKSYRLKEANKQKSFMAAVKD 2407
LL T + + +++ N + F+ A
Sbjct: 824 HKKVTETKMLPHVKSLFPFEGQGMKMDKGEVMLLKSKTNDDWWCVRKDNGVEGFVPANYV 883
Query: 2406 LEFWLGEVEILLQSEDYGKDLASVENLL-----------KKHSLLEADIVAHQDRVGEMN 2260
E V ++ + K L V+ + K S+ +V + +N
Sbjct: 884 REVEPRPVACIVPKAEKVKSLQKVKKTILVRQVVPVKRIKPVSVAPKPLVQRRTSTQSIN 943
Query: 2259 EQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEES 2080
E ADS + +R++ I YD +++MA R L ++++ F+R+ DD E
Sbjct: 944 ENADS-----------VEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEK 992
Query: 2079 WIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAG 1900
W+KEK+ ++ SD+ GV N +RK + T+L++ +V + + R
Sbjct: 993 WMKEKERMIKSDEG----EGVDNAKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQ- 1047
Query: 1899 VGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGS 1720
D+I R + Q W ++ + R + L+ + + + F +E + WM+EK L +
Sbjct: 1048 --LDKIIARQRQIHQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDT 1105
Query: 1719 DNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLR 1540
++ VQ L ++H + +L + +V + G+++ + ++ R +++
Sbjct: 1106 AVITPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQ 1165
Query: 1539 ARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILL 1360
+++ ++ F V+ +WI + Q+ +++ RD+ + LL
Sbjct: 1166 DMWQQVQQRGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLL 1225
Query: 1359 TKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEAR 1180
K + A + E ++ + +L QL + + + VI+R L A +A
Sbjct: 1226 KKHNDLGDDIRAHDTEFVE-VIQLGKQLSDGKPNMAETVA-----VIER---LKAEQDAI 1276
Query: 1179 RXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGE 1000
Q +L + F ++A ++ ++ E L SL+E+ A+ H +
Sbjct: 1277 HRGWAEKQKWLLQCVDLQM-FNREADKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLD 1335
Query: 999 FQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAR 820
F++SL + ++ + D ++ S + + Y + + ++ +K+R A
Sbjct: 1336 FEKSLMAQDKILKGFSDNADKLISNDHYDSKY----IGDRRNQVLGKRKAVKDR----AF 1387
Query: 819 EHQRQEENDKLRREFAKLANAFHAWLTN-TR---QEMMEAGGTLEEQLDAVERKAKEIKA 652
E +R + K +FA A+ WL + TR E L +L + +E++A
Sbjct: 1388 ERKRLLQASKDFHKFAAEADDLKVWLQDKTRIAGDENYRDLSNLPRKLQKHQAFERELRA 1447
Query: 651 NKGQLRQIEEKGAMLERNLILDNRY--TEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQAR 478
N+GQLR + + G L + NR E + + W L L+ LEQ R
Sbjct: 1448 NEGQLRNVTKDGQALVQ---AGNRVPEVESRVADLNKRWKDLLTLSEDKGRKLEQAASQR 1504
Query: 477 NQSGVSEEALRE 442
+ E+A ++
Sbjct: 1505 EHNRSLEDAKKK 1516
Score = 145 bits (366), Expect = 1e-32
Identities = 99/418 (23%), Positives = 192/418 (45%)
Frame = -1
Query: 2838 RDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNI 2659
RD++L + E L Q +K + L+ E ++ E Q+ + Y +
Sbjct: 385 RDELLRQ-----EKLEQLNYKFEKKSVLR---------EGYLKEMIQVLSDPRYLRQVDA 430
Query: 2658 QQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVK 2479
K K +A A++ A +R + L + + G+ V R + + +W L++
Sbjct: 431 TLK--KHEAISADILARVERFNDLTAMAEEL--DRENYHGKERVRRREQEVMAKWRQLLE 486
Query: 2478 TTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEA 2299
+ L + + + + + + E++ SED G L VE LL+ HSL E
Sbjct: 487 LLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQFASEDVGPHLLGVEELLQAHSLQEL 546
Query: 2298 DIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALN 2119
+ + + + N QA ++ +A+R + + Y + + + RR +L +A N
Sbjct: 547 QVNTYGETLKRFNRQALPYKSSEHKDAALLAQRLADLEEAYSELLRRSAARRARLEEARN 606
Query: 2118 VHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKL 1939
H F D D+EESW+ +K+ + + +DL V +L++KH+ ++ E+ S +P+ +
Sbjct: 607 FHHFMEDYDNEESWLVDKQRICKTGITAKDLRAVLSLQQKHKALEDEIKSRKPKSGQMST 666
Query: 1938 KGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEE 1759
G+ L+ E +I+ R++ L + W + L R ++L+++ F D E
Sbjct: 667 AGKRLI---GEQHPRSSEIQSRIDSLAEHWQALEALVELRRRQLEDAAEAYQFYTDANEA 723
Query: 1758 EAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNG 1585
E+W+NEK ++ S ++G + Q LL++H Q +L + + +L + D LI G
Sbjct: 724 ESWLNEKIALVNSRDYGNDEPSAQALLQRHRDLQGELNAYSGDILNLNQQADKLIKAG 781
Score = 137 bits (344), Expect = 5e-30
Identities = 120/502 (23%), Positives = 222/502 (43%), Gaps = 20/502 (3%)
Frame = -1
Query: 3360 DLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRT-----------EIDSRAATFQAF 3214
+L+ WI + ++L N + G + L +EYRT EI++ T
Sbjct: 287 NLLSWIRQKTLELEQRDLPNSLEGIQRELLAFKEYRTIEKPPKYKERSEIEALYFTINTL 346
Query: 3213 DQFGNQLLNSHH--YAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQ 3040
+ NQ + DIE Q + A E A R +L Q QL Y+ ++
Sbjct: 347 LKALNQPPYNPQDGQLVNDIEKAWQILEYAEHHREVA--LRDELLRQEKLEQLNYKFEKK 404
Query: 3039 ADTWMSAREAFLAQ-----EDPSG-DNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLI 2878
+ RE +L + DP V++ +KKHE I + E+ L AE L
Sbjct: 405 S----VLREGYLKEMIQVLSDPRYLRQVDATLKKHEAISADILARVERFNDLTAMAEELD 460
Query: 2877 KNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTE-KF 2701
+ N++ V R+ +++ +W L E L +R L + L R+ + E +
Sbjct: 461 RENYHGKERVRRREQEVMAKWRQLLELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQ 520
Query: 2700 QIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSA 2521
Q A E+ +++ Q E +++ + + + L + A ++
Sbjct: 521 QFASEDVGPHLLGVEELLQAHSLQELQVNTYGETLKRFNRQA--LPYKSSEHKDAALLAQ 578
Query: 2520 RLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLA 2341
RL L + + L++ + + RL+EA FM + E WL + + + ++ KDL
Sbjct: 579 RLADLEEAYSELLRRSAARRARLEEARNFHHFMEDYDNEESWLVDKQRICKTGITAKDLR 638
Query: 2340 SVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKK 2161
+V +L +KH LE +I + + + G+M+ L+ + +I R +A+ + ++
Sbjct: 639 AVLSLQQKHKALEDEIKSRKPKSGQMSTAGKRLIGEQHPRSSEIQSRIDSLAEHWQALEA 698
Query: 2160 MATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDT 1981
+ RR +L A +QF+ D ++ ESW+ EK LV+S DYG D P Q L ++HR +
Sbjct: 699 LVELRRRQLEDAAEAYQFYTDANEAESWLNEKIALVNSRDYGNDEPSAQALLQRHRDLQG 758
Query: 1980 ELASHEPQVSLVKLKGEELLRS 1915
EL ++ + + + ++L+++
Sbjct: 759 ELNAYSGDILNLNQQADKLIKA 780
Score = 95.9 bits (237), Expect = 1e-17
Identities = 92/499 (18%), Positives = 195/499 (38%), Gaps = 17/499 (3%)
Frame = -1
Query: 6753 ILYWIREKETYVTAEDMGMDLEHVEILQRKFDDF--------LKELGNHQYRINEINQAA 6598
+L WIR+K + D+ LE ++ F ++ KE + IN
Sbjct: 288 LLSWIRQKTLELEQRDLPNSLEGIQRELLAFKEYRTIEKPPKYKERSEIEALYFTINTLL 347
Query: 6597 DKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATR----KEGLFGAHQVQRFNRDADETL 6430
L + ++ D + +D+ AW L R ++ L ++++ N ++
Sbjct: 348 KALNQPPYNPQDG--QLVNDIEKAWQILEYAEHHREVALRDELLRQEKLEQLNYKFEKKS 405
Query: 6429 A----WIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAET 6262
++ E LS Y L V A +KHE D+ A + L A +L
Sbjct: 406 VLREGYLKEMIQVLSDPRY---LRQVDATLKKHEAISADILARVERFNDLTAMAEELDRE 462
Query: 6261 HPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVI 6082
+ E + ++ + A W L E ++++ L + L L + + +++
Sbjct: 463 NYHGKERVRRREQEVMAKWRQLLELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQF 522
Query: 6081 GADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEK 5902
++++ + G E LL++H + +++ ++ + ++ + ++L
Sbjct: 523 ASEDVGPHLLGVEELLQAHSLQELQVNTYGETLKRFNRQALPYKSSEHKDAALLAQRLAD 582
Query: 5901 LDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEH 5722
L+ S LL RR E+ + F D + E+W+ ++ L +V
Sbjct: 583 LEEAYSELLRRSAARRARLEEARNFHHFMEDYDNEESWLVDKQRICKTGITAKDLRAVLS 642
Query: 5721 LIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXX 5542
L +KH+ E + +++ K + +LI QH + ++
Sbjct: 643 LQQKHKALEDEIKSRKPKSGQMSTAGKRLIGEQHPRSSEIQSRIDSLAEHWQALEALVEL 702
Query: 5541 RGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSY-LDPTNIRGKLQKHINFEQELKA 5365
R L+++ + F D +E SW+ EK++ Y D + + LQ+H + + EL A
Sbjct: 703 RRRQLEDAAEAYQFYTDANEAESWLNEKIALVNSRDYGNDEPSAQALLQRHRDLQGELNA 762
Query: 5364 NENRLDDIRSTGEQIIDSG 5308
+ ++ +++I +G
Sbjct: 763 YSGDILNLNQQADKLIKAG 781
Score = 38.9 bits (89), Expect = 1.9
Identities = 57/242 (23%), Positives = 94/242 (38%), Gaps = 16/242 (6%)
Frame = -1
Query: 1092 SWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQ--------RSLSSAEEDFRQLQDLDRR 937
SW +L NSLE I+ A E++ + S E + + L
Sbjct: 290 SWIRQKTLELEQRDLPNSLEGIQRELLAFKEYRTIEKPPKYKERSEIEALYFTINTL--- 346
Query: 936 IKSFNVGP-NPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLAN 760
+K+ N P NP ++ +E W+ L+ RE L E RQE+ ++L +F K +
Sbjct: 347 LKALNQPPYNPQDGQLVNDIEKAWQILEYAEHHREVALRDELLRQEKLEQLNYKFEKKSV 406
Query: 759 AFHAWLTNTRQEMMEAGGTLEEQLDAVERKAKEIKAN-KGQLRQIEEKGAM---LERNLI 592
+L Q + + Q+DA +K + I A+ ++ + + AM L+R
Sbjct: 407 LREGYLKEMIQVLSDP--RYLRQVDATLKKHEAISADILARVERFNDLTAMAEELDRENY 464
Query: 591 LDNRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARN---QSGVSEEALREFSMMFKH 421
+ W QL +L + NL Q N + + EA+RE F
Sbjct: 465 HGKERVRRREQEVMAKWRQLLELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQFAS 524
Query: 420 FD 415
D
Sbjct: 525 ED 526
>gi|24656802|ref|NP_523900.1| CG12008-PA [Drosophila melanogaster]
gi|7292359|gb|AAF47766.1| CG12008-PA [Drosophila melanogaster]
Length = 4097
Score = 756 bits (1952), Expect = 0.0
Identities = 577/2347 (24%), Positives = 1044/2347 (43%), Gaps = 92/2347 (3%)
Frame = -1
Query: 7128 KRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENFRDPSNLQAKIQKHEA-------F 6970
K+ L + Q F R+AD+++ T E F + +NL A + + EA F
Sbjct: 1283 KQKWLLQCVDLQMFNREADKIDA------TTKSHEAFLEYNNLGASLDEVEAILKRHLDF 1336
Query: 6969 EAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQA 6790
E + A K + + +I ++H+ S++I R ++ + LQ +
Sbjct: 1337 EKSLMAQDKILKGFSDNADKLISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQAS 1396
Query: 6789 LKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEI 6610
F + D++ W+++K T + ++ DL ++ +K F +EL ++ ++ +
Sbjct: 1397 KDFHKFAAEADDLKVWLQDK-TRIAGDENYRDLSNLPRKLQKHQAFERELRANEGQLRNV 1455
Query: 6609 NQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETL 6430
+ LV+ G+ ++ + D+N W L TL+ + L A + NR ++
Sbjct: 1456 TKDGQALVQAGNRV-PEVESRVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAK 1514
Query: 6429 AWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDR 6250
+ E D AL S D G DL + + L K + E ++ + K+ +L +A
Sbjct: 1515 KKVDELDSALRSGDVGNDLRSCKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFN 1574
Query: 6249 AEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADE 6070
A+ I + + + L++ Q R+ LE S H+F+ + WI + ++E
Sbjct: 1575 AQNIEAGTKELQQRFKDLRDPTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKSNE 1634
Query: 6069 LAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHE 5890
L +++ A++L + H++ + EI N+ AGQ L+ PE +V+ ++L+
Sbjct: 1635 LGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALVAGQSLISQQHPEREQVESLCQQLEQA 1694
Query: 5889 KSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKK 5710
L ER + + Q + D + E+W+ ++ L +T+ G DS L+ K
Sbjct: 1695 WQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLLTK 1754
Query: 5709 HEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNA 5530
H+ E L + + ++ H + +A R
Sbjct: 1755 HKTIELELDTYSGIVTEMGHSCAAMVAANHPDSKVLAAKQQLIEKMLKSLHKLASQRQGR 1814
Query: 5529 LKESYKRQTFDRDCDEMVSWITEKLSTARDDSY-LDPTNIRGKLQKHINFEQELKANENR 5353
L ES + + + DE+ WI E+ A + Y D +++ K + + ++ +R
Sbjct: 1815 LMESLYKHEYFLESDEVEQWIREQEQAASSEDYGQDFEHLQLLQNKFDDLKHRVEVGADR 1874
Query: 5352 LDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNI 5173
+D +++IDS A+ + R Q+ W L+ N++ KL AG +F+R++
Sbjct: 1875 VDQCELLAKKLIDSESPYANEVEKRQEQLRTSWENLLQLLNQREQKLHAAGEIHRFHRDV 1934
Query: 5172 EDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEE 4993
+ + + + S++ G+DL S L +K E+D A ++ + + + + Q +
Sbjct: 1935 AEALFRIQD-KNAALSQELGRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSVRLQAK 1993
Query: 4992 EHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVA 4813
NA I ++Q+ + +N L++ R +L S D+ D ++W
Sbjct: 1994 YPSNASAIAQQQDKVVAAWNDLKERSTARGDRLAASSDLQTFLTDVRDIVSWSSNLRAAL 2053
Query: 4812 GSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQ 4633
+ D G L + A+ EI + + ++ ++ M+Q GH+ A ++ +K A
Sbjct: 2054 QAEEHVSDAAGATALKIQHDAIYGEIEAREDKFRYLNELSDSMVQTGHYAAADVEEKCAA 2113
Query: 4632 LRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEA 4453
+ D + L + K++ L+ + +L DA + D S ++ + S+D+G+ + +
Sbjct: 2114 MLDERQKLHAAWNKKKIMLEQKIDLFCFLRDAKQIDNLSSSQQAALSSSDFGQTVEDVQN 2173
Query: 4452 LLKKH----RALLSDLEAFKGTIEDLRKQASQCKYQEQPM-------------------- 4345
++KH R + + E E RK Q Y +
Sbjct: 2174 KIRKHDEFERLIQTQEEKVSLLQEHGRKLIEQRHYDSANIQTILQGVLARRQKVKDLCAV 2233
Query: 4344 -----------GQLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQ 4198
+ RDC A Y EK + + D + +N D ++ Q
Sbjct: 2234 RRYKLEDALLYAKFVRDCAEAKYWINEKQKK----LEADAASYAEVTNLDEKIKKLQKHQ 2289
Query: 4197 GFVPAAYVKRIEPGTAQQHAQQQVNSIG----GKQSE-----------IEDKYQRLMMLG 4063
F A Q Q++ G KQ E + + +Q L+
Sbjct: 2290 AFQAEV--------AANQGRIQEIQDTGVILLSKQHESSPEIKRAIEIVLEAWQGLLAEL 2341
Query: 4062 ETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDL 3883
E R R LEEA + + + + WI+ +E + + G DLE L +K DD D+
Sbjct: 2342 EQRGRGLEEAQDSLEFNSQLDKIEAWIRDKEMMVQASDTGRDLEHCNALMRKLDDVDSDM 2401
Query: 3882 KANEVRLQEMNQIATALTSVGQTETAVR-IRQQIEDLNARWRALXXXXXXXXXQLGSAHE 3706
+ ++ R++ +NQ+A L + Q + + ++ +D N WR L LG A+E
Sbjct: 2402 RVDDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYNWRQLQGALNAYRALLGGANE 2461
Query: 3705 VQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDE 3526
+ F+RDVD+T D I EK A+ S D GRDL +V+AL R+ E +ERD++A+ KI +
Sbjct: 2462 IHVFNRDVDDTADRIAEKSLAMSSTDTGRDLAAVEALIRREEALERDMSAVKQKIDQHET 2521
Query: 3525 KANRLRQSHPE-AAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQ 3349
A L + +PE A+ I EL++ W L + + R+ L ++Y +F+SD ++L
Sbjct: 2522 AAEFLIKKYPERGAQHIERKLEELHKSWGNLQALSVKRQSILNEAYLAHKFVSDVKELEL 2581
Query: 3348 WIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAA 3169
W+ M + +++ + + + E LE HQE + EI+ R F Q G QL
Sbjct: 2582 WVNDMIKKMNNTQSPSTINDCETQLELHQERKVEIEGRQEAFAGLKQQGEQLSKRPQQQQ 2641
Query: 3168 GD-IENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQED 2992
D + L + E + L +AW R L + +LQLF EQ + W++ +EAFL +D
Sbjct: 2642 PDNVRKYLLVLEELHQTLNEAWSERARDLTEAHQLQLFKAQVEQVEIWLANKEAFLNNDD 2701
Query: 2991 PSGDN---VESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILD 2821
GD+ VE L+KKH++F+K ++ + + L+ FA S+++ D+ + K IL
Sbjct: 2702 -LGDSYTAVERLLKKHDEFEKLLHA--DHVDTLQKFANSILEGEPKDADLIREKLAYILR 2758
Query: 2820 RWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNIQQKHQK 2641
R L E +++ +L +S LQ+F R EI+ W+ +K Q+A +ENYR+P+N+Q K QK
Sbjct: 2759 RKQKLLELSEERKQRLTQSHQLQEFLRSLYEIDRWLVQKLQVALDENYREPSNLQSKIQK 2818
Query: 2640 QQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKS 2461
AF+AEL +NS R+ ++I G LI E A +L L W L + K
Sbjct: 2819 HAAFDAELLSNSPRVQSVIHEGERLIRGDHFAKDEIAQQVQL--LEGDWLKLKGASQTKK 2876
Query: 2460 YRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQ 2281
+L++A +F +V + W+ EVE+ L SEDYGKDLA+V NLLKKH LEAD+ H
Sbjct: 2877 DKLQQAYDALAFNRSVDEFNNWMDEVELQLSSEDYGKDLAAVSNLLKKHERLEADVAHHG 2936
Query: 2280 DRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFR 2101
+ ++ ++ + + + F +I ER + RY+ + + RR+ L +L++ QF R
Sbjct: 2937 ELADQLKQKDEQFFQAEHFLRHEIHERATVSIRRYNTLHEPLGIRRENLEDSLSLQQFLR 2996
Query: 2100 DIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELL 1921
D +DE W+ EK+L+ S D G L VQ L++KH ++ EL S EP + + +G++++
Sbjct: 2997 DAEDELQWLAEKQLVAGSQDLGTSLLSVQGLQKKHNSLEAELTSQEPLIQALLQRGQQMI 3056
Query: 1920 RSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNE 1741
R + +Q++ + E L++ Q+RDL R RL ++ Q F + E +AWM E
Sbjct: 3057 R---DNHFASEQLQYKSELLQKQLVQLRDLAAIRRLRLLDAVESQLFYVEANEADAWMRE 3113
Query: 1740 KQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIK 1561
K+ +L S ++G + VQG KK + Q +L K + + LI + + +I
Sbjct: 3114 KRPVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPSIEKVAKLATGLIERNHFDSSNIA 3173
Query: 1560 QRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDL 1381
++ Q+ ++ +A+ R ++L + +++ + + + W+ ++ SED+G D+
Sbjct: 3174 EKNAQVGQEYEDLLRLAKERESRLGECKKLFEYLRETEELHEWVGDQMAVTASEDYGEDV 3233
Query: 1380 SSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNL 1201
V+ L+ E+F + LNA E ++ E D+L+ + +I+ + Q W+ L
Sbjct: 3234 EHVEQLILAFESFVSNLNANEAR-VEACLERGDRLIQENNPYRSSIKSKRDETKQLWEEL 3292
Query: 1200 L----AHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLE 1033
A +A E + L K AS + E+ +D LE
Sbjct: 3293 KDLVHARQDALAGAKQVHVYDRVADETIQLINEKDASLIS---EDYGQD---------LE 3340
Query: 1032 EIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQR 853
I+AL H F+ L + + ++ + D + W +L+
Sbjct: 3341 SIQALGRKHQVFESELVGIQGQVDSVLAEAAKLGEIYPDAKEHIEVKRDETVEAWTDLKE 3400
Query: 852 IIKEREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEMMEAGGTLEEQLDAVER 673
R+ +L++ Q Q D+ R A + N A +T AG L L + +
Sbjct: 3401 KTAARKNKLSQAEQLQSYFDEYRDLIAWI-NEMLAKITAPELANSVAGAEL--LLASTKD 3457
Query: 672 KAKEIKANKGQLRQIEEKGAMLERNLILDNRYTEHST---VGIAQAWDQL---------- 532
EI+ + G + LI + + H + + QA +L
Sbjct: 3458 HDTEIRTRDETFAKFAANG----QQLIKEKHFLAHEVEDKIKVLQARHELLKHTLNKRRE 3513
Query: 531 -------DQLAMRMQHNLEQQIQAR----NQSGVSEEALREFSMMFKHFDKEKTGRLDHQ 385
QL ++ LEQ I +R + + + + ++ +H D EKT +
Sbjct: 3514 IYELNLDTQLFLKDAEILEQWISSREPQLKDTKLGDSIPQVEDLLRRHEDFEKTVAAQEE 3573
Query: 384 QFKSCLR 364
+F++ R
Sbjct: 3574 KFQAIKR 3580
Score = 755 bits (1949), Expect = 0.0
Identities = 547/2178 (25%), Positives = 1007/2178 (46%), Gaps = 67/2178 (3%)
Frame = -1
Query: 6924 KTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILY 6745
+T I N ++ ++KR + ++ + + L+ ++ L F R+CD+
Sbjct: 936 RTSTQSINEN---ADSVEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEK 992
Query: 6744 WIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEH 6565
W++EKE + +++ E V+ +RKF+ F+ +L R+ EI+ A D +GHS+
Sbjct: 993 WMKEKERMIKSDEG----EGVDNAKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQL 1048
Query: 6564 DQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDY 6385
D+I ++ ++ W RLN A R++ L GA V+ FNR DE W+ EK L L +
Sbjct: 1049 DKIIARQRQIHQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVI 1108
Query: 6384 GRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAW 6205
DL VQALQR+H+ ER+LA +E K+ ++ + + +P + ++ + + + W
Sbjct: 1109 TPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQDMW 1168
Query: 6204 NALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESH 6025
++++ ++ +E F + L++WI +K + ADE A+DV A LL+ H
Sbjct: 1169 QQVQQRGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKH 1228
Query: 6024 QEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILY 5845
+ +I A F + G++L + G P E +E+L E+ ++ W E++
Sbjct: 1229 NDLGDDIRAHDTEFVEVIQLGKQLSD-GKPNMAETVAVIERLKAEQDAIHRGWAEKQKWL 1287
Query: 5844 EQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKI 5665
QC+DLQ+F R+ ++ + EAFL +LG SLD VE ++K+H DFEKSL AQ++ +
Sbjct: 1288 LQCVDLQMFNREADKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLDFEKSLMAQDKIL 1347
Query: 5664 NALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCD 5485
+ A KLI HY + + + R L+ S F + D
Sbjct: 1348 KGFSDNADKLISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEAD 1407
Query: 5484 EMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGH 5305
++ W+ +K A D++Y D +N+ KLQKH FE+EL+ANE +L ++ G+ ++ +G+
Sbjct: 1408 DLKVWLQDKTRIAGDENYRDLSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQAGN 1467
Query: 5304 FAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVAS 5125
+ + R+ +N W +L+ + KG KL +A ++++ NR++ED + + EL+ + S
Sbjct: 1468 RVPE-VESRVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDSALRS 1526
Query: 5124 EDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQ 4945
D G DL S ++L K ++ES+ + +V + HFNA I + LQ
Sbjct: 1527 GDVGNDLRSCKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQ 1586
Query: 4944 QRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLI 4765
QR+ LRDP ++R+ KL ES ++ +++ E WI E A S G++L Q+L
Sbjct: 1587 QRFKDLRDPTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKSNELGQNLHQAQSLH 1646
Query: 4764 KKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRR 4585
KK + L AEI H I A +I Q H ++ QL W+ L+ +R
Sbjct: 1647 KKHKKLEAEIKGHQPMINKALVAGQSLISQQHPEREQVESLCQQLEQAWQDLERHCGERS 1706
Query: 4584 TDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFK 4405
LD SL+A QYL DA E ++W+ E+ ++ ST+YG+D DSA LL KH+ + +L+ +
Sbjct: 1707 RKLDMSLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLLTKHKTIELELDTYS 1766
Query: 4404 GTIEDLRKQASQCKYQEQPMGQLGRDCVLALYDYQEKSPREVSMKKGDVLT-------LL 4246
G + ++ + P ++ + + + S ++G ++ L
Sbjct: 1767 GIVTEMGHSCAAMVAANHPDSKVLAAKQQLIEKMLKSLHKLASQRQGRLMESLYKHEYFL 1826
Query: 4245 NASNRDWWKVEVNDR-------QGFVPAAYVK--------RIEPGT-----AQQHAQQQV 4126
+ + W E Q F ++ R+E G + A++ +
Sbjct: 1827 ESDEVEQWIREQEQAASSEDYGQDFEHLQLLQNKFDDLKHRVEVGADRVDQCELLAKKLI 1886
Query: 4125 NS-------IGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREA 3967
+S + +Q ++ ++ L+ L R++KL A + ++ R+ + I+ + A
Sbjct: 1887 DSESPYANEVEKRQEQLRTSWENLLQLLNQREQKLHAAGEIHRFHRDVAEALFRIQDKNA 1946
Query: 3966 VAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQ 3787
A QE+G DL L +K + F+ DL A E +LQ + + + L A I QQ
Sbjct: 1947 -ALSQELGRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSVRL-QAKYPSNASAIAQQ 2004
Query: 3786 IEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRS 3607
+ + A W L +L ++ ++Q F DV + W AL +E+ D
Sbjct: 2005 QDKVVAAWNDLKERSTARGDRLAASSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAG 2064
Query: 3606 VQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSK 3427
AL+ +H+ + ++ A DK + L+E ++ + Q+ AA + + + ++ +L +
Sbjct: 2065 ATALKIQHDAIYGEIEAREDKFRYLNELSDSMVQTGHYAAADVEEKCAAMLDERQKLHAA 2124
Query: 3426 ANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTE 3247
N +K L D FL D + + +S +SS + V + + +H E+
Sbjct: 2125 WNKKKIMLEQKIDLFCFLRDAKQIDNLSSSQQAALSSSDFGQTVEDVQNKIRKHDEFERL 2184
Query: 3246 IDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLEL 3067
I ++ + G +L+ HY + +I+ LQGV R+ ++D RR L+ L
Sbjct: 2185 IQTQEEKVSLLQEHGRKLIEQRHYDSANIQTILQGVLARRQKVKDLCAVRRYKLEDALLY 2244
Query: 3066 QLFYRDCEQADTWMSAREAFLAQEDPSGDNVESL------IKKHEDFDKAINTQEEKIKG 2905
F RDC +A W++ ++ L + S V +L ++KH+ F + + +I+
Sbjct: 2245 AKFVRDCAEAKYWINEKQKKLEADAASYAEVTNLDEKIKKLQKHQAFQAEVAANQGRIQE 2304
Query: 2904 LKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEI 2725
++ L+ H SP + R + +L+ W GL L Q+ L E+Q +F+ D+I
Sbjct: 2305 IQDTGVILLSKQHESSPEIKRAIEIVLEAWQGLLAELEQRGRGLEEAQDSLEFNSQLDKI 2364
Query: 2724 ENWMTEKFQIAQ-EENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKC 2548
E W+ +K + Q + RD + +K ++++ + R+ I Q + LI A+
Sbjct: 2365 EAWIRDKEMMVQASDTGRDLEHCNALMRKLDDVDSDMRVDDQRVKHINQLADKLINQAQV 2424
Query: 2547 GGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQ 2368
+V R K N W L L AN+ F V D + E + +
Sbjct: 2425 PADTQSVDKRRKDFNYNWRQLQGALNAYRALLGGANEIHVFNRDVDDTADRIAEKSLAMS 2484
Query: 2367 SEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERR-KL 2191
S D G+DLA+VE L+++ LE D+ A + ++ + A+ L++ +G Q ER+ +
Sbjct: 2485 STDTGRDLAAVEALIRREEALERDMSAVKQKIDQHETAAEFLIKKYPERGAQHIERKLEE 2544
Query: 2190 IADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQN 2011
+ + ++ ++ R+ L++A H+F D+ + E W+ + +++ + +
Sbjct: 2545 LHKSWGNLQALSVKRQSILNEAYLAHKFVSDVKELELWVNDMIKKMNNTQSPSTINDCET 2604
Query: 2010 LRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDL 1831
H+ E+ + + +K +GE+L + + D ++K + LE+ + +
Sbjct: 2605 QLELHQERKVEIEGRQEAFAGLKQQGEQLSKRPQQQ--QPDNVRKYLLVLEELHQTLNEA 2662
Query: 1830 TGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVD 1651
R + L E+ Q F VE+ E W+ K+ L +D+ G++ V+ LLKKHD F +
Sbjct: 2663 WSERARDLTEAHQLQLFKAQVEQVEIWLANKEAFLNNDDLGDSYTAVERLLKKHDEF--E 2720
Query: 1650 LELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAY 1471
LH V L ++++ A I+++ + R ++ ++E R +L +
Sbjct: 2721 KLLHADHVDTLQKFANSILEGEPKDADLIREKLAYILRRKQKLLELSEERKQRLTQSHQL 2780
Query: 1470 LQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITE 1291
+F+ ++ W+ +K Q E++ R+ S++Q + K AFDA L + +Q +
Sbjct: 2781 QEFLRSLYEIDRWLVQKLQVALDENY-REPSNLQSKIQKHAAFDAELLS-NSPRVQSVIH 2838
Query: 1290 LKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELY--LAF 1117
++L+ +H I ++ + W L S+ ++ ++++ Y LAF
Sbjct: 2839 EGERLIRGDHFAKDEIAQQVQLLEGDWLKLKGASQTKK----------DKLQQAYDALAF 2888
Query: 1116 AKKASTFNSWFENAEEDLT------DPVRCNSL----EEIRALRDAHGEFQRSLSSAEED 967
+ FN+W + E L+ D ++L E + A HGE L +E
Sbjct: 2889 NRSVDEFNNWMDEVELQLSSEDYGKDLAAVSNLLKKHERLEADVAHHGELADQLKQKDEQ 2948
Query: 966 FRQLQDLDRR---------IKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQEL--AR 820
F Q + R I+ +N P + LED+ +LQ+ +++ E EL
Sbjct: 2949 FFQAEHFLRHEIHERATVSIRRYNTLHEP-LGIRRENLEDS-LSLQQFLRDAEDELQWLA 3006
Query: 819 EHQRQEENDKLRREFAKLANAFHAWLTNTRQEMMEAGGTLEEQL--DAVERKAKEIKANK 646
E Q + L + + +EA T +E L ++R + I+ N
Sbjct: 3007 EKQLVAGSQDLGTSLLSVQG------LQKKHNSLEAELTSQEPLIQALLQRGQQMIRDNH 3060
Query: 645 GQLRQIEEKGAMLERNLI 592
Q++ K +L++ L+
Sbjct: 3061 FASEQLQYKSELLQKQLV 3078
Score = 637 bits (1643), Expect = e-180
Identities = 404/1525 (26%), Positives = 749/1525 (48%), Gaps = 100/1525 (6%)
Frame = -1
Query: 5472 WITEKLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAAD 5293
++ E + D YL + L+KH ++ A R +D+ + E++ + +
Sbjct: 411 YLKEMIQVLSDPRYL--RQVDATLKKHEAISADILARVERFNDLTAMAEELDRENYHGKE 468
Query: 5292 HIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYG 5113
+ R ++V W +L++ + L + N R I + EL+ Q ASED G
Sbjct: 469 RVRRREQEVMAKWRQLLELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQFASEDVG 528
Query: 5112 KDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYN 4933
L+ V+ L + L E N + + + + A ++ EH +A ++ ++ +L++ Y+
Sbjct: 529 PHLLGVEELLQAHSLQELQVNTYGETLKRFNRQALPYKSSEHKDAALLAQRLADLEEAYS 588
Query: 4932 ALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQ 4753
L R+ +L E+ + D ++E +W+ +K+++ + +DL V +L +K +
Sbjct: 589 ELLRRSAARRARLEEARNFHHFMEDYDNEESWLVDKQRICKTGITAKDLRAVLSLQQKHK 648
Query: 4752 ALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLD 4573
AL EI + + +S+A +I + H + EI+ ++ L ++W+ L++ E RR L+
Sbjct: 649 ALEDEIKSRKPKSGQMSTAGKRLIGEQHPRSSEIQSRIDSLAEHWQALEALVELRRRQLE 708
Query: 4572 DSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIE 4393
D+ +A+Q+ +DANEA++W++EK +V S DYG DE SA+ALL++HR L +L A+ G I
Sbjct: 709 DAAEAYQFYTDANEAESWLNEKIALVNSRDYGNDEPSAQALLQRHRDLQGELNAYSGDIL 768
Query: 4392 DLRKQ------ASQCKYQ----EQPMGQLGRD---------------------------- 4327
+L +Q A C + E + ++ ++
Sbjct: 769 NLNQQADKLIKAGICTLELSAAEPELPEVEQEEWVNETRLVPKEVWEDEWVEKLEHKKVT 828
Query: 4326 ------CVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEV-NDRQGFVPAAYVKR 4168
V +L+ ++ + + M KG+V+ L + +N DWW V N +GFVPA YV+
Sbjct: 829 ETKMLPHVKSLFPFEGQG---MKMDKGEVMLLKSKTNDDWWCVRKDNGVEGFVPANYVRE 885
Query: 4167 IEPG-----------------------------------------------TAQQHAQQQ 4129
+EP T+ Q +
Sbjct: 886 VEPRPVACIVPKAEKVKSLQKVKKTILVRQVVPVKRIKPVSVAPKPLVQRRTSTQSINEN 945
Query: 4128 VNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQE 3949
+S+ +Q I Y L + + R LE++ + RE +D +W+K +E + E
Sbjct: 946 ADSVEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKERMIKSDE 1005
Query: 3948 IGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNA 3769
E V+ ++KF+ F DL A R++E++ G ++ I +Q ++
Sbjct: 1006 G----EGVDNAKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDKIIARQ-RQIHQ 1060
Query: 3768 RWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQR 3589
W+ L L A V+ F+R DE + W+ EK LD+ DLR+VQALQR
Sbjct: 1061 IWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVITPDLRTVQALQR 1120
Query: 3588 KHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKE 3409
+H+ +ER+LA + DK+ + N ++ ++P + + Q+E+ + W ++ + ++ +
Sbjct: 1121 RHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQDMWQQVQQRGSDLRN 1180
Query: 3408 KLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAA 3229
++ Q F + + L+ WI S+ +++ E A DV A LL++H + +I +
Sbjct: 1181 RIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDLGDDIRAHDT 1240
Query: 3228 TFQAFDQFGNQLLNSHHYAAGDIE--NRLQGVNEARKGLEDAWVARRNILDQCLELQLFY 3055
F Q G QL + A + RL+ +A + W ++ L QC++LQ+F
Sbjct: 1241 EFVEVIQLGKQLSDGKPNMAETVAVIERLKAEQDA---IHRGWAEKQKWLLQCVDLQMFN 1297
Query: 3054 RDCEQADTWMSAREAFLAQED--PSGDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESL 2881
R+ ++ D + EAFL + S D VE+++K+H DF+K++ Q++ +KG A+ L
Sbjct: 1298 READKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLDFEKSLMAQDKILKGFSDNADKL 1357
Query: 2880 IKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKF 2701
I N+HYDS + +R+Q+L + +K+ +++ L S+ +F+ +AD+++ W+ +K
Sbjct: 1358 ISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKT 1417
Query: 2700 QIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSA 2521
+IA +ENYRD +N+ +K QK QAFE EL AN ++ + + G L++ G V +
Sbjct: 1418 RIAGDENYRDLSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQ---AGNRVPEVES 1474
Query: 2520 RLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLA 2341
R+ LN +W L+ + +K +L++A Q+ +++D + + E++ L+S D G DL
Sbjct: 1475 RVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDSALRSGDVGNDLR 1534
Query: 2340 SVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKK 2161
S ++L+ K +LE++I +V E+ D + F Q I K + R+ ++
Sbjct: 1535 SCKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQQRFKDLRD 1594
Query: 2160 MATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDT 1981
RR KL ++LN H+F ++D E WI E S++ G++L Q+L +KH++++
Sbjct: 1595 PTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKSNELGQNLHQAQSLHKKHKKLEA 1654
Query: 1980 ELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDE 1801
E+ H+P ++ + G+ L+ ++ +Q++ + LEQ+W + G R ++LD
Sbjct: 1655 EIKGHQPMINKALVAGQSLI---SQQHPEREQVESLCQQLEQAWQDLERHCGERSRKLDM 1711
Query: 1800 SEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVAD 1621
S Q +L D E E+W+ E+ +L S +G + LL KH T +++L+ + V +
Sbjct: 1712 SLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLLTKHKTIELELDTYSGIVTE 1771
Query: 1620 LINKGDTLIHNGNHHAPHIKQRCDQLRARLIE-IESMAEGRLAKLRDNSAYLQFMWKCDV 1444
+ + ++ NH + QL ++++ + +A R +L ++ ++ + D
Sbjct: 1772 MGHSCAAMV-AANHPDSKVLAAKQQLIEKMLKSLHKLASQRQGRLMESLYKHEYFLESDE 1830
Query: 1443 VESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITE---LKDQLV 1273
VE WI E+EQ SED+G+D +Q+L Q FD L G R+ + L +L+
Sbjct: 1831 VEQWIREQEQAASSEDYGQDFEHLQLL---QNKFD-DLKHRVEVGADRVDQCELLAKKLI 1886
Query: 1272 SSEHQQSPAIEKRHTNVIQRWQNLL 1198
SE + +EKR + W+NLL
Sbjct: 1887 DSESPYANEVEKRQEQLRTSWENLL 1911
Score = 610 bits (1573), Expect = e-172
Identities = 410/1364 (30%), Positives = 666/1364 (48%), Gaps = 44/1364 (3%)
Frame = -1
Query: 7176 QEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEE--NFRDPSN 7003
Q VL KD +R +LE+A + F RD E WI EK + + + ++ + +N
Sbjct: 2218 QGVLARRQKVKDLCAVRRYKLEDALLYAKFVRDCAEAKYWINEKQKKLEADAASYAEVTN 2277
Query: 7002 LQAKI---QKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXX 6832
L KI QKH+AF+AEV A+ I + TG ++ H +S IK+ +E + W
Sbjct: 2278 LDEKIKKLQKHQAFQAEVAANQGRIQEIQDTGVILLSKQHESSPEIKRAIEIVLEAWQGL 2337
Query: 6831 XXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDF 6652
+G L++A L F Q D+I WIR+KE V A D G DLEH L RK DD
Sbjct: 2338 LAELEQRGRGLEEAQDSLEFNSQLDKIEAWIRDKEMMVQASDTGRDLEHCNALMRKLDDV 2397
Query: 6651 LKELGNHQYRINEINQAADKLVEEGHSEHD--QIYKKRDDVNDAWHRLNTLAATRKEGLF 6478
++ R+ INQ ADKL+ + D + K+R D N W +L + L
Sbjct: 2398 DSDMRVDDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYNWRQLQGALNAYRALLG 2457
Query: 6477 GAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKML 6298
GA+++ FNRD D+T I EK LA+SS D GRDL V+AL R+ E ERD++A++ K+
Sbjct: 2458 GANEIHVFNRDVDDTADRIAEKSLAMSSTDTGRDLAAVEALIRREEALERDMSAVKQKID 2517
Query: 6297 QLEKEAHKLAETHPDR-AEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYR 6121
Q E A L + +P+R A+ I +K ++ +W L+ + R+ L ++ H+F++D +
Sbjct: 2518 QHETAAEFLIKKYPERGAQHIERKLEELHKSWGNLQALSVKRQSILNEAYLAHKFVSDVK 2577
Query: 6120 DLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMG 5941
+L W+ DM + + + E LE HQE K EI+ R ++F G++L +
Sbjct: 2578 ELELWVNDMIKKMNNTQSPSTINDCETQLELHQERKVEIEGRQEAFAGLKQQGEQLSKRP 2637
Query: 5940 IPESPE-VQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFL 5764
+ P+ V++ L L+ +L W ER + LQLF EQ E W+ +EAFL
Sbjct: 2638 QQQQPDNVRKYLLVLEELHQTLNEAWSERARDLTEAHQLQLFKAQVEQVEIWLANKEAFL 2697
Query: 5763 ANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXX 5584
N DLGDS +VE L+KKH++FEK L A + ++ L +FA +++G+ AD + E
Sbjct: 2698 NNDDLGDSYTAVERLLKKHDEFEKLLHA--DHVDTLQKFANSILEGEPKDADLIREKLAY 2755
Query: 5583 XXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGK 5404
R L +S++ Q F R E+ W+ +KL A D++Y +P+N++ K
Sbjct: 2756 ILRRKQKLLELSEERKQRLTQSHQLQEFLRSLYEIDRWLVQKLQVALDENYREPSNLQSK 2815
Query: 5403 LQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKK 5224
+QKH F+ EL +N R+ + GE++I HFA D I +++ + W +L A+ K
Sbjct: 2816 IQKHAAFDAELLSNSPRVQSVIHEGERLIRGDHFAKDEIAQQVQLLEGDWLKLKGASQTK 2875
Query: 5223 GAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAH 5044
KL++A + FNR++++ W+ E+E Q++SEDYGKDL +V NL KK +E+D H
Sbjct: 2876 KDKLQQAYDALAFNRSVDEFNNWMDEVELQLSSEDYGKDLAAVSNLLKKHERLEADVAHH 2935
Query: 5043 NDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLF 4864
+ D +KQ +QF + EHF I + +RYN L +PL R+ L +S Q
Sbjct: 2936 GELADQLKQKDEQFFQAEHFLRHEIHERATVSIRRYNTLHEPLGIRRENLEDSLSLQQFL 2995
Query: 4863 RDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDM 4684
RD EDEL W+ EK+ VAGS + G L+ VQ L KK +L AE+ + + I+++ M
Sbjct: 2996 RDAEDELQWLAEKQLVAGSQDLGTSLLSVQGLQKKHNSLEAELTSQEPLIQALLQRGQQM 3055
Query: 4683 IQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKE 4504
I+ HF + +++ K L+ L+ A RR L D++++ + +ANEADAWM EK
Sbjct: 3056 IRDNHFASEQLQYKSELLQKQLVQLRDLAAIRRLRLLDAVESQLFYVEANEADAWMREKR 3115
Query: 4503 PIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQAS--------QCKYQEQP 4348
P++ S+DYG+DE S + KK L +L AFK +IE + K A+ +
Sbjct: 3116 PVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPSIEKVAKLATGLIERNHFDSSNIAEK 3175
Query: 4347 MGQLGRDCVLALYDYQEKSPREVSMKK---------------GDVLTLLNASNRDWWKVE 4213
Q+G++ L +E+ R KK GD + + AS VE
Sbjct: 3176 NAQVGQEYEDLLRLAKERESRLGECKKLFEYLRETEELHEWVGDQMA-VTASEDYGEDVE 3234
Query: 4212 VNDRQGFVPAAYVKRIEPGTAQ------------QHAQQQVNSIGGKQSEIEDKYQRLMM 4069
++ ++V + A+ Q +SI K+ E + ++ L
Sbjct: 3235 HVEQLILAFESFVSNLNANEARVEACLERGDRLIQENNPYRSSIKSKRDETKQLWEELKD 3294
Query: 4068 LGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKG 3889
L R+ L A + + R A++ + I ++A ++ G DLE ++ L +K F+
Sbjct: 3295 LVHARQDALAGAKQVHVYDRVADETIQLINEKDASLISEDYGQDLESIQALGRKHQVFES 3354
Query: 3888 DLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAH 3709
+L + ++ + A L + + I + ++ W L +L A
Sbjct: 3355 ELVGIQGQVDSVLAEAAKLGEI-YPDAKEHIEVKRDETVEAWTDLKEKTAARKNKLSQAE 3413
Query: 3708 EVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLD 3529
++Q + + + WI E + + + + + L + + ++ +
Sbjct: 3414 QLQSYFDEYRDLIAWINEMLAKITAPELANSVAGAELLLASTKDHDTEIRTRDETFAKFA 3473
Query: 3528 EKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQ 3349
+L + A ++ D + L + L N R+E + D Q FL D L Q
Sbjct: 3474 ANGQQLIKEKHFLAHEVEDKIKVLQARHELLKHTLNKRREIYELNLDTQLFLKDAEILEQ 3533
Query: 3348 WIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQA 3217
WI+S + +L + + E LL RH+++ + ++ FQA
Sbjct: 3534 WISSREPQLKDTKLGDSIPQVEDLLRRHEDFEKTVAAQEEKFQA 3577
Score = 544 bits (1401), Expect = e-152
Identities = 479/2308 (20%), Positives = 974/2308 (41%), Gaps = 62/2308 (2%)
Frame = -1
Query: 7191 IHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENFRD 7012
I RR +VLG KD + ++ L+ ++ F F +AD+L VW+ +K + A +EN+RD
Sbjct: 1368 IGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKTRIAGDENYRD 1427
Query: 7011 PSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXX 6832
SNL K+QKH+AFE E++A+ + N+ K G A++Q + E ++ R+ +L+ W
Sbjct: 1428 LSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQAGNRVPE-VESRVADLNKRWKDL 1486
Query: 6831 XXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDF 6652
KG KL+QA R ++ + E ++ + + D+G DL + L K
Sbjct: 1487 LTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDSALRSGDVGNDLRSCKDLINKQQIL 1546
Query: 6651 LKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGA 6472
E+ ++ E+ D + GH I ++ + L R+ L +
Sbjct: 1547 ESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQQRFKDLRDPTQRRRAKLEES 1606
Query: 6471 HQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQL 6292
+F + D WI E A S++ G++L+ Q+L +KH+ E A ++G +
Sbjct: 1607 LNYHKFVFELDSEFQWINEHLPAAKSNELGQNLHQAQSLHKKHKKLE---AEIKGHQPMI 1663
Query: 6291 EKEA----HKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADY 6124
K +++ HP+R E + + AW L+ R L+ S + ++L D
Sbjct: 1664 NKALVAGQSLISQQHPER-EQVESLCQQLEQAWQDLERHCGERSRKLDMSLKAQQYLFDA 1722
Query: 6123 RDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEM 5944
++ SW+G+ V+ + E +D A LL H+ + E+D + + + +V
Sbjct: 1723 GEIESWLGERNNVLRSTEYGRDRDSAAKLLTKHKTIELELDTYSGIVTEMGHSCAAMVAA 1782
Query: 5943 GIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFL 5764
P+S + K + ++ SL L +R+ + + ++ ++++ E W+ +QE
Sbjct: 1783 NHPDSKVLAAKQQLIEKMLKSLHKLASQRQGRLMESLYKHEYFLESDEVEQWIREQEQAA 1842
Query: 5763 ANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXX 5584
++ D G + ++ L K +D + + ++++ + A KLI + A++V +
Sbjct: 1843 SSEDYGQDFEHLQLLQNKFDDLKHRVEVGADRVDQCELLAKKLIDSESPYANEVEKRQEQ 1902
Query: 5583 XXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGK 5404
R L + + F RD E + I +K + + D +
Sbjct: 1903 LRTSWENLLQLLNQREQKLHAAGEIHRFHRDVAEALFRIQDKNAALSQELGRDLNSALAL 1962
Query: 5403 LQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKK 5224
L+KH FE +L A E +L + ++ A I + +V WN+L + + +
Sbjct: 1963 LRKHEGFENDLVALEAQLQVLVEDSVRLQAKYPSNASAIAQQQDKVVAAWNDLKERSTAR 2022
Query: 5223 GAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAH 5044
G +L + + Q F ++ D+ +W S L + +E++ D L+ + I + A
Sbjct: 2023 GDRLAASSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEAR 2082
Query: 5043 NDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLF 4864
D+ + +L+ + H+ A + K + L K+K L +
Sbjct: 2083 EDKFRYLNELSDSMVQTGHYAAADVEEKCAAMLDERQKLHAAWNKKKIMLEQKIDLFCFL 2142
Query: 4863 RDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDM 4684
RD + ++ S++ G+ + VQN I+K I + ++ + +
Sbjct: 2143 RDAKQIDNLSSSQQAALSSSDFGQTVEDVQNKIRKHDEFERLIQTQEEKVSLLQEHGRKL 2202
Query: 4683 IQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKE 4504
I+Q H+ + I+ L + + +K RR L+D+L +++ D EA W++EK+
Sbjct: 2203 IEQRHYDSANIQTILQGVLARRQKVKDLCAVRRYKLEDALLYAKFVRDCAEAKYWINEKQ 2262
Query: 4503 PIV--GSTDYGKDEDSAEAL--LKKHRALLSDLEAFKGTIEDLRKQ-ASQCKYQEQPMGQ 4339
+ + Y + + E + L+KH+A +++ A +G I++++ Q + +
Sbjct: 2263 KKLEADAASYAEVTNLDEKIKKLQKHQAFQAEVAANQGRIQEIQDTGVILLSKQHESSPE 2322
Query: 4338 LGRDCVLALYDYQ----EKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPA---- 4183
+ R + L +Q E R +++ N S D + + D++ V A
Sbjct: 2323 IKRAIEIVLEAWQGLLAELEQRGRGLEEAQDSLEFN-SQLDKIEAWIRDKEMMVQASDTG 2381
Query: 4182 -------AYVKRIEPGTAQQHAQQQ----VNSIGGKQSEIEDKYQRLMMLGETRK----- 4051
A +++++ + Q +N + K + + RK
Sbjct: 2382 RDLEHCNALMRKLDDVDSDMRVDDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYN 2441
Query: 4050 -RKLEEACKGYQLL-----------REANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKK 3907
R+L+ A Y+ L R+ +D A+ I + + + G DL VE L ++
Sbjct: 2442 WRQLQGALNAYRALLGGANEIHVFNRDVDDTADRIAEKSLAMSSTDTGRDLAAVEALIRR 2501
Query: 3906 FDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXX 3727
+ + D+ A + ++ + A L A I +++E+L+ W L
Sbjct: 2502 EEALERDMSAVKQKIDQHETAAEFLIKKYPERGAQHIERKLEELHKSWGNLQALSVKRQS 2561
Query: 3726 QLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGD 3547
L A+ +F DV E W+ + +++ + + H+ + ++ +
Sbjct: 2562 ILNEAYLAHKFVSDVKELELWVNDMIKKMNNTQSPSTINDCETQLELHQERKVEIEGRQE 2621
Query: 3546 KIKSLDEKANRL----RQSHPEAAEQ----IYDLQRELNEQWNRLTSKANNRKEKLLDSY 3391
L ++ +L +Q P+ + + +L + LNE W + R L +++
Sbjct: 2622 AFAGLKQQGEQLSKRPQQQQPDNVRKYLLVLEELHQTLNEAW-------SERARDLTEAH 2674
Query: 3390 DYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFD 3211
Q F + + W+A+ +++ +L + T E LL++H E+ + A
Sbjct: 2675 QLQLFKAQVEQVEIWLANKEAFLNNDDLGDSYTAVERLLKKHDEFEKLL--HADHVDTLQ 2732
Query: 3210 QFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADT 3031
+F N +L A I +L + ++ L + R+ L Q +LQ F R + D
Sbjct: 2733 KFANSILEGEPKDADLIREKLAYILRRKQKLLELSEERKQRLTQSHQLQEFLRSLYEIDR 2792
Query: 3030 WMSAR-EAFLAQEDPSGDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSP 2854
W+ + + L + N++S I+KH FD + + +++ + E LI+ +H+
Sbjct: 2793 WLVQKLQVALDENYREPSNLQSKIQKHAAFDAELLSNSPRVQSVIHEGERLIRGDHFAKD 2852
Query: 2853 AVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTE-KFQIAQEENY 2677
+ ++ + W LK A K+ KL ++ F+R DE NWM E + Q++ E+
Sbjct: 2853 EIAQQVQLLEGDWLKLKGASQTKKDKLQQAYDALAFNRSVDEFNNWMDEVELQLSSEDYG 2912
Query: 2676 RDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQ 2497
+D + +K + EA++ + + + Q + E + R +
Sbjct: 2913 KDLAAVSNLLKKHERLEADVAHHGELADQLKQKDEQFFQAEHFLRHE--IHERATVSIRR 2970
Query: 2496 WDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKK 2317
++ L + + L+++ + F+ +D WL E +++ S+D G L SV+ L KK
Sbjct: 2971 YNTLHEPLGIRRENLEDSLSLQQFLRDAEDELQWLAEKQLVAGSQDLGTSLLSVQGLQKK 3030
Query: 2316 HSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDK 2137
H+ LEA++ + + + + ++ ++ ++ F +Q+ + +L+ + ++ +A RR +
Sbjct: 3031 HNSLEAELTSQEPLIQALLQRGQQMIRDNHFASEQLQYKSELLQKQLVQLRDLAAIRRLR 3090
Query: 2136 LSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQ 1957
L A+ F+ + ++ ++W++EK+ ++SS DYGRD VQ ++K + EL + +P
Sbjct: 3091 LLDAVESQLFYVEANEADAWMREKRPVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPS 3150
Query: 1956 VSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFL 1777
+ V L+ I ++ + Q + + L R RL E + +L
Sbjct: 3151 IEKVAKLATGLIE---RNHFDSSNIAEKNAQVGQEYEDLLRLAKERESRLGECKKLFEYL 3207
Query: 1776 GDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTL 1597
+ EE W+ ++ + S+++GE++ V+ L+ ++F +L ++ RV + +GD L
Sbjct: 3208 RETEELHEWVGDQMAVTASEDYGEDVEHVEQLILAFESFVSNLNANEARVEACLERGDRL 3267
Query: 1596 IHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKE 1417
I N + IK + D+ + E++ + R L + D I EK+
Sbjct: 3268 IQENNPYRSSIKSKRDETKQLWEELKDLVHARQDALAGAKQVHVYDRVADETIQLINEKD 3327
Query: 1416 QQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEK 1237
+ SED+G+DL S+Q L K + F++ L + + + + +L IE
Sbjct: 3328 ASLISEDYGQDLESIQALGRKHQVFESELVGIQGQ-VDSVLAEAAKLGEIYPDAKEHIEV 3386
Query: 1236 RHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTD 1057
+ ++ W +L + AR+ +E A W +T
Sbjct: 3387 KRDETVEAWTDLKEKTAARKNKLSQAEQLQSYFDEYRDLIA--------WINEMLAKITA 3438
Query: 1056 PVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALE 877
P NS+ L + + + + +E F + +++ F +E
Sbjct: 3439 PELANSVAGAELLLASTKDHDTEIRTRDETFAKFAANGQQLIK-------EKHFLAHEVE 3491
Query: 876 DTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEMMEA--GGT 703
D + LQ + + L + + E N + F K A W+++ ++ + G +
Sbjct: 3492 DKIKVLQARHELLKHTLNKRREIYELNLDTQL-FLKDAEILEQWISSREPQLKDTKLGDS 3550
Query: 702 LEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERNLILDNRY---TEHSTVGIAQAWDQL 532
+ + D + R K Q EEK ++R +L+ + E + Q ++L
Sbjct: 3551 IPQVEDLLRRHEDFEKTVAAQ----EEKFQAIKRITMLEQLFRHQLEQEKISKLQEKERL 3606
Query: 531 --DQLAMRMQHNLEQQIQARNQSGVSEE 454
++L Q L++ R ++ E
Sbjct: 3607 EKERLEQLKQRELQRLADERRRAEKQHE 3634
Score = 511 bits (1316), Expect = e-142
Identities = 471/2295 (20%), Positives = 948/2295 (40%), Gaps = 57/2295 (2%)
Frame = -1
Query: 7212 ILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTA 7033
I E AD + +R+Q + Y ++ +Q + LE++ F R+ D+ W+ EK +
Sbjct: 942 INENADSVEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKERMI 1001
Query: 7032 QEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEEL 6853
+ + N + K +K F ++ A +K + +D + + H + I R ++
Sbjct: 1002 KSDEGEGVDNAKRKFEK---FITDLSAASKRVEEIDGAVDTFRRQGHSQLDKIIARQRQI 1058
Query: 6852 HALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEIL 6673
H +W + L+ A + F R CDE W+ EK + + DL V+ L
Sbjct: 1059 HQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVITPDLRTVQAL 1118
Query: 6672 QRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATR 6493
QR+ + +EL + ++N + + + +E D + ++ +V D W ++ +
Sbjct: 1119 QRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQDMWQQVQQRGSDL 1178
Query: 6492 KEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAAL 6313
+ + Q FN A LAWI L++D+ RD+ L +KH D+ A
Sbjct: 1179 RNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDLGDDIRAH 1238
Query: 6312 EGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFL 6133
+ + +++ + +L++ P+ AE + + KA +A+ ++ L + L F
Sbjct: 1239 DTEFVEVIQLGKQLSDGKPNMAETV-AVIERLKAEQDAIHRGWAEKQKWLLQCVDLQMFN 1297
Query: 6132 ADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKL 5953
+ + + +A + + L + EA+L+ H + + + A+ + KL
Sbjct: 1298 READKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLDFEKSLMAQDKILKGFSDNADKL 1357
Query: 5952 VEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQE 5773
+ +S + ++ ++ ++ ++ ER+ L + D F + + + W+ +
Sbjct: 1358 ISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKT 1417
Query: 5772 AFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEX 5593
+ + D L ++ ++KH+ FE+ L A E ++ + + L+Q + +V
Sbjct: 1418 RIAGDENYRD-LSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQAGN-RVPEVESR 1475
Query: 5592 XXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARD-DSYLDPTN 5416
+G L+++ ++ +R ++ + E S R D D +
Sbjct: 1476 VADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDSALRSGDVGNDLRS 1535
Query: 5415 IRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDA 5236
+ + K E E+ + ++ ++ STG+ + GHF A +I +++ + +L D
Sbjct: 1536 CKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQQRFKDLRDP 1595
Query: 5235 TNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESD 5056
T ++ AKL E+ N +F ++ W++E S + G++L Q+L KK +E++
Sbjct: 1596 TQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKSNELGQNLHQAQSLHKKHKKLEAE 1655
Query: 5055 FNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQG 4876
H ++ Q ++H + + L+Q + L +R RKL S +
Sbjct: 1656 IKGHQPMINKALVAGQSLISQQHPEREQVESLCQQLEQAWQDLERHCGERSRKLDMSLKA 1715
Query: 4875 NQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSA 4696
Q D + +W+ E+ V ST GRD L+ K + + E+ + + + +
Sbjct: 1716 QQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLLTKHKTIELELDTYSGIVTEMGHS 1775
Query: 4695 ANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWM 4516
M+ H + + K + + L A +R+ L +SL H+Y +++E + W+
Sbjct: 1776 CAAMVAANHPDSKVLAAKQQLIEKMLKSLHKLASQRQGRLMESLYKHEYFLESDEVEQWI 1835
Query: 4515 SEKEPIVGSTDYGKDEDSAEALLK-----KHRA----------------LLSDLEAFKGT 4399
E+E S DYG+D + + L KHR L+ +
Sbjct: 1836 REQEQAASSEDYGQDFEHLQLLQNKFDDLKHRVEVGADRVDQCELLAKKLIDSESPYANE 1895
Query: 4398 IEDLRKQ--------ASQCKYQEQPMGQLG------RDCVLALYDYQEKSPREVSMKKGD 4261
+E ++Q +EQ + G RD AL+ Q+K+ +S + G
Sbjct: 1896 VEKRQEQLRTSWENLLQLLNQREQKLHAAGEIHRFHRDVAEALFRIQDKN-AALSQELGR 1954
Query: 4260 VLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIEPGTAQQHAQQQVNSIGGKQSEIEDKYQ 4081
L A R E ND V + Q ++I +Q ++ +
Sbjct: 1955 DLNSALALLRKHEGFE-NDLVALEAQLQVLVEDSVRLQAKYPSNASAIAQQQDKVVAAWN 2013
Query: 4080 RLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFD 3901
L R +L + L + D+ W + A +E +D L+ + D
Sbjct: 2014 DLKERSTARGDRLAASSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHD 2073
Query: 3900 DFKGDLKANEVRLQEMNQIATALTSVGQ------TETAVRIRQQIEDLNARWRALXXXXX 3739
G+++A E + + +N+++ ++ G E + + + L+A W
Sbjct: 2074 AIYGEIEAREDKFRYLNELSDSMVQTGHYAAADVEEKCAAMLDERQKLHAAWN------- 2126
Query: 3738 XXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLA 3559
L ++ F RD + + + AL S DFG+ + VQ RKH+ ER +
Sbjct: 2127 KKKIMLEQKIDLFCFLRDAKQIDNLSSSQQAALSSSDFGQTVEDVQNKIRKHDEFERLIQ 2186
Query: 3558 ALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQR 3379
+K+ L E +L + + I + + + + ++ R+ KL D+ Y +
Sbjct: 2187 TQEEKVSLLQEHGRKLIEQRHYDSANIQTILQGVLARRQKVKDLCAVRRYKLEDALLYAK 2246
Query: 3378 FLSDYRDLMQWI-ASMNQLVSSQELANDVTGAE---ALLERHQEYRTEIDSRAATFQAFD 3211
F+ D + WI +L + +VT + L++HQ ++ E+ + Q
Sbjct: 2247 FVRDCAEAKYWINEKQKKLEADAASYAEVTNLDEKIKKLQKHQAFQAEVAANQGRIQEIQ 2306
Query: 3210 QFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADT 3031
G LL+ H ++ +I+ ++ V EA +GL R L++ + F ++ +
Sbjct: 2307 DTGVILLSKQHESSPEIKRAIEIVLEAWQGLLAELEQRGRGLEEAQDSLEFNSQLDKIEA 2366
Query: 3030 WMSAREAFLAQEDPSGD--NVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHY-- 2863
W+ +E + D D + +L++K +D D + ++++K + A+ LI
Sbjct: 2367 WIRDKEMMVQASDTGRDLEHCNALMRKLDDVDSDMRVDDQRVKHINQLADKLINQAQVPA 2426
Query: 2862 DSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEK-FQIAQE 2686
D+ +V ++R W L+ AL R LG + + F+RD D+ + + EK ++
Sbjct: 2427 DTQSVDKRRKDFNYNWRQLQGALNAYRALLGGANEIHVFNRDVDDTADRIAEKSLAMSST 2486
Query: 2685 ENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKAL 2506
+ RD ++ ++++A E ++ A +I A LI+ G + + +L+ L
Sbjct: 2487 DTGRDLAAVEALIRREEALERDMSAVKQKIDQHETAAEFLIKKYPERGAQ-HIERKLEEL 2545
Query: 2505 NDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENL 2326
+ W L + ++ L EA F++ VK+LE W+ ++ + + + E
Sbjct: 2546 HKSWGNLQALSVKRQSILNEAYLAHKFVSDVKELELWVNDMIKKMNNTQSPSTINDCETQ 2605
Query: 2325 LKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADR-YDGVKKMATD 2149
L+ H + +I Q+ + +Q + L + Q Q + L+ + + + + ++
Sbjct: 2606 LELHQERKVEIEGRQEAFAGLKQQGEQLSKRPQQQQPDNVRKYLLVLEELHQTLNEAWSE 2665
Query: 2148 RRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELAS 1969
R L++A + F ++ E W+ K+ +++DD G V+ L +KH + L
Sbjct: 2666 RARDLTEAHQLQLFKAQVEQVEIWLANKEAFLNNDDLGDSYTAVERLLKKHDEFEKLL-- 2723
Query: 1968 HEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAF 1789
H V ++ +L + D I++++ + + ++ +L+ R QRL +S
Sbjct: 2724 HADHVDTLQKFANSILEGEPK---DADLIREKLAYILRRKQKLLELSEERKQRLTQSHQL 2780
Query: 1788 QAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINK 1609
Q FL + E + W+ +K Q+ +N+ E + +Q ++KH F +L + RV +I++
Sbjct: 2781 QEFLRSLYEIDRWLVQKLQVALDENYRE-PSNLQSKIQKHAAFDAELLSNSPRVQSVIHE 2839
