Homology by BLASTX
BLASTX 2.2.4 [Aug-26-2002]
Query= R06A4_4
(2652 letters)
Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
1,967,186 sequences; 661,712,633 total letters
Score E
Sequences producing significant alignments: (bits) Value
gi|17535481|ref|NP_496987.1| IMportin Beta (imb-2) [Caenorhabdit... 1670 0.0
gi|39582715|emb|CAE65921.1| Hypothetical protein CBG11089 [Caeno... 1556 0.0
gi|23510379|ref|NP_002261.2| transportin 1; karyopherin (importi... 859 0.0
gi|1613834|gb|AAC50723.1| transportin [Homo sapiens] 858 0.0
gi|30520133|ref|NP_848831.1| transportin 1; karyopherin (importi... 857 0.0
gi|26325884|dbj|BAC26696.1| unnamed protein product [Mus musculus] 856 0.0
gi|1622943|gb|AAB68948.1| MIP [Homo sapiens] 856 0.0
gi|3293344|gb|AAC25709.1| transportin; TRN [Xenopus laevis] 841 0.0
gi|21703780|ref|NP_663365.1| karyopherin (importin) beta 2b [Mus... 840 0.0
gi|48675813|ref|NP_038461.2| transportin 2 (importin 3, karyophe... 839 0.0
gi|34851417|ref|XP_222478.2| similar to karyopherin (importin) b... 839 0.0
gi|48095991|ref|XP_392373.1| similar to transportin 1; karyopher... 837 0.0
gi|5107636|pdb|1QBK|B Chain B, Structure Of The Karyopherin Beta... 833 0.0
gi|31214900|ref|XP_315921.1| ENSANGP00000013476 [Anopheles gambi... 830 0.0
gi|45504418|sp|O14787|TNP2_HUMAN Transportin 2 (Karyopherin beta... 830 0.0
gi|2440004|gb|AAB71349.1| karyopherin beta2b homolog [Homo sapiens] 829 0.0
gi|2589204|gb|AAB83973.1| transportin2 [Homo sapiens] 825 0.0
gi|17535479|ref|NP_496988.1| IMportin Beta (46.8 kD) (imb-2) [Ca... 822 0.0
gi|17137558|ref|NP_477368.1| CG7398-PA [Drosophila melanogaster]... 811 0.0
gi|27819795|gb|AAO24946.1| RE59670p [Drosophila melanogaster] 809 0.0
gi|47223870|emb|CAG06047.1| unnamed protein product [Tetraodon n... 807 0.0
gi|3293342|gb|AAC25708.1| transportin; TRN [Drosophila melanogas... 803 0.0
gi|34853468|ref|XP_219500.2| similar to karyopherin beta 2; impo... 791 0.0
gi|50761696|ref|XP_424806.1| PREDICTED: similar to transportin 1... 692 0.0
gi|24659272|ref|NP_648038.1| CG8219-PA [Drosophila melanogaster]... 690 0.0
gi|21429774|gb|AAM50565.1| AT21921p [Drosophila melanogaster] 688 0.0
gi|21618743|gb|AAH31571.1| Tnpo1 protein [Mus musculus] 652 0.0
gi|20151549|gb|AAM11134.1| LD12333p [Drosophila melanogaster] 647 0.0
gi|50258039|gb|EAL20733.1| hypothetical protein CNBE0960 [Crypto... 615 e-174
gi|30679820|ref|NP_179287.2| importin beta-2 subunit family prot... 602 e-170
gi|49075976|ref|XP_402012.1| hypothetical protein UM04397.1 [Ust... 600 e-170
gi|23954104|emb|CAC80068.1| transportin [Arabidopsis thaliana] 598 e-169
gi|26325714|dbj|BAC26611.1| unnamed protein product [Mus musculus] 586 e-165
gi|38567827|emb|CAE05776.2| OSJNBb0020J19.5 [Oryza sativa (japon... 580 e-164
gi|19115297|ref|NP_594385.1| putative importin beta-2 subunit (t... 567 e-160
gi|25411759|pir||C84546 probable transportin [imported] - Arabid... 543 e-153
gi|47212752|emb|CAF90598.1| unnamed protein product [Tetraodon n... 499 e-139
gi|50554935|ref|XP_504876.1| hypothetical protein [Yarrowia lipo... 491 e-137
gi|49085962|ref|XP_405063.1| hypothetical protein AN0926.2 [Aspe... 491 e-137
gi|47219830|emb|CAF97100.1| unnamed protein product [Tetraodon n... 489 e-136
gi|46109944|ref|XP_382030.1| hypothetical protein FG01854.1 [Gib... 478 e-133
gi|32404758|ref|XP_322992.1| related to IMPORTIN BETA-2 SUBUNIT ... 473 e-131
gi|50418807|ref|XP_457924.1| unnamed protein product [Debaryomyc... 447 e-124
gi|46436514|gb|EAK95875.1| hypothetical protein CaO19.3556 [Cand... 439 e-121
gi|46436579|gb|EAK95939.1| hypothetical protein CaO19.11040 [Can... 385 e-105
gi|50290025|ref|XP_447444.1| unnamed protein product [Candida gl... 363 1e-98
gi|24817248|emb|CAD56216.1| transportin-like protein [Cicer arie... 355 2e-96
gi|6319491|ref|NP_009573.1| Transportin, cytosolic karyopherin b... 348 4e-94
gi|45190822|ref|NP_985076.1| AER219Cp [Eremothecium gossypii] >g... 328 4e-88
gi|50304865|ref|XP_452388.1| unnamed protein product [Kluyveromy... 327 9e-88
gi|15227336|ref|NP_179288.1| importin beta-2 subunit family prot... 300 2e-79
gi|38109547|gb|EAA55401.1| hypothetical protein MG09208.4 [Magna... 291 7e-77
gi|23954314|emb|CAC80069.1| transportin [Oryza sativa] 282 3e-74
gi|21428464|gb|AAM49892.1| LD19058p [Drosophila melanogaster] 281 6e-74
gi|46228841|gb|EAK89711.1| importin beta like ARM repeat alpha s... 256 2e-66
gi|23612355|ref|NP_703935.1| transportin [Plasmodium falciparum ... 186 2e-45
gi|17297993|dbj|BAB78507.1| transportin [Plasmodium falciparum] 186 2e-45
gi|23490398|gb|EAA22187.1| transportin-related [Plasmodium yoeli... 183 2e-44
gi|50405179|ref|YP_054271.1| Importin, putative [Paramecium tetr... 159 4e-37
gi|32140354|gb|AAP69669.1| transportin [Bos taurus] 146 3e-33
gi|50761694|ref|XP_424805.1| PREDICTED: similar to transportin 1... 141 7e-32
gi|31234324|ref|XP_319040.1| ENSANGP00000013260 [Anopheles gambi... 97 2e-18
gi|15238758|ref|NP_200160.1| importin beta-2, putative [Arabidop... 91 2e-16
gi|26449534|dbj|BAC41893.1| putative importin beta [Arabidopsis ... 91 2e-16
gi|47200030|emb|CAF87397.1| unnamed protein product [Tetraodon n... 88 1e-15
gi|3983665|dbj|BAA34862.1| importin-beta2 [Oryza sativa (japonic... 87 3e-15
gi|19115145|ref|NP_594233.1| importin beta-1 subunit [Schizosacc... 84 2e-14
gi|22328982|ref|NP_194494.2| importin beta-2 subunit family prot... 81 1e-13
gi|7487507|pir||T05869 hypothetical protein T29A15.130 - Arabido... 80 3e-13
gi|27682639|ref|XP_219796.1| similar to hypothetical protein [Ra... 77 2e-12
gi|34902110|ref|NP_912401.1| unknown protein [Oryza sativa (japo... 77 2e-12
gi|3983663|dbj|BAA34861.1| importin-beta1 [Oryza sativa (japonic... 76 4e-12
gi|45331213|ref|NP_036548.1| RAN binding protein 6 [Homo sapiens] 74 2e-11
gi|50400810|sp|O60518|RBP6_HUMAN Ran-binding protein 6 (RanBP6) ... 74 2e-11
gi|31873312|emb|CAD97647.1| hypothetical protein [Homo sapiens] 74 2e-11
gi|23954312|emb|CAC79691.1| Importin beta-like protein [Oryza sa... 74 2e-11
gi|48097940|ref|XP_393927.1| similar to ENSANGP00000013260 [Apis... 74 2e-11
gi|17137782|ref|NP_477496.1| CG2637-PA [Drosophila melanogaster]... 74 2e-11
gi|2137601|pir||S66288 nuclear pore-targeting complex protein, 9... 74 2e-11
gi|28381019|gb|AAO41476.1| GH07384p [Drosophila melanogaster] 73 3e-11
gi|17737759|ref|NP_524226.1| CG1059-PA [Drosophila melanogaster]... 73 3e-11
gi|30931411|gb|AAH52711.1| Karyopherin (importin) beta 1 [Mus mu... 73 3e-11
gi|31543051|ref|NP_032405.2| karyopherin (importin) beta 1; impo... 73 3e-11
gi|50550515|ref|XP_502730.1| hypothetical protein [Yarrowia lipo... 71 1e-10
gi|46435252|gb|EAK94638.1| hypothetical protein CaO19.11165 [Can... 71 1e-10
gi|19923142|ref|NP_002256.2| karyopherin beta 1; nuclear factor ... 71 2e-10
gi|5107666|pdb|1QGK|A Chain A, Structure Of Importin Beta Bound ... 70 3e-10
gi|6048198|emb|CAA05691.2| importin beta [Drosophila melanogaster] 70 3e-10
gi|27803065|emb|CAD60768.1| unnamed protein product [Podospora a... 68 1e-09
gi|50303691|ref|XP_451788.1| unnamed protein product [Kluyveromy... 67 3e-09
gi|49096788|ref|XP_409854.1| hypothetical protein AN5717.2 [Aspe... 66 4e-09
gi|39584602|emb|CAE72355.1| Hypothetical protein CBG19502 [Caeno... 66 5e-09
gi|50257361|gb|EAL20070.1| hypothetical protein CNBF3960 [Crypto... 65 6e-09
gi|50556022|ref|XP_505419.1| hypothetical protein [Yarrowia lipo... 65 1e-08
gi|50295072|ref|XP_449947.1| unnamed protein product [Candida gl... 60 2e-07
gi|46436578|gb|EAK95938.1| hypothetical protein CaO19.11039 [Can... 60 3e-07
gi|15241189|ref|NP_197483.1| PBS lyase HEAT-like repeat-containi... 60 4e-07
gi|46135877|ref|XP_389630.1| conserved hypothetical protein [Gib... 60 4e-07
gi|26451837|dbj|BAC43011.1| unknown protein [Arabidopsis thaliana] 59 5e-07
gi|49085916|ref|XP_405043.1| hypothetical protein AN0906.2 [Aspe... 58 1e-06
gi|50419275|ref|XP_458161.1| unnamed protein product [Debaryomyc... 57 3e-06
gi|32410049|ref|XP_325505.1| hypothetical protein [Neurospora cr... 56 4e-06
gi|39589315|emb|CAE74344.1| Hypothetical protein CBG22062 [Caeno... 56 5e-06
gi|46439263|gb|EAK98583.1| hypothetical protein CaO19.12551 [Can... 55 1e-05
gi|38566891|emb|CAE76196.1| probable KAP95 protein [Neurospora c... 54 1e-05
gi|32417446|ref|XP_329201.1| hypothetical protein [Neurospora cr... 54 1e-05
gi|13097471|gb|AAH03469.1| Ipo4 protein [Mus musculus] >gnl|BL_O... 54 2e-05
gi|19745156|ref|NP_077229.4| RANBP4; EST AA409693; importin 4a [... 54 2e-05
gi|17506191|ref|NP_490715.1| IMportin Beta (122.0 kD) (imb-3Co) ... 53 3e-05
gi|19033563|gb|AAL83632.1| putative Ran binding protein [Oryza s... 52 7e-05
gi|38105675|gb|EAA52073.1| hypothetical protein MG03668.4 [Magna... 52 7e-05
gi|34898648|ref|NP_910670.1| similar to RANBP9 isoform 1 [Oryza ... 51 1e-04
gi|50305745|ref|XP_452833.1| unnamed protein product [Kluyveromy... 51 1e-04
gi|34874165|ref|XP_214199.2| similar to RANBP4 [Rattus norvegicus] 50 4e-04
gi|45200748|ref|NP_986318.1| AGL349Cp [Eremothecium gossypii] >g... 50 4e-04
gi|46229495|gb|EAK90313.1| importin/karyopherin, transcripts ide... 49 5e-04
gi|47208668|emb|CAF93535.1| unnamed protein product [Tetraodon n... 49 5e-04
gi|39580853|emb|CAE73114.1| Hypothetical protein CBG20495 [Caeno... 48 0.001
gi|47213555|emb|CAF91829.1| unnamed protein product [Tetraodon n... 48 0.001
gi|6323968|ref|NP_014039.1| Karyopherin/importin that interacts ... 47 0.002
gi|4246|emb|CAA77639.1| PSE-1 [Saccharomyces cerevisiae] >gnl|BL... 47 0.002
gi|6714425|gb|AAF26113.1| putative exportin1 (XPO1) protein [Ara... 47 0.002
gi|30678764|ref|NP_566193.2| exportin 1, putative [Arabidopsis t... 47 0.002
gi|14250864|emb|CAC39223.1| exportin 1b [Arabidopsis thaliana] 47 0.002
gi|49068290|ref|XP_398434.1| hypothetical protein UM00819.1 [Ust... 46 0.005
gi|31199733|ref|XP_308814.1| ENSANGP00000021619 [Anopheles gambi... 45 0.007
gi|13277562|gb|AAH03690.1| IPO4 protein [Homo sapiens] >gnl|BL_O... 45 0.007
gi|28207883|emb|CAD62595.1| unnamed protein product [Homo sapiens] 45 0.007
gi|23479492|gb|EAA16307.1| importin beta-1 subunit [Plasmodium y... 45 0.007
gi|15237894|ref|NP_197204.1| exportin1 (XPO1) [Arabidopsis thali... 45 0.009
gi|50418405|ref|XP_457778.1| unnamed protein product [Debaryomyc... 45 0.009
gi|25149756|ref|NP_491477.2| IMportin Beta (98.8 kD) (imb-1) [Ca... 44 0.015
gi|41149051|ref|XP_036708.8| KIAA0368 protein [Homo sapiens] 44 0.026
gi|2224677|dbj|BAA20823.1| KIAA0368 [Homo sapiens] 44 0.026
gi|50552890|ref|XP_503855.1| hypothetical protein [Yarrowia lipo... 43 0.034
gi|18874099|ref|NP_078934.2| importin 4 [Homo sapiens] >gnl|BL_O... 43 0.045
gi|10439989|dbj|BAB15616.1| unnamed protein product [Homo sapiens] 43 0.045
gi|50420219|ref|XP_458642.1| unnamed protein product [Debaryomyc... 43 0.045
gi|32417562|ref|XP_329259.1| hypothetical protein [Neurospora cr... 43 0.045
gi|11862948|dbj|BAB19329.1| hypothetical protein [Oryza sativa (... 43 0.045
gi|34393573|dbj|BAC83171.1| putative karyopherin-beta 3 variant ... 42 0.100
gi|31204951|ref|XP_311424.1| ENSANGP00000018477 [Anopheles gambi... 41 0.13
gi|46110703|ref|XP_382409.1| hypothetical protein FG02233.1 [Gib... 41 0.17
gi|39591891|emb|CAE71469.1| Hypothetical protein CBG18387 [Caeno... 41 0.17
gi|17552816|ref|NP_499306.1| putative protein of eukaryotic orig... 40 0.22
gi|7658229|gb|AAF66097.1| Crm1p [Candida albicans] >gnl|BL_ORD_I... 40 0.29
gi|49073198|ref|XP_400831.1| hypothetical protein UM03216.1 [Ust... 40 0.29
gi|50762025|ref|XP_424915.1| PREDICTED: similar to Expressed seq... 40 0.29
gi|50309331|ref|XP_454672.1| unnamed protein product [Kluyveromy... 40 0.29
gi|38344992|emb|CAE01598.2| OSJNBa0008A08.6 [Oryza sativa (japon... 40 0.38
gi|22330143|ref|NP_175425.2| target of rapamycin protein (TOR) [... 40 0.38
gi|29247556|gb|EAA39115.1| GLP_305_41443_37988 [Giardia lamblia ... 39 0.49
gi|50425791|ref|XP_461492.1| unnamed protein product [Debaryomyc... 39 0.49
gi|23487852|gb|EAA21162.1| putative impotin alpha 1b [Plasmodium... 39 0.49
gi|50304405|ref|XP_452152.1| unnamed protein product [Kluyveromy... 39 0.49
gi|50302959|ref|XP_451417.1| unnamed protein product [Kluyveromy... 39 0.65
gi|48102316|ref|XP_395332.1| similar to ENSANGP00000018477 [Apis... 39 0.65
gi|28569600|gb|AAO43977.1| Tor [Dictyostelium discoideum] 39 0.84
gi|47210546|emb|CAF90685.1| unnamed protein product [Tetraodon n... 38 1.4
gi|468739|emb|CAA52849.1| TOR1 [Saccharomyces cerevisiae] 38 1.4
gi|50555652|ref|XP_505234.1| hypothetical protein [Yarrowia lipo... 38 1.4
gi|46440278|gb|EAK99586.1| hypothetical protein CaO19.2489 [Cand... 37 1.9
gi|38105524|gb|EAA51942.1| hypothetical protein MG03537.4 [Magna... 37 1.9
gi|40641621|emb|CAE55861.1| Exportin 1 [Chironomus tentans] 37 1.9
gi|6322526|ref|NP_012600.1| Involved in cell cycle signaling and... 37 2.5
gi|408956|gb|AAB66881.1| mutant drr1-1 protein [Saccharomyces ce... 37 2.5
gi|15231619|ref|NP_191461.1| importin beta-2 subunit family prot... 37 2.5
gi|46102924|ref|ZP_00197999.1| COG0799: Uncharacterized homolog ... 37 2.5
gi|19263497|gb|AAH25400.1| MGC40042 protein [Homo sapiens] 37 3.2
gi|46329786|gb|AAH68908.1| MGC83107 protein [Xenopus laevis] 37 3.2
gi|19113521|ref|NP_596729.1| putative importin beta-4 subunit [S... 37 3.2
gi|50555395|ref|XP_505106.1| hypothetical protein [Yarrowia lipo... 37 3.2
gi|50257931|gb|EAL20629.1| hypothetical protein CNBE3370 [Crypto... 37 3.2
gi|15218932|ref|NP_176194.1| expressed protein [Arabidopsis thal... 37 3.2
gi|48120807|ref|XP_396469.1| similar to Xpo1 protein [Apis melli... 37 3.2
gi|42662475|ref|XP_376013.1| similar to meiosis defective 1 [Hom... 37 3.2
gi|45506172|ref|ZP_00158531.1| hypothetical protein Avar471301 [... 36 4.2
gi|47125110|gb|AAH70550.1| Xpo1 protein [Xenopus laevis] 36 4.2
