Homology by BLASTX
BLASTX 2.2.4 [Aug-26-2002]
Query= T21E3_3
(6579 letters)
Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
1,967,186 sequences; 661,712,633 total letters
Score E
Sequences producing significant alignments: (bits) Value
gi|17509113|ref|NP_491270.1| lipoprotein receptor-related protei... 4685 0.0
gi|7508146|pir||T29764 hypothetical protein T21E3.3 - Caenorhabd... 4512 0.0
gi|39586294|emb|CAE66705.1| Hypothetical protein CBG12050 [Caeno... 3833 0.0
gi|31239543|ref|XP_320185.1| ENSANGP00000011153 [Anopheles gambi... 890 0.0
gi|28573304|ref|NP_788284.1| CG33087-PC [Drosophila melanogaster... 863 0.0
gi|45382557|ref|NP_990573.1| low density lipoprotein-related pro... 862 0.0
gi|15825005|gb|AAL09566.1| lipoprotein receptor-related protein ... 860 0.0
gi|15825096|gb|AAL09567.1| lipoprotein receptor-related protein ... 860 0.0
gi|34865759|ref|XP_243524.2| similar to lipoprotein receptor-rel... 848 0.0
gi|6678720|ref|NP_032538.1| low density lipoprotein receptor-rel... 845 0.0
gi|4758686|ref|NP_002323.1| low density lipoprotein-related prot... 830 0.0
gi|16519539|ref|NP_443737.1| low density lipoprotein-related pro... 790 0.0
gi|47229537|emb|CAG06733.1| unnamed protein product [Tetraodon n... 785 0.0
gi|9055270|ref|NP_061027.1| low density lipoprotein-related prot... 773 0.0
gi|47228669|emb|CAG07401.1| unnamed protein product [Tetraodon n... 771 0.0
gi|13562118|ref|NP_110454.1| low density lipoprotein receptor-re... 743 0.0
gi|34854634|ref|XP_346657.1| hypothetical protein XP_346656 [Rat... 741 0.0
gi|38074796|ref|XP_130308.2| similar to low density lipoprotein ... 730 0.0
gi|6806919|ref|NP_004516.1| low density lipoprotein-related prot... 728 0.0
gi|32816597|gb|AAP88586.1| glycoprotein receptor gp330/megalin p... 727 0.0
gi|32816595|gb|AAP88585.1| glycoprotein receptor gp330/megalin p... 726 0.0
gi|50750481|ref|XP_422014.1| PREDICTED: similar to glycoprotein ... 717 0.0
gi|1389559|gb|AAB02882.1| glycoprotein 330 704 0.0
gi|50750792|ref|XP_422146.1| PREDICTED: similar to Low-density l... 701 0.0
gi|34853954|ref|XP_231214.2| similar to low density lipoprotein ... 696 0.0
gi|47210425|emb|CAF92450.1| unnamed protein product [Tetraodon n... 677 0.0
gi|24640820|ref|NP_572563.2| CG12139-PB [Drosophila melanogaster... 659 0.0
gi|16768036|gb|AAL28237.1| GH12891p [Drosophila melanogaster] 659 0.0
gi|31203671|ref|XP_310784.1| ENSANGP00000014849 [Anopheles gambi... 655 0.0
gi|48137733|ref|XP_393369.1| similar to ENSANGP00000014849 [Apis... 620 e-175
gi|47219712|emb|CAG12634.1| unnamed protein product [Tetraodon n... 619 e-175
gi|3170549|gb|AAC34396.1| LRP1 [Takifugu rubripes] 591 e-167
gi|39582476|emb|CAE66567.1| Hypothetical protein CBG11882 [Caeno... 572 e-161
gi|17298317|gb|AAL38109.1| candidate tumor suppressor protein [H... 570 e-160
gi|17508271|ref|NP_492127.1| EGF motif related, Low-density lipo... 569 e-160
gi|1083645|pir||S53457 dominant autoantigen gp 330 - rat (fragme... 559 e-157
gi|28572059|ref|NP_733118.2| CG31092-PA [Drosophila melanogaster... 434 e-119
gi|47117264|sp|Q8VI56|LRP4_MOUSE Low-density lipoprotein recepto... 432 e-119
gi|47116978|sp|Q9QYP1|LRP4_RAT Low-density lipoprotein receptor-... 431 e-118
gi|47117042|sp|O75096|LRP4_HUMAN Low-density lipoprotein recepto... 427 e-117
gi|27883856|ref|NP_766256.2| low density lipoprotein receptor-re... 427 e-117
gi|47271362|ref|NP_112612.1| low density lipoprotein receptor-re... 425 e-117
gi|50748119|ref|XP_421114.1| PREDICTED: similar to Low-density l... 422 e-116
gi|2764400|emb|CAA03855.1| lipophorin receptor [Locusta migratoria] 403 e-110
gi|34856544|ref|XP_342465.1| low density lipoprotein receptor-re... 402 e-110
gi|45553532|ref|NP_996296.1| CG31094-PB [Drosophila melanogaster... 401 e-109
gi|39840998|gb|AAR31134.1| LD21010p [Drosophila melanogaster] 401 e-109
gi|33589552|gb|AAQ22543.1| LD11117p [Drosophila melanogaster] 399 e-109
gi|45382563|ref|NP_990560.1| very low density lipoprotein (VLDL)... 397 e-108
gi|31204353|ref|XP_311125.1| ENSANGP00000017336 [Anopheles gambi... 394 e-107
gi|1730112|sp|P98156|LDVR_MOUSE Very low-density lipoprotein rec... 394 e-107
gi|6981706|ref|NP_037287.1| very low density lipoprotein recepto... 392 e-107
gi|7305629|ref|NP_038731.1| very low density lipoprotein recepto... 391 e-106
gi|15489005|gb|AAH13622.1| Vldlr protein [Mus musculus] 391 e-106
gi|609533|gb|AAC37668.1| very low density lipoprotein receptor 390 e-106
gi|40231967|gb|AAR83314.1| very low density lipoprotein receptor... 390 e-106
gi|1730111|sp|P98155|LDVR_HUMAN Very low-density lipoprotein rec... 388 e-105
gi|437387|gb|AAA61344.1| very low density lipoprotein receptor 388 e-105
gi|14718545|gb|AAK72954.1| lipophorin receptor [Aedes aegypti] 388 e-105
gi|40254473|ref|NP_003374.2| very low density lipoprotein recept... 387 e-105
gi|391736|dbj|BAA03946.1| very low density lipoprotein receptor ... 387 e-105
gi|47117276|sp|Q924X6|LRP8_MOUSE Low-density lipoprotein recepto... 383 e-104
gi|16716347|ref|NP_444303.1| low density lipoprotein receptor-re... 383 e-104
gi|45383976|ref|NP_990517.1| LR8B protein [Gallus gallus] >gnl|B... 383 e-104
gi|16610195|emb|CAD10640.1| vitellogenin receptor [Oncorhynchus ... 382 e-104
gi|7438663|pir||JE0237 apolipoprotein E receptor 2 precursor - m... 380 e-103
gi|27806193|ref|NP_776914.1| very low density lipoprotein recept... 378 e-103
gi|547843|sp|P35953|LDVR_RABIT Very low-density lipoprotein rece... 377 e-102
gi|31198095|ref|XP_307995.1| ENSANGP00000006309 [Anopheles gambi... 377 e-102
gi|33589593|gb|AAQ22563.1| GH26833p [Drosophila melanogaster] 375 e-102
gi|28572061|ref|NP_788742.1| CG31092-PB [Drosophila melanogaster... 375 e-102
gi|37728099|gb|AAO92396.1| vitellogenin receptor [Morone americana] 374 e-101
gi|37541633|ref|XP_035037.3| low density lipoprotein receptor-re... 373 e-101
gi|27923331|gb|AAO27569.1| vitellogenin receptor [Oreochromis au... 372 e-101
gi|24650134|ref|NP_733119.1| CG31094-PA [Drosophila melanogaster... 370 e-100
gi|126074|sp|P20063|LDLR_RABIT Low-density lipoprotein receptor ... 370 e-100
gi|33356181|gb|AAQ16410.1| lipophorin receptor [Aedes aegypti] 370 e-100
gi|47228667|emb|CAG07399.1| unnamed protein product [Tetraodon n... 366 4e-99
gi|6754526|ref|NP_034830.1| low density lipoprotein receptor [Mu... 366 5e-99
gi|16506799|gb|AAL23955.1| low density lipoprotein receptor [Mus... 366 5e-99
gi|17512511|gb|AAH19207.1| Ldlr protein [Mus musculus] 365 6e-99
gi|7428600|pir||QRMSLD LDL receptor precursor - mouse >gnl|BL_OR... 365 6e-99
gi|49823250|gb|AAT68691.1| megalin [Didelphis virginiana] 365 6e-99
gi|2118675|pir||JC4858 VLDL receptor precursor - African clawed ... 364 1e-98
gi|476531|pir||QRXLL1 LDL receptor 1 precursor - African clawed ... 363 2e-98
gi|39840984|gb|AAR31128.1| RE40649p [Drosophila melanogaster] 363 2e-98
gi|3201962|gb|AAC39254.1| low density lipoprotein receptor [Sus ... 363 2e-98
gi|3153895|gb|AAC17444.1| low density lipoprotein receptor [Sus ... 363 2e-98
gi|47123899|gb|AAH70552.1| VLDLR protein [Xenopus laevis] 363 2e-98
gi|547838|sp|Q99087|LDL1_XENLA Low-density lipoprotein receptor ... 363 3e-98
gi|547839|sp|Q99088|LDL2_XENLA Low-density lipoprotein receptor ... 362 5e-98
gi|547840|sp|P35950|LDLR_CRIGR Low-density lipoprotein receptor ... 360 2e-97
gi|476532|pir||QRXLL2 LDL receptor 2 precursor - African clawed ... 359 6e-97
gi|4504975|ref|NP_000518.1| low density lipoprotein receptor pre... 357 2e-96
gi|32880123|gb|AAP88892.1| low density lipoprotein receptor (fam... 357 2e-96
gi|28373937|pdb|1N7D|A Chain A, Extracellular Domain Of The Ldl ... 357 2e-96
gi|16549252|dbj|BAB70786.1| unnamed protein product [Homo sapiens] 356 5e-96
gi|6691161|gb|AAF24515.1| low density lipoprotein receptor [Homo... 355 1e-95
gi|40231914|gb|AAR83313.1| low density lipoprotein receptor [Mac... 353 2e-95
gi|24642347|ref|NP_727914.1| CG8909-PB [Drosophila melanogaster]... 353 4e-95
gi|476530|pir||QRRTLD LDL receptor precursor - rat 352 7e-95
gi|28461161|ref|NP_786938.1| Low density lipoprotein receptor; L... 351 1e-94
gi|39590231|emb|CAE65969.1| Hypothetical protein CBG11153 [Caeno... 351 2e-94
gi|46195864|gb|AAS80339.1| Hypothetical protein T13C2.6b [Caenor... 350 3e-94
gi|4235639|gb|AAD13300.1| low density lipoprotein receptor [Sus ... 350 3e-94
gi|46195863|gb|AAS80338.1| Hypothetical protein T13C2.6a [Caenor... 350 3e-94
gi|30354634|gb|AAH51836.1| LRP8 protein [Homo sapiens] 348 8e-94
gi|47213812|emb|CAF92585.1| unnamed protein product [Tetraodon n... 348 8e-94
gi|4758688|ref|NP_004622.1| low density lipoprotein receptor-rel... 346 4e-93
gi|47227965|emb|CAF97594.1| unnamed protein product [Tetraodon n... 345 7e-93
gi|47229539|emb|CAG06735.1| unnamed protein product [Tetraodon n... 344 1e-92
gi|25012574|gb|AAN71387.1| RE38584p [Drosophila melanogaster] 340 4e-91
gi|8928354|sp|Q98930|SORL_CHICK Sortilin-related receptor (Sorti... 339 5e-91
gi|17298316|gb|AAL38108.1| candidate tumor suppressor protein [H... 334 2e-89
gi|2654025|gb|AAC16739.1| gp250 precursor [Mus musculus] 330 2e-88
gi|4507157|ref|NP_003096.1| sortilin-related receptor containing... 330 2e-88
gi|8928391|sp|O88307|SORL_MOUSE Sortilin-related receptor precur... 329 6e-88
gi|1817731|gb|AAB42184.1| low-density lipoprotein receptor [Chil... 328 8e-88
gi|8928392|sp|Q95209|SORL_RABIT Sortilin-related receptor precur... 328 1e-87
gi|45597451|ref|NP_035566.1| sortilin-related receptor, LDLR cla... 327 2e-87
gi|38074798|ref|XP_130363.2| low density lipoprotein receptor-re... 317 2e-84
gi|38089794|ref|XP_287900.2| similar to Sortilin-related recepto... 317 2e-84
gi|31198105|ref|XP_308000.1| ENSANGP00000013335 [Anopheles gambi... 315 7e-84
gi|17507419|ref|NP_491271.1| lipoprotein receptor-related protei... 315 9e-84
gi|47230767|emb|CAF99960.1| unnamed protein product [Tetraodon n... 314 2e-83
gi|34878705|ref|XP_237984.2| similar to low density lipoprotein ... 311 1e-82
gi|38089188|ref|XP_146277.4| similar to low density lipoprotein ... 311 1e-82
gi|14018364|emb|CAC38356.1| ApoE receptor-2 [Mus musculus] 310 4e-82
gi|31201695|ref|XP_309795.1| ENSANGP00000012534 [Anopheles gambi... 306 4e-81
gi|30385210|gb|AAP22970.1| low density lipoprotein receptor [Dan... 305 1e-80
gi|47217043|emb|CAG10095.1| unnamed protein product [Tetraodon n... 305 1e-80
gi|45383257|ref|NP_989783.1| LDL receptor [Gallus gallus] >gnl|B... 304 2e-80
gi|21750962|dbj|BAC03874.1| unnamed protein product [Homo sapiens] 300 2e-79
gi|48096771|ref|XP_392519.1| similar to ENSANGP00000012534 [Apis... 300 3e-79
gi|34853956|ref|XP_231215.2| similar to low density lipoprotein ... 299 7e-79
gi|47206272|emb|CAF92386.1| unnamed protein product [Tetraodon n... 298 9e-79
gi|32565014|ref|NP_872023.1| low density lipoprotein-receptor, c... 294 2e-77
gi|17536249|ref|NP_495387.1| low density lipoprotein-receptor, c... 293 3e-77
gi|7507774|pir||T16860 hypothetical protein T13C2.4 - Caenorhabd... 293 3e-77
gi|41016740|dbj|BAC02725.2| vitellogenin receptor [Periplaneta a... 292 9e-77
gi|5457146|gb|AAD43811.1| head-activator binding protein precurs... 279 6e-73
gi|50766215|ref|XP_426898.1| PREDICTED: similar to alpha-2-macro... 277 2e-72
gi|7494499|pir||T31330 head-activator binding protein precursor ... 276 4e-72
gi|26328189|dbj|BAC27835.1| unnamed protein product [Mus musculus] 276 5e-72
gi|31203447|ref|XP_310672.1| ENSANGP00000020798 [Anopheles gambi... 276 5e-72
gi|7511796|pir||T18308 probable vitellogenin receptor - yellow f... 274 2e-71
gi|24763|emb|CAA38905.1| alpha-2 macroglobulin receptor [Homo sa... 273 3e-71
gi|92331|pir||A30363 glycoprotein GP330, renal - rat (fragments) 271 1e-70
gi|47214294|emb|CAG00960.1| unnamed protein product [Tetraodon n... 267 2e-69
gi|28316919|gb|AAO39481.1| RE59172p [Drosophila melanogaster] 266 5e-69
gi|24641935|ref|NP_511151.2| CG1372-PA [Drosophila melanogaster]... 265 9e-69
gi|15451866|ref|NP_059992.2| low density lipoprotein receptor-re... 265 9e-69
gi|7512012|pir||T13171 probable vitellogenin receptor - fruit fl... 265 9e-69
gi|45555120|ref|NP_996433.1| CG1372-PB [Drosophila melanogaster]... 265 9e-69
gi|34870155|ref|XP_342878.1| similar to ApoE receptor-2 [Rattus ... 261 2e-67
gi|18957994|gb|AAL79675.1| putative ovarian lipoprotein receptor... 259 6e-67
gi|1834534|emb|CAA99509.1| apolipoprotein E receptor 2 906 [Homo... 256 7e-66
gi|42521628|gb|AAP92450.1| vitellogenin receptor [Solenopsis inv... 254 2e-65
gi|47216973|emb|CAG04915.1| unnamed protein product [Tetraodon n... 244 2e-62
gi|15451868|ref|NP_150643.1| low density lipoprotein receptor-re... 241 1e-61
gi|46561850|gb|AAT01142.1| proteoliaisin [Lytechinus variegatus] 241 1e-61
gi|39595186|emb|CAE60223.1| Hypothetical protein CBG03794 [Caeno... 238 1e-60
gi|7511475|pir||T37475 lipoprotein receptor precursor - Caenorha... 237 3e-60
gi|4097463|gb|AAD09363.1| lipoprotein receptor precursor [Caenor... 237 3e-60
gi|25152990|ref|NP_500815.2| yolk receptor, LDL receptor superfa... 236 6e-60
gi|5919205|gb|AAD56241.1| yolk receptor RME-2 [Caenorhabditis el... 232 1e-58
gi|3449306|dbj|BAA32468.1| MEGF7 [Homo sapiens] 230 3e-58
gi|3021534|emb|CAA05873.1| vitellogenin receptor [Oncorhynchus m... 229 5e-58
gi|3021536|emb|CAA05874.1| somatic lipoprotein receptor [Oncorhy... 229 7e-58
gi|17506619|ref|NP_492474.1| low density lipoprotein-related pro... 228 2e-57
gi|28502930|gb|AAH47187.1| Zgc:55792 protein [Danio rerio] 224 2e-56
gi|39581312|emb|CAE72333.1| Hypothetical protein CBG19478 [Caeno... 224 3e-56
gi|46561848|gb|AAT01141.1| proteoliaisin [Strongylocentrotus pur... 223 5e-56
gi|24158420|ref|NP_524643.2| CG7981-PA [Drosophila melanogaster]... 222 8e-56
gi|24639352|ref|NP_726813.1| CG7981-PC [Drosophila melanogaster]... 222 8e-56
gi|24639356|ref|NP_726815.1| CG7981-PD [Drosophila melanogaster]... 222 8e-56
gi|6946671|emb|CAB72286.1| EG:BACR25B3.1 [Drosophila melanogaster] 222 8e-56
gi|24639354|ref|NP_726814.1| CG7981-PE [Drosophila melanogaster]... 222 8e-56
gi|24639358|ref|NP_726816.1| CG7981-PB [Drosophila melanogaster]... 222 8e-56
gi|15425719|dbj|BAB64337.1| vitellogenin receptor [Anguilla japo... 221 2e-55
gi|3114861|emb|CAA72732.1| putative LR11/gp250 receptor protein ... 221 2e-55
gi|47224917|emb|CAG06487.1| unnamed protein product [Tetraodon n... 217 3e-54
gi|17298315|gb|AAL38107.1| candidate tumor suppressor protein [H... 216 5e-54
gi|7512093|pir||T30272 hypothetical protein - sea urchin (Strong... 216 8e-54
gi|47222148|emb|CAG11574.1| unnamed protein product [Tetraodon n... 213 5e-53
gi|46561854|gb|AAT01144.1| soft fertilization envelope protein 9... 211 3e-52
gi|34863171|ref|XP_217115.2| similar to gp250 precursor [Rattus ... 207 3e-51
gi|26332673|dbj|BAC30054.1| unnamed protein product [Mus musculus] 206 5e-51
gi|2135570|pir||I38467 low density lipoprotein-related protein 2... 201 2e-49
gi|47207800|emb|CAF96703.1| unnamed protein product [Tetraodon n... 201 2e-49
gi|18859115|ref|NP_571516.1| notch homolog 1a; neurogenic locus ... 197 4e-48
gi|34853095|ref|XP_342393.1| similar to Neurogenic locus notch h... 195 1e-47
gi|48134434|ref|XP_396734.1| similar to ENSANGP00000005397 [Apis... 192 9e-47
gi|31339070|dbj|BAC77039.1| transmembrane receptor Notch1 D [Mus... 192 1e-46
gi|15425721|dbj|BAB64338.1| vitellogenin receptor [Conger myrias... 192 1e-46
gi|31339069|dbj|BAC77038.1| transmembrane receptor Notch1 B [Mus... 192 1e-46
gi|31543332|ref|NP_032740.2| Notch gene homolog 1; Notch gene ho... 192 1e-46
gi|31339071|dbj|BAC77040.1| transmembrane receptor Notch1 [Mus m... 192 1e-46
gi|112074|pir||S18188 notch protein homolog - rat 192 1e-46
gi|6093542|sp|Q07008|NTC1_RAT Neurogenic locus notch homolog pro... 192 1e-46
gi|27894368|ref|NP_060087.2| notch1 preproprotein; translocation... 191 2e-46
gi|50757191|ref|XP_415420.1| PREDICTED: similar to receptor prot... 191 3e-46
gi|48095222|ref|XP_394385.1| similar to ENSANGP00000017849 [Apis... 189 1e-45
gi|4505017|ref|NP_002327.1| low density lipoprotein receptor-rel... 189 1e-45
gi|12231943|gb|AAG49316.1| notch-like transmembrane receptor [Ca... 188 2e-45
gi|40288425|gb|AAR84237.1| truncated epidermal growth factor (be... 187 2e-45
gi|38174481|gb|AAH60704.1| Low density lipoprotein receptor-rela... 187 2e-45
gi|4503491|ref|NP_001954.1| epidermal growth factor (beta-urogas... 187 2e-45
gi|50750994|ref|XP_422222.1| PREDICTED: similar to Neurogenic lo... 187 2e-45
gi|6678718|ref|NP_032540.1| low density lipoprotein receptor-rel... 187 3e-45
gi|31200521|ref|XP_309208.1| ENSANGP00000005397 [Anopheles gambi... 187 4e-45
gi|338675|gb|AAA60614.1| TAN1 187 4e-45
gi|6678716|ref|NP_032539.1| low density lipoprotein receptor-rel... 187 4e-45
gi|15030228|gb|AAH11374.1| Low density lipoprotein receptor-rela... 187 4e-45
gi|3831750|gb|AAC70183.1| LDL receptor member LR3 [Mus musculus] 187 4e-45
gi|7512094|pir||T30274 proteoliaisin - sea urchin (Strongylocent... 187 4e-45
gi|107215|pir||A40043 notch protein homolog TAN-1 precursor - human 187 4e-45
gi|20141565|sp|P46531|NTC1_HUMAN Neurogenic locus notch homolog ... 187 4e-45
gi|46947106|gb|AAB02256.2| SFE1 [Strongylocentrotus purpuratus] 187 4e-45
gi|26326125|dbj|BAC26806.1| unnamed protein product [Mus musculus] 186 5e-45
gi|85085|pir||A24420 notch protein - fruit fly (Drosophila melan... 186 5e-45
gi|24639454|ref|NP_476859.2| CG3936-PA [Drosophila melanogaster]... 186 5e-45
gi|4467343|emb|CAB37610.1| EG:140G11.1 [Drosophila melanogaster] 186 5e-45
gi|34861345|ref|XP_215187.2| similar to low density lipoprotein ... 186 7e-45
gi|47226733|emb|CAG07892.1| unnamed protein product [Tetraodon n... 186 9e-45
gi|1709335|sp|P21783|NOTC_XENLA Neurogenic locus notch protein h... 186 9e-45
gi|104252|pir||A35844 Xotch protein - African clawed frog 186 9e-45
gi|47213912|emb|CAF95854.1| unnamed protein product [Tetraodon n... 186 9e-45
gi|50657364|ref|NP_001002827.1| Notch homolog 4 [Rattus norvegic... 186 9e-45
gi|39583862|emb|CAE63952.1| Hypothetical protein CBG08534 [Caeno... 185 1e-44
gi|47217533|emb|CAG02460.1| unnamed protein product [Tetraodon n... 185 1e-44
gi|47522862|ref|NP_999185.1| epidermal growth factor [Sus scrofa... 185 1e-44
gi|33859592|ref|NP_035058.1| Notch gene homolog 2; Notch gene ho... 184 2e-44
gi|22854902|gb|AAN09806.1| lipoprotein receptor-related protein ... 184 2e-44
gi|157988|gb|AAB59220.1| Notch growth factor [Drosophila melanog... 184 2e-44
gi|1389670|gb|AAC36151.1| Notch homolog Scalloped wings [Lucilia... 184 2e-44
gi|7459690|pir||T09059 notch4 - mouse >gnl|BL_ORD_ID|1472155 gi|... 184 3e-44
gi|1401160|gb|AAC52630.1| Notch4 184 3e-44
gi|37620143|ref|NP_571624.2| notch homolog 5 [Danio rerio] >gnl|... 184 3e-44
gi|22854904|gb|AAN09807.1| lipoprotein receptor-related protein ... 184 3e-44
gi|6754874|ref|NP_035059.1| Notch gene homolog 4; Notch gene hom... 184 3e-44
gi|50747936|ref|XP_421046.1| PREDICTED: similar to low density l... 183 4e-44
gi|26005794|dbj|BAC41349.1| receptor protein Notch1 [Cynops pyrr... 182 7e-44
gi|47220032|emb|CAG12180.1| unnamed protein product [Tetraodon n... 182 7e-44
gi|14028618|gb|AAK52433.1| low density lipoprotein receptor-rela... 182 1e-43
gi|3831748|gb|AAC72791.1| LDL receptor member LR3 [Homo sapiens] 182 1e-43
gi|47117043|sp|O75197|LRP5_HUMAN Low-density lipoprotein recepto... 182 1e-43
gi|4505019|ref|NP_002326.1| low density lipoprotein receptor-rel... 182 1e-43
gi|46561852|gb|AAT01143.1| soft fertilization envelope protein 1... 182 1e-43
gi|3047267|gb|AAC14024.1| epidermal growth factor precursor [Sus... 182 1e-43
gi|6978797|ref|NP_036974.1| epidermal growth factor [Rattus norv... 181 2e-43
gi|20139103|sp|Q99466|NTC4_HUMAN Neurogenic locus notch homolog ... 181 2e-43
gi|1841543|gb|AAC63097.1| notch4 [Homo sapiens] 181 2e-43
gi|27894370|ref|NP_004548.2| notch4 preproprotein; Notch (Drosop... 181 2e-43
gi|22770986|gb|AAN06819.1| notch-like protein [Boophilus microplus] 181 2e-43
gi|1345964|sp|P10079|FBP1_STRPU Fibropellin I precursor (Epiderm... 180 4e-43
gi|25395755|pir||B88465 protein B0244.8 [imported] - Caenorhabdi... 180 5e-43
gi|32565544|ref|NP_498237.2| low density lipoprotein-receptor, c... 180 5e-43
gi|38303863|gb|AAH62030.1| Egf protein [Rattus norvegicus] 179 6e-43
gi|14009441|dbj|BAB47391.1| epidermal growth factor [Felis catus] 179 6e-43
gi|6760453|gb|AAF28358.1| LDL-related protein LRP6 [Drosophila m... 179 8e-43
gi|50801|emb|CAA24115.1| unnamed protein product [Mus musculus] 179 1e-42
gi|2209059|dbj|BAA20535.1| Notch 2 [Takifugu rubripes] 179 1e-42
gi|15418693|gb|AAF91072.1| arrow [Drosophila melanogaster] 179 1e-42
gi|24653390|ref|NP_524737.2| CG5912-PA [Drosophila melanogaster]... 179 1e-42
gi|223684|prf||0907234A epidermal growth factor precursor 179 1e-42
gi|38174492|gb|AAH60741.1| Epidermal growth factor [Mus musculus] 178 1e-42
gi|6753732|ref|NP_034243.1| epidermal growth factor [Mus musculu... 178 1e-42
gi|17389248|gb|AAH17681.1| Egf protein [Mus musculus] 178 1e-42
gi|31240653|ref|XP_320740.1| ENSANGP00000020132 [Anopheles gambi... 178 1e-42
gi|24041035|ref|NP_077719.2| notch 2 preproprotein; Notch (Droso... 177 2e-42
gi|11527997|gb|AAG37073.1| NOTCH2 protein [Homo sapiens] 177 2e-42
gi|20138948|sp|Q04721|NTC2_HUMAN Neurogenic locus notch homolog ... 177 2e-42
gi|13537341|dbj|BAB40599.1| epidermal growth factor [Canis famil... 177 2e-42
gi|1169995|sp|P46023|GPCR_LYMST G-protein coupled receptor GRL10... 177 4e-42
gi|1352528|sp|Q01705|NTC1_MOUSE Neurogenic locus notch homolog p... 177 4e-42
gi|13242247|ref|NP_077334.1| notch gene homolog 2 [Rattus norveg... 177 4e-42
gi|3065951|gb|AAC14346.1| Notch3 [Homo sapiens] 176 7e-42
gi|4557799|ref|NP_000426.1| Notch homolog 3; Notch (Drosophila) ... 176 7e-42
gi|3108187|gb|AAC15789.1| Notch 3 [Homo sapiens] 176 7e-42
gi|47209732|emb|CAF90682.1| unnamed protein product [Tetraodon n... 176 7e-42
gi|14278869|dbj|BAB59049.1| X-Serrate-1 protein [Xenopus laevis] 176 7e-42
gi|39645780|gb|AAH63815.1| Unknown (protein for MGC:74442) [Homo... 176 9e-42
gi|47211616|emb|CAF92929.1| unnamed protein product [Tetraodon n... 176 9e-42
gi|1754627|dbj|BAA13116.1| notch related protein [Homo sapiens] 176 9e-42
gi|161466|gb|AAA62163.1| fibropellin Ib 174 2e-41
gi|33879163|gb|AAH21204.1| Unknown (protein for IMAGE:4110815) [... 174 3e-41
gi|18535661|gb|AAL71862.1| delta protein [Strongylocentrotus pur... 174 3e-41
gi|2313049|dbj|BAA21713.1| C-Serrate-2 [Gallus gallus] 174 3e-41
gi|7522619|pir||T30201 Notch homolog protein - sea squirt (Haloc... 173 4e-41
gi|47221469|emb|CAG08131.1| unnamed protein product [Tetraodon n... 173 4e-41
gi|47938096|gb|AAH71562.1| NOTCH2 protein [Homo sapiens] 173 4e-41
gi|17554424|ref|NP_498537.1| low density lipoprotein-receptor, c... 173 6e-41
gi|9966775|ref|NP_064472.2| Notch 3 [Rattus norvegicus] >gnl|BL_... 173 6e-41
gi|39589754|emb|CAE66989.1| Hypothetical protein CBG12386 [Caeno... 173 6e-41
gi|29837359|gb|AAP05764.1| notch-like transmembrane receptor LIN... 172 8e-41
gi|29244926|ref|NP_006578.2| corin; heart specific serine protei... 172 1e-40
gi|6681362|dbj|BAA88688.1| MEGF7 [Rattus norvegicus] 172 1e-40
gi|4504549|ref|NP_002151.1| tenascin C (hexabrachion); Hexabrach... 171 2e-40
gi|12057020|emb|CAC19873.1| putative notch receptor protein [Bra... 171 2e-40
gi|7512075|pir||T31070 notch homolog - sea urchin (Lytechinus va... 171 2e-40
gi|13878447|sp|Q9Y5Q5|CORI_HUMAN Atrial natriuteric peptide-conv... 171 2e-40
gi|477532|pir||A49175 Motch B protein - mouse (fragment) >gnl|BL... 171 2e-40
gi|499686|gb|AAA29995.1| fibropellin Ia 171 2e-40
gi|48110771|ref|XP_396277.1| similar to CG9138-PA [Apis mellifera] 171 2e-40
gi|117422|sp|P10040|CRB_DROME Crumbs protein precursor (95F) >gn... 171 2e-40
gi|6679096|ref|NP_032742.1| Notch gene homolog 3; Notch gene hom... 171 3e-40
gi|184484|gb|AAA88083.1| hexabrachion 171 3e-40
gi|2569972|emb|CAA71380.1| Notch receptor protein [Danio rerio] 170 4e-40
gi|6689350|emb|CAB65469.1| signal receptor protein [Tribolium ca... 170 4e-40
gi|930024|emb|CAA30824.1| tenascin [Gallus gallus] 170 5e-40
gi|34866738|ref|XP_236755.2| similar to testis protein TEX15 [Ra... 169 8e-40
gi|12055236|emb|CAC20782.1| fibrosurfin [Paracentrotus lividus] 169 8e-40
gi|18535657|gb|AAL71861.1| delta protein [Lytechinus variegatus] 169 8e-40
gi|41053668|ref|NP_956782.1| hypothetical protein MGC63759 [Dani... 169 1e-39
gi|212747|gb|AAA49084.1| 200 kd tenascin precursor 169 1e-39
gi|212748|gb|AAA49085.1| 190 kd tenascin precursor 169 1e-39
gi|45382035|ref|NP_990787.1| 200 kd tenascin [Gallus gallus] >gn... 169 1e-39
gi|37360112|dbj|BAC98034.1| mKIAA0816 protein [Mus musculus] 168 1e-39
gi|37227|emb|CAA39628.1| tenascin [Homo sapiens] 168 1e-39
gi|6685453|sp|Q25464|FP2_MYTGA Adhesive plaque matrix protein 2 ... 168 2e-39
gi|1438937|gb|AAB39007.1| transmembrane protein Jagged 1 [Homo s... 167 2e-39
gi|4557679|ref|NP_000205.1| jagged 1 precursor; jagged1 (Alagill... 167 2e-39
gi|2130537|gb|AAC51323.1| transmembrane protein Jagged [Homo sap... 167 2e-39
gi|47604934|ref|NP_001001292.1| epidermal growth factor precurso... 167 2e-39
gi|47210424|emb|CAF92449.1| unnamed protein product [Tetraodon n... 167 4e-39
gi|477327|pir||A48825 Notch homolog Motch protein - mouse (fragm... 166 5e-39
gi|50756141|ref|XP_415035.1| PREDICTED: similar to C-Serate-1 pr... 166 7e-39
gi|1236281|emb|CAA64604.1| C-Serate-1 protein [Gallus gallus] 166 7e-39
gi|7106435|ref|NP_035737.1| tenascin C [Mus musculus] >gnl|BL_OR... 166 7e-39
gi|2228793|gb|AAC51731.1| Jagged1 [Homo sapiens] 166 9e-39
gi|50746773|ref|XP_420648.1| PREDICTED: similar to epidermal gro... 166 9e-39
gi|24582396|ref|NP_609091.2| CG9138-PA [Drosophila melanogaster]... 165 1e-38
gi|29290612|emb|CAD83048.1| bN144L11.1.2 (tenascin C, variant 2)... 165 1e-38
gi|15213703|gb|AAK92130.1| EGF-like protein [Podocoryne carnea] 165 1e-38
gi|91806|pir||JQ1322 tenascin precursor - mouse >gnl|BL_ORD_ID|1... 165 1e-38
gi|29290613|emb|CAD83049.1| bN144L11.1.3 (tenascin C, variant 3)... 165 1e-38
gi|18858915|ref|NP_571938.1| jagged 1b; jagged3 [Danio rerio] >g... 165 2e-38
gi|7305197|ref|NP_038850.1| jagged 1 [Mus musculus] >gnl|BL_ORD_... 165 2e-38
gi|7542565|gb|AAF63500.1| SP1070 [Drosophila melanogaster] 165 2e-38
gi|104643|pir||A32230 tenascin precursor - chicken >gnl|BL_ORD_I... 165 2e-38
gi|9506825|ref|NP_062020.1| jagged 1 [Rattus norvegicus] >gnl|BL... 165 2e-38
gi|14488690|pdb|1IJQ|A Chain A, Crystal Structure Of The Ldl Rec... 165 2e-38
gi|1083702|pir||A56136 jagged protein precursor - rat 165 2e-38
gi|13177625|gb|AAK14898.1| Motch [Mus musculus] 164 2e-38
gi|29837357|gb|AAP05763.1| notch-like transmembrane receptor LIN... 164 2e-38
gi|17553810|ref|NP_499014.1| notch-like transmembrane receptor, ... 164 4e-38
gi|283790|pir||A43902 tenascin - eastern newt (fragment) 164 4e-38
gi|47216575|emb|CAG00610.1| unnamed protein product [Tetraodon n... 163 6e-38
gi|552087|gb|AAA28428.1| crumbs protein 163 6e-38
gi|24649628|ref|NP_524480.2| CG6383-PA [Drosophila melanogaster]... 163 6e-38
gi|31202969|ref|XP_310433.1| ENSANGP00000017849 [Anopheles gambi... 162 8e-38
gi|17551262|ref|NP_510822.1| drosophila CRumBs homolog (crb-1) [... 162 1e-37
gi|2605947|gb|AAB84216.1| hJAG2.del-E6 [Homo sapiens] 161 2e-37
gi|32563562|ref|NP_872279.1| corin [Rattus norvegicus] >gnl|BL_O... 161 2e-37
gi|17554212|ref|NP_499007.1| abnormal cell LINeage LIN-12, notch... 160 3e-37
gi|28195400|ref|NP_777131.1| SCO-spondin [Bos taurus] >gnl|BL_OR... 160 3e-37
gi|47214982|emb|CAG01316.1| unnamed protein product [Tetraodon n... 160 3e-37
gi|42658662|ref|XP_379966.1| similar to KIAA2036 protein [Homo s... 160 4e-37
gi|21704279|ref|NP_660142.1| jagged 2 isoform b precursor [Homo ... 160 5e-37
gi|31212883|ref|XP_312182.1| ENSANGP00000010271 [Anopheles gambi... 160 5e-37
gi|34879554|ref|XP_238019.2| similar to MEGF10 protein [Rattus n... 160 5e-37
gi|48120148|ref|XP_393220.1| similar to EG:BACR25B3.1 [Apis mell... 159 7e-37
gi|26330916|dbj|BAC29188.1| unnamed protein product [Mus musculus] 159 9e-37
gi|8394057|ref|NP_058565.1| corin; low density lipoprotein-relat... 159 9e-37
gi|50731507|ref|XP_417286.1| PREDICTED: similar to low density l... 159 1e-36
gi|30424661|ref|NP_775604.1| subcommissural organ spondin; SCO-s... 159 1e-36
gi|12231947|gb|AAG49318.1| notch-like transmembrane receptor [Ca... 159 1e-36
gi|39585030|emb|CAE62681.1| Hypothetical protein CBG06826 [Caeno... 158 1e-36
gi|18044366|gb|AAH20198.1| MEGF10 protein [Homo sapiens] 158 2e-36
gi|29568116|gb|AAO41836.1| secreted protein SST3 [Mus musculus] 158 2e-36
gi|40254325|ref|NP_766051.3| secreted protein SST3 [Mus musculus... 158 2e-36
gi|47523544|ref|NP_999395.1| tenascin C; hexabrachion [Sus scrof... 157 3e-36
gi|28850442|gb|AAO53206.1| similar to Mus musculus (Mouse). Tena... 157 3e-36
gi|24940349|emb|CAD45189.1| Notch protein [Cupiennius salei] 157 3e-36
gi|21686991|ref|NP_571937.1| jagged 2 isoform 1; serrateB; jagge... 157 3e-36
gi|21687165|ref|NP_571740.1| jagged 2 isoform 2; serrateB; jagge... 157 3e-36
gi|45124835|emb|CAF33425.1| SCO-spondin [Rattus norvegicus] 157 3e-36
gi|3808095|emb|CAA69867.1| SCO-spondin [Bos taurus] 157 3e-36
gi|21553297|ref|NP_034718.1| jagged 2; syndactylism [Mus musculu... 157 4e-36
gi|2197067|gb|AAB61285.1| Jagged 2 [Homo sapiens] 157 4e-36
gi|20138797|sp|Q9Y219|JAG2_HUMAN Jagged 2 precursor (Jagged2) (H... 157 4e-36
gi|21704277|ref|NP_002217.3| jagged 2 isoform a precursor [Homo ... 157 4e-36
gi|2432002|gb|AAB71189.1| Jagged 2 [Homo sapiens] 157 4e-36
gi|552260|gb|AAA30050.1| putative epidermal growth factor [Stron... 156 6e-36
gi|2804289|dbj|BAA24436.1| tenascin-X [Mus musculus] 156 6e-36
gi|31208143|ref|XP_313038.1| ENSANGP00000011235 [Anopheles gambi... 156 7e-36
gi|50747079|ref|XP_426340.1| PREDICTED: similar to Atrial natriu... 156 7e-36
gi|38083736|ref|XP_145186.3| similar to Neurogenic locus Notch p... 155 1e-35
gi|2765402|emb|CAA74706.1| jagged2 protein [Homo sapiens] 154 2e-35
gi|34877671|ref|XP_237415.2| similar to secreted protein SST3 [R... 154 2e-35
gi|15799278|gb|AAL08215.1| jagged2 [Danio rerio] 154 2e-35
gi|47228422|emb|CAG05242.1| unnamed protein product [Tetraodon n... 154 3e-35
gi|4321121|gb|AAB17010.2| Notch-3 homolog [Carassius auratus] 154 4e-35
gi|13928672|ref|NP_112453.1| tenascin XB [Mus musculus] >gnl|BL_... 154 4e-35
gi|34935270|ref|XP_343120.1| jagged 2 [Rattus norvegicus] 152 8e-35
gi|18676472|dbj|BAB84888.1| FLJ00133 protein [Homo sapiens] 152 8e-35
gi|47230241|emb|CAG10655.1| unnamed protein product [Tetraodon n... 152 8e-35
gi|37549557|ref|XP_059482.4| FLJ00133 protein [Homo sapiens] 152 8e-35
gi|50751224|ref|XP_429288.1| PREDICTED: hypothetical protein XP_... 152 1e-34
gi|34858529|ref|XP_232466.2| similar to low density lipoprotein ... 150 3e-34
gi|12248891|dbj|BAB20317.1| notch4 [Homo sapiens] 150 3e-34
gi|14192943|ref|NP_115822.1| MEGF10 protein [Homo sapiens] >gnl|... 150 5e-34
gi|38426901|gb|AAR20495.1| secretory protein Crb1s [Mus musculus] 149 7e-34
gi|39585129|emb|CAE62780.1| Hypothetical protein CBG06951 [Caeno... 149 7e-34
gi|24940351|emb|CAD45190.1| Delta1 protein [Cupiennius salei] 149 9e-34
gi|6912322|ref|NP_036208.1| crumbs homolog 1 isoform I precursor... 149 9e-34
gi|41327708|ref|NP_957705.1| crumbs homolog 1 isoform II precurs... 149 9e-34
gi|37360934|dbj|BAC98376.1| KIAA2036 protein [Homo sapiens] 149 1e-33
gi|42657977|ref|XP_376719.1| similar to KIAA2036 protein [Homo s... 149 1e-33
gi|47228921|emb|CAG09436.1| unnamed protein product [Tetraodon n... 149 1e-33
gi|20138454|sp|P97607|JAG2_RAT Jagged 2 (Jagged2) >gnl|BL_ORD_ID... 148 2e-33
gi|47225870|emb|CAF98350.1| unnamed protein product [Tetraodon n... 148 2e-33
gi|2765414|emb|CAA74835.1| jagged2 protein [Mus musculus] 148 2e-33
gi|50233828|ref|NP_001001979.1| RIKEN cDNA 3000002B06 [Mus muscu... 148 2e-33
gi|18875406|ref|NP_573502.1| crumbs homolog 1 [Mus musculus] >gn... 148 2e-33
gi|39588983|emb|CAE69613.1| Hypothetical protein CBG15845 [Caeno... 147 3e-33
gi|47216760|emb|CAG03764.1| unnamed protein product [Tetraodon n... 147 3e-33
gi|48097592|ref|XP_393831.1| similar to delta protein [Apis mell... 147 3e-33
gi|42657851|ref|XP_371878.2| similar to Neurogenic locus notch h... 147 3e-33
gi|42658225|ref|XP_374405.2| similar to Neurogenic locus notch h... 147 3e-33
gi|50749062|ref|XP_426470.1| PREDICTED: similar to C-Serrate-2 [... 147 4e-33
gi|48095930|ref|XP_394560.1| similar to C-Serate-1 protein [Apis... 147 4e-33
gi|45387869|ref|NP_991294.1| epidermal growth factor precursor [... 147 4e-33
gi|49022876|dbj|BAC65837.2| mKIAA1781 protein [Mus musculus] 146 6e-33
gi|14042419|dbj|BAB55237.1| unnamed protein product [Homo sapiens] 146 6e-33
gi|539698|pir||A40701 tenascin-X precursor - human 146 8e-33
gi|20544189|ref|NP_061978.4| tenascin XB isoform 1; tenascin XB1... 146 8e-33
gi|34856705|ref|XP_230472.2| similar to notch ligand DLL4 [Rattu... 146 8e-33
gi|394780|emb|CAA50739.1| tenascin-X precursor [Homo sapiens] 146 8e-33
gi|31236662|ref|XP_319454.1| ENSANGP00000002886 [Anopheles gambi... 145 1e-32
gi|27807269|ref|NP_777128.1| tenascin X [Bos taurus] >gnl|BL_ORD... 145 1e-32
gi|39596035|emb|CAE69671.1| Hypothetical protein CBG15921 [Caeno... 145 1e-32
gi|3057059|gb|AAC14010.1| Jagged 2 protein [Mus musculus] 144 2e-32
gi|17507659|ref|NP_492397.1| notch (1J467) [Caenorhabditis elega... 144 2e-32
gi|7510359|pir||T27283 hypothetical protein Y64G10A.f - Caenorha... 143 5e-32
gi|27369722|ref|NP_766110.1| RIKEN cDNA 2410080H04 [Mus musculus... 143 5e-32
gi|7670249|dbj|BAA95001.1| secretory protein containing EGF doma... 142 8e-32
gi|25295761|pir||JC7569 Delta-4 protein - mouse >gnl|BL_ORD_ID|3... 142 8e-32
gi|18858913|ref|NP_571936.1| jagged 1a; jagged1 [Danio rerio] >g... 142 8e-32
gi|9506547|ref|NP_062327.1| delta-like 4 [Mus musculus] >gnl|BL_... 142 1e-31
gi|8705244|gb|AAF78785.1| notch ligand [Mus musculus] 142 1e-31
gi|7671639|emb|CAB89296.1| dJ34F7.1.1 (tenascin XB (isoform 1)) ... 142 1e-31
gi|50747938|ref|XP_421047.1| PREDICTED: similar to Lipoprotein R... 142 1e-31
gi|39581624|emb|CAE71745.1| Hypothetical protein CBG18730 [Caeno... 142 1e-31
gi|50744826|ref|XP_419893.1| PREDICTED: similar to receptor prot... 141 2e-31
gi|39593249|emb|CAE64719.1| Hypothetical protein CBG09505 [Caeno... 141 2e-31
gi|50510649|dbj|BAD32310.1| mKIAA0815 protein [Mus musculus] 140 3e-31
gi|46395763|sp|Q80V70|EFL3_MOUSE Multiple EGF-like-domain protei... 140 3e-31
gi|14091746|ref|NP_114452.1| delta-like 1; delta (Drosophila)-li... 140 3e-31
gi|22779881|ref|NP_082736.1| Jedi [Mus musculus] >gnl|BL_ORD_ID|... 140 4e-31
gi|50759167|ref|XP_417548.1| PREDICTED: similar to MEGF6 [Gallus... 140 4e-31
gi|27503754|gb|AAH42490.1| 3110045G13Rik protein [Mus musculus] 140 5e-31
gi|38489655|gb|AAR21463.1| delta protein [Drosophila melanogaster] 140 5e-31
gi|38489575|gb|AAR21453.1| delta protein [Drosophila melanogaste... 140 5e-31
gi|17543898|ref|NP_502737.1| MEGF6 (4P83) [Caenorhabditis elegan... 139 7e-31
gi|47209058|emb|CAF90766.1| unnamed protein product [Tetraodon n... 139 7e-31
gi|47217532|emb|CAG02459.1| unnamed protein product [Tetraodon n... 139 9e-31
gi|17137388|ref|NP_477264.1| CG3619-PA [Drosophila melanogaster]... 139 9e-31
gi|38489599|gb|AAR21456.1| delta protein [Drosophila melanogaster] 139 9e-31
gi|38489663|gb|AAR21464.1| delta protein [Drosophila melanogaster] 139 9e-31
gi|38489583|gb|AAR21454.1| delta protein [Drosophila melanogaster] 139 9e-31
gi|38489639|gb|AAR21461.1| delta protein [Drosophila melanogaster] 139 9e-31
gi|103172|pir||S19087 gene Delta protein precursor - fruit fly (... 139 9e-31
gi|577774|emb|CAA68369.1| delta protein [Drosophila melanogaster] 139 9e-31
gi|17542742|ref|NP_500460.1| SP1070 (4E777) [Caenorhabditis eleg... 139 1e-30
gi|17386053|gb|AAL38571.1| Jedi protein [Mus musculus] 139 1e-30
gi|84963|pir||S00670 neurogenic repetitive locus delta protein p... 139 1e-30
gi|33239429|ref|NP_690012.1| Jedi soluble isoform 736; Jedi [Mus... 139 1e-30
gi|38489591|gb|AAR21455.1| delta protein [Drosophila melanogaste... 139 1e-30
gi|85076|pir||A31246 neurogenic protein Delta precursor - fruit ... 139 1e-30
gi|15291287|gb|AAK92912.1| GH14506p [Drosophila melanogaster] 138 2e-30
gi|6739500|gb|AAF27280.1| LDLR-FUT fusion protein [Homo sapiens] 138 2e-30
gi|48095607|ref|XP_392328.1| similar to ENSANGP00000021850 [Apis... 138 2e-30
gi|47219156|emb|CAG01819.1| unnamed protein product [Tetraodon n... 138 2e-30
gi|46249844|gb|AAH68636.1| Unknown (protein for MGC:79882) [Xeno... 137 3e-30
gi|40789272|ref|NP_031891.2| delta-like 1 [Mus musculus] >gnl|BL... 137 4e-30
gi|2494282|sp|Q61483|DLL1_MOUSE Delta-like protein 1 precursor (... 137 4e-30
gi|48109148|ref|XP_396216.1| similar to ENSANGP00000007871 [Apis... 137 5e-30
gi|17562774|ref|NP_506228.1| NIDogen, basement membrane protein ... 137 5e-30
gi|9506545|ref|NP_061947.1| delta-like 4 protein precursor; delt... 137 5e-30
gi|8926615|gb|AAF81912.1| delta 4 [Homo sapiens] 137 5e-30
gi|47229848|emb|CAG07044.1| unnamed protein product [Tetraodon n... 136 6e-30
gi|14192941|ref|NP_115821.1| MEGF11 protein [Homo sapiens] >gnl|... 136 8e-30
gi|47229014|emb|CAG09529.1| unnamed protein product [Tetraodon n... 136 8e-30
gi|225779|prf||1313229A neurogenic gene delta 136 8e-30
gi|41107704|ref|XP_031401.4| EGF-like-domain, multiple 3 [Homo s... 135 1e-29
gi|47211801|emb|CAF92489.1| unnamed protein product [Tetraodon n... 135 1e-29
gi|50761405|ref|XP_424719.1| PREDICTED: similar to MEGF10 protei... 135 1e-29
gi|31199197|ref|XP_308546.1| ENSANGP00000015891 [Anopheles gambi... 135 1e-29
gi|23477350|gb|AAN34647.1| LDL receptor [Oncorhynchus mykiss] 135 2e-29
gi|46395624|sp|O75095|EFL3_HUMAN Multiple EGF-like-domain protei... 134 2e-29
gi|34853938|ref|XP_345348.1| similar to 5930402A21 protein [Ratt... 134 2e-29
gi|7677011|emb|CAB89569.1| dJ894D12.3 (delta-like 1 (mouse) homo... 134 3e-29
gi|25143262|ref|NP_740922.1| CEll Death abnormality CED-1, cell ... 134 3e-29
gi|19571666|emb|CAD27615.1| Hypothetical protein Y47H9C.4c [Caen... 134 3e-29
gi|19571665|emb|CAD27614.1| Hypothetical protein Y47H9C.4b [Caen... 134 3e-29
gi|41188798|ref|XP_371320.1| similar to MEGF12 [Homo sapiens] 134 4e-29
gi|24655537|ref|NP_728660.1| CG2086-PB [Drosophila melanogaster]... 134 4e-29
gi|34857914|ref|XP_215648.2| similar to MEGF12 [Rattus norvegicus] 134 4e-29
>gi|17509113|ref|NP_491270.1| lipoprotein receptor-related protein
(1E504) [Caenorhabditis elegans]
gi|15011834|gb|AAB54138.2| Hypothetical protein T21E3.3
[Caenorhabditis elegans]
Length = 2192
Score = 4685 bits (12153), Expect = 0.0
Identities = 2148/2192 (97%), Positives = 2148/2192 (97%)
Frame = -1
Query: 6579 MFDDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCTCNENEFRCQS 6400
MFDDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCTCNENEFRCQS
Sbjct: 1 MFDDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCTCNENEFRCQS 60
Query: 6399 GACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDGT 6220
GACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDGT
Sbjct: 61 GACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDGT 120
Query: 6219 NDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADGS 6040
NDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADGS
Sbjct: 121 NDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADGS 180
Query: 6039 DEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNATFRC 5860
DEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNATFRC
Sbjct: 181 DEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNATFRC 240
Query: 5859 TNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACELTAVL 5680
TNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACELTAVL
Sbjct: 241 TNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACELTAVL 300
Query: 5679 CDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASVDCVDGSDEWVEICS 5500
CDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASVDCVDGSDEWVEICS
Sbjct: 301 CDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASVDCVDGSDEWVEICS 360
Query: 5499 LSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSSTRNSCD 5320
LSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSSTRNSCD
Sbjct: 361 LSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSSTRNSCD 420
Query: 5319 QTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKANCSHFCIDRRDVGHQCFCAPG 5140
QTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKANCSHFCIDRRDVGHQCFCAPG
Sbjct: 421 QTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKANCSHFCIDRRDVGHQCFCAPG 480
Query: 5139 YILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLTNGVALDYDVKSDLV 4960
YILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLTNGVALDYDVKSDLV
Sbjct: 481 YILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLTNGVALDYDVKSDLV 540
Query: 4959 YWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVC 4780
YWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVC
Sbjct: 541 YWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVC 600
Query: 4779 DMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRT 4600
DMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRT
Sbjct: 601 DMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRT 660
Query: 4599 IRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWS 4420
IRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWS
Sbjct: 661 IRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWS 720
Query: 4419 DWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDN 4240
DWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDN
Sbjct: 721 DWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDN 780
Query: 4239 LCIPANTPDLTTSSDNFTCMCAQGFRSEGRSCVSECKPNDFVCTKTYKCISSWWRXXXXX 4060
LCIPANTPDLTTSSDNFTCMCAQGFRSEGRSCVSECKPNDFVCTKTYKCISSWWR
Sbjct: 781 LCIPANTPDLTTSSDNFTCMCAQGFRSEGRSCVSECKPNDFVCTKTYKCISSWWRCDGQD 840
Query: 4059 XXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEP 3880
GYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEP
Sbjct: 841 DCGDGEDEGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEP 900
Query: 3879 AFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCKPDFFACFNGTA 3700
AFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCKPDFFACFNGTA
Sbjct: 901 AFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCKPDFFACFNGTA 960
Query: 3699 ISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQCDGTLDCRD 3520
ISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQCDGTLDCRD
Sbjct: 961 ISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQCDGTLDCRD 1020
Query: 3519 GSDEKGCKKECAIVCDNSCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKENRKCGGFA 3340
GSDEKGCKKECAIVCDNSCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKENRKCGGFA
Sbjct: 1021 GSDEKGCKKECAIVCDNSCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKENRKCGGFA 1080
Query: 3339 CDGIVDCEDGSDEKGCPDLECHLASNKSLICDGTIDCSSGKDENNCHNNGESNFFQCSMQ 3160
CDGIVDCEDGSDEKGCPDLECHLASNKSLICDGTIDCSSGKDENNCHNNGESNFFQCSMQ
Sbjct: 1081 CDGIVDCEDGSDEKGCPDLECHLASNKSLICDGTIDCSSGKDENNCHNNGESNFFQCSMQ 1140
Query: 3159 TIKEWQVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFD 2980
TIKEWQVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFD
Sbjct: 1141 TIKEWQVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFD 1200
Query: 2979 GSDENPIHCKDMCKGKYRCTNGRCIDVSARXXXXXXXXXXXXXXXXGAECHHFGVCAQKC 2800
GSDENPIHCKDMCKGKYRCTNGRCIDVSAR GAECHHFGVCAQKC
Sbjct: 1201 GSDENPIHCKDMCKGKYRCTNGRCIDVSARCDGRDDCGDGSDEDTCGAECHHFGVCAQKC 1260
Query: 2799 WMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQVSVLRPVF 2620
WMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQVSVLRPVF
Sbjct: 1261 WMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQVSVLRPVF 1320
Query: 2619 NIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGLITY 2440
NIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGLITY
Sbjct: 1321 NIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGLITY 1380
Query: 2439 DFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLI 2260
DFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLI
Sbjct: 1381 DFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLI 1440
Query: 2259 FWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDV 2080
FWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDV
Sbjct: 1441 FWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDV 1500
Query: 2079 LKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITRQGSIHRMHKFTGKTNKYV 1900
LKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITRQGSIHRMHKFTGKTNKYV
Sbjct: 1501 LKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITRQGSIHRMHKFTGKTNKYV 1560
Query: 1899 QKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLCG 1720
QKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLCG
Sbjct: 1561 QKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLCG 1620
Query: 1719 PGRFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCSPQKTCVCPPGFYGRQCEINECSE 1540
PGRFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCSPQKTCVCPPGFYGRQCEINECSE
Sbjct: 1621 PGRFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCSPQKTCVCPPGFYGRQCEINECSE 1680
Query: 1539 TCWNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHCR 1360
TCWNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHCR
Sbjct: 1681 TCWNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHCR 1740
Query: 1359 SYSFCECDKGWTGPHCRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQNCV 1180
SYSFCECDKGWTGPHCRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQNCV
Sbjct: 1741 SYSFCECDKGWTGPHCRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQNCV 1800
Query: 1179 GHECLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPIT 1000
GHECLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPIT
Sbjct: 1801 GHECLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPIT 1860
Query: 999 CSCEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDD 820
CSCEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDD
Sbjct: 1861 CSCEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDD 1920
Query: 819 YCTNNSKCTITNGTHFECDCKPGFKGLRCEQETKCSECSNEAKCIKKPSGTVICQCPQGL 640
YCTNNSKCTITNGTHFECDCKPGFKGLRCEQETKCSECSNEAKCIKKPSGTVICQCPQGL
Sbjct: 1921 YCTNNSKCTITNGTHFECDCKPGFKGLRCEQETKCSECSNEAKCIKKPSGTVICQCPQGL 1980
Query: 639 GGEYCEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCLH 460
GGEYCEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCLH
Sbjct: 1981 GGEYCEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCLH 2040
Query: 459 DGNCTLDEYFEPQCECYQAFIGDRCQYRIHQHAVIFSDDDSGWIKSFXXXXXXXXXXXXX 280
DGNCTLDEYFEPQCECYQAFIGDRCQYRIHQHAVIFSDDDSGWIKSF
Sbjct: 2041 DGNCTLDEYFEPQCECYQAFIGDRCQYRIHQHAVIFSDDDSGWIKSFVVLAIILVTIVIV 2100
Query: 279 XXIFANRSNRFAVFRQFRHNPLQNQGAPVDQFSNPAYLIDEGGIELVTQNTSLVSSHDRG 100
IFANRSNRFAVFRQFRHNPLQNQGAPVDQFSNPAYLIDEGGIELVTQNTSLVSSHDRG
Sbjct: 2101 VGIFANRSNRFAVFRQFRHNPLQNQGAPVDQFSNPAYLIDEGGIELVTQNTSLVSSHDRG 2160
Query: 99 SFNNPVFEQEMVPIYNDTVENHELLPNNRSSN 4
SFNNPVFEQEMVPIYNDTVENHELLPNNRSSN
Sbjct: 2161 SFNNPVFEQEMVPIYNDTVENHELLPNNRSSN 2192
>gi|7508146|pir||T29764 hypothetical protein T21E3.3 - Caenorhabditis
elegans
Length = 2180
Score = 4512 bits (11703), Expect = 0.0
Identities = 2088/2193 (95%), Positives = 2098/2193 (95%), Gaps = 1/2193 (0%)
Frame = -1
Query: 6579 MFDDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCTCNENEFRCQS 6400
MFDDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCTCNENEFRCQS
Sbjct: 1 MFDDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCTCNENEFRCQS 60
Query: 6399 GACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDGT 6220
GACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDGT
Sbjct: 61 GACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDGT 120
Query: 6219 NDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADGS 6040
NDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADGS
Sbjct: 121 NDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADGS 180
Query: 6039 DEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNATFRC 5860
DEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNATFRC
Sbjct: 181 DEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNATFRC 240
Query: 5859 TNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACELTAVL 5680
TNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACELTAVL
Sbjct: 241 TNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACELTAVL 300
Query: 5679 CDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASVDCVDGSDEWVEICS 5500
CDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASVDCVDGSDEWVEICS
Sbjct: 301 CDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASVDCVDGSDEWVEICS 360
Query: 5499 LSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSSTRNSCD 5320
LSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSSTRNSCD
Sbjct: 361 LSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSSTRNSCD 420
Query: 5319 QTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKANCSHFCIDRRDVGHQCFCAPG 5140
QTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKANCSHFCIDRRDVGHQCFCAPG
Sbjct: 421 QTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKANCSHFCIDRRDVGHQCFCAPG 480
Query: 5139 YILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLTNGVALDYDVKSDLV 4960
YILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLTNGVALDYDVKSDLV
Sbjct: 481 YILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLTNGVALDYDVKSDLV 540
Query: 4959 YWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVC 4780
YWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVC
Sbjct: 541 YWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVC 600
Query: 4779 DMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRT 4600
DMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRT
Sbjct: 601 DMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRT 660
Query: 4599 IRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWS 4420
IRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWS
Sbjct: 661 IRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWS 720
Query: 4419 DWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDN 4240
DWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDN
Sbjct: 721 DWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDN 780
Query: 4239 LCIPANTPDLTTSSDNFTCMCAQGFRSEGRSCVSECKPNDFVCTKTYKCISSWWRXXXXX 4060
LCIPANTPDLTTSSDNFTCMCAQGFRSEGRSCVSECKPNDFVCTKTYKCISSWWR
Sbjct: 781 LCIPANTPDLTTSSDNFTCMCAQGFRSEGRSCVSECKPNDFVCTKTYKCISSWWRCDGQD 840
Query: 4059 XXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEP 3880
GYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEP
Sbjct: 841 DCGDGEDEGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEP 900
Query: 3879 AFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCKPDFFACFNGTA 3700
AFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCKPDFFACFNGTA
Sbjct: 901 AFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCKPDFFACFNGTA 960
Query: 3699 ISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQCDGTLDCRD 3520
ISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQCDGTLDCRD
Sbjct: 961 ISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQCDGTLDCRD 1020
Query: 3519 GSDEKGCKKECAIVCDNSCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKENRKCGGFA 3340
GSDEKGCKKECAIVCDNSCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKENRKCGGFA
Sbjct: 1021 GSDEKGCKKECAIVCDNSCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKENRKCGGFA 1080
Query: 3339 CDGIVDCEDGSDEKGCPDLECHLASNKSLICDGTIDCSSGKDENNCHNNGESNFFQCSMQ 3160
CDGIVDCEDGSDEKGCPDLECHLASNKSLICDGTIDCSSGKDENNCHNNGESNFFQCSMQ
Sbjct: 1081 CDGIVDCEDGSDEKGCPDLECHLASNKSLICDGTIDCSSGKDENNCHNNGESNFFQCSMQ 1140
Query: 3159 TIKEWQVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFD 2980
TIKEWQVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFD
Sbjct: 1141 TIKEWQVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFD 1200
Query: 2979 GSDENPIHCKDMCKGKYRCTNGRCIDVSARXXXXXXXXXXXXXXXXGAECHHFGVCAQKC 2800
GSDENPIHCKDMCKGKYRCTNGRCIDVSAR GAECHHFGVCAQKC
Sbjct: 1201 GSDENPIHCKDMCKGKYRCTNGRCIDVSARCDGRDDCGDGSDEDTCGAECHHFGVCAQKC 1260
Query: 2799 WMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQVSVLRPVF 2620
WMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQVSVLRPVF
Sbjct: 1261 WMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQVSVLRPVF 1320
Query: 2619 NIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGLITY 2440
NIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGLITY
Sbjct: 1321 NIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGLITY 1380
Query: 2439 DFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLI 2260
DFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLI
Sbjct: 1381 DFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLI 1440
Query: 2259 FWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDV 2080
FWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDV
Sbjct: 1441 FWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDV 1500
Query: 2079 LKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITRQGSIHRMHKFTGKTNKYV 1900
LKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITRQGSIHRMHKFTGKTNKYV
Sbjct: 1501 LKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITRQGSIHRMHKFTGKTNKYV 1560
Query: 1899 QKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLCG 1720
QKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLCG
Sbjct: 1561 QKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLCG 1620
Query: 1719 PGRFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCSPQKTCVCPPGFYGRQCEINECSE 1540
PGRFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCSPQKTCVCPPGFYGRQCE+ S+
Sbjct: 1621 PGRFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCSPQKTCVCPPGFYGRQCELYFTSK 1680
Query: 1539 -TCWNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHC 1363
+ T ++ G +V ++ Q + + P V KD
Sbjct: 1681 YDVFKASTNVLRLAGMARHV--QFKNSDQQQMLSVTAPQTTLNPAAQQTFV---KD---- 1731
Query: 1362 RSYSFCECDKGWTGPHCRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQNC 1183
FCECDKGWTGPHCRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQNC
Sbjct: 1732 ----FCECDKGWTGPHCRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQNC 1787
Query: 1182 VGHECLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPI 1003
VGHECLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPI
Sbjct: 1788 VGHECLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPI 1847
Query: 1002 TCSCEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCD 823
TCSCEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCD
Sbjct: 1848 TCSCEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCD 1907
Query: 822 DYCTNNSKCTITNGTHFECDCKPGFKGLRCEQETKCSECSNEAKCIKKPSGTVICQCPQG 643
DYCTNNSKCTITNGTHFECDCKPGFKGLRCEQETKCSECSNEAKCIKKPSGTVICQCPQG
Sbjct: 1908 DYCTNNSKCTITNGTHFECDCKPGFKGLRCEQETKCSECSNEAKCIKKPSGTVICQCPQG 1967
Query: 642 LGGEYCEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCL 463
LGGEYCEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCL
Sbjct: 1968 LGGEYCEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCL 2027
Query: 462 HDGNCTLDEYFEPQCECYQAFIGDRCQYRIHQHAVIFSDDDSGWIKSFXXXXXXXXXXXX 283
HDGNCTLDEYFEPQCECYQAFIGDRCQYRIHQHAVIFSDDDSGWIKSF
Sbjct: 2028 HDGNCTLDEYFEPQCECYQAFIGDRCQYRIHQHAVIFSDDDSGWIKSFVVLAIILVTIVI 2087
Query: 282 XXXIFANRSNRFAVFRQFRHNPLQNQGAPVDQFSNPAYLIDEGGIELVTQNTSLVSSHDR 103
IFANRSNRFAVFRQFRHNPLQNQGAPVDQFSNPAYLIDEGGIELVTQNTSLVSSHDR
Sbjct: 2088 VVGIFANRSNRFAVFRQFRHNPLQNQGAPVDQFSNPAYLIDEGGIELVTQNTSLVSSHDR 2147
Query: 102 GSFNNPVFEQEMVPIYNDTVENHELLPNNRSSN 4
GSFNNPVFEQEMVPIYNDTVENHELLPNNRSSN
Sbjct: 2148 GSFNNPVFEQEMVPIYNDTVENHELLPNNRSSN 2180
>gi|39586294|emb|CAE66705.1| Hypothetical protein CBG12050
[Caenorhabditis briggsae]
Length = 4856
Score = 3833 bits (9941), Expect = 0.0
Identities = 1709/2200 (77%), Positives = 1909/2200 (86%), Gaps = 8/2200 (0%)
Frame = -1
Query: 6579 MFDDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCTCNENEFRCQS 6400
MFDDED KYCS+RVCRPGYF+CGNGLCI E KVCNR NDC NF DE+NCTC+++EF+C S
Sbjct: 2668 MFDDEDAKYCSSRVCRPGYFDCGNGLCISESKVCNRFNDCINFHDENNCTCSKSEFKCDS 2727
Query: 6399 GACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDGT 6220
G CIP + RCNH+QDCNDASDEIGCP+RNCS+L EFGM+ LINCA+TSQCIHPSWKCDGT
Sbjct: 2728 GNCIPGEDRCNHVQDCNDASDEIGCPYRNCSSLVEFGMSDLINCASTSQCIHPSWKCDGT 2787
Query: 6219 NDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADGS 6040
NDCYDGSDE DC VEFD GSVS PRSCD+ TQF CLATR CMP W+CDGQPDCADGS
Sbjct: 2788 NDCYDGSDELDCLVEFDFNKGSVSPPRSCDSATQFPCLATRNCMPNRWRCDGQPDCADGS 2847
Query: 6039 DEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNATFRC 5860
DE NC+ K C SFEF+CES+KKCIPLEQKCDGR DCP+GEDE+ C+TECDSK GN+TFRC
Sbjct: 2848 DEANCEQKACNSFEFTCESTKKCIPLEQKCDGRSDCPNGEDENSCDTECDSKNGNSTFRC 2907
Query: 5859 TNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACELTAVL 5680
TNHRCIPMAWRCDGTDDC+DNAKSLGSDE+DCA G+TSFHVPSRC DETCVVACELTAVL
Sbjct: 2908 TNHRCIPMAWRCDGTDDCLDNAKSLGSDEMDCAPGKTSFHVPSRCTDETCVVACELTAVL 2967
Query: 5679 CDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASVDCVDGSDEWVEICS 5500
CDGI+DC+DGFDE+NCASLDRQCK NEWMCDSGQCI+S LCD+SVDC+DGSDEWVEICS
Sbjct: 2968 CDGIKDCNDGFDEENCASLDRQCKLNEWMCDSGQCINSAHLCDSSVDCIDGSDEWVEICS 3027
Query: 5499 LSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSSTRNSCD 5320
LSEPP+RGCP+GWSC+L NGTIGCLQE QLCDGR+DCMSGIDEQCD PQGNCSS RNSC+
Sbjct: 3028 LSEPPKRGCPNGWSCVLKNGTIGCLQEHQLCDGRKDCMSGIDEQCDLPQGNCSSARNSCE 3087
Query: 5319 QTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKANCSHFCIDRRDVGHQCFCAPG 5140
Q WNC+R+AGFE+CSCD+G+HLSPYDK+TCLRSPSCPKANCSHFCIDRRDVGHQCFCAPG
Sbjct: 3088 QPWNCKRNAGFETCSCDEGFHLSPYDKRTCLRSPSCPKANCSHFCIDRRDVGHQCFCAPG 3147
Query: 5139 YILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLTNGVALDYDVKSDLV 4960
+ILS+NQ+DCRRNDTIE EILMV GHRLKLFTIDGHAKATLLSNLTNGVALDYDVKSDLV
Sbjct: 3148 FILSDNQRDCRRNDTIEPEILMVSGHRLKLFTIDGHAKATLLSNLTNGVALDYDVKSDLV 3207
Query: 4959 YWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVC 4780
YWTDV + GNKAGITSMSNQP TYR+INSLPTKGIDGIAVDWLGR+IYYTDRNHDAIAVC
Sbjct: 3208 YWTDVTNSGNKAGITSMSNQPYTYRIINSLPTKGIDGIAVDWLGRHIYYTDRNHDAIAVC 3267
Query: 4779 DMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRT 4600
DMRGRFNRILLKGTPLNDPRAIVLDP+QAL+FWTDWGASAHIGRMNMDGSNE +IL+DRT
Sbjct: 3268 DMRGRFNRILLKGTPLNDPRAIVLDPIQALLFWTDWGASAHIGRMNMDGSNEMIILEDRT 3327
Query: 4599 IRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWS 4420
IRWPNALAVDAPAQRLYFGDAHRDYIASCNYDG+KRRMVLR SVRHIFALAVFEDY+YWS
Sbjct: 3328 IRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGTKRRMVLRNSVRHIFALAVFEDYIYWS 3387
Query: 4419 DWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDN 4240
DWHNHTIERVHKITG NRKVLIQDKQYRPMGFK+VHPS Q+MGS+KTA+HPCSQPARCDN
Sbjct: 3388 DWHNHTIERVHKITGDNRKVLIQDKQYRPMGFKVVHPSFQNMGSMKTAKHPCSQPARCDN 3447
Query: 4239 LCIPANTPDLTTSSDNFTCMCAQGFRSEGRSCVSECKPNDFVCTKTYKCISSWWRXXXXX 4060
LCIPA++P+ FTCMCAQGFRS+GRSCVSECKPNDFVCTKTYKCI+SWWR
Sbjct: 3448 LCIPASSPEA------FTCMCAQGFRSDGRSCVSECKPNDFVCTKTYKCIASWWRCDGQD 3501
Query: 4059 XXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEP 3880
GYF++GVCP FPC GQF+C ++ +N TAQCLYASKLCDGVKDC G+DEE
Sbjct: 3502 DCGDGEDEGYFLKGVCPQFPCDPGQFLCPKSPRNTTAQCLYASKLCDGVKDCLEGEDEEK 3561
Query: 3879 AFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCKPDFFACFNGTA 3700
FCE+FECTE+QFKCGDKKKCIPLTSVCDKEKDCDDGSDE +CEI SCKPDFFAC N T
Sbjct: 3562 TFCEHFECTESQFKCGDKKKCIPLTSVCDKEKDCDDGSDERSCEIKSCKPDFFACVNETT 3621
Query: 3699 --ISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQCDGTLDC 3526
ISKCIPKEFYCDGEDDCP GQDEPD+CFGIGECTHEQFQC SGKCIPKRR+CDGT+DC
Sbjct: 3622 SQISKCIPKEFYCDGEDDCPNGQDEPDTCFGIGECTHEQFQCASGKCIPKRRKCDGTIDC 3681
Query: 3525 RDGSDEKGCKKECAIVCDNSCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKE-NRKCG 3349
RDGSDEKGCKKECAIVCDN CV ++LCDGK+KC G+DE+EEAC IK+L+EK R CG
Sbjct: 3682 RDGSDEKGCKKECAIVCDNECVPVEELCDGKRKCTHGTDEEEEACAIKKLMEKPVLRTCG 3741
Query: 3348 GFACDGIVDCEDGSDEKGCPDLECHLASNKSLICDGTIDCSSGKDENNCHNNG--ESNFF 3175
GF CDGI+DCEDG+DEKGCPDLECHL++N SLICDG +DC SGKDE NC N G + F
Sbjct: 3742 GFKCDGIIDCEDGADEKGCPDLECHLSNNASLICDGKVDCESGKDEQNCQNYGGYSNPLF 3801
Query: 3174 QCSMQTIKEWQVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCLDVSTALCDGI 2995
QCS QT+KEWQVCDGRWDCADGLDE PEMC SR+ARCFRIG+CDDKKQCLDVSTALCDG
Sbjct: 3802 QCSRQTVKEWQVCDGRWDCADGLDEYPEMCKSRQARCFRIGFCDDKKQCLDVSTALCDGF 3861
Query: 2994 RDCFDGSDENPIHCKDMCKGKYRCTNGRCIDVSARXXXXXXXXXXXXXXXXGAECHHFGV 2815
+DC DGSDE+P HCKDMCKG +RCTNGRC+D SAR G +CHHFG
Sbjct: 3862 KDCSDGSDESPAHCKDMCKGMFRCTNGRCLDESARCDGRDDCGDGSDEDTCGLQCHHFGT 3921
Query: 2814 CAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQVSV 2635
C QKCWMA+N TARCHC GY ++ N+CEPL+K E+F++NG RLHLM E ++
Sbjct: 3922 CPQKCWMAYNSTARCHCDVGYTKS-TKYNDCEPLTKFTEIFLSNGKRLHLMVAEETR--- 3977
Query: 2634 LRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGL-IGSWGE--EE 2464
LR VFN +MN+I GGIDFGYD+++TTLMY+VGIG +RVDIR+KKWS+ WGE +E
Sbjct: 3978 LRTVFNERMNIISGGIDFGYDMYKTTLMYSVGIGKNRVDIRTKKWSESKPSDEWGEKNDE 4037
Query: 2463 STAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLA 2284
STAGLI +DFMHNNVY TES G+LF Q NIYVAK+KDT+TRTLIVNSTG+I SL+
Sbjct: 4038 STAGLIAHDFMHNNVYLTESGSYIPGILFHTQENIYVAKSKDTNTRTLIVNSTGSITSLS 4097
Query: 2283 VDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSN 2104
VDPI+RLIFWTT APVPRILSA+LDG PIAQ FKTGSQPHKAL+ERNIF+P S++LD N
Sbjct: 4098 VDPIQRLIFWTTGAPVPRILSAHLDGTPIAQLFKTGSQPHKALIERNIFDPKSLILDSPN 4157
Query: 2103 ERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITRQGSIHRMHKF 1924
+RLYWID KRT+ETVS+DGRDRRTVRKFELGD+PV+MD++GGYIYL+T QG+IH+MHKF
Sbjct: 4158 KRLYWIDGFKRTVETVSYDGRDRRTVRKFELGDSPVSMDIIGGYIYLVTLQGNIHKMHKF 4217
Query: 1923 TGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDKNGI 1744
+GKTNKY Q+IR+V+PRI++ +AHP+KHTVSHITHQKNPCQSDYCPS TVC+P +D NG+
Sbjct: 4218 SGKTNKYPQRIRDVAPRIRLLIAHPSKHTVSHITHQKNPCQSDYCPSETVCIPKEDTNGV 4277
Query: 1743 LIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCSPQKTCVCPPGFYGRQ 1564
LIPKCLCG GRFFE STKKC+ + + +QEASQCGDYFCYNNA CS QK C+CPPGFYGRQ
Sbjct: 4278 LIPKCLCGAGRFFEESTKKCLPVHDMNQEASQCGDYFCYNNAACSAQKKCICPPGFYGRQ 4337
Query: 1563 CEINECSETCWNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPC 1384
CEINECSE CWNGETCA++E G+T N+ CHCP+NYTQ CATNVCEGVCGPRGSCKTVPC
Sbjct: 4338 CEINECSERCWNGETCAIRESGATRNIECHCPANYTQIDCATNVCEGVCGPRGSCKTVPC 4397
