Homology by BLASTX


BLASTX 2.2.4 [Aug-26-2002]
Query= T09B9_2
         (4738 letters)

Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
           1,967,186 sequences; 661,712,633 total letters


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7499207|pir||T20992 hypothetical protein F15G9.4a - Caenorhab...  3104   0.0
gi|17568541|ref|NP_509635.1| high Incidence of Males due to incr...  3091   0.0
gi|39596105|emb|CAE69741.1| Hypothetical protein CBG16014 [Caeno...  2274   0.0
gi|31083306|ref|NP_114141.1| hemicentin; fibulin 6 [Homo sapiens]     475   e-132
gi|14575679|gb|AAK68690.1| hemicentin [Homo sapiens]                  473   e-131
gi|13872813|emb|CAC37630.1| fibulin-6 [Homo sapiens]                  472   e-131
gi|38073489|ref|XP_136261.3| similar to hemicentin; fibulin 6 [M...   444   e-123
gi|47222186|emb|CAG11612.1| unnamed protein product [Tetraodon n...   440   e-121
gi|47214649|emb|CAG05169.1| unnamed protein product [Tetraodon n...   439   e-121
gi|34880529|ref|XP_222716.2| similar to hemicentin; fibulin 6 [R...   427   e-118
gi|41148814|ref|XP_175125.4| hemicentin-2 [Homo sapiens]              409   e-112
gi|16551993|dbj|BAB71216.1| unnamed protein product [Homo sapiens]    396   e-108
gi|39596128|emb|CAE69764.1| Hypothetical protein CBG16045 [Caeno...   380   e-103
gi|34853544|ref|XP_231135.2| similar to hypothetical protein [Ra...   376   e-102
gi|21739606|emb|CAD38854.1| hypothetical protein [Homo sapiens]       362   6e-98
gi|7512404|pir||I38346 elastic titin - human (fragment) >gnl|BL_...   312   4e-83
gi|17066105|emb|CAD12456.1| Titin [Homo sapiens]                      312   4e-83
gi|50659088|ref|NP_596869.2| titin isoform N2-A; connectin; CMH9...   312   4e-83
gi|37623931|gb|AAP80789.2| cardiac titin N2BA isoform [Rattus no...   312   4e-83
gi|33413750|gb|AAN11323.1| cardiac titin [Canis familiaris]           310   2e-82
gi|47222185|emb|CAG11611.1| unnamed protein product [Tetraodon n...   295   7e-78
gi|47214568|emb|CAG13290.1| unnamed protein product [Tetraodon n...   269   6e-70
gi|48095560|ref|XP_392317.1| similar to ENSANGP00000018214 [Apis...   268   7e-70
gi|18390319|ref|NP_056234.1| adlican [Homo sapiens] >gnl|BL_ORD_...   265   8e-69
gi|38490688|ref|NP_849144.2| immunoglobulin superfamily, member ...   265   8e-69
gi|11359852|pir||T42633 connectin/titin - chicken (fragment) >gn...   264   1e-68
gi|50730336|ref|XP_416853.1| PREDICTED: similar to adlican [Gall...   260   2e-67
gi|1172451|sp|Q05793|PGBM_MOUSE Basement membrane-specific hepar...   248   1e-63
gi|39586313|emb|CAE66724.1| Hypothetical protein CBG12070 [Caeno...   247   2e-63
gi|25141314|ref|NP_491290.2| UNCoordinated locomotion UNC-89, PH...   244   1e-62
gi|31746683|gb|AAP68958.1| Uncoordinated protein 89, isoform b [...   244   1e-62
gi|38454276|ref|NP_942063.1| bone specific CMF608 [Rattus norveg...   244   2e-62
gi|38076522|ref|XP_143254.3| similar to bone specific CMF608 [Mu...   241   2e-61
gi|539611|pir||A38096 perlecan precursor - human >gnl|BL_ORD_ID|...   234   2e-59
gi|1160355|gb|AAB00542.1| UNC-89                                      234   2e-59
gi|24212664|sp|P98160|PGBM_HUMAN Basement membrane-specific hepa...   233   3e-59
gi|11602963|emb|CAC18534.1| heparan sulfate proteoglycan perleca...   233   3e-59
gi|7511618|pir||T29757 protein UNC-89 - Caenorhabditis elegans        232   6e-59
gi|7427517|ref|NP_005520.2| heparan sulfate proteoglycan 2; hepa...   229   4e-58
gi|34872189|ref|XP_233606.2| similar to Basement membrane-specif...   223   3e-56
gi|16551710|dbj|BAB71154.1| unnamed protein product [Homo sapiens]    221   1e-55
gi|24762491|ref|NP_611867.1| CG30171-PB [Drosophila melanogaster...   212   6e-53
gi|24586203|ref|NP_724542.1| CG17800-PC [Drosophila melanogaster...   208   1e-51
gi|8072217|gb|AAF71926.1| Dscam [Drosophila melanogaster]             207   3e-51
gi|24586205|ref|NP_724543.1| CG17800-PA [Drosophila melanogaster...   206   3e-51
gi|28573968|ref|NP_523649.5| CG17800-PD [Drosophila melanogaster...   206   6e-51
gi|24653966|ref|NP_725506.1| CG18255-PA [Drosophila melanogaster...   204   2e-50
gi|24653968|ref|NP_725507.1| CG18255-PC [Drosophila melanogaster...   204   2e-50
gi|47846181|emb|CAE51322.1| basement membrane-specific heparan s...   198   9e-49
gi|48095021|ref|XP_392224.1| similar to CG32387-PB [Apis mellifera]   193   3e-47
gi|47226798|emb|CAG06640.1| unnamed protein product [Tetraodon n...   192   7e-47
gi|200301|gb|AAA39912.1| basement membrane proteoglycan               191   1e-46
gi|31197929|ref|XP_307912.1| ENSANGP00000021854 [Anopheles gambi...   191   1e-46
gi|45552493|ref|NP_995769.1| CG17800-PE [Drosophila melanogaster...   191   2e-46
gi|47210289|emb|CAF90147.1| unnamed protein product [Tetraodon n...   189   6e-46
gi|39593042|emb|CAE64511.1| Hypothetical protein CBG09247 [Caeno...   188   9e-46
gi|25145904|ref|NP_741548.1| fibronectin, type III and protein k...   188   1e-45
gi|25145902|ref|NP_741549.1| fibronectin, type III and protein k...   188   1e-45
gi|7498954|pir||T34416 hypothetical protein F12F3.2 - Caenorhabd...   188   1e-45
gi|24620457|gb|AAN61521.1| 301KDa_2 protein [Caenorhabditis eleg...   188   1e-45
gi|24620454|gb|AAN61518.1| 2MDa_2 protein [Caenorhabditis elegans]    188   1e-45
gi|24620456|gb|AAN61520.1| 301KDa_1 protein [Caenorhabditis eleg...   188   1e-45
gi|24620453|gb|AAN61517.1| 2MDa_1 protein [Caenorhabditis elegans]    188   1e-45
gi|21751818|dbj|BAC04042.1| unnamed protein product [Homo sapiens]    185   1e-44
gi|48095869|ref|XP_392361.1| similar to CG30171-PB [Apis mellifera]   183   3e-44
gi|47229075|emb|CAG03827.1| unnamed protein product [Tetraodon n...   181   1e-43
gi|45580804|ref|NP_996024.1| CG33274-PA [Drosophila melanogaster...   181   2e-43
gi|50729979|ref|XP_416734.1| PREDICTED: similar to Down syndrome...   178   1e-42
gi|7512753|pir||T08678 hypothetical protein DKFZp564I1922.1 - hu...   177   3e-42
gi|47214648|emb|CAG05168.1| unnamed protein product [Tetraodon n...   176   4e-42
gi|47271220|gb|AAT27280.1| LP21844p [Drosophila melanogaster]         176   6e-42
gi|31213063|ref|XP_315475.1| ENSANGP00000021721 [Anopheles gambi...   176   6e-42
gi|27696508|gb|AAH31063.1| IGSF10 protein [Homo sapiens]              174   2e-41
gi|31199437|ref|XP_308666.1| ENSANGP00000011092 [Anopheles gambi...   174   2e-41
gi|48111627|ref|XP_396307.1| similar to CG31190-PB [Apis mellifera]   172   9e-41
gi|24158420|ref|NP_524643.2| CG7981-PA [Drosophila melanogaster]...   171   2e-40
gi|24655822|ref|NP_652705.1| CG1915-PC [Drosophila melanogaster]...   171   2e-40
gi|48096455|ref|XP_392460.1| similar to BMKETTIN [Apis mellifera]     171   2e-40
gi|8250181|emb|CAB93524.1| D-Titin [Drosophila melanogaster]          170   3e-40
gi|18252623|gb|AAL66361.1| roundabout-1 [Xenopus laevis]              169   6e-40
gi|24639352|ref|NP_726813.1| CG7981-PC [Drosophila melanogaster]...   169   6e-40
gi|24639356|ref|NP_726815.1| CG7981-PD [Drosophila melanogaster]...   169   6e-40
gi|18033452|gb|AAL57166.1| Down syndrome cell adhesion molecule ...   169   8e-40
gi|20521772|dbj|BAA86446.2| KIAA1132 protein [Homo sapiens]           169   8e-40
gi|2706875|dbj|BAA24032.1| NCAM-180 [Cynops pyrrhogaster]             168   1e-39
gi|21359935|ref|NP_065744.2| Down syndrome cell adhesion molecul...   168   1e-39
gi|2706876|dbj|BAA24033.1| NCAM-140 [Cynops pyrrhogaster]             168   1e-39
gi|19852060|gb|AAL99985.1| Down syndrome cell adhesion molecule-...   167   2e-39
gi|24659853|ref|NP_729225.1| CG32387-PA [Drosophila melanogaster...   167   2e-39
gi|24659848|ref|NP_729224.1| CG32387-PB [Drosophila melanogaster...   167   2e-39
gi|48129578|ref|XP_393308.1| similar to CG32387-PB [Apis mellifera]   166   5e-39
gi|47222572|emb|CAG02937.1| unnamed protein product [Tetraodon n...   166   7e-39
gi|31208927|ref|XP_313430.1| ENSANGP00000020211 [Anopheles gambi...   165   9e-39
gi|542688|pir||PN0568 connectin 3B - chicken (fragment) >gnl|BL_...   165   9e-39
gi|24371280|ref|NP_571556.1| roundabout homolog 1; roundabout (a...   165   1e-38
gi|23450943|gb|AAN32613.1| Down syndrome cell adhesion molecule ...   164   2e-38
gi|40255314|ref|NP_443075.1| obscurin, cytoskeletal calmodulin a...   164   2e-38
gi|47219381|emb|CAG01544.1| unnamed protein product [Tetraodon n...   164   2e-38
gi|38089814|ref|XP_356154.1| Down syndrome cell adhesion molecul...   163   3e-38
gi|16551976|dbj|BAB71212.1| unnamed protein product [Homo sapiens]    163   4e-38
gi|48476182|ref|NP_071765.2| roundabout, axon guidance receptor,...   162   6e-38
gi|50760218|ref|XP_425808.1| PREDICTED: similar to Down syndrome...   162   9e-38
gi|50732147|ref|XP_418501.1| PREDICTED: similar to obscurin, cyt...   162   9e-38
gi|24639354|ref|NP_726814.1| CG7981-PE [Drosophila melanogaster]...   160   3e-37
gi|49036496|sp|Q9HCK4|ROB2_HUMAN Roundabout homolog 2 precursor       160   3e-37
gi|10047201|dbj|BAB13394.1| KIAA1568 protein [Homo sapiens]           160   3e-37
gi|24639358|ref|NP_726816.1| CG7981-PB [Drosophila melanogaster]...   160   3e-37
gi|42656654|ref|XP_031246.10| roundabout, axon guidance receptor...   160   3e-37
gi|47220212|emb|CAF98977.1| unnamed protein product [Tetraodon n...   160   3e-37
gi|6946670|emb|CAB72285.1| EG:BACR25B3.10 [Drosophila melanogaster]   160   4e-37
gi|22474516|dbj|BAC10620.1| Titin-like protein [Bombyx mori]          159   5e-37
gi|18700461|dbj|BAB85198.1| Titin-like protein [Bombyx mori]          159   5e-37
gi|31201553|ref|XP_309724.1| ENSANGP00000012544 [Anopheles gambi...   159   8e-37
gi|47225054|emb|CAF97469.1| unnamed protein product [Tetraodon n...   158   1e-36
gi|23450945|gb|AAN32614.1| Down syndrome cell adhesion molecule ...   157   2e-36
gi|4506569|ref|NP_002932.1| roundabout 1 isoform a; roundabout 1...   157   2e-36
gi|19743806|ref|NP_598334.1| roundabout 1 isoform b; roundabout ...   157   2e-36
gi|20127422|ref|NP_001380.2| Down syndrome cell adhesion molecul...   157   3e-36
gi|7512400|pir||T08851 Down syndrome cell adhesion protein 1 - h...   157   3e-36
gi|7717377|emb|CAB90436.1| human CHD2-52 down syndrome cell adhe...   157   3e-36
gi|45827726|ref|NP_996770.1| Down syndrome cell adhesion molecul...   157   3e-36
gi|33469129|ref|NP_062286.1| roundabout homolog 1 [Mus musculus]...   157   3e-36
gi|18032392|gb|AAL56711.1| Down syndrome cell adhesion molecule ...   157   3e-36
gi|11559953|ref|NP_071524.1| roundabout homolog 1 [Rattus norveg...   156   4e-36
gi|18859319|ref|NP_571708.1| roundabout homolog 2 [Danio rerio] ...   156   4e-36
gi|34863083|ref|XP_236056.2| similar to rig-1 protein [Rattus no...   156   5e-36
gi|31212017|ref|XP_314993.1| ENSANGP00000021379 [Anopheles gambi...   156   5e-36
gi|34863302|ref|XP_236203.2| similar to Down syndrome cell adhes...   156   5e-36
gi|11544425|emb|CAC17584.1| bG153O3.1 (similar to C.elegans hemi...   155   9e-36
gi|47227825|emb|CAG08988.1| unnamed protein product [Tetraodon n...   155   9e-36
gi|31205013|ref|XP_311455.1| ENSANGP00000000600 [Anopheles gambi...   154   2e-35
gi|7106393|ref|NP_035378.1| roundabout homolog 3; retinoblastoma...   154   2e-35
gi|33244029|gb|AAH55333.1| Robo2 protein [Mus musculus]               154   3e-35
gi|27884114|emb|CAD61245.1| SI:dZ249N21.1.1 (novel protein simil...   154   3e-35
gi|49036483|sp|Q7TPD3|ROB2_MOUSE Roundabout homolog 2 precursor       154   3e-35
gi|26329151|dbj|BAC28314.1| unnamed protein product [Mus musculus]    153   3e-35
gi|45553395|ref|NP_996226.1| CG31190-PB [Drosophila melanogaster...   153   3e-35
gi|49036501|sp|Q9Z2I4|ROB3_MOUSE Roundabout homolog 3 precursor ...   153   4e-35
gi|50744908|ref|XP_419931.1| PREDICTED: similar to CG12002-PA [G...   152   6e-35
gi|30179887|sp|Q06561|UN52_CAEEL Basement membrane proteoglycan ...   152   8e-35
gi|50507819|emb|CAH04704.1| Hypothetical protein ZC101.2f [Caeno...   152   8e-35
gi|34858708|ref|XP_230608.2| similar to sialoadhesin [Rattus nor...   152   8e-35
gi|289722|gb|AAA28156.1| basement membrane proteoglycan               152   8e-35
gi|17536621|ref|NP_497046.1| basement membrane proteoglycan (2O9...   152   8e-35
gi|13626028|ref|NP_112451.1| Down syndrome cell adhesion molecul...   152   1e-34
gi|19424286|ref|NP_598271.1| Down syndrome cell adhesion molecul...   152   1e-34
gi|6164831|gb|AAF04558.1| Robo2 [Rattus norvegicus]                   152   1e-34
gi|47224969|emb|CAF97384.1| unnamed protein product [Tetraodon n...   151   1e-34
gi|47227738|emb|CAG08901.1| unnamed protein product [Tetraodon n...   151   2e-34
gi|24640619|ref|NP_727274.1| CG1634-PB [Drosophila melanogaster]...   150   3e-34
gi|17530861|ref|NP_511090.1| CG1634-PA [Drosophila melanogaster]...   150   3e-34
gi|47227361|emb|CAF96910.1| unnamed protein product [Tetraodon n...   150   3e-34
gi|6760654|gb|AAC28614.2| neuroglian [Drosophila melanogaster]        149   6e-34
gi|103273|pir||A32579 neuroglian - fruit fly (Drosophila melanog...   149   6e-34
gi|6760653|gb|AAC28613.2| neuroglian [Drosophila melanogaster]        149   6e-34
gi|4557707|ref|NP_000416.1| L1 cell adhesion molecule isoform 1 ...   149   8e-34
gi|31201725|ref|XP_309810.1| ENSANGP00000018214 [Anopheles gambi...   149   8e-34
gi|33354077|dbj|BAC81122.1| L1 cell adhesion molecule [Homo sapi...   149   8e-34
gi|16758574|ref|NP_446198.1| contactin 5 [Rattus norvegicus] >gn...   149   8e-34
gi|13435353|ref|NP_076493.1| L1 cell adhesion molecule isoform 2...   149   8e-34
gi|28972103|dbj|BAC65505.1| mKIAA0230 protein [Mus musculus]          148   1e-33
gi|33354079|dbj|BAC81123.1| L1 cell adhesion molecule [Pan trogl...   148   1e-33
gi|127857|sp|P13592|NCA2_HUMAN Neural cell adhesion molecule 1, ...   148   1e-33
gi|26341784|dbj|BAC34554.1| unnamed protein product [Mus musculus]    148   1e-33
gi|26349823|dbj|BAC38551.1| unnamed protein product [Mus musculus]    148   1e-33
gi|10834990|ref|NP_000606.1| neural cell adhesion molecule 1; an...   148   1e-33
gi|4732113|gb|AAD28610.1| neural cell adhesion molecule L1 [Cerc...   148   1e-33
gi|33354081|dbj|BAC81124.1| L1 cell adhesion molecule [Pongo pyg...   148   1e-33
gi|13492012|gb|AAK28043.1| transmembrane receptor Roundabout3 [D...   148   1e-33
gi|28573310|ref|NP_788286.1| CG33141-PA [Drosophila melanogaster...   147   2e-33
gi|8572742|gb|AAF77184.1| SNS [Drosophila melanogaster]               147   2e-33
gi|2181948|emb|CAA33148.1| cell adhesion molecule (AA 1 - 681) (...   147   3e-33
gi|1504040|dbj|BAA13219.1| similar to D.melanogaster peroxidasin...   146   4e-33
gi|400402|sp|P13595|NCA1_MOUSE Neural cell adhesion molecule 1, ...   146   4e-33
gi|31323699|gb|AAP47136.1| sialoadhesin [Sus scrofa]                  146   4e-33
gi|37547126|ref|XP_056455.3| Melanoma associated gene [Homo sapi...   146   4e-33
gi|15030115|gb|AAH11310.1| Ncam1 protein [Mus musculus]               146   4e-33
gi|18450276|ref|NP_035005.1| neural cell adhesion molecule 1 [Mu...   146   4e-33
gi|47220346|emb|CAF98445.1| unnamed protein product [Tetraodon n...   146   5e-33
gi|400398|sp|P31836|NCA1_BOVIN Neural cell adhesion molecule 1, ...   145   7e-33
gi|27806019|ref|NP_776824.1| cell adhesion molecule, neural [Bos...   145   7e-33
gi|45642714|ref|NP_990790.1| smooth muscle myosin light chain ki...   145   7e-33
gi|7657359|ref|NP_055176.1| contactin 5 isoform long; neural adh...   145   7e-33
gi|28373129|ref|NP_780775.1| contactin 5 isoform short; neural a...   145   7e-33
gi|45552153|ref|NP_995599.1| CG32019-PD [Drosophila melanogaster...   145   9e-33
gi|14276867|gb|AAK58428.1| roundabout3 [Danio rerio]                  145   9e-33
gi|86236|pir||S01998 contactin precursor - chicken >gnl|BL_ORD_I...   145   9e-33
gi|50728200|ref|XP_416029.1| PREDICTED: similar to neural cell r...   145   9e-33
gi|50754590|ref|XP_414434.1| PREDICTED: similar to cell adhesion...   145   9e-33
gi|47224415|emb|CAG08665.1| unnamed protein product [Tetraodon n...   145   1e-32
gi|1439613|gb|AAB04558.1| neural cell adhesion molecule CD56; N-...   144   2e-32
gi|17536619|ref|NP_497045.1| basement membrane proteoglycan (2O9...   144   2e-32
gi|28574712|ref|NP_722954.2| CG31774-PA [Drosophila melanogaster...   144   2e-32
gi|47227750|emb|CAG08913.1| unnamed protein product [Tetraodon n...   144   2e-32
gi|40788219|dbj|BAA20801.2| KIAA0343 [Homo sapiens]                   144   2e-32
gi|31236539|ref|XP_319431.1| ENSANGP00000002862 [Anopheles gambi...   144   2e-32
gi|72067|pir||IJRTNC neural cell adhesion molecule short domain ...   144   2e-32
gi|13928706|ref|NP_113709.1| neural cell adhesion molecule 1; ce...   144   2e-32
gi|41281937|ref|NP_851996.1| neural cell adhesion molecule 1; an...   144   2e-32
gi|33519481|ref|NP_004531.2| neural cell adhesion molecule 2 pre...   144   3e-32
gi|24647696|ref|NP_732242.1| CG31190-PA [Drosophila melanogaster...   144   3e-32
gi|1708635|gb|AAC47451.1| neuroglian                                  143   3e-32
gi|459710|gb|AAB59957.1| neural cell adhesion molecule                143   3e-32
gi|459711|gb|AAB59959.1| neural cell adhesion molecule                143   3e-32
gi|2804782|gb|AAC38849.1| roundabout 1 [Drosophila melanogaster]      143   3e-32
gi|279680|pir||IJCHNL neural cell adhesion molecule long domain ...   143   3e-32
gi|2851523|sp|P13590|NCA1_CHICK Neural cell adhesion molecule 1,...   143   3e-32
gi|41054217|ref|NP_956098.1| contactin 5; wu:fi09g01 [Danio reri...   143   3e-32
gi|35010|emb|CAA42508.1| Neural cell adhesion molecule L1 [Homo ...   143   5e-32
gi|50777737|ref|XP_427362.1| PREDICTED: similar to basement memb...   143   5e-32
gi|47227826|emb|CAG08989.1| unnamed protein product [Tetraodon n...   143   5e-32
gi|24580861|ref|NP_536792.2| CG5481-PA [Drosophila melanogaster]...   142   8e-32
gi|50758795|ref|XP_417421.1| PREDICTED: similar to mKIAA0230 pro...   142   8e-32
gi|11907988|gb|AAG41425.1| roundabout 2 [Drosophila melanogaster]     142   8e-32
gi|50729836|ref|XP_416673.1| PREDICTED: similar to roundabout ho...   142   1e-31
gi|39596592|emb|CAE63211.1| Hypothetical protein CBG07568 [Caeno...   142   1e-31
gi|39582691|emb|CAE65897.1| Hypothetical protein CBG11064 [Caeno...   141   1e-31
gi|45551150|ref|NP_726224.2| CG13521-PB [Drosophila melanogaster...   141   1e-31
gi|31210307|ref|XP_314120.1| ENSANGP00000010312 [Anopheles gambi...   141   1e-31
gi|17136778|ref|NP_476899.1| CG13521-PA [Drosophila melanogaster...   141   1e-31
gi|50738619|ref|XP_419328.1| PREDICTED: similar to kinase-like p...   141   2e-31
gi|20908094|tpg|DAA00021.1| TPA: TITIN [Drosophila melanogaster]      140   2e-31
gi|48097458|ref|XP_393788.1| similar to CG33141-PA [Apis mellifera]   140   2e-31
gi|34922043|sp|Q98902|CAML_FUGRU Neural cell adhesion molecule L...   140   3e-31
gi|3334268|sp|O15394|NCM2_HUMAN Neural cell adhesion molecule 2 ...   140   3e-31
gi|27894376|ref|NP_006605.2| cell adhesion molecule with homolog...   140   3e-31
gi|2190958|gb|AAB60937.1| neural cell adhesion molecule [Homo sa...   140   3e-31
gi|45382937|ref|NP_989943.1| FAR-2 protein [Gallus gallus] >gnl|...   140   3e-31
gi|47219380|emb|CAG01543.1| unnamed protein product [Tetraodon n...   140   3e-31
gi|48102162|ref|XP_395296.1| similar to Neuroglian precursor [Ap...   140   3e-31
gi|28573431|ref|NP_788355.1| CG7449-PB [Drosophila melanogaster]...   140   4e-31
gi|28573429|ref|NP_524702.3| CG7449-PA [Drosophila melanogaster]...   140   4e-31
gi|11079653|ref|NP_032504.2| L1 cell adhesion molecule [Mus musc...   140   4e-31
gi|211279|gb|AAA48632.1| cell adhesion molecule                       140   4e-31
gi|226133|prf||1411301A neural adhesion mol L1                        140   4e-31
gi|50728120|ref|XP_429293.1| PREDICTED: hypothetical protein XP_...   140   4e-31
gi|6625978|gb|AAF19446.1| hibris [Drosophila melanogaster]            139   5e-31
gi|21758974|dbj|BAC05429.1| unnamed protein product [Homo sapiens]    139   5e-31
gi|41281389|ref|NP_005001.2| neuronal cell adhesion molecule; Br...   139   5e-31
gi|47213522|emb|CAF96065.1| unnamed protein product [Tetraodon n...   139   5e-31
gi|345685|pir||A43425 Bravo/Nr-CAM cell adhesion molecule L1 hom...   139   7e-31
gi|45383994|ref|NP_990597.1| Nr-CAM protein [Gallus gallus] >gnl...   139   9e-31
gi|47228828|emb|CAG07560.1| unnamed protein product [Tetraodon n...   139   9e-31
gi|47225700|emb|CAG08043.1| unnamed protein product [Tetraodon n...   139   9e-31
gi|462740|sp|P35331|NRCA_CHICK Neuronal cell adhesion molecule p...   139   9e-31
gi|29789453|ref|NP_795904.2| neuronal cell adhesion molecule [Mu...   138   1e-30
gi|31236138|ref|XP_319362.1| ENSANGP00000006165 [Anopheles gambi...   138   1e-30
gi|38372441|sp|Q810U4|NRCA_MOUSE Neuronal cell adhesion molecule...   138   1e-30
gi|48095518|ref|XP_394463.1| similar to CG12676-PA [Apis mellifera]   138   1e-30
gi|8134651|sp|Q91048|PTK7_CHICK Tyrosine-protein kinase-like 7 p...   138   1e-30
gi|21391898|gb|AAM48303.1| AT03867p [Drosophila melanogaster]         138   1e-30
gi|24580839|ref|NP_608592.2| CG5423-PA [Drosophila melanogaster]...   137   2e-30
gi|11907990|gb|AAG41426.1| roundabout 3 [Drosophila melanogaster]     137   2e-30
gi|41137114|ref|XP_039627.9| contactin 3 (plasmacytoma associate...   137   2e-30
gi|7441747|pir||JE0100 neural cell adhesion molecule 2 - African...   137   2e-30
gi|16758746|ref|NP_446331.1| contactin 4; axonal-associated cell...   137   3e-30
gi|48094384|ref|XP_394162.1| similar to MGC68806 protein [Apis m...   137   3e-30
gi|28972161|dbj|BAC65534.1| mKIAA0343 protein [Mus musculus]          137   3e-30
gi|6651057|gb|AAF22153.1| neural cell adhesion molecule L1 [Mus ...   137   3e-30
gi|547997|sp|P36335|NCA2_XENLA Neural cell adhesion molecule 2, ...   136   4e-30
gi|34535186|dbj|BAC87234.1| unnamed protein product [Homo sapiens]    136   4e-30
gi|27370508|ref|NP_766592.1| contactin 4; axonal-associated cell...   136   4e-30
gi|26006253|dbj|BAC41469.1| mKIAA1132 protein [Mus musculus]          136   6e-30
gi|6651381|gb|AAF22283.1| NgCAM-related related cell adhesion mo...   135   7e-30
gi|33112413|sp|Q92823|NRCA_HUMAN Neuronal cell adhesion molecule...   135   7e-30
gi|2511666|emb|CAA04507.1| NrCAM protein [Homo sapiens]               135   7e-30
gi|6651380|gb|AAF22282.1| NgCAM-related related cell adhesion mo...   135   7e-30
gi|50760107|ref|XP_425794.1| PREDICTED: similar to transmembrane...   135   1e-29
gi|15425681|dbj|BAB64297.1| I-connectin [Procambarus clarkii]         135   1e-29
gi|26333963|dbj|BAC30699.1| unnamed protein product [Mus musculus]    135   1e-29
gi|32822812|gb|AAH55053.1| C130076O07Rik protein [Mus musculus]       134   2e-29
gi|18859063|ref|NP_571277.1| neural cell adhesion molecule 1; ce...   134   2e-29
gi|6680936|ref|NP_031723.1| cell adhesion molecule with homology...   134   2e-29
gi|28373122|ref|NP_783200.1| contactin 4 isoform a precursor; ax...   134   2e-29
gi|7441746|pir||JE0099 neural cell adhesion molecule 1 - African...   134   2e-29
gi|21428708|gb|AAM50014.1| SD04592p [Drosophila melanogaster]         134   3e-29
gi|50729870|ref|XP_425540.1| PREDICTED: similar to neural cell a...   134   3e-29
gi|127855|sp|P16170|NCA1_XENLA Neural cell adhesion molecule 1, ...   134   3e-29
gi|27652188|gb|AAO17583.1| L1 cell adhesion molecule [Homo sapie...   134   3e-29
gi|47213409|emb|CAF93208.1| unnamed protein product [Tetraodon n...   134   3e-29
gi|36143027|gb|AAQ85080.1| neural adhesion molecule L1.2 [Danio ...   134   3e-29
gi|6755584|ref|NP_035556.1| sialoadhesin [Mus musculus] >gnl|BL_...   133   4e-29
gi|42821116|ref|NP_981954.1| neural cell adhesion molecule 2; fa...   133   4e-29
gi|50760226|ref|XP_425812.1| PREDICTED: similar to neural cell a...   133   4e-29
gi|27652282|gb|AAO17630.1| L1 cell adhesion molecule [Pan troglo...   133   4e-29
gi|42528323|gb|AAS18426.1| fasciclin II GPI-linked protein isofo...   133   4e-29
gi|28558739|ref|NP_726608.2| CG32019-PA [Drosophila melanogaster...   133   4e-29
gi|25147920|ref|NP_741748.1| sensory AXon guidance SAX-3, rounda...   133   5e-29
gi|21240773|gb|AAB52657.2| Sensory axon guidance protein 3, isof...   133   5e-29
gi|8393820|ref|NP_059041.1| neural cell adhesion molecule L1 [Ra...   132   6e-29
gi|19924211|ref|NP_446361.1| neurofascin [Rattus norvegicus] >gn...   132   6e-29
gi|20143918|ref|NP_597676.1| titin isoform novex-1; connectin; C...   132   6e-29
gi|20455467|sp|Q05695|CAML_RAT Neural cell adhesion molecule L1 ...   132   6e-29
gi|17066108|emb|CAD12459.1| Titin Novex-1 Isoform [Homo sapiens]      132   6e-29
gi|7959253|dbj|BAA96020.1| KIAA1496 protein [Homo sapiens]            132   8e-29
gi|47224417|emb|CAG08667.1| unnamed protein product [Tetraodon n...   132   8e-29
gi|21752491|dbj|BAC04201.1| unnamed protein product [Homo sapiens]    132   8e-29
gi|1842427|gb|AAB47753.1| ankyrin binding cell adhesion molecule...   132   8e-29
gi|6679207|ref|NP_032805.1| contactin 3; plasmacytoma-associated...   132   8e-29
gi|14276863|gb|AAK58426.1| roundabout1 [Danio rerio]                  132   1e-28
gi|3334269|sp|O35136|NCM2_MOUSE Neural cell adhesion molecule 2 ...   132   1e-28
gi|38014810|gb|AAH60500.1| MGC68806 protein [Xenopus laevis]          132   1e-28
gi|6754920|ref|NP_035084.1| neural cell adhesion molecule 2; olf...   132   1e-28
gi|6919968|sp|Q62230|SN_MOUSE Sialoadhesin precursor (Sialic aci...   131   1e-28
gi|30425042|ref|NP_780377.1| PTK7 protein tyrosine kinase 7 [Mus...   131   1e-28
gi|557250|emb|CAA85268.1| sialoadhesin [Mus musculus]                 131   1e-28
gi|38372401|sp|P97686|NRCA_RAT Neuronal cell adhesion molecule p...   131   2e-28
gi|1842431|gb|AAB47755.1| ankyrin binding cell adhesion molecule...   131   2e-28
gi|49119255|gb|AAH73282.1| Unknown (protein for MGC:80658) [Xeno...   131   2e-28
gi|39597744|emb|CAE68436.1| Hypothetical protein CBG14221 [Caeno...   130   2e-28
gi|20521151|dbj|BAA34476.2| KIAA0756 protein [Homo sapiens]           130   2e-28
gi|42655823|ref|XP_046808.11| neurofascin [Homo sapiens]              130   2e-28
gi|1842429|gb|AAB47754.1| ankyrin binding cell adhesion molecule...   130   2e-28
gi|38372284|sp|O94856|NFAS_HUMAN Neurofascin precursor                130   2e-28
gi|38372259|sp|P97685|NFAS_RAT Neurofascin precursor                  130   2e-28
gi|283899|pir||S26180 neurofascin - chicken >gnl|BL_ORD_ID|14641...   130   3e-28
gi|50760291|ref|XP_417958.1| PREDICTED: similar to neurofascin [...   130   3e-28
gi|34535397|dbj|BAC87305.1| unnamed protein product [Homo sapiens]    130   3e-28
gi|38372283|sp|O42414|NFAS_CHICK Neurofascin precursor >gnl|BL_O...   130   3e-28
gi|11277081|pir||T43027 neural cell adhesion molecule L1 - goldf...   130   3e-28
gi|38089779|ref|XP_146674.3| similar to immunoglobulin superfami...   130   4e-28
gi|29134779|dbj|BAC66140.1| projectin [Procambarus clarkii]           130   4e-28
gi|45383896|ref|NP_989436.1| sidekick 1 [Gallus gallus] >gnl|BL_...   129   5e-28
gi|31201737|ref|XP_309816.1| ENSANGP00000018216 [Anopheles gambi...   129   5e-28
gi|47226301|emb|CAG09269.1| unnamed protein product [Tetraodon n...   129   5e-28
gi|37360078|dbj|BAC98017.1| mKIAA0756 protein [Mus musculus]          129   5e-28
gi|41222723|ref|XP_373319.1| similar to hemicentin [Homo sapiens]     129   7e-28
gi|50752572|ref|XP_422837.1| PREDICTED: similar to immunoglobuli...   129   7e-28
gi|18859065|ref|NP_571905.1| neural cell adhesion molecule 2 [Da...   129   7e-28
gi|21104338|emb|CAC85752.1| obscurin [Homo sapiens]                   129   7e-28
gi|35215309|ref|NP_874385.1| neurofascin [Mus musculus] >gnl|BL_...   129   9e-28
gi|34865157|ref|XP_343057.1| neuron-glia-CAM-related cell adhesi...   128   1e-27
gi|37539895|ref|XP_351855.1| similar to cDNA sequence BC034076 [...   128   1e-27
gi|47058952|ref|NP_037282.1| neuron-glia-CAM-related cell adhesi...   128   1e-27
gi|46369969|gb|AAS89820.1| neuronal cell adhesion molecule long ...   128   1e-27
gi|46369973|gb|AAS89822.1| neuronal cell adhesion molecule long ...   128   1e-27
gi|46369975|gb|AAS89823.1| neuronal cell adhesion molecule long ...   128   1e-27
gi|46369971|gb|AAS89821.1| neuronal cell adhesion molecule long ...   128   1e-27
gi|46369977|gb|AAS89824.1| neuronal cell adhesion molecule long ...   128   1e-27
gi|47938093|gb|AAH71557.1| PTK7 protein tyrosine kinase 7, isofo...   128   2e-27
gi|2136061|pir||JC4593 protein-tyrosine kinase-related receptor ...   128   2e-27
gi|15826840|ref|NP_002812.2| PTK7 protein tyrosine kinase 7 isof...   128   2e-27
gi|31199227|ref|XP_308561.1| ENSANGP00000009569 [Anopheles gambi...   128   2e-27
gi|20143914|ref|NP_003310.2| titin isoform N2-B; connectin; CMH9...   128   2e-27
gi|34867440|ref|XP_213677.2| roundabout (axon guidance receptor,...   128   2e-27
gi|27886609|ref|NP_690622.1| PTK7 protein tyrosine kinase 7 isof...   128   2e-27
gi|114735|sp|P28685|AXO1_CHICK Contactin 2 precursor (Axonin-1) ...   127   2e-27
gi|50760293|ref|XP_417959.1| PREDICTED: similar to axonin-1 [Gal...   127   2e-27
gi|31213065|ref|XP_315476.1| ENSANGP00000021235 [Anopheles gambi...   127   2e-27
gi|47223898|emb|CAG06075.1| unnamed protein product [Tetraodon n...   127   3e-27
gi|1621283|gb|AAC50765.1| hBRAVO/Nr-CAM precursor                     127   3e-27
gi|50511265|dbj|BAD32618.1| mKIAA3024 protein [Mus musculus]          127   3e-27
gi|18859067|ref|NP_571906.1| neural cell adhesion molecule 3 [Da...   127   3e-27
gi|48107961|ref|XP_396192.1| similar to roundabout 1 [Apis melli...   127   3e-27
gi|17066104|emb|CAD12455.1| N2B-Titin Isoform [Homo sapiens]          127   3e-27
gi|34860609|ref|XP_235959.2| similar to immunoglobulin superfami...   127   3e-27
gi|49117906|gb|AAH72835.1| Unknown (protein for MGC:80200) [Xeno...   126   4e-27
gi|19852056|gb|AAL99983.1| Down syndrome cell adhesion molecule-...   126   4e-27
gi|6981246|ref|NP_037357.1| contactin 6; neural adhesion molecul...   126   4e-27
gi|47940323|gb|AAH72368.1| MGC84491 protein [Xenopus laevis]          126   4e-27
gi|20143922|ref|NP_597681.1| titin isoform novex-2; connectin; C...   126   6e-27
gi|47216683|emb|CAG05180.1| unnamed protein product [Tetraodon n...   125   8e-27
gi|39592554|emb|CAE63631.1| Hypothetical protein CBG08127 [Caeno...   125   8e-27
gi|2136280|pir||I38344 titin, cardiac muscle [validated] - human      125   8e-27
gi|1212992|emb|CAA62188.1| titin [Homo sapiens]                       125   8e-27
gi|11276093|ref|NP_062179.1| FMS-like tyrosine kinase 1; Fms-rel...   125   8e-27
gi|7657361|ref|NP_055276.1| contactin 6; neural adhesion molecul...   125   8e-27
gi|47227360|emb|CAF96909.1| unnamed protein product [Tetraodon n...   125   1e-26
gi|32880201|ref|NP_689957.2| sidekick homolog 1 [Homo sapiens] >...   125   1e-26
gi|6012063|emb|CAB57301.1| neural cell adhesion molecule L1 [Mus...   124   2e-26
gi|40254254|ref|NP_766388.2| sidekick 2 [Mus musculus] >gnl|BL_O...   124   2e-26
gi|47223830|emb|CAF98600.1| unnamed protein product [Tetraodon n...   124   2e-26
gi|26335725|dbj|BAC31563.1| unnamed protein product [Mus musculus]    124   2e-26
gi|7209914|dbj|BAA92367.1| neural recognition molecule NB-3 [Mus...   124   2e-26
gi|31980846|ref|NP_059079.2| contactin 6; neural recognition mol...   124   2e-26
gi|34853550|ref|XP_342409.1| similar to D030068H01 protein [Ratt...   124   3e-26
gi|4827022|ref|NP_005067.1| contactin 2 precursor; transiently-e...   124   3e-26
gi|444868|prf||1908253A TAG-1 protein (axonin 1)                      124   3e-26
gi|28571083|ref|NP_599142.3| CG5227-PD [Drosophila melanogaster]...   123   4e-26
gi|14041957|dbj|BAB55049.1| unnamed protein product [Homo sapiens]    123   4e-26
gi|6981632|ref|NP_037016.1| contactin 2; transient axonal glycop...   123   4e-26
gi|45549089|ref|NP_477290.4| CG5227-PC [Drosophila melanogaster]...   123   4e-26
gi|6691810|emb|CAB65848.1| EG:BACR19J1.1 [Drosophila melanogaster]    123   5e-26
gi|26342350|dbj|BAC34837.1| unnamed protein product [Mus musculus]    123   5e-26
gi|50729838|ref|XP_416674.1| PREDICTED: similar to roundabout ho...   122   6e-26
gi|414791|emb|CAA79696.1| contactin [Homo sapiens]                    122   8e-26
gi|28373117|ref|NP_001834.2| contactin 1 isoform 1 precursor; gl...   122   8e-26
gi|462073|sp|P22648|FAS2_SCHAM Fasciclin II precursor (FAS II) >...   122   8e-26
gi|28373119|ref|NP_778203.1| contactin 1 isoform 2 precursor; gl...   122   8e-26
gi|48138212|ref|XP_396867.1| similar to CG12676-PA [Apis mellifera]   122   8e-26
gi|8134650|sp|Q13308|PTK7_HUMAN Tyrosine-protein kinase-like 7 p...   122   8e-26
gi|31201555|ref|XP_309725.1| ENSANGP00000012618 [Anopheles gambi...   122   1e-25
gi|22477205|gb|AAH36569.1| CNTN1 protein [Homo sapiens]               122   1e-25
gi|31208805|ref|XP_313369.1| ENSANGP00000011303 [Anopheles gambi...   122   1e-25
gi|22902130|ref|NP_690621.1| PTK7 protein tyrosine kinase 7 isof...   122   1e-25
gi|31982241|ref|NP_808317.2| cDNA sequence BC034076 [Mus musculu...   122   1e-25
gi|44890693|gb|AAH66864.1| Cntn1 protein [Mus musculus]               121   1e-25
gi|6680954|ref|NP_031753.1| contactin 1 [Mus musculus] >gnl|BL_O...   121   1e-25
gi|24581578|ref|NP_523469.2| CG12676-PA [Drosophila melanogaster...   121   1e-25
gi|12597263|gb|AAG60004.1| echinoid [Drosophila melanogaster]         121   1e-25
gi|47211487|emb|CAF95092.1| unnamed protein product [Tetraodon n...   120   1e-25
gi|50750381|ref|XP_421979.1| PREDICTED: similar to connectin/tit...   121   2e-25
gi|47222083|emb|CAG12109.1| unnamed protein product [Tetraodon n...   120   2e-25
gi|26326581|dbj|BAC27034.1| unnamed protein product [Mus musculus]    120   2e-25
gi|41946117|gb|AAH66106.1| Cntn2 protein [Mus musculus]               120   2e-25
gi|31204473|ref|XP_311185.1| ENSANGP00000001527 [Anopheles gambi...   120   3e-25
gi|15425683|dbj|BAB64298.1| Kettin [Procambarus clarkii]              120   3e-25
gi|45580802|ref|NP_995962.1| CG33484-PA [Drosophila melanogaster...   120   4e-25
gi|41281630|ref|NP_571458.1| neural adhesion molecule L1.1 [Dani...   120   4e-25
gi|31337510|emb|CAD66435.1| zormin [Drosophila melanogaster]          120   4e-25
gi|31204619|ref|XP_311258.1| ENSANGP00000001591 [Anopheles gambi...   120   4e-25
gi|1095168|prf||2107324A neural adhesion molecule F3                  120   4e-25
gi|47228707|emb|CAG07439.1| unnamed protein product [Tetraodon n...   120   4e-25
gi|1430860|emb|CAA67504.1| brain-derived immunoglobulin superfam...   120   4e-25
gi|16923964|ref|NP_476459.1| contactin 1 [Rattus norvegicus] >gn...   119   5e-25
gi|48854852|ref|ZP_00309013.1| COG3210: Large exoproteins involv...   119   5e-25
gi|21757394|dbj|BAC05109.1| unnamed protein product [Homo sapiens]    119   7e-25
gi|42659643|ref|XP_290502.2| KIAA1030 protein [Homo sapiens]          119   7e-25
gi|1363280|pir||A57112 contactin precursor - rat                      119   9e-25
gi|47211486|emb|CAF95091.1| unnamed protein product [Tetraodon n...   119   9e-25
gi|47223365|emb|CAG04226.1| unnamed protein product [Tetraodon n...   119   9e-25
gi|3219157|dbj|BAA28780.1| contactin A [Xenopus laevis]               118   1e-24
gi|47522704|ref|NP_999056.1| vascular cell adhesion molecule [Su...   118   2e-24
gi|30725824|ref|NP_851300.1| contactin 1 [Danio rerio] >gnl|BL_O...   117   2e-24
gi|1199461|gb|AAB59281.1| vascular cell adhesion molecule             117   3e-24
gi|6679036|ref|NP_032710.1| neogenin [Mus musculus] >gnl|BL_ORD_...   117   3e-24
gi|47209404|emb|CAF90870.1| unnamed protein product [Tetraodon n...   117   3e-24
gi|38614294|gb|AAH60237.1| Sdk1 protein [Mus musculus]                117   3e-24
gi|15291623|gb|AAK93080.1| LD11008p [Drosophila melanogaster]         116   5e-24
gi|45552151|ref|NP_995598.1| CG32019-PC [Drosophila melanogaster...   116   5e-24
gi|4507875|ref|NP_001069.1| vascular cell adhesion molecule 1 is...   116   5e-24
gi|40714595|gb|AAR88555.1| LD10678p [Drosophila melanogaster]         116   5e-24
gi|37537817|sp|Q90478|CAM1_BRARE Neural cell adhesion molecule L...   116   6e-24
gi|47086301|ref|NP_998033.1| hypothetical protein zgc:64208 [Dan...   116   6e-24
gi|4336726|gb|AAD17919.1| fasciclin II transmembrane isoform [Ma...   116   6e-24
gi|32451629|gb|AAH54540.1| Neo1 protein [Mus musculus]                116   6e-24
gi|4336724|gb|AAD17918.1| fasciclin II GPI-linked isoform [Mandu...   116   6e-24
gi|7511705|pir||T18531 tractin - medicinal leech >gnl|BL_ORD_ID|...   116   6e-24
gi|47221015|emb|CAF98244.1| unnamed protein product [Tetraodon n...   116   6e-24
gi|1843425|dbj|BAA13100.1| contactin/F3/F11 [Xenopus laevis]          115   1e-23
gi|27805871|ref|NP_776705.1| contactin 1 [Bos taurus] >gnl|BL_OR...   114   2e-23
gi|18252625|gb|AAL66362.1| brother of CDO [Danio rerio]               114   2e-23
gi|50729608|ref|XP_416581.1| PREDICTED: similar to brother of CD...   114   2e-23
gi|10720132|sp|P97603|NEO1_RAT Neogenin precursor >gnl|BL_ORD_ID...   114   2e-23
gi|34863768|ref|XP_343403.1| neogenin [Rattus norvegicus]             114   2e-23
gi|40538872|ref|NP_954890.1| MAM domain containing glycosylphosp...   114   2e-23
gi|2078518|gb|AAC51287.1| neogenin [Homo sapiens]                     114   3e-23
gi|28894262|gb|AAO52742.1| adhesion molecule VCAM-1 [Oryctolagus...   114   3e-23
gi|46275816|ref|NP_996893.1| MAM domain containing 1; MAM domain...   114   3e-23
gi|37181775|gb|AAQ88694.1| BOC [Homo sapiens]                         113   4e-23
gi|15147240|ref|NP_150279.1| brother of CDO [Homo sapiens] >gnl|...   113   4e-23
gi|50754592|ref|XP_414435.1| PREDICTED: similar to Contactin 4, ...   113   5e-23
gi|47227363|emb|CAF96912.1| unnamed protein product [Tetraodon n...   113   5e-23
gi|30725726|ref|NP_849215.1| expressed sequence AW822216 [Mus mu...   113   5e-23
gi|4505375|ref|NP_002490.1| neogenin homolog 1; neogenin (chicke...   113   5e-23
gi|37549383|ref|XP_051017.3| KIAA0657 protein [Homo sapiens]          112   7e-23
gi|21104330|emb|CAC85747.1| obscurin [Homo sapiens]                   112   9e-23
gi|46403175|sp|Q7Z553|MDC1_HUMAN MAM domain containing protein 1...   112   9e-23
gi|6681139|ref|NP_031857.1| deleted in colorectal carcinoma [Mus...   112   1e-22
gi|37181356|gb|AAQ88492.1| MAM-domain protein [Homo sapiens]          112   1e-22
gi|20177992|sp|Q9R044|NPHN_RAT Nephrin precursor (Renal glomerul...   112   1e-22
gi|9651182|gb|AAF91086.1| nephrin [Rattus norvegicus]                 112   1e-22
gi|48133425|ref|XP_393339.1| similar to EG:EG0007.3 [Apis mellif...   112   1e-22
gi|12018318|ref|NP_072150.1| nephrin [Rattus norvegicus] >gnl|BL...   112   1e-22
gi|2275262|gb|AAC47655.1| leechCAM [Hirudo medicinalis]               111   1e-22
gi|29289929|gb|AAL92552.1| neogenin [Danio rerio]                     110   3e-22
gi|22003417|gb|AAM88671.1| neogenin [Danio rerio]                     110   3e-22
gi|6978755|ref|NP_036973.1| deleted in colorectal carcinoma; Del...   110   3e-22
gi|27545187|ref|NP_775325.1| neogenin 1 [Danio rerio] >gnl|BL_OR...   110   3e-22
gi|31231678|ref|XP_318566.1| ENSANGP00000019615 [Anopheles gambi...   110   3e-22
gi|2134173|pir||I51669 tumor suppressor - African clawed frog >g...   110   3e-22
gi|45645161|gb|AAS73243.1| neuronal cell adhesion molecule [Bos ...   110   3e-22
gi|34855795|ref|XP_218523.2| similar to B lymphocyte cell adhesi...   110   4e-22
gi|26006461|ref|NP_115920.1| kin of IRRE like 3 [Homo sapiens] >...   110   4e-22
gi|37182605|gb|AAQ89103.1| NEPH2 [Homo sapiens]                       110   4e-22
gi|47222973|emb|CAF99129.1| unnamed protein product [Tetraodon n...   110   4e-22
gi|31236143|ref|XP_319363.1| ENSANGP00000006166 [Anopheles gambi...   110   4e-22
gi|14017951|dbj|BAB47496.1| KIAA1867 protein [Homo sapiens]           110   4e-22
gi|19584322|emb|CAD28458.1| hypothetical protein [Homo sapiens]       109   6e-22
gi|34857640|ref|XP_346712.1| hypothetical protein XP_346711 [Rat...   109   6e-22
gi|9506949|ref|NP_062202.1| contactin 3; Plasmacytoma-associated...   109   6e-22
gi|1480842|gb|AAB05806.1| cell adhesion molecule n-cam [Danio re...   109   7e-22
gi|38648725|gb|AAH63072.1| Kirrel3 protein [Mus musculus]             109   7e-22
gi|26337297|dbj|BAC32333.1| unnamed protein product [Mus musculus]    109   7e-22
gi|26329731|dbj|BAC28604.1| unnamed protein product [Mus musculu...   109   7e-22
gi|45383103|ref|NP_989869.1| sidekick 2 [Gallus gallus] >gnl|BL_...   109   7e-22
gi|29824425|ref|NP_080600.1| membrane protein mKirre; X kin of I...   109   7e-22
gi|34864224|ref|XP_236346.2| similar to putative neuronal cell a...   109   7e-22
gi|4885175|ref|NP_005206.1| deleted in colorectal carcinoma [Hom...   108   1e-21
gi|26341680|dbj|BAC34502.1| unnamed protein product [Mus musculu...   108   1e-21
gi|47229254|emb|CAG04006.1| unnamed protein product [Tetraodon n...   108   1e-21
gi|6679571|ref|NP_033014.1| putative neuronal cell adhesion mole...   108   1e-21
gi|47213162|emb|CAG06233.1| unnamed protein product [Tetraodon n...   108   1e-21
gi|181493|gb|AAA35751.1| colorectal tumor suppressor (put.); put...   108   1e-21
gi|14669609|gb|AAK71998.1| brother of CDO [Xenopus laevis]            108   1e-21
gi|103156|pir||B41054 fasciclin II PI-linked splice form precurs...   108   1e-21
gi|17933556|ref|NP_525066.1| CG3665-PA [Drosophila melanogaster]...   108   1e-21
gi|4185886|emb|CAA21825.1| EG:EG0007.3 [Drosophila melanogaster]      108   1e-21
gi|4185887|emb|CAA21826.1| EG:EG0007.3 [Drosophila melanogaster]      108   1e-21
gi|24639639|ref|NP_726912.1| CG3665-PC [Drosophila melanogaster]...   108   1e-21