gi|4507943|ref|NP_003391.1| exportin 1; Exportin-1 (required for... 36 4.2
gi|38604071|ref|NP_598775.2| exportin 1, CRM1 homolog [Mus muscu... 36 4.2
gi|29789299|ref|NP_445942.1| exportin 1 (CRM1, yeast, homolog) [... 36 4.2
gi|5690335|gb|AAD47043.1| CRM1/XPO1 protein [Xenopus laevis] 36 4.2
gi|4689038|emb|CAB41422.1| CRM1 protein [Rattus norvegicus] 36 4.2
gi|15231992|ref|NP_187508.1| importin beta-2 subunit family prot... 36 4.2
gi|23612892|ref|NP_704431.1| importin alpha, putative [Plasmodiu... 36 4.2
gi|23485509|gb|EAA20453.1| axoneme central apparatus protein [Pl... 36 4.2
gi|50738244|ref|XP_419270.1| PREDICTED: similar to Xpo1 protein ... 36 4.2
gi|15126703|gb|AAH12276.1| Xpo1 protein [Mus musculus] >gnl|BL_O... 36 4.2
gi|45200799|ref|NP_986369.1| AGL298Cp [Eremothecium gossypii] >g... 36 5.5
gi|232040|sp|P29551|EF3_PNECA Elongation factor 3 (EF-3) >gnl|BL... 36 5.5
gi|46123013|ref|XP_386060.1| hypothetical protein FG05884.1 [Gib... 36 5.5
gi|50758404|ref|XP_415906.1| PREDICTED: similar to MGC53988 prot... 36 5.5
gi|49097034|ref|XP_409977.1| hypothetical protein AN5840.2 [Aspe... 36 5.5
gi|49096408|ref|XP_409664.1| hypothetical protein AN5527.2 [Aspe... 35 7.1
gi|6320956|ref|NP_011035.1| Karyopherin beta, mediates nuclear i... 35 7.1
gi|49069864|ref|XP_399221.1| hypothetical protein UM01606.1 [Ust... 35 7.1
gi|50256966|gb|EAL19684.1| hypothetical protein CNBG3120 [Crypto... 35 7.1
gi|31197643|ref|XP_307769.1| ENSANGP00000012932 [Anopheles gambi... 35 7.1
gi|23272803|gb|AAH35720.1| MGC40042 protein [Homo sapiens] 35 9.3
gi|50761577|ref|XP_429135.1| PREDICTED: similar to Ran binding p... 35 9.3
gi|50740580|ref|XP_419500.1| PREDICTED: similar to RANBP21 [Gall... 35 9.3
gi|18396241|ref|NP_564273.1| expressed protein [Arabidopsis thal... 35 9.3
gi|8778871|gb|AAF79870.1| T7N9.27 [Arabidopsis thaliana] 35 9.3
gi|32410355|ref|XP_325658.1| hypothetical protein [Neurospora cr... 35 9.3
gi|9802548|gb|AAF99750.1| F17L21.1 [Arabidopsis thaliana] 35 9.3
>gi|17535481|ref|NP_496987.1| IMportin Beta (imb-2) [Caenorhabditis
elegans]
gi|7506339|pir||T23948 hypothetical protein R06A4.4a - Caenorhabditis
elegans
gi|3878860|emb|CAB05586.1| C. elegans IMB-2 protein (corresponding
sequence R06A4.4a) [Caenorhabditis elegans]
Length = 883
Score = 1670 bits (4326), Expect = 0.0
Identities = 837/883 (94%), Positives = 837/883 (94%)
Frame = +1
Query: 1 MAFQPDQHELEQVIQLLQHAHSTXXXXXXXXXXXXXXXXEHQKFCCYLVYILSDMKEMID 180
MAFQPDQHELEQVIQLLQHAHST EHQKFCCYLVYILSDMKEMID
Sbjct: 1 MAFQPDQHELEQVIQLLQHAHSTDRDVQRNVQVQLVQLNEHQKFCCYLVYILSDMKEMID 60
Query: 181 ATSRSLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGDQEPLIRATVGIIVTTIVMEE 360
ATSRSLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGDQEPLIRATVGIIVTTIVMEE
Sbjct: 61 ATSRSLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGDQEPLIRATVGIIVTTIVMEE 120
Query: 361 NMCDWPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYESEFLRPIMPKLLVFYEH 540
NMCDWPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYESEFLRPIMPKLLVFYEH
Sbjct: 121 NMCDWPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYESEFLRPIMPKLLVFYEH 180
Query: 541 HAAKMRALAMNCVNCILMVNNDPIDFAIDQFLTSLFARHNDNDEEVQKQLCRSLTLLLDT 720
HAAKMRALAMNCVNCILMVNNDPIDFAIDQFLTSLFARHNDNDEEVQKQLCRSLTLLLDT
Sbjct: 181 HAAKMRALAMNCVNCILMVNNDPIDFAIDQFLTSLFARHNDNDEEVQKQLCRSLTLLLDT 240
Query: 721 HIEKMMPHLPNVIEYIIKKTQDHNESIALEACEFWLSIAENSDICRTMVLPHLDKLIPVL 900
HIEKMMPHLPNVIEYIIKKTQDHNESIALEACEFWLSIAENSDICRTMVLPHLDKLIPVL
Sbjct: 241 HIEKMMPHLPNVIEYIIKKTQDHNESIALEACEFWLSIAENSDICRTMVLPHLDKLIPVL 300
Query: 901 LGSMRYSETDPALKANDEDSSVPDREEDIKPRFHKSKQHGLGGLVESXXXXXXXXXXXXX 1080
LGSMRYSETDPALKANDEDSSVPDREEDIKPRFHKSKQHGLGGLVES
Sbjct: 301 LGSMRYSETDPALKANDEDSSVPDREEDIKPRFHKSKQHGLGGLVESDDEEDEDDDDDGG 360
Query: 1081 XXWNIRRCSAASLDVLASIFGXXXXXXXXXXXXXXXMNDNWLVKESGILALGAIAEGCMD 1260
WNIRRCSAASLDVLASIFG MNDNWLVKESGILALGAIAEGCMD
Sbjct: 361 GDWNIRRCSAASLDVLASIFGKDLLDKLFPLLKDTLMNDNWLVKESGILALGAIAEGCMD 420
Query: 1261 GVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHIASDENFRQQFFKDVLANLLRC 1440
GVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHIASDENFRQQFFKDVLANLLRC
Sbjct: 421 GVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHIASDENFRQQFFKDVLANLLRC 480
Query: 1441 SLDGNKKVQEAACSAFATLEEEAGEQLIPFLGEILDQLVKAFQCYQAKNLLILYDAIGTL 1620
SLDGNKKVQEAACSAFATLEEEAGEQLIPFLGEILDQLVKAFQCYQAKNLLILYDAIGTL
Sbjct: 481 SLDGNKKVQEAACSAFATLEEEAGEQLIPFLGEILDQLVKAFQCYQAKNLLILYDAIGTL 540
Query: 1621 ANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISAIVSAMGQSFLPYIQPV 1800
ANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISAIVSAMGQSFLPYIQPV
Sbjct: 541 ANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISAIVSAMGQSFLPYIQPV 600
Query: 1801 FTRCCSLIEKCVQQNQQHIMAPDQVEAPETDFIIVALDLLSGLAESLPEHMDPLVANSKL 1980
FTRCCSLIEKCVQQNQQHIMAPDQVEAPETDFIIVALDLLSGLAESLPEHMDPLVANSKL
Sbjct: 601 FTRCCSLIEKCVQQNQQHIMAPDQVEAPETDFIIVALDLLSGLAESLPEHMDPLVANSKL 660
Query: 1981 VELMLFCSLDVTPDVRQSCFALLGDLTKACPERVLPQSSNFIFFLAQNLDPSKISVCNNA 2160
VELMLFCSLDVTPDVRQSCFALLGDLTKACPERVLPQSSNFIFFLAQNLDPSKISVCNNA
Sbjct: 661 VELMLFCSLDVTPDVRQSCFALLGDLTKACPERVLPQSSNFIFFLAQNLDPSKISVCNNA 720
Query: 2161 IWALGELALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLLENTAITIGRLGQCCGEELA 2340
IWALGELALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLLENTAITIGRLGQCCGEELA
Sbjct: 721 IWALGELALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLLENTAITIGRLGQCCGEELA 780
Query: 2341 PHISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGVLNDFIFWCDAIASWTVPTD 2520
PHISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGVLNDFIFWCDAIASWTVPTD
Sbjct: 781 PHISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGVLNDFIFWCDAIASWTVPTD 840
Query: 2521 SLRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAFYQI 2649
SLRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAFYQI
Sbjct: 841 SLRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAFYQI 883
>gi|39582715|emb|CAE65921.1| Hypothetical protein CBG11089
[Caenorhabditis briggsae]
Length = 879
Score = 1556 bits (4029), Expect = 0.0
Identities = 771/880 (87%), Positives = 807/880 (91%)
Frame = +1
Query: 1 MAFQPDQHELEQVIQLLQHAHSTXXXXXXXXXXXXXXXXEHQKFCCYLVYILSDMKEMID 180
M FQPDQHEL+QVIQLL+HAHS EHQ+FCCYLV+ILS+MK ID
Sbjct: 1 MTFQPDQHELQQVIQLLRHAHSMDREVQRTVQVQLVQLNEHQQFCCYLVFILSEMKGQID 60
Query: 181 ATSRSLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGDQEPLIRATVGIIVTTIVMEE 360
+TSRSLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGD EPLIRATVGIIVTTIVMEE
Sbjct: 61 STSRSLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGDAEPLIRATVGIIVTTIVMEE 120
Query: 361 NMCDWPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYESEFLRPIMPKLLVFYEH 540
NMCDWPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYE EFLRPIMPKLL+FYEH
Sbjct: 121 NMCDWPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYECEFLRPIMPKLLIFYEH 180
Query: 541 HAAKMRALAMNCVNCILMVNNDPIDFAIDQFLTSLFARHNDNDEEVQKQLCRSLTLLLDT 720
H AKMRALAMN VNCILMVNNDPIDFAID+FLT+LFARHNDNDEEVQKQLCRSLTLLLDT
Sbjct: 181 HNAKMRALAMNSVNCILMVNNDPIDFAIDEFLTALFARHNDNDEEVQKQLCRSLTLLLDT 240
Query: 721 HIEKMMPHLPNVIEYIIKKTQDHNESIALEACEFWLSIAENSDICRTMVLPHLDKLIPVL 900
HIEKMMPHLPNVIEYIIKKTQDHNESIALEACEFWLSIAEN++ICRTMVLPHLDKLIPVL
Sbjct: 241 HIEKMMPHLPNVIEYIIKKTQDHNESIALEACEFWLSIAENNEICRTMVLPHLDKLIPVL 300
Query: 901 LGSMRYSETDPALKANDEDSSVPDREEDIKPRFHKSKQHGLGGLVESXXXXXXXXXXXXX 1080
LGSMRYSETDPALKAN+EDSSVPDREEDIKPRFHKSKQHGLGG+++S
Sbjct: 301 LGSMRYSETDPALKANEEDSSVPDREEDIKPRFHKSKQHGLGGIMDSDDEDEDDDDDDGG 360
Query: 1081 XXWNIRRCSAASLDVLASIFGXXXXXXXXXXXXXXXMNDNWLVKESGILALGAIAEGCMD 1260
WNIRRC+AASLDVLASIFG MNDNWLVKESGILALGAIAEGCMD
Sbjct: 361 GDWNIRRCAAASLDVLASIFGKDLLDKLFPLLKDTLMNDNWLVKESGILALGAIAEGCMD 420
Query: 1261 GVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHIASDENFRQQFFKDVLANLLRC 1440
GVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHI SDENFRQ FFKDVLANLLRC
Sbjct: 421 GVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHIVSDENFRQNFFKDVLANLLRC 480
Query: 1441 SLDGNKKVQEAACSAFATLEEEAGEQLIPFLGEILDQLVKAFQCYQAKNLLILYDAIGTL 1620
SLD NKKVQEAACSAFATLEEEAGEQLIPFLGEIL+QLVKAFQCYQAKNLLILYDAIGTL
Sbjct: 481 SLDSNKKVQEAACSAFATLEEEAGEQLIPFLGEILEQLVKAFQCYQAKNLLILYDAIGTL 540
Query: 1621 ANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISAIVSAMGQSFLPYIQPV 1800
ANSVG+ALSHP YVQMLMPPLMEKWERL +EDKELFPLLECISAIVSAMGQSF+PYIQPV
Sbjct: 541 ANSVGEALSHPHYVQMLMPPLMEKWERL-NEDKELFPLLECISAIVSAMGQSFIPYIQPV 599
Query: 1801 FTRCCSLIEKCVQQNQQHIMAPDQVEAPETDFIIVALDLLSGLAESLPEHMDPLVANSKL 1980
FTRCC+LIEKCVQQNQQH+M+P+ VEAPETDFIIVALDLLSGLAESLP+HM PLV NSKL
Sbjct: 600 FTRCCNLIEKCVQQNQQHLMSPETVEAPETDFIIVALDLLSGLAESLPDHMPPLVTNSKL 659
Query: 1981 VELMLFCSLDVTPDVRQSCFALLGDLTKACPERVLPQSSNFIFFLAQNLDPSKISVCNNA 2160
+ELMLFCS+DVT DVRQSCFALLGDLTKACPERVL QSSNFIFFLAQNLDP+KISVCNNA
Sbjct: 660 IELMLFCSMDVTTDVRQSCFALLGDLTKACPERVLIQSSNFIFFLAQNLDPTKISVCNNA 719
Query: 2161 IWALGELALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLLENTAITIGRLGQCCGEELA 2340
IWALGEL+LKMGPAMKQF+GPI EPLI VIN+QQNMQRTLLENTAITIGRLGQ CGEELA
Sbjct: 720 IWALGELSLKMGPAMKQFVGPITEPLIAVINTQQNMQRTLLENTAITIGRLGQFCGEELA 779
Query: 2341 PHISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGVLNDFIFWCDAIASWTVPTD 2520
PHISRF+RPCCYSLRNIKDN EKESAFIGLCNMINMNPVGVLNDFIFWCDAIASWT PT+
Sbjct: 780 PHISRFIRPCCYSLRNIKDNTEKESAFIGLCNMINMNPVGVLNDFIFWCDAIASWTTPTE 839
Query: 2521 SLRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAF 2640
+LR LFAGILQSFK QVGD+NWN FI QLPPPLRERL+AF
Sbjct: 840 NLRALFAGILQSFKLQVGDYNWNAFIAQLPPPLRERLTAF 879
>gi|23510379|ref|NP_002261.2| transportin 1; karyopherin (importin)
beta 2; importin beta 2; M9 region interaction protein
[Homo sapiens]
gi|23510381|ref|NP_694858.1| transportin 1; karyopherin (importin)
beta 2; importin beta 2; M9 region interaction protein
[Homo sapiens]
gi|2842714|sp|Q92973|TNP1_HUMAN Transportin 1 (Importin beta-)2
(Karyopherin beta-2) (M9 region interaction protein)
(MIP)
gi|1656045|gb|AAB58254.1| karyopherin beta2 [Homo sapiens]
gi|25955635|gb|AAH40340.1| Transportin 1 [Homo sapiens]
Length = 890
Score = 859 bits (2220), Expect = 0.0
Identities = 437/891 (49%), Positives = 609/891 (68%), Gaps = 10/891 (1%)
Frame = +1
Query: 7 FQPDQHELEQVIQLLQHAHSTXXXXXXXXXXXXXXXXEHQKFCCYLVYILSDMKEMIDAT 186
++PD+ L+Q++QLL+ + S ++ F YL+++L+ +K D
Sbjct: 5 WKPDEQGLQQILQLLKESQSPDTTIQRTVQQKLEQLNQYPDFNNYLIFVLTKLKSE-DEP 63
Query: 187 SRSLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGDQEPLIRATVGIIVTTIVMEENM 366
+RSL+GL+LKNN++A + +P V F+++ CL +IGD PLIRATVGI++TTI + +
Sbjct: 64 TRSLSGLILKNNVKAHFQNFPNGVTDFIKSECLNNIGDSSPLIRATVGILITTIASKGEL 123
Query: 367 CDWPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYESEFL-RPI---MPKLLVFY 534
+WPDLL L ++L D EGA GALQK+ EDSA+ +S+ L RP+ +PK L F+
Sbjct: 124 QNWPDLLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVLDRPLNIMIPKFLQFF 183
Query: 535 EHHAAKMRALAMNCVNCILMVNNDPIDFAIDQFLTSLFARHNDNDEEVQKQLCRSLTLLL 714
+H + K+R+ A+ CVN ++ + ID F+ +LFA D + EV+K +CR+L +LL
Sbjct: 184 KHSSPKIRSHAVACVNQFIISRTQALMLHIDSFIENLFALAGDEEPEVRKNVCRALVMLL 243
Query: 715 DTHIEKMMPHLPNVIEYIIKKTQDHNESIALEACEFWLSIAENSDICRTMVLPHLDKLIP 894
+ +++++PH+ N++EY++++TQD +E++ALEACEFWL++AE IC+ +++ HL KLIP
Sbjct: 244 EVRMDRLLPHMHNIVEYMLQRTQDQDENVALEACEFWLTLAEQP-ICKDVLVRHLPKLIP 302
Query: 895 VLLGSMRYSETDPALKAND--EDSSVPDREEDIKPRFHKSK----QHGLGGLVESXXXXX 1056
VL+ M+YS+ D L D ED ++PD E+DI+PRFH+S+ QH G+ E
Sbjct: 303 VLVNGMKYSDIDIILLKGDVEEDETIPDSEQDIRPRFHRSRTVAQQHDEDGIEEEDDDDD 362
Query: 1057 XXXXXXXXXXWNIRRCSAASLDVLASIFGXXXXXXXXXXXXXXXMNDNWLVKESGILALG 1236
WN+R+CSAA+LDVLA+++ + W+VKESGIL LG
Sbjct: 363 EIDDDDTISDWNLRKCSAAALDVLANVYRDELLPHILPLLKELLFHHEWVVKESGILVLG 422
Query: 1237 AIAEGCMDGVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHIASDENFRQQFFKD 1416
AIAEGCM G++P+L ELIP ++ + DKK LVRSITCWTLSRY+ + S + K
Sbjct: 423 AIAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPP--DTYLKP 480
Query: 1417 VLANLLRCSLDGNKKVQEAACSAFATLEEEAGEQLIPFLGEILDQLVKAFQCYQAKNLLI 1596
++ LL+ LD NK+VQEAACSAFATLEEEA +L+P+L ILD LV AF YQ KNLLI
Sbjct: 481 LMTELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLAYILDTLVFAFSKYQHKNLLI 540
Query: 1597 LYDAIGTLANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISAIVSAMGQS 1776
LYDAIGTLA+SVG L+ P Y+QMLMPPL++KW L DEDK+LFPLLEC+S++ +A+
Sbjct: 541 LYDAIGTLADSVGHHLNKPEYIQMLMPPLIQKWNMLKDEDKDLFPLLECLSSVATALQSG 600
Query: 1777 FLPYIQPVFTRCCSLIEKCVQQNQQHIMAPDQVEAPETDFIIVALDLLSGLAESLPEHMD 1956
FLPY +PV+ RC +L++K + Q + PDQ EAP+ DF+IVALDLLSGLAE L +++
Sbjct: 601 FLPYCEPVYQRCVNLVQKTLAQAMLNNAQPDQYEAPDKDFMIVALDLLSGLAEGLGGNIE 660
Query: 1957 PLVANSKLVELMLFCSLDVTPDVRQSCFALLGDLTKACPERVLPQSSNFIFFLAQNLDPS 2136
LVA S ++ LM C D P+VRQS FALLGDLTKAC + V P ++F+ L NL+P
Sbjct: 661 QLVARSNILTLMYQCMQDKMPEVRQSSFALLGDLTKACFQHVKPCIADFMPILGTNLNPE 720
Query: 2137 KISVCNNAIWALGELALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLLENTAITIGRLG 2316
ISVCNNA WA+GE++++MG M+ +I ++ L+ +IN + N +TLLENTAITIGRLG
Sbjct: 721 FISVCNNATWAIGEISIQMGIEMQPYIPMVLHQLVEIIN-RPNTPKTLLENTAITIGRLG 779
Query: 2317 QCCGEELAPHISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGVLNDFIFWCDAI 2496
C +E+AP + +F+RP C SLRNI+DN EK+SAF G+C MI++NP GV+ DFIF+CDA+
Sbjct: 780 YVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICTMISVNPSGVIQDFIFFCDAV 839
Query: 2497 ASWTVPTDSLRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAFYQI 2649
ASW P D LR +F IL FK QVGD NW F Q P PL+ERL+AFY +
Sbjct: 840 ASWINPKDDLRDMFCKILHGFKNQVGDENWRRFSDQFPLPLKERLAAFYGV 890
>gi|1613834|gb|AAC50723.1| transportin [Homo sapiens]
Length = 890
Score = 858 bits (2217), Expect = 0.0
Identities = 437/891 (49%), Positives = 608/891 (68%), Gaps = 10/891 (1%)
Frame = +1
Query: 7 FQPDQHELEQVIQLLQHAHSTXXXXXXXXXXXXXXXXEHQKFCCYLVYILSDMKEMIDAT 186
++PD+ L+Q++QLL+ + S ++ F YL+++L+ +K D
Sbjct: 5 WKPDEQGLQQILQLLKESQSPDTTIQRTVQQKLEQLNQYPDFNNYLIFVLTKLKSE-DEP 63
