Homology by BLASTX
BLASTX 2.2.4 [Aug-26-2002]
Query= T13H10_1
(4941 letters)
Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
1,967,186 sequences; 661,712,633 total letters
Score E
Sequences producing significant alignments: (bits) Value
gi|17540924|ref|NP_501792.1| a disintegrin-like metalloprotease ... 3403 0.0
gi|39585757|emb|CAE59959.1| Hypothetical protein CBG03449 [Caeno... 3138 0.0
gi|33624896|ref|NP_891550.1| a disintegrin and metalloproteinase... 998 0.0
gi|32130427|sp|Q9P2N4|ATS9_HUMAN ADAMTS-9 precursor (A disintegr... 998 0.0
gi|27463365|gb|AAO15765.1| a disintegrin-like and metalloproteas... 997 0.0
gi|33624902|ref|NP_891551.1| a disintegrin and metalloproteinase... 988 0.0
gi|29611732|sp|P59511|AT20_MOUSE ADAMTS-20 precursor (A disinteg... 985 0.0
gi|31982227|ref|NP_803180.2| a disintegrin-like and metalloprote... 982 0.0
gi|7242979|dbj|BAA92550.1| KIAA1312 protein [Homo sapiens] 982 0.0
gi|50754509|ref|XP_414417.1| PREDICTED: similar to a disintegrin... 929 0.0
gi|29611731|sp|P59510|AT20_HUMAN ADAMTS-20 precursor (A disinteg... 923 0.0
gi|29500537|gb|AAO74896.1| ADAMTS20 A short isoform [Mus musculus] 922 0.0
gi|47219016|emb|CAG02054.1| unnamed protein product [Tetraodon n... 916 0.0
gi|28460690|ref|NP_079279.2| a disintegrin-like and metalloprote... 911 0.0
gi|47224403|emb|CAG08653.1| unnamed protein product [Tetraodon n... 890 0.0
gi|34867907|ref|XP_235610.2| similar to metalloprotease-disinteg... 855 0.0
gi|41281882|ref|NP_787047.1| a disintegrin-like and metalloprote... 845 0.0
gi|34857699|ref|XP_232202.2| similar to a disintegrin-like and m... 837 0.0
gi|33624885|ref|NP_064634.2| a disintegrin and metalloproteinase... 753 0.0
gi|9581879|gb|AAF89106.1| disintegrin metalloproteinase with thr... 751 0.0
gi|48103363|ref|XP_395557.1| similar to a disintegrin and metall... 721 0.0
gi|22328076|gb|AAH36515.1| ADAMTS1 protein [Homo sapiens] 583 e-164
gi|6525075|gb|AAF15317.1| metalloproteinase with thrombospondin ... 583 e-164
gi|23305889|gb|AAN17331.1| metalloproteinase [Equus caballus] 582 e-164
gi|7243073|dbj|BAA92584.1| KIAA1346 protein [Homo sapiens] 582 e-164
gi|5725506|gb|AAD48080.1| METH1 protein [Homo sapiens] 582 e-164
gi|50845384|ref|NP_008919.3| a disintegrin and metalloprotease w... 582 e-164
gi|12644483|sp|Q9UHI8|ATS1_HUMAN ADAMTS-1 precursor (A disintegr... 582 e-164
gi|13242316|ref|NP_077376.1| a disintegrin and metalloproteinase... 580 e-164
gi|11095299|gb|AAG29823.1| ADAMTS-1 [Rattus norvegicus] 576 e-162
gi|1813340|dbj|BAA11088.1| secretory protein containing thrombos... 575 e-162
gi|7513658|pir||T00017 gene ADAMTS-1 protein - mouse >gnl|BL_ORD... 575 e-162
gi|47059082|ref|NP_033751.2| a disintegrin-like and metalloprote... 575 e-162
gi|38089756|ref|XP_134720.4| similar to a disintegrin-like and m... 568 e-160
gi|27719837|ref|XP_235976.1| similar to a disintegrin-like and m... 568 e-160
gi|21265058|ref|NP_620686.1| a disintegrin-like and metalloprote... 567 e-160
gi|47224913|emb|CAG06483.1| unnamed protein product [Tetraodon n... 542 e-152
gi|12643905|sp|Q9UP79|ATS8_HUMAN ADAMTS-8 precursor (A disintegr... 520 e-145
gi|21536392|ref|NP_008968.2| a disintegrin and metalloprotease w... 518 e-145
gi|47222514|emb|CAG02879.1| unnamed protein product [Tetraodon n... 515 e-144
gi|28572997|ref|NP_732036.2| CG14869-PA [Drosophila melanogaster... 515 e-144
gi|45553379|ref|NP_996218.1| CG14869-PB [Drosophila melanogaster... 515 e-144
gi|7304857|ref|NP_038934.1| a disintegrin-like and metalloprotea... 505 e-141
gi|40806187|ref|NP_955387.1| a disintegrin-like and metalloprote... 494 e-137
gi|38649249|gb|AAH63283.1| ADAMTS18 protein [Homo sapiens] 493 e-137
gi|47224912|emb|CAG06482.1| unnamed protein product [Tetraodon n... 489 e-136
gi|50729883|ref|XP_416687.1| PREDICTED: similar to metalloprotei... 486 e-135
gi|7513068|pir||T00355 hypothetical protein KIAA0688 - human 479 e-133
gi|41327756|ref|NP_005090.2| a disintegrin and metalloproteinase... 479 e-133
gi|37182890|gb|AAQ89245.1| ADAMTS4 [Homo sapiens] 479 e-133
gi|15667235|gb|AAL02262.1| aggrecanase 1 [Homo sapiens] 479 e-133
gi|40788330|dbj|BAA31663.2| KIAA0688 protein [Homo sapiens] 479 e-133
gi|31982399|ref|NP_858053.1| a disintegrin-like and metalloprote... 479 e-133
gi|27370274|ref|NP_766433.1| a disintegrin-like and metalloprote... 477 e-132
gi|20381317|gb|AAH27773.1| Adamts4 protein [Mus musculus] 477 e-132
gi|38648772|gb|AAH63293.1| A disintegrin and metalloproteinase w... 476 e-132
gi|27369629|ref|NP_766054.1| a disintegrin-like and metalloprote... 476 e-132
gi|47226859|emb|CAG06701.1| unnamed protein product [Tetraodon n... 473 e-131
gi|17432929|sp|Q9ESP7|ATS4_RAT ADAMTS-4 precursor (A disintegrin... 468 e-130
gi|50761525|ref|XP_424749.1| PREDICTED: similar to a disintegrin... 468 e-130
gi|47217373|emb|CAG00733.1| unnamed protein product [Tetraodon n... 461 e-128
gi|6752976|ref|NP_035912.1| a disintegrin-like and metalloprotea... 461 e-127
gi|21265025|ref|NP_112219.1| a disintegrin-like and metalloprote... 460 e-127
gi|5901888|ref|NP_008969.1| a disintegrin and metalloprotease wi... 460 e-127
gi|32363141|sp|Q8TE57|AT16_HUMAN ADAMTS-16 precursor (A disinteg... 458 e-127
gi|38454260|ref|NP_942056.1| a disintegrin-like and metalloprote... 458 e-127
gi|24899222|dbj|BAC23125.1| KIAA2029 protein [Homo sapiens] 457 e-126
gi|50753855|ref|XP_414158.1| PREDICTED: similar to a disintegrin... 456 e-126
gi|17432918|sp|Q9H324|AT10_HUMAN ADAMTS-10 precursor (A disinteg... 453 e-125
gi|29789429|ref|NP_780710.1| a disintegrin-like and metalloprote... 449 e-124
gi|26339440|dbj|BAC33391.1| unnamed protein product [Mus musculus] 449 e-124
gi|27502095|gb|AAO17380.1| zinc metalloendopeptidase [Mus musculus] 449 e-124
gi|50511261|dbj|BAD32616.1| mKIAA2029 protein [Mus musculus] 447 e-123
gi|13569928|ref|NP_112217.1| a disintegrin-like and metalloprote... 446 e-123
gi|38683827|ref|NP_055087.2| a disintegrin and metalloprotease w... 445 e-123
gi|40806185|ref|NP_620685.2| a disintegrin-like and metalloprote... 444 e-122
gi|34873442|ref|XP_225142.2| similar to ADAMTS-16 precursor (A d... 444 e-122
gi|29336811|sp|Q8TE60|AT18_HUMAN ADAMTS-18 precursor (A disinteg... 443 e-122
gi|38197242|gb|AAH61631.1| A disintegrin and metalloprotease wit... 442 e-122
gi|34854396|ref|XP_226837.2| similar to metalloprotease disinteg... 442 e-122
gi|34864407|ref|XP_235977.2| similar to zinc metalloendopeptidas... 441 e-122
gi|47228458|emb|CAG05278.1| unnamed protein product [Tetraodon n... 441 e-122
gi|50510587|dbj|BAD32279.1| mKIAA0688 protein [Mus musculus] 429 e-118
gi|26336759|dbj|BAC32062.1| unnamed protein product [Mus musculu... 423 e-116
gi|21265061|ref|NP_620687.1| a disintegrin-like and metalloprote... 422 e-116
gi|34865456|ref|XP_236471.2| similar to a disintegrin and metall... 417 e-114
gi|29337034|sp|P59384|AT15_MOUSE ADAMTS-15 (A disintegrin and me... 412 e-113
gi|47226860|emb|CAG06702.1| unnamed protein product [Tetraodon n... 410 e-112
gi|11360273|pir||T47158 hypothetical protein DKFZp762C1110.1 - h... 408 e-112
gi|7656867|ref|NP_055059.1| a disintegrin and metalloprotease wi... 399 e-109
gi|27807141|ref|NP_777056.1| a disintegrin-like and metalloprote... 393 e-107
gi|48112821|ref|XP_396340.1| similar to ENSANGP00000004160 [Apis... 389 e-106
gi|50730027|ref|XP_425541.1| PREDICTED: similar to ADAMTS-5 prec... 389 e-106
gi|50753282|ref|XP_413938.1| PREDICTED: similar to a disintegrin... 386 e-105
gi|38086854|ref|XP_133542.2| similar to a disintegrin-like and m... 382 e-104
gi|21265037|ref|NP_055058.1| a disintegrin-like and metalloprote... 377 e-102
gi|33563307|ref|NP_783574.1| a disintegrin-like and metalloprote... 377 e-102
gi|21265064|ref|NP_620688.1| a disintegrin-like and metalloprote... 375 e-102
gi|21903371|sp|O15072|ATS3_HUMAN ADAMTS-3 precursor (A disintegr... 374 e-101
gi|2224673|dbj|BAA20821.1| KIAA0366 [Homo sapiens] 374 e-101
gi|11131377|sp|Q9UKP4|ATS7_HUMAN ADAMTS-7 precursor (A disintegr... 372 e-101
gi|34870701|ref|XP_213548.2| similar to Adamts2 protein [Rattus ... 371 e-101
gi|28202057|ref|NP_780715.1| a disintegrin-like and metalloprote... 370 e-100
gi|31208263|ref|XP_313098.1| ENSANGP00000012879 [Anopheles gambi... 370 e-100
gi|50746861|ref|XP_426316.1| PREDICTED: similar to a disintegrin... 370 e-100
gi|31243209|ref|XP_322050.1| ENSANGP00000004160 [Anopheles gambi... 370 e-100
gi|25286709|ref|NP_742050.1| a disintegrin-like and metalloprote... 369 e-100
gi|37747541|gb|AAH58991.1| Adamts7 protein [Mus musculus] 367 1e-99
gi|19525737|ref|NP_598377.1| a disintegrin-like and metalloprote... 366 3e-99
gi|47230698|emb|CAF99891.1| unnamed protein product [Tetraodon n... 358 6e-97
gi|17148513|emb|CAD12729.1| ADAMTS-13 protein, variant 2 [Homo s... 357 1e-96
gi|21265046|ref|NP_620596.1| a disintegrin-like and metalloprote... 357 1e-96
gi|16306598|gb|AAL17652.1| von Willebrand factor-cleaving protea... 357 1e-96
gi|21265034|ref|NP_620594.1| a disintegrin-like and metalloprote... 357 1e-96
gi|18874446|gb|AAL79814.1| ADAMTS14 [Homo sapiens] 357 1e-96
gi|21265055|ref|NP_631894.1| a disintegrin-like and metalloprote... 357 1e-96
gi|21265052|ref|NP_542453.2| a disintegrin-like and metalloprote... 357 2e-96
gi|29337086|sp|Q8WXS8|AT14_HUMAN ADAMTS-14 precursor (A disinteg... 356 4e-96
gi|47214646|emb|CAG05166.1| unnamed protein product [Tetraodon n... 355 5e-96
gi|19171188|emb|CAC87943.1| metalloprotease-disintegrin protease... 353 2e-95
gi|10799943|dbj|BAB16473.1| ADAMTS-4 [Rattus norvegicus] 351 1e-94
gi|24639930|ref|NP_572247.1| CG4096-PA [Drosophila melanogaster]... 349 3e-94
gi|38080271|ref|XP_132180.2| similar to a disintegrin-like and m... 348 7e-94
gi|34876765|ref|XP_223279.2| similar to a disintegrin-like and m... 344 1e-92
gi|47604978|ref|NP_001001322.1| a disintegrin-like and metallopr... 342 7e-92
gi|47226613|emb|CAG07772.1| unnamed protein product [Tetraodon n... 340 2e-91
gi|47220863|emb|CAG03070.1| unnamed protein product [Tetraodon n... 338 6e-91
gi|47216064|emb|CAG04803.1| unnamed protein product [Tetraodon n... 338 1e-90
gi|21265043|ref|NP_620595.1| a disintegrin-like and metalloprote... 336 3e-90
gi|48112818|ref|XP_396339.1| similar to a disintegrin-like and m... 332 4e-89
gi|34852641|ref|XP_228290.2| similar to a disintegrin-like and m... 330 3e-88
gi|10799945|dbj|BAB16474.1| ADAMTS-4 [Rattus norvegicus] 328 6e-88
gi|7768707|dbj|BAA95503.1| disintegrin-like and metalloprotease ... 328 6e-88
gi|6049180|gb|AAF02493.1| ADAMTS5 protein [Homo sapiens] 327 2e-87
gi|34853140|ref|XP_342396.1| similar to von Willebrand factor-cl... 321 1e-85
gi|38074586|ref|XP_205053.3| similar to a disintegrin-like and m... 318 6e-85
gi|34880925|ref|XP_341155.1| ADAMTS-4 [Rattus norvegicus] 308 1e-81
gi|26333709|dbj|BAC30572.1| unnamed protein product [Mus musculus] 307 2e-81
gi|38090486|ref|XP_137117.3| similar to ADAMTS-14 precursor (A d... 305 6e-81
gi|50760035|ref|XP_417873.1| PREDICTED: similar to ADAMTS-8 prec... 303 4e-80
gi|39581092|emb|CAE73170.1| Hypothetical protein CBG20566 [Caeno... 298 9e-79
gi|17558476|ref|NP_505017.1| thrombospondin (5I321) [Caenorhabdi... 294 1e-77
gi|25149822|ref|NP_741569.1| thrombospondin (162.1 kD) (5I321) [... 294 1e-77
gi|17558474|ref|NP_505018.1| thrombospondin (169.6 kD) (5I321) [... 294 1e-77
gi|47226569|emb|CAG08585.1| unnamed protein product [Tetraodon n... 292 5e-77
gi|31241999|ref|XP_321430.1| ENSANGP00000022061 [Anopheles gambi... 289 4e-76
gi|47077287|dbj|BAC55159.2| von Willebrand factor-cleaving prote... 287 2e-75
gi|28572038|ref|NP_788751.1| CG33103-PB [Drosophila melanogaster... 286 5e-75
gi|28572036|ref|NP_788752.1| CG33103-PA [Drosophila melanogaster... 286 5e-75
gi|29423262|gb|AAO84907.1| extracellular matrix protein papilin ... 285 6e-75
gi|29423264|gb|AAO84908.1| extracellular matrix protein papilin ... 285 6e-75
gi|11559520|gb|AAG37995.1| extracellular matrix protein papilin ... 285 8e-75
gi|21428946|gb|AAM50192.1| GH22104p [Drosophila melanogaster] 285 8e-75
gi|47221349|emb|CAF97267.1| unnamed protein product [Tetraodon n... 284 2e-74
gi|13346812|gb|AAB99830.2| thrombospondin [Haemonchus contortus] 284 2e-74
gi|48112934|ref|XP_396342.1| similar to a disintegrin-like and m... 283 2e-74
gi|22056190|ref|XP_032181.3| KIAA1233 protein [Homo sapiens] 281 9e-74
gi|46447827|ref|NP_997400.1| a disintegrin-like and metalloprote... 281 1e-73
gi|6164595|gb|AAF04457.1| lacunin [Manduca sexta] 277 2e-72
gi|34935351|ref|XP_234393.2| similar to papilin, proteoglycan-li... 276 4e-72
gi|50749332|ref|XP_421590.1| PREDICTED: similar to ADAMTS-14 pre... 276 5e-72
gi|18700030|ref|NP_570957.1| papilin [Mus musculus] >gnl|BL_ORD_... 275 6e-72
gi|50755104|ref|XP_414611.1| PREDICTED: similar to procollagen I... 274 1e-71
gi|47077154|dbj|BAD18500.1| unnamed protein product [Homo sapiens] 272 5e-71
gi|10435068|dbj|BAB14479.1| unnamed protein product [Homo sapiens] 272 7e-71
gi|38016904|ref|NP_061905.2| thrombospondin repeat containing 1 ... 267 2e-69
gi|38089992|ref|XP_135041.4| a disintegrin-like and metalloprote... 264 2e-68
gi|50752859|ref|XP_413780.1| PREDICTED: similar to RIKEN cDNA B2... 261 9e-68
gi|30089697|ref|NP_659148.2| thrombospondin repeat containing 1;... 260 2e-67
gi|47208620|emb|CAF92891.1| unnamed protein product [Tetraodon n... 259 5e-67
gi|4050089|gb|AAC97963.1| hypothetical protein [Homo sapiens] 258 8e-67
gi|41203743|ref|XP_370765.1| papilin, proteoglycan-like sulfated... 258 8e-67
gi|50748275|ref|XP_426430.1| PREDICTED: similar to papilin [Gall... 258 1e-66
gi|50757225|ref|XP_415435.1| PREDICTED: similar to von Willebran... 257 2e-66
gi|48120927|ref|XP_396472.1| similar to CG33103-PA [Apis mellifera] 250 2e-64
gi|26326687|dbj|BAC27087.1| unnamed protein product [Mus musculus] 249 4e-64
gi|37181342|gb|AAQ88485.1| ADAMTS13 [Homo sapiens] 248 1e-63
gi|13183078|gb|AAK15041.1| a disintegrin-like and metalloproteas... 242 6e-62
gi|50083295|ref|NP_775733.2| papilin [Homo sapiens] 239 4e-61
gi|34861511|ref|XP_227446.2| similar to thrombospondin repeat pr... 236 4e-60
gi|50728216|ref|XP_416037.1| PREDICTED: similar to metalloprotea... 235 9e-60
gi|47221604|emb|CAF97869.1| unnamed protein product [Tetraodon n... 231 1e-58
gi|21327693|ref|NP_640329.1| ADAM-TS related protein 1 isoform 1... 231 2e-58
gi|11225593|gb|AAG33062.1| aggrecanase-2 [Oryctolagus cuniculus] 229 4e-58
gi|21536390|ref|NP_055088.2| a disintegrin and metalloprotease w... 228 9e-58
gi|11131380|sp|Q9UKP5|ATS6_HUMAN ADAMTS-6 precursor (A disintegr... 226 6e-57
gi|48094395|ref|XP_392121.1| similar to thrombospondin repeat co... 218 1e-54
gi|16307156|gb|AAH09667.1| Adamts15 protein [Mus musculus] 216 3e-54
gi|21327691|ref|NP_443098.2| ADAM-TS related protein 1 isoform 2... 212 6e-53
gi|38257660|sp|Q8N6G6|ATL1_HUMAN ADAMTS-like protein 1 precursor... 211 2e-52
gi|37181773|gb|AAQ88693.1| ADAMTSL1 [Homo sapiens] 209 4e-52
gi|34452244|gb|AAP44488.1| egg bindin receptor protein 1 precurs... 206 5e-51
gi|47551295|ref|NP_999830.1| egg bindin receptor 1 [Strongylocen... 205 8e-51
gi|21327695|ref|NP_644669.1| ADAM-TS related protein 1 isoform 3... 204 1e-50
gi|50761759|ref|XP_429157.1| PREDICTED: similar to ADAM-TS relat... 204 2e-50
gi|20987759|gb|AAH30262.1| ADAM-TS related protein 1, isoform 3 ... 202 5e-50
gi|31226481|ref|XP_317715.1| ENSANGP00000002351 [Anopheles gambi... 201 1e-49
gi|37181350|gb|AAQ88489.1| ENWT2803 [Homo sapiens] 199 4e-49
gi|34869455|ref|XP_342859.1| similar to ADAM-TS related protein ... 199 7e-49
gi|19032247|emb|CAD24309.1| putative coagulation serine protease... 192 7e-47
gi|45550179|ref|NP_609406.2| CG6232-PA [Drosophila melanogaster]... 192 9e-47
gi|34862387|ref|XP_343179.1| similar to zinc metalloendopeptidas... 191 1e-46
gi|21430062|gb|AAM50709.1| GM15606p [Drosophila melanogaster] 188 1e-45
gi|34535856|dbj|BAC87455.1| unnamed protein product [Homo sapiens] 187 2e-45
gi|32565116|ref|NP_492405.2| thrombospondin, type I and immunogl... 187 2e-45
gi|39589761|emb|CAE66996.1| Hypothetical protein CBG12394 [Caeno... 187 3e-45
gi|50507766|emb|CAB03121.3| Hypothetical protein F53B6.2a [Caeno... 186 4e-45
gi|6708112|gb|AAF25806.1| zinc metalloendopeptidase [Homo sapiens] 184 2e-44
gi|50753039|ref|XP_413844.1| PREDICTED: similar to a disintegrin... 182 7e-44
gi|27447675|gb|AAO13698.1| disintegrin and metalloproteinase wit... 181 1e-43
gi|39594136|emb|CAE70246.1| Hypothetical protein CBG16735 [Caeno... 181 2e-43
gi|38087703|ref|XP_194370.3| similar to ADAM-TS related protein ... 180 4e-43
gi|7504022|pir||T22545 hypothetical protein F53B6.2 - Caenorhabd... 179 5e-43
gi|48094423|ref|XP_394173.1| similar to CG31619-PA [Apis mellifera] 176 4e-42
gi|48734970|gb|AAH71852.1| TSRC1 protein [Homo sapiens] 176 5e-42
gi|28497344|ref|XP_131451.2| RIKEN cDNA 6720426B09 [Mus musculus... 174 1e-41
gi|27369599|ref|NP_766032.1| RIKEN cDNA B230114P05 [Mus musculus... 173 4e-41
gi|47215615|emb|CAG11646.1| unnamed protein product [Tetraodon n... 172 7e-41
gi|39587995|emb|CAE57226.1| Hypothetical protein CBG00091 [Caeno... 171 1e-40
gi|22268057|gb|AAH27478.1| TSRC1 protein [Homo sapiens] 171 1e-40
gi|32566077|ref|NP_510116.2| ADAMTS family member (162.6 kD) (ad... 171 2e-40
gi|7494529|pir||T18856 angiogenesis inhibitor homolog - Caenorha... 171 2e-40
gi|47216121|emb|CAG11189.1| unnamed protein product [Tetraodon n... 170 3e-40
gi|11131363|sp|Q9TT92|ATS5_BOVIN ADAMTS-5 (A disintegrin and met... 170 3e-40
gi|7513040|pir||T00260 hypothetical protein KIAA0605 - human 169 5e-40
gi|41281450|ref|NP_055509.2| KIAA0605 gene product [Homo sapiens... 169 5e-40
gi|21431483|sp||Q9TT93_2 [Segment 2 of 4] ADAMTS-4 (A disintegri... 169 5e-40
gi|40788301|dbj|BAA25531.2| KIAA0605 protein [Homo sapiens] 169 5e-40
gi|47214463|emb|CAG12468.1| unnamed protein product [Tetraodon n... 167 2e-39
gi|34853361|ref|XP_231125.2| similar to KIAA0605 gene product [R... 167 3e-39
gi|38074590|ref|XP_130065.2| RIKEN cDNA A930008K15 [Mus musculus... 166 5e-39
gi|50751114|ref|XP_422263.1| PREDICTED: similar to KIAA0605 gene... 166 7e-39
gi|13376210|ref|NP_079093.1| hypothetical protein FLJ13710 [Homo... 164 2e-38
gi|24585717|ref|NP_724360.1| CG31619-PB [Drosophila melanogaster... 164 2e-38
gi|24585715|ref|NP_724359.1| CG31619-PA [Drosophila melanogaster... 164 2e-38
gi|17432910|sp|P58459|AT10_MOUSE ADAMTS-10 (A disintegrin and me... 163 4e-38
gi|47212227|emb|CAF93539.1| unnamed protein product [Tetraodon n... 160 4e-37
gi|12697903|dbj|BAB21770.1| KIAA1679 protein [Homo sapiens] 158 1e-36
gi|42656445|ref|XP_046570.6| KIAA1679 protein [Homo sapiens] 158 1e-36
gi|47215023|emb|CAG01847.1| unnamed protein product [Tetraodon n... 157 2e-36
gi|50510541|dbj|BAD32256.1| mKIAA0605 protein [Mus musculus] 157 2e-36
gi|34365426|emb|CAE46049.1| hypothetical protein [Homo sapiens] 155 7e-36
gi|47106073|ref|NP_998769.1| thrombospondin, type I, domain cont... 155 9e-36
gi|14039921|gb|AAK53425.1| aggrecanase-1 [Equus caballus] 155 1e-35
gi|21750893|dbj|BAC03862.1| unnamed protein product [Homo sapiens] 154 3e-35
gi|27370959|gb|AAH40620.1| THSD6 protein [Homo sapiens] 153 4e-35
gi|37552319|ref|XP_294919.2| similar to RIKEN cDNA 2010109H09 [H... 153 4e-35
gi|47077606|dbj|BAD18685.1| unnamed protein product [Homo sapiens] 153 5e-35
gi|40254219|ref|NP_766073.2| RIKEN cDNA D130067I03 [Mus musculus... 152 1e-34
gi|47077285|dbj|BAD18561.1| unnamed protein product [Homo sapiens] 151 2e-34
gi|47227665|emb|CAG09662.1| unnamed protein product [Tetraodon n... 150 4e-34
gi|11038659|ref|NP_067610.1| a disintegrin and metalloprotease w... 150 4e-34
gi|50510877|dbj|BAD32424.1| mKIAA1312 protein [Mus musculus] 150 4e-34
gi|34853752|ref|XP_342185.1| similar to ADAMTS-6 precursor (A di... 149 7e-34
gi|34932009|ref|XP_341620.1| similar to secreted metalloprotease... 149 7e-34
gi|33871984|gb|AAH08840.2| FLJ13710 protein [Homo sapiens] 148 1e-33
gi|34527867|dbj|BAC85503.1| unnamed protein product [Homo sapiens] 147 2e-33
gi|25151927|ref|NP_509286.2| metalloprotease ADAM/reprolysin M12... 146 4e-33
gi|30794619|gb|AAP40541.1| Hypothetical protein F08C6.1c [Caenor... 146 4e-33
gi|30025128|gb|AAA68721.4| Hypothetical protein F08C6.1a [Caenor... 146 4e-33
gi|25900857|dbj|BAC41253.1| ADAMTS-like protease [Caenorhabditis... 146 4e-33
gi|47210114|emb|CAF91841.1| unnamed protein product [Tetraodon n... 146 4e-33
gi|34857642|ref|XP_218841.2| similar to KIAA1233 protein [Rattus... 145 7e-33
gi|38541727|gb|AAH62814.1| Unknown (protein for MGC:73692) [Mus ... 144 2e-32
gi|50753163|ref|XP_413886.1| PREDICTED: similar to a disintegrin... 144 2e-32
gi|20521710|dbj|BAA76804.2| KIAA0960 protein [Homo sapiens] 142 8e-32
gi|14039924|gb|AAK53426.1| aggrecanase-2 [Equus caballus] 142 8e-32
gi|42657849|ref|XP_371877.2| KIAA0960 protein [Homo sapiens] 142 8e-32
gi|42658223|ref|XP_374404.2| similar to KIAA0960 protein [Homo s... 142 8e-32
gi|25152272|ref|NP_509829.2| brain-specific angiogenesis inhibit... 141 2e-31
gi|38083732|ref|XP_357594.1| similar to KIAA0960 protein [Mus mu... 140 2e-31
gi|47209825|emb|CAF91229.1| unnamed protein product [Tetraodon n... 140 4e-31
gi|6714703|emb|CAB66157.1| hypothetical protein [Homo sapiens] 140 4e-31
gi|34857521|ref|XP_218753.2| similar to a disintegrin-like and m... 139 5e-31
gi|34863794|ref|XP_236312.2| similar to thrombospondin repeat pr... 139 7e-31
gi|50510729|dbj|BAD32350.1| mKIAA0960 protein [Mus musculus] 138 1e-30
gi|50732545|ref|XP_418686.1| PREDICTED: similar to KIAA0960 prot... 137 3e-30
gi|12860600|dbj|BAB32000.1| unnamed protein product [Mus musculus] 135 1e-29
gi|47077263|dbj|BAD18550.1| unnamed protein product [Homo sapiens] 135 1e-29
gi|47196348|emb|CAF88701.1| unnamed protein product [Tetraodon n... 134 2e-29
gi|7768709|dbj|BAA95504.1| disintegrin-like and metalloprotease ... 134 2e-29
gi|39597810|emb|CAE68502.1| Hypothetical protein CBG14312 [Caeno... 132 6e-29
gi|28395497|gb|AAO39046.1| TSP1 domain-containing protein TSP2 p... 132 8e-29
gi|46227085|gb|EAK88035.1| cryptosporidium TRAP-C2 extracellular... 132 8e-29
gi|8977890|emb|CAB95770.1| ADAMTS7, alternatively spliced produc... 132 1e-28
gi|7512603|pir||T14764 hypothetical protein DKFZp434H204.1 - hum... 132 1e-28
gi|26330920|dbj|BAC29190.1| unnamed protein product [Mus musculus] 131 2e-28
gi|34879724|ref|XP_222597.2| similar to KIAA1679 protein [Rattus... 131 2e-28
gi|32565118|ref|NP_871884.1| immunoglobulin-like and thrombospon... 129 9e-28
gi|13385092|ref|NP_079905.1| thrombospondin, type I domain conta... 127 2e-27
gi|25151372|ref|NP_508681.2| metalloprotease ADAM/reprolysin M12... 127 3e-27
gi|7507985|pir||T16892 hypothetical protein T19D2.1 - Caenorhabd... 127 3e-27
gi|7508112|pir||T25061 hypothetical protein T21B6.3 - Caenorhabd... 126 6e-27
gi|22028288|gb|AAH34843.1| Thsd6 protein [Mus musculus] 125 8e-27
gi|13625178|gb|AAK34948.1| thrombospondin [Homo sapiens] 125 1e-26
gi|47218763|emb|CAG02749.1| unnamed protein product [Tetraodon n... 124 2e-26
gi|17550860|ref|NP_509194.1| hemicentin (XH708) [Caenorhabditis ... 124 3e-26
gi|17550862|ref|NP_509195.1| hemicentin (XH708) [Caenorhabditis ... 124 3e-26
gi|34862306|ref|XP_234919.2| similar to RIKEN cDNA 2010109H09 [R... 123 4e-26
gi|48139395|ref|XP_393459.1| similar to CG6232-PA [Apis mellifera] 123 4e-26
gi|39594923|emb|CAE70791.1| Hypothetical protein CBG17547 [Caeno... 122 9e-26
gi|33341752|gb|AAQ15247.1| PP12585 [Homo sapiens] 120 3e-25
gi|50808949|ref|XP_424621.1| PREDICTED: similar to KIAA0605 gene... 119 7e-25
gi|6330729|dbj|BAA86547.1| KIAA1233 protein [Homo sapiens] 119 7e-25
gi|39586796|emb|CAE65839.1| Hypothetical protein CBG10970 [Caeno... 119 1e-24
gi|20130265|ref|NP_611718.1| CG3622-PB [Drosophila melanogaster]... 118 1e-24
gi|16041076|dbj|BAB69705.1| hypothetical protein [Macaca fascicu... 117 4e-24
gi|27369758|ref|NP_766130.1| hypothetical protein 5930437A14 [Mu... 115 8e-24
gi|47224404|emb|CAG08654.1| unnamed protein product [Tetraodon n... 115 8e-24
gi|34869457|ref|XP_233135.2| similar to hypothetical protein 593... 115 8e-24
gi|24658605|ref|NP_726248.1| CG3622-PA [Drosophila melanogaster]... 115 1e-23
gi|19527927|gb|AAL90078.1| AT15733p [Drosophila melanogaster] 115 1e-23
gi|7498609|pir||T15976 hypothetical protein F08C6.1 - Caenorhabd... 114 2e-23
gi|31212147|ref|XP_315058.1| ENSANGP00000002429 [Anopheles gambi... 113 4e-23
gi|47212190|emb|CAF95223.1| unnamed protein product [Tetraodon n... 113 5e-23
gi|17939568|gb|AAH19344.1| KIAA1679 protein [Homo sapiens] >gnl|... 111 2e-22
gi|10764200|gb|AAG22601.1| aggrecanase-2 [Oryctolagus cuniculus] 110 3e-22
gi|50757215|ref|XP_415430.1| PREDICTED: similar to KIAA0605 prot... 110 3e-22
gi|28195400|ref|NP_777131.1| SCO-spondin [Bos taurus] >gnl|BL_OR... 110 3e-22
gi|18859415|ref|NP_571592.1| spondin 1b [Danio rerio] >gnl|BL_OR... 110 4e-22
gi|45124835|emb|CAF33425.1| SCO-spondin [Rattus norvegicus] 109 6e-22
gi|34526569|dbj|BAC85245.1| unnamed protein product [Homo sapiens] 109 6e-22
gi|34880529|ref|XP_222716.2| similar to hemicentin; fibulin 6 [R... 109 8e-22
gi|13872813|emb|CAC37630.1| fibulin-6 [Homo sapiens] 109 8e-22
gi|31083306|ref|NP_114141.1| hemicentin; fibulin 6 [Homo sapiens] 109 8e-22
gi|14575679|gb|AAK68690.1| hemicentin [Homo sapiens] 109 8e-22
gi|26342140|dbj|BAC34732.1| unnamed protein product [Mus musculus] 108 1e-21
gi|26349275|dbj|BAC38277.1| unnamed protein product [Mus musculus] 108 1e-21
gi|47210354|emb|CAF90233.1| unnamed protein product [Tetraodon n... 107 2e-21
gi|31234913|ref|XP_319147.1| ENSANGP00000011930 [Anopheles gambi... 107 3e-21
gi|38073489|ref|XP_136261.3| similar to hemicentin; fibulin 6 [M... 105 1e-20
gi|34857453|ref|XP_218840.2| similar to a disintegrin-like and m... 105 1e-20
gi|50753037|ref|XP_413843.1| PREDICTED: similar to a disintegrin... 104 2e-20
gi|47213526|emb|CAF96679.1| unnamed protein product [Tetraodon n... 104 2e-20
gi|47219495|emb|CAG10859.1| unnamed protein product [Tetraodon n... 103 5e-20
gi|50753161|ref|XP_413885.1| PREDICTED: similar to a disintegrin... 102 7e-20
gi|30424661|ref|NP_775604.1| subcommissural organ spondin; SCO-s... 102 7e-20
gi|26347403|dbj|BAC37350.1| unnamed protein product [Mus musculus] 102 7e-20
gi|39930367|ref|NP_061860.1| semaphorin 5B [Homo sapiens] >gnl|B... 102 7e-20
gi|6166501|gb|AAF04860.1| semaphorin 5C [Drosophila melanogaster] 102 1e-19
gi|10764198|gb|AAG22600.1| aggrecanase-1 [Oryctolagus cuniculus] 101 2e-19
gi|48098411|ref|XP_394067.1| similar to ENSANGP00000001179 [Apis... 101 2e-19
gi|33589336|gb|AAQ22435.1| RE68041p [Drosophila melanogaster] 100 5e-19
gi|45550455|ref|NP_611293.3| CG5661-PA [Drosophila melanogaster]... 100 5e-19
gi|21265049|ref|NP_620597.1| a disintegrin-like and metalloprote... 99 8e-19
gi|19032241|emb|CAD24306.1| putative coagulation serine protease... 99 1e-18
gi|37577168|ref|NP_922932.1| similar to ADAMTS-10 precursor [Hom... 99 1e-18
gi|7305473|ref|NP_038689.1| semaphorin 5B [Mus musculus] >gnl|BL... 99 1e-18
gi|37360388|dbj|BAC98172.1| mKIAA1445 protein [Mus musculus] 99 1e-18
gi|32965153|gb|AAP91764.1| HrTT-1-like [Ciona intestinalis] 98 2e-18
gi|7959149|dbj|BAA95969.1| KIAA1445 protein [Homo sapiens] 98 2e-18
gi|50418190|gb|AAH77726.1| SEMA5B protein [Homo sapiens] 98 2e-18
gi|13543229|gb|AAH05780.1| Adamts8 protein [Mus musculus] 98 2e-18
gi|48474986|sp|Q9P283|SM5B_HUMAN Semaphorin 5B precursor 98 2e-18
gi|50729885|ref|XP_416688.1| PREDICTED: similar to secretory pro... 97 3e-18
gi|45382337|ref|NP_990182.1| F-spondin [Gallus gallus] >gnl|BL_O... 97 5e-18
gi|26334529|dbj|BAC30965.1| unnamed protein product [Mus musculus] 97 5e-18
gi|5326919|emb|CAB46239.1| SCO-spondin [Bos taurus] 96 9e-18
gi|16741222|gb|AAH16451.1| Unknown (protein for IMAGE:3451933) [... 95 1e-17
gi|18859413|ref|NP_571590.1| spondin 1a [Danio rerio] >gnl|BL_OR... 95 1e-17
gi|47218741|emb|CAG05713.1| unnamed protein product [Tetraodon n... 95 1e-17
gi|6677915|ref|NP_033180.1| semaphorin 5A; semaphorin F; M-Sema ... 95 1e-17
gi|16740679|gb|AAH16215.1| Tsrc1 protein [Mus musculus] 94 3e-17
gi|10441879|gb|AAG17217.1| unknown [Homo sapiens] 94 4e-17
gi|47222186|emb|CAG11612.1| unnamed protein product [Tetraodon n... 93 6e-17
gi|50777084|ref|XP_427336.1| PREDICTED: similar to a disintegrin... 92 1e-16
gi|544354|sp|P35447|FSPO_XENLA F-spondin precursor >gnl|BL_ORD_I... 91 2e-16
gi|50750686|ref|XP_422096.1| PREDICTED: similar to MGC68835 prot... 91 2e-16
gi|4502355|ref|NP_001693.1| brain-specific angiogenesis inhibito... 91 3e-16
gi|47229448|emb|CAF99436.1| unnamed protein product [Tetraodon n... 91 4e-16
gi|30851457|gb|AAH52397.1| Sema5b protein [Mus musculus] 91 4e-16
gi|1923217|gb|AAB63303.1| micronemal protein MIC2 [Toxoplasma go... 90 5e-16
gi|27807443|ref|NP_777168.1| spondin 1, (f-spondin) extracellula... 90 5e-16
gi|50731916|ref|XP_418415.1| PREDICTED: similar to Brain-specifi... 90 5e-16
gi|47208689|emb|CAF90479.1| unnamed protein product [Tetraodon n... 89 8e-16
gi|25453372|ref|NP_742064.1| f-spondin [Rattus norvegicus] >gnl|... 89 1e-15
gi|50794584|ref|XP_423706.1| PREDICTED: similar to VWF-cleaving ... 89 1e-15
gi|20987843|gb|AAH30339.1| Spon1 protein [Mus musculus] 89 1e-15
gi|21704174|ref|NP_663559.1| spondin 1, (f-spondin) extracellula... 89 1e-15
gi|11320820|dbj|BAB18461.1| VSGP/F-spondin [Homo sapiens] 89 1e-15
gi|31235266|ref|XP_319207.1| ENSANGP00000018693 [Anopheles gambi... 89 1e-15
gi|38073307|ref|XP_355230.1| similar to KIAA1679 protein [Mus mu... 88 2e-15
gi|4506881|ref|NP_003957.1| semaphorin 5A; semaphorin F; sema do... 87 3e-15
gi|21410063|gb|AAH30812.1| ADAMTS4 protein [Homo sapiens] 87 3e-15
gi|20521646|dbj|BAA34482.2| KIAA0762 protein [Homo sapiens] 87 4e-15
gi|38089870|ref|XP_356162.1| similar to hypothetical protein [Mu... 87 4e-15
gi|38084511|ref|XP_355112.1| similar to secreted metalloprotease... 87 5e-15
gi|7498832|pir||T34212 hypothetical protein F10E7.4 - Caenorhabd... 87 5e-15
gi|32564253|ref|NP_495473.2| reeler region and thrombospondin, t... 87 5e-15
gi|41055343|ref|NP_956931.1| hypothetical protein MGC64059 [Dani... 86 9e-15
gi|24307905|ref|NP_006099.1| spondin 1, extracellular matrix pro... 86 1e-14
gi|50762274|ref|XP_425000.1| PREDICTED: similar to a disintegrin... 86 1e-14
gi|27469558|gb|AAH42057.1| PAPLN protein [Homo sapiens] 85 2e-14
gi|34866798|ref|XP_343261.1| similar to Brain-specific angiogene... 85 2e-14
gi|39582297|emb|CAE67546.1| Hypothetical protein CBG13071 [Caeno... 84 3e-14
gi|38083689|ref|XP_287555.2| similar to KIAA0960 protein [Mus mu... 84 3e-14
gi|6017001|gb|AAF01565.1| thrombospondin-related adhesive protei... 83 6e-14
gi|37590696|gb|AAH59288.1| MGC68835 protein [Xenopus laevis] 83 6e-14
gi|47223515|emb|CAF98002.1| unnamed protein product [Tetraodon n... 83 6e-14
gi|28866952|ref|NP_783573.2| brain-specific angiogenesis inhibit... 82 1e-13
gi|37359988|dbj|BAC97972.1| mKIAA0550 protein [Mus musculus] 82 1e-13
gi|23480151|gb|EAA16792.1| ookinete protein-related [Plasmodium ... 82 1e-13
gi|1147634|gb|AAC48313.1| micronemal TRAP-C1 protein homolog [Cr... 82 2e-13
gi|41386685|ref|NP_776621.1| thrombospondin; thrombospondin 1 [B... 81 2e-13
gi|21430808|gb|AAM51082.1| SD16815p [Drosophila melanogaster] 81 2e-13
gi|31207109|ref|XP_312521.1| ENSANGP00000001179 [Anopheles gambi... 81 2e-13
gi|2388718|gb|AAC48311.1| thrombospondin related adhesive protei... 81 3e-13
gi|4502359|ref|NP_001695.1| brain-specific angiogenesis inhibito... 80 4e-13
gi|50748348|ref|XP_421205.1| PREDICTED: similar to thrombospondi... 80 4e-13
gi|20521081|dbj|BAA25476.2| KIAA0550 protein [Homo sapiens] 80 4e-13
gi|7513013|pir||T00326 hypothetical protein KIAA0550 - human 80 4e-13
gi|549135|sp|P35448|TSP1_XENLA Thrombospondin 1 precursor 80 5e-13
gi|50796678|ref|XP_423882.1| PREDICTED: similar to procollagen I... 80 5e-13
gi|18389874|gb|AAL68774.1| aggrecanase-1 [Mus musculus] 80 5e-13
gi|33340123|gb|AAQ14549.1| thrombospondin 1 [Rattus norvegicus] 80 6e-13
gi|31240663|ref|XP_320745.1| ENSANGP00000008856 [Anopheles gambi... 80 6e-13
gi|50750784|ref|XP_422142.1| PREDICTED: similar to RIKEN cDNA D1... 80 6e-13
gi|27502731|gb|AAH42422.1| Thrombospondin 1 [Mus musculus] 79 8e-13
gi|47059073|ref|NP_035710.2| thrombospondin 1 [Mus musculus] >gn... 79 8e-13
gi|34874588|ref|XP_237019.2| similar to brain-specific angiogene... 79 8e-13
gi|549134|sp|P35441|TSP1_MOUSE Thrombospondin 1 precursor >gnl|B... 79 8e-13
gi|567240|gb|AAA53063.1| thrombospondin 1 79 8e-13
gi|39597869|emb|CAE68561.1| Hypothetical protein CBG14396 [Caeno... 79 8e-13
gi|34871673|ref|XP_232778.2| similar to brain-specific angiogene... 79 1e-12
gi|27414503|ref|NP_775094.1| brain-specific angiogenesis inhibit... 79 1e-12
gi|34784563|gb|AAH56926.1| Bai2 protein [Mus musculus] 79 1e-12
gi|37465|emb|CAA32889.1| precursor polypeptide (AA -31 to 1139) ... 79 1e-12
gi|135717|sp|P07996|TSP1_HUMAN Thrombospondin 1 precursor >gnl|B... 79 1e-12
gi|40317626|ref|NP_003237.2| thrombospondin 1 precursor [Homo sa... 79 1e-12
gi|50794615|ref|XP_428024.1| PREDICTED: similar to SCO-spondin, ... 79 1e-12
gi|323091|pir||A45638 immunodominant microneme protein Etp100 - ... 79 1e-12
gi|27923927|ref|NP_778156.1| brain-specific angiogenesis inhibit... 78 2e-12
gi|50415019|gb|AAH77925.1| Unknown (protein for MGC:80861) [Xeno... 78 2e-12
gi|21928571|dbj|BAC05874.1| seven transmembrane helix receptor [... 78 2e-12
gi|4502357|ref|NP_001694.1| brain-specific angiogenesis inhibito... 78 2e-12
gi|34933169|ref|XP_216784.2| similar to properdin (AA 5 - 441) [... 77 3e-12
gi|38173792|gb|AAH60804.1| A disintegrin and metalloprotease dom... 77 3e-12
gi|37182874|gb|AAQ89237.1| ADAM-12 [Homo sapiens] 77 3e-12
gi|13259518|ref|NP_003465.2| a disintegrin and metalloprotease d... 77 3e-12
gi|11497000|ref|NP_067673.1| a disintegrin and metalloprotease d... 77 3e-12
gi|13027662|gb|AAC08703.2| meltrin-S [Homo sapiens] 77 3e-12
gi|48976107|ref|NP_001001755.1| thrombospondin 2 [Gallus gallus]... 77 4e-12
gi|38086042|ref|XP_135820.3| properdin factor, complement [Mus m... 77 4e-12
gi|31197929|ref|XP_307912.1| ENSANGP00000021854 [Anopheles gambi... 77 4e-12
gi|50741479|ref|XP_419599.1| PREDICTED: similar to thrombospondi... 77 4e-12
gi|14041957|dbj|BAB55049.1| unnamed protein product [Homo sapiens] 77 4e-12
gi|26335661|dbj|BAC31531.1| unnamed protein product [Mus musculus] 77 5e-12
gi|26345842|dbj|BAC36572.1| unnamed protein product [Mus musculus] 77 5e-12
gi|34879072|ref|XP_224964.2| similar to metalloprotease/disinteg... 76 7e-12
gi|47188710|emb|CAF94286.1| unnamed protein product [Tetraodon n... 76 7e-12
gi|21703188|gb|AAM76091.1| thrombospondin-like protein [Boltenia... 76 7e-12
gi|542663|pir||S41607 atrolysin A (EC 3.4.24.1) - western diamon... 76 9e-12
gi|5139521|emb|CAB45562.1| CTRP protein [Plasmodium berghei] >gn... 76 9e-12
gi|21359696|gb|AAM49575.1| disintegrin/metalloproteinase domain ... 76 9e-12
gi|47230253|emb|CAG10667.1| unnamed protein product [Tetraodon n... 76 9e-12
gi|4501915|ref|NP_003807.1| a disintegrin and metalloproteinase ... 76 9e-12
gi|6680640|ref|NP_031426.1| a disintegrin and metalloprotease do... 76 9e-12
gi|47222313|emb|CAG05062.1| unnamed protein product [Tetraodon n... 75 1e-11
gi|18043812|gb|AAH19825.1| SPON1 protein [Homo sapiens] 75 1e-11
gi|3328304|gb|AAC26812.1| thrombospondin-related adhesive protei... 75 1e-11
gi|27573793|pdb|1LSL|A Chain A, Crystal Structure Of The Thrombo... 75 2e-11
gi|50773423|ref|XP_427191.1| PREDICTED: similar to THSD6 protein... 75 2e-11
gi|40317628|ref|NP_003238.2| thrombospondin 2 precursor [Homo sa... 75 2e-11
gi|28972033|dbj|BAC65470.1| mKIAA0021 protein [Mus musculus] 75 2e-11
gi|6680644|ref|NP_031430.1| a disintegrin and metalloprotease do... 75 2e-11
gi|50732087|ref|XP_418472.1| PREDICTED: similar to SCO-spondin [... 75 2e-11
gi|201995|gb|AAA40432.1| thrombospondin 74 3e-11
gi|6755779|ref|NP_035711.1| thrombospondin 2 [Mus musculus] >gnl... 74 3e-11
gi|27464928|gb|AAO16244.1| Thbs2 [Mus musculus] 74 3e-11
gi|31565630|gb|AAH53702.1| Thrombospondin 2 [Mus musculus] 74 3e-11
gi|34854062|ref|XP_214778.2| similar to Thbs2 [Rattus norvegicus] 74 3e-11
gi|549136|sp|P35442|TSP2_HUMAN Thrombospondin 2 precursor >gnl|B... 74 3e-11
gi|47224540|emb|CAG03524.1| unnamed protein product [Tetraodon n... 74 3e-11
gi|6093793|sp|Q64181|PROP_CAVPO Properdin precursor (Factor P) >... 74 4e-11
gi|34869369|ref|XP_239438.2| similar to sema domain, seven throm... 74 4e-11
gi|48094906|ref|XP_394300.1| similar to CG6953-PA [Apis mellifera] 74 4e-11
gi|47225217|emb|CAF98844.1| unnamed protein product [Tetraodon n... 74 4e-11
gi|28875793|ref|NP_789861.1| thrombospondin 2 [Bos taurus] >gnl|... 74 5e-11
gi|130987|sp|P11680|PROP_MOUSE Properdin (Factor P) >gnl|BL_ORD_... 74 5e-11
gi|4106003|gb|AAD02653.1| metalloprotease [Gloydius halys] 73 6e-11
gi|13516887|dbj|BAB40595.1| Ci-META2 [Ciona intestinalis] 73 6e-11
gi|9858697|gb|AAG01093.1| thrombospondin-related adhesive protei... 73 6e-11
gi|47198408|emb|CAF87976.1| unnamed protein product [Tetraodon n... 73 6e-11
gi|47216814|emb|CAG10136.1| unnamed protein product [Tetraodon n... 73 6e-11
gi|31322303|gb|AAP20640.1| metalloproteinase/disintegrin ussurin... 73 8e-11
gi|34861174|ref|XP_219470.2| similar to tubulin, gamma complex a... 73 8e-11