Query: 1608 GDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWI 1429
G+ LI + I Q+ L ++++ ++ + KL+ L F D +W+
Sbjct: 2840 GERLIRGDHFAKDEIAQQVQLLEGDWLKLKGASQTKKDKLQQAYDALAFNRSVDEFNNWM 2899
Query: 1428 AEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSP 1249
E E Q+ SED+G+DL++V LL K E +A + A E ++ + +Q +EH
Sbjct: 2900 DEVELQLSSEDYGKDLAAVSNLLKKHERLEADV-AHHGELADQLKQKDEQFFQAEHFLRH 2958
Query: 1248 AIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEE 1069
I +R T I+R+ L RR F + A W +
Sbjct: 2959 EIHERATVSIRRYNTLHEPLGIRRENLEDSLSLQ--------QFLRDAEDELQWLAEKQL 3010
Query: 1068 DLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTM 889
SL ++ L+ H + L+S E + L +++ N + +
Sbjct: 3011 VAGSQDLGTSLLSVQGLQKKHNSLEAELTSQEPLIQALLQRGQQMIRDNHFASEQLQYKS 3070
Query: 888 DALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEMMEAG 709
+ L+ L+ + R L + Q F AN AW+ R + +
Sbjct: 3071 ELLQKQLVQLRDLAAIRRLRLLDAVESQ--------LFYVEANEADAWMREKRPVLSSSD 3122
Query: 708 -GTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERNLILDNRYTE----HSTVGIAQA 544
G E + ++K + ++ + EK A L LI N + + Q
Sbjct: 3123 YGRDEVSVQGHQKKLEVLQRELTAFKPSIEKVAKLATGLIERNHFDSSNIAEKNAQVGQE 3182
Query: 543 WDQLDQLAMRMQHNL 499
++ L +LA + L
Sbjct: 3183 YEDLLRLAKERESRL 3197
Score = 503 bits (1294), Expect = e-140
Identities = 491/2306 (21%), Positives = 986/2306 (42%), Gaps = 133/2306 (5%)
Frame = -1
Query: 7119 RLEEARQFQY-FKRDADELNVWILEKLQTAQEENFRDPSNLQAKIQKHEAFEAEVQAHAK 6943
R E+ Q Y F++ + ++ E +Q + + + A ++KHEA A++ A +
Sbjct: 390 RQEKLEQLNYKFEKKSVLREGYLKEMIQVLSDPRYL--RQVDATLKKHEAISADILARVE 447
Query: 6942 TIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQ 6763
+L + + N+ E +++R +E+ A W + + L Q L++ +R+
Sbjct: 448 RFNDLTAMAEELDRENYHGKERVRRREQEVMAKWRQLLELLENQRLNLSQMSNLMNLLRE 507
Query: 6762 CDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQY--RINEINQAADKL 6589
+RE + +ED+G L VE L + L+EL + Y + N+ A
Sbjct: 508 IASTTEAVRELQQQFASEDVGPHLLGVEELLQAHS--LQELQVNTYGETLKRFNRQALPY 565
Query: 6588 VEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKD 6409
H + + ++ D+ +A+ L +A R+ L A F D D +W+ +K
Sbjct: 566 KSSEHKDAALLAQRLADLEEAYSELLRRSAARRARLEEARNFHHFMEDYDNEESWLVDKQ 625
Query: 6408 LALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKL-AETHPDRAEAIHQ 6232
+ +DL V +LQ+KH+ E ++ + + K Q+ +L E HP R+ I
Sbjct: 626 RICKTGITAKDLRAVLSLQQKHKALEDEIKSRKPKSGQMSTAGKRLIGEQHP-RSSEIQS 684
Query: 6231 KNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVA 6052
+ D W AL+ + R+ LE + + ++F D + SW+ + A++ + + D
Sbjct: 685 RIDSLAEHWQALEALVELRRRQLEDAAEAYQFYTDANEAESWLNEKIALVNSRDYGNDEP 744
Query: 6051 GAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGI---------PESPEVQEK---- 5911
A+ALL+ H++ +GE++A + KL++ GI PE PEV+++
Sbjct: 745 SAQALLQRHRDLQGELNAYSGDILNLNQQADKLIKAGICTLELSAAEPELPEVEQEEWVN 804
Query: 5910 --------------LEKLDHEKSSLLGLWEERRILYE---QCMDLQ----LFYRDTEQAE 5794
+EKL+H+K + + + L+ Q M + + + +
Sbjct: 805 ETRLVPKEVWEDEWVEKLEHKKVTETKMLPHVKSLFPFEGQGMKMDKGEVMLLKSKTNDD 864
Query: 5793 TWMNKQEAFLANTDLGDSLDSVE-----------HLIKKHEDFEKSLAAQE----EKINA 5659
W +++ + + + VE +K + +K++ ++ ++I
Sbjct: 865 WWCVRKDNGVEGFVPANYVREVEPRPVACIVPKAEKVKSLQKVKKTILVRQVVPVKRIKP 924
Query: 5658 LDEFATKLIQGQ------HYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFD 5497
+ L+Q + + AD V + R L++S F
Sbjct: 925 VSVAPKPLVQRRTSTQSINENADSVEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFY 984
Query: 5496 RDCDEMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQII 5317
R+CD+ W+ EK + D N + K +K I +L A R+++I +
Sbjct: 985 RECDDFEKWMKEKERMIKSDEGEGVDNAKRKFEKFIT---DLSAASKRVEEIDGAVDTFR 1041
Query: 5316 DSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEG 5137
GH D I R RQ++ +W L +A ++ L A + + FNR ++ + W+SE
Sbjct: 1042 RQGHSQLDKIIARQRQIHQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKML 1101
Query: 5136 QVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQ-----EEEHFNAPV 4972
Q+ + DL +VQ LQ++ +E + D+V+ + L + E+++ NA
Sbjct: 1102 QLDTAVITPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNA-- 1159
Query: 4971 IVRKQE------NLQQRYNALRDPLEKRKRKLGESHQGNQLFRD-IEDELAWIREKEQVA 4813
R+QE +QQR + LR+ + ES G Q+F + + LAWI +
Sbjct: 1160 --RQQEVQDMWQQVQQRGSDLRNRI--------ESEVGQQVFNNSAKVLLAWIDSVKDQL 1209
Query: 4812 GSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLA---PEIRDK 4642
+ RD+ NL+KK L +I HD++ V IQ G L+ P + +
Sbjct: 1210 NADESARDVETANNLLKKHNDLGDDIRAHDTEFVEV-------IQLGKQLSDGKPNMAET 1262
Query: 4641 LAQLR----DNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGK 4474
+A + + I + AEK++ L + + +A++ DA E + + G
Sbjct: 1263 VAVIERLKAEQDAIHRGWAEKQKW-LLQCVDLQMFNREADKIDATTKSHEAFLEYNNLGA 1321
Query: 4473 DEDSAEALLKKH----RALLSDLEAFKGTIEDLRKQASQCKYQEQPMGQLGRDCVL---- 4318
D EA+LK+H ++L++ + KG ++ K S Y + +G R+ VL
Sbjct: 1322 SLDEVEAILKRHLDFEKSLMAQDKILKGFSDNADKLISNDHYDSKYIGD-RRNQVLGKRK 1380
Query: 4317 ALYDYQEKSPREVSMKKGDVLTLLNASNRDWW---KVEVNDRQGFVPAAYVKR------- 4168
A+ D + R + K A + W K + + + + + R
Sbjct: 1381 AVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKTRIAGDENYRDLSNLPRKLQKHQA 1440
Query: 4167 ---------------IEPGTAQQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEA 4033
+ G A A +V + + +++ +++ L+ L E + RKLE+A
Sbjct: 1441 FERELRANEGQLRNVTKDGQALVQAGNRVPEVESRVADLNKRWKDLLTLSEDKGRKLEQA 1500
Query: 4032 CKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEM 3853
+ R D + + ++ ++G DL + L K + ++ + ++ E+
Sbjct: 1501 ASQREHNRSLEDAKKKVDELDSALRSGDVGNDLRSCKDLINKQQILESEITIWDQKVAEL 1560
Query: 3852 NQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDET 3673
+ G A I ++L R++ L +L + +F ++D
Sbjct: 1561 VSTGDDMAHGGHF-NAQNIEAGTKELQQRFKDLRDPTQRRRAKLEESLNYHKFVFELDSE 1619
Query: 3672 RDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKI-KSLDEKANRLRQSHP 3496
WI E A S + G++L Q+L +KH+ +E ++ I K+L + + Q HP
Sbjct: 1620 FQWINEHLPAAKSNELGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALVAGQSLISQQHP 1679
Query: 3495 EAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSS 3316
E EQ+ L ++L + W L R KL S Q++L D ++ W+ N ++ S
Sbjct: 1680 E-REQVESLCQQLEQAWQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERNNVLRS 1738
Query: 3315 QELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVN 3136
E D A LL +H+ E+D+ + ++ ++H + + + Q +
Sbjct: 1739 TEYGRDRDSAAKLLTKHKTIELELDTYSGIVTEMGHSCAAMVAANHPDSKVLAAKQQLIE 1798
Query: 3135 EARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGD--NVESLI 2962
+ K L R+ L + L ++ + ++ + W+ +E + ED D +++ L
Sbjct: 1799 KMLKSLHKLASQRQGRLMESLYKHEYFLESDEVEQWIREQEQAASSEDYGQDFEHLQLLQ 1858
Query: 2961 KKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKR 2782
K +D + +++ +L A+ LI + + V ++++Q+ W L + L Q+
Sbjct: 1859 NKFDDLKHRVEVGADRVDQCELLAKKLIDSESPYANEVEKRQEQLRTSWENLLQLLNQRE 1918
Query: 2781 FKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNIQQKHQKQQAFEAELHANSD 2602
KL + + +F RD E + +K +E RD + +K + FE +L A
Sbjct: 1919 QKLHAAGEIHRFHRDVAEALFRIQDKNAALSQELGRDLNSALALLRKHEGFENDLVALEA 1978
Query: 2601 RIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFM 2422
++ +++ L AK +A++ + + W+ L + +T + RL ++ ++F+
Sbjct: 1979 QLQVLVEDSVRL--QAKYPSNASAIAQQQDKVVAAWNDLKERSTARGDRLAASSDLQTFL 2036
Query: 2421 AAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSL 2242
V+D+ W + LQ+E++ D A L +H + +I A +D+ +NE +DS+
Sbjct: 2037 TDVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEAREDKFRYLNELSDSM 2096
Query: 2241 LENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKK 2062
++ + + E+ + D + ++ L + +++ F RD ++ ++
Sbjct: 2097 VQTGHYAAADVEEKCAAMLDERQKLHAAWNKKKIMLEQKIDLFCFLRDAKQIDNLSSSQQ 2156
Query: 2061 LLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQI 1882
+SS D+G+ + VQN RKH + + + E +VSL++ G +L+ + I
Sbjct: 2157 AALSSSDFGQTVEDVQNKIRKHDEFERLIQTQEEKVSLLQEHGRKLIE---QRHYDSANI 2213
Query: 1881 KKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSD--NFG 1708
+ ++ + +++DL R +L+++ + F+ D E + W+NEKQ+ L +D ++
Sbjct: 2214 QTILQGVLARRQKVKDLCAVRRYKLEDALLYAKFVRDCAEAKYWINEKQKKLEADAASYA 2273
Query: 1707 E--NMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQL--- 1543
E N+ L+KH FQ ++ ++ R+ ++ + G L+ + +P IK+ + +
Sbjct: 2274 EVTNLDEKIKKLQKHQAFQAEVAANQGRIQEIQDTGVILLSKQHESSPEIKRAIEIVLEA 2333
Query: 1542 -RARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQI 1366
+ L E+E G L + L+F + D +E+WI +KE V++ D GRDL
Sbjct: 2334 WQGLLAELEQRGRG----LEEAQDSLEFNSQLDKIEAWIRDKEMMVQASDTGRDLEHCNA 2389
Query: 1365 LLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEH--QQSPAIEKRHTNVIQRWQNLLAH 1192
L+ K + D+ + + + ++ I +L D+L++ + +++KR + W+ L
Sbjct: 2390 LMRKLDDVDSDMRV-DDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYNWRQLQGA 2448
Query: 1191 SEARRX---XXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRA 1021
A R +++ A+K+ +S TD R L + A
Sbjct: 2449 LNAYRALLGGANEIHVFNRDVDDTADRIAEKSLAMSS---------TDTGR--DLAAVEA 2497
Query: 1020 LRDAHGEFQRSLSSAEEDFRQLQD-LDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIK 844
L +R +S+ ++ Q + + IK + + ++ L +W NLQ +
Sbjct: 2498 LIRREEALERDMSAVKQKIDQHETAAEFLIKKYPERGAQHIERKLEELHKSWGNLQALSV 2557
Query: 843 EREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEM--MEAGGTL---EEQLDAV 679
+R+ L + L +F W+ + ++M ++ T+ E QL+
Sbjct: 2558 KRQSILNEAY--------LAHKFVSDVKELELWVNDMIKKMNNTQSPSTINDCETQLELH 2609
Query: 678 ERKAKEIKANKGQLRQIEEKGAMLER 601
+ + EI+ + ++++G L +
Sbjct: 2610 QERKVEIEGRQEAFAGLKQQGEQLSK 2635
Score = 455 bits (1170), Expect = e-126
Identities = 455/2234 (20%), Positives = 916/2234 (40%), Gaps = 59/2234 (2%)
Frame = -1
Query: 7185 QRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQ----EENF 7018
QR ++ YS S +R RLEEAR F +F D D W+++K + + ++
Sbjct: 578 QRLADLEEAYSELLRRSAARRARLEEARNFHHFMEDYDNEESWLVDKQRICKTGITAKDL 637
Query: 7017 RDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWX 6838
R +LQ QKH+A E E+++ + G +I H S I+ R++ L W
Sbjct: 638 RAVLSLQ---QKHKALEDEIKSRKPKSGQMSTAGKRLIGEQHPRSSEIQSRIDSLAEHWQ 694
Query: 6837 XXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFD 6658
+ +L+ A + F +E W+ EK V + D G D + L ++
Sbjct: 695 ALEALVELRRRQLEDAAEAYQFYTDANEAESWLNEKIALVNSRDYGNDEPSAQALLQRHR 754
Query: 6657 DFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLF 6478
D EL + I +NQ ADKL++ G + TL + E
Sbjct: 755 DLQGELNAYSGDILNLNQQADKLIKAG--------------------ICTLELSAAEP-- 792
Query: 6477 GAHQVQRFNRDADETLAWIGEKDLA---LSSDDYGRDLNNVQALQRKHEGTERDLAALEG 6307
E W+ E L + D++ L + + + K + L EG
Sbjct: 793 --------ELPEVEQEEWVNETRLVPKEVWEDEWVEKLEHKKVTETKMLPHVKSLFPFEG 844
Query: 6306 KMLQLEK-EAHKLAETHPDRAEAIHQKND-DTKAAWNALKEKAQHRKDGLERSFQLHRFL 6133
+ ++++K E L D + + N + N ++E + + + L
Sbjct: 845 QGMKMDKGEVMLLKSKTNDDWWCVRKDNGVEGFVPANYVREVEPRPVACIVPKAEKVKSL 904
Query: 6132 ADYRD--LISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQ 5959
+ L+ + +K + K + +S E+ ++ R NQT
Sbjct: 905 QKVKKTILVRQVVPVKRIKPVSVAPKPLVQRRTSTQSINENADSVEKRQQRINQTYD--- 961
Query: 5958 KLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNK 5779
E+QE +K R L E + L FYR+ + E WM +
Sbjct: 962 -----------ELQEMAQK--------------RHALLEDSIHLFGFYRECDDFEKWMKE 996
Query: 5778 QEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVA 5599
+E + +D G+ +D+ + +K E F L+A +++ +D + H D +
Sbjct: 997 KERMI-KSDEGEGVDNAK---RKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDKII 1052
Query: 5598 EXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDP- 5422
R +L+ + + F+R CDE W++EK+ D + + P
Sbjct: 1053 ARQRQIHQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKM-LQLDTAVITPD 1111
Query: 5421 -TNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNEL 5245
++ ++H N E+EL E++++ + G + ++ D++ R ++V ++W ++
Sbjct: 1112 LRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQDMWQQV 1171
Query: 5244 VDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLI 5065
+ ++ +Q FN + + + AW+ ++ Q+ +++ +D+ + NL KK +
Sbjct: 1172 QQRGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDL 1231
Query: 5064 ESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGES 4885
D AH+ + QL +Q + + N V E L+ +A+ ++++ L +
Sbjct: 1232 GDDIRAHDTEFVEVIQLGKQLSDGKP-NMAETVAVIERLKAEQDAIHRGWAEKQKWLLQC 1290
Query: 4884 HQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESV 4705
R+ + A + E N G L V+ ++K+ + D ++
Sbjct: 1291 VDLQMFNREADKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLDFEKSLMAQDKILKGF 1350
Query: 4704 SSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEAD 4525
S A+ +I H+ + I D+ Q+ + +K +A +R+ L S H++ ++A++
Sbjct: 1351 SDNADKLISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEADDLK 1410
Query: 4524 AWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQA---------- 4375
W+ +K I G +Y +D + L+KH+A +L A +G + ++ K
Sbjct: 1411 VWLQDKTRIAGDENY-RDLSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQAGNRV 1469
Query: 4374 --------------------SQCKYQEQPMGQLGRDCVLALYDYQEK-SPREVSMKKGDV 4258
S+ K ++ R+ +L D ++K + +++ GDV
Sbjct: 1470 PEVESRVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDSALRSGDV 1529
Query: 4257 LTLLNASNRDWWKVEVNDRQGFV-PAAYVKRIEPGTAQQHAQQ-QVNSIGGKQSEIEDKY 4084
L + K ++ + + + + + G H +I E++ ++
Sbjct: 1530 GNDLRSCKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQQRF 1589
Query: 4083 QRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKF 3904
+ L + R+ KLEE+ ++ + E + +WI A E+G +L Q + L KK
Sbjct: 1590 KDLRDPTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKSNELGQNLHQAQSLHKKH 1649
Query: 3903 DDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQ 3724
+ ++K ++ + + +L S E ++ + L W+ L +
Sbjct: 1650 KKLEAEIKGHQPMINKALVAGQSLISQQHPERE-QVESLCQQLEQAWQDLERHCGERSRK 1708
Query: 3723 LGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDK 3544
L + + Q++ D E W+ E+++ L S ++GRD S L KH+ +E +L
Sbjct: 1709 LDMSLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLLTKHKTIELELDTYSGI 1768
Query: 3543 IKSLDEK-ANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSD 3367
+ + A + +HP+ ++ + Q+ + + L A+ R+ +L++S + +
Sbjct: 1769 VTEMGHSCAAMVAANHPD-SKVLAAKQQLIEKMLKSLHKLASQRQGRLMESLYKHEYFLE 1827
Query: 3366 YRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLN 3187
++ QWI Q SS++ D + L + + + ++ A + +L++
Sbjct: 1828 SDEVEQWIREQEQAASSEDYGQDFEHLQLLQNKFDDLKHRVEVGADRVDQCELLAKKLID 1887
Query: 3186 SHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAF 3007
S A ++E R + + + + L R L E+ F+RD +A + + A
Sbjct: 1888 SESPYANEVEKRQEQLRTSWENLLQLLNQREQKLHAAGEIHRFHRDVAEALFRIQDKNAA 1947
Query: 3006 LAQE-DPSGDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQ 2830
L+QE ++ +L++KHE F+ + E +++ L + L ++ A+ +++D+
Sbjct: 1948 LSQELGRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSVRLQAKYPSNASAIAQQQDK 2007
Query: 2829 ILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTE-KFQIAQEENYRDPTNIQQ 2653
++ WN LKE + +L S LQ F D +I +W + + + EE+ D
Sbjct: 2008 VVAAWNDLKERSTARGDRLAASSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAGATA 2067
Query: 2652 KHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTT 2473
+ A E+ A D+ + + +++++ A V + A+ D+ L
Sbjct: 2068 LKIQHDAIYGEIEAREDKFRYLNELSDSMVQTGHYAA--ADVEEKCAAMLDERQKLHAAW 2125
Query: 2472 TEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADI 2293
+K L++ F+ K ++ + L S D+G+ + V+N ++KH E I
Sbjct: 2126 NKKKIMLEQKIDLFCFLRDAKQIDNLSSSQQAALSSSDFGQTVEDVQNKIRKHDEFERLI 2185
Query: 2292 VAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVH 2113
+++V + E L+E + I + + R VK + RR KL AL
Sbjct: 2186 QTQEEKVSLLQEHGRKLIEQRHYDSANIQTILQGVLARRQKVKDLCAVRRYKLEDALLYA 2245
Query: 2112 QFFRDIDDEESWI--KEKKLLVSSDDYGRDLPGVQNLRR--KHRRIDTELASHEPQVSLV 1945
+F RD + + WI K+KKL + Y + +++ KH+ E+A+++ ++ +
Sbjct: 2246 KFVRDCAEAKYWINEKQKKLEADAASYAEVTNLDEKIKKLQKHQAFQAEVAANQGRIQEI 2305
Query: 1944 KLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVE 1765
+ G LL E+ +IK+ +E + ++W + R + L+E++ F ++
Sbjct: 2306 QDTGVILLSKQHES---SPEIKRAIEIVLEAWQGLLAELEQRGRGLEEAQDSLEFNSQLD 2362
Query: 1764 EEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNG 1585
+ EAW+ +K+ ++ + + G ++ L++K D D+ + QRV + D LI+
Sbjct: 2363 KIEAWIRDKEMMVQASDTGRDLEHCNALMRKLDDVDSDMRVDDQRVKHINQLADKLINQA 2422
Query: 1584 NHHA--PHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQ 1411
A + +R +++ A L + F D IAEK
Sbjct: 2423 QVPADTQSVDKRRKDFNYNWRQLQGALNAYRALLGGANEIHVFNRDVDDTADRIAEKSLA 2482
Query: 1410 VRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRH 1231
+ S D GRDL++V+ L+ ++EA + ++A + + Q T + + + + IE++
Sbjct: 2483 MSSTDTGRDLAAVEALIRREEALERDMSAVKQKIDQHETAAEFLIKKYPERGAQHIERKL 2542
Query: 1230 TNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLA--FAKKASTFNSWFENAEEDLTD 1057
+ + W NL A S R+ + E YLA F W + + + +
Sbjct: 2543 EELHKSWGNLQALSVKRQ----------SILNEAYLAHKFVSDVKELELWVNDMIKKMNN 2592
Query: 1056 PVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRI--KSFNVGPNPYTWFTMDA 883
+++ + + H E + + +E F L+ ++ + P+ + +
Sbjct: 2593 TQSPSTINDCETQLELHQERKVEIEGRQEAFAGLKQQGEQLSKRPQQQQPDNVRKYLL-V 2651
Query: 882 LEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEMMEAGGT 703
LE+ + L ER ++L HQ Q F WL N +E
Sbjct: 2652 LEELHQTLNEAWSERARDLTEAHQLQ--------LFKAQVEQVEIWLAN--KEAFLNNDD 2701
Query: 702 LEEQLDAVERKAKE 661
L + AVER K+
Sbjct: 2702 LGDSYTAVERLLKK 2715
Score = 328 bits (840), Expect = 2e-87
Identities = 188/525 (35%), Positives = 297/525 (55%), Gaps = 2/525 (0%)
Frame = -1
Query: 7224 QEIRILETADDIHQRRQEVLGHYSI-FKDHSQTKRDRLEEARQFQYFKRDADELNVWILE 7048
Q IR A + Q + E+L + +D + +R RL +A + Q F +A+E + W+ E
Sbjct: 3054 QMIRDNHFASEQLQYKSELLQKQLVQLRDLAAIRRLRLLDAVESQLFYVEANEADAWMRE 3113
Query: 7047 KLQTAQEENF-RDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIK 6871
K ++ RD ++Q +K E + E+ A +I + K +I+ NHF S +I
Sbjct: 3114 KRPVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPSIEKVAKLATGLIERNHFDSSNIA 3173
Query: 6870 KRLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDL 6691
++ ++ + + +L + KL ++R+ +E+ W+ ++ +ED G D+
Sbjct: 3174 EKNAQVGQEYEDLLRLAKERESRLGECKKLFEYLRETEELHEWVGDQMAVTASEDYGEDV 3233
Query: 6690 EHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLN 6511
EHVE L F+ F+ L ++ R+ + D+L++E + I KRD+ W L
Sbjct: 3234 EHVEQLILAFESFVSNLNANEARVEACLERGDRLIQENNPYRSSIKSKRDETKQLWEELK 3293
Query: 6510 TLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTE 6331
L R++ L GA QV ++R ADET+ I EKD +L S+DYG+DL ++QAL RKH+ E
Sbjct: 3294 DLVHARQDALAGAKQVHVYDRVADETIQLINEKDASLISEDYGQDLESIQALGRKHQVFE 3353
Query: 6330 RDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSF 6151
+L ++G++ + EA KL E +PD E I K D+T AW LKEK RK+ L ++
Sbjct: 3354 SELVGIQGQVDSVLAEAAKLGEIYPDAKEHIEVKRDETVEAWTDLKEKTAARKNKLSQAE 3413
Query: 6150 QLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTA 5971
QL + +YRDLI+WI +M A I A ELA VAGAE LL S ++H EI R ++F + A
Sbjct: 3414 QLQSYFDEYRDLIAWINEMLAKITAPELANSVAGAELLLASTKDHDTEIRTRDETFAKFA 3473
Query: 5970 SAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAET 5791
+ GQ+L++ + EV++K++ L L +RR +YE +D QLF +D E E
Sbjct: 3474 ANGQQLIKEKHFLAHEVEDKIKVLQARHELLKHTLNKRREIYELNLDTQLFLKDAEILEQ 3533
Query: 5790 WMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINAL 5656
W++ +E L +T LGDS+ VE L+++HEDFEK++AAQEEK A+
Sbjct: 3534 WISSREPQLKDTKLGDSIPQVEDLLRRHEDFEKTVAAQEEKFQAI 3578
Score = 313 bits (802), Expect = 4e-83
Identities = 227/909 (24%), Positives = 428/909 (46%), Gaps = 5/909 (0%)
Frame = -1
Query: 7200 ADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEEN 7021
AD I ++ +L + S+ ++ RL ++ Q Q F R E++ W+++KLQ A +EN
Sbjct: 2746 ADLIREKLAYILRRKQKLLELSEERKQRLTQSHQLQEFLRSLYEIDRWLVQKLQVALDEN 2805
Query: 7020 FRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALW 6841
+R+PSNLQ+KIQKH AF+AE+ +++ + ++ G +I+ +HFA + I ++++ L W
Sbjct: 2806 YREPSNLQSKIQKHAAFDAELLSNSPRVQSVIHEGERLIRGDHFAKDEIAQQVQLLEGDW 2865
Query: 6840 XXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKF 6661
K KLQQA L F R DE W+ E E +++ED G DL V L +K
Sbjct: 2866 LKLKGASQTKKDKLQQAYDALAFNRSVDEFNNWMDEVELQLSSEDYGKDLAAVSNLLKKH 2925
Query: 6660 DDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGL 6481
+ ++ +H +++ Q ++ + H +I+++ ++ L+ R+E L
Sbjct: 2926 ERLEADVAHHGELADQLKQKDEQFFQAEHFLRHEIHERATVSIRRYNTLHEPLGIRRENL 2985
Query: 6480 FGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKM 6301
+ +Q+F RDA++ L W+ EK L S D G L +VQ LQ+KH E +L + E +
Sbjct: 2986 EDSLSLQQFLRDAEDELQWLAEKQLVAGSQDLGTSLLSVQGLQKKHNSLEAELTSQEPLI 3045
Query: 6300 LQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYR 6121
L + ++ + +E + K++ + L++ A R+ L + + F +
Sbjct: 3046 QALLQRGQQMIRDNHFASEQLQYKSELLQKQLVQLRDLAAIRRLRLLDAVESQLFYVEAN 3105
Query: 6120 DLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMG 5941
+ +W+ + + V+ + + +D + + + + E+ A S + A L+E
Sbjct: 3106 EADAWMREKRPVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPSIEKVAKLATGLIERN 3165
Query: 5940 IPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLA 5761
+S + EK ++ E LL L +ER +C L + R+TE+ W+ Q A A
Sbjct: 3166 HFDSSNIAEKNAQVGQEYEDLLRLAKERESRLGECKKLFEYLRETEELHEWVGDQMAVTA 3225
Query: 5760 NTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXX 5581
+ D G+ ++ VE LI E F +L A E ++ A E +LIQ + +
Sbjct: 3226 SEDYGEDVEHVEQLILAFESFVSNLNANEARVEACLERGDRLIQENNPYRSSIKSKRDET 3285
Query: 5580 XXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEK-LSTARDDSYLDPTNIRGK 5404
R +AL + + +DR DE + I EK S +D D +I+
Sbjct: 3286 KQLWEELKDLVHARQDALAGAKQVHVYDRVADETIQLINEKDASLISEDYGQDLESIQAL 3345
Query: 5403 LQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKK 5224
+KH FE EL + ++D + + ++ + A +HI + + W +L + T +
Sbjct: 3346 GRKHQVFESELVGIQGQVDSVLAEAAKLGEIYPDAKEHIEVKRDETVEAWTDLKEKTAAR 3405
Query: 5223 GAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAH 5044
KL +A Q + D+ AW++E+ ++ + + + + L +++
Sbjct: 3406 KNKLSQAEQLQSYFDEYRDLIAWINEMLAKITAPELANSVAGAELLLASTKDHDTEIRTR 3465
Query: 5043 NDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLF 4864
++ QQ +E+HF A + K + LQ R+ L+ L KR R++ E + QLF
Sbjct: 3466 DETFAKFAANGQQLIKEKHFLAHEVEDKIKVLQARHELLKHTLNKR-REIYELNLDTQLF 3524
Query: 4863 -RDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAAND 4687
+D E WI +E T G + V++L+++ + +A + + +++
Sbjct: 3525 LKDAEILEQWISSREPQLKDTKLGDSIPQVEDLLRRHEDFEKTVAAQEEKFQAIKRIT-- 3582
Query: 4686 MIQQGHFLAPEIRDKLAQLRDNWRILKSKAEK-RRTDLDDSLQAHQYLSDANE--ADAWM 4516
M++Q F ++K+++L++ R+ K + E+ ++ +L + +E +A
Sbjct: 3583 MLEQ-LFRHQLEQEKISKLQEKERLEKERLEQLKQRELQRLADERRRAEKQHEHRQNAAS 3641
Query: 4515 SEKEPIVGS 4489
EK PI S
Sbjct: 3642 QEKTPIFSS 3650
Score = 219 bits (557), Expect = 1e-54
Identities = 252/1272 (19%), Positives = 506/1272 (38%), Gaps = 86/1272 (6%)
Frame = -1
Query: 3999 DLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQ-----IATA 3835
+L WI+ + Q+++ LE ++ F +++ K + + + + I T
Sbjct: 287 NLLSWIRQKTLELEQRDLPNSLEGIQRELLAFKEYRTIEKPPKYKERSEIEALYFTINTL 346
Query: 3834 LTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQ--------RFHRDVD 3679
L ++ Q + Q + D+ W+ L L Q +F +
Sbjct: 347 LKALNQPPYNPQDGQLVNDIEKAWQILEYAEHHREVALRDELLRQEKLEQLNYKFEKKSV 406
Query: 3678 ETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSH 3499
+++E L R LR V A +KHE + D+ A ++ L A L + +
Sbjct: 407 LREGYLKEMIQVLSDP---RYLRQVDATLKKHEAISADILARVERFNDLTAMAEELDREN 463
Query: 3498 PEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVS 3319
E++ ++E+ +W +L N++ L + L + + + + Q +
Sbjct: 464 YHGKERVRRREQEVMAKWRQLLELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQFA 523
Query: 3318 SQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGV 3139
S+++ + G E LL+ H ++++ T + F++ +S H A + RL +
Sbjct: 524 SEDVGPHLLGVEELLQAHSLQELQVNTYGETLKRFNRQALPYKSSEHKDAALLAQRLADL 583
Query: 3138 NEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGD--NVESL 2965
EA L ARR L++ F D + ++W+ ++ + D V SL
Sbjct: 584 EEAYSELLRRSAARRARLEEARNFHHFMEDYDNEESWLVDKQRICKTGITAKDLRAVLSL 643
Query: 2964 IKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQK 2785
+KH+ + I +++ K + + LI H S + + D + + W L+ + +
Sbjct: 644 QQKHKALEDEIKSRKPKSGQMSTAGKRLIGEQHPRSSEIQSRIDSLAEHWQALEALVELR 703
Query: 2784 RFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENY-RDPTNIQQKHQKQQAFEAELHAN 2608
R +L ++ QF DA+E E+W+ EK + +Y D + Q Q+ + + EL+A
Sbjct: 704 RRQLEDAAEAYQFYTDANEAESWLNEKIALVNSRDYGNDEPSAQALLQRHRDLQGELNAY 763
Query: 2607 SDRIAAIIQAGNNLIENAKCGGGEAAVSARL-----------------KALNDQW----- 2494
S I + Q + LI+ C +A L + D+W
Sbjct: 764 SGDILNLNQQADKLIKAGICTLELSAAEPELPEVEQEEWVNETRLVPKEVWEDEWVEKLE 823
Query: 2493 -------------------------------DLLVKTTTEKSYRLKEANKQKSFMAAVKD 2407
LL T + + +++ N + F+ A
Sbjct: 824 HKKVTETKMLPHVKSLFPFEGQGMKMDKGEVMLLKSKTNDDWWCVRKDNGVEGFVPANYV 883
Query: 2406 LEFWLGEVEILLQSEDYGKDLASVENLL-----------KKHSLLEADIVAHQDRVGEMN 2260
E V ++ + K L V+ + K S+ +V + +N
Sbjct: 884 REVEPRPVACIVPKAEKVKSLQKVKKTILVRQVVPVKRIKPVSVAPKPLVQRRTSTQSIN 943
Query: 2259 EQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEES 2080
E ADS + +R++ I YD +++MA R L ++++ F+R+ DD E
Sbjct: 944 ENADS-----------VEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEK 992
Query: 2079 WIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAG 1900
W+KEK+ ++ SD+ GV N +RK + T+L++ +V + + R
Sbjct: 993 WMKEKERMIKSDEG----EGVDNAKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQ- 1047
Query: 1899 VGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGS 1720
D+I R + Q W ++ + R + L+ + + + F +E + WM+EK L +
Sbjct: 1048 --LDKIIARQRQIHQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDT 1105
Query: 1719 DNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLR 1540
++ VQ L ++H + +L + +V + G+++ + ++ R +++
Sbjct: 1106 AVITPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQ 1165
Query: 1539 ARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILL 1360
+++ ++ F V+ +WI + Q+ +++ RD+ + LL
Sbjct: 1166 DMWQQVQQRGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLL 1225
Query: 1359 TKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEAR 1180
K + A + E ++ + +L QL + + + VI+R L A +A
Sbjct: 1226 KKHNDLGDDIRAHDTEFVE-VIQLGKQLSDGKPNMAETVA-----VIER---LKAEQDAI 1276
Query: 1179 RXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGE 1000
Q +L + F ++A ++ ++ E L SL+E+ A+ H +
Sbjct: 1277 HRGWAEKQKWLLQCVDLQM-FNREADKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLD 1335
Query: 999 FQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAR 820
F++SL + ++ + D ++ S + + Y + + ++ +K+R A
Sbjct: 1336 FEKSLMAQDKILKGFSDNADKLISNDHYDSKY----IGDRRNQVLGKRKAVKDR----AF 1387
Query: 819 EHQRQEENDKLRREFAKLANAFHAWLTN-TR---QEMMEAGGTLEEQLDAVERKAKEIKA 652
E +R + K +FA A+ WL + TR E L +L + +E++A
Sbjct: 1388 ERKRLLQASKDFHKFAAEADDLKVWLQDKTRIAGDENYRDLSNLPRKLQKHQAFERELRA 1447
Query: 651 NKGQLRQIEEKGAMLERNLILDNRY--TEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQAR 478
N+GQLR + + G L + NR E + + W L L+ LEQ R
Sbjct: 1448 NEGQLRNVTKDGQALVQ---AGNRVPEVESRVADLNKRWKDLLTLSEDKGRKLEQAASQR 1504
Query: 477 NQSGVSEEALRE 442
+ E+A ++
Sbjct: 1505 EHNRSLEDAKKK 1516
Score = 145 bits (366), Expect = 1e-32
Identities = 99/418 (23%), Positives = 192/418 (45%)
Frame = -1
Query: 2838 RDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNI 2659
RD++L + E L Q +K + L+ E ++ E Q+ + Y +
Sbjct: 385 RDELLRQ-----EKLEQLNYKFEKKSVLR---------EGYLKEMIQVLSDPRYLRQVDA 430
Query: 2658 QQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVK 2479
K K +A A++ A +R + L + + G+ V R + + +W L++
Sbjct: 431 TLK--KHEAISADILARVERFNDLTAMAEEL--DRENYHGKERVRRREQEVMAKWRQLLE 486
Query: 2478 TTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEA 2299
+ L + + + + + + E++ SED G L VE LL+ HSL E
Sbjct: 487 LLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQFASEDVGPHLLGVEELLQAHSLQEL 546
Query: 2298 DIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALN 2119
+ + + + N QA ++ +A+R + + Y + + + RR +L +A N
Sbjct: 547 QVNTYGETLKRFNRQALPYKSSEHKDAALLAQRLADLEEAYSELLRRSAARRARLEEARN 606
Query: 2118 VHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKL 1939
H F D D+EESW+ +K+ + + +DL V +L++KH+ ++ E+ S +P+ +
Sbjct: 607 FHHFMEDYDNEESWLVDKQRICKTGITAKDLRAVLSLQQKHKALEDEIKSRKPKSGQMST 666
Query: 1938 KGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEE 1759
G+ L+ E +I+ R++ L + W + L R ++L+++ F D E
Sbjct: 667 AGKRLI---GEQHPRSSEIQSRIDSLAEHWQALEALVELRRRQLEDAAEAYQFYTDANEA 723
Query: 1758 EAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNG 1585
E+W+NEK ++ S ++G + Q LL++H Q +L + + +L + D LI G
Sbjct: 724 ESWLNEKIALVNSRDYGNDEPSAQALLQRHRDLQGELNAYSGDILNLNQQADKLIKAG 781
Score = 137 bits (344), Expect = 5e-30
Identities = 120/502 (23%), Positives = 222/502 (43%), Gaps = 20/502 (3%)
Frame = -1
Query: 3360 DLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRT-----------EIDSRAATFQAF 3214
+L+ WI + ++L N + G + L +EYRT EI++ T
Sbjct: 287 NLLSWIRQKTLELEQRDLPNSLEGIQRELLAFKEYRTIEKPPKYKERSEIEALYFTINTL 346
Query: 3213 DQFGNQLLNSHH--YAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQ 3040
+ NQ + DIE Q + A E A R +L Q QL Y+ ++
Sbjct: 347 LKALNQPPYNPQDGQLVNDIEKAWQILEYAEHHREVA--LRDELLRQEKLEQLNYKFEKK 404
Query: 3039 ADTWMSAREAFLAQ-----EDPSG-DNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLI 2878
+ RE +L + DP V++ +KKHE I + E+ L AE L
Sbjct: 405 S----VLREGYLKEMIQVLSDPRYLRQVDATLKKHEAISADILARVERFNDLTAMAEELD 460
Query: 2877 KNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTE-KF 2701
+ N++ V R+ +++ +W L E L +R L + L R+ + E +
Sbjct: 461 RENYHGKERVRRREQEVMAKWRQLLELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQ 520
Query: 2700 QIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSA 2521
Q A E+ +++ Q E +++ + + + L + A ++
Sbjct: 521 QFASEDVGPHLLGVEELLQAHSLQELQVNTYGETLKRFNRQA--LPYKSSEHKDAALLAQ 578
Query: 2520 RLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLA 2341
RL L + + L++ + + RL+EA FM + E WL + + + ++ KDL
Sbjct: 579 RLADLEEAYSELLRRSAARRARLEEARNFHHFMEDYDNEESWLVDKQRICKTGITAKDLR 638
Query: 2340 SVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKK 2161
+V +L +KH LE +I + + + G+M+ L+ + +I R +A+ + ++
Sbjct: 639 AVLSLQQKHKALEDEIKSRKPKSGQMSTAGKRLIGEQHPRSSEIQSRIDSLAEHWQALEA 698
Query: 2160 MATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDT 1981
+ RR +L A +QF+ D ++ ESW+ EK LV+S DYG D P Q L ++HR +
Sbjct: 699 LVELRRRQLEDAAEAYQFYTDANEAESWLNEKIALVNSRDYGNDEPSAQALLQRHRDLQG 758
Query: 1980 ELASHEPQVSLVKLKGEELLRS 1915
EL ++ + + + ++L+++
Sbjct: 759 ELNAYSGDILNLNQQADKLIKA 780
Score = 95.9 bits (237), Expect = 1e-17
Identities = 92/499 (18%), Positives = 195/499 (38%), Gaps = 17/499 (3%)
Frame = -1
Query: 6753 ILYWIREKETYVTAEDMGMDLEHVEILQRKFDDF--------LKELGNHQYRINEINQAA 6598
+L WIR+K + D+ LE ++ F ++ KE + IN
Sbjct: 288 LLSWIRQKTLELEQRDLPNSLEGIQRELLAFKEYRTIEKPPKYKERSEIEALYFTINTLL 347
Query: 6597 DKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATR----KEGLFGAHQVQRFNRDADETL 6430
L + ++ D + +D+ AW L R ++ L ++++ N ++
Sbjct: 348 KALNQPPYNPQDG--QLVNDIEKAWQILEYAEHHREVALRDELLRQEKLEQLNYKFEKKS 405
Query: 6429 A----WIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAET 6262
++ E LS Y L V A +KHE D+ A + L A +L
Sbjct: 406 VLREGYLKEMIQVLSDPRY---LRQVDATLKKHEAISADILARVERFNDLTAMAEELDRE 462
Query: 6261 HPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVI 6082
+ E + ++ + A W L E ++++ L + L L + + +++
Sbjct: 463 NYHGKERVRRREQEVMAKWRQLLELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQF 522
Query: 6081 GADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEK 5902
++++ + G E LL++H + +++ ++ + ++ + ++L
Sbjct: 523 ASEDVGPHLLGVEELLQAHSLQELQVNTYGETLKRFNRQALPYKSSEHKDAALLAQRLAD 582
Query: 5901 LDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEH 5722
L+ S LL RR E+ + F D + E+W+ ++ L +V
Sbjct: 583 LEEAYSELLRRSAARRARLEEARNFHHFMEDYDNEESWLVDKQRICKTGITAKDLRAVLS 642
Query: 5721 LIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXX 5542
L +KH+ E + +++ K + +LI QH + ++
Sbjct: 643 LQQKHKALEDEIKSRKPKSGQMSTAGKRLIGEQHPRSSEIQSRIDSLAEHWQALEALVEL 702
Query: 5541 RGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSY-LDPTNIRGKLQKHINFEQELKA 5365
R L+++ + F D +E SW+ EK++ Y D + + LQ+H + + EL A
Sbjct: 703 RRRQLEDAAEAYQFYTDANEAESWLNEKIALVNSRDYGNDEPSAQALLQRHRDLQGELNA 762
Query: 5364 NENRLDDIRSTGEQIIDSG 5308
+ ++ +++I +G
Sbjct: 763 YSGDILNLNQQADKLIKAG 781
Score = 38.9 bits (89), Expect = 1.9
Identities = 57/242 (23%), Positives = 94/242 (38%), Gaps = 16/242 (6%)
Frame = -1
Query: 1092 SWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQ--------RSLSSAEEDFRQLQDLDRR 937
SW +L NSLE I+ A E++ + S E + + L
Sbjct: 290 SWIRQKTLELEQRDLPNSLEGIQRELLAFKEYRTIEKPPKYKERSEIEALYFTINTL--- 346
Query: 936 IKSFNVGP-NPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLAN 760
+K+ N P NP ++ +E W+ L+ RE L E RQE+ ++L +F K +
Sbjct: 347 LKALNQPPYNPQDGQLVNDIEKAWQILEYAEHHREVALRDELLRQEKLEQLNYKFEKKSV 406
Query: 759 AFHAWLTNTRQEMMEAGGTLEEQLDAVERKAKEIKAN-KGQLRQIEEKGAM---LERNLI 592
+L Q + + Q+DA +K + I A+ ++ + + AM L+R
Sbjct: 407 LREGYLKEMIQVLSDP--RYLRQVDATLKKHEAISADILARVERFNDLTAMAEELDRENY 464
Query: 591 LDNRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARN---QSGVSEEALREFSMMFKH 421
+ W QL +L + NL Q N + + EA+RE F
Sbjct: 465 HGKERVRRREQEVMAKWRQLLELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQFAS 524
Query: 420 FD 415
D
Sbjct: 525 ED 526
>gi|38075498|ref|XP_359378.1| similar to Spectrin alpha chain, brain
(Spectrin, non-erythroid alpha chain) (Alpha-II spectrin)
(Fodrin alpha chain) [Mus musculus]
Length = 563
Score = 709 bits (1830), Expect = 0.0
Identities = 344/525 (65%), Positives = 423/525 (80%)
Frame = -1
Query: 1584 NHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVR 1405
NHH +I + L ++ ++E A R AKL +NSA+LQF WK DVVESWI EKE ++
Sbjct: 38 NHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLK 97
Query: 1404 SEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTN 1225
++D+GRDLSSVQ LLTKQE FDAGL AF+ EGI IT LKDQL++++H QS AIE RH +
Sbjct: 98 TDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHAS 157
Query: 1224 VIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRC 1045
+++RW LLA+S R+ ++E+L+L FAKKAS FNSWFENAEEDLTDPVRC
Sbjct: 158 LMKRWTQLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRC 217
Query: 1044 NSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWR 865
NSLEEI+ALR+AH F+ SLSSA+ DF QL +LDR+IKSF V NPYTWFTM+ALE+TWR
Sbjct: 218 NSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFTMEALEETWR 277
Query: 864 NLQRIIKEREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEMMEAGGTLEEQLD 685
NLQ+IIKERE EL +E +RQEENDKLR+EFA+ ANAFH W+ TR M+E GTLE QL+
Sbjct: 278 NLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRSCMVEESGTLESQLE 337
Query: 684 AVERKAKEIKANKGQLRQIEEKGAMLERNLILDNRYTEHSTVGIAQAWDQLDQLAMRMQH 505
A +RK +EI+A + QL++IE+ GA +E LILDN+YTEHSTVG+AQ WDQLDQL MRMQH
Sbjct: 338 ATKRKHQEIRAMRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQQWDQLDQLGMRMQH 397
Query: 504 NLEQQIQARNQSGVSEEALREFSMMFKHFDKEKTGRLDHQQFKSCLRALGYDLPMVDEGQ 325
NLEQQIQARN +GV+EEAL+EFSMMFKHFDK+K+GRL+HQ+FKSCLR+LGYDLPMV+EG+
Sbjct: 398 NLEQQIQARNTTGVTEEALKEFSMMFKHFDKDKSGRLNHQEFKSCLRSLGYDLPMVEEGE 457
Query: 324 PEPEFQRILDIVDPNRDGYVTLQEYMAFMISKETENIQSSEEIEMAFRALSKEFRPYVTA 145
P+PEF+ ILD VDPNRDG+V+LQEYMAFMIS+ETEN++SSEEIE AFRALS E +PYVT
Sbjct: 458 PDPEFEAILDTVDPNRDGHVSLQEYMAFMISRETENVKSSEEIESAFRALSSEGKPYVTK 517
Query: 144 EELYANLTPEQAEFCIRRMKPYMDAISGRSIQGGLDYEQFVHALF 10
EELY NLT EQA++C+ MKPY+D GR + DY +F +LF
Sbjct: 518 EELYQNLTREQADYCVSHMKPYVDG-KGRELPTAFDYVEFTRSLF 561
Score = 94.7 bits (234), Expect = 3e-17
Identities = 81/393 (20%), Positives = 165/393 (41%), Gaps = 13/393 (3%)
Frame = -1
Query: 1893 EDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDN 1714
E+ I +M+ L + R +LDE+ AF F + E+W+ EK+ L +D+
Sbjct: 41 EENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDD 100
Query: 1713 FGENMAGVQGLLKKHDTFQVDLELHKQR-VADLINKGDTLIHNGNHHAPHIKQRCDQLRA 1537
+G +++ VQ LL K +TF L+ +Q +A++ D L+ + + I+ R L
Sbjct: 101 YGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHASLMK 160
Query: 1536 RLIEIESMAEGRLAKLRD--------NSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDL 1381
R ++ + + R KL + +L F K SW E+ + L
Sbjct: 161 RWTQLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSL 220
Query: 1380 SSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNL 1201
++ L +AF + L++ + + ++ EL Q+ S +P + + W+NL
Sbjct: 221 EEIKALREAHDAFRSSLSSAQAD-FNQLAELDRQIKSFRVASNPYTWFTMEALEETWRNL 279
Query: 1200 LAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLE-EIR 1024
+ R + ++L FA+ A+ F+ W + + + +LE ++
Sbjct: 280 QKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRSCMVE--ESGTLESQLE 337
Query: 1023 ALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIK 844
A + H E + + ++++DL ++ + N YT + L W L ++
Sbjct: 338 ATKRKHQE----IRAMRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQQWDQLDQLGM 393
Query: 843 EREQELAREHQRQEE---NDKLRREFAKLANAF 754
+ L ++ Q + ++ +EF+ + F
Sbjct: 394 RMQHNLEQQIQARNTTGVTEEALKEFSMMFKHF 426
Score = 82.8 bits (203), Expect = 1e-13
Identities = 86/337 (25%), Positives = 141/337 (41%), Gaps = 34/337 (10%)
Frame = -1
Query: 5295 DHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDY 5116
++I +++ +N ++L A ++ AKL E QFN + VE+W+ E E + ++DY
Sbjct: 42 ENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDY 101
Query: 5115 GKDLVSVQNLQKKIGLIESDFNA-HNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQR 4939
G+DL SVQ L K ++ A + + I L Q +H + I + +L +R
Sbjct: 102 GRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHASLMKR 161
Query: 4938 YNALRDPLEKRKRKLGESHQGNQLFRDIEDEL-----------AWIREKEQVAGSTNRGR 4792
+ L RK+KL E+ FR +ED +W E+ R
Sbjct: 162 WTQLLANSATRKKKLLEAQSH---FRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCN 218
Query: 4791 DLIGVQNL----------IKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDK 4642
L ++ L + QA ++A D QI+S A+N P
Sbjct: 219 SLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASN----------PYTWFT 268
Query: 4641 LAQLRDNWRILKS---------KAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGS 4489
+ L + WR L+ + E+RR + +D L+ ++ AN W+ E +
Sbjct: 269 MEALEETWRNLQKIIKERELELQKEQRRQEENDKLR-QEFAQHANAFHQWIQETRSCM-V 326
Query: 4488 TDYGKDEDSAEALLKKH---RALLSDLEAFKGTIEDL 4387
+ G E EA +KH RA+ S L+ IEDL
Sbjct: 327 EESGTLESQLEATKRKHQEIRAMRSQLK----KIEDL 359
Score = 79.7 bits (195), Expect = 1e-12
Identities = 89/389 (22%), Positives = 166/389 (41%), Gaps = 37/389 (9%)
Frame = -1
Query: 3798 IRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGR 3619
I +++ LN + L +L +F+ D WI EK+++L ++D+GR
Sbjct: 44 ISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGR 103
Query: 3618 DLRSVQALQRKHEGVERDLAALGDK-IKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWN 3442
DL SVQ L K E + L A + I ++ ++L + ++ I L ++W
Sbjct: 104 DLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHASLMKRWT 163
Query: 3441 RLTSKANNRKEKLLDSYDYQRFLSDY--------RDLMQWIASMNQLVSSQELANDVTGA 3286
+L + + RK+KLL++ + R + D W + + ++ N +
Sbjct: 164 QLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEI 223
Query: 3285 EALLERHQEYRTEIDSRAATFQAFDQFGNQL----LNSHHYAAGDIENRLQGVNEARKGL 3118
+AL E H +R+ + S A F + Q+ + S+ Y +E L
Sbjct: 224 KALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFTME-----------AL 272
Query: 3117 EDAWVARRNIL-DQCLELQLFYRDCEQAD--------------TWMSAREAFLAQEDPSG 2983
E+ W + I+ ++ LELQ R E+ D W+ + + +E +
Sbjct: 273 EETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRSCMVEESGTL 332
Query: 2982 DN-VESLIKKHEDFDKAINTQEEKIKGL-KLFAESLIKNNHYDSPAVT------RKRDQI 2827
++ +E+ +KH++ +A+ +Q +KI+ L E+LI +N Y + + DQ+
Sbjct: 333 ESQLEATKRKHQEI-RAMRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQQWDQLDQL 391
Query: 2826 LDRWNGLKEALIQKRFKLG-ESQTLQQFS 2743
R E IQ R G + L++FS
Sbjct: 392 GMRMQHNLEQQIQARNTTGVTEEALKEFS 420
Score = 75.1 bits (183), Expect = 2e-11
Identities = 78/357 (21%), Positives = 148/357 (40%), Gaps = 25/357 (7%)
Frame = -1
Query: 2538 EAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSED 2359
E +S+++K LN + L K ++ +L E + F +E W+GE E L+++D
Sbjct: 41 EENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDD 100
Query: 2358 YGKDLASVENLLKKHSLLEADIVA-HQDRVGEMNEQADSLLENDQFQGQQIAERRKLIAD 2182
YG+DL+SV+ LL K +A + A Q+ + + D LL Q + I R +
Sbjct: 101 YGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHASLMK 160
Query: 2181 RYDGVKKMATDRRDKLSKALNVHQFFRDIDD-----------EESWIKEKKLLVSSDDYG 2035
R+ + + R+ KL L FR ++D SW + + ++
Sbjct: 161 RWTQLLANSATRKKKL---LEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRC 217
Query: 2034 RDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIK-KRMEDLE 1858
L ++ LR H + L+S + + + EL R V + ME LE
Sbjct: 218 NSLEEIKALREAHDAFRSSLSSAQADFNQL----AELDRQIKSFRVASNPYTWFTMEALE 273
Query: 1857 QSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEA--------WMNEKQQILGSDNFGEN 1702
++W ++ + R L + + Q + +E A W+ E + + ++ G
Sbjct: 274 ETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRSCMVEES-GTL 332
Query: 1701 MAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPH----IKQRCDQL 1543
+ ++ +KH + + +++ DL + + N + H + Q+ DQL
Sbjct: 333 ESQLEATKRKHQEIRA-MRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQQWDQL 388
Score = 72.8 bits (177), Expect = 1e-10
Identities = 77/358 (21%), Positives = 143/358 (39%), Gaps = 17/358 (4%)
Frame = -1
Query: 6678 ILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAA 6499
++ + + L+ G++ ++ + H E + I K +N L AA
Sbjct: 5 LVANESEKLLQTRGDYVVMLSALPCTNSPSFTNNHHE-ENISSKMKGLNGKVSDLEKAAA 63
Query: 6498 TRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLA 6319
RK L +FN AD +WIGEK+ +L +DDYGRDL++VQ L K E + L
Sbjct: 64 QRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQ 123
Query: 6318 ALEGK-MLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLH 6142
A + + + + +L +++AI ++ W L + RK L +
Sbjct: 124 AFQQEGIANITALKDQLLAAKHIQSKAIEARHASLMKRWTQLLANSATRKKKLLEAQSHF 183
Query: 6141 RFLADY--------RDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADS 5986
R + D SW + + + + +AL E+H + + +
Sbjct: 184 RKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQAD 243
Query: 5985 FNQTASAGQKLVEMGIPESPEVQEKLEKLDHE--------KSSLLGLWEERRILYEQCMD 5830
FNQ A +++ + +P +E L+ K L L +E+R E
Sbjct: 244 FNQLAELDRQIKSFRVASNPYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKL 303
Query: 5829 LQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINAL 5656
Q F + W+ + + + + G +E +KH++ +++ +Q +KI L
Sbjct: 304 RQEFAQHANAFHQWIQETRSCMVE-ESGTLESQLEATKRKHQEI-RAMRSQLKKIEDL 359
Score = 64.3 bits (155), Expect = 4e-08
Identities = 86/388 (22%), Positives = 163/388 (41%), Gaps = 30/388 (7%)
Frame = -1
Query: 2874 NNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQI 2695
NNH++ ++ K + + + L++A Q++ KL E+ QF+ AD +E+W+ EK
Sbjct: 37 NNHHEEN-ISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENS 95
Query: 2694 AQEENY-RDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSAR 2518
+ ++Y RD +++Q KQ+ F+A L A A I A + + AK + A+ AR
Sbjct: 96 LKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSK-AIEAR 154
Query: 2517 LKALNDQWDLLVKTTTEKSYRLKEANKQ--------KSFMAAVKDLEFWLGEVEILLQSE 2362
+L +W L+ + + +L EA +F W E L
Sbjct: 155 HASLMKRWTQLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDP 214
Query: 2361 DYGKDLASVENLLKKHSLLEADIVAHQ---DRVGEMNEQADSL--------------LEN 2233
L ++ L + H + + + Q +++ E++ Q S LE
Sbjct: 215 VRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFTMEALEE 274
Query: 2232 DQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSK--ALNVHQFFRDIDDEESWIKEKKL 2059
Q+I + R+L + ++ + DKL + A + + F + I + S + E+
Sbjct: 275 TWRNLQKIIKERELELQK----EQRRQEENDKLRQEFAQHANAFHQWIQETRSCMVEESG 330
Query: 2058 LVSS--DDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQ 1885
+ S + R ++ +R + ++I+ A+ E + L E A+ DQ
Sbjct: 331 TLESQLEATKRKHQEIRAMRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQQWDQLDQ 390
Query: 1884 IKKRMEDLEQSWGQIRDLTGNRHQRLDE 1801
+ RM+ + Q R+ TG + L E
Sbjct: 391 LGMRMQHNLEQQIQARNTTGVTEEALKE 418
Score = 62.0 bits (149), Expect = 2e-07
Identities = 71/325 (21%), Positives = 132/325 (39%), Gaps = 28/325 (8%)
Frame = -1
Query: 3189 NSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREA 3010
N+HH +I ++++G+N LE A R+ LD+ F + ++W+ +E
Sbjct: 37 NNHHEE--NISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKEN 94
Query: 3009 FLAQEDPSGD--NVESLIKKHEDFDKAINT-QEEKIKGLKLFAESLIKNNHYDSPAVTRK 2839
L +D D +V++L+ K E FD + Q+E I + + L+ H S A+ +
Sbjct: 95 SLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEAR 154
Query: 2838 RDQILDRWNGLKEALIQKRFKLGESQT--------LQQFSRDADEIENWMTEKFQIAQEE 2683
++ RW L ++ KL E+Q+ F++ A +W EE
Sbjct: 155 HASLMKRWTQLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFEN-----AEE 209
Query: 2682 NYRDPT------NIQQKHQKQQAFEAEL---HANSDRIAAIIQAGNNLIENAKCGGGEAA 2530
+ DP I+ + AF + L A+ +++A + + I++ +
Sbjct: 210 DLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAEL----DRQIKSFRVASNPYT 265
Query: 2529 VSARLKALNDQWDLLVKTTTEKSYRL-KEANKQ-------KSFMAAVKDLEFWLGEVEIL 2374
++AL + W L K E+ L KE +Q + F W+ E
Sbjct: 266 WFT-MEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRSC 324
Query: 2373 LQSEDYGKDLASVENLLKKHSLLEA 2299
+ E+ G + +E +KH + A
Sbjct: 325 M-VEESGTLESQLEATKRKHQEIRA 348
Score = 57.0 bits (136), Expect = 7e-06
Identities = 53/225 (23%), Positives = 89/225 (39%), Gaps = 9/225 (4%)
Frame = -1
Query: 6939 IANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQC 6760
++ L T + +NH E+I +++ L+ + KL + L F +
Sbjct: 24 LSALPCTNSPSFTNNHH-EENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKA 82
Query: 6759 DEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYR-INEINQAADKLVE 6583
D + WI EKE + +D G DL V+ L K + F L Q I I D+L+
Sbjct: 83 DVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLA 142
Query: 6582 EGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQR--------FNRDADETLA 6427
H + I + + W +L +ATRK+ L A R F + A +
Sbjct: 143 AKHIQSKAIEARHASLMKRWTQLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASAFNS 202
Query: 6426 WIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQL 6292
W + L+ L ++AL+ H+ L++ + QL
Sbjct: 203 WFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQL 247
Score = 46.6 bits (109), Expect = 0.009
Identities = 64/346 (18%), Positives = 134/346 (38%), Gaps = 21/346 (6%)
Frame = -1
Query: 5502 FDRDCDEMVSWITEKLSTARDDSY-LDPTNIRGKLQKHINFEQELKA-NENRLDDIRSTG 5329
F+ D + SWI EK ++ + D Y D ++++ L K F+ L+A + + +I +
Sbjct: 78 FNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALK 137
Query: 5328 EQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDV----- 5164
+Q++ + H + I R + W +L+ + + KL EA Q R +ED+
Sbjct: 138 DQLLAAKHIQSKAIEARHASLMKRWTQLLANSATRKKKLLEA---QSHFRKVEDLFLTFA 194
Query: 5163 ------EAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQF 5002
+W E + L ++ L++ S ++ + + +L +Q
Sbjct: 195 KKASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQI 254
Query: 5001 QEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELA------ 4840
+ + P E L++ + L+ +++R+ +L + + + + E A
Sbjct: 255 KSFRVASNPYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAF 314
Query: 4839 --WIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHF 4666
WI+E L K++ I + + +IE + +A + + +
Sbjct: 315 HQWIQETRSC--MVEESGTLESQLEATKRKHQEIRAMRSQLKKIEDLGAAMEEALILDNK 372
Query: 4665 LAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEA 4528
LAQ W L + + +L+ +QA EA
Sbjct: 373 YTEHSTVGLAQ---QWDQLDQLGMRMQHNLEQQIQARNTTGVTEEA 415
>gi|38051869|gb|AAH60504.1| Spna2 protein [Mus musculus]
Length = 488
Score = 665 bits (1715), Expect = 0.0
Identities = 325/486 (66%), Positives = 396/486 (80%), Gaps = 6/486 (1%)
Frame = -1
Query: 1449 DVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVS 1270
DVVESWI EKE ++++D+GRDLSSVQ LLTKQE FDAGL AF+ EGI IT LKDQL++
Sbjct: 2 DVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLA 61
Query: 1269 SEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNS 1090
++H QS AIE RH ++++RW LLA+S R+ ++E+L+L FAKKAS FNS
Sbjct: 62 AKHIQSKAIEARHASLMKRWTQLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASAFNS 121
Query: 1089 WFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPN 910
WFENAEEDLTDPVRCNSLEEI+ALR+AH F+ SLSSA+ DF QL +LDR+IKSF V N
Sbjct: 122 WFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASN 181
Query: 909 PYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTR 730
PYTWFTM+ALE+TWRNLQ+IIKERE EL +E +RQEENDKLR+EFA+ ANAFH W+ TR
Sbjct: 182 PYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETR 241
Query: 729 QE------MMEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERNLILDNRYTEH 568
M+E GTLE QL+A +RK +EI+A + QL++IE+ GA +E LILDN+YTEH
Sbjct: 242 TYLLDGSCMVEESGTLESQLEATKRKHQEIRAMRSQLKKIEDLGAAMEEALILDNKYTEH 301
Query: 567 STVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMMFKHFDKEKTGRLDH 388
STVG+AQ WDQLDQL MRMQHNLEQQIQARN +GV+EEAL+EFSMMFKHFDK+K+GRL+H
Sbjct: 302 STVGLAQQWDQLDQLGMRMQHNLEQQIQARNTTGVTEEALKEFSMMFKHFDKDKSGRLNH 361
Query: 387 QQFKSCLRALGYDLPMVDEGQPEPEFQRILDIVDPNRDGYVTLQEYMAFMISKETENIQS 208
Q+FKSCLR+LGYDLPMV+EG+P+PEF+ ILD VDPNRDG+V+LQEYMAFMIS+ETEN++S
Sbjct: 362 QEFKSCLRSLGYDLPMVEEGEPDPEFEAILDTVDPNRDGHVSLQEYMAFMISRETENVKS 421
Query: 207 SEEIEMAFRALSKEFRPYVTAEELYANLTPEQAEFCIRRMKPYMDAISGRSIQGGLDYEQ 28
SEEIE AFRALS E +PYVT EELY NLT EQA++C+ MKPY+D GR + DY +
Sbjct: 422 SEEIESAFRALSSEGKPYVTKEELYQNLTREQADYCVSHMKPYVDG-KGRELPTAFDYVE 480
Query: 27 FVHALF 10
F +LF
Sbjct: 481 FTRSLF 486
Score = 77.4 bits (189), Expect = 5e-12
Identities = 72/352 (20%), Positives = 148/352 (41%), Gaps = 17/352 (4%)
Frame = -1
Query: 1758 EAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQR-VADLINKGDTLIHNGN 1582
E+W+ EK+ L +D++G +++ VQ LL K +TF L+ +Q +A++ D L+ +
Sbjct: 5 ESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKH 64