Query: 187 SRSLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGDQEPLIRATVGIIVTTIVMEENM 366
+RSL+GL+LKNN++A + +P V F+++ CL +IGD PLIRATVGI++TTI + +
Sbjct: 64 TRSLSGLILKNNVKAHFQNFPNGVTDFIKSECLNNIGDSSPLIRATVGILITTIASKGEL 123
Query: 367 CDWPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYESEFL-RPI---MPKLLVFY 534
+WPDLL L ++L D EGA GALQK+ EDSA+ +S+ L RP+ +PK L F+
Sbjct: 124 QNWPDLLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVLDRPLNIMIPKFLQFF 183
Query: 535 EHHAAKMRALAMNCVNCILMVNNDPIDFAIDQFLTSLFARHNDNDEEVQKQLCRSLTLLL 714
+H + K+R+ A+ CVN ++ + ID F +LFA D + EV+K +CR+L +LL
Sbjct: 184 KHSSPKIRSHAVACVNQFIISRTQALMLHIDSFTENLFALAGDEEPEVRKNVCRALVMLL 243
Query: 715 DTHIEKMMPHLPNVIEYIIKKTQDHNESIALEACEFWLSIAENSDICRTMVLPHLDKLIP 894
+ +++++PH+ N++EY++++TQD +E++ALEACEFWL++AE IC+ +++ HL KLIP
Sbjct: 244 EVRMDRLLPHMHNIVEYMLQRTQDQDENVALEACEFWLTLAEQP-ICKDVLVRHLPKLIP 302
Query: 895 VLLGSMRYSETDPALKAND--EDSSVPDREEDIKPRFHKSK----QHGLGGLVESXXXXX 1056
VL+ M+YS+ D L D ED ++PD E+DI+PRFH+S+ QH G+ E
Sbjct: 303 VLVNGMKYSDIDIILLKGDVEEDETIPDSEQDIRPRFHRSRTVAQQHDEDGIEEEDDDDD 362
Query: 1057 XXXXXXXXXXWNIRRCSAASLDVLASIFGXXXXXXXXXXXXXXXMNDNWLVKESGILALG 1236
WN+R+CSAA+LDVLA+++ + W+VKESGIL LG
Sbjct: 363 EIDDDDTISDWNLRKCSAAALDVLANVYRDELLPHILPLLKELLFHHEWVVKESGILVLG 422
Query: 1237 AIAEGCMDGVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHIASDENFRQQFFKD 1416
AIAEGCM G++P+L ELIP ++ + DKK LVRSITCWTLSRY+ + S + K
Sbjct: 423 AIAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPP--DTYLKP 480
Query: 1417 VLANLLRCSLDGNKKVQEAACSAFATLEEEAGEQLIPFLGEILDQLVKAFQCYQAKNLLI 1596
++ LL+ LD NK+VQEAACSAFATLEEEA +L+P+L ILD LV AF YQ KNLLI
Sbjct: 481 LMTELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLAYILDTLVFAFSKYQHKNLLI 540
Query: 1597 LYDAIGTLANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISAIVSAMGQS 1776
LYDAIGTLA+SVG L+ P Y+QMLMPPL++KW L DEDK+LFPLLEC+S++ +A+
Sbjct: 541 LYDAIGTLADSVGHHLNKPEYIQMLMPPLIQKWNMLKDEDKDLFPLLECLSSVATALQSG 600
Query: 1777 FLPYIQPVFTRCCSLIEKCVQQNQQHIMAPDQVEAPETDFIIVALDLLSGLAESLPEHMD 1956
FLPY +PV+ RC +L++K + Q + PDQ EAP+ DF+IVALDLLSGLAE L +++
Sbjct: 601 FLPYCEPVYQRCVNLVQKTLAQAMLNNAQPDQYEAPDKDFMIVALDLLSGLAEGLGGNIE 660
Query: 1957 PLVANSKLVELMLFCSLDVTPDVRQSCFALLGDLTKACPERVLPQSSNFIFFLAQNLDPS 2136
LVA S ++ LM C D P+VRQS FALLGDLTKAC + V P ++F+ L NL+P
Sbjct: 661 QLVARSNILTLMYQCMQDKMPEVRQSSFALLGDLTKACFQHVKPCIADFMPILGTNLNPE 720
Query: 2137 KISVCNNAIWALGELALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLLENTAITIGRLG 2316
ISVCNNA WA+GE++++MG M+ +I ++ L+ +IN + N +TLLENTAITIGRLG
Sbjct: 721 FISVCNNATWAIGEISIQMGIEMQPYIPMVLHQLVEIIN-RPNTPKTLLENTAITIGRLG 779
Query: 2317 QCCGEELAPHISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGVLNDFIFWCDAI 2496
C +E+AP + +F+RP C SLRNI+DN EK+SAF G+C MI++NP GV+ DFIF+CDA+
Sbjct: 780 YVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICTMISVNPSGVIQDFIFFCDAV 839
Query: 2497 ASWTVPTDSLRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAFYQI 2649
ASW P D LR +F IL FK QVGD NW F Q P PL+ERL+AFY +
Sbjct: 840 ASWINPKDDLRDMFCKILHGFKNQVGDENWRRFSDQFPLPLKERLAAFYGV 890
>gi|30520133|ref|NP_848831.1| transportin 1; karyopherin (importin)
beta 2 [Mus musculus]
gi|45477303|sp|Q8BFY9|TNP1_MOUSE Transportin 1 (Importin beta-2)
(Karyopherin beta-2)
gi|26326571|dbj|BAC27029.1| unnamed protein product [Mus musculus]
gi|26337103|dbj|BAC32236.1| unnamed protein product [Mus musculus]
gi|33286914|gb|AAH55372.1| Tnpo1 protein [Mus musculus]
Length = 890
Score = 857 bits (2215), Expect = 0.0
Identities = 436/891 (48%), Positives = 609/891 (67%), Gaps = 10/891 (1%)
Frame = +1
Query: 7 FQPDQHELEQVIQLLQHAHSTXXXXXXXXXXXXXXXXEHQKFCCYLVYILSDMKEMIDAT 186
++PD+ L+Q++QLL+ + S ++ F YL+++L+ +K D
Sbjct: 5 WKPDEQGLQQILQLLKESQSPDTTIQRTVQQKLEQLNQYPDFNNYLIFVLTKLKSE-DEP 63
Query: 187 SRSLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGDQEPLIRATVGIIVTTIVMEENM 366
+RSL+GL+LKNN++A + +P V F+++ CL +IGD PLIRATVGI++TTI + +
Sbjct: 64 TRSLSGLILKNNVKAHFQNFPNGVTDFIKSECLNNIGDSSPLIRATVGILITTIASKGEL 123
Query: 367 CDWPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYESEFL-RPI---MPKLLVFY 534
+WPDLL L ++L D EGA GALQK+ EDSA+ +S+ L RP+ +PK L F+
Sbjct: 124 QNWPDLLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVLDRPLNIMIPKFLQFF 183
Query: 535 EHHAAKMRALAMNCVNCILMVNNDPIDFAIDQFLTSLFARHNDNDEEVQKQLCRSLTLLL 714
+H + K+R+ A+ CVN ++ + ID F+ +LFA D + EV+K +CR+L +LL
Sbjct: 184 KHSSPKIRSHAVACVNQFIISRTQALMLHIDSFIENLFALAGDEEAEVRKNVCRALVMLL 243
Query: 715 DTHIEKMMPHLPNVIEYIIKKTQDHNESIALEACEFWLSIAENSDICRTMVLPHLDKLIP 894
+ +++++PH+ N++EY++++TQD +E++ALEACEFWL++AE IC+ +++ HL KLIP
Sbjct: 244 EVRMDRLLPHMHNIVEYMLQRTQDQDENVALEACEFWLTLAEQP-ICKDVLVRHLPKLIP 302
Query: 895 VLLGSMRYSETDPALKAND--EDSSVPDREEDIKPRFHKSK----QHGLGGLVESXXXXX 1056
VL+ M+YS+ D L D ED ++PD E+DI+PRFH+S+ QH G+ E
Sbjct: 303 VLVNGMKYSDIDIILLKGDVEEDETIPDSEQDIRPRFHRSRTVAQQHEEDGIEEEDDDDD 362
Query: 1057 XXXXXXXXXXWNIRRCSAASLDVLASIFGXXXXXXXXXXXXXXXMNDNWLVKESGILALG 1236
WN+R+CSAA+LDVLA+++ + W+VKESGIL LG
Sbjct: 363 EIDDDDTISDWNLRKCSAAALDVLANVYRDELLPHILPLLKELLFHHEWVVKESGILVLG 422
Query: 1237 AIAEGCMDGVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHIASDENFRQQFFKD 1416
AIAEGCM G++P+L ELIP ++ + DKK LVRSITCWTLSRY+ + S + K
Sbjct: 423 AIAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPP--DTYLKP 480
Query: 1417 VLANLLRCSLDGNKKVQEAACSAFATLEEEAGEQLIPFLGEILDQLVKAFQCYQAKNLLI 1596
++ LL+ LD NK+VQEAACSAFATLEEEA +L+P+L ILD LV AF YQ KNLLI
Sbjct: 481 LMTELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLAYILDTLVFAFSKYQHKNLLI 540
Query: 1597 LYDAIGTLANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISAIVSAMGQS 1776
LYDAIGTLA+SVG L+ P Y+QMLMPPL++KW L DEDK+LFPLLEC+S++ +A+
Sbjct: 541 LYDAIGTLADSVGHHLNKPEYIQMLMPPLIQKWNMLKDEDKDLFPLLECLSSVATALQSG 600
Query: 1777 FLPYIQPVFTRCCSLIEKCVQQNQQHIMAPDQVEAPETDFIIVALDLLSGLAESLPEHMD 1956
FLPY +PV+ RC +L++K + Q + P+Q EAP+ DF+IVALDLLSGLAE L +++
Sbjct: 601 FLPYCEPVYQRCVNLVQKTLAQAMLNNAQPEQYEAPDKDFMIVALDLLSGLAEGLGGNIE 660
Query: 1957 PLVANSKLVELMLFCSLDVTPDVRQSCFALLGDLTKACPERVLPQSSNFIFFLAQNLDPS 2136
LVA S ++ LM C D P+VRQS FALLGDLTKAC + V P ++F+ L NL+P
Sbjct: 661 QLVARSNILTLMYQCMQDKMPEVRQSSFALLGDLTKACFQHVKPCIADFMPILGTNLNPE 720
Query: 2137 KISVCNNAIWALGELALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLLENTAITIGRLG 2316
ISVCNNA WA+GE++++MG M+ +I ++ L+ +IN + N +TLLENTAITIGRLG
Sbjct: 721 FISVCNNATWAIGEISIQMGIEMQPYIPMVLHQLVEIIN-RPNTPKTLLENTAITIGRLG 779
Query: 2317 QCCGEELAPHISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGVLNDFIFWCDAI 2496
C +E+AP + +F+RP C SLRNI+DN EK+SAF G+C MI++NP GV+ DFIF+CDA+
Sbjct: 780 YVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICTMISVNPSGVIQDFIFFCDAV 839
Query: 2497 ASWTVPTDSLRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAFYQI 2649
ASW P D LR +F IL FK QVGD NW F Q P PL+ERL+AFY +
Sbjct: 840 ASWINPKDDLRDMFCKILHGFKNQVGDENWRRFSDQFPLPLKERLAAFYGV 890
>gi|26325884|dbj|BAC26696.1| unnamed protein product [Mus musculus]
Length = 890
Score = 856 bits (2212), Expect = 0.0
Identities = 435/891 (48%), Positives = 609/891 (67%), Gaps = 10/891 (1%)
Frame = +1
Query: 7 FQPDQHELEQVIQLLQHAHSTXXXXXXXXXXXXXXXXEHQKFCCYLVYILSDMKEMIDAT 186
++PD+ L+Q++QLL+ + S ++ F YL+++L+ +K D
Sbjct: 5 WKPDEQGLQQILQLLKESQSPDTTIQRTVQQKLEQLNQYPDFNNYLIFVLTKLKSE-DEP 63
Query: 187 SRSLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGDQEPLIRATVGIIVTTIVMEENM 366
+RSL+GL+LKNN++A + +P V F+++ CL +IGD PLIRATVGI++TTI + +
Sbjct: 64 TRSLSGLILKNNVKAHFQNFPNGVTDFIKSECLNNIGDSSPLIRATVGILITTIASKGEL 123
Query: 367 CDWPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYESEFL-RPI---MPKLLVFY 534
+WPDLL L ++L D EGA GALQK+ EDSA+ +S+ L RP+ +PK L F+
Sbjct: 124 QNWPDLLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVLDRPLNIMIPKFLQFF 183
Query: 535 EHHAAKMRALAMNCVNCILMVNNDPIDFAIDQFLTSLFARHNDNDEEVQKQLCRSLTLLL 714
+H + K+R+ A+ CVN ++ + ID F+ +LFA D + EV+K +CR+L +LL
Sbjct: 184 KHSSPKIRSHAVACVNQFIISRTQALMLHIDSFIENLFALAGDEEAEVRKNVCRALVMLL 243
Query: 715 DTHIEKMMPHLPNVIEYIIKKTQDHNESIALEACEFWLSIAENSDICRTMVLPHLDKLIP 894
+ +++++PH+ N++EY++++TQD +E++ALEACEFWL++AE IC+ +++ HL KLIP
Sbjct: 244 EVRMDRLLPHMHNIVEYMLQRTQDQDENVALEACEFWLTLAEQP-ICKDVLVRHLPKLIP 302
Query: 895 VLLGSMRYSETDPALKAND--EDSSVPDREEDIKPRFHKSK----QHGLGGLVESXXXXX 1056
VL+ M+YS+ D L D ED ++PD E+DI+PRFH+S+ QH G+ E
Sbjct: 303 VLVNGMKYSDIDIILLKGDVEEDETIPDSEQDIRPRFHRSRTVAQQHEEDGIEEEDDDDD 362
Query: 1057 XXXXXXXXXXWNIRRCSAASLDVLASIFGXXXXXXXXXXXXXXXMNDNWLVKESGILALG 1236
WN+R+CSA++LDVLA+++ + W+VKESGIL LG
Sbjct: 363 EIDDDDTISDWNLRKCSASALDVLANVYRDELLPHILPLLKELLFHHEWVVKESGILVLG 422
Query: 1237 AIAEGCMDGVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHIASDENFRQQFFKD 1416
AIAEGCM G++P+L ELIP ++ + DKK LVRSITCWTLSRY+ + S + K
Sbjct: 423 AIAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPP--DTYLKP 480
Query: 1417 VLANLLRCSLDGNKKVQEAACSAFATLEEEAGEQLIPFLGEILDQLVKAFQCYQAKNLLI 1596
++ LL+ LD NK+VQEAACSAFATLEEEA +L+P+L ILD LV AF YQ KNLLI
Sbjct: 481 LMTELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLAYILDTLVFAFSKYQHKNLLI 540
Query: 1597 LYDAIGTLANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISAIVSAMGQS 1776
LYDAIGTLA+SVG L+ P Y+QMLMPPL++KW L DEDK+LFPLLEC+S++ +A+
Sbjct: 541 LYDAIGTLADSVGHHLNKPEYIQMLMPPLIQKWNMLKDEDKDLFPLLECLSSVATALQSG 600
Query: 1777 FLPYIQPVFTRCCSLIEKCVQQNQQHIMAPDQVEAPETDFIIVALDLLSGLAESLPEHMD 1956
FLPY +PV+ RC +L++K + Q + P+Q EAP+ DF+IVALDLLSGLAE L +++
Sbjct: 601 FLPYCEPVYQRCVNLVQKTLAQAMLNNAQPEQYEAPDKDFMIVALDLLSGLAEGLGGNIE 660
Query: 1957 PLVANSKLVELMLFCSLDVTPDVRQSCFALLGDLTKACPERVLPQSSNFIFFLAQNLDPS 2136
LVA S ++ LM C D P+VRQS FALLGDLTKAC + V P ++F+ L NL+P
Sbjct: 661 QLVARSNILTLMYQCMQDKMPEVRQSSFALLGDLTKACFQHVKPCIADFMPILGTNLNPE 720
Query: 2137 KISVCNNAIWALGELALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLLENTAITIGRLG 2316
ISVCNNA WA+GE++++MG M+ +I ++ L+ +IN + N +TLLENTAITIGRLG
Sbjct: 721 FISVCNNATWAIGEISIQMGIEMQPYIPMVLHQLVEIIN-RPNTPKTLLENTAITIGRLG 779
Query: 2317 QCCGEELAPHISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGVLNDFIFWCDAI 2496
C +E+AP + +F+RP C SLRNI+DN EK+SAF G+C MI++NP GV+ DFIF+CDA+
Sbjct: 780 YVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICTMISVNPSGVIQDFIFFCDAV 839
Query: 2497 ASWTVPTDSLRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAFYQI 2649
ASW P D LR +F IL FK QVGD NW F Q P PL+ERL+AFY +
Sbjct: 840 ASWINPKDDLRDMFCKILHGFKNQVGDENWRRFSDQFPLPLKERLAAFYGV 890
>gi|1622943|gb|AAB68948.1| MIP [Homo sapiens]
Length = 890
Score = 856 bits (2212), Expect = 0.0
Identities = 436/891 (48%), Positives = 608/891 (67%), Gaps = 10/891 (1%)
Frame = +1
Query: 7 FQPDQHELEQVIQLLQHAHSTXXXXXXXXXXXXXXXXEHQKFCCYLVYILSDMKEMIDAT 186
++PD+ L+Q++QLL+ + S ++ F YL+++L+ +K D
Sbjct: 5 WKPDEQGLQQILQLLKESQSPDTTIQRTVQQKLEQLNQYPDFNNYLIFVLTKLKSE-DEP 63
Query: 187 SRSLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGDQEPLIRATVGIIVTTIVMEENM 366
+RSL+GL+LKNN++A + +P V F+++ C +IGD PLIRATVGI++TTI + +
Sbjct: 64 TRSLSGLILKNNVKAHFQNFPNGVTDFIKSECSNNIGDSSPLIRATVGILITTIASKGEL 123
Query: 367 CDWPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYESEFL-RPI---MPKLLVFY 534
+WPDLL L ++L D EGA GALQK+ EDSA+ +S+ L RP+ +PK L F+
Sbjct: 124 QNWPDLLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVLDRPLNIMIPKFLQFF 183
Query: 535 EHHAAKMRALAMNCVNCILMVNNDPIDFAIDQFLTSLFARHNDNDEEVQKQLCRSLTLLL 714
+H + K+R+ A+ CVN ++ + ID F+ +LFA D + EV+K +CR+L +LL
Sbjct: 184 KHSSPKIRSHAVACVNQFIISRTQALMLHIDSFIENLFALAGDEEPEVRKNVCRALVMLL 243
Query: 715 DTHIEKMMPHLPNVIEYIIKKTQDHNESIALEACEFWLSIAENSDICRTMVLPHLDKLIP 894
+ +++++PH+ N++EY++++TQD +E++ALEACEFWL++AE IC+ +++ HL KLIP
Sbjct: 244 EVRMDRLLPHMHNIVEYMLQRTQDQDENVALEACEFWLTLAEQP-ICKDVLVRHLPKLIP 302
Query: 895 VLLGSMRYSETDPALKAND--EDSSVPDREEDIKPRFHKSK----QHGLGGLVESXXXXX 1056
VL+ M+YS+ D L D ED ++PD E+DI+PRFH+S+ QH G+ E
Sbjct: 303 VLVNGMKYSDIDIILLKGDVEEDETIPDSEQDIRPRFHRSRTVAQQHDEDGIEEEDDDDD 362
Query: 1057 XXXXXXXXXXWNIRRCSAASLDVLASIFGXXXXXXXXXXXXXXXMNDNWLVKESGILALG 1236
WN+R+CSAA+LDVLA+++ + W+VKESGIL LG
Sbjct: 363 EIDDDDTISDWNLRKCSAAALDVLANVYRDELLPHILPLLKELLFHHEWVVKESGILVLG 422
Query: 1237 AIAEGCMDGVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHIASDENFRQQFFKD 1416
AIAEGCM G++P+L ELIP ++ + DKK LVRSITCWTLSRY+ + S + K
Sbjct: 423 AIAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPP--DTYLKP 480
Query: 1417 VLANLLRCSLDGNKKVQEAACSAFATLEEEAGEQLIPFLGEILDQLVKAFQCYQAKNLLI 1596
++ LL+ LD NK+VQEAACSAFATLEEEA +L+P+L ILD LV AF YQ KNLLI
Sbjct: 481 LMTELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLAYILDTLVFAFSKYQHKNLLI 540
Query: 1597 LYDAIGTLANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISAIVSAMGQS 1776
LYDAIGTLA+SVG L+ P Y+QMLMPPL++KW L DEDK+LFPLLEC+S++ +A+
Sbjct: 541 LYDAIGTLADSVGHHLNKPEYIQMLMPPLIQKWNMLKDEDKDLFPLLECLSSVATALQSG 600
Query: 1777 FLPYIQPVFTRCCSLIEKCVQQNQQHIMAPDQVEAPETDFIIVALDLLSGLAESLPEHMD 1956
FLPY +PV+ RC +L++K + Q + PDQ EAP+ DF+IVALDLLSGLAE L +++
Sbjct: 601 FLPYCEPVYQRCVNLVQKTLAQAMLNNAQPDQYEAPDKDFMIVALDLLSGLAEGLGGNIE 660
Query: 1957 PLVANSKLVELMLFCSLDVTPDVRQSCFALLGDLTKACPERVLPQSSNFIFFLAQNLDPS 2136
LVA S ++ LM C D P+VRQS FALLGDLTKAC + V P ++F+ L NL+P
Sbjct: 661 LLVARSNILTLMYQCMQDKMPEVRQSSFALLGDLTKACFQHVKPCIADFMPILGTNLNPE 720
Query: 2137 KISVCNNAIWALGELALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLLENTAITIGRLG 2316
ISVCNNA WA+GE++++MG M+ +I ++ L+ +IN + N +TLLENTAITIGRLG
Sbjct: 721 FISVCNNATWAIGEISIQMGIEMQPYIPMVLHQLVEIIN-RPNTPKTLLENTAITIGRLG 779
Query: 2317 QCCGEELAPHISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGVLNDFIFWCDAI 2496
C +E+AP + +F+RP C SLRNI+DN EK+SAF G+C MI++NP GV+ DFIF+CDA+
Sbjct: 780 YVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICTMISVNPSGVIQDFIFFCDAV 839
Query: 2497 ASWTVPTDSLRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAFYQI 2649
ASW P D LR +F IL FK QVGD NW F Q P PL+ERL+AFY +
Sbjct: 840 ASWINPKDDLRDMFCKILHGFKNQVGDENWRRFSDQFPLPLKERLAAFYGV 890