Query: 1383 PKDEPHCRSYSFCECDKGWTGPHCRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLT 1204
++EPHCRSYS+CECDKGW+GPHCRHK DAK+CYGHCFSGG C G+ P NL+C C G
Sbjct: 4398 TREEPHCRSYSYCECDKGWSGPHCRHKIDAKICYGHCFSGGECQGDQPSNLKCQCRPGFN 4457
Query: 1203 GNRCQNCVGHECLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDI 1024
GNRCQNC ECLNGGFCSY SNR++ HCICPSG+TGD+CEEYLCKDAC +G KC YD
Sbjct: 4458 GNRCQNCKDRECLNGGFCSYFGSNRTMSHCICPSGYTGDNCEEYLCKDACSYGEKCVYDF 4517
Query: 1023 TKPMDPITCSCEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRC 844
T + PI+C CE+NAAA N DCSPIC KQPNWCHNGG+CLD PG PGKCKCLPRF GPRC
Sbjct: 4518 TNHLQPISCFCEKNAAAPNADCSPICHKQPNWCHNGGKCLDMPGSPGKCKCLPRFTGPRC 4577
Query: 843 DVPVQCDDYCTNNSKCTITNGTHFECDCKPGFKGLRCEQETKCSECSNEAKCIKKPSGTV 664
DVPV CDDYCTNNSKC TNGTHFEC+CKPGFKGLRCEQET CSEC N AKCIK+PS TV
Sbjct: 4578 DVPVLCDDYCTNNSKCIETNGTHFECECKPGFKGLRCEQETLCSECQNGAKCIKQPSRTV 4637
Query: 663 ICQCPQGLGGEYCEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSSN 484
+CQCP+GLGG+YCE+ITA SC+QL+C+NGGYCL+PD +R P C+C PGF+G+LC S+
Sbjct: 4638 LCQCPEGLGGKYCEEITAVSCNQLKCQNGGYCLEPDSDVDRNRPQCVCRPGFQGILCGSH 4697
Query: 483 ACENFCLHDGNCTLDEYFEPQCECYQAFIGDRCQYRIHQHAVIFSDDDSGWIKSFXXXXX 304
+C+NFC HDG C+L+E FEPQCECY+AF GDRCQYR+ D W + F
Sbjct: 4698 SCDNFCHHDGKCSLNEEFEPQCECYKAFTGDRCQYRVSHLTPPSEADSLSWTRFFVILII 4757
Query: 303 XXXXXXXXXXIFANRSNRFAVFRQFRHNPLQNQGAPVDQFSNPAYLIDEGGIELVTQNTS 124
I ANRSNRFAVFRQFRHNPLQN AP DQFSNPAYLIDEGGIEL+TQNTS
Sbjct: 4758 VILTIVLLIGIVANRSNRFAVFRQFRHNPLQNHEAPADQFSNPAYLIDEGGIELITQNTS 4817
Query: 123 LVSSHDRGSFNNPVFEQEMVPIYNDTVENHELLPNNRSSN 4
LVSSH+RGSFNNP FEQEMVPIYNDTVENHELLP NRSSN
Sbjct: 4818 LVSSHERGSFNNPAFEQEMVPIYNDTVENHELLP-NRSSN 4856
Score = 330 bits (845), Expect = 4e-88
Identities = 250/865 (28%), Positives = 358/865 (40%), Gaps = 104/865 (12%)
Frame = -1
Query: 6423 ENEFRCQSGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIH 6244
+N + C S + C H +GC C CA
Sbjct: 861 KNSLSKSTSPCSTSSSNCEHFCFATSCKGSVGCEPVKCG------------CA------- 901
Query: 6243 PSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDG 6064
DG +G KD E P CD +F CL +R C+PK CDG
Sbjct: 902 -----DGMKLVDNGKCVKDEHWE---------DPNGCDEDREFTCLNSRKCIPKANLCDG 947
Query: 6063 QPDCADGSDEKN---CDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQ--CET 5899
DC DGSDE + C KC +F C+S+ CIPLE CDG+ DC DG DE + C+T
Sbjct: 948 DDDCGDGSDEDSNGICKDFKCVGNKFQCDSTT-CIPLEFLCDGKSDCNDGTDELETMCKT 1006
Query: 5898 ECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCAD 5719
D + FRC+N +CI + RC+G DC + GSDE DC + RC
Sbjct: 1007 VPDVRCSVGQFRCSNTKCIDKSKRCNGIQDCEN-----GSDEEDCPRSKLCTPTEFRCGT 1061
Query: 5718 ETCVVACELTAVLCDGIQDCSDGFDEKNCAS-------------------LDR--QC--- 5611
C+ ++ CDG C DG DEK+C LD QC
Sbjct: 1062 GLCIKQSQV----CDGKMQCLDGLDEKHCEENNSCIKGRQFRCANKQSTCLDMIFQCDGV 1117
Query: 5610 -----------------------KPNEWMCDSGQCIDSGRLCDASVDCVDGSDEWVEICS 5500
K N++MC G+C+ S +LCD DC+ G DE S
Sbjct: 1118 PDCEDESDESPEFCKGNTSSSCAKMNQFMCADGKCLRSFQLCDGFPDCLTGEDEKECPPS 1177
Query: 5499 L-SEPPRRGCPSGWSCL---------------------------------------LTNG 5440
+ + C +G C+ +G
Sbjct: 1178 MCNSATHLSCANGNKCVSKELECDGVDDCGDKSDESHCDDIRMEAALLRCIPPMYKCQSG 1237
Query: 5439 TIGCLQEQQLCDGRRDCMSGIDEQ--CDNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDD 5266
C+ ++QLCDG+ DC SG DE C C+ST C T C+ CSC D
Sbjct: 1238 RFQCISDKQLCDGKNDCPSGDDEGMWCSFL---CNSTEIGCSHT--CRATPSGPICSCPD 1292
Query: 5265 GYHLSPYDKKTCLRSPSCPKANCSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEA 5086
Y L D TC + C CS C+ + H C+C GY L ++ CR D
Sbjct: 1293 EYFLEK-DGVTCAKKDPCRFGQCSQHCMSQGS-RHFCYCEDGYKLLNDRISCRTVDPKTE 1350
Query: 5085 EILMVYGHRLKLFTIDGHAKATLLSNLTNGVALDYDVKSD---LVYWTDVAHDGNKAGIT 4915
++ H +++ L+S+LTN +ALD+ ++ +VYWTD++ D +G+
Sbjct: 1351 FMIYSNRHEIRMIQATSPGSIPLISSLTNAIALDFKYLNNGSLIVYWTDLSSDKIYSGL- 1409
Query: 4914 SMSNQPNTY-RVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGT 4738
M + Y R I S +GIAVDW+ NIY+ D + D I V G R +
Sbjct: 1410 -MDQRTIMYSRTIVSYGVFNAEGIAVDWITGNIYWIDSHLDTIQVLSEDGT-KRATVVNE 1467
Query: 4737 PLNDPRAIVLDPLQALVFWTDW-GASAHIGRMNMDGSNEQVILQDRTIR---WPNALAVD 4570
+ + R++ +D + L+FWTDW A+ I R + G N + + + WPN +A+D
Sbjct: 1468 NMGNARSLAIDVEEGLMFWTDWEEANPRIERCTLAGKNRATVWKISNVAQAGWPNGIALD 1527
Query: 4569 APAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVR--HIFALAVFEDYVYWSDWHNHTIE 4396
+R+Y+ DA D I + YDG +VLR R H F + V+ D VY+SDW +TI
Sbjct: 1528 TITKRVYWVDAKSDSIHTITYDGRDHVLVLRDPERLGHCFGIDVYGDNVYFSDWRTNTIS 1587
Query: 4395 RVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDNLCIPANTP 4216
V+K G +++ +P KIVH S Q + ++ C +C+ +C
Sbjct: 1588 TVNKF-GKGEVTIVERVATQPFSLKIVHRSKQK----RQLKNMC-DGFKCNGIC------ 1635
Query: 4215 DLTTSSDNFTCMCAQGFRSEGRSCV 4141
L + +C C + CV
Sbjct: 1636 -LNDGRNKASCQCTNIQTTTDDGCV 1659
Score = 318 bits (815), Expect = 1e-84
Identities = 384/1655 (23%), Positives = 622/1655 (37%), Gaps = 154/1655 (9%)
Frame = -1
Query: 4914 SMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRF-------NR 4756
S N T V+ + + + +A D + R +YY N I D+ +
Sbjct: 2375 SAVNFDGTGCVVIAEDVRVVPSMAYDEVNRELYYVSANPAGIWRIDVADNNLENYPTEPK 2434
Query: 4755 ILLKGTPLNDPRAIVLDPLQALVFWTDWGASAH-IGRMNMDGSNEQVILQDRTIRWPNAL 4579
++L T + PR + +DP + L+F+T+ + I R G + ILQ+ + L
Sbjct: 2435 LVLLLTNRDRPRHLAIDPCRMLLFFTNNAITGSVIERAYFSGYKREQILQE-DLHDLRGL 2493
Query: 4578 AVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVR---HIFALAVFEDYVYWSDWHN 4408
A+D ++LYF D+ I+ C+ DG R +V+ S H F L ++E+ + ++DW
Sbjct: 2494 AIDLETEKLYFSDSKDFRISRCDLDGCNREVVISNSDNPSIHPFELEIYENEIIFTDWVK 2553
Query: 4407 HTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPC-SQPARCDNLCI 4231
+ ++KI+G +++ + + P+G +V S + ++PC +C + C
Sbjct: 2554 RAVSGINKISGVEHRLMNRATEV-PVGLVVVDVSKEF-----CTKNPCYENELKCGDYC- 2606
Query: 4230 PANTPDLTTSSDNFTCMC--AQGFRSEGRSCVSE-----CKPNDFVCTKTYKCI--SSWW 4078
+ TC C + ++ ++C + C N+F C + KCI
Sbjct: 2607 ------RLMADGQATCACNGERRLSADNKTCTGDVDEKKCAENEFKCLHSDKCIPYEDTC 2660
Query: 4077 RXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSG 3898
Y VC P G F CG C+ SK+C+ DC
Sbjct: 2661 DQYNDCPMFDDEDAKYCSSRVCRP-----GYFDCG------NGLCISESKVCNRFNDCIN 2709
Query: 3897 GDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCKP---- 3730
DE N C++++FKC D CIP C+ +DC+D SDE+ C +C
Sbjct: 2710 FHDE-----NNCTCSKSEFKC-DSGNCIPGEDRCNHVQDCNDASDEIGCPYRNCSSLVEF 2763
Query: 3729 DFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSC----FGIGEC-------THEQFQ 3583
N + S+CI + CDG +DC +G DE D F G + QF
Sbjct: 2764 GMSDLINCASTSQCIHPSWKCDGTNDCYDGSDELDCLVEFDFNKGSVSPPRSCDSATQFP 2823
Query: 3582 CTSGK-CIPKRRQCDGTLDCRDGSDEKGCKKECA----IVCDNS--CVHADDLCDGKKKC 3424
C + + C+P R +CDG DC DGSDE C+++ C+++ C+ + CDG+ C
Sbjct: 2824 CLATRNCMPNRWRCDGQPDCADGSDEANCEQKACNSFEFTCESTKKCIPLEQKCDGRSDC 2883
Query: 3423 NDGSDED--EEACVIK---QLLEKENRKCGGFA--CDGIVDCEDGSDEKGCPDLEC---- 3277
+G DE+ + C K N +C A CDG DC D + G +++C
Sbjct: 2884 PNGEDENSCDTECDSKNGNSTFRCTNHRCIPMAWRCDGTDDCLDNAKSLGSDEMDCAPGK 2943
Query: 3276 ---HLASN------------KSLICDGTIDCSSGKDENNC---HNNGESNFFQC-SMQTI 3154
H+ S +++CDG DC+ G DE NC + N + C S Q I
Sbjct: 2944 TSFHVPSRCTDETCVVACELTAVLCDGIKDCNDGFDEENCASLDRQCKLNEWMCDSGQCI 3003
Query: 3153 KEWQVCDGRWDCADGLDESPEMCA---SRKARCFRIGYCDDKK---QCLDVSTALCDGIR 2992
+CD DC DG DE E+C+ K C C K CL LCDG +
Sbjct: 3004 NSAHLCDSSVDCIDGSDEWVEICSLSEPPKRGCPNGWSCVLKNGTIGCLQ-EHQLCDGRK 3062
Query: 2991 DCFDGSDE-------NPIHCKDMCKGKYRCTNGRCIDVSARXXXXXXXXXXXXXXXXGAE 2833
DC G DE N ++ C+ + C + +
Sbjct: 3063 DCMSGIDEQCDLPQGNCSSARNSCEQPWNCKRNAGFETCSCDEGFHLSPYDKRTCLRSPS 3122
Query: 2832 CHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLE 2653
C C+ C + +C CAPG+ + N + + E+ + +G+RL L +++
Sbjct: 3123 CPKAN-CSHFCIDRRDVGHQCFCAPGFILSDNQRDCRRNDTIEPEILMVSGHRLKLFTID 3181
Query: 2652 NSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSR-----VDIRSKKWSDGL 2488
+ L ++ + G+ YDV ++ L+Y + NS + ++ ++ +
Sbjct: 3182 GHAKATL-------LSNLTNGVALDYDV-KSDLVYWTDVTNSGNKAGITSMSNQPYTYRI 3233
Query: 2487 IGSWGEEESTAGL--ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIV 2314
I S T G+ I D++ ++Y+T+ + I V + R L+
Sbjct: 3234 INSL----PTKGIDGIAVDWLGRHIYYTDRNHD----------AIAVCDMRGRFNRILLK 3279
Query: 2313 NS-TGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIF 2137
+ ++ +DPI+ L+FWT I N+D GS L +R I
Sbjct: 3280 GTPLNDPRAIVLDPIQALLFWTDWGASAHIGRMNMD----------GSNEMIILEDRTIR 3329
Query: 2136 EPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT 1957
P ++ +D +RLY+ D + I + ++DG RR V + + + V YIY
Sbjct: 3330 WPNALAVDAPAQRLYFGDAHRDYIASCNYDGTKRRMVLRNSVRHI-FALAVFEDYIYWSD 3388
Query: 1956 -RQGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSN 1780
+I R+HK TG K + + ++ P + +V HP+ + + K+PC S +
Sbjct: 3389 WHNHTIERVHKITGDNRKVLIQDKQYRP-MGFKVVHPSFQNMGSMKTAKHPC-SQPARCD 3446
Query: 1779 TVCVPDQDKNGILI----------PKCL--CGPGRFFEVSTKKCMQLREKDQEASQCGD- 1639
+C+P C+ C P F T KC+ + CGD
Sbjct: 3447 NLCIPASSPEAFTCMCAQGFRSDGRSCVSECKPNDFVCTKTYKCIASWWRCDGQDDCGDG 3506
Query: 1638 ----YFCYNNAGCSPQKTC-----VCPPGFYGRQCEINECSETCWNGETCAVQEFGSTTN 1486
YF G PQ C +CP + S+ C + C E T
Sbjct: 3507 EDEGYFL---KGVCPQFPCDPGQFLCPKSPRNTTAQCLYASKLCDGVKDCLEGEDEEKT- 3562
Query: 1485 VVCHCPSNYTQSSCATNVCEGVCGPRGSC--KTVPCPKDEPHCRSYSFCECDKGWTGPHC 1312
C C + + CG + C T C K++ +CD G C
Sbjct: 3563 -FCE------HFECTES--QFKCGDKKKCIPLTSVCDKEK---------DCDDGSDERSC 3604
Query: 1311 RHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQNCVGHECLNGGFCSYANSN 1132
+ K C F AC E T ++ C+ E G N
Sbjct: 3605 ----EIKSCKPDFF---ACVNE-------------TTSQISKCIPKEFYCDGEDDCPNGQ 3644
Query: 1131 RSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCSCEQNAAAHNTDCSP 952
C G E++ C KC K I C + +C+
Sbjct: 3645 DEPDTCF---GIGECTHEQFQCA-----SGKCIPKRRKCDGTIDCRDGSDEKGCKKECAI 3696
Query: 951 ICQKQ----PNWCHNGGRCLDTPGYPGKCKCLPRF---------AGPRCDVPVQCDDYCT 811
+C + C +C + + + G +CD + C+D
Sbjct: 3697 VCDNECVPVEELCDGKRKCTHGTDEEEEACAIKKLMEKPVLRTCGGFKCDGIIDCEDGAD 3756
Query: 810 NNS----KCTITNGTHFEC----DCKPGFKGLRCEQ----ETKCSECSNEAKCIKKPSGT 667
+C ++N C DC+ G C+ +CS + +K+
Sbjct: 3757 EKGCPDLECHLSNNASLICDGKVDCESGKDEQNCQNYGGYSNPLFQCSRQT--VKE---W 3811
Query: 666 VIC----QCPQGLGGEYCEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGL 499
+C C GL EY E + Q C G+C D T LC GFK
Sbjct: 3812 QVCDGRWDCADGL-DEYPEMCKS---RQARCFRIGFC--DDKKQCLDVSTALCD-GFKD- 3863
Query: 498 LCSSNA------CENFCLHDGNCTLDEYFEPQCEC 412
CS + C++ C CT + C
Sbjct: 3864 -CSDGSDESPAHCKDMCKGMFRCTNGRCLDESARC 3897
Score = 296 bits (759), Expect = 3e-78
Identities = 308/1216 (25%), Positives = 493/1216 (40%), Gaps = 65/1216 (5%)
Frame = -1
Query: 5214 CPKANCSHFCIDRRDVGHQCFCAPGYILSENQ-KDCRRNDTIEAEILMVYGHRLKLFTID 5038
C A+C CI + C C G I EN+ ++ +N+ + EIL++ R +
Sbjct: 548 CKAASCDDICIGHIEKTFSCLCRDGLIQKENKCQEIDQNELKDKEILILAQLRPARVKVL 607
Query: 5037 GHAKATLLSNL--------TNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRV 4882
G K ++ A+ +D K + D+ + + M T+
Sbjct: 608 GFNKDYQTEDIGIPDILAAKRPSAITFDPKGKRILMYDLKR--HSLVVQKMDQSNTTFHG 665
Query: 4881 INSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRG-RFNRILLKGTPLNDPRAIVLD 4705
+ + +G+A D+ N+Y TD+ I V + +I+++G +++PRAI +
Sbjct: 666 LTGI--MNCEGMAYDYTSDNLYMTDQKRKLITVQRLSNLSVQKIIVRGN-MSNPRAIAVH 722
Query: 4704 PLQALVFWTDWGAS--------AHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLY 4549
++ +FW W A I R +DGS + ++ ++ W N L +D LY
Sbjct: 723 VAKSYLFWGSWSEDRQNDATTPAMIERSKLDGSERKTLVSKNSM-WINGLTLDLKNDFLY 781
Query: 4548 FGDAHRDYIASCNYDGSKRRMVLRG--SVRHIFALAVFEDYVYWSDWHNHTIERVHKITG 4375
+ DA+R+ I ++G+ R ++++G + H + LA F+++++++++ ++RV+
Sbjct: 782 WCDAYRNVIERIRWNGADREVIIQGVDKISHPYGLAFFDNHIFFTEFKRGAVKRVN---- 837
Query: 4374 TNRKVLIQD-KQYRPMGFKIVHPSLQSMGSLKTARHPCS-QPARCDNLCIPANTPDLTTS 4201
N +Q+ QY F++ SL + PCS + C++ C A + +
Sbjct: 838 VNFPDQVQEIFQYSATVFELA----VFKNSLSKSTSPCSTSSSNCEHFCF-ATSCKGSVG 892
Query: 4200 SDNFTCMCAQGFR-SEGRSCVSE--------C-KPNDFVCTKTYKCISSWWRXXXXXXXX 4051
+ C CA G + + CV + C + +F C + KCI
Sbjct: 893 CEPVKCGCADGMKLVDNGKCVKDEHWEDPNGCDEDREFTCLNSRKCIPK--ANLCDGDDD 950
Query: 4050 XXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFC 3871
G+C F C+ +F C T C+ LCDG DC+ G DE C
Sbjct: 951 CGDGSDEDSNGICKDFKCVGNKFQCDSTT------CIPLEFLCDGKSDCNDGTDELETMC 1004
Query: 3870 E---NFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITS-CKPDFFACFNGT 3703
+ + C+ QF+C + KCI + C+ +DC++GSDE +C + C P F C G
Sbjct: 1005 KTVPDVRCSVGQFRCSN-TKCIDKSKRCNGIQDCENGSDEEDCPRSKLCTPTEFRCGTGL 1063
Query: 3702 AISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTH-EQFQCTS--GKCIPKRRQCDGTL 3532
CI + CDG+ C +G DE C C QF+C + C+ QCDG
Sbjct: 1064 ----CIKQSQVCDGKMQCLDGLDE-KHCEENNSCIKGRQFRCANKQSTCLDMIFQCDGVP 1118
Query: 3531 DCRDGSDE----------KGCKKECAIVC-DNSCVHADDLCDGKKKCNDGSDEDE---EA 3394
DC D SDE C K +C D C+ + LCDG C G DE E
Sbjct: 1119 DCEDESDESPEFCKGNTSSSCAKMNQFMCADGKCLRSFQLCDGFPDCLTGEDEKECPPSM 1178
Query: 3393 CVIKQLLEKEN-RKCGG--FACDGIVDCEDGSDEKGCPDLECHLASNKSLICDGTIDCSS 3223
C L N KC CDG+ DC D SDE C D+ A + + C S
Sbjct: 1179 CNSATHLSCANGNKCVSKELECDGVDDCGDKSDESHCDDIRMEAALLRCI--PPMYKCQS 1236
Query: 3222 GKDENNCHNNGESNFFQCSMQTIKEWQVCDGRWDCADGLDESPEMCASRKARCFRIGYCD 3043
G+ FQC I + Q+CDG+ DC G DE M S IG C
Sbjct: 1237 GR-------------FQC----ISDKQLCDGKNDCPSGDDEG--MWCSFLCNSTEIG-CS 1276
Query: 3042 DKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKGKYRCTNGRCIDVSARXXXXXXXXX 2863
+ S +C + F D KD C+
Sbjct: 1277 HTCRATP-SGPICSCPDEYFLEKDGVTCAKKDPCR------------------------- 1310
Query: 2862 XXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITN 2683
FG C+Q C M+ C+C GY + ND C + E I +
Sbjct: 1311 -------------FGQCSQHC-MSQGSRHFCYCEDGY-KLLNDRISCRTVDPKTEFMIYS 1355
Query: 2682 GNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRV-----D 2518
M S S+ P+ + N I +DF Y + ++Y + + ++ D
Sbjct: 1356 NRHEIRMIQATSPGSI--PLISSLTNAI--ALDFKYLNNGSLIVYWTDLSSDKIYSGLMD 1411
Query: 2517 IRSKKWSDGLIGSWGEEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKD 2338
R+ +S ++ S+G + I D++ N+Y+ +S VL ++D
Sbjct: 1412 QRTIMYSRTIV-SYGVFNAEG--IAVDWITGNIYWIDSHLDTIQVL-----------SED 1457
Query: 2337 TSTRTLIVN-STGTINSLAVDPIKRLIFWTT-SAPVPRILSANLDGKPIAQPFKTGSQPH 2164
+ R +VN + G SLA+D + L+FWT PRI L GK A +K +
Sbjct: 1458 GTKRATVVNENMGNARSLAIDVEEGLMFWTDWEEANPRIERCTLAGKNRATVWKISNVAQ 1517
Query: 2163 KALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTV-RKFELGDTPVTMD 1987
P + LD +R+YW+D +I T+++DGRD V R E +D
Sbjct: 1518 AGW-------PNGIALDTITKRVYWVDAKSDSIHTITYDGRDHVLVLRDPERLGHCFGID 1570
Query: 1986 VLGGYIYLIT-RQGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKN 1810
V G +Y R +I ++KF GK + + R + +++ H +K KN
Sbjct: 1571 VYGDNVYFSDWRTNTISTVNKF-GKGEVTIVE-RVATQPFSLKIVHRSKQK----RQLKN 1624
Query: 1809 PCQSDYCPSNTVCVPD 1762
C C N +C+ D
Sbjct: 1625 MCDGFKC--NGICLND 1638
Score = 124 bits (312), Expect = 2e-26
Identities = 107/353 (30%), Positives = 143/353 (40%), Gaps = 30/353 (8%)
Frame = -1
Query: 6069 DGQPDCADG------SDEKNC----DAKKCTSFEFSCESSKKCIPLEQKCDGRRDCP--D 5926
DGQ CA +D K C D KKC EF C S KCIP E CD DCP D
Sbjct: 2611 DGQATCACNGERRLSADNKTCTGDVDEKKCAENEFKCLHSDKCIPYEDTCDQYNDCPMFD 2670
Query: 5925 GEDEHQCETECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTS 5746
ED C + G F C N CI + C+ +DC++ DE +C ++
Sbjct: 2671 DEDAKYCSSRVCRPG---YFDCGNGLCISESKVCNRFNDCIN-----FHDENNCTCSKSE 2722
Query: 5745 FHVPSRCADETCVVACELTAVLCDGIQDCSDGFDE-----KNCASLDRQCKPNEWMCDS- 5584
F +C C+ + C+ +QDC+D DE +NC+SL + C S
Sbjct: 2723 F----KCDSGNCIPGED----RCNHVQDCNDASDEIGCPYRNCSSLVEFGMSDLINCAST 2774
Query: 5583 GQCIDSGRLCDASVDCVDGSDEW-----VEICSLSEPPRRGCPSG--WSCLLTNGTIGCL 5425
QCI CD + DC DGSDE + S P R C S + CL T C+
Sbjct: 2775 SQCIHPSWKCDGTNDCYDGSDELDCLVEFDFNKGSVSPPRSCDSATQFPCLATR---NCM 2831
Query: 5424 QEQQLCDGRRDCMSGIDE-QCDNPQGNCSSTRNSCDQTWNC----QRHAGFESCSCDDGY 5260
+ CDG+ DC G DE C+ Q C+S +C+ T C Q+ G C +
Sbjct: 2832 PNRWRCDGQPDCADGSDEANCE--QKACNSFEFTCESTKKCIPLEQKCDGRSDCPNGE-- 2887
Query: 5259 HLSPYDKKTCLRSPSCPKANCSHFCIDRRDVGHQCFCAPGYILSENQKDCRRN 5101
D+ +C N + C + R C P + DC N
Sbjct: 2888 -----DENSCDTECDSKNGNSTFRCTNHR-------CIPMAWRCDGTDDCLDN 2928
Score = 92.0 bits (227), Expect = 2e-16
Identities = 56/157 (35%), Positives = 75/157 (47%), Gaps = 18/157 (11%)
Frame = -1
Query: 3744 TSCKPDFFACFNGTAIS-KCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGK 3568
+SC P C +GT KC P++++CDG DC + DEP +C C +F C +GK
Sbjct: 33 SSCVPPMRECDSGTPSGPKCYPEQWFCDGYPDCRDNSDEPPTCKRA--CLENEFVCKTGK 90
Query: 3567 CIPKRRQCDGTLDC-------RDGSDEK--------GCK-KECAIVCDNSCVHADDLCDG 3436
C+P+ CDG LDC +D SDE C+ E A CV CDG
Sbjct: 91 CLPRGYLCDGQLDCGRFPDGLQDRSDESRELCNQPLNCEHNEYACAASAQCVPLFKFCDG 150
Query: 3435 KKKCNDGSDEDEEACVIKQLLEKENRKCG-GFACDGI 3328
K C+DGSD E C +K + + + G DGI
Sbjct: 151 KLDCSDGSD---EVCRVKNISTANDCEYGAAITIDGI 184
Score = 89.7 bits (221), Expect = 8e-16
Identities = 120/552 (21%), Positives = 206/552 (36%), Gaps = 40/552 (7%)
Frame = -1
Query: 5679 CDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASVDC-------VDGSD 5521
CDG DC D DE + R C NE++C +G+C+ G LCD +DC D SD
Sbjct: 59 CDGYPDCRDNSDEP--PTCKRACLENEFVCKTGKCLPRGYLCDGQLDCGRFPDGLQDRSD 116
Query: 5520 EWVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCS 5341
E E+C+ P + ++C + C+ + CDG+ DC G DE C +
Sbjct: 117 ESRELCN---QPLNCEHNEYACA---ASAQCVPLFKFCDGKLDCSDGSDEVC---RVKNI 167
Query: 5340 STRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDK----KTCLRSPSCPKANCSHFCIDRR 5173
ST N C+ + C C L+ K C R + CS C D +
Sbjct: 168 STANDCE--YGAAITIDGIKCYCPKNKFLNEKGKCEFVNQCDRLKNGLPPACSQGCTDNK 225
Query: 5172 DVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAK---ATLLSNLT 5002
+ CFC + N C + + + + K++TI ++L L
Sbjct: 226 NGTFSCFCFDPRLTVANGTHCVAEKDVSIPSVAIL-TKQKIYTIQNGTMSNYSSLPRPLG 284
Query: 5001 NGVAL-------DYDVKSDLVYWTDVAHDGNKAGITS---MSNQPNTYRVINSLPTKGID 4852
AL D+ + A N++ IT ++P T I
Sbjct: 285 KPGALTLVFQHPDFPEAKVPILCLSEAPTSNQSYITCGNVEGSEPVTKSYAVDFDISAIH 344
Query: 4851 GIAVDWLGRNIYYTDRN-------HDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQA 4693
I D G N +TD + HD++ + + + + D +
Sbjct: 345 MIRFDNFGNNWIFTDASYYIFICKHDSVKISKCH------TFAAGAMGTLQDVQYDGVNG 398
Query: 4692 LVFWTDWG-ASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIAS 4516
F TD I R+++ S E+ L + I P ALA+D + LY+ D+ + I +
Sbjct: 399 QFFVTDSDYFQQGIWRIDV-ASGERNRLTTQPITSP-ALAIDPFTKTLYYVDSSANSIKA 456
Query: 4515 CNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYR 4336
+Y+ + R+V+ G + + + ++ ++ + + + + VL ++
Sbjct: 457 IDYNSNFSRIVVSGRIAKEVTQLDYAEGKLFATLRDNRVFVANALESDSEAVLKTWQEIT 516
Query: 4335 PMG--------FKIVHPSLQSMGSLKTARHPCSQPARCDNLCIPANTPDLTTSSDNFTCM 4180
P ++ H + R+ C + A CD++CI F+C+
Sbjct: 517 PPSNGGPNKVIMEVFHFRRNANAWKNKGRNIC-KAASCDDICI-------GHIEKTFSCL 568
Query: 4179 CAQGFRSEGRSC 4144
C G + C
Sbjct: 569 CRDGLIQKENKC 580
Score = 80.5 bits (197), Expect = 5e-13
Identities = 65/217 (29%), Positives = 93/217 (41%), Gaps = 14/217 (6%)
Frame = -1
Query: 3822 KCIPLTSVCDKEKDCDDGSDELNCEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDC-- 3649
KC P CD DC D SDE +C + F C G KC+P+ + CDG+ DC
Sbjct: 51 KCYPEQWFCDGYPDCRDNSDEPPTCKRACLENEFVCKTG----KCLPRGYLCDGQLDCGR 106
Query: 3648 -PEG-QDEPDS----CFGIGECTHEQFQC-TSGKCIPKRRQCDGTLDCRDGSDEKGCKKE 3490
P+G QD D C C H ++ C S +C+P + CDG LDC DGSDE C+ +
Sbjct: 107 FPDGLQDRSDESRELCNQPLNCEHNEYACAASAQCVPLFKFCDGKLDCSDGSDEV-CRVK 165
Query: 3489 CAIVCDNSCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKENRKCGGFACDGIVDCEDG 3310
I N C + + KC C + L ++ + CD + +
Sbjct: 166 -NISTANDCEYGAAITIDGIKC---------YCPKNKFLNEKGKCEFVNQCDRLKNGLPP 215
Query: 3309 SDEKGCPD-----LECHLASNKSLICDGTIDCSSGKD 3214
+ +GC D C + + +GT C + KD
Sbjct: 216 ACSQGCTDNKNGTFSCFCFDPRLTVANGT-HCVAEKD 251
Score = 79.0 bits (193), Expect = 1e-12
Identities = 42/124 (33%), Positives = 64/124 (50%), Gaps = 10/124 (8%)
Frame = -1
Query: 6255 QCIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHW 6076
+C W CDG DC D SDE + R+C + +F C T C+P+ +
Sbjct: 51 KCYPEQWFCDGYPDCRDNSDEPP------------TCKRAC-LENEFVC-KTGKCLPRGY 96
Query: 6075 QCDGQPDCA---DGSDEKNCDAKK-------CTSFEFSCESSKKCIPLEQKCDGRRDCPD 5926
CDGQ DC DG +++ ++++ C E++C +S +C+PL + CDG+ DC D
Sbjct: 97 LCDGQLDCGRFPDGLQDRSDESRELCNQPLNCEHNEYACAASAQCVPLFKFCDGKLDCSD 156
Query: 5925 GEDE 5914
G DE
Sbjct: 157 GSDE 160
Score = 73.6 bits (179), Expect = 6e-11
Identities = 65/242 (26%), Positives = 93/242 (37%), Gaps = 30/242 (12%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGL-----CIPEQKVCNRINDCANFADES-NC--TCNENE 6415
D K +T C P C +G C PEQ C+ DC + +DE C C ENE
Sbjct: 24 DSSLKKANTSSCVPPMRECDSGTPSGPKCYPEQWFCDGYPDCRDNSDEPPTCKRACLENE 83
Query: 6414 FRCQSGACIPSKARCNHMQDC----------NDASDEIGCPFRNCSALNEFGMTGLINCA 6265
F C++G C+P C+ DC +D S E+ NC NE+ CA
Sbjct: 84 FVCKTGKCLPRGYLCDGQLDCGRFPDGLQDRSDESRELCNQPLNCEH-NEYA------CA 136
Query: 6264 TTSQCIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMP 6085
++QC+ CDG DC DGSDE C V+ ++S C+ + P
Sbjct: 137 ASAQCVPLFKFCDGKLDCSDGSDEV-CRVK------NISTANDCEYGAAITIDGIKCYCP 189
Query: 6084 KHW------------QCDGQPDCADGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGR 5941
K+ QCD + + + C K +F C + + C
Sbjct: 190 KNKFLNEKGKCEFVNQCDRLKNGLPPACSQGCTDNKNGTFSCFCFDPRLTVANGTHCVAE 249
Query: 5940 RD 5935
+D
Sbjct: 250 KD 251
Score = 64.7 bits (156), Expect = 3e-08
Identities = 39/116 (33%), Positives = 56/116 (47%), Gaps = 10/116 (8%)
Frame = -1
Query: 3948 QCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDC--- 3778
+C CDG DC DE P C+ C E +F C KC+P +CD + DC
Sbjct: 51 KCYPEQWFCDGYPDCRDNSDEPPT-CKR-ACLENEFVC-KTGKCLPRGYLCDGQLDCGRF 107
Query: 3777 -------DDGSDELNCEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDE 3631
D S EL + +C+ + +AC A ++C+P +CDG+ DC +G DE
Sbjct: 108 PDGLQDRSDESRELCNQPLNCEHNEYAC---AASAQCVPLFKFCDGKLDCSDGSDE 160
Score = 62.4 bits (150), Expect = 1e-07
Identities = 42/141 (29%), Positives = 63/141 (43%), Gaps = 20/141 (14%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANF-------ADESNCTCNE-- 6421
D+ D R C F C G C+P +C+ DC F +DES CN+
Sbjct: 67 DNSDEPPTCKRACLENEFVCKTGKCLPRGYLCDGQLDCGRFPDGLQDRSDESRELCNQPL 126
Query: 6420 ----NEFRCQSGA-CIPSKARCNHMQDCNDASDEIGCPFRNCSALN--EFG----MTGLI 6274
NE+ C + A C+P C+ DC+D SDE+ C +N S N E+G + G+
Sbjct: 127 NCEHNEYACAASAQCVPLFKFCDGKLDCSDGSDEV-CRVKNISTANDCEYGAAITIDGIK 185
Query: 6273 NCATTSQCIHPSWKCDGTNDC 6211
++ ++ KC+ N C
Sbjct: 186 CYCPKNKFLNEKGKCEFVNQC 206
Score = 58.9 bits (141), Expect = 2e-06
Identities = 50/189 (26%), Positives = 70/189 (36%), Gaps = 33/189 (17%)
Frame = -1
Query: 6042 SDEKNCDAKKCTSFEFSCESSK----KCIPLEQKCDGRRDCPDGEDE-HQCETECDSKGG 5878
S K + C C+S KC P + CDG DC D DE C+ C
Sbjct: 25 SSLKKANTSSCVPPMRECDSGTPSGPKCYPEQWFCDGYPDCRDNSDEPPTCKRACLEN-- 82
Query: 5877 NATFRCTNHRCIPMAWRCDGTDDC----------MDNAKSLGSDEVDCAAGRTSFHVPSR 5728
F C +C+P + CDG DC D ++ L + ++C H
Sbjct: 83 --EFVCKTGKCLPRGYLCDGQLDCGRFPDGLQDRSDESRELCNQPLNCE------HNEYA 134
Query: 5727 CADETCVVACELTAVLCDGIQDCSDGFDE----KNCAS--------------LDRQCKPN 5602
CA C CDG DCSDG DE KN ++ + C N
Sbjct: 135 CA---ASAQCVPLFKFCDGKLDCSDGSDEVCRVKNISTANDCEYGAAITIDGIKCYCPKN 191
Query: 5601 EWMCDSGQC 5575
+++ + G+C
Sbjct: 192 KFLNEKGKC 200
Score = 58.5 bits (140), Expect = 2e-06
Identities = 40/130 (30%), Positives = 55/130 (41%), Gaps = 13/130 (10%)
Frame = -1
Query: 3999 CIAGQFVCGRTAQNATAQCLYASKLCDGVKDCS-------GGDDEEPAFCEN-FECTEAQ 3844
C+ +FVC T +CL LCDG DC DE C C +
Sbjct: 79 CLENEFVC------KTGKCLPRGYLCDGQLDCGRFPDGLQDRSDESRELCNQPLNCEHNE 132
Query: 3843 FKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCKPDFFACFNGTAIS----KC-IPK 3679
+ C +C+PL CD + DC DGSDE+ C + + C G AI+ KC PK
Sbjct: 133 YACAASAQCVPLFKFCDGKLDCSDGSDEV-CRVKNIS-TANDCEYGAAITIDGIKCYCPK 190
Query: 3678 EFYCDGEDDC 3649
+ + + C
Sbjct: 191 NKFLNEKGKC 200
Score = 58.2 bits (139), Expect = 3e-06
Identities = 43/132 (32%), Positives = 51/132 (38%), Gaps = 37/132 (28%)
Frame = -1
Query: 3585 QCTSGKCIPKRRQ-----------------CDGTLDCRDGSDE-KGCKKEC---AIVC-D 3472
+ + C+P R+ CDG DCRD SDE CK+ C VC
Sbjct: 29 KANTSSCVPPMRECDSGTPSGPKCYPEQWFCDGYPDCRDNSDEPPTCKRACLENEFVCKT 88
Query: 3471 NSCVHADDLCDGKKKC-------NDGSDEDEEACVIKQLLEKENRKCGGFA--------C 3337
C+ LCDG+ C D SDE E C E C A C
Sbjct: 89 GKCLPRGYLCDGQLDCGRFPDGLQDRSDESRELCNQPLNCEHNEYACAASAQCVPLFKFC 148
Query: 3336 DGIVDCEDGSDE 3301
DG +DC DGSDE
Sbjct: 149 DGKLDCSDGSDE 160
Score = 52.4 bits (124), Expect = 1e-04
Identities = 39/104 (37%), Positives = 48/104 (45%), Gaps = 10/104 (9%)
Frame = -1
Query: 3249 CDGTIDCSSGKDEN-NCHNNGESNFFQCSM-QTIKEWQVCDGRWDCA---DGL----DES 3097
CDG DC DE C N F C + + +CDG+ DC DGL DES
Sbjct: 59 CDGYPDCRDNSDEPPTCKRACLENEFVCKTGKCLPRGYLCDGQLDCGRFPDGLQDRSDES 118
Query: 3096 PEMCASRKARCFRIGY-CDDKKQCLDVSTALCDGIRDCFDGSDE 2968
E+C ++ C Y C QC+ + CDG DC DGSDE
Sbjct: 119 RELC-NQPLNCEHNEYACAASAQCVPLFK-FCDGKLDCSDGSDE 160
Score = 52.4 bits (124), Expect = 1e-04
Identities = 53/203 (26%), Positives = 75/203 (36%), Gaps = 18/203 (8%)
Frame = -1
Query: 5724 ADETCVVACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMC-DSGQCIDSGRLCDA 5548
AD AC L + C+ DEK CA NE+ C S +CI CD
Sbjct: 2610 ADGQATCACNGERRLSADNKTCTGDVDEKKCAE-------NEFKCLHSDKCIPYEDTCDQ 2662
Query: 5547 SVDCVDGSDEWVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDE- 5371
DC DE + CS R C G+ G C+ E ++C+ DC++ DE
Sbjct: 2663 YNDCPMFDDEDAKYCS-----SRVCRPGY---FDCGNGLCISESKVCNRFNDCINFHDEN 2714
Query: 5370 ---------QCDNPQGNCSSTRNSCDQTWNCQRHAGFESC---SCDDGYHLSPYDKKTCL 5227
+CD+ GNC + C+ +C + C +C D C
Sbjct: 2715 NCTCSKSEFKCDS--GNCIPGEDRCNHVQDCNDASDEIGCPYRNCSSLVEFGMSDLINCA 2772
Query: 5226 RSPSC--PKANC--SHFCIDRRD 5170
+ C P C ++ C D D
Sbjct: 2773 STSQCIHPSWKCDGTNDCYDGSD 2795
Score = 47.0 bits (110), Expect = 0.006
Identities = 87/381 (22%), Positives = 151/381 (38%), Gaps = 29/381 (7%)
Frame = -1
Query: 5199 CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRND------TIEAEILMV--YGHRLKLFT 5044
C C+ + +C C+ GYIL EN K CR + T + + V Y +
Sbjct: 1953 CESLCLSKDQKTFECACSQGYIL-ENGK-CRSPEKRVIYVTDDGSVQSVGWYKDQKSGEM 2010
Query: 5043 IDGHAKATLLSNLTNG--VALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSL 4870
+ +L S++ V L D K D++Y ++ + + + +I S
Sbjct: 2011 VQVMRAHSLHSDIGKKRIVRLVADTKKDVIYVVTRQNE-----VWKCATNGSFAHMIYST 2065
Query: 4869 PTKGIDGIAVDWLGRNIYYTDRNHDA----IAVCD----MRGRFNRILLKGTPLNDPRAI 4714
+ I I++D + ++ + R + I + D G ++ I+ + P I
Sbjct: 2066 TSHRIAAISLDRVTGHLLVSARESVSSKGDIVLLDPDRYQEGMYSVIVEDEEKV--PYEI 2123
Query: 4713 VLDPLQALVFWTDWGASAH-IGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDA 4537
+DP + +FW ASAH I N DGS + I+ + +AVD RL + D+
Sbjct: 2124 AVDPPKGKIFW----ASAHCIKAANYDGSEPKCIVAKSAVA---TIAVDEDRSRLCYMDS 2176
Query: 4536 HRDYIASCNYDGSKRR----MVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTN 4369
R + +Y+G + M + + +L+ D +++ D N + V I +
Sbjct: 2177 ERAAVDCVDYNGENEQRNVAMFKAQGLAEVVSLSFNGDEMFFFDKFNSSGSIVRGIVQKD 2236
Query: 4368 RKVLIQD---KQYRPMGFKIVHPSL--QSMGSLKTARHPCS-QPARCDNLCIPANTPDLT 4207
V+ D KQ +I+ + Q L TA CS C++LCI D
Sbjct: 2237 GSVVFVDSIKKQLPRQKLRIIDFDIMDQKKSVLFTA---CSNNNGGCEHLCITVPFED-- 2291
Query: 4206 TSSDNFTCMCAQGFRSEGRSC 4144
S C+C +E +C
Sbjct: 2292 --SIKKKCICVHSVPTEDGTC 2310
Score = 42.0 bits (97), Expect = 0.20
Identities = 66/289 (22%), Positives = 104/289 (35%), Gaps = 47/289 (16%)
Frame = -1
Query: 1287 CYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQNCVGHE-------CLNGGFCSYANSNR 1129
C CF+ G ++C C DG+ CV E C + NS +
Sbjct: 878 CEHFCFATSCKGSVGCEPVKCGCADGMKLVDNGKCVKDEHWEDPNGCDEDREFTCLNSRK 937
Query: 1128 SLPHC-ICPS----GFTGDHCEEYLCKDACPFGSKCTYDITK--PMDPITCSCEQNAAAH 970
+P +C G D +CKD G+K D T P++ C + +
Sbjct: 938 CIPKANLCDGDDDCGDGSDEDSNGICKDFKCVGNKFQCDSTTCIPLE-FLCDGKSDCNDG 996
Query: 969 NTDCSPICQKQPNWCHNGG--RCLDTPGYPGKCKCLPRFAGPRCDVPVQC-----DDYCT 811
+ +C+ P+ + G RC +T KC+ + RC+ C ++ C
Sbjct: 997 TDELETMCKTVPDVRCSVGQFRCSNT-------KCIDK--SKRCNGIQDCENGSDEEDCP 1047
Query: 810 NNSKCTITN---GTHF------ECD----CKPGFKGLRCEQETKCSECSNEAKCIKKPS- 673
+ CT T GT CD C G CE+ C + + +C K S
Sbjct: 1048 RSKLCTPTEFRCGTGLCIKQSQVCDGKMQCLDGLDEKHCEENNSCIK-GRQFRCANKQST 1106
Query: 672 ---------GTVICQCPQGLGGEYCEKITATSC---HQLECKNGGYCLK 562
G C+ E+C+ T++SC +Q C + G CL+
Sbjct: 1107 CLDMIFQCDGVPDCEDESDESPEFCKGNTSSSCAKMNQFMCAD-GKCLR 1154
Score = 39.7 bits (91), Expect = 1.0
Identities = 78/356 (21%), Positives = 113/356 (30%), Gaps = 48/356 (13%)
Frame = -1
Query: 1479 CHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCP-KDEPHCRSYSFCECDKGWTGPHCRHK 1303
C S+ + C C+G G C+ V C D C D+ W P+ +
Sbjct: 871 CSTSSSNCEHFCFATSCKGSVG----CEPVKCGCADGMKLVDNGKCVKDEHWEDPNGCDE 926
Query: 1302 ADAKVCYGH--CF-SGGACDGEGPLNLRCSCGDGLTGNRCQNCVGHECLNGGFCSYANSN 1132
C C CDG+ CGDG + C +C+ F +S
Sbjct: 927 DREFTCLNSRKCIPKANLCDGDD------DCGDGSDEDSNGICKDFKCVGNKF--QCDST 978
Query: 1131 RSLPHCICPSGFTGDHCEEYLC--KDACPFGSKCTYDITKPMDPITCSCEQNAAAHNTDC 958
+P E+LC K C G+ + K + + CS Q + NT C
Sbjct: 979 TCIPL-------------EFLCDGKSDCNDGTDELETMCKTVPDVRCSVGQFRCS-NTKC 1024
Query: 957 ---SPICQKQPNWCHNGGRCLDTPGY----PGKCKC---LPRFAGPRCDVPVQCDD---- 820
S C + C NG D P P + +C L CD +QC D
Sbjct: 1025 IDKSKRCNGIQD-CENGSDEEDCPRSKLCTPTEFRCGTGLCIKQSQVCDGKMQCLDGLDE 1083
Query: 819 -YCTNNSKCTITNGTHFECDCKPGF---KGLRCEQETKCSECSNEAKCIKKPSGTVIC-- 658
+C N+ C G F C K +C+ C + S+E+ K + + C
Sbjct: 1084 KHCEENNSCI--KGRQFRCANKQSTCLDMIFQCDGVPDCEDESDESPEFCKGNTSSSCAK 1141
Query: 657 ----------------------QCPQGLGGEYCEKITATSCHQLECKNGGYCLKPD 556
C G + C S L C NG C+ +
Sbjct: 1142 MNQFMCADGKCLRSFQLCDGFPDCLTGEDEKECPPSMCNSATHLSCANGNKCVSKE 1197
>gi|31239543|ref|XP_320185.1| ENSANGP00000011153 [Anopheles gambiae]
gi|30174007|gb|EAA00393.2| ENSANGP00000011153 [Anopheles gambiae str.
PEST]
Length = 4569
Score = 890 bits (2300), Expect = 0.0
Identities = 672/2311 (29%), Positives = 986/2311 (42%), Gaps = 145/2311 (6%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCTCNE-NEFRCQSGA 6394
DE +C+ R C G+F C N CIP+ + CN I +C + +DE C+CN FRC G
Sbjct: 2420 DELVTFCAHRPCPDGFFRCNNARCIPKNQQCNHIQNCGDGSDEVGCSCNNATHFRCTDGQ 2479
Query: 6393 CIPSKARCNHMQDCNDASDEIGCP-FRNCSALNEFGMTGLINCATTSQCIHPSWKCDGTN 6217
CI RC++ DC D SDEIGCP RNC+ G +NCA T+ C P+W+CDG N
Sbjct: 2480 CIVKSMRCDYEPDCKDVSDEIGCPVMRNCTE-------GFVNCANTTGCYMPTWRCDGEN 2532
Query: 6216 DCYDGSDEKDCFVEF-----------------------------DATGGSVSAPRSCDAK 6124
DC+D SDE+DC DATGG +S+ K
Sbjct: 2533 DCWDNSDEQDCPTAIPTCPEDKFLCANGRCIPQSWRCDDEDDCTDATGGGLSSDELACVK 2592
Query: 6123 ----TQFACLATRTCMPKHWQCDGQPDCADGSDE-KNCDAKKCTSFEFSCESSKKCIPLE 5959
QF C T C+ WQCDG PDCADGSDE +C + C EF C ++ +CIP +
Sbjct: 2593 HCKPNQFKCTNTSECISNSWQCDGHPDCADGSDEGDHCSRRDCPETEFQCPTTNRCIPQK 2652
Query: 5958 QKCDGRRDC-PDGEDEHQCETECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLG 5782
CDG DC +DE C+ ++ +F C N CI + CDG DC+D G
Sbjct: 2653 WVCDGEVDCGATQDDEMGCDEMMVNECDKTSFTCKNGECISLLHVCDGEQDCVD-----G 2707
Query: 5781 SDEVDCAAGRTSFHVPSRCADETCVVACELTAVLCDGIQDCSDGFDEKNCASLDRQC--K 5608
SDE P C ++ DG+DE+ A +D +
Sbjct: 2708 SDE------------PLYC-------------------KEGDDGYDEEEGAGVDDHLCVE 2736
Query: 5607 PNEWMCDSGQCIDSGRLCDASVDCVDGSDEWVEICS-----LSEPPRRGCPSGWSCLLTN 5443
P+ + C++G+CI+ C+ + DC DGSDE + +C + P C SG
Sbjct: 2737 PDHFRCNNGRCIERNLTCNVNDDCADGSDEDIRLCRNTTLICAGPDLFRCESG------- 2789
Query: 5442 GTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSSTRNSCDQTWNCQ-RHAGFESCSCDD 5266
C+ LCDG DC DE+ C + C C+ R G+E C C
Sbjct: 2790 ---ACITSNMLCDGANDCGDWSDEKSCQVN-ECEMIPDLCAH--ECEDRPVGYE-CVCRK 2842
Query: 5265 GYHLSPYDKKTCLRSPSCPKAN---CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDT 5095
G+ ++ DK C+ C + C+ C++ H C C G++L +N CR
Sbjct: 2843 GFRVNVNDKHLCVDVDECTEQQPRPCTQTCVNTHGSYH-CTCLDGFVLRDNDT-CRAEGR 2900
Query: 5094 IEAEILMVYGHRLKLFTIDGHAKATLLS-NLTNGVALDYDVKSDLVYWTDVAHDGNKAGI 4918
+++ +R L +D T+L+ NLTN + LD+D K + YW+DV
Sbjct: 2901 HILPPKLIFSNRYYLREVDLSGGMTILAHNLTNAITLDFDWKDECYYWSDVTRTVTTVKR 2960
Query: 4917 TSMSNQPNT-YRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKG 4741
S + N VI+ K +G+AVDW+GRN+Y+ D+ D I V + GR+ R+L+
Sbjct: 2961 MCESGEENRPVEVIHRTNLKNPEGLAVDWVGRNLYWCDKGLDTIEVSKLDGRYRRVLIN- 3019
Query: 4740 TPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPA 4561
L PRAI LDP + ++WTDWG HIGR MDGSN+ ++++++ + WPNAL +
Sbjct: 3020 KELQKPRAIALDPYRRYMYWTDWGDQPHIGRAGMDGSNQTILIKEQ-LGWPNALTISFET 3078
Query: 4560 QRLYFGDAHRDYIASCNYDGSKRRMVLRGS------VRHIFALAVFEDYVYWSDWHNHTI 4399
+L++GDA DYIA + DG R++L + + H+FA+AV+ED +YWSD + +I
Sbjct: 3079 NQLFWGDAREDYIAVSDLDGQNVRILLSRARQPTLNLHHVFAIAVWEDRIYWSDLDSKSI 3138
Query: 4398 ERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDNLCIPANT 4219
E HK G LI + +RPM ++ H Q L+ +PC A C LC+
Sbjct: 3139 EYCHKFRGDGCGTLI-NTIHRPMDIRVFHYYRQ----LQPEVNPCDT-AGCQTLCV---- 3188
Query: 4218 PDLTTSSDNFTCMCAQGF--RSEGRSCVSECKPNDFVCTKTYKCISSWWRXXXXXXXXXX 4045
L+ + C+C F ++G+SC + C F C T+KCI +WR
Sbjct: 3189 --LSPDPPGYRCLCPDNFILTADGKSCAANCSAAHFQCRTTFKCIPFYWRCDKQDDCGDG 3246
Query: 4044 XXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCEN 3865
CP F C AGQF C +C+ S++CDGV C DE C+
Sbjct: 3247 SDE----PPNCPTFTCEAGQFQC------LNKRCINPSQICDGVDQCGDLSDERD--CDR 3294
Query: 3864 FECTEAQFKCGDKKK------CIPLTSVCDKEKDCDDGSDELNCEITSCKPDFFACFNGT 3703
FEC + FKCG CI CD+E +C +G DE NCE +C F C NG
Sbjct: 3295 FECFSSHFKCGPSAAKNTSGFCIEGARRCDEEVNCPNGEDEQNCEPKNCTATQFRCANG- 3353
Query: 3702 AISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQCDGTLDCR 3523
+CI + + CD DC +G DE C C +F+C+ G+CIP+ CD DC
Sbjct: 3354 --GRCIDRTWVCDNVPDCHDGSDE-QVCGPATTCPEHEFRCSEGRCIPQSWLCDDEKDCA 3410
Query: 3522 DGSDE-KGCKKECAIVCD--------NSCVHADDLCDGKKKCNDGSDEDEEACVIKQLLE 3370
+G DE + C+K AI C+ + C+ CD + C D SDE C ++ E
Sbjct: 3411 NGEDETENCQKPEAITCEPTSFRCNNSKCIPGRWRCDFENDCGDNSDELN--CELRNCSE 3468
Query: 3369 KENRKCGGFA------CDGIVDCEDGSDEKGC------PDLEC--HLA--SNKSLICDGT 3238
E R G CD +C D SDE+ C +C H A SNK CDG
Sbjct: 3469 SEFRCRDGHCIRGIRRCDNEFNCADHSDEENCNVTCSAEQFKCKSHPACISNK-FKCDGD 3527
Query: 3237 IDCSSGKDENNCH-NNGESNFFQCSMQT--IKEWQVCDGRWDCADGLDESPEMCASRKAR 3067
DC DE +C GE ++C+ + W VCDG DC D DE E C ++
Sbjct: 3528 NDCIDESDEEDCECQEGE---YRCNNGKCILSSW-VCDGIDDCLDNSDEMGEYC--KEHG 3581
Query: 3066 CFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKGKYRC-TNGRCIDVSAR 2890
C + + + C+ S +CD DC D SDE C +RC ++ +CID++ R
Sbjct: 3582 CNKRAFRCANRNCIRKSL-MCDNKDDCGDNSDEKSALCHKCPPNSFRCNSDSKCIDIALR 3640
Query: 2889 XXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENE-CEPL 2713
FG C+Q C H C CA GY + N C +
Sbjct: 3641 CDQTPHCLDESDEIGCIKTGCGFGACSQLCIEKKGHYT-CRCAEGYVKGGPGRNATCVAV 3699
Query: 2712 SKSAEMFITNGNRLHLMS--------LENSQVSVLRPVFNI-KMNLIPGGIDFGYD---- 2572
+ + + + + + L+ S + + R F I + N+ ID YD
Sbjct: 3700 DEQGILLVASESDFRSLYADTPVMGYLQTSSLKIDRFDFAITRHNITLFWID-SYDTSIN 3758
Query: 2571 -VFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGLITYDFMHNNVYFTESSEQ 2395
+ T + G + + +K +G S + T D H++V +
Sbjct: 3759 KILMDTTVKDGGDYSRSPPVDKRKIVRRGLGPAPAPPSYDRIKTLDGKHSSVVLKDDEIH 3818
Query: 2394 NRGVLFD-----------RQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTT 2248
+ D +++NI+V T+ TL I+ L VDP+ ++ W+
Sbjct: 3819 PIAIACDWLTERLYVINKKRSNIFVMSFNGTNHTTLTATGKHPID-LVVDPVSGMMVWSI 3877
Query: 2247 SAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRT 2068
+ I+S+ +DG+ G Q LV N+ + + +D + +RLYW D K T
Sbjct: 3878 ---METIISSGMDGR--------GKQK---LVHTNVEWASGLAIDTTTKRLYWADYRKST 3923
Query: 2067 IET-VSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITRQGSIHRMHKFTGKTNKYVQKI 1891
IET + G DR + + P +DV +Y+I +I +++K+ Y+ +
Sbjct: 3924 IETCLLLTGGDRHVIAELHDYSKPKLLDVFEDSVYVILYNQNILKLNKYGRDNGTYMNEE 3983
Query: 1890 REVSPRI------QIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKC 1729
+ + + HP KH S NPC C ++TVC+ L C
Sbjct: 3984 ARGAGGLAGYRSSDVHFIHPLKHDRS----VPNPCIISPCHNSTVCLLSTVSR--LKRAC 4037
Query: 1728 LCGPGRFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCSPQKTCVCPPGFYGRQCEINE 1549
+C R V ++ E +C D + E
Sbjct: 4038 VCPDARPRIVFDER--------GEVKECLDL-----------------------PAQAPE 4066
Query: 1548 CSETCWNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEP 1369
C C NG TC + G C C +++ C +C G C +G C+ V EP
Sbjct: 4067 CKLHCNNG-TCFIDTDGQQK---CKCSASFDGKYCDHYICSGYCKNKGFCELV---NGEP 4119
Query: 1368 HCRSYSFCECDKGWTGPHCRHKADAKVCYGHCFSGGAC-----DGEGPLNLRCSCGDGLT 1204
C C WTG C C +C +GG C DG +L CSC G T
Sbjct: 4120 QCT------CLPQWTGKRC--DISTNKCQRYCHNGGNCTIVQRDGG---SLSCSCPVGYT 4168
Query: 1203 GNRCQNCVGHECLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDI 1024
G +C++C C NGG C ++RS C+C G+ G +CE+ +C + C G +CT +
Sbjct: 4169 GEQCEHCSNLRCENGGVCRKTTTDRS--QCLCAEGYVGRNCEKNVCTEFCENGGECTIE- 4225
Query: 1023 TKPMDPITCSCEQNAAAHNTDCSPICQKQ--PNWCHNGGRCLDTPGYPGKCKCLPRFAGP 850
CSC +N CQ + + C NGG C+ PG CKC + GP
Sbjct: 4226 ---RGAAKCSCPENTYGER------CQLRQCADLCRNGGDCV--PGERPYCKCRQGYEGP 4274
Query: 849 RCDVPVQCDDYCTNNSKCTITNGTH--FECDCKPGFKGLRCEQETKCS--ECSNEAKCIK 682
C+ + C + GT + +P + + C C+N C+
Sbjct: 4275 YCE-----------HDLCELPEGTRPSYCSTIRPTTEPSAHPPSSSCGSYSCNNGGHCL- 4322
Query: 681 KPSGTVICQCPQGLGGEYCEK--ITATSCHQLECKNGGYCLKPDP--SANRT-SPTCLCS 517
+ G IC C GE+CE + C++ C N G C S+N T P+C+C
Sbjct: 4323 EVRGKPICNCTMQYAGEHCENYVMYLNPCNRY-CMNNGICQLDLGFFSSNVTYIPSCVCI 4381
Query: 516 PGFKGLLCS-SNACENFCLHDGNCTLDEYFEPQCECYQAFIGDRCQYRIHQHAV--IFSD 346
+ G C C C G C ++ +C C + CQ + + + S+
Sbjct: 4382 GEWTGHKCDLPPRCVGEC---GTC-IEGSSINECICDDNPVPYPCQQVVSLSELERMESN 4437
Query: 345 DDSGWIKSFXXXXXXXXXXXXXXXIFANRSNRFAVFRQFRHNPLQNQGAPVDQFSNPAYL 166
D S + R + F H L + + +NP YL
Sbjct: 4438 DSSYTLSVLAIALFVILIVAAGFGGTIYGLRRRRTGQPFLHARLTDN----VEITNPMYL 4493
Query: 165 IDEGGIELVTQNTSLVSSHDRGSFNNPVFEQ 73
D + + V D+ F NPV+EQ
Sbjct: 4494 GD------ADEGPAFVHEDDKVHFGNPVYEQ 4518
Score = 326 bits (836), Expect = 4e-87
Identities = 421/1722 (24%), Positives = 632/1722 (36%), Gaps = 162/1722 (9%)
Frame = -1
Query: 5157 CFCAPGYILSENQKDCRRNDTI---EAEILMVYGHRLKLFTIDGHAKATLLSN-LTNGVA 4990
C C+ G I S + K C + + + H I+G S+ L N +A
Sbjct: 2047 CACSHGKISSADLKTCEPYENFLIFSRQSAIESIHMTDANNINGPIPEIKNSSYLKNTIA 2106
Query: 4989 LDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYT 4810
L YD + L++++D+ H N N R++ T ++G+A + L R +++T
Sbjct: 2107 LSYDYEQQLIFYSDIDHSTINC---VFFNGTNHRRIVTKQLT--VEGLAFNVLTRVLFWT 2161
Query: 4809 DRNHDAIAVCDMR----------GRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGA-S 4663
N AI D+ + ++K + PR I ++P A+V+WT+W +
Sbjct: 2162 SNNEAAIRSLDLNKASLTDPAANAELVQDVIKLRATDKPRGIAVEPCLAMVYWTNWNQHA 2221
Query: 4662 AHIGRMNMDGSN-EQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRM 4486
A I R G E +I D I+ PNAL +D A++LY+ DA D + +YDG R +
Sbjct: 2222 ASIQRAYPSGYGLESIITSD--IQMPNALTLDYQARKLYWADALLDKVERTDYDGKHRVV 2279
Query: 4485 VLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPS 4306
+ + +H FALAVF D ++W+D H + R +K +G++ +L +D +PMG V
Sbjct: 2280 LAHSTPKHPFALAVFGDLLFWTDLTVHAVIRANKYSGSDIVLLRRDIA-QPMGIVAVQQI 2338
Query: 4305 LQSMGSLKTARHPCS-QPARCDNLCIPANTPDLTTSSDNFTCMCAQG-FRSEGRSC---- 4144
+ + PC C+++C L ++ C C QG ++G+ C
Sbjct: 2339 -----DKECSADPCQVMNGFCEDVC-------LIDAAGKVECHCTQGVLAADGQRCIPKS 2386
Query: 4143 VSECKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTA 3964
VS C ++F CT G C PF
Sbjct: 2387 VSNCSSSEFSCTN----------------------------GNCIPFHLT---------- 2408
Query: 3963 QNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKK------------- 3823
CDGVK+C G DE FC + C + F+C + +
Sbjct: 2409 -------------CDGVKNCLDGSDELVTFCAHRPCPDGFFRCNNARCIPKNQQCNHIQN 2455
Query: 3822 -----------------------KCIPLTSVCDKEKDCDDGSDELNCEI-TSCKPDFFAC 3715
+CI + CD E DC D SDE+ C + +C F C
Sbjct: 2456 CGDGSDEVGCSCNNATHFRCTDGQCIVKSMRCDYEPDCKDVSDEIGCPVMRNCTEGFVNC 2515
Query: 3714 FNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQCDGT 3535
N T C + CDGE+DC + DE D I C ++F C +G+CIP+ +CD
Sbjct: 2516 ANTTG---CYMPTWRCDGENDCWDNSDEQDCPTAIPTCPEDKFLCANGRCIPQSWRCDDE 2572
Query: 3534 LDCRD------GSDEKGCKKEC---AIVCDNS--CVHADDLCDGKKKCNDGSDEDEEACV 3388
DC D SDE C K C C N+ C+ CDG C DGSDE + C
Sbjct: 2573 DDCTDATGGGLSSDELACVKHCKPNQFKCTNTSECISNSWQCDGHPDCADGSDEGDH-CS 2631
Query: 3387 IKQLLEKE-----NRKC--GGFACDGIVDC-EDGSDEKGCPDL---ECHLAS-------- 3265
+ E E +C + CDG VDC DE GC ++ EC S
Sbjct: 2632 RRDCPETEFQCPTTNRCIPQKWVCDGEVDCGATQDDEMGCDEMMVNECDKTSFTCKNGEC 2691
Query: 3264 -NKSLICDGTIDCSSGKDENNCHNNGESNF------------------FQCSM-QTIKEW 3145
+ +CDG DC G DE G+ + F+C+ + I+
Sbjct: 2692 ISLLHVCDGEQDCVDGSDEPLYCKEGDDGYDEEEGAGVDDHLCVEPDHFRCNNGRCIERN 2751
Query: 3144 QVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDEN 2965
C+ DCADG DE +C + C + S LCDG DC D SDE
Sbjct: 2752 LTCNVNDDCADGSDEDIRLCRNTTLICAGPDLFRCESGACITSNMLCDGANDCGDWSDEK 2811
Query: 2964 ----------PIHCKDMCKGK---YRCTNGRCIDVSARXXXXXXXXXXXXXXXXGAEC-- 2830
P C C+ + Y C + V+ EC
Sbjct: 2812 SCQVNECEMIPDLCAHECEDRPVGYECVCRKGFRVNVNDKHLCVDVD---------ECTE 2862
Query: 2829 HHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLE- 2653
C Q C + + + C C G+ ND E I + NR +L ++
Sbjct: 2863 QQPRPCTQTC-VNTHGSYHCTCLDGFVLRDNDTCRAEGRHILPPKLIFS-NRYYLREVDL 2920
Query: 2652 NSQVSVLRPVFNIKMNLIPGGIDFGY---DVFRTTL----MYTVGIGNSRVDI---RSKK 2503
+ +++L + L D Y DV RT M G N V++ + K
Sbjct: 2921 SGGMTILAHNLTNAITLDFDWKDECYYWSDVTRTVTTVKRMCESGEENRPVEVIHRTNLK 2980
Query: 2502 WSDGLIGSWGEEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRT 2323
+GL W + N+Y+ + I V+K R
Sbjct: 2981 NPEGLAVDW--------------VGRNLYWCDKGLD----------TIEVSKLDGRYRRV 3016
Query: 2322 LIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERN 2143
LI ++A+DP +R ++WT P I A +DG L++
Sbjct: 3017 LINKELQKPRAIALDPYRRYMYWTDWGDQPHIGRAGMDG-----------SNQTILIKEQ 3065
Query: 2142 IFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDT-----PVTMDVLG 1978
+ P ++ + F +L+W D + I DG++ R + T + V
Sbjct: 3066 LGWPNALTISFETNQLFWGDAREDYIAVSDLDGQNVRILLSRARQPTLNLHHVFAIAVWE 3125
Query: 1977 GYIYLITRQG-SIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQ 1801
IY SI HKF G + I + + IRV H + + + NPC
Sbjct: 3126 DRIYWSDLDSKSIEYCHKFRG--DGCGTLINTIHRPMDIRVFHYYR----QLQPEVNPCD 3179
Query: 1800 SDYCPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQC--GDYFCY 1627
+ C T+CV D G +CLC K C A+ C + C
Sbjct: 3180 TAGC--QTLCVLSPDPPGY---RCLCPDNFILTADGKSC---------AANCSAAHFQCR 3225
Query: 1626 NNAGCSPQKTCVCPPGFYGRQCEINECSETCWNGE-----TCAVQEFGSTTNVVCHCPSN 1462
C P FY R + ++C + TC +F N C PS
Sbjct: 3226 TTFKCIP---------FYWRCDKQDDCGDGSDEPPNCPTFTCEAGQF-QCLNKRCINPS- 3274
Query: 1461 YTQSSCATNVCEGV--CGPRGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHKADAKV 1288
+C+GV CG DE C + C GP + AK
Sbjct: 3275 --------QICDGVDQCGDL---------SDERDCDRFE-CFSSHFKCGP-----SAAKN 3311
Query: 1287 CYGHCFSGG-ACDGEGPLNLRCSCGDGLTGNRCQNCVGHE--CLNGGFC---SYANSNRS 1126
G C G CD E + C G+ +NC + C NGG C ++ N
Sbjct: 3312 TSGFCIEGARRCDEE----VNCPNGEDEQNCEPKNCTATQFRCANGGRCIDRTWVCDN-- 3365
Query: 1125 LPHCICPSGFTGDHCEEYLCKDA--CP-FGSKCTYDITKPMDPITCSCEQNAAAHNTDCS 955
+P C D +E +C A CP +C+ P + C E++ A+ D +
Sbjct: 3366 VPDC-------HDGSDEQVCGPATTCPEHEFRCSEGRCIPQSWL-CDDEKD-CANGEDET 3416
Query: 954 PICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSKCTITNGTH 775
CQK C T KC+P RCD C D ++ C + N +
Sbjct: 3417 ENCQKP-----EAITCEPTSFRCNNSKCIP--GRWRCDFENDCGDN-SDELNCELRNCSE 3468
Query: 774 FECDCKPG--FKGL-RCEQETKCSECSNEAKCIKKPSGTVICQCPQGLGGEYCEKITATS 604
E C+ G +G+ RC+ E C++ S+E C V C Q C+ A
Sbjct: 3469 SEFRCRDGHCIRGIRRCDNEFNCADHSDEENC------NVTCSAEQ----FKCKSHPACI 3518
Query: 603 CHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSSNAC 478
++ +C C+ + C C G C++ C
Sbjct: 3519 SNKFKCDGDNDCIDESDEED-----CECQEG--EYRCNNGKC 3553
Score = 265 bits (676), Expect = 1e-68
Identities = 223/724 (30%), Positives = 294/724 (39%), Gaps = 14/724 (1%)
Frame = -1
Query: 6270 CATTSQCIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTC 6091
C CI + CDG DC DGSDE+ T +CD + F C R C
Sbjct: 891 CRNKIDCIEIKYTCDGDRDCEDGSDEE--------TTPDGPCDPNCDLERNFKCDEQR-C 941
Query: 6090 MPKHWQCDGQPDCADGSDEK--NCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDC--PDG 5923
+ + CDG DC D SDE NC K C+ F CE S +CIP CD DC D
Sbjct: 942 ISRSHVCDGSVDCIDESDEDYINCPNKTCSEHFFQCEVSHRCIPNTWVCDRHLDCGPNDS 1001
Query: 5922 EDEHQCETECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSF 5743
DE + +C F C N C+P + CDG D+C
Sbjct: 1002 SDEPEHCHKCPE------FECKNSACVPFEFLCDGVDNC--------------------- 1034
Query: 5742 HVPSRCADETCVVACELTAVLCDGIQDCSDGFDEK-NCASLDRQCKPNEWMCDSGQCIDS 5566
V ++C T LC+G DC DG DE CA
Sbjct: 1035 GVTNQCIKVT---------QLCNGRTDCPDGTDEGFRCAE-------------------- 1065
Query: 5565 GRLCDASVDCVDGSDEWVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCM 5386
+LCDA DC P G C C L RDC
Sbjct: 1066 -KLCDAPNDCSHAC--------------HNAPEGLIC-------SCPAHLFLQPNGRDC- 1102
Query: 5385 SGIDEQCDNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPK 5206
G D CDN G CS C + C C +GY L YDK TC
Sbjct: 1103 -GHDHACDN-WGTCSQI---------CTKAGTHYRCGCVEGYTLM-YDKFTC-------- 1142
Query: 5205 ANCSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAK 5026
R + G +P I S Q EIL V + L +
Sbjct: 1143 ---------RSNNGD----SPYVIFSNRQ-----------EILGVDLNTLGV-------- 1170
Query: 5025 ATLLSNLTNGVALD--YDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGID 4852
+ ++L N +ALD Y +S ++W+DV D G N V+ S +
Sbjct: 1171 RSFYTSLRNTIALDFLYRNESVQIFWSDVMDDKIYRGTLRNDTLSNVEAVVQS-GLSTAE 1229
Query: 4851 GIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDW 4672
G+AVDW+G NIY+ D N D I V G F R L+ G +N PRAI LDP++ ++FWTDW
Sbjct: 1230 GLAVDWIGMNIYWIDSNLDQIEVAKTNGSFRRTLVAGDMVN-PRAIALDPMEGVLFWTDW 1288
Query: 4671 -GASAHIGRMNMDGSNEQVI-LQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGS 4498
S + R M G N VI WPN +A+D +R+Y+ DA D I + YDG
Sbjct: 1289 EEGSPRLERCTMAGENRTVIKYVGSDGGWPNGIALDYIPRRVYWIDARSDSIHTITYDGQ 1348
Query: 4497 KRRMVLR--GSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGF 4324
+V++ G + H F++ VF++YVYW+DW +++ R +K GT+ V IQ Q +P G
Sbjct: 1349 DHHLVIKDQGVLAHPFSITVFDNYVYWTDWRTYSVIRANKWNGTDVNV-IQKTQSQPFGI 1407
Query: 4323 KIVHPSLQSMGSLKTARHPCS-QPARCDNLCIPANTPDLTTSSDNFTCMCAQGFR--SEG 4153
+I+H S Q T +PC+ C +LC L + C C R +
Sbjct: 1408 QILHSSRQP----NTQPNPCADNNGGCSHLC-------LLSVGSRHECACPHVMRLHEDR 1456
Query: 4152 RSCV 4141
R CV
Sbjct: 1457 RQCV 1460
Score = 196 bits (498), Expect = 6e-48
Identities = 185/693 (26%), Positives = 290/693 (41%), Gaps = 32/693 (4%)
Frame = -1
Query: 5160 QCFCAPGYILSENQKDCRRNDTIEAEILMVYGHR----LKLFTIDGHAKATL--LSNLTN 4999
QC C+PGY L + + C I+ ++Y ++ F + ++ + +++L
Sbjct: 535 QCMCSPGYRL-KTKSQCV---LIKRPTFLLYAKSNPAMIRGFAVGIKSQEAIVPITDLGP 590
Query: 4998 GVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNI 4819
+ DY V+ L++++ D I + ++ P DGI+ DWLG NI
Sbjct: 591 HITFDYHVEDQLIFFSHGVIDKPSFRIEAQKLDGTQRELLLESPGS-CDGISYDWLGNNI 649
Query: 4818 YYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGA-SAHIGRMN 4642
++TD + + I+V + + R + L P++IV+DP Q ++W+ W S I R
Sbjct: 650 FWTDSDRNHISVIKLGPKRMRYTVL-RQLYAPKSIVVDPKQGWMYWSSWSVPSGRIDRAW 708
Query: 4641 MDGSNEQVIL--QDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSV 4468
M+G+ ++++ ++R I WP L++D +RLY+ DA +I S N DGS R ++ G
Sbjct: 709 MNGTQPELLVSSKERPIEWPTGLSIDMIQKRLYWCDARLSFIESINLDGSNRVLLFDGRS 768
Query: 4467 RHIF--ALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSM 4294
++ F ALAV +Y++D IE+++ ++ + I ++ + +G KI Q
Sbjct: 769 QNQFPVALAVHRQLLYFADNVKGHIEKLN-LSDPHLLETITIEKPQVLGLKIFDNLTQYG 827
Query: 4293 GSLKTARHPCSQPARCDNLCIPANTPDLTTSSDNFTCMCAQG----FRSEGRSCVSECKP 4126
G+ R+ C C +C+ NTP S C C G SEG+ C P
Sbjct: 828 GN---GRNACE--IDCPGICL--NTPVAVAS-----CKCEDGQVLSLSSEGKPVA--CVP 873
Query: 4125 ND-------------FVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQ 3985
D F+C CI + +G C P +
Sbjct: 874 FDLQHSLASCNNSTHFLCRNKIDCIEIKYTCDGDRDCEDGSDEETTPDGPCDPNCDLERN 933
Query: 3984 FVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLT 3805
F C +C+ S +CDG DC DE+ C N C+E F+C +CIP T
Sbjct: 934 FKCDEQ------RCISRSHVCDGSVDCIDESDEDYINCPNKTCSEHFFQCEVSHRCIPNT 987
Query: 3804 SVCDKEKDC--DDGSDE-LNCEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQD 3634
VCD+ DC +D SDE +C K F C N S C+P EF CDG D+C
Sbjct: 988 WVCDRHLDCGPNDSSDEPEHCH----KCPEFECKN----SACVPFEFLCDGVDNCG---- 1035
Query: 3633 EPDSCFGIGECTHEQFQCTSGKCIPKRRQCDGTLDCRDGSDEKGCKKECAIVCDNSCVHA 3454
+ +CI + C+G DC DG+DE E N C HA
Sbjct: 1036 ------------------VTNQCIKVTQLCNGRTDCPDGTDEGFRCAEKLCDAPNDCSHA 1077
Query: 3453 DDLCDGKKKCNDGSDEDEEACVIKQLLEKENRKCG-GFACDGIVDCEDGSDEKGCPDLEC 3277
C++ + +C L+ R CG ACD C + G C
Sbjct: 1078 ---------CHNAPEGLICSCPAHLFLQPNGRDCGHDHACDNWGTCSQICTKAG-THYRC 1127
Query: 3276 HLASNKSLICDGTIDCSSGKDENNCHNNGESNF 3178
+L+ D C S NNG+S +
Sbjct: 1128 GCVEGYTLMYD-KFTCRS--------NNGDSPY 1151
Score = 174 bits (442), Expect = 2e-41
Identities = 111/323 (34%), Positives = 143/323 (43%), Gaps = 9/323 (2%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGY-FNCGNGLCIPEQKVCNRINDCANFADES-NC------TCNEN 6418
D D + C P + F C G CIP+ +C+ DCAN DE+ NC TC
Sbjct: 3371 DGSDEQVCGPATTCPEHEFRCSEGRCIPQSWLCDDEKDCANGEDETENCQKPEAITCEPT 3430
Query: 6417 EFRCQSGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPS 6238
FRC + CIP + RC+ DC D SDE+ C RNCS +EF CI
Sbjct: 3431 SFRCNNSKCIPGRWRCDFENDCGDNSDELNCELRNCSE-SEFR-------CRDGHCIRGI 3482
Query: 6237 WKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQP 6058
+CD +C D SDE++C V +C A+ QF C + C+ ++CDG
Sbjct: 3483 RRCDNEFNCADHSDEENCNV-------------TCSAE-QFKCKSHPACISNKFKCDGDN 3528
Query: 6057 DCADGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGG 5878
DC D SDE++C+ C E+ C + KCI CDG DC D DE C G
Sbjct: 3529 DCIDESDEEDCE---CQEGEYRCNNG-KCILSSWVCDGIDDCLDNSDE--MGEYCKEHGC 3582
Query: 5877 N-ATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVA 5701
N FRC N CI + CD DDC DN+ + C + S+C D
Sbjct: 3583 NKRAFRCANRNCIRKSLMCDNKDDCGDNSDEKSALCHKCPPNSFRCNSDSKCID------ 3636
Query: 5700 CELTAVLCDGIQDCSDGFDEKNC 5632
A+ CD C D DE C
Sbjct: 3637 ---IALRCDQTPHCLDESDEIGC 3656
Score = 163 bits (412), Expect = 6e-38
Identities = 169/654 (25%), Positives = 250/654 (37%), Gaps = 17/654 (2%)
Frame = -1
Query: 6012 CTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNATFRCT-NHRCIPM 5836
C+ +F+C KCIP +CD DC DG DE C+ G F CT ++RCIP
Sbjct: 3 CSQSQFTCVMDGKCIPALWRCDTSADCSDGSDEVGCDKAHACNEG--MFHCTVSNRCIPH 60
Query: 5835 AWRCDGTDDC-----MDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACELTAVLCDG 5671
W CDG DC D D C A + C+D C+ CDG
Sbjct: 61 DWTCDGDVDCGLVEKYDMVDVSDEDPQLCRAHTKCLPTQALCSDGKCLEIDR----FCDG 116
Query: 5670 IQDCSDGFDEKNCASLD-RQCKPNEWMCDSGQCIDSGRLCDASVDCVDGSDEWVEICSLS 5494
DCS+ DE NC+S D CD+ +C RL C D S
Sbjct: 117 AWDCSN--DELNCSSNDTATASAPTSACDALKCSYDCRLTSEGARCFCAKD--------S 166
Query: 5493 EPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSSTRNSCDQT 5314
+P NG++ C+ +C CDQ
Sbjct: 167 QP--------------NGSV--------CEDFDEC----------------QIEGLCDQM 188
Query: 5313 WNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKANCSHFCIDRRDVGHQCFCAPGYI 5134
C+ G CSC GY TC S F V +
Sbjct: 189 --CKNQPGAYQCSCTTGY---VRQGNTCTAVNLPKDEPTSLFFTTFNKVKKVSISNRTSV 243
Query: 5133 LSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLTNGVALD-YDVKSDLVY 4957
L+ N N+T+E E L R++ + + L+ + L+ Y V +
Sbjct: 244 LAGN---FPTNETVEEEYLKQPNPRIRAMEMVHRNRTFCLARIDGKSLLECYSVDNTSHS 300
Query: 4956 WTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCD 4777
W D PN +++ I +DW+ N YY D+ + I VC
Sbjct: 301 WVMPRPD----------LFPNLEDIVD---------IRLDWVSGNWYYLDQQREIIFVCS 341
Query: 4776 MRGRFNRILLKG-TPLNDPRAIVLDPLQALVFWTDWGA-SAHIGRMNMDGSNEQVILQDR 4603
+ I+++ + + PR + LDP + +F++ WG+ I R +DG+N I+ ++
Sbjct: 342 PQMVHCAIIVEALSEVLRPRRMALDPTKGFLFFSKWGSGDVSIERSLLDGTNRTSIVLNK 401
Query: 4602 TIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGS-----KRRMVLRGSVRHIFALAVFE 4438
I P +A+D Q +Y+ D H D + NYDGS KR + + ++AL VFE
Sbjct: 402 IIT-PLDIALDLVMQHVYWVDTHLDTVQRVNYDGSGRWFPKRSTQFLFNFQMLYALDVFE 460
Query: 4437 DYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCS- 4261
+Y + W N +I ++ TG R ++ P VH + HPC
Sbjct: 461 RTIYLASWQNGSIVALNGTTGEARVIV-------PNAPHAVHLHVFHRQKQPEVAHPCRI 513
Query: 4260 QPARCDNLCIPANTPDLTTSSDNFTCMCAQGFRSEGRS-CVSECKPNDFVCTKT 4102
Q CD LCIP + CMC+ G+R + +S CV +P + K+
Sbjct: 514 QNGGCDQLCIPVWKKIGVAIAQ---CMCSPGYRLKTKSQCVLIKRPTFLLYAKS 564
Score = 147 bits (371), Expect = 3e-33
Identities = 174/687 (25%), Positives = 261/687 (37%), Gaps = 70/687 (10%)
Frame = -1
Query: 3519 GSDEKGCKKECAIVCDNSCVHADDLCDGKKKCNDG-----SDEDEEACVIKQLLEKENRK 3355
G+ C+ +C +C N+ V KC DG S E + + L+
Sbjct: 828 GNGRNACEIDCPGICLNTPVAVASC-----KCEDGQVLSLSSEGKPVACVPFDLQHSLAS 882
Query: 3354 CGG----------------FACDGIVDCEDGSDEKGCP----DLECHLASN--------- 3262
C + CDG DCEDGSDE+ P D C L N
Sbjct: 883 CNNSTHFLCRNKIDCIEIKYTCDGDRDCEDGSDEETTPDGPCDPNCDLERNFKCDEQRCI 942
Query: 3261 -KSLICDGTIDCSSGKDEN--NCHNNG-ESNFFQC--SMQTIKEWQVCDGRWDCA--DGL 3106
+S +CDG++DC DE+ NC N +FFQC S + I VCD DC D
Sbjct: 943 SRSHVCDGSVDCIDESDEDYINCPNKTCSEHFFQCEVSHRCIPNTWVCDRHLDCGPNDSS 1002
Query: 3105 DE------SPEM------CASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDENP 2962
DE PE C + C + C QC+ V T LC+G DC DG+DE
Sbjct: 1003 DEPEHCHKCPEFECKNSACVPFEFLCDGVDNCGVTNQCIKV-TQLCNGRTDCPDGTDEGF 1061
Query: 2961 IHCKDMCKGKYRCTNGRCIDVSARXXXXXXXXXXXXXXXXGA----ECHHFGVCAQKCWM 2794
+ +C C++ C + C ++G C+Q C
Sbjct: 1062 RCAEKLCDAPNDCSHA-CHNAPEGLICSCPAHLFLQPNGRDCGHDHACDNWGTCSQICTK 1120
Query: 2793 AFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQVSVLRPVFNI 2614
A H RC C GY D+ C + ++ NR ++ ++ + + V R +
Sbjct: 1121 AGTH-YRCGCVEGYT-LMYDKFTCRS-NNGDSPYVIFSNRQEILGVDLNTLGV-RSFYTS 1176
Query: 2613 KMNLIPGGIDFGY-----DVFRTTLM----YTVGIGNSRVDIRSKKWSDGLIGSWGEEES 2461
N I +DF Y +F + +M Y + N + GL S
Sbjct: 1177 LRNTI--ALDFLYRNESVQIFWSDVMDDKIYRGTLRNDTLSNVEAVVQSGL--------S 1226
Query: 2460 TAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAV 2281
TA + D++ N+Y+ +S+ I VAK + RTL+ ++A+
Sbjct: 1227 TAEGLAVDWIGMNIYWIDSNLD----------QIEVAKTNGSFRRTLVAGDMVNPRAIAL 1276
Query: 2280 DPIKRLIFWTT-SAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSN 2104
DP++ ++FWT PR+ + G+ GS P + LD+
Sbjct: 1277 DPMEGVLFWTDWEEGSPRLERCTMAGENRTVIKYVGSDGG---------WPNGIALDYIP 1327
Query: 2103 ERLYWIDVLKRTIETVSFDGRDRRTVRKFE-LGDTPVTMDVLGGYIYLIT-RQGSIHRMH 1930
R+YWID +I T+++DG+D V K + + P ++ V Y+Y R S+ R +
Sbjct: 1328 RRVYWIDARSDSIHTITYDGQDHHLVIKDQGVLAHPFSITVFDNYVYWTDWRTYSVIRAN 1387
Query: 1929 KFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDKN 1750
K+ G +QK + IQI H+ Q NPC D N
Sbjct: 1388 KWNGTDVNVIQKTQSQPFGIQI------LHSSRQPNTQPNPC--------------ADNN 1427
Query: 1749 GILIPKCLCGPGRFFEVSTKKCMQLRE 1669
G CL G E + M+L E
Sbjct: 1428 GGCSHLCLLSVGSRHECACPHVMRLHE 1454
Score = 112 bits (281), Expect = 9e-23
Identities = 84/301 (27%), Positives = 142/301 (46%), Gaps = 27/301 (8%)
Frame = -1
Query: 5217 SCPKAN-------CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVY--G 5065
SC K N C H CI H C CA GY S+ + R I + ++VY G
Sbjct: 1704 SCQKRNDKSAGTGCEHLCIPVSAQSHVCRCAIGY-RSDPRNPWR---CIGLDDILVYSVG 1759
Query: 5064 HRLKLFTIDGHAKAT----------LLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGIT 4915
H+LK + ++T L ++ ++D+DV D VY D ++ IT
Sbjct: 1760 HQLKGIALSSSDESTGSLRNRESLGPLQQISLATSIDFDVAHDYVYIADT----DRGSIT 1815
Query: 4914 SMSNQPNTYRVINSLPTKGIDG--------IAVDWLGRNIYYTDRNHDAIAVCDMRGRFN 4759
+ + VI S + +DG IA+DW+ NIY+TD+ + I V + G
Sbjct: 1816 RIKRDGSAREVIISNFEQVVDGSTLDWLGGIAIDWVAENIYWTDQKRNLIEVARLNGTLR 1875
Query: 4758 RILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNAL 4579
++ + + P+ + +DP+Q +F+ G IGRM +DGS +++ + + L
Sbjct: 1876 YVV--ASDVESPQLLAIDPIQGYLFYVTRGT---IGRMGLDGSGNFILVNRSSAI--SDL 1928
Query: 4578 AVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTI 4399
A+D Q +Y+ + D I +YDG+ +R++L G+ + +L +F D +YW+D +
Sbjct: 1929 ALDLDNQVVYWCETSTDTIWKVDYDGNLKRLLLNGTSHNPKSLDLFGDSIYWADSRGNIY 1988
Query: 4398 E 4396
E
Sbjct: 1989 E 1989
Score = 103 bits (258), Expect = 4e-20
Identities = 99/334 (29%), Positives = 131/334 (38%), Gaps = 16/334 (4%)
Frame = -1
Query: 6036 EKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDG---EDEHQCETECDSKGGNATF 5866
+K C A C CE C+ ++ C G D +C + S ++ F
Sbjct: 2339 DKECSADPCQVMNGFCEDV--CL-IDAAGKVECHCTQGVLAADGQRCIPKSVSNCSSSEF 2395
Query: 5865 RCTNHRCIPMAWRCDGTDDCMDNAKSLGSDE-VDCAAGRTSFHVPSRCADETCVVACELT 5689
CTN CIP CDG +C+D GSDE V A R RC + C+ +
Sbjct: 2396 SCTNGNCIPFHLTCDGVKNCLD-----GSDELVTFCAHRPCPDGFFRCNNARCIPKNQ-- 2448
Query: 5688 AVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASVDCVDGSDEWVE 5509
C+ IQ+C DG DE C+ + + C GQCI CD DC D SDE
Sbjct: 2449 --QCNHIQNCGDGSDEVGCSCNN----ATHFRCTDGQCIVKSMRCDYEPDCKDVSDE--- 2499
Query: 5508 ICSLSEPPRRGCPSGW-SCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQ-CDNPQGNCSST 5335
+ P R C G+ +C T GC CDG DC DEQ C C
Sbjct: 2500 ---IGCPVMRNCTEGFVNCA---NTTGCYMPTWRCDGENDCWDNSDEQDCPTAIPTCPED 2553
Query: 5334 RNSC------DQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLR--SPSCPKANCSHFCID 5179
+ C Q+W C + C+ G LS D+ C++ P+ K + CI
Sbjct: 2554 KFLCANGRCIPQSWRCDDE---DDCTDATGGGLSS-DELACVKHCKPNQFKCTNTSECIS 2609
Query: 5178 R--RDVGHQCFCAPGYILSENQKDCRRNDTIEAE 5083
+ GH CA G S+ C R D E E
Sbjct: 2610 NSWQCDGHP-DCADG---SDEGDHCSRRDCPETE 2639
Score = 99.0 bits (245), Expect = 1e-18
Identities = 62/191 (32%), Positives = 82/191 (42%), Gaps = 3/191 (1%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNC-GNGLCIPEQKVCNRINDCANFADESNCTCNENEFRCQSG 6397
D D + C+ C F C + CI + C+ NDC + +DE +C C E E+RC +G
Sbjct: 3493 DHSDEENCNV-TCSAEQFKCKSHPACISNKFKCDGDNDCIDESDEEDCECQEGEYRCNNG 3551
Query: 6396 ACIPSKARCNHMQDCNDASDEIG--CPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDG 6223
CI S C+ + DC D SDE+G C C+ CA + CI S CD
Sbjct: 3552 KCILSSWVCDGIDDCLDNSDEMGEYCKEHGCN-------KRAFRCANRN-CIRKSLMCDN 3603
Query: 6222 TNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADG 6043
+DC D SDEK C + F C + C+ +CD P C D
Sbjct: 3604 KDDCGDNSDEKSALC------------HKCPPNS-FRCNSDSKCIDIALRCDQTPHCLDE 3650
Query: 6042 SDEKNCDAKKC 6010
SDE C C
Sbjct: 3651 SDEIGCIKTGC 3661
Score = 92.8 bits (229), Expect = 1e-16
Identities = 59/201 (29%), Positives = 86/201 (42%), Gaps = 27/201 (13%)
Frame = -1
Query: 3858 CTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCE-ITSCKPDFFACFNGTAISKCIP 3682
C+++QF C KCIP CD DC DGSDE+ C+ +C F C T ++CIP
Sbjct: 3 CSQSQFTCVMDGKCIPALWRCDTSADCSDGSDEVGCDKAHACNEGMFHC---TVSNRCIP 59
Query: 3681 KEFYCDGEDDC---------PEGQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQCDGTLD 3529
++ CDG+ DC ++P C +C Q C+ GKC+ R CDG D
Sbjct: 60 HDWTCDGDVDCGLVEKYDMVDVSDEDPQLCRAHTKCLPTQALCSDGKCLEIDRFCDGAWD 119
Query: 3528 CRDGSDEKGCKK----------------ECAIVCDNSCVHADDLCDGKKKCNDGSDEDEE 3397
C +DE C +C+ C + A C + N ED +
Sbjct: 120 C--SNDELNCSSNDTATASAPTSACDALKCSYDCRLTSEGARCFCAKDSQPNGSVCEDFD 177
Query: 3396 ACVIKQLLEKE-NRKCGGFAC 3337
C I+ L ++ + G + C
Sbjct: 178 ECQIEGLCDQMCKNQPGAYQC 198
Score = 92.4 bits (228), Expect = 1e-16
Identities = 133/576 (23%), Positives = 207/576 (35%), Gaps = 50/576 (8%)
Frame = -1
Query: 3249 CDGTIDCSSGKDENNCHNNGESN--FFQCSMQT--IKEWQVCDGRWDCA--------DGL 3106
CD + DCS G DE C N F C++ I CDG DC D
Sbjct: 23 CDTSADCSDGSDEVGCDKAHACNEGMFHCTVSNRCIPHDWTCDGDVDCGLVEKYDMVDVS 82
Query: 3105 DESPEMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFD----------GSDENPIH 2956
DE P++C + C D K CL++ CDG DC + + P
Sbjct: 83 DEDPQLCRAHTKCLPTQALCSDGK-CLEIDR-FCDGAWDCSNDELNCSSNDTATASAPTS 140
Query: 2955 CKDMCKGKYRCTNGRCIDVSARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTA 2776
D K Y C R AR EC G+C Q C
Sbjct: 141 ACDALKCSYDC---RLTSEGARCFCAKDSQPNGSVCEDFDECQIEGLCDQMCKNQPG-AY 196
Query: 2775 RCHCAPGYARTKNDENECE-PLSKSAEMFITNGNRLHLMSLENSQVSVLRPVFNIKMNLI 2599
+C C GY R N P + +F T N++ +S+ N + SVL F +
Sbjct: 197 QCSCTTGYVRQGNTCTAVNLPKDEPTSLFFTTFNKVKKVSISN-RTSVLAGNFPTNETVE 255
Query: 2598 ------PGGIDFGYDVFRTTLMYTVGIGNSR-------VDIRSKKWSDGLIGSWGEEEST 2458
P ++ + + + + VD S W + E
Sbjct: 256 EEYLKQPNPRIRAMEMVHRNRTFCLARIDGKSLLECYSVDNTSHSWVMPRPDLFPNLEDI 315
Query: 2457 AGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTI---NSL 2287
I D++ N Y+ D+Q I + +IV + + +
Sbjct: 316 VD-IRLDWVSGNWYY-----------LDQQREIIFVCSPQMVHCAIIVEALSEVLRPRRM 363
Query: 2286 AVDPIKRLIFWTT----SAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMV 2119
A+DP K +F++ + R L LDG ++V I P +
Sbjct: 364 ALDPTKGFLFFSKWGSGDVSIERSL---LDGTN-----------RTSIVLNKIITPLDIA 409
Query: 2118 LDFSNERLYWIDVLKRTIETVSFDGRDR----RTVRKFELGDTPVTMDVLGGYIYLITRQ 1951
LD + +YW+D T++ V++DG R R+ + +DV IYL + Q
Sbjct: 410 LDLVMQHVYWVDTHLDTVQRVNYDGSGRWFPKRSTQFLFNFQMLYALDVFERTIYLASWQ 469
Query: 1950 -GSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKH-TVSHITHQKNPCQSDYCPSNT 1777
GSI ++ TG+ V + + V H K V+H PC+ +
Sbjct: 470 NGSIVALNGTTGEARVIVPNAPHA---VHLHVFHRQKQPEVAH------PCRIQNGGCDQ 520
Query: 1776 VCVPDQDKNGILIPKCLCGPGRFFEVSTK-KCMQLR 1672
+C+P K G+ I +C+C PG + + TK +C+ ++
Sbjct: 521 LCIPVWKKIGVAIAQCMCSPG--YRLKTKSQCVLIK 554
Score = 89.7 bits (221), Expect = 8e-16
Identities = 73/269 (27%), Positives = 96/269 (35%), Gaps = 26/269 (9%)
Frame = -1
Query: 6525 YFNCGNGL-CIPEQKVCNRINDCANFADES---------NCTCNENEFRCQSGACIPSKA 6376
+F C N + CI + C+ DC + +DE NC N F+C CI
Sbjct: 888 HFLCRNKIDCIEIKYTCDGDRDCEDGSDEETTPDGPCDPNCDLERN-FKCDEQRCISRSH 946
Query: 6375 RCNHMQDCNDASDE--IGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDGTNDC--Y 6208
C+ DC D SDE I CP + CS C + +CI +W CD DC
Sbjct: 947 VCDGSVDCIDESDEDYINCPNKTCS-------EHFFQCEVSHRCIPNTWVCDRHLDCGPN 999
Query: 6207 DGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADGSDEKN 6028
D SDE P C +F C C+P + CDG +C
Sbjct: 1000 DSSDE----------------PEHCHKCPEFEC-KNSACVPFEFLCDGVDNCG------- 1035
Query: 6027 CDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDE------------HQCETECDSK 5884
+ +CI + Q C+GR DCPDG DE + C C +
Sbjct: 1036 --------------VTNQCIKVTQLCNGRTDCPDGTDEGFRCAEKLCDAPNDCSHACHNA 1081
Query: 5883 GGNATFRCTNHRCIPMAWRCDGTDDCMDN 5797
C H + R G D DN
Sbjct: 1082 PEGLICSCPAHLFLQPNGRDCGHDHACDN 1110
Score = 89.7 bits (221), Expect = 8e-16
Identities = 66/216 (30%), Positives = 93/216 (42%), Gaps = 22/216 (10%)
Frame = -1
Query: 6129 AKTQFACLATRTCMPKHWQCDGQPDCADGSDEKNCD-AKKCTSFEFSCESSKKCIPLEQK 5953
+++QF C+ C+P W+CD DC+DGSDE CD A C F C S +CIP +
Sbjct: 4 SQSQFTCVMDGKCIPALWRCDTSADCSDGSDEVGCDKAHACNEGMFHCTVSNRCIPHDWT 63
Query: 5952 CDGRRDC--------PDGEDEHQCETECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDN 5797
CDG DC D DE +K C++ +C+ + CDG DC ++
Sbjct: 64 CDGDVDCGLVEKYDMVDVSDEDPQLCRAHTKCLPTQALCSDGKCLEIDRFCDGAWDCSND 123
Query: 5796 AKSLGSDEVDCAAGRTSFHVPSRCADETCVVACELTA--VLCDGIQD-------CSDGFD 5644
+ S++ A+ T S C C C LT+ C +D C D FD
Sbjct: 124 ELNCSSNDTATASAPT-----SACDALKCSYDCRLTSEGARCFCAKDSQPNGSVCED-FD 177
Query: 5643 EKNCASL-DRQCK--PNEWMCD-SGQCIDSGRLCDA 5548
E L D+ CK P + C + + G C A
Sbjct: 178 ECQIEGLCDQMCKNQPGAYQCSCTTGYVRQGNTCTA 213
Score = 89.4 bits (220), Expect = 1e-15
Identities = 70/220 (31%), Positives = 97/220 (43%), Gaps = 28/220 (12%)
Frame = -1
Query: 6432 TCNENEFRC-QSGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTS 6256
TC++++F C G CIP+ RC+ DC+D SDE+GC A NE G+ +C ++
Sbjct: 2 TCSQSQFTCVMDGKCIPALWRCDTSADCSDGSDEVGCD--KAHACNE----GMFHCTVSN 55