Query: 1581 HHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSA--------YLQFMWKCDVVESWIA 1426
+ I+ R L R ++ + + R KL + + +L F K SW
Sbjct: 65 IQSKAIEARHASLMKRWTQLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFE 124
Query: 1425 EKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPA 1246
E+ + L ++ L +AF + L++ + + ++ EL Q+ S +P
Sbjct: 125 NAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQAD-FNQLAELDRQIKSFRVASNPY 183
Query: 1245 IEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEED 1066
+ + W+NL + R + ++L FA+ A+ F+ W +
Sbjct: 184 TWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRTY 243
Query: 1065 LTD----PVRCNSLE-EIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYT 901
L D +LE ++ A + H E + + ++++DL ++ + N YT
Sbjct: 244 LLDGSCMVEESGTLESQLEATKRKHQE----IRAMRSQLKKIEDLGAAMEEALILDNKYT 299
Query: 900 WFTMDALEDTWRNLQRIIKEREQELAREHQRQEE---NDKLRREFAKLANAF 754
+ L W L ++ + L ++ Q + ++ +EF+ + F
Sbjct: 300 EHSTVGLAQQWDQLDQLGMRMQHNLEQQIQARNTTGVTEEALKEFSMMFKHF 351
Score = 73.6 bits (179), Expect = 7e-11
Identities = 85/356 (23%), Positives = 151/356 (41%), Gaps = 43/356 (12%)
Frame = -1
Query: 3681 DETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDK-IKSLDEKANRLRQ 3505
D WI EK+++L ++D+GRDL SVQ L K E + L A + I ++ ++L
Sbjct: 2 DVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLA 61
Query: 3504 SHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDY--------RDLMQ 3349
+ ++ I L ++W +L + + RK+KLL++ + R + D
Sbjct: 62 AKHIQSKAIEARHASLMKRWTQLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASAFNS 121
Query: 3348 WIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQL----LNSH 3181
W + + ++ N + +AL E H +R+ + S A F + Q+ + S+
Sbjct: 122 WFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASN 181
Query: 3180 HYAAGDIENRLQGVNEARKGLEDAWVARRNIL-DQCLELQLFYRDCEQAD---------- 3034
Y +E LE+ W + I+ ++ LELQ R E+ D
Sbjct: 182 PYTWFTME-----------ALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHA 230
Query: 3033 ----TWMSAREAFL----AQEDPSG---DNVESLIKKHEDFDKAINTQEEKIKGL-KLFA 2890
W+ +L + SG +E+ +KH++ +A+ +Q +KI+ L
Sbjct: 231 NAFHQWIQETRTYLLDGSCMVEESGTLESQLEATKRKHQEI-RAMRSQLKKIEDLGAAME 289
Query: 2889 ESLIKNNHYDSPAVT------RKRDQILDRWNGLKEALIQKRFKLG-ESQTLQQFS 2743
E+LI +N Y + + DQ+ R E IQ R G + L++FS
Sbjct: 290 EALILDNKYTEHSTVGLAQQWDQLDQLGMRMQHNLEQQIQARNTTGVTEEALKEFS 345
Score = 67.8 bits (164), Expect = 4e-09
Identities = 78/323 (24%), Positives = 129/323 (39%), Gaps = 31/323 (9%)
Frame = -1
Query: 5166 VEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNA-HNDRVDGIKQLAQQFQEEE 4990
VE+W+ E E + ++DYG+DL SVQ L K ++ A + + I L Q +
Sbjct: 4 VESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAK 63
Query: 4989 HFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDEL----------- 4843
H + I + +L +R+ L RK+KL E+ FR +ED
Sbjct: 64 HIQSKAIEARHASLMKRWTQLLANSATRKKKLLEAQSH---FRKVEDLFLTFAKKASAFN 120
Query: 4842 AWIREKEQVAGSTNRGRDLIGVQNL----------IKKQQALIAEIANHDSQIESVSSAA 4693
+W E+ R L ++ L + QA ++A D QI+S A+
Sbjct: 121 SWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVAS 180
Query: 4692 NDMIQQGHFLAPEIRDKLAQLRDNWRILKS---------KAEKRRTDLDDSLQAHQYLSD 4540
N P + L + WR L+ + E+RR + +D L+ ++
Sbjct: 181 N----------PYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLR-QEFAQH 229
Query: 4539 ANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKY 4360
AN W+ E + Y D ++++ L S LEA K +++R SQ K
Sbjct: 230 ANAFHQWIQE------TRTYLLD---GSCMVEESGTLESQLEATKRKHQEIRAMRSQLKK 280
Query: 4359 QEQPMGQLGRDCVLALYDYQEKS 4291
E +G + ++ Y E S
Sbjct: 281 IED-LGAAMEEALILDNKYTEHS 302
Score = 64.3 bits (155), Expect = 4e-08
Identities = 63/285 (22%), Positives = 116/285 (40%), Gaps = 22/285 (7%)
Frame = -1
Query: 6444 ADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGK-MLQLEKEAHKLA 6268
AD +WIGEK+ +L +DDYGRDL++VQ L K E + L A + + + + +L
Sbjct: 1 ADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLL 60
Query: 6267 ETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADY--------RDLI 6112
+++AI ++ W L + RK L + R + D
Sbjct: 61 AAKHIQSKAIEARHASLMKRWTQLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASAFN 120
Query: 6111 SWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPE 5932
SW + + + + +AL E+H + + + FNQ A +++ +
Sbjct: 121 SWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVAS 180
Query: 5931 SPEVQEKLEKLDHE--------KSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQ 5776
+P +E L+ K L L +E+R E Q F + W+ +
Sbjct: 181 NPYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQET 240
Query: 5775 EAFLAN-----TDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINAL 5656
+L + + G +E +KH++ +++ +Q +KI L
Sbjct: 241 RTYLLDGSCMVEESGTLESQLEATKRKHQEI-RAMRSQLKKIEDL 284
Score = 62.0 bits (149), Expect = 2e-07
Identities = 71/318 (22%), Positives = 130/318 (40%), Gaps = 30/318 (9%)
Frame = -1
Query: 2406 LEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVA-HQDRVGEMNEQADSLLEND 2230
+E W+GE E L+++DYG+DL+SV+ LL K +A + A Q+ + + D LL
Sbjct: 4 VESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAK 63
Query: 2229 QFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDD-----------EE 2083
Q + I R + R+ + + R+ KL L FR ++D
Sbjct: 64 HIQSKAIEARHASLMKRWTQLLANSATRKKKL---LEAQSHFRKVEDLFLTFAKKASAFN 120
Query: 2082 SWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEA 1903
SW + + ++ L ++ LR H + L+S + + + EL R
Sbjct: 121 SWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQL----AELDRQIKSF 176
Query: 1902 GVGEDQIK-KRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEA--------W 1750
V + ME LE++W ++ + R L + + Q + +E A W
Sbjct: 177 RVASNPYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQW 236
Query: 1749 MNEKQQIL--GS---DNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNG 1585
+ E + L GS + G + ++ +KH + + +++ DL + +
Sbjct: 237 IQETRTYLLDGSCMVEESGTLESQLEATKRKHQEIRA-MRSQLKKIEDLGAAMEEALILD 295
Query: 1584 NHHAPH----IKQRCDQL 1543
N + H + Q+ DQL
Sbjct: 296 NKYTEHSTVGLAQQWDQL 313
Score = 53.9 bits (128), Expect = 6e-05
Identities = 41/159 (25%), Positives = 69/159 (42%), Gaps = 10/159 (6%)
Frame = -1
Query: 2094 DDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQ--VSLVKLKGEELL 1921
D ESWI EK+ + +DDYGRDL VQ L K D L + + + ++ LK + L
Sbjct: 2 DVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLL- 60
Query: 1920 RSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEA--------FQAFLGDVE 1765
A + I+ R L + W Q+ + R ++L E+++ F F
Sbjct: 61 ---AAKHIQSKAIEARHASLMKRWTQLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKAS 117
Query: 1764 EEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDL 1648
+W ++ L ++ ++ L + HD F+ L
Sbjct: 118 AFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSL 156
Score = 48.9 bits (115), Expect = 0.002
Identities = 42/165 (25%), Positives = 66/165 (39%), Gaps = 9/165 (5%)
Frame = -1
Query: 6759 DEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYR-INEINQAADKLVE 6583
D + WI EKE + +D G DL V+ L K + F L Q I I D+L+
Sbjct: 2 DVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLA 61
Query: 6582 EGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQR--------FNRDADETLA 6427
H + I + + W +L +ATRK+ L A R F + A +
Sbjct: 62 AKHIQSKAIEARHASLMKRWTQLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASAFNS 121
Query: 6426 WIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQL 6292
W + L+ L ++AL+ H+ L++ + QL
Sbjct: 122 WFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQL 166
Score = 45.8 bits (107), Expect = 0.015
Identities = 74/354 (20%), Positives = 144/354 (39%), Gaps = 29/354 (8%)
Frame = -1
Query: 2736 ADEIENWMTEKFQIAQEENY-RDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIE 2560
AD +E+W+ EK + ++Y RD +++Q KQ+ F+A L A A I A + +
Sbjct: 1 ADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLL 60
Query: 2559 NAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQ--------KSFMAAVKDL 2404
AK + A+ AR +L +W L+ + + +L EA +F
Sbjct: 61 AAKHIQSK-AIEARHASLMKRWTQLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASAF 119
Query: 2403 EFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQ---DRVGEMNEQADSL--- 2242
W E L L ++ L + H + + + Q +++ E++ Q S
Sbjct: 120 NSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVA 179
Query: 2241 -----------LENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSK--ALNVHQFFR 2101
LE Q+I + R+L + ++ + DKL + A + + F +
Sbjct: 180 SNPYTWFTMEALEETWRNLQKIIKERELELQK----EQRRQEENDKLRQEFAQHANAFHQ 235
Query: 2100 DIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELL 1921
I + +++ + +V ++ G ++ +RKH+ E+ + Q+ K E+L
Sbjct: 236 WIQETRTYLLDGSCMV--EESGTLESQLEATKRKHQ----EIRAMRSQLK----KIEDLG 285
Query: 1920 RSAAEAGVGEDQIKKRME-DLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEE 1762
+ EA + +++ + L Q W Q+ L L++ + G EE
Sbjct: 286 AAMEEALILDNKYTEHSTVGLAQQWDQLDQLGMRMQHNLEQQIQARNTTGVTEE 339
Score = 44.3 bits (103), Expect = 0.045
Identities = 65/345 (18%), Positives = 135/345 (38%), Gaps = 25/345 (7%)
Frame = -1
Query: 5487 DEMVSWITEKLSTARDDSY-LDPTNIRGKLQKHINFEQELKA-NENRLDDIRSTGEQIID 5314
D + SWI EK ++ + D Y D ++++ L K F+ L+A + + +I + +Q++
Sbjct: 2 DVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLA 61
Query: 5313 SGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDV---------- 5164
+ H + I R + W +L+ + + KL EA Q R +ED+
Sbjct: 62 AKHIQSKAIEARHASLMKRWTQLLANSATRKKKLLEA---QSHFRKVEDLFLTFAKKASA 118
Query: 5163 -EAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEH 4987
+W E + L ++ L++ S ++ + + +L +Q +
Sbjct: 119 FNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRV 178
Query: 4986 FNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELA--------WIR 4831
+ P E L++ + L+ +++R+ +L + + + + E A WI+
Sbjct: 179 ASNPYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQ 238
Query: 4830 EKEQ--VAGS--TNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFL 4663
E + GS L K++ I + + +IE + +A + + +
Sbjct: 239 ETRTYLLDGSCMVEESGTLESQLEATKRKHQEIRAMRSQLKKIEDLGAAMEEALILDNKY 298
Query: 4662 APEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEA 4528
LAQ W L + + +L+ +QA EA
Sbjct: 299 TEHSTVGLAQ---QWDQLDQLGMRMQHNLEQQIQARNTTGVTEEA 340
Score = 38.5 bits (88), Expect = 2.5
Identities = 69/387 (17%), Positives = 141/387 (35%), Gaps = 19/387 (4%)
Frame = -1
Query: 4539 ANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKY 4360
A+ ++W+ EKE + + DYG+D S + LL K + L+AF
Sbjct: 1 ADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAF---------------- 44
Query: 4359 QEQPMGQLG--RDCVLALYDYQEKS--PREVSMKKGDVLTLLNASNRDWWKVEVNDRQGF 4192
Q++ + + +D +LA Q K+ R S+ K L N++ R +E
Sbjct: 45 QQEGIANITALKDQLLAAKHIQSKAIEARHASLMKRWTQLLANSATRKKKLLE------- 97
Query: 4191 VPAAYVKRIEPGTAQQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLL 4012
AQ H + ++ED +
Sbjct: 98 -------------AQSHFR-----------KVEDLF--------------------LTFA 113
Query: 4011 REANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATAL 3832
++A+ W ++ E LE+++ L++ D F+ L + + ++ ++ +
Sbjct: 114 KKASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQI 173
Query: 3831 TSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGS---------------AHEVQR 3697
S + + +E L WR L +L A
Sbjct: 174 KSF-RVASNPYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANA 232
Query: 3696 FHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKAN 3517
FH+ + ETR ++ D + E+ G ++A +RKH+ ++ A+ ++K +++
Sbjct: 233 FHQWIQETRTYL--LDGSCMVEESGTLESQLEATKRKHQ----EIRAMRSQLKKIEDLGA 286
Query: 3516 RLRQSHPEAAEQIYDLQRELNEQWNRL 3436
+ ++ + L +QW++L
Sbjct: 287 AMEEALILDNKYTEHSTVGLAQQWDQL 313
>gi|39592126|emb|CAE75346.1| Hypothetical protein CBG23326
[Caenorhabditis briggsae]
Length = 4061
Score = 662 bits (1709), Expect = 0.0
Identities = 525/2281 (23%), Positives = 1021/2281 (44%), Gaps = 58/2281 (2%)
Frame = -1
Query: 7191 IHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENFRD 7012
+ ++ Q ++ + +D + + L++ Q F R+++ ++ + +N D
Sbjct: 1208 VEEQLQALVSEMAALRDLYRRRDTILKQQLDLQLFNRESERIDAATKGHEAFLEFDNLGD 1267
Query: 7011 P-SNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXX 6835
+++ +++H EA++ A + +T + MI+ H S +I++R ++ A
Sbjct: 1268 SVESVENLLKRHRDLEAKLDAQEARLEAFSRTADDMIKAQHADSAYIEQRRRDVLARREA 1327
Query: 6834 XXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTA-EDMGMDLEHVEILQRKFD 6658
+ +L+ +L+ R+ DE++ W+ EK V + +D + + K +
Sbjct: 1328 VRRAAAQRKKQLEASLEYQEMRREADEVMGWMHEKAKLVASGDDAALAPSAIPHRLLKHE 1387
Query: 6657 DFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLF 6478
F E+ ++ RI +IN+ D LV + H E + K VN W L + + L
Sbjct: 1388 AFEAEIIANESRIQQINREGDNLVGKNHYESPNVEKVVRQVNAQWGDLKKQVYNKGQRLR 1447
Query: 6477 GAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKML 6298
A + +R ++ A + E + AL+S D G DL +V+ L +KH E+++ K+
Sbjct: 1448 QAADQKGLDRILEDAHAKLDEMESALNSKDQGLDLRSVKDLLQKHTVLEQEMGLYGNKLA 1507
Query: 6297 QLEKEAHKLA-ETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYR 6121
+E K+A E H D A+ IH D + A+K AQ RK L+ S H+ + D
Sbjct: 1508 DIENRGKKMAVEGHYD-ADKIHMTVGDLLKRYAAMKGPAQRRKGDLDESRLWHQLVFDVD 1566
Query: 6120 DLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMG 5941
+ WI + K + + + + + A +++ ++ + E++ ++ KLV+
Sbjct: 1567 CELQWIAEKKPIASSQDCGRTLTEALNMVKKQEQLEAEVNQHGGQIDKVLGQASKLVKRH 1626
Query: 5940 IPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLA 5761
P S +++ K +L+ S L L RR + + + Q + D + E+WMN++ LA
Sbjct: 1627 HPASSQIKAKSGELESAWSELRRLLRSRRAIVDWGVKEQQYLFDAAEVESWMNEKRNALA 1686
Query: 5760 NTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXX 5581
+ D G+ D+ L+ KH + + + + LD ++L+Q D +
Sbjct: 1687 SEDYGNDEDAARKLLAKHRALCEDMTTYRQWLEKLDVKCSELVQSDRPHVDRFQKRQDEL 1746
Query: 5580 XXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGKL 5401
R NAL+++ + R+ ++ WI E+L TA + + + +L
Sbjct: 1747 VHEFDSLSKLAEDRRNALEDAVCLYEYMRESADLEQWIGEQLQTALCEDFAEDYEHLKEL 1806
Query: 5400 Q-KHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKK 5224
Q K F+Q +K R + I+ A + + ++ + WN L + +
Sbjct: 1807 QSKFDEFKQSVKTGSERFTSCETAANTILRRNPPFARDVVKKQEKLRSAWNLLCEYIETR 1866
Query: 5223 GAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAH 5044
AKL A +F+R++++ E W+++ + D G+D+ V +L ++ ++ + +
Sbjct: 1867 TAKLAVAEELHRFHRDVDEFEQWMADKMANMP-RDLGRDVKHVHSLWQQHEALDKETHNA 1925
Query: 5043 NDRVDGIKQLAQQFQEE-EHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQL 4867
R+ + + A++ ++ NA I +Q+ L + + LR+ + RK L + +
Sbjct: 1926 QPRLTKLVEEAERLKKAYPGGNAEQIGGRQQTLVEEWEELRNATDDRKDMLRAAFDLHTF 1985
Query: 4866 FRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAAND 4687
+ D LAW S + DL + L + L E+ + + + S
Sbjct: 1986 NGKVRDLLAWTDLTISDIQSDLQINDLQQAEWLQTEHSRLSHEMDAREPEFTRLVSDGEK 2045
Query: 4686 MIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEK 4507
M+ H+ EI++K L+ L+S+ R L ++Q H + +A + A + K
Sbjct: 2046 MVNAQHYATEEIKNKTRLLKTALERLRSEWTLRNGYLSQAVQWHAFQREAKQIIASIGSK 2105
Query: 4506 EPIVGSTDYG---KDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQP---- 4348
+ S G D +S + L LS L+ T++ + + ++ E
Sbjct: 2106 RTTLRSLAVGGSVADVESQKKRLDTFEKALSTLDERTATLDHTANELVKSRHMESKNIAM 2165
Query: 4347 -MGQLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNA--SNRDWW---------KVEVND 4204
++ + L D + R V +K L + + + W K
Sbjct: 2166 WQSKVHEELKLLREDIEA---RHVMLKDAFALASFGSDVAQIEAWIDEKTNGIRKARDQS 2222
Query: 4203 RQGFVPAAYVKRIEPGTAQQ--------------HAQQQVNS------IGGKQSEIEDKY 4084
+ +KR++ A + H QQ+ S IG +E+ K+
Sbjct: 2223 SESISIEEKMKRLQTHQALEAEVAANKTIVDQILHRGQQLKSLHRNSKIGDTCNELNVKW 2282
Query: 4083 QRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKF 3904
+L + + R LEEA + + ++ WI +E + + ++G D+E +L ++
Sbjct: 2283 SQLAGACDDQSRALEEARDLLRFKQLVENVLTWINEKEVLVSTADMGRDMEHCRMLLERL 2342
Query: 3903 DDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQ 3724
D + D +E L E+N++ L G+T +++++ + LN +WR L +
Sbjct: 2343 DGTRSDSTVDEQTLDEINRLGEKLVKQGRTSRD-QVQKEQQRLNEKWRLLLGQLSHYRTE 2401
Query: 3723 LGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDK 3544
L +A EV F+RDV++T + I EK A+ S+DFG+D SV+ L RK +ERD++A+ K
Sbjct: 2402 LVAAMEVHTFNRDVEDTDERIHEKIAAMKSDDFGKDFASVELLVRKQSALERDMSAIHQK 2461
Query: 3543 IKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDY 3364
+ S D+ A ++ + P E I D ++L E W +L+ A R +KL S+ ++L D
Sbjct: 2462 LISHDKDAQKILEKRPPLKESILDSLKKLEESWKKLSEAAELRNDKLNRSFKLYKYLDDV 2521
Query: 3363 RDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNS 3184
+ QW + ++S + D +GA LLE+H E + EID RA + + G L
Sbjct: 2522 KKTEQWANQVRNKMTSHQTPKDSSGARKLLEQHHERKAEIDGRADELRQLHEEGQALNQE 2581
Query: 3183 HHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFL 3004
+++ + V + L W + + L + LE L+ + Q + W++ +E +
Sbjct: 2582 QPEHKAEVQRAHKRVQNSEHQLRQTWESEKGTLQKLLEWMLWCDEAVQCEQWLADKENQV 2641
Query: 3003 AQED--PSGDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIK-NNHYDSPAVTRKRD 2833
++ + + D VE LIK H F++ + Q EKI L A++L+ N+Y + +TRK D
Sbjct: 2642 SRGELGDTSDAVEMLIKGHSAFEETVRKQSEKIDVLVKNADALVSGGNNYRADIITRK-D 2700
Query: 2832 QILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNIQQ 2653
++ R + L +++ +++ L +S+ +F R E+ W+T K Q+A +E++ D TN++
Sbjct: 2701 EVTARHDLLLKSMSKRKDMLEDSKRYHEFIRHCGELIIWITAKLQLAYDESFLDHTNLRS 2760
Query: 2652 KHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTT 2473
K QK AF++EL N R++ + + G L+ + + V A+L L WD L +
Sbjct: 2761 KLQKHMAFDSELVENEKRLSNVERQGEELVADNHFMSEQ--VKAQLVELRSGWDELRTKS 2818
Query: 2472 TEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADI 2293
K+ RL+EA + S V+DLE WL +VE L SED+G+D+ S E L+KK L+ +I
Sbjct: 2819 ALKTQRLREAFELHSLQRKVEDLEKWLDKVEGELASEDHGRDMLSTELLIKKLDTLQTEI 2878
Query: 2292 VAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVH 2113
D V EM ++A L ++ + + RY G+ + RR+ L A
Sbjct: 2879 AGRSDAVVEMMKKARELRVQGSAAADDCLKQAEQVEARYSGLDEPVQIRRENLVDAQAFF 2938
Query: 2112 QFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKG 1933
++ + +++ W+ +K L SS + G L +L++KH ++ EL + + + + +G
Sbjct: 2939 EWVKAAEEDLEWLSDKMPLASSGESGDSLQSALSLQKKHAALEKELETRQSAMDDTEKRG 2998
Query: 1932 EELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEA 1753
++++R + I+K ++ L + +++ G R L E+ + + E E
Sbjct: 2999 KDMIR---QRHFASGHIQKILDRLSTAMLTLKESCGLRRDLLQEAIDAHEYYTEETEAEQ 3055
Query: 1752 WMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHA 1573
W+ E+ + S G + AG + L++ ++EL K + L + D L+ +H A
Sbjct: 3056 WLREQMPLAMSQEMGRDQAGAESHLRRLTVLDKEVELFKNEIDRLKKRADGLLAREHHDA 3115
Query: 1572 PHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDF 1393
I + +L A ++ R ++ D S Y +F+ + D + W+ EKE+ +ED+
Sbjct: 3116 MSIAAKQRKLEALFGDLCRECARRRTQIVDASKYHKFVRQADDLSDWLREKERTASAEDY 3175
Query: 1392 GRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQR 1213
G+DL Q ++ + E+ L A E + + ++ L+ S H +I + +V +
Sbjct: 3176 GQDLEDCQQIIEQFESTVREL-AAAGERVALVQRSQEDLLRSGHPYGASITAKGADVQRL 3234
Query: 1212 WQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAE--------EDLTD 1057
W ++ + R+ F ++A +W ++ E EDL+
Sbjct: 3235 WTHVNEVANERKQALNGARQVH--------RFDQEADQTLNWLQDKEATGVAMEQEDLSR 3286
Query: 1056 PVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQL-QDLDRRIKSFNVGPNPYTWFTMDAL 880
L ++A H EF + + E+ +L + +R SF P T ++
Sbjct: 3287 A----DLASVKAQLQRHDEFMHGMKAVEKQVAELCHEAERLWNSF-----PDTRHHLEVR 3337
Query: 879 E-DTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEMMEAGGT 703
D L+ I++ ++ L R Q + + + T T +++ +
Sbjct: 3338 RLDMEEQLKDILEAAKKHLERLRHMQSLQSYFQEYREMMQWMKNMQTTMTSEQLPRDVAS 3397
Query: 702 LEEQLDAVERKAKEIKANKGQLRQIEEKG-AMLERNLILDNRYTEHSTVGIAQAWDQLDQ 526
E + + E++ K + +G M++ + +L E V + ++W+ L +
Sbjct: 3398 CESLVRRHDEYNLEMQGRKPFVDDFARQGRRMIQSSHVLSQEIQEKVEV-LEKSWEMLCE 3456
Query: 525 L 523
+
Sbjct: 3457 I 3457
Score = 631 bits (1627), Expect = e-179
Identities = 520/2136 (24%), Positives = 951/2136 (44%), Gaps = 74/2136 (3%)
Frame = -1
Query: 6801 LQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELG-NHQY 6625
L +KLL F R+CD+ W KE V+ D EHV +RKFD ++ N
Sbjct: 928 LSDNIKLLRFYRECDDFERW---KEIEVSLADEPSP-EHVTAFRRKFDKLEADMKTNGGT 983
Query: 6624 RINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRD 6445
++ IN A+ L+ EGH + QI ++ +N W L L R L +V F+
Sbjct: 984 QLKHINDIANDLISEGHGQSRQIENRQHKINAMWENLERLRKQRAVRLEATERVADFDTT 1043
Query: 6444 ADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAE 6265
+ W+ K + R+ N+V++LQ ERDL LE K+ LEK A + +
Sbjct: 1044 CESAREWMLGK-----FEQLDRNPNDVKSLQN----LERDLKPLEDKIAALEKLAAAVKK 1094
Query: 6264 THPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAV 6085
HP+ A AI +K + + L +AQ + E+S F + RD++SWI +
Sbjct: 1095 DHPEEAAAIERKIAELRTLHADLLRRAQEKMLLAEQSQGKEMFESALRDMMSWIEKTRKG 1154
Query: 6084 IGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLE 5905
+ D DVA AE LL+ H E +I + G++L+E P P+V+E+L+
Sbjct: 1155 MMEDVHPVDVAEAEELLKKHYELGEQIKDKKYEVEYCQELGRRLLERS-PRMPKVEEQLQ 1213
Query: 5904 KLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVE 5725
L E ++L L+ R + +Q +DLQLF R++E+ + EAFL +LGDS++SVE
Sbjct: 1214 ALVSEMAALRDLYRRRDTILKQQLDLQLFNRESERIDAATKGHEAFLEFDNLGDSVESVE 1273
Query: 5724 HLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXX 5545
+L+K+H D E L AQE ++ A A +I+ QH + + +
Sbjct: 1274 NLLKRHRDLEAKLDAQEARLEAFSRTADDMIKAQHADSAYIEQRRRDVLARREAVRRAAA 1333
Query: 5544 XRGNALKESYKRQTFDRDCDEMVSWITEK--LSTARDDSYLDPTNIRGKLQKHINFEQEL 5371
R L+ S + Q R+ DE++ W+ EK L + DD+ L P+ I +L KH FE E+
Sbjct: 1334 QRKKQLEASLEYQEMRREADEVMGWMHEKAKLVASGDDAALAPSAIPHRLLKHEAFEAEI 1393
Query: 5370 KANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQ 5191
ANE+R+ I G+ ++ H+ + ++ +RQVN W +L KG +LR+A +++
Sbjct: 1394 IANESRIQQINREGDNLVGKNHYESPNVEKVVRQVNAQWGDLKKQVYNKGQRLRQAADQK 1453
Query: 5190 QFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLA 5011
+R +ED A L E+E + S+D G DL SV++L +K ++E + + +++ I+
Sbjct: 1454 GLDRILEDAHAKLDEMESALNSKDQGLDLRSVKDLLQKHTVLEQEMGLYGNKLADIENRG 1513
Query: 5010 QQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIR 4831
++ E H++A I +L +RY A++ P ++RK L ES +QL D++ EL WI
Sbjct: 1514 KKMAVEGHYDADKIHMTVGDLLKRYAAMKGPAQRRKGDLDESRLWHQLVFDVDCELQWIA 1573
Query: 4830 EKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEI 4651
EK+ +A S + GR L N++KKQ+ L AE+ H QI+ V A+ ++++ H + +I
Sbjct: 1574 EKKPIASSQDCGRTLTEALNMVKKQEQLEAEVNQHGGQIDKVLGQASKLVKRHHPASSQI 1633
Query: 4650 RDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKD 4471
+ K +L W L+ RR +D ++ QYL DA E ++WM+EK + S DYG D
Sbjct: 1634 KAKSGELESAWSELRRLLRSRRAIVDWGVKEQQYLFDAAEVESWMNEKRNALASEDYGND 1693
Query: 4470 EDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQP------------------M 4345
ED+A LL KHRAL D+ ++ +E L + S+ ++P +
Sbjct: 1694 EDAARKLLAKHRALCEDMTTYRQWLEKLDVKCSELVQSDRPHVDRFQKRQDELVHEFDSL 1753
Query: 4344 GQLGRD------CVLALYDYQEKSPREVSMKKGDVL--TLLNASNRDWWKV-EVNDRQGF 4192
+L D + LY+Y +S ++ G+ L L D+ + E+ +
Sbjct: 1754 SKLAEDRRNALEDAVCLYEYMRES-ADLEQWIGEQLQTALCEDFAEDYEHLKELQSKFDE 1812
Query: 4191 VPAAYVKRIEPGTAQQHAQQQV--------NSIGGKQSEIEDKYQRLMMLGETRKRKLEE 4036
+ E T+ + A + + KQ ++ + L ETR KL
Sbjct: 1813 FKQSVKTGSERFTSCETAANTILRRNPPFARDVVKKQEKLRSAWNLLCEYIETRTAKLAV 1872
Query: 4035 ACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQE 3856
A + ++ R+ ++ +W+ + A +++G D++ V L ++ + + + RL +
Sbjct: 1873 AEELHRFHRDVDEFEQWMADKMA-NMPRDLGRDVKHVHSLWQQHEALDKETHNAQPRLTK 1931
Query: 3855 MNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDE 3676
+ + A L A +I + + L W L L +A ++ F+ V +
Sbjct: 1932 LVEEAERLKKAYPGGNAEQIGGRQQTLVEEWEELRNATDDRKDMLRAAFDLHTFNGKVRD 1991
Query: 3675 TRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHP 3496
W + S+ DL+ + LQ +H + ++ A + L ++ +
Sbjct: 1992 LLAWTDLTISDIQSDLQINDLQQAEWLQTEHSRLSHEMDAREPEFTRLVSDGEKMVNAQH 2051
Query: 3495 EAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSS 3316
A E+I + R L RL S+ R L + + F + + ++ I S + S
Sbjct: 2052 YATEEIKNKTRLLKTALERLRSEWTLRNGYLSQAVQWHAFQREAKQIIASIGSKRTTLRS 2111
Query: 3315 QELANDVTGAEA---LLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQ 3145
+ V E+ L+ ++ + +D R AT D N+L+ S H + +I
Sbjct: 2112 LAVGGSVADVESQKKRLDTFEKALSTLDERTAT---LDHTANELVKSRHMESKNIAMWQS 2168
Query: 3144 GVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAR-EAFLAQEDPSGDNVE- 2971
V+E K L + AR +L L F D Q + W+ + D S +++
Sbjct: 2169 KVHEELKLLREDIEARHVMLKDAFALASFGSDVAQIEAWIDEKTNGIRKARDQSSESISI 2228
Query: 2970 ----SLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLK 2803
++ H+ + + + + + L +K+ H +S + +++ +W+ L
Sbjct: 2229 EEKMKRLQTHQALEAEVAANKTIVDQI-LHRGQQLKSLHRNS-KIGDTCNELNVKWSQLA 2286
Query: 2802 EALIQKRFKLGESQTLQQFSRDADEIENWMTEK-FQIAQEENYRDPTNIQQKHQKQQAFE 2626
A + L E++ L +F + + + W+ EK ++ + RD + + ++
Sbjct: 2287 GACDDQSRALEEARDLLRFKQLVENVLTWINEKEVLVSTADMGRDMEHCRMLLERLDGTR 2346
Query: 2625 AELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKE 2446
++ + + I + G L++ + + V + LN++W LL+ + L
Sbjct: 2347 SDSTVDEQTLDEINRLGEKLVKQGRTSRDQ--VQKEQQRLNEKWRLLLGQLSHYRTELVA 2404
Query: 2445 ANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGE 2266
A + +F V+D + + E ++S+D+GKD ASVE L++K S LE D+ A ++
Sbjct: 2405 AMEVHTFNRDVEDTDERIHEKIAAMKSDDFGKDFASVELLVRKQSALERDMSAIHQKLIS 2464
Query: 2265 MNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDE 2086
++ A +LE + I + K + + + + + A R DKL+++ ++++ D+
Sbjct: 2465 HDKDAQKILEKRPPLKESILDSLKKLEESWKKLSEAAELRNDKLNRSFKLYKYLDDVKKT 2524
Query: 2085 ESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAE 1906
E W + + ++S +D G + L +H E+ ++ + +G+ L + E
Sbjct: 2525 EQWANQVRNKMTSHQTPKDSSGARKLLEQHHERKAEIDGRADELRQLHEEGQALNQEQPE 2584
Query: 1905 AGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQIL 1726
+ KR+++ E Q+R + L + + + + + E W+ +K+ +
Sbjct: 2585 HKAEVQRAHKRVQNSEH---QLRQTWESEKGTLQKLLEWMLWCDEAVQCEQWLADKENQV 2641
Query: 1725 GSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQ 1546
G+ V+ L+K H F+ + +++ L+ D L+ GN++ I R D+
Sbjct: 2642 SRGELGDTSDAVEMLIKGHSAFEETVRKQSEKIDVLVKNADALVSGGNNYRADIITRKDE 2701
Query: 1545 LRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQI 1366
+ AR + R L D+ Y +F+ C + WI K Q E F D ++++
Sbjct: 2702 VTARHDLLLKSMSKRKDMLEDSKRYHEFIRHCGELIIWITAKLQLAYDESF-LDHTNLRS 2760
Query: 1365 LLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSE 1186
L K AFD+ L E + + + ++LV+ H S ++ + + W L S
Sbjct: 2761 KLQKHMAFDSELVENE-KRLSNVERQGEELVADNHFMSEQVKAQLVELRSGWDELRTKSA 2819
Query: 1185 ARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAH 1006
+ EL+ + +K W + E +L + H
Sbjct: 2820 LKTQRLREAF-------ELH-SLQRKVEDLEKWLDKVEGELAS--------------EDH 2857
Query: 1005 GEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRI-------- 850
G R + S E ++L L I DA+ + + + +
Sbjct: 2858 G---RDMLSTELLIKKLDTLQTEIAG-----------RSDAVVEMMKKARELRVQGSAAA 2903
Query: 849 ---IKEREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEMM------------E 715
+K+ EQ AR + +E ++RRE A AF W+ +++ E
Sbjct: 2904 DDCLKQAEQVEAR-YSGLDEPVQIRRENLVDAQAFFEWVKAAEEDLEWLSDKMPLASSGE 2962
Query: 714 AGGTLEEQLDAVERKA---KEIKANKGQLRQIEEKG 616
+G +L+ L ++ A KE++ + + E++G
Sbjct: 2963 SGDSLQSALSLQKKHAALEKELETRQSAMDDTEKRG 2998
Score = 559 bits (1441), Expect = e-157
Identities = 418/1598 (26%), Positives = 727/1598 (45%), Gaps = 33/1598 (2%)
Frame = -1
Query: 5478 VSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFA 5299
V + E++ R S ++ T L+K ++ A E+R + + ++ +
Sbjct: 436 VQVVLEEMEHGRSASQVEKT-----LKKQQAISTDILAREDRFKMLTAMCNELCTEKYHE 490
Query: 5298 ADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASED 5119
++ I R++ + W +L+ ++ L + R+I+ + L LE V + D
Sbjct: 491 SEKIRGMEREIIDRWTQLLALLEQRKRALMSLNDLMSLLRDIDTLSNELYSLEPAVRNRD 550
Query: 5118 YGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQR 4939
GK L+ V++L K L+++ NAH + + Q A + + V+ RK + + +
Sbjct: 551 VGKHLIGVEDLLGKHDLVDAQINAHGSLLSKLSQAANNYIRHKEEQFDVLQRKLDEVTSQ 610
Query: 4938 YNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKK 4759
YN L + R+ L + Q +D E+E+AW+ EKE++ + D+ V
Sbjct: 611 YNTLVELCRSRRLALERARSLFQFIQDHEEEMAWLAEKEKLCTTALNSGDISAVPQTTLL 670
Query: 4758 QQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTD 4579
+ + E+ H ++ + + + ++Q G +I+ +L Q+ W L+ +
Sbjct: 671 YKNVEMEMQTHWARSKGMIAGGERLVQSGQS-KEDIQRRLTQMNQGWERLRVAVDALGNW 729
Query: 4578 LDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGT 4399
L ++ A QY D NEA++W+ EK P+V S D G+DE +AE+LL++H L ++ A+K
Sbjct: 730 LSEARHAQQYFQDVNEAESWIREKMPLVKSDDLGRDEGAAESLLQRHARLEEEIRAYKND 789
Query: 4398 I---EDLRKQASQCKYQEQPMGQLGRDC-------VLALYDYQEKSPREVSMKKGDVLTL 4249
I E+++ Q + + Q ++ + Y Y+ R + KG+VL L
Sbjct: 790 ITRLEEMQSQLANSAFHTATTSQSVQETEEVTVPQIEMAYKYEGNGMR---VAKGEVLAL 846
Query: 4248 LNASNRDWWKVEVND-RQGFVPAAYVKRI--EPGTAQQHAQQQVNSIGG----------K 4108
L S +WW+ D +G+VPA Y K + E T Q Q+ ++ G +
Sbjct: 847 LEKSTPEWWRALKRDGTEGYVPANYCKVVPGESVTVTQTTQKTTTTVEGNETKSSVVAER 906
Query: 4107 QSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQ 3928
Q +I + Y+ L L + R+R L + K + RE +D W + ++A + E
Sbjct: 907 QHKISNDYRELRRLADVRRRLLSDNIKLLRFYRECDDFERWKEIEVSLADEPSP----EH 962
Query: 3927 VEVLQKKFDDFKGDLKANE-VRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALX 3751
V ++KFD + D+K N +L+ +N IA L S G ++ +I + +NA W L
Sbjct: 963 VTAFRRKFDKLEADMKTNGGTQLKHINDIANDLISEGHGQSR-QIENRQHKINAMWENLE 1021
Query: 3750 XXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVE 3571
+L + V F + R+W+ K + LD D++S+Q L E
Sbjct: 1022 RLRKQRAVRLEATERVADFDTTCESAREWMLGKFEQLDRNP--NDVKSLQNL-------E 1072
Query: 3570 RDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSY 3391
RDL L DKI +L++ A +++ HPE A I EL L +A + S
Sbjct: 1073 RDLKPLEDKIAALEKLAAAVKKDHPEEAAAIERKIAELRTLHADLLRRAQEKMLLAEQSQ 1132
Query: 3390 DYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFD 3211
+ F S RD+M WI + + DV AE LL++H E +I + +
Sbjct: 1133 GKEMFESALRDMMSWIEKTRKGMMEDVHPVDVAEAEELLKKHYELGEQIKDKKYEVEYCQ 1192
Query: 3210 QFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADT 3031
+ G +LL +E +LQ + L D + R IL Q L+LQLF R+ E+ D
Sbjct: 1193 ELGRRLLERSPRMP-KVEEQLQALVSEMAALRDLYRRRDTILKQQLDLQLFNRESERIDA 1251
Query: 3030 WMSAREAFLAQEDPSGDNVES---LIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYD 2860
EAFL + D GD+VES L+K+H D + ++ QE +++ A+ +IK H D
Sbjct: 1252 ATKGHEAFL-EFDNLGDSVESVENLLKRHRDLEAKLDAQEARLEAFSRTADDMIKAQHAD 1310
Query: 2859 SPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQ--E 2686
S + ++R +L R ++ A Q++ +L S Q+ R+ADE+ WM EK ++ +
Sbjct: 1311 SAYIEQRRRDVLARREAVRRAAAQRKKQLEASLEYQEMRREADEVMGWMHEKAKLVASGD 1370
Query: 2685 ENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKAL 2506
+ P+ I + K +AFEAE+ AN RI I + G+NL+ K V ++ +
Sbjct: 1371 DAALAPSAIPHRLLKHEAFEAEIIANESRIQQINREGDNLV--GKNHYESPNVEKVVRQV 1428
Query: 2505 NDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENL 2326
N QW L K K RL++A QK ++D L E+E L S+D G DL SV++L
Sbjct: 1429 NAQWGDLKKQVYNKGQRLRQAADQKGLDRILEDAHAKLDEMESALNSKDQGLDLRSVKDL 1488
Query: 2325 LKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDR 2146
L+KH++LE ++ + +++ ++ + + + +I + RY +K A R
Sbjct: 1489 LQKHTVLEQEMGLYGNKLADIENRGKKMAVEGHYDADKIHMTVGDLLKRYAAMKGPAQRR 1548
Query: 2145 RDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASH 1966
+ L ++ HQ D+D E WI EKK + SS D GR L N+ +K +++ E+ H
Sbjct: 1549 KGDLDESRLWHQLVFDVDCELQWIAEKKPIASSQDCGRTLTEALNMVKKQEQLEAEVNQH 1608
Query: 1965 EPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQ 1786
Q+ V + +L++ A QIK + +LE +W ++R L +R +D Q
Sbjct: 1609 GGQIDKVLGQASKLVKRHHPAS---SQIKAKSGELESAWSELRRLLRSRRAIVDWGVKEQ 1665
Query: 1785 AFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKG 1606
+L D E E+WMNEK+ L S+++G + + LL KH D+ ++Q + L K
Sbjct: 1666 QYLFDAAEVESWMNEKRNALASEDYGNDEDAARKLLAKHRALCEDMTTYRQWLEKLDVKC 1725
Query: 1605 DTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIA 1426
L+ + H ++R D+L + +AE R L D ++M + +E WI
Sbjct: 1726 SELVQSDRPHVDRFQKRQDELVHEFDSLSKLAEDRRNALEDAVCLYEYMRESADLEQWIG 1785
Query: 1425 EKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSP- 1249
E+ Q EDF D ++ L +K + F + G +R T + + + P
Sbjct: 1786 EQLQTALCEDFAEDYEHLKELQSKFDEFKQSVKT----GSERFTSCETAANTILRRNPPF 1841
Query: 1248 --AIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENA 1075
+ K+ + W L + E R EEL+ F + F W +
Sbjct: 1842 ARDVVKKQEKLRSAWNLLCEYIETR-------TAKLAVAEELH-RFHRDVDEFEQWMADK 1893
Query: 1074 EEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQL-QDLDRRIKSFNVGPNPYTW 898
++ + ++ + +L H + +A+ +L ++ +R K++ G
Sbjct: 1894 MANMPRDLG-RDVKHVHSLWQQHEALDKETHNAQPRLTKLVEEAERLKKAYPGGNAEQIG 1952
Query: 897 FTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLR 784
L + W L+ +R+ L N K+R
Sbjct: 1953 GRQQTLVEEWEELRNATDDRKDMLRAAFDLHTFNGKVR 1990
Score = 546 bits (1406), Expect = e-153
Identities = 362/1352 (26%), Positives = 660/1352 (48%), Gaps = 46/1352 (3%)
Frame = -1
Query: 7152 IFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEK---LQTAQEENFRDPS--NLQAKI 6988
+ ++ + + L++A F D ++ WI EK ++ A++++ S ++
Sbjct: 2176 LLREDIEARHVMLKDAFALASFGSDVAQIEAWIDEKTNGIRKARDQSSESISIEEKMKRL 2235
Query: 6987 QKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKG 6808
Q H+A EAEV A+ KTI + ++ H S+ I EL+ W +
Sbjct: 2236 QTHQALEAEVAAN-KTIVDQILHRGQQLKSLHRNSK-IGDTCNELNVKWSQLAGACDDQS 2293
Query: 6807 IKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQ 6628
L++A LL F + + +L WI EKE V+ DMG D+EH +L + D + +
Sbjct: 2294 RALEEARDLLRFKQLVENVLTWINEKEVLVSTADMGRDMEHCRMLLERLDGTRSDSTVDE 2353
Query: 6627 YRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNR 6448
++EIN+ +KLV++G + DQ+ K++ +N+ W L + + L A +V FNR
Sbjct: 2354 QTLDEINRLGEKLVKQGRTSRDQVQKEQQRLNEKWRLLLGQLSHYRTELVAAMEVHTFNR 2413
Query: 6447 DADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLA 6268
D ++T I EK A+ SDD+G+D +V+ L RK ERD++A+ K++ +K+A K+
Sbjct: 2414 DVEDTDERIHEKIAAMKSDDFGKDFASVELLVRKQSALERDMSAIHQKLISHDKDAQKIL 2473
Query: 6267 ETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKA 6088
E P E+I + +W L E A+ R D L RSF+L+++L D + W ++
Sbjct: 2474 EKRPPLKESILDSLKKLEESWKKLSEAAELRNDKLNRSFKLYKYLDDVKKTEQWANQVRN 2533
Query: 6087 VIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKL 5908
+ + + KD +GA LLE H E K EID RAD Q GQ L + EVQ
Sbjct: 2534 KMTSHQTPKDSSGARKLLEQHHERKAEIDGRADELRQLHEEGQALNQEQPEHKAEVQRAH 2593
Query: 5907 EKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSV 5728
+++ + + L WE + ++ ++ L+ + Q E W+ +E ++ +LGD+ D+V
Sbjct: 2594 KRVQNSEHQLRQTWESEKGTLQKLLEWMLWCDEAVQCEQWLADKENQVSRGELGDTSDAV 2653
Query: 5727 EHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXX 5548
E LIK H FE+++ Q EKI+ L + A L+ G + D+
Sbjct: 2654 EMLIKGHSAFEETVRKQSEKIDVLVKNADALVSGGNNYRADIITRKDEVTARHDLLLKSM 2713
Query: 5547 XXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQELK 5368
R + L++S + F R C E++ WIT KL A D+S+LD TN+R KLQKH+ F+ EL
Sbjct: 2714 SKRKDMLEDSKRYHEFIRHCGELIIWITAKLQLAYDESFLDHTNLRSKLQKHMAFDSELV 2773
Query: 5367 ANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQ 5188
NE RL ++ GE+++ HF ++ + +L ++ + W+EL + K +LREA
Sbjct: 2774 ENEKRLSNVERQGEELVADNHFMSEQVKAQLVELRSGWDELRTKSALKTQRLREAFELHS 2833
Query: 5187 FNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQ 5008
R +ED+E WL ++EG++ASED+G+D++S + L KK+ ++++ +D V + + A+
Sbjct: 2834 LQRKVEDLEKWLDKVEGELASEDHGRDMLSTELLIKKLDTLQTEIAGRSDAVVEMMKKAR 2893
Query: 5007 QFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIRE 4828
+ + + A +++ E ++ RY+ L +P++ R+ L ++ + + E++L W+ +
Sbjct: 2894 ELRVQGSAAADDCLKQAEQVEARYSGLDEPVQIRRENLVDAQAFFEWVKAAEEDLEWLSD 2953
Query: 4827 KEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIR 4648
K +A S G L +L KK AL E+ S ++ DMI+Q HF + I+
Sbjct: 2954 KMPLASSGESGDSLQSALSLQKKHAALEKELETRQSAMDDTEKRGKDMIRQRHFASGHIQ 3013
Query: 4647 DKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDE 4468
L +L LK RR L +++ AH+Y ++ EA+ W+ E+ P+ S + G+D+
Sbjct: 3014 KILDRLSTAMLTLKESCGLRRDLLQEAIDAHEYYTEETEAEQWLREQMPLAMSQEMGRDQ 3073
Query: 4467 DSAEALLKKHRALLSDLEAFKGTIEDLRKQ---------------ASQCKYQEQPMGQLG 4333
AE+ L++ L ++E FK I+ L+K+ A++ + E G L
Sbjct: 3074 AGAESHLRRLTVLDKEVELFKNEIDRLKKRADGLLAREHHDAMSIAAKQRKLEALFGDLC 3133
Query: 4332 RDCVLALYDYQEKSPREVSMKKGDVLT------LLNASNRDWWKVEVNDRQGFVP--AAY 4177
R+C + S +++ D L+ AS D+ + ++ D Q + +
Sbjct: 3134 RECARRRTQIVDASKYHKFVRQADDLSDWLREKERTASAEDYGQ-DLEDCQQIIEQFEST 3192
Query: 4176 VKRI----EPGTAQQHAQQQV--------NSIGGKQSEIEDKYQRLMMLGETRKRKLEEA 4033
V+ + E Q +Q+ + SI K ++++ + + + RK+ L A
Sbjct: 3193 VRELAAAGERVALVQRSQEDLLRSGHPYGASITAKGADVQRLWTHVNEVANERKQALNGA 3252
Query: 4032 CKGYQLLREANDLAEWIKSREA--VAAQQE--IGTDLEQVEVLQKKFDDFKGDLKANEVR 3865
+ ++ +EA+ W++ +EA VA +QE DL V+ ++ D+F +KA E +
Sbjct: 3253 RQVHRFDQEADQTLNWLQDKEATGVAMEQEDLSRADLASVKAQLQRHDEFMHGMKAVEKQ 3312
Query: 3864 LQEMNQIATAL-TSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHR 3688
+ E+ A L S T + +R+ D+ + + + +L +Q + +
Sbjct: 3313 VAELCHEAERLWNSFPDTRHHLEVRRL--DMEEQLKDILEAAKKHLERLRHMQSLQSYFQ 3370
Query: 3687 DVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLR 3508
+ E W++ + SE RD+ S ++L R+H+ ++ + + R+
Sbjct: 3371 EYREMMQWMKNMQTTMTSEQLPRDVASCESLVRRHDEYNLEMQGRKPFVDDFARQGRRMI 3430
Query: 3507 QSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQ 3328
QS +++I + L + W L +R E ++ D Q++ + L W+
Sbjct: 3431 QSSHVLSQEIQEKVEVLEKSWEMLCEIWKDRAELYEENMDVQKWKQNAEQLDSWLEERAG 3490
Query: 3327 LVSSQ-ELANDVTGAEALLERHQEYRTEIDSR 3235
L+ + + V AE+ L ++ ++++
Sbjct: 3491 LLGDDWRMVDSVEMAESHLRDFDDFLVTLEAQ 3522
Score = 520 bits (1340), Expect = e-145
Identities = 463/2074 (22%), Positives = 898/2074 (42%), Gaps = 64/2074 (3%)
Frame = -1
Query: 7206 ETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQE 7027
++ +DI +R ++ + + + L EAR Q + +D +E WI EK+ +
Sbjct: 700 QSKEDIQRRLTQMNQGWERLRVAVDALGNWLSEARHAQQYFQDVNEAESWIREKMPLVKS 759
Query: 7026 ENF-RDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQ---HNHFASEHIKKRLE 6859
++ RD ++ +Q+H E E++A+ I L++ + + H S+ +++ E
Sbjct: 760 DDLGRDEGAAESLLQRHARLEEEIRAYKNDITRLEEMQSQLANSAFHTATTSQSVQE-TE 818
Query: 6858 ELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREK----ETYVTAEDMGMDL 6691
E+ G+++ + L + E +W K E YV A
Sbjct: 819 EVTVPQIEMAYKYEGNGMRVAKGEVLALLEKSTPE--WWRALKRDGTEGYVPA------- 869
Query: 6690 EHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLN 6511
++ K + + + Q VE ++ + +++ +++ + L
Sbjct: 870 -----------NYCKVVPGESVTVTQTTQKTTTTVEGNETKSSVVAERQHKISNDYRELR 918
Query: 6510 TLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTE 6331
LA R+ L ++ RF R+ D+ W K++ +S D +V A +RK + E
Sbjct: 919 RLADVRRRLLSDNIKLLRFYRECDDFERW---KEIEVSLADEPSP-EHVTAFRRKFDKLE 974
Query: 6330 RDLAALEGKMLQ-LEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERS 6154
D+ G L+ + A+ L ++ I + A W L+ + R LE +
Sbjct: 975 ADMKTNGGTQLKHINDIANDLISEGHGQSRQIENRQHKINAMWENLERLRKQRAVRLEAT 1034
Query: 6153 FQLHRFLADYRDLISW-IGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQ 5977
++ F W +G + + D DV L++ + ++ + + +
Sbjct: 1035 ERVADFDTTCESAREWMLGKFEQL---DRNPNDVKS----LQNLERDLKPLEDKIAALEK 1087
Query: 5976 TASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQA 5797
A+A +K E+ ++ K+ +L + LL +E+ +L EQ ++F
Sbjct: 1088 LAAAVKK---DHPEEAAAIERKIAELRTLHADLLRRAQEKMLLAEQSQGKEMFESALRDM 1144
Query: 5796 ETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHY 5617
+W+ K + + E L+KKH + + + ++ ++ E +L++ +
Sbjct: 1145 MSWIEKTRKGMMEDVHPVDVAEAEELLKKHYELGEQIKDKKYEVEYCQELGRRLLE-RSP 1203
Query: 5616 AADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDD 5437
V E R LK+ Q F+R+ + + + + D
Sbjct: 1204 RMPKVEEQLQALVSEMAALRDLYRRRDTILKQQLDLQLFNRESERIDAATKGHEAFLEFD 1263
Query: 5436 SYLDPT-NIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNN 5260
+ D ++ L++H + E +L A E RL+ T + +I + H + +I R R V
Sbjct: 1264 NLGDSVESVENLLKRHRDLEAKLDAQEARLEAFSRTADDMIKAQHADSAYIEQRRRDVLA 1323
Query: 5259 LWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVAS-EDYGKDLVSVQNLQ 5083
+ A ++ +L + Q+ R ++V W+ E VAS +D ++ +
Sbjct: 1324 RREAVRRAAAQRKKQLEASLEYQEMRREADEVMGWMHEKAKLVASGDDAALAPSAIPHRL 1383
Query: 5082 KKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRK 4903
K E++ A+ R+ I + + H+ +P + + + ++ L+ + +
Sbjct: 1384 LKHEAFEAEIIANESRIQQINREGDNLVGKNHYESPNVEKVVRQVNAQWGDLKKQVYNKG 1443
Query: 4902 RKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHD 4723
++L ++ L R +ED A + E E S ++G DL V++L++K L E+ +
Sbjct: 1444 QRLRQAADQKGLDRILEDAHAKLDEMESALNSKDQGLDLRSVKDLLQKHTVLEQEMGLYG 1503
Query: 4722 SQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLS 4543
+++ + + M +GH+ A +I + L + +K A++R+ DLD+S HQ +
Sbjct: 1504 NKLADIENRGKKMAVEGHYDADKIHMTVGDLLKRYAAMKGPAQRRKGDLDESRLWHQLVF 1563
Query: 4542 DANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCK 4363
D + W++EK+PI S D G+ A ++KK L +++ G I+ + QAS+
Sbjct: 1564 DVDCELQWIAEKKPIASSQDCGRTLTEALNMVKKQEQLEAEVNQHGGQIDKVLGQASKLV 1623
Query: 4362 YQEQPMGQLGRDCVLALYDYQEKSPREVSMKKGDV-------LTLLNASNRDWWKVEVND 4204
+ P + L + R + ++ V L +A+ + W +N+
Sbjct: 1624 KRHHPASSQIKAKSGELESAWSELRRLLRSRRAIVDWGVKEQQYLFDAAEVESW---MNE 1680
Query: 4203 RQGFVPAAYVKRIEPGTAQQHA------------QQQVNSIGGKQSEI-------EDKYQ 4081
++ + + E + A +Q + + K SE+ D++Q
Sbjct: 1681 KRNALASEDYGNDEDAARKLLAKHRALCEDMTTYRQWLEKLDVKCSELVQSDRPHVDRFQ 1740
Query: 4080 R-----------LMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDL 3934
+ L L E R+ LE+A Y+ +RE+ DL +WI + A ++ D
Sbjct: 1741 KRQDELVHEFDSLSKLAEDRRNALEDAVCLYEYMRESADLEQWIGEQLQTALCEDFAEDY 1800
Query: 3933 EQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRAL 3754
E ++ LQ KFD+FK +K R A + +++Q E L + W L
Sbjct: 1801 EHLKELQSKFDEFKQSVKTGSERFTSCETAANTILRRNPPFARDVVKKQ-EKLRSAWNLL 1859
Query: 3753 XXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGV 3574
+L A E+ RFHRDVDE W+ +K A D GRD++ V +L ++HE +
Sbjct: 1860 CEYIETRTAKLAVAEELHRFHRDVDEFEQWMADK-MANMPRDLGRDVKHVHSLWQQHEAL 1918
Query: 3573 ERDLAALGDKIKSLDEKANRLRQSHPEA-AEQIYDLQRELNEQWNRLTSKANNRKEKLLD 3397
+++ ++ L E+A RL++++P AEQI Q+ L E+W L + ++RK+ L
Sbjct: 1919 DKETHNAQPRLTKLVEEAERLKKAYPGGNAEQIGGRQQTLVEEWEELRNATDDRKDMLRA 1978
Query: 3396 SYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQA 3217
++D F RDL+ W + S ND+ AE L H E+D+R F
Sbjct: 1979 AFDLHTFNGKVRDLLAWTDLTISDIQSDLQINDLQQAEWLQTEHSRLSHEMDAREPEFTR 2038
Query: 3216 FDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQA 3037
G +++N+ HYA +I+N+ + + A + L W R L Q ++ F R+ +Q
Sbjct: 2039 LVSDGEKMVNAQHYATEEIKNKTRLLKTALERLRSEWTLRNGYLSQAVQWHAFQREAKQI 2098
Query: 3036 DTWMSAREAFLAQEDPSGD--NVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHY 2863
+ ++ L G +VES K+ + F+KA++T +E+ L A L+K+ H
Sbjct: 2099 IASIGSKRTTLRSLAVGGSVADVESQKKRLDTFEKALSTLDERTATLDHTANELVKSRHM 2158
Query: 2862 DSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEE 2683
+S + + ++ + L+E + + L ++ L F D +IE W+ EK ++
Sbjct: 2159 ESKNIAMWQSKVHEELKLLREDIEARHVMLKDAFALASFGSDVAQIEAWIDEKTNGIRKA 2218
Query: 2682 NYRDPTNI-----QQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSAR 2518
+ +I ++ Q QA EAE+ AN + I+ G L K + +
Sbjct: 2219 RDQSSESISIEEKMKRLQTHQALEAEVAANKTIVDQILHRGQQL----KSLHRNSKIGDT 2274
Query: 2517 LKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLAS 2338
LN +W L ++S L+EA F V+++ W+ E E+L+ + D G+D+
Sbjct: 2275 CNELNVKWSQLAGACDDQSRALEEARDLLRFKQLVENVLTWINEKEVLVSTADMGRDMEH 2334
Query: 2337 VENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKM 2158
LL++ +D + + E+N + L++ + Q+ + ++ + +++ +
Sbjct: 2335 CRMLLERLDGTRSDSTVDEQTLDEINRLGEKLVKQGRTSRDQVQKEQQRLNEKWRLLLGQ 2394
Query: 2157 ATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTE 1978
+ R +L A+ VH F RD++D + I EK + SDD+G+D V+ L RK ++ +
Sbjct: 2395 LSHYRTELVAAMEVHTFNRDVEDTDERIHEKIAAMKSDDFGKDFASVELLVRKQSALERD 2454
Query: 1977 L-ASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDE 1801
+ A H+ +S K +++L ++ I ++ LE+SW ++ + R+ +L+
Sbjct: 2455 MSAIHQKLISHDK-DAQKILEKRPPL---KESILDSLKKLEESWKKLSEAAELRNDKLNR 2510
Query: 1800 SEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVAD 1621
S +L DV++ E W N+ + + S ++ +G + LL++H + +++ +
Sbjct: 2511 SFKLYKYLDDVKKTEQWANQVRNKMTSHQTPKDSSGARKLLEQHHERKAEIDGRADELRQ 2570
Query: 1620 LINKGDTLIHNGNHHAPHIK---QRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKC 1450
L +G L H ++ +R +L + +G L KL L++M C
Sbjct: 2571 LHEEGQALNQEQPEHKAEVQRAHKRVQNSEHQLRQTWESEKGTLQKL------LEWMLWC 2624
Query: 1449 DVV---ESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQ 1279
D E W+A+KE QV + G +V++L+ AF+ + + E I + + D
Sbjct: 2625 DEAVQCEQWLADKENQVSRGELGDTSDAVEMLIKGHSAFEETVRK-QSEKIDVLVKNADA 2683
Query: 1278 LVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARR 1177
LVS + I R V R LL R+
Sbjct: 2684 LVSGGNNYRADIITRKDEVTARHDLLLKSMSKRK 2717
Score = 463 bits (1192), Expect = e-128
Identities = 424/2074 (20%), Positives = 883/2074 (42%), Gaps = 66/2074 (3%)
Frame = -1
Query: 7200 ADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEEN 7021
AD IH ++L Y+ K +Q ++ L+E+R + D D WI EK A ++
Sbjct: 1524 ADKIHMTVGDLLKRYAAMKGPAQRRKGDLDESRLWHQLVFDVDCELQWIAEKKPIASSQD 1583
Query: 7020 F-RDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHAL 6844
R + ++K E EAEV H I + + +++ +H AS IK + EL +
Sbjct: 1584 CGRTLTEALNMVKKQEQLEAEVNQHGGQIDKVLGQASKLVKRHHPASSQIKAKSGELESA 1643
Query: 6843 WXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRK 6664
W + + +K ++ E+ W+ EK + +ED G D + L K
Sbjct: 1644 WSELRRLLRSRRAIVDWGVKEQQYLFDAAEVESWMNEKRNALASEDYGNDEDAARKLLAK 1703
Query: 6663 FDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEG 6484
+++ ++ + +++ +LV+ D+ K++D++ + L+ LA R+
Sbjct: 1704 HRALCEDMTTYRQWLEKLDVKCSELVQSDRPHVDRFQKRQDELVHEFDSLSKLAEDRRNA 1763
Query: 6483 LFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGK 6304
L A + + R++ + WIGE+ +D+ D +++ LQ K + ++ + +
Sbjct: 1764 LEDAVCLYEYMRESADLEQWIGEQLQTALCEDFAEDYEHLKELQSKFDEFKQSVKTGSER 1823
Query: 6303 MLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADY 6124
E A+ + +P A + +K + ++AWN L E + R L + +LHRF D
Sbjct: 1824 FTSCETAANTILRRNPPFARDVVKKQEKLRSAWNLLCEYIETRTAKLAVAEELHRFHRDV 1883
Query: 6123 RDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEM 5944
+ W+ D A + D L +DV +L + H+ E + ++L +
Sbjct: 1884 DEFEQWMADKMANMPRD-LGRDVKHVHSLWQQHEALDKETHNAQPRLTKLVEEAERL-KK 1941
Query: 5943 GIP--ESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEA 5770
P + ++ + + L E L ++R+ + DL F W + +
Sbjct: 1942 AYPGGNAEQIGGRQQTLVEEWEELRNATDDRKDMLRAAFDLHTFNGKVRDLLAWTDLTIS 2001
Query: 5769 FLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXX 5590
+ + + L E L +H + A+E + L K++ QHYA +++
Sbjct: 2002 DIQSDLQINDLQQAEWLQTEHSRLSHEMDAREPEFTRLVSDGEKMVNAQHYATEEIKNKT 2061
Query: 5589 XXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARD----DSYLDP 5422
R L ++ + F R+ ++++ I K +T R S D
Sbjct: 2062 RLLKTALERLRSEWTLRNGYLSQAVQWHAFQREAKQIIASIGSKRTTLRSLAVGGSVADV 2121
Query: 5421 TNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELV 5242
+ + +L FE+ L + R + T +++ S H + +I +V+ L
Sbjct: 2122 ESQKKRLD---TFEKALSTLDERTATLDHTANELVKSRHMESKNIAMWQSKVHEELKLLR 2178
Query: 5241 DATNKKGAKLREAGNEQQFNRNIEDVEAWLSE-LEGQVASEDYGKDLVSVQNLQKKI--- 5074
+ + L++A F ++ +EAW+ E G + D + +S++ K++
Sbjct: 2179 EDIEARHVMLKDAFALASFGSDVAQIEAWIDEKTNGIRKARDQSSESISIEEKMKRLQTH 2238
Query: 5073 GLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKL 4894
+E++ A+ VD I QQ + H N+ + E L +++ L + + R L
Sbjct: 2239 QALEAEVAANKTIVDQILHRGQQL-KSLHRNSKIGDTCNE-LNVKWSQLAGACDDQSRAL 2296
Query: 4893 GESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQI 4714
E+ + + +E+ L WI EKE + + + GRD+ + L+++ ++ + +
Sbjct: 2297 EEARDLLRFKQLVENVLTWINEKEVLVSTADMGRDMEHCRMLLERLDGTRSDSTVDEQTL 2356
Query: 4713 ESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDAN 4534
+ ++ +++QG +++ + +L + WR+L + RT+L +++ H + D
Sbjct: 2357 DEINRLGEKLVKQGRTSRDQVQKEQQRLNEKWRLLLGQLSHYRTELVAAMEVHTFNRDVE 2416
Query: 4533 EADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQE 4354
+ D + EK + S D+GKD S E L++K AL D+ A + K A + +
Sbjct: 2417 DTDERIHEKIAAMKSDDFGKDFASVELLVRKQSALERDMSAIHQKLISHDKDAQKILEKR 2476
Query: 4353 QPMGQLGRDCVLALYDYQEKSPREVSMKKGDVLT--------LLNASNRDWWKVEVNDR- 4201
P+ + D + L + +K E + + D L L + + W +V ++
Sbjct: 2477 PPLKESILDSLKKLEESWKKL-SEAAELRNDKLNRSFKLYKYLDDVKKTEQWANQVRNKM 2535
Query: 4200 ------------QGFVPAAYVKRIE-PGTAQQHAQ--QQVNSIGGKQSEIEDKYQR---- 4078
+ + + ++ E G A + Q ++ ++ +Q E + + QR
Sbjct: 2536 TSHQTPKDSSGARKLLEQHHERKAEIDGRADELRQLHEEGQALNQEQPEHKAEVQRAHKR 2595
Query: 4077 -------LMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEV 3919
L E+ K L++ + EA +W+ +E ++ E+G + VE+
Sbjct: 2596 VQNSEHQLRQTWESEKGTLQKLLEWMLWCDEAVQCEQWLADKENQVSRGELGDTSDAVEM 2655
Query: 3918 LQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXX 3739
L K F+ ++ ++ + + A AL S G A I ++ +++ AR L
Sbjct: 2656 LIKGHSAFEETVRKQSEKIDVLVKNADALVSGGNNYRADIITRK-DEVTARHDLLLKSMS 2714
Query: 3738 XXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLA 3559
L + F R E WI K E F D ++++ +KH + +L
Sbjct: 2715 KRKDMLEDSKRYHEFIRHCGELIIWITAKLQLAYDESF-LDHTNLRSKLQKHMAFDSELV 2773
Query: 3558 ALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQR 3379
++ +++ + L + +EQ+ EL W+ L +K+ + ++L ++++
Sbjct: 2774 ENEKRLSNVERQGEELVADNHFMSEQVKAQLVELRSGWDELRTKSALKTQRLREAFELHS 2833
Query: 3378 FLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGN 3199
DL +W+ + ++S++ D+ E L+++ +TEI R+ +
Sbjct: 2834 LQRKVEDLEKWLDKVEGELASEDHGRDMLSTELLIKKLDTLQTEIAGRSDAVVEMMKKAR 2893
Query: 3198 QLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSA 3019
+L AA D + + V GL++ RR L + + E+ W+S
Sbjct: 2894 ELRVQGSAAADDCLKQAEQVEARYSGLDEPVQIRRENLVDAQAFFEWVKAAEEDLEWLSD 2953
Query: 3018 REAFLAQEDPSGDNVE---SLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAV 2848
+ LA SGD+++ SL KKH +K + T++ + + + +I+ H+ S +
Sbjct: 2954 KMP-LASSGESGDSLQSALSLQKKHAALEKELETRQSAMDDTEKRGKDMIRQRHFASGHI 3012
Query: 2847 TRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIA-QEENYRD 2671
+ D++ LKE+ +R L E+ ++ + E E W+ E+ +A +E RD