>gi|3293344|gb|AAC25709.1| transportin; TRN [Xenopus laevis]
Length = 885
Score = 841 bits (2172), Expect = 0.0
Identities = 433/890 (48%), Positives = 600/890 (66%), Gaps = 11/890 (1%)
Frame = +1
Query: 13 PDQHELEQVIQLLQHAHSTXXXXXXXXXXXXXXXXEHQKFCCYLVYILSDMKEMIDATSR 192
PD+ L+Q++QLL+ + S + F YL+++L+ +K D +R
Sbjct: 1 PDEQGLQQILQLLKESQSPDNNTQRAVQQKLEQLNQFPDFNNYLIFVLTKLKSE-DEPTR 59
Query: 193 SLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGDQEPLIRATVGIIVTTIVMEENMCD 372
SL+GL+LKNN++A + +P V F+++ CL +IGD PLIRATVGI++TTI + + +
Sbjct: 60 SLSGLILKNNVKAHFQNFPNGVTDFIKSECLNNIGDSSPLIRATVGILITTIASKGELQN 119
Query: 373 WPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYESEFL-RPI---MPKLLVFYEH 540
WP+LL L +L D EGA GALQK+ EDSA+ +S+ L RP+ +PK L F++H
Sbjct: 120 WPELLPKLCGLLDSEDYNTCEGAFGALQKICEDSAEILDSDVLERPLNVMIPKFLQFFKH 179
Query: 541 HAAKMRALAMNCVNCILMVNNDPIDFAIDQFLTSLFARHNDNDEEVQKQLCRSLTLLLDT 720
+ K+R+ A+ CVN ++ + ID F+ +LFA D + EV+K +CR+L +LL+
Sbjct: 180 SSPKIRSHAVACVNQFIIGRTQALMLHIDSFIENLFALATDEEPEVRKNVCRALVMLLEV 239
Query: 721 HIEKMMPHLPNVIEYIIKKTQDHNESIALEACEFWLSIAENSDICRTMVLPHLDKLIPVL 900
+++++PH+ N++EY++ +TQD +E++ALEACEFWL++AE IC+ ++ HL KLIPVL
Sbjct: 240 RMDRLLPHMHNIVEYMLLRTQDQDENVALEACEFWLTLAEQP-ICKEVLCRHLAKLIPVL 298
Query: 901 LGSMRYSETDPALKAND--EDSSVPDREEDIKPRFHKSKQ----HGLGGLVESXXXXXXX 1062
+ M+YSE D L D ED +VPD E+DI+PRFH+S+ H G+ +
Sbjct: 299 VNGMKYSEIDIILLKGDVEEDEAVPDSEQDIRPRFHRSRTVAQPHEEDGIEDDDDDDDNE 358
Query: 1063 XXXXXXXX-WNIRRCSAASLDVLASIFGXXXXXXXXXXXXXXXMNDNWLVKESGILALGA 1239
WN+R+CSAA+LDVLA++F + W++KESGIL LGA
Sbjct: 359 LDDDENISDWNLRKCSAAALDVLANVFREELLPHILPLLKELLFHPEWVIKESGILVLGA 418
Query: 1240 IAEGCMDGVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHIASDENFRQQFFKDV 1419
IAEGCM G++P+L ELIP + + DKK LVRSITCWTLSRY+ + S K +
Sbjct: 419 IAEGCMQGMIPYLPELIPHLTQCLSDKKALVRSITCWTLSRYAHWVVSQPP--DMCLKPL 476
Query: 1420 LANLLRCSLDGNKKVQEAACSAFATLEEEAGEQLIPFLGEILDQLVKAFQCYQAKNLLIL 1599
+ LL+ LD NK+VQEAACSAFATLEEEA +L+P+L ILD LV AF YQ KNLLIL
Sbjct: 477 MTELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLAYILDTLVFAFSKYQHKNLLIL 536
Query: 1600 YDAIGTLANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISAIVSAMGQSF 1779
YDAIGTLA+SVG L+ P Y+QMLMPPL++KW L DEDK+LFPLLEC+S++ +A+ F
Sbjct: 537 YDAIGTLADSVGHHLNKPEYIQMLMPPLIQKWNVLKDEDKDLFPLLECLSSVATALQSGF 596
Query: 1780 LPYIQPVFTRCCSLIEKCVQQNQQHIMAPDQVEAPETDFIIVALDLLSGLAESLPEHMDP 1959
PY +PV+ RC +L++K +QQ+ H PDQ E+P+ DF+IVALDLLSGLAE L H++
Sbjct: 597 FPYCEPVYQRCVNLVQKTLQQSMLHNSQPDQYESPDKDFMIVALDLLSGLAEGLGGHIEQ 656
Query: 1960 LVANSKLVELMLFCSLDVTPDVRQSCFALLGDLTKACPERVLPQSSNFIFFLAQNLDPSK 2139
LVA S ++ LM C D P+VRQS FALLGDLTKAC + V ++F+ L NL+P
Sbjct: 657 LVARSNILTLMYQCMQDKMPEVRQSSFALLGDLTKACFQHVKSCIADFMPILGTNLNPEL 716
Query: 2140 ISVCNNAIWALGELALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLLENTAITIGRLGQ 2319
ISVCNNA WA+GE++++MG M+ ++ ++ L+ +IN + N +TLLENTAITIGRLG
Sbjct: 717 ISVCNNATWAIGEISIQMGIDMQPYVPMVLHQLVEIIN-RPNTPKTLLENTAITIGRLGY 775
Query: 2320 CCGEELAPHISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGVLNDFIFWCDAIA 2499
C +E+AP + +F+RP C SLRNI+DN EK+SAF G+C MI++NP GV+ DFIF+CDA+A
Sbjct: 776 VCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICTMISVNPGGVVQDFIFFCDAVA 835
Query: 2500 SWTVPTDSLRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAFYQI 2649
SW P + LR +F IL FK QVGD NW F Q P PL+ERL+A+Y +
Sbjct: 836 SWINPKEDLRDMFCKILHGFKNQVGDENWRRFSDQFPLPLKERLAAYYGV 885
>gi|21703780|ref|NP_663365.1| karyopherin (importin) beta 2b [Mus
musculus]
gi|45504421|sp|Q99LG2|TNP2_MOUSE Transportin 2 (Karyopherin beta-2b)
gi|13096961|gb|AAH03275.1| Karyopherin (importin) beta 2b [Mus
musculus]
Length = 887
Score = 840 bits (2171), Expect = 0.0
Identities = 438/892 (49%), Positives = 597/892 (66%), Gaps = 9/892 (1%)
Frame = +1
Query: 1 MAFQPDQHELEQVIQLLQHAHSTXXXXXXXXXXXXXXXXEHQKFCCYLVYILSDMKEMID 180
M +QPD+ L+QV+QLL+ + S + F YL+++L+ +K D
Sbjct: 1 MDWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSE-D 59
Query: 181 ATSRSLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGDQEPLIRATVGIIVTTIVMEE 360
+RSL+GL+LKNN++A + +P V F++ CL +IGD LIRAT+GI++TTI +
Sbjct: 60 EPTRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKG 119
Query: 361 NMCDWPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYESEFL-RPI---MPKLLV 528
+ WP+LL L +L D EGA GALQK+ EDS++ +S+ L RP+ +PK L
Sbjct: 120 ELQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQ 179
Query: 529 FYEHHAAKMRALAMNCVNCILMVNNDPIDFAIDQFLTSLFARHNDNDEEVQKQLCRSLTL 708
F++H + K+R+ A+ CVN +M + ID F+ LFA D+D EV+K +CR+L +
Sbjct: 180 FFKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVM 239
Query: 709 LLDTHIEKMMPHLPNVIEYIIKKTQDHNESIALEACEFWLSIAENSDICRTMVLPHLDKL 888
LL+ I++++PH+ ++I+Y++++TQDH+E++ALEACEFWL++AE IC+ ++ HL +L
Sbjct: 240 LLEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQP-ICKEVLASHLVQL 298
Query: 889 IPVLLGSMRYSETDPALKAND--EDSSVPDREEDIKPRFHKSKQHGLGGLVE---SXXXX 1053
IP+L+ M+YSE D L D ED +VPD E+DIKPRFHKS+ L E S
Sbjct: 299 IPILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLTHEAERPDSSEDA 358
Query: 1054 XXXXXXXXXXXWNIRRCSAASLDVLASIFGXXXXXXXXXXXXXXXMNDNWLVKESGILAL 1233
WN+R+CSAA+LDVLA++F + W+VKESGIL L
Sbjct: 359 EDDDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVL 418
Query: 1234 GAIAEGCMDGVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHIASDENFRQQFFK 1413
GAIAEGCM G+VP+L ELIP ++ + DKK LVRSI CWTLSRY+ + S K
Sbjct: 419 GAIAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPP--DMHLK 476
Query: 1414 DVLANLLRCSLDGNKKVQEAACSAFATLEEEAGEQLIPFLGEILDQLVKAFQCYQAKNLL 1593
++ LL+ LDGNK+VQEAACSAFATLEEEA +L+P+L ILD LV AF YQ KNLL
Sbjct: 477 PLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLL 536
Query: 1594 ILYDAIGTLANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISAIVSAMGQ 1773
ILYDAIGTLA+SVG L+ P Y+Q LMPPL++KW L DEDK+LFPLLEC+S++ +A+
Sbjct: 537 ILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQS 596
Query: 1774 SFLPYIQPVFTRCCSLIEKCVQQNQQHIMAPDQVEAPETDFIIVALDLLSGLAESLPEHM 1953
FLPY +PV+ RC +L++K + Q + P+Q EAP+ DF+IVALDLLSGLAE L H+
Sbjct: 597 GFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHV 656
Query: 1954 DPLVANSKLVELMLFCSLDVTPDVRQSCFALLGDLTKACPERVLPQSSNFIFFLAQNLDP 2133
+ LVA S ++ L+ C D P+VRQS FALLGDLTKAC V P + F+ L NL+P
Sbjct: 657 EQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNP 716
Query: 2134 SKISVCNNAIWALGELALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLLENTAITIGRL 2313
ISVCNNA WA+GE+ ++MG M+ ++ ++ L+ +IN + N +TLLENTAITIGRL
Sbjct: 717 EFISVCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIIN-RPNTPKTLLENTAITIGRL 775
Query: 2314 GQCCGEELAPHISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGVLNDFIFWCDA 2493
G C +E+AP + +F+RP C SLRNI+DN EK+SAF G+C MI +NP GV+ DFIF+CDA
Sbjct: 776 GYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDA 835
Query: 2494 IASWTVPTDSLRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAFYQI 2649
+ASW P D LR +F IL FK QVG+ NW F Q PP L+ERL+AFY +
Sbjct: 836 VASWVSPKDDLRDMFYKILHGFKDQVGEENWQQFSEQFPPLLKERLAAFYGV 887
>gi|48675813|ref|NP_038461.2| transportin 2 (importin 3, karyopherin
beta 2b); karyopherin beta 2b, transportin; importin 3
[Homo sapiens]
gi|47938907|gb|AAH72420.1| Transportin 2 (importin 3, karyopherin
beta 2b) [Homo sapiens]
Length = 887
Score = 839 bits (2167), Expect = 0.0
Identities = 437/892 (48%), Positives = 596/892 (65%), Gaps = 9/892 (1%)
Frame = +1
Query: 1 MAFQPDQHELEQVIQLLQHAHSTXXXXXXXXXXXXXXXXEHQKFCCYLVYILSDMKEMID 180
M +QPD+ L+QV+QLL+ + S + F YL+++L+ +K D
Sbjct: 1 MDWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSE-D 59
Query: 181 ATSRSLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGDQEPLIRATVGIIVTTIVMEE 360
+RSL+GL+LKNN++A + +P V F++ CL +IGD LIRAT+GI++TTI +
Sbjct: 60 EPTRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKG 119
Query: 361 NMCDWPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYESEFL-RPI---MPKLLV 528
+ WP+LL L +L D EGA GALQK+ EDS++ +S+ L RP+ +PK L
Sbjct: 120 ELQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQ 179
Query: 529 FYEHHAAKMRALAMNCVNCILMVNNDPIDFAIDQFLTSLFARHNDNDEEVQKQLCRSLTL 708
F++H + K+R+ A+ CVN +M + ID F+ LFA D+D EV+K +CR+L +
Sbjct: 180 FFKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVM 239
Query: 709 LLDTHIEKMMPHLPNVIEYIIKKTQDHNESIALEACEFWLSIAENSDICRTMVLPHLDKL 888
LL+ I++++PH+ ++I+Y++++TQDH+E++ALEACEFWL++AE IC+ ++ HL +L
Sbjct: 240 LLEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQP-ICKEVLASHLVQL 298
Query: 889 IPVLLGSMRYSETDPALKAND--EDSSVPDREEDIKPRFHKSKQHGLGGLVE---SXXXX 1053
IP+L+ M+YSE D L D ED +VPD E+DIKPRFHKS+ L E
Sbjct: 299 IPILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDA 358
Query: 1054 XXXXXXXXXXXWNIRRCSAASLDVLASIFGXXXXXXXXXXXXXXXMNDNWLVKESGILAL 1233
WN+R+CSAA+LDVLA++F + W+VKESGIL L
Sbjct: 359 EDDDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVL 418
Query: 1234 GAIAEGCMDGVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHIASDENFRQQFFK 1413
GAIAEGCM G+VP+L ELIP ++ + DKK LVRSI CWTLSRY+ + S K
Sbjct: 419 GAIAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPP--DMHLK 476
Query: 1414 DVLANLLRCSLDGNKKVQEAACSAFATLEEEAGEQLIPFLGEILDQLVKAFQCYQAKNLL 1593
++ LL+ LDGNK+VQEAACSAFATLEEEA +L+P+L ILD LV AF YQ KNLL
Sbjct: 477 PLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLL 536
Query: 1594 ILYDAIGTLANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISAIVSAMGQ 1773
ILYDAIGTLA+SVG L+ P Y+Q LMPPL++KW L DEDK+LFPLLEC+S++ +A+
Sbjct: 537 ILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQS 596
Query: 1774 SFLPYIQPVFTRCCSLIEKCVQQNQQHIMAPDQVEAPETDFIIVALDLLSGLAESLPEHM 1953
FLPY +PV+ RC +L++K + Q + P+Q EAP+ DF+IVALDLLSGLAE L H+
Sbjct: 597 GFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHV 656
Query: 1954 DPLVANSKLVELMLFCSLDVTPDVRQSCFALLGDLTKACPERVLPQSSNFIFFLAQNLDP 2133
+ LVA S ++ L+ C D P+VRQS FALLGDLTKAC V P + F+ L NL+P
Sbjct: 657 EQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNP 716
Query: 2134 SKISVCNNAIWALGELALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLLENTAITIGRL 2313
ISVCNNA WA+GE+ ++MG M+ ++ ++ L+ +IN + N +TLLENTAITIGRL
Sbjct: 717 EFISVCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIIN-RPNTPKTLLENTAITIGRL 775
Query: 2314 GQCCGEELAPHISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGVLNDFIFWCDA 2493
G C +E+AP + +F+RP C SLRNI+DN EK+SAF G+C MI +NP GV+ DFIF+CDA
Sbjct: 776 GYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDA 835
Query: 2494 IASWTVPTDSLRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAFYQI 2649
+ASW P D LR +F IL FK QVG+ NW F Q PP L+ERL+AFY +
Sbjct: 836 VASWVSPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFYGV 887
>gi|34851417|ref|XP_222478.2| similar to karyopherin (importin) beta
2b [Rattus norvegicus]
Length = 887
Score = 839 bits (2167), Expect = 0.0
Identities = 437/892 (48%), Positives = 596/892 (65%), Gaps = 9/892 (1%)
Frame = +1
Query: 1 MAFQPDQHELEQVIQLLQHAHSTXXXXXXXXXXXXXXXXEHQKFCCYLVYILSDMKEMID 180
M +QPD+ L+QV+QLL+ + S + F YL+++L+ +K D
Sbjct: 1 MDWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSE-D 59
Query: 181 ATSRSLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGDQEPLIRATVGIIVTTIVMEE 360
+RSL+GL+LKNN++A + +P V F++ CL +IGD LIRAT+GI++TTI +
Sbjct: 60 EPTRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKG 119
Query: 361 NMCDWPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYESEFL-RPI---MPKLLV 528
+ WP+LL L +L D EGA GALQK+ EDS++ +S+ L RP+ +PK L
Sbjct: 120 ELQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQ 179
Query: 529 FYEHHAAKMRALAMNCVNCILMVNNDPIDFAIDQFLTSLFARHNDNDEEVQKQLCRSLTL 708
F++H + K+R+ A+ CVN +M + ID F+ LFA D+D EV+K +CR+L +
Sbjct: 180 FFKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVM 239
Query: 709 LLDTHIEKMMPHLPNVIEYIIKKTQDHNESIALEACEFWLSIAENSDICRTMVLPHLDKL 888
LL+ I++++PH+ ++I+Y++++TQDH+E++ALEACEFWL++AE IC+ ++ HL +L
Sbjct: 240 LLEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQP-ICKEVLASHLVQL 298
Query: 889 IPVLLGSMRYSETDPALKAND--EDSSVPDREEDIKPRFHKSKQHGLGGLVE---SXXXX 1053
IP+L+ M+YSE D L D ED +VPD E+DIKPRFHKS+ L E
Sbjct: 299 IPILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLTHEAERPDGSEDA 358
Query: 1054 XXXXXXXXXXXWNIRRCSAASLDVLASIFGXXXXXXXXXXXXXXXMNDNWLVKESGILAL 1233
WN+R+CSAA+LDVLA++F + W+VKESGIL L
Sbjct: 359 EDDDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVL 418
Query: 1234 GAIAEGCMDGVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHIASDENFRQQFFK 1413
GAIAEGCM G+VP+L ELIP ++ + DKK LVRSI CWTLSRY+ + S K
Sbjct: 419 GAIAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPP--DMHLK 476
Query: 1414 DVLANLLRCSLDGNKKVQEAACSAFATLEEEAGEQLIPFLGEILDQLVKAFQCYQAKNLL 1593
++ LL+ LDGNK+VQEAACSAFATLEEEA +L+P+L ILD LV AF YQ KNLL
Sbjct: 477 PLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLL 536
Query: 1594 ILYDAIGTLANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISAIVSAMGQ 1773
ILYDAIGTLA+SVG L+ P Y+Q LMPPL++KW L DEDK+LFPLLEC+S++ +A+
Sbjct: 537 ILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQS 596
Query: 1774 SFLPYIQPVFTRCCSLIEKCVQQNQQHIMAPDQVEAPETDFIIVALDLLSGLAESLPEHM 1953
FLPY +PV+ RC +L++K + Q + P+Q EAP+ DF+IVALDLLSGLAE L H+
Sbjct: 597 GFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHV 656
Query: 1954 DPLVANSKLVELMLFCSLDVTPDVRQSCFALLGDLTKACPERVLPQSSNFIFFLAQNLDP 2133
+ LVA S ++ L+ C D P+VRQS FALLGDLTKAC V P + F+ L NL+P
Sbjct: 657 EQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNP 716
Query: 2134 SKISVCNNAIWALGELALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLLENTAITIGRL 2313
ISVCNNA WA+GE+ ++MG M+ ++ ++ L+ +IN + N +TLLENTAITIGRL
Sbjct: 717 EFISVCNNATWAIGEICMQMGAEMQPYVQMVLSNLVEIIN-RPNTPKTLLENTAITIGRL 775
Query: 2314 GQCCGEELAPHISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGVLNDFIFWCDA 2493
G C +E+AP + +F+RP C SLRNI+DN EK+SAF G+C MI +NP GV+ DFIF+CDA
