Homology by BLASTX
BLASTX 2.2.4 [Aug-26-2002]
Query= T09B9_1
(4807 letters)
Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
1,967,186 sequences; 661,712,633 total letters
Score E
Sequences producing significant alignments: (bits) Value
gi|17568541|ref|NP_509635.1| high Incidence of Males due to incr... 3150 0.0
gi|7499207|pir||T20992 hypothetical protein F15G9.4a - Caenorhab... 3091 0.0
gi|39596105|emb|CAE69741.1| Hypothetical protein CBG16014 [Caeno... 2310 0.0
gi|31083306|ref|NP_114141.1| hemicentin; fibulin 6 [Homo sapiens] 475 e-132
gi|14575679|gb|AAK68690.1| hemicentin [Homo sapiens] 472 e-131
gi|13872813|emb|CAC37630.1| fibulin-6 [Homo sapiens] 472 e-131
gi|38073489|ref|XP_136261.3| similar to hemicentin; fibulin 6 [M... 446 e-123
gi|47214649|emb|CAG05169.1| unnamed protein product [Tetraodon n... 441 e-121
gi|47222186|emb|CAG11612.1| unnamed protein product [Tetraodon n... 439 e-121
gi|34880529|ref|XP_222716.2| similar to hemicentin; fibulin 6 [R... 432 e-119
gi|41148814|ref|XP_175125.4| hemicentin-2 [Homo sapiens] 410 e-112
gi|16551993|dbj|BAB71216.1| unnamed protein product [Homo sapiens] 396 e-108
gi|39596128|emb|CAE69764.1| Hypothetical protein CBG16045 [Caeno... 382 e-104
gi|34853544|ref|XP_231135.2| similar to hypothetical protein [Ra... 377 e-102
gi|21739606|emb|CAD38854.1| hypothetical protein [Homo sapiens] 362 6e-98
gi|37623931|gb|AAP80789.2| cardiac titin N2BA isoform [Rattus no... 313 2e-83
gi|7512404|pir||I38346 elastic titin - human (fragment) >gnl|BL_... 311 1e-82
gi|17066105|emb|CAD12456.1| Titin [Homo sapiens] 311 1e-82
gi|50659088|ref|NP_596869.2| titin isoform N2-A; connectin; CMH9... 311 1e-82
gi|33413750|gb|AAN11323.1| cardiac titin [Canis familiaris] 310 2e-82
gi|47222185|emb|CAG11611.1| unnamed protein product [Tetraodon n... 295 7e-78
gi|47214568|emb|CAG13290.1| unnamed protein product [Tetraodon n... 269 6e-70
gi|48095560|ref|XP_392317.1| similar to ENSANGP00000018214 [Apis... 268 7e-70
gi|18390319|ref|NP_056234.1| adlican [Homo sapiens] >gnl|BL_ORD_... 265 8e-69
gi|38490688|ref|NP_849144.2| immunoglobulin superfamily, member ... 265 8e-69
gi|11359852|pir||T42633 connectin/titin - chicken (fragment) >gn... 264 1e-68
gi|50730336|ref|XP_416853.1| PREDICTED: similar to adlican [Gall... 260 2e-67
gi|39586313|emb|CAE66724.1| Hypothetical protein CBG12070 [Caeno... 249 5e-64
gi|1172451|sp|Q05793|PGBM_MOUSE Basement membrane-specific hepar... 248 1e-63
gi|25141314|ref|NP_491290.2| UNCoordinated locomotion UNC-89, PH... 246 5e-63
gi|31746683|gb|AAP68958.1| Uncoordinated protein 89, isoform b [... 246 5e-63
gi|38454276|ref|NP_942063.1| bone specific CMF608 [Rattus norveg... 244 2e-62
gi|38076522|ref|XP_143254.3| similar to bone specific CMF608 [Mu... 241 2e-61
gi|1160355|gb|AAB00542.1| UNC-89 235 9e-60
gi|539611|pir||A38096 perlecan precursor - human >gnl|BL_ORD_ID|... 234 1e-59
gi|24212664|sp|P98160|PGBM_HUMAN Basement membrane-specific hepa... 234 2e-59
gi|11602963|emb|CAC18534.1| heparan sulfate proteoglycan perleca... 234 2e-59
gi|7511618|pir||T29757 protein UNC-89 - Caenorhabditis elegans 232 6e-59
gi|7427517|ref|NP_005520.2| heparan sulfate proteoglycan 2; hepa... 230 2e-58
gi|34872189|ref|XP_233606.2| similar to Basement membrane-specif... 224 2e-56
gi|16551710|dbj|BAB71154.1| unnamed protein product [Homo sapiens] 221 1e-55
gi|24762491|ref|NP_611867.1| CG30171-PB [Drosophila melanogaster... 212 6e-53
gi|24586203|ref|NP_724542.1| CG17800-PC [Drosophila melanogaster... 208 1e-51
gi|8072217|gb|AAF71926.1| Dscam [Drosophila melanogaster] 207 3e-51
gi|24586205|ref|NP_724543.1| CG17800-PA [Drosophila melanogaster... 206 3e-51
gi|28573968|ref|NP_523649.5| CG17800-PD [Drosophila melanogaster... 206 6e-51
gi|24653966|ref|NP_725506.1| CG18255-PA [Drosophila melanogaster... 204 2e-50
gi|24653968|ref|NP_725507.1| CG18255-PC [Drosophila melanogaster... 204 2e-50
gi|47846181|emb|CAE51322.1| basement membrane-specific heparan s... 198 9e-49
gi|48095021|ref|XP_392224.1| similar to CG32387-PB [Apis mellifera] 193 3e-47
gi|47226798|emb|CAG06640.1| unnamed protein product [Tetraodon n... 192 7e-47
gi|200301|gb|AAA39912.1| basement membrane proteoglycan 191 1e-46
gi|31197929|ref|XP_307912.1| ENSANGP00000021854 [Anopheles gambi... 191 1e-46
gi|45552493|ref|NP_995769.1| CG17800-PE [Drosophila melanogaster... 191 2e-46
gi|47210289|emb|CAF90147.1| unnamed protein product [Tetraodon n... 189 6e-46
gi|39593042|emb|CAE64511.1| Hypothetical protein CBG09247 [Caeno... 188 1e-45
gi|25145902|ref|NP_741549.1| fibronectin, type III and protein k... 188 1e-45
gi|7498954|pir||T34416 hypothetical protein F12F3.2 - Caenorhabd... 188 1e-45
gi|24620457|gb|AAN61521.1| 301KDa_2 protein [Caenorhabditis eleg... 188 1e-45
gi|24620454|gb|AAN61518.1| 2MDa_2 protein [Caenorhabditis elegans] 188 1e-45
gi|24620456|gb|AAN61520.1| 301KDa_1 protein [Caenorhabditis eleg... 188 1e-45
gi|24620453|gb|AAN61517.1| 2MDa_1 protein [Caenorhabditis elegans] 188 1e-45
gi|25145904|ref|NP_741548.1| fibronectin, type III and protein k... 188 1e-45
gi|21751818|dbj|BAC04042.1| unnamed protein product [Homo sapiens] 185 1e-44
gi|48095869|ref|XP_392361.1| similar to CG30171-PB [Apis mellifera] 183 3e-44
gi|47229075|emb|CAG03827.1| unnamed protein product [Tetraodon n... 181 1e-43
gi|45580804|ref|NP_996024.1| CG33274-PA [Drosophila melanogaster... 181 2e-43
gi|50729979|ref|XP_416734.1| PREDICTED: similar to Down syndrome... 178 1e-42
gi|7512753|pir||T08678 hypothetical protein DKFZp564I1922.1 - hu... 177 3e-42
gi|47214648|emb|CAG05168.1| unnamed protein product [Tetraodon n... 176 4e-42
gi|47271220|gb|AAT27280.1| LP21844p [Drosophila melanogaster] 176 6e-42
gi|31213063|ref|XP_315475.1| ENSANGP00000021721 [Anopheles gambi... 176 6e-42
gi|27696508|gb|AAH31063.1| IGSF10 protein [Homo sapiens] 174 2e-41
gi|31199437|ref|XP_308666.1| ENSANGP00000011092 [Anopheles gambi... 174 2e-41
gi|48111627|ref|XP_396307.1| similar to CG31190-PB [Apis mellifera] 172 9e-41
gi|24158420|ref|NP_524643.2| CG7981-PA [Drosophila melanogaster]... 171 2e-40
gi|24655822|ref|NP_652705.1| CG1915-PC [Drosophila melanogaster]... 171 2e-40
gi|48096455|ref|XP_392460.1| similar to BMKETTIN [Apis mellifera] 171 2e-40
gi|8250181|emb|CAB93524.1| D-Titin [Drosophila melanogaster] 170 3e-40
gi|18252623|gb|AAL66361.1| roundabout-1 [Xenopus laevis] 169 6e-40
gi|24639352|ref|NP_726813.1| CG7981-PC [Drosophila melanogaster]... 169 6e-40
gi|24639356|ref|NP_726815.1| CG7981-PD [Drosophila melanogaster]... 169 6e-40
gi|18033452|gb|AAL57166.1| Down syndrome cell adhesion molecule ... 169 8e-40
gi|20521772|dbj|BAA86446.2| KIAA1132 protein [Homo sapiens] 169 8e-40
gi|2706875|dbj|BAA24032.1| NCAM-180 [Cynops pyrrhogaster] 168 1e-39
gi|21359935|ref|NP_065744.2| Down syndrome cell adhesion molecul... 168 1e-39
gi|2706876|dbj|BAA24033.1| NCAM-140 [Cynops pyrrhogaster] 168 1e-39
gi|19852060|gb|AAL99985.1| Down syndrome cell adhesion molecule-... 167 2e-39
gi|24659848|ref|NP_729224.1| CG32387-PB [Drosophila melanogaster... 167 2e-39
gi|24659853|ref|NP_729225.1| CG32387-PA [Drosophila melanogaster... 167 2e-39
gi|48129578|ref|XP_393308.1| similar to CG32387-PB [Apis mellifera] 166 5e-39
gi|47222572|emb|CAG02937.1| unnamed protein product [Tetraodon n... 166 7e-39
gi|31208927|ref|XP_313430.1| ENSANGP00000020211 [Anopheles gambi... 165 9e-39
gi|542688|pir||PN0568 connectin 3B - chicken (fragment) >gnl|BL_... 165 9e-39
gi|24371280|ref|NP_571556.1| roundabout homolog 1; roundabout (a... 165 1e-38
gi|40255314|ref|NP_443075.1| obscurin, cytoskeletal calmodulin a... 164 2e-38
gi|47219381|emb|CAG01544.1| unnamed protein product [Tetraodon n... 164 2e-38
gi|23450943|gb|AAN32613.1| Down syndrome cell adhesion molecule ... 164 2e-38
gi|38089814|ref|XP_356154.1| Down syndrome cell adhesion molecul... 163 3e-38
gi|16551976|dbj|BAB71212.1| unnamed protein product [Homo sapiens] 163 4e-38
gi|48476182|ref|NP_071765.2| roundabout, axon guidance receptor,... 162 6e-38
gi|50732147|ref|XP_418501.1| PREDICTED: similar to obscurin, cyt... 162 1e-37
gi|50760218|ref|XP_425808.1| PREDICTED: similar to Down syndrome... 162 1e-37
gi|24639358|ref|NP_726816.1| CG7981-PB [Drosophila melanogaster]... 160 3e-37
gi|42656654|ref|XP_031246.10| roundabout, axon guidance receptor... 160 3e-37
gi|47220212|emb|CAF98977.1| unnamed protein product [Tetraodon n... 160 3e-37
gi|24639354|ref|NP_726814.1| CG7981-PE [Drosophila melanogaster]... 160 3e-37
gi|49036496|sp|Q9HCK4|ROB2_HUMAN Roundabout homolog 2 precursor 160 3e-37
gi|10047201|dbj|BAB13394.1| KIAA1568 protein [Homo sapiens] 160 3e-37
gi|6946670|emb|CAB72285.1| EG:BACR25B3.10 [Drosophila melanogaster] 160 4e-37
gi|18700461|dbj|BAB85198.1| Titin-like protein [Bombyx mori] 159 5e-37
gi|22474516|dbj|BAC10620.1| Titin-like protein [Bombyx mori] 159 5e-37
gi|31201553|ref|XP_309724.1| ENSANGP00000012544 [Anopheles gambi... 159 8e-37
gi|47225054|emb|CAF97469.1| unnamed protein product [Tetraodon n... 158 1e-36
gi|23450945|gb|AAN32614.1| Down syndrome cell adhesion molecule ... 157 2e-36
gi|4506569|ref|NP_002932.1| roundabout 1 isoform a; roundabout 1... 157 2e-36
gi|19743806|ref|NP_598334.1| roundabout 1 isoform b; roundabout ... 157 2e-36
gi|7717377|emb|CAB90436.1| human CHD2-52 down syndrome cell adhe... 157 3e-36
gi|45827726|ref|NP_996770.1| Down syndrome cell adhesion molecul... 157 3e-36
gi|33469129|ref|NP_062286.1| roundabout homolog 1 [Mus musculus]... 157 3e-36
gi|18032392|gb|AAL56711.1| Down syndrome cell adhesion molecule ... 157 3e-36
gi|20127422|ref|NP_001380.2| Down syndrome cell adhesion molecul... 157 3e-36
gi|7512400|pir||T08851 Down syndrome cell adhesion protein 1 - h... 157 3e-36
gi|18859319|ref|NP_571708.1| roundabout homolog 2 [Danio rerio] ... 156 4e-36
gi|11559953|ref|NP_071524.1| roundabout homolog 1 [Rattus norveg... 156 4e-36
gi|34863083|ref|XP_236056.2| similar to rig-1 protein [Rattus no... 156 5e-36
gi|31212017|ref|XP_314993.1| ENSANGP00000021379 [Anopheles gambi... 156 5e-36
gi|34863302|ref|XP_236203.2| similar to Down syndrome cell adhes... 156 5e-36
gi|47227825|emb|CAG08988.1| unnamed protein product [Tetraodon n... 155 9e-36
gi|11544425|emb|CAC17584.1| bG153O3.1 (similar to C.elegans hemi... 155 9e-36
gi|31205013|ref|XP_311455.1| ENSANGP00000000600 [Anopheles gambi... 154 2e-35
gi|7106393|ref|NP_035378.1| roundabout homolog 3; retinoblastoma... 154 2e-35
gi|27884114|emb|CAD61245.1| SI:dZ249N21.1.1 (novel protein simil... 154 3e-35
gi|49036483|sp|Q7TPD3|ROB2_MOUSE Roundabout homolog 2 precursor 154 3e-35
gi|33244029|gb|AAH55333.1| Robo2 protein [Mus musculus] 154 3e-35
gi|26329151|dbj|BAC28314.1| unnamed protein product [Mus musculus] 153 3e-35
gi|45553395|ref|NP_996226.1| CG31190-PB [Drosophila melanogaster... 153 3e-35
gi|49036501|sp|Q9Z2I4|ROB3_MOUSE Roundabout homolog 3 precursor ... 153 4e-35
gi|34858708|ref|XP_230608.2| similar to sialoadhesin [Rattus nor... 153 4e-35
gi|50744908|ref|XP_419931.1| PREDICTED: similar to CG12002-PA [G... 152 6e-35
gi|30179887|sp|Q06561|UN52_CAEEL Basement membrane proteoglycan ... 152 8e-35
gi|50507819|emb|CAH04704.1| Hypothetical protein ZC101.2f [Caeno... 152 8e-35
gi|289722|gb|AAA28156.1| basement membrane proteoglycan 152 8e-35
gi|17536621|ref|NP_497046.1| basement membrane proteoglycan (2O9... 152 8e-35
gi|6164831|gb|AAF04558.1| Robo2 [Rattus norvegicus] 152 1e-34
gi|13626028|ref|NP_112451.1| Down syndrome cell adhesion molecul... 152 1e-34
gi|19424286|ref|NP_598271.1| Down syndrome cell adhesion molecul... 152 1e-34
gi|47224969|emb|CAF97384.1| unnamed protein product [Tetraodon n... 151 1e-34
gi|47227738|emb|CAG08901.1| unnamed protein product [Tetraodon n... 151 2e-34
gi|17530861|ref|NP_511090.1| CG1634-PA [Drosophila melanogaster]... 150 3e-34
gi|47227361|emb|CAF96910.1| unnamed protein product [Tetraodon n... 150 3e-34
gi|24640619|ref|NP_727274.1| CG1634-PB [Drosophila melanogaster]... 150 3e-34
gi|6760654|gb|AAC28614.2| neuroglian [Drosophila melanogaster] 149 6e-34
gi|103273|pir||A32579 neuroglian - fruit fly (Drosophila melanog... 149 6e-34
gi|6760653|gb|AAC28613.2| neuroglian [Drosophila melanogaster] 149 6e-34
gi|16758574|ref|NP_446198.1| contactin 5 [Rattus norvegicus] >gn... 149 8e-34
gi|13435353|ref|NP_076493.1| L1 cell adhesion molecule isoform 2... 149 8e-34
gi|4557707|ref|NP_000416.1| L1 cell adhesion molecule isoform 1 ... 149 8e-34
gi|31201725|ref|XP_309810.1| ENSANGP00000018214 [Anopheles gambi... 149 8e-34
gi|33354077|dbj|BAC81122.1| L1 cell adhesion molecule [Homo sapi... 149 8e-34
gi|28972103|dbj|BAC65505.1| mKIAA0230 protein [Mus musculus] 148 1e-33
gi|127857|sp|P13592|NCA2_HUMAN Neural cell adhesion molecule 1, ... 148 1e-33
gi|26341784|dbj|BAC34554.1| unnamed protein product [Mus musculus] 148 1e-33
gi|26349823|dbj|BAC38551.1| unnamed protein product [Mus musculus] 148 1e-33
gi|10834990|ref|NP_000606.1| neural cell adhesion molecule 1; an... 148 1e-33
gi|33354079|dbj|BAC81123.1| L1 cell adhesion molecule [Pan trogl... 148 1e-33
gi|13492012|gb|AAK28043.1| transmembrane receptor Roundabout3 [D... 148 1e-33
gi|4732113|gb|AAD28610.1| neural cell adhesion molecule L1 [Cerc... 148 1e-33
gi|33354081|dbj|BAC81124.1| L1 cell adhesion molecule [Pongo pyg... 148 1e-33
gi|28573310|ref|NP_788286.1| CG33141-PA [Drosophila melanogaster... 147 2e-33
gi|8572742|gb|AAF77184.1| SNS [Drosophila melanogaster] 147 2e-33
gi|2181948|emb|CAA33148.1| cell adhesion molecule (AA 1 - 681) (... 147 3e-33
gi|31323699|gb|AAP47136.1| sialoadhesin [Sus scrofa] 146 4e-33
gi|37547126|ref|XP_056455.3| Melanoma associated gene [Homo sapi... 146 4e-33
gi|15030115|gb|AAH11310.1| Ncam1 protein [Mus musculus] 146 4e-33
gi|18450276|ref|NP_035005.1| neural cell adhesion molecule 1 [Mu... 146 4e-33
gi|1504040|dbj|BAA13219.1| similar to D.melanogaster peroxidasin... 146 4e-33
gi|400402|sp|P13595|NCA1_MOUSE Neural cell adhesion molecule 1, ... 146 4e-33
gi|47220346|emb|CAF98445.1| unnamed protein product [Tetraodon n... 146 5e-33
gi|28373129|ref|NP_780775.1| contactin 5 isoform short; neural a... 145 7e-33
gi|400398|sp|P31836|NCA1_BOVIN Neural cell adhesion molecule 1, ... 145 7e-33
gi|27806019|ref|NP_776824.1| cell adhesion molecule, neural [Bos... 145 7e-33
gi|45642714|ref|NP_990790.1| smooth muscle myosin light chain ki... 145 7e-33
gi|7657359|ref|NP_055176.1| contactin 5 isoform long; neural adh... 145 7e-33
gi|14276867|gb|AAK58428.1| roundabout3 [Danio rerio] 145 9e-33
gi|86236|pir||S01998 contactin precursor - chicken >gnl|BL_ORD_I... 145 9e-33
gi|50728200|ref|XP_416029.1| PREDICTED: similar to neural cell r... 145 9e-33
gi|50754590|ref|XP_414434.1| PREDICTED: similar to cell adhesion... 145 9e-33
gi|45552153|ref|NP_995599.1| CG32019-PD [Drosophila melanogaster... 145 9e-33
gi|47224415|emb|CAG08665.1| unnamed protein product [Tetraodon n... 145 1e-32
gi|47227750|emb|CAG08913.1| unnamed protein product [Tetraodon n... 144 2e-32
gi|1439613|gb|AAB04558.1| neural cell adhesion molecule CD56; N-... 144 2e-32
gi|17536619|ref|NP_497045.1| basement membrane proteoglycan (2O9... 144 2e-32
gi|28574712|ref|NP_722954.2| CG31774-PA [Drosophila melanogaster... 144 2e-32
gi|40788219|dbj|BAA20801.2| KIAA0343 [Homo sapiens] 144 2e-32
gi|31236539|ref|XP_319431.1| ENSANGP00000002862 [Anopheles gambi... 144 2e-32
gi|72067|pir||IJRTNC neural cell adhesion molecule short domain ... 144 2e-32
gi|13928706|ref|NP_113709.1| neural cell adhesion molecule 1; ce... 144 2e-32
gi|41281937|ref|NP_851996.1| neural cell adhesion molecule 1; an... 144 2e-32
gi|33519481|ref|NP_004531.2| neural cell adhesion molecule 2 pre... 144 3e-32
gi|24647696|ref|NP_732242.1| CG31190-PA [Drosophila melanogaster... 144 3e-32
gi|459711|gb|AAB59959.1| neural cell adhesion molecule 143 4e-32
gi|2804782|gb|AAC38849.1| roundabout 1 [Drosophila melanogaster] 143 4e-32
gi|279680|pir||IJCHNL neural cell adhesion molecule long domain ... 143 4e-32
gi|2851523|sp|P13590|NCA1_CHICK Neural cell adhesion molecule 1,... 143 4e-32
gi|41054217|ref|NP_956098.1| contactin 5; wu:fi09g01 [Danio reri... 143 4e-32
gi|1708635|gb|AAC47451.1| neuroglian 143 4e-32
gi|459710|gb|AAB59957.1| neural cell adhesion molecule 143 4e-32
gi|35010|emb|CAA42508.1| Neural cell adhesion molecule L1 [Homo ... 143 5e-32
gi|50777737|ref|XP_427362.1| PREDICTED: similar to basement memb... 143 5e-32
gi|47227826|emb|CAG08989.1| unnamed protein product [Tetraodon n... 143 5e-32
gi|50758795|ref|XP_417421.1| PREDICTED: similar to mKIAA0230 pro... 142 8e-32
gi|11907988|gb|AAG41425.1| roundabout 2 [Drosophila melanogaster] 142 8e-32
gi|24580861|ref|NP_536792.2| CG5481-PA [Drosophila melanogaster]... 142 8e-32
gi|50729836|ref|XP_416673.1| PREDICTED: similar to roundabout ho... 142 1e-31
gi|39596592|emb|CAE63211.1| Hypothetical protein CBG07568 [Caeno... 142 1e-31
gi|31210307|ref|XP_314120.1| ENSANGP00000010312 [Anopheles gambi... 141 1e-31
gi|17136778|ref|NP_476899.1| CG13521-PA [Drosophila melanogaster... 141 1e-31
gi|39582691|emb|CAE65897.1| Hypothetical protein CBG11064 [Caeno... 141 1e-31
gi|45551150|ref|NP_726224.2| CG13521-PB [Drosophila melanogaster... 141 1e-31
gi|50738619|ref|XP_419328.1| PREDICTED: similar to kinase-like p... 141 2e-31
gi|20908094|tpg|DAA00021.1| TPA: TITIN [Drosophila melanogaster] 140 2e-31
gi|48097458|ref|XP_393788.1| similar to CG33141-PA [Apis mellifera] 140 2e-31
gi|45382937|ref|NP_989943.1| FAR-2 protein [Gallus gallus] >gnl|... 140 3e-31
gi|47219380|emb|CAG01543.1| unnamed protein product [Tetraodon n... 140 3e-31
gi|48102162|ref|XP_395296.1| similar to Neuroglian precursor [Ap... 140 3e-31
gi|34922043|sp|Q98902|CAML_FUGRU Neural cell adhesion molecule L... 140 3e-31
gi|3334268|sp|O15394|NCM2_HUMAN Neural cell adhesion molecule 2 ... 140 3e-31
gi|27894376|ref|NP_006605.2| cell adhesion molecule with homolog... 140 3e-31
gi|2190958|gb|AAB60937.1| neural cell adhesion molecule [Homo sa... 140 3e-31
gi|28573429|ref|NP_524702.3| CG7449-PA [Drosophila melanogaster]... 140 4e-31
gi|11079653|ref|NP_032504.2| L1 cell adhesion molecule [Mus musc... 140 4e-31
gi|211279|gb|AAA48632.1| cell adhesion molecule 140 4e-31
gi|226133|prf||1411301A neural adhesion mol L1 140 4e-31
gi|50728120|ref|XP_429293.1| PREDICTED: hypothetical protein XP_... 140 4e-31
gi|28573431|ref|NP_788355.1| CG7449-PB [Drosophila melanogaster]... 140 4e-31
gi|41281389|ref|NP_005001.2| neuronal cell adhesion molecule; Br... 139 5e-31
gi|47213522|emb|CAF96065.1| unnamed protein product [Tetraodon n... 139 5e-31
gi|6625978|gb|AAF19446.1| hibris [Drosophila melanogaster] 139 5e-31
gi|21758974|dbj|BAC05429.1| unnamed protein product [Homo sapiens] 139 5e-31
gi|345685|pir||A43425 Bravo/Nr-CAM cell adhesion molecule L1 hom... 139 7e-31
gi|47225700|emb|CAG08043.1| unnamed protein product [Tetraodon n... 139 9e-31
gi|462740|sp|P35331|NRCA_CHICK Neuronal cell adhesion molecule p... 139 9e-31
gi|45383994|ref|NP_990597.1| Nr-CAM protein [Gallus gallus] >gnl... 139 9e-31
gi|47228828|emb|CAG07560.1| unnamed protein product [Tetraodon n... 139 9e-31
gi|38372441|sp|Q810U4|NRCA_MOUSE Neuronal cell adhesion molecule... 138 1e-30
gi|29789453|ref|NP_795904.2| neuronal cell adhesion molecule [Mu... 138 1e-30
gi|31236138|ref|XP_319362.1| ENSANGP00000006165 [Anopheles gambi... 138 1e-30
gi|8134651|sp|Q91048|PTK7_CHICK Tyrosine-protein kinase-like 7 p... 138 1e-30
gi|48095518|ref|XP_394463.1| similar to CG12676-PA [Apis mellifera] 138 1e-30
gi|21391898|gb|AAM48303.1| AT03867p [Drosophila melanogaster] 138 1e-30
gi|7441747|pir||JE0100 neural cell adhesion molecule 2 - African... 137 2e-30
gi|24580839|ref|NP_608592.2| CG5423-PA [Drosophila melanogaster]... 137 2e-30
gi|11907990|gb|AAG41426.1| roundabout 3 [Drosophila melanogaster] 137 2e-30
gi|41137114|ref|XP_039627.9| contactin 3 (plasmacytoma associate... 137 2e-30
gi|16758746|ref|NP_446331.1| contactin 4; axonal-associated cell... 137 3e-30
gi|28972161|dbj|BAC65534.1| mKIAA0343 protein [Mus musculus] 137 3e-30
gi|6651057|gb|AAF22153.1| neural cell adhesion molecule L1 [Mus ... 137 3e-30
gi|48094384|ref|XP_394162.1| similar to MGC68806 protein [Apis m... 137 3e-30
gi|547997|sp|P36335|NCA2_XENLA Neural cell adhesion molecule 2, ... 136 4e-30
gi|34535186|dbj|BAC87234.1| unnamed protein product [Homo sapiens] 136 4e-30
gi|27370508|ref|NP_766592.1| contactin 4; axonal-associated cell... 136 4e-30
gi|26006253|dbj|BAC41469.1| mKIAA1132 protein [Mus musculus] 136 6e-30
gi|2511666|emb|CAA04507.1| NrCAM protein [Homo sapiens] 135 7e-30
gi|6651380|gb|AAF22282.1| NgCAM-related related cell adhesion mo... 135 7e-30
gi|6651381|gb|AAF22283.1| NgCAM-related related cell adhesion mo... 135 7e-30
gi|33112413|sp|Q92823|NRCA_HUMAN Neuronal cell adhesion molecule... 135 7e-30
gi|50760107|ref|XP_425794.1| PREDICTED: similar to transmembrane... 135 1e-29
gi|26333963|dbj|BAC30699.1| unnamed protein product [Mus musculus] 135 1e-29
gi|15425681|dbj|BAB64297.1| I-connectin [Procambarus clarkii] 135 1e-29
gi|18859063|ref|NP_571277.1| neural cell adhesion molecule 1; ce... 134 2e-29
gi|32822812|gb|AAH55053.1| C130076O07Rik protein [Mus musculus] 134 2e-29
gi|6680936|ref|NP_031723.1| cell adhesion molecule with homology... 134 2e-29
gi|28373122|ref|NP_783200.1| contactin 4 isoform a precursor; ax... 134 2e-29
gi|7441746|pir||JE0099 neural cell adhesion molecule 1 - African... 134 2e-29
gi|27652188|gb|AAO17583.1| L1 cell adhesion molecule [Homo sapie... 134 3e-29
gi|47213409|emb|CAF93208.1| unnamed protein product [Tetraodon n... 134 3e-29
gi|36143027|gb|AAQ85080.1| neural adhesion molecule L1.2 [Danio ... 134 3e-29
gi|21428708|gb|AAM50014.1| SD04592p [Drosophila melanogaster] 134 3e-29
gi|50729870|ref|XP_425540.1| PREDICTED: similar to neural cell a... 134 3e-29
gi|127855|sp|P16170|NCA1_XENLA Neural cell adhesion molecule 1, ... 134 3e-29
gi|42821116|ref|NP_981954.1| neural cell adhesion molecule 2; fa... 133 4e-29
gi|27652282|gb|AAO17630.1| L1 cell adhesion molecule [Pan troglo... 133 4e-29
gi|42528323|gb|AAS18426.1| fasciclin II GPI-linked protein isofo... 133 4e-29
gi|28558739|ref|NP_726608.2| CG32019-PA [Drosophila melanogaster... 133 4e-29
gi|6755584|ref|NP_035556.1| sialoadhesin [Mus musculus] >gnl|BL_... 133 4e-29
gi|50760226|ref|XP_425812.1| PREDICTED: similar to neural cell a... 133 4e-29
gi|21240773|gb|AAB52657.2| Sensory axon guidance protein 3, isof... 133 5e-29
gi|25147920|ref|NP_741748.1| sensory AXon guidance SAX-3, rounda... 133 5e-29
gi|19924211|ref|NP_446361.1| neurofascin [Rattus norvegicus] >gn... 132 6e-29
gi|20455467|sp|Q05695|CAML_RAT Neural cell adhesion molecule L1 ... 132 6e-29
gi|8393820|ref|NP_059041.1| neural cell adhesion molecule L1 [Ra... 132 6e-29
gi|7959253|dbj|BAA96020.1| KIAA1496 protein [Homo sapiens] 132 8e-29
gi|47224417|emb|CAG08667.1| unnamed protein product [Tetraodon n... 132 8e-29
gi|21752491|dbj|BAC04201.1| unnamed protein product [Homo sapiens] 132 8e-29
gi|1842427|gb|AAB47753.1| ankyrin binding cell adhesion molecule... 132 8e-29
gi|6679207|ref|NP_032805.1| contactin 3; plasmacytoma-associated... 132 8e-29
gi|6754920|ref|NP_035084.1| neural cell adhesion molecule 2; olf... 132 1e-28
gi|14276863|gb|AAK58426.1| roundabout1 [Danio rerio] 132 1e-28
gi|3334269|sp|O35136|NCM2_MOUSE Neural cell adhesion molecule 2 ... 132 1e-28
gi|38014810|gb|AAH60500.1| MGC68806 protein [Xenopus laevis] 132 1e-28
gi|30425042|ref|NP_780377.1| PTK7 protein tyrosine kinase 7 [Mus... 131 1e-28
gi|557250|emb|CAA85268.1| sialoadhesin [Mus musculus] 131 1e-28
gi|6919968|sp|Q62230|SN_MOUSE Sialoadhesin precursor (Sialic aci... 131 1e-28
gi|1842431|gb|AAB47755.1| ankyrin binding cell adhesion molecule... 131 2e-28