Query: 6255 QCIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRT------ 6094
+CI W CDG DC G EK +D S P+ C A T+ CL T+
Sbjct: 56 RCIPHDWTCDGDVDC--GLVEK-----YDMVDVSDEDPQLCRAHTK--CLPTQALCSDGK 106
Query: 6093 CMPKHWQCDGQPDCADGSDEKN---------------CDAKKC------TSFEFSCESSK 5977
C+ CDG DC+ +DE N CDA KC TS C +K
Sbjct: 107 CLEIDRFCDGAWDCS--NDELNCSSNDTATASAPTSACDALKCSYDCRLTSEGARCFCAK 164
Query: 5976 KCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNATFRCT 5857
P C+ +C + E C+ C ++ G CT
Sbjct: 165 DSQPNGSVCEDFDEC---QIEGLCDQMCKNQPGAYQCSCT 201
Score = 81.6 bits (200), Expect = 2e-13
Identities = 83/358 (23%), Positives = 144/358 (40%), Gaps = 7/358 (1%)
Frame = -1
Query: 5199 CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKAT 5020
CSH C+ H+C C L E+++ C N+ I +++ + L H
Sbjct: 1430 CSHLCLLSVGSRHECACPHVMRLHEDRRQCVPNEEILLFVVLTEIRGVDL-QQPAHYTIP 1488
Query: 5019 LLSNLTNGV---ALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDG 4849
+S+ T V LDYD+ + +YW D+ N+ + ++ P I G
Sbjct: 1489 TISHQTQVVQPAVLDYDISAARLYWNDI--QLNEIKSSGLATGP--IETILDTDISNSLG 1544
Query: 4848 IAVDWLGRNIYYTDRN--HDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTD 4675
AVDW+ + +Y++ N H I V ++ G F + G L + +LV +
Sbjct: 1545 FAVDWISKLLYFSTGNETHSRIMVSNLNGEFVTEIADG----------LSVVNSLVVYPT 1594
Query: 4674 WGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSK 4495
++ H ++LA+D RLY+ ++ I + K
Sbjct: 1595 SNSTFHP---------------------IDSLALDFETNRLYYISSNAGEINYYDIGSGK 1633
Query: 4494 RRMVL--RGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFK 4321
VL I + ++ D +Y+ D H+ I R +K N V +++ +
Sbjct: 1634 IIQVLAPHEDNHPISTITIYRDSIYYDDNHDGRIMRCNKNLCQN-PVSVRNNTSGLNAIR 1692
Query: 4320 IVHPSLQSMGSLKTARHPCSQPARCDNLCIPANTPDLTTSSDNFTCMCAQGFRSEGRS 4147
+ HP QS + R+ S C++LCIP S+ + C CA G+RS+ R+
Sbjct: 1693 MYHPGAQSGTNSCQKRNDKSAGTGCEHLCIP-------VSAQSHVCRCAIGYRSDPRN 1743
Score = 77.4 bits (189), Expect = 4e-12
Identities = 64/184 (34%), Positives = 82/184 (43%), Gaps = 26/184 (14%)
Frame = -1
Query: 6522 FNCGNGLCIPEQKVCNRINDCANFADES--NC---TCNENEFRCQ-SGACIPSKARCNHM 6361
F C CI VC+ DC + +DE NC TC+E+ F+C+ S CIP+ C+
Sbjct: 934 FKCDEQRCISRSHVCDGSVDCIDESDEDYINCPNKTCSEHFFQCEVSHRCIPNTWVCDRH 993
Query: 6360 QDC--NDASDEIG----CPFRNCSALN----EFGMTGLINCATTSQCIHPSWKCDGTNDC 6211
DC ND+SDE CP C EF G+ NC T+QCI + C+G DC
Sbjct: 994 LDCGPNDSSDEPEHCHKCPEFECKNSACVPFEFLCDGVDNCGVTNQCIKVTQLCNGRTDC 1053
Query: 6210 YDGSD------EKDCFVEFDATGGSVSAPR----SCDAKTQFACLATRTCMPKHWQCDGQ 6061
DG+D EK C D + +AP SC A F R C H CD
Sbjct: 1054 PDGTDEGFRCAEKLCDAPNDCSHACHNAPEGLICSCPAHL-FLQPNGRDCGHDH-ACDNW 1111
Query: 6060 PDCA 6049
C+
Sbjct: 1112 GTCS 1115
Score = 72.4 bits (176), Expect = 1e-10
Identities = 156/731 (21%), Positives = 256/731 (34%), Gaps = 40/731 (5%)
Frame = -1
Query: 2820 GVCAQKC---WMAFNHT-ARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLE 2653
G C Q C W A+C C+PGY R K +++C + + + N +
Sbjct: 516 GGCDQLCIPVWKKIGVAIAQCMCSPGY-RLKT-KSQCVLIKRPTFLLYAKSNPAMIRGFA 573
Query: 2652 ---NSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVG-IGNSRVDIRSKKWSDGLI 2485
SQ +++ P+ ++ + I F Y V + ++ G I I ++K
Sbjct: 574 VGIKSQEAIV-PITDLGPH-----ITFDYHVEDQLIFFSHGVIDKPSFRIEAQKLDGTQR 627
Query: 2484 GSWGEEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNST 2305
E + I+YD++ NN+++T+S + I V K R ++
Sbjct: 628 ELLLESPGSCDGISYDWLGNNIFWTDSDRNH----------ISVIKLGPKRMRYTVLRQL 677
Query: 2304 GTINSLAVDPIKRLIFWTT-SAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPT 2128
S+ VDP + ++W++ S P RI A ++G QP S ER I PT
Sbjct: 678 YAPKSIVVDPKQGWMYWSSWSVPSGRIDRAWMNG---TQPELLVSSK-----ERPIEWPT 729
Query: 2127 SMVLDFSNERLYWIDVLKRTIETVSFDGRDR------RTVRKFELGDTPVTMDVLGGYIY 1966
+ +D +RLYW D IE+++ DG +R R+ +F PV + V +Y
Sbjct: 730 GLSIDMIQKRLYWCDARLSFIESINLDGSNRVLLFDGRSQNQF-----PVALAVHRQLLY 784
Query: 1965 LITRQGSIHRMHKFTGKTNKYVQKIREVSPRI--QIRVAHPA-------KHTVSHITHQK 1813
F +++K+ P + I + P + + + +
Sbjct: 785 -------------FADNVKGHIEKLNLSDPHLLETITIEKPQVLGLKIFDNLTQYGGNGR 831
Query: 1812 NPCQSDYCPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTK----KCM--QLREKDQEAS 1651
N C+ D CP + P + + C C G+ +S++ C+ L+ +
Sbjct: 832 NACEID-CPGICLNTP------VAVASCKCEDGQVLSLSSEGKPVACVPFDLQHSLASCN 884
Query: 1650 QCGDYFCYNNAGCSPQK-TCVCPPGFYGRQCEINECSETCWNG---ETCAVQEFGSTTNV 1483
+ C N C K TC R CE ET +G C ++ N
Sbjct: 885 NSTHFLCRNKIDCIEIKYTC-----DGDRDCEDGSDEETTPDGPCDPNCDLER-----NF 934
Query: 1482 VCHCPSNYTQSSCATNVCEGV--CGPRGSCKTVPCPKDEPHCRSYSF-CECDKGWTGPHC 1312
C + + ++VC+G C + CP C + F CE
Sbjct: 935 KC----DEQRCISRSHVCDGSVDCIDESDEDYINCPNKT--CSEHFFQCEVSH------- 981
Query: 1311 RHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQNCVGHECLNGGFCSYANSN 1132
R + VC H G + P C C EC N +
Sbjct: 982 RCIPNTWVCDRHLDCGPNDSSDEP-------------EHCHKCPEFECKNSACVPFEFLC 1028
Query: 1131 RSLPHCICPSGFTGDHCE-EYLC--KDACPFGSKCTYDITKPMDPITCSCEQNAAAHNTD 961
+ +C G T + LC + CP G+ + C + D
Sbjct: 1029 DGVDNC----GVTNQCIKVTQLCNGRTDCPDGTDEGF-----------RCAEKLCDAPND 1073
Query: 960 CSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSKCTITNG 781
CS C P G P + + G C CD++ T + CT G
Sbjct: 1074 CSHACHNAPE-----GLICSCPAH-----LFLQPNGRDCGHDHACDNWGTCSQICT-KAG 1122
Query: 780 THFECDCKPGF 748
TH+ C C G+
Sbjct: 1123 THYRCGCVEGY 1133
Score = 57.8 bits (138), Expect = 4e-06
Identities = 58/206 (28%), Positives = 78/206 (37%), Gaps = 27/206 (13%)
Frame = -1
Query: 3999 CIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCEN-FECTEAQFKCGDKK 3823
C QF C + C+ A CD DCS G DE C+ C E F C
Sbjct: 3 CSQSQFTCVMDGK-----CIPALWRCDTSADCSDGSDE--VGCDKAHACNEGMFHCTVSN 55
Query: 3822 KCIPLTSVCDKEKDCD--------DGSDE---LNCEITSCKPDFFACFNGTAISKCIPKE 3676
+CIP CD + DC D SDE L T C P C +G KC+ +
Sbjct: 56 RCIPHDWTCDGDVDCGLVEKYDMVDVSDEDPQLCRAHTKCLPTQALCSDG----KCLEID 111
Query: 3675 FYCDGEDDCPEGQ-----------DEPDSCFGIGECTHE-QFQCTSGKCI-PKRRQCDGT 3535
+CDG DC + P S +C+++ + +C K Q +G+
Sbjct: 112 RFCDGAWDCSNDELNCSSNDTATASAPTSACDALKCSYDCRLTSEGARCFCAKDSQPNGS 171
Query: 3534 LDCRDGSDEKGCKKECAI--VCDNSC 3463
+ C D EC I +CD C
Sbjct: 172 V-CEDFD-------ECQIEGLCDQMC 189
Score = 57.0 bits (136), Expect = 6e-06
Identities = 58/187 (31%), Positives = 75/187 (40%), Gaps = 16/187 (8%)
Frame = -1
Query: 6537 CRPGYFNCG-NGLCIPEQKVCNRINDCANFADESNC----TCNENEFRCQ-SGACIPSKA 6376
C F C +G CIP C+ DC++ +DE C CNE F C S CIP
Sbjct: 3 CSQSQFTCVMDGKCIPALWRCDTSADCSDGSDEVGCDKAHACNEGMFHCTVSNRCIPHDW 62
Query: 6375 RCNHMQDCN--------DASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDGT 6220
C+ DC D SDE + C A + T + + +C+ CDG
Sbjct: 63 TCDGDVDCGLVEKYDMVDVSDE---DPQLCRAHTKCLPTQAL--CSDGKCLEIDRFCDGA 117
Query: 6219 NDCYDGSDEKDCFVEFDATGGSVSAPRS-CDA-KTQFACLATRTCMPKHWQCDGQPDCAD 6046
DC +DE +C AT SAP S CDA K + C T D QP+ +
Sbjct: 118 WDC--SNDELNCSSNDTAT---ASAPTSACDALKCSYDCRLTSEGARCFCAKDSQPNGSV 172
Query: 6045 GSDEKNC 6025
D C
Sbjct: 173 CEDFDEC 179
Score = 55.8 bits (133), Expect = 1e-05
Identities = 86/395 (21%), Positives = 146/395 (36%), Gaps = 18/395 (4%)
Frame = -1
Query: 2814 CAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQVSV 2635
C C + C CA GY + C L + + G++L ++L +S S
Sbjct: 1717 CEHLCIPVSAQSHVCRCAIGYRSDPRNPWRCIGLDDI--LVYSVGHQLKGIALSSSDEST 1774
Query: 2634 --------LRPVFNIKMNLIPGGIDFGY--------DVFRTTLMYTVGIGNSRVDIRS-- 2509
L P+ I + IDF D R ++ G++R I S
Sbjct: 1775 GSLRNRESLGPLQQISLAT---SIDFDVAHDYVYIADTDRGSITRIKRDGSAREVIISNF 1831
Query: 2508 KKWSDGLIGSWGEEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTST 2329
++ DG W G I D++ N+Y+T D++ N+ + +
Sbjct: 1832 EQVVDGSTLDW------LGGIAIDWVAENIYWT-----------DQKRNLIEVARLNGTL 1874
Query: 2328 RTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVE 2149
R ++ + + LA+DPI+ +F+ T + R+ LDG + LV
Sbjct: 1875 RYVVASDVESPQLLAIDPIQGYLFYVTRGTIGRM---GLDGSG-----------NFILVN 1920
Query: 2148 RNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYI 1969
R+ + + LD N+ +YW + TI V +DG +R + P ++D+ G I
Sbjct: 1921 RSS-AISDLALDLDNQVVYWCETSTDTIWKVDYDGNLKRLLLN-GTSHNPKSLDLFGDSI 1978
Query: 1968 YLITRQGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYC 1789
Y +G+I+ + V + EVS I+V K + ++ N + C
Sbjct: 1979 YWADSRGNIYEAGLSNIFNYRSVVEALEVSSLKDIKVFSSRKQSKTNACGVSNGGCQELC 2038
Query: 1788 PSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKC 1684
N P C C G+ K C
Sbjct: 2039 LFNGT-----------HPICACSHGKISSADLKTC 2062
Score = 51.6 bits (122), Expect = 3e-04
Identities = 40/137 (29%), Positives = 50/137 (36%), Gaps = 9/137 (6%)
Frame = -1
Query: 4134 CKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNA 3955
C + F C KCI + WR G C G F C T N
Sbjct: 3 CSQSQFTCVMDGKCIPALWRCDTSADCSDGSDEV----GCDKAHACNEGMFHC--TVSN- 55
Query: 3954 TAQCLYASKLCDGVKDCS--------GGDDEEPAFCE-NFECTEAQFKCGDKKKCIPLTS 3802
+C+ CDG DC DE+P C + +C Q C D KC+ +
Sbjct: 56 --RCIPHDWTCDGDVDCGLVEKYDMVDVSDEDPQLCRAHTKCLPTQALCSD-GKCLEIDR 112
Query: 3801 VCDKEKDCDDGSDELNC 3751
CD DC +DELNC
Sbjct: 113 FCDGAWDC--SNDELNC 127
>gi|28573304|ref|NP_788284.1| CG33087-PC [Drosophila melanogaster]
gi|23240381|gb|AAF59114.3| CG33087-PC [Drosophila melanogaster]
Length = 4699
Score = 863 bits (2230), Expect = 0.0
Identities = 644/2096 (30%), Positives = 910/2096 (42%), Gaps = 140/2096 (6%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESN--CTCNENE------ 6415
DE YC R C +F C N CIP++ C+ C + +DE+ C C +
Sbjct: 2607 DEFRSYCIFRQCPETHFMCQNHRCIPKEHKCDGEQQCGDGSDETPLLCKCQSEDIDMHPS 2666
Query: 6414 ----------FRCQSGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCA 6265
FRC SG CIP K C+ ++DC D SDE C C + MT ++C
Sbjct: 2667 NNNTKEMPDMFRCGSGECIPRKFLCDSLKDCRDFSDEKMCAPIPCEKND---MT-FVHCG 2722
Query: 6264 TTSQCIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMP 6085
++ CI P W+CDG DC DG+DE DC + SCD QF C A+ C+
Sbjct: 2723 NSTICIMPRWRCDGDPDCPDGTDELDC---------ANHTSLSCDPG-QFRC-ASGNCIA 2771
Query: 6084 KHWQCDGQPDCADGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQC 5905
W CDG+ DC DGSDE NC + C +F+C+ K CIP +CDG+ DC DG DE
Sbjct: 2772 GSWHCDGEKDCPDGSDEINCRTE-CRHNQFACD--KTCIPASWQCDGKSDCEDGSDEGP- 2827
Query: 5904 ETECDSKGGNA-TFRC-TNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPS 5731
+C ++ F+C ++ RCIP W CDG DC GS++ G + H+P
Sbjct: 2828 --QCPNRPCRPHLFQCKSSGRCIPQKWVCDGEKDCPSGLGDEGSEDEGPQCGGVA-HIPD 2884
Query: 5730 ------RCADETCVVACELTAVLCDGIQDCSDGFDE-KNC--ASLDRQCKPNEWM--CDS 5584
C C+ + +CDG +DC G DE + C A C M C
Sbjct: 2885 CPPPAHLCTSGLCIDS----HYVCDGDEDCPGGDDEYEGCVPAFQPHSCPGGSLMHQCQD 2940
Query: 5583 GQCIDSGRLCDASVDCVDGSDEWVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCD 5404
G CI + CD DC DGSDE +C+ + RGC NG C+ LCD
Sbjct: 2941 GLCIFKNQTCDGKPDCGDGSDETSSLCAHT----RGCNGTDDFRCKNGA--CIHADLLCD 2994
Query: 5403 GRRDCMSGIDEQCDNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLR 5224
R DC DE+ N N + C+ C+ C C GY + P C
Sbjct: 2995 RRNDCADFSDEELCNV--NECLIPDICEH--ECEDKVVGYQCHCRPGYKVLPKSPHLCTD 3050
Query: 5223 SPSCPKAN-CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLF 5047
C + CS CI+ ++C CA GY L ++ C+ + E++ + ++
Sbjct: 3051 IDECDEQQPCSQTCINTYG-SYKCLCAKGYALVDHHT-CKATSNVSMELIFSNRYYIRQV 3108
Query: 5046 TIDGHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLP 4867
+ G+ + L++ L+N VALDYD S +YW+DV I + N + ++
Sbjct: 3109 DMTGNG-SILINELSNAVALDYDWDSQCLYWSDVT--STVGTIKRYCPKENKTQTLHQAM 3165
Query: 4866 TKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALV 4687
K DG+AVDW+ +N+Y+ D+ D I V + G++ ++L+ L +PR I L P Q +
Sbjct: 3166 LKNPDGLAVDWVAKNLYWCDKGLDTIEVSQLDGKYRKVLINEY-LREPRGIALHPYQQHI 3224
Query: 4686 FWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNY 4507
FW+DWG S HIG+ MDGSN ++I++D + WPNAL + Q+L++GDA D I+ +
Sbjct: 3225 FWSDWGDSPHIGKAGMDGSNPKMIIRD-GLGWPNALTISFETQQLFWGDAREDTISVSDL 3283
Query: 4506 DGSKRRMVLRGSV------RHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDK 4345
DG+ R++L S+ HIFA+AV+E ++YWSDW +IE G N LI
Sbjct: 3284 DGNHTRLLLARSINPLLNLHHIFAIAVWEGHIYWSDWETKSIEYCSIFNGQNCTTLI-TT 3342
Query: 4344 QYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDNLCIPANTPDLTTSSDNFTCMCAQGF 4165
+RPM ++ HP Q + +PC A C LC+ L+ + CMC F
Sbjct: 3343 IHRPMDLRVFHPYRQQQ---PMSGNPC-LAANCSTLCV------LSPEEPYYKCMCPTNF 3392
Query: 4164 --RSEGRSCVSECKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIA 3991
+GR+C + C F C TYKCI +WR CPPF C
Sbjct: 3393 ILADDGRTCRANCTAAHFECVNTYKCIPFYWRCDTQDDCGDGSDE----PETCPPFHCEP 3448
Query: 3990 GQF---------------------------------------VCGRTAQNATAQCLYASK 3928
GQ+ CG TA N++A C+ K
Sbjct: 3449 GQYQCANKKCTHPSNLCDGINQCGDGSDELNCDKFTCFDNHMKCGATA-NSSAFCVDNVK 3507
Query: 3927 LCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCE 3748
CDGVKDC GG+DE + C C + QF+CG+ +C+P VCD + DC D SDE NC+
Sbjct: 3508 RCDGVKDCPGGEDE--SACTPLVCKKDQFQCGN-NRCMPFVWVCDGDIDCPDKSDEANCD 3564
Query: 3747 ITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGI-GECTHEQFQCTSG 3571
SC P+ F C +G +CIP + CD + DCP G+DEP SCF C F+C +
Sbjct: 3565 NVSCGPNDFQCDSG----RCIPLAWRCDDDHDCPNGEDEPASCFSSKATCDPTYFKCNNS 3620
Query: 3570 KCIPKRRQCDGTLDCRDGSDEKGCK----KECAIVC-DNSCVHADDLCDGKKKCNDGSDE 3406
KCIP R +CD DC DGSDE C+ E C C+ + CDG+ C+D SDE
Sbjct: 3621 KCIPGRWRCDYENDCGDGSDELNCQMRNCSESEFRCGTGKCIKHNYRCDGEIHCDDNSDE 3680
Query: 3405 DEEACVIKQLLEKENR-KCGGF--------ACDGIVDCEDGSDEKGCPDLECHLASNKSL 3253
+ + KEN+ KC F CDG DC DGSDE C CH
Sbjct: 3681 -----INCNITCKENQFKCAAFNTCINKQYKCDGDDDCPDGSDEVNC---TCH------- 3725
Query: 3252 ICDGTIDCSSGKDENNCHNNGESNFFQCSMQTIKEWQVCDGRWDCADGLDESPEMCASRK 3073
D +C N +C M K CDG DC DG DES E CA K
Sbjct: 3726 -----------SDHFSCGNG------KCIMSRWK----CDGWDDCLDGSDESLETCA--K 3762
Query: 3072 ARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCK---GKYRCTNGRCID 2902
C + + C+ ++ALCDGI DC + DE+ C + K +++C N CI
Sbjct: 3763 THCHANAFKCRNQLCVR-NSALCDGINDCGENEDESDAVCAALPKCRHDQFQCENDDCIS 3821
Query: 2901 VSARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENEC 2722
+ R FG C+Q C C CA GY + C
Sbjct: 3822 KAFRCDGQYNCVDGSDEMNCQPPVCGFGSCSQICIEKKAGHYNCKCADGYHKGPEKNATC 3881
Query: 2721 EPLSKSAEMFITNGNRLHLM---SLENSQV-------SVLRPVFNIKM---NLIPGGIDF 2581
+ + + + E + V S+ VF+I + + + ID
Sbjct: 3882 LASGPDQILLLASEQEFRFILPAKQEGTTVVGFFQTDSLKIDVFDILIRPKDTLLFWIDS 3941
Query: 2580 GYDVFRTTLMYTVGIGNSRVDIRS--KKWSDGLIGSWGEEESTAGLITYDFMHNNVYFTE 2407
+ T + T + + V +R K+ + I + +S A D++ VY +
Sbjct: 3942 HHGKVHTMKIATPHVEGTGVRVRRDLKELTAFNIPELDDPKSLA----VDWISQRVYIID 3997
Query: 2406 SSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRI 2227
S N+ + D + Y++ +V++ + ++P R++ W+T I
Sbjct: 3998 -SRHNQILATDIEGKKYIS----------LVSTGMNPTDIVLEPESRIMIWSTLE--NGI 4044
Query: 2226 LSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFD 2047
L A+LDG K+LVER++ P S+ +D+ RLYW D K TIET +
Sbjct: 4045 LVASLDG-----------SNKKSLVERDVGWPISLSMDYPTGRLYWADYRKGTIETCRLN 4093
Query: 2046 GRDRRTVRKFELGDTPVTMDVLGGYIYLITRQGSIHRMHKFTGKTNKYVQKIREVSPRIQ 1867
G+DR VR+F + P +DV Y+Y+ SI +M+KF Y+ K S
Sbjct: 4094 GKDRNVVRRFGNREKPQKIDVFEDYLYIKLYDQSIIKMNKFGNDNGTYLLKGYRSS---D 4150
Query: 1866 IRVAHPAKHTVSHITHQKNPCQSDYCPSN-TVCVPDQDKNGILIPKCLCGPGRFFEVSTK 1690
I + HP K + NPC D C S+ +C+ + + + C C G
Sbjct: 4151 IGILHPMKQN----RNISNPCAKDPCKSSRALCILSSESS--VGYSCKCAEGYVMTDDGV 4204
Query: 1689 KCMQLREKDQEASQCGDYFCYNNAGCSPQKTCVCPPGFYGRQCEINECSETCWNGETCAV 1510
D QC C C+C P F G CE CS C N C+V
Sbjct: 4205 CKAHADIPDYCPLQCNLGTC---KIVDHVPKCICQPQFEGELCEHYRCSGYCQNYGVCSV 4261
Query: 1509 QEF--GS--TTNVVCHCPSNYTQSSCATNV--CEGVCGPRGSCKTVPCPKDEPHCRSYSF 1348
GS + C C + ++ + C T++ C+ C GSC +
Sbjct: 4262 APALPGSQEPPPLKCTCTAGWSGARCETSMPACQSRCHNGGSCLISETEGMK-------- 4313
Query: 1347 CECDKGWTGPHCRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQ--NCVGH 1174
C C K +TG C H + C +GG C +C C DG TG RC+ C
Sbjct: 4314 CSCPKMFTGEQCEHCRNLT-----CENGGICRETLTGTPQCECPDGFTGKRCEIDECADF 4368
Query: 1173 ECLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDACPFGSKCT-----YDITKPMD 1009
C NGG C S + C CPSG+ G+HCE C+D C G C+ T P
Sbjct: 4369 -CKNGGSC--VISTKGQRQCKCPSGYFGEHCESNSCRDFCRNGGTCSERGGRLSCTCPPR 4425
Query: 1008 PITCSCEQ-----NAAAHNTDCSPICQKQP---NWCHNGGRCLDTPGYPGKCKCLPRFAG 853
I SCE ++ H D + + + P C N G C G C C ++ G
Sbjct: 4426 YIGESCESDLCKTSSPPHFCDNTKVPTRDPCTLMICQNAGTCHIIKGV-ALCNCTDQWNG 4484
Query: 852 PRCDVPV----QCDDYCTNNSKCTITNGTHFECDCKPGFKGLRCEQETKC--SECS 703
C +PV C YC N C + C C ++G CE C EC+
Sbjct: 4485 DLCTLPVTDDNPCARYCANGGVCHLDEYRLPHCSCIGEWQGNACEMPPHCVGGECN 4540
Score = 368 bits (944), Expect = 1e-99
Identities = 446/1808 (24%), Positives = 670/1808 (36%), Gaps = 270/1808 (14%)
Frame = -1
Query: 5256 LSPYDKKTCLRSPSCPKAN--CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAE 5083
L Y K S C +N C C+ C CA + S+ C + E
Sbjct: 2202 LKIYSKHLQRGSNPCAHSNGACEQLCLFN-GTSAVCACAHSRLASDGYS-C---EPYENF 2256
Query: 5082 ILMVYGHRLKLFTIDGHAKAT----LLSN---LTNGVALDYDVKSDLVYWTDVAHDGNKA 4924
+L Y ++ + HA ++SN + N +A+ Y+ + LVY++DV +
Sbjct: 2257 LLFSYRSNIESIHMTDHADKNWPVQMISNTSLMRNVIAITYNYEEQLVYYSDV----QLS 2312
Query: 4923 GITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMR-----GRFN 4759
I + +RV+ + ++G+A D + +++T N+ I ++R N
Sbjct: 2313 TINQVHFNGTGHRVLLEQQQR-VEGLAYDIVNEQLFWTSNNNATIRSVELRHLSEHADQN 2371
Query: 4758 RILLKGTPL----NDPRAIVLDPLQALVFWTDWG-ASAHIGRMNMDGSNEQVILQDRTIR 4594
++ +K + PR I ++P +++WT+W S I R + G +VI++ I+
Sbjct: 2372 QVHVKKVLSLREDDKPRGIAVEPCLGMIYWTNWNEGSPCIQRSYLTGYGTEVIIKT-DIK 2430
Query: 4593 WPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDW 4414
PNAL +D Q+LY+ DA D I NYDGS R ++ + +H FA+AV+ D ++W+DW
Sbjct: 2431 MPNALTLDLEQQKLYWADARLDKIERTNYDGSNRVVLAHSTPKHAFAMAVYGDLLFWTDW 2490
Query: 4413 HNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCS-QPARCDNL 4237
H + R +K TGT+ + +++ RPMG V + S+ + C +C+++
Sbjct: 2491 VLHAVVRANKYTGTD-VLFLREHVTRPMGIVAVQNT-----SINCDANQCKILNGQCEDV 2544
Query: 4236 CIPANTPDLTTSSDNFTCMCAQG-FRSEGRSCVS----------------ECKPNDFVCT 4108
CI S TC C QG +GR C++ EC P + C
Sbjct: 2545 CI-------LNKSGQATCHCTQGVLAPDGRRCIAPVNTSCGLSQYNCHSGECIPLELTCD 2597
Query: 4107 KTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASK 3928
C Y + CP F+C QN +C+
Sbjct: 2598 NVTHCADG-----------SDEFRSYCIFRQCP-----ETHFMC----QN--HRCIPKEH 2635
Query: 3927 LCDGVKDCSGGDDEEPAFCE-------------NFECTEAQFKCGDKKKCIPLTSVCDKE 3787
CDG + C G DE P C+ N + F+CG +CIP +CD
Sbjct: 2636 KCDGEQQCGDGSDETPLLCKCQSEDIDMHPSNNNTKEMPDMFRCG-SGECIPRKFLCDSL 2694
Query: 3786 KDCDDGSDELNCEITSCKPD---FFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCF 3616
KDC D SDE C C+ + F C N T CI + CDG+ DCP+G DE D
Sbjct: 2695 KDCRDFSDEKMCAPIPCEKNDMTFVHCGNSTI---CIMPRWRCDGDPDCPDGTDELDCAN 2751
Query: 3615 GIG-ECTHEQFQCTSGKCIPKRRQCDGTLDCRDGSDEKGCKKEC---AIVCDNSCVHADD 3448
C QF+C SG CI CDG DC DGSDE C+ EC CD +C+ A
Sbjct: 2752 HTSLSCDPGQFRCASGNCIAGSWHCDGEKDCPDGSDEINCRTECRHNQFACDKTCIPASW 2811
Query: 3447 LCDGKKKCNDGSDEDEEA----CVIKQLLEKENRKC--GGFACDGIVDC-----EDGSDE 3301
CDGK C DGSDE + C K + +C + CDG DC ++GS++
Sbjct: 2812 QCDGKSDCEDGSDEGPQCPNRPCRPHLFQCKSSGRCIPQKWVCDGEKDCPSGLGDEGSED 2871
Query: 3300 KG-----------CPDLECHLAS-----NKSLICDGTIDCSSGKDE----------NNCH 3199
+G CP HL + + +CDG DC G DE ++C
Sbjct: 2872 EGPQCGGVAHIPDCPP-PAHLCTSGLCIDSHYVCDGDEDCPGGDDEYEGCVPAFQPHSC- 2929
Query: 3198 NNGESNFFQC-SMQTIKEWQVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCLD 3022
G S QC I + Q CDG+ DC DG DE+ +CA + + C+
Sbjct: 2930 -PGGSLMHQCQDGLCIFKNQTCDGKPDCGDGSDETSSLCAHTRGCNGTDDFRCKNGACIH 2988
Query: 3021 VSTALCDGIRDCFDGSDEN---------PIHCKDMCKGK---YRCTNGRCIDVSARXXXX 2878
+ LCD DC D SDE P C+ C+ K Y+C V +
Sbjct: 2989 -ADLLCDRRNDCADFSDEELCNVNECLIPDICEHECEDKVVGYQCHCRPGYKVLPKSPHL 3047
Query: 2877 XXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAE 2698
EC C+Q C + + +C CA GYA D + C+ S +
Sbjct: 3048 CTDID---------ECDEQQPCSQTCINTYG-SYKCLCAKGYALV--DHHTCKATS-NVS 3094
Query: 2697 MFITNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYD-----VFRTTLMYTVGIG 2533
M + NR ++ ++ + +I +N + + YD ++ + + TVG
Sbjct: 3095 MELIFSNRYYIRQVDMTGNG------SILINELSNAVALDYDWDSQCLYWSDVTSTVGTI 3148
Query: 2532 NSRVDIRSK---------KWSDGLIGSWGEEESTAGLITYDFMHNNVYFTESSEQNRGVL 2380
+K K DGL W + N+Y+ +
Sbjct: 3149 KRYCPKENKTQTLHQAMLKNPDGLAVDW--------------VAKNLYWCDKGLD----- 3189
Query: 2379 FDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKP 2200
I V++ + LI +A+ P ++ IFW+ P I A +D
Sbjct: 3190 -----TIEVSQLDGKYRKVLINEYLREPRGIALHPYQQHIFWSDWGDSPHIGKAGMD--- 3241
Query: 2199 IAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRK 2020
GS P K ++ + P ++ + F ++L+W D + TI DG R +
Sbjct: 3242 -------GSNP-KMIIRDGLGWPNALTISFETQQLFWGDAREDTISVSDLDGNHTRLLLA 3293
Query: 2019 FELGDT-----PVTMDVLGGYIYLIT-RQGSIHRMHKFTGKTNKYVQKIREVSPRIQIRV 1858
+ + V G+IY SI F G+ I + + +RV
Sbjct: 3294 RSINPLLNLHHIFAIAVWEGHIYWSDWETKSIEYCSIFNGQ--NCTTLITTIHRPMDLRV 3351
Query: 1857 AHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIP------------KCLCGPG 1714
HP + NPC + C + V P++ + P + C
Sbjct: 3352 FHPYR---QQQPMSGNPCLAANCSTLCVLSPEEPYYKCMCPTNFILADDGRTCRANCTAA 3408
Query: 1713 RFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCSPQKTCV---CPPGFY---GRQCE-- 1558
F V+T KC+ + CGD G +TC C PG Y ++C
Sbjct: 3409 HFECVNTYKCIPFYWRCDTQDDCGD-------GSDEPETCPPFHCEPGQYQCANKKCTHP 3461
Query: 1557 ------INECSE----------TCWNGETCAVQEFGSTTNV-------------VCHCPS 1465
IN+C + TC++ + G+T N V CP
Sbjct: 3462 SNLCDGINQCGDGSDELNCDKFTCFDNH----MKCGATANSSAFCVDNVKRCDGVKDCPG 3517
Query: 1464 NYTQSSCATNVCEGVCGPRGSCKTVP----------CP--KDEPHCRSYSF----CECDK 1333
+S+C VC+ G+ + +P CP DE +C + S +CD
Sbjct: 3518 GEDESACTPLVCKKDQFQCGNNRCMPFVWVCDGDIDCPDKSDEANCDNVSCGPNDFQCDS 3577
Query: 1332 GWTGPHCRHKADAKVC------YGHCFSGGA-CDGEGPLNLRCS---------------- 1222
G P D C CFS A CD P +C+
Sbjct: 3578 GRCIPLAWRCDDDHDCPNGEDEPASCFSSKATCD---PTYFKCNNSKCIPGRWRCDYEND 3634
Query: 1221 CGDGLTGNRCQ--NCVGHE--CLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDAC 1054
CGDG CQ NC E C G + HC D+ +E C C
Sbjct: 3635 CGDGSDELNCQMRNCSESEFRCGTGKCIKHNYRCDGEIHC-------DDNSDEINCNITC 3687
Query: 1053 PFGS--------------KCTYDITKP--MDPITCSC-EQNAAAHNTDCSPICQKQPNW- 928
KC D P D + C+C + + N C K W
Sbjct: 3688 KENQFKCAAFNTCINKQYKCDGDDDCPDGSDEVNCTCHSDHFSCGNGKCIMSRWKCDGWD 3747
Query: 927 -CHNGG-----RCLDTPGYPGKCKCLPRFA---GPRCDVPVQC-------DDYCTNNSKC 796
C +G C T + KC + CD C D C KC
Sbjct: 3748 DCLDGSDESLETCAKTHCHANAFKCRNQLCVRNSALCDGINDCGENEDESDAVCAALPKC 3807
Query: 795 TITNGTHFEC---DCKPGFKGLRCEQETKCSECSNEAK--------------CIKKPSGT 667
F+C DC K RC+ + C + S+E CI+K +G
Sbjct: 3808 ---RHDQFQCENDDCIS--KAFRCDGQYNCVDGSDEMNCQPPVCGFGSCSQICIEKKAGH 3862
Query: 666 VICQCPQG 643
C+C G
Sbjct: 3863 YNCKCADG 3870
Score = 321 bits (823), Expect = 1e-85
Identities = 239/751 (31%), Positives = 335/751 (43%), Gaps = 32/751 (4%)
Frame = -1
Query: 6270 CATTSQCIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTC 6091
C +T QC+ CDG DC DG DE D G +CD F C C
Sbjct: 933 CRSTRQCLDTKDMCDGFEDCEDGIDESS-----DPKGPC--NVNTCDKTHNFVC--NGRC 983
Query: 6090 MPKHWQCDGQPDCADGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDC-PDGEDE 5914
+ C P C+DG+D+ NC C S EF+C S +CI L DG DC PD + +
Sbjct: 984 YQRSLLCSTIPYCSDGTDQANCHQNTCNSNEFTCHKSGRCIQLTWVNDGVVDCGPDDDSD 1043
Query: 5913 HQCETECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVP 5734
ET SK F C N RC A CDG D+C +NA DE++C + H
Sbjct: 1044 ETSETIFASK--CPEFDCNNGRCRQFADVCDGIDNCGNNA-----DEMECE--QECEHGE 1094
Query: 5733 SRCADETCVVACELTAVLCDGIQDCSDGFDEKNCASLDR------------QCKPNEWMC 5590
C + C +CDGI DC D DE NC +C P E+ C
Sbjct: 1095 KYCRP----IGCYGEMHMCDGIHDCLDFSDEANCNQTKSDNHPVTEWKELGECAPLEFAC 1150
Query: 5589 -DSGQCIDSGRLCDASVDCVDGSDEWVEICSLSEPPRRGCPSGWSCLLTNGTIG----CL 5425
+CI CD C D +DE+ C+ R C + G C+
Sbjct: 1151 MFPFECIPDFLRCDGISHCFDKTDEF--NCTHINTTRFDMNETVICEHPDRLCGFSKQCV 1208
Query: 5424 QEQQLCDGRRDCMSGIDEQCDNPQGNCSSTRNSCDQTWNCQRHA-----GFESCSCDDGY 5260
QLCDG+ DC DE CD+ C G+ CSC D
Sbjct: 1209 TVDQLCDGKNDCEDTTDE-------GFLCADKLCDRGHECSHRCHNTPEGY-ICSCPDHL 1260
Query: 5259 HLSPYDKKTCLRSPSCPKANCSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEI 5080
+L P K+ ++ CS C + G+ C C G+ L ++ C+ E +
Sbjct: 1261 YLQPNGKRCSMQHACDHWDTCSQVC-ESSGKGYDCRCLDGFDLGFDRFTCKSTAPDEPYV 1319
Query: 5079 LMVYGHRLKLFTIDGHAKATLLSNLTNGVALD--YDVKSDL-VYWTDVAHDGNKAGITSM 4909
+ +K + S+L N +ALD Y+ +S++ +YWTDV D G
Sbjct: 1320 IFTNRQDIKGINLKTLNVGNFYSSLRNIIALDFLYNNESNVEIYWTDVIDDKIYRGHLVG 1379
Query: 4908 SNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLN 4729
+ N VI+S +G+AVDW+G+N+Y+ D N D I V + G F R L+ G +
Sbjct: 1380 ESLRNVEAVIHS-GLSTTEGLAVDWVGKNLYWIDSNLDQIEVAKLNGSFRRTLIAGN-ME 1437
Query: 4728 DPRAIVLDPLQALVFWTDW-GASAHIGRMNMDGSNEQVILQDRTIR--WPNALAVDAPAQ 4558
PRAI LDP + L+FWTDW S I R +M G ++I + WPN L +D +
Sbjct: 1438 SPRAIALDPREGLLFWTDWDDNSPRIERASMSGDGRRMISTSWQLSAGWPNGLTLDYTQK 1497
Query: 4557 RLYFGDAHRDYIASCNYDGSKRRMVLRGS--VRHIFALAVFEDYVYWSDWHNHTIERVHK 4384
R+Y+ DA D I+S YDGS+ +VLR + H FA++VFE+YVYW+DW ++ R +K
Sbjct: 1498 RVYWVDAKSDSISSTMYDGSEHHVVLRNKEILSHPFAISVFENYVYWTDWRTTSVIRANK 1557
Query: 4383 ITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQ-PARCDNLCIPANTPDLT 4207
G++ +VL Q Q +P G +++H S Q R+PC + C +LC L
Sbjct: 1558 WNGSDVQVL-QRTQSQPFGIQVLHSSRQPWD-----RNPCGENNGGCSHLC-------LL 1604
Query: 4206 TSSDNFTCMCAQGFRSEGRSCVSECKPNDFV 4114
+ F C C R + + C PN+ V
Sbjct: 1605 SGRGTFKCECPHVMRLDPAN-ERNCVPNEQV 1634
Score = 204 bits (518), Expect = 3e-50
Identities = 123/320 (38%), Positives = 157/320 (48%), Gaps = 6/320 (1%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADE------SNCTCNENEF 6412
D D C C P F C +G CIP C+ +DC N DE S TC+ F
Sbjct: 3556 DKSDEANCDNVSCGPNDFQCDSGRCIPLAWRCDDDHDCPNGEDEPASCFSSKATCDPTYF 3615
Query: 6411 RCQSGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWK 6232
+C + CIP + RC++ DC D SDE+ C RNCS +EF C T +CI +++
Sbjct: 3616 KCNNSKCIPGRWRCDYENDCGDGSDELNCQMRNCSE-SEF------RCG-TGKCIKHNYR 3667
Query: 6231 CDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDC 6052
CDG C D SDE +C + +C + QF C A TC+ K ++CDG DC
Sbjct: 3668 CDGEIHCDDNSDEINCNI-------------TC-KENQFKCAAFNTCINKQYKCDGDDDC 3713
Query: 6051 ADGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNA 5872
DGSDE NC C S FSC + KCI KCDG DC DG DE ET +
Sbjct: 3714 PDGSDEVNC---TCHSDHFSC-GNGKCIMSRWKCDGWDDCLDGSDE-SLETCAKTHCHAN 3768
Query: 5871 TFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACEL 5692
F+C N C+ + CDG +DC +N SD V CAA H +C ++ C+
Sbjct: 3769 AFKCRNQLCVRNSALCDGINDCGENEDE--SDAV-CAALPKCRHDQFQCENDDCI----S 3821
Query: 5691 TAVLCDGIQDCSDGFDEKNC 5632
A CDG +C DG DE NC
Sbjct: 3822 KAFRCDGQYNCVDGSDEMNC 3841
Score = 182 bits (463), Expect = 7e-44
Identities = 205/813 (25%), Positives = 313/813 (38%), Gaps = 112/813 (13%)
Frame = -1
Query: 5205 ANCSHFCIDRRDVGH---QCFCAPGYILSENQKDCRRNDTIEAEILMVYGH----RLKLF 5047
A C+ C+ + G +C C GY L NQ C + + +VY R+
Sbjct: 544 AGCNQICVPQWTKGFASAKCMCTAGYKL-HNQTTCLLS---ALDKFLVYSDKHLARISGI 599
Query: 5046 TIDGHAKATL------------LSNLTNGVALDYDVKSDLVYWTDVAHDGNK-------- 4927
+D L + N++ +A+D +V+ V++ VA G
Sbjct: 600 PLDTEQVQQLEQIGEQPDVMVPVYNVSKTLAIDVNVRGKAVFYV-VADSGASPFGNGEPS 658
Query: 4926 AGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILL 4747
I S S + R++ + K + +A DW+ ++Y+T +H + V +R +++L
Sbjct: 659 CSIRSQSLNGSVSRLL-AQGLKRVHAVAFDWINDHLYWT--SHKKMQVAPLRN-LSKVLT 714
Query: 4746 KGTPLNDPRAIVLDPLQALVFWTDW---GASAHIGRMNMDGSNEQVILQDRT---IRWPN 4585
T D ++ LDP L++W+ W A I MDG++++++ + + ++WP
Sbjct: 715 FNTDC-DAMSLELDPTTGLLYWSQWESQSCEAGIYSSWMDGTHKELLAKGTSSMPMQWPR 773
Query: 4584 ALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNH 4405
+L VD + LY+ D I DG+ R ++ + H +++ +YW+D N
Sbjct: 774 SLDVDRRTKELYWCDIRLSTIELMRLDGTGREVLFKSDQFHPYSIVQNNGLIYWADNKNS 833
Query: 4404 TIERVH----KITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDNL 4237
TI R H ++ T + + R +I + Q + +A C+Q ++C +
Sbjct: 834 TILRFHAHQANLSSTFSSTVHLQRTGRAADLRIFDIASQPLPQTPSA---CAQ-SKCPGM 889
Query: 4236 CIPANTPDLTTSSDNFTCMCAQGF--RSEGRSCVSECKP--------NDFVCTKTYKCIS 4087
C+ NTP C C GF G C+ + P + ++C T +C+
Sbjct: 890 CL--NTP------KGAICRCPDGFTLNGTGSHCIPQLAPSPIRPNCTSGYMCRSTRQCLD 941
Query: 4086 SWWRXXXXXXXXXXXXXGYFVEGVCPPFPC-IAGQFVCGRTAQNATAQCLYASKLCDGVK 3910
+ +G C C FVC +C S LC +
Sbjct: 942 TKDMCDGFEDCEDGIDESSDPKGPCNVNTCDKTHNFVC-------NGRCYQRSLLCSTIP 994
Query: 3909 DCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDC--DDGSDELNCEITSC 3736
CS G D+ A C C +F C +CI LT V D DC DD SDE + I +
Sbjct: 995 YCSDGTDQ--ANCHQNTCNSNEFTCHKSGRCIQLTWVNDGVVDCGPDDDSDETSETIFAS 1052
Query: 3735 KPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIPK 3556
K F C NG +C CDG D+C DE + EC H + C C +
Sbjct: 1053 KCPEFDCNNG----RCRQFADVCDGIDNCGNNADEMEC---EQECEHGEKYCRPIGCYGE 1105
Query: 3555 RRQCDGTLDCRDGSDEKGCKK--------------------ECAIVCDNSCVHADDLCDG 3436
CDG DC D SDE C + E A + C+ CDG
Sbjct: 1106 MHMCDGIHDCLDFSDEANCNQTKSDNHPVTEWKELGECAPLEFACMFPFECIPDFLRCDG 1165
Query: 3435 KKKCNDGSDE-----------DEEACVIKQLLEKENRKCG--------GFACDGIVDCED 3313
C D +DE D VI E +R CG CDG DCED
Sbjct: 1166 ISHCFDKTDEFNCTHINTTRFDMNETVI---CEHPDRLCGFSKQCVTVDQLCDGKNDCED 1222
Query: 3312 GSDEKGCPDLECHLASNKSLICDGTIDCSSGKDENNCHNNGES-------------NFFQ 3172
+DE L ++K +CD +CS + CHN E N +
Sbjct: 1223 TTDEG-------FLCADK--LCDRGHECS-----HRCHNTPEGYICSCPDHLYLQPNGKR 1268
Query: 3171 CSMQ-TIKEW----QVCDGRWD-----CADGLD 3103
CSMQ W QVC+ C DG D
Sbjct: 1269 CSMQHACDHWDTCSQVCESSGKGYDCRCLDGFD 1301
Score = 155 bits (391), Expect = 2e-35
Identities = 185/753 (24%), Positives = 293/753 (38%), Gaps = 56/753 (7%)
Frame = -1
Query: 3858 CTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELN-----CEITSC-KPDFFACFNGTAI 3697
CT + C ++C+ +CD +DC+DG DE + C + +C K F C NG
Sbjct: 927 CTSG-YMCRSTRQCLDTKDMCDGFEDCEDGIDESSDPKGPCNVNTCDKTHNFVC-NG--- 981
Query: 3696 SKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQC-TSGKCIPKRRQCDGTLDCR- 3523
+C + C C +G D+ + C C +F C SG+CI DG +DC
Sbjct: 982 -RCYQRSLLCSTIPYCSDGTDQAN-CHQ-NTCNSNEFTCHKSGRCIQLTWVNDGVVDCGP 1038
Query: 3522 -DGSDEKG----CKKECAIVCDNS-CVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKEN 3361
D SDE K C+N C D+CDG C + +DE E
Sbjct: 1039 DDDSDETSETIFASKCPEFDCNNGRCRQFADVCDGIDNCGNNADEME------------- 1085
Query: 3360 RKCGGFACDGIVDCEDGSDEKGCPDLECHLASNKSLICDGTIDCSSGKDENNCHNNGESN 3181
C+ +CE G EK C + C+ + +CDG DC DE NC+ N
Sbjct: 1086 -------CEQ--ECEHG--EKYCRPIGCY---GEMHMCDGIHDCLDFSDEANCNQTKSDN 1131
Query: 3180 F---------------FQCSM--QTIKEWQVCDGRWDCADGLDESPEMCASRKARCFRIG 3052
F C + I ++ CDG C D DE C F +
Sbjct: 1132 HPVTEWKELGECAPLEFACMFPFECIPDFLRCDGISHCFDKTDEFN--CTHINTTRFDMN 1189
Query: 3051 ----------YCDDKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKGKYRCTNGRCID 2902
C KQC+ V LCDG DC D +DE + +C + C++ RC +
Sbjct: 1190 ETVICEHPDRLCGFSKQCVTVDQ-LCDGKNDCEDTTDEGFLCADKLCDRGHECSH-RCHN 1247
Query: 2901 VSARXXXXXXXXXXXXXXXXGAE----CHHFGVCAQKCWMAFNHTARCHCAPGYARTKND 2734
C H+ C+Q C + C C G+ D
Sbjct: 1248 TPEGYICSCPDHLYLQPNGKRCSMQHACDHWDTCSQVC-ESSGKGYDCRCLDGF-DLGFD 1305
Query: 2733 ENECEPLSKSAEMFITNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTL 2554
C+ + E ++ NR + + ++V ++ N+I +DF Y+
Sbjct: 1306 RFTCKSTAPD-EPYVIFTNRQDIKGINLKTLNV-GNFYSSLRNII--ALDFLYNNESNVE 1361
Query: 2553 MYTVGIGNSRVDIRSKKWSDGLIG-SWGEEE-------STAGLITYDFMHNNVYFTESSE 2398
+Y + I K + L+G S E ST + D++ N+Y+ +S+
Sbjct: 1362 IYWTDV------IDDKIYRGHLVGESLRNVEAVIHSGLSTTEGLAVDWVGKNLYWIDSNL 1415
Query: 2397 QNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTT-SAPVPRILS 2221
I VAK + RTLI + + ++A+DP + L+FWT PRI
Sbjct: 1416 D----------QIEVAKLNGSFRRTLIAGNMESPRAIALDPREGLLFWTDWDDNSPRIER 1465
Query: 2220 ANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGR 2041
A++ G G + + + P + LD++ +R+YW+D +I + +DG
Sbjct: 1466 ASMSG--------DGRRMISTSWQLSAGWPNGLTLDYTQKRVYWVDAKSDSISSTMYDGS 1517
Query: 2040 DRRTV-RKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGKTNKYVQKIREVSPRIQ 1867
+ V R E+ P + V Y+Y R S+ R +K+ G + +Q R S
Sbjct: 1518 EHHVVLRNKEILSHPFAISVFENYVYWTDWRTTSVIRANKWNGSDVQVLQ--RTQSQPFG 1575
Query: 1866 IRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCV 1768
I+V H ++ +NPC + + +C+
Sbjct: 1576 IQVLHSSRQ-----PWDRNPCGENNGGCSHLCL 1603
Score = 139 bits (351), Expect = 7e-31
Identities = 100/328 (30%), Positives = 132/328 (39%), Gaps = 21/328 (6%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC--TCNENEFRCQS 6400
D+ D ++ C PG F C +G CI C+ DC + +DE NC C N+F C
Sbjct: 2745 DELDCANHTSLSCDPGQFRCASGNCIAGSWHCDGEKDCPDGSDEINCRTECRHNQFACDK 2804
Query: 6399 GACIPSKARCNHMQDCNDASDE-IGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDG 6223
CIP+ +C+ DC D SDE CP R C L C ++ +CI W CDG
Sbjct: 2805 -TCIPASWQCDGKSDCEDGSDEGPQCPNRPC-------RPHLFQCKSSGRCIPQKWVCDG 2856
Query: 6222 TNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADG 6043
DC G ++ E GG P D + C+ H+ CDG DC G
Sbjct: 2857 EKDCPSGLGDEGSEDEGPQCGGVAHIP---DCPPPAHLCTSGLCIDSHYVCDGDEDCPGG 2913
Query: 6042 SDE-KNC----DAKKCT--SFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSK 5884
DE + C C S C+ CI Q CDG+ DC DG DE ++
Sbjct: 2914 DDEYEGCVPAFQPHSCPGGSLMHQCQDG-LCIFKNQTCDGKPDCGDGSDE-TSSLCAHTR 2971
Query: 5883 GGNAT--FRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETC 5710
G N T FRC N CI CD +DC D + + +C H C D+
Sbjct: 2972 GCNGTDDFRCKNGACIHADLLCDRRNDCADFSDEELCNVNECLIPDICEH---ECEDKVV 3028
Query: 5709 VVACEL---------TAVLCDGIQDCSD 5653
C + LC I +C +
Sbjct: 3029 GYQCHCRPGYKVLPKSPHLCTDIDECDE 3056
Score = 137 bits (345), Expect = 4e-30
Identities = 142/594 (23%), Positives = 235/594 (38%), Gaps = 25/594 (4%)
Frame = -1
Query: 5868 FRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACELT 5689
F C + CIPM W+CD DC D + C G+ V C
Sbjct: 44 FTCNDGFCIPMRWKCDSKADCPDMSDEGSECAPKCNEGQFRCGVSRHCIPNNW------- 96
Query: 5688 AVLCDGIQDCSDG--FDEKNCASLDR-QCKPNEWMCDSGQCIDSGRLCDASVDCVDGSDE 5518
LCDG DC G DE NC + D +C+ E C +G C++ R CD DC +DE
Sbjct: 97 --LCDGEFDCGKGDISDELNCPNGDTPKCRAFEGQCRNGDCLELSRFCDGRWDC--DNDE 152
Query: 5517 WVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGID-EQCDNPQGNCS 5341
C ++C LT C + + +D ++C P
Sbjct: 153 LQ--CDKQNAACAALNCSFNCKLTPQGARCYCPKDQVPESSNSTRCVDYDECSEP----- 205
Query: 5340 STRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKANCSHFCIDRRDV-- 5167
+CDQ C+ G CSC GY + ++ + P P + + R V
Sbjct: 206 ---GTCDQV--CRNTPGSYECSCVSGYAKTKGNRCRAINVP--PTEPTTLIFLSRDGVQS 258
Query: 5166 ----GHQCFCAPGYILSENQKDCRRNDTIEAEILMV-----YGHRLKLFTIDGHAKATLL 5014
G + PG +N K ++ E L++ + H +++ H TL
Sbjct: 259 VGTNGTEVIGPPG--AKDNDKVTDKDGVGSEEELLLSQPLRFVHAFEVW----HRNRTLC 312
Query: 5013 SNLTNGVALDYD---VKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIA 4843
S L + L V V WT +S + P + +
Sbjct: 313 SLLFSWPELQMRCQRVDDARVNWT--------LPFSSFVS-----------PQQFFTELR 353
Query: 4842 VDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDP-RAIVLDPLQALVFWTDWGA 4666
+DWL N Y + + +C + R++L+ DP ++ LDP + +F+TDW
Sbjct: 354 LDWLSGNWYLVSEDDGLVYLCTNAMTYCRVILQQV---DPLSSLDLDPTKGFMFYTDWTP 410
Query: 4665 SAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRM 4486
S + R +DGSN V++ D+ + P+++ +D + +Y+ D ++D + +Y+G R
Sbjct: 411 S--LSRSLLDGSNRTVLVTDQ-VYHPSSVTLDLANELVYWIDIYKDEVNRVDYEGRNRWT 467
Query: 4485 VLRG-----SVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFK 4321
+ R ++ I A+ VFE+ +Y + W + I + K + + ++Q R +
Sbjct: 468 LKRPLDSPVPLKTIHAVEVFENSIYLAAWMDTAIVALDKF--SLKTHILQSNVSRGANLR 525
Query: 4320 IVHPSLQSMGSLKTARHPC-SQPARCDNLCIPANTPDLTTSSDNFTCMCAQGFR 4162
I H Q HPC A C+ +C+P T ++ CMC G++
Sbjct: 526 IFHRQKQ-----PEVAHPCRDNNAGCNQICVPQWTKGFASAK----CMCTAGYK 570
Score = 135 bits (340), Expect = 1e-29
Identities = 106/390 (27%), Positives = 147/390 (37%), Gaps = 46/390 (11%)
Frame = -1
Query: 1401 CKTVPCPKDEPHCRSYS------FCECDKGWTGPHCRHKADAKVCYGHCFSGGACDGEGP 1240
C PC C S C+C +G+ D VC H C +
Sbjct: 4167 CAKDPCKSSRALCILSSESSVGYSCKCAEGYV------MTDDGVCKAHADIPDYCPLQCN 4220
Query: 1239 LNL--------RCSCGDGLTGNRCQN--CVGHECLNGGFCSYA----NSNRSLP-HCICP 1105
L +C C G C++ C G+ C N G CS A S P C C
Sbjct: 4221 LGTCKIVDHVPKCICQPQFEGELCEHYRCSGY-CQNYGVCSVAPALPGSQEPPPLKCTCT 4279
Query: 1104 SGFTGDHCEEYL--CKDACPFGSKCTYDITKPMDPITCSCEQNAAAHNTDCSPICQKQPN 931
+G++G CE + C+ C G C T+ M CSC + C+ N
Sbjct: 4280 AGWSGARCETSMPACQSRCHNGGSCLISETEGMK---CSCPKMFTGEQ------CEHCRN 4330
Query: 930 W-CHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSKCTITNGTHFECDCKP 754
C NGG C +T +C+C F G RC++ +C D+C N C I+ +C C
Sbjct: 4331 LTCENGGICRETLTGTPQCECPDGFTGKRCEID-ECADFCKNGGSCVISTKGQRQCKCPS 4389
Query: 753 GFKGLRCEQETKCSECSNEAKCIKKPSGTVICQCPQGLGGEYCEK--------------- 619
G+ G CE + C N C ++ G + C CP GE CE
Sbjct: 4390 GYFGEHCESNSCRDFCRNGGTCSER-GGRLSCTCPPRYIGESCESDLCKTSSPPHFCDNT 4448
Query: 618 --ITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCS-----SNACENFCLH 460
T C + C+N G C + C C+ + G LC+ N C +C +
Sbjct: 4449 KVPTRDPCTLMICQNAGTC-----HIIKGVALCNCTDQWNGDLCTLPVTDDNPCARYCAN 4503
Query: 459 DGNCTLDEYFEPQCECYQAFIGDRCQYRIH 370
G C LDEY P C C + G+ C+ H
Sbjct: 4504 GGVCHLDEYRLPHCSCIGEWQGNACEMPPH 4533
Score = 127 bits (320), Expect = 3e-27
Identities = 102/374 (27%), Positives = 170/374 (45%), Gaps = 19/374 (5%)
Frame = -1
Query: 5208 KANCSHFCIDRRDVGHQCFCAPGYILSENQKD--CRRNDTIEAEILMVYGHRL----KLF 5047
+ C C+ + H C CA GY + N R + I I ++ G + + F
Sbjct: 1902 RGGCQQLCLATSSIDHVCRCALGYDVEPNNPTGCVPRAEFIFYSIDVLQGVEMIDPSEQF 1961
Query: 5046 TIDGHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYR--VINS 4873
A + S +++ +DY +D +YW D N+ G S + T R ++ +
Sbjct: 1962 DTPSPALVPI-SRVSSASFIDYLANTDTLYWGD-----NELGSISRVKRDGTQRETILEA 2015
Query: 4872 LPTKG------IDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIV 4711
L G + GIA+DW+ NIY++D + I V + G +++ L P A+
Sbjct: 2016 LNLVGYKQQDWLGGIAIDWVAGNIYWSDTKRNIIEVARLDGSHRYVVVSN--LEKPTALA 2073
Query: 4710 LDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWP-NALAVDAPAQRLYFGDAH 4534
+DPLQ L+F+ HIGR+ +DGS V++ W +L +D A ++Y+ + +
Sbjct: 2074 VDPLQGLLFYV---TQQHIGRVGLDGSQPFVLVNQTRANWAVGSLVLDIEATKVYWCERY 2130
Query: 4533 RDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSD-WHNHTIERVHKITGTNR-KV 4360
D + +YDG+ R +L S+ + ALA DY+YW++ +N I RV + ++ KV
Sbjct: 2131 PDALMKVDYDGNLREQLLNESLNNPVALAKMGDYLYWAENKYNEGIIRVAPLANLSQSKV 2190
Query: 4359 LIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQP-ARCDNLCIPANTPDLTTSSDNFTC 4183
++Q +Q KI LQ +PC+ C+ LC+ T + C
Sbjct: 2191 VLQTEQDAIRDLKIYSKHLQ------RGSNPCAHSNGACEQLCLFNGT--------SAVC 2236
Query: 4182 MCAQG-FRSEGRSC 4144
CA S+G SC
Sbjct: 2237 ACAHSRLASDGYSC 2250
Score = 115 bits (288), Expect = 1e-23
Identities = 99/358 (27%), Positives = 139/358 (38%), Gaps = 75/358 (20%)
Frame = -1
Query: 6552 CSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC---TCNENEFRC-QSGACIP 6385
C+ C + NG C +C+ I C++ D++NC TCN NEF C +SG CI
Sbjct: 966 CNVNTCDKTHNFVCNGRCYQRSLLCSTIPYCSDGTDQANCHQNTCNSNEFTCHKSGRCIQ 1025
Query: 6384 SKARCNHMQDC--NDASDEIG-------CPFRNCS--ALNEFG--MTGLINCATTSQ--- 6253
+ + DC +D SDE CP +C+ +F G+ NC +
Sbjct: 1026 LTWVNDGVVDCGPDDDSDETSETIFASKCPEFDCNNGRCRQFADVCDGIDNCGNNADEME 1085
Query: 6252 ----------------CIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCD--A 6127
C CDG +DC D SDE +C + + V+ + A
Sbjct: 1086 CEQECEHGEKYCRPIGCYGEMHMCDGIHDCLDFSDEANC-NQTKSDNHPVTEWKELGECA 1144
Query: 6126 KTQFACLATRTCMPKHWQCDGQPDCADGSDEKNCDAKKCTSFEFS-----------CESS 5980
+FAC+ C+P +CDG C D +DE NC T F+ + C S
Sbjct: 1145 PLEFACMFPFECIPDFLRCDGISHCFDKTDEFNCTHINTTRFDMNETVICEHPDRLCGFS 1204
Query: 5979 KKCIPLEQKCDGRRDCPDGEDE------------HQCETECDSKGGNATFRCTNH----- 5851
K+C+ ++Q CDG+ DC D DE H+C C + C +H
Sbjct: 1205 KQCVTVDQLCDGKNDCEDTTDEGFLCADKLCDRGHECSHRCHNTPEGYICSCPDHLYLQP 1264
Query: 5850 ---RCIPMAWRCDGTDDCMDNAKSLGSDEVDCAA------GRTSFHVPSRCADETCVV 5704
RC M CD D C +S G DC G F S DE V+
Sbjct: 1265 NGKRC-SMQHACDHWDTCSQVCESSGKG-YDCRCLDGFDLGFDRFTCKSTAPDEPYVI 1320
Score = 115 bits (288), Expect = 1e-23
Identities = 162/665 (24%), Positives = 250/665 (37%), Gaps = 33/665 (4%)
Frame = -1
Query: 3609 GECTHEQFQCTSGKCIPKRRQCDGTLDCRDGSDEKGCKKECAIVCDNSCVHADDLCDGKK 3430
G C F C G CIP R +CD DC D SDE ECA
Sbjct: 37 GPCPASYFTCNDGFCIPMRWKCDSKADCPDMSDE---GSECA-----------------P 76
Query: 3429 KCNDGSDEDEEACVIKQLLEKENRKCGGFACDGIVDCEDG--SDEKGCPDLECHLASNKS 3256
KCN+G + C + + N + CDG DC G SDE CP+
Sbjct: 77 KCNEG----QFRCGVSRHCIPNN-----WLCDGEFDCGKGDISDELNCPN---------- 117
Query: 3255 LICDGTIDCSSGKDENNCHNNGESNFFQCSMQTIKEWQVCDGRWDCADGLDESPEMCASR 3076
T C + E C N ++ + CDGRWDC D C +
Sbjct: 118 ---GDTPKCRA--FEGQCRNG----------DCLELSRFCDGRWDC----DNDELQCDKQ 158
Query: 3075 KARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKGKYRCTNGRCIDVS 2896
A C + C G R C+ D+ P + RC+D
Sbjct: 159 NAACAAL-------NCSFNCKLTPQGAR-CYCPKDQVP----------ESSNSTRCVDYD 200
Query: 2895 ARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECE- 2719
EC G C Q C + C C GYA+TK N C
Sbjct: 201 --------------------ECSEPGTCDQVC-RNTPGSYECSCVSGYAKTKG--NRCRA 237
Query: 2718 ----PLSKSAEMFI---------TNGNRL--HLMSLENSQVSVLRPVFNIKMNLIPGGID 2584
P + +F+ TNG + + +N +V+ V + + L+ +
Sbjct: 238 INVPPTEPTTLIFLSRDGVQSVGTNGTEVIGPPGAKDNDKVTDKDGVGSEEELLLSQPLR 297
Query: 2583 F--GYDVF-RTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGLITYDFMHNNVYF 2413
F ++V+ R + ++ + +R ++ D + +W S+ F+ +F
Sbjct: 298 FVHAFEVWHRNRTLCSLLFSWPELQMRCQRVDDARV-NWTLPFSS-------FVSPQQFF 349
Query: 2412 TESS----EQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTS 2245
TE N ++ + +Y+ T R +I+ ++SL +DP K +F+T
Sbjct: 350 TELRLDWLSGNWYLVSEDDGLVYLCTNAMTYCR-VILQQVDPLSSLDLDPTKGFMFYTDW 408
Query: 2244 APVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTI 2065
P + + LDG LV ++ P+S+ LD +NE +YWID+ K +
Sbjct: 409 --TPSLSRSLLDG-----------SNRTVLVTDQVYHPSSVTLDLANELVYWIDIYKDEV 455
Query: 2064 ETVSFDGRDRRTVRKFELGDTPV------TMDVLGGYIYLIT-RQGSIHRMHKFTGKTNK 1906
V ++GR+R T+++ D+PV ++V IYL +I + KF+ KT+
Sbjct: 456 NRVDYEGRNRWTLKR--PLDSPVPLKTIHAVEVFENSIYLAAWMDTAIVALDKFSLKTHI 513
Query: 1905 YVQKIREVSPRIQIRVAHPAKH-TVSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKC 1729
VS +R+ H K V+H PC+ + N +CVP K G KC
Sbjct: 514 LQS---NVSRGANLRIFHRQKQPEVAH------PCRDNNAGCNQICVPQWTK-GFASAKC 563
Query: 1728 LCGPG 1714
+C G
Sbjct: 564 MCTAG 568
Score = 112 bits (279), Expect = 2e-22
Identities = 106/377 (28%), Positives = 135/377 (35%), Gaps = 70/377 (18%)
Frame = -1
Query: 6030 NCDAKKCTSFEFSCES------------------------------------------SK 5977
NCDA +C CE S
Sbjct: 2528 NCDANQCKILNGQCEDVCILNKSGQATCHCTQGVLAPDGRRCIAPVNTSCGLSQYNCHSG 2587
Query: 5976 KCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNAT-FRCTNHRCIPMAWRCDGTDDCMD 5800
+CIPLE CD C DG DE + + C + T F C NHRCIP +CDG C D
Sbjct: 2588 ECIPLELTCDNVTHCADGSDEFR--SYCIFRQCPETHFMCQNHRCIPKEHKCDGEQQCGD 2645
Query: 5799 NAKSLGSDEV----DCAAGRTSFHVPS-----------RCADETCVVACELTAVLCDGIQ 5665
GSDE C + H PS RC C+ LCD ++
Sbjct: 2646 -----GSDETPLLCKCQSEDIDMH-PSNNNTKEMPDMFRCGSGECIP----RKFLCDSLK 2695
Query: 5664 DCSDGFDEKNCASLDRQCKPNEWMC----DSGQCIDSGRLCDASVDCVDGSDE--WVEIC 5503
DC D DEK CA + C+ N+ +S CI CD DC DG+DE
Sbjct: 2696 DCRDFSDEKMCAPI--PCEKNDMTFVHCGNSTICIMPRWRCDGDPDCPDGTDELDCANHT 2753
Query: 5502 SLS-EPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSSTRNS 5326
SLS +P + C SG C+ CDG +DC G DE N + C + +
Sbjct: 2754 SLSCDPGQFRCASG----------NCIAGSWHCDGEKDCPDGSDE--INCRTECRHNQFA 2801
Query: 5325 CDQT-----WNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKANCSHFCIDRRDVGH 5161
CD+T W C + C+DG P CP C + G
Sbjct: 2802 CDKTCIPASWQCDGKS-----DCEDGSD----------EGPQCPNRPCRPHLFQCKSSGR 2846
Query: 5160 QCFCAPGYILSENQKDC 5110
C P + + +KDC
Sbjct: 2847 ---CIPQKWVCDGEKDC 2860
Score = 109 bits (273), Expect = 8e-22
Identities = 76/225 (33%), Positives = 104/225 (45%), Gaps = 3/225 (1%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGN-GLCIPEQKVCNRINDCANFADESNCTCNENEFRCQSG 6397
D+ D C+ C+ F C CI +Q C+ +DC + +DE NCTC+ + F C +G
Sbjct: 3676 DNSDEINCNI-TCKENQFKCAAFNTCINKQYKCDGDDDCPDGSDEVNCTCHSDHFSCGNG 3734
Query: 6396 ACIPSKARCNHMQDCNDASDEI--GCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDG 6223
CI S+ +C+ DC D SDE C +C A N F + C+ S CDG
Sbjct: 3735 KCIMSRWKCDGWDDCLDGSDESLETCAKTHCHA-NAFKCRNQL-------CVRNSALCDG 3786
Query: 6222 TNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADG 6043
NDC + DE D +V A QF C C+ K ++CDGQ +C DG
Sbjct: 3787 INDCGENEDESD----------AVCAALPKCRHDQFQC-ENDDCISKAFRCDGQYNCVDG 3835
Query: 6042 SDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQ 5908
SDE NC C SC S+ CI +K G +C + H+
Sbjct: 3836 SDEMNCQPPVCGF--GSC--SQICI---EKKAGHYNCKCADGYHK 3873
Score = 92.4 bits (228), Expect = 1e-16
Identities = 58/149 (38%), Positives = 74/149 (48%), Gaps = 6/149 (4%)
Frame = -1
Query: 6252 CIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQ 6073
CI WKCD DC D SDE GS AP+ + QF C +R C+P +W
Sbjct: 51 CIPMRWKCDSKADCPDMSDE-----------GSECAPKCNEG--QFRCGVSRHCIPNNWL 97
Query: 6072 CDGQPDCADG--SDEKNC---DAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQ 5908
CDG+ DC G SDE NC D KC +FE C + C+ L + CDGR DC + DE Q
Sbjct: 98 CDGEFDCGKGDISDELNCPNGDTPKCRAFEGQCRNG-DCLELSRFCDGRWDCDN--DELQ 154
Query: 5907 CETECDSKGG-NATFRCTNHRCIPMAWRC 5824
C+ + + N +F C + P RC
Sbjct: 155 CDKQNAACAALNCSFNC---KLTPQGARC 180
Score = 90.5 bits (223), Expect = 5e-16
Identities = 70/263 (26%), Positives = 103/263 (38%), Gaps = 25/263 (9%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC--TCNENEFRCQS 6400
DD D + + F+C NG C VC+ I++C N ADE C C E C+
Sbjct: 1040 DDSDETSETIFASKCPEFDCNNGRCRQFADVCDGIDNCGNNADEMECEQECEHGEKYCRP 1099
Query: 6399 GACIPSKARCNHMQDCNDASDEIGC--------PFRNCSALNEFGMTGLINCATTSQCIH 6244
C C+ + DC D SDE C P L E C +CI
Sbjct: 1100 IGCYGEMHMCDGIHDCLDFSDEANCNQTKSDNHPVTEWKELGECAPLEFA-CMFPFECIP 1158
Query: 6243 PSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDG 6064
+CDG + C+D +DE +C + T ++ C+ + C ++ C+ CDG
Sbjct: 1159 DFLRCDGISHCFDKTDEFNC-THINTTRFDMNETVICEHPDRL-CGFSKQCVTVDQLCDG 1216
Query: 6063 QPDCADGSDE------KNCD-----AKKC----TSFEFSCESSKKCIPLEQKCDGRRDCP 5929
+ DC D +DE K CD + +C + SC P ++C + C
Sbjct: 1217 KNDCEDTTDEGFLCADKLCDRGHECSHRCHNTPEGYICSCPDHLYLQPNGKRCSMQHACD 1276
Query: 5928 DGEDEHQCETECDSKGGNATFRC 5860
+ C C+S G RC
Sbjct: 1277 HWD---TCSQVCESSGKGYDCRC 1296
Score = 85.9 bits (211), Expect = 1e-14
Identities = 58/193 (30%), Positives = 79/193 (40%), Gaps = 11/193 (5%)
Frame = -1
Query: 6093 CMPKHWQCDGQPDCADGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGE-- 5920
C+P W+CD + DC D SDE + A KC +F C S+ CIP CDG DC G+
Sbjct: 51 CIPMRWKCDSKADCPDMSDEGSECAPKCNEGQFRCGVSRHCIPNNWLCDGEFDCGKGDIS 110
Query: 5919 DEHQCETECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFH 5740
DE C K +C N C+ ++ CDG DC ++ CAA SF+
Sbjct: 111 DELNCPNGDTPKCRAFEGQCRNGDCLELSRFCDGRWDCDNDELQCDKQNAACAALNCSFN 170
Query: 5739 VP-----SRCADETCVVACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPN----EWMCD 5587
+RC V + C +CS+ + D+ C+ E C
Sbjct: 171 CKLTPQGARCYCPKDQVPESSNSTRCVDYDECSEP------GTCDQVCRNTPGSYECSCV 224
Query: 5586 SGQCIDSGRLCDA 5548
SG G C A
Sbjct: 225 SGYAKTKGNRCRA 237
Score = 85.9 bits (211), Expect = 1e-14
Identities = 87/377 (23%), Positives = 160/377 (42%), Gaps = 12/377 (3%)
Frame = -1
Query: 5250 PYDKKTCLRSPSCPKANCSHFCIDRRDVGHQCFCAPGYILSE-NQKDCRRNDTIEAEILM 5074
P+D+ C + CSH C+ +C C L N+++C N+ + +++
Sbjct: 1585 PWDRNPCGEN----NGGCSHLCLLSGRGTFKCECPHVMRLDPANERNCVPNEQVLLFVMV 1640
Query: 5073 VYGHRLKLFTIDGHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDG-NKAGITSMSNQP 4897
+ L + H T+ + +D+ V ++W+D+ + + AGI++ +P
Sbjct: 1641 DEIRGIDLHQPNHHTIPTIRQSPRR---IDFLVDESRIFWSDIQQNEISSAGISNGLIEP 1697
Query: 4896 NTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDA-IAVCDMRGRFNRILLKGTPLNDPR 4720
+IN+ K G AVDW+ RN+Y++ I +++G F I+ + LN
Sbjct: 1698 ----IINTNIEKPY-GFAVDWIARNMYFSSGQIKCNILASNLKGEFASIIHE--DLNMVD 1750
Query: 4719 AIVLDPLQALVFW---TDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLY 4549
+IVLDP ++W G+ + + + N+DGS+ +I Q +L +D +QRLY
Sbjct: 1751 SIVLDPANGKMYWIHSASDGSMSQLEQSNLDGSSRSLIYQHENNL--QSLTMDFDSQRLY 1808
Query: 4548 FGDAHRDYIASCNYD---GSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKIT 4378
+ D YD R++++ + I +L V+ +Y+ E + +
Sbjct: 1809 YA---YDNSGIAYYDIPRNETRKVLVASPITSISSLTVYNGTLYFP-------ENIQSVI 1858
Query: 4377 GTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPA---RCDNLCIPANTPDLT 4207
K + Y + K + +T + C++ A C LC L
Sbjct: 1859 MQCEKEACSNMSYLRVNTKSIQSMKMFYADAQTGSNTCAEWAYRGGCQQLC-------LA 1911
Query: 4206 TSSDNFTCMCAQGFRSE 4156
TSS + C CA G+ E
Sbjct: 1912 TSSIDHVCRCALGYDVE 1928
Score = 80.9 bits (198), Expect = 4e-13
Identities = 188/898 (20%), Positives = 315/898 (34%), Gaps = 74/898 (8%)
Frame = -1
Query: 2829 HHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLEN 2650
H G C Q C FN T+ CA ++R +D CEP E F+ R ++ S+
Sbjct: 2218 HSNGACEQLC--LFNGTSAV-CACAHSRLASDGYSCEPY----ENFLLFSYRSNIESIHM 2270
Query: 2649 -------------SQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTL--MYTVGIGNSRVDI 2515
S S++R V I N + + DV +T+ ++ G G+ RV +
Sbjct: 2271 TDHADKNWPVQMISNTSLMRNVIAITYNYEEQLVYYS-DVQLSTINQVHFNGTGH-RVLL 2328
Query: 2514 RSKKWSDGLIGSWGEEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDT 2335
++ +GL YD ++ +++T ++ + R + + + +
Sbjct: 2329 EQQQRVEGL--------------AYDIVNEQLFWTSNNNATIRSVELRHLSEHADQNQVH 2374
Query: 2334 STRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKAL 2155
+ L + +AV+P +I+WT +G P Q + +
Sbjct: 2375 VKKVLSLREDDKPRGIAVEPCLGMIYWTNWN----------EGSPCIQRSYLTGYGTEVI 2424
Query: 2154 VERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGG 1975
++ +I P ++ LD ++LYW D IE ++DG R V M V G
Sbjct: 2425 IKTDIKMPNALTLDLEQQKLYWADARLDKIERTNYDG-SNRVVLAHSTPKHAFAMAVYGD 2483
Query: 1974 YIYLIT-RQGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQS 1798
++ ++ R +K+TG T+ + P + V + + I N C+
Sbjct: 2484 LLFWTDWVLHAVVRANKYTG-TDVLFLREHVTRPMGIVAVQN------TSINCDANQCKI 2536
Query: 1797 DYCPSNTVCVPDQD-------KNGILIP---KCL------CGPGRFFEVSTKKCMQLREK 1666
VC+ ++ G+L P +C+ CG + + + +C+ L
Sbjct: 2537 LNGQCEDVCILNKSGQATCHCTQGVLAPDGRRCIAPVNTSCGLSQ-YNCHSGECIPLELT 2595
Query: 1665 DQEASQCGDYFCYNNAGCSPQKTCVCPPGFYGRQCEINEC---SETCWNGETCAVQEFGS 1495
+ C D + C ++ CP + C+ + C C + C +
Sbjct: 2596 CDNVTHCADGSDEFRSYCIFRQ---CPETHF--MCQNHRCIPKEHKCDGEQQCG--DGSD 2648
Query: 1494 TTNVVCHCPS---------NYTQSSCATNVC-EGVCGPRG-SCKTVPCPKDEPHCRSYSF 1348
T ++C C S N T+ C G C PR C ++ +D + +
Sbjct: 2649 ETPLLCKCQSEDIDMHPSNNNTKEMPDMFRCGSGECIPRKFLCDSLKDCRDFSDEKMCAP 2708
Query: 1347 CECDKG-WTGPHCRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQNCVGHE 1171
C+K T HC ++ +C CDG+ C DG C N
Sbjct: 2709 IPCEKNDMTFVHC---GNSTIC---IMPRWRCDGDP------DCPDGTDELDCANHTSLS 2756
Query: 1170 CLNGGF-CSYANSNRSLPHC----ICPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMDP 1006
C G F C+ N HC CP G +E C+ C + K P
Sbjct: 2757 CDPGQFRCASGNCIAGSWHCDGEKDCPDG-----SDEINCRTECRHNQ---FACDKTCIP 2808
Query: 1005 ITCSCE-QNAAAHNTDCSPICQKQP-----NWCHNGGRCLDTPGYPGKCKCLP------- 865
+ C+ ++ +D P C +P C + GRC+ K P
Sbjct: 2809 ASWQCDGKSDCEDGSDEGPQCPNRPCRPHLFQCKSSGRCIPQKWVCDGEKDCPSGLGDEG 2868
Query: 864 -RFAGPRCDVPVQCDDYCTNNSKCT--ITNGTHFECDCKPGFKGLRCEQETKCSECSNEA 694
GP+C D CT + +H+ CD G E E C
Sbjct: 2869 SEDEGPQCGGVAHIPDCPPPAHLCTSGLCIDSHYVCDGDEDCPGGDDEYE-GCVPAFQPH 2927
Query: 693 KCIKKPSGTVICQCPQGLGGEYCEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSP 514
C P G+++ QC GL C T + +C +G ++ TS C +
Sbjct: 2928 SC---PGGSLMHQCQDGL----CIFKNQTCDGKPDCGDG---------SDETSSLCAHTR 2971
Query: 513 GFKG---LLCSSNAC---ENFCLHDGNCTLDEYFEPQCECYQAFIGDRCQYRIHQHAV 358
G G C + AC + C +C D E C + I D C++ V
Sbjct: 2972 GCNGTDDFRCKNGACIHADLLCDRRNDCA-DFSDEELCNVNECLIPDICEHECEDKVV 3028
Score = 75.1 bits (183), Expect = 2e-11
Identities = 61/196 (31%), Positives = 86/196 (43%), Gaps = 11/196 (5%)
Frame = -1
Query: 6537 CRPGYFNCGNGLCIPEQKVCNRINDCANFADE-SNCT--CNENEFRC-QSGACIPSKARC 6370
C YF C +G CIP + C+ DC + +DE S C CNE +FRC S CIP+ C
Sbjct: 39 CPASYFTCNDGFCIPMRWKCDSKADCPDMSDEGSECAPKCNEGQFRCGVSRHCIPNNWLC 98
Query: 6369 NHMQDC--NDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDGTNDCYDGSD 6196
+ DC D SDE+ CP + F C+ S CDG DC +D
Sbjct: 99 DGEFDCGKGDISDELNCPNGDTPKCRAFE-----GQCRNGDCLELSRFCDGRWDC--DND 151
Query: 6195 EKDCFVEFDATGGSVSAPRSCDAKTQFA-CLATRTCMPKHWQCDGQPDCADGSDEKNCDA 6019
E C + +A +++ +C Q A C + +P+ D + S+ CD
Sbjct: 152 ELQCDKQ-NAACAALNCSFNCKLTPQGARCYCPKDQVPESSNSTRCVDYDECSEPGTCD- 209
Query: 6018 KKCT----SFEFSCES 5983
+ C S+E SC S
Sbjct: 210 QVCRNTPGSYECSCVS 225
Score = 74.3 bits (181), Expect = 4e-11
Identities = 184/860 (21%), Positives = 289/860 (33%), Gaps = 91/860 (10%)
Frame = -1
Query: 2814 CAQKC---WMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGN----RLHLMSL 2656
C Q C W +A+C C GY N+ L + + F+ + R+ + L
Sbjct: 546 CNQICVPQWTKGFASAKCMCTAGYKL----HNQTTCLLSALDKFLVYSDKHLARISGIPL 601
Query: 2655 ENSQVS----------VLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTV--------GIGN 2530
+ QV V+ PV+N+ L ID +V + Y V G G
Sbjct: 602 DTEQVQQLEQIGEQPDVMVPVYNVSKTL---AIDV--NVRGKAVFYVVADSGASPFGNGE 656
Query: 2529 SRVDIRSKKWSDGLIGSWGEEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVA 2350
IRS+ + + + + +D++++++Y+T + VA
Sbjct: 657 PSCSIRSQSLNGSVSRLLAQGLKRVHAVAFDWINDHLYWTSHKKMQ------------VA 704
Query: 2349 KAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWT---TSAPVPRILSANLDGKPIAQPFKT 2179
++ S + L N+ SL +DP L++W+ + + I S+ +DG
Sbjct: 705 PLRNLS-KVLTFNTDCDAMSLELDPTTGLLYWSQWESQSCEAGIYSSWMDGT-------- 755
Query: 2178 GSQPHKALVERNIFE-----PTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFE 2014
HK L+ + P S+ +D + LYW D+ TIE + DG R + K +
Sbjct: 756 ----HKELLAKGTSSMPMQWPRSLDVDRRTKELYWCDIRLSTIELMRLDGTGREVLFKSD 811
Query: 2013 LGDTPVTMDVLGGYIYLITRQGS-IHRMH------KFTGKTNKYVQKI-REVSPRIQIRV 1858
P ++ G IY + S I R H T + ++Q+ R RI
Sbjct: 812 QFH-PYSIVQNNGLIYWADNKNSTILRFHAHQANLSSTFSSTVHLQRTGRAADLRIFDIA 870
Query: 1857 AHPAKHTVSHITHQKNPCQSDYCPSNTVC-VPD----QDKNGILIPKCLCGPGR------ 1711
+ P T S K P P +C PD IP+ P R
Sbjct: 871 SQPLPQTPSACAQSKCPGMCLNTPKGAICRCPDGFTLNGTGSHCIPQLAPSPIRPNCTSG 930
Query: 1710 FFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCSPQKTCVCPPGFYGRQCEINECSET-- 1537
+ ST++C+ ++ C D ++ P C +N C +T
Sbjct: 931 YMCRSTRQCLDTKDMCDGFEDCEDGIDESSDPKGP--------------CNVNTCDKTHN 976
Query: 1536 -CWNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVC---EGVCGPRGSC--------KT 1393
NG ST + +C Q++C N C E C G C
Sbjct: 977 FVCNGRCYQRSLLCST---IPYCSDGTDQANCHQNTCNSNEFTCHKSGRCIQLTWVNDGV 1033
Query: 1392 VPCPKDEPHCRS-----YSFC---ECDKGWTGPHCRHKADAKVCYGHCFSGGACDGEGPL 1237
V C D+ + S C +C+ G CR AD VC G G D +
Sbjct: 1034 VDCGPDDDSDETSETIFASKCPEFDCNNG----RCRQFAD--VCDGIDNCGNNAD---EM 1084
Query: 1236 NLRCSCGDGLTGNRCQNCVG--------HECLNGGFCSYANSNRSLPHCICPSGFTGDHC 1081
C G R C G H+CL+ + N +S H + G+
Sbjct: 1085 ECEQECEHGEKYCRPIGCYGEMHMCDGIHDCLDFSDEANCNQTKSDNHPVTEWKELGECA 1144
Query: 1080 EEYLCKDACPFGSKCTYDITK---------PMDPITCSCEQNAAAHNTDCSPICQKQPNW 928
+ AC F +C D + D C+ N + + + IC+
Sbjct: 1145 P---LEFACMFPFECIPDFLRCDGISHCFDKTDEFNCT-HINTTRFDMNETVICEHPDRL 1200
Query: 927 CHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSKCTITNGTHFECDCKPGF 748
C G+ +C V D C + C T F C K
Sbjct: 1201 C----------GFSKQC--------------VTVDQLCDGKNDCEDTTDEGFLCADK--- 1233
Query: 747 KGLRCEQETKCSECSNEAKCIKKPSGTVICQCPQGLGGEYCEKITATSCHQLECKNGGYC 568
C++ +CS +C P G IC CP L Y + Q C + C
Sbjct: 1234 ---LCDRGHECSH-----RCHNTPEG-YICSCPDHL---YLQPNGKRCSMQHACDHWDTC 1281
Query: 567 LKPDPSANRTSPTCLCSPGF 508
+ S+ + C C GF
Sbjct: 1282 SQVCESSGK-GYDCRCLDGF 1300
Score = 72.8 bits (177), Expect = 1e-10
Identities = 52/188 (27%), Positives = 75/188 (39%), Gaps = 5/188 (2%)
Frame = -1
Query: 6429 CNENEFRCQSGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQC 6250
C + F C G CIP + +C+ DC D SDE C+ G C + C
Sbjct: 39 CPASYFTCNDGFCIPMRWKCDSKADCPDMSDEGSECAPKCN-------EGQFRCGVSRHC 91
Query: 6249 IHPSWKCDGTNDCYDG--SDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHW 6076
I +W CDG DC G SDE +C G R+ + + + C+
Sbjct: 92 IPNNWLCDGEFDCGKGDISDELNC------PNGDTPKCRAFEGQCR-----NGDCLELSR 140
Query: 6075 QCDGQPDCADGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRD-CPDGEDEHQC-- 5905
CDG+ DC +DE CD + +C + K P +C +D P+ + +C
Sbjct: 141 FCDGRWDC--DNDELQCDKQNAACAALNCSFNCKLTPQGARCYCPKDQVPESSNSTRCVD 198
Query: 5904 ETECDSKG 5881
EC G
Sbjct: 199 YDECSEPG 206
Score = 69.7 bits (169), Expect = 9e-10
Identities = 65/227 (28%), Positives = 84/227 (36%), Gaps = 12/227 (5%)
Frame = -1
Query: 4002 PCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKK 3823
PC A F C C+ CD DC DE +C E QF+CG +
Sbjct: 38 PCPASYFTCN------DGFCIPMRWKCDSKADCPDMSDEGSECAP--KCNEGQFRCGVSR 89
Query: 3822 KCIPLTSVCDKEKDCDDG--SDELNC---EITSCKPDFFACFNGTAISKCIPKEFYCDGE 3658
CIP +CD E DC G SDELNC + C+ C NG C+ +CDG
Sbjct: 90 HCIPNNWLCDGEFDCGKGDISDELNCPNGDTPKCRAFEGQCRNG----DCLELSRFCDGR 145
Query: 3657 DDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQCDGTLDCRDGSDEKGCKKECAIV 3478
DC + + D + F C K P+ +C C K+
Sbjct: 146 WDCDNDELQCDKQNAACAALNCSFNC---KLTPQGARC-------------YCPKDQVPE 189
Query: 3477 CDNS--CVHADD-----LCDGKKKCNDGSDEDEEACVIKQLLEKENR 3358
NS CV D+ CD + C + E +CV K NR
Sbjct: 190 SSNSTRCVDYDECSEPGTCD--QVCRNTPGSYECSCVSGYAKTKGNR 234
Score = 62.0 bits (149), Expect = 2e-07
Identities = 84/379 (22%), Positives = 146/379 (38%), Gaps = 22/379 (5%)
Frame = -1
Query: 2838 AECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMS 2659
AE + G C Q C + C CA GY N+ C P ++ I + ++
Sbjct: 1897 AEWAYRGGCQQLCLATSSIDHVCRCALGYDVEPNNPTGCVPRAEFIFYSIDVLQGVEMID 1956
Query: 2658 LENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDG---- 2491
+ Q P + ++ + Y TL + G++ + S+ DG
Sbjct: 1957 -PSEQFDTPSPAL-VPISRVSSASFIDYLANTDTLYW----GDNELGSISRVKRDGTQRE 2010
Query: 2490 -------LIGSWGEEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTS 2332
L+G +++ G I D++ N+Y++ D + NI D S
Sbjct: 2011 TILEALNLVGY--KQQDWLGGIAIDWVAGNIYWS-----------DTKRNIIEVARLDGS 2057
Query: 2331 TRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALV 2152
R ++V++ +LAVDP++ L+F+ T + R+ LDG +QPF +Q
Sbjct: 2058 HRYVVVSNLEKPTALAVDPLQGLLFYVTQQHIGRV---GLDG---SQPFVLVNQ------ 2105
Query: 2151 ERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGY 1972
R + S+VLD ++YW + + V +DG R + L + PV + +G Y
Sbjct: 2106 TRANWAVGSLVLDIEATKVYWCERYPDALMKVDYDGNLREQLLNESL-NNPVALAKMGDY 2164
Query: 1971 IYLITRQGSIHRMHKFTGKTNKYVQKIREVSP-------RIQIRVAHPA----KHTVSHI 1825
+Y NKY + I V+P ++ ++ A K H+
Sbjct: 2165 LY---------------WAENKYNEGIIRVAPLANLSQSKVVLQTEQDAIRDLKIYSKHL 2209
Query: 1824 THQKNPCQSDYCPSNTVCV 1768
NPC +C+
Sbjct: 2210 QRGSNPCAHSNGACEQLCL 2228
Score = 55.8 bits (133), Expect = 1e-05
Identities = 47/210 (22%), Positives = 73/210 (34%), Gaps = 41/210 (19%)
Frame = -1
Query: 5613 CKPNEWMCDSGQCIDSGRLCDASVDCVDGSDEWVEICSLSEPPRRGCPSGWSCLLTNGTI 5434
C + + C+ G CI CD+ DC D SDE E + C C+ N
Sbjct: 39 CPASYFTCNDGFCIPMRWKCDSKADCPDMSDEGSECAPKCNEGQFRCGVSRHCIPNN--- 95
Query: 5433 GCLQEQQLCDGRRDCMSG------------------IDEQCDNPQGNCSSTRNSCDQTWN 5308
LCDG DC G + QC N G+C CD W+
Sbjct: 96 ------WLCDGEFDCGKGDISDELNCPNGDTPKCRAFEGQCRN--GDCLELSRFCDGRWD 147
Query: 5307 C--------QRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKANCSHFCIDRRDV----- 5167
C +++A + +C L+P + P+++ S C+D +
Sbjct: 148 CDNDELQCDKQNAACAALNCSFNCKLTPQGARCYCPKDQVPESSNSTRCVDYDECSEPGT 207
Query: 5166 ----------GHQCFCAPGYILSENQKDCR 5107
++C C GY ++ + CR
Sbjct: 208 CDQVCRNTPGSYECSCVSGYAKTKGNR-CR 236
Score = 52.4 bits (124), Expect = 1e-04
Identities = 36/95 (37%), Positives = 45/95 (46%), Gaps = 8/95 (8%)
Frame = -1
Query: 5490 PPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSSTRNSCDQTW 5311
P R C SG+ C T CL + +CDG DC GIDE D P+G C+ N+CD+T
Sbjct: 922 PIRPNCTSGYMC---RSTRQCLDTKDMCDGFEDCEDGIDESSD-PKGPCNV--NTCDKTH 975
Query: 5310 N--CQRHAGFES--CS----CDDGYHLSPYDKKTC 5230
N C S CS C DG + + TC
Sbjct: 976 NFVCNGRCYQRSLLCSTIPYCSDGTDQANCHQNTC 1010
Score = 43.9 bits (102), Expect = 0.053
Identities = 116/496 (23%), Positives = 162/496 (32%), Gaps = 75/496 (15%)
Frame = -1
Query: 1806 CQS---DYCPSN--TVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQLREKDQ------ 1660
CQS D PSN T +PD + G C P +F S K C ++
Sbjct: 2656 CQSEDIDMHPSNNNTKEMPDMFRCG----SGECIPRKFLCDSLKDCRDFSDEKMCAPIPC 2711
Query: 1659 EASQCGDYFCYNNAGC-SPQKTCV----CPPGFYGRQCEINECSETCWNGETCAVQEFGS 1495
E + C N+ C P+ C CP G C N S +C G+
Sbjct: 2712 EKNDMTFVHCGNSTICIMPRWRCDGDPDCPDGTDELDCA-NHTSLSCDPGQFRCASGNCI 2770
Query: 1494 TTNVVCH----CPSNYTQSSCATN------VCEGVCGPRGSCKTVPCPKDEPHCRSYSFC 1345
+ C CP + +C T C+ C P C S C
Sbjct: 2771 AGSWHCDGEKDCPDGSDEINCRTECRHNQFACDKTCIPASW-----------QCDGKSDC 2819
Query: 1344 ECDKGWTGPHCRHKADAKVCYGH---CFSGG-------ACDGEGPLNLRCSCGDGLTGNR 1195
E D GP C ++ C H C S G CDGE C GL G+
Sbjct: 2820 E-DGSDEGPQCPNRP----CRPHLFQCKSSGRCIPQKWVCDGEK------DCPSGL-GDE 2867
Query: 1194 CQNCVGHECLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCK--DACPFGSKCTYDIT 1021
G +C GG + P +C SG D Y+C + CP G
Sbjct: 2868 GSEDEGPQC--GGVAHIPDCPP--PAHLCTSGLCID--SHYVCDGDEDCPGGDDEYEGCV 2921
Query: 1020 KPMDPITC-------SCEQNAAAHNT-------DCSPICQKQPNWCHNGGRCLDTPGYPG 883
P +C C+ DC + + C + C T +
Sbjct: 2922 PAFQPHSCPGGSLMHQCQDGLCIFKNQTCDGKPDCGDGSDETSSLCAHTRGCNGTDDF-- 2979
Query: 882 KCK---CLPRFAGPRCDVPVQCDDYCT----NNSKCTITNGTHFECD---------CKPG 751
+CK C+ A CD C D+ N ++C I + EC+ C+PG
Sbjct: 2980 RCKNGACI--HADLLCDRRNDCADFSDEELCNVNECLIPDICEHECEDKVVGYQCHCRPG 3037
Query: 750 FKGLRCEQE--TKCSECSNEAKCIK---KPSGTVICQCPQG--LGGEYCEKITATSCHQL 592
+K L T EC + C + G+ C C +G L + K T+ +L
Sbjct: 3038 YKVLPKSPHLCTDIDECDEQQPCSQTCINTYGSYKCLCAKGYALVDHHTCKATSNVSMEL 3097
Query: 591 ECKNGGYCLKPDPSAN 544
N Y + D + N
Sbjct: 3098 IFSNRYYIRQVDMTGN 3113
>gi|45382557|ref|NP_990573.1| low density lipoprotein-related protein
1; alpha-2-macroglobulin receptor [Gallus gallus]
gi|1708864|sp|P98157|LRP1_CHICK Low-density lipoprotein
receptor-related protein 1 precursor (LRP)
(Alpha-2-macroglobulin receptor) (A2MR)
gi|1079416|pir||A53102 alpha-2-macroglobulin receptor precursor -
chicken
gi|438007|emb|CAA52870.1| alpha-2-macroglobulin receptor [Gallus
gallus]
Length = 4543
Score = 862 bits (2228), Expect = 0.0
Identities = 627/1993 (31%), Positives = 888/1993 (44%), Gaps = 159/1993 (7%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC---TCNENEFRCQS 6400
DE YCS+R C+ G+ +C NG C+ + CN ++DC + +DE C +C EFRC+
Sbjct: 2549 DEKQSYCSSRKCKKGFLHCMNGRCVASRFWCNGVDDCGDNSDEVPCNKTSCAATEFRCRD 2608
Query: 6399 GACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLI--NCATTSQCIHPSWKCD 6226
G+CI + +RCN DC DASDE+ C +CS+ + G+ G C TS C PSW CD
Sbjct: 2609 GSCIGNSSRCNQFIDCEDASDEMNCTATDCSSYFKLGVKGTTFQKCEHTSLCYAPSWVCD 2668
Query: 6225 GTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCAD 6046
G NDC D SDE++C GG C A FAC + R C+P W CD + DC +
Sbjct: 2669 GANDCGDYSDERNC------PGG---RKPKCPA-NYFACPSGR-CIPMTWTCDKEDDCEN 2717
Query: 6045 GSDEKNCDAKK---CTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDE-HQCETECDSKGG 5878
G DE +C ++ C +F C ++ +CI CDG DC DG DE +C S G
Sbjct: 2718 GEDETHCSERQDKFCYPVQFEC-NNHRCISKLWVCDGADDCGDGSDEDSRCRLTTCSTG- 2775
Query: 5877 NATFRCT-NHRCIPMAWRCDGTDDCMDNAKSLGSDE---VDCAAGRTSFHVPSRCADETC 5710
+F+C + C+P W CDG DC D G+DE C T C + C
Sbjct: 2776 --SFQCPGTYVCVPERWLCDGDKDCAD-----GADETLAAGCLYNNTCDEREFMCGNRQC 2828