Sbjct: 776 GYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDA 835
Query: 2494 IASWTVPTDSLRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAFYQI 2649
+ASW P D LR +F IL FK QVG+ NW F Q PP L+ERL+AFY +
Sbjct: 836 VASWVSPKDDLRDMFYKILHGFKDQVGEENWQQFSEQFPPLLKERLAAFYGV 887
>gi|48095991|ref|XP_392373.1| similar to transportin 1; karyopherin
(importin) beta 2 [Apis mellifera]
Length = 933
Score = 837 bits (2163), Expect = 0.0
Identities = 436/902 (48%), Positives = 597/902 (65%), Gaps = 19/902 (2%)
Frame = +1
Query: 1 MAFQPDQHELEQVIQLLQHAHSTXXXXXXXXXXXXXXXXEHQKFCCYLVYILSDMKEMID 180
MA+QP + L Q++ LL+ + S + F YL+++L+ + D
Sbjct: 37 MAWQPQEEGLRQILTLLKESQSPDTATQRAVQEKLEELNKFPDFNNYLIFVLTKLTSE-D 95
Query: 181 ATSRSLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGDQEPLIRATVGIIVTTIVMEE 360
+RSL+GL+LKNN++A + K+ +V F++ CL ++GD PLIRATVGI++TTI +
Sbjct: 96 EPTRSLSGLILKNNVKAHFYKFLPEVTNFIKQECLSAVGDPSPLIRATVGILITTIASKG 155
Query: 361 NMCDWPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYESEFL-RPI---MPKLLV 528
+ WP+LL L +L D + EGA GALQK+ EDS++ +S+ L RP+ +PK L
Sbjct: 156 ELTRWPELLPALCQMLDSQDYNVCEGAFGALQKICEDSSEILDSDALNRPLNVLIPKFLQ 215
Query: 529 FYEHHAAKMRALAMNCVNCILMVNNDPIDFAIDQFLTSLFARHNDNDEEVQKQLCRSLTL 708
F+ H + K+R+ A+ CVN ++ + ID FL +LF ND+D +V+K +CR+L +
Sbjct: 216 FFRHSSPKIRSHAIACVNQFIVNRTQALMIHIDSFLENLFHLANDDDSDVRKHVCRALVM 275
Query: 709 LLDTHIEKMMPHLPNVIEYIIKKTQDHNESIALEACEFWLSIAENSDICRTMVLPHLDKL 888
LL+ +++++PH+ N+IEY++ +TQD +E +ALEACEFWLS+AE IC+ + PHL +L
Sbjct: 276 LLEVRMDRLIPHMHNIIEYMLMRTQDLDEGVALEACEFWLSLAEQP-ICKEALAPHLPRL 334
Query: 889 IPVLLGSMRYSETDPALKAND--EDSSVPDREEDIKPRFHKSKQHGL------------G 1026
+P+L+ M+YSE D L D ED +PDREEDI+PRF KSK H G
Sbjct: 335 VPILVRGMKYSEIDIILLKGDVEEDEMIPDREEDIRPRFPKSKTHHTHHANMNKHTNENG 394
Query: 1027 GLVESXXXXXXX-XXXXXXXXWNIRRCSAASLDVLASIFGXXXXXXXXXXXXXXXMNDNW 1203
G E WN+R+CSAA+LD+LA++F + +W
Sbjct: 395 GCDEDDTDAEDGCDDDSTLSDWNLRKCSAAALDMLANVFREELLPVLVPILKETLFHQDW 454
Query: 1204 LVKESGILALGAIAEGCMDGVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHIAS 1383
+KESGILALGAIAEGCM G++PHL ELIP++++ + DKK LVR+ITCWTLSRY+ + +
Sbjct: 455 EIKESGILALGAIAEGCMSGMIPHLSELIPYLISCLSDKKALVRAITCWTLSRYAHWVCA 514
Query: 1384 DENFRQQFFKDVLANLLRCSLDGNKKVQEAACSAFATLEEEAGEQLIPFLGEILDQLVKA 1563
+ K ++ LL+ LDGNK+VQEAACSAFATLEEEA +L+P+LG IL+ LV A
Sbjct: 515 QPH--DTHLKPLMTELLKRVLDGNKRVQEAACSAFATLEEEACTELVPYLGFILETLVFA 572
Query: 1564 FQCYQAKNLLILYDAIGTLANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLEC 1743
F YQ KNLLILYDAIGTLA+SVG L+ P Y+ +LMPPL+ KW L DEDK+LFPLLEC
Sbjct: 573 FGKYQHKNLLILYDAIGTLADSVGHHLNKPDYINLLMPPLINKWNVLKDEDKDLFPLLEC 632
Query: 1744 ISAIVSAMGQSFLPYIQPVFTRCCSLIEKCVQQNQQHIMAPDQVEAPETDFIIVALDLLS 1923
+S++ +A+ FLPY +PV+ RC SL+E+ + Q+ + +P+Q EAP+ DF+IVALDLLS
Sbjct: 633 LSSVATALRSGFLPYCEPVYRRCVSLVEQTLNQHIANTQSPEQFEAPDKDFMIVALDLLS 692
Query: 1924 GLAESLPEHMDPLVANSKLVELMLFCSLDVTPDVRQSCFALLGDLTKACPERVLPQSSNF 2103
GLAE L HM+ LV NS +++L+ C DV P+VRQS FALLGDLTKAC + VLP F
Sbjct: 693 GLAEGLDGHMERLVMNSNVMQLLYQCMQDVMPEVRQSSFALLGDLTKACFQHVLPCIPEF 752
Query: 2104 IFFLAQNLDPSKISVCNNAIWALGELALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLL 2283
+ L QNL+P ISVCNNA WA+GE+A+K+G +I I+ LI +IN + N +TLL
Sbjct: 753 MPILGQNLNPEFISVCNNATWAIGEIAIKLGSDTSAYIPLILTQLIDIIN-RPNTPKTLL 811
Query: 2284 ENTAITIGRLGQCCGEELAPHISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGV 2463
ENTAITIGRLG C ++AP + +FVR C SLR+I+DN EK+SAF G+C MI +NP GV
Sbjct: 812 ENTAITIGRLGYVCPHDVAPMLQQFVRQWCTSLRSIRDNEEKDSAFRGMCQMITVNPAGV 871
Query: 2464 LNDFIFWCDAIASWTVPTDSLRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAFY 2643
+ DFIF+CDA+ASW P + L+ +F IL FK QVG NW F Q PP L ERL Y
Sbjct: 872 VQDFIFFCDAVASWVTPREDLKGMFQKILHGFKNQVGAENWKRFSDQFPPQLSERLHNMY 931
Query: 2644 QI 2649
+
Sbjct: 932 GV 933
>gi|5107636|pdb|1QBK|B Chain B, Structure Of The Karyopherin Beta2-Ran
Gppnhp Nuclear Transport Complex
Length = 890
Score = 833 bits (2153), Expect = 0.0
Identities = 429/891 (48%), Positives = 592/891 (66%), Gaps = 10/891 (1%)
Frame = +1
Query: 7 FQPDQHELEQVIQLLQHAHSTXXXXXXXXXXXXXXXXEHQKFCCYLVYILSDMKEMIDAT 186
++PD+ L+Q++QLL+ + S ++ F YL+++L+ +K D
Sbjct: 5 WKPDEQGLQQILQLLKESQSPDTTIQRTVQQKLEQLNQYPDFNNYLIFVLTKLKSE-DEP 63
Query: 187 SRSLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGDQEPLIRATVGIIVTTIVMEENM 366
+RSL+GL+LKNN++A + +P V F+++ CL +IGD PLIRATVGI++TTI + +
Sbjct: 64 TRSLSGLILKNNVKAHFQNFPNGVTDFIKSECLNNIGDSSPLIRATVGILITTIASKGEL 123
Query: 367 CDWPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYESEFL-RPI---MPKLLVFY 534
+WPDLL L ++L D EGA GALQK+ EDSA+ +S+ L RP+ +PK L F+
Sbjct: 124 QNWPDLLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVLDRPLNIXIPKFLQFF 183
Query: 535 EHHAAKMRALAMNCVNCILMVNNDPIDFAIDQFLTSLFARHNDNDEEVQKQLCRSLTLLL 714
+H + K+R+ A+ CVN ++ + ID F +LFA D + EV+K +CR+L LL
Sbjct: 184 KHSSPKIRSHAVACVNQFIISRTQALXLHIDSFTENLFALAGDEEPEVRKNVCRALVXLL 243
Query: 715 DTHIEKMMPHLPNVIEYIIKKTQDHNESIALEACEFWLSIAENSDICRTMVLPHLDKLIP 894
+ +++++PH N++EY +++TQD +E++ALEACEFWL++AE IC+ +++ HL KLIP
Sbjct: 244 EVRMDRLLPHXHNIVEYXLQRTQDQDENVALEACEFWLTLAEQP-ICKDVLVRHLPKLIP 302
Query: 895 VLLGSMRYSETDPALKAND--EDSSVPDREEDIKPRFHKSK----QHGLGGLVESXXXXX 1056
VL+ +YS+ D L D ED ++PD E+DI+PRFH+S+ QH G+ E
Sbjct: 303 VLVNGXKYSDIDIILLKGDVEEDETIPDSEQDIRPRFHRSRTVAQQHDEDGIEEEDDDDD 362
Query: 1057 XXXXXXXXXXWNIRRCSAASLDVLASIFGXXXXXXXXXXXXXXXMNDNWLVKESGILALG 1236
WN+R+CSAA+LDVLA+++ + W+VKESGIL LG
Sbjct: 363 EIDDDDTISDWNLRKCSAAALDVLANVYRDELLPHILPLLKELLFHHEWVVKESGILVLG 422
Query: 1237 AIAEGCMDGVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHIASDENFRQQFFKD 1416
AIAEGC G +P+L ELIP ++ + DKK LVRSITCWTLSRY+ + S + K
Sbjct: 423 AIAEGCXQGXIPYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPP--DTYLKP 480
Query: 1417 VLANLLRCSLDGNKKVQEAACSAFATLEEEAGEQLIPFLGEILDQLVKAFQCYQAKNLLI 1596
+ LL+ LD NK+VQEAACSAFATLEEEA +L+P+L ILD LV AF YQ KNLLI
Sbjct: 481 LXTELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLAYILDTLVFAFSKYQHKNLLI 540
Query: 1597 LYDAIGTLANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISAIVSAMGQS 1776
LYDAIGTLA+SVG L+ P Y+Q L PPL++KW L DEDK+LFPLLEC+S++ +A+
Sbjct: 541 LYDAIGTLADSVGHHLNKPEYIQXLXPPLIQKWNXLKDEDKDLFPLLECLSSVATALQSG 600
Query: 1777 FLPYIQPVFTRCCSLIEKCVQQNQQHIMAPDQVEAPETDFIIVALDLLSGLAESLPEHMD 1956
FLPY +PV+ RC +L++K + Q + PDQ EAP+ DF IVALDLLSGLAE L +++
Sbjct: 601 FLPYCEPVYQRCVNLVQKTLAQAXLNNAQPDQYEAPDKDFXIVALDLLSGLAEGLGGNIE 660
Query: 1957 PLVANSKLVELMLFCSLDVTPDVRQSCFALLGDLTKACPERVLPQSSNFIFFLAQNLDPS 2136
LVA S ++ L C D P+VRQS FALLGDLTKAC + V P ++F L NL+P
Sbjct: 661 QLVARSNILTLXYQCXQDKXPEVRQSSFALLGDLTKACFQHVKPCIADFXPILGTNLNPE 720
Query: 2137 KISVCNNAIWALGELALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLLENTAITIGRLG 2316
ISVCNNA WA+GE++++ G + +I ++ L+ +IN + N +TLLENTAITIGRLG
Sbjct: 721 FISVCNNATWAIGEISIQXGIEXQPYIPXVLHQLVEIIN-RPNTPKTLLENTAITIGRLG 779
Query: 2317 QCCGEELAPHISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGVLNDFIFWCDAI 2496
C +E+AP + +F+RP C SLRNI+DN EK+SAF G+C I++NP GV+ DFIF+CDA+
Sbjct: 780 YVCPQEVAPXLQQFIRPWCTSLRNIRDNEEKDSAFRGICTXISVNPSGVIQDFIFFCDAV 839
Query: 2497 ASWTVPTDSLRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAFYQI 2649
ASW P D LR F IL FK QVGD NW F Q P PL+ERL+AFY +
Sbjct: 840 ASWINPKDDLRDXFCKILHGFKNQVGDENWRRFSDQFPLPLKERLAAFYGV 890
>gi|31214900|ref|XP_315921.1| ENSANGP00000013476 [Anopheles gambiae]
gi|21299644|gb|EAA11789.1| ENSANGP00000013476 [Anopheles gambiae str.
PEST]
Length = 904
Score = 830 bits (2145), Expect = 0.0
Identities = 437/910 (48%), Positives = 598/910 (65%), Gaps = 27/910 (2%)
Frame = +1
Query: 1 MAFQPDQHELEQVIQLLQHAHSTXXXXXXXXXXXXXXXXEHQKFCCYLVYILSDMKEMID 180
M+++P L Q+I LL+ + ST ++ F YL+Y+L+ + D
Sbjct: 1 MSWEPQPDGLSQIITLLKQSQSTDNMVQRAVQLKLEELNQYPDFNNYLIYVLTKLTSE-D 59
Query: 181 ATSRSLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGDQEPLIRATVGIIVTTIVMEE 360
+RSL+GL+LKNNIR + + +++ CL ++GD PLIRAT GI++TTI +
Sbjct: 60 EPTRSLSGLILKNNIRIHGTELQPAIIEYIKQECLMALGDPSPLIRATAGILITTIANKG 119
Query: 361 NMCDWPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYESEFL-RPI---MPKLLV 528
+ +WP+LL TL +L D + EGA GALQK+ EDSAD +S L RP+ +PK L
Sbjct: 120 GLQNWPELLPTLCDMLDSQDYSVCEGAFGALQKICEDSADVLDSSALNRPLNIMIPKFLQ 179
Query: 529 FYEHHAAKMRALAMNCVNCILMVNNDPIDFAIDQFLTSLFARHNDNDEEVQKQLCRSLTL 708
F+ H + K+R+ A+ C+N ++ + ID F+ +LF +D+D EV+K +CR L +
Sbjct: 180 FFRHSSPKIRSNAIACINQFIINRTQALMVHIDTFIENLFHLSSDDDREVRKNVCRGLVM 239
Query: 709 LLDTHIEKMMPHLPNVIEYIIKKTQDHNESIALEACEFWLSIAENSDICRTMVLPHLDKL 888
LLD ++++MPH+ ++IEY++ +TQD +E+ +LEACEFWL++AE S IC+ ++ PHL +L
Sbjct: 240 LLDVRMDRLMPHMNSIIEYMLIRTQDSDET-SLEACEFWLTLAEQS-ICKEVLTPHLPRL 297
Query: 889 IPVLLGSMRYSETDPALKAND--EDSSVPDREEDIKPRFHKSKQH----GLGGLVESXXX 1050
+PVL+ M+YS+ D + D ED +PDREEDIKPRFHKS+ H LGG
Sbjct: 298 VPVLVRGMKYSDIDIIILKGDVEEDEMIPDREEDIKPRFHKSRTHTQKPSLGGGASGADG 357
Query: 1051 XXXXXXX-----------------XXXXXWNIRRCSAASLDVLASIFGXXXXXXXXXXXX 1179
WN+R+CSAA+LDVLA++F
Sbjct: 358 AVRAMEGNDDDEDIDDPYDEMDDDSNLSDWNLRKCSAAALDVLANVFKDDFLPILLPILK 417
Query: 1180 XXXMNDNWLVKESGILALGAIAEGCMDGVVPHLGELIPFMLAMMFDKKPLVRSITCWTLS 1359
++ W++KESGILALGAIAEGCM+G+VPHL ELIP+++ + DKK LVRSITCWTLS
Sbjct: 418 ETLFHEEWVIKESGILALGAIAEGCMNGMVPHLPELIPYLIVCLSDKKALVRSITCWTLS 477
Query: 1360 RYSSHIASDENFRQQFFKDVLANLLRCSLDGNKKVQEAACSAFATLEEEAGEQLIPFLGE 1539
RY+ + S + Q+ K ++ LL+ LD NK+VQEAACSAFATLEEEA +L+P+LG
Sbjct: 478 RYAHWVVSQPH--DQYLKPLMKELLKRILDANKRVQEAACSAFATLEEEACTELVPYLGF 535
Query: 1540 ILDQLVKAFQCYQAKNLLILYDAIGTLANSVGDALSHPVYVQMLMPPLMEKWERLSDEDK 1719
ILD LV AF+ YQ KNLLILYDAIGTLA+SVG L+ P Y+ MLMPPL+EKW L DEDK
Sbjct: 536 ILDTLVFAFRKYQHKNLLILYDAIGTLADSVGHHLNKPEYISMLMPPLIEKWNNLKDEDK 595
Query: 1720 ELFPLLECISAIVSAMGQSFLPYIQPVFTRCCSLIEKCVQQNQQHIMAPDQVEAPETDFI 1899
+LFPLLEC+S++ +A+ FLPY +PV+ RC SLI++ + Q+ +P Q E P+ DF+
Sbjct: 596 DLFPLLECLSSVATALHSGFLPYSEPVYRRCISLIQQTLNQDLASTTSPGQFEQPDKDFM 655
Query: 1900 IVALDLLSGLAESLPEHMDPLVANSKLVELMLFCSLDVTPDVRQSCFALLGDLTKACPER 2079
IVALDLLSGLAE L +++ LV++S +++L+ C D P+VRQS FALLGDLTKAC +
Sbjct: 656 IVALDLLSGLAEGLDCYIESLVSSSNIMQLLYQCMQDSMPEVRQSSFALLGDLTKACFQH 715
Query: 2080 VLPQSSNFIFFLAQNLDPSKISVCNNAIWALGELALKMGPAMKQFIGPIIEPLIVVINSQ 2259
V P ++F+ L NL+P ISVCNNA WA+GE+++K+ K +I ++ PLI +IN+
Sbjct: 716 VHPHIADFLPILGHNLNPEYISVCNNATWAIGEISIKLMEDTKPYIPMVLAPLIEIINN- 774
Query: 2260 QNMQRTLLENTAITIGRLGQCCGEELAPHISRFVRPCCYSLRNIKDNAEKESAFIGLCNM 2439
N +TLLENTAITIGRLG C E+AP + +FVR C SLRNI+DN EK+SAF G+C M
Sbjct: 775 TNTPKTLLENTAITIGRLGLVCPVEVAPSLQQFVRQWCSSLRNIRDNEEKDSAFRGMCQM 834
Query: 2440 INMNPVGVLNDFIFWCDAIASWTVPTDSLRVLFAGILQSFKQQVGDFNWNNFILQLPPPL 2619
I +NPVGV+ DFIF+CDA ASW P L + IL FK QVG+ NW F+ Q PP L
Sbjct: 835 ITVNPVGVVPDFIFFCDAAASWMTPKKDLHEMLQKILHGFKMQVGEENWARFVEQFPPQL 894
Query: 2620 RERLSAFYQI 2649
ERL+ Y I
Sbjct: 895 SERLAVMYSI 904
>gi|45504418|sp|O14787|TNP2_HUMAN Transportin 2 (Karyopherin beta-2b)
Length = 897
Score = 830 bits (2143), Expect = 0.0
Identities = 436/902 (48%), Positives = 596/902 (65%), Gaps = 19/902 (2%)
Frame = +1
Query: 1 MAFQPDQHELEQVIQLLQHAHSTXXXXXXXXXXXXXXXXEHQKFCCYLVYILSDMKEMID 180
M +QPD+ L+QV+QLL+ + S + F YL+++L+ +K D
Sbjct: 1 MDWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSE-D 59
Query: 181 ATSRSLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGDQEPLIRATVGIIVTTIVMEE 360
+RSL+GL+LKNN++A + +P V F++ CL +IGD LIRAT+GI++TTI +
Sbjct: 60 EPTRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKG 119
Query: 361 NMCDWPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYESEFL-RPI---MPKLLV 528
+ WP+LL L +L D EGA GALQK+ EDS++ +S+ L RP+ +PK L
Sbjct: 120 ELQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQ 179
Query: 529 FYEHHAAKMRALAMNCVNCILMVNNDPIDFAIDQFLTSLFARHNDNDEEVQKQLCRSLTL 708
F++H + K+R+ A+ CVN +M + ID F+ LFA D+D EV+K +CR+L +
Sbjct: 180 FFKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVM 239
Query: 709 LLDTHIEKMMPHLPNVIEYIIKKTQDHNESIALEACEFWLSIAENSDICRTMVLPHLDKL 888
LL+ I++++PH+ ++I+Y++++TQDH+E++ALEACEFWL++AE IC+ ++ HL +L
Sbjct: 240 LLEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQP-ICKEVLASHLVQL 298
Query: 889 IPVLLGSMRYSETDPALKAND--EDSSVPDREEDIKPRFHKSKQHGLGGLVE---SXXXX 1053
IP+L+ M+YSE D L D ED +VPD E+DIKPRFHKS+ L E
Sbjct: 299 IPILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDA 358
Query: 1054 XXXXXXXXXXXWNIRRCSAASLDVLASIFGXXXXXXXXXXXXXXXMNDNWLVKESGILAL 1233
WN+R+CSAA+LDVLA++F + W+VKESGIL L
Sbjct: 359 EDDDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVL 418
Query: 1234 GAIAEGCMDGVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHIASDENFRQQFFK 1413
GAIAEGCM G+VP+L ELIP ++ + DKK LVRSI CWTLSRY+ + S K
Sbjct: 419 GAIAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPP--DMHLK 476
Query: 1414 DVLANLLRCSLDGNKKVQEAACSAFATLEEEAGEQLIPFLGEILDQLVKAFQCYQAKNLL 1593
++ LL+ LDGNK+VQEAACSAFATLEEEA +L+P+L ILD LV AF YQ KNLL
Sbjct: 477 PLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLL 536
Query: 1594 ILYDAIGTLANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISAIVSAMGQ 1773
ILYDAIGTLA+SVG L+ P Y+Q LMPPL++KW L DEDK+LFPLLEC+S++ +A+
Sbjct: 537 ILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQS 596
Query: 1774 SFLPYIQPVFTRCCSLIEKCVQQNQQHIMAPDQVEAPETDFIIVALDLLSGLAESLPEHM 1953
FLPY +PV+ RC +L++K + Q + P+Q EAP+ DF+IVALDLL+GLAE L H+
Sbjct: 597 GFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLTGLAEGLGGHL 656
Query: 1954 DPLVANSKLVELMLFCSLDVTPDVRQSCFALLGDLTKACPERVLPQSSNFIFFLAQNLDP 2133
+ LVA S ++ L+ C D P+VRQS FALLGDLTKAC V P + F+ L NL+P
Sbjct: 657 EQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNP 716
Query: 2134 SKISVCNNAIWALGELALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLLENT------- 2292
ISVCNNA WA+GE+ ++MG M+ ++ ++ L+ +IN + N +TLLENT
Sbjct: 717 KFISVCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIIN-RPNTPKTLLENTGRLTSPS 775
Query: 2293 ---AITIGRLGQCCGEELAPHISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGV 2463