>gi|7499207|pir||T20992 hypothetical protein F15G9.4a - Caenorhabditis
            elegans
 gi|3875955|emb|CAA87335.1| C. elegans HIM-4 protein (corresponding
            sequence F15G9.4a) [Caenorhabditis elegans]
 gi|3879657|emb|CAA87344.1| C. elegans HIM-4 protein (corresponding
            sequence F15G9.4a) [Caenorhabditis elegans]
          Length = 5175

 Score = 3104 bits (8047), Expect = 0.0
 Identities = 1524/1578 (96%), Positives = 1524/1578 (96%)
 Frame = +2

Query: 2    ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH 181
            ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH
Sbjct: 3598 ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH 3657

Query: 182  DFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDL 361
            DFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDL
Sbjct: 3658 DFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDL 3717

Query: 362  TDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQP 541
            TDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQP
Sbjct: 3718 TDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQP 3777

Query: 542  QVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWS 721
            QVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWS
Sbjct: 3778 QVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWS 3837

Query: 722  CVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGS 901
            CVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGS
Sbjct: 3838 CVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGS 3897

Query: 902  LIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDG 1081
            LIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDG
Sbjct: 3898 LIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDG 3957

Query: 1082 IDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLS 1261
            IDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLS
Sbjct: 3958 IDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLS 4017

Query: 1262 DKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVIEGELAVIECLVEGYPAPQVSW 1441
            DKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVIEGELAVIECLVEGYPAPQVSW
Sbjct: 4018 DKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVIEGELAVIECLVEGYPAPQVSW 4077

Query: 1442 LRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPK 1621
            LRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPK
Sbjct: 4078 LRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPK 4137

Query: 1622 IITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKA 1801
            IITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKA
Sbjct: 4138 IITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKA 4197

Query: 1802 EERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCXXXXXXXX 1981
            EERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKC
Sbjct: 4198 EERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCEIESESSE 4257

Query: 1982 XXXXKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVA 2161
                KNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVA
Sbjct: 4258 FSWSKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVA 4317

Query: 2162 PKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATTKKKSVIFS 2341
            PKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATTKKKSVIFS
Sbjct: 4318 PKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATTKKKSVIFS 4377

Query: 2342 SISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFLSCNATGIP 2521
            SISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFLSCNATGIP
Sbjct: 4378 SISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFLSCNATGIP 4437

Query: 2522 EPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVN 2701
            EPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVN
Sbjct: 4438 EPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVN 4497

Query: 2702 KPSDRPAPIWVECDEKGKPKKTEYMIDRGDTPDDNPQLLPWKDVEDSSLNGSIAYRCMPG 2881
            KPSDRPAPIWVECDEKGKPKKTEYMIDRGDTPDDNPQLLPWKDVEDSSLNGSIAYRCMPG
Sbjct: 4498 KPSDRPAPIWVECDEKGKPKKTEYMIDRGDTPDDNPQLLPWKDVEDSSLNGSIAYRCMPG 4557

Query: 2882 PRSSRTVLLHAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEI 3061
            PRSSRTVLLHAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEI
Sbjct: 4558 PRSSRTVLLHAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEI 4617

Query: 3062 AYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITCY 3241
            AYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITCY
Sbjct: 4618 AYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITCY 4677

Query: 3242 ERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRH 3421
            ERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRH
Sbjct: 4678 ERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRH 4737

Query: 3422 SIPHLTSAFEGVPEVKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIY 3601
            SIPHLTSAFEGVPEVKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIY
Sbjct: 4738 SIPHLTSAFEGVPEVKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIY 4797

Query: 3602 XXXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNVYGGSSRREAYKKENEDASXXX 3781
                        EKYDEGVYKCVASNSIGKAFDDTQLNVYGGSSRREAYKKENEDAS
Sbjct: 4798 VLPNNSLVLLNVEKYDEGVYKCVASNSIGKAFDDTQLNVYGGSSRREAYKKENEDASTTT 4857

Query: 3782 XXXXXXXXXXXXXXXXXXXXXXXXXXXAKQYPTDDYHEGSANDDGFGPTTQDSLFEFNPP 3961
                                       AKQYPTDDYHEGSANDDGFGPTTQDSLFEFNPP
Sbjct: 4858 ITTTSPTTTTTETPLTTTIIPALITLPAKQYPTDDYHEGSANDDGFGPTTQDSLFEFNPP 4917

Query: 3962 LHPEISVVNTDCAGTINENGDCVDKDGKTHNLKILTGENHCPEGFAMNPHTRICEDLDEC 4141
            LHPEISVVNTDCAGTINENGDCVDKDGKTHNLKILTGENHCPEGFAMNPHTRICEDLDEC
Sbjct: 4918 LHPEISVVNTDCAGTINENGDCVDKDGKTHNLKILTGENHCPEGFAMNPHTRICEDLDEC 4977

Query: 4142 AFYQPCDFECINYDGGFQCNCPLGYELAEEGCRDVNECESVRCEDGKACFNQLGGYECID 4321
            AFYQPCDFECINYDGGFQCNCPLGYELAEEGCRDVNECESVRCEDGKACFNQLGGYECID
Sbjct: 4978 AFYQPCDFECINYDGGFQCNCPLGYELAEEGCRDVNECESVRCEDGKACFNQLGGYECID 5037

Query: 4322 DPCPANYSLVDDRYCEPECENCTSTPIQVHMLAIPSGLPISHIATLTAYDKSGRVLNDTT 4501
            DPCPANYSLVDDRYCEPECENCTSTPIQVHMLAIPSGLPISHIATLTAYDKSGRVLNDTT
Sbjct: 5038 DPCPANYSLVDDRYCEPECENCTSTPIQVHMLAIPSGLPISHIATLTAYDKSGRVLNDTT 5097

Query: 4502 YAISDTGAPLARGRMTSGPFTIKAVKRGHAQVWTNRVLAAGDHHKVRVRAHSDHATNELH 4681
            YAISDTGAPLARGRMTSGPFTIKAVKRGHAQVWTNRVLAAGDHHKVRVRAHSDHATNELH
Sbjct: 5098 YAISDTGAPLARGRMTSGPFTIKAVKRGHAQVWTNRVLAAGDHHKVRVRAHSDHATNELH 5157

Query: 4682 APKETNFLVLINVGQYPF 4735
            APKETNFLVLINVGQYPF
Sbjct: 5158 APKETNFLVLINVGQYPF 5175



 Score =  424 bits (1089), Expect = e-116
 Identities = 351/1291 (27%), Positives = 547/1291 (42%), Gaps = 61/1291 (4%)
 Frame = +2

Query: 5    SGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHD 184
            +G P P +++ K+G  +N +D   I+     T  I+N Q   +GRYTC A N+ G++  D
Sbjct: 2878 TGTPPPTILFMKDGKRLNESDEVDII---GSTLVIDNPQKEVEGRYTCIAENKAGRSEKD 2934

Query: 185  FSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLT 364
              ++VL PP+         + + GD +TL CPI   ED +   + ++W++     DG L
Sbjct: 2935 MMVEVLLPPKLSKEWINVEV-QAGDPLTLECPI---EDTSG--VHITWSRQF-GKDGQLD 2987

Query: 365  DNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVI---DISRNDV 535
                 S D  KL I QA+ E+A  Y+CIA+N AG A   F+V + +PP I     S  ++
Sbjct: 2988 MRAQSSSDKSKLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEI 3047

Query: 536  QPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGK 715
                 +  P    C   G P P I W  +GK + +   +   +    L+I     +  G+
Sbjct: 3048 VADTTLEIP----CRTEGIPPPEISWFLDGKPILEMPGVTYKQGDLSLRIDNIKPNQEGR 3103

Query: 716  WSCVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKG 895
            ++CVAEN AG  E +  +++  PP V + S+      G   T+ C   GNP P + W K
Sbjct: 3104 YTCVAENKAGRAEQDTYVEISEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKD 3163

Query: 896  GSLIFDSPDGARISLKGARLDIPHLKKT---DVGDYTCQALNAAGTSEASVSVDVLVPPE 1066
            G      P  + +     +L   HL++T   D G YTC A N AG S+ +  V+VLVPP
Sbjct: 3164 G-----EPYTSDLLQFSTKLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEVLVPPR 3218

Query: 1067 INRDGIDMSPRLPAQQSLT--LQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQ 1240
            I     D    L  ++  T  + C   G+PVP + W  NG  +    P          +
Sbjct: 3219 IE----DEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEIEQFNP---------VLH 3265

Query: 1241 INNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVI-SNGGTKQVIEGELAVIECLVEG 1417
            I N + +D+G Y+C A N AG+    + +DV   P   ++  T  ++EGE A IEC ++G
Sbjct: 3266 IRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNIVEGESAKIECKIDG 3325

Query: 1418 YPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYT 1597
            +P P +SWL+ G      +  +     G  L I++A+  D G+Y C ATN  G ++Q +
Sbjct: 3326 HPKPTISWLKGGR--PFNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFK 3383

Query: 1598 LEVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGAD 1777
            + V   P I  +        +G +  L C V G P P ++W   G+D    ++ HTI  +
Sbjct: 3384 VNVYTKPYIDETIDQTPKAVAGGEIILKCPVLGNPTPTVTWK-RGDDAVPNDSRHTIVNN 3442

Query: 1778 GTLHIEK-AEERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIK 1954
              L I     E    Y C A N+AG  T  +  + I  P     G       E     +
Sbjct: 3443 YDLKINSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMD 3502

Query: 1955 CXXXXXXXXXXXXKNG-VPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNAT 2131
            C              G  P+   +    S D   I I   +LSD G+Y C A+N+AG +
Sbjct: 3503 CGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAKLSDGGKYICRASNEAGTSD 3562

Query: 2132 QKTNLNVGVAPK-----IMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTG 2296
                L + V PK     I+  P   V      + L C  SG+PQP + W K+   +  T
Sbjct: 3563 IDLILKILVPPKIDKSNIIGNPLAIVAR---TIYLECPISGIPQPDVIWTKNGMDINMTD 3619

Query: 2297 VDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEV-VPERMNVST 2473
                     ++    ++  +  G YTC A N       D  L V+ PPE  +
Sbjct: 3620 SRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIK 3679

Query: 2474 NPRQTVFLSCN---ATGIPEPV--ISWMRDSNIA---IQNNEKYQILGTTLAIRNVLPDD 2629
                T+ L+C    A  I + V  +SW +DS      + +N      G  L I     ++
Sbjct: 3680 REGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDGRKLTISQASLEN 3739

Query: 2630 DGFYHCIAKSDAGQKIATRKLIVNKP--------SDRP-----APIWVECDEKGKPKKTE 2770
             G Y CIA + AG+     K+ +  P          +P      P  + C   G P  +
Sbjct: 3740 AGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSI 3799

Query: 2771 YMIDRGD--TPDDNPQLLPWKDV-------EDSSLNGSIAYRCMPGPRSSRTVL-LHAAP 2920
              +  G   T D+N +++    V        D +   S       G +    VL +   P
Sbjct: 3800 KWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPP 3859

Query: 2921 QFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDS----KFEIAYSHLKVTL 3088
               VK  N   A+G  + L C+A+G P+P + WAK G LI DS    +  +  + L +
Sbjct: 3860 VVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGSLIFDSPDGARISLKGARLDIPH 3919

Query: 3089 NSTSDSGEYTCMAQNSVGSSTVSAFINV-------DNNILPTPKPSSNQKNVAVITCYER 3247
               +D G+YTC A N+ G+S  S  ++V        + I  +P+  + Q     + C  +
Sbjct: 3920 LKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQS--LTLQCLAQ 3977

Query: 3248 NQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRHSI 3427
             +   + + W  NG  +  +  GI   ++ + + ++  SL   D  +YTC   N
Sbjct: 3978 GKPVPQ-MRWTLNGTALTHSTPGITVASDSTFIQINNVSL--SDKGVYTCYAENVAGSDN 4034

Query: 3428 PHLTSAFEGVPEVKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLD--DDAIY 3601
                      P +      +V  G+  V++C V   P    V W +N  ++        Y
Sbjct: 4035 LMYNVDVVQAPVISNGGTKQVIEGELAVIECLVEGYP-APQVSWLRNGNRVETGVQGVRY 4093

Query: 3602 XXXXXXXXXXXXEKYDEGVYKCVASNSIGKA 3694
                           D G+Y C A+N  G A
Sbjct: 4094 VTDGRMLTIIEARSLDSGIYLCSATNEAGSA 4124



 Score =  412 bits (1060), Expect = e-113
 Identities = 347/1308 (26%), Positives = 555/1308 (41%), Gaps = 63/1308 (4%)
 Frame = +2

Query: 2    ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH 181
            ++G P P V W +NG +I          Q N    I N    D+G+Y+C A+N  G A
Sbjct: 3240 VTGRPVPYVTWKRNGKEIE---------QFNPVLHIRNATRADEGKYSCIASNEAGTAVA 3290

Query: 182  DFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDL 361
            DF +DV + P F+ H T   I  EG++  + C I            +SW K  R  +
Sbjct: 3291 DFLIDVFTKPTFETHETTFNIV-EGESAKIECKID-----GHPKPTISWLKGGRPFN--- 3341

Query: 362  TDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQP 541
             DN+ +S  G  L I +A   + GLYTC+A N  G++  +FKV + + P ID    D  P
Sbjct: 3342 MDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYID-ETIDQTP 3400