Query: 5709 VVACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRL-CDASVDCV 5533
+ +CD DC DG DE C P+E+ C +G+C+ + + CD DC
Sbjct: 2829 IP----KHFVCDHDDDCGDGSDESPECEYP-TCGPHEFRCANGRCLSNSQWECDGEFDCH 2883
Query: 5532 DGSDEWVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQ 5353
D SDE + S P + S + C NG C+ E LCD DC G DE
Sbjct: 2884 DHSDEAPKNPRCSSPESKCNDSFFMC--KNGK--CIPEALLCDNNNDCADGSDELNCFIN 2939
Query: 5352 GNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKA-NCSHFCIDR 5176
+ + C Q C+ C C G+ L D KTC+ C CS CI+
Sbjct: 2940 ECLNKKLSGCSQ--ECEDLKIGYKCRCRPGFRLKD-DGKTCIDIDECSTTYPCSQKCINT 2996
Query: 5175 RDVGHQCFCAPGYILS-ENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLTN 4999
++C C GY L +N C+ E ++ + L+ +DG L L N
Sbjct: 2997 LG-SYKCLCIEGYKLKPDNPTSCKAVTDEEPFLIFANRYYLRKLNLDGSNYTLLKQGLNN 3055
Query: 4998 GVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNI 4819
VALD+D + ++YWTDV G+ I M + +V++ DG+AVDW+G N+
Sbjct: 3056 AVALDFDYREQMIYWTDVTTQGSM--IRRMHINGSNVQVLHRTGLSNPDGLAVDWVGGNL 3113
Query: 4818 YYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNM 4639
Y+ D+ D I V + G + R +L + L +PRA+V+D ++WTDWG + IG++ M
Sbjct: 3114 YWCDKGRDTIEVSKLNGAY-RTVLVNSGLREPRALVVDVQNGYLYWTDWGDHSLIGKIGM 3172
Query: 4638 DGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHI 4459
DG+N VI+ D I WPN L +D R+Y+ DA DYI + DGS R VL + HI
Sbjct: 3173 DGTNRSVIV-DTKITWPNGLTLDYINSRIYWADAREDYIEFASLDGSNRHTVLSQDIPHI 3231
Query: 4458 FALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKT 4279
FAL +FEDY+YW+DW +I R HK TG N+ +LI +RPM I HP Q
Sbjct: 3232 FALTLFEDYIYWTDWETKSINRAHKTTGANKTLLI-STLHRPMDIHIYHPYRQP----DV 3286
Query: 4278 ARHPC-SQPARCDNLCIPANTPDLTTSSDNFTCMCAQGF--RSEGRSCVSECKPNDFVCT 4108
HPC + A C NLC L + C C F S+G++CVS C + FVC
Sbjct: 3287 PNHPCKTNNAGCSNLC-------LLSPGGGHKCACPTNFYLGSDGKTCVSNCTASQFVC- 3338
Query: 4107 KTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASK 3928
K KCI WW+ CP F C GQF C +T C +
Sbjct: 3339 KNDKCIPFWWKCDTEDDCGDRSDE----PEDCPEFKCRPGQFQC------STGICTNPAF 3388
Query: 3927 LCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCE 3748
+CDG DC DE A C+ C +QFKC + +CIP C+ + +C DG DE +C
Sbjct: 3389 ICDGDNDCQDNSDE--ANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDEKDCP 3446
Query: 3747 ITSCKPDFFACFNGTAISK-CIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQC-TS 3574
+C P+ F C AI+K CIP+ + CD ++DC +G DEP +C + C ++F+C S
Sbjct: 3447 EVTCAPNQFQC----AITKRCIPRVWVCDRDNDCVDGSDEPANCTQM-TCGVDEFRCKDS 3501
Query: 3573 GKCIPKRRQCDGTLDCRDGSDEKGCKKEC-AIVCD--------NSCVHADDLCDGKKKCN 3421
G+CIP R +CDG DC DGSDE K+EC C+ N CV CD C
Sbjct: 3502 GRCIPARWKCDGEDDCGDGSDEP--KEECDERTCEPYQFRCKNNRCVPGRWQCDYDNDCG 3559
Query: 3420 DGSDEDEEACVIKQLLEKE----NRKC--GGFACDGIVDCEDGSDEKGC---PDLECHLA 3268
D S DEE+C + E E N +C G + CDG DC DGSDEK C + + +
Sbjct: 3560 DNS--DEESCTPRPCSESEFSCANGRCIAGRWKCDGDHDCADGSDEKDCIPRCEFDQYQC 3617
Query: 3267 SNKSLI-----CDGTIDCSSGKDENNCHNNGES---NFFQCSMQTIK--EWQVCDGRWDC 3118
N I CD DC G DE +C + + FQC+ K W+ CDG DC
Sbjct: 3618 KNGHCIPMRWRCDADADCMDGTDEEDCGTGVRTCPLDEFQCNNTLRKPLAWK-CDGEDDC 3676
Query: 3117 ADGLDESPEMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSD----ENPIHCK 2950
D DE+PE C + R C + + CL + CDGI +C D +D E+P
Sbjct: 3677 GDNSDENPEECLKFQCPPNRPFRCKNDRVCLWIGRQ-CDGIDNCGDNTDEKDCESPTAKP 3735
Query: 2949 DMC---KGKYRCTNGRCIDVSARXXXXXXXXXXXXXXXXGAECHHFG------VCAQ--K 2803
C K ++ C N +CI + R E + +C +
Sbjct: 3736 KSCSQDKNEFLCENKKCISANLRCNFFDDCGDGSDEKSCSHEHKSYDCMTNTTMCGDEAQ 3795
Query: 2802 CWMAFNHTARCHCAPGYARTKNDENECEPLSK-----SAEMFITNGNRLHLMS------- 2659
C A + T C C G+ + D+N C+ +++ + N H+ S
Sbjct: 3796 CIQAQSST-YCTCRRGFQKVP-DKNSCQDVNECLRFGTCSQLCNNTKGSHVCSCAKNFMK 3853
Query: 2658 ------LENSQVSVLRPVFNIKM-NLIPGGIDFGYD-VFRTTLMYTVGIGNSRVD----- 2518
E S+ +L + K+ ++ P + Y+ F+ G N R+D
Sbjct: 3854 TDNMCKAEGSEHQILYIADDNKIRSMYPFNPNSAYEPAFQ-------GDENVRIDAMDIY 3906
Query: 2517 IRSKK-----WSDGLIGSWGEEESTAG---------LITYDFMHNNVYFTESSEQNRGVL 2380
++ K W G I S+A I H N+ + RG+
Sbjct: 3907 VKGNKIYWTNWHTGRISYCELPASSAASTASNRNRRQIDGGVTHLNI---SGLKMPRGIA 3963
Query: 2379 FDRQA-NIY----------VAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVP 2233
D A NIY VA+ K + +TLI +++ VDP++ ++W+ P
Sbjct: 3964 VDWVAGNIYWTDSGRDVIEVAQMKGENRKTLISGMIDEPHAIVVDPLRGTMYWSDWGNHP 4023
Query: 2232 RILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVS 2053
+I +A +DG + LV+ NI PT + +D+ NERLYW D I ++
Sbjct: 4024 KIETAAMDG-----------TLRETLVQDNIQWPTGLAVDYHNERLYWADAKLSVIGSIR 4072
Query: 2052 FDGRDRRTVRKFELG-DTPVTMDVLGGYIYLITR-QGSIHRMHKFTGKTNKYVQKIREVS 1879
+G D + G P ++D+ YIY +T I ++HKF K+ ++
Sbjct: 4073 LNGTDPVVAIDNKKGLSHPFSIDIFEDYIYGVTYINNRIFKIHKFGHKS--VTNLTSGLN 4130
Query: 1878 PRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLCGPGRFFEV 1699
+ + H K NPC C + P P C C G+ +
Sbjct: 4131 HATDVVLYHQYKQ-----PEVTNPCDRKKCEWLCLLSPSG-------PVCTCPNGKRLDN 4178
Query: 1698 STKKCMQLREKDQEA----SQCGDYFCYNNAGC----SPQKTCVCPPGFYGRQCEINECS 1543
T C+ + A + D C N C Q C C P + G +C+IN+CS
Sbjct: 4179 GT--CVLIPSPTASAVVPTTDTCDLVCLNGGSCFLNARKQAKCRCQPRYNGERCQINQCS 4236
Query: 1542 ETCWNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHC 1363
+ C NG C G T C CP+ +T S C VC C GSC ++P+C
Sbjct: 4237 DYCQNGGLCTASPSGMPT---CRCPTGFTGSRCDQQVCTNYCHNNGSCTV--NQGNQPNC 4291
Query: 1362 RSYSFCECDKGWTGPHCRHKADAKVCYGHCFSGGAC----DG------------------ 1249
R C + G C+++ C+ +C + G C DG
Sbjct: 4292 R------CPPTFIGDRCQYQQ----CFNYCENNGVCQMSRDGVKQCRCPPQFEGAQCQDN 4341
Query: 1248 ------EGPLNLR-------CSCGDGLTGNRCQNCVGHECLNGGFCSYANSNRSLPHCIC 1108
EG N+ C C DG C C + CLNGG CS ++ + LP C+C
Sbjct: 4342 KCSRCQEGKCNINRQSGDVSCICPDGKIAPSCLTCDSY-CLNGGTCSISDKTQ-LPECLC 4399
Query: 1107 PSGFTGDHCEEYL 1069
P TG CEE++
Sbjct: 4400 PLEVTGMRCEEFI 4412
Score = 374 bits (960), Expect = e-101
Identities = 307/1099 (27%), Positives = 452/1099 (40%), Gaps = 60/1099 (5%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGN-GLCIPEQKVCNRINDCANFADESNC---TCNENEFRC 6406
D+ D C VC P F C N CIP CN ++C + DE +C TC N+F+C
Sbjct: 3398 DNSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDEKDCPEVTCAPNQFQC 3457
Query: 6405 Q-SGACIPSKARCNHMQDCNDASDE-IGCPFRNCSALNEFGMTGLINCATTSQCIHPSWK 6232
+ CIP C+ DC D SDE C C ++EF C + +CI WK
Sbjct: 3458 AITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTC-GVDEF------RCKDSGRCIPARWK 3510
Query: 6231 CDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKT----QFACLATRTCMPKHWQCDG 6064
CDG +DC DGSDE CD +T QF C R C+P WQCD
Sbjct: 3511 CDGEDDCGDGSDE---------------PKEECDERTCEPYQFRCKNNR-CVPGRWQCDY 3554
Query: 6063 QPDCADGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSK 5884
DC D SDE++C + C+ EFSC ++ +CI KCDG DC DG DE C C+
Sbjct: 3555 DNDCGDNSDEESCTPRPCSESEFSC-ANGRCIAGRWKCDGDHDCADGSDEKDCIPRCEFD 3613
Query: 5883 GGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVV 5704
++C N CIPM WRCD DCMD G+DE DC G + + + T
Sbjct: 3614 ----QYQCKNGHCIPMRWRCDADADCMD-----GTDEEDCGTGVRTCPLDEFQCNNT--- 3661
Query: 5703 ACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNE-WMCDSGQ-CIDSGRLCDASVDCVD 5530
+ A CDG DC D DE L QC PN + C + + C+ GR CD +C D
Sbjct: 3662 LRKPLAWKCDGEDDCGDNSDENPEECLKFQCPPNRPFRCKNDRVCLWIGRQCDGIDNCGD 3721
Query: 5529 GSDEWVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQC---DN 5359
+DE + C + C + L C+ C+ DC G DE+ ++
Sbjct: 3722 NTDE--KDCESPTAKPKSCSQDKNEFLCENK-KCISANLRCNFFDDCGDGSDEKSCSHEH 3778
Query: 5358 PQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPK-ANCSHFCI 5182
+C + C C + C+C G+ P DK +C C + CS C
Sbjct: 3779 KSYDCMTNTTMCGDEAQCIQAQSSTYCTCRRGFQKVP-DKNSCQDVNECLRFGTCSQLCN 3837
Query: 5181 DRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLK-LFTIDGHAKATLLSNL 5005
+ + H C CA ++ ++N C+ + + + ++++ ++ + ++
Sbjct: 3838 NTKG-SHVCSCAKNFMKTDNM--CKAEGSEHQILYIADDNKIRSMYPFNPNSAYEPAFQG 3894
Query: 5004 TNGV---ALDYDVKSDLVYWTDVAHDG----------NKAGITSMSNQPNTYRVINSLPT 4864
V A+D VK + +YWT+ H G + A S N+ + L
Sbjct: 3895 DENVRIDAMDIYVKGNKIYWTN-WHTGRISYCELPASSAASTASNRNRRQIDGGVTHLNI 3953
Query: 4863 KGID---GIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQA 4693
G+ GIAVDW+ NIY+TD D I V M+G + L+ G +++P AIV+DPL+
Sbjct: 3954 SGLKMPRGIAVDWVAGNIYWTDSGRDVIEVAQMKGENRKTLISGM-IDEPHAIVVDPLRG 4012
Query: 4692 LVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASC 4513
++W+DWG I MDG+ + ++QD I+WP LAVD +RLY+ DA I S
Sbjct: 4013 TMYWSDWGNHPKIETAAMDGTLRETLVQD-NIQWPTGLAVDYHNERLYWADAKLSVIGSI 4071
Query: 4512 NYDGSKRRMVL--RGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQY 4339
+G+ + + + + H F++ +FEDY+Y + N+ I ++HK G +
Sbjct: 4072 RLNGTDPVVAIDNKKGLSHPFSIDIFEDYIYGVTYINNRIFKIHKF-GHKSVTNLTSGLN 4130
Query: 4338 RPMGFKIVHPSLQSMGSLKTARHPCSQPARCDNLCIPANTPDLTTSSDNFTCMCAQGFRS 4159
+ H Q +PC + +C+ LC+ S C C G R
Sbjct: 4131 HATDVVLYHQYKQ-----PEVTNPCDR-KKCEWLCL--------LSPSGPVCTCPNGKRL 4176
Query: 4158 EGRSCVSECKPN-DFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQ- 3985
+ +CV P V T C C+ G
Sbjct: 4177 DNGTCVLIPSPTASAVVPTTDTC----------------------------DLVCLNGGS 4208
Query: 3984 -FVCGRTAQNATAQCLYASKLCDGVKDCS------GGDDEEPAFCENFECTE--AQFKCG 3832
F+ R Q Y + C + CS G P+ C +C
Sbjct: 4209 CFLNARKQAKCRCQPRYNGERCQ-INQCSDYCQNGGLCTASPSGMPTCRCPTGFTGSRC- 4266
Query: 3831 DKKKCIPLTSVCDKEKDCD-DGSDELNCEITSCKPDFFA-------CFNGTAISKCIPKE 3676
D++ C T+ C C + ++ NC C P F CFN
Sbjct: 4267 DQQVC---TNYCHNNGSCTVNQGNQPNCR---CPPTFIGDRCQYQQCFN----------- 4309
Query: 3675 FYCDGEDDCPEGQDEPDSC-----FGIGECTHEQ-FQCTSGKCIPKRRQCDGTLDCRDGS 3514
YC+ C +D C F +C + +C GKC R+ D + C DG
Sbjct: 4310 -YCENNGVCQMSRDGVKQCRCPPQFEGAQCQDNKCSRCQEGKCNINRQSGDVSCICPDGK 4368
Query: 3513 DEKGCKKECAIVCDNSCVH 3457
C + CD+ C++
Sbjct: 4369 IAPSC-----LTCDSYCLN 4382
Score = 373 bits (958), Expect = e-101
Identities = 470/1860 (25%), Positives = 687/1860 (36%), Gaps = 257/1860 (13%)
Frame = -1
Query: 5199 CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTI----DGH 5032
C C+ R C CA G +LSE+ CR D ++Y R L +I + +
Sbjct: 2162 CQQLCLFRGGGRRTCACAHG-MLSEDGVSCRDYDGY-----LLYSERTILKSIHLSDENN 2215
Query: 5031 AKATL-----LSNLTNGVALDYDVK-----SDLVYWTDVAHDGNKAGITSMSNQPNTYRV 4882
A + ++ N +AL +D + S+ ++++D+ H GN I N T R
Sbjct: 2216 LNAPIKPFEDAEHMKNVIALAFDYRYGTKGSNRIFYSDI-HFGNIQQI----NDDGTGRR 2270
Query: 4881 INSLPTKGIDGIAVDWLGRNIYYTDRNHDAIA---VCDMR-GRFNR---ILLKGTPLNDP 4723
++G+A +Y+T I V R G F R I + G + P
Sbjct: 2271 TIVENVGSVEGLAYHRGWDTLYWTSYTTSTITRHTVDQSRLGAFERETVITMSGD--DHP 2328
Query: 4722 RAIVLDPLQALVFWTDWGAS-AHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYF 4546
RA VLD Q L+FWT+W I R + G+N +I+ D+ IR PN LA+D A+++YF
Sbjct: 2329 RAFVLDECQNLMFWTNWNEQHPSIMRATLSGANVLIII-DQDIRTPNGLAIDHRAEKIYF 2387
Query: 4545 GDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNR 4366
DA D I C YDGS R ++L+ H F LAV+ DY++W+DW ++R +K GT+
Sbjct: 2388 SDATLDKIERCEYDGSHRHVILKSEPVHPFGLAVYGDYIFWTDWVRRAVQRANKYVGTDM 2447
Query: 4365 KVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCS-QPARCDNLCIPANTP--------- 4216
K+L D +PMG V S PC C +LC+ TP
Sbjct: 2448 KLLRVDIPQQPMGIIAVANDTDSC-----ELSPCRVNNGGCQDLCLL--TPKGHVNCSCR 2500
Query: 4215 -------DLTTSSDNFTCMCAQGFRSEGRSCVSECKPNDFVCTKTYKCISSWWRXXXXXX 4057
D T + N TC F C+ + D V K
Sbjct: 2501 GERVLQEDFTCKALNSTCNVHDEFECGNGDCIDFSRTCDGVVHCKDKSDEK--------- 2551
Query: 4056 XXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPA 3877
+ C C G C +C+ + C+GV DC DE P
Sbjct: 2552 -----------QSYCSSRKCKKGFLHC------MNGRCVASRFWCNGVDDCGDNSDEVP- 2593
Query: 3876 FCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCKPDFFACFNGTAI 3697
C C +F+C D CI +S C++ DC+D SDE+NC T C F GT
Sbjct: 2594 -CNKTSCAATEFRCRDGS-CIGNSSRCNQFIDCEDASDEMNCTATDCSSYFKLGVKGTTF 2651
Query: 3696 SKC------IPKEFYCDGEDDCPEGQDEPDSCFGIG-ECTHEQFQCTSGKCIPKRRQCDG 3538
KC + CDG +DC + DE + G +C F C SG+CIP CD
Sbjct: 2652 QKCEHTSLCYAPSWVCDGANDCGDYSDERNCPGGRKPKCPANYFACPSGRCIPMTWTCDK 2711
Query: 3537 TLDCRDGSDEKGCK----KECAIV---CDNS-CVHADDLCDGKKKCNDGSDEDEEACVIK 3382
DC +G DE C K C V C+N C+ +CDG C DGSDED +
Sbjct: 2712 EDDCENGEDETHCSERQDKFCYPVQFECNNHRCISKLWVCDGADDCGDGSDEDSRCRLTT 2771
Query: 3381 QLLEKENRKCGG--------FACDGIVDCEDGSDE---------KGCPDLECHLASN--- 3262
+ +C G + CDG DC DG+DE C + E +
Sbjct: 2772 --CSTGSFQCPGTYVCVPERWLCDGDKDCADGADETLAAGCLYNNTCDEREFMCGNRQCI 2829
Query: 3261 -KSLICDGTIDCSSGKDEN-NC-HNNGESNFFQCS---MQTIKEWQVCDGRWDCADGLDE 3100
K +CD DC G DE+ C + + F+C+ + +W+ CDG +DC D DE
Sbjct: 2830 PKHFVCDHDDDCGDGSDESPECEYPTCGPHEFRCANGRCLSNSQWE-CDGEFDCHDHSDE 2888
Query: 3099 SPE--MCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKGKYR 2926
+P+ C+S +++C + +C+ LCD DC DGSDE + K
Sbjct: 2889 APKNPRCSSPESKCNDSFFMCKNGKCIP-EALLCDNNNDCADGSDELNCFINECLNKKLS 2947
Query: 2925 CTNGRCIDVS----ARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAP 2758
+ C D+ R EC C+QKC + +C C
Sbjct: 2948 GCSQECEDLKIGYKCRCRPGFRLKDDGKTCIDIDECSTTYPCSQKCINTLG-SYKCLCIE 3006
Query: 2757 GYARTKNDENECEPLSKSAEMFITNGNRLHL--MSLENSQVSVLRPVFNIKMNLIPGGID 2584
GY ++ C+ ++ E F+ NR +L ++L+ S ++L+ N + L D
Sbjct: 3007 GYKLKPDNPTSCKAVTDE-EPFLIFANRYYLRKLNLDGSNYTLLKQGLNNAVAL-----D 3060
Query: 2583 FGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGL-----ITYDFMHNNV 2419
F Y R ++Y + IR + GS + GL + D++ N+
Sbjct: 3061 FDY---REQMIYWTDVTTQGSMIRRMH----INGSNVQVLHRTGLSNPDGLAVDWVGGNL 3113
Query: 2418 YFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNS-TGTINSLAVDPIKRLIFWTTSA 2242
Y+ + I V+K + RT++VNS +L VD ++WT
Sbjct: 3114 YWCDKGRDT----------IEVSKLNG-AYRTVLVNSGLREPRALVVDVQNGYLYWTDWG 3162
Query: 2241 PVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIE 2062
I +DG +V+ I P + LD+ N R+YW D + IE
Sbjct: 3163 DHSLIGKIGMDGTN-----------RSVIVDTKITWPNGLTLDYINSRIYWADAREDYIE 3211
Query: 2061 TVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGKTNKYVQKIRE 1885
S DG +R TV ++ + + YIY SI+R HK TG + I
Sbjct: 3212 FASLDGSNRHTVLSQDIPHI-FALTLFEDYIYWTDWETKSINRAHKTTGANKTLL--IST 3268
Query: 1884 VSPRIQIRVAHP-------------------------------------------AKHTV 1834
+ + I + HP K V
Sbjct: 3269 LHRPMDIHIYHPYRQPDVPNHPCKTNNAGCSNLCLLSPGGGHKCACPTNFYLGSDGKTCV 3328
Query: 1833 SHITHQKNPCQSDYC-PSNTVCVPDQDKNGIL-----IPKCLCGPGRFFEVSTKKCMQLR 1672
S+ T + C++D C P C + D P+ C PG+ F+ ST C
Sbjct: 3329 SNCTASQFVCKNDKCIPFWWKCDTEDDCGDRSDEPEDCPEFKCRPGQ-FQCSTGIC---- 3383
Query: 1671 EKDQEASQC-GDYFCYNNAGCSPQKTCVCPPGFYGRQCEINEC---------SETCWNGE 1522
A C GD C +N+ + VC P + + N C + C +GE
Sbjct: 3384 --TNPAFICDGDNDCQDNSDEANCDIHVCLPSQF-KCTNTNRCIPGIFRCNGQDNCGDGE 3440
Query: 1521 --------TCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPH 1366
TCA +F C P + N C +C + C DE
Sbjct: 3441 DEKDCPEVTCAPNQFQCAITKRC-IPRVWVCD--RDNDCVDGSDEPANCTQMTCGVDEFR 3497
Query: 1365 CRSYSFC---------ECDKGWTGPHCRHKADAKVCYGH---CFSGGACDGEGPLNLRCS 1222
C+ C E D G + + D + C + C + G +
Sbjct: 3498 CKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCKNNRCVPGRWQCDYDND 3557
Query: 1221 CGDGLTGNRCQ---------NCVGHECLNGGF-------CSYANSNRS-LPHCICPSGFT 1093
CGD C +C C+ G + C+ + + +P C
Sbjct: 3558 CGDNSDEESCTPRPCSESEFSCANGRCIAGRWKCDGDHDCADGSDEKDCIPRC------- 3610
Query: 1092 GDHCEEYLCKD--ACPFGSKCTYDI----------------TKPMDPITC-SCEQNAAAH 970
++Y CK+ P +C D T P+D C + + A
Sbjct: 3611 --EFDQYQCKNGHCIPMRWRCDADADCMDGTDEEDCGTGVRTCPLDEFQCNNTLRKPLAW 3668
Query: 969 NTDCSPICQKQPNWCHNGGRCLD---TPGYPGKCK----CLPRFAGPRCDVPVQCDD--- 820
D C N N CL P P +CK CL + G +CD C D
Sbjct: 3669 KCDGEDDC--GDNSDENPEECLKFQCPPNRPFRCKNDRVCL--WIGRQCDGIDNCGDNTD 3724
Query: 819 --------------------YCTNNSKCTITN-GTHFECDCKPGFKGLRCEQE------- 724
+ N KC N +F DC G C E
Sbjct: 3725 EKDCESPTAKPKSCSQDKNEFLCENKKCISANLRCNFFDDCGDGSDEKSCSHEHKSYDCM 3784
Query: 723 TKCSECSNEAKCIKKPSGTVICQCPQGLGGEYCEKI-TATSCHQL-ECKNGGYCLKPDPS 550
T + C +EA+CI+ S T C C +G +K+ SC + EC G C
Sbjct: 3785 TNTTMCGDEAQCIQAQSST-YCTCRRGF-----QKVPDKNSCQDVNECLRFGTC---SQL 3835
Query: 549 ANRT--SPTCLCSPGFKGL--LCSSNACENFCLH--DGNCTLDEY-FEPQCECYQAFIGD 391
N T S C C+ F +C + E+ L+ D N Y F P AF GD
Sbjct: 3836 CNNTKGSHVCSCAKNFMKTDNMCKAEGSEHQILYIADDNKIRSMYPFNPNSAYEPAFQGD 3895
Score = 371 bits (952), Expect = e-100
Identities = 263/819 (32%), Positives = 366/819 (44%), Gaps = 36/819 (4%)
Frame = -1
Query: 6579 MFDDEDTKYCSTRVCRPGYFNCGNGLCI--PEQKVCNRINDCANFADESNCT-------- 6430
M+D + + S + CR C + LC+ P + C D AD C
Sbjct: 792 MYDAQQQQVGSNK-CRVNNGGCSS-LCLATPRGRQCACAEDQILGADSVTCEANPSYIPP 849
Query: 6429 --CNENEFRCQSGACIPSKARCNHMQDCNDASDEIG--CPFRNCSALNEFGMTGLINCAT 6262
C EF C++ CI + +C+ DC D SDE C C + C
Sbjct: 850 PQCQPGEFACKNNRCIQERWKCDGDNDCLDNSDEAPELCHQHTCPS-------DRFKCKN 902
Query: 6261 TSQCIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPK 6082
++CI W CDG NDC + DE + S + R+C + QF+C + R C+P
Sbjct: 903 -NRCIPNRWLCDGDNDCGNNEDESN----------STCSARTC-SPNQFSCASGR-CIPI 949
Query: 6081 HWQCDGQPDCADGSDEK-NCDAKKCTSF-EFSCESSKKCIPLEQKCDGRRDCPDGEDEHQ 5908
W CD DC D SDE +C C +F+C + + CI + +CD DC D DE
Sbjct: 950 SWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNGR-CININWRCDNDNDCGDNSDEAG 1008
Query: 5907 CETECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSR 5728
C C S F+C + RCIP+ W CDG +DC D SDE + P
Sbjct: 1009 CSHSCSSN----QFKCNSGRCIPVHWTCDGDNDCGDY-----SDETHANCTNQATRPPGG 1059
Query: 5727 CADETCVVACELTAVL------CDGIQDCSDGFDEKNCASLDRQCKPN-EWMC-DSGQCI 5572
C T C L + CDG DC D DEKNC + C PN ++ C DS +CI
Sbjct: 1060 C--HTDEFQCRLDGLCIPMRWRCDGDTDCMDSSDEKNCEGVTHVCDPNVKFGCKDSARCI 1117
Query: 5571 DSGRLCDASVDCVDGSDEWVEICS--LSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGR 5398
+CD DC D SDE E C + +PP C N T CL ++LCDG
Sbjct: 1118 SKAWVCDGDSDCEDNSDE--ENCESLVCKPPSHTC--------ANNTSICLPPEKLCDGS 1167
Query: 5397 RDCMSGIDEQ--CDNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLR 5224
DC G DE CD CS C G CSC G L D KTC
Sbjct: 1168 DDCGDGSDEGELCDQ----CSLNNGGCSHNCTVAPGEGIV-CSCPLGMELGA-DNKTCQI 1221
Query: 5223 SPSCPK-ANCSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLF 5047
C K CS C ++ +C C G++L + + CR D + I+ H ++
Sbjct: 1222 QSYCAKHLKCSQKC-EQDKYNVKCSCYEGWMLEPDGESCRSLDPFKPFIIFSNRHEIRRI 1280
Query: 5046 TIDGHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLP 4867
+ + L+ L N +ALD+ + +YWTDV D G + ++ V+
Sbjct: 1281 DLHRGDYSVLVPGLRNTIALDFHLNQSSLYWTDVVEDKIYRGKLLENGALTSFEVVIQYG 1340
Query: 4866 TKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALV 4687
+G+AVDW+ NIY+ + N D I V + G LL G + PRAI LDP ++
Sbjct: 1341 LATPEGLAVDWIAGNIYWVESNLDQIEVAKLDGTMRTTLLAG-DIEHPRAIALDPRYGIL 1399
Query: 4686 FWTDWGAS-AHIGRMNMDGSNEQVILQDR-TIRWPNALAVDAPAQRLYFGDAHRDYIASC 4513
FWTDW AS I +M G+ + I ++ + WPN L VD +R+ + DA D I S
Sbjct: 1400 FWTDWDASLPRIEAASMSGAGRRTIHKETGSGGWPNGLTVDYLEKRILWIDARSDAIYSA 1459
Query: 4512 NYDGSKRRMVLRGS--VRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQY 4339
YDG+ VLRG + H FA+ ++ VYW+DW +T+ + +K TG N V +Q
Sbjct: 1460 LYDGTGHIEVLRGHEYLSHPFAVTLYGGEVYWTDWRTNTLAKANKWTGHNVTV-VQRTNT 1518
Query: 4338 RPMGFKIVHPSLQSMGSLKTARHPCSQ---PARCDNLCI 4231
+P ++ HPS Q + A +PC C +LC+
Sbjct: 1519 QPFDLQVYHPSRQPL-----APNPCEANGGKGPCSHLCL 1552
Score = 333 bits (853), Expect = 4e-89
Identities = 313/1240 (25%), Positives = 488/1240 (39%), Gaps = 85/1240 (6%)
Frame = -1
Query: 5259 HLSPYDKKTCLRSPSCPK------ANCSHFCI-DRRDVGHQCFCAPGYILSENQKDCRRN 5101
H+ ++ +RS +C CS C+ C C G+ L + K C++
Sbjct: 465 HIYHQRRQPTVRSHACEPDQFGKPGGCSDICLLGNSHKSRTCRCRSGFSLGSDGKSCKKP 524
Query: 5100 DTIEAEILMVYGHRLK--LFTIDGHAKAT-----LLSNLTNGVALDYDVKSDLVYWTDVA 4942
E E+ +VYG + +D AK + NL N ALD+ ++ +Y+ D
Sbjct: 525 ---EHELFLVYGKGRPGIIRGMDMGAKVPDEHMIPIENLMNPRALDFHAETGFIYFADTT 581
Query: 4941 HDGNKAGITSMSNQPNTYR-VINSLPTKGIDGIAVDWLGRNIYYTD---RNHDAIAVCDM 4774
+ + T R I ++GIAVDW+G N+Y+TD + ++A +
Sbjct: 582 -----SYLIGRQKIDGTERETILKDGIHNVEGIAVDWMGNNLYWTDDGPKKTISVARLEK 636
Query: 4773 RGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDW------GASAHIGRMNMDGSNEQVIL 4612
+ + L++G + PRAIV+DPL ++WTDW I R MDGSN V +
Sbjct: 637 AAQTRKTLIEGK-MTHPRAIVVDPLNGWMYWTDWEEDPKDSKRGKIERAWMDGSNRNVFI 695
Query: 4611 QDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRG-SVRHIFALAVFED 4435
+T+ WPN L++D PA+ LY+ DA D I +G++R++V G + H F L +
Sbjct: 696 TSKTVLWPNGLSLDIPAKILYWVDAFYDRIEMVYLNGTERKIVYEGPELNHAFGLCHYSS 755
Query: 4434 YVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKI--VHPSLQSMGSLKTARHPCS 4261
+++W+++ + +I R+ + + K + + RP F+I Q +GS K
Sbjct: 756 FLFWTEYRSGSIYRLDQ----SSKAVSLLRNERPPIFEIRMYDAQQQQVGSNKCR----V 807
Query: 4260 QPARCDNLCIP-------ANTPDLTTSSDNFTCMCAQGFRSEGRSCVSECKPNDFVCTKT 4102
C +LC+ A D +D+ TC + +C+P +F C K
Sbjct: 808 NNGGCSSLCLATPRGRQCACAEDQILGADSVTCEANPSYIPP-----PQCQPGEFAC-KN 861
Query: 4101 YKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLC 3922
+CI W+ C
Sbjct: 862 NRCIQERWK--------------------------------------------------C 871
Query: 3921 DGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELN--CE 3748
DG DC DE P C C +FKC +CIP +CD + DC + DE N C
Sbjct: 872 DGDNDCLDNSDEAPELCHQHTCPSDRFKC-KNNRCIPNRWLCDGDNDCGNNEDESNSTCS 930
Query: 3747 ITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGK 3568
+C P+ F+C +G +CIP + CD +DDC + DE SC QF C +G+
Sbjct: 931 ARTCSPNQFSCASG----RCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNGR 986
Query: 3567 CIPKRRQCDGTLDCRDGSDEKGCKKECA---IVCDNS-CVHADDLCDGKKKCNDGSDEDE 3400
CI +CD DC D SDE GC C+ C++ C+ CDG C D SDE
Sbjct: 987 CININWRCDNDNDCGDNSDEAGCSHSCSSNQFKCNSGRCIPVHWTCDGDNDCGDYSDETH 1046
Query: 3399 EACVIKQLLEKENRKCGG------------------FACDGIVDCEDGSDEKGCPDL--- 3283
C + R GG + CDG DC D SDEK C +
Sbjct: 1047 ANCT-----NQATRPPGGCHTDEFQCRLDGLCIPMRWRCDGDTDCMDSSDEKNCEGVTHV 1101
Query: 3282 ----------ECHLASNKSLICDGTIDCSSGKDENNCHN-NGESNFFQCSMQT---IKEW 3145
+ +K+ +CDG DC DE NC + + C+ T +
Sbjct: 1102 CDPNVKFGCKDSARCISKAWVCDGDSDCEDNSDEENCESLVCKPPSHTCANNTSICLPPE 1161
Query: 3144 QVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDEN 2965
++CDG DC DG DE E+C G C +C G+D
Sbjct: 1162 KLCDGSDDCGDGSDEG-ELCDQCS---LNNGGCSHNCTVAPGEGIVCSCPLGMELGADNK 1217
Query: 2964 PIHCKDMCKGKYRCTNGRCIDVSARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFN 2785
+ C + C+QKC
Sbjct: 1218 TCQIQSYCAKHLK-------------------------------------CSQKCEQD-K 1239
Query: 2784 HTARCHCAPGYARTKNDENECEPLSKSAEMFI-TNGNRLHLMSLENSQVSVLRPVFNIKM 2608
+ +C C G+ + D C L I +N + + + L SVL P
Sbjct: 1240 YNVKCSCYEGW-MLEPDGESCRSLDPFKPFIIFSNRHEIRRIDLHRGDYSVLVPGLR--- 1295
Query: 2607 NLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGLIT----- 2443
N I +DF + +Y + ++ R K +G + S+ E GL T
Sbjct: 1296 NTI--ALDFH---LNQSSLYWTDVVEDKI-YRGKLLENGALTSF-EVVIQYGLATPEGLA 1348
Query: 2442 YDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRL 2263
D++ N+Y+ ES+ I VAK T TL+ ++A+DP +
Sbjct: 1349 VDWIAGNIYWVESNLD----------QIEVAKLDGTMRTTLLAGDIEHPRAIALDPRYGI 1398
Query: 2262 IFWTT-SAPVPRILSANLDGKPIAQPFK-TGSQPHKALVERNIFEPTSMVLDFSNERLYW 2089
+FWT A +PRI +A++ G K TGS P + +D+ +R+ W
Sbjct: 1399 LFWTDWDASLPRIEAASMSGAGRRTIHKETGSGGW----------PNGLTVDYLEKRILW 1448
Query: 2088 IDVLKRTIETVSFDGRDR-RTVRKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGK 1915
ID I + +DG +R E P + + GG +Y R ++ + +K+TG
Sbjct: 1449 IDARSDAIYSALYDGTGHIEVLRGHEYLSHPFAVTLYGGEVYWTDWRTNTLAKANKWTGH 1508
Query: 1914 TNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSD 1795
VQ R + ++V HP++ ++ NPC+++
Sbjct: 1509 NVTVVQ--RTNTQPFDLQVYHPSRQPLA-----PNPCEAN 1541
Score = 197 bits (500), Expect = 4e-48
Identities = 146/525 (27%), Positives = 239/525 (44%), Gaps = 33/525 (6%)
Frame = -1
Query: 5619 RQCKPNEWMC-DSGQCIDSGRLCDASVDCVDGSDEWVEICSLSEPPRRGC-PSGWSCLLT 5446
+ C P ++ C D CI G CD DC DGSDE +IC S+ R C P+ +CL
Sbjct: 27 KTCSPKQFACKDQITCISKGWRCDGEKDCPDGSDESPDICPQSKVSR--CQPNEHNCL-- 82
Query: 5445 NGTIGCLQEQQLCDGRRDCMSGIDE--QCDNPQGNCSSTRNSCDQTWNCQRHA----GFE 5284
GT C+ +LC+G DC G DE C NC++ CQ H
Sbjct: 83 -GTELCIHMSKLCNGLHDCFDGSDEGPHCREQLANCTAL--------GCQHHCVPTLSGP 133
Query: 5283 SCSCDDGYHLSPYDKKTCLRSPSCPK-ANCSHFCIDRRDVGHQCFCAPGYILSENQKDCR 5107
+C C++ + L+ D+++C C CS C + + C C GY+L + + C+
Sbjct: 134 ACYCNNSFQLAE-DRRSCKDFDECTVYGTCSQTCTNTEG-SYTCSCVEGYLLQPDNRSCK 191
Query: 5106 -RNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLT-----NGVALDYDVKSDLVYWTDV 4945
+N+ ++ +++ + + + + N+T A+D++ D V W V
Sbjct: 192 AKNEPVDRPPVLLIANSQNILAT--YLSGAPVPNITPTSAKQTTAMDFNYIEDTVCWVHV 249
Query: 4944 AHDGNKAGITSMSNQPNTY-----RVIN-SLPTKGIDGIAVDWLGRNIYYTDRNHDAIAV 4783
++ I + PN R IN SL ++ +A+DWL N Y+ D D I V
Sbjct: 250 GDSASQT-ILKCAKIPNLKGFVEERSINISLSLHQVEQMAIDWLTGNFYFVDDIDDRIFV 308
Query: 4782 CDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDR 4603
C+ G + L L +P+ I LDP VF+TD+G + R +MDG N + L D
Sbjct: 309 CNKNG-LTCVTLLDLELYNPKGIALDPAMGKVFFTDYGQIPKVERCDMDGQN-RTKLVDS 366
Query: 4602 TIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRG-SVRHIFALAVFEDYVY 4426
I +P+ + +D ++ +Y+ DA+ DYI +Y+G R +++G + H++ L VFE+Y+Y
Sbjct: 367 KIVFPHGITLDLVSRLVYWADAYLDYIEVVDYEGKNRHTIIQGILIEHLYGLTVFENYLY 426
Query: 4425 WSDWHNHTIERVHKITGTNR----KVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPC-- 4264
++ N ++ + NR + + + + I H Q H C
Sbjct: 427 ATNSDNANAQQKTSVIRVNRFNSTEYQVVTRVDKGGALHIYHQRRQP----TVRSHACEP 482
Query: 4263 ---SQPARCDNLCIPANTPDLTTSSDNFTCMCAQGFR--SEGRSC 4144
+P C ++C+ N S + TC C GF S+G+SC
Sbjct: 483 DQFGKPGGCSDICLLGN------SHKSRTCRCRSGFSLGSDGKSC 521
Score = 160 bits (405), Expect = 4e-37
Identities = 110/369 (29%), Positives = 175/369 (46%), Gaps = 11/369 (2%)
Frame = -1
Query: 5217 SCPKANCSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTID 5038
S +CS C+ + C C GY L Q+ C + + + +L ++ +D
Sbjct: 1847 SVNNGDCSQLCLPTSETSRSCMCTAGYSLKSGQQSC---EGVGSFLLYSVHEGIRGIPLD 1903
Query: 5037 GHAKATLL---SNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLP 4867
+ K+ L S + V +D+ ++D +YW D+ G++++S +
Sbjct: 1904 PNDKSDALVPVSGTSLAVGIDFHAENDTIYWVDM-------GLSTISRAKRDQTWREDVV 1956
Query: 4866 TKGI---DGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQ 4696
T GI +GIAVDW+ NIY+TD+ D I V + G F +++ L+ PRAI + P +
Sbjct: 1957 TNGIGRVEGIAVDWIAGNIYWTDQGFDVIEVARLNGSFRYVVI-SQGLDKPRAITVHPEK 2015
Query: 4695 ALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIAS 4516
+FWT+WG I R +DG+ E+++L + +I WPN ++VD +LY+ DA D I
Sbjct: 2016 GYLFWTEWGQYPRIERSRLDGT-ERMVLVNVSISWPNGISVDYEDGKLYWCDARTDKIER 2074
Query: 4515 CNYD-GSKRRMVLRGSVRHIFALAVFEDYVYWSD--WHNHTIERVHKITGTNRKVLIQDK 4345
+ + G R +VL +F+++VFEDY+YWSD N +I+R K T L
Sbjct: 2075 IDLETGENREVVLSSDNMDMFSVSVFEDYIYWSDRTHANGSIKRGSKDNATESVSLRTGI 2134
Query: 4344 QYRPMGFKIVHPSLQSMGSLKTARHPCSQ-PARCDNLCIPANTPDLTTSSDNFTCMCAQG 4168
+ K+ + + Q + C+Q C LC L TC CA G
Sbjct: 2135 GVQLKDIKVFNRARQK------GTNVCAQNNGGCQQLC-------LFRGGGRRTCACAHG 2181
Query: 4167 FRSE-GRSC 4144
SE G SC
Sbjct: 2182 MLSEDGVSC 2190
Score = 129 bits (325), Expect = 7e-28
Identities = 98/368 (26%), Positives = 168/368 (45%), Gaps = 13/368 (3%)
Frame = -1
Query: 5208 KANCSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTID--- 5038
K CSH C+ + C C L ++ C E + ++Y ++++ +D
Sbjct: 1544 KGPCSHLCLINYNRTLSCACPHLMKLDKDNTTC-----YEFKKFLLYARQMEIRGVDIDN 1598
Query: 5037 ---GHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLP 4867
+ + + ++ N +DYD +YW+DV K + + + S
Sbjct: 1599 PYYNYIISFTVPDIDNVTVVDYDAVEQRIYWSDVRTQTIKRAFINGTG----VETVVSAD 1654
Query: 4866 TKGIDGIAVDWLGRNIYYT--DRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQA 4693
G++VDW+ RN+++T D N I V + G F +++G L+ P +V+ PL
Sbjct: 1655 LPNAHGLSVDWVSRNLFWTSYDTNKKQINVARLDGSFKNAVIQG--LDKPHCLVVHPLHG 1712
Query: 4692 LVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASC 4513
++WTD +I NMDGSN ++ ++ R P LA+D P +LY+ + I C
Sbjct: 1713 KLYWTD---GDNISVANMDGSNRTLLFTNQ--RGPVGLAIDYPESKLYWISSGNGTINRC 1767
Query: 4512 NYDGSKRRMV--LRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQY 4339
N DGS ++ ++ + ALA+ D ++W+D + + +K GT VL ++
Sbjct: 1768 NLDGSDLEVIVAVKSQLSKATALAIMGDKLWWADQASERMGTCNKKDGTEVTVL-RNSTT 1826
Query: 4338 RPMGFKIVHPSLQSMGSLKTARHPCS-QPARCDNLCIPANTPDLTTSSDNFTCMCAQGF- 4165
M K+ S+Q GS +PCS C LC+P TS + +CMC G+
Sbjct: 1827 LVMLMKVYDESIQQAGS-----NPCSVNNGDCSQLCLP-------TSETSRSCMCTAGYS 1874
Query: 4164 -RSEGRSC 4144
+S +SC
Sbjct: 1875 LKSGQQSC 1882
Score = 117 bits (294), Expect = 3e-24
Identities = 89/342 (26%), Positives = 127/342 (37%), Gaps = 3/342 (0%)
Frame = -1
Query: 1170 CLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCSC 991
CLNGG C + N+ R C C + G+ C+ C D
Sbjct: 4203 CLNGGSC-FLNA-RKQAKCRCQPRYNGERCQINQCSD----------------------- 4237
Query: 990 EQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYCT 811
+C NGG C +P C+C F G RCD V C +YC
Sbjct: 4238 --------------------YCQNGGLCTASPSGMPTCRCPTGFTGSRCDQQV-CTNYCH 4276
Query: 810 NNSKCTITNGTHFECDCKPGFKGLRCEQETKCSECSNEAKCIKKPSGTVICQCPQGLGGE 631
NN CT+ G C C P F G RC+ + + C N C G C+CP G
Sbjct: 4277 NNGSCTVNQGNQPNCRCPPTFIGDRCQYQQCFNYCENNGVCQMSRDGVKQCRCPPQFEGA 4336
Query: 630 YCEKITATSCHQLECKNGGYCLKPDPSANRTS--PTCLCSPGFKGLLCSSNACENFCLHD 457
C+ + C + +C + NR S +C+C G C + C+++CL+
Sbjct: 4337 QCQDNKCSRCQEGKC-----------NINRQSGDVSCICPDGKIAPSCLT--CDSYCLNG 4383
Query: 456 GNCTLDEYFE-PQCECYQAFIGDRCQYRIHQHAVIFSDDDSGWIKSFXXXXXXXXXXXXX 280
G C++ + + P+C C G RC+ I + SG S
Sbjct: 4384 GTCSISDKTQLPECLCPLEVTGMRCE------EFIVGEQQSGRTASI-VIPILLLLLLLA 4436
Query: 279 XXIFANRSNRFAVFRQFRHNPLQNQGAPVDQFSNPAYLIDEG 154
FA R + F+H + N GA + NP Y + EG
Sbjct: 4437 VVAFAWYKWRIKGAKGFQHQRMTN-GAMNVEIGNPTYKMYEG 4477
Score = 114 bits (285), Expect = 3e-23
Identities = 122/500 (24%), Positives = 191/500 (37%), Gaps = 22/500 (4%)
Frame = -1
Query: 3153 KEWQVCDGRWDCADGLDESPEMC-ASRKARCFRIGY-CDDKKQCLDVSTALCDGIRDCFD 2980
K W+ CDG DC DG DESP++C S+ +RC + C + C+ +S LC+G+ DCFD
Sbjct: 45 KGWR-CDGEKDCPDGSDESPDICPQSKVSRCQPNEHNCLGTELCIHMS-KLCNGLHDCFD 102
Query: 2979 GSDENPIHCKDMCKGKYRCT----NGRCIDV----SARXXXXXXXXXXXXXXXXGAECHH 2824
GSDE P HC++ CT C+ + EC
Sbjct: 103 GSDEGP-HCREQLA---NCTALGCQHHCVPTLSGPACYCNNSFQLAEDRRSCKDFDECTV 158
Query: 2823 FGVCAQKCWMAFNHTARCHCAPGYARTKNDENEC----EPLSKSAEMFITNGNRLHLMSL 2656
+G C+Q C + C C GY + D C EP+ + + I N + L
Sbjct: 159 YGTCSQTCTNT-EGSYTCSCVEGYL-LQPDNRSCKAKNEPVDRPPVLLIANSQNILATYL 216
Query: 2655 ENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSW 2476
+ V + P + +DF Y + T VG S+ ++ K L G
Sbjct: 217 SGAPVPNITPTSAKQTT----AMDFNY-IEDTVCWVHVGDSASQTILKCAK-IPNLKGFV 270
Query: 2475 GEEESTAGL-------ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLI 2317
E L + D++ N YF + D I+V + TL+
Sbjct: 271 EERSINISLSLHQVEQMAIDWLTGNFYFVD----------DIDDRIFVCNKNGLTCVTLL 320
Query: 2316 VNSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIF 2137
+A+DP +F+T +P++ ++DG Q LV+ I
Sbjct: 321 DLELYNPKGIALDPAMGKVFFTDYGQIPKVERCDMDG-----------QNRTKLVDSKIV 369
Query: 2136 EPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT 1957
P + LD + +YW D IE V ++G++R T+ + L + + V Y+Y
Sbjct: 370 FPHGITLDLVSRLVYWADAYLDYIEVVDYEGKNRHTIIQGILIEHLYGLTVFENYLYATN 429
Query: 1956 RQGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNT 1777
+ + + N++ +V R+ K HI HQ+ +
Sbjct: 430 SDNANAQQKTSVIRVNRFNSTEYQVVTRVD-------KGGALHIYHQRR----QPTVRSH 478
Query: 1776 VCVPDQ-DKNGILIPKCLCG 1720
C PDQ K G CL G
Sbjct: 479 ACEPDQFGKPGGCSDICLLG 498
Score = 92.8 bits (229), Expect = 1e-16
Identities = 201/893 (22%), Positives = 309/893 (34%), Gaps = 103/893 (11%)
Frame = -1
Query: 2820 GVCAQKCWMAFNHTAR-CHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQ 2644
G C+ C + +H +R C C G++ +D C+ + G + ++
Sbjct: 489 GGCSDICLLGNSHKSRTCRCRSGFS-LGSDGKSCKKPEHELFLVYGKGRPGIIRGMDMGA 547
Query: 2643 VSVLRPVFNIKMNLIPGGIDF----GYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSW 2476
+ I+ + P +DF G+ F T Y +G R DG+
Sbjct: 548 KVPDEHMIPIENLMNPRALDFHAETGFIYFADTTSYLIGRQKIDGTERETILKDGIHNVE 607
Query: 2475 GEEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTST--RTLIVNSTG 2302
G I D+M NN+Y+T+ + I VA+ + + +TLI
Sbjct: 608 G--------IAVDWMGNNLYWTDDGPKK---------TISVARLEKAAQTRKTLIEGKMT 650
Query: 2301 TINSLAVDPIKRLIFWTTSAPVPRILSANLDGK--PIAQPFKTGSQPHKALVERNIFEPT 2128
++ VDP+ ++WT P+ D K I + + GS + + + + P
Sbjct: 651 HPRAIVVDPLNGWMYWTDWEEDPK------DSKRGKIERAWMDGSNRNVFITSKTVLWPN 704
Query: 2127 SMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKF-ELGDTPVTMDVLGGYIYLITRQ 1951
+ LD + LYW+D IE V +G +R+ V + EL + R
Sbjct: 705 GLSLDIPAKILYWVDAFYDRIEMVYLNGTERKIVYEGPELNHAFGLCHYSSFLFWTEYRS 764
Query: 1950 GSIHRMHKFTGKTNKYVQKIREVSPRI-QIRVAHPAKHTV-SHITHQKNPCQSDYCPSNT 1777
GSI+R+ + ++K V +R P I +IR+ + V S+ N S C +
Sbjct: 765 GSIYRLDQ----SSKAVSLLRNERPPIFEIRMYDAQQQQVGSNKCRVNNGGCSSLCLATP 820
Query: 1776 -----VCVPDQ---------DKNGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCGD 1639
C DQ + N IP C PG F +C+Q R K GD
Sbjct: 821 RGRQCACAEDQILGADSVTCEANPSYIPPPQCQPGEF-ACKNNRCIQERWKCD-----GD 874
Query: 1638 YFCYNNAGCSPQKTC---VCPPGFYGRQCEINECSETCW---NGETCAVQEFGSTTNVVC 1477
C +N+ +P+ C CP + +C+ N C W C E S +
Sbjct: 875 NDCLDNSDEAPE-LCHQHTCPSDRF--KCKNNRCIPNRWLCDGDNDCGNNEDESNSTCSA 931
Query: 1476 H-CPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHKA 1300
C N Q SCA+ C + + C D+ +C R
Sbjct: 932 RTCSPN--QFSCASGRCIPI--------SWTCDLDD---------DCGD-------RSDE 965
Query: 1299 DAKVCYGHCF-------SGGACDGEGPLNLRCS----CGDGLTGNRCQNCVGHECLNGGF 1153
A Y CF + G C +N RC CGD C H C + F
Sbjct: 966 SASCAYPTCFPLTQFTCNNGRCIN---INWRCDNDNDCGDNSDEAGCS----HSCSSNQF 1018
Query: 1152 CSYANSNRSLP-HCICPS-GFTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCSCEQNA 979
NS R +P H C GD+ +E + CT T+P P C ++
Sbjct: 1019 --KCNSGRCIPVHWTCDGDNDCGDYSDET--------HANCTNQATRP--PGGCHTDEFQ 1066
Query: 978 AAHNTDCSPICQKQPNW-CHNGGRCLDTPGYPGKCKCLPRFAGPR----CDVPVQCDD-- 820
+ C P+ W C C+D+ C+ + P C +C
Sbjct: 1067 CRLDGLCIPM-----RWRCDGDTDCMDSSDEKN-CEGVTHVCDPNVKFGCKDSARCISKA 1120
Query: 819 -YCTNNSKCTITNGTHFECD---CKPGFKGLR------------CEQETKCSECSNEAK- 691
C +S C N C+ CKP C+ C + S+E +
Sbjct: 1121 WVCDGDSDCE-DNSDEENCESLVCKPPSHTCANNTSICLPPEKLCDGSDDCGDGSDEGEL 1179
Query: 690 --------------CIKKPSGTVICQCPQG--LGGE--------YCEKITATS--CHQ-- 595
C P ++C CP G LG + YC K S C Q
Sbjct: 1180 CDQCSLNNGGCSHNCTVAPGEGIVCSCPLGMELGADNKTCQIQSYCAKHLKCSQKCEQDK 1239
Query: 594 --LECK-NGGYCLKPDPSANRTSPTCLCSPGFKGLLCSSNACE--NFCLHDGN 451
++C G+ L+PD +C FK + SN E LH G+
Sbjct: 1240 YNVKCSCYEGWMLEPD------GESCRSLDPFKPFIIFSNRHEIRRIDLHRGD 1286
Score = 84.3 bits (207), Expect = 4e-14
Identities = 57/173 (32%), Positives = 73/173 (41%), Gaps = 4/173 (2%)
Frame = -1
Query: 882 KCK--CLPRFAGPRCDVPVQCDDYCTNNSKCTITNGTHFECDCKPGFKGLRCEQETKCSE 709
KC+ CL +GP C P N K + NGT C P T +
Sbjct: 4154 KCEWLCLLSPSGPVCTCP---------NGK-RLDNGT---CVLIPSPTASAVVPTTDTCD 4200
Query: 708 --CSNEAKCIKKPSGTVICQCPQGLGGEYCEKITATSCHQLECKNGGYCLKPDPSANRTS 535
C N C C+C GE C+ C C+NGG C PS
Sbjct: 4201 LVCLNGGSCFLNARKQAKCRCQPRYNGERCQ---INQCSDY-CQNGGLCTA-SPSG---M 4252
Query: 534 PTCLCSPGFKGLLCSSNACENFCLHDGNCTLDEYFEPQCECYQAFIGDRCQYR 376
PTC C GF G C C N+C ++G+CT+++ +P C C FIGDRCQY+
Sbjct: 4253 PTCRCPTGFTGSRCDQQVCTNYCHNNGSCTVNQGNQPNCRCPPTFIGDRCQYQ 4305
Score = 83.2 bits (204), Expect = 8e-14
Identities = 57/187 (30%), Positives = 81/187 (42%), Gaps = 12/187 (6%)
Frame = -1
Query: 6156 SVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADGSDEK-----NCDAKKCTSFEFS 5992
++ AP++C K QFAC TC+ K W+CDG+ DC DGSDE +C E +
Sbjct: 22 ALEAPKTCSPK-QFACKDQITCISKGWRCDGEKDCPDGSDESPDICPQSKVSRCQPNEHN 80
Query: 5991 CESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNATFRCTNHRCIPMAWRCDGTD 5812
C ++ CI + + C+G DC DG DE C + N T H C+P G
Sbjct: 81 CLGTELCIHMSKLCNGLHDCFDGSDE---GPHCREQLANCTALGCQHHCVP---TLSGPA 134
Query: 5811 DCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVV-ACELTAVLCDGIQDCS--DGF-- 5647
+N+ L D C + DE V C T +G CS +G+
Sbjct: 135 CYCNNSFQLAEDRRSC-----------KDFDECTVYGTCSQTCTNTEGSYTCSCVEGYLL 183
Query: 5646 --DEKNC 5632
D ++C
Sbjct: 184 QPDNRSC 190
Score = 75.9 bits (185), Expect = 1e-11
Identities = 68/286 (23%), Positives = 103/286 (35%), Gaps = 12/286 (4%)
Frame = -1
Query: 6051 ADGSDEKNCDAKKCTSFEFSCESSKKCIP---LEQKCDGRRDCPDGEDEHQCETECDSKG 5881
A +D +C+ C C+ P + C G R +++ C+ +
Sbjct: 2463 AVANDTDSCELSPCRVNNGGCQDLCLLTPKGHVNCSCRGERVL---QEDFTCKALNSTCN 2519
Query: 5880 GNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVA 5701
+ F C N CI + CDG C D + ++ + R C + CV
Sbjct: 2520 VHDEFECGNGDCIDFSRTCDGVVHCKDKS----DEKQSYCSSRKCKKGFLHCMNGRCVA- 2574
Query: 5700 CELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASVDCVDGSD 5521
+ C+G+ DC D DE C C E+ C G CI + C+ +DC D SD
Sbjct: 2575 ---SRFWCNGVDDCGDNSDEVPCNK--TSCAATEFRCRDGSCIGNSSRCNQFIDCEDASD 2629
Query: 5520 EWVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQG--- 5350
E + + G + T C +CDG DC DE+ + P G
Sbjct: 2630 EMNCTATDCSSYFKLGVKGTTFQKCEHTSLCYAPSWVCDGANDCGDYSDER-NCPGGRKP 2688
Query: 5349 NCSSTRNSC------DQTWNCQRHAGFESCSCDDGYHLSPYDKKTC 5230
C + +C TW C + E + +D H S K C
Sbjct: 2689 KCPANYFACPSGRCIPMTWTCDKEDDCE--NGEDETHCSERQDKFC 2732
Score = 70.9 bits (172), Expect = 4e-10
Identities = 154/713 (21%), Positives = 231/713 (31%), Gaps = 67/713 (9%)
Frame = -1
Query: 2349 KAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQ 2170
K T T++ + + +AVD + ++WT P I A L+ +Q
Sbjct: 589 KIDGTERETILKDGIHNVEGIAVDWMGNNLYWTDDGPKKTISVARLE---------KAAQ 639
Query: 2169 PHKALVERNIFEPTSMVLDFSNERLYWID-------VLKRTIETVSFDGRDRRT--VRKF 2017
K L+E + P ++V+D N +YW D + IE DG +R K
Sbjct: 640 TRKTLIEGKMTHPRAIVVDPLNGWMYWTDWEEDPKDSKRGKIERAWMDGSNRNVFITSKT 699
Query: 2016 ELGDTPVTMDVLGGYIYLITRQGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHT 1837
L +++D+ +Y + M G K V + E++ H
Sbjct: 700 VLWPNGLSLDIPAKILYWVDAFYDRIEMVYLNGTERKIVYEGPELN------------HA 747
Query: 1836 VSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQLREKDQE 1657
+ ++Y S ++ DQ + + + P ++R D +
Sbjct: 748 FGLCHYSSFLFWTEY-RSGSIYRLDQSSKAVSLLRNERPP----------IFEIRMYDAQ 796
Query: 1656 ASQCGDYFC-YNNAGCSPQKTCVCPPGFYGRQCEINECSETCWNGETCAVQEFGSTTNVV 1480
Q G C NN GCS C+ P GRQC CA + +V
Sbjct: 797 QQQVGSNKCRVNNGGCS--SLCLATPR--GRQC-------------ACAEDQILGADSVT 839
Query: 1479 CHCPSNYTQSSCATNVCEGVCGP-RGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHK 1303
C +Y + C P +CK C ++ C + C D P H+
Sbjct: 840 CEANPSY--------IPPPQCQPGEFACKNNRCIQERWKCDGDNDC-LDNSDEAPELCHQ 890
Query: 1302 ADAKVCYGHCFSGGACDGEGPLNLRCSC-GDGLTGNRCQNCVGHECLNGGFCSYANSNRS 1126
C F C + R C GD GN + + CS + +
Sbjct: 891 ---HTCPSDRFK---CKNNRCIPNRWLCDGDNDCGNNEDE--SNSTCSARTCSPNQFSCA 942
Query: 1125 LPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCS----------CEQ-NA 979
CI P +T D ++ C D + C Y P+ TC+ C+ N
Sbjct: 943 SGRCI-PISWTCDLDDD--CGDRSDESASCAYPTCFPLTQFTCNNGRCININWRCDNDND 999
Query: 978 AAHNTD---CSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDY--- 817
N+D CS C C N GRC+ CD C DY
Sbjct: 1000 CGDNSDEAGCSHSCSSNQFKC-NSGRCIPVHW--------------TCDGDNDCGDYSDE 1044
Query: 816 ----CTNNSKCTITNGTH---FECD----CKPGFKGLRCEQETKCSE------------- 709
CTN + G H F+C C P RC+ +T C +
Sbjct: 1045 THANCTNQATRP-PGGCHTDEFQCRLDGLCIP--MRWRCDGDTDCMDSSDEKNCEGVTHV 1101
Query: 708 --------CSNEAKCIKKPSGTVIC----QCPQGLGGEYCEKITATSCHQLECKNGGYCL 565
C + A+CI K +C C E CE + N CL
Sbjct: 1102 CDPNVKFGCKDSARCISK---AWVCDGDSDCEDNSDEENCESLVCKPPSHTCANNTSICL 1158
Query: 564 KPDPSANRTSPTCLCSPGF-KGLLCSSNACEN-FCLHDGNCTLDEYFEPQCEC 412
P+ + + C G +G LC + N C H NCT+ C C
Sbjct: 1159 PPEKLCDGSDD---CGDGSDEGELCDQCSLNNGGCSH--NCTVAPGEGIVCSC 1206
Score = 69.3 bits (168), Expect = 1e-09
Identities = 56/187 (29%), Positives = 78/187 (40%), Gaps = 18/187 (9%)
Frame = -1
Query: 3858 CTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDEL-----NCEITSCKPDFFACFNGTAIS 3694
C+ QF C D+ CI CD EKDC DGSDE +++ C+P+ C GT +
Sbjct: 29 CSPKQFACKDQITCISKGWRCDGEKDCPDGSDESPDICPQSKVSRCQPNEHNCL-GTEL- 86
Query: 3693 KCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQCDGTLD----- 3529
CI C+G DC +G DE C + CT+ C + C TL
Sbjct: 87 -CIHMSKLCNGLHDCFDGSDEGP------HCREQLANCTALGC---QHHCVPTLSGPACY 136
Query: 3528 CRD----GSDEKGCK--KECAI--VCDNSCVHADDLCDGKKKCNDGSDEDEEACVIKQLL 3373
C + D + CK EC + C +C + +G C +CV LL
Sbjct: 137 CNNSFQLAEDRRSCKDFDECTVYGTCSQTCTNT----EGSYTC---------SCVEGYLL 183
Query: 3372 EKENRKC 3352
+ +NR C
Sbjct: 184 QPDNRSC 190
Score = 66.6 bits (161), Expect = 8e-09
Identities = 77/306 (25%), Positives = 120/306 (39%), Gaps = 8/306 (2%)
Frame = -1
Query: 2820 GVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQV 2641
G C+Q C + C C GY+ K+ + CE + + G R + N +
Sbjct: 1851 GDCSQLCLPTSETSRSCMCTAGYS-LKSGQQSCEGVGSFLLYSVHEGIRGIPLD-PNDKS 1908
Query: 2640 SVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEES 2461
L PV + + GIDF + +Y V +G S + R+K+ +W E+
Sbjct: 1909 DALVPVSGTSLAV---GIDFHAE---NDTIYWVDMGLSTIS-RAKRDQ-----TWREDVV 1956
Query: 2460 TAGL-----ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTI 2296
T G+ I D++ N+Y+T+ FD I VA+ + +I
Sbjct: 1957 TNGIGRVEGIAVDWIAGNIYWTDQG-------FDV---IEVARLNGSFRYVVISQGLDKP 2006
Query: 2295 NSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVL 2116
++ V P K +FWT PRI + LDG LV +I P + +
Sbjct: 2007 RAITVHPEKGYLFWTEWGQYPRIERSRLDGTE-----------RMVLVNVSISWPNGISV 2055
Query: 2115 DFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITR---QGS 1945
D+ + +LYW D IE + + + R V ++ V YIY R GS
Sbjct: 2056 DYEDGKLYWCDARTDKIERIDLETGENREVVLSSDNMDMFSVSVFEDYIYWSDRTHANGS 2115
Query: 1944 IHRMHK 1927
I R K
Sbjct: 2116 IKRGSK 2121
Score = 58.9 bits (141), Expect = 2e-06
Identities = 36/89 (40%), Positives = 45/89 (50%), Gaps = 5/89 (5%)
Frame = -1
Query: 6444 ESNCTCNENEFRCQSG-ACIPSKARCNHMQDCNDASDEIG--CPFRNCSAL--NEFGMTG 6280
E+ TC+ +F C+ CI RC+ +DC D SDE CP S NE
Sbjct: 24 EAPKTCSPKQFACKDQITCISKGWRCDGEKDCPDGSDESPDICPQSKVSRCQPNEH---- 79
Query: 6279 LINCATTSQCIHPSWKCDGTNDCYDGSDE 6193
NC T CIH S C+G +DC+DGSDE
Sbjct: 80 --NCLGTELCIHMSKLCNGLHDCFDGSDE 106
Score = 57.0 bits (136), Expect = 6e-06
Identities = 75/390 (19%), Positives = 142/390 (36%), Gaps = 11/390 (2%)
Frame = -1
Query: 2820 GVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQV 2641
G C+ C + +N T C C P + D C K L+ +E V
Sbjct: 1545 GPCSHLCLINYNRTLSCAC-PHLMKLDKDNTTCYEFKKFL---------LYARQMEIRGV 1594
Query: 2640 SVLRPVFNIKMNLIPGGID----FGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWG 2473
+ P +N ++ ID YD + ++ D+R++ I G
Sbjct: 1595 DIDNPYYNYIISFTVPDIDNVTVVDYDAVEQRIYWS--------DVRTQTIKRAFINGTG 1646
Query: 2472 EEE------STAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVN 2311
E A ++ D++ N+++T S + N+ +Q N+ D S + ++
Sbjct: 1647 VETVVSADLPNAHGLSVDWVSRNLFWT-SYDTNK-----KQINV---ARLDGSFKNAVIQ 1697
Query: 2310 STGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEP 2131
+ L V P+ ++WT I AN+DG ++ L+ N P
Sbjct: 1698 GLDKPHCLVVHPLHGKLYWTDG---DNISVANMDGS------------NRTLLFTNQRGP 1742
Query: 2130 TSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVT-MDVLGGYIYLITR 1954
+ +D+ +LYWI TI + DG D + + + T + ++G ++ +
Sbjct: 1743 VGLAIDYPESKLYWISSGNGTINRCNLDGSDLEVIVAVKSQLSKATALAIMGDKLWWADQ 1802
Query: 1953 QGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNTV 1774
+ RM K V +R + + + + S NPC + + +
Sbjct: 1803 --ASERMGTCNKKDGTEVTVLRNSTTLVMLMKVYDE----SIQQAGSNPCSVNNGDCSQL 1856
Query: 1773 CVPDQDKNGILIPKCLCGPGRFFEVSTKKC 1684
C+P + + C+C G + + C
Sbjct: 1857 CLPTSETS----RSCMCTAGYSLKSGQQSC 1882
Score = 48.1 bits (113), Expect = 0.003
Identities = 54/192 (28%), Positives = 64/192 (33%), Gaps = 20/192 (10%)
Frame = -1
Query: 4134 CKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPP----FPCIAGQFVCGRT 3967
C P F C CIS WR E CP P I Q R
Sbjct: 29 CSPKQFACKDQITCISKGWRCDG--------------EKDCPDGSDESPDICPQSKVSRC 74
Query: 3966 AQN-----ATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKC---GDKKKCIP 3811
N T C++ SKLC+G+ DC G DE P C E C G + C+P
Sbjct: 75 QPNEHNCLGTELCIHMSKLCNGLHDCFDGSDEGP------HCREQLANCTALGCQHHCVP 128
Query: 3810 LTS--VCDKEKDCDDGSDELNCEITSCKPDFFAC-FNGTAISKCIPKE--FYCDGEDDCP 3646
S C D +C+ DF C GT C E + C C
Sbjct: 129 TLSGPACYCNNSFQLAEDRRSCK------DFDECTVYGTCSQTCTNTEGSYTC----SCV 178
Query: 3645 EG---QDEPDSC 3619
EG Q + SC
Sbjct: 179 EGYLLQPDNRSC 190
Score = 42.4 bits (98), Expect = 0.15
Identities = 30/94 (31%), Positives = 43/94 (44%), Gaps = 13/94 (13%)
Frame = -1
Query: 6543 RVCRPGYFNCGNGL-CIPEQKVCNRINDCANFADESNCTCNENEF-RCQ--------SGA 6394
+ C P F C + + CI + C+ DC + +DES C +++ RCQ +
Sbjct: 27 KTCSPKQFACKDQITCISKGWRCDGEKDCPDGSDESPDICPQSKVSRCQPNEHNCLGTEL 86
Query: 6393 CIPSKARCNHMQDCNDASDE---IGCPFRNCSAL 6301
CI CN + DC D SDE NC+AL
Sbjct: 87 CIHMSKLCNGLHDCFDGSDEGPHCREQLANCTAL 120
Score = 40.0 bits (92), Expect = 0.77
Identities = 37/129 (28%), Positives = 54/129 (41%), Gaps = 11/129 (8%)
Frame = -1
Query: 6537 CRPGYFNC-GNGLCIPEQKVCNRINDCANFADE--------SNCTCNENEFRCQSGACIP 6385
C+P NC G LCI K+CN ++DC + +DE +NCT CQ C+P
Sbjct: 74 CQPNEHNCLGTELCIHMSKLCNGLHDCFDGSDEGPHCREQLANCTA----LGCQH-HCVP 128
Query: 6384 --SKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDGTNDC 6211
S C CN+ S ++ R+C +E + G C+ T S+ C
Sbjct: 129 TLSGPACY----CNN-SFQLAEDRRSCKDFDECTVYG--TCSQTCTNTEGSYTCSCVEGY 181
Query: 6210 YDGSDEKDC 6184
D + C
Sbjct: 182 LLQPDNRSC 190
>gi|15825005|gb|AAL09566.1| lipoprotein receptor-related protein [Mus
musculus]
Length = 4545
Score = 860 bits (2222), Expect = 0.0
Identities = 623/2001 (31%), Positives = 879/2001 (43%), Gaps = 161/2001 (8%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCT---CNENEFRCQS 6400
DE YC++R C+ + C NG C+ CN ++DC + +DE C C EFRC+
Sbjct: 2556 DEKPSYCNSRRCKKTFRQCNNGRCVSNMLWCNGVDDCGDGSDEIPCNKTACGVGEFRCRD 2615
Query: 6399 GACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLI--NCATTSQCIHPSWKCD 6226
G+CI + +RCN DC DASDE+ C +CS+ G+ G++ C TS C PSW CD
Sbjct: 2616 GSCIGNSSRCNQFVDCEDASDEMNCSATDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCD 2675
Query: 6225 GTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCAD 6046
G NDC D SDE+DC V PR FAC + R C+P W CD + DC +
Sbjct: 2676 GANDCGDYSDERDC--------PGVKRPRC--PLNYFACPSGR-CIPMSWTCDKEDDCEN 2724
Query: 6045 GSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKG-GNAT 5869
G DE +C+ K C+ +F C++ + CI + CDG DC DG DE C+ K G ++
Sbjct: 2725 GEDETHCN-KFCSEAQFECQNHR-CISKQWLCDGSDDCGDGSDE---AAHCEGKTCGPSS 2779
Query: 5868 FRCTN-HRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACEL 5692
F C H C+P W CDG DC D A S C T C + C+
Sbjct: 2780 FSCPGTHVCVPERWLCDGDKDCTDGADE--SVTAGCLYNSTCDDREFMCQNRLCIPK--- 2834
Query: 5691 TAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRL-CDASVDCVDGSDEW 5515
+CD +DC+DG DE C PNE+ C +G+C+ S + CD DC D SDE
Sbjct: 2835 -HFVCDHDRDCADGSDESPECEYPT-CGPNEFRCANGRCLSSRQWECDGENDCHDHSDEA 2892
Query: 5514 VEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSST 5335
+ + P + C + L ++G C+ E LC+G+ DC G DE+ + S
Sbjct: 2893 PKNPHCTSPEHK-CNASSQFLCSSGR--CVAEALLCNGQDDCGDGSDERGCHVNECLSRK 2949
Query: 5334 RNSCDQTWNCQR-HAGFESCSCDDGYHLSPYDKKTCLRSPSCPKA-NCSHFCIDRRDVGH 5161
+ C Q +C+ GF+ C C G+ L D +TC C CS CI+ +
Sbjct: 2950 LSGCSQ--DCEDLKIGFK-CRCRPGFRLKD-DGRTCADLDECSTTFPCSQLCINTHG-SY 3004
Query: 5160 QCFCAPGYI-LSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLTNGVALD 4984
+C C GY + C+ E ++ + L+ +DG L L N VALD
Sbjct: 3005 KCLCVEGYAPRGGDPHSCKAVTDEEPFLIFANRYYLRKLNLDGSNYTLLKQGLNNAVALD 3064
Query: 4983 YDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDR 4804
+D + ++YWTDV G+ I M + +V++ DG+AVDW+G N+Y+ D+
Sbjct: 3065 FDYREQMIYWTDVTTQGSM--IRRMHLNGSNVQVLHRTGLSNPDGLAVDWVGGNLYWCDK 3122
Query: 4803 NHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNE 4624
D I V + G + +L+ + L +PRA+V+D ++WTDWG + IGR+ MDGS
Sbjct: 3123 GRDTIEVSKLNGAYRTVLVS-SGLREPRALVVDVQNGYLYWTDWGDHSLIGRIGMDGSGR 3181
Query: 4623 QVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAV 4444
+I+ D I WPN L VD +R+Y+ DA DYI + DGS R +VL + HIFAL +
Sbjct: 3182 SIIV-DTKITWPNGLTVDYVTERIYWADAREDYIEFASLDGSNRHVVLSQDIPHIFALTL 3240
Query: 4443 FEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPC 4264
FEDYVYW+DW +I R HK TG N+ +LI +RPM + H Q HPC
Sbjct: 3241 FEDYVYWTDWETKSINRAHKTTGANKTLLISTL-HRPMDLHVFHALRQP----DVPNHPC 3295
Query: 4263 S-QPARCDNLCIPANTPDLTTSSDNFTCMCAQGFR--SEGRSCVSECKPNDFVCTKTYKC 4093
C NLC L + C C F +GR+CVS C + FVC K KC
Sbjct: 3296 KVNNGGCSNLC-------LLSPGGGHKCACPTNFYLGGDGRTCVSNCTASQFVC-KNDKC 3347
Query: 4092 ISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGV 3913
I WW+ CP F C GQF C +T C + +CDG
Sbjct: 3348 IPFWWKCDTEDDCGDHSDE----PPDCPEFKCRPGQFQC------STGICTNPAFICDGD 3397
Query: 3912 KDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCK 3733
DC DE A C+ C +QFKC + +CIP C+ + +C DG DE +C +C
Sbjct: 3398 NDCQDNSDE--ANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTCA 3455
Query: 3732 PDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCT-SGKCIPK 3556
P+ F C + +CIP+ + CD ++DC +G DEP +C + C ++F+C SG+CIP
Sbjct: 3456 PNQFQC---SITKRCIPRVWVCDRDNDCVDGSDEPANCTQM-TCGVDEFRCKDSGRCIPA 3511
Query: 3555 RRQCDGTLDCRDGSDEKGCKKEC-AIVCD--------NSCVHADDLCDGKKKCNDGSDED 3403
R +CDG DC DGSDE K+EC C+ N CV CD C D SDE
Sbjct: 3512 RWKCDGEDDCGDGSDEP--KEECDERTCEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDE- 3568
Query: 3402 EEACVIKQLLEKE----NRKC--GGFACDGIVDCEDGSDEKGCP---DLECHLASNKSLI 3250
E+C + E E N +C G + CDG DC DGSDEK C D++ + I
Sbjct: 3569 -ESCTPRPCSESEFSCANGRCIAGRWKCDGDHDCADGSDEKDCTPRCDMDQFQCKSGHCI 3627
Query: 3249 -----CDGTIDCSSGKDENNCHNNGES---NFFQCSMQTIKE--WQVCDGRWDCADGLDE 3100
CD DC G DE C + + FQC+ K W+ CDG DC D DE
Sbjct: 3628 PLRWRCDADADCMDGSDEEACGTGVRTCPLDEFQCNNTLCKPLAWK-CDGEDDCGDNSDE 3686
Query: 3099 SPEMCA------SRKARCFR------IG--------------------------YCDDKK 3034
+PE CA +R RC IG +C DKK
Sbjct: 3687 NPEECARFICPPNRPFRCKNDRVCLWIGRQCDGVDNCGDGTDEEDCEPPTAQNPHCKDKK 3746
Query: 3033 Q-------CLDVSTALCDGIRDCFDGSDENPIHCK----------DMCKGKYRCTNGRCI 2905
+ CL S+ C+ DC DGSDE MC + RC
Sbjct: 3747 EFLCRNQRCLS-SSLRCNMFDDCGDGSDEEDCSIDPKLTSCATNASMCGDEARCVRTEKA 3805
Query: 2904 DVSARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTAR---CHCAPGYARTKND 2734
A EC FG C+Q C N+T C CA + +T
Sbjct: 3806 AYCACRSGFHTVPGQPGCQDIN-ECLRFGTCSQLC----NNTKGGHLCSCARNFMKT--- 3857
Query: 2733 ENECEPLSKSAE-MFITNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRT- 2560
N C+ + ++I + N + + S F ++ +D R
Sbjct: 3858 HNTCKAEGSEYQVLYIADDNEIRSL-FPGHPHSAYEQTFQGDESVRIDAMDVHVKAGRVY 3916
Query: 2559 -TLMYTVGIGNSRVDIRSKKWSDGL----IGSWGEEESTAGL-----ITYDFMHNNVYFT 2410
T +T I + + + I + +GL I D++ NVY+T
Sbjct: 3917 WTNWHTGTISYRSLPPAAPPTTSNRHRRQIDRGVTHLNISGLKMPRGIAIDWVAGNVYWT 3976
Query: 2409 ESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPR 2230
+S I VA+ K + +TLI +++ VDP++ ++W+ P+
Sbjct: 3977 DSGRDV----------IEVAQMKGENRKTLISGMIDEPHAIVVDPLRGTMYWSDWGNHPK 4026
Query: 2229 ILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSF 2050
I +A +DG + LV+ NI PT + +D+ NERLYW D I ++
Sbjct: 4027 IETAAMDGTL-----------RETLVQDNIQWPTGLAVDYHNERLYWADAKLSVIGSIRL 4075
Query: 2049 DGRDRRTVRKFELG-DTPVTMDVLGGYIYLITR-QGSIHRMHKFTGKTNKYVQKIREVSP 1876
+G D + G P ++DV YIY +T + ++HKF SP
Sbjct: 4076 NGTDPIVAADSKRGLSHPFSIDVFEDYIYGVTYINNRVFKIHKFGH------------SP 4123
Query: 1875 RIQIR--VAHPAKHTVSHITHQK---NPCQSDYCPSNTVCVPDQDKNGILIPKCLCGPGR 1711
I + ++H + + H Q NPC C + P P C C G+
Sbjct: 4124 LINLTGGLSHASDVVLYHQHKQPEVTNPCDRKKCEWLCLLSPSG-------PVCTCPNGK 4176
Query: 1710 FFEVSTKKCMQLREKDQEASQCGDYF--CYNNAGC----SPQKTCVCPPGFYGRQCEINE 1549
+ T + +A + G C+N C Q C C P + G +CE+++
Sbjct: 4177 RLDNGTCVPVPSPTPPPDAPRPGTCTLQCFNGGSCFLNARRQPKCRCQPRYTGDKCELDQ 4236
Query: 1548 CSETCWNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEP 1369
C E C NG TCA G T C CP+ +T C VC G C +C ++P
Sbjct: 4237 CWEYCHNGGTCAASPSGMPT---CRCPTGFTGPKCTAQVCAGYCSNNSTCTV--NQGNQP 4291
Query: 1368 HCRSYSFCECDKGWTGPHCRHKADAKVCYGHCFSGGAC----DG----------EGPL-- 1237
CR C G+ G C+++ C G C + G C DG EGP
Sbjct: 4292 QCR------CLPGFLGDRCQYRQ----CSGFCENFGTCQMAADGSRQCRCTVYFEGPRCE 4341
Query: 1236 -------------------NLRCSCGDGLTGNRCQNCVGHECLNGGFCSYANSNRSLPHC 1114
++ C+C DG C C+ H C NGG C+ +++ +P C
Sbjct: 4342 VNKCSRCLQGACVVNKQTGDVTCNCTDGRVAPSCLTCIDH-CSNGGSCTM--NSKMMPEC 4398
Query: 1113 ICPSGFTGDHCEEYLCKDACP 1051
CP TG CEE + P
Sbjct: 4399 QCPPHMTGPRCEEQVVSQQQP 4419
Score = 375 bits (962), Expect = e-101
Identities = 312/1088 (28%), Positives = 441/1088 (39%), Gaps = 83/1088 (7%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGN-GLCIPEQKVCNRINDCANFADESNC---TCNENEFRC 6406
D+ D C VC P F C N CIP CN ++C + DE +C TC N+F+C
Sbjct: 3402 DNSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTCAPNQFQC 3461
Query: 6405 Q-SGACIPSKARCNHMQDCNDASDE-IGCPFRNCSALNEFGMTGLINCATTSQCIHPSWK 6232
+ CIP C+ DC D SDE C C ++EF C + +CI WK
Sbjct: 3462 SITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTC-GVDEF------RCKDSGRCIPARWK 3514
Query: 6231 CDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKT----QFACLATRTCMPKHWQCDG 6064
CDG +DC DGSDE CD +T QF C R C+P WQCD
Sbjct: 3515 CDGEDDCGDGSDE---------------PKEECDERTCEPYQFRCKNNR-CVPGRWQCDY 3558
Query: 6063 QPDCADGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSK 5884
DC D SDE++C + C+ EFSC ++ +CI KCDG DC DG DE C CD
Sbjct: 3559 DNDCGDNSDEESCTPRPCSESEFSC-ANGRCIAGRWKCDGDHDCADGSDEKDCTPRCDMD 3617
Query: 5883 GGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVV 5704
F+C + CIP+ WRCD DCMD GSDE C G + + + T
Sbjct: 3618 ----QFQCKSGHCIPLRWRCDADADCMD-----GSDEEACGTGVRTCPLDEFQCNNT--- 3665
Query: 5703 ACELTAVLCDGIQDCSDGFDE--KNCASLDRQCKPNE-WMCDSGQ-CIDSGRLCDASVDC 5536
C+ A CDG DC D DE + CA C PN + C + + C+ GR CD +C
Sbjct: 3666 LCKPLAWKCDGEDDCGDNSDENPEECARF--ICPPNRPFRCKNDRVCLWIGRQCDGVDNC 3723
Query: 5535 VDGSDEWVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQ---C 5365
DG+DE E C C L N CL C+ DC G DE+
Sbjct: 3724 GDGTDE--EDCEPPTAQNPHCKDKKEFLCRNQR--CLSSSLRCNMFDDCGDGSDEEDCSI 3779
Query: 5364 DNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSP-----YDKKTCLRSPSCPKAN 5200
D +C++ + C C R C+C G+H P D CLR
Sbjct: 3780 DPKLTSCATNASMCGDEARCVRTEKAAYCACRSGFHTVPGQPGCQDINECLRF-----GT 3834
Query: 5199 CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKAT 5020
CS C + + GH C CA ++ + N C+ + E ++L + GH +
Sbjct: 3835 CSQLCNNTKG-GHLCSCARNFMKTHN--TCKAEGS-EYQVLYIADDNEIRSLFPGHPHSA 3890
Query: 5019 LLSNLTNGV-----ALDYDVKSDLVYWTDVAHDGN---------KAGITSMSNQPNTYRV 4882
A+D VK+ VYWT+ H G TS ++ R
Sbjct: 3891 YEQTFQGDESVRIDAMDVHVKAGRVYWTN-WHTGTISYRSLPPAAPPTTSNRHRRQIDRG 3949
Query: 4881 INSLPTKGID---GIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIV 4711
+ L G+ GIA+DW+ N+Y+TD D I V M+G + L+ G +++P AIV
Sbjct: 3950 VTHLNISGLKMPRGIAIDWVAGNVYWTDSGRDVIEVAQMKGENRKTLISGM-IDEPHAIV 4008
Query: 4710 LDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHR 4531
+DPL+ ++W+DWG I MDG+ + ++QD I+WP LAVD +RLY+ DA
Sbjct: 4009 VDPLRGTMYWSDWGNHPKIETAAMDGTLRETLVQD-NIQWPTGLAVDYHNERLYWADAKL 4067
Query: 4530 DYIASCNYDGSKRRMVL--RGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVL 4357
I S +G+ + + + H F++ VFEDY+Y + N+ + ++HK G + +
Sbjct: 4068 SVIGSIRLNGTDPIVAADSKRGLSHPFSIDVFEDYIYGVTYINNRVFKIHKF-GHSPLIN 4126
Query: 4356 IQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDNLCIPANTPDLTTSSDNFTCMC 4177
+ + H Q +PC + +C+ LC+ S C C
Sbjct: 4127 LTGGLSHASDVVLYHQHKQ-----PEVTNPCDR-KKCEWLCL--------LSPSGPVCTC 4172
Query: 4176 AQGFRSEGRSCV---SECKPND--------FVCTKTYKCISSWWRXXXXXXXXXXXXXGY 4030
G R + +CV S P D C C + R
Sbjct: 4173 PNGKRLDNGTCVPVPSPTPPPDAPRPGTCTLQCFNGGSCFLNARRQPKCRCQPRYTGDKC 4232
Query: 4029 FVE---------GVCPPFPCIAGQFVC----GRTAQNATAQCLYASKLCDGVKDCSGGDD 3889
++ G C P +G C G T TAQ + C C+
Sbjct: 4233 ELDQCWEYCHNGGTCAASP--SGMPTCRCPTGFTGPKCTAQ--VCAGYCSNNSTCTVNQG 4288
Query: 3888 EEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCD---DGSDEL---------NCEI 3745
+P +C GD+ + + C+ C DGS + CE+
Sbjct: 4289 NQP------QCRCLPGFLGDRCQYRQCSGFCENFGTCQMAADGSRQCRCTVYFEGPRCEV 4342
Query: 3744 TSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEP------DSCFGIGECTHEQFQ 3583
C C G C+ + D +C +G+ P D C G CT
Sbjct: 4343 NKCS----RCLQGA----CVVNKQTGDVTCNCTDGRVAPSCLTCIDHCSNGGSCTMNSKM 4394
Query: 3582 CTSGKCIP 3559
+C P
Sbjct: 4395 MPECQCPP 4402
Score = 369 bits (946), Expect = e-100
Identities = 259/818 (31%), Positives = 354/818 (42%), Gaps = 38/818 (4%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCI--PEQKVCNRINDCANFADESNCT----------C 6427
D + T CR C + LC+ P + C D D C C
Sbjct: 797 DAQQQQVGTNKCRVNNGGCSS-LCLATPGSRQCACAEDQVLDTDGVTCLANPSYVPPPQC 855
Query: 6426 NENEFRCQSGACIPSKARCNHMQDCNDASDEIG--CPFRNCSALNEFGMTGLINCATTSQ 6253
EF C + CI + +C+ DC D SDE C C + C ++
Sbjct: 856 QPGEFACANNRCIQERWKCDGDNDCLDNSDEAPALCHQHTCPS-------DRFKCEN-NR 907
Query: 6252 CIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKT----QFACLATRTCMP 6085
CI W CDG NDC + DE + +C A+T QF+C + R C+P
Sbjct: 908 CIPNRWLCDGDNDCGNSEDESNA---------------TCSARTCPPNQFSCASGR-CIP 951
Query: 6084 KHWQCDGQPDCADGSDEK-NCDAKKCTSF-EFSCESSKKCIPLEQKCDGRRDCPDGEDEH 5911
W CD DC D SDE +C C +F+C + + CI + +CD DC D DE
Sbjct: 952 ISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNGR-CININWRCDNDNDCGDNSDEA 1010
Query: 5910 QCETECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPS 5731
C C S F+C + RCIP W CDG +DC D SDE + P
Sbjct: 1011 GCSHSCSS----TQFKCNSGRCIPEHWTCDGDNDCGDY-----SDETHANCTNQATRPPG 1061
Query: 5730 RCADETCVVACELTAVL------CDGIQDCSDGFDEKNCASLDRQCKPN-EWMC-DSGQC 5575
C + C L + CDG DC D DEK+C + C PN ++ C DS +C
Sbjct: 1062 GCHSDE--FQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPNVKFGCKDSARC 1119
Query: 5574 IDSGRLCDASVDCVDGSDEWVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRR 5395
I +CD DC D SDE PP C N T CL +LCDG+
Sbjct: 1120 ISKAWVCDGDSDCEDNSDEENCEALACRPPSHPC--------ANNTSVCLPPDKLCDGKD 1171
Query: 5394 DCMSGIDEQ--CDNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRS 5221
DC G DE CD CS C + G CSC G L D TC
Sbjct: 1172 DCGDGSDEGELCDQ----CSLNNGGCSHNCSVAPGEGIV-CSCPLGMELGS-DNHTCQIQ 1225
Query: 5220 PSCPK-ANCSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFT 5044
C K CS C D+ +C C G++L + + CR D + I+ H ++
Sbjct: 1226 SYCAKHLKCSQKC-DQNKFSVKCSCYEGWVLEPDGESCRSLDPFKPFIIFSNRHEIRRID 1284
Query: 5043 IDGHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPT 4864
+ + L+ L N +ALD+ + +YWTDV D G + ++ V+
Sbjct: 1285 LHKGDYSVLVPGLRNTIALDFHLSQSALYWTDVVEDKIYRGKLLDNGALTSFEVVIQYGL 1344
Query: 4863 KGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVF 4684
+G+AVDW+ NIY+ + N D I V + G LL G + PRAI LDP ++F
Sbjct: 1345 ATPEGLAVDWIAGNIYWVESNLDQIEVAKLDGTLRTTLLAG-DIEHPRAIALDPRDGILF 1403
Query: 4683 WTDWGAS-AHIGRMNMDGSNEQVILQDR-TIRWPNALAVDAPAQRLYFGDAHRDYIASCN 4510
WTDW AS I +M G+ + I ++ + WPN L VD +R+ + DA D I S
Sbjct: 1404 WTDWDASLPRIEAASMSGAGRRTIHRETGSGGWPNGLTVDYLEKRILWIDARSDAIYSAR 1463
Query: 4509 YDGSKRRMVLRGS--VRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYR 4336
YDGS VLRG + H FA+ ++ VYW+DW +T+ + +K TG N V +Q +
Sbjct: 1464 YDGSGHMEVLRGHEFLSHPFAVTLYGGEVYWTDWRTNTLAKANKWTGHNVTV-VQRTNTQ 1522
Query: 4335 PMGFKIVHPSLQSMGSLKTARHPCSQ---PARCDNLCI 4231
P ++ HPS Q M A +PC C +LC+
Sbjct: 1523 PFDLQVYHPSRQPM-----APNPCEANGGRGPCSHLCL 1555
Score = 367 bits (942), Expect = 2e-99
Identities = 456/1851 (24%), Positives = 691/1851 (36%), Gaps = 225/1851 (12%)
Frame = -1
Query: 5214 CPKAN--CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTI 5041
C AN C C+ R C CA G +L+E+ CR E ++Y R L +I
Sbjct: 2160 CAVANGGCQQLCLYRGGGQRACACAHG-MLAEDGASCR-----EYAGYLLYSERTILKSI 2213
Query: 5040 DGHAKATLLS---------NLTNGVALDYDVKS-------DLVYWTDVAHDGNKAGITSM 4909
+ L + ++ N +AL +D ++ + ++++D+ H GN I
Sbjct: 2214 HLSDERNLNAPVQPFEDPEHMKNVIALAFDYRAGTSPGTPNRIFFSDI-HFGNIQQINDD 2272
Query: 4908 SNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIA---VCDMR-GRFNR---IL 4750
+ T ++ ++ + ++G+A +Y+T I V R G F R I
Sbjct: 2273 GSGRTT--IVENVGS--VEGLAYHRGWDTLYWTSYTTSTITRHTVDQTRPGAFERETVIT 2328
Query: 4749 LKGTPLNDPRAIVLDPLQALVFWTDWGA-SAHIGRMNMDGSNEQVILQDRTIRWPNALAV 4573
+ G + PRA VLD Q L+FWT+W I R + G+N +++ + IR PN LA+
Sbjct: 2329 MSGD--DHPRAFVLDECQNLMFWTNWNELHPSIMRAALSGANVLTLIE-KDIRTPNGLAI 2385
Query: 4572 DAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIER 4393
D A++LYF DA D I C YDGS R ++L+ H F LAV+ ++++W+DW ++R
Sbjct: 2386 DHRAEKLYFSDATLDKIERCEYDGSHRYVILKSEPVHPFGLAVYGEHIFWTDWVRRAVQR 2445
Query: 4392 VHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCS-QPARCDNLCIPANTP 4216
+K G++ K+L D +PMG V S PC C +LC
Sbjct: 2446 ANKYVGSDMKLLRVDIPQQPMGIIAVANDTNSC-----ELSPCRINNGGCQDLC------ 2494
Query: 4215 DLTTSSDNFTCMCAQG-FRSEGRSCV---SECKPNDFVCTKTYKCISSWWRXXXXXXXXX 4048
L T + C C G E +C S C+ D +CIS
Sbjct: 2495 -LLTHQGHVNCSCRGGRILQEDFTCRAVNSSCRAQDEFECANGECIS----------FSL 2543
Query: 4047 XXXXGYFVEGVCPPFPCIAGQFVCGRTAQNAT-AQCLYASKLCDGVKDCSGGDDEEPAFC 3871
+ P C +T + +C+ C+GV DC G DE P C
Sbjct: 2544 TCDGVSHCKDKSDEKPSYCNSRRCKKTFRQCNNGRCVSNMLWCNGVDDCGDGSDEIP--C 2601
Query: 3870 ENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCKPDFFACFNGTAI-- 3697
C +F+C D CI +S C++ DC+D SDE+NC T C F G
Sbjct: 2602 NKTACGVGEFRCRDGS-CIGNSSRCNQFVDCEDASDEMNCSATDCSSYFRLGVKGVLFQP 2660
Query: 3696 ----SKCIPKEFYCDGEDDCPEGQDEPDSCFGIGE--CTHEQFQCTSGKCIPKRRQCDGT 3535
S C + CDG +DC + DE D C G+ C F C SG+CIP CD
Sbjct: 2661 CERTSLCYAPSWVCDGANDCGDYSDERD-CPGVKRPRCPLNYFACPSGRCIPMSWTCDKE 2719
Query: 3534 LDCRDGSDEKGCKKECA---IVCDNS-CVHADDLCDGKKKCNDGSDEDEEACVIKQLLEK 3367
DC +G DE C K C+ C N C+ LCDG C DGSDE
Sbjct: 2720 DDCENGEDETHCNKFCSEAQFECQNHRCISKQWLCDGSDDCGDGSDEAAHC--------- 2770
Query: 3366 ENRKCGG---------------FACDGIVDCEDGSDEK---------GCPDLEC----HL 3271
E + CG + CDG DC DG+DE C D E L
Sbjct: 2771 EGKTCGPSSFSCPGTHVCVPERWLCDGDKDCTDGADESVTAGCLYNSTCDDREFMCQNRL 2830
Query: 3270 ASNKSLICDGTIDCSSGKDEN-NC-HNNGESNFFQCS---MQTIKEWQVCDGRWDCADGL 3106
K +CD DC+ G DE+ C + N F+C+ + ++W+ CDG DC D
Sbjct: 2831 CIPKHFVCDHDRDCADGSDESPECEYPTCGPNEFRCANGRCLSSRQWE-CDGENDCHDHS 2889
Query: 3105 DESPEM--CASRKARCFRIG-YCDDKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKG 2935
DE+P+ C S + +C + +C+ LC+G DC DGSDE H +
Sbjct: 2890 DEAPKNPHCTSPEHKCNASSQFLCSSGRCV-AEALLCNGQDDCGDGSDERGCHVNECLSR 2948
Query: 2934 KYRCTNGRCIDVS----ARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCH 2767
K + C D+ R EC C+Q C + + + +C
Sbjct: 2949 KLSGCSQDCEDLKIGFKCRCRPGFRLKDDGRTCADLDECSTTFPCSQLC-INTHGSYKCL 3007
Query: 2766 CAPGYARTKNDENECEPLSKSAEMFITNGNRLHL--MSLENSQVSVLRPVFNIKMNLIPG 2593
C GYA D + C+ ++ E F+ NR +L ++L+ S ++L+ N + L
Sbjct: 3008 CVEGYAPRGGDPHSCKAVTDE-EPFLIFANRYYLRKLNLDGSNYTLLKQGLNNAVAL--- 3063
Query: 2592 GIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGL-----ITYDFMH 2428
DF Y R ++Y + IR L GS + GL + D++
Sbjct: 3064 --DFDY---REQMIYWTDVTTQGSMIRRMH----LNGSNVQVLHRTGLSNPDGLAVDWVG 3114
Query: 2427 NNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTT 2248
N+Y+ + I V+K L+ + +L VD ++WT
Sbjct: 3115 GNLYWCDKGRDT----------IEVSKLNGAYRTVLVSSGLREPRALVVDVQNGYLYWTD 3164
Query: 2247 SAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRT 2068
I +DG +V+ I P + +D+ ER+YW D +
Sbjct: 3165 WGDHSLIGRIGMDGSG-----------RSIIVDTKITWPNGLTVDYVTERIYWADAREDY 3213
Query: 2067 IETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGK-------- 1915
IE S DG +R V ++ + + Y+Y SI+R HK TG
Sbjct: 3214 IEFASLDGSNRHVVLSQDIPHI-FALTLFEDYVYWTDWETKSINRAHKTTGANKTLLIST 3272
Query: 1914 -------------------------TNKYVQKIREVSPRIQIRVAHP--------AKHTV 1834