AITIGRLG C +E+AP + +F+RP C SLRNI+DN EK+SAF G+C MI +NP GV
Sbjct: 776 AIPAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIQDNEEKDSAFRGICMMIGVNPGGV 835
Query: 2464 LNDFIFWCDAIASWTVPTDSLRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAFY 2643
+ DFIF+CDA+ASW P D LR +F IL FK QVG+ NW F Q PP L+ERL+AFY
Sbjct: 836 VQDFIFFCDAVASWVSPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFY 895
Query: 2644 QI 2649
+
Sbjct: 896 GV 897
>gi|2440004|gb|AAB71349.1| karyopherin beta2b homolog [Homo sapiens]
Length = 887
Score = 829 bits (2142), Expect = 0.0
Identities = 431/892 (48%), Positives = 590/892 (65%), Gaps = 9/892 (1%)
Frame = +1
Query: 1 MAFQPDQHELEQVIQLLQHAHSTXXXXXXXXXXXXXXXXEHQKFCCYLVYILSDMKEMID 180
M +QPD+ L+QV+QLL+ + S + F YL+++L+ +K D
Sbjct: 1 MDWQPDEQGLQQVLQLLKDSQSPNTATHRIVRDKLKQLNQFPDFNNYLIFVLTRLKSE-D 59
Query: 181 ATSRSLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGDQEPLIRATVGIIVTTIVMEE 360
+RSL+GL+LKNN++A + +P V F++ CL +IGD LIRAT+GI++TTI +
Sbjct: 60 EPTRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKG 119
Query: 361 NMCDWPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYESEFL-RPI---MPKLLV 528
+ WP+LL L +L D EGA GALQK+ EDS++ +S+ L RP+ +PK L
Sbjct: 120 ELQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQ 179
Query: 529 FYEHHAAKMRALAMNCVNCILMVNNDPIDFAIDQFLTSLFARHNDNDEEVQKQLCRSLTL 708
F++H + K+R+ A+ CVN +M + ID F+ LFA D+D EV+K +CR+L +
Sbjct: 180 FFKHCSPKIRSHAIGCVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVM 239
Query: 709 LLDTHIEKMMPHLPNVIEYIIKKTQDHNESIALEACEFWLSIAENSDICRTMVLPHLDKL 888
LL+ I++++PH+ ++I+Y++++TQDH+E++ALEACEFWL++AE IC+ ++ HL +L
Sbjct: 240 LLEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQP-ICKEVLASHLVQL 298
Query: 889 IPVLLGSMRYSETDPALKAND--EDSSVPDREEDIKPRFHKSKQHGLGGLVE---SXXXX 1053
IP+L+ M+YSE D L D ED +VPD E+DIKPRFHKS+ L E
Sbjct: 299 IPILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDA 358
Query: 1054 XXXXXXXXXXXWNIRRCSAASLDVLASIFGXXXXXXXXXXXXXXXMNDNWLVKESGILAL 1233
WN+R+CSAA+LDVLA++F + W+VKESGIL L
Sbjct: 359 EDDDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVL 418
Query: 1234 GAIAEGCMDGVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHIASDENFRQQFFK 1413
GAIAEGCM G+VP+L ELIP ++ + DKK LVRSI CWTLSRY+ + S K
Sbjct: 419 GAIAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPP--DMHLK 476
Query: 1414 DVLANLLRCSLDGNKKVQEAACSAFATLEEEAGEQLIPFLGEILDQLVKAFQCYQAKNLL 1593
++ LL+ LDGNKKVQEAAC AFATLEE+A +L+P+L ILD LV AF YQ KNLL
Sbjct: 477 PLMTELLKRILDGNKKVQEAACIAFATLEEKACTELVPYLSYILDTLVFAFGKYQHKNLL 536
Query: 1594 ILYDAIGTLANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISAIVSAMGQ 1773
ILYDAIGTLA+SVG L+ P Y+Q LMPPL++KW L DEDK+LFPLLEC+S++ +A+
Sbjct: 537 ILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQS 596
Query: 1774 SFLPYIQPVFTRCCSLIEKCVQQNQQHIMAPDQVEAPETDFIIVALDLLSGLAESLPEHM 1953
FLPY +PV+ C +L++K + Q + P+Q EAP+ DF+IVALDL SGLAE L H+
Sbjct: 597 GFLPYCEPVYQCCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLFSGLAEGLGGHV 656
Query: 1954 DPLVANSKLVELMLFCSLDVTPDVRQSCFALLGDLTKACPERVLPQSSNFIFFLAQNLDP 2133
+ LVA S ++ L+ C D P+VRQS FA LGD TKAC V P + F+ L NL+P
Sbjct: 657 EQLVARSNIMTLLFQCMQDSMPEVRQSSFAFLGDFTKACSSHVKPCIAEFMPILGTNLNP 716
Query: 2134 SKISVCNNAIWALGELALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLLENTAITIGRL 2313
ISVCNNA WA+GE+ ++MG M+ ++ ++ L+ +IN + N +TLLENTAITIGRL
Sbjct: 717 EFISVCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIIN-RPNTPKTLLENTAITIGRL 775
Query: 2314 GQCCGEELAPHISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGVLNDFIFWCDA 2493
G C +E+AP + +F+RP C SLRNI+DN EK+SAF G+C MI +NP GV+ DFI +CDA
Sbjct: 776 GYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFILFCDA 835
Query: 2494 IASWTVPTDSLRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAFYQI 2649
+ASW P D LR +F IL FK QVG+ NW F Q PP L+ERL+AFY +
Sbjct: 836 VASWVSPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFYGV 887
>gi|2589204|gb|AAB83973.1| transportin2 [Homo sapiens]
Length = 896
Score = 825 bits (2131), Expect = 0.0
Identities = 436/902 (48%), Positives = 595/902 (65%), Gaps = 19/902 (2%)
Frame = +1
Query: 1 MAFQPDQHELEQVIQLLQHAHSTXXXXXXXXXXXXXXXXEHQKFCCYLVYILSDMKEMID 180
M +QPD+ L+QV+QLL+ + S + F YL+++L+ +K D
Sbjct: 1 MDWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSE-D 59
Query: 181 ATSRSLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGDQEPLIRATVGIIVTTIVMEE 360
+RSL+GL+LKNN++A + +P V F++ CL +IGD LIRAT+GI++TTI +
Sbjct: 60 EPTRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKG 119
Query: 361 NMCDWPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYESEFL-RPI---MPKLLV 528
+ WP+LL L +L D EGA GALQK+ EDS++ +S+ L RP+ +PK L
Sbjct: 120 ELQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQ 179
Query: 529 FYEHHAAKMRALAMNCVNCILMVNNDPIDFAIDQFLTSLFARHNDNDEEVQKQLCRSLTL 708
F++H + K+R+ A+ CVN +M + ID F+ LFA D+D EV+K +CR+L +
Sbjct: 180 FFKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVM 239
Query: 709 LLDTHIEKMMPHLPNVIEYIIKKTQDHNESIALEACEFWLSIAENSDICRTMVLPHLDKL 888
LL+ I++++PH+ ++I+Y++++TQDH+E++ALEACEFWL++AE IC+ ++ HL +L
Sbjct: 240 LLEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQP-ICKEVLASHLVQL 298
Query: 889 IPVLLGSMRYSETDPALKAND--EDSSVPDREEDIKPRFHKSKQHGLGGLVE---SXXXX 1053
IP+L+ M+YSE D L D ED +VPD E+DIKPRFHKS+ L E
Sbjct: 299 IPILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDA 358
Query: 1054 XXXXXXXXXXXWNIRRCSAASLDVLASIFGXXXXXXXXXXXXXXXMNDNWLVKESGILAL 1233
WN+R+CSAA+LDVLA++F + W+VKESGIL L
Sbjct: 359 EDDDDDDALSDWNLRKCSAAALDVLANVF-REELLPHLLPYQSLLFHPEWVVKESGILVL 417
Query: 1234 GAIAEGCMDGVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHIASDENFRQQFFK 1413
GAIAEGCM G+VP+L ELIP ++ + DKK LVRSI CWTLSRY+ + S K
Sbjct: 418 GAIAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPP--DMHLK 475
Query: 1414 DVLANLLRCSLDGNKKVQEAACSAFATLEEEAGEQLIPFLGEILDQLVKAFQCYQAKNLL 1593
++ LL+ LDGNK+VQEAACSAFATLEEEA +L+P+L ILD LV AF YQ KNLL
Sbjct: 476 PLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLL 535
Query: 1594 ILYDAIGTLANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISAIVSAMGQ 1773
ILYDAIGTLA+SVG L+ P Y+Q LMPPL++KW L DEDK+LFPLLEC+S++ +A+
Sbjct: 536 ILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQS 595
Query: 1774 SFLPYIQPVFTRCCSLIEKCVQQNQQHIMAPDQVEAPETDFIIVALDLLSGLAESLPEHM 1953
FLPY +PV+ RC +L++K + Q + P+Q EAP+ DF+IVALDLL+GLAE L H+
Sbjct: 596 GFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLTGLAEGLGGHL 655
Query: 1954 DPLVANSKLVELMLFCSLDVTPDVRQSCFALLGDLTKACPERVLPQSSNFIFFLAQNLDP 2133
+ LVA S ++ L+ C D P+VRQS FALLGDLTKAC V P + F+ L NL+P
Sbjct: 656 EQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNP 715
Query: 2134 SKISVCNNAIWALGELALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLLENT------- 2292
ISVCNNA WA+GE+ ++MG M+ ++ ++ L+ +IN + N +TLLENT
Sbjct: 716 KFISVCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIIN-RPNTPKTLLENTGRLTSPS 774
Query: 2293 ---AITIGRLGQCCGEELAPHISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGV 2463
AITIGRLG C +E+AP + +F+RP C SLRNI+DN EK+SAF G C MI +NP GV
Sbjct: 775 AIPAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIQDNEEKDSAFRGXCMMIGVNPGGV 834
Query: 2464 LNDFIFWCDAIASWTVPTDSLRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAFY 2643
+ DFIF+CDA+ASW P D LR +F IL FK QVG+ NW F Q PP L+ERL+AFY
Sbjct: 835 VQDFIFFCDAVASWVSPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFY 894
Query: 2644 QI 2649
+
Sbjct: 895 GV 896
>gi|17535479|ref|NP_496988.1| IMportin Beta (46.8 kD) (imb-2)
[Caenorhabditis elegans]
gi|7506340|pir||T23949 hypothetical protein R06A4.4b - Caenorhabditis
elegans
gi|3878861|emb|CAB05587.1| C. elegans IMB-2 protein (corresponding
sequence R06A4.4b) [Caenorhabditis elegans]
Length = 419
Score = 822 bits (2123), Expect = 0.0
Identities = 408/410 (99%), Positives = 408/410 (99%)
Frame = +1
Query: 1420 LANLLRCSLDGNKKVQEAACSAFATLEEEAGEQLIPFLGEILDQLVKAFQCYQAKNLLIL 1599
L LLRCSLDGNKKVQEAACSAFATLEEEAGEQLIPFLGEILDQLVKAFQCYQAKNLLIL
Sbjct: 10 LEQLLRCSLDGNKKVQEAACSAFATLEEEAGEQLIPFLGEILDQLVKAFQCYQAKNLLIL 69
Query: 1600 YDAIGTLANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISAIVSAMGQSF 1779
YDAIGTLANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISAIVSAMGQSF
Sbjct: 70 YDAIGTLANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISAIVSAMGQSF 129
Query: 1780 LPYIQPVFTRCCSLIEKCVQQNQQHIMAPDQVEAPETDFIIVALDLLSGLAESLPEHMDP 1959
LPYIQPVFTRCCSLIEKCVQQNQQHIMAPDQVEAPETDFIIVALDLLSGLAESLPEHMDP
Sbjct: 130 LPYIQPVFTRCCSLIEKCVQQNQQHIMAPDQVEAPETDFIIVALDLLSGLAESLPEHMDP 189
Query: 1960 LVANSKLVELMLFCSLDVTPDVRQSCFALLGDLTKACPERVLPQSSNFIFFLAQNLDPSK 2139
LVANSKLVELMLFCSLDVTPDVRQSCFALLGDLTKACPERVLPQSSNFIFFLAQNLDPSK
Sbjct: 190 LVANSKLVELMLFCSLDVTPDVRQSCFALLGDLTKACPERVLPQSSNFIFFLAQNLDPSK 249
Query: 2140 ISVCNNAIWALGELALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLLENTAITIGRLGQ 2319
ISVCNNAIWALGELALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLLENTAITIGRLGQ
Sbjct: 250 ISVCNNAIWALGELALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLLENTAITIGRLGQ 309
Query: 2320 CCGEELAPHISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGVLNDFIFWCDAIA 2499
CCGEELAPHISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGVLNDFIFWCDAIA
Sbjct: 310 CCGEELAPHISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGVLNDFIFWCDAIA 369
Query: 2500 SWTVPTDSLRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAFYQI 2649
SWTVPTDSLRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAFYQI
Sbjct: 370 SWTVPTDSLRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAFYQI 419
>gi|17137558|ref|NP_477368.1| CG7398-PA [Drosophila melanogaster]
gi|24659257|ref|NP_729154.1| CG7398-PB [Drosophila melanogaster]
gi|24659264|ref|NP_729155.1| CG7398-PC [Drosophila melanogaster]
gi|7295356|gb|AAF50674.1| CG7398-PA [Drosophila melanogaster]
gi|23094085|gb|AAN12089.1| CG7398-PB [Drosophila melanogaster]
gi|23094086|gb|AAN12090.1| CG7398-PC [Drosophila melanogaster]
Length = 893
Score = 811 bits (2095), Expect = 0.0
Identities = 427/900 (47%), Positives = 591/900 (65%), Gaps = 17/900 (1%)
Frame = +1
Query: 1 MAFQPDQHELEQVIQLLQHAHSTXXXXXXXXXXXXXXXXEHQKFCCYLVYILSDMKEMID 180
M ++P L+Q+I +L+ + S + F YL+Y+L+ +K D
Sbjct: 1 MTWEPQGEGLQQIIAILKESQSPDTATQMAVQMKLEEFNRYPDFNNYLIYVLTKLKTE-D 59
Query: 181 ATSRSLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGDQEPLIRATVGIIVTTIVMEE 360
+RSL+GL+LKNNIR ++ +++ CL+++GD PLIRATVGI++TTI
Sbjct: 60 EPTRSLSGLILKNNIRMHGTTLQPEIVEYIKHECLQAVGDASPLIRATVGILITTIASNG 119
Query: 361 NMCDWPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYESEFL-RPI---MPKLLV 528
+ +WP LL +L +L D + EGA ALQK+ EDSA+ +S L RP+ +PK L
Sbjct: 120 GLHNWPQLLPSLCEMLDNQDYNVCEGAFSALQKICEDSAEILDSAALNRPLNIMIPKFLE 179
Query: 529 FYEHHAAKMRALAMNCVNCILMVNNDPIDFAIDQFLTSLFARHNDNDEEVQKQLCRSLTL 708
+++H + K+R+ A+ C+N ++ + + ID F+ +LF +D D EV+K +C L +
Sbjct: 180 YFKHSSPKIRSHAIACINQFIINRSQALMLNIDSFIENLFHLSSDEDHEVRKNVCHGLVM 239
Query: 709 LLDTHIEKMMPHLPNVIEYIIKKTQDHNESIALEACEFWLSIAENSDICRTMVLPHLDKL 888
LL+ ++++MPH+ +IEY++ +TQD +E +ALEA EFWLS+AE S IC+ ++ P+L +L
Sbjct: 240 LLEVRMDRLMPHMSQIIEYMLLRTQDTDEGVALEASEFWLSLAEQS-ICKDVLAPYLAQL 298
Query: 889 IPVLLGSMRYSETDPAL-KAN-DEDSSVPDREEDIKPRFHKSKQH----------GLGGL 1032
PVL+ MRYSE D L K N +ED VPDREEDI+PRFHKS+ H G G
Sbjct: 299 APVLVRGMRYSEVDIILLKGNVEEDDMVPDREEDIRPRFHKSRAHTIRSTQEGGAGATGD 358
Query: 1033 VESXXXXXXXXXXXXXXXWNIRRCSAASLDVLASIFGXXXXXXXXXXXXXXXMNDNWLVK 1212
+ WN+R+CSAA+LDVLA++F + W++K
Sbjct: 359 DDDDEFEDGMDDDSSLSEWNLRKCSAAALDVLANVFREDCLPVVLPILKETLFHQEWVIK 418
Query: 1213 ESGILALGAIAEGCMDGVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHIASDEN 1392
ESG+LALGAIAEGCM G++ HL ELIP++++ + DKK LVRSITCWTLSRY++ + + +
Sbjct: 419 ESGVLALGAIAEGCMQGMIQHLPELIPYLISCLSDKKALVRSITCWTLSRYANWVVNQPH 478
Query: 1393 FRQQFFKDVLANLLRCSLDGNKKVQEAACSAFATLEEEAGEQLIPFLGEILDQLVKAFQC 1572
Q+ K ++ LL+ LD NK+VQEAACSAFATLEEEA +L+P+L IL LV AF
Sbjct: 479 --DQYLKPLMEELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLEYILKTLVFAFSK 536
Query: 1573 YQAKNLLILYDAIGTLANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISA 1752
YQ KNLLILYDA+GTLA+SVG L+ P Y+ +LMPPL++KW L D+DK+LFPLLEC+S+
Sbjct: 537 YQHKNLLILYDAVGTLADSVGHHLNKPQYIDILMPPLIDKWNLLKDDDKDLFPLLECLSS 596
Query: 1753 IVSAMGQSFLPYIQPVFTRCCSLIEKCVQQNQQHIMAPDQV-EAPETDFIIVALDLLSGL 1929
I +A+ FLPY PV+ RC SLIE+ + NQ+ + +Q + P+ + +IVALDLLSGL
Sbjct: 597 IATALQSGFLPYCDPVYRRCISLIEQTI--NQEMLCKQNQTYDHPDKERMIVALDLLSGL 654
Query: 1930 AESLPEHMDPLVANSKLVELMLFCSLDVTPDVRQSCFALLGDLTKACPERVLPQSSNFIF 2109
AE L H++ LVANS ++ L+ C DV P+VRQS FALLGDLTKAC V P ++F
Sbjct: 655 AEGLDRHIETLVANSNIMHLLYQCMQDVLPEVRQSSFALLGDLTKACFPHVHPFMADFFP 714
Query: 2110 FLAQNLDPSKISVCNNAIWALGELALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLLEN 2289
L QNL+P ISVCNNA WA+GE+ +K+G KQ+I ++ L ++IN + N +TLLEN
Sbjct: 715 ILGQNLNPDFISVCNNATWAIGEICMKLGEETKQYIRLVLSDLFIIIN-RPNTPKTLLEN 773
Query: 2290 TAITIGRLGQCCGEELAPHISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGVLN 2469
TAITIGRLG C E+AP++ FVR C SLR+I+DN EK+SAF G+C+MI +NP GV+
Sbjct: 774 TAITIGRLGYVCPVEVAPYLPEFVRQWCTSLRHIRDNDEKDSAFRGMCHMITVNPAGVVA 833
Query: 2470 DFIFWCDAIASWTVPTDSLRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAFYQI 2649
DFIF+CDAIASW P + L + IL FK QVG+ NW F+ Q PP L ERL+ Y I
Sbjct: 834 DFIFFCDAIASWVNPPEDLHQMIQKILHGFKTQVGEENWRRFVEQFPPTLAERLTTMYNI 893
>gi|27819795|gb|AAO24946.1| RE59670p [Drosophila melanogaster]
Length = 893
Score = 809 bits (2090), Expect = 0.0
Identities = 426/900 (47%), Positives = 590/900 (65%), Gaps = 17/900 (1%)
Frame = +1
Query: 1 MAFQPDQHELEQVIQLLQHAHSTXXXXXXXXXXXXXXXXEHQKFCCYLVYILSDMKEMID 180
M ++P L+Q+I +L+ + S + F YL+Y+L+ +K D
Sbjct: 1 MTWEPQGEGLQQIIAILKESQSPDTATKMAVQMKLEEFNRYPDFNNYLIYVLTKLKTE-D 59
Query: 181 ATSRSLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGDQEPLIRATVGIIVTTIVMEE 360