Query: 542  QVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWS 721
            +       I++C V G+P P++ W +    V +D    IV     L+I    ++ AG++S
Sbjct: 3401 KAVAGGEIILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNNYD-LKINSVTTEDAGQYS 3459

Query: 722  CVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKAL-GETITLFCNASGNPYPQLKWAKGG 898
            C+A N+AG        +V   P    K  N  + +  +TIT+ C  +  P P + W +G
Sbjct: 3460 CIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPSISWFRGD 3519

Query: 899  SLIF------DSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVP 1060
              ++       SPDG+ I++  A+L       +D G Y C+A N AGTS+  + + +LVP
Sbjct: 3520 KPVYLYDRYSISPDGSHITINKAKL-------SDGGKYICRASNEAGTSDIDLILKILVP 3572

Query: 1061 PEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQ 1240
            P+I++  I  +P     +++ L+C   G P P + WT NG  +  +   + +A ++
Sbjct: 3573 PKIDKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFG 3632

Query: 1241 INNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVI--EGELAVIECLVE 1414
            I NV ++D+G YTC A N  G  +  +++DV+  P     GT+  I  EG+   + C ++
Sbjct: 3633 IENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIK 3692

Query: 1415 -----GYPAPQVSWLRNGNRVETGV-QGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAG 1576
                       VSW ++   ++  +   V    DGR LTI +A   ++G+Y C A N AG
Sbjct: 3693 LAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDGRKLTISQASLENAGLYTCIALNRAG 3752

Query: 1577 SAQQAYTLEVLVSPKIITSTPGVLTP--SSGSKFSLPCAVRGYPDPIISWTLNGNDIKDG 1750
             A   + +E+L SP +I  +   + P  +      + CAV G+P P I W  NG ++ D
Sbjct: 3753 EASLEFKVEIL-SPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDD 3811

Query: 1751 ENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYING 1927
            EN   +     L I + +  H   + C A+NDAG   LE  +     P +S   +  I
Sbjct: 3812 ENIRIVEQGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKA 3871

Query: 1928 SEGTETVIKCXXXXXXXXXXXXKNGVPLLPSNNLIF-SEDYKLIKILSTRL-------SD 2083
               T T+               K G       +LIF S D   I +   RL       +D
Sbjct: 3872 LGETITLFCNASGNPYPQLKWAKGG-------SLIFDSPDGARISLKGARLDIPHLKKTD 3924

Query: 2084 QGEYSCTAANKAGNATQKTNLNVGVAPKIME-----RPRTQVVHKGDQVTLWCEASGVPQ 2248
             G+Y+C A N AG +    +++V V P+I        PR   +     +TL C A G P
Sbjct: 3925 VGDYTCQALNAAGTSEASVSVDVLVPPEINRDGIDMSPR---LPAQQSLTLQCLAQGKPV 3981

Query: 2249 PAITWYKDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIV 2428
            P + W  +   LT++    T  +    +  +++S S  GVYTC AEN VA ++  +  +
Sbjct: 3982 PQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAEN-VAGSDNLMYNVD 4040

Query: 2429 MIPPEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSN---IAIQNNEKYQILGTT 2599
            ++   V+           +   + C   G P P +SW+R+ N     +Q   +Y   G
Sbjct: 4041 VVQAPVISNGGTKQVIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQ-GVRYVTDGRM 4099

Query: 2600 LAIRNVLPDDDGFYHCIAKSDAG--------QKIATRKLIVNKPS----DRPAPIWVECD 2743
            L I      D G Y C A ++AG        + + + K+I + P        +   + C
Sbjct: 4100 LTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCA 4159

Query: 2744 EKGKPKK-TEYMIDRGDTPDDNPQLLPWKDVE---DSSLNGSIAYRCMPGPRSSRTVLLH 2911
             +G P     + ++  D  D         D     + +    + Y C      +    L
Sbjct: 4160 VRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKAEERHLIYEC-TAKNDAGADTLE 4218

Query: 2912 AAPQFIVKPKNTTA-------AIGAIVELRCSAAGPPHPTITWAKDGKLIEDSK---FEI 3061
               Q IV PK +T+       + G    ++C          +W+K+G  +  S    F
Sbjct: 4219 FPVQTIVAPKISTSGNRYINGSEGTETVIKCEIES-ESSEFSWSKNGVPLLPSNNLIFSE 4277

Query: 3062 AYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVD--NNILPTPKPSSNQKNVAVIT 3235
             Y  +K+     SD GEY+C A N  G++T    +NV     I+  P+     K   V
Sbjct: 4278 DYKLIKILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTL 4337

Query: 3236 CYERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRR 3415
              E +      +TW Y    +  N  G+          +  SS+      +YTCK  N
Sbjct: 4338 WCEASGVPQPAITW-YKDNELLTN-TGVDETATTKKKSVIFSSISPSQAGVYTCKAENWV 4395

Query: 3416 RHSIPHLTSAFEGVPE-VKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDD 3592
              +   +       PE V     V  N   +V L C  T  P    + W ++    + ++
Sbjct: 4396 ASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFLSCNATGIPEPV-ISWMRDSNIAIQNN 4454

Query: 3593 AIYXXXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNVYGGSSR 3736
              Y               D+G Y C+A +  G+     +L V   S R
Sbjct: 4455 EKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVNKPSDR 4502



 Score =  392 bits (1006), Expect = e-107
 Identities = 322/1299 (24%), Positives = 552/1299 (41%), Gaps = 59/1299 (4%)
 Frame = +2

Query: 2    ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH 181
            ++G P P V WTK+G  +    S  +L++  + F I + ++  +G Y C A N  G A
Sbjct: 2122 VTGKPNPVVTWTKDGRPVGDLKSVQVLSEGQQ-FKIVHAEIAHKGSYICMAKNDVGTAEI 2180

Query: 182  DFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDL 361
             F +D+++ P             +G  +   CPI   ++   Q++   W ++ + +D +
Sbjct: 2181 SFDVDIITRPMIQKGIKNIVTAIKGGALPFKCPIDDDKNFKGQII---WLRNYQPIDLEA 2237

Query: 362  TD-NVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQ 538
             D  +    + R+LTI   +  + G Y+C   N AGE S +FK  +L PP I +   D
Sbjct: 2238 EDARITRLSNDRRLTILNVTENDEGQYSCRVKNDAGENSFDFKATVLVPPTIIMLDKDKN 2297

Query: 539  PQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQV----LQILRTDSDH 706
                 +    + C  TG P P I W K+G+ +  +    I+  G++    L+I R
Sbjct: 2298 KTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGELNGNQLKITRIKEGD 2357

Query: 707  AGKWSCVAENDAGVKELEMVLDVFTPPVVS---VKSDNPIKALGETITLFCNASGNPYPQ 877
            AGK++C A+N AG  E ++ ++V T P +    + SD   +   E + + C     P  +
Sbjct: 2358 AGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQ-NERVVISCPVYARPPAK 2416

Query: 878  LKWAKGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLV 1057
            + W K G  +  S    + S  G +L +  L++TD   YTC A N AGT +    V +LV
Sbjct: 2417 ITWLKAGKPL-QSDKFVKTSANGQKLYLFKLRETDSSKYTCIATNEAGTDKRDFKVSMLV 2475

Query: 1058 PPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFI 1237
             P  +   I     + +    TL C A+G P P + W  +G A+  +   +   +    +
Sbjct: 2476 APSFDEPNIVRRITVNSGNPSTLHCPAKGSPSPTITWLKDGNAIEPNDRYVFFDAGRQ-L 2534

Query: 1238 QINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQV--IEGELAVIECLV 1411
            QI+    SD+G YTC A N  GSD+L   ++V+  PVI     + V  IEG  + + C
Sbjct: 2535 QISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIPPVIDGERREAVAVIEGFSSELFC-D 2593

Query: 1412 EGYPAPQVSWLRNGNRVET----GVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGS 1579
                   V W ++G  +      G   ++  + G+ ++ + AR  DSG Y C   N AG
Sbjct: 2594 SNSTGVDVEWQKDGLTINQDTLRGDSFIQIPSSGKKMSFLSARKSDSGRYTCIVRNPAGE 2653

Query: 1580 AQQAYTLEVLVSPKIIT--STPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGE 1753
            A++ +   V   P I    S+  + T        + C V G P P + W  +   ++
Sbjct: 2654 ARKLFDFAVNDPPSISDELSSANIQTIVPYYPVEINCVVSGSPHPKVYWLFDDKPLEPDS 2713

Query: 1754 NGHTIGADG-TLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYING 1927
              + +  +G TL I +++  H   Y C A+N+ G    +F V+    P         +
Sbjct: 2714 AAYELTNNGETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLVRVTAPPHFEKEREEVV-A 2772

Query: 1928 SEGTETVIKCXXXXXXXXXXXXKNGVPLLPSNNLIFSE---DYKLIKILSTRLSDQGEYS 2098
              G   ++ C             +       N +I S+   + K + + + +L D+G Y
Sbjct: 2773 RVGDTMLLTCNAESSVPLSSVYWHAHDESVQNGVITSKYAANEKTLNVTNIQLDDEGFYY 2832

Query: 2099 CTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNE 2278
            CTA N+AG   +   L V   P  +++ +   +  G ++TL C A+G P P I + KD +
Sbjct: 2833 CTAVNEAGITKKFFKLIVIETPYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGK 2892

Query: 2279 LLTNTG-VDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPE 2455
             L  +  VD   +T    ++  +      G YTC AEN    +E+D+ + V++PP++  E
Sbjct: 2893 RLNESDEVDIIGST----LVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKE 2948

Query: 2456 RMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILG--TTLAIRNVLPDD 2629
             +NV       + L C         I+W R      Q + + Q     + L I    P+D
Sbjct: 2949 WINVEVQAGDPLTLECPIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSKLYIMQATPED 3008

Query: 2630 DGFYHCIAKSDAGQKIATRKLIVNKPSD------------RPAPIWVECDEKG-KPKKTE 2770
               Y CIA +DAG   A  ++ VN P                  + + C  +G  P +
Sbjct: 3009 ADSYSCIAVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEIS 3068

Query: 2771 YMIDRGDTPDDNPQLLPWKD----VEDSSLNGSIAYRCMPGPRSSRT-----VLLHAAPQ 2923
            + +D     +         D    +++   N    Y C+   ++ R      V +   P+
Sbjct: 3069 WFLDGKPILEMPGVTYKQGDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEISEPPR 3128

Query: 2924 FIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGK-----LIEDSKFEIAYSHLKVTL 3088
             ++  +      G    +RC   G P P + W KDG+     L++ S  +++Y HL+ T
Sbjct: 3129 VVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKDGEPYTSDLLQFST-KLSYLHLRET- 3186

Query: 3089 NSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQK-------NVAVITCYER 3247
             + +D G YTC+A N  G S  +     D  +L  P+    ++       N  ++ C
Sbjct: 3187 -TLADGGTYTCIATNKAGESQTTT----DVEVLVPPRIEDEERVLQGKEGNTYMVHCQVT 3241

Query: 3248 NQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRHSI 3427
             +     +TW+ NG  + +    +H  N               D   Y+C   N    ++
Sbjct: 3242 GRPVPY-VTWKRNGKEIEQFNPVLHIRN-----------ATRADEGKYSCIASNEAGTAV 3289

Query: 3428 PHLTSAFEGVPEVKTIDKV-EVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIYX 3604
                      P  +T +    +  G+S  ++C++   P  T + W K  +    D+ I
Sbjct: 3290 ADFLIDVFTKPTFETHETTFNIVEGESAKIECKIDGHPKPT-ISWLKGGRPFNMDNIILS 3348

Query: 3605 XXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNVY 3721
                       +++D G+Y CVA+NS G +  D ++NVY
Sbjct: 3349 PRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVY 3387



 Score =  379 bits (973), Expect = e-103
 Identities = 346/1299 (26%), Positives = 550/1299 (41%), Gaps = 70/1299 (5%)
 Frame = +2

Query: 2    ISGIPQPDVIWTKNG--MDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKA 175
            +SG P P + W  +G  ++         L+ +  T   ++V V  +G Y C A ++G
Sbjct: 1573 VSGFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQEGNYHCVAQSKGNIL 1632

Query: 176  SHDFSLDVLSPPEFDIHGTQPTIKRE-GDTITLTCPIKLAEDIADQVMDVSWTKDSRALD 352
              D  L VL+ P   I G    ++   G  I+L+C ++   D  D+   V W+ +    +
Sbjct: 1633 DIDVELSVLAVP---IVGEDDNLEVFLGKDISLSCDLQTESD--DKTTFV-WSINGS--E 1684

Query: 353  GDLTDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRND 532
             D  DNV I  DG +L I+ A  EN G Y C   N AG+A     +++L PPV      +
Sbjct: 1685 SDRPDNVQIPSDGHRLYITDAKPENNGKYMCRVTNSAGKAERTLTLDVLEPPVFVEPVFE 1744

Query: 533  VQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAG 712
               ++  N P I++C VTG+P P++ W  +G +V  D++    E   +L+I +     A
Sbjct: 1745 ANQKLIGNNPIILQCQVTGNPKPTVIWKIDGNDV--DKSWLFDESLSLLRIEKLTGKSA- 1801

Query: 713  KWSCVAENDAGVKELEMVLDVFTPPVVSVKSD-NPIKALGETITLFCNASGNPYPQLKWA 889
            + SC AEN AG    +  +     P    + D   I    ETITL C  S   + Q+ W
Sbjct: 1802 QISCTAENKAGTASRDFFIQNIAAPTFKNEGDQETIFRESETITLDCPVSLGDF-QITWM 1860

Query: 890  KGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEI 1069
            K G  +  + + A  +L   RL I +  +     YTC A N AG       V V V P+I
Sbjct: 1861 KQGLPL--TENDAIFTLDNTRLTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQVLPKI 1918

Query: 1070 NRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINN 1249
                + +   +   + + L C A+G P P  +W  N   L      + V ++ T + +NN
Sbjct: 1919 KNAVVTL--EINEGEEIILTCDAEGNPTPTAKWDFNQGDLPKE--AVFVNNNHTVV-VNN 1973

Query: 1250 VSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVIEGELA---VIECLVEGY 1420
            V+    GVY CYA N  G      NV V   P   +G T+  +   L     +EC V+
Sbjct: 1974 VTKYHTGVYKCYATNKVGQAVKTINVHVRTKPRFESGLTESELTVNLTRSITLECDVDDA 2033

Query: 1421 PAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTL 1600
                +SW  NG        GV+ +  GR L I+ A++ D G Y C+ TNEAG A + + L
Sbjct: 2034 IGVGISWTVNGKPFLAETDGVQTLAGGRFLHIVSAKTDDHGSYACTVTNEAGVATKTFNL 2093

Query: 1601 EVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADG 1780
             V V P I+ +  G  T    +   LPC V G P+P+++WT +G  + D ++   +
Sbjct: 2094 FVQVPPTIV-NEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEGQ 2152

Query: 1781 TLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKC 1957
               I  AE  H   Y C AKND G   + F V  I  P I       +   +G     KC
Sbjct: 2153 QFKIVHAEIAHKGSYICMAKNDVGTAEISFDVDIITRPMIQKGIKNIVTAIKGGALPFKC 2212

Query: 1958 ---XXXXXXXXXXXXKNGVPL---LPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKA 2119
                           +N  P+        +    + + + IL+   +D+G+YSC   N A
Sbjct: 2213 PIDDDKNFKGQIIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTENDEGQYSCRVKNDA 2272

Query: 2120 GNATQKTNLNVGVAPKI--MERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNT 2293
            G  +      V V P I  +++ + +   +   VTL C A+G P+P ITW+KD E +
Sbjct: 2273 GENSFDFKATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIE 2332

Query: 2294 GVDE---TATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERM- 2461
             + +           +  + I    AG YTC+A+N   S E+D+++ V+  P++  + +
Sbjct: 2333 NIADIIPNGELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIP 2392

Query: 2462 -NVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNE--KYQILGTTLAIRNVLPDDD 2632
             +  +   + V +SC     P   I+W++ +   +Q+++  K    G  L +  +   D
Sbjct: 2393 SDYESQQNERVVISCPVYARPPAKITWLK-AGKPLQSDKFVKTSANGQKLYLFKLRETDS 2451

Query: 2633 GFYHCIAKSDAGQKIATRK--LIVNKPSDRP-----------APIWVECDEKGKPKKTEY 2773
              Y CIA ++AG      K  ++V    D P            P  + C  KG P  T
Sbjct: 2452 SKYTCIATNEAGTDKRDFKVSMLVAPSFDEPNIVRRITVNSGNPSTLHCPAKGSPSPTIT 2511

Query: 2774 MIDRGDTPDDNPQLL---PWKDVEDSSLNGSI--AYRCMP----GPRSSRTVLLHAAPQF 2926
             +  G+  + N + +     + ++ S   GS    Y C+     G       L    P
Sbjct: 2512 WLKDGNAIEPNDRYVFFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIPPV 2571

Query: 2927 IVKPKNTTAAI--GAIVELRCSAAGPPHPTITWAKDGKLIE------DSKFEIAYSHLKV 3082
            I   +    A+  G   EL C  +      + W KDG  I       DS  +I  S  K+
Sbjct: 2572 IDGERREAVAVIEGFSSELFCD-SNSTGVDVEWQKDGLTINQDTLRGDSFIQIPSSGKKM 2630

Query: 3083 TLNST--SDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITCY---ER 3247
            +  S   SDSG YTC+ +N  G +      +   N  P+     +  N+  I  Y   E
Sbjct: 2631 SFLSARKSDSGRYTCIVRNPAGEA--RKLFDFAVNDPPSISDELSSANIQTIVPYYPVEI 2688

Query: 3248 NQAYSRG----LTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNR- 3412
            N   S      + W ++  P+  + A     NNG  + +  S ++      YTC+ +N
Sbjct: 2689 NCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIVRSQVEHAG--TYTCEAQNNV 2746

Query: 3413 ---RRHSIPHLTSA--FEGVPEVKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQK 3577
               R+  +  +T+   FE     K  ++V    GD+++L C   S    + V W  +D+
Sbjct: 2747 GKARKDFLVRVTAPPHFE-----KEREEVVARVGDTMLLTCNAESSVPLSSVYWHAHDES 2801

Query: 3578 MLDD--DAIYXXXXXXXXXXXXEKYDEGVYKCVASNSIG 3688
            + +    + Y            +  DEG Y C A N  G
Sbjct: 2802 VQNGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAG 2840



 Score =  364 bits (935), Expect = 1e-98
 Identities = 332/1310 (25%), Positives = 538/1310 (40%), Gaps = 75/1310 (5%)
 Frame = +2

Query: 14   PQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSL 193
            P   + W K G  +  +D  V  + N +   +  ++ TD  +YTC ATN  G    DF +
Sbjct: 2413 PPAKITWLKAGKPLQ-SDKFVKTSANGQKLYLFKLRETDSSKYTCIATNEAGTDKRDFKV 2471

Query: 194  DVLSPPEFDIHGTQPTIKRE-----GDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGD 358
             +L  P FD    +P I R      G+  TL CP K           ++W KD  A++ +
Sbjct: 2472 SMLVAPSFD----EPNIVRRITVNSGNPSTLHCPAK-----GSPSPTITWLKDGNAIEPN 2522

Query: 359  LTDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQ 538
              D     D GR+L IS+    + G YTCIA N  G   LE  +E++ PPVID  R +
Sbjct: 2523 --DRYVFFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIPPVIDGERREAV 2580

Query: 539  PQV-AVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDD-----ENIRIVEQGQVLQILRTDS 700
              +   +         TG     ++W K+G  +  D       I+I   G+ +  L
Sbjct: 2581 AVIEGFSSELFCDSNSTG---VDVEWQKDGLTINQDTLRGDSFIQIPSSGKKMSFLSARK 2637

Query: 701  DHAGKWSCVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLF------CNASG 862
              +G+++C+  N AG         V  PP +S   D    A  +TI  +      C  SG
Sbjct: 2638 SDSGRYTCIVRNPAGEARKLFDFAVNDPPSIS---DELSSANIQTIVPYYPVEINCVVSG 2694

Query: 863  NPYPQLKWAKGGSLIFDS----PDGARISL--KGARLDIPHLKKTDVGDYTCQALNAAGT 1024
            +P+P++ W      +FD     PD A   L   G  L I   +    G YTC+A N  G
Sbjct: 2695 SPHPKVYW------LFDDKPLEPDSAAYELTNNGETLKIVRSQVEHAGTYTCEAQNNVGK 2748

Query: 1025 SEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGK-PVPQMRWTLNGTALTHST 1201
            +     V V  PP   ++  ++  R+    ++ L C A+   P+  + W  +  ++ +
Sbjct: 2749 ARKDFLVRVTAPPHFEKEREEVVARVG--DTMLLTCNAESSVPLSSVYWHAHDESVQNGV 2806

Query: 1202 PGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPV-ISNGGTKQVI 1378
                 A++   + + N+ L D+G Y C A N AG     + + V++ P  +       +I
Sbjct: 2807 ITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIETPYFLDQQKLYPII 2866

Query: 1379 EGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCS 1558
             G+   ++C   G P P + ++++G R+    + V  +  G  L I   +    G Y C
Sbjct: 2867 LGKRLTLDCSATGTPPPTILFMKDGKRLNESDE-VDII--GSTLVIDNPQKEVEGRYTCI 2923

Query: 1559 ATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLN-GN 1735
            A N+AG +++   +EVL+ PK+      V    +G   +L C +       I+W+   G
Sbjct: 2924 AENKAGRSEKDMMVEVLLPPKLSKEWINVEV-QAGDPLTLECPIEDTSGVHITWSRQFGK 2982

Query: 1736 DIKDGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKISTSGN 1912
            D +      +      L+I +A       Y C A NDAG     F V     PKI
Sbjct: 2983 DGQLDMRAQSSSDKSKLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNTPPKIFGDSF 3042

Query: 1913 RYINGSEGTETVIKCXXXXXXXXXXX-XKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQG 2089
                    T   I C              +G P+L    + + +    ++I + + + +G
Sbjct: 3043 STTEIVADTTLEIPCRTEGIPPPEISWFLDGKPILEMPGVTYKQGDLSLRIDNIKPNQEG 3102

Query: 2090 EYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYK 2269
             Y+C A NKAG A Q T + +   P+++       V +G Q T+ CE  G P+P + W K
Sbjct: 3103 RYTCVAENKAGRAEQDTYVEISEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLK 3162

Query: 2270 DNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVV 2449
            D E  T+  +    +TK   +     + +  G YTC A N    ++   D+ V++PP +
Sbjct: 3163 DGEPYTSDLLQ--FSTKLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEVLVPPRIE 3220

Query: 2450 PERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDD 2629
             E   +      T  + C  TG P P ++W R       N ++ +     L IRN    D
Sbjct: 3221 DEERVLQGKEGNTYMVHCQVTGRPVPYVTWKR-------NGKEIEQFNPVLHIRNATRAD 3273

Query: 2630 DGFYHCIAKSDAGQKIA-------------TRKLIVNKPSDRPAPIWVECDEKGKPKKTE 2770
            +G Y CIA ++AG  +A             T +   N      A I  EC   G PK T
Sbjct: 3274 EGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNIVEGESAKI--ECKIDGHPKPTI 3331

Query: 2771 YMIDRGDTP--DDNPQLLPWKDV--------EDSSLNGSIAYRCMPGPRSSRTVLLHAAP 2920
              + +G  P   DN  L P  D          D  L   +A            V ++  P
Sbjct: 3332 SWL-KGGRPFNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKP 3390

Query: 2921 QFIVKPKNTTAAI-GAIVELRCSAAGPPHPTITWAK-DGKLIEDSKFEIAYSH-LKVTLN 3091
                    T  A+ G  + L+C   G P PT+TW + D  +  DS+  I  ++ LK+
Sbjct: 3391 YIDETIDQTPKAVAGGEIILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNNYDLKINSV 3450

Query: 3092 STSDSGEYTCMAQNSVGSSTV---------SAFINVDNNILPTPKPSSNQKNVAVITCYE 3244
            +T D+G+Y+C+A N  G+ T            F+    N+    +  +   +  V +
Sbjct: 3451 TTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPL 3510

Query: 3245 RNQAYSRGLTWEYNGVPMPKNLAGIHFMN-NGSLVILDTSSLKEGDLELYTCKVRNRRRH 3421
             + ++ RG          P  L   + ++ +GS + ++ + L +G    Y C+  N
Sbjct: 3511 PSISWFRG--------DKPVYLYDRYSISPDGSHITINKAKLSDGG--KYICRASNEAG- 3559

Query: 3422 SIPHLTSAFEGVPEVKTIDKVEVNN---------GDSVVLDCEVTSDPLTTHVVWTKN-- 3568
                 TS  + + ++    K++ +N           ++ L+C ++  P    V+WTKN
Sbjct: 3560 -----TSDIDLILKILVPPKIDKSNIIGNPLAIVARTIYLECPISGIP-QPDVIWTKNGM 3613

Query: 3569 DQKMLDDDAIYXXXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNV 3718
            D  M D   I             +  D+G Y C A+N  GKA  D  L+V
Sbjct: 3614 DINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDV 3663



 Score =  362 bits (928), Expect = 6e-98
 Identities = 330/1318 (25%), Positives = 547/1318 (41%), Gaps = 79/1318 (5%)
 Frame = +2

Query: 2    ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH 181
            I G P P + W KNG D+   D  + +  N     I   +  D G Y+C   N  GK
Sbjct: 726  IRGKPHPKIRWFKNGKDLIKPDDYIKI--NEGQLHIMGAKDEDAGAYSCVGENMAGKDVQ 783

Query: 182  DFSLDVLSPPEF--DIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDG 355
              +L V   P      H  +  I+R+   +TL C   LA  I     ++ W K +  L
Sbjct: 784  VANLSVGRVPTIIESPHTVRVNIERQ---VTLQC---LAVGIPPP--EIEWQKGNVLLAT 835

Query: 356  DLTDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDV 535
                      DG  L I+ A +E+ G +TCIA N  G+ S    + +       +
Sbjct: 836  LNNPRYTQLADG-NLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVSPVLGHVPP 894

Query: 536  QPQVAVNQPTIMRCAVT-GHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAG 712
            + Q+   Q   + C V  G P PSI W+K+ K V +   I+I   G +L++   +    G
Sbjct: 895  EEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEG 954

Query: 713  KWSCVAENDAG----------VKELEMVLD-----VFTPPV-------VSVKSDNPIKAL 826
            K++C+A + AG          +K+ E V       VF P +       V+V +
Sbjct: 955  KYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLD 1014

Query: 827  GETITLFCNASGNPYPQLKWAKGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQA 1006
            GE   + C  SG P P + W   G  I  +     ++     L +    K+  G YTCQA
Sbjct: 1015 GEGFAIPCVVSGTPPPIITWYLDGRPITPNSRDFTVTADNT-LIVRKADKSYSGVYTCQA 1073

Query: 1007 LNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTA 1186
             N+AG +E   ++ ++  P I+      S  +      T+ C   G P P + W L+
Sbjct: 1074 TNSAGDNEQKTTIRIMNTPMISPG--QSSFNMVVDDLFTIPCDVYGDPKPVITWLLDDKP 1131

Query: 1187 LTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGT 1366
             T       V ++   + I NV+ + +G +TC+A+N AG+D     + V   P I+
Sbjct: 1132 FTEG-----VVNEDGSLTIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAENQ 1186

Query: 1367 KQV-IEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSG 1543
            +++ ++ +  V+EC  +  P P   W   G ++++ +       DG  L +   +  ++G
Sbjct: 1187 EKIALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDG-ALVLQNVKLENTG 1245

Query: 1544 IYLCSATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWT 1723
            +++C  +N AG    +YTL V   PKII+  PGV+    G    +PC   G P+ I +W
Sbjct: 1246 VFVCQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWN 1305

Query: 1724 LNGNDIKDGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKIS 1900
             NG D+K  E   ++   GTL I +A++  +  Y C   N+AG   +   V     P I
Sbjct: 1306 KNGIDLKMDEKKFSVDNLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHVDVQEPPIIL 1365

Query: 1901 TSGNRYINGSEGTETVIKCXXXXX-XXXXXXXKNGVPLLPSNNLIFSEDYKLIKILSTRL 2077
             S         G    +KC             + G+ +         E    + I S  +
Sbjct: 1366 PSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRGIAIGTDTKGYVVESDGTLVIQSASV 1425

Query: 2078 SDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERP--RTQVVHKGDQVTLWCEASGVPQP 2251
             D   Y+C A+N AG A     + V  +P I +      + + +    +L+C     P P
Sbjct: 1426 EDATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLP 1485

Query: 2252 AITWY-KDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIV 2428
             I+WY  D  L+ +    +T+  K+K  +F +   + +GVY C A N      +   + V
Sbjct: 1486 QISWYLNDKPLIDDKTSWKTSDDKRKLHVFKA-KITDSGVYKCVARNAAGEGSKSFQVEV 1544

Query: 2429 MIPPEVVPE--RMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQIL---- 2590
            ++P  +     +  V     + V L C  +G P P I+W+ D  + ++  +KY+
Sbjct: 1545 IVPLNLDESKYKKKVFAKEGEEVTLGCPVSGFPVPQINWVVDGTV-VEPGKKYKGATLSN 1603

Query: 2591 -GTTLAIRNVLPDDDGFYHCIAKSDA---------------------------GQKIATR 2686
             G TL   +V    +G YHC+A+S                             G+ I+
Sbjct: 1604 DGLTLHFDSVSVKQEGNYHCVAQSKGNILDIDVELSVLAVPIVGEDDNLEVFLGKDISLS 1663

Query: 2687 KLIVNKPSDRPAPIW-VECDEKGKPKKTEYMIDRGDTPDDNPQLLPWKDVEDSSLNGSIA 2863
              +  +  D+   +W +   E  +P       D    P D  +L     + D+    +
Sbjct: 1664 CDLQTESDDKTTFVWSINGSESDRP-------DNVQIPSDGHRLY----ITDAKPENNGK 1712

Query: 2864 YRCM---PGPRSSRTVLLHA-APQFIVKP---KNTTAAIGAIVELRCSAAGPPHPTITWA 3022
            Y C       ++ RT+ L    P   V+P    N        + L+C   G P PT+ W
Sbjct: 1713 YMCRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWK 1772

Query: 3023 KDGKLIEDS-KFEIAYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPK 3199
             DG  ++ S  F+ + S L++    T  S + +C A+N  G+++   FI   N   PT K
Sbjct: 1773 IDGNDVDKSWLFDESLSLLRIE-KLTGKSAQISCTAENKAGTASRDFFI--QNIAAPTFK 1829

Query: 3200 PSSNQKNV----AVITCYERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSL 3367
               +Q+ +      IT           +TW   G+P+ +N A I  ++N  L IL+ +
Sbjct: 1830 NEGDQETIFRESETITLDCPVSLGDFQITWMKQGLPLTENDA-IFTLDNTRLTILNANRD 1888

Query: 3368 KEGDLELYTCKVRNRRRHSIPHLTSAFEGVPEVK-TIDKVEVNNGDSVVLDCEVTSDPLT 3544
             E   ++YTC   N             + +P++K  +  +E+N G+ ++L C+   +P
Sbjct: 1889 HE---DIYTCVANNTAGQVSKDFDVVVQVLPKIKNAVVTLEINEGEEIILTCDAEGNPTP 1945

Query: 3545 THVVWTKNDQKMLDDDAIYXXXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNV 3718
            T   W  N Q  L  +A++             KY  GVYKC A+N +G+A     ++V
Sbjct: 1946 T-AKWDFN-QGDLPKEAVFVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAVKTINVHV 2001



 Score =  354 bits (909), Expect = 1e-95
 Identities = 319/1287 (24%), Positives = 525/1287 (40%), Gaps = 58/1287 (4%)
 Frame = +2

Query: 8    GIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDF 187
            G P P + W K+G  I   D R +         I   + +DQGRYTC ATN  G    +
Sbjct: 2504 GSPSPTITWLKDGNAIEPND-RYVFFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLEN 2562

Query: 188  SLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTD 367
            +L+V+ PP  D    +     EG +  L C      D     +DV W KD   ++ D
Sbjct: 2563 TLEVIIPPVIDGERREAVAVIEGFSSELFC------DSNSTGVDVEWQKDGLTINQDTLR 2616

Query: 368  N---VDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQ 538
                + I   G+K++   A   ++G YTCI  N AGEA   F   +  PP I    +
Sbjct: 2617 GDSFIQIPSSGKKMSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVNDPPSISDELSSAN 2676

Query: 539  PQVAVNQ-PTIMRCAVTGHPFPSIKWLKNGKEVTDDENI-RIVEQGQVLQILRTDSDHAG 712
             Q  V   P  + C V+G P P + WL + K +  D     +   G+ L+I+R+  +HAG
Sbjct: 2677 IQTIVPYYPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIVRSQVEHAG 2736

Query: 713  KWSCVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGN-PYPQLKWA 889
             ++C A+N+ G    + ++ V  PP    + +  +  +G+T+ L CNA  + P   + W
Sbjct: 2737 TYTCEAQNNVGKARKDFLVRVTAPPHFEKEREEVVARVGDTMLLTCNAESSVPLSSVYWH 2796