gi|31322305|gb|AAP20641.1| metalloproteinase precursor [Gloydius... 73 8e-11
gi|872033|emb|CAA60952.1| thrombospondin [Bos taurus] 73 8e-11
gi|320927|pir||A45517 coccidiosis-related antigen - Eimeria tene... 73 8e-11
gi|50747468|ref|XP_420886.1| PREDICTED: similar to ADAM 13 [Gall... 72 1e-10
gi|9858699|gb|AAG01094.1| thrombospondin-related adhesive protei... 72 1e-10
gi|509281|emb|CAA54690.1| TRAP-C1 (thrombospondin related adhesi... 72 1e-10
gi|50759812|ref|XP_417793.1| PREDICTED: similar to Brain-specifi... 72 1e-10
gi|9858701|gb|AAG01095.1| thrombospondin-related adhesive protei... 72 1e-10
gi|18030088|gb|AAL56617.1| ADAM 12 [Coturnix coturnix] 72 2e-10
gi|34935328|ref|XP_234368.2| similar to metalloprotease-disinteg... 72 2e-10
gi|16768638|gb|AAL28538.1| HL01082p [Drosophila melanogaster] 71 2e-10
gi|17137680|ref|NP_477435.1| CG6953-PA [Drosophila melanogaster]... 71 2e-10
gi|14794943|gb|AAK73517.1| metalloproteinase [Gloydius halys bre... 71 2e-10
gi|45551111|ref|NP_725647.2| CG6953-PB [Drosophila melanogaster]... 71 2e-10
>gi|17540924|ref|NP_501792.1| a disintegrin-like metalloprotease with
thrombospondin type 1 motifs 9B, abnormal GONad
development GON-1 (gon-1) [Caenorhabditis elegans]
gi|7499847|pir||T21371 hypothetical protein F25H8.3 - Caenorhabditis
elegans
gi|3876367|emb|CAA93287.1| Hypothetical protein F25H8.3
[Caenorhabditis elegans]
gi|3879882|emb|CAA93288.1| Hypothetical protein F25H8.3
[Caenorhabditis elegans]
Length = 2165
Score = 3403 bits (8823), Expect = 0.0
Identities = 1582/1647 (96%), Positives = 1582/1647 (96%)
Frame = -1
Query: 4941 MRSIGGSFHXXXXXXXXXXXXXXXXXXXLQSGSGTISEFSSDVLFSRAKYSGVPVHHSRW 4762
MRSIGGSFH LQSGSGTISEFSSDVLFSRAKYSGVPVHHSRW
Sbjct: 1 MRSIGGSFHLLQPVVAALILLVVCLVYALQSGSGTISEFSSDVLFSRAKYSGVPVHHSRW 60
Query: 4761 RQDAGIHVIDSHHIVRRDSYGRRGKRDVTSTDRRRRLQGVARDCGHACHLRLRSDDAVYI 4582
RQDAGIHVIDSHHIVRRDSYGRRGKRDVTSTDRRRRLQGVARDCGHACHLRLRSDDAVYI
Sbjct: 61 RQDAGIHVIDSHHIVRRDSYGRRGKRDVTSTDRRRRLQGVARDCGHACHLRLRSDDAVYI 120
Query: 4581 VHLHRWNQIPDSHNKSVPHFSNSNFAPMVLYLDSEEEVRGGMSRTDPDCIYRAHVKGVHQ 4402
VHLHRWNQIPDSHNKSVPHFSNSNFAPMVLYLDSEEEVRGGMSRTDPDCIYRAHVKGVHQ
Sbjct: 121 VHLHRWNQIPDSHNKSVPHFSNSNFAPMVLYLDSEEEVRGGMSRTDPDCIYRAHVKGVHQ 180
Query: 4401 HSIVNLCDSEDGLYGMLALPSGIHTVEPIISGNGTEHDGASRHRQHLVRKFDPMHFKSFD 4222
HSIVNLCDSEDGLYGMLALPSGIHTVEPIISGNGTEHDGASRHRQHLVRKFDPMHFKSFD
Sbjct: 181 HSIVNLCDSEDGLYGMLALPSGIHTVEPIISGNGTEHDGASRHRQHLVRKFDPMHFKSFD 240
Query: 4221 HLNSTSVNETETTVATWQDQWEDVIERKARSRRAANSWDHYVEVLVVADTKMYEYHGRSL 4042
HLNSTSVNETETTVATWQDQWEDVIERKARSRRAANSWDHYVEVLVVADTKMYEYHGRSL
Sbjct: 241 HLNSTSVNETETTVATWQDQWEDVIERKARSRRAANSWDHYVEVLVVADTKMYEYHGRSL 300
Query: 4041 EDYVLTLFSTVASIYRHQSLRASXXXXXXXXXXXKTENAGPRITQNAQQTLQDFCRWQQY 3862
EDYVLTLFSTVASIYRHQSLRAS KTENAGPRITQNAQQTLQDFCRWQQY
Sbjct: 301 EDYVLTLFSTVASIYRHQSLRASINVVVVKLIVLKTENAGPRITQNAQQTLQDFCRWQQY 360
Query: 3861 YNDPDDSSVQHHDVAILLTRKDICRSQGKCDTLGLAELGTMCDMQKSCAIIEDNGLSAAF 3682
YNDPDDSSVQHHDVAILLTRKDICRSQGKCDTLGLAELGTMCDMQKSCAIIEDNGLSAAF
Sbjct: 361 YNDPDDSSVQHHDVAILLTRKDICRSQGKCDTLGLAELGTMCDMQKSCAIIEDNGLSAAF 420
Query: 3681 TIAHELGHVFSIPHDDERKCSTYMPVNKVCKFQSTKFDKTQFQNNFHIMAPTLEYNTHPW 3502
TIAHELGHVFSIPHDDERKCSTYMPVNKVCKFQSTKFDKTQFQNNFHIMAPTLEYNTHPW
Sbjct: 421 TIAHELGHVFSIPHDDERKCSTYMPVNKVCKFQSTKFDKTQFQNNFHIMAPTLEYNTHPW 480
Query: 3501 SWSPCSAGMLERFLENNRGQTQCLFDQPVERRYYEDVFVRDEPGKKYDAHQQCKFVFGPA 3322
SWSPCSAGMLERFLENNRGQTQCLFDQPVERRYYEDVFVRDEPGKKYDAHQQCKFVFGPA
Sbjct: 481 SWSPCSAGMLERFLENNRGQTQCLFDQPVERRYYEDVFVRDEPGKKYDAHQQCKFVFGPA 540
Query: 3321 SELCPYMPTCRRLWCATFYGSQMGCRTQHMPWADGTPCDESRSMFCHHGACVRLAPESLT 3142
SELCPYMPTCRRLWCATFYGSQMGCRTQHMPWADGTPCDESRSMFCHHGACVRLAPESLT
Sbjct: 541 SELCPYMPTCRRLWCATFYGSQMGCRTQHMPWADGTPCDESRSMFCHHGACVRLAPESLT 600
Query: 3141 KIDGQWGDWRSWGECSRTCGGGVQKGLRDCDSPKPRNGGKYCVGQRERYRSCNTQECPWD 2962
KIDGQWGDWRSWGECSRTCGGGVQKGLRDCDSPKPRNGGKYCVGQRERYRSCNTQECPWD
Sbjct: 601 KIDGQWGDWRSWGECSRTCGGGVQKGLRDCDSPKPRNGGKYCVGQRERYRSCNTQECPWD 660
Query: 2961 TQPYREVQCSEFNNKDIGIQGVASTNTHWVPKYANVAPNERCKLYCRLSGSAAFYLLRDK 2782
TQPYREVQCSEFNNKDIGIQGVASTNTHWVPKYANVAPNERCKLYCRLSGSAAFYLLRDK
Sbjct: 661 TQPYREVQCSEFNNKDIGIQGVASTNTHWVPKYANVAPNERCKLYCRLSGSAAFYLLRDK 720
Query: 2781 VVDGTPCDRNGDDICVAGACMPAGCDHQLHSTLRRDKCGVCGGDDSSCKVVKGTFNEQGT 2602
VVDGTPCDRNGDDICVAGACMPAGCDHQLHSTLRRDKCGVCGGDDSSCKVVKGTFNEQGT
Sbjct: 721 VVDGTPCDRNGDDICVAGACMPAGCDHQLHSTLRRDKCGVCGGDDSSCKVVKGTFNEQGT 780
Query: 2601 FGYNEVMKIPAGSANIDIRQKGYNNMKEDDNYLSLRAANGEFLLNGHFQVSLARQQIAFQ 2422
FGYNEVMKIPAGSANIDIRQKGYNNMKEDDNYLSLRAANGEFLLNGHFQVSLARQQIAFQ
Sbjct: 781 FGYNEVMKIPAGSANIDIRQKGYNNMKEDDNYLSLRAANGEFLLNGHFQVSLARQQIAFQ 840
Query: 2421 DTVLEYSGSDAIIERINGTGPIRSDIYVHVLSVGSHPPDISYEYMTAAVPNAVIRPISSA 2242
DTVLEYSGSDAIIERINGTGPIRSDIYVHVLSVGSHPPDISYEYMTAAVPNAVIRPISSA
Sbjct: 841 DTVLEYSGSDAIIERINGTGPIRSDIYVHVLSVGSHPPDISYEYMTAAVPNAVIRPISSA 900
Query: 2241 LYLWRVTDTWTECDRACRGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCST 2062
LYLWRVTDTWTECDRACRGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCST
Sbjct: 901 LYLWRVTDTWTECDRACRGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCST 960
Query: 2061 RWITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYIDCSGR 1882
RWITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYIDCSGR
Sbjct: 961 RWITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYIDCSGR 1020
Query: 1881 KWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWV 1702
KWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWV
Sbjct: 1021 KWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWV 1080
Query: 1701 YGHWSECSRSCDGGVKMRHAQCLDAADRETHTSRCGPAQTQEHCNEHACTWWQFGVWSDC 1522
YGHWSECSRSCDGGVKMRHAQCLDAADRETHTSRCGPAQTQEHCNEHACTWWQFGVWSDC
Sbjct: 1081 YGHWSECSRSCDGGVKMRHAQCLDAADRETHTSRCGPAQTQEHCNEHACTWWQFGVWSDC 1140
Query: 1521 SAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIITKPCHRESCPKYKLGEWSQCSVSCE 1342
SAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIITKPCHRESCPKYKLGEWSQCSVSCE
Sbjct: 1141 SAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIITKPCHRESCPKYKLGEWSQCSVSCE 1200
Query: 1341 DGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNTDWSACSVSCGIGH 1162
DGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNTDWSACSVSCGIGH
Sbjct: 1201 DGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNTDWSACSVSCGIGH 1260
Query: 1161 RERTTECIYREQSVDASFCGDTKMPETSQTCHLLPCTSWKPSHWSPCSVTCGSGIQTRSV 982
RERTTECIYREQSVDASFCGDTKMPETSQTCHLLPCTSWKPSHWSPCSVTCGSGIQTRSV
Sbjct: 1261 RERTTECIYREQSVDASFCGDTKMPETSQTCHLLPCTSWKPSHWSPCSVTCGSGIQTRSV 1320
Query: 981 SCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACS 802
SCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACS
Sbjct: 1321 SCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACS 1380
Query: 801 ATCGNGTQRRLLKCRDHVRDLPDEYCNHLDKEVSTRNCRLRDCSYWKMAEWEECPATCGT 622
ATCGNGTQRRLLKCRDHVRDLPDEYCNHLDKEVSTRNCRLRDCSYWKMAEWEECPATCGT
Sbjct: 1381 ATCGNGTQRRLLKCRDHVRDLPDEYCNHLDKEVSTRNCRLRDCSYWKMAEWEECPATCGT 1440
Query: 621 HVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPKGEEHIGSWIIGDWSK 442
HVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPKGEEHIGSWIIGDWSK
Sbjct: 1441 HVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPKGEEHIGSWIIGDWSK 1500
Query: 441 CSASCGGGWXXXXXXXXXXXCDETRKPKMFDKCNEELCPPLTNNSWQISPWTHCSVSCGG 262
CSASCGGGW CDETRKPKMFDKCNEELCPPLTNNSWQISPWTHCSVSCGG
Sbjct: 1501 CSASCGGGWRRRSVSCTSSSCDETRKPKMFDKCNEELCPPLTNNSWQISPWTHCSVSCGG 1560
Query: 261 GVQRRKIWCEDVLSGRKQDDIECSEIKPREQRDCEMPPCRSHYHNKXXXXXXXXXXXXXX 82
GVQRRKIWCEDVLSGRKQDDIECSEIKPREQRDCEMPPCRSHYHNK
Sbjct: 1561 GVQRRKIWCEDVLSGRKQDDIECSEIKPREQRDCEMPPCRSHYHNKTSSASMTSLSSSNS 1620
Query: 81 XXXXXXXXXXLPILPPVVSWQTSAWSA 1
LPILPPVVSWQTSAWSA
Sbjct: 1621 NTTSSASASSLPILPPVVSWQTSAWSA 1647
Score = 312 bits (799), Expect = 6e-83
Identities = 224/831 (26%), Positives = 326/831 (38%), Gaps = 137/831 (16%)
Frame = -1
Query: 2214 WTECDRACRGQQSQK-LMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRWITEDVS 2038
W+EC R+C G + CLD + R++H C P Q CN T W S
Sbjct: 1084 WSECSRSCDGGVKMRHAQCLD-AADRETHTSRCG----PAQTQEHCNEHACTWWQFGVWS 1138
Query: 2037 SCSAKCGSGQKRQRVSC-------------VKMEGDRQTPASEHLCDRNSKPSDIASCYI 1897
CSAKCG G + + +C +KME P C + K + + C +
Sbjct: 1139 DCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIITKPCHRESCPKY-KLGEWSQCSV 1197
Query: 1896 DC----SGRK------------------------------------WNYGEWTSCSETCG 1837
C S R+ W +W++CS +CG
Sbjct: 1198 SCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNTDWSACSVSCG 1257
Query: 1836 SNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWVYGHWSECSRSCDGGV 1657
G R + C+ + VD S CG + T + C+ +PC W HWS CS +C G+
Sbjct: 1258 I-GHRERTTECIY-REQSVDASFCGDTKMPETSQTCHLLPCTSWKPSHWSPCSVTCGSGI 1315
Query: 1656 KMRHAQCLDAADR----ETHTSRCGPAQTQEHCNEHACTW---------------WQFGV 1534
+ R C ++ E R + ++ C + C W G
Sbjct: 1316 QTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGP 1375
Query: 1533 WSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEK-IITKPCHRESCPKYKLGEWSQC 1357
W+ CSA CG+G Q R C D R LP+ C ++K + T+ C C +K+ EW +C
Sbjct: 1376 WTACSATCGNGTQRRLLKCRDHVRD-LPDEYCNHLDKEVSTRNCRLRDCSYWKMAEWEEC 1434
Query: 1356 SVSCEDG-WSSRRVSCVSGN--GTEVDMSLCGTASDRPASHQTCNLGTCP-------FWR 1207
+C SR V+CVS G + + RP S + C L CP W
Sbjct: 1435 PATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPKGEEHIGSWI 1494
Query: 1206 NTDWSACSVSCGIGHRERTTECIYREQSVDASFCGDTKMPETSQTCHLLPC-----TSWK 1042
DWS CS SCG G R R+ C +S C +T+ P+ C+ C SW+
Sbjct: 1495 IGDWSKCSASCGGGWRRRSVSCT-------SSSCDETRKPKMFDKCNEELCPPLTNNSWQ 1547
Query: 1041 PSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQ 862
S W+ CSV+CG G+Q R + C G D+ C +PR ++ CE C +
Sbjct: 1548 ISPWTHCSVSCGGGVQRRKIWCEDVLSGRKQDDIECSE-IKPREQRDCEMPPCRSHYHNK 1606
Query: 861 KLQADV-----------------------PPIRWATGPWTACSATCGNGTQRRLLKCRDH 751
A + P + W T W+ACSA CG GT+RR+++C +
Sbjct: 1607 TSSASMTSLSSSNSNTTSSASASSLPILPPVVSWQTSAWSACSAKCGRGTKRRVVECVNP 1666
Query: 750 VRDLP--DEYCNHLDKEVSTRNCRLRDCSYWKMAEWEECPATCGTHVQQSRNVTCVSAED 577
++ C+ K V CR + C WK W C TCG +++ R V C
Sbjct: 1667 SLNVTVASTECDQTKKPVEEVRCRTKHCPRWKTTTWSSCSVTCGRGIRR-REVQCYR--- 1722
Query: 576 GGRTILKDVDCDVQKRPTSARNCRLEPCPKGEEHIGSWIIGDWSKCSASCGGGWXXXXXX 397
G + ++ D +C+ + + S NC CP W + WSKC C G
Sbjct: 1723 GRKNLVSDSECNPKTKLNSVANCFPVACPAYR-----WNVTPWSKCKDECARGQKQTRRV 1777
Query: 396 XXXXXCDETRKPKMFD---------KCNEELCPPLTNNSWQISPWTHCSVSCGGGVQRRK 244
+ P+M + +C+ CP W W CS SCG GVQ R+
Sbjct: 1778 HCISTSGKRAAPRMCELARAPTSIRECDTSNCP----YEWVPGDWQTCSKSCGEGVQTRE 1833
Query: 243 IWCEDVLSGRKQDDI------------ECSEI--KPREQRDCEMPPCRSHY 133
+ C ++ I E E+ KP E + CE+ PC S +
Sbjct: 1834 VRCRRKINFNSTIPIIFMLEDEPAVPKEKCELFPKPNESQTCELNPCDSEF 1884
Score = 301 bits (772), Expect = 8e-80
Identities = 215/792 (27%), Positives = 309/792 (38%), Gaps = 107/792 (13%)
Frame = -1
Query: 2214 WTECDRACR-GQQSQKLMCL-------DMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTR 2059
W++C +C G S+++ C+ DMS + DR + + CN+
Sbjct: 1192 WSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASH--------QTCNLGTCPF 1243
Query: 2058 WITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYI-DCSGR 1882
W D S+CS CG G + + C+ R+ C P +C++ C+
Sbjct: 1244 WRNTDWSACSVSCGIGHRERTTECIY----REQSVDASFCGDTKMPETSQTCHLLPCTS- 1298
Query: 1881 KWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCP--- 1711
W W+ CS TCGS + S VDE C R + ++ C + C
Sbjct: 1299 -WKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPR 1357
Query: 1710 ------------RWVYGHWSECSRSCDGGVKMRHAQCLDAADRETHTSRCGPAQTQ---E 1576
RW G W+ CS +C G + R +C D R+ C +
Sbjct: 1358 VLQKLQADVPPIRWATGPWTACSATCGNGTQRRLLKCRDHV-RDLPDEYCNHLDKEVSTR 1416
Query: 1575 HCNEHACTWWQFGVWSDCSAKCGDGVQY-RDANCT---DRHRSVLPEHRC-LKMEKIITK 1411
+C C++W+ W +C A CG VQ R+ C D R++L + C ++ +
Sbjct: 1417 NCRLRDCSYWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSAR 1476
Query: 1410 PCHRESCPK-------YKLGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRP 1252
C E CPK + +G+WS+CS SC GW R VSC S + E + +P
Sbjct: 1477 NCRLEPCPKGEEHIGSWIIGDWSKCSASCGGGWRRRSVSCTSSSCDE---------TRKP 1527
Query: 1251 ASHQTCNLGTCP-----FWRNTDWSACSVSCGIGHRERTTEC--IYREQSVDASFCGDTK 1093
CN CP W+ + W+ CSVSCG G + R C + + D C + K
Sbjct: 1528 KMFDKCNEELCPPLTNNSWQISPWTHCSVSCGGGVQRRKIWCEDVLSGRKQDDIECSEIK 1587
Query: 1092 MPETSQTCHLLPC--------------------------------------TSWKPSHWS 1027
P + C + PC SW+ S WS
Sbjct: 1588 -PREQRDCEMPPCRSHYHNKTSSASMTSLSSSNSNTTSSASASSLPILPPVVSWQTSAWS 1646
Query: 1026 PCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQAD 847
CS CG G + R V C S V CD+ +P + C C
Sbjct: 1647 ACSAKCGRGTKRRVVECVNPSLNVTVASTECDQTKKPVEEVRCRTKHCP----------- 1695
Query: 846 VPPIRWATGPWTACSATCGNGTQRRLLKC-RDHVRDLPDEYCNHLDKEVSTRNCRLRDCS 670
RW T W++CS TCG G +RR ++C R + D CN K S NC C
Sbjct: 1696 ----RWKTTTWSSCSVTCGRGIRRREVQCYRGRKNLVSDSECNPKTKLNSVANCFPVACP 1751
Query: 669 --YWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEP 496
W + W +C C +Q+R V C+S G R + C++ + PTS R C
Sbjct: 1752 AYRWNVTPWSKCKDECARGQKQTRRVHCIST-SGKRAAPR--MCELARAPTSIRECDTSN 1808
Query: 495 CPKGEEHIGSWIIGDWSKCSASCGGGWXX------------XXXXXXXXXCDETRKPK-- 358
CP W+ GDW CS SCG G DE PK
Sbjct: 1809 CPY------EWVPGDWQTCSKSCGEGVQTREVRCRRKINFNSTIPIIFMLEDEPAVPKEK 1862
Query: 357 --MFDKCNE----ELCPPLTNNSWQISPWTHCSVSCGGGVQRRKIWCEDVLSGRKQDDIE 196
+F K NE EL P + W PW CS +CG G++RR++ C GR+ + ++
Sbjct: 1863 CELFPKPNESQTCELNPCDSEFKWSFGPWGECSKNCGQGIRRRRVKCV-ANDGRRVERVK 1921
Query: 195 CSEIKPREQRDC 160
C+ KPR + C
Sbjct: 1922 CTTKKPRRTQYC 1933
Score = 135 bits (339), Expect = 1e-29
Identities = 119/499 (23%), Positives = 182/499 (35%), Gaps = 64/499 (12%)
Frame = -1
Query: 2232 WRVTDTWTECDRACRGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATR----MCNIDCS 2065
W + D W++C +C G ++ + S+ C KPK + +C +
Sbjct: 1493 WIIGD-WSKCSASCGGGWRRRSVSCTSSS--------CDETRKPKMFDKCNEELCPPLTN 1543
Query: 2064 TRWITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQT---------PASEHLCDR------- 1933
W + CS CG G +R+++ C + R+ P + C+
Sbjct: 1544 NSWQISPWTHCSVSCGGGVQRRKIWCEDVLSGRKQDDIECSEIKPREQRDCEMPPCRSHY 1603
Query: 1932 NSKPSDIASCYIDCSGRK------------------WNYGEWTSCSETCGSNGKMHRKSY 1807
++K S + + S W W++CS CG G R
Sbjct: 1604 HNKTSSASMTSLSSSNSNTTSSASASSLPILPPVVSWQTSAWSACSAKCG-RGTKRRVVE 1662
Query: 1806 CVDDS-NRRVDESLCGREQKEATERECNRIPCPRWVYGHWSECSRSCDGGVKMRHAQCLD 1630
CV+ S N V + C + +K E C CPRW WS CS +C G++ R QC
Sbjct: 1663 CVNPSLNVTVASTECDQTKKPVEEVRCRTKHCPRWKTTTWSSCSVTCGRGIRRREVQCYR 1722
Query: 1629 AADRETHTSRCGP---AQTQEHCNEHACTWWQFGV--WSDCSAKCGDG-VQYRDANCTDR 1468
S C P + +C AC +++ V WS C +C G Q R +C
Sbjct: 1723 GRKNLVSDSECNPKTKLNSVANCFPVACPAYRWNVTPWSKCKDECARGQKQTRRVHCIST 1782
Query: 1467 HRSVLPEHRC-LKMEKIITKPCHRESCP-KYKLGEWSQCSVSCEDGWSSRRVSCVSGNGT 1294
C L + C +CP ++ G+W CS SC +G +R V C
Sbjct: 1783 SGKRAAPRMCELARAPTSIRECDTSNCPYEWVPGDWQTCSKSCGEGVQTREVRCRRKINF 1842
Query: 1293 EVDMSLCGTASDRPA-------------SHQTCNLGTCPF---WRNTDWSACSVSCGIGH 1162
+ + D PA QTC L C W W CS +CG G
Sbjct: 1843 NSTIPIIFMLEDEPAVPKEKCELFPKPNESQTCELNPCDSEFKWSFGPWGECSKNCGQGI 1902
Query: 1161 RERTTECIYRE-QSVDASFCGDTKMPETSQTCHLLPCTSWKPSHWSPCSVTCGSGIQTRS 985
R R +C+ + + V+ C TK P +Q C C S C ++ +
Sbjct: 1903 RRRRVKCVANDGRRVERVKC-TTKKPRRTQYCFERNCLP------STCQELKSQNVKAKD 1955
Query: 984 VSCTRGSEGTIVDEYFCDR 928
+ T +G + E +C R
Sbjct: 1956 GNYTILLDGFTI-EIYCHR 1973
Score = 84.0 bits (206), Expect = 3e-14
Identities = 56/202 (27%), Positives = 90/202 (43%), Gaps = 21/202 (10%)
Frame = -1
Query: 2256 PISSALYLWRVTDTWTEC-DRACRGQ-QSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRM 2083
P++ Y W VT W++C D RGQ Q++++ C+ S R + R C+ P
Sbjct: 1747 PVACPAYRWNVTP-WSKCKDECARGQKQTRRVHCISTSGKRAA-PRMCELARAPTSIREC 1804
Query: 2082 CNIDCSTRWITEDVSSCSAKCGSGQKRQRVSCVK-------------MEGDRQTPASEHL 1942
+C W+ D +CS CG G + + V C + +E + P +
Sbjct: 1805 DTSNCPYEWVPGDWQTCSKSCGEGVQTREVRCRRKINFNSTIPIIFMLEDEPAVPKEK-- 1862
Query: 1941 CDRNSKPSDIASCYID-CSGR-KWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESL 1768
C+ KP++ +C ++ C KW++G W CS+ CG G R+ CV + RRV+
Sbjct: 1863 CELFPKPNESQTCELNPCDSEFKWSFGPWGECSKNCG-QGIRRRRVKCVANDGRRVERVK 1921
Query: 1767 CGREQKEAT----ERECNRIPC 1714
C ++ T ER C C
Sbjct: 1922 CTTKKPRRTQYCFERNCLPSTC 1943
>gi|39585757|emb|CAE59959.1| Hypothetical protein CBG03449
[Caenorhabditis briggsae]
Length = 2153
Score = 3138 bits (8136), Expect = 0.0
Identities = 1452/1649 (88%), Positives = 1517/1649 (91%), Gaps = 2/1649 (0%)
Frame = -1
Query: 4941 MRSIGGSFHXXXXXXXXXXXXXXXXXXXLQSGSGTISEFSS-DVLFSRAKYSGVPVHHSR 4765
MRSIGGSFH LQSGSG+ + SS DVLFSRAKYSGVPVHHSR
Sbjct: 1 MRSIGGSFHLLQPFVAALLLLVVCLVYALQSGSGSTTTLSSPDVLFSRAKYSGVPVHHSR 60
Query: 4764 WRQDAGIHVIDSHHIVRRDSYGRRGKRDVTSTDRRRRLQGVARDCGHACHLRLRSDDAVY 4585
WR DAGIH+IDSHHIVRRDS+GRRGKRDV ++ R L GVARDCGHACHLRLRSDDAVY
Sbjct: 61 WRHDAGIHIIDSHHIVRRDSHGRRGKRDVRTSGPR--LHGVARDCGHACHLRLRSDDAVY 118
Query: 4584 IVHLHRWNQIPDSHNKSVPHFSNSNFAPMVLYLDSEEEVRGGMSRTDPDCIYRAHVKGVH 4405
IVHLHRWNQIPDSHNKSVPHF+NSN+ PMVLYLDSEEEVRGGM RTDPDCIYRAHVKGVH
Sbjct: 119 IVHLHRWNQIPDSHNKSVPHFANSNYQPMVLYLDSEEEVRGGMGRTDPDCIYRAHVKGVH 178
Query: 4404 QHSIVNLCDSEDGLYGMLALPSGIHTVEPIISGNGTEHDGASRHRQHLVRKFDPMHFKSF 4225
QHSIVNLCDS+DGLYGMLALPSGIHTVEPIISGNGT+ DGA RHRQHLVRKFDPMHFKSF
Sbjct: 179 QHSIVNLCDSDDGLYGMLALPSGIHTVEPIISGNGTD-DGAGRHRQHLVRKFDPMHFKSF 237
Query: 4224 DHLNSTSVNETETTVATWQDQWEDVIERKARSRRAANSWDHYVEVLVVADTKMYEYHGRS 4045
DHLNSTSV+E ETTVATWQD+WEDVIERKARSRRAANSWDHYVEVLVVADTKMYEYHGRS
Sbjct: 238 DHLNSTSVSEAETTVATWQDKWEDVIERKARSRRAANSWDHYVEVLVVADTKMYEYHGRS 297
Query: 4044 LEDYVLTLFSTVASIYRHQSLRASXXXXXXXXXXXKTENAGPRITQNAQQTLQDFCRWQQ 3865
LEDYVLTLFSTVASIYRHQSL+AS KTENAGPRITQNAQQTLQDFC+WQQ
Sbjct: 298 LEDYVLTLFSTVASIYRHQSLKASINVVVVKLIVLKTENAGPRITQNAQQTLQDFCKWQQ 357
Query: 3864 YYNDPDDSSVQHHDVAILLTRKDICRSQGKCDTLGLAELGTMCDMQKSCAIIEDNGLSAA 3685
YYNDPDDSSVQHHDVAILLTRKDICRSQGKCDTLGLAELGTMCD+QKSCAIIEDNGLSAA
Sbjct: 358 YYNDPDDSSVQHHDVAILLTRKDICRSQGKCDTLGLAELGTMCDLQKSCAIIEDNGLSAA 417
Query: 3684 FTIAHELGHVFSIPHDDERKCSTYMPVNKVCK-FQSTKFDKTQFQNNFHIMAPTLEYNTH 3508
FTIAHELGHVFSIPHDDERKCS+YM VNKV + + +F QNNFHIMAPTLEYNTH
Sbjct: 418 FTIAHELGHVFSIPHDDERKCSSYMQVNKVIRDIEMNRF----IQNNFHIMAPTLEYNTH 473
Query: 3507 PWSWSPCSAGMLERFLENNRGQTQCLFDQPVERRYYEDVFVRDEPGKKYDAHQQCKFVFG 3328
PWSWSPCSAGMLERFLENNRGQTQCLFDQPVERRYYEDVFVRDEPGKKYDAHQQCKFVFG
Sbjct: 474 PWSWSPCSAGMLERFLENNRGQTQCLFDQPVERRYYEDVFVRDEPGKKYDAHQQCKFVFG 533
Query: 3327 PASELCPYMPTCRRLWCATFYGSQMGCRTQHMPWADGTPCDESRSMFCHHGACVRLAPES 3148
PASELCPYMPTCRRLWCATFYGSQMGCRTQHMPWADGTPCDESR+MFCHHGACVRLA ES
Sbjct: 534 PASELCPYMPTCRRLWCATFYGSQMGCRTQHMPWADGTPCDESRNMFCHHGACVRLAAES 593
Query: 3147 LTKIDGQWGDWRSWGECSRTCGGGVQKGLRDCDSPKPRNGGKYCVGQRERYRSCNTQECP 2968
LTK+DGQWGDW WG CSRTCGGGVQK LRDCDSPKPRNGGKYCVGQRERYRSCNTQECP
Sbjct: 594 LTKVDGQWGDWMDWGTCSRTCGGGVQKALRDCDSPKPRNGGKYCVGQRERYRSCNTQECP 653
Query: 2967 WDTQPYREVQCSEFNNKDIGIQGVASTNTHWVPKYANVAPNERCKLYCRLSGSAAFYLLR 2788
WDTQPYRE+QC+EFNNKDIGIQGVASTNT WVPKYANVAPNERCKLYCRLSGSAAFYLL+
Sbjct: 654 WDTQPYRELQCAEFNNKDIGIQGVASTNTIWVPKYANVAPNERCKLYCRLSGSAAFYLLK 713
Query: 2787 DKVVDGTPCDRNGDDICVAGACMPAGCDHQLHSTLRRDKCGVCGGDDSSCKVVKGTFNEQ 2608
DKVVDGTPCDRNGDDICVAGACMPAGCDHQLHSTLRRDKCGVCGG+DSSCKVVKGTFNEQ
Sbjct: 714 DKVVDGTPCDRNGDDICVAGACMPAGCDHQLHSTLRRDKCGVCGGNDSSCKVVKGTFNEQ 773
Query: 2607 GTFGYNEVMKIPAGSANIDIRQKGYNNMKEDDNYLSLRAANGEFLLNGHFQVSLARQQIA 2428
GTFGYNEVMKIPAGSANIDIRQKGYNNMKEDDNYLSLRAANGEFLLNGHFQVSLARQQIA
Sbjct: 774 GTFGYNEVMKIPAGSANIDIRQKGYNNMKEDDNYLSLRAANGEFLLNGHFQVSLARQQIA 833
Query: 2427 FQDTVLEYSGSDAIIERINGTGPIRSDIYVHVLSVGSHPPDISYEYMTAAVPNAVIRPIS 2248
FQDTVLEYSGSDA+IERINGTGPIRSDIYVHVLSVGSHPPDISYEYMTAAVPNAV+RPIS
Sbjct: 834 FQDTVLEYSGSDAVIERINGTGPIRSDIYVHVLSVGSHPPDISYEYMTAAVPNAVVRPIS 893
Query: 2247 SALYLWRVTDTWTECDRACRGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDC 2068
SALYLWR T++W++CDRACRGQQ+QKLMC+DMSTHRQSHDRNCQNVLKPKQATRMCNIDC
Sbjct: 894 SALYLWRPTESWSDCDRACRGQQTQKLMCVDMSTHRQSHDRNCQNVLKPKQATRMCNIDC 953
Query: 2067 STRWITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYIDCS 1888
STRWITEDVS+C+AKCGSGQKRQRVSCVKMEGDRQTP SEHLCDRN+KP++I SCY+DCS
Sbjct: 954 STRWITEDVSTCNAKCGSGQKRQRVSCVKMEGDRQTPVSEHLCDRNTKPAEITSCYVDCS 1013
Query: 1887 GRKWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPR 1708
GR+W+YGEWT+CSETCGSNGKMHRKSYCVD SNRRVDESLCGREQKE TERECNRIPCPR
Sbjct: 1014 GRRWSYGEWTTCSETCGSNGKMHRKSYCVDGSNRRVDESLCGREQKEGTERECNRIPCPR 1073
Query: 1707 WVYGHWSECSRSCDGGVKMRHAQCLDAADRETHTSRCGPAQTQEHCNEHACTWWQFGVWS 1528
WVYGHW ECSRSCDGGV+MRHAQCLDAADRETH SRCGPA T E CNEHACTWWQFGVWS
Sbjct: 1074 WVYGHW-ECSRSCDGGVRMRHAQCLDAADRETHNSRCGPAHTHEACNEHACTWWQFGVWS 1132
Query: 1527 DCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIITKPCHRESCPKYKLGEWSQCSVS 1348
+CS KCGDGVQYRD+NCTDRH SVL EHRC KMEKI+TK CHRE CPKYKLGEWSQCSVS
Sbjct: 1133 ECSVKCGDGVQYRDSNCTDRHGSVLQEHRCNKMEKILTKQCHREPCPKYKLGEWSQCSVS 1192
Query: 1347 CEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNTDWSACSVSCGI 1168
CEDGWSSRRVSCV+GNGTEVD+SLCG ASDRPASHQTCNLGTCPFWR TDWSACSVSCGI
Sbjct: 1193 CEDGWSSRRVSCVAGNGTEVDISLCGPASDRPASHQTCNLGTCPFWRTTDWSACSVSCGI 1252
Query: 1167 GHRERTTECIYREQSVDASFCGDTKMPETSQTCHLLPCTSWKPSHWSPCSVTCGSGIQTR 988
GHRERT ECIYR+QSVD+SFCGD+K+PET QTCHLLPCTSWKPSHWSPCSVTCGSGIQTR
Sbjct: 1253 GHRERTIECIYRDQSVDSSFCGDSKLPETRQTCHLLPCTSWKPSHWSPCSVTCGSGIQTR 1312
Query: 987 SVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTA 808
SVSC RGSEG +VDEYFCDRNTRPR KK+CEKDTC+GPRVLQKLQADVPPIRWATGPWTA
Sbjct: 1313 SVSCIRGSEGNVVDEYFCDRNTRPREKKSCEKDTCEGPRVLQKLQADVPPIRWATGPWTA 1372
Query: 807 CSATCGNGTQRRLLKCRDHVRDLPDEYCNHLDKEVSTRNCRLRDCSYWKMAEWEECPATC 628
CSATCGNGTQRRLLKCRDHVRDLPDEYC+HL+KEVSTRNC LRDCS+WK EWE+CPATC
Sbjct: 1373 CSATCGNGTQRRLLKCRDHVRDLPDEYCSHLEKEVSTRNCHLRDCSFWKSGEWEDCPATC 1432
Query: 627 GTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPKGEEHIGSWIIGDW 448
GTHVQQSRNV+CVSAED G+TIL+D DCDVQKRPTS RNCRLEPCPKGEEHIGSWIIGDW
Sbjct: 1433 GTHVQQSRNVSCVSAEDSGKTILRDTDCDVQKRPTSTRNCRLEPCPKGEEHIGSWIIGDW 1492
Query: 447 SKCSASCGGGWXXXXXXXXXXXCDETRKPKMFDKCNEELCPPLTNNSWQISPWTHCSVSC 268
SKCSASCGGGW CDETRKPKMFDKCNEELCPPLTNNSWQISPWTHCSVSC
Sbjct: 1493 SKCSASCGGGWRRRSVSCTSASCDETRKPKMFDKCNEELCPPLTNNSWQISPWTHCSVSC 1552
Query: 267 GGGVQRRKIWCEDVLSGRKQDDIECSEIKPREQRDCEMPPCRSHYHNKXXXXXXXXXXXX 88
GGGVQRR+IWCEDVLSGRKQDD EC E+KPREQRDCEMPPCRS NK
Sbjct: 1553 GGGVQRRRIWCEDVLSGRKQDDTECFEVKPREQRDCEMPPCRSRPINK------TSSSSI 1606
Query: 87 XXXXXXXXXXXXLPILPPVVSWQTSAWSA 1
LPILPPVVSWQ+SAWSA
Sbjct: 1607 SSDSTSSASASLLPILPPVVSWQSSAWSA 1635
Score = 313 bits (802), Expect = 3e-83
Identities = 223/780 (28%), Positives = 321/780 (40%), Gaps = 80/780 (10%)
Frame = -1
Query: 2232 WRVTDTWTECDRACR-GQQSQKLMCLDM-STHRQSHDRNCQNVLKPKQATRMCNIDCSTR 2059
W W+EC C G Q + C D + Q H N K T+ C+ + +
Sbjct: 1125 WWQFGVWSECSVKCGDGVQYRDSNCTDRHGSVLQEHRCNKME----KILTKQCHREPCPK 1180
Query: 2058 WITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNS-KPSDIASCYIDCSGR 1882
+ + S CS C G +RVSCV G T LC S +P+ +C +
Sbjct: 1181 YKLGEWSQCSVSCEDGWSSRRVSCVAGNG---TEVDISLCGPASDRPASHQTCNLGTCPF 1237
Query: 1881 KWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWV 1702
W +W++CS +CG G R C+ ++ VD S CG + T + C+ +PC W
Sbjct: 1238 -WRTTDWSACSVSCGI-GHRERTIECIY-RDQSVDSSFCGDSKLPETRQTCHLLPCTSWK 1294
Query: 1701 YGHWSECSRSCDGGVKMRHAQCLDAADR----ETHTSRCGPAQTQEHCNEHACTW----- 1549
HWS CS +C G++ R C+ ++ E R + ++ C + C
Sbjct: 1295 PSHWSPCSVTCGSGIQTRSVSCIRGSEGNVVDEYFCDRNTRPREKKSCEKDTCEGPRVLQ 1354
Query: 1548 ----------WQFGVWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEK-IITKPCH 1402
W G W+ CSA CG+G Q R C D R LP+ C +EK + T+ CH
Sbjct: 1355 KLQADVPPIRWATGPWTACSATCGNGTQRRLLKCRDHVRD-LPDEYCSHLEKEVSTRNCH 1413
Query: 1401 RESCPKYKLGEWSQCSVSCEDG-WSSRRVSCVSG--NGTEVDMSLCGTASDRPASHQTCN 1231
C +K GEW C +C SR VSCVS +G + RP S + C
Sbjct: 1414 LRDCSFWKSGEWEDCPATCGTHVQQSRNVSCVSAEDSGKTILRDTDCDVQKRPTSTRNCR 1473
Query: 1230 LGTCP-------FWRNTDWSACSVSCGIGHRERTTECIYREQSVDASFCGDTKMPETSQT 1072
L CP W DWS CS SCG G R R+ C ++ C +T+ P+
Sbjct: 1474 LEPCPKGEEHIGSWIIGDWSKCSASCGGGWRRRSVSCT-------SASCDETRKPKMFDK 1526
Query: 1071 CHLLPC-----TSWKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLK 907
C+ C SW+ S W+ CSV+CG G+Q R + C G D+ C +PR +
Sbjct: 1527 CNEELCPPLTNNSWQISPWTHCSVSCGGGVQRRRIWCEDVLSGRKQDDTECFE-VKPREQ 1585
Query: 906 KTCEKDTCDGPRVLQKLQADV-----------------PPIRWATGPWTACSATCGNGTQ 778
+ CE C + + + + P + W + W+ACSA CG GT+
Sbjct: 1586 RDCEMPPCRSRPINKTSSSSISSDSTSSASASLLPILPPVVSWQSSAWSACSAKCGRGTK 1645
Query: 777 RRLLKCRDHVRD--LPDEYCNHLDKEVSTRNCRLRDCSYWKMAEWEECPATCGTHVQQSR 604
RR+++C + + + C+ K V CR + C WK W C TCG V++ R
Sbjct: 1646 RRVVECVNPSLNVTIASTECDQTKKPVEEIRCRTKHCPKWKATAWSSCSVTCGRGVRR-R 1704
Query: 603 NVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPKGEEHIGSWIIGDWSKCSASCG 424
+V C G + + D +C+ + + S NC CP + W I WSKC C
Sbjct: 1705 DVQCYR---GRKNHVADSECNDKTKLHSVANCFPVACPAYK-----WNITPWSKCKDECA 1756
Query: 423 GGWXXXXXXXXXXXCDETRKPKMFD---------KCNEELCPPLTNNSWQISPWTHCSVS 271
G + P+M D +C+ CP W W CS S
Sbjct: 1757 RGQKQTRRVHCVSTSGKRAAPRMCDVSRAPISVRECDTSNCP----YEWVPGDWQTCSKS 1812
Query: 270 CGGGVQRRKIWCED------------VLSGRKQDDIECSEI--KPREQRDCEMPPCRSHY 133
CG GVQ R + C +L E E+ KP E + CE+ PC S +
Sbjct: 1813 CGEGVQTRDVRCRRKDNFNTTVPIIFMLEDEPAVPKEKCEMFPKPIESQVCELNPCDSEF 1872
Score = 309 bits (792), Expect = 4e-82
Identities = 217/787 (27%), Positives = 316/787 (39%), Gaps = 102/787 (12%)
Frame = -1
Query: 2214 WTECDRACR-GQQSQKLMCL-------DMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTR 2059
W++C +C G S+++ C+ D+S + DR + + CN+
Sbjct: 1186 WSQCSVSCEDGWSSRRVSCVAGNGTEVDISLCGPASDRPASH--------QTCNLGTCPF 1237
Query: 2058 WITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYI-DCSGR 1882
W T D S+CS CG G + + + C+ R C + P +C++ C+
Sbjct: 1238 WRTTDWSACSVSCGIGHRERTIECIY----RDQSVDSSFCGDSKLPETRQTCHLLPCTS- 1292
Query: 1881 KWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRV-DESLCGREQKEATERECNRIPCP-- 1711
W W+ CS TCGS G R C+ S V DE C R + ++ C + C
Sbjct: 1293 -WKPSHWSPCSVTCGS-GIQTRSVSCIRGSEGNVVDEYFCDRNTRPREKKSCEKDTCEGP 1350
Query: 1710 -------------RWVYGHWSECSRSCDGGVKMRHAQCLDAADRETHTSRCGPAQTQ--- 1579
RW G W+ CS +C G + R +C D R+ C + +
Sbjct: 1351 RVLQKLQADVPPIRWATGPWTACSATCGNGTQRRLLKCRDHV-RDLPDEYCSHLEKEVST 1409
Query: 1578 EHCNEHACTWWQFGVWSDCSAKCGDGVQY-RDANCT---DRHRSVLPEHRC-LKMEKIIT 1414
+C+ C++W+ G W DC A CG VQ R+ +C D +++L + C ++ T
Sbjct: 1410 RNCHLRDCSFWKSGEWEDCPATCGTHVQQSRNVSCVSAEDSGKTILRDTDCDVQKRPTST 1469
Query: 1413 KPCHRESCPK-------YKLGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDR 1255
+ C E CPK + +G+WS+CS SC GW R VSC S + E + +
Sbjct: 1470 RNCRLEPCPKGEEHIGSWIIGDWSKCSASCGGGWRRRSVSCTSASCDE---------TRK 1520
Query: 1254 PASHQTCNLGTCP-----FWRNTDWSACSVSCGIGHRERTTEC--IYREQSVDASFCGDT 1096
P CN CP W+ + W+ CSVSCG G + R C + + D + C +
Sbjct: 1521 PKMFDKCNEELCPPLTNNSWQISPWTHCSVSCGGGVQRRRIWCEDVLSGRKQDDTECFEV 1580
Query: 1095 KMPETSQTCHLLPC--------------------------------TSWKPSHWSPCSVT 1012
K P + C + PC SW+ S WS CS
Sbjct: 1581 K-PREQRDCEMPPCRSRPINKTSSSSISSDSTSSASASLLPILPPVVSWQSSAWSACSAK 1639
Query: 1011 CGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIR 832
CG G + R V C S + CD+ +P + C C +
Sbjct: 1640 CGRGTKRRVVECVNPSLNVTIASTECDQTKKPVEEIRCRTKHCP---------------K 1684
Query: 831 WATGPWTACSATCGNGTQRRLLKC-RDHVRDLPDEYCNHLDKEVSTRNCRLRDCSY--WK 661
W W++CS TCG G +RR ++C R + D CN K S NC C W
Sbjct: 1685 WKATAWSSCSVTCGRGVRRRDVQCYRGRKNHVADSECNDKTKLHSVANCFPVACPAYKWN 1744
Query: 660 MAEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPKGE 481
+ W +C C +Q+R V CVS G R + CDV + P S R C CP
Sbjct: 1745 ITPWSKCKDECARGQKQTRRVHCVSTS-GKRAAPRM--CDVSRAPISVRECDTSNCPY-- 1799
Query: 480 EHIGSWIIGDWSKCSASCGGGWXXXXXXXXXXXCDETRKPKMF----------DKCNE-- 337
W+ GDW CS SCG G T P +F +KC
Sbjct: 1800 ----EWVPGDWQTCSKSCGEGVQTRDVRCRRKDNFNTTVPIIFMLEDEPAVPKEKCEMFP 1855
Query: 336 --------ELCPPLTNNSWQISPWTHCSVSCGGGVQRRKIWCEDVLSGRKQDDIECSEIK 181
EL P + W PW CS +CG G++RR++ C GR+ + I+C+ K
Sbjct: 1856 KPIESQVCELNPCDSEFKWSFGPWGECSKNCGQGIRRRRVKCV-ANDGRRVERIKCTTKK 1914
Query: 180 PREQRDC 160
PR + C
Sbjct: 1915 PRRTQYC 1921
Score = 272 bits (696), Expect = 5e-71
Identities = 201/729 (27%), Positives = 290/729 (39%), Gaps = 90/729 (12%)
Frame = -1
Query: 2232 WRVTDTWTECDRACR-GQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRW 2056
WR TD W+ C +C G + + + C+ QS D + K + + C++ T W
Sbjct: 1238 WRTTD-WSACSVSCGIGHRERTIECIYRD---QSVDSSFCGDSKLPETRQTCHLLPCTSW 1293
Query: 2055 ITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYID-CSGRK 1879
S CS CGSG + + VSC++ G E+ CDRN++P + SC D C G +
Sbjct: 1294 KPSHWSPCSVTCGSGIQTRSVSCIR--GSEGNVVDEYFCDRNTRPREKKSCEKDTCEGPR 1351
Query: 1878 -------------WNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATE 1738
W G WT+CS TCG NG R C D DE C +KE +
Sbjct: 1352 VLQKLQADVPPIRWATGPWTACSATCG-NGTQRRLLKCRDHVRDLPDE-YCSHLEKEVST 1409
Query: 1737 RECNRIPCPRWVYGHWSECSRSCDGGVKM-RHAQCLDAAD------RETHTSRCGPAQTQ 1579
R C+ C W G W +C +C V+ R+ C+ A D R+T +
Sbjct: 1410 RNCHLRDCSFWKSGEWEDCPATCGTHVQQSRNVSCVSAEDSGKTILRDTDCDVQKRPTST 1469
Query: 1578 EHCNEHACTW-------WQFGVWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKI 1420
+C C W G WS CSA CG G + R +CT + E R KM
Sbjct: 1470 RNCRLEPCPKGEEHIGSWIIGDWSKCSASCGGGWRRRSVSCTS---ASCDETRKPKM--- 1523
Query: 1419 ITKPCHRESCP-----KYKLGEWSQCSVSCEDGWSSRRVSCVSG-NGTEVDMSLCGTASD 1258
C+ E CP +++ W+ CSVSC G RR+ C +G + D + C
Sbjct: 1524 -FDKCNEELCPPLTNNSWQISPWTHCSVSCGGGVQRRRIWCEDVLSGRKQDDTECFEV-- 1580
Query: 1257 RPASHQTCNLGTCPF--------------------------------WRNTDWSACSVSC 1174
+P + C + C W+++ WSACS C
Sbjct: 1581 KPREQRDCEMPPCRSRPINKTSSSSISSDSTSSASASLLPILPPVVSWQSSAWSACSAKC 1640
Query: 1173 GIGHRERTTECIYREQSVD--ASFCGDTKMPETSQTCHLLPCTSWKPSHWSPCSVTCGSG 1000
G G + R EC+ +V ++ C TK P C C WK + WS CSVTCG G
Sbjct: 1641 GRGTKRRVVECVNPSLNVTIASTECDQTKKPVEEIRCRTKHCPKWKATAWSSCSVTCGRG 1700
Query: 999 IQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATG 820
++ R V C RG + + D C+ T+ C C P +W
Sbjct: 1701 VRRRDVQCYRGRKNHVADSE-CNDKTKLHSVANCFPVAC-------------PAYKWNIT 1746
Query: 819 PWTACSATCGNGTQ--RRLLKCRDHVRDLPDEYCNHLDKEVSTRNCRLRDCSY-WKMAEW 649
PW+ C C G + RR+ + C+ +S R C +C Y W +W
Sbjct: 1747 PWSKCKDECARGQKQTRRVHCVSTSGKRAAPRMCDVSRAPISVRECDTSNCPYEWVPGDW 1806
Query: 648 EECPATCGTHVQQSRNVTCVSAEDGGRTI-----LKD------VDCDVQKRPTSARNCRL 502
+ C +CG V Q+R+V C ++ T+ L+D C++ +P ++ C L
Sbjct: 1807 QTCSKSCGEGV-QTRDVRCRRKDNFNTTVPIIFMLEDEPAVPKEKCEMFPKPIESQVCEL 1865
Query: 501 EPCPKGEEHIGSWIIGDWSKCSASCGGG-------WXXXXXXXXXXXCDETRKPKMFDKC 343
PC + W G W +CS +CG G T+KP+ C
Sbjct: 1866 NPC----DSEFKWSFGPWGECSKNCGQGIRRRRVKCVANDGRRVERIKCTTKKPRRTQYC 1921
Query: 342 NEELCPPLT 316
E C P T
Sbjct: 1922 FERNCLPST 1930
Score = 142 bits (357), Expect = 1e-31
Identities = 88/335 (26%), Positives = 136/335 (40%), Gaps = 23/335 (6%)
Frame = -1
Query: 2271 NAVIRPISSALYLWRVTDTWTECDRAC-RGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQ 2095
+A + PI + W+ + W+ C C RG + + + C++ S + C KP +
Sbjct: 1615 SASLLPILPPVVSWQ-SSAWSACSAKCGRGTKRRVVECVNPSLNVTIASTECDQTKKPVE 1673
Query: 2094 ATRMCNIDCSTRWITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSD 1915
R C +W SSCS CG G +R+ V C + R+ ++ C+ +K
Sbjct: 1674 EIR-CRTKHCPKWKATAWSSCSVTCGRGVRRRDVQCYR---GRKNHVADSECNDKTKLHS 1729
Query: 1914 IASCY-IDCSGRKWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATE 1738
+A+C+ + C KWN W+ C + C K R+ +CV S +R +C + +
Sbjct: 1730 VANCFPVACPAYKWNITPWSKCKDECARGQKQTRRVHCVSTSGKRAAPRMCDVSRAPISV 1789
Query: 1737 RECNRIPCP-RWVYGHWSECSRSCDGGVKMRHAQCLDAADRETHTS-----RCGPAQTQE 1576
REC+ CP WV G W CS+SC GV+ R +C + T PA +E
Sbjct: 1790 RECDTSNCPYEWVPGDWQTCSKSCGEGVQTRDVRCRRKDNFNTTVPIIFMLEDEPAVPKE 1849
Query: 1575 HCN-------EHACTW--------WQFGVWSDCSAKCGDGVQYRDANCTDRHRSVLPEHR 1441
C C W FG W +CS CG G++ R C + +
Sbjct: 1850 KCEMFPKPIESQVCELNPCDSEFKWSFGPWGECSKNCGQGIRRRRVKCVANDGRRVERIK 1909
Query: 1440 CLKMEKIITKPCHRESCPKYKLGEWSQCSVSCEDG 1336
C + T+ C +C E S DG
Sbjct: 1910 CTTKKPRRTQYCFERNCLPSTCQELKSLSGKARDG 1944
>gi|33624896|ref|NP_891550.1| a disintegrin and metalloproteinase with
thrombospondin motifs 9 isoform 1 preproprotein [Homo
sapiens]
Length = 1935
Score = 998 bits (2581), Expect = 0.0
Identities = 557/1587 (35%), Positives = 795/1587 (49%), Gaps = 156/1587 (9%)
Frame = -1
Query: 4437 CIYRAHVKGVHQHS-IVNLCDSEDGLYGMLALPSGIHTVEPIISGNGTEHDGASRHRQHL 4261
C Y+ +V +H+ +++LC G+ G G + +EP+ S + E D +++ H+
Sbjct: 150 CFYKGYVNTNSEHTAVISLCS---GMLGTFRSHDGDYFIEPLQSMDEQE-DEEEQNKPHI 205
Query: 4260 V-RKFDPMHFKSF--------DHLNSTSVNETETTVATWQDQWE---------------- 4156
+ R+ P S +H N S ++ +T W ++
Sbjct: 206 IYRRSAPQREPSTGRHACDTSEHKNRHSKDKKKTRARKWGERINLAGDVAALNSGLATEA 265
Query: 4155 --------DVIERKARSRRAAN--SWDHYVEVLVVADTKMYEYHGRSLEDYVLTLFSTVA 4006
D K RR S+ +VEVLVVAD +M YHG +L+ Y+LTL S VA
Sbjct: 266 FSAYGNKTDNTREKRTHRRTKRFLSYPRFVEVLVVADNRMVSYHGENLQHYILTLMSIVA 325
Query: 4005 SIYRHQSLRASXXXXXXXXXXXKTENAGPRITQNAQQTLQDFCRWQQYYNDPDDSSVQHH 3826
SIY+ S+ E GP I+ NAQ TL++FC+WQ N P HH
Sbjct: 326 SIYKDPSIGNLINIVIVNLIVIHNEQDGPSISFNAQTTLKNFCQWQHSKNSPGGI---HH 382
Query: 3825 DVAILLTRKDICRSQGKCDTLGLAELGTMCDMQKSCAIIEDNGLSAAFTIAHELGHVFSI 3646
D A+LLTR+DICR+ KCDTLGLAELGT+CD +SC+I ED+GLS AFTIAHELGHVF++
Sbjct: 383 DTAVLLTRQDICRAHDKCDTLGLAELGTICDPYRSCSISEDSGLSTAFTIAHELGHVFNM 442
Query: 3645 PHDDERKCSTYMPVNKVCKFQSTKFDKTQFQNNFHIMAPTLEYNTHPWSWSPCSAGMLER 3466
PHDD KC K + K + H+MAPTL + T+PW WS CS +
Sbjct: 443 PHDDNNKC----------KEEGVKSPQ-------HVMAPTLNFYTNPWMWSKCSRKYITE 485
Query: 3465 FLENNRGQTQCLFDQPVERRYYEDVFVRDEPGKKYDAHQQCKFVFGPASELCPYMPTCRR 3286
FL+ G+ CL ++P R Y V + PG Y+ ++QC+ +FGP S++CPYM CRR
Sbjct: 486 FLDTGYGE--CLLNEPESRPYPLPVQL---PGILYNVNKQCELIFGPGSQVCPYMMQCRR 540
Query: 3285 LWCATFYGSQMGCRTQHMPWADGTPCDESRSMFCHHGACVRLAPESLTKIDGQWGDWRSW 3106
LWC G GCRTQH PWADGT C+ + C +G CV + + DG WG W +
Sbjct: 541 LWCNNVNGVHKGCRTQHTPWADGTECEPGKH--CKYGFCVPKEMD-VPVTDGSWGSWSPF 597
Query: 3105 GECSRTCGGGVQKGLRDCDSPKPRNGGKYCVGQRERYRSCNTQECPWDTQPYREVQCSEF 2926
G CSRTCGGG++ +R+C+ P+P+NGGKYCVG+R +++SCNT+ C + +R+ QC+ F
Sbjct: 598 GTCSRTCGGGIKTAIRECNRPEPKNGGKYCVGRRMKFKSCNTEPCLKQKRDFRDEQCAHF 657
Query: 2925 NNKDIGIQGVASTNTHWVPKYANVAPNERCKLYCRLSGSAAFYLLRDKVVDGTPCDRNGD 2746
+ K I G+ N WVPKY+ + +RCKL+CR++G+ A+Y LRD+V+DGTPC ++ +
Sbjct: 658 DGKHFNINGLLP-NVRWVPKYSGILMKDRCKLFCRVAGNTAYYQLRDRVIDGTPCGQDTN 716
Query: 2745 DICVAGACMPAGCDHQLHSTLRRDKCGVCGGDDSSCKVVKGTFNEQGTFGYNEVMKIPAG 2566
DICV G C AGCDH L+S RRDKCGVCGGD+SSCK V GTFN +GYN V++IPAG
Sbjct: 717 DICVQGLCRQAGCDHVLNSKARRDKCGVCGGDNSSCKTVAGTFNTV-HYGYNTVVRIPAG 775
Query: 2565 SANIDIRQKGYNNMKEDDNYLSLRAANGEFLLNGHFQVSLARQQIAFQDTVLEYSGSDAI 2386
+ NID+RQ ++ +DDNYL+L ++ GEFLLNG+F V++A+++I + V+EYSGS+
Sbjct: 776 ATNIDVRQHSFSGETDDDNYLALSSSKGEFLLNGNFVVTMAKREIRIGNAVVEYSGSETA 835
Query: 2385 IERINGTGPIRSDIYVHVLSVGS-HPPDISYEYMTAAVPNAVIRPISSALYLWRVTDTWT 2209
+ERIN T I ++ + VLSVG + PD+ Y + N I Y W W
Sbjct: 836 VERINSTDRIEQELLLQVLSVGKLYNPDVRYSF------NIPIEDKPQQFY-WNSHGPWQ 888
Query: 2208 ECDRACRGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRWITEDVSSCS 2029
C + C+G++ +KL+C S D+ C + +P T C DC RW S CS
Sbjct: 889 ACSKPCQGERKRKLVCTRESDQLTVSDQRCDRLPQPGHITEPCGTDCDLRWHVASRSECS 948
Query: 2028 AKCGSGQKRQRVSCVKME--GDRQTPASEHLCDRNSKPSDIASCYIDCSGRKWNYGEWTS 1855
A+CG G + + C K + + C + KPS+ C +C+ W Y WT
Sbjct: 949 AQCGLGYRTLDIYCAKYSRLDGKTEKVDDGFCSSHPKPSNREKCSGECNTGGWRYSAWTE 1008
Query: 1854 CSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWVYGHWSECSR 1675
CS++C G R++ CV+ N +D+S C ++K +R C+ PCP+W G WSEC
Sbjct: 1009 CSKSC-DGGTQRRRAICVNTRNDVLDDSKCTHQEKVTIQR-CSEFPCPQWKSGDWSECLV 1066
Query: 1674 SCDGGVKMRHAQCLDAADRETHTSRCGP---AQTQEHCNEHACTWWQFGVWSDCSAKCGD 1504
+C G K R C DR + C P + + C + C WQ G W CS CG
Sbjct: 1067 TCGKGHKHRQVWCQFGEDR-LNDRMCDPETKPTSMQTCQQPECASWQAGPWGQCSVTCGQ 1125
Query: 1503 GVQYRDANC-TDRHRSVLPEHRC-LKMEKIITKPCHRESC------------------PK 1384
G Q R C + SV+ ++ C T+ C SC +
Sbjct: 1126 GYQLRAVKCIIGTYMSVVDDNDCNAATRPTDTQDCELPSCHPPPAAPETRRSTYSAPRTQ 1185
Query: 1383 YKLGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRN 1204
++ G W+ CS +C G R VSC NG+ D S C T RP + + C++ C W+
Sbjct: 1186 WRFGSWTPCSATCGKGTRMRYVSCRDENGSVADESACATL-PRPVAKEECSVTPCGQWKA 1244
Query: 1203 TDWSACSVSCGIGHRERTTECI-YREQSVDASFCGDTKMPETSQTCHLLPC--------- 1054
DWS+CSV+CG G R C+ Y + +D S C +PET Q C + PC
Sbjct: 1245 LDWSSCSVTCGQGRATRQVMCVNYSDHVIDRSECDQDYIPETDQDCSMSPCPQRTPDSGL 1304
Query: 1053 -------------------------TSWKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIV 949
W+ W CS TC G Q R V C + T
Sbjct: 1305 AQHPFQNEDYRPRSASPSRTHVLGGNQWRTGPWGACSSTCAGGSQRRVVVCQDENGYTAN 1364
Query: 948 DEYFCDRNTRPRLKKTCEKDTCD--------------GPRVLQKLQA------------- 850
D C +P ++ CE C G + +L
Sbjct: 1365 D---CVERIKPDEQRACESGPCPQWAYGNWGECTKLCGGGIRTRLVVCQRSNGERFPDLS 1421
Query: 849 ----DVPPIR-------------WATGPWTACSATCGNGTQRRLLKC-RDHVRDLPDEYC 724
D PP R W+TGPW++CS +CG G ++R + C L +YC
Sbjct: 1422 CEILDKPPDREQCNTHACPHDAAWSTGPWSSCSVSCGRGHKQRNVYCMAKDGSHLESDYC 1481
Query: 723 NHLDKEVSTRNCRLRDCSYWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDC 544
HL K R CR C WK W +C +CG VQQ R+V C + G I ++ +C
Sbjct: 1482 KHLAKPHGHRKCRGGRCPKWKAGAWSQCSVSCGRGVQQ-RHVGC---QIGTHKIARETEC 1537
Query: 543 DVQKRPTSARNCRLEPCPKGEEHIGSWIIGDWSKCSASCGGGWXXXXXXXXXXXCDE--- 373
+ RP S R+C+ CP + +W +W +C+ +CG G +E
Sbjct: 1538 NPYTRPESERDCQGPRCP-----LYTWRAEEWQECTKTCGEGSRYRKVVCVDDNKNEVHG 1592
Query: 372 -----TRKPKMFDKCNEELCPPLTNNSWQISPWTHCSVSCGGGVQRRKIWCEDVLSGRK- 211
+++P + C+ + C + W W+ CSV+CG G ++R + C ++ +G++
Sbjct: 1593 ARCDVSKRPVDRESCSLQPCEYV----WITGEWSECSVTCGKGYKQRLVSCSEIYTGKEN 1648
Query: 210 -----QDDIECSEIKPREQRDCEMPPC 145
Q I C +P C + C
Sbjct: 1649 YEYSYQTTINCPGTQPPSVHPCYLRDC 1675
Score = 256 bits (653), Expect = 5e-66