N + +SP + A P + V
Sbjct: 3273 LHRPMDLHVFHALRQPDVPNHPCKVNNGGCSNLCLLSPGGGHKCACPTNFYLGGDGRTCV 3332
Query: 1833 SHITHQKNPCQSDYC-PSNTVCVPDQDKNGIL-----IPKCLCGPGRFFEVSTKKCMQLR 1672
S+ T + C++D C P C + D P+ C PG+ F+ ST C
Sbjct: 3333 SNCTASQFVCKNDKCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQ-FQCSTGIC---- 3387
Query: 1671 EKDQEASQC-GDYFCYNNAGCSPQKTCVCPPGFYGRQCEINEC---------SETCWNGE 1522
A C GD C +N+ + VC P + + N C + C +GE
Sbjct: 3388 --TNPAFICDGDNDCQDNSDEANCDIHVCLPSQF-KCTNTNRCIPGIFRCNGQDNCGDGE 3444
Query: 1521 --------TCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPH 1366
TCA +F + C P + N C +C + C DE
Sbjct: 3445 DERDCPEVTCAPNQFQCSITKRC-IPRVWVCD--RDNDCVDGSDEPANCTQMTCGVDEFR 3501
Query: 1365 CRSYSFC---------ECDKGWTGPHCRHKADAKVCYGH---CFSGGACDGEGPLNLRCS 1222
C+ C E D G + + D + C + C + G +
Sbjct: 3502 CKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCKNNRCVPGRWQCDYDND 3561
Query: 1221 CGDGLTGNRCQ---------NCVGHECLNGGF-------CSYANSNRS-LPHC-----IC 1108
CGD C +C C+ G + C+ + + P C C
Sbjct: 3562 CGDNSDEESCTPRPCSESEFSCANGRCIAGRWKCDGDHDCADGSDEKDCTPRCDMDQFQC 3621
Query: 1107 PSGF---------TGDHCEEYLCKDACPFGSKCTYDITKPMDPITCS---CEQNA--AAH 970
SG C + ++AC G + T P+D C+ C+ A
Sbjct: 3622 KSGHCIPLRWRCDADADCMDGSDEEACGTGVR-----TCPLDEFQCNNTLCKPLAWKCDG 3676
Query: 969 NTDCSPICQKQPNWCHNGGRCLDTPGYPGKCK----CLPRFAGPRCDVPVQCDDYCTNNS 802
DC + P C R + P P +CK CL + G +CD C D T+
Sbjct: 3677 EDDCGDNSDENPEEC---ARFICPPNRPFRCKNDRVCL--WIGRQCDGVDNCGD-GTDEE 3730
Query: 801 KCTITNGTHFECDCKPGF---------KGLRCEQETKCSECSNEAKCIKKPSGTVICQCP 649
C + C K F LRC C + S+E C P
Sbjct: 3731 DCEPPTAQNPHCKDKKEFLCRNQRCLSSSLRCNMFDDCGDGSDEEDCSIDP--------- 3781
Query: 648 QGLGGEYCEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSSNACE-- 475
K+T+ + + C + C++ + +A C C GF + C+
Sbjct: 3782 ---------KLTSCATNASMCGDEARCVRTEKAA-----YCACRSGFH-TVPGQPGCQDI 3826
Query: 474 NFCLHDGNCTL---DEYFEPQCECYQAFI--GDRCQYRIHQHAVIFSDDDS 337
N CL G C+ + C C + F+ + C+ ++ V++ DD+
Sbjct: 3827 NECLRFGTCSQLCNNTKGGHLCSCARNFMKTHNTCKAEGSEYQVLYIADDN 3877
Score = 335 bits (858), Expect = 1e-89
Identities = 308/1243 (24%), Positives = 494/1243 (38%), Gaps = 88/1243 (7%)
Frame = -1
Query: 5259 HLSPYDKKTCLRSPSCPK------ANCSHFCI-DRRDVGHQCFCAPGYILSENQKDCRRN 5101
H+ ++ +RS +C CS C+ C C G+ L + K C++
Sbjct: 464 HIYHQRRQPRVRSHACENDQYGKPGGCSDICLLANSHKARTCRCRSGFSLGSDGKSCKKP 523
Query: 5100 DTIEAEILMVYGHRLK--LFTIDGHAKAT-----LLSNLTNGVALDYDVKSDLVYWTDVA 4942
E E+ +VYG + +D AK + NL N ALD+ ++ +Y+ D
Sbjct: 524 ---EHELFLVYGKGRPGIIRGMDMGAKVPDEHMIPIENLMNPRALDFHAETGFIYFADTT 580
Query: 4941 HDGNKAGITSMSNQPNTYR-VINSLPTKGIDGIAVDWLGRNIYYTD---RNHDAIAVCDM 4774
+ + T R I ++G+AVDW+G N+Y+TD + ++A +
Sbjct: 581 -----SYLIGRQKIDGTERETILKDGIHNVEGVAVDWMGDNLYWTDDGPKKTISVARLEK 635
Query: 4773 RGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDW------GASAHIGRMNMDGSNEQVIL 4612
+ + L++G + PRAIV+DPL ++WTDW + R MDGS+ + +
Sbjct: 636 AAQTRKTLIEGK-MTHPRAIVVDPLNGWMYWTDWEEDPKDSRRGRLERAWMDGSHRDIFV 694
Query: 4611 QDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRG-SVRHIFALAVFED 4435
+T+ WPN L++D PA RLY+ DA D I + +G+ R++V G + H F L +
Sbjct: 695 TSKTVLWPNGLSLDIPAGRLYWVDAFYDRIETILLNGTDRKIVYEGPELNHAFGLCHHGN 754
Query: 4434 YVYWSDWHNHTIERVHK-ITGTNRKVLIQDKQYRPM-GFKIVHPSLQSMGSLKTARHPCS 4261
Y++W+++ + ++ R+ + + G V + + P+ ++ Q +G+ K
Sbjct: 755 YLFWTEYRSGSVYRLERGVAGAPPTVTLLRSERPPIFEIRMYDAQQQQVGTNKCR----V 810
Query: 4260 QPARCDNLCIPANTPDLTTSSDNFTCMCAQGFRSEGRSCVS--------ECKPNDFVCTK 4105
C +LC+ T S C Q ++G +C++ +C+P +F C
Sbjct: 811 NNGGCSSLCL------ATPGSRQCACAEDQVLDTDGVTCLANPSYVPPPQCQPGEFACAN 864
Query: 4104 TYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKL 3925
+CI W+
Sbjct: 865 N-RCIQERWK-------------------------------------------------- 873
Query: 3924 CDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELN--C 3751
CDG DC DE PA C C +FKC + +CIP +CD + DC + DE N C
Sbjct: 874 CDGDNDCLDNSDEAPALCHQHTCPSDRFKC-ENNRCIPNRWLCDGDNDCGNSEDESNATC 932
Query: 3750 EITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSG 3571
+C P+ F+C +G +CIP + CD +DDC + DE SC QF C +G
Sbjct: 933 SARTCPPNQFSCASG----RCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNG 988
Query: 3570 KCIPKRRQCDGTLDCRDGSDEKGCKKECA---IVCDNS-CVHADDLCDGKKKCNDGSDED 3403
+CI +CD DC D SDE GC C+ C++ C+ CDG C D SDE
Sbjct: 989 RCININWRCDNDNDCGDNSDEAGCSHSCSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDET 1048
Query: 3402 EEACVIKQLLEKENRKCGG------------------FACDGIVDCEDGSDEKGCPDL-- 3283
C + R GG + CDG DC D SDEK C +
Sbjct: 1049 HANCT-----NQATRPPGGCHSDEFQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTH 1103
Query: 3282 -----------ECHLASNKSLICDGTIDCSSGKDENNCHNNG-ESNFFQCSMQT---IKE 3148
+ +K+ +CDG DC DE NC C+ T +
Sbjct: 1104 VCDPNVKFGCKDSARCISKAWVCDGDSDCEDNSDEENCEALACRPPSHPCANNTSVCLPP 1163
Query: 3147 WQVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDE 2968
++CDG+ DC DG DE E+C G C +C GSD
Sbjct: 1164 DKLCDGKDDCGDGSDEG-ELCDQCS---LNNGGCSHNCSVAPGEGIVCSCPLGMELGSDN 1219
Query: 2967 NPIHCKDMCKGKYRCTNGRCIDVSARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAF 2788
+ + C + C+QKC
Sbjct: 1220 HTCQIQSYCAKHLK-------------------------------------CSQKCDQN- 1241
Query: 2787 NHTARCHCAPGYARTKNDENECEPLSKSAEMFI-TNGNRLHLMSLENSQVSVLRPVFNIK 2611
+ +C C G+ + D C L I +N + + + L SVL P
Sbjct: 1242 KFSVKCSCYEGWV-LEPDGESCRSLDPFKPFIIFSNRHEIRRIDLHKGDYSVLVPGLR-- 1298
Query: 2610 MNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGLIT---- 2443
N I +DF + +Y + ++ R K +G + S+ E GL T
Sbjct: 1299 -NTI--ALDFH---LSQSALYWTDVVEDKI-YRGKLLDNGALTSF-EVVIQYGLATPEGL 1350
Query: 2442 -YDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKR 2266
D++ N+Y+ ES+ I VAK T TL+ ++A+DP
Sbjct: 1351 AVDWIAGNIYWVESNLD----------QIEVAKLDGTLRTTLLAGDIEHPRAIALDPRDG 1400
Query: 2265 LIFWTT-SAPVPRILSANLDG---KPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNER 2098
++FWT A +PRI +A++ G + I + +G P+ + +D+ +R
Sbjct: 1401 ILFWTDWDASLPRIEAASMSGAGRRTIHRETGSGGWPN------------GLTVDYLEKR 1448
Query: 2097 LYWIDVLKRTIETVSFDGRDRRTV-RKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKF 1924
+ WID I + +DG V R E P + + GG +Y R ++ + +K+
Sbjct: 1449 ILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYGGEVYWTDWRTNTLAKANKW 1508
Query: 1923 TGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSD 1795
TG VQ R + ++V HP++ ++ NPC+++
Sbjct: 1509 TGHNVTVVQ--RTNTQPFDLQVYHPSRQPMA-----PNPCEAN 1544
Score = 203 bits (517), Expect = 4e-50
Identities = 149/518 (28%), Positives = 239/518 (45%), Gaps = 26/518 (5%)
Frame = -1
Query: 5619 RQCKPNEWMC-DSGQCIDSGRLCDASVDCVDGSDEWVEICSLSEPPRRGCPSG-WSCLLT 5446
+ C P ++ C D CI G CD DC DGSDE EIC S+ R CP SCL
Sbjct: 26 KTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQR--CPPNEHSCL-- 81
Query: 5445 NGTIGCLQEQQLCDGRRDCMSGIDE--QCDNPQGNCSSTRNSCDQTWNCQRHAGFESCSC 5272
GT C+ +LC+G +DCM G DE C + NCS R C +C +C C
Sbjct: 82 -GTELCVPMSRLCNGIQDCMDGSDEGAHCRELRANCS--RMGCQH--HCVPTPSGPTCYC 136
Query: 5271 DDGYHLSPYDKKTCLRSPSCPK-ANCSHFCIDRRDVGHQCFCAPGYILSENQKDCR-RND 5098
+ + L D KTC C CS C + D C C GY+L + + C+ +N+
Sbjct: 137 NSSFQLQA-DGKTCKDFDECSVYGTCSQLCTNT-DGSFTCGCVEGYLLQPDNRSCKAKNE 194
Query: 5097 TIEAEILMVYGHRLKLFT--IDGHAKATLLSNLTNGV-ALDYDVKSDLVYWTDVAHDGNK 4927
++ +++ + + + G +T+ T A+D+ ++ V W V +
Sbjct: 195 PVDRPPVLLIANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWVHVGDSAAQ 254
Query: 4926 -----AGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRF 4762
A + + + + + SL ++ +A+DWL N Y+ D D I VC+ G
Sbjct: 255 TQLKCARMPGLKGFVDEHTINISLSLHHVEQMAIDWLTGNFYFVDDIDDRIFVCNRNGD- 313
Query: 4761 NRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNA 4582
+ L L +P+ I LDP VF+TD+G + R +MDG N + L D I +P+
Sbjct: 314 TCVTLLDLELYNPKGIALDPAMGKVFFTDYGQIPKVERCDMDGQN-RTKLVDSKIVFPHG 372
Query: 4581 LAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRG-SVRHIFALAVFEDYVYWSDWHNH 4405
+ +D ++ +Y+ DA+ DYI +Y+G R+ +++G + H++ L VFE+Y+Y ++ N
Sbjct: 373 ITLDLVSRLVYWADAYLDYIEVVDYEGKGRQTIIQGILIEHLYGLTVFENYLYATNSDNA 432
Query: 4404 TIERVHKITGTNR----KVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPC-----SQPA 4252
++ + NR + + + + I H Q + H C +P
Sbjct: 433 NTQQKTSVIRVNRFNSTEYQVVTRVDKGGALHIYHQRRQP----RVRSHACENDQYGKPG 488
Query: 4251 RCDNLCIPANTPDLTTSSDNFTCMCAQGFR--SEGRSC 4144
C ++C+ AN S TC C GF S+G+SC
Sbjct: 489 GCSDICLLAN------SHKARTCRCRSGFSLGSDGKSC 520
Score = 174 bits (440), Expect = 3e-41
Identities = 103/277 (37%), Positives = 134/277 (48%), Gaps = 10/277 (3%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADES-NC---TCNE-NEFR 6409
+DE CS R C P F+C +G CIP C+ +DC + +DES +C TC +F
Sbjct: 925 EDESNATCSARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQFT 984
Query: 6408 CQSGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKC 6229
C +G CI RC++ DC D SDE GC +CS+ C + +CI W C
Sbjct: 985 CNNGRCININWRCDNDNDCGDNSDEAGCS-HSCSSTQ-------FKC-NSGRCIPEHWTC 1035
Query: 6228 DGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCA 6049
DG NDC D SDE + T + P C + +F C C+P W+CDG DC
Sbjct: 1036 DGDNDCGDYSDE----THANCTNQATRPPGGCHS-DEFQCRLDGLCIPLRWRCDGDTDCM 1090
Query: 6048 DGSDEKNCD--AKKC-TSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGG 5878
D SDEK+C+ C + +F C+ S +CI CDG DC D DE CE
Sbjct: 1091 DSSDEKSCEGVTHVCDPNVKFGCKDSARCISKAWVCDGDSDCEDNSDEENCEALACRPPS 1150
Query: 5877 NATFRCTNHR--CIPMAWRCDGTDDCMDNAKSLGSDE 5773
+ C N+ C+P CDG DDC D GSDE
Sbjct: 1151 HP---CANNTSVCLPPDKLCDGKDDCGD-----GSDE 1179
Score = 155 bits (393), Expect = 1e-35
Identities = 110/387 (28%), Positives = 180/387 (46%), Gaps = 15/387 (3%)
Frame = -1
Query: 5259 HLSPYDKKTCLRSP-----SCPKANCSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDT 5095
H+ YD+ L S +CS C+ + C C GY L Q+ C +
Sbjct: 1833 HMKVYDESIQLEHEGTNPCSVNNGDCSQLCLPTSETTRSCMCTAGYSLRSGQQAC---EG 1889
Query: 5094 IEAEILMVYGHRLKLFTIDGHAKATLL---SNLTNGVALDYDVKSDLVYWTDVAHDGNKA 4924
+ + +L ++ +D + K+ L S + V +D+ ++D +YW D+
Sbjct: 1890 VGSFLLYSVHEGIRGIPLDPNDKSDALVPVSGTSLAVGIDFHAENDTIYWVDM------- 1942
Query: 4923 GITSMSNQPNTYRVINSLPTKGI---DGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRI 4753
G++++S + T GI +GIAVDW+ NIY+TD+ D I V + G F +
Sbjct: 1943 GLSTISRAKRDQTWREDVVTNGIGRVEGIAVDWIAGNIYWTDQGFDVIEVARLNGSFRYV 2002
Query: 4752 LLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAV 4573
++ L+ PRAI + P + +FWT+WG I R +DG+ E+V+L + +I WPN ++V
Sbjct: 2003 VI-SQGLDKPRAITVHPEKGYLFWTEWGHYPRIERSRLDGT-ERVVLVNVSISWPNGISV 2060
Query: 4572 DAPAQRLYFGDAHRDYIASCNYD-GSKRRMVLRGSVRHIFALAVFEDYVYWSD--WHNHT 4402
D +LY+ DA D I + + G R +VL + +F+++VFED++YWSD N +
Sbjct: 2061 DYQGGKLYWCDARMDKIERIDLETGENREVVLSSNNMDMFSVSVFEDFIYWSDRTHANGS 2120
Query: 4401 IERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDNLCIPAN 4222
I+R K T+ L + K+ + Q ++ + C LC
Sbjct: 2121 IKRGCKDNATDSVPLRTGIGVQLKDIKVFNRDRQKGTNVCAVAN-----GGCQQLC---- 2171
Query: 4221 TPDLTTSSDNFTCMCAQGFRSE-GRSC 4144
L C CA G +E G SC
Sbjct: 2172 ---LYRGGGQRACACAHGMLAEDGASC 2195
Score = 129 bits (324), Expect = 1e-27
Identities = 97/365 (26%), Positives = 166/365 (44%), Gaps = 13/365 (3%)
Frame = -1
Query: 5199 CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAK-- 5026
CSH C+ + C C L ++ C E + ++Y ++++ +D A
Sbjct: 1550 CSHLCLINYNRTVSCACPHLMKLHKDNTTC-----YEFKKFLLYARQMEIRGVDLDAPYY 1604
Query: 5025 ----ATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKG 4858
+ + ++ N LDYD + VYW+DV K + + + S
Sbjct: 1605 NYIISFTVPDIDNVTVLDYDAREQRVYWSDVRTQAIKRAFINGTG----VETVVSADLPN 1660
Query: 4857 IDGIAVDWLGRNIYYT--DRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVF 4684
G+AVDW+ RN+++T D N I V + G F +++G L P +V+ PL+ ++
Sbjct: 1661 AHGLAVDWVSRNLFWTSYDTNKKQINVARLDGSFKNAVVQG--LEQPHGLVVHPLRGKLY 1718
Query: 4683 WTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYD 4504
WTD +I NMDGSN ++ + + P LA+D P +LY+ + I CN D
Sbjct: 1719 WTD---GDNISMANMDGSNHTLLFSGQ--KGPVGLAIDFPESKLYWISSGNHTINRCNLD 1773
Query: 4503 GSKRRMV--LRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPM 4330
GS+ ++ +R + ALA+ D ++W+D + + +K G+ V++++ M
Sbjct: 1774 GSELEVIDTMRSQLGKATALAIMGDKLWWADQVSEKMGTCNKADGSG-SVVLRNSTTLVM 1832
Query: 4329 GFKIVHPSLQSMGSLKTARHPCS-QPARCDNLCIPANTPDLTTSSDNFTCMCAQGF--RS 4159
K+ S+Q +PCS C LC+P TS +CMC G+ RS
Sbjct: 1833 HMKVYDESIQLE---HEGTNPCSVNNGDCSQLCLP-------TSETTRSCMCTAGYSLRS 1882
Query: 4158 EGRSC 4144
++C
Sbjct: 1883 GQQAC 1887
Score = 128 bits (322), Expect = 2e-27
Identities = 91/341 (26%), Positives = 129/341 (37%)
Frame = -1
Query: 1173 ECLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCS 994
+C NGG C + N+ R P C C +TGD CE C +
Sbjct: 4204 QCFNGGSC-FLNARRQ-PKCRCQPRYTGDKCELDQCWE---------------------- 4239
Query: 993 CEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYC 814
+CHNGG C +P C+C F GP+C V C YC
Sbjct: 4240 ---------------------YCHNGGTCAASPSGMPTCRCPTGFTGPKCTAQV-CAGYC 4277
Query: 813 TNNSKCTITNGTHFECDCKPGFKGLRCEQETKCSECSNEAKCIKKPSGTVICQCPQGLGG 634
+NNS CT+ G +C C PGF G RC+ C N C G+ C+C G
Sbjct: 4278 SNNSTCTVNQGNQPQCRCLPGFLGDRCQYRQCSGFCENFGTCQMAADGSRQCRCTVYFEG 4337
Query: 633 EYCEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCLHDG 454
CE + C Q G C+ + + TC C+ G C + C + C + G
Sbjct: 4338 PRCEVNKCSRCLQ------GACVVNKQTGD---VTCNCTDGRVAPSCLT--CIDHCSNGG 4386
Query: 453 NCTLDEYFEPQCECYQAFIGDRCQYRIHQHAVIFSDDDSGWIKSFXXXXXXXXXXXXXXX 274
+CT++ P+C+C G RC+ + + S G + S
Sbjct: 4387 SCTMNSKMMPECQCPPHMTGPRCEEQ------VVSQQQPGHMASILIPLLLLLLLLLVAG 4440
Query: 273 IFANRSNRFAVFRQFRHNPLQNQGAPVDQFSNPAYLIDEGG 151
+ R + F+H + N GA + NP Y + EGG
Sbjct: 4441 VVFWYKRRVRGAKGFQHQRMTN-GAMNVEIGNPTYKMYEGG 4480
Score = 116 bits (291), Expect = 6e-24
Identities = 113/465 (24%), Positives = 182/465 (38%), Gaps = 18/465 (3%)
Frame = -1
Query: 3153 KEWQVCDGRWDCADGLDESPEMCASRKA-RCFRIGY-CDDKKQCLDVSTALCDGIRDCFD 2980
K W+ CDG DC DG DE+PE+C KA RC + C + C+ +S LC+GI+DC D
Sbjct: 44 KGWR-CDGERDCPDGSDEAPEICPQSKAQRCPPNEHSCLGTELCVPMS-RLCNGIQDCMD 101
Query: 2979 GSDENPIHCKDMCKGKYRC-TNGRCIDVSARXXXXXXXXXXXXXXXXGA----ECHHFGV 2815
GSDE HC+++ R C+ + EC +G
Sbjct: 102 GSDEG-AHCRELRANCSRMGCQHHCVPTPSGPTCYCNSSFQLQADGKTCKDFDECSVYGT 160
Query: 2814 CAQKCWMAFNHTARCHCAPGYARTKNDENEC----EPLSKSAEMFITNGNRLHLMSLENS 2647
C+Q C + + C C GY + D C EP+ + + I N + L +
Sbjct: 161 CSQLCTNT-DGSFTCGCVEGYL-LQPDNRSCKAKNEPVDRPPVLLIANSQNILATYLSGA 218
Query: 2646 QVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEE 2467
QVS + P + +DF Y T VG ++ ++ + GL G E
Sbjct: 219 QVSTITPTSTRQTT----AMDFSY-ANETVCWVHVGDSAAQTQLKCAR-MPGLKGFVDEH 272
Query: 2466 ESTAGL-------ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNS 2308
L + D++ N YF + D I+V + TL+
Sbjct: 273 TINISLSLHHVEQMAIDWLTGNFYFVD----------DIDDRIFVCNRNGDTCVTLLDLE 322
Query: 2307 TGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPT 2128
+A+DP +F+T +P++ ++DG Q LV+ I P
Sbjct: 323 LYNPKGIALDPAMGKVFFTDYGQIPKVERCDMDG-----------QNRTKLVDSKIVFPH 371
Query: 2127 SMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITRQG 1948
+ LD + +YW D IE V ++G+ R+T+ + L + + V Y+Y
Sbjct: 372 GITLDLVSRLVYWADAYLDYIEVVDYEGKGRQTIIQGILIEHLYGLTVFENYLYATNSDN 431
Query: 1947 SIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQK 1813
+ + + N++ +V R+ K HI HQ+
Sbjct: 432 ANTQQKTSVIRVNRFNSTEYQVVTRVD-------KGGALHIYHQR 469
Score = 107 bits (268), Expect = 3e-21
Identities = 194/881 (22%), Positives = 314/881 (35%), Gaps = 68/881 (7%)
Frame = -1
Query: 2820 GVCAQKCWMAFNHTAR-CHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQ 2644
G C+ C +A +H AR C C G++ +D C+ + G + ++
Sbjct: 488 GGCSDICLLANSHKARTCRCRSGFS-LGSDGKSCKKPEHELFLVYGKGRPGIIRGMDMGA 546
Query: 2643 VSVLRPVFNIKMNLIPGGIDF----GYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSW 2476
+ I+ + P +DF G+ F T Y +G R DG+
Sbjct: 547 KVPDEHMIPIENLMNPRALDFHAETGFIYFADTTSYLIGRQKIDGTERETILKDGIHNVE 606
Query: 2475 GEEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTST--RTLIVNSTG 2302
G + D+M +N+Y+T+ + I VA+ + + +TLI
Sbjct: 607 G--------VAVDWMGDNLYWTDDGPKK---------TISVARLEKAAQTRKTLIEGKMT 649
Query: 2301 TINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSM 2122
++ VDP+ ++WT P+ + G+ + + + GS + + + P +
Sbjct: 650 HPRAIVVDPLNGWMYWTDWEEDPK---DSRRGR-LERAWMDGSHRDIFVTSKTVLWPNGL 705
Query: 2121 VLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT-RQGS 1945
LD RLYW+D IET+ +G DR+ V + + + G Y++ R GS
Sbjct: 706 SLDIPAGRLYWVDAFYDRIETILLNGTDRKIVYEGPELNHAFGLCHHGNYLFWTEYRSGS 765
Query: 1944 IHRMHKFTGKTNKYVQKIREVSPRI-QIRVAHPAKHTV-SHITHQKNPCQSDYC---PSN 1780
++R+ + V +R P I +IR+ + V ++ N S C P +
Sbjct: 766 VYRLERGVAGAPPTVTLLRSERPPIFEIRMYDAQQQQVGTNKCRVNNGGCSSLCLATPGS 825
Query: 1779 TVCVPDQDK-----------NGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCGDYF 1633
C +D+ N +P C PG F + +C+Q R K GD
Sbjct: 826 RQCACAEDQVLDTDGVTCLANPSYVPPPQCQPGE-FACANNRCIQERWKCD-----GDND 879
Query: 1632 CYNNAGCSPQ--KTCVCPPGFYGRQCEINECSETCW---NGETCAVQEFGSTTNVVCH-- 1474
C +N+ +P CP + +CE N C W C E +N C
Sbjct: 880 CLDNSDEAPALCHQHTCPSDRF--KCENNRCIPNRWLCDGDNDCGNSE--DESNATCSAR 935
Query: 1473 -CPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHKAD 1297
CP N Q SCA+ C + + C D+ +C R
Sbjct: 936 TCPPN--QFSCASGRCIPI--------SWTCDLDD---------DCGD-------RSDES 969
Query: 1296 AKVCYGHCF-------SGGACDGEGPLNLRC----SCGDGLTGNRCQNCVGHECLNGGFC 1150
A Y CF + G C +N RC CGD C H C + F
Sbjct: 970 ASCAYPTCFPLTQFTCNNGRCIN---INWRCDNDNDCGDNSDEAGC----SHSCSSTQF- 1021
Query: 1149 SYANSNRSLP-HCICP-SGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCSCEQNAA 976
NS R +P H C GD+ +E + CT T+P P C ++
Sbjct: 1022 -KCNSGRCIPEHWTCDGDNDCGDYSDE--------THANCTNQATRP--PGGCHSDEFQC 1070
Query: 975 AHNTDCSPICQKQPNW-CHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSK 799
+ C P+ W C C+D+ C+ + P +V C D SK
Sbjct: 1071 RLDGLCIPL-----RWRCDGDTDCMDSSD-EKSCEGVTHVCDP--NVKFGCKDSARCISK 1122
Query: 798 CTITNGTHFECDCKPGFKGLRCEQ---ETKCSECSNEAKCIKKPSGTVICQCPQGLGGEY 628
+ +G + DC+ CE C+N P +C G
Sbjct: 1123 AWVCDG---DSDCEDNSDEENCEALACRPPSHPCANNTSVCLPPD--KLCDGKDDCGDGS 1177
Query: 627 CEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCS----------SNAC 478
E C Q NGG S C +PG +G++CS ++ C
Sbjct: 1178 DE---GELCDQCSLNNGG-----------CSHNCSVAPG-EGIVCSCPLGMELGSDNHTC 1222
Query: 477 --ENFCLHDGNCTL---DEYFEPQCECYQAFI----GDRCQ 382
+++C C+ F +C CY+ ++ G+ C+
Sbjct: 1223 QIQSYCAKHLKCSQKCDQNKFSVKCSCYEGWVLEPDGESCR 1263
Score = 89.4 bits (220), Expect = 1e-15
Identities = 43/114 (37%), Positives = 62/114 (53%), Gaps = 5/114 (4%)
Frame = -1
Query: 6165 TGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADGSDE-----KNCDAKKCTSF 6001
+G ++ AP++C K QFAC TC+ K W+CDG+ DC DGSDE A++C
Sbjct: 18 SGATMDAPKTCSPK-QFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPN 76
Query: 6000 EFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNATFRCTNHRCIP 5839
E SC ++ C+P+ + C+G +DC DG DE C N + H C+P
Sbjct: 77 EHSCLGTELCVPMSRLCNGIQDCMDGSDE---GAHCRELRANCSRMGCQHHCVP 127
Score = 69.3 bits (168), Expect = 1e-09
Identities = 55/184 (29%), Positives = 75/184 (39%), Gaps = 15/184 (8%)
Frame = -1
Query: 3858 CTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDEL-----NCEITSCKPDFFACFNGTAIS 3694
C+ QF C D+ CI CD E+DC DGSDE + C P+ +C GT +
Sbjct: 28 CSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEHSCL-GTEL- 85
Query: 3693 KCIPKEFYCDGEDDCPEGQDEPDSCFGIGE------CTHEQFQCTSGKCIPKRRQCDGTL 3532
C+P C+G DC +G DE C + C H SG C+ +
Sbjct: 86 -CVPMSRLCNGIQDCMDGSDEGAHCRELRANCSRMGCQHHCVPTPSGPTC----YCNSSF 140
Query: 3531 DCRDGSDEKGCK--KECAI--VCDNSCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKE 3364
+ +D K CK EC++ C C + DG C CV LL+ +
Sbjct: 141 QLQ--ADGKTCKDFDECSVYGTCSQLCTNT----DGSFTC---------GCVEGYLLQPD 185
Query: 3363 NRKC 3352
NR C
Sbjct: 186 NRSC 189
Score = 63.9 bits (154), Expect = 5e-08
Identities = 75/303 (24%), Positives = 118/303 (38%), Gaps = 8/303 (2%)
Frame = -1
Query: 2820 GVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQV 2641
G C+Q C T C C GY+ ++ + CE + + G R + N +
Sbjct: 1856 GDCSQLCLPTSETTRSCMCTAGYS-LRSGQQACEGVGSFLLYSVHEGIRGIPLD-PNDKS 1913
Query: 2640 SVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEES 2461
L PV + + GIDF + +Y V +G S + R+K+ +W E+
Sbjct: 1914 DALVPVSGTSLAV---GIDFHAE---NDTIYWVDMGLSTIS-RAKRDQ-----TWREDVV 1961
Query: 2460 TAGL-----ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTI 2296
T G+ I D++ N+Y+T+ FD I VA+ + +I
Sbjct: 1962 TNGIGRVEGIAVDWIAGNIYWTDQG-------FDV---IEVARLNGSFRYVVISQGLDKP 2011
Query: 2295 NSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVL 2116
++ V P K +FWT PRI + LDG LV +I P + +
Sbjct: 2012 RAITVHPEKGYLFWTEWGHYPRIERSRLDG-----------TERVVLVNVSISWPNGISV 2060
Query: 2115 DFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITR---QGS 1945
D+ +LYW D IE + + + R V ++ V +IY R GS
Sbjct: 2061 DYQGGKLYWCDARMDKIERIDLETGENREVVLSSNNMDMFSVSVFEDFIYWSDRTHANGS 2120
Query: 1944 IHR 1936
I R
Sbjct: 2121 IKR 2123
Score = 62.0 bits (149), Expect = 2e-07
Identities = 44/157 (28%), Positives = 56/157 (35%), Gaps = 20/157 (12%)
Frame = -1
Query: 6270 CATTSQCIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAK-------TQFA 6112
C CI W+CDG DC DGSDE AP C + +
Sbjct: 35 CRDQITCISKGWRCDGERDCPDGSDE---------------APEICPQSKAQRCPPNEHS 79
Query: 6111 CLATRTCMPKHWQCDGQPDCADGSDE--------KNCDAKKCTSFEFSCESSKKCI---P 5965
CL T C+P C+G DC DGSDE NC C S C
Sbjct: 80 CLGTELCVPMSRLCNGIQDCMDGSDEGAHCRELRANCSRMGCQHHCVPTPSGPTCYCNSS 139
Query: 5964 LEQKCDGR--RDCPDGEDEHQCETECDSKGGNATFRC 5860
+ + DG+ +D + C C + G+ T C
Sbjct: 140 FQLQADGKTCKDFDECSVYGTCSQLCTNTDGSFTCGC 176
Score = 61.6 bits (148), Expect = 2e-07
Identities = 63/255 (24%), Positives = 88/255 (33%), Gaps = 20/255 (7%)
Frame = -1
Query: 5913 HQCETECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVP 5734
HQ C +GG R + + C N+ DE +CA G
Sbjct: 2498 HQGHVNCSCRGG---------RILQEDFTCRAV-----NSSCRAQDEFECANGE------ 2537
Query: 5733 SRCADETCVVACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLC 5554
C ++ CDG+ C D DEK R+CK C++G+C+ + C
Sbjct: 2538 -----------CISFSLTCDGVSHCKDKSDEKPSYCNSRRCKKTFRQCNNGRCVSNMLWC 2586
Query: 5553 DASVDCVDGSDEW---VEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMS 5383
+ DC DGSDE C + E C G C+ C+ DC
Sbjct: 2587 NGVDDCGDGSDEIPCNKTACGVGE---FRCRDG----------SCIGNSSRCNQFVDCED 2633
Query: 5382 GIDEQCDNPQGNCSSTRNS--------------CDQTWNCQRHAGFESCSCDDGYHLSPY 5245
DE NCS+T S C++T C S CD Y
Sbjct: 2634 ASDEM------NCSATDCSSYFRLGVKGVLFQPCERTSLCYA----PSWVCDGANDCGDY 2683
Query: 5244 -DKKTC--LRSPSCP 5209
D++ C ++ P CP
Sbjct: 2684 SDERDCPGVKRPRCP 2698
Score = 57.4 bits (137), Expect = 5e-06
Identities = 48/184 (26%), Positives = 67/184 (36%), Gaps = 13/184 (7%)
Frame = -1
Query: 4008 PFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFE---CTEAQFK 3838
P C QF C C+ CDG +DC G DE P C + C +
Sbjct: 25 PKTCSPKQFAC-----RDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEHS 79
Query: 3837 CGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCKPDFFACFNGTAISKCIP----KEFY 3670
C + C+P++ +C+ +DC DGSD E C+ C C+P Y
Sbjct: 80 CLGTELCVPMSRLCNGIQDCMDGSD----EGAHCRELRANCSRMGCQHHCVPTPSGPTCY 135
Query: 3669 CDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQCDG--TLDCRDG----SDE 3508
C+ Q + +C EC+ G C DG T C +G D
Sbjct: 136 CNSSFQL---QADGKTCKDFDECS------VYGTCSQLCTNTDGSFTCGCVEGYLLQPDN 186
Query: 3507 KGCK 3496
+ CK
Sbjct: 187 RSCK 190
Score = 52.8 bits (125), Expect = 1e-04
Identities = 78/393 (19%), Positives = 140/393 (34%), Gaps = 14/393 (3%)
Frame = -1
Query: 2820 GVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQV 2641
G C+ C + +N T C C P + D C K L+ +E V
Sbjct: 1548 GPCSHLCLINYNRTVSCAC-PHLMKLHKDNTTCYEFKKFL---------LYARQMEIRGV 1597
Query: 2640 SVLRPVFNIKMNLIPGGID----FGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWG 2473
+ P +N ++ ID YD + ++ D+R++ I G
Sbjct: 1598 DLDAPYYNYIISFTVPDIDNVTVLDYDAREQRVYWS--------DVRTQAIKRAFINGTG 1649
Query: 2472 EEE------STAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVN 2311
E A + D++ N+++T S + N+ +Q N+ D S + +V
Sbjct: 1650 VETVVSADLPNAHGLAVDWVSRNLFWT-SYDTNK-----KQINV---ARLDGSFKNAVVQ 1700
Query: 2310 STGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEP 2131
+ L V P++ ++WT I AN+DG + L+ P
Sbjct: 1701 GLEQPHGLVVHPLRGKLYWTDG---DNISMANMDGS------------NHTLLFSGQKGP 1745
Query: 2130 TSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTV--RKFELGDTPVTMDVLGGYIYLIT 1957
+ +DF +LYWI TI + DG + + + +LG + ++G ++
Sbjct: 1746 VGLAIDFPESKLYWISSGNHTINRCNLDGSELEVIDTMRSQLGKA-TALAIMGDKLWW-- 1802
Query: 1956 RQGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVS-HITHQ-KNPCQSDYCPS 1783
++ + G NK V V H + S + H+ NPC +
Sbjct: 1803 ----ADQVSEKMGTCNKADGSGSVVLRNSTTLVMHMKVYDESIQLEHEGTNPCSVNNGDC 1858
Query: 1782 NTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKC 1684
+ +C+P + C+C G + C
Sbjct: 1859 SQLCLPTSETT----RSCMCTAGYSLRSGQQAC 1887
Score = 52.0 bits (123), Expect = 2e-04
Identities = 49/173 (28%), Positives = 62/173 (35%), Gaps = 6/173 (3%)
Frame = -1
Query: 6432 TCNENEFRCQSG-ACIPSKARCNHMQDCNDASDEIG--CPFRNCSAL--NEFGMTGLINC 6268
TC+ +F C+ CI RC+ +DC D SDE CP NE +C
Sbjct: 27 TCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEH------SC 80
Query: 6267 ATTSQCIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCM 6088
T C+ S C+G DC DGSDE E A + Q C+ T
Sbjct: 81 LGTELCVPMSRLCNGIQDCMDGSDEGAHCRELRANCSRMGC--------QHHCVPT---- 128
Query: 6087 PKHWQCDGQPDC-ADGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDC 5932
P C + S + D K C F+ C C L DG C
Sbjct: 129 ------PSGPTCYCNSSFQLQADGKTCKDFD-ECSVYGTCSQLCTNTDGSFTC 174
Score = 40.4 bits (93), Expect = 0.59
Identities = 34/130 (26%), Positives = 49/130 (37%), Gaps = 10/130 (7%)
Frame = -1
Query: 6570 DEDTKYC---STRVCRPGYFNC-GNGLCIPEQKVCNRINDCANFADESNCTCNENEFRCQ 6403
DE + C + C P +C G LC+P ++CN I DC + +DE C E C
Sbjct: 59 DEAPEICPQSKAQRCPPNEHSCLGTELCVPMSRLCNGIQDCMDGSDE-GAHCRELRANCS 117
Query: 6402 SGAC------IPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHP 6241
C PS C CN +S ++ + C +E C+ C
Sbjct: 118 RMGCQHHCVPTPSGPTCY----CN-SSFQLQADGKTCKDFDE--------CSVYGTCSQL 164
Query: 6240 SWKCDGTNDC 6211
DG+ C
Sbjct: 165 CTNTDGSFTC 174
>gi|15825096|gb|AAL09567.1| lipoprotein receptor-related protein [Mus
musculus]
Length = 4545
Score = 860 bits (2222), Expect = 0.0
Identities = 623/2001 (31%), Positives = 879/2001 (43%), Gaps = 161/2001 (8%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCT---CNENEFRCQS 6400
DE YC++R C+ + C NG C+ CN ++DC + +DE C C EFRC+
Sbjct: 2556 DEKPSYCNSRRCKKTFRQCNNGRCVSNMLWCNGVDDCGDGSDEIPCNKTACGVGEFRCRD 2615
Query: 6399 GACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLI--NCATTSQCIHPSWKCD 6226
G+CI + +RCN DC DASDE+ C +CS+ G+ G++ C TS C PSW CD
Sbjct: 2616 GSCIGNSSRCNQFVDCEDASDEMNCSTTDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCD 2675
Query: 6225 GTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCAD 6046
G NDC D SDE+DC V PR FAC + R C+P W CD + DC +
Sbjct: 2676 GANDCGDYSDERDC--------PGVKRPRC--PLNYFACPSGR-CIPMSWTCDKEDDCEN 2724
Query: 6045 GSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKG-GNAT 5869
G DE +C+ K C+ +F C++ + CI + CDG DC DG DE C+ K G ++
Sbjct: 2725 GEDETHCN-KFCSEAQFECQNHR-CISKQWLCDGSDDCGDGSDE---AAHCEGKTCGPSS 2779
Query: 5868 FRCTN-HRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACEL 5692
F C H C+P W CDG DC D A S C T C + C+
Sbjct: 2780 FSCPGTHVCVPERWLCDGDKDCTDGADE--SVTAGCLYNSTCDDREFMCQNRLCIPK--- 2834
Query: 5691 TAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRL-CDASVDCVDGSDEW 5515
+CD +DC+DG DE C PNE+ C +G+C+ S + CD DC D SDE
Sbjct: 2835 -HFVCDHDRDCADGSDESPECEYPT-CGPNEFRCANGRCLSSRQWECDGENDCHDHSDEA 2892
Query: 5514 VEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSST 5335
+ + P + C + L ++G C+ E LC+G+ DC G DE+ + S
Sbjct: 2893 PKNPHCTSPEHK-CNASSQFLCSSGR--CVAEALLCNGQDDCGDGSDERGCHVNECLSRK 2949
Query: 5334 RNSCDQTWNCQR-HAGFESCSCDDGYHLSPYDKKTCLRSPSCPKA-NCSHFCIDRRDVGH 5161
+ C Q +C+ GF+ C C G+ L D +TC C CS CI+ +
Sbjct: 2950 LSGCSQ--DCEDLKIGFK-CRCRPGFRLKD-DGRTCADLDECSTTFPCSQLCINTHG-SY 3004
Query: 5160 QCFCAPGYI-LSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLTNGVALD 4984
+C C GY + C+ E ++ + L+ +DG L L N VALD
Sbjct: 3005 KCLCVEGYAPRGGDPHSCKAVTDEEPFLIFANRYYLRKLNLDGSNYTLLKQGLNNAVALD 3064
Query: 4983 YDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDR 4804
+D + ++YWTDV G+ I M + +V++ DG+AVDW+G N+Y+ D+
Sbjct: 3065 FDYREQMIYWTDVTTQGSM--IRRMHLNGSNVQVLHRTGLSNPDGLAVDWVGGNLYWCDK 3122
Query: 4803 NHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNE 4624
D I V + G + +L+ + L +PRA+V+D ++WTDWG + IGR+ MDGS
Sbjct: 3123 GRDTIEVSKLNGAYRTVLVS-SGLREPRALVVDVQNGYLYWTDWGDHSLIGRIGMDGSGR 3181
Query: 4623 QVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAV 4444
+I+ D I WPN L VD +R+Y+ DA DYI + DGS R +VL + HIFAL +
Sbjct: 3182 SIIV-DTKITWPNGLTVDYVTERIYWADAREDYIEFASLDGSNRHVVLSQDIPHIFALTL 3240
Query: 4443 FEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPC 4264
FEDYVYW+DW +I R HK TG N+ +LI +RPM + H Q HPC
Sbjct: 3241 FEDYVYWTDWETKSINRAHKTTGANKTLLISTL-HRPMDLHVFHALRQP----DVPNHPC 3295
Query: 4263 S-QPARCDNLCIPANTPDLTTSSDNFTCMCAQGFR--SEGRSCVSECKPNDFVCTKTYKC 4093
C NLC L + C C F +GR+CVS C + FVC K KC
Sbjct: 3296 KVNNGGCSNLC-------LLSPGGGHKCACPTNFYLGGDGRTCVSNCTASQFVC-KNDKC 3347
Query: 4092 ISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGV 3913
I WW+ CP F C GQF C +T C + +CDG
Sbjct: 3348 IPFWWKCDTEDDCGDHSDE----PPDCPEFKCRPGQFQC------STGICTNPAFICDGD 3397
Query: 3912 KDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCK 3733
DC DE A C+ C +QFKC + +CIP C+ + +C DG DE +C +C
Sbjct: 3398 NDCQDNSDE--ANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTCA 3455
Query: 3732 PDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCT-SGKCIPK 3556
P+ F C + +CIP+ + CD ++DC +G DEP +C + C ++F+C SG+CIP
Sbjct: 3456 PNQFQC---SITKRCIPRVWVCDRDNDCVDGSDEPANCTQM-TCGVDEFRCKDSGRCIPA 3511
Query: 3555 RRQCDGTLDCRDGSDEKGCKKEC-AIVCD--------NSCVHADDLCDGKKKCNDGSDED 3403
R +CDG DC DGSDE K+EC C+ N CV CD C D SDE
Sbjct: 3512 RWKCDGEDDCGDGSDEP--KEECDERTCEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDE- 3568
Query: 3402 EEACVIKQLLEKE----NRKC--GGFACDGIVDCEDGSDEKGCP---DLECHLASNKSLI 3250
E+C + E E N +C G + CDG DC DGSDEK C D++ + I
Sbjct: 3569 -ESCTPRPCSESEFSCANGRCIAGRWKCDGDHDCADGSDEKDCTPRCDMDQFQCKSGHCI 3627
Query: 3249 -----CDGTIDCSSGKDENNCHNNGES---NFFQCSMQTIKE--WQVCDGRWDCADGLDE 3100
CD DC G DE C + + FQC+ K W+ CDG DC D DE
Sbjct: 3628 PLRWRCDADADCMDGSDEEACGTGVRTCPLDEFQCNNTLCKPLAWK-CDGEDDCGDNSDE 3686
Query: 3099 SPEMCA------SRKARCFR------IG--------------------------YCDDKK 3034
+PE CA +R RC IG +C DKK
Sbjct: 3687 NPEECARFICPPNRPFRCKNDRVCLWIGRQCDGVDNCGDGTDEEDCEPPTAQNPHCKDKK 3746
Query: 3033 Q-------CLDVSTALCDGIRDCFDGSDENPIHCK----------DMCKGKYRCTNGRCI 2905
+ CL S+ C+ DC DGSDE MC + RC
Sbjct: 3747 EFLCRNQRCLS-SSLRCNMFDDCGDGSDEEDCSIDPKLTSCATNASMCGDEARCVRTEKA 3805
Query: 2904 DVSARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTAR---CHCAPGYARTKND 2734
A EC FG C+Q C N+T C CA + +T
Sbjct: 3806 AYCACRSGFHTVPGQPGCQDIN-ECLRFGTCSQLC----NNTKGGHLCSCARNFMKT--- 3857
Query: 2733 ENECEPLSKSAE-MFITNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRT- 2560
N C+ + ++I + N + + S F ++ +D R
Sbjct: 3858 HNTCKAEGSEYQVLYIADDNEIRSL-FPGHPHSAYEQTFQGDESVRIDAMDVHVKAGRVY 3916
Query: 2559 -TLMYTVGIGNSRVDIRSKKWSDGL----IGSWGEEESTAGL-----ITYDFMHNNVYFT 2410
T +T I + + + I + +GL I D++ NVY+T
Sbjct: 3917 WTNWHTGTISYRSLPPAAPPTTSNRHRRQIDRGVTHLNISGLKMPRGIAIDWVAGNVYWT 3976
Query: 2409 ESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPR 2230
+S I VA+ K + +TLI +++ VDP++ ++W+ P+
Sbjct: 3977 DSGRDV----------IEVAQMKGENRKTLISGMIDEPHAIVVDPLRGTMYWSDWGNHPK 4026
Query: 2229 ILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSF 2050
I +A +DG + LV+ NI PT + +D+ NERLYW D I ++
Sbjct: 4027 IETAAMDGTL-----------RETLVQDNIQWPTGLAVDYHNERLYWADAKLSVIGSIRL 4075
Query: 2049 DGRDRRTVRKFELG-DTPVTMDVLGGYIYLITR-QGSIHRMHKFTGKTNKYVQKIREVSP 1876
+G D + G P ++DV YIY +T + ++HKF SP
Sbjct: 4076 NGTDPIVAADSKRGLSHPFSIDVFEDYIYGVTYINNRVFKIHKFGH------------SP 4123
Query: 1875 RIQIR--VAHPAKHTVSHITHQK---NPCQSDYCPSNTVCVPDQDKNGILIPKCLCGPGR 1711
I + ++H + + H Q NPC C + P P C C G+
Sbjct: 4124 LINLTGGLSHASDVVLYHQHKQPEVTNPCDRKKCEWLCLLSPSG-------PVCTCPNGK 4176
Query: 1710 FFEVSTKKCMQLREKDQEASQCGDYF--CYNNAGC----SPQKTCVCPPGFYGRQCEINE 1549
+ T + +A + G C+N C Q C C P + G +CE+++
Sbjct: 4177 RLDNGTCVPVPSPTPPPDAPRPGTCTLQCFNGGSCFLNARRQPKCRCQPRYTGDKCELDQ 4236
Query: 1548 CSETCWNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEP 1369
C E C NG TCA G T C CP+ +T C VC G C +C ++P
Sbjct: 4237 CWEYCHNGGTCAASPSGMPT---CRCPTGFTGPKCTAQVCAGYCSNNSTCTV--NQGNQP 4291
Query: 1368 HCRSYSFCECDKGWTGPHCRHKADAKVCYGHCFSGGAC----DG----------EGPL-- 1237
CR C G+ G C+++ C G C + G C DG EGP
Sbjct: 4292 QCR------CLPGFLGDRCQYRQ----CSGFCENFGTCQMAADGSRQCRCTVYFEGPRCE 4341
Query: 1236 -------------------NLRCSCGDGLTGNRCQNCVGHECLNGGFCSYANSNRSLPHC 1114
++ C+C DG C C+ H C NGG C+ +++ +P C
Sbjct: 4342 VNKCSRCLQGACVVNKQTGDVTCNCTDGRVAPSCLTCIDH-CSNGGSCTM--NSKMMPEC 4398
Query: 1113 ICPSGFTGDHCEEYLCKDACP 1051
CP TG CEE + P
Sbjct: 4399 QCPPHMTGPRCEEQVVSQQQP 4419
Score = 375 bits (962), Expect = e-101
Identities = 312/1088 (28%), Positives = 441/1088 (39%), Gaps = 83/1088 (7%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGN-GLCIPEQKVCNRINDCANFADESNC---TCNENEFRC 6406
D+ D C VC P F C N CIP CN ++C + DE +C TC N+F+C
Sbjct: 3402 DNSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTCAPNQFQC 3461
Query: 6405 Q-SGACIPSKARCNHMQDCNDASDE-IGCPFRNCSALNEFGMTGLINCATTSQCIHPSWK 6232
+ CIP C+ DC D SDE C C ++EF C + +CI WK
Sbjct: 3462 SITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTC-GVDEF------RCKDSGRCIPARWK 3514
Query: 6231 CDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKT----QFACLATRTCMPKHWQCDG 6064
CDG +DC DGSDE CD +T QF C R C+P WQCD
Sbjct: 3515 CDGEDDCGDGSDE---------------PKEECDERTCEPYQFRCKNNR-CVPGRWQCDY 3558
Query: 6063 QPDCADGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSK 5884
DC D SDE++C + C+ EFSC ++ +CI KCDG DC DG DE C CD
Sbjct: 3559 DNDCGDNSDEESCTPRPCSESEFSC-ANGRCIAGRWKCDGDHDCADGSDEKDCTPRCDMD 3617
Query: 5883 GGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVV 5704
F+C + CIP+ WRCD DCMD GSDE C G + + + T
Sbjct: 3618 ----QFQCKSGHCIPLRWRCDADADCMD-----GSDEEACGTGVRTCPLDEFQCNNT--- 3665
Query: 5703 ACELTAVLCDGIQDCSDGFDE--KNCASLDRQCKPNE-WMCDSGQ-CIDSGRLCDASVDC 5536
C+ A CDG DC D DE + CA C PN + C + + C+ GR CD +C
Sbjct: 3666 LCKPLAWKCDGEDDCGDNSDENPEECARF--ICPPNRPFRCKNDRVCLWIGRQCDGVDNC 3723
Query: 5535 VDGSDEWVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQ---C 5365
DG+DE E C C L N CL C+ DC G DE+
Sbjct: 3724 GDGTDE--EDCEPPTAQNPHCKDKKEFLCRNQR--CLSSSLRCNMFDDCGDGSDEEDCSI 3779
Query: 5364 DNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSP-----YDKKTCLRSPSCPKAN 5200
D +C++ + C C R C+C G+H P D CLR
Sbjct: 3780 DPKLTSCATNASMCGDEARCVRTEKAAYCACRSGFHTVPGQPGCQDINECLRF-----GT 3834
Query: 5199 CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKAT 5020
CS C + + GH C CA ++ + N C+ + E ++L + GH +
Sbjct: 3835 CSQLCNNTKG-GHLCSCARNFMKTHN--TCKAEGS-EYQVLYIADDNEIRSLFPGHPHSA 3890
Query: 5019 LLSNLTNGV-----ALDYDVKSDLVYWTDVAHDGN---------KAGITSMSNQPNTYRV 4882
A+D VK+ VYWT+ H G TS ++ R
Sbjct: 3891 YEQTFQGDESVRIDAMDVHVKAGRVYWTN-WHTGTISYRSLPPAAPPTTSNRHRRQIDRG 3949
Query: 4881 INSLPTKGID---GIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIV 4711
+ L G+ GIA+DW+ N+Y+TD D I V M+G + L+ G +++P AIV
Sbjct: 3950 VTHLNISGLKMPRGIAIDWVAGNVYWTDSGRDVIEVAQMKGENRKTLISGM-IDEPHAIV 4008
Query: 4710 LDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHR 4531
+DPL+ ++W+DWG I MDG+ + ++QD I+WP LAVD +RLY+ DA
Sbjct: 4009 VDPLRGTMYWSDWGNHPKIETAAMDGTLRETLVQD-NIQWPTGLAVDYHNERLYWADAKL 4067
Query: 4530 DYIASCNYDGSKRRMVL--RGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVL 4357
I S +G+ + + + H F++ VFEDY+Y + N+ + ++HK G + +
Sbjct: 4068 SVIGSIRLNGTDPIVAADSKRGLSHPFSIDVFEDYIYGVTYINNRVFKIHKF-GHSPLIN 4126
Query: 4356 IQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDNLCIPANTPDLTTSSDNFTCMC 4177
+ + H Q +PC + +C+ LC+ S C C
Sbjct: 4127 LTGGLSHASDVVLYHQHKQ-----PEVTNPCDR-KKCEWLCL--------LSPSGPVCTC 4172
Query: 4176 AQGFRSEGRSCV---SECKPND--------FVCTKTYKCISSWWRXXXXXXXXXXXXXGY 4030
G R + +CV S P D C C + R
Sbjct: 4173 PNGKRLDNGTCVPVPSPTPPPDAPRPGTCTLQCFNGGSCFLNARRQPKCRCQPRYTGDKC 4232
Query: 4029 FVE---------GVCPPFPCIAGQFVC----GRTAQNATAQCLYASKLCDGVKDCSGGDD 3889
++ G C P +G C G T TAQ + C C+
Sbjct: 4233 ELDQCWEYCHNGGTCAASP--SGMPTCRCPTGFTGPKCTAQ--VCAGYCSNNSTCTVNQG 4288
Query: 3888 EEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCD---DGSDEL---------NCEI 3745
+P +C GD+ + + C+ C DGS + CE+
Sbjct: 4289 NQP------QCRCLPGFLGDRCQYRQCSGFCENFGTCQMAADGSRQCRCTVYFEGPRCEV 4342
Query: 3744 TSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEP------DSCFGIGECTHEQFQ 3583
C C G C+ + D +C +G+ P D C G CT
Sbjct: 4343 NKCS----RCLQGA----CVVNKQTGDVTCNCTDGRVAPSCLTCIDHCSNGGSCTMNSKM 4394
Query: 3582 CTSGKCIP 3559
+C P
Sbjct: 4395 MPECQCPP 4402
Score = 369 bits (946), Expect = e-100
Identities = 259/818 (31%), Positives = 354/818 (42%), Gaps = 38/818 (4%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCI--PEQKVCNRINDCANFADESNCT----------C 6427
D + T CR C + LC+ P + C D D C C
Sbjct: 797 DAQQQQVGTNKCRVNNGGCSS-LCLATPGSRQCACAEDQVLDTDGVTCLANPSYVPPPQC 855
Query: 6426 NENEFRCQSGACIPSKARCNHMQDCNDASDEIG--CPFRNCSALNEFGMTGLINCATTSQ 6253
EF C + CI + +C+ DC D SDE C C + C ++
Sbjct: 856 QPGEFACANNRCIQERWKCDGDNDCLDNSDEAPALCHQHTCPS-------DRFKCEN-NR 907
Query: 6252 CIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKT----QFACLATRTCMP 6085
CI W CDG NDC + DE + +C A+T QF+C + R C+P
Sbjct: 908 CIPNRWLCDGDNDCGNSEDESNA---------------TCSARTCPPNQFSCASGR-CIP 951
Query: 6084 KHWQCDGQPDCADGSDEK-NCDAKKCTSF-EFSCESSKKCIPLEQKCDGRRDCPDGEDEH 5911
W CD DC D SDE +C C +F+C + + CI + +CD DC D DE
Sbjct: 952 ISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNGR-CININWRCDNDNDCGDNSDEA 1010
Query: 5910 QCETECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPS 5731
C C S F+C + RCIP W CDG +DC D SDE + P
Sbjct: 1011 GCSHSCSS----TQFKCNSGRCIPEHWTCDGDNDCGDY-----SDETHANCTNQATRPPG 1061
Query: 5730 RCADETCVVACELTAVL------CDGIQDCSDGFDEKNCASLDRQCKPN-EWMC-DSGQC 5575
C + C L + CDG DC D DEK+C + C PN ++ C DS +C
Sbjct: 1062 GCHSDE--FQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPNVKFGCKDSARC 1119
Query: 5574 IDSGRLCDASVDCVDGSDEWVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRR 5395
I +CD DC D SDE PP C N T CL +LCDG+
Sbjct: 1120 ISKAWVCDGDSDCEDNSDEENCEALACRPPSHPC--------ANNTSVCLPPDKLCDGKD 1171
Query: 5394 DCMSGIDEQ--CDNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRS 5221
DC G DE CD CS C + G CSC G L D TC
Sbjct: 1172 DCGDGSDEGELCDQ----CSLNNGGCSHNCSVAPGEGIV-CSCPLGMELGS-DNHTCQIQ 1225
Query: 5220 PSCPK-ANCSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFT 5044
C K CS C D+ +C C G++L + + CR D + I+ H ++
Sbjct: 1226 SYCAKHLKCSQKC-DQNKFSVKCSCYEGWVLEPDGESCRSLDPFKPFIIFSNRHEIRRID 1284
Query: 5043 IDGHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPT 4864
+ + L+ L N +ALD+ + +YWTDV D G + ++ V+
Sbjct: 1285 LHKGDYSVLVPGLRNTIALDFHLSQSALYWTDVVEDKIYRGKLLDNGALTSFEVVIQYGL 1344
Query: 4863 KGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVF 4684
+G+AVDW+ NIY+ + N D I V + G LL G + PRAI LDP ++F
Sbjct: 1345 ATPEGLAVDWIAGNIYWVESNLDQIEVAKLDGTLRTTLLAG-DIEHPRAIALDPRDGILF 1403
Query: 4683 WTDWGAS-AHIGRMNMDGSNEQVILQDR-TIRWPNALAVDAPAQRLYFGDAHRDYIASCN 4510
WTDW AS I +M G+ + I ++ + WPN L VD +R+ + DA D I S
Sbjct: 1404 WTDWDASLPRIEAASMSGAGRRTIHRETGSGGWPNGLTVDYLEKRILWIDARSDAIYSAR 1463
Query: 4509 YDGSKRRMVLRGS--VRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYR 4336
YDGS VLRG + H FA+ ++ VYW+DW +T+ + +K TG N V +Q +
Sbjct: 1464 YDGSGHMEVLRGHEFLSHPFAVTLYGGEVYWTDWRTNTLAKANKWTGHNVTV-VQRTNTQ 1522
Query: 4335 PMGFKIVHPSLQSMGSLKTARHPCSQ---PARCDNLCI 4231
P ++ HPS Q M A +PC C +LC+
Sbjct: 1523 PFDLQVYHPSRQPM-----APNPCEANGGRGPCSHLCL 1555
Score = 367 bits (942), Expect = 2e-99
Identities = 456/1851 (24%), Positives = 691/1851 (36%), Gaps = 225/1851 (12%)
Frame = -1
Query: 5214 CPKAN--CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTI 5041
C AN C C+ R C CA G +L+E+ CR E ++Y R L +I
Sbjct: 2160 CAVANGGCQQLCLYRGGGQRACACAHG-MLAEDGASCR-----EYAGYLLYSERTILKSI 2213
Query: 5040 DGHAKATLLS---------NLTNGVALDYDVKS-------DLVYWTDVAHDGNKAGITSM 4909
+ L + ++ N +AL +D ++ + ++++D+ H GN I
Sbjct: 2214 HLSDERNLNAPVQPFEDPEHMKNVIALAFDYRAGTSPGTPNRIFFSDI-HFGNIQQINDD 2272
Query: 4908 SNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIA---VCDMR-GRFNR---IL 4750
+ T ++ ++ + ++G+A +Y+T I V R G F R I
Sbjct: 2273 GSGRTT--IVENVGS--VEGLAYHRGWDTLYWTSYTTSTITRHTVDQTRPGAFERETVIT 2328
Query: 4749 LKGTPLNDPRAIVLDPLQALVFWTDWGA-SAHIGRMNMDGSNEQVILQDRTIRWPNALAV 4573
+ G + PRA VLD Q L+FWT+W I R + G+N +++ + IR PN LA+
Sbjct: 2329 MSGD--DHPRAFVLDECQNLMFWTNWNELHPSIMRAALSGANVLTLIE-KDIRTPNGLAI 2385
Query: 4572 DAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIER 4393
D A++LYF DA D I C YDGS R ++L+ H F LAV+ ++++W+DW ++R
Sbjct: 2386 DHRAEKLYFSDATLDKIERCEYDGSHRYVILKSEPVHPFGLAVYGEHIFWTDWVRRAVQR 2445
Query: 4392 VHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCS-QPARCDNLCIPANTP 4216
+K G++ K+L D +PMG V S PC C +LC
Sbjct: 2446 ANKYVGSDMKLLRVDIPQQPMGIIAVANDTNSC-----ELSPCRINNGGCQDLC------ 2494
Query: 4215 DLTTSSDNFTCMCAQG-FRSEGRSCV---SECKPNDFVCTKTYKCISSWWRXXXXXXXXX 4048
L T + C C G E +C S C+ D +CIS
Sbjct: 2495 -LLTHQGHVNCSCRGGRILQEDFTCRAVNSSCRAQDEFECANGECIS----------FSL 2543
Query: 4047 XXXXGYFVEGVCPPFPCIAGQFVCGRTAQNAT-AQCLYASKLCDGVKDCSGGDDEEPAFC 3871
+ P C +T + +C+ C+GV DC G DE P C
Sbjct: 2544 TCDGVSHCKDKSDEKPSYCNSRRCKKTFRQCNNGRCVSNMLWCNGVDDCGDGSDEIP--C 2601
Query: 3870 ENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCKPDFFACFNGTAI-- 3697
C +F+C D CI +S C++ DC+D SDE+NC T C F G
Sbjct: 2602 NKTACGVGEFRCRDGS-CIGNSSRCNQFVDCEDASDEMNCSTTDCSSYFRLGVKGVLFQP 2660
Query: 3696 ----SKCIPKEFYCDGEDDCPEGQDEPDSCFGIGE--CTHEQFQCTSGKCIPKRRQCDGT 3535
S C + CDG +DC + DE D C G+ C F C SG+CIP CD
Sbjct: 2661 CERTSLCYAPSWVCDGANDCGDYSDERD-CPGVKRPRCPLNYFACPSGRCIPMSWTCDKE 2719
Query: 3534 LDCRDGSDEKGCKKECA---IVCDNS-CVHADDLCDGKKKCNDGSDEDEEACVIKQLLEK 3367
DC +G DE C K C+ C N C+ LCDG C DGSDE
Sbjct: 2720 DDCENGEDETHCNKFCSEAQFECQNHRCISKQWLCDGSDDCGDGSDEAAHC--------- 2770
Query: 3366 ENRKCGG---------------FACDGIVDCEDGSDEK---------GCPDLEC----HL 3271
E + CG + CDG DC DG+DE C D E L
Sbjct: 2771 EGKTCGPSSFSCPGTHVCVPERWLCDGDKDCTDGADESVTAGCLYNSTCDDREFMCQNRL 2830
Query: 3270 ASNKSLICDGTIDCSSGKDEN-NC-HNNGESNFFQCS---MQTIKEWQVCDGRWDCADGL 3106
K +CD DC+ G DE+ C + N F+C+ + ++W+ CDG DC D
Sbjct: 2831 CIPKHFVCDHDRDCADGSDESPECEYPTCGPNEFRCANGRCLSSRQWE-CDGENDCHDHS 2889
Query: 3105 DESPEM--CASRKARCFRIG-YCDDKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKG 2935
DE+P+ C S + +C + +C+ LC+G DC DGSDE H +
Sbjct: 2890 DEAPKNPHCTSPEHKCNASSQFLCSSGRCV-AEALLCNGQDDCGDGSDERGCHVNECLSR 2948
Query: 2934 KYRCTNGRCIDVS----ARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCH 2767
K + C D+ R EC C+Q C + + + +C
Sbjct: 2949 KLSGCSQDCEDLKIGFKCRCRPGFRLKDDGRTCADLDECSTTFPCSQLC-INTHGSYKCL 3007
Query: 2766 CAPGYARTKNDENECEPLSKSAEMFITNGNRLHL--MSLENSQVSVLRPVFNIKMNLIPG 2593
C GYA D + C+ ++ E F+ NR +L ++L+ S ++L+ N + L
Sbjct: 3008 CVEGYAPRGGDPHSCKAVTDE-EPFLIFANRYYLRKLNLDGSNYTLLKQGLNNAVAL--- 3063
Query: 2592 GIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGL-----ITYDFMH 2428
DF Y R ++Y + IR L GS + GL + D++
Sbjct: 3064 --DFDY---REQMIYWTDVTTQGSMIRRMH----LNGSNVQVLHRTGLSNPDGLAVDWVG 3114
Query: 2427 NNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTT 2248
N+Y+ + I V+K L+ + +L VD ++WT
Sbjct: 3115 GNLYWCDKGRDT----------IEVSKLNGAYRTVLVSSGLREPRALVVDVQNGYLYWTD 3164
Query: 2247 SAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRT 2068
I +DG +V+ I P + +D+ ER+YW D +
Sbjct: 3165 WGDHSLIGRIGMDGSG-----------RSIIVDTKITWPNGLTVDYVTERIYWADAREDY 3213
Query: 2067 IETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGK-------- 1915
IE S DG +R V ++ + + Y+Y SI+R HK TG
Sbjct: 3214 IEFASLDGSNRHVVLSQDIPHI-FALTLFEDYVYWTDWETKSINRAHKTTGANKTLLIST 3272
Query: 1914 -------------------------TNKYVQKIREVSPRIQIRVAHP--------AKHTV 1834
N + +SP + A P + V
Sbjct: 3273 LHRPMDLHVFHALRQPDVPNHPCKVNNGGCSNLCLLSPGGGHKCACPTNFYLGGDGRTCV 3332
Query: 1833 SHITHQKNPCQSDYC-PSNTVCVPDQDKNGIL-----IPKCLCGPGRFFEVSTKKCMQLR 1672
S+ T + C++D C P C + D P+ C PG+ F+ ST C
Sbjct: 3333 SNCTASQFVCKNDKCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQ-FQCSTGIC---- 3387
Query: 1671 EKDQEASQC-GDYFCYNNAGCSPQKTCVCPPGFYGRQCEINEC---------SETCWNGE 1522
A C GD C +N+ + VC P + + N C + C +GE
Sbjct: 3388 --TNPAFICDGDNDCQDNSDEANCDIHVCLPSQF-KCTNTNRCIPGIFRCNGQDNCGDGE 3444
Query: 1521 --------TCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPH 1366
TCA +F + C P + N C +C + C DE
Sbjct: 3445 DERDCPEVTCAPNQFQCSITKRC-IPRVWVCD--RDNDCVDGSDEPANCTQMTCGVDEFR 3501
Query: 1365 CRSYSFC---------ECDKGWTGPHCRHKADAKVCYGH---CFSGGACDGEGPLNLRCS 1222
C+ C E D G + + D + C + C + G +
Sbjct: 3502 CKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCKNNRCVPGRWQCDYDND 3561
Query: 1221 CGDGLTGNRCQ---------NCVGHECLNGGF-------CSYANSNRS-LPHC-----IC 1108
CGD C +C C+ G + C+ + + P C C
Sbjct: 3562 CGDNSDEESCTPRPCSESEFSCANGRCIAGRWKCDGDHDCADGSDEKDCTPRCDMDQFQC 3621
Query: 1107 PSGF---------TGDHCEEYLCKDACPFGSKCTYDITKPMDPITCS---CEQNA--AAH 970
SG C + ++AC G + T P+D C+ C+ A
Sbjct: 3622 KSGHCIPLRWRCDADADCMDGSDEEACGTGVR-----TCPLDEFQCNNTLCKPLAWKCDG 3676
Query: 969 NTDCSPICQKQPNWCHNGGRCLDTPGYPGKCK----CLPRFAGPRCDVPVQCDDYCTNNS 802
DC + P C R + P P +CK CL + G +CD C D T+
Sbjct: 3677 EDDCGDNSDENPEEC---ARFICPPNRPFRCKNDRVCL--WIGRQCDGVDNCGD-GTDEE 3730
Query: 801 KCTITNGTHFECDCKPGF---------KGLRCEQETKCSECSNEAKCIKKPSGTVICQCP 649
C + C K F LRC C + S+E C P
Sbjct: 3731 DCEPPTAQNPHCKDKKEFLCRNQRCLSSSLRCNMFDDCGDGSDEEDCSIDP--------- 3781
Query: 648 QGLGGEYCEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSSNACE-- 475
K+T+ + + C + C++ + +A C C GF + C+
Sbjct: 3782 ---------KLTSCATNASMCGDEARCVRTEKAA-----YCACRSGFH-TVPGQPGCQDI 3826
Query: 474 NFCLHDGNCTL---DEYFEPQCECYQAFI--GDRCQYRIHQHAVIFSDDDS 337
N CL G C+ + C C + F+ + C+ ++ V++ DD+
Sbjct: 3827 NECLRFGTCSQLCNNTKGGHLCSCARNFMKTHNTCKAEGSEYQVLYIADDN 3877
Score = 335 bits (858), Expect = 1e-89
Identities = 308/1243 (24%), Positives = 494/1243 (38%), Gaps = 88/1243 (7%)
Frame = -1
Query: 5259 HLSPYDKKTCLRSPSCPK------ANCSHFCI-DRRDVGHQCFCAPGYILSENQKDCRRN 5101
H+ ++ +RS +C CS C+ C C G+ L + K C++
Sbjct: 464 HIYHQRRQPRVRSHACENDQYGKPGGCSDICLLANSHKARTCRCRSGFSLGSDGKSCKKP 523
Query: 5100 DTIEAEILMVYGHRLK--LFTIDGHAKAT-----LLSNLTNGVALDYDVKSDLVYWTDVA 4942
E E+ +VYG + +D AK + NL N ALD+ ++ +Y+ D
Sbjct: 524 ---EHELFLVYGKGRPGIIRGMDMGAKVPDEHMIPIENLMNPRALDFHAETGFIYFADTT 580
Query: 4941 HDGNKAGITSMSNQPNTYR-VINSLPTKGIDGIAVDWLGRNIYYTD---RNHDAIAVCDM 4774
+ + T R I ++G+AVDW+G N+Y+TD + ++A +
Sbjct: 581 -----SYLIGRQKIDGTERETILKDGIHNVEGVAVDWMGDNLYWTDDGPKKTISVARLEK 635
Query: 4773 RGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDW------GASAHIGRMNMDGSNEQVIL 4612
+ + L++G + PRAIV+DPL ++WTDW + R MDGS+ + +
Sbjct: 636 AAQTRKTLIEGK-MTHPRAIVVDPLNGWMYWTDWEEDPKDSRRGRLERAWMDGSHRDIFV 694
Query: 4611 QDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRG-SVRHIFALAVFED 4435
+T+ WPN L++D PA RLY+ DA D I + +G+ R++V G + H F L +
Sbjct: 695 TSKTVLWPNGLSLDIPAGRLYWVDAFYDRIETILLNGTDRKIVYEGPELNHAFGLCHHGN 754
Query: 4434 YVYWSDWHNHTIERVHK-ITGTNRKVLIQDKQYRPM-GFKIVHPSLQSMGSLKTARHPCS 4261
Y++W+++ + ++ R+ + + G V + + P+ ++ Q +G+ K
Sbjct: 755 YLFWTEYRSGSVYRLERGVAGAPPTVTLLRSERPPIFEIRMYDAQQQQVGTNKCR----V 810
Query: 4260 QPARCDNLCIPANTPDLTTSSDNFTCMCAQGFRSEGRSCVS--------ECKPNDFVCTK 4105
C +LC+ T S C Q ++G +C++ +C+P +F C
Sbjct: 811 NNGGCSSLCL------ATPGSRQCACAEDQVLDTDGVTCLANPSYVPPPQCQPGEFACAN 864
Query: 4104 TYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKL 3925
+CI W+
Sbjct: 865 N-RCIQERWK-------------------------------------------------- 873
Query: 3924 CDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELN--C 3751
CDG DC DE PA C C +FKC + +CIP +CD + DC + DE N C
Sbjct: 874 CDGDNDCLDNSDEAPALCHQHTCPSDRFKC-ENNRCIPNRWLCDGDNDCGNSEDESNATC 932
Query: 3750 EITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSG 3571
+C P+ F+C +G +CIP + CD +DDC + DE SC QF C +G
Sbjct: 933 SARTCPPNQFSCASG----RCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNG 988
Query: 3570 KCIPKRRQCDGTLDCRDGSDEKGCKKECA---IVCDNS-CVHADDLCDGKKKCNDGSDED 3403
+CI +CD DC D SDE GC C+ C++ C+ CDG C D SDE
Sbjct: 989 RCININWRCDNDNDCGDNSDEAGCSHSCSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDET 1048
Query: 3402 EEACVIKQLLEKENRKCGG------------------FACDGIVDCEDGSDEKGCPDL-- 3283
C + R GG + CDG DC D SDEK C +
Sbjct: 1049 HANCT-----NQATRPPGGCHSDEFQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTH 1103
Query: 3282 -----------ECHLASNKSLICDGTIDCSSGKDENNCHNNG-ESNFFQCSMQT---IKE 3148
+ +K+ +CDG DC DE NC C+ T +
Sbjct: 1104 VCDPNVKFGCKDSARCISKAWVCDGDSDCEDNSDEENCEALACRPPSHPCANNTSVCLPP 1163
Query: 3147 WQVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDE 2968
++CDG+ DC DG DE E+C G C +C GSD
Sbjct: 1164 DKLCDGKDDCGDGSDEG-ELCDQCS---LNNGGCSHNCSVAPGEGIVCSCPLGMELGSDN 1219
Query: 2967 NPIHCKDMCKGKYRCTNGRCIDVSARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAF 2788
+ + C + C+QKC
Sbjct: 1220 HTCQIQSYCAKHLK-------------------------------------CSQKCDQN- 1241
Query: 2787 NHTARCHCAPGYARTKNDENECEPLSKSAEMFI-TNGNRLHLMSLENSQVSVLRPVFNIK 2611
+ +C C G+ + D C L I +N + + + L SVL P
Sbjct: 1242 KFSVKCSCYEGWV-LEPDGESCRSLDPFKPFIIFSNRHEIRRIDLHKGDYSVLVPGLR-- 1298
Query: 2610 MNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGLIT---- 2443
N I +DF + +Y + ++ R K +G + S+ E GL T
Sbjct: 1299 -NTI--ALDFH---LSQSALYWTDVVEDKI-YRGKLLDNGALTSF-EVVIQYGLATPEGL 1350
Query: 2442 -YDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKR 2266
D++ N+Y+ ES+ I VAK T TL+ ++A+DP
Sbjct: 1351 AVDWIAGNIYWVESNLD----------QIEVAKLDGTLRTTLLAGDIEHPRAIALDPRDG 1400
Query: 2265 LIFWTT-SAPVPRILSANLDG---KPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNER 2098
++FWT A +PRI +A++ G + I + +G P+ + +D+ +R
Sbjct: 1401 ILFWTDWDASLPRIEAASMSGAGRRTIHRETGSGGWPN------------GLTVDYLEKR 1448
Query: 2097 LYWIDVLKRTIETVSFDGRDRRTV-RKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKF 1924
+ WID I + +DG V R E P + + GG +Y R ++ + +K+
Sbjct: 1449 ILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYGGEVYWTDWRTNTLAKANKW 1508
Query: 1923 TGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSD 1795
TG VQ R + ++V HP++ ++ NPC+++
Sbjct: 1509 TGHNVTVVQ--RTNTQPFDLQVYHPSRQPMA-----PNPCEAN 1544
Score = 203 bits (517), Expect = 4e-50
Identities = 149/518 (28%), Positives = 239/518 (45%), Gaps = 26/518 (5%)
Frame = -1
Query: 5619 RQCKPNEWMC-DSGQCIDSGRLCDASVDCVDGSDEWVEICSLSEPPRRGCPSG-WSCLLT 5446
+ C P ++ C D CI G CD DC DGSDE EIC S+ R CP SCL
Sbjct: 26 KTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQR--CPPNEHSCL-- 81
Query: 5445 NGTIGCLQEQQLCDGRRDCMSGIDE--QCDNPQGNCSSTRNSCDQTWNCQRHAGFESCSC 5272
GT C+ +LC+G +DCM G DE C + NCS R C +C +C C
Sbjct: 82 -GTELCVPMSRLCNGIQDCMDGSDEGAHCRELRANCS--RMGCQH--HCVPTPSGPTCYC 136
Query: 5271 DDGYHLSPYDKKTCLRSPSCPK-ANCSHFCIDRRDVGHQCFCAPGYILSENQKDCR-RND 5098
+ + L D KTC C CS C + D C C GY+L + + C+ +N+
Sbjct: 137 NSSFQLQA-DGKTCKDFDECSVYGTCSQLCTNT-DGSFTCGCVEGYLLQPDNRSCKAKNE 194
Query: 5097 TIEAEILMVYGHRLKLFT--IDGHAKATLLSNLTNGV-ALDYDVKSDLVYWTDVAHDGNK 4927
++ +++ + + + G +T+ T A+D+ ++ V W V +
Sbjct: 195 PVDRPPVLLIANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWVHVGDSAAQ 254
Query: 4926 -----AGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRF 4762
A + + + + + SL ++ +A+DWL N Y+ D D I VC+ G
Sbjct: 255 TQLKCARMPGLKGFVDEHTINISLSLHHVEQMAIDWLTGNFYFVDDIDDRIFVCNRNGD- 313
Query: 4761 NRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNA 4582
+ L L +P+ I LDP VF+TD+G + R +MDG N + L D I +P+
Sbjct: 314 TCVTLLDLELYNPKGIALDPAMGKVFFTDYGQIPKVERCDMDGQN-RTKLVDSKIVFPHG 372
Query: 4581 LAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRG-SVRHIFALAVFEDYVYWSDWHNH 4405
+ +D ++ +Y+ DA+ DYI +Y+G R+ +++G + H++ L VFE+Y+Y ++ N
Sbjct: 373 ITLDLVSRLVYWADAYLDYIEVVDYEGKGRQTIIQGILIEHLYGLTVFENYLYATNSDNA 432
Query: 4404 TIERVHKITGTNR----KVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPC-----SQPA 4252
++ + NR + + + + I H Q + H C +P
Sbjct: 433 NTQQKTSVIRVNRFNSTEYQVVTRVDKGGALHIYHQRRQP----RVRSHACENDQYGKPG 488
Query: 4251 RCDNLCIPANTPDLTTSSDNFTCMCAQGFR--SEGRSC 4144
C ++C+ AN S TC C GF S+G+SC
Sbjct: 489 GCSDICLLAN------SHKARTCRCRSGFSLGSDGKSC 520
Score = 174 bits (440), Expect = 3e-41
Identities = 103/277 (37%), Positives = 134/277 (48%), Gaps = 10/277 (3%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADES-NC---TCNE-NEFR 6409
+DE CS R C P F+C +G CIP C+ +DC + +DES +C TC +F
Sbjct: 925 EDESNATCSARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQFT 984
Query: 6408 CQSGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKC 6229
C +G CI RC++ DC D SDE GC +CS+ C + +CI W C
Sbjct: 985 CNNGRCININWRCDNDNDCGDNSDEAGCS-HSCSSTQ-------FKC-NSGRCIPEHWTC 1035
Query: 6228 DGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCA 6049
DG NDC D SDE + T + P C + +F C C+P W+CDG DC
Sbjct: 1036 DGDNDCGDYSDE----THANCTNQATRPPGGCHS-DEFQCRLDGLCIPLRWRCDGDTDCM 1090
Query: 6048 DGSDEKNCD--AKKC-TSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGG 5878
D SDEK+C+ C + +F C+ S +CI CDG DC D DE CE
Sbjct: 1091 DSSDEKSCEGVTHVCDPNVKFGCKDSARCISKAWVCDGDSDCEDNSDEENCEALACRPPS 1150
Query: 5877 NATFRCTNHR--CIPMAWRCDGTDDCMDNAKSLGSDE 5773
+ C N+ C+P CDG DDC D GSDE
Sbjct: 1151 HP---CANNTSVCLPPDKLCDGKDDCGD-----GSDE 1179
Score = 155 bits (393), Expect = 1e-35
Identities = 110/387 (28%), Positives = 180/387 (46%), Gaps = 15/387 (3%)
Frame = -1
Query: 5259 HLSPYDKKTCLRSP-----SCPKANCSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDT 5095
H+ YD+ L S +CS C+ + C C GY L Q+ C +
Sbjct: 1833 HMKVYDESIQLEHEGTNPCSVNNGDCSQLCLPTSETTRSCMCTAGYSLRSGQQAC---EG 1889
Query: 5094 IEAEILMVYGHRLKLFTIDGHAKATLL---SNLTNGVALDYDVKSDLVYWTDVAHDGNKA 4924
+ + +L ++ +D + K+ L S + V +D+ ++D +YW D+
Sbjct: 1890 VGSFLLYSVHEGIRGIPLDPNDKSDALVPVSGTSLAVGIDFHAENDTIYWVDM------- 1942
Query: 4923 GITSMSNQPNTYRVINSLPTKGI---DGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRI 4753
G++++S + T GI +GIAVDW+ NIY+TD+ D I V + G F +
Sbjct: 1943 GLSTISRAKRDQTWREDVVTNGIGRVEGIAVDWIAGNIYWTDQGFDVIEVARLNGSFRYV 2002
Query: 4752 LLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAV 4573
++ L+ PRAI + P + +FWT+WG I R +DG+ E+V+L + +I WPN ++V
Sbjct: 2003 VI-SQGLDKPRAITVHPEKGYLFWTEWGHYPRIERSRLDGT-ERVVLVNVSISWPNGISV 2060
Query: 4572 DAPAQRLYFGDAHRDYIASCNYD-GSKRRMVLRGSVRHIFALAVFEDYVYWSD--WHNHT 4402
D +LY+ DA D I + + G R +VL + +F+++VFED++YWSD N +
Sbjct: 2061 DYQGGKLYWCDARMDKIERIDLETGENREVVLSSNNMDMFSVSVFEDFIYWSDRTHANGS 2120
Query: 4401 IERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDNLCIPAN 4222
I+R K T+ L + K+ + Q ++ + C LC
Sbjct: 2121 IKRGCKDNATDSVPLRTGIGVQLKDIKVFNRDRQKGTNVCAVAN-----GGCQQLC---- 2171
Query: 4221 TPDLTTSSDNFTCMCAQGFRSE-GRSC 4144
L C CA G +E G SC
Sbjct: 2172 ---LYRGGGQRACACAHGMLAEDGASC 2195
Score = 129 bits (324), Expect = 1e-27
Identities = 97/365 (26%), Positives = 166/365 (44%), Gaps = 13/365 (3%)
Frame = -1
Query: 5199 CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAK-- 5026
CSH C+ + C C L ++ C E + ++Y ++++ +D A
Sbjct: 1550 CSHLCLINYNRTVSCACPHLMKLHKDNTTC-----YEFKKFLLYARQMEIRGVDLDAPYY 1604
Query: 5025 ----ATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKG 4858
+ + ++ N LDYD + VYW+DV K + + + S
Sbjct: 1605 NYIISFTVPDIDNVTVLDYDAREQRVYWSDVRTQAIKRAFINGTG----VETVVSADLPN 1660
Query: 4857 IDGIAVDWLGRNIYYT--DRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVF 4684
G+AVDW+ RN+++T D N I V + G F +++G L P +V+ PL+ ++
Sbjct: 1661 AHGLAVDWVSRNLFWTSYDTNKKQINVARLDGSFKNAVVQG--LEQPHGLVVHPLRGKLY 1718
Query: 4683 WTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYD 4504
WTD +I NMDGSN ++ + + P LA+D P +LY+ + I CN D
Sbjct: 1719 WTD---GDNISMANMDGSNHTLLFSGQ--KGPVGLAIDFPESKLYWISSGNHTINRCNLD 1773
Query: 4503 GSKRRMV--LRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPM 4330
GS+ ++ +R + ALA+ D ++W+D + + +K G+ V++++ M
Sbjct: 1774 GSELEVIDTMRSQLGKATALAIMGDKLWWADQVSEKMGTCNKADGSG-SVVLRNSTTLVM 1832
Query: 4329 GFKIVHPSLQSMGSLKTARHPCS-QPARCDNLCIPANTPDLTTSSDNFTCMCAQGF--RS 4159
K+ S+Q +PCS C LC+P TS +CMC G+ RS
Sbjct: 1833 HMKVYDESIQLE---HEGTNPCSVNNGDCSQLCLP-------TSETTRSCMCTAGYSLRS 1882
Query: 4158 EGRSC 4144
++C
Sbjct: 1883 GQQAC 1887
Score = 128 bits (322), Expect = 2e-27
Identities = 91/341 (26%), Positives = 129/341 (37%)
Frame = -1
Query: 1173 ECLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCS 994
+C NGG C + N+ R P C C +TGD CE C +
Sbjct: 4204 QCFNGGSC-FLNARRQ-PKCRCQPRYTGDKCELDQCWE---------------------- 4239
Query: 993 CEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYC 814
+CHNGG C +P C+C F GP+C V C YC
Sbjct: 4240 ---------------------YCHNGGTCAASPSGMPTCRCPTGFTGPKCTAQV-CAGYC 4277
Query: 813 TNNSKCTITNGTHFECDCKPGFKGLRCEQETKCSECSNEAKCIKKPSGTVICQCPQGLGG 634
+NNS CT+ G +C C PGF G RC+ C N C G+ C+C G
Sbjct: 4278 SNNSTCTVNQGNQPQCRCLPGFLGDRCQYRQCSGFCENFGTCQMAADGSRQCRCTVYFEG 4337
Query: 633 EYCEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCLHDG 454
CE + C Q G C+ + + TC C+ G C + C + C + G
Sbjct: 4338 PRCEVNKCSRCLQ------GACVVNKQTGD---VTCNCTDGRVAPSCLT--CIDHCSNGG 4386
Query: 453 NCTLDEYFEPQCECYQAFIGDRCQYRIHQHAVIFSDDDSGWIKSFXXXXXXXXXXXXXXX 274
+CT++ P+C+C G RC+ + + S G + S
Sbjct: 4387 SCTMNSKMMPECQCPPHMTGPRCEEQ------VVSQQQPGHMASILIPLLLLLLLLLVAG 4440
Query: 273 IFANRSNRFAVFRQFRHNPLQNQGAPVDQFSNPAYLIDEGG 151
+ R + F+H + N GA + NP Y + EGG
Sbjct: 4441 VVFWYKRRVRGAKGFQHQRMTN-GAMNVEIGNPTYKMYEGG 4480
Score = 116 bits (291), Expect = 6e-24
Identities = 113/465 (24%), Positives = 182/465 (38%), Gaps = 18/465 (3%)
Frame = -1
Query: 3153 KEWQVCDGRWDCADGLDESPEMCASRKA-RCFRIGY-CDDKKQCLDVSTALCDGIRDCFD 2980
K W+ CDG DC DG DE+PE+C KA RC + C + C+ +S LC+GI+DC D
Sbjct: 44 KGWR-CDGERDCPDGSDEAPEICPQSKAQRCPPNEHSCLGTELCVPMS-RLCNGIQDCMD 101
Query: 2979 GSDENPIHCKDMCKGKYRC-TNGRCIDVSARXXXXXXXXXXXXXXXXGA----ECHHFGV 2815
GSDE HC+++ R C+ + EC +G
Sbjct: 102 GSDEG-AHCRELRANCSRMGCQHHCVPTPSGPTCYCNSSFQLQADGKTCKDFDECSVYGT 160
Query: 2814 CAQKCWMAFNHTARCHCAPGYARTKNDENEC----EPLSKSAEMFITNGNRLHLMSLENS 2647
C+Q C + + C C GY + D C EP+ + + I N + L +
Sbjct: 161 CSQLCTNT-DGSFTCGCVEGYL-LQPDNRSCKAKNEPVDRPPVLLIANSQNILATYLSGA 218
Query: 2646 QVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEE 2467
QVS + P + +DF Y T VG ++ ++ + GL G E
Sbjct: 219 QVSTITPTSTRQTT----AMDFSY-ANETVCWVHVGDSAAQTQLKCAR-MPGLKGFVDEH 272
Query: 2466 ESTAGL-------ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNS 2308
L + D++ N YF + D I+V + TL+
Sbjct: 273 TINISLSLHHVEQMAIDWLTGNFYFVD----------DIDDRIFVCNRNGDTCVTLLDLE 322
Query: 2307 TGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPT 2128
+A+DP +F+T +P++ ++DG Q LV+ I P
Sbjct: 323 LYNPKGIALDPAMGKVFFTDYGQIPKVERCDMDG-----------QNRTKLVDSKIVFPH 371
Query: 2127 SMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITRQG 1948
+ LD + +YW D IE V ++G+ R+T+ + L + + V Y+Y
Sbjct: 372 GITLDLVSRLVYWADAYLDYIEVVDYEGKGRQTIIQGILIEHLYGLTVFENYLYATNSDN 431
Query: 1947 SIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQK 1813
+ + + N++ +V R+ K HI HQ+
Sbjct: 432 ANTQQKTSVIRVNRFNSTEYQVVTRVD-------KGGALHIYHQR 469
Score = 107 bits (268), Expect = 3e-21
Identities = 194/881 (22%), Positives = 314/881 (35%), Gaps = 68/881 (7%)
Frame = -1
Query: 2820 GVCAQKCWMAFNHTAR-CHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQ 2644
G C+ C +A +H AR C C G++ +D C+ + G + ++
Sbjct: 488 GGCSDICLLANSHKARTCRCRSGFS-LGSDGKSCKKPEHELFLVYGKGRPGIIRGMDMGA 546
Query: 2643 VSVLRPVFNIKMNLIPGGIDF----GYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSW 2476
+ I+ + P +DF G+ F T Y +G R DG+
Sbjct: 547 KVPDEHMIPIENLMNPRALDFHAETGFIYFADTTSYLIGRQKIDGTERETILKDGIHNVE 606
Query: 2475 GEEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTST--RTLIVNSTG 2302
G + D+M +N+Y+T+ + I VA+ + + +TLI
Sbjct: 607 G--------VAVDWMGDNLYWTDDGPKK---------TISVARLEKAAQTRKTLIEGKMT 649
Query: 2301 TINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSM 2122
++ VDP+ ++WT P+ + G+ + + + GS + + + P +
Sbjct: 650 HPRAIVVDPLNGWMYWTDWEEDPK---DSRRGR-LERAWMDGSHRDIFVTSKTVLWPNGL 705
Query: 2121 VLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT-RQGS 1945
LD RLYW+D IET+ +G DR+ V + + + G Y++ R GS
Sbjct: 706 SLDIPAGRLYWVDAFYDRIETILLNGTDRKIVYEGPELNHAFGLCHHGNYLFWTEYRSGS 765
Query: 1944 IHRMHKFTGKTNKYVQKIREVSPRI-QIRVAHPAKHTV-SHITHQKNPCQSDYC---PSN 1780
++R+ + V +R P I +IR+ + V ++ N S C P +
Sbjct: 766 VYRLERGVAGAPPTVTLLRSERPPIFEIRMYDAQQQQVGTNKCRVNNGGCSSLCLATPGS 825
Query: 1779 TVCVPDQDK-----------NGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCGDYF 1633
C +D+ N +P C PG F + +C+Q R K GD
Sbjct: 826 RQCACAEDQVLDTDGVTCLANPSYVPPPQCQPGE-FACANNRCIQERWKCD-----GDND 879
Query: 1632 CYNNAGCSPQ--KTCVCPPGFYGRQCEINECSETCW---NGETCAVQEFGSTTNVVCH-- 1474
C +N+ +P CP + +CE N C W C E +N C
Sbjct: 880 CLDNSDEAPALCHQHTCPSDRF--KCENNRCIPNRWLCDGDNDCGNSE--DESNATCSAR 935
Query: 1473 -CPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHKAD 1297
CP N Q SCA+ C + + C D+ +C R
Sbjct: 936 TCPPN--QFSCASGRCIPI--------SWTCDLDD---------DCGD-------RSDES 969
Query: 1296 AKVCYGHCF-------SGGACDGEGPLNLRC----SCGDGLTGNRCQNCVGHECLNGGFC 1150
A Y CF + G C +N RC CGD C H C + F
Sbjct: 970 ASCAYPTCFPLTQFTCNNGRCIN---INWRCDNDNDCGDNSDEAGC----SHSCSSTQF- 1021
Query: 1149 SYANSNRSLP-HCICP-SGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCSCEQNAA 976
NS R +P H C GD+ +E + CT T+P P C ++
Sbjct: 1022 -KCNSGRCIPEHWTCDGDNDCGDYSDE--------THANCTNQATRP--PGGCHSDEFQC 1070
Query: 975 AHNTDCSPICQKQPNW-CHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSK 799
+ C P+ W C C+D+ C+ + P +V C D SK
Sbjct: 1071 RLDGLCIPL-----RWRCDGDTDCMDSSD-EKSCEGVTHVCDP--NVKFGCKDSARCISK 1122
Query: 798 CTITNGTHFECDCKPGFKGLRCEQ---ETKCSECSNEAKCIKKPSGTVICQCPQGLGGEY 628
+ +G + DC+ CE C+N P +C G
Sbjct: 1123 AWVCDG---DSDCEDNSDEENCEALACRPPSHPCANNTSVCLPPD--KLCDGKDDCGDGS 1177
Query: 627 CEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCS----------SNAC 478
E C Q NGG S C +PG +G++CS ++ C
Sbjct: 1178 DE---GELCDQCSLNNGG-----------CSHNCSVAPG-EGIVCSCPLGMELGSDNHTC 1222
Query: 477 --ENFCLHDGNCTL---DEYFEPQCECYQAFI----GDRCQ 382
+++C C+ F +C CY+ ++ G+ C+
Sbjct: 1223 QIQSYCAKHLKCSQKCDQNKFSVKCSCYEGWVLEPDGESCR 1263
Score = 89.4 bits (220), Expect = 1e-15
Identities = 43/114 (37%), Positives = 62/114 (53%), Gaps = 5/114 (4%)
Frame = -1
Query: 6165 TGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADGSDE-----KNCDAKKCTSF 6001
+G ++ AP++C K QFAC TC+ K W+CDG+ DC DGSDE A++C
Sbjct: 18 SGATMDAPKTCSPK-QFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPN 76
Query: 6000 EFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNATFRCTNHRCIP 5839