Query: 890  KGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEI 1069
                 + +    ++ +     L++ +++  D G Y C A+N AG ++    + V+  P
Sbjct: 2797 AHDESVQNGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIETPYF 2856

Query: 1070 NRDGIDMSPRLPA--QQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQI 1243
                +D     P    + LTL C A G P P + +  +G  L  S     + S    + I
Sbjct: 2857 ----LDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDIIGST---LVI 2909

Query: 1244 NNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTK-QVIEGELAVIECLVEGY 1420
            +N     +G YTC AEN AG       V+V+  P +S      +V  G+   +EC +E
Sbjct: 2910 DNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLECPIEDT 2969

Query: 1421 PAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTL 1600
                ++W R   +        +  +D   L I++A   D+  Y C A N+AG A+  + +
Sbjct: 2970 SGVHITWSRQFGKDGQLDMRAQSSSDKSKLYIMQATPEDADSYSCIAVNDAGGAEAVFQV 3029

Query: 1601 EVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADG 1780
             V   PKI   +       + +   +PC   G P P ISW L+G  I +         D
Sbjct: 3030 TVNTPPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFLDGKPILEMPGVTYKQGDL 3089

Query: 1781 TLHIEKAE-ERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKC 1957
            +L I+  +  +   Y C A+N AG    +  V+    P++    +  +   EG +T I+C
Sbjct: 3090 SLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEISEPPRV-VMASEVMRVVEGRQTTIRC 3148

Query: 1958 XXXXXXXXXXX-XKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQ 2134
                         K+G P   S+ L FS     + +  T L+D G Y+C A NKAG +
Sbjct: 3149 EVFGNPEPVVNWLKDGEPYT-SDLLQFSTKLSYLHLRETTLADGGTYTCIATNKAGESQT 3207

Query: 2135 KTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETAT 2314
             T++ V V P+I +  R     +G+   + C+ +G P P +TW ++ + +
Sbjct: 3208 TTDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEIEQFN------ 3261

Query: 2315 TKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVF 2494
                 +   + + +  G Y+C A N   +   D  + V   P         +    ++
Sbjct: 3262 ---PVLHIRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNIVEGESAK 3318

Query: 2495 LSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQK 2674
            + C   G P+P ISW++       +N      G TL I      D G Y C+A +  G
Sbjct: 3319 IECKIDGHPKPTISWLKGGRPFNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDS 3378

Query: 2675 -------IATRKLIVNKPSDRP-----APIWVECDEKGKPKKTEYMIDRGD--TPDDNPQ 2812
                   + T+  I       P       I ++C   G P  T     RGD   P+D+
Sbjct: 3379 EQDFKVNVYTKPYIDETIDQTPKAVAGGEIILKCPVLGNPTPTVTW-KRGDDAVPNDSRH 3437

Query: 2813 LLPWK-DVEDSSLNGSIA--YRCMPGPRSSRTVLLHAA-----PQFIVKPKNTTAAI-GA 2965
             +    D++ +S+    A  Y C+    +      +AA     P F+ K  N    I
Sbjct: 3438 TIVNNYDLKINSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIEND 3497

Query: 2966 IVELRCSAAGPPHPTITWAKDGK---LIEDSKFEIAYSHLKVTLNSTSDSGEYTCMAQNS 3136
             + + C     P P+I+W +  K   L +        SH+ +     SD G+Y C A N
Sbjct: 3498 TITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAKLSDGGKYICRASNE 3557

Query: 3137 VGSSTVSAFINVDNNILPTPKPSSN--QKNVAVITCYERNQAYSRGLTWEYNGVPMPKNL 3310
             G+S +   + +   ++P     SN     +A++       A +  L    +G+P P  +
Sbjct: 3558 AGTSDIDLILKI---LVPPKIDKSNIIGNPLAIV-------ARTIYLECPISGIPQPDVI 3607

Query: 3311 ---AGIHFMNNGSLVILDTSSLKEG-------DLELYTCKVRNRRRHSIPHLTSAFEGVP 3460
                G+      S VIL  ++   G       D   YTC   NR   +    +      P
Sbjct: 3608 WTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPP 3667

Query: 3461 E--VKTIDKVEVNNGDSVVLDCEV-TSDPLTTHVV---WTKNDQKM---LDDDAIYXXXX 3613
            E  +          GD++ L C +  ++ +   V+   WTK+ + +   L D+
Sbjct: 3668 EFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDG 3727

Query: 3614 XXXXXXXXEKYDEGVYKCVASNSIGKA 3694
                       + G+Y C+A N  G+A
Sbjct: 3728 RKLTISQASLENAGLYTCIALNRAGEA 3754



 Score =  339 bits (870), Expect = 3e-91
 Identities = 345/1334 (25%), Positives = 552/1334 (40%), Gaps = 83/1334 (6%)
 Frame = +2

Query: 14   PQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSL 193
            P P + W  N   +    +    + +     +   ++TD G Y C A N  G+ S  F +
Sbjct: 1483 PLPQISWYLNDKPLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQV 1542

Query: 194  DVLSPPEFDIHGTQPTI-KREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALD-GDLTD 367
            +V+ P   D    +  +  +EG+ +TL CP+         V  ++W  D   ++ G
Sbjct: 1543 EVIVPLNLDESKYKKKVFAKEGEEVTLGCPVS-----GFPVPQINWVVDGTVVEPGKKYK 1597

Query: 368  NVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQV 547
               +S+DG  L     S++  G Y C+A ++     ++ ++ +L+ P++     D   +V
Sbjct: 1598 GATLSNDGLTLHFDSVSVKQEGNYHCVAQSKGNILDIDVELSVLAVPIVG---EDDNLEV 1654

Query: 548  AVNQPTIMRCAVT--GHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWS 721
             + +   + C +        +  W  NG E    +N++I   G  L I     ++ GK+
Sbjct: 1655 FLGKDISLSCDLQTESDDKTTFVWSINGSESDRPDNVQIPSDGHRLYITDAKPENNGKYM 1714

Query: 722  CVAENDAGVKELEMVLDVFTPPV-VSVKSDNPIKALGET-ITLFCNASGNPYPQLKWAKG 895
            C   N AG  E  + LDV  PPV V    +   K +G   I L C  +GNP P + W
Sbjct: 1715 CRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKID 1774

Query: 896  G-----SLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVP 1060
            G     S +FD       SL   R++    K   +   +C A N AGT+     +  +
Sbjct: 1775 GNDVDKSWLFDE------SLSLLRIEKLTGKSAQI---SCTAENKAGTASRDFFIQNIAA 1825

Query: 1061 PEINRDGIDMSPRLPAQQSLTLQCLAQGKPVP----QMRWTLNGTALTHSTPGITVASDS 1228
            P    +G D        +++TL C     PV     Q+ W   G  LT +    T+  D+
Sbjct: 1826 PTFKNEG-DQETIFRESETITLDC-----PVSLGDFQITWMKQGLPLTENDAIFTL--DN 1877

Query: 1229 TFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGG-TKQVIEGELAVIEC 1405
            T + I N +   + +YTC A N AG  +  ++V V   P I N   T ++ EGE  ++ C
Sbjct: 1878 TRLTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQVLPKIKNAVVTLEINEGEEIILTC 1937

Query: 1406 LVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQ 1585
              EG P P   W  + N+ +   + V +V +   + +       +G+Y C ATN+ G A
Sbjct: 1938 DAEGNPTPTAKW--DFNQGDLPKEAV-FVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAV 1994

Query: 1586 QAYTLEVLVSPKIITS-TPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENG- 1759
            +   + V   P+  +  T   LT +     +L C V       ISWT+NG       +G
Sbjct: 1995 KTINVHVRTKPRFESGLTESELTVNLTRSITLECDVDDAIGVGISWTVNGKPFLAETDGV 2054

Query: 1760 HTIGADGTLHIEKAE-ERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEG 1936
             T+     LHI  A+ + H  Y CT  N+AG  T  F +   V P I   G  Y    E
Sbjct: 2055 QTLAGGRFLHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQVPPTIVNEGGEY-TVIEN 2113

Query: 1937 TETVIKCXXXXXXXXXXX-XKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAAN 2113
               V+ C             K+G P+    ++    + +  KI+   ++ +G Y C A N
Sbjct: 2114 NSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEGQQFKIVHAEIAHKGSYICMAKN 2173

Query: 2114 KAGNATQKTNLNVGVAPKIMERPRTQVVH-KGDQVTLWCEASGVP--QPAITWYKDNELL 2284
              G A    ++++   P I +  +  V   KG  +   C        +  I W ++ + +
Sbjct: 2174 DVGTAEISFDVDIITRPMIQKGIKNIVTAIKGGALPFKCPIDDDKNFKGQIIWLRNYQPI 2233

Query: 2285 TNTGVDETAT--TKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVV--P 2452
                 D   T  +  + +   +++ +  G Y+C+ +N       D    V++PP ++
Sbjct: 2234 DLEAEDARITRLSNDRRLTILNVTENDEGQYSCRVKNDAGENSFDFKATVLVPPTIIMLD 2293

Query: 2453 ERMNVSTNPRQTVFLSCNATGIPEPVISWMRDS------NIA--IQNNEKYQILGTTLAI 2608
            +  N +     TV LSC ATG PEP I+W +D       NIA  I N E   + G  L I
Sbjct: 2294 KDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGE---LNGNQLKI 2350

Query: 2609 RNVLPDDDGFYHCIAKSDAG---QKIATRKLIVNK------PSDRPA----------PIW 2731
              +   D G Y C A + AG   Q +    + + K      PSD  +          P++
Sbjct: 2351 TRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQNERVVISCPVY 2410

Query: 2732 VECDEK------GKPKKTEYMIDRGDTPDDNPQLLPWKDVE-DSSLNGSIAYRCMPGPRS 2890
                 K      GKP +++  +    T  +  +L  +K  E DSS    IA       +
Sbjct: 2411 ARPPAKITWLKAGKPLQSDKFVK---TSANGQKLYLFKLRETDSSKYTCIATNEAGTDKR 2467

Query: 2891 SRTVLLHAAPQF----IVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSK-- 3052
               V +  AP F    IV+    T   G    L C A G P PTITW KDG  IE +
Sbjct: 2468 DFKVSMLVAPSFDEPNIVR--RITVNSGNPSTLHCPAKGSPSPTITWLKDGNAIEPNDRY 2525

Query: 3053 -FEIAYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAV 3229
             F  A   L+++    SD G YTC+A NSVGS  +   + V   I+P       ++ VAV
Sbjct: 2526 VFFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLENTLEV---IIPPVIDGERREAVAV 2582

Query: 3230 ITCYERN---QAYSRGLT--WEYNGVPMPKN-LAGIHFMN-NGSLVILDTSSLKEGDLEL 3388
            I  +       + S G+   W+ +G+ + ++ L G  F+    S   +   S ++ D
Sbjct: 2583 IEGFSSELFCDSNSTGVDVEWQKDGLTINQDTLRGDSFIQIPSSGKKMSFLSARKSDSGR 2642

Query: 3389 YTCKVRNRRRHSIPHLTSAFEGVPEVKTIDKVEVNNGDSVV------LDCEVTSDPLTTH 3550
            YTC VRN    +      A    P +   D++   N  ++V      ++C V+  P
Sbjct: 2643 YTCIVRNPAGEARKLFDFAVNDPPSIS--DELSSANIQTIVPYYPVEINCVVSGSP-HPK 2699

Query: 3551 VVWTKNDQKMLDDDAIYXXXXXXXXXXXXEKYDE--GVYKCVASNSIGKAFDDTQLNVYG 3724
            V W  +D+ +  D A Y                E  G Y C A N++GKA  D  + V
Sbjct: 2700 VYWLFDDKPLEPDSAAYELTNNGETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLVRV-- 2757

Query: 3725 GSSRREAYKKENED 3766
              +    ++KE E+
Sbjct: 2758 --TAPPHFEKEREE 2769



 Score =  309 bits (792), Expect = 4e-82
 Identities = 333/1324 (25%), Positives = 536/1324 (40%), Gaps = 97/1324 (7%)
 Frame = +2

Query: 23   DVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVL 202
            ++ WT+ G  +            N T  I +V   D G Y C A N GG ++    LD++
Sbjct: 550  EIRWTRYGATV-FNGPNTERNPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMRLDIM 608

Query: 203  SPPEFDIHGTQPTIK-REGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDI 379
             PP   +         REG  + L+C     E + D   +V W    R L  D      +
Sbjct: 609  EPPSVKVTPQDVYFNMREG--VNLSC-----EAMGDPKPEVHWYFKGRHLLNDY--KYQV 659

Query: 380  SDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQ 559
              D + L I  A+  + G Y C A+++AG+A     + + +PP ++I +N +   V
Sbjct: 660  GQDSKFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKM--MVGRGD 717

Query: 560  PTIMRC-AVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSCVAEN 736
                 C  + G P P I+W KNGK++   ++   + +GQ L I+    + AG +SCV EN
Sbjct: 718  RVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQ-LHIMGAKDEDAGAYSCVGEN 776

Query: 737  DAGVKELEMVLDVFTPPVVSVKSDNPIKA-LGETITLFCNASGNPYPQLKWAKGGSLIFD 913
             AG       L V   P + ++S + ++  +   +TL C A G P P+++W KG  L+
Sbjct: 777  MAGKDVQVANLSVGRVPTI-IESPHTVRVNIERQVTLQCLAVGIPPPEIEWQKGNVLLAT 835

Query: 914  SPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDV--LVPPEINRDGID 1087
              +     L    L I   +  D G +TC A N  G    S ++ V  LV P +    +
Sbjct: 836  LNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVSPVLGH--VP 893

Query: 1088 MSPRLPAQQSLTLQC-LAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLSD 1264
               +L   Q LTL C +  G P P + W  +   +    P I +    + +++   +  D
Sbjct: 894  PEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEG-PTIKIEGGGSLLRLRGGNPKD 952

Query: 1265 KGVYTCYAENVAGSDNLMYNVDVVQAP-----------------------VISNGGTKQV 1375
            +G YTC A + AG+  L  NV +++ P                       V     T  V
Sbjct: 953  EGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDV 1012

Query: 1376 IEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLC 1555
            ++GE   I C+V G P P ++W  +G  +    +    VT    L + +A    SG+Y C
Sbjct: 1013 LDGEGFAIPCVVSGTPPPIITWYLDGRPITPNSRDFT-VTADNTLIVRKADKSYSGVYTC 1071

Query: 1556 SATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSS--GSKFSLPCAVRGYPDPIISWTLN 1729
             ATN AG  +Q  T+ ++ +P I   +PG  + +      F++PC V G P P+I+W L+
Sbjct: 1072 QATNSAGDNEQKTTIRIMNTPMI---SPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLD 1128

Query: 1730 GNDIKDGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKISTS 1906
                 +G     +  DG+L I    E H   + C A+N AG DT    +     P I+
Sbjct: 1129 DKPFTEG----VVNEDGSLTIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAE 1184

Query: 1907 GNRYINGSEGTETVIKCXXXX-----XXXXXXXXKNGVPLLPSNNLIFSEDYKLIKILST 2071
                I   +  + V++C                 K    L+P       ED  L+ + +
Sbjct: 1185 NQEKI-ALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHT---IREDGALV-LQNV 1239

Query: 2072 RLSDQGEYSCTAANKAGNATQKTNLNVGVAPKIM-ERPRTQVVHKGDQVTLWCEASGVPQ 2248
            +L + G + C  +N AG  +    L V   PKI+ E P    V KG  + + C A+GVP+
Sbjct: 1240 KLENTGVFVCQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPE 1299

Query: 2249 PAITWYKDNELLTNTGVDETATTKKKSV-------IFSSISPSQAGVYTCKAENWVASTE 2407
               TW K+       G+D     KK SV       I+ +   +  G Y C   N   +++
Sbjct: 1300 VIRTWNKN-------GIDLKMDEKKFSVDNLGTLRIYEA-DKNDIGNYNCVVTNEAGTSQ 1351

Query: 2408 EDIDLIVMIPPEVVPE-RMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQ 2584
                + V  PP ++P  + N +      V L C     P   ++W R   IAI  + K
Sbjct: 1352 MTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFR-RGIAIGTDTKGY 1410

Query: 2585 ILGT--TLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVNKPSD--RPAPIWVECDEKG 2752
            ++ +  TL I++   +D   Y C A + AG+  A  ++ V    D   P  +  E  ++
Sbjct: 1411 VVESDGTLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESIKES 1470

Query: 2753 KPKKTEYMIDRGDTP------DDNPQL---LPWKDVED--------SSLNGSIAYRCM-- 2875
             P      +     P      +D P +     WK  +D        + +  S  Y+C+
Sbjct: 1471 HPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVAR 1530

Query: 2876 ----PGPRSSRT-VLLHAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLI 3040
                 G +S +  V++          K   A  G  V L C  +G P P I W  DG ++
Sbjct: 1531 NAAGEGSKSFQVEVIVPLNLDESKYKKKVFAKEGEEVTLGCPVSGFPVPQINWVVDGTVV 1590

Query: 3041 EDSK--FEIAYSHLKVTLN----STSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKP 3202
            E  K       S+  +TL+    S    G Y C+AQ    S      I+V+ ++L  P
Sbjct: 1591 EPGKKYKGATLSNDGLTLHFDSVSVKQEGNYHCVAQ----SKGNILDIDVELSVLAVPIV 1646

Query: 3203 SSNQ-------KNVAVITCYERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNG-SLVILDT 3358
              +        K++++    +          W  NG    +    +   ++G  L I D
Sbjct: 1647 GEDDNLEVFLGKDISLSCDLQTESDDKTTFVWSINGSESDRP-DNVQIPSDGHRLYITDA 1705

Query: 3359 SSLKEGDLELYTCKVRN-----RRRHSIPHLTSAFEGVPEVKTIDKVEVNNGDSVVLDCE 3523
                 G    Y C+V N      R  ++  L       P  +   K+  NN   ++L C+
Sbjct: 1706 KPENNGK---YMCRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLIGNN--PIILQCQ 1760

Query: 3524 VTSDPLTTHVVWTKN----DQKMLDDDAIYXXXXXXXXXXXXEKYDEGVYKCVASNSIGK 3691
            VT +P  T V+W  +    D+  L D+++             +        C A N  G
Sbjct: 1761 VTGNPKPT-VIWKIDGNDVDKSWLFDESLSLLRIEKLTGKSAQ------ISCTAENKAGT 1813

Query: 3692 AFDD 3703
            A  D
Sbjct: 1814 ASRD 1817



 Score =  299 bits (766), Expect = 4e-79
 Identities = 288/1154 (24%), Positives = 473/1154 (40%), Gaps = 77/1154 (6%)
 Frame = +2

Query: 542  QVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWS 721
            Q  V +   + C V      +I W+K G+++             V  I       AG++
Sbjct: 439  QEFVGRDLNLSCTVESASAYTIYWVKTGEDIIGGPLFYHNTDTSVWTIPELSLKDAGEYE 498

Query: 722  CVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGS 901
            C   ++ G   ++  ++    P       N    LGE   L C+       +++W + G+
Sbjct: 499  CRVISNNGNYSVKTRVETRESPPEIFGVRNVSVPLGEAAFLHCSTRSAGEVEIRWTRYGA 558

Query: 902  LIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDG 1081
             +F+ P+  R    G  L I H+ + D G Y C A NA G S   + +D++ PP +
Sbjct: 559  TVFNGPNTERNPTNGT-LKIHHVTRADAGVYECMARNAGGMSTRKMRLDIMEPPSVKVTP 617

Query: 1082 IDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLS 1261
             D+   +  ++ + L C A G P P++ W   G  L +      V  DS F+ I + +
Sbjct: 618  QDVYFNM--REGVNLSCEAMGDPKPEVHWYFKGRHLLNDYK-YQVGQDSKFLYIRDATHH 674

Query: 1262 DKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVI-EGELAVIEC-LVEGYPAPQV 1435
            D+G Y C A + AG      ++ +   P +     K ++  G+    EC  + G P P++
Sbjct: 675  DEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKI 734

Query: 1436 SWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVS 1615
             W +NG  +      ++ + +G+ L I+ A+  D+G Y C   N AG   Q   L V
Sbjct: 735  RWFKNGKDLIKPDDYIK-INEGQ-LHIMGAKDEDAGAYSCVGENMAGKDVQVANLSVGRV 792

Query: 1616 PKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENG--HTIGADGTLH 1789
            P II S P  +  +   + +L C   G P P I W   GN +    N   +T  ADG L
Sbjct: 793  PTIIES-PHTVRVNIERQVTLQCLAVGIPPPEIEWQ-KGNVLLATLNNPRYTQLADGNLL 850

Query: 1790 IEKAE-ERHLIYECTAKNDAG--ADTLEFPVQTIVAPKIS--TSGNRYINGSEGTETVIK 1954
            I  A+ E    + C A+N  G  + +    V  +V+P +       + I G + T + +
Sbjct: 851  ITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVSPVLGHVPPEEQLIEGQDLTLSCV- 909

Query: 1955 CXXXXXXXXXXXXKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQ 2134
                         K+  P+     +       L+++      D+G+Y+C A + AGN+T
Sbjct: 910  VVLGTPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEGKYTCIAVSPAGNSTL 969

Query: 2135 KTNLNVGVAPKIMERPRTQVVHK----------------------GDQVTLWCEASGVPQ 2248
              N+ +   P+ + +P   +V K                      G+   + C  SG P
Sbjct: 970  HINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEGFAIPCVVSGTPP 1029

Query: 2249 PAITWYKDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIV 2428
            P ITWY D   +T    D T T    ++I      S +GVYTC+A N     E+   + +
Sbjct: 1030 PIITWYLDGRPITPNSRDFTVTADN-TLIVRKADKSYSGVYTCQATNSAGDNEQKTTIRI 1088

Query: 2429 MIPPEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQN--NEKYQILGTTL 2602
            M  P + P + + +        + C+  G P+PVI+W+ D     +   NE       +L
Sbjct: 1089 MNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLDDKPFTEGVVNE-----DGSL 1143

Query: 2603 AIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVN-----------KPSDRPAPIWVECDEK 2749
             I NV     G + C A++ AG    T  L V+           K + +   I +EC  K
Sbjct: 1144 TIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAENQEKIALQNDDIVLECPAK 1203

Query: 2750 GKPKKTEYMIDRGDTPDDNPQLLPWKDVEDSS-------LNGSIAYRC----MPGPRS-S 2893
              P         G+  D   QL+P    ED +       L  +  + C    + G  S S
Sbjct: 1204 ALPPPVRLWTYEGEKIDS--QLIPHTIREDGALVLQNVKLENTGVFVCQVSNLAGEDSLS 1261

Query: 2894 RTVLLHAAPQFIVK-PKNTTAAIGAIVELRCSAAGPPHPTITWAKDG--KLIEDSKFEI- 3061
             T+ +H  P+ I + P       G  +E+ C A G P    TW K+G    +++ KF +
Sbjct: 1262 YTLTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVD 1321

Query: 3062 AYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVI--- 3232
                L++     +D G Y C+  N  G+S ++  ++V     P   PS+   N AV+
Sbjct: 1322 NLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHVDVQEP--PIILPSTQTNNTAVVGDR 1379

Query: 3233 ---TCYERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKV 3403
                CY    +    +TW   G+ +  +  G    ++G+LVI    S    D  +YTCK
Sbjct: 1380 VELKCYV-EASPPASVTWFRRGIAIGTDTKGYVVESDGTLVI---QSASVEDATIYTCKA 1435

Query: 3404 RNRRRHSIPHLTSAFEGVPEVKTIDKV---EVNNGDSVVLDCEVTSDPLTTHVVWTKNDQ 3574
             N    +  +L       P++K  D V    +       L C V S+PL   + W  ND+
Sbjct: 1436 SNPAGKAEANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPL-PQISWYLNDK 1494

Query: 3575 KMLDDDAIYXXXXXXXXXXXXEK--YDEGVYKCVASNSIGKAFDDTQ------LNVYGGS 3730
             ++DD   +            +    D GVYKCVA N+ G+     Q      LN+
Sbjct: 1495 PLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLNLDESK 1554

Query: 3731 SRREAYKKENEDAS 3772
             +++ + KE E+ +
Sbjct: 1555 YKKKVFAKEGEEVT 1568



 Score =  265 bits (678), Expect = 6e-69
 Identities = 294/1175 (25%), Positives = 469/1175 (39%), Gaps = 79/1175 (6%)
 Frame = +2

Query: 254  GDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGD--LTDNVDISDDGRKLTISQASLEN 427
            G  + L+C ++ A         + W K    + G      N D S      TI + SL++
Sbjct: 443  GRDLNLSCTVESAS-----AYTIYWVKTGEDIIGGPLFYHNTDTS----VWTIPELSLKD 493

Query: 428  AGLYTCIALNRAGEASLEFKVEIL-SPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPS 604
            AG Y C  ++  G  S++ +VE   SPP I   RN     V + +   + C+
Sbjct: 494  AGEYECRVISNNGNYSVKTRVETRESPPEIFGVRN---VSVPLGEAAFLHCSTRSAGEVE 550

Query: 605  IKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTP 784
            I+W + G  V +  N         L+I       AG + C+A N  G+   +M LD+  P
Sbjct: 551  IRWTRYGATVFNGPNTERNPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMRLDIMEP 610

Query: 785  PVVSVKSDNPIKALGETITLFCNASGNPYPQLKW-AKGGSLIFDSPDGARISLKGARLDI 961
            P V V   +    + E + L C A G+P P++ W  KG  L+ D     ++      L I
Sbjct: 611  PSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLLNDYK--YQVGQDSKFLYI 668

Query: 962  PHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQC-LA 1138
                  D G Y C+A++ AG +  +  + +  PP++  + I     +     ++ +C
Sbjct: 669  RDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKV--EIIQNKMMVGRGDRVSFECKTI 726

Query: 1139 QGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLM 1318
            +GKP P++RW  NG  L    P   +  +   + I      D G Y+C  EN+AG D  +
Sbjct: 727  RGKPHPKIRWFKNGKDLI--KPDDYIKINEGQLHIMGAKDEDAGAYSCVGENMAGKDVQV 784

Query: 1319 YNVDVVQAP-VISNGGTKQVIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRY-- 1489
             N+ V + P +I +  T +V       ++CL  G P P++ W + GN +   +   RY
Sbjct: 785  ANLSVGRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEW-QKGNVLLATLNNPRYTQ 843

Query: 1490 VTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEV--LVSPKIITSTPGVLTPSSG 1663
            + DG +L I +A+  D G + C A N  G   Q+ TL V  LVSP ++   P       G
Sbjct: 844  LADGNLL-ITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVSP-VLGHVPPEEQLIEG 901

Query: 1664 SKFSLPC-AVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKAEER-HLIYECTAK 1837
               +L C  V G P P I W  +   +++G      G    L +     +    Y C A
Sbjct: 902  QDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEGKYTCIAV 961

Query: 1838 NDAGADTLEFPVQTIVAPK--------------ISTSGNRYINGSEGTETV-------IK 1954
            + AG  TL   VQ I  P+              IS    +++     T  V       I
Sbjct: 962  SPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEGFAIP 1021

Query: 1955 CXXXXX-XXXXXXXKNGVPLLP-SNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNA 2128
            C              +G P+ P S +   + D  LI +     S  G Y+C A N AG+
Sbjct: 1022 CVVSGTPPPIITWYLDGRPITPNSRDFTVTADNTLI-VRKADKSYSGVYTCQATNSAGDN 1080

Query: 2129 TQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDET 2308
             QKT + +   P I     +  +   D  T+ C+  G P+P ITW  D++  T   V+E
Sbjct: 1081 EQKTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLDDKPFTEGVVNED 1140

Query: 2309 ATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQT 2488
                  S+   +++ +  G +TC A+N   +    + L V   P +  E
Sbjct: 1141 G-----SLTIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAENQEKIALQNDD 1195

Query: 2489 VFLSCNATGIPEPVISWMRDSNIAIQNNEKYQIL-GTTLAIRNVLPDDDGFYHCIAKSDA 2665
            + L C A  +P PV  W  +          + I     L ++NV  ++ G + C   + A
Sbjct: 1196 IVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDGALVLQNVKLENTGVFVCQVSNLA 1255

Query: 2666 GQKIATRKLIVN-KP---SDRPA--------PIWVECDEKGKPKKTEYMIDRG-----DT 2794
            G+   +  L V+ KP   S+ P          I + C   G P+        G     D
Sbjct: 1256 GEDSLSYTLTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDE 1315

Query: 2795 PDDNPQLLPWKDVEDSSLNGSIAYRCM---PGPRSSRTVLLHAAPQFIVKPK---NTTAA 2956
               +   L    + ++  N    Y C+       S  T  +      I+ P    N TA
Sbjct: 1316 KKFSVDNLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAV 1375

Query: 2957 IGAIVELRCSAAGPPHPTITWAKDGKLI-EDSKFEIAYSHLKVTLNSTS--DSGEYTCMA 3127
            +G  VEL+C     P  ++TW + G  I  D+K  +  S   + + S S  D+  YTC A
Sbjct: 1376 VGDRVELKCYVEASPPASVTWFRRGIAIGTDTKGYVVESDGTLVIQSASVEDATIYTCKA 1435

Query: 3128 QNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITCYERNQAYSRGLTWEYNGVPMPKN 3307
             N  G +        + N+  T   S + K+  V+T     +++   L       P+P+
Sbjct: 1436 SNPAGKA--------EANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQ- 1486

Query: 3308 LAGIHFMNNGSLVILDTSSLKEGD----LELYTCKVRNRRRHSIPHLTSAFEG------- 3454
               I +  N   +I D +S K  D    L ++  K+ +   +      +A EG
Sbjct: 1487 ---ISWYLNDKPLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVE 1543

Query: 3455 ------VPEVKTIDKVEVNNGDSVVLDCEVTSDPL 3541
                  + E K   KV    G+ V L C V+  P+
Sbjct: 1544 VIVPLNLDESKYKKKVFAKEGEEVTLGCPVSGFPV 1578


>gi|17568541|ref|NP_509635.1| high Incidence of Males due to increased
            X chromosome loss HIM-4, hemicentin, cell adhesion and
            meiotic chromosome segregation factor (570.8 kD) (him-4)
            [Caenorhabditis elegans]
 gi|11359751|pir||T43290 hemicentin precursor - Caenorhabditis elegans
 gi|3328186|gb|AAC26792.1| hemicentin precursor [Caenorhabditis
            elegans]
 gi|3875956|emb|CAA87336.1| C. elegans HIM-4 protein (corresponding
            sequence F15G9.4b) [Caenorhabditis elegans]
 gi|3879658|emb|CAA87345.1| C. elegans HIM-4 protein (corresponding
            sequence F15G9.4b) [Caenorhabditis elegans]
          Length = 5198

 Score = 3091 bits (8013), Expect = 0.0
 Identities = 1524/1601 (95%), Positives = 1524/1601 (95%), Gaps = 23/1601 (1%)
 Frame = +2

Query: 2    ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH 181
            ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH
Sbjct: 3598 ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH 3657

Query: 182  DFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDL 361
            DFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDL
Sbjct: 3658 DFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDL 3717

Query: 362  TDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQP 541
            TDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQP
Sbjct: 3718 TDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQP 3777

Query: 542  QVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWS 721
            QVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWS
Sbjct: 3778 QVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWS 3837

Query: 722  CVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGS 901
            CVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGS
Sbjct: 3838 CVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGS 3897

Query: 902  LIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDG 1081
            LIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDG
Sbjct: 3898 LIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDG 3957

Query: 1082 IDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLS 1261
            IDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLS
Sbjct: 3958 IDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLS 4017

Query: 1262 DKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVIEGELAVIECLVEGYPAPQVSW 1441
            DKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVIEGELAVIECLVEGYPAPQVSW
Sbjct: 4018 DKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVIEGELAVIECLVEGYPAPQVSW 4077

Query: 1442 LRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPK 1621
            LRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPK
Sbjct: 4078 LRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPK 4137

Query: 1622 IITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKA 1801
            IITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKA
Sbjct: 4138 IITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKA 4197

Query: 1802 EERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCXXXXXXXX 1981
            EERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKC
Sbjct: 4198 EERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCEIESESSE 4257

Query: 1982 XXXXKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVA 2161
                KNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVA
Sbjct: 4258 FSWSKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVA 4317

Query: 2162 PKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATTKKKSVIFS 2341
            PKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATTKKKSVIFS
Sbjct: 4318 PKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATTKKKSVIFS 4377

Query: 2342 SISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFLSCNATGIP 2521
            SISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFLSCNATGIP
Sbjct: 4378 SISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFLSCNATGIP 4437

Query: 2522 EPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVN 2701
            EPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVN
Sbjct: 4438 EPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVN 4497

Query: 2702 KPSDRPAPIWVECDEKGKPKKTEYMIDRGDTPDDNPQLLPWKDVEDSSLNGSIAYRCMPG 2881
            KPSDRPAPIWVECDEKGKPKKTEYMIDRGDTPDDNPQLLPWKDVEDSSLNGSIAYRCMPG
Sbjct: 4498 KPSDRPAPIWVECDEKGKPKKTEYMIDRGDTPDDNPQLLPWKDVEDSSLNGSIAYRCMPG 4557

Query: 2882 PRSSRTVLLHAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEI 3061
            PRSSRTVLLHAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEI
Sbjct: 4558 PRSSRTVLLHAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEI 4617