+RSL+GL+LKNNIR ++ +++ CL+++GD PLIRATVGI++TTI
Sbjct: 60 EPTRSLSGLILKNNIRMHGTTLQPEIVEYIKHECLQAVGDASPLIRATVGILITTIASNG 119
Query: 361 NMCDWPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYESEFL-RPI---MPKLLV 528
+ +WP LL +L +L D + EGA ALQK+ EDSA+ +S L RP+ +PK L
Sbjct: 120 GLHNWPQLLPSLCEMLDNQDYNVCEGAFSALQKICEDSAEILDSAALNRPLNIMIPKFLE 179
Query: 529 FYEHHAAKMRALAMNCVNCILMVNNDPIDFAIDQFLTSLFARHNDNDEEVQKQLCRSLTL 708
+++H + K+R+ A+ C+N ++ + + ID F+ +LF +D D EV+K +C L +
Sbjct: 180 YFKHSSPKIRSHAIACINQFIINRSQALMLNIDSFIENLFHLSSDEDHEVRKNVCHGLVM 239
Query: 709 LLDTHIEKMMPHLPNVIEYIIKKTQDHNESIALEACEFWLSIAENSDICRTMVLPHLDKL 888
LL+ ++++MPH+ +IEY++ +TQD +E +ALEA EFWLS+AE S IC+ ++ P+L +L
Sbjct: 240 LLEVRMDRLMPHMSQIIEYMLLRTQDTDEGVALEASEFWLSLAEQS-ICKDVLAPYLAQL 298
Query: 889 IPVLLGSMRYSETDPAL-KAN-DEDSSVPDREEDIKPRFHKSKQH----------GLGGL 1032
PVL+ MRYSE D L K N +ED VPDREEDI+P FHKS+ H G G
Sbjct: 299 APVLVRGMRYSEVDIILLKGNVEEDDMVPDREEDIRPHFHKSRAHTIRSTQEGGAGATGD 358
Query: 1033 VESXXXXXXXXXXXXXXXWNIRRCSAASLDVLASIFGXXXXXXXXXXXXXXXMNDNWLVK 1212
+ WN+R+CSAA+LDVLA++F + W++K
Sbjct: 359 DDDDEFEDGMDDDSSLSEWNLRKCSAAALDVLANVFREDCLPVVLPILKETLFHQEWVIK 418
Query: 1213 ESGILALGAIAEGCMDGVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHIASDEN 1392
ESG+LALGAIAEGCM G++ HL ELIP++++ + DKK LVRSITCWTLSRY++ + + +
Sbjct: 419 ESGVLALGAIAEGCMQGMIQHLPELIPYLISCLSDKKALVRSITCWTLSRYANWVVNQPH 478
Query: 1393 FRQQFFKDVLANLLRCSLDGNKKVQEAACSAFATLEEEAGEQLIPFLGEILDQLVKAFQC 1572
Q+ K ++ LL+ LD NK+VQEAACSAFATLEEEA +L+P+L IL LV AF
Sbjct: 479 --DQYLKPLMEELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLEYILKTLVFAFSK 536
Query: 1573 YQAKNLLILYDAIGTLANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISA 1752
YQ KNLLILYDA+GTLA+SVG L+ P Y+ +LMPPL++KW L D+DK+LFPLLEC+S+
Sbjct: 537 YQHKNLLILYDAVGTLADSVGHHLNKPQYIDILMPPLIDKWNLLKDDDKDLFPLLECLSS 596
Query: 1753 IVSAMGQSFLPYIQPVFTRCCSLIEKCVQQNQQHIMAPDQV-EAPETDFIIVALDLLSGL 1929
I +A+ FLPY PV+ RC SLIE+ + NQ+ + +Q + P+ + +IVALDLLSGL
Sbjct: 597 IATALQSGFLPYCDPVYRRCISLIEQTI--NQEMLCKQNQTYDHPDKERMIVALDLLSGL 654
Query: 1930 AESLPEHMDPLVANSKLVELMLFCSLDVTPDVRQSCFALLGDLTKACPERVLPQSSNFIF 2109
AE L H++ LVANS ++ L+ C DV P+VRQS FALLGDLTKAC V P ++F
Sbjct: 655 AEGLDRHIETLVANSNIMHLLYQCMQDVLPEVRQSSFALLGDLTKACFPHVHPFMADFFP 714
Query: 2110 FLAQNLDPSKISVCNNAIWALGELALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLLEN 2289
L QNL+P ISVCNNA WA+GE+ +K+G KQ+I ++ L ++IN + N +TLLEN
Sbjct: 715 ILGQNLNPDFISVCNNATWAIGEICMKLGEETKQYIRLVLSDLFIIIN-RPNTPKTLLEN 773
Query: 2290 TAITIGRLGQCCGEELAPHISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGVLN 2469
TAITIGRLG C E+AP++ FVR C SLR+I+DN EK+SAF G+C+MI +NP GV+
Sbjct: 774 TAITIGRLGYVCPVEVAPYLPEFVRQWCTSLRHIRDNDEKDSAFRGMCHMITVNPAGVVA 833
Query: 2470 DFIFWCDAIASWTVPTDSLRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAFYQI 2649
DFIF+CDAIASW P + L + IL FK QVG+ NW F+ Q PP L ERL+ Y I
Sbjct: 834 DFIFFCDAIASWVNPPEDLHQMIQKILHGFKTQVGEENWRRFVEQFPPTLAERLTTMYNI 893
>gi|47223870|emb|CAG06047.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 937
Score = 807 bits (2084), Expect = 0.0
Identities = 436/942 (46%), Positives = 596/942 (62%), Gaps = 59/942 (6%)
Frame = +1
Query: 1 MAFQPDQHELEQVIQLLQHAHSTXXXXXXXXXXXXXXXXEHQKFCCYLVYILSDMKEMID 180
M +QPD+ L+QV+QLL+ + S F YL+++L+ +K D
Sbjct: 1 MEWQPDEQGLQQVLQLLKDSQSPDTATQRAVQEKLEQLNHFPDFNNYLIFVLTSLKSE-D 59
Query: 181 ATSRSLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGDQEPLIRATVGIIVTTIVMEE 360
+RSL+GL+LKNN++A + +P +V F++ CL +IGD PLIRAT+GI++TTI +
Sbjct: 60 EPTRSLSGLILKNNVKAHYQSFPPNVADFIKRECLHNIGDPSPLIRATIGILITTIASKG 119
Query: 361 NMCDWPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYESEFL-RPI---MPKLLV 528
+ WP LL L +L D EG+ GALQK+ EDS++ +S+ L RP+ +PK L
Sbjct: 120 ELQTWPQLLPQLCNLLNSEDYNTCEGSFGALQKICEDSSELLDSDALNRPLNIMIPKFLQ 179
Query: 529 FYEHHAAKMRALAMNCVNCILMVNNDPIDFAIDQFLTSLFARHNDNDEEVQKQLCRSLTL 708
F++H + K+R+ A+ CVN ++ + +ID F+ SLFA D D EV+K +CR+L +
Sbjct: 180 FFKHCSPKIRSHAIACVNQFIIGRAQALMDSIDTFIESLFALAGDEDSEVRKNVCRALVM 239
Query: 709 LLDTHIEKMMPHLPNVIE-------------------------YIIKKTQDHNESIALEA 813
LL+ I++++PH+ ++I+ Y++++TQD +E++ALEA
Sbjct: 240 LLEVRIDRLIPHMHSIIQVSGGPDARPSFPPQQYFSAGLLRQQYMLQRTQDPDENVALEA 299
Query: 814 CEFWLSIAENSDICRTMVLPHLDKLIPVLLGSMRYSETDPALKAND--EDSSVPDREEDI 987
CEFWL++AE IC+ + HL +LIP+L+ M+YSE D L D ED ++PD E+DI
Sbjct: 300 CEFWLTLAEQP-ICKEALSGHLVQLIPILVNGMKYSEIDIILLKGDVEEDEAIPDSEQDI 358
Query: 988 KPRFHKSK----QHGLG-GLVESXXXXXXXXXXXXXXXWNIRRCSAASLDVLASIFGXXX 1152
KPRFHKS+ QH G G WN+R+CSAA+LDVLA++F
Sbjct: 359 KPRFHKSRTVTLQHEGGEGEEGEDIDEDEDDDDDALSDWNLRKCSAAALDVLANVFRDEL 418
Query: 1153 XXXXXXXXXXXXMNDNWLVKESGILALGAIAEGCMDGVVPHLGELIPFMLAMMFDKKPLV 1332
+ +W++KESGIL LGAIAEGCM G+VP+L ELIP ++ + DKK LV
Sbjct: 419 LPHLLPLLKGLLFHPDWVIKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCLCDKKALV 478
Query: 1333 RSITCWTLSRYSSHIASDENFRQQFFKDVLANLLRCSLDGNKKVQEAACSAFATLEEEAG 1512
RSI CWTLSRY+ + S K ++ LL+ LDGNK+VQEAACSAFATLEEEA
Sbjct: 479 RSIACWTLSRYAHWVVSQPP--DAHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEAC 536
Query: 1513 EQLIPFLGEILDQLVKAFQCYQAKNLLILYDAIGTLANSVGDALSHPVYVQMLMPPLMEK 1692
+L+P+L ILD LV AF YQ KNLLILYDAIGTLA+SVG L+ Y++ LMPPL+ K
Sbjct: 537 TELVPYLSFILDTLVFAFGKYQHKNLLILYDAIGTLADSVGHHLNQLEYIEKLMPPLIAK 596
Query: 1693 WERLSDEDKELFPLLECISAIVSAMGQSFLPYIQPVFTRCCSLIEKCVQQNQQHIMAPDQ 1872
W L DEDK+LFPLLEC+S++ +A+ FLPY +PV+ RC +L++K + Q + PDQ
Sbjct: 597 WNELKDEDKDLFPLLECLSSVATALQNGFLPYCEPVYQRCVTLVQKTLAQAMMYSQQPDQ 656
Query: 1873 VEAPETDFIIVALDLLSGLAESLPEHMDPLVANSKLVELMLFCSLDVTPDVRQSCFALLG 2052
EAP+ DF+IVALDLLSGLAE L H+D LVA S ++ L+ C D P+VRQS FALLG
Sbjct: 657 YEAPDKDFMIVALDLLSGLAEGLGGHVDSLVARSNIMTLLFQCMQDTMPEVRQSSFALLG 716
Query: 2053 DLTKACPERVLPQSSNFIFFLAQNLDPSKISVCNNAIWALGELALKMGPA---------- 2202
DLTKAC V P + F+ L NL+P ISVCNNA WA+GE+ ++MG A
Sbjct: 717 DLTKACFPHVKPCIAEFMPILGTNLNPEFISVCNNATWAIGEICMQMGGANMVYKCVFTL 776
Query: 2203 -------------MKQFIGPIIEPLIVVINSQQNMQRTLLENTAITIGRLGQCCGEELAP 2343
M+ +I ++ L+ +IN + N +TLLENTAITIGRLG C +E+A
Sbjct: 777 TGGSAGSLCSGVEMQPYIAMVLNQLVEIIN-RPNTPKTLLENTAITIGRLGYVCPQEVAS 835
Query: 2344 HISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGVLNDFIFWCDAIASWTVPTDS 2523
+ +F+RP C SLRNI+DN EK+SAF G+C MI +NP GV+ DFIF+CDA+ASW P D
Sbjct: 836 MLPQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWVNPKDD 895
Query: 2524 LRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAFYQI 2649
LR +F IL FK+QVG+ NW F Q PP L+ERL+A Y +
Sbjct: 896 LRDMFYKILHGFKEQVGEENWQQFSEQFPPLLKERLAACYGV 937
>gi|3293342|gb|AAC25708.1| transportin; TRN [Drosophila melanogaster]
Length = 893
Score = 803 bits (2074), Expect = 0.0
Identities = 424/900 (47%), Positives = 589/900 (65%), Gaps = 17/900 (1%)
Frame = +1
Query: 1 MAFQPDQHELEQVIQLLQHAHSTXXXXXXXXXXXXXXXXEHQKFCCYLVYILSDMKEMID 180
M ++P L+Q+I +L+ + S + F YL+Y+L+ +K D
Sbjct: 1 MTWEPQGEGLQQIIAILKESQSPDTATQMAVQMKLEEFNRYPDFNNYLIYVLTKLKTE-D 59
Query: 181 ATSRSLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGDQEPLIRATVGIIVTTIVMEE 360
+RSL+GL+LKNNIR ++ +++ CL+++GD PLIRATVGI++TTI
Sbjct: 60 EPTRSLSGLILKNNIRMHGTTLQPEIVEYIKHECLQAVGDSSPLIRATVGILITTIASNG 119
Query: 361 NMCDWPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYESEFL-RPI---MPKLLV 528
+ +WP LL +L +L D + EGA ALQK+ EDSA+ +S L RP+ +PK L
Sbjct: 120 GLHNWPQLLPSLCEMLDNQDYNVCEGAFSALQKICEDSAEILDSAALNRPLNIMIPKFLE 179
Query: 529 FYEHHAAKMRALAMNCVNCILMVNNDPIDFAIDQFLTSLFARHNDNDEEVQKQLCRSLTL 708
+++H + K+R+ A+ C+N ++ + + ID F+ +LF +D D EV+K +C L +
Sbjct: 180 YFKHSSPKIRSHAIACINQFIINRSQALMLNIDSFIENLFHLSSDEDHEVRKNVCHGLVM 239
Query: 709 LLDTHIEKMMPHLPNVIEYIIKKTQDHNESIALEACEFWLSIAENSDICRTMVLPHLDKL 888
LL ++++MPH+ +IEY++ +TQD +E +ALEA EFWLS+AE S IC+ ++ P+L +L
Sbjct: 240 LLKVRMDRLMPHMSQIIEYMLLRTQDTDEGVALEASEFWLSLAEQS-ICKDVLAPYLAQL 298
Query: 889 IPVLLGSMRYSETDPAL-KAN-DEDSSVPDREEDIKPRFHKSKQH----------GLGGL 1032
PVL+ MRYSE D L K N +ED VPDREEDI+PRFHKS+ H G G
Sbjct: 299 APVLVRGMRYSEVDIILLKGNVEEDDMVPDREEDIRPRFHKSRAHTIRSTQEGGAGATGD 358
Query: 1033 VESXXXXXXXXXXXXXXXWNIRRCSAASLDVLASIFGXXXXXXXXXXXXXXXMNDNWLVK 1212
+ WN+R+CSAA+LDVLA++F + W++K
Sbjct: 359 DDDDEFEDGMDDDSSLSEWNLRKCSAAALDVLANVFREDCLPIVLPILKETLFHQEWVIK 418
Query: 1213 ESGILALGAIAEGCMDGVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHIASDEN 1392
ESG+LALGAIAEGCM G++ HL ELIP++++ + DKK LVRSITCWTLSRY++ + + +
Sbjct: 419 ESGVLALGAIAEGCMQGMIQHLPELIPYLISCLSDKKALVRSITCWTLSRYANWVVNQPH 478
Query: 1393 FRQQFFKDVLANLLRCSLDGNKKVQEAACSAFATLEEEAGEQLIPFLGEILDQLVKAFQC 1572
Q+ K ++ LL+ LD NK+VQEAACSAFATLEEEA +L+P+L IL LV AF
Sbjct: 479 --DQYLKPLMEELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLEYILKTLVFAFSK 536
Query: 1573 YQAKNLLILYDAIGTLANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISA 1752
YQ KNLLILYDA+G+LA+SVG L+ P Y+ +LM P+++KW L D+DK+LFPLLEC+S+
Sbjct: 537 YQHKNLLILYDAVGSLADSVGHHLNKPQYIDILMLPIIDKWNLLKDDDKDLFPLLECLSS 596
Query: 1753 IVSAMGQSFLPYIQPVFTRCCSLIEKCVQQNQQHIMAPDQV-EAPETDFIIVALDLLSGL 1929
I +A+ FLPY PV+ RC SLIE+ + NQ+ + +Q + P+ + +IVALDLLSGL
Sbjct: 597 IATALQSGFLPYCDPVYRRCISLIEQTI--NQEMLCKQNQTYDHPDKERMIVALDLLSGL 654
Query: 1930 AESLPEHMDPLVANSKLVELMLFCSLDVTPDVRQSCFALLGDLTKACPERVLPQSSNFIF 2109
AE L H++ LVANS ++ L+ C DV P+VRQS FALLGDLTKAC V P ++F
Sbjct: 655 AEGLDRHIETLVANSNIMHLLYQCMQDVLPEVRQSSFALLGDLTKACFPHVHPFMADFFP 714
Query: 2110 FLAQNLDPSKISVCNNAIWALGELALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLLEN 2289
L QNL+P ISVCNNA WA+GE+ +K+G KQ+I ++ L ++IN + N +TLLEN
Sbjct: 715 ILGQNLNPDFISVCNNATWAIGEICMKLGEETKQYIRLVLSDLFIIIN-RPNTPKTLLEN 773
Query: 2290 TAITIGRLGQCCGEELAPHISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGVLN 2469
TAITIGRLG C E+AP++ FVR C SLR+I+DN EK+SAF G+C+MI +NP GV+
Sbjct: 774 TAITIGRLGYVCPVEVAPYLPEFVRQWCTSLRHIRDNDEKDSAFRGMCHMITVNPAGVVA 833
Query: 2470 DFIFWCDAIASWTVPTDSLRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAFYQI 2649
DFIF+CDAIASW P + L + IL FK QVG+ NW F+ Q PP L ERL+ Y I
Sbjct: 834 DFIFFCDAIASWVNPPEDLHQMIQKILHGFKTQVGEENWCRFVEQFPPTLAERLTTMYNI 893
>gi|34853468|ref|XP_219500.2| similar to karyopherin beta 2; importin
beta 2; transportin; M9 region interaction protein
[Rattus norvegicus]
Length = 918
Score = 791 bits (2044), Expect = 0.0
Identities = 421/936 (44%), Positives = 592/936 (62%), Gaps = 55/936 (5%)
Frame = +1
Query: 7 FQPDQHELEQVIQLLQHAHSTXXXXXXXXXXXXXXXXEHQKFCCYLVYILSDMKEMIDAT 186
++PD+ L+Q++QLL+ + S ++ F YL+++L+ +K D
Sbjct: 13 WKPDEQGLQQILQLLKESQSPDTTIQRTVQQKLEQLNQYPDFNNYLIFVLTKLKSE-DEP 71
Query: 187 SRSLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGDQEPLIRATVGIIVTTIVMEENM 366
+RSL+GL+LKNN++A + +P V F+++ CL +IGD PLIRATVGI++TTI + +
Sbjct: 72 TRSLSGLILKNNVKAHFQNFPNGVTDFIKSECLNNIGDSSPLIRATVGILITTIASKGEL 131
Query: 367 CDWPDLLDTLATVLMQPD------------------------------------------ 420
+WPDLL L ++L D
Sbjct: 132 QNWPDLLPKLCSLLDSEDYNTYRISQSSTGQPRMSPRDPTSFLLSGRVNVILGQKQLDAL 191
Query: 421 ---ELMQEGALGALQKVFEDSADRYESEFL-RPI---MPKLLVFYEHHAAKMRALAMNCV 579
+ EGA GALQK+ EDSA+ +S+ L RP+ +PK L F++H + K+R+ A+ CV
Sbjct: 192 ALKQHTLEGAFGALQKICEDSAEILDSDVLDRPLNIMIPKFLQFFKHSSPKIRSHAVACV 251
Query: 580 NCILMVNNDPIDFAIDQFLTSLFARHNDNDEEVQKQLCRSLTLLLDTHIEKMMPHLPNVI 759
N ++ + ID F+ +LFA D + EV+K +CR+L +LL+ +++++PH+ N++
Sbjct: 252 NQFIISRTQALMLHIDSFIENLFALAGDEEAEVRKNVCRALVMLLEVRMDRLLPHMHNIV 311
Query: 760 EYIIKKTQDHNESIALEACEFWLSIAENSDICRTMVLPHLDKLIPVLLGSMRYSETDPAL 939
EY++++TQD +E++ALEACEFWL++AE IC+ +++ HL KLIPVL+ M+YS+ D L
Sbjct: 312 EYMLQRTQDQDENVALEACEFWLTLAEQP-ICKDVLVRHLPKLIPVLVNGMKYSDIDIIL 370
Query: 940 KAND--EDSSVPDREEDIKPRFHKSK----QHGLGGLVESXXXXXXXXXXXXXXXWNIRR 1101
D ED ++PD E+DI+PRFH+S+ QH G+ E WN+R+
Sbjct: 371 LKGDVEEDEAIPDSEQDIRPRFHRSRTVAQQHEEDGIEEDDDDDDEIDDDDTISDWNLRK 430
Query: 1102 CSAASLDVLASIFGXXXXXXXXXXXXXXXMNDNWLVKESGILALGAIAEGCMDGVVPHLG 1281
CSAA+LDVLA+++ + W+VKESGIL LGAIAEGCM G++P+L
Sbjct: 431 CSAAALDVLANVYRDELLPHILPLLKELLFHHEWVVKESGILVLGAIAEGCMQGMIPYLP 490
Query: 1282 ELIPFMLAMMFDKKPLVRSITCWTLSRYSSHIASDENFRQQFFKDVLANLLRCSLDGNKK 1461
ELIP ++ + DKK LVRSITCWTLSRY+ + S + K ++ LL+ LD NK+
Sbjct: 491 ELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPP--DTYLKPLMTELLKRILDSNKR 548
Query: 1462 VQEAACSAFATLEEEAGEQLIPFLGEILDQLVKAFQCYQAKNLLILYDAIGTLANSVGDA 1641
VQEAACSAFATLEEEA +L+P+L ILD LV AF YQ KNLLILYDAIGTLA+SVG
Sbjct: 549 VQEAACSAFATLEEEACTELVPYLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHH 608
Query: 1642 LSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISAIVSAMGQSFLPYIQPVFTRCCSL 1821
L+ P Y+QMLMPPL++KW L DEDK+LFPLLEC+S++ +A+ FLPY +PV+ RC +L
Sbjct: 609 LNKPEYIQMLMPPLIQKWNMLKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVNL 668
Query: 1822 IEKCVQQNQQHIMAPDQVEAPETDFIIVALDLLSGLAESLPEHMDPLVANSKLVELMLFC 2001
++K + Q + P+Q EAP+ DF+IVALDLLSGLAE L +++ LVA S ++ LM C
Sbjct: 669 VQKTLAQAMLNNAQPEQYEAPDKDFMIVALDLLSGLAEGLGGNIEQLVARSNILTLMYQC 728
Query: 2002 SLDVTPDVRQSCFALLGDLTKACPERVLPQSSNFIFFLAQNLDPSKISVCNNAIWALGEL 2181
D P+VRQS FALLGDLTKAC + V P ++F+ L NL+P ISVCNNA WA+GE+
Sbjct: 729 MQDKMPEVRQSSFALLGDLTKACFQHVKPCIADFMPILGTNLNPEFISVCNNATWAIGEI 788
Query: 2182 ALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLLENTAITIGRLGQCCGEELAPHISRFV 2361
+++MG M+ +I ++ L+ +IN + N +TLLENTAITIGRLG C +E+AP + +F+
Sbjct: 789 SIQMGIEMQPYIPMVLHQLVEIIN-RPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFI 847
Query: 2362 RPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGVLNDFIFWCDAIASWTVPTDSLRVLFA 2541
RP C SLRNI+DN EK+SAF G+C MI++NP GV+
Sbjct: 848 RPWCTSLRNIRDNEEKDSAFRGICTMISVNPSGVIQ------------------------ 883
Query: 2542 GILQSFKQQVGDFNWNNFILQLPPPLRERLSAFYQI 2649
IL FK QVGD NW F Q P PL+ERL+AFY +
Sbjct: 884 -ILHGFKNQVGDENWRRFSDQFPLPLKERLAAFYGV 918
>gi|50761696|ref|XP_424806.1| PREDICTED: similar to transportin 1;
karyopherin (importin) beta 2; importin beta 2; M9 region
interaction protein [Gallus gallus]
Length = 1108
Score = 692 bits (1785), Expect = 0.0