Identities = 174/646 (26%), Positives = 267/646 (40%), Gaps = 76/646 (11%)
Frame = -1
Query: 2214 WTECDRAC-RGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCS--------- 2065
W +C C +G Q + + C+ + D +C +P T+ C +
Sbjct: 1116 WGQCSVTCGQGYQLRAVKCIIGTYMSVVDDNDCNAATRPTD-TQDCELPSCHPPPAAPET 1174
Query: 2064 ---------TRWITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDI 1912
T+W + CSA CG G + + VSC G + A E C +P
Sbjct: 1175 RRSTYSAPRTQWRFGSWTPCSATCGKGTRMRYVSCRDENG---SVADESACATLPRPVAK 1231
Query: 1911 ASCYIDCSGRKWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERE 1732
C + G+ W +W+SCS TCG G+ R+ CV+ S+ +D S C ++ T+++
Sbjct: 1232 EECSVTPCGQ-WKALDWSSCSVTCGQ-GRATRQVMCVNYSDHVIDRSECDQDYIPETDQD 1289
Query: 1731 CNRIPCPR----------------------------------WVYGHWSECSRSCDGGVK 1654
C+ PCP+ W G W CS +C GG +
Sbjct: 1290 CSMSPCPQRTPDSGLAQHPFQNEDYRPRSASPSRTHVLGGNQWRTGPWGACSSTCAGGSQ 1349
Query: 1653 MRHAQCLDAADRETH--TSRCGPAQTQEHCNEHACTWWQFGVWSDCSAKCGDGVQYRDAN 1480
R C D + R P + Q C C W +G W +C+ CG G++ R
Sbjct: 1350 RRVVVCQDENGYTANDCVERIKPDE-QRACESGPCPQWAYGNWGECTKLCGGGIRTRLVV 1408
Query: 1479 CTDRHRSVLPEHRCLKMEKIITKP-----CHRESCPK---YKLGEWSQCSVSCEDGWSSR 1324
C + P+ C +I+ KP C+ +CP + G WS CSVSC G R
Sbjct: 1409 CQRSNGERFPDLSC----EILDKPPDREQCNTHACPHDAAWSTGPWSSCSVSCGRGHKQR 1464
Query: 1323 RVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNTDWSACSVSCGIGHRERTTE 1144
V C++ +G+ ++ C + +P H+ C G CP W+ WS CSVSCG G ++R
Sbjct: 1465 NVYCMAKDGSHLESDYCKHLA-KPHGHRKCRGGRCPKWKAGAWSQCSVSCGRGVQQRHVG 1523
Query: 1143 C-IYREQSVDASFCGDTKMPETSQTCH--LLPCTSWKPSHWSPCSVTCGSGIQTRSVSCT 973
C I + + C PE+ + C P +W+ W C+ TCG G + R V C
Sbjct: 1524 CQIGTHKIARETECNPYTRPESERDCQGPRCPLYTWRAEEWQECTKTCGEGSRYRKVVCV 1583
Query: 972 RGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATC 793
++ + CD + RP +++C C+ W TG W+ CS TC
Sbjct: 1584 DDNKNEVHGAR-CDVSKRPVDRESCSLQPCE--------------YVWITGEWSECSVTC 1628
Query: 792 GNGTQRRLLKCRDHVRDLPD-EYCNHL------DKEVSTRNCRLRDC---SYWKMAEWEE 643
G G ++RL+ C + + EY + S C LRDC + W++ W
Sbjct: 1629 GKGYKQRLVSCSEIYTGKENYEYSYQTTINCPGTQPPSVHPCYLRDCPVSATWRVGNWGS 1688
Query: 642 CPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCR 505
C +CG V Q R+V C++ ED + C +P + CR
Sbjct: 1689 CSVSCGVGVMQ-RSVQCLTNEDQPSHL-----CHTDLKPEERKTCR 1728
Score = 195 bits (495), Expect = 1e-47
Identities = 120/410 (29%), Positives = 178/410 (43%), Gaps = 22/410 (5%)
Frame = -1
Query: 2232 WRVTDTWTECDRACRG-QQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRW 2056
WR T W C C G Q + ++C D + + + +C +KP + R C +W
Sbjct: 1332 WR-TGPWGACSSTCAGGSQRRVVVCQDENGYTAN---DCVERIKPDEQ-RACESGPCPQW 1386
Query: 2055 ITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYIDCSGRK- 1879
+ C+ CG G + + V C + G+R S C+ KP D C
Sbjct: 1387 AYGNWGECTKLCGGGIRTRLVVCQRSNGERFPDLS---CEILDKPPDREQCNTHACPHDA 1443
Query: 1878 -WNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWV 1702
W+ G W+SCS +CG G R YC+ ++ C K R+C CP+W
Sbjct: 1444 AWSTGPWSSCSVSCG-RGHKQRNVYCMAKDGSHLESDYCKHLAKPHGHRKCRGGRCPKWK 1502
Query: 1701 YGHWSECSRSCDGGVKMRHAQCLDAADRETHTSRCGP---AQTQEHCNEHACTW--WQFG 1537
G WS+CS SC GV+ RH C + + C P +++ C C W+
Sbjct: 1503 AGAWSQCSVSCGRGVQQRHVGCQIGTHKIARETECNPYTRPESERDCQGPRCPLYTWRAE 1562
Query: 1536 VWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIITKPCHRESCPK------YKL 1375
W +C+ CG+G +YR C D +++ + RC + +P RESC +
Sbjct: 1563 EWQECTKTCGEGSRYRKVVCVDDNKNEVHGARC----DVSKRPVDRESCSLQPCEYVWIT 1618
Query: 1374 GEWSQCSVSCEDGWSSRRVSCVS-----GNGTEVDMSLCGTASDRPASHQTCNLGTCPF- 1213
GEWS+CSV+C G+ R VSC N + +P S C L CP
Sbjct: 1619 GEWSECSVTCGKGYKQRLVSCSEIYTGKENYEYSYQTTINCPGTQPPSVHPCYLRDCPVS 1678
Query: 1212 --WRNTDWSACSVSCGIGHRERTTECIYREQSVDASFCGDTKMPETSQTC 1069
WR +W +CSVSCG+G +R+ +C+ E + C PE +TC
Sbjct: 1679 ATWRVGNWGSCSVSCGVGVMQRSVQCLTNEDQ-PSHLCHTDLKPEERKTC 1727
>gi|32130427|sp|Q9P2N4|ATS9_HUMAN ADAMTS-9 precursor (A disintegrin
and metalloproteinase with thrombospondin motifs 9)
(ADAM-TS 9) (ADAM-TS9)
Length = 1935
Score = 998 bits (2579), Expect = 0.0
Identities = 557/1587 (35%), Positives = 795/1587 (49%), Gaps = 156/1587 (9%)
Frame = -1
Query: 4437 CIYRAHVKGVHQHS-IVNLCDSEDGLYGMLALPSGIHTVEPIISGNGTEHDGASRHRQHL 4261
C Y+ +V +H+ +++LC G+ G G + +EP+ S + E D +++ H+
Sbjct: 150 CFYKGYVNTNSEHTAVISLCS---GMLGTFRSHDGDYFIEPLQSMDEQE-DEEEQNKPHI 205
Query: 4260 V-RKFDPMHFKSF--------DHLNSTSVNETETTVATWQDQWE---------------- 4156
+ R+ P S +H N S ++ +T W ++
Sbjct: 206 IYRRSAPQREPSTGRHACDTSEHKNRHSKDKKKTRARKWGERINLAGDVAALNSGLATEA 265
Query: 4155 --------DVIERKARSRRAAN--SWDHYVEVLVVADTKMYEYHGRSLEDYVLTLFSTVA 4006
D K RR S+ +VEVLVVAD +M YHG +L+ Y+LTL S VA
Sbjct: 266 FSAYGNKTDNTREKRTHRRTKRFLSYPRFVEVLVVADNRMVSYHGENLQHYILTLMSIVA 325
Query: 4005 SIYRHQSLRASXXXXXXXXXXXKTENAGPRITQNAQQTLQDFCRWQQYYNDPDDSSVQHH 3826
SIY+ S+ E GP I+ NAQ TL++FC+WQ N P HH
Sbjct: 326 SIYKDPSIGNLINIVIVNLIVIHNEQDGPSISFNAQTTLKNFCQWQHSKNSPGGI---HH 382
Query: 3825 DVAILLTRKDICRSQGKCDTLGLAELGTMCDMQKSCAIIEDNGLSAAFTIAHELGHVFSI 3646
D A+LLTR+DICR+ KCDTLGLAELGT+CD +SC+I ED+GLS AFTIAHELGHVF++
Sbjct: 383 DTAVLLTRQDICRAHDKCDTLGLAELGTICDPYRSCSISEDSGLSTAFTIAHELGHVFNM 442
Query: 3645 PHDDERKCSTYMPVNKVCKFQSTKFDKTQFQNNFHIMAPTLEYNTHPWSWSPCSAGMLER 3466
PHDD KC K + K + H+MAPTL + T+PW WS CS +
Sbjct: 443 PHDDNNKC----------KEEGVKSPQ-------HVMAPTLNFYTNPWMWSKCSRKYITE 485
Query: 3465 FLENNRGQTQCLFDQPVERRYYEDVFVRDEPGKKYDAHQQCKFVFGPASELCPYMPTCRR 3286
FL+ G+ CL ++P R Y V + PG Y+ ++QC+ +FGP S++CPYM CRR
Sbjct: 486 FLDTGYGE--CLLNEPESRPYPLPVQL---PGILYNVNKQCELIFGPGSQVCPYMMQCRR 540
Query: 3285 LWCATFYGSQMGCRTQHMPWADGTPCDESRSMFCHHGACVRLAPESLTKIDGQWGDWRSW 3106
LWC G GCRTQH PWADGT C+ + C +G CV + + DG WG W +
Sbjct: 541 LWCNNVNGVHKGCRTQHTPWADGTECEPGKH--CKYGFCVPKEMD-VPVTDGSWGSWSPF 597
Query: 3105 GECSRTCGGGVQKGLRDCDSPKPRNGGKYCVGQRERYRSCNTQECPWDTQPYREVQCSEF 2926
G CSRTCGGG++ +R+C+ P+P+NGGKYCVG+R +++SCNT+ C + +R+ QC+ F
Sbjct: 598 GTCSRTCGGGIKTAIRECNRPEPKNGGKYCVGRRMKFKSCNTEPCLKQKRDFRDEQCAHF 657
Query: 2925 NNKDIGIQGVASTNTHWVPKYANVAPNERCKLYCRLSGSAAFYLLRDKVVDGTPCDRNGD 2746
+ K I G+ N WVPKY+ + +RCKL+CR++G+ A+Y LRD+V+DGTPC ++ +
Sbjct: 658 DGKHFNINGLLP-NVRWVPKYSGILMKDRCKLFCRVAGNTAYYQLRDRVIDGTPCGQDTN 716
Query: 2745 DICVAGACMPAGCDHQLHSTLRRDKCGVCGGDDSSCKVVKGTFNEQGTFGYNEVMKIPAG 2566
DICV G C AGCDH L+S RRDKCGVCGGD+SSCK V GTFN +GYN V++IPAG
Sbjct: 717 DICVQGLCRQAGCDHVLNSKARRDKCGVCGGDNSSCKTVAGTFNTV-HYGYNTVVRIPAG 775
Query: 2565 SANIDIRQKGYNNMKEDDNYLSLRAANGEFLLNGHFQVSLARQQIAFQDTVLEYSGSDAI 2386
+ NID+RQ ++ +DDNYL+L ++ GEFLLNG+F V++A+++I + V+EYSGS+
Sbjct: 776 ATNIDVRQHSFSGETDDDNYLALSSSKGEFLLNGNFVVTMAKREIRIGNAVVEYSGSETA 835
Query: 2385 IERINGTGPIRSDIYVHVLSVGS-HPPDISYEYMTAAVPNAVIRPISSALYLWRVTDTWT 2209
+ERIN T I ++ + VLSVG + PD+ Y + N I Y W W
Sbjct: 836 VERINSTDRIEQELLLQVLSVGKLYNPDVRYSF------NIPIEDKPQQFY-WNSHGPWQ 888
Query: 2208 ECDRACRGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRWITEDVSSCS 2029
C + C+G++ +KL+C S D+ C + +P T C DC RW S CS
Sbjct: 889 ACSKPCQGERKRKLVCTRESDQLTVSDQRCDRLPQPGHITEPCGTDCDLRWHVASRSECS 948
Query: 2028 AKCGSGQKRQRVSCVKME--GDRQTPASEHLCDRNSKPSDIASCYIDCSGRKWNYGEWTS 1855
A+CG G + + C K + + C + KPS+ C +C+ W Y WT
Sbjct: 949 AQCGLGYRTLDIYCAKYSRLDGKTEKVDDGFCSSHPKPSNREKCSGECNTGGWRYSAWTE 1008
Query: 1854 CSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWVYGHWSECSR 1675
CS++C G R++ CV+ N +D+S C ++K +R C+ PCP+W G WSEC
Sbjct: 1009 CSKSC-DGGTQRRRAICVNTRNDVLDDSKCTHQEKVTIQR-CSEFPCPQWKSGDWSECLV 1066
Query: 1674 SCDGGVKMRHAQCLDAADRETHTSRCGP---AQTQEHCNEHACTWWQFGVWSDCSAKCGD 1504
+C G K R C DR + C P + + C + C WQ G W CS CG
Sbjct: 1067 TCGKGHKHRQVWCQFGEDR-LNDRMCDPETKPTSMQTCQQPECASWQAGPWVQCSVTCGQ 1125
Query: 1503 GVQYRDANC-TDRHRSVLPEHRC-LKMEKIITKPCHRESC------------------PK 1384
G Q R C + SV+ ++ C T+ C SC +
Sbjct: 1126 GYQLRAVKCIIGTYMSVVDDNDCNAATRPTDTQDCELPSCHPPPAAPETRRSTYSAPRTQ 1185
Query: 1383 YKLGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRN 1204
++ G W+ CS +C G R VSC NG+ D S C T RP + + C++ C W+
Sbjct: 1186 WRFGSWTPCSATCGKGTRMRYVSCRDENGSVADESACATL-PRPVAKEECSVTPCGQWKA 1244
Query: 1203 TDWSACSVSCGIGHRERTTECI-YREQSVDASFCGDTKMPETSQTCHLLPC--------- 1054
DWS+CSV+CG G R C+ Y + +D S C +PET Q C + PC
Sbjct: 1245 LDWSSCSVTCGQGRATRQVMCVNYSDHVIDRSECDQDYIPETDQDCSMSPCPQRTPDSGL 1304
Query: 1053 -------------------------TSWKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIV 949
W+ W CS TC G Q R V C + T
Sbjct: 1305 AQHPFQNEDYRPRSASPSRTHVLGGNQWRTGPWGACSSTCAGGSQRRVVVCQDENGYTAN 1364
Query: 948 DEYFCDRNTRPRLKKTCEKDTCD--------------GPRVLQKLQA------------- 850
D C +P ++ CE C G + +L
Sbjct: 1365 D---CVERIKPDEQRACESGPCPQWAYGNWGECTKLCGGGIRTRLVVCQRSNGERFPDLS 1421
Query: 849 ----DVPPIR-------------WATGPWTACSATCGNGTQRRLLKC-RDHVRDLPDEYC 724
D PP R W+TGPW++CS +CG G ++R + C L +YC
Sbjct: 1422 CEILDKPPDREQCNTHACPHDAAWSTGPWSSCSVSCGRGHKQRNVYCMAKDGSHLESDYC 1481
Query: 723 NHLDKEVSTRNCRLRDCSYWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDC 544
HL K R CR C WK W +C +CG VQQ R+V C + G I ++ +C
Sbjct: 1482 KHLAKPHGHRKCRGGRCPKWKAGAWSQCSVSCGRGVQQ-RHVGC---QIGTHKIARETEC 1537
Query: 543 DVQKRPTSARNCRLEPCPKGEEHIGSWIIGDWSKCSASCGGGWXXXXXXXXXXXCDE--- 373
+ RP S R+C+ CP + +W +W +C+ +CG G +E
Sbjct: 1538 NPYTRPESERDCQGPRCP-----LYTWRAEEWQECTKTCGEGSRYRKVVCVDDNKNEVHG 1592
Query: 372 -----TRKPKMFDKCNEELCPPLTNNSWQISPWTHCSVSCGGGVQRRKIWCEDVLSGRK- 211
+++P + C+ + C + W W+ CSV+CG G ++R + C ++ +G++
Sbjct: 1593 ARCDVSKRPVDRESCSLQPCEYV----WITGEWSECSVTCGKGYKQRLVSCSEIYTGKEN 1648
Query: 210 -----QDDIECSEIKPREQRDCEMPPC 145
Q I C +P C + C
Sbjct: 1649 YEYSYQTTINCPGTQPPSVHPCYLREC 1675
Score = 255 bits (651), Expect = 9e-66
Identities = 173/646 (26%), Positives = 267/646 (40%), Gaps = 76/646 (11%)
Frame = -1
Query: 2214 WTECDRAC-RGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCS--------- 2065
W +C C +G Q + + C+ + D +C +P T+ C +
Sbjct: 1116 WVQCSVTCGQGYQLRAVKCIIGTYMSVVDDNDCNAATRPTD-TQDCELPSCHPPPAAPET 1174
Query: 2064 ---------TRWITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDI 1912
T+W + CSA CG G + + VSC G + A E C +P
Sbjct: 1175 RRSTYSAPRTQWRFGSWTPCSATCGKGTRMRYVSCRDENG---SVADESACATLPRPVAK 1231
Query: 1911 ASCYIDCSGRKWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERE 1732
C + G+ W +W+SCS TCG G+ R+ CV+ S+ +D S C ++ T+++
Sbjct: 1232 EECSVTPCGQ-WKALDWSSCSVTCGQ-GRATRQVMCVNYSDHVIDRSECDQDYIPETDQD 1289
Query: 1731 CNRIPCPR----------------------------------WVYGHWSECSRSCDGGVK 1654
C+ PCP+ W G W CS +C GG +
Sbjct: 1290 CSMSPCPQRTPDSGLAQHPFQNEDYRPRSASPSRTHVLGGNQWRTGPWGACSSTCAGGSQ 1349
Query: 1653 MRHAQCLDAADRETH--TSRCGPAQTQEHCNEHACTWWQFGVWSDCSAKCGDGVQYRDAN 1480
R C D + R P + Q C C W +G W +C+ CG G++ R
Sbjct: 1350 RRVVVCQDENGYTANDCVERIKPDE-QRACESGPCPQWAYGNWGECTKLCGGGIRTRLVV 1408
Query: 1479 CTDRHRSVLPEHRCLKMEKIITKP-----CHRESCPK---YKLGEWSQCSVSCEDGWSSR 1324
C + P+ C +I+ KP C+ +CP + G WS CSVSC G R
Sbjct: 1409 CQRSNGERFPDLSC----EILDKPPDREQCNTHACPHDAAWSTGPWSSCSVSCGRGHKQR 1464
Query: 1323 RVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNTDWSACSVSCGIGHRERTTE 1144
V C++ +G+ ++ C + +P H+ C G CP W+ WS CSVSCG G ++R
Sbjct: 1465 NVYCMAKDGSHLESDYCKHLA-KPHGHRKCRGGRCPKWKAGAWSQCSVSCGRGVQQRHVG 1523
Query: 1143 C-IYREQSVDASFCGDTKMPETSQTCH--LLPCTSWKPSHWSPCSVTCGSGIQTRSVSCT 973
C I + + C PE+ + C P +W+ W C+ TCG G + R V C
Sbjct: 1524 CQIGTHKIARETECNPYTRPESERDCQGPRCPLYTWRAEEWQECTKTCGEGSRYRKVVCV 1583
Query: 972 RGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATC 793
++ + CD + RP +++C C+ W TG W+ CS TC
Sbjct: 1584 DDNKNEVHGAR-CDVSKRPVDRESCSLQPCE--------------YVWITGEWSECSVTC 1628
Query: 792 GNGTQRRLLKCRDHVRDLPD-EYCNHL------DKEVSTRNCRLRDC---SYWKMAEWEE 643
G G ++RL+ C + + EY + S C LR+C + W++ W
Sbjct: 1629 GKGYKQRLVSCSEIYTGKENYEYSYQTTINCPGTQPPSVHPCYLRECPVSATWRVGNWGS 1688
Query: 642 CPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCR 505
C +CG V Q R+V C++ ED + C +P + CR
Sbjct: 1689 CSVSCGVGVMQ-RSVQCLTNEDQPSHL-----CHTDLKPEERKTCR 1728
Score = 195 bits (495), Expect = 1e-47
Identities = 120/410 (29%), Positives = 178/410 (43%), Gaps = 22/410 (5%)
Frame = -1
Query: 2232 WRVTDTWTECDRACRG-QQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRW 2056
WR T W C C G Q + ++C D + + + +C +KP + R C +W
Sbjct: 1332 WR-TGPWGACSSTCAGGSQRRVVVCQDENGYTAN---DCVERIKPDEQ-RACESGPCPQW 1386
Query: 2055 ITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYIDCSGRK- 1879
+ C+ CG G + + V C + G+R S C+ KP D C
Sbjct: 1387 AYGNWGECTKLCGGGIRTRLVVCQRSNGERFPDLS---CEILDKPPDREQCNTHACPHDA 1443
Query: 1878 -WNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWV 1702
W+ G W+SCS +CG G R YC+ ++ C K R+C CP+W
Sbjct: 1444 AWSTGPWSSCSVSCG-RGHKQRNVYCMAKDGSHLESDYCKHLAKPHGHRKCRGGRCPKWK 1502
Query: 1701 YGHWSECSRSCDGGVKMRHAQCLDAADRETHTSRCGP---AQTQEHCNEHACTW--WQFG 1537
G WS+CS SC GV+ RH C + + C P +++ C C W+
Sbjct: 1503 AGAWSQCSVSCGRGVQQRHVGCQIGTHKIARETECNPYTRPESERDCQGPRCPLYTWRAE 1562
Query: 1536 VWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIITKPCHRESCPK------YKL 1375
W +C+ CG+G +YR C D +++ + RC + +P RESC +
Sbjct: 1563 EWQECTKTCGEGSRYRKVVCVDDNKNEVHGARC----DVSKRPVDRESCSLQPCEYVWIT 1618
Query: 1374 GEWSQCSVSCEDGWSSRRVSCVS-----GNGTEVDMSLCGTASDRPASHQTCNLGTCPF- 1213
GEWS+CSV+C G+ R VSC N + +P S C L CP
Sbjct: 1619 GEWSECSVTCGKGYKQRLVSCSEIYTGKENYEYSYQTTINCPGTQPPSVHPCYLRECPVS 1678
Query: 1212 --WRNTDWSACSVSCGIGHRERTTECIYREQSVDASFCGDTKMPETSQTC 1069
WR +W +CSVSCG+G +R+ +C+ E + C PE +TC
Sbjct: 1679 ATWRVGNWGSCSVSCGVGVMQRSVQCLTNEDQ-PSHLCHTDLKPEERKTC 1727
>gi|27463365|gb|AAO15765.1| a disintegrin-like and metalloprotease
with thrombospondin type 1 motifs 9B [Homo sapiens]
Length = 1935
Score = 997 bits (2578), Expect = 0.0
Identities = 557/1587 (35%), Positives = 795/1587 (49%), Gaps = 156/1587 (9%)
Frame = -1
Query: 4437 CIYRAHVKGVHQHS-IVNLCDSEDGLYGMLALPSGIHTVEPIISGNGTEHDGASRHRQHL 4261
C Y+ +V +H+ +++LC G+ G G + +EP+ S + E D +++ H+
Sbjct: 150 CFYKGYVNTNSEHTAVISLCS---GMLGTFRSHDGGYFIEPLQSMDEQE-DEEEQNKPHI 205
Query: 4260 V-RKFDPMHFKSF--------DHLNSTSVNETETTVATWQDQWE---------------- 4156
+ R+ P S +H N S ++ +T W ++
Sbjct: 206 IYRRSAPQREPSTGRHACDTSEHKNRHSKDKKKTRARKWGERINLAGDVAALNSGLATEA 265
Query: 4155 --------DVIERKARSRRAAN--SWDHYVEVLVVADTKMYEYHGRSLEDYVLTLFSTVA 4006
D K RR S+ +VEVLVVAD +M YHG +L+ Y+LTL S VA
Sbjct: 266 FSAYGNKTDNTREKRTHRRTKRFLSYPRFVEVLVVADNRMVSYHGENLQHYILTLMSIVA 325
Query: 4005 SIYRHQSLRASXXXXXXXXXXXKTENAGPRITQNAQQTLQDFCRWQQYYNDPDDSSVQHH 3826
SIY+ S+ E GP I+ NAQ TL++FC+WQ N P HH
Sbjct: 326 SIYKDPSIGNLINIVIVNLIVIHNEQDGPSISFNAQTTLKNFCQWQHSKNSPGGI---HH 382
Query: 3825 DVAILLTRKDICRSQGKCDTLGLAELGTMCDMQKSCAIIEDNGLSAAFTIAHELGHVFSI 3646
D A+LLTR+DICR+ KCDTLGLAELGT+CD +SC+I ED+GLS AFTIAHELGHVF++
Sbjct: 383 DTAVLLTRQDICRAHDKCDTLGLAELGTICDPYRSCSISEDSGLSTAFTIAHELGHVFNM 442
Query: 3645 PHDDERKCSTYMPVNKVCKFQSTKFDKTQFQNNFHIMAPTLEYNTHPWSWSPCSAGMLER 3466
PHDD KC K + K + H+MAPTL + T+PW WS CS +
Sbjct: 443 PHDDNNKC----------KEEGVKSPQ-------HVMAPTLNFYTNPWMWSKCSRKYITE 485
Query: 3465 FLENNRGQTQCLFDQPVERRYYEDVFVRDEPGKKYDAHQQCKFVFGPASELCPYMPTCRR 3286
FL+ G+ CL ++P R Y V + PG Y+ ++QC+ +FGP S++CPYM CRR
Sbjct: 486 FLDTGYGE--CLLNEPESRPYPLPVQL---PGILYNVNKQCELIFGPGSQVCPYMMQCRR 540
Query: 3285 LWCATFYGSQMGCRTQHMPWADGTPCDESRSMFCHHGACVRLAPESLTKIDGQWGDWRSW 3106
LWC G GCRTQH PWADGT C+ + C +G CV + + DG WG W +
Sbjct: 541 LWCNNVNGVHKGCRTQHTPWADGTECEPGKH--CKYGFCVPKEMD-VPVTDGSWGSWSPF 597
Query: 3105 GECSRTCGGGVQKGLRDCDSPKPRNGGKYCVGQRERYRSCNTQECPWDTQPYREVQCSEF 2926
G CSRTCGGG++ +R+C+ P+P+NGGKYCVG+R +++SCNT+ C + +R+ QC+ F
Sbjct: 598 GTCSRTCGGGIKTAIRECNRPEPKNGGKYCVGRRMKFKSCNTEPCLKQKRDFRDEQCAHF 657
Query: 2925 NNKDIGIQGVASTNTHWVPKYANVAPNERCKLYCRLSGSAAFYLLRDKVVDGTPCDRNGD 2746
+ K I G+ N WVPKY+ + +RCKL+CR++G+ A+Y LRD+V+DGTPC ++ +
Sbjct: 658 DGKHFNINGLLP-NVRWVPKYSGILMKDRCKLFCRVAGNTAYYQLRDRVIDGTPCGQDTN 716
Query: 2745 DICVAGACMPAGCDHQLHSTLRRDKCGVCGGDDSSCKVVKGTFNEQGTFGYNEVMKIPAG 2566
DICV G C AGCDH L+S RRDKCGVCGGD+SSCK V GTFN +GYN V++IPAG
Sbjct: 717 DICVQGLCRQAGCDHVLNSKARRDKCGVCGGDNSSCKTVAGTFNTV-HYGYNTVVRIPAG 775
Query: 2565 SANIDIRQKGYNNMKEDDNYLSLRAANGEFLLNGHFQVSLARQQIAFQDTVLEYSGSDAI 2386
+ NID+RQ ++ +DDNYL+L ++ GEFLLNG+F V++A+++I + V+EYSGS+
Sbjct: 776 ATNIDVRQHSFSGETDDDNYLALSSSKGEFLLNGNFVVTMAKREIRIGNAVVEYSGSETA 835
Query: 2385 IERINGTGPIRSDIYVHVLSVGS-HPPDISYEYMTAAVPNAVIRPISSALYLWRVTDTWT 2209
+ERIN T I ++ + VLSVG + PD+ Y + N I Y W W
Sbjct: 836 VERINSTDRIEQELLLQVLSVGKLYNPDVRYSF------NIPIEDKPQQFY-WNSHGPWQ 888
Query: 2208 ECDRACRGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRWITEDVSSCS 2029
C + C+G++ +KL+C S D+ C + +P T C DC RW S CS
Sbjct: 889 ACSKPCQGERKRKLVCTRESDQLTVSDQRCDRLPQPGHITEPCGTDCDLRWHVASRSECS 948
Query: 2028 AKCGSGQKRQRVSCVKME--GDRQTPASEHLCDRNSKPSDIASCYIDCSGRKWNYGEWTS 1855
A+CG G + + C K + + C + KPS+ C +C+ W Y WT
Sbjct: 949 AQCGLGYRTLDIYCAKYSRLDGKTEKVDDGFCSSHPKPSNREKCSGECNTGGWRYSAWTE 1008
Query: 1854 CSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWVYGHWSECSR 1675
CS++C G R++ CV+ N +D+S C ++K +R C+ PCP+W G WSEC
Sbjct: 1009 CSKSC-DGGTQRRRAICVNTRNDVLDDSKCTHQEKVTIQR-CSEFPCPQWKSGDWSECLV 1066
Query: 1674 SCDGGVKMRHAQCLDAADRETHTSRCGP---AQTQEHCNEHACTWWQFGVWSDCSAKCGD 1504
+C G K R C DR + C P + + C + C WQ G W CS CG
Sbjct: 1067 TCGKGHKHRQVWCQFGEDR-LNDRMCDPETKPTSMQTCQQPECASWQAGPWVQCSVTCGQ 1125
Query: 1503 GVQYRDANC-TDRHRSVLPEHRC-LKMEKIITKPCHRESC------------------PK 1384
G Q R C + SV+ ++ C T+ C SC +
Sbjct: 1126 GYQLRAVKCIIGTYMSVVDDNDCNAATRPTDTQDCELPSCHPPPAAPETRRSTYSAPRTQ 1185
Query: 1383 YKLGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRN 1204
++ G W+ CS +C G R VSC NG+ D S C T RP + + C++ C W+
Sbjct: 1186 WRFGSWTPCSATCGKGTRMRYVSCRDENGSVADESACATL-PRPVAKEECSVTPCGQWKA 1244
Query: 1203 TDWSACSVSCGIGHRERTTECI-YREQSVDASFCGDTKMPETSQTCHLLPC--------- 1054
DWS+CSV+CG G R C+ Y + +D S C +PET Q C + PC
Sbjct: 1245 LDWSSCSVTCGQGRATRQVMCVNYSDHVIDRSECDQDYIPETDQDCSMSPCPQRTPDSGL 1304
Query: 1053 -------------------------TSWKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIV 949
W+ W CS TC G Q R V C + T
Sbjct: 1305 AQHPFQNEDYRPRSASPSRTHVLGGNQWRTGPWGACSSTCAGGSQRRVVVCQDENGYTAN 1364
Query: 948 DEYFCDRNTRPRLKKTCEKDTCD--------------GPRVLQKLQA------------- 850
D C +P ++ CE C G + +L
Sbjct: 1365 D---CVERIKPDEQRACESGPCPQWAYGNWGECTKLCGGGIRTRLVVCQRSNGERFPDLS 1421
Query: 849 ----DVPPIR-------------WATGPWTACSATCGNGTQRRLLKC-RDHVRDLPDEYC 724
D PP R W+TGPW++CS +CG G ++R + C L +YC
Sbjct: 1422 CEILDKPPDREQCNTHACPHDAAWSTGPWSSCSVSCGRGHKQRNVYCMAKDGSHLESDYC 1481
Query: 723 NHLDKEVSTRNCRLRDCSYWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDC 544
HL K R CR C WK W +C +CG VQQ R+V C + G I ++ +C
Sbjct: 1482 KHLAKPHGHRKCRGGRCPKWKAGAWSQCSVSCGRGVQQ-RHVGC---QIGTHKIARETEC 1537
Query: 543 DVQKRPTSARNCRLEPCPKGEEHIGSWIIGDWSKCSASCGGGWXXXXXXXXXXXCDE--- 373
+ RP S R+C+ CP + +W +W +C+ +CG G +E
Sbjct: 1538 NPYTRPESERDCQGPRCP-----LYTWRAEEWQECTKTCGEGSRYRKVVCVDDNKNEVHG 1592
Query: 372 -----TRKPKMFDKCNEELCPPLTNNSWQISPWTHCSVSCGGGVQRRKIWCEDVLSGRK- 211
+++P + C+ + C + W W+ CSV+CG G ++R + C ++ +G++
Sbjct: 1593 ARCDVSKRPVDRESCSLQPCEYV----WITGEWSECSVTCGKGYKQRLVSCSEIYTGKEN 1648
Query: 210 -----QDDIECSEIKPREQRDCEMPPC 145
Q I C +P C + C
Sbjct: 1649 YEYSYQTTINCPGTQPPSVHPCYLREC 1675
Score = 255 bits (651), Expect = 9e-66
Identities = 173/646 (26%), Positives = 267/646 (40%), Gaps = 76/646 (11%)
Frame = -1
Query: 2214 WTECDRAC-RGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCS--------- 2065
W +C C +G Q + + C+ + D +C +P T+ C +
Sbjct: 1116 WVQCSVTCGQGYQLRAVKCIIGTYMSVVDDNDCNAATRPTD-TQDCELPSCHPPPAAPET 1174
Query: 2064 ---------TRWITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDI 1912
T+W + CSA CG G + + VSC G + A E C +P
Sbjct: 1175 RRSTYSAPRTQWRFGSWTPCSATCGKGTRMRYVSCRDENG---SVADESACATLPRPVAK 1231
Query: 1911 ASCYIDCSGRKWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERE 1732
C + G+ W +W+SCS TCG G+ R+ CV+ S+ +D S C ++ T+++
Sbjct: 1232 EECSVTPCGQ-WKALDWSSCSVTCGQ-GRATRQVMCVNYSDHVIDRSECDQDYIPETDQD 1289
Query: 1731 CNRIPCPR----------------------------------WVYGHWSECSRSCDGGVK 1654
C+ PCP+ W G W CS +C GG +
Sbjct: 1290 CSMSPCPQRTPDSGLAQHPFQNEDYRPRSASPSRTHVLGGNQWRTGPWGACSSTCAGGSQ 1349
Query: 1653 MRHAQCLDAADRETH--TSRCGPAQTQEHCNEHACTWWQFGVWSDCSAKCGDGVQYRDAN 1480
R C D + R P + Q C C W +G W +C+ CG G++ R
Sbjct: 1350 RRVVVCQDENGYTANDCVERIKPDE-QRACESGPCPQWAYGNWGECTKLCGGGIRTRLVV 1408
Query: 1479 CTDRHRSVLPEHRCLKMEKIITKP-----CHRESCPK---YKLGEWSQCSVSCEDGWSSR 1324
C + P+ C +I+ KP C+ +CP + G WS CSVSC G R
Sbjct: 1409 CQRSNGERFPDLSC----EILDKPPDREQCNTHACPHDAAWSTGPWSSCSVSCGRGHKQR 1464
Query: 1323 RVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNTDWSACSVSCGIGHRERTTE 1144
V C++ +G+ ++ C + +P H+ C G CP W+ WS CSVSCG G ++R
Sbjct: 1465 NVYCMAKDGSHLESDYCKHLA-KPHGHRKCRGGRCPKWKAGAWSQCSVSCGRGVQQRHVG 1523
Query: 1143 C-IYREQSVDASFCGDTKMPETSQTCH--LLPCTSWKPSHWSPCSVTCGSGIQTRSVSCT 973
C I + + C PE+ + C P +W+ W C+ TCG G + R V C
Sbjct: 1524 CQIGTHKIARETECNPYTRPESERDCQGPRCPLYTWRAEEWQECTKTCGEGSRYRKVVCV 1583
Query: 972 RGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATC 793
++ + CD + RP +++C C+ W TG W+ CS TC
Sbjct: 1584 DDNKNEVHGAR-CDVSKRPVDRESCSLQPCE--------------YVWITGEWSECSVTC 1628
Query: 792 GNGTQRRLLKCRDHVRDLPD-EYCNHL------DKEVSTRNCRLRDC---SYWKMAEWEE 643
G G ++RL+ C + + EY + S C LR+C + W++ W
Sbjct: 1629 GKGYKQRLVSCSEIYTGKENYEYSYQTTINCPGTQPPSVHPCYLRECPVSATWRVGNWGS 1688
Query: 642 CPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCR 505
C +CG V Q R+V C++ ED + C +P + CR
Sbjct: 1689 CSVSCGVGVMQ-RSVQCLTNEDQPSHL-----CHTDLKPEERKTCR 1728
Score = 195 bits (495), Expect = 1e-47
Identities = 120/410 (29%), Positives = 178/410 (43%), Gaps = 22/410 (5%)
Frame = -1
Query: 2232 WRVTDTWTECDRACRG-QQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRW 2056
WR T W C C G Q + ++C D + + + +C +KP + R C +W
Sbjct: 1332 WR-TGPWGACSSTCAGGSQRRVVVCQDENGYTAN---DCVERIKPDEQ-RACESGPCPQW 1386
Query: 2055 ITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYIDCSGRK- 1879
+ C+ CG G + + V C + G+R S C+ KP D C
Sbjct: 1387 AYGNWGECTKLCGGGIRTRLVVCQRSNGERFPDLS---CEILDKPPDREQCNTHACPHDA 1443
Query: 1878 -WNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWV 1702
W+ G W+SCS +CG G R YC+ ++ C K R+C CP+W
Sbjct: 1444 AWSTGPWSSCSVSCG-RGHKQRNVYCMAKDGSHLESDYCKHLAKPHGHRKCRGGRCPKWK 1502
Query: 1701 YGHWSECSRSCDGGVKMRHAQCLDAADRETHTSRCGP---AQTQEHCNEHACTW--WQFG 1537
G WS+CS SC GV+ RH C + + C P +++ C C W+
Sbjct: 1503 AGAWSQCSVSCGRGVQQRHVGCQIGTHKIARETECNPYTRPESERDCQGPRCPLYTWRAE 1562
Query: 1536 VWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIITKPCHRESCPK------YKL 1375
W +C+ CG+G +YR C D +++ + RC + +P RESC +
Sbjct: 1563 EWQECTKTCGEGSRYRKVVCVDDNKNEVHGARC----DVSKRPVDRESCSLQPCEYVWIT 1618
Query: 1374 GEWSQCSVSCEDGWSSRRVSCVS-----GNGTEVDMSLCGTASDRPASHQTCNLGTCPF- 1213
GEWS+CSV+C G+ R VSC N + +P S C L CP
Sbjct: 1619 GEWSECSVTCGKGYKQRLVSCSEIYTGKENYEYSYQTTINCPGTQPPSVHPCYLRECPVS 1678
Query: 1212 --WRNTDWSACSVSCGIGHRERTTECIYREQSVDASFCGDTKMPETSQTC 1069
WR +W +CSVSCG+G +R+ +C+ E + C PE +TC
Sbjct: 1679 ATWRVGNWGSCSVSCGVGVMQRSVQCLTNEDQ-PSHLCHTDLKPEERKTC 1727
>gi|33624902|ref|NP_891551.1| a disintegrin and metalloproteinase with
thrombospondin motifs 9 isoform 2 preproprotein [Homo
sapiens]
Length = 1629
Score = 988 bits (2554), Expect = 0.0
Identities = 554/1541 (35%), Positives = 771/1541 (49%), Gaps = 110/1541 (7%)
Frame = -1
Query: 4437 CIYRAHVKGVHQHS-IVNLCDSEDGLYGMLALPSGIHTVEPIISGNGTEHDGASRHRQHL 4261
C Y+ +V +H+ +++LC G+ G G + +EP+ S + E D +++ H+
Sbjct: 150 CFYKGYVNTNSEHTAVISLCS---GMLGTFRSHDGDYFIEPLQSMDEQE-DEEEQNKPHI 205
Query: 4260 V-RKFDPMHFKSF--------DHLNSTSVNETETTVATWQDQWE---------------- 4156
+ R+ P S +H N S ++ +T W ++
Sbjct: 206 IYRRSAPQREPSTGRHACDTSEHKNRHSKDKKKTRARKWGERINLAGDVAALNSGLATEA 265
Query: 4155 --------DVIERKARSRRAAN--SWDHYVEVLVVADTKMYEYHGRSLEDYVLTLFSTVA 4006
D K RR S+ +VEVLVVAD +M YHG +L+ Y+LTL S VA
Sbjct: 266 FSAYGNKTDNTREKRTHRRTKRFLSYPRFVEVLVVADNRMVSYHGENLQHYILTLMSIVA 325
Query: 4005 SIYRHQSLRASXXXXXXXXXXXKTENAGPRITQNAQQTLQDFCRWQQYYNDPDDSSVQHH 3826
SIY+ S+ E GP I+ NAQ TL++FC+WQ N P HH
Sbjct: 326 SIYKDPSIGNLINIVIVNLIVIHNEQDGPSISFNAQTTLKNFCQWQHSKNSPGGI---HH 382
Query: 3825 DVAILLTRKDICRSQGKCDTLGLAELGTMCDMQKSCAIIEDNGLSAAFTIAHELGHVFSI 3646
D A+LLTR+DICR+ KCDTLGLAELGT+CD +SC+I ED+GLS AFTIAHELGHVF++
Sbjct: 383 DTAVLLTRQDICRAHDKCDTLGLAELGTICDPYRSCSISEDSGLSTAFTIAHELGHVFNM 442
Query: 3645 PHDDERKCSTYMPVNKVCKFQSTKFDKTQFQNNFHIMAPTLEYNTHPWSWSPCSAGMLER 3466
PHDD KC K + K + H+MAPTL + T+PW WS CS +
Sbjct: 443 PHDDNNKC----------KEEGVKSPQ-------HVMAPTLNFYTNPWMWSKCSRKYITE 485
Query: 3465 FLENNRGQTQCLFDQPVERRYYEDVFVRDEPGKKYDAHQQCKFVFGPASELCPYMPTCRR 3286
FL+ G+ CL ++P R Y V + PG Y+ ++QC+ +FGP S++CPYM CRR
Sbjct: 486 FLDTGYGE--CLLNEPESRPYPLPVQL---PGILYNVNKQCELIFGPGSQVCPYMMQCRR 540
Query: 3285 LWCATFYGSQMGCRTQHMPWADGTPCDESRSMFCHHGACVRLAPESLTKIDGQWGDWRSW 3106
LWC G GCRTQH PWADGT C+ + C +G CV + + DG WG W +
Sbjct: 541 LWCNNVNGVHKGCRTQHTPWADGTECEPGKH--CKYGFCVPKEMD-VPVTDGSWGSWSPF 597
Query: 3105 GECSRTCGGGVQKGLRDCDSPKPRNGGKYCVGQRERYRSCNTQECPWDTQPYREVQCSEF 2926
G CSRTCGGG++ +R+C+ P+P+NGGKYCVG+R +++SCNT+ C + +R+ QC+ F
Sbjct: 598 GTCSRTCGGGIKTAIRECNRPEPKNGGKYCVGRRMKFKSCNTEPCLKQKRDFRDEQCAHF 657
Query: 2925 NNKDIGIQGVASTNTHWVPKYANVAPNERCKLYCRLSGSAAFYLLRDKVVDGTPCDRNGD 2746
+ K I G+ N WVPKY+ + +RCKL+CR++G+ A+Y LRD+V+DGTPC ++ +
Sbjct: 658 DGKHFNINGLLP-NVRWVPKYSGILMKDRCKLFCRVAGNTAYYQLRDRVIDGTPCGQDTN 716
Query: 2745 DICVAGACMPAGCDHQLHSTLRRDKCGVCGGDDSSCKVVKGTFNEQGTFGYNEVMKIPAG 2566
DICV G C AGCDH L+S RRDKCGVCGGD+SSCK V GTFN +GYN V++IPAG
Sbjct: 717 DICVQGLCRQAGCDHVLNSKARRDKCGVCGGDNSSCKTVAGTFNTV-HYGYNTVVRIPAG 775
Query: 2565 SANIDIRQKGYNNMKEDDNYLSLRAANGEFLLNGHFQVSLARQQIAFQDTVLEYSGSDAI 2386
+ NID+RQ ++ +DDNYL+L ++ GEFLLNG+F V++A+++I + V+EYSGS+
Sbjct: 776 ATNIDVRQHSFSGETDDDNYLALSSSKGEFLLNGNFVVTMAKREIRIGNAVVEYSGSETA 835
Query: 2385 IERINGTGPIRSDIYVHVLSVGS-HPPDISYEYMTAAVPNAVIRPISSALYLWRVTDTWT 2209
+ERIN T I ++ + VLSVG + PD+ Y + N I Y W W
Sbjct: 836 VERINSTDRIEQELLLQVLSVGKLYNPDVRYSF------NIPIEDKPQQFY-WNSHGPWQ 888
Query: 2208 ECDRACRGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRWITEDVSSCS 2029
C + C+G++ +KL+C S D+ C + +P T C DC RW S CS
Sbjct: 889 ACSKPCQGERKRKLVCTRESDQLTVSDQRCDRLPQPGHITEPCGTDCDLRWHVASRSECS 948
Query: 2028 AKCGSGQKRQRVSCVKME--GDRQTPASEHLCDRNSKPSDIASCYIDCSGRKWNYGEWTS 1855
A+CG G + + C K + + C + KPS+ C +C+ W Y WT
Sbjct: 949 AQCGLGYRTLDIYCAKYSRLDGKTEKVDDGFCSSHPKPSNREKCSGECNTGGWRYSAWTE 1008
Query: 1854 CSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWVYGHWSECSR 1675
CS++C G R++ CV+ N +D+S C ++K +R C+ PCP+W G WSEC
Sbjct: 1009 CSKSC-DGGTQRRRAICVNTRNDVLDDSKCTHQEKVTIQR-CSEFPCPQWKSGDWSECLV 1066
Query: 1674 SCDGGVKMRHAQCLDAADRETHTSRCGP---AQTQEHCNEHACTWWQFGVWSDCSAKCGD 1504
+C G K R C DR + C P + + C + C WQ G W CS CG
Sbjct: 1067 TCGKGHKHRQVWCQFGEDR-LNDRMCDPETKPTSMQTCQQPECASWQAGPWGQCSVTCGQ 1125
Query: 1503 GVQYRDANC-TDRHRSVLPEHRC-LKMEKIITKPCHRESC------------------PK 1384
G Q R C + SV+ ++ C T+ C SC +
Sbjct: 1126 GYQLRAVKCIIGTYMSVVDDNDCNAATRPTDTQDCELPSCHPPPAAPETRRSTYSAPRTQ 1185
Query: 1383 YKLGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRN 1204
++ G W+ CS +C G R VSC NG+ D S C T RP + + C++ C W+
Sbjct: 1186 WRFGSWTPCSATCGKGTRMRYVSCRDENGSVADESACATL-PRPVAKEECSVTPCGQWKA 1244
Query: 1203 TDWSACSVSCGIGHRERTTECI-YREQSVDASFCGDTKMPETSQTCHLLPC--------- 1054
DWS+CSV+CG G R C+ Y + +D S C +PET Q C + PC
Sbjct: 1245 LDWSSCSVTCGQGRATRQVMCVNYSDHVIDRSECDQDYIPETDQDCSMSPCPQRTPDSGL 1304
Query: 1053 -------------------------TSWKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIV 949
W+ W CS TC G Q R V C + T
Sbjct: 1305 AQHPFQNEDYRPRSASPSRTHVLGGNQWRTGPWGACSSTCAGGSQRRVVVCQDENGYTAN 1364
Query: 948 DEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATCGNGTQRRL 769
D C +P ++ CE C +WA G W C+ CG G + RL
Sbjct: 1365 D---CVERIKPDEQRACESGPCP---------------QWAYGNWGECTKLCGGGIRTRL 1406
Query: 768 LKC-RDHVRDLPDEYCNHLDKEVSTRNCRLRDCSY---WKMAEWEECPATCGTHVQQSRN 601
+ C R + PD C LDK C C + W W C +CG +Q RN
Sbjct: 1407 VVCQRSNGERFPDLSCEILDKPPDREQCNTHACPHDAAWSTGPWSSCSVSCGRGHKQ-RN 1465
Query: 600 VTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPKGEEHIGSWIIGDWSKCSASCGG 421
V C+ A+DG L+ C +P R CR CPK W G WS+CS SCG
Sbjct: 1466 VYCM-AKDGSH--LESDYCKHLAKPHGHRKCRGGRCPK-------WKAGAWSQCSVSCGR 1515
Query: 420 GWXXXXXXXXXXXCDETR--------KPKMFDKCNEELCPPLTNNSWQISPWTHCSVSCG 265
G R +P+ C CP T W+ W C+ +CG
Sbjct: 1516 GVQQRHVGCQIGTHKIARETECNPYTRPESERDCQGPRCPLYT---WRAEEWQECTKTCG 1572
Query: 264 GGVQRRKIWCEDVLSGRKQDDIECSEIK-PREQRDCEMPPC 145
G + RK+ C D + + C K P ++ C + PC
Sbjct: 1573 EGSRYRKVVCVDD-NKNEVHGARCDVSKRPVDRESCSLQPC 1612
Score = 254 bits (649), Expect = 1e-65
Identities = 160/595 (26%), Positives = 245/595 (40%), Gaps = 62/595 (10%)
Frame = -1
Query: 2232 WRVTDTWTECDRAC-RGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRW 2056
W+ D W+EC C +G + +++ C + +DR C KP +C++ W
Sbjct: 1056 WKSGD-WSECLVTCGKGHKHRQVWC--QFGEDRLNDRMCDPETKPTSMQTCQQPECAS-W 1111
Query: 2055 ITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYI------- 1897
CS CG G + + V C+ G + ++ C+ ++P+D C +
Sbjct: 1112 QAGPWGQCSVTCGQGYQLRAVKCII--GTYMSVVDDNDCNAATRPTDTQDCELPSCHPPP 1169
Query: 1896 ----------DCSGRKWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKE 1747
+W +G WT CS TCG +M S C D++ DES C +
Sbjct: 1170 AAPETRRSTYSAPRTQWRFGSWTPCSATCGKGTRMRYVS-CRDENGSVADESACATLPRP 1228
Query: 1746 ATERECNRIPCPRWVYGHWSECSRSCDGGVKMRHAQCLDAADRETHTSRCGP---AQTQE 1576
+ EC+ PC +W WS CS +C G R C++ +D S C +T +
Sbjct: 1229 VAKEECSVTPCGQWKALDWSSCSVTCGQGRATRQVMCVNYSDHVIDRSECDQDYIPETDQ 1288
Query: 1575 HCNEHAC----------------------------------TWWQFGVWSDCSAKCGDGV 1498
C+ C W+ G W CS+ C G
Sbjct: 1289 DCSMSPCPQRTPDSGLAQHPFQNEDYRPRSASPSRTHVLGGNQWRTGPWGACSSTCAGGS 1348
Query: 1497 QYRDANCTDRHRSVLPEHRCL-KMEKIITKPCHRESCPKYKLGEWSQCSVSCEDGWSSRR 1321
Q R C D + + C+ +++ + C CP++ G W +C+ C G +R
Sbjct: 1349 QRRVVVCQDENGYTAND--CVERIKPDEQRACESGPCPQWAYGNWGECTKLCGGGIRTRL 1406
Query: 1320 VSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPF---WRNTDWSACSVSCGIGHRERT 1150
V C NG C D+P + CN CP W WS+CSVSCG GH++R
Sbjct: 1407 VVCQRSNGERFPDLSCEIL-DKPPDREQCNTHACPHDAAWSTGPWSSCSVSCGRGHKQRN 1465
Query: 1149 TECIYREQS-VDASFCGDTKMPETSQTCHLLPCTSWKPSHWSPCSVTCGSGIQTRSVSCT 973
C+ ++ S +++ +C P + C C WK WS CSV+CG G+Q R V C
Sbjct: 1466 VYCMAKDGSHLESDYCKHLAKPHGHRKCRGGRCPKWKAGAWSQCSVSCGRGVQQRHVGCQ 1525
Query: 972 RGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATC 793
G+ I E C+ TRP ++ C+ GPR P W W C+ TC
Sbjct: 1526 IGTH-KIARETECNPYTRPESERDCQ-----GPRC--------PLYTWRAEEWQECTKTC 1571
Query: 792 GNGTQRRLLKC-RDHVRDLPDEYCNHLDKEVSTRNCRLRDCSY-WKMAEWEECPA 634
G G++ R + C D+ ++ C+ + V +C L+ C Y W EW E P+
Sbjct: 1572 GEGSRYRKVVCVDDNKNEVHGARCDVSKRPVDRESCSLQPCEYVWITGEWSEVPS 1626
>gi|29611732|sp|P59511|AT20_MOUSE ADAMTS-20 precursor (A disintegrin
and metalloproteinase with thrombospondin motifs 20)
(ADAM-TS 20) (ADAM-TS20)
gi|28804249|emb|CAD54808.3| metalloprotease-disintegrin protease [Mus
musculus]
Length = 1906
Score = 985 bits (2547), Expect = 0.0
Identities = 577/1600 (36%), Positives = 794/1600 (49%), Gaps = 156/1600 (9%)
Frame = -1
Query: 4464 GGMSRTDPD---CIYRAHVKGVHQHSIV-NLCDSEDGLYGMLALPSGIHTVEPIISGNGT 4297
GG S PD C YR V H+ V +LC GL G G + +EP++ +G+
Sbjct: 117 GGRSTESPDLRHCFYRGQVNAREDHTAVFSLCG---GLMGTFKANDGEYFLEPVLRADGS 173
Query: 4296 EHDGASRHRQHLVRKFDPMHFKSFDHLNS---TSVNETETTVATWQ---------DQWED 4153
HD ++ HL+ + + + SF + S N+ E T Q D E+
Sbjct: 174 AHDD-DHNKPHLIYRQE-LKRNSFARSHKPCEVSENQMEKTALPSQSSRNTTGDVDIEEE 231
Query: 4152 VIERKARSRRAANS-------WDHYVEVLVVADTKMYEYHGRSLEDYVLTLFSTVASIYR 3994
+ R R +S + YVEV+V AD KM +HG++L+ YVLTL S VA+IY+
Sbjct: 232 AVFRLEGERSQLHSRNKRFLSYPRYVEVMVTADAKMVHHHGQNLQHYVLTLMSIVAAIYK 291
Query: 3993 HQSLRASXXXXXXXXXXXKTENAGPRITQNAQQTLQDFCRWQQYYNDPDDSSVQHHDVAI 3814
S+ +E GP I+ NA TL++FC WQQ N PDD+ HHD A+
Sbjct: 292 DSSIGNLINIVIVKLVVIHSEQEGPVISFNAATTLRNFCLWQQSQNVPDDAHPSHHDTAV 351
Query: 3813 LLTRKDICRSQGKCDTLGLAELGTMCDMQKSCAIIEDNGLSAAFTIAHELGHVFSIPHDD 3634
L+TR+DIC ++ KCDTLGLAELGT+CD +SC+I E+NGLSAAFTIAHELGHVF++PHDD
Sbjct: 352 LITREDICGAKEKCDTLGLAELGTLCDPSRSCSISEENGLSAAFTIAHELGHVFNVPHDD 411
Query: 3633 ERKCSTYMPVNKVCKFQSTKFDKTQFQNNFHIMAPTLEYNTHPWSWSPCSAGMLERFLEN 3454
KC + ++ +H+MAPTL Y+T PW+WS CS + FL+
Sbjct: 412 SFKCK-----------------EAGIKHQYHVMAPTLNYHTSPWTWSACSQKHITEFLDT 454
Query: 3453 NRGQTQCLFDQPVERRYYEDVFVRDEPGKKYDAHQQCKFVFGPASELCPYMPTCRRLWCA 3274
G +CL D+P R Y PG YD ++QC+ +FGP S++CPY+ CRRLWC
Sbjct: 455 GHG--ECLLDKPNGRTY---DLSPQLPGSVYDGNRQCELMFGPGSQVCPYLKHCRRLWCT 509
Query: 3273 TFYGSQMGCRTQHMPWADGTPCDESRSMFCHHGACVRLAPESLTKIDGQWGDWRSWGECS 3094
+ G GCRTQHMP ADGT C M CH G CV E+ +DG+WG W + CS
Sbjct: 510 SAEGVHKGCRTQHMPLADGTSC--GPGMHCHRGLCVTRDMET-RPVDGEWGPWGPYSSCS 566
Query: 3093 RTCGGGVQKGLRDCDSPKPRNGGKYCVGQRERYRSCNTQECPWDTQPYREVQCSEFNNKD 2914
RTCGGG++ R CD P+PRNGG+YCVG+R ++RSCNT CP + +RE QCS+F+ K
Sbjct: 567 RTCGGGIKSTARLCDRPEPRNGGRYCVGRRMKFRSCNTDSCPKGKRDFREKQCSDFDGKH 626
Query: 2913 IGIQGVASTNTHWVPKYANVAPNERCKLYCRLSGSAAFYLLRDKVVDGTPCDRNGDDICV 2734
I G+ N W+PKY+ +A +RCKLYCR++G+ +FY L+D+V DGTPC +DICV
Sbjct: 627 FDINGL-PPNVRWLPKYSGIAVKDRCKLYCRVAGTTSFYQLKDRVADGTPCGTETNDICV 685
Query: 2733 AGACMPAGCDHQLHSTLRRDKCGVCGGDDSSCKVVKGTFNEQGTFGYNEVMKIPAGSANI 2554
G C AGCDH L+S +RDKCGVCGGD+SSC+ + G FN +GYN V+KIPAG+ NI
Sbjct: 686 QGLCRQAGCDHVLNSKAKRDKCGVCGGDNSSCQTLAGVFN-SAHYGYNVVVKIPAGATNI 744
Query: 2553 DIRQKGYNNMKEDDNYLSLRAANGEFLLNGHFQVSLARQQIAFQDTVLEYSGSDAIIERI 2374
+I Q Y+ EDDNYL+L G FLLNG+F VS+A+++I Q V EYSGS+ IERI
Sbjct: 745 EILQHSYSGRPEDDNYLALSDTQGNFLLNGNFVVSMAKKEINIQGAVFEYSGSNNSIERI 804
Query: 2373 NGTGPIRSDIYVHVLSVGS-HPPDISYEYMTAAVPNAVIRPISSALYLWRVTDTWTECDR 2197
N T + +++ + VL VG+ + PD+ Y + N I S+ L+ W W +C +
Sbjct: 805 NSTDRLEAELVLQVLCVGNLYNPDVRYSF------NIPIEERSN-LFSWDPYGPWQDCTK 857
Query: 2196 ACRGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRWITEDVSSCSAKCG 2017
C+G +K+ C+ S H D NC ++ P T CN+DC RW S CS++CG
Sbjct: 858 MCQGLHRRKIACVRKSDHAVVSDHNCGHLPMPLFVTEKCNMDCELRWHIIGKSDCSSQCG 917
Query: 2016 SGQKRQRVSCVK--MEGDRQTPASEHLCDRNSKPSDIASCYIDCSGRKWNYGEWTSCSET 1843
G + V C+K + + P + C KP C+ C +W+Y EW+ CS +
Sbjct: 918 QGYRTLDVHCMKYSVHKGQAVPVGDQYCGDQLKPPSREPCHGSCVLTRWHYSEWSQCSRS 977
Query: 1842 CGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWVYGHWSECSRSCDG 1663
CG K R+SYCV+ R+ ES C RE CN PCP W WSEC +C
Sbjct: 978 CGGGDKT-RESYCVNGFGHRLAESEC-RELPRVVLENCNEFPCPSWATSEWSECPVTCGK 1035
Query: 1662 GVKMRHAQCLDAAD--RETHTSRCGPAQTQEHCNEHACTWWQFGVWSDCSAKCGDGVQYR 1489
G+K R C + D R+ + ++ C AC W G W C+A CG G Q R
Sbjct: 1036 GMKQRQVWCQLSEDPMRDGFCNASTKPESLRPCELRACASWHVGPWGSCTATCGHGYQMR 1095
Query: 1488 DANC-TDRHRSVLPEHRCLKMEKIITKPCHRESC------------------------PK 1384
C ++ ++L + C + ++P R+ C +
Sbjct: 1096 AVKCISEIFGTMLDDRECPQ----ASRPSDRQDCILAPCLAIPEVGATSLPAIPLGRAAQ 1151
Query: 1383 YKLGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRN 1204
++ G W+ CSVSC G +R VSC + D S C RPA+ C C W+
Sbjct: 1152 WRHGSWTPCSVSCGRGSQARYVSCRDAHDEVADESNCAHL-PRPAAVSLC-FSPCGEWQA 1209
Query: 1203 TDWSACSVSCGIGHRERTTECIYREQSVDASFCGDTKMPETSQTCHLLPC---------T 1051
DWS CS SCG G R C+ Q VD S+C P T Q C L C +
Sbjct: 1210 GDWSPCSASCGHGKTTRRVLCVNYHQLVDESYCDPEGRPVTEQECSLAACPPSYSRAPSS 1269
Query: 1050 SWKPSH---------------------------------WSPCSVTCGSGIQTRSVSCTR 970
S +PSH W CS +C G+Q R+V C +
Sbjct: 1270 SEQPSHVPSRNVPLTHKPGENQDQGAQLSIRGNQWRTGPWGACSRSCAGGLQHRAVVC-Q 1328
Query: 969 GSEGTIVDEYFCDRNTRPRLKKTCEK---------------DTCDG-------------- 877
+G CD +++P + C TC G
Sbjct: 1329 DEDGRSATS--CDGSSKPPESRHCGSGPCPHWNYGDWGECTQTCGGGVKSRFVICQFPNG 1386
Query: 876 -------------PRVLQ-KLQADVPPIRWATGPWTACSATCGNGTQRRLLKCRDHV-RD 742
P ++Q L A + W GPW +CSA+CG G + R + C D R
Sbjct: 1387 QMTQEHSCELPKPPSMMQCHLHACPEDVSWYRGPWKSCSASCGKGVKYREVLCIDQFQRK 1446
Query: 741 LPDEYCNHLDKEVSTRNCRLRDCSYWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTI 562
L ++YC+HL K + + CR C WK +W+EC TCG+ VQQ R V C G +
Sbjct: 1447 LEEKYCSHLHKPRTHKACRSGRCPSWKANKWKECSVTCGSGVQQ-REVYCRLRGTG--RV 1503
Query: 561 LKDVDCDVQKRPTSARNCRLEPCPKGEEHIGSWIIGDWSKCSASCGGGWXXXXXXXXXXX 382
+D+ CD RP R C + C + + W GDW CS SC
Sbjct: 1504 SEDM-CDPSTRPQGQRQCWRQDCMRYQ-----WTTGDWLDCSTSC-------------KK 1544
Query: 381 CDETRKPKMFD----KCNEELCPPLT---------NNSWQISPWT----HCSVSCGGGVQ 253
+ R K + + NE LC PLT N + S T C+ +CG
Sbjct: 1545 KETYRLVKCVNEQNVQANESLCDPLTKPLSIKKCRNPHCKYSVVTGDSSQCAGNCGFTSP 1604
Query: 252 RRKIWCEDVLSGRKQDDIECSEIKPREQRDCEMPPCRSHY 133
++ +C + S +K +++P +C + P Y
Sbjct: 1605 QKITYCTKIQSSKKH---TFHQLRPVVYGECPVIPSPQAY 1641
Score = 262 bits (670), Expect = 5e-68
Identities = 190/684 (27%), Positives = 270/684 (38%), Gaps = 82/684 (11%)
Frame = -1
Query: 2223 TDTWTECDRAC-RGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRWITE 2047
T W+EC C +G + +++ C + D C KP ++ R C + W
Sbjct: 1023 TSEWSECPVTCGKGMKQRQVWC--QLSEDPMRDGFCNASTKP-ESLRPCELRACASWHVG 1079
Query: 2046 DVSSCSAKCGSGQKRQRVSCVK-----MEGDRQTPASEHLCDRNSKPSDIASCYI-DCS- 1888
SC+A CG G + + V C+ M DR+ C + S+PSD C + C
Sbjct: 1080 PWGSCTATCGHGYQMRAVKCISEIFGTMLDDRE-------CPQASRPSDRQDCILAPCLA 1132
Query: 1887 --------------GR--KWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGRE 1756
GR +W +G WT CS +CG G R C D + DES C
Sbjct: 1133 IPEVGATSLPAIPLGRAAQWRHGSWTPCSVSCG-RGSQARYVSCRDAHDEVADESNCAHL 1191
Query: 1755 QKEATERECNRIPCPRWVYGHWSECSRSCDGGVKMRHAQCLDAADR--ETHTSRCGPAQT 1582
+ A C PC W G WS CS SC G R C++ E++ G T
Sbjct: 1192 PRPAAVSLCFS-PCGEWQAGDWSPCSASCGHGKTTRRVLCVNYHQLVDESYCDPEGRPVT 1250
Query: 1581 QEHCNEHAC------------------------------------------TWWQFGVWS 1528
++ C+ AC W+ G W
Sbjct: 1251 EQECSLAACPPSYSRAPSSSEQPSHVPSRNVPLTHKPGENQDQGAQLSIRGNQWRTGPWG 1310
Query: 1527 DCSAKCGDGVQYRDANCTDRH-RSVLPEHRCLKMEKIITKPCHRESCPKYKLGEWSQCSV 1351
CS C G+Q+R C D RS K + ++ C CP + G+W +C+