Query: 3062 AYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITCY 3241
            AYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITCY
Sbjct: 4618 AYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITCY 4677

Query: 3242 ERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRH 3421
            ERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRH
Sbjct: 4678 ERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRH 4737

Query: 3422 SIPHLTSAFEGVPEVKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIY 3601
            SIPHLTSAFEGVPEVKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIY
Sbjct: 4738 SIPHLTSAFEGVPEVKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIY 4797

Query: 3602 XXXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNVY-------------------- 3721
                        EKYDEGVYKCVASNSIGKAFDDTQLNVY
Sbjct: 4798 VLPNNSLVLLNVEKYDEGVYKCVASNSIGKAFDDTQLNVYEGDFLPLTGFEGSGINIDDS 4857

Query: 3722 ---GGSSRREAYKKENEDASXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAKQYPTDDYH 3892
               GGSSRREAYKKENEDAS                              AKQYPTDDYH
Sbjct: 4858 SNAGGSSRREAYKKENEDASTTTITTTSPTTTTTETPLTTTIIPALITLPAKQYPTDDYH 4917

Query: 3893 EGSANDDGFGPTTQDSLFEFNPPLHPEISVVNTDCAGTINENGDCVDKDGKTHNLKILTG 4072
            EGSANDDGFGPTTQDSLFEFNPPLHPEISVVNTDCAGTINENGDCVDKDGKTHNLKILTG
Sbjct: 4918 EGSANDDGFGPTTQDSLFEFNPPLHPEISVVNTDCAGTINENGDCVDKDGKTHNLKILTG 4977

Query: 4073 ENHCPEGFAMNPHTRICEDLDECAFYQPCDFECINYDGGFQCNCPLGYELAEEGCRDVNE 4252
            ENHCPEGFAMNPHTRICEDLDECAFYQPCDFECINYDGGFQCNCPLGYELAEEGCRDVNE
Sbjct: 4978 ENHCPEGFAMNPHTRICEDLDECAFYQPCDFECINYDGGFQCNCPLGYELAEEGCRDVNE 5037

Query: 4253 CESVRCEDGKACFNQLGGYECIDDPCPANYSLVDDRYCEPECENCTSTPIQVHMLAIPSG 4432
            CESVRCEDGKACFNQLGGYECIDDPCPANYSLVDDRYCEPECENCTSTPIQVHMLAIPSG
Sbjct: 5038 CESVRCEDGKACFNQLGGYECIDDPCPANYSLVDDRYCEPECENCTSTPIQVHMLAIPSG 5097

Query: 4433 LPISHIATLTAYDKSGRVLNDTTYAISDTGAPLARGRMTSGPFTIKAVKRGHAQVWTNRV 4612
            LPISHIATLTAYDKSGRVLNDTTYAISDTGAPLARGRMTSGPFTIKAVKRGHAQVWTNRV
Sbjct: 5098 LPISHIATLTAYDKSGRVLNDTTYAISDTGAPLARGRMTSGPFTIKAVKRGHAQVWTNRV 5157

Query: 4613 LAAGDHHKVRVRAHSDHATNELHAPKETNFLVLINVGQYPF 4735
            LAAGDHHKVRVRAHSDHATNELHAPKETNFLVLINVGQYPF
Sbjct: 5158 LAAGDHHKVRVRAHSDHATNELHAPKETNFLVLINVGQYPF 5198



 Score =  424 bits (1089), Expect = e-116
 Identities = 351/1291 (27%), Positives = 547/1291 (42%), Gaps = 61/1291 (4%)
 Frame = +2

Query: 5    SGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHD 184
            +G P P +++ K+G  +N +D   I+     T  I+N Q   +GRYTC A N+ G++  D
Sbjct: 2878 TGTPPPTILFMKDGKRLNESDEVDII---GSTLVIDNPQKEVEGRYTCIAENKAGRSEKD 2934

Query: 185  FSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLT 364
              ++VL PP+         + + GD +TL CPI   ED +   + ++W++     DG L
Sbjct: 2935 MMVEVLLPPKLSKEWINVEV-QAGDPLTLECPI---EDTSG--VHITWSRQF-GKDGQLD 2987

Query: 365  DNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVI---DISRNDV 535
                 S D  KL I QA+ E+A  Y+CIA+N AG A   F+V + +PP I     S  ++
Sbjct: 2988 MRAQSSSDKSKLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEI 3047

Query: 536  QPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGK 715
                 +  P    C   G P P I W  +GK + +   +   +    L+I     +  G+
Sbjct: 3048 VADTTLEIP----CRTEGIPPPEISWFLDGKPILEMPGVTYKQGDLSLRIDNIKPNQEGR 3103

Query: 716  WSCVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKG 895
            ++CVAEN AG  E +  +++  PP V + S+      G   T+ C   GNP P + W K
Sbjct: 3104 YTCVAENKAGRAEQDTYVEISEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKD 3163

Query: 896  GSLIFDSPDGARISLKGARLDIPHLKKT---DVGDYTCQALNAAGTSEASVSVDVLVPPE 1066
            G      P  + +     +L   HL++T   D G YTC A N AG S+ +  V+VLVPP
Sbjct: 3164 G-----EPYTSDLLQFSTKLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEVLVPPR 3218

Query: 1067 INRDGIDMSPRLPAQQSLT--LQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQ 1240
            I     D    L  ++  T  + C   G+PVP + W  NG  +    P          +
Sbjct: 3219 IE----DEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEIEQFNP---------VLH 3265

Query: 1241 INNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVI-SNGGTKQVIEGELAVIECLVEG 1417
            I N + +D+G Y+C A N AG+    + +DV   P   ++  T  ++EGE A IEC ++G
Sbjct: 3266 IRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNIVEGESAKIECKIDG 3325

Query: 1418 YPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYT 1597
            +P P +SWL+ G      +  +     G  L I++A+  D G+Y C ATN  G ++Q +
Sbjct: 3326 HPKPTISWLKGGR--PFNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFK 3383

Query: 1598 LEVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGAD 1777
            + V   P I  +        +G +  L C V G P P ++W   G+D    ++ HTI  +
Sbjct: 3384 VNVYTKPYIDETIDQTPKAVAGGEIILKCPVLGNPTPTVTWK-RGDDAVPNDSRHTIVNN 3442

Query: 1778 GTLHIEK-AEERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIK 1954
              L I     E    Y C A N+AG  T  +  + I  P     G       E     +
Sbjct: 3443 YDLKINSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMD 3502

Query: 1955 CXXXXXXXXXXXXKNG-VPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNAT 2131
            C              G  P+   +    S D   I I   +LSD G+Y C A+N+AG +
Sbjct: 3503 CGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAKLSDGGKYICRASNEAGTSD 3562

Query: 2132 QKTNLNVGVAPK-----IMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTG 2296
                L + V PK     I+  P   V      + L C  SG+PQP + W K+   +  T
Sbjct: 3563 IDLILKILVPPKIDKSNIIGNPLAIVAR---TIYLECPISGIPQPDVIWTKNGMDINMTD 3619

Query: 2297 VDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEV-VPERMNVST 2473
                     ++    ++  +  G YTC A N       D  L V+ PPE  +
Sbjct: 3620 SRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIK 3679

Query: 2474 NPRQTVFLSCN---ATGIPEPV--ISWMRDSNIA---IQNNEKYQILGTTLAIRNVLPDD 2629
                T+ L+C    A  I + V  +SW +DS      + +N      G  L I     ++
Sbjct: 3680 REGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDGRKLTISQASLEN 3739

Query: 2630 DGFYHCIAKSDAGQKIATRKLIVNKP--------SDRP-----APIWVECDEKGKPKKTE 2770
             G Y CIA + AG+     K+ +  P          +P      P  + C   G P  +
Sbjct: 3740 AGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSI 3799

Query: 2771 YMIDRGD--TPDDNPQLLPWKDV-------EDSSLNGSIAYRCMPGPRSSRTVL-LHAAP 2920
              +  G   T D+N +++    V        D +   S       G +    VL +   P
Sbjct: 3800 KWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPP 3859

Query: 2921 QFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDS----KFEIAYSHLKVTL 3088
               VK  N   A+G  + L C+A+G P+P + WAK G LI DS    +  +  + L +
Sbjct: 3860 VVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGSLIFDSPDGARISLKGARLDIPH 3919

Query: 3089 NSTSDSGEYTCMAQNSVGSSTVSAFINV-------DNNILPTPKPSSNQKNVAVITCYER 3247
               +D G+YTC A N+ G+S  S  ++V        + I  +P+  + Q     + C  +
Sbjct: 3920 LKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQS--LTLQCLAQ 3977

Query: 3248 NQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRHSI 3427
             +   + + W  NG  +  +  GI   ++ + + ++  SL   D  +YTC   N
Sbjct: 3978 GKPVPQ-MRWTLNGTALTHSTPGITVASDSTFIQINNVSL--SDKGVYTCYAENVAGSDN 4034

Query: 3428 PHLTSAFEGVPEVKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLD--DDAIY 3601
                      P +      +V  G+  V++C V   P    V W +N  ++        Y
Sbjct: 4035 LMYNVDVVQAPVISNGGTKQVIEGELAVIECLVEGYP-APQVSWLRNGNRVETGVQGVRY 4093

Query: 3602 XXXXXXXXXXXXEKYDEGVYKCVASNSIGKA 3694
                           D G+Y C A+N  G A
Sbjct: 4094 VTDGRMLTIIEARSLDSGIYLCSATNEAGSA 4124



 Score =  412 bits (1060), Expect = e-113
 Identities = 347/1308 (26%), Positives = 555/1308 (41%), Gaps = 63/1308 (4%)
 Frame = +2

Query: 2    ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH 181
            ++G P P V W +NG +I          Q N    I N    D+G+Y+C A+N  G A
Sbjct: 3240 VTGRPVPYVTWKRNGKEIE---------QFNPVLHIRNATRADEGKYSCIASNEAGTAVA 3290

Query: 182  DFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDL 361
            DF +DV + P F+ H T   I  EG++  + C I            +SW K  R  +
Sbjct: 3291 DFLIDVFTKPTFETHETTFNIV-EGESAKIECKID-----GHPKPTISWLKGGRPFN--- 3341

Query: 362  TDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQP 541
             DN+ +S  G  L I +A   + GLYTC+A N  G++  +FKV + + P ID    D  P
Sbjct: 3342 MDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYID-ETIDQTP 3400

Query: 542  QVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWS 721
            +       I++C V G+P P++ W +    V +D    IV     L+I    ++ AG++S
Sbjct: 3401 KAVAGGEIILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNNYD-LKINSVTTEDAGQYS 3459

Query: 722  CVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKAL-GETITLFCNASGNPYPQLKWAKGG 898
            C+A N+AG        +V   P    K  N  + +  +TIT+ C  +  P P + W +G
Sbjct: 3460 CIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPSISWFRGD 3519

Query: 899  SLIF------DSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVP 1060
              ++       SPDG+ I++  A+L       +D G Y C+A N AGTS+  + + +LVP
Sbjct: 3520 KPVYLYDRYSISPDGSHITINKAKL-------SDGGKYICRASNEAGTSDIDLILKILVP 3572

Query: 1061 PEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQ 1240
            P+I++  I  +P     +++ L+C   G P P + WT NG  +  +   + +A ++
Sbjct: 3573 PKIDKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFG 3632

Query: 1241 INNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVI--EGELAVIECLVE 1414
            I NV ++D+G YTC A N  G  +  +++DV+  P     GT+  I  EG+   + C ++
Sbjct: 3633 IENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIK 3692

Query: 1415 -----GYPAPQVSWLRNGNRVETGV-QGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAG 1576
                       VSW ++   ++  +   V    DGR LTI +A   ++G+Y C A N AG
Sbjct: 3693 LAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDGRKLTISQASLENAGLYTCIALNRAG 3752

Query: 1577 SAQQAYTLEVLVSPKIITSTPGVLTP--SSGSKFSLPCAVRGYPDPIISWTLNGNDIKDG 1750
             A   + +E+L SP +I  +   + P  +      + CAV G+P P I W  NG ++ D
Sbjct: 3753 EASLEFKVEIL-SPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDD 3811

Query: 1751 ENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYING 1927
            EN   +     L I + +  H   + C A+NDAG   LE  +     P +S   +  I
Sbjct: 3812 ENIRIVEQGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKA 3871

Query: 1928 SEGTETVIKCXXXXXXXXXXXXKNGVPLLPSNNLIF-SEDYKLIKILSTRL-------SD 2083
               T T+               K G       +LIF S D   I +   RL       +D
Sbjct: 3872 LGETITLFCNASGNPYPQLKWAKGG-------SLIFDSPDGARISLKGARLDIPHLKKTD 3924

Query: 2084 QGEYSCTAANKAGNATQKTNLNVGVAPKIME-----RPRTQVVHKGDQVTLWCEASGVPQ 2248
             G+Y+C A N AG +    +++V V P+I        PR   +     +TL C A G P
Sbjct: 3925 VGDYTCQALNAAGTSEASVSVDVLVPPEINRDGIDMSPR---LPAQQSLTLQCLAQGKPV 3981

Query: 2249 PAITWYKDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIV 2428
            P + W  +   LT++    T  +    +  +++S S  GVYTC AEN VA ++  +  +
Sbjct: 3982 PQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAEN-VAGSDNLMYNVD 4040

Query: 2429 MIPPEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSN---IAIQNNEKYQILGTT 2599
            ++   V+           +   + C   G P P +SW+R+ N     +Q   +Y   G
Sbjct: 4041 VVQAPVISNGGTKQVIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQ-GVRYVTDGRM 4099

Query: 2600 LAIRNVLPDDDGFYHCIAKSDAG--------QKIATRKLIVNKPS----DRPAPIWVECD 2743
            L I      D G Y C A ++AG        + + + K+I + P        +   + C
Sbjct: 4100 LTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCA 4159

Query: 2744 EKGKPKK-TEYMIDRGDTPDDNPQLLPWKDVE---DSSLNGSIAYRCMPGPRSSRTVLLH 2911
             +G P     + ++  D  D         D     + +    + Y C      +    L
Sbjct: 4160 VRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKAEERHLIYEC-TAKNDAGADTLE 4218

Query: 2912 AAPQFIVKPKNTTA-------AIGAIVELRCSAAGPPHPTITWAKDGKLIEDSK---FEI 3061
               Q IV PK +T+       + G    ++C          +W+K+G  +  S    F
Sbjct: 4219 FPVQTIVAPKISTSGNRYINGSEGTETVIKCEIES-ESSEFSWSKNGVPLLPSNNLIFSE 4277

Query: 3062 AYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVD--NNILPTPKPSSNQKNVAVIT 3235
             Y  +K+     SD GEY+C A N  G++T    +NV     I+  P+     K   V
Sbjct: 4278 DYKLIKILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTL 4337

Query: 3236 CYERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRR 3415
              E +      +TW Y    +  N  G+          +  SS+      +YTCK  N
Sbjct: 4338 WCEASGVPQPAITW-YKDNELLTN-TGVDETATTKKKSVIFSSISPSQAGVYTCKAENWV 4395

Query: 3416 RHSIPHLTSAFEGVPE-VKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDD 3592
              +   +       PE V     V  N   +V L C  T  P    + W ++    + ++
Sbjct: 4396 ASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFLSCNATGIPEPV-ISWMRDSNIAIQNN 4454

Query: 3593 AIYXXXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNVYGGSSR 3736
              Y               D+G Y C+A +  G+     +L V   S R
Sbjct: 4455 EKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVNKPSDR 4502



 Score =  392 bits (1006), Expect = e-107
 Identities = 322/1299 (24%), Positives = 552/1299 (41%), Gaps = 59/1299 (4%)
 Frame = +2

Query: 2    ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH 181
            ++G P P V WTK+G  +    S  +L++  + F I + ++  +G Y C A N  G A
Sbjct: 2122 VTGKPNPVVTWTKDGRPVGDLKSVQVLSEGQQ-FKIVHAEIAHKGSYICMAKNDVGTAEI 2180

Query: 182  DFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDL 361
             F +D+++ P             +G  +   CPI   ++   Q++   W ++ + +D +
Sbjct: 2181 SFDVDIITRPMIQKGIKNIVTAIKGGALPFKCPIDDDKNFKGQII---WLRNYQPIDLEA 2237

Query: 362  TD-NVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQ 538
             D  +    + R+LTI   +  + G Y+C   N AGE S +FK  +L PP I +   D
Sbjct: 2238 EDARITRLSNDRRLTILNVTENDEGQYSCRVKNDAGENSFDFKATVLVPPTIIMLDKDKN 2297

Query: 539  PQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQV----LQILRTDSDH 706
                 +    + C  TG P P I W K+G+ +  +    I+  G++    L+I R
Sbjct: 2298 KTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGELNGNQLKITRIKEGD 2357

Query: 707  AGKWSCVAENDAGVKELEMVLDVFTPPVVS---VKSDNPIKALGETITLFCNASGNPYPQ 877
            AGK++C A+N AG  E ++ ++V T P +    + SD   +   E + + C     P  +
Sbjct: 2358 AGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQ-NERVVISCPVYARPPAK 2416

Query: 878  LKWAKGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLV 1057
            + W K G  +  S    + S  G +L +  L++TD   YTC A N AGT +    V +LV
Sbjct: 2417 ITWLKAGKPL-QSDKFVKTSANGQKLYLFKLRETDSSKYTCIATNEAGTDKRDFKVSMLV 2475

Query: 1058 PPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFI 1237
             P  +   I     + +    TL C A+G P P + W  +G A+  +   +   +    +
Sbjct: 2476 APSFDEPNIVRRITVNSGNPSTLHCPAKGSPSPTITWLKDGNAIEPNDRYVFFDAGRQ-L 2534

Query: 1238 QINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQV--IEGELAVIECLV 1411
            QI+    SD+G YTC A N  GSD+L   ++V+  PVI     + V  IEG  + + C
Sbjct: 2535 QISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIPPVIDGERREAVAVIEGFSSELFC-D 2593

Query: 1412 EGYPAPQVSWLRNGNRVET----GVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGS 1579
                   V W ++G  +      G   ++  + G+ ++ + AR  DSG Y C   N AG
Sbjct: 2594 SNSTGVDVEWQKDGLTINQDTLRGDSFIQIPSSGKKMSFLSARKSDSGRYTCIVRNPAGE 2653

Query: 1580 AQQAYTLEVLVSPKIIT--STPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGE 1753
            A++ +   V   P I    S+  + T        + C V G P P + W  +   ++
Sbjct: 2654 ARKLFDFAVNDPPSISDELSSANIQTIVPYYPVEINCVVSGSPHPKVYWLFDDKPLEPDS 2713

Query: 1754 NGHTIGADG-TLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYING 1927
              + +  +G TL I +++  H   Y C A+N+ G    +F V+    P         +
Sbjct: 2714 AAYELTNNGETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLVRVTAPPHFEKEREEVV-A 2772

Query: 1928 SEGTETVIKCXXXXXXXXXXXXKNGVPLLPSNNLIFSE---DYKLIKILSTRLSDQGEYS 2098
              G   ++ C             +       N +I S+   + K + + + +L D+G Y
Sbjct: 2773 RVGDTMLLTCNAESSVPLSSVYWHAHDESVQNGVITSKYAANEKTLNVTNIQLDDEGFYY 2832

Query: 2099 CTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNE 2278
            CTA N+AG   +   L V   P  +++ +   +  G ++TL C A+G P P I + KD +
Sbjct: 2833 CTAVNEAGITKKFFKLIVIETPYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGK 2892

Query: 2279 LLTNTG-VDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPE 2455
             L  +  VD   +T    ++  +      G YTC AEN    +E+D+ + V++PP++  E
Sbjct: 2893 RLNESDEVDIIGST----LVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKE 2948

Query: 2456 RMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILG--TTLAIRNVLPDD 2629
             +NV       + L C         I+W R      Q + + Q     + L I    P+D
Sbjct: 2949 WINVEVQAGDPLTLECPIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSKLYIMQATPED 3008

Query: 2630 DGFYHCIAKSDAGQKIATRKLIVNKPSD------------RPAPIWVECDEKG-KPKKTE 2770
               Y CIA +DAG   A  ++ VN P                  + + C  +G  P +
Sbjct: 3009 ADSYSCIAVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEIS 3068

Query: 2771 YMIDRGDTPDDNPQLLPWKD----VEDSSLNGSIAYRCMPGPRSSRT-----VLLHAAPQ 2923
            + +D     +         D    +++   N    Y C+   ++ R      V +   P+
Sbjct: 3069 WFLDGKPILEMPGVTYKQGDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEISEPPR 3128

Query: 2924 FIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGK-----LIEDSKFEIAYSHLKVTL 3088
             ++  +      G    +RC   G P P + W KDG+     L++ S  +++Y HL+ T
Sbjct: 3129 VVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKDGEPYTSDLLQFST-KLSYLHLRET- 3186

Query: 3089 NSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQK-------NVAVITCYER 3247
             + +D G YTC+A N  G S  +     D  +L  P+    ++       N  ++ C
Sbjct: 3187 -TLADGGTYTCIATNKAGESQTTT----DVEVLVPPRIEDEERVLQGKEGNTYMVHCQVT 3241

Query: 3248 NQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRHSI 3427
             +     +TW+ NG  + +    +H  N               D   Y+C   N    ++
Sbjct: 3242 GRPVPY-VTWKRNGKEIEQFNPVLHIRN-----------ATRADEGKYSCIASNEAGTAV 3289

Query: 3428 PHLTSAFEGVPEVKTIDKV-EVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIYX 3604
                      P  +T +    +  G+S  ++C++   P  T + W K  +    D+ I
Sbjct: 3290 ADFLIDVFTKPTFETHETTFNIVEGESAKIECKIDGHPKPT-ISWLKGGRPFNMDNIILS 3348

Query: 3605 XXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNVY 3721
                       +++D G+Y CVA+NS G +  D ++NVY
Sbjct: 3349 PRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVY 3387



 Score =  379 bits (973), Expect = e-103
 Identities = 346/1299 (26%), Positives = 550/1299 (41%), Gaps = 70/1299 (5%)
 Frame = +2

Query: 2    ISGIPQPDVIWTKNG--MDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKA 175
            +SG P P + W  +G  ++         L+ +  T   ++V V  +G Y C A ++G
Sbjct: 1573 VSGFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQEGNYHCVAQSKGNIL 1632

Query: 176  SHDFSLDVLSPPEFDIHGTQPTIKRE-GDTITLTCPIKLAEDIADQVMDVSWTKDSRALD 352
              D  L VL+ P   I G    ++   G  I+L+C ++   D  D+   V W+ +    +
Sbjct: 1633 DIDVELSVLAVP---IVGEDDNLEVFLGKDISLSCDLQTESD--DKTTFV-WSINGS--E 1684

Query: 353  GDLTDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRND 532
             D  DNV I  DG +L I+ A  EN G Y C   N AG+A     +++L PPV      +
Sbjct: 1685 SDRPDNVQIPSDGHRLYITDAKPENNGKYMCRVTNSAGKAERTLTLDVLEPPVFVEPVFE 1744

Query: 533  VQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAG 712
               ++  N P I++C VTG+P P++ W  +G +V  D++    E   +L+I +     A
Sbjct: 1745 ANQKLIGNNPIILQCQVTGNPKPTVIWKIDGNDV--DKSWLFDESLSLLRIEKLTGKSA- 1801

Query: 713  KWSCVAENDAGVKELEMVLDVFTPPVVSVKSD-NPIKALGETITLFCNASGNPYPQLKWA 889
            + SC AEN AG    +  +     P    + D   I    ETITL C  S   + Q+ W
Sbjct: 1802 QISCTAENKAGTASRDFFIQNIAAPTFKNEGDQETIFRESETITLDCPVSLGDF-QITWM 1860

Query: 890  KGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEI 1069
            K G  +  + + A  +L   RL I +  +     YTC A N AG       V V V P+I
Sbjct: 1861 KQGLPL--TENDAIFTLDNTRLTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQVLPKI 1918

Query: 1070 NRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINN 1249
                + +   +   + + L C A+G P P  +W  N   L      + V ++ T + +NN
Sbjct: 1919 KNAVVTL--EINEGEEIILTCDAEGNPTPTAKWDFNQGDLPKE--AVFVNNNHTVV-VNN 1973

Query: 1250 VSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVIEGELA---VIECLVEGY 1420
            V+    GVY CYA N  G      NV V   P   +G T+  +   L     +EC V+
Sbjct: 1974 VTKYHTGVYKCYATNKVGQAVKTINVHVRTKPRFESGLTESELTVNLTRSITLECDVDDA 2033

Query: 1421 PAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTL 1600
                +SW  NG        GV+ +  GR L I+ A++ D G Y C+ TNEAG A + + L
Sbjct: 2034 IGVGISWTVNGKPFLAETDGVQTLAGGRFLHIVSAKTDDHGSYACTVTNEAGVATKTFNL 2093

Query: 1601 EVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADG 1780
             V V P I+ +  G  T    +   LPC V G P+P+++WT +G  + D ++   +
Sbjct: 2094 FVQVPPTIV-NEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEGQ 2152

Query: 1781 TLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKC 1957
               I  AE  H   Y C AKND G   + F V  I  P I       +   +G     KC
Sbjct: 2153 QFKIVHAEIAHKGSYICMAKNDVGTAEISFDVDIITRPMIQKGIKNIVTAIKGGALPFKC 2212

Query: 1958 ---XXXXXXXXXXXXKNGVPL---LPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKA 2119
                           +N  P+        +    + + + IL+   +D+G+YSC   N A
Sbjct: 2213 PIDDDKNFKGQIIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTENDEGQYSCRVKNDA 2272

Query: 2120 GNATQKTNLNVGVAPKI--MERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNT 2293
            G  +      V V P I  +++ + +   +   VTL C A+G P+P ITW+KD E +
Sbjct: 2273 GENSFDFKATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIE 2332

Query: 2294 GVDE---TATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERM- 2461
             + +           +  + I    AG YTC+A+N   S E+D+++ V+  P++  + +
Sbjct: 2333 NIADIIPNGELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIP 2392

Query: 2462 -NVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNE--KYQILGTTLAIRNVLPDDD 2632
             +  +   + V +SC     P   I+W++ +   +Q+++  K    G  L +  +   D
Sbjct: 2393 SDYESQQNERVVISCPVYARPPAKITWLK-AGKPLQSDKFVKTSANGQKLYLFKLRETDS 2451

Query: 2633 GFYHCIAKSDAGQKIATRK--LIVNKPSDRP-----------APIWVECDEKGKPKKTEY 2773
              Y CIA ++AG      K  ++V    D P            P  + C  KG P  T
Sbjct: 2452 SKYTCIATNEAGTDKRDFKVSMLVAPSFDEPNIVRRITVNSGNPSTLHCPAKGSPSPTIT 2511

Query: 2774 MIDRGDTPDDNPQLL---PWKDVEDSSLNGSI--AYRCMP----GPRSSRTVLLHAAPQF 2926
             +  G+  + N + +     + ++ S   GS    Y C+     G       L    P
Sbjct: 2512 WLKDGNAIEPNDRYVFFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIPPV 2571

Query: 2927 IVKPKNTTAAI--GAIVELRCSAAGPPHPTITWAKDGKLIE------DSKFEIAYSHLKV 3082
            I   +    A+  G   EL C  +      + W KDG  I       DS  +I  S  K+
Sbjct: 2572 IDGERREAVAVIEGFSSELFCD-SNSTGVDVEWQKDGLTINQDTLRGDSFIQIPSSGKKM 2630

Query: 3083 TLNST--SDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITCY---ER 3247
            +  S   SDSG YTC+ +N  G +      +   N  P+     +  N+  I  Y   E
Sbjct: 2631 SFLSARKSDSGRYTCIVRNPAGEA--RKLFDFAVNDPPSISDELSSANIQTIVPYYPVEI 2688

Query: 3248 NQAYSRG----LTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNR- 3412
            N   S      + W ++  P+  + A     NNG  + +  S ++      YTC+ +N
Sbjct: 2689 NCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIVRSQVEHAG--TYTCEAQNNV 2746

Query: 3413 ---RRHSIPHLTSA--FEGVPEVKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQK 3577
               R+  +  +T+   FE     K  ++V    GD+++L C   S    + V W  +D+
Sbjct: 2747 GKARKDFLVRVTAPPHFE-----KEREEVVARVGDTMLLTCNAESSVPLSSVYWHAHDES 2801

Query: 3578 MLDD--DAIYXXXXXXXXXXXXEKYDEGVYKCVASNSIG 3688
            + +    + Y            +  DEG Y C A N  G
Sbjct: 2802 VQNGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAG 2840



 Score =  364 bits (935), Expect = 1e-98
 Identities = 332/1310 (25%), Positives = 538/1310 (40%), Gaps = 75/1310 (5%)
 Frame = +2

Query: 14   PQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSL 193
            P   + W K G  +  +D  V  + N +   +  ++ TD  +YTC ATN  G    DF +
Sbjct: 2413 PPAKITWLKAGKPLQ-SDKFVKTSANGQKLYLFKLRETDSSKYTCIATNEAGTDKRDFKV 2471

Query: 194  DVLSPPEFDIHGTQPTIKRE-----GDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGD 358
             +L  P FD    +P I R      G+  TL CP K           ++W KD  A++ +
Sbjct: 2472 SMLVAPSFD----EPNIVRRITVNSGNPSTLHCPAK-----GSPSPTITWLKDGNAIEPN 2522

Query: 359  LTDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQ 538
              D     D GR+L IS+    + G YTCIA N  G   LE  +E++ PPVID  R +
Sbjct: 2523 --DRYVFFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIPPVIDGERREAV 2580

Query: 539  PQV-AVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDD-----ENIRIVEQGQVLQILRTDS 700
              +   +         TG     ++W K+G  +  D       I+I   G+ +  L
Sbjct: 2581 AVIEGFSSELFCDSNSTG---VDVEWQKDGLTINQDTLRGDSFIQIPSSGKKMSFLSARK 2637

Query: 701  DHAGKWSCVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLF------CNASG 862
              +G+++C+  N AG         V  PP +S   D    A  +TI  +      C  SG
Sbjct: 2638 SDSGRYTCIVRNPAGEARKLFDFAVNDPPSIS---DELSSANIQTIVPYYPVEINCVVSG 2694

Query: 863  NPYPQLKWAKGGSLIFDS----PDGARISL--KGARLDIPHLKKTDVGDYTCQALNAAGT 1024
            +P+P++ W      +FD     PD A   L   G  L I   +    G YTC+A N  G
Sbjct: 2695 SPHPKVYW------LFDDKPLEPDSAAYELTNNGETLKIVRSQVEHAGTYTCEAQNNVGK 2748

Query: 1025 SEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGK-PVPQMRWTLNGTALTHST 1201
            +     V V  PP   ++  ++  R+    ++ L C A+   P+  + W  +  ++ +
Sbjct: 2749 ARKDFLVRVTAPPHFEKEREEVVARVG--DTMLLTCNAESSVPLSSVYWHAHDESVQNGV 2806

Query: 1202 PGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPV-ISNGGTKQVI 1378
                 A++   + + N+ L D+G Y C A N AG     + + V++ P  +       +I
Sbjct: 2807 ITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIETPYFLDQQKLYPII 2866

Query: 1379 EGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCS 1558
             G+   ++C   G P P + ++++G R+    + V  +  G  L I   +    G Y C
Sbjct: 2867 LGKRLTLDCSATGTPPPTILFMKDGKRLNESDE-VDII--GSTLVIDNPQKEVEGRYTCI 2923

Query: 1559 ATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLN-GN 1735
            A N+AG +++   +EVL+ PK+      V    +G   +L C +       I+W+   G
Sbjct: 2924 AENKAGRSEKDMMVEVLLPPKLSKEWINVEV-QAGDPLTLECPIEDTSGVHITWSRQFGK 2982

Query: 1736 DIKDGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKISTSGN 1912
            D +      +      L+I +A       Y C A NDAG     F V     PKI
Sbjct: 2983 DGQLDMRAQSSSDKSKLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNTPPKIFGDSF 3042

Query: 1913 RYINGSEGTETVIKCXXXXXXXXXXX-XKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQG 2089
                    T   I C              +G P+L    + + +    ++I + + + +G
Sbjct: 3043 STTEIVADTTLEIPCRTEGIPPPEISWFLDGKPILEMPGVTYKQGDLSLRIDNIKPNQEG 3102

Query: 2090 EYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYK 2269
             Y+C A NKAG A Q T + +   P+++       V +G Q T+ CE  G P+P + W K
Sbjct: 3103 RYTCVAENKAGRAEQDTYVEISEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLK 3162

Query: 2270 DNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVV 2449
            D E  T+  +    +TK   +     + +  G YTC A N    ++   D+ V++PP +
Sbjct: 3163 DGEPYTSDLLQ--FSTKLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEVLVPPRIE 3220

Query: 2450 PERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDD 2629
             E   +      T  + C  TG P P ++W R       N ++ +     L IRN    D
Sbjct: 3221 DEERVLQGKEGNTYMVHCQVTGRPVPYVTWKR-------NGKEIEQFNPVLHIRNATRAD 3273