Sbjct: 3013 QKILDRLSTAMLTLKESCGLRRDLLQEAIDAHEYYTEETEAEQWLREQMPLAMSQEMGRD 3072
Query: 2670 PTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWD 2491
+ ++ + E+ + I + + + L+ A+ +++A+ + L +
Sbjct: 3073 QAGAESHLRRLTVLDKEVELFKNEIDRLKKRADGLL--AREHHDAMSIAAKQRKLEALFG 3130
Query: 2490 LLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHS 2311
L + + ++ +A+K F+ DL WL E E +EDYG+DL + ++++
Sbjct: 3131 DLCRECARRRTQIVDASKYHKFVRQADDLSDWLREKERTASAEDYGQDLEDCQQIIEQFE 3190
Query: 2310 LLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLS 2131
++ A +RV + + LL + G I + + + V ++A +R+ L+
Sbjct: 3191 STVRELAAAGERVALVQRSQEDLLRSGHPYGASITAKGADVQRLWTHVNEVANERKQALN 3250
Query: 2130 KALNVHQFFRDIDDEESWIKEKK---LLVSSDDYGR-DLPGVQNLRRKHRRIDTELASHE 1963
A VH+F ++ D +W+++K+ + + +D R DL V+ ++H + + E
Sbjct: 3251 GARQVHRFDQEADQTLNWLQDKEATGVAMEQEDLSRADLASVKAQLQRHDEFMHGMKAVE 3310
Query: 1962 PQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQA 1783
QV+ + + E L S + ++ R D+E+ I + +RL ++ Q+
Sbjct: 3311 KQVAELCHEAERLWNSFPDT---RHHLEVRRLDMEEQLKDILEAAKKHLERLRHMQSLQS 3367
Query: 1782 FLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGD 1603
+ + E WM Q + S+ ++A + L+++HD + ++++ K V D +G
Sbjct: 3368 YFQEYREMMQWMKNMQTTMTSEQLPRDVASCESLVRRHDEYNLEMQGRKPFVDDFARQGR 3427
Query: 1602 TLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAE 1423
+I + + + I+++ + L + + + R +N ++ + ++SW+ E
Sbjct: 3428 RMIQSSHVLSQEIQEKVEVLEKSWEMLCEIWKDRAELYEENMDVQKWKQNAEQLDSWLEE 3487
Query: 1422 KEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEH-----EGIQRITELK---DQLVSS 1267
+ + D R + SV++ + FD L E E ++R+T ++ +L S
Sbjct: 3488 RAGLL--GDDWRMVDSVEMAESHLRDFDDFLVTLEAQNEKCEMVKRLTLVEQNFSRLRSK 3545
Query: 1266 EHQQSPAIE----KRHTNVIQRWQNLLAHSEARR 1177
E ++ E +R T I N+LA+ R
Sbjct: 3546 EIDRAKIAEEDQKRRDTIKIVEKGNILANRRQER 3579
Score = 390 bits (1002), Expect = e-106
Identities = 440/2200 (20%), Positives = 898/2200 (40%), Gaps = 71/2200 (3%)
Frame = -1
Query: 6984 KHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGI 6805
KH+ +A++ AH ++ L + N I+H + ++++L+E+ + + + +
Sbjct: 564 KHDLVDAQINAHGSLLSKLSQAANNYIRHKEEQFDVLQRKLDEVTSQYNTLVELCRSRRL 623
Query: 6804 KLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQY 6625
L++A L FI+ +E + W+ EKE T D+ V + + E+ H
Sbjct: 624 ALERARSLFQFIQDHEEEMAWLAEKEKLCTTALNSGDISAVPQTTLLYKNVEMEMQTHWA 683
Query: 6624 RINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRD 6445
R + ++LV+ G S+ D I ++ +N W RL L A Q++ +D
Sbjct: 684 RSKGMIAGGERLVQSGQSKED-IQRRLTQMNQGWERLRVAVDALGNWLSEARHAQQYFQD 742
Query: 6444 ADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAE 6265
+E +WI EK + SDD GRD ++L ++H E ++ A + + +LE+ +LA
Sbjct: 743 VNEAESWIREKMPLVKSDDLGRDEGAAESLLQRHARLEEEIRAYKNDITRLEEMQSQLAN 802
Query: 6264 THPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAV 6085
+ A + + ++ ++ +G+ + L + W
Sbjct: 803 SAFHTATTSQSVQETEEVTVPQIEMAYKYEGNGMRVAKGEVLALLEKSTPEWWRA----- 857
Query: 6084 IGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLE 5905
L +D G E + ++ + + + + QT VE +S V E+
Sbjct: 858 -----LKRD--GTEGYVPAN--YCKVVPGESVTVTQTTQKTTTTVEGNETKSSVVAERQH 908
Query: 5904 KLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVE 5725
K+ ++ L L + RR L + L FYR+ + E W + E LA+ S E
Sbjct: 909 KISNDYRELRRLADVRRRLLSDNIKLLRFYRECDDFERW-KEIEVSLADE------PSPE 961
Query: 5724 HLIKKHEDFEKSLAAQE----EKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXX 5557
H+ F+K A + ++ +++ A LI H + +
Sbjct: 962 HVTAFRRKFDKLEADMKTNGGTQLKHINDIANDLISEGHGQSRQIENRQHKINAMWENLE 1021
Query: 5556 XXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQ 5377
R L+ + + FD C+ W+ K + +P +++ LQ N E+
Sbjct: 1022 RLRKQRAVRLEATERVADFDTTCESAREWMLGKF----EQLDRNPNDVK-SLQ---NLER 1073
Query: 5376 ELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGN 5197
+LK E+++ + + A I ++ ++ L +L+ +K ++
Sbjct: 1074 DLKPLEDKIAALEKLAAAVKKDHPEEAAAIERKIAELRTLHADLLRRAQEKMLLAEQSQG 1133
Query: 5196 EQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQ 5017
++ F + D+ +W+ + + + + D+ + L KK + V+ ++
Sbjct: 1134 KEMFESALRDMMSWIEKTRKGMMEDVHPVDVAEAEELLKKHYELGEQIKDKKYEVEYCQE 1193
Query: 5016 LAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLF-RDIEDELA 4840
L ++ E P + + + L ALRD L +R+ + + QLF R+ E A
Sbjct: 1194 LGRRLLERSP-RMPKVEEQLQALVSEMAALRD-LYRRRDTILKQQLDLQLFNRESERIDA 1251
Query: 4839 WIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLA 4660
+ E N G + V+NL+K+ + L A++ ++++E+ S A+DMI+ H +
Sbjct: 1252 ATKGHEAFLEFDNLGDSVESVENLLKRHRDLEAKLDAQEARLEAFSRTADDMIKAQHADS 1311
Query: 4659 PEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDY 4480
I + + ++ A +R+ L+ SL+ + +A+E WM EK +V S D
Sbjct: 1312 AYIEQRRRDVLARREAVRRAAAQRKKQLEASLEYQEMRREADEVMGWMHEKAKLVASGDD 1371
Query: 4479 GKDEDSA-EALLKKHRALLSDLEAFKGTIEDLRKQASQC------------KYQEQPMGQ 4339
SA L KH A +++ A + I+ + ++ K Q Q
Sbjct: 1372 AALAPSAIPHRLLKHEAFEAEIIANESRIQQINREGDNLVGKNHYESPNVEKVVRQVNAQ 1431
Query: 4338 LGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIEP 4159
G D +Y+ ++ + K D + + D + +N + + VK +
Sbjct: 1432 WG-DLKKQVYNKGQRLRQAADQKGLDRILEDAHAKLDEMESALNSKDQGLDLRSVKDL-- 1488
Query: 4158 GTAQQHA--QQQVNSIGGKQSEIEDKYQRLMMLG-------------------------E 4060
Q+H +Q++ G K ++IE++ +++ + G +
Sbjct: 1489 --LQKHTVLEQEMGLYGNKLADIENRGKKMAVEGHYDADKIHMTVGDLLKRYAAMKGPAQ 1546
Query: 4059 TRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLK 3880
RK L+E+ +QL+ + + +WI ++ +A+ Q+ G L + + KK + + ++
Sbjct: 1547 RRKGDLDESRLWHQLVFDVDCELQWIAEKKPIASSQDCGRTLTEALNMVKKQEQLEAEVN 1606
Query: 3879 ANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQ 3700
+ ++ ++ A+ L ++ +I+ + +L + W L + + Q
Sbjct: 1607 QHGGQIDKVLGQASKLVKRHHPASS-QIKAKSGELESAWSELRRLLRSRRAIVDWGVKEQ 1665
Query: 3699 RFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKA 3520
++ D E W+ EK +AL SED+G D + + L KH + D+ ++ LD K
Sbjct: 1666 QYLFDAAEVESWMNEKRNALASEDYGNDEDAARKLLAKHRALCEDMTTYRQWLEKLDVKC 1725
Query: 3519 NRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIA 3340
+ L QS ++ Q EL +++ L+ A +R+ L D+ ++ + DL QWI
Sbjct: 1726 SELVQSDRPHVDRFQKRQDELVHEFDSLSKLAEDRRNALEDAVCLYEYMRESADLEQWIG 1785
Query: 3339 SMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDI 3160
Q ++ A D + L + E++ + + + F + + N +L + A D+
Sbjct: 1786 EQLQTALCEDFAEDYEHLKELQSKFDEFKQSVKTGSERFTSCETAANTILRRNPPFARDV 1845
Query: 3159 ENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQE-DPSG 2983
+ + + A L + R L EL F+RD ++ + WM+ + A + ++
Sbjct: 1846 VKKQEKLRSAWNLLCEYIETRTAKLAVAEELHRFHRDVDEFEQWMADKMANMPRDLGRDV 1905
Query: 2982 DNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIK-NNHYDSPAVTRKRDQILDRWNGL 2806
+V SL ++HE DK + + ++ L AE L K ++ + ++ +++ W L
Sbjct: 1906 KHVHSLWQQHEALDKETHNAQPRLTKLVEEAERLKKAYPGGNAEQIGGRQQTLVEEWEEL 1965
Query: 2805 KEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEE-NYRDPTNIQQKHQKQQAF 2629
+ A ++ L + L F+ ++ W Q + D + +
Sbjct: 1966 RNATDDRKDMLRAAFDLHTFNGKVRDLLAWTDLTISDIQSDLQINDLQQAEWLQTEHSRL 2025
Query: 2628 EAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLK 2449
E+ A ++ G ++ NA+ E + + + L + L T ++ L
Sbjct: 2026 SHEMDAREPEFTRLVSDGEKMV-NAQHYATE-EIKNKTRLLKTALERLRSEWTLRNGYLS 2083
Query: 2448 EANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVG 2269
+A + +F K + +G L+S G +A VE+ K+ E + +R
Sbjct: 2084 QAVQWHAFQREAKQIIASIGSKRTTLRSLAVGGSVADVESQKKRLDTFEKALSTLDERTA 2143
Query: 2268 EMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDD 2089
++ A+ L+++ + + IA + + + +++ R L A + F D+
Sbjct: 2144 TLDHTANELVKSRHMESKNIAMWQSKVHEELKLLREDIEARHVMLKDAFALASFGSDVAQ 2203
Query: 2088 EESWIKEKK--LLVSSDDYGRDLPGVQNLRR--KHRRIDTELASHEPQVSLVKLKGEELL 1921
E+WI EK + + D + + ++R H+ ++ E+A+++ V + +G++L
Sbjct: 2204 IEAWIDEKTNGIRKARDQSSESISIEEKMKRLQTHQALEAEVAANKTIVDQILHRGQQLK 2263
Query: 1920 RSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNE 1741
+ +G+ +L W Q+ ++ + L+E+ F VE W+NE
Sbjct: 2264 SLHRNSKIGD-----TCNELNVKWSQLAGACDDQSRALEEARDLLRFKQLVENVLTWINE 2318
Query: 1740 KQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIK 1561
K+ ++ + + G +M + LL++ D + D + +Q + ++ G+ L+ G ++
Sbjct: 2319 KEVLVSTADMGRDMEHCRMLLERLDGTRSDSTVDEQTLDEINRLGEKLVKQGRTSRDQVQ 2378
Query: 1560 QRCDQLRARLIEIESMAEGRLAKLRDN--SAYLQFMWKCDV--VESWIAEKEQQVRSEDF 1393
+ + RL E + G+L+ R +A + DV + I EK ++S+DF
Sbjct: 2379 KE----QQRLNEKWRLLLGQLSHYRTELVAAMEVHTFNRDVEDTDERIHEKIAAMKSDDF 2434
Query: 1392 GRDLSSVQILLTKQEAFDAGLNAFEHEGI------QRITELKDQLVSSEHQQSPAIEKRH 1231
G+D +SV++L+ KQ A + ++A + I Q+I E + L S +E
Sbjct: 2435 GKDFASVELLVRKQSALERDMSAIHQKLISHDKDAQKILEKRPPLKESILDSLKKLE--- 2491
Query: 1230 TNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPV 1051
+ W+ L +E R YL KK W +T
Sbjct: 2492 ----ESWKKLSEAAELRNDKLNRSFKLYK-----YLDDVKKT---EQWANQVRNKMTSHQ 2539
Query: 1050 RCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDT 871
R L + H E + + ++ RQL + + + ++
Sbjct: 2540 TPKDSSGARKLLEQHHERKAEIDGRADELRQLHEEGQALN-----------------QEQ 2582
Query: 870 WRNLQRIIKEREQELAREHQRQEENDKLRREFAKL---------ANAFHAWLTNTRQEMM 718
+ + + ++ EHQ ++ + + KL A WL + +E
Sbjct: 2583 PEHKAEVQRAHKRVQNSEHQLRQTWESEKGTLQKLLEWMLWCDEAVQCEQWLAD--KENQ 2640
Query: 717 EAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERN 598
+ G L + DAVE K A + +R+ EK +L +N
Sbjct: 2641 VSRGELGDTSDAVEMLIKGHSAFEETVRKQSEKIDVLVKN 2680
Score = 347 bits (889), Expect = 3e-93
Identities = 447/2279 (19%), Positives = 889/2279 (38%), Gaps = 123/2279 (5%)
Frame = -1
Query: 7086 KRDADELNVWILEKLQTAQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTG-NA 6910
K D L +W K TA N R N + AF A + +H + + ++ N
Sbjct: 168 KHAKDALLLWCQRK--TAGYPNVRI-ENFTTSWRNGLAFNALIHSHRPDLVDFNRLNPNE 224
Query: 6909 MIQHNHFASEHIKKRLEELHALWXXXXXXXX--XKGIKLQQALKLLHFIRQCDEILYWIR 6736
+ + + A + +K+LE L K I +L HF +Q E+ R
Sbjct: 225 HVDNLNHAFDVAEKKLEIARLLDAEDVDVTRPDEKSIITYVSLYYHHFAKQKTEMTGARR 284
Query: 6735 EKETY---VTAEDMGMDLEHV--EILQ-----------RKFDDFLKELGNHQYRINEI-- 6610
+ +E M D EH+ E+L R+F + L + + + N+
Sbjct: 285 IANIVGKLMVSETMEDDYEHIASELLNWIRITIKTLESRRFPNSLNGMRDEHAKFNQFRT 344
Query: 6609 NQAADKLVEEGHSE--HDQIYKKRD----------------DVNDAWHRLNTLAATRKEG 6484
++ K E+G E I KR D+ AW +L+ R+
Sbjct: 345 SEKPPKYKEKGELEALFFTIQTKRKAMSRKQYQPPQGLFMHDIESAWAQLDYAENERQVS 404
Query: 6483 LFGAHQ--------VQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTER 6328
+ Q QRF++ A +W+ + L ++GR + V+ +K +
Sbjct: 405 IIAELQRQEKLEQLAQRFHKKAKLRDSWLKSVQVVLEEMEHGRSASQVEKTLKKQQAIST 464
Query: 6327 DLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQ 6148
D+ A E + L ++L +E I + W L + RK L
Sbjct: 465 DILAREDRFKMLTAMCNELCTEKYHESEKIRGMEREIIDRWTQLLALLEQRKRALMSLND 524
Query: 6147 LHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTAS 5968
L L D L + + ++ + ++ K + G E LL H +I+A ++ +
Sbjct: 525 LMSLLRDIDTLSNELYSLEPAVRNRDVGKHLIGVEDLLGKHDLVDAQINAHGSLLSKLSQ 584
Query: 5967 AGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETW 5788
A + + +Q KL+++ + ++L+ L RR+ E+ L F +D E+ W
Sbjct: 585 AANNYIRHKEEQFDVLQRKLDEVTSQYNTLVELCRSRRLALERARSLFQFIQDHEEEMAW 644
Query: 5787 MNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQ-GQHYAA 5611
+ ++E + +V +++ E + + + +L+Q GQ +
Sbjct: 645 LAEKEKLCTTALNSGDISAVPQTTLLYKNVEMEMQTHWARSKGMIAGGERLVQSGQ--SK 702
Query: 5610 DDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTAR-DDS 5434
+D+ GN L E+ Q + +D +E SWI EK+ + DD
Sbjct: 703 EDIQRRLTQMNQGWERLRVAVDALGNWLSEARHAQQYFQDVNEAESWIREKMPLVKSDDL 762
Query: 5433 YLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLW 5254
D LQ+H E+E++A +N + + Q+ +S A +++ +
Sbjct: 763 GRDEGAAESLLQRHARLEEEIRAYKNDITRLEEMQSQLANSAFHTAT-TSQSVQETEEVT 821
Query: 5253 NELVDATNK-KGAKLREAGNEQQFNRNIEDVEAWLS----ELEGQVASEDY-----GKDL 5104
++ K +G +R A E E W + EG V + +Y G+ +
Sbjct: 822 VPQIEMAYKYEGNGMRVAKGEVLALLEKSTPEWWRALKRDGTEGYVPA-NYCKVVPGESV 880
Query: 5103 VSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALR 4924
Q QK +E + + V+ +Q + Y LR
Sbjct: 881 TVTQTTQKTTTTVEGN----------------------ETKSSVVAERQHKISNDYRELR 918
Query: 4923 DPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALI 4744
+ R+R L ++ + + +R+ +D W + +A + V +K L
Sbjct: 919 RLADVRRRLLSDNIKLLRFYRECDDFERWKEIEVSLADEPSPEH----VTAFRRKFDKLE 974
Query: 4743 AEI-ANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDS 4567
A++ N +Q++ ++ AND+I +GH + +I ++ ++ W L+ ++R L+ +
Sbjct: 975 ADMKTNGGTQLKHINDIANDLISEGHGQSRQIENRQHKINAMWENLERLRKQRAVRLEAT 1034
Query: 4566 LQAHQYLSDANEADAWMSEK-EPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIED 4390
+ + + A WM K E + + + K + E LK ++ LE ++
Sbjct: 1035 ERVADFDTTCESAREWMLGKFEQLDRNPNDVKSLQNLERDLKPLEDKIAALEKLAAAVKK 1094
Query: 4389 --------LRKQASQCKYQEQPMGQLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASN 4234
+ ++ ++ + + + ++ +L Q K E +++ D+++ + +
Sbjct: 1095 DHPEEAAAIERKIAELRTLHADLLRRAQEKMLLAEQSQGKEMFESALR--DMMSWIEKTR 1152
Query: 4233 R----DWWKVEVNDRQGFVPAAYV--------------------KRIEPGTAQQHAQQQV 4126
+ D V+V + + + Y + +E ++Q+
Sbjct: 1153 KGMMEDVHPVDVAEAEELLKKHYELGEQIKDKKYEVEYCQELGRRLLERSPRMPKVEEQL 1212
Query: 4125 NSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEI 3946
++ + + + D Y+R R L++ RE+ + K EA +
Sbjct: 1213 QALVSEMAALRDLYRR-------RDTILKQQLDLQLFNRESERIDAATKGHEAFLEFDNL 1265
Query: 3945 GTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNAR 3766
G +E VE L K+ D + L A E RL+ ++ A + ++A I Q+ D+ AR
Sbjct: 1266 GDSVESVENLLKRHRDLEAKLDAQEARLEAFSRTADDMIKAQHADSAY-IEQRRRDVLAR 1324
Query: 3765 WRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDS-EDFGRDLRSVQALQR 3589
A+ QL ++ E Q R+ DE W+ EK + S +D ++
Sbjct: 1325 REAVRRAAAQRKKQLEASLEYQEMRREADEVMGWMHEKAKLVASGDDAALAPSAIPHRLL 1384
Query: 3588 KHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKE 3409
KHE E ++ A +I+ ++ + + L + + + + R++N QW L + N+ +
Sbjct: 1385 KHEAFEAEIIANESRIQQINREGDNLVGKNHYESPNVEKVVRQVNAQWGDLKKQVYNKGQ 1444
Query: 3408 KLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAA 3229
+L + D + D + M ++S++ D+ + LL++H E+
Sbjct: 1445 RLRQAADQKGLDRILEDAHAKLDEMESALNSKDQGLDLRSVKDLLQKHTVLEQEMGLYGN 1504
Query: 3228 TFQAFDQFGNQLLNSHHYAA-------GDIENR---LQGVNEARKG-LEDAWVARRNILD 3082
+ G ++ HY A GD+ R ++G + RKG L+++ + + + D
Sbjct: 1505 KLADIENRGKKMAVEGHYDADKIHMTVGDLLKRYAAMKGPAQRRKGDLDESRLWHQLVFD 1564
Query: 3081 QCLELQLFYRDCEQADTWMSAREAFLAQEDPSGDNVESL--IKKHEDFDKAINTQEEKIK 2908
ELQ W++ ++ + +D E+L +KK E + +N +I
Sbjct: 1565 VDCELQ-----------WIAEKKPIASSQDCGRTLTEALNMVKKQEQLEAEVNQHGGQID 1613
Query: 2907 GLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADE 2728
+ A L+K +H S + K ++ W+ L+ L +R + QQ+ DA E
Sbjct: 1614 KVLGQASKLVKRHHPASSQIKAKSGELESAWSELRRLLRSRRAIVDWGVKEQQYLFDAAE 1673
Query: 2727 IENWMTEKFQIAQEENYRDPTNIQQK-HQKQQAFEAELHANSDRIAAIIQAGNNLIENAK 2551
+E+WM EK E+Y + + +K K +A ++ + + + L+++ +
Sbjct: 1674 VESWMNEKRNALASEDYGNDEDAARKLLAKHRALCEDMTTYRQWLEKLDVKCSELVQSDR 1733
Query: 2550 CGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILL 2371
R L ++D L K ++ L++A +M DLE W+GE
Sbjct: 1734 --PHVDRFQKRQDELVHEFDSLSKLAEDRRNALEDAVCLYEYMRESADLEQWIGEQLQTA 1791
Query: 2370 QSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKL 2191
ED+ +D ++ L K + + +R A+++L + + + ++++
Sbjct: 1792 LCEDFAEDYEHLKELQSKFDEFKQSVKTGSERFTSCETAANTILRRNPPFARDVVKKQEK 1851
Query: 2190 IADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQN 2011
+ ++ + + R KL+ A +H+F RD+D+ E W+ + K+ D GRD+ V +
Sbjct: 1852 LRSAWNLLCEYIETRTAKLAVAEELHRFHRDVDEFEQWMAD-KMANMPRDLGRDVKHVHS 1910
Query: 2010 LRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDL 1831
L ++H +D E +H Q L KL E A G +QI R + L + W ++R+
Sbjct: 1911 LWQQHEALDKE--THNAQPRLTKLVEEAERLKKAYPGGNAEQIGGRQQTLVEEWEELRNA 1968
Query: 1830 TGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVD 1651
T +R L + F G V + AW + + SD ++ + L +H +
Sbjct: 1969 TDDRKDMLRAAFDLHTFNGKVRDLLAWTDLTISDIQSDLQINDLQQAEWLQTEHSRLSHE 2028
Query: 1650 LELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAY 1471
++ + L++ G+ +++ ++ IK + L+ L + S R L +
Sbjct: 2029 MDAREPEFTRLVSDGEKMVNAQHYATEEIKNKTRLLKTALERLRSEWTLRNGYLSQAVQW 2088
Query: 1470 LQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITE 1291
F + + + I K +RS G ++ V+ + + F+ L+ + E +
Sbjct: 2089 HAFQREAKQIIASIGSKRTTLRSLAVGGSVADVESQKKRLDTFEKALSTLD-ERTATLDH 2147
Query: 1290 LKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAK 1111
++LV S H +S I + V + + L EAR +F
Sbjct: 2148 TANELVKSRHMESKNIAMWQSKVHEELKLLREDIEARHVMLKDAFALA--------SFGS 2199
Query: 1110 KASTFNSWFE-------NAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQ 952
+ +W + A + ++ + S+EE H + +++ + Q+
Sbjct: 2200 DVAQIEAWIDEKTNGIRKARDQSSESI---SIEEKMKRLQTHQALEAEVAANKTIVDQIL 2256
Query: 951 DLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFA 772
+++KS + N T + L W L ++ + L +E D LR F
Sbjct: 2257 HRGQQLKSLH--RNSKIGDTCNELNVKWSQLAGACDDQSRAL------EEARDLLR--FK 2306
Query: 771 KLANAFHAWL--------TNTRQEMMEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEK 619
+L W+ T ME L E+LD + + ++ ++ EK
Sbjct: 2307 QLVENVLTWINEKEVLVSTADMGRDMEHCRMLLERLDGTRSDSTVDEQTLDEINRLGEK 2365
Score = 174 bits (442), Expect = 2e-41
Identities = 263/1345 (19%), Positives = 518/1345 (37%), Gaps = 38/1345 (2%)
Frame = -1
Query: 4284 EVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIEPGTAQQHAQQQVNSIGGKQ 4105
+V+ KK ++ LL+A + D + + +V Y + T A++ N +G
Sbjct: 234 DVAEKKLEIARLLDAEDVDVTRPDEKSIITYVSLYYHHFAKQKTEMTGARRIANIVGK-- 291
Query: 4104 SEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQV 3925
+M+ ET + E A++L WI+ + L +
Sbjct: 292 ----------LMVSETMEDDYEHI---------ASELLNWIRITIKTLESRRFPNSLNGM 332
Query: 3924 EVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIE--------DLNA 3769
KF+ F+ K + + E ++ ++ QT+ R+Q + D+ +
Sbjct: 333 RDEHAKFNQFRTSEKPPKYK--EKGELEALFFTI-QTKRKAMSRKQYQPPQGLFMHDIES 389
Query: 3768 RWRALXXXXXXXXXQLGSAHE--------VQRFHRDVDETRDWIQEKDDALDSEDFGRDL 3613
W L + + + QRFH+ W++ L+ + GR
Sbjct: 390 AWAQLDYAENERQVSIIAELQRQEKLEQLAQRFHKKAKLRDSWLKSVQVVLEEMEHGRSA 449
Query: 3612 RSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLT 3433
V+ +K + + D+ A D+ K L N L +E+I ++RE+ ++W +L
Sbjct: 450 SQVEKTLKKQQAISTDILAREDRFKMLTAMCNELCTEKYHESEKIRGMEREIIDRWTQLL 509
Query: 3432 SKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYR 3253
+ RK L+ D L D L + S+ V ++++ + G E LL +H
Sbjct: 510 ALLEQRKRALMSLNDLMSLLRDIDTLSNELYSLEPAVRNRDVGKHLIGVEDLLGKHDLVD 569
Query: 3252 TEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCL 3073
+I++ + Q N + ++ +L V L + +RR L++
Sbjct: 570 AQINAHGSLLSKLSQAANNYIRHKEEQFDVLQRKLDEVTSQYNTLVELCRSRRLALERAR 629
Query: 3072 ELQLFYRDCEQADTWMSAREAFLAQEDPSGD--NVESLIKKHEDFDKAINTQEEKIKGLK 2899
L F +D E+ W++ +E SGD V +++ + + T + KG+
Sbjct: 630 SLFQFIQDHEEEMAWLAEKEKLCTTALNSGDISAVPQTTLLYKNVEMEMQTHWARSKGMI 689
Query: 2898 LFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIEN 2719
E L+++ + R+ Q+ W L+ A+ L E++ QQ+ +D +E E+
Sbjct: 690 AGGERLVQSGQ-SKEDIQRRLTQMNQGWERLRVAVDALGNWLSEARHAQQYFQDVNEAES 748
Query: 2718 WMTEKFQIAQEENY-RDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGG 2542
W+ EK + + ++ RD + Q+ E E+ A + I + + + L +A
Sbjct: 749 WIREKMPLVKSDDLGRDEGAAESLLQRHARLEEEIRAYKNDITRLEEMQSQLANSA---- 804
Query: 2541 GEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKD---LEFWLGEVEILL 2371
TT++ +E + MA + + GEV LL
Sbjct: 805 -----------------FHTATTSQSVQETEEVTVPQIEMAYKYEGNGMRVAKGEVLALL 847
Query: 2370 QSEDYGKDLASVENLLKKHSLLEADIVAHQDR--------VGEMNEQADSLLENDQFQGQ 2215
+ K LK+ E + A+ + V + ++ + +E ++ +
Sbjct: 848 E-----KSTPEWWRALKRDG-TEGYVPANYCKVVPGESVTVTQTTQKTTTTVEGNETKSS 901
Query: 2214 QIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYG 2035
+AER+ I++ Y ++++A RR LS + + +F+R+ DD E W K++ VS
Sbjct: 902 VVAERQHKISNDYRELRRLADVRRRLLSDNIKLLRFYRECDDFERW---KEIEVSL---- 954
Query: 2034 RDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGED-QIKKRMEDLE 1858
D P +++ R+ D A + ++ G G+ QI+ R +
Sbjct: 955 ADEPSPEHVTAFRRKFDKLEADMKTNGGTQLKHINDIANDLISEGHGQSRQIENRQHKIN 1014
Query: 1857 QSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLL 1678
W + L R RL+ +E F E WM K + L D ++ +Q L
Sbjct: 1015 AMWENLERLRKQRAVRLEATERVADFDTTCESAREWMLGKFEQL--DRNPNDVKSLQNL- 1071
Query: 1677 KKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRL 1498
+ DL+ + ++A L + + A I+++ +LR ++ A+ ++
Sbjct: 1072 ------ERDLKPLEDKIAALEKLAAAVKKDHPEEAAAIERKIAELRTLHADLLRRAQEKM 1125
Query: 1497 AKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFE 1318
+ F + SWI + + + + D++ + LL K + +
Sbjct: 1126 LLAEQSQGKEMFESALRDMMSWIEKTRKGMMEDVHPVDVAEAEELLKKHYELGEQIKDKK 1185
Query: 1317 HEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQI 1138
+E ++ EL +L+ ++SP + K V ++ Q L++ A R Q
Sbjct: 1186 YE-VEYCQELGRRLL----ERSPRMPK----VEEQLQALVSEMAALRDLYRRRDTILKQQ 1236
Query: 1137 EELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQ 958
+L L F +++ ++ + E L +S+E + L H + + L + E
Sbjct: 1237 LDLQL-FNRESERIDAATKGHEAFLEFDNLGDSVESVENLLKRHRDLEAKLDAQEARLEA 1295
Query: 957 L-QDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRR 781
+ D IK+ + D L ++R +R+++L + QE +RR
Sbjct: 1296 FSRTADDMIKAQHADSAYIEQRRRDVLARR-EAVRRAAAQRKKQLEASLEYQE----MRR 1350
Query: 780 EFAKLANAFH--AWLTNTRQEMMEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAML 607
E ++ H A L + + A + +L E EI AN+ +++QI +G
Sbjct: 1351 EADEVMGWMHEKAKLVASGDDAALAPSAIPHRLLKHEAFEAEIIANESRIQQINREG--- 1407
Query: 606 ERNLILDNRYTEHSTVGIAQ----AWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREF 439
NL+ N Y + + + W L + L Q + + E+A +
Sbjct: 1408 -DNLVGKNHYESPNVEKVVRQVNAQWGDLKKQVYNKGQRLRQAADQKGLDRILEDAHAKL 1466
Query: 438 SMMFKHFDKEKTGRLDHQQFKSCLR 364
M + + G LD + K L+
Sbjct: 1467 DEMESALNSKDQG-LDLRSVKDLLQ 1490
Score = 135 bits (341), Expect = 1e-29
Identities = 148/703 (21%), Positives = 283/703 (40%), Gaps = 13/703 (1%)
Frame = -1
Query: 2427 FMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQAD 2248
F K + WL V+++L+ ++G+ + VE LKK + DI+A +DR + +
Sbjct: 422 FHKKAKLRDSWLKSVQVVLEEMEHGRSASQVEKTLKKQQAISTDILAREDRFKMLTAMCN 481
Query: 2247 SLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKE 2068
L + ++I + I DR+ + + R+ L ++ RDID + +
Sbjct: 482 ELCTEKYHESEKIRGMEREIIDRWTQLLALLEQRKRALMSLNDLMSLLRDIDTLSNELYS 541
Query: 2067 KKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGED 1888
+ V + D G+ L GV++L KH +D ++ +H +S + +R E D
Sbjct: 542 LEPAVRNRDVGKHLIGVEDLLGKHDLVDAQINAHGSLLSKLSQAANNYIRHKEEQ---FD 598
Query: 1887 QIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFG 1708
++++++++ + + +L +R L+ + + F+ D EEE AW+ EK+++ +
Sbjct: 599 VLQRKLDEVTSQYNTLVELCRSRRLALERARSLFQFIQDHEEEMAWLAEKEKLCTTALNS 658
Query: 1707 ENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLI 1528
+++ V + +++++ H R +I G+ L+ +G I++R Q+
Sbjct: 659 GDISAVPQTTLLYKNVEMEMQTHWARSKGMIAGGERLVQSG-QSKEDIQRRLTQMNQGWE 717
Query: 1527 EIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQE 1348
+ + L + Q+ + ESWI EK V+S+D GRD + + LL +
Sbjct: 718 RLRVAVDALGNWLSEARHAQQYFQDVNEAESWIREKMPLVKSDDLGRDEGAAESLLQRHA 777
Query: 1347 AFDAGLNAFEHEGIQRITELKDQLVSSE-HQQSPAIEKRHTNVIQRWQNLLAHSEARRXX 1171
+ + A++++ I R+ E++ QL +S H + + + T + Q +A+
Sbjct: 778 RLEEEIRAYKND-ITRLEEMQSQLANSAFHTATTSQSVQETEEVTVPQIEMAYKYEGNGM 836
Query: 1170 XXXXXXXXXQIEELYLAF--AKKASTFNSWF----------ENAEEDLTDPVRCNSLEEI 1027
+E+ + A K + E+ T ++E
Sbjct: 837 RVAKGEVLALLEKSTPEWWRALKRDGTEGYVPANYCKVVPGESVTVTQTTQKTTTTVEGN 896
Query: 1026 RALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRII 847
E Q +S+ + R+L D+ RR+ S N+ + + D E W
Sbjct: 897 ETKSSVVAERQHKISNDYRELRRLADVRRRLLSDNIKLLRF-YRECDDFE-RW------- 947
Query: 846 KEREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEMMEAGGTLEEQLDAVERKA 667
KE E LA E E RR+F KL +M GGT + ++ +
Sbjct: 948 KEIEVSLADE-PSPEHVTAFRRKFDKL-----------EADMKTNGGTQLKHINDIANDL 995
Query: 666 KEIKANKGQLRQIEEKGAMLERNLILDNRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQI 487
I GQ RQIE + +H I W+ L++L + LE
Sbjct: 996 --ISEGHGQSRQIENR---------------QHK---INAMWENLERLRKQRAVRLEATE 1035
Query: 486 QARNQSGVSEEALREFSMMFKHFDKEKTGRLDHQQFKSCLRAL 358
+ + E A F+ D+ Q + L+ L
Sbjct: 1036 RVADFDTTCESAREWMLGKFEQLDRNPNDVKSLQNLERDLKPL 1078
>gi|38074605|ref|XP_355324.1| similar to Spectrin alpha chain, brain
(Spectrin, non-erythroid alpha chain) (Alpha-II spectrin)
(Fodrin alpha chain) [Mus musculus]
Length = 613
Score = 652 bits (1682), Expect = 0.0
Identities = 329/596 (55%), Positives = 422/596 (70%)
Frame = -1
Query: 7218 IRILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQ 7039
+++LETA+DI +RRQ+VL Y FK+ S +R +LE++ +FQ+F+RDA+EL WI EKLQ
Sbjct: 6 VKVLETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQ 65
Query: 7038 TAQEENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLE 6859
A +EN++DP+NLQ K+QKH+AFEAEVQA++ I LD+TGN MI HFASE I+ RL
Sbjct: 66 VASDENYKDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLM 125
Query: 6858 ELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVE 6679
ELH W KGIKL QA KL+ ++R+C++++ WI +KE VT+E++G DLEHVE
Sbjct: 126 ELHRQWELLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVE 185
Query: 6678 ILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAA 6499
+LQ+KF++F +L H+ R+NE++Q A KL++E H E + I K+D+VN AW RL LA
Sbjct: 186 VLQKKFEEFQTDLAAHEERVNEVSQFAAKLIQEQHPEEELIKTKQDEVNAAWQRLKGLAL 245
Query: 6498 TRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLA 6319
R+ LFGA +VQRFNRD DET+ WI EK+ ++SDD+GRDL +VQAL RKHEG ERDLA
Sbjct: 246 QRQGKLFGAAEVQRFNRDVDETIGWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLA 305
Query: 6318 ALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHR 6139
ALE K+ L EA +L ++HP A I K ++ W ++ A R L+ S++L R
Sbjct: 306 ALEDKVKALCAEADRLQQSHPLSASQIQVKREELITNWEQIRTLAAERHARLDDSYRLQR 365
Query: 6138 FLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQ 5959
FLAD+RDL SW+ +MKA+I ADELA DVAGAEALL+ HQEHKGEIDA DSF +GQ
Sbjct: 366 FLADFRDLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQ 425
Query: 5958 KLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNK 5779
L+ S EV+EKL L E+++LL LWE RR YEQCMDLQLFYRDTEQ + WM+K
Sbjct: 426 ALLAASHYASDEVREKLSILSEERTALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSK 485
Query: 5778 QEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVA 5599
QEAFL N DLGDSLDSVE L+KKHEDFEKSL+AQEEKI ALDEFATKLIQ HYA +DVA
Sbjct: 486 QEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMEDVA 545
Query: 5598 EXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSY 5431
R L +S+ Q F RD DE+ SW+ EK+ TA D++Y
Sbjct: 546 TRRDALLSRRNALHERAMHRRAQLADSFHLQQFFRDSDELKSWVNEKMKTATDEAY 601
Score = 432 bits (1110), Expect = e-119
Identities = 225/478 (47%), Positives = 318/478 (66%), Gaps = 2/478 (0%)
Frame = -1
Query: 4101 EIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVE 3922
E+ +++ L+ + KL +A K Q LRE D+ +WI +EA+ +E+G DLE VE
Sbjct: 126 ELHRQWELLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVE 185
Query: 3921 VLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXX 3742
VLQKKF++F+ DL A+E R+ E++Q A L E + I+ + +++NA W+ L
Sbjct: 186 VLQKKFEEFQTDLAAHEERVNEVSQFAAKLIQEQHPEEEL-IKTKQDEVNAAWQRLKGLA 244
Query: 3741 XXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDL 3562
+L A EVQRF+RDVDET WI+EK+ + S+DFGRDL SVQAL RKHEG+ERDL
Sbjct: 245 LQRQGKLFGAAEVQRFNRDVDETIGWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDL 304
Query: 3561 AALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQ 3382
AAL DK+K+L +A+RL+QSHP +A QI + EL W ++ + A R +L DSY Q
Sbjct: 305 AALEDKVKALCAEADRLQQSHPLSASQIQVKREELITNWEQIRTLAAERHARLDDSYRLQ 364
Query: 3381 RFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFG 3202
RFL+D+RDL W+ M L+++ ELANDV GAEALL+RHQE++ EID+ +F++ D+ G
Sbjct: 365 RFLADFRDLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDAHEDSFKSADESG 424
Query: 3201 NQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMS 3022
LL + HYA+ ++ +L ++E R L + W RR +QC++LQLFYRD EQ D WMS
Sbjct: 425 QALLAASHYASDEVREKLSILSEERTALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMS 484
Query: 3021 AREAFLAQED--PSGDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAV 2848
+EAFL ED S D+VE+L+KKHEDF+K+++ QEEKI L FA LI+NNHY V
Sbjct: 485 KQEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMEDV 544
Query: 2847 TRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYR 2674
+RD +L R N L E + +R +L +S LQQF RD+DE+++W+ EK + A +E Y+
Sbjct: 545 ATRRDALLSRRNALHERAMHRRAQLADSFHLQQFFRDSDELKSWVNEKMKTATDEAYK 602
Score = 318 bits (814), Expect = 2e-84
Identities = 180/562 (32%), Positives = 307/562 (54%), Gaps = 4/562 (0%)
Frame = -1
Query: 2850 VTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRD 2671
+ +R Q+LDR++ KE +R KL +S Q F RDA+E+E W+ EK Q+A +ENY+D
Sbjct: 15 IQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQVASDENYKD 74
Query: 2670 PTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWD 2491
PTN+Q K QK QAFEAE+ ANS I + + GN +I + RL L+ QW+
Sbjct: 75 PTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFAS--ETIRTRLMELHRQWE 132
Query: 2490 LLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHS 2311
LL++ EK +L +A K ++ +D+ W+ + E ++ SE+ G+DL VE L KK
Sbjct: 133 LLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQKKFE 192
Query: 2310 LLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLS 2131
+ D+ AH++RV E+++ A L++ + + I ++ + + +K +A R+ KL
Sbjct: 193 EFQTDLAAHEERVNEVSQFAAKLIQEQHPEEELIKTKQDEVNAAWQRLKGLALQRQGKLF 252
Query: 2130 KALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVS 1951
A V +F RD+D+ WIKEK+ L++SDD+GRDL VQ L RKH ++ +LA+ E +V
Sbjct: 253 GAAEVQRFNRDVDETIGWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLAALEDKVK 312
Query: 1950 LVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGD 1771
+ + + L +S + QI+ + E+L +W QIR L RH RLD+S Q FL D
Sbjct: 313 ALCAEADRLQQSHP---LSASQIQVKREELITNWEQIRTLAAERHARLDDSYRLQRFLAD 369
Query: 1770 VEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIH 1591
+ +W+ E + ++ +D ++AG + LL +H + +++ H+ G L+
Sbjct: 370 FRDLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQALLA 429
Query: 1590 NGNHHAPHIKQRCDQL---RARLIEIESMAEGRLAKLRDNSAYLQFMWK-CDVVESWIAE 1423
++ + ++++ L R L+E+ + + + D LQ ++ + V++W+++
Sbjct: 430 ASHYASDEVREKLSILSEERTALLELWELRRQQYEQCMD----LQLFYRDTEQVDNWMSK 485
Query: 1422 KEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAI 1243
+E + +ED G L SV+ LL K E F+ L+A + E I + E +L+ + H +
Sbjct: 486 QEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSA-QEEKITALDEFATKLIQNNHYAMEDV 544
Query: 1242 EKRHTNVIQRWQNLLAHSEARR 1177
R ++ R L + RR
Sbjct: 545 ATRRDALLSRRNALHERAMHRR 566
Score = 263 bits (673), Expect = 4e-68
Identities = 185/631 (29%), Positives = 312/631 (49%), Gaps = 5/631 (0%)
Frame = -1
Query: 5529 LKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRL 5350
L++SY+ Q F RD +E+ WI EKL A D++Y DPTN++GKLQKH FE E++AN +
Sbjct: 40 LEDSYRFQFFQRDAEELEKWIQEKLQVASDENYKDPTNLQGKLQKHQAFEAEVQANSGAI 99
Query: 5349 DDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIE 5170
+ TG +I GHFA++ I RL +++ W L++ +KG KL +A Q+ R E
Sbjct: 100 VKLDETGNLMISEGHFASETIRTRLMELHRQWELLLEKMREKGIKLLQAQKLVQYLRECE 159
Query: 5169 DVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEE 4990
DV W+++ E V SE+ G+DL V+ LQKK ++D AH +RV+ + Q A + +E+
Sbjct: 160 DVMDWINDKEAIVTSEELGQDLEHVEVLQKKFEEFQTDLAAHEERVNEVSQFAAKLIQEQ 219
Query: 4989 HFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAG 4810
H +I KQ+ + + L+ +R+ KL + + + RD+++ + WI+EKEQ+
Sbjct: 220 HPEEELIKTKQDEVNAAWQRLKGLALQRQGKLFGAAEVQRFNRDVDETIGWIKEKEQLMA 279
Query: 4809 STNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFL-APEIRDKLAQ 4633
S + GRDL VQ L++K + L ++A + +++++ + A D +QQ H L A +I+ K +
Sbjct: 280 SDDFGRDLASVQALLRKHEGLERDLAALEDKVKALCAEA-DRLQQSHPLSASQIQVKREE 338
Query: 4632 LRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEA 4453
L NW +++ A +R LDDS + ++L+D + +W++E + ++ + + D AEA
Sbjct: 339 LITNWEQIRTLAAERHARLDDSYRLQRFLADFRDLTSWVTEMKALINADELANDVAGAEA 398
Query: 4452 LLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQPMGQLGRDCVLALYDYQEKSPREVSM 4273
LL +H+ +++A ED K A + GQ +LA Y RE
Sbjct: 399 LLDRHQEHKGEIDAH----EDSFKSADE-------SGQ----ALLAASHYASDEVRE--- 440
Query: 4272 KKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIEPGTAQQHAQQQVNSIGGKQSEIE 4093
K +L+ + + W++ QQ+ Q + + +E
Sbjct: 441 -KLSILSEERTALLELWELR--------------------RQQYEQCMDLQLFYRDTEQV 479
Query: 4092 DKY---QRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVE 3922
D + Q +L E DL + + S EA
Sbjct: 480 DNWMSKQEAFLLNE--------------------DLGDSLDSVEA--------------- 504
Query: 3921 VLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVR-IRQQIEDLNARWRALXXX 3745
L KK +DF+ L A E ++ +++ AT L + A+ + + + L +R AL
Sbjct: 505 -LLKKHEDFEKSLSAQEEKITALDEFATKL--IQNNHYAMEDVATRRDALLSRRNALHER 561
Query: 3744 XXXXXXQLGSAHEVQRFHRDVDETRDWIQEK 3652
QL + +Q+F RD DE + W+ EK
Sbjct: 562 AMHRRAQLADSFHLQQFFRDSDELKSWVNEK 592
Score = 252 bits (644), Expect = 8e-65
Identities = 154/595 (25%), Positives = 295/595 (48%), Gaps = 3/595 (0%)
Frame = -1
Query: 3813 ETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDS 3634
ETA I+++ + + R+ +L ++ Q F RD +E WIQEK
Sbjct: 10 ETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQVASD 69
Query: 3633 EDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELN 3454
E++ +D ++Q +KH+ E ++ A I LDE N + A+E I EL+
Sbjct: 70 ENY-KDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLMELH 128
Query: 3453 EQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALL 3274
QW L K + KLL + ++L + D+M WI +V+S+EL D+ E L
Sbjct: 129 RQWELLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQ 188
Query: 3273 ERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARR 3094
++ +E++T++ + QF +L+ H I+ + VN A + L+ + R+
Sbjct: 189 KKFEEFQTDLAAHEERVNEVSQFAAKLIQEQHPEEELIKTKQDEVNAAWQRLKGLALQRQ 248
Query: 3093 NILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGD--NVESLIKKHEDFDKAINTQE 2920
L E+Q F RD ++ W+ +E +A +D D +V++L++KHE ++ + E
Sbjct: 249 GKLFGAAEVQRFNRDVDETIGWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLAALE 308
Query: 2919 EKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSR 2740
+K+K L A+ L +++ + + KR++++ W ++ ++ +L +S LQ+F
Sbjct: 309 DKVKALCAEADRLQQSHPLSASQIQVKREELITNWEQIRTLAAERHARLDDSYRLQRFLA 368
Query: 2739 DADEIENWMTE-KFQIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLI 2563
D ++ +W+TE K I +E D + + Q + E+ A+ D + ++G L+
Sbjct: 369 DFRDLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQALL 428
Query: 2562 ENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEV 2383
+ E V +L L+++ L++ + + ++ + F + ++ W+ +
Sbjct: 429 AASHYASDE--VREKLSILSEERTALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQ 486
Query: 2382 EILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAE 2203
E L +ED G L SVE LLKKH E + A ++++ ++E A L++N+ + + +A
Sbjct: 487 EAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMEDVAT 546
Query: 2202 RRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDY 2038
RR + R + + + A RR +L+ + ++ QFFRD D+ +SW+ EK + + Y
Sbjct: 547 RRDALLSRRNALHERAMHRRAQLADSFHLQQFFRDSDELKSWVNEKMKTATDEAY 601
Score = 251 bits (641), Expect = 2e-64
Identities = 152/585 (25%), Positives = 293/585 (49%), Gaps = 1/585 (0%)
Frame = -1
Query: 6564 DQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDY 6385
+ I ++R V D +HR L+ R++ L +++ Q F RDA+E WI EK L ++SD+
Sbjct: 13 EDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEK-LQVASDEN 71
Query: 6384 GRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAW 6205
+D N+Q +KH+ E ++ A G +++L++ + + +E I + + W
Sbjct: 72 YKDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLMELHRQW 131
Query: 6204 NALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESH 6025
L EK + + L ++ +L ++L + D++ WI D +A++ ++EL +D+ E L +
Sbjct: 132 ELLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQKKF 191
Query: 6024 QEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILY 5845
+E + ++ A + N+ + KL++ PE ++ K ++++ L GL +R+
Sbjct: 192 EEFQTDLAAHEERVNEVSQFAAKLIQEQHPEEELIKTKQDEVNAAWQRLKGLALQRQGKL 251
Query: 5844 EQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKI 5665
++Q F RD ++ W+ ++E +A+ D G L SV+ L++KHE E+ LAA E+K+
Sbjct: 252 FGAAEVQRFNRDVDETIGWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLAALEDKV 311
Query: 5664 NALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCD 5485
AL A +L Q +A + R L +SY+ Q F D
Sbjct: 312 KALCAEADRLQQSHPLSASQIQVKREELITNWEQIRTLAAERHARLDDSYRLQRFLADFR 371
Query: 5484 EMVSWITE-KLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSG 5308
++ SW+TE K D+ D L +H + E+ A+E+ +G+ ++ +
Sbjct: 372 DLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQALLAAS 431
Query: 5307 HFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVA 5128
H+A+D + ++L ++ L++ + + + + Q F R+ E V+ W+S+ E +
Sbjct: 432 HYASDEVREKLSILSEERTALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLL 491
Query: 5127 SEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENL 4948
+ED G L SV+ L KK E +A +++ + + A + + H+ + +++ L
Sbjct: 492 NEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMEDVATRRDAL 551
Query: 4947 QQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVA 4813
R NAL + R+ +L +S Q FRD ++ +W+ EK + A
Sbjct: 552 LSRRNALHERAMHRRAQLADSFHLQQFFRDSDELKSWVNEKMKTA 596
Score = 248 bits (634), Expect = 1e-63
Identities = 152/597 (25%), Positives = 295/597 (48%), Gaps = 4/597 (0%)
Frame = -1
Query: 3171 AGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQE- 2995
A DI+ R Q V + ++ RR L+ Q F RD E+ + W+ + + E
Sbjct: 12 AEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQVASDEN 71
Query: 2994 --DPSGDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILD 2821
DP+ N++ ++KH+ F+ + I L +I H+ S + + ++
Sbjct: 72 YKDPT--NLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLMELHR 129
Query: 2820 RWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIA-QEENYRDPTNIQQKHQ 2644
+W L E + +K KL ++Q L Q+ R+ +++ +W+ +K I EE +D +++ +
Sbjct: 130 QWELLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQK 189
Query: 2643 KQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEK 2464
K + F+ +L A+ +R+ + Q LI+ E + + +N W L ++
Sbjct: 190 KFEEFQTDLAAHEERVNEVSQFAAKLIQEQH--PEEELIKTKQDEVNAAWQRLKGLALQR 247
Query: 2463 SYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAH 2284
+L A + + F V + W+ E E L+ S+D+G+DLASV+ LL+KH LE D+ A
Sbjct: 248 QGKLFGAAEVQRFNRDVDETIGWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLAAL 307
Query: 2283 QDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFF 2104
+D+V + +AD L ++ QI +R+ + ++ ++ +A +R +L + + +F
Sbjct: 308 EDKVKALCAEADRLQQSHPLSASQIQVKREELITNWEQIRTLAAERHARLDDSYRLQRFL 367
Query: 2103 RDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEEL 1924
D D SW+ E K L+++D+ D+ G + L +H+ E+ +HE G+ L
Sbjct: 368 ADFRDLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQAL 427
Query: 1923 LRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMN 1744
L ++ A D++++++ L + + +L R Q+ ++ Q F D E+ + WM+
Sbjct: 428 LAASHYAS---DEVREKLSILSEERTALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMS 484
Query: 1743 EKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHI 1564
+++ L +++ G+++ V+ LLKKH+ F+ L ++++ L LI N ++ +
Sbjct: 485 KQEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMEDV 544
Query: 1563 KQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDF 1393
R D L +R + A R A+L D+ QF D ++SW+ EK + E +
Sbjct: 545 ATRRDALLSRRNALHERAMHRRAQLADSFHLQQFFRDSDELKSWVNEKMKTATDEAY 601
Score = 221 bits (562), Expect = 3e-55
Identities = 142/584 (24%), Positives = 270/584 (45%), Gaps = 1/584 (0%)
Frame = -1
Query: 6255 DRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGA 6076
+ AE I ++ ++ KE + R+ LE S++ F D +L WI + K + +
Sbjct: 10 ETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQE-KLQVAS 68
Query: 6075 DELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLD 5896
DE KD + L+ HQ + E+ A + + + G ++ G S ++ +L +L
Sbjct: 69 DENYKDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLMELH 128
Query: 5895 HEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLI 5716
+ LL E+ I Q L + R+ E W+N +EA + + +LG L+ VE L
Sbjct: 129 RQWELLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQ 188
Query: 5715 KKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRG 5536
KK E+F+ LAA EE++N + +FA KLIQ QH + + R
Sbjct: 189 KKFEEFQTDLAAHEERVNEVSQFAAKLIQEQHPEEELIKTKQDEVNAAWQRLKGLALQRQ 248
Query: 5535 NALKESYKRQTFDRDCDEMVSWITEKLST-ARDDSYLDPTNIRGKLQKHINFEQELKANE 5359
L + + Q F+RD DE + WI EK A DD D +++ L+KH E++L A E
Sbjct: 249 GKLFGAAEVQRFNRDVDETIGWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLAALE 308
Query: 5358 NRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNR 5179
+++ + + +++ S +A I + ++ W ++ ++ A+L ++ Q+F
Sbjct: 309 DKVKALCAEADRLQQSHPLSASQIQVKREELITNWEQIRTLAAERHARLDDSYRLQRFLA 368
Query: 5178 NIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQ 4999
+ D+ +W++E++ + +++ D+ + L + + + +AH D + Q
Sbjct: 369 DFRDLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQALL 428
Query: 4998 EEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQ 4819
H+ + + K L + AL + E R+++ + +RD E W+ ++E
Sbjct: 429 AASHYASDEVREKLSILSEERTALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEA 488
Query: 4818 VAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKL 4639
+ + G L V+ L+KK + ++ + +I ++ A +IQ H+ ++ +
Sbjct: 489 FLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMEDVATRR 548
Query: 4638 AQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEK 4507
L L +A RR L DS Q+ D++E +W++EK
Sbjct: 549 DALLSRRNALHERAMHRRAQLADSFHLQQFFRDSDELKSWVNEK 592
Score = 214 bits (545), Expect = 3e-53
Identities = 137/593 (23%), Positives = 289/593 (48%), Gaps = 3/593 (0%)
Frame = -1
Query: 6885 SEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAED 6706
+E I++R +++ + + KL+ + + F R +E+ WI+EK V +++
Sbjct: 12 AEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEK-LQVASDE 70
Query: 6705 MGMDLEHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDA 6526
D +++ +K F E+ + I ++++ + ++ EGH + I + +++
Sbjct: 71 NYKDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLMELHRQ 130
Query: 6525 WHRLNTLAATRKEG--LFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQ 6352
W L L R++G L A ++ ++ R+ ++ + WI +K+ ++S++ G+DL +V+ LQ
Sbjct: 131 WELL--LEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQ 188
Query: 6351 RKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRK 6172
+K E + DLAA E ++ ++ + A KL + E I K D+ AAW LK A R+
Sbjct: 189 KKFEEFQTDLAAHEERVNEVSQFAAKLIQEQHPEEELIKTKQDEVNAAWQRLKGLALQRQ 248
Query: 6171 DGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARA 5992
L + ++ RF D + I WI + + ++ +D+ +D+A +ALL H+ + ++ A
Sbjct: 249 GKLFGAAEVQRFNRDVDETIGWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLAALE 308
Query: 5991 DSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYR 5812
D + +L + + ++Q K E+L + L ER + LQ F
Sbjct: 309 DKVKALCAEADRLQQSHPLSASQIQVKREELITNWEQIRTLAAERHARLDDSYRLQRFLA 368
Query: 5811 DTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLI 5632
D +W+ + +A + +L + + E L+ +H++ + + A E+ + DE L+
Sbjct: 369 DFRDLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQALL 428
Query: 5631 QGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLS 5452
HYA+D+V E R ++ Q F RD +++ +W++++ +
Sbjct: 429 AASHYASDEVREKLSILSEERTALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEA 488
Query: 5451 TARDDSYLDPTN-IRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRL 5275
++ D + + L+KH +FE+ L A E ++ + ++I + H+A + + R
Sbjct: 489 FLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMEDVATRR 548
Query: 5274 RQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDY 5116
+ + N L + + A+L ++ + QQF R+ +++++W++E E Y
Sbjct: 549 DALLSRRNALHERAMHRRAQLADSFHLQQFFRDSDELKSWVNEKMKTATDEAY 601
Score = 211 bits (537), Expect = 2e-52
Identities = 141/587 (24%), Positives = 283/587 (48%), Gaps = 4/587 (0%)
Frame = -1
Query: 4134 QQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQ 3955
+ I ++ ++ D+Y R L R++KLE++ + R+A +L +WI+ + VA+
Sbjct: 10 ETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQVASD 69
Query: 3954 QEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDL 3775
+ D ++ +K F+ +++AN + ++++ + S G + IR ++ +L
Sbjct: 70 ENY-KDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASET-IRTRLMEL 127
Query: 3774 NARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQAL 3595
+ +W L +L A ++ ++ R+ ++ DWI +K+ + SE+ G+DL V+ L
Sbjct: 128 HRQWELLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVEVL 187
Query: 3594 QRKHEGVERDLAALGDKIKSLDEKANRL-RQSHPEAAEQIYDLQRELNEQWNRLTSKANN 3418
Q+K E + DLAA +++ + + A +L ++ HPE E I Q E+N W RL A
Sbjct: 188 QKKFEEFQTDLAAHEERVNEVSQFAAKLIQEQHPE-EELIKTKQDEVNAAWQRLKGLALQ 246
Query: 3417 RKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDS 3238
R+ KL + + QRF D + + WI QL++S + D+ +ALL +H+ ++ +
Sbjct: 247 RQGKLFGAAEVQRFNRDVDETIGWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLAA 306
Query: 3237 RAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLF 3058
+A ++L SH +A I+ + + + + + R LD LQ F
Sbjct: 307 LEDKVKALCAEADRLQQSHPLSASQIQVKREELITNWEQIRTLAAERHARLDDSYRLQRF 366
Query: 3057 YRDCEQADTWMSAREAFLAQEDPSGD--NVESLIKKHEDFDKAINTQEEKIKGLKLFAES 2884
D +W++ +A + ++ + D E+L+ +H++ I+ E+ K ++
Sbjct: 367 LADFRDLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQA 426
Query: 2883 LIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEK 2704
L+ +HY S V K + + L E +R + + LQ F RD ++++NWM+++
Sbjct: 427 LLAASHYASDEVREKLSILSEERTALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQ 486
Query: 2703 FQIAQEENYRDP-TNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAV 2527
E+ D +++ +K + FE L A ++I A+ + LI+N + V
Sbjct: 487 EAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMED--V 544
Query: 2526 SARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGE 2386
+ R AL + + L + + +L ++ + F +L+ W+ E
Sbjct: 545 ATRRDALLSRRNALHERAMHRRAQLADSFHLQQFFRDSDELKSWVNE 591
Score = 202 bits (514), Expect = 1e-49
Identities = 131/531 (24%), Positives = 242/531 (44%), Gaps = 8/531 (1%)
Frame = -1
Query: 5937 PESPEVQEKLEKLDHEKSSLLGLWEE-------RRILYEQCMDLQLFYRDTEQAETWMNK 5779
P +V E E + + +L + RR E Q F RD E+ E W+ +
Sbjct: 3 PSGVKVLETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQE 62
Query: 5778 QEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVA 5599
+ ++ + D + ++ ++KH+ FE + A I LDE +I H+A++ +
Sbjct: 63 KLQVASDENYKDPTN-LQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIR 121
Query: 5598 EXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSY-LDP 5422
+G L ++ K + R+C++++ WI +K + + D
Sbjct: 122 TRLMELHRQWELLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDL 181
Query: 5421 TNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELV 5242
++ +K F+ +L A+E R++++ ++I H + I + +VN W L
Sbjct: 182 EHVEVLQKKFEEFQTDLAAHEERVNEVSQFAAKLIQEQHPEEELIKTKQDEVNAAWQRLK 241
Query: 5241 DATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIE 5062
++ KL A Q+FNR++++ W+ E E +AS+D+G+DL SVQ L +K +E
Sbjct: 242 GLALQRQGKLFGAAEVQRFNRDVDETIGWIKEKEQLMASDDFGRDLASVQALLRKHEGLE 301
Query: 5061 SDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESH 4882
D A D+V + A + Q+ +A I K+E L + +R +R +L +S+
Sbjct: 302 RDLAALEDKVKALCAEADRLQQSHPLSASQIQVKREELITNWEQIRTLAAERHARLDDSY 361
Query: 4881 QGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVS 4702
+ + D D +W+ E + + + D+ G + L+ + Q EI H+ +S
Sbjct: 362 RLQRFLADFRDLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDAHEDSFKSAD 421
Query: 4701 SAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADA 4522
+ ++ H+ + E+R+KL+ L + L E RR + + + D + D
Sbjct: 422 ESGQALLAASHYASDEVREKLSILSEERTALLELWELRRQQYEQCMDLQLFYRDTEQVDN 481
Query: 4521 WMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQ 4369
WMS++E + + D G DS EALLKKH L A + I L + A++
Sbjct: 482 WMSKQEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATK 532
Score = 197 bits (502), Expect = 2e-48
Identities = 141/593 (23%), Positives = 293/593 (48%)
Frame = -1
Query: 2529 VSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGK 2350
+ R + + D++ + +T + +L+++ + + F ++LE W+ E + E+Y K
Sbjct: 15 IQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQVASDENY-K 73
Query: 2349 DLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDG 2170
D +++ L+KH EA++ A+ + +++E + ++ F + I R + +++
Sbjct: 74 DPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLMELHRQWEL 133
Query: 2169 VKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRR 1990
+ + ++ KL +A + Q+ R+ +D WI +K+ +V+S++ G+DL V+ L++K
Sbjct: 134 LLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQKKFEE 193
Query: 1989 IDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQR 1810
T+LA+HE +V+ V +L++ E E+ IK + +++ +W +++ L R +
Sbjct: 194 FQTDLAAHEERVNEVSQFAAKLIQ---EQHPEEELIKTKQDEVNAAWQRLKGLALQRQGK 250
Query: 1809 LDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQR 1630
L + Q F DV+E W+ EK+Q++ SD+FG ++A VQ LL+KH+ + DL + +
Sbjct: 251 LFGAAEVQRFNRDVDETIGWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLAALEDK 310
Query: 1629 VADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKC 1450
V L + D L + A I+ + ++L +I ++A R A+L D+ +F+
Sbjct: 311 VKALCAEADRLQQSHPLSASQIQVKREELITNWEQIRTLAAERHARLDDSYRLQRFLADF 370
Query: 1449 DVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVS 1270
+ SW+ E + + +++ D++ + LL + + ++A E + + E L++
Sbjct: 371 RDLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDAHE-DSFKSADESGQALLA 429
Query: 1269 SEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNS 1090
+ H S + ++ + + + LL E RR +L L F + ++
Sbjct: 430 ASHYASDEVREKLSILSEERTALLELWELRRQQYEQCM-------DLQL-FYRDTEQVDN 481
Query: 1089 WFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPN 910
W E L + +SL+ + AL H +F++SLS+ EE L + ++ + N