gi|49119255|gb|AAH73282.1| Unknown (protein for MGC:80658) [Xeno... 131 2e-28
gi|20143918|ref|NP_597676.1| titin isoform novex-1; connectin; C... 131 2e-28
gi|17066108|emb|CAD12459.1| Titin Novex-1 Isoform [Homo sapiens] 131 2e-28
gi|38372401|sp|P97686|NRCA_RAT Neuronal cell adhesion molecule p... 131 2e-28
gi|42655823|ref|XP_046808.11| neurofascin [Homo sapiens] 130 2e-28
gi|1842429|gb|AAB47754.1| ankyrin binding cell adhesion molecule... 130 2e-28
gi|38372284|sp|O94856|NFAS_HUMAN Neurofascin precursor 130 2e-28
gi|38372259|sp|P97685|NFAS_RAT Neurofascin precursor 130 2e-28
gi|39597744|emb|CAE68436.1| Hypothetical protein CBG14221 [Caeno... 130 2e-28
gi|20521151|dbj|BAA34476.2| KIAA0756 protein [Homo sapiens] 130 2e-28
gi|38372283|sp|O42414|NFAS_CHICK Neurofascin precursor >gnl|BL_O... 130 3e-28
gi|11277081|pir||T43027 neural cell adhesion molecule L1 - goldf... 130 3e-28
gi|283899|pir||S26180 neurofascin - chicken >gnl|BL_ORD_ID|14641... 130 3e-28
gi|50760291|ref|XP_417958.1| PREDICTED: similar to neurofascin [... 130 3e-28
gi|34535397|dbj|BAC87305.1| unnamed protein product [Homo sapiens] 130 3e-28
gi|38089779|ref|XP_146674.3| similar to immunoglobulin superfami... 130 4e-28
gi|29134779|dbj|BAC66140.1| projectin [Procambarus clarkii] 130 4e-28
gi|31201737|ref|XP_309816.1| ENSANGP00000018216 [Anopheles gambi... 129 5e-28
gi|37360078|dbj|BAC98017.1| mKIAA0756 protein [Mus musculus] 129 5e-28
gi|45383896|ref|NP_989436.1| sidekick 1 [Gallus gallus] >gnl|BL_... 129 5e-28
gi|47226301|emb|CAG09269.1| unnamed protein product [Tetraodon n... 129 5e-28
gi|18859065|ref|NP_571905.1| neural cell adhesion molecule 2 [Da... 129 7e-28
gi|21104338|emb|CAC85752.1| obscurin [Homo sapiens] 129 7e-28
gi|41222723|ref|XP_373319.1| similar to hemicentin [Homo sapiens] 129 7e-28
gi|50752572|ref|XP_422837.1| PREDICTED: similar to immunoglobuli... 129 7e-28
gi|35215309|ref|NP_874385.1| neurofascin [Mus musculus] >gnl|BL_... 129 9e-28
gi|47058952|ref|NP_037282.1| neuron-glia-CAM-related cell adhesi... 128 1e-27
gi|46369969|gb|AAS89820.1| neuronal cell adhesion molecule long ... 128 1e-27
gi|46369973|gb|AAS89822.1| neuronal cell adhesion molecule long ... 128 1e-27
gi|46369975|gb|AAS89823.1| neuronal cell adhesion molecule long ... 128 1e-27
gi|46369971|gb|AAS89821.1| neuronal cell adhesion molecule long ... 128 1e-27
gi|34865157|ref|XP_343057.1| neuron-glia-CAM-related cell adhesi... 128 1e-27
gi|46369977|gb|AAS89824.1| neuronal cell adhesion molecule long ... 128 1e-27
gi|37539895|ref|XP_351855.1| similar to cDNA sequence BC034076 [... 128 1e-27
gi|34867440|ref|XP_213677.2| roundabout (axon guidance receptor,... 128 2e-27
gi|27886609|ref|NP_690622.1| PTK7 protein tyrosine kinase 7 isof... 128 2e-27
gi|47938093|gb|AAH71557.1| PTK7 protein tyrosine kinase 7, isofo... 128 2e-27
gi|2136061|pir||JC4593 protein-tyrosine kinase-related receptor ... 128 2e-27
gi|15826840|ref|NP_002812.2| PTK7 protein tyrosine kinase 7 isof... 128 2e-27
gi|31199227|ref|XP_308561.1| ENSANGP00000009569 [Anopheles gambi... 128 2e-27
gi|20143914|ref|NP_003310.2| titin isoform N2-B; connectin; CMH9... 128 2e-27
gi|114735|sp|P28685|AXO1_CHICK Contactin 2 precursor (Axonin-1) ... 127 2e-27
gi|50760293|ref|XP_417959.1| PREDICTED: similar to axonin-1 [Gal... 127 2e-27
gi|31213065|ref|XP_315476.1| ENSANGP00000021235 [Anopheles gambi... 127 2e-27
gi|50511265|dbj|BAD32618.1| mKIAA3024 protein [Mus musculus] 127 3e-27
gi|18859067|ref|NP_571906.1| neural cell adhesion molecule 3 [Da... 127 3e-27
gi|48107961|ref|XP_396192.1| similar to roundabout 1 [Apis melli... 127 3e-27
gi|47223898|emb|CAG06075.1| unnamed protein product [Tetraodon n... 127 3e-27
gi|1621283|gb|AAC50765.1| hBRAVO/Nr-CAM precursor 127 3e-27
gi|34860609|ref|XP_235959.2| similar to immunoglobulin superfami... 127 3e-27
gi|17066104|emb|CAD12455.1| N2B-Titin Isoform [Homo sapiens] 127 3e-27
gi|6981246|ref|NP_037357.1| contactin 6; neural adhesion molecul... 126 4e-27
gi|47940323|gb|AAH72368.1| MGC84491 protein [Xenopus laevis] 126 4e-27
gi|49117906|gb|AAH72835.1| Unknown (protein for MGC:80200) [Xeno... 126 4e-27
gi|19852056|gb|AAL99983.1| Down syndrome cell adhesion molecule-... 126 4e-27
gi|20143922|ref|NP_597681.1| titin isoform novex-2; connectin; C... 126 6e-27
gi|39592554|emb|CAE63631.1| Hypothetical protein CBG08127 [Caeno... 125 8e-27
gi|11276093|ref|NP_062179.1| FMS-like tyrosine kinase 1; Fms-rel... 125 8e-27
gi|7657361|ref|NP_055276.1| contactin 6; neural adhesion molecul... 125 8e-27
gi|47216683|emb|CAG05180.1| unnamed protein product [Tetraodon n... 125 8e-27
gi|2136280|pir||I38344 titin, cardiac muscle [validated] - human 125 8e-27
gi|1212992|emb|CAA62188.1| titin [Homo sapiens] 125 8e-27
gi|47227360|emb|CAF96909.1| unnamed protein product [Tetraodon n... 125 1e-26
gi|32880201|ref|NP_689957.2| sidekick homolog 1 [Homo sapiens] >... 125 1e-26
gi|40254254|ref|NP_766388.2| sidekick 2 [Mus musculus] >gnl|BL_O... 124 2e-26
gi|47223830|emb|CAF98600.1| unnamed protein product [Tetraodon n... 124 2e-26
gi|6012063|emb|CAB57301.1| neural cell adhesion molecule L1 [Mus... 124 2e-26
gi|7209914|dbj|BAA92367.1| neural recognition molecule NB-3 [Mus... 124 2e-26
gi|31980846|ref|NP_059079.2| contactin 6; neural recognition mol... 124 2e-26
gi|26335725|dbj|BAC31563.1| unnamed protein product [Mus musculus] 124 2e-26
gi|4827022|ref|NP_005067.1| contactin 2 precursor; transiently-e... 124 3e-26
gi|444868|prf||1908253A TAG-1 protein (axonin 1) 124 3e-26
gi|34853550|ref|XP_342409.1| similar to D030068H01 protein [Ratt... 124 3e-26
gi|14041957|dbj|BAB55049.1| unnamed protein product [Homo sapiens] 123 4e-26
gi|6981632|ref|NP_037016.1| contactin 2; transient axonal glycop... 123 4e-26
gi|45549089|ref|NP_477290.4| CG5227-PC [Drosophila melanogaster]... 123 4e-26
gi|28571083|ref|NP_599142.3| CG5227-PD [Drosophila melanogaster]... 123 4e-26
gi|26342350|dbj|BAC34837.1| unnamed protein product [Mus musculus] 123 5e-26
gi|6691810|emb|CAB65848.1| EG:BACR19J1.1 [Drosophila melanogaster] 123 5e-26
gi|50729838|ref|XP_416674.1| PREDICTED: similar to roundabout ho... 122 6e-26
gi|462073|sp|P22648|FAS2_SCHAM Fasciclin II precursor (FAS II) >... 122 8e-26
gi|48138212|ref|XP_396867.1| similar to CG12676-PA [Apis mellifera] 122 8e-26
gi|28373119|ref|NP_778203.1| contactin 1 isoform 2 precursor; gl... 122 8e-26
gi|8134650|sp|Q13308|PTK7_HUMAN Tyrosine-protein kinase-like 7 p... 122 8e-26
gi|414791|emb|CAA79696.1| contactin [Homo sapiens] 122 8e-26
gi|28373117|ref|NP_001834.2| contactin 1 isoform 1 precursor; gl... 122 8e-26
gi|22477205|gb|AAH36569.1| CNTN1 protein [Homo sapiens] 122 1e-25
gi|31208805|ref|XP_313369.1| ENSANGP00000011303 [Anopheles gambi... 122 1e-25
gi|22902130|ref|NP_690621.1| PTK7 protein tyrosine kinase 7 isof... 122 1e-25
gi|31201555|ref|XP_309725.1| ENSANGP00000012618 [Anopheles gambi... 122 1e-25
gi|31982241|ref|NP_808317.2| cDNA sequence BC034076 [Mus musculu... 122 1e-25
gi|44890693|gb|AAH66864.1| Cntn1 protein [Mus musculus] 121 1e-25
gi|6680954|ref|NP_031753.1| contactin 1 [Mus musculus] >gnl|BL_O... 121 1e-25
gi|24581578|ref|NP_523469.2| CG12676-PA [Drosophila melanogaster... 121 1e-25
gi|12597263|gb|AAG60004.1| echinoid [Drosophila melanogaster] 121 1e-25
gi|47211487|emb|CAF95092.1| unnamed protein product [Tetraodon n... 120 2e-25
gi|26326581|dbj|BAC27034.1| unnamed protein product [Mus musculus] 120 2e-25
gi|41946117|gb|AAH66106.1| Cntn2 protein [Mus musculus] 120 2e-25
gi|47222083|emb|CAG12109.1| unnamed protein product [Tetraodon n... 120 2e-25
gi|15425683|dbj|BAB64298.1| Kettin [Procambarus clarkii] 120 3e-25
gi|31204473|ref|XP_311185.1| ENSANGP00000001527 [Anopheles gambi... 120 3e-25
gi|41281630|ref|NP_571458.1| neural adhesion molecule L1.1 [Dani... 120 4e-25
gi|31337510|emb|CAD66435.1| zormin [Drosophila melanogaster] 120 4e-25
gi|31204619|ref|XP_311258.1| ENSANGP00000001591 [Anopheles gambi... 120 4e-25
gi|1095168|prf||2107324A neural adhesion molecule F3 120 4e-25
gi|47228707|emb|CAG07439.1| unnamed protein product [Tetraodon n... 120 4e-25
gi|1430860|emb|CAA67504.1| brain-derived immunoglobulin superfam... 120 4e-25
gi|45580802|ref|NP_995962.1| CG33484-PA [Drosophila melanogaster... 120 4e-25
gi|48854852|ref|ZP_00309013.1| COG3210: Large exoproteins involv... 119 5e-25
gi|16923964|ref|NP_476459.1| contactin 1 [Rattus norvegicus] >gn... 119 5e-25
gi|21757394|dbj|BAC05109.1| unnamed protein product [Homo sapiens] 119 7e-25
gi|42659643|ref|XP_290502.2| KIAA1030 protein [Homo sapiens] 119 7e-25
gi|47211486|emb|CAF95091.1| unnamed protein product [Tetraodon n... 119 9e-25
gi|47223365|emb|CAG04226.1| unnamed protein product [Tetraodon n... 119 9e-25
gi|1363280|pir||A57112 contactin precursor - rat 119 9e-25
gi|50750381|ref|XP_421979.1| PREDICTED: similar to connectin/tit... 119 9e-25
gi|3219157|dbj|BAA28780.1| contactin A [Xenopus laevis] 118 1e-24
gi|47522704|ref|NP_999056.1| vascular cell adhesion molecule [Su... 118 2e-24
gi|30725824|ref|NP_851300.1| contactin 1 [Danio rerio] >gnl|BL_O... 117 2e-24
gi|1199461|gb|AAB59281.1| vascular cell adhesion molecule 117 3e-24
gi|6679036|ref|NP_032710.1| neogenin [Mus musculus] >gnl|BL_ORD_... 117 3e-24
gi|47209404|emb|CAF90870.1| unnamed protein product [Tetraodon n... 117 3e-24
gi|38614294|gb|AAH60237.1| Sdk1 protein [Mus musculus] 117 4e-24
gi|4507875|ref|NP_001069.1| vascular cell adhesion molecule 1 is... 116 5e-24
gi|15291623|gb|AAK93080.1| LD11008p [Drosophila melanogaster] 116 5e-24
gi|40714595|gb|AAR88555.1| LD10678p [Drosophila melanogaster] 116 5e-24
gi|45552151|ref|NP_995598.1| CG32019-PC [Drosophila melanogaster... 116 5e-24
gi|32451629|gb|AAH54540.1| Neo1 protein [Mus musculus] 116 6e-24
gi|4336724|gb|AAD17918.1| fasciclin II GPI-linked isoform [Mandu... 116 6e-24
gi|7511705|pir||T18531 tractin - medicinal leech >gnl|BL_ORD_ID|... 116 6e-24
gi|47221015|emb|CAF98244.1| unnamed protein product [Tetraodon n... 116 6e-24
gi|37537817|sp|Q90478|CAM1_BRARE Neural cell adhesion molecule L... 116 6e-24
gi|47086301|ref|NP_998033.1| hypothetical protein zgc:64208 [Dan... 116 6e-24
gi|4336726|gb|AAD17919.1| fasciclin II transmembrane isoform [Ma... 116 6e-24
gi|1843425|dbj|BAA13100.1| contactin/F3/F11 [Xenopus laevis] 115 1e-23
gi|50729608|ref|XP_416581.1| PREDICTED: similar to brother of CD... 114 2e-23
gi|27805871|ref|NP_776705.1| contactin 1 [Bos taurus] >gnl|BL_OR... 114 2e-23
gi|18252625|gb|AAL66362.1| brother of CDO [Danio rerio] 114 2e-23
gi|34863768|ref|XP_343403.1| neogenin [Rattus norvegicus] 114 2e-23
gi|40538872|ref|NP_954890.1| MAM domain containing glycosylphosp... 114 2e-23
gi|10720132|sp|P97603|NEO1_RAT Neogenin precursor >gnl|BL_ORD_ID... 114 2e-23
gi|28894262|gb|AAO52742.1| adhesion molecule VCAM-1 [Oryctolagus... 114 3e-23
gi|2078518|gb|AAC51287.1| neogenin [Homo sapiens] 114 3e-23
gi|46275816|ref|NP_996893.1| MAM domain containing 1; MAM domain... 114 3e-23
gi|15147240|ref|NP_150279.1| brother of CDO [Homo sapiens] >gnl|... 113 4e-23
gi|37181775|gb|AAQ88694.1| BOC [Homo sapiens] 113 4e-23
gi|47227363|emb|CAF96912.1| unnamed protein product [Tetraodon n... 113 5e-23
gi|30725726|ref|NP_849215.1| expressed sequence AW822216 [Mus mu... 113 5e-23
gi|4505375|ref|NP_002490.1| neogenin homolog 1; neogenin (chicke... 113 5e-23
gi|50754592|ref|XP_414435.1| PREDICTED: similar to Contactin 4, ... 113 5e-23
gi|37549383|ref|XP_051017.3| KIAA0657 protein [Homo sapiens] 112 7e-23
gi|21104330|emb|CAC85747.1| obscurin [Homo sapiens] 112 9e-23
gi|46403175|sp|Q7Z553|MDC1_HUMAN MAM domain containing protein 1... 112 9e-23
gi|48133425|ref|XP_393339.1| similar to EG:EG0007.3 [Apis mellif... 112 1e-22
gi|9651182|gb|AAF91086.1| nephrin [Rattus norvegicus] 112 1e-22
gi|37181356|gb|AAQ88492.1| MAM-domain protein [Homo sapiens] 112 1e-22
gi|12018318|ref|NP_072150.1| nephrin [Rattus norvegicus] >gnl|BL... 112 1e-22
gi|20177992|sp|Q9R044|NPHN_RAT Nephrin precursor (Renal glomerul... 112 1e-22
gi|6681139|ref|NP_031857.1| deleted in colorectal carcinoma [Mus... 112 1e-22
gi|2275262|gb|AAC47655.1| leechCAM [Hirudo medicinalis] 111 1e-22
gi|31231678|ref|XP_318566.1| ENSANGP00000019615 [Anopheles gambi... 110 3e-22
gi|29289929|gb|AAL92552.1| neogenin [Danio rerio] 110 3e-22
gi|22003417|gb|AAM88671.1| neogenin [Danio rerio] 110 3e-22
gi|6978755|ref|NP_036973.1| deleted in colorectal carcinoma; Del... 110 3e-22
gi|27545187|ref|NP_775325.1| neogenin 1 [Danio rerio] >gnl|BL_OR... 110 3e-22
gi|45645161|gb|AAS73243.1| neuronal cell adhesion molecule [Bos ... 110 3e-22
gi|2134173|pir||I51669 tumor suppressor - African clawed frog >g... 110 3e-22
gi|31236143|ref|XP_319363.1| ENSANGP00000006166 [Anopheles gambi... 110 4e-22
gi|14017951|dbj|BAB47496.1| KIAA1867 protein [Homo sapiens] 110 4e-22
gi|26006461|ref|NP_115920.1| kin of IRRE like 3 [Homo sapiens] >... 110 4e-22
gi|37182605|gb|AAQ89103.1| NEPH2 [Homo sapiens] 110 4e-22
gi|47222973|emb|CAF99129.1| unnamed protein product [Tetraodon n... 110 4e-22
gi|34855795|ref|XP_218523.2| similar to B lymphocyte cell adhesi... 110 4e-22
gi|19584322|emb|CAD28458.1| hypothetical protein [Homo sapiens] 109 6e-22
gi|34857640|ref|XP_346712.1| hypothetical protein XP_346711 [Rat... 109 6e-22
gi|9506949|ref|NP_062202.1| contactin 3; Plasmacytoma-associated... 109 6e-22
gi|34864224|ref|XP_236346.2| similar to putative neuronal cell a... 109 7e-22
gi|1480842|gb|AAB05806.1| cell adhesion molecule n-cam [Danio re... 109 7e-22
gi|38648725|gb|AAH63072.1| Kirrel3 protein [Mus musculus] 109 7e-22
gi|26337297|dbj|BAC32333.1| unnamed protein product [Mus musculus] 109 7e-22
gi|26329731|dbj|BAC28604.1| unnamed protein product [Mus musculu... 109 7e-22
gi|45383103|ref|NP_989869.1| sidekick 2 [Gallus gallus] >gnl|BL_... 109 7e-22
gi|29824425|ref|NP_080600.1| membrane protein mKirre; X kin of I... 109 7e-22
gi|47229254|emb|CAG04006.1| unnamed protein product [Tetraodon n... 108 1e-21
gi|6679571|ref|NP_033014.1| putative neuronal cell adhesion mole... 108 1e-21
gi|47213162|emb|CAG06233.1| unnamed protein product [Tetraodon n... 108 1e-21
gi|14669609|gb|AAK71998.1| brother of CDO [Xenopus laevis] 108 1e-21
gi|26341680|dbj|BAC34502.1| unnamed protein product [Mus musculu... 108 1e-21
gi|181493|gb|AAA35751.1| colorectal tumor suppressor (put.); put... 108 1e-21
gi|4885175|ref|NP_005206.1| deleted in colorectal carcinoma [Hom... 108 1e-21
gi|38090235|ref|XP_146640.3| similar to contactin 5 [Mus musculus] 108 1e-21
gi|24639637|ref|NP_726911.1| CG3665-PB [Drosophila melanogaster]... 108 1e-21
gi|4185887|emb|CAA21826.1| EG:EG0007.3 [Drosophila melanogaster] 108 1e-21
gi|17567577|ref|NP_508166.1| echinoid (XB466) [Caenorhabditis el... 108 1e-21
gi|24639639|ref|NP_726912.1| CG3665-PC [Drosophila melanogaster]... 108 1e-21
>gi|17568541|ref|NP_509635.1| high Incidence of Males due to increased
X chromosome loss HIM-4, hemicentin, cell adhesion and
meiotic chromosome segregation factor (570.8 kD) (him-4)
[Caenorhabditis elegans]
gi|11359751|pir||T43290 hemicentin precursor - Caenorhabditis elegans
gi|3328186|gb|AAC26792.1| hemicentin precursor [Caenorhabditis
elegans]
gi|3875956|emb|CAA87336.1| C. elegans HIM-4 protein (corresponding
sequence F15G9.4b) [Caenorhabditis elegans]
gi|3879658|emb|CAA87345.1| C. elegans HIM-4 protein (corresponding
sequence F15G9.4b) [Caenorhabditis elegans]
Length = 5198
Score = 3150 bits (8167), Expect = 0.0
Identities = 1547/1601 (96%), Positives = 1547/1601 (96%)
Frame = +2
Query: 2 ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH 181
ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH
Sbjct: 3598 ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH 3657
Query: 182 DFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDL 361
DFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDL
Sbjct: 3658 DFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDL 3717
Query: 362 TDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQP 541
TDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQP
Sbjct: 3718 TDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQP 3777
Query: 542 QVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWS 721
QVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWS
Sbjct: 3778 QVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWS 3837
Query: 722 CVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGS 901
CVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGS
Sbjct: 3838 CVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGS 3897
Query: 902 LIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDG 1081
LIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDG
Sbjct: 3898 LIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDG 3957
Query: 1082 IDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLS 1261
IDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLS
Sbjct: 3958 IDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLS 4017
Query: 1262 DKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVIEGELAVIECLVEGYPAPQVSW 1441
DKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVIEGELAVIECLVEGYPAPQVSW
Sbjct: 4018 DKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVIEGELAVIECLVEGYPAPQVSW 4077
Query: 1442 LRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPK 1621
LRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPK
Sbjct: 4078 LRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPK 4137
Query: 1622 IITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKA 1801
IITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKA
Sbjct: 4138 IITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKA 4197
Query: 1802 EERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCXXXXXXXX 1981
EERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKC
Sbjct: 4198 EERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCEIESESSE 4257
Query: 1982 XXXXKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVA 2161
KNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVA
Sbjct: 4258 FSWSKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVA 4317
Query: 2162 PKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATTKKKSVIFS 2341
PKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATTKKKSVIFS
Sbjct: 4318 PKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATTKKKSVIFS 4377
Query: 2342 SISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFLSCNATGIP 2521
SISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFLSCNATGIP
Sbjct: 4378 SISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFLSCNATGIP 4437
Query: 2522 EPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVN 2701
EPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVN
Sbjct: 4438 EPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVN 4497
Query: 2702 KPSDRPAPIWVECDEKGKPKKTEYMIDRGDTPDDNPQLLPWKDVEDSSLNGSIAYRCMPG 2881
KPSDRPAPIWVECDEKGKPKKTEYMIDRGDTPDDNPQLLPWKDVEDSSLNGSIAYRCMPG
Sbjct: 4498 KPSDRPAPIWVECDEKGKPKKTEYMIDRGDTPDDNPQLLPWKDVEDSSLNGSIAYRCMPG 4557
Query: 2882 PRSSRTVLLHAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEI 3061
PRSSRTVLLHAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEI
Sbjct: 4558 PRSSRTVLLHAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEI 4617
Query: 3062 AYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITCY 3241
AYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITCY
Sbjct: 4618 AYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITCY 4677
Query: 3242 ERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRH 3421
ERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRH
Sbjct: 4678 ERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRH 4737
Query: 3422 SIPHLTSAFEGVPEVKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIY 3601
SIPHLTSAFEGVPEVKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIY
Sbjct: 4738 SIPHLTSAFEGVPEVKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIY 4797
Query: 3602 XXXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNVYEGDFLPLTGFEGSGINIDDS 3781
EKYDEGVYKCVASNSIGKAFDDTQLNVYEGDFLPLTGFEGSGINIDDS
Sbjct: 4798 VLPNNSLVLLNVEKYDEGVYKCVASNSIGKAFDDTQLNVYEGDFLPLTGFEGSGINIDDS 4857
Query: 3782 SNAGGSSRREAYKKENEDASXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAKQYPTDDYH 3961
SNAGGSSRREAYKKENEDAS AKQYPTDDYH
Sbjct: 4858 SNAGGSSRREAYKKENEDASTTTITTTSPTTTTTETPLTTTIIPALITLPAKQYPTDDYH 4917
Query: 3962 EGSANDDGFGPTTQDSLFEFNPPLHPEISVVNTDCAGTINENGDCVDKDGKTHNLKILTG 4141
EGSANDDGFGPTTQDSLFEFNPPLHPEISVVNTDCAGTINENGDCVDKDGKTHNLKILTG
Sbjct: 4918 EGSANDDGFGPTTQDSLFEFNPPLHPEISVVNTDCAGTINENGDCVDKDGKTHNLKILTG 4977
Query: 4142 ENHCPEGFAMNPHTRICEDLDECAFYQPCDFECINYDGGFQCNCPLGYELAEEGCRDVNE 4321
ENHCPEGFAMNPHTRICEDLDECAFYQPCDFECINYDGGFQCNCPLGYELAEEGCRDVNE
Sbjct: 4978 ENHCPEGFAMNPHTRICEDLDECAFYQPCDFECINYDGGFQCNCPLGYELAEEGCRDVNE 5037
Query: 4322 CESVRCEDGKACFNQLGGYECIDDPCPANYSLVDDRYCEPECENCTSTPIQVHMLAIPSG 4501
CESVRCEDGKACFNQLGGYECIDDPCPANYSLVDDRYCEPECENCTSTPIQVHMLAIPSG
Sbjct: 5038 CESVRCEDGKACFNQLGGYECIDDPCPANYSLVDDRYCEPECENCTSTPIQVHMLAIPSG 5097
Query: 4502 LPISHIATLTAYDKSGRVLNDTTYAISDTGAPLARGRMTSGPFTIKAVKRGHAQVWTNRV 4681
LPISHIATLTAYDKSGRVLNDTTYAISDTGAPLARGRMTSGPFTIKAVKRGHAQVWTNRV
Sbjct: 5098 LPISHIATLTAYDKSGRVLNDTTYAISDTGAPLARGRMTSGPFTIKAVKRGHAQVWTNRV 5157
Query: 4682 LAAGDHHKVRVRAHSDHATNELHAPKETNFLVLINVGQYPF 4804
LAAGDHHKVRVRAHSDHATNELHAPKETNFLVLINVGQYPF
Sbjct: 5158 LAAGDHHKVRVRAHSDHATNELHAPKETNFLVLINVGQYPF 5198
Score = 411 bits (1057), Expect = e-113
Identities = 345/1302 (26%), Positives = 553/1302 (41%), Gaps = 63/1302 (4%)
Frame = +2
Query: 2 ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH 181
++G P P V W +NG +I Q N I N D+G+Y+C A+N G A
Sbjct: 3240 VTGRPVPYVTWKRNGKEIE---------QFNPVLHIRNATRADEGKYSCIASNEAGTAVA 3290
Query: 182 DFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDL 361
DF +DV + P F+ H T I EG++ + C I +SW K R +
Sbjct: 3291 DFLIDVFTKPTFETHETTFNIV-EGESAKIECKID-----GHPKPTISWLKGGRPFN--- 3341
Query: 362 TDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQP 541
DN+ +S G L I +A + GLYTC+A N G++ +FKV + + P ID D P
Sbjct: 3342 MDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYID-ETIDQTP 3400
Query: 542 QVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWS 721
+ I++C V G+P P++ W + V +D IV L+I ++ AG++S
Sbjct: 3401 KAVAGGEIILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNNYD-LKINSVTTEDAGQYS 3459
Query: 722 CVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKAL-GETITLFCNASGNPYPQLKWAKGG 898
C+A N+AG +V P K N + + +TIT+ C + P P + W +G
Sbjct: 3460 CIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPSISWFRGD 3519
Query: 899 SLIF------DSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVP 1060
++ SPDG+ I++ A+L +D G Y C+A N AGTS+ + + +LVP
Sbjct: 3520 KPVYLYDRYSISPDGSHITINKAKL-------SDGGKYICRASNEAGTSDIDLILKILVP 3572
Query: 1061 PEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQ 1240
P+I++ I +P +++ L+C G P P + WT NG + + + +A ++
Sbjct: 3573 PKIDKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFG 3632
Query: 1241 INNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVI--EGELAVIECLVE 1414
I NV ++D+G YTC A N G + +++DV+ P GT+ I EG+ + C ++
Sbjct: 3633 IENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIK 3692
Query: 1415 -----GYPAPQVSWLRNGNRVETGV-QGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAG 1576
VSW ++ ++ + V DGR LTI +A ++G+Y C A N AG
Sbjct: 3693 LAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDGRKLTISQASLENAGLYTCIALNRAG 3752
Query: 1577 SAQQAYTLEVLVSPKIITSTPGVLTP--SSGSKFSLPCAVRGYPDPIISWTLNGNDIKDG 1750
A + +E+L SP +I + + P + + CAV G+P P I W NG ++ D
Sbjct: 3753 EASLEFKVEIL-SPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDD 3811
Query: 1751 ENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYING 1927
EN + L I + + H + C A+NDAG LE + P +S + I