E SC ++ C+P+ + C+G +DC DG DE C N + H C+P
Sbjct: 77 EHSCLGTELCVPMSRLCNGIQDCMDGSDE---GAHCRELRANCSRMGCQHHCVP 127
Score = 69.3 bits (168), Expect = 1e-09
Identities = 55/184 (29%), Positives = 75/184 (39%), Gaps = 15/184 (8%)
Frame = -1
Query: 3858 CTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDEL-----NCEITSCKPDFFACFNGTAIS 3694
C+ QF C D+ CI CD E+DC DGSDE + C P+ +C GT +
Sbjct: 28 CSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEHSCL-GTEL- 85
Query: 3693 KCIPKEFYCDGEDDCPEGQDEPDSCFGIGE------CTHEQFQCTSGKCIPKRRQCDGTL 3532
C+P C+G DC +G DE C + C H SG C+ +
Sbjct: 86 -CVPMSRLCNGIQDCMDGSDEGAHCRELRANCSRMGCQHHCVPTPSGPTC----YCNSSF 140
Query: 3531 DCRDGSDEKGCK--KECAI--VCDNSCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKE 3364
+ +D K CK EC++ C C + DG C CV LL+ +
Sbjct: 141 QLQ--ADGKTCKDFDECSVYGTCSQLCTNT----DGSFTC---------GCVEGYLLQPD 185
Query: 3363 NRKC 3352
NR C
Sbjct: 186 NRSC 189
Score = 63.9 bits (154), Expect = 5e-08
Identities = 75/303 (24%), Positives = 118/303 (38%), Gaps = 8/303 (2%)
Frame = -1
Query: 2820 GVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQV 2641
G C+Q C T C C GY+ ++ + CE + + G R + N +
Sbjct: 1856 GDCSQLCLPTSETTRSCMCTAGYS-LRSGQQACEGVGSFLLYSVHEGIRGIPLD-PNDKS 1913
Query: 2640 SVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEES 2461
L PV + + GIDF + +Y V +G S + R+K+ +W E+
Sbjct: 1914 DALVPVSGTSLAV---GIDFHAE---NDTIYWVDMGLSTIS-RAKRDQ-----TWREDVV 1961
Query: 2460 TAGL-----ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTI 2296
T G+ I D++ N+Y+T+ FD I VA+ + +I
Sbjct: 1962 TNGIGRVEGIAVDWIAGNIYWTDQG-------FDV---IEVARLNGSFRYVVISQGLDKP 2011
Query: 2295 NSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVL 2116
++ V P K +FWT PRI + LDG LV +I P + +
Sbjct: 2012 RAITVHPEKGYLFWTEWGHYPRIERSRLDG-----------TERVVLVNVSISWPNGISV 2060
Query: 2115 DFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITR---QGS 1945
D+ +LYW D IE + + + R V ++ V +IY R GS
Sbjct: 2061 DYQGGKLYWCDARMDKIERIDLETGENREVVLSSNNMDMFSVSVFEDFIYWSDRTHANGS 2120
Query: 1944 IHR 1936
I R
Sbjct: 2121 IKR 2123
Score = 62.0 bits (149), Expect = 2e-07
Identities = 44/157 (28%), Positives = 56/157 (35%), Gaps = 20/157 (12%)
Frame = -1
Query: 6270 CATTSQCIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAK-------TQFA 6112
C CI W+CDG DC DGSDE AP C + +
Sbjct: 35 CRDQITCISKGWRCDGERDCPDGSDE---------------APEICPQSKAQRCPPNEHS 79
Query: 6111 CLATRTCMPKHWQCDGQPDCADGSDE--------KNCDAKKCTSFEFSCESSKKCI---P 5965
CL T C+P C+G DC DGSDE NC C S C
Sbjct: 80 CLGTELCVPMSRLCNGIQDCMDGSDEGAHCRELRANCSRMGCQHHCVPTPSGPTCYCNSS 139
Query: 5964 LEQKCDGR--RDCPDGEDEHQCETECDSKGGNATFRC 5860
+ + DG+ +D + C C + G+ T C
Sbjct: 140 FQLQADGKTCKDFDECSVYGTCSQLCTNTDGSFTCGC 176
Score = 61.6 bits (148), Expect = 2e-07
Identities = 63/255 (24%), Positives = 88/255 (33%), Gaps = 20/255 (7%)
Frame = -1
Query: 5913 HQCETECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVP 5734
HQ C +GG R + + C N+ DE +CA G
Sbjct: 2498 HQGHVNCSCRGG---------RILQEDFTCRAV-----NSSCRAQDEFECANGE------ 2537
Query: 5733 SRCADETCVVACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLC 5554
C ++ CDG+ C D DEK R+CK C++G+C+ + C
Sbjct: 2538 -----------CISFSLTCDGVSHCKDKSDEKPSYCNSRRCKKTFRQCNNGRCVSNMLWC 2586
Query: 5553 DASVDCVDGSDEW---VEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMS 5383
+ DC DGSDE C + E C G C+ C+ DC
Sbjct: 2587 NGVDDCGDGSDEIPCNKTACGVGE---FRCRDG----------SCIGNSSRCNQFVDCED 2633
Query: 5382 GIDEQCDNPQGNCSSTRNS--------------CDQTWNCQRHAGFESCSCDDGYHLSPY 5245
DE NCS+T S C++T C S CD Y
Sbjct: 2634 ASDEM------NCSTTDCSSYFRLGVKGVLFQPCERTSLCYA----PSWVCDGANDCGDY 2683
Query: 5244 -DKKTC--LRSPSCP 5209
D++ C ++ P CP
Sbjct: 2684 SDERDCPGVKRPRCP 2698
Score = 57.4 bits (137), Expect = 5e-06
Identities = 48/184 (26%), Positives = 67/184 (36%), Gaps = 13/184 (7%)
Frame = -1
Query: 4008 PFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFE---CTEAQFK 3838
P C QF C C+ CDG +DC G DE P C + C +
Sbjct: 25 PKTCSPKQFAC-----RDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEHS 79
Query: 3837 CGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCKPDFFACFNGTAISKCIP----KEFY 3670
C + C+P++ +C+ +DC DGSD E C+ C C+P Y
Sbjct: 80 CLGTELCVPMSRLCNGIQDCMDGSD----EGAHCRELRANCSRMGCQHHCVPTPSGPTCY 135
Query: 3669 CDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQCDG--TLDCRDG----SDE 3508
C+ Q + +C EC+ G C DG T C +G D
Sbjct: 136 CNSSFQL---QADGKTCKDFDECS------VYGTCSQLCTNTDGSFTCGCVEGYLLQPDN 186
Query: 3507 KGCK 3496
+ CK
Sbjct: 187 RSCK 190
Score = 52.8 bits (125), Expect = 1e-04
Identities = 78/393 (19%), Positives = 140/393 (34%), Gaps = 14/393 (3%)
Frame = -1
Query: 2820 GVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQV 2641
G C+ C + +N T C C P + D C K L+ +E V
Sbjct: 1548 GPCSHLCLINYNRTVSCAC-PHLMKLHKDNTTCYEFKKFL---------LYARQMEIRGV 1597
Query: 2640 SVLRPVFNIKMNLIPGGID----FGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWG 2473
+ P +N ++ ID YD + ++ D+R++ I G
Sbjct: 1598 DLDAPYYNYIISFTVPDIDNVTVLDYDAREQRVYWS--------DVRTQAIKRAFINGTG 1649
Query: 2472 EEE------STAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVN 2311
E A + D++ N+++T S + N+ +Q N+ D S + +V
Sbjct: 1650 VETVVSADLPNAHGLAVDWVSRNLFWT-SYDTNK-----KQINV---ARLDGSFKNAVVQ 1700
Query: 2310 STGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEP 2131
+ L V P++ ++WT I AN+DG + L+ P
Sbjct: 1701 GLEQPHGLVVHPLRGKLYWTDG---DNISMANMDGS------------NHTLLFSGQKGP 1745
Query: 2130 TSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTV--RKFELGDTPVTMDVLGGYIYLIT 1957
+ +DF +LYWI TI + DG + + + +LG + ++G ++
Sbjct: 1746 VGLAIDFPESKLYWISSGNHTINRCNLDGSELEVIDTMRSQLGKA-TALAIMGDKLWW-- 1802
Query: 1956 RQGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVS-HITHQ-KNPCQSDYCPS 1783
++ + G NK V V H + S + H+ NPC +
Sbjct: 1803 ----ADQVSEKMGTCNKADGSGSVVLRNSTTLVMHMKVYDESIQLEHEGTNPCSVNNGDC 1858
Query: 1782 NTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKC 1684
+ +C+P + C+C G + C
Sbjct: 1859 SQLCLPTSETT----RSCMCTAGYSLRSGQQAC 1887
Score = 52.0 bits (123), Expect = 2e-04
Identities = 49/173 (28%), Positives = 62/173 (35%), Gaps = 6/173 (3%)
Frame = -1
Query: 6432 TCNENEFRCQSG-ACIPSKARCNHMQDCNDASDEIG--CPFRNCSAL--NEFGMTGLINC 6268
TC+ +F C+ CI RC+ +DC D SDE CP NE +C
Sbjct: 27 TCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEH------SC 80
Query: 6267 ATTSQCIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCM 6088
T C+ S C+G DC DGSDE E A + Q C+ T
Sbjct: 81 LGTELCVPMSRLCNGIQDCMDGSDEGAHCRELRANCSRMGC--------QHHCVPT---- 128
Query: 6087 PKHWQCDGQPDC-ADGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDC 5932
P C + S + D K C F+ C C L DG C
Sbjct: 129 ------PSGPTCYCNSSFQLQADGKTCKDFD-ECSVYGTCSQLCTNTDGSFTC 174
Score = 40.4 bits (93), Expect = 0.59
Identities = 34/130 (26%), Positives = 49/130 (37%), Gaps = 10/130 (7%)
Frame = -1
Query: 6570 DEDTKYC---STRVCRPGYFNC-GNGLCIPEQKVCNRINDCANFADESNCTCNENEFRCQ 6403
DE + C + C P +C G LC+P ++CN I DC + +DE C E C
Sbjct: 59 DEAPEICPQSKAQRCPPNEHSCLGTELCVPMSRLCNGIQDCMDGSDE-GAHCRELRANCS 117
Query: 6402 SGAC------IPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHP 6241
C PS C CN +S ++ + C +E C+ C
Sbjct: 118 RMGCQHHCVPTPSGPTCY----CN-SSFQLQADGKTCKDFDE--------CSVYGTCSQL 164
Query: 6240 SWKCDGTNDC 6211
DG+ C
Sbjct: 165 CTNTDGSFTC 174
>gi|34865759|ref|XP_243524.2| similar to lipoprotein receptor-related
protein [Rattus norvegicus]
Length = 4662
Score = 848 bits (2191), Expect = 0.0
Identities = 634/2071 (30%), Positives = 894/2071 (42%), Gaps = 158/2071 (7%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCT---CNENEFRCQS 6400
DE YC++R C+ + C NG C+ CN ++DC + +DE C C EFRC+
Sbjct: 2589 DEKPSYCNSRRCKKTFRQCNNGRCVSNMLWCNGVDDCGDGSDEIPCNKTACGVGEFRCRD 2648
Query: 6399 GACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLI--NCATTSQCIHPSWKCD 6226
G+CI + +RCN DC DASDE+ C +CS+ G+ G++ C TS C PSW CD
Sbjct: 2649 GSCIGNSSRCNQFVDCEDASDEMNCSATDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCD 2708
Query: 6225 GTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCAD 6046
G NDC D SDE+D V PR FAC + R C+P W CD + DC +
Sbjct: 2709 GANDCGDYSDERD--------SPGVKRPRC--PLNYFACPSGR-CIPMSWTCDKEDDCEN 2757
Query: 6045 GSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKG-GNAT 5869
G DE +C+ K C+ +F C+ + +CI + CDG DC DG DE C+ K G ++
Sbjct: 2758 GEDETHCN-KFCSEAQFECQ-NHRCISKQWLCDGSDDCGDGSDE---AAHCEGKTCGPSS 2812
Query: 5868 FRCT-NHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACEL 5692
F C H C+P W CDG DC D A S C T C + C+
Sbjct: 2813 FSCPGTHVCVPERWLCDGDKDCADGADE--SISAGCLYNSTCDDREFMCQNRLCIP---- 2866
Query: 5691 TAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRL-CDASVDCVDGSDEW 5515
+CD +DC+DG DE C PNE+ C +G+C+ S + CD DC D SDE
Sbjct: 2867 KHFVCDHDRDCADGSDESPECEYP-TCGPNEFRCANGRCLSSRQWECDGENDCHDHSDEA 2925
Query: 5514 VEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSST 5335
+ + P + C + L ++G C+ E LC+G+ DC G DE+ + S
Sbjct: 2926 PKNPHCTSPEHK-CNASSQFLCSSGR--CVAEALLCNGQDDCGDGSDERGCHVNECLSRK 2982
Query: 5334 RNSCDQTWNCQ-RHAGFE-SCSCDDGYHLSPYDKKTCLRSPSCPKA-NCSHFCIDRRDVG 5164
+ C Q +C+ GF+ C C G+ L D +TC C CS CI+
Sbjct: 2983 LSGCSQ--DCEDLKIGFKVHCRCRPGFRLKD-DGRTCADVDECSTTFPCSQLCINTHG-S 3038
Query: 5163 HQCFCAPGYI-LSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLTNGVAL 4987
++C C GY + C+ E ++ + L+ +DG L L N VAL
Sbjct: 3039 YKCLCVEGYAPRGGDPHSCKAVTDEEPFLIFANRYYLRKLNLDGSNYTLLKQGLNNAVAL 3098
Query: 4986 DYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTD 4807
D+D + ++YWTDV G+ I M + +V++ DG+AVDW+G N+Y+ D
Sbjct: 3099 DFDYRGQMIYWTDVTTQGSM--IRRMHLNGSNVQVLHRTGLSNPDGLAVDWVGGNLYWCD 3156
Query: 4806 RNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSN 4627
+ D I V + G + R +L + L +PRA+V+D ++WTDWG + IGR+ MDGS
Sbjct: 3157 KGRDTIEVSKLNGAY-RTVLVSSGLREPRALVVDVQNGYLYWTDWGDHSLIGRIGMDGSG 3215
Query: 4626 EQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRM------------- 4486
+I+ D I WPN L VD +R+Y+ DA DYI + DGS R +
Sbjct: 3216 RSIIV-DTKITWPNGLTVDYVTERIYWADAREDYIEFASLDGSNRHVGPYARLRWDSRRS 3274
Query: 4485 -----------------------VLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITG 4375
VL + HIFAL +FEDYVYW+DW +I R HK TG
Sbjct: 3275 GRHGTQSVLGANFCSVSPASPPTVLSQDIPHIFALTLFEDYVYWTDWETKSINRAHKTTG 3334
Query: 4374 TNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCS-QPARCDNLCIPANTPDLTTSS 4198
N+ +LI +RPM + H Q HPC C NLC L +
Sbjct: 3335 ANKTLLI-STLHRPMDLHVFHALRQP----DVPNHPCKVNNGGCSNLC-------LLSPG 3382
Query: 4197 DNFTCMCAQGF--RSEGRSCVSECKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFV 4024
C C F +GR+CVS C + FVC K KCI WW+
Sbjct: 3383 GGHKCACPTNFYLGGDGRTCVSNCTASQFVC-KNDKCIPFWWKCDTEDDCGDHSDE---- 3437
Query: 4023 EGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQ 3844
CP F C GQF C +T C + +CDG DC DE A C+ C +Q
Sbjct: 3438 PPDCPEFKCRPGQFQC------STGICTNPAFICDGDNDCQDNSDE--ANCDIHVCLPSQ 3489
Query: 3843 FKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCKPDFFACFNGTAISKCIPKEFYCD 3664
FKC + +CIP C+ + +C DG DE +C +C P+ F C + +CIP+ + CD
Sbjct: 3490 FKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTCAPNQFQC---SITKRCIPRVWVCD 3546
Query: 3663 GEDDCPEGQDEPDSCFGIGECTHEQFQC-TSGKCIPKRRQCDGTLDCRDGSDEKGCKKEC 3487
++DC +G DEP +C + C ++F+C SG+CIP R +CDG DC DGSDE K+EC
Sbjct: 3547 RDNDCVDGSDEPANCTQM-TCGVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEP--KEEC 3603
Query: 3486 -AIVCD--------NSCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKE----NRKC-- 3352
C+ N CV CD C D S DEE+C + E E N +C
Sbjct: 3604 DERTCEPYQFRCKNNRCVPGRWQCDYDNDCGDNS--DEESCTPRPCSESEFSCANGRCIA 3661
Query: 3351 GGFACDGIVDCEDGSDEKGCP---DLECHLASNKSLI-----CDGTIDCSSGKDENNCHN 3196
G + CDG DC DGSDEK C D++ + I CD DC G DE C
Sbjct: 3662 GRWKCDGDHDCADGSDEKDCTPRCDMDQFQCKSGHCIPLRWRCDADADCMDGSDEEACGT 3721
Query: 3195 NGES---NFFQCSMQTIK--EWQVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQ 3031
GE+ + FQC+ K W+ CDG DC D DE+PE C + R C + +
Sbjct: 3722 GGETCPLDEFQCNNTLCKPLAWK-CDGEDDCGDNSDENPEECTRFQCPPNRPFRCKNDRV 3780
Query: 3030 CLDVSTALCDGIRDCFDGSDE---------NPIHCKDMCKGKYRCTNGRCIDVSARXXXX 2878
CL + CDG +C DG+DE NP HCKD K ++ C N RC+ S R
Sbjct: 3781 CLWIGRQ-CDGTDNCGDGTDEEDCEPPTAQNP-HCKD--KKEFLCRNQRCLSSSLRCNMF 3836
Query: 2877 XXXXXXXXXXXXGAE------CHHFGVCAQKC-WMAFNHTARCHCAPGYARTK-----ND 2734
+ + +C + + A C C PG+ D
Sbjct: 3837 DDCGDGSDEEDCSIDPKLTSCATNASMCGDEARCVRTEKAAYCACRPGFHTVPGQPGCQD 3896
Query: 2733 ENECEPLSKSAEMFITNGNRLHLMS-------------LENSQVSVLRPVFNIKM-NLIP 2596
NEC +++ N HL S E S+ VL + ++ +L P
Sbjct: 3897 INECLRFGTCSQL-CNNTKGGHLCSCARNFMKTHNTCKAEGSEYQVLYIADDNEIRSLFP 3955
Query: 2595 GGIDFGYD-VFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGL---------- 2449
G Y+ F+ + + V W++ G+
Sbjct: 3956 GHPHSAYEQAFQGDESVRIDAMDVHVKAGRVYWTNWHTGTISYRSLPPAAPPTTSNRHRR 4015
Query: 2448 -ITYDFMHNNVYFTESSEQNRGVLFDRQA-NIY----------VAKAKDTSTRTLIVNST 2305
I H N+ + RG+ D A N+Y VA+ K + +TLI
Sbjct: 4016 QIDRGVTHLNI---SGLKMPRGIAIDWVAGNVYWTDSGRDVIEVAQMKGENRKTLISGMI 4072
Query: 2304 GTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTS 2125
+++ VDP++ ++W+ P+I +A +DG + LV+ NI PT
Sbjct: 4073 DEPHAIVVDPLRGTMYWSDWGNHPKIETAAMDG-----------TLRETLVQDNIQWPTG 4121
Query: 2124 MVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELG-DTPVTMDVLGGYIYLITR-Q 1951
+ +D+ NERLYW D I ++ +G D + G P ++DV YIY +T
Sbjct: 4122 LAVDYHNERLYWADAKLSVIGSIRLNGTDPIVAVDSKRGLSHPFSIDVFEDYIYGVTYIN 4181
Query: 1950 GSIHRMHKFTGKTNKYVQKIREVSPRIQIR--VAHPAKHTVSHITHQ---KNPCQSDYCP 1786
+ ++HKF SP I + ++H + + H Q NPC C
Sbjct: 4182 NRVFKIHKFGH------------SPLINLTGGLSHASDVVLYHQHKQPEVTNPCDRKKCE 4229
Query: 1785 SNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCG--DYFCYNNAGC 1612
+ P P C C G+ + T + +A + G C+N C
Sbjct: 4230 WLCLLSPSG-------PVCTCPNGKRLDNGTCVPVPSPTPPPDAPRPGTCTLQCFNGGSC 4282
Query: 1611 ----SPQKTCVCPPGFYGRQCEINECSETCWNGETCAVQEFGSTTNVVCHCPSNYTQSSC 1444
Q C C P + G +CE+++C E C NG TCA G T C CP+ +T C
Sbjct: 4283 FLNARRQPKCRCQPRYTGDKCELDQCWEYCHNGGTCAASPSGMPT---CRCPTGFTGPRC 4339
Query: 1443 ATNVCEGVCGPRGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHK----ADAKVCYGH 1276
VC G C +C ++P CR C G+ G C+++ + G
Sbjct: 4340 TQQVCAGYCANNSTCTV--NQGNQPQCR------CLPGFLGDRCQYREYSPQPQRRKRGA 4391
Query: 1275 CFSGGACDGEGPLNLRCSCGDGLTGNRCQNCVGH---ECLNGGFCSYANSNRSLPHCICP 1105
G+ G P S G + + G C N G C A C C
Sbjct: 4392 GTQRGSSRGWKPSADEPSPGLWVLPPTLAHLPGQCSGFCENFGTCQMAADGSR--QCRCT 4449
Query: 1104 SGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCSCEQNAAAHNTDCSPICQKQPNWC 925
F G CE C C G+ C + K +TC+C A P C + C
Sbjct: 4450 VYFEGTRCEVNKC-SRCLQGA-CV--VNKQTGDVTCNCTDGRVA------PSCLTCIDHC 4499
Query: 924 HNGGRCLDTPGYPGKCKCLPRFAGPRCDVPV 832
NGG C +C+C P GPRC+ V
Sbjct: 4500 SNGGSCTMNSKMMPECQCPPHMTGPRCEEQV 4530
Score = 378 bits (971), Expect = e-103
Identities = 268/855 (31%), Positives = 378/855 (43%), Gaps = 39/855 (4%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGN-GLCIPEQKVCNRINDCANFADESNC---TCNENEFRC 6406
D+ D C VC P F C N CIP CN ++C + DE +C TC N+F+C
Sbjct: 3473 DNSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTCAPNQFQC 3532
Query: 6405 Q-SGACIPSKARCNHMQDCNDASDE-IGCPFRNCSALNEFGMTGLINCATTSQCIHPSWK 6232
+ CIP C+ DC D SDE C C ++EF C + +CI WK
Sbjct: 3533 SITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTC-GVDEF------RCKDSGRCIPARWK 3585
Query: 6231 CDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKT----QFACLATRTCMPKHWQCDG 6064
CDG +DC DGSDE CD +T QF C R C+P WQCD
Sbjct: 3586 CDGEDDCGDGSDE---------------PKEECDERTCEPYQFRCKNNR-CVPGRWQCDY 3629
Query: 6063 QPDCADGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSK 5884
DC D SDE++C + C+ EFSC ++ +CI KCDG DC DG DE C CD
Sbjct: 3630 DNDCGDNSDEESCTPRPCSESEFSC-ANGRCIAGRWKCDGDHDCADGSDEKDCTPRCDMD 3688
Query: 5883 GGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVV 5704
F+C + CIP+ WRCD DCMD GSDE C G + + + T
Sbjct: 3689 ----QFQCKSGHCIPLRWRCDADADCMD-----GSDEEACGTGGETCPLDEFQCNNT--- 3736
Query: 5703 ACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNE-WMCDSGQ-CIDSGRLCDASVDCVD 5530
C+ A CDG DC D DE QC PN + C + + C+ GR CD + +C D
Sbjct: 3737 LCKPLAWKCDGEDDCGDNSDENPEECTRFQCPPNRPFRCKNDRVCLWIGRQCDGTDNCGD 3796
Query: 5529 GSDEWVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQ---CDN 5359
G+DE E C C L N CL C+ DC G DE+ D
Sbjct: 3797 GTDE--EDCEPPTAQNPHCKDKKEFLCRNQR--CLSSSLRCNMFDDCGDGSDEEDCSIDP 3852
Query: 5358 PQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSP-----YDKKTCLRSPSCPKANCS 5194
+C++ + C C R C+C G+H P D CLR CS
Sbjct: 3853 KLTSCATNASMCGDEARCVRTEKAAYCACRPGFHTVPGQPGCQDINECLRF-----GTCS 3907
Query: 5193 HFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLL 5014
C + + GH C CA ++ + N C+ + E ++L + GH +
Sbjct: 3908 QLCNNTKG-GHLCSCARNFMKTHN--TCKAEGS-EYQVLYIADDNEIRSLFPGHPHSAYE 3963
Query: 5013 SNLTNGV-----ALDYDVKSDLVYWTDVAHDGN---------KAGITSMSNQPNTYRVIN 4876
A+D VK+ VYWT+ H G TS ++ R +
Sbjct: 3964 QAFQGDESVRIDAMDVHVKAGRVYWTN-WHTGTISYRSLPPAAPPTTSNRHRRQIDRGVT 4022
Query: 4875 SLPTKGID---GIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLD 4705
L G+ GIA+DW+ N+Y+TD D I V M+G + L+ G +++P AIV+D
Sbjct: 4023 HLNISGLKMPRGIAIDWVAGNVYWTDSGRDVIEVAQMKGENRKTLISGM-IDEPHAIVVD 4081
Query: 4704 PLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDY 4525
PL+ ++W+DWG I MDG+ + ++QD I+WP LAVD +RLY+ DA
Sbjct: 4082 PLRGTMYWSDWGNHPKIETAAMDGTLRETLVQD-NIQWPTGLAVDYHNERLYWADAKLSV 4140
Query: 4524 IASCNYDGSKRRMVL--RGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQ 4351
I S +G+ + + + + H F++ VFEDY+Y + N+ + ++HK G + + +
Sbjct: 4141 IGSIRLNGTDPIVAVDSKRGLSHPFSIDVFEDYIYGVTYINNRVFKIHKF-GHSPLINLT 4199
Query: 4350 DKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDNLCIPANTPDLTTSSDNFTCMCAQ 4171
+ H Q +PC + +C+ LC+ S C C
Sbjct: 4200 GGLSHASDVVLYHQHKQ-----PEVTNPCDR-KKCEWLCL--------LSPSGPVCTCPN 4245
Query: 4170 GFRSEGRSCVSECKP 4126
G R + +CV P
Sbjct: 4246 GKRLDNGTCVPVPSP 4260
Score = 374 bits (960), Expect = e-101
Identities = 267/850 (31%), Positives = 363/850 (42%), Gaps = 54/850 (6%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCI--PEQKVCNRINDCANFADESNCT----------C 6427
D + T CR C + LC+ P + C D AD C C
Sbjct: 813 DAQQQQVGTNKCRVNNGGCSS-LCLATPGSRQCACAEDQVLDADGVTCLANPSYVPPPQC 871
Query: 6426 NENEFRCQSGACIPSKARCNHMQDCNDASDEIG--CPFRNCSALNEFGMTGLINCATTSQ 6253
EF C + CI + +C+ DC D SDE C C + C ++
Sbjct: 872 QPGEFACANNRCIQERWKCDGDNDCLDNSDEAPALCHQHTCPS-------DRFKCEN-NR 923
Query: 6252 CIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKT----QFACLATRTCMP 6085
CI W CDG NDC + DE + +C A+T QF+C + R C+P
Sbjct: 924 CIPNRWLCDGDNDCGNSEDESNA---------------TCSARTCPPNQFSCASGR-CIP 967
Query: 6084 KHWQCDGQPDCADGSDEK-NCDAKKCTSF-EFSCESSKKCIPLEQKCDGRRDCPDGEDEH 5911
W CD DC D SDE +C C +F+C + + CI + +CD +DC DG DE
Sbjct: 968 ISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNGR-CININWRCDNEKDCGDGSDEK 1026
Query: 5910 QC-------------ETECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEV 5770
C E C + F+C + RCIP W CDG +DC D SDE
Sbjct: 1027 TCPEPADNDCGDNSDEAGCSHSCSSTQFKCNSGRCIPEHWTCDGDNDCGDY-----SDET 1081
Query: 5769 DCAAGRTSFHVPSRCADETCVVACELTAVL------CDGIQDCSDGFDEKNCASLDRQCK 5608
+ P C + C L + CDG DC D DEK C + C
Sbjct: 1082 HANCTNQATRPPGGCHSDE--FQCRLDGLCIPLRWRCDGDTDCMDSSDEKGCEGVTHVCD 1139
Query: 5607 PN-EWMC-DSGQCIDSGRLCDASVDCVDGSDEWVEICSLSEPPRRGCPSGWSCLLTNGTI 5434
PN ++ C DS +CI +CD DC D SDE PP C N T
Sbjct: 1140 PNVKFGCKDSARCISKAWVCDGDSDCEDNSDEENCEALACRPPSHPC--------ANNTS 1191
Query: 5433 GCLQEQQLCDGRRDCMSGIDEQ--CDNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGY 5260
CL +LCDG+ DC G DE CD CS C + G CSC G
Sbjct: 1192 VCLSPDKLCDGKDDCGDGSDEGELCDQ----CSLNNGGCSHNCSVAPGEGIV-CSCPLGM 1246
Query: 5259 HLSPYDKKTCLRSPSCPK-ANCSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAE 5083
L P D TC C K CS C D+ +C C G++L + + CR D +
Sbjct: 1247 ELGP-DNHTCQIQSYCAKHLKCSQKC-DQNKFSVKCSCYEGWVLEPDGESCRSLDPFKPF 1304
Query: 5082 ILMVYGHRLKLFTIDGHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSN 4903
I+ H ++ + + L+ L N +ALD+ + +YWTDV D G +
Sbjct: 1305 IIFSNRHEIRRIDLHKGDYSVLVPGLRNTIALDFHLSQSALYWTDVVEDKIYRGKLLDNG 1364
Query: 4902 QPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDP 4723
++ V+ +G+AVDW+ NIY+ + N D I V + G LL G + P
Sbjct: 1365 ALTSFEVVIQYGLATPEGLAVDWIAGNIYWVESNLDQIEVAKLDGTLRTTLLAG-DIEHP 1423
Query: 4722 RAIVLDPLQALVFWTDWGAS-AHIGRMNMDGSNEQVILQDR-TIRWPNALAVDAPAQRLY 4549
RAI LDP ++FWTDW AS I +M G+ + I ++ + WPN L VD +R+
Sbjct: 1424 RAIALDPRDGILFWTDWDASLPRIEAASMSGAGRRTIHRETGSGGWPNGLTVDYLEKRIL 1483
Query: 4548 FGDAHRDYIASCNYDGSKRRMVLRGS--VRHIFALAVFEDYVYWSDWHNHTIERVHKITG 4375
+ DA D I S YDGS VLRG + H FA+ ++ VYW+DW +T+ + +K TG
Sbjct: 1484 WIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYGGEVYWTDWRTNTLAKANKWTG 1543
Query: 4374 TNRKVLIQDKQYRPMGFKIVHPSLQSMG----SLKTARHPCSQPARCD-NLCIPANTPDL 4210
N V +Q +P ++ HPS Q M R PCS + N + P L
Sbjct: 1544 HNVTV-VQRTNTQPFDLQVYHPSRQPMAPNPCEANGGRGPCSHLCLINYNRTVSCACPHL 1602
Query: 4209 -TTSSDNFTC 4183
+DN TC
Sbjct: 1603 MKLHNDNTTC 1612
Score = 337 bits (865), Expect = 2e-90
Identities = 451/1916 (23%), Positives = 686/1916 (35%), Gaps = 290/1916 (15%)
Frame = -1
Query: 5214 CPKAN--CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTI 5041
C AN C C+ R C CA G +L+E+ CR E ++Y R L +I
Sbjct: 2193 CAVANGGCQQLCLYRGGGQRACACAHG-MLAEDGASCR-----EYAGYLLYSERTILKSI 2246
Query: 5040 DGHAKATLLS---------NLTNGVALDYDVKS-------DLVYWTDVAHDGNKAGITSM 4909
+ L + ++ N +AL +D ++ + ++++D+ H GN I
Sbjct: 2247 HLSDERNLNAPVQPFEDPEHMKNVIALAFDYRAGTSPGTPNRIFFSDI-HFGNIQQINDD 2305
Query: 4908 SNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIA---VCDMR-GRFNR---IL 4750
+ T ++ ++ + ++G+A +Y+T I V R G F R I
Sbjct: 2306 GSGRTT--IVENVGS--VEGLAYHRGWDTLYWTSYTTSTITRHTVDQTRPGAFERETVIT 2361
Query: 4749 LKGTPLNDPRAIVLDPLQALVFWTDWGA-SAHIGRMNMDGSNEQVILQDRTIRWPNALAV 4573
+ G + PRA VLD Q L+FWT+W I R + G+N +++ + IR PN LA+
Sbjct: 2362 MSGD--DHPRAFVLDECQNLMFWTNWNELHPSIMRAALSGANVLTLIE-KDIRTPNGLAI 2418
Query: 4572 DAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIER 4393
D A++LYF DA D I C YDGS R ++L+ H F LAV+ ++++W+DW ++R
Sbjct: 2419 DHRAEKLYFSDATLDKIERCEYDGSHRYVILKSEPVHPFGLAVYGEHIFWTDWVRRAVQR 2478
Query: 4392 VHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCS-QPARCDNLCIPANTP 4216
+K G++ K+L D +PMG V S PC C +LC
Sbjct: 2479 ANKYVGSDMKLLRVDIPQQPMGIIAVANDTNSC-----ELSPCRINNGGCQDLC------ 2527
Query: 4215 DLTTSSDNFTCMCAQGFRSEGRSCVSECKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXX 4036
L T + C C G DF C + ++S R
Sbjct: 2528 -LLTHQGHVNCSCRGG----------RILQEDFTC----RAMNSSCRAQD---------- 2562
Query: 4035 GYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFEC 3856
+F C A +C+ S CDGV C DE+P++C + C
Sbjct: 2563 ----------------EFEC------ANGECISFSLTCDGVSHCKDKSDEKPSYCNSRRC 2600
Query: 3855 TEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCKPDFFACFNGTAI------- 3697
+ +C + + C+ C+ DC DGSDE+ C T+C F C +G+ I
Sbjct: 2601 KKTFRQCNNGR-CVSNMLWCNGVDDCGDGSDEIPCNKTACGVGEFRCRDGSCIGNSSRCN 2659
Query: 3696 --------------------------------------SKCIPKEFYCDGEDDCPEGQDE 3631
S C + CDG +DC + DE
Sbjct: 2660 QFVDCEDASDEMNCSATDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDE 2719
Query: 3630 PDSCFGI--GECTHEQFQCTSGKCIPKRRQCDGTLDCRDGSDEKGCKKECA---IVCDN- 3469
DS G+ C F C SG+CIP CD DC +G DE C K C+ C N
Sbjct: 2720 RDSP-GVKRPRCPLNYFACPSGRCIPMSWTCDKEDDCENGEDETHCNKFCSEAQFECQNH 2778
Query: 3468 SCVHADDLCDGKKKCNDGSDE----DEEACVIKQLLEKENRKC--GGFACDGIVDCEDGS 3307
C+ LCDG C DGSDE + + C C + CDG DC DG+
Sbjct: 2779 RCISKQWLCDGSDDCGDGSDEAAHCEGKTCGPSSFSCPGTHVCVPERWLCDGDKDCADGA 2838
Query: 3306 DE---------KGCPDLEC----HLASNKSLICDGTIDCSSGKDEN-NC-HNNGESNFFQ 3172
DE C D E L K +CD DC+ G DE+ C + N F+
Sbjct: 2839 DESISAGCLYNSTCDDREFMCQNRLCIPKHFVCDHDRDCADGSDESPECEYPTCGPNEFR 2898
Query: 3171 CS---MQTIKEWQVCDGRWDCADGLDESPE--MCASRKARCFRIG-YCDDKKQCLDVSTA 3010
C+ + ++W+ CDG DC D DE+P+ C S + +C + +C+
Sbjct: 2899 CANGRCLSSRQWE-CDGENDCHDHSDEAPKNPHCTSPEHKCNASSQFLCSSGRCV-AEAL 2956
Query: 3009 LCDGIRDCFDGSDENPIHCKDMCKGKYRCTNGRCID------VSARXXXXXXXXXXXXXX 2848
LC+G DC DGSDE H + K + C D V R
Sbjct: 2957 LCNGQDDCGDGSDERGCHVNECLSRKLSGCSQDCEDLKIGFKVHCRCRPGFRLKDDGRTC 3016
Query: 2847 XXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLH 2668
EC C+Q C + + + +C C GYA D + C+ ++ E F+ NR +
Sbjct: 3017 ADVDECSTTFPCSQLC-INTHGSYKCLCVEGYAPRGGDPHSCKAVT-DEEPFLIFANRYY 3074
Query: 2667 L--MSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSD 2494
L ++L+ S ++L+ N + +DF Y R ++Y + IR
Sbjct: 3075 LRKLNLDGSNYTLLKQGLNNAV-----ALDFDY---RGQMIYWTDVTTQGSMIRRMH--- 3123
Query: 2493 GLIGSWGEEESTAGL-----ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTST 2329
L GS + GL + D++ N+Y+ + I V+K
Sbjct: 3124 -LNGSNVQVLHRTGLSNPDGLAVDWVGGNLYWCDKGRD----------TIEVSKLNGAYR 3172
Query: 2328 RTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVE 2149
L+ + +L VD ++WT I +DG +V+
Sbjct: 3173 TVLVSSGLREPRALVVDVQNGYLYWTDWGDHSLIGRIGMDG-----------SGRSIIVD 3221
Query: 2148 RNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFEL------GDTPVTMD 1987
I P + +D+ ER+YW D + IE S DG +R L T
Sbjct: 3222 TKITWPNGLTVDYVTERIYWADAREDYIEFASLDGSNRHVGPYARLRWDSRRSGRHGTQS 3281
Query: 1986 VLGG-------------------YIYLIT-----------RQGSIHRMHKFTGKTNKYVQ 1897
VLG +I+ +T SI+R HK TG +
Sbjct: 3282 VLGANFCSVSPASPPTVLSQDIPHIFALTLFEDYVYWTDWETKSINRAHKTTGANKTLL- 3340
Query: 1896 KIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLC-- 1723
I + + + V H + +PC+ + + +C+ KC C
Sbjct: 3341 -ISTLHRPMDLHVFHALRQP----DVPNHPCKVNNGGCSNLCLLSPGGG----HKCACPT 3391
Query: 1722 -----GPGRF---------FEVSTKKCMQLREKDQEASQCGDY----------------- 1636
G GR F KC+ K CGD+
Sbjct: 3392 NFYLGGDGRTCVSNCTASQFVCKNDKCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQF 3451
Query: 1635 -----FCYNNAG-CSPQKTC------------VCPPGFYGRQCEINEC---------SET 1537
C N A C C VC P + + N C +
Sbjct: 3452 QCSTGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQF-KCTNTNRCIPGIFRCNGQDN 3510
Query: 1536 CWNGE--------TCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCP 1381
C +GE TCA +F + C P + N C +C + C
Sbjct: 3511 CGDGEDERDCPEVTCAPNQFQCSITKRC-IPRVWVCD--RDNDCVDGSDEPANCTQMTCG 3567
Query: 1380 KDEPHCRSYSFC---------ECDKGWTGPHCRHKADAKVCYGH---CFSGGACDGEGPL 1237
DE C+ C E D G + + D + C + C + G
Sbjct: 3568 VDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCKNNRCVPGRWQC 3627
Query: 1236 NLRCSCGDGLTGNRCQ---------NCVGHECLNGGF-------CSYANSNRS-LPHC-- 1114
+ CGD C +C C+ G + C+ + + P C
Sbjct: 3628 DYDNDCGDNSDEESCTPRPCSESEFSCANGRCIAGRWKCDGDHDCADGSDEKDCTPRCDM 3687
Query: 1113 ---ICPSGF---------TGDHCEEYLCKDACPFGSKCTYDITKPMDPITCS---CEQNA 979
C SG C + ++AC G + T P+D C+ C+ A
Sbjct: 3688 DQFQCKSGHCIPLRWRCDADADCMDGSDEEACGTGGE-----TCPLDEFQCNNTLCKPLA 3742
Query: 978 --AAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCK----CLPRFAGPRCDVPVQCDDY 817
DC + P C R P P +CK CL + G +CD C D
Sbjct: 3743 WKCDGEDDCGDNSDENPEEC---TRFQCPPNRPFRCKNDRVCL--WIGRQCDGTDNCGD- 3796
Query: 816 CTNNSKCTITNGTHFECDCKPGF---------KGLRCEQETKCSECSNEAKCIKKPSGTV 664
T+ C + C K F LRC C + S+E C P
Sbjct: 3797 GTDEEDCEPPTAQNPHCKDKKEFLCRNQRCLSSSLRCNMFDDCGDGSDEEDCSIDP---- 3852
Query: 663 ICQCPQGLGGEYCEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSSN 484
K+T+ + + C + C++ + +A C C PGF +
Sbjct: 3853 --------------KLTSCATNASMCGDEARCVRTEKAA-----YCACRPGFH-TVPGQP 3892
Query: 483 ACE--NFCLHDGNCTL---DEYFEPQCECYQAFI--GDRCQYRIHQHAVIFSDDDS 337
C+ N CL G C+ + C C + F+ + C+ ++ V++ DD+
Sbjct: 3893 GCQDINECLRFGTCSQLCNNTKGGHLCSCARNFMKTHNTCKAEGSEYQVLYIADDN 3948
Score = 331 bits (848), Expect = 2e-88
Identities = 317/1276 (24%), Positives = 503/1276 (38%), Gaps = 121/1276 (9%)
Frame = -1
Query: 5259 HLSPYDKKTCLRSPSCPK------ANCSHFCI-DRRDVGHQCFCAPGYILSENQKDCRRN 5101
H+ ++ +RS +C CS C+ C C G+ L + K C++
Sbjct: 464 HIYHQRRQPRVRSHACENDQYGKPGGCSDICLLANSHKARTCRCRSGFSLGSDGKSCKKP 523
Query: 5100 DTIEAEILMVYGHRLK--LFTIDGHAKAT-----LLSNLTNGVALDYDVKSDLVYWTDVA 4942
E E+ +VYG + +D AK + NL N ALD+ ++ +Y+ D
Sbjct: 524 ---EHELFLVYGKGRPGIIRGMDMGAKVPDEHMIPIENLMNPRALDFHAETGFIYFADTT 580
Query: 4941 H--------DGN------KAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTD- 4807
DG K G + P + + ++G+AVDW+G N+Y+TD
Sbjct: 581 SYLIGRQKIDGTERETILKDGKGVRGSPPGIPYTLTGI--HNVEGVAVDWMGDNLYWTDD 638
Query: 4806 --RNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDW------GASAHIG 4651
+ ++A + + + L++G + PRAIV+DPL ++WTDW +
Sbjct: 639 GPKKTISVARLEKAAQTRKTLIEGK-MTHPRAIVVDPLNGWMYWTDWEEDPKDSRRGRLE 697
Query: 4650 RMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRG- 4474
R MDGS+ + + +T+ WPN L++D PA RLY+ DA D I + +G+ R++V G
Sbjct: 698 RAWMDGSHRDIFVTSKTVLWPNGLSLDIPAGRLYWVDAFYDRIETILLNGTDRKIVYEGP 757
Query: 4473 SVRHIFALAVFEDYVYWSDWHNHTIERVHK-ITGTNRKVLIQDKQYRPM-GFKIVHPSLQ 4300
+ H F L +Y++W+++ + ++ R+ + + G V + + P+ ++ Q
Sbjct: 758 ELNHAFGLCHHGNYLFWTEYRSGSVYRLERGVAGAQPTVTLLRSERPPIFEIRMYDAQQQ 817
Query: 4299 SMGSLKTARHPCSQPARCDNLCIPANTPDLTTSSDNFTCMCAQGFRSEGRSCVS------ 4138
+G+ K C +LC+ T S C Q ++G +C++
Sbjct: 818 QVGTNKCR----VNNGGCSSLCL------ATPGSRQCACAEDQVLDADGVTCLANPSYVP 867
Query: 4137 --ECKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTA 3964
+C+P +F C +CI W+
Sbjct: 868 PPQCQPGEFACANN-RCIQERWK------------------------------------- 889
Query: 3963 QNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEK 3784
CDG DC DE PA C C +FKC + +CIP +CD +
Sbjct: 890 -------------CDGDNDCLDNSDEAPALCHQHTCPSDRFKC-ENNRCIPNRWLCDGDN 935
Query: 3783 DCDDGSDELN--CEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGI 3610
DC + DE N C +C P+ F+C +G +CIP + CD +DDC + DE SC
Sbjct: 936 DCGNSEDESNATCSARTCPPNQFSCASG----RCIPISWTCDLDDDCGDRSDESASCAYP 991
Query: 3609 GECTHEQFQCTSGKCIPKRRQCDGTLDCRDGSDEKGCKKECAIVC-DNS----------- 3466
QF C +G+CI +CD DC DGSDEK C + C DNS
Sbjct: 992 TCFPLTQFTCNNGRCININWRCDNEKDCGDGSDEKTCPEPADNDCGDNSDEAGCSHSCSS 1051
Query: 3465 ---------CVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKENRKCGG----------- 3346
C+ CDG C D SDE C + R GG
Sbjct: 1052 TQFKCNSGRCIPEHWTCDGDNDCGDYSDETHANCT-----NQATRPPGGCHSDEFQCRLD 1106
Query: 3345 -------FACDGIVDCEDGSDEKGCPDL-------------ECHLASNKSLICDGTIDCS 3226
+ CDG DC D SDEKGC + + +K+ +CDG DC
Sbjct: 1107 GLCIPLRWRCDGDTDCMDSSDEKGCEGVTHVCDPNVKFGCKDSARCISKAWVCDGDSDCE 1166
Query: 3225 SGKDENNCHNNG-ESNFFQCSMQT---IKEWQVCDGRWDCADGLDESP--EMCASRKARC 3064
DE NC C+ T + ++CDG+ DC DG DE + C+ C
Sbjct: 1167 DNSDEENCEALACRPPSHPCANNTSVCLSPDKLCDGKDDCGDGSDEGELCDQCSLNNGGC 1226
Query: 3063 FRIGYCDDKKQCLDVSTALCDGI-RDCFDGSDENPIHCKDMCKGKYRCTNGRCIDVSARX 2887
+ S A +GI C G + P N C
Sbjct: 1227 SH-----------NCSVAPGEGIVCSCPLGMELGP-------------DNHTC------- 1255
Query: 2886 XXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSK 2707
+ C C+QKC + +C C G+ + D C L
Sbjct: 1256 -------------QIQSYCAKHLKCSQKCDQN-KFSVKCSCYEGWV-LEPDGESCRSLDP 1300
Query: 2706 SAEMFI-TNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGN 2530
I +N + + + L SVL P N I +DF + +Y +
Sbjct: 1301 FKPFIIFSNRHEIRRIDLHKGDYSVLVPGLR---NTI--ALDFH---LSQSALYWTDVVE 1352
Query: 2529 SRVDIRSKKWSDGLIGSWGEEESTAGLIT-----YDFMHNNVYFTESSEQNRGVLFDRQA 2365
++ R K +G + S+ E GL T D++ N+Y+ ES+
Sbjct: 1353 DKI-YRGKLLDNGALTSF-EVVIQYGLATPEGLAVDWIAGNIYWVESNLD---------- 1400
Query: 2364 NIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTT-SAPVPRILSANLDG---KPI 2197
I VAK T TL+ ++A+DP ++FWT A +PRI +A++ G + I
Sbjct: 1401 QIEVAKLDGTLRTTLLAGDIEHPRAIALDPRDGILFWTDWDASLPRIEAASMSGAGRRTI 1460
Query: 2196 AQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTV-RK 2020
+ +G P+ + +D+ +R+ WID I + +DG V R
Sbjct: 1461 HRETGSGGWPN------------GLTVDYLEKRILWIDARSDAIYSARYDGSGHMEVLRG 1508
Query: 2019 FELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAK 1843
E P + + GG +Y R ++ + +K+TG VQ R + ++V HP++
Sbjct: 1509 HEFLSHPFAVTLYGGEVYWTDWRTNTLAKANKWTGHNVTVVQ--RTNTQPFDLQVYHPSR 1566
Query: 1842 HTVSHITHQKNPCQSD 1795
++ NPC+++
Sbjct: 1567 QPMA-----PNPCEAN 1577
Score = 204 bits (519), Expect = 2e-50
Identities = 149/520 (28%), Positives = 241/520 (45%), Gaps = 28/520 (5%)
Frame = -1
Query: 5619 RQCKPNEWMC-DSGQCIDSGRLCDASVDCVDGSDEWVEICSLSEPPRRGCPSG-WSCLLT 5446
+ C P ++ C D CI G CD DC DGSDE EIC S+ R CP SCL
Sbjct: 26 KTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQR--CPPNEHSCL-- 81
Query: 5445 NGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSSTRNSCDQTWNCQRHA----GFESC 5278
GT C+ +LC+G +DCM G DE +C R +C + CQ H +C
Sbjct: 82 -GTELCVPMSRLCNGIQDCMDGSDEGA-----HCRELRVNCSRM-GCQHHCVPTPSGPTC 134
Query: 5277 SCDDGYHLSPYDKKTCLRSPSCPK-ANCSHFCIDRRDVGHQCFCAPGYILSENQKDCR-R 5104
C++ + L D KTC C CS C + D C C GY+L + + C+ +
Sbjct: 135 YCNNSFQLQA-DGKTCKDFDECSVYGTCSQLCTNT-DGSFTCGCVEGYLLQPDNRSCKAK 192
Query: 5103 NDTIEAEILMVYGHRLKLFT--IDGHAKATLLSNLTNGV-ALDYDVKSDLVYWTDVAHDG 4933
N+ ++ +++ + + + G +T+ T A+D+ ++ V W V
Sbjct: 193 NEPVDRPPVLLIANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWVHVGDSA 252
Query: 4932 NK-----AGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRG 4768
+ A + S+ + + + SL ++ +A+DWL N Y+ D D I VC+ G
Sbjct: 253 AQTQLKCARMPSLKGFVDEHTINISLSLHHVEQMAIDWLTGNFYFVDDIDDRIFVCNRNG 312
Query: 4767 RFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWP 4588
+ L L +P+ I LDP VF+TD+G + R +MDG N + L D I +P
Sbjct: 313 D-TCVTLLDLELYNPKGIALDPAMGKVFFTDYGQIPKVERCDMDGQN-RTKLVDSKIVFP 370
Query: 4587 NALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRG-SVRHIFALAVFEDYVYWSDWH 4411
+ + +D ++ +Y+ DA+ DYI +Y+G R+ +++G + H++ L VFE+Y+Y ++
Sbjct: 371 HGITLDLVSRLVYWADAYLDYIEVVDYEGKGRQTIIQGILIEHLYGLTVFENYLYATNSD 430
Query: 4410 NHTIERVHKITGTNR----KVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPC-----SQ 4258
N ++ + NR + + + + I H Q + H C +
Sbjct: 431 NANTQQKTSVIRVNRFNSTEYQVVTRVDKGGALHIYHQRRQP----RVRSHACENDQYGK 486
Query: 4257 PARCDNLCIPANTPDLTTSSDNFTCMCAQGFR--SEGRSC 4144
P C ++C+ AN S TC C GF S+G+SC
Sbjct: 487 PGGCSDICLLAN------SHKARTCRCRSGFSLGSDGKSC 520
Score = 167 bits (423), Expect = 3e-39
Identities = 104/287 (36%), Positives = 138/287 (47%), Gaps = 20/287 (6%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADES-NC---TCNE-NEFR 6409
+DE CS R C P F+C +G CIP C+ +DC + +DES +C TC +F
Sbjct: 941 EDESNATCSARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQFT 1000
Query: 6408 CQSGACIPSKARCNHMQDCNDASDEIGCP---FRNC-SALNEFGMTGLINCATT------ 6259
C +G CI RC++ +DC D SDE CP +C +E G + +C++T
Sbjct: 1001 CNNGRCININWRCDNEKDCGDGSDEKTCPEPADNDCGDNSDEAGCSH--SCSSTQFKCNS 1058
Query: 6258 SQCIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKH 6079
+CI W CDG NDC D SDE + T + P C + +F C C+P
Sbjct: 1059 GRCIPEHWTCDGDNDCGDYSDE----THANCTNQATRPPGGCHS-DEFQCRLDGLCIPLR 1113
Query: 6078 WQCDGQPDCADGSDEKNCD--AKKC-TSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQ 5908
W+CDG DC D SDEK C+ C + +F C+ S +CI CDG DC D DE
Sbjct: 1114 WRCDGDTDCMDSSDEKGCEGVTHVCDPNVKFGCKDSARCISKAWVCDGDSDCEDNSDEEN 1173
Query: 5907 CETECDSKGGNATFRCTNHR--CIPMAWRCDGTDDCMDNAKSLGSDE 5773
CE + C N+ C+ CDG DDC D GSDE
Sbjct: 1174 CEALACRPPSHP---CANNTSVCLSPDKLCDGKDDCGD-----GSDE 1212
Score = 155 bits (393), Expect = 1e-35
Identities = 110/387 (28%), Positives = 180/387 (46%), Gaps = 15/387 (3%)
Frame = -1
Query: 5259 HLSPYDKKTCLRSP-----SCPKANCSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDT 5095
H+ YD+ L S +CS C+ + C C GY L Q+ C +
Sbjct: 1866 HMKVYDESIQLEHEGTNPCSVNNGDCSQLCLPTSETTRSCMCTAGYSLRSGQQAC---EG 1922
Query: 5094 IEAEILMVYGHRLKLFTIDGHAKATLL---SNLTNGVALDYDVKSDLVYWTDVAHDGNKA 4924
+ + +L ++ +D + K+ L S + V +D+ ++D +YW D+
Sbjct: 1923 VGSFLLYSVHEGIRGIPLDPNDKSDALVPVSGTSLAVGIDFHAENDTIYWVDM------- 1975
Query: 4923 GITSMSNQPNTYRVINSLPTKGI---DGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRI 4753
G++++S + T GI +GIAVDW+ NIY+TD+ D I V + G F +
Sbjct: 1976 GLSTISRAKRDQTWREDVVTNGIGRVEGIAVDWIAGNIYWTDQGFDVIEVARLNGSFRYV 2035
Query: 4752 LLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAV 4573
++ L+ PRAI + P + +FWT+WG I R +DG+ E+V+L + +I WPN ++V
Sbjct: 2036 VI-SQGLDKPRAITVHPEKGYLFWTEWGHYPRIERSRLDGT-ERVVLVNVSISWPNGISV 2093
Query: 4572 DAPAQRLYFGDAHRDYIASCNYD-GSKRRMVLRGSVRHIFALAVFEDYVYWSD--WHNHT 4402
D +LY+ DA D I + + G R +VL + +F+++VFED++YWSD N +
Sbjct: 2094 DYQGGKLYWCDARMDKIERIDLETGENREVVLSSNNMDMFSVSVFEDFIYWSDRTHANGS 2153
Query: 4401 IERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDNLCIPAN 4222
I+R K T+ L + K+ + Q ++ + C LC
Sbjct: 2154 IKRGCKDNATDSVPLRTGIGVQLKDIKVFNRDRQKGTNVCAVAN-----GGCQQLC---- 2204
Query: 4221 TPDLTTSSDNFTCMCAQGFRSE-GRSC 4144
L C CA G +E G SC
Sbjct: 2205 ---LYRGGGQRACACAHGMLAEDGASC 2228
Score = 129 bits (325), Expect = 7e-28
Identities = 97/365 (26%), Positives = 166/365 (44%), Gaps = 13/365 (3%)
Frame = -1
Query: 5199 CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAK-- 5026
CSH C+ + C C L + C E + ++Y ++++ +D A
Sbjct: 1583 CSHLCLINYNRTVSCACPHLMKLHNDNTTC-----YEFKKFLLYARQMEIRGVDLDAPYY 1637
Query: 5025 ----ATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKG 4858
+ + ++ N LDYD + VYW+DV K + + + S
Sbjct: 1638 NYIISFTVPDIDNVTVLDYDAREQRVYWSDVRTQAIKRAFINGTG----VETVVSADLPN 1693
Query: 4857 IDGIAVDWLGRNIYYT--DRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVF 4684
G+AVDW+ RN+++T D N I V + G F +++G L P +V+ PL+ ++
Sbjct: 1694 AHGLAVDWVSRNLFWTSYDTNKKQINVARLDGSFKNAVVQG--LEQPHGLVVHPLRGKLY 1751
Query: 4683 WTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYD 4504
WTD +I +NMDGSN ++ + + P LA+D P +LY+ + I CN D
Sbjct: 1752 WTD---GDNISMVNMDGSNRTLLFSGQ--KGPVGLAIDFPESKLYWISSGNHTINRCNLD 1806
Query: 4503 GSKRRMV--LRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPM 4330
GS+ ++ +R + ALA+ D ++W+D + + +K G+ V++++ M
Sbjct: 1807 GSELEVIDTMRSQLGKATALAIMGDKLWWADQVSEKMGTCNKADGSG-SVVLRNSTTLVM 1865
Query: 4329 GFKIVHPSLQSMGSLKTARHPCS-QPARCDNLCIPANTPDLTTSSDNFTCMCAQGF--RS 4159
K+ S+Q +PCS C LC+P TS +CMC G+ RS
Sbjct: 1866 HMKVYDESIQLE---HEGTNPCSVNNGDCSQLCLP-------TSETTRSCMCTAGYSLRS 1915
Query: 4158 EGRSC 4144
++C
Sbjct: 1916 GQQAC 1920
Score = 114 bits (284), Expect = 4e-23
Identities = 112/468 (23%), Positives = 182/468 (37%), Gaps = 21/468 (4%)
Frame = -1
Query: 3153 KEWQVCDGRWDCADGLDESPEMCASRKA-RCFRIGY-CDDKKQCLDVSTALCDGIRDCFD 2980
K W+ CDG DC DG DE+PE+C KA RC + C + C+ +S LC+GI+DC D
Sbjct: 44 KGWR-CDGERDCPDGSDEAPEICPQSKAQRCPPNEHSCLGTELCVPMS-RLCNGIQDCMD 101
Query: 2979 GSDENPIHCKDMCKGKYRCTNGRC--------IDVSARXXXXXXXXXXXXXXXXGAECHH 2824
GSDE HC+++ + C+ C + EC
Sbjct: 102 GSDEG-AHCREL---RVNCSRMGCQHHCVPTPSGPTCYCNNSFQLQADGKTCKDFDECSV 157
Query: 2823 FGVCAQKCWMAFNHTARCHCAPGYARTKNDENEC----EPLSKSAEMFITNGNRLHLMSL 2656
+G C+Q C + + C C GY + D C EP+ + + I N + L
Sbjct: 158 YGTCSQLCTNT-DGSFTCGCVEGYL-LQPDNRSCKAKNEPVDRPPVLLIANSQNILATYL 215
Query: 2655 ENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSW 2476
+QVS + P + +DF Y T VG ++ ++ + L G
Sbjct: 216 SGAQVSTITPTSTRQTT----AMDFSY-ANETVCWVHVGDSAAQTQLKCAR-MPSLKGFV 269
Query: 2475 GEEESTAGL-------ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLI 2317
E L + D++ N YF + D I+V + TL+
Sbjct: 270 DEHTINISLSLHHVEQMAIDWLTGNFYFVD----------DIDDRIFVCNRNGDTCVTLL 319
Query: 2316 VNSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIF 2137
+A+DP +F+T +P++ ++DG Q LV+ I
Sbjct: 320 DLELYNPKGIALDPAMGKVFFTDYGQIPKVERCDMDG-----------QNRTKLVDSKIV 368
Query: 2136 EPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT 1957
P + LD + +YW D IE V ++G+ R+T+ + L + + V Y+Y
Sbjct: 369 FPHGITLDLVSRLVYWADAYLDYIEVVDYEGKGRQTIIQGILIEHLYGLTVFENYLYATN 428
Query: 1956 RQGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQK 1813
+ + + N++ +V R+ K HI HQ+
Sbjct: 429 SDNANTQQKTSVIRVNRFNSTEYQVVTRVD-------KGGALHIYHQR 469
Score = 111 bits (277), Expect = 3e-22
Identities = 202/903 (22%), Positives = 332/903 (36%), Gaps = 90/903 (9%)
Frame = -1
Query: 2820 GVCAQKCWMAFNHTAR-CHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQ 2644
G C+ C +A +H AR C C G++ +D C+ + G + ++
Sbjct: 488 GGCSDICLLANSHKARTCRCRSGFS-LGSDGKSCKKPEHELFLVYGKGRPGIIRGMDMGA 546
Query: 2643 VSVLRPVFNIKMNLIPGGIDF----GYDVFRTTLMYTVGIGNSRVDIRSK----KWSDGL 2488
+ I+ + P +DF G+ F T Y IG ++D + K G+
Sbjct: 547 KVPDEHMIPIENLMNPRALDFHAETGFIYFADTTSYL--IGRQKIDGTERETILKDGKGV 604
Query: 2487 IGSW-GEEESTAGL-----ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTST- 2329
GS G + G+ + D+M +N+Y+T+ + I VA+ + +
Sbjct: 605 RGSPPGIPYTLTGIHNVEGVAVDWMGDNLYWTDDGPKK---------TISVARLEKAAQT 655
Query: 2328 -RTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALV 2152
+TLI ++ VDP+ ++WT P+ + G+ + + + GS +
Sbjct: 656 RKTLIEGKMTHPRAIVVDPLNGWMYWTDWEEDPK---DSRRGR-LERAWMDGSHRDIFVT 711
Query: 2151 ERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGY 1972
+ + P + LD RLYW+D IET+ +G DR+ V + + + G Y
Sbjct: 712 SKTVLWPNGLSLDIPAGRLYWVDAFYDRIETILLNGTDRKIVYEGPELNHAFGLCHHGNY 771
Query: 1971 IYLIT-RQGSIHRMHKFTGKTNKYVQKIREVSPRI-QIRVAHPAKHTV-SHITHQKNPCQ 1801
++ R GS++R+ + V +R P I +IR+ + V ++ N
Sbjct: 772 LFWTEYRSGSVYRLERGVAGAQPTVTLLRSERPPIFEIRMYDAQQQQVGTNKCRVNNGGC 831
Query: 1800 SDYC---PSNTVCVPDQDK-----------NGILIPKCLCGPGRFFEVSTKKCMQLREKD 1663
S C P + C +D+ N +P C PG F + +C+Q R K
Sbjct: 832 SSLCLATPGSRQCACAEDQVLDADGVTCLANPSYVPPPQCQPGE-FACANNRCIQERWKC 890
Query: 1662 QEASQCGDYFCYNNAGCSPQ--KTCVCPPGFYGRQCEINECSETCW---NGETCAVQEFG 1498
GD C +N+ +P CP + +CE N C W C E
Sbjct: 891 D-----GDNDCLDNSDEAPALCHQHTCPSDRF--KCENNRCIPNRWLCDGDNDCGNSE-- 941
Query: 1497 STTNVVCH---CPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSYSFCECDKGW 1327
+N C CP N Q SCA+ C + + C D+ +C
Sbjct: 942 DESNATCSARTCPPN--QFSCASGRCIPI--------SWTCDLDD---------DCGD-- 980
Query: 1326 TGPHCRHKADAKVCYGHCF-------SGGACDGEGPLNLRC----SCGDGLTGNRCQNCV 1180
R A Y CF + G C +N RC CGDG C
Sbjct: 981 -----RSDESASCAYPTCFPLTQFTCNNGRCIN---INWRCDNEKDCGDGSDEKTCPEPA 1032
Query: 1179 GHEC---LNGGFCSYA--------NSNRSLP-HCICP-SGFTGDHCEEYLCKDACPFGSK 1039
++C + CS++ NS R +P H C GD+ +E +
Sbjct: 1033 DNDCGDNSDEAGCSHSCSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDE--------THAN 1084
Query: 1038 CTYDITKPMDPITCSCEQNAAAHNTDCSPICQKQPNW-CHNGGRCLDTPGYPGKCKCLPR 862
CT T+P P C ++ + C P+ W C C+D+ G C+ +
Sbjct: 1085 CTNQATRP--PGGCHSDEFQCRLDGLCIPL-----RWRCDGDTDCMDSSDEKG-CEGVTH 1136
Query: 861 FAGPRCDVPVQCDDYCTNNSKCTITNGTHFECDCKPGFKGLRCEQETKCSECSNEAKCIK 682
P +V C D SK + +G + DC+ CE C S+
Sbjct: 1137 VCDP--NVKFGCKDSARCISKAWVCDG---DSDCEDNSDEENCE-ALACRPPSHPC---- 1186
Query: 681 KPSGTVICQCPQGL--GGEYC--EKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSP 514
+ T +C P L G + C C Q NGG S C +P
Sbjct: 1187 -ANNTSVCLSPDKLCDGKDDCGDGSDEGELCDQCSLNNGG-----------CSHNCSVAP 1234
Query: 513 GFKGLLCS----------SNAC--ENFCLHDGNCTL---DEYFEPQCECYQAFI----GD 391
G +G++CS ++ C +++C C+ F +C CY+ ++ G+
Sbjct: 1235 G-EGIVCSCPLGMELGPDNHTCQIQSYCAKHLKCSQKCDQNKFSVKCSCYEGWVLEPDGE 1293
Query: 390 RCQ 382
C+
Sbjct: 1294 SCR 1296
Score = 109 bits (273), Expect = 8e-22
Identities = 94/387 (24%), Positives = 131/387 (33%), Gaps = 46/387 (11%)
Frame = -1
Query: 1173 ECLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCS 994
+C NGG C + N+ R P C C +TGD CE C +
Sbjct: 4275 QCFNGGSC-FLNARRQ-PKCRCQPRYTGDKCELDQCWE---------------------- 4310
Query: 993 CEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYC 814
+CHNGG C +P C+C F GPRC V C YC
Sbjct: 4311 ---------------------YCHNGGTCAASPSGMPTCRCPTGFTGPRCTQQV-CAGYC 4348
Query: 813 TNNSKCTITNGTHFECDCKPGFKGLRCEQET----------------------------- 721
NNS CT+ G +C C PGF G RC+
Sbjct: 4349 ANNSTCTVNQGNQPQCRCLPGFLGDRCQYREYSPQPQRRKRGAGTQRGSSRGWKPSADEP 4408
Query: 720 ----------------KCSE-CSNEAKCIKKPSGTVICQCPQGLGGEYCEKITATSCHQL 592
+CS C N C G+ C+C G CE + C Q
Sbjct: 4409 SPGLWVLPPTLAHLPGQCSGFCENFGTCQMAADGSRQCRCTVYFEGTRCEVNKCSRCLQ- 4467
Query: 591 ECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCLHDGNCTLDEYFEPQCEC 412
G C+ + + TC C+ G C + C + C + G+CT++ P+C+C
Sbjct: 4468 -----GACVVNKQTGD---VTCNCTDGRVAPSCLT--CIDHCSNGGSCTMNSKMMPECQC 4517
Query: 411 YQAFIGDRCQYRIHQHAVIFSDDDSGWIKSFXXXXXXXXXXXXXXXIFANRSNRFAVFRQ 232
G RC+ + + S G + S + R +
Sbjct: 4518 PPHMTGPRCEEQ------VVSQQQPGHMTSILIPLLLLLLLLLVAGVVFWYKRRVRGAKG 4571
Query: 231 FRHNPLQNQGAPVDQFSNPAYLIDEGG 151
F+H + N GA + NP Y + EGG
Sbjct: 4572 FQHQRMTN-GAMNVEIGNPTYKMYEGG 4597
Score = 102 bits (254), Expect = 1e-19
Identities = 80/276 (28%), Positives = 107/276 (37%), Gaps = 11/276 (3%)
Frame = -1
Query: 1287 CYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQ--NCVGHECLNGGFCSYANSNRSLPHC 1114
C CF+GG+C +C C TG++C+ C + C NGG C A S +P C
Sbjct: 4272 CTLQCFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCWEY-CHNGGTC--AASPSGMPTC 4328
Query: 1113 ICPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCSCEQNAAAHNT---DCSPICQ 943
CP+GFTG C + +C C S T + + P C C + SP Q
Sbjct: 4329 RCPTGFTGPRCTQQVCAGYCANNS--TCTVNQGNQP-QCRCLPGFLGDRCQYREYSPQPQ 4385
Query: 942 KQPNWC------HNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSKCTITNG 781
++ G + PG P A +P QC +C N C +
Sbjct: 4386 RRKRGAGTQRGSSRGWKPSADEPSPGLWVLPPTLA----HLPGQCSGFCENFGTCQMAAD 4441
Query: 780 THFECDCKPGFKGLRCEQETKCSECSNEAKCIKKPSGTVICQCPQGLGGEYCEKITATSC 601
+C C F+G RCE KCS C A + K +G V C C G C +T
Sbjct: 4442 GSRQCRCTVYFEGTRCEVN-KCSRCLQGACVVNKQTGDVTCNCTDGRVAPSC--LTCID- 4497
Query: 600 HQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLC 493
C NGG C ++ P C C P G C
Sbjct: 4498 ---HCSNGGSC----TMNSKMMPECQCPPHMTGPRC 4526
Score = 97.8 bits (242), Expect = 3e-18
Identities = 66/249 (26%), Positives = 91/249 (36%), Gaps = 15/249 (6%)
Frame = -1
Query: 1083 CEEYLCKDACPFGSKCTYDITKPMDPITCSCEQNAAAHNTDCSPICQKQPN--------- 931
C+ C+ C + P P+ C+C N C P+ P
Sbjct: 4223 CDRKKCEWLC---------LLSPSGPV-CTCPNGKRLDNGTCVPVPSPTPPPDAPRPGTC 4272
Query: 930 --WCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSKCTITNGTHFECDCK 757
C NGG C KC+C PR+ G +C++ QC +YC N C + C C
Sbjct: 4273 TLQCFNGGSCFLNARRQPKCRCQPRYTGDKCELD-QCWEYCHNGGTCAASPSGMPTCRCP 4331
Query: 756 PGFKGLRCEQETKCSECSNEAKCIKKPSGTVICQCPQGLGGEYCEKITATSCHQLECKNG 577
GF G RC Q+ C+N + C C+C G G+ C+ + Q +
Sbjct: 4332 TGFTGPRCTQQVCAGYCANNSTCTVNQGNQPQCRCLPGFLGDRCQYREYSPQPQRRKRGA 4391
Query: 576 GYCLKPD----PSANRTSPTCLCSPGFKGLLCSSNACENFCLHDGNCTLDEYFEPQCECY 409
G PSA+ SP P L C FC + G C + QC C
Sbjct: 4392 GTQRGSSRGWKPSADEPSPGLWVLP--PTLAHLPGQCSGFCENFGTCQMAADGSRQCRCT 4449
Query: 408 QAFIGDRCQ 382
F G RC+
Sbjct: 4450 VYFEGTRCE 4458
Score = 87.8 bits (216), Expect = 3e-15
Identities = 43/113 (38%), Positives = 61/113 (53%), Gaps = 5/113 (4%)
Frame = -1
Query: 6162 GGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADGSDE-----KNCDAKKCTSFE 5998
G ++ AP++C K QFAC TC+ K W+CDG+ DC DGSDE A++C E
Sbjct: 19 GATMDAPKTCSPK-QFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNE 77
Query: 5997 FSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNATFRCTNHRCIP 5839
SC ++ C+P+ + C+G +DC DG DE C N + H C+P
Sbjct: 78 HSCLGTELCVPMSRLCNGIQDCMDGSDE---GAHCRELRVNCSRMGCQHHCVP 127
Score = 81.3 bits (199), Expect = 3e-13
Identities = 40/112 (35%), Positives = 53/112 (46%)
Frame = -1
Query: 711 ECSNEAKCIKKPSGTVICQCPQGLGGEYCEKITATSCHQLECKNGGYCLKPDPSANRTSP 532
+C N C C+C G+ CE C + C NGG C PS P
Sbjct: 4275 QCFNGGSCFLNARRQPKCRCQPRYTGDKCE---LDQCWEY-CHNGGTCAA-SPSG---MP 4326
Query: 531 TCLCSPGFKGLLCSSNACENFCLHDGNCTLDEYFEPQCECYQAFIGDRCQYR 376
TC C GF G C+ C +C ++ CT+++ +PQC C F+GDRCQYR
Sbjct: 4327 TCRCPTGFTGPRCTQQVCAGYCANNSTCTVNQGNQPQCRCLPGFLGDRCQYR 4378
Score = 68.9 bits (167), Expect = 2e-09
Identities = 55/184 (29%), Positives = 75/184 (39%), Gaps = 15/184 (8%)
Frame = -1
Query: 3858 CTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDEL-----NCEITSCKPDFFACFNGTAIS 3694
C+ QF C D+ CI CD E+DC DGSDE + C P+ +C GT +
Sbjct: 28 CSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEHSCL-GTEL- 85
Query: 3693 KCIPKEFYCDGEDDCPEGQDEPDSCFGIG------ECTHEQFQCTSGKCIPKRRQCDGTL 3532
C+P C+G DC +G DE C + C H SG C+ +
Sbjct: 86 -CVPMSRLCNGIQDCMDGSDEGAHCRELRVNCSRMGCQHHCVPTPSGPTC----YCNNSF 140
Query: 3531 DCRDGSDEKGCK--KECAI--VCDNSCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKE 3364
+ +D K CK EC++ C C + DG C CV LL+ +
Sbjct: 141 QLQ--ADGKTCKDFDECSVYGTCSQLCTNT----DGSFTC---------GCVEGYLLQPD 185
Query: 3363 NRKC 3352
NR C
Sbjct: 186 NRSC 189
Score = 63.9 bits (154), Expect = 5e-08
Identities = 75/303 (24%), Positives = 118/303 (38%), Gaps = 8/303 (2%)
Frame = -1
Query: 2820 GVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQV 2641
G C+Q C T C C GY+ ++ + CE + + G R + N +
Sbjct: 1889 GDCSQLCLPTSETTRSCMCTAGYS-LRSGQQACEGVGSFLLYSVHEGIRGIPLD-PNDKS 1946
Query: 2640 SVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEES 2461
L PV + + GIDF + +Y V +G S + R+K+ +W E+
Sbjct: 1947 DALVPVSGTSLAV---GIDFHAE---NDTIYWVDMGLSTIS-RAKRDQ-----TWREDVV 1994
Query: 2460 TAGL-----ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTI 2296
T G+ I D++ N+Y+T+ FD I VA+ + +I
Sbjct: 1995 TNGIGRVEGIAVDWIAGNIYWTDQG-------FDV---IEVARLNGSFRYVVISQGLDKP 2044
Query: 2295 NSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVL 2116
++ V P K +FWT PRI + LDG LV +I P + +
Sbjct: 2045 RAITVHPEKGYLFWTEWGHYPRIERSRLDG-----------TERVVLVNVSISWPNGISV 2093
Query: 2115 DFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITR---QGS 1945
D+ +LYW D IE + + + R V ++ V +IY R GS
Sbjct: 2094 DYQGGKLYWCDARMDKIERIDLETGENREVVLSSNNMDMFSVSVFEDFIYWSDRTHANGS 2153
Query: 1944 IHR 1936
I R
Sbjct: 2154 IKR 2156
Score = 61.6 bits (148), Expect = 2e-07
Identities = 44/157 (28%), Positives = 56/157 (35%), Gaps = 20/157 (12%)
Frame = -1
Query: 6270 CATTSQCIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAK-------TQFA 6112
C CI W+CDG DC DGSDE AP C + +
Sbjct: 35 CRDQITCISKGWRCDGERDCPDGSDE---------------APEICPQSKAQRCPPNEHS 79
Query: 6111 CLATRTCMPKHWQCDGQPDCADGSDE--------KNCDAKKCTSFEFSCESSKKCI---P 5965
CL T C+P C+G DC DGSDE NC C S C
Sbjct: 80 CLGTELCVPMSRLCNGIQDCMDGSDEGAHCRELRVNCSRMGCQHHCVPTPSGPTCYCNNS 139
Query: 5964 LEQKCDGR--RDCPDGEDEHQCETECDSKGGNATFRC 5860
+ + DG+ +D + C C + G+ T C
Sbjct: 140 FQLQADGKTCKDFDECSVYGTCSQLCTNTDGSFTCGC 176
Score = 58.2 bits (139), Expect = 3e-06
Identities = 49/192 (25%), Positives = 69/192 (35%), Gaps = 21/192 (10%)
Frame = -1
Query: 4008 PFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFE---CTEAQFK 3838
P C QF C C+ CDG +DC G DE P C + C +
Sbjct: 25 PKTCSPKQFAC-----RDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEHS 79
Query: 3837 CGDKKKCIPLTSVCDKEKDCDDGSDE--------LNCEITSCKPDFFACFNGTAISKCIP 3682
C + C+P++ +C+ +DC DGSDE +NC C+ C+P
Sbjct: 80 CLGTELCVPMSRLCNGIQDCMDGSDEGAHCRELRVNCSRMGCQ------------HHCVP 127
Query: 3681 ----KEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQCDG--TLDCRD 3520
YC+ Q + +C EC+ G C DG T C +
Sbjct: 128 TPSGPTCYCNNSFQL---QADGKTCKDFDECS------VYGTCSQLCTNTDGSFTCGCVE 178
Query: 3519 G----SDEKGCK 3496
G D + CK
Sbjct: 179 GYLLQPDNRSCK 190
Score = 58.2 bits (139), Expect = 3e-06
Identities = 50/196 (25%), Positives = 69/196 (34%), Gaps = 3/196 (1%)
Frame = -1
Query: 5913 HQCETECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVP 5734
HQ C +GG R + + C N+ DE +CA G
Sbjct: 2531 HQGHVNCSCRGG---------RILQEDFTCRAM-----NSSCRAQDEFECANGE------ 2570
Query: 5733 SRCADETCVVACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLC 5554
C ++ CDG+ C D DEK R+CK C++G+C+ + C
Sbjct: 2571 -----------CISFSLTCDGVSHCKDKSDEKPSYCNSRRCKKTFRQCNNGRCVSNMLWC 2619
Query: 5553 DASVDCVDGSDEW---VEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMS 5383
+ DC DGSDE C + E C G C+ C+ DC
Sbjct: 2620 NGVDDCGDGSDEIPCNKTACGVGE---FRCRDG----------SCIGNSSRCNQFVDCED 2666
Query: 5382 GIDEQCDNPQGNCSST 5335
DE NCS+T
Sbjct: 2667 ASDEM------NCSAT 2676
Score = 55.1 bits (131), Expect = 2e-05
Identities = 53/214 (24%), Positives = 75/214 (34%), Gaps = 38/214 (17%)
Frame = -1
Query: 1794 YCPSNTVCVPDQDKNGILIPKCLCGPG------RFFEVSTKKCMQLREKDQEAS------ 1651
YC +N+ C +Q P+C C PG ++ E S + + R +
Sbjct: 4347 YCANNSTCTVNQGNQ----PQCRCLPGFLGDRCQYREYSPQPQRRKRGAGTQRGSSRGWK 4402
Query: 1650 ----------------------QCGDYFCYNNAGCSP----QKTCVCPPGFYGRQCEINE 1549
QC FC N C + C C F G +CE+N+
Sbjct: 4403 PSADEPSPGLWVLPPTLAHLPGQCSG-FCENFGTCQMAADGSRQCRCTVYFEGTRCEVNK 4461
Query: 1548 CSETCWNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEP 1369
CS C G C V + T +V C+C SC T C C GSC
Sbjct: 4462 CSR-CLQG-ACVVNK--QTGDVTCNCTDGRVAPSCLT--CIDHCSNGGSCTM-------- 4507
Query: 1368 HCRSYSFCECDKGWTGPHCRHKADAKVCYGHCFS 1267
+ + C+C TGP C + ++ GH S
Sbjct: 4508 NSKMMPECQCPPHMTGPRCEEQVVSQQQPGHMTS 4541
Score = 54.7 bits (130), Expect = 3e-05
Identities = 77/393 (19%), Positives = 142/393 (35%), Gaps = 14/393 (3%)
Frame = -1
Query: 2820 GVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQV 2641
G C+ C + +N T C C P + ND C K L+ +E V
Sbjct: 1581 GPCSHLCLINYNRTVSCAC-PHLMKLHNDNTTCYEFKKFL---------LYARQMEIRGV 1630
Query: 2640 SVLRPVFNIKMNLIPGGID----FGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWG 2473
+ P +N ++ ID YD + ++ D+R++ I G
Sbjct: 1631 DLDAPYYNYIISFTVPDIDNVTVLDYDAREQRVYWS--------DVRTQAIKRAFINGTG 1682
Query: 2472 EEE------STAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVN 2311
E A + D++ N+++T S + N+ +Q N+ D S + +V
Sbjct: 1683 VETVVSADLPNAHGLAVDWVSRNLFWT-SYDTNK-----KQINV---ARLDGSFKNAVVQ 1733
Query: 2310 STGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEP 2131
+ L V P++ ++WT + + N+DG ++ L+ P
Sbjct: 1734 GLEQPHGLVVHPLRGKLYWTDGDNISMV---NMDGS------------NRTLLFSGQKGP 1778
Query: 2130 TSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTV--RKFELGDTPVTMDVLGGYIYLIT 1957
+ +DF +LYWI TI + DG + + + +LG + ++G ++
Sbjct: 1779 VGLAIDFPESKLYWISSGNHTINRCNLDGSELEVIDTMRSQLGKA-TALAIMGDKLWW-- 1835
Query: 1956 RQGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVS-HITHQ-KNPCQSDYCPS 1783
++ + G NK V V H + S + H+ NPC +
Sbjct: 1836 ----ADQVSEKMGTCNKADGSGSVVLRNSTTLVMHMKVYDESIQLEHEGTNPCSVNNGDC 1891
Query: 1782 NTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKC 1684
+ +C+P + C+C G + C
Sbjct: 1892 SQLCLPTSETT----RSCMCTAGYSLRSGQQAC 1920
Score = 50.4 bits (119), Expect = 6e-04
Identities = 48/173 (27%), Positives = 61/173 (34%), Gaps = 6/173 (3%)
Frame = -1
Query: 6432 TCNENEFRCQSG-ACIPSKARCNHMQDCNDASDEIG--CPFRNCSAL--NEFGMTGLINC 6268
TC+ +F C+ CI RC+ +DC D SDE CP NE +C
Sbjct: 27 TCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEH------SC 80
Query: 6267 ATTSQCIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCM 6088
T C+ S C+G DC DGSDE E + Q C+ T
Sbjct: 81 LGTELCVPMSRLCNGIQDCMDGSDEGAHCRELRVNCSRMGC--------QHHCVPT---- 128
Query: 6087 PKHWQCDGQPDC-ADGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDC 5932
P C + S + D K C F+ C C L DG C
Sbjct: 129 ------PSGPTCYCNNSFQLQADGKTCKDFD-ECSVYGTCSQLCTNTDGSFTC 174
Score = 40.8 bits (94), Expect = 0.45
Identities = 34/130 (26%), Positives = 49/130 (37%), Gaps = 10/130 (7%)
Frame = -1
Query: 6570 DEDTKYC---STRVCRPGYFNC-GNGLCIPEQKVCNRINDCANFADESNCTCNENEFRCQ 6403
DE + C + C P +C G LC+P ++CN I DC + +DE C E C
Sbjct: 59 DEAPEICPQSKAQRCPPNEHSCLGTELCVPMSRLCNGIQDCMDGSDE-GAHCRELRVNCS 117
Query: 6402 SGAC------IPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHP 6241
C PS C CN+ S ++ + C +E C+ C
Sbjct: 118 RMGCQHHCVPTPSGPTCY----CNN-SFQLQADGKTCKDFDE--------CSVYGTCSQL 164
Query: 6240 SWKCDGTNDC 6211
DG+ C
Sbjct: 165 CTNTDGSFTC 174
>gi|6678720|ref|NP_032538.1| low density lipoprotein receptor-related
protein 1; alpha 2-macroglobulin receptor [Mus musculus]
gi|109553|pir||S25111 alpha-2-macroglobulin receptor precursor -
mouse
gi|49942|emb|CAA47817.1| AM2 receptor [Mus musculus]
Length = 4545
Score = 845 bits (2184), Expect = 0.0
Identities = 616/1993 (30%), Positives = 873/1993 (42%), Gaps = 153/1993 (7%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCT---CNENEFRCQS 6400
DE YC++R C+ + C NG C+ CN ++ C + +DE C C EFRC+
Sbjct: 2556 DEKPSYCNSRRCKKTFRQCNNGRCVSNMLWCNGVDYCGDGSDEIPCNKTACGVGEFRCRD 2615
Query: 6399 GACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLI--NCATTSQCIHPSWKCD 6226
G+CI + +RCN DC DASDE+ C +CS+ G+ G++ C TS C PSW CD
Sbjct: 2616 GSCIGNSSRCNQFVDCEDASDEMNCSATDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCD 2675
Query: 6225 GTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCAD 6046
G NDC D SDE+DC V PR FAC + R C+P W CD + DC +
Sbjct: 2676 GANDCGDYSDERDC--------PGVKRPRC--PLNYFACPSGR-CIPMSWTCDKEDDCEN 2724
Query: 6045 GSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKG-GNAT 5869
G DE +C+ K C+ +F C++ + CI + CDG DC DG DE C+ K G ++
Sbjct: 2725 GEDETHCN-KFCSEAQFECQNHR-CISKQWLCDGSDDCGDGSDE---AAHCEGKTCGPSS 2779
Query: 5868 FRCTN-HRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACEL 5692
F C H C+P W CDG DC D A S C T C + C+
Sbjct: 2780 FSCPGTHVCVPERWLCDGDKDCTDGADE--SVTAGCLYNSTCDDREFMCQNRLCIPK--- 2834
Query: 5691 TAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRL-CDASVDCVDGSDEW 5515
+CD +DC+DG DE C PNE+ C +G+C+ S + CD DC D SDE
Sbjct: 2835 -HFVCDHDRDCADGSDESPECEYPT-CGPNEFRCANGRCLSSRQWECDGENDCHDHSDEA 2892
Query: 5514 VEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSST 5335
+ + P + C + L ++G C+ E LC+G+ DC G DE+ + S
Sbjct: 2893 PKNPHCTSPEHK-CNASSQFLCSSGR--CVAEALLCNGQDDCGDGSDERGCHVNECLSRK 2949
Query: 5334 RNSCDQTWNCQR-HAGFESCSCDDGYHLSPYDKKTCLRSPSCPKA-NCSHFCIDRRDVGH 5161
+ C Q +C+ GF+ C C G+ L D +TC C CS CI+ +
Sbjct: 2950 LSGCSQ--DCEDLKIGFK-CRCRPGFRLKD-DGRTCADLDECSTTFPCSQLCINTHG-SY 3004
Query: 5160 QCFCAPGYI-LSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLTNGVALD 4984
+C C GY + C+ E ++ + L+ +DG L L N VAL
Sbjct: 3005 KCLCVEGYAPRGGDPHSCKAVTDEEPFLIFANRYYLRKLNLDGSNYTLLKQGLNNAVALA 3064
Query: 4983 YDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDR 4804
+D + ++YWT V G+ I M + +V++ DG+AVDW+G N+Y+ D+
Sbjct: 3065 FDYREQMIYWTGVTTQGSM--IRRMHLNGSNVQVLHRTGLSNPDGLAVDWVGGNLYWCDK 3122
Query: 4803 NHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNE 4624
D I V + G + +L+ + L +PRA+V+D ++WTDWG + IGR+ MDGS
Sbjct: 3123 GRDTIEVSKLNGAYRTVLVS-SGLREPRALVVDVQNGYLYWTDWGDHSLIGRIGMDGSGR 3181
Query: 4623 QVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAV 4444
+I+ D I WPN L VD +R+Y+ DA DYI + DGS R +VL + HIFAL +
Sbjct: 3182 SIIV-DTKITWPNGLTVDYVTERIYWADAREDYIEFASLDGSNRHVVLSQDIPHIFALTL 3240
Query: 4443 FEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPC 4264
FEDYVYW+DW +I R HK TG N+ +LI +RPM + H Q HPC
Sbjct: 3241 FEDYVYWTDWETKSINRAHKTTGANKTLLISTL-HRPMDLHVFHALRQP----DVPNHPC 3295
Query: 4263 S-QPARCDNLCIPANTPDLTTSSDNFTCMCAQGFR--SEGRSCVSECKPNDFVCTKTYKC 4093
C NLC L + C C F +GR+CVS C + FVC K KC
Sbjct: 3296 KVNNGGCSNLC-------LLSPGGGHKCACPTNFYLGGDGRTCVSNCTASQFVC-KNDKC 3347
Query: 4092 ISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGV 3913
I WW+ CP F C GQF C +T C + +CDG
Sbjct: 3348 IPFWWKCDTEDDCGDHSDE----PPDCPEFKCRPGQFQC------STGICTNPAFICDGD 3397
Query: 3912 KDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCK 3733
DC DE A C+ C +QFKC + +CIP C+ + +C DG DE +C +C
Sbjct: 3398 NDCQDNSDE--ANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTCA 3455
Query: 3732 PDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCT-SGKCIPK 3556
P+ F C + +CIP+ + CD ++ C +G DEP +C + C ++F+C SG+CIP
Sbjct: 3456 PNQFQC---SITKRCIPRVWVCDRDNHCVDGSDEPANCTQM-TCGVDEFRCKDSGRCIPA 3511
Query: 3555 RRQCDGTLDCRDGSDEKGCKKEC-AIVCD--------NSCVHADDLCDGKKKCNDGSDED 3403
R +CDG DC DGSDE K+EC C+ N CV CD C D SDE
Sbjct: 3512 RWKCDGEDDCGDGSDEP--KEECDERTCEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDE- 3568
Query: 3402 EEACVIKQLLEKE----NRKC--GGFACDGIVDCEDGSDEKGCP---DLECHLASNKSLI 3250
E+C + E E N +C G + CDG DC DGSDEK C D++ + I
Sbjct: 3569 -ESCTPRPCSESEFFCANGRCIAGRWKCDGDHDCADGSDEKDCTPRCDMDQFQCKSGHCI 3627
Query: 3249 -----CDGTIDCSSGKDENNCHNNGES---NFFQCSMQTIKE--WQVCDGRWDCADGLDE 3100
CD DC G DE C + + FQC+ K W+ CDG DC D DE
Sbjct: 3628 PLRWPCDADADCMDGSDEEACGTGVRTCPLDEFQCNNTLCKPLAWK-CDGEDDCGDNSDE 3686
Query: 3099 SPEMCA------SRKARCFR------IG--------------------------YCDDKK 3034
+PE CA +R RC IG +C DKK
Sbjct: 3687 NPEECARFICPPNRPFRCKNDRVCLWIGRQCDGVDNCGDGTDEEDCEPPTAQNPHCKDKK 3746
Query: 3033 Q-------CLDVSTALCDGIRDCFDGSDENPIHCK----------DMCKGKYRCTNGRCI 2905
+ CL S+ C+ DC DGSDE MC + RC
Sbjct: 3747 EFLCRNQRCLS-SSLRCNMFDDCGDGSDEEDCSIDPKLTSCATNASMCGDEARCVRTEKA 3805
Query: 2904 DVSARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENE 2725
A EC FG C+Q W C CA + +T N
Sbjct: 3806 AYCACRSGFHTVPGQPGCQDIN-ECLRFGTCSQ-LWNKPKGGHLCSCARNFMKT---HNT 3860
Query: 2724 CEPLSKSAE-MFITNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRT--TL 2554
C+ + ++I + N + + S F ++ +D R T
Sbjct: 3861 CKAEGSEYQVLYIADDNEIRSL-FPGHPHSAYEQTFQGDESVRIDAMDVHVKAGRVYWTN 3919
Query: 2553 MYTVGIGNSRVDIRSKKWSDGL----IGSWGEEESTAGL-----ITYDFMHNNVYFTESS 2401
+T I + + + I + +GL I D++ NVY+T+S
Sbjct: 3920 WHTGTISYRSLPPAAPPTTSNRHRRQIDRGVTHLNISGLKMPRGIAIDWVAGNVYWTDSG 3979
Query: 2400 EQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILS 2221
I VA+ K + +TLI +++ VDP++ ++W+ P+I +
Sbjct: 3980 RDV----------IEVAQMKGENRKTLISGMIDEPHAIVVDPLRGTMYWSDWGNHPKIET 4029
Query: 2220 ANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGR 2041
A +DG + LV+ NI PT + +D+ NERLYW D I ++ +G
Sbjct: 4030 AAMDGTL-----------RETLVQDNIQWPTGLAVDYHNERLYWADAKLSVIGSIRLNGT 4078
Query: 2040 DRRTVRKFELG-DTPVTMDVLGGYIYLITR-QGSIHRMHKFTGKTNKYVQKIREVSPRIQ 1867
D + G P ++DV YIY +T + ++HKF G + Y +S
Sbjct: 4079 DPIVAADSKRGLSHPFSIDVFEDYIYGVTYINNRVFKIHKF-GHSPLY-NLTGGLSHASD 4136
Query: 1866 IRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKK 1687
+ + H +H +T NPC C + P P C C G+ + T
Sbjct: 4137 VVLYH--QHKQPEVT---NPCDRKKCEWLCLLSPSG-------PVCTCPNGKRLDNGTCV 4184
Query: 1686 CMQLREKDQEASQCGDYF--CYNNAGC----SPQKTCVCPPGFYGRQCEINECSETCWNG 1525
+ +A + G C+N C Q C C P + G +CE+++C E C NG
Sbjct: 4185 PVPSPTPPPDAPRPGTCTLQCFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCWEYCHNG 4244
Query: 1524 ETCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSYSFC 1345
TCA G T C CP+ +T C VC G C +C ++P CR
Sbjct: 4245 GTCAASPSGMPT---CRCPTGFTGPKCTAQVCAGYCSNNSTCTV--NQGNQPQCR----- 4294
Query: 1344 ECDKGWTGPHCRHKADAKVCYGHCFSGGAC----DG----------EGPL---------- 1237
C G+ G C+++ C G C + G C DG EGP
Sbjct: 4295 -CLPGFLGDRCQYRQ----CSGFCENFGTCQMAADGSRQCRCTVYFEGPRCEVNKCSRCL 4349
Query: 1236 -----------NLRCSCGDGLTGNRCQNCVGHECLNGGFCSYANSNRSLPHCICPSGFTG 1090
++ C+C DG C C+ H C NGG C+ +++ +P C CP TG
Sbjct: 4350 QGACVVNKQTGDVTCNCTDGRVAPSCLTCIDH-CSNGGSCTM--NSKMMPECQCPPHMTG 4406
Query: 1089 DHCEEYLCKDACP 1051
C+E + P
Sbjct: 4407 PRCQEQVVSQQQP 4419
Score = 377 bits (968), Expect = e-102
Identities = 313/1105 (28%), Positives = 443/1105 (39%), Gaps = 107/1105 (9%)
Frame = -1
Query: 6552 CSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC---TCNENEFRC-QSGACIP 6385
C CRPG F C G+C +C+ NDC + +DE+NC C ++F+C + CIP
Sbjct: 3370 CPEFKCRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCTNTNRCIP 3429
Query: 6384 SKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDGTNDCYD 6205
RCN +C D DE CP C A N+F C+ T +CI W CD N C D
Sbjct: 3430 GIFRCNGQDNCGDGEDERDCPEVTC-APNQF------QCSITKRCIPRVWVCDRDNHCVD 3482
Query: 6204 GSDE----------------KD----------CFVEFDATGGSVSAPRSCDAKT----QF 6115
GSDE KD C E D GS CD +T QF