Sbjct: 482 WMSKQEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKL----IQNN 537
Query: 909 PYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLANAFH 751
Y A+ED + R+ L+R R +++ A+LA++FH
Sbjct: 538 HY------AMED-------VATRRDALLSR---RNALHERAMHRRAQLADSFH 574
Score = 197 bits (500), Expect = 4e-48
Identities = 146/577 (25%), Positives = 276/577 (47%), Gaps = 34/577 (5%)
Frame = -1
Query: 4971 IVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGR 4792
I +++ + RY+ ++ R++KL +S++ RD E+ WI+EK QVA N +
Sbjct: 15 IQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQVASDENY-K 73
Query: 4791 DLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRI 4612
D +Q ++K QA AE+ + I + N MI +GHF + IR +L +L W +
Sbjct: 74 DPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLMELHRQWEL 133
Query: 4611 LKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRA 4432
L K ++ L + + QYL + + W+++KE IV S + G+D + E L KK
Sbjct: 134 LLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQKKFEE 193
Query: 4431 LLSDLEAFKGTIEDLRKQASQCKYQEQPMGQL---GRDCVLALYD--------------- 4306
+DL A + + ++ + A++ ++ P +L +D V A +
Sbjct: 194 FQTDLAAHEERVNEVSQFAAKLIQEQHPEEELIKTKQDEVNAAWQRLKGLALQRQGKLFG 253
Query: 4305 --YQEKSPREVS-----MKKGDVLTLLNASNRDWWKVE--VNDRQGFVP--AAYVKRIEP 4159
++ R+V +K+ + L + RD V+ + +G AA +++
Sbjct: 254 AAEVQRFNRDVDETIGWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLAALEDKVKA 313
Query: 4158 GTAQQHAQQQ-----VNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDL 3994
A+ QQ + I K+ E+ ++++ L R +L+++ + + L + DL
Sbjct: 314 LCAEADRLQQSHPLSASQIQVKREELITNWEQIRTLAAERHARLDDSYRLQRFLADFRDL 373
Query: 3993 AEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQT 3814
W+ +A+ E+ D+ E L + + KG++ A+E + ++ AL +
Sbjct: 374 TSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQALLAASH- 432
Query: 3813 ETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDS 3634
+ +R+++ L+ AL Q ++Q F+RD ++ +W+ +++ L +
Sbjct: 433 YASDEVREKLSILSEERTALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLN 492
Query: 3633 EDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELN 3454
ED G L SV+AL +KHE E+ L+A +KI +LDE A +L Q++ A E + + L
Sbjct: 493 EDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMEDVATRRDALL 552
Query: 3453 EQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWI 3343
+ N L +A +R+ +L DS+ Q+F D +L W+
Sbjct: 553 SRRNALHERAMHRRAQLADSFHLQQFFRDSDELKSWV 589
Score = 183 bits (465), Expect = 5e-44
Identities = 134/589 (22%), Positives = 265/589 (44%), Gaps = 40/589 (6%)
Frame = -1
Query: 4662 APEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTD 4483
A +I+++ Q+ D + K + RR L+DS + + DA E + W+ EK + +
Sbjct: 12 AEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQVASDEN 71
Query: 4482 YGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQA----SQCKYQEQPMG----QLGRD 4327
Y KD + + L+KH+A ++++A G I L + S+ + + + +L R
Sbjct: 72 Y-KDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLMELHRQ 130
Query: 4326 CVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVP------------- 4186
L L +EK + + +K DW +ND++ V
Sbjct: 131 WELLLEKMREKGIKLLQAQKLVQYLRECEDVMDW----INDKEAIVTSEELGQDLEHVEV 186
Query: 4185 ------------AAYVKRIEPGTA-------QQHAQQQVNSIGGKQSEIEDKYQRLMMLG 4063
AA+ +R+ + +QH ++++ I KQ E+ +QRL L
Sbjct: 187 LQKKFEEFQTDLAAHEERVNEVSQFAAKLIQEQHPEEEL--IKTKQDEVNAAWQRLKGLA 244
Query: 4062 ETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDL 3883
R+ KL A + + R+ ++ WIK +E + A + G DL V+ L +K + + DL
Sbjct: 245 LQRQGKLFGAAEVQRFNRDVDETIGWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDL 304
Query: 3882 KANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEV 3703
A E +++ + A L +A +I+ + E+L W + +L ++ +
Sbjct: 305 AALEDKVKALCAEADRLQQ-SHPLSASQIQVKREELITNWEQIRTLAAERHARLDDSYRL 363
Query: 3702 QRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEK 3523
QRF D + W+ E +++++ D+ +AL +H+ + ++ A D KS DE
Sbjct: 364 QRFLADFRDLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDAHEDSFKSADES 423
Query: 3522 ANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWI 3343
L + A++++ + L+E+ L R+++ D Q F D + W+
Sbjct: 424 GQALLAASHYASDEVREKLSILSEERTALLELWELRRQQYEQCMDLQLFYRDTEQVDNWM 483
Query: 3342 ASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGD 3163
+ + +++L + + EALL++H+++ + ++ A D+F +L+ ++HYA D
Sbjct: 484 SKQEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMED 543
Query: 3162 IENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAR 3016
+ R + R L + + RR L LQ F+RD ++ +W++ +
Sbjct: 544 VATRRDALLSRRNALHERAMHRRAQLADSFHLQQFFRDSDELKSWVNEK 592
Score = 44.3 bits (103), Expect = 0.045
Identities = 19/61 (31%), Positives = 36/61 (58%)
Frame = -1
Query: 7197 DDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENF 7018
+D+ RR +L + + + +R +L ++ Q F RD+DEL W+ EK++TA +E +
Sbjct: 542 EDVATRRDALLSRRNALHERAMHRRAQLADSFHLQQFFRDSDELKSWVNEKMKTATDEAY 601
Query: 7017 R 7015
+
Sbjct: 602 K 602
>gi|7506776|pir||T23630 hypothetical protein R31.1 - Caenorhabditis
elegans
Length = 4101
Score = 652 bits (1681), Expect = 0.0
Identities = 548/2272 (24%), Positives = 1003/2272 (44%), Gaps = 74/2272 (3%)
Frame = -1
Query: 6801 LQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELG-NHQY 6625
L +KLL F R+CDE W +E E + E EHV +RKFD ++ N
Sbjct: 953 LSDNIKLLRFYRECDEFERWAKEIEVSLADEPSP---EHVAAFRRKFDKLEADMKTNGGT 1009
Query: 6624 RINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRD 6445
++ IN A+ L+ EGH + +I ++ +N W L L R L +V F+
Sbjct: 1010 QLKHINDIANDLISEGHGQSRKIEVRQHKINAMWDNLERLRKQRGVRLEATERVADFDTT 1069
Query: 6444 ADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAE 6265
+ W+ K + R+ N+V++LQ ERDL LE K+ LEK A + +
Sbjct: 1070 CESAREWMLSK-----FEQLDRNPNDVKSLQN----LERDLKPLEDKIAALEKLAAAVKK 1120
Query: 6264 THPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAV 6085
HP+ A AI +K + +A L +AQ + E++ F + RD+I WI + V
Sbjct: 1121 DHPEEAAAIERKIAELRALHADLLRRAQEKMLLAEQTQGKEMFESALRDMIGWIEKTRKV 1180
Query: 6084 IGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLE 5905
+ D DVA AE LL+ H E +I + G++L+E P +V+E+L+
Sbjct: 1181 MMEDVHPVDVAEAEELLKKHYELGEQIKDKKYEVEYCQELGRRLLERN-PRMSKVEEQLQ 1239
Query: 5904 KLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVE 5725
L E +SL L+ R + +Q +DLQLF R++E+ + EAFL +LGDS++SVE
Sbjct: 1240 NLVSEMASLRDLYRRRDTILKQQLDLQLFNRESERIDAATKGHEAFLEFDNLGDSVESVE 1299
Query: 5724 HLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXX 5545
+L+K+H D E L AQE ++ A A +I+ QH + + +
Sbjct: 1300 NLLKRHRDLEAKLDAQEARLEAFSRTADDMIKAQHADSAYIEQRRRDVLARREAVRRAAA 1359
Query: 5544 XRGNALKESYKRQTFDRDCDEMVSWITEK--LSTARDDSYLDPTNIRGKLQKHINFEQEL 5371
R L+ S + Q R+ DE+V W+ EK L + DDS L P+ I +L KH FE E+
Sbjct: 1360 QRKKQLEASLEYQEMRREADEVVGWMYEKAKLVMSGDDSALAPSAIPHRLLKHEAFEAEI 1419
Query: 5370 KANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQ 5191
ANE R+ I S G+ ++ H+ + ++ +RQVN W +L KG +LR+A +++
Sbjct: 1420 IANEPRIQQINSEGDGLVSKKHYESPNVEKIVRQVNAQWGDLKKQVWNKGLRLRQAADQK 1479
Query: 5190 QFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLA 5011
+R +ED A L E++ + S+D G DL SV++L +K ++E + + +++ I+
Sbjct: 1480 GLDRILEDAHAKLDEMQTALNSKDQGLDLRSVKDLLQKHAVLEQEMGLYGNKLSDIENRG 1539
Query: 5010 QQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIR 4831
++ + H++A I L QRY A++ P ++RK L ES +QL D++ EL WI
Sbjct: 1540 KKMAVDGHYDADRIHSTVGQLLQRYAAMKGPAQRRKGDLDESRLWHQLVFDVDCELQWIA 1599
Query: 4830 EKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEI 4651
EK+ +A S + GR L N++KKQ+ L AE+ H QI+ V A ++I++ H + +I
Sbjct: 1600 EKKPIASSQDCGRTLTEALNMVKKQEQLEAEVNQHGGQIDKVLLQAGELIKRHHSASSQI 1659
Query: 4650 RDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKD 4471
+ K ++L W LK RR +D ++ QYL DA E ++WM+EK + S DYG D
Sbjct: 1660 KAKSSELETAWSELKKLLRLRRAVVDWGVKEQQYLFDAAEVESWMNEKRNALASEDYGND 1719
Query: 4470 EDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQP------------------M 4345
ED+A LL KHRAL D+ ++ +E L + + +P +
Sbjct: 1720 EDAARKLLSKHRALCEDMTTYRQWLEKLEVKCVELVESNRPHVERFQKRQDELVREFDAL 1779
Query: 4344 GQLGRD------CVLALYDY-QEKSPREVSMKKGDVLTLLNASNRDWWKV-EVNDRQGFV 4189
+L D + LY+Y +E + S+++ + + D+ + E+ +
Sbjct: 1780 SKLAEDRRNALEDAVCLYEYMRESADLGQSIEENLRVAMSEEFAEDYEHLKELQSKFDEF 1839
Query: 4188 PAAYVKRIEPGTAQQHAQQQV--------NSIGGKQSEIEDKYQRLMMLGETRKRKLEEA 4033
E T+ + A + + KQ + + L E R KL A
Sbjct: 1840 KQKVKNGSERFTSCETAANAILRRNPPFARDVVKKQEALRTAWNTLCEYIEARDSKLAVA 1899
Query: 4032 CKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEM 3853
+ ++ R+ ++ +W+ + A +++G D++ V L + + ++ ++ RL ++
Sbjct: 1900 EELHRFHRDVDEFEQWMADKMA-NMPRDLGRDVKHVHSLWQHHEALDKEIHNSQPRLAKL 1958
Query: 3852 NQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDET 3673
+ A L A +I + + L W L L +A ++ F+ V +
Sbjct: 1959 VEEAERLKKTYPGGNAEQIGGRQQTLEQEWEELKNATDDRKDMLRAAFDLHTFNGKVRDL 2018
Query: 3672 RDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPE 3493
W + S+ DL+ + LQ +H + ++ A + L ++ +
Sbjct: 2019 LAWTDLTISDIQSDLHINDLQQAEWLQTEHSRLSHEMDAREPEFARLVNDGEKMITAQHY 2078
Query: 3492 AAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQ 3313
A+E+I + L RL S+ R L + + F + + ++ I S + S
Sbjct: 2079 ASEEIKNKTHLLKSALERLRSEWALRNGFLSQAVQWHAFQREAKQIIASIGSKRTTLRSL 2138
Query: 3312 ELANDVTGAEALLERHQEYR---TEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQG 3142
+ V E+ +R + + +D R AT D N+L+ + H + +I
Sbjct: 2139 AVGGSVADVESQTKRLDTFEKALSTLDERTAT---LDHTANELMKARHMESKNISMWQSN 2195
Query: 3141 VNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMS------AREAFLAQEDPSGD 2980
V+E K L AR +L L F D Q + W+ + L+ E S D
Sbjct: 2196 VHEELKLLRQDIEARHAMLKDAFALASFDSDVAQIEAWIDEKTNGVRKAQDLSSESISID 2255
Query: 2979 NVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKE 2800
++ H+ + + + + + L + +KN H +P + + D++ +WN L
Sbjct: 2256 EKMKRLQTHQALEAEVTANKPVVDQI-LQRGNQLKNLH-RNPKIANRCDELSYKWNQLSG 2313
Query: 2799 ALIQKRFKLGESQTLQQFSRDADEIENWMTEK-FQIAQEENYRDPTNIQQKHQKQQAFEA 2623
A + L E++ L +F + + + W+ EK ++ + +D + + ++ +
Sbjct: 2314 ACADQSLALEEARDLLRFKQLVENVLAWINEKEVLVSTADMGKDMEHCRLLLERLDGTRS 2373
Query: 2622 ELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEA 2443
+ + + I + G L++ + + V + LN++W LL+ L A
Sbjct: 2374 DSIVDEQTLDEINRLGEKLVKQGRSSRDQ--VQKEQQHLNEKWRLLLGQLAHYRTELLAA 2431
Query: 2442 NKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEM 2263
+ +F V+D + + E ++S+DYGKD ASVE L++K S LE D+ A ++
Sbjct: 2432 MEVHTFNRDVEDTDERIHEKVAAMKSDDYGKDFASVELLVRKQSALERDMSAIHQKLIAH 2491
Query: 2262 NEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEE 2083
++ A +LE + + + K + + ++ + K A R +KL+++ ++++ D+ E
Sbjct: 2492 DKDAQKILEKRPPLRETVLDSLKKLEESWEQLSKAAELRNEKLNRSFKLYKYLDDVKKVE 2551
Query: 2082 SWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEA 1903
W + + ++S +D G + + +H E+ ++ L+ +G+ L + E
Sbjct: 2552 QWANQVRNKMTSHQTPKDSNGARKILEQHHERKAEIDGRSEELRLLHEEGQALNQEQPEH 2611
Query: 1902 GVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILG 1723
+ KR+++ E Q+R + L + + + + + E W+++K+ +
Sbjct: 2612 KAEVQRAHKRVQNSEH---QLRQTWESEKGTLQKLLEWMLWCDEAVQCEQWLSDKETQVA 2668
Query: 1722 SDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQL 1543
G+ V+ L+K H F+ + +++ L D L+ GN++ I R +++
Sbjct: 2669 RGELGDTTDAVEMLIKGHSAFEETVRKQSEKIDALTKNADALVSGGNNYRADIVTRSEEV 2728
Query: 1542 RARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQIL 1363
AR + E R L D+ Y +F+ +C + WI K Q E F D ++++
Sbjct: 2729 TARHALLLKSMEKRGHMLEDSKKYHEFIRQCGELIIWITAKLQLAYDESF-LDHTNLRSK 2787
Query: 1362 LTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEA 1183
L K AFD+ L E + + + +QLV+ H S ++ + + W L S
Sbjct: 2788 LQKHMAFDSELVENE-KRLSTVERQGEQLVTDNHFMSEQVKAQLVELRSGWDELRTKSAL 2846
Query: 1182 RRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHG 1003
+ EL+ + +K W + E +L+ D HG
Sbjct: 2847 KTQRLREAF-------ELH-SLQRKVEDIEKWLDKVEGELSS--------------DDHG 2884
Query: 1002 EFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRI--------- 850
R + S E ++L L I DA+ + + + +
Sbjct: 2885 ---RDILSTELLIKKLDTLQTEIAG-----------RSDAVVEMMKKARELRVQGSAAAD 2930
Query: 849 --IKEREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEMM------------EA 712
+K+ EQ AR + +E ++RRE A AF W+ +++ E+
Sbjct: 2931 DCLKQAEQVEAR-YSGLDEPVQIRRENLVDAQAFFQWVKAAEEDLEWLSDRMMLASSGES 2989
Query: 711 GGTLEEQLDAVERKA---KEIKANKGQLRQIEEKGAMLERNLILDNRYTEHSTVGIAQAW 541
G +L+ L ++ A KE+ + + E++G + R + + + ++ A
Sbjct: 2990 GDSLQSALSLQKKHATLEKELDTRQSAMNDTEQRGKDMIRQRHFASTHIQKILDRLSSAM 3049
Query: 540 DQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMMFKHFDKEKTGRLDHQQFKSCLRA 361
L + + L++ I A EA + ++ GR D +S LR
Sbjct: 3050 LTLKESCGLRRDLLQEAIDAHEYYTEETEAEQWLREQMPLAMSQEMGR-DQAGAESHLRR 3108
Query: 360 LGYDLPMVDEGQPEPE-FQRILDIVDPNRDGYVTLQEYMAFMISKETENIQS 208
L ++D+ E E F+ +D + DG + + + A I+ + +++
Sbjct: 3109 ----LTVLDK---EVELFKNEIDRLKKRADGLLAREHHDAMSIAAKQRKLEA 3153
Score = 558 bits (1439), Expect = e-157
Identities = 362/1353 (26%), Positives = 660/1353 (48%), Gaps = 46/1353 (3%)
Frame = -1
Query: 7152 IFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEK---LQTAQEENFRDPS--NLQAKI 6988
+ + + + L++A F D ++ WI EK ++ AQ+ + S ++
Sbjct: 2202 LLRQDIEARHAMLKDAFALASFDSDVAQIEAWIDEKTNGVRKAQDLSSESISIDEKMKRL 2261
Query: 6987 QKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKG 6808
Q H+A EAEV A+ + + + GN + N + I R +EL W +
Sbjct: 2262 QTHQALEAEVTANKPVVDQILQRGNQL--KNLHRNPKIANRCDELSYKWNQLSGACADQS 2319
Query: 6807 IKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQ 6628
+ L++A LL F + + +L WI EKE V+ DMG D+EH +L + D + +
Sbjct: 2320 LALEEARDLLRFKQLVENVLAWINEKEVLVSTADMGKDMEHCRLLLERLDGTRSDSIVDE 2379
Query: 6627 YRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNR 6448
++EIN+ +KLV++G S DQ+ K++ +N+ W L A + L A +V FNR
Sbjct: 2380 QTLDEINRLGEKLVKQGRSSRDQVQKEQQHLNEKWRLLLGQLAHYRTELLAAMEVHTFNR 2439
Query: 6447 DADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLA 6268
D ++T I EK A+ SDDYG+D +V+ L RK ERD++A+ K++ +K+A K+
Sbjct: 2440 DVEDTDERIHEKVAAMKSDDYGKDFASVELLVRKQSALERDMSAIHQKLIAHDKDAQKIL 2499
Query: 6267 ETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKA 6088
E P E + + +W L + A+ R + L RSF+L+++L D + + W ++
Sbjct: 2500 EKRPPLRETVLDSLKKLEESWEQLSKAAELRNEKLNRSFKLYKYLDDVKKVEQWANQVRN 2559
Query: 6087 VIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKL 5908
+ + + KD GA +LE H E K EID R++ GQ L + EVQ
Sbjct: 2560 KMTSHQTPKDSNGARKILEQHHERKAEIDGRSEELRLLHEEGQALNQEQPEHKAEVQRAH 2619
Query: 5907 EKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSV 5728
+++ + + L WE + ++ ++ L+ + Q E W++ +E +A +LGD+ D+V
Sbjct: 2620 KRVQNSEHQLRQTWESEKGTLQKLLEWMLWCDEAVQCEQWLSDKETQVARGELGDTTDAV 2679
Query: 5727 EHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXX 5548
E LIK H FE+++ Q EKI+AL + A L+ G + D+
Sbjct: 2680 EMLIKGHSAFEETVRKQSEKIDALTKNADALVSGGNNYRADIVTRSEEVTARHALLLKSM 2739
Query: 5547 XXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQELK 5368
RG+ L++S K F R C E++ WIT KL A D+S+LD TN+R KLQKH+ F+ EL
Sbjct: 2740 EKRGHMLEDSKKYHEFIRQCGELIIWITAKLQLAYDESFLDHTNLRSKLQKHMAFDSELV 2799
Query: 5367 ANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQ 5188
NE RL + GEQ++ HF ++ + +L ++ + W+EL + K +LREA
Sbjct: 2800 ENEKRLSTVERQGEQLVTDNHFMSEQVKAQLVELRSGWDELRTKSALKTQRLREAFELHS 2859
Query: 5187 FNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQ 5008
R +ED+E WL ++EG+++S+D+G+D++S + L KK+ ++++ +D V + + A+
Sbjct: 2860 LQRKVEDIEKWLDKVEGELSSDDHGRDILSTELLIKKLDTLQTEIAGRSDAVVEMMKKAR 2919
Query: 5007 QFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIRE 4828
+ + + A +++ E ++ RY+ L +P++ R+ L ++ Q + E++L W+ +
Sbjct: 2920 ELRVQGSAAADDCLKQAEQVEARYSGLDEPVQIRRENLVDAQAFFQWVKAAEEDLEWLSD 2979
Query: 4827 KEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIR 4648
+ +A S G L +L KK L E+ S + DMI+Q HF + I+
Sbjct: 2980 RMMLASSGESGDSLQSALSLQKKHATLEKELDTRQSAMNDTEQRGKDMIRQRHFASTHIQ 3039
Query: 4647 DKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDE 4468
L +L LK RR L +++ AH+Y ++ EA+ W+ E+ P+ S + G+D+
Sbjct: 3040 KILDRLSSAMLTLKESCGLRRDLLQEAIDAHEYYTEETEAEQWLREQMPLAMSQEMGRDQ 3099
Query: 4467 DSAEALLKKHRALLSDLEAFKGTIEDLRKQ---------------ASQCKYQEQPMGQLG 4333
AE+ L++ L ++E FK I+ L+K+ A++ + E G L
Sbjct: 3100 AGAESHLRRLTVLDKEVELFKNEIDRLKKRADGLLAREHHDAMSIAAKQRKLEALFGDLC 3159
Query: 4332 RDCVLALYDYQEKSPREVSMKKGDVLT------LLNASNRDWWKVEVNDRQGFVP--AAY 4177
R+C + S +++ D L+ +AS D+ + ++ D Q + +
Sbjct: 3160 RECARRRTQIVDASKYHKFVRQADDLSDWLREKERSASAEDYGQ-DLEDCQQIIEQFEST 3218
Query: 4176 VKRI----EPGTAQQHAQQQV--------NSIGGKQSEIEDKYQRLMMLGETRKRKLEEA 4033
V+ + E A Q AQ+ + SI K ++++ + + + RK+ L A
Sbjct: 3219 VRELAAAGERVAAVQRAQEDLLRSGHPYGASITAKGADVQRLWTHVNEVANERKQALNGA 3278
Query: 4032 CKGYQLLREANDLAEWIKSREA--VAAQQE--IGTDLEQVEVLQKKFDDFKGDLKANEVR 3865
+ ++ +EA+ + W++ +EA VA +QE DL V+ ++ D+F +KA E +
Sbjct: 3279 RQVHRFDQEADQILNWLQDKEATGVAMEQEDLSRADLASVKAQLQRHDEFMHGMKAVEKQ 3338
Query: 3864 LQEMNQIATAL-TSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHR 3688
+ E+ A L S T + +R+ D+ + + + +L +Q + +
Sbjct: 3339 VAELCHEAERLWNSFPDTRHHLEVRRL--DMEEQLKDILEAAKKHLEKLRHMQSLQSYFQ 3396
Query: 3687 DVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLR 3508
+ E W++ + SE RD+ S ++L R+H+ ++ + + R+
Sbjct: 3397 EYREMMQWMKNMQSTMTSEQLPRDVASCESLVRRHDEYNLEMQGRKPFVDDFARQGRRMI 3456
Query: 3507 QSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQ 3328
QS +++I + L + W L +R E ++ D Q++ + L W+
Sbjct: 3457 QSSHVLSQEIQEKVDILEKSWAMLCEIWKDRAELYEENMDVQKWKQNAEQLDSWLEERAG 3516
Query: 3327 LVSSQ-ELANDVTGAEALLERHQEYRTEIDSRA 3232
L+ + + V AE L ++ +++++
Sbjct: 3517 LLGDDWRMVDSVEMAETHLRDFDDFLVTLEAQS 3549
Score = 558 bits (1438), Expect = e-157
Identities = 420/1600 (26%), Positives = 731/1600 (45%), Gaps = 35/1600 (2%)
Frame = -1
Query: 5478 VSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFA 5299
V + E++ R S ++ T L+K ++ A E+R + + ++ +
Sbjct: 461 VQVVLEEMEHGRSASQVEKT-----LKKQQAISTDILAREDRFKMLTAMCNELCTEKYHE 515
Query: 5298 ADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASED 5119
+D + R++ + W +L+ ++ L + R+I+ + L LE V + D
Sbjct: 516 SDKVRGMEREIIDRWTQLLTLLEQRKRALMSLNDLMSLLRDIDTLSNELYSLEPAVRNRD 575
Query: 5118 YGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQR 4939
GK L+ V++L K L+++ NAH + + Q A + + V+ RK + + +
Sbjct: 576 VGKHLIGVEDLLGKHDLLDAQINAHGSLLSKLSQSANNYIRHKEEQFDVLQRKLDEVTAQ 635
Query: 4938 YNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKK 4759
YN L + R+ L + Q +D E+E+AW+ EKE++ + D+ V
Sbjct: 636 YNTLVELCRSRRLGLERARSLFQFVQDHEEEMAWLAEKEKLCTTALNSGDISAVPQTTLL 695
Query: 4758 QQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTD 4579
+ + E+ H ++ + + + ++Q G +I+ +L Q+ W L+ +
Sbjct: 696 YKNVEMEMQTHWARSKGMIAGGERLVQNGQ-SKEDIQRRLTQMNHRWERLRVAVDALGNW 754
Query: 4578 LDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGT 4399
L ++ A QY DANEA++W+ EK P+V S D G+DE +AE+LL++H L ++ A+K
Sbjct: 755 LSEARHAQQYFQDANEAESWIREKMPLVKSDDLGRDEGAAESLLQRHARLEEEIRAYKSD 814
Query: 4398 IEDLRKQASQ----------CKYQEQPMGQLGRDCVLALYDYQEKSPREVSMKKGDVLTL 4249
I L + SQ Q ++ V Y+Y+ R + KG+VL L
Sbjct: 815 ISRLEEMQSQLANSAFHTATTSQSVQETEEVNVPQVEMSYNYEGNGMR---VSKGEVLAL 871
Query: 4248 LNASNRDWWKVEVND-RQGFVPAAYVKRIEPG---TAQQHAQQQVNSIGG---------- 4111
L S +WW+ D +G+VPA Y K I PG T Q Q+ ++ G
Sbjct: 872 LEKSTPEWWRALKRDGTEGYVPANYCK-IVPGETVTVTQTTQKTTTTLEGNETKSSVVAD 930
Query: 4110 KQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLE 3931
+Q +I + Y+ L L + R+R L + K + RE ++ W K E A + E
Sbjct: 931 RQHKISNDYRELKRLADVRRRLLSDNIKLLRFYRECDEFERWAKEIEVSLADE---PSPE 987
Query: 3930 QVEVLQKKFDDFKGDLKAN-EVRLQEMNQIATALTSVGQTET-AVRIRQQIEDLNARWRA 3757
V ++KFD + D+K N +L+ +N IA L S G ++ + +RQ +NA W
Sbjct: 988 HVAAFRRKFDKLEADMKTNGGTQLKHINDIANDLISEGHGQSRKIEVRQ--HKINAMWDN 1045
Query: 3756 LXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEG 3577
L +L + V F + R+W+ K + LD R+ V++LQ
Sbjct: 1046 LERLRKQRGVRLEATERVADFDTTCESAREWMLSKFEQLD-----RNPNDVKSLQ----N 1096
Query: 3576 VERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLD 3397
+ERDL L DKI +L++ A +++ HPE A I EL L +A +
Sbjct: 1097 LERDLKPLEDKIAALEKLAAAVKKDHPEEAAAIERKIAELRALHADLLRRAQEKMLLAEQ 1156
Query: 3396 SYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQA 3217
+ + F S RD++ WI +++ DV AE LL++H E +I + +
Sbjct: 1157 TQGKEMFESALRDMIGWIEKTRKVMMEDVHPVDVAEAEELLKKHYELGEQIKDKKYEVEY 1216
Query: 3216 FDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQA 3037
+ G +LL + +E +LQ + L D + R IL Q L+LQLF R+ E+
Sbjct: 1217 CQELGRRLL-ERNPRMSKVEEQLQNLVSEMASLRDLYRRRDTILKQQLDLQLFNRESERI 1275
Query: 3036 DTWMSAREAFLAQEDPSGDNVES---LIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNH 2866
D EAFL + D GD+VES L+K+H D + ++ QE +++ A+ +IK H
Sbjct: 1276 DAATKGHEAFL-EFDNLGDSVESVENLLKRHRDLEAKLDAQEARLEAFSRTADDMIKAQH 1334
Query: 2865 YDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQ- 2689
DS + ++R +L R ++ A Q++ +L S Q+ R+ADE+ WM EK ++
Sbjct: 1335 ADSAYIEQRRRDVLARREAVRRAAAQRKKQLEASLEYQEMRREADEVVGWMYEKAKLVMS 1394
Query: 2688 -EENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLK 2512
+++ P+ I + K +AFEAE+ AN RI I G+ L+ +K V ++
Sbjct: 1395 GDDSALAPSAIPHRLLKHEAFEAEIIANEPRIQQINSEGDGLV--SKKHYESPNVEKIVR 1452
Query: 2511 ALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVE 2332
+N QW L K K RL++A QK ++D L E++ L S+D G DL SV+
Sbjct: 1453 QVNAQWGDLKKQVWNKGLRLRQAADQKGLDRILEDAHAKLDEMQTALNSKDQGLDLRSVK 1512
Query: 2331 NLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMAT 2152
+LL+KH++LE ++ + +++ ++ + + + + +I + RY +K A
Sbjct: 1513 DLLQKHAVLEQEMGLYGNKLSDIENRGKKMAVDGHYDADRIHSTVGQLLQRYAAMKGPAQ 1572
Query: 2151 DRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELA 1972
R+ L ++ HQ D+D E WI EKK + SS D GR L N+ +K +++ E+
Sbjct: 1573 RRKGDLDESRLWHQLVFDVDCELQWIAEKKPIASSQDCGRTLTEALNMVKKQEQLEAEVN 1632
Query: 1971 SHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEA 1792
H Q+ V L+ EL++ A QIK + +LE +W +++ L R +D
Sbjct: 1633 QHGGQIDKVLLQAGELIKRHHSA---SSQIKAKSSELETAWSELKKLLRLRRAVVDWGVK 1689
Query: 1791 FQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLIN 1612
Q +L D E E+WMNEK+ L S+++G + + LL KH D+ ++Q + L
Sbjct: 1690 EQQYLFDAAEVESWMNEKRNALASEDYGNDEDAARKLLSKHRALCEDMTTYRQWLEKLEV 1749
Query: 1611 KGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESW 1432
K L+ + H ++R D+L + +AE R L D ++M + +
Sbjct: 1750 KCVELVESNRPHVERFQKRQDELVREFDALSKLAEDRRNALEDAVCLYEYMRESADLGQS 1809
Query: 1431 IAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQS 1252
I E + SE+F D ++ L +K + F + G +R T + + +
Sbjct: 1810 IEENLRVAMSEEFAEDYEHLKELQSKFDEFKQKVK----NGSERFTSCETAANAILRRNP 1865
Query: 1251 P---AIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFE 1081
P + K+ + W L + EAR EEL+ F + F W
Sbjct: 1866 PFARDVVKKQEALRTAWNTLCEYIEAR-------DSKLAVAEELH-RFHRDVDEFEQWMA 1917
Query: 1080 NAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQL-QDLDRRIKSFNVGPNPY 904
+ ++ + ++ + +L H + + +++ +L ++ +R K++ G
Sbjct: 1918 DKMANMPRDLG-RDVKHVHSLWQHHEALDKEIHNSQPRLAKLVEEAERLKKTYPGGNAEQ 1976
Query: 903 TWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLR 784
LE W L+ +R+ L N K+R
Sbjct: 1977 IGGRQQTLEQEWEELKNATDDRKDMLRAAFDLHTFNGKVR 2016
Score = 492 bits (1267), Expect = e-137
Identities = 453/2332 (19%), Positives = 981/2332 (41%), Gaps = 69/2332 (2%)
Frame = -1
Query: 7191 IHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEK--LQTAQEENF 7018
I QRR++VL + + ++ +LE + ++Q +R+ADE+ W+ EK L + +++
Sbjct: 1340 IEQRRRDVLARREAVRRAAAQRKKQLEASLEYQEMRREADEVVGWMYEKAKLVMSGDDSA 1399
Query: 7017 RDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWX 6838
PS + ++ KHEAFEAE+ A+ I ++ G+ ++ H+ S +++K + +++A W
Sbjct: 1400 LAPSAIPHRLLKHEAFEAEIIANEPRIQQINSEGDGLVSKKHYESPNVEKIVRQVNAQWG 1459
Query: 6837 XXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFD 6658
KG++L+QA R ++ + E +T + ++D G+DL V+ L +K
Sbjct: 1460 DLKKQVWNKGLRLRQAADQKGLDRILEDAHAKLDEMQTALNSKDQGLDLRSVKDLLQKHA 1519
Query: 6657 DFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLF 6478
+E+G + ++++I K+ +GH + D+I+ + + + A RK L
Sbjct: 1520 VLEQEMGLYGNKLSDIENRGKKMAVDGHYDADRIHSTVGQLLQRYAAMKGPAQRRKGDLD 1579
Query: 6477 GAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKML 6298
+ + D D L WI EK SS D GR L + +K E E ++ G++
Sbjct: 1580 ESRLWHQLVFDVDCELQWIAEKKPIASSQDCGRTLTEALNMVKKQEQLEAEVNQHGGQID 1639
Query: 6297 QLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRD 6118
++ +A +L + H + I K+ + + AW+ LK+ + R+ ++ + ++L D +
Sbjct: 1640 KVLLQAGELIKRHHSASSQIKAKSSELETAWSELKKLLRLRRAVVDWGVKEQQYLFDAAE 1699
Query: 6117 LISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGI 5938
+ SW+ + + + +++ D A LL H+ ++ + +LVE
Sbjct: 1700 VESWMNEKRNALASEDYGNDEDAARKLLSKHRALCEDMTTYRQWLEKLEVKCVELVESNR 1759
Query: 5937 PESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLAN 5758
P Q++ ++L E +L L E+RR E + L + R++ + + +
Sbjct: 1760 PHVERFQKRQDELVREFDALSKLAEDRRNALEDAVCLYEYMRESADLGQSIEENLRVAMS 1819
Query: 5757 TDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXX 5578
+ + + ++ L K ++F++ + E+ + + A +++ A DV +
Sbjct: 1820 EEFAEDYEHLKELQSKFDEFKQKVKNGSERFTSCETAANAILRRNPPFARDVVKKQEALR 1879
Query: 5577 XXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGKLQ 5398
R + L + + F RD DE W+ +K++ D D ++ Q
Sbjct: 1880 TAWNTLCEYIEARDSKLAVAEELHRFHRDVDEFEQWMADKMANMPRDLGRDVKHVHSLWQ 1939
Query: 5397 KHINFEQELKANENRLDDIRSTGEQI---IDSGHFAADHIGDRLRQVNNLWNELVDATNK 5227
H ++E+ ++ RL + E++ G+ A+ IG R + + W EL +AT+
Sbjct: 1940 HHEALDKEIHNSQPRLAKLVEEAERLKKTYPGGN--AEQIGGRQQTLEQEWEELKNATDD 1997
Query: 5226 KGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNA 5047
+ LR A + FN + D+ AW + S+ + DL + LQ + + + +A
Sbjct: 1998 RKDMLRAAFDLHTFNGKVRDLLAWTDLTISDIQSDLHINDLQQAEWLQTEHSRLSHEMDA 2057
Query: 5046 HNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQL 4867
+ ++ +H+ + I K L+ LR R L ++ Q +
Sbjct: 2058 REPEFARLVNDGEKMITAQHYASEEIKNKTHLLKSALERLRSEWALRNGFLSQAVQWHAF 2117
Query: 4866 FRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAAND 4687
R+ + +A I K S G + V++ K+ ++ D + ++ AN+
Sbjct: 2118 QREAKQIIASIGSKRTTLRSLAVGGSVADVESQTKRLDTFEKALSTLDERTATLDHTANE 2177
Query: 4686 MIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEK 4507
+++ H + I + + + ++L+ E R L D+ + SD + +AW+ EK
Sbjct: 2178 LMKARHMESKNISMWQSNVHEELKLLRQDIEARHAMLKDAFALASFDSDVAQIEAWIDEK 2237
Query: 4506 -EPIVGSTDYGKDEDSAEALLKK---HRALLSDLEAFKGTIEDLRKQASQCKYQEQPMGQ 4339
+ + D + S + +K+ H+AL +++ A K ++ + ++ +Q K + +
Sbjct: 2238 TNGVRKAQDLSSESISIDEKMKRLQTHQALEAEVTANKPVVDQILQRGNQLKNLHR-NPK 2296
Query: 4338 LGRDCVLALYDYQEKSP--REVSMKKGDVLTLLN----ASNRDWWKVEVNDRQGFVPAA- 4180
+ C Y + + S + S+ + LL N W +N+++ V A
Sbjct: 2297 IANRCDELSYKWNQLSGACADQSLALEEARDLLRFKQLVENVLAW---INEKEVLVSTAD 2353
Query: 4179 ----------YVKRIE----PGTAQQHAQQQVNSIGGK--------QSEIEDKYQRL--- 4075
++R++ + ++N +G K + +++ + Q L
Sbjct: 2354 MGKDMEHCRLLLERLDGTRSDSIVDEQTLDEINRLGEKLVKQGRSSRDQVQKEQQHLNEK 2413
Query: 4074 --MMLGETR--KRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKK 3907
++LG+ + +L A + + R+ D E I + A + G D VE+L +K
Sbjct: 2414 WRLLLGQLAHYRTELLAAMEVHTFNRDVEDTDERIHEKVAAMKSDDYGKDFASVELLVRK 2473
Query: 3906 FDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXX 3727
+ D+ A +L ++ A + + + ++ L W L
Sbjct: 2474 QSALERDMSAIHQKLIAHDKDAQKILE-KRPPLRETVLDSLKKLEESWEQLSKAAELRNE 2532
Query: 3726 QLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGD 3547
+L + ++ ++ DV + W + + + S +D + + +H + ++ +
Sbjct: 2533 KLNRSFKLYKYLDDVKKVEQWANQVRNKMTSHQTPKDSNGARKILEQHHERKAEIDGRSE 2592
Query: 3546 KIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSD 3367
+++ L E+ L Q PE ++ + + ++L + K L ++ + +
Sbjct: 2593 ELRLLHEEGQALNQEQPEHKAEVQRAHKRVQNSEHQLRQTWESEKGTLQKLLEWMLWCDE 2652
Query: 3366 YRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLN 3187
QW++ V+ EL + E L++ H + + ++ A + + L++
Sbjct: 2653 AVQCEQWLSDKETQVARGELGDTTDAVEMLIKGHSAFEETVRKQSEKIDALTKNADALVS 2712
Query: 3186 SHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAF 3007
+ DI R + V L + R ++L+ + F R C + W++A+
Sbjct: 2713 GGNNYRADIVTRSEEVTARHALLLKSMEKRGHMLEDSKKYHEFIRQCGELIIWITAK-LQ 2771
Query: 3006 LAQEDPSGD--NVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRD 2833
LA ++ D N+ S ++KH FD + E+++ ++ E L+ +NH+ S V +
Sbjct: 2772 LAYDESFLDHTNLRSKLQKHMAFDSELVENEKRLSTVERQGEQLVTDNHFMSEQVKAQLV 2831
Query: 2832 QILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTE-KFQIAQEENYRDPTNIQ 2656
++ W+ L+ K +L E+ L R ++IE W+ + + +++ +++ RD + +
Sbjct: 2832 ELRSGWDELRTKSALKTQRLREAFELHSLQRKVEDIEKWLDKVEGELSSDDHGRDILSTE 2891
Query: 2655 QKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKT 2476
+K + E+ SD + +++ L + A + + ++ L +
Sbjct: 2892 LLIKKLDTLQTEIAGRSDAVVEMMKKARELRVQGSAAADDCLKQA--EQVEARYSGLDEP 2949
Query: 2475 TTEKSYRLKEANKQKSFM-AAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEA 2299
+ L +A ++ AA +DLE WL + +L S + G L S +L KKH+ LE
Sbjct: 2950 VQIRRENLVDAQAFFQWVKAAEEDLE-WLSDRMMLASSGESGDSLQSALSLQKKHATLEK 3008
Query: 2298 DIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALN 2119
++ Q + + ++ ++ F I + ++ +K+ RRD L +A++
Sbjct: 3009 ELDTRQSAMNDTEQRGKDMIRQRHFASTHIQKILDRLSSAMLTLKESCGLRRDLLQEAID 3068
Query: 2118 VHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKL 1939
H+++ + + E W++E+ L S + GRD G ++ R+ +D E+ + ++ +K
Sbjct: 3069 AHEYYTEETEAEQWLREQMPLAMSQEMGRDQAGAESHLRRLTVLDKEVELFKNEIDRLKK 3128
Query: 1938 KGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEE 1759
+ + LL + I + LE +G + R ++ ++ + F+ ++
Sbjct: 3129 RADGLLAREHHDAM---SIAAKQRKLEALFGDLCRECARRRTQIVDASKYHKFVRQADDL 3185
Query: 1758 EAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNH 1579
W+ EK++ ++++G+++ Q ++++ ++ +L +RVA + + L+ +G+
Sbjct: 3186 SDWLREKERSASAEDYGQDLEDCQQIIEQFESTVRELAAAGERVAAVQRAQEDLLRSGHP 3245
Query: 1578 HAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQ---QV 1408
+ I + ++ + +A R L +F + D + +W+ +KE +
Sbjct: 3246 YGASITAKGADVQRLWTHVNEVANERKQALNGARQVHRFDQEADQILNWLQDKEATGVAM 3305
Query: 1407 RSEDFGR-DLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRH 1231
ED R DL+SV+ L + + F G+ A E + + + ++L +S +E R
Sbjct: 3306 EQEDLSRADLASVKAQLQRHDEFMHGMKAVEKQ-VAELCHEAERLWNSFPDTRHHLEVRR 3364
Query: 1230 TNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPV 1051
++ ++ +++L ++ +E W +N + +T
Sbjct: 3365 LDMEEQLKDILEAAKKHLEKLRHMQSLQSYFQEY--------REMMQWMKNMQSTMTSEQ 3416
Query: 1050 RCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDT 871
+ +L H E+ + + RR+ + + +D LE +
Sbjct: 3417 LPRDVASCESLVRRHDEYNLEMQGRKPFVDDFARQGRRMIQSSHVLSQEIQEKVDILEKS 3476
Query: 870 WRNLQRIIKEREQ------ELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEMMEAG 709
W L I K+R + ++ + Q E+ D E A L W EM E
Sbjct: 3477 WAMLCEIWKDRAELYEENMDVQKWKQNAEQLDSWLEERAGLLG--DDWRMVDSVEMAETH 3534
Query: 708 --------GTLEEQLDAVE--RKAKEIKANKGQLRQIEEKGAMLERNLILDNRYTEHSTV 559
TLE Q + + ++ ++ N +LR E ++R I ++ T+
Sbjct: 3535 LRDFDDFLVTLEAQSEKCDMVKRLTLVEQNFSRLRSKE-----IDRARIAEDDQKRRDTI 3589
Query: 558 GIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMMFKHFDKEKT 403
I + + L + Q+I S EE + D+ KT
Sbjct: 3590 KIVEKGNILANRRQERERRKTQEISLLRPSPSGEEFSTHTMPRKERKDRAKT 3641
Score = 469 bits (1208), Expect = e-130
Identities = 424/2072 (20%), Positives = 872/2072 (41%), Gaps = 64/2072 (3%)
Frame = -1
Query: 7200 ADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEEN 7021
AD IH ++L Y+ K +Q ++ L+E+R + D D WI EK A ++
Sbjct: 1550 ADRIHSTVGQLLQRYAAMKGPAQRRKGDLDESRLWHQLVFDVDCELQWIAEKKPIASSQD 1609
Query: 7020 F-RDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHAL 6844
R + ++K E EAEV H I + +I+ +H AS IK + EL
Sbjct: 1610 CGRTLTEALNMVKKQEQLEAEVNQHGGQIDKVLLQAGELIKRHHSASSQIKAKSSELETA 1669
Query: 6843 WXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRK 6664
W + + +K ++ E+ W+ EK + +ED G D + L K
Sbjct: 1670 WSELKKLLRLRRAVVDWGVKEQQYLFDAAEVESWMNEKRNALASEDYGNDEDAARKLLSK 1729
Query: 6663 FDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEG 6484
+++ ++ + ++ +LVE ++ K++D++ + L+ LA R+
Sbjct: 1730 HRALCEDMTTYRQWLEKLEVKCVELVESNRPHVERFQKRQDELVREFDALSKLAEDRRNA 1789
Query: 6483 LFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGK 6304
L A + + R++ + I E S+++ D +++ LQ K + ++ + +
Sbjct: 1790 LEDAVCLYEYMRESADLGQSIEENLRVAMSEEFAEDYEHLKELQSKFDEFKQKVKNGSER 1849
Query: 6303 MLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADY 6124
E A+ + +P A + +K + + AWN L E + R L + +LHRF D
Sbjct: 1850 FTSCETAANAILRRNPPFARDVVKKQEALRTAWNTLCEYIEARDSKLAVAEELHRFHRDV 1909
Query: 6123 RDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEI---DARADSFNQTASAGQKL 5953
+ W+ D A + D L +DV +L + H+ EI R + A +K
Sbjct: 1910 DEFEQWMADKMANMPRD-LGRDVKHVHSLWQHHEALDKEIHNSQPRLAKLVEEAERLKKT 1968
Query: 5952 VEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQE 5773
G E ++ + + L+ E L ++R+ + DL F W +
Sbjct: 1969 YPGGNAE--QIGGRQQTLEQEWEELKNATDDRKDMLRAAFDLHTFNGKVRDLLAWTDLTI 2026
Query: 5772 AFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEX 5593
+ + + + L E L +H + A+E + L K+I QHYA++++
Sbjct: 2027 SDIQSDLHINDLQQAEWLQTEHSRLSHEMDAREPEFARLVNDGEKMITAQHYASEEIKNK 2086
Query: 5592 XXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSY-LDPTN 5416
R L ++ + F R+ ++++ I K +T R + +
Sbjct: 2087 THLLKSALERLRSEWALRNGFLSQAVQWHAFQREAKQIIASIGSKRTTLRSLAVGGSVAD 2146
Query: 5415 IRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDA 5236
+ + ++ FE+ L + R + T +++ + H + +I V+ L
Sbjct: 2147 VESQTKRLDTFEKALSTLDERTATLDHTANELMKARHMESKNISMWQSNVHEELKLLRQD 2206
Query: 5235 TNKKGAKLREAGNEQQFNRNIEDVEAWLSE-LEGQVASEDYGKDLVSVQNLQKKI---GL 5068
+ A L++A F+ ++ +EAW+ E G ++D + +S+ K++
Sbjct: 2207 IEARHAMLKDAFALASFDSDVAQIEAWIDEKTNGVRKAQDLSSESISIDEKMKRLQTHQA 2266
Query: 5067 IESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGE 4888
+E++ A+ VD I Q Q + H N P I + + L ++N L + L E
Sbjct: 2267 LEAEVTANKPVVDQILQRGNQL-KNLHRN-PKIANRCDELSYKWNQLSGACADQSLALEE 2324
Query: 4887 SHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIES 4708
+ + + +E+ LAWI EKE + + + G+D+ + L+++ ++ + ++
Sbjct: 2325 ARDLLRFKQLVENVLAWINEKEVLVSTADMGKDMEHCRLLLERLDGTRSDSIVDEQTLDE 2384
Query: 4707 VSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEA 4528
++ +++QG +++ + L + WR+L + RT+L +++ H + D +
Sbjct: 2385 INRLGEKLVKQGRSSRDQVQKEQQHLNEKWRLLLGQLAHYRTELLAAMEVHTFNRDVEDT 2444
Query: 4527 DAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQP 4348
D + EK + S DYGKD S E L++K AL D+ A + K A + + P
Sbjct: 2445 DERIHEKVAAMKSDDYGKDFASVELLVRKQSALERDMSAIHQKLIAHDKDAQKILEKRPP 2504
Query: 4347 MGQLGRDCVLALYDYQEKSPREVSMKKGDV-------LTLLNASNRDWWKVEVNDRQGFV 4189
+ + D + L + E+ + ++ + L + + W +V ++
Sbjct: 2505 LRETVLDSLKKLEESWEQLSKAAELRNEKLNRSFKLYKYLDDVKKVEQWANQVRNKMTSH 2564
Query: 4188 PAAYVKRIEPGTAQQHAQQQVNSIGGKQSE----------------------------IE 4093
+QH +++ I G+ E ++
Sbjct: 2565 QTPKDSNGARKILEQHHERKA-EIDGRSEELRLLHEEGQALNQEQPEHKAEVQRAHKRVQ 2623
Query: 4092 DKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQ 3913
+ +L E+ K L++ + EA +W+ +E A+ E+G + VE+L
Sbjct: 2624 NSEHQLRQTWESEKGTLQKLLEWMLWCDEAVQCEQWLSDKETQVARGELGDTTDAVEMLI 2683
Query: 3912 KKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXX 3733
K F+ ++ ++ + + A AL S G A I + E++ AR L
Sbjct: 2684 KGHSAFEETVRKQSEKIDALTKNADALVSGGNNYRA-DIVTRSEEVTARHALLLKSMEKR 2742
Query: 3732 XXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAAL 3553
L + + F R E WI K E F D ++++ +KH + +L
Sbjct: 2743 GHMLEDSKKYHEFIRQCGELIIWITAKLQLAYDESF-LDHTNLRSKLQKHMAFDSELVEN 2801
Query: 3552 GDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFL 3373
++ +++ + +L + +EQ+ EL W+ L +K+ + ++L ++++
Sbjct: 2802 EKRLSTVERQGEQLVTDNHFMSEQVKAQLVELRSGWDELRTKSALKTQRLREAFELHSLQ 2861
Query: 3372 SDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQL 3193
D+ +W+ + +SS + D+ E L+++ +TEI R+ + +L
Sbjct: 2862 RKVEDIEKWLDKVEGELSSDDHGRDILSTELLIKKLDTLQTEIAGRSDAVVEMMKKAREL 2921
Query: 3192 LNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSARE 3013
AA D + + V GL++ RR L + + E+ W+S R
Sbjct: 2922 RVQGSAAADDCLKQAEQVEARYSGLDEPVQIRRENLVDAQAFFQWVKAAEEDLEWLSDR- 2980
Query: 3012 AFLAQEDPSGDNVE---SLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTR 2842
LA SGD+++ SL KKH +K ++T++ + + + +I+ H+ S + +
Sbjct: 2981 MMLASSGESGDSLQSALSLQKKHATLEKELDTRQSAMNDTEQRGKDMIRQRHFASTHIQK 3040
Query: 2841 KRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIA-QEENYRDPT 2665
D++ LKE+ +R L E+ ++ + E E W+ E+ +A +E RD
Sbjct: 3041 ILDRLSSAMLTLKESCGLRRDLLQEAIDAHEYYTEETEAEQWLREQMPLAMSQEMGRDQA 3100
Query: 2664 NIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLL 2485
+ ++ + E+ + I + + + L+ A+ +++A+ + L + L
Sbjct: 3101 GAESHLRRLTVLDKEVELFKNEIDRLKKRADGLL--AREHHDAMSIAAKQRKLEALFGDL 3158
Query: 2484 VKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLL 2305
+ + ++ +A+K F+ DL WL E E +EDYG+DL + ++++
Sbjct: 3159 CRECARRRTQIVDASKYHKFVRQADDLSDWLREKERSASAEDYGQDLEDCQQIIEQFEST 3218
Query: 2304 EADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKA 2125
++ A +RV + + LL + G I + + + V ++A +R+ L+ A
Sbjct: 3219 VRELAAAGERVAAVQRAQEDLLRSGHPYGASITAKGADVQRLWTHVNEVANERKQALNGA 3278
Query: 2124 LNVHQFFRDIDDEESWIKEKK---LLVSSDDYGR-DLPGVQNLRRKHRRIDTELASHEPQ 1957
VH+F ++ D +W+++K+ + + +D R DL V+ ++H + + E Q
Sbjct: 3279 RQVHRFDQEADQILNWLQDKEATGVAMEQEDLSRADLASVKAQLQRHDEFMHGMKAVEKQ 3338
Query: 1956 VSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFL 1777
V+ + + E L S + ++ R D+E+ I + ++L ++ Q++
Sbjct: 3339 VAELCHEAERLWNSFPDT---RHHLEVRRLDMEEQLKDILEAAKKHLEKLRHMQSLQSYF 3395
Query: 1776 GDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTL 1597
+ E WM Q + S+ ++A + L+++HD + ++++ K V D +G +
Sbjct: 3396 QEYREMMQWMKNMQSTMTSEQLPRDVASCESLVRRHDEYNLEMQGRKPFVDDFARQGRRM 3455
Query: 1596 IHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKE 1417
I + + + I+++ D L + + + R +N ++ + ++SW+ E+
Sbjct: 3456 IQSSHVLSQEIQEKVDILEKSWAMLCEIWKDRAELYEENMDVQKWKQNAEQLDSWLEERA 3515
Query: 1416 QQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEG-----IQRITELK---DQLVSSEH 1261
+ D R + SV++ T FD L E + ++R+T ++ +L S E
Sbjct: 3516 GLL--GDDWRMVDSVEMAETHLRDFDDFLVTLEAQSEKCDMVKRLTLVEQNFSRLRSKEI 3573
Query: 1260 QQSPAIE----KRHTNVIQRWQNLLAHSEARR 1177
++ E +R T I N+LA+ R
Sbjct: 3574 DRARIAEDDQKRRDTIKIVEKGNILANRRQER 3605
Score = 400 bits (1027), Expect = e-109
Identities = 461/2359 (19%), Positives = 966/2359 (40%), Gaps = 113/2359 (4%)
Frame = -1
Query: 7221 EIRILETADDIHQRRQE---VLGHYSIFKDHSQTKRDRLEEARQFQY------------- 7090
EI L A+D+ R + ++ + S++ H ++ + AR+
Sbjct: 266 EIARLLDAEDVDVTRPDEKSIITYVSLYYHHFAKQKTEMTGARRIANIVGKLMVSETMED 325
Query: 7089 -FKRDADELNVWILEKLQTAQEENFRDPSNLQAKIQKHEAF--------------EAEVQ 6955
++ A EL WI ++T + F P++L ++H F + E++
Sbjct: 326 DYEHIASELLNWIRVTIKTLESRRF--PNSLNGMREEHAKFNQFRTSEKPPKYKEKGELE 383
Query: 6954 AHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKLLH 6775
A TI K AM + + + + + ++ + W + + + L+
Sbjct: 384 ALFFTIQTKRK---AMSRKQYQPPQGLF--MHDIESAWAQLDYAENERQVAIIAELQRQE 438
Query: 6774 FIRQCDEILY--------WIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRI 6619
+ Q + + W+R + + + G VE +K ++ + R
Sbjct: 439 KLEQLAQRFHKKAKLRDSWLRSVQVVLEEMEHGRSASQVEKTLKKQQAISTDILAREDRF 498
Query: 6618 NEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDAD 6439
+ ++L E + E D++ ++ D W +L TL RK L + + RD D
Sbjct: 499 KMLTAMCNELCTEKYHESDKVRGMEREIIDRWTQLLTLLEQRKRALMSLNDLMSLLRDID 558
Query: 6438 ETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETH 6259
+ + A+ + D G+ L V+ L KH+ + + A + +L + A+
Sbjct: 559 TLSNELYSLEPAVRNRDVGKHLIGVEDLLGKHDLLDAQINAHGSLLSKLSQSANNYIRHK 618
Query: 6258 PDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIG 6079
++ + + +K D+ A +N L E + R+ GLER+ L +F+ D+ + ++W+ + + +
Sbjct: 619 EEQFDVLQRKLDEVTAQYNTLVELCRSRRLGLERARSLFQFVQDHEEEMAWLAEKEKLCT 678
Query: 6078 ADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKL 5899
+ D++ ++ + E+ + G++LV+ G ++Q +L ++
Sbjct: 679 TALNSGDISAVPQTTLLYKNVEMEMQTHWARSKGMIAGGERLVQNG-QSKEDIQRRLTQM 737
Query: 5898 DHEKSSLLGLWEERRILYE-------QCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDS 5740
+H WE R+ + + Q +++D +AE+W+ ++ + + DLG
Sbjct: 738 NHR-------WERLRVAVDALGNWLSEARHAQQYFQDANEAESWIREKMPLVKSDDLGRD 790
Query: 5739 LDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXX 5560
+ E L+++H E+ + A + I+ L+E ++L + A
Sbjct: 791 EGAAESLLQRHARLEEEIRAYKSDISRLEEMQSQLANSAFHTATTSQSVQETEEVNVPQV 850
Query: 5559 XXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFE 5380
GN ++ S V + EK ST L G + N+
Sbjct: 851 EMSYNYEGNGMRVSKGE----------VLALLEK-STPEWWRALKRDGTEGYVP--ANYC 897
Query: 5379 QELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAG 5200
+ + + ++ + + DR +++N + EL + + L +
Sbjct: 898 KIVPGETVTVTQTTQKTTTTLEGNETKSSVVADRQHKISNDYRELKRLADVRRRLLSDNI 957
Query: 5199 NEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAH-NDRVDGI 5023
+F R ++ E W E+E +A E + + + ++K +E+D + ++ I
Sbjct: 958 KLLRFYRECDEFERWAKEIEVSLADEPSPEHVAA---FRRKFDKLEADMKTNGGTQLKHI 1014
Query: 5022 KQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDI---- 4855
+A E H + RK E Q + NA+ D LE+ +++ G + + D
Sbjct: 1015 NDIANDLISEGHGQS----RKIEVRQHKINAMWDNLERLRKQRGVRLEATERVADFDTTC 1070
Query: 4854 EDELAWIREK-EQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQ 4678
E W+ K EQ+ + N D+ +QNL + + L +IA +E +++A ++
Sbjct: 1071 ESAREWMLSKFEQLDRNPN---DVKSLQNLERDLKPLEDKIA----ALEKLAAA----VK 1119
Query: 4677 QGH-FLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEP 4501
+ H A I K+A+LR L +A+++ + + + S + W+ +
Sbjct: 1120 KDHPEEAAAIERKIAELRALHADLLRRAQEKMLLAEQTQGKEMFESALRDMIGWIEKTRK 1179
Query: 4500 IVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIED--------LRKQASQCKYQEQPM 4345
++ + D AE LLKKH L ++ K +E L + K +EQ
Sbjct: 1180 VMMEDVHPVDVAEAEELLKKHYELGEQIKDKKYEVEYCQELGRRLLERNPRMSKVEEQLQ 1239
Query: 4344 GQLG-----------RDCVLA----LYDYQEKSPREVSMKKG------------DVLTLL 4246
+ RD +L L + +S R + KG V ++
Sbjct: 1240 NLVSEMASLRDLYRRRDTILKQQLDLQLFNRESERIDAATKGHEAFLEFDNLGDSVESVE 1299
Query: 4245 NASNRDWWKVEVNDRQGFVPAAYVKRIEPGTAQQHAQQQVNSIGGKQSEIEDKYQRLMML 4066
N R D Q A+ + + QHA I ++ ++ + + +
Sbjct: 1300 NLLKRHRDLEAKLDAQEARLEAFSRTADDMIKAQHADSAY--IEQRRRDVLARREAVRRA 1357
Query: 4065 GETRKRKLEEACKGYQLLREANDLAEWI-KSREAVAAQQEIGTDLEQVEVLQKKFDDFKG 3889
RK++LE + + ++ REA+++ W+ + + V + + + K + F+
Sbjct: 1358 AAQRKKQLEASLEYQEMRREADEVVGWMYEKAKLVMSGDDSALAPSAIPHRLLKHEAFEA 1417
Query: 3888 DLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAH 3709
++ ANE R+Q++N L S E+ + + + +NA+W L +L A
Sbjct: 1418 EIIANEPRIQQINSEGDGLVSKKHYESP-NVEKIVRQVNAQWGDLKKQVWNKGLRLRQAA 1476
Query: 3708 EVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLD 3529
+ + R +++ + E AL+S+D G DLRSV+ L +KH +E+++ G+K+ ++
Sbjct: 1477 DQKGLDRILEDAHAKLDEMQTALNSKDQGLDLRSVKDLLQKHAVLEQEMGLYGNKLSDIE 1536
Query: 3528 EKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQ 3349
+ ++ A++I+ +L +++ + A RK L +S + + + D +Q
Sbjct: 1537 NRGKKMAVDGHYDADRIHSTVGQLLQRYAAMKGPAQRRKGDLDESRLWHQLVFDVDCELQ 1596
Query: 3348 WIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAA 3169
WIA + SSQ+ +T A ++++ ++ E++ +L+ HH A+
Sbjct: 1597 WIAEKKPIASSQDCGRTLTEALNMVKKQEQLEAEVNQHGGQIDKVLLQAGELIKRHHSAS 1656
Query: 3168 GDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDP 2989
I+ + + A L+ RR ++D ++ Q + D + ++WM+ + LA ED
Sbjct: 1657 SQIKAKSSELETAWSELKKLLRLRRAVVDWGVKEQQYLFDAAEVESWMNEKRNALASEDY 1716
Query: 2988 SGDN--VESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRW 2815
D L+ KH + + T + ++ L++ L+++N +++D+++ +
Sbjct: 1717 GNDEDAARKLLSKHRALCEDMTTYRQWLEKLEVKCVELVESNRPHVERFQKRQDELVREF 1776
Query: 2814 NGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENY-RDPTNIQQKHQKQ 2638
+ L + +R L ++ L ++ R++ ++ + E ++A E + D ++++ K
Sbjct: 1777 DALSKLAEDRRNALEDAVCLYEYMRESADLGQSIEENLRVAMSEEFAEDYEHLKELQSKF 1836
Query: 2637 QAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSY 2458
F+ ++ S+R + A N ++ + V + +AL W+ L + +
Sbjct: 1837 DEFKQKVKNGSERFTSCETAANAILRRNPPFARD--VVKKQEALRTAWNTLCEYIEARDS 1894
Query: 2457 RLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQD 2278
+L A + F V + E W+ + ++ D G+D+ V +L + H L+ +I Q
Sbjct: 1895 KLAVAEELHRFHRDVDEFEQWMAD-KMANMPRDLGRDVKHVHSLWQHHEALDKEIHNSQP 1953
Query: 2277 RVGEMNEQADSLLEN-DQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFR 2101
R+ ++ E+A+ L + +QI R++ + ++ +K DR+D L A ++H F
Sbjct: 1954 RLAKLVEEAERLKKTYPGGNAEQIGGRQQTLEQEWEELKNATDDRKDMLRAAFDLHTFNG 2013
Query: 2100 DIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELL 1921
+ D +W + SD + DL + L+ +H R+ E+ + EP+ + + GE+++
Sbjct: 2014 KVRDLLAWTDLTISDIQSDLHINDLQQAEWLQTEHSRLSHEMDAREPEFARLVNDGEKMI 2073
Query: 1920 RSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNE 1741
+ A ++IK + L+ + ++R R+ L ++ + AF + ++ A +
Sbjct: 2074 TAQHYA---SEEIKNKTHLLKSALERLRSEWALRNGFLSQAVQWHAFQREAKQIIASIGS 2130
Query: 1740 KQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIK 1561
K+ L S G ++A V+ K+ DTF+ L +R A L + + L+ + + +I
Sbjct: 2131 KRTTLRSLAVGGSVADVESQTKRLDTFEKALSTLDERTATLDHTANELMKARHMESKNIS 2190
Query: 1560 QRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDL 1381
+ L + E R A L+D A F +E+WI EK VR +DL
Sbjct: 2191 MWQSNVHEELKLLRQDIEARHAMLKDAFALASFDSDVAQIEAWIDEKTNGVRK---AQDL 2247
Query: 1380 SSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQ-----QSPAIEKRHTNVIQ 1216
SS I + ++ A E E + + DQ++ +Q ++P I R +
Sbjct: 2248 SSESISIDEKMKRLQTHQALEAE-VTANKPVVDQILQRGNQLKNLHRNPKIANRCDELSY 2306
Query: 1215 RWQNL--------LAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLT 1060
+W L LA EAR L F + +W E ++
Sbjct: 2307 KWNQLSGACADQSLALEEARD----------------LLRFKQLVENVLAWINEKEVLVS 2350
Query: 1059 DPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDAL 880
+E R L + + E+ ++ L ++ L
Sbjct: 2351 TADMGKDMEHCRLLLERLDGTRSDSIVDEQTLDEINRLGEKLVKQGRSSRDQVQKEQQHL 2410
Query: 879 EDTWRNLQRIIKEREQELAR-------EHQRQEENDKLRREFAKLANAFHAWLTNTRQEM 721
+ WR L + EL ++ ++++ + A + + + + + +
Sbjct: 2411 NEKWRLLLGQLAHYRTELLAAMEVHTFNRDVEDTDERIHEKVAAMKSDDYGKDFASVELL 2470
Query: 720 MEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERNLILDNRYTEHSTVGIAQAW 541
+ LE + A+ +K + A+ ++I EK L R +LD S + ++W
Sbjct: 2471 VRKQSALERDMSAIHQK---LIAHDKDAQKILEKRPPL-RETVLD------SLKKLEESW 2520
Query: 540 DQLDQLAMRMQHNLEQQIQ 484
+QL + A L + +
Sbjct: 2521 EQLSKAAELRNEKLNRSFK 2539
Score = 394 bits (1011), Expect = e-107
Identities = 463/2289 (20%), Positives = 934/2289 (40%), Gaps = 88/2289 (3%)
Frame = -1
Query: 7200 ADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELN--VWILEKLQTAQE 7027
+D + +E++ ++ + ++ L RD D L+ ++ LE ++
Sbjct: 516 SDKVRGMEREIIDRWTQLLTLLEQRKRALMSLNDLMSLLRDIDTLSNELYSLEPAVRNRD 575
Query: 7026 ENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHA 6847
+ ++ + KH+ +A++ AH ++ L ++ N I+H + ++++L+E+ A
Sbjct: 576 VG-KHLIGVEDLLGKHDLLDAQINAHGSLLSKLSQSANNYIRHKEEQFDVLQRKLDEVTA 634
Query: 6846 LWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQR 6667
+ + + L++A L F++ +E + W+ EKE T D+ V
Sbjct: 635 QYNTLVELCRSRRLGLERARSLFQFVQDHEEEMAWLAEKEKLCTTALNSGDISAVPQTTL 694
Query: 6666 KFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKE 6487
+ + E+ H R + ++LV+ G S+ D I ++ +N W RL
Sbjct: 695 LYKNVEMEMQTHWARSKGMIAGGERLVQNGQSKED-IQRRLTQMNHRWERLRVAVDALGN 753
Query: 6486 GLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEG 6307
L A Q++ +DA+E +WI EK + SDD GRD ++L ++H E ++ A +
Sbjct: 754 WLSEARHAQQYFQDANEAESWIREKMPLVKSDDLGRDEGAAESLLQRHARLEEEIRAYKS 813
Query: 6306 KMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLAD 6127
+ +LE+ +LA + A H T +++E + +E S+ +
Sbjct: 814 DISRLEEMQSQLANS------AFH-----TATTSQSVQETEEVNVPQVEMSYNY-----E 857
Query: 6126 YRDLISWIGDMKAVIGADE------LAKDVAGAEALLESHQEHKGEIDARADSFNQTASA 5965
+ G++ A++ L +D G E + ++ + + + QT
Sbjct: 858 GNGMRVSKGEVLALLEKSTPEWWRALKRD--GTEGYVPAN--YCKIVPGETVTVTQTTQK 913
Query: 5964 GQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWM 5785
+E +S V ++ K+ ++ L L + RR L + L FYR+ ++ E W
Sbjct: 914 TTTTLEGNETKSSVVADRQHKISNDYRELKRLADVRRRLLSDNIKLLRFYRECDEFERWA 973
Query: 5784 NKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQE----EKINALDEFATKLIQGQHY 5617
+ E LA+ S EH+ F+K A + ++ +++ A LI H
Sbjct: 974 KEIEVSLADE------PSPEHVAAFRRKFDKLEADMKTNGGTQLKHINDIANDLISEGHG 1027
Query: 5616 AADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDD 5437
+ + RG L+ + + FD C+ W+ K +
Sbjct: 1028 QSRKIEVRQHKINAMWDNLERLRKQRGVRLEATERVADFDTTCESAREWMLSKF----EQ 1083
Query: 5436 SYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNL 5257
+P +++ LQ N E++LK E+++ + + A I ++ ++ L
Sbjct: 1084 LDRNPNDVK-SLQ---NLERDLKPLEDKIAALEKLAAAVKKDHPEEAAAIERKIAELRAL 1139
Query: 5256 WNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKK 5077
+L+ +K + ++ F + D+ W+ + + + + D+ + L KK
Sbjct: 1140 HADLLRRAQEKMLLAEQTQGKEMFESALRDMIGWIEKTRKVMMEDVHPVDVAEAEELLKK 1199
Query: 5076 IGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRK 4897
+ V+ ++L ++ E + + +NL +LRD L +R+
Sbjct: 1200 HYELGEQIKDKKYEVEYCQELGRRLLERNP-RMSKVEEQLQNLVSEMASLRD-LYRRRDT 1257
Query: 4896 LGESHQGNQLF-RDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDS 4720
+ + QLF R+ E A + E N G + V+NL+K+ + L A++ ++
Sbjct: 1258 ILKQQLDLQLFNRESERIDAATKGHEAFLEFDNLGDSVESVENLLKRHRDLEAKLDAQEA 1317
Query: 4719 QIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSD 4540
++E+ S A+DMI+ H + I + + ++ A +R+ L+ SL+ + +
Sbjct: 1318 RLEAFSRTADDMIKAQHADSAYIEQRRRDVLARREAVRRAAAQRKKQLEASLEYQEMRRE 1377
Query: 4539 ANEADAWMSEKEPIVGSTDYGKDEDSA-EALLKKHRALLSDLEAFKGTIEDLRKQ----A 4375
A+E WM EK +V S D SA L KH A +++ A + I+ + +
Sbjct: 1378 ADEVVGWMYEKAKLVMSGDDSALAPSAIPHRLLKHEAFEAEIIANEPRIQQINSEGDGLV 1437
Query: 4374 SQCKYQEQPMGQLGRDCVLALYDYQEK------SPREVSMKKGDVLTLLNA-SNRDWWKV 4216
S+ Y+ + ++ R D +++ R+ + +KG L +A + D +
Sbjct: 1438 SKKHYESPNVEKIVRQVNAQWGDLKKQVWNKGLRLRQAADQKGLDRILEDAHAKLDEMQT 1497
Query: 4215 EVNDRQGFVPAAYVKRIEPGTAQQHA--QQQVNSIGGKQSEIEDKYQRLMMLG------- 4063