Sbjct: 3812 ENIRIVEQGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKA 3871
Query: 1928 SEGTETVIKCXXXXXXXXXXXXKNGVPLLPSNNLIF-SEDYKLIKILSTRL-------SD 2083
T T+ K G +LIF S D I + RL +D
Sbjct: 3872 LGETITLFCNASGNPYPQLKWAKGG-------SLIFDSPDGARISLKGARLDIPHLKKTD 3924
Query: 2084 QGEYSCTAANKAGNATQKTNLNVGVAPKIME-----RPRTQVVHKGDQVTLWCEASGVPQ 2248
G+Y+C A N AG + +++V V P+I PR + +TL C A G P
Sbjct: 3925 VGDYTCQALNAAGTSEASVSVDVLVPPEINRDGIDMSPR---LPAQQSLTLQCLAQGKPV 3981
Query: 2249 PAITWYKDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIV 2428
P + W + LT++ T + + +++S S GVYTC AEN VA ++ + +
Sbjct: 3982 PQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAEN-VAGSDNLMYNVD 4040
Query: 2429 MIPPEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSN---IAIQNNEKYQILGTT 2599
++ V+ + + C G P P +SW+R+ N +Q +Y G
Sbjct: 4041 VVQAPVISNGGTKQVIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQ-GVRYVTDGRM 4099
Query: 2600 LAIRNVLPDDDGFYHCIAKSDAG--------QKIATRKLIVNKPS----DRPAPIWVECD 2743
L I D G Y C A ++AG + + + K+I + P + + C
Sbjct: 4100 LTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCA 4159
Query: 2744 EKGKPKK-TEYMIDRGDTPDDNPQLLPWKDVE---DSSLNGSIAYRCMPGPRSSRTVLLH 2911
+G P + ++ D D D + + + Y C + L
Sbjct: 4160 VRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKAEERHLIYEC-TAKNDAGADTLE 4218
Query: 2912 AAPQFIVKPKNTTA-------AIGAIVELRCSAAGPPHPTITWAKDGKLIEDSK---FEI 3061
Q IV PK +T+ + G ++C +W+K+G + S F
Sbjct: 4219 FPVQTIVAPKISTSGNRYINGSEGTETVIKCEIES-ESSEFSWSKNGVPLLPSNNLIFSE 4277
Query: 3062 AYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVD--NNILPTPKPSSNQKNVAVIT 3235
Y +K+ SD GEY+C A N G++T +NV I+ P+ K V
Sbjct: 4278 DYKLIKILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTL 4337
Query: 3236 CYERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRR 3415
E + +TW Y + N G+ + SS+ +YTCK N
Sbjct: 4338 WCEASGVPQPAITW-YKDNELLTN-TGVDETATTKKKSVIFSSISPSQAGVYTCKAENWV 4395
Query: 3416 RHSIPHLTSAFEGVPE-VKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDD 3592
+ + PE V V N +V L C T P + W ++ + ++
Sbjct: 4396 ASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFLSCNATGIPEPV-ISWMRDSNIAIQNN 4454
Query: 3593 AIYXXXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNV 3718
Y D+G Y C+A + G+ +L V
Sbjct: 4455 EKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIV 4496
Score = 399 bits (1025), Expect = e-109
Identities = 343/1311 (26%), Positives = 548/1311 (41%), Gaps = 74/1311 (5%)
Frame = +2
Query: 8 GIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDF 187
G P P W N D+ + NN T + NV G Y C ATN+ G+A
Sbjct: 1941 GNPTPTAKWDFNQGDL---PKEAVFVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAVKTI 1997
Query: 188 SLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQV-MDVSWTKDSRALDGDLT 364
++ V + P F+ T+ + T+ LT I L D+ D + + +SWT + + + T
Sbjct: 1998 NVHVRTKPRFESGLTESEL-----TVNLTRSITLECDVDDAIGVGISWTVNGKPFLAE-T 2051
Query: 365 DNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQ 544
D V GR L I A ++ G Y C N AG A+ F + + PP I +
Sbjct: 2052 DGVQTLAGGRFLHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQVPPTIVNEGGEYT-- 2109
Query: 545 VAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSC 724
V N ++ C VTG P P + W K+G+ V D ++++++ +GQ +I+ + H G + C
Sbjct: 2110 VIENNSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEGQQFKIVHAEIAHKGSYIC 2169
Query: 725 VAENDAGVKELEMVLDVFTPPVVSVKSDNPIKAL-GETITLFC--NASGNPYPQLKWAKG 895
+A+ND G E+ +D+ T P++ N + A+ G + C + N Q+ W +
Sbjct: 2170 MAKNDVGTAEISFDVDIITRPMIQKGIKNIVTAIKGGALPFKCPIDDDKNFKGQIIWLRN 2229
Query: 896 GSLIFDSPDGARIS--LKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEI 1069
I + ARI+ RL I ++ + D G Y+C+ N AG + VLVPP I
Sbjct: 2230 YQPIDLEAEDARITRLSNDRRLTILNVTENDEGQYSCRVKNDAGENSFDFKATVLVPPTI 2289
Query: 1070 NRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVAS---DSTFIQ 1240
D + ++TL C A GKP P + W +G A+ + + + ++
Sbjct: 2290 IMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGELNGNQLK 2349
Query: 1241 INNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVIE---GELAVIECLV 1411
I + D G YTC A+N AGS NV+V+ P I G E E VI C V
Sbjct: 2350 ITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQNERVVISCPV 2409
Query: 1412 EGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQA 1591
P +++WL+ G +++ + V+ +G+ L + + R DS Y C ATNEAG+ ++
Sbjct: 2410 YARPPAKITWLKAGKPLQSD-KFVKTSANGQKLYLFKLRETDSSKYTCIATNEAGTDKRD 2468
Query: 1592 YTLEVLVSPKIITSTPGV---LTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGH 1762
+ + +LV+P P + +T +SG+ +L C +G P P I+W +GN I+ +
Sbjct: 2469 FKVSMLVAPSF--DEPNIVRRITVNSGNPSTLHCPAKGSPSPTITWLKDGNAIEPNDRYV 2526
Query: 1763 TIGADGTLHIEKAE-ERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGT 1939
A L I K E Y C A N G+D LE ++ I+ P I + EG
Sbjct: 2527 FFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIPPVIDGERREAVAVIEGF 2586
Query: 1940 ETVIKCXXXXXXXXXXXXKNGVPL----LPSNNLI-FSEDYKLIKILSTRLSDQGEYSCT 2104
+ + C K+G+ + L ++ I K + LS R SD G Y+C
Sbjct: 2587 SSELFCDSNSTGVDVEWQKDGLTINQDTLRGDSFIQIPSSGKKMSFLSARKSDSGRYTCI 2646
Query: 2105 AANKAGNATQKTNLNVGVAPKI---MERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDN 2275
N AG A + + V P I + Q + V + C SG P P + W D+
Sbjct: 2647 VRNPAGEARKLFDFAVNDPPSISDELSSANIQTIVPYYPVEINCVVSGSPHPKVYWLFDD 2706
Query: 2276 ELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPE 2455
+ L T +++ AG YTC+A+N V +D + V PP E
Sbjct: 2707 KPLEPDSAAYELTNNGETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLVRVTAPPHFEKE 2766
Query: 2456 RMNVSTNPRQTVFLSCNA-TGIPEPVISWMRDSNIAIQN---NEKYQILGTTLAIRNVLP 2623
R V T+ L+CNA + +P + W ++QN KY TL + N+
Sbjct: 2767 REEVVARVGDTMLLTCNAESSVPLSSVYWHAHDE-SVQNGVITSKYAANEKTLNVTNIQL 2825
Query: 2624 DDDGFYHCIAKSDAGQKIATRKLIVNK-----------PSDRPAPIWVECDEKGKPKKTE 2770
DD+GFY+C A ++AG KLIV + P + ++C G P T
Sbjct: 2826 DDEGFYYCTAVNEAGITKKFFKLIVIETPYFLDQQKLYPIILGKRLTLDCSATGTPPPTI 2885
Query: 2771 YMIDRGDTPDDNPQL----------LPWKDVEDSSLNGSIAYRCMPGPRSSRT-----VL 2905
+ G +++ ++ P K+VE Y C+ ++ R+ V
Sbjct: 2886 LFMKDGKRLNESDEVDIIGSTLVIDNPQKEVEG-------RYTCIAENKAGRSEKDMMVE 2938
Query: 2906 LHAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWA----KDGKLIEDSKFEIAYSH 3073
+ P+ + N G + L C ITW+ KDG+L ++ S
Sbjct: 2939 VLLPPKLSKEWINVEVQAGDPLTLECPIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSK 2998
Query: 3074 LKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPK---PSSNQKNVAVITCYE 3244
L + + D+ Y+C+A N G + + V+ PK S + + T E
Sbjct: 2999 LYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNT----PPKIFGDSFSTTEIVADTTLE 3054
Query: 3245 RNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLEL------------ 3388
+ G+P P+ F++ ++ + + K+GDL L
Sbjct: 3055 --------IPCRTEGIPPPEI---SWFLDGKPILEMPGVTYKQGDLSLRIDNIKPNQEGR 3103
Query: 3389 YTCKVRNRRRHSIPHLTSAFEGVPEVKTIDKV-EVNNGDSVVLDCEVTSDPLTTHVVWTK 3565
YTC N+ + P V +V V G + CEV +P V W K
Sbjct: 3104 YTCVAENKAGRAEQDTYVEISEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPV-VNWLK 3162
Query: 3566 NDQKMLDDDAIYXXXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNV 3718
+ + D + D G Y C+A+N G++ T + V
Sbjct: 3163 DGEPYTSDLLQFSTKLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEV 3213
Score = 392 bits (1008), Expect = e-107
Identities = 324/1309 (24%), Positives = 559/1309 (41%), Gaps = 61/1309 (4%)
Frame = +2
Query: 2 ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH 181
++G P P V WTK+G + S +L++ + F I + ++ +G Y C A N G A
Sbjct: 2122 VTGKPNPVVTWTKDGRPVGDLKSVQVLSEGQQ-FKIVHAEIAHKGSYICMAKNDVGTAEI 2180
Query: 182 DFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDL 361
F +D+++ P +G + CPI ++ Q++ W ++ + +D +
Sbjct: 2181 SFDVDIITRPMIQKGIKNIVTAIKGGALPFKCPIDDDKNFKGQII---WLRNYQPIDLEA 2237
Query: 362 TD-NVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQ 538
D + + R+LTI + + G Y+C N AGE S +FK +L PP I + D
Sbjct: 2238 EDARITRLSNDRRLTILNVTENDEGQYSCRVKNDAGENSFDFKATVLVPPTIIMLDKDKN 2297
Query: 539 PQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQV----LQILRTDSDH 706
+ + C TG P P I W K+G+ + + I+ G++ L+I R
Sbjct: 2298 KTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGELNGNQLKITRIKEGD 2357
Query: 707 AGKWSCVAENDAGVKELEMVLDVFTPPVV---SVKSDNPIKALGETITLFCNASGNPYPQ 877
AGK++C A+N AG E ++ ++V T P + + SD + E + + C P +
Sbjct: 2358 AGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQ-NERVVISCPVYARPPAK 2416
Query: 878 LKWAKGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLV 1057
+ W K G + S + S G +L + L++TD YTC A N AGT + V +LV
Sbjct: 2417 ITWLKAGKPL-QSDKFVKTSANGQKLYLFKLRETDSSKYTCIATNEAGTDKRDFKVSMLV 2475
Query: 1058 PPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFI 1237
P + I + + TL C A+G P P + W +G A+ + + + +
Sbjct: 2476 APSFDEPNIVRRITVNSGNPSTLHCPAKGSPSPTITWLKDGNAIEPNDRYVFFDAGRQ-L 2534
Query: 1238 QINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTK--QVIEGELAVIECLV 1411
QI+ SD+G YTC A N GSD+L ++V+ PVI + VIEG + + C
Sbjct: 2535 QISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIPPVIDGERREAVAVIEGFSSELFC-D 2593
Query: 1412 EGYPAPQVSWLRNGNRVE----TGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGS 1579
V W ++G + G ++ + G+ ++ + AR DSG Y C N AG
Sbjct: 2594 SNSTGVDVEWQKDGLTINQDTLRGDSFIQIPSSGKKMSFLSARKSDSGRYTCIVRNPAGE 2653
Query: 1580 AQQAYTLEVLVSPKII--TSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGE 1753
A++ + V P I S+ + T + C V G P P + W + ++
Sbjct: 2654 ARKLFDFAVNDPPSISDELSSANIQTIVPYYPVEINCVVSGSPHPKVYWLFDDKPLEPDS 2713
Query: 1754 NGHTIGADG-TLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYING 1927
+ + +G TL I +++ H Y C A+N+ G +F V+ + AP +
Sbjct: 2714 AAYELTNNGETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLVR-VTAPPHFEKEREEVVA 2772
Query: 1928 SEGTETVIKCXXXXXXXXXXXXKNGVPLLPSNNLI---FSEDYKLIKILSTRLSDQGEYS 2098
G ++ C + N +I ++ + K + + + +L D+G Y
Sbjct: 2773 RVGDTMLLTCNAESSVPLSSVYWHAHDESVQNGVITSKYAANEKTLNVTNIQLDDEGFYY 2832
Query: 2099 CTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNE 2278
CTA N+AG + L V P +++ + + G ++TL C A+G P P I + KD +
Sbjct: 2833 CTAVNEAGITKKFFKLIVIETPYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGK 2892
Query: 2279 LLTNTG-VDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPE 2455
L + VD +T ++ + G YTC AEN +E+D+ + V++PP++ E
Sbjct: 2893 RLNESDEVDIIGST----LVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKE 2948
Query: 2456 RMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILG--TTLAIRNVLPDD 2629
+NV + L C I+W R Q + + Q + L I P+D
Sbjct: 2949 WINVEVQAGDPLTLECPIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSKLYIMQATPED 3008
Query: 2630 DGFYHCIAKSDAGQKIATRKLIVNKPSD------------RPAPIWVECDEKG-KPKKTE 2770
Y CIA +DAG A ++ VN P + + C +G P +
Sbjct: 3009 ADSYSCIAVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEIS 3068
Query: 2771 YMIDRGDTPDDNPQLLPWKD------VEDSSLNGSIAYRCMPGPRSSRT-----VLLHAA 2917
+ +D P + +K +++ N Y C+ ++ R V +
Sbjct: 3069 WFLD--GKPILEMPGVTYKQGDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEISEP 3126
Query: 2918 PQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGK-----LIEDSKFEIAYSHLKV 3082
P+ ++ + G +RC G P P + W KDG+ L++ S +++Y HL+
Sbjct: 3127 PRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKDGEPYTSDLLQFST-KLSYLHLRE 3185
Query: 3083 TLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQK-------NVAVITCY 3241
T + +D G YTC+A N G S + D +L P+ ++ N ++ C
Sbjct: 3186 T--TLADGGTYTCIATNKAGESQTT----TDVEVLVPPRIEDEERVLQGKEGNTYMVHCQ 3239
Query: 3242 ERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRH 3421
+ +TW+ NG + + +H N D Y+C N
Sbjct: 3240 VTGRPVPY-VTWKRNGKEIEQFNPVLHIRN-----------ATRADEGKYSCIASNEAGT 3287
Query: 3422 SIPHLTSAFEGVPEVKTIDKV-EVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAI 3598
++ P +T + + G+S ++C++ P T + W K + D+ I
Sbjct: 3288 AVADFLIDVFTKPTFETHETTFNIVEGESAKIECKIDGHPKPT-ISWLKGGRPFNMDNII 3346
Query: 3599 YXXXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNVYEGDFLPLT 3745
+++D G+Y CVA+NS G + D ++NVY ++ T
Sbjct: 3347 LSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDET 3395
Score = 367 bits (943), Expect = 1e-99
Identities = 331/1299 (25%), Positives = 545/1299 (41%), Gaps = 60/1299 (4%)
Frame = +2
Query: 2 ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH 181
+SG P P V W + + + L N ET I QV G YTC A N GKA
Sbjct: 2692 VSGSPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIVRSQVEHAGTYTCEAQNNVGKARK 2751
Query: 182 DFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSW-TKDSRALDGD 358
DF + V +PP F+ + + R GDT+ LTC + + ++ V W D +G
Sbjct: 2752 DFLVRVTAPPHFE-KEREEVVARVGDTMLLTCNAESSVPLS----SVYWHAHDESVQNGV 2806
Query: 359 LTDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQ 538
+T ++ + L ++ L++ G Y C A+N AG FK+ ++ P + + +
Sbjct: 2807 ITSKYAANE--KTLNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIETPYF-LDQQKLY 2863
Query: 539 PQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKW 718
P + + + + C+ TG P P+I ++K+GK + + + + I+ G L I + G++
Sbjct: 2864 P-IILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDII--GSTLVIDNPQKEVEGRY 2920
Query: 719 SCVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGG 898
+C+AEN AG E +M+++V PP +S + N G+ +TL C + W++
Sbjct: 2921 TCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLECPIEDTSGVHITWSRQF 2980
Query: 899 SLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRD 1078
A+ S ++L I D Y+C A+N AG +EA V V PP+I D
Sbjct: 2981 GKDGQLDMRAQSSSDKSKLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNTPPKIFGD 3040
Query: 1079 GIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSL 1258
+ + A +L + C +G P P++ W L+G + PG+T ++I+N+
Sbjct: 3041 SFS-TTEIVADTTLEIPCRTEGIPPPEISWFLDGKPIL-EMPGVTYKQGDLSLRIDNIKP 3098
Query: 1259 SDKGVYTCYAENVAGSDNLMYNVDVVQAP-VISNGGTKQVIEGELAVIECLVEGYPAPQV 1435
+ +G YTC AEN AG V++ + P V+ +V+EG I C V G P P V
Sbjct: 3099 NQEGRYTCVAENKAGRAEQDTYVEISEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVV 3158
Query: 1436 SWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVS 1615
+WL++G + + +++ T L + E D G Y C ATN+AG +Q +EVLV
Sbjct: 3159 NWLKDGEPYTSDL--LQFSTKLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEVLVP 3216
Query: 1616 PKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIE 1795
P+ I VL G+ + + C V G P P ++W NG +I+ + LHI
Sbjct: 3217 PR-IEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEIEQ--------FNPVLHIR 3267
Query: 1796 KAEER-HLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCXXXXX 1972
A Y C A N+AG +F + P T + N EG I+C
Sbjct: 3268 NATRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTF-NIVEGESAKIECKIDGH 3326
Query: 1973 XXXXXXXKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQKTNLNV 2152
G +N+I S + IL + D G Y+C A N G++ Q +NV
Sbjct: 3327 PKPTISWLKGGRPFNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNV 3386
Query: 2153 GVAPKIMER-PRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATTKKKS 2329
P I E +T G ++ L C G P P +TW + ++ + N
Sbjct: 3387 YTKPYIDETIDQTPKAVAGGEIILKCPVLGNPTPTVTWKRGDDAVPND--SRHTIVNNYD 3444
Query: 2330 VIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNV-STNPRQTVFLSCN 2506
+ +S++ AG Y+C A N + V+ P V + N+ T+ + C
Sbjct: 3445 LKINSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCG 3504
Query: 2507 ATGIPEPVISWMR-DSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAG----- 2668
T P P ISW R D + + + G+ + I D G Y C A ++AG
Sbjct: 3505 VTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAKLSDGGKYICRASNEAGTSDID 3564
Query: 2669 --------QKIATRKLIVNKPSDRPAPIWVECDEKGKPK------KTEYMIDRGDTPDDN 2806
KI +I N + I++EC G P+ K I+ D+
Sbjct: 3565 LILKILVPPKIDKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDSRVIL 3624
Query: 2807 PQLLPWKDVEDSSLNGSIAYRCMPGPRSSR-----TVLLHAAPQF-------IVKPKNTT 2950
Q +E+ + Y C R + ++ + + P+F +K + T
Sbjct: 3625 AQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDT 3684
Query: 2951 AAIGAIVELRCSAAGPPHPTITWAKDGKLIE---DSKFEIAYSHLKVTLNSTS--DSGEY 3115
+ ++L A ++W KD + ++ +I+ K+T++ S ++G Y
Sbjct: 3685 ITLTCPIKLAEDIADQV-MDVSWTKDSRALDGDLTDNVDISDDGRKLTISQASLENAGLY 3743
Query: 3116 TCMAQNSVGSSTVS--------AFINVDNNILPTPKPSSNQKNVAVITCYERNQAYSRGL 3271
TC+A N G +++ I++ N + P+ + NQ ++ C + +
Sbjct: 3744 TCIALNRAGEASLEFKVEILSPPVIDISRNDV-QPQVAVNQP--TIMRCAVTGHPFP-SI 3799
Query: 3272 TWEYNGVPMPKNLAGIHFMNNGS-LVILDTSSLKEGDLELYTCKVRNRRRHSIPHLTSAF 3448
W NG + + I + G L IL T S G ++C N
Sbjct: 3800 KWLKNGKEVTDD-ENIRIVEQGQVLQILRTDSDHAGK---WSCVAENDAG------VKEL 3849
Query: 3449 EGVPEVKTIDKVEVNN-------GDSVVLDCEVTSDPLTTHVVWTKNDQKMLD--DDAIY 3601
E V +V T V V + G+++ L C + +P + W K + D D A
Sbjct: 3850 EMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPY-PQLKWAKGGSLIFDSPDGARI 3908
Query: 3602 XXXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNV 3718
+K D G Y C A N+ G + ++V
Sbjct: 3909 SLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDV 3947
Score = 362 bits (928), Expect = 6e-98
Identities = 330/1318 (25%), Positives = 547/1318 (41%), Gaps = 79/1318 (5%)
Frame = +2
Query: 2 ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH 181
I G P P + W KNG D+ D + + N I + D G Y+C N GK
Sbjct: 726 IRGKPHPKIRWFKNGKDLIKPDDYIKI--NEGQLHIMGAKDEDAGAYSCVGENMAGKDVQ 783
Query: 182 DFSLDVLSPPEF--DIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDG 355
+L V P H + I+R+ +TL C LA I ++ W K + L
Sbjct: 784 VANLSVGRVPTIIESPHTVRVNIERQ---VTLQC---LAVGIPPP--EIEWQKGNVLLAT 835
Query: 356 DLTDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDV 535
DG L I+ A +E+ G +TCIA N G+ S + + +
Sbjct: 836 LNNPRYTQLADG-NLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVSPVLGHVPP 894
Query: 536 QPQVAVNQPTIMRCAVT-GHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAG 712
+ Q+ Q + C V G P PSI W+K+ K V + I+I G +L++ + G
Sbjct: 895 EEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEG 954
Query: 713 KWSCVAENDAG----------VKELEMVLD-----VFTPPV-------VSVKSDNPIKAL 826
K++C+A + AG +K+ E V VF P + V+V +
Sbjct: 955 KYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLD 1014
Query: 827 GETITLFCNASGNPYPQLKWAKGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQA 1006
GE + C SG P P + W G I + ++ L + K+ G YTCQA
Sbjct: 1015 GEGFAIPCVVSGTPPPIITWYLDGRPITPNSRDFTVTADNT-LIVRKADKSYSGVYTCQA 1073
Query: 1007 LNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTA 1186
N+AG +E ++ ++ P I+ S + T+ C G P P + W L+
Sbjct: 1074 TNSAGDNEQKTTIRIMNTPMISPG--QSSFNMVVDDLFTIPCDVYGDPKPVITWLLDDKP 1131
Query: 1187 LTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGT 1366
T V ++ + I NV+ + +G +TC+A+N AG+D + V P I+
Sbjct: 1132 FTEG-----VVNEDGSLTIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAENQ 1186
Query: 1367 KQV-IEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSG 1543
+++ ++ + V+EC + P P W G ++++ + DG L + + ++G
Sbjct: 1187 EKIALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDG-ALVLQNVKLENTG 1245
Query: 1544 IYLCSATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWT 1723
+++C +N AG +YTL V PKII+ PGV+ G +PC G P+ I +W
Sbjct: 1246 VFVCQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWN 1305
Query: 1724 LNGNDIKDGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKIS 1900
NG D+K E ++ GTL I +A++ + Y C N+AG + V P I
Sbjct: 1306 KNGIDLKMDEKKFSVDNLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHVDVQEPPIIL 1365
Query: 1901 TSGNRYINGSEGTETVIKCXXXXX-XXXXXXXKNGVPLLPSNNLIFSEDYKLIKILSTRL 2077
S G +KC + G+ + E + I S +
Sbjct: 1366 PSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRGIAIGTDTKGYVVESDGTLVIQSASV 1425
Query: 2078 SDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERP--RTQVVHKGDQVTLWCEASGVPQP 2251
D Y+C A+N AG A + V +P I + + + + +L+C P P
Sbjct: 1426 EDATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLP 1485
Query: 2252 AITWY-KDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIV 2428
I+WY D L+ + +T+ K+K +F + + +GVY C A N + + V
Sbjct: 1486 QISWYLNDKPLIDDKTSWKTSDDKRKLHVFKA-KITDSGVYKCVARNAAGEGSKSFQVEV 1544
Query: 2429 MIPPEVVPE--RMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQIL---- 2590
++P + + V + V L C +G P P I+W+ D + ++ +KY+
Sbjct: 1545 IVPLNLDESKYKKKVFAKEGEEVTLGCPVSGFPVPQINWVVDGTV-VEPGKKYKGATLSN 1603
Query: 2591 -GTTLAIRNVLPDDDGFYHCIAKSDA---------------------------GQKIATR 2686
G TL +V +G YHC+A+S G+ I+
Sbjct: 1604 DGLTLHFDSVSVKQEGNYHCVAQSKGNILDIDVELSVLAVPIVGEDDNLEVFLGKDISLS 1663
Query: 2687 KLIVNKPSDRPAPIW-VECDEKGKPKKTEYMIDRGDTPDDNPQLLPWKDVEDSSLNGSIA 2863
+ + D+ +W + E +P D P D +L + D+ +
Sbjct: 1664 CDLQTESDDKTTFVWSINGSESDRP-------DNVQIPSDGHRLY----ITDAKPENNGK 1712
Query: 2864 YRCM---PGPRSSRTVLLHA-APQFIVKP---KNTTAAIGAIVELRCSAAGPPHPTITWA 3022
Y C ++ RT+ L P V+P N + L+C G P PT+ W
Sbjct: 1713 YMCRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWK 1772
Query: 3023 KDGKLIEDS-KFEIAYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPK 3199
DG ++ S F+ + S L++ T S + +C A+N G+++ FI N PT K
Sbjct: 1773 IDGNDVDKSWLFDESLSLLRIE-KLTGKSAQISCTAENKAGTASRDFFI--QNIAAPTFK 1829
Query: 3200 PSSNQKNV----AVITCYERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSL 3367
+Q+ + IT +TW G+P+ +N A I ++N L IL+ +
Sbjct: 1830 NEGDQETIFRESETITLDCPVSLGDFQITWMKQGLPLTENDA-IFTLDNTRLTILNANRD 1888
Query: 3368 KEGDLELYTCKVRNRRRHSIPHLTSAFEGVPEVK-TIDKVEVNNGDSVVLDCEVTSDPLT 3544
E ++YTC N + +P++K + +E+N G+ ++L C+ +P
Sbjct: 1889 HE---DIYTCVANNTAGQVSKDFDVVVQVLPKIKNAVVTLEINEGEEIILTCDAEGNPTP 1945
Query: 3545 THVVWTKNDQKMLDDDAIYXXXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNV 3718
T W N Q L +A++ KY GVYKC A+N +G+A ++V
Sbjct: 1946 T-AKWDFN-QGDLPKEAVFVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAVKTINVHV 2001
Score = 354 bits (909), Expect = 1e-95
Identities = 319/1287 (24%), Positives = 526/1287 (40%), Gaps = 58/1287 (4%)
Frame = +2
Query: 8 GIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDF 187
G P P + W K+G I D R + I + +DQGRYTC ATN G +
Sbjct: 2504 GSPSPTITWLKDGNAIEPND-RYVFFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLEN 2562
Query: 188 SLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTD 367
+L+V+ PP D + EG + L C D +DV W KD ++ D
Sbjct: 2563 TLEVIIPPVIDGERREAVAVIEGFSSELFC------DSNSTGVDVEWQKDGLTINQDTLR 2616
Query: 368 N---VDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQ 538
+ I G+K++ A ++G YTCI N AGEA F + PP I +
Sbjct: 2617 GDSFIQIPSSGKKMSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVNDPPSISDELSSAN 2676
Query: 539 PQVAVNQ-PTIMRCAVTGHPFPSIKWLKNGKEVTDDENI-RIVEQGQVLQILRTDSDHAG 712
Q V P + C V+G P P + WL + K + D + G+ L+I+R+ +HAG
Sbjct: 2677 IQTIVPYYPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIVRSQVEHAG 2736
Query: 713 KWSCVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGN-PYPQLKWA 889
++C A+N+ G + ++ V PP + + + +G+T+ L CNA + P + W
Sbjct: 2737 TYTCEAQNNVGKARKDFLVRVTAPPHFEKEREEVVARVGDTMLLTCNAESSVPLSSVYWH 2796
Query: 890 KGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEI 1069
+ + ++ + L++ +++ D G Y C A+N AG ++ + V+ P
Sbjct: 2797 AHDESVQNGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIETPYF 2856
Query: 1070 NRDGIDMSPRLPA--QQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQI 1243
+D P + LTL C A G P P + + +G L S + S + I
Sbjct: 2857 ----LDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDIIGST---LVI 2909
Query: 1244 NNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTK-QVIEGELAVIECLVEGY 1420
+N +G YTC AEN AG V+V+ P +S +V G+ +EC +E
Sbjct: 2910 DNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLECPIEDT 2969
Query: 1421 PAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTL 1600
++W R + + +D L I++A D+ Y C A N+AG A+ + +
Sbjct: 2970 SGVHITWSRQFGKDGQLDMRAQSSSDKSKLYIMQATPEDADSYSCIAVNDAGGAEAVFQV 3029
Query: 1601 EVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADG 1780
V PKI + + + +PC G P P ISW L+G I + D
Sbjct: 3030 TVNTPPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFLDGKPILEMPGVTYKQGDL 3089
Query: 1781 TLHIEKAE-ERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKC 1957
+L I+ + + Y C A+N AG + V+ P++ + + EG +T I+C