Query: 2630 DGFYHCIAKSDAGQKIA-------------TRKLIVNKPSDRPAPIWVECDEKGKPKKTE 2770
            +G Y CIA ++AG  +A             T +   N      A I  EC   G PK T
Sbjct: 3274 EGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNIVEGESAKI--ECKIDGHPKPTI 3331

Query: 2771 YMIDRGDTP--DDNPQLLPWKDV--------EDSSLNGSIAYRCMPGPRSSRTVLLHAAP 2920
              + +G  P   DN  L P  D          D  L   +A            V ++  P
Sbjct: 3332 SWL-KGGRPFNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKP 3390

Query: 2921 QFIVKPKNTTAAI-GAIVELRCSAAGPPHPTITWAK-DGKLIEDSKFEIAYSH-LKVTLN 3091
                    T  A+ G  + L+C   G P PT+TW + D  +  DS+  I  ++ LK+
Sbjct: 3391 YIDETIDQTPKAVAGGEIILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNNYDLKINSV 3450

Query: 3092 STSDSGEYTCMAQNSVGSSTV---------SAFINVDNNILPTPKPSSNQKNVAVITCYE 3244
            +T D+G+Y+C+A N  G+ T            F+    N+    +  +   +  V +
Sbjct: 3451 TTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPL 3510

Query: 3245 RNQAYSRGLTWEYNGVPMPKNLAGIHFMN-NGSLVILDTSSLKEGDLELYTCKVRNRRRH 3421
             + ++ RG          P  L   + ++ +GS + ++ + L +G    Y C+  N
Sbjct: 3511 PSISWFRG--------DKPVYLYDRYSISPDGSHITINKAKLSDGG--KYICRASNEAG- 3559

Query: 3422 SIPHLTSAFEGVPEVKTIDKVEVNN---------GDSVVLDCEVTSDPLTTHVVWTKN-- 3568
                 TS  + + ++    K++ +N           ++ L+C ++  P    V+WTKN
Sbjct: 3560 -----TSDIDLILKILVPPKIDKSNIIGNPLAIVARTIYLECPISGIP-QPDVIWTKNGM 3613

Query: 3569 DQKMLDDDAIYXXXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNV 3718
            D  M D   I             +  D+G Y C A+N  GKA  D  L+V
Sbjct: 3614 DINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDV 3663



 Score =  362 bits (928), Expect = 6e-98
 Identities = 330/1318 (25%), Positives = 547/1318 (41%), Gaps = 79/1318 (5%)
 Frame = +2

Query: 2    ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH 181
            I G P P + W KNG D+   D  + +  N     I   +  D G Y+C   N  GK
Sbjct: 726  IRGKPHPKIRWFKNGKDLIKPDDYIKI--NEGQLHIMGAKDEDAGAYSCVGENMAGKDVQ 783

Query: 182  DFSLDVLSPPEF--DIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDG 355
              +L V   P      H  +  I+R+   +TL C   LA  I     ++ W K +  L
Sbjct: 784  VANLSVGRVPTIIESPHTVRVNIERQ---VTLQC---LAVGIPPP--EIEWQKGNVLLAT 835

Query: 356  DLTDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDV 535
                      DG  L I+ A +E+ G +TCIA N  G+ S    + +       +
Sbjct: 836  LNNPRYTQLADG-NLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVSPVLGHVPP 894

Query: 536  QPQVAVNQPTIMRCAVT-GHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAG 712
            + Q+   Q   + C V  G P PSI W+K+ K V +   I+I   G +L++   +    G
Sbjct: 895  EEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEG 954

Query: 713  KWSCVAENDAG----------VKELEMVLD-----VFTPPV-------VSVKSDNPIKAL 826
            K++C+A + AG          +K+ E V       VF P +       V+V +
Sbjct: 955  KYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLD 1014

Query: 827  GETITLFCNASGNPYPQLKWAKGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQA 1006
            GE   + C  SG P P + W   G  I  +     ++     L +    K+  G YTCQA
Sbjct: 1015 GEGFAIPCVVSGTPPPIITWYLDGRPITPNSRDFTVTADNT-LIVRKADKSYSGVYTCQA 1073

Query: 1007 LNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTA 1186
             N+AG +E   ++ ++  P I+      S  +      T+ C   G P P + W L+
Sbjct: 1074 TNSAGDNEQKTTIRIMNTPMISPG--QSSFNMVVDDLFTIPCDVYGDPKPVITWLLDDKP 1131

Query: 1187 LTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGT 1366
             T       V ++   + I NV+ + +G +TC+A+N AG+D     + V   P I+
Sbjct: 1132 FTEG-----VVNEDGSLTIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAENQ 1186

Query: 1367 KQV-IEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSG 1543
            +++ ++ +  V+EC  +  P P   W   G ++++ +       DG  L +   +  ++G
Sbjct: 1187 EKIALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDG-ALVLQNVKLENTG 1245

Query: 1544 IYLCSATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWT 1723
            +++C  +N AG    +YTL V   PKII+  PGV+    G    +PC   G P+ I +W
Sbjct: 1246 VFVCQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWN 1305

Query: 1724 LNGNDIKDGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKIS 1900
             NG D+K  E   ++   GTL I +A++  +  Y C   N+AG   +   V     P I
Sbjct: 1306 KNGIDLKMDEKKFSVDNLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHVDVQEPPIIL 1365

Query: 1901 TSGNRYINGSEGTETVIKCXXXXX-XXXXXXXKNGVPLLPSNNLIFSEDYKLIKILSTRL 2077
             S         G    +KC             + G+ +         E    + I S  +
Sbjct: 1366 PSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRGIAIGTDTKGYVVESDGTLVIQSASV 1425

Query: 2078 SDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERP--RTQVVHKGDQVTLWCEASGVPQP 2251
             D   Y+C A+N AG A     + V  +P I +      + + +    +L+C     P P
Sbjct: 1426 EDATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLP 1485

Query: 2252 AITWY-KDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIV 2428
             I+WY  D  L+ +    +T+  K+K  +F +   + +GVY C A N      +   + V
Sbjct: 1486 QISWYLNDKPLIDDKTSWKTSDDKRKLHVFKA-KITDSGVYKCVARNAAGEGSKSFQVEV 1544

Query: 2429 MIPPEVVPE--RMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQIL---- 2590
            ++P  +     +  V     + V L C  +G P P I+W+ D  + ++  +KY+
Sbjct: 1545 IVPLNLDESKYKKKVFAKEGEEVTLGCPVSGFPVPQINWVVDGTV-VEPGKKYKGATLSN 1603

Query: 2591 -GTTLAIRNVLPDDDGFYHCIAKSDA---------------------------GQKIATR 2686
             G TL   +V    +G YHC+A+S                             G+ I+
Sbjct: 1604 DGLTLHFDSVSVKQEGNYHCVAQSKGNILDIDVELSVLAVPIVGEDDNLEVFLGKDISLS 1663

Query: 2687 KLIVNKPSDRPAPIW-VECDEKGKPKKTEYMIDRGDTPDDNPQLLPWKDVEDSSLNGSIA 2863
              +  +  D+   +W +   E  +P       D    P D  +L     + D+    +
Sbjct: 1664 CDLQTESDDKTTFVWSINGSESDRP-------DNVQIPSDGHRLY----ITDAKPENNGK 1712

Query: 2864 YRCM---PGPRSSRTVLLHA-APQFIVKP---KNTTAAIGAIVELRCSAAGPPHPTITWA 3022
            Y C       ++ RT+ L    P   V+P    N        + L+C   G P PT+ W
Sbjct: 1713 YMCRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWK 1772

Query: 3023 KDGKLIEDS-KFEIAYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPK 3199
             DG  ++ S  F+ + S L++    T  S + +C A+N  G+++   FI   N   PT K
Sbjct: 1773 IDGNDVDKSWLFDESLSLLRIE-KLTGKSAQISCTAENKAGTASRDFFI--QNIAAPTFK 1829

Query: 3200 PSSNQKNV----AVITCYERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSL 3367
               +Q+ +      IT           +TW   G+P+ +N A I  ++N  L IL+ +
Sbjct: 1830 NEGDQETIFRESETITLDCPVSLGDFQITWMKQGLPLTENDA-IFTLDNTRLTILNANRD 1888

Query: 3368 KEGDLELYTCKVRNRRRHSIPHLTSAFEGVPEVK-TIDKVEVNNGDSVVLDCEVTSDPLT 3544
             E   ++YTC   N             + +P++K  +  +E+N G+ ++L C+   +P
Sbjct: 1889 HE---DIYTCVANNTAGQVSKDFDVVVQVLPKIKNAVVTLEINEGEEIILTCDAEGNPTP 1945

Query: 3545 THVVWTKNDQKMLDDDAIYXXXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNV 3718
            T   W  N Q  L  +A++             KY  GVYKC A+N +G+A     ++V
Sbjct: 1946 T-AKWDFN-QGDLPKEAVFVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAVKTINVHV 2001



 Score =  354 bits (909), Expect = 1e-95
 Identities = 319/1287 (24%), Positives = 525/1287 (40%), Gaps = 58/1287 (4%)
 Frame = +2

Query: 8    GIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDF 187
            G P P + W K+G  I   D R +         I   + +DQGRYTC ATN  G    +
Sbjct: 2504 GSPSPTITWLKDGNAIEPND-RYVFFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLEN 2562

Query: 188  SLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTD 367
            +L+V+ PP  D    +     EG +  L C      D     +DV W KD   ++ D
Sbjct: 2563 TLEVIIPPVIDGERREAVAVIEGFSSELFC------DSNSTGVDVEWQKDGLTINQDTLR 2616

Query: 368  N---VDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQ 538
                + I   G+K++   A   ++G YTCI  N AGEA   F   +  PP I    +
Sbjct: 2617 GDSFIQIPSSGKKMSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVNDPPSISDELSSAN 2676

Query: 539  PQVAVNQ-PTIMRCAVTGHPFPSIKWLKNGKEVTDDENI-RIVEQGQVLQILRTDSDHAG 712
             Q  V   P  + C V+G P P + WL + K +  D     +   G+ L+I+R+  +HAG
Sbjct: 2677 IQTIVPYYPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIVRSQVEHAG 2736

Query: 713  KWSCVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGN-PYPQLKWA 889
             ++C A+N+ G    + ++ V  PP    + +  +  +G+T+ L CNA  + P   + W
Sbjct: 2737 TYTCEAQNNVGKARKDFLVRVTAPPHFEKEREEVVARVGDTMLLTCNAESSVPLSSVYWH 2796

Query: 890  KGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEI 1069
                 + +    ++ +     L++ +++  D G Y C A+N AG ++    + V+  P
Sbjct: 2797 AHDESVQNGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIETPYF 2856

Query: 1070 NRDGIDMSPRLPA--QQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQI 1243
                +D     P    + LTL C A G P P + +  +G  L  S     + S    + I
Sbjct: 2857 ----LDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDIIGST---LVI 2909

Query: 1244 NNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTK-QVIEGELAVIECLVEGY 1420
            +N     +G YTC AEN AG       V+V+  P +S      +V  G+   +EC +E
Sbjct: 2910 DNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLECPIEDT 2969

Query: 1421 PAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTL 1600
                ++W R   +        +  +D   L I++A   D+  Y C A N+AG A+  + +
Sbjct: 2970 SGVHITWSRQFGKDGQLDMRAQSSSDKSKLYIMQATPEDADSYSCIAVNDAGGAEAVFQV 3029

Query: 1601 EVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADG 1780
             V   PKI   +       + +   +PC   G P P ISW L+G  I +         D
Sbjct: 3030 TVNTPPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFLDGKPILEMPGVTYKQGDL 3089

Query: 1781 TLHIEKAE-ERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKC 1957
            +L I+  +  +   Y C A+N AG    +  V+    P++    +  +   EG +T I+C
Sbjct: 3090 SLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEISEPPRV-VMASEVMRVVEGRQTTIRC 3148

Query: 1958 XXXXXXXXXXX-XKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQ 2134
                         K+G P   S+ L FS     + +  T L+D G Y+C A NKAG +
Sbjct: 3149 EVFGNPEPVVNWLKDGEPYT-SDLLQFSTKLSYLHLRETTLADGGTYTCIATNKAGESQT 3207

Query: 2135 KTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETAT 2314
             T++ V V P+I +  R     +G+   + C+ +G P P +TW ++ + +
Sbjct: 3208 TTDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEIEQFN------ 3261

Query: 2315 TKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVF 2494
                 +   + + +  G Y+C A N   +   D  + V   P         +    ++
Sbjct: 3262 ---PVLHIRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNIVEGESAK 3318

Query: 2495 LSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQK 2674
            + C   G P+P ISW++       +N      G TL I      D G Y C+A +  G
Sbjct: 3319 IECKIDGHPKPTISWLKGGRPFNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDS 3378

Query: 2675 -------IATRKLIVNKPSDRP-----APIWVECDEKGKPKKTEYMIDRGD--TPDDNPQ 2812
                   + T+  I       P       I ++C   G P  T     RGD   P+D+
Sbjct: 3379 EQDFKVNVYTKPYIDETIDQTPKAVAGGEIILKCPVLGNPTPTVTW-KRGDDAVPNDSRH 3437

Query: 2813 LLPWK-DVEDSSLNGSIA--YRCMPGPRSSRTVLLHAA-----PQFIVKPKNTTAAI-GA 2965
             +    D++ +S+    A  Y C+    +      +AA     P F+ K  N    I
Sbjct: 3438 TIVNNYDLKINSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIEND 3497

Query: 2966 IVELRCSAAGPPHPTITWAKDGK---LIEDSKFEIAYSHLKVTLNSTSDSGEYTCMAQNS 3136
             + + C     P P+I+W +  K   L +        SH+ +     SD G+Y C A N
Sbjct: 3498 TITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAKLSDGGKYICRASNE 3557

Query: 3137 VGSSTVSAFINVDNNILPTPKPSSN--QKNVAVITCYERNQAYSRGLTWEYNGVPMPKNL 3310
             G+S +   + +   ++P     SN     +A++       A +  L    +G+P P  +
Sbjct: 3558 AGTSDIDLILKI---LVPPKIDKSNIIGNPLAIV-------ARTIYLECPISGIPQPDVI 3607

Query: 3311 ---AGIHFMNNGSLVILDTSSLKEG-------DLELYTCKVRNRRRHSIPHLTSAFEGVP 3460
                G+      S VIL  ++   G       D   YTC   NR   +    +      P
Sbjct: 3608 WTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPP 3667

Query: 3461 E--VKTIDKVEVNNGDSVVLDCEV-TSDPLTTHVV---WTKNDQKM---LDDDAIYXXXX 3613
            E  +          GD++ L C +  ++ +   V+   WTK+ + +   L D+
Sbjct: 3668 EFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDG 3727

Query: 3614 XXXXXXXXEKYDEGVYKCVASNSIGKA 3694
                       + G+Y C+A N  G+A
Sbjct: 3728 RKLTISQASLENAGLYTCIALNRAGEA 3754



 Score =  339 bits (870), Expect = 3e-91
 Identities = 345/1334 (25%), Positives = 552/1334 (40%), Gaps = 83/1334 (6%)
 Frame = +2

Query: 14   PQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSL 193
            P P + W  N   +    +    + +     +   ++TD G Y C A N  G+ S  F +
Sbjct: 1483 PLPQISWYLNDKPLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQV 1542

Query: 194  DVLSPPEFDIHGTQPTI-KREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALD-GDLTD 367
            +V+ P   D    +  +  +EG+ +TL CP+         V  ++W  D   ++ G
Sbjct: 1543 EVIVPLNLDESKYKKKVFAKEGEEVTLGCPVS-----GFPVPQINWVVDGTVVEPGKKYK 1597

Query: 368  NVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQV 547
               +S+DG  L     S++  G Y C+A ++     ++ ++ +L+ P++     D   +V
Sbjct: 1598 GATLSNDGLTLHFDSVSVKQEGNYHCVAQSKGNILDIDVELSVLAVPIVG---EDDNLEV 1654

Query: 548  AVNQPTIMRCAVT--GHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWS 721
             + +   + C +        +  W  NG E    +N++I   G  L I     ++ GK+
Sbjct: 1655 FLGKDISLSCDLQTESDDKTTFVWSINGSESDRPDNVQIPSDGHRLYITDAKPENNGKYM 1714

Query: 722  CVAENDAGVKELEMVLDVFTPPV-VSVKSDNPIKALGET-ITLFCNASGNPYPQLKWAKG 895
            C   N AG  E  + LDV  PPV V    +   K +G   I L C  +GNP P + W
Sbjct: 1715 CRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKID 1774

Query: 896  G-----SLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVP 1060
            G     S +FD       SL   R++    K   +   +C A N AGT+     +  +
Sbjct: 1775 GNDVDKSWLFDE------SLSLLRIEKLTGKSAQI---SCTAENKAGTASRDFFIQNIAA 1825

Query: 1061 PEINRDGIDMSPRLPAQQSLTLQCLAQGKPVP----QMRWTLNGTALTHSTPGITVASDS 1228
            P    +G D        +++TL C     PV     Q+ W   G  LT +    T+  D+
Sbjct: 1826 PTFKNEG-DQETIFRESETITLDC-----PVSLGDFQITWMKQGLPLTENDAIFTL--DN 1877

Query: 1229 TFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGG-TKQVIEGELAVIEC 1405
            T + I N +   + +YTC A N AG  +  ++V V   P I N   T ++ EGE  ++ C
Sbjct: 1878 TRLTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQVLPKIKNAVVTLEINEGEEIILTC 1937

Query: 1406 LVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQ 1585
              EG P P   W  + N+ +   + V +V +   + +       +G+Y C ATN+ G A
Sbjct: 1938 DAEGNPTPTAKW--DFNQGDLPKEAV-FVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAV 1994

Query: 1586 QAYTLEVLVSPKIITS-TPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENG- 1759
            +   + V   P+  +  T   LT +     +L C V       ISWT+NG       +G
Sbjct: 1995 KTINVHVRTKPRFESGLTESELTVNLTRSITLECDVDDAIGVGISWTVNGKPFLAETDGV 2054

Query: 1760 HTIGADGTLHIEKAE-ERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEG 1936
             T+     LHI  A+ + H  Y CT  N+AG  T  F +   V P I   G  Y    E
Sbjct: 2055 QTLAGGRFLHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQVPPTIVNEGGEY-TVIEN 2113

Query: 1937 TETVIKCXXXXXXXXXXX-XKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAAN 2113
               V+ C             K+G P+    ++    + +  KI+   ++ +G Y C A N
Sbjct: 2114 NSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEGQQFKIVHAEIAHKGSYICMAKN 2173

Query: 2114 KAGNATQKTNLNVGVAPKIMERPRTQVVH-KGDQVTLWCEASGVP--QPAITWYKDNELL 2284
              G A    ++++   P I +  +  V   KG  +   C        +  I W ++ + +
Sbjct: 2174 DVGTAEISFDVDIITRPMIQKGIKNIVTAIKGGALPFKCPIDDDKNFKGQIIWLRNYQPI 2233

Query: 2285 TNTGVDETAT--TKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVV--P 2452
                 D   T  +  + +   +++ +  G Y+C+ +N       D    V++PP ++
Sbjct: 2234 DLEAEDARITRLSNDRRLTILNVTENDEGQYSCRVKNDAGENSFDFKATVLVPPTIIMLD 2293

Query: 2453 ERMNVSTNPRQTVFLSCNATGIPEPVISWMRDS------NIA--IQNNEKYQILGTTLAI 2608
            +  N +     TV LSC ATG PEP I+W +D       NIA  I N E   + G  L I
Sbjct: 2294 KDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGE---LNGNQLKI 2350

Query: 2609 RNVLPDDDGFYHCIAKSDAG---QKIATRKLIVNK------PSDRPA----------PIW 2731
              +   D G Y C A + AG   Q +    + + K      PSD  +          P++
Sbjct: 2351 TRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQNERVVISCPVY 2410

Query: 2732 VECDEK------GKPKKTEYMIDRGDTPDDNPQLLPWKDVE-DSSLNGSIAYRCMPGPRS 2890
                 K      GKP +++  +    T  +  +L  +K  E DSS    IA       +
Sbjct: 2411 ARPPAKITWLKAGKPLQSDKFVK---TSANGQKLYLFKLRETDSSKYTCIATNEAGTDKR 2467

Query: 2891 SRTVLLHAAPQF----IVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSK-- 3052
               V +  AP F    IV+    T   G    L C A G P PTITW KDG  IE +
Sbjct: 2468 DFKVSMLVAPSFDEPNIVR--RITVNSGNPSTLHCPAKGSPSPTITWLKDGNAIEPNDRY 2525

Query: 3053 -FEIAYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAV 3229
             F  A   L+++    SD G YTC+A NSVGS  +   + V   I+P       ++ VAV
Sbjct: 2526 VFFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLENTLEV---IIPPVIDGERREAVAV 2582

Query: 3230 ITCYERN---QAYSRGLT--WEYNGVPMPKN-LAGIHFMN-NGSLVILDTSSLKEGDLEL 3388
            I  +       + S G+   W+ +G+ + ++ L G  F+    S   +   S ++ D
Sbjct: 2583 IEGFSSELFCDSNSTGVDVEWQKDGLTINQDTLRGDSFIQIPSSGKKMSFLSARKSDSGR 2642

Query: 3389 YTCKVRNRRRHSIPHLTSAFEGVPEVKTIDKVEVNNGDSVV------LDCEVTSDPLTTH 3550
            YTC VRN    +      A    P +   D++   N  ++V      ++C V+  P
Sbjct: 2643 YTCIVRNPAGEARKLFDFAVNDPPSIS--DELSSANIQTIVPYYPVEINCVVSGSP-HPK 2699

Query: 3551 VVWTKNDQKMLDDDAIYXXXXXXXXXXXXEKYDE--GVYKCVASNSIGKAFDDTQLNVYG 3724
            V W  +D+ +  D A Y                E  G Y C A N++GKA  D  + V
Sbjct: 2700 VYWLFDDKPLEPDSAAYELTNNGETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLVRV-- 2757

Query: 3725 GSSRREAYKKENED 3766
              +    ++KE E+
Sbjct: 2758 --TAPPHFEKEREE 2769



 Score =  309 bits (792), Expect = 4e-82
 Identities = 333/1324 (25%), Positives = 536/1324 (40%), Gaps = 97/1324 (7%)
 Frame = +2

Query: 23   DVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVL 202
            ++ WT+ G  +            N T  I +V   D G Y C A N GG ++    LD++
Sbjct: 550  EIRWTRYGATV-FNGPNTERNPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMRLDIM 608

Query: 203  SPPEFDIHGTQPTIK-REGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDI 379
             PP   +         REG  + L+C     E + D   +V W    R L  D      +
Sbjct: 609  EPPSVKVTPQDVYFNMREG--VNLSC-----EAMGDPKPEVHWYFKGRHLLNDY--KYQV 659

Query: 380  SDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQ 559
              D + L I  A+  + G Y C A+++AG+A     + + +PP ++I +N +   V
Sbjct: 660  GQDSKFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKM--MVGRGD 717

Query: 560  PTIMRC-AVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSCVAEN 736
                 C  + G P P I+W KNGK++   ++   + +GQ L I+    + AG +SCV EN
Sbjct: 718  RVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQ-LHIMGAKDEDAGAYSCVGEN 776

Query: 737  DAGVKELEMVLDVFTPPVVSVKSDNPIKA-LGETITLFCNASGNPYPQLKWAKGGSLIFD 913
             AG       L V   P + ++S + ++  +   +TL C A G P P+++W KG  L+
Sbjct: 777  MAGKDVQVANLSVGRVPTI-IESPHTVRVNIERQVTLQCLAVGIPPPEIEWQKGNVLLAT 835

Query: 914  SPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDV--LVPPEINRDGID 1087
              +     L    L I   +  D G +TC A N  G    S ++ V  LV P +    +
Sbjct: 836  LNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVSPVLGH--VP 893

Query: 1088 MSPRLPAQQSLTLQC-LAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLSD 1264
               +L   Q LTL C +  G P P + W  +   +    P I +    + +++   +  D
Sbjct: 894  PEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEG-PTIKIEGGGSLLRLRGGNPKD 952

Query: 1265 KGVYTCYAENVAGSDNLMYNVDVVQAP-----------------------VISNGGTKQV 1375
            +G YTC A + AG+  L  NV +++ P                       V     T  V
Sbjct: 953  EGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDV 1012

Query: 1376 IEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLC 1555
            ++GE   I C+V G P P ++W  +G  +    +    VT    L + +A    SG+Y C
Sbjct: 1013 LDGEGFAIPCVVSGTPPPIITWYLDGRPITPNSRDFT-VTADNTLIVRKADKSYSGVYTC 1071

Query: 1556 SATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSS--GSKFSLPCAVRGYPDPIISWTLN 1729
             ATN AG  +Q  T+ ++ +P I   +PG  + +      F++PC V G P P+I+W L+
Sbjct: 1072 QATNSAGDNEQKTTIRIMNTPMI---SPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLD 1128

Query: 1730 GNDIKDGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKISTS 1906
                 +G     +  DG+L I    E H   + C A+N AG DT    +     P I+
Sbjct: 1129 DKPFTEG----VVNEDGSLTIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAE 1184

Query: 1907 GNRYINGSEGTETVIKCXXXX-----XXXXXXXXKNGVPLLPSNNLIFSEDYKLIKILST 2071
                I   +  + V++C                 K    L+P       ED  L+ + +
Sbjct: 1185 NQEKI-ALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHT---IREDGALV-LQNV 1239

Query: 2072 RLSDQGEYSCTAANKAGNATQKTNLNVGVAPKIM-ERPRTQVVHKGDQVTLWCEASGVPQ 2248
            +L + G + C  +N AG  +    L V   PKI+ E P    V KG  + + C A+GVP+
Sbjct: 1240 KLENTGVFVCQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPE 1299

Query: 2249 PAITWYKDNELLTNTGVDETATTKKKSV-------IFSSISPSQAGVYTCKAENWVASTE 2407
               TW K+       G+D     KK SV       I+ +   +  G Y C   N   +++
Sbjct: 1300 VIRTWNKN-------GIDLKMDEKKFSVDNLGTLRIYEA-DKNDIGNYNCVVTNEAGTSQ 1351

Query: 2408 EDIDLIVMIPPEVVPE-RMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQ 2584
                + V  PP ++P  + N +      V L C     P   ++W R   IAI  + K
Sbjct: 1352 MTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFR-RGIAIGTDTKGY 1410

Query: 2585 ILGT--TLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVNKPSD--RPAPIWVECDEKG 2752
            ++ +  TL I++   +D   Y C A + AG+  A  ++ V    D   P  +  E  ++
Sbjct: 1411 VVESDGTLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESIKES 1470

Query: 2753 KPKKTEYMIDRGDTP------DDNPQL---LPWKDVED--------SSLNGSIAYRCM-- 2875
             P      +     P      +D P +     WK  +D        + +  S  Y+C+
Sbjct: 1471 HPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVAR 1530

Query: 2876 ----PGPRSSRT-VLLHAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLI 3040
                 G +S +  V++          K   A  G  V L C  +G P P I W  DG ++
Sbjct: 1531 NAAGEGSKSFQVEVIVPLNLDESKYKKKVFAKEGEEVTLGCPVSGFPVPQINWVVDGTVV 1590

Query: 3041 EDSK--FEIAYSHLKVTLN----STSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKP 3202
            E  K       S+  +TL+    S    G Y C+AQ    S      I+V+ ++L  P
Sbjct: 1591 EPGKKYKGATLSNDGLTLHFDSVSVKQEGNYHCVAQ----SKGNILDIDVELSVLAVPIV 1646

Query: 3203 SSNQ-------KNVAVITCYERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNG-SLVILDT 3358
              +        K++++    +          W  NG    +    +   ++G  L I D
Sbjct: 1647 GEDDNLEVFLGKDISLSCDLQTESDDKTTFVWSINGSESDRP-DNVQIPSDGHRLYITDA 1705

Query: 3359 SSLKEGDLELYTCKVRN-----RRRHSIPHLTSAFEGVPEVKTIDKVEVNNGDSVVLDCE 3523
                 G    Y C+V N      R  ++  L       P  +   K+  NN   ++L C+
Sbjct: 1706 KPENNGK---YMCRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLIGNN--PIILQCQ 1760

Query: 3524 VTSDPLTTHVVWTKN----DQKMLDDDAIYXXXXXXXXXXXXEKYDEGVYKCVASNSIGK 3691
            VT +P  T V+W  +    D+  L D+++             +        C A N  G
Sbjct: 1761 VTGNPKPT-VIWKIDGNDVDKSWLFDESLSLLRIEKLTGKSAQ------ISCTAENKAGT 1813

Query: 3692 AFDD 3703
            A  D
Sbjct: 1814 ASRD 1817



 Score =  299 bits (766), Expect = 4e-79
 Identities = 288/1154 (24%), Positives = 473/1154 (40%), Gaps = 77/1154 (6%)
 Frame = +2

Query: 542  QVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWS 721
            Q  V +   + C V      +I W+K G+++             V  I       AG++
Sbjct: 439  QEFVGRDLNLSCTVESASAYTIYWVKTGEDIIGGPLFYHNTDTSVWTIPELSLKDAGEYE 498

Query: 722  CVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGS 901
            C   ++ G   ++  ++    P       N    LGE   L C+       +++W + G+
Sbjct: 499  CRVISNNGNYSVKTRVETRESPPEIFGVRNVSVPLGEAAFLHCSTRSAGEVEIRWTRYGA 558

Query: 902  LIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDG 1081
             +F+ P+  R    G  L I H+ + D G Y C A NA G S   + +D++ PP +
Sbjct: 559  TVFNGPNTERNPTNGT-LKIHHVTRADAGVYECMARNAGGMSTRKMRLDIMEPPSVKVTP 617

Query: 1082 IDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLS 1261
             D+   +  ++ + L C A G P P++ W   G  L +      V  DS F+ I + +
Sbjct: 618  QDVYFNM--REGVNLSCEAMGDPKPEVHWYFKGRHLLNDYK-YQVGQDSKFLYIRDATHH 674

Query: 1262 DKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVI-EGELAVIEC-LVEGYPAPQV 1435
            D+G Y C A + AG      ++ +   P +     K ++  G+    EC  + G P P++
Sbjct: 675  DEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKI 734

Query: 1436 SWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVS 1615
             W +NG  +      ++ + +G+ L I+ A+  D+G Y C   N AG   Q   L V
Sbjct: 735  RWFKNGKDLIKPDDYIK-INEGQ-LHIMGAKDEDAGAYSCVGENMAGKDVQVANLSVGRV 792

Query: 1616 PKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENG--HTIGADGTLH 1789
            P II S P  +  +   + +L C   G P P I W   GN +    N   +T  ADG L
Sbjct: 793  PTIIES-PHTVRVNIERQVTLQCLAVGIPPPEIEWQ-KGNVLLATLNNPRYTQLADGNLL 850

Query: 1790 IEKAE-ERHLIYECTAKNDAG--ADTLEFPVQTIVAPKIS--TSGNRYINGSEGTETVIK 1954
            I  A+ E    + C A+N  G  + +    V  +V+P +       + I G + T + +
Sbjct: 851  ITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVSPVLGHVPPEEQLIEGQDLTLSCV- 909

Query: 1955 CXXXXXXXXXXXXKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQ 2134
                         K+  P+     +       L+++      D+G+Y+C A + AGN+T
Sbjct: 910  VVLGTPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEGKYTCIAVSPAGNSTL 969

Query: 2135 KTNLNVGVAPKIMERPRTQVVHK----------------------GDQVTLWCEASGVPQ 2248
              N+ +   P+ + +P   +V K                      G+   + C  SG P
Sbjct: 970  HINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEGFAIPCVVSGTPP 1029

Query: 2249 PAITWYKDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIV 2428
            P ITWY D   +T    D T T    ++I      S +GVYTC+A N     E+   + +
Sbjct: 1030 PIITWYLDGRPITPNSRDFTVTADN-TLIVRKADKSYSGVYTCQATNSAGDNEQKTTIRI 1088

Query: 2429 MIPPEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQN--NEKYQILGTTL 2602
            M  P + P + + +        + C+  G P+PVI+W+ D     +   NE       +L
Sbjct: 1089 MNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLDDKPFTEGVVNE-----DGSL 1143

Query: 2603 AIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVN-----------KPSDRPAPIWVECDEK 2749
             I NV     G + C A++ AG    T  L V+           K + +   I +EC  K
Sbjct: 1144 TIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAENQEKIALQNDDIVLECPAK 1203

Query: 2750 GKPKKTEYMIDRGDTPDDNPQLLPWKDVEDSS-------LNGSIAYRC----MPGPRS-S 2893
              P         G+  D   QL+P    ED +       L  +  + C    + G  S S
Sbjct: 1204 ALPPPVRLWTYEGEKIDS--QLIPHTIREDGALVLQNVKLENTGVFVCQVSNLAGEDSLS 1261

Query: 2894 RTVLLHAAPQFIVK-PKNTTAAIGAIVELRCSAAGPPHPTITWAKDG--KLIEDSKFEI- 3061
             T+ +H  P+ I + P       G  +E+ C A G P    TW K+G    +++ KF +
Sbjct: 1262 YTLTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVD 1321

Query: 3062 AYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVI--- 3232
                L++     +D G Y C+  N  G+S ++  ++V     P   PS+   N AV+
Sbjct: 1322 NLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHVDVQEP--PIILPSTQTNNTAVVGDR 1379