+N + + VK + Q+HA +Q++ G K S+IE++ +++ + G
Sbjct: 1498 ALNSKDQGLDLRSVKDL----LQKHAVLEQEMGLYGNKLSDIENRGKKMAVDGHYDADRI 1553
Query: 4062 ------------------ETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTD 3937
+ RK L+E+ +QL+ + + +WI ++ +A+ Q+ G
Sbjct: 1554 HSTVGQLLQRYAAMKGPAQRRKGDLDESRLWHQLVFDVDCELQWIAEKKPIASSQDCGRT 1613
Query: 3936 LEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQT-----ETAVRIRQQIEDLN 3772
L + + KK + + ++ Q QI L G+ + +I+ + +L
Sbjct: 1614 LTEALNMVKKQEQLEAEVN------QHGGQIDKVLLQAGELIKRHHSASSQIKAKSSELE 1667
Query: 3771 ARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQ 3592
W L + + Q++ D E W+ EK +AL SED+G D + + L
Sbjct: 1668 TAWSELKKLLRLRRAVVDWGVKEQQYLFDAAEVESWMNEKRNALASEDYGNDEDAARKLL 1727
Query: 3591 RKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRK 3412
KH + D+ ++ L+ K L +S+ E+ Q EL +++ L+ A +R+
Sbjct: 1728 SKHRALCEDMTTYRQWLEKLEVKCVELVESNRPHVERFQKRQDELVREFDALSKLAEDRR 1787
Query: 3411 EKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRA 3232
L D+ ++ + DL Q I ++ S+E A D + L + E++ ++ + +
Sbjct: 1788 NALEDAVCLYEYMRESADLGQSIEENLRVAMSEEFAEDYEHLKELQSKFDEFKQKVKNGS 1847
Query: 3231 ATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYR 3052
F + + N +L + A D+ + + + A L + AR + L EL F+R
Sbjct: 1848 ERFTSCETAANAILRRNPPFARDVVKKQEALRTAWNTLCEYIEARDSKLAVAEELHRFHR 1907
Query: 3051 DCEQADTWMSAREAFLAQE-DPSGDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIK 2875
D ++ + WM+ + A + ++ +V SL + HE DK I+ + ++ L AE L K
Sbjct: 1908 DVDEFEQWMADKMANMPRDLGRDVKHVHSLWQHHEALDKEIHNSQPRLAKLVEEAERLKK 1967
Query: 2874 NNHYDSPAVTRKRDQILDR-WNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQ 2698
+ R Q L++ W LK A ++ L + L F+ ++ W
Sbjct: 1968 TYPGGNAEQIGGRQQTLEQEWEELKNATDDRKDMLRAAFDLHTFNGKVRDLLAWTDLTIS 2027
Query: 2697 IAQEE-NYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEA---- 2533
Q + + D + + E+ A A ++ G +I E
Sbjct: 2028 DIQSDLHINDLQQAEWLQTEHSRLSHEMDAREPEFARLVNDGEKMITAQHYASEEIKNKT 2087
Query: 2532 -AVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDY 2356
+ + L+ L +W L ++ L +A + +F K + +G L+S
Sbjct: 2088 HLLKSALERLRSEWAL-------RNGFLSQAVQWHAFQREAKQIIASIGSKRTTLRSLAV 2140
Query: 2355 GKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRY 2176
G +A VE+ K+ E + +R ++ A+ L++ + + I+ + + +
Sbjct: 2141 GGSVADVESQTKRLDTFEKALSTLDERTATLDHTANELMKARHMESKNISMWQSNVHEEL 2200
Query: 2175 DGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLV-SSDDYGRDLPGVQNLRRK 1999
+++ R L A + F D+ E+WI EK V + D + + ++
Sbjct: 2201 KLLRQDIEARHAMLKDAFALASFDSDVAQIEAWIDEKTNGVRKAQDLSSESISIDEKMKR 2260
Query: 1998 ---HRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLT 1828
H+ ++ E+ +++P V + +G +L +I R ++L W Q+
Sbjct: 2261 LQTHQALEAEVTANKPVVDQILQRGNQLKNLHR-----NPKIANRCDELSYKWNQLSGAC 2315
Query: 1827 GNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDL 1648
++ L+E+ F VE AW+NEK+ ++ + + G++M + LL++ D + D
Sbjct: 2316 ADQSLALEEARDLLRFKQLVENVLAWINEKEVLVSTADMGKDMEHCRLLLERLDGTRSDS 2375
Query: 1647 ELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDN--SA 1474
+ +Q + ++ G+ L+ G +++ + L E + G+LA R +A
Sbjct: 2376 IVDEQTLDEINRLGEKLVKQGRSSRDQVQKE----QQHLNEKWRLLLGQLAHYRTELLAA 2431
Query: 1473 YLQFMWKCDV--VESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGI-- 1306
+ DV + I EK ++S+D+G+D +SV++L+ KQ A + ++A + I
Sbjct: 2432 MEVHTFNRDVEDTDERIHEKVAAMKSDDYGKDFASVELLVRKQSALERDMSAIHQKLIAH 2491
Query: 1305 ----QRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQI 1138
Q+I E + L + +E + W+ L +E R
Sbjct: 2492 DKDAQKILEKRPPLRETVLDSLKKLE-------ESWEQLSKAAELRNEKLNRSFKLYK-- 2542
Query: 1137 EELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQ 958
YL KK W +T R + + H E + + E+ R
Sbjct: 2543 ---YLDDVKKV---EQWANQVRNKMTSHQTPKDSNGARKILEQHHERKAEIDGRSEELRL 2596
Query: 957 LQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRRE 778
L + + + ++ + + + ++ EHQ ++ + +
Sbjct: 2597 LHEEGQALN-----------------QEQPEHKAEVQRAHKRVQNSEHQLRQTWESEKGT 2639
Query: 777 FAKL---------ANAFHAWLTNTRQEMMEAGGTLEEQLDAVERKAKEIKANKGQLRQIE 625
KL A WL++ +E A G L + DAVE K A + +R+
Sbjct: 2640 LQKLLEWMLWCDEAVQCEQWLSD--KETQVARGELGDTTDAVEMLIKGHSAFEETVRKQS 2697
Query: 624 EKGAMLERN 598
EK L +N
Sbjct: 2698 EKIDALTKN 2706
Score = 179 bits (454), Expect = 9e-43
Identities = 263/1342 (19%), Positives = 521/1342 (38%), Gaps = 35/1342 (2%)
Frame = -1
Query: 4284 EVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIEPGTAQQHAQQQVNSIGGKQ 4105
+V+ KK ++ LL+A + D + + +V Y + T A++ N +G
Sbjct: 259 DVAEKKLEIARLLDAEDVDVTRPDEKSIITYVSLYYHHFAKQKTEMTGARRIANIVGK-- 316
Query: 4104 SEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQV 3925
+M+ ET + E A++L WI+ + L +
Sbjct: 317 ----------LMVSETMEDDYEHI---------ASELLNWIRVTIKTLESRRFPNSLNGM 357
Query: 3924 EVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIE--------DLNA 3769
KF+ F+ K + + E ++ ++ QT+ R+Q + D+ +
Sbjct: 358 REEHAKFNQFRTSEKPPKYK--EKGELEALFFTI-QTKRKAMSRKQYQPPQGLFMHDIES 414
Query: 3768 RWRALXXXXXXXXXQLGSAHE--------VQRFHRDVDETRDWIQEKDDALDSEDFGRDL 3613
W L + + + QRFH+ W++ L+ + GR
Sbjct: 415 AWAQLDYAENERQVAIIAELQRQEKLEQLAQRFHKKAKLRDSWLRSVQVVLEEMEHGRSA 474
Query: 3612 RSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLT 3433
V+ +K + + D+ A D+ K L N L ++++ ++RE+ ++W +L
Sbjct: 475 SQVEKTLKKQQAISTDILAREDRFKMLTAMCNELCTEKYHESDKVRGMEREIIDRWTQLL 534
Query: 3432 SKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYR 3253
+ RK L+ D L D L + S+ V ++++ + G E LL +H
Sbjct: 535 TLLEQRKRALMSLNDLMSLLRDIDTLSNELYSLEPAVRNRDVGKHLIGVEDLLGKHDLLD 594
Query: 3252 TEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCL 3073
+I++ + Q N + ++ +L V L + +RR L++
Sbjct: 595 AQINAHGSLLSKLSQSANNYIRHKEEQFDVLQRKLDEVTAQYNTLVELCRSRRLGLERAR 654
Query: 3072 ELQLFYRDCEQADTWMSAREAFLAQEDPSGD--NVESLIKKHEDFDKAINTQEEKIKGLK 2899
L F +D E+ W++ +E SGD V +++ + + T + KG+
Sbjct: 655 SLFQFVQDHEEEMAWLAEKEKLCTTALNSGDISAVPQTTLLYKNVEMEMQTHWARSKGMI 714
Query: 2898 LFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIEN 2719
E L++N + R+ Q+ RW L+ A+ L E++ QQ+ +DA+E E+
Sbjct: 715 AGGERLVQNGQ-SKEDIQRRLTQMNHRWERLRVAVDALGNWLSEARHAQQYFQDANEAES 773
Query: 2718 WMTEKFQIAQEENY-RDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGG 2542
W+ EK + + ++ RD + Q+ E E+ A I+ + + + L +A
Sbjct: 774 WIREKMPLVKSDDLGRDEGAAESLLQRHARLEEEIRAYKSDISRLEEMQSQLANSA---- 829
Query: 2541 GEAAVSARLKALNDQWDLLVKTTTEKSYRLKEAN---KQKSFMAAVKDLEFWLGEVEILL 2371
TT++ +E N + S+ + GEV LL
Sbjct: 830 -----------------FHTATTSQSVQETEEVNVPQVEMSYNYEGNGMRVSKGEVLALL 872
Query: 2370 QSEDYGKDLASVENLLKKHSLLEADIVAHQDR--------VGEMNEQADSLLENDQFQGQ 2215
+ K LK+ E + A+ + V + ++ + LE ++ +
Sbjct: 873 E-----KSTPEWWRALKRDG-TEGYVPANYCKIVPGETVTVTQTTQKTTTTLEGNETKSS 926
Query: 2214 QIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYG 2035
+A+R+ I++ Y +K++A RR LS + + +F+R+ D+ E W KE ++ ++
Sbjct: 927 VVADRQHKISNDYRELKRLADVRRRLLSDNIKLLRFYRECDEFERWAKEIEVSLA----- 981
Query: 2034 RDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGED-QIKKRMEDLE 1858
D P +++ R+ D A + ++ G G+ +I+ R +
Sbjct: 982 -DEPSPEHVAAFRRKFDKLEADMKTNGGTQLKHINDIANDLISEGHGQSRKIEVRQHKIN 1040
Query: 1857 QSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLL 1678
W + L R RL+ +E F E WM K + L D ++ +Q L
Sbjct: 1041 AMWDNLERLRKQRGVRLEATERVADFDTTCESAREWMLSKFEQL--DRNPNDVKSLQNL- 1097
Query: 1677 KKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRL 1498
+ DL+ + ++A L + + A I+++ +LRA ++ A+ ++
Sbjct: 1098 ------ERDLKPLEDKIAALEKLAAAVKKDHPEEAAAIERKIAELRALHADLLRRAQEKM 1151
Query: 1497 AKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGR-DLSSVQILLTKQEAFDAGLNAF 1321
F + WI EK ++V ED D++ + LL K +
Sbjct: 1152 LLAEQTQGKEMFESALRDMIGWI-EKTRKVMMEDVHPVDVAEAEELLKKHYELGEQIKDK 1210
Query: 1320 EHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQ 1141
++E ++ EL +L+ +++P + K V ++ QNL++ + R Q
Sbjct: 1211 KYE-VEYCQELGRRLL----ERNPRMSK----VEEQLQNLVSEMASLRDLYRRRDTILKQ 1261
Query: 1140 IEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFR 961
+L L F +++ ++ + E L +S+E + L H + + L + E
Sbjct: 1262 QLDLQL-FNRESERIDAATKGHEAFLEFDNLGDSVESVENLLKRHRDLEAKLDAQEARLE 1320
Query: 960 QL-QDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLR 784
+ D IK+ + D L ++R +R+++L + QE +R
Sbjct: 1321 AFSRTADDMIKAQHADSAYIEQRRRDVLARR-EAVRRAAAQRKKQLEASLEYQE----MR 1375
Query: 783 REFAKLANAFH--AWLTNTRQEMMEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAM 610
RE ++ + A L + + A + +L E EI AN+ +++QI +G
Sbjct: 1376 READEVVGWMYEKAKLVMSGDDSALAPSAIPHRLLKHEAFEAEIIANEPRIQQINSEGDG 1435
Query: 609 LERNLILDNRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMM 430
L ++ E + W L + L Q + + E+A + M
Sbjct: 1436 LVSKKHYESPNVEKIVRQVNAQWGDLKKQVWNKGLRLRQAADQKGLDRILEDAHAKLDEM 1495
Query: 429 FKHFDKEKTGRLDHQQFKSCLR 364
+ + G LD + K L+
Sbjct: 1496 QTALNSKDQG-LDLRSVKDLLQ 1516
Score = 137 bits (346), Expect = 3e-30
Identities = 150/735 (20%), Positives = 298/735 (40%), Gaps = 13/735 (1%)
Frame = -1
Query: 2523 ARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDL 2344
A+L ++ + + ++ +L++ ++ A ++D WL V+++L+ ++G+
Sbjct: 417 AQLDYAENERQVAIIAELQRQEKLEQLAQRFHKKAKLRDS--WLRSVQVVLEEMEHGRSA 474
Query: 2343 ASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVK 2164
+ VE LKK + DI+A +DR + + L + ++ + I DR+ +
Sbjct: 475 SQVEKTLKKQQAISTDILAREDRFKMLTAMCNELCTEKYHESDKVRGMEREIIDRWTQLL 534
Query: 2163 KMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRID 1984
+ R+ L ++ RDID + + + V + D G+ L GV++L KH +D
Sbjct: 535 TLLEQRKRALMSLNDLMSLLRDIDTLSNELYSLEPAVRNRDVGKHLIGVEDLLGKHDLLD 594
Query: 1983 TELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLD 1804
++ +H +S + +R E D ++++++++ + + +L +R L+
Sbjct: 595 AQINAHGSLLSKLSQSANNYIRHKEEQ---FDVLQRKLDEVTAQYNTLVELCRSRRLGLE 651
Query: 1803 ESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVA 1624
+ + F+ D EEE AW+ EK+++ + +++ V + +++++ H R
Sbjct: 652 RARSLFQFVQDHEEEMAWLAEKEKLCTTALNSGDISAVPQTTLLYKNVEMEMQTHWARSK 711
Query: 1623 DLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDV 1444
+I G+ L+ NG I++R Q+ R + + L + Q+ +
Sbjct: 712 GMIAGGERLVQNG-QSKEDIQRRLTQMNHRWERLRVAVDALGNWLSEARHAQQYFQDANE 770
Query: 1443 VESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSE 1264
ESWI EK V+S+D GRD + + LL + + + A++ + I R+ E++ QL +S
Sbjct: 771 AESWIREKMPLVKSDDLGRDEGAAESLLQRHARLEEEIRAYKSD-ISRLEEMQSQLANSA 829
Query: 1263 -HQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAF--AKKASTFN 1093
H + + + T + Q ++++ +E+ + A K
Sbjct: 830 FHTATTSQSVQETEEVNVPQVEMSYNYEGNGMRVSKGEVLALLEKSTPEWWRALKRDGTE 889
Query: 1092 SWF----------ENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLD 943
+ E T +LE + Q +S+ + ++L D+
Sbjct: 890 GYVPANYCKIVPGETVTVTQTTQKTTTTLEGNETKSSVVADRQHKISNDYRELKRLADVR 949
Query: 942 RRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLA 763
RR+ S N+ F + E +R KE E LA E E RR+F KL
Sbjct: 950 RRLLSDNI---KLLRFYRECDE-----FERWAKEIEVSLADE-PSPEHVAAFRRKFDKL- 999
Query: 762 NAFHAWLTNTRQEMMEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERNLILDN 583
+M GGT + ++ + I GQ R+IE +
Sbjct: 1000 ----------EADMKTNGGTQLKHINDIANDL--ISEGHGQSRKIEVR------------ 1035
Query: 582 RYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMMFKHFDKEKT 403
+H I WD L++L + LE + + E A F+ D+
Sbjct: 1036 ---QHK---INAMWDNLERLRKQRGVRLEATERVADFDTTCESAREWMLSKFEQLDRNPN 1089
Query: 402 GRLDHQQFKSCLRAL 358
Q + L+ L
Sbjct: 1090 DVKSLQNLERDLKPL 1104
>gi|50748191|ref|XP_421149.1| PREDICTED: similar to Spectrin beta
chain, brain 4 (Spectrin, non-erythroid beta chain 4)
(Beta-V spectrin) (BSPECV) [Gallus gallus]
Length = 3996
Score = 652 bits (1681), Expect = 0.0
Identities = 403/1385 (29%), Positives = 709/1385 (51%), Gaps = 85/1385 (6%)
Frame = -1
Query: 7218 IRILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQ 7039
++I D I QR++++ K+ S+++R++L+ A F ++ E WI E++Q
Sbjct: 2601 VQIQHKLDTILQRKKQI-------KNLSRSRREKLQTALLLALFYQNLAEAEDWISERMQ 2653
Query: 7038 TAQEENFRDPSNLQAK---IQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKK 6868
++ + +DPSNLQ K +QKH+ FEAE+ A+ + I +++K G A++ H S I++
Sbjct: 2654 KLEDPSIQDPSNLQDKMKLLQKHQVFEAEILANEEIITDVNKKGEALVSMGHPKSGEIRR 2713
Query: 6867 RLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLE 6688
++ L W +G L+ + L F+++ D++ WIREKE + D+G D E
Sbjct: 2714 QVRMLQERWEKLKRAVAARGKMLEDSRDFLEFLQKVDQVEAWIREKEVMINIGDVGNDYE 2773
Query: 6687 HVEILQRKFDDF-------------------------------------------LKELG 6637
H L RK ++F + E
Sbjct: 2774 HCLQLIRKLNEFRGATSGLPGEETEVSEEAICGCLLVYLVYFVAVRNTEVHMEIDILETT 2833
Query: 6636 NHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQR 6457
I IN A KL + E IY++R +N+ W+ + + L GA ++
Sbjct: 2834 VDDAHIKAINALAMKLERQNKEETKTIYQRRKQLNEKWNSFHGNLNAYRRKLEGALEIHA 2893
Query: 6456 FNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAH 6277
R+ D+ I EK + + + DYG+D+ +V+ L R+HE ER++ ++ K+ LE E+
Sbjct: 2894 LIREIDDITERITEKSVLIQALDYGKDVESVENLIRRHEEMEREINVIKSKIEPLELESF 2953
Query: 6276 KLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGD 6097
+L+ +P + + K + K W L+ +A+ RK+ L S+QL +F ++ +++ WI +
Sbjct: 2954 RLSTRNPSINDKLTMKQQEMKNNWLRLQGQAKQRKEKLAASYQLQKFNSEMKEITDWIQN 3013
Query: 6096 MKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQ 5917
++ ++ A L K + AE+++E HQ+ K EI+AR + FN ++ GQ+L G +PE+
Sbjct: 3014 IRGLMEAGGLPKSLNEAESMIEEHQQRKEEIEARVERFNSLSNYGQQLANSGHYATPEIH 3073
Query: 5916 EKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSL 5737
+ L +L + L+ W+E+ I Q DLQ FY EQ E+W++ +EAFLAN DLGDS+
Sbjct: 3074 QSLSRLQKAWTELIQAWQEQYIKLFQAQDLQKFYGYVEQTESWLSSKEAFLANEDLGDSV 3133
Query: 5736 DSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXX 5557
SVE L +KH FEKSL AQ EKI+ + FA +LIQ +HY +D++
Sbjct: 3134 SSVESLQRKHMQFEKSLEAQMEKIDEMASFAQQLIQNKHYDSDNITNRCQAVLRRKEKLL 3193
Query: 5556 XXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQ 5377
R + L+ES Q ++ E+ +WI EK S A+DDS+ DP+N++ KLQKH +F+
Sbjct: 3194 ENAAARRHLLEESRLLQKLLKNSYEVATWINEKNSIAQDDSWRDPSNLQTKLQKHQSFQA 3253
Query: 5376 ELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGN 5197
E+ AN+NRLD I+S GE++I H+A + I RL+++ LW EL+ + K AKL++A
Sbjct: 3254 EIMANKNRLDSIKSEGEKMIRERHYAPEAIQSRLQEMEELWEELLASCQDKRAKLQDAYK 3313
Query: 5196 EQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQ 5017
F R+IED E WL ++E ++ + DLV + + KK +E D +H DR+ +
Sbjct: 3314 ALHFQRSIEDTEKWLEDVENELKAPYSSDDLVVLNSHLKKQEELEQDIASHRDRLQELVN 3373
Query: 5016 LAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAW 4837
AQ+FQ+E+HF A + + + L QRY +LRDPL++R+ L S + FRD+++ELAW
Sbjct: 3374 TAQEFQQEKHFLADELEERVDQLVQRYKSLRDPLQERRGSLEASRLQYEFFRDVDEELAW 3433
Query: 4836 IREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAP 4657
+ EK +A S + G+ L VQ+L +K Q L EI++ D+ ++V S +++ GH +
Sbjct: 3434 VHEKLPMASSRDYGQSLATVQSLQEKHQNLENEISSRDALTKAVLSTGQKLVRGGHSASR 3493
Query: 4656 EIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYG 4477
+I +++ +L + LK++A RR L S +AHQ+L++ + + W++E+ I+ ++DYG
Sbjct: 3494 KIMEQMKELETSVENLKAEAHVRRQRLMQSYEAHQFLTELLDVETWLAERSFILETSDYG 3553
Query: 4476 KDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQP-----MGQLGRDCVLAL 4312
K+E+S +ALL+K A D+E F+ IE +++ + ++ P + +L R L
Sbjct: 3554 KNEESTQALLRKLEATKLDMEGFRPRIEKVQETGASLINKDNPESPAILSKLQR----IL 3609
Query: 4311 YDYQEKSPR-EVSMKKGDVLTLLNASNRDWWKVE--VNDRQGFVPA-------------- 4183
DYQ + E K+ L R++ V+ ++ +Q +
Sbjct: 3610 ADYQSLLQKAETQRKRLQEQFQLYQFEREFQLVDAWLSSKQSIAESDDYGQDLDGVEVLE 3669
Query: 4182 ----AYVKRIEP-------------GTAQQHAQQQVNSIGGKQSEIEDKYQRLMMLGETR 4054
+V I+P ++ + + I + +I + +++L +TR
Sbjct: 3670 KKFKDFVNEIKPLGHSKVLSLNELASKLEKDGHSKTDIIQKRTKQINEMWEKLCHAIQTR 3729
Query: 4053 KRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKAN 3874
L A + +Q + +++ W++ +EAV + G DL V+ L + + + DL A
Sbjct: 3730 TENLRAAQQVHQYDHDVDEVKGWMQEKEAVVDIDDYGYDLPGVQTLLSQLEGVERDLGAI 3789
Query: 3873 EVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRF 3694
L+ + A L+ + I +++ D++ WR L +L A +VQ +
Sbjct: 3790 MKELERIRGEAWHLSRT-YPQLKENIMERLTDVDECWRNLDKKFLERKARLSQAEQVQLY 3848
Query: 3693 HRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANR 3514
D E W E + SE+ D+ + L ++H+ +R++ K + + +
Sbjct: 3849 FNDCRELMAWANEMHALVISEELANDVLGAELLIKRHDEYKREIEKQWLKYEEIQRAGDD 3908
Query: 3513 LRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASM 3334
L ++ + +I + EL+E ++ N RKE ++++ Q + W+A+
Sbjct: 3909 LTRNGHFMSVEIEEKLLELSELMKKVKESWNVRKELYEENWEIQLLRRELEQAEAWLAAK 3968
Query: 3333 NQLVS 3319
+S
Sbjct: 3969 ESFLS 3973
Score = 515 bits (1327), Expect = e-144
Identities = 372/1424 (26%), Positives = 674/1424 (47%), Gaps = 88/1424 (6%)
Frame = -1
Query: 4605 SKAEKRRTDLDDSLQAHQYLSDANE--ADAWMSEKEPIV--GSTDYGKDEDSAEALLKKH 4438
SK E ++ D AH +S A W + +V S+D G D E L++KH
Sbjct: 2509 SKPEFGKSPCDRLTPAHHKVSKITLILATPWTAMPIQVVYLKSSDLGSSVDEVEQLIRKH 2568
Query: 4437 RALLSDLEAFKGTIEDLRKQAS---------------------QCKYQEQPMGQLGRD-- 4327
A L + I L++QA+ Q K Q + + + R+
Sbjct: 2569 EAFEKLLASQDEKITSLQEQANKLEKDGGLDGVQIQHKLDTILQRKKQIKNLSRSRREKL 2628
Query: 4326 ---CVLALYDYQEKSPRE----VSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKR 4168
+LAL+ YQ + E M+K + ++ + SN K+++ + A +
Sbjct: 2629 QTALLLALF-YQNLAEAEDWISERMQKLEDPSIQDPSNLQD-KMKLLQKHQVFEAEILAN 2686
Query: 4167 IEPGTAQQHAQQQVNSIGGKQSE--------IEDKYQRLMMLGETRKRKLEEACKGYQLL 4012
E T + + S+G +S +++++++L R + LE++ + L
Sbjct: 2687 EEIITDVNKKGEALVSMGHPKSGEIRRQVRMLQERWEKLKRAVAARGKMLEDSRDFLEFL 2746
Query: 4011 REANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKG------------------- 3889
++ + + WI+ +E + ++G D E L +K ++F+G
Sbjct: 2747 QKVDQVEAWIREKEVMINIGDVGNDYEHCLQLIRKLNEFRGATSGLPGEETEVSEEAICG 2806
Query: 3888 ------------------------DLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIE 3781
+ ++ ++ +N +A L + ET I Q+ +
Sbjct: 2807 CLLVYLVYFVAVRNTEVHMEIDILETTVDDAHIKAINALAMKLERQNKEETKT-IYQRRK 2865
Query: 3780 DLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQ 3601
LN +W + +L A E+ R++D+ + I EK + + D+G+D+ SV+
Sbjct: 2866 QLNEKWNSFHGNLNAYRRKLEGALEIHALIREIDDITERITEKSVLIQALDYGKDVESVE 2925
Query: 3600 ALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKAN 3421
L R+HE +ER++ + KI+ L+ ++ RL +P +++ Q+E+ W RL +A
Sbjct: 2926 NLIRRHEEMEREINVIKSKIEPLELESFRLSTRNPSINDKLTMKQQEMKNNWLRLQGQAK 2985
Query: 3420 NRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEID 3241
RKEKL SY Q+F S+ +++ WI ++ L+ + L + AE+++E HQ+ + EI+
Sbjct: 2986 QRKEKLAASYQLQKFNSEMKEITDWIQNIRGLMEAGGLPKSLNEAESMIEEHQQRKEEIE 3045
Query: 3240 SRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQL 3061
+R F + +G QL NS HYA +I L + +A L AW + L Q +LQ
Sbjct: 3046 ARVERFNSLSNYGQQLANSGHYATPEIHQSLSRLQKAWTELIQAWQEQYIKLFQAQDLQK 3105
Query: 3060 FYRDCEQADTWMSAREAFLAQED--PSGDNVESLIKKHEDFDKAINTQEEKIKGLKLFAE 2887
FY EQ ++W+S++EAFLA ED S +VESL +KH F+K++ Q EKI + FA+
Sbjct: 3106 FYGYVEQTESWLSSKEAFLANEDLGDSVSSVESLQRKHMQFEKSLEAQMEKIDEMASFAQ 3165
Query: 2886 SLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTE 2707
LI+N HYDS +T + +L R L E +R L ES+ LQ+ +++ E+ W+ E
Sbjct: 3166 QLIQNKHYDSDNITNRCQAVLRRKEKLLENAAARRHLLEESRLLQKLLKNSYEVATWINE 3225
Query: 2706 KFQIAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAV 2527
K IAQ++++RDP+N+Q K QK Q+F+AE+ AN +R+ +I G +I A+
Sbjct: 3226 KNSIAQDDSWRDPSNLQTKLQKHQSFQAEIMANKNRLDSIKSEGEKMIRERHYA--PEAI 3283
Query: 2526 SARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKD 2347
+RL+ + + W+ L+ + +K +L++A K F +++D E WL +VE L++ D
Sbjct: 3284 QSRLQEMEELWEELLASCQDKRAKLQDAYKALHFQRSIEDTEKWLEDVENELKAPYSSDD 3343
Query: 2346 LASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGV 2167
L + + LKK LE DI +H+DR+ E+ A + F ++ ER + RY +
Sbjct: 3344 LVVLNSHLKKQEELEQDIASHRDRLQELVNTAQEFQQEKHFLADELEERVDQLVQRYKSL 3403
Query: 2166 KKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRI 1987
+ +RR L + ++FFRD+D+E +W+ EK + SS DYG+ L VQ+L+ KH+ +
Sbjct: 3404 RDPLQERRGSLEASRLQYEFFRDVDEELAWVHEKLPMASSRDYGQSLATVQSLQEKHQNL 3463
Query: 1986 DTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRL 1807
+ E++S + V G++L+R A +I ++M++LE S ++ R QRL
Sbjct: 3464 ENEISSRDALTKAVLSTGQKLVRGGHSA---SRKIMEQMKELETSVENLKAEAHVRRQRL 3520
Query: 1806 DESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRV 1627
+S FL ++ + E W+ E+ IL + ++G+N Q LL+K + ++D+E + R+
Sbjct: 3521 MQSYEAHQFLTELLDVETWLAERSFILETSDYGKNEESTQALLRKLEATKLDMEGFRPRI 3580
Query: 1626 ADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCD 1447
+ G +LI+ N +P I + ++ A + AE + +L++ QF +
Sbjct: 3581 EKVQETGASLINKDNPESPAILSKLQRILADYQSLLQKAETQRKRLQEQFQLYQFEREFQ 3640
Query: 1446 VVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSS 1267
+V++W++ K+ S+D+G+DL V++L K + F + H + + EL +L
Sbjct: 3641 LVDAWLSSKQSIAESDDYGQDLDGVEVLEKKFKDFVNEIKPLGHSKVLSLNELASKLEKD 3700
Query: 1266 EHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSW 1087
H ++ I+KR + + W+ L + R + + W
Sbjct: 3701 GHSKTDIIQKRTKQINEMWEKLCHAIQTRTENLRAA--------QQVHQYDHDVDEVKGW 3752
Query: 1086 FENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNP 907
+ E + L ++ L +R L + ++ +++ +
Sbjct: 3753 MQEKEAVVDIDDYGYDLPGVQTLLSQLEGVERDLGAIMKELERIRGEAWHLSRTYPQLKE 3812
Query: 906 YTWFTMDALEDTWRNLQRIIKEREQELAREHQRQ-EENDKLRREFAKLANAFHAWLTNTR 730
+ +++ WRNL + ER+ L++ Q Q ND RE AN HA + +
Sbjct: 3813 NIMERLTDVDECWRNLDKKFLERKARLSQAEQVQLYFND--CRELMAWANEMHALVIS-- 3868
Query: 729 QEMMEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERN 598
+E+ E + + +EI+ + +I+ G L RN
Sbjct: 3869 EELANDVLGAELLIKRHDEYKREIEKQWLKYEEIQRAGDDLTRN 3912
Score = 493 bits (1269), Expect = e-137
Identities = 344/1417 (24%), Positives = 663/1417 (46%), Gaps = 82/1417 (5%)
Frame = -1
Query: 6990 IQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXK 6811
I+KHEAFE + + + I +L + N + + I+ +L+ + +
Sbjct: 2565 IRKHEAFEKLLASQDEKITSLQEQANKLEKDGGLDGVQIQHKLDTILQRKKQIKNLSRSR 2624
Query: 6810 GIKLQQALKLLHFIRQCDEILYWIREKETYV---TAEDMGMDLEHVEILQRKFDDFLKEL 6640
KLQ AL L F + E WI E+ + + +D + +++LQ K F E+
Sbjct: 2625 REKLQTALLLALFYQNLAEAEDWISERMQKLEDPSIQDPSNLQDKMKLLQ-KHQVFEAEI 2683
Query: 6639 GNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQ 6460
++ I ++N+ + LV GH + +I ++ + + W +L A R + L +
Sbjct: 2684 LANEEIITDVNKKGEALVSMGHPKSGEIRRQVRMLQERWEKLKRAVAARGKMLEDSRDFL 2743
Query: 6459 RFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEA 6280
F + D+ AWI EK++ ++ D G D + L RK + L G+ ++ +EA
Sbjct: 2744 EFLQKVDQVEAWIREKEVMINIGDVGNDYEHCLQLIRKLNEFRGATSGLPGEETEVSEEA 2803
Query: 6279 -------------------------------------------HKLAETHPDRAEAIHQK 6229
KL + + + I+Q+
Sbjct: 2804 ICGCLLVYLVYFVAVRNTEVHMEIDILETTVDDAHIKAINALAMKLERQNKEETKTIYQR 2863
Query: 6228 NDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAG 6049
WN+ + LE + ++H + + D+ I + +I A + KDV
Sbjct: 2864 RKQLNEKWNSFHGNLNAYRRKLEGALEIHALIREIDDITERITEKSVLIQALDYGKDVES 2923
Query: 6048 AEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGL 5869
E L+ H+E + EI+ +L + ++ K +++ + L G
Sbjct: 2924 VENLIRRHEEMEREINVIKSKIEPLELESFRLSTRNPSINDKLTMKQQEMKNNWLRLQGQ 2983
Query: 5868 WEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKS 5689
++R+ LQ F + ++ W+ + L SL+ E +I++H+ ++
Sbjct: 2984 AKQRKEKLAASYQLQKFNSEMKEITDWIQNIRGLMEAGGLPKSLNEAESMIEEHQQRKEE 3043
Query: 5688 LAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKR 5509
+ A+ E+ N+L + +L HYA ++ + + L ++
Sbjct: 3044 IEARVERFNSLSNYGQQLANSGHYATPEIHQSLSRLQKAWTELIQAWQEQYIKLFQAQDL 3103
Query: 5508 QTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGKLQ-KHINFEQELKANENRLDDIRST 5332
Q F ++ SW++ K + ++ D + LQ KH+ FE+ L+A ++D++ S
Sbjct: 3104 QKFYGYVEQTESWLSSKEAFLANEDLGDSVSSVESLQRKHMQFEKSLEAQMEKIDEMASF 3163
Query: 5331 GEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWL 5152
+Q+I + H+ +D+I +R + V +L++ + L E+ Q+ +N +V W+
Sbjct: 3164 AQQLIQNKHYDSDNITNRCQAVLRRKEKLLENAAARRHLLEESRLLQKLLKNSYEVATWI 3223
Query: 5151 SELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPV 4972
+E + +A +D +D ++Q +K +++ A+ +R+D IK ++ E H+
Sbjct: 3224 NE-KNSIAQDDSWRDPSNLQTKLQKHQSFQAEIMANKNRLDSIKSEGEKMIRERHYAPEA 3282
Query: 4971 IVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGR 4792
I + + +++ + L + ++ KL ++++ R IED W+ + E +
Sbjct: 3283 IQSRLQEMEELWEELLASCQDKRAKLQDAYKALHFQRSIEDTEKWLEDVENELKAPYSSD 3342
Query: 4791 DLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRI 4612
DL+ + + +KKQ+ L +IA+H +++ + + A + Q+ HFLA E+ +++ QL ++
Sbjct: 3343 DLVVLNSHLKKQEELEQDIASHRDRLQELVNTAQEFQQEKHFLADELEERVDQLVQRYKS 3402
Query: 4611 LKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRA 4432
L+ ++RR L+ S +++ D +E AW+ EK P+ S DYG+ + ++L +KH+
Sbjct: 3403 LRDPLQERRGSLEASRLQYEFFRDVDEELAWVHEKLPMASSRDYGQSLATVQSLQEKHQN 3462
Query: 4431 LLSDLEA---------------FKGTIEDLRKQASQCKYQEQPMGQLGRDC-VLALYDYQ 4300
L +++ + +G RK Q K E + L + V Q
Sbjct: 3463 LENEISSRDALTKAVLSTGQKLVRGGHSASRKIMEQMKELETSVENLKAEAHVRRQRLMQ 3522
Query: 4299 EKSPREVSMKKGDVLTLLNASN-----RDWWKVEVN-------------DRQGFVPAAYV 4174
+ + DV T L + D+ K E + D +GF P
Sbjct: 3523 SYEAHQFLTELLDVETWLAERSFILETSDYGKNEESTQALLRKLEATKLDMEGFRPRIEK 3582
Query: 4173 KRIEPGTAQQHAQQQVNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDL 3994
+ + + +I K I YQ L+ ET++++L+E + YQ RE +
Sbjct: 3583 VQETGASLINKDNPESPAILSKLQRILADYQSLLQKAETQRKRLQEQFQLYQFEREFQLV 3642
Query: 3993 AEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKA-NEVRLQEMNQIATALTSVGQ 3817
W+ S++++A + G DL+ VEVL+KKF DF ++K ++ +N++A+ L G
Sbjct: 3643 DAWLSSKQSIAESDDYGQDLDGVEVLEKKFKDFVNEIKPLGHSKVLSLNELASKLEKDGH 3702
Query: 3816 TETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALD 3637
++T + I+++ + +N W L L +A +V ++ DVDE + W+QEK+ +D
Sbjct: 3703 SKTDI-IQKRTKQINEMWEKLCHAIQTRTENLRAAQQVHQYDHDVDEVKGWMQEKEAVVD 3761
Query: 3636 SEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQREL 3457
+D+G DL VQ L + EGVERDL A+ +++ + +A L +++P+ E I + ++
Sbjct: 3762 IDDYGYDLPGVQTLLSQLEGVERDLGAIMKELERIRGEAWHLSRTYPQLKENIMERLTDV 3821
Query: 3456 NEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEAL 3277
+E W L K RK +L + Q + +D R+LM W M+ LV S+ELANDV GAE L
Sbjct: 3822 DECWRNLDKKFLERKARLSQAEQVQLYFNDCRELMAWANEMHALVISEELANDVLGAELL 3881
Query: 3276 LERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVAR 3097
++RH EY+ EI+ + ++ + G+ L + H+ + +IE +L ++E K ++++W R
Sbjct: 3882 IKRHDEYKREIEKQWLKYEEIQRAGDDLTRNGHFMSVEIEEKLLELSELMKKVKESWNVR 3941
Query: 3096 RNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPS 2986
+ + ++ E+QL R+ EQA+ W++A+E+FL+ DPS
Sbjct: 3942 KELYEENWEIQLLRRELEQAEAWLAAKESFLS--DPS 3976
Score = 437 bits (1125), Expect = e-120
Identities = 321/1374 (23%), Positives = 635/1374 (45%), Gaps = 82/1374 (5%)
Frame = -1
Query: 7197 DDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENF 7018
++I ++R ++ + +D +++RL+ A + + D DE N W+ E+ +++
Sbjct: 777 ENIQKQRDKLQTLWQQLQDEVANRKNRLQAAALIKQYFADIDEANSWLQERQTLVASKDY 836
Query: 7017 -RDPSNLQAKIQKHEAFEAEVQAHAKTIANL--------DKTGNAMIQHN---------- 6895
+D S+ +A + +H E E+ A++ + L ++ AM++
Sbjct: 837 GKDESSAEALLHRHLRLEKEIAAYSTEMRRLKEQAAIAAEQAPAAMVKTEAPDDLNQKTA 896
Query: 6894 -----------------------HFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALK 6784
HF E+I K +E+ +L+ + L++ ++
Sbjct: 897 KLPFSRTWATSESALPGSSSLDIHFVPENIWKTQDEIDSLYENLQSMAEDRKKALEEMIE 956
Query: 6783 LLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQ 6604
F C+ W+REKE + ++VE++Q+K+ FL EL + ++ EI
Sbjct: 957 YYRFCSSCEAFQSWMREKENIFRT--LQPQADNVEVMQQKYQSFLTELAAGKGQLGEIES 1014
Query: 6603 AADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAW 6424
A K + ++ +I +++ W + +L + L G V+ F D
Sbjct: 1015 LATKFGKNSPGKYTEIQIWLKEIHARWQHMESLKEEKGSELIGVADVRTFLEDCQSIGVL 1074
Query: 6423 IGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAE 6244
+ +K L + + G +++ +RK ER++ +E K+ L A + +T+P ++
Sbjct: 1075 LQDKMGQLRNLEPGNSPAGLESDKRKLSVVEREILVIERKIEYLRSVAKSIKDTNPAESK 1134
Query: 6243 AIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELA 6064
AI + ++ ++ LK + Q ++D L+++ FL D R L+ W ++ + ++E+
Sbjct: 1135 AITVQVENMESLLVNLKLETQRKRDLLQQAQNQQSFLQDSRRLLLWAEGIREKLRSEEMG 1194
Query: 6063 KDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESP--EVQEKLEKLDHE 5890
DVA AE LL HQ+ EI ++ + F Q G+K+++ S +V +E+L E
Sbjct: 1195 VDVASAEHLLREHQDLLKEIRSQKERFLQLEELGRKIIQKQPSNSRTRDVHLSVERLAEE 1254
Query: 5889 KSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKK 5710
L +WE+R + ++LQ F R+ ++ ++ EAFL DLGD +D+V L K+
Sbjct: 1255 NKELENMWEQRWKKLQDGLELQKFNREGDRINAALSSHEAFLRGDDLGDHVDAVRSLQKQ 1314
Query: 5709 HEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNA 5530
H++FE+ L + +I A +E LI+ H+A+ + E R
Sbjct: 1315 HQEFEQLLMVLKRRIEAFNENGADLIESGHFASHAIKERMATLRQRWERLVENNSKRKQR 1374
Query: 5529 LKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRL 5350
L +S + Q F+RD E++ W+ EK A D+SY DPTN+ KL+ H E+E+ ANE
Sbjct: 1375 LLDSLQLQEFNRDAAELLIWMEEKYKIASDESYRDPTNVLRKLKWHEAAEKEMMANEKHF 1434
Query: 5349 DDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIE 5170
+ G Q+I H+AA I ++ ++ W EL ++G KLR+AG ++Q ++
Sbjct: 1435 ITLIKKGNQLIQDDHYAAASIQKKMSELEKKWKELYGKMIERGDKLRQAGQQEQLMELLQ 1494
Query: 5169 DVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEE 4990
D + + ++E + + G DL S ++L K+ +E++ + ++++ I A +
Sbjct: 1495 DAKKKIEKIEKVLQEAETGHDLRSSRDLLKQHRQLENETHELAEKMNSIVSHAMKMATN- 1553
Query: 4989 HFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAG 4810
HF++ I+ + + +R+ +L+ PL++R++ L + + + + EL WI E+ +A
Sbjct: 1554 HFDSQRILDETQKYLKRFESLQAPLDERRKLLEAAVDLYEFYHYHDMELNWINERLPIAS 1613
Query: 4809 STNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQL 4630
STN G+ L Q+L++K + AE+ H Q++ V MI H A +I +K +L
Sbjct: 1614 STNCGKSLDVAQSLLQKHKEFQAEVNAHKQQVQRVLDKGRTMIVNQHPSAQKINEKCQEL 1673
Query: 4629 RDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEAL 4450
W+ L+ E+R L S+ ++L + ++ +AW++EK P+V S DYGKDED L
Sbjct: 1674 VTAWQGLEKACEERTKQLQHSVGFQEFLMNTSDLEAWIAEKRPLVMSKDYGKDEDGTLKL 1733
Query: 4449 LKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQPMGQLGRDCVLALYDYQEKSPREVSM- 4273
L+KH+ L ++ + +DL K+ ++ MG + V A + RE+
Sbjct: 1734 LQKHKVLEHEIAVY----QDLIKELNESVQNLPAMGSIQYVEVDAPREQVHSRLRELQEL 1789
Query: 4272 -----KKGDVLTLLNASNRDWWKVE---VNDRQGFVPAAYVKRIE--------------- 4162
KK D +L+ R++ ++ +Q Y E
Sbjct: 1790 AATRGKKLDETLVLHEFLREYEDLQDWMAQQKQAASSEDYGNNYEHVLQLRAKYDTFRHQ 1849
Query: 4161 -------PGTAQQHAQQQVNS-------IGGKQSEIEDKYQRLMMLGETRKRKLEEACKG 4024
T QQ A+ +N+ I KQ ++ + ++ L+ + R +L++A
Sbjct: 1850 LEATGKRVMTCQQLAENLLNAGHSESREIRQKQKDLRNSWEELLEITRLRGERLKDAEVI 1909
Query: 4023 YQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQI 3844
++ ++ D I+ + + + ++ D+ V+ + + +L NE +LQ++
Sbjct: 1910 HKCYQDLTDALAHIEEK-SKSIPDDVAKDMRGVQTQLRNHVALEHELLGNEQQLQDLIHS 1968
Query: 3843 ATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDW 3664
A + + E A ++ + + + W+AL L AH++ +F V + W
Sbjct: 1969 ADHVLTRCSNEQASGLKAKQQAIVTNWKALKSKVQLRKELLEQAHKLYQFQAQVWDYFSW 2028
Query: 3663 IQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAE 3484
E + +++ RD+ + +H+ + ++ A +K + + L Q ++
Sbjct: 2029 TSEMIREMRAKETIRDISTSSLRLTQHQQLLAEIEAQEEKYNQIVQLGQSLLQDEEIRSK 2088
Query: 3483 QIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLV 3322
+I + L E+ +++ S+ +K+ L + Q F D+ L + + S +++
Sbjct: 2089 EIRQKLQALLEEKDKVYSEWQQKKKWLDRIHQEQMFYKDWNHLDKLLNSQEEML 2142
Score = 427 bits (1097), Expect = e-117
Identities = 337/1461 (23%), Positives = 649/1461 (44%), Gaps = 83/1461 (5%)
Frame = -1
Query: 7137 SQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENF-RDPSNLQAKIQKHEAFEAE 6961
S+T++ +LEEA + F RD E WI EK + A+ +D S + A IQKH+A EAE
Sbjct: 691 SRTRKSQLEEALKLFEFFRDCKEEEAWISEKWKIARTTTLGKDVSQITASIQKHKALEAE 750
Query: 6960 VQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKL 6781
+H A++ + G + Q N E+I+K+ ++L LW + +LQ A +
Sbjct: 751 CNSHRAICADVMRRGWDLSQKNPTHEENIQKQRDKLQTLWQQLQDEVANRKNRLQAAALI 810
Query: 6780 LHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQA 6601
+ DE W++E++T V ++D G D E L + KE+ + + + +
Sbjct: 811 KQYFADIDEANSWLQERQTLVASKDYGKDESSAEALLHRHLRLEKEIAAYSTEMRRLKEQ 870
Query: 6600 ADKLVEEG-----------------------------------------HSEHDQIYKKR 6544
A E+ H + I+K +
Sbjct: 871 AAIAAEQAPAAMVKTEAPDDLNQKTAKLPFSRTWATSESALPGSSSLDIHFVPENIWKTQ 930
Query: 6543 DDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNV 6364
D+++ + L ++A RK+ L + RF + +W+ EK+ + D NV
Sbjct: 931 DEIDSLYENLQSMAEDRKKALEEMIEYYRFCSSCEAFQSWMREKENIFRTLQPQAD--NV 988
Query: 6363 QALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKA 6184
+ +Q+K++ +LAA +G++ ++E A K + P + I + A W ++
Sbjct: 989 EVMQQKYQSFLTELAAGKGQLGEIESLATKFGKNSPGKYTEIQIWLKEIHARWQHMESLK 1048
Query: 6183 QHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEI 6004
+ + L + FL D + + + D + E AG E+ + EI
Sbjct: 1049 EEKGSELIGVADVRTFLEDCQSIGVLLQDKMGQLRNLEPGNSPAGLESDKRKLSVVEREI 1108
Query: 6003 DARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQ 5824
S + + + ES + ++E ++ +L + +R L +Q + Q
Sbjct: 1109 LVIERKIEYLRSVAKSIKDTNPAESKAITVQVENMESLLVNLKLETQRKRDLLQQAQNQQ 1168
Query: 5823 LFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFA 5644
F +D+ + W L + ++G + S EHL+++H+D K + +Q+E+ L+E
Sbjct: 1169 SFLQDSRRLLLWAEGIREKLRSEEMGVDVASAEHLLREHQDLLKEIRSQKERFLQLEELG 1228
Query: 5643 TKLIQGQ--HYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSW 5470
K+IQ Q + DV R L++ + Q F+R+ D + +
Sbjct: 1229 RKIIQKQPSNSRTRDVHLSVERLAEENKELENMWEQRWKKLQDGLELQKFNREGDRINAA 1288
Query: 5469 ITEKLSTARDDSYLDPTNIRGKLQK-HINFEQELKANENRLDDIRSTGEQIIDSGHFAAD 5293
++ + R D D + LQK H FEQ L + R++ G +I+SGHFA+
Sbjct: 1289 LSSHEAFLRGDDLGDHVDAVRSLQKQHQEFEQLLMVLKRRIEAFNENGADLIESGHFASH 1348
Query: 5292 HIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYG 5113
I +R+ + W LV+ +K+ +L ++ Q+FNR+ ++ W+ E + ++AS++
Sbjct: 1349 AIKERMATLRQRWERLVENNSKRKQRLLDSLQLQEFNRDAAELLIWMEE-KYKIASDESY 1407
Query: 5112 KDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYN 4933
+D +V K E + A+ + + Q +++H+ A I +K L++++
Sbjct: 1408 RDPTNVLRKLKWHEAAEKEMMANEKHFITLIKKGNQLIQDDHYAAASIQKKMSELEKKWK 1467
Query: 4932 ALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQ 4753
L + +R KL ++ Q QL ++D I + E+V G DL ++L+K+ +
Sbjct: 1468 ELYGKMIERGDKLRQAGQQEQLMELLQDAKKKIEKIEKVLQEAETGHDLRSSRDLLKQHR 1527
Query: 4752 ALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLD 4573
L E ++ S+ S A M HF + I D+ + + L++ ++RR L+
Sbjct: 1528 QLENETHELAEKMNSIVSHAMKMATN-HFDSQRILDETQKYLKRFESLQAPLDERRKLLE 1586
Query: 4572 DSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIE 4393
++ +++ + W++E+ PI ST+ GK D A++LL+KH+ +++ A K ++
Sbjct: 1587 AAVDLYEFYHYHDMELNWINERLPIASSTNCGKSLDVAQSLLQKHKEFQAEVNAHKQQVQ 1646
Query: 4392 DLRKQASQCKYQEQPMGQ-LGRDCVLALYDYQ------EKSPREVSMKKGDVLTLLNASN 4234
+ + + P Q + C + +Q E+ +++ G L+N S+
Sbjct: 1647 RVLDKGRTMIVNQHPSAQKINEKCQELVTAWQGLEKACEERTKQLQHSVGFQEFLMNTSD 1706
Query: 4233 RDWWKVEVNDRQGFVPAAYVKRIEPGTA---QQH-------------------AQQQVNS 4120
+ W + +++ V + + E GT Q+H + Q + +
Sbjct: 1707 LEAW---IAEKRPLVMSKDYGKDEDGTLKLLQKHKVLEHEIAVYQDLIKELNESVQNLPA 1763
Query: 4119 IGGKQ--------SEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAV 3964
+G Q ++ + + L L TR +KL+E ++ LRE DL +W+ ++
Sbjct: 1764 MGSIQYVEVDAPREQVHSRLRELQELAATRGKKLDETLVLHEFLREYEDLQDWMAQQKQA 1823
Query: 3963 AAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQI 3784
A+ ++ G + E V L+ K+D F+ L+A R+ Q+A L + G +E+ IRQ+
Sbjct: 1824 ASSEDYGNNYEHVLQLRAKYDTFRHQLEATGKRVMTCQQLAENLLNAGHSESR-EIRQKQ 1882
Query: 3783 EDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSV 3604
+DL W L +L A + + ++D+ + I+EK ++ +D +D+R V
Sbjct: 1883 KDLRNSWEELLEITRLRGERLKDAEVIHKCYQDLTDALAHIEEKSKSIP-DDVAKDMRGV 1941
Query: 3603 QALQRKHEGVERDLAALGDKIKSLDEKANR-LRQSHPEAAEQIYDLQRELNEQWNRLTSK 3427
Q R H +E +L +++ L A+ L + E A + Q+ + W L SK
Sbjct: 1942 QTQLRNHVALEHELLGNEQQLQDLIHSADHVLTRCSNEQASGLKAKQQAIVTNWKALKSK 2001
Query: 3426 ANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTE 3247
RKE L ++ +F + D W + M + + ++E D++ + L +HQ+ E
Sbjct: 2002 VQLRKELLEQAHKLYQFQAQVWDYFSWTSEMIREMRAKETIRDISTSSLRLTQHQQLLAE 2061
Query: 3246 IDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLEL 3067
I+++ + Q G LL + +I +LQ + E + + W ++ LD+ +
Sbjct: 2062 IEAQEEKYNQIVQLGQSLLQDEEIRSKEIRQKLQALLEEKDKVYSEWQQKKKWLDRIHQE 2121
Query: 3066 QLFYRDCEQADTWMSAREAFL 3004
Q+FY+D D ++++E L
Sbjct: 2122 QMFYKDWNHLDKLLNSQEEML 2142
Score = 417 bits (1071), Expect = e-114
Identities = 369/1657 (22%), Positives = 725/1657 (43%), Gaps = 98/1657 (5%)
Frame = -1
Query: 5910 LEKLDHEKSSLLGLWEERRILYEQCMDL-QLFYRDTEQAETWMNKQEAFLANTDLG-DSL 5737
LEK +H + L ++ + E+ L + F + ET++ + D +S+
Sbjct: 466 LEKAEHNRGKAL---QKEMLRLEKLEQLAKRFLKKAALRETYLEDMRKVIGKQDFWPESV 522
Query: 5736 DSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXX 5557
D +E KK E + + E+ +L E AT + Q +++ D + +
Sbjct: 523 DRMEAASKKLEAIVADVLPRRERFASLAEMATVISQNNYHSKDQIVKKENSISKQWQDLL 582
Query: 5556 XXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARD-DSYLDPTNIRGKLQKHINFE 5380
R ++L + RD D ++ + E + D + LQKH +
Sbjct: 583 DQLQKRQHSLSTMQEILALLRDIDAIMEELKELQALVNSQDCGKQLLEVVDLLQKHNLID 642
Query: 5379 QELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAG 5200
++ + +++L I +I A+ + ++ + L+ L+ + + ++L EA
Sbjct: 643 LQISSYDDKLTHITQRTAEISKDSTVKAEVLYAKVPMLRQLYQNLIAQSRTRKSQLEEAL 702
Query: 5199 NEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIK 5020
+F R+ ++ EAW+SE + GKD+ + +K +E++ N+H +
Sbjct: 703 KLFEFFRDCKEEEAWISEKWKIARTTTLGKDVSQITASIQKHKALEAECNSHRAICADVM 762
Query: 5019 QLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELA 4840
+ ++ + I ++++ LQ + L+D + RK +L + Q F DI++ +
Sbjct: 763 RRGWDLSQKNPTHEENIQKQRDKLQTLWQQLQDEVANRKNRLQAAALIKQYFADIDEANS 822
Query: 4839 WIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQG---- 4672
W++E++ + S + G+D + L+ + L EIA + +++ + A +Q
Sbjct: 823 WLQERQTLVASKDYGKDESSAEALLHRHLRLEKEIAAYSTEMRRLKEQAAIAAEQAPAAM 882
Query: 4671 -------------------------------------HFLAPEI---RDKLAQLRDNWRI 4612
HF+ I +D++ L +N
Sbjct: 883 VKTEAPDDLNQKTAKLPFSRTWATSESALPGSSSLDIHFVPENIWKTQDEIDSLYEN--- 939
Query: 4611 LKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRA 4432
L+S AE R+ L++ ++ +++ S +WM EKE I + D+ E + +K+++
Sbjct: 940 LQSMAEDRKKALEEMIEYYRFCSSCEAFQSWMREKENIFRTLQ--PQADNVEVMQQKYQS 997
Query: 4431 LLSDLEAFKGTIEDLRKQASQC------KYQEQPMGQLGRDCVLALYDYQEKSPREVSMK 4270
L++L A KG + ++ A++ KY E Q+ + A + + E E +
Sbjct: 998 FLTELAAGKGQLGEIESLATKFGKNSPGKYTEI---QIWLKEIHARWQHMESLKEEKGSE 1054
Query: 4269 K---GDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIEPGTAQQHAQQQVNSIGGKQSE 4099
DV T L V + D+ G ++ +EPG + + + + E
Sbjct: 1055 LIGVADVRTFLEDCQSIG--VLLQDKMG-----QLRNLEPGNSPAGLESDKRKLSVVERE 1107
Query: 4098 I---EDKYQRLMMLGET-------------------------------RKRKLEEACKGY 4021
I E K + L + ++ RKR L + +
Sbjct: 1108 ILVIERKIEYLRSVAKSIKDTNPAESKAITVQVENMESLLVNLKLETQRKRDLLQQAQNQ 1167
Query: 4020 Q-LLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQI 3844
Q L+++ L W + +E+G D+ E L ++ D ++++ + R ++ ++
Sbjct: 1168 QSFLQDSRRLLLWAEGIREKLRSEEMGVDVASAEHLLREHQDLLKEIRSQKERFLQLEEL 1227
Query: 3843 ATALTSVGQTETAVR-IRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRD 3667
+ + + R + +E L + L +L E+Q+F+R+ D
Sbjct: 1228 GRKIIQKQPSNSRTRDVHLSVERLAEENKELENMWEQRWKKLQDGLELQKFNREGDRINA 1287
Query: 3666 WIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAA 3487
+ + L +D G + +V++LQ++H+ E+ L L +I++ +E L +S A+
Sbjct: 1288 ALSSHEAFLRGDDLGDHVDAVRSLQKQHQEFEQLLMVLKRRIEAFNENGADLIESGHFAS 1347
Query: 3486 EQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQEL 3307
I + L ++W RL + RK++LLDS Q F D +L+ W+ + ++S E
Sbjct: 1348 HAIKERMATLRQRWERLVENNSKRKQRLLDSLQLQEFNRDAAELLIWMEEKYK-IASDES 1406
Query: 3306 ANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEAR 3127
D T L+ H+ E+ + F + GNQL+ HYAA I+ ++ + +
Sbjct: 1407 YRDPTNVLRKLKWHEAAEKEMMANEKHFITLIKKGNQLIQDDHYAAASIQKKMSELEKKW 1466
Query: 3126 KGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGDNVES---LIKK 2956
K L + R + L Q + + + A + E L QE +G ++ S L+K+
Sbjct: 1467 KELYGKMIERGDKLRQAGQQEQLMELLQDAKKKIEKIEKVL-QEAETGHDLRSSRDLLKQ 1525
Query: 2955 HEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFK 2776
H + + EK+ + A + NH+DS + + + L R+ L+ L ++R
Sbjct: 1526 HRQLENETHELAEKMNSIVSHAMKMA-TNHFDSQRILDETQKYLKRFESLQAPLDERRKL 1584
Query: 2775 LGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNIQQKH-QKQQAFEAELHANSDR 2599
L + L +F D NW+ E+ IA N ++ Q QK + F+AE++A+ +
Sbjct: 1585 LEAAVDLYEFYHYHDMELNWINERLPIASSTNCGKSLDVAQSLLQKHKEFQAEVNAHKQQ 1644
Query: 2598 IAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMA 2419
+ ++ G +I N + ++ + + L W L K E++ +L+ + + F+
Sbjct: 1645 VQRVLDKGRTMIVNQHPSAQK--INEKCQELVTAWQGLEKACEERTKQLQHSVGFQEFLM 1702
Query: 2418 AVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLL 2239
DLE W+ E L+ S+DYGKD LL+KH +LE +I +QD + E+NE +L
Sbjct: 1703 NTSDLEAWIAEKRPLVMSKDYGKDEDGTLKLLQKHKVLEHEIAVYQDLIKELNESVQNLP 1762
Query: 2238 ENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKL 2059
Q ++ R+ + R ++++A R KL + L +H+F R+ +D + W+ ++K
Sbjct: 1763 AMGSIQYVEVDAPREQVHSRLRELQELAATRGKKLDETLVLHEFLREYEDLQDWMAQQKQ 1822
Query: 2058 LVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGED-QI 1882
SS+DYG + V LR K+ +L + +V + E LL AG E +I
Sbjct: 1823 AASSEDYGNNYEHVLQLRAKYDTFRHQLEATGKRVMTCQQLAENLL----NAGHSESREI 1878
Query: 1881 KKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGEN 1702
+++ +DL SW ++ ++T R +RL ++E D+ + A + EK + + D+ ++
Sbjct: 1879 RQKQKDLRNSWEELLEITRLRGERLKDAEVIHKCYQDLTDALAHIEEKSKSI-PDDVAKD 1937
Query: 1701 MAGVQGLLKKHDTFQVDLELHKQRVADLINKGD-TLIHNGNHHAPHIKQRCDQLRARLIE 1525
M GVQ L+ H + +L ++Q++ DLI+ D L N A +K + +
Sbjct: 1938 MRGVQTQLRNHVALEHELLGNEQQLQDLIHSADHVLTRCSNEQASGLKAKQQAIVTNWKA 1997
Query: 1524 IESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEA 1345
++S + R L QF + SW +E +++R+++ RD+S+ + LT+ +
Sbjct: 1998 LKSKVQLRKELLEQAHKLYQFQAQVWDYFSWTSEMIREMRAKETIRDISTSSLRLTQHQQ 2057
Query: 1344 FDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKR 1234
A + A + E +I +L L+ E +S I ++
Sbjct: 2058 LLAEIEA-QEEKYNQIVQLGQSLLQDEEIRSKEIRQK 2093
Score = 397 bits (1019), Expect = e-108
Identities = 318/1453 (21%), Positives = 646/1453 (43%), Gaps = 91/1453 (6%)
Frame = -1
Query: 5793 TWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYA 5614
T M Q +L ++DLG S+D VE LI+KHE FEK LA+Q+EKI +L E A KL +
Sbjct: 2540 TAMPIQVVYLKSSDLGSSVDEVEQLIRKHEAFEKLLASQDEKITSLQEQANKLEKDGGLD 2599
Query: 5613 ADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDS 5434
+ R L+ + F ++ E WI+E++ D S
Sbjct: 2600 GVQIQHKLDTILQRKKQIKNLSRSRREKLQTALLLALFYQNLAEAEDWISERMQKLEDPS 2659
Query: 5433 YLDPTNIRGK---LQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVN 5263
DP+N++ K LQKH FE E+ ANE + D+ GE ++ GH + I ++R +
Sbjct: 2660 IQDPSNLQDKMKLLQKHQVFEAEILANEEIITDVNKKGEALVSMGHPKSGEIRRQVRMLQ 2719
Query: 5262 NLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKD-------- 5107
W +L A +G L ++ + +F + ++ VEAW+ E E + D G D
Sbjct: 2720 ERWEKLKRAVAARGKMLEDSRDFLEFLQKVDQVEAWIREKEVMINIGDVGNDYEHCLQLI 2779
Query: 5106 -----------------------------------LVSVQNLQKKIGLIESDFNAHNDRV 5032
V+V+N + + + + + +
Sbjct: 2780 RKLNEFRGATSGLPGEETEVSEEAICGCLLVYLVYFVAVRNTEVHMEIDILETTVDDAHI 2839
Query: 5031 DGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIE 4852
I LA + + + I ++++ L +++N+ L +RKL + + + L R+I+
Sbjct: 2840 KAINALAMKLERQNKEETKTIYQRRKQLNEKWNSFHGNLNAYRRKLEGALEIHALIREID 2899
Query: 4851 DELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQG 4672
D I EK + + + G+D+ V+NLI++ + + EI S+IE + + + +
Sbjct: 2900 DITERITEKSVLIQALDYGKDVESVENLIRRHEEMEREINVIKSKIEPLELESFRLSTRN 2959
Query: 4671 HFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVG 4492
+ ++ K ++++NW L+ +A++R+ L S Q ++ S+ E W+ ++
Sbjct: 2960 PSINDKLTMKQQEMKNNWLRLQGQAKQRKEKLAASYQLQKFNSEMKEITDWIQNIRGLME 3019
Query: 4491 STDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQC------------------ 4366
+ K + AE+++++H+ ++EA L Q
Sbjct: 3020 AGGLPKSLNEAESMIEEHQQRKEEIEARVERFNSLSNYGQQLANSGHYATPEIHQSLSRL 3079
Query: 4365 ---------KYQEQPMGQLGRDCVLALYDYQEKSPREVSMKK--------GDVLTLLNAS 4237
+QEQ + + Y Y E++ +S K+ GD ++ + +
Sbjct: 3080 QKAWTELIQAWQEQYIKLFQAQDLQKFYGYVEQTESWLSSKEAFLANEDLGDSVSSVESL 3139
Query: 4236 NRDWWKVEVNDRQGFVPAAYVKRIE--PGTAQQHAQQQ---VNSIGGKQSEIEDKYQRLM 4072
R + E + A +++I+ AQQ Q + ++I + + + ++L+
Sbjct: 3140 QRKHMQFEKS------LEAQMEKIDEMASFAQQLIQNKHYDSDNITNRCQAVLRRKEKLL 3193
Query: 4071 MLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFK 3892
R+ LEE+ +LL+ + ++A WI + ++ AQ + D ++ +K F+
Sbjct: 3194 ENAAARRHLLEESRLLQKLLKNSYEVATWINEKNSI-AQDDSWRDPSNLQTKLQKHQSFQ 3252
Query: 3891 GDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSA 3712
++ AN+ RL + + + I+ +++++ W L +L A
Sbjct: 3253 AEIMANKNRLDSIKSEGEKMIR-ERHYAPEAIQSRLQEMEELWEELLASCQDKRAKLQDA 3311
Query: 3711 HEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSL 3532
++ F R +++T W+++ ++ L + DL + + +K E +E+D+A+ D+++ L
Sbjct: 3312 YKALHFQRSIEDTEKWLEDVENELKAPYSSDDLVVLNSHLKKQEELEQDIASHRDRLQEL 3371
Query: 3531 DEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLM 3352
A +Q A+++ + +L +++ L R+ L S F D + +
Sbjct: 3372 VNTAQEFQQEKHFLADELEERVDQLVQRYKSLRDPLQERRGSLEASRLQYEFFRDVDEEL 3431
Query: 3351 QWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYA 3172
W+ + SS++ + ++L E+HQ EI SR A +A G +L+ H A
Sbjct: 3432 AWVHEKLPMASSRDYGQSLATVQSLQEKHQNLENEISSRDALTKAVLSTGQKLVRGGHSA 3491
Query: 3171 AGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQED 2992
+ I +++ + + + L+ RR L Q E F + +TW++ R +F+ +
Sbjct: 3492 SRKIMEQMKELETSVENLKAEAHVRRQRLMQSYEAHQFLTELLDVETWLAER-SFILETS 3550
Query: 2991 PSGDNVES---LIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILD 2821
G N ES L++K E + +I+ ++ SLI ++ +SPA+ K +IL
Sbjct: 3551 DYGKNEESTQALLRKLEATKLDMEGFRPRIEKVQETGASLINKDNPESPAILSKLQRILA 3610
Query: 2820 RWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENY-RDPTNIQQKHQ 2644
+ L + +R +L E L QF R+ ++ W++ K IA+ ++Y +D ++ +
Sbjct: 3611 DYQSLLQKAETQRKRLQEQFQLYQFEREFQLVDAWLSSKQSIAESDDYGQDLDGVEVLEK 3670
Query: 2643 KQQAFEAELH-ANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTE 2467
K + F E+ ++ ++ + + L ++ + R K +N+ W+ L
Sbjct: 3671 KFKDFVNEIKPLGHSKVLSLNELASKLEKDGH--SKTDIIQKRTKQINEMWEKLCHAIQT 3728
Query: 2466 KSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVA 2287
++ L+ A + + V +++ W+ E E ++ +DYG DL V+ LL + +E D+ A
Sbjct: 3729 RTENLRAAQQVHQYDHDVDEVKGWMQEKEAVVDIDDYGYDLPGVQTLLSQLEGVERDLGA 3788
Query: 2286 HQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQF 2107
+ + +A L + I ER + + + + K +R+ +LS+A V +
Sbjct: 3789 IMKELERIRGEAWHLSRTYPQLKENIMERLTDVDECWRNLDKKFLERKARLSQAEQVQLY 3848
Query: 2106 FRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEE 1927
F D + +W E LV S++ D+ G + L ++H E+ + ++ G++
Sbjct: 3849 FNDCRELMAWANEMHALVISEELANDVLGAELLIKRHDEYKREIEKQWLKYEEIQRAGDD 3908
Query: 1926 LLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWM 1747
L R+ V +I++++ +L + ++++ R + +E+ Q ++E+ EAW+
Sbjct: 3909 LTRNGHFMSV---EIEEKLLELSELMKKVKESWNVRKELYEENWEIQLLRRELEQAEAWL 3965
Query: 1746 NEKQQILGSDNFG 1708
K+ L ++G
Sbjct: 3966 AAKESFLSDPSYG 3978
Score = 391 bits (1004), Expect = e-106
Identities = 315/1477 (21%), Positives = 643/1477 (43%), Gaps = 15/1477 (1%)
Frame = -1
Query: 5127 SEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENL 4948
S D G + V+ L +K E + ++++ +++ A + +++ + I K + +
Sbjct: 2551 SSDLGSSVDEVEQLIRKHEAFEKLLASQDEKITSLQEQANKLEKDGGLDGVQIQHKLDTI 2610
Query: 4947 QQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAG--STNRGRDLIGVQ 4774
QR +++ R+ KL + ++++ + WI E+ Q S +L
Sbjct: 2611 LQRKKQIKNLSRSRREKLQTALLLALFYQNLAEAEDWISERMQKLEDPSIQDPSNLQDKM 2670
Query: 4773 NLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAE 4594
L++K Q AEI ++ I V+ ++ GH + EIR ++ L++ W LK
Sbjct: 2671 KLLQKHQVFEAEILANEEIITDVNKKGEALVSMGHPKSGEIRRQVRMLQERWEKLKRAVA 2730
Query: 4593 KRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLE 4414
R L+DS ++L ++ +AW+ EKE ++ D G D + L++K L
Sbjct: 2731 ARGKMLEDSRDFLEFLQKVDQVEAWIREKEVMINIGDVGNDYEHCLQLIRK-------LN 2783
Query: 4413 AFKGTIEDLRKQASQCKYQEQPMGQLGRDCVLALYDYQEKSPREVSMKKGDVLTLLNASN 4234
F+G L + ++ +E G C+L Y V+++ +V
Sbjct: 2784 EFRGATSGLPGEETEVS-EEAICG-----CLLVYLVYF------VAVRNTEV-------- 2823
Query: 4233 RDWWKVEVNDRQGFVPAAYVKRIEPGTAQQHAQ--QQVNSIGGKQSEIEDKYQRLMMLGE 4060
+E++ + V A++K I + Q ++ +I ++ ++ +K+
Sbjct: 2824 ----HMEIDILETTVDDAHIKAINALAMKLERQNKEETKTIYQRRKQLNEKWNSFHGNLN 2879
Query: 4059 TRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLK 3880
+RKLE A + + L+RE +D+ E I + + + G D+E VE L ++ ++ + ++
Sbjct: 2880 AYRRKLEGALEIHALIREIDDITERITEKSVLIQALDYGKDVESVENLIRRHEEMEREIN 2939
Query: 3879 ANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQ 3700
+ +++ + ++ + S ++ + +++ W L +L +++++Q
Sbjct: 2940 VIKSKIEPL-ELESFRLSTRNPSINDKLTMKQQEMKNNWLRLQGQAKQRKEKLAASYQLQ 2998
Query: 3699 RFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKA 3520
+F+ ++ E DWIQ +++ + L +++ +H+ + ++ A ++ SL
Sbjct: 2999 KFNSEMKEITDWIQNIRGLMEAGGLPKSLNEAESMIEEHQQRKEEIEARVERFNSLSNYG 3058
Query: 3519 NRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIA 3340
+L S A +I+ L + W L + KL + D Q+F W++
Sbjct: 3059 QQLANSGHYATPEIHQSLSRLQKAWTELIQAWQEQYIKLFQAQDLQKFYGYVEQTESWLS 3118
Query: 3339 SMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDI 3160
S +++++L + V+ E+L +H ++ ++++ F QL+ + HY + +I
Sbjct: 3119 SKEAFLANEDLGDSVSSVESLQRKHMQFEKSLEAQMEKIDEMASFAQQLIQNKHYDSDNI 3178
Query: 3159 ENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGD 2980
NR Q V ++ L + ARR++L++ LQ ++ + TW++ + + +AQ+D D
Sbjct: 3179 TNRCQAVLRRKEKLLENAAARRHLLEESRLLQKLLKNSYEVATWINEKNS-IAQDDSWRD 3237
Query: 2979 --NVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGL 2806
N+++ ++KH+ F I + ++ +K E +I+ HY A+ + ++ + W L