Sbjct: 3090 SLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEISEPPRV-VMASEVMRVVEGRQTTIRC 3148
Query: 1958 XXXXXXXXXXX-XKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQ 2134
K+G P S+ L FS + + T L+D G Y+C A NKAG +
Sbjct: 3149 EVFGNPEPVVNWLKDGEPYT-SDLLQFSTKLSYLHLRETTLADGGTYTCIATNKAGESQT 3207
Query: 2135 KTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETAT 2314
T++ V V P+I + R +G+ + C+ +G P P +TW ++ + +
Sbjct: 3208 TTDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEIEQF------- 3260
Query: 2315 TKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVF 2494
+ + + + G Y+C A N + D + V P + ++
Sbjct: 3261 --NPVLHIRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNIVEGESAK 3318
Query: 2495 LSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQ- 2671
+ C G P+P ISW++ +N G TL I D G Y C+A + G
Sbjct: 3319 IECKIDGHPKPTISWLKGGRPFNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDS 3378
Query: 2672 ------KIATRKLIVNKPSDRP-----APIWVECDEKGKPKKTEYMIDRGD--TPDDNPQ 2812
+ T+ I P I ++C G P T RGD P+D+
Sbjct: 3379 EQDFKVNVYTKPYIDETIDQTPKAVAGGEIILKCPVLGNPTPT-VTWKRGDDAVPNDSRH 3437
Query: 2813 -LLPWKDVEDSSLNGSIA--YRCMPGPRSSRTVLLHAA-----PQFIVKPKNTTAAI-GA 2965
++ D++ +S+ A Y C+ + +AA P F+ K N I
Sbjct: 3438 TIVNNYDLKINSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIEND 3497
Query: 2966 IVELRCSAAGPPHPTITWAKDGK---LIEDSKFEIAYSHLKVTLNSTSDSGEYTCMAQNS 3136
+ + C P P+I+W + K L + SH+ + SD G+Y C A N
Sbjct: 3498 TITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAKLSDGGKYICRASNE 3557
Query: 3137 VGSSTVSAFINVDNNILPTPKPSSN--QKNVAVITCYERNQAYSRGLTWEYNGVPMPKNL 3310
G+S + + + ++P SN +A++ A + L +G+P P +
Sbjct: 3558 AGTSDIDLILKI---LVPPKIDKSNIIGNPLAIV-------ARTIYLECPISGIPQPDVI 3607
Query: 3311 ---AGIHFMNNGSLVILDTSSLKEG-------DLELYTCKVRNRRRHSIPHLTSAFEGVP 3460
G+ S VIL ++ G D YTC NR + + P
Sbjct: 3608 WTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPP 3667
Query: 3461 E--VKTIDKVEVNNGDSVVLDCEV-TSDPLTTHVV---WTKNDQKM---LDDDAIYXXXX 3613
E + GD++ L C + ++ + V+ WTK+ + + L D+
Sbjct: 3668 EFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDG 3727
Query: 3614 XXXXXXXXEKYDEGVYKCVASNSIGKA 3694
+ G+Y C+A N G+A
Sbjct: 3728 RKLTISQASLENAGLYTCIALNRAGEA 3754
Score = 319 bits (817), Expect = 5e-85
Identities = 314/1317 (23%), Positives = 536/1317 (39%), Gaps = 84/1317 (6%)
Frame = +2
Query: 26 VIWTKNGMDINMTDSRVILAQNNET--FGIENVQVTDQGRYTCTATNRGGKASHDFSLDV 199
+ W K G DI + N +T + I + + D G Y C + G S ++
Sbjct: 460 IYWVKTGEDII---GGPLFYHNTDTSVWTIPELSLKDAGEYECRVISNNGNYSVKTRVET 516
Query: 200 L-SPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVD 376
SPPE I G + G+ L C + A ++ ++ WT+ + N +
Sbjct: 517 RESPPE--IFGVRNVSVPLGEAAFLHCSTRSAGEV-----EIRWTRYGATVFNG--PNTE 567
Query: 377 ISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVN 556
+ L I + +AG+Y C+A N G ++ + +++I+ PP + ++ DV +
Sbjct: 568 RNPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMRLDIMEPPSVKVTPQDVY--FNMR 625
Query: 557 QPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSCVAEN 736
+ + C G P P + W G+ + +D ++ + + L I G + C A +
Sbjct: 626 EGVNLSCEAMGDPKPEVHWYFKGRHLLNDYKYQVGQDSKFLYIRDATHHDEGTYECRAMS 685
Query: 737 DAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNA-SGNPYPQLKWAKGGSLIFD 913
AG L + TPP V + + + G+ ++ C G P+P+++W K G +
Sbjct: 686 QAGQARDTTDLMLATPPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIK 745
Query: 914 SPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDGIDMS 1093
D I + +L I K D G Y+C N AG ++ V P I +
Sbjct: 746 PDD--YIKINEGQLHIMGAKDEDAGAYSCVGENMAGKDVQVANLSVGRVPTIIES--PHT 801
Query: 1094 PRLPAQQSLTLQCLAQGKPVPQMRWTLNGTAL-THSTPGITVASDSTFIQINNVSLSDKG 1270
R+ ++ +TLQCLA G P P++ W L T + P T +D + I + + D+G
Sbjct: 802 VRVNIERQVTLQCLAVGIPPPEIEWQKGNVLLATLNNPRYTQLADGNLL-ITDAQIEDQG 860
Query: 1271 VYTCYAENVAG--SDNLMYNVDVVQAPVISN-GGTKQVIEGELAVIECLVE-GYPAPQVS 1438
+TC A N G S + V + +PV+ + +Q+IEG+ + C+V G P P +
Sbjct: 861 QFTCIARNTYGQQSQSTTLMVTGLVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIV 920
Query: 1439 WLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSP 1618
W+++ VE G ++ G +L + D G Y C A + AG++ ++++ P
Sbjct: 921 WIKDDKPVEEGPT-IKIEGGGSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKP 979
Query: 1619 KIITSTPG--VLTPS-------------------SGSKFSLPCAVRGYPDPIISWTLNGN 1735
+ + G V P+ G F++PC V G P PII+W L+G
Sbjct: 980 EFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEGFAIPCVVSGTPPPIITWYLDGR 1039
Query: 1736 DIKDGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKISTSGN 1912
I T+ AD TL + KA++ + +Y C A N AG + + ++ + P IS
Sbjct: 1040 PITPNSRDFTVTADNTLIVRKADKSYSGVYTCQATNSAGDNEQKTTIRIMNTPMISP--- 1096
Query: 1913 RYINGSEGTETVIKCXXXXXXXXXXXXKNGVPLL----PSNNLIFSEDYKLIKILSTRLS 2080
G V+ K + L P + +ED L I + +
Sbjct: 1097 ----GQSSFNMVVDDLFTIPCDVYGDPKPVITWLLDDKPFTEGVVNEDGSLT-IPNVNEA 1151
Query: 2081 DQGEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAIT 2260
+G ++C A N AGN T+ L V P I + ++ + D + L C A +P P
Sbjct: 1152 HRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAENQEKIALQNDDIVLECPAKALPPPVRL 1211
Query: 2261 WYKDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPP 2440
W + E + + + T + +++ ++ GV+ C+ N L V P
Sbjct: 1212 WTYEGEKIDSQLIPHTIR-EDGALVLQNVKLENTGVFVCQVSNLAGEDSLSYTLTVHEKP 1270
Query: 2441 EVVPERMNVSTNPRQ-TVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQI--LGTTLAIR 2611
+++ E V + T+ + C ATG+PE + +W ++ + +K+ + LGT L I
Sbjct: 1271 KIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVDNLGT-LRIY 1329
Query: 2612 NVLPDDDGFYHCIAKSDAGQKIATRKLIVNKP---------------SDRPAPIWVECDE 2746
+D G Y+C+ ++AG T + V +P DR + ++C
Sbjct: 1330 EADKNDIGNYNCVVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAVVGDR---VELKCYV 1386
Query: 2747 KGKPKKTEYMIDRG-----DTP-----DDNPQLLPWKDVEDSSLNGSIAYRCMPGPRSSR 2896
+ P + RG DT D ++ VED+++ A ++
Sbjct: 1387 EASPPASVTWFRRGIAIGTDTKGYVVESDGTLVIQSASVEDATIYTCKASNPAGKAEANL 1446
Query: 2897 TVLLHAAPQFIVKPKNTTAAIGAI--VELRCSAAGPPHPTITWAKDGKLIEDSKFEIAYS 3070
V + A+P T +I L C P P I+W + K + D K S
Sbjct: 1447 QVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTS 1506
Query: 3071 HLKVTLN----STSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITC 3238
K L+ +DSG Y C+A+N+ G + S + V I+P S K
Sbjct: 1507 DDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEV---IVPLNLDESKYKKKVFA-- 1561
Query: 3239 YERNQAYSRG----------LTWEYNG--VPMPKNLAGIHFMNNGSLVILDTSSLK-EGD 3379
+ + + G + W +G V K G N+G + D+ S+K EG+
Sbjct: 1562 -KEGEEVTLGCPVSGFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQEGN 1620
Query: 3380 LELYTCKVRNRRRHSIPHLTSAFEGVPEVKTIDKVEVNNGDSVVLDCEVT--SDPLTTHV 3553
Y C +++ + + VP V D +EV G + L C++ SD TT V
Sbjct: 1621 ---YHCVAQSKGNILDIDVELSVLAVPIVGEDDNLEVFLGKDISLSCDLQTESDDKTTFV 1677
Query: 3554 VWTKNDQKMLDDDAIYXXXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNVYE 3724
+ D+ + + G Y C +NS GKA L+V E
Sbjct: 1678 WSINGSESDRPDNVQIPSDGHRLYITDAKPENNGKYMCRVTNSAGKAERTLTLDVLE 1734
Score = 309 bits (792), Expect = 4e-82
Identities = 333/1324 (25%), Positives = 536/1324 (40%), Gaps = 97/1324 (7%)
Frame = +2
Query: 23 DVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVL 202
++ WT+ G + N T I +V D G Y C A N GG ++ LD++
Sbjct: 550 EIRWTRYGATV-FNGPNTERNPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMRLDIM 608
Query: 203 SPPEFDIHGTQPTIK-REGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDI 379
PP + REG + L+C E + D +V W R L D +
Sbjct: 609 EPPSVKVTPQDVYFNMREG--VNLSC-----EAMGDPKPEVHWYFKGRHLLNDY--KYQV 659
Query: 380 SDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQ 559
D + L I A+ + G Y C A+++AG+A + + +PP ++I +N + V
Sbjct: 660 GQDSKFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKM--MVGRGD 717
Query: 560 PTIMRC-AVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSCVAEN 736
C + G P P I+W KNGK++ ++ + +GQ L I+ + AG +SCV EN
Sbjct: 718 RVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQ-LHIMGAKDEDAGAYSCVGEN 776
Query: 737 DAGVKELEMVLDVFTPPVVSVKSDNPIKA-LGETITLFCNASGNPYPQLKWAKGGSLIFD 913
AG L V P + ++S + ++ + +TL C A G P P+++W KG L+
Sbjct: 777 MAGKDVQVANLSVGRVPTI-IESPHTVRVNIERQVTLQCLAVGIPPPEIEWQKGNVLLAT 835
Query: 914 SPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDV--LVPPEINRDGID 1087
+ L L I + D G +TC A N G S ++ V LV P + +
Sbjct: 836 LNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVSPVLGH--VP 893
Query: 1088 MSPRLPAQQSLTLQC-LAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLSD 1264
+L Q LTL C + G P P + W + + P I + + +++ + D
Sbjct: 894 PEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEG-PTIKIEGGGSLLRLRGGNPKD 952
Query: 1265 KGVYTCYAENVAGSDNLMYNVDVVQAP-----------------------VISNGGTKQV 1375
+G YTC A + AG+ L NV +++ P V T V
Sbjct: 953 EGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDV 1012
Query: 1376 IEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLC 1555
++GE I C+V G P P ++W +G + + VT L + +A SG+Y C
Sbjct: 1013 LDGEGFAIPCVVSGTPPPIITWYLDGRPITPNSRDFT-VTADNTLIVRKADKSYSGVYTC 1071
Query: 1556 SATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSS--GSKFSLPCAVRGYPDPIISWTLN 1729
ATN AG +Q T+ ++ +P I +PG + + F++PC V G P P+I+W L+
Sbjct: 1072 QATNSAGDNEQKTTIRIMNTPMI---SPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLD 1128
Query: 1730 GNDIKDGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKISTS 1906
+G + DG+L I E H + C A+N AG DT + P I+
Sbjct: 1129 DKPFTEG----VVNEDGSLTIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAE 1184
Query: 1907 GNRYINGSEGTETVIKCXXXX-----XXXXXXXXKNGVPLLPSNNLIFSEDYKLIKILST 2071
I + + V++C K L+P ED L+ + +
Sbjct: 1185 NQEKI-ALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHT---IREDGALV-LQNV 1239
Query: 2072 RLSDQGEYSCTAANKAGNATQKTNLNVGVAPKIM-ERPRTQVVHKGDQVTLWCEASGVPQ 2248
+L + G + C +N AG + L V PKI+ E P V KG + + C A+GVP+
Sbjct: 1240 KLENTGVFVCQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPE 1299
Query: 2249 PAITWYKDNELLTNTGVDETATTKKKSV-------IFSSISPSQAGVYTCKAENWVASTE 2407
TW K+ G+D KK SV I+ + + G Y C N +++
Sbjct: 1300 VIRTWNKN-------GIDLKMDEKKFSVDNLGTLRIYEA-DKNDIGNYNCVVTNEAGTSQ 1351
Query: 2408 EDIDLIVMIPPEVVPE-RMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQ 2584
+ V PP ++P + N + V L C P ++W R IAI + K
Sbjct: 1352 MTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFR-RGIAIGTDTKGY 1410
Query: 2585 ILGT--TLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVNKPSD--RPAPIWVECDEKG 2752
++ + TL I++ +D Y C A + AG+ A ++ V D P + E ++
Sbjct: 1411 VVESDGTLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESIKES 1470
Query: 2753 KPKKTEYMIDRGDTP------DDNPQL---LPWKDVED--------SSLNGSIAYRCM-- 2875
P + P +D P + WK +D + + S Y+C+
Sbjct: 1471 HPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVAR 1530
Query: 2876 ----PGPRSSRT-VLLHAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLI 3040
G +S + V++ K A G V L C +G P P I W DG ++
Sbjct: 1531 NAAGEGSKSFQVEVIVPLNLDESKYKKKVFAKEGEEVTLGCPVSGFPVPQINWVVDGTVV 1590
Query: 3041 EDSK--FEIAYSHLKVTLN----STSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKP 3202
E K S+ +TL+ S G Y C+AQ S I+V+ ++L P
Sbjct: 1591 EPGKKYKGATLSNDGLTLHFDSVSVKQEGNYHCVAQ----SKGNILDIDVELSVLAVPIV 1646
Query: 3203 SSNQ-------KNVAVITCYERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNG-SLVILDT 3358
+ K++++ + W NG + + ++G L I D
Sbjct: 1647 GEDDNLEVFLGKDISLSCDLQTESDDKTTFVWSINGSESDRP-DNVQIPSDGHRLYITDA 1705
Query: 3359 SSLKEGDLELYTCKVRN-----RRRHSIPHLTSAFEGVPEVKTIDKVEVNNGDSVVLDCE 3523
G Y C+V N R ++ L P + K+ NN ++L C+
Sbjct: 1706 KPENNGK---YMCRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLIGNN--PIILQCQ 1760
Query: 3524 VTSDPLTTHVVWTKN----DQKMLDDDAIYXXXXXXXXXXXXEKYDEGVYKCVASNSIGK 3691
VT +P T V+W + D+ L D+++ + C A N G
Sbjct: 1761 VTGNPKPT-VIWKIDGNDVDKSWLFDESLSLLRIEKLTGKSAQ------ISCTAENKAGT 1813
Query: 3692 AFDD 3703
A D
Sbjct: 1814 ASRD 1817
Score = 298 bits (764), Expect = 7e-79
Identities = 292/1171 (24%), Positives = 480/1171 (40%), Gaps = 71/1171 (6%)
Frame = +2
Query: 542 QVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWS 721
Q V + + C V +I W+K G+++ V I AG++
Sbjct: 439 QEFVGRDLNLSCTVESASAYTIYWVKTGEDIIGGPLFYHNTDTSVWTIPELSLKDAGEYE 498
Query: 722 CVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGS 901
C ++ G ++ ++ P N LGE L C+ +++W + G+
Sbjct: 499 CRVISNNGNYSVKTRVETRESPPEIFGVRNVSVPLGEAAFLHCSTRSAGEVEIRWTRYGA 558
Query: 902 LIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDG 1081
+F+ P+ R G L I H+ + D G Y C A NA G S + +D++ PP +
Sbjct: 559 TVFNGPNTERNPTNGT-LKIHHVTRADAGVYECMARNAGGMSTRKMRLDIMEPPSVKVTP 617
Query: 1082 IDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLS 1261
D+ + ++ + L C A G P P++ W G L + V DS F+ I + +
Sbjct: 618 QDVYFNM--REGVNLSCEAMGDPKPEVHWYFKGRHLLNDYK-YQVGQDSKFLYIRDATHH 674
Query: 1262 DKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVI-EGELAVIEC-LVEGYPAPQV 1435
D+G Y C A + AG ++ + P + K ++ G+ EC + G P P++
Sbjct: 675 DEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKI 734
Query: 1436 SWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVS 1615
W +NG + ++ + +G+ L I+ A+ D+G Y C N AG Q L V
Sbjct: 735 RWFKNGKDLIKPDDYIK-INEGQ-LHIMGAKDEDAGAYSCVGENMAGKDVQVANLSVGRV 792
Query: 1616 PKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENG--HTIGADGTLH 1789
P II S P + + + +L C G P P I W GN + N +T ADG L
Sbjct: 793 PTIIES-PHTVRVNIERQVTLQCLAVGIPPPEIEWQ-KGNVLLATLNNPRYTQLADGNLL 850
Query: 1790 IEKAE-ERHLIYECTAKNDAG--ADTLEFPVQTIVAPKIS--TSGNRYINGSEGTETVIK 1954
I A+ E + C A+N G + + V +V+P + + I G + T + +
Sbjct: 851 ITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVSPVLGHVPPEEQLIEGQDLTLSCV- 909
Query: 1955 CXXXXXXXXXXXXKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQ 2134
K+ P+ + L+++ D+G+Y+C A + AGN+T
Sbjct: 910 VVLGTPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEGKYTCIAVSPAGNSTL 969
Query: 2135 KTNLNVGVAPKIMERPRTQVVHK----------------------GDQVTLWCEASGVPQ 2248
N+ + P+ + +P +V K G+ + C SG P
Sbjct: 970 HINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEGFAIPCVVSGTPP 1029
Query: 2249 PAITWYKDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIV 2428
P ITWY D +T D T T ++I S +GVYTC+A N E+ + +
Sbjct: 1030 PIITWYLDGRPITPNSRDFTVTADN-TLIVRKADKSYSGVYTCQATNSAGDNEQKTTIRI 1088
Query: 2429 MIPPEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQN--NEKYQILGTTL 2602
M P + P + + + + C+ G P+PVI+W+ D + NE +L
Sbjct: 1089 MNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLDDKPFTEGVVNE-----DGSL 1143
Query: 2603 AIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVN-----------KPSDRPAPIWVECDEK 2749
I NV G + C A++ AG T L V+ K + + I +EC K
Sbjct: 1144 TIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAENQEKIALQNDDIVLECPAK 1203
Query: 2750 GKPKKTEYMIDRGDTPDDNPQLLPWKDVEDSS-------LNGSIAYRC----MPGPRS-S 2893
P G+ D QL+P ED + L + + C + G S S
Sbjct: 1204 ALPPPVRLWTYEGEKIDS--QLIPHTIREDGALVLQNVKLENTGVFVCQVSNLAGEDSLS 1261
Query: 2894 RTVLLHAAPQFIVK-PKNTTAAIGAIVELRCSAAGPPHPTITWAKDG--KLIEDSKFEI- 3061
T+ +H P+ I + P G +E+ C A G P TW K+G +++ KF +
Sbjct: 1262 YTLTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVD 1321
Query: 3062 AYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVI--- 3232
L++ +D G Y C+ N G+S ++ ++V P PS+ N AV+
Sbjct: 1322 NLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHVDVQEP--PIILPSTQTNNTAVVGDR 1379
Query: 3233 ---TCYERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKV 3403
CY + +TW G+ + + G ++G+LVI S D +YTCK
Sbjct: 1380 VELKCYV-EASPPASVTWFRRGIAIGTDTKGYVVESDGTLVI---QSASVEDATIYTCKA 1435
Query: 3404 RNRRRHSIPHLTSAFEGVPEVKTIDKV---EVNNGDSVVLDCEVTSDPLTTHVVWTKNDQ 3574
N + +L P++K D V + L C V S+PL + W ND+
Sbjct: 1436 SNPAGKAEANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPL-PQISWYLNDK 1494
Query: 3575 KMLDDDAIYXXXXXXXXXXXXEK--YDEGVYKCVASNSIGKAFDDTQLNVYEGDFLPLTG 3748
++DD + + D GVYKCVA N+ G+ Q+ V +PL
Sbjct: 1495 PLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEV----IVPL-- 1548
Query: 3749 FEGSGINIDDSSNAGGSSRREAYKKENEDAS 3841
N+D+S +++ + KE E+ +
Sbjct: 1549 ------NLDES-----KYKKKVFAKEGEEVT 1568
Score = 265 bits (678), Expect = 6e-69
Identities = 294/1175 (25%), Positives = 469/1175 (39%), Gaps = 79/1175 (6%)
Frame = +2
Query: 254 GDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGD--LTDNVDISDDGRKLTISQASLEN 427
G + L+C ++ A + W K + G N D S TI + SL++
Sbjct: 443 GRDLNLSCTVESAS-----AYTIYWVKTGEDIIGGPLFYHNTDTS----VWTIPELSLKD 493
Query: 428 AGLYTCIALNRAGEASLEFKVEIL-SPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPS 604
AG Y C ++ G S++ +VE SPP I RN V + + + C+
Sbjct: 494 AGEYECRVISNNGNYSVKTRVETRESPPEIFGVRN---VSVPLGEAAFLHCSTRSAGEVE 550
Query: 605 IKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTP 784
I+W + G V + N L+I AG + C+A N G+ +M LD+ P
Sbjct: 551 IRWTRYGATVFNGPNTERNPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMRLDIMEP 610
Query: 785 PVVSVKSDNPIKALGETITLFCNASGNPYPQLKW-AKGGSLIFDSPDGARISLKGARLDI 961
P V V + + E + L C A G+P P++ W KG L+ D ++ L I
Sbjct: 611 PSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLLNDYK--YQVGQDSKFLYI 668
Query: 962 PHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQC-LA 1138
D G Y C+A++ AG + + + + PP++ + I + ++ +C
Sbjct: 669 RDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKV--EIIQNKMMVGRGDRVSFECKTI 726
Query: 1139 QGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLM 1318
+GKP P++RW NG L P + + + I D G Y+C EN+AG D +
Sbjct: 727 RGKPHPKIRWFKNGKDLI--KPDDYIKINEGQLHIMGAKDEDAGAYSCVGENMAGKDVQV 784
Query: 1319 YNVDVVQAP-VISNGGTKQVIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRY-- 1489
N+ V + P +I + T +V ++CL G P P++ W + GN + + RY
Sbjct: 785 ANLSVGRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEW-QKGNVLLATLNNPRYTQ 843
Query: 1490 VTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEV--LVSPKIITSTPGVLTPSSG 1663
+ DG +L I +A+ D G + C A N G Q+ TL V LVSP ++ P G
Sbjct: 844 LADGNLL-ITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVSP-VLGHVPPEEQLIEG 901
Query: 1664 SKFSLPC-AVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKAEER-HLIYECTAK 1837
+L C V G P P I W + +++G G L + + Y C A
Sbjct: 902 QDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEGKYTCIAV 961
Query: 1838 NDAGADTLEFPVQTIVAPK--------------ISTSGNRYINGSEGTETV-------IK 1954
+ AG TL VQ I P+ IS +++ T V I
Sbjct: 962 SPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEGFAIP 1021
Query: 1955 CXXXXX-XXXXXXXKNGVPLLP-SNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNA 2128
C +G P+ P S + + D LI + S G Y+C A N AG+
Sbjct: 1022 CVVSGTPPPIITWYLDGRPITPNSRDFTVTADNTLI-VRKADKSYSGVYTCQATNSAGDN 1080
Query: 2129 TQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDET 2308
QKT + + P I + + D T+ C+ G P+P ITW D++ T V+E
Sbjct: 1081 EQKTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLDDKPFTEGVVNED 1140
Query: 2309 ATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQT 2488
S+ +++ + G +TC A+N + + L V P + E
Sbjct: 1141 G-----SLTIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAENQEKIALQNDD 1195
Query: 2489 VFLSCNATGIPEPVISWMRDSNIAIQNNEKYQIL-GTTLAIRNVLPDDDGFYHCIAKSDA 2665
+ L C A +P PV W + + I L ++NV ++ G + C + A
Sbjct: 1196 IVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDGALVLQNVKLENTGVFVCQVSNLA 1255
Query: 2666 GQKIATRKLIVN-KP---SDRPA--------PIWVECDEKGKPKKTEYMIDRG-----DT 2794
G+ + L V+ KP S+ P I + C G P+ G D
Sbjct: 1256 GEDSLSYTLTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDE 1315
Query: 2795 PDDNPQLLPWKDVEDSSLNGSIAYRCM---PGPRSSRTVLLHAAPQFIVKPK---NTTAA 2956
+ L + ++ N Y C+ S T + I+ P N TA
Sbjct: 1316 KKFSVDNLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAV 1375
Query: 2957 IGAIVELRCSAAGPPHPTITWAKDGKLI-EDSKFEIAYSHLKVTLNSTS--DSGEYTCMA 3127
+G VEL+C P ++TW + G I D+K + S + + S S D+ YTC A
Sbjct: 1376 VGDRVELKCYVEASPPASVTWFRRGIAIGTDTKGYVVESDGTLVIQSASVEDATIYTCKA 1435
Query: 3128 QNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITCYERNQAYSRGLTWEYNGVPMPKN 3307
N G + + N+ T S + K+ V+T +++ L P+P+
Sbjct: 1436 SNPAGKA--------EANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQ- 1486
Query: 3308 LAGIHFMNNGSLVILDTSSLKEGD----LELYTCKVRNRRRHSIPHLTSAFEG------- 3454
I + N +I D +S K D L ++ K+ + + +A EG
Sbjct: 1487 ---ISWYLNDKPLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVE 1543
Query: 3455 ------VPEVKTIDKVEVNNGDSVVLDCEVTSDPL 3541
+ E K KV G+ V L C V+ P+
Sbjct: 1544 VIVPLNLDESKYKKKVFAKEGEEVTLGCPVSGFPV 1578
>gi|7499207|pir||T20992 hypothetical protein F15G9.4a - Caenorhabditis
elegans
gi|3875955|emb|CAA87335.1| C. elegans HIM-4 protein (corresponding
sequence F15G9.4a) [Caenorhabditis elegans]
gi|3879657|emb|CAA87344.1| C. elegans HIM-4 protein (corresponding
sequence F15G9.4a) [Caenorhabditis elegans]
Length = 5175
Score = 3091 bits (8013), Expect = 0.0
Identities = 1524/1601 (95%), Positives = 1524/1601 (95%)
Frame = +2
Query: 2 ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH 181
ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH
Sbjct: 3598 ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH 3657
Query: 182 DFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDL 361
DFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDL
Sbjct: 3658 DFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDL 3717
Query: 362 TDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQP 541
TDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQP
Sbjct: 3718 TDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQP 3777
Query: 542 QVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWS 721
QVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWS
Sbjct: 3778 QVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWS 3837
Query: 722 CVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGS 901
CVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGS
Sbjct: 3838 CVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGS 3897
Query: 902 LIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDG 1081
LIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDG
Sbjct: 3898 LIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDG 3957
Query: 1082 IDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLS 1261
IDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLS
Sbjct: 3958 IDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLS 4017
Query: 1262 DKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVIEGELAVIECLVEGYPAPQVSW 1441
DKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVIEGELAVIECLVEGYPAPQVSW
Sbjct: 4018 DKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVIEGELAVIECLVEGYPAPQVSW 4077
Query: 1442 LRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPK 1621
LRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPK
Sbjct: 4078 LRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPK 4137
Query: 1622 IITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKA 1801
IITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKA
Sbjct: 4138 IITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKA 4197
Query: 1802 EERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCXXXXXXXX 1981
EERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKC
Sbjct: 4198 EERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCEIESESSE 4257
Query: 1982 XXXXKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVA 2161
KNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVA
Sbjct: 4258 FSWSKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVA 4317
Query: 2162 PKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATTKKKSVIFS 2341
PKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATTKKKSVIFS
Sbjct: 4318 PKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATTKKKSVIFS 4377
Query: 2342 SISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFLSCNATGIP 2521
SISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFLSCNATGIP
Sbjct: 4378 SISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFLSCNATGIP 4437
Query: 2522 EPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVN 2701
EPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVN
Sbjct: 4438 EPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVN 4497
Query: 2702 KPSDRPAPIWVECDEKGKPKKTEYMIDRGDTPDDNPQLLPWKDVEDSSLNGSIAYRCMPG 2881
KPSDRPAPIWVECDEKGKPKKTEYMIDRGDTPDDNPQLLPWKDVEDSSLNGSIAYRCMPG
Sbjct: 4498 KPSDRPAPIWVECDEKGKPKKTEYMIDRGDTPDDNPQLLPWKDVEDSSLNGSIAYRCMPG 4557
Query: 2882 PRSSRTVLLHAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEI 3061
PRSSRTVLLHAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEI
Sbjct: 4558 PRSSRTVLLHAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEI 4617
Query: 3062 AYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITCY 3241
AYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITCY
Sbjct: 4618 AYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITCY 4677
Query: 3242 ERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRH 3421
ERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRH
Sbjct: 4678 ERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRH 4737
Query: 3422 SIPHLTSAFEGVPEVKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIY 3601
SIPHLTSAFEGVPEVKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIY
Sbjct: 4738 SIPHLTSAFEGVPEVKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIY 4797
Query: 3602 XXXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNVYEGDFLPLTGFEGSGINIDDS 3781
EKYDEGVYKCVASNSIGKAFDDTQLNVY
Sbjct: 4798 VLPNNSLVLLNVEKYDEGVYKCVASNSIGKAFDDTQLNVY-------------------- 4837
Query: 3782 SNAGGSSRREAYKKENEDASXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAKQYPTDDYH 3961
GGSSRREAYKKENEDAS AKQYPTDDYH
Sbjct: 4838 ---GGSSRREAYKKENEDASTTTITTTSPTTTTTETPLTTTIIPALITLPAKQYPTDDYH 4894
Query: 3962 EGSANDDGFGPTTQDSLFEFNPPLHPEISVVNTDCAGTINENGDCVDKDGKTHNLKILTG 4141
EGSANDDGFGPTTQDSLFEFNPPLHPEISVVNTDCAGTINENGDCVDKDGKTHNLKILTG
Sbjct: 4895 EGSANDDGFGPTTQDSLFEFNPPLHPEISVVNTDCAGTINENGDCVDKDGKTHNLKILTG 4954
Query: 4142 ENHCPEGFAMNPHTRICEDLDECAFYQPCDFECINYDGGFQCNCPLGYELAEEGCRDVNE 4321
ENHCPEGFAMNPHTRICEDLDECAFYQPCDFECINYDGGFQCNCPLGYELAEEGCRDVNE
Sbjct: 4955 ENHCPEGFAMNPHTRICEDLDECAFYQPCDFECINYDGGFQCNCPLGYELAEEGCRDVNE 5014
Query: 4322 CESVRCEDGKACFNQLGGYECIDDPCPANYSLVDDRYCEPECENCTSTPIQVHMLAIPSG 4501
CESVRCEDGKACFNQLGGYECIDDPCPANYSLVDDRYCEPECENCTSTPIQVHMLAIPSG
Sbjct: 5015 CESVRCEDGKACFNQLGGYECIDDPCPANYSLVDDRYCEPECENCTSTPIQVHMLAIPSG 5074
Query: 4502 LPISHIATLTAYDKSGRVLNDTTYAISDTGAPLARGRMTSGPFTIKAVKRGHAQVWTNRV 4681
LPISHIATLTAYDKSGRVLNDTTYAISDTGAPLARGRMTSGPFTIKAVKRGHAQVWTNRV
Sbjct: 5075 LPISHIATLTAYDKSGRVLNDTTYAISDTGAPLARGRMTSGPFTIKAVKRGHAQVWTNRV 5134
Query: 4682 LAAGDHHKVRVRAHSDHATNELHAPKETNFLVLINVGQYPF 4804
LAAGDHHKVRVRAHSDHATNELHAPKETNFLVLINVGQYPF
Sbjct: 5135 LAAGDHHKVRVRAHSDHATNELHAPKETNFLVLINVGQYPF 5175
Score = 424 bits (1089), Expect = e-116
Identities = 351/1291 (27%), Positives = 547/1291 (42%), Gaps = 61/1291 (4%)
Frame = +2
Query: 5 SGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHD 184
+G P P +++ K+G +N +D I+ T I+N Q +GRYTC A N+ G++ D
Sbjct: 2878 TGTPPPTILFMKDGKRLNESDEVDII---GSTLVIDNPQKEVEGRYTCIAENKAGRSEKD 2934
Query: 185 FSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLT 364
++VL PP+ + + GD +TL CPI ED + + ++W++ DG L
Sbjct: 2935 MMVEVLLPPKLSKEWINVEV-QAGDPLTLECPI---EDTSG--VHITWSRQF-GKDGQLD 2987
Query: 365 DNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVI---DISRNDV 535
S D KL I QA+ E+A Y+CIA+N AG A F+V + +PP I S ++
Sbjct: 2988 MRAQSSSDKSKLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEI 3047
Query: 536 QPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGK 715
+ P C G P P I W +GK + + + + L+I + G+
Sbjct: 3048 VADTTLEIP----CRTEGIPPPEISWFLDGKPILEMPGVTYKQGDLSLRIDNIKPNQEGR 3103
Query: 716 WSCVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKG 895
++CVAEN AG E + +++ PP V + S+ G T+ C GNP P + W K
Sbjct: 3104 YTCVAENKAGRAEQDTYVEISEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKD 3163
Query: 896 GSLIFDSPDGARISLKGARLDIPHLKKT---DVGDYTCQALNAAGTSEASVSVDVLVPPE 1066
G P + + +L HL++T D G YTC A N AG S+ + V+VLVPP
Sbjct: 3164 G-----EPYTSDLLQFSTKLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEVLVPPR 3218
Query: 1067 INRDGIDMSPRLPAQQSLT--LQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQ 1240
I D L ++ T + C G+PVP + W NG + P +
Sbjct: 3219 IE----DEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEIEQFNP---------VLH 3265
Query: 1241 INNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVI-SNGGTKQVIEGELAVIECLVEG 1417
I N + +D+G Y+C A N AG+ + +DV P ++ T ++EGE A IEC ++G
Sbjct: 3266 IRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNIVEGESAKIECKIDG 3325
Query: 1418 YPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYT 1597
+P P +SWL+ G + + G L I++A+ D G+Y C ATN G ++Q +
Sbjct: 3326 HPKPTISWLKGGR--PFNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFK 3383
Query: 1598 LEVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGAD 1777
+ V P I + +G + L C V G P P ++W G+D ++ HTI +
Sbjct: 3384 VNVYTKPYIDETIDQTPKAVAGGEIILKCPVLGNPTPTVTWK-RGDDAVPNDSRHTIVNN 3442
Query: 1778 GTLHIEK-AEERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIK 1954
L I E Y C A N+AG T + + I P G E +
Sbjct: 3443 YDLKINSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMD 3502
Query: 1955 CXXXXXXXXXXXXKNG-VPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNAT 2131
C G P+ + S D I I +LSD G+Y C A+N+AG +
Sbjct: 3503 CGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAKLSDGGKYICRASNEAGTSD 3562
Query: 2132 QKTNLNVGVAPK-----IMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTG 2296
L + V PK I+ P V + L C SG+PQP + W K+ + T
Sbjct: 3563 IDLILKILVPPKIDKSNIIGNPLAIVAR---TIYLECPISGIPQPDVIWTKNGMDINMTD 3619
Query: 2297 VDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEV-VPERMNVST 2473
++ ++ + G YTC A N D L V+ PPE +
Sbjct: 3620 SRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIK 3679
Query: 2474 NPRQTVFLSCN---ATGIPEPV--ISWMRDSNIA---IQNNEKYQILGTTLAIRNVLPDD 2629
T+ L+C A I + V +SW +DS + +N G L I ++
Sbjct: 3680 REGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDGRKLTISQASLEN 3739
Query: 2630 DGFYHCIAKSDAGQKIATRKLIVNKP--------SDRP-----APIWVECDEKGKPKKTE 2770
G Y CIA + AG+ K+ + P +P P + C G P +
Sbjct: 3740 AGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSI 3799
Query: 2771 YMIDRGD--TPDDNPQLLPWKDV-------EDSSLNGSIAYRCMPGPRSSRTVL-LHAAP 2920
+ G T D+N +++ V D + S G + VL + P
Sbjct: 3800 KWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPP 3859
Query: 2921 QFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDS----KFEIAYSHLKVTL 3088
VK N A+G + L C+A+G P+P + WAK G LI DS + + + L +
Sbjct: 3860 VVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGSLIFDSPDGARISLKGARLDIPH 3919
Query: 3089 NSTSDSGEYTCMAQNSVGSSTVSAFINV-------DNNILPTPKPSSNQKNVAVITCYER 3247
+D G+YTC A N+ G+S S ++V + I +P+ + Q + C +
Sbjct: 3920 LKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQS--LTLQCLAQ 3977
Query: 3248 NQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRHSI 3427
+ + + W NG + + GI ++ + + ++ SL D +YTC N
Sbjct: 3978 GKPVPQ-MRWTLNGTALTHSTPGITVASDSTFIQINNVSL--SDKGVYTCYAENVAGSDN 4034
Query: 3428 PHLTSAFEGVPEVKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLD--DDAIY 3601
P + +V G+ V++C V P V W +N ++ Y
Sbjct: 4035 LMYNVDVVQAPVISNGGTKQVIEGELAVIECLVEGYP-APQVSWLRNGNRVETGVQGVRY 4093
Query: 3602 XXXXXXXXXXXXEKYDEGVYKCVASNSIGKA 3694
D G+Y C A+N G A
Sbjct: 4094 VTDGRMLTIIEARSLDSGIYLCSATNEAGSA 4124
Score = 411 bits (1057), Expect = e-113
Identities = 345/1302 (26%), Positives = 553/1302 (41%), Gaps = 63/1302 (4%)
Frame = +2
Query: 2 ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH 181
++G P P V W +NG +I Q N I N D+G+Y+C A+N G A
Sbjct: 3240 VTGRPVPYVTWKRNGKEIE---------QFNPVLHIRNATRADEGKYSCIASNEAGTAVA 3290
Query: 182 DFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDL 361
DF +DV + P F+ H T I EG++ + C I +SW K R +
Sbjct: 3291 DFLIDVFTKPTFETHETTFNIV-EGESAKIECKID-----GHPKPTISWLKGGRPFN--- 3341
Query: 362 TDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQP 541
DN+ +S G L I +A + GLYTC+A N G++ +FKV + + P ID D P
Sbjct: 3342 MDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYID-ETIDQTP 3400
Query: 542 QVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWS 721
+ I++C V G+P P++ W + V +D IV L+I ++ AG++S
Sbjct: 3401 KAVAGGEIILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNNYD-LKINSVTTEDAGQYS 3459
Query: 722 CVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKAL-GETITLFCNASGNPYPQLKWAKGG 898
C+A N+AG +V P K N + + +TIT+ C + P P + W +G
Sbjct: 3460 CIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPSISWFRGD 3519
Query: 899 SLIF------DSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVP 1060
++ SPDG+ I++ A+L +D G Y C+A N AGTS+ + + +LVP
Sbjct: 3520 KPVYLYDRYSISPDGSHITINKAKL-------SDGGKYICRASNEAGTSDIDLILKILVP 3572
Query: 1061 PEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQ 1240
P+I++ I +P +++ L+C G P P + WT NG + + + +A ++
Sbjct: 3573 PKIDKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFG 3632
Query: 1241 INNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVI--EGELAVIECLVE 1414
I NV ++D+G YTC A N G + +++DV+ P GT+ I EG+ + C ++
Sbjct: 3633 IENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIK 3692
Query: 1415 -----GYPAPQVSWLRNGNRVETGV-QGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAG 1576
VSW ++ ++ + V DGR LTI +A ++G+Y C A N AG
Sbjct: 3693 LAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDGRKLTISQASLENAGLYTCIALNRAG 3752
Query: 1577 SAQQAYTLEVLVSPKIITSTPGVLTP--SSGSKFSLPCAVRGYPDPIISWTLNGNDIKDG 1750
A + +E+L SP +I + + P + + CAV G+P P I W NG ++ D
Sbjct: 3753 EASLEFKVEIL-SPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDD 3811
Query: 1751 ENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYING 1927
EN + L I + + H + C A+NDAG LE + P +S + I
Sbjct: 3812 ENIRIVEQGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKA 3871
Query: 1928 SEGTETVIKCXXXXXXXXXXXXKNGVPLLPSNNLIF-SEDYKLIKILSTRL-------SD 2083
T T+ K G +LIF S D I + RL +D
Sbjct: 3872 LGETITLFCNASGNPYPQLKWAKGG-------SLIFDSPDGARISLKGARLDIPHLKKTD 3924
Query: 2084 QGEYSCTAANKAGNATQKTNLNVGVAPKIME-----RPRTQVVHKGDQVTLWCEASGVPQ 2248
G+Y+C A N AG + +++V V P+I PR + +TL C A G P
Sbjct: 3925 VGDYTCQALNAAGTSEASVSVDVLVPPEINRDGIDMSPR---LPAQQSLTLQCLAQGKPV 3981
Query: 2249 PAITWYKDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIV 2428
P + W + LT++ T + + +++S S GVYTC AEN VA ++ + +
Sbjct: 3982 PQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAEN-VAGSDNLMYNVD 4040
Query: 2429 MIPPEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSN---IAIQNNEKYQILGTT 2599
++ V+ + + C G P P +SW+R+ N +Q +Y G
Sbjct: 4041 VVQAPVISNGGTKQVIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQ-GVRYVTDGRM 4099
Query: 2600 LAIRNVLPDDDGFYHCIAKSDAG--------QKIATRKLIVNKPS----DRPAPIWVECD 2743
L I D G Y C A ++AG + + + K+I + P + + C
Sbjct: 4100 LTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCA 4159
Query: 2744 EKGKPKK-TEYMIDRGDTPDDNPQLLPWKDVE---DSSLNGSIAYRCMPGPRSSRTVLLH 2911
+G P + ++ D D D + + + Y C + L
Sbjct: 4160 VRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKAEERHLIYEC-TAKNDAGADTLE 4218
Query: 2912 AAPQFIVKPKNTTA-------AIGAIVELRCSAAGPPHPTITWAKDGKLIEDSK---FEI 3061
Q IV PK +T+ + G ++C +W+K+G + S F
Sbjct: 4219 FPVQTIVAPKISTSGNRYINGSEGTETVIKCEIES-ESSEFSWSKNGVPLLPSNNLIFSE 4277
Query: 3062 AYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVD--NNILPTPKPSSNQKNVAVIT 3235
Y +K+ SD GEY+C A N G++T +NV I+ P+ K V
Sbjct: 4278 DYKLIKILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTL 4337
Query: 3236 CYERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRR 3415
E + +TW Y + N G+ + SS+ +YTCK N
Sbjct: 4338 WCEASGVPQPAITW-YKDNELLTN-TGVDETATTKKKSVIFSSISPSQAGVYTCKAENWV 4395
Query: 3416 RHSIPHLTSAFEGVPE-VKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDD 3592
+ + PE V V N +V L C T P + W ++ + ++
Sbjct: 4396 ASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFLSCNATGIPEPV-ISWMRDSNIAIQNN 4454
Query: 3593 AIYXXXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNV 3718
Y D+G Y C+A + G+ +L V
Sbjct: 4455 EKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIV 4496
Score = 392 bits (1008), Expect = e-107
Identities = 323/1307 (24%), Positives = 555/1307 (41%), Gaps = 59/1307 (4%)
Frame = +2
Query: 2 ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH 181
++G P P V WTK+G + S +L++ + F I + ++ +G Y C A N G A
Sbjct: 2122 VTGKPNPVVTWTKDGRPVGDLKSVQVLSEGQQ-FKIVHAEIAHKGSYICMAKNDVGTAEI 2180
Query: 182 DFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDL 361
F +D+++ P +G + CPI ++ Q++ W ++ + +D +
Sbjct: 2181 SFDVDIITRPMIQKGIKNIVTAIKGGALPFKCPIDDDKNFKGQII---WLRNYQPIDLEA 2237
Query: 362 TD-NVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQ 538
D + + R+LTI + + G Y+C N AGE S +FK +L PP I + D
Sbjct: 2238 EDARITRLSNDRRLTILNVTENDEGQYSCRVKNDAGENSFDFKATVLVPPTIIMLDKDKN 2297
Query: 539 PQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQV----LQILRTDSDH 706
+ + C TG P P I W K+G+ + + I+ G++ L+I R
Sbjct: 2298 KTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGELNGNQLKITRIKEGD 2357
Query: 707 AGKWSCVAENDAGVKELEMVLDVFTPPVVS---VKSDNPIKALGETITLFCNASGNPYPQ 877
AGK++C A+N AG E ++ ++V T P + + SD + E + + C P +
Sbjct: 2358 AGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQ-NERVVISCPVYARPPAK 2416
Query: 878 LKWAKGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLV 1057
+ W K G + S + S G +L + L++TD YTC A N AGT + V +LV
Sbjct: 2417 ITWLKAGKPL-QSDKFVKTSANGQKLYLFKLRETDSSKYTCIATNEAGTDKRDFKVSMLV 2475
Query: 1058 PPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFI 1237
P + I + + TL C A+G P P + W +G A+ + + + +
Sbjct: 2476 APSFDEPNIVRRITVNSGNPSTLHCPAKGSPSPTITWLKDGNAIEPNDRYVFFDAGRQ-L 2534
Query: 1238 QINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQV--IEGELAVIECLV 1411
QI+ SD+G YTC A N GSD+L ++V+ PVI + V IEG + + C
Sbjct: 2535 QISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIPPVIDGERREAVAVIEGFSSELFC-D 2593
Query: 1412 EGYPAPQVSWLRNGNRVET----GVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGS 1579
V W ++G + G ++ + G+ ++ + AR DSG Y C N AG
Sbjct: 2594 SNSTGVDVEWQKDGLTINQDTLRGDSFIQIPSSGKKMSFLSARKSDSGRYTCIVRNPAGE 2653
Query: 1580 AQQAYTLEVLVSPKIIT--STPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGE 1753
A++ + V P I S+ + T + C V G P P + W + ++
Sbjct: 2654 ARKLFDFAVNDPPSISDELSSANIQTIVPYYPVEINCVVSGSPHPKVYWLFDDKPLEPDS 2713
Query: 1754 NGHTIGADG-TLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYING 1927
+ + +G TL I +++ H Y C A+N+ G +F V+ P +
Sbjct: 2714 AAYELTNNGETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLVRVTAPPHFEKEREEVV-A 2772
Query: 1928 SEGTETVIKCXXXXXXXXXXXXKNGVPLLPSNNLIFSE---DYKLIKILSTRLSDQGEYS 2098
G ++ C + N +I S+ + K + + + +L D+G Y
Sbjct: 2773 RVGDTMLLTCNAESSVPLSSVYWHAHDESVQNGVITSKYAANEKTLNVTNIQLDDEGFYY 2832
Query: 2099 CTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNE 2278
CTA N+AG + L V P +++ + + G ++TL C A+G P P I + KD +
Sbjct: 2833 CTAVNEAGITKKFFKLIVIETPYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGK 2892
Query: 2279 LLTNTG-VDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPE 2455
L + VD +T ++ + G YTC AEN +E+D+ + V++PP++ E
Sbjct: 2893 RLNESDEVDIIGST----LVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKE 2948
Query: 2456 RMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILG--TTLAIRNVLPDD 2629
+NV + L C I+W R Q + + Q + L I P+D
Sbjct: 2949 WINVEVQAGDPLTLECPIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSKLYIMQATPED 3008
Query: 2630 DGFYHCIAKSDAGQKIATRKLIVNKPSD------------RPAPIWVECDEKG-KPKKTE 2770
Y CIA +DAG A ++ VN P + + C +G P +
Sbjct: 3009 ADSYSCIAVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEIS 3068
Query: 2771 YMIDRGDTPDDNPQLLPWKD----VEDSSLNGSIAYRCMPGPRSSRT-----VLLHAAPQ 2923
+ +D + D +++ N Y C+ ++ R V + P+
Sbjct: 3069 WFLDGKPILEMPGVTYKQGDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEISEPPR 3128
Query: 2924 FIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGK-----LIEDSKFEIAYSHLKVTL 3088
++ + G +RC G P P + W KDG+ L++ S +++Y HL+ T
Sbjct: 3129 VVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKDGEPYTSDLLQFST-KLSYLHLRET- 3186
Query: 3089 NSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQK-------NVAVITCYER 3247
+ +D G YTC+A N G S + D +L P+ ++ N ++ C
Sbjct: 3187 -TLADGGTYTCIATNKAGESQTTT----DVEVLVPPRIEDEERVLQGKEGNTYMVHCQVT 3241
Query: 3248 NQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRHSI 3427
+ +TW+ NG + + +H N D Y+C N ++
Sbjct: 3242 GRPVPY-VTWKRNGKEIEQFNPVLHIRN-----------ATRADEGKYSCIASNEAGTAV 3289
Query: 3428 PHLTSAFEGVPEVKTIDKV-EVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIYX 3604
P +T + + G+S ++C++ P T + W K + D+ I
Sbjct: 3290 ADFLIDVFTKPTFETHETTFNIVEGESAKIECKIDGHPKPT-ISWLKGGRPFNMDNIILS 3348
Query: 3605 XXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNVYEGDFLPLT 3745
+++D G+Y CVA+NS G + D ++NVY ++ T
Sbjct: 3349 PRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDET 3395
Score = 379 bits (973), Expect = e-103
Identities = 346/1299 (26%), Positives = 550/1299 (41%), Gaps = 70/1299 (5%)
Frame = +2
Query: 2 ISGIPQPDVIWTKNG--MDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKA 175
+SG P P + W +G ++ L+ + T ++V V +G Y C A ++G
Sbjct: 1573 VSGFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQEGNYHCVAQSKGNIL 1632
Query: 176 SHDFSLDVLSPPEFDIHGTQPTIKRE-GDTITLTCPIKLAEDIADQVMDVSWTKDSRALD 352
D L VL+ P I G ++ G I+L+C ++ D D+ V W+ + +
Sbjct: 1633 DIDVELSVLAVP---IVGEDDNLEVFLGKDISLSCDLQTESD--DKTTFV-WSINGS--E 1684
Query: 353 GDLTDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRND 532
D DNV I DG +L I+ A EN G Y C N AG+A +++L PPV +
Sbjct: 1685 SDRPDNVQIPSDGHRLYITDAKPENNGKYMCRVTNSAGKAERTLTLDVLEPPVFVEPVFE 1744
Query: 533 VQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAG 712
++ N P I++C VTG+P P++ W +G +V D++ E +L+I + A
Sbjct: 1745 ANQKLIGNNPIILQCQVTGNPKPTVIWKIDGNDV--DKSWLFDESLSLLRIEKLTGKSA- 1801
Query: 713 KWSCVAENDAGVKELEMVLDVFTPPVVSVKSD-NPIKALGETITLFCNASGNPYPQLKWA 889
+ SC AEN AG + + P + D I ETITL C S + Q+ W
Sbjct: 1802 QISCTAENKAGTASRDFFIQNIAAPTFKNEGDQETIFRESETITLDCPVSLGDF-QITWM 1860
Query: 890 KGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEI 1069
K G + + + A +L RL I + + YTC A N AG V V V P+I
Sbjct: 1861 KQGLPL--TENDAIFTLDNTRLTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQVLPKI 1918
Query: 1070 NRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINN 1249
+ + + + + L C A+G P P +W N L + V ++ T + +NN
Sbjct: 1919 KNAVVTL--EINEGEEIILTCDAEGNPTPTAKWDFNQGDLPKE--AVFVNNNHTVV-VNN 1973
Query: 1250 VSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVIEGELA---VIECLVEGY 1420
V+ GVY CYA N G NV V P +G T+ + L +EC V+
Sbjct: 1974 VTKYHTGVYKCYATNKVGQAVKTINVHVRTKPRFESGLTESELTVNLTRSITLECDVDDA 2033
Query: 1421 PAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTL 1600
+SW NG GV+ + GR L I+ A++ D G Y C+ TNEAG A + + L
Sbjct: 2034 IGVGISWTVNGKPFLAETDGVQTLAGGRFLHIVSAKTDDHGSYACTVTNEAGVATKTFNL 2093
Query: 1601 EVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADG 1780
V V P I+ + G T + LPC V G P+P+++WT +G + D ++ +
Sbjct: 2094 FVQVPPTIV-NEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEGQ 2152
Query: 1781 TLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKC 1957
I AE H Y C AKND G + F V I P I + +G KC
Sbjct: 2153 QFKIVHAEIAHKGSYICMAKNDVGTAEISFDVDIITRPMIQKGIKNIVTAIKGGALPFKC 2212
Query: 1958 ---XXXXXXXXXXXXKNGVPL---LPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKA 2119
+N P+ + + + + IL+ +D+G+YSC N A
Sbjct: 2213 PIDDDKNFKGQIIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTENDEGQYSCRVKNDA 2272
Query: 2120 GNATQKTNLNVGVAPKI--MERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNT 2293
G + V V P I +++ + + + VTL C A+G P+P ITW+KD E +
Sbjct: 2273 GENSFDFKATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIE 2332
Query: 2294 GVDE---TATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERM- 2461
+ + + + I AG YTC+A+N S E+D+++ V+ P++ + +
Sbjct: 2333 NIADIIPNGELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIP 2392
Query: 2462 -NVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNE--KYQILGTTLAIRNVLPDDD 2632
+ + + V +SC P I+W++ + +Q+++ K G L + + D
Sbjct: 2393 SDYESQQNERVVISCPVYARPPAKITWLK-AGKPLQSDKFVKTSANGQKLYLFKLRETDS 2451
Query: 2633 GFYHCIAKSDAGQKIATRK--LIVNKPSDRP-----------APIWVECDEKGKPKKTEY 2773
Y CIA ++AG K ++V D P P + C KG P T
Sbjct: 2452 SKYTCIATNEAGTDKRDFKVSMLVAPSFDEPNIVRRITVNSGNPSTLHCPAKGSPSPTIT 2511
Query: 2774 MIDRGDTPDDNPQLL---PWKDVEDSSLNGSI--AYRCMP----GPRSSRTVLLHAAPQF 2926
+ G+ + N + + + ++ S GS Y C+ G L P
Sbjct: 2512 WLKDGNAIEPNDRYVFFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIPPV 2571
Query: 2927 IVKPKNTTAAI--GAIVELRCSAAGPPHPTITWAKDGKLIE------DSKFEIAYSHLKV 3082
I + A+ G EL C + + W KDG I DS +I S K+
Sbjct: 2572 IDGERREAVAVIEGFSSELFCD-SNSTGVDVEWQKDGLTINQDTLRGDSFIQIPSSGKKM 2630
Query: 3083 TLNST--SDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITCY---ER 3247
+ S SDSG YTC+ +N G + + N P+ + N+ I Y E
Sbjct: 2631 SFLSARKSDSGRYTCIVRNPAGEA--RKLFDFAVNDPPSISDELSSANIQTIVPYYPVEI 2688
Query: 3248 NQAYSRG----LTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNR- 3412
N S + W ++ P+ + A NNG + + S ++ YTC+ +N
Sbjct: 2689 NCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIVRSQVEHAG--TYTCEAQNNV 2746
Query: 3413 ---RRHSIPHLTSA--FEGVPEVKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQK 3577
R+ + +T+ FE K ++V GD+++L C S + V W +D+
Sbjct: 2747 GKARKDFLVRVTAPPHFE-----KEREEVVARVGDTMLLTCNAESSVPLSSVYWHAHDES 2801
Query: 3578 MLDD--DAIYXXXXXXXXXXXXEKYDEGVYKCVASNSIG 3688
+ + + Y + DEG Y C A N G
Sbjct: 2802 VQNGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAG 2840
Score = 364 bits (935), Expect = 1e-98
Identities = 332/1310 (25%), Positives = 538/1310 (40%), Gaps = 75/1310 (5%)
Frame = +2
Query: 14 PQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSL 193
P + W K G + +D V + N + + ++ TD +YTC ATN G DF +
Sbjct: 2413 PPAKITWLKAGKPLQ-SDKFVKTSANGQKLYLFKLRETDSSKYTCIATNEAGTDKRDFKV 2471
Query: 194 DVLSPPEFDIHGTQPTIKRE-----GDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGD 358
+L P FD +P I R G+ TL CP K ++W KD A++ +
Sbjct: 2472 SMLVAPSFD----EPNIVRRITVNSGNPSTLHCPAK-----GSPSPTITWLKDGNAIEPN 2522
Query: 359 LTDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQ 538
D D GR+L IS+ + G YTCIA N G LE +E++ PPVID R +
Sbjct: 2523 --DRYVFFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIPPVIDGERREAV 2580
Query: 539 PQV-AVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDD-----ENIRIVEQGQVLQILRTDS 700
+ + TG ++W K+G + D I+I G+ + L
Sbjct: 2581 AVIEGFSSELFCDSNSTG---VDVEWQKDGLTINQDTLRGDSFIQIPSSGKKMSFLSARK 2637
Query: 701 DHAGKWSCVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLF------CNASG 862
+G+++C+ N AG V PP +S D A +TI + C SG
Sbjct: 2638 SDSGRYTCIVRNPAGEARKLFDFAVNDPPSIS---DELSSANIQTIVPYYPVEINCVVSG 2694
Query: 863 NPYPQLKWAKGGSLIFDS----PDGARISL--KGARLDIPHLKKTDVGDYTCQALNAAGT 1024
+P+P++ W +FD PD A L G L I + G YTC+A N G
Sbjct: 2695 SPHPKVYW------LFDDKPLEPDSAAYELTNNGETLKIVRSQVEHAGTYTCEAQNNVGK 2748
Query: 1025 SEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGK-PVPQMRWTLNGTALTHST 1201
+ V V PP ++ ++ R+ ++ L C A+ P+ + W + ++ +
Sbjct: 2749 ARKDFLVRVTAPPHFEKEREEVVARVG--DTMLLTCNAESSVPLSSVYWHAHDESVQNGV 2806
Query: 1202 PGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPV-ISNGGTKQVI 1378
A++ + + N+ L D+G Y C A N AG + + V++ P + +I
Sbjct: 2807 ITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIETPYFLDQQKLYPII 2866
Query: 1379 EGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCS 1558
G+ ++C G P P + ++++G R+ + V + G L I + G Y C
Sbjct: 2867 LGKRLTLDCSATGTPPPTILFMKDGKRLNESDE-VDII--GSTLVIDNPQKEVEGRYTCI 2923
Query: 1559 ATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLN-GN 1735
A N+AG +++ +EVL+ PK+ V +G +L C + I+W+ G
Sbjct: 2924 AENKAGRSEKDMMVEVLLPPKLSKEWINVEV-QAGDPLTLECPIEDTSGVHITWSRQFGK 2982