Query: 3233 ---TCYERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKV 3403
                CY    +    +TW   G+ +  +  G    ++G+LVI    S    D  +YTCK
Sbjct: 1380 VELKCYV-EASPPASVTWFRRGIAIGTDTKGYVVESDGTLVI---QSASVEDATIYTCKA 1435

Query: 3404 RNRRRHSIPHLTSAFEGVPEVKTIDKV---EVNNGDSVVLDCEVTSDPLTTHVVWTKNDQ 3574
             N    +  +L       P++K  D V    +       L C V S+PL   + W  ND+
Sbjct: 1436 SNPAGKAEANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPL-PQISWYLNDK 1494

Query: 3575 KMLDDDAIYXXXXXXXXXXXXEK--YDEGVYKCVASNSIGKAFDDTQ------LNVYGGS 3730
             ++DD   +            +    D GVYKCVA N+ G+     Q      LN+
Sbjct: 1495 PLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLNLDESK 1554

Query: 3731 SRREAYKKENEDAS 3772
             +++ + KE E+ +
Sbjct: 1555 YKKKVFAKEGEEVT 1568



 Score =  265 bits (678), Expect = 6e-69
 Identities = 294/1175 (25%), Positives = 469/1175 (39%), Gaps = 79/1175 (6%)
 Frame = +2

Query: 254  GDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGD--LTDNVDISDDGRKLTISQASLEN 427
            G  + L+C ++ A         + W K    + G      N D S      TI + SL++
Sbjct: 443  GRDLNLSCTVESAS-----AYTIYWVKTGEDIIGGPLFYHNTDTS----VWTIPELSLKD 493

Query: 428  AGLYTCIALNRAGEASLEFKVEIL-SPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPS 604
            AG Y C  ++  G  S++ +VE   SPP I   RN     V + +   + C+
Sbjct: 494  AGEYECRVISNNGNYSVKTRVETRESPPEIFGVRN---VSVPLGEAAFLHCSTRSAGEVE 550

Query: 605  IKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTP 784
            I+W + G  V +  N         L+I       AG + C+A N  G+   +M LD+  P
Sbjct: 551  IRWTRYGATVFNGPNTERNPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMRLDIMEP 610

Query: 785  PVVSVKSDNPIKALGETITLFCNASGNPYPQLKW-AKGGSLIFDSPDGARISLKGARLDI 961
            P V V   +    + E + L C A G+P P++ W  KG  L+ D     ++      L I
Sbjct: 611  PSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLLNDYK--YQVGQDSKFLYI 668

Query: 962  PHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQC-LA 1138
                  D G Y C+A++ AG +  +  + +  PP++  + I     +     ++ +C
Sbjct: 669  RDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKV--EIIQNKMMVGRGDRVSFECKTI 726

Query: 1139 QGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLM 1318
            +GKP P++RW  NG  L    P   +  +   + I      D G Y+C  EN+AG D  +
Sbjct: 727  RGKPHPKIRWFKNGKDLI--KPDDYIKINEGQLHIMGAKDEDAGAYSCVGENMAGKDVQV 784

Query: 1319 YNVDVVQAP-VISNGGTKQVIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRY-- 1489
             N+ V + P +I +  T +V       ++CL  G P P++ W + GN +   +   RY
Sbjct: 785  ANLSVGRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEW-QKGNVLLATLNNPRYTQ 843

Query: 1490 VTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEV--LVSPKIITSTPGVLTPSSG 1663
            + DG +L I +A+  D G + C A N  G   Q+ TL V  LVSP ++   P       G
Sbjct: 844  LADGNLL-ITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVSP-VLGHVPPEEQLIEG 901

Query: 1664 SKFSLPC-AVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKAEER-HLIYECTAK 1837
               +L C  V G P P I W  +   +++G      G    L +     +    Y C A
Sbjct: 902  QDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEGKYTCIAV 961

Query: 1838 NDAGADTLEFPVQTIVAPK--------------ISTSGNRYINGSEGTETV-------IK 1954
            + AG  TL   VQ I  P+              IS    +++     T  V       I
Sbjct: 962  SPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEGFAIP 1021

Query: 1955 CXXXXX-XXXXXXXKNGVPLLP-SNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNA 2128
            C              +G P+ P S +   + D  LI +     S  G Y+C A N AG+
Sbjct: 1022 CVVSGTPPPIITWYLDGRPITPNSRDFTVTADNTLI-VRKADKSYSGVYTCQATNSAGDN 1080

Query: 2129 TQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDET 2308
             QKT + +   P I     +  +   D  T+ C+  G P+P ITW  D++  T   V+E
Sbjct: 1081 EQKTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLDDKPFTEGVVNED 1140

Query: 2309 ATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQT 2488
                  S+   +++ +  G +TC A+N   +    + L V   P +  E
Sbjct: 1141 G-----SLTIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAENQEKIALQNDD 1195

Query: 2489 VFLSCNATGIPEPVISWMRDSNIAIQNNEKYQIL-GTTLAIRNVLPDDDGFYHCIAKSDA 2665
            + L C A  +P PV  W  +          + I     L ++NV  ++ G + C   + A
Sbjct: 1196 IVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDGALVLQNVKLENTGVFVCQVSNLA 1255

Query: 2666 GQKIATRKLIVN-KP---SDRPA--------PIWVECDEKGKPKKTEYMIDRG-----DT 2794
            G+   +  L V+ KP   S+ P          I + C   G P+        G     D
Sbjct: 1256 GEDSLSYTLTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDE 1315

Query: 2795 PDDNPQLLPWKDVEDSSLNGSIAYRCM---PGPRSSRTVLLHAAPQFIVKPK---NTTAA 2956
               +   L    + ++  N    Y C+       S  T  +      I+ P    N TA
Sbjct: 1316 KKFSVDNLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAV 1375

Query: 2957 IGAIVELRCSAAGPPHPTITWAKDGKLI-EDSKFEIAYSHLKVTLNSTS--DSGEYTCMA 3127
            +G  VEL+C     P  ++TW + G  I  D+K  +  S   + + S S  D+  YTC A
Sbjct: 1376 VGDRVELKCYVEASPPASVTWFRRGIAIGTDTKGYVVESDGTLVIQSASVEDATIYTCKA 1435

Query: 3128 QNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITCYERNQAYSRGLTWEYNGVPMPKN 3307
             N  G +        + N+  T   S + K+  V+T     +++   L       P+P+
Sbjct: 1436 SNPAGKA--------EANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQ- 1486

Query: 3308 LAGIHFMNNGSLVILDTSSLKEGD----LELYTCKVRNRRRHSIPHLTSAFEG------- 3454
               I +  N   +I D +S K  D    L ++  K+ +   +      +A EG
Sbjct: 1487 ---ISWYLNDKPLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVE 1543

Query: 3455 ------VPEVKTIDKVEVNNGDSVVLDCEVTSDPL 3541
                  + E K   KV    G+ V L C V+  P+
Sbjct: 1544 VIVPLNLDESKYKKKVFAKEGEEVTLGCPVSGFPV 1578


>gi|39596105|emb|CAE69741.1| Hypothetical protein CBG16014
            [Caenorhabditis briggsae]
          Length = 2590

 Score = 2274 bits (5892), Expect = 0.0
 Identities = 1102/1433 (76%), Positives = 1222/1433 (84%), Gaps = 21/1433 (1%)
 Frame = +2

Query: 500  SPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVL 679
            +PP+ID +RN+ QPQVAVNQPTI+RC VTGHPFP+IKWLKNG EVT DENIRIVEQGQ L
Sbjct: 1159 APPIIDTTRNEAQPQVAVNQPTILRCPVTGHPFPTIKWLKNGVEVTSDENIRIVEQGQTL 1218

Query: 680  QILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNAS 859
            QIL TDS HAGKWSCVAENDAGVKELEM+LDVFTPP VSV S+NPIKA+GETITLFCNA+
Sbjct: 1219 QILLTDSAHAGKWSCVAENDAGVKELEMLLDVFTPPKVSVHSENPIKAVGETITLFCNAT 1278

Query: 860  GNPYPQLKWAKGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASV 1039
            GNP PQ+KW KGG++IFDSPDG R+SLKGARLDIPHLKK DVGDYTCQA+NAAGTSE S+
Sbjct: 1279 GNPPPQMKWLKGGAMIFDSPDGPRVSLKGARLDIPHLKKHDVGDYTCQAMNAAGTSEGSI 1338

Query: 1040 SVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVA 1219
            SVDVLVPPEINRDGIDMSPRLPA Q LTL CLAQGKP P+++WTLNGT L  S   IT+
Sbjct: 1339 SVDVLVPPEINRDGIDMSPRLPASQILTLHCLAQGKPPPKIKWTLNGTELKASKE-ITIG 1397

Query: 1220 SDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVIEGELAVI 1399
            +D++FIQINNVSLSDKGVY C+AEN AGSD+LMYNVDVVQAPVISNGGT+QVIEGELAVI
Sbjct: 1398 TDASFIQINNVSLSDKGVYECHAENSAGSDSLMYNVDVVQAPVISNGGTEQVIEGELAVI 1457

Query: 1400 ECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGS 1579
            ECLVEGYPAPQVSWLRNGNRVETGVQGVRY+ +GR LTIIEARSLDSGIYLCSATNEAGS
Sbjct: 1458 ECLVEGYPAPQVSWLRNGNRVETGVQGVRYMAEGRKLTIIEARSLDSGIYLCSATNEAGS 1517

Query: 1580 AQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENG 1759
            AQQAYTLEVLV PKI++  P  LTPSS + FS+PCAVRGYP+PIISWT+NG +I +G  G
Sbjct: 1518 AQQAYTLEVLVFPKIVSVAPETLTPSSNAGFSMPCAVRGYPEPIISWTVNGKNIFNGTMG 1577

Query: 1760 HTIGADGTLHIEKAEERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGT 1939
            + I +DGTLH+EKAE+R + +ECTAKNDAG D LE+ V TI+APKI +SG R +NGSEG
Sbjct: 1578 YKIDSDGTLHVEKAEQRTMTFECTAKNDAGLDHLEYKVHTIIAPKIGSSGVRSLNGSEGE 1637

Query: 1940 ETVIKCXXXXXXXXXXXXKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKA 2119
            +T IKC            KNG PLLPSN + F E    + I STRLSDQGEYSCT ANKA
Sbjct: 1638 QTRIKCDIEADQSEITWTKNGAPLLPSNTIEFQEKKTFVVITSTRLSDQGEYSCTVANKA 1697

Query: 2120 GNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGV 2299
            GNATQ T+LNVGVAPKI+ERP TQVVHKG+QVTLWCEASGVPQP+I+WYKD +LL+NTG+
Sbjct: 1698 GNATQVTSLNVGVAPKILERPSTQVVHKGEQVTLWCEASGVPQPSISWYKDEQLLSNTGI 1757

Query: 2300 DETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNP 2479
            DETATTKKKSVIFSSI+PSQAGVYTCKAENWV +TEED+DLIVMI PEV PERMNVSTNP
Sbjct: 1758 DETATTKKKSVIFSSITPSQAGVYTCKAENWVGATEEDVDLIVMISPEVSPERMNVSTNP 1817

Query: 2480 RQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKS 2659
            RQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFY+CIAKS
Sbjct: 1818 RQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYYCIAKS 1877

Query: 2660 DAGQKIATRKLIVNKPSDRPAPIWVECDEKGKPKKTEYMIDRGDTPDDNPQLLPWKDVED 2839
            DAGQKIATRKLIVNKPSDRPAPIWVECDEKGKPKKTEYMIDRGDTPDDNPQLLPWKDVED
Sbjct: 1878 DAGQKIATRKLIVNKPSDRPAPIWVECDEKGKPKKTEYMIDRGDTPDDNPQLLPWKDVED 1937

Query: 2840 SSLNGSIAYRCMPGPRSSRTVLLHAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITW 3019
            SSLNGSIAYRCMPGPRSSRTVLLHAAPQFIVKPKNTTAA+ A++ELRCSAAGPP+P ITW
Sbjct: 1938 SSLNGSIAYRCMPGPRSSRTVLLHAAPQFIVKPKNTTAAVRAVIELRCSAAGPPNPVITW 1997

Query: 3020 AKDGKLIEDSKFEIAYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPK 3199
            AKDGKLIE+ K EIAYSHLK+ LNSTSDSGEY+C+AQNSVG+STVSAF+NVDN +LPTP
Sbjct: 1998 AKDGKLIENDKTEIAYSHLKLELNSTSDSGEYSCLAQNSVGTSTVSAFVNVDNIVLPTPI 2057

Query: 3200 PSSNQKNVAVITCYERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGD 3379
            P + +KNVA+ITCYE+NQAYSRG+TWEYNG+PMPKNLAGIHFMNNGSLVILDTSSLKEGD
Sbjct: 2058 PMNVKKNVAIITCYEKNQAYSRGVTWEYNGIPMPKNLAGIHFMNNGSLVILDTSSLKEGD 2117

Query: 3380 LELYTCKVRNRRRHSIPHLTSAFEGVPEVKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVW 3559
            L+LYTCKVRNRRRHSIPHL S +E VP VKT+D+VEVNNGDS V+DCEV+SDPLTTHVVW
Sbjct: 2118 LDLYTCKVRNRRRHSIPHLKSVYEEVPSVKTVDRVEVNNGDSTVIDCEVSSDPLTTHVVW 2177

Query: 3560 TKNDQKMLDDDAIYXXXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNVYGG---- 3727
            TKNDQKM+DD+AIY            EKYDEGVYKCVASNSIGKAFDDT+L VY G
Sbjct: 2178 TKNDQKMMDDEAIYVLPNNSLVLLDVEKYDEGVYKCVASNSIGKAFDDTKLTVYDGEITP 2237

Query: 3728 -----SSRREAYKKEN-----------EDASXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 3859
                  S  E  +  N           +D
Sbjct: 2238 LTGSEGSGVEIAEPSNVGVPTRRDTSVDDEEREKQLQMTTTTTTAPDVHTTQPSRVLTIK 2297

Query: 3860 XAKQYPTDDYHEGSANDDGFGPTTQDSLFEFNPPLHPEISVVNT-DCAGTINENGDCVDK 4036
             A ++PT+D ++GSAN   FGPTT D L E    LH + +VV+T DC GTINENGDCVD
Sbjct: 2298 SAPEFPTEDMYDGSANYPEFGPTTHDVLIERQSDLHSQHAVVDTPDCYGTINENGDCVDG 2357

Query: 4037 DGKTHNLKILTGENHCPEGFAMNPHTRICEDLDECAFYQPCDFECINYDGGFQCNCPLGY 4216
            DG  H LKIL+GEN CPEG+A+NP T +CEDLDEC F+ PCDFECIN +G ++C CP GY
Sbjct: 2358 DGTHHRLKILSGENKCPEGYAINPRTNVCEDLDECQFHLPCDFECINTEGSYECRCPPGY 2417

Query: 4217 ELAEEGCRDVNECESVRCEDGKACFNQLGGYECIDDPCPANYSLVDDRYCEPECENCTST 4396
            ELA++GC D+NECESVRCE+G+ACFNQLGGYECI+DPCPANY+LVDDRYCEP CENCT T
Sbjct: 2418 ELADDGCYDINECESVRCEEGRACFNQLGGYECIEDPCPANYTLVDDRYCEPLCENCTLT 2477

Query: 4397 PIQVHMLAIPSGLPISHIATLTAYDKSGRVLNDTTYAISDTGAPLARGRMTSGPFTIKAV 4576
            PIQVHMLAIPSGLP+SHIATLTAYDKSG+VLNDTTY+ISD   P+ RGRM+SGPF I+ V
Sbjct: 2478 PIQVHMLAIPSGLPVSHIATLTAYDKSGKVLNDTTYSISDREGPMGRGRMSSGPFNIREV 2537

Query: 4577 KRGHAQVWTNRVLAAGDHHKVRVRAHSDHATNELHAPKETNFLVLINVGQYPF 4735
            K GHAQVWTNR+LAAGDH KVRVRAHSDHATNELHAPKET FL+LINVGQYPF
Sbjct: 2538 KAGHAQVWTNRILAAGDHRKVRVRAHSDHATNELHAPKETLFLILINVGQYPF 2590



 Score =  322 bits (826), Expect = 4e-86
 Identities = 256/869 (29%), Positives = 375/869 (42%), Gaps = 23/869 (2%)
 Frame = +2

Query: 134  GRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQV 313
            GRYTC A N+ G++  D  ++V  PP+      Q     EG T+TL CPI    +  +
Sbjct: 127  GRYTCIAENKAGRSEKDMIVEVQVPPKMK-QANQTFDVEEGGTLTLECPI----ENPNGA 181

Query: 314  MDVSWTKDSRALDGDLTDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVE 493
              + W  D  A+     +   IS DG KL I QA   +A  YTC A N AG+ S  F V
Sbjct: 182  RVIYWYTD--AIGKVDPNRSQISGDGTKLFIIQAQESDADRYTCRAHNEAGQDSSVFTVN 239

Query: 494  ILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDD-ENIRIVEQG 670
            +L PP I         ++  N    + C  TG P P I WL +GK +     N+R  +
Sbjct: 240  LLKPPTIP-GEAFSTTEIVSNTTMELNCQPTGKPDPEITWLLDGKPILPGMANVRFEDNN 298

Query: 671  QVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFC 850
            + L I        G+++C A+N  G  E +  +++  PP V + SD      G   T+ C
Sbjct: 299  KKLFIDYIKPSQEGRYTCRADNQLGRAEQDTYVEISEPPRVVMASDKMRVVEGRQTTIRC 358

Query: 851  NASGNPYPQLKWAKGGSLIFDSPDGARISLKGARLDIPHLKKT---DVGDYTCQALNAAG 1021
               G P P++ W K G      P  + +     RL   HL++    D G YTC   N AG
Sbjct: 359  EVFGEPEPKVSWLKDG-----EPYTSDLLQHSTRLSYLHLREATLQDGGKYTCIGTNKAG 413

Query: 1022 TSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHST 1201
             +  +  V++LV P I  +  D        + + + C A G P P + W  NG  L
Sbjct: 414  EARTTTEVEILVAPTIEDE--DRVIYGKEGKPVQINCKASGTPYPTITWKKNGKELDEHN 471

Query: 1202 PGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVI-SNGGTKQVI 1378
              +T         I+N +  D G Y+C A N AGS    + +DV   P       T  +I
Sbjct: 472  SVLT---------ISNATREDDGKYSCLATNEAGSAVADFLLDVYTRPSFHPETTTFNII 522

Query: 1379 EGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCS 1558
            EG  A IEC V+G+P P ++WL+ G  +   +  V     G  L I++++ +D+G+Y C
Sbjct: 523  EGHNAKIECKVDGHPKPTITWLKAGRSL--NMNNVILSPRGDTLMILKSKRVDAGLYTCV 580

Query: 1559 ATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGND 1738
            A N  G+ +Q + + V   P I  +        +G K  L C V G P P + W    +D
Sbjct: 581  AENTFGANEQDFKVNVFTKPYIDEAIDQTPKAVAGEKIDLKCPVLGNPTPTVYWKKGDDD 640

Query: 1739 -IKDGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKISTSGN 1912
             I DG++   IG    L I+   E+    Y C A NDAG     + V  I  P     G
Sbjct: 641  IIIDGKHYELIG--DVLRIKTVTEKDTGAYTCVAINDAGQLRTNYAVDVIGKPTFDRKGE 698

Query: 1913 RYINGSEGTETVIKCXXXXXXXXXXXXKNG-VPLLPSNNLIFSEDYKLIKILSTRLSDQG 2089
                  E  +  + C              G   L    +   SED   I I S RLSD G
Sbjct: 699  NIYEVIEDHDITMDCGVTSRPLPNIAWYRGDNALYIQPHYTISEDGSQITINSARLSDGG 758

Query: 2090 EYSCTAANKAGNATQKTNLNVGVAPK-----IMERPRTQVVHKGDQVTLWCEASGVPQPA 2254
            +Y+C A+N+AG++  +  L + V P+     I+  P   V      + L C  +G+PQP
Sbjct: 759  KYTCRASNEAGSSDIEVILRILVPPRIDKSNIIGNPLAIVAR---NIYLECPVTGIPQPE 815

Query: 2255 ITWYKDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMI 2434
            + W KD   +  T          ++     +  + AG YTC A N       D +L V+
Sbjct: 816  VYWTKDGRDINATDSRIIYAQNNETFGIEKVQVTDAGRYTCTAVNRGGRIAHDFNLDVLS 875

Query: 2435 PPEVVPERMNVSTNPR-QTVFLSC---NATGIPEPV--ISWMRDSNIAIQNNEKYQIL-- 2590
            PP     R   +      T+ L+C    A  + + V  +SW +DS +A+   E   +
Sbjct: 876  PPSFDLYRTQPTIKREGDTITLTCPIKTAEDVADQVMDVSWTKDS-VALDGVETDNVHIS 934

Query: 2591 --GTTLAIRNVLPDDDGFYHCIAKSDAGQ 2671
              G  L I      + G Y CIA + AG+
Sbjct: 935  DDGRKLTIDKASLVNAGMYTCIALNRAGE 963



 Score =  322 bits (824), Expect = 7e-86
 Identities = 290/1112 (26%), Positives = 465/1112 (41%), Gaps = 49/1112 (4%)
 Frame = +2

Query: 2    ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH 181
            ++G P P + W KNG+++  +D  + + +  +T  I        G+++C A N  G
Sbjct: 1186 VTGHPFPTIKWLKNGVEVT-SDENIRIVEQGQTLQILLTDSAHAGKWSCVAENDAGVKEL 1244

Query: 182  DFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDL 361
            +  LDV +PP+  +H   P IK  G+TITL C         +    + W K   A+  D
Sbjct: 1245 EMLLDVFTPPKVSVHSENP-IKAVGETITLFC-----NATGNPPPQMKWLKGG-AMIFDS 1297

Query: 362  TDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQP 541
             D   +S  G +L I      + G YTC A+N AG +     V++L PP I+    D+ P
Sbjct: 1298 PDGPRVSLKGARLDIPHLKKHDVGDYTCQAMNAAGTSEGSISVDVLVPPEINRDGIDMSP 1357

Query: 542  QVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWS 721
            ++  +Q   + C   G P P IKW  NG E+   + I I      +QI        G +
Sbjct: 1358 RLPASQILTLHCLAQGKPPPKIKWTLNGTELKASKEITIGTDASFIQINNVSLSDKGVYE 1417

Query: 722  CVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGS 901
            C AEN AG   L   +DV   PV+S      +   GE   + C   G P PQ+ W + G+
Sbjct: 1418 CHAENSAGSDSLMYNVDVVQAPVISNGGTEQV-IEGELAVIECLVEGYPAPQVSWLRNGN 1476

Query: 902  LIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDG 1081
             +     G R   +G +L I   +  D G Y C A N AG+++ + +++VLV P+I
Sbjct: 1477 RVETGVQGVRYMAEGRKLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVFPKI---- 1532

Query: 1082 IDMSPRLPAQQS---LTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNV 1252
            + ++P      S    ++ C  +G P P + WT+NG  + + T G  + SD T     +V
Sbjct: 1533 VSVAPETLTPSSNAGFSMPCAVRGYPEPIISWTVNGKNIFNGTMGYKIDSDGTL----HV 1588

Query: 1253 SLSDKGVYT--CYAENVAGSDNLMYNVDVVQAPVISNGGTKQV--IEGELAVIECLVEGY 1420
              +++   T  C A+N AG D+L Y V  + AP I + G + +   EGE   I+C +E
Sbjct: 1589 EKAEQRTMTFECTAKNDAGLDHLEYKVHTIIAPKIGSSGVRSLNGSEGEQTRIKCDIEA- 1647

Query: 1421 PAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTL 1600
               +++W +NG  +      + +      + I   R  D G Y C+  N+AG+A Q  +L
Sbjct: 1648 DQSEITWTKNGAPLLPS-NTIEFQEKKTFVVITSTRLSDQGEYSCTVANKAGNATQVTSL 1706

Query: 1601 EVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADG 1780
             V V+PKI+   P       G + +L C   G P P ISW       KD +     G D
Sbjct: 1707 NVGVAPKIL-ERPSTQVVHKGEQVTLWCEASGVPQPSISW------YKDEQLLSNTGIDE 1759

Query: 1781 TLHIEK--------AEERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEG 1936
            T   +K           +  +Y C A+N  GA   +  +  +++P++S      ++ +
Sbjct: 1760 TATTKKKSVIFSSITPSQAGVYTCKAENWVGATEEDVDLIVMISPEVSPE-RMNVSTNPR 1818

Query: 1937 TETVIKCXXXXXXXXXXXXKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANK 2116
                + C                 +   NN  +      + I +    D G Y C A +
Sbjct: 1819 QTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYYCIAKSD 1878

Query: 2117 AGN--ATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTN 2290
            AG   AT+K  +N     K  +RP            +W E     +P  T Y  +    +
Sbjct: 1879 AGQKIATRKLIVN-----KPSDRP----------APIWVECDEKGKPKKTEYMIDR--GD 1921

Query: 2291 TGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVS 2470
            T  D       K V  SS++ S A  Y C     +        +++   P+ + +  N +
Sbjct: 1922 TPDDNPQLLPWKDVEDSSLNGSIA--YRC-----MPGPRSSRTVLLHAAPQFIVKPKNTT 1974

Query: 2471 TNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCI 2650
               R  + L C+A G P PVI+W +D  +    N+K +I  + L +      D G Y C+
Sbjct: 1975 AAVRAVIELRCSAAGPPNPVITWAKDGKLI--ENDKTEIAYSHLKLELNSTSDSGEYSCL 2032

Query: 2651 AKSDAGQKIATRKLIV-NKPSDRPAPIWVE-------CDEKGKPKKTEYMIDRGDTPDDN 2806
            A++  G    +  + V N     P P+ V+       C EK +         RG T + N
Sbjct: 2033 AQNSVGTSTVSAFVNVDNIVLPTPIPMNVKKNVAIITCYEKNQ------AYSRGVTWEYN 2086

Query: 2807 PQLLPWKDVEDSSL--NGSIA--------------YRCMPGPRSSRTVLLHAAPQFIVKP 2938
               +P K++       NGS+               Y C    R   ++    +    V
Sbjct: 2087 GIPMP-KNLAGIHFMNNGSLVILDTSSLKEGDLDLYTCKVRNRRRHSIPHLKSVYEEVPS 2145

Query: 2939 KNTTAAI----GAIVELRCSAAGPPHPT-ITWAK-DGKLIEDSKFEIAYSHLKVTLN-ST 3097
              T   +    G    + C  +  P  T + W K D K+++D    +  ++  V L+
Sbjct: 2146 VKTVDRVEVNNGDSTVIDCEVSSDPLTTHVVWTKNDQKMMDDEAIYVLPNNSLVLLDVEK 2205

Query: 3098 SDSGEYTCMAQNSVGSSTVSAFINV-DNNILP 3190
             D G Y C+A NS+G +     + V D  I P
Sbjct: 2206 YDEGVYKCVASNSIGKAFDDTKLTVYDGEITP 2237



 Score =  290 bits (741), Expect = 3e-76
 Identities = 216/731 (29%), Positives = 326/731 (44%), Gaps = 15/731 (2%)
 Frame = +2

Query: 5    SGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHD 184
            +G P P++ W  +G  I    + V    NN+   I+ ++ + +GRYTC A N+ G+A  D
Sbjct: 269  TGKPDPEITWLLDGKPILPGMANVRFEDNNKKLFIDYIKPSQEGRYTCRADNQLGRAEQD 328

Query: 185  FSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLT 364
              +++  PP   +   +  +  EG   T+ C     E   +    VSW KD      DL
Sbjct: 329  TYVEISEPPRVVMASDKMRVV-EGRQTTIRC-----EVFGEPEPKVSWLKDGEPYTSDLL 382

Query: 365  DNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQ 544
             +   S     L + +A+L++ G YTCI  N+AGEA    +VEIL  P I+     +  +
Sbjct: 383  QH---STRLSYLHLREATLQDGGKYTCIGTNKAGEARTTTEVEILVAPTIEDEDRVIYGK 439

Query: 545  VAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSC 724
                +P  + C  +G P+P+I W KNGKE+         E   VL I     +  GK+SC
Sbjct: 440  --EGKPVQINCKASGTPYPTITWKKNGKELD--------EHNSVLTISNATREDDGKYSC 489

Query: 725  VAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGSL 904
            +A N+AG    + +LDV+T P    ++       G    + C   G+P P + W K G
Sbjct: 490  LATNEAGSAVADFLLDVYTRPSFHPETTTFNIIEGHNAKIECKVDGHPKPTITWLKAGRS 549

Query: 905  IFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDGI 1084
            +  + +   +S +G  L I   K+ D G YTC A N  G +E    V+V   P I+ + I
Sbjct: 550  L--NMNNVILSPRGDTLMILKSKRVDAGLYTCVAENTFGANEQDFKVNVFTKPYID-EAI 606

Query: 1085 DMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLSD 1264
            D +P+  A + + L+C   G P P + W      +        +  D   ++I  V+  D
Sbjct: 607  DQTPKAVAGEKIDLKCPVLGNPTPTVYWKKGDDDIIIDGKHYELIGD--VLRIKTVTEKD 664

Query: 1265 KGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTK--QVIEGELAVIECLVEGYPAPQVS 1438
             G YTC A N AG     Y VDV+  P     G    +VIE     ++C V   P P ++
Sbjct: 665  TGAYTCVAINDAGQLRTNYAVDVIGKPTFDRKGENIYEVIEDHDITMDCGVTSRPLPNIA 724

Query: 1439 WLRNGNRVETGVQGVRYVT-DGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVS 1615
            W R  N +   +Q    ++ DG  +TI  AR  D G Y C A+NEAGS+     L +LV
Sbjct: 725  WYRGDNALY--IQPHYTISEDGSQITINSARLSDGGKYTCRASNEAGSSDIEVILRILVP 782

Query: 1616 PKIITST-PGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADG--TL 1786
            P+I  S   G           L C V G P P + WT +G DI +  +   I A    T
Sbjct: 783  PRIDKSNIIGNPLAIVARNIYLECPVTGIPQPEVYWTKDGRDI-NATDSRIIYAQNNETF 841

Query: 1787 HIEKAEERHL-IYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCXX 1963
             IEK +      Y CTA N  G    +F +  +  P       +     EG    + C
Sbjct: 842  GIEKVQVTDAGRYTCTAVNRGGRIAHDFNLDVLSPPSFDLYRTQPTIKREGDTITLTCPI 901

Query: 1964 XXXXXXX------XXXKNGVPL--LPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKA 2119
                            K+ V L  + ++N+  S+D + + I    L + G Y+C A N+A
Sbjct: 902  KTAEDVADQVMDVSWTKDSVALDGVETDNVHISDDGRKLTIDKASLVNAGMYTCIALNRA 961

Query: 2120 GNATQKTNLNV 2152
            G AT +  + +
Sbjct: 962  GEATLEFKVEI 972



 Score =  280 bits (715), Expect = 3e-73
 Identities = 135/166 (81%), Positives = 149/166 (89%)
 Frame = +2

Query: 2    ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH 181
            ++GIPQP+V WTK+G DIN TDSR+I AQNNETFGIE VQVTD GRYTCTA NRGG+ +H
Sbjct: 808  VTGIPQPEVYWTKDGRDINATDSRIIYAQNNETFGIEKVQVTDAGRYTCTAVNRGGRIAH 867

Query: 182  DFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDL 361
            DF+LDVLSPP FD++ TQPTIKREGDTITLTCPIK AED+ADQVMDVSWTKDS ALDG
Sbjct: 868  DFNLDVLSPPSFDLYRTQPTIKREGDTITLTCPIKTAEDVADQVMDVSWTKDSVALDGVE 927

Query: 362  TDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEIL 499
            TDNV ISDDGRKLTI +ASL NAG+YTCIALNRAGEA+LEFKVEIL
Sbjct: 928  TDNVHISDDGRKLTIDKASLVNAGMYTCIALNRAGEATLEFKVEIL 973



 Score =  262 bits (669), Expect = 7e-68
 Identities = 208/781 (26%), Positives = 334/781 (42%), Gaps = 31/781 (3%)
 Frame = +2

Query: 422  ENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPTIMRCAVTG-HPF 598
            E AG YTCIA N+AG +  +  VE+  PP +  +       V       + C +   +
Sbjct: 124  EAAGRYTCIAENKAGRSEKDMIVEVQVPPKMKQANQTFD--VEEGGTLTLECPIENPNGA 181

Query: 599  PSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVF 778
              I W  +     D    +I   G  L I++     A +++C A N+AG       +++
Sbjct: 182  RVIYWYTDAIGKVDPNRSQISGDGTKLFIIQAQESDADRYTCRAHNEAGQDSSVFTVNLL 241

Query: 779  TPPVVSVKSDNPIKALGET-ITLFCNASGNPYPQLKWAKGGSLIFDSPDGARISLKGARL 955
             PP +  ++ +  + +  T + L C  +G P P++ W   G  I       R      +L
Sbjct: 242  KPPTIPGEAFSTTEIVSNTTMELNCQPTGKPDPEITWLLDGKPILPGMANVRFEDNNKKL 301