Sbjct: 1311 ACSRSCAGGLQHRAVVCQDEDGRSATSCDGSSKPPE--SRHCGSGPCPHWNYGDWGECTQ 1368
Query: 1350 SCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCP---FWRNTDWSACSV 1180
+C G SR V C NG C +P S C+L CP W W +CS
Sbjct: 1369 TCGGGVKSRFVICQFPNGQMTQEHSCELP--KPPSMMQCHLHACPEDVSWYRGPWKSCSA 1426
Query: 1179 SCGIGHRERTTECIYR-EQSVDASFCGDTKMPETSQTCHLLPCTSWKPSHWSPCSVTCGS 1003
SCG G + R CI + ++ ++ +C P T + C C SWK + W CSVTCGS
Sbjct: 1427 SCGKGVKYREVLCIDQFQRKLEEKYCSHLHKPRTHKACRSGRCPSWKANKWKECSVTCGS 1486
Query: 1002 GIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWAT 823
G+Q R V C G V E CD +TRP+ ++ C + C +W T
Sbjct: 1487 GVQQREVYCRLRGTGR-VSEDMCDPSTRPQGQRQCWRQDC-------------MRYQWTT 1532
Query: 822 GPWTACSATCGNGTQRRLLKCRDHVRDLPDE-YCNHLDKEVSTRNCRLRDCSYWKMA-EW 649
G W CS +C RL+KC + +E C+ L K +S + CR C Y + +
Sbjct: 1533 GDWLDCSTSCKKKETYRLVKCVNEQNVQANESLCDPLTKPLSIKKCRNPHCKYSVVTGDS 1592
Query: 648 EECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPKGEE--- 478
+C CG Q + C + + Q RP C + P P+ +
Sbjct: 1593 SQCAGNCGFTSPQ-KITYCTKIQSSKKHTFH------QLRPVVYGECPVIPSPQAYKCDL 1645
Query: 477 ----HIGSWIIGDWSKCSASCGGG 418
H+ +W +G WSKCS +CG G
Sbjct: 1646 RSCLHVATWKVGKWSKCSVTCGIG 1669
Score = 257 bits (656), Expect = 2e-66
Identities = 179/669 (26%), Positives = 259/669 (37%), Gaps = 86/669 (12%)
Frame = -1
Query: 1872 YGEWTSCSETCGSNGKMHRKSYCVDDSNRRV-DESLCGREQKEATERECNRIPCP-RWVY 1699
YG W C++ C G RK CV S+ V + CG E + C RW
Sbjct: 849 YGPWQDCTKMC--QGLHRRKIACVRKSDHAVVSDHNCGHLPMPLFVTEKCNMDCELRWHI 906
Query: 1698 GHWSECSRSCDGGVKMRHAQCLDAADRETHTSRCGPAQTQEHCNEH-------------A 1558
S+CS C G + C+ + H + P Q +C +
Sbjct: 907 IGKSDCSSQCGQGYRTLDVHCMKYS---VHKGQAVPVGDQ-YCGDQLKPPSREPCHGSCV 962
Query: 1557 CTWWQFGVWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIITKPCHRESCPKYK 1378
T W + WS CS CG G + R++ C + L E C ++ +++ + C+ CP +
Sbjct: 963 LTRWHYSEWSQCSRSCGGGDKTRESYCVNGFGHRLAESECRELPRVVLENCNEFPCPSWA 1022
Query: 1377 LGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNTD 1198
EWS+C V+C G R+V C D C AS +P S + C L C W
Sbjct: 1023 TSEWSECPVTCGKGMKQRQVWCQLSEDPMRD-GFCN-ASTKPESLRPCELRACASWHVGP 1080
Query: 1197 WSACSVSCGIGHRERTTECIYR--EQSVDASFCGDTKMPETSQTCHLLPCTS-------- 1048
W +C+ +CG G++ R +CI +D C P Q C L PC +
Sbjct: 1081 WGSCTATCGHGYQMRAVKCISEIFGTMLDDRECPQASRPSDRQDCILAPCLAIPEVGATS 1140
Query: 1047 -----------WKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKT 901
W+ W+PCSV+CG G Q R VSC R + + DE C RP
Sbjct: 1141 LPAIPLGRAAQWRHGSWTPCSVSCGRGSQARYVSC-RDAHDEVADESNCAHLPRPAAVSL 1199
Query: 900 CEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATCGNGTQRRLLKCRDHVRDLPDEYCN 721
C P W G W+ CSA+CG+G R + C ++ + + + YC+
Sbjct: 1200 CFS----------------PCGEWQAGDWSPCSASCGHGKTTRRVLCVNYHQLVDESYCD 1243
Query: 720 HLDKEVSTRNCRLRDC------------------------------------------SY 667
+ V+ + C L C +
Sbjct: 1244 PEGRPVTEQECSLAACPPSYSRAPSSSEQPSHVPSRNVPLTHKPGENQDQGAQLSIRGNQ 1303
Query: 666 WKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPK 487
W+ W C +C +Q R V C ++ GR+ CD +P +R+C PCP
Sbjct: 1304 WRTGPWGACSRSCAGGLQH-RAVVC--QDEDGRSA---TSCDGSSKPPESRHCGSGPCPH 1357
Query: 486 GEEHIGSWIIGDWSKCSASCGGGWXXXXXXXXXXXCDETR-------KPKMFDKCNEELC 328
W GDW +C+ +CGGG T+ KP +C+ C
Sbjct: 1358 -------WNYGDWGECTQTCGGGVKSRFVICQFPNGQMTQEHSCELPKPPSMMQCHLHAC 1410
Query: 327 PPLTNNSWQISPWTHCSVSCGGGVQRRKIWCEDVLSGRKQDDIECSEI-KPREQRDCEMP 151
P + SW PW CS SCG GV+ R++ C D RK ++ CS + KPR + C
Sbjct: 1411 PE--DVSWYRGPWKSCSASCGKGVKYREVLCIDQFQ-RKLEEKYCSHLHKPRTHKACRSG 1467
Query: 150 PCRSHYHNK 124
C S NK
Sbjct: 1468 RCPSWKANK 1476
Score = 219 bits (559), Expect = 4e-55
Identities = 164/642 (25%), Positives = 237/642 (36%), Gaps = 122/642 (19%)
Frame = -1
Query: 2232 WRVTDTWTECDRAC-RGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDC---- 2068
W V W C C G Q + + C+ DR C +P C
Sbjct: 1076 WHV-GPWGSCTATCGHGYQMRAVKCISEIFGTMLDDRECPQASRPSDRQDCILAPCLAIP 1134
Query: 2067 --------------STRWITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRN 1930
+ +W + CS CG G + + VSC + A E C
Sbjct: 1135 EVGATSLPAIPLGRAAQWRHGSWTPCSVSCGRGSQARYVSCRDAHDE---VADESNCAHL 1191
Query: 1929 SKPSDIASCYIDCSGRKWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQK 1750
+P+ ++ C+ C +W G+W+ CS +CG +GK R+ CV+ ++ VDES C E +
Sbjct: 1192 PRPAAVSLCFSPCG--EWQAGDWSPCSASCG-HGKTTRRVLCVN-YHQLVDESYCDPEGR 1247
Query: 1749 EATERECNRIPCP------------------------------------------RWVYG 1696
TE+EC+ CP +W G
Sbjct: 1248 PVTEQECSLAACPPSYSRAPSSSEQPSHVPSRNVPLTHKPGENQDQGAQLSIRGNQWRTG 1307
Query: 1695 HWSECSRSCDGGVKMRHAQCLDAADRETHTSRCGPAQTQE--HCNEHACTWWQFGVWSDC 1522
W CSRSC GG++ R C D D + TS G ++ E HC C W +G W +C
Sbjct: 1308 PWGACSRSCAGGLQHRAVVCQDE-DGRSATSCDGSSKPPESRHCGSGPCPHWNYGDWGEC 1366
Query: 1521 SAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIITKPCHRESCPK---YKLGEWSQCSV 1351
+ CG GV+ R C + + EH C + CH +CP+ + G W CS
Sbjct: 1367 TQTCGGGVKSRFVICQFPNGQMTQEHSCELPKPPSMMQCHLHACPEDVSWYRGPWKSCSA 1426
Query: 1350 SCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNTDWSACSVSCG 1171
SC G R V C+ +++ C +P +H+ C G CP W+ W CSV+CG
Sbjct: 1427 SCGKGVKYREVLCIDQFQRKLEEKYCSHLH-KPRTHKACRSGRCPSWKANKWKECSVTCG 1485
Query: 1170 IGHRERTTECIYREQS-VDASFCGDTKMPETSQTCHLLPCT--SWKPSHWSPCSVTCGSG 1000
G ++R C R V C + P+ + C C W W CS +C
Sbjct: 1486 SGVQQREVYCRLRGTGRVSEDMCDPSTRPQGQRQCWRQDCMRYQWTTGDWLDCSTSCKKK 1545
Query: 999 IQTRSVSCTRGSEGTIVDEYFCDRNTRP-RLKK-----------TCEKDTCDG------P 874
R V C + +E CD T+P +KK T + C G P
Sbjct: 1546 ETYRLVKCVN-EQNVQANESLCDPLTKPLSIKKCRNPHCKYSVVTGDSSQCAGNCGFTSP 1604
Query: 873 RVLQ---KLQA---------------DVPPI-----------------RWATGPWTACSA 799
+ + K+Q+ + P I W G W+ CS
Sbjct: 1605 QKITYCTKIQSSKKHTFHQLRPVVYGECPVIPSPQAYKCDLRSCLHVATWKVGKWSKCSV 1664
Query: 798 TCGNGTQRRLLKCRDHVRDLPDEYCNHLDKEVSTRNCRLRDC 673
TCG G R + CR P + C K + + C DC
Sbjct: 1665 TCGIGIMERRVACRTE-NGWPSDLCLKRLKPDAQKKCYANDC 1705
Score = 186 bits (472), Expect = 5e-45
Identities = 129/428 (30%), Positives = 183/428 (42%), Gaps = 25/428 (5%)
Frame = -1
Query: 2061 RWITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYIDCSGR 1882
+W T +CS C G + + V C +G T CD +SKP + C SG
Sbjct: 1303 QWRTGPWGACSRSCAGGLQHRAVVCQDEDGRSATS-----CDGSSKPPESRHCG---SGP 1354
Query: 1881 --KWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPR 1708
WNYG+W C++TCG G R C + + E C K + +C+ CP
Sbjct: 1355 CPHWNYGDWGECTQTCGG-GVKSRFVICQFPNGQMTQEHSC-ELPKPPSMMQCHLHACPE 1412
Query: 1707 ---WVYGHWSECSRSCDGGVKMRHAQCLDAADRETHTSRCG---PAQTQEHCNEHACTWW 1546
W G W CS SC GVK R C+D R+ C +T + C C W
Sbjct: 1413 DVSWYRGPWKSCSASCGKGVKYREVLCIDQFQRKLEEKYCSHLHKPRTHKACRSGRCPSW 1472
Query: 1545 QFGVWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKII-TKPCHRESCPKYK--L 1375
+ W +CS CG GVQ R+ C R + E C + + C R+ C +Y+
Sbjct: 1473 KANKWKECSVTCGSGVQQREVYCRLRGTGRVSEDMCDPSTRPQGQRQCWRQDCMRYQWTT 1532
Query: 1374 GEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNT-D 1198
G+W CS SC+ + R V CV+ + + SLC + +P S + C C + T D
Sbjct: 1533 GDWLDCSTSCKKKETYRLVKCVNEQNVQANESLCDPLT-KPLSIKKCRNPHCKYSVVTGD 1591
Query: 1197 WSACSVSCGIGHRERTTECIYREQSVDASF----------CGDTKMPETSQTCHLLPC-- 1054
S C+ +CG ++ T C + S +F C P+ + C L C
Sbjct: 1592 SSQCAGNCGFTSPQKITYCTKIQSSKKHTFHQLRPVVYGECPVIPSPQAYK-CDLRSCLH 1650
Query: 1053 -TSWKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDG 877
+WK WS CSVTCG GI R V+C R G D C + +P +K C + C
Sbjct: 1651 VATWKVGKWSKCSVTCGIGIMERRVAC-RTENGWPSD--LCLKRLKPDAQKKCYANDCKL 1707
Query: 876 PRVLQKLQ 853
++LQ
Sbjct: 1708 LTTCKELQ 1715
Score = 66.2 bits (160), Expect = 7e-09
Identities = 45/185 (24%), Positives = 78/185 (41%), Gaps = 10/185 (5%)
Frame = -1
Query: 2238 YLWRVTDTWTECDRACRGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTR 2059
Y W D W +C +C+ +++ +L+ + Q+++ C + KP + N C
Sbjct: 1528 YQWTTGD-WLDCSTSCKKKETYRLVKCVNEQNVQANESLCDPLTKPLSIKKCRNPHCKYS 1586
Query: 2058 WITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQ------TPASEHLCDRNSKPS----DIA 1909
+T D S C+ CG ++ C K++ ++ P C P D+
Sbjct: 1587 VVTGDSSQCAGNCGFTSPQKITYCTKIQSSKKHTFHQLRPVVYGECPVIPSPQAYKCDLR 1646
Query: 1908 SCYIDCSGRKWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATEREC 1729
SC + W G+W+ CS TCG G M R+ C ++ D LC + K +++C
Sbjct: 1647 SCLHVAT---WKVGKWSKCSVTCGI-GIMERRVACRTENGWPSD--LCLKRLKPDAQKKC 1700
Query: 1728 NRIPC 1714
C
Sbjct: 1701 YANDC 1705
>gi|31982227|ref|NP_803180.2| a disintegrin-like and metalloprotease
(reprolysin type) with thrombospondin type 1 motif, 20; a
disintegrin-like and metalloprotease with thrombospondin
type 1 motifs 20; belted [Mus musculus]
gi|29500513|gb|AAO74895.1| ADAMTS20 B long isoform [Mus musculus]
Length = 1906
Score = 982 bits (2538), Expect = 0.0
Identities = 576/1600 (36%), Positives = 793/1600 (49%), Gaps = 156/1600 (9%)
Frame = -1
Query: 4464 GGMSRTDPD---CIYRAHVKGVHQHSIV-NLCDSEDGLYGMLALPSGIHTVEPIISGNGT 4297
GG S PD C YR V H+ V +LC GL G G + +EP++ +G+
Sbjct: 117 GGRSTESPDLRHCFYRGQVNAREDHTAVFSLCG---GLMGTFKANDGEYFLEPVLRADGS 173
Query: 4296 EHDGASRHRQHLVRKFDPMHFKSFDHLNS---TSVNETETTVATWQ---------DQWED 4153
HD ++ HL+ + + + SF + S N+ E T Q D E+
Sbjct: 174 AHDD-DHNKPHLIYRQE-LKRNSFARSHKPCEVSENQMEKTALPSQSSRNTTGDVDIEEE 231
Query: 4152 VIERKARSRRAANS-------WDHYVEVLVVADTKMYEYHGRSLEDYVLTLFSTVASIYR 3994
+ R R +S + YVEV+V AD KM +HG++L+ YVLTL S VA+IY+
Sbjct: 232 AVFRLEGERSQLHSRNKRFLSYPRYVEVMVTADAKMVHHHGQNLQHYVLTLMSIVAAIYK 291
Query: 3993 HQSLRASXXXXXXXXXXXKTENAGPRITQNAQQTLQDFCRWQQYYNDPDDSSVQHHDVAI 3814
S+ +E GP I+ NA TL++FC WQQ N PDD+ HHD A+
Sbjct: 292 DSSIGNLINIVIVKLVVIHSEQEGPVISFNAATTLRNFCLWQQSQNVPDDAHPSHHDTAV 351
Query: 3813 LLTRKDICRSQGKCDTLGLAELGTMCDMQKSCAIIEDNGLSAAFTIAHELGHVFSIPHDD 3634
L+TR+DIC ++ KCDTLGLAELGT+CD +SC+I E+NGLSAAFTIAHELGHVF++PHDD
Sbjct: 352 LITREDICGAKEKCDTLGLAELGTLCDPSRSCSISEENGLSAAFTIAHELGHVFNVPHDD 411
Query: 3633 ERKCSTYMPVNKVCKFQSTKFDKTQFQNNFHIMAPTLEYNTHPWSWSPCSAGMLERFLEN 3454
KC + ++ +H+MAPTL Y+T PW+WS CS + FL+
Sbjct: 412 SFKCK-----------------EAGIKHQYHVMAPTLNYHTSPWTWSACSQKHITEFLDT 454
Query: 3453 NRGQTQCLFDQPVERRYYEDVFVRDEPGKKYDAHQQCKFVFGPASELCPYMPTCRRLWCA 3274
G +CL D+P R Y PG YD ++QC+ +FGP S++CPY+ CRRLWC
Sbjct: 455 GHG--ECLLDKPNGRTY---DLSPQLPGSVYDGNRQCELMFGPGSQVCPYLKHCRRLWCT 509
Query: 3273 TFYGSQMGCRTQHMPWADGTPCDESRSMFCHHGACVRLAPESLTKIDGQWGDWRSWGECS 3094
+ G GCRTQHMP ADGT C M CH G CV E+ +DG+WG W + CS
Sbjct: 510 SAEGVHKGCRTQHMPLADGTSC--GPGMHCHRGLCVTRDMET-RPVDGEWGPWGPYSSCS 566
Query: 3093 RTCGGGVQKGLRDCDSPKPRNGGKYCVGQRERYRSCNTQECPWDTQPYREVQCSEFNNKD 2914
RTCGGG++ R CD P+PRNGG+YCVG+R ++RSCNT CP + +RE QCS+F+ K
Sbjct: 567 RTCGGGIKSTARLCDRPEPRNGGRYCVGRRMKFRSCNTDSCPKGKRDFREKQCSDFDGKH 626
Query: 2913 IGIQGVASTNTHWVPKYANVAPNERCKLYCRLSGSAAFYLLRDKVVDGTPCDRNGDDICV 2734
I G+ N W+PKY+ +A +RCKLYCR++G+ +FY L+D+V DGTPC +DICV
Sbjct: 627 FDINGL-PPNVRWLPKYSGIAVKDRCKLYCRVAGTTSFYQLKDRVADGTPCGTETNDICV 685
Query: 2733 AGACMPAGCDHQLHSTLRRDKCGVCGGDDSSCKVVKGTFNEQGTFGYNEVMKIPAGSANI 2554
G C AGCDH L+S +RDKCGVCGGD+SSC+ + G FN +GYN V+KIPAG+ NI
Sbjct: 686 QGLCRQAGCDHVLNSKAKRDKCGVCGGDNSSCQTLAGVFN-SAHYGYNVVVKIPAGATNI 744
Query: 2553 DIRQKGYNNMKEDDNYLSLRAANGEFLLNGHFQVSLARQQIAFQDTVLEYSGSDAIIERI 2374
+I Q Y+ EDDNYL+L G FLLNG+F VS+A+++I Q V EYSGS+ IERI
Sbjct: 745 EILQHSYSGRPEDDNYLALSDTQGNFLLNGNFVVSMAKKEINIQGAVFEYSGSNNSIERI 804
Query: 2373 NGTGPIRSDIYVHVLSVGS-HPPDISYEYMTAAVPNAVIRPISSALYLWRVTDTWTECDR 2197
N T + +++ + VL VG+ + PD+ Y + N I S+ L+ W W +C +
Sbjct: 805 NSTDRLEAELVLQVLCVGNLYNPDVRYSF------NIPIEERSN-LFSWDPYGPWQDCTK 857
Query: 2196 ACRGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRWITEDVSSCSAKCG 2017
C+G +K+ C+ S H D NC ++ P T CN+DC RW S CS++CG
Sbjct: 858 MCQGLHRRKIACVRKSDHAVVSDHNCGHLPMPLFVTEKCNMDCELRWHIIGKSDCSSQCG 917
Query: 2016 SGQKRQRVSCVK--MEGDRQTPASEHLCDRNSKPSDIASCYIDCSGRKWNYGEWTSCSET 1843
G + V C+K + + P + C KP C+ C +W+Y EW+ CS +
Sbjct: 918 QGYRTLDVHCMKYSVHKGQAVPVGDQYCGDQLKPPSREPCHGSCVLTRWHYSEWSQCSRS 977
Query: 1842 CGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWVYGHWSECSRSCDG 1663
CG K R+SYCV+ R+ ES C RE CN PCP W WSEC +C
Sbjct: 978 CGGGDKT-RESYCVNGFGHRLAESEC-RELPRVVLENCNEFPCPSWATSEWSECPVTCGK 1035
Query: 1662 GVKMRHAQCLDAAD--RETHTSRCGPAQTQEHCNEHACTWWQFGVWSDCSAKCGDGVQYR 1489
G+K R C + D R+ + ++ C AC W G W C+A CG G Q R
Sbjct: 1036 GMKQRQVWCQLSEDPMRDGFCNASTKPESLRPCELRACASWHVGPWGSCTATCGHGYQMR 1095
Query: 1488 DANC-TDRHRSVLPEHRCLKMEKIITKPCHRESC------------------------PK 1384
C ++ ++L + C + ++P R+ C +
Sbjct: 1096 AVKCISEIFGTMLDDRECPQ----ASRPSDRQDCILAPCLAIPEVGATSLPAIPLGRAAQ 1151
Query: 1383 YKLGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRN 1204
++ G W+ CSVSC G +R VSC + D S C RPA+ C C W+
Sbjct: 1152 WRHGSWTPCSVSCGRGSQARYVSCRDAHDEVADESNCAHL-PRPAAVSLC-FSPCGEWQA 1209
Query: 1203 TDWSACSVSCGIGHRERTTECIYREQSVDASFCGDTKMPETSQTCHLLPC---------T 1051
WS CS SCG G R C+ Q VD S+C P T Q C L C +
Sbjct: 1210 GYWSPCSASCGHGKTTRRVLCVNYHQLVDESYCDPEGRPVTEQECSLAACPPLYSRAPSS 1269
Query: 1050 SWKPSH---------------------------------WSPCSVTCGSGIQTRSVSCTR 970
S +PSH W CS +C G+Q R+V C +
Sbjct: 1270 SEQPSHVPSRNVPLTHKPGENQDQGAQLSIRGNQWRTGPWGACSRSCAGGLQHRAVVC-Q 1328
Query: 969 GSEGTIVDEYFCDRNTRPRLKKTCEK---------------DTCDG-------------- 877
+G CD +++P + C TC G
Sbjct: 1329 DEDGRSATS--CDGSSKPPESRHCGSGPCPHWNYGDWGECTQTCGGGVKSRFVICQFPNG 1386
Query: 876 -------------PRVLQ-KLQADVPPIRWATGPWTACSATCGNGTQRRLLKCRDHV-RD 742
P ++Q L A + W GPW +CSA+CG G + R + C D R
Sbjct: 1387 QMTQEHSCELPKPPSMMQCHLHACPEDVSWYRGPWKSCSASCGKGVKYREVLCIDQFQRK 1446
Query: 741 LPDEYCNHLDKEVSTRNCRLRDCSYWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTI 562
L ++YC+HL K + + CR C WK +W+EC TCG+ VQQ R V C G +
Sbjct: 1447 LEEKYCSHLHKPRTHKACRSGRCPSWKANKWKECSVTCGSGVQQ-REVYCRLRGTG--RV 1503
Query: 561 LKDVDCDVQKRPTSARNCRLEPCPKGEEHIGSWIIGDWSKCSASCGGGWXXXXXXXXXXX 382
+D+ CD RP R C + C + + W GDW CS SC
Sbjct: 1504 SEDM-CDPSTRPQGQRQCWRQDCMRYQ-----WTTGDWLDCSTSC-------------KK 1544
Query: 381 CDETRKPKMFD----KCNEELCPPLT---------NNSWQISPWT----HCSVSCGGGVQ 253
+ R K + + NE LC PLT N + S T C+ +CG
Sbjct: 1545 KETYRLVKCVNEQNVQANESLCDPLTKPLSIKKCRNPHCKYSVVTGDSSQCAGNCGFTSP 1604
Query: 252 RRKIWCEDVLSGRKQDDIECSEIKPREQRDCEMPPCRSHY 133
++ +C + S +K +++P +C + P Y
Sbjct: 1605 QKITYCTKIQSSKKH---TFHQLRPVVYGECPVIPSPQAY 1641
Score = 263 bits (673), Expect = 2e-68
Identities = 190/684 (27%), Positives = 271/684 (38%), Gaps = 82/684 (11%)
Frame = -1
Query: 2223 TDTWTECDRAC-RGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRWITE 2047
T W+EC C +G + +++ C + D C KP ++ R C + W
Sbjct: 1023 TSEWSECPVTCGKGMKQRQVWC--QLSEDPMRDGFCNASTKP-ESLRPCELRACASWHVG 1079
Query: 2046 DVSSCSAKCGSGQKRQRVSCVK-----MEGDRQTPASEHLCDRNSKPSDIASCYI-DCS- 1888
SC+A CG G + + V C+ M DR+ C + S+PSD C + C
Sbjct: 1080 PWGSCTATCGHGYQMRAVKCISEIFGTMLDDRE-------CPQASRPSDRQDCILAPCLA 1132
Query: 1887 --------------GR--KWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGRE 1756
GR +W +G WT CS +CG G R C D + DES C
Sbjct: 1133 IPEVGATSLPAIPLGRAAQWRHGSWTPCSVSCG-RGSQARYVSCRDAHDEVADESNCAHL 1191
Query: 1755 QKEATERECNRIPCPRWVYGHWSECSRSCDGGVKMRHAQCLDAADR--ETHTSRCGPAQT 1582
+ A C PC W G+WS CS SC G R C++ E++ G T
Sbjct: 1192 PRPAAVSLCFS-PCGEWQAGYWSPCSASCGHGKTTRRVLCVNYHQLVDESYCDPEGRPVT 1250
Query: 1581 QEHCNEHAC------------------------------------------TWWQFGVWS 1528
++ C+ AC W+ G W
Sbjct: 1251 EQECSLAACPPLYSRAPSSSEQPSHVPSRNVPLTHKPGENQDQGAQLSIRGNQWRTGPWG 1310
Query: 1527 DCSAKCGDGVQYRDANCTDRH-RSVLPEHRCLKMEKIITKPCHRESCPKYKLGEWSQCSV 1351
CS C G+Q+R C D RS K + ++ C CP + G+W +C+
Sbjct: 1311 ACSRSCAGGLQHRAVVCQDEDGRSATSCDGSSKPPE--SRHCGSGPCPHWNYGDWGECTQ 1368
Query: 1350 SCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCP---FWRNTDWSACSV 1180
+C G SR V C NG C +P S C+L CP W W +CS
Sbjct: 1369 TCGGGVKSRFVICQFPNGQMTQEHSCELP--KPPSMMQCHLHACPEDVSWYRGPWKSCSA 1426
Query: 1179 SCGIGHRERTTECIYR-EQSVDASFCGDTKMPETSQTCHLLPCTSWKPSHWSPCSVTCGS 1003
SCG G + R CI + ++ ++ +C P T + C C SWK + W CSVTCGS
Sbjct: 1427 SCGKGVKYREVLCIDQFQRKLEEKYCSHLHKPRTHKACRSGRCPSWKANKWKECSVTCGS 1486
Query: 1002 GIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWAT 823
G+Q R V C G V E CD +TRP+ ++ C + C +W T
Sbjct: 1487 GVQQREVYCRLRGTGR-VSEDMCDPSTRPQGQRQCWRQDC-------------MRYQWTT 1532
Query: 822 GPWTACSATCGNGTQRRLLKCRDHVRDLPDE-YCNHLDKEVSTRNCRLRDCSYWKMA-EW 649
G W CS +C RL+KC + +E C+ L K +S + CR C Y + +
Sbjct: 1533 GDWLDCSTSCKKKETYRLVKCVNEQNVQANESLCDPLTKPLSIKKCRNPHCKYSVVTGDS 1592
Query: 648 EECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPKGEE--- 478
+C CG Q + C + + Q RP C + P P+ +
Sbjct: 1593 SQCAGNCGFTSPQ-KITYCTKIQSSKKHTFH------QLRPVVYGECPVIPSPQAYKCDL 1645
Query: 477 ----HIGSWIIGDWSKCSASCGGG 418
H+ +W +G WSKCS +CG G
Sbjct: 1646 RSCLHVATWKVGKWSKCSVTCGIG 1669
Score = 256 bits (654), Expect = 4e-66
Identities = 179/669 (26%), Positives = 259/669 (37%), Gaps = 86/669 (12%)
Frame = -1
Query: 1872 YGEWTSCSETCGSNGKMHRKSYCVDDSNRRV-DESLCGREQKEATERECNRIPCP-RWVY 1699
YG W C++ C G RK CV S+ V + CG E + C RW
Sbjct: 849 YGPWQDCTKMC--QGLHRRKIACVRKSDHAVVSDHNCGHLPMPLFVTEKCNMDCELRWHI 906
Query: 1698 GHWSECSRSCDGGVKMRHAQCLDAADRETHTSRCGPAQTQEHCNEH-------------A 1558
S+CS C G + C+ + H + P Q +C +
Sbjct: 907 IGKSDCSSQCGQGYRTLDVHCMKYS---VHKGQAVPVGDQ-YCGDQLKPPSREPCHGSCV 962
Query: 1557 CTWWQFGVWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIITKPCHRESCPKYK 1378
T W + WS CS CG G + R++ C + L E C ++ +++ + C+ CP +
Sbjct: 963 LTRWHYSEWSQCSRSCGGGDKTRESYCVNGFGHRLAESECRELPRVVLENCNEFPCPSWA 1022
Query: 1377 LGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNTD 1198
EWS+C V+C G R+V C D C AS +P S + C L C W
Sbjct: 1023 TSEWSECPVTCGKGMKQRQVWCQLSEDPMRD-GFCN-ASTKPESLRPCELRACASWHVGP 1080
Query: 1197 WSACSVSCGIGHRERTTECIYR--EQSVDASFCGDTKMPETSQTCHLLPCTS-------- 1048
W +C+ +CG G++ R +CI +D C P Q C L PC +
Sbjct: 1081 WGSCTATCGHGYQMRAVKCISEIFGTMLDDRECPQASRPSDRQDCILAPCLAIPEVGATS 1140
Query: 1047 -----------WKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKT 901
W+ W+PCSV+CG G Q R VSC R + + DE C RP
Sbjct: 1141 LPAIPLGRAAQWRHGSWTPCSVSCGRGSQARYVSC-RDAHDEVADESNCAHLPRPAAVSL 1199
Query: 900 CEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATCGNGTQRRLLKCRDHVRDLPDEYCN 721
C P W G W+ CSA+CG+G R + C ++ + + + YC+
Sbjct: 1200 CFS----------------PCGEWQAGYWSPCSASCGHGKTTRRVLCVNYHQLVDESYCD 1243
Query: 720 HLDKEVSTRNCRLRDC------------------------------------------SY 667
+ V+ + C L C +
Sbjct: 1244 PEGRPVTEQECSLAACPPLYSRAPSSSEQPSHVPSRNVPLTHKPGENQDQGAQLSIRGNQ 1303
Query: 666 WKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPK 487
W+ W C +C +Q R V C ++ GR+ CD +P +R+C PCP
Sbjct: 1304 WRTGPWGACSRSCAGGLQH-RAVVC--QDEDGRSA---TSCDGSSKPPESRHCGSGPCPH 1357
Query: 486 GEEHIGSWIIGDWSKCSASCGGGWXXXXXXXXXXXCDETR-------KPKMFDKCNEELC 328
W GDW +C+ +CGGG T+ KP +C+ C
Sbjct: 1358 -------WNYGDWGECTQTCGGGVKSRFVICQFPNGQMTQEHSCELPKPPSMMQCHLHAC 1410
Query: 327 PPLTNNSWQISPWTHCSVSCGGGVQRRKIWCEDVLSGRKQDDIECSEI-KPREQRDCEMP 151
P + SW PW CS SCG GV+ R++ C D RK ++ CS + KPR + C
Sbjct: 1411 PE--DVSWYRGPWKSCSASCGKGVKYREVLCIDQFQ-RKLEEKYCSHLHKPRTHKACRSG 1467
Query: 150 PCRSHYHNK 124
C S NK
Sbjct: 1468 RCPSWKANK 1476
Score = 218 bits (555), Expect = 1e-54
Identities = 164/642 (25%), Positives = 236/642 (36%), Gaps = 122/642 (19%)
Frame = -1
Query: 2232 WRVTDTWTECDRAC-RGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDC---- 2068
W V W C C G Q + + C+ DR C +P C
Sbjct: 1076 WHV-GPWGSCTATCGHGYQMRAVKCISEIFGTMLDDRECPQASRPSDRQDCILAPCLAIP 1134
Query: 2067 --------------STRWITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRN 1930
+ +W + CS CG G + + VSC + A E C
Sbjct: 1135 EVGATSLPAIPLGRAAQWRHGSWTPCSVSCGRGSQARYVSCRDAHDE---VADESNCAHL 1191
Query: 1929 SKPSDIASCYIDCSGRKWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQK 1750
+P+ ++ C+ C +W G W+ CS +CG +GK R+ CV+ ++ VDES C E +
Sbjct: 1192 PRPAAVSLCFSPCG--EWQAGYWSPCSASCG-HGKTTRRVLCVN-YHQLVDESYCDPEGR 1247
Query: 1749 EATERECNRIPCP------------------------------------------RWVYG 1696
TE+EC+ CP +W G
Sbjct: 1248 PVTEQECSLAACPPLYSRAPSSSEQPSHVPSRNVPLTHKPGENQDQGAQLSIRGNQWRTG 1307
Query: 1695 HWSECSRSCDGGVKMRHAQCLDAADRETHTSRCGPAQTQE--HCNEHACTWWQFGVWSDC 1522
W CSRSC GG++ R C D D + TS G ++ E HC C W +G W +C
Sbjct: 1308 PWGACSRSCAGGLQHRAVVCQDE-DGRSATSCDGSSKPPESRHCGSGPCPHWNYGDWGEC 1366
Query: 1521 SAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIITKPCHRESCPK---YKLGEWSQCSV 1351
+ CG GV+ R C + + EH C + CH +CP+ + G W CS
Sbjct: 1367 TQTCGGGVKSRFVICQFPNGQMTQEHSCELPKPPSMMQCHLHACPEDVSWYRGPWKSCSA 1426
Query: 1350 SCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNTDWSACSVSCG 1171
SC G R V C+ +++ C +P +H+ C G CP W+ W CSV+CG
Sbjct: 1427 SCGKGVKYREVLCIDQFQRKLEEKYCSHLH-KPRTHKACRSGRCPSWKANKWKECSVTCG 1485
Query: 1170 IGHRERTTECIYREQS-VDASFCGDTKMPETSQTCHLLPCT--SWKPSHWSPCSVTCGSG 1000
G ++R C R V C + P+ + C C W W CS +C
Sbjct: 1486 SGVQQREVYCRLRGTGRVSEDMCDPSTRPQGQRQCWRQDCMRYQWTTGDWLDCSTSCKKK 1545
Query: 999 IQTRSVSCTRGSEGTIVDEYFCDRNTRP-RLKK-----------TCEKDTCDG------P 874
R V C + +E CD T+P +KK T + C G P
Sbjct: 1546 ETYRLVKCVN-EQNVQANESLCDPLTKPLSIKKCRNPHCKYSVVTGDSSQCAGNCGFTSP 1604
Query: 873 RVLQ---KLQA---------------DVPPI-----------------RWATGPWTACSA 799
+ + K+Q+ + P I W G W+ CS
Sbjct: 1605 QKITYCTKIQSSKKHTFHQLRPVVYGECPVIPSPQAYKCDLRSCLHVATWKVGKWSKCSV 1664
Query: 798 TCGNGTQRRLLKCRDHVRDLPDEYCNHLDKEVSTRNCRLRDC 673
TCG G R + CR P + C K + + C DC
Sbjct: 1665 TCGIGIMERRVACRTE-NGWPSDLCLKRLKPDAQKKCYANDC 1705
Score = 186 bits (472), Expect = 5e-45
Identities = 129/428 (30%), Positives = 183/428 (42%), Gaps = 25/428 (5%)
Frame = -1
Query: 2061 RWITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYIDCSGR 1882
+W T +CS C G + + V C +G T CD +SKP + C SG
Sbjct: 1303 QWRTGPWGACSRSCAGGLQHRAVVCQDEDGRSATS-----CDGSSKPPESRHCG---SGP 1354
Query: 1881 --KWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPR 1708
WNYG+W C++TCG G R C + + E C K + +C+ CP
Sbjct: 1355 CPHWNYGDWGECTQTCGG-GVKSRFVICQFPNGQMTQEHSC-ELPKPPSMMQCHLHACPE 1412
Query: 1707 ---WVYGHWSECSRSCDGGVKMRHAQCLDAADRETHTSRCG---PAQTQEHCNEHACTWW 1546
W G W CS SC GVK R C+D R+ C +T + C C W
Sbjct: 1413 DVSWYRGPWKSCSASCGKGVKYREVLCIDQFQRKLEEKYCSHLHKPRTHKACRSGRCPSW 1472
Query: 1545 QFGVWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKII-TKPCHRESCPKYK--L 1375
+ W +CS CG GVQ R+ C R + E C + + C R+ C +Y+
Sbjct: 1473 KANKWKECSVTCGSGVQQREVYCRLRGTGRVSEDMCDPSTRPQGQRQCWRQDCMRYQWTT 1532
Query: 1374 GEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNT-D 1198
G+W CS SC+ + R V CV+ + + SLC + +P S + C C + T D
Sbjct: 1533 GDWLDCSTSCKKKETYRLVKCVNEQNVQANESLCDPLT-KPLSIKKCRNPHCKYSVVTGD 1591
Query: 1197 WSACSVSCGIGHRERTTECIYREQSVDASF----------CGDTKMPETSQTCHLLPC-- 1054
S C+ +CG ++ T C + S +F C P+ + C L C
Sbjct: 1592 SSQCAGNCGFTSPQKITYCTKIQSSKKHTFHQLRPVVYGECPVIPSPQAYK-CDLRSCLH 1650
Query: 1053 -TSWKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDG 877
+WK WS CSVTCG GI R V+C R G D C + +P +K C + C
Sbjct: 1651 VATWKVGKWSKCSVTCGIGIMERRVAC-RTENGWPSD--LCLKRLKPDAQKKCYANDCKL 1707
Query: 876 PRVLQKLQ 853
++LQ
Sbjct: 1708 LTTCKELQ 1715
Score = 66.2 bits (160), Expect = 7e-09
Identities = 45/185 (24%), Positives = 78/185 (41%), Gaps = 10/185 (5%)
Frame = -1
Query: 2238 YLWRVTDTWTECDRACRGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTR 2059
Y W D W +C +C+ +++ +L+ + Q+++ C + KP + N C
Sbjct: 1528 YQWTTGD-WLDCSTSCKKKETYRLVKCVNEQNVQANESLCDPLTKPLSIKKCRNPHCKYS 1586
Query: 2058 WITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQ------TPASEHLCDRNSKPS----DIA 1909
+T D S C+ CG ++ C K++ ++ P C P D+
Sbjct: 1587 VVTGDSSQCAGNCGFTSPQKITYCTKIQSSKKHTFHQLRPVVYGECPVIPSPQAYKCDLR 1646
Query: 1908 SCYIDCSGRKWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATEREC 1729
SC + W G+W+ CS TCG G M R+ C ++ D LC + K +++C
Sbjct: 1647 SCLHVAT---WKVGKWSKCSVTCGI-GIMERRVACRTENGWPSD--LCLKRLKPDAQKKC 1700
Query: 1728 NRIPC 1714
C
Sbjct: 1701 YANDC 1705
>gi|7242979|dbj|BAA92550.1| KIAA1312 protein [Homo sapiens]
Length = 1471
Score = 982 bits (2538), Expect = 0.0
Identities = 550/1527 (36%), Positives = 764/1527 (50%), Gaps = 109/1527 (7%)
Frame = -1
Query: 4398 SIVNLCDSEDGLYGMLALPSGIHTVEPIISGNGTEHDGASRHRQHLV-RKFDPMHFKSF- 4225
++++LC G+ G G + +EP+ S + E D +++ H++ R+ P S
Sbjct: 6 AVISLCS---GMLGTFRSHDGDYFIEPLQSMDEQE-DEEEQNKPHIIYRRSAPQREPSTG 61
Query: 4224 -------DHLNSTSVNETETTVATWQDQWE------------------------DVIERK 4138
+H N S ++ +T W ++ D K
Sbjct: 62 RHACDTSEHKNRHSKDKKKTRARKWGERINLAGDVAALNSGLATEAFSAYGNKTDNTREK 121
Query: 4137 ARSRRAAN--SWDHYVEVLVVADTKMYEYHGRSLEDYVLTLFSTVASIYRHQSLRASXXX 3964
RR S+ +VEVLVVAD +M YHG +L+ Y+LTL S VASIY+ S+
Sbjct: 122 RTHRRTKRFLSYPRFVEVLVVADNRMVSYHGENLQHYILTLMSIVASIYKDPSIGNLINI 181
Query: 3963 XXXXXXXXKTENAGPRITQNAQQTLQDFCRWQQYYNDPDDSSVQHHDVAILLTRKDICRS 3784
E GP I+ NAQ TL++FC+WQ N P HHD A+LLTR+DICR+
Sbjct: 182 VIVNLIVIHNEQDGPSISFNAQTTLKNFCQWQHSKNSPGGI---HHDTAVLLTRQDICRA 238
Query: 3783 QGKCDTLGLAELGTMCDMQKSCAIIEDNGLSAAFTIAHELGHVFSIPHDDERKCSTYMPV 3604
KCDTLGLAELGT+CD +SC+I ED+GLS AFTIAHELGHVF++PHDD KC
Sbjct: 239 HDKCDTLGLAELGTICDPYRSCSISEDSGLSTAFTIAHELGHVFNMPHDDNNKC------ 292
Query: 3603 NKVCKFQSTKFDKTQFQNNFHIMAPTLEYNTHPWSWSPCSAGMLERFLENNRGQTQCLFD 3424
K + K + H+MAPTL + T+PW WS CS + FL+ G+ CL +
Sbjct: 293 ----KEEGVKSPQ-------HVMAPTLNFYTNPWMWSKCSRKYITEFLDTGYGE--CLLN 339
Query: 3423 QPVERRYYEDVFVRDEPGKKYDAHQQCKFVFGPASELCPYMPTCRRLWCATFYGSQMGCR 3244
+P R Y V + PG Y+ ++QC+ +FGP S++CPYM CRRLWC G GCR
Sbjct: 340 EPESRPYPLPVQL---PGILYNVNKQCELIFGPGSQVCPYMMQCRRLWCNNVNGVHKGCR 396
Query: 3243 TQHMPWADGTPCDESRSMFCHHGACVRLAPESLTKIDGQWGDWRSWGECSRTCGGGVQKG 3064
TQH PWADGT C+ + C +G CV + + DG WG W +G CSRTCGGG++
Sbjct: 397 TQHTPWADGTECEPGKH--CKYGFCVPKEMD-VPVTDGSWGSWSPFGTCSRTCGGGIKTA 453
Query: 3063 LRDCDSPKPRNGGKYCVGQRERYRSCNTQECPWDTQPYREVQCSEFNNKDIGIQGVASTN 2884
+R+C+ P+P+NGGKYCVG+R +++SCNT+ C + +R+ QC+ F+ K I G+ N
Sbjct: 454 IRECNRPEPKNGGKYCVGRRMKFKSCNTEPCLKQKRDFRDEQCAHFDGKHFNINGLLP-N 512
Query: 2883 THWVPKYANVAPNERCKLYCRLSGSAAFYLLRDKVVDGTPCDRNGDDICVAGACMPAGCD 2704
WVPKY+ + +RCKL+CR++G+ A+Y LRD+V+DGTPC ++ +DICV G C AGCD
Sbjct: 513 VRWVPKYSGILMKDRCKLFCRVAGNTAYYQLRDRVIDGTPCGQDTNDICVQGLCRQAGCD 572
Query: 2703 HQLHSTLRRDKCGVCGGDDSSCKVVKGTFNEQGTFGYNEVMKIPAGSANIDIRQKGYNNM 2524
H L+S RRDKCGVCGGD+SSCK V GTFN +GYN V++IPAG+ NID+RQ ++
Sbjct: 573 HVLNSKARRDKCGVCGGDNSSCKTVAGTFNTV-HYGYNTVVRIPAGATNIDVRQHSFSGE 631
Query: 2523 KEDDNYLSLRAANGEFLLNGHFQVSLARQQIAFQDTVLEYSGSDAIIERINGTGPIRSDI 2344
+DDNYL+L ++ GEFLLNG+F V++A+++I + V+EYSGS+ +ERIN T I ++
Sbjct: 632 TDDDNYLALSSSKGEFLLNGNFVVTMAKREIRIGNAVVEYSGSETAVERINSTDRIEQEL 691
Query: 2343 YVHVLSVGS-HPPDISYEYMTAAVPNAVIRPISSALYLWRVTDTWTECDRACRGQQSQKL 2167
+ VLSVG + PD+ Y + N I Y W W C + C+G++ +KL
Sbjct: 692 LLQVLSVGKLYNPDVRYSF------NIPIEDKPQQFY-WNSHGPWQACSKPCQGERKRKL 744
Query: 2166 MCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRWITEDVSSCSAKCGSGQKRQRVSC 1987
+C S D+ C + +P T C DC RW S CSA+CG G + + C
Sbjct: 745 VCTRESDQLTVSDQRCDRLPQPGHITEPCGTDCDLRWHVASRSECSAQCGLGYRTLDIYC 804
Query: 1986 VKME--GDRQTPASEHLCDRNSKPSDIASCYIDCSGRKWNYGEWTSCSETCGSNGKMHRK 1813
K + + C + KPS+ C +C+ W Y WT CS++C G R+
Sbjct: 805 AKYSRLDGKTEKVDDGFCSSHPKPSNREKCSGECNTGGWRYSAWTECSKSC-DGGTQRRR 863
Query: 1812 SYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWVYGHWSECSRSCDGGVKMRHAQCL 1633
+ CV+ N +D+S C ++K +R C+ PCP+W G WSEC +C G K R C
Sbjct: 864 AICVNTRNDVLDDSKCTHQEKVTIQR-CSEFPCPQWKSGDWSECLVTCGKGHKHRQVWCQ 922
Query: 1632 DAADRETHTSRCGP---AQTQEHCNEHACTWWQFGVWSDCSAKCGDGVQYRDANC-TDRH 1465
DR + C P + + C + C WQ G W CS CG G Q R C +
Sbjct: 923 FGEDR-LNDRMCDPETKPTSMQTCQQPECASWQAGPWGQCSVTCGQGYQLRAVKCIIGTY 981
Query: 1464 RSVLPEHRC-LKMEKIITKPCHRESC------------------PKYKLGEWSQCSVSCE 1342
SV+ ++ C T+ C SC +++ G W+ CS +C
Sbjct: 982 MSVVDDNDCNAATRPTDTQDCELPSCHPPPAAPETRRSTYSAPRTQWRFGSWTPCSATCG 1041
Query: 1341 DGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNTDWSACSVSCGIGH 1162
G R VSC NG+ D S C T RP + + C++ C W+ DWS+CSV+CG G
Sbjct: 1042 KGTRMRYVSCRDENGSVADESACATL-PRPVAKEECSVTPCGQWKALDWSSCSVTCGQGR 1100
Query: 1161 RERTTECI-YREQSVDASFCGDTKMPETSQTCHLLPC----------------------- 1054
R C+ Y + +D S C +PET Q C + PC
Sbjct: 1101 ATRQVMCVNYSDHVIDRSECDQDYIPETDQDCSMSPCPQRTPDSGLAQHPFQNEDYRPRS 1160
Query: 1053 -----------TSWKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLK 907
W+ W CS TC G Q R V C + T D C +P +
Sbjct: 1161 ASPSRTHVLGGNQWRTGPWGACSSTCAGGSQRRVVVCQDENGYTAND---CVERIKPDEQ 1217
Query: 906 KTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATCGNGTQRRLLKC-RDHVRDLPDE 730
+ CE C +WA G W C+ CG G + RL+ C R + PD
Sbjct: 1218 RACESGPCP---------------QWAYGNWGECTKLCGGGIRTRLVVCQRSNGERFPDL 1262
Query: 729 YCNHLDKEVSTRNCRLRDCSY---WKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTIL 559
C LDK C C + W W C +CG +Q RNV C+ A+DG L
Sbjct: 1263 SCEILDKPPDREQCNTHACPHDAAWSTGPWSSCSVSCGRGHKQ-RNVYCM-AKDGSH--L 1318
Query: 558 KDVDCDVQKRPTSARNCRLEPCPKGEEHIGSWIIGDWSKCSASCGGGWXXXXXXXXXXXC 379
+ C +P R CR CPK W G WS+CS SCG G
Sbjct: 1319 ESDYCKHLAKPHGHRKCRGGRCPK-------WKAGAWSQCSVSCGRGVQQRHVGCQIGTH 1371
Query: 378 DETR--------KPKMFDKCNEELCPPLTNNSWQISPWTHCSVSCGGGVQRRKIWCEDVL 223
R +P+ C CP T W+ W C+ +CG G + RK+ C D
Sbjct: 1372 KIARETECNPYTRPESERDCQGPRCPLYT---WRAEEWQECTKTCGEGSRYRKVVCVDD- 1427
Query: 222 SGRKQDDIECSEIK-PREQRDCEMPPC 145
+ + C K P ++ C + PC
Sbjct: 1428 NKNEVHGARCDVSKRPVDRESCSLQPC 1454
Score = 254 bits (649), Expect = 1e-65
Identities = 160/595 (26%), Positives = 245/595 (40%), Gaps = 62/595 (10%)
Frame = -1
Query: 2232 WRVTDTWTECDRAC-RGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRW 2056
W+ D W+EC C +G + +++ C + +DR C KP +C++ W
Sbjct: 898 WKSGD-WSECLVTCGKGHKHRQVWC--QFGEDRLNDRMCDPETKPTSMQTCQQPECAS-W 953
Query: 2055 ITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYI------- 1897
CS CG G + + V C+ G + ++ C+ ++P+D C +
Sbjct: 954 QAGPWGQCSVTCGQGYQLRAVKCII--GTYMSVVDDNDCNAATRPTDTQDCELPSCHPPP 1011
Query: 1896 ----------DCSGRKWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKE 1747
+W +G WT CS TCG +M S C D++ DES C +
Sbjct: 1012 AAPETRRSTYSAPRTQWRFGSWTPCSATCGKGTRMRYVS-CRDENGSVADESACATLPRP 1070
Query: 1746 ATERECNRIPCPRWVYGHWSECSRSCDGGVKMRHAQCLDAADRETHTSRCGP---AQTQE 1576
+ EC+ PC +W WS CS +C G R C++ +D S C +T +
Sbjct: 1071 VAKEECSVTPCGQWKALDWSSCSVTCGQGRATRQVMCVNYSDHVIDRSECDQDYIPETDQ 1130
Query: 1575 HCNEHAC----------------------------------TWWQFGVWSDCSAKCGDGV 1498
C+ C W+ G W CS+ C G
Sbjct: 1131 DCSMSPCPQRTPDSGLAQHPFQNEDYRPRSASPSRTHVLGGNQWRTGPWGACSSTCAGGS 1190
Query: 1497 QYRDANCTDRHRSVLPEHRCL-KMEKIITKPCHRESCPKYKLGEWSQCSVSCEDGWSSRR 1321
Q R C D + + C+ +++ + C CP++ G W +C+ C G +R
Sbjct: 1191 QRRVVVCQDENGYTAND--CVERIKPDEQRACESGPCPQWAYGNWGECTKLCGGGIRTRL 1248
Query: 1320 VSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPF---WRNTDWSACSVSCGIGHRERT 1150
V C NG C D+P + CN CP W WS+CSVSCG GH++R
Sbjct: 1249 VVCQRSNGERFPDLSCEIL-DKPPDREQCNTHACPHDAAWSTGPWSSCSVSCGRGHKQRN 1307
Query: 1149 TECIYREQS-VDASFCGDTKMPETSQTCHLLPCTSWKPSHWSPCSVTCGSGIQTRSVSCT 973
C+ ++ S +++ +C P + C C WK WS CSV+CG G+Q R V C
Sbjct: 1308 VYCMAKDGSHLESDYCKHLAKPHGHRKCRGGRCPKWKAGAWSQCSVSCGRGVQQRHVGCQ 1367
Query: 972 RGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATC 793
G+ I E C+ TRP ++ C+ GPR P W W C+ TC
Sbjct: 1368 IGTH-KIARETECNPYTRPESERDCQ-----GPRC--------PLYTWRAEEWQECTKTC 1413
Query: 792 GNGTQRRLLKC-RDHVRDLPDEYCNHLDKEVSTRNCRLRDCSY-WKMAEWEECPA 634
G G++ R + C D+ ++ C+ + V +C L+ C Y W EW E P+
Sbjct: 1414 GEGSRYRKVVCVDDNKNEVHGARCDVSKRPVDRESCSLQPCEYVWITGEWSEVPS 1468
>gi|50754509|ref|XP_414417.1| PREDICTED: similar to a disintegrin and
metalloproteinase with thrombospondin motifs 9 isoform 1
preproprotein [Gallus gallus]
Length = 4349
Score = 929 bits (2400), Expect = 0.0
Identities = 511/1370 (37%), Positives = 717/1370 (52%), Gaps = 107/1370 (7%)
Frame = -1
Query: 4437 CIYRAHVKGVHQHS-IVNLCDSEDGLYGMLALPSGIHTVEPIISGNGT---EHDGAS--- 4279
C YR HV +H+ +++LC G+ G G + VEP++S EH+
Sbjct: 525 CFYRGHVNARPRHTAVISLCS---GMLGTFKSDDGDYFVEPLLSLEQEYEEEHNKPHLVY 581
Query: 4278 RHR------------------QHLVRKFDPMHFKSFDHLNSTSVNETETTVATWQ----- 4168
RHR +H +K H++ + S+ +++TE + +
Sbjct: 582 RHRTPPTNSSGDRQTCDTPDHEHSHKKSKRKHWRK-QWVESSLLSDTEMLKHSLEVNPFS 640
Query: 4167 ---DQWEDVIERKARSR-RAANSWDHYVEVLVVADTKMYEYHGRSLEDYVLTLFSTVASI 4000
++ + E+K+ R + S+ +VEV+VVAD++M YHG +L+ YVLTL S VASI
Sbjct: 641 ADSNETGNASEKKSHRRTKRFLSYPRFVEVMVVADSRMVAYHGANLQHYVLTLMSIVASI 700
Query: 3999 YRHQSLRASXXXXXXXXXXXKTENAGPRITQNAQQTLQDFCRWQQYYNDPDDSSVQHHDV 3820
Y+ S+ E GP I+ NAQ TL++FC+WQQ N P+ S +QH D
Sbjct: 701 YKDPSIGNLINIVIVKLVVIHNEQDGPAISYNAQTTLKNFCQWQQSQNHPEGSHLQH-DT 759
Query: 3819 AILLTRKDICRSQGKCDTLGLAELGTMCDMQKSCAIIEDNGLSAAFTIAHELGHVFSIPH 3640
A+L+TR+DICR+ KCDTLGLAELGT+CD +SC+I EDNGLS AFTIAHELGHVF++PH
Sbjct: 760 AVLVTRQDICRAHDKCDTLGLAELGTVCDPYRSCSISEDNGLSTAFTIAHELGHVFNMPH 819
Query: 3639 DDERKCSTYMPVNKVCKFQSTKFDKTQFQNNFHIMAPTLEYNTHPWSWSPCSAGMLERFL 3460
DD KC + +N H+MAPTL + T+PW WS CS + FL
Sbjct: 820 DDNHKCK-----------------EDGGKNQQHVMAPTLNFYTNPWMWSKCSRKYITEFL 862
Query: 3459 ENNRGQTQCLFDQPVERRYYEDVFVRDEPGKKYDAHQQCKFVFGPASELCPYMPT--CRR 3286
+ G+ CL D+P R Y + PG YD ++QC+ +FGP S++CPYM + CRR
Sbjct: 863 DTGYGE--CLLDEPSSRTY---ALPQQLPGLIYDVNKQCELIFGPGSQVCPYMVSMQCRR 917
Query: 3285 LWCATFYGSQMGCRTQHMPWADGTPCDESRSMFCHHGACVRLAPESLTKIDGQWGDWRSW 3106
LWC G+ GCRTQH PWADGT C+ + C G CV E+ +DG WG W +
Sbjct: 918 LWCINIDGAHKGCRTQHTPWADGTECEPGKH--CRFGMCVPKEREAPV-VDGAWGTWSPF 974
Query: 3105 GECSRTCGGGVQKGLRDCDSPKPRNGGKYCVGQRERYRSCNTQECPWDTQPYREVQCSEF 2926
G CSRTCGGG++ +R+C+ P+P+NGGKYCVG+R +++SCNT+ C + +R+ QC++F
Sbjct: 975 GTCSRTCGGGIKTAIRECNRPEPKNGGKYCVGRRMKFKSCNTEPCSKLKKDFRDEQCADF 1034
Query: 2925 NNKDIGIQGVASTNTHWVPKYANVAPNERCKLYCRLSGSAAFYLLRDKVVDGTPCDRNGD 2746
+ K I G+ TN WVPKY+ + +RCKL+CR++G+ A+Y LRD+V+DGTPC + +
Sbjct: 1035 DGKHFNINGLP-TNVRWVPKYSGILMKDRCKLFCRVAGNTAYYQLRDRVIDGTPCGPDTN 1093
Query: 2745 DICVAGACMPAGCDHQLHSTLRRDKCGVCGGDDSSCKVVKGTFNEQGTFGYNEVMKIPAG 2566
DICV G C AGCDH L+S RRDKCGVCGGD+SSCK V GTFN +GYN V++IPAG
Sbjct: 1094 DICVQGLCRQAGCDHVLNSKARRDKCGVCGGDNSSCKTVAGTFNTV-HYGYNVVVRIPAG 1152
Query: 2565 SANIDIRQKGYNNMKEDDNYLSLRAANGEFLLNGHFQVSLARQQIAFQDTVLEYSGSDAI 2386
+ NID+RQ Y+ EDDNYL+L + G+F+LNG F VS+ +++I + V+EYSGSD
Sbjct: 1153 ATNIDVRQHSYSGKPEDDNYLALSNSQGDFILNGDFVVSMFKREIKVGNAVIEYSGSDNA 1212
Query: 2385 IERINGTGPIRSDIYVHVLSVGS-HPPDISYEYMTAAVPNAVIRPISSALYLWRVTDTWT 2209
IERIN T I +I + VLSVG+ + PD+ Y + N I Y W W
Sbjct: 1213 IERINSTDRIEQEITLQVLSVGNLYNPDVRYTF------NIPIEDKPQQFY-WNAYGPWQ 1265
Query: 2208 ECDRACRGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRWITEDVSSCS 2029
C + C+G++ +K +C S D+ C + +P T C +C RW S C+
Sbjct: 1266 PCSKLCQGERKRKPVCTRESDQLTVSDQRCDRIPQPDPITEPCGTECELRWHIARRSECT 1325
Query: 2028 AKCGSGQKRQRVSCVK---MEGDRQTPASEHLCDRNSKPSDIASCYIDCSGRKWNYGEWT 1858
A+CG G + + C K +EG + + C +KPS C DC+ W Y WT
Sbjct: 1326 AQCGLGYRMLEIYCSKYNRLEG-KTEKVDDRFCSSQAKPSTREKCTGDCNVGGWRYSAWT 1384
Query: 1857 SCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWVYGHWSECS 1678
CS++CG G R++ CV N +D+S C +++K +R C+ CP+W G WSEC
Sbjct: 1385 ECSKSCG-GGTRRRRAMCVSTYNDVLDDSKCSQQEKLTVQR-CSDFLCPQWKTGDWSECL 1442
Query: 1677 RSCDGGVKMRHAQCLDAADRETHTSRCGP---AQTQEHCNEHACTWWQFGVWSDCSAKCG 1507
+C G K R C DR + C P ++ + C + C WQ G W C+ CG
Sbjct: 1443 VTCGKGHKHRQTWCQFGEDR-LNDRFCDPETKPESVQTCQQQECAAWQVGPWGQCTMTCG 1501
Query: 1506 DGVQYRDANC-TDRHRSVLPEHRCLKMEK-IITKPCHRESCP------------------ 1387
G Q R C + SV+ ++ C K T+ C +CP
Sbjct: 1502 QGYQMRAVKCVVGTYMSVVDDNECNAATKPTDTQDCEIAACPPHPNSPEAKRSVSGVHRT 1561
Query: 1386 KYKLGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWR 1207
+++ G W+ CS +C G R VSC G+ D S C +P++ + C + C W+
Sbjct: 1562 QWRFGSWTPCSATCGKGTRMRYVSCRDEQGSVADESAC-FHLPKPSATEMCTVTPCGQWK 1620
Query: 1206 NTDWSACSVSCGIGHRERTTECI-YREQSVDASFCGDTKMPETSQTCHLLPC-------- 1054
+WS+CSV+CG G R CI Y +Q VD S C +P T Q C + PC
Sbjct: 1621 ALEWSSCSVTCGQGKATRQVICIDYSDQLVDRSECDPDDLPATEQDCSMSPCHPNSHDYG 1680
Query: 1053 -------------------------------TSWKPSHWSPCSVTCGSGIQTRSVSCTRG 967
W+ W CS TC G Q R V C
Sbjct: 1681 RPIHPFLYPDHRLKLHPGGSPNRNRAHIPGGNQWRIGPWGACSSTCAGGFQRRVVVCQDE 1740
Query: 966 SEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATCGN 787
+ T + CD T+P +++CE C +WA G W C+ CG
Sbjct: 1741 NGYTANN---CDEKTKPMEQRSCESGPCP---------------QWAYGNWGECTKPCGA 1782
Query: 786 GTQRRLLKC-RDHVRDLPDEYCNHLDKEVSTRNCRLRDC---SYWKMAEW 649
GT+ RL+ C R + D C LDK C ++DC + W W
Sbjct: 1783 GTRTRLVVCQRPNGERFTDLSCEILDKPPDREQCNVQDCPRDAAWSAGPW 1832
Score = 276 bits (707), Expect = 3e-72
Identities = 171/578 (29%), Positives = 245/578 (41%), Gaps = 59/578 (10%)
Frame = -1
Query: 1701 YGHWSECSRSCDGGVKMRHAQCLDAADRETHTS-RCG----PAQTQEHCNEHACTWWQFG 1537
YG W CS+ C G K R C +D+ T + RC P E C W
Sbjct: 1261 YGPWQPCSKLCQGERK-RKPVCTRESDQLTVSDQRCDRIPQPDPITEPCGTECELRWHIA 1319
Query: 1536 VWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKII----TKPCHRESCPK----- 1384
S+C+A+CG G + + C+ +R E + K++ KP RE C
Sbjct: 1320 RRSECTAQCGLGYRMLEIYCSKYNRL---EGKTEKVDDRFCSSQAKPSTREKCTGDCNVG 1376
Query: 1383 -YKLGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWR 1207
++ W++CS SC G RR CVS +D S C + + Q C+ CP W+
Sbjct: 1377 GWRYSAWTECSKSCGGGTRRRRAMCVSTYNDVLDDSKC--SQQEKLTVQRCSDFLCPQWK 1434
Query: 1206 NTDWSACSVSCGIGHRERTTECIYREQSVDASFCGDTKMPETSQTCHLLPCTSWKPSHWS 1027
DWS C V+CG GH+ R T C + E ++ FC PE+ QTC C +W+ W
Sbjct: 1435 TGDWSECLVTCGKGHKHRQTWCQFGEDRLNDRFCDPETKPESVQTCQQQECAAWQVGPWG 1494
Query: 1026 PCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTC----DGPRVLQK 859
C++TCG G Q R+V C G+ ++VD+ C+ T+P + CE C + P +
Sbjct: 1495 QCTMTCGQGYQMRAVKCVVGTYMSVVDDNECNAATKPTDTQDCEIAACPPHPNSPEAKRS 1554
Query: 858 LQADVPPIRWATGPWTACSATCGNGTQRRLLKCRDHVRDLPDEY-CNHLDKEVSTRNCRL 682
+ V +W G WT CSATCG GT+ R + CRD + DE C HL K +T C +
Sbjct: 1555 VSG-VHRTQWRFGSWTPCSATCGKGTRMRYVSCRDEQGSVADESACFHLPKPSATEMCTV 1613
Query: 681 RDCSYWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRL 502