Query: 1736 DIKDGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKISTSGN 1912
D + + L+I +A Y C A NDAG F V PKI
Sbjct: 2983 DGQLDMRAQSSSDKSKLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNTPPKIFGDSF 3042
Query: 1913 RYINGSEGTETVIKCXXXXXXXXXXX-XKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQG 2089
T I C +G P+L + + + ++I + + + +G
Sbjct: 3043 STTEIVADTTLEIPCRTEGIPPPEISWFLDGKPILEMPGVTYKQGDLSLRIDNIKPNQEG 3102
Query: 2090 EYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYK 2269
Y+C A NKAG A Q T + + P+++ V +G Q T+ CE G P+P + W K
Sbjct: 3103 RYTCVAENKAGRAEQDTYVEISEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLK 3162
Query: 2270 DNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVV 2449
D E T+ + +TK + + + G YTC A N ++ D+ V++PP +
Sbjct: 3163 DGEPYTSDLLQ--FSTKLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEVLVPPRIE 3220
Query: 2450 PERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDD 2629
E + T + C TG P P ++W R N ++ + L IRN D
Sbjct: 3221 DEERVLQGKEGNTYMVHCQVTGRPVPYVTWKR-------NGKEIEQFNPVLHIRNATRAD 3273
Query: 2630 DGFYHCIAKSDAGQKIA-------------TRKLIVNKPSDRPAPIWVECDEKGKPKKTE 2770
+G Y CIA ++AG +A T + N A I EC G PK T
Sbjct: 3274 EGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNIVEGESAKI--ECKIDGHPKPTI 3331
Query: 2771 YMIDRGDTP--DDNPQLLPWKDV--------EDSSLNGSIAYRCMPGPRSSRTVLLHAAP 2920
+ +G P DN L P D D L +A V ++ P
Sbjct: 3332 SWL-KGGRPFNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKP 3390
Query: 2921 QFIVKPKNTTAAI-GAIVELRCSAAGPPHPTITWAK-DGKLIEDSKFEIAYSH-LKVTLN 3091
T A+ G + L+C G P PT+TW + D + DS+ I ++ LK+
Sbjct: 3391 YIDETIDQTPKAVAGGEIILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNNYDLKINSV 3450
Query: 3092 STSDSGEYTCMAQNSVGSSTV---------SAFINVDNNILPTPKPSSNQKNVAVITCYE 3244
+T D+G+Y+C+A N G+ T F+ N+ + + + V +
Sbjct: 3451 TTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPL 3510
Query: 3245 RNQAYSRGLTWEYNGVPMPKNLAGIHFMN-NGSLVILDTSSLKEGDLELYTCKVRNRRRH 3421
+ ++ RG P L + ++ +GS + ++ + L +G Y C+ N
Sbjct: 3511 PSISWFRG--------DKPVYLYDRYSISPDGSHITINKAKLSDGG--KYICRASNEAG- 3559
Query: 3422 SIPHLTSAFEGVPEVKTIDKVEVNN---------GDSVVLDCEVTSDPLTTHVVWTKN-- 3568
TS + + ++ K++ +N ++ L+C ++ P V+WTKN
Sbjct: 3560 -----TSDIDLILKILVPPKIDKSNIIGNPLAIVARTIYLECPISGIP-QPDVIWTKNGM 3613
Query: 3569 DQKMLDDDAIYXXXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNV 3718
D M D I + D+G Y C A+N GKA D L+V
Sbjct: 3614 DINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDV 3663
Score = 362 bits (928), Expect = 6e-98
Identities = 330/1318 (25%), Positives = 547/1318 (41%), Gaps = 79/1318 (5%)
Frame = +2
Query: 2 ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH 181
I G P P + W KNG D+ D + + N I + D G Y+C N GK
Sbjct: 726 IRGKPHPKIRWFKNGKDLIKPDDYIKI--NEGQLHIMGAKDEDAGAYSCVGENMAGKDVQ 783
Query: 182 DFSLDVLSPPEF--DIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDG 355
+L V P H + I+R+ +TL C LA I ++ W K + L
Sbjct: 784 VANLSVGRVPTIIESPHTVRVNIERQ---VTLQC---LAVGIPPP--EIEWQKGNVLLAT 835
Query: 356 DLTDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDV 535
DG L I+ A +E+ G +TCIA N G+ S + + +
Sbjct: 836 LNNPRYTQLADG-NLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVSPVLGHVPP 894
Query: 536 QPQVAVNQPTIMRCAVT-GHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAG 712
+ Q+ Q + C V G P PSI W+K+ K V + I+I G +L++ + G
Sbjct: 895 EEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEG 954
Query: 713 KWSCVAENDAG----------VKELEMVLD-----VFTPPV-------VSVKSDNPIKAL 826
K++C+A + AG +K+ E V VF P + V+V +
Sbjct: 955 KYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLD 1014
Query: 827 GETITLFCNASGNPYPQLKWAKGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQA 1006
GE + C SG P P + W G I + ++ L + K+ G YTCQA
Sbjct: 1015 GEGFAIPCVVSGTPPPIITWYLDGRPITPNSRDFTVTADNT-LIVRKADKSYSGVYTCQA 1073
Query: 1007 LNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTA 1186
N+AG +E ++ ++ P I+ S + T+ C G P P + W L+
Sbjct: 1074 TNSAGDNEQKTTIRIMNTPMISPG--QSSFNMVVDDLFTIPCDVYGDPKPVITWLLDDKP 1131
Query: 1187 LTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGT 1366
T V ++ + I NV+ + +G +TC+A+N AG+D + V P I+
Sbjct: 1132 FTEG-----VVNEDGSLTIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAENQ 1186
Query: 1367 KQV-IEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSG 1543
+++ ++ + V+EC + P P W G ++++ + DG L + + ++G
Sbjct: 1187 EKIALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDG-ALVLQNVKLENTG 1245
Query: 1544 IYLCSATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWT 1723
+++C +N AG +YTL V PKII+ PGV+ G +PC G P+ I +W
Sbjct: 1246 VFVCQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWN 1305
Query: 1724 LNGNDIKDGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKIS 1900
NG D+K E ++ GTL I +A++ + Y C N+AG + V P I
Sbjct: 1306 KNGIDLKMDEKKFSVDNLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHVDVQEPPIIL 1365
Query: 1901 TSGNRYINGSEGTETVIKCXXXXX-XXXXXXXKNGVPLLPSNNLIFSEDYKLIKILSTRL 2077
S G +KC + G+ + E + I S +
Sbjct: 1366 PSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRGIAIGTDTKGYVVESDGTLVIQSASV 1425
Query: 2078 SDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERP--RTQVVHKGDQVTLWCEASGVPQP 2251
D Y+C A+N AG A + V +P I + + + + +L+C P P
Sbjct: 1426 EDATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLP 1485
Query: 2252 AITWY-KDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIV 2428
I+WY D L+ + +T+ K+K +F + + +GVY C A N + + V
Sbjct: 1486 QISWYLNDKPLIDDKTSWKTSDDKRKLHVFKA-KITDSGVYKCVARNAAGEGSKSFQVEV 1544
Query: 2429 MIPPEVVPE--RMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQIL---- 2590
++P + + V + V L C +G P P I+W+ D + ++ +KY+
Sbjct: 1545 IVPLNLDESKYKKKVFAKEGEEVTLGCPVSGFPVPQINWVVDGTV-VEPGKKYKGATLSN 1603
Query: 2591 -GTTLAIRNVLPDDDGFYHCIAKSDA---------------------------GQKIATR 2686
G TL +V +G YHC+A+S G+ I+
Sbjct: 1604 DGLTLHFDSVSVKQEGNYHCVAQSKGNILDIDVELSVLAVPIVGEDDNLEVFLGKDISLS 1663
Query: 2687 KLIVNKPSDRPAPIW-VECDEKGKPKKTEYMIDRGDTPDDNPQLLPWKDVEDSSLNGSIA 2863
+ + D+ +W + E +P D P D +L + D+ +
Sbjct: 1664 CDLQTESDDKTTFVWSINGSESDRP-------DNVQIPSDGHRLY----ITDAKPENNGK 1712
Query: 2864 YRCM---PGPRSSRTVLLHA-APQFIVKP---KNTTAAIGAIVELRCSAAGPPHPTITWA 3022
Y C ++ RT+ L P V+P N + L+C G P PT+ W
Sbjct: 1713 YMCRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWK 1772
Query: 3023 KDGKLIEDS-KFEIAYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPK 3199
DG ++ S F+ + S L++ T S + +C A+N G+++ FI N PT K
Sbjct: 1773 IDGNDVDKSWLFDESLSLLRIE-KLTGKSAQISCTAENKAGTASRDFFI--QNIAAPTFK 1829
Query: 3200 PSSNQKNV----AVITCYERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSL 3367
+Q+ + IT +TW G+P+ +N A I ++N L IL+ +
Sbjct: 1830 NEGDQETIFRESETITLDCPVSLGDFQITWMKQGLPLTENDA-IFTLDNTRLTILNANRD 1888
Query: 3368 KEGDLELYTCKVRNRRRHSIPHLTSAFEGVPEVK-TIDKVEVNNGDSVVLDCEVTSDPLT 3544
E ++YTC N + +P++K + +E+N G+ ++L C+ +P
Sbjct: 1889 HE---DIYTCVANNTAGQVSKDFDVVVQVLPKIKNAVVTLEINEGEEIILTCDAEGNPTP 1945
Query: 3545 THVVWTKNDQKMLDDDAIYXXXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNV 3718
T W N Q L +A++ KY GVYKC A+N +G+A ++V
Sbjct: 1946 T-AKWDFN-QGDLPKEAVFVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAVKTINVHV 2001
Score = 354 bits (909), Expect = 1e-95
Identities = 319/1287 (24%), Positives = 525/1287 (40%), Gaps = 58/1287 (4%)
Frame = +2
Query: 8 GIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDF 187
G P P + W K+G I D R + I + +DQGRYTC ATN G +
Sbjct: 2504 GSPSPTITWLKDGNAIEPND-RYVFFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLEN 2562
Query: 188 SLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTD 367
+L+V+ PP D + EG + L C D +DV W KD ++ D
Sbjct: 2563 TLEVIIPPVIDGERREAVAVIEGFSSELFC------DSNSTGVDVEWQKDGLTINQDTLR 2616
Query: 368 N---VDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQ 538
+ I G+K++ A ++G YTCI N AGEA F + PP I +
Sbjct: 2617 GDSFIQIPSSGKKMSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVNDPPSISDELSSAN 2676
Query: 539 PQVAVNQ-PTIMRCAVTGHPFPSIKWLKNGKEVTDDENI-RIVEQGQVLQILRTDSDHAG 712
Q V P + C V+G P P + WL + K + D + G+ L+I+R+ +HAG
Sbjct: 2677 IQTIVPYYPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIVRSQVEHAG 2736
Query: 713 KWSCVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGN-PYPQLKWA 889
++C A+N+ G + ++ V PP + + + +G+T+ L CNA + P + W
Sbjct: 2737 TYTCEAQNNVGKARKDFLVRVTAPPHFEKEREEVVARVGDTMLLTCNAESSVPLSSVYWH 2796
Query: 890 KGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEI 1069
+ + ++ + L++ +++ D G Y C A+N AG ++ + V+ P
Sbjct: 2797 AHDESVQNGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIETPYF 2856
Query: 1070 NRDGIDMSPRLPA--QQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQI 1243
+D P + LTL C A G P P + + +G L S + S + I
Sbjct: 2857 ----LDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDIIGST---LVI 2909
Query: 1244 NNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTK-QVIEGELAVIECLVEGY 1420
+N +G YTC AEN AG V+V+ P +S +V G+ +EC +E
Sbjct: 2910 DNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLECPIEDT 2969
Query: 1421 PAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTL 1600
++W R + + +D L I++A D+ Y C A N+AG A+ + +
Sbjct: 2970 SGVHITWSRQFGKDGQLDMRAQSSSDKSKLYIMQATPEDADSYSCIAVNDAGGAEAVFQV 3029
Query: 1601 EVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADG 1780
V PKI + + + +PC G P P ISW L+G I + D
Sbjct: 3030 TVNTPPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFLDGKPILEMPGVTYKQGDL 3089
Query: 1781 TLHIEKAE-ERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKC 1957
+L I+ + + Y C A+N AG + V+ P++ + + EG +T I+C
Sbjct: 3090 SLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEISEPPRV-VMASEVMRVVEGRQTTIRC 3148
Query: 1958 XXXXXXXXXXX-XKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQ 2134
K+G P S+ L FS + + T L+D G Y+C A NKAG +
Sbjct: 3149 EVFGNPEPVVNWLKDGEPYT-SDLLQFSTKLSYLHLRETTLADGGTYTCIATNKAGESQT 3207
Query: 2135 KTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETAT 2314
T++ V V P+I + R +G+ + C+ +G P P +TW ++ + +
Sbjct: 3208 TTDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEIEQFN------ 3261
Query: 2315 TKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVF 2494
+ + + + G Y+C A N + D + V P + ++
Sbjct: 3262 ---PVLHIRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNIVEGESAK 3318
Query: 2495 LSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQK 2674
+ C G P+P ISW++ +N G TL I D G Y C+A + G
Sbjct: 3319 IECKIDGHPKPTISWLKGGRPFNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDS 3378
Query: 2675 -------IATRKLIVNKPSDRP-----APIWVECDEKGKPKKTEYMIDRGD--TPDDNPQ 2812
+ T+ I P I ++C G P T RGD P+D+
Sbjct: 3379 EQDFKVNVYTKPYIDETIDQTPKAVAGGEIILKCPVLGNPTPTVTW-KRGDDAVPNDSRH 3437
Query: 2813 LLPWK-DVEDSSLNGSIA--YRCMPGPRSSRTVLLHAA-----PQFIVKPKNTTAAI-GA 2965
+ D++ +S+ A Y C+ + +AA P F+ K N I
Sbjct: 3438 TIVNNYDLKINSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIEND 3497
Query: 2966 IVELRCSAAGPPHPTITWAKDGK---LIEDSKFEIAYSHLKVTLNSTSDSGEYTCMAQNS 3136
+ + C P P+I+W + K L + SH+ + SD G+Y C A N
Sbjct: 3498 TITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAKLSDGGKYICRASNE 3557
Query: 3137 VGSSTVSAFINVDNNILPTPKPSSN--QKNVAVITCYERNQAYSRGLTWEYNGVPMPKNL 3310
G+S + + + ++P SN +A++ A + L +G+P P +
Sbjct: 3558 AGTSDIDLILKI---LVPPKIDKSNIIGNPLAIV-------ARTIYLECPISGIPQPDVI 3607
Query: 3311 ---AGIHFMNNGSLVILDTSSLKEG-------DLELYTCKVRNRRRHSIPHLTSAFEGVP 3460
G+ S VIL ++ G D YTC NR + + P
Sbjct: 3608 WTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPP 3667
Query: 3461 E--VKTIDKVEVNNGDSVVLDCEV-TSDPLTTHVV---WTKNDQKM---LDDDAIYXXXX 3613
E + GD++ L C + ++ + V+ WTK+ + + L D+
Sbjct: 3668 EFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDG 3727
Query: 3614 XXXXXXXXEKYDEGVYKCVASNSIGKA 3694
+ G+Y C+A N G+A
Sbjct: 3728 RKLTISQASLENAGLYTCIALNRAGEA 3754
Score = 339 bits (869), Expect = 4e-91
Identities = 342/1318 (25%), Positives = 545/1318 (40%), Gaps = 83/1318 (6%)
Frame = +2
Query: 14 PQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSL 193
P P + W N + + + + + ++TD G Y C A N G+ S F +
Sbjct: 1483 PLPQISWYLNDKPLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQV 1542
Query: 194 DVLSPPEFDIHGTQPTI-KREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALD-GDLTD 367
+V+ P D + + +EG+ +TL CP+ V ++W D ++ G
Sbjct: 1543 EVIVPLNLDESKYKKKVFAKEGEEVTLGCPVS-----GFPVPQINWVVDGTVVEPGKKYK 1597
Query: 368 NVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQV 547
+S+DG L S++ G Y C+A ++ ++ ++ +L+ P++ D +V
Sbjct: 1598 GATLSNDGLTLHFDSVSVKQEGNYHCVAQSKGNILDIDVELSVLAVPIVG---EDDNLEV 1654
Query: 548 AVNQPTIMRCAVT--GHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWS 721
+ + + C + + W NG E +N++I G L I ++ GK+
Sbjct: 1655 FLGKDISLSCDLQTESDDKTTFVWSINGSESDRPDNVQIPSDGHRLYITDAKPENNGKYM 1714
Query: 722 CVAENDAGVKELEMVLDVFTPPV-VSVKSDNPIKALGET-ITLFCNASGNPYPQLKWAKG 895
C N AG E + LDV PPV V + K +G I L C +GNP P + W
Sbjct: 1715 CRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKID 1774
Query: 896 G-----SLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVP 1060
G S +FD SL R++ K + +C A N AGT+ + +
Sbjct: 1775 GNDVDKSWLFDE------SLSLLRIEKLTGKSAQI---SCTAENKAGTASRDFFIQNIAA 1825
Query: 1061 PEINRDGIDMSPRLPAQQSLTLQCLAQGKPVP----QMRWTLNGTALTHSTPGITVASDS 1228
P +G D +++TL C PV Q+ W G LT + T+ D+
Sbjct: 1826 PTFKNEG-DQETIFRESETITLDC-----PVSLGDFQITWMKQGLPLTENDAIFTL--DN 1877
Query: 1229 TFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGG-TKQVIEGELAVIEC 1405
T + I N + + +YTC A N AG + ++V V P I N T ++ EGE ++ C
Sbjct: 1878 TRLTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQVLPKIKNAVVTLEINEGEEIILTC 1937
Query: 1406 LVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQ 1585
EG P P W + N+ + + V +V + + + +G+Y C ATN+ G A
Sbjct: 1938 DAEGNPTPTAKW--DFNQGDLPKEAV-FVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAV 1994
Query: 1586 QAYTLEVLVSPKIITS-TPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENG- 1759
+ + V P+ + T LT + +L C V ISWT+NG +G
Sbjct: 1995 KTINVHVRTKPRFESGLTESELTVNLTRSITLECDVDDAIGVGISWTVNGKPFLAETDGV 2054
Query: 1760 HTIGADGTLHIEKAE-ERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEG 1936
T+ LHI A+ + H Y CT N+AG T F + V P I G Y E
Sbjct: 2055 QTLAGGRFLHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQVPPTIVNEGGEY-TVIEN 2113
Query: 1937 TETVIKCXXXXXXXXXXX-XKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAAN 2113
V+ C K+G P+ ++ + + KI+ ++ +G Y C A N
Sbjct: 2114 NSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEGQQFKIVHAEIAHKGSYICMAKN 2173
Query: 2114 KAGNATQKTNLNVGVAPKIMERPRTQVVH-KGDQVTLWCEASGVP--QPAITWYKDNELL 2284
G A ++++ P I + + V KG + C + I W ++ + +
Sbjct: 2174 DVGTAEISFDVDIITRPMIQKGIKNIVTAIKGGALPFKCPIDDDKNFKGQIIWLRNYQPI 2233
Query: 2285 TNTGVDETAT--TKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVV--P 2452
D T + + + +++ + G Y+C+ +N D V++PP ++
Sbjct: 2234 DLEAEDARITRLSNDRRLTILNVTENDEGQYSCRVKNDAGENSFDFKATVLVPPTIIMLD 2293
Query: 2453 ERMNVSTNPRQTVFLSCNATGIPEPVISWMRDS------NIA--IQNNEKYQILGTTLAI 2608
+ N + TV LSC ATG PEP I+W +D NIA I N E + G L I
Sbjct: 2294 KDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGE---LNGNQLKI 2350
Query: 2609 RNVLPDDDGFYHCIAKSDAG---QKIATRKLIVNK------PSDRPA----------PIW 2731
+ D G Y C A + AG Q + + + K PSD + P++
Sbjct: 2351 TRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQNERVVISCPVY 2410
Query: 2732 VECDEK------GKPKKTEYMIDRGDTPDDNPQLLPWKDVE-DSSLNGSIAYRCMPGPRS 2890
K GKP +++ + T + +L +K E DSS IA +
Sbjct: 2411 ARPPAKITWLKAGKPLQSDKFVK---TSANGQKLYLFKLRETDSSKYTCIATNEAGTDKR 2467
Query: 2891 SRTVLLHAAPQF----IVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSK-- 3052
V + AP F IV+ T G L C A G P PTITW KDG IE +
Sbjct: 2468 DFKVSMLVAPSFDEPNIVR--RITVNSGNPSTLHCPAKGSPSPTITWLKDGNAIEPNDRY 2525
Query: 3053 -FEIAYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAV 3229
F A L+++ SD G YTC+A NSVGS + + V I+P ++ VAV
Sbjct: 2526 VFFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLENTLEV---IIPPVIDGERREAVAV 2582
Query: 3230 ITCYERN---QAYSRGLT--WEYNGVPMPKN-LAGIHFMN-NGSLVILDTSSLKEGDLEL 3388
I + + S G+ W+ +G+ + ++ L G F+ S + S ++ D
Sbjct: 2583 IEGFSSELFCDSNSTGVDVEWQKDGLTINQDTLRGDSFIQIPSSGKKMSFLSARKSDSGR 2642
Query: 3389 YTCKVRNRRRHSIPHLTSAFEGVPEVKTIDKVEVNNGDSVV------LDCEVTSDPLTTH 3550
YTC VRN + A P + D++ N ++V ++C V+ P
Sbjct: 2643 YTCIVRNPAGEARKLFDFAVNDPPSIS--DELSSANIQTIVPYYPVEINCVVSGSP-HPK 2699
Query: 3551 VVWTKNDQKMLDDDAIYXXXXXXXXXXXXEKYDE--GVYKCVASNSIGKAFDDTQLNV 3718
V W +D+ + D A Y E G Y C A N++GKA D + V
Sbjct: 2700 VYWLFDDKPLEPDSAAYELTNNGETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLVRV 2757
Score = 319 bits (817), Expect = 5e-85
Identities = 314/1317 (23%), Positives = 536/1317 (39%), Gaps = 84/1317 (6%)
Frame = +2
Query: 26 VIWTKNGMDINMTDSRVILAQNNET--FGIENVQVTDQGRYTCTATNRGGKASHDFSLDV 199
+ W K G DI + N +T + I + + D G Y C + G S ++
Sbjct: 460 IYWVKTGEDII---GGPLFYHNTDTSVWTIPELSLKDAGEYECRVISNNGNYSVKTRVET 516
Query: 200 L-SPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVD 376
SPPE I G + G+ L C + A ++ ++ WT+ + N +
Sbjct: 517 RESPPE--IFGVRNVSVPLGEAAFLHCSTRSAGEV-----EIRWTRYGATVFNG--PNTE 567
Query: 377 ISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVN 556
+ L I + +AG+Y C+A N G ++ + +++I+ PP + ++ DV +
Sbjct: 568 RNPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMRLDIMEPPSVKVTPQDVY--FNMR 625
Query: 557 QPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSCVAEN 736
+ + C G P P + W G+ + +D ++ + + L I G + C A +
Sbjct: 626 EGVNLSCEAMGDPKPEVHWYFKGRHLLNDYKYQVGQDSKFLYIRDATHHDEGTYECRAMS 685
Query: 737 DAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNA-SGNPYPQLKWAKGGSLIFD 913
AG L + TPP V + + + G+ ++ C G P+P+++W K G +
Sbjct: 686 QAGQARDTTDLMLATPPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIK 745
Query: 914 SPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDGIDMS 1093
D I + +L I K D G Y+C N AG ++ V P I +
Sbjct: 746 PDD--YIKINEGQLHIMGAKDEDAGAYSCVGENMAGKDVQVANLSVGRVPTIIES--PHT 801
Query: 1094 PRLPAQQSLTLQCLAQGKPVPQMRWTLNGTAL-THSTPGITVASDSTFIQINNVSLSDKG 1270
R+ ++ +TLQCLA G P P++ W L T + P T +D + I + + D+G
Sbjct: 802 VRVNIERQVTLQCLAVGIPPPEIEWQKGNVLLATLNNPRYTQLADGNLL-ITDAQIEDQG 860
Query: 1271 VYTCYAENVAG--SDNLMYNVDVVQAPVISN-GGTKQVIEGELAVIECLVE-GYPAPQVS 1438
+TC A N G S + V + +PV+ + +Q+IEG+ + C+V G P P +
Sbjct: 861 QFTCIARNTYGQQSQSTTLMVTGLVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIV 920
Query: 1439 WLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSP 1618
W+++ VE G ++ G +L + D G Y C A + AG++ ++++ P
Sbjct: 921 WIKDDKPVEEGPT-IKIEGGGSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKP 979
Query: 1619 KIITSTPG--VLTPS-------------------SGSKFSLPCAVRGYPDPIISWTLNGN 1735
+ + G V P+ G F++PC V G P PII+W L+G
Sbjct: 980 EFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEGFAIPCVVSGTPPPIITWYLDGR 1039
Query: 1736 DIKDGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKISTSGN 1912
I T+ AD TL + KA++ + +Y C A N AG + + ++ + P IS
Sbjct: 1040 PITPNSRDFTVTADNTLIVRKADKSYSGVYTCQATNSAGDNEQKTTIRIMNTPMISP--- 1096
Query: 1913 RYINGSEGTETVIKCXXXXXXXXXXXXKNGVPLL----PSNNLIFSEDYKLIKILSTRLS 2080
G V+ K + L P + +ED L I + +
Sbjct: 1097 ----GQSSFNMVVDDLFTIPCDVYGDPKPVITWLLDDKPFTEGVVNEDGSLT-IPNVNEA 1151
Query: 2081 DQGEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAIT 2260
+G ++C A N AGN T+ L V P I + ++ + D + L C A +P P
Sbjct: 1152 HRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAENQEKIALQNDDIVLECPAKALPPPVRL 1211
Query: 2261 WYKDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPP 2440
W + E + + + T + +++ ++ GV+ C+ N L V P
Sbjct: 1212 WTYEGEKIDSQLIPHTIR-EDGALVLQNVKLENTGVFVCQVSNLAGEDSLSYTLTVHEKP 1270
Query: 2441 EVVPERMNVSTNPRQ-TVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQI--LGTTLAIR 2611
+++ E V + T+ + C ATG+PE + +W ++ + +K+ + LGT L I
Sbjct: 1271 KIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVDNLGT-LRIY 1329
Query: 2612 NVLPDDDGFYHCIAKSDAGQKIATRKLIVNKP---------------SDRPAPIWVECDE 2746
+D G Y+C+ ++AG T + V +P DR + ++C
Sbjct: 1330 EADKNDIGNYNCVVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAVVGDR---VELKCYV 1386
Query: 2747 KGKPKKTEYMIDRG-----DTP-----DDNPQLLPWKDVEDSSLNGSIAYRCMPGPRSSR 2896
+ P + RG DT D ++ VED+++ A ++
Sbjct: 1387 EASPPASVTWFRRGIAIGTDTKGYVVESDGTLVIQSASVEDATIYTCKASNPAGKAEANL 1446
Query: 2897 TVLLHAAPQFIVKPKNTTAAIGAI--VELRCSAAGPPHPTITWAKDGKLIEDSKFEIAYS 3070
V + A+P T +I L C P P I+W + K + D K S
Sbjct: 1447 QVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTS 1506
Query: 3071 HLKVTLN----STSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITC 3238
K L+ +DSG Y C+A+N+ G + S + V I+P S K
Sbjct: 1507 DDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEV---IVPLNLDESKYKKKVFA-- 1561
Query: 3239 YERNQAYSRG----------LTWEYNG--VPMPKNLAGIHFMNNGSLVILDTSSLK-EGD 3379
+ + + G + W +G V K G N+G + D+ S+K EG+
Sbjct: 1562 -KEGEEVTLGCPVSGFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQEGN 1620
Query: 3380 LELYTCKVRNRRRHSIPHLTSAFEGVPEVKTIDKVEVNNGDSVVLDCEVT--SDPLTTHV 3553
Y C +++ + + VP V D +EV G + L C++ SD TT V
Sbjct: 1621 ---YHCVAQSKGNILDIDVELSVLAVPIVGEDDNLEVFLGKDISLSCDLQTESDDKTTFV 1677
Query: 3554 VWTKNDQKMLDDDAIYXXXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNVYE 3724
+ D+ + + G Y C +NS GKA L+V E
Sbjct: 1678 WSINGSESDRPDNVQIPSDGHRLYITDAKPENNGKYMCRVTNSAGKAERTLTLDVLE 1734
Score = 309 bits (792), Expect = 4e-82
Identities = 333/1324 (25%), Positives = 536/1324 (40%), Gaps = 97/1324 (7%)
Frame = +2
Query: 23 DVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVL 202
++ WT+ G + N T I +V D G Y C A N GG ++ LD++
Sbjct: 550 EIRWTRYGATV-FNGPNTERNPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMRLDIM 608
Query: 203 SPPEFDIHGTQPTIK-REGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDI 379
PP + REG + L+C E + D +V W R L D +
Sbjct: 609 EPPSVKVTPQDVYFNMREG--VNLSC-----EAMGDPKPEVHWYFKGRHLLNDY--KYQV 659
Query: 380 SDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQ 559
D + L I A+ + G Y C A+++AG+A + + +PP ++I +N + V
Sbjct: 660 GQDSKFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKM--MVGRGD 717
Query: 560 PTIMRC-AVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSCVAEN 736
C + G P P I+W KNGK++ ++ + +GQ L I+ + AG +SCV EN
Sbjct: 718 RVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQ-LHIMGAKDEDAGAYSCVGEN 776
Query: 737 DAGVKELEMVLDVFTPPVVSVKSDNPIKA-LGETITLFCNASGNPYPQLKWAKGGSLIFD 913
AG L V P + ++S + ++ + +TL C A G P P+++W KG L+
Sbjct: 777 MAGKDVQVANLSVGRVPTI-IESPHTVRVNIERQVTLQCLAVGIPPPEIEWQKGNVLLAT 835
Query: 914 SPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDV--LVPPEINRDGID 1087
+ L L I + D G +TC A N G S ++ V LV P + +
Sbjct: 836 LNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVSPVLGH--VP 893
Query: 1088 MSPRLPAQQSLTLQC-LAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLSD 1264
+L Q LTL C + G P P + W + + P I + + +++ + D
Sbjct: 894 PEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEG-PTIKIEGGGSLLRLRGGNPKD 952
Query: 1265 KGVYTCYAENVAGSDNLMYNVDVVQAP-----------------------VISNGGTKQV 1375
+G YTC A + AG+ L NV +++ P V T V
Sbjct: 953 EGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDV 1012
Query: 1376 IEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLC 1555
++GE I C+V G P P ++W +G + + VT L + +A SG+Y C
Sbjct: 1013 LDGEGFAIPCVVSGTPPPIITWYLDGRPITPNSRDFT-VTADNTLIVRKADKSYSGVYTC 1071
Query: 1556 SATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSS--GSKFSLPCAVRGYPDPIISWTLN 1729
ATN AG +Q T+ ++ +P I +PG + + F++PC V G P P+I+W L+
Sbjct: 1072 QATNSAGDNEQKTTIRIMNTPMI---SPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLD 1128
Query: 1730 GNDIKDGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKISTS 1906
+G + DG+L I E H + C A+N AG DT + P I+
Sbjct: 1129 DKPFTEG----VVNEDGSLTIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAE 1184
Query: 1907 GNRYINGSEGTETVIKCXXXX-----XXXXXXXXKNGVPLLPSNNLIFSEDYKLIKILST 2071
I + + V++C K L+P ED L+ + +