Sbjct: 3483 GSDEPANCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQF 3542
Query: 6114 ACLATRTCMPKHWQCDGQPDCADGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRD 5935
C R C+P WQCD DC D SDE++C + C+ EF C + + CI KCDG D
Sbjct: 3543 RCKNNR-CVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFFCANGR-CIAGRWKCDGDHD 3600
Query: 5934 CPDGEDEHQCETECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAG 5755
C DG DE C CD F+C + CIP+ W CD DCMD GSDE C G
Sbjct: 3601 CADGSDEKDCTPRCDMD----QFQCKSGHCIPLRWPCDADADCMD-----GSDEEACGTG 3651
Query: 5754 RTSFHVPSRCADETCVVACELTAVLCDGIQDCSDGFDE--KNCASLDRQCKPNE-WMCDS 5584
+ + + T C+ A CDG DC D DE + CA C PN + C +
Sbjct: 3652 VRTCPLDEFQCNNTL---CKPLAWKCDGEDDCGDNSDENPEECARFI--CPPNRPFRCKN 3706
Query: 5583 GQ-CIDSGRLCDASVDCVDGSDEWVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLC 5407
+ C+ GR CD +C DG+DE E C C L N CL C
Sbjct: 3707 DRVCLWIGRQCDGVDNCGDGTDE--EDCEPPTAQNPHCKDKKEFLCRNQR--CLSSSLRC 3762
Query: 5406 DGRRDCMSGIDEQ---CDNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSP---- 5248
+ DC G DE+ D +C++ + C C R C+C G+H P
Sbjct: 3763 NMFDDCGDGSDEEDCSIDPKLTSCATNASMCGDEARCVRTEKAAYCACRSGFHTVPGQPG 3822
Query: 5247 -YDKKTCLRSPSCPKANCSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMV 5071
D CLR +C + ++ GH C CA ++ + N C+ + E ++L +
Sbjct: 3823 CQDINECLRFGTCSQL------WNKPKGGHLCSCARNFMKTHNT--CKAEGS-EYQVLYI 3873
Query: 5070 YGHRLKLFTIDGHAKATLLSNLTNGV-----ALDYDVKSDLVYWTDVAHDGNKA------ 4924
GH + A+D VK+ VYWT+ H G +
Sbjct: 3874 ADDNEIRSLFPGHPHSAYEQTFQGDESVRIDAMDVHVKAGRVYWTNW-HTGTISYRSLPP 3932
Query: 4923 ---GITSMSNQPNTYRVINSLPTKGID---GIAVDWLGRNIYYTDRNHDAIAVCDMRGRF 4762
TS ++ R + L G+ GIA+DW+ N+Y+TD D I V M+G
Sbjct: 3933 AAPPTTSNRHRRQIDRGVTHLNISGLKMPRGIAIDWVAGNVYWTDSGRDVIEVAQMKGEN 3992
Query: 4761 NRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNA 4582
+ L+ G +++P AIV+DPL+ ++W+DWG I MDG+ + ++QD I+WP
Sbjct: 3993 RKTLISGM-IDEPHAIVVDPLRGTMYWSDWGNHPKIETAAMDGTLRETLVQD-NIQWPTG 4050
Query: 4581 LAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVL--RGSVRHIFALAVFEDYVYWSDWHN 4408
LAVD +RLY+ DA I S +G+ + + + H F++ VFEDY+Y + N
Sbjct: 4051 LAVDYHNERLYWADAKLSVIGSIRLNGTDPIVAADSKRGLSHPFSIDVFEDYIYGVTYIN 4110
Query: 4407 HTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDNLCIP 4228
+ + ++HK G + + + H Q +PC + +C+ LC+
Sbjct: 4111 NRVFKIHKF-GHSPLYNLTGGLSHASDVVLYHQHKQ-----PEVTNPCDR-KKCEWLCL- 4162
Query: 4227 ANTPDLTTSSDNFTCMCAQGFRSEGRSCV---SECKPND--------FVCTKTYKCISSW 4081
S C C G R + +CV S P D C C +
Sbjct: 4163 -------LSPSGPVCTCPNGKRLDNGTCVPVPSPTPPPDAPRPGTCTLQCFNGGSCFLNA 4215
Query: 4080 WRXXXXXXXXXXXXXGYFVE---------GVCPPFPCIAGQFVC----GRTAQNATAQCL 3940
R ++ G C P +G C G T TAQ
Sbjct: 4216 RRQPKCRCQPRYTGDKCELDQCWEYCHNGGTCAASP--SGMPTCRCPTGFTGPKCTAQ-- 4271
Query: 3939 YASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCD---DG 3769
+ C C+ +P +C GD+ + + C+ C DG
Sbjct: 4272 VCAGYCSNNSTCTVNQGNQP------QCRCLPGFLGDRCQYRQCSGFCENFGTCQMAADG 4325
Query: 3768 SDEL---------NCEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEP---- 3628
S + CE+ C C G C+ + D +C +G+ P
Sbjct: 4326 SRQCRCTVYFEGPRCEVNKCS----RCLQGA----CVVNKQTGDVTCNCTDGRVAPSCLT 4377
Query: 3627 --DSCFGIGECTHEQFQCTSGKCIP 3559
D C G CT +C P
Sbjct: 4378 CIDHCSNGGSCTMNSKMMPECQCPP 4402
Score = 367 bits (941), Expect = 3e-99
Identities = 466/1871 (24%), Positives = 702/1871 (36%), Gaps = 245/1871 (13%)
Frame = -1
Query: 5214 CPKAN--CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTI 5041
C AN C C+ R C CA G +L+E+ CR E ++Y R L +I
Sbjct: 2160 CAVANGGCQQLCLYRGGGQRACACAHG-MLAEDGASCR-----EYAGYLLYSERTILKSI 2213
Query: 5040 DGHAKATLLS---------NLTNGVALDYDVKS-------DLVYWTDVAHDGNKAGITSM 4909
+ L + ++ N +AL +D ++ + ++++D+ H GN I
Sbjct: 2214 HLSDERNLNAPVQPFEDPEHMKNVIALAFDYRAGTSPGTPNRIFFSDI-HFGNIQQINDD 2272
Query: 4908 SNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIA---VCDMR-GRFNR---IL 4750
+ T ++ ++ + ++G+A +Y+T I V R G F R I
Sbjct: 2273 GSGRTT--IVENVGS--VEGLAYHRGWDTLYWTSYTTSTITRHTVDQTRPGAFERETVIT 2328
Query: 4749 LKGTPLNDPRAIVLDPLQALVFWTDWGA-SAHIGRMNMDGSNEQVILQDRTIRWPNALAV 4573
+ G + PRA VLD Q L+FWT+W I R + G+N +++ + IR PN LA+
Sbjct: 2329 MSGD--DHPRAFVLDECQNLMFWTNWNELHPSIMRAALSGANVLTLIE-KDIRTPNGLAI 2385
Query: 4572 DAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIER 4393
D A++LYF DA D I C YDGS R ++L+ H F LAV+ ++++W+DW ++R
Sbjct: 2386 DHRAEKLYFSDATLDKIERCEYDGSHRYVILKSEPVHPFGLAVYGEHIFWTDWVRRAVQR 2445
Query: 4392 VHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCS-QPARCDNLCIPANTP 4216
+K G++ K+L D +PMG V S PC C +LC
Sbjct: 2446 ANKYVGSDMKLLRVDIPQQPMGIIAVANDTNSC-----ELSPCRINNGGCQDLC------ 2494
Query: 4215 DLTTSSDNFTCMCAQG-FRSEGRSCV---SECKPNDFVCTKTYKCISSWWRXXXXXXXXX 4048
L T + C C G E +C S C+ D +CIS
Sbjct: 2495 -LLTHQGHVNCSCRGGRILQEDFTCRAVNSSCRAQDEFECANGECIS----------FSL 2543
Query: 4047 XXXXGYFVEGVCPPFPCIAGQFVCGRTAQNAT-AQCLYASKLCDGVKDCSGGDDEEPAFC 3871
+ P C +T + +C+ C+GV C G DE P C
Sbjct: 2544 TCDGVSHCKDKSDEKPSYCNSRRCKKTFRQCNNGRCVSNMLWCNGVDYCGDGSDEIP--C 2601
Query: 3870 ENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCKPDFFACFNGTAI-- 3697
C +F+C D CI +S C++ DC+D SDE+NC T C F G
Sbjct: 2602 NKTACGVGEFRCRDGS-CIGNSSRCNQFVDCEDASDEMNCSATDCSSYFRLGVKGVLFQP 2660
Query: 3696 ----SKCIPKEFYCDGEDDCPEGQDEPDSCFGIGE--CTHEQFQCTSGKCIPKRRQCDGT 3535
S C + CDG +DC + DE D C G+ C F C SG+CIP CD
Sbjct: 2661 CERTSLCYAPSWVCDGANDCGDYSDERD-CPGVKRPRCPLNYFACPSGRCIPMSWTCDKE 2719
Query: 3534 LDCRDGSDEKGCKKECA---IVCDNS-CVHADDLCDGKKKCNDGSDEDEEACVIKQLLEK 3367
DC +G DE C K C+ C N C+ LCDG C DGSDE
Sbjct: 2720 DDCENGEDETHCNKFCSEAQFECQNHRCISKQWLCDGSDDCGDGSDEAAHC--------- 2770
Query: 3366 ENRKCGG---------------FACDGIVDCEDGSDEK---------GCPDLEC----HL 3271
E + CG + CDG DC DG+DE C D E L
Sbjct: 2771 EGKTCGPSSFSCPGTHVCVPERWLCDGDKDCTDGADESVTAGCLYNSTCDDREFMCQNRL 2830
Query: 3270 ASNKSLICDGTIDCSSGKDEN-NC-HNNGESNFFQCS---MQTIKEWQVCDGRWDCADGL 3106
K +CD DC+ G DE+ C + N F+C+ + ++W+ CDG DC D
Sbjct: 2831 CIPKHFVCDHDRDCADGSDESPECEYPTCGPNEFRCANGRCLSSRQWE-CDGENDCHDHS 2889
Query: 3105 DESPEM--CASRKARCFRIG-YCDDKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKG 2935
DE+P+ C S + +C + +C+ LC+G DC DGSDE H +
Sbjct: 2890 DEAPKNPHCTSPEHKCNASSQFLCSSGRCV-AEALLCNGQDDCGDGSDERGCHVNECLSR 2948
Query: 2934 KYRCTNGRCIDVS----ARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCH 2767
K + C D+ R EC C+Q C + + + +C
Sbjct: 2949 KLSGCSQDCEDLKIGFKCRCRPGFRLKDDGRTCADLDECSTTFPCSQLC-INTHGSYKCL 3007
Query: 2766 CAPGYARTKNDENECEPLSKSAEMFITNGNRLHL--MSLENSQVSVLRPVFNIKMNLIPG 2593
C GYA D + C+ ++ E F+ NR +L ++L+ S ++L+ N
Sbjct: 3008 CVEGYAPRGGDPHSCKAVTDE-EPFLIFANRYYLRKLNLDGSNYTLLKQGLN-------N 3059
Query: 2592 GIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGL-----ITYDFMH 2428
+ +D +R ++Y G+ IR L GS + GL + D++
Sbjct: 3060 AVALAFD-YREQMIYWTGVTTQGSMIRRMH----LNGSNVQVLHRTGLSNPDGLAVDWVG 3114
Query: 2427 NNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTT 2248
N+Y+ + I V+K L+ + +L VD ++WT
Sbjct: 3115 GNLYWCDKGRDT----------IEVSKLNGAYRTVLVSSGLREPRALVVDVQNGYLYWTD 3164
Query: 2247 SAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRT 2068
I +DG +V+ I P + +D+ ER+YW D +
Sbjct: 3165 WGDHSLIGRIGMDGSG-----------RSIIVDTKITWPNGLTVDYVTERIYWADAREDY 3213
Query: 2067 IETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGK-------- 1915
IE S DG +R V ++ + + Y+Y SI+R HK TG
Sbjct: 3214 IEFASLDGSNRHVVLSQDIPHI-FALTLFEDYVYWTDWETKSINRAHKTTGANKTLLIST 3272
Query: 1914 -------------------------TNKYVQKIREVSPRIQIRVAHP--------AKHTV 1834
N + +SP + A P + V
Sbjct: 3273 LHRPMDLHVFHALRQPDVPNHPCKVNNGGCSNLCLLSPGGGHKCACPTNFYLGGDGRTCV 3332
Query: 1833 SHITHQKNPCQSDYC-PSNTVCVPDQDKNGIL-----IPKCLCGPGRFFEVSTKKCMQLR 1672
S+ T + C++D C P C + D P+ C PG+ F+ ST C
Sbjct: 3333 SNCTASQFVCKNDKCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQ-FQCSTGIC---- 3387
Query: 1671 EKDQEASQC-GDYFCYNNAGCSPQKTCVCPPGFYGRQCEINEC---------SETCWNGE 1522
A C GD C +N+ + VC P + + N C + C +GE
Sbjct: 3388 --TNPAFICDGDNDCQDNSDEANCDIHVCLPSQF-KCTNTNRCIPGIFRCNGQDNCGDGE 3444
Query: 1521 --------TCAVQEFGSTTNVVC-----------HC------PSNYTQSSCATN------ 1435
TCA +F + C HC P+N TQ +C +
Sbjct: 3445 DERDCPEVTCAPNQFQCSITKRCIPRVWVCDRDNHCVDGSDEPANCTQMTCGVDEFRCKD 3504
Query: 1434 ---------VCEGV--CGPRGSCKTVPCPKDEPHCRSYSF-CE---CDKG-WTGPH---C 1312
C+G CG C DE C Y F C+ C G W + C
Sbjct: 3505 SGRCIPARWKCDGEDDCGDGSDEPKEEC--DERTCEPYQFRCKNNRCVPGRWQCDYDNDC 3562
Query: 1311 RHKADAKVC-------------YGHCFSG-GACDGEGPLNLRCSCGDGLTGNRCQ---NC 1183
+D + C G C +G CDG+ C DG C +
Sbjct: 3563 GDNSDEESCTPRPCSESEFFCANGRCIAGRWKCDGDH------DCADGSDEKDCTPRCDM 3616
Query: 1182 VGHECLNGGFCSYANSNRSLPHCI---CPSGFTGDHCEEYLCKDACPFGSKCTYDITKPM 1012
+C +G HCI P D C + ++AC G + T P+
Sbjct: 3617 DQFQCKSG-------------HCIPLRWPCDADAD-CMDGSDEEACGTGVR-----TCPL 3657
Query: 1011 DPITCS---CEQNA--AAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCK----CLPRF 859
D C+ C+ A DC + P C R + P P +CK CL +
Sbjct: 3658 DEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEEC---ARFICPPNRPFRCKNDRVCL--W 3712
Query: 858 AGPRCDVPVQCDDYCTNNSKCTITNGTHFECDCKPGF---------KGLRCEQETKCSEC 706
G +CD C D T+ C + C K F LRC C +
Sbjct: 3713 IGRQCDGVDNCGD-GTDEEDCEPPTAQNPHCKDKKEFLCRNQRCLSSSLRCNMFDDCGDG 3771
Query: 705 SNEAKCIKKPSGTVICQCPQGLGGEYCEKITATSCHQLECKNGGYCLKPDPSANRTSPTC 526
S+E C P K+T+ + + C + C++ + +A C
Sbjct: 3772 SDEEDCSIDP------------------KLTSCATNASMCGDEARCVRTEKAA-----YC 3808
Query: 525 LCSPGFKGLLCSSNACE--NFCLHDGNCTLDEYFEPQ----CECYQAFI--GDRCQYRIH 370
C GF + C+ N CL G C+ + +P+ C C + F+ + C+
Sbjct: 3809 ACRSGFH-TVPGQPGCQDINECLRFGTCS-QLWNKPKGGHLCSCARNFMKTHNTCKAEGS 3866
Query: 369 QHAVIFSDDDS 337
++ V++ DD+
Sbjct: 3867 EYQVLYIADDN 3877
Score = 357 bits (915), Expect = 3e-96
Identities = 255/818 (31%), Positives = 351/818 (42%), Gaps = 38/818 (4%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCI--PEQKVCNRINDCANFADESNCT----------C 6427
D + T CR C + LC+ P + C D D C C
Sbjct: 797 DAHEQQVGTNKCRVNNGGCSS-LCLATPGSRQCACAEDQVLDTDGVTCLANPSYVPPPQC 855
Query: 6426 NENEFRCQSGACIPSKARCNHMQDCNDASDEIG--CPFRNCSALNEFGMTGLINCATTSQ 6253
+F C + CI + +C+ DC D SDE C C + C ++
Sbjct: 856 QPGQFACANNRCIQERWKCDGDNDCLDNSDEAPALCHQHTCPS-------DRFKCEN-NR 907
Query: 6252 CIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKT----QFACLATRTCMP 6085
CI W CDG NDC + DE + +C A+T QF+C + R C+P
Sbjct: 908 CIPNRWLCDGDNDCGNSEDESNA---------------TCSARTCPPNQFSCASGR-CIP 951
Query: 6084 KHWQCDGQPDCADGSDEK-NCDAKKCTSF-EFSCESSKKCIPLEQKCDGRRDCPDGEDEH 5911
W CD DC D SDE +C C +F+C + + CI + +CD DC D DE
Sbjct: 952 ISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNGR-CININWRCDNDNDCGDNSDEA 1010
Query: 5910 QCETECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPS 5731
C C S F+C + RCIP W CDG +DC D SDE + P
Sbjct: 1011 GCSHSCSS----TQFKCNSGRCIPEHWTCDGDNDCGDY-----SDETHANCTNQATRPPG 1061
Query: 5730 RCADETCVVACELTAVL------CDGIQDCSDGFDEKNCASLDRQCKPN-EWMC-DSGQC 5575
C + C L + CDG DC D DEK+C + C PN ++ C DS +C
Sbjct: 1062 GCHSDE--FQCPLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPNVKFGCKDSARC 1119
Query: 5574 IDSGRLCDASVDCVDGSDEWVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRR 5395
I +CD DC D SDE PP C N T CL +LCDG+
Sbjct: 1120 ISKAWVCDGDSDCEDNSDEENCEALACRPPSHPC--------ANNTSVCLPPDKLCDGKD 1171
Query: 5394 DCMSGIDEQ--CDNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRS 5221
DC G DE CD CS C + G CSC G L D TC
Sbjct: 1172 DCGDGSDEGELCDQ----CSLNNGGCSHNCSVAPGEGIV-CSCPLGMELGS-DNHTCQIQ 1225
Query: 5220 PSCPK-ANCSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFT 5044
C K CS C D+ +C C G++L + + CR D + I+ H ++
Sbjct: 1226 SYCAKHLKCSQKC-DQNKFSVKCSCYEGWVLEPDGETCRSLDPFKLFIIFSNRHEIRRID 1284
Query: 5043 IDGHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPT 4864
+ + L+ L N +ALD+ + +YWTD D G + ++ V+
Sbjct: 1285 LHKGDYSVLVPGLRNTIALDFHLSQSALYWTDAVEDKIYRGKLLDNGALTSFEVVIQYGL 1344
Query: 4863 KGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVF 4684
+G+AVDW+ NIY+ + N D I V + G LL G + PRAI LDP ++F
Sbjct: 1345 ATPEGLAVDWIAGNIYWVESNLDQIEVAKLDGTLRTTLLAG-DIEHPRAIALDPRDGILF 1403
Query: 4683 WTDWGAS-AHIGRMNMDGSNEQVILQDR-TIRWPNALAVDAPAQRLYFGDAHRDYIASCN 4510
WTDW AS I +M G+ + I ++ + N L VD +R+ + DA D I S
Sbjct: 1404 WTDWDASLPRIEAASMSGAGRRTIHRETGSGGCANGLTVDYLEKRILWIDARSDAIYSAR 1463
Query: 4509 YDGSKRRMVLRGS--VRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYR 4336
YDGS VLRG + H FA+ ++ VYW+DW +T+ + +K TG N V +Q +
Sbjct: 1464 YDGSGHMEVLRGHEFLSHPFAVTLYGGEVYWTDWRTNTLAKANKWTGHNVTV-VQRTNTQ 1522
Query: 4335 PMGFKIVHPSLQSMGSLKTARHPCSQ---PARCDNLCI 4231
P ++ HPS Q M A +PC C +LC+
Sbjct: 1523 PFDLQVYHPSRQPM-----APNPCEANGGRGPCSHLCL 1555
Score = 329 bits (843), Expect = 6e-88
Identities = 307/1244 (24%), Positives = 494/1244 (39%), Gaps = 89/1244 (7%)
Frame = -1
Query: 5259 HLSPYDKKTCLRSPSCPK------ANCSHFCI-DRRDVGHQCFCAPGYILSENQKDCRRN 5101
H+ ++ +RS +C CS C+ C C G+ L + K C++
Sbjct: 464 HIYHQRRQPRVRSHACENDQYGKPGGCSDICLLANSHKARTCRCRSGFSLGSDGKSCKKP 523
Query: 5100 DTIEAEILMVYGHRLK--LFTIDGHAKAT-----LLSNLTNGVALDYDVKSDLVYWTDVA 4942
E E+ +VYG + +D AK + NL N ALD+ ++ +Y+ D
Sbjct: 524 ---EHELFLVYGKGRPGIIRGMDMGAKVPDEHMIPIENLMNPRALDFHAETGFIYFADTT 580
Query: 4941 HDGNKAGITSMSNQPNTYR-VINSLPTKGIDGIAVDWLGRNIYYTD---RNHDAIAVCDM 4774
+ + T R I ++G+AVDW+G N+Y+TD + ++A +
Sbjct: 581 -----SYLIGRQKIDGTERETILKDGIHNVEGVAVDWMGDNLYWTDDGPKKTISVARLEK 635
Query: 4773 RGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDW------GASAHIGRMNMDGSNEQVIL 4612
+ + L++G + PRAIV+DPL ++WTDW + R MDGS+ + +
Sbjct: 636 AAQTRKTLIEGK-MTHPRAIVVDPLNGWMYWTDWEEDPKDSRRGRLERAWMDGSHRDIFV 694
Query: 4611 QDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRG-SVRHIFALAVFED 4435
+T+ WPN L++D PA RLY+ DA D I + +G+ R++V G + H F L +
Sbjct: 695 TSKTVLWPNGLSLDIPAGRLYWVDAFYDRIETILLNGTDRKIVYEGPELNHAFGLCHHGN 754
Query: 4434 YVYWSDWHNHTIERVHK-ITGTNRKVLIQDKQYRPM-GFKIVHPSLQSMGSLKTARHPCS 4261
Y++W+++ + ++ R+ + + G V + + P+ ++ Q +G+ K
Sbjct: 755 YLFWTEYRSGSVYRLERGVAGAPPTVTLLRSERPPIFEIRMYDAHEQQVGTNKCR----V 810
Query: 4260 QPARCDNLCIPANTPDLTTSSDNFTCMCAQGFRSEGRSCVS--------ECKPNDFVCTK 4105
C +LC+ T S C Q ++G +C++ +C+P F C
Sbjct: 811 NNGGCSSLCL------ATPGSRQCACAEDQVLDTDGVTCLANPSYVPPPQCQPGQFACAN 864
Query: 4104 TYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKL 3925
+CI W+
Sbjct: 865 N-RCIQERWK-------------------------------------------------- 873
Query: 3924 CDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELN--C 3751
CDG DC DE PA C C +FKC + +CIP +CD + DC + DE N C
Sbjct: 874 CDGDNDCLDNSDEAPALCHQHTCPSDRFKC-ENNRCIPNRWLCDGDNDCGNSEDESNATC 932
Query: 3750 EITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSG 3571
+C P+ F+C +G +CIP + CD +DDC + DE SC QF C +G
Sbjct: 933 SARTCPPNQFSCASG----RCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNG 988
Query: 3570 KCIPKRRQCDGTLDCRDGSDEKGCKKECA---IVCDNS-CVHADDLCDGKKKCNDGSDED 3403
+CI +CD DC D SDE GC C+ C++ C+ CDG C D SDE
Sbjct: 989 RCININWRCDNDNDCGDNSDEAGCSHSCSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDET 1048
Query: 3402 EEACVIKQLLEKENRKCGG------------------FACDGIVDCEDGSDEKGCPDL-- 3283
C + R GG + CDG DC D SDEK C +
Sbjct: 1049 HANCT-----NQATRPPGGCHSDEFQCPLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTH 1103
Query: 3282 -----------ECHLASNKSLICDGTIDCSSGKDENNCHNNG-ESNFFQCSMQT---IKE 3148
+ +K+ +CDG DC DE NC C+ T +
Sbjct: 1104 VCDPNVKFGCKDSARCISKAWVCDGDSDCEDNSDEENCEALACRPPSHPCANNTSVCLPP 1163
Query: 3147 WQVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDE 2968
++CDG+ DC DG DE E+C G C +C GSD
Sbjct: 1164 DKLCDGKDDCGDGSDEG-ELCDQCS---LNNGGCSHNCSVAPGEGIVCSCPLGMELGSDN 1219
Query: 2967 NPIHCKDMCKGKYRCTNGRCIDVSARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAF 2788
+ + C + C+QKC
Sbjct: 1220 HTCQIQSYCAKHLK-------------------------------------CSQKCDQN- 1241
Query: 2787 NHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNR--LHLMSLENSQVSVLRPVFNI 2614
+ +C C G+ + D C L ++FI NR + + L SVL P
Sbjct: 1242 KFSVKCSCYEGWV-LEPDGETCRSLD-PFKLFIIFSNRHEIRRIDLHKGDYSVLVPG--- 1296
Query: 2613 KMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGLIT--- 2443
+ I + + ++ L +T + + R K +G + S+ E GL T
Sbjct: 1297 ----LRNTIALDFHLSQSALYWTDAVEDK--IYRGKLLDNGALTSF-EVVIQYGLATPEG 1349
Query: 2442 --YDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIK 2269
D++ N+Y+ ES+ I VAK T TL+ ++A+DP
Sbjct: 1350 LAVDWIAGNIYWVESNLD----------QIEVAKLDGTLRTTLLAGDIEHPRAIALDPRD 1399
Query: 2268 RLIFWTT-SAPVPRILSANLDG---KPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNE 2101
++FWT A +PRI +A++ G + I + +G + + +D+ +
Sbjct: 1400 GILFWTDWDASLPRIEAASMSGAGRRTIHRETGSGGCAN------------GLTVDYLEK 1447
Query: 2100 RLYWIDVLKRTIETVSFDGRDRRTV-RKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHK 1927
R+ WID I + +DG V R E P + + GG +Y R ++ + +K
Sbjct: 1448 RILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYGGEVYWTDWRTNTLAKANK 1507
Query: 1926 FTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSD 1795
+TG VQ R + ++V HP++ ++ NPC+++
Sbjct: 1508 WTGHNVTVVQ--RTNTQPFDLQVYHPSRQPMA-----PNPCEAN 1544
Score = 203 bits (517), Expect = 4e-50
Identities = 149/518 (28%), Positives = 239/518 (45%), Gaps = 26/518 (5%)
Frame = -1
Query: 5619 RQCKPNEWMC-DSGQCIDSGRLCDASVDCVDGSDEWVEICSLSEPPRRGCPSG-WSCLLT 5446
+ C P ++ C D CI G CD DC DGSDE EIC S+ R CP SCL
Sbjct: 26 KTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQR--CPPNEHSCL-- 81
Query: 5445 NGTIGCLQEQQLCDGRRDCMSGIDE--QCDNPQGNCSSTRNSCDQTWNCQRHAGFESCSC 5272
GT C+ +LC+G +DCM G DE C + NCS R C +C +C C
Sbjct: 82 -GTELCVPMSRLCNGIQDCMDGSDEGAHCRELRANCS--RMGCQH--HCVPTPSGPTCYC 136
Query: 5271 DDGYHLSPYDKKTCLRSPSCPK-ANCSHFCIDRRDVGHQCFCAPGYILSENQKDCR-RND 5098
+ + L D KTC C CS C + D C C GY+L + + C+ +N+
Sbjct: 137 NSSFQLEA-DGKTCKDFDECSVYGTCSQLCTNT-DGSFTCGCVEGYLLQPDNRSCKAKNE 194
Query: 5097 TIEAEILMVYGHRLKLFT--IDGHAKATLLSNLTNGV-ALDYDVKSDLVYWTDVAHDGNK 4927
++ +++ + + + G +T+ T A+D+ ++ V W V +
Sbjct: 195 PVDRPPVLLIANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWVHVGDSAAQ 254
Query: 4926 -----AGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRF 4762
A + + + + + SL ++ +A+DWL N Y+ D D I VC+ G
Sbjct: 255 TQLKCARMPGLKGFVDEHTINISLSLHHVEQMAIDWLTGNFYFVDDIDDRIFVCNRNGD- 313
Query: 4761 NRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNA 4582
+ L L +P+ I LDP VF+TD+G + R +MDG N + L D I +P+
Sbjct: 314 TCVTLLDLELYNPKGIALDPAMGKVFFTDYGQIPKVERCDMDGQN-RTKLVDSKIVFPHG 372
Query: 4581 LAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRG-SVRHIFALAVFEDYVYWSDWHNH 4405
+ +D ++ +Y+ DA+ DYI +Y+G R+ +++G + H++ L VFE+Y+Y ++ N
Sbjct: 373 ITLDLVSRLVYWADAYLDYIEVVDYEGKGRQTIIQGILIEHLYGLTVFENYLYATNSDNA 432
Query: 4404 TIERVHKITGTNR----KVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPC-----SQPA 4252
++ + NR + + + + I H Q + H C +P
Sbjct: 433 NTQQKTSVIRVNRFNSTEYQVVTRVDKGGALHIYHQRRQP----RVRSHACENDQYGKPG 488
Query: 4251 RCDNLCIPANTPDLTTSSDNFTCMCAQGFR--SEGRSC 4144
C ++C+ AN S TC C GF S+G+SC
Sbjct: 489 GCSDICLLAN------SHKARTCRCRSGFSLGSDGKSC 520
Score = 173 bits (439), Expect = 4e-41
Identities = 103/277 (37%), Positives = 134/277 (48%), Gaps = 10/277 (3%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADES-NC---TCNE-NEFR 6409
+DE CS R C P F+C +G CIP C+ +DC + +DES +C TC +F
Sbjct: 925 EDESNATCSARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQFT 984
Query: 6408 CQSGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKC 6229
C +G CI RC++ DC D SDE GC +CS+ C + +CI W C
Sbjct: 985 CNNGRCININWRCDNDNDCGDNSDEAGCS-HSCSSTQ-------FKC-NSGRCIPEHWTC 1035
Query: 6228 DGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCA 6049
DG NDC D SDE + T + P C + +F C C+P W+CDG DC
Sbjct: 1036 DGDNDCGDYSDE----THANCTNQATRPPGGCHS-DEFQCPLDGLCIPLRWRCDGDTDCM 1090
Query: 6048 DGSDEKNCD--AKKC-TSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGG 5878
D SDEK+C+ C + +F C+ S +CI CDG DC D DE CE
Sbjct: 1091 DSSDEKSCEGVTHVCDPNVKFGCKDSARCISKAWVCDGDSDCEDNSDEENCEALACRPPS 1150
Query: 5877 NATFRCTNHR--CIPMAWRCDGTDDCMDNAKSLGSDE 5773
+ C N+ C+P CDG DDC D GSDE
Sbjct: 1151 HP---CANNTSVCLPPDKLCDGKDDCGD-----GSDE 1179
Score = 155 bits (393), Expect = 1e-35
Identities = 110/387 (28%), Positives = 180/387 (46%), Gaps = 15/387 (3%)
Frame = -1
Query: 5259 HLSPYDKKTCLRSP-----SCPKANCSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDT 5095
H+ YD+ L S +CS C+ + C C GY L Q+ C +
Sbjct: 1833 HMKVYDESIQLEHEGTNPCSVNNGDCSQLCLPTSETTRSCMCTAGYSLRSGQQAC---EG 1889
Query: 5094 IEAEILMVYGHRLKLFTIDGHAKATLL---SNLTNGVALDYDVKSDLVYWTDVAHDGNKA 4924
+ + +L ++ +D + K+ L S + V +D+ ++D +YW D+
Sbjct: 1890 VGSFLLYSVHEGIRGIPLDPNDKSDALVPVSGTSLAVGIDFHAENDTIYWVDM------- 1942
Query: 4923 GITSMSNQPNTYRVINSLPTKGI---DGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRI 4753
G++++S + T GI +GIAVDW+ NIY+TD+ D I V + G F +
Sbjct: 1943 GLSTISRAKRDQTWREDVVTNGIGRVEGIAVDWIAGNIYWTDQGFDVIEVARLNGSFRYV 2002
Query: 4752 LLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAV 4573
++ L+ PRAI + P + +FWT+WG I R +DG+ E+V+L + +I WPN ++V
Sbjct: 2003 VI-SQGLDKPRAITVHPEKGYLFWTEWGHYPRIERSRLDGT-ERVVLVNVSISWPNGISV 2060
Query: 4572 DAPAQRLYFGDAHRDYIASCNYD-GSKRRMVLRGSVRHIFALAVFEDYVYWSD--WHNHT 4402
D +LY+ DA D I + + G R +VL + +F+++VFED++YWSD N +
Sbjct: 2061 DYQGGKLYWCDARMDKIERIDLETGENREVVLSSNNMDMFSVSVFEDFIYWSDRTHANGS 2120
Query: 4401 IERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDNLCIPAN 4222
I+R K T+ L + K+ + Q ++ + C LC
Sbjct: 2121 IKRGCKDNATDSVPLRTGIGVQLKDIKVFNRDRQKGTNVCAVAN-----GGCQQLC---- 2171
Query: 4221 TPDLTTSSDNFTCMCAQGFRSE-GRSC 4144
L C CA G +E G SC
Sbjct: 2172 ---LYRGGGQRACACAHGMLAEDGASC 2195
Score = 139 bits (350), Expect = 9e-31
Identities = 88/258 (34%), Positives = 126/258 (48%), Gaps = 14/258 (5%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCT--CNENEFRCQS 6400
D+ D + C+ R C F C NG CI + C+ +DCA+ +DE +CT C+ ++F+C+S
Sbjct: 3564 DNSDEESCTPRPCSESEFFCANGRCIAGRWKCDGDHDCADGSDEKDCTPRCDMDQFQCKS 3623
Query: 6399 GACIPSKARCNHMQDCNDASDEIGC--PFRNCSALNEFGMTGLINCATTSQCIHPSWKCD 6226
G CIP + C+ DC D SDE C R C L+EF C T C +WKCD
Sbjct: 3624 GHCIPLRWPCDADADCMDGSDEEACGTGVRTC-PLDEF------QCNNT-LCKPLAWKCD 3675
Query: 6225 GTNDCYDGSDE--KDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDC 6052
G +DC D SDE ++C A C F C R C+ QCDG +C
Sbjct: 3676 GEDDCGDNSDENPEEC------------ARFICPPNRPFRCKNDRVCLWIGRQCDGVDNC 3723
Query: 6051 ADGSDEKNCDAKKCTS------FEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQC--ETE 5896
DG+DE++C+ + EF C +++C+ +C+ DC DG DE C + +
Sbjct: 3724 GDGTDEEDCEPPTAQNPHCKDKKEFLCR-NQRCLSSSLRCNMFDDCGDGSDEEDCSIDPK 3782
Query: 5895 CDSKGGNATFRCTNHRCI 5842
S NA+ RC+
Sbjct: 3783 LTSCATNASMCGDEARCV 3800
Score = 129 bits (325), Expect = 7e-28
Identities = 92/341 (26%), Positives = 129/341 (36%)
Frame = -1
Query: 1173 ECLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCS 994
+C NGG C + N+ R P C C +TGD CE C +
Sbjct: 4204 QCFNGGSC-FLNARRQ-PKCRCQPRYTGDKCELDQCWE---------------------- 4239
Query: 993 CEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYC 814
+CHNGG C +P C+C F GP+C V C YC
Sbjct: 4240 ---------------------YCHNGGTCAASPSGMPTCRCPTGFTGPKCTAQV-CAGYC 4277
Query: 813 TNNSKCTITNGTHFECDCKPGFKGLRCEQETKCSECSNEAKCIKKPSGTVICQCPQGLGG 634
+NNS CT+ G +C C PGF G RC+ C N C G+ C+C G
Sbjct: 4278 SNNSTCTVNQGNQPQCRCLPGFLGDRCQYRQCSGFCENFGTCQMAADGSRQCRCTVYFEG 4337
Query: 633 EYCEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCLHDG 454
CE + C Q G C+ + + TC C+ G C + C + C + G
Sbjct: 4338 PRCEVNKCSRCLQ------GACVVNKQTGD---VTCNCTDGRVAPSCLT--CIDHCSNGG 4386
Query: 453 NCTLDEYFEPQCECYQAFIGDRCQYRIHQHAVIFSDDDSGWIKSFXXXXXXXXXXXXXXX 274
+CT++ P+C+C G RCQ + + S G + S
Sbjct: 4387 SCTMNSKMMPECQCPPHMTGPRCQEQ------VVSQQQPGHMASILIPLLLLLLLLLVAG 4440
Query: 273 IFANRSNRFAVFRQFRHNPLQNQGAPVDQFSNPAYLIDEGG 151
+ R + F+H + N GA + NP Y + EGG
Sbjct: 4441 VVFWYKRRVRGAKGFQHQRMTN-GAMNVEIGNPTYKMYEGG 4480
Score = 125 bits (313), Expect = 2e-26
Identities = 96/365 (26%), Positives = 165/365 (44%), Gaps = 13/365 (3%)
Frame = -1
Query: 5199 CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAK-- 5026
CSH C+ + C L ++ C E + ++Y ++++ +D A
Sbjct: 1550 CSHLCLINYNRTVSWACPHLMKLHKDNTTC-----YEFKKFLLYARQMEIRGVDLDAPYY 1604
Query: 5025 ----ATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKG 4858
+ + ++ N LDYD + VYW+DV K + + + S
Sbjct: 1605 NYIISFTVPDIDNVTVLDYDAREQRVYWSDVRTQAIKRAFINGTG----VETVVSADLPN 1660
Query: 4857 IDGIAVDWLGRNIYYT--DRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVF 4684
G+AVDW+ RN+++T D N I V + G F +++G L P +V+ PL+ ++
Sbjct: 1661 AHGLAVDWVSRNLFWTSYDTNKKQINVARLDGSFKNAVVQG--LEQPHGLVVHPLRGKLY 1718
Query: 4683 WTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYD 4504
WTD +I NMDGSN ++ + + P LA+D P +LY+ + I CN D
Sbjct: 1719 WTD---GDNISMANMDGSNHTLLFSGQ--KGPVGLAIDFPESKLYWISSGNHTINRCNLD 1773
Query: 4503 GSKRRMV--LRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPM 4330
GS+ ++ +R + ALA+ D ++W+D + + +K G+ V++++ M
Sbjct: 1774 GSELEVIDTMRSQLGKATALAIMGDKLWWADQVSEKMGTCNKADGSG-SVVLRNSTTLVM 1832
Query: 4329 GFKIVHPSLQSMGSLKTARHPCS-QPARCDNLCIPANTPDLTTSSDNFTCMCAQGF--RS 4159
K+ S+Q +PCS C LC+P TS +CMC G+ RS
Sbjct: 1833 HMKVYDESIQLE---HEGTNPCSVNNGDCSQLCLP-------TSETTRSCMCTAGYSLRS 1882
Query: 4158 EGRSC 4144
++C
Sbjct: 1883 GQQAC 1887
Score = 116 bits (291), Expect = 6e-24
Identities = 113/465 (24%), Positives = 182/465 (38%), Gaps = 18/465 (3%)
Frame = -1
Query: 3153 KEWQVCDGRWDCADGLDESPEMCASRKA-RCFRIGY-CDDKKQCLDVSTALCDGIRDCFD 2980
K W+ CDG DC DG DE+PE+C KA RC + C + C+ +S LC+GI+DC D
Sbjct: 44 KGWR-CDGERDCPDGSDEAPEICPQSKAQRCPPNEHSCLGTELCVPMS-RLCNGIQDCMD 101
Query: 2979 GSDENPIHCKDMCKGKYRC-TNGRCIDVSARXXXXXXXXXXXXXXXXGA----ECHHFGV 2815
GSDE HC+++ R C+ + EC +G
Sbjct: 102 GSDEG-AHCRELRANCSRMGCQHHCVPTPSGPTCYCNSSFQLEADGKTCKDFDECSVYGT 160
Query: 2814 CAQKCWMAFNHTARCHCAPGYARTKNDENEC----EPLSKSAEMFITNGNRLHLMSLENS 2647
C+Q C + + C C GY + D C EP+ + + I N + L +
Sbjct: 161 CSQLCTNT-DGSFTCGCVEGYL-LQPDNRSCKAKNEPVDRPPVLLIANSQNILATYLSGA 218
Query: 2646 QVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEE 2467
QVS + P + +DF Y T VG ++ ++ + GL G E
Sbjct: 219 QVSTITPTSTRQTT----AMDFSY-ANETVCWVHVGDSAAQTQLKCAR-MPGLKGFVDEH 272
Query: 2466 ESTAGL-------ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNS 2308
L + D++ N YF + D I+V + TL+
Sbjct: 273 TINISLSLHHVEQMAIDWLTGNFYFVD----------DIDDRIFVCNRNGDTCVTLLDLE 322
Query: 2307 TGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPT 2128
+A+DP +F+T +P++ ++DG Q LV+ I P
Sbjct: 323 LYNPKGIALDPAMGKVFFTDYGQIPKVERCDMDG-----------QNRTKLVDSKIVFPH 371
Query: 2127 SMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITRQG 1948
+ LD + +YW D IE V ++G+ R+T+ + L + + V Y+Y
Sbjct: 372 GITLDLVSRLVYWADAYLDYIEVVDYEGKGRQTIIQGILIEHLYGLTVFENYLYATNSDN 431
Query: 1947 SIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQK 1813
+ + + N++ +V R+ K HI HQ+
Sbjct: 432 ANTQQKTSVIRVNRFNSTEYQVVTRVD-------KGGALHIYHQR 469
Score = 108 bits (271), Expect = 1e-21
Identities = 195/882 (22%), Positives = 315/882 (35%), Gaps = 69/882 (7%)
Frame = -1
Query: 2820 GVCAQKCWMAFNHTAR-CHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQ 2644
G C+ C +A +H AR C C G++ +D C+ + G + ++
Sbjct: 488 GGCSDICLLANSHKARTCRCRSGFS-LGSDGKSCKKPEHELFLVYGKGRPGIIRGMDMGA 546
Query: 2643 VSVLRPVFNIKMNLIPGGIDF----GYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSW 2476
+ I+ + P +DF G+ F T Y +G R DG+
Sbjct: 547 KVPDEHMIPIENLMNPRALDFHAETGFIYFADTTSYLIGRQKIDGTERETILKDGIHNVE 606
Query: 2475 GEEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTST--RTLIVNSTG 2302
G + D+M +N+Y+T+ + I VA+ + + +TLI
Sbjct: 607 G--------VAVDWMGDNLYWTDDGPKK---------TISVARLEKAAQTRKTLIEGKMT 649
Query: 2301 TINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSM 2122
++ VDP+ ++WT P+ + G+ + + + GS + + + P +
Sbjct: 650 HPRAIVVDPLNGWMYWTDWEEDPK---DSRRGR-LERAWMDGSHRDIFVTSKTVLWPNGL 705
Query: 2121 VLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT-RQGS 1945
LD RLYW+D IET+ +G DR+ V + + + G Y++ R GS
Sbjct: 706 SLDIPAGRLYWVDAFYDRIETILLNGTDRKIVYEGPELNHAFGLCHHGNYLFWTEYRSGS 765
Query: 1944 IHRMHKFTGKTNKYVQKIREVSPRI-QIRV--AHPAKHTVSHITHQKNPCQSDYC---PS 1783
++R+ + V +R P I +IR+ AH + + C S C P
Sbjct: 766 VYRLERGVAGAPPTVTLLRSERPPIFEIRMYDAHEQQVGTNKCRVNNGGC-SSLCLATPG 824
Query: 1782 NTVCVPDQDK-----------NGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCGDY 1636
+ C +D+ N +P C PG+ F + +C+Q R K GD
Sbjct: 825 SRQCACAEDQVLDTDGVTCLANPSYVPPPQCQPGQ-FACANNRCIQERWKCD-----GDN 878
Query: 1635 FCYNNAGCSPQ--KTCVCPPGFYGRQCEINECSETCW---NGETCAVQEFGSTTNVVCH- 1474
C +N+ +P CP + +CE N C W C E +N C
Sbjct: 879 DCLDNSDEAPALCHQHTCPSDRF--KCENNRCIPNRWLCDGDNDCGNSE--DESNATCSA 934
Query: 1473 --CPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHKA 1300
CP N Q SCA+ C + + C D+ +C R
Sbjct: 935 RTCPPN--QFSCASGRCIPI--------SWTCDLDD---------DCGD-------RSDE 968
Query: 1299 DAKVCYGHCF-------SGGACDGEGPLNLRC----SCGDGLTGNRCQNCVGHECLNGGF 1153
A Y CF + G C +N RC CGD C H C + F
Sbjct: 969 SASCAYPTCFPLTQFTCNNGRCIN---INWRCDNDNDCGDNSDEAGC----SHSCSSTQF 1021
Query: 1152 CSYANSNRSLP-HCICP-SGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCSCEQNA 979
NS R +P H C GD+ +E + CT T+P P C ++
Sbjct: 1022 --KCNSGRCIPEHWTCDGDNDCGDYSDE--------THANCTNQATRP--PGGCHSDEFQ 1069
Query: 978 AAHNTDCSPICQKQPNW-CHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNS 802
+ C P+ W C C+D+ C+ + P +V C D S
Sbjct: 1070 CPLDGLCIPL-----RWRCDGDTDCMDSSD-EKSCEGVTHVCDP--NVKFGCKDSARCIS 1121
Query: 801 KCTITNGTHFECDCKPGFKGLRCEQ---ETKCSECSNEAKCIKKPSGTVICQCPQGLGGE 631
K + +G + DC+ CE C+N P +C G
Sbjct: 1122 KAWVCDG---DSDCEDNSDEENCEALACRPPSHPCANNTSVCLPPD--KLCDGKDDCGDG 1176
Query: 630 YCEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCS----------SNA 481
E C Q NGG S C +PG +G++CS ++
Sbjct: 1177 SDE---GELCDQCSLNNGG-----------CSHNCSVAPG-EGIVCSCPLGMELGSDNHT 1221
Query: 480 C--ENFCLHDGNCTL---DEYFEPQCECYQAFI----GDRCQ 382
C +++C C+ F +C CY+ ++ G+ C+
Sbjct: 1222 CQIQSYCAKHLKCSQKCDQNKFSVKCSCYEGWVLEPDGETCR 1263
Score = 89.4 bits (220), Expect = 1e-15
Identities = 43/114 (37%), Positives = 62/114 (53%), Gaps = 5/114 (4%)
Frame = -1
Query: 6165 TGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADGSDE-----KNCDAKKCTSF 6001
+G ++ AP++C K QFAC TC+ K W+CDG+ DC DGSDE A++C
Sbjct: 18 SGATMDAPKTCSPK-QFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPN 76
Query: 6000 EFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNATFRCTNHRCIP 5839
E SC ++ C+P+ + C+G +DC DG DE C N + H C+P
Sbjct: 77 EHSCLGTELCVPMSRLCNGIQDCMDGSDE---GAHCRELRANCSRMGCQHHCVP 127
Score = 68.9 bits (167), Expect = 2e-09
Identities = 55/184 (29%), Positives = 74/184 (39%), Gaps = 15/184 (8%)
Frame = -1
Query: 3858 CTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDEL-----NCEITSCKPDFFACFNGTAIS 3694
C+ QF C D+ CI CD E+DC DGSDE + C P+ +C GT +
Sbjct: 28 CSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEHSCL-GTEL- 85
Query: 3693 KCIPKEFYCDGEDDCPEGQDEPDSCFGIGE------CTHEQFQCTSGKCIPKRRQCDGTL 3532
C+P C+G DC +G DE C + C H SG C+ +
Sbjct: 86 -CVPMSRLCNGIQDCMDGSDEGAHCRELRANCSRMGCQHHCVPTPSGPTC----YCNSSF 140
Query: 3531 DCRDGSDEKGCK--KECAI--VCDNSCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKE 3364
+D K CK EC++ C C + DG C CV LL+ +
Sbjct: 141 QLE--ADGKTCKDFDECSVYGTCSQLCTNT----DGSFTC---------GCVEGYLLQPD 185
Query: 3363 NRKC 3352
NR C
Sbjct: 186 NRSC 189
Score = 63.9 bits (154), Expect = 5e-08
Identities = 75/303 (24%), Positives = 118/303 (38%), Gaps = 8/303 (2%)
Frame = -1
Query: 2820 GVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQV 2641
G C+Q C T C C GY+ ++ + CE + + G R + N +
Sbjct: 1856 GDCSQLCLPTSETTRSCMCTAGYS-LRSGQQACEGVGSFLLYSVHEGIRGIPLD-PNDKS 1913
Query: 2640 SVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEES 2461
L PV + + GIDF + +Y V +G S + R+K+ +W E+
Sbjct: 1914 DALVPVSGTSLAV---GIDFHAE---NDTIYWVDMGLSTIS-RAKRDQ-----TWREDVV 1961
Query: 2460 TAGL-----ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTI 2296
T G+ I D++ N+Y+T+ FD I VA+ + +I
Sbjct: 1962 TNGIGRVEGIAVDWIAGNIYWTDQG-------FDV---IEVARLNGSFRYVVISQGLDKP 2011
Query: 2295 NSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVL 2116
++ V P K +FWT PRI + LDG LV +I P + +
Sbjct: 2012 RAITVHPEKGYLFWTEWGHYPRIERSRLDG-----------TERVVLVNVSISWPNGISV 2060
Query: 2115 DFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITR---QGS 1945
D+ +LYW D IE + + + R V ++ V +IY R GS
Sbjct: 2061 DYQGGKLYWCDARMDKIERIDLETGENREVVLSSNNMDMFSVSVFEDFIYWSDRTHANGS 2120
Query: 1944 IHR 1936
I R
Sbjct: 2121 IKR 2123
Score = 62.0 bits (149), Expect = 2e-07
Identities = 44/157 (28%), Positives = 56/157 (35%), Gaps = 20/157 (12%)
Frame = -1
Query: 6270 CATTSQCIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAK-------TQFA 6112
C CI W+CDG DC DGSDE AP C + +
Sbjct: 35 CRDQITCISKGWRCDGERDCPDGSDE---------------APEICPQSKAQRCPPNEHS 79
Query: 6111 CLATRTCMPKHWQCDGQPDCADGSDE--------KNCDAKKCTSFEFSCESSKKCI---P 5965
CL T C+P C+G DC DGSDE NC C S C
Sbjct: 80 CLGTELCVPMSRLCNGIQDCMDGSDEGAHCRELRANCSRMGCQHHCVPTPSGPTCYCNSS 139
Query: 5964 LEQKCDGR--RDCPDGEDEHQCETECDSKGGNATFRC 5860
+ + DG+ +D + C C + G+ T C
Sbjct: 140 FQLEADGKTCKDFDECSVYGTCSQLCTNTDGSFTCGC 176
Score = 58.2 bits (139), Expect = 3e-06
Identities = 62/255 (24%), Positives = 87/255 (33%), Gaps = 20/255 (7%)
Frame = -1
Query: 5913 HQCETECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVP 5734
HQ C +GG R + + C N+ DE +CA G
Sbjct: 2498 HQGHVNCSCRGG---------RILQEDFTCRAV-----NSSCRAQDEFECANGE------ 2537
Query: 5733 SRCADETCVVACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLC 5554
C ++ CDG+ C D DEK R+CK C++G+C+ + C
Sbjct: 2538 -----------CISFSLTCDGVSHCKDKSDEKPSYCNSRRCKKTFRQCNNGRCVSNMLWC 2586
Query: 5553 DASVDCVDGSDEW---VEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMS 5383
+ C DGSDE C + E C G C+ C+ DC
Sbjct: 2587 NGVDYCGDGSDEIPCNKTACGVGE---FRCRDG----------SCIGNSSRCNQFVDCED 2633
Query: 5382 GIDEQCDNPQGNCSSTRNS--------------CDQTWNCQRHAGFESCSCDDGYHLSPY 5245
DE NCS+T S C++T C S CD Y
Sbjct: 2634 ASDEM------NCSATDCSSYFRLGVKGVLFQPCERTSLCYA----PSWVCDGANDCGDY 2683
Query: 5244 -DKKTC--LRSPSCP 5209
D++ C ++ P CP
Sbjct: 2684 SDERDCPGVKRPRCP 2698
Score = 56.2 bits (134), Expect = 1e-05
Identities = 31/103 (30%), Positives = 43/103 (41%), Gaps = 11/103 (10%)
Frame = -1
Query: 4008 PFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFE---CTEAQFK 3838
P C QF C C+ CDG +DC G DE P C + C +
Sbjct: 25 PKTCSPKQFAC-----RDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEHS 79
Query: 3837 CGDKKKCIPLTSVCDKEKDCDDGSDE--------LNCEITSCK 3733
C + C+P++ +C+ +DC DGSDE NC C+
Sbjct: 80 CLGTELCVPMSRLCNGIQDCMDGSDEGAHCRELRANCSRMGCQ 122
Score = 52.0 bits (123), Expect = 2e-04
Identities = 49/173 (28%), Positives = 62/173 (35%), Gaps = 6/173 (3%)
Frame = -1
Query: 6432 TCNENEFRCQSG-ACIPSKARCNHMQDCNDASDEIG--CPFRNCSAL--NEFGMTGLINC 6268
TC+ +F C+ CI RC+ +DC D SDE CP NE +C
Sbjct: 27 TCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEH------SC 80
Query: 6267 ATTSQCIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCM 6088
T C+ S C+G DC DGSDE E A + Q C+ T
Sbjct: 81 LGTELCVPMSRLCNGIQDCMDGSDEGAHCRELRANCSRMGC--------QHHCVPT---- 128
Query: 6087 PKHWQCDGQPDC-ADGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDC 5932
P C + S + D K C F+ C C L DG C
Sbjct: 129 ------PSGPTCYCNSSFQLEADGKTCKDFD-ECSVYGTCSQLCTNTDGSFTC 174
Score = 48.5 bits (114), Expect = 0.002
Identities = 77/393 (19%), Positives = 139/393 (34%), Gaps = 14/393 (3%)
Frame = -1
Query: 2820 GVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQV 2641
G C+ C + +N T C P + D C K L+ +E V
Sbjct: 1548 GPCSHLCLINYNRTVSWAC-PHLMKLHKDNTTCYEFKKFL---------LYARQMEIRGV 1597
Query: 2640 SVLRPVFNIKMNLIPGGID----FGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWG 2473
+ P +N ++ ID YD + ++ D+R++ I G
Sbjct: 1598 DLDAPYYNYIISFTVPDIDNVTVLDYDAREQRVYWS--------DVRTQAIKRAFINGTG 1649
Query: 2472 EEE------STAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVN 2311
E A + D++ N+++T S + N+ +Q N+ D S + +V
Sbjct: 1650 VETVVSADLPNAHGLAVDWVSRNLFWT-SYDTNK-----KQINV---ARLDGSFKNAVVQ 1700
Query: 2310 STGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEP 2131
+ L V P++ ++WT I AN+DG + L+ P
Sbjct: 1701 GLEQPHGLVVHPLRGKLYWTDG---DNISMANMDGS------------NHTLLFSGQKGP 1745
Query: 2130 TSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTV--RKFELGDTPVTMDVLGGYIYLIT 1957
+ +DF +LYWI TI + DG + + + +LG + ++G ++
Sbjct: 1746 VGLAIDFPESKLYWISSGNHTINRCNLDGSELEVIDTMRSQLGKA-TALAIMGDKLWW-- 1802
Query: 1956 RQGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVS-HITHQ-KNPCQSDYCPS 1783
++ + G NK V V H + S + H+ NPC +
Sbjct: 1803 ----ADQVSEKMGTCNKADGSGSVVLRNSTTLVMHMKVYDESIQLEHEGTNPCSVNNGDC 1858
Query: 1782 NTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKC 1684
+ +C+P + C+C G + C
Sbjct: 1859 SQLCLPTSETT----RSCMCTAGYSLRSGQQAC 1887
Score = 40.4 bits (93), Expect = 0.59
Identities = 34/130 (26%), Positives = 49/130 (37%), Gaps = 10/130 (7%)
Frame = -1
Query: 6570 DEDTKYC---STRVCRPGYFNC-GNGLCIPEQKVCNRINDCANFADESNCTCNENEFRCQ 6403
DE + C + C P +C G LC+P ++CN I DC + +DE C E C
Sbjct: 59 DEAPEICPQSKAQRCPPNEHSCLGTELCVPMSRLCNGIQDCMDGSDE-GAHCRELRANCS 117
Query: 6402 SGAC------IPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHP 6241
C PS C CN +S ++ + C +E C+ C
Sbjct: 118 RMGCQHHCVPTPSGPTCY----CN-SSFQLEADGKTCKDFDE--------CSVYGTCSQL 164
Query: 6240 SWKCDGTNDC 6211
DG+ C
Sbjct: 165 CTNTDGSFTC 174
>gi|4758686|ref|NP_002323.1| low density lipoprotein-related protein
1; alpha-2-macroglobulin receptor [Homo sapiens]
gi|1708865|sp|Q07954|LRP1_HUMAN Low-density lipoprotein
receptor-related protein 1 precursor (LRP)
(Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E
receptor) (APOER) (CD91)
gi|88083|pir||S02392 alpha-2-macroglobulin receptor precursor - human
gi|34339|emb|CAA32112.1| LDL-receptor related precursor (AA -19 to
4525) [Homo sapiens]
gi|3493576|gb|AAC64265.1| lipoprotein receptor-related protein [Homo
sapiens]
Length = 4544
Score = 830 bits (2145), Expect = 0.0
Identities = 610/2001 (30%), Positives = 868/2001 (42%), Gaps = 161/2001 (8%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCT---CNENEFRCQS 6400
DE YC++R C+ + C NG C+ CN +DC + +DE C C EFRC+
Sbjct: 2555 DEKPSYCNSRRCKKTFRQCSNGRCVSNMLWCNGADDCGDGSDEIPCNKTACGVGEFRCRD 2614
Query: 6399 GACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLI--NCATTSQCIHPSWKCD 6226
G CI + +RCN DC DASDE+ C +CS+ G+ G++ C TS C PSW CD
Sbjct: 2615 GTCIGNSSRCNQFVDCEDASDEMNCSATDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCD 2674
Query: 6225 GTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCAD 6046
G NDC D SDE+DC V PR FAC + R C+P W CD + DC
Sbjct: 2675 GANDCGDYSDERDC--------PGVKRPRC--PLNYFACPSGR-CIPMSWTCDKEDDCEH 2723
Query: 6045 GSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKG-GNAT 5869
G DE +C+ K C+ +F C++ + CI + CDG DC DG DE C+ K G ++
Sbjct: 2724 GEDETHCN-KFCSEAQFECQNHR-CISKQWLCDGSDDCGDGSDE---AAHCEGKTCGPSS 2778
Query: 5868 FRCTN-HRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACEL 5692
F C H C+P W CDG DC D A S C T C + C+
Sbjct: 2779 FSCPGTHVCVPERWLCDGDKDCADGADE--SIAAGCLYNSTCDDREFMCQNRQCIPK--- 2833
Query: 5691 TAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRL-CDASVDCVDGSDEW 5515
+CD +DC+DG DE C P+E+ C +G+C+ S + CD DC D SDE
Sbjct: 2834 -HFVCDHDRDCADGSDESPECEYPT-CGPSEFRCANGRCLSSRQWECDGENDCHDQSDEA 2891
Query: 5514 VEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSST 5335
+ + P + C + L ++G C+ E LC+G+ DC DE+ + S
Sbjct: 2892 PKNPHCTSPEHK-CNASSQFLCSSGR--CVAEALLCNGQDDCGDSSDERGCHINECLSRK 2948
Query: 5334 RNSCDQTWNCQR-HAGFESCSCDDGYHLSPYDKKTCLRSPSCPKA-NCSHFCIDRRDVGH 5161
+ C Q +C+ GF+ C C G+ L D +TC C CS CI+ +
Sbjct: 2949 LSGCSQ--DCEDLKIGFK-CRCRPGFRLKD-DGRTCADVDECSTTFPCSQRCINTHG-SY 3003
Query: 5160 QCFCAPGYI-LSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLTNGVALD 4984
+C C GY + C+ E ++ + L+ +DG L L N VALD
Sbjct: 3004 KCLCVEGYAPRGGDPHSCKAVTDEEPFLIFANRYYLRKLNLDGSNYTLLKQGLNNAVALD 3063
Query: 4983 YDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDR 4804
+D + ++YWTDV G+ I M + +V++ DG+AVDW+G N+Y+ D+
Sbjct: 3064 FDYREQMIYWTDVTTQGSM--IRRMHLNGSNVQVLHRTGLSNPDGLAVDWVGGNLYWCDK 3121
Query: 4803 NHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNE 4624
D I V + G + +L+ + L +PRA+V+D ++WTDWG + IGR+ MDGS+
Sbjct: 3122 GRDTIEVSKLNGAYRTVLVS-SGLREPRALVVDVQNGYLYWTDWGDHSLIGRIGMDGSSR 3180
Query: 4623 QVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAV 4444
VI+ D I WPN L +D +R+Y+ DA DYI + DGS R +VL + HIFAL +
Sbjct: 3181 SVIV-DTKITWPNGLTLDYVTERIYWADAREDYIEFASLDGSNRHVVLSQDIPHIFALTL 3239
Query: 4443 FEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPC 4264
FEDYVYW+DW +I R HK TGTN+ +LI +RPM + H Q HPC
Sbjct: 3240 FEDYVYWTDWETKSINRAHKTTGTNKTLLI-STLHRPMDLHVFHALRQP----DVPNHPC 3294
Query: 4263 S-QPARCDNLCIPANTPDLTTSSDNFTCMCAQGF--RSEGRSCVSECKPNDFVCTKTYKC 4093
C NLC L + C C F S+GR+CVS C + FVC K KC
Sbjct: 3295 KVNNGGCSNLC-------LLSPGGGHKCACPTNFYLGSDGRTCVSNCTASQFVC-KNDKC 3346
Query: 4092 ISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGV 3913
I WW+ CP F C GQF C +T C + +CDG
Sbjct: 3347 IPFWWKCDTEDDCGDHSDE----PPDCPEFKCRPGQFQC------STGICTNPAFICDGD 3396
Query: 3912 KDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCK 3733
DC DE A C+ C +QFKC + +CIP C+ + +C DG DE +C +C
Sbjct: 3397 NDCQDNSDE--ANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTCA 3454
Query: 3732 PDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQC-TSGKCIPK 3556
P+ F C + +CIP+ + CD ++DC +G DEP +C + C ++F+C SG+CIP
Sbjct: 3455 PNQFQC---SITKRCIPRVWVCDRDNDCVDGSDEPANCTQM-TCGVDEFRCKDSGRCIPA 3510
Query: 3555 RRQCDGTLDCRDGSDEKGCKKEC-AIVCD--------NSCVHADDLCDGKKKCNDGSDED 3403
R +CDG DC DGSDE K+EC C+ N CV CD C D S D
Sbjct: 3511 RWKCDGEDDCGDGSDEP--KEECDERTCEPYQFRCKNNRCVPGRWQCDYDNDCGDNS--D 3566
Query: 3402 EEACVIKQLLEKE----NRKC--GGFACDGIVDCEDGSDEKGCP---DLECHLASNKSLI 3250
EE+C + E E N +C G + CDG DC DGSDEK C D++ + I
Sbjct: 3567 EESCTPRPCSESEFSCANGRCIAGRWKCDGDHDCADGSDEKDCTPRCDMDQFQCKSGHCI 3626
Query: 3249 -----CDGTIDCSSGKDENNCHNNGES---NFFQCSMQTIK--EWQVCDGRWDCADGLDE 3100
CD DC G DE C + + FQC+ K W+ CDG DC D DE
Sbjct: 3627 PLRWRCDADADCMDGSDEEACGTGVRTCPLDEFQCNNTLCKPLAWK-CDGEDDCGDNSDE 3685
Query: 3099 SPEMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDE--------NPIHCKDM 2944
+PE CA R C + + CL + CDG +C DG+DE + HCKD
Sbjct: 3686 NPEECARFVCPPNRPFRCKNDRVCLWIGRQ-CDGTDNCGDGTDEEDCEPPTAHTTHCKD- 3743
Query: 2943 CKGKYRCTNGRCIDVSARXXXXXXXXXXXXXXXXGAE------CHHFGVCAQKC-WMAFN 2785
K ++ C N RC+ S R + + +C + +
Sbjct: 3744 -KKEFLCRNQRCLSSSLRCNMFDDCGDGSDEEDCSIDPKLTSCATNASICGDEARCVRTE 3802
Query: 2784 HTARCHCAPGYARTK-----NDENECEPLSKSAEMFITNGNRLHLMS------------- 2659
A C C G+ D NEC +++ N HL S
Sbjct: 3803 KAAYCACRSGFHTVPGQPGCQDINECLRFGTCSQL-CNNTKGGHLCSCARNFMKTHNTCK 3861
Query: 2658 LENSQVSVLRPVFNIKM-NLIPGGIDFGYD-VFRTTLMYTVGIGNSRVDIRSKKWSDGLI 2485
E S+ VL + ++ +L PG Y+ F+ + + V W+
Sbjct: 3862 AEGSEYQVLYIADDNEIRSLFPGHPHSAYEQAFQGDESVRIDAMDVHVKAGRVYWT---- 3917
Query: 2484 GSWGEEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNST 2305
+W G I+Y + T S+ R + D L ++
Sbjct: 3918 -NW-----HTGTISYRSLPPAAPPTTSNRHRRQI--------------DRGVTHLNISGL 3957
Query: 2304 GTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTS 2125
+A+D + ++WT S G+ + + + + K L+ I EP +
Sbjct: 3958 KMPRGIAIDWVAGNVYWTDS------------GRDVIEVAQMKGENRKTLISGMIDEPHA 4005
Query: 2124 MVLDFSNERLYWIDVLKR-TIETVSFDGRDRRT--------------------------- 2029
+V+D +YW D IET + DG R T
Sbjct: 4006 IVVDPLRGTMYWSDWGNHPKIETAAMDGTLRETLVQDNIQWPTGLAVDYHNERLYWADAK 4065
Query: 2028 ---VRKFELGDT--------------PVTMDVLGGYIYLITR-QGSIHRMHKFTGKTNKY 1903
+ L T P ++DV YIY +T + ++HKF +
Sbjct: 4066 LSVIGSIRLNGTDPIVAADSKRGLSHPFSIDVFEDYIYGVTYINNRVFKIHKF--GHSPL 4123
Query: 1902 VQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLC 1723
V +S + + H +H +T NPC C + P P C C
Sbjct: 4124 VNLTGGLSHASDVVLYH--QHKQPEVT---NPCDRKKCEWLCLLSPSG-------PVCTC 4171
Query: 1722 GPGRFFEVSTKKCMQLREKDQEASQCG--DYFCYNNAGC----SPQKTCVCPPGFYGRQC 1561
G+ + T + +A + G + C+N C Q C C P + G +C
Sbjct: 4172 PNGKRLDNGTCVPVPSPTPPPDAPRPGTCNLQCFNGGSCFLNARRQPKCRCQPRYTGDKC 4231
Query: 1560 EINECSETCWNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCP 1381
E+++C E C NG TCA G T C CP+ +T C VC G C +C
Sbjct: 4232 ELDQCWEHCRNGGTCAASPSGMPT---CRCPTGFTGPKCTQQVCAGYCANNSTCTV--NQ 4286
Query: 1380 KDEPHCRSYSFCECDKGWTGPHCRHKADAKVC--YGHC---------------FSGGACD 1252
++P CR C G+ G C+++ + C +G C F G C+
Sbjct: 4287 GNQPQCR------CLPGFLGDRCQYRQCSGYCENFGTCQMAADGSRQCRCTAYFEGSRCE 4340
Query: 1251 G-------EGPL-------NLRCSCGDGLTGNRCQNCVGHECLNGGFCSYANSNRSLPHC 1114
EG ++ C+C DG C CVGH C NGG C+ +++ +P C
Sbjct: 4341 VNKCSRCLEGACVVNKQSGDVTCNCTDGRVAPSCLTCVGH-CSNGGSCTM--NSKMMPEC 4397
Query: 1113 ICPSGFTGDHCEEYLCKDACP 1051
CP TG CEE++ P
Sbjct: 4398 QCPPHMTGPRCEEHVFSQQQP 4418
Score = 375 bits (962), Expect = e-101
Identities = 270/857 (31%), Positives = 379/857 (43%), Gaps = 41/857 (4%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGN-GLCIPEQKVCNRINDCANFADESNC---TCNENEFRC 6406
D+ D C VC P F C N CIP CN ++C + DE +C TC N+F+C
Sbjct: 3401 DNSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTCAPNQFQC 3460
Query: 6405 Q-SGACIPSKARCNHMQDCNDASDE-IGCPFRNCSALNEFGMTGLINCATTSQCIHPSWK 6232
+ CIP C+ DC D SDE C C ++EF C + +CI WK
Sbjct: 3461 SITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTC-GVDEF------RCKDSGRCIPARWK 3513
Query: 6231 CDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKT----QFACLATRTCMPKHWQCDG 6064
CDG +DC DGSDE CD +T QF C R C+P WQCD
Sbjct: 3514 CDGEDDCGDGSDE---------------PKEECDERTCEPYQFRCKNNR-CVPGRWQCDY 3557
Query: 6063 QPDCADGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSK 5884
DC D SDE++C + C+ EFSC ++ +CI KCDG DC DG DE C CD
Sbjct: 3558 DNDCGDNSDEESCTPRPCSESEFSC-ANGRCIAGRWKCDGDHDCADGSDEKDCTPRCDMD 3616
Query: 5883 GGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVV 5704
F+C + CIP+ WRCD DCMD GSDE C G + + + T
Sbjct: 3617 ----QFQCKSGHCIPLRWRCDADADCMD-----GSDEEACGTGVRTCPLDEFQCNNT--- 3664
Query: 5703 ACELTAVLCDGIQDCSDGFDE--KNCASLDRQCKPNE-WMCDSGQ-CIDSGRLCDASVDC 5536
C+ A CDG DC D DE + CA C PN + C + + C+ GR CD + +C
Sbjct: 3665 LCKPLAWKCDGEDDCGDNSDENPEECARF--VCPPNRPFRCKNDRVCLWIGRQCDGTDNC 3722
Query: 5535 VDGSDEWVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQ---C 5365
DG+DE E C C L N CL C+ DC G DE+
Sbjct: 3723 GDGTDE--EDCEPPTAHTTHCKDKKEFLCRNQR--CLSSSLRCNMFDDCGDGSDEEDCSI 3778
Query: 5364 DNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSP-----YDKKTCLRSPSCPKAN 5200
D +C++ + C C R C+C G+H P D CLR
Sbjct: 3779 DPKLTSCATNASICGDEARCVRTEKAAYCACRSGFHTVPGQPGCQDINECLRF-----GT 3833
Query: 5199 CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKAT 5020
CS C + + GH C CA ++ + N C+ + E ++L + GH +
Sbjct: 3834 CSQLCNNTKG-GHLCSCARNFMKTHN--TCKAEGS-EYQVLYIADDNEIRSLFPGHPHSA 3889
Query: 5019 LLSNLTNGV-----ALDYDVKSDLVYWTDVAHDGN---------KAGITSMSNQPNTYRV 4882
A+D VK+ VYWT+ H G TS ++ R
Sbjct: 3890 YEQAFQGDESVRIDAMDVHVKAGRVYWTN-WHTGTISYRSLPPAAPPTTSNRHRRQIDRG 3948
Query: 4881 INSLPTKGID---GIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIV 4711
+ L G+ GIA+DW+ N+Y+TD D I V M+G + L+ G +++P AIV
Sbjct: 3949 VTHLNISGLKMPRGIAIDWVAGNVYWTDSGRDVIEVAQMKGENRKTLISGM-IDEPHAIV 4007
Query: 4710 LDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHR 4531
+DPL+ ++W+DWG I MDG+ + ++QD I+WP LAVD +RLY+ DA
Sbjct: 4008 VDPLRGTMYWSDWGNHPKIETAAMDGTLRETLVQD-NIQWPTGLAVDYHNERLYWADAKL 4066
Query: 4530 DYIASCNYDGSKRRMVL--RGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVL 4357
I S +G+ + + + H F++ VFEDY+Y + N+ + ++HK G + V
Sbjct: 4067 SVIGSIRLNGTDPIVAADSKRGLSHPFSIDVFEDYIYGVTYINNRVFKIHKF-GHSPLVN 4125
Query: 4356 IQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDNLCIPANTPDLTTSSDNFTCMC 4177
+ + H Q +PC + +C+ LC+ S C C
Sbjct: 4126 LTGGLSHASDVVLYHQHKQ-----PEVTNPCDR-KKCEWLCL--------LSPSGPVCTC 4171
Query: 4176 AQGFRSEGRSCVSECKP 4126
G R + +CV P
Sbjct: 4172 PNGKRLDNGTCVPVPSP 4188
Score = 370 bits (951), Expect = e-100
Identities = 262/820 (31%), Positives = 357/820 (42%), Gaps = 40/820 (4%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCI--PEQKVCNRINDCANFADESNCT----------C 6427
D + T CR C + LC+ P + C D AD C C
Sbjct: 796 DAQQQQVGTNKCRVNNGGCSS-LCLATPGSRQCACAEDQVLDADGVTCLANPSYVPPPQC 854
Query: 6426 NENEFRCQSGACIPSKARCNHMQDCNDASDEIG--CPFRNCSALNEFGMTGLINCATTSQ 6253
EF C + CI + +C+ DC D SDE C C + C ++
Sbjct: 855 QPGEFACANSRCIQERWKCDGDNDCLDNSDEAPALCHQHTCPS-------DRFKCEN-NR 906
Query: 6252 CIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKT----QFACLATRTCMP 6085
CI W CDG NDC + DE + +C A+T QF+C + R C+P
Sbjct: 907 CIPNRWLCDGDNDCGNSEDESNA---------------TCSARTCPPNQFSCASGR-CIP 950
Query: 6084 KHWQCDGQPDCADGSDEK-NCDAKKCTSF-EFSCESSKKCIPLEQKCDGRRDCPDGEDEH 5911
W CD DC D SDE +C C +F+C + + CI + +CD DC D DE
Sbjct: 951 ISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNGR-CININWRCDNDNDCGDNSDEA 1009
Query: 5910 QCETECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPS 5731
C C S F+C + RCIP W CDG +DC D SDE + P
Sbjct: 1010 GCSHSCSS----TQFKCNSGRCIPEHWTCDGDNDCGDY-----SDETHANCTNQATRPPG 1060
Query: 5730 RCADETCVVACELTAVL------CDGIQDCSDGFDEKNCASLDRQCKPN-EWMC-DSGQC 5575
C T C L + CDG DC D DEK+C + C P+ ++ C DS +C
Sbjct: 1061 GC--HTDEFQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPSVKFGCKDSARC 1118
Query: 5574 IDSGRLCDASVDCVDGSDEWVEICS--LSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDG 5401
I +CD DC D SDE E C PP C N T CL +LCDG
Sbjct: 1119 ISKAWVCDGDNDCEDNSDE--ENCESLACRPPSHPC--------ANNTSVCLPPDKLCDG 1168
Query: 5400 RRDCMSGIDEQ--CDNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCL 5227
DC G DE CD CS C + G CSC G L P D TC
Sbjct: 1169 NDDCGDGSDEGELCDQ----CSLNNGGCSHNCSVAPGEGIV-CSCPLGMELGP-DNHTCQ 1222
Query: 5226 RSPSCPK-ANCSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKL 5050
C K CS C D+ +C C G++L + + CR D + I+ H ++
Sbjct: 1223 IQSYCAKHLKCSQKC-DQNKFSVKCSCYEGWVLEPDGESCRSLDPFKPFIIFSNRHEIRR 1281
Query: 5049 FTIDGHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSL 4870
+ + L+ L N +ALD+ + +YWTDV D G + ++ V+
Sbjct: 1282 IDLHKGDYSVLVPGLRNTIALDFHLSQSALYWTDVVEDKIYRGKLLDNGALTSFEVVIQY 1341
Query: 4869 PTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQAL 4690
+G+AVDW+ NIY+ + N D I V + G LL G + PRAI LDP +
Sbjct: 1342 GLATPEGLAVDWIAGNIYWVESNLDQIEVAKLDGTLRTTLLAG-DIEHPRAIALDPRDGI 1400
Query: 4689 VFWTDWGAS-AHIGRMNMDGSNEQVILQDR-TIRWPNALAVDAPAQRLYFGDAHRDYIAS 4516
+FWTDW AS I +M G+ + + ++ + WPN L VD +R+ + DA D I S
Sbjct: 1401 LFWTDWDASLPRIEAASMSGAGRRTVHRETGSGGWPNGLTVDYLEKRILWIDARSDAIYS 1460
Query: 4515 CNYDGSKRRMVLRGS--VRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQ 4342
YDGS VLRG + H FA+ ++ VYW+DW +T+ + +K TG N V +Q
Sbjct: 1461 ARYDGSGHMEVLRGHEFLSHPFAVTLYGGEVYWTDWRTNTLAKANKWTGHNVTV-VQRTN 1519
Query: 4341 YRPMGFKIVHPSLQSMGSLKTARHPCSQ---PARCDNLCI 4231
+P ++ HPS Q M A +PC C +LC+
Sbjct: 1520 TQPFDLQVYHPSRQPM-----APNPCEANGGQGPCSHLCL 1554
Score = 365 bits (938), Expect = 6e-99
Identities = 457/1844 (24%), Positives = 691/1844 (36%), Gaps = 218/1844 (11%)
Frame = -1
Query: 5214 CPKAN--CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTI 5041
C AN C C+ R C CA G +L+E+ CR E ++Y R L +I
Sbjct: 2159 CAVANGGCQQLCLYRGRGQRACACAHG-MLAEDGASCR-----EYAGYLLYSERTILKSI 2212
Query: 5040 DGHAKATLLS---------NLTNGVALDYDVKS-------DLVYWTDVAHDGNKAGITSM 4909
+ L + ++ N +AL +D ++ + ++++D+ H GN I
Sbjct: 2213 HLSDERNLNAPVQPFEDPEHMKNVIALAFDYRAGTSPGTPNRIFFSDI-HFGNIQQI--- 2268
Query: 4908 SNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIA---VCDMR-GRFNR---IL 4750
N + R+ ++G+A +Y+T I V R G F R I
Sbjct: 2269 -NDDGSRRITIVENVGSVEGLAYHRGWDTLYWTSYTTSTITRHTVDQTRPGAFERETVIT 2327
Query: 4749 LKGTPLNDPRAIVLDPLQALVFWTDWGAS-AHIGRMNMDGSNEQVILQDRTIRWPNALAV 4573
+ G + PRA VLD Q L+FWT+W I R + G+N +++ + IR PN LA+
Sbjct: 2328 MSGD--DHPRAFVLDECQNLMFWTNWNEQHPSIMRAALSGANVLTLIE-KDIRTPNGLAI 2384
Query: 4572 DAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIER 4393
D A++LYF DA D I C YDGS R ++L+ H F LAV+ ++++W+DW ++R
Sbjct: 2385 DHRAEKLYFSDATLDKIERCEYDGSHRYVILKSEPVHPFGLAVYGEHIFWTDWVRRAVQR 2444
Query: 4392 VHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCS-QPARCDNLCIPANTP 4216
+K G+N K+L D +PMG V S PC C +LC
Sbjct: 2445 ANKHVGSNMKLLRVDIPQQPMGIIAVANDTNS-----CELSPCRINNGGCQDLC------ 2493
Query: 4215 DLTTSSDNFTCMCAQGFRSEG----RSCVSECKPNDFVCTKTYKCISSWWRXXXXXXXXX 4048
L T + C C G + R+ S C+ D +CI+
Sbjct: 2494 -LLTHQGHVNCSCRGGRILQDDLTCRAVNSSCRAQDEFECANGECIN----------FSL 2542
Query: 4047 XXXXGYFVEGVCPPFPCIAGQFVCGRT-AQNATAQCLYASKLCDGVKDCSGGDDEEPAFC 3871
+ P C +T Q + +C+ C+G DC G DE P C
Sbjct: 2543 TCDGVPHCKDKSDEKPSYCNSRRCKKTFRQCSNGRCVSNMLWCNGADDCGDGSDEIP--C 2600
Query: 3870 ENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCKPDFFACFNGTAI-- 3697
C +F+C D CI +S C++ DC+D SDE+NC T C F G
Sbjct: 2601 NKTACGVGEFRCRD-GTCIGNSSRCNQFVDCEDASDEMNCSATDCSSYFRLGVKGVLFQP 2659
Query: 3696 ----SKCIPKEFYCDGEDDCPEGQDEPDSCFGI--GECTHEQFQCTSGKCIPKRRQCDGT 3535
S C + CDG +DC + DE D C G+ C F C SG+CIP CD
Sbjct: 2660 CERTSLCYAPSWVCDGANDCGDYSDERD-CPGVKRPRCPLNYFACPSGRCIPMSWTCDKE 2718
Query: 3534 LDCRDGSDEKGCKKECA---IVCDN-SCVHADDLCDGKKKCNDGSDE----DEEACVIKQ 3379
DC G DE C K C+ C N C+ LCDG C DGSDE + + C
Sbjct: 2719 DDCEHGEDETHCNKFCSEAQFECQNHRCISKQWLCDGSDDCGDGSDEAAHCEGKTCGPSS 2778
Query: 3378 LLEKENRKC--GGFACDGIVDCEDGSDE---------KGCPDLECHLASN----KSLICD 3244
C + CDG DC DG+DE C D E + K +CD
Sbjct: 2779 FSCPGTHVCVPERWLCDGDKDCADGADESIAAGCLYNSTCDDREFMCQNRQCIPKHFVCD 2838
Query: 3243 GTIDCSSGKDEN-NCH--NNGESNFFQCS---MQTIKEWQVCDGRWDCADGLDESPE--M 3088
DC+ G DE+ C G S F+C+ + ++W+ CDG DC D DE+P+
Sbjct: 2839 HDRDCADGSDESPECEYPTCGPSE-FRCANGRCLSSRQWE-CDGENDCHDQSDEAPKNPH 2896
Query: 3087 CASRKARCFRIG-YCDDKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKGKYRCTNGR 2911
C S + +C + +C+ LC+G DC D SDE H + K +
Sbjct: 2897 CTSPEHKCNASSQFLCSSGRCV-AEALLCNGQDDCGDSSDERGCHINECLSRKLSGCSQD 2955
Query: 2910 CIDV----SARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYART 2743
C D+ R EC C+Q+C + + + +C C GYA
Sbjct: 2956 CEDLKIGFKCRCRPGFRLKDDGRTCADVDECSTTFPCSQRC-INTHGSYKCLCVEGYAPR 3014
Query: 2742 KNDENECEPLSKSAEMFITNGNRLHL--MSLENSQVSVLRPVFNIKMNLIPGGIDFGYDV 2569
D + C+ ++ E F+ NR +L ++L+ S ++L+ N + +DF Y
Sbjct: 3015 GGDPHSCKAVT-DEEPFLIFANRYYLRKLNLDGSNYTLLKQGLNNAV-----ALDFDY-- 3066
Query: 2568 FRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGL-----ITYDFMHNNVYFTES 2404
R ++Y + IR L GS + GL + D++ N+Y+ +
Sbjct: 3067 -REQMIYWTDVTTQGSMIRRMH----LNGSNVQVLHRTGLSNPDGLAVDWVGGNLYWCDK 3121
Query: 2403 SEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRIL 2224
I V+K L+ + +L VD ++WT I
Sbjct: 3122 GRD----------TIEVSKLNGAYRTVLVSSGLREPRALVVDVQNGYLYWTDWGDHSLIG 3171
Query: 2223 SANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDG 2044
+DG +V+ I P + LD+ ER+YW D + IE S DG
Sbjct: 3172 RIGMDG-----------SSRSVIVDTKITWPNGLTLDYVTERIYWADAREDYIEFASLDG 3220
Query: 2043 RDRRTVRKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGKTNKYV----------- 1900
+R V ++ + + Y+Y SI+R HK TG TNK +
Sbjct: 3221 SNRHVVLSQDIPHI-FALTLFEDYVYWTDWETKSINRAHKTTG-TNKTLLISTLHRPMDL 3278
Query: 1899 ---QKIRE--------------------VSPRIQIRVAHP--------AKHTVSHITHQK 1813
+R+ +SP + A P + VS+ T +
Sbjct: 3279 HVFHALRQPDVPNHPCKVNNGGCSNLCLLSPGGGHKCACPTNFYLGSDGRTCVSNCTASQ 3338
Query: 1812 NPCQSDYC-PSNTVCVPDQDKNGIL-----IPKCLCGPGRFFEVSTKKCMQLREKDQEAS 1651
C++D C P C + D P+ C PG+ F+ ST C A
Sbjct: 3339 FVCKNDKCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQ-FQCSTGIC------TNPAF 3391
Query: 1650 QC-GDYFCYNNAGCSPQKTCVCPPGFYGRQCEINEC---------SETCWNGE------- 1522
C GD C +N+ + VC P + + N C + C +GE
Sbjct: 3392 ICDGDNDCQDNSDEANCDIHVCLPSQF-KCTNTNRCIPGIFRCNGQDNCGDGEDERDCPE 3450
Query: 1521 -TCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSYSFC 1345
TCA +F + C P + N C +C + C DE C+ C
Sbjct: 3451 VTCAPNQFQCSITKRC-IPRVWVCD--RDNDCVDGSDEPANCTQMTCGVDEFRCKDSGRC 3507
Query: 1344 ---------ECDKGWTGPHCRHKADAKVCYGH---CFSGGACDGEGPLNLRCSCGDGLTG 1201
E D G + + D + C + C + G + CGD
Sbjct: 3508 IPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDE 3567
Query: 1200 NRCQ---------NCVGHECLNGGF-------CSYANSNRS-LPHC-----ICPSGF--- 1096
C +C C+ G + C+ + + P C C SG
Sbjct: 3568 ESCTPRPCSESEFSCANGRCIAGRWKCDGDHDCADGSDEKDCTPRCDMDQFQCKSGHCIP 3627
Query: 1095 ------TGDHCEEYLCKDACPFGSKCTYDITKPMDPITCS---CEQNA--AAHNTDCSPI 949
C + ++AC G + T P+D C+ C+ A DC
Sbjct: 3628 LRWRCDADADCMDGSDEEACGTGVR-----TCPLDEFQCNNTLCKPLAWKCDGEDDCGDN 3682
Query: 948 CQKQPNWCHNGGRCLDTPGYPGKCK----CLPRFAGPRCDVPVQCDDYCTNNSKCTITNG 781
+ P C R + P P +CK CL + G +CD C D T+ C
Sbjct: 3683 SDENPEEC---ARFVCPPNRPFRCKNDRVCL--WIGRQCDGTDNCGD-GTDEEDCEPPTA 3736
Query: 780 THFECDCKPGF---------KGLRCEQETKCSECSNEAKCIKKPSGTVICQCPQGLGGEY 628
C K F LRC C + S+E C P
Sbjct: 3737 HTTHCKDKKEFLCRNQRCLSSSLRCNMFDDCGDGSDEEDCSIDP---------------- 3780
Query: 627 CEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSSNACE--NFCLHDG 454
K+T+ + + C + C++ + +A C C GF + C+ N CL G
Sbjct: 3781 --KLTSCATNASICGDEARCVRTEKAA-----YCACRSGFH-TVPGQPGCQDINECLRFG 3832
Query: 453 NCTL---DEYFEPQCECYQAFI--GDRCQYRIHQHAVIFSDDDS 337
C+ + C C + F+ + C+ ++ V++ DD+
Sbjct: 3833 TCSQLCNNTKGGHLCSCARNFMKTHNTCKAEGSEYQVLYIADDN 3876
Score = 335 bits (858), Expect = 1e-89
Identities = 314/1244 (25%), Positives = 496/1244 (39%), Gaps = 89/1244 (7%)
Frame = -1
Query: 5259 HLSPYDKKTCLRSPSCPK------ANCSHFCI-DRRDVGHQCFCAPGYILSENQKDCRRN 5101
H+ ++ +RS +C CS C+ C C G+ L + K C++
Sbjct: 463 HIYHQRRQPRVRSHACENDQYGKPGGCSDICLLANSHKARTCRCRSGFSLGSDGKSCKKP 522
Query: 5100 DTIEAEILMVYGHRLK--LFTIDGHAKAT-----LLSNLTNGVALDYDVKSDLVYWTDVA 4942
E E+ +VYG + +D AK + NL N ALD+ ++ +Y+ D
Sbjct: 523 ---EHELFLVYGKGRPGIIRGMDMGAKVPDEHMIPIENLMNPRALDFHAETGFIYFADTT 579
Query: 4941 HDGNKAGITSMSNQPNTYR-VINSLPTKGIDGIAVDWLGRNIYYTD---RNHDAIAVCDM 4774
+ + T R I ++G+AVDW+G N+Y+TD + ++A +
Sbjct: 580 -----SYLIGRQKIDGTERETILKDGIHNVEGVAVDWMGDNLYWTDDGPKKTISVARLEK 634
Query: 4773 RGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDW------GASAHIGRMNMDGSNEQVIL 4612
+ + L++G + PRAIV+DPL ++WTDW + R MDGS+ + +
Sbjct: 635 AAQTRKTLIEGK-MTHPRAIVVDPLNGWMYWTDWEEDPKDSRRGRLERAWMDGSHRDIFV 693
Query: 4611 QDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRG-SVRHIFALAVFED 4435
+T+ WPN L++D PA RLY+ DA D I + +G+ R++V G + H F L +
Sbjct: 694 TSKTVLWPNGLSLDIPAGRLYWVDAFYDRIETILLNGTDRKIVYEGPELNHAFGLCHHGN 753
Query: 4434 YVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKI--VHPSLQSMGSLKTARHPCS 4261
Y++W+++ + ++ R+ + G + + RP F+I Q +G+ K
Sbjct: 754 YLFWTEYRSGSVYRLERGVGGAPPTVTLLRSERPPIFEIRMYDAQQQQVGTNKCR----V 809
Query: 4260 QPARCDNLCIPANTPDLTTSSDNFTCMCAQGFRSEGRSCVS--------ECKPNDFVCTK 4105
C +LC+ T S C Q ++G +C++ +C+P +F C
Sbjct: 810 NNGGCSSLCL------ATPGSRQCACAEDQVLDADGVTCLANPSYVPPPQCQPGEFACAN 863
Query: 4104 TYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKL 3925
+ +CI W+
Sbjct: 864 S-RCIQERWK-------------------------------------------------- 872
Query: 3924 CDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELN--C 3751
CDG DC DE PA C C +FKC + +CIP +CD + DC + DE N C
Sbjct: 873 CDGDNDCLDNSDEAPALCHQHTCPSDRFKC-ENNRCIPNRWLCDGDNDCGNSEDESNATC 931
Query: 3750 EITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSG 3571
+C P+ F+C +G +CIP + CD +DDC + DE SC QF C +G
Sbjct: 932 SARTCPPNQFSCASG----RCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNG 987
Query: 3570 KCIPKRRQCDGTLDCRDGSDEKGCKKECA---IVCDNS-CVHADDLCDGKKKCNDGSDED 3403
+CI +CD DC D SDE GC C+ C++ C+ CDG C D SDE
Sbjct: 988 RCININWRCDNDNDCGDNSDEAGCSHSCSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDET 1047
Query: 3402 EEACVIKQLLEKENRKCGG------------------FACDGIVDCEDGSDEKGCPDL-- 3283
C + R GG + CDG DC D SDEK C +
Sbjct: 1048 HANCT-----NQATRPPGGCHTDEFQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTH 1102
Query: 3282 -----------ECHLASNKSLICDGTIDCSSGKDENNCHNNG-ESNFFQCSMQT---IKE 3148
+ +K+ +CDG DC DE NC + C+ T +
Sbjct: 1103 VCDPSVKFGCKDSARCISKAWVCDGDNDCEDNSDEENCESLACRPPSHPCANNTSVCLPP 1162
Query: 3147 WQVCDGRWDCADGLDESP--EMCASRKARCFRIGYCDDKKQCLDVSTALCDGI-RDCFDG 2977
++CDG DC DG DE + C+ C + S A +GI C G
Sbjct: 1163 DKLCDGNDDCGDGSDEGELCDQCSLNNGGCSH-----------NCSVAPGEGIVCSCPLG 1211
Query: 2976 SDENPIHCKDMCKGKYRCTNGRCIDVSARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCW 2797
+ P N C + C C+QKC
Sbjct: 1212 MELGP-------------DNHTC--------------------QIQSYCAKHLKCSQKCD 1238
Query: 2796 MAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFI-TNGNRLHLMSLENSQVSVLRPVF 2620
+ +C C G+ + D C L I +N + + + L SVL P
Sbjct: 1239 QN-KFSVKCSCYEGWV-LEPDGESCRSLDPFKPFIIFSNRHEIRRIDLHKGDYSVLVPGL 1296
Query: 2619 NIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGLIT- 2443
N I +DF + +Y + ++ R K +G + S+ E GL T
Sbjct: 1297 R---NTI--ALDFH---LSQSALYWTDVVEDKI-YRGKLLDNGALTSF-EVVIQYGLATP 1346
Query: 2442 ----YDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDP 2275
D++ N+Y+ ES+ I VAK T TL+ ++A+DP
Sbjct: 1347 EGLAVDWIAGNIYWVESNLD----------QIEVAKLDGTLRTTLLAGDIEHPRAIALDP 1396
Query: 2274 IKRLIFWTT-SAPVPRILSANLDGKPIAQPFK-TGSQPHKALVERNIFEPTSMVLDFSNE 2101
++FWT A +PRI +A++ G + TGS P + +D+ +
Sbjct: 1397 RDGILFWTDWDASLPRIEAASMSGAGRRTVHRETGSGGW----------PNGLTVDYLEK 1446
Query: 2100 RLYWIDVLKRTIETVSFDGRDRRTV-RKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHK 1927
R+ WID I + +DG V R E P + + GG +Y R ++ + +K
Sbjct: 1447 RILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYGGEVYWTDWRTNTLAKANK 1506
Query: 1926 FTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSD 1795
+TG VQ R + ++V HP++ ++ NPC+++
Sbjct: 1507 WTGHNVTVVQ--RTNTQPFDLQVYHPSRQPMA-----PNPCEAN 1543
Score = 204 bits (520), Expect = 2e-50
Identities = 150/518 (28%), Positives = 241/518 (45%), Gaps = 26/518 (5%)
Frame = -1
Query: 5619 RQCKPNEWMC-DSGQCIDSGRLCDASVDCVDGSDEWVEICSLSEPPRRGC-PSGWSCLLT 5446
+ C P ++ C D CI G CD DC DGSDE EIC S+ R C P+ +CL
Sbjct: 25 KTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQR--CQPNEHNCL-- 80
Query: 5445 NGTIGCLQEQQLCDGRRDCMSGIDE--QCDNPQGNCSSTRNSCDQTWNCQRHAGFESCSC 5272
GT C+ +LC+G +DCM G DE C QGNCS R C +C +C C
Sbjct: 81 -GTELCVPMSRLCNGVQDCMDGSDEGPHCRELQGNCS--RLGCQH--HCVPTLDGPTCYC 135
Query: 5271 DDGYHLSPYDKKTCLRSPSCPK-ANCSHFCIDRRDVGHQCFCAPGYILSENQKDCR-RND 5098
+ + L D KTC C CS C + D C C GY+L + + C+ +N+
Sbjct: 136 NSSFQLQA-DGKTCKDFDECSVYGTCSQLCTNT-DGSFICGCVEGYLLQPDNRSCKAKNE 193
Query: 5097 TIEAEILMVYGHRLKLFT--IDGHAKATLLSNLTNGV-ALDYDVKSDLVYWTDVAHDGNK 4927
++ +++ + + + G +T+ T A+D+ ++ V W V +
Sbjct: 194 PVDRPPVLLIANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWVHVGDSAAQ 253
Query: 4926 -----AGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRF 4762
A + + + + + SL ++ +A+DWL N Y+ D D I VC+ G
Sbjct: 254 TQLKCARMPGLKGFVDEHTINISLSLHHVEQMAIDWLTGNFYFVDDIDDRIFVCNRNGD- 312
Query: 4761 NRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNA 4582
+ L L +P+ I LDP VF+TD+G + R +MDG N + L D I +P+