C WK EW C TCG + +R V C+ D ++ +CD P + ++C +
Sbjct: 1614 TPCGQWKALEWSSCSVTCGQG-KATRQVICIDYSD---QLVDRSECDPDDLPATEQDCSM 1669
Query: 501 EPCPKGEEHIG--------------------------------SWIIGDWSKCSASCGGG 418
PC G W IG W CS++C GG
Sbjct: 1670 SPCHPNSHDYGRPIHPFLYPDHRLKLHPGGSPNRNRAHIPGGNQWRIGPWGACSSTCAGG 1729
Query: 417 WX------XXXXXXXXXXCDETRKPKMFDKCNEELCPPLTNNSWQISPWTHCSVSCGGGV 256
+ CDE KP C CP W W C+ CG G
Sbjct: 1730 FQRRVVVCQDENGYTANNCDEKTKPMEQRSCESGPCP-----QWAYGNWGECTKPCGAGT 1784
Query: 255 QRRKIWCEDVLSGRKQDDIECSEI-KPREQRDCEMPPC 145
+ R + C+ +G + D+ C + KP ++ C + C
Sbjct: 1785 RTRLVVCQRP-NGERFTDLSCEILDKPPDREQCNVQDC 1821
Score = 273 bits (698), Expect = 3e-71
Identities = 177/588 (30%), Positives = 256/588 (43%), Gaps = 58/588 (9%)
Frame = -1
Query: 2034 CSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIAS-CYIDCSGRKWNYGEWT 1858
CS C G+++++ C + E D+ T S+ CDR +P I C +C R W+ +
Sbjct: 1267 CSKLC-QGERKRKPVCTR-ESDQLT-VSDQRCDRIPQPDPITEPCGTECELR-WHIARRS 1322
Query: 1857 SCSETCGSNGKMHRKSYC-----VDDSNRRVDESLCGREQKEATERECNR-IPCPRWVYG 1696
C+ CG +M + YC ++ +VD+ C + K +T +C W Y
Sbjct: 1323 ECTAQCGLGYRM-LEIYCSKYNRLEGKTEKVDDRFCSSQAKPSTREKCTGDCNVGGWRYS 1381
Query: 1695 HWSECSRSCDGGVKMRHAQCLDAADRETHTSRCGPAQ--TQEHCNEHACTWWQFGVWSDC 1522
W+ECS+SC GG + R A C+ + S+C + T + C++ C W+ G WS+C
Sbjct: 1382 AWTECSKSCGGGTRRRRAMCVSTYNDVLDDSKCSQQEKLTVQRCSDFLCPQWKTGDWSEC 1441
Query: 1521 SAKCGDGVQYRDANCT---DR--HRSVLPEHRCLKMEKIITKPCHRESCPKYKLGEWSQC 1357
CG G ++R C DR R PE K E + T C ++ C +++G W QC
Sbjct: 1442 LVTCGKGHKHRQTWCQFGEDRLNDRFCDPE---TKPESVQT--CQQQECAAWQVGPWGQC 1496
Query: 1356 SVSCEDGWSSRRVSCVSGNGTEV-DMSLCGTASDRPASHQTCNLGTCP------------ 1216
+++C G+ R V CV G V D + C A+ +P Q C + CP
Sbjct: 1497 TMTCGQGYQMRAVKCVVGTYMSVVDDNECNAAT-KPTDTQDCEIAACPPHPNSPEAKRSV 1555
Query: 1215 ------FWRNTDWSACSVSCGIGHRERTTECIYREQSV-DASFCGDTKMPETSQTCHLLP 1057
WR W+ CS +CG G R R C + SV D S C P ++ C + P
Sbjct: 1556 SGVHRTQWRFGSWTPCSATCGKGTRMRYVSCRDEQGSVADESACFHLPKPSATEMCTVTP 1615
Query: 1056 CTSWKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDG 877
C WK WS CSVTCG G TR V C S+ +VD CD + P ++ C C
Sbjct: 1616 CGQWKALEWSSCSVTCGQGKATRQVICIDYSD-QLVDRSECDPDDLPATEQDCSMSPCHP 1674
Query: 876 --------------PRVLQKLQADVPPIR----------WATGPWTACSATCGNGTQRRL 769
P KL P R W GPW ACS+TC G QRR+
Sbjct: 1675 NSHDYGRPIHPFLYPDHRLKLHPGGSPNRNRAHIPGGNQWRIGPWGACSSTCAGGFQRRV 1734
Query: 768 LKCRDHVRDLPDEYCNHLDKEVSTRNCRLRDCSYWKMAEWEECPATCGTHVQQSRNVTCV 589
+ C+D C+ K + R+C C W W EC CG ++R V C
Sbjct: 1735 VVCQDE-NGYTANNCDEKTKPMEQRSCESGPCPQWAYGNWGECTKPCGAGT-RTRLVVC- 1791
Query: 588 SAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPKGEEHIGSWIIGDWS 445
+G R D+ C++ +P C ++ CP+ +W G WS
Sbjct: 1792 QRPNGER--FTDLSCEILDKPPDREQCNVQDCPRD----AAWSAGPWS 1833
Score = 171 bits (432), Expect = 2e-40
Identities = 111/439 (25%), Positives = 173/439 (39%), Gaps = 23/439 (5%)
Frame = -1
Query: 1374 GEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNTDW 1195
G W CS C+ + V + V C + C W
Sbjct: 1262 GPWQPCSKLCQGERKRKPVCTRESDQLTVSDQRCDRIPQPDPITEPCGTECELRWHIARR 1321
Query: 1194 SACSVSCGIGHRERTTECIY------REQSVDASFCGDTKMPETSQTCHLLPCT--SWKP 1039
S C+ CG+G+R C + + VD FC P T + C C W+
Sbjct: 1322 SECTAQCGLGYRMLEIYCSKYNRLEGKTEKVDDRFCSSQAKPSTREKC-TGDCNVGGWRY 1380
Query: 1038 SHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQK 859
S W+ CS +CG G + R C + ++D+ C + + +++ C C
Sbjct: 1381 SAWTECSKSCGGGTRRRRAMCV-STYNDVLDDSKCSQQEKLTVQR-CSDFLCP------- 1431
Query: 858 LQADVPPIRWATGPWTACSATCGNGTQRRLLKCRDHVRDLPDEYCNHLDKEVSTRNCRLR 679
+W TG W+ C TCG G + R C+ L D +C+ K S + C+ +
Sbjct: 1432 --------QWKTGDWSECLVTCGKGHKHRQTWCQFGEDRLNDRFCDPETKPESVQTCQQQ 1483
Query: 678 DCSYWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLE 499
+C+ W++ W +C TCG Q R V CV +++ D +C+ +PT ++C +
Sbjct: 1484 ECAAWQVGPWGQCTMTCGQGYQM-RAVKCVVGTY--MSVVDDNECNAATKPTDTQDCEIA 1540
Query: 498 PCPKGEE-----------HIGSWIIGDWSKCSASCGGGWXXXXXX---XXXXXCDETRKP 361
CP H W G W+ CSA+CG G DE+
Sbjct: 1541 ACPPHPNSPEAKRSVSGVHRTQWRFGSWTPCSATCGKGTRMRYVSCRDEQGSVADESACF 1600
Query: 360 KMFDKCNEELCPPLTNNSWQISPWTHCSVSCGGGVQRRKIWCEDVLSGRKQDDIECS-EI 184
+ E+C W+ W+ CSV+CG G R++ C D S + D EC +
Sbjct: 1601 HLPKPSATEMCTVTPCGQWKALEWSSCSVTCGQGKATRQVICID-YSDQLVDRSECDPDD 1659
Query: 183 KPREQRDCEMPPCRSHYHN 127
P ++DC M PC + H+
Sbjct: 1660 LPATEQDCSMSPCHPNSHD 1678
Score = 132 bits (331), Expect = 1e-28
Identities = 108/420 (25%), Positives = 173/420 (40%), Gaps = 24/420 (5%)
Frame = -1
Query: 1338 GWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNTDWSACSVSCGIGHR 1159
G R V C++ G V+ C +P + C G CP W++ DW + I +
Sbjct: 2041 GQRHRTVYCLTKEGRHVEEDYCKHLV-KPNVQKKCRGGRCPKWKSGDWGQNELV--IIDK 2097
Query: 1158 ERTTECIYREQSVDASFC-GDTKMPETSQTCHLLPCTSWKPSHWSPCSVTCGSGIQTRSV 982
+ ++ + + +F G+ + +Q+ L C S + S SP + I+ +
Sbjct: 2098 SKRSKIPTFLRVIGVNFMQGEKERRSNAQSLAALGCRSIEHSEHSPNI----NPIRGKPD 2153
Query: 981 SCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACS 802
GS+ ++ L+++ + G + P P+ CS
Sbjct: 2154 PAEAGSKNSLC------------LQRSGNSSSAGGTADHRPPHQPAPLTHLC--PFPQCS 2199
Query: 801 ATCGNGTQRRLLKCRDHVRDLPDEYCNHLDKEVSTRNCRLRDCSY--WKMAEWEECPATC 628
+CG G Q+R ++C P C+ + + R+C+L +C W EW+ C TC
Sbjct: 2200 VSCGRGVQQRAVQCHGGA---PTAACDPASQPAAQRDCQLPECPTHRWAAGEWQACLKTC 2256
Query: 627 GTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPKGEEHIGSWIIGDW 448
G V+ R V CV D + + CD KRP +C L PC E+I WI G+W
Sbjct: 2257 GEAVRY-RKVFCV---DESKQVQSSAHCDASKRPLEMESCGLPPC----EYI--WITGEW 2306
Query: 447 SKCSASCGGGWXXXXXXXXXXXCDETR--------------KPKMFDKCNEELCPPLTNN 310
S+CS +CG G+ + +P C CP +
Sbjct: 2307 SECSVTCGKGYRQRLVSCSEIYTGKDHYEYGYQNTVSCPGTQPPNIQPCYLGECP--VSA 2364
Query: 309 SWQISPWTHCSVSCGGGVQRRKIWCEDVLSGRKQDDIEC-SEIKPREQR------DCEMP 151
SW++S W CSV+CG GV R + C L+ Q C +++KP E+R DCE+P
Sbjct: 2365 SWRVSNWGSCSVTCGVGVMHRSVQC---LTNDDQLSSLCHADLKPEERRTCHNVHDCELP 2421
Score = 121 bits (303), Expect = 2e-25
Identities = 80/240 (33%), Positives = 109/240 (45%), Gaps = 22/240 (9%)
Frame = -1
Query: 1719 PCPRWVYGHWSECSRSCDGGVKMRHAQCLDAADRETHTSRCGPAQ---TQEHCNEHACTW 1549
P P + +CS SC GV+ R QC A T+ C PA Q C C
Sbjct: 2186 PAPLTHLCPFPQCSVSCGRGVQQRAVQCHGGAP----TAACDPASQPAAQRDCQLPECPT 2241
Query: 1548 --WQFGVWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRC------LKMEKIITKPCHRES 1393
W G W C CG+ V+YR C D + V C L+ME PC
Sbjct: 2242 HRWAAGEWQACLKTCGEAVRYRKVFCVDESKQVQSSAHCDASKRPLEMESCGLPPCEY-- 2299
Query: 1392 CPKYKLGEWSQCSVSCEDGWSSRRVSC---VSGN-----GTEVDMSLCGTASDRPASHQT 1237
+ GEWS+CSV+C G+ R VSC +G G + +S GT +P + Q
Sbjct: 2300 --IWITGEWSECSVTCGKGYRQRLVSCSEIYTGKDHYEYGYQNTVSCPGT---QPPNIQP 2354
Query: 1236 CNLGTCPF---WRNTDWSACSVSCGIGHRERTTECIYREQSVDASFCGDTKMPETSQTCH 1066
C LG CP WR ++W +CSV+CG+G R+ +C+ + + +S C PE +TCH
Sbjct: 2355 CYLGECPVSASWRVSNWGSCSVTCGVGVMHRSVQCLTNDDQL-SSLCHADLKPEERRTCH 2413
Score = 115 bits (288), Expect = 1e-23
Identities = 105/413 (25%), Positives = 153/413 (36%), Gaps = 28/413 (6%)
Frame = -1
Query: 2025 KCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYIDCSGR--KWNYGEWTSC 1852
K GQ+ + V C+ EG E C KP+ C GR KW G+W
Sbjct: 2037 KQSRGQRHRTVYCLTKEGRH---VEEDYCKHLVKPNVQKKCR---GGRCPKWKSGDW--- 2087
Query: 1851 SETCGSNGKMHRKSYCVDDSNRRVDESLC---------GREQKEATERECNRIPCPRWVY 1699
G N + +D S R + G +++ + + + C +
Sbjct: 2088 ----GQN-----ELVIIDKSKRSKIPTFLRVIGVNFMQGEKERRSNAQSLAALGCRSIEH 2138
Query: 1698 GHWSECSRSCDGGVKMRHAQCLDAADRETHTSRCGPAQTQEHCNEHA-CTWWQFGVWSDC 1522
S G A ++ + + T +H H + C
Sbjct: 2139 SEHSPNINPIRGKPDPAEAGSKNSLCLQRSGNSSSAGGTADHRPPHQPAPLTHLCPFPQC 2198
Query: 1521 SAKCGDGVQYRDANCTDRHRSVLPEHRC-LKMEKIITKPCHRESCPKYK--LGEWSQCSV 1351
S CG GVQ R C P C + + C CP ++ GEW C
Sbjct: 2199 SVSCGRGVQQRAVQC----HGGAPTAACDPASQPAAQRDCQLPECPTHRWAAGEWQACLK 2254
Query: 1350 SCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPF-WRNTDWSACSVSC 1174
+C + R+V CV +V S AS RP ++C L C + W +WS CSV+C
Sbjct: 2255 TCGEAVRYRKVFCVD-ESKQVQSSAHCDASKRPLEMESCGLPPCEYIWITGEWSECSVTC 2313
Query: 1173 GIGHRERTTECI--------YREQSVDASFCGDTKMPETSQTCHLLPC---TSWKPSHWS 1027
G G+R+R C Y + C T+ P Q C+L C SW+ S+W
Sbjct: 2314 GKGYRQRLVSCSEIYTGKDHYEYGYQNTVSCPGTQPPNI-QPCYLGECPVSASWRVSNWG 2372
Query: 1026 PCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEK-DTCDGPR 871
CSVTCG G+ RSV C + C + +P ++TC C+ PR
Sbjct: 2373 SCSVTCGVGVMHRSVQCLTNDDQL---SSLCHADLKPEERRTCHNVHDCELPR 2422
Score = 110 bits (274), Expect = 4e-22
Identities = 91/289 (31%), Positives = 121/289 (41%), Gaps = 9/289 (3%)
Frame = -1
Query: 1413 KPCHRESCPKYKLGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTC 1234
+P H+ + P L + QCSVSC G R V C G T + C AS +PA+ + C
Sbjct: 2181 RPPHQPA-PLTHLCPFPQCSVSCGRGVQQRAVQCHGGAPT----AACDPAS-QPAAQRDC 2234
Query: 1233 NLGTCPF--WRNTDWSACSVSCGIGHRERTTECIYREQSVDAS-FCGDTKMPETSQTCHL 1063
L CP W +W AC +CG R R C+ + V +S C +K P ++C L
Sbjct: 2235 QLPECPTHRWAAGEWQACLKTCGEAVRYRKVFCVDESKQVQSSAHCDASKRPLEMESCGL 2294
Query: 1062 LPCT-SWKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDT 886
PC W WS CSVTCG G + R VSC+ G EY +
Sbjct: 2295 PPCEYIWITGEWSECSVTCGKGYRQRLVSCSEIYTGKDHYEYGYQNTV-----------S 2343
Query: 885 CDG--PRVLQKLQADVPPI--RWATGPWTACSATCGNGTQRRLLKCRDHVRDLPDEYCNH 718
C G P +Q P+ W W +CS TCG G R ++C + D C+
Sbjct: 2344 CPGTQPPNIQPCYLGECPVSASWRVSNWGSCSVTCGVGVMHRSVQCLTN-DDQLSSLCHA 2402
Query: 717 LDKEVSTRNC-RLRDCSYWKMAEWEECPATCGTHVQQSRNVTCVSAEDG 574
K R C + DC E P +C V+ + VT EDG
Sbjct: 2403 DLKPEERRTCHNVHDC---------ELPRSC-NDVKSLKGVT----EDG 2437
Score = 74.3 bits (181), Expect = 3e-11
Identities = 64/242 (26%), Positives = 96/242 (39%), Gaps = 24/242 (9%)
Frame = -1
Query: 2208 ECDRAC-RGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNI-DCST-RWITEDVS 2038
+C +C RG Q + + C H + C +P A R C + +C T RW +
Sbjct: 2197 QCSVSCGRGVQQRAVQC-----HGGAPTAACDPASQPA-AQRDCQLPECPTHRWAAGEWQ 2250
Query: 2037 SCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYIDCSGRKWNYGEWT 1858
+C CG + ++V CV + +Q +S H CD + +P ++ SC + W GEW+
Sbjct: 2251 ACLKTCGEAVRYRKVFCV--DESKQVQSSAH-CDASKRPLEMESCGLPPCEYIWITGEWS 2307
Query: 1857 SCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCP----------- 1711
CS TCG G R C E G++ E + N + CP
Sbjct: 2308 ECSVTCG-KGYRQRLVSC--------SEIYTGKDHYEYGYQ--NTVSCPGTQPPNIQPCY 2356
Query: 1710 --------RWVYGHWSECSRSCDGGVKMRHAQCLDAADRETHTSRCG--PAQTQEHCNEH 1561
W +W CS +C GV R QCL D+ + P + + N H
Sbjct: 2357 LGECPVSASWRVSNWGSCSVTCGVGVMHRSVQCLTNDDQLSSLCHADLKPEERRTCHNVH 2416
Query: 1560 AC 1555
C
Sbjct: 2417 DC 2418
Score = 63.5 bits (153), Expect = 5e-08
Identities = 51/175 (29%), Positives = 67/175 (38%), Gaps = 14/175 (8%)
Frame = -1
Query: 669 YWKM-AEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPC 493
YW W+ C C Q R V + + + D CD +P EPC
Sbjct: 1257 YWNAYGPWQPCSKLC----QGERKRKPVCTRESDQLTVSDQRCDRIPQPDPIT----EPC 1308
Query: 492 PKGEEHIGSWIIGDWSKCSASCGGGWXXXXXXXXXXXCDETRKPKMFDKCNEELCPPLTN 313
G E W I S+C+A CG G+ E + K+ D+ P T
Sbjct: 1309 --GTECELRWHIARRSECTAQCGLGYRMLEIYCSKYNRLEGKTEKVDDRFCSSQAKPSTR 1366
Query: 312 NS---------WQISPWTHCSVSCGGGVQRRKIWC----EDVLSGRKQDDIECSE 187
W+ S WT CS SCGGG +RR+ C DVL DD +CS+
Sbjct: 1367 EKCTGDCNVGGWRYSAWTECSKSCGGGTRRRRAMCVSTYNDVL-----DDSKCSQ 1416
Score = 63.5 bits (153), Expect = 5e-08
Identities = 55/225 (24%), Positives = 85/225 (37%), Gaps = 43/225 (19%)
Frame = -1
Query: 2232 WRVTDTWTECDRAC-RGQQSQKLMCLDMST-------------------------HRQSH 2131
W+ + W+ C C +G+ +++++C+D S H SH
Sbjct: 1619 WKALE-WSSCSVTCGQGKATRQVICIDYSDQLVDRSECDPDDLPATEQDCSMSPCHPNSH 1677
Query: 2130 D--RNCQNVLKPKQATRM----------CNIDCSTRWITEDVSSCSAKCGSGQKRQRVSC 1987
D R L P ++ +I +W +CS+ C G +R+ V C
Sbjct: 1678 DYGRPIHPFLYPDHRLKLHPGGSPNRNRAHIPGGNQWRIGPWGACSSTCAGGFQRRVVVC 1737
Query: 1986 VKMEGDRQTPASEHLCDRNSKPSDIASCYIDCSG--RKWNYGEWTSCSETCGSNGKMHRK 1813
G + + CD +KP + SC SG +W YG W C++ CG+ G R
Sbjct: 1738 QDENG-----YTANNCDEKTKPMEQRSCE---SGPCPQWAYGNWGECTKPCGA-GTRTRL 1788
Query: 1812 SYCVDDSNRRVDESLCGREQKEATERECNRIPCPR---WVYGHWS 1687
C + R + C K +CN CPR W G WS
Sbjct: 1789 VVCQRPNGERFTDLSCEILDKPPDREQCNVQDCPRDAAWSAGPWS 1833
Score = 55.5 bits (132), Expect = 1e-05
Identities = 37/129 (28%), Positives = 57/129 (43%), Gaps = 3/129 (2%)
Frame = -1
Query: 2232 WRVTDTWTECDRACRGQ-QSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRW 2056
WR+ W C C G Q + ++C D + + + NC KP + R C +W
Sbjct: 1714 WRI-GPWGACSSTCAGGFQRRVVVCQDENGYTAN---NCDEKTKPMEQ-RSCESGPCPQW 1768
Query: 2055 ITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYI-DC-SGR 1882
+ C+ CG+G + + V C + G+R T S C+ KP D C + DC
Sbjct: 1769 AYGNWGECTKPCGAGTRTRLVVCQRPNGERFTDLS---CEILDKPPDREQCNVQDCPRDA 1825
Query: 1881 KWNYGEWTS 1855
W+ G W+S
Sbjct: 1826 AWSAGPWSS 1834
Score = 45.8 bits (107), Expect = 0.010
Identities = 24/63 (38%), Positives = 33/63 (52%)
Frame = -1
Query: 324 PLTNNSWQISPWTHCSVSCGGGVQRRKIWCEDVLSGRKQDDIECSEIKPREQRDCEMPPC 145
PLT+ + P+ CSVSCG GVQ+R + C D +P QRDC++P C
Sbjct: 2188 PLTH----LCPFPQCSVSCGRGVQQRAVQCHGGAPTAACDPAS----QPAAQRDCQLPEC 2239
Query: 144 RSH 136
+H
Sbjct: 2240 PTH 2242
>gi|29611731|sp|P59510|AT20_HUMAN ADAMTS-20 precursor (A disintegrin
and metalloproteinase with thrombospondin motifs 20)
(ADAM-TS 20) (ADAM-TS20)
gi|27463367|gb|AAO15766.1| a disintegrin-like and metalloprotease
with thrombospondin type 1 motifs 20 [Homo sapiens]
Length = 1911
Score = 923 bits (2385), Expect = 0.0
Identities = 517/1498 (34%), Positives = 742/1498 (49%), Gaps = 64/1498 (4%)
Frame = -1
Query: 4437 CIYRAHVKGVHQH-SIVNLCDSEDGLYGMLALPSGIHTVEPIISGNGTEHDGASRHRQHL 4261
C YR V + ++V+LC GL G +G + +EPI+ +G E++ ++ HL
Sbjct: 129 CFYRGQVNSQEDYKAVVSLCG---GLTGTFKGQNGEYFLEPIMKADGNEYEDG-HNKPHL 184
Query: 4260 VRKFDP----MHFKSFDHLNSTSVNETETTVATWQDQWEDVI------------------ 4147
+ + D + + ++ + + ET T+ + ED+
Sbjct: 185 IYRQDLNNSFLQTLKYCSVSESQIKETSLPFHTYSNMNEDLNVMKERVLGHTSKNVPLKD 244
Query: 4146 ERKARSRRAANSWDHYVEVLVVADTKMYEYHGRSLEDYVLTLFSTVASIYRHQSLRASXX 3967
ER+ ++ S+ Y+E++V AD K+ HG +L++Y+LTL S VA+IY+ S+
Sbjct: 245 ERRHSRKKRLISYPRYIEIMVTADAKVVSAHGSNLQNYILTLMSIVATIYKDPSIGNLIH 304
Query: 3966 XXXXXXXXXKTENAGPRITQNAQQTLQDFCRWQQYYNDPDDSSVQHHDVAILLTRKDICR 3787
E GP I + TL++FC WQQ ND DD HHD A+L+TR+DIC
Sbjct: 305 IVVVKLVMIHREEEGPVINFDGATTLKNFCSWQQTQNDLDDVHPSHHDTAVLITREDICS 364
Query: 3786 SQGKCDTLGLAELGTMCDMQKSCAIIEDNGLSAAFTIAHELGHVFSIPHDDERKCSTYMP 3607
S+ KC+TLGL+ LGT+CD +SC I E+ GL +AFTIAHELGH + HDD +C M
Sbjct: 365 SKEKCNTLGLSYLGTICDPLQSCFINEEKGLISAFTIAHELGHTLGVQHDDNPRCKE-MK 423
Query: 3606 VNKVCKFQSTKFDKTQFQNNFHIMAPTLEYNTHPWSWSPCSAGMLERFLENNRGQTQCLF 3427
V K +H+MAP L ++ PWSWS CS + FL+ G+ CL
Sbjct: 424 VTK-----------------YHVMAPALSFHMSPWSWSNCSRKYVTEFLDTGYGE--CLL 464
Query: 3426 DQPVERRYYEDVFVRDEPGKKYDAHQQCKFVFGPASELCPYMPTCRRLWCATFYGSQMGC 3247
D+P E Y + PG +YD ++QC+ FGP S++CP++ C LWC + GC
Sbjct: 465 DKPDEEIYN---LPSELPGSRYDGNKQCELAFGPGSQMCPHINICMHLWCTSTEKLHKGC 521
Query: 3246 RTQHMPWADGTPCDESRSMFCHHGACVRLAPESLTKIDGQWGDWRSWGECSRTCGGGVQK 3067
TQH+P ADGT C M C HG CV E+ ++G+WG W + CSRTCGGG++
Sbjct: 522 FTQHVPPADGTDCGPG--MHCRHGLCVNKETET-RPVNGEWGPWEPYSSCSRTCGGGIES 578
Query: 3066 GLRDCDSPKPRNGGKYCVGQRERYRSCNTQECPWDTQPYREVQCSEFNNKDIGIQGVAST 2887
R C+ P+PRNGG YCVG+R ++RSCNT CP TQ +RE QCS+FN K + I G+ S
Sbjct: 579 ATRRCNRPEPRNGGNYCVGRRMKFRSCNTDSCPKGTQDFREKQCSDFNGKHLDISGIPS- 637
Query: 2886 NTHWVPKYANVAPNERCKLYCRLSGSAAFYLLRDKVVDGTPCDRNGDDICVAGACMPAGC 2707
N W+P+Y+ + +RCKLYC+++G+ FYLL+D V DGTPC DICV G CM AGC
Sbjct: 638 NVRWLPRYSGIGTKDRCKLYCQVAGTNYFYLLKDMVEDGTPCGTETHDICVQGQCMAAGC 697
Query: 2706 DHQLHSTLRRDKCGVCGGDDSSCKVVKGTFNEQGTFGYNEVMKIPAGSANIDIRQKGYNN 2527
DH L+S+ + DKCGVCGGD+SSCK + G FN +GYN V+KIPAG+ N+DIRQ Y+
Sbjct: 698 DHVLNSSAKIDKCGVCGGDNSSCKTITGVFN-SSHYGYNVVVKIPAGATNVDIRQYSYSG 756
Query: 2526 MKEDDNYLSLRAANGEFLLNGHFQVSLARQQIAFQD--TVLEYSGSDAIIERINGTGPIR 2353
+ DD+YL+L A G FL NG+F +S ++++I Q TV+EYSGS+ +ERIN T
Sbjct: 757 -QPDDSYLALSDAEGNFLFNGNFLLSTSKKEINVQGTRTVIEYSGSNNAVERINSTNRQE 815
Query: 2352 SDIYVHVLSVGS-HPPDISYEYMTAAVPNAVIRPISSALYLWRVTDTWTECDRACRGQQS 2176
++ + VL VG+ + PD+ Y + N + S ++ W W C + C+G Q
Sbjct: 816 KELILQVLCVGNLYNPDVHYSF------NIPLEE-RSDMFTWDPYGPWEGCTKMCQGLQR 868
Query: 2175 QKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTR-WITEDVSSCSAKCGSGQKRQ 1999
+ + C+ S H D+ C ++ P T+ CN DC R + S CS++CG G +
Sbjct: 869 RNITCIHKSDHSVVSDKECDHLPLPSFVTQSCNTDCELRGMLLAKKSECSSQCGQGYRTL 928
Query: 1998 RVSCVK--MEGDRQTPASEHLCDRNSKPSDIASCYIDCSGRKWNYGEWTSCSETCGSNGK 1825
+ C+K + + +H C KP C+ +C +W+Y EW+ CS +CG G+
Sbjct: 929 DIHCMKYSIHEGQTVQVDDHYCGDQLKPPTQELCHGNCVFTRWHYSEWSQCSRSCG-GGE 987
Query: 1824 MHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWVYGHWSECSRSCDGGVKMRH 1645
R+SYC+++ R+ ++ C +E T CN CP W WSEC +C G K R
Sbjct: 988 RSRESYCMNNFGHRLADNEC-QELSRVTRENCNEFSCPSWAASEWSECLVTCGKGTKQRQ 1046
Query: 1644 AQCLDAADR--ETHTSRCGPAQTQEHCNEHACTWWQFGVWSDCSAKCGDGVQYRDANCTD 1471
C D + + ++ C H C WQ G W C+ CG G Q RD C +
Sbjct: 1047 VWCQLNVDHLSDGFCNSSTKPESLSPCELHTCASWQVGPWGPCTTTCGHGYQMRDVKCVN 1106
Query: 1470 RHRS-VLPEHRCLKMEKIITKPCHRESC------------------------PKYKLGEW 1366
S VL + C + ++P R+SC +++ G W
Sbjct: 1107 ELASAVLEDTECHE----ASRPSDRQSCVLTPCSFISKLETALLPTVLIKKMAQWRHGSW 1162
Query: 1365 SQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNTDWSAC 1186
+ CSVSC G +R VSC D S C RPA C C W+ DWS C
Sbjct: 1163 TPCSVSCGRGTQARYVSCRDALDRIADESYCAHL-PRPAEIWDC-FTPCGEWQAGDWSPC 1220
Query: 1185 SVSCGIGHRERTTECIYREQSVDASFCGDTKMPETSQTCHLLPCTSWKPSHWSPCSVTCG 1006
S SCG G R C+ Q +D ++C P Q C L C P+H
Sbjct: 1221 SASCGHGKTTRQVLCMNYHQPIDENYCDPEVRPLMEQECSLAAC---PPAH--------- 1268
Query: 1005 SGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWA 826
+ + Y+ N P +K + + Q + V +W
Sbjct: 1269 ----------SHFPSSPVQPSYYLSTNL-PLTQKLEDNEN-------QVVHPSVRGNQWR 1310
Query: 825 TGPWTACSATCGNGTQRRLLKCRDHVRDLPDEYCNHLDKEVSTRNCRLRDCSYWKMAEWE 646
TGPW +CS++C G Q + C+D YC+ K + C C W W
Sbjct: 1311 TGPWGSCSSSCSGGLQHTAVVCQDE-NGQSASYCDAASKPPELQQCGPGPCPQWNYGNWG 1369
Query: 645 ECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPKGEEHIGS 466
EC TCG + +SR V C + IL+D +C++ +P S C + CP S
Sbjct: 1370 ECSQTCGGGI-KSRLVIC---QFPNGQILEDHNCEIVNKPPSVIQCHMHACPADV----S 1421
Query: 465 WIIGDWSKCSASCGGG--------WXXXXXXXXXXXCDETRKPKMFDKCNEELCPPLTNN 310
W W+ CSASCG G C + +KP C CP
Sbjct: 1422 WHQEPWTSCSASCGKGRKYREVFCIDQFQRKLEDTNCSQVQKPPTHKACRSVRCP----- 1476
Query: 309 SWQISPWTHCSVSCGGGVQRRKIWCEDVLSGRKQDDIECSEIKPREQRDCEMPPCRSH 136
SW+ + W CSV+CG GVQ+R ++C G+ +++ +P QR C C H
Sbjct: 1477 SWKANSWNECSVTCGSGVQQRDVYCRLKGVGQVVEEMCDQSTRPCSQRRCWSQDCVQH 1534
Score = 266 bits (679), Expect = 5e-69
Identities = 190/785 (24%), Positives = 313/785 (39%), Gaps = 87/785 (11%)
Frame = -1
Query: 2232 WRVTDTWTECDRACRG-QQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRW 2056
W ++ W++C R+C G ++S++ C++ HR + D CQ + + + CN W
Sbjct: 971 WHYSE-WSQCSRSCGGGERSRESYCMNNFGHRLA-DNECQELSRVTREN--CNEFSCPSW 1026
Query: 2055 ITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYIDCSGRKW 1876
+ S C CG G K+++V C ++ D S+ C+ ++KP ++ C + W
Sbjct: 1027 AASEWSECLVTCGKGTKQRQVWC-QLNVDH---LSDGFCNSSTKPESLSPCELHTCA-SW 1081
Query: 1875 NYGEWTSCSETCGSNGKMHRKSYCVDD-SNRRVDESLCGREQKEATERECNRIPCP---- 1711
G W C+ TCG +G R CV++ ++ ++++ C + + + C PC
Sbjct: 1082 QVGPWGPCTTTCG-HGYQMRDVKCVNELASAVLEDTECHEASRPSDRQSCVLTPCSFISK 1140
Query: 1710 ---------------RWVYGHWSECSRSCDGGVKMRHAQCLDAADRETHTSRCG----PA 1588
+W +G W+ CS SC G + R+ C DA DR S C PA
Sbjct: 1141 LETALLPTVLIKKMAQWRHGSWTPCSVSCGRGTQARYVSCRDALDRIADESYCAHLPRPA 1200
Query: 1587 QTQEHCNEHACTWWQFGVWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIITKP 1408
+ + C WQ G WS CSA CG G R C + H+ + + ++ ++ +
Sbjct: 1201 EIWDCFTP--CGEWQAGDWSPCSASCGHGKTTRQVLCMNYHQPIDENYCDPEVRPLMEQE 1258
Query: 1407 CHRESCP------------------------------------------KYKLGEWSQCS 1354
C +CP +++ G W CS
Sbjct: 1259 CSLAACPPAHSHFPSSPVQPSYYLSTNLPLTQKLEDNENQVVHPSVRGNQWRTGPWGSCS 1318
Query: 1353 VSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNTDWSACSVSC 1174
SC G V C NG S C AS +P Q C G CP W +W CS +C
Sbjct: 1319 SSCSGGLQHTAVVCQDENGQSA--SYCDAAS-KPPELQQCGPGPCPQWNYGNWGECSQTC 1375
Query: 1173 GIGHRERTTECIYRE-QSVDASFCGDTKMPETSQTCHLLPC---TSWKPSHWSPCSVTCG 1006
G G + R C + Q ++ C P + CH+ C SW W+ CS +CG
Sbjct: 1376 GGGIKSRLVICQFPNGQILEDHNCEIVNKPPSVIQCHMHACPADVSWHQEPWTSCSASCG 1435
Query: 1005 SGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWA 826
G + R V C + + D C + +P K C C W
Sbjct: 1436 KGRKYREVFCIDQFQRKLEDTN-CSQVQKPPTHKACRSVRCPS---------------WK 1479
Query: 825 TGPWTACSATCGNGTQRRLLKCR-DHVRDLPDEYCNHLDKEVSTRNCRLRDCSYWKMAEW 649
W CS TCG+G Q+R + CR V + +E C+ + S R C +DC K
Sbjct: 1480 ANSWNECSVTCGSGVQQRDVYCRLKGVGQVVEEMCDQSTRPCSQRRCWSQDCVQHK--GM 1537
Query: 648 EECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPKGEEHIG 469
E C T ++ + + D + ++ + +++NCR PC
Sbjct: 1538 ERGRLNCSTSCERKDSHQRMECTDNQIRQVNEIVYNSSTISLTSKNCRNPPC-------- 1589
Query: 468 SWII--GDWSKCSASCGGGWXXXXXXXXXXXCDETRKPKMFDKCNEELCPPLTNN----- 310
++I+ D S+C+ +CG + + K + CP + ++
Sbjct: 1590 NYIVVTADSSQCANNCGFSYRQRITYCTEIPSTKKHKLHRLRPIVYQECPVVPSSQVYQC 1649
Query: 309 --------SWQISPWTHCSVSCGGGVQRRKIWCEDVLSGRKQDDIECSEIKPREQRDCEM 154
+W++ W+ CSV+CG G+ +R++ C + D+ + +KP Q+ C
Sbjct: 1650 INSCLHLATWKVGKWSKCSVTCGIGIMKRQVKC--ITKHGLSSDLCLNHLKPGAQKKCYA 1707
Query: 153 PPCRS 139
C+S
Sbjct: 1708 NDCKS 1712
Score = 248 bits (632), Expect = 1e-63
Identities = 179/675 (26%), Positives = 283/675 (41%), Gaps = 70/675 (10%)
Frame = -1
Query: 2232 WRVTDTWTECDRAC-RGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRW 2056
W ++ W+EC C +G + +++ C H D C + KP+ + C + W
Sbjct: 1026 WAASE-WSECLVTCGKGTKQRQVWCQLNVDHLS--DGFCNSSTKPESLSP-CELHTCASW 1081
Query: 2055 ITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYID-CSG-- 1885
C+ CG G + + V CV +E C S+PSD SC + CS
Sbjct: 1082 QVGPWGPCTTTCGHGYQMRDVKCVNELASAVLEDTE--CHEASRPSDRQSCVLTPCSFIS 1139
Query: 1884 ---------------RKWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQK 1750
+W +G WT CS +CG G R C D +R DES C +
Sbjct: 1140 KLETALLPTVLIKKMAQWRHGSWTPCSVSCG-RGTQARYVSCRDALDRIADESYCAHLPR 1198
Query: 1749 EATERECNRIPCPRWVYGHWSECSRSCDGGVKMRHAQCLD----------------AADR 1618
A +C PC W G WS CS SC G R C++ ++
Sbjct: 1199 PAEIWDCFT-PCGEWQAGDWSPCSASCGHGKTTRQVLCMNYHQPIDENYCDPEVRPLMEQ 1257
Query: 1617 ETHTSRCGPAQ--------------------TQE-HCNEHACTW-------WQFGVWSDC 1522
E + C PA TQ+ NE+ W+ G W C
Sbjct: 1258 ECSLAACPPAHSHFPSSPVQPSYYLSTNLPLTQKLEDNENQVVHPSVRGNQWRTGPWGSC 1317
Query: 1521 SAKCGDGVQYRDANCTDRH-RSVLPEHRCLKMEKIITKPCHRESCPKYKLGEWSQCSVSC 1345
S+ C G+Q+ C D + +S K ++ + C CP++ G W +CS +C
Sbjct: 1318 SSSCSGGLQHTAVVCQDENGQSASYCDAASKPPEL--QQCGPGPCPQWNYGNWGECSQTC 1375
Query: 1344 EDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPF---WRNTDWSACSVSC 1174
G SR V C NG ++ C + P+ Q C++ CP W W++CS SC
Sbjct: 1376 GGGIKSRLVICQFPNGQILEDHNCEIVNKPPSVIQ-CHMHACPADVSWHQEPWTSCSASC 1434
Query: 1173 GIGHRERTTECIYR-EQSVDASFCGDTKMPETSQTCHLLPCTSWKPSHWSPCSVTCGSGI 997
G G + R CI + ++ ++ + C + P T + C + C SWK + W+ CSVTCGSG+
Sbjct: 1435 GKGRKYREVFCIDQFQRKLEDTNCSQVQKPPTHKACRSVRCPSWKANSWNECSVTCGSGV 1494
Query: 996 QTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGP 817
Q R V C G +V+E CD++TRP ++ C C + +++ + +
Sbjct: 1495 QQRDVYCRLKGVGQVVEE-MCDQSTRPCSQRRCWSQDCVQHKGMERGRLN---------- 1543
Query: 816 WTACSATCGNGTQRRLLKCRDH-VRDLPDEYCNHLDKEVSTRNCRLRDCSYWKM-AEWEE 643
CS +C + ++C D+ +R + + N ++++NCR C+Y + A+ +
Sbjct: 1544 ---CSTSCERKDSHQRMECTDNQIRQVNEIVYNSSTISLTSKNCRNPPCNYIVVTADSSQ 1600
Query: 642 CPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPKGEEHIGSW 463
C CG +Q R C + L + V + + ++ C H+ +W
Sbjct: 1601 CANNCGFSYRQ-RITYCTEIPSTKKHKLHRLRPIVYQECPVVPSSQVYQCINSCLHLATW 1659
Query: 462 IIGDWSKCSASCGGG 418
+G WSKCS +CG G
Sbjct: 1660 KVGKWSKCSVTCGIG 1674
Score = 207 bits (528), Expect = 2e-51
Identities = 164/596 (27%), Positives = 247/596 (40%), Gaps = 58/596 (9%)
Frame = -1
Query: 2286 TAAVPNAVIRPISSALYLWRVTDTWTECDRAC-RGQQSQKLMCLDMSTHRQSHDRNCQNV 2110
TA +P +I+ ++ WR +WT C +C RG Q++ + C D + R + + C ++
Sbjct: 1143 TALLPTVLIKKMAQ----WR-HGSWTPCSVSCGRGTQARYVSCRD-ALDRIADESYCAHL 1196
Query: 2109 LKPKQATRMCNIDCST---RWITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLC 1939
+P + DC T W D S CSA CG G+ ++V C+ P E+ C
Sbjct: 1197 PRPAEIW-----DCFTPCGEWQAGDWSPCSASCGHGKTTRQVLCMNYH----QPIDENYC 1247
Query: 1938 DRNSKP-----SDIASC----------------YIDCS--------------------GR 1882
D +P +A+C Y+ + G
Sbjct: 1248 DPEVRPLMEQECSLAACPPAHSHFPSSPVQPSYYLSTNLPLTQKLEDNENQVVHPSVRGN 1307
Query: 1881 KWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWV 1702
+W G W SCS +C S G H C D++ + S C K ++C PCP+W
Sbjct: 1308 QWRTGPWGSCSSSC-SGGLQHTAVVCQDENGQSA--SYCDAASKPPELQQCGPGPCPQWN 1364
Query: 1701 YGHWSECSRSCDGGVKMRHAQCLDAADRETHTSRCG-----PAQTQEHCNEHAC---TWW 1546
YG+W ECS++C GG+K R C + C P+ Q C+ HAC W
Sbjct: 1365 YGNWGECSQTCGGGIKSRLVICQFPNGQILEDHNCEIVNKPPSVIQ--CHMHACPADVSW 1422
Query: 1545 QFGVWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIIT-KPCHRESCPKYKLGE 1369
W+ CSA CG G +YR+ C D+ + L + C +++K T K C CP +K
Sbjct: 1423 HQEPWTSCSASCGKGRKYREVFCIDQFQRKLEDTNCSQVQKPPTHKACRSVRCPSWKANS 1482
Query: 1368 WSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNTDWSA 1189
W++CSV+C G R V C +V +C S RP S + C C + +
Sbjct: 1483 WNECSVTCGSGVQQRDVYCRLKGVGQVVEEMCDQ-STRPCSQRRCWSQDCVQHKGMERGR 1541
Query: 1188 --CSVSCGIGHRERTTECIYRE-QSVDASFCGDTKMPETSQTCHLLPCTSWK-PSHWSPC 1021
CS SC + EC + + V+ + + TS+ C PC + S C
Sbjct: 1542 LNCSTSCERKDSHQRMECTDNQIRQVNEIVYNSSTISLTSKNCRNPPCNYIVVTADSSQC 1601
Query: 1020 SVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVP 841
+ CG + R CT E ++ R RP + + C +V Q + + +
Sbjct: 1602 ANNCGFSYRQRITYCT---EIPSTKKHKLHR-LRPIVYQECP--VVPSSQVYQCINSCLH 1655
Query: 840 PIRWATGPWTACSATCGNGTQRRLLKCRDHVRDLPDEYCNHLDKEVSTRNCRLRDC 673
W G W+ CS TCG G +R +KC D NHL K + + C DC
Sbjct: 1656 LATWKVGKWSKCSVTCGIGIMKRQVKCITKHGLSSDLCLNHL-KPGAQKKCYANDC 1710
Score = 145 bits (366), Expect = 1e-32
Identities = 108/422 (25%), Positives = 172/422 (40%), Gaps = 26/422 (6%)
Frame = -1
Query: 2232 WRVTDTWTECDRACRGQ-QSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRW 2056
WR T W C +C G Q ++C D + S+ C KP + + C +W
Sbjct: 1309 WR-TGPWGSCSSSCSGGLQHTAVVCQDENGQSASY---CDAASKPPEL-QQCGPGPCPQW 1363
Query: 2055 ITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYIDC--SGR 1882
+ CS CG G K + V C G +H C+ +KP + C++ +
Sbjct: 1364 NYGNWGECSQTCGGGIKSRLVICQFPNGQI---LEDHNCEIVNKPPSVIQCHMHACPADV 1420
Query: 1881 KWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWV 1702
W+ WTSCS +CG G+ +R+ +C+D R+++++ C + QK T + C + CP W
Sbjct: 1421 SWHQEPWTSCSASCGK-GRKYREVFCIDQFQRKLEDTNCSQVQKPPTHKACRSVRCPSWK 1479
Query: 1701 YGHWSECSRSCDGGVKMRHAQCLDAADRETHTSRCGPAQTQEHCNEHACTWWQFGVWS-- 1528
W+ECS +C GV+ R C + C Q+ C++ C W Q V
Sbjct: 1480 ANSWNECSVTCGSGVQQRDVYCRLKGVGQVVEEMCD--QSTRPCSQRRC-WSQDCVQHKG 1536
Query: 1527 ------DCSAKCGDGVQYRDANCTDRH-RSVLPEHRCLKMEKIITKPCHRESCPKYKL-G 1372
+CS C ++ CTD R V + +K C C +
Sbjct: 1537 MERGRLNCSTSCERKDSHQRMECTDNQIRQVNEIVYNSSTISLTSKNCRNPPCNYIVVTA 1596
Query: 1371 EWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCN----------LGT 1222
+ SQC+ +C + R C T+ RP +Q C + +
Sbjct: 1597 DSSQCANNCGFSYRQRITYCTEIPSTKKHK----LHRLRPIVYQECPVVPSSQVYQCINS 1652
Query: 1221 C---PFWRNTDWSACSVSCGIGHRERTTECIYREQSVDASFCGDTKMPETSQTCHLLPCT 1051
C W+ WS CSV+CGIG +R +CI + + + C + P + C+ C
Sbjct: 1653 CLHLATWKVGKWSKCSVTCGIGIMKRQVKCI-TKHGLSSDLCLNHLKPGAQKKCYANDCK 1711
Query: 1050 SW 1045
S+
Sbjct: 1712 SF 1713
>gi|29500537|gb|AAO74896.1| ADAMTS20 A short isoform [Mus musculus]
Length = 1425
Score = 922 bits (2382), Expect = 0.0
Identities = 513/1371 (37%), Positives = 700/1371 (50%), Gaps = 98/1371 (7%)
Frame = -1
Query: 4464 GGMSRTDPD---CIYRAHVKGVHQHSIV-NLCDSEDGLYGMLALPSGIHTVEPIISGNGT 4297
GG S PD C YR V H+ V +LC GL G G + +EP++ +G+
Sbjct: 117 GGRSTESPDLRHCFYRGQVNAREDHTAVFSLCG---GLMGTFKANDGEYFLEPVLRADGS 173
Query: 4296 EHDGASRHRQHLVRKFDPMHFKSFDHLNS---TSVNETETTVATWQ---------DQWED 4153
HD ++ HL+ + + + SF + S N+ E T Q D E+
Sbjct: 174 AHDD-DHNKPHLIYRQE-LKRNSFARSHKPCEVSENQMEKTALPSQSSRNTTGDVDIEEE 231
Query: 4152 VIERKARSRRAANS-------WDHYVEVLVVADTKMYEYHGRSLEDYVLTLFSTVASIYR 3994
+ R R +S + YVEV+V AD KM +HG++L+ YVLTL S VA+IY+
Sbjct: 232 AVFRLEGERSQLHSRNKRFLSYPRYVEVMVTADAKMVHHHGQNLQHYVLTLMSIVAAIYK 291
Query: 3993 HQSLRASXXXXXXXXXXXKTENAGPRITQNAQQTLQDFCRWQQYYNDPDDSSVQHHDVAI 3814
S+ +E GP I+ NA TL++FC WQQ N PDD+ HHD A+
Sbjct: 292 DSSIGNLINIVIVKLVVIHSEQEGPVISFNAATTLRNFCLWQQSQNVPDDAHPSHHDTAV 351
Query: 3813 LLTRKDICRSQGKCDTLGLAELGTMCDMQKSCAIIEDNGLSAAFTIAHELGHVFSIPHDD 3634
L+TR+DIC ++ KCDTLGLAELGT+CD +SC+I E+NGLSAAFTIAHELGHVF++PHDD
Sbjct: 352 LITREDICGAKEKCDTLGLAELGTLCDPSRSCSISEENGLSAAFTIAHELGHVFNVPHDD 411
Query: 3633 ERKCSTYMPVNKVCKFQSTKFDKTQFQNNFHIMAPTLEYNTHPWSWSPCSAGMLERFLEN 3454
KC + ++ +H+MAPTL Y+T PW+WS CS + FL+
Sbjct: 412 SFKCK-----------------EAGIKHQYHVMAPTLNYHTSPWTWSACSQKHITEFLDT 454
Query: 3453 NRGQTQCLFDQPVERRYYEDVFVRDEPGKKYDAHQQCKFVFGPASELCPYMPTCRRLWCA 3274
G +CL D+P R Y PG YD ++QC+ +FGP S++CPY+ CRRLWC
Sbjct: 455 GHG--ECLLDKPNGRTY---DLSPQLPGSVYDGNRQCELMFGPGSQVCPYLKHCRRLWCT 509
Query: 3273 TFYGSQMGCRTQHMPWADGTPCDESRSMFCHHGACVRLAPESLTKIDGQWGDWRSWGECS 3094
+ G GCRTQHMP ADGT C M CH G CV E+ +DG+WG W + CS
Sbjct: 510 SAEGVHKGCRTQHMPLADGTSC--GPGMHCHRGLCVTRDMET-RPVDGEWGPWGPYSSCS 566
Query: 3093 RTCGGGVQKGLRDCDSPKPRNGGKYCVGQRERYRSCNTQECPWDTQPYREVQCSEFNNKD 2914
RTCGGG++ R CD P+PRNGG+YCVG+R ++RSCNT CP + +RE QCS+F+ K
Sbjct: 567 RTCGGGIKSTARLCDRPEPRNGGRYCVGRRMKFRSCNTDSCPKGKRDFREKQCSDFDGKH 626
Query: 2913 IGIQGVASTNTHWVPKYANVAPNERCKLYCRLSGSAAFYLLRDKVVDGTPCDRNGDDICV 2734
I G+ N W+PKY+ +A +RCKLYCR++G+ +FY L+D+V DGTPC +DICV
Sbjct: 627 FDINGL-PPNVRWLPKYSGIAVKDRCKLYCRVAGTTSFYQLKDRVADGTPCGTETNDICV 685
Query: 2733 AGACMPAGCDHQLHSTLRRDKCGVCGGDDSSCKVVKGTFNEQGTFGYNEVMKIPAGSANI 2554
G C AGCDH L+S +RDKCGVCGGD+SSC+ + G FN +GYN V+KIPAG+ NI
Sbjct: 686 QGLCRQAGCDHVLNSKAKRDKCGVCGGDNSSCQTLAGVFN-SAHYGYNVVVKIPAGATNI 744
Query: 2553 DIRQKGYNNMKEDDNYLSLRAANGEFLLNGHFQVSLARQQIAFQDTVLEYSGSDAIIERI 2374
+I Q Y+ EDDNYL+L G FLLNG+F VS+A+++I Q V EYSGS+ IERI
Sbjct: 745 EILQHSYSGRPEDDNYLALSDTQGNFLLNGNFVVSMAKKEINIQGAVFEYSGSNNSIERI 804
Query: 2373 NGTGPIRSDIYVHVLSVGS-HPPDISYEYMTAAVPNAVIRPISSALYLWRVTDTWTECDR 2197
N T + +++ + VL VG+ + PD+ Y + N I S+ L+ W W +C +
Sbjct: 805 NSTDRLEAELVLQVLCVGNLYNPDVRYSF------NIPIEERSN-LFSWDPYGPWQDCTK 857
Query: 2196 ACRGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRWITEDVSSCSAKCG 2017
C+G +K+ C+ S H D NC ++ P T CN+DC RW S CS++CG
Sbjct: 858 MCQGLHRRKIACVRKSDHAVVSDHNCGHLPMPLFVTEKCNMDCELRWHIIGKSDCSSQCG 917
Query: 2016 SGQKRQRVSCVK--MEGDRQTPASEHLCDRNSKPSDIASCYIDCSGRKWNYGEWTSCSET 1843
G + V C+K + + P + C KP C+ C +W+Y EW+ CS +
Sbjct: 918 QGYRTLDVHCMKYSVHKGQAVPVGDQYCGDQLKPPSREPCHGSCVLTRWHYSEWSQCSRS 977
Query: 1842 CGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWVYGHWSECSRSCDG 1663
CG K R+SYCV+ R+ ES C RE CN PCP W WSEC +C
Sbjct: 978 CGGGDKT-RESYCVNGFGHRLAESEC-RELPRVVLENCNEFPCPSWATSEWSECPVTCGK 1035
Query: 1662 GVKMRHAQCLDAAD--RETHTSRCGPAQTQEHCNEHACTWWQFGVWSDCSAKCGDGVQYR 1489
G+K R C + D R+ + ++ C AC W G W C+A CG G Q R
Sbjct: 1036 GMKQRQVWCQLSEDPMRDGFCNASTKPESLRPCELRACASWHVGPWGSCTATCGHGYQMR 1095
Query: 1488 DANC-TDRHRSVLPEHRCLKMEKIITKPCHRESC------------------------PK 1384
C ++ ++L + C + ++P R+ C +
Sbjct: 1096 AVKCISEIFGTMLDDRECPQ----ASRPSDRQDCILAPCLAIPEVGATSLPAIPLGRAAQ 1151
Query: 1383 YKLGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRN 1204
++ G W+ CSVSC G +R VSC + D S C RPA+ C C W+
Sbjct: 1152 WRHGSWTPCSVSCGRGSQARYVSCRDAHDEVADESNCAHL-PRPAAVSLC-FSPCGEWQA 1209
Query: 1203 TDWSACSVSCGIGHRERTTECIYREQSVDASFCGDTKMPETSQTCHLLPC---------T 1051
WS CS SCG G R C+ Q VD S+C P T Q C L C +
Sbjct: 1210 GYWSPCSASCGHGKTTRRVLCVNYHQLVDESYCDPEGRPVTEQECSLAACPPLYSRAPSS 1269
Query: 1050 SWKPSH---------------------------------WSPCSVTCGSGIQTRSVSCTR 970
S +PSH W CS +C G+Q R+V C +
Sbjct: 1270 SEQPSHVPSRNVPLTHKPGENQDQGAQLSIRGNQWRTGPWGACSRSCAGGLQHRAVVC-Q 1328
Query: 969 GSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATCG 790
+G CD +++P + C C W G W C+ TCG
Sbjct: 1329 DEDGRSATS--CDGSSKPPESRHCGSGPCP---------------HWNYGDWGECTQTCG 1371
Query: 789 NGTQRRLLKCRDHVRDLPDEYCNHLDKEVSTRNCRLRDCS---YWKMAEWE 646
G + R + C+ + E+ L K S C L C W W+
Sbjct: 1372 GGVKSRFVICQFPNGQMTQEHSCELPKPPSMMQCHLHACPEDVSWYRGPWK 1422
Score = 253 bits (645), Expect = 4e-65
Identities = 167/578 (28%), Positives = 241/578 (40%), Gaps = 59/578 (10%)
Frame = -1
Query: 1701 YGHWSECSRSCDGGVKMRHAQCLDAADRETHTSR-CG----PAQTQEHCNEHACTWWQFG 1537
YG W +C++ C G + R C+ +D + CG P E CN W
Sbjct: 849 YGPWQDCTKMCQG-LHRRKIACVRKSDHAVVSDHNCGHLPMPLFVTEKCNMDCELRWHII 907
Query: 1536 VWSDCSAKCGDGVQYRDANCTDR--HRS----VLPEHRCLKMEKIITKPCHRESC--PKY 1381
SDCS++CG G + D +C H+ V ++ +++ +PCH SC ++
Sbjct: 908 GKSDCSSQCGQGYRTLDVHCMKYSVHKGQAVPVGDQYCGDQLKPPSREPCHG-SCVLTRW 966
Query: 1380 KLGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNT 1201
EWSQCS SC G +R CV+G G + S C + CN CP W +
Sbjct: 967 HYSEWSQCSRSCGGGDKTRESYCVNGFGHRLAESECRELPR--VVLENCNEFPCPSWATS 1024
Query: 1200 DWSACSVSCGIGHRERTTECIYREQSVDASFCGDTKMPETSQTCHLLPCTSWKPSHWSPC 1021
+WS C V+CG G ++R C E + FC + PE+ + C L C SW W C
Sbjct: 1025 EWSECPVTCGKGMKQRQVWCQLSEDPMRDGFCNASTKPESLRPCELRACASWHVGPWGSC 1084
Query: 1020 SVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDG-PRVLQKLQADV 844
+ TCG G Q R+V C GT++D+ C + +RP ++ C C P V +
Sbjct: 1085 TATCGHGYQMRAVKCISEIFGTMLDDRECPQASRPSDRQDCILAPCLAIPEVGATSLPAI 1144
Query: 843 P---PIRWATGPWTACSATCGNGTQRRLLKCRDHVRDLPDEY-CNHLDKEVSTRNCRLRD 676
P +W G WT CS +CG G+Q R + CRD ++ DE C HL + + C
Sbjct: 1145 PLGRAAQWRHGSWTPCSVSCGRGSQARYVSCRDAHDEVADESNCAHLPRPAAVSLC-FSP 1203
Query: 675 CSYWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEP 496
C W+ W C A+CG H + +R V CV+ ++ + CD + RP + + C L
Sbjct: 1204 CGEWQAGYWSPCSASCG-HGKTTRRVLCVNYHQ----LVDESYCDPEGRPVTEQECSLAA 1258
Query: 495 CP----------KGEEHIGS-------------------------WIIGDWSKCSASCGG 421
CP + H+ S W G W CS SC G
Sbjct: 1259 CPPLYSRAPSSSEQPSHVPSRNVPLTHKPGENQDQGAQLSIRGNQWRTGPWGACSRSCAG 1318
Query: 420 GWXXXXXX------XXXXXCDETRKPKMFDKCNEELCPPLTNNSWQISPWTHCSVSCGGG 259
G CD + KP C CP W W C+ +CGGG
Sbjct: 1319 GLQHRAVVCQDEDGRSATSCDGSSKPPESRHCGSGPCP-----HWNYGDWGECTQTCGGG 1373
Query: 258 VQRRKIWCEDVLSGRKQDDIECSEIKPREQRDCEMPPC 145
V+ R + C+ +G+ + C KP C + C
Sbjct: 1374 VKSRFVICQ-FPNGQMTQEHSCELPKPPSMMQCHLHAC 1410
Score = 180 bits (456), Expect = 4e-43
Identities = 129/441 (29%), Positives = 181/441 (40%), Gaps = 27/441 (6%)
Frame = -1
Query: 1374 GEWSQCSVSCEDGWSSRRVSCV-SGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNTD 1198
G W C+ C+ G R+++CV + V CG + CN+ W
Sbjct: 850 GPWQDCTKMCQ-GLHRRKIACVRKSDHAVVSDHNCGHLPMPLFVTEKCNMDCELRWHIIG 908
Query: 1197 WSACSVSCGIGHRERTTEC----IYREQSVDAS--FCGDTKMPETSQTCH-LLPCTSWKP 1039
S CS CG G+R C +++ Q+V +CGD P + + CH T W
Sbjct: 909 KSDCSSQCGQGYRTLDVHCMKYSVHKGQAVPVGDQYCGDQLKPPSREPCHGSCVLTRWHY 968
Query: 1038 SHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQK 859
S WS CS +CG G +TR C G + E + + PRV+ +
Sbjct: 969 SEWSQCSRSCGGGDKTRESYCVNGFG-----------------HRLAESECRELPRVVLE 1011
Query: 858 LQADVPPIRWATGPWTACSATCGNGTQRRLLKCRDHVRDLPDEYCNHLDKEVSTRNCRLR 679
+ P WAT W+ C TCG G ++R + C+ + D +CN K S R C LR
Sbjct: 1012 NCNEFPCPSWATSEWSECPVTCGKGMKQRQVWCQLSEDPMRDGFCNASTKPESLRPCELR 1071
Query: 678 DCSYWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLE 499
C+ W + W C ATCG H Q R V C+S G T+L D +C RP+ ++C L
Sbjct: 1072 ACASWHVGPWGSCTATCG-HGYQMRAVKCISEIFG--TMLDDRECPQASRPSDRQDCILA 1128
Query: 498 PC--------------PKGEEHIGSWIIGDWSKCSASCGGGWXXXXXX---XXXXXCDET 370
PC P G W G W+ CS SCG G DE+
Sbjct: 1129 PCLAIPEVGATSLPAIPLG--RAAQWRHGSWTPCSVSCGRGSQARYVSCRDAHDEVADES 1186
Query: 369 RKPKMFDKCNEELC-PPLTNNSWQISPWTHCSVSCGGGVQRRKIWCEDVLSGRKQDDIEC 193
+ LC P WQ W+ CS SCG G R++ C V + D+ C
Sbjct: 1187 NCAHLPRPAAVSLCFSPC--GEWQAGYWSPCSASCGHGKTTRRVLC--VNYHQLVDESYC 1242
Query: 192 S-EIKPREQRDCEMPPCRSHY 133
E +P +++C + C Y
Sbjct: 1243 DPEGRPVTEQECSLAACPPLY 1263
>gi|47219016|emb|CAG02054.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 2080
Score = 916 bits (2368), Expect = 0.0
Identities = 555/1693 (32%), Positives = 779/1693 (45%), Gaps = 262/1693 (15%)
Frame = -1
Query: 4437 CIYRAHVKGVHQHS-IVNLCDSEDGLYGMLALPSGIHTVEPIISGNGTEHD--------- 4288
C Y+ HV +H+ +++LC GL G P G + VEP+ + G ++
Sbjct: 114 CFYKGHVNAQGEHAAVISLCS---GLLGTFRSPEGEYFVEPLHNYQGEHYEEEHTKPHVV 170
Query: 4287 -----------GAS----------RHRQHLVRKFDPMH---------------FKSFDHL 4216
G S RHR+H ++ F + L
Sbjct: 171 YKKRAPKPQTSGESSACDTSGHQHRHRRHKPKRRQMPRAPPLPDTPPLVGARIFSDLESL 230
Query: 4215 NSTSVNETETTVATWQDQWEDVIERKARSRRAANSWDHYVEVLVVADTKMYEYHGRSLED 4036
++ V +E + + RS+R S+ +VEV++VAD+KM E+HG +L+
Sbjct: 231 SAGLVGASEGSPSGGPSNGSVDSGPHRRSKRFL-SYPRFVEVMLVADSKMVEHHGSNLQH 289
Query: 4035 YVLTLFS------------------TVASIYRHQSLRASXXXXXXXXXXXKTENAGPRIT 3910
Y+LTL S V+SIY+ S+ E GP I+
Sbjct: 290 YILTLMSIVSPKVNRPLQTGVLERLAVSSIYKDPSIGNLISIVVVKLVIINNELEGPVIS 349
Query: 3909 QNAQQTLQDFCRWQQYYNDPDDSSVQHHDVAILLTRKDICRSQGKCDTLG---------- 3760
NAQ TL++FC WQQ N DD+ HHD AIL+TR+DICR++ KCDTLG
Sbjct: 350 FNAQATLKNFCLWQQSQNVLDDNHHSHHDTAILITRQDICRARDKCDTLGERLDLEMTLV 409
Query: 3759 ----------------LAELGTMCDMQKSCAIIEDNGLSAAFTIAHELGHVFSIPHDDER 3628
LAELGT+CD +SC+IIEDNGLS AFTIAHELGHVF++PHDD
Sbjct: 410 IIFYCVIFLICFSGEGLAELGTVCDPYRSCSIIEDNGLSTAFTIAHELGHVFNMPHDDSN 469
Query: 3627 KCSTYMPVNKVCKFQSTKFDKTQFQNNFHIMAPTLEYNTHPWSWSPCSAGMLERFLENNR 3448
KC D + Q H+MAPTL YNT+PW WS CS + FL+
Sbjct: 470 KCQE---------------DGVKLQQ--HVMAPTLNYNTNPWMWSKCSRKYITEFLDTGY 512
Query: 3447 GQTQCLFDQPVERRYYEDVFVRDEPGKKYDAHQQCKFVFGPASELCPYMPTCRRLWCATF 3268
G+ CL D+P+ R Y + PG+ Y+ ++QC+ +FGP +++CPYM CRRLWC +