Sbjct: 3238 PSNLQTKLQKHQSFQAEIMANKNRLDSIKSEGEKMIRERHYAPEAIQSRLQEMEELWEEL 3297
Query: 2805 KEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENYRDPTNIQQKH-QKQQAF 2629
+ KR KL ++ F R ++ E W+ + + D + H +KQ+
Sbjct: 3298 LASCQDKRAKLQDAYKALHFQRSIEDTEKWLEDVENELKAPYSSDDLVVLNSHLKKQEEL 3357
Query: 2628 EAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLK 2449
E ++ ++ DR+ ++ + E + R+ L ++ L E+ L+
Sbjct: 3358 EQDIASHRDRLQELVNTAQEFQQEKHFLADE--LEERVDQLVQRYKSLRDPLQERRGSLE 3415
Query: 2448 EANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVG 2269
+ Q F V + W+ E + S DYG+ LA+V++L +KH LE +I +
Sbjct: 3416 ASRLQYEFFRDVDEELAWVHEKLPMASSRDYGQSLATVQSLQEKHQNLENEISSRDALTK 3475
Query: 2268 EMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDD 2089
+ L+ ++I E+ K + + +K A RR +L ++ HQF ++ D
Sbjct: 3476 AVLSTGQKLVRGGHSASRKIMEQMKELETSVENLKAEAHVRRQRLMQSYEAHQFLTELLD 3535
Query: 2088 EESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAA 1909
E+W+ E+ ++ + DYG++ Q L RK ++ P++ V+ G L+
Sbjct: 3536 VETWLAERSFILETSDYGKNEESTQALLRKLEATKLDMEGFRPRIEKVQETGASLIN--- 3592
Query: 1908 EAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQI 1729
+ I +++ + + + + +RL E F + + +AW++ KQ I
Sbjct: 3593 KDNPESPAILSKLQRILADYQSLLQKAETQRKRLQEQFQLYQFEREFQLVDAWLSSKQSI 3652
Query: 1728 LGSDNFGENMAGVQGLLKKHDTFQVDLE-LHKQRVADLINKGDTLIHNGNHHAPHIKQRC 1552
SD++G+++ GV+ L KK F +++ L +V L L +G+ I++R
Sbjct: 3653 AESDDYGQDLDGVEVLEKKFKDFVNEIKPLGHSKVLSLNELASKLEKDGHSKTDIIQKRT 3712
Query: 1551 DQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSV 1372
Q+ ++ + R LR Q+ D V+ W+ EKE V +D+G DL V
Sbjct: 3713 KQINEMWEKLCHAIQTRTENLRAAQQVHQYDHDVDEVKGWMQEKEAVVDIDDYGYDLPGV 3772
Query: 1371 QILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAH 1192
Q LL++ E + L A E ++RI L + Q I +R T+V + W+NL
Sbjct: 3773 QTLLSQLEGVERDLGAIMKE-LERIRGEAWHLSRTYPQLKENIMERLTDVDECWRNLDKK 3831
Query: 1191 SEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRD 1012
R+ E++ L F +W + N + L
Sbjct: 3832 FLERKARLSQA-------EQVQLYF-NDCRELMAWANEMHALVISEELANDVLGAELLIK 3883
Query: 1011 AHGEFQRSLSSAEEDFRQLQ----DLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIK 844
H E++R + + ++Q DL R +V +E+ L ++K
Sbjct: 3884 RHDEYKREIEKQWLKYEEIQRAGDDLTRNGHFMSV-----------EIEEKLLELSELMK 3932
Query: 843 EREQELAREHQRQEEN---DKLRREFAKLANAFHAWL 742
+ ++ + EEN LRRE + AWL
Sbjct: 3933 KVKESWNVRKELYEENWEIQLLRRELEQA----EAWL 3965
Score = 380 bits (977), Expect = e-103
Identities = 301/1445 (20%), Positives = 612/1445 (41%), Gaps = 90/1445 (6%)
Frame = -1
Query: 6723 YVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKR 6544
Y+ + D+G ++ VE L RK + F K L + +I + + A+KL ++G + QI K
Sbjct: 2548 YLKSSDLGSSVDEVEQLIRKHEAFEKLLASQDEKITSLQEQANKLEKDGGLDGVQIQHKL 2607
Query: 6543 DDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNV 6364
D + ++ L+ +R+E L A + F ++ E WI E+ L D +D +N+
Sbjct: 2608 DTILQRKKQIKNLSRSRREKLQTALLLALFYQNLAEAEDWISERMQKL-EDPSIQDPSNL 2666
Query: 6363 Q---ALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALK 6193
Q L +KH+ E ++ A E + + K+ L ++ I ++ + W LK
Sbjct: 2667 QDKMKLLQKHQVFEAEILANEEIITDVNKKGEALVSMGHPKSGEIRRQVRMLQERWEKLK 2726
Query: 6192 EKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHK 6013
R LE S FL + +WI + + +I ++ D L+ E +
Sbjct: 2727 RAVAARGKMLEDSRDFLEFLQKVDQVEAWIREKEVMINIGDVGNDYEHCLQLIRKLNEFR 2786
Query: 6012 G----------------------------------EIDARADSFNQTA---------SAG 5962
G E+ D T +
Sbjct: 2787 GATSGLPGEETEVSEEAICGCLLVYLVYFVAVRNTEVHMEIDILETTVDDAHIKAINALA 2846
Query: 5961 QKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMN 5782
KL E+ + ++ ++L+ + +S G R E +++ R+ + +
Sbjct: 2847 MKLERQNKEETKTIYQRRKQLNEKWNSFHGNLNAYRRKLEGALEIHALIREIDDITERIT 2906
Query: 5781 KQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDV 5602
++ + D G ++SVE+LI++HE+ E+ + + KI L+ + +L D +
Sbjct: 2907 EKSVLIQALDYGKDVESVENLIRRHEEMEREINVIKSKIEPLELESFRLSTRNPSINDKL 2966
Query: 5601 AEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDP 5422
R L SY+ Q F+ + E+ WI
Sbjct: 2967 TMKQQEMKNNWLRLQGQAKQRKEKLAASYQLQKFNSEMKEITDWIQNIRGLMEAGGLPKS 3026
Query: 5421 TN-IRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNEL 5245
N +++H ++E++A R + + + G+Q+ +SGH+A I L ++ W EL
Sbjct: 3027 LNEAESMIEEHQQRKEEIEARVERFNSLSNYGQQLANSGHYATPEIHQSLSRLQKAWTEL 3086
Query: 5244 VDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLI 5065
+ A ++ KL +A + Q+F +E E+WLS E +A+ED G + SV++LQ+K
Sbjct: 3087 IQAWQEQYIKLFQAQDLQKFYGYVEQTESWLSSKEAFLANEDLGDSVSSVESLQRKHMQF 3146
Query: 5064 ESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGES 4885
E A +++D + AQQ + +H+++ I + + + +R L + R+ L ES
Sbjct: 3147 EKSLEAQMEKIDEMASFAQQLIQNKHYDSDNITNRCQAVLRRKEKLLENAAARRHLLEES 3206
Query: 4884 HQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESV 4705
+L ++ + WI EK +A + RD +Q ++K Q+ AEI + ++++S+
Sbjct: 3207 RLLQKLLKNSYEVATWINEKNSIA-QDDSWRDPSNLQTKLQKHQSFQAEIMANKNRLDSI 3265
Query: 4704 SSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEAD 4525
S MI++ H+ I+ +L ++ + W L + + +R L D+ +A + + +
Sbjct: 3266 KSEGEKMIRERHYAPEAIQSRLQEMEELWEELLASCQDKRAKLQDAYKALHFQRSIEDTE 3325
Query: 4524 AWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQ---- 4357
W+ + E + + D + LKK L D+ + + +++L A + + +
Sbjct: 3326 KWLEDVENELKAPYSSDDLVVLNSHLKKQEELEQDIASHRDRLQELVNTAQEFQQEKHFL 3385
Query: 4356 ----EQPMGQL---------------------------GRDCVLALYDYQEKSPREVSMK 4270
E+ + QL RD L EK P S
Sbjct: 3386 ADELEERVDQLVQRYKSLRDPLQERRGSLEASRLQYEFFRDVDEELAWVHEKLPMASSRD 3445
Query: 4269 KGDVLTLLNASNRDWWKV--EVNDRQGFVPAAYVKRIEPGTAQQHAQQQVNSIGGKQSEI 4096
G L + + + E++ R A + A +++ + E+
Sbjct: 3446 YGQSLATVQSLQEKHQNLENEISSRDALTKAVLSTGQKLVRGGHSASRKIME---QMKEL 3502
Query: 4095 EDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVL 3916
E + L R+++L ++ + +Q L E D+ W+ R + + G + E + L
Sbjct: 3503 ETSVENLKAEAHVRRQRLMQSYEAHQFLTELLDVETWLAERSFILETSDYGKNEESTQAL 3562
Query: 3915 QKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXX 3736
+K + K D++ R++++ + +L + E+ I +++ + A +++L
Sbjct: 3563 LRKLEATKLDMEGFRPRIEKVQETGASLINKDNPESPA-ILSKLQRILADYQSLLQKAET 3621
Query: 3735 XXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAA 3556
+L ++ +F R+ W+ K +S+D+G+DL V+ L++K + ++
Sbjct: 3622 QRKRLQEQFQLYQFEREFQLVDAWLSSKQSIAESDDYGQDLDGVEVLEKKFKDFVNEIKP 3681
Query: 3555 LG-DKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQR 3379
LG K+ SL+E A++L + + I +++NE W +L R E L + +
Sbjct: 3682 LGHSKVLSLNELASKLEKDGHSKTDIIQKRTKQINEMWEKLCHAIQTRTENLRAAQQVHQ 3741
Query: 3378 FLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGN 3199
+ D ++ W+ +V + D+ G + LL + + ++ + +
Sbjct: 3742 YDHDVDEVKGWMQEKEAVVDIDDYGYDLPGVQTLLSQLEGVERDLGAIMKELERIRGEAW 3801
Query: 3198 QLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSA 3019
L ++ +I RL V+E + L+ ++ R+ L Q ++QL++ DC + W +
Sbjct: 3802 HLSRTYPQLKENIMERLTDVDECWRNLDKKFLERKARLSQAEQVQLYFNDCRELMAWANE 3861
Query: 3018 REAFLAQEDPSGD--NVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVT 2845
A + E+ + D E LIK+H+++ + I Q K + ++ + L +N H+ S +
Sbjct: 3862 MHALVISEELANDVLGAELLIKRHDEYKREIEKQWLKYEEIQRAGDDLTRNGHFMSVEIE 3921
Query: 2844 RKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENY---R 2674
K ++ + +KE+ ++ E+ +Q R+ ++ E W+ K + +Y +
Sbjct: 3922 EKLLELSELMKKVKESWNVRKELYEENWEIQLLRRELEQAEAWLAAKESFLSDPSYGVSK 3981
Query: 2673 DPTNI 2659
D T +
Sbjct: 3982 DSTTV 3986
Score = 363 bits (932), Expect = 3e-98
Identities = 307/1437 (21%), Positives = 622/1437 (42%), Gaps = 90/1437 (6%)
Frame = -1
Query: 5403 LQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKK 5224
++KH FE+ L + + ++ ++ ++ G I +L + ++ + + +
Sbjct: 2565 IRKHEAFEKLLASQDEKITSLQEQANKLEKDGGLDGVQIQHKLDTILQRKKQIKNLSRSR 2624
Query: 5223 GAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLI------E 5062
KL+ A F +N+ + E W+SE ++ ED + NLQ K+ L+ E
Sbjct: 2625 REKLQTALLLALFYQNLAEAEDWISERMQKL--ED--PSIQDPSNLQDKMKLLQKHQVFE 2680
Query: 5061 SDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESH 4882
++ A+ + + + + + H + I R+ LQ+R+ L+ + R + L +S
Sbjct: 2681 AEILANEEIITDVNKKGEALVSMGHPKSGEIRRQVRMLQERWEKLKRAVAARGKMLEDSR 2740
Query: 4881 QGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKK------------------- 4759
+ + ++ AWIREKE + + G D LI+K
Sbjct: 2741 DFLEFLQKVDQVEAWIREKEVMINIGDVGNDYEHCLQLIRKLNEFRGATSGLPGEETEVS 2800
Query: 4758 QQAL------------------------IAEIANHDSQIESVSSAANDMIQQGHFLAPEI 4651
++A+ I E D+ I+++++ A + +Q I
Sbjct: 2801 EEAICGCLLVYLVYFVAVRNTEVHMEIDILETTVDDAHIKAINALAMKLERQNKEETKTI 2860
Query: 4650 RDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKD 4471
+ QL + W R L+ +L+ H + + ++ ++EK ++ + DYGKD
Sbjct: 2861 YQRRKQLNEKWNSFHGNLNAYRRKLEGALEIHALIREIDDITERITEKSVLIQALDYGKD 2920
Query: 4470 EDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQC-------------KYQE-------- 4354
+S E L+++H + ++ K IE L ++ + K QE
Sbjct: 2921 VESVENLIRRHEEMEREINVIKSKIEPLELESFRLSTRNPSINDKLTMKQQEMKNNWLRL 2980
Query: 4353 QPMGQLGRDCVLALYDYQE--KSPREVSMKKGDVLTLLNAS------NRDWWKVEVNDRQ 4198
Q + ++ + A Y Q+ +E++ ++ L+ A N +E + ++
Sbjct: 2981 QGQAKQRKEKLAASYQLQKFNSEMKEITDWIQNIRGLMEAGGLPKSLNEAESMIEEHQQR 3040
Query: 4197 GFVPAAYVKRIEPGTAQQHAQQQVNS-------IGGKQSEIEDKYQRLMMLGETRKRKLE 4039
A V+R + + QQ NS I S ++ + L+ + + KL
Sbjct: 3041 KEEIEARVERFN--SLSNYGQQLANSGHYATPEIHQSLSRLQKAWTELIQAWQEQYIKLF 3098
Query: 4038 EACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQ 3859
+A + W+ S+EA A +++G + VE LQ+K F+ L+A ++
Sbjct: 3099 QAQDLQKFYGYVEQTESWLSSKEAFLANEDLGDSVSSVESLQRKHMQFEKSLEAQMEKID 3158
Query: 3858 EMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVD 3679
EM A L ++ I + + + R L L + +Q+ ++
Sbjct: 3159 EMASFAQQLIQNKHYDSD-NITNRCQAVLRRKEKLLENAAARRHLLEESRLLQKLLKNSY 3217
Query: 3678 ETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSH 3499
E WI EK+ ++ +D RD ++Q +KH+ + ++ A +++ S+ + ++ +
Sbjct: 3218 EVATWINEKN-SIAQDDSWRDPSNLQTKLQKHQSFQAEIMANKNRLDSIKSEGEKMIRER 3276
Query: 3498 PEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVS 3319
A E I +E+ E W L + +++ KL D+Y F D +W+ + +
Sbjct: 3277 HYAPEAIQSRLQEMEELWEELLASCQDKRAKLQDAYKALHFQRSIEDTEKWLEDVENELK 3336
Query: 3318 SQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGV 3139
+ ++D+ + L++ +E +I S Q + H+ A ++E R+ +
Sbjct: 3337 APYSSDDLVVLNSHLKKQEELEQDIASHRDRLQELVNTAQEFQQEKHFLADELEERVDQL 3396
Query: 3138 NEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQED--PSGDNVESL 2965
+ K L D RR L+ F+RD ++ W+ + + D S V+SL
Sbjct: 3397 VQRYKSLRDPLQERRGSLEASRLQYEFFRDVDEELAWVHEKLPMASSRDYGQSLATVQSL 3456
Query: 2964 IKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQK 2785
+KH++ + I++++ K + + L++ H S + + ++ LK +
Sbjct: 3457 QEKHQNLENEISSRDALTKAVLSTGQKLVRGGHSASRKIMEQMKELETSVENLKAEAHVR 3516
Query: 2784 RFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENY-RDPTNIQQKHQKQQAFEAELHAN 2608
R +L +S QF + ++E W+ E+ I + +Y ++ + Q +K +A + ++
Sbjct: 3517 RQRLMQSYEAHQFLTELLDVETWLAERSFILETSDYGKNEESTQALLRKLEATKLDMEGF 3576
Query: 2607 SDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKS 2428
RI + + G +LI N A +S + L D LL K T++ RL+E +
Sbjct: 3577 RPRIEKVQETGASLI-NKDNPESPAILSKLQRILADYQSLLQKAETQRK-RLQEQFQLYQ 3634
Query: 2427 FMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADI--VAHQDRVGEMNEQ 2254
F + ++ WL + + +S+DYG+DL VE L KK +I + H +V +NE
Sbjct: 3635 FEREFQLVDAWLSSKQSIAESDDYGQDLDGVEVLEKKFKDFVNEIKPLGHS-KVLSLNEL 3693
Query: 2253 ADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWI 2074
A L ++ + I +R K I + ++ + R + L A VHQ+ D+D+ + W+
Sbjct: 3694 ASKLEKDGHSKTDIIQKRTKQINEMWEKLCHAIQTRTENLRAAQQVHQYDHDVDEVKGWM 3753
Query: 2073 KEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVG 1894
+EK+ +V DDYG DLPGVQ L + ++ +L + ++ ++ + L R+ +
Sbjct: 3754 QEKEAVVDIDDYGYDLPGVQTLLSQLEGVERDLGAIMKELERIRGEAWHLSRTYPQL--- 3810
Query: 1893 EDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDN 1714
++ I +R+ D+++ W + R RL ++E Q + D E AW NE ++ S+
Sbjct: 3811 KENIMERLTDVDECWRNLDKKFLERKARLSQAEQVQLYFNDCRELMAWANEMHALVISEE 3870
Query: 1713 FGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRAR 1534
++ G + L+K+HD ++ ++E + ++ GD L NG+ + I+++ +L
Sbjct: 3871 LANDVLGAELLIKRHDEYKREIEKQWLKYEEIQRAGDDLTRNGHFMSVEIEEKLLELSEL 3930
Query: 1533 LIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQIL 1363
+ +++ R +N + + E+W+A KE + +G S +L
Sbjct: 3931 MKKVKESWNVRKELYEENWEIQLLRRELEQAEAWLAAKESFLSDPSYGVSKDSTTVL 3987
Score = 352 bits (904), Expect = 6e-95
Identities = 352/1699 (20%), Positives = 723/1699 (41%), Gaps = 97/1699 (5%)
Frame = -1
Query: 7176 QEVLGHYSIFK--DHS-----QTKRDRLEEARQF-QYFKRDADELNVWILEKLQTAQEEN 7021
Q+V H+ I + +H+ Q + RLE+ Q + F + A ++ + + +++
Sbjct: 457 QDVEKHWIILEKAEHNRGKALQKEMLRLEKLEQLAKRFLKKAALRETYLEDMRKVIGKQD 516
Query: 7020 FRDPS--NLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHA 6847
F S ++A +K EA A+V + A+L + + Q+N+ + + I K+ +
Sbjct: 517 FWPESVDRMEAASKKLEAIVADVLPRRERFASLAEMATVISQNNYHSKDQIVKKENSISK 576
Query: 6846 LWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQR 6667
W + L ++L +R D I+ ++E + V ++D G L V L +
Sbjct: 577 QWQDLLDQLQKRQHSLSTMQEILALLRDIDAIMEELKELQALVNSQDCGKQLLEVVDLLQ 636
Query: 6666 KFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKE 6487
K + ++ ++ ++ I Q ++ ++ + + +Y K + + L + TRK
Sbjct: 637 KHNLIDLQISSYDDKLTHITQRTAEISKDSTVKAEVLYAKVPMLRQLYQNLIAQSRTRKS 696
Query: 6486 GLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEG 6307
L A ++ F RD E AWI EK + G+D++ + A +KH+ E + +
Sbjct: 697 QLEEALKLFEFFRDCKEEEAWISEKWKIARTTTLGKDVSQITASIQKHKALEAECNSHRA 756
Query: 6306 KMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLAD 6127
+ + L++ +P E I ++ D + W L+++ +RK+ L+ + + ++ AD
Sbjct: 757 ICADVMRRGWDLSQKNPTHEENIQKQRDKLQTLWQQLQDEVANRKNRLQAAALIKQYFAD 816
Query: 6126 YRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARA--------------- 5992
+ SW+ + + ++ + + KD + AEALL H + EI A +
Sbjct: 817 IDEANSWLQERQTLVASKDYGKDESSAEALLHRHLRLEKEIAAYSTEMRRLKEQAAIAAE 876
Query: 5991 ------------DSFNQTA-----SAGQKLVEMGIPES--------PE-VQEKLEKLDHE 5890
D NQ S E +P S PE + + +++D
Sbjct: 877 QAPAAMVKTEAPDDLNQKTAKLPFSRTWATSESALPGSSSLDIHFVPENIWKTQDEIDSL 936
Query: 5889 KSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKK 5710
+L + E+R+ E+ ++ F E ++WM ++E L D+VE + +K
Sbjct: 937 YENLQSMAEDRKKALEEMIEYYRFCSSCEAFQSWMREKENIFRT--LQPQADNVEVMQQK 994
Query: 5709 HEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNA 5530
++ F LAA + ++ ++ ATK + ++ +G+
Sbjct: 995 YQSFLTELAAGKGQLGEIESLATKFGKNSPGKYTEIQIWLKEIHARWQHMESLKEEKGSE 1054
Query: 5529 LKESYKRQTFDRDCDEMVSWITEKLSTARD-DSYLDPTNIRGKLQKHINFEQELKANENR 5353
L +TF DC + + +K+ R+ + P + +K E+E+ E +
Sbjct: 1055 LIGVADVRTFLEDCQSIGVLLQDKMGQLRNLEPGNSPAGLESDKRKLSVVEREILVIERK 1114
Query: 5352 LDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNI 5173
++ +RS + I D+ + I ++ + +L L T +K L++A N+Q F ++
Sbjct: 1115 IEYLRSVAKSIKDTNPAESKAITVQVENMESLLVNLKLETQRKRDLLQQAQNQQSFLQDS 1174
Query: 5172 EDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEE 4993
+ W + ++ SE+ G D+ S ++L ++ + + + +R +++L ++ ++
Sbjct: 1175 RRLLLWAEGIREKLRSEEMGVDVASAEHLLREHQDLLKEIRSQKERFLQLEELGRKIIQK 1234
Query: 4992 EHFNAPV--IVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQ 4819
+ N+ + E L + L + E+R +KL + + + R+ + A + E
Sbjct: 1235 QPSNSRTRDVHLSVERLAEENKELENMWEQRWKKLQDGLELQKFNREGDRINAALSSHEA 1294
Query: 4818 VAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKL 4639
+ G + V++L K+ Q + +IE+ + D+I+ GHF + I++++
Sbjct: 1295 FLRGDDLGDHVDAVRSLQKQHQEFEQLLMVLKRRIEAFNENGADLIESGHFASHAIKERM 1354
Query: 4638 AQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSA 4459
A LR W L KR+ L DSLQ ++ DA E WM EK I Y +D +
Sbjct: 1355 ATLRQRWERLVENNSKRKQRLLDSLQLQEFNRDAAELLIWMEEKYKIASDESY-RDPTNV 1413
Query: 4458 EALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQPMGQLGRDCVLALYDYQEKSPREV 4279
LK H A ++ A + L K+ +Q Q+ ++ + + K
Sbjct: 1414 LRKLKWHEAAEKEMMANEKHFITLIKKGNQL-IQDDHYAAASIQKKMSELEKKWKELYGK 1472
Query: 4278 SMKKGD----------VLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIEPGTAQQHAQ-- 4135
+++GD ++ LL + + K+E ++ + R +QH Q
Sbjct: 1473 MIERGDKLRQAGQQEQLMELLQDAKKKIEKIEKVLQE--AETGHDLRSSRDLLKQHRQLE 1530
Query: 4134 -------QQVNSIGG----------KQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLRE 4006
+++NSI I D+ Q+ + E+ + L+E K LL
Sbjct: 1531 NETHELAEKMNSIVSHAMKMATNHFDSQRILDETQKYLKRFESLQAPLDERRK---LLEA 1587
Query: 4005 ANDLAE----------WIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQE 3856
A DL E WI R +A+ G L+ + L +K +F+ ++ A++ ++Q
Sbjct: 1588 AVDLYEFYHYHDMELNWINERLPIASSTNCGKSLDVAQSLLQKHKEFQAEVNAHKQQVQR 1647
Query: 3855 MNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDE 3676
+ + V Q +A +I ++ ++L W+ L QL + Q F + +
Sbjct: 1648 VLDKGRTMI-VNQHPSAQKINEKCQELVTAWQGLEKACEERTKQLQHSVGFQEFLMNTSD 1706
Query: 3675 TRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHP 3496
WI EK + S+D+G+D L +KH+ +E ++A D IK L+E L
Sbjct: 1707 LEAWIAEKRPLVMSKDYGKDEDGTLKLLQKHKVLEHEIAVYQDLIKELNESVQNLPAMGS 1766
Query: 3495 EAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSS 3316
++ + +++ + L A R +KL ++ FL +Y DL W+A Q SS
Sbjct: 1767 IQYVEVDAPREQVHSRLRELQELAATRGKKLDETLVLHEFLREYEDLQDWMAQQKQAASS 1826
Query: 3315 QELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVN 3136
++ N+ L ++ +R ++++ Q LLN+ H + +I + + +
Sbjct: 1827 EDYGNNYEHVLQLRAKYDTFRHQLEATGKRVMTCQQLAENLLNAGHSESREIRQKQKDLR 1886
Query: 3135 EARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGD--NVESLI 2962
+ + L + R L + Y+D A + + + +D + D V++ +
Sbjct: 1887 NSWEELLEITRLRGERLKDAEVIHKCYQDLTDALAHIEEKSKSI-PDDVAKDMRGVQTQL 1945
Query: 2961 KKHEDFDKAINTQEEKIKGLKLFAES-LIKNNHYDSPAVTRKRDQILDRWNGLKEALIQK 2785
+ H + + E++++ L A+ L + ++ + + K+ I+ W LK + +
Sbjct: 1946 RNHVALEHELLGNEQQLQDLIHSADHVLTRCSNEQASGLKAKQQAIVTNWKALKSKVQLR 2005
Query: 2784 RFKLGESQTLQQFSRDADEIENWMTEKF-QIAQEENYRDPTNIQQKHQKQQAFEAELHAN 2608
+ L ++ L QF + +W +E ++ +E RD + + + Q AE+ A
Sbjct: 2006 KELLEQAHKLYQFQAQVWDYFSWTSEMIREMRAKETIRDISTSSLRLTQHQQLLAEIEAQ 2065
Query: 2607 SDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKS 2428
++ I+Q G +L+++ + E + +L+AL ++ D + +K L ++++
Sbjct: 2066 EEKYNQIVQLGQSLLQDEEIRSKE--IRQKLQALLEEKDKVYSEWQQKKKWLDRIHQEQM 2123
Query: 2427 FMAAVKDLEFWLGEVEILL 2371
F L+ L E +L
Sbjct: 2124 FYKDWNHLDKLLNSQEEML 2142
Score = 317 bits (812), Expect = 3e-84
Identities = 206/804 (25%), Positives = 376/804 (46%), Gaps = 2/804 (0%)
Frame = -1
Query: 7200 ADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEEN 7021
+D+I R Q VL +++ +R LEE+R Q +++ E+ WI EK AQ+++
Sbjct: 3175 SDNITNRCQAVLRRKEKLLENAAARRHLLEESRLLQKLLKNSYEVATWINEKNSIAQDDS 3234
Query: 7020 FRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALW 6841
+RDPSNLQ K+QKH++F+AE+ A+ + ++ G MI+ H+A E I+ RL+E+ LW
Sbjct: 3235 WRDPSNLQTKLQKHQSFQAEIMANKNRLDSIKSEGEKMIRERHYAPEAIQSRLQEMEELW 3294
Query: 6840 XXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKF 6661
K KLQ A K LHF R ++ W+ + E + A DL + +K
Sbjct: 3295 EELLASCQDKRAKLQDAYKALHFQRSIEDTEKWLEDVENELKAPYSSDDLVVLNSHLKKQ 3354
Query: 6660 DDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGL 6481
++ +++ +H+ R+ E+ A + +E H D++ ++ D + + L R+ L
Sbjct: 3355 EELEQDIASHRDRLQELVNTAQEFQQEKHFLADELEERVDQLVQRYKSLRDPLQERRGSL 3414
Query: 6480 FGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKM 6301
+ F RD DE LAW+ EK SS DYG+ L VQ+LQ KH+ E ++++ +
Sbjct: 3415 EASRLQYEFFRDVDEELAWVHEKLPMASSRDYGQSLATVQSLQEKHQNLENEISSRDALT 3474
Query: 6300 LQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYR 6121
+ KL + I ++ + + + LK +A R+ L +S++ H+FL +
Sbjct: 3475 KAVLSTGQKLVRGGHSASRKIMEQMKELETSVENLKAEAHVRRQRLMQSYEAHQFLTELL 3534
Query: 6120 DLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMG 5941
D+ +W+ + ++ + K+ +ALL + K +++ + G L+
Sbjct: 3535 DVETWLAERSFILETSDYGKNEESTQALLRKLEATKLDMEGFRPRIEKVQETGASLINKD 3594
Query: 5940 IPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLA 5761
PESP + KL+++ + SLL E +R ++ L F R+ + + W++ +++
Sbjct: 3595 NPESPAILSKLQRILADYQSLLQKAETQRKRLQEQFQLYQFEREFQLVDAWLSSKQSIAE 3654
Query: 5760 NTDLGDSLDSVEHLIKKHEDFEKSL-AAQEEKINALDEFATKLIQGQHYAADDVAEXXXX 5584
+ D G LD VE L KK +DF + K+ +L+E A+KL + H D + +
Sbjct: 3655 SDDYGQDLDGVEVLEKKFKDFVNEIKPLGHSKVLSLNELASKLEKDGHSKTDIIQKRTKQ 3714
Query: 5583 XXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSY-LDPTNIRG 5407
R L+ + + +D D DE+ W+ EK + D Y D ++
Sbjct: 3715 INEMWEKLCHAIQTRTENLRAAQQVHQYDHDVDEVKGWMQEKEAVVDIDDYGYDLPGVQT 3774
Query: 5406 KLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNK 5227
L + E++L A L+ IR + + ++I +RL V+ W L +
Sbjct: 3775 LLSQLEGVERDLGAIMKELERIRGEAWHLSRTYPQLKENIMERLTDVDECWRNLDKKFLE 3834
Query: 5226 KGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNA 5047
+ A+L +A Q + + ++ AW +E+ V SE+ D++ + L K+ + +
Sbjct: 3835 RKARLSQAEQVQLYFNDCRELMAWANEMHALVISEELANDVLGAELLIKRHDEYKREIEK 3894
Query: 5046 HNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQL 4867
+ + I++ HF + I K L + +++ RK E+ + L
Sbjct: 3895 QWLKYEEIQRAGDDLTRNGHFMSVEIEEKLLELSELMKKVKESWNVRKELYEENWEIQLL 3954
Query: 4866 FRDIEDELAWIREKEQVAGSTNRG 4795
R++E AW+ KE + G
Sbjct: 3955 RRELEQAEAWLAAKESFLSDPSYG 3978
Score = 299 bits (766), Expect = 6e-79
Identities = 281/1466 (19%), Positives = 621/1466 (42%), Gaps = 102/1466 (6%)
Frame = -1
Query: 6402 LSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETHPDRAEAIHQKND 6223
L S D G ++ V+ L RKHE E+ LA+ + K+ L+++A+KL + I K D
Sbjct: 2549 LKSSDLGSSVDEVEQLIRKHEAFEKLLASQDEKITSLQEQANKLEKDGGLDGVQIQHKLD 2608
Query: 6222 DTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAE 6043
+K ++ R++ L+ + L F + + WI + + D +D + +
Sbjct: 2609 TILQRKKQIKNLSRSRREKLQTALLLALFYQNLAEAEDWISERMQKL-EDPSIQDPSNLQ 2667
Query: 6042 ---ALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLG 5872
LL+ HQ + EI A + G+ LV MG P+S E++ ++ L L
Sbjct: 2668 DKMKLLQKHQVFEAEILANEEIITDVNKKGEALVSMGHPKSGEIRRQVRMLQERWEKLKR 2727
Query: 5871 LWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVEHLIKKHEDFE- 5695
R + E D F + +Q E W+ ++E + D+G+ + LI+K +F
Sbjct: 2728 AVAARGKMLEDSRDFLEFLQKVDQVEAWIREKEVMINIGDVGNDYEHCLQLIRKLNEFRG 2787
Query: 5694 --KSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXXXRGNALKE 5521
L +E +++ L+ ++ A E NAL
Sbjct: 2788 ATSGLPGEETEVSEEAICGCLLVYLVYFVAVRNTEVHMEIDILETTVDDAHIKAINALAM 2847
Query: 5520 SYKRQTFD----------------------------------------RDCDEMVSWITE 5461
+RQ + R+ D++ ITE
Sbjct: 2848 KLERQNKEETKTIYQRRKQLNEKWNSFHGNLNAYRRKLEGALEIHALIREIDDITERITE 2907
Query: 5460 KLSTARDDSY-LDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIG 5284
K + Y D ++ +++H E+E+ +++++ + ++ D +
Sbjct: 2908 KSVLIQALDYGKDVESVENLIRRHEEMEREINVIKSKIEPLELESFRLSTRNPSINDKLT 2967
Query: 5283 DRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDL 5104
+ +++ N W L ++ KL + Q+FN ++++ W+ + G + + K L
Sbjct: 2968 MKQQEMKNNWLRLQGQAKQRKEKLAASYQLQKFNSEMKEITDWIQNIRGLMEAGGLPKSL 3027
Query: 5103 VSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALR 4924
+++ ++ + + A +R + + QQ H+ P I + LQ+ + L
Sbjct: 3028 NEAESMIEEHQQRKEEIEARVERFNSLSNYGQQLANSGHYATPEIHQSLSRLQKAWTELI 3087
Query: 4923 DPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALI 4744
+++ KL ++ + + +E +W+ KE + + G + V++L +K
Sbjct: 3088 QAWQEQYIKLFQAQDLQKFYGYVEQTESWLSSKEAFLANEDLGDSVSSVESLQRKHMQFE 3147
Query: 4743 AEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKL-AQLRDNWRILKSKAEKRRTDLDDS 4567
+ +I+ ++S A +IQ H+ + I ++ A LR ++L++ A +R L++S
Sbjct: 3148 KSLEAQMEKIDEMASFAQQLIQNKHYDSDNITNRCQAVLRRKEKLLENAAARRHL-LEES 3206
Query: 4566 LQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDL 4387
+ L ++ E W++EK I D +D + + L+KH++ +++ A K ++ +
Sbjct: 3207 RLLQKLLKNSYEVATWINEKNSI-AQDDSWRDPSNLQTKLQKHQSFQAEIMANKNRLDSI 3265
Query: 4386 RK-------------QASQCKYQEQPMGQLGRDCVLALYDYQ------------------ 4300
+ +A Q + QE M +L + + + D +
Sbjct: 3266 KSEGEKMIRERHYAPEAIQSRLQE--MEELWEELLASCQDKRAKLQDAYKALHFQRSIED 3323
Query: 4299 -EKSPREVSMK-----KGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIEP--GTAQQ 4144
EK +V + D L +LN+ + ++E + A++ R++ TAQ+
Sbjct: 3324 TEKWLEDVENELKAPYSSDDLVVLNSHLKKQEELEQD------IASHRDRLQELVNTAQE 3377
Query: 4143 HAQQQ---VNSIGGKQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSR 3973
Q++ + + + ++ +Y+ L + R+ LE + Y+ R+ ++ W+ +
Sbjct: 3378 FQQEKHFLADELEERVDQLVQRYKSLRDPLQERRGSLEASRLQYEFFRDVDEELAWVHEK 3437
Query: 3972 EAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIR 3793
+A+ ++ G L V+ LQ+K + + ++ + + + + L G + + +I
Sbjct: 3438 LPMASSRDYGQSLATVQSLQEKHQNLENEISSRDALTKAVLSTGQKLVRGGHSASR-KIM 3496
Query: 3792 QQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDL 3613
+Q+++L L +L ++E +F ++ + W+ E+ L++ D+G++
Sbjct: 3497 EQMKELETSVENLKAEAHVRRQRLMQSYEAHQFLTELLDVETWLAERSFILETSDYGKNE 3556
Query: 3612 RSVQALQRKHEGVERDLAALGDKIKSLDEK-ANRLRQSHPEAAEQIYDLQRELNEQWNRL 3436
S QAL RK E + D+ +I+ + E A+ + + +PE+ + LQR L + + L
Sbjct: 3557 ESTQALLRKLEATKLDMEGFRPRIEKVQETGASLINKDNPESPAILSKLQRILAD-YQSL 3615
Query: 3435 TSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEY 3256
KA ++++L + + +F +++ + W++S + S + D+ G E L ++ +++
Sbjct: 3616 LQKAETQRKRLQEQFQLYQFEREFQLVDAWLSSKQSIAESDDYGQDLDGVEVLEKKFKDF 3675
Query: 3255 RTEIDSRA-ATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQ 3079
EI + + ++ ++L H I+ R + +NE + L A R L
Sbjct: 3676 VNEIKPLGHSKVLSLNELASKLEKDGHSKTDIIQKRTKQINEMWEKLCHAIQTRTENLRA 3735
Query: 3078 CLELQLFYRDCEQADTWMSAREAFLAQEDPSGD--NVESLIKKHEDFDKAINTQEEKIKG 2905
++ + D ++ WM +EA + +D D V++L+ + E ++ + ++++
Sbjct: 3736 AQQVHQYDHDVDEVKGWMQEKEAVVDIDDYGYDLPGVQTLLSQLEGVERDLGAIMKELER 3795
Query: 2904 LKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEI 2725
++ A L + + + + + W L + ++++ +L +++ +Q + D E+
Sbjct: 3796 IRGEAWHLSRTYPQLKENIMERLTDVDECWRNLDKKFLERKARLSQAEQVQLYFNDCREL 3855
Query: 2724 ENWMTEKFQ-IAQEENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKC 2548
W E + EE D + ++ ++ E+ + I +AG++L N
Sbjct: 3856 MAWANEMHALVISEELANDVLGAELLIKRHDEYKREIEKQWLKYEEIQRAGDDLTRNGHF 3915
Query: 2547 GGGE-----AAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEV 2383
E +S +K + + W++ K E+++ ++ ++ ++ E WL
Sbjct: 3916 MSVEIEEKLLELSELMKKVKESWNVR-KELYEENWEIQLLRRE------LEQAEAWLAAK 3968
Query: 2382 EILLQSEDYG--KDLASVENLLKKHS 2311
E L YG KD +V L H+
Sbjct: 3969 ESFLSDPSYGVSKDSTTVLKCLLVHT 3994
Score = 294 bits (753), Expect = 2e-77
Identities = 200/920 (21%), Positives = 406/920 (43%), Gaps = 5/920 (0%)
Frame = -1
Query: 7194 DIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENFR 7015
+IHQ + ++ Q + +L +A+ Q F ++ W+ K E+
Sbjct: 3071 EIHQSLSRLQKAWTELIQAWQEQYIKLFQAQDLQKFYGYVEQTESWLSSKEAFLANEDLG 3130
Query: 7014 DP-SNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWX 6838
D S++++ +KH FE ++A + I + +IQ+ H+ S++I R + +
Sbjct: 3131 DSVSSVESLQRKHMQFEKSLEAQMEKIDEMASFAQQLIQNKHYDSDNITNRCQAVLRRKE 3190
Query: 6837 XXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFD 6658
+ L+++ L ++ E+ WI EK + + +D D +++ +K
Sbjct: 3191 KLLENAAARRHLLEESRLLQKLLKNSYEVATWINEKNS-IAQDDSWRDPSNLQTKLQKHQ 3249
Query: 6657 DFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLF 6478
F E+ ++ R++ I +K++ E H + I + ++ + W L ++ L
Sbjct: 3250 SFQAEIMANKNRLDSIKSEGEKMIRERHYAPEAIQSRLQEMEELWEELLASCQDKRAKLQ 3309
Query: 6477 GAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKML 6298
A++ F R ++T W+ + + L + DL + + +K E E+D+A+ ++
Sbjct: 3310 DAYKALHFQRSIEDTEKWLEDVENELKAPYSSDDLVVLNSHLKKQEELEQDIASHRDRLQ 3369
Query: 6297 QLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRD 6118
+L A + + A+ + ++ D + +L++ Q R+ LE S + F D +
Sbjct: 3370 ELVNTAQEFQQEKHFLADELEERVDQLVQRYKSLRDPLQERRGSLEASRLQYEFFRDVDE 3429
Query: 6117 LISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGI 5938
++W+ + + + + + +A ++L E HQ + EI +R S GQKLV G
Sbjct: 3430 ELAWVHEKLPMASSRDYGQSLATVQSLQEKHQNLENEISSRDALTKAVLSTGQKLVRGGH 3489
Query: 5937 PESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLAN 5758
S ++ E++++L+ +L RR Q + F + ETW+ ++ L
Sbjct: 3490 SASRKIMEQMKELETSVENLKAEAHVRRQRLMQSYEAHQFLTELLDVETWLAERSFILET 3549
Query: 5757 TDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXX 5578
+D G + +S + L++K E + + +I + E LI + + +
Sbjct: 3550 SDYGKNEESTQALLRKLEATKLDMEGFRPRIEKVQETGASLINKDNPESPAILSKLQRIL 3609
Query: 5577 XXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSY---LDPTNIRG 5407
+ L+E ++ F+R+ + +W++ K S A D Y LD +
Sbjct: 3610 ADYQSLLQKAETQRKRLQEQFQLYQFEREFQLVDAWLSSKQSIAESDDYGQDLDGVEVLE 3669
Query: 5406 KLQKHINFEQELKA-NENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATN 5230
K K +F E+K +++ + ++ GH D I R +Q+N +W +L A
Sbjct: 3670 K--KFKDFVNEIKPLGHSKVLSLNELASKLEKDGHSKTDIIQKRTKQINEMWEKLCHAIQ 3727
Query: 5229 KKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFN 5050
+ LR A Q++ ++++V+ W+ E E V +DYG DL VQ L ++ +E D
Sbjct: 3728 TRTENLRAAQQVHQYDHDVDEVKGWMQEKEAVVDIDDYGYDLPGVQTLLSQLEGVERDLG 3787
Query: 5049 AHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQ 4870
A ++ I+ A I+ + ++ + + L +RK +L ++ Q
Sbjct: 3788 AIMKELERIRGEAWHLSRTYPQLKENIMERLTDVDECWRNLDKKFLERKARLSQAEQVQL 3847
Query: 4869 LFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAAN 4690
F D + +AW E + S D++G + LIK+ EI + E + A +
Sbjct: 3848 YFNDCRELMAWANEMHALVISEELANDVLGAELLIKRHDEYKREIEKQWLKYEEIQRAGD 3907
Query: 4689 DMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSE 4510
D+ + GHF++ EI +KL +L + + +K R+ +++ + + +A+AW++
Sbjct: 3908 DLTRNGHFMSVEIEEKLLELSELMKKVKESWNVRKELYEENWEIQLLRRELEQAEAWLAA 3967
Query: 4509 KEPIVGSTDYGKDEDSAEAL 4450
KE + YG +DS L
Sbjct: 3968 KESFLSDPSYGVSKDSTTVL 3987
Score = 247 bits (630), Expect = 4e-63
Identities = 216/958 (22%), Positives = 423/958 (43%), Gaps = 18/958 (1%)
Frame = -1
Query: 7191 IHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENFRD 7012
I +R + + +++ ++ RL ++ Q Q F RDA EL +W+ EK + A +E++RD
Sbjct: 1350 IKERMATLRQRWERLVENNSKRKQRLLDSLQLQEFNRDAAELLIWMEEKYKIASDESYRD 1409
Query: 7011 PSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXX 6832
P+N+ K++ HEA E E+ A+ K L K GN +IQ +H+A+ I+K++ EL W
Sbjct: 1410 PTNVLRKLKWHEAAEKEMMANEKHFITLIKKGNQLIQDDHYAAASIQKKMSELEKKWKEL 1469
Query: 6831 XXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDF 6652
+G KL+QA + + + I + E + + G DL R D
Sbjct: 1470 YGKMIERGDKLRQAGQQEQLMELLQDAKKKIEKIEKVLQEAETGHDL-------RSSRDL 1522
Query: 6651 LKELGNHQYRINEINQAADKL---------VEEGHSEHDQIYKKRDDVNDAWHRLNTLAA 6499
LK+ H+ NE ++ A+K+ + H + +I + + L
Sbjct: 1523 LKQ---HRQLENETHELAEKMNSIVSHAMKMATNHFDSQRILDETQKYLKRFESLQAPLD 1579
Query: 6498 TRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLA 6319
R++ L A + F D L WI E+ SS + G+ L+ Q+L +KH+ + ++
Sbjct: 1580 ERRKLLEAAVDLYEFYHYHDMELNWINERLPIASSTNCGKSLDVAQSLLQKHKEFQAEVN 1639
Query: 6318 ALEGKMLQ-LEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLH 6142
A + ++ + L+K + HP A+ I++K + AW L++ + R L+ S
Sbjct: 1640 AHKQQVQRVLDKGRTMIVNQHPS-AQKINEKCQELVTAWQGLEKACEERTKQLQHSVGFQ 1698
Query: 6141 RFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAG 5962
FL + DL +WI + + ++ + + KD G LL+ H+ + EI D + +
Sbjct: 1699 EFLMNTSDLEAWIAEKRPLVMSKDYGKDEDGTLKLLQKHKVLEHEIAVYQDLIKELNESV 1758
Query: 5961 QKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMN 5782
Q L MG + EV E++ L L R ++ + L F R+ E + WM
Sbjct: 1759 QNLPAMGSIQYVEVDAPREQVHSRLRELQELAATRGKKLDETLVLHEFLREYEDLQDWMA 1818
Query: 5781 KQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDV 5602
+Q+ ++ D G++ + V L K++ F L A +++ + A L+ H + ++
Sbjct: 1819 QQKQAASSEDYGNNYEHVLQLRAKYDTFRHQLEATGKRVMTCQQLAENLLNAGHSESREI 1878
Query: 5601 AEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDP 5422
+ RG LK++ +D + ++ I EK + DD D
Sbjct: 1879 RQKQKDLRNSWEELLEITRLRGERLKDAEVIHKCYQDLTDALAHIEEKSKSIPDDVAKDM 1938
Query: 5421 TNIRGKLQKHINFEQELKANENRLDDIRSTGEQIID-SGHFAADHIGDRLRQVNNLWNEL 5245
++ +L+ H+ E EL NE +L D+ + + ++ + A + + + + W L
Sbjct: 1939 RGVQTQLRNHVALEHELLGNEQQLQDLIHSADHVLTRCSNEQASGLKAKQQAIVTNWKAL 1998
Query: 5244 VDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLI 5065
+ L +A QF + D +W SE+ ++ +++ +D+ + + +
Sbjct: 1999 KSKVQLRKELLEQAHKLYQFQAQVWDYFSWTSEMIREMRAKETIRDISTSSLRLTQHQQL 2058
Query: 5064 ESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGES 4885
++ A ++ + I QL Q ++E + I +K + L + + + +++K+ L
Sbjct: 2059 LAEIEAQEEKYNQIVQLGQSLLQDEEIRSKEIRQKLQALLEEKDKVYSEWQQKKKWLDRI 2118
Query: 4884 HQGNQLFRDIE--DELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIE 4711
HQ ++D D+L +E+ V S ++ + V L + +H ++
Sbjct: 2119 HQEQMFYKDWNHLDKLLNSQEEMLVFTSVSKA---VSVYRLSCRMSC-----RDHRCKLS 2170
Query: 4710 SVS---SAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLS- 4543
SV S A M+ P + + Q R ++ + + + +Q + S
Sbjct: 2171 SVPVYVSTAEVMLSPSGMTPPPPFESIVQDRPFQKMPPTARHAPTGRVAEIIQGNASSSP 2230
Query: 4542 DANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEA-FKGTIEDLRKQAS 4372
++ + A+ S + ++ TD+ K +A H A LSD +A + + +D +++ S
Sbjct: 2231 NSVSSGAYCSRLDVVLEHTDWRKGLGNA-----SHCADLSDRKARWSSSPKDTQRRGS 2283
Score = 243 bits (620), Expect = 5e-62
Identities = 245/1255 (19%), Positives = 520/1255 (40%), Gaps = 92/1255 (7%)
Frame = -1
Query: 4668 FLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQ--------AHQYLSDANEADAWMS 4513
++ PE R L + +W IL+ R L + A ++L A + ++
Sbjct: 448 YVPPEGRT-LQDVEKHWIILEKAEHNRGKALQKEMLRLEKLEQLAKRFLKKAALRETYLE 506
Query: 4512 EKEPIVGSTDYGKDE-DSAEALLKKHRALLSDLEAFKGTIEDLRKQA---SQCKY----- 4360
+ ++G D+ + D EA KK A+++D+ + L + A SQ Y
Sbjct: 507 DMRKVIGKQDFWPESVDRMEAASKKLEAIVADVLPRRERFASLAEMATVISQNNYHSKDQ 566
Query: 4359 ---QEQPMGQLGRDCVLALYDYQEKSPREVSMKKGDVLTLLN---------------ASN 4234
+E + + +D L D +K +S + ++L LL ++
Sbjct: 567 IVKKENSISKQWQD----LLDQLQKRQHSLSTMQ-EILALLRDIDAIMEELKELQALVNS 621
Query: 4233 RDWWK-----VEVNDRQGFVP---AAY---VKRIEPGTAQQHAQQQVNS--IGGKQSEIE 4093
+D K V++ + + ++Y + I TA+ V + + K +
Sbjct: 622 QDCGKQLLEVVDLLQKHNLIDLQISSYDDKLTHITQRTAEISKDSTVKAEVLYAKVPMLR 681
Query: 4092 DKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQ 3913
YQ L+ TRK +LEEA K ++ R+ + WI + +A +G D+ Q+
Sbjct: 682 QLYQNLIAQSRTRKSQLEEALKLFEFFRDCKEEEAWISEKWKIARTTTLGKDVSQITASI 741
Query: 3912 KKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXX 3733
+K + + ++ ++ + L+ T I++Q + L W+ L
Sbjct: 742 QKHKALEAECNSHRAICADVMRRGWDLSQKNPTHEE-NIQKQRDKLQTLWQQLQDEVANR 800
Query: 3732 XXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAAL 3553
+L +A ++++ D+DE W+QE+ + S+D+G+D S +AL +H +E+++AA
Sbjct: 801 KNRLQAAALIKQYFADIDEANSWLQERQTLVASKDYGKDESSAEALLHRHLRLEKEIAAY 860
Query: 3552 GDKIKSLDEKANRLRQSHPEAA-------------------------------------- 3487
+++ L E+A + P A
Sbjct: 861 STEMRRLKEQAAIAAEQAPAAMVKTEAPDDLNQKTAKLPFSRTWATSESALPGSSSLDIH 920
Query: 3486 ---EQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSS 3316
E I+ Q E++ + L S A +RK+ L + +Y RF S W+ + +
Sbjct: 921 FVPENIWKTQDEIDSLYENLQSMAEDRKKALEEMIEYYRFCSSCEAFQSWMREKENIFRT 980
Query: 3315 QELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVN 3136
+ D E + +++Q + TE+ + + + + +I+ L+ ++
Sbjct: 981 LQPQAD--NVEVMQQKYQSFLTELAAGKGQLGEIESLATKFGKNSPGKYTEIQIWLKEIH 1038
Query: 3135 EARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDPSGD--NVESLI 2962
+ +E + + L +++ F DC+ + + L +P +ES
Sbjct: 1039 ARWQHMESLKEEKGSELIGVADVRTFLEDCQSIGVLLQDKMGQLRNLEPGNSPAGLESDK 1098
Query: 2961 KKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKR 2782
+K ++ I E KI+ L+ A+S+ N +S A+T + + + LK +KR
Sbjct: 1099 RKLSVVEREILVIERKIEYLRSVAKSIKDTNPAESKAITVQVENMESLLVNLKLETQRKR 1158
Query: 2781 FKLGESQTLQQFSRDADEIENWMTE-KFQIAQEENYRDPTNIQQKHQKQQAFEAELHANS 2605
L ++Q Q F +D+ + W + ++ EE D + + ++ Q E+ +
Sbjct: 1159 DLLQQAQNQQSFLQDSRRLLLWAEGIREKLRSEEMGVDVASAEHLLREHQDLLKEIRSQK 1218
Query: 2604 DRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSF 2425
+R + + G +I+ V ++ L ++ L ++ +L++ + + F
Sbjct: 1219 ERFLQLEELGRKIIQKQPSNSRTRDVHLSVERLAEENKELENMWEQRWKKLQDGLELQKF 1278
Query: 2424 MAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADS 2245
+ L E L+ +D G + +V +L K+H E ++ + R+ NE
Sbjct: 1279 NREGDRINAALSSHEAFLRGDDLGDHVDAVRSLQKQHQEFEQLLMVLKRRIEAFNENGAD 1338
Query: 2244 LLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEK 2065
L+E+ F I ER + R++ + + + R+ +L +L + +F RD + W++EK
Sbjct: 1339 LIESGHFASHAIKERMATLRQRWERLVENNSKRKQRLLDSLQLQEFNRDAAELLIWMEEK 1398
Query: 2064 KLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQ 1885
+ S + Y RD V + H + E+ ++E + KG +L++ A
Sbjct: 1399 YKIASDESY-RDPTNVLRKLKWHEAAEKEMMANEKHFITLIKKGNQLIQDDHYAAAS--- 1454
Query: 1884 IKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGE 1705
I+K+M +LE+ W ++ R +L ++ + + +++ + + + +++L G
Sbjct: 1455 IQKKMSELEKKWKELYGKMIERGDKLRQAGQQEQLMELLQDAKKKIEKIEKVLQEAETGH 1514
Query: 1704 NMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIE 1525
++ + LLK+H + + +++ +++ + N + + I + R
Sbjct: 1515 DLRSSRDLLKQHRQLENETHELAEKMNSIVSHAMKMATN-HFDSQRILDETQKYLKRFES 1573
Query: 1524 IESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQILLTKQEA 1345
+++ + R L +F D+ +WI E+ S + G+ L Q LL K +
Sbjct: 1574 LQAPLDERRKLLEAAVDLYEFYHYHDMELNWINERLPIASSTNCGKSLDVAQSLLQKHKE 1633
Query: 1344 FDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEAR 1180
F A +NA + + +QR+ + ++ ++H + I ++ ++ WQ L E R
Sbjct: 1634 FQAEVNAHKQQ-VQRVLDKGRTMIVNQHPSAQKINEKCQELVTAWQGLEKACEER 1687
Score = 211 bits (538), Expect = 2e-52
Identities = 134/498 (26%), Positives = 240/498 (47%), Gaps = 9/498 (1%)
Frame = -1
Query: 7203 TADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEE 7024
+A I+++ QE++ + + + + +L+ + FQ F + +L WI EK +
Sbjct: 1662 SAQKINEKCQELVTAWQGLEKACEERTKQLQHSVGFQEFLMNTSDLEAWIAEKRPLVMSK 1721
Query: 7023 NF-RDPSNLQAKIQKHEAFEAEVQAHA-------KTIANLDKTGNAMIQHNHFASEHIKK 6868
++ +D +QKH+ E E+ + +++ NL G+ E +
Sbjct: 1722 DYGKDEDGTLKLLQKHKVLEHEIAVYQDLIKELNESVQNLPAMGSIQYVEVDAPREQVHS 1781
Query: 6867 RLEELHALWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLE 6688
RL EL L +G KL + L L F+R+ +++ W+ +++ ++ED G + E
Sbjct: 1782 RLRELQEL-------AATRGKKLDETLVLHEFLREYEDLQDWMAQQKQAASSEDYGNNYE 1834
Query: 6687 HVEILQRKFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNT 6508
HV L+ K+D F +L R+ Q A+ L+ GHSE +I +K+ D+ ++W L
Sbjct: 1835 HVLQLRAKYDTFRHQLEATGKRVMTCQQLAENLLNAGHSESREIRQKQKDLRNSWEELLE 1894
Query: 6507 LAATRKEGLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTER 6328
+ R E L A + + +D + LA I EK ++ DD +D+ VQ R H E
Sbjct: 1895 ITRLRGERLKDAEVIHKCYQDLTDALAHIEEKSKSIP-DDVAKDMRGVQTQLRNHVALEH 1953
Query: 6327 DLAALEGKMLQLEKEA-HKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSF 6151
+L E ++ L A H L ++A + K W ALK K Q RK+ LE++
Sbjct: 1954 ELLGNEQQLQDLIHSADHVLTRCSNEQASGLKAKQQAIVTNWKALKSKVQLRKELLEQAH 2013
Query: 6150 QLHRFLADYRDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTA 5971
+L++F A D SW +M + A E +D++ + L HQ+ EI+A+ + +NQ
Sbjct: 2014 KLYQFQAQVWDYFSWTSEMIREMRAKETIRDISTSSLRLTQHQQLLAEIEAQEEKYNQIV 2073
Query: 5970 SAGQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAET 5791
GQ L++ S E+++KL+ L EK + W++++ ++ Q+FY+D +
Sbjct: 2074 QLGQSLLQDEEIRSKEIRQKLQALLEEKDKVYSEWQQKKKWLDRIHQEQMFYKDWNHLDK 2133
Query: 5790 WMNKQEAFLANTDLGDSL 5737
+N QE L T + ++
Sbjct: 2134 LLNSQEEMLVFTSVSKAV 2151
Score = 93.2 bits (230), Expect = 8e-17
Identities = 61/283 (21%), Positives = 126/283 (43%), Gaps = 1/283 (0%)
Frame = -1
Query: 7197 DDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEENF 7018
D I +R +++ + QT+ + L A+Q + D DE+ W+ EK +++
Sbjct: 3706 DIIQKRTKQINEMWEKLCHAIQTRTENLRAAQQVHQYDHDVDEVKGWMQEKEAVVDIDDY 3765
Query: 7017 R-DPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALW 6841
D +Q + + E E ++ A K + + + + E+I +RL ++ W
Sbjct: 3766 GYDLPGVQTLLSQLEGVERDLGAIMKELERIRGEAWHLSRTYPQLKENIMERLTDVDECW 3825
Query: 6840 XXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKF 6661
+ +L QA ++ + C E++ W E V +E++ D+ E+L ++
Sbjct: 3826 RNLDKKFLERKARLSQAEQVQLYFNDCRELMAWANEMHALVISEELANDVLGAELLIKRH 3885
Query: 6660 DDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGL 6481
D++ +E+ + EI +A D L GH +I +K ++++ ++ RKE
Sbjct: 3886 DEYKREIEKQWLKYEEIQRAGDDLTRNGHFMSVEIEEKLLELSELMKKVKESWNVRKELY 3945
Query: 6480 FGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQ 6352
++Q R+ ++ AW+ K+ LS YG ++ L+
Sbjct: 3946 EENWEIQLLRRELEQAEAWLAAKESFLSDPSYGVSKDSTTVLK 3988
Score = 88.2 bits (217), Expect = 3e-15
Identities = 111/587 (18%), Positives = 233/587 (38%), Gaps = 51/587 (8%)
Frame = -1
Query: 2112 QFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKG 1933
+F + E+++++ + ++ D+ + V + ++++ +A P+
Sbjct: 493 RFLKKAALRETYLEDMRKVIGKQDFWPE--SVDRMEAASKKLEAIVADVLPRRERFASLA 550
Query: 1932 EELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEA 1753
E + +DQI K+ + + W + D R L + A L D++
Sbjct: 551 EMATVISQNNYHSKDQIVKKENSISKQWQDLLDQLQKRQHSLSTMQEILALLRDIDAIME 610
Query: 1752 WMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHA 1573
+ E Q ++ S + G+ + V LL+KH+ + + + ++ + + + + A
Sbjct: 611 ELKELQALVNSQDCGKQLLEVVDLLQKHNLIDLQISSYDDKLTHITQRTAEISKDSTVKA 670
Query: 1572 PHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDF 1393
+ + LR + + + R ++L + +F C E+WI+EK + R+
Sbjct: 671 EVLYAKVPMLRQLYQNLIAQSRTRKSQLEEALKLFEFFRDCKEEEAWISEKWKIARTTTL 730
Query: 1392 GRDLSSVQILLTKQEAFDAGLNAFE--------------------HEGIQRITE------ 1291
G+D+S + + K +A +A N+ E IQ+ +
Sbjct: 731 GKDVSQITASIQKHKALEAECNSHRAICADVMRRGWDLSQKNPTHEENIQKQRDKLQTLW 790
Query: 1290 --LKDQLVSSEHQ-QSPAIEKRH-------TNVIQRWQNLLAHSEARRXXXXXXXXXXXQ 1141
L+D++ + +++ Q+ A+ K++ + +Q Q L+A + +
Sbjct: 791 QQLQDEVANRKNRLQAAALIKQYFADIDEANSWLQERQTLVASKDYGKDESSAEA----- 845
Query: 1140 IEELYLAFAKKASTFNSWFEN--------AEEDLTDPVRCNSLEEIRALRDAHGEFQRSL 985
+ +L K+ + +++ AE+ V+ + +++ + A F R+
Sbjct: 846 LLHRHLRLEKEIAAYSTEMRRLKEQAAIAAEQAPAAMVKTEAPDDLNQ-KTAKLPFSRTW 904
Query: 984 SSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQ 805
+++E LD N+ W T D ++ + NLQ + ++R++ L
Sbjct: 905 ATSESALPGSSSLDIHFVPENI------WKTQDEIDSLYENLQSMAEDRKKAL------- 951
Query: 804 EENDKLRREFAKLANAFHAWLTNTRQEMMEAGGTLEEQLDAVERKAK-------EIKANK 646
EE + R F AF +W+ +E TL+ Q D VE + E+ A K
Sbjct: 952 EEMIEYYR-FCSSCEAFQSWM----REKENIFRTLQPQADNVEVMQQKYQSFLTELAAGK 1006
Query: 645 GQLRQIEEKGAMLERNLILDNRYTEHSTVGIAQAWDQLDQLAMRMQH 505
GQL +IE +N +YTE Q W L ++ R QH
Sbjct: 1007 GQLGEIESLATKFGKN--SPGKYTE------IQIW--LKEIHARWQH 1043
>gi|25155104|ref|NP_741632.1| SMAll body size SMA-1, betaH chain
spectrin homolog required for embryonic elongation and
morphogenesis; expressed in epithelial cells (470.0 kD)
(sma-1) [Caenorhabditis elegans]
gi|11359811|pir||T42993 probable spectrin beta chain - Caenorhabditis
elegans
gi|2997690|gb|AAC08577.1| beta chain spectrin homolog Sma1
[Caenorhabditis elegans]
gi|14530518|emb|CAB04608.2| C. elegans SMA-1 protein (corresponding
sequence R31.1) [Caenorhabditis elegans]
gi|14530529|emb|CAB00130.2| Hypothetical protein R31.1
[Caenorhabditis elegans]
Length = 4063
Score = 652 bits (1681), Expect = 0.0
Identities = 548/2272 (24%), Positives = 1003/2272 (44%), Gaps = 74/2272 (3%)
Frame = -1
Query: 6801 LQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELG-NHQY 6625
L +KLL F R+CDE W +E E + E EHV +RKFD ++ N
Sbjct: 931 LSDNIKLLRFYRECDEFERWAKEIEVSLADEPSP---EHVAAFRRKFDKLEADMKTNGGT 987
Query: 6624 RINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRD 6445
++ IN A+ L+ EGH + +I ++ +N W L L R L +V F+
Sbjct: 988 QLKHINDIANDLISEGHGQSRKIEVRQHKINAMWDNLERLRKQRGVRLEATERVADFDTT 1047
Query: 6444 ADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAE 6265
+ W+ K + R+ N+V++LQ ERDL LE K+ LEK A + +
Sbjct: 1048 CESAREWMLSK-----FEQLDRNPNDVKSLQN----LERDLKPLEDKIAALEKLAAAVKK 1098
Query: 6264 THPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAV 6085
HP+ A AI +K + +A L +AQ + E++ F + RD+I WI + V
Sbjct: 1099 DHPEEAAAIERKIAELRALHADLLRRAQEKMLLAEQTQGKEMFESALRDMIGWIEKTRKV 1158
Query: 6084 IGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLE 5905
+ D DVA AE LL+ H E +I + G++L+E P +V+E+L+
Sbjct: 1159 MMEDVHPVDVAEAEELLKKHYELGEQIKDKKYEVEYCQELGRRLLERN-PRMSKVEEQLQ 1217
Query: 5904 KLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSVE 5725
L E +SL L+ R + +Q +DLQLF R++E+ + EAFL +LGDS++SVE
Sbjct: 1218 NLVSEMASLRDLYRRRDTILKQQLDLQLFNRESERIDAATKGHEAFLEFDNLGDSVESVE 1277
Query: 5724 HLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXXX 5545
+L+K+H D E L AQE ++ A A +I+ QH + + +
Sbjct: 1278 NLLKRHRDLEAKLDAQEARLEAFSRTADDMIKAQHADSAYIEQRRRDVLARREAVRRAAA 1337
Query: 5544 XRGNALKESYKRQTFDRDCDEMVSWITEK--LSTARDDSYLDPTNIRGKLQKHINFEQEL 5371
R L+ S + Q R+ DE+V W+ EK L + DDS L P+ I +L KH FE E+
Sbjct: 1338 QRKKQLEASLEYQEMRREADEVVGWMYEKAKLVMSGDDSALAPSAIPHRLLKHEAFEAEI 1397
Query: 5370 KANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQ 5191
ANE R+ I S G+ ++ H+ + ++ +RQVN W +L KG +LR+A +++
Sbjct: 1398 IANEPRIQQINSEGDGLVSKKHYESPNVEKIVRQVNAQWGDLKKQVWNKGLRLRQAADQK 1457
Query: 5190 QFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLA 5011
+R +ED A L E++ + S+D G DL SV++L +K ++E + + +++ I+
Sbjct: 1458 GLDRILEDAHAKLDEMQTALNSKDQGLDLRSVKDLLQKHAVLEQEMGLYGNKLSDIENRG 1517
Query: 5010 QQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIR 4831
++ + H++A I L QRY A++ P ++RK L ES +QL D++ EL WI
Sbjct: 1518 KKMAVDGHYDADRIHSTVGQLLQRYAAMKGPAQRRKGDLDESRLWHQLVFDVDCELQWIA 1577
Query: 4830 EKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEI 4651
EK+ +A S + GR L N++KKQ+ L AE+ H QI+ V A ++I++ H + +I
Sbjct: 1578 EKKPIASSQDCGRTLTEALNMVKKQEQLEAEVNQHGGQIDKVLLQAGELIKRHHSASSQI 1637
Query: 4650 RDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKD 4471
+ K ++L W LK RR +D ++ QYL DA E ++WM+EK + S DYG D
Sbjct: 1638 KAKSSELETAWSELKKLLRLRRAVVDWGVKEQQYLFDAAEVESWMNEKRNALASEDYGND 1697
Query: 4470 EDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQP------------------M 4345
ED+A LL KHRAL D+ ++ +E L + + +P +
Sbjct: 1698 EDAARKLLSKHRALCEDMTTYRQWLEKLEVKCVELVESNRPHVERFQKRQDELVREFDAL 1757
Query: 4344 GQLGRD------CVLALYDY-QEKSPREVSMKKGDVLTLLNASNRDWWKV-EVNDRQGFV 4189
+L D + LY+Y +E + S+++ + + D+ + E+ +
Sbjct: 1758 SKLAEDRRNALEDAVCLYEYMRESADLGQSIEENLRVAMSEEFAEDYEHLKELQSKFDEF 1817
Query: 4188 PAAYVKRIEPGTAQQHAQQQV--------NSIGGKQSEIEDKYQRLMMLGETRKRKLEEA 4033
E T+ + A + + KQ + + L E R KL A
Sbjct: 1818 KQKVKNGSERFTSCETAANAILRRNPPFARDVVKKQEALRTAWNTLCEYIEARDSKLAVA 1877
Query: 4032 CKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKKFDDFKGDLKANEVRLQEM 3853
+ ++ R+ ++ +W+ + A +++G D++ V L + + ++ ++ RL ++
Sbjct: 1878 EELHRFHRDVDEFEQWMADKMA-NMPRDLGRDVKHVHSLWQHHEALDKEIHNSQPRLAKL 1936
Query: 3852 NQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHRDVDET 3673
+ A L A +I + + L W L L +A ++ F+ V +
Sbjct: 1937 VEEAERLKKTYPGGNAEQIGGRQQTLEQEWEELKNATDDRKDMLRAAFDLHTFNGKVRDL 1996
Query: 3672 RDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPE 3493
W + S+ DL+ + LQ +H + ++ A + L ++ +
Sbjct: 1997 LAWTDLTISDIQSDLHINDLQQAEWLQTEHSRLSHEMDAREPEFARLVNDGEKMITAQHY 2056
Query: 3492 AAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQ 3313
A+E+I + L RL S+ R L + + F + + ++ I S + S
Sbjct: 2057 ASEEIKNKTHLLKSALERLRSEWALRNGFLSQAVQWHAFQREAKQIIASIGSKRTTLRSL 2116
Query: 3312 ELANDVTGAEALLERHQEYR---TEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQG 3142
+ V E+ +R + + +D R AT D N+L+ + H + +I
Sbjct: 2117 AVGGSVADVESQTKRLDTFEKALSTLDERTAT---LDHTANELMKARHMESKNISMWQSN 2173
Query: 3141 VNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMS------AREAFLAQEDPSGD 2980
V+E K L AR +L L F D Q + W+ + L+ E S D
Sbjct: 2174 VHEELKLLRQDIEARHAMLKDAFALASFDSDVAQIEAWIDEKTNGVRKAQDLSSESISID 2233
Query: 2979 NVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRWNGLKE 2800
++ H+ + + + + + L + +KN H +P + + D++ +WN L
Sbjct: 2234 EKMKRLQTHQALEAEVTANKPVVDQI-LQRGNQLKNLH-RNPKIANRCDELSYKWNQLSG 2291
Query: 2799 ALIQKRFKLGESQTLQQFSRDADEIENWMTEK-FQIAQEENYRDPTNIQQKHQKQQAFEA 2623
A + L E++ L +F + + + W+ EK ++ + +D + + ++ +
Sbjct: 2292 ACADQSLALEEARDLLRFKQLVENVLAWINEKEVLVSTADMGKDMEHCRLLLERLDGTRS 2351
Query: 2622 ELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSYRLKEA 2443
+ + + I + G L++ + + V + LN++W LL+ L A
Sbjct: 2352 DSIVDEQTLDEINRLGEKLVKQGRSSRDQ--VQKEQQHLNEKWRLLLGQLAHYRTELLAA 2409
Query: 2442 NKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQDRVGEM 2263
+ +F V+D + + E ++S+DYGKD ASVE L++K S LE D+ A ++
Sbjct: 2410 MEVHTFNRDVEDTDERIHEKVAAMKSDDYGKDFASVELLVRKQSALERDMSAIHQKLIAH 2469
Query: 2262 NEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEE 2083
++ A +LE + + + K + + ++ + K A R +KL+++ ++++ D+ E
Sbjct: 2470 DKDAQKILEKRPPLRETVLDSLKKLEESWEQLSKAAELRNEKLNRSFKLYKYLDDVKKVE 2529
Query: 2082 SWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEA 1903
W + + ++S +D G + + +H E+ ++ L+ +G+ L + E
Sbjct: 2530 QWANQVRNKMTSHQTPKDSNGARKILEQHHERKAEIDGRSEELRLLHEEGQALNQEQPEH 2589
Query: 1902 GVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILG 1723
+ KR+++ E Q+R + L + + + + + E W+++K+ +
Sbjct: 2590 KAEVQRAHKRVQNSEH---QLRQTWESEKGTLQKLLEWMLWCDEAVQCEQWLSDKETQVA 2646
Query: 1722 SDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQL 1543
G+ V+ L+K H F+ + +++ L D L+ GN++ I R +++
Sbjct: 2647 RGELGDTTDAVEMLIKGHSAFEETVRKQSEKIDALTKNADALVSGGNNYRADIVTRSEEV 2706
Query: 1542 RARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDLSSVQIL 1363
AR + E R L D+ Y +F+ +C + WI K Q E F D ++++
Sbjct: 2707 TARHALLLKSMEKRGHMLEDSKKYHEFIRQCGELIIWITAKLQLAYDESF-LDHTNLRSK 2765
Query: 1362 LTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEA 1183
L K AFD+ L E + + + +QLV+ H S ++ + + W L S
Sbjct: 2766 LQKHMAFDSELVENE-KRLSTVERQGEQLVTDNHFMSEQVKAQLVELRSGWDELRTKSAL 2824
Query: 1182 RRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHG 1003
+ EL+ + +K W + E +L+ D HG
Sbjct: 2825 KTQRLREAF-------ELH-SLQRKVEDIEKWLDKVEGELSS--------------DDHG 2862
Query: 1002 EFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRI--------- 850
R + S E ++L L I DA+ + + + +