Sbjct: 1185 NQEKI-ALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHT---IREDGALV-LQNV 1239
Query: 2072 RLSDQGEYSCTAANKAGNATQKTNLNVGVAPKIM-ERPRTQVVHKGDQVTLWCEASGVPQ 2248
+L + G + C +N AG + L V PKI+ E P V KG + + C A+GVP+
Sbjct: 1240 KLENTGVFVCQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPE 1299
Query: 2249 PAITWYKDNELLTNTGVDETATTKKKSV-------IFSSISPSQAGVYTCKAENWVASTE 2407
TW K+ G+D KK SV I+ + + G Y C N +++
Sbjct: 1300 VIRTWNKN-------GIDLKMDEKKFSVDNLGTLRIYEA-DKNDIGNYNCVVTNEAGTSQ 1351
Query: 2408 EDIDLIVMIPPEVVPE-RMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQ 2584
+ V PP ++P + N + V L C P ++W R IAI + K
Sbjct: 1352 MTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFR-RGIAIGTDTKGY 1410
Query: 2585 ILGT--TLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVNKPSD--RPAPIWVECDEKG 2752
++ + TL I++ +D Y C A + AG+ A ++ V D P + E ++
Sbjct: 1411 VVESDGTLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESIKES 1470
Query: 2753 KPKKTEYMIDRGDTP------DDNPQL---LPWKDVED--------SSLNGSIAYRCM-- 2875
P + P +D P + WK +D + + S Y+C+
Sbjct: 1471 HPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVAR 1530
Query: 2876 ----PGPRSSRT-VLLHAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLI 3040
G +S + V++ K A G V L C +G P P I W DG ++
Sbjct: 1531 NAAGEGSKSFQVEVIVPLNLDESKYKKKVFAKEGEEVTLGCPVSGFPVPQINWVVDGTVV 1590
Query: 3041 EDSK--FEIAYSHLKVTLN----STSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKP 3202
E K S+ +TL+ S G Y C+AQ S I+V+ ++L P
Sbjct: 1591 EPGKKYKGATLSNDGLTLHFDSVSVKQEGNYHCVAQ----SKGNILDIDVELSVLAVPIV 1646
Query: 3203 SSNQ-------KNVAVITCYERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNG-SLVILDT 3358
+ K++++ + W NG + + ++G L I D
Sbjct: 1647 GEDDNLEVFLGKDISLSCDLQTESDDKTTFVWSINGSESDRP-DNVQIPSDGHRLYITDA 1705
Query: 3359 SSLKEGDLELYTCKVRN-----RRRHSIPHLTSAFEGVPEVKTIDKVEVNNGDSVVLDCE 3523
G Y C+V N R ++ L P + K+ NN ++L C+
Sbjct: 1706 KPENNGK---YMCRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLIGNN--PIILQCQ 1760
Query: 3524 VTSDPLTTHVVWTKN----DQKMLDDDAIYXXXXXXXXXXXXEKYDEGVYKCVASNSIGK 3691
VT +P T V+W + D+ L D+++ + C A N G
Sbjct: 1761 VTGNPKPT-VIWKIDGNDVDKSWLFDESLSLLRIEKLTGKSAQ------ISCTAENKAGT 1813
Query: 3692 AFDD 3703
A D
Sbjct: 1814 ASRD 1817
Score = 298 bits (764), Expect = 7e-79
Identities = 292/1171 (24%), Positives = 480/1171 (40%), Gaps = 71/1171 (6%)
Frame = +2
Query: 542 QVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWS 721
Q V + + C V +I W+K G+++ V I AG++
Sbjct: 439 QEFVGRDLNLSCTVESASAYTIYWVKTGEDIIGGPLFYHNTDTSVWTIPELSLKDAGEYE 498
Query: 722 CVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGS 901
C ++ G ++ ++ P N LGE L C+ +++W + G+
Sbjct: 499 CRVISNNGNYSVKTRVETRESPPEIFGVRNVSVPLGEAAFLHCSTRSAGEVEIRWTRYGA 558
Query: 902 LIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDG 1081
+F+ P+ R G L I H+ + D G Y C A NA G S + +D++ PP +
Sbjct: 559 TVFNGPNTERNPTNGT-LKIHHVTRADAGVYECMARNAGGMSTRKMRLDIMEPPSVKVTP 617
Query: 1082 IDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLS 1261
D+ + ++ + L C A G P P++ W G L + V DS F+ I + +
Sbjct: 618 QDVYFNM--REGVNLSCEAMGDPKPEVHWYFKGRHLLNDYK-YQVGQDSKFLYIRDATHH 674
Query: 1262 DKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVI-EGELAVIEC-LVEGYPAPQV 1435
D+G Y C A + AG ++ + P + K ++ G+ EC + G P P++
Sbjct: 675 DEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKI 734
Query: 1436 SWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVS 1615
W +NG + ++ + +G+ L I+ A+ D+G Y C N AG Q L V
Sbjct: 735 RWFKNGKDLIKPDDYIK-INEGQ-LHIMGAKDEDAGAYSCVGENMAGKDVQVANLSVGRV 792
Query: 1616 PKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENG--HTIGADGTLH 1789
P II S P + + + +L C G P P I W GN + N +T ADG L
Sbjct: 793 PTIIES-PHTVRVNIERQVTLQCLAVGIPPPEIEWQ-KGNVLLATLNNPRYTQLADGNLL 850
Query: 1790 IEKAE-ERHLIYECTAKNDAG--ADTLEFPVQTIVAPKIS--TSGNRYINGSEGTETVIK 1954
I A+ E + C A+N G + + V +V+P + + I G + T + +
Sbjct: 851 ITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVSPVLGHVPPEEQLIEGQDLTLSCV- 909
Query: 1955 CXXXXXXXXXXXXKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQ 2134
K+ P+ + L+++ D+G+Y+C A + AGN+T
Sbjct: 910 VVLGTPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEGKYTCIAVSPAGNSTL 969
Query: 2135 KTNLNVGVAPKIMERPRTQVVHK----------------------GDQVTLWCEASGVPQ 2248
N+ + P+ + +P +V K G+ + C SG P
Sbjct: 970 HINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEGFAIPCVVSGTPP 1029
Query: 2249 PAITWYKDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIV 2428
P ITWY D +T D T T ++I S +GVYTC+A N E+ + +
Sbjct: 1030 PIITWYLDGRPITPNSRDFTVTADN-TLIVRKADKSYSGVYTCQATNSAGDNEQKTTIRI 1088
Query: 2429 MIPPEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQN--NEKYQILGTTL 2602
M P + P + + + + C+ G P+PVI+W+ D + NE +L
Sbjct: 1089 MNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLDDKPFTEGVVNE-----DGSL 1143
Query: 2603 AIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVN-----------KPSDRPAPIWVECDEK 2749
I NV G + C A++ AG T L V+ K + + I +EC K
Sbjct: 1144 TIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAENQEKIALQNDDIVLECPAK 1203
Query: 2750 GKPKKTEYMIDRGDTPDDNPQLLPWKDVEDSS-------LNGSIAYRC----MPGPRS-S 2893
P G+ D QL+P ED + L + + C + G S S
Sbjct: 1204 ALPPPVRLWTYEGEKIDS--QLIPHTIREDGALVLQNVKLENTGVFVCQVSNLAGEDSLS 1261
Query: 2894 RTVLLHAAPQFIVK-PKNTTAAIGAIVELRCSAAGPPHPTITWAKDG--KLIEDSKFEI- 3061
T+ +H P+ I + P G +E+ C A G P TW K+G +++ KF +
Sbjct: 1262 YTLTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVD 1321
Query: 3062 AYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVI--- 3232
L++ +D G Y C+ N G+S ++ ++V P PS+ N AV+
Sbjct: 1322 NLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHVDVQEP--PIILPSTQTNNTAVVGDR 1379
Query: 3233 ---TCYERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKV 3403
CY + +TW G+ + + G ++G+LVI S D +YTCK
Sbjct: 1380 VELKCYV-EASPPASVTWFRRGIAIGTDTKGYVVESDGTLVI---QSASVEDATIYTCKA 1435
Query: 3404 RNRRRHSIPHLTSAFEGVPEVKTIDKV---EVNNGDSVVLDCEVTSDPLTTHVVWTKNDQ 3574
N + +L P++K D V + L C V S+PL + W ND+
Sbjct: 1436 SNPAGKAEANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPL-PQISWYLNDK 1494
Query: 3575 KMLDDDAIYXXXXXXXXXXXXEK--YDEGVYKCVASNSIGKAFDDTQLNVYEGDFLPLTG 3748
++DD + + D GVYKCVA N+ G+ Q+ V +PL
Sbjct: 1495 PLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEV----IVPL-- 1548
Query: 3749 FEGSGINIDDSSNAGGSSRREAYKKENEDAS 3841
N+D+S +++ + KE E+ +
Sbjct: 1549 ------NLDES-----KYKKKVFAKEGEEVT 1568
Score = 265 bits (678), Expect = 6e-69
Identities = 294/1175 (25%), Positives = 469/1175 (39%), Gaps = 79/1175 (6%)
Frame = +2
Query: 254 GDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGD--LTDNVDISDDGRKLTISQASLEN 427
G + L+C ++ A + W K + G N D S TI + SL++
Sbjct: 443 GRDLNLSCTVESAS-----AYTIYWVKTGEDIIGGPLFYHNTDTS----VWTIPELSLKD 493
Query: 428 AGLYTCIALNRAGEASLEFKVEIL-SPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPS 604
AG Y C ++ G S++ +VE SPP I RN V + + + C+
Sbjct: 494 AGEYECRVISNNGNYSVKTRVETRESPPEIFGVRN---VSVPLGEAAFLHCSTRSAGEVE 550
Query: 605 IKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTP 784
I+W + G V + N L+I AG + C+A N G+ +M LD+ P
Sbjct: 551 IRWTRYGATVFNGPNTERNPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMRLDIMEP 610
Query: 785 PVVSVKSDNPIKALGETITLFCNASGNPYPQLKW-AKGGSLIFDSPDGARISLKGARLDI 961
P V V + + E + L C A G+P P++ W KG L+ D ++ L I
Sbjct: 611 PSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLLNDYK--YQVGQDSKFLYI 668
Query: 962 PHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQC-LA 1138
D G Y C+A++ AG + + + + PP++ + I + ++ +C
Sbjct: 669 RDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKV--EIIQNKMMVGRGDRVSFECKTI 726
Query: 1139 QGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLM 1318
+GKP P++RW NG L P + + + I D G Y+C EN+AG D +
Sbjct: 727 RGKPHPKIRWFKNGKDLI--KPDDYIKINEGQLHIMGAKDEDAGAYSCVGENMAGKDVQV 784
Query: 1319 YNVDVVQAP-VISNGGTKQVIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRY-- 1489
N+ V + P +I + T +V ++CL G P P++ W + GN + + RY
Sbjct: 785 ANLSVGRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEW-QKGNVLLATLNNPRYTQ 843
Query: 1490 VTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEV--LVSPKIITSTPGVLTPSSG 1663
+ DG +L I +A+ D G + C A N G Q+ TL V LVSP ++ P G
Sbjct: 844 LADGNLL-ITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVSP-VLGHVPPEEQLIEG 901
Query: 1664 SKFSLPC-AVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKAEER-HLIYECTAK 1837
+L C V G P P I W + +++G G L + + Y C A
Sbjct: 902 QDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEGKYTCIAV 961
Query: 1838 NDAGADTLEFPVQTIVAPK--------------ISTSGNRYINGSEGTETV-------IK 1954
+ AG TL VQ I P+ IS +++ T V I
Sbjct: 962 SPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEGFAIP 1021
Query: 1955 CXXXXX-XXXXXXXKNGVPLLP-SNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNA 2128
C +G P+ P S + + D LI + S G Y+C A N AG+
Sbjct: 1022 CVVSGTPPPIITWYLDGRPITPNSRDFTVTADNTLI-VRKADKSYSGVYTCQATNSAGDN 1080
Query: 2129 TQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDET 2308
QKT + + P I + + D T+ C+ G P+P ITW D++ T V+E
Sbjct: 1081 EQKTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLDDKPFTEGVVNED 1140
Query: 2309 ATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQT 2488
S+ +++ + G +TC A+N + + L V P + E
Sbjct: 1141 G-----SLTIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAENQEKIALQNDD 1195
Query: 2489 VFLSCNATGIPEPVISWMRDSNIAIQNNEKYQIL-GTTLAIRNVLPDDDGFYHCIAKSDA 2665
+ L C A +P PV W + + I L ++NV ++ G + C + A
Sbjct: 1196 IVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDGALVLQNVKLENTGVFVCQVSNLA 1255
Query: 2666 GQKIATRKLIVN-KP---SDRPA--------PIWVECDEKGKPKKTEYMIDRG-----DT 2794
G+ + L V+ KP S+ P I + C G P+ G D
Sbjct: 1256 GEDSLSYTLTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDE 1315
Query: 2795 PDDNPQLLPWKDVEDSSLNGSIAYRCM---PGPRSSRTVLLHAAPQFIVKPK---NTTAA 2956
+ L + ++ N Y C+ S T + I+ P N TA
Sbjct: 1316 KKFSVDNLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAV 1375
Query: 2957 IGAIVELRCSAAGPPHPTITWAKDGKLI-EDSKFEIAYSHLKVTLNSTS--DSGEYTCMA 3127
+G VEL+C P ++TW + G I D+K + S + + S S D+ YTC A
Sbjct: 1376 VGDRVELKCYVEASPPASVTWFRRGIAIGTDTKGYVVESDGTLVIQSASVEDATIYTCKA 1435
Query: 3128 QNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITCYERNQAYSRGLTWEYNGVPMPKN 3307
N G + + N+ T S + K+ V+T +++ L P+P+
Sbjct: 1436 SNPAGKA--------EANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQ- 1486
Query: 3308 LAGIHFMNNGSLVILDTSSLKEGD----LELYTCKVRNRRRHSIPHLTSAFEG------- 3454
I + N +I D +S K D L ++ K+ + + +A EG
Sbjct: 1487 ---ISWYLNDKPLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVE 1543
Query: 3455 ------VPEVKTIDKVEVNNGDSVVLDCEVTSDPL 3541
+ E K KV G+ V L C V+ P+
Sbjct: 1544 VIVPLNLDESKYKKKVFAKEGEEVTLGCPVSGFPV 1578
>gi|39596105|emb|CAE69741.1| Hypothetical protein CBG16014
[Caenorhabditis briggsae]
Length = 2590
Score = 2310 bits (5986), Expect = 0.0
Identities = 1113/1436 (77%), Positives = 1238/1436 (85%), Gaps = 1/1436 (0%)
Frame = +2
Query: 500 SPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVL 679
+PP+ID +RN+ QPQVAVNQPTI+RC VTGHPFP+IKWLKNG EVT DENIRIVEQGQ L
Sbjct: 1159 APPIIDTTRNEAQPQVAVNQPTILRCPVTGHPFPTIKWLKNGVEVTSDENIRIVEQGQTL 1218
Query: 680 QILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNAS 859
QIL TDS HAGKWSCVAENDAGVKELEM+LDVFTPP VSV S+NPIKA+GETITLFCNA+
Sbjct: 1219 QILLTDSAHAGKWSCVAENDAGVKELEMLLDVFTPPKVSVHSENPIKAVGETITLFCNAT 1278
Query: 860 GNPYPQLKWAKGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASV 1039
GNP PQ+KW KGG++IFDSPDG R+SLKGARLDIPHLKK DVGDYTCQA+NAAGTSE S+
Sbjct: 1279 GNPPPQMKWLKGGAMIFDSPDGPRVSLKGARLDIPHLKKHDVGDYTCQAMNAAGTSEGSI 1338
Query: 1040 SVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVA 1219
SVDVLVPPEINRDGIDMSPRLPA Q LTL CLAQGKP P+++WTLNGT L S IT+
Sbjct: 1339 SVDVLVPPEINRDGIDMSPRLPASQILTLHCLAQGKPPPKIKWTLNGTELKASKE-ITIG 1397
Query: 1220 SDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVIEGELAVI 1399
+D++FIQINNVSLSDKGVY C+AEN AGSD+LMYNVDVVQAPVISNGGT+QVIEGELAVI
Sbjct: 1398 TDASFIQINNVSLSDKGVYECHAENSAGSDSLMYNVDVVQAPVISNGGTEQVIEGELAVI 1457
Query: 1400 ECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGS 1579
ECLVEGYPAPQVSWLRNGNRVETGVQGVRY+ +GR LTIIEARSLDSGIYLCSATNEAGS
Sbjct: 1458 ECLVEGYPAPQVSWLRNGNRVETGVQGVRYMAEGRKLTIIEARSLDSGIYLCSATNEAGS 1517
Query: 1580 AQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENG 1759
AQQAYTLEVLV PKI++ P LTPSS + FS+PCAVRGYP+PIISWT+NG +I +G G
Sbjct: 1518 AQQAYTLEVLVFPKIVSVAPETLTPSSNAGFSMPCAVRGYPEPIISWTVNGKNIFNGTMG 1577
Query: 1760 HTIGADGTLHIEKAEERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGT 1939
+ I +DGTLH+EKAE+R + +ECTAKNDAG D LE+ V TI+APKI +SG R +NGSEG
Sbjct: 1578 YKIDSDGTLHVEKAEQRTMTFECTAKNDAGLDHLEYKVHTIIAPKIGSSGVRSLNGSEGE 1637
Query: 1940 ETVIKCXXXXXXXXXXXXKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKA 2119
+T IKC KNG PLLPSN + F E + I STRLSDQGEYSCT ANKA
Sbjct: 1638 QTRIKCDIEADQSEITWTKNGAPLLPSNTIEFQEKKTFVVITSTRLSDQGEYSCTVANKA 1697
Query: 2120 GNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGV 2299
GNATQ T+LNVGVAPKI+ERP TQVVHKG+QVTLWCEASGVPQP+I+WYKD +LL+NTG+
Sbjct: 1698 GNATQVTSLNVGVAPKILERPSTQVVHKGEQVTLWCEASGVPQPSISWYKDEQLLSNTGI 1757
Query: 2300 DETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNP 2479
DETATTKKKSVIFSSI+PSQAGVYTCKAENWV +TEED+DLIVMI PEV PERMNVSTNP
Sbjct: 1758 DETATTKKKSVIFSSITPSQAGVYTCKAENWVGATEEDVDLIVMISPEVSPERMNVSTNP 1817
Query: 2480 RQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKS 2659
RQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFY+CIAKS
Sbjct: 1818 RQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYYCIAKS 1877
Query: 2660 DAGQKIATRKLIVNKPSDRPAPIWVECDEKGKPKKTEYMIDRGDTPDDNPQLLPWKDVED 2839
DAGQKIATRKLIVNKPSDRPAPIWVECDEKGKPKKTEYMIDRGDTPDDNPQLLPWKDVED
Sbjct: 1878 DAGQKIATRKLIVNKPSDRPAPIWVECDEKGKPKKTEYMIDRGDTPDDNPQLLPWKDVED 1937
Query: 2840 SSLNGSIAYRCMPGPRSSRTVLLHAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITW 3019
SSLNGSIAYRCMPGPRSSRTVLLHAAPQFIVKPKNTTAA+ A++ELRCSAAGPP+P ITW
Sbjct: 1938 SSLNGSIAYRCMPGPRSSRTVLLHAAPQFIVKPKNTTAAVRAVIELRCSAAGPPNPVITW 1997
Query: 3020 AKDGKLIEDSKFEIAYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPK 3199
AKDGKLIE+ K EIAYSHLK+ LNSTSDSGEY+C+AQNSVG+STVSAF+NVDN +LPTP
Sbjct: 1998 AKDGKLIENDKTEIAYSHLKLELNSTSDSGEYSCLAQNSVGTSTVSAFVNVDNIVLPTPI 2057
Query: 3200 PSSNQKNVAVITCYERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGD 3379
P + +KNVA+ITCYE+NQAYSRG+TWEYNG+PMPKNLAGIHFMNNGSLVILDTSSLKEGD
Sbjct: 2058 PMNVKKNVAIITCYEKNQAYSRGVTWEYNGIPMPKNLAGIHFMNNGSLVILDTSSLKEGD 2117
Query: 3380 LELYTCKVRNRRRHSIPHLTSAFEGVPEVKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVW 3559
L+LYTCKVRNRRRHSIPHL S +E VP VKT+D+VEVNNGDS V+DCEV+SDPLTTHVVW
Sbjct: 2118 LDLYTCKVRNRRRHSIPHLKSVYEEVPSVKTVDRVEVNNGDSTVIDCEVSSDPLTTHVVW 2177
Query: 3560 TKNDQKMLDDDAIYXXXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNVYEGDFLP 3739
TKNDQKM+DD+AIY EKYDEGVYKCVASNSIGKAFDDT+L VY+G+ P
Sbjct: 2178 TKNDQKMMDDEAIYVLPNNSLVLLDVEKYDEGVYKCVASNSIGKAFDDTKLTVYDGEITP 2237
Query: 3740 LTGFEGSGINIDDSSNAGGSSRREAYKKENEDASXXXXXXXXXXXXXXXXXXXXXXXXXX 3919
LTG EGSG+ I + SN G +RR+ +D
Sbjct: 2238 LTGSEGSGVEIAEPSNVGVPTRRDT---SVDDEEREKQLQMTTTTTTAPDVHTTQPSRVL 2294
Query: 3920 XXXXAKQYPTDDYHEGSANDDGFGPTTQDSLFEFNPPLHPEISVVNT-DCAGTINENGDC 4096
A ++PT+D ++GSAN FGPTT D L E LH + +VV+T DC GTINENGDC
Sbjct: 2295 TIKSAPEFPTEDMYDGSANYPEFGPTTHDVLIERQSDLHSQHAVVDTPDCYGTINENGDC 2354
Query: 4097 VDKDGKTHNLKILTGENHCPEGFAMNPHTRICEDLDECAFYQPCDFECINYDGGFQCNCP 4276
VD DG H LKIL+GEN CPEG+A+NP T +CEDLDEC F+ PCDFECIN +G ++C CP
Sbjct: 2355 VDGDGTHHRLKILSGENKCPEGYAINPRTNVCEDLDECQFHLPCDFECINTEGSYECRCP 2414
Query: 4277 LGYELAEEGCRDVNECESVRCEDGKACFNQLGGYECIDDPCPANYSLVDDRYCEPECENC 4456
GYELA++GC D+NECESVRCE+G+ACFNQLGGYECI+DPCPANY+LVDDRYCEP CENC
Sbjct: 2415 PGYELADDGCYDINECESVRCEEGRACFNQLGGYECIEDPCPANYTLVDDRYCEPLCENC 2474
Query: 4457 TSTPIQVHMLAIPSGLPISHIATLTAYDKSGRVLNDTTYAISDTGAPLARGRMTSGPFTI 4636
T TPIQVHMLAIPSGLP+SHIATLTAYDKSG+VLNDTTY+ISD P+ RGRM+SGPF I
Sbjct: 2475 TLTPIQVHMLAIPSGLPVSHIATLTAYDKSGKVLNDTTYSISDREGPMGRGRMSSGPFNI 2534
Query: 4637 KAVKRGHAQVWTNRVLAAGDHHKVRVRAHSDHATNELHAPKETNFLVLINVGQYPF 4804
+ VK GHAQVWTNR+LAAGDH KVRVRAHSDHATNELHAPKET FL+LINVGQYPF
Sbjct: 2535 REVKAGHAQVWTNRILAAGDHRKVRVRAHSDHATNELHAPKETLFLILINVGQYPF 2590
Score = 322 bits (826), Expect = 4e-86
Identities = 256/869 (29%), Positives = 375/869 (42%), Gaps = 23/869 (2%)
Frame = +2
Query: 134 GRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQV 313
GRYTC A N+ G++ D ++V PP+ Q EG T+TL CPI + +
Sbjct: 127 GRYTCIAENKAGRSEKDMIVEVQVPPKMK-QANQTFDVEEGGTLTLECPI----ENPNGA 181
Query: 314 MDVSWTKDSRALDGDLTDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVE 493
+ W D A+ + IS DG KL I QA +A YTC A N AG+ S F V
Sbjct: 182 RVIYWYTD--AIGKVDPNRSQISGDGTKLFIIQAQESDADRYTCRAHNEAGQDSSVFTVN 239
Query: 494 ILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDD-ENIRIVEQG 670
+L PP I ++ N + C TG P P I WL +GK + N+R +
Sbjct: 240 LLKPPTIP-GEAFSTTEIVSNTTMELNCQPTGKPDPEITWLLDGKPILPGMANVRFEDNN 298
Query: 671 QVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFC 850
+ L I G+++C A+N G E + +++ PP V + SD G T+ C
Sbjct: 299 KKLFIDYIKPSQEGRYTCRADNQLGRAEQDTYVEISEPPRVVMASDKMRVVEGRQTTIRC 358
Query: 851 NASGNPYPQLKWAKGGSLIFDSPDGARISLKGARLDIPHLKKT---DVGDYTCQALNAAG 1021
G P P++ W K G P + + RL HL++ D G YTC N AG
Sbjct: 359 EVFGEPEPKVSWLKDG-----EPYTSDLLQHSTRLSYLHLREATLQDGGKYTCIGTNKAG 413
Query: 1022 TSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHST 1201
+ + V++LV P I + D + + + C A G P P + W NG L
Sbjct: 414 EARTTTEVEILVAPTIEDE--DRVIYGKEGKPVQINCKASGTPYPTITWKKNGKELDEHN 471
Query: 1202 PGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVI-SNGGTKQVI 1378
+T I+N + D G Y+C A N AGS + +DV P T +I
Sbjct: 472 SVLT---------ISNATREDDGKYSCLATNEAGSAVADFLLDVYTRPSFHPETTTFNII 522
Query: 1379 EGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCS 1558
EG A IEC V+G+P P ++WL+ G + + V G L I++++ +D+G+Y C
Sbjct: 523 EGHNAKIECKVDGHPKPTITWLKAGRSL--NMNNVILSPRGDTLMILKSKRVDAGLYTCV 580
Query: 1559 ATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGND 1738
A N G+ +Q + + V P I + +G K L C V G P P + W +D
Sbjct: 581 AENTFGANEQDFKVNVFTKPYIDEAIDQTPKAVAGEKIDLKCPVLGNPTPTVYWKKGDDD 640
Query: 1739 -IKDGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKISTSGN 1912
I DG++ IG L I+ E+ Y C A NDAG + V I P G
Sbjct: 641 IIIDGKHYELIG--DVLRIKTVTEKDTGAYTCVAINDAGQLRTNYAVDVIGKPTFDRKGE 698
Query: 1913 RYINGSEGTETVIKCXXXXXXXXXXXXKNG-VPLLPSNNLIFSEDYKLIKILSTRLSDQG 2089
E + + C G L + SED I I S RLSD G
Sbjct: 699 NIYEVIEDHDITMDCGVTSRPLPNIAWYRGDNALYIQPHYTISEDGSQITINSARLSDGG 758
Query: 2090 EYSCTAANKAGNATQKTNLNVGVAPK-----IMERPRTQVVHKGDQVTLWCEASGVPQPA 2254
+Y+C A+N+AG++ + L + V P+ I+ P V + L C +G+PQP
Sbjct: 759 KYTCRASNEAGSSDIEVILRILVPPRIDKSNIIGNPLAIVAR---NIYLECPVTGIPQPE 815
Query: 2255 ITWYKDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMI 2434
+ W KD + T ++ + + AG YTC A N D +L V+
Sbjct: 816 VYWTKDGRDINATDSRIIYAQNNETFGIEKVQVTDAGRYTCTAVNRGGRIAHDFNLDVLS 875
Query: 2435 PPEVVPERMNVSTNPR-QTVFLSC---NATGIPEPV--ISWMRDSNIAIQNNEKYQIL-- 2590
PP R + T+ L+C A + + V +SW +DS +A+ E +
Sbjct: 876 PPSFDLYRTQPTIKREGDTITLTCPIKTAEDVADQVMDVSWTKDS-VALDGVETDNVHIS 934
Query: 2591 --GTTLAIRNVLPDDDGFYHCIAKSDAGQ 2671
G L I + G Y CIA + AG+
Sbjct: 935 DDGRKLTIDKASLVNAGMYTCIALNRAGE 963
Score = 322 bits (824), Expect = 7e-86
Identities = 290/1112 (26%), Positives = 465/1112 (41%), Gaps = 49/1112 (4%)
Frame = +2
Query: 2 ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH 181
++G P P + W KNG+++ +D + + + +T I G+++C A N G
Sbjct: 1186 VTGHPFPTIKWLKNGVEVT-SDENIRIVEQGQTLQILLTDSAHAGKWSCVAENDAGVKEL 1244
Query: 182 DFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDL 361
+ LDV +PP+ +H P IK G+TITL C + + W K A+ D
Sbjct: 1245 EMLLDVFTPPKVSVHSENP-IKAVGETITLFC-----NATGNPPPQMKWLKGG-AMIFDS 1297
Query: 362 TDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQP 541
D +S G +L I + G YTC A+N AG + V++L PP I+ D+ P
Sbjct: 1298 PDGPRVSLKGARLDIPHLKKHDVGDYTCQAMNAAGTSEGSISVDVLVPPEINRDGIDMSP 1357
Query: 542 QVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWS 721
++ +Q + C G P P IKW NG E+ + I I +QI G +
Sbjct: 1358 RLPASQILTLHCLAQGKPPPKIKWTLNGTELKASKEITIGTDASFIQINNVSLSDKGVYE 1417
Query: 722 CVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGS 901
C AEN AG L +DV PV+S + GE + C G P PQ+ W + G+
Sbjct: 1418 CHAENSAGSDSLMYNVDVVQAPVISNGGTEQV-IEGELAVIECLVEGYPAPQVSWLRNGN 1476
Query: 902 LIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDG 1081
+ G R +G +L I + D G Y C A N AG+++ + +++VLV P+I
Sbjct: 1477 RVETGVQGVRYMAEGRKLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVFPKI---- 1532
Query: 1082 IDMSPRLPAQQS---LTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNV 1252
+ ++P S ++ C +G P P + WT+NG + + T G + SD T +V
Sbjct: 1533 VSVAPETLTPSSNAGFSMPCAVRGYPEPIISWTVNGKNIFNGTMGYKIDSDGTL----HV 1588
Query: 1253 SLSDKGVYT--CYAENVAGSDNLMYNVDVVQAPVISNGGTKQV--IEGELAVIECLVEGY 1420
+++ T C A+N AG D+L Y V + AP I + G + + EGE I+C +E
Sbjct: 1589 EKAEQRTMTFECTAKNDAGLDHLEYKVHTIIAPKIGSSGVRSLNGSEGEQTRIKCDIEA- 1647
Query: 1421 PAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTL 1600
+++W +NG + + + + I R D G Y C+ N+AG+A Q +L
Sbjct: 1648 DQSEITWTKNGAPLLPS-NTIEFQEKKTFVVITSTRLSDQGEYSCTVANKAGNATQVTSL 1706
Query: 1601 EVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADG 1780
V V+PKI+ P G + +L C G P P ISW KD + G D
Sbjct: 1707 NVGVAPKIL-ERPSTQVVHKGEQVTLWCEASGVPQPSISW------YKDEQLLSNTGIDE 1759
Query: 1781 TLHIEK--------AEERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEG 1936
T +K + +Y C A+N GA + + +++P++S ++ +
Sbjct: 1760 TATTKKKSVIFSSITPSQAGVYTCKAENWVGATEEDVDLIVMISPEVSPE-RMNVSTNPR 1818
Query: 1937 TETVIKCXXXXXXXXXXXXKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANK 2116
+ C + NN + + I + D G Y C A +
Sbjct: 1819 QTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYYCIAKSD 1878
Query: 2117 AGN--ATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTN 2290
AG AT+K +N K +RP +W E +P T Y + +
Sbjct: 1879 AGQKIATRKLIVN-----KPSDRP----------APIWVECDEKGKPKKTEYMIDR--GD 1921
Query: 2291 TGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVS 2470
T D K V SS++ S A Y C + +++ P+ + + N +
Sbjct: 1922 TPDDNPQLLPWKDVEDSSLNGSIA--YRC-----MPGPRSSRTVLLHAAPQFIVKPKNTT 1974
Query: 2471 TNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCI 2650
R + L C+A G P PVI+W +D + N+K +I + L + D G Y C+
Sbjct: 1975 AAVRAVIELRCSAAGPPNPVITWAKDGKLI--ENDKTEIAYSHLKLELNSTSDSGEYSCL 2032
Query: 2651 AKSDAGQKIATRKLIV-NKPSDRPAPIWVE-------CDEKGKPKKTEYMIDRGDTPDDN 2806
A++ G + + V N P P+ V+ C EK + RG T + N
Sbjct: 2033 AQNSVGTSTVSAFVNVDNIVLPTPIPMNVKKNVAIITCYEKNQ------AYSRGVTWEYN 2086
Query: 2807 PQLLPWKDVEDSSL--NGSIA--------------YRCMPGPRSSRTVLLHAAPQFIVKP 2938
+P K++ NGS+ Y C R ++ + V
Sbjct: 2087 GIPMP-KNLAGIHFMNNGSLVILDTSSLKEGDLDLYTCKVRNRRRHSIPHLKSVYEEVPS 2145
Query: 2939 KNTTAAI----GAIVELRCSAAGPPHPT-ITWAK-DGKLIEDSKFEIAYSHLKVTLN-ST 3097
T + G + C + P T + W K D K+++D + ++ V L+
Sbjct: 2146 VKTVDRVEVNNGDSTVIDCEVSSDPLTTHVVWTKNDQKMMDDEAIYVLPNNSLVLLDVEK 2205
Query: 3098 SDSGEYTCMAQNSVGSSTVSAFINV-DNNILP 3190
D G Y C+A NS+G + + V D I P
Sbjct: 2206 YDEGVYKCVASNSIGKAFDDTKLTVYDGEITP 2237
Score = 290 bits (741), Expect = 3e-76
Identities = 216/731 (29%), Positives = 326/731 (44%), Gaps = 15/731 (2%)
Frame = +2
Query: 5 SGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHD 184
+G P P++ W +G I + V NN+ I+ ++ + +GRYTC A N+ G+A D
Sbjct: 269 TGKPDPEITWLLDGKPILPGMANVRFEDNNKKLFIDYIKPSQEGRYTCRADNQLGRAEQD 328
Query: 185 FSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLT 364
+++ PP + + + EG T+ C E + VSW KD DL
Sbjct: 329 TYVEISEPPRVVMASDKMRVV-EGRQTTIRC-----EVFGEPEPKVSWLKDGEPYTSDLL 382
Query: 365 DNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQ 544
+ S L + +A+L++ G YTCI N+AGEA +VEIL P I+ + +
Sbjct: 383 QH---STRLSYLHLREATLQDGGKYTCIGTNKAGEARTTTEVEILVAPTIEDEDRVIYGK 439