Sbjct: 513 GE--CLLDEPISRPY---TLPQQLPGQIYNVNKQCELIFGPGTQVCPYMMQCRRLWCTSP 567
Query: 3267 YGSQMGCRTQHMPWADGTPCDESRSMFCHHGACVRLAPESLTKIDGQWGDWRSWGECSRT 3088
G+Q GCRTQHMPWADGT C + C HG C+ ++ T +DG WG W +G CSRT
Sbjct: 568 EGAQRGCRTQHMPWADGTDCSPGKH--CKHGLCIAKDNDA-TPVDGTWGVWSPFGTCSRT 624
Query: 3087 CGGGVQKGLRDCDSPKPRNGGKYCVGQRERYRSCNTQECPWDTQPYREVQCSEFNNKDIG 2908
CGGG++ +R+C+ P PRNGGKYCVG+R ++RSCN++ C + +RE QC+ F+ +
Sbjct: 625 CGGGIKIAMRECNRPVPRNGGKYCVGRRMKFRSCNSEPCSKQKKDFREEQCAAFDGRHFN 684
Query: 2907 IQGVASTNTHWVPKYANVAPNERCKLYCRLSGSAAFYLLRDKVVDGTPCDRNGDDICVAG 2728
I G+ N WVPKY+ + +RCKL+CR++GS A+Y LRD+V+DGTPC + +DICV G
Sbjct: 685 INGLPP-NVRWVPKYSGILMKDRCKLFCRVAGSTAYYQLRDRVIDGTPCGPDTNDICVQG 743
Query: 2727 ACMPAGCDHQLHSTLRRDKCGVCGGDDSSCKVVKGTFNEQGTFGYNEVMKIPAGSANIDI 2548
C AGCDH L+S RRDKCGVCGGD+SSCK V GTFN +GYNEV++IP+G+ NID+
Sbjct: 744 LCRQAGCDHVLNSKARRDKCGVCGGDNSSCKTVAGTFNIV-HYGYNEVVRIPSGATNIDV 802
Query: 2547 RQKGYNNMKEDDNYLSLRAANGEFLLNGHFQVSLARQQIAFQDTVLEYSGSDAIIERING 2368
RQ Y+ +DDNYL++ + GEFLLNG F VS+ +++I + V+EYSGSD +IERIN
Sbjct: 803 RQHSYSGKPDDDNYLAISNSRGEFLLNGEFVVSMFKREIKVGNAVIEYSGSDHVIERINC 862
Query: 2367 TGPIRSDIYVHVLSVGS-HPPDISYEYMTAAVPNAVIRPISSALYLWRVTDTWTECDRAC 2191
T + +I + VLSVG + PD+ Y + N I + W W EC C
Sbjct: 863 TDRMEEEIVIQVLSVGKLYNPDVRYSF------NIPIED-KPQQFFWDAYGPWQECSSLC 915
Query: 2190 RGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCS------------------ 2065
+G + +K++C S D+ C + +P CN +C
Sbjct: 916 QGVRKRKILCSRESDRVVVSDQRCHGIPRPPVIADPCNTECELRFVSPVYCPNKRFLVLF 975
Query: 2064 -------------TRWITEDVSSCSAKCGSGQKRQRVSCVKM-EGDRQT-PASEHLCDRN 1930
+RW S C+A+CG G + + C K+ D +T + C
Sbjct: 976 LFFFFLISNLTSRSRWHVARKSECTAQCGLGYRTLEIYCAKISHADGKTEKVDDRFCSGQ 1035
Query: 1929 SKPSDIASCYIDCSGRKWNYGEWT--------------------------SCSETCGSNG 1828
KP + C+ DC+ W Y W+ CS++CG G
Sbjct: 1036 HKPDNKEVCHGDCNPGGWEYSPWSEVGGGNRRDCVRDCMLTLTDAGAFVLQCSKSCG-GG 1094
Query: 1827 KMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWVYGHWSECSRSCDGGVKMR 1648
R + C + DES C + K T + CN CP+W G WSEC +C G K R
Sbjct: 1095 SRRRGAVCRKAAEADGDESRCSQRDK-LTSQPCNEFLCPQWKTGDWSECLVTCGKGYKHR 1153
Query: 1647 HAQCLDAADRETHTSRCGPAQ--TQEHCNEHACTWWQFGVWSDCSAKCGDGVQYRDANC- 1477
C DR CG + + + C + C WQ G W C+ CG G Q R C
Sbjct: 1154 QTWCQFGEDR-LDDRLCGSPKPDSVQACQQQECASWQVGPWGQCTTSCGPGYQMRAVKCV 1212
Query: 1476 TDRHRSVLPEHRC-LKMEKIITKPCHRESCP-------------------KYKLGEWSQC 1357
+ +V+ + C T+ C CP +++ G W+QC
Sbjct: 1213 VGPYGAVMDDTECNAATRPTETQDCELAQCPSSHPVPPGIKVLSHHGHKTQWRFGSWTQC 1272
Query: 1356 SVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNTDWSACSVS 1177
S SC G R VSC G D S C +P + + C++ C W+ +W+ACSV+
Sbjct: 1273 SASCGKGTRMRYVSCRDNQGGVADESACAHL-PKPPAREMCSVVACGQWKVLEWTACSVT 1331
Query: 1176 CGIGHRERTTECI-YREQSVDASFCGDTKMPETSQTCHLLPCTS---------------- 1048
CG G R C+ + +Q V+AS C P T Q C + C S
Sbjct: 1332 CGQGTTTRQVLCVNFSDQEVNASECDPDDRPATEQDCAMSQCPSRSSEPRPFPSSPNTSA 1391
Query: 1047 -----------WKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKT 901
W+ W CS TC G Q R V C + G C+ +RP +++
Sbjct: 1392 RNNLPHSESHQWRTGPWGACSSTCAGGFQRRVVVC-QDENGYPASS--CEDRSRPNEQRS 1448
Query: 900 CEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATCGNGTQRRLLKC-RDHVRDLPDEYC 724
CE C +W G W C+ CG G + RL+ C R + D C
Sbjct: 1449 CESGPCP---------------QWIYGNWGECTKPCGGGIKTRLVVCQRPNGERFNDLSC 1493
Query: 723 NHLDKEVSTRNCRLRDC---SYWKMAEW-------------------------------- 649
DK C + C +W W
Sbjct: 1494 EIHDKPPDREQCNTQPCPSSPHWSADPWSSITILLWTVKADPESVLRGCSPPSRLLLVIN 1553
Query: 648 ---------------EECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCD-VQKRPTSA 517
++C A+CG + R V+C++A ++ + +C + P+
Sbjct: 1554 VCTDITPYFKGLLTQQQCSASCGRGF-RVRKVSCLAASG---LVISEENCQGLSLEPSRR 1609
Query: 516 RNCRLEPCPKGEEHIGSWIIGDWSKCSASCGGG--------WXXXXXXXXXXXCDETRKP 361
R CR CPK W +W +CSASCG G C + +P
Sbjct: 1610 RRCRGGRCPK-------WKTSNWGECSASCGDGVQQREVFCQAGDQRLPEESGCSQRSRP 1662
Query: 360 KMFDKCNEELCPPLTNNSWQISPWTHCSVSCGGGVQRRKIWCEDVLSGRKQDDIECSE-I 184
C CP + W+ W CS SCGGG +RR + CED R+ ++ C+ I
Sbjct: 1663 PTSQSCGNAACP--SRYRWREGDWQTCSKSCGGGHRRRALQCED-HDRREFHEMYCANLI 1719
Query: 183 KPREQRDCEMPPC 145
+P + C C
Sbjct: 1720 RPPDVESCNSQAC 1732
Score = 231 bits (589), Expect = 1e-58
Identities = 193/839 (23%), Positives = 295/839 (35%), Gaps = 151/839 (17%)
Frame = -1
Query: 2208 ECDRACRGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRWITEDVSSCS 2029
+C ++C G ++ + + C + K ++ CN +W T D S C
Sbjct: 1086 QCSKSCGGGSRRRGAVCRKAAEADGDESRCSQ--RDKLTSQPCNEFLCPQWKTGDWSECL 1143
Query: 2028 AKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYI-DCSGRKWNYGEWTSC 1852
CG G K ++ C E DR + LC + KP + +C +C+ W G W C
Sbjct: 1144 VTCGKGYKHRQTWCQFGE-DR---LDDRLCG-SPKPDSVQACQQQECAS--WQVGPWGQC 1196
Query: 1851 SETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCP------------- 1711
+ +CG +M V +D++ C + ++C CP
Sbjct: 1197 TTSCGPGYQMRAVKCVVGPYGAVMDDTECNAATRPTETQDCELAQCPSSHPVPPGIKVLS 1256
Query: 1710 ------RWVYGHWSECSRSCDGGVKMRHAQCLDAADRETHTSRCG---PAQTQEHCNEHA 1558
+W +G W++CS SC G +MR+ C D S C +E C+ A
Sbjct: 1257 HHGHKTQWRFGSWTQCSASCGKGTRMRYVSCRDNQGGVADESACAHLPKPPAREMCSVVA 1316
Query: 1557 CTWWQFGVWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIITKP-CHRESCP-- 1387
C W+ W+ CS CG G R C + + C ++ T+ C CP
Sbjct: 1317 CGQWKVLEWTACSVTCGQGTTTRQVLCVNFSDQEVNASECDPDDRPATEQDCAMSQCPSR 1376
Query: 1386 -------------------------KYKLGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDM 1282
+++ G W CS +C G+ R V C NG
Sbjct: 1377 SSEPRPFPSSPNTSARNNLPHSESHQWRTGPWGACSSTCAGGFQRRVVVCQDENGYPA-- 1434
Query: 1281 SLCGTASDRPASHQTCNLGTCPFWRNTDWSACSVSCGIGHRERTTECIYR--EQSVDASF 1108
S C S RP ++C G CP W +W C+ CG G + R C E+ D S
Sbjct: 1435 SSCEDRS-RPNEQRSCESGPCPQWIYGNWGECTKPCGGGIKTRLVVCQRPNGERFNDLS- 1492
Query: 1107 CGDTKMPETSQTCHLLPCTS---WKPSHWSP----------------------------- 1024
C P + C+ PC S W WS
Sbjct: 1493 CEIHDKPPDREQCNTQPCPSSPHWSADPWSSITILLWTVKADPESVLRGCSPPSRLLLVI 1552
Query: 1023 ------------------CSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDR-NTRPRLKKT 901
CS +CG G + R VSC S G ++ E C + P ++
Sbjct: 1553 NVCTDITPYFKGLLTQQQCSASCGRGFRVRKVSCLAAS-GLVISEENCQGLSLEPSRRRR 1611
Query: 900 CEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATCGNGTQRRLLKCRDHVRDLPDEY-C 724
C C +W T W CSA+CG+G Q+R + C+ + LP+E C
Sbjct: 1612 CRGGRCP---------------KWKTSNWGECSASCGDGVQQREVFCQAGDQRLPEESGC 1656
Query: 723 NHLDKEVSTRNCRLRDCSY---WKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKD 553
+ + ++++C C W+ +W+ C +CG + R + C ED R +
Sbjct: 1657 SQRSRPPTSQSCGNAACPSRYRWREGDWQTCSKSCGGG-HRRRALQC---EDHDRREFHE 1712
Query: 552 VDCDVQKRPTSARNCRLEPCPKGEEHIGSWIIGDWSK----------------------- 442
+ C RP +C + C WI G+W++
Sbjct: 1713 MYCANLIRPPDVESCNSQACEV------VWITGEWTEVTGERTHTSAALCLEPTRHITLV 1766
Query: 441 ------CSASCGGGWXXXXXXXXXXXCDETR--------------KPKMFDKCNEELCPP 322
CS SCG G+ + P+ + C+ + CP
Sbjct: 1767 TSAPLQCSGSCGQGYRRRLVSCSQVLVEGENYEYGHQSLSNCPGTPPESYMPCHLDPCPS 1826
Query: 321 LTNNSWQISPWTHCSVSCGGGVQRRKIWCEDVLSGRKQDDIECSEIKPREQRDCEMPPC 145
W++ W CS SCG GV R + C G +DD KP ++ C P C
Sbjct: 1827 -PQAWWRVGIWGPCSASCGEGVMERVVQCLADGQGCPEDD------KPEARKVCRNPSC 1878
Score = 227 bits (579), Expect = 2e-57
Identities = 170/644 (26%), Positives = 264/644 (40%), Gaps = 64/644 (9%)
Frame = -1
Query: 2232 WRVTDTWTECDRAC-RGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRW 2056
WR +WT+C +C +G + + + C D + + + C ++ KP A MC++ +W
Sbjct: 1264 WRF-GSWTQCSASCGKGTRMRYVSCRD-NQGGVADESACAHLPKPP-AREMCSVVACGQW 1320
Query: 2055 ITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYID-CSGR- 1882
+ ++CS CG G ++V CV D++ ASE CD + +P+ C + C R
Sbjct: 1321 KVLEWTACSVTCGQGTTTRQVLCVNFS-DQEVNASE--CDPDDRPATEQDCAMSQCPSRS 1377
Query: 1881 ------------------------KWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDE 1774
+W G W +CS TC + G R C D++
Sbjct: 1378 SEPRPFPSSPNTSARNNLPHSESHQWRTGPWGACSSTC-AGGFQRRVVVCQDENG--YPA 1434
Query: 1773 SLCGREQKEATERECNRIPCPRWVYGHWSECSRSCDGGVKMRHAQCLDAADRETHTSRC- 1597
S C + +R C PCP+W+YG+W EC++ C GG+K R C + C
Sbjct: 1435 SSCEDRSRPNEQRSCESGPCPQWIYGNWGECTKPCGGGIKTRLVVCQRPNGERFNDLSCE 1494
Query: 1596 --GPAQTQEHCNEHACT---WWQFGVWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLK 1432
+E CN C W WS + + A+ R P R L
Sbjct: 1495 IHDKPPDREQCNTQPCPSSPHWSADPWSSITIL----LWTVKADPESVLRGCSPPSRLLL 1550
Query: 1431 MEKIITKPCHRESCPKYK-LGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDR 1255
+ + T + P +K L QCS SC G+ R+VSC++ +G + C S
Sbjct: 1551 VINVCT-----DITPYFKGLLTQQQCSASCGRGFRVRKVSCLAASGLVISEENCQGLSLE 1605
Query: 1254 PASHQTCNLGTCPFWRNTDWSACSVSCGIGHRERTTECIYREQSV-DASFCGDTKMPETS 1078
P+ + C G CP W+ ++W CS SCG G ++R C +Q + + S C P TS
Sbjct: 1606 PSRRRRCRGGRCPKWKTSNWGECSASCGDGVQQREVFCQAGDQRLPEESGCSQRSRPPTS 1665
Query: 1077 QTCHLLPCTS---WKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLK 907
Q+C C S W+ W CS +CG G + R++ C + E +C RP
Sbjct: 1666 QSCGNAACPSRYRWREGDWQTCSKSCGGGHRRRALQC-EDHDRREFHEMYCANLIRPPDV 1724
Query: 906 KTCEKDTCD------------GPRVLQKLQADVPPIRWATGPWTA---CSATCGNGTQRR 772
++C C+ G R + P R T +A CS +CG G +RR
Sbjct: 1725 ESCNSQACEVVWITGEWTEVTGERTHTSAALCLEPTRHITLVTSAPLQCSGSCGQGYRRR 1784
Query: 771 LLKCRDHVRDLPDEYCNHLD-------KEVSTRNCRLRDC----SYWKMAEWEECPATCG 625
L+ C + + + H S C L C ++W++ W C A+CG
Sbjct: 1785 LVSCSQVLVEGENYEYGHQSLSNCPGTPPESYMPCHLDPCPSPQAWWRVGIWGPCSASCG 1844
Query: 624 THVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPC 493
V + R V C++ G C +P + + CR C
Sbjct: 1845 EGVME-RVVQCLADGQG---------CPEDDKPEARKVCRNPSC 1878
Score = 166 bits (421), Expect = 4e-39
Identities = 132/524 (25%), Positives = 202/524 (38%), Gaps = 53/524 (10%)
Frame = -1
Query: 1551 WWQFGVWSDCSAKCGDGVQYRDANCT-DRHRSVLPEHRC--LKMEKIITKPCHRESCPKY 1381
W +G W +CS+ C GV+ R C+ + R V+ + RC + +I PC+ E
Sbjct: 902 WDAYGPWQECSSLC-QGVRKRKILCSRESDRVVVSDQRCHGIPRPPVIADPCNTE----- 955
Query: 1380 KLGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNT 1201
CE + S V C + + + S NL + W
Sbjct: 956 -----------CELRFVSP-VYCPNKRFLVLFLFFFFLIS---------NLTSRSRWHVA 994
Query: 1200 DWSACSVSCGIGHRERTTECIY------REQSVDASFCGDTKMPETSQTCHLLPCT--SW 1045
S C+ CG+G+R C + + VD FC P+ + CH C W
Sbjct: 995 RKSECTAQCGLGYRTLEIYCAKISHADGKTEKVDDRFCSGQHKPDNKEVCHG-DCNPGGW 1053
Query: 1044 KPSHWSP--------------------------CSVTCGSGIQTRSVSCTRGSEGTIVDE 943
+ S WS CS +CG G + R C + +E DE
Sbjct: 1054 EYSPWSEVGGGNRRDCVRDCMLTLTDAGAFVLQCSKSCGGGSRRRGAVCRKAAEAD-GDE 1112
Query: 942 YFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATCGNGTQRRLLK 763
C + + + C + C +W TG W+ C TCG G + R
Sbjct: 1113 SRCSQRDK-LTSQPCNEFLCP---------------QWKTGDWSECLVTCGKGYKHRQTW 1156
Query: 762 CRDHVRDLPDEYCNHLDKEVSTRNCRLRDCSYWKMAEWEECPATCGTHVQQSRNVTCVSA 583
C+ L D C K S + C+ ++C+ W++ W +C +CG Q R V CV
Sbjct: 1157 CQFGEDRLDDRLCGS-PKPDSVQACQQQECASWQVGPWGQCTTSCGPGYQM-RAVKCVVG 1214
Query: 582 EDGGRTILKDVDCDVQKRPTSARNCRLEPCPKGEE------------HIGSWIIGDWSKC 439
G ++ D +C+ RPT ++C L CP H W G W++C
Sbjct: 1215 PYGA--VMDDTECNAATRPTETQDCELAQCPSSHPVPPGIKVLSHHGHKTQWRFGSWTQC 1272
Query: 438 SASCGGGWXXXXXX---XXXXXCDETRKPKMFDKCNEELCPPLTNNSWQISPWTHCSVSC 268
SASCG G DE+ + E+C + W++ WT CSV+C
Sbjct: 1273 SASCGKGTRMRYVSCRDNQGGVADESACAHLPKPPAREMCSVVACGQWKVLEWTACSVTC 1332
Query: 267 GGGVQRRKIWCEDVLSGRKQDDIECS-EIKPREQRDCEMPPCRS 139
G G R++ C + S ++ + EC + +P ++DC M C S
Sbjct: 1333 GQGTTTRQVLCVN-FSDQEVNASECDPDDRPATEQDCAMSQCPS 1375
Score = 98.2 bits (243), Expect = 2e-18
Identities = 86/347 (24%), Positives = 125/347 (35%), Gaps = 47/347 (13%)
Frame = -1
Query: 1032 WSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPR-LKKTCEKDT---------C 883
W CS C G++ R + C+R S+ +V + C RP + C + C
Sbjct: 908 WQECSSLC-QGVRKRKILCSRESDRVVVSDQRCHGIPRPPVIADPCNTECELRFVSPVYC 966
Query: 882 DGPRVLQK-------LQADVPPIRWATGPWTACSATCGNGTQRRLLKCRD------HVRD 742
R L + RW + C+A CG G + + C
Sbjct: 967 PNKRFLVLFLFFFFLISNLTSRSRWHVARKSECTAQCGLGYRTLEIYCAKISHADGKTEK 1026
Query: 741 LPDEYCNHLDKEVSTRNCRLRDCSY--WKMAEWEE--------CPATC-------GTHVQ 613
+ D +C+ K + C DC+ W+ + W E C C G V
Sbjct: 1027 VDDRFCSGQHKPDNKEVCH-GDCNPGGWEYSPWSEVGGGNRRDCVRDCMLTLTDAGAFVL 1085
Query: 612 QSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPKGEEHIGSWIIGDWSKCSA 433
Q + G K + D + S R+ +L P E W GDWS+C
Sbjct: 1086 QCSKSCGGGSRRRGAVCRKAAEADGDESRCSQRD-KLTSQPCNEFLCPQWKTGDWSECLV 1144
Query: 432 SCGGG------WXXXXXXXXXXXCDETRKPKMFDKCNEELCPPLTNNSWQISPWTHCSVS 271
+CG G W + KP C ++ C SWQ+ PW C+ S
Sbjct: 1145 TCGKGYKHRQTWCQFGEDRLDDRLCGSPKPDSVQACQQQECA-----SWQVGPWGQCTTS 1199
Query: 270 CGGGVQRRKIWCEDVLSGRKQDDIEC-SEIKPREQRDCEMPPCRSHY 133
CG G Q R + C G DD EC + +P E +DCE+ C S +
Sbjct: 1200 CGPGYQMRAVKCVVGPYGAVMDDTECNAATRPTETQDCELAQCPSSH 1246
>gi|28460690|ref|NP_079279.2| a disintegrin-like and metalloprotease
(reprolysin type) with thrombospondin type 1 motif, 20
isoform 1; a disintegrin-like and metalloprotease with
thrombospondin type 1 motifs 20 [Homo sapiens]
gi|28316229|emb|CAD56159.3| ADAMTS-20 protein [Homo sapiens]
Length = 1908
Score = 911 bits (2355), Expect = 0.0
Identities = 519/1544 (33%), Positives = 745/1544 (47%), Gaps = 113/1544 (7%)
Frame = -1
Query: 4437 CIYRAHVKGVHQH-SIVNLCDSEDGLYGMLALPSGIHTVEPIISGNGTEHDGASRHRQHL 4261
C YR V + ++V+LC GL G +G + +EPI+ +G E++ ++ HL
Sbjct: 129 CFYRGQVNSQEDYKAVVSLCG---GLVGTFKGQNGEYFLEPIMKADGNEYEDG-HNKPHL 184
Query: 4260 VRKFDP----MHFKSFDHLNSTSVNETETTVATWQDQWEDVI------------------ 4147
+ + D + + ++ + + ET T+ + ED+
Sbjct: 185 IYRQDLNNSFLQTLKYCSVSESQIKETSLPFHTYSNMNEDLNVMKERVLGHTSKNVPLKD 244
Query: 4146 ERKARSRRAANSWDHYVEVLVVADTKMYEYHGRSLEDYVLTLFSTVASIYRHQSLRASXX 3967
ER+ ++ S+ Y+E++V AD K+ HG +L++Y+LTL S VA+IY+ S+
Sbjct: 245 ERRHSRKKRLISYPRYIEIMVTADAKVVSAHGSNLQNYILTLMSIVATIYKDPSIGNLIH 304
Query: 3966 XXXXXXXXXKTENAGPRITQNAQQTLQDFCRWQQYYNDPDDSSVQHHDVAILLTRKDICR 3787
E GP I + TL++FC WQQ ND DD HHD A+L+TR DIC
Sbjct: 305 IVVVKLVMIHREEEGPVINFDGATTLKNFCSWQQTQNDLDDVHPSHHDTAVLITRYDICS 364
Query: 3786 SQGKCDTLGLAELGTMCDMQKSCAIIEDNGLSAAFTIAHELGHVFSIPHDDERKCSTYMP 3607
S+ KC+ LGL+ LGT+CD +SC I E+ GL +AFTIAHELGH + HDD +C M
Sbjct: 365 SKEKCNMLGLSYLGTICDPLQSCFINEEKGLISAFTIAHELGHTLGVQHDDNPRCKE-MK 423
Query: 3606 VNKVCKFQSTKFDKTQFQNNFHIMAPTLEYNTHPWSWSPCSAGMLERFLENNRGQTQCLF 3427
V K +H+MAP L ++ PWSWS CS + FLE G+ CL
Sbjct: 424 VTK-----------------YHVMAPALSFHMSPWSWSNCSRKYVTEFLETGYGE--CLL 464
Query: 3426 DQPVERRYYEDVFVRDEPGKKYDAHQQCKFVFGPASELCPYMPTCRRLWCATFYGSQMGC 3247
D+P E Y + PG +YD ++QC+ FGP S++CP++ C LWC + GC
Sbjct: 465 DKPDEEIYN---LPSELPGSRYDGNKQCELAFGPGSQMCPHINICMHLWCTSTEKLHKGC 521
Query: 3246 RTQHMPWADGTPCDESRSMFCHHGACVRLAPESLTKIDGQWGDWRSWGECSRTCGGGVQK 3067
TQH+P ADGT C M C HG CV E+ ++G+WG W + CSRTCGGG++
Sbjct: 522 FTQHVPPADGTDCGPG--MHCRHGLCVNKETET-RPVNGEWGPWEPYSSCSRTCGGGIES 578
Query: 3066 GLRDCDSPKPRNGGKYCVGQRERYRSCNTQECPWDTQPYREVQCSEFNNKDIGIQGVAST 2887
R C+ P+PRNGG YCVG+R ++RSCNT CP TQ +RE QCS+FN K + I G+ S
Sbjct: 579 ATRRCNRPEPRNGGNYCVGRRMKFRSCNTDSCPKGTQDFREKQCSDFNGKHLDISGIPS- 637
Query: 2886 NTHWVPKYANVAPNERCKLYCRLSGSAAFYLLRDKVVDGTPCDRNGDDICVAGACMPAGC 2707
N W+P+Y+ V +RCKLYC+++G+ FYLL+D V DGTPC DICV G CM AGC
Sbjct: 638 NVRWLPRYSGVGTKDRCKLYCQVAGTNYFYLLKDMVEDGTPCGTETHDICVQGQCMAAGC 697
Query: 2706 DHQLHSTLRRDKCGVCGGDDSSCKVVKGTFNEQGTFGYNEVMKIPAGSANIDIRQKGYNN 2527
DH L+S+ + DKCGVCGGD+SSCK + G FN +GYN V+KIPAG+ N+DIRQ Y+
Sbjct: 698 DHVLNSSAKIDKCGVCGGDNSSCKTITGVFN-SSHYGYNVVVKIPAGATNVDIRQYSYSG 756
Query: 2526 MKEDDNYLSLRAANGEFLLNGHFQVSLARQQIAFQDTVLEYSGSDAIIERINGTGPIRSD 2347
+ DD+YL+L A G FL NG+F +S ++++I Q TV+EYSGS+ +ERIN T +
Sbjct: 757 -QPDDSYLALSDAEGNFLFNGNFLLSTSKKEINVQGTVIEYSGSNNAVERINSTNRQEKE 815
Query: 2346 IYVHVLSVGS-HPPDISYEYMTAAVPNAVIRPISSALYLWRVTDTWTECDRACRGQQSQK 2170
I + VL VG+ + PD+ Y + N + S ++ W W C + C+G Q +
Sbjct: 816 ILIEVLCVGNLYNPDVHYSF------NIPLEE-RSDMFTWDPYGPWEGCTKMCQGLQRRN 868
Query: 2169 LMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRWITEDVSSCSAKCGSGQKRQRVS 1990
+ C+ S H D+ C ++ P T+ CN DC RW S CS++CG G + +
Sbjct: 869 ITCIHKSDHSVVSDKECDHLPLPSFVTQSCNTDCELRWHVIGKSECSSQCGQGYRTLDIH 928
Query: 1989 CVK--MEGDRQTPASEHLCDRNSKPSDIASCYIDCSGRKWNYGEWTSCSETCGSNGKMHR 1816
C+K + + +H C KP C+ +C +W+Y EW+ CS +CG G+ R
Sbjct: 929 CMKYSIHEGQTVQVDDHYCGDQLKPPTQELCHGNCVFTRWHYSEWSQCSRSCG-GGERSR 987
Query: 1815 KSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWVYGHWSECSRSCDGGVKMRHAQC 1636
+SYC+++ R+ ++ C +E T CN CP W WSEC +C G K R C
Sbjct: 988 ESYCMNNFGHRLADNEC-QELSRVTRENCNEFSCPSWAASEWSECLVTCGKGTKQRQVWC 1046
Query: 1635 LDAADR--ETHTSRCGPAQTQEHCNEHACTWWQFGVWSDCSAKCGDGVQYRDANCTDRHR 1462
D + + ++ C H C WQ G W C+ CG G Q RD C +
Sbjct: 1047 QLNVDHLSDGFCNSSTKPESLSPCELHTCASWQVGPWGPCTTTCGHGYQMRDVKCVNELA 1106
Query: 1461 S-VLPEHRCLKMEKIITKPCHRESC------------------------PKYKLGEWSQC 1357
S VL + C + ++P R+SC +++ G W+ C
Sbjct: 1107 SAVLEDTECHE----ASRPSDRQSCVLTPCSFISKLETALLPTVLIKKMAQWRHGSWTPC 1162
Query: 1356 SVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNTDWSACSVS 1177
SVSC G +R VSC D S C RPA C C W+ DWS CS S
Sbjct: 1163 SVSCGRGTQARYVSCRDALDRIADESYCAHL-PRPAEIWDC-FTPCGEWQAGDWSPCSAS 1220
Query: 1176 CGIGHRERTTECIYREQSVDASFCGDTKMPETSQTCHLLPC------------------- 1054
CG G R C+ Q +D ++C P Q C L C
Sbjct: 1221 CGHGKTTRQVLCMNYHQPIDENYCDPEVRPLMEQECSLAACPPAHSHFPSSPVQPSYYLS 1280
Query: 1053 -----------------------TSWKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDE 943
W+ W CS +C G+Q R+V C + G
Sbjct: 1281 TNLPLTQKLEDNENQVVHPSVRGNQWRTGPWGQCSSSCSGGLQHRAVVC-QDENGQSAS- 1338
Query: 942 YFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATCGNGTQRRLLK 763
+CD ++P + C C +W G W CS TCG G + RL+
Sbjct: 1339 -YCDAASKPPELQQCGPGPCP---------------QWNYGNWGECSQTCGGGIKSRLVI 1382
Query: 762 CR-DHVRDLPDEYCNHLDKEVSTRNCRLRDCS---YWKMAEWEECPATCGTHVQQSRNVT 595
C+ + + L D C ++K S C + C W W C A+CG ++ R V
Sbjct: 1383 CQFPNGQILEDHNCEIVNKPPSVIQCHMHACPADVSWHQEPWTSCSASCGKG-RKYREVF 1441
Query: 594 CVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPKGEEHIGSWIIGDWSKCSASCGGGW 415
C+ D + L+D +C ++P + + CR CP SW W++CS +CG G
Sbjct: 1442 CI---DQFQRKLEDTNCSQVQKPPTHKACRSVRCP-------SWKANSWNECSVTCGSG- 1490
Query: 414 XXXXXXXXXXXCDETRKPKMFDKCNEELCPPLTNNSWQISPWT--------------HCS 277
D + K + EE+C T Q W+ +CS
Sbjct: 1491 --------VQQRDVYCRLKGVGQVVEEMCDQSTRPCSQRRCWSQDCVQHKGMERGRLNCS 1542
Query: 276 VSCGGGVQRRKIWCEDVLSGRKQDDIECSEIKPREQRDCEMPPC 145
SC +++ C D + + + S ++C PPC
Sbjct: 1543 TSCERKDSHQRMECTDNQIRQVNEIVYNSSTISLTSKNCRNPPC 1586
Score = 270 bits (690), Expect = 3e-70
Identities = 192/785 (24%), Positives = 315/785 (39%), Gaps = 87/785 (11%)
Frame = -1
Query: 2232 WRVTDTWTECDRACRG-QQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRW 2056
W ++ W++C R+C G ++S++ C++ HR + D CQ + + + CN W
Sbjct: 968 WHYSE-WSQCSRSCGGGERSRESYCMNNFGHRLA-DNECQELSRVTREN--CNEFSCPSW 1023
Query: 2055 ITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYIDCSGRKW 1876
+ S C CG G K+++V C ++ D S+ C+ ++KP ++ C + W
Sbjct: 1024 AASEWSECLVTCGKGTKQRQVWC-QLNVDH---LSDGFCNSSTKPESLSPCELHTCA-SW 1078
Query: 1875 NYGEWTSCSETCGSNGKMHRKSYCVDD-SNRRVDESLCGREQKEATERECNRIPCP---- 1711
G W C+ TCG +G R CV++ ++ ++++ C + + + C PC
Sbjct: 1079 QVGPWGPCTTTCG-HGYQMRDVKCVNELASAVLEDTECHEASRPSDRQSCVLTPCSFISK 1137
Query: 1710 ---------------RWVYGHWSECSRSCDGGVKMRHAQCLDAADRETHTSRCG----PA 1588
+W +G W+ CS SC G + R+ C DA DR S C PA
Sbjct: 1138 LETALLPTVLIKKMAQWRHGSWTPCSVSCGRGTQARYVSCRDALDRIADESYCAHLPRPA 1197
Query: 1587 QTQEHCNEHACTWWQFGVWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIITKP 1408
+ + C WQ G WS CSA CG G R C + H+ + + ++ ++ +
Sbjct: 1198 EIWDCFTP--CGEWQAGDWSPCSASCGHGKTTRQVLCMNYHQPIDENYCDPEVRPLMEQE 1255
Query: 1407 CHRESCP------------------------------------------KYKLGEWSQCS 1354
C +CP +++ G W QCS
Sbjct: 1256 CSLAACPPAHSHFPSSPVQPSYYLSTNLPLTQKLEDNENQVVHPSVRGNQWRTGPWGQCS 1315
Query: 1353 VSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNTDWSACSVSC 1174
SC G R V C NG S C AS +P Q C G CP W +W CS +C
Sbjct: 1316 SSCSGGLQHRAVVCQDENGQSA--SYCDAAS-KPPELQQCGPGPCPQWNYGNWGECSQTC 1372
Query: 1173 GIGHRERTTECIYRE-QSVDASFCGDTKMPETSQTCHLLPC---TSWKPSHWSPCSVTCG 1006
G G + R C + Q ++ C P + CH+ C SW W+ CS +CG
Sbjct: 1373 GGGIKSRLVICQFPNGQILEDHNCEIVNKPPSVIQCHMHACPADVSWHQEPWTSCSASCG 1432
Query: 1005 SGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWA 826
G + R V C + + D C + +P K C C W
Sbjct: 1433 KGRKYREVFCIDQFQRKLEDTN-CSQVQKPPTHKACRSVRCPS---------------WK 1476
Query: 825 TGPWTACSATCGNGTQRRLLKCR-DHVRDLPDEYCNHLDKEVSTRNCRLRDCSYWKMAEW 649
W CS TCG+G Q+R + CR V + +E C+ + S R C +DC K
Sbjct: 1477 ANSWNECSVTCGSGVQQRDVYCRLKGVGQVVEEMCDQSTRPCSQRRCWSQDCVQHK--GM 1534
Query: 648 EECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPKGEEHIG 469
E C T ++ + + D + ++ + +++NCR PC
Sbjct: 1535 ERGRLNCSTSCERKDSHQRMECTDNQIRQVNEIVYNSSTISLTSKNCRNPPC-------- 1586
Query: 468 SWII--GDWSKCSASCGGGWXXXXXXXXXXXCDETRKPKMFDKCNEELCPPLTNN----- 310
++I+ D S+C+ +CG + + K + CP + ++
Sbjct: 1587 NYIVVTADSSQCANNCGFSYRQRITYCTEIPSTKKHKLHRLRPIVYQECPVVPSSQVYQC 1646
Query: 309 --------SWQISPWTHCSVSCGGGVQRRKIWCEDVLSGRKQDDIECSEIKPREQRDCEM 154
+W++ W+ CSV+CG G+ +R++ C + D+ + +KP Q+ C
Sbjct: 1647 INSCLHLATWKVGKWSKCSVTCGIGIMKRQVKC--ITKHGLSSDLCLNHLKPGAQKKCYA 1704
Query: 153 PPCRS 139
C+S
Sbjct: 1705 NDCKS 1709
Score = 250 bits (638), Expect = 3e-64
Identities = 180/675 (26%), Positives = 284/675 (41%), Gaps = 70/675 (10%)
Frame = -1
Query: 2232 WRVTDTWTECDRAC-RGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRW 2056
W ++ W+EC C +G + +++ C H D C + KP+ + C + W
Sbjct: 1023 WAASE-WSECLVTCGKGTKQRQVWCQLNVDHLS--DGFCNSSTKPESLSP-CELHTCASW 1078
Query: 2055 ITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYID-CSG-- 1885
C+ CG G + + V CV +E C S+PSD SC + CS
Sbjct: 1079 QVGPWGPCTTTCGHGYQMRDVKCVNELASAVLEDTE--CHEASRPSDRQSCVLTPCSFIS 1136
Query: 1884 ---------------RKWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQK 1750
+W +G WT CS +CG G R C D +R DES C +
Sbjct: 1137 KLETALLPTVLIKKMAQWRHGSWTPCSVSCG-RGTQARYVSCRDALDRIADESYCAHLPR 1195
Query: 1749 EATERECNRIPCPRWVYGHWSECSRSCDGGVKMRHAQCLD----------------AADR 1618
A +C PC W G WS CS SC G R C++ ++
Sbjct: 1196 PAEIWDCFT-PCGEWQAGDWSPCSASCGHGKTTRQVLCMNYHQPIDENYCDPEVRPLMEQ 1254
Query: 1617 ETHTSRCGPAQ--------------------TQE-HCNEHACTW-------WQFGVWSDC 1522
E + C PA TQ+ NE+ W+ G W C
Sbjct: 1255 ECSLAACPPAHSHFPSSPVQPSYYLSTNLPLTQKLEDNENQVVHPSVRGNQWRTGPWGQC 1314
Query: 1521 SAKCGDGVQYRDANCTDRH-RSVLPEHRCLKMEKIITKPCHRESCPKYKLGEWSQCSVSC 1345
S+ C G+Q+R C D + +S K ++ + C CP++ G W +CS +C
Sbjct: 1315 SSSCSGGLQHRAVVCQDENGQSASYCDAASKPPEL--QQCGPGPCPQWNYGNWGECSQTC 1372
Query: 1344 EDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPF---WRNTDWSACSVSC 1174
G SR V C NG ++ C + P+ Q C++ CP W W++CS SC
Sbjct: 1373 GGGIKSRLVICQFPNGQILEDHNCEIVNKPPSVIQ-CHMHACPADVSWHQEPWTSCSASC 1431
Query: 1173 GIGHRERTTECIYR-EQSVDASFCGDTKMPETSQTCHLLPCTSWKPSHWSPCSVTCGSGI 997
G G + R CI + ++ ++ + C + P T + C + C SWK + W+ CSVTCGSG+
Sbjct: 1432 GKGRKYREVFCIDQFQRKLEDTNCSQVQKPPTHKACRSVRCPSWKANSWNECSVTCGSGV 1491
Query: 996 QTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGP 817
Q R V C G +V+E CD++TRP ++ C C + +++ + +
Sbjct: 1492 QQRDVYCRLKGVGQVVEE-MCDQSTRPCSQRRCWSQDCVQHKGMERGRLN---------- 1540
Query: 816 WTACSATCGNGTQRRLLKCRDH-VRDLPDEYCNHLDKEVSTRNCRLRDCSYWKM-AEWEE 643
CS +C + ++C D+ +R + + N ++++NCR C+Y + A+ +
Sbjct: 1541 ---CSTSCERKDSHQRMECTDNQIRQVNEIVYNSSTISLTSKNCRNPPCNYIVVTADSSQ 1597
Query: 642 CPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPKGEEHIGSW 463
C CG +Q R C + L + V + + ++ C H+ +W
Sbjct: 1598 CANNCGFSYRQ-RITYCTEIPSTKKHKLHRLRPIVYQECPVVPSSQVYQCINSCLHLATW 1656
Query: 462 IIGDWSKCSASCGGG 418
+G WSKCS +CG G
Sbjct: 1657 KVGKWSKCSVTCGIG 1671
Score = 197 bits (501), Expect = 2e-48
Identities = 158/601 (26%), Positives = 234/601 (38%), Gaps = 123/601 (20%)
Frame = -1
Query: 2286 TAAVPNAVIRPISSALYLWRVTDTWTECDRAC-RGQQSQKLMCLDMSTHRQSHDRNCQNV 2110
TA +P +I+ ++ WR +WT C +C RG Q++ + C D + R + + C ++
Sbjct: 1140 TALLPTVLIKKMAQ----WR-HGSWTPCSVSCGRGTQARYVSCRD-ALDRIADESYCAHL 1193
Query: 2109 LKPKQATRMCNIDCST---RWITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLC 1939
+P + DC T W D S CSA CG G+ ++V C+ P E+ C
Sbjct: 1194 PRPAEIW-----DCFTPCGEWQAGDWSPCSASCGHGKTTRQVLCMNYH----QPIDENYC 1244
Query: 1938 DRNSKP-----SDIASC----------------YIDCS--------------------GR 1882
D +P +A+C Y+ + G
Sbjct: 1245 DPEVRPLMEQECSLAACPPAHSHFPSSPVQPSYYLSTNLPLTQKLEDNENQVVHPSVRGN 1304
Query: 1881 KWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWV 1702
+W G W CS +C S G HR C D++ + S C K ++C PCP+W
Sbjct: 1305 QWRTGPWGQCSSSC-SGGLQHRAVVCQDENGQSA--SYCDAASKPPELQQCGPGPCPQWN 1361
Query: 1701 YGHWSECSRSCDGGVKMRHAQCLDAADRETHTSRCG-----PAQTQEHCNEHAC---TWW 1546
YG+W ECS++C GG+K R C + C P+ Q C+ HAC W
Sbjct: 1362 YGNWGECSQTCGGGIKSRLVICQFPNGQILEDHNCEIVNKPPSVIQ--CHMHACPADVSW 1419
Query: 1545 QFGVWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIIT-KPCHRESCPKYKLGE 1369
W+ CSA CG G +YR+ C D+ + L + C +++K T K C CP +K
Sbjct: 1420 HQEPWTSCSASCGKGRKYREVFCIDQFQRKLEDTNCSQVQKPPTHKACRSVRCPSWKANS 1479
Query: 1368 WSQCSVSCEDGWSSRRV------------------------------SCVSGNGTEVDMS 1279
W++CSV+C G R V CV G E
Sbjct: 1480 WNECSVTCGSGVQQRDVYCRLKGVGQVVEEMCDQSTRPCSQRRCWSQDCVQHKGMERGRL 1539
Query: 1278 LCGTASDRPASHQ---------------------------TCNLGTCPFWRNT-DWSACS 1183
C T+ +R SHQ C C + T D S C+
Sbjct: 1540 NCSTSCERKDSHQRMECTDNQIRQVNEIVYNSSTISLTSKNCRNPPCNYIVVTADSSQCA 1599
Query: 1182 VSCGIGHRERTTEC----------IYREQSVDASFCGDTKMPETSQTCH-LLPCTSWKPS 1036
+CG +R+R T C ++R + + C + Q + L +WK
Sbjct: 1600 NNCGFSYRQRITYCTEIPSTKKHKLHRLRPIVYQECPVVPSSQVYQCINSCLHLATWKVG 1659
Query: 1035 HWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKL 856
WS CSVTCG GI R V C G D C + +P +K C + C +++
Sbjct: 1660 KWSKCSVTCGIGIMKRQVKCIT-KHGLSSD--LCLNHLKPGAQKKCYANDCKSFTTCKEI 1716
Query: 855 Q 853
Q
Sbjct: 1717 Q 1717
>gi|47224403|emb|CAG08653.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 1322
Score = 890 bits (2299), Expect = 0.0
Identities = 480/1344 (35%), Positives = 680/1344 (49%), Gaps = 136/1344 (10%)
Frame = -1
Query: 4113 SWDHYVEVLVVADTKMYEYHGRSLEDYVLTLFSTVASIYRHQSLRASXXXXXXXXXXXKT 3934
S+ YVE++V AD KM +HG +LE Y+LT+ S VA++YR S+
Sbjct: 7 SYPRYVELMVTADAKMARHHGPNLEHYILTIMSVVAAVYRDPSVGNLINIMIVKLIVVHN 66
Query: 3933 ENAGPRITQNAQQTLQDFCRWQQYYNDPDDSSVQHHDVAILLTRKDICRSQGKCDTLGLA 3754
E GP ++ NA TL +FC WQQ N DDS HHD A+L+TR+DICR++ KCDTLGLA
Sbjct: 67 EQEGPTVSFNAATTLHNFCVWQQGQNVQDDSHPSHHDTALLITREDICRAKDKCDTLGLA 126
Query: 3753 ELGTMCDMQKSCAIIEDNGLSAAFTIAHELGHVFSIPHDDERKCSTYMPVNKVCKFQSTK 3574
ELGTMCD +SC+I E+NG+SA+FTI + F++PHDD KC
Sbjct: 127 ELGTMCDQYRSCSISEENGISASFTIVVQPR--FNMPHDDNPKCR--------------- 169
Query: 3573 FDKTQFQNNFHIMAPTLEYNTHPWSWSPCSAGMLERFLENNRGQTQCLFDQPVERRYYED 3394
+ ++ +H+MA TL Y+T+PW+WS CS + FL+ G+ CL D+PV R Y
Sbjct: 170 --EAGVKHQYHVMASTLNYDTNPWTWSKCSRKYITEFLDTGYGE--CLLDEPVGRTYELP 225
Query: 3393 VFVRDEPGKKYDAHQQCKFVFGPASELCPYMPTCRRLWCATFYGSQMGCRTQHMPWADGT 3214
+ PG+ Y+A++QC+ +FGP S++CPY+ C+RLWC + G GCRTQHMP ADGT
Sbjct: 226 TLL---PGQIYNANRQCELMFGPGSQICPYLKQCKRLWCTSAEGDHKGCRTQHMPLADGT 282
Query: 3213 PCDESRSMFCHHGACVRLAPESLTKIDGQWGDWRSWGECSRTCGGGVQKGLRDCDSPKPR 3034
C M C HG CV + L + G+WG W + CSR+CGGG + RDC+ P+PR
Sbjct: 283 DC--GHGMHCKHGMCVNKELD-LQPVHGEWGPWGPYSVCSRSCGGGTRSTSRDCNKPEPR 339
Query: 3033 NGGKYCVGQRERYRSCNTQECPWDTQPYREVQCSEFNNKDIGIQGVASTNTHWVPKYANV 2854
NGG++CVG+R ++RSCNT+ CP + +RE QCS+F+ K I G+ + W+PKY+ +
Sbjct: 340 NGGRFCVGRRMKFRSCNTEPCPRGRKDFREEQCSQFDGKHFNINGLPPS-VRWIPKYSGI 398
Query: 2853 APNERCKLYCRLSGSAAFYLLRDKVVDGTPCDRNGDDICVAGACMPAGCDHQLHSTLRRD 2674
+RCKL+CR++G+ A+Y L+D+V+DGTPC + DICV G C AGCDH L+S R D
Sbjct: 399 LMKDRCKLFCRVAGTTAYYQLKDRVIDGTPCGTDTYDICVQGLCRQAGCDHVLNSKARND 458
Query: 2673 KCGVCGGDDSSCKVVKGTFNEQGTFGYNEVMKIPAGSANIDIRQKGYNNMKEDDNYLSLR 2494
KCGVCGGD+SSCK + GTFN+ +GYN V++IPAG+ NIDI+Q Y+ EDDNYL+L
Sbjct: 459 KCGVCGGDNSSCKTMAGTFND-AQYGYNTVVRIPAGATNIDIKQVSYSGKPEDDNYLALS 517
Query: 2493 AANGEFLLNGHFQVSLARQQIAFQDTVLEYSGSDAIIERINGTGPIRSDIYVHVLSVGS- 2317
+ +LNG+F V++ +++I F+ TV+EYSGSD +ERIN T I ++ + VL VG+
Sbjct: 518 DSQSNSVLNGNFVVAMFKREINFKGTVIEYSGSDTKVERINCTERIEEELILQVLCVGNL 577
Query: 2316 HPPDISYEYMTAAVPNAVIRPISSALYLWRVTDTWTECDRACRGQQSQKLMCLDMSTHRQ 2137
+ PD+ Y + N I ++W + +W EC R C G++ +K++C+ S +
Sbjct: 578 YNPDVRYSF------NIPIEE-DKEQFVWDPSGSWLECSRICHGERRRKVVCVRKSDRLE 630
Query: 2136 SHDRNCQNVLKPKQATRMCNIDCSTRWITEDVSSCSAKCGSGQKRQRVSCVK--MEGDRQ 1963
D+ C+++ + + CN DC RW S CSAKCGSG + V C+K + +
Sbjct: 631 VSDQRCEHLPQVAAVSEPCNTDCEVRWHVAGKSDCSAKCGSGYRSLDVQCMKYSLLKRQS 690
Query: 1962 TPASEHLCDRNSKPSDIASCYIDCSGRKWNYGEW-------------------------- 1861
++C KP C+ DC + W Y W
Sbjct: 691 ERVDSNVCANAIKPRSREPCHGDCLLKSWQYSAWSQVQPTAKTSQTDTVRVSGKPPLTSC 750
Query: 1860 ----TSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWVYGH 1693
T CS+TCG G R+SYC+++ RR+ + C Q+ TE C+ PCP+W +
Sbjct: 751 RPLLTQCSKTCG-RGSRSRESYCMNNLGRRLADRECSEHQRLVTE-SCSEQPCPKWSFSE 808
Query: 1692 WSECSRSCDGGVKMRHAQCLDAADRETHTSRCGPA---QTQEHCNEHACTWWQFGVWSDC 1522
WSEC +C GV+ R C + D + C P+ T C C W GVW +C
Sbjct: 809 WSECLVTCGKGVRHRQVFCTTSTDEKLSERFCDPSAKPPTVGTCELPECASWTVGVWGEC 868
Query: 1521 SAKCGDGVQYRDANC-TDRHRSVLPEHRC-LKMEKIITKPCHRESCP------------- 1387
+ CG G Q R C + + + + C + ++ C +CP
Sbjct: 869 AVTCGHGYQMRAVRCVSGSYGDRVDDRECNAAVRPRDSQDCEMPACPWLLPAPSTPRPEK 928
Query: 1386 ------KYKLGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLG 1225
+++ G W+ CSVSC G +R VSC G + S C T RP TC
Sbjct: 929 AIQLLTQWRYGSWTACSVSCGKGKRARYVSCRDARGGVAEESQC-THLPRPPEMSTC-FS 986
Query: 1224 TCPFWRNTDWSACSVSCGIGHRERTTECIYREQSVDASFCGDTKMPETSQTCHLLPCTS- 1048
C WR +WSACSV+CG+G R +C Q VD SFC + P Q C PC S
Sbjct: 987 PCGKWRAGEWSACSVTCGMGKITRHVDCSNYHQPVDQSFCHPDEKPSMEQECIAAPCPSV 1046
Query: 1047 ----------------------------------WKPSHWSPCSVTCGSGIQTRSVSCTR 970
W+ W CS TC G Q R V C
Sbjct: 1047 YRRQRINDQPYGYPQDPGRHPGHSSWNVPSADNQWRTGPWGACSSTCAGGFQRRVVVC-- 1104
Query: 969 GSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATCG 790
+ +CD +P K+C+ C P+ W G W C+ TCG
Sbjct: 1105 -QDANGRSNSYCDERVKPAESKSCDSGPC--------------PL-WNYGVWGECTQTCG 1148
Query: 789 NGTQRRLLKC-RDHVRDLPDEYCNHLDKEVSTRNCRLRDC---SYWKMAEWE-------- 646
G + RL+ C R + L D C+ LDK C L+ C + W W+
Sbjct: 1149 GGRKTRLVVCQRPSGQKLNDYNCDVLDKPPDVEQCNLQPCPGSASWHRRPWKPQKGGASP 1208
Query: 645 --------------------------------ECPATCGTHVQQSRNVTCVSAEDGGRTI 562
C +CG ++ R + CV +T
Sbjct: 1209 PPHHHPPSTPAHLPRCAVRWRELLSLWSDCVNACSVSCGRGTKR-REIVCVYQ---NQTK 1264
Query: 561 LKDVDCDVQKRPTSARNCRLEPCP 490
+++ C RP +A++CR CP
Sbjct: 1265 IEEELCSHLPRPRTAKDCRARGCP 1288
Score = 234 bits (597), Expect = 2e-59
Identities = 173/655 (26%), Positives = 256/655 (38%), Gaps = 125/655 (19%)
Frame = -1
Query: 2232 WRVTDTWTECDRAC-RGQQSQKLMCLDMSTHRQSHDRN----CQNVLKPKQATRMCNIDC 2068
W V ++C C G +S + C+ S ++ +R C N +KP+ + C+ DC
Sbjct: 657 WHVAGK-SDCSAKCGSGYRSLDVQCMKYSLLKRQSERVDSNVCANAIKPR-SREPCHGDC 714
Query: 2067 STR------WI----------TEDV---------------SSCSAKCGSGQKRQRVSCVK 1981
+ W T+ V + CS CG G + + C+
Sbjct: 715 LLKSWQYSAWSQVQPTAKTSQTDTVRVSGKPPLTSCRPLLTQCSKTCGRGSRSRESYCMN 774
Query: 1980 MEGDRQTPASEHLCDRNSKPSDIASCYIDCSGRKWNYGEWTSCSETCGSNGKMHRKSYCV 1801
G R ++ C + + + C KW++ EW+ C TCG G HR+ +C
Sbjct: 775 NLGRR---LADRECSEHQRLVTESCSEQPCP--KWSFSEWSECLVTCGK-GVRHRQVFCT 828
Query: 1800 DDSNRRVDESLCGREQKEATERECNRIPCPRWVYGHWSECSRSCDGGVKMRHAQCLDAA- 1624
++ ++ E C K T C C W G W EC+ +C G +MR +C+ +
Sbjct: 829 TSTDEKLSERFCDPSAKPPTVGTCELPECASWTVGVWGECAVTCGHGYQMRAVRCVSGSY 888
Query: 1623 -----DRETHTSRCGPAQTQEHCNEHACTW-------------------WQFGVWSDCSA 1516
DRE + + P +Q+ C AC W W++G W+ CS
Sbjct: 889 GDRVDDRECNAA-VRPRDSQD-CEMPACPWLLPAPSTPRPEKAIQLLTQWRYGSWTACSV 946
Query: 1515 KCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIITKPCHRESCPKYKLGEWSQCSVSCEDG 1336
CG G + R +C D V E +C + + C K++ GEWS CSV+C G
Sbjct: 947 SCGKGKRARYVSCRDARGGVAEESQCTHLPRPPEMSTCFSPCGKWRAGEWSACSVTCGMG 1006
Query: 1335 WSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPF------------------- 1213
+R V C S VD S C ++P+ Q C CP
Sbjct: 1007 KITRHVDC-SNYHQPVDQSFCHP-DEKPSMEQECIAAPCPSVYRRQRINDQPYGYPQDPG 1064
Query: 1212 ----------------WRNTDWSACSVSCGIGHRERTTECIYREQSVDASFCGDTKMPET 1081
WR W ACS +C G + R C S+C + P
Sbjct: 1065 RHPGHSSWNVPSADNQWRTGPWGACSSTCAGGFQRRVVVC-QDANGRSNSYCDERVKPAE 1123
Query: 1080 SQTCHLLPCTSWKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKT 901
S++C PC W W C+ TCG G +TR V C R S G +++Y CD +P +
Sbjct: 1124 SKSCDSGPCPLWNYGVWGECTQTCGGGRKTRLVVCQRPS-GQKLNDYNCDVLDKPPDVEQ 1182
Query: 900 CEKDTCDG-------PRVLQKLQADVPP---------------IRW--ATGPWT----AC 805
C C G P QK A PP +RW W+ AC
Sbjct: 1183 CNLQPCPGSASWHRRPWKPQKGGASPPPHHHPPSTPAHLPRCAVRWRELLSLWSDCVNAC 1242
Query: 804 SATCGNGTQRRLLKC-RDHVRDLPDEYCNHLDKEVSTRNCRLRDCSYWKMAEWEE 643
S +CG GT+RR + C + + +E C+HL + + ++CR R C WK W E
Sbjct: 1243 SVSCGRGTKRREIVCVYQNQTKIEEELCSHLPRPRTAKDCRARGCPGWKANRWRE 1297
Score = 186 bits (473), Expect = 4e-45
Identities = 143/570 (25%), Positives = 220/570 (38%), Gaps = 101/570 (17%)
Frame = -1
Query: 1551 WWQFGVWSDCSAKCGDGVQYRDANCTDRH-RSVLPEHRCLKMEKI--ITKPCHRESCPKY 1381
W G W +CS C G + R C + R + + RC + ++ +++PC+ + ++
Sbjct: 599 WDPSGSWLECSRIC-HGERRRKVVCVRKSDRLEVSDQRCEHLPQVAAVSEPCNTDCEVRW 657
Query: 1380 KLGEWSQCSVSCEDGWSSRRVSCVSGN-----GTEVDMSLCGTASDRPASHQTCNLGTCP 1216
+ S CS C G+ S V C+ + VD ++C A +P S + C+ G C
Sbjct: 658 HVAGKSDCSAKCGSGYRSLDVQCMKYSLLKRQSERVDSNVCANAI-KPRSREPCH-GDCL 715
Query: 1215 F--WRNTDWSA------------------------------CSVSCGIGHRERTTECIYR 1132
W+ + WS CS +CG G R R + C+
Sbjct: 716 LKSWQYSAWSQVQPTAKTSQTDTVRVSGKPPLTSCRPLLTQCSKTCGRGSRSRESYCMNN 775
Query: 1131 --EQSVDASFCGDTKMPETSQTCHLLPCTSWKPSHWSPCSVTCGSGIQTRSVSCTRGSEG 958
+ D ++ +++C PC W S WS C VTCG G++ R V CT ++
Sbjct: 776 LGRRLADRECSEHQRL--VTESCSEQPCPKWSFSEWSECLVTCGKGVRHRQVFCTTSTDE 833
Query: 957 TIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATCGNGTQ 778
+ E FCD + +P TCE C W G W C+ TCG+G Q
Sbjct: 834 KL-SERFCDPSAKPPTVGTCELPECAS---------------WTVGVWGECAVTCGHGYQ 877
Query: 777 RRLLKC--RDHVRDLPDEYCNHLDKEVSTRNCRLRDCSY-------------------WK 661
R ++C + + D CN + +++C + C + W+
Sbjct: 878 MRAVRCVSGSYGDRVDDRECNAAVRPRDSQDCEMPACPWLLPAPSTPRPEKAIQLLTQWR 937
Query: 660 MAEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPKGE 481
W C +CG +++R V+C A G + ++ C RP C PC
Sbjct: 938 YGSWTACSVSCGKG-KRARYVSCRDARGG---VAEESQCTHLPRPPEMSTC-FSPC---- 988
Query: 480 EHIGSWIIGDWSKCSASCGGGWXXXXX--XXXXXXCDET-----RKPKMFDKCNEELCP- 325
G W G+WS CS +CG G D++ KP M +C CP
Sbjct: 989 ---GKWRAGEWSACSVTCGMGKITRHVDCSNYHQPVDQSFCHPDEKPSMEQECIAAPCPS 1045
Query: 324 -----------------------------PLTNNSWQISPWTHCSVSCGGGVQRRKIWCE 232
P +N W+ PW CS +C GG QRR + C+
Sbjct: 1046 VYRRQRINDQPYGYPQDPGRHPGHSSWNVPSADNQWRTGPWGACSSTCAGGFQRRVVVCQ 1105
Query: 231 DVLSGRKQDDIECSE-IKPREQRDCEMPPC 145
D +GR C E +KP E + C+ PC
Sbjct: 1106 DA-NGRSNS--YCDERVKPAESKSCDSGPC 1132
Score = 163 bits (413), Expect = 3e-38
Identities = 122/465 (26%), Positives = 185/465 (39%), Gaps = 48/465 (10%)
Frame = -1
Query: 1374 GEWSQCSVSCEDGWSSRRVSCV-SGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNTD 1198
G W +CS C G R+V CV + EV C A + CN W
Sbjct: 603 GSWLECSRICH-GERRRKVVCVRKSDRLEVSDQRCEHLPQVAAVSEPCNTDCEVRWHVAG 661
Query: 1197 WSACSVSCGIGHRERTTECIY------REQSVDASFCGDTKMPETSQTCH---LLPCTSW 1045
S CS CG G+R +C+ + + VD++ C + P + + CH LL SW
Sbjct: 662 KSDCSAKCGSGYRSLDVQCMKYSLLKRQSERVDSNVCANAIKPRSREPCHGDCLLK--SW 719
Query: 1044 KPSHWS-------------------PCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNT 922
+ S WS P +C + S +C RGS E +C N
Sbjct: 720 QYSAWSQVQPTAKTSQTDTVRVSGKPPLTSCRPLLTQCSKTCGRGSRSR---ESYCMNNL 776
Query: 921 RPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATCGNGTQRRLLKCRDHVRD 742
RL +++ + R++ + ++ P +W+ W+ C TCG G + R + C +
Sbjct: 777 GRRL---ADRECSEHQRLVTESCSEQPCPKWSFSEWSECLVTCGKGVRHRQVFCTTSTDE 833
Query: 741 -LPDEYCNHLDKEVSTRNCRLRDCSYWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRT 565
L + +C+ K + C L +C+ W + W EC TCG H Q R V CVS G R
Sbjct: 834 KLSERFCDPSAKPPTVGTCELPECASWTVGVWGECAVTCG-HGYQMRAVRCVSGSYGDR- 891
Query: 564 ILKDVDCDVQKRPTSARNCRLEPCP------------KGEEHIGSWIIGDWSKCSASCGG 421
+ D +C+ RP +++C + CP K + + W G W+ CS SCG
Sbjct: 892 -VDDRECNAAVRPRDSQDCEMPACPWLLPAPSTPRPEKAIQLLTQWRYGSWTACSVSCGK 950
Query: 420 GWXXXXXXXXXXXCDETRKPKMFDKCNEELCPPLTNN------SWQISPWTHCSVSCGGG 259
G + +C PP + W+ W+ CSV+CG G
Sbjct: 951 GKRARYVSCRDARGGVAEE----SQCTHLPRPPEMSTCFSPCGKWRAGEWSACSVTCGMG 1006
Query: 258 VQRRKIWCEDVLSGRKQDDIECSEIKPREQRDCEMPPCRSHYHNK 124
R + C + Q E KP +++C PC S Y +
Sbjct: 1007 KITRHVDCSNYHQPVDQSFCHPDE-KPSMEQECIAAPCPSVYRRQ 1050
Score = 154 bits (389), Expect = 2e-35
Identities = 118/468 (25%), Positives = 180/468 (38%), Gaps = 101/468 (21%)
Frame = -1
Query: 2232 WRVTDTWTECDRAC-RGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCN------- 2077
W V W EC C G Q + + C+ S + DR C ++P+ + + C
Sbjct: 860 WTV-GVWGECAVTCGHGYQMRAVRCVSGSYGDRVDDRECNAAVRPRDS-QDCEMPACPWL 917
Query: 2076 ------------IDCSTRWITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDR 1933
I T+W ++CS CG G++ + VSC G A E C
Sbjct: 918 LPAPSTPRPEKAIQLLTQWRYGSWTACSVSCGKGKRARYVSCRDARGG---VAEESQCTH 974
Query: 1932 NSKPSDIASCYIDCSGRKWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQ 1753
+P ++++C+ C KW GEW++CS TCG GK+ R C + ++ VD+S C ++
Sbjct: 975 LPRPPEMSTCFSPCG--KWRAGEWSACSVTCGM-GKITRHVDC-SNYHQPVDQSFCHPDE 1030
Query: 1752 KEATERECNRIPCP-----------------------------------RWVYGHWSECS 1678
K + E+EC PCP +W G W CS
Sbjct: 1031 KPSMEQECIAAPCPSVYRRQRINDQPYGYPQDPGRHPGHSSWNVPSADNQWRTGPWGACS 1090
Query: 1677 RSCDGGVKMRHAQCLDAADRETH--TSRCGPAQTQEHCNEHACTWWQFGVWSDCSAKCGD 1504
+C GG + R C DA R R PA+++ C+ C W +GVW +C+ CG
Sbjct: 1091 STCAGGFQRRVVVCQDANGRSNSYCDERVKPAESKS-CDSGPCPLWNYGVWGECTQTCGG 1149