Sbjct: 2863 ---RDILSTELLIKKLDTLQTEIAG-----------RSDAVVEMMKKARELRVQGSAAAD 2908
Query: 849 --IKEREQELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEMM------------EA 712
+K+ EQ AR + +E ++RRE A AF W+ +++ E+
Sbjct: 2909 DCLKQAEQVEAR-YSGLDEPVQIRRENLVDAQAFFQWVKAAEEDLEWLSDRMMLASSGES 2967
Query: 711 GGTLEEQLDAVERKA---KEIKANKGQLRQIEEKGAMLERNLILDNRYTEHSTVGIAQAW 541
G +L+ L ++ A KE+ + + E++G + R + + + ++ A
Sbjct: 2968 GDSLQSALSLQKKHATLEKELDTRQSAMNDTEQRGKDMIRQRHFASTHIQKILDRLSSAM 3027
Query: 540 DQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMMFKHFDKEKTGRLDHQQFKSCLRA 361
L + + L++ I A EA + ++ GR D +S LR
Sbjct: 3028 LTLKESCGLRRDLLQEAIDAHEYYTEETEAEQWLREQMPLAMSQEMGR-DQAGAESHLRR 3086
Query: 360 LGYDLPMVDEGQPEPE-FQRILDIVDPNRDGYVTLQEYMAFMISKETENIQS 208
L ++D+ E E F+ +D + DG + + + A I+ + +++
Sbjct: 3087 ----LTVLDK---EVELFKNEIDRLKKRADGLLAREHHDAMSIAAKQRKLEA 3131
Score = 558 bits (1439), Expect = e-157
Identities = 362/1353 (26%), Positives = 660/1353 (48%), Gaps = 46/1353 (3%)
Frame = -1
Query: 7152 IFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEK---LQTAQEENFRDPS--NLQAKI 6988
+ + + + L++A F D ++ WI EK ++ AQ+ + S ++
Sbjct: 2180 LLRQDIEARHAMLKDAFALASFDSDVAQIEAWIDEKTNGVRKAQDLSSESISIDEKMKRL 2239
Query: 6987 QKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKG 6808
Q H+A EAEV A+ + + + GN + N + I R +EL W +
Sbjct: 2240 QTHQALEAEVTANKPVVDQILQRGNQL--KNLHRNPKIANRCDELSYKWNQLSGACADQS 2297
Query: 6807 IKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQ 6628
+ L++A LL F + + +L WI EKE V+ DMG D+EH +L + D + +
Sbjct: 2298 LALEEARDLLRFKQLVENVLAWINEKEVLVSTADMGKDMEHCRLLLERLDGTRSDSIVDE 2357
Query: 6627 YRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNR 6448
++EIN+ +KLV++G S DQ+ K++ +N+ W L A + L A +V FNR
Sbjct: 2358 QTLDEINRLGEKLVKQGRSSRDQVQKEQQHLNEKWRLLLGQLAHYRTELLAAMEVHTFNR 2417
Query: 6447 DADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLA 6268
D ++T I EK A+ SDDYG+D +V+ L RK ERD++A+ K++ +K+A K+
Sbjct: 2418 DVEDTDERIHEKVAAMKSDDYGKDFASVELLVRKQSALERDMSAIHQKLIAHDKDAQKIL 2477
Query: 6267 ETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKA 6088
E P E + + +W L + A+ R + L RSF+L+++L D + + W ++
Sbjct: 2478 EKRPPLRETVLDSLKKLEESWEQLSKAAELRNEKLNRSFKLYKYLDDVKKVEQWANQVRN 2537
Query: 6087 VIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKL 5908
+ + + KD GA +LE H E K EID R++ GQ L + EVQ
Sbjct: 2538 KMTSHQTPKDSNGARKILEQHHERKAEIDGRSEELRLLHEEGQALNQEQPEHKAEVQRAH 2597
Query: 5907 EKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDSLDSV 5728
+++ + + L WE + ++ ++ L+ + Q E W++ +E +A +LGD+ D+V
Sbjct: 2598 KRVQNSEHQLRQTWESEKGTLQKLLEWMLWCDEAVQCEQWLSDKETQVARGELGDTTDAV 2657
Query: 5727 EHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXXXXXX 5548
E LIK H FE+++ Q EKI+AL + A L+ G + D+
Sbjct: 2658 EMLIKGHSAFEETVRKQSEKIDALTKNADALVSGGNNYRADIVTRSEEVTARHALLLKSM 2717
Query: 5547 XXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQELK 5368
RG+ L++S K F R C E++ WIT KL A D+S+LD TN+R KLQKH+ F+ EL
Sbjct: 2718 EKRGHMLEDSKKYHEFIRQCGELIIWITAKLQLAYDESFLDHTNLRSKLQKHMAFDSELV 2777
Query: 5367 ANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQ 5188
NE RL + GEQ++ HF ++ + +L ++ + W+EL + K +LREA
Sbjct: 2778 ENEKRLSTVERQGEQLVTDNHFMSEQVKAQLVELRSGWDELRTKSALKTQRLREAFELHS 2837
Query: 5187 FNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQ 5008
R +ED+E WL ++EG+++S+D+G+D++S + L KK+ ++++ +D V + + A+
Sbjct: 2838 LQRKVEDIEKWLDKVEGELSSDDHGRDILSTELLIKKLDTLQTEIAGRSDAVVEMMKKAR 2897
Query: 5007 QFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIRE 4828
+ + + A +++ E ++ RY+ L +P++ R+ L ++ Q + E++L W+ +
Sbjct: 2898 ELRVQGSAAADDCLKQAEQVEARYSGLDEPVQIRRENLVDAQAFFQWVKAAEEDLEWLSD 2957
Query: 4827 KEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIR 4648
+ +A S G L +L KK L E+ S + DMI+Q HF + I+
Sbjct: 2958 RMMLASSGESGDSLQSALSLQKKHATLEKELDTRQSAMNDTEQRGKDMIRQRHFASTHIQ 3017
Query: 4647 DKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDE 4468
L +L LK RR L +++ AH+Y ++ EA+ W+ E+ P+ S + G+D+
Sbjct: 3018 KILDRLSSAMLTLKESCGLRRDLLQEAIDAHEYYTEETEAEQWLREQMPLAMSQEMGRDQ 3077
Query: 4467 DSAEALLKKHRALLSDLEAFKGTIEDLRKQ---------------ASQCKYQEQPMGQLG 4333
AE+ L++ L ++E FK I+ L+K+ A++ + E G L
Sbjct: 3078 AGAESHLRRLTVLDKEVELFKNEIDRLKKRADGLLAREHHDAMSIAAKQRKLEALFGDLC 3137
Query: 4332 RDCVLALYDYQEKSPREVSMKKGDVLT------LLNASNRDWWKVEVNDRQGFVP--AAY 4177
R+C + S +++ D L+ +AS D+ + ++ D Q + +
Sbjct: 3138 RECARRRTQIVDASKYHKFVRQADDLSDWLREKERSASAEDYGQ-DLEDCQQIIEQFEST 3196
Query: 4176 VKRI----EPGTAQQHAQQQV--------NSIGGKQSEIEDKYQRLMMLGETRKRKLEEA 4033
V+ + E A Q AQ+ + SI K ++++ + + + RK+ L A
Sbjct: 3197 VRELAAAGERVAAVQRAQEDLLRSGHPYGASITAKGADVQRLWTHVNEVANERKQALNGA 3256
Query: 4032 CKGYQLLREANDLAEWIKSREA--VAAQQE--IGTDLEQVEVLQKKFDDFKGDLKANEVR 3865
+ ++ +EA+ + W++ +EA VA +QE DL V+ ++ D+F +KA E +
Sbjct: 3257 RQVHRFDQEADQILNWLQDKEATGVAMEQEDLSRADLASVKAQLQRHDEFMHGMKAVEKQ 3316
Query: 3864 LQEMNQIATAL-TSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAHEVQRFHR 3688
+ E+ A L S T + +R+ D+ + + + +L +Q + +
Sbjct: 3317 VAELCHEAERLWNSFPDTRHHLEVRRL--DMEEQLKDILEAAKKHLEKLRHMQSLQSYFQ 3374
Query: 3687 DVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLDEKANRLR 3508
+ E W++ + SE RD+ S ++L R+H+ ++ + + R+
Sbjct: 3375 EYREMMQWMKNMQSTMTSEQLPRDVASCESLVRRHDEYNLEMQGRKPFVDDFARQGRRMI 3434
Query: 3507 QSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQ 3328
QS +++I + L + W L +R E ++ D Q++ + L W+
Sbjct: 3435 QSSHVLSQEIQEKVDILEKSWAMLCEIWKDRAELYEENMDVQKWKQNAEQLDSWLEERAG 3494
Query: 3327 LVSSQ-ELANDVTGAEALLERHQEYRTEIDSRA 3232
L+ + + V AE L ++ +++++
Sbjct: 3495 LLGDDWRMVDSVEMAETHLRDFDDFLVTLEAQS 3527
Score = 558 bits (1438), Expect = e-157
Identities = 420/1600 (26%), Positives = 731/1600 (45%), Gaps = 35/1600 (2%)
Frame = -1
Query: 5478 VSWITEKLSTARDDSYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFA 5299
V + E++ R S ++ T L+K ++ A E+R + + ++ +
Sbjct: 439 VQVVLEEMEHGRSASQVEKT-----LKKQQAISTDILAREDRFKMLTAMCNELCTEKYHE 493
Query: 5298 ADHIGDRLRQVNNLWNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASED 5119
+D + R++ + W +L+ ++ L + R+I+ + L LE V + D
Sbjct: 494 SDKVRGMEREIIDRWTQLLTLLEQRKRALMSLNDLMSLLRDIDTLSNELYSLEPAVRNRD 553
Query: 5118 YGKDLVSVQNLQKKIGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQR 4939
GK L+ V++L K L+++ NAH + + Q A + + V+ RK + + +
Sbjct: 554 VGKHLIGVEDLLGKHDLLDAQINAHGSLLSKLSQSANNYIRHKEEQFDVLQRKLDEVTAQ 613
Query: 4938 YNALRDPLEKRKRKLGESHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKK 4759
YN L + R+ L + Q +D E+E+AW+ EKE++ + D+ V
Sbjct: 614 YNTLVELCRSRRLGLERARSLFQFVQDHEEEMAWLAEKEKLCTTALNSGDISAVPQTTLL 673
Query: 4758 QQALIAEIANHDSQIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTD 4579
+ + E+ H ++ + + + ++Q G +I+ +L Q+ W L+ +
Sbjct: 674 YKNVEMEMQTHWARSKGMIAGGERLVQNGQ-SKEDIQRRLTQMNHRWERLRVAVDALGNW 732
Query: 4578 LDDSLQAHQYLSDANEADAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGT 4399
L ++ A QY DANEA++W+ EK P+V S D G+DE +AE+LL++H L ++ A+K
Sbjct: 733 LSEARHAQQYFQDANEAESWIREKMPLVKSDDLGRDEGAAESLLQRHARLEEEIRAYKSD 792
Query: 4398 IEDLRKQASQ----------CKYQEQPMGQLGRDCVLALYDYQEKSPREVSMKKGDVLTL 4249
I L + SQ Q ++ V Y+Y+ R + KG+VL L
Sbjct: 793 ISRLEEMQSQLANSAFHTATTSQSVQETEEVNVPQVEMSYNYEGNGMR---VSKGEVLAL 849
Query: 4248 LNASNRDWWKVEVND-RQGFVPAAYVKRIEPG---TAQQHAQQQVNSIGG---------- 4111
L S +WW+ D +G+VPA Y K I PG T Q Q+ ++ G
Sbjct: 850 LEKSTPEWWRALKRDGTEGYVPANYCK-IVPGETVTVTQTTQKTTTTLEGNETKSSVVAD 908
Query: 4110 KQSEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLE 3931
+Q +I + Y+ L L + R+R L + K + RE ++ W K E A + E
Sbjct: 909 RQHKISNDYRELKRLADVRRRLLSDNIKLLRFYRECDEFERWAKEIEVSLADE---PSPE 965
Query: 3930 QVEVLQKKFDDFKGDLKAN-EVRLQEMNQIATALTSVGQTET-AVRIRQQIEDLNARWRA 3757
V ++KFD + D+K N +L+ +N IA L S G ++ + +RQ +NA W
Sbjct: 966 HVAAFRRKFDKLEADMKTNGGTQLKHINDIANDLISEGHGQSRKIEVRQ--HKINAMWDN 1023
Query: 3756 LXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEG 3577
L +L + V F + R+W+ K + LD R+ V++LQ
Sbjct: 1024 LERLRKQRGVRLEATERVADFDTTCESAREWMLSKFEQLD-----RNPNDVKSLQ----N 1074
Query: 3576 VERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLD 3397
+ERDL L DKI +L++ A +++ HPE A I EL L +A +
Sbjct: 1075 LERDLKPLEDKIAALEKLAAAVKKDHPEEAAAIERKIAELRALHADLLRRAQEKMLLAEQ 1134
Query: 3396 SYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQA 3217
+ + F S RD++ WI +++ DV AE LL++H E +I + +
Sbjct: 1135 TQGKEMFESALRDMIGWIEKTRKVMMEDVHPVDVAEAEELLKKHYELGEQIKDKKYEVEY 1194
Query: 3216 FDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQA 3037
+ G +LL + +E +LQ + L D + R IL Q L+LQLF R+ E+
Sbjct: 1195 CQELGRRLL-ERNPRMSKVEEQLQNLVSEMASLRDLYRRRDTILKQQLDLQLFNRESERI 1253
Query: 3036 DTWMSAREAFLAQEDPSGDNVES---LIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNH 2866
D EAFL + D GD+VES L+K+H D + ++ QE +++ A+ +IK H
Sbjct: 1254 DAATKGHEAFL-EFDNLGDSVESVENLLKRHRDLEAKLDAQEARLEAFSRTADDMIKAQH 1312
Query: 2865 YDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQ- 2689
DS + ++R +L R ++ A Q++ +L S Q+ R+ADE+ WM EK ++
Sbjct: 1313 ADSAYIEQRRRDVLARREAVRRAAAQRKKQLEASLEYQEMRREADEVVGWMYEKAKLVMS 1372
Query: 2688 -EENYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLK 2512
+++ P+ I + K +AFEAE+ AN RI I G+ L+ +K V ++
Sbjct: 1373 GDDSALAPSAIPHRLLKHEAFEAEIIANEPRIQQINSEGDGLV--SKKHYESPNVEKIVR 1430
Query: 2511 ALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVE 2332
+N QW L K K RL++A QK ++D L E++ L S+D G DL SV+
Sbjct: 1431 QVNAQWGDLKKQVWNKGLRLRQAADQKGLDRILEDAHAKLDEMQTALNSKDQGLDLRSVK 1490
Query: 2331 NLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMAT 2152
+LL+KH++LE ++ + +++ ++ + + + + +I + RY +K A
Sbjct: 1491 DLLQKHAVLEQEMGLYGNKLSDIENRGKKMAVDGHYDADRIHSTVGQLLQRYAAMKGPAQ 1550
Query: 2151 DRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELA 1972
R+ L ++ HQ D+D E WI EKK + SS D GR L N+ +K +++ E+
Sbjct: 1551 RRKGDLDESRLWHQLVFDVDCELQWIAEKKPIASSQDCGRTLTEALNMVKKQEQLEAEVN 1610
Query: 1971 SHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEA 1792
H Q+ V L+ EL++ A QIK + +LE +W +++ L R +D
Sbjct: 1611 QHGGQIDKVLLQAGELIKRHHSA---SSQIKAKSSELETAWSELKKLLRLRRAVVDWGVK 1667
Query: 1791 FQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLIN 1612
Q +L D E E+WMNEK+ L S+++G + + LL KH D+ ++Q + L
Sbjct: 1668 EQQYLFDAAEVESWMNEKRNALASEDYGNDEDAARKLLSKHRALCEDMTTYRQWLEKLEV 1727
Query: 1611 KGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESW 1432
K L+ + H ++R D+L + +AE R L D ++M + +
Sbjct: 1728 KCVELVESNRPHVERFQKRQDELVREFDALSKLAEDRRNALEDAVCLYEYMRESADLGQS 1787
Query: 1431 IAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQS 1252
I E + SE+F D ++ L +K + F + G +R T + + +
Sbjct: 1788 IEENLRVAMSEEFAEDYEHLKELQSKFDEFKQKVK----NGSERFTSCETAANAILRRNP 1843
Query: 1251 P---AIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFE 1081
P + K+ + W L + EAR EEL+ F + F W
Sbjct: 1844 PFARDVVKKQEALRTAWNTLCEYIEAR-------DSKLAVAEELH-RFHRDVDEFEQWMA 1895
Query: 1080 NAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQL-QDLDRRIKSFNVGPNPY 904
+ ++ + ++ + +L H + + +++ +L ++ +R K++ G
Sbjct: 1896 DKMANMPRDLG-RDVKHVHSLWQHHEALDKEIHNSQPRLAKLVEEAERLKKTYPGGNAEQ 1954
Query: 903 TWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLR 784
LE W L+ +R+ L N K+R
Sbjct: 1955 IGGRQQTLEQEWEELKNATDDRKDMLRAAFDLHTFNGKVR 1994
Score = 492 bits (1267), Expect = e-137
Identities = 453/2332 (19%), Positives = 981/2332 (41%), Gaps = 69/2332 (2%)
Frame = -1
Query: 7191 IHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEK--LQTAQEENF 7018
I QRR++VL + + ++ +LE + ++Q +R+ADE+ W+ EK L + +++
Sbjct: 1318 IEQRRRDVLARREAVRRAAAQRKKQLEASLEYQEMRREADEVVGWMYEKAKLVMSGDDSA 1377
Query: 7017 RDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWX 6838
PS + ++ KHEAFEAE+ A+ I ++ G+ ++ H+ S +++K + +++A W
Sbjct: 1378 LAPSAIPHRLLKHEAFEAEIIANEPRIQQINSEGDGLVSKKHYESPNVEKIVRQVNAQWG 1437
Query: 6837 XXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRKFD 6658
KG++L+QA R ++ + E +T + ++D G+DL V+ L +K
Sbjct: 1438 DLKKQVWNKGLRLRQAADQKGLDRILEDAHAKLDEMQTALNSKDQGLDLRSVKDLLQKHA 1497
Query: 6657 DFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLF 6478
+E+G + ++++I K+ +GH + D+I+ + + + A RK L
Sbjct: 1498 VLEQEMGLYGNKLSDIENRGKKMAVDGHYDADRIHSTVGQLLQRYAAMKGPAQRRKGDLD 1557
Query: 6477 GAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKML 6298
+ + D D L WI EK SS D GR L + +K E E ++ G++
Sbjct: 1558 ESRLWHQLVFDVDCELQWIAEKKPIASSQDCGRTLTEALNMVKKQEQLEAEVNQHGGQID 1617
Query: 6297 QLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRD 6118
++ +A +L + H + I K+ + + AW+ LK+ + R+ ++ + ++L D +
Sbjct: 1618 KVLLQAGELIKRHHSASSQIKAKSSELETAWSELKKLLRLRRAVVDWGVKEQQYLFDAAE 1677
Query: 6117 LISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGI 5938
+ SW+ + + + +++ D A LL H+ ++ + +LVE
Sbjct: 1678 VESWMNEKRNALASEDYGNDEDAARKLLSKHRALCEDMTTYRQWLEKLEVKCVELVESNR 1737
Query: 5937 PESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQEAFLAN 5758
P Q++ ++L E +L L E+RR E + L + R++ + + +
Sbjct: 1738 PHVERFQKRQDELVREFDALSKLAEDRRNALEDAVCLYEYMRESADLGQSIEENLRVAMS 1797
Query: 5757 TDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXX 5578
+ + + ++ L K ++F++ + E+ + + A +++ A DV +
Sbjct: 1798 EEFAEDYEHLKELQSKFDEFKQKVKNGSERFTSCETAANAILRRNPPFARDVVKKQEALR 1857
Query: 5577 XXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGKLQ 5398
R + L + + F RD DE W+ +K++ D D ++ Q
Sbjct: 1858 TAWNTLCEYIEARDSKLAVAEELHRFHRDVDEFEQWMADKMANMPRDLGRDVKHVHSLWQ 1917
Query: 5397 KHINFEQELKANENRLDDIRSTGEQI---IDSGHFAADHIGDRLRQVNNLWNELVDATNK 5227
H ++E+ ++ RL + E++ G+ A+ IG R + + W EL +AT+
Sbjct: 1918 HHEALDKEIHNSQPRLAKLVEEAERLKKTYPGGN--AEQIGGRQQTLEQEWEELKNATDD 1975
Query: 5226 KGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNA 5047
+ LR A + FN + D+ AW + S+ + DL + LQ + + + +A
Sbjct: 1976 RKDMLRAAFDLHTFNGKVRDLLAWTDLTISDIQSDLHINDLQQAEWLQTEHSRLSHEMDA 2035
Query: 5046 HNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQL 4867
+ ++ +H+ + I K L+ LR R L ++ Q +
Sbjct: 2036 REPEFARLVNDGEKMITAQHYASEEIKNKTHLLKSALERLRSEWALRNGFLSQAVQWHAF 2095
Query: 4866 FRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAAND 4687
R+ + +A I K S G + V++ K+ ++ D + ++ AN+
Sbjct: 2096 QREAKQIIASIGSKRTTLRSLAVGGSVADVESQTKRLDTFEKALSTLDERTATLDHTANE 2155
Query: 4686 MIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEK 4507
+++ H + I + + + ++L+ E R L D+ + SD + +AW+ EK
Sbjct: 2156 LMKARHMESKNISMWQSNVHEELKLLRQDIEARHAMLKDAFALASFDSDVAQIEAWIDEK 2215
Query: 4506 -EPIVGSTDYGKDEDSAEALLKK---HRALLSDLEAFKGTIEDLRKQASQCKYQEQPMGQ 4339
+ + D + S + +K+ H+AL +++ A K ++ + ++ +Q K + +
Sbjct: 2216 TNGVRKAQDLSSESISIDEKMKRLQTHQALEAEVTANKPVVDQILQRGNQLKNLHR-NPK 2274
Query: 4338 LGRDCVLALYDYQEKSP--REVSMKKGDVLTLLN----ASNRDWWKVEVNDRQGFVPAA- 4180
+ C Y + + S + S+ + LL N W +N+++ V A
Sbjct: 2275 IANRCDELSYKWNQLSGACADQSLALEEARDLLRFKQLVENVLAW---INEKEVLVSTAD 2331
Query: 4179 ----------YVKRIE----PGTAQQHAQQQVNSIGGK--------QSEIEDKYQRL--- 4075
++R++ + ++N +G K + +++ + Q L
Sbjct: 2332 MGKDMEHCRLLLERLDGTRSDSIVDEQTLDEINRLGEKLVKQGRSSRDQVQKEQQHLNEK 2391
Query: 4074 --MMLGETR--KRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQKK 3907
++LG+ + +L A + + R+ D E I + A + G D VE+L +K
Sbjct: 2392 WRLLLGQLAHYRTELLAAMEVHTFNRDVEDTDERIHEKVAAMKSDDYGKDFASVELLVRK 2451
Query: 3906 FDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXX 3727
+ D+ A +L ++ A + + + ++ L W L
Sbjct: 2452 QSALERDMSAIHQKLIAHDKDAQKILE-KRPPLRETVLDSLKKLEESWEQLSKAAELRNE 2510
Query: 3726 QLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGD 3547
+L + ++ ++ DV + W + + + S +D + + +H + ++ +
Sbjct: 2511 KLNRSFKLYKYLDDVKKVEQWANQVRNKMTSHQTPKDSNGARKILEQHHERKAEIDGRSE 2570
Query: 3546 KIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSD 3367
+++ L E+ L Q PE ++ + + ++L + K L ++ + +
Sbjct: 2571 ELRLLHEEGQALNQEQPEHKAEVQRAHKRVQNSEHQLRQTWESEKGTLQKLLEWMLWCDE 2630
Query: 3366 YRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLN 3187
QW++ V+ EL + E L++ H + + ++ A + + L++
Sbjct: 2631 AVQCEQWLSDKETQVARGELGDTTDAVEMLIKGHSAFEETVRKQSEKIDALTKNADALVS 2690
Query: 3186 SHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAF 3007
+ DI R + V L + R ++L+ + F R C + W++A+
Sbjct: 2691 GGNNYRADIVTRSEEVTARHALLLKSMEKRGHMLEDSKKYHEFIRQCGELIIWITAK-LQ 2749
Query: 3006 LAQEDPSGD--NVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRD 2833
LA ++ D N+ S ++KH FD + E+++ ++ E L+ +NH+ S V +
Sbjct: 2750 LAYDESFLDHTNLRSKLQKHMAFDSELVENEKRLSTVERQGEQLVTDNHFMSEQVKAQLV 2809
Query: 2832 QILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTE-KFQIAQEENYRDPTNIQ 2656
++ W+ L+ K +L E+ L R ++IE W+ + + +++ +++ RD + +
Sbjct: 2810 ELRSGWDELRTKSALKTQRLREAFELHSLQRKVEDIEKWLDKVEGELSSDDHGRDILSTE 2869
Query: 2655 QKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKT 2476
+K + E+ SD + +++ L + A + + ++ L +
Sbjct: 2870 LLIKKLDTLQTEIAGRSDAVVEMMKKARELRVQGSAAADDCLKQA--EQVEARYSGLDEP 2927
Query: 2475 TTEKSYRLKEANKQKSFM-AAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEA 2299
+ L +A ++ AA +DLE WL + +L S + G L S +L KKH+ LE
Sbjct: 2928 VQIRRENLVDAQAFFQWVKAAEEDLE-WLSDRMMLASSGESGDSLQSALSLQKKHATLEK 2986
Query: 2298 DIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALN 2119
++ Q + + ++ ++ F I + ++ +K+ RRD L +A++
Sbjct: 2987 ELDTRQSAMNDTEQRGKDMIRQRHFASTHIQKILDRLSSAMLTLKESCGLRRDLLQEAID 3046
Query: 2118 VHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKL 1939
H+++ + + E W++E+ L S + GRD G ++ R+ +D E+ + ++ +K
Sbjct: 3047 AHEYYTEETEAEQWLREQMPLAMSQEMGRDQAGAESHLRRLTVLDKEVELFKNEIDRLKK 3106
Query: 1938 KGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEE 1759
+ + LL + I + LE +G + R ++ ++ + F+ ++
Sbjct: 3107 RADGLLAREHHDAM---SIAAKQRKLEALFGDLCRECARRRTQIVDASKYHKFVRQADDL 3163
Query: 1758 EAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNH 1579
W+ EK++ ++++G+++ Q ++++ ++ +L +RVA + + L+ +G+
Sbjct: 3164 SDWLREKERSASAEDYGQDLEDCQQIIEQFESTVRELAAAGERVAAVQRAQEDLLRSGHP 3223
Query: 1578 HAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQ---QV 1408
+ I + ++ + +A R L +F + D + +W+ +KE +
Sbjct: 3224 YGASITAKGADVQRLWTHVNEVANERKQALNGARQVHRFDQEADQILNWLQDKEATGVAM 3283
Query: 1407 RSEDFGR-DLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQQSPAIEKRH 1231
ED R DL+SV+ L + + F G+ A E + + + ++L +S +E R
Sbjct: 3284 EQEDLSRADLASVKAQLQRHDEFMHGMKAVEKQ-VAELCHEAERLWNSFPDTRHHLEVRR 3342
Query: 1230 TNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLTDPV 1051
++ ++ +++L ++ +E W +N + +T
Sbjct: 3343 LDMEEQLKDILEAAKKHLEKLRHMQSLQSYFQEY--------REMMQWMKNMQSTMTSEQ 3394
Query: 1050 RCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDALEDT 871
+ +L H E+ + + RR+ + + +D LE +
Sbjct: 3395 LPRDVASCESLVRRHDEYNLEMQGRKPFVDDFARQGRRMIQSSHVLSQEIQEKVDILEKS 3454
Query: 870 WRNLQRIIKEREQ------ELAREHQRQEENDKLRREFAKLANAFHAWLTNTRQEMMEAG 709
W L I K+R + ++ + Q E+ D E A L W EM E
Sbjct: 3455 WAMLCEIWKDRAELYEENMDVQKWKQNAEQLDSWLEERAGLLG--DDWRMVDSVEMAETH 3512
Query: 708 --------GTLEEQLDAVE--RKAKEIKANKGQLRQIEEKGAMLERNLILDNRYTEHSTV 559
TLE Q + + ++ ++ N +LR E ++R I ++ T+
Sbjct: 3513 LRDFDDFLVTLEAQSEKCDMVKRLTLVEQNFSRLRSKE-----IDRARIAEDDQKRRDTI 3567
Query: 558 GIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMMFKHFDKEKT 403
I + + L + Q+I S EE + D+ KT
Sbjct: 3568 KIVEKGNILANRRQERERRKTQEISLLRPSPSGEEFSTHTMPRKERKDRAKT 3619
Score = 469 bits (1208), Expect = e-130
Identities = 424/2072 (20%), Positives = 872/2072 (41%), Gaps = 64/2072 (3%)
Frame = -1
Query: 7200 ADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQTAQEEN 7021
AD IH ++L Y+ K +Q ++ L+E+R + D D WI EK A ++
Sbjct: 1528 ADRIHSTVGQLLQRYAAMKGPAQRRKGDLDESRLWHQLVFDVDCELQWIAEKKPIASSQD 1587
Query: 7020 F-RDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHAL 6844
R + ++K E EAEV H I + +I+ +H AS IK + EL
Sbjct: 1588 CGRTLTEALNMVKKQEQLEAEVNQHGGQIDKVLLQAGELIKRHHSASSQIKAKSSELETA 1647
Query: 6843 WXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQRK 6664
W + + +K ++ E+ W+ EK + +ED G D + L K
Sbjct: 1648 WSELKKLLRLRRAVVDWGVKEQQYLFDAAEVESWMNEKRNALASEDYGNDEDAARKLLSK 1707
Query: 6663 FDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEG 6484
+++ ++ + ++ +LVE ++ K++D++ + L+ LA R+
Sbjct: 1708 HRALCEDMTTYRQWLEKLEVKCVELVESNRPHVERFQKRQDELVREFDALSKLAEDRRNA 1767
Query: 6483 LFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGK 6304
L A + + R++ + I E S+++ D +++ LQ K + ++ + +
Sbjct: 1768 LEDAVCLYEYMRESADLGQSIEENLRVAMSEEFAEDYEHLKELQSKFDEFKQKVKNGSER 1827
Query: 6303 MLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADY 6124
E A+ + +P A + +K + + AWN L E + R L + +LHRF D
Sbjct: 1828 FTSCETAANAILRRNPPFARDVVKKQEALRTAWNTLCEYIEARDSKLAVAEELHRFHRDV 1887
Query: 6123 RDLISWIGDMKAVIGADELAKDVAGAEALLESHQEHKGEI---DARADSFNQTASAGQKL 5953
+ W+ D A + D L +DV +L + H+ EI R + A +K
Sbjct: 1888 DEFEQWMADKMANMPRD-LGRDVKHVHSLWQHHEALDKEIHNSQPRLAKLVEEAERLKKT 1946
Query: 5952 VEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWMNKQE 5773
G E ++ + + L+ E L ++R+ + DL F W +
Sbjct: 1947 YPGGNAE--QIGGRQQTLEQEWEELKNATDDRKDMLRAAFDLHTFNGKVRDLLAWTDLTI 2004
Query: 5772 AFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEX 5593
+ + + + L E L +H + A+E + L K+I QHYA++++
Sbjct: 2005 SDIQSDLHINDLQQAEWLQTEHSRLSHEMDAREPEFARLVNDGEKMITAQHYASEEIKNK 2064
Query: 5592 XXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSY-LDPTN 5416
R L ++ + F R+ ++++ I K +T R + +
Sbjct: 2065 THLLKSALERLRSEWALRNGFLSQAVQWHAFQREAKQIIASIGSKRTTLRSLAVGGSVAD 2124
Query: 5415 IRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDA 5236
+ + ++ FE+ L + R + T +++ + H + +I V+ L
Sbjct: 2125 VESQTKRLDTFEKALSTLDERTATLDHTANELMKARHMESKNISMWQSNVHEELKLLRQD 2184
Query: 5235 TNKKGAKLREAGNEQQFNRNIEDVEAWLSE-LEGQVASEDYGKDLVSVQNLQKKI---GL 5068
+ A L++A F+ ++ +EAW+ E G ++D + +S+ K++
Sbjct: 2185 IEARHAMLKDAFALASFDSDVAQIEAWIDEKTNGVRKAQDLSSESISIDEKMKRLQTHQA 2244
Query: 5067 IESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGE 4888
+E++ A+ VD I Q Q + H N P I + + L ++N L + L E
Sbjct: 2245 LEAEVTANKPVVDQILQRGNQL-KNLHRN-PKIANRCDELSYKWNQLSGACADQSLALEE 2302
Query: 4887 SHQGNQLFRDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIES 4708
+ + + +E+ LAWI EKE + + + G+D+ + L+++ ++ + ++
Sbjct: 2303 ARDLLRFKQLVENVLAWINEKEVLVSTADMGKDMEHCRLLLERLDGTRSDSIVDEQTLDE 2362
Query: 4707 VSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEA 4528
++ +++QG +++ + L + WR+L + RT+L +++ H + D +
Sbjct: 2363 INRLGEKLVKQGRSSRDQVQKEQQHLNEKWRLLLGQLAHYRTELLAAMEVHTFNRDVEDT 2422
Query: 4527 DAWMSEKEPIVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIEDLRKQASQCKYQEQP 4348
D + EK + S DYGKD S E L++K AL D+ A + K A + + P
Sbjct: 2423 DERIHEKVAAMKSDDYGKDFASVELLVRKQSALERDMSAIHQKLIAHDKDAQKILEKRPP 2482
Query: 4347 MGQLGRDCVLALYDYQEKSPREVSMKKGDV-------LTLLNASNRDWWKVEVNDRQGFV 4189
+ + D + L + E+ + ++ + L + + W +V ++
Sbjct: 2483 LRETVLDSLKKLEESWEQLSKAAELRNEKLNRSFKLYKYLDDVKKVEQWANQVRNKMTSH 2542
Query: 4188 PAAYVKRIEPGTAQQHAQQQVNSIGGKQSE----------------------------IE 4093
+QH +++ I G+ E ++
Sbjct: 2543 QTPKDSNGARKILEQHHERKA-EIDGRSEELRLLHEEGQALNQEQPEHKAEVQRAHKRVQ 2601
Query: 4092 DKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQVEVLQ 3913
+ +L E+ K L++ + EA +W+ +E A+ E+G + VE+L
Sbjct: 2602 NSEHQLRQTWESEKGTLQKLLEWMLWCDEAVQCEQWLSDKETQVARGELGDTTDAVEMLI 2661
Query: 3912 KKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXX 3733
K F+ ++ ++ + + A AL S G A I + E++ AR L
Sbjct: 2662 KGHSAFEETVRKQSEKIDALTKNADALVSGGNNYRA-DIVTRSEEVTARHALLLKSMEKR 2720
Query: 3732 XXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAAL 3553
L + + F R E WI K E F D ++++ +KH + +L
Sbjct: 2721 GHMLEDSKKYHEFIRQCGELIIWITAKLQLAYDESF-LDHTNLRSKLQKHMAFDSELVEN 2779
Query: 3552 GDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFL 3373
++ +++ + +L + +EQ+ EL W+ L +K+ + ++L ++++
Sbjct: 2780 EKRLSTVERQGEQLVTDNHFMSEQVKAQLVELRSGWDELRTKSALKTQRLREAFELHSLQ 2839
Query: 3372 SDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQL 3193
D+ +W+ + +SS + D+ E L+++ +TEI R+ + +L
Sbjct: 2840 RKVEDIEKWLDKVEGELSSDDHGRDILSTELLIKKLDTLQTEIAGRSDAVVEMMKKAREL 2899
Query: 3192 LNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSARE 3013
AA D + + V GL++ RR L + + E+ W+S R
Sbjct: 2900 RVQGSAAADDCLKQAEQVEARYSGLDEPVQIRRENLVDAQAFFQWVKAAEEDLEWLSDR- 2958
Query: 3012 AFLAQEDPSGDNVE---SLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTR 2842
LA SGD+++ SL KKH +K ++T++ + + + +I+ H+ S + +
Sbjct: 2959 MMLASSGESGDSLQSALSLQKKHATLEKELDTRQSAMNDTEQRGKDMIRQRHFASTHIQK 3018
Query: 2841 KRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIA-QEENYRDPT 2665
D++ LKE+ +R L E+ ++ + E E W+ E+ +A +E RD
Sbjct: 3019 ILDRLSSAMLTLKESCGLRRDLLQEAIDAHEYYTEETEAEQWLREQMPLAMSQEMGRDQA 3078
Query: 2664 NIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLL 2485
+ ++ + E+ + I + + + L+ A+ +++A+ + L + L
Sbjct: 3079 GAESHLRRLTVLDKEVELFKNEIDRLKKRADGLL--AREHHDAMSIAAKQRKLEALFGDL 3136
Query: 2484 VKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLL 2305
+ + ++ +A+K F+ DL WL E E +EDYG+DL + ++++
Sbjct: 3137 CRECARRRTQIVDASKYHKFVRQADDLSDWLREKERSASAEDYGQDLEDCQQIIEQFEST 3196
Query: 2304 EADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKA 2125
++ A +RV + + LL + G I + + + V ++A +R+ L+ A
Sbjct: 3197 VRELAAAGERVAAVQRAQEDLLRSGHPYGASITAKGADVQRLWTHVNEVANERKQALNGA 3256
Query: 2124 LNVHQFFRDIDDEESWIKEKK---LLVSSDDYGR-DLPGVQNLRRKHRRIDTELASHEPQ 1957
VH+F ++ D +W+++K+ + + +D R DL V+ ++H + + E Q
Sbjct: 3257 RQVHRFDQEADQILNWLQDKEATGVAMEQEDLSRADLASVKAQLQRHDEFMHGMKAVEKQ 3316
Query: 1956 VSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFL 1777
V+ + + E L S + ++ R D+E+ I + ++L ++ Q++
Sbjct: 3317 VAELCHEAERLWNSFPDT---RHHLEVRRLDMEEQLKDILEAAKKHLEKLRHMQSLQSYF 3373
Query: 1776 GDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTL 1597
+ E WM Q + S+ ++A + L+++HD + ++++ K V D +G +
Sbjct: 3374 QEYREMMQWMKNMQSTMTSEQLPRDVASCESLVRRHDEYNLEMQGRKPFVDDFARQGRRM 3433
Query: 1596 IHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKE 1417
I + + + I+++ D L + + + R +N ++ + ++SW+ E+
Sbjct: 3434 IQSSHVLSQEIQEKVDILEKSWAMLCEIWKDRAELYEENMDVQKWKQNAEQLDSWLEERA 3493
Query: 1416 QQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEG-----IQRITELK---DQLVSSEH 1261
+ D R + SV++ T FD L E + ++R+T ++ +L S E
Sbjct: 3494 GLL--GDDWRMVDSVEMAETHLRDFDDFLVTLEAQSEKCDMVKRLTLVEQNFSRLRSKEI 3551
Query: 1260 QQSPAIE----KRHTNVIQRWQNLLAHSEARR 1177
++ E +R T I N+LA+ R
Sbjct: 3552 DRARIAEDDQKRRDTIKIVEKGNILANRRQER 3583
Score = 400 bits (1027), Expect = e-109
Identities = 461/2359 (19%), Positives = 966/2359 (40%), Gaps = 113/2359 (4%)
Frame = -1
Query: 7221 EIRILETADDIHQRRQE---VLGHYSIFKDHSQTKRDRLEEARQFQY------------- 7090
EI L A+D+ R + ++ + S++ H ++ + AR+
Sbjct: 244 EIARLLDAEDVDVTRPDEKSIITYVSLYYHHFAKQKTEMTGARRIANIVGKLMVSETMED 303
Query: 7089 -FKRDADELNVWILEKLQTAQEENFRDPSNLQAKIQKHEAF--------------EAEVQ 6955
++ A EL WI ++T + F P++L ++H F + E++
Sbjct: 304 DYEHIASELLNWIRVTIKTLESRRF--PNSLNGMREEHAKFNQFRTSEKPPKYKEKGELE 361
Query: 6954 AHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHALWXXXXXXXXXKGIKLQQALKLLH 6775
A TI K AM + + + + + ++ + W + + + L+
Sbjct: 362 ALFFTIQTKRK---AMSRKQYQPPQGLF--MHDIESAWAQLDYAENERQVAIIAELQRQE 416
Query: 6774 FIRQCDEILY--------WIREKETYVTAEDMGMDLEHVEILQRKFDDFLKELGNHQYRI 6619
+ Q + + W+R + + + G VE +K ++ + R
Sbjct: 417 KLEQLAQRFHKKAKLRDSWLRSVQVVLEEMEHGRSASQVEKTLKKQQAISTDILAREDRF 476
Query: 6618 NEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKEGLFGAHQVQRFNRDAD 6439
+ ++L E + E D++ ++ D W +L TL RK L + + RD D
Sbjct: 477 KMLTAMCNELCTEKYHESDKVRGMEREIIDRWTQLLTLLEQRKRALMSLNDLMSLLRDID 536
Query: 6438 ETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEGKMLQLEKEAHKLAETH 6259
+ + A+ + D G+ L V+ L KH+ + + A + +L + A+
Sbjct: 537 TLSNELYSLEPAVRNRDVGKHLIGVEDLLGKHDLLDAQINAHGSLLSKLSQSANNYIRHK 596
Query: 6258 PDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLADYRDLISWIGDMKAVIG 6079
++ + + +K D+ A +N L E + R+ GLER+ L +F+ D+ + ++W+ + + +
Sbjct: 597 EEQFDVLQRKLDEVTAQYNTLVELCRSRRLGLERARSLFQFVQDHEEEMAWLAEKEKLCT 656
Query: 6078 ADELAKDVAGAEALLESHQEHKGEIDARADSFNQTASAGQKLVEMGIPESPEVQEKLEKL 5899
+ D++ ++ + E+ + G++LV+ G ++Q +L ++
Sbjct: 657 TALNSGDISAVPQTTLLYKNVEMEMQTHWARSKGMIAGGERLVQNG-QSKEDIQRRLTQM 715
Query: 5898 DHEKSSLLGLWEERRILYE-------QCMDLQLFYRDTEQAETWMNKQEAFLANTDLGDS 5740
+H WE R+ + + Q +++D +AE+W+ ++ + + DLG
Sbjct: 716 NHR-------WERLRVAVDALGNWLSEARHAQQYFQDANEAESWIREKMPLVKSDDLGRD 768
Query: 5739 LDSVEHLIKKHEDFEKSLAAQEEKINALDEFATKLIQGQHYAADDVAEXXXXXXXXXXXX 5560
+ E L+++H E+ + A + I+ L+E ++L + A
Sbjct: 769 EGAAESLLQRHARLEEEIRAYKSDISRLEEMQSQLANSAFHTATTSQSVQETEEVNVPQV 828
Query: 5559 XXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDDSYLDPTNIRGKLQKHINFE 5380
GN ++ S V + EK ST L G + N+
Sbjct: 829 EMSYNYEGNGMRVSKGE----------VLALLEK-STPEWWRALKRDGTEGYVP--ANYC 875
Query: 5379 QELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNLWNELVDATNKKGAKLREAG 5200
+ + + ++ + + DR +++N + EL + + L +
Sbjct: 876 KIVPGETVTVTQTTQKTTTTLEGNETKSSVVADRQHKISNDYRELKRLADVRRRLLSDNI 935
Query: 5199 NEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKKIGLIESDFNAH-NDRVDGI 5023
+F R ++ E W E+E +A E + + + ++K +E+D + ++ I
Sbjct: 936 KLLRFYRECDEFERWAKEIEVSLADEPSPEHVAA---FRRKFDKLEADMKTNGGTQLKHI 992
Query: 5022 KQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRKLGESHQGNQLFRDI---- 4855
+A E H + RK E Q + NA+ D LE+ +++ G + + D
Sbjct: 993 NDIANDLISEGHGQS----RKIEVRQHKINAMWDNLERLRKQRGVRLEATERVADFDTTC 1048
Query: 4854 EDELAWIREK-EQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDSQIESVSSAANDMIQ 4678
E W+ K EQ+ + N D+ +QNL + + L +IA +E +++A ++
Sbjct: 1049 ESAREWMLSKFEQLDRNPN---DVKSLQNLERDLKPLEDKIA----ALEKLAAA----VK 1097
Query: 4677 QGH-FLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSDANEADAWMSEKEP 4501
+ H A I K+A+LR L +A+++ + + + S + W+ +
Sbjct: 1098 KDHPEEAAAIERKIAELRALHADLLRRAQEKMLLAEQTQGKEMFESALRDMIGWIEKTRK 1157
Query: 4500 IVGSTDYGKDEDSAEALLKKHRALLSDLEAFKGTIED--------LRKQASQCKYQEQPM 4345
++ + D AE LLKKH L ++ K +E L + K +EQ
Sbjct: 1158 VMMEDVHPVDVAEAEELLKKHYELGEQIKDKKYEVEYCQELGRRLLERNPRMSKVEEQLQ 1217
Query: 4344 GQLG-----------RDCVLA----LYDYQEKSPREVSMKKG------------DVLTLL 4246
+ RD +L L + +S R + KG V ++
Sbjct: 1218 NLVSEMASLRDLYRRRDTILKQQLDLQLFNRESERIDAATKGHEAFLEFDNLGDSVESVE 1277
Query: 4245 NASNRDWWKVEVNDRQGFVPAAYVKRIEPGTAQQHAQQQVNSIGGKQSEIEDKYQRLMML 4066
N R D Q A+ + + QHA I ++ ++ + + +
Sbjct: 1278 NLLKRHRDLEAKLDAQEARLEAFSRTADDMIKAQHADSAY--IEQRRRDVLARREAVRRA 1335
Query: 4065 GETRKRKLEEACKGYQLLREANDLAEWI-KSREAVAAQQEIGTDLEQVEVLQKKFDDFKG 3889
RK++LE + + ++ REA+++ W+ + + V + + + K + F+
Sbjct: 1336 AAQRKKQLEASLEYQEMRREADEVVGWMYEKAKLVMSGDDSALAPSAIPHRLLKHEAFEA 1395
Query: 3888 DLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIEDLNARWRALXXXXXXXXXQLGSAH 3709
++ ANE R+Q++N L S E+ + + + +NA+W L +L A
Sbjct: 1396 EIIANEPRIQQINSEGDGLVSKKHYESP-NVEKIVRQVNAQWGDLKKQVWNKGLRLRQAA 1454
Query: 3708 EVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQRKHEGVERDLAALGDKIKSLD 3529
+ + R +++ + E AL+S+D G DLRSV+ L +KH +E+++ G+K+ ++
Sbjct: 1455 DQKGLDRILEDAHAKLDEMQTALNSKDQGLDLRSVKDLLQKHAVLEQEMGLYGNKLSDIE 1514
Query: 3528 EKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRKEKLLDSYDYQRFLSDYRDLMQ 3349
+ ++ A++I+ +L +++ + A RK L +S + + + D +Q
Sbjct: 1515 NRGKKMAVDGHYDADRIHSTVGQLLQRYAAMKGPAQRRKGDLDESRLWHQLVFDVDCELQ 1574
Query: 3348 WIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRAATFQAFDQFGNQLLNSHHYAA 3169
WIA + SSQ+ +T A ++++ ++ E++ +L+ HH A+
Sbjct: 1575 WIAEKKPIASSQDCGRTLTEALNMVKKQEQLEAEVNQHGGQIDKVLLQAGELIKRHHSAS 1634
Query: 3168 GDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYRDCEQADTWMSAREAFLAQEDP 2989
I+ + + A L+ RR ++D ++ Q + D + ++WM+ + LA ED
Sbjct: 1635 SQIKAKSSELETAWSELKKLLRLRRAVVDWGVKEQQYLFDAAEVESWMNEKRNALASEDY 1694
Query: 2988 SGDN--VESLIKKHEDFDKAINTQEEKIKGLKLFAESLIKNNHYDSPAVTRKRDQILDRW 2815
D L+ KH + + T + ++ L++ L+++N +++D+++ +
Sbjct: 1695 GNDEDAARKLLSKHRALCEDMTTYRQWLEKLEVKCVELVESNRPHVERFQKRQDELVREF 1754
Query: 2814 NGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQIAQEENY-RDPTNIQQKHQKQ 2638
+ L + +R L ++ L ++ R++ ++ + E ++A E + D ++++ K
Sbjct: 1755 DALSKLAEDRRNALEDAVCLYEYMRESADLGQSIEENLRVAMSEEFAEDYEHLKELQSKF 1814
Query: 2637 QAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEAAVSARLKALNDQWDLLVKTTTEKSY 2458
F+ ++ S+R + A N ++ + V + +AL W+ L + +
Sbjct: 1815 DEFKQKVKNGSERFTSCETAANAILRRNPPFARD--VVKKQEALRTAWNTLCEYIEARDS 1872
Query: 2457 RLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDLASVENLLKKHSLLEADIVAHQD 2278
+L A + F V + E W+ + ++ D G+D+ V +L + H L+ +I Q
Sbjct: 1873 KLAVAEELHRFHRDVDEFEQWMAD-KMANMPRDLGRDVKHVHSLWQHHEALDKEIHNSQP 1931
Query: 2277 RVGEMNEQADSLLEN-DQFQGQQIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFR 2101
R+ ++ E+A+ L + +QI R++ + ++ +K DR+D L A ++H F
Sbjct: 1932 RLAKLVEEAERLKKTYPGGNAEQIGGRQQTLEQEWEELKNATDDRKDMLRAAFDLHTFNG 1991
Query: 2100 DIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELL 1921
+ D +W + SD + DL + L+ +H R+ E+ + EP+ + + GE+++
Sbjct: 1992 KVRDLLAWTDLTISDIQSDLHINDLQQAEWLQTEHSRLSHEMDAREPEFARLVNDGEKMI 2051
Query: 1920 RSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNE 1741
+ A ++IK + L+ + ++R R+ L ++ + AF + ++ A +
Sbjct: 2052 TAQHYA---SEEIKNKTHLLKSALERLRSEWALRNGFLSQAVQWHAFQREAKQIIASIGS 2108
Query: 1740 KQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIK 1561
K+ L S G ++A V+ K+ DTF+ L +R A L + + L+ + + +I
Sbjct: 2109 KRTTLRSLAVGGSVADVESQTKRLDTFEKALSTLDERTATLDHTANELMKARHMESKNIS 2168
Query: 1560 QRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGRDL 1381
+ L + E R A L+D A F +E+WI EK VR +DL
Sbjct: 2169 MWQSNVHEELKLLRQDIEARHAMLKDAFALASFDSDVAQIEAWIDEKTNGVRK---AQDL 2225
Query: 1380 SSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSEHQ-----QSPAIEKRHTNVIQ 1216
SS I + ++ A E E + + DQ++ +Q ++P I R +
Sbjct: 2226 SSESISIDEKMKRLQTHQALEAE-VTANKPVVDQILQRGNQLKNLHRNPKIANRCDELSY 2284
Query: 1215 RWQNL--------LAHSEARRXXXXXXXXXXXQIEELYLAFAKKASTFNSWFENAEEDLT 1060
+W L LA EAR L F + +W E ++
Sbjct: 2285 KWNQLSGACADQSLALEEARD----------------LLRFKQLVENVLAWINEKEVLVS 2328
Query: 1059 DPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLDRRIKSFNVGPNPYTWFTMDAL 880
+E R L + + E+ ++ L ++ L
Sbjct: 2329 TADMGKDMEHCRLLLERLDGTRSDSIVDEQTLDEINRLGEKLVKQGRSSRDQVQKEQQHL 2388
Query: 879 EDTWRNLQRIIKEREQELAR-------EHQRQEENDKLRREFAKLANAFHAWLTNTRQEM 721
+ WR L + EL ++ ++++ + A + + + + + +
Sbjct: 2389 NEKWRLLLGQLAHYRTELLAAMEVHTFNRDVEDTDERIHEKVAAMKSDDYGKDFASVELL 2448
Query: 720 MEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERNLILDNRYTEHSTVGIAQAW 541
+ LE + A+ +K + A+ ++I EK L R +LD S + ++W
Sbjct: 2449 VRKQSALERDMSAIHQK---LIAHDKDAQKILEKRPPL-RETVLD------SLKKLEESW 2498
Query: 540 DQLDQLAMRMQHNLEQQIQ 484
+QL + A L + +
Sbjct: 2499 EQLSKAAELRNEKLNRSFK 2517
Score = 394 bits (1011), Expect = e-107
Identities = 463/2289 (20%), Positives = 934/2289 (40%), Gaps = 88/2289 (3%)
Frame = -1
Query: 7200 ADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELN--VWILEKLQTAQE 7027
+D + +E++ ++ + ++ L RD D L+ ++ LE ++
Sbjct: 494 SDKVRGMEREIIDRWTQLLTLLEQRKRALMSLNDLMSLLRDIDTLSNELYSLEPAVRNRD 553
Query: 7026 ENFRDPSNLQAKIQKHEAFEAEVQAHAKTIANLDKTGNAMIQHNHFASEHIKKRLEELHA 6847
+ ++ + KH+ +A++ AH ++ L ++ N I+H + ++++L+E+ A
Sbjct: 554 VG-KHLIGVEDLLGKHDLLDAQINAHGSLLSKLSQSANNYIRHKEEQFDVLQRKLDEVTA 612
Query: 6846 LWXXXXXXXXXKGIKLQQALKLLHFIRQCDEILYWIREKETYVTAEDMGMDLEHVEILQR 6667
+ + + L++A L F++ +E + W+ EKE T D+ V
Sbjct: 613 QYNTLVELCRSRRLGLERARSLFQFVQDHEEEMAWLAEKEKLCTTALNSGDISAVPQTTL 672
Query: 6666 KFDDFLKELGNHQYRINEINQAADKLVEEGHSEHDQIYKKRDDVNDAWHRLNTLAATRKE 6487
+ + E+ H R + ++LV+ G S+ D I ++ +N W RL
Sbjct: 673 LYKNVEMEMQTHWARSKGMIAGGERLVQNGQSKED-IQRRLTQMNHRWERLRVAVDALGN 731
Query: 6486 GLFGAHQVQRFNRDADETLAWIGEKDLALSSDDYGRDLNNVQALQRKHEGTERDLAALEG 6307
L A Q++ +DA+E +WI EK + SDD GRD ++L ++H E ++ A +
Sbjct: 732 WLSEARHAQQYFQDANEAESWIREKMPLVKSDDLGRDEGAAESLLQRHARLEEEIRAYKS 791
Query: 6306 KMLQLEKEAHKLAETHPDRAEAIHQKNDDTKAAWNALKEKAQHRKDGLERSFQLHRFLAD 6127
+ +LE+ +LA + A H T +++E + +E S+ +
Sbjct: 792 DISRLEEMQSQLANS------AFH-----TATTSQSVQETEEVNVPQVEMSYNY-----E 835
Query: 6126 YRDLISWIGDMKAVIGADE------LAKDVAGAEALLESHQEHKGEIDARADSFNQTASA 5965
+ G++ A++ L +D G E + ++ + + + QT
Sbjct: 836 GNGMRVSKGEVLALLEKSTPEWWRALKRD--GTEGYVPAN--YCKIVPGETVTVTQTTQK 891
Query: 5964 GQKLVEMGIPESPEVQEKLEKLDHEKSSLLGLWEERRILYEQCMDLQLFYRDTEQAETWM 5785
+E +S V ++ K+ ++ L L + RR L + L FYR+ ++ E W
Sbjct: 892 TTTTLEGNETKSSVVADRQHKISNDYRELKRLADVRRRLLSDNIKLLRFYRECDEFERWA 951
Query: 5784 NKQEAFLANTDLGDSLDSVEHLIKKHEDFEKSLAAQE----EKINALDEFATKLIQGQHY 5617
+ E LA+ S EH+ F+K A + ++ +++ A LI H
Sbjct: 952 KEIEVSLADE------PSPEHVAAFRRKFDKLEADMKTNGGTQLKHINDIANDLISEGHG 1005
Query: 5616 AADDVAEXXXXXXXXXXXXXXXXXXRGNALKESYKRQTFDRDCDEMVSWITEKLSTARDD 5437
+ + RG L+ + + FD C+ W+ K +
Sbjct: 1006 QSRKIEVRQHKINAMWDNLERLRKQRGVRLEATERVADFDTTCESAREWMLSKF----EQ 1061
Query: 5436 SYLDPTNIRGKLQKHINFEQELKANENRLDDIRSTGEQIIDSGHFAADHIGDRLRQVNNL 5257
+P +++ LQ N E++LK E+++ + + A I ++ ++ L
Sbjct: 1062 LDRNPNDVK-SLQ---NLERDLKPLEDKIAALEKLAAAVKKDHPEEAAAIERKIAELRAL 1117
Query: 5256 WNELVDATNKKGAKLREAGNEQQFNRNIEDVEAWLSELEGQVASEDYGKDLVSVQNLQKK 5077
+L+ +K + ++ F + D+ W+ + + + + D+ + L KK
Sbjct: 1118 HADLLRRAQEKMLLAEQTQGKEMFESALRDMIGWIEKTRKVMMEDVHPVDVAEAEELLKK 1177
Query: 5076 IGLIESDFNAHNDRVDGIKQLAQQFQEEEHFNAPVIVRKQENLQQRYNALRDPLEKRKRK 4897
+ V+ ++L ++ E + + +NL +LRD L +R+
Sbjct: 1178 HYELGEQIKDKKYEVEYCQELGRRLLERNP-RMSKVEEQLQNLVSEMASLRD-LYRRRDT 1235
Query: 4896 LGESHQGNQLF-RDIEDELAWIREKEQVAGSTNRGRDLIGVQNLIKKQQALIAEIANHDS 4720
+ + QLF R+ E A + E N G + V+NL+K+ + L A++ ++
Sbjct: 1236 ILKQQLDLQLFNRESERIDAATKGHEAFLEFDNLGDSVESVENLLKRHRDLEAKLDAQEA 1295
Query: 4719 QIESVSSAANDMIQQGHFLAPEIRDKLAQLRDNWRILKSKAEKRRTDLDDSLQAHQYLSD 4540
++E+ S A+DMI+ H + I + + ++ A +R+ L+ SL+ + +
Sbjct: 1296 RLEAFSRTADDMIKAQHADSAYIEQRRRDVLARREAVRRAAAQRKKQLEASLEYQEMRRE 1355
Query: 4539 ANEADAWMSEKEPIVGSTDYGKDEDSA-EALLKKHRALLSDLEAFKGTIEDLRKQ----A 4375
A+E WM EK +V S D SA L KH A +++ A + I+ + +
Sbjct: 1356 ADEVVGWMYEKAKLVMSGDDSALAPSAIPHRLLKHEAFEAEIIANEPRIQQINSEGDGLV 1415
Query: 4374 SQCKYQEQPMGQLGRDCVLALYDYQEK------SPREVSMKKGDVLTLLNA-SNRDWWKV 4216
S+ Y+ + ++ R D +++ R+ + +KG L +A + D +
Sbjct: 1416 SKKHYESPNVEKIVRQVNAQWGDLKKQVWNKGLRLRQAADQKGLDRILEDAHAKLDEMQT 1475
Query: 4215 EVNDRQGFVPAAYVKRIEPGTAQQHA--QQQVNSIGGKQSEIEDKYQRLMMLG------- 4063
+N + + VK + Q+HA +Q++ G K S+IE++ +++ + G
Sbjct: 1476 ALNSKDQGLDLRSVKDL----LQKHAVLEQEMGLYGNKLSDIENRGKKMAVDGHYDADRI 1531
Query: 4062 ------------------ETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTD 3937
+ RK L+E+ +QL+ + + +WI ++ +A+ Q+ G
Sbjct: 1532 HSTVGQLLQRYAAMKGPAQRRKGDLDESRLWHQLVFDVDCELQWIAEKKPIASSQDCGRT 1591
Query: 3936 LEQVEVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQT-----ETAVRIRQQIEDLN 3772
L + + KK + + ++ Q QI L G+ + +I+ + +L
Sbjct: 1592 LTEALNMVKKQEQLEAEVN------QHGGQIDKVLLQAGELIKRHHSASSQIKAKSSELE 1645
Query: 3771 ARWRALXXXXXXXXXQLGSAHEVQRFHRDVDETRDWIQEKDDALDSEDFGRDLRSVQALQ 3592
W L + + Q++ D E W+ EK +AL SED+G D + + L
Sbjct: 1646 TAWSELKKLLRLRRAVVDWGVKEQQYLFDAAEVESWMNEKRNALASEDYGNDEDAARKLL 1705
Query: 3591 RKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLTSKANNRK 3412
KH + D+ ++ L+ K L +S+ E+ Q EL +++ L+ A +R+
Sbjct: 1706 SKHRALCEDMTTYRQWLEKLEVKCVELVESNRPHVERFQKRQDELVREFDALSKLAEDRR 1765
Query: 3411 EKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYRTEIDSRA 3232
L D+ ++ + DL Q I ++ S+E A D + L + E++ ++ + +
Sbjct: 1766 NALEDAVCLYEYMRESADLGQSIEENLRVAMSEEFAEDYEHLKELQSKFDEFKQKVKNGS 1825
Query: 3231 ATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCLELQLFYR 3052
F + + N +L + A D+ + + + A L + AR + L EL F+R
Sbjct: 1826 ERFTSCETAANAILRRNPPFARDVVKKQEALRTAWNTLCEYIEARDSKLAVAEELHRFHR 1885
Query: 3051 DCEQADTWMSAREAFLAQE-DPSGDNVESLIKKHEDFDKAINTQEEKIKGLKLFAESLIK 2875
D ++ + WM+ + A + ++ +V SL + HE DK I+ + ++ L AE L K
Sbjct: 1886 DVDEFEQWMADKMANMPRDLGRDVKHVHSLWQHHEALDKEIHNSQPRLAKLVEEAERLKK 1945
Query: 2874 NNHYDSPAVTRKRDQILDR-WNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQ 2698
+ R Q L++ W LK A ++ L + L F+ ++ W
Sbjct: 1946 TYPGGNAEQIGGRQQTLEQEWEELKNATDDRKDMLRAAFDLHTFNGKVRDLLAWTDLTIS 2005
Query: 2697 IAQEE-NYRDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGGGEA---- 2533
Q + + D + + E+ A A ++ G +I E
Sbjct: 2006 DIQSDLHINDLQQAEWLQTEHSRLSHEMDAREPEFARLVNDGEKMITAQHYASEEIKNKT 2065
Query: 2532 -AVSARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDY 2356
+ + L+ L +W L ++ L +A + +F K + +G L+S
Sbjct: 2066 HLLKSALERLRSEWAL-------RNGFLSQAVQWHAFQREAKQIIASIGSKRTTLRSLAV 2118
Query: 2355 GKDLASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRY 2176
G +A VE+ K+ E + +R ++ A+ L++ + + I+ + + +
Sbjct: 2119 GGSVADVESQTKRLDTFEKALSTLDERTATLDHTANELMKARHMESKNISMWQSNVHEEL 2178
Query: 2175 DGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLV-SSDDYGRDLPGVQNLRRK 1999
+++ R L A + F D+ E+WI EK V + D + + ++
Sbjct: 2179 KLLRQDIEARHAMLKDAFALASFDSDVAQIEAWIDEKTNGVRKAQDLSSESISIDEKMKR 2238
Query: 1998 ---HRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLT 1828
H+ ++ E+ +++P V + +G +L +I R ++L W Q+
Sbjct: 2239 LQTHQALEAEVTANKPVVDQILQRGNQLKNLHR-----NPKIANRCDELSYKWNQLSGAC 2293
Query: 1827 GNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDL 1648
++ L+E+ F VE AW+NEK+ ++ + + G++M + LL++ D + D
Sbjct: 2294 ADQSLALEEARDLLRFKQLVENVLAWINEKEVLVSTADMGKDMEHCRLLLERLDGTRSDS 2353
Query: 1647 ELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDN--SA 1474
+ +Q + ++ G+ L+ G +++ + L E + G+LA R +A
Sbjct: 2354 IVDEQTLDEINRLGEKLVKQGRSSRDQVQKE----QQHLNEKWRLLLGQLAHYRTELLAA 2409
Query: 1473 YLQFMWKCDV--VESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGI-- 1306
+ DV + I EK ++S+D+G+D +SV++L+ KQ A + ++A + I
Sbjct: 2410 MEVHTFNRDVEDTDERIHEKVAAMKSDDYGKDFASVELLVRKQSALERDMSAIHQKLIAH 2469
Query: 1305 ----QRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQI 1138
Q+I E + L + +E + W+ L +E R
Sbjct: 2470 DKDAQKILEKRPPLRETVLDSLKKLE-------ESWEQLSKAAELRNEKLNRSFKLYK-- 2520
Query: 1137 EELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQ 958
YL KK W +T R + + H E + + E+ R
Sbjct: 2521 ---YLDDVKKV---EQWANQVRNKMTSHQTPKDSNGARKILEQHHERKAEIDGRSEELRL 2574
Query: 957 LQDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRRE 778
L + + + ++ + + + ++ EHQ ++ + +
Sbjct: 2575 LHEEGQALN-----------------QEQPEHKAEVQRAHKRVQNSEHQLRQTWESEKGT 2617
Query: 777 FAKL---------ANAFHAWLTNTRQEMMEAGGTLEEQLDAVERKAKEIKANKGQLRQIE 625
KL A WL++ +E A G L + DAVE K A + +R+
Sbjct: 2618 LQKLLEWMLWCDEAVQCEQWLSD--KETQVARGELGDTTDAVEMLIKGHSAFEETVRKQS 2675
Query: 624 EKGAMLERN 598
EK L +N
Sbjct: 2676 EKIDALTKN 2684
Score = 179 bits (454), Expect = 9e-43
Identities = 263/1342 (19%), Positives = 521/1342 (38%), Gaps = 35/1342 (2%)
Frame = -1
Query: 4284 EVSMKKGDVLTLLNASNRDWWKVEVNDRQGFVPAAYVKRIEPGTAQQHAQQQVNSIGGKQ 4105
+V+ KK ++ LL+A + D + + +V Y + T A++ N +G
Sbjct: 237 DVAEKKLEIARLLDAEDVDVTRPDEKSIITYVSLYYHHFAKQKTEMTGARRIANIVGK-- 294
Query: 4104 SEIEDKYQRLMMLGETRKRKLEEACKGYQLLREANDLAEWIKSREAVAAQQEIGTDLEQV 3925
+M+ ET + E A++L WI+ + L +
Sbjct: 295 ----------LMVSETMEDDYEHI---------ASELLNWIRVTIKTLESRRFPNSLNGM 335
Query: 3924 EVLQKKFDDFKGDLKANEVRLQEMNQIATALTSVGQTETAVRIRQQIE--------DLNA 3769
KF+ F+ K + + E ++ ++ QT+ R+Q + D+ +
Sbjct: 336 REEHAKFNQFRTSEKPPKYK--EKGELEALFFTI-QTKRKAMSRKQYQPPQGLFMHDIES 392
Query: 3768 RWRALXXXXXXXXXQLGSAHE--------VQRFHRDVDETRDWIQEKDDALDSEDFGRDL 3613
W L + + + QRFH+ W++ L+ + GR
Sbjct: 393 AWAQLDYAENERQVAIIAELQRQEKLEQLAQRFHKKAKLRDSWLRSVQVVLEEMEHGRSA 452
Query: 3612 RSVQALQRKHEGVERDLAALGDKIKSLDEKANRLRQSHPEAAEQIYDLQRELNEQWNRLT 3433
V+ +K + + D+ A D+ K L N L ++++ ++RE+ ++W +L
Sbjct: 453 SQVEKTLKKQQAISTDILAREDRFKMLTAMCNELCTEKYHESDKVRGMEREIIDRWTQLL 512
Query: 3432 SKANNRKEKLLDSYDYQRFLSDYRDLMQWIASMNQLVSSQELANDVTGAEALLERHQEYR 3253
+ RK L+ D L D L + S+ V ++++ + G E LL +H
Sbjct: 513 TLLEQRKRALMSLNDLMSLLRDIDTLSNELYSLEPAVRNRDVGKHLIGVEDLLGKHDLLD 572
Query: 3252 TEIDSRAATFQAFDQFGNQLLNSHHYAAGDIENRLQGVNEARKGLEDAWVARRNILDQCL 3073
+I++ + Q N + ++ +L V L + +RR L++
Sbjct: 573 AQINAHGSLLSKLSQSANNYIRHKEEQFDVLQRKLDEVTAQYNTLVELCRSRRLGLERAR 632
Query: 3072 ELQLFYRDCEQADTWMSAREAFLAQEDPSGD--NVESLIKKHEDFDKAINTQEEKIKGLK 2899
L F +D E+ W++ +E SGD V +++ + + T + KG+
Sbjct: 633 SLFQFVQDHEEEMAWLAEKEKLCTTALNSGDISAVPQTTLLYKNVEMEMQTHWARSKGMI 692
Query: 2898 LFAESLIKNNHYDSPAVTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIEN 2719
E L++N + R+ Q+ RW L+ A+ L E++ QQ+ +DA+E E+
Sbjct: 693 AGGERLVQNGQ-SKEDIQRRLTQMNHRWERLRVAVDALGNWLSEARHAQQYFQDANEAES 751
Query: 2718 WMTEKFQIAQEENY-RDPTNIQQKHQKQQAFEAELHANSDRIAAIIQAGNNLIENAKCGG 2542
W+ EK + + ++ RD + Q+ E E+ A I+ + + + L +A
Sbjct: 752 WIREKMPLVKSDDLGRDEGAAESLLQRHARLEEEIRAYKSDISRLEEMQSQLANSA---- 807
Query: 2541 GEAAVSARLKALNDQWDLLVKTTTEKSYRLKEAN---KQKSFMAAVKDLEFWLGEVEILL 2371
TT++ +E N + S+ + GEV LL
Sbjct: 808 -----------------FHTATTSQSVQETEEVNVPQVEMSYNYEGNGMRVSKGEVLALL 850
Query: 2370 QSEDYGKDLASVENLLKKHSLLEADIVAHQDR--------VGEMNEQADSLLENDQFQGQ 2215
+ K LK+ E + A+ + V + ++ + LE ++ +
Sbjct: 851 E-----KSTPEWWRALKRDG-TEGYVPANYCKIVPGETVTVTQTTQKTTTTLEGNETKSS 904
Query: 2214 QIAERRKLIADRYDGVKKMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYG 2035
+A+R+ I++ Y +K++A RR LS + + +F+R+ D+ E W KE ++ ++
Sbjct: 905 VVADRQHKISNDYRELKRLADVRRRLLSDNIKLLRFYRECDEFERWAKEIEVSLA----- 959
Query: 2034 RDLPGVQNLRRKHRRIDTELASHEPQVSLVKLKGEELLRSAAEAGVGED-QIKKRMEDLE 1858
D P +++ R+ D A + ++ G G+ +I+ R +
Sbjct: 960 -DEPSPEHVAAFRRKFDKLEADMKTNGGTQLKHINDIANDLISEGHGQSRKIEVRQHKIN 1018
Query: 1857 QSWGQIRDLTGNRHQRLDESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLL 1678
W + L R RL+ +E F E WM K + L D ++ +Q L
Sbjct: 1019 AMWDNLERLRKQRGVRLEATERVADFDTTCESAREWMLSKFEQL--DRNPNDVKSLQNL- 1075
Query: 1677 KKHDTFQVDLELHKQRVADLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRL 1498
+ DL+ + ++A L + + A I+++ +LRA ++ A+ ++
Sbjct: 1076 ------ERDLKPLEDKIAALEKLAAAVKKDHPEEAAAIERKIAELRALHADLLRRAQEKM 1129
Query: 1497 AKLRDNSAYLQFMWKCDVVESWIAEKEQQVRSEDFGR-DLSSVQILLTKQEAFDAGLNAF 1321
F + WI EK ++V ED D++ + LL K +
Sbjct: 1130 LLAEQTQGKEMFESALRDMIGWI-EKTRKVMMEDVHPVDVAEAEELLKKHYELGEQIKDK 1188
Query: 1320 EHEGIQRITELKDQLVSSEHQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQ 1141
++E ++ EL +L+ +++P + K V ++ QNL++ + R Q
Sbjct: 1189 KYE-VEYCQELGRRLL----ERNPRMSK----VEEQLQNLVSEMASLRDLYRRRDTILKQ 1239
Query: 1140 IEELYLAFAKKASTFNSWFENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFR 961
+L L F +++ ++ + E L +S+E + L H + + L + E
Sbjct: 1240 QLDLQL-FNRESERIDAATKGHEAFLEFDNLGDSVESVENLLKRHRDLEAKLDAQEARLE 1298
Query: 960 QL-QDLDRRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLR 784
+ D IK+ + D L ++R +R+++L + QE +R
Sbjct: 1299 AFSRTADDMIKAQHADSAYIEQRRRDVLARR-EAVRRAAAQRKKQLEASLEYQE----MR 1353
Query: 783 REFAKLANAFH--AWLTNTRQEMMEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAM 610
RE ++ + A L + + A + +L E EI AN+ +++QI +G
Sbjct: 1354 READEVVGWMYEKAKLVMSGDDSALAPSAIPHRLLKHEAFEAEIIANEPRIQQINSEGDG 1413
Query: 609 LERNLILDNRYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMM 430
L ++ E + W L + L Q + + E+A + M
Sbjct: 1414 LVSKKHYESPNVEKIVRQVNAQWGDLKKQVWNKGLRLRQAADQKGLDRILEDAHAKLDEM 1473
Query: 429 FKHFDKEKTGRLDHQQFKSCLR 364
+ + G LD + K L+
Sbjct: 1474 QTALNSKDQG-LDLRSVKDLLQ 1494
Score = 137 bits (346), Expect = 3e-30
Identities = 150/735 (20%), Positives = 298/735 (40%), Gaps = 13/735 (1%)
Frame = -1
Query: 2523 ARLKALNDQWDLLVKTTTEKSYRLKEANKQKSFMAAVKDLEFWLGEVEILLQSEDYGKDL 2344
A+L ++ + + ++ +L++ ++ A ++D WL V+++L+ ++G+
Sbjct: 395 AQLDYAENERQVAIIAELQRQEKLEQLAQRFHKKAKLRDS--WLRSVQVVLEEMEHGRSA 452
Query: 2343 ASVENLLKKHSLLEADIVAHQDRVGEMNEQADSLLENDQFQGQQIAERRKLIADRYDGVK 2164
+ VE LKK + DI+A +DR + + L + ++ + I DR+ +
Sbjct: 453 SQVEKTLKKQQAISTDILAREDRFKMLTAMCNELCTEKYHESDKVRGMEREIIDRWTQLL 512
Query: 2163 KMATDRRDKLSKALNVHQFFRDIDDEESWIKEKKLLVSSDDYGRDLPGVQNLRRKHRRID 1984
+ R+ L ++ RDID + + + V + D G+ L GV++L KH +D
Sbjct: 513 TLLEQRKRALMSLNDLMSLLRDIDTLSNELYSLEPAVRNRDVGKHLIGVEDLLGKHDLLD 572
Query: 1983 TELASHEPQVSLVKLKGEELLRSAAEAGVGEDQIKKRMEDLEQSWGQIRDLTGNRHQRLD 1804
++ +H +S + +R E D ++++++++ + + +L +R L+
Sbjct: 573 AQINAHGSLLSKLSQSANNYIRHKEEQ---FDVLQRKLDEVTAQYNTLVELCRSRRLGLE 629
Query: 1803 ESEAFQAFLGDVEEEEAWMNEKQQILGSDNFGENMAGVQGLLKKHDTFQVDLELHKQRVA 1624
+ + F+ D EEE AW+ EK+++ + +++ V + +++++ H R
Sbjct: 630 RARSLFQFVQDHEEEMAWLAEKEKLCTTALNSGDISAVPQTTLLYKNVEMEMQTHWARSK 689
Query: 1623 DLINKGDTLIHNGNHHAPHIKQRCDQLRARLIEIESMAEGRLAKLRDNSAYLQFMWKCDV 1444
+I G+ L+ NG I++R Q+ R + + L + Q+ +
Sbjct: 690 GMIAGGERLVQNG-QSKEDIQRRLTQMNHRWERLRVAVDALGNWLSEARHAQQYFQDANE 748
Query: 1443 VESWIAEKEQQVRSEDFGRDLSSVQILLTKQEAFDAGLNAFEHEGIQRITELKDQLVSSE 1264
ESWI EK V+S+D GRD + + LL + + + A++ + I R+ E++ QL +S
Sbjct: 749 AESWIREKMPLVKSDDLGRDEGAAESLLQRHARLEEEIRAYKSD-ISRLEEMQSQLANSA 807
Query: 1263 -HQQSPAIEKRHTNVIQRWQNLLAHSEARRXXXXXXXXXXXQIEELYLAF--AKKASTFN 1093
H + + + T + Q ++++ +E+ + A K
Sbjct: 808 FHTATTSQSVQETEEVNVPQVEMSYNYEGNGMRVSKGEVLALLEKSTPEWWRALKRDGTE 867
Query: 1092 SWF----------ENAEEDLTDPVRCNSLEEIRALRDAHGEFQRSLSSAEEDFRQLQDLD 943
+ E T +LE + Q +S+ + ++L D+
Sbjct: 868 GYVPANYCKIVPGETVTVTQTTQKTTTTLEGNETKSSVVADRQHKISNDYRELKRLADVR 927
Query: 942 RRIKSFNVGPNPYTWFTMDALEDTWRNLQRIIKEREQELAREHQRQEENDKLRREFAKLA 763
RR+ S N+ F + E +R KE E LA E E RR+F KL
Sbjct: 928 RRLLSDNI---KLLRFYRECDE-----FERWAKEIEVSLADE-PSPEHVAAFRRKFDKL- 977
Query: 762 NAFHAWLTNTRQEMMEAGGTLEEQLDAVERKAKEIKANKGQLRQIEEKGAMLERNLILDN 583
+M GGT + ++ + I GQ R+IE +
Sbjct: 978 ----------EADMKTNGGTQLKHINDIANDL--ISEGHGQSRKIEVR------------ 1013
Query: 582 RYTEHSTVGIAQAWDQLDQLAMRMQHNLEQQIQARNQSGVSEEALREFSMMFKHFDKEKT 403
+H I WD L++L + LE + + E A F+ D+
Sbjct: 1014 ---QHK---INAMWDNLERLRKQRGVRLEATERVADFDTTCESAREWMLSKFEQLDRNPN 1067
Query: 402 GRLDHQQFKSCLRAL 358
Q + L+ L
Sbjct: 1068 DVKSLQNLERDLKPL 1082