Query: 545 VAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSC 724
+P + C +G P+P+I W KNGKE+ E VL I + GK+SC
Sbjct: 440 --EGKPVQINCKASGTPYPTITWKKNGKELD--------EHNSVLTISNATREDDGKYSC 489
Query: 725 VAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGSL 904
+A N+AG + +LDV+T P ++ G + C G+P P + W K G
Sbjct: 490 LATNEAGSAVADFLLDVYTRPSFHPETTTFNIIEGHNAKIECKVDGHPKPTITWLKAGRS 549
Query: 905 IFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDGI 1084
+ + + +S +G L I K+ D G YTC A N G +E V+V P I+ + I
Sbjct: 550 L--NMNNVILSPRGDTLMILKSKRVDAGLYTCVAENTFGANEQDFKVNVFTKPYID-EAI 606
Query: 1085 DMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLSD 1264
D +P+ A + + L+C G P P + W + + D ++I V+ D
Sbjct: 607 DQTPKAVAGEKIDLKCPVLGNPTPTVYWKKGDDDIIIDGKHYELIGD--VLRIKTVTEKD 664
Query: 1265 KGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTK--QVIEGELAVIECLVEGYPAPQVS 1438
G YTC A N AG Y VDV+ P G +VIE ++C V P P ++
Sbjct: 665 TGAYTCVAINDAGQLRTNYAVDVIGKPTFDRKGENIYEVIEDHDITMDCGVTSRPLPNIA 724
Query: 1439 WLRNGNRVETGVQGVRYVT-DGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVS 1615
W R N + +Q ++ DG +TI AR D G Y C A+NEAGS+ L +LV
Sbjct: 725 WYRGDNALY--IQPHYTISEDGSQITINSARLSDGGKYTCRASNEAGSSDIEVILRILVP 782
Query: 1616 PKIITST-PGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADG--TL 1786
P+I S G L C V G P P + WT +G DI + + I A T
Sbjct: 783 PRIDKSNIIGNPLAIVARNIYLECPVTGIPQPEVYWTKDGRDI-NATDSRIIYAQNNETF 841
Query: 1787 HIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCXX 1963
IEK + Y CTA N G +F + + P + EG + C
Sbjct: 842 GIEKVQVTDAGRYTCTAVNRGGRIAHDFNLDVLSPPSFDLYRTQPTIKREGDTITLTCPI 901
Query: 1964 XXXXXXX------XXXKNGVPL--LPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKA 2119
K+ V L + ++N+ S+D + + I L + G Y+C A N+A
Sbjct: 902 KTAEDVADQVMDVSWTKDSVALDGVETDNVHISDDGRKLTIDKASLVNAGMYTCIALNRA 961
Query: 2120 GNATQKTNLNV 2152
G AT + + +
Sbjct: 962 GEATLEFKVEI 972
Score = 280 bits (715), Expect = 3e-73
Identities = 135/166 (81%), Positives = 149/166 (89%)
Frame = +2
Query: 2 ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH 181
++GIPQP+V WTK+G DIN TDSR+I AQNNETFGIE VQVTD GRYTCTA NRGG+ +H
Sbjct: 808 VTGIPQPEVYWTKDGRDINATDSRIIYAQNNETFGIEKVQVTDAGRYTCTAVNRGGRIAH 867
Query: 182 DFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDL 361
DF+LDVLSPP FD++ TQPTIKREGDTITLTCPIK AED+ADQVMDVSWTKDS ALDG
Sbjct: 868 DFNLDVLSPPSFDLYRTQPTIKREGDTITLTCPIKTAEDVADQVMDVSWTKDSVALDGVE 927
Query: 362 TDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEIL 499
TDNV ISDDGRKLTI +ASL NAG+YTCIALNRAGEA+LEFKVEIL
Sbjct: 928 TDNVHISDDGRKLTIDKASLVNAGMYTCIALNRAGEATLEFKVEIL 973
Score = 262 bits (669), Expect = 7e-68
Identities = 208/781 (26%), Positives = 334/781 (42%), Gaps = 31/781 (3%)
Frame = +2
Query: 422 ENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPTIMRCAVTG-HPF 598
E AG YTCIA N+AG + + VE+ PP + + V + C + +
Sbjct: 124 EAAGRYTCIAENKAGRSEKDMIVEVQVPPKMKQANQTFD--VEEGGTLTLECPIENPNGA 181
Query: 599 PSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVF 778
I W + D +I G L I++ A +++C A N+AG +++
Sbjct: 182 RVIYWYTDAIGKVDPNRSQISGDGTKLFIIQAQESDADRYTCRAHNEAGQDSSVFTVNLL 241
Query: 779 TPPVVSVKSDNPIKALGET-ITLFCNASGNPYPQLKWAKGGSLIFDSPDGARISLKGARL 955
PP + ++ + + + T + L C +G P P++ W G I R +L
Sbjct: 242 KPPTIPGEAFSTTEIVSNTTMELNCQPTGKPDPEITWLLDGKPILPGMANVRFEDNNKKL 301
Query: 956 DIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCL 1135
I ++K + G YTC+A N G +E V++ PP + M R+ + T++C
Sbjct: 302 FIDYIKPSQEGRYTCRADNQLGRAEQDTYVEISEPPRVVMASDKM--RVVEGRQTTIRCE 359
Query: 1136 AQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNL 1315
G+P P++ W +G T + ++ +++ + +L D G YTC N AG
Sbjct: 360 VFGEPEPKVSWLKDGEPYTSDL--LQHSTRLSYLHLREATLQDGGKYTCIGTNKAGEART 417
Query: 1316 MYNVDVVQAPVISNGGTKQVI---EGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVR 1486
V+++ AP I + +VI EG+ I C G P P ++W +NG ++
Sbjct: 418 TTEVEILVAPTIED--EDRVIYGKEGKPVQINCKASGTPYPTITWKKNGKELD------- 468
Query: 1487 YVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSSGS 1666
+LTI A D G Y C ATNEAGSA + L+V P T G
Sbjct: 469 --EHNSVLTISNATREDDGKYSCLATNEAGSAVADFLLDVYTRPSFHPETT-TFNIIEGH 525
Query: 1667 KFSLPCAVRGYPDPIISW-----TLNGNDIKDGENGHTIGADGTLHIEKAEERHLIYECT 1831
+ C V G+P P I+W +LN N++ G T+ + ++ +Y C
Sbjct: 526 NAKIECKVDGHPKPTITWLKAGRSLNMNNVILSPRGDTLMILKSKRVDAG-----LYTCV 580
Query: 1832 AKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCXXXXXXXXXXXXKNGVPL 2011
A+N GA+ +F V P I + ++ G + +KC K G
Sbjct: 581 AENTFGANEQDFKVNVFTKPYIDEAIDQTPKAVAGEKIDLKCPVLGNPTPTVYWKKG--- 637
Query: 2012 LPSNNLIFSEDYKLI----KILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVAPK-IME 2176
+ +I + Y+LI +I + D G Y+C A N AG +TN V V K +
Sbjct: 638 -DDDIIIDGKHYELIGDVLRIKTVTEKDTGAYTCVAINDAGQL--RTNYAVDVIGKPTFD 694
Query: 2177 RPRTQV--VHKGDQVTLWCEASGVPQPAITWYK-DNELLTNTGVDETATTKKKSVIFSSI 2347
R + V + +T+ C + P P I WY+ DN L T + + +S
Sbjct: 695 RKGENIYEVIEDHDITMDCGVTSRPLPNIAWYRGDNALYIQP--HYTISEDGSQITINSA 752
Query: 2348 SPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNP----RQTVFLSCNATG 2515
S G YTC+A N S++ ++ L +++PP + ++ N+ NP + ++L C TG
Sbjct: 753 RLSDGGKYTCRASNEAGSSDIEVILRILVPPRI--DKSNIIGNPLAIVARNIYLECPVTG 810
Query: 2516 IPEPVISWMRDSN---------IAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAG 2668
IP+P + W +D I QNNE T I V D G Y C A + G
Sbjct: 811 IPQPEVYWTKDGRDINATDSRIIYAQNNE-------TFGIEKVQVTDAGRYTCTAVNRGG 863
Query: 2669 Q 2671
+
Sbjct: 864 R 864
Score = 257 bits (657), Expect = 2e-66
Identities = 184/639 (28%), Positives = 285/639 (43%), Gaps = 12/639 (1%)
Frame = +2
Query: 2 ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH 181
+ G P+P V W K+G T + + + + D G+YTC TN+ G+A
Sbjct: 360 VFGEPEPKVSWLKDGEPY--TSDLLQHSTRLSYLHLREATLQDGGKYTCIGTNKAGEART 417
Query: 182 DFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDL 361
+++L P + + +EG + + C ++W K+ + LD
Sbjct: 418 TTEVEILVAPTIEDED-RVIYGKEGKPVQINCKAS-----GTPYPTITWKKNGKELD--- 468
Query: 362 TDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQP 541
+ LTIS A+ E+ G Y+C+A N AG A +F +++ + P
Sbjct: 469 -------EHNSVLTISNATREDDGKYSCLATNEAGSAVADFLLDVYTRPSFHPETTTFN- 520
Query: 542 QVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWS 721
+ + C V GHP P+I WLK G+ + + N+ + +G L IL++ AG ++
Sbjct: 521 -IIEGHNAKIECKVDGHPKPTITWLKAGRSLNMN-NVILSPRGDTLMILKSKRVDAGLYT 578
Query: 722 CVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKAL-GETITLFCNASGNPYPQLKWAKGG 898
CVAEN G E + ++VFT P + D KA+ GE I L C GNP P + W KG
Sbjct: 579 CVAENTFGANEQDFKVNVFTKPYIDEAIDQTPKAVAGEKIDLKCPVLGNPTPTVYWKKGD 638
Query: 899 SLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRD 1078
I DG L G L I + + D G YTC A+N AG + +VDV+ P +R
Sbjct: 639 DDIII--DGKHYELIGDVLRIKTVTEKDTGAYTCVAINDAGQLRTNYAVDVIGKPTFDRK 696
Query: 1079 GIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSL 1258
G ++ + +T+ C +P+P + W AL + P T++ D + I IN+ L
Sbjct: 697 GENIYEVIE-DHDITMDCGVTSRPLPNIAWYRGDNAL-YIQPHYTISEDGSQITINSARL 754
Query: 1259 SDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNG---GTKQVIEGELAVIECLVEGYPAP 1429
SD G YTC A N AGS ++ + ++ P I G I +EC V G P P
Sbjct: 755 SDGGKYTCRASNEAGSSDIEVILRILVPPRIDKSNIIGNPLAIVARNIYLECPVTGIPQP 814
Query: 1430 QVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVL 1609
+V W ++G + + Y + I + + D+G Y C+A N G + L+VL
Sbjct: 815 EVYWTKDGRDINATDSRIIYAQNNETFGIEKVQVTDAGRYTCTAVNRGGRIAHDFNLDVL 874
Query: 1610 VSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPI-----ISWTLNGN--DIKDGENGHTI 1768
P G +L C ++ D +SWT + D + +N H
Sbjct: 875 SPPSFDLYRTQPTIKREGDTITLTCPIKTAEDVADQVMDVSWTKDSVALDGVETDNVHIS 934
Query: 1769 GADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTI 1882
L I+KA + +Y C A N AG TLEF V+ +
Sbjct: 935 DDGRKLTIDKASLVNAGMYTCIALNRAGEATLEFKVEIL 973
Score = 255 bits (652), Expect = 6e-66
Identities = 199/779 (25%), Positives = 336/779 (42%), Gaps = 18/779 (2%)
Frame = +2
Query: 107 IENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIK 286
I Q +D RYTC A N G+ S F++++L PP T T+ L C
Sbjct: 210 IIQAQESDADRYTCRAHNEAGQDSSVFTVNLLKPPTIPGEAFSTTEIVSNTTMELNC--- 266
Query: 287 LAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDGRKLTISQASLENAGLYTCIALNRAG 466
+ +++W D + + + NV D+ +KL I G YTC A N+ G
Sbjct: 267 --QPTGKPDPEITWLLDGKPILPGMA-NVRFEDNNKKLFIDYIKPSQEGRYTCRADNQLG 323
Query: 467 EASLEFKVEILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDE 646
A + VEI PP + ++ + + +V + T +RC V G P P + WLK+G+ T D
Sbjct: 324 RAEQDTYVEISEPPRVVMASDKM--RVVEGRQTTIRCEVFGEPEPKVSWLKDGEPYTSD- 380
Query: 647 NIRIVEQGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKAL 826
++ + L + GK++C+ N AG +++ P + +
Sbjct: 381 LLQHSTRLSYLHLREATLQDGGKYTCIGTNKAGEARTTTEVEILVAPTIEDEDRVIYGKE 440
Query: 827 GETITLFCNASGNPYPQLKWAKGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQA 1006
G+ + + C ASG PYP + W K +G + + L I + + D G Y+C A
Sbjct: 441 GKPVQINCKASGTPYPTITWKK---------NGKELDEHNSVLTISNATREDDGKYSCLA 491
Query: 1007 LNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTA 1186
N AG++ A +DV P + + + + + ++C G P P + W G +
Sbjct: 492 TNEAGSAVADFLLDVYTRPSFHPETTTFN--IIEGHNAKIECKVDGHPKPTITWLKAGRS 549
Query: 1187 LTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNG-- 1360
L + ++ D+ + I D G+YTC AEN G++ + V+V P I
Sbjct: 550 LNMNNVILSPRGDT--LMILKSKRVDAGLYTCVAENTFGANEQDFKVNVFTKPYIDEAID 607
Query: 1361 GTKQVIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDS 1540
T + + GE ++C V G P P V W + + + + G Y G +L I D+
Sbjct: 608 QTPKAVAGEKIDLKCPVLGNPTPTVYWKKGDDDII--IDGKHYELIGDVLRIKTVTEKDT 665
Query: 1541 GIYLCSATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISW 1720
G Y C A N+AG + Y ++V+ P + ++ C V P P I+W
Sbjct: 666 GAYTCVAINDAGQLRTNYAVDVIGKPTFDRKGENIYEVIEDHDITMDCGVTSRPLPNIAW 725
Query: 1721 TLNGNDIKDGENGHTIGADG---TLHIEKAEERHLIYECTAKNDAGADTLEFPVQTIVAP 1891
G++ + +TI DG T++ + + Y C A N+AG+ +E ++ +V P
Sbjct: 726 -YRGDNALYIQPHYTISEDGSQITINSARLSDGGK-YTCRASNEAGSSDIEVILRILVPP 783
Query: 1892 KISTS---GNRYINGSEGTETVIKC-XXXXXXXXXXXXKNGVPL-LPSNNLIFSEDYKLI 2056
+I S GN ++C K+G + + +I++++ +
Sbjct: 784 RIDKSNIIGNPL--AIVARNIYLECPVTGIPQPEVYWTKDGRDINATDSRIIYAQNNETF 841
Query: 2057 KILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQ--VVHKGDQVTLWCE 2230
I +++D G Y+CTA N+ G NL+V ++P + RTQ + +GD +TL C
Sbjct: 842 GIEKVQVTDAGRYTCTAVNRGGRIAHDFNLDV-LSPPSFDLYRTQPTIKREGDTITLTCP 900
Query: 2231 ASGVPQPA-----ITWYKDNELLTNTGVDET-ATTKKKSVIFSSISPSQAGVYTCKAEN 2389
A ++W KD+ L D + + + S AG+YTC A N
Sbjct: 901 IKTAEDVADQVMDVSWTKDSVALDGVETDNVHISDDGRKLTIDKASLVNAGMYTCIALN 959
Score = 244 bits (624), Expect = 1e-62
Identities = 216/873 (24%), Positives = 367/873 (41%), Gaps = 40/873 (4%)
Frame = +2
Query: 674 VLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCN 853
+L+IL S+ AG+++C+AEN AG E +M+++V PP + + G T+TL C
Sbjct: 116 ILKILE-GSEAAGRYTCIAENKAGRSEKDMIVEVQVPPKMKQANQTFDVEEGGTLTLECP 174
Query: 854 ASGNPYPQLKWAKGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEA 1033
++ + ++ P+ ++IS G +L I +++D YTC+A N AG +
Sbjct: 175 IENPNGARVIYWYTDAIGKVDPNRSQISGDGTKLFIIQAQESDADRYTCRAHNEAGQDSS 234
Query: 1034 SVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGIT 1213
+V++L PP I + + + + ++ L C GKP P++ W L+G + +
Sbjct: 235 VFTVNLLKPPTIPGEAFS-TTEIVSNTTMELNCQPTGKPDPEITWLLDGKPILPGMANVR 293
Query: 1214 VASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAP-VISNGGTKQVIEGEL 1390
++ + I+ + S +G YTC A+N G V++ + P V+ +V+EG
Sbjct: 294 FEDNNKKLFIDYIKPSQEGRYTCRADNQLGRAEQDTYVEISEPPRVVMASDKMRVVEGRQ 353
Query: 1391 AVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNE 1570
I C V G P P+VSWL++G + + +++ T L + EA D G Y C TN+
Sbjct: 354 TTIRCEVFGEPEPKVSWLKDGEPYTSDL--LQHSTRLSYLHLREATLQDGGKYTCIGTNK 411
Query: 1571 AGSAQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDG 1750
AG A+ +E+LV+P I V+ G + C G P P I+W NG ++ +
Sbjct: 412 AGEARTTTEVEILVAP-TIEDEDRVIYGKEGKPVQINCKASGTPYPTITWKKNGKELDEH 470
Query: 1751 ENGHTIGADGTLHIEKAEERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGS 1930
+ TI E Y C A N+AG+ +F + P + N
Sbjct: 471 NSVLTIS-------NATREDDGKYSCLATNEAGSAVADFLLDVYTRPSFHPETTTF-NII 522
Query: 1931 EGTETVIKCXXXXXXXXXXXXKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAA 2110
EG I+C L NN+I S + IL ++ D G Y+C A
Sbjct: 523 EGHNAKIECKVDGHPKPTITWLKAGRSLNMNNVILSPRGDTLMILKSKRVDAGLYTCVAE 582
Query: 2111 NKAGNATQKTNLNVGVAPKIMER-PRTQVVHKGDQVTLWCEASGVPQPAITWYK-DNELL 2284
N G Q +NV P I E +T G+++ L C G P P + W K D++++
Sbjct: 583 NTFGANEQDFKVNVFTKPYIDEAIDQTPKAVAGEKIDLKCPVLGNPTPTVYWKKGDDDII 642
Query: 2285 TNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMN 2464
+ E + +++ G YTC A N + + V+ P + N
Sbjct: 643 IDGKHYELIGDVLR---IKTVTEKDTGAYTCVAINDAGQLRTNYAVDVIGKPTFDRKGEN 699
Query: 2465 V-STNPRQTVFLSCNATGIPEPVISWMR-DSNIAIQNNEKYQILGTTLAIRNVLPDDDGF 2638
+ + + C T P P I+W R D+ + IQ + G+ + I + D G
Sbjct: 700 IYEVIEDHDITMDCGVTSRPLPNIAWYRGDNALYIQPHYTISEDGSQITINSARLSDGGK 759
Query: 2639 YHCIAKSDAGQ-------------KIATRKLIVNKPSDRPAPIWVECDEKGKPKKTEYMI 2779
Y C A ++AG +I +I N + I++EC G P+ Y
Sbjct: 760 YTCRASNEAGSSDIEVILRILVPPRIDKSNIIGNPLAIVARNIYLECPVTGIPQPEVYWT 819
Query: 2780 DRGDTPDDNPQLLPWKD------VEDSSLNGSIAYRCMPGPRSSR-----TVLLHAAPQF 2926
G + + + +E + + Y C R R + + + P F
Sbjct: 820 KDGRDINATDSRIIYAQNNETFGIEKVQVTDAGRYTCTAVNRGGRIAHDFNLDVLSPPSF 879
Query: 2927 -IVKPKNTTAAIGAIVELRC-----SAAGPPHPTITWAKDGKL---IEDSKFEIAYSHLK 3079
+ + + T G + L C ++W KD +E I+ K
Sbjct: 880 DLYRTQPTIKREGDTITLTCPIKTAEDVADQVMDVSWTKDSVALDGVETDNVHISDDGRK 939
Query: 3080 VTLNSTS--DSGEYTCMAQNSVGSSTVSAFINV 3172
+T++ S ++G YTC+A N G +T+ + +
Sbjct: 940 LTIDKASLVNAGMYTCIALNRAGEATLEFKVEI 972
Score = 241 bits (616), Expect = 1e-61
Identities = 209/857 (24%), Positives = 347/857 (40%), Gaps = 48/857 (5%)
Frame = +2
Query: 986 GDYTCQALNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMR 1165
G YTC A N AG SE + V+V VPP++ + + + + +LTL+C + ++
Sbjct: 127 GRYTCIAENKAGRSEKDMIVEVQVPPKMKQ--ANQTFDVEEGGTLTLECPIENPNGARVI 184
Query: 1166 WTLNGTALTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAP 1345
+ ++ D T + I SD YTC A N AG D+ ++ V++++ P
Sbjct: 185 YWYTDAIGKVDPNRSQISGDGTKLFIIQAQESDADRYTCRAHNEAGQDSSVFTVNLLKPP 244
Query: 1346 VISNGG--TKQVIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTII 1519
I T +++ + C G P P+++WL +G + G+ VR+ + + L I
Sbjct: 245 TIPGEAFSTTEIVSNTTMELNCQPTGKPDPEITWLLDGKPILPGMANVRFEDNNKKLFID 304
Query: 1520 EARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGY 1699
+ G Y C A N+ G A+Q +E+ P+++ ++ + G + ++ C V G
Sbjct: 305 YIKPSQEGRYTCRADNQLGRAEQDTYVEISEPPRVVMAS-DKMRVVEGRQTTIRCEVFGE 363
Query: 1700 PDPIISWTLNGNDIKDGENGHTIGADGTLHIEKAE-ERHLIYECTAKNDAGADTLEFPVQ 1876
P+P +SW +G H+ LH+ +A + Y C N AG V+
Sbjct: 364 PEPKVSWLKDGEPYTSDLLQHSTRL-SYLHLREATLQDGGKYTCIGTNKAGEARTTTEVE 422
Query: 1877 TIVAPKISTSGNRYINGSEGTETVIKCXXXXXXXXXXXXKNGVPLLPSNNLIFSEDYKLI 2056
+VAP I +R I G EG I C K N E ++
Sbjct: 423 ILVAPTIEDE-DRVIYGKEGKPVQINCKASGTPYPTITWK-------KNGKELDEHNSVL 474
Query: 2057 KILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEAS 2236
I + D G+YSC A N+AG+A L+V P T + +G + C+
Sbjct: 475 TISNATREDDGKYSCLATNEAGSAVADFLLDVYTRPSFHPETTTFNIIEGHNAKIECKVD 534
Query: 2237 GVPQPAITWYKDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDI 2416
G P+P ITW K L V + + +++ AG+YTC AEN + E+D
Sbjct: 535 GHPKPTITWLKAGRSLNMNNV--ILSPRGDTLMILKSKRVDAGLYTCVAENTFGANEQDF 592
Query: 2417 DLIVMIPPEVVPERMNVSTNPR----QTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQ 2584
+ V P + + P+ + + L C G P P + W + + I + + Y+
Sbjct: 593 KVNVFTKPYIDEA---IDQTPKAVAGEKIDLKCPVLGNPTPTVYWKKGDDDIIIDGKHYE 649
Query: 2585 ILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKL-IVNKPS-DRPA----------PI 2728
++G L I+ V D G Y C+A +DAGQ + ++ KP+ DR I
Sbjct: 650 LIGDVLRIKTVTEKDTGAYTCVAINDAGQLRTNYAVDVIGKPTFDRKGENIYEVIEDHDI 709
Query: 2729 WVECDEKGKP---------KKTEYMIDRGDTPDDNPQLLPWKDVEDSSLNGSIAYRCM-- 2875
++C +P Y+ +D Q+ + + L+ Y C
Sbjct: 710 TMDCGVTSRPLPNIAWYRGDNALYIQPHYTISEDGSQI----TINSARLSDGGKYTCRAS 765
Query: 2876 --PGPRSSRTVLLHAAPQFIVKPK---NTTAAIGAIVELRCSAAGPPHPTITWAKDGKLI 3040
G +L P I K N A + + L C G P P + W KDG+ I
Sbjct: 766 NEAGSSDIEVILRILVPPRIDKSNIIGNPLAIVARNIYLECPVTGIPQPEVYWTKDGRDI 825
Query: 3041 EDSKFEIAYSHLKVTLN----STSDSGEYTCMAQNSVGSSTVSAFINV----DNNILPTP 3196
+ I Y+ T +D+G YTC A N G ++V ++ T
Sbjct: 826 NATDSRIIYAQNNETFGIEKVQVTDAGRYTCTAVNRGGRIAHDFNLDVLSPPSFDLYRTQ 885
Query: 3197 KPSSNQKNVAVITC----YERNQAYSRGLTWEYNGVPMP-KNLAGIHFMNNGSLVILDTS 3361
+ + +TC E ++W + V + +H ++G + +D +
Sbjct: 886 PTIKREGDTITLTCPIKTAEDVADQVMDVSWTKDSVALDGVETDNVHISDDGRKLTIDKA 945
Query: 3362 SLKEGDLELYTCKVRNR 3412
SL +YTC NR
Sbjct: 946 SLVNAG--MYTCIALNR 960
Score = 198 bits (503), Expect = 1e-48
Identities = 222/872 (25%), Positives = 336/872 (38%), Gaps = 63/872 (7%)
Frame = +2
Query: 1268 GVYTCYAENVAGSDNLMYNVDVVQAPVISNGG-TKQVIEGELAVIECLVEGYPAPQVSWL 1444
G YTC AEN AG V+V P + T V EG +EC +E +V +
Sbjct: 127 GRYTCIAENKAGRSEKDMIVEVQVPPKMKQANQTFDVEEGGTLTLECPIENPNGARVIYW 186
Query: 1445 RNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPKI 1624
+ + DG L II+A+ D+ Y C A NEAG +T+ +L P I
Sbjct: 187 YTDAIGKVDPNRSQISGDGTKLFIIQAQESDADRYTCRAHNEAGQDSSVFTVNLLKPPTI 246
Query: 1625 ITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDG-------ENGHTIGADGT 1783
S + L C G PDP I+W L+G I G +N + D
Sbjct: 247 PGEAFSTTEIVSNTTMELNCQPTGKPDPEITWLLDGKPILPGMANVRFEDNNKKLFID-- 304
Query: 1784 LHIEKAEERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCXX 1963
+I+ ++E Y C A N G + V+ P++ + ++ + EG +T I+C
Sbjct: 305 -YIKPSQEGR--YTCRADNQLGRAEQDTYVEISEPPRVVMASDK-MRVVEGRQTTIRCEV 360
Query: 1964 XXXXXXXXX-XKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQKT 2140
K+G P S+ L S + + L D G+Y+C NKAG A T
Sbjct: 361 FGEPEPKVSWLKDGEPYT-SDLLQHSTRLSYLHLREATLQDGGKYTCIGTNKAGEARTTT 419
Query: 2141 NLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATTK 2320
+ + VAP I + R +G V + C+ASG P P ITW K+ + L DE +
Sbjct: 420 EVEILVAPTIEDEDRVIYGKEGKPVQINCKASGTPYPTITWKKNGKEL-----DEHNSV- 473
Query: 2321 KKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFLS 2500
+ S+ + G Y+C A N S D L V P PE + +
Sbjct: 474 ---LTISNATREDDGKYSCLATNEAGSAVADFLLDVYTRPSFHPETTTFNIIEGHNAKIE 530
Query: 2501 CNATGIPEPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIA 2680
C G P+P I+W++ NN G TL I D G Y C+A++ G
Sbjct: 531 CKVDGHPKPTITWLKAGRSLNMNNVILSPRGDTLMILKSKRVDAGLYTCVAENTFGANEQ 590
Query: 2681 TRKL-IVNKPSDRPA-----------PIWVECDEKGKPKKTEY-------MIDRGDTPDD 2803
K+ + KP A I ++C G P T Y +I G +
Sbjct: 591 DFKVNVFTKPYIDEAIDQTPKAVAGEKIDLKCPVLGNPTPTVYWKKGDDDIIIDGKHYEL 650
Query: 2804 NPQLLPWKDVEDSSLNGSIAYRCMP-----GPRSSRTVLLHAAPQFIVKPKNTTAAI-GA 2965
+L K V + AY C+ R++ V + P F K +N I
Sbjct: 651 IGDVLRIKTVTEKDTG---AYTCVAINDAGQLRTNYAVDVIGKPTFDRKGENIYEVIEDH 707
Query: 2966 IVELRCSAAGPPHPTITWAK-DGKLIEDSKFEIAYSHLKVTLNST--SDSGEYTCMAQNS 3136
+ + C P P I W + D L + I+ ++T+NS SD G+YTC A N
Sbjct: 708 DITMDCGVTSRPLPNIAWYRGDNALYIQPHYTISEDGSQITINSARLSDGGKYTCRASNE 767
Query: 3137 VGSSTVSAFINV-------DNNILPTPKP--SSNQKNVAVITCYERNQAYSRGLTWEYNG 3289
GSS + + + +NI+ P + N +T + + Y W +G
Sbjct: 768 AGSSDIEVILRILVPPRIDKSNIIGNPLAIVARNIYLECPVTGIPQPEVY-----WTKDG 822
Query: 3290 VPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRR---RHSI------PHLTS 3442
+ + I + N ++ ++ D YTC NR H P
Sbjct: 823 RDINATDSRIIYAQNNETFGIE--KVQVTDAGRYTCTAVNRGGRIAHDFNLDVLSPPSFD 880
Query: 3443 AFEGVPEVKTIDKVEVNNGDSVVLDCEV-TSDPLTTHVV---WTKNDQKMLD----DDAI 3598
+ P +K GD++ L C + T++ + V+ WTK D LD D+
Sbjct: 881 LYRTQPTIK-------REGDTITLTCPIKTAEDVADQVMDVSWTK-DSVALDGVETDNVH 932
Query: 3599 YXXXXXXXXXXXXEKYDEGVYKCVASNSIGKA 3694
+ G+Y C+A N G+A
Sbjct: 933 ISDDGRKLTIDKASLVNAGMYTCIALNRAGEA 964
Score = 143 bits (360), Expect = 5e-32
Identities = 146/603 (24%), Positives = 247/603 (40%), Gaps = 41/603 (6%)
Frame = +2
Query: 2087 GEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPA--IT 2260
G Y+C A NKAG + + + V V PK+ + +T V +G +TL C P A I
Sbjct: 127 GRYTCIAENKAGRSEKDMIVEVQVPPKMKQANQTFDVEEGGTLTLECPIEN-PNGARVIY 185
Query: 2261 WYKDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPP 2440
WY D + + + K I + S A YTC+A N A + + + ++ P
Sbjct: 186 WYTDAIGKVDPNRSQISGDGTKLFIIQA-QESDADRYTCRAHN-EAGQDSSVFTVNLLKP 243
Query: 2441 EVVPERMNVSTN--PRQTVFLSCNATGIPEPVISWMRDSNIAIQN--NEKYQILGTTLAI 2608
+P +T T+ L+C TG P+P I+W+ D + N +++ L I
Sbjct: 244 PTIPGEAFSTTEIVSNTTMELNCQPTGKPDPEITWLLDGKPILPGMANVRFEDNNKKLFI 303
Query: 2609 RNVLPDDDGFYHCIAKSDAGQKIATRKLIVNKP------SDRPAPI-----WVECDEKGK 2755
+ P +G Y C A + G+ + +++P SD+ + + C+ G+
Sbjct: 304 DYIKPSQEGRYTCRADNQLGRAEQDTYVEISEPPRVVMASDKMRVVEGRQTTIRCEVFGE 363
Query: 2756 PKKTEYMIDRGD--TPD--DNPQLLPWKDVEDSSLNGSIAYRCMPG-----PRSSRTVLL 2908
P+ + G+ T D + L + + +++L Y C+ R++ V +
Sbjct: 364 PEPKVSWLKDGEPYTSDLLQHSTRLSYLHLREATLQDGGKYTCIGTNKAGEARTTTEVEI 423
Query: 2909 HAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEIAYSHLKVTL 3088
AP + + G V++ C A+G P+PTITW K+GK +++ S L ++
Sbjct: 424 LVAPTIEDEDRVIYGKEGKPVQINCKASGTPYPTITWKKNGKELDEHN-----SVLTISN 478
Query: 3089 NSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNV-----AVITCYERNQ 3253
+ D G+Y+C+A N GS+ ++V P+ P + N+ A I C
Sbjct: 479 ATREDDGKYSCLATNEAGSAVADFLLDVYTR--PSFHPETTTFNIIEGHNAKIECKVDGH 536
Query: 3254 AYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNR------- 3412
+TW G + N+ + G +++ S K D LYTC N
Sbjct: 537 PKPT-ITWLKAGRSL--NMNNVILSPRGDTLMILKS--KRVDAGLYTCVAENTFGANEQD 591
Query: 3413 ---RRHSIPHLTSAFEGVPEVKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKML 3583
+ P++ A + P+ +K++ L C V +P T V W K D ++
Sbjct: 592 FKVNVFTKPYIDEAIDQTPKAVAGEKID--------LKCPVLGNPTPT-VYWKKGDDDII 642
Query: 3584 DDDAIYXXXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNVYEGDFLPLTGFEGSG 3763
D Y + D G Y CVA N G+ + Y D + F+ G
Sbjct: 643 IDGKHYELIGDVLRIKTVTEKDTGAYTCVAINDAGQLRTN-----YAVDVIGKPTFDRKG 697
Query: 3764 INI 3772
NI
Sbjct: 698 ENI 700
Score = 104 bits (259), Expect = 2e-20
Identities = 130/562 (23%), Positives = 217/562 (38%), Gaps = 53/562 (9%)
Frame = +2
Query: 2309 ATTKKKSVIFSSISPSQA-GVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQ 2485
A K +I + S+A G YTC AEN +E+D+ + V +PP++
Sbjct: 108 AAAVKFPIILKILEGSEAAGRYTCIAENKAGRSEKDMIVEVQVPPKMKQANQTFDVEEGG 167
Query: 2486 TVFLSC---NATGIPEPVISWMRDSNIAIQNNEKYQILG--TTLAIRNVLPDDDGFYHCI 2650
T+ L C N G VI W D+ + N QI G T L I D Y C
Sbjct: 168 TLTLECPIENPNGAR--VIYWYTDAIGKVDPNRS-QISGDGTKLFIIQAQESDADRYTCR 224
Query: 2651 AKSDAGQKIATRKLIVNKPSDRPAPIW------------VECDEKGKPK-KTEYMIDRGD 2791
A ++AGQ + + + KP P + + C GKP + +++D
Sbjct: 225 AHNEAGQDSSVFTVNLLKPPTIPGEAFSTTEIVSNTTMELNCQPTGKPDPEITWLLDGKP 284
Query: 2792 T---------PDDNPQLLPWKDVEDSSLNGSIAYRCMPGPRSSRT-----VLLHAAPQFI 2929
D+N +L + D S G Y C + R V + P+ +
Sbjct: 285 ILPGMANVRFEDNNKKL--FIDYIKPSQEGR--YTCRADNQLGRAEQDTYVEISEPPRVV 340
Query: 2930 VKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGK-----LIEDSKFEIAYSHLKVTLNS 3094
+ G +RC G P P ++W KDG+ L++ S ++Y HL+ +
Sbjct: 341 MASDKMRVVEGRQTTIRCEVFGEPEPKVSWLKDGEPYTSDLLQHST-RLSYLHLREA--T 397
Query: 3095 TSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSN-----QKNVAVITCYERNQAY 3259
D G+YTC+ N G + + + + + PT + + I C Y
Sbjct: 398 LQDGGKYTCIGTNKAGEARTTTEVEI--LVAPTIEDEDRVIYGKEGKPVQINCKASGTPY 455
Query: 3260 SRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRHSIP--- 3430
+TW+ NG + ++ N L I + + +G Y+C N ++
Sbjct: 456 PT-ITWKKNGKELDEH--------NSVLTISNATREDDGK---YSCLATNEAGSAVADFL 503
Query: 3431 ---HLTSAFEGVPEVKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIY 3601
+ +F PE T + +E G + ++C+V P T + W K + + ++ I
Sbjct: 504 LDVYTRPSFH--PETTTFNIIE---GHNAKIECKVDGHPKPT-ITWLKAGRSLNMNNVIL 557
Query: 3602 XXXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNV----YEGDFLPLTGFEGSGIN 3769
++ D G+Y CVA N+ G D ++NV Y + + T +G
Sbjct: 558 SPRGDTLMILKSKRVDAGLYTCVAENTFGANEQDFKVNVFTKPYIDEAIDQTPKAVAGEK 617
Query: 3770 IDDSSNAGGSSRREAYKKENED 3835
ID G+ Y K+ +D
Sbjct: 618 IDLKCPVLGNPTPTVYWKKGDD 639