Query: 1503 GVQYRDANCTDRHRSVLPEHRCLKMEKII-TKPCHRESCP-------------------- 1387
G + R C L ++ C ++K + C+ + CP
Sbjct: 1150 GRKTRLVVCQRPSGQKLNDYNCDVLDKPPDVEQCNLQPCPGSASWHRRPWKPQKGGASPP 1209
Query: 1386 -------------------KYKLGEWSQC----SVSCEDGWSSRRVSCVSGNGTEVDMSL 1276
+ L WS C SVSC G R + CV N T+++ L
Sbjct: 1210 PHHHPPSTPAHLPRCAVRWRELLSLWSDCVNACSVSCGRGTKRREIVCVYQNQTKIEEEL 1269
Query: 1275 CGTASDRPASHQTCNLGTCPFWRNTDWSACSVSCGIGHRERTTECIYR 1132
C + RP + + C CP W+ W + G C++R
Sbjct: 1270 C-SHLPRPRTAKDCRARGCPGWKANRWREVR-TISSGSASEQLRCLHR 1315
Score = 117 bits (293), Expect = 3e-24
Identities = 90/390 (23%), Positives = 145/390 (37%), Gaps = 82/390 (21%)
Frame = -1
Query: 2232 WRVTDTWTECDRAC-RGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRW 2056
WR +WT C +C +G++++ + C D + + + C ++ +P + + C C +W
Sbjct: 936 WRY-GSWTACSVSCGKGKRARYVSCRD-ARGGVAEESQCTHLPRPPEMST-CFSPCG-KW 991
Query: 2055 ITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCY-------- 1900
+ S+CS CG G+ + V C + P + C + KPS C
Sbjct: 992 RAGEWSACSVTCGMGKITRHVDC----SNYHQPVDQSFCHPDEKPSMEQECIAAPCPSVY 1047
Query: 1899 --------------------------IDCSGRKWNYGEWTSCSETCGSNGKMHRKSYCVD 1798
+ + +W G W +CS TC G R+
Sbjct: 1048 RRQRINDQPYGYPQDPGRHPGHSSWNVPSADNQWRTGPWGACSSTCA--GGFQRRVVVCQ 1105
Query: 1797 DSNRRVDESLCGREQKEATERECNRIPCPRWVYGHWSECSRSCDGGVKMRHAQC------ 1636
D+N R S C K A + C+ PCP W YG W EC+++C GG K R C
Sbjct: 1106 DANGR-SNSYCDERVKPAESKSCDSGPCPLWNYGVWGECTQTCGGGRKTRLVVCQRPSGQ 1164
Query: 1635 ------LDAADRETHTSRCG-----------------------------PAQTQEHCNEH 1561
D D+ +C P T H
Sbjct: 1165 KLNDYNCDVLDKPPDVEQCNLQPCPGSASWHRRPWKPQKGGASPPPHHHPPSTPAHLPRC 1224
Query: 1560 ACTWWQF-GVWSDC----SAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIIT-KPCHR 1399
A W + +WSDC S CG G + R+ C ++++ + E C + + T K C
Sbjct: 1225 AVRWRELLSLWSDCVNACSVSCGRGTKRREIVCVYQNQTKIEEELCSHLPRPRTAKDCRA 1284
Query: 1398 ESCPKYKLGEWSQCSVSCEDGWSSRRVSCV 1309
CP +K W + + G +S ++ C+
Sbjct: 1285 RGCPGWKANRWREVR-TISSGSASEQLRCL 1313
Score = 73.2 bits (178), Expect = 6e-11
Identities = 58/250 (23%), Positives = 92/250 (36%), Gaps = 43/250 (17%)
Frame = -1
Query: 2253 ISSALYLWRVTDTWTECDRACRGQ-QSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCN 2077
+ SA WR T W C C G Q + ++C D + S+ C +KP ++ + C+
Sbjct: 1074 VPSADNQWR-TGPWGACSSTCAGGFQRRVVVCQDANGRSNSY---CDERVKPAES-KSCD 1128
Query: 2076 IDCSTRWITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYI 1897
W C+ CG G+K + V C + G + +++ CD KP D+ C +
Sbjct: 1129 SGPCPLWNYGVWGECTQTCGGGRKTRLVVCQRPSGQK---LNDYNCDVLDKPPDVEQCNL 1185
Query: 1896 D-CSGR-KWNYGEW----------------------------------------TSCSET 1843
C G W+ W +CS +
Sbjct: 1186 QPCPGSASWHRRPWKPQKGGASPPPHHHPPSTPAHLPRCAVRWRELLSLWSDCVNACSVS 1245
Query: 1842 CGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWVYGHWSECSRSCDG 1663
CG G R+ CV + +++E LC + T ++C CP W W E R+
Sbjct: 1246 CG-RGTKRREIVCVYQNQTKIEEELCSHLPRPRTAKDCRARGCPGWKANRWREV-RTISS 1303
Query: 1662 GVKMRHAQCL 1633
G +CL
Sbjct: 1304 GSASEQLRCL 1313
Score = 71.2 bits (173), Expect = 2e-10
Identities = 74/332 (22%), Positives = 122/332 (36%), Gaps = 42/332 (12%)
Frame = -1
Query: 1008 GSGIQTRSVSCTRGSEGTIVDEYFCDRNT-RPRLKKTCEKDTCDGPRVLQKLQADVPPIR 832
GS + ++CT E ++ + C N P ++ + ++ D
Sbjct: 549 GSDTKVERINCTERIEEELILQVLCVGNLYNPDVRYSFNIP----------IEEDKEQFV 598
Query: 831 W-ATGPWTACSATCGNGTQRRLLKC--RDHVRDLPDEYCNHLDKEVSTRNCRLRDCSY-W 664
W +G W CS C +G +RR + C + ++ D+ C HL + + DC W
Sbjct: 599 WDPSGSWLECSRIC-HGERRRKVVCVRKSDRLEVSDQRCEHLPQVAAVSEPCNTDCEVRW 657
Query: 663 KMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPKG 484
+A +C A CG+ +S +V C+ R + VD +V R+ EPC G
Sbjct: 658 HVAGKSDCSAKCGSG-YRSLDVQCMKYSLLKRQ-SERVDSNVCANAIKPRS--REPC-HG 712
Query: 483 EEHIGSWIIGDWS------------------------------KCSASCGGGWXXXXX-- 400
+ + SW WS +CS +CG G
Sbjct: 713 DCLLKSWQYSAWSQVQPTAKTSQTDTVRVSGKPPLTSCRPLLTQCSKTCGRGSRSRESYC 772
Query: 399 -----XXXXXXCDETRKPKMFDKCNEELCPPLTNNSWQISPWTHCSVSCGGGVQRRKIWC 235
+ + + C+E+ CP W S W+ C V+CG GV+ R+++C
Sbjct: 773 MNNLGRRLADRECSEHQRLVTESCSEQPCP-----KWSFSEWSECLVTCGKGVRHRQVFC 827
Query: 234 EDVLSGRKQDDIECSEIKPREQRDCEMPPCRS 139
+ + KP CE+P C S
Sbjct: 828 TTSTDEKLSERFCDPSAKPPTVGTCELPECAS 859
>gi|34867907|ref|XP_235610.2| similar to metalloprotease-disintegrin
protease [Rattus norvegicus]
Length = 1923
Score = 855 bits (2210), Expect = 0.0
Identities = 537/1588 (33%), Positives = 750/1588 (46%), Gaps = 144/1588 (9%)
Frame = -1
Query: 4464 GGMSRTDPD---CIYRAHVKGVHQH-SIVNLCDSEDGLYGMLALPSGIHTVEPIISGNGT 4297
GG S PD C YR V H ++ +LC GL G G + +EP++ +G+
Sbjct: 163 GGRSAEPPDLRHCFYRGQVNAREDHIAVFSLCG---GLMGTFKANDGEYFLEPVLKADGS 219
Query: 4296 EHDGASRHRQHLVRKFDPMHFKSFDHLNS-----TSVNETETTVA---TWQDQWEDVIER 4141
EH+ ++ HL+ + + +F S S N+TE T ++++ D+ R
Sbjct: 220 EHED-DHNKPHLIYRQEVKR-NAFVRSQSHGPCGVSENQTEKTALPSPSFRNTTGDLNRR 277
Query: 4140 K--------------ARSRRAANSWDHYVEVLVVADTKMYEYHGRSLEDYVLTLFSTVAS 4003
K +RS+R S+ YVEV+V AD KM +HG++L+ YVLTL S VA+
Sbjct: 278 KGAVFGLEGERSRLHSRSKRFL-SYPRYVEVMVTADAKMVRHHGQNLQHYVLTLMSIVAA 336
Query: 4002 IYRHQSLRASXXXXXXXXXXXKTENAGPRITQNAQQTLQDFCRWQQYYNDPDDSSVQHHD 3823
IY+ S+ +E GP I+ NA TL++FC WQQ N DD+ HHD
Sbjct: 337 IYKDSSIGNLINIVIVKLVIIHSEQEGPVISFNAATTLRNFCLWQQSQNVLDDAHPSHHD 396
Query: 3822 VAILLTRKDICRSQGKCDTLGLAELGTMCDMQKSCAIIEDNGLSAAFTIAHELGHVFSIP 3643
A+L+TR+DIC ++ KCDTLGLAELGT+CD +SC+I E+NGLSAAFTIAHELGHVF++P
Sbjct: 397 TAVLITREDICGAKEKCDTLGLAELGTLCDPSRSCSISEENGLSAAFTIAHELGHVFNVP 456
Query: 3642 HDDERKCSTYMPVNKVCKFQSTKFDKTQFQNNFHIMAPTLEYNTHPWSWSPCSAGMLERF 3463
HDD KC K TK + +H+MAPTL Y+T PW+WS CS + F
Sbjct: 457 HDDSFKC----------KESGTK-------HQYHVMAPTLNYHTSPWTWSACSQKHITEF 499
Query: 3462 LENNRGQTQCLFDQPVERRYYEDVFVRDEPGKKYDAHQQCKFVFGPASELCPYMPTCRRL 3283
L+ G+ CL D+P R Y + PG YD ++QC+ +FGP S++CPY+ CRRL
Sbjct: 500 LDTGHGE--CLLDKPNGRTYDLSPQL---PGSVYDGNKQCELMFGPGSQVCPYLKQCRRL 554
Query: 3282 WCATFYGSQMGCRTQHMPWADGTPCDESRSMFCHHGACVRLAPESLTKIDGQWGDWRSWG 3103
WC + G GCRTQHMP ADGT
Sbjct: 555 WCTSAEGVHKGCRTQHMPLADGT------------------------------------- 577
Query: 3102 ECSRTCGGGVQKGLRDCDSPKPRNGGKYCVGQRERYRSCNTQECPWDTQPYREVQCSEFN 2923
+CG G+ L PRNGG+YCVG+R ++RSCNT CP + +RE QCS+F+
Sbjct: 578 ----SCGPGMVGFLTG-----PRNGGRYCVGRRMKFRSCNTDSCPKGKRDFREKQCSDFD 628
Query: 2922 NKDIGIQGVASTNTHWVPKYANVAPNERCKLYCRLSGSAAFYLLRDKVVDGTPCDRNGDD 2743
K I G+ N W+PKY+ +A +RCKLYCR++G+ +FY L+D+V DGTPC +D
Sbjct: 629 GKHFDISGLPP-NVRWLPKYSGIAVKDRCKLYCRVAGTTSFYQLKDRVADGTPCGTETND 687
Query: 2742 ICVAGACMPAGCDHQLHSTLRRDKCGVCGGDDSSCKVVKGTFNEQGTFGYNEVMKIPAGS 2563
ICV G C AGCDH L+S +RDKCGVCGGD+SSC+ + G FN +GYN V+KIPAG+
Sbjct: 688 ICVQGLCRQAGCDHVLNSKAKRDKCGVCGGDNSSCQTLAGVFN-SAHYGYNVVVKIPAGA 746
Query: 2562 ANIDIRQKGYNNMKEDDNYLSLRAANGEFLLNGHFQVSLARQQIAFQDTVLEYSGSDAII 2383
NI+I Q Y+ EDDNYL+L G FLLNG+F VS+A+++I Q V EYSGS+ I
Sbjct: 747 TNIEILQHSYSGRPEDDNYLALSDTQGNFLLNGNFVVSMAKKEINIQGAVFEYSGSNNSI 806
Query: 2382 ERINGTGPIRSDIYVHVLSVGS-HPPDISYEYMTAAVPNAVIRPISSALYLWRVTDTWTE 2206
ERIN T + +++ + VL VG+ + PD+ Y + N I S+ L+ W W +
Sbjct: 807 ERINSTDRLEAELVLQVLCVGNLYNPDVHYIF------NIPIEERSN-LFSWDPYGPWQD 859
Query: 2205 CDRACRGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRWITEDVSSCSA 2026
C + C+G +K+ C+ S D++C ++ P T CN DC RW S CS+
Sbjct: 860 CTKMCQGLHRRKIACIRKSDRAVVSDQSCSHLPLPLFVTERCNTDCELRWHITGKSDCSS 919
Query: 2025 KCGSGQKRQRVSCVK--MEGDRQTPASEHLCDRNSKPSDIASCYIDCSGRKWNYGEWTSC 1852
+CG G + V C+K + + P + C KP + C+ C +W+Y EW+ C
Sbjct: 920 QCGQGYRTLDVHCMKYSVHKGQTVPVGDQYCGDQLKPPNREPCHGSCVLTRWHYSEWSQC 979
Query: 1851 SETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWVYGHWSECSRS 1672
S +CG G+ R+SYCV+ R+ E C +E CN PCP W WSEC +
Sbjct: 980 SRSCG-GGEKTRESYCVNGFGHRLAEREC-QELPRVVLGNCNDFPCPGWATSEWSECPVT 1037
Query: 1671 CDGGVKMRHAQCL--------DAADRETHTSRCGPAQTQEHCNEHACTWWQFGVWSDCSA 1516
C G+K R C D D T GP C AC W G W C+
Sbjct: 1038 CGKGMKQRQVWCQRSEDPVGDDFCDASTKPESLGP------CELRACASWHVGPWGSCTV 1091
Query: 1515 KCGDGVQYRDANC-TDRHRSVLPEHRCLKMEKIITKPCHRES------------------ 1393
CG G Q R C ++ +VL + C + ++P R+
Sbjct: 1092 TCGHGYQVRAVKCVSEILGTVLDDRECPR----ASRPSDRQGCFEGLYAFSADELNCAHW 1147
Query: 1392 ------------CPKYKLGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPA 1249
C +++ G+WS CS SC G ++RRV CV+ + VD S C RP
Sbjct: 1148 ARPAEVSLCFSPCGEWQAGDWSPCSASCGHGKTTRRVLCVNYHQL-VDESYC-DPEGRPV 1205
Query: 1248 SHQTCNLGTCP------------------------------------------FWRNTDW 1195
+ Q C L CP WR W
Sbjct: 1206 TEQECRLAACPPSYSRSPSSSEQPSHGPGRNVPLTHKPEENPDQGVQLSIRGNQWRTGPW 1265
Query: 1194 SACSVSCGIGHRERTTECIYREQSVDASFCGDTKMPETSQTCHLLPC---TSWKPSHWSP 1024
AC+ +CG G + R C + + + + P + CHL C SW W
Sbjct: 1266 GACTQTCGAGVKSRFVICQFPDGQMAQEHSCELPKPPSMMQCHLRACPDDVSWYRGSWKS 1325
Query: 1023 -------------CSVTCGSGIQTRSVSCTRGSEGTIVDEY-------FCDRNTRPRLKK 904
C S + S+ E + ++ D L
Sbjct: 1326 QLTNFTLERMAPLLGAVCLSNRLSMSLIKMLTVESDCLPKFTECLSVTLGDIRGSSELPG 1385
Query: 903 TCEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATCGNGTQRRLLKCRDHV-RDLPDEY 727
T E C G R + + ++ CSA+CG G + R + C D V R L ++Y
Sbjct: 1386 TPEASGCVGARSVDTTAQTLLVLK------AKCSASCGKGIKYREVLCIDQVQRKLEEKY 1439
Query: 726 CNHLDKEVSTRNCRLRDCSYWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKDVD 547
C+HL K + + CR C WK +W+EC TCG+ VQQ R V C G + +D+
Sbjct: 1440 CSHLHKPRTHKPCRSGRCPSWKANKWKECSVTCGSGVQQ-REVYCRLRGTG--RVAEDM- 1495
Query: 546 CDVQKRPTSARNCRLEPCPKGEEHIGSWIIGDWSKCSASCGGGWX--------XXXXXXX 391
C+ RP R C + C + + W GDW CS SC
Sbjct: 1496 CEPSTRPQVQRPCWHQDCTRYQ-----WTTGDWLDCSTSCKKKETYRLVKCVNERNMQVN 1550
Query: 390 XXXCDETRKPKMFDKCNEELCP--PLTNNSWQISPWTHCSVSCGGGVQRRKIWCEDVLSG 217
CD KP KC C +T +S Q C+ +CG +R +C +
Sbjct: 1551 ESLCDPLTKPVSIKKCRNSHCKYMVVTGDSSQ------CAGNCGLTYSQRITYCTRIQPP 1604
Query: 216 RKQDDIECSEIKPREQRDCEMPPCRSHY 133
+K + +++P C + P Y
Sbjct: 1605 KK--NAFHHQLRPVNYGQCPVIPSPQVY 1630
Score = 228 bits (580), Expect = 1e-57
Identities = 183/724 (25%), Positives = 275/724 (37%), Gaps = 113/724 (15%)
Frame = -1
Query: 2250 SSALYLWRVTDTWTECDRACRG-QQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNI 2074
S L W ++ W++C R+C G +++++ C++ HR + +R CQ + P+ CN
Sbjct: 965 SCVLTRWHYSE-WSQCSRSCGGGEKTRESYCVNGFGHRLA-ERECQEL--PRVVLGNCND 1020
Query: 2073 DCSTRWITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYID 1894
W T + S C CG G K+++V C + E P + CD ++KP + C +
Sbjct: 1021 FPCPGWATSEWSECPVTCGKGMKQRQVWCQRSED----PVGDDFCDASTKPESLGPCELR 1076
Query: 1893 CSGRKWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRV-DESLCGREQKEATERECNR-- 1723
W+ G W SC+ TCG +G R CV + V D+ C R + + + C
Sbjct: 1077 ACA-SWHVGPWGSCTVTCG-HGYQVRAVKCVSEILGTVLDDRECPRASRPSDRQGCFEGL 1134
Query: 1722 -----------------------IPCPRWVYGHWSECSRSCDGGVKMRHAQCLDAADR-- 1618
PC W G WS CS SC G R C++
Sbjct: 1135 YAFSADELNCAHWARPAEVSLCFSPCGEWQAGDWSPCSASCGHGKTTRRVLCVNYHQLVD 1194
Query: 1617 ETHTSRCGPAQTQEHCNEHAC--------------------------------------- 1555
E++ G T++ C AC
Sbjct: 1195 ESYCDPEGRPVTEQECRLAACPPSYSRSPSSSEQPSHGPGRNVPLTHKPEENPDQGVQLS 1254
Query: 1554 ---TWWQFGVWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIITKPCHRESCP- 1387
W+ G W C+ CG GV+ R C + EH C + CH +CP
Sbjct: 1255 IRGNQWRTGPWGACTQTCGAGVKSRFVICQFPDGQMAQEHSCELPKPPSMMQCHLRACPD 1314
Query: 1386 --KYKLGEWSQ--CSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTC---NL 1228
+ G W + + E C+S + + + SD C L
Sbjct: 1315 DVSWYRGSWKSQLTNFTLERMAPLLGAVCLSNRLSMSLIKMLTVESDCLPKFTECLSVTL 1374
Query: 1227 GT---------------CPFWRNTDWSA---------CSVSCGIGHRERTTECIYREQ-S 1123
G C R+ D +A CS SCG G + R CI + Q
Sbjct: 1375 GDIRGSSELPGTPEASGCVGARSVDTTAQTLLVLKAKCSASCGKGIKYREVLCIDQVQRK 1434
Query: 1122 VDASFCGDTKMPETSQTCHLLPCTSWKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDE 943
++ +C P T + C C SWK + W CSVTCGSG+Q R V C G + ++
Sbjct: 1435 LEEKYCSHLHKPRTHKPCRSGRCPSWKANKWKECSVTCGSGVQQREVYCRLRGTGRVAED 1494
Query: 942 YFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATCGNGTQRRLLK 763
C+ +TRP++++ C C +W TG W CS +C RL+K
Sbjct: 1495 -MCEPSTRPQVQRPCWHQDC-------------TRYQWTTGDWLDCSTSCKKKETYRLVK 1540
Query: 762 C-RDHVRDLPDEYCNHLDKEVSTRNCRLRDCSYWKM-AEWEECPATCGTHVQQSRNVTCV 589
C + + + C+ L K VS + CR C Y + + +C CG Q R C
Sbjct: 1541 CVNERNMQVNESLCDPLTKPVSIKKCRNSHCKYMVVTGDSSQCAGNCGLTYSQ-RITYCT 1599
Query: 588 SAEDGGRTI----LKDVD---CDVQKRPTSARNCRLEPCPKGEEHIGSWIIGDWSKCSAS 430
+ + L+ V+ C V P C + C +G +W +G WSKCS +
Sbjct: 1600 RIQPPKKNAFHHQLRPVNYGQCPVIPSP-QVYKCDIRSCLRG----ATWKVGKWSKCSVT 1654
Query: 429 CGGG 418
CG G
Sbjct: 1655 CGNG 1658
Score = 143 bits (360), Expect = 5e-32
Identities = 87/290 (30%), Positives = 133/290 (45%), Gaps = 21/290 (7%)
Frame = -1
Query: 1689 SECSRSCDGGVKMRHAQCLDAADRETHTSRCG---PAQTQEHCNEHACTWWQFGVWSDCS 1519
++CS SC G+K R C+D R+ C +T + C C W+ W +CS
Sbjct: 1410 AKCSASCGKGIKYREVLCIDQVQRKLEEKYCSHLHKPRTHKPCRSGRCPSWKANKWKECS 1469
Query: 1518 AKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKI-ITKPCHRESCPKYK--LGEWSQCSVS 1348
CG GVQ R+ C R + E C + + +PC + C +Y+ G+W CS S
Sbjct: 1470 VTCGSGVQQREVYCRLRGTGRVAEDMCEPSTRPQVQRPCWHQDCTRYQWTTGDWLDCSTS 1529
Query: 1347 CEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNT-DWSACSVSCG 1171
C+ + R V CV+ +V+ SLC + +P S + C C + T D S C+ +CG
Sbjct: 1530 CKKKETYRLVKCVNERNMQVNESLCDPLT-KPVSIKKCRNSHCKYMVVTGDSSQCAGNCG 1588
Query: 1170 IGHRERTTECI-----------YREQSVDASFCGDTKMPETSQTCHLLPC---TSWKPSH 1033
+ + +R T C ++ + V+ C P+ + C + C +WK
Sbjct: 1589 LTYSQRITYCTRIQPPKKNAFHHQLRPVNYGQCPVIPSPQVYK-CDIRSCLRGATWKVGK 1647
Query: 1032 WSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTC 883
WS CSVTCG+GI R V+C R G D C + +P +K C + C
Sbjct: 1648 WSKCSVTCGNGIMERRVAC-RTENGWPSD--LCLKRLKPDAQKKCYANDC 1694
Score = 120 bits (302), Expect = 3e-25
Identities = 134/612 (21%), Positives = 195/612 (30%), Gaps = 100/612 (16%)
Frame = -1
Query: 2208 ECDRACRGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRWITEDVSSCS 2029
EC RA R Q C + + + NC + +P + + +C C W D S CS
Sbjct: 1117 ECPRASRPSDRQG--CFEGLYAFSADELNCAHWARPAEVS-LCFSPCG-EWQAGDWSPCS 1172
Query: 2028 AKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASC------------------ 1903
A CG G+ +RV CV E CD +P C
Sbjct: 1173 ASCGHGKTTRRVLCVNYH----QLVDESYCDPEGRPVTEQECRLAACPPSYSRSPSSSEQ 1228
Query: 1902 -----------------------YIDCSGRKWNYGEWTSCSETCGSNGKMHRKSYCVDDS 1792
+ G +W G W +C++TCG+ G R C
Sbjct: 1229 PSHGPGRNVPLTHKPEENPDQGVQLSIRGNQWRTGPWGACTQTCGA-GVKSRFVICQFPD 1287
Query: 1791 NRRVDESLCGREQKEATERECNRIPCPRWVYGHWSECSRSCDGGVKMRHAQCLDAADRET 1612
+ E C K + +C+ CP V + R A L A
Sbjct: 1288 GQMAQEHSC-ELPKPPSMMQCHLRACPDDVSWYRGSWKSQLTNFTLERMAPLLGAVCLSN 1346
Query: 1611 HTSRCGPAQTQEHCNEHACTWWQFGVWSDCSAKCGD--GVQYRDANCTDRHRSVLPEHRC 1438
S V SDC K + V D + C
Sbjct: 1347 RLSMS--------------LIKMLTVESDCLPKFTECLSVTLGDIRGSSELPGTPEASGC 1392
Query: 1437 LKMEKIITKPCHRESCPKYKLGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASD 1258
+ + ++ + L ++CS SC G R V C+ +++ C
Sbjct: 1393 VGARSV-------DTTAQTLLVLKAKCSASCGKGIKYREVLCIDQVQRKLEEKYCSHLH- 1444
Query: 1257 RPASHQTCNLGTCPFWRNTDWSACSVSCGIGHRERTTECIYREQS-VDASFCGDTKMPET 1081
+P +H+ C G CP W+ W CSV+CG G ++R C R V C + P+
Sbjct: 1445 KPRTHKPCRSGRCPSWKANKWKECSVTCGSGVQQREVYCRLRGTGRVAEDMCEPSTRPQV 1504
Query: 1080 SQTCHLLPCT--SWKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRP-RL 910
+ C CT W W CS +C R V C V+E CD T+P +
Sbjct: 1505 QRPCWHQDCTRYQWTTGDWLDCSTSCKKKETYRLVKCVN-ERNMQVNESLCDPLTKPVSI 1563
Query: 909 KK-----------TCEKDTCDG-------------------------------------- 877
KK T + C G
Sbjct: 1564 KKCRNSHCKYMVVTGDSSQCAGNCGLTYSQRITYCTRIQPPKKNAFHHQLRPVNYGQCPV 1623
Query: 876 ---PRVLQ-KLQADVPPIRWATGPWTACSATCGNGTQRRLLKCRDHVRDLPDEYCNHLDK 709
P+V + +++ + W G W+ CS TCGNG R + CR P + C K
Sbjct: 1624 IPSPQVYKCDIRSCLRGATWKVGKWSKCSVTCGNGIMERRVACRTE-NGWPSDLCLKRLK 1682
Query: 708 EVSTRNCRLRDC 673
+ + C DC
Sbjct: 1683 PDAQKKCYANDC 1694
Score = 117 bits (294), Expect = 2e-24
Identities = 81/288 (28%), Positives = 115/288 (39%), Gaps = 21/288 (7%)
Frame = -1
Query: 1854 CSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWVYGHWSECSR 1675
CS +CG G +R+ C+D R+++E C K T + C CP W W ECS
Sbjct: 1412 CSASCGK-GIKYREVLCIDQVQRKLEEKYCSHLHKPRTHKPCRSGRCPSWKANKWKECSV 1470
Query: 1674 SCDGGVKMRHAQCLDAADRETHTSRCGPA---QTQEHCNEHACT--WWQFGVWSDCSAKC 1510
+C GV+ R C C P+ Q Q C CT W G W DCS C
Sbjct: 1471 TCGSGVQQREVYCRLRGTGRVAEDMCEPSTRPQVQRPCWHQDCTRYQWTTGDWLDCSTSC 1530
Query: 1509 GDGVQYRDANCTDRHRSVLPEHRCLKMEKIIT-KPCHRESCPKYKL--GEWSQCSVSCED 1339
YR C + + E C + K ++ K C C KY + G+ SQC+ +C
Sbjct: 1531 KKKETYRLVKCVNERNMQVNESLCDPLTKPVSIKKCRNSHC-KYMVVTGDSSQCAGNCGL 1589
Query: 1338 GWSSRRVSCVSGNGTE----------VDMSLCGTASDRPASHQTCNLGTC---PFWRNTD 1198
+S R C + V+ C P ++ C++ +C W+
Sbjct: 1590 TYSQRITYCTRIQPPKKNAFHHQLRPVNYGQCPVIPS-PQVYK-CDIRSCLRGATWKVGK 1647
Query: 1197 WSACSVSCGIGHRERTTECIYREQSVDASFCGDTKMPETSQTCHLLPC 1054
WS CSV+CG G ER C E + C P+ + C+ C
Sbjct: 1648 WSKCSVTCGNGIMERRVAC-RTENGWPSDLCLKRLKPDAQKKCYANDC 1694
Score = 117 bits (293), Expect = 3e-24
Identities = 87/308 (28%), Positives = 128/308 (41%), Gaps = 21/308 (6%)
Frame = -1
Query: 2079 NIDCSTRWITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCY 1900
++D + + + + CSA CG G K + V C+ Q E C KP C
Sbjct: 1397 SVDTTAQTLLVLKAKCSASCGKGIKYREVLCIDQV---QRKLEEKYCSHLHKPRTHKPCR 1453
Query: 1899 IDCSGR--KWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECN 1726
SGR W +W CS TCGS G R+ YC RV E +C + +R C
Sbjct: 1454 ---SGRCPSWKANKWKECSVTCGS-GVQQREVYCRLRGTGRVAEDMCEPSTRPQVQRPCW 1509
Query: 1725 RIPCPR--WVYGHWSECSRSCDGGVKMRHAQCLDAADRETHTSRCGPAQ---TQEHCNEH 1561
C R W G W +CS SC R +C++ + + + S C P + + C
Sbjct: 1510 HQDCTRYQWTTGDWLDCSTSCKKKETYRLVKCVNERNMQVNESLCDPLTKPVSIKKCRNS 1569
Query: 1560 ACTWWQF-GVWSDCSAKCGDGVQYRDANCT--------DRHRSVLPEH--RCLKMEKIIT 1414
C + G S C+ CG R CT H + P + +C +
Sbjct: 1570 HCKYMVVTGDSSQCAGNCGLTYSQRITYCTRIQPPKKNAFHHQLRPVNYGQCPVIPSPQV 1629
Query: 1413 KPCHRESCPK---YKLGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASH 1243
C SC + +K+G+WS+CSV+C +G RRV+C + NG D+ L +P +
Sbjct: 1630 YKCDIRSCLRGATWKVGKWSKCSVTCGNGIMERRVACRTENGWPSDLCL---KRLKPDAQ 1686
Query: 1242 QTCNLGTC 1219
+ C C
Sbjct: 1687 KKCYANDC 1694
Score = 109 bits (273), Expect = 6e-22
Identities = 75/292 (25%), Positives = 132/292 (44%), Gaps = 19/292 (6%)
Frame = -1
Query: 2208 ECDRAC-RGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRWITEDVSSC 2032
+C +C +G + ++++C+D R+ ++ C ++ KP+ + C W C
Sbjct: 1411 KCSASCGKGIKYREVLCIDQ-VQRKLEEKYCSHLHKPR-THKPCRSGRCPSWKANKWKEC 1468
Query: 2031 SAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYI-DCSGRKWNYGEWTS 1855
S CGSG +++ V C ++ G + +E +C+ +++P C+ DC+ +W G+W
Sbjct: 1469 SVTCGSGVQQREVYC-RLRGTGRV--AEDMCEPSTRPQVQRPCWHQDCTRYQWTTGDWLD 1525
Query: 1854 CSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWVY-GHWSECS 1678
CS +C + +R CV++ N +V+ESLC K + ++C C V G S+C+
Sbjct: 1526 CSTSC-KKKETYRLVKCVNERNMQVNESLCDPLTKPVSIKKCRNSHCKYMVVTGDSSQCA 1584
Query: 1677 RSCDGGVKMRHAQCLDAAD----------RETHTSRCG--PAQTQEHCNEHAC---TWWQ 1543
+C R C R + +C P+ C+ +C W+
Sbjct: 1585 GNCGLTYSQRITYCTRIQPPKKNAFHHQLRPVNYGQCPVIPSPQVYKCDIRSCLRGATWK 1644
Query: 1542 FGVWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLK-MEKIITKPCHRESC 1390
G WS CS CG+G+ R C R + P CLK ++ K C+ C
Sbjct: 1645 VGKWSKCSVTCGNGIMERRVAC--RTENGWPSDLCLKRLKPDAQKKCYANDC 1694
Score = 72.4 bits (176), Expect = 1e-10
Identities = 47/186 (25%), Positives = 79/186 (42%), Gaps = 11/186 (5%)
Frame = -1
Query: 2238 YLWRVTDTWTECDRACRGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTR 2059
Y W D W +C +C+ +++ +L+ + Q ++ C + KP + N C
Sbjct: 1516 YQWTTGD-WLDCSTSCKKKETYRLVKCVNERNMQVNESLCDPLTKPVSIKKCRNSHCKYM 1574
Query: 2058 WITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQT-------PASEHLCDRNSKPS----DI 1912
+T D S C+ CG ++ C +++ ++ P + C P DI
Sbjct: 1575 VVTGDSSQCAGNCGLTYSQRITYCTRIQPPKKNAFHHQLRPVNYGQCPVIPSPQVYKCDI 1634
Query: 1911 ASCYIDCSGRKWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERE 1732
SC G W G+W+ CS TCG NG M R+ C ++ D LC + K +++
Sbjct: 1635 RSC---LRGATWKVGKWSKCSVTCG-NGIMERRVACRTENGWPSD--LCLKRLKPDAQKK 1688
Query: 1731 CNRIPC 1714
C C
Sbjct: 1689 CYANDC 1694
Score = 39.7 bits (91), Expect = 0.74
Identities = 21/54 (38%), Positives = 30/54 (54%), Gaps = 1/54 (1%)
Frame = -1
Query: 282 CSVSCGGGVQRRKIWCEDVLSGRKQDDIECSEI-KPREQRDCEMPPCRSHYHNK 124
CS SCG G++ R++ C D + RK ++ CS + KPR + C C S NK
Sbjct: 1412 CSASCGKGIKYREVLCIDQVQ-RKLEEKYCSHLHKPRTHKPCRSGRCPSWKANK 1464
>gi|41281882|ref|NP_787047.1| a disintegrin-like and metalloprotease
(reprolysin type) with thrombospondin type 1 motif, 20
isoform 2; a disintegrin-like and metalloprotease with
thrombospondin type 1 motifs 20 [Homo sapiens]
gi|28316227|emb|CAD56160.2| ADAMTS-20 protein [Homo sapiens]
Length = 1502
Score = 845 bits (2182), Expect = 0.0
Identities = 470/1362 (34%), Positives = 670/1362 (48%), Gaps = 99/1362 (7%)
Frame = -1
Query: 4437 CIYRAHVKGVHQH-SIVNLCDSEDGLYGMLALPSGIHTVEPIISGNGTEHDGASRHRQHL 4261
C YR V + ++V+LC GL G +G + +EPI+ +G E++ ++ HL
Sbjct: 129 CFYRGQVNSQEDYKAVVSLCG---GLVGTFKGQNGEYFLEPIMKADGNEYEDG-HNKPHL 184
Query: 4260 VRKFDP----MHFKSFDHLNSTSVNETETTVATWQDQWEDVI------------------ 4147
+ + D + + ++ + + ET T+ + ED+
Sbjct: 185 IYRQDLNNSFLQTLKYCSVSESQIKETSLPFHTYSNMNEDLNVMKERVLGHTSKNVPLKD 244
Query: 4146 ERKARSRRAANSWDHYVEVLVVADTKMYEYHGRSLEDYVLTLFSTVASIYRHQSLRASXX 3967
ER+ ++ S+ Y+E++V AD K+ HG +L++Y+LTL S VA+IY+ S+
Sbjct: 245 ERRHSRKKRLISYPRYIEIMVTADAKVVSAHGSNLQNYILTLMSIVATIYKDPSIGNLIH 304
Query: 3966 XXXXXXXXXKTENAGPRITQNAQQTLQDFCRWQQYYNDPDDSSVQHHDVAILLTRKDICR 3787
E GP I + TL++FC WQQ ND DD HHD A+L+TR DIC
Sbjct: 305 IVVVKLVMIHREEEGPVINFDGATTLKNFCSWQQTQNDLDDVHPSHHDTAVLITRYDICS 364
Query: 3786 SQGKCDTLGLAELGTMCDMQKSCAIIEDNGLSAAFTIAHELGHVFSIPHDDERKCSTYMP 3607
S+ KC+ LGL+ LGT+CD +SC I E+ GL +AFTIAHELGH + HDD +C M
Sbjct: 365 SKEKCNMLGLSYLGTICDPLQSCFINEEKGLISAFTIAHELGHTLGVQHDDNPRCKE-MK 423
Query: 3606 VNKVCKFQSTKFDKTQFQNNFHIMAPTLEYNTHPWSWSPCSAGMLERFLENNRGQTQCLF 3427
V K +H+MAP L ++ PWSWS CS + FLE G +CL
Sbjct: 424 VTK-----------------YHVMAPALSFHMSPWSWSNCSRKYVTEFLETGYG--ECLL 464
Query: 3426 DQPVERRYYEDVFVRDEPGKKYDAHQQCKFVFGPASELCPYMPTCRRLWCATFYGSQMGC 3247
D+P E Y + PG +YD ++QC+ FGP S++CP++ C LWC + GC
Sbjct: 465 DKPDEEIYN---LPSELPGSRYDGNKQCELAFGPGSQMCPHINICMHLWCTSTEKLHKGC 521
Query: 3246 RTQHMPWADGTPCDESRSMFCHHGACVRLAPESLTKIDGQWGDWRSWGECSRTCGGGVQK 3067
TQH+P ADGT C M C HG CV E+ ++G+WG W + CSRTCGGG++
Sbjct: 522 FTQHVPPADGTDC--GPGMHCRHGLCVNKETET-RPVNGEWGPWEPYSSCSRTCGGGIES 578
Query: 3066 GLRDCDSPKPRNGGKYCVGQRERYRSCNTQECPWDTQPYREVQCSEFNNKDIGIQGVAST 2887
R C+ P+PRNGG YCVG+R ++RSCNT CP TQ +RE QCS+FN K + I G+ S
Sbjct: 579 ATRRCNRPEPRNGGNYCVGRRMKFRSCNTDSCPKGTQDFREKQCSDFNGKHLDISGIPS- 637
Query: 2886 NTHWVPKYANVAPNERCKLYCRLSGSAAFYLLRDKVVDGTPCDRNGDDICVAGACMPAGC 2707
N W+P+Y+ V +RCKLYC+++G+ FYLL+D V DGTPC +I AGC
Sbjct: 638 NVRWLPRYSGVGTKDRCKLYCQVAGTNYFYLLKDMVEDGTPCGTESYNIDCNCVLKAAGC 697
Query: 2706 DHQLHSTLRRDKCGVCGGDDSSCKVVKGTFNEQGTFGYNEVMKIPAGSANIDIRQKGYNN 2527
DH L+S+ + DKCGVCGGD+SSCK + G FN +GYN V+KIPAG+ N+DIRQ Y+
Sbjct: 698 DHVLNSSAKIDKCGVCGGDNSSCKTITGVFN-SSHYGYNVVVKIPAGATNVDIRQYSYSG 756
Query: 2526 MKEDDNYLSLRAANGEFLLNGHFQVSLARQQIAFQDTVLEYSGSDAIIERINGTGPIRSD 2347
+ DD+YL+L A G FL NG+F +S ++++I Q TV+EYSGS+ +ERIN T +
Sbjct: 757 -QPDDSYLALSDAEGNFLFNGNFLLSTSKKEINVQGTVIEYSGSNNAVERINSTNRQEKE 815
Query: 2346 IYVHVLSVGS-HPPDISYEYMTAAVPNAVIRPISSALYLWRVTDTWTECDRACRGQQSQK 2170
I + VL VG+ + PD+ Y + N + S ++ W W C + C+G Q +
Sbjct: 816 ILIEVLCVGNLYNPDVHYSF------NIPLEE-RSDMFTWDPYGPWEGCTKMCQGLQRRN 868
Query: 2169 LMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRWITEDVSSCSAKCGSGQKRQRVS 1990
+ C+ S H D+ C ++ P T+ CN DC RW S CS++CG G + +
Sbjct: 869 ITCIHKSDHSVVSDKECDHLPLPSFVTQSCNTDCELRWHVIGKSECSSQCGQGYRTLDIH 928
Query: 1989 CVK--MEGDRQTPASEHLCDRNSKPSDIASCYIDCSGRKWNYGEWTSCSETCGSNGKMHR 1816
C+K + + +H C KP C+ +C +W+Y EW+ CS +CG G+ R
Sbjct: 929 CMKYSIHEGQTVQVDDHYCGDQLKPPTQELCHGNCVFTRWHYSEWSQCSRSCG-GGERSR 987
Query: 1815 KSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWVYGHWSECSRSCDGGVKMRHAQC 1636
+SYC+++ R+ ++ C +E T CN CP W WSEC +C G K R C
Sbjct: 988 ESYCMNNFGHRLADNEC-QELSRVTRENCNEFSCPSWAASEWSECLVTCGKGTKQRQVWC 1046
Query: 1635 LDAADR--ETHTSRCGPAQTQEHCNEHACTWWQFGVWSDCSAKCGDGVQYRDANCTDRHR 1462
D + + ++ C H C WQ G W C+ CG G Q RD C +
Sbjct: 1047 QLNVDHLSDGFCNSSTKPESLSPCELHTCASWQVGPWGPCTTTCGHGYQMRDVKCVNELA 1106
Query: 1461 S-VLPEHRCLKMEKIITKPCHRESC------------------------PKYKLGEWSQC 1357
S VL + C + ++P R+SC +++ G W+ C
Sbjct: 1107 SAVLEDTECHE----ASRPSDRQSCVLTPCSFISKLETALLPTVLIKKMAQWRHGSWTPC 1162
Query: 1356 SVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNTDWSACSVS 1177
SVSC G +R VSC D S C RPA C C W+ DWS CS S
Sbjct: 1163 SVSCGRGTQARYVSCRDALDRIADESYCAHL-PRPAEIWDC-FTPCGEWQAGDWSPCSAS 1220
Query: 1176 CGIGHRERTTECIYREQSVDASFCGDTKMPETSQTCHLLPC------------------- 1054
CG G R C+ Q +D ++C P Q C L C
Sbjct: 1221 CGHGKTTRQVLCMNYHQPIDENYCDPEVRPLMEQECSLAACPPAHSHFPSSPVQPSYYLS 1280
Query: 1053 -----------------------TSWKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDE 943
W+ W CS +C G+Q R+V C + G
Sbjct: 1281 TNLPLTQKLEDNENQVVHPSVRGNQWRTGPWGQCSSSCSGGLQHRAVVC-QDENGQSAS- 1338
Query: 942 YFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATCGNGTQRRLLK 763
+CD ++P + C C +W G W CS TCG G + RL+
Sbjct: 1339 -YCDAASKPPELQQCGPGPCP---------------QWNYGNWGECSQTCGGGIKSRLVI 1382
Query: 762 CR-DHVRDLPDEYCNHLDKEVSTRNCRLRDCS---YWKMAEW 649
C+ + + L D C ++K S C + C W W
Sbjct: 1383 CQFPNGQILEDHNCEIVNKPPSVIQCHMHACPADVSWHQEPW 1424
Score = 262 bits (669), Expect = 7e-68
Identities = 161/581 (27%), Positives = 242/581 (40%), Gaps = 62/581 (10%)
Frame = -1
Query: 1701 YGHWSECSRSCDGGVKMRHAQCLDAADRETHTSR-CG----PAQTQEHCNEHACTWWQFG 1537
YG W C++ C G ++ R+ C+ +D + + C P+ + CN W
Sbjct: 851 YGPWEGCTKMCQG-LQRRNITCIHKSDHSVVSDKECDHLPLPSFVTQSCNTDCELRWHVI 909
Query: 1536 VWSDCSAKCGDGVQYRDANCT-----DRHRSVLPEHRCLKMEKIITKPCHRESC--PKYK 1378
S+CS++CG G + D +C + + +H C K T+ +C ++
Sbjct: 910 GKSECSSQCGQGYRTLDIHCMKYSIHEGQTVQVDDHYCGDQLKPPTQELCHGNCVFTRWH 969
Query: 1377 LGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNTD 1198
EWSQCS SC G SR C++ G + + C S + + CN +CP W ++
Sbjct: 970 YSEWSQCSRSCGGGERSRESYCMNNFGHRLADNECQELSR--VTRENCNEFSCPSWAASE 1027
Query: 1197 WSACSVSCGIGHRERTTECIYREQSVDASFCGDTKMPETSQTCHLLPCTSWKPSHWSPCS 1018
WS C V+CG G ++R C + FC + PE+ C L C SW+ W PC+
Sbjct: 1028 WSECLVTCGKGTKQRQVWCQLNVDHLSDGFCNSSTKPESLSPCELHTCASWQVGPWGPCT 1087
Query: 1017 VTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPP 838
TCG G Q R V C ++++ C +RP +++C C + KL+ + P
Sbjct: 1088 TTCGHGYQMRDVKCVNELASAVLEDTECHEASRPSDRQSCVLTPCS---FISKLETALLP 1144
Query: 837 -------IRWATGPWTACSATCGNGTQRRLLKCRDHVRDLPDE-YCNHLDKEVSTRNCRL 682
+W G WT CS +CG GTQ R + CRD + + DE YC HL + +C
Sbjct: 1145 TVLIKKMAQWRHGSWTPCSVSCGRGTQARYVSCRDALDRIADESYCAHLPRPAEIWDC-F 1203
Query: 681 RDCSYWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRL 502
C W+ +W C A+CG H + +R V C++ + + CD + RP + C L
Sbjct: 1204 TPCGEWQAGDWSPCSASCG-HGKTTRQVLCMNYHQP----IDENYCDPEVRPLMEQECSL 1258
Query: 501 EPCPKGEEHIGS-----------------------------------WIIGDWSKCSASC 427
CP H S W G W +CS+SC
Sbjct: 1259 AACPPAHSHFPSSPVQPSYYLSTNLPLTQKLEDNENQVVHPSVRGNQWRTGPWGQCSSSC 1318
Query: 426 GGGWXXXX------XXXXXXXCDETRKPKMFDKCNEELCPPLTNNSWQISPWTHCSVSCG 265
GG CD KP +C CP W W CS +CG
Sbjct: 1319 SGGLQHRAVVCQDENGQSASYCDAASKPPELQQCGPGPCP-----QWNYGNWGECSQTCG 1373
Query: 264 GGVQRRKIWCEDVLSGRKQDDIECSEI-KPREQRDCEMPPC 145
GG++ R + C+ +G+ +D C + KP C M C
Sbjct: 1374 GGIKSRLVICQ-FPNGQILEDHNCEIVNKPPSVIQCHMHAC 1413
Score = 231 bits (589), Expect = 1e-58
Identities = 158/622 (25%), Positives = 244/622 (38%), Gaps = 93/622 (14%)
Frame = -1
Query: 1872 YGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCP------ 1711
YG W C++ C G R C+ S+ V +++EC+ +P P
Sbjct: 851 YGPWEGCTKMC--QGLQRRNITCIHKSDHSV-----------VSDKECDHLPLPSFVTQS 897
Query: 1710 -------RWVYGHWSECSRSCDGGVKMRHAQCLDAADRETHTSR-----CGPA---QTQE 1576
RW SECS C G + C+ + E T + CG TQE
Sbjct: 898 CNTDCELRWHVIGKSECSSQCGQGYRTLDIHCMKYSIHEGQTVQVDDHYCGDQLKPPTQE 957
Query: 1575 HCNEHAC-TWWQFGVWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIITKPCHR 1399
C+ + T W + WS CS CG G + R++ C + L ++ C ++ ++ + C+
Sbjct: 958 LCHGNCVFTRWHYSEWSQCSRSCGGGERSRESYCMNNFGHRLADNECQELSRVTRENCNE 1017
Query: 1398 ESCPKYKLGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTC 1219
SCP + EWS+C V+C G R+V C N + C + S +P S C L TC
Sbjct: 1018 FSCPSWAASEWSECLVTCGKGTKQRQVWCQL-NVDHLSDGFCNS-STKPESLSPCELHTC 1075
Query: 1218 PFWRNTDWSACSVSCGIGHRERTTECIYREQS--VDASFCGDTKMPETSQTCHLLPCT-- 1051
W+ W C+ +CG G++ R +C+ S ++ + C + P Q+C L PC+
Sbjct: 1076 ASWQVGPWGPCTTTCGHGYQMRDVKCVNELASAVLEDTECHEASRPSDRQSCVLTPCSFI 1135
Query: 1050 -----------------SWKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNT 922
W+ W+PCSV+CG G Q R VSC R + I DE +C
Sbjct: 1136 SKLETALLPTVLIKKMAQWRHGSWTPCSVSCGRGTQARYVSC-RDALDRIADESYCAHLP 1194
Query: 921 RPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATCGNGTQRRLLKCRDHVRD 742
RP C P W G W+ CSA+CG+G R + C ++ +
Sbjct: 1195 RPAEIWDCF----------------TPCGEWQAGDWSPCSASCGHGKTTRQVLCMNYHQP 1238
Query: 741 LPDEYCNHLDKEVSTRNCRLRDC------------------------------------- 673
+ + YC+ + + + C L C
Sbjct: 1239 IDENYCDPEVRPLMEQECSLAACPPAHSHFPSSPVQPSYYLSTNLPLTQKLEDNENQVVH 1298
Query: 672 -----SYWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNC 508
+ W+ W +C ++C +Q R V C ++ G++ CD +P + C
Sbjct: 1299 PSVRGNQWRTGPWGQCSSSCSGGLQH-RAVVC--QDENGQSASY---CDAASKPPELQQC 1352
Query: 507 RLEPCPKGEEHIGSWIIGDWSKCSASCGGGWXX--------XXXXXXXXXCDETRKPKMF 352
PCP+ W G+W +CS +CGGG C+ KP
Sbjct: 1353 GPGPCPQ-------WNYGNWGECSQTCGGGIKSRLVICQFPNGQILEDHNCEIVNKPPSV 1405
Query: 351 DKCNEELCPPLTNNSWQISPWT 286
+C+ CP + SW PWT
Sbjct: 1406 IQCHMHACP--ADVSWHQEPWT 1425
Score = 209 bits (531), Expect = 7e-52
Identities = 151/547 (27%), Positives = 221/547 (39%), Gaps = 77/547 (14%)
Frame = -1
Query: 1554 TWWQFGVWSDCSAKCGDGVQYRDANCTDRH-RSVLPEHRC--LKMEKIITKPCHRESCPK 1384
TW +G W C+ C G+Q R+ C + SV+ + C L + +T+ C+ + +
Sbjct: 847 TWDPYGPWEGCTKMC-QGLQRRNITCIHKSDHSVVSDKECDHLPLPSFVTQSCNTDCELR 905
Query: 1383 YKLGEWSQCSVSCEDGWSSRRVSCVS-----GNGTEVDMSLCGTASDRPASHQTCNLGTC 1219
+ + S+CS C G+ + + C+ G +VD CG +P + + C+ G C
Sbjct: 906 WHVIGKSECSSQCGQGYRTLDIHCMKYSIHEGQTVQVDDHYCGDQL-KPPTQELCH-GNC 963
Query: 1218 PF--WRNTDWSACSVSCGIGHRERTTECI--YREQSVDASFCGDTKMPETSQTCHLLPCT 1051
F W ++WS CS SCG G R R + C+ + + D C + T + C+ C
Sbjct: 964 VFTRWHYSEWSQCSRSCGGGERSRESYCMNNFGHRLADNE-CQELSRV-TRENCNEFSCP 1021
Query: 1050 SWKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPR 871
SW S WS C VTCG G + R V C + + + FC+ +T+P CE TC
Sbjct: 1022 SWAASEWSECLVTCGKGTKQRQVWCQLNVDH--LSDGFCNSSTKPESLSPCELHTCAS-- 1077
Query: 870 VLQKLQADVPPIRWATGPWTACSATCGNGTQRRLLKCRDHVRD--LPDEYCNHLDKEVST 697
W GPW C+ TCG+G Q R +KC + + L D C+ +
Sbjct: 1078 -------------WQVGPWGPCTTTCGHGYQMRDVKCVNELASAVLEDTECHEASRPSDR 1124
Query: 696 RNCRLRDCSY-------------------WKMAEWEECPATCGTHVQQSRNVTCVSAEDG 574
++C L CS+ W+ W C +CG Q +R V+C A D
Sbjct: 1125 QSCVLTPCSFISKLETALLPTVLIKKMAQWRHGSWTPCSVSCGRGTQ-ARYVSCRDALD- 1182
Query: 573 GRTILKDVDCDVQKRPTSARNCRLEPCPKGEEHIGSWIIGDWSKCSASCGGGWXXXXXX- 397
I + C RP +C PC G W GDWS CSASCG G
Sbjct: 1183 --RIADESYCAHLPRPAEIWDC-FTPC-------GEWQAGDWSPCSASCGHGKTTRQVLC 1232
Query: 396 ------XXXXXCDETRKPKMFDKCNEELCPP----------------------------- 322
CD +P M +C+ CPP
Sbjct: 1233 MNYHQPIDENYCDPEVRPLMEQECSLAACPPAHSHFPSSPVQPSYYLSTNLPLTQKLEDN 1292
Query: 321 --------LTNNSWQISPWTHCSVSCGGGVQRRKIWCEDVLSGRKQDDIECSEIKPREQR 166
+ N W+ PW CS SC GG+Q R + C+D +G+ + + KP E +
Sbjct: 1293 ENQVVHPSVRGNQWRTGPWGQCSSSCSGGLQHRAVVCQDE-NGQSASYCDAAS-KPPELQ 1350
Query: 165 DCEMPPC 145
C PC
Sbjct: 1351 QCGPGPC 1357
Score = 181 bits (458), Expect = 2e-43
Identities = 130/457 (28%), Positives = 191/457 (41%), Gaps = 43/457 (9%)
Frame = -1
Query: 1374 GEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASH--------QTCNLGTC 1219
G W C+ C+ G R ++C+ + V SD+ H Q+CN
Sbjct: 852 GPWEGCTKMCQ-GLQRRNITCIHKSDHSV-------VSDKECDHLPLPSFVTQSCNTDCE 903
Query: 1218 PFWRNTDWSACSVSCGIGHRERTTEC----IYREQSV--DASFCGDTKMPETSQTCH-LL 1060
W S CS CG G+R C I+ Q+V D +CGD P T + CH
Sbjct: 904 LRWHVIGKSECSSQCGQGYRTLDIHCMKYSIHEGQTVQVDDHYCGDQLKPPTQELCHGNC 963
Query: 1059 PCTSWKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCD 880
T W S WS CS +CG G ++R C + D C +R ++ C + +C
Sbjct: 964 VFTRWHYSEWSQCSRSCGGGERSRESYCMNNFGHRLADNE-CQELSRVT-RENCNEFSCP 1021
Query: 879 GPRVLQKLQADVPPIRWATGPWTACSATCGNGTQRRLLKCRDHVRDLPDEYCNHLDKEVS 700
WA W+ C TCG GT++R + C+ +V L D +CN K S
Sbjct: 1022 S---------------WAASEWSECLVTCGKGTKQRQVWCQLNVDHLSDGFCNSSTKPES 1066
Query: 699 TRNCRLRDCSYWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTS 520
C L C+ W++ W C TCG H Q R+V CV+ + +L+D +C RP+
Sbjct: 1067 LSPCELHTCASWQVGPWGPCTTTCG-HGYQMRDVKCVN--ELASAVLEDTECHEASRPSD 1123
Query: 519 ARNCRLEPCP---KGE---------EHIGSWIIGDWSKCSASCGGGWXXXXXX---XXXX 385
++C L PC K E + + W G W+ CS SCG G
Sbjct: 1124 RQSCVLTPCSFISKLETALLPTVLIKKMAQWRHGSWTPCSVSCGRGTQARYVSCRDALDR 1183
Query: 384 XCDET------RKPKMFD---KCNEELCPPLTNNSWQISPWTHCSVSCGGGVQRRKIWCE 232
DE+ R +++D C E WQ W+ CS SCG G R++ C
Sbjct: 1184 IADESYCAHLPRPAEIWDCFTPCGE----------WQAGDWSPCSASCGHGKTTRQVLCM 1233
Query: 231 DVLSGRKQDDIECS-EIKPREQRDCEM---PPCRSHY 133
+ + D+ C E++P +++C + PP SH+
Sbjct: 1234 NY--HQPIDENYCDPEVRPLMEQECSLAACPPAHSHF 1268
Score = 179 bits (453), Expect = 8e-43
Identities = 122/473 (25%), Positives = 193/473 (40%), Gaps = 71/473 (15%)
Frame = -1
Query: 2232 WRVTDTWTECDRACRG-QQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRW 2056
W ++ W++C R+C G ++S++ C++ HR + D CQ + + + CN W
Sbjct: 968 WHYSE-WSQCSRSCGGGERSRESYCMNNFGHRLA-DNECQELSRVTREN--CNEFSCPSW 1023
Query: 2055 ITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYIDCSGRKW 1876
+ S C CG G K+++V C ++ D S+ C+ ++KP ++ C + W
Sbjct: 1024 AASEWSECLVTCGKGTKQRQVWC-QLNVDH---LSDGFCNSSTKPESLSPCELHTCA-SW 1078
Query: 1875 NYGEWTSCSETCGSNGKMHRKSYCVDD-SNRRVDESLCGREQKEATERECNRIPCP---- 1711
G W C+ TCG +G R CV++ ++ ++++ C + + + C PC
Sbjct: 1079 QVGPWGPCTTTCG-HGYQMRDVKCVNELASAVLEDTECHEASRPSDRQSCVLTPCSFISK 1137
Query: 1710 ---------------RWVYGHWSECSRSCDGGVKMRHAQCLDAADRETHTSRCG----PA 1588
+W +G W+ CS SC G + R+ C DA DR S C PA
Sbjct: 1138 LETALLPTVLIKKMAQWRHGSWTPCSVSCGRGTQARYVSCRDALDRIADESYCAHLPRPA 1197
Query: 1587 QTQEHCNEHACTWWQFGVWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIITKP 1408
+ + C WQ G WS CSA CG G R C + H+ + + ++ ++ +
Sbjct: 1198 EIWDCFTP--CGEWQAGDWSPCSASCGHGKTTRQVLCMNYHQPIDENYCDPEVRPLMEQE 1255
Query: 1407 CHRESCP------------------------------------------KYKLGEWSQCS 1354
C +CP +++ G W QCS
Sbjct: 1256 CSLAACPPAHSHFPSSPVQPSYYLSTNLPLTQKLEDNENQVVHPSVRGNQWRTGPWGQCS 1315
Query: 1353 VSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNTDWSACSVSC 1174
SC G R V C NG S C AS +P Q C G CP W +W CS +C
Sbjct: 1316 SSCSGGLQHRAVVCQDENGQSA--SYCDAAS-KPPELQQCGPGPCPQWNYGNWGECSQTC 1372
Query: 1173 GIGHRERTTECIY-REQSVDASFCGDTKMPETSQTCHLLPC---TSWKPSHWS 1027
G G + R C + Q ++ C P + CH+ C SW W+
Sbjct: 1373 GGGIKSRLVICQFPNGQILEDHNCEIVNKPPSVIQCHMHACPADVSWHQEPWT 1425
Score = 42.4 bits (98), Expect = 0.11
Identities = 23/70 (32%), Positives = 35/70 (49%), Gaps = 3/70 (4%)
Frame = -1
Query: 3129 QWGDWRSWGECSRTCGGGVQKGLRDCDSPKPR---NGGKYCVGQRERYRSCNTQECPWDT 2959
QW ++ +WGECS+TCGGG++ L C P + + V + C+ CP D
Sbjct: 1359 QW-NYGNWGECSQTCGGGIKSRLVICQFPNGQILEDHNCEIVNKPPSVIQCHMHACPADV 1417
Query: 2958 QPYREVQCSE 2929
++E SE
Sbjct: 1418 SWHQEPWTSE 1427
>gi|34857699|ref|XP_232202.2| similar to a disintegrin-like and
metalloprotease with thrombospondin type 1 motifs 9B
[Rattus norvegicus]
Length = 1783
Score = 837 bits (2162), Expect = 0.0
Identities = 491/1475 (33%), Positives = 698/1475 (47%), Gaps = 152/1475 (10%)
Frame = -1
Query: 4113 SWDHYVEVLVVADTKMYEYHGRSLEDYVLTLFSTVASIYRHQSLRASXXXXXXXXXXXKT 3934
S+ +VEV+VVAD +M YHG +L+ Y+LTL S VASIY+ S+
Sbjct: 174 SYPRFVEVMVVADHRMVLYHGSNLQHYILTLMSIVASIYKDSSIGNLINIVIVNLVVIHN 233
Query: 3933 ENAGPRITQNAQQTLQDFCRWQQYYNDPDDSSVQHHDVAILLTRKDICRSQGKCDTLGLA 3754
E GP I NAQ TL++FC+WQ N +QH D A+L+TR+DICR+Q KCDTLGLA
Sbjct: 234 EQEGPSINFNAQTTLKNFCQWQHSKNHL--GGIQH-DTAVLVTREDICRAQDKCDTLGLA 290
Query: 3753 ELGTMCDMQKSCAIIEDNGLSAAFTIAHELGHVFSIPHDDERKCSTYMPVNKVCKFQSTK 3574
ELGT+CD +SC+I ED+GLS AFTIAHELGHVF++PHDD K CK + K
Sbjct: 291 ELGTICDPYRSCSISEDSGLSTAFTIAHELGHVFNMPHDDSNK----------CKEEGVK 340
Query: 3573 FDKTQFQNNFHIMAPTLEYNTHPWSWSPCSAGMLERFLENNRGQTQCLFDQPVERRYYED 3394
+ H+MAPTL + T+PW WS CS + FL+ G +CL ++P R Y
Sbjct: 341 SPQ-------HVMAPTLNFYTNPWMWSKCSRKYITEFLDTGYG--ECLLNEPQSRTY--- 388
Query: 3393 VFVRDEPGKKYDAHQQCKFVFGPASELCPYMPTCRRLWCATFYGSQMGCRTQHMPWADGT 3214
PG Y+ ++QC+ +FGP S++CPY
Sbjct: 389 PLPSQLPGLLYNVNKQCELIFGPGSQVCPY------------------------------ 418
Query: 3213 PCDESRSMFCHHGACVRLAPESLTKIDGQWGDWRSWGECSRTCGGGVQKGLRDCDSPKPR 3034
M C G CV E IDG WG W +G CSRTCGGG++ +R+C+ P+P+
Sbjct: 419 -------MHCKFGFCVPKEMEG-PAIDGSWGSWSHFGACSRTCGGGIRTAIRECNRPEPK 470
Query: 3033 NGGKYCVGQRERYRSCNTQECPWDTQPYREVQCSEFNNKDIGIQGVASTNTHWVPKYANV 2854
NGG+YCVG+R +++SCNT+ CP + +RE QC+ F+ K I G+ + WVPKY+ +
Sbjct: 471 NGGRYCVGRRMKFKSCNTEPCPKHKRDFREEQCAYFDGKHFNINGLL-PSVRWVPKYSGI 529
Query: 2853 APNERCKLYCRLSGSAAFYLLRDKVVDGTPCDRNGDDICVAGACMPAGCDHQLHSTLRRD 2674
+RCKL+CR++G+ A+Y LRD+V+DGTPC ++ +DICV G C AGCDH L+S R+D
Sbjct: 530 LMKDRCKLFCRVAGNTAYYQLRDRVIDGTPCGQDTNDICVQGLCRQAGCDHILNSKARKD 589
Query: 2673 KCGVCGGDDSSCKVVKGTFNEQGTFGYNEVMKIPAGSANIDIRQKGYNNMKEDDNYLSLR 2494
KCG+CGGD+SSCK V GTFN +GYN V++IPAG+ ++D+RQ ++ EDDNYL+L
Sbjct: 590 KCGICGGDNSSCKTVAGTFNTV-HYGYNTVVRIPAGATSLDVRQHSFSGKSEDDNYLALS 648
Query: 2493 AANGEFLLNGHFQVSLARQQIAFQDTVLEYSGSDAIIERINGTGPIRSDIYVHVLSVGS- 2317