Identities = 348/664 (52%), Positives = 464/664 (69%), Gaps = 6/664 (0%)
Frame = +1
Query: 622 IDQFLTSLFARHNDNDEEVQKQLCRSLTLLLDTHIEKMMPHLPNVIEYIIKKTQDHNESI 801
ID F+ +LFA D + EV+K +CR+L +LL+ +++++PH+ +++EY++ +TQD +E++
Sbjct: 3 IDAFIENLFALATDEEPEVRKNVCRALVMLLEVRMDRLLPHMISIVEYMLLRTQDQDENV 62
Query: 802 ALEACEFWLSIAENSDICRTMVLPHLDKLIPVLLGSMRYSETDPALKAND--EDSSVPDR 975
ALEACEFWL++AE IC+ ++ HL KLIPVL+ M+YSE D L D ED ++PD
Sbjct: 63 ALEACEFWLTLAEQP-ICKDVLCRHLTKLIPVLVNGMKYSEIDIILLKGDVEEDEAIPDS 121
Query: 976 EEDIKPRFHKSK----QHGLGGLVESXXXXXXXXXXXXXXXWNIRRCSAASLDVLASIFG 1143
E+DI+PRFH+S+ +H G+ + WN+R+CSAA+LDVLA++F
Sbjct: 122 EQDIRPRFHRSRTVAQKHEEDGIEDRDDDDDEIDDDDAISDWNLRKCSAAALDVLANVFR 181
Query: 1144 XXXXXXXXXXXXXXXMNDNWLVKESGILALGAIAEGCMDGVVPHLGELIPFMLAMMFDKK 1323
+ W+VKESGIL LGAIAEGCM G++P+L ELIP ++ + DKK
Sbjct: 182 DELLPHILPLLKELLFHPEWVVKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDKK 241
Query: 1324 PLVRSITCWTLSRYSSHIASDENFRQQFFKDVLANLLRCSLDGNKKVQEAACSAFATLEE 1503
LVRSITCWTLSRY+ + S + K ++ LL+ LD NK+VQEAACSAFATLEE
Sbjct: 242 ALVRSITCWTLSRYAHWVVSQPP--DTYLKPLMTELLQRILDSNKRVQEAACSAFATLEE 299
Query: 1504 EAGEQLIPFLGEILDQLVKAFQCYQAKNLLILYDAIGTLANSVGDALSHPVYVQMLMPPL 1683
EA +L+P+L ILD LV AF YQ KNLLILYDAIGTLA+SVG L+ P Y+QMLMPPL
Sbjct: 300 EACTELVPYLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPEYIQMLMPPL 359
Query: 1684 MEKWERLSDEDKELFPLLECISAIVSAMGQSFLPYIQPVFTRCCSLIEKCVQQNQQHIMA 1863
+ KW L DEDK+LFPLLEC+S++ +A+ FLPY +PV+ RC +L++K + Q H
Sbjct: 360 IHKWNMLKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVNLVQKTLAQAMLHNAQ 419
Query: 1864 PDQVEAPETDFIIVALDLLSGLAESLPEHMDPLVANSKLVELMLFCSLDVTPDVRQSCFA 2043
PDQ EAP+ DF+IVALDLLSGLAE L +++ LVA S ++ LM C D P+VRQS FA
Sbjct: 420 PDQYEAPDKDFMIVALDLLSGLAEGLGGNIEQLVARSNILTLMYQCMQDKMPEVRQSSFA 479
Query: 2044 LLGDLTKACPERVLPQSSNFIFFLAQNLDPSKISVCNNAIWALGELALKMGPAMKQFIGP 2223
LLGDLTKAC + V P ++F+ L NL+P ISVCNNA WA+GE++++MG M+ +I
Sbjct: 480 LLGDLTKACFQHVKPCIADFMPILGTNLNPEFISVCNNATWAIGEISIQMGIEMQPYIPM 539
Query: 2224 IIEPLIVVINSQQNMQRTLLENTAITIGRLGQCCGEELAPHISRFVRPCCYSLRNIKDNA 2403
++ L+ +IN + N +TLLENTAITIGRLG C +E+AP + +F+RP C SLRNI+DN
Sbjct: 540 VLHQLVEIIN-RPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNE 598
Query: 2404 EKESAFIGLCNMINMNPVGVLNDFIFWCDAIASWTVPTDSLRVLFAGILQSFKQQVGDFN 2583
EK+SAF G+C MI +NP GV DFIF+CDA+ASW P D LR +F IL FK QVGD N
Sbjct: 599 EKDSAFRGICTMITVNPNGVFQDFIFFCDAVASWISPKDDLRDMFCKILHGFKNQVGDEN 658
Query: 2584 WNNF 2595
W F
Sbjct: 659 WRRF 662
>gi|24659272|ref|NP_648038.1| CG8219-PA [Drosophila melanogaster]
gi|23094087|gb|AAF50673.2| CG8219-PA [Drosophila melanogaster]
Length = 853
Score = 690 bits (1780), Expect = 0.0
Identities = 349/831 (41%), Positives = 528/831 (62%), Gaps = 2/831 (0%)
Frame = +1
Query: 163 MKEMIDATSRSLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGDQEPLIRATVGIIVT 342
++E + +RS++GL+LKNNIR + +++ CL+++GD P IR TVGI++T
Sbjct: 31 VQETENEATRSMSGLILKNNIRMHDITLQPEHLEYIKHQCLQAVGDSSPEIRGTVGILIT 90
Query: 343 TIVMEENMCDWPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYESEFLRPIMPKL 522
TI + +WP LL +L +L D + EGA ALQK+ EDSA E+ L ++PK
Sbjct: 91 TIASNIGLHNWPQLLPSLCEMLDNQDYNVCEGAFSALQKICEDSAGILENMPLNTMIPKF 150
Query: 523 LVFYEHHAAKMRALAMNCVNCILMVNNDPIDFAIDQFLTSLFARHNDNDEEVQKQLCRSL 702
L +++H + K+R+ A+ C+N ++ + + ID + +L +DND V+ +C +L
Sbjct: 151 LEYFKHSSPKIRSHAIACINQFIINRSQALMLNIDSLIQNLLDVPSDNDPAVRMNVCHAL 210
Query: 703 TLLLDTHIEKMMPHLPNVIEYIIKKTQDHNESIALEACEFWLSIAENSDICRTMVLPHLD 882
L+ I+ MMPH+ +IE I+ ++QD +E++AL+A EFWLS+ + + CR ++ P L
Sbjct: 211 VGLVGVRIDLMMPHMSQIIELILLRSQDADENVALQATEFWLSLGKQRN-CRDILSPILS 269
Query: 883 KLIPVLLGSMRYSETDPALKAND--EDSSVPDREEDIKPRFHKSKQHGLGGLVESXXXXX 1056
+L+PVL+ +Y+ETD L D ED PDR++DI PRFH S+ HG+ ++
Sbjct: 270 QLVPVLVSRTQYTETDIILLKGDVGEDDKEPDRQQDISPRFHMSRVHGISNELDENSDDD 329
Query: 1057 XXXXXXXXXXWNIRRCSAASLDVLASIFGXXXXXXXXXXXXXXXMNDNWLVKESGILALG 1236
N+R+CSA +LD+++ IFG + W++KESG++ALG
Sbjct: 330 MWDSAL-----NLRKCSACALDIISKIFGDVCLPLMLPILKEALFHQEWVIKESGVMALG 384
Query: 1237 AIAEGCMDGVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHIASDENFRQQFFKD 1416
AIAEGCM G++PHL ELIP+++ + DKKPLVRSITCWT R+ + + + ++ +
Sbjct: 385 AIAEGCMQGLIPHLPELIPYLITCLSDKKPLVRSITCWTFMRFPKWVLNQPH--DKYLEP 442
Query: 1417 VLANLLRCSLDGNKKVQEAACSAFATLEEEAGEQLIPFLGEILDQLVKAFQCYQAKNLLI 1596
++ LL+C LD NK+VQEAACSAF LEEEA QL+P+L +L V AF Y +NLLI
Sbjct: 443 LIEELLKCILDSNKRVQEAACSAFVALEEEACTQLVPYLENMLKTFVLAFSKYHQRNLLI 502
Query: 1597 LYDAIGTLANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISAIVSAMGQS 1776
+YD +G LA SVG L+ P Y+ +LMPPLM+KW + D+DK++ LLEC+S+I +A+ S
Sbjct: 503 MYDVVGLLAESVGHHLNKPQYIDILMPPLMDKWNLVKDDDKDIIYLLECLSSIATALQSS 562
Query: 1777 FLPYIQPVFTRCCSLIEKCVQQNQQHIMAPDQVEAPETDFIIVALDLLSGLAESLPEHMD 1956
FLPY V+ + S+IE+ + Q+ + P+ + +++ALDL+SGL E L ++
Sbjct: 563 FLPYCDSVYRKGISIIEETINQDMM-CKQSQSTDYPDKERMVIALDLVSGLIEGLQSLIE 621
Query: 1957 PLVANSKLVELMLFCSLDVTPDVRQSCFALLGDLTKACPERVLPQSSNFIFFLAQNLDPS 2136
PLVANSKL++L+ C DV P+VRQS FALLGDL+ AC +V P +++FI L QNL+PS
Sbjct: 622 PLVANSKLLQLLCQCMGDVMPEVRQSSFALLGDLSGACFSQVYPYTAHFILILVQNLNPS 681
Query: 2137 KISVCNNAIWALGELALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLLENTAITIGRLG 2316
+ VCNNA+WA+G++ +K+G K ++ ++ L++++N +Q++ + L N AIT+GRLG
Sbjct: 682 VVGVCNNAVWAIGQICVKLGEETKPYVRLLLSELMILMN-RQDIPKNLSRNAAITLGRLG 740
Query: 2317 QCCGEELAPHISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGVLNDFIFWCDAI 2496
C +E+AP++ F+R C LR D+ EK +F+G+C+MI NP GV+ DF+F+CDAI
Sbjct: 741 NACPDEVAPYLPEFLRQWCLLLRYAYDHDEKYLSFMGMCHMIRENPGGVVPDFLFFCDAI 800
Query: 2497 ASWTVPTDSLRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAFYQI 2649
ASW P LR + I++ FK Q G NW F+ + P PL RL Y I
Sbjct: 801 ASWDNPPQDLRQMIRRIIEGFKNQTGAENWLIFLGKFPQPLACRLIELYDI 851
>gi|21429774|gb|AAM50565.1| AT21921p [Drosophila melanogaster]
Length = 853
Score = 688 bits (1776), Expect = 0.0
Identities = 349/831 (41%), Positives = 528/831 (62%), Gaps = 2/831 (0%)
Frame = +1
Query: 163 MKEMIDATSRSLAGLLLKNNIRAKWNKYPQDVKFFVRTTCLKSIGDQEPLIRATVGIIVT 342
++E + +RS++GL+LKNNIR + +++ CL+++GD P IR TVGI++T
Sbjct: 31 VQETENEATRSMSGLILKNNIRMHDITLQPEHLEYIKHQCLQAVGDSSPEIRGTVGILIT 90
Query: 343 TIVMEENMCDWPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYESEFLRPIMPKL 522
TI + +WP LL +L +L D + EGA ALQK+ EDSA E+ L ++PK
Sbjct: 91 TIASNIGLHNWPQLLPSLCEMLDNQDYNVCEGAFSALQKICEDSAGILENMPLNTMIPKF 150
Query: 523 LVFYEHHAAKMRALAMNCVNCILMVNNDPIDFAIDQFLTSLFARHNDNDEEVQKQLCRSL 702
L +++H + K+R+ A+ C+N ++ + + ID + +L +DND V+ +C +L
Sbjct: 151 LEYFKHSSPKIRSHAIACINQFIINRSQALMLNIDSLIQNLLDVPSDNDPAVRMNVCHAL 210
Query: 703 TLLLDTHIEKMMPHLPNVIEYIIKKTQDHNESIALEACEFWLSIAENSDICRTMVLPHLD 882
L+ I+ MMPH+ +IE I+ ++QD +E++AL+A EFWLS+ + + CR ++ P L
Sbjct: 211 VGLVGVRIDLMMPHMSQIIELILLRSQDADENVALQATEFWLSLGKQRN-CRDILSPILS 269
Query: 883 KLIPVLLGSMRYSETDPALKAND--EDSSVPDREEDIKPRFHKSKQHGLGGLVESXXXXX 1056
+L+PVL+ +Y+ETD L D ED PDR++DI PRFH S+ HG+ ++
Sbjct: 270 QLVPVLVSRTQYTETDIILLKGDVGEDDKEPDRQQDISPRFHMSRVHGISNELDENSDDD 329
Query: 1057 XXXXXXXXXXWNIRRCSAASLDVLASIFGXXXXXXXXXXXXXXXMNDNWLVKESGILALG 1236
N+R+CSA +LD+++ IFG + W++KESG++ALG
Sbjct: 330 MWDSAC-----NLRKCSACALDIISKIFGDVCLPLMLPILKEALFHQEWVIKESGVMALG 384
Query: 1237 AIAEGCMDGVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHIASDENFRQQFFKD 1416
AIAEGCM G++PHL ELIP+++ + DKKPLVRSITCWT R+ + + + ++ +
Sbjct: 385 AIAEGCMQGLIPHLPELIPYLITCLSDKKPLVRSITCWTFMRFPKWVLNQPH--DKYLEP 442
Query: 1417 VLANLLRCSLDGNKKVQEAACSAFATLEEEAGEQLIPFLGEILDQLVKAFQCYQAKNLLI 1596
++ LL+C LD NK+VQEAACSAF LEEEA QL+P+L +L V AF Y +NLLI
Sbjct: 443 LIEELLKCILDSNKRVQEAACSAFVALEEEACTQLVPYLENMLKTFVLAFSKYHQRNLLI 502
Query: 1597 LYDAIGTLANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISAIVSAMGQS 1776
+YD +G LA+SVG L+ P Y+ +LMPPLM+KW + D+DK++ LLEC+S+I +A+ S
Sbjct: 503 MYDVVGLLADSVGHHLNKPQYIDILMPPLMDKWNLVKDDDKDIIYLLECLSSIATALQSS 562
Query: 1777 FLPYIQPVFTRCCSLIEKCVQQNQQHIMAPDQVEAPETDFIIVALDLLSGLAESLPEHMD 1956
FLPY V+ + S+IE+ + Q+ + P+ + +++ALDL+SGL E L ++
Sbjct: 563 FLPYCDSVYRKGISIIEETINQDMM-CKQSQSTDYPDKERMVIALDLVSGLIEGLQSLIE 621
Query: 1957 PLVANSKLVELMLFCSLDVTPDVRQSCFALLGDLTKACPERVLPQSSNFIFFLAQNLDPS 2136
PLVANSKL++L+ C DV P+VRQS FALLGDL+ AC +V P +++FI L QNL+PS
Sbjct: 622 PLVANSKLLQLLCQCMGDVMPEVRQSSFALLGDLSGACFSQVYPYTAHFILILVQNLNPS 681
Query: 2137 KISVCNNAIWALGELALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLLENTAITIGRLG 2316
+ VCNNA+WA+G++ +K+G K ++ ++ L++++N +Q++ + L N AIT+GRLG
Sbjct: 682 VVGVCNNAVWAIGQICVKLGEETKPYVRLLLSELMILMN-RQDIPKNLSRNAAITLGRLG 740
Query: 2317 QCCGEELAPHISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGVLNDFIFWCDAI 2496
C +++AP++ F+R C LR D+ EK +F+G+C MI NP GV+ DF+F+CDAI
Sbjct: 741 NACPDKVAPYLPEFLRQWCLLLRYAYDHDEKYLSFMGMCLMIRENPGGVVPDFLFFCDAI 800
Query: 2497 ASWTVPTDSLRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAFYQI 2649
ASW P LR + I++ FK Q G NW F+ Q P PL RL Y I
Sbjct: 801 ASWDNPPQDLRQMIRRIIEGFKNQTGAENWLIFLGQFPQPLACRLIELYDI 851
>gi|21618743|gb|AAH31571.1| Tnpo1 protein [Mus musculus]
Length = 618
Score = 652 bits (1681), Expect = 0.0
Identities = 333/622 (53%), Positives = 435/622 (69%), Gaps = 6/622 (0%)
Frame = +1
Query: 802 ALEACEFWLSIAENSDICRTMVLPHLDKLIPVLLGSMRYSETDPALKAND--EDSSVPDR 975
ALEACEFWL++AE IC+ +++ HL KLIPVL+ M+YS+ D L D ED ++PD
Sbjct: 1 ALEACEFWLTLAEQP-ICKDVLVRHLPKLIPVLVNGMKYSDIDIILLKGDVEEDETIPDS 59
Query: 976 EEDIKPRFHKSK----QHGLGGLVESXXXXXXXXXXXXXXXWNIRRCSAASLDVLASIFG 1143
E+DI+PRFH+S+ QH G+ E WN+R+CSAA+LDVLA+++
Sbjct: 60 EQDIRPRFHRSRTVAQQHEEDGIEEEDDDDDEIDDDDTISDWNLRKCSAAALDVLANVYR 119
Query: 1144 XXXXXXXXXXXXXXXMNDNWLVKESGILALGAIAEGCMDGVVPHLGELIPFMLAMMFDKK 1323
+ W+VKESGIL LGAIAEGCM G++P+L ELIP ++ + DKK
Sbjct: 120 DELLPHILPLLKELLFHHEWVVKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDKK 179
Query: 1324 PLVRSITCWTLSRYSSHIASDENFRQQFFKDVLANLLRCSLDGNKKVQEAACSAFATLEE 1503
LVRSITCWTLSRY+ + S + K ++ LL+ LD NK+VQEAACSAFATLEE
Sbjct: 180 ALVRSITCWTLSRYAHWVVSQPP--DTYLKPLMTELLKRILDSNKRVQEAACSAFATLEE 237
Query: 1504 EAGEQLIPFLGEILDQLVKAFQCYQAKNLLILYDAIGTLANSVGDALSHPVYVQMLMPPL 1683
EA +L+P+L ILD LV AF YQ KNLLILYDAIGTLA+SVG L+ P Y+QMLMPPL
Sbjct: 238 EACTELVPYLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPEYIQMLMPPL 297
Query: 1684 MEKWERLSDEDKELFPLLECISAIVSAMGQSFLPYIQPVFTRCCSLIEKCVQQNQQHIMA 1863
++KW L DEDK+LFPLLEC+S++ +A+ FLPY +PV+ RC +L++K + Q +
Sbjct: 298 IQKWNMLKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVNLVQKTLAQAMLNNAQ 357
Query: 1864 PDQVEAPETDFIIVALDLLSGLAESLPEHMDPLVANSKLVELMLFCSLDVTPDVRQSCFA 2043
P+Q EAP+ DF+IVALDLLSGLAE L +++ LVA S ++ LM C D P+VRQS FA
Sbjct: 358 PEQYEAPDKDFMIVALDLLSGLAEGLGGNIEQLVARSNILTLMYQCMQDKMPEVRQSSFA 417
Query: 2044 LLGDLTKACPERVLPQSSNFIFFLAQNLDPSKISVCNNAIWALGELALKMGPAMKQFIGP 2223
LLGDLTKAC + V P ++F+ L NL+P ISVCNNA WA+GE++++MG M+ +I
Sbjct: 418 LLGDLTKACFQHVKPCIADFMPILGTNLNPEFISVCNNATWAIGEISIQMGIEMQPYIPM 477
Query: 2224 IIEPLIVVINSQQNMQRTLLENTAITIGRLGQCCGEELAPHISRFVRPCCYSLRNIKDNA 2403
++ L+ +IN + N +TLLENTAITIGRLG C +E+AP + +F+RP C SLRNI+DN
Sbjct: 478 VLHQLVEIIN-RPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNE 536
Query: 2404 EKESAFIGLCNMINMNPVGVLNDFIFWCDAIASWTVPTDSLRVLFAGILQSFKQQVGDFN 2583
EK+SAF G+C MI++NP GV+ DFIF+CDA+ASW P D LR +F IL FK QVGD N
Sbjct: 537 EKDSAFRGICTMISVNPSGVIQDFIFFCDAVASWINPKDDLRDMFCKILHGFKNQVGDEN 596
Query: 2584 WNNFILQLPPPLRERLSAFYQI 2649
W F Q P PL+ERL+AFY +
Sbjct: 597 WRRFSDQFPLPLKERLAAFYGV 618
>gi|20151549|gb|AAM11134.1| LD12333p [Drosophila melanogaster]
Length = 642
Score = 647 bits (1670), Expect = 0.0
Identities = 338/648 (52%), Positives = 444/648 (68%), Gaps = 13/648 (2%)
Frame = +1
Query: 745 LPNVIEYIIKKTQDHNESIALEACEFWLSIAENSDICRTMVLPHLDKLIPVLLGSMRYSE 924
+ +IEY++ +TQD +E +ALEA EFWLS+AE S IC+ ++ P+L +L PVL+ MRYSE
Sbjct: 1 MSQIIEYMLLRTQDTDEGVALEASEFWLSLAEQS-ICKDVLAPYLAQLAPVLVRGMRYSE 59
Query: 925 TDPAL-KAN-DEDSSVPDREEDIKPRFHKSKQH----------GLGGLVESXXXXXXXXX 1068
D L K N +ED VPDREEDI+PRFHKS+ H G G +
Sbjct: 60 VDIILLKGNVEEDDMVPDREEDIRPRFHKSRAHTIRSTQEGGAGATGDDDDDEFEDGMDD 119
Query: 1069 XXXXXXWNIRRCSAASLDVLASIFGXXXXXXXXXXXXXXXMNDNWLVKESGILALGAIAE 1248
WN+R+CSAA+LDVLA++F + W++KESG+LALGAIAE
Sbjct: 120 DSSLSEWNLRKCSAAALDVLANVFREDCLPVVLPILKETLFHQEWVIKESGVLALGAIAE 179
Query: 1249 GCMDGVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHIASDENFRQQFFKDVLAN 1428
GCM G++ HL ELIP++++ + DKK LVRSITCWTLSRY++ + + + Q+ K ++
Sbjct: 180 GCMQGMIQHLPELIPYLISCLSDKKALVRSITCWTLSRYANWVVNQPH--DQYLKPLMEE 237
Query: 1429 LLRCSLDGNKKVQEAACSAFATLEEEAGEQLIPFLGEILDQLVKAFQCYQAKNLLILYDA 1608
LL+ LD NK+VQEAACSAFATLEEEA +L+P+L IL LV AF YQ KNLLILYDA
Sbjct: 238 LLKRILDSNKRVQEAACSAFATLEEEACTELVPYLEYILKTLVFAFSKYQHKNLLILYDA 297
Query: 1609 IGTLANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISAIVSAMGQSFLPY 1788
+GTLA+SVG L+ P Y+ +LMPPL++KW L D+DK+LFPLLEC+S+I +A+ FLPY
Sbjct: 298 VGTLADSVGHHLNKPQYIDILMPPLIDKWNLLKDDDKDLFPLLECLSSIATALQSGFLPY 357
Query: 1789 IQPVFTRCCSLIEKCVQQNQQHIMAPDQV-EAPETDFIIVALDLLSGLAESLPEHMDPLV 1965
PV+ RC SLIE+ + NQ+ + +Q + P+ + +IVALDLLSGLAE L H++ LV
Sbjct: 358 CDPVYRRCISLIEQTI--NQEMLCKQNQTYDHPDKERMIVALDLLSGLAEGLDRHIETLV 415
Query: 1966 ANSKLVELMLFCSLDVTPDVRQSCFALLGDLTKACPERVLPQSSNFIFFLAQNLDPSKIS 2145
ANS ++ L+ C DV P+VRQS FALLGDLTKAC V P ++F L QNL+P IS
Sbjct: 416 ANSNIMHLLYQCMQDVLPEVRQSSFALLGDLTKACFPHVHPFMADFFPILGQNLNPDFIS 475
Query: 2146 VCNNAIWALGELALKMGPAMKQFIGPIIEPLIVVINSQQNMQRTLLENTAITIGRLGQCC 2325
VCNNA WA+GE+ +K+G KQ+I ++ L ++IN + N +TLLENTAITIGRLG C
Sbjct: 476 VCNNATWAIGEICMKLGEETKQYIRLVLSDLFIIIN-RPNTPKTLLENTAITIGRLGYVC 534
Query: 2326 GEELAPHISRFVRPCCYSLRNIKDNAEKESAFIGLCNMINMNPVGVLNDFIFWCDAIASW 2505
E+AP++ FVR C SLR+I+DN EK+SAF G+C+MI +NP GV+ DFIF+CDAIASW
Sbjct: 535 PVEVAPYLPEFVRQWCTSLRHIRDNDEKDSAFRGMCHMITVNPAGVVADFIFFCDAIASW 594
Query: 2506 TVPTDSLRVLFAGILQSFKQQVGDFNWNNFILQLPPPLRERLSAFYQI 2649
P + L + IL FK QVG+ NW F+ Q PP L ERL+ Y I
Sbjct: 595 VNPPEDLHQMIQKILHGFKTQVGEENWRRFVEQFPPTLAERLTTMYNI 642