Query: 956  DIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCL 1135
             I ++K +  G YTC+A N  G +E    V++  PP +      M  R+   +  T++C
Sbjct: 302  FIDYIKPSQEGRYTCRADNQLGRAEQDTYVEISEPPRVVMASDKM--RVVEGRQTTIRCE 359

Query: 1136 AQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNL 1315
              G+P P++ W  +G   T     +  ++  +++ +   +L D G YTC   N AG
Sbjct: 360  VFGEPEPKVSWLKDGEPYTSDL--LQHSTRLSYLHLREATLQDGGKYTCIGTNKAGEART 417

Query: 1316 MYNVDVVQAPVISNGGTKQVI---EGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVR 1486
               V+++ AP I +    +VI   EG+   I C   G P P ++W +NG  ++
Sbjct: 418  TTEVEILVAPTIED--EDRVIYGKEGKPVQINCKASGTPYPTITWKKNGKELD------- 468

Query: 1487 YVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSSGS 1666
                  +LTI  A   D G Y C ATNEAGSA   + L+V   P     T        G
Sbjct: 469  --EHNSVLTISNATREDDGKYSCLATNEAGSAVADFLLDVYTRPSFHPETT-TFNIIEGH 525

Query: 1667 KFSLPCAVRGYPDPIISW-----TLNGNDIKDGENGHTIGADGTLHIEKAEERHLIYECT 1831
               + C V G+P P I+W     +LN N++     G T+    +  ++       +Y C
Sbjct: 526  NAKIECKVDGHPKPTITWLKAGRSLNMNNVILSPRGDTLMILKSKRVDAG-----LYTCV 580

Query: 1832 AKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCXXXXXXXXXXXXKNGVPL 2011
            A+N  GA+  +F V     P I  + ++      G +  +KC            K G
Sbjct: 581  AENTFGANEQDFKVNVFTKPYIDEAIDQTPKAVAGEKIDLKCPVLGNPTPTVYWKKG--- 637

Query: 2012 LPSNNLIFSEDYKLI----KILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVAPK-IME 2176
               + +I  + Y+LI    +I +    D G Y+C A N AG    +TN  V V  K   +
Sbjct: 638  -DDDIIIDGKHYELIGDVLRIKTVTEKDTGAYTCVAINDAGQL--RTNYAVDVIGKPTFD 694

Query: 2177 RPRTQV--VHKGDQVTLWCEASGVPQPAITWYK-DNELLTNTGVDETATTKKKSVIFSSI 2347
            R    +  V +   +T+ C  +  P P I WY+ DN L        T +     +  +S
Sbjct: 695  RKGENIYEVIEDHDITMDCGVTSRPLPNIAWYRGDNALYIQP--HYTISEDGSQITINSA 752

Query: 2348 SPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNP----RQTVFLSCNATG 2515
              S  G YTC+A N   S++ ++ L +++PP +  ++ N+  NP     + ++L C  TG
Sbjct: 753  RLSDGGKYTCRASNEAGSSDIEVILRILVPPRI--DKSNIIGNPLAIVARNIYLECPVTG 810

Query: 2516 IPEPVISWMRDSN---------IAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAG 2668
            IP+P + W +D           I  QNNE       T  I  V   D G Y C A +  G
Sbjct: 811  IPQPEVYWTKDGRDINATDSRIIYAQNNE-------TFGIEKVQVTDAGRYTCTAVNRGG 863

Query: 2669 Q 2671
            +
Sbjct: 864  R 864



 Score =  257 bits (657), Expect = 2e-66
 Identities = 184/639 (28%), Positives = 285/639 (43%), Gaps = 12/639 (1%)
 Frame = +2

Query: 2    ISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASH 181
            + G P+P V W K+G     T   +  +       +    + D G+YTC  TN+ G+A
Sbjct: 360  VFGEPEPKVSWLKDGEPY--TSDLLQHSTRLSYLHLREATLQDGGKYTCIGTNKAGEART 417

Query: 182  DFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDL 361
               +++L  P  +    +    +EG  + + C              ++W K+ + LD
Sbjct: 418  TTEVEILVAPTIEDED-RVIYGKEGKPVQINCKAS-----GTPYPTITWKKNGKELD--- 468

Query: 362  TDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQP 541
                   +    LTIS A+ E+ G Y+C+A N AG A  +F +++ + P
Sbjct: 469  -------EHNSVLTISNATREDDGKYSCLATNEAGSAVADFLLDVYTRPSFHPETTTFN- 520

Query: 542  QVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWS 721
             +       + C V GHP P+I WLK G+ +  + N+ +  +G  L IL++    AG ++
Sbjct: 521  -IIEGHNAKIECKVDGHPKPTITWLKAGRSLNMN-NVILSPRGDTLMILKSKRVDAGLYT 578

Query: 722  CVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKAL-GETITLFCNASGNPYPQLKWAKGG 898
            CVAEN  G  E +  ++VFT P +    D   KA+ GE I L C   GNP P + W KG
Sbjct: 579  CVAENTFGANEQDFKVNVFTKPYIDEAIDQTPKAVAGEKIDLKCPVLGNPTPTVYWKKGD 638

Query: 899  SLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRD 1078
              I    DG    L G  L I  + + D G YTC A+N AG    + +VDV+  P  +R
Sbjct: 639  DDIII--DGKHYELIGDVLRIKTVTEKDTGAYTCVAINDAGQLRTNYAVDVIGKPTFDRK 696

Query: 1079 GIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSL 1258
            G ++   +     +T+ C    +P+P + W     AL +  P  T++ D + I IN+  L
Sbjct: 697  GENIYEVIE-DHDITMDCGVTSRPLPNIAWYRGDNAL-YIQPHYTISEDGSQITINSARL 754

Query: 1259 SDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNG---GTKQVIEGELAVIECLVEGYPAP 1429
            SD G YTC A N AGS ++   + ++  P I      G    I      +EC V G P P
Sbjct: 755  SDGGKYTCRASNEAGSSDIEVILRILVPPRIDKSNIIGNPLAIVARNIYLECPVTGIPQP 814

Query: 1430 QVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVL 1609
            +V W ++G  +      + Y  +     I + +  D+G Y C+A N  G     + L+VL
Sbjct: 815  EVYWTKDGRDINATDSRIIYAQNNETFGIEKVQVTDAGRYTCTAVNRGGRIAHDFNLDVL 874

Query: 1610 VSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPI-----ISWTLNGN--DIKDGENGHTI 1768
              P              G   +L C ++   D       +SWT +    D  + +N H
Sbjct: 875  SPPSFDLYRTQPTIKREGDTITLTCPIKTAEDVADQVMDVSWTKDSVALDGVETDNVHIS 934

Query: 1769 GADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTI 1882
                 L I+KA   +  +Y C A N AG  TLEF V+ +
Sbjct: 935  DDGRKLTIDKASLVNAGMYTCIALNRAGEATLEFKVEIL 973



 Score =  255 bits (652), Expect = 6e-66
 Identities = 199/779 (25%), Positives = 336/779 (42%), Gaps = 18/779 (2%)
 Frame = +2

Query: 107  IENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIK 286
            I   Q +D  RYTC A N  G+ S  F++++L PP         T      T+ L C
Sbjct: 210  IIQAQESDADRYTCRAHNEAGQDSSVFTVNLLKPPTIPGEAFSTTEIVSNTTMELNC--- 266

Query: 287  LAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDGRKLTISQASLENAGLYTCIALNRAG 466
              +       +++W  D + +   +  NV   D+ +KL I        G YTC A N+ G
Sbjct: 267  --QPTGKPDPEITWLLDGKPILPGMA-NVRFEDNNKKLFIDYIKPSQEGRYTCRADNQLG 323

Query: 467  EASLEFKVEILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDE 646
             A  +  VEI  PP + ++ + +  +V   + T +RC V G P P + WLK+G+  T D
Sbjct: 324  RAEQDTYVEISEPPRVVMASDKM--RVVEGRQTTIRCEVFGEPEPKVSWLKDGEPYTSD- 380

Query: 647  NIRIVEQGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKAL 826
             ++   +   L +        GK++C+  N AG       +++   P +  +
Sbjct: 381  LLQHSTRLSYLHLREATLQDGGKYTCIGTNKAGEARTTTEVEILVAPTIEDEDRVIYGKE 440

Query: 827  GETITLFCNASGNPYPQLKWAKGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQA 1006
            G+ + + C ASG PYP + W K         +G  +    + L I +  + D G Y+C A
Sbjct: 441  GKPVQINCKASGTPYPTITWKK---------NGKELDEHNSVLTISNATREDDGKYSCLA 491

Query: 1007 LNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTA 1186
             N AG++ A   +DV   P  + +    +  +    +  ++C   G P P + W   G +
Sbjct: 492  TNEAGSAVADFLLDVYTRPSFHPETTTFN--IIEGHNAKIECKVDGHPKPTITWLKAGRS 549

Query: 1187 LTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNG-- 1360
            L  +   ++   D+  + I      D G+YTC AEN  G++   + V+V   P I
Sbjct: 550  LNMNNVILSPRGDT--LMILKSKRVDAGLYTCVAENTFGANEQDFKVNVFTKPYIDEAID 607

Query: 1361 GTKQVIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDS 1540
             T + + GE   ++C V G P P V W +  + +   + G  Y   G +L I      D+
Sbjct: 608  QTPKAVAGEKIDLKCPVLGNPTPTVYWKKGDDDII--IDGKHYELIGDVLRIKTVTEKDT 665

Query: 1541 GIYLCSATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISW 1720
            G Y C A N+AG  +  Y ++V+  P        +         ++ C V   P P I+W
Sbjct: 666  GAYTCVAINDAGQLRTNYAVDVIGKPTFDRKGENIYEVIEDHDITMDCGVTSRPLPNIAW 725

Query: 1721 TLNGNDIKDGENGHTIGADG---TLHIEKAEERHLIYECTAKNDAGADTLEFPVQTIVAP 1891
               G++    +  +TI  DG   T++  +  +    Y C A N+AG+  +E  ++ +V P
Sbjct: 726  -YRGDNALYIQPHYTISEDGSQITINSARLSDGGK-YTCRASNEAGSSDIEVILRILVPP 783

Query: 1892 KISTS---GNRYINGSEGTETVIKC-XXXXXXXXXXXXKNGVPL-LPSNNLIFSEDYKLI 2056
            +I  S   GN            ++C             K+G  +    + +I++++ +
Sbjct: 784  RIDKSNIIGNPL--AIVARNIYLECPVTGIPQPEVYWTKDGRDINATDSRIIYAQNNETF 841

Query: 2057 KILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQ--VVHKGDQVTLWCE 2230
             I   +++D G Y+CTA N+ G      NL+V ++P   +  RTQ  +  +GD +TL C
Sbjct: 842  GIEKVQVTDAGRYTCTAVNRGGRIAHDFNLDV-LSPPSFDLYRTQPTIKREGDTITLTCP 900

Query: 2231 ASGVPQPA-----ITWYKDNELLTNTGVDET-ATTKKKSVIFSSISPSQAGVYTCKAEN 2389
                   A     ++W KD+  L     D    +   + +     S   AG+YTC A N
Sbjct: 901  IKTAEDVADQVMDVSWTKDSVALDGVETDNVHISDDGRKLTIDKASLVNAGMYTCIALN 959



 Score =  244 bits (624), Expect = 1e-62
 Identities = 216/873 (24%), Positives = 367/873 (41%), Gaps = 40/873 (4%)
 Frame = +2

Query: 674  VLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCN 853
            +L+IL   S+ AG+++C+AEN AG  E +M+++V  PP +   +       G T+TL C
Sbjct: 116  ILKILE-GSEAAGRYTCIAENKAGRSEKDMIVEVQVPPKMKQANQTFDVEEGGTLTLECP 174

Query: 854  ASGNPYPQLKWAKGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEA 1033
                   ++ +    ++    P+ ++IS  G +L I   +++D   YTC+A N AG   +
Sbjct: 175  IENPNGARVIYWYTDAIGKVDPNRSQISGDGTKLFIIQAQESDADRYTCRAHNEAGQDSS 234

Query: 1034 SVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGIT 1213
              +V++L PP I  +    +  + +  ++ L C   GKP P++ W L+G  +      +
Sbjct: 235  VFTVNLLKPPTIPGEAFS-TTEIVSNTTMELNCQPTGKPDPEITWLLDGKPILPGMANVR 293

Query: 1214 VASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAP-VISNGGTKQVIEGEL 1390
               ++  + I+ +  S +G YTC A+N  G       V++ + P V+      +V+EG
Sbjct: 294  FEDNNKKLFIDYIKPSQEGRYTCRADNQLGRAEQDTYVEISEPPRVVMASDKMRVVEGRQ 353

Query: 1391 AVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNE 1570
              I C V G P P+VSWL++G    + +  +++ T    L + EA   D G Y C  TN+
Sbjct: 354  TTIRCEVFGEPEPKVSWLKDGEPYTSDL--LQHSTRLSYLHLREATLQDGGKYTCIGTNK 411

Query: 1571 AGSAQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDG 1750
            AG A+    +E+LV+P  I     V+    G    + C   G P P I+W  NG ++ +
Sbjct: 412  AGEARTTTEVEILVAP-TIEDEDRVIYGKEGKPVQINCKASGTPYPTITWKKNGKELDEH 470

Query: 1751 ENGHTIGADGTLHIEKAEERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGS 1930
             +  TI            E    Y C A N+AG+   +F +     P        + N
Sbjct: 471  NSVLTIS-------NATREDDGKYSCLATNEAGSAVADFLLDVYTRPSFHPETTTF-NII 522

Query: 1931 EGTETVIKCXXXXXXXXXXXXKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAA 2110
            EG    I+C                  L  NN+I S     + IL ++  D G Y+C A
Sbjct: 523  EGHNAKIECKVDGHPKPTITWLKAGRSLNMNNVILSPRGDTLMILKSKRVDAGLYTCVAE 582

Query: 2111 NKAGNATQKTNLNVGVAPKIMER-PRTQVVHKGDQVTLWCEASGVPQPAITWYK-DNELL 2284
            N  G   Q   +NV   P I E   +T     G+++ L C   G P P + W K D++++
Sbjct: 583  NTFGANEQDFKVNVFTKPYIDEAIDQTPKAVAGEKIDLKCPVLGNPTPTVYWKKGDDDII 642

Query: 2285 TNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMN 2464
             +    E      +     +++    G YTC A N       +  + V+  P    +  N
Sbjct: 643  IDGKHYELIGDVLR---IKTVTEKDTGAYTCVAINDAGQLRTNYAVDVIGKPTFDRKGEN 699

Query: 2465 V-STNPRQTVFLSCNATGIPEPVISWMR-DSNIAIQNNEKYQILGTTLAIRNVLPDDDGF 2638
            +        + + C  T  P P I+W R D+ + IQ +      G+ + I +    D G
Sbjct: 700  IYEVIEDHDITMDCGVTSRPLPNIAWYRGDNALYIQPHYTISEDGSQITINSARLSDGGK 759

Query: 2639 YHCIAKSDAGQ-------------KIATRKLIVNKPSDRPAPIWVECDEKGKPKKTEYMI 2779
            Y C A ++AG              +I    +I N  +     I++EC   G P+   Y
Sbjct: 760  YTCRASNEAGSSDIEVILRILVPPRIDKSNIIGNPLAIVARNIYLECPVTGIPQPEVYWT 819

Query: 2780 DRGDTPDDNPQLLPWKD------VEDSSLNGSIAYRCMPGPRSSR-----TVLLHAAPQF 2926
              G   +     + +        +E   +  +  Y C    R  R      + + + P F
Sbjct: 820  KDGRDINATDSRIIYAQNNETFGIEKVQVTDAGRYTCTAVNRGGRIAHDFNLDVLSPPSF 879

Query: 2927 -IVKPKNTTAAIGAIVELRC-----SAAGPPHPTITWAKDGKL---IEDSKFEIAYSHLK 3079
             + + + T    G  + L C              ++W KD      +E     I+    K
Sbjct: 880  DLYRTQPTIKREGDTITLTCPIKTAEDVADQVMDVSWTKDSVALDGVETDNVHISDDGRK 939

Query: 3080 VTLNSTS--DSGEYTCMAQNSVGSSTVSAFINV 3172
            +T++  S  ++G YTC+A N  G +T+   + +
Sbjct: 940  LTIDKASLVNAGMYTCIALNRAGEATLEFKVEI 972



 Score =  241 bits (616), Expect = 9e-62
 Identities = 209/857 (24%), Positives = 347/857 (40%), Gaps = 48/857 (5%)
 Frame = +2

Query: 986  GDYTCQALNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMR 1165
            G YTC A N AG SE  + V+V VPP++ +   + +  +    +LTL+C  +     ++
Sbjct: 127  GRYTCIAENKAGRSEKDMIVEVQVPPKMKQ--ANQTFDVEEGGTLTLECPIENPNGARVI 184

Query: 1166 WTLNGTALTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAP 1345
            +               ++ D T + I     SD   YTC A N AG D+ ++ V++++ P
Sbjct: 185  YWYTDAIGKVDPNRSQISGDGTKLFIIQAQESDADRYTCRAHNEAGQDSSVFTVNLLKPP 244

Query: 1346 VISNGG--TKQVIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTII 1519
             I      T +++      + C   G P P+++WL +G  +  G+  VR+  + + L I
Sbjct: 245  TIPGEAFSTTEIVSNTTMELNCQPTGKPDPEITWLLDGKPILPGMANVRFEDNNKKLFID 304

Query: 1520 EARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCAVRGY 1699
              +    G Y C A N+ G A+Q   +E+   P+++ ++   +    G + ++ C V G
Sbjct: 305  YIKPSQEGRYTCRADNQLGRAEQDTYVEISEPPRVVMAS-DKMRVVEGRQTTIRCEVFGE 363

Query: 1700 PDPIISWTLNGNDIKDGENGHTIGADGTLHIEKAE-ERHLIYECTAKNDAGADTLEFPVQ 1876
            P+P +SW  +G         H+      LH+ +A  +    Y C   N AG       V+
Sbjct: 364  PEPKVSWLKDGEPYTSDLLQHSTRL-SYLHLREATLQDGGKYTCIGTNKAGEARTTTEVE 422

Query: 1877 TIVAPKISTSGNRYINGSEGTETVIKCXXXXXXXXXXXXKNGVPLLPSNNLIFSEDYKLI 2056
             +VAP I    +R I G EG    I C            K        N     E   ++
Sbjct: 423  ILVAPTIEDE-DRVIYGKEGKPVQINCKASGTPYPTITWK-------KNGKELDEHNSVL 474

Query: 2057 KILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEAS 2236
             I +    D G+YSC A N+AG+A     L+V   P       T  + +G    + C+
Sbjct: 475  TISNATREDDGKYSCLATNEAGSAVADFLLDVYTRPSFHPETTTFNIIEGHNAKIECKVD 534

Query: 2237 GVPQPAITWYKDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDI 2416
            G P+P ITW K    L    V    + +  +++        AG+YTC AEN   + E+D
Sbjct: 535  GHPKPTITWLKAGRSLNMNNV--ILSPRGDTLMILKSKRVDAGLYTCVAENTFGANEQDF 592

Query: 2417 DLIVMIPPEVVPERMNVSTNPR----QTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQ 2584
             + V   P +      +   P+    + + L C   G P P + W +  +  I + + Y+
Sbjct: 593  KVNVFTKPYIDEA---IDQTPKAVAGEKIDLKCPVLGNPTPTVYWKKGDDDIIIDGKHYE 649

Query: 2585 ILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKL-IVNKPS-DRPA----------PI 2728
            ++G  L I+ V   D G Y C+A +DAGQ      + ++ KP+ DR             I
Sbjct: 650  LIGDVLRIKTVTEKDTGAYTCVAINDAGQLRTNYAVDVIGKPTFDRKGENIYEVIEDHDI 709

Query: 2729 WVECDEKGKP---------KKTEYMIDRGDTPDDNPQLLPWKDVEDSSLNGSIAYRCM-- 2875
             ++C    +P             Y+       +D  Q+     +  + L+    Y C
Sbjct: 710  TMDCGVTSRPLPNIAWYRGDNALYIQPHYTISEDGSQI----TINSARLSDGGKYTCRAS 765

Query: 2876 --PGPRSSRTVLLHAAPQFIVKPK---NTTAAIGAIVELRCSAAGPPHPTITWAKDGKLI 3040
               G      +L    P  I K     N  A +   + L C   G P P + W KDG+ I
Sbjct: 766  NEAGSSDIEVILRILVPPRIDKSNIIGNPLAIVARNIYLECPVTGIPQPEVYWTKDGRDI 825

Query: 3041 EDSKFEIAYSHLKVTLN----STSDSGEYTCMAQNSVGSSTVSAFINV----DNNILPTP 3196
              +   I Y+    T        +D+G YTC A N  G       ++V      ++  T
Sbjct: 826  NATDSRIIYAQNNETFGIEKVQVTDAGRYTCTAVNRGGRIAHDFNLDVLSPPSFDLYRTQ 885

Query: 3197 KPSSNQKNVAVITC----YERNQAYSRGLTWEYNGVPMP-KNLAGIHFMNNGSLVILDTS 3361
                 + +   +TC     E        ++W  + V +       +H  ++G  + +D +
Sbjct: 886  PTIKREGDTITLTCPIKTAEDVADQVMDVSWTKDSVALDGVETDNVHISDDGRKLTIDKA 945

Query: 3362 SLKEGDLELYTCKVRNR 3412
            SL      +YTC   NR
Sbjct: 946  SLVNAG--MYTCIALNR 960



 Score =  198 bits (503), Expect = 1e-48
 Identities = 222/872 (25%), Positives = 336/872 (38%), Gaps = 63/872 (7%)
 Frame = +2

Query: 1268 GVYTCYAENVAGSDNLMYNVDVVQAPVISNGG-TKQVIEGELAVIECLVEGYPAPQVSWL 1444
            G YTC AEN AG       V+V   P +     T  V EG    +EC +E     +V +
Sbjct: 127  GRYTCIAENKAGRSEKDMIVEVQVPPKMKQANQTFDVEEGGTLTLECPIENPNGARVIYW 186

Query: 1445 RNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPKI 1624
                  +      +   DG  L II+A+  D+  Y C A NEAG     +T+ +L  P I
Sbjct: 187  YTDAIGKVDPNRSQISGDGTKLFIIQAQESDADRYTCRAHNEAGQDSSVFTVNLLKPPTI 246

Query: 1625 ITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDG-------ENGHTIGADGT 1783
                       S +   L C   G PDP I+W L+G  I  G       +N   +  D
Sbjct: 247  PGEAFSTTEIVSNTTMELNCQPTGKPDPEITWLLDGKPILPGMANVRFEDNNKKLFID-- 304

Query: 1784 LHIEKAEERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCXX 1963
             +I+ ++E    Y C A N  G    +  V+    P++  + ++ +   EG +T I+C
Sbjct: 305  -YIKPSQEGR--YTCRADNQLGRAEQDTYVEISEPPRVVMASDK-MRVVEGRQTTIRCEV 360

Query: 1964 XXXXXXXXX-XKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQKT 2140
                       K+G P   S+ L  S     + +    L D G+Y+C   NKAG A   T
Sbjct: 361  FGEPEPKVSWLKDGEPYT-SDLLQHSTRLSYLHLREATLQDGGKYTCIGTNKAGEARTTT 419

Query: 2141 NLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATTK 2320
             + + VAP I +  R     +G  V + C+ASG P P ITW K+ + L     DE  +
Sbjct: 420  EVEILVAPTIEDEDRVIYGKEGKPVQINCKASGTPYPTITWKKNGKEL-----DEHNSV- 473

Query: 2321 KKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFLS 2500
               +  S+ +    G Y+C A N   S   D  L V   P   PE    +        +
Sbjct: 474  ---LTISNATREDDGKYSCLATNEAGSAVADFLLDVYTRPSFHPETTTFNIIEGHNAKIE 530

Query: 2501 CNATGIPEPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIA 2680
            C   G P+P I+W++       NN      G TL I      D G Y C+A++  G
Sbjct: 531  CKVDGHPKPTITWLKAGRSLNMNNVILSPRGDTLMILKSKRVDAGLYTCVAENTFGANEQ 590

Query: 2681 TRKL-IVNKPSDRPA-----------PIWVECDEKGKPKKTEY-------MIDRGDTPDD 2803
              K+ +  KP    A            I ++C   G P  T Y       +I  G   +
Sbjct: 591  DFKVNVFTKPYIDEAIDQTPKAVAGEKIDLKCPVLGNPTPTVYWKKGDDDIIIDGKHYEL 650

Query: 2804 NPQLLPWKDVEDSSLNGSIAYRCMP-----GPRSSRTVLLHAAPQFIVKPKNTTAAI-GA 2965
               +L  K V +       AY C+        R++  V +   P F  K +N    I
Sbjct: 651  IGDVLRIKTVTEKDTG---AYTCVAINDAGQLRTNYAVDVIGKPTFDRKGENIYEVIEDH 707

Query: 2966 IVELRCSAAGPPHPTITWAK-DGKLIEDSKFEIAYSHLKVTLNST--SDSGEYTCMAQNS 3136
             + + C     P P I W + D  L     + I+    ++T+NS   SD G+YTC A N
Sbjct: 708  DITMDCGVTSRPLPNIAWYRGDNALYIQPHYTISEDGSQITINSARLSDGGKYTCRASNE 767

Query: 3137 VGSSTVSAFINV-------DNNILPTPKP--SSNQKNVAVITCYERNQAYSRGLTWEYNG 3289
             GSS +   + +        +NI+  P    + N      +T   + + Y     W  +G
Sbjct: 768  AGSSDIEVILRILVPPRIDKSNIIGNPLAIVARNIYLECPVTGIPQPEVY-----WTKDG 822

Query: 3290 VPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRR---RHSI------PHLTS 3442
              +    + I +  N     ++   ++  D   YTC   NR     H        P
Sbjct: 823  RDINATDSRIIYAQNNETFGIE--KVQVTDAGRYTCTAVNRGGRIAHDFNLDVLSPPSFD 880

Query: 3443 AFEGVPEVKTIDKVEVNNGDSVVLDCEV-TSDPLTTHVV---WTKNDQKMLD----DDAI 3598
             +   P +K         GD++ L C + T++ +   V+   WTK D   LD    D+
Sbjct: 881  LYRTQPTIK-------REGDTITLTCPIKTAEDVADQVMDVSWTK-DSVALDGVETDNVH 932

Query: 3599 YXXXXXXXXXXXXEKYDEGVYKCVASNSIGKA 3694
                            + G+Y C+A N  G+A
Sbjct: 933  ISDDGRKLTIDKASLVNAGMYTCIALNRAGEA 964



 Score =  144 bits (362), Expect = 3e-32
 Identities = 142/587 (24%), Positives = 243/587 (41%), Gaps = 41/587 (6%)
 Frame = +2

Query: 2087 GEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPA--IT 2260
            G Y+C A NKAG + +   + V V PK+ +  +T  V +G  +TL C     P  A  I
Sbjct: 127  GRYTCIAENKAGRSEKDMIVEVQVPPKMKQANQTFDVEEGGTLTLECPIEN-PNGARVIY 185

Query: 2261 WYKDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPP 2440
            WY D     +    + +    K  I  +   S A  YTC+A N  A  +  +  + ++ P
Sbjct: 186  WYTDAIGKVDPNRSQISGDGTKLFIIQA-QESDADRYTCRAHN-EAGQDSSVFTVNLLKP 243

Query: 2441 EVVPERMNVSTN--PRQTVFLSCNATGIPEPVISWMRDSNIAIQN--NEKYQILGTTLAI 2608
              +P     +T      T+ L+C  TG P+P I+W+ D    +    N +++     L I
Sbjct: 244  PTIPGEAFSTTEIVSNTTMELNCQPTGKPDPEITWLLDGKPILPGMANVRFEDNNKKLFI 303

Query: 2609 RNVLPDDDGFYHCIAKSDAGQKIATRKLIVNKP------SDRPAPI-----WVECDEKGK 2755
              + P  +G Y C A +  G+      + +++P      SD+   +      + C+  G+
Sbjct: 304  DYIKPSQEGRYTCRADNQLGRAEQDTYVEISEPPRVVMASDKMRVVEGRQTTIRCEVFGE 363

Query: 2756 PKKTEYMIDRGD--TPD--DNPQLLPWKDVEDSSLNGSIAYRCMPG-----PRSSRTVLL 2908
            P+     +  G+  T D   +   L +  + +++L     Y C+        R++  V +
Sbjct: 364  PEPKVSWLKDGEPYTSDLLQHSTRLSYLHLREATLQDGGKYTCIGTNKAGEARTTTEVEI 423

Query: 2909 HAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEIAYSHLKVTL 3088
              AP    + +      G  V++ C A+G P+PTITW K+GK +++       S L ++
Sbjct: 424  LVAPTIEDEDRVIYGKEGKPVQINCKASGTPYPTITWKKNGKELDEHN-----SVLTISN 478

Query: 3089 NSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNV-----AVITCYERNQ 3253
             +  D G+Y+C+A N  GS+     ++V     P+  P +   N+     A I C
Sbjct: 479  ATREDDGKYSCLATNEAGSAVADFLLDVYTR--PSFHPETTTFNIIEGHNAKIECKVDGH 536

Query: 3254 AYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNR------- 3412
                 +TW   G  +  N+  +     G  +++  S  K  D  LYTC   N
Sbjct: 537  PKPT-ITWLKAGRSL--NMNNVILSPRGDTLMILKS--KRVDAGLYTCVAENTFGANEQD 591

Query: 3413 ---RRHSIPHLTSAFEGVPEVKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKML 3583
                  + P++  A +  P+    +K++        L C V  +P  T V W K D  ++
Sbjct: 592  FKVNVFTKPYIDEAIDQTPKAVAGEKID--------LKCPVLGNPTPT-VYWKKGDDDII 642

Query: 3584 DDDAIYXXXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNVYG 3724
             D   Y             + D G Y CVA N  G+   +  ++V G
Sbjct: 643  IDGKHYELIGDVLRIKTVTEKDTGAYTCVAINDAGQLRTNYAVDVIG 689



 Score =  103 bits (256), Expect = 5e-20
 Identities = 121/520 (23%), Positives = 203/520 (38%), Gaps = 49/520 (9%)
 Frame = +2

Query: 2309 ATTKKKSVIFSSISPSQA-GVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQ 2485
            A   K  +I   +  S+A G YTC AEN    +E+D+ + V +PP++
Sbjct: 108  AAAVKFPIILKILEGSEAAGRYTCIAENKAGRSEKDMIVEVQVPPKMKQANQTFDVEEGG 167

Query: 2486 TVFLSC---NATGIPEPVISWMRDSNIAIQNNEKYQILG--TTLAIRNVLPDDDGFYHCI 2650
            T+ L C   N  G    VI W  D+   +  N   QI G  T L I      D   Y C
Sbjct: 168  TLTLECPIENPNGAR--VIYWYTDAIGKVDPNRS-QISGDGTKLFIIQAQESDADRYTCR 224

Query: 2651 AKSDAGQKIATRKLIVNKPSDRPAPIW------------VECDEKGKPK-KTEYMIDRGD 2791
            A ++AGQ  +   + + KP   P   +            + C   GKP  +  +++D
Sbjct: 225  AHNEAGQDSSVFTVNLLKPPTIPGEAFSTTEIVSNTTMELNCQPTGKPDPEITWLLDGKP 284

Query: 2792 T---------PDDNPQLLPWKDVEDSSLNGSIAYRCMPGPRSSRT-----VLLHAAPQFI 2929
                       D+N +L  + D    S  G   Y C    +  R      V +   P+ +
Sbjct: 285  ILPGMANVRFEDNNKKL--FIDYIKPSQEGR--YTCRADNQLGRAEQDTYVEISEPPRVV 340

Query: 2930 VKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGK-----LIEDSKFEIAYSHLKVTLNS 3094
            +         G    +RC   G P P ++W KDG+     L++ S   ++Y HL+    +
Sbjct: 341  MASDKMRVVEGRQTTIRCEVFGEPEPKVSWLKDGEPYTSDLLQHST-RLSYLHLREA--T 397

Query: 3095 TSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSN-----QKNVAVITCYERNQAY 3259
              D G+YTC+  N  G +  +  + +   + PT +         +     I C      Y
Sbjct: 398  LQDGGKYTCIGTNKAGEARTTTEVEI--LVAPTIEDEDRVIYGKEGKPVQINCKASGTPY 455

Query: 3260 SRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRHSIP--- 3430
               +TW+ NG  + ++        N  L I + +   +G    Y+C   N    ++
Sbjct: 456  PT-ITWKKNGKELDEH--------NSVLTISNATREDDGK---YSCLATNEAGSAVADFL 503

Query: 3431 ---HLTSAFEGVPEVKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIY 3601
               +   +F   PE  T + +E   G +  ++C+V   P  T + W K  + +  ++ I
Sbjct: 504  LDVYTRPSFH--PETTTFNIIE---GHNAKIECKVDGHPKPT-ITWLKAGRSLNMNNVIL 557

Query: 3602 XXXXXXXXXXXXEKYDEGVYKCVASNSIGKAFDDTQLNVY 3721
                        ++ D G+Y CVA N+ G    D ++NV+
Sbjct: 558  SPRGDTLMILKSKRVDAGLYTCVAENTFGANEQDFKVNVF 597




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