+ GEFLLNG F VS++++++ ++EYSGSD ++ER+N + I ++ + VLSVG
Sbjct: 649 NSRGEFLLNGDFVVSMSKREVRVGSAMIEYSGSDNVVERLNCSDRIEEELLLQVLSVGKL 708
Query: 2316 HPPDISYEYMTAAVPNAVIRPISSALYLWRVTDTWTECDRACRGQQSQKLMCLDMSTHRQ 2137
+ PD+ Y + N I S Y W W C + C+G++ +KL+C S
Sbjct: 709 YNPDVRYSF------NIPIEDRSQQFY-WNSHGPWQACSKPCQGERRRKLVCTRESDQLT 761
Query: 2136 SHDRNCQNVLKPKQATRMCNIDCSTRWITEDVSSCSAKCGSGQKRQRVSCVKME--GDRQ 1963
D+ C + +P T C DC RW S CSA+CG G + + C K +
Sbjct: 762 VSDQRCDRLPQPGPVTEACGTDCDLRWHIASKSECSAQCGLGYRTLDIHCAKYSRVDGKT 821
Query: 1962 TPASEHLCDRNSKPSDIASCYIDCSGRKWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRR 1783
+ C +PS+ C +CS W Y WT CS++C G R++ CV+ N
Sbjct: 822 EKVDDSFCGSQPRPSNQEKCSGECSTGGWRYSAWTECSKSC-DGGTQRRRAICVNTRNDV 880
Query: 1782 VDESLCGREQKEATERECNRIPCPRWVYGHWSE--------------------------- 1684
+D+S C +++K +R CN CP W G WSE
Sbjct: 881 LDDSKCAQQEKVIVQR-CNEFSCPHWKTGEWSEASNLNRVPLMGLEWSSSNMHPYLCLIC 939
Query: 1683 -----------CSRSCDGGVKMRHAQCLDAADRETHTSRCGP---AQTQEHCNEHACTWW 1546
C +C G K R C DR C P + + C + C W
Sbjct: 940 GHMINKLGAFPCLVTCGKGHKHRQVWCQFGEDR-LSDRMCDPEAKPEPMQMCQQPECAAW 998
Query: 1545 QFGVWSDCSAKCGDGVQYRDANC-TDRHRSVLPEHRC-LKMEKIITKPCHRESC------ 1390
Q G W CS CG G Q R C + SV+ ++ C T+ C SC
Sbjct: 999 QAGPWGQCSVTCGQGYQLRAVKCIMGTYMSVVDDNDCNAATRPTDTQDCELSSCHPSILT 1058
Query: 1389 ------------PKYKLGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPAS 1246
+++ G W+ CS +C G R VSC +G+ D S C T +P +
Sbjct: 1059 LEPRRHVHGVPRTQWRFGSWTPCSATCGKGTRMRYVSCRDEDGSVADESACATL-PKPVA 1117
Query: 1245 HQTCNLGTCPFWRNTDWSACSVSCGIGHRERTTECI-YREQSVDASFCGDTKMPETSQTC 1069
+ C++ C W+ DWS+CS++CG G R C+ Y + +D S C +PET Q C
Sbjct: 1118 KEECSVTPCGQWKALDWSSCSMTCGQGKATRQVVCVNYSDHVIDQSECDPDYIPETDQDC 1177
Query: 1068 HLLPC------------------------------TSWKPSHWSPCSVTCGSGIQTRSVS 979
+ PC W+ W CS TC G Q R V
Sbjct: 1178 SMSPCPQWTGSAYPFQNEDFRPRSDSPSRTHVLGGNQWRTGPWGACSSTCAGGSQRRVVV 1237
Query: 978 CTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTC----------------DGPR----VLQK 859
C + T D C +P ++ CE C G R V Q+
Sbjct: 1238 CQDENGYTATD---CVERIKPDEQRACESGPCPQWAYGSWGECTKLCGGGMRTRLVVCQR 1294
Query: 858 LQA-----------DVPPIR-------------WATGPWTACSATCGNGTQRRLLKC-RD 754
D PP R W+TGPW++CS +CG G + R + C
Sbjct: 1295 ANGDRFPDLSCEVLDKPPDREQCNTHACPQDAAWSTGPWSSCSVSCGRGHKHRNVYCLAK 1354
Query: 753 HVRDLPDEYCNHLDKEVSTRNCRLRDCSYWKMAEWEECPATCGTHVQQSRNVTCVSAEDG 574
L +YC HL K R R S + +C +CG VQQ R+V C + G
Sbjct: 1355 DGSHLESDYCKHLPK---PHGHRRRSPSAYLHPVSSQCSVSCGQGVQQ-RHVGC---QIG 1407
Query: 573 GRTILKDVDCDVQKRPTSARNCRLEPCPKGEEHIGSWIIGDWSKCSASCGGGWXXXXXXX 394
++ +C RP S R C+ PCP + +W W + W
Sbjct: 1408 THKTARESECSSYSRPESERVCQASPCP-----LYTWRAEQWQQ-----NRNWGPFRAYF 1457
Query: 393 XXXXCDETRKPKMFDKCN--------EELCPPLTNNSWQI----SPWTHCSVSCGGGVQR 250
TR + + + E+ L++ + + S C+ +CG G +
Sbjct: 1458 KFKSISCTRCRVILEFISLEQNNWNEEQFLGQLSDKIFMMFTAGSGEDLCTKTCGEGSRY 1517
Query: 249 RKIWCEDVLSGRKQDDIECSEIKPREQRDCEMPPC 145
R++ C S+ +P ++ C + PC
Sbjct: 1518 RQVVCVAEDQSEVHSAHCDSDQRPPDRESCSLQPC 1552
Score = 261 bits (668), Expect = 9e-68
Identities = 194/735 (26%), Positives = 295/735 (39%), Gaps = 78/735 (10%)
Frame = -1
Query: 2130 DRNCQNVLKPKQATRMCNIDCSTRWITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPAS 1951
DR C KP + +MC W CS CG G + + V C+ G +
Sbjct: 975 DRMCDPEAKP-EPMQMCQQPECAAWQAGPWGQCSVTCGQGYQLRAVKCIM--GTYMSVVD 1031
Query: 1950 EHLCDRNSKPSDIASCYIDCSG-----------------RKWNYGEWTSCSETCGSNGKM 1822
++ C+ ++P+D C + +W +G WT CS TCG +M
Sbjct: 1032 DNDCNAATRPTDTQDCELSSCHPSILTLEPRRHVHGVPRTQWRFGSWTPCSATCGKGTRM 1091
Query: 1821 HRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWVYGHWSECSRSCDGGVKMRHA 1642
S C D+ DES C K + EC+ PC +W WS CS +C G R
Sbjct: 1092 RYVS-CRDEDGSVADESACATLPKPVAKEECSVTPCGQWKALDWSSCSMTCGQGKATRQV 1150
Query: 1641 QCLDAADRETHTSRCGP---AQTQEHCNEHACT-W------------------------- 1549
C++ +D S C P +T + C+ C W
Sbjct: 1151 VCVNYSDHVIDQSECDPDYIPETDQDCSMSPCPQWTGSAYPFQNEDFRPRSDSPSRTHVL 1210
Query: 1548 ----WQFGVWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCL-KMEKIITKPCHRESCPK 1384
W+ G W CS+ C G Q R C D + + C+ +++ + C CP+
Sbjct: 1211 GGNQWRTGPWGACSSTCAGGSQRRVVVCQDENGYTATD--CVERIKPDEQRACESGPCPQ 1268
Query: 1383 YKLGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCP---F 1213
+ G W +C+ C G +R V C NG C D+P + CN CP
Sbjct: 1269 WAYGSWGECTKLCGGGMRTRLVVCQRANGDRFPDLSCEVL-DKPPDREQCNTHACPQDAA 1327
Query: 1212 WRNTDWSACSVSCGIGHRERTTECIYREQS-VDASFCGDTKMPE----TSQTCHLLPCTS 1048
W WS+CSVSCG GH+ R C+ ++ S +++ +C P S + +L P +S
Sbjct: 1328 WSTGPWSSCSVSCGRGHKHRNVYCLAKDGSHLESDYCKHLPKPHGHRRRSPSAYLHPVSS 1387
Query: 1047 WKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRV 868
CSV+CG G+Q R V C G+ T E C +RP ++ C+ C P
Sbjct: 1388 -------QCSVSCGQGVQQRHVGCQIGTHKT-ARESECSSYSRPESERVCQASPC--PLY 1437
Query: 867 LQKLQADVPPIRWATGPWTAC----SATCGNGTQRRLLKCRDHVRDLPDEYCNHLDKEVS 700
+ + W GP+ A S +C +CR + + E N +++
Sbjct: 1438 TWRAEQWQQNRNW--GPFRAYFKFKSISC--------TRCRVILEFISLEQNNWNEEQFL 1487
Query: 699 TRNCRLRDCSYWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTS 520
+ + + + C TCG + R V CV AED ++ + CD +RP
Sbjct: 1488 GQLSDKIFMMFTAGSGEDLCTKTCGEG-SRYRQVVCV-AED--QSEVHSAHCDSDQRPPD 1543
Query: 519 ARNCRLEPCPKGEEHIGSWIIGDWSKCSASCGGGWXXXXXXXXXXXCDETR--------- 367
+C L+PC E++ WI G+WS+CS +CG G+ +
Sbjct: 1544 RESCSLQPC----EYV--WITGEWSECSVTCGKGYRQRLVSCSEIYTGKENYEYSYQTTV 1597
Query: 366 -----KPKMFDKCNEELCPPLTNNSWQISPWTHCSVSCGGGVQRRKIWCEDVLSGRKQDD 202
+P C CP + +W++ W CSVSCG GV R + C L+ Q
Sbjct: 1598 NCPGTQPPSVHPCYLRDCP--VSATWRVGNWGSCSVSCGMGVMHRSVQC---LTNEDQPS 1652
Query: 201 IEC-SEIKPREQRDC 160
C ++IKP E++ C
Sbjct: 1653 HLCPTDIKPEERKTC 1667
Score = 213 bits (543), Expect = 3e-53
Identities = 175/646 (27%), Positives = 247/646 (38%), Gaps = 69/646 (10%)
Frame = -1
Query: 2232 WRVTDTWTECDRAC-RGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRW 2056
WR +WT C C +G + + + C D + + C + KP A C++ +W
Sbjct: 1073 WRF-GSWTPCSATCGKGTRMRYVSCRD-EDGSVADESACATLPKPV-AKEECSVTPCGQW 1129
Query: 2055 ITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNS-KPSDIASCYIDCS--- 1888
D SSCS CG G+ ++V CV S+H+ D++ P I DCS
Sbjct: 1130 KALDWSSCSMTCGQGKATRQVVCVNY--------SDHVIDQSECDPDYIPETDQDCSMSP 1181
Query: 1887 ------------------------------GRKWNYGEWTSCSETCGSNGKMHRKSYCVD 1798
G +W G W +CS TC + G R C D
Sbjct: 1182 CPQWTGSAYPFQNEDFRPRSDSPSRTHVLGGNQWRTGPWGACSSTC-AGGSQRRVVVCQD 1240
Query: 1797 DSNRRVDESLCGREQKEATERECNRIPCPRWVYGHWSECSRSCDGGVKMRHAQCLDAADR 1618
++ + C K +R C PCP+W YG W EC++ C GG++ R C A
Sbjct: 1241 ENGYTATD--CVERIKPDEQRACESGPCPQWAYGSWGECTKLCGGGMRTRLVVCQRANGD 1298
Query: 1617 ETHTSRC---GPAQTQEHCNEHACTW---WQFGVWSDCSAKCGDGVQYRDANCTDRHRSV 1456
C +E CN HAC W G WS CS CG G ++R+ C + S
Sbjct: 1299 RFPDLSCEVLDKPPDREQCNTHACPQDAAWSTGPWSSCSVSCGRGHKHRNVYCLAKDGSH 1358
Query: 1455 LPEHRCLKMEKIITKPC-HRESCPK-YKLGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDM 1282
L C K + KP HR P Y SQCSVSC G R V C G
Sbjct: 1359 LESDYC----KHLPKPHGHRRRSPSAYLHPVSSQCSVSCGQGVQQRHVGCQIGTHKTARE 1414
Query: 1281 SLCGTASDRPASHQTCNLGTCPF--WRNTDWSAC-------------SVSCGIGHRERTT 1147
S C + S RP S + C CP WR W S+SC T
Sbjct: 1415 SECSSYS-RPESERVCQASPCPLYTWRAEQWQQNRNWGPFRAYFKFKSISC--------T 1465
Query: 1146 ECIYREQSVDASFCGDTKMPETSQTCHLLPCTSWKPSHWSPCSVTCGSGIQTRSVSCTRG 967
C + + + Q + S C+ TCG G + R V C
Sbjct: 1466 RCRVILEFISLEQNNWNEEQFLGQLSDKIFMMFTAGSGEDLCTKTCGEGSRYRQVVCVAE 1525
Query: 966 SEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATCGN 787
+ + + CD + RP +++C C+ W TG W+ CS TCG
Sbjct: 1526 DQSEVHSAH-CDSDQRPPDRESCSLQPCE--------------YVWITGEWSECSVTCGK 1570
Query: 786 GTQRRLLKCRDHVRDLPD-EYCNHL------DKEVSTRNCRLRDC---SYWKMAEWEECP 637
G ++RL+ C + + EY + S C LRDC + W++ W C
Sbjct: 1571 GYRQRLVSCSEIYTGKENYEYSYQTTVNCPGTQPPSVHPCYLRDCPVSATWRVGNWGSCS 1630
Query: 636 ATCGTHVQQSRNVTCVSAEDGGRTIL-KDVDCDVQKRPTSARNCRL 502
+CG V R+V C++ ED + D+ + +K + NC L
Sbjct: 1631 VSCGMGVMH-RSVQCLTNEDQPSHLCPTDIKPEERKTCHNVYNCEL 1675
Score = 135 bits (340), Expect = 1e-29
Identities = 123/471 (26%), Positives = 180/471 (38%), Gaps = 82/471 (17%)
Frame = -1
Query: 2232 WRVTDTWTECDRACRG-QQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRW 2056
WR T W C C G Q + ++C D + + + +C +KP + R C +W
Sbjct: 1215 WR-TGPWGACSSTCAGGSQRRVVVCQDENGYTAT---DCVERIKPDEQ-RACESGPCPQW 1269
Query: 2055 ITEDVSSCSAKCGSGQKRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASCYIDCSGRK- 1879
C+ CG G + + V C + GDR S C+ KP D C +
Sbjct: 1270 AYGSWGECTKLCGGGMRTRLVVCQRANGDRFPDLS---CEVLDKPPDREQCNTHACPQDA 1326
Query: 1878 -WNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWV 1702
W+ G W+SCS +CG G HR YC+ ++ C K R R P ++
Sbjct: 1327 AWSTGPWSSCSVSCG-RGHKHRNVYCLAKDGSHLESDYCKHLPKPHGHRR--RSPSA-YL 1382
Query: 1701 YGHWSECSRSCDGGVKM-------------RHAQCLD----AADRETHTSRC-------- 1597
+ S+CS SC GV+ R ++C ++R S C
Sbjct: 1383 HPVSSQCSVSCGQGVQQRHVGCQIGTHKTARESECSSYSRPESERVCQASPCPLYTWRAE 1442
Query: 1596 --------GPAQTQEHCNEHACT---------------WWQ---FGVWSD---------- 1525
GP + +CT W + G SD
Sbjct: 1443 QWQQNRNWGPFRAYFKFKSISCTRCRVILEFISLEQNNWNEEQFLGQLSDKIFMMFTAGS 1502
Query: 1524 ----CSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIITKPCHRESCPK------YKL 1375
C+ CG+G +YR C +S + C ++ P RESC +
Sbjct: 1503 GEDLCTKTCGEGSRYRQVVCVAEDQSEVHSAHCDSDQR----PPDRESCSLQPCEYVWIT 1558
Query: 1374 GEWSQCSVSCEDGWSSRRVSC--VSGNGTEVDMSLCGTAS---DRPASHQTCNLGTCPF- 1213
GEWS+CSV+C G+ R VSC + + S T + +P S C L CP
Sbjct: 1559 GEWSECSVTCGKGYRQRLVSCSEIYTGKENYEYSYQTTVNCPGTQPPSVHPCYLRDCPVS 1618
Query: 1212 --WRNTDWSACSVSCGIGHRERTTECIYREQSVDASFCGDTKMPETSQTCH 1066
WR +W +CSVSCG+G R+ +C+ E + C PE +TCH
Sbjct: 1619 ATWRVGNWGSCSVSCGMGVMHRSVQCLTNEDQ-PSHLCPTDIKPEERKTCH 1668
Score = 87.0 bits (214), Expect = 4e-15
Identities = 113/506 (22%), Positives = 170/506 (33%), Gaps = 86/506 (16%)
Frame = -1
Query: 2364 GPIRSDIYVHVLSVGSHPPDISYEYMTAAVPNAVIRPISSALYLWRVTDTWTECDRAC-R 2188
G +R+ + V + G PD+S E + + T W+ C +C R
Sbjct: 1283 GGMRTRLVVCQRANGDRFPDLSCEVLDKPPDREQCNTHACPQDAAWSTGPWSSCSVSCGR 1342
Query: 2187 GQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRWITEDVSSCSAKCGSGQ 2008
G + + + CL D C+++ KP R + ++ S CS CG G
Sbjct: 1343 GHKHRNVYCLAKDGSHLESDY-CKHLPKPHGHRRRS----PSAYLHPVSSQCSVSCGQGV 1397
Query: 2007 KRQRVSCVKMEGDRQTPASEHLCDRNSKPSDIASC------------------------- 1903
+++ V C G +T A E C S+P C
Sbjct: 1398 QQRHVGC--QIGTHKT-ARESECSSYSRPESERVCQASPCPLYTWRAEQWQQNRNWGPFR 1454
Query: 1902 ------------------YIDCSGRKWNYGEWTS------------------CSETCGSN 1831
+I WN ++ C++TCG
Sbjct: 1455 AYFKFKSISCTRCRVILEFISLEQNNWNEEQFLGQLSDKIFMMFTAGSGEDLCTKTCGE- 1513
Query: 1830 GKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPR-WVYGHWSECSRSCDGGVK 1654
G +R+ CV + V + C +Q+ C+ PC W+ G WSECS +C G +
Sbjct: 1514 GSRYRQVVCVAEDQSEVHSAHCDSDQRPPDRESCSLQPCEYVWITGEWSECSVTCGKGYR 1573
Query: 1653 MRHAQCLDA-ADRETH------TSRCGPAQ--TQEHCNEHAC---TWWQFGVWSDCSAKC 1510
R C + +E + T C Q + C C W+ G W CS C
Sbjct: 1574 QRLVSCSEIYTGKENYEYSYQTTVNCPGTQPPSVHPCYLRDCPVSATWRVGNWGSCSVSC 1633
Query: 1509 GDGVQYRDANCTDRHRSVLPEHRC---LKMEKIITKPCHR-------ESCPKYKLGEWSQ 1360
G GV +R C P H C +K E+ K CH ++C + K + +
Sbjct: 1634 GMGVMHRSVQCLTNEDQ--PSHLCPTDIKPEE--RKTCHNVYNCELPQNCKEVK--KLNS 1687
Query: 1359 CSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCPFWRNTDWSACSV 1180
SV E + R G + + G SD P + T G + +
Sbjct: 1688 ASVDGEYFLAVR--------GKPLKVFCAGMHSDYPKEYVTLAHG----------DSENF 1729
Query: 1179 SCGIGHR-ERTTECIYREQSVDASFC 1105
S GHR TEC Y D C
Sbjct: 1730 SEVYGHRLHNPTECPYNGSRRDDCHC 1755
>gi|33624885|ref|NP_064634.2| a disintegrin and metalloproteinase with
thrombospondin motifs 9 isoform 3 preproprotein [Homo
sapiens]
Length = 1072
Score = 753 bits (1945), Expect = 0.0
Identities = 388/957 (40%), Positives = 547/957 (56%), Gaps = 39/957 (4%)
Frame = -1
Query: 4437 CIYRAHVKGVHQHS-IVNLCDSEDGLYGMLALPSGIHTVEPIISGNGTEHDGASRHRQHL 4261
C Y+ +V +H+ +++LC G+ G G + +EP+ S + E D +++ H+
Sbjct: 150 CFYKGYVNTNSEHTAVISLCS---GMLGTFRSHDGDYFIEPLQSMDEQE-DEEEQNKPHI 205
Query: 4260 V-RKFDPMHFKSF--------DHLNSTSVNETETTVATWQDQWE---------------- 4156
+ R+ P S +H N S ++ +T W ++
Sbjct: 206 IYRRSAPQREPSTGRHACDTSEHKNRHSKDKKKTRARKWGERINLAGDVAALNSGLATEA 265
Query: 4155 --------DVIERKARSRRAAN--SWDHYVEVLVVADTKMYEYHGRSLEDYVLTLFSTVA 4006
D K RR S+ +VEVLVVAD +M YHG +L+ Y+LTL S VA
Sbjct: 266 FSAYGNKTDNTREKRTHRRTKRFLSYPRFVEVLVVADNRMVSYHGENLQHYILTLMSIVA 325
Query: 4005 SIYRHQSLRASXXXXXXXXXXXKTENAGPRITQNAQQTLQDFCRWQQYYNDPDDSSVQHH 3826
SIY+ S+ E GP I+ NAQ TL++FC+WQ N P HH
Sbjct: 326 SIYKDPSIGNLINIVIVNLIVIHNEQDGPSISFNAQTTLKNFCQWQHSKNSPGGI---HH 382
Query: 3825 DVAILLTRKDICRSQGKCDTLGLAELGTMCDMQKSCAIIEDNGLSAAFTIAHELGHVFSI 3646
D A+LLTR+DICR+ KCDTLGLAELGT+CD +SC+I ED+GLS AFTIAHELGHVF++
Sbjct: 383 DTAVLLTRQDICRAHDKCDTLGLAELGTICDPYRSCSISEDSGLSTAFTIAHELGHVFNM 442
Query: 3645 PHDDERKCSTYMPVNKVCKFQSTKFDKTQFQNNFHIMAPTLEYNTHPWSWSPCSAGMLER 3466
PHDD KC K + K + H+MAPTL + T+PW WS CS +
Sbjct: 443 PHDDNNKC----------KEEGVKSPQ-------HVMAPTLNFYTNPWMWSKCSRKYITE 485
Query: 3465 FLENNRGQTQCLFDQPVERRYYEDVFVRDEPGKKYDAHQQCKFVFGPASELCPYMPTCRR 3286
FL+ G+ CL ++P R Y V + PG Y+ ++QC+ +FGP S++CPYM CRR
Sbjct: 486 FLDTGYGE--CLLNEPESRPYPLPVQL---PGILYNVNKQCELIFGPGSQVCPYMMQCRR 540
Query: 3285 LWCATFYGSQMGCRTQHMPWADGTPCDESRSMFCHHGACVRLAPESLTKIDGQWGDWRSW 3106
LWC G GCRTQH PWADGT C+ + C +G CV + + DG WG W +
Sbjct: 541 LWCNNVNGVHKGCRTQHTPWADGTECEPGKH--CKYGFCVPKEMD-VPVTDGSWGSWSPF 597
Query: 3105 GECSRTCGGGVQKGLRDCDSPKPRNGGKYCVGQRERYRSCNTQECPWDTQPYREVQCSEF 2926
G CSRTCGGG++ +R+C+ P+P+NGGKYCVG+R +++SCNT+ C + +R+ QC+ F
Sbjct: 598 GTCSRTCGGGIKTAIRECNRPEPKNGGKYCVGRRMKFKSCNTEPCLKQKRDFRDEQCAHF 657
Query: 2925 NNKDIGIQGVASTNTHWVPKYANVAPNERCKLYCRLSGSAAFYLLRDKVVDGTPCDRNGD 2746
+ K I G+ N WVPKY+ + +RCKL+CR++G+ A+Y LRD+V+DGTPC ++ +
Sbjct: 658 DGKHFNINGLLP-NVRWVPKYSGILMKDRCKLFCRVAGNTAYYQLRDRVIDGTPCGQDTN 716
Query: 2745 DICVAGACMPAGCDHQLHSTLRRDKCGVCGGDDSSCKVVKGTFNEQGTFGYNEVMKIPAG 2566
DICV G C AGCDH L+S RRDKCGVCGGD+SSCK V GTFN +GYN V++IPAG
Sbjct: 717 DICVQGLCRQAGCDHVLNSKARRDKCGVCGGDNSSCKTVAGTFNTV-HYGYNTVVRIPAG 775
Query: 2565 SANIDIRQKGYNNMKEDDNYLSLRAANGEFLLNGHFQVSLARQQIAFQDTVLEYSGSDAI 2386
+ NID+RQ ++ +DDNYL+L ++ GEFLLNG+F V++A+++I + V+EYSGS+
Sbjct: 776 ATNIDVRQHSFSGETDDDNYLALSSSKGEFLLNGNFVVTMAKREIRIGNAVVEYSGSETA 835
Query: 2385 IERINGTGPIRSDIYVHVLSVGS-HPPDISYEYMTAAVPNAVIRPISSALYLWRVTDTWT 2209
+ERIN T I ++ + VLSVG + PD+ Y + N I Y W W
Sbjct: 836 VERINSTDRIEQELLLQVLSVGKLYNPDVRYSF------NIPIEDKPQQFY-WNSHGPWQ 888
Query: 2208 ECDRACRGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRWITEDVSSCS 2029
C + C+G++ +KL+C S D+ C + +P T C DC RW S CS
Sbjct: 889 ACSKPCQGERKRKLVCTRESDQLTVSDQRCDRLPQPGHITEPCGTDCDLRWHVASRSECS 948
Query: 2028 AKCGSGQKRQRVSCVKME--GDRQTPASEHLCDRNSKPSDIASCYIDCSGRKWNYGEWTS 1855
A+CG G + + C K + + C + KPS+ C +C+ W Y WT
Sbjct: 949 AQCGLGYRTLDIYCAKYSRLDGKTEKVDDGFCSSHPKPSNREKCSGECNTGGWRYSAWTE 1008
Query: 1854 CSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWVYGHWSE 1684
CS++C G R++ CV+ N +D+S C ++K +R C+ PCP+W G WSE
Sbjct: 1009 CSKSC-DGGTQRRRAICVNTRNDVLDDSKCTHQEKVTIQR-CSEFPCPQWKSGDWSE 1063
Score = 89.7 bits (221), Expect = 6e-16
Identities = 53/196 (27%), Positives = 82/196 (41%), Gaps = 23/196 (11%)
Frame = -1
Query: 1878 WN-YGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCP--- 1711
WN +G W +CS+ C G+ RK C +S +Q +++ C+R+P P
Sbjct: 881 WNSHGPWQACSKPC--QGERKRKLVCTRES-----------DQLTVSDQRCDRLPQPGHI 927
Query: 1710 ----------RWVYGHWSECSRSCDGGVKMRHAQC-----LDAADRETHTSRCG----PA 1588
RW SECS C G + C LD + C P+
Sbjct: 928 TEPCGTDCDLRWHVASRSECSAQCGLGYRTLDIYCAKYSRLDGKTEKVDDGFCSSHPKPS 987
Query: 1587 QTQEHCNEHACTWWQFGVWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIITKP 1408
++ E W++ W++CS C G Q R A C + VL + +C EK+ +
Sbjct: 988 NREKCSGECNTGGWRYSAWTECSKSCDGGTQRRRAICVNTRNDVLDDSKCTHQEKVTIQR 1047
Query: 1407 CHRESCPKYKLGEWSQ 1360
C CP++K G+WS+
Sbjct: 1048 CSEFPCPQWKSGDWSE 1063
Score = 81.3 bits (199), Expect = 2e-13
Identities = 57/196 (29%), Positives = 79/196 (40%), Gaps = 11/196 (5%)
Frame = -1
Query: 1197 WSACSVSCGIGHRERTTECIYREQSVDASFCGDTKMPETSQTCHLL-PCTS-----WKPS 1036
W ACS C G R+R C + S D + Q H+ PC + W +
Sbjct: 887 WQACSKPCQ-GERKRKLVCTRESDQLTVS---DQRCDRLPQPGHITEPCGTDCDLRWHVA 942
Query: 1035 HWSPCSVTCGSGIQTRSVSCTRGS----EGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRV 868
S CS CG G +T + C + S + VD+ FC + +P ++ C + G
Sbjct: 943 SRSECSAQCGLGYRTLDIYCAKYSRLDGKTEKVDDGFCSSHPKPSNREKCSGECNTGG-- 1000
Query: 867 LQKLQADVPPIRWATGPWTACSATCGNGTQRRLLKCRDHVRD-LPDEYCNHLDKEVSTRN 691
W WT CS +C GTQRR C + D L D C H +K V+ +
Sbjct: 1001 ------------WRYSAWTECSKSCDGGTQRRRAICVNTRNDVLDDSKCTHQEK-VTIQR 1047
Query: 690 CRLRDCSYWKMAEWEE 643
C C WK +W E
Sbjct: 1048 CSEFPCPQWKSGDWSE 1063
Score = 77.4 bits (189), Expect = 3e-12
Identities = 53/186 (28%), Positives = 85/186 (45%), Gaps = 11/186 (5%)
Frame = -1
Query: 1551 WWQFGVWSDCSAKCGDGVQYRDANCT-DRHRSVLPEHRCLKMEKI--ITKPCHRESCPKY 1381
W G W CS C G + R CT + + + + RC ++ + IT+PC + ++
Sbjct: 881 WNSHGPWQACSKPC-QGERKRKLVCTRESDQLTVSDQRCDRLPQPGHITEPCGTDCDLRW 939
Query: 1380 KLGEWSQCSVSCEDGWSSRRVSC-----VSGNGTEVDMSLCGTASDRPASHQTCNLGTCP 1216
+ S+CS C G+ + + C + G +VD C ++ +P++ + C+ G C
Sbjct: 940 HVASRSECSAQCGLGYRTLDIYCAKYSRLDGKTEKVDDGFC-SSHPKPSNREKCS-GECN 997
Query: 1215 F--WRNTDWSACSVSCGIGHRERTTECI-YREQSVDASFCGDTKMPETSQTCHLLPCTSW 1045
WR + W+ CS SC G + R C+ R +D S C + T Q C PC W
Sbjct: 998 TGGWRYSAWTECSKSCDGGTQRRRAICVNTRNDVLDDSKCTHQE-KVTIQRCSEFPCPQW 1056
Query: 1044 KPSHWS 1027
K WS
Sbjct: 1057 KSGDWS 1062
Score = 77.0 bits (188), Expect = 4e-12
Identities = 56/188 (29%), Positives = 77/188 (40%), Gaps = 18/188 (9%)
Frame = -1
Query: 1701 YGHWSECSRSCDGGVKMRHAQCLDAADRETHTS-RCG----PAQTQEHCNEHACTWWQFG 1537
+G W CS+ C G K R C +D+ T + RC P E C W
Sbjct: 884 HGPWQACSKPCQGERK-RKLVCTRESDQLTVSDQRCDRLPQPGHITEPCGTDCDLRWHVA 942
Query: 1536 VWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIIT-------KPCHRESCPK-- 1384
S+CSA+CG G + D C R K EK+ KP +RE C
Sbjct: 943 SRSECSAQCGLGYRTLDIYCAKYSRLDG------KTEKVDDGFCSSHPKPSNREKCSGEC 996
Query: 1383 ----YKLGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCP 1216
++ W++CS SC+ G RR CV+ +D S C + Q C+ CP
Sbjct: 997 NTGGWRYSAWTECSKSCDGGTQRRRAICVNTRNDVLDDSKC--THQEKVTIQRCSEFPCP 1054
Query: 1215 FWRNTDWS 1192
W++ DWS
Sbjct: 1055 QWKSGDWS 1062
Score = 70.1 bits (170), Expect = 5e-10
Identities = 53/196 (27%), Positives = 80/196 (40%), Gaps = 15/196 (7%)
Frame = -1
Query: 822 GPWTACSATCGNGTQRRLLKCRDHVR-DLPDEYCNHLDK-----EVSTRNCRLRDCSYWK 661
GPW ACS C +R+L+ R+ + + D+ C+ L + E +C LR W
Sbjct: 885 GPWQACSKPCQGERKRKLVCTRESDQLTVSDQRCDRLPQPGHITEPCGTDCDLR----WH 940
Query: 660 MAEWEECPATCGTHVQQSRNVTCV--SAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPK 487
+A EC A CG ++ ++ C S DG + D C +P++ C
Sbjct: 941 VASRSECSAQCGLG-YRTLDIYCAKYSRLDGKTEKVDDGFCSSHPKPSNREKC------S 993
Query: 486 GEEHIGSWIIGDWSKCSASCGGGWXXXXXXXXXXXCDE------TRKPKM-FDKCNEELC 328
GE + G W W++CS SC GG D T + K+ +C+E C
Sbjct: 994 GECNTGGWRYSAWTECSKSCDGGTQRRRAICVNTRNDVLDDSKCTHQEKVTIQRCSEFPC 1053
Query: 327 PPLTNNSWQISPWTHC 280
P + W W C
Sbjct: 1054 PQWKSGDWSEVRWEGC 1069
Score = 63.9 bits (154), Expect = 4e-08
Identities = 53/189 (28%), Positives = 73/189 (38%), Gaps = 14/189 (7%)
Frame = -1
Query: 669 YWKM-AEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPC 493
YW W+ C C ++ R + C D + + D CD +P EPC
Sbjct: 880 YWNSHGPWQACSKPC--QGERKRKLVCTRESD--QLTVSDQRCDRLPQPGHIT----EPC 931
Query: 492 PKGEEHIGSWIIGDWSKCSASCGGGWXXXXXXXXXXXCDETRKPKMFD--------KCNE 337
G + W + S+CSA CG G+ + + K+ D N
Sbjct: 932 --GTDCDLRWHVASRSECSAQCGLGYRTLDIYCAKYSRLDGKTEKVDDGFCSSHPKPSNR 989
Query: 336 ELCPPLTNNS-WQISPWTHCSVSCGGGVQRRKIWC----EDVLSGRKQDDIECSEIKPRE 172
E C N W+ S WT CS SC GG QRR+ C DVL DD +C+ +
Sbjct: 990 EKCSGECNTGGWRYSAWTECSKSCDGGTQRRRAICVNTRNDVL-----DDSKCTHQEKVT 1044
Query: 171 QRDCEMPPC 145
+ C PC
Sbjct: 1045 IQRCSEFPC 1053
>gi|9581879|gb|AAF89106.1| disintegrin metalloproteinase with
thrombospondin repeats [Homo sapiens]
Length = 1072
Score = 751 bits (1939), Expect = 0.0
Identities = 387/957 (40%), Positives = 546/957 (56%), Gaps = 39/957 (4%)
Frame = -1
Query: 4437 CIYRAHVKGVHQHS-IVNLCDSEDGLYGMLALPSGIHTVEPIISGNGTEHDGASRHRQHL 4261
C Y+ +V +H+ +++LC G+ G G + +EP+ S + E D +++ H+
Sbjct: 150 CFYKGYVNTNSEHTAVISLCS---GMLGTFRSHDGDYFIEPLQSMDEQE-DEEEQNKPHI 205
Query: 4260 V-RKFDPMHFKSF--------DHLNSTSVNETETTVATWQDQWE---------------- 4156
+ R+ P S +H N S ++ +T W ++
Sbjct: 206 IYRRSAPQREPSTGRHACDTSEHKNRHSKDKKKTRARKWGERINLAGDVAALNSGLATEA 265
Query: 4155 --------DVIERKARSRRAAN--SWDHYVEVLVVADTKMYEYHGRSLEDYVLTLFSTVA 4006
D K RR S+ +VEVLVVAD +M YHG +L+ Y+LTL S VA
Sbjct: 266 FSAYGNKTDNTREKRTHRRTKRFLSYPRFVEVLVVADNRMVSYHGENLQHYILTLMSIVA 325
Query: 4005 SIYRHQSLRASXXXXXXXXXXXKTENAGPRITQNAQQTLQDFCRWQQYYNDPDDSSVQHH 3826
SIY+ S+ E GP I+ NAQ TL++ C+WQ N P HH
Sbjct: 326 SIYKDPSIGNLINIVIVNLIVIHNEQDGPSISFNAQTTLKNLCQWQHSKNSPGGI---HH 382
Query: 3825 DVAILLTRKDICRSQGKCDTLGLAELGTMCDMQKSCAIIEDNGLSAAFTIAHELGHVFSI 3646
D A+LLTR+DICR+ KCDTLGLAELGT+CD +SC+I ED+GLS AFTIAHELGHVF++
Sbjct: 383 DTAVLLTRQDICRAHDKCDTLGLAELGTICDPYRSCSISEDSGLSTAFTIAHELGHVFNM 442
Query: 3645 PHDDERKCSTYMPVNKVCKFQSTKFDKTQFQNNFHIMAPTLEYNTHPWSWSPCSAGMLER 3466
PHDD KC K + K + H+MAPTL + T+PW WS CS +
Sbjct: 443 PHDDNNKC----------KEEGVKSPQ-------HVMAPTLNFYTNPWMWSKCSRKYITE 485
Query: 3465 FLENNRGQTQCLFDQPVERRYYEDVFVRDEPGKKYDAHQQCKFVFGPASELCPYMPTCRR 3286
FL+ G+ CL ++P R Y V + PG Y+ ++QC+ +FGP S++CPYM CRR
Sbjct: 486 FLDTGYGE--CLLNEPESRPYPLPVQL---PGILYNVNKQCELIFGPGSQVCPYMMQCRR 540
Query: 3285 LWCATFYGSQMGCRTQHMPWADGTPCDESRSMFCHHGACVRLAPESLTKIDGQWGDWRSW 3106
LWC G GCRTQH PWADGT C+ + C +G CV + + DG WG W +
Sbjct: 541 LWCNNVNGVHKGCRTQHTPWADGTECEPGKH--CKYGFCVPKEMD-VPVTDGSWGSWSPF 597
Query: 3105 GECSRTCGGGVQKGLRDCDSPKPRNGGKYCVGQRERYRSCNTQECPWDTQPYREVQCSEF 2926
G CSRTCGGG++ +R+C+ P+P+NGGKYCVG+R +++SCNT+ C + +R+ QC+ F
Sbjct: 598 GTCSRTCGGGIKTAIRECNRPEPKNGGKYCVGRRMKFKSCNTEPCLKQKRDFRDEQCAHF 657
Query: 2925 NNKDIGIQGVASTNTHWVPKYANVAPNERCKLYCRLSGSAAFYLLRDKVVDGTPCDRNGD 2746
+ K I G+ N WVPKY+ + +RCKL+CR++G+ A+Y LRD+V+DGTPC ++ +
Sbjct: 658 DGKHFNINGLLP-NVRWVPKYSGILMKDRCKLFCRVAGNTAYYQLRDRVIDGTPCGQDTN 716
Query: 2745 DICVAGACMPAGCDHQLHSTLRRDKCGVCGGDDSSCKVVKGTFNEQGTFGYNEVMKIPAG 2566
DICV G C AGCDH L+S RRDKCGVCGGD+SSCK V GTFN +GYN V++IPAG
Sbjct: 717 DICVQGLCRQAGCDHVLNSKARRDKCGVCGGDNSSCKTVAGTFNTV-HYGYNTVVRIPAG 775
Query: 2565 SANIDIRQKGYNNMKEDDNYLSLRAANGEFLLNGHFQVSLARQQIAFQDTVLEYSGSDAI 2386
+ NID+RQ ++ +DDNYL+L ++ GEFLLNG+F V++A+++I + V+EYSGS+
Sbjct: 776 ATNIDVRQHSFSGETDDDNYLALSSSKGEFLLNGNFVVTMAKREIRIGNAVVEYSGSETA 835
Query: 2385 IERINGTGPIRSDIYVHVLSVGS-HPPDISYEYMTAAVPNAVIRPISSALYLWRVTDTWT 2209
+ERIN T I ++ + VLSVG + PD+ Y + N I Y W W
Sbjct: 836 VERINSTDRIEQELLLQVLSVGKLYNPDVRYSF------NIPIEDKPQQFY-WNSHGPWQ 888
Query: 2208 ECDRACRGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRWITEDVSSCS 2029
C + C+G++ +KL+C S D+ C + +P T C DC RW S CS
Sbjct: 889 ACSKPCQGERKRKLVCTRESDQLTVSDQRCDRLPQPGHITEPCGTDCDLRWHVASRSECS 948
Query: 2028 AKCGSGQKRQRVSCVKME--GDRQTPASEHLCDRNSKPSDIASCYIDCSGRKWNYGEWTS 1855
A+CG G + + C K + + C + KPS+ C +C+ W Y WT
Sbjct: 949 AQCGLGYRTLDIYCAKYSRLDGKTEKVDDGFCSSHPKPSNREKCSGECNTGGWRYSAWTE 1008
Query: 1854 CSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWVYGHWSE 1684
CS++C G R++ CV+ N +D+S C ++K +R C+ PCP+W G WSE
Sbjct: 1009 CSKSC-DGGTQRRRAICVNTRNDVLDDSKCTHQEKVTIQR-CSEFPCPQWKSGDWSE 1063
Score = 89.7 bits (221), Expect = 6e-16
Identities = 53/196 (27%), Positives = 82/196 (41%), Gaps = 23/196 (11%)
Frame = -1
Query: 1878 WN-YGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCP--- 1711
WN +G W +CS+ C G+ RK C +S +Q +++ C+R+P P
Sbjct: 881 WNSHGPWQACSKPC--QGERKRKLVCTRES-----------DQLTVSDQRCDRLPQPGHI 927
Query: 1710 ----------RWVYGHWSECSRSCDGGVKMRHAQC-----LDAADRETHTSRCG----PA 1588
RW SECS C G + C LD + C P+
Sbjct: 928 TEPCGTDCDLRWHVASRSECSAQCGLGYRTLDIYCAKYSRLDGKTEKVDDGFCSSHPKPS 987
Query: 1587 QTQEHCNEHACTWWQFGVWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIITKP 1408
++ E W++ W++CS C G Q R A C + VL + +C EK+ +
Sbjct: 988 NREKCSGECNTGGWRYSAWTECSKSCDGGTQRRRAICVNTRNDVLDDSKCTHQEKVTIQR 1047
Query: 1407 CHRESCPKYKLGEWSQ 1360
C CP++K G+WS+
Sbjct: 1048 CSEFPCPQWKSGDWSE 1063
Score = 81.3 bits (199), Expect = 2e-13
Identities = 57/196 (29%), Positives = 79/196 (40%), Gaps = 11/196 (5%)
Frame = -1
Query: 1197 WSACSVSCGIGHRERTTECIYREQSVDASFCGDTKMPETSQTCHLL-PCTS-----WKPS 1036
W ACS C G R+R C + S D + Q H+ PC + W +
Sbjct: 887 WQACSKPCQ-GERKRKLVCTRESDQLTVS---DQRCDRLPQPGHITEPCGTDCDLRWHVA 942
Query: 1035 HWSPCSVTCGSGIQTRSVSCTRGS----EGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRV 868
S CS CG G +T + C + S + VD+ FC + +P ++ C + G
Sbjct: 943 SRSECSAQCGLGYRTLDIYCAKYSRLDGKTEKVDDGFCSSHPKPSNREKCSGECNTGG-- 1000
Query: 867 LQKLQADVPPIRWATGPWTACSATCGNGTQRRLLKCRDHVRD-LPDEYCNHLDKEVSTRN 691
W WT CS +C GTQRR C + D L D C H +K V+ +
Sbjct: 1001 ------------WRYSAWTECSKSCDGGTQRRRAICVNTRNDVLDDSKCTHQEK-VTIQR 1047
Query: 690 CRLRDCSYWKMAEWEE 643
C C WK +W E
Sbjct: 1048 CSEFPCPQWKSGDWSE 1063
Score = 77.4 bits (189), Expect = 3e-12
Identities = 53/186 (28%), Positives = 85/186 (45%), Gaps = 11/186 (5%)
Frame = -1
Query: 1551 WWQFGVWSDCSAKCGDGVQYRDANCT-DRHRSVLPEHRCLKMEKI--ITKPCHRESCPKY 1381
W G W CS C G + R CT + + + + RC ++ + IT+PC + ++
Sbjct: 881 WNSHGPWQACSKPC-QGERKRKLVCTRESDQLTVSDQRCDRLPQPGHITEPCGTDCDLRW 939
Query: 1380 KLGEWSQCSVSCEDGWSSRRVSC-----VSGNGTEVDMSLCGTASDRPASHQTCNLGTCP 1216
+ S+CS C G+ + + C + G +VD C ++ +P++ + C+ G C
Sbjct: 940 HVASRSECSAQCGLGYRTLDIYCAKYSRLDGKTEKVDDGFC-SSHPKPSNREKCS-GECN 997
Query: 1215 F--WRNTDWSACSVSCGIGHRERTTECI-YREQSVDASFCGDTKMPETSQTCHLLPCTSW 1045
WR + W+ CS SC G + R C+ R +D S C + T Q C PC W
Sbjct: 998 TGGWRYSAWTECSKSCDGGTQRRRAICVNTRNDVLDDSKCTHQE-KVTIQRCSEFPCPQW 1056
Query: 1044 KPSHWS 1027
K WS
Sbjct: 1057 KSGDWS 1062
Score = 77.0 bits (188), Expect = 4e-12
Identities = 56/188 (29%), Positives = 77/188 (40%), Gaps = 18/188 (9%)
Frame = -1
Query: 1701 YGHWSECSRSCDGGVKMRHAQCLDAADRETHTS-RCG----PAQTQEHCNEHACTWWQFG 1537
+G W CS+ C G K R C +D+ T + RC P E C W
Sbjct: 884 HGPWQACSKPCQGERK-RKLVCTRESDQLTVSDQRCDRLPQPGHITEPCGTDCDLRWHVA 942
Query: 1536 VWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIIT-------KPCHRESCPK-- 1384
S+CSA+CG G + D C R K EK+ KP +RE C
Sbjct: 943 SRSECSAQCGLGYRTLDIYCAKYSRLDG------KTEKVDDGFCSSHPKPSNREKCSGEC 996
Query: 1383 ----YKLGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTCP 1216
++ W++CS SC+ G RR CV+ +D S C + Q C+ CP
Sbjct: 997 NTGGWRYSAWTECSKSCDGGTQRRRAICVNTRNDVLDDSKC--THQEKVTIQRCSEFPCP 1054
Query: 1215 FWRNTDWS 1192
W++ DWS
Sbjct: 1055 QWKSGDWS 1062
Score = 70.1 bits (170), Expect = 5e-10
Identities = 53/196 (27%), Positives = 80/196 (40%), Gaps = 15/196 (7%)
Frame = -1
Query: 822 GPWTACSATCGNGTQRRLLKCRDHVR-DLPDEYCNHLDK-----EVSTRNCRLRDCSYWK 661
GPW ACS C +R+L+ R+ + + D+ C+ L + E +C LR W
Sbjct: 885 GPWQACSKPCQGERKRKLVCTRESDQLTVSDQRCDRLPQPGHITEPCGTDCDLR----WH 940
Query: 660 MAEWEECPATCGTHVQQSRNVTCV--SAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPK 487
+A EC A CG ++ ++ C S DG + D C +P++ C
Sbjct: 941 VASRSECSAQCGLG-YRTLDIYCAKYSRLDGKTEKVDDGFCSSHPKPSNREKC------S 993
Query: 486 GEEHIGSWIIGDWSKCSASCGGGWXXXXXXXXXXXCDE------TRKPKM-FDKCNEELC 328
GE + G W W++CS SC GG D T + K+ +C+E C
Sbjct: 994 GECNTGGWRYSAWTECSKSCDGGTQRRRAICVNTRNDVLDDSKCTHQEKVTIQRCSEFPC 1053
Query: 327 PPLTNNSWQISPWTHC 280
P + W W C
Sbjct: 1054 PQWKSGDWSEVRWEGC 1069
Score = 63.9 bits (154), Expect = 4e-08
Identities = 53/189 (28%), Positives = 73/189 (38%), Gaps = 14/189 (7%)
Frame = -1
Query: 669 YWKM-AEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPC 493
YW W+ C C ++ R + C D + + D CD +P EPC
Sbjct: 880 YWNSHGPWQACSKPC--QGERKRKLVCTRESD--QLTVSDQRCDRLPQPGHIT----EPC 931
Query: 492 PKGEEHIGSWIIGDWSKCSASCGGGWXXXXXXXXXXXCDETRKPKMFD--------KCNE 337
G + W + S+CSA CG G+ + + K+ D N
Sbjct: 932 --GTDCDLRWHVASRSECSAQCGLGYRTLDIYCAKYSRLDGKTEKVDDGFCSSHPKPSNR 989
Query: 336 ELCPPLTNNS-WQISPWTHCSVSCGGGVQRRKIWC----EDVLSGRKQDDIECSEIKPRE 172
E C N W+ S WT CS SC GG QRR+ C DVL DD +C+ +
Sbjct: 990 EKCSGECNTGGWRYSAWTECSKSCDGGTQRRRAICVNTRNDVL-----DDSKCTHQEKVT 1044
Query: 171 QRDCEMPPC 145
+ C PC
Sbjct: 1045 IQRCSEFPC 1053
>gi|48103363|ref|XP_395557.1| similar to a disintegrin and
metalloproteinase with thrombospondin motifs 9 isoform 1
preproprotein [Apis mellifera]
Length = 1195
Score = 721 bits (1862), Expect = 0.0
Identities = 413/1113 (37%), Positives = 593/1113 (53%), Gaps = 72/1113 (6%)
Frame = -1
Query: 4134 RSRRAANSWDHYVEVLVVADTKMYEYHGRSLEDYVLTLFSTVASIYRHQSLRASXXXXXX 3955
R RRA +S ++++E++V AD +M YHG+ L Y+L L STV+ IY+ S+ +
Sbjct: 128 RPRRALSS-EYFIEIMVAADAEMVRYHGKGLLGYILGLMSTVSRIYKDPSI-GNPISISV 185
Query: 3954 XXXXXKTENAGPRITQN----AQQTLQDFCRWQQYYNDPDDSSVQHHDVAILLTRKDICR 3787
+ G R T+ A L FCRWQQ N+P++ S H+D A+LLTR+++C
Sbjct: 186 MSIVPIDKIFGVRRTKGEGIAAADMLNKFCRWQQS-NNPNEYSPGHYDTALLLTRENLCH 244
Query: 3786 S--QGKCDTLGLAELGTMCDMQKSCAIIEDNGLSAAFTIAHELGHVFSIPHDDERKCSTY 3613
+ Q CDTLGLAELG MC + SCAI++DNGL+AAFTIAHE+GHV +PHDD+ KC+ Y
Sbjct: 245 NSDQRNCDTLGLAELGRMCSPRSSCAIVQDNGLAAAFTIAHEIGHVLDMPHDDDVKCAAY 304
Query: 3612 MPVNKVCKFQSTKFDKTQFQNNFHIMAPTLEYNTHPWSWSPCSAGMLERFLENNRGQTQC 3433
+++ N IM+ L+ NT PW WS CS + FLE +G C
Sbjct: 305 K-------------NRSGMHN---IMSRMLDDNTFPWEWSKCSRHYVTEFLEAGKGD--C 346
Query: 3432 LFDQPVERRYYEDVFVRDEPGKKYDAHQQCKFVFGPASELCPYM------PTCRRLWCAT 3271
L D P + E R PG+ Y ++QC+ VFG S +C +M CRRLWC T
Sbjct: 347 LLDTP--DKIMERTDPRRLPGEDYSVNKQCELVFGNGSRICNHMVGDGKSAVCRRLWCTT 404
Query: 3270 FYGSQMG-CRTQHMPWADGTPCDESRSMFCHHGACVRLAPESLTKIDGQWGDWRSWGECS 3094
CRTQHMPWADGT C R +C+ G CV + +L +DGQWG+W +G+CS
Sbjct: 405 PNEDHYDHCRTQHMPWADGTSC--GRDKWCYRGECVSRSL-NLQPVDGQWGEWGRYGKCS 461
Query: 3093 RTCGGGVQKGLRDCDSPKPRNGGKYCVGQRERYRSCNTQECPWDTQPYREVQCSEFNNKD 2914
RTCGGGV+K R+CD+P P+NGG+YC+G++ +YRSC T+ECP T +R+ QCS FNN +
Sbjct: 462 RTCGGGVKKKYRECDNPLPQNGGRYCIGEQVKYRSCGTRECPPGTPDFRDQQCSYFNNNN 521
Query: 2913 IGIQGVASTNTHWVPKYANVAPNERCKLYCRLSGSAAFYLLRDKVVDGTPCDRNGDDICV 2734
+ I+ + S + W +A + P+ERCKLYC + S Y L +KV+DGTPCD++ ICV
Sbjct: 522 LNIKNL-SRDVKW---HAKILPHERCKLYCE-TDSNQCYPLAEKVIDGTPCDQDTFHICV 576
Query: 2733 AGACMPAGCDHQLHSTLRRDKCGVCGGDDSSCKVVKGTFNEQGTFGYNEVMKIPAGSANI 2554
G C PAGCDH L+ST D CGVC GD+S+C+ + G++N +GY + KIPAGS NI
Sbjct: 577 NGFCKPAGCDHVLNSTAELDICGVCKGDNSTCQWITGSYNST-QYGYTRIAKIPAGSNNI 635
Query: 2553 DIRQKGYNNMKEDDNYLSLR-AANGEFLLNGHFQVSLARQQIAFQDTVLEYSGSDAIIER 2377
DIRQ G+ +M +D NYL+LR G++++NG+F+V + ++ I +EYSG D+ +ER
Sbjct: 636 DIRQPGWKDMIDDGNYLALRLGEGGKYIVNGNFKV-MTQRVIVDIGVTIEYSGRDSRVER 694
Query: 2376 INGTGPIRSDIYVHVLSVGS-HPPDISYEYMTAAVPNAVIRPISSALYLWRVTDTWTECD 2200
+N + PI +D+ + VLSV +PP ISY+Y VP ++ Y W+++ W++C
Sbjct: 695 LNTSRPIETDLILEVLSVSELNPPQISYKY---TVPRKILES-----YEWKLSG-WSDCT 745
Query: 2199 RACRGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRWITEDVSSCSAKC 2020
R C+G + +K C ++ D C+ KP++ ++MCN C W VS CS C
Sbjct: 746 RTCQGIKYRKAECTNIEYKEVVADDYCRESEKPREESQMCNNHCVLEW-NITVSECSNHC 804
Query: 2019 GSGQKRQRVSCV-KMEGDRQTPAS--EHLCDRNSKPSDIASCYIDCSGRKWNYGEWTSCS 1849
G G + C+ K+ P + H C +P++ SC C W+YG+W++C+
Sbjct: 805 GLGTRVVTSRCIQKLLNSNHPPRAIPPHSCAHLERPNETESCMGPCEDAHWSYGKWSACN 864
Query: 1848 ETCGSNGKMHRKSYCVDDSNRRVDESLCGREQKEATERECNRIPCPRWVYGHWSECSRSC 1669
TCG G +R + C+D + R V E C Q++ E C PCP+W + +WS CS +C
Sbjct: 865 ATCG-GGIQYRTATCIDSNQRTVSEENC-MGQRKVLENACANDPCPKWTFKNWSNCSVTC 922
Query: 1668 DGGVKMRHAQCLDAADRETHTSRCG--PAQTQEHCNEHACTWWQFGVWSDCSAKCGDGVQ 1495
G + C +R + CG P + + CN C W G WS CS CG+G++
Sbjct: 923 GIGKQYSRYAC-HIENRVVPDNYCGKPPLEITQACNSGPCEQWHKGDWSACSVTCGEGIK 981
Query: 1494 YRDANCTDRHRSVLPEHRCLKMEK--------------IITKPCHRESCPKYKL------ 1375
R C + + ++C K + P S P Y++
Sbjct: 982 RRKVIC--KTLDGITSNKCSASNKPDNITACILKSCPTVNVTPIKYSSDPPYEIPSQQDN 1039
Query: 1374 --------------GEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQT 1237
E +CS C G+ + V CVS V +P++
Sbjct: 1040 EVHDIIFHYGYKWHTETQKCSKPCIKGYMNTTVKCVSIETGIVAPDRYCDNEKKPSTEIP 1099
Query: 1236 CNLGTCPFWRNTDWS---------ACSVSCGIGHRERTTECIYR------EQSVDASFCG 1102
CN CP W +DW CS SCG G + R EC R E +V C
Sbjct: 1100 CNRFHCPIWITSDWGQFGSNENVLQCSKSCGTGLQRRRVECTMRRGNHGPEVTVRDEHCS 1159
Query: 1101 --DTKMPETSQTCHLLPCT-SWKPSHWSPCSVT 1012
+ P + + C + C W+ WS VT
Sbjct: 1160 RLGLRKPRSQRPCRRIACNYIWQEGPWSEKIVT 1192
Score = 173 bits (438), Expect = 4e-41
Identities = 127/472 (26%), Positives = 186/472 (38%), Gaps = 50/472 (10%)
Frame = -1
Query: 1707 WVYGHWSECSRSCDGGVKMRHAQCLDAADRETHTSRC-----GPAQTQEHCNEHACTWWQ 1543
W WS+C+R+C G +K R A+C + +E P + + CN H W
Sbjct: 736 WKLSGWSDCTRTCQG-IKYRKAECTNIEYKEVVADDYCRESEKPREESQMCNNHCVLEWN 794
Query: 1542 FGVWSDCSAKCGDGVQYRDANCTDRHRS------VLPEHRCLKMEKIITKPCHRESC--- 1390
V S+CS CG G + + C + + +P H C +E+ P ESC
Sbjct: 795 ITV-SECSNHCGLGTRVVTSRCIQKLLNSNHPPRAIPPHSCAHLER----PNETESCMGP 849
Query: 1389 ---PKYKLGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASHQTCNLGTC 1219
+ G+WS C+ +C G R +C+ N V C R C C
Sbjct: 850 CEDAHWSYGKWSACNATCGGGIQYRTATCIDSNQRTVSEENC--MGQRKVLENACANDPC 907
Query: 1218 PFWRNTDWSACSVSCGIGHRERTTECIYREQSVDASFCGDTKMPETSQTCHLLPCTSWKP 1039
P W +WS CSV+CGIG + C + V ++CG + E +Q C+ PC W
Sbjct: 908 PKWTFKNWSNCSVTCGIGKQYSRYACHIENRVVPDNYCGKPPL-EITQACNSGPCEQWHK 966
Query: 1038 SHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQK 859
WS CSVTCG GI+ R V C + +G ++ C + +P C +C V
Sbjct: 967 GDWSACSVTCGEGIKRRKVIC-KTLDGITSNK--CSASNKPDNITACILKSCPTVNVTPI 1023
Query: 858 LQADVPP-------------------IRWATGPWTACSATCGNGTQRRLLKCRDHVRDL- 739
+ PP +W T CS C G +KC +
Sbjct: 1024 KYSSDPPYEIPSQQDNEVHDIIFHYGYKWHT-ETQKCSKPCIKGYMNTTVKCVSIETGIV 1082
Query: 738 -PDEYCNHLDKEVSTRNCRLRDCSYWKMAEWE---------ECPATCGTHVQQSR-NVTC 592
PD YC++ K + C C W ++W +C +CGT +Q+ R T
Sbjct: 1083 APDRYCDNEKKPSTEIPCNRFHCPIWITSDWGQFGSNENVLQCSKSCGTGLQRRRVECTM 1142
Query: 591 VSAEDGGRTILKDVDCD--VQKRPTSARNCRLEPCPKGEEHIGSWIIGDWSK 442
G ++D C ++P S R CR C +I W G WS+
Sbjct: 1143 RRGNHGPEVTVRDEHCSRLGLRKPRSQRPCRRIAC----NYI--WQEGPWSE 1188
Score = 153 bits (387), Expect = 4e-35
Identities = 126/471 (26%), Positives = 178/471 (37%), Gaps = 57/471 (12%)
Frame = -1
Query: 1386 KYKLGEWSQCSVSCEDGWSSRRVSCVSGNGTEVDMSLCGTASDRPASH-QTCNLGTCPFW 1210
++KL WS C+ +C+ G R+ C + EV S++P Q CN C
Sbjct: 735 EWKLSGWSDCTRTCQ-GIKYRKAECTNIEYKEVVADDYCRESEKPREESQMCN-NHCVLE 792
Query: 1209 RNTDWSACSVSCGIGHRERTTECIYR-------EQSVDASFCGDTKMPETSQTCHLLPCT 1051
N S CS CG+G R T+ CI + +++ C + P +++C + PC
Sbjct: 793 WNITVSECSNHCGLGTRVVTSRCIQKLLNSNHPPRAIPPHSCAHLERPNETESC-MGPCE 851
Query: 1050 S--WKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDG 877
W WS C+ TCG GIQ R+ +C ++ T+ +E C G
Sbjct: 852 DAHWSYGKWSACNATCGGGIQYRTATCIDSNQRTVSEE------------------NCMG 893
Query: 876 PR-VLQKLQADVPPIRWATGPWTACSATCGNGTQRRLLKCRDHVRDLPDEYCNHLDKEVS 700
R VL+ A+ P +W W+ CS TCG G Q C R +PD YC E+
Sbjct: 894 QRKVLENACANDPCPKWTFKNWSNCSVTCGIGKQYSRYACHIENRVVPDNYCGKPPLEI- 952
Query: 699 TRNCRLRDCSYWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTS 520
T+ C C W +W C TCG +++ R V C + + G T K C +P +
Sbjct: 953 TQACNSGPCEQWHKGDWSACSVTCGEGIKR-RKVICKTLD--GITSNK---CSASNKPDN 1006
Query: 519 ARNCRLEPCPKGEE--------------------------HIGSWIIGDWSKCSASCGGG 418
C L+ CP H G + KCS C G
Sbjct: 1007 ITACILKSCPTVNVTPIKYSSDPPYEIPSQQDNEVHDIIFHYGYKWHTETQKCSKPCIKG 1066
Query: 417 WXXXXXXXXXXXC---------DETRKPKMFDKCNEELCPPLTNNSW----QISPWTHCS 277
+ D +KP CN CP + W CS
Sbjct: 1067 YMNTTVKCVSIETGIVAPDRYCDNEKKPSTEIPCNRFHCPIWITSDWGQFGSNENVLQCS 1126
Query: 276 VSCGGGVQRRKIWCEDVLSGRKQD----DIECSEI---KPREQRDCEMPPC 145
SCG G+QRR++ C + D CS + KPR QR C C
Sbjct: 1127 KSCGTGLQRRRVECTMRRGNHGPEVTVRDEHCSRLGLRKPRSQRPCRRIAC 1177
Score = 115 bits (289), Expect = 8e-24
Identities = 90/322 (27%), Positives = 134/322 (40%), Gaps = 15/322 (4%)
Frame = -1
Query: 1065 LLPCTSWKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDT 886
+L WK S WS C+ TC GI+ R CT +V + +C + +PR E
Sbjct: 730 ILESYEWKLSGWSDCTRTC-QGIKYRKAECTNIEYKEVVADDYCRESEKPRE----ESQM 784
Query: 885 CDGPRVLQKLQADVPPIRWATGPWTACSATCGNGTQ-------RRLLKCRDHVRDLPDEY 727
C+ VL+ W + CS CG GT+ ++LL R +P
Sbjct: 785 CNNHCVLE----------WNITV-SECSNHCGLGTRVVTSRCIQKLLNSNHPPRAIPPHS 833
Query: 726 CNHLDKEVSTRNCRLRDC--SYWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKD 553
C HL++ T +C + C ++W +W C ATCG +Q R TC+ D + + +
Sbjct: 834 CAHLERPNETESC-MGPCEDAHWSYGKWSACNATCGGGIQY-RTATCI---DSNQRTVSE 888
Query: 552 VDCDVQKRPTSARNCRLEPCPKGEEHIGSWIIGDWSKCSASCGGGWXXXXXXXXXXXC-- 379
+C + +R C +PCPK W +WS CS +CG G
Sbjct: 889 ENC-MGQRKVLENACANDPCPK-------WTFKNWSNCSVTCGIGKQYSRYACHIENRVV 940
Query: 378 --DETRKP--KMFDKCNEELCPPLTNNSWQISPWTHCSVSCGGGVQRRKIWCEDVLSGRK 211
+ KP ++ CN C W W+ CSV+CG G++RRK+ C+ L G
Sbjct: 941 PDNYCGKPPLEITQACNSGPC-----EQWHKGDWSACSVTCGEGIKRRKVICK-TLDGIT 994
Query: 210 QDDIECSEIKPREQRDCEMPPC 145
+ S KP C + C
Sbjct: 995 SNKCSASN-KPDNITACILKSC 1015
Score = 37.4 bits (85), Expect(2) = 0.89
Identities = 32/137 (23%), Positives = 54/137 (39%), Gaps = 1/137 (0%)
Frame = -1
Query: 1080 SQTCHLLPCTSWKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKT 901
S C L CT+ H+ C +T+ + G+ C R+ K
Sbjct: 394 SAVCRRLWCTTPNEDHYDHC--------RTQHMPWADGTS--------CGRD------KW 431
Query: 900 CEKDTCDGPRVLQKLQADVPPIRWAT-GPWTACSATCGNGTQRRLLKCRDHVRDLPDEYC 724
C + C V + L +W G + CS TCG G +++ +C + + YC
Sbjct: 432 CYRGEC----VSRSLNLQPVDGQWGEWGRYGKCSRTCGGGVKKKYRECDNPLPQNGGRYC 487
Query: 723 NHLDKEVSTRNCRLRDC 673
+ ++V R+C R+C
Sbjct: 488 --IGEQVKYRSCGTREC 502
Score = 20.8 bits (42), Expect(2) = 0.89
Identities = 8/17 (47%), Positives = 11/17 (64%)
Frame = -3
Query: 559 ERC*L*CAKETNKCKKL 509
ERC L C ++N+C L
Sbjct: 541 ERCKLYCETDSNQCYPL 557