Sbjct: 313 TCVTLLDLELYNPKGIALDPAMGKVFFTDYGQIPKVERCDMDGQN-RTKLVDSKIVFPHG 371
Query: 4581 LAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRG-SVRHIFALAVFEDYVYWSDWHNH 4405
+ +D ++ +Y+ DA+ DYI +Y+G R+ +++G + H++ L VFE+Y+Y ++ N
Sbjct: 372 ITLDLVSRLVYWADAYLDYIEVVDYEGKGRQTIIQGILIEHLYGLTVFENYLYATNSDNA 431
Query: 4404 TIERVHKITGTNR----KVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPC-----SQPA 4252
++ + NR + + + + I H Q + H C +P
Sbjct: 432 NAQQKTSVIRVNRFNSTEYQVVTRVDKGGALHIYHQRRQP----RVRSHACENDQYGKPG 487
Query: 4251 RCDNLCIPANTPDLTTSSDNFTCMCAQGFR--SEGRSC 4144
C ++C+ AN S TC C GF S+G+SC
Sbjct: 488 GCSDICLLAN------SHKARTCRCRSGFSLGSDGKSC 519
Score = 176 bits (445), Expect = 9e-42
Identities = 104/277 (37%), Positives = 134/277 (47%), Gaps = 10/277 (3%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADES-NC---TCNE-NEFR 6409
+DE CS R C P F+C +G CIP C+ +DC + +DES +C TC +F
Sbjct: 924 EDESNATCSARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQFT 983
Query: 6408 CQSGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKC 6229
C +G CI RC++ DC D SDE GC +CS+ C + +CI W C
Sbjct: 984 CNNGRCININWRCDNDNDCGDNSDEAGCS-HSCSSTQ-------FKC-NSGRCIPEHWTC 1034
Query: 6228 DGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCA 6049
DG NDC D SDE + T + P C +F C C+P W+CDG DC
Sbjct: 1035 DGDNDCGDYSDE----THANCTNQATRPPGGCHT-DEFQCRLDGLCIPLRWRCDGDTDCM 1089
Query: 6048 DGSDEKNCD--AKKC-TSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGG 5878
D SDEK+C+ C S +F C+ S +CI CDG DC D DE CE+
Sbjct: 1090 DSSDEKSCEGVTHVCDPSVKFGCKDSARCISKAWVCDGDNDCEDNSDEENCESLACRPPS 1149
Query: 5877 NATFRCTNHR--CIPMAWRCDGTDDCMDNAKSLGSDE 5773
+ C N+ C+P CDG DDC D GSDE
Sbjct: 1150 HP---CANNTSVCLPPDKLCDGNDDCGD-----GSDE 1178
Score = 155 bits (391), Expect = 2e-35
Identities = 110/387 (28%), Positives = 180/387 (46%), Gaps = 15/387 (3%)
Frame = -1
Query: 5259 HLSPYDKKTCLRSP-----SCPKANCSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDT 5095
H+ YD+ L S +CS C+ + C C GY L Q+ C +
Sbjct: 1832 HMKVYDESIQLDHKGTNPCSVNNGDCSQLCLPTSETTRSCMCTAGYSLRSGQQAC---EG 1888
Query: 5094 IEAEILMVYGHRLKLFTIDGHAKATLL---SNLTNGVALDYDVKSDLVYWTDVAHDGNKA 4924
+ + +L ++ +D + K+ L S + V +D+ ++D +YW D+
Sbjct: 1889 VGSFLLYSVHEGIRGIPLDPNDKSDALVPVSGTSLAVGIDFHAENDTIYWVDM------- 1941
Query: 4923 GITSMSNQPNTYRVINSLPTKGI---DGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRI 4753
G++++S + T GI +GIAVDW+ NIY+TD+ D I V + G F +
Sbjct: 1942 GLSTISRAKRDQTWREDVVTNGIGRVEGIAVDWIAGNIYWTDQGFDVIEVARLNGSFRYV 2001
Query: 4752 LLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAV 4573
++ L+ PRAI + P + +FWT+WG I R +DG+ E+V+L + +I WPN ++V
Sbjct: 2002 VI-SQGLDKPRAITVHPEKGYLFWTEWGQYPRIERSRLDGT-ERVVLVNVSISWPNGISV 2059
Query: 4572 DAPAQRLYFGDAHRDYIASCNYD-GSKRRMVLRGSVRHIFALAVFEDYVYWSD--WHNHT 4402
D +LY+ DA D I + + G R +VL + +F+++VFED++YWSD N +
Sbjct: 2060 DYQDGKLYWCDARTDKIERIDLETGENREVVLSSNNMDMFSVSVFEDFIYWSDRTHANGS 2119
Query: 4401 IERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDNLCIPAN 4222
I+R K T+ L + K+ + Q ++ + C LC
Sbjct: 2120 IKRGSKDNATDSVPLRTGIGVQLKDIKVFNRDRQKGTNVCAVAN-----GGCQQLC---- 2170
Query: 4221 TPDLTTSSDNFTCMCAQGFRSE-GRSC 4144
L C CA G +E G SC
Sbjct: 2171 ---LYRGRGQRACACAHGMLAEDGASC 2194
Score = 127 bits (320), Expect = 3e-27
Identities = 93/341 (27%), Positives = 127/341 (36%)
Frame = -1
Query: 1173 ECLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCS 994
+C NGG C + N+ R P C C +TGD CE C +
Sbjct: 4203 QCFNGGSC-FLNARRQ-PKCRCQPRYTGDKCELDQCWEH--------------------- 4239
Query: 993 CEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYC 814
C NGG C +P C+C F GP+C V C YC
Sbjct: 4240 ----------------------CRNGGTCAASPSGMPTCRCPTGFTGPKCTQQV-CAGYC 4276
Query: 813 TNNSKCTITNGTHFECDCKPGFKGLRCEQETKCSECSNEAKCIKKPSGTVICQCPQGLGG 634
NNS CT+ G +C C PGF G RC+ C N C G+ C+C G
Sbjct: 4277 ANNSTCTVNQGNQPQCRCLPGFLGDRCQYRQCSGYCENFGTCQMAADGSRQCRCTAYFEG 4336
Query: 633 EYCEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCLHDG 454
CE + C + G C+ S + TC C+ G C + C C + G
Sbjct: 4337 SRCEVNKCSRCLE------GACVVNKQSGD---VTCNCTDGRVAPSCLT--CVGHCSNGG 4385
Query: 453 NCTLDEYFEPQCECYQAFIGDRCQYRIHQHAVIFSDDDSGWIKSFXXXXXXXXXXXXXXX 274
+CT++ P+C+C G RC+ +H +FS G I S
Sbjct: 4386 SCTMNSKMMPECQCPPHMTGPRCE----EH--VFSQQQPGHIASILIPLLLLLLLVLVAG 4439
Query: 273 IFANRSNRFAVFRQFRHNPLQNQGAPVDQFSNPAYLIDEGG 151
+ R + F+H + N GA + NP Y + EGG
Sbjct: 4440 VVFWYKRRVQGAKGFQHQRMTN-GAMNVEIGNPTYKMYEGG 4479
Score = 127 bits (318), Expect = 5e-27
Identities = 97/365 (26%), Positives = 164/365 (44%), Gaps = 13/365 (3%)
Frame = -1
Query: 5199 CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAK-- 5026
CSH C+ + C C L ++ C E + ++Y ++++ +D A
Sbjct: 1549 CSHLCLINYNRTVSCACPHLMKLHKDNTTC-----YEFKKFLLYARQMEIRGVDLDAPYY 1603
Query: 5025 ----ATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKG 4858
+ + ++ N LDYD + VYW+DV K + + + S
Sbjct: 1604 NYIISFTVPDIDNVTVLDYDAREQRVYWSDVRTQAIKRAFINGTG----VETVVSADLPN 1659
Query: 4857 IDGIAVDWLGRNIYYT--DRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVF 4684
G+AVDW+ RN+++T D N I V + G F +++G L P +V+ PL+ ++
Sbjct: 1660 AHGLAVDWVSRNLFWTSYDTNKKQINVARLDGSFKNAVVQG--LEQPHGLVVHPLRGKLY 1717
Query: 4683 WTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYD 4504
WTD +I NMDGSN ++ + + P LA+D P +LY+ + I CN D
Sbjct: 1718 WTD---GDNISMANMDGSNRTLLFSGQ--KGPVGLAIDFPESKLYWISSGNHTINRCNLD 1772
Query: 4503 GSKRRMV--LRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPM 4330
GS ++ +R + ALA+ D ++W+D + + K G+ V++++ M
Sbjct: 1773 GSGLEVIDAMRSQLGKATALAIMGDKLWWADQVSEKMGTCSKADGSG-SVVLRNSTTLVM 1831
Query: 4329 GFKIVHPSLQSMGSLKTARHPCS-QPARCDNLCIPANTPDLTTSSDNFTCMCAQGF--RS 4159
K+ S+Q +PCS C LC+P TS +CMC G+ RS
Sbjct: 1832 HMKVYDESIQLD---HKGTNPCSVNNGDCSQLCLP-------TSETTRSCMCTAGYSLRS 1881
Query: 4158 EGRSC 4144
++C
Sbjct: 1882 GQQAC 1886
Score = 121 bits (304), Expect = 2e-25
Identities = 92/340 (27%), Positives = 117/340 (34%), Gaps = 2/340 (0%)
Frame = -1
Query: 1497 STTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSYSFCECDKGWTGP 1318
S + VC CP+ + G+C VP P P C
Sbjct: 4163 SPSGPVCTCPNGKRLDN-------------GTCVPVPSPTPPPDAPRPGTCNLQ------ 4203
Query: 1317 HCRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQ--NCVGHECLNGGFCSY 1144
CF+GG+C +C C TG++C+ C H C NGG C
Sbjct: 4204 --------------CFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCWEH-CRNGGTC-- 4246
Query: 1143 ANSNRSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCSCEQNAAAHNT 964
A S +P C CP+GFTG C + +C C S CT +
Sbjct: 4247 AASPSGMPTCRCPTGFTGPKCTQQVCAGYCANNSTCTVN--------------------- 4285
Query: 963 DCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSKCTITN 784
G +C+CLP F G RC QC YC N C +
Sbjct: 4286 ----------------------QGNQPQCRCLPGFLGDRCQYR-QCSGYCENFGTCQMAA 4322
Query: 783 GTHFECDCKPGFKGLRCEQETKCSECSNEAKCIKKPSGTVICQCPQGLGGEYCEKITATS 604
+C C F+G RCE KCS C A + K SG V C C G C +T
Sbjct: 4323 DGSRQCRCTAYFEGSRCE-VNKCSRCLEGACVVNKQSGDVTCNCTDGRVAPSC--LTCVG 4379
Query: 603 CHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSSN 484
C NGG C ++ P C C P G C +
Sbjct: 4380 ----HCSNGGSC----TMNSKMMPECQCPPHMTGPRCEEH 4411
Score = 118 bits (295), Expect = 2e-24
Identities = 113/465 (24%), Positives = 183/465 (39%), Gaps = 18/465 (3%)
Frame = -1
Query: 3153 KEWQVCDGRWDCADGLDESPEMCASRKA-RCFRIGY-CDDKKQCLDVSTALCDGIRDCFD 2980
K W+ CDG DC DG DE+PE+C KA RC + C + C+ +S LC+G++DC D
Sbjct: 43 KGWR-CDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTELCVPMSR-LCNGVQDCMD 100
Query: 2979 GSDENPIHCKDMCKGKYRC-TNGRCIDV----SARXXXXXXXXXXXXXXXXGAECHHFGV 2815
GSDE P HC+++ R C+ + EC +G
Sbjct: 101 GSDEGP-HCRELQGNCSRLGCQHHCVPTLDGPTCYCNSSFQLQADGKTCKDFDECSVYGT 159
Query: 2814 CAQKCWMAFNHTARCHCAPGYARTKNDENEC----EPLSKSAEMFITNGNRLHLMSLENS 2647
C+Q C + + C C GY + D C EP+ + + I N + L +
Sbjct: 160 CSQLCTNT-DGSFICGCVEGYL-LQPDNRSCKAKNEPVDRPPVLLIANSQNILATYLSGA 217
Query: 2646 QVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEE 2467
QVS + P + +DF Y T VG ++ ++ + GL G E
Sbjct: 218 QVSTITPTSTRQTT----AMDFSY-ANETVCWVHVGDSAAQTQLKCARMP-GLKGFVDEH 271
Query: 2466 ESTAGL-------ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNS 2308
L + D++ N YF + D I+V + TL+
Sbjct: 272 TINISLSLHHVEQMAIDWLTGNFYFVD----------DIDDRIFVCNRNGDTCVTLLDLE 321
Query: 2307 TGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPT 2128
+A+DP +F+T +P++ ++DG Q LV+ I P
Sbjct: 322 LYNPKGIALDPAMGKVFFTDYGQIPKVERCDMDG-----------QNRTKLVDSKIVFPH 370
Query: 2127 SMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITRQG 1948
+ LD + +YW D IE V ++G+ R+T+ + L + + V Y+Y
Sbjct: 371 GITLDLVSRLVYWADAYLDYIEVVDYEGKGRQTIIQGILIEHLYGLTVFENYLYATNSDN 430
Query: 1947 SIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQK 1813
+ + + N++ +V R+ K HI HQ+
Sbjct: 431 ANAQQKTSVIRVNRFNSTEYQVVTRVD-------KGGALHIYHQR 468
Score = 110 bits (274), Expect = 6e-22
Identities = 197/882 (22%), Positives = 318/882 (35%), Gaps = 69/882 (7%)
Frame = -1
Query: 2820 GVCAQKCWMAFNHTAR-CHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQ 2644
G C+ C +A +H AR C C G++ +D C+ + G + ++
Sbjct: 487 GGCSDICLLANSHKARTCRCRSGFS-LGSDGKSCKKPEHELFLVYGKGRPGIIRGMDMGA 545
Query: 2643 VSVLRPVFNIKMNLIPGGIDF----GYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSW 2476
+ I+ + P +DF G+ F T Y +G R DG+
Sbjct: 546 KVPDEHMIPIENLMNPRALDFHAETGFIYFADTTSYLIGRQKIDGTERETILKDGIHNVE 605
Query: 2475 GEEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTST--RTLIVNSTG 2302
G + D+M +N+Y+T+ + I VA+ + + +TLI
Sbjct: 606 G--------VAVDWMGDNLYWTDDGPKK---------TISVARLEKAAQTRKTLIEGKMT 648
Query: 2301 TINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSM 2122
++ VDP+ ++WT P+ + G+ + + + GS + + + P +
Sbjct: 649 HPRAIVVDPLNGWMYWTDWEEDPK---DSRRGR-LERAWMDGSHRDIFVTSKTVLWPNGL 704
Query: 2121 VLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT-RQGS 1945
LD RLYW+D IET+ +G DR+ V + + + G Y++ R GS
Sbjct: 705 SLDIPAGRLYWVDAFYDRIETILLNGTDRKIVYEGPELNHAFGLCHHGNYLFWTEYRSGS 764
Query: 1944 IHRMHKFTGKTNKYVQKIREVSPRI-QIRVAHPAKHTV-SHITHQKNPCQSDYC---PSN 1780
++R+ + G V +R P I +IR+ + V ++ N S C P +
Sbjct: 765 VYRLERGVGGAPPTVTLLRSERPPIFEIRMYDAQQQQVGTNKCRVNNGGCSSLCLATPGS 824
Query: 1779 TVCVPDQDK-----------NGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCGDYF 1633
C +D+ N +P C PG F + +C+Q R K GD
Sbjct: 825 RQCACAEDQVLDADGVTCLANPSYVPPPQCQPGE-FACANSRCIQERWKCD-----GDND 878
Query: 1632 CYNNAGCSPQ--KTCVCPPGFYGRQCEINECSETCW---NGETCAVQEFGSTTNVVCH-- 1474
C +N+ +P CP + +CE N C W C E +N C
Sbjct: 879 CLDNSDEAPALCHQHTCPSDRF--KCENNRCIPNRWLCDGDNDCGNSE--DESNATCSAR 934
Query: 1473 -CPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHKAD 1297
CP N Q SCA+ C + + C D+ +C R
Sbjct: 935 TCPPN--QFSCASGRCIPI--------SWTCDLDD---------DCGD-------RSDES 968
Query: 1296 AKVCYGHCF-------SGGACDGEGPLNLRC----SCGDGLTGNRCQNCVGHECLNGGFC 1150
A Y CF + G C +N RC CGD C H C + F
Sbjct: 969 ASCAYPTCFPLTQFTCNNGRCIN---INWRCDNDNDCGDNSDEAGC----SHSCSSTQF- 1020
Query: 1149 SYANSNRSLP-HCICP-SGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCSCEQNAA 976
NS R +P H C GD+ +E + CT T+P P C ++
Sbjct: 1021 -KCNSGRCIPEHWTCDGDNDCGDYSDE--------THANCTNQATRP--PGGCHTDEFQC 1069
Query: 975 AHNTDCSPICQKQPNW-CHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSK 799
+ C P+ W C C+D+ C+ + P V C D SK
Sbjct: 1070 RLDGLCIPL-----RWRCDGDTDCMDSSD-EKSCEGVTHVCDP--SVKFGCKDSARCISK 1121
Query: 798 CTITNGTHFECDCKPGFKGLRCEQETKCSECSNEAKCIKKPSGTVICQCPQGL--GGEYC 625
+ +G + DC+ CE C S+ + T +C P L G + C
Sbjct: 1122 AWVCDGDN---DCEDNSDEENCE-SLACRPPSHPC-----ANNTSVCLPPDKLCDGNDDC 1172
Query: 624 --EKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCS----------SNA 481
C Q NGG S C +PG +G++CS ++
Sbjct: 1173 GDGSDEGELCDQCSLNNGG-----------CSHNCSVAPG-EGIVCSCPLGMELGPDNHT 1220
Query: 480 C--ENFCLHDGNCTL---DEYFEPQCECYQAFI----GDRCQ 382
C +++C C+ F +C CY+ ++ G+ C+
Sbjct: 1221 CQIQSYCAKHLKCSQKCDQNKFSVKCSCYEGWVLEPDGESCR 1262
Score = 88.2 bits (217), Expect = 2e-15
Identities = 47/136 (34%), Positives = 70/136 (50%), Gaps = 5/136 (3%)
Frame = -1
Query: 6156 SVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADGSDE-----KNCDAKKCTSFEFS 5992
++ AP++C K QFAC TC+ K W+CDG+ DC DGSDE A++C E +
Sbjct: 20 AIDAPKTCSPK-QFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHN 78
Query: 5991 CESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNATFRCTNHRCIPMAWRCDGTD 5812
C ++ C+P+ + C+G +DC DG DE C GN + H C+P DG
Sbjct: 79 CLGTELCVPMSRLCNGVQDCMDGSDE---GPHCRELQGNCSRLGCQHHCVP---TLDGPT 132
Query: 5811 DCMDNAKSLGSDEVDC 5764
+++ L +D C
Sbjct: 133 CYCNSSFQLQADGKTC 148
Score = 70.9 bits (172), Expect = 4e-10
Identities = 59/184 (32%), Positives = 78/184 (42%), Gaps = 15/184 (8%)
Frame = -1
Query: 3858 CTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDEL-----NCEITSCKPDFFACFNGTAIS 3694
C+ QF C D+ CI CD E+DC DGSDE + C+P+ C GT +
Sbjct: 27 CSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCL-GTEL- 84
Query: 3693 KCIPKEFYCDGEDDCPEGQDEPDSCFGI-GECTHEQFQCTSGKCIPKRRQCDG-TLDCRD 3520
C+P C+G DC +G DE C + G C+ Q C+P DG T C
Sbjct: 85 -CVPMSRLCNGVQDCMDGSDEGPHCRELQGNCSRLGCQ---HHCVP---TLDGPTCYCNS 137
Query: 3519 G----SDEKGCK--KECAI--VCDNSCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKE 3364
+D K CK EC++ C C + DG C CV LL+ +
Sbjct: 138 SFQLQADGKTCKDFDECSVYGTCSQLCTNT----DGSFIC---------GCVEGYLLQPD 184
Query: 3363 NRKC 3352
NR C
Sbjct: 185 NRSC 188
Score = 65.9 bits (159), Expect = 1e-08
Identities = 51/180 (28%), Positives = 71/180 (39%), Gaps = 4/180 (2%)
Frame = -1
Query: 1794 YCPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCGDYFCYNNAG 1615
YC +N+ C +Q P+C C PG + +C + QC Y C N
Sbjct: 4275 YCANNSTCTVNQGNQ----PQCRCLPGFLGD----RC--------QYRQCSGY-CENFGT 4317
Query: 1614 CSP----QKTCVCPPGFYGRQCEINECSETCWNGETCAVQEFGSTTNVVCHCPSNYTQSS 1447
C + C C F G +CE+N+CS C G C V + + +V C+C S
Sbjct: 4318 CQMAADGSRQCRCTAYFEGSRCEVNKCSR-CLEG-ACVVNK--QSGDVTCNCTDGRVAPS 4373
Query: 1446 CATNVCEGVCGPRGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHKADAKVCYGHCFS 1267
C T C G C GSC + + C+C TGP C ++ GH S
Sbjct: 4374 CLT--CVGHCSNGGSCTM--------NSKMMPECQCPPHMTGPRCEEHVFSQQQPGHIAS 4423
Score = 65.1 bits (157), Expect = 2e-08
Identities = 76/306 (24%), Positives = 120/306 (38%), Gaps = 8/306 (2%)
Frame = -1
Query: 2820 GVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQV 2641
G C+Q C T C C GY+ ++ + CE + + G R + N +
Sbjct: 1855 GDCSQLCLPTSETTRSCMCTAGYS-LRSGQQACEGVGSFLLYSVHEGIRGIPLD-PNDKS 1912
Query: 2640 SVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEES 2461
L PV + + GIDF + +Y V +G S + R+K+ +W E+
Sbjct: 1913 DALVPVSGTSLAV---GIDFHAE---NDTIYWVDMGLSTIS-RAKRDQ-----TWREDVV 1960
Query: 2460 TAGL-----ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTI 2296
T G+ I D++ N+Y+T+ FD I VA+ + +I
Sbjct: 1961 TNGIGRVEGIAVDWIAGNIYWTDQG-------FDV---IEVARLNGSFRYVVISQGLDKP 2010
Query: 2295 NSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVL 2116
++ V P K +FWT PRI + LDG LV +I P + +
Sbjct: 2011 RAITVHPEKGYLFWTEWGQYPRIERSRLDG-----------TERVVLVNVSISWPNGISV 2059
Query: 2115 DFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITR---QGS 1945
D+ + +LYW D IE + + + R V ++ V +IY R GS
Sbjct: 2060 DYQDGKLYWCDARTDKIERIDLETGENREVVLSSNNMDMFSVSVFEDFIYWSDRTHANGS 2119
Query: 1944 IHRMHK 1927
I R K
Sbjct: 2120 IKRGSK 2125
Score = 63.2 bits (152), Expect = 8e-08
Identities = 60/224 (26%), Positives = 90/224 (39%), Gaps = 20/224 (8%)
Frame = -1
Query: 5820 GTDDCMDNAKSLGSDEVDCAAGRTSFHVPSR--CADETCVVACELTAVLCDGIQDCSDGF 5647
G +C + D++ C A +S CA+ C+ ++ CDG+ C D
Sbjct: 2499 GHVNCSCRGGRILQDDLTCRAVNSSCRAQDEFECANGECINF----SLTCDGVPHCKDKS 2554
Query: 5646 DEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASVDCVDGSDEWVEICSLSEPPRRGCPS 5467
DEK R+CK C +G+C+ + C+ + DC DGSDE C+ + C
Sbjct: 2555 DEKPSYCNSRRCKKTFRQCSNGRCVSNMLWCNGADDCGDGSDEIP--CN-----KTACGV 2607
Query: 5466 G-WSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSSTRNS------------ 5326
G + C +GT C+ C+ DC DE NCS+T S
Sbjct: 2608 GEFRC--RDGT--CIGNSSRCNQFVDCEDASDEM------NCSATDCSSYFRLGVKGVLF 2657
Query: 5325 --CDQTWNCQRHAGFESCSCDDGYHLSPY-DKKTC--LRSPSCP 5209
C++T C S CD Y D++ C ++ P CP
Sbjct: 2658 QPCERTSLCYA----PSWVCDGANDCGDYSDERDCPGVKRPRCP 2697
Score = 58.5 bits (140), Expect = 2e-06
Identities = 35/112 (31%), Positives = 42/112 (37%), Gaps = 10/112 (8%)
Frame = -1
Query: 6270 CATTSQCIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAK-------TQFA 6112
C CI W+CDG DC DGSDE AP C +
Sbjct: 34 CRDQITCISKGWRCDGERDCPDGSDE---------------APEICPQSKAQRCQPNEHN 78
Query: 6111 CLATRTCMPKHWQCDGQPDCADGSDEKNCDAKKCTSFEFSCE---SSKKCIP 5965
CL T C+P C+G DC DGSDE C + +C C+P
Sbjct: 79 CLGTELCVPMSRLCNGVQDCMDGSDE----GPHCRELQGNCSRLGCQHHCVP 126
Score = 55.1 bits (131), Expect = 2e-05
Identities = 49/172 (28%), Positives = 61/172 (34%), Gaps = 5/172 (2%)
Frame = -1
Query: 6432 TCNENEFRCQSG-ACIPSKARCNHMQDCNDASDEIG--CPFRNCSAL--NEFGMTGLINC 6268
TC+ +F C+ CI RC+ +DC D SDE CP NE NC
Sbjct: 26 TCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEH------NC 79
Query: 6267 ATTSQCIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCM 6088
T C+ S C+G DC DGSDE E + Q C+ T
Sbjct: 80 LGTELCVPMSRLCNGVQDCMDGSDEGPHCRELQGNCSRLGC--------QHHCVPT---- 127
Query: 6087 PKHWQCDGQPDCADGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDC 5932
DG + S + D K C F+ C C L DG C
Sbjct: 128 -----LDGPTCYCNSSFQLQADGKTCKDFD-ECSVYGTCSQLCTNTDGSFIC 173
Score = 51.6 bits (122), Expect = 3e-04
Identities = 58/269 (21%), Positives = 99/269 (36%), Gaps = 10/269 (3%)
Frame = -1
Query: 2820 GVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQV 2641
G C+ C + +N T C C P + D C K L+ +E V
Sbjct: 1547 GPCSHLCLINYNRTVSCAC-PHLMKLHKDNTTCYEFKKFL---------LYARQMEIRGV 1596
Query: 2640 SVLRPVFNIKMNLIPGGID----FGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWG 2473
+ P +N ++ ID YD + ++ D+R++ I G
Sbjct: 1597 DLDAPYYNYIISFTVPDIDNVTVLDYDAREQRVYWS--------DVRTQAIKRAFINGTG 1648
Query: 2472 EEE------STAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVN 2311
E A + D++ N+++T S + N+ +Q N+ D S + +V
Sbjct: 1649 VETVVSADLPNAHGLAVDWVSRNLFWT-SYDTNK-----KQINV---ARLDGSFKNAVVQ 1699
Query: 2310 STGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEP 2131
+ L V P++ ++WT I AN+DG ++ L+ P
Sbjct: 1700 GLEQPHGLVVHPLRGKLYWTDG---DNISMANMDGS------------NRTLLFSGQKGP 1744
Query: 2130 TSMVLDFSNERLYWIDVLKRTIETVSFDG 2044
+ +DF +LYWI TI + DG
Sbjct: 1745 VGLAIDFPESKLYWISSGNHTINRCNLDG 1773
Score = 49.3 bits (116), Expect = 0.001
Identities = 56/190 (29%), Positives = 68/190 (35%), Gaps = 18/190 (9%)
Frame = -1
Query: 4134 CKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPP----FPCIAGQFVCGRT 3967
C P F C CIS WR E CP P I Q R
Sbjct: 27 CSPKQFACRDQITCISKGWRCDG--------------ERDCPDGSDEAPEICPQSKAQRC 72
Query: 3966 AQN-----ATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKC---GDKKKCIP 3811
N T C+ S+LC+GV+DC G DE P C E Q C G + C+P
Sbjct: 73 QPNEHNCLGTELCVPMSRLCNGVQDCMDGSDEGP------HCRELQGNCSRLGCQHHCVP 126
Query: 3810 LTSVCDKEKDCDDGSDELNCEITSCKPDFFAC-FNGTAISKCIPKE--FYCDGEDDCPEG 3640
D + S +L + +CK DF C GT C + F C C EG
Sbjct: 127 ---TLDGPTCYCNSSFQLQADGKTCK-DFDECSVYGTCSQLCTNTDGSFIC----GCVEG 178
Query: 3639 ---QDEPDSC 3619
Q + SC
Sbjct: 179 YLLQPDNRSC 188
Score = 41.6 bits (96), Expect = 0.26
Identities = 34/126 (26%), Positives = 48/126 (37%), Gaps = 6/126 (4%)
Frame = -1
Query: 6570 DEDTKYC---STRVCRPGYFNC-GNGLCIPEQKVCNRINDCANFADESNCTCNENEFRCQ 6403
DE + C + C+P NC G LC+P ++CN + DC + +DE C E + C
Sbjct: 58 DEAPEICPQSKAQRCQPNEHNCLGTELCVPMSRLCNGVQDCMDGSDEGP-HCRELQGNC- 115
Query: 6402 SGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMT--GLINCATTSQCIHPSWKC 6229
S+ C H C D C + L G T C+ C
Sbjct: 116 ------SRLGCQH--HCVPTLDGPTCYCNSSFQLQADGKTCKDFDECSVYGTCSQLCTNT 167
Query: 6228 DGTNDC 6211
DG+ C
Sbjct: 168 DGSFIC 173
>gi|16519539|ref|NP_443737.1| low density lipoprotein-related protein
1B; low density lipoprotein receptor related protein
LRP1B/LRP-DIT [Mus musculus]
gi|46577126|sp|Q9JI18|LR1B_MOUSE Low-density lipoprotein
receptor-related protein 1B precursor (Low-density
lipoprotein receptor-related protein-deleted in tumor)
(LRP-DIT)
gi|8926243|gb|AAF81758.1| low density lipoprotein receptor related
protein LRP1B/LRP-DIT [Mus musculus]
Length = 4599
Score = 790 bits (2039), Expect = 0.0
Identities = 604/2012 (30%), Positives = 852/2012 (42%), Gaps = 181/2012 (8%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC---TCNENEFRCQS 6400
DE YC R CR G+ C N C+P K+C+ NDC + +DE +C TC+ EFRC
Sbjct: 2541 DEKLLYCENRSCRSGFKPCYNRRCVPHGKLCDGTNDCGDSSDELDCKVSTCSTVEFRCAD 2600
Query: 6399 GACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGM--TGLINCATTSQCIHPSWKCD 6226
G CIP ARCN DC+DASDE GC +C+ + G+ TG I C +TS C+ PSW CD
Sbjct: 2601 GTCIPRSARCNQNMDCSDASDEKGCNNTDCTHFYKLGVKSTGFIRCNSTSLCVLPSWICD 2660
Query: 6225 GTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCAD 6046
G+NDC D SDE C V C+ + F C + R C+ W CDGQ DC D
Sbjct: 2661 GSNDCGDYSDELKC---------PVQNKHKCE-ENYFGCPSGR-CILNTWVCDGQKDCED 2709
Query: 6045 GSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNAT- 5869
G DE +CD+ C+ +F+C S KKCI CDG DC D DE DS G T
Sbjct: 2710 GLDELHCDSS-CSWNQFAC-SVKKCISKHWICDGEDDCGDSLDES------DSICGAVTC 2761
Query: 5868 ----FRCT-NHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVV 5704
F C +H C+P W CDG DC D + L S CA T C ++ C+
Sbjct: 2762 AADMFSCQGSHACVPQHWLCDGERDCPDGSDELSS--AGCAPNNTCDENAFMCHNKVCIP 2819
Query: 5703 ACELTAVLCDGIQDCSDGFDE-KNCASLDRQCKPNEWMCDSGQC-IDSGRLCDASVDCVD 5530
+CD DC DG DE C RQC P E+ C G+C +++ CD DC D
Sbjct: 2820 K----QFVCDHDDDCGDGSDEFLQCGY--RQCGPEEFRCADGRCLVNTLWQCDGDFDCPD 2873
Query: 5529 GSDEWVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQG 5350
SDE I C S + + NG C+ LCD R DC G DE +
Sbjct: 2874 SSDE-APINPRCRSAEHSCNSSFF-MCKNGR--CIPSDGLCDIRDDCGDGSDETNCHINE 2929
Query: 5349 NCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKA-NCSHFCIDRR 5173
S + C Q +CQ C C G+ L D KTC+ C CS CI+
Sbjct: 2930 CLSKKISGCSQ--DCQDLPVSYKCKCWPGFQLKD-DGKTCVDIDECSSGFPCSQQCINTY 2986
Query: 5172 DVGHQCFCAPGYILS-ENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLTNG 4996
++C CA GY +N CR E +++ H ++ + DG L L N
Sbjct: 2987 GT-YKCHCAEGYETQPDNPNGCRSLSDEEPFLILADQHEIRKISTDGSNYTLLKQGLNNV 3045
Query: 4995 VALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIY 4816
+ALD+D + + +YW D + N + I M + +V+++ T + +AVDW+G+N+Y
Sbjct: 3046 IALDFDYREEFIYWIDSSRP-NGSRINRMCLNGSDIKVVHN--TAVPNALAVDWIGKNLY 3102
Query: 4815 YTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMD 4636
++D I V + G + +L+ L PR + LDP ++W D HIGR+ MD
Sbjct: 3103 WSDTEKRIIEVSKLNGLYPTVLVSKR-LKFPRDLSLDPRAGNLYWIDCCEYPHIGRVGMD 3161
Query: 4635 GSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIF 4456
G+N+ V+++ + R P AL +D RLY+ D ++I N DGS R V + +
Sbjct: 3162 GTNQSVVIETKISR-PMALTIDYVNHRLYWAD--ENHIEFSNMDGSHRHKVPNQDIPGVI 3218
Query: 4455 ALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTA 4276
AL +FEDY+YW+D ++ RVHK +G +R LI + + ++ H Q +
Sbjct: 3219 ALTLFEDYIYWTDGKTKSLSRVHKTSGADRLSLI-NSWHAITDIQVYHSYRQP----DVS 3273
Query: 4275 RHPCS-QPARCDNLCI--PANTPDLTTSSDNFTCMCAQGF--RSEGRSCVSECKPNDFVC 4111
+H C+ C +LC+ P T TC C F ++ R+C+S C + F C
Sbjct: 3274 KHLCTVNNGGCSHLCLLGPGKT---------HTCACPTNFYLAADNRTCLSNCTASQFRC 3324
Query: 4110 TKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYAS 3931
KT KCI WW+ CP F C G+F CG T C +
Sbjct: 3325 -KTDKCIPFWWKCDTVDDCGDGSDE----PDDCPEFKCQPGRFQCG------TGLCALPA 3373
Query: 3930 KLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNC 3751
+CDG DC GD+ + C+ C QFKC KKCIP+ C+ + DC D DE +C
Sbjct: 3374 FICDGENDC--GDNSDELNCDTHVCLAGQFKCTKNKKCIPVNLRCNGQDDCGDEEDEKDC 3431
Query: 3750 EITSCKPDFFAC-FNGTAISK-----------------------------------CIPK 3679
SC PD+F C ISK CIP
Sbjct: 3432 PENSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEANCDKKTCGPHEFQCKNNNCIPD 3491
Query: 3678 EFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQCDGTLDCRDGSDEKGC 3499
+ CD ++DC + DE D+C CT + F C++G C+ R CDG DC DGSDEK C
Sbjct: 3492 HWRCDNQNDCSDNSDE-DNC-KPQTCTLKDFLCSNGDCVSSRFWCDGEFDCADGSDEKNC 3549
Query: 3498 KKECA---IVCDN-SCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKENRKCGG----- 3346
+ C+ C N C+ A CDG + C G DE E G
Sbjct: 3550 ETSCSKDQFQCSNGQCLSAKWKCDGHEDCKYGEDEKNCEPAFPVCSSSEYMCASGGCLSA 3609
Query: 3345 -FACDGIVDCEDGSDEKGCPDLEC----HLASNKSL------ICDGTIDCSSGKDENNCH 3199
C+G DC DGSDE C +EC NK+ +CDG DC G DE C
Sbjct: 3610 SLKCNGEPDCVDGSDEMDCV-IECKEDQFQCKNKAYCIPIRWLCDGIYDCVDGSDEETCG 3668
Query: 3198 NNG---ESNFFQCSMQTIK-EWQVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQ 3031
G + F C+ K + VCDG DC D DE+P+MC R C + +
Sbjct: 3669 RGGSICRDDEFLCNNSLCKLHFWVCDGEDDCGDNSDEAPDMCVKFLCPPTRPYRCRNDRI 3728
Query: 3030 CLDVSTALCDGIRDCFDGSDENPIHC--------KDMCKGKYRCTNGRCIDV-----SAR 2890
CL + +C+GI DC D SDE HC K K ++ C+N CI + S
Sbjct: 3729 CLQLE-KICNGINDCGDNSDEE--HCSGKLSLKSKPCKKDEFTCSNRNCIPMELQCDSLD 3785
Query: 2889 XXXXXXXXXXXXXXXXGAECHHFG-VCAQKCWM-AFNHTARCHCAPGYARTKN-----DE 2731
C + G C + + C C PG+ R D
Sbjct: 3786 DCGDGSDEQGCLKTPIEHTCENNGNPCGDDAYCNQIKTSVFCRCKPGFQRNMKGRECADL 3845
Query: 2730 NEC------------------------------EPLSKSAE---MFITNGNRLHLMSLEN 2650
NEC ++K +E ++I N +
Sbjct: 3846 NECLLFGICSHHCLNTRGSYKCVCDQNFQEKNNSCIAKGSEDQALYIANDTDILGFVYPF 3905
Query: 2649 SQVSVLRPVFNIKMNLIPGGIDFGYD---VFRTTLMYTVGIGNSRVDIRSKKWSDGLIGS 2479
+ + + +++ N G+D Y + +T GI +D R K+ ++ G
Sbjct: 3906 NYSGGHQQISHVEHNSRITGMDVHYQRNVIVWSTQFNPGGIFYKMIDAREKRQANS--GL 3963
Query: 2478 WGEEESTAGLITYDFMHNNVYFTESSEQNRGVLF-----DRQANIYVAKAKDTSTRTLIV 2314
E I D++ NVY+T+ S + + + +I V + + L+
Sbjct: 3964 ICPEFKRPRDIAVDWVAGNVYWTDHSRMHWFSYYTTHWTSLRYSINVGQLNGPNCTRLLT 4023
Query: 2313 NSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFE 2134
N G ++AV+P + +++WT I A +DG + LV++N+
Sbjct: 4024 NMAGEPYAIAVNPKRGMMYWTVIGDHSHIEEAAMDG-----------TLRRVLVQKNLQR 4072
Query: 2133 PTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDT-PVTMDVLGGYIYLIT 1957
PT + +D ER+YW D I +V +DG + G P +DV YIY
Sbjct: 4073 PTGLTVDHFGERIYWADFELSIIGSVLYDGSSPVVSVSSKQGLLHPHRIDVFEDYIYGAG 4132
Query: 1956 RQGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNT 1777
+ I R+ KF G + V + V I V+H K + NPC C
Sbjct: 4133 PKNGIFRVQKF-GHGSVEVLAL-GVDKTKSILVSHRYKQ-----LNLPNPCLDLSCDFLC 4185
Query: 1776 VCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGC----S 1609
+ P C+C G++ T C D C N C
Sbjct: 4186 LLNPSG-------ATCICPEGKYMMNGT--C----HDDSLLDDSCKLTCENGGRCILNEK 4232
Query: 1608 PQKTCVCPPGFYGRQCEINECSETCWNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVC 1429
C C P + G +CE+N CS C NG TC G T C C +T +C VC
Sbjct: 4233 GDLRCHCWPSYSGGRCEVNHCSNYCQNGGTCIPSTLGRPT---CICALGFTGPNCGKAVC 4289
Query: 1428 EGVCGPRGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHKADAKVCYGHCFSGGAC-- 1255
E C GSC V ++P +C C +TG C++ VC+ +C + +C
Sbjct: 4290 EDSCHNGGSC--VVTAGNQP------YCHCQADYTGDRCQY----YVCHHYCVNSESCTI 4337
Query: 1254 --DG----------EGPL---------------------NLRCSCGDGLTGNRCQNCVGH 1174
DG EGP ++ C+C +G + CQ C G+
Sbjct: 4338 GNDGSVECVCPTRYEGPKCEIDKCVRCHGGHCIINKDNEDIFCNCTNGKIASSCQLCDGY 4397
Query: 1173 ECLNGGFCSYANSNRSLPHCICPSGFTGDHCE 1078
C NGG C + S+P C+C + ++G CE
Sbjct: 4398 -CYNGGTCQ-LDPETSIPVCVCSTNWSGTQCE 4427
Score = 374 bits (961), Expect = e-101
Identities = 266/805 (33%), Positives = 371/805 (46%), Gaps = 35/805 (4%)
Frame = -1
Query: 6540 VCRPGYFNCGN-GLCIPEQKVCNRINDCAN--FADESNCTCNEN------------EFRC 6406
+CR CG L IP +VC CA+ DE+ TC N EFRC
Sbjct: 797 MCRINNGGCGTLCLAIPAGRVCA----CADNQLLDENGTTCTFNPEEIRFHICKPGEFRC 852
Query: 6405 QSGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCD 6226
++ CI ++ +C+ DC D SDE N S ++ C ++CI W CD
Sbjct: 853 KNKHCIQARWKCDGDDDCLDGSDEDSVTCFNHSCPDD-----QFKCQN-NRCIPKRWLCD 906
Query: 6225 GTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCAD 6046
G NDC DE + R+C A QF+C R C+P W CD + DC D
Sbjct: 907 GANDCGSNEDESN----------QTCTARTCQAD-QFSCGNGR-CIPTAWLCDREDDCGD 954
Query: 6045 GSDE-KNCDAKKCTSF-EFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNA 5872
+DE +C+ C +F C+S + CI + CD DC D DE C C
Sbjct: 955 QTDEVASCEFPTCEPLTQFICKSGR-CISNKWHCDTDDDCGDRSDEVGCVHSCLDD---- 1009
Query: 5871 TFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACEL 5692
FRC++ RCIP W CDG +DC D SDE + P+ C +
Sbjct: 1010 QFRCSSGRCIPGHWACDGDNDCGDF-----SDETHINCTKEEARSPAGCIGNEFQCRPDG 1064
Query: 5691 TAV----LCDGIQDCSDGFDEKNCASLDRQCK-PNEWMCDS-GQCIDSGRLCDASVDCVD 5530
+ CDG +DC DG DEK C R C ++ C S G+CI++ +CD VDC D
Sbjct: 1065 NCIPDLWRCDGEKDCEDGSDEKGCNGTIRLCDHKTKFSCRSTGRCINNAWVCDGDVDCED 1124
Query: 5529 GSDEWVEICS--LSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQ--CD 5362
SDE E C L PP+ C N T CLQ ++LC+GR+DC G DE CD
Sbjct: 1125 QSDE--EDCDSFLCGPPKYPC--------ANDTSVCLQPEKLCNGRKDCPDGSDEGDLCD 1174
Query: 5361 NPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPK-ANCSHFC 5185
CS C + G CSC +G+ L D +TC C CS C
Sbjct: 1175 E----CSLNNGGCSNHCSVVPGRGIV-CSCPEGHQLKK-DNRTCEIVDYCASHLRCSQVC 1228
Query: 5184 IDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNL 5005
++ + +C C G+ L + + C D+ EA I+ H ++ + + L+ L
Sbjct: 1229 EQQKHMV-KCSCYEGWALGTDGESCTSVDSFEAFIIFSIRHEIRRIDLHKGDYSLLVPGL 1287
Query: 5004 TNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGR 4825
N +ALD+ L+YWTDV D G S S + V+ +G+ VDW+
Sbjct: 1288 RNTIALDFHFNQSLLYWTDVVEDRIYRGKLSESGGVSAIEVVVEHGLATPEGLTVDWIAG 1347
Query: 4824 NIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGAS-AHIGR 4648
NIY+ D N D I V + G L+ G + PRAI LDP ++FWTDW A+ I
Sbjct: 1348 NIYWIDSNLDQIEVSKLDGSLRATLIAGA-MEHPRAIALDPRYGILFWTDWDANFPRIES 1406
Query: 4647 MNMDGSNEQVILQD-RTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGS 4471
+M G+ + I +D +T WPN L VD +R+ + DA D I S YDG+ ++RG
Sbjct: 1407 ASMSGAGRKTIYKDMKTGAWPNGLTVDHFERRIVWTDARSDAIYSAFYDGTNMIEIIRGH 1466
Query: 4470 --VRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQS 4297
+ H FA++++ VYW+DW +T+ + +K TG N V IQ +P +I HPS Q
Sbjct: 1467 EYLSHPFAVSLYGSEVYWTDWRTNTLAKANKWTGQNVSV-IQKTSAQPFDLQIYHPSRQP 1525
Query: 4296 MGSLKTARHPCSQ---PARCDNLCI 4231
A +PC+ C +LC+
Sbjct: 1526 Q-----APNPCAANEGRGPCSHLCL 1545
Score = 346 bits (887), Expect = 5e-93
Identities = 442/1835 (24%), Positives = 652/1835 (35%), Gaps = 230/1835 (12%)
Frame = -1
Query: 5214 CPKAN--CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTI 5041
C K N C C+ R + C CA GY+ + C R+ E ++Y R L +I
Sbjct: 2147 CAKENGGCQQLCLYRGNSRRTCACAHGYLAGDGVT-CLRH-----EGYLLYSGRTILKSI 2200
Query: 5040 DGHAKATLLSNLT---------NGVALDYDVK-----SDLVYWTDVAHDGNKAGITSMSN 4903
+ L S + N +AL +D ++ ++++D AH GN I N
Sbjct: 2201 HLSDETNLNSPVRPYENPNYFKNIIALAFDYNQRREGTNRIFYSD-AHFGNIQLIKD--N 2257
Query: 4902 QPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIA---VCDMR-GRFNRILLKGTP 4735
+ ++ ++ + ++G+A +Y+T + +I V R G +R +
Sbjct: 2258 WEDRQVIVENVGS--VEGLAYHRAWDTLYWTSSSTSSITRHTVDQTRPGAIDREAVITMS 2315
Query: 4734 LND-PRAIVLDPLQALVFWTDWGAS-AHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPA 4561
+D P + LD Q L+FWT+W I R + G N V++ I PN L +D A
Sbjct: 2316 EDDHPHVLALDECQNLMFWTNWNEQHPSIMRATLTGKNAHVVVST-DILTPNGLTIDHRA 2374
Query: 4560 QRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKI 4381
++LYF D I C YDGS+R ++++ +LAV++ Y++WSDW I R +K
Sbjct: 2375 EKLYFSDGSLGKIERCEYDGSQRHVIVKSGPGTFLSLAVYDSYIFWSDWGRRAILRSNKY 2434
Query: 4380 TGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQ-PARCDNLCIPANTPDLTT 4204
TG K+L D ++PMG V S PC+ C +LC+ TPD
Sbjct: 2435 TGGETKILRSDIPHQPMGIIAVANDTNSC-----ELSPCALLNGGCHDLCLL--TPD--- 2484
Query: 4203 SSDNFTCMCAQGFRSEGRSCVSECKPN---DFVCTKTYKCISSWWRXXXXXXXXXXXXXG 4033
N +C + + R N +F C C+
Sbjct: 2485 GRVNCSCRGDRVLLANNRCVTKNSSCNIYSEFECGNG-DCVDYVLTCDGIPHCKDKSDEK 2543
Query: 4032 YFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECT 3853
C C +G C +C+ KLCDG DC GD + C+ C+
Sbjct: 2544 LLY---CENRSCRSGFKPC------YNRRCVPHGKLCDGTNDC--GDSSDELDCKVSTCS 2592
Query: 3852 EAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSC--------KPDFFACFNGTAI 3697
+F+C D CIP ++ C++ DC D SDE C T C K F N T++
Sbjct: 2593 TVEFRCADGT-CIPRSARCNQNMDCSDASDEKGCNNTDCTHFYKLGVKSTGFIRCNSTSL 2651
Query: 3696 SKCIPKEFYCDGEDDCPEGQDEPDSCF-GIGECTHEQFQCTSGKCIPKRRQCDGTLDCRD 3520
C+ + CDG +DC + DE +C F C SG+CI CDG DC D
Sbjct: 2652 --CVLPSWICDGSNDCGDYSDELKCPVQNKHKCEENYFGCPSGRCILNTWVCDGQKDCED 2709
Query: 3519 GSDEKGCKKECA---IVCD-NSCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKENRKC 3352
G DE C C+ C C+ +CDG+ C D DE + C + C
Sbjct: 2710 GLDELHCDSSCSWNQFACSVKKCISKHWICDGEDDCGDSLDESDSICGAVTCAA-DMFSC 2768
Query: 3351 GG--------FACDGIVDCEDGSDE---KGCPD--------LECH--LASNKSLICDGTI 3235
G + CDG DC DGSDE GC CH + K +CD
Sbjct: 2769 QGSHACVPQHWLCDGERDCPDGSDELSSAGCAPNNTCDENAFMCHNKVCIPKQFVCDHDD 2828
Query: 3234 DCSSGKDEN---NCHNNGESNFF----QCSMQTIKEWQVCDGRWDCADGLDESP--EMCA 3082
DC G DE G F +C + T+ WQ CDG +DC D DE+P C
Sbjct: 2829 DCGDGSDEFLQCGYRQCGPEEFRCADGRCLVNTL--WQ-CDGDFDCPDSSDEAPINPRCR 2885
Query: 3081 SRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKGKYRCTNGRCID 2902
S + C + +C+ S LCD DC DGSDE H + K + C D
Sbjct: 2886 SAEHSCNSSFFMCKNGRCIP-SDGLCDIRDDCGDGSDETNCHINECLSKKISGCSQDCQD 2944
Query: 2901 V----SARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKND 2734
+ + EC C+Q+C + T +CHCA GY ++
Sbjct: 2945 LPVSYKCKCWPGFQLKDDGKTCVDIDECSSGFPCSQQCINTYG-TYKCHCAEGYETQPDN 3003
Query: 2733 ENECEPLS-KSAEMFITNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTT 2557
N C LS + + + + + + +S + S ++L+ N N+I +DF Y R
Sbjct: 3004 PNGCRSLSDEEPFLILADQHEIRKISTDGSNYTLLKQGLN---NVI--ALDFDY---REE 3055
Query: 2556 LMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGLITYDFMHNNVYFTESSEQNRGVLF 2377
+Y + ++ +G + + D++ N+Y++++ ++
Sbjct: 3056 FIYWIDSSRPNGSRINRMCLNGSDIKVVHNTAVPNALAVDWIGKNLYWSDTEKR------ 3109
Query: 2376 DRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPI 2197
I V+K L+ L++DP ++W P I +DG
Sbjct: 3110 ----IIEVSKLNGLYPTVLVSKRLKFPRDLSLDPRAGNLYWIDCCEYPHIGRVGMDG--- 3162
Query: 2196 AQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKF 2017
++E I P ++ +D+ N RLYW D + IE + DG R V
Sbjct: 3163 --------TNQSVVIETKISRPMALTIDYVNHRLYWAD--ENHIEFSNMDGSHRHKVPNQ 3212
Query: 2016 ELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKH 1840
++ + + + YIY + S+ R+HK +G + IQ+ ++
Sbjct: 3213 DIPGV-IALTLFEDYIYWTDGKTKSLSRVHKTSGADRLSLINSWHAITDIQVYHSYRQPD 3271
Query: 1839 TVSHITHQKN------------PCQSDYCPSNTVCVPDQDKNGILIPKCLCGPGRFFEVS 1696
H+ N + CP+N D N + C F
Sbjct: 3272 VSKHLCTVNNGGCSHLCLLGPGKTHTCACPTNFYLAAD---NRTCLSNCTASQ---FRCK 3325
Query: 1695 TKKCMQLREKDQEASQCGDYFCYNNAGCSPQKTC---VCPPGFYGRQCEINECS------ 1543
T KC+ K CGD G C C PG + QC C+
Sbjct: 3326 TDKCIPFWWKCDTVDDCGD-------GSDEPDDCPEFKCQPGRF--QCGTGLCALPAFIC 3376
Query: 1542 -----------ETCWNGETCAVQEFGSTTNVVC-----------HCPSNYTQSSCATNVC 1429
E + C +F T N C C + C N C
Sbjct: 3377 DGENDCGDNSDELNCDTHVCLAGQFKCTKNKKCIPVNLRCNGQDDCGDEEDEKDCPENSC 3436
Query: 1428 EG---VCGPRGSC--KTVPCPKDEPHCRSYSFCECDKGWTGPH----------------- 1315
C C K C +D + CDK GPH
Sbjct: 3437 SPDYFQCKTTKHCISKLWVCDEDPDCADASDEANCDKKTCGPHEFQCKNNNCIPDHWRCD 3496
Query: 1314 ----CRHKADAKVC-------------YGHCFSGGA-CDGEGPLNLRCSCGDGLTGNRCQ 1189
C +D C G C S CDGE C DG C+
Sbjct: 3497 NQNDCSDNSDEDNCKPQTCTLKDFLCSNGDCVSSRFWCDGE------FDCADGSDEKNCE 3550
Query: 1188 --------NCVGHECLNGGF-------CSYANSNRSLPHCICPSGFTGDHCEEYLC-KDA 1057
C +CL+ + C Y ++ C F EY+C
Sbjct: 3551 TSCSKDQFQCSNGQCLSAKWKCDGHEDCKYGEDEKN-----CEPAFPVCSSSEYMCASGG 3605
Query: 1056 CPFGS-KCT-----YDITKPMD-PITCSCEQNAAAHNTDCSPI---CQ--------KQPN 931
C S KC D + MD I C +Q + C PI C
Sbjct: 3606 CLSASLKCNGEPDCVDGSDEMDCVIECKEDQFQCKNKAYCIPIRWLCDGIYDCVDGSDEE 3665
Query: 930 WCHNGGR-CLDTPGYPGKCKCLPRF--------AGPRCD-VPVQCDDY---------CTN 808
C GG C D C F G D P C + C N
Sbjct: 3666 TCGRGGSICRDDEFLCNNSLCKLHFWVCDGEDDCGDNSDEAPDMCVKFLCPPTRPYRCRN 3725
Query: 807 NSKC----TITNGTH--------FECDCKPGFKGLRCEQETKCSECSNEAKCIKKPSGTV 664
+ C I NG + C K K C+++ CSN +
Sbjct: 3726 DRICLQLEKICNGINDCGDNSDEEHCSGKLSLKSKPCKKDE--FTCSNRNCIPMELQCDS 3783
Query: 663 ICQCPQGLGGEYCEKITATSCHQLECKNGGYCLKPDPSAN--RTSPTCLCSPGF----KG 502
+ C G + C K + C+N G D N +TS C C PGF KG
Sbjct: 3784 LDDCGDGSDEQGCLKTPI----EHTCENNGNPCGDDAYCNQIKTSVFCRCKPGFQRNMKG 3839
Query: 501 LLCSS-NACENFCLHDGNCTLDEYFEPQCECYQAF 400
C+ N C F + +C L+ +C C Q F
Sbjct: 3840 RECADLNECLLFGICSHHC-LNTRGSYKCVCDQNF 3873
Score = 337 bits (863), Expect = 3e-90
Identities = 322/1267 (25%), Positives = 518/1267 (40%), Gaps = 74/1267 (5%)
Frame = -1
Query: 5247 YDKKT--CLRSPSCP------KANCSHFCIDRRDVGHQ-CFCAPGYILSENQKDCRRNDT 5095
Y K+T +RS +C CSH C+ + C C G+ + + + C+R
Sbjct: 462 YQKRTQPTVRSHACEVDAYGMPGGCSHICLLSSSYKTRTCRCRTGFNMGSDGRSCKRPKN 521
Query: 5094 IEAEILMVYG-------HRLKLFTIDGHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHD 4936
E+ + YG + L T + NL N ALD+ +++ +Y+ D
Sbjct: 522 ---ELFLFYGKGRPGIVRGMDLNTKIADECMIPIENLVNPRALDFHAEANYIYFADTT-- 576
Query: 4935 GNKAGITSMSNQPNTYR-VINSLPTKGIDGIAVDWLGRNIYYTDRNHDA---IAVCDMRG 4768
+ + T R I ++GIAVDW+G N+Y+T+ H +A +
Sbjct: 577 ---SFLIGRQKIDGTERETILKDDLDNVEGIAVDWIGNNLYWTNDGHRKTINVARLEKAS 633
Query: 4767 RFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASA---HIGRMN---MDGSNEQVILQD 4606
+ + LL+G ++ PRAIV+DP+ ++WTDW +GR+ MDG N QV +
Sbjct: 634 QSRKTLLEGG-MSHPRAIVVDPVNGWMYWTDWKEDKIDDSVGRIEKAWMDGVNRQVFVTS 692
Query: 4605 RTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRG-SVRHIFALAVFEDYV 4429
+ + WPN L +D LY+ DA+ D+I +G+ R++V G + H F L+ +YV
Sbjct: 693 KML-WPNGLTLDFHTSTLYWCDAYYDHIEKVFLNGTHRKVVYSGKELNHPFGLSHHGNYV 751
Query: 4428 YWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPAR 4249
+W+D+ N +I ++ + TN L++ ++ G +I P Q ++ +
Sbjct: 752 FWTDYMNGSIFQLDLM--TNEVTLLRHERAPLFGLQIYDPRKQQGDNMCRINN-----GG 804
Query: 4248 CDNLCIPANTPDLTTSSDNFTCMCAQGFRSEGRSCVSE--------CKPNDFVCTKTYKC 4093
C LC+ + +DN Q G +C CKP +F C K C
Sbjct: 805 CGTLCLAIPAGRVCACADN------QLLDENGTTCTFNPEEIRFHICKPGEFRC-KNKHC 857
Query: 4092 ISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGV 3913
I + W+ C C QF C QN +C+ LCDG
Sbjct: 858 IQARWKCDGDDDCLDGSDED---SVTCFNHSCPDDQFKC----QN--NRCIPKRWLCDGA 908
Query: 3912 KDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDEL-NCEITSC 3736
DC +DE C C QF CG+ +CIP +CD+E DC D +DE+ +CE +C
Sbjct: 909 NDCGSNEDESNQTCTARTCQADQFSCGN-GRCIPTAWLCDREDDCGDQTDEVASCEFPTC 967
Query: 3735 KP-DFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIP 3559
+P F C +G +CI +++CD +DDC + DE + C +QF+C+SG+CIP
Sbjct: 968 EPLTQFICKSG----RCISNKWHCDTDDDCGDRSDEVGC---VHSCLDDQFRCSSGRCIP 1020
Query: 3558 KRRQCDGTLDCRDGSDEK--GCKKECA----------IVC--DNSCVHADDLCDGKKKCN 3421
CDG DC D SDE C KE A C D +C+ CDG+K C
Sbjct: 1021 GHWACDGDNDCGDFSDETHINCTKEEARSPAGCIGNEFQCRPDGNCIPDLWRCDGEKDCE 1080
Query: 3420 DGSDEDEEACVIKQLLEKENRKC--------GGFACDGIVDCEDGSDEKGCPDLECHLAS 3265
DGSDE I+ K C + CDG VDCED SDE+ C C
Sbjct: 1081 DGSDEKGCNGTIRLCDHKTKFSCRSTGRCINNAWVCDGDVDCEDQSDEEDCDSFLC---- 1136
Query: 3264 NKSLICDGTIDCSSGKDENNCHNNGESNFFQCSMQTIKEWQVCDGRWDCADGLDESPEMC 3085
G + C N+ + ++ ++C+GR DC DG DE ++C
Sbjct: 1137 --------------GPPKYPCAND--------TSVCLQPEKLCNGRKDCPDGSDEG-DLC 1173
Query: 3084 ASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDG----SDENPIHCKDMCKGKYRCTN 2917
G C + + +C C +G D D C RC+
Sbjct: 1174 DECS---LNNGGCSNHCSVVPGRGIVC----SCPEGHQLKKDNRTCEIVDYCASHLRCSQ 1226
Query: 2916 GRCIDVSARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKN 2737
VC Q+ H +C C G+A +
Sbjct: 1227 ---------------------------------VCEQQ-----KHMVKCSCYEGWALGTD 1248
Query: 2736 DENECEPLSKSAEMFITNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTT 2557
E+ S A + + + + + L S+L P N I +DF F +
Sbjct: 1249 GESCTSVDSFEAFIIFSIRHEIRRIDLHKGDYSLLVPGLR---NTI--ALDFH---FNQS 1300
Query: 2556 LMYTVGIGNSRVDIRSKKWSDGLIGSWGEEE---STAGLITYDFMHNNVYFTESSEQNRG 2386
L+Y + R+ S G+ E +T +T D++ N+Y+ +S+
Sbjct: 1301 LLYWTDVVEDRIYRGKLSESGGVSAIEVVVEHGLATPEGLTVDWIAGNIYWIDSNLD--- 1357
Query: 2385 VLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTT-SAPVPRILSANLD 2209
I V+K + TLI + ++A+DP ++FWT A PRI SA++
Sbjct: 1358 -------QIEVSKLDGSLRATLIAGAMEHPRAIALDPRYGILFWTDWDANFPRIESASMS 1410
Query: 2208 G---KPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRD 2038
G K I + KTG+ P+ + +D R+ W D I + +DG +
Sbjct: 1411 GAGRKTIYKDMKTGAWPN------------GLTVDHFERRIVWTDARSDAIYSAFYDGTN 1458
Query: 2037 R-RTVRKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGKTNKYVQKIREVSPRIQI 1864
+R E P + + G +Y R ++ + +K+TG+ +QK + +
Sbjct: 1459 MIEIIRGHEYLSHPFAVSLYGSEVYWTDWRTNTLAKANKWTGQNVSVIQKTS--AQPFDL 1516
Query: 1863 RVAHPAKHTVSHITHQKNPCQSD--YCPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTK 1690
++ HP++ NPC ++ P + +C+ + +++ C C K
Sbjct: 1517 QIYHPSRQ-----PQAPNPCAANEGRGPCSHLCLINHNRSA----ACACPHLMKLSSDKK 1567
Query: 1689 KCMQLRE 1669
C ++++
Sbjct: 1568 TCYEMKK 1574
Score = 221 bits (562), Expect = 2e-55
Identities = 154/513 (30%), Positives = 250/513 (48%), Gaps = 23/513 (4%)
Frame = -1
Query: 5613 CKPNEWMC-DSGQCIDSGRLCDASVDCVDGSDEWVEICSLSEPPRRGCPSGWSCLLTNGT 5437
C P E++C D C+ LCD DC D SDE ++ C E CP + +G+
Sbjct: 32 CDPGEFLCHDHVTCVSQSWLCDGDPDCPDQSDESLDTCP--EEVEIKCPLNH--IACHGS 87
Query: 5436 IGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSSTRNSCDQTWNCQRHAGF----ESCSCD 5269
C+ +LC+G DC G DE G+C SC Q NCQ C C+
Sbjct: 88 SACVHLSKLCNGVVDCPDGFDEG-----GHCQELLPSCQQL-NCQFKCAMVRNATRCYCE 141
Query: 5268 DGYHLSPYDKKTCLRSPSCPKAN-CSHFCIDRRDVGHQCFCAPGYILSENQKDCR--RND 5098
DG+ ++ D ++C C CS C + + C C GYI+ + + C+
Sbjct: 142 DGFEVAE-DGRSCKDQDECSIYGICSQTCKNTYG-SYACSCVEGYIMQSDNRSCKVKHEP 199
Query: 5097 TIEAEILMVYG-HRLKLFTIDGHAKATLLSNLTNGV-ALDYDVKSDLVYWTDVAHDGN-- 4930
T +A +L++ ++LF I+G TL S N + LD+ +++ W + N
Sbjct: 200 TDKAPMLLISSLETIELFYINGSKMTTLSSANRNEIHTLDFIYSEEMICWIESRESSNQL 259
Query: 4929 KAGITSMSNQPNTYRVINSLPT-KGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRI 4753
K G + + + R+INSL + + ++ +A DWL RNIY+ D D I VC+ G
Sbjct: 260 KCGQITKAGRLTDQRIINSLQSFQNVEQMAFDWLTRNIYFVDHVSDRIFVCNFNGSVCVT 319
Query: 4752 LLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAV 4573
L++ + L++P+AI DP+ +F+TD+G I R ++DG N I+ + P+ALA+
Sbjct: 320 LIE-SELHNPKAIAADPIAGKLFFTDYGNVPKIERCDLDGMNRTRIVYSKA-EQPSALAL 377
Query: 4572 DAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRG-SVRHIFALAVFEDYVYWSDWHNHTIE 4396
D + +Y+ D + DY+ +Y G R +++G V+H++ + VFEDY+Y + N I
Sbjct: 378 DLVNRLVYWVDLYLDYVGVVDYQGKNRHTIVQGRQVKHLYGITVFEDYLYATSSDNFNII 437
Query: 4395 RVHKITGTNRKVLIQDKQYRPMGF--KIVHPSLQSMGSLKTARHPC-----SQPARCDNL 4237
R+++ GT+ +I+ + R + K P+++S H C P C ++
Sbjct: 438 RINRFNGTDIHSIIKMESARGIRTYQKRTQPTVRS--------HACEVDAYGMPGGCSHI 489
Query: 4236 CIPANTPDLTTSSDNFTCMCAQGFR--SEGRSC 4144
C+ L++S TC C GF S+GRSC
Sbjct: 490 CL------LSSSYKTRTCRCRTGFNMGSDGRSC 516
Score = 182 bits (463), Expect = 7e-44
Identities = 120/366 (32%), Positives = 162/366 (43%), Gaps = 48/366 (13%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADE-SNC---TCNE-NEFR 6409
+DE + C+ R C+ F+CGNG CIP +C+R +DC + DE ++C TC +F
Sbjct: 915 EDESNQTCTARTCQADQFSCGNGRCIPTAWLCDREDDCGDQTDEVASCEFPTCEPLTQFI 974
Query: 6408 CQSGACIPSKARCNHMQDCNDASDEIGC-------PFR---------------------- 6316
C+SG CI +K C+ DC D SDE+GC FR
Sbjct: 975 CKSGRCISNKWHCDTDDDCGDRSDEVGCVHSCLDDQFRCSSGRCIPGHWACDGDNDCGDF 1034
Query: 6315 ------NCSALNEFGMTGLI----NCATTSQCIHPSWKCDGTNDCYDGSDEKDCFVEFDA 6166
NC+ G I C CI W+CDG DC DGSDEK C
Sbjct: 1035 SDETHINCTKEEARSPAGCIGNEFQCRPDGNCIPDLWRCDGEKDCEDGSDEKGC------ 1088
Query: 6165 TGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADGSDEKNCDAKKCTSFEFSC- 5989
G++ R CD KT+F+C +T C+ W CDG DC D SDE++CD+ C ++ C
Sbjct: 1089 -NGTI---RLCDHKTKFSCRSTGRCINNAWVCDGDVDCEDQSDEEDCDSFLCGPPKYPCA 1144
Query: 5988 ESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNATFRCTNHRCIPMAWRCDGTDD 5809
+ C+ E+ C+GR+DCPDG DE EC G C+NH C + R G
Sbjct: 1145 NDTSVCLQPEKLCNGRKDCPDGSDEGDLCDECSLNNGG----CSNH-CSVVPGR--GIVC 1197
Query: 5808 CMDNAKSLGSDEVDCAAGRTSFHVPSRCADE-TCVVACELT--AVLCDGIQDCSDGFDEK 5638
L D C + CA C CE V C + + G D +
Sbjct: 1198 SCPEGHQLKKDNRTC-------EIVDYCASHLRCSQVCEQQKHMVKCSCYEGWALGTDGE 1250
Query: 5637 NCASLD 5620
+C S+D
Sbjct: 1251 SCTSVD 1256
Score = 165 bits (418), Expect = 1e-38
Identities = 117/416 (28%), Positives = 191/416 (45%), Gaps = 25/416 (6%)
Frame = -1
Query: 5313 WNCQRHAGFESCSCDDG-------------YHLSPYDKKTCLRSPSCPKAN--CSHFCID 5179
W Q A +C+ DG H+ YDK+ S SC N CS C+
Sbjct: 1792 WADQNLAQLGTCNKRDGRNPSILRNKTSGVVHMKVYDKEAQQGSNSCQVNNGGCSQLCLP 1851
Query: 5178 RRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLTN 4999
+ C C GY L +N+ C+ IE+ ++ ++ ++ K L ++
Sbjct: 1852 TSETTRTCMCTVGYYLQKNRMSCQG---IESFLMYSVHEGIRGIPLEPRDKVDALMPISG 1908
Query: 4998 G---VALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKG---IDGIAVD 4837
V +D+ ++D +YWTD+ G+ +S + T G ++GIAVD
Sbjct: 1909 AAFAVGIDFHAENDTIYWTDM-------GLNKISRAKRDQTWKEDVVTNGLGRVEGIAVD 1961
Query: 4836 WLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAH 4657
W+ NIY+TD + I V + G F +++ L+ PR+I + P + +FWT+WG
Sbjct: 1962 WIAGNIYWTDHGFNLIEVARLNGSFRYVIIS-QGLDQPRSIAVHPEKGFLFWTEWGQVPC 2020
Query: 4656 IGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYD-GSKRRMVL 4480
IG+ +DGS E+V++ I WPN +++D +LY+ DA D I + D G+ R ++L
Sbjct: 2021 IGKARLDGS-EKVMIVSVGITWPNGISIDYEENKLYWCDARSDKIERIDLDTGANREVLL 2079
Query: 4479 RGSVRHIFALAVFEDYVYWSD--WHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPS 4306
GS +F++AVF Y+YWSD N ++ R HK T + KI +
Sbjct: 2080 SGSNVDLFSVAVFGAYIYWSDRAHANGSVRRGHKNDATETVTMRTGLGVNLKEIKIFN-R 2138
Query: 4305 LQSMGSLKTARHPCSQPARCDNLCIPANTPDLTTSSDNFTCMCAQGF-RSEGRSCV 4141
++ G+ A+ + C LC L + TC CA G+ +G +C+
Sbjct: 2139 VREKGTNVCAK----ENGGCQQLC-------LYRGNSRRTCACAHGYLAGDGVTCL 2183
Score = 124 bits (312), Expect = 2e-26
Identities = 86/273 (31%), Positives = 111/273 (40%), Gaps = 4/273 (1%)
Frame = -1
Query: 1287 CYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQ-NCVGHECLNGGFCSYANSNRSLPHCI 1111
C C +GG C +LRC C +G RC+ N + C NGG C + R P CI
Sbjct: 4217 CKLTCENGGRCILNEKGDLRCHCWPSYSGGRCEVNHCSNYCQNGGTCIPSTLGR--PTCI 4274
Query: 1110 CPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCSCEQNAAAHNTDCSPICQKQPN 931
C GFTG +C + +C+D+
Sbjct: 4275 CALGFTGPNCGKAVCEDS------------------------------------------ 4292
Query: 930 WCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSKCTITNGTHFECDCKPG 751
CHNGG C+ T G C C + G RC V C YC N+ CTI N EC C
Sbjct: 4293 -CHNGGSCVVTAGNQPYCHCQADYTGDRCQYYV-CHHYCVNSESCTIGNDGSVECVCPTR 4350
Query: 750 FKGLRCEQETKCSECSNEAKCIKKPSGTVICQCPQGLGGEYCEKITATSCHQLE--CKNG 577
++G +CE + KC C I K + + C C G KI A+SC + C NG
Sbjct: 4351 YEGPKCEID-KCVRCHGGHCIINKDNEDIFCNCTNG-------KI-ASSCQLCDGYCYNG 4401
Query: 576 GYC-LKPDPSANRTSPTCLCSPGFKGLLCSSNA 481
G C L P+ S P C+CS + G C A
Sbjct: 4402 GTCQLDPETSI----PVCVCSTNWSGTQCERPA 4430
Score = 111 bits (278), Expect = 2e-22
Identities = 83/355 (23%), Positives = 151/355 (42%), Gaps = 10/355 (2%)
Frame = -1
Query: 5199 CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTID------ 5038
CSH C+ + C C LS ++K C E + ++Y R ++ +D
Sbjct: 1540 CSHLCLINHNRSAACACPHLMKLSSDKKTC-----YEMKKFLLYARRSEIRGVDIDNPYV 1594
Query: 5037 GHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKG 4858
A + ++ + +D+D + +YWTD+ IT + S +
Sbjct: 1595 NFITAFTVPDIDDVAVIDFDASEERLYWTDI----KTQTITRAFINGTGLETVISRDIQS 1650
Query: 4857 IDGIAVDWLGRNIYYTDRNHD--AIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVF 4684
I G+AVDW+ RN+Y+ D I V + G ++ G ++ P+ + P++ ++
Sbjct: 1651 IRGLAVDWVSRNLYWISSEFDETQINVARLDGSLKTSIIHG--IDKPQCLAAHPVRGKLY 1708
Query: 4683 WTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYD 4504
WTD I NMDGSN +++ Q++ + P L++D +LY+ + I CN D
Sbjct: 1709 WTDGNT---INMANMDGSNSKILFQNQ--KEPVGLSIDYVENKLYWISSGNGTINRCNLD 1763
Query: 4503 GSKRRMV--LRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPM 4330
G ++ ++ + AL + + ++W+D + + +K G N +L R
Sbjct: 1764 GGNLEVIESMKEELTKATALTIMDKKLWWADQNLAQLGTCNKRDGRNPSIL------RNK 1817
Query: 4329 GFKIVHPSLQSMGSLKTARHPCSQPARCDNLCIPANTPDLTTSSDNFTCMCAQGF 4165
+VH + + + + C LC+P TS TCMC G+
Sbjct: 1818 TSGVVHMKVYDKEAQQGSNSCQVNNGGCSQLCLP-------TSETTRTCMCTVGY 1865
Score = 109 bits (272), Expect = 1e-21
Identities = 76/260 (29%), Positives = 104/260 (39%), Gaps = 9/260 (3%)
Frame = -1
Query: 1134 NRSLPHCICPSG---FTGDHCEEYL----CKDACPFGSKCTYDITKPMDPITCSCEQNAA 976
N S CICP G G ++ L CK C G +C I + C C + +
Sbjct: 4188 NPSGATCICPEGKYMMNGTCHDDSLLDDSCKLTCENGGRC---ILNEKGDLRCHCWPSYS 4244
Query: 975 AHNTDCSPICQKQPNWCHNGGRCL-DTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSK 799
+ + N+C NGG C+ T G P C C F GP C V C+D C N
Sbjct: 4245 GGRCEVNHCS----NYCQNGGTCIPSTLGRP-TCICALGFTGPNCGKAV-CEDSCHNGGS 4298
Query: 798 CTITNGTHFECDCKPGFKGLRCEQETKCSECSNEAKCIKKPSGTVICQCPQGLGGEYCEK 619
C +T G C C+ + G RC+ C N C G+V C CP G CE
Sbjct: 4299 CVVTAGNQPYCHCQADYTGDRCQYYVCHHYCVNSESCTIGNDGSVECVCPTRYEGPKCEI 4358
Query: 618 ITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCLHDGNCTLD 439
CH GG+C+ N+ + C+ + S C+ +C + G C LD
Sbjct: 4359 DKCVRCH------GGHCI-----INKDNEDIFCNCTNGKIASSCQLCDGYCYNGGTCQLD 4407
Query: 438 -EYFEPQCECYQAFIGDRCQ 382
E P C C + G +C+
Sbjct: 4408 PETSIPVCVCSTNWSGTQCE 4427
Score = 94.0 bits (232), Expect = 4e-17
Identities = 94/425 (22%), Positives = 172/425 (40%), Gaps = 17/425 (4%)
Frame = -1
Query: 3141 VCDGRWDCADGLDESPEMCASRKARCFRIGY--CDDKKQCLDVSTALCDGIRDCFDGSDE 2968
+CDG DC D DES + C + + C C+ +S LC+G+ DC DG DE
Sbjct: 51 LCDGDPDCPDQSDESLDTCPEEVEIKCPLNHIACHGSSACVHLSK-LCNGVVDCPDGFDE 109
Query: 2967 NPIHCKDMCKG------KYRCTNGRCIDVSARXXXXXXXXXXXXXXXXGAECHHFGVCAQ 2806
HC+++ +++C R EC +G+C+Q
Sbjct: 110 GG-HCQELLPSCQQLNCQFKCAMVRNA-TRCYCEDGFEVAEDGRSCKDQDECSIYGICSQ 167
Query: 2805 KCWMAFNHTARCHCAPGYARTKNDENEC----EPLSKSAEMFITNGNRLHLMSLENSQVS 2638
C + A C C GY ++D C EP K+ + I++ + L + S+++
Sbjct: 168 TCKNTYGSYA-CSCVEGYI-MQSDNRSCKVKHEPTDKAPMLLISSLETIELFYINGSKMT 225
Query: 2637 VLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGN----SRVDIRSKKWSDGLIGSWGE 2470
L +++ +DF Y + + N ++ + +I S
Sbjct: 226 TLSSANRNEIHT----LDFIYSEEMICWIESRESSNQLKCGQITKAGRLTDQRIINSLQS 281
Query: 2469 EESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINS 2290
++ + +D++ N+YF + + DR I+V + TLI + +
Sbjct: 282 FQNVEQM-AFDWLTRNIYFVDH-------VSDR---IFVCNFNGSVCVTLIESELHNPKA 330
Query: 2289 LAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDF 2110
+A DPI +F+T VP+I +LDG +V +P+++ LD
Sbjct: 331 IAADPIAGKLFFTDYGNVPKIERCDLDG-----------MNRTRIVYSKAEQPSALALDL 379
Query: 2109 SNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITRQG-SIHRM 1933
N +YW+D+ + V + G++R T+ + + V Y+Y + +I R+
Sbjct: 380 VNRLVYWVDLYLDYVGVVDYQGKNRHTIVQGRQVKHLYGITVFEDYLYATSSDNFNIIRI 439
Query: 1932 HKFTG 1918
++F G
Sbjct: 440 NRFNG 444
Score = 91.3 bits (225), Expect = 3e-16
Identities = 175/804 (21%), Positives = 277/804 (33%), Gaps = 78/804 (9%)
Frame = -1
Query: 2820 GVCAQKCWMAFNHTAR-CHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLE-NS 2647
G C+ C ++ ++ R C C G+ +D C+ +F G + ++ N+
Sbjct: 484 GGCSHICLLSSSYKTRTCRCRTGF-NMGSDGRSCKRPKNELFLFYGKGRPGIVRGMDLNT 542
Query: 2646 QVS--VLRPVFNIKMNLIPGGIDF----GYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLI 2485
+++ + P+ N+ + P +DF Y F T + +G R D L
Sbjct: 543 KIADECMIPIENL---VNPRALDFHAEANYIYFADTTSFLIGRQKIDGTERETILKDDLD 599
Query: 2484 GSWGEEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNST 2305
G I D++ NN+Y+T + + N+ + S +TL+
Sbjct: 600 NVEG--------IAVDWIGNNLYWTNDGHR-------KTINVARLEKASQSRKTLLEGGM 644
Query: 2304 GTINSLAVDPIKRLIFWTT------SAPVPRILSANLDGKPIAQPFKTGSQPHKALVERN 2143
++ VDP+ ++WT V RI A +DG + V
Sbjct: 645 SHPRAIVVDPVNGWMYWTDWKEDKIDDSVGRIEKAWMDGVN-----------RQVFVTSK 693
Query: 2142 IFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYL 1963
+ P + LDF LYW D IE V +G R+ V + + P + G Y++
Sbjct: 694 MLWPNGLTLDFHTSTLYWCDAYYDHIEKVFLNGTHRKVVYSGKELNHPFGLSHHGNYVFW 753
Query: 1962 IT-RQGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYC- 1789
GSI ++ TN+ E +P +++ P K ++ N C
Sbjct: 754 TDYMNGSIFQLDLM---TNEVTLLRHERAPLFGLQIYDPRKQQGDNMCRINNGGCGTLCL 810
Query: 1788 --PSNTVCVPDQ----DKNGIL-------IPKCLCGPGRFFEVSTKKCMQLREKDQEASQ 1648
P+ VC D+NG I +C PG F K C+Q R K
Sbjct: 811 AIPAGRVCACADNQLLDENGTTCTFNPEEIRFHICKPGE-FRCKNKHCIQARWKCDGDDD 869
Query: 1647 CGDYFCYNNAGCSPQKTCVCPPGFYGRQCEINECSETCW---NGETCAVQEFGSTTNVVC 1477
C D ++ C CP + +C+ N C W C E +N C
Sbjct: 870 CLDGSDEDSVTCFNHS---CPDDQF--KCQNNRCIPKRWLCDGANDCGSNE--DESNQTC 922
Query: 1476 HCPS-NYTQSSCATNVC---------EGVCGPR----GSCKTVPC-PKDEPHCRSYSFCE 1342
+ Q SC C E CG + SC+ C P + C+S C
Sbjct: 923 TARTCQADQFSCGNGRCIPTAWLCDREDDCGDQTDEVASCEFPTCEPLTQFICKS-GRCI 981
Query: 1341 CDKGW---TGPHCRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQNCVG-H 1174
+K W T C ++D C C RCS G + G+ C G +
Sbjct: 982 SNK-WHCDTDDDCGDRSDEVGCVHSCLDD---------QFRCSSGRCIPGHWA--CDGDN 1029
Query: 1173 ECLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCS 994
+C G F + N + P+G G+ E+ C+ P G+ C D+ + C
Sbjct: 1030 DC--GDFSDETHINCTKEEARSPAGCIGN---EFQCR---PDGN-CIPDLWRCDGEKDCE 1080
Query: 993 CEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDY- 817
+ N K C + GRC++ CD V C+D
Sbjct: 1081 DGSDEKGCNGTIRLCDHKTKFSCRSTGRCINNAWV--------------CDGDVDCEDQS 1126
Query: 816 ----------------CTNNSKC-----TITNGTHFECDCKPGFKGLRCEQETKCSECS- 703
C N++ + NG DC G ++ C ECS
Sbjct: 1127 DEEDCDSFLCGPPKYPCANDTSVCLQPEKLCNGRK---DCPDG-----SDEGDLCDECSL 1178
Query: 702 NEAKCIKK----PSGTVICQCPQG 643
N C P ++C CP+G
Sbjct: 1179 NNGGCSNHCSVVPGRGIVCSCPEG 1202
Score = 81.6 bits (200), Expect = 2e-13
Identities = 40/121 (33%), Positives = 56/121 (46%)
Frame = -1
Query: 708 CSNEAKCIKKPSGTVICQCPQGLGGEYCEKITATSCHQLECKNGGYCLKPDPSANRTSPT 529
C N +CI G + C C G CE C C+NGG C+ + PT
Sbjct: 4221 CENGGRCILNEKGDLRCHCWPSYSGGRCE---VNHCSNY-CQNGGTCIP----STLGRPT 4272
Query: 528 CLCSPGFKGLLCSSNACENFCLHDGNCTLDEYFEPQCECYQAFIGDRCQYRIHQHAVIFS 349
C+C+ GF G C CE+ C + G+C + +P C C + GDRCQY + H + S
Sbjct: 4273 CICALGFTGPNCGKAVCEDSCHNGGSCVVTAGNQPYCHCQADYTGDRCQYYVCHHYCVNS 4332
Query: 348 D 346
+
Sbjct: 4333 E 4333
Score = 72.4 bits (176), Expect = 1e-10
Identities = 80/307 (26%), Positives = 117/307 (38%), Gaps = 9/307 (2%)
Frame = -1
Query: 2820 GVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLE-NSQ 2644
G C+Q C T C C GY KN C+ + + G R + LE +
Sbjct: 1843 GGCSQLCLPTSETTRTCMCTVGYYLQKN-RMSCQGIESFLMYSVHEGIRG--IPLEPRDK 1899
Query: 2643 VSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEE 2464
V L P+ + GIDF + +Y +G +++ R+K+ +W E+
Sbjct: 1900 VDALMPISGAAFAV---GIDFHAE---NDTIYWTDMGLNKIS-RAKRDQ-----TWKEDV 1947
Query: 2463 STAGL-----ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGT 2299
T GL I D++ N+Y+T+ I VA+ + +I
Sbjct: 1948 VTNGLGRVEGIAVDWIAGNIYWTDHGFNL----------IEVARLNGSFRYVIISQGLDQ 1997
Query: 2298 INSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMV 2119
S+AV P K +FWT VP I A LDG +V I P +
Sbjct: 1998 PRSIAVHPEKGFLFWTEWGQVPCIGKARLDGSEKVM-----------IVSVGITWPNGIS 2046
Query: 2118 LDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITR---QG 1948
+D+ +LYW D IE + D R V ++ V G YIY R G
Sbjct: 2047 IDYEENKLYWCDARSDKIERIDLDTGANREVLLSGSNVDLFSVAVFGAYIYWSDRAHANG 2106
Query: 1947 SIHRMHK 1927
S+ R HK
Sbjct: 2107 SVRRGHK 2113
Score = 69.3 bits (168), Expect = 1e-09
Identities = 42/123 (34%), Positives = 54/123 (43%), Gaps = 7/123 (5%)
Frame = -1
Query: 6120 QFACLATRTCMPKHWQCDGQPDCADGSDEK--NCDAK---KCTSFEFSCESSKKCIPLEQ 5956
+F C TC+ + W CDG PDC D SDE C + KC +C S C+ L +
Sbjct: 36 EFLCHDHVTCVSQSWLCDGDPDCPDQSDESLDTCPEEVEIKCPLNHIACHGSSACVHLSK 95
Query: 5955 KCDGRRDCPDGEDE--HQCETECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLG 5782
C+G DCPDG DE H E + N F+C R + DG + D
Sbjct: 96 LCNGVVDCPDGFDEGGHCQELLPSCQQLNCQFKCAMVRNATRCYCEDGFEVAEDGRSCKD 155
Query: 5781 SDE 5773
DE
Sbjct: 156 QDE 158
Score = 62.0 bits (149), Expect = 2e-07
Identities = 62/251 (24%), Positives = 83/251 (32%), Gaps = 52/251 (20%)
Frame = -1
Query: 5766 CAAGRTSFHVPSR--CADETCVVACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWM 5593
C +S ++ S C + CV + CDGI C D DEK +R C+
Sbjct: 2503 CVTKNSSCNIYSEFECGNGDCVDY----VLTCDGIPHCKDKSDEKLLYCENRSCRSGFKP 2558
Query: 5592 CDSGQCIDSGRLCDASVDCVDGSDEW---VEICSLSE---------PPRRGCPSGWSC-- 5455
C + +C+ G+LCD + DC D SDE V CS E P C C
Sbjct: 2559 CYNRRCVPHGKLCDGTNDCGDSSDELDCKVSTCSTVEFRCADGTCIPRSARCNQNMDCSD 2618
Query: 5454 -------------------------LLTNGTIGCLQEQQLCDGRRDCMSGIDE------- 5371
+ N T C+ +CDG DC DE
Sbjct: 2619 ASDEKGCNNTDCTHFYKLGVKSTGFIRCNSTSLCVLPSWICDGSNDCGDYSDELKCPVQN 2678
Query: 5370 --QCDNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKANC 5197
+C+ C S R + TW C C+DG D +C C
Sbjct: 2679 KHKCEENYFGCPSGRCILN-TWVCDGQK-----DCEDGLDELHCDSSCSWNQFACSVKKC 2732
Query: 5196 --SHFCIDRRD 5170
H+ D D
Sbjct: 2733 ISKHWICDGED 2743
Score = 60.8 bits (146), Expect = 4e-07
Identities = 49/198 (24%), Positives = 75/198 (37%), Gaps = 27/198 (13%)
Frame = -1
Query: 1812 NPCQSDYCPSNTVCVPDQDKNGILIPKCLC-----GPGRFFEVSTKKCMQLR-------- 1672
N C S+YC + C+P + P C+C GP V C
Sbjct: 4251 NHC-SNYCQNGGTCIPST----LGRPTCICALGFTGPNCGKAVCEDSCHNGGSCVVTAGN 4305
Query: 1671 ------EKDQEASQCGDY----FCYNNAGCS----PQKTCVCPPGFYGRQCEINECSETC 1534
+ D +C Y +C N+ C+ CVCP + G +CEI++C
Sbjct: 4306 QPYCHCQADYTGDRCQYYVCHHYCVNSESCTIGNDGSVECVCPTRYEGPKCEIDKCVRC- 4364
Query: 1533 WNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSY 1354
+G C + + ++ C+C + SSC +C+G C G+C+ P S
Sbjct: 4365 -HGGHCIINK--DNEDIFCNCTNGKIASSC--QLCDGYCYNGGTCQLDPET-------SI 4412
Query: 1353 SFCECDKGWTGPHCRHKA 1300
C C W+G C A
Sbjct: 4413 PVCVCSTNWSGTQCERPA 4430
Score = 60.1 bits (144), Expect = 7e-07
Identities = 51/186 (27%), Positives = 76/186 (40%), Gaps = 17/186 (9%)
Frame = -1
Query: 3858 CTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDEL------NCEITSCKPDFFACFNGTAI 3697
C +F C D C+ + +CD + DC D SDE EI C + AC +A
Sbjct: 32 CDPGEFLCHDHVTCVSQSWLCDGDPDCPDQSDESLDTCPEEVEI-KCPLNHIACHGSSA- 89
Query: 3696 SKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHE---QFQCTSGKCIPKRRQCDGTLDC 3526
C+ C+G DCP+G DE C + + QF+C + +C C
Sbjct: 90 --CVHLSKLCNGVVDCPDGFDEGGHCQELLPSCQQLNCQFKCA---MVRNATRC----YC 140
Query: 3525 RDG----SDEKGCK--KECAI--VCDNSCVHADDLCDGKKKCNDGSDEDEEACVIKQLLE 3370
DG D + CK EC+I +C +C + G C +CV +++
Sbjct: 141 EDGFEVAEDGRSCKDQDECSIYGICSQTCKNT----YGSYAC---------SCVEGYIMQ 187
Query: 3369 KENRKC 3352
+NR C
Sbjct: 188 SDNRSC 193
Score = 55.1 bits (131), Expect = 2e-05
Identities = 62/276 (22%), Positives = 111/276 (39%), Gaps = 7/276 (2%)
Frame = -1
Query: 2820 GVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQV 2641
G C+ C + N +A C C P + +D+ C + K + + + + ++N V
Sbjct: 1538 GPCSHLCLINHNRSAACAC-PHLMKLSSDKKTCYEMKKF--LLYARRSEIRGVDIDNPYV 1594
Query: 2640 SVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEE-- 2467
+ + F + IDF D L +T DI+++ + I G E
Sbjct: 1595 NFIT-AFTVPDIDDVAVIDF--DASEERLYWT--------DIKTQTITRAFINGTGLETV 1643
Query: 2466 -----ESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTG 2302
+S GL D++ N+Y+ S FD + I VA+ D S +T I++
Sbjct: 1644 ISRDIQSIRGLAV-DWVSRNLYWISSE-------FD-ETQINVARL-DGSLKTSIIHGID 1693
Query: 2301 TINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSM 2122
LA P++ ++WT + AN+DG + ++ +N EP +
Sbjct: 1694 KPQCLAAHPVRGKLYWTDGNTINM---ANMDGS------------NSKILFQNQKEPVGL 1738
Query: 2121 VLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFE 2014
+D+ +LYWI TI + DG + + +
Sbjct: 1739 SIDYVENKLYWISSGNGTINRCNLDGGNLEVIESMK 1774
Score = 52.4 bits (124), Expect = 1e-04
Identities = 51/175 (29%), Positives = 65/175 (37%), Gaps = 7/175 (4%)
Frame = -1
Query: 6030 NCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDE--HQCETECDSKGGNATFRC- 5860
N D C EF C C+ CDG DCPD DE C E + K C
Sbjct: 26 NQDQHLCDPGEFLCHDHVTCVSQSWLCDGDPDCPDQSDESLDTCPEEVEIKCPLNHIACH 85
Query: 5859 TNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACEL--TA 5686
+ C+ ++ C+G DC D G DE G +PS C C C + A
Sbjct: 86 GSSACVHLSKLCNGVVDCPD-----GFDE----GGHCQELLPS-CQQLNCQFKCAMVRNA 135
Query: 5685 VLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDAS--VDCVDG 5527
C C DGF+ A R CK + G C + + S CV+G
Sbjct: 136 TRC----YCEDGFE---VAEDGRSCKDQDECSIYGICSQTCKNTYGSYACSCVEG 183
Score = 51.2 bits (121), Expect = 3e-04
Identities = 47/175 (26%), Positives = 69/175 (38%), Gaps = 14/175 (8%)
Frame = -1
Query: 6540 VCRPGYFNCGNGL-CIPEQKVCNRINDCANFADESNCTCNEN-EFRCQ--------SGAC 6391
+C PG F C + + C+ + +C+ DC + +DES TC E E +C S AC
Sbjct: 31 LCDPGEFLCHDHVTCVSQSWLCDGDPDCPDQSDESLDTCPEEVEIKCPLNHIACHGSSAC 90
Query: 6390 IPSKARCNHMQDCNDASDEIG-CP--FRNCSALNEFGMTGLINCATTSQCIHPSWKCDGT 6220
+ CN + DC D DE G C +C LN ++ AT C +
Sbjct: 91 VHLSKLCNGVVDCPDGFDEGGHCQELLPSCQQLNCQFKCAMVRNATRCYCEDGFEVAEDG 150
Query: 6219 NDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLA-TRTCMPKHWQCDGQP 6058
C D DE + T + +C + + R+C KH D P
Sbjct: 151 RSCKD-QDECSIYGICSQTCKNTYGSYACSCVEGYIMQSDNRSCKVKHEPTDKAP 204
Score = 48.5 bits (114), Expect = 0.002
Identities = 68/264 (25%), Positives = 92/264 (34%), Gaps = 39/264 (14%)
Frame = -1
Query: 1632 CYNNAGCSPQKTCVCPPGFYGRQCEINECSETCWNGET-CAVQEFGSTTNVVCHCPSNYT 1456
C N A C P + +C G Y C ETC G + C EF +C+
Sbjct: 3639 CKNKAYCIPIRW-LCD-GIY--DCVDGSDEETCGRGGSICRDDEF------LCN------ 3682
Query: 1455 QSSCATN--VCEGV--CGPRGS-----CKTVPCPKDEPH-CRSYSFC-----------EC 1339
S C + VC+G CG C CP P+ CR+ C +C
Sbjct: 3683 NSLCKLHFWVCDGEDDCGDNSDEAPDMCVKFLCPPTRPYRCRNDRICLQLEKICNGINDC 3742
Query: 1338 DKGWTGPHCRHKAD--AKVCYGHCFSGGACDGEG--PLNLRCS----CGDGLTGNRC-QN 1186
HC K +K C F+ C P+ L+C CGDG C +
Sbjct: 3743 GDNSDEEHCSGKLSLKSKPCKKDEFT---CSNRNCIPMELQCDSLDDCGDGSDEQGCLKT 3799
Query: 1185 CVGHECLNGGF-C---SYANSNRSLPHCICPSGFT----GDHCEEYLCKDACPFGSKCTY 1030
+ H C N G C +Y N ++ C C GF G C + + C C++
Sbjct: 3800 PIEHTCENNGNPCGDDAYCNQIKTSVFCRCKPGFQRNMKGRECADL---NECLLFGICSH 3856
Query: 1029 DITKPMDPITCSCEQNAAAHNTDC 958
C C+QN N C
Sbjct: 3857 HCLNTRGSYKCVCDQNFQEKNNSC 3880
Score = 47.0 bits (110), Expect = 0.006
Identities = 44/169 (26%), Positives = 60/169 (35%), Gaps = 11/169 (6%)
Frame = -1
Query: 6450 ADESNCTCNENEFRCQSGA-CIPSKARCNHMQDCNDASDE----------IGCPFRNCSA 6304
A++ C+ EF C C+ C+ DC D SDE I CP +
Sbjct: 25 ANQDQHLCDPGEFLCHDHVTCVSQSWLCDGDPDCPDQSDESLDTCPEEVEIKCPLNH--- 81
Query: 6303 LNEFGMTGLINCATTSQCIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAK 6124
I C +S C+H S C+G DC DG DE E P
Sbjct: 82 ---------IACHGSSACVHLSKLCNGVVDCPDGFDEGGHCQEL--------LPSCQQLN 124
Query: 6123 TQFACLATRTCMPKHWQCDGQPDCADGSDEKNCDAKKCTSFEFSCESSK 5977
QF C R + + DG DG K D +C+ + ++ K
Sbjct: 125 CQFKCAMVRNATRCYCE-DGFEVAEDGRSCK--DQDECSIYGICSQTCK 170
Score = 45.8 bits (107), Expect = 0.014
Identities = 36/129 (27%), Positives = 53/129 (40%), Gaps = 23/129 (17%)
Frame = -1
Query: 3468 SCVHADDLCDGKKKCNDGSDEDEEACV--IKQLLEKENRKCGGFA--------CDGIVDC 3319
+CV LCDG C D SDE + C ++ + C G + C+G+VDC
Sbjct: 44 TCVSQSWLCDGDPDCPDQSDESLDTCPEEVEIKCPLNHIACHGSSACVHLSKLCNGVVDC 103
Query: 3318 EDGSDEKG--------CPDLECHLASNKSLICDGT-IDCSSG----KDENNCHNNGESNF 3178
DG DE G C L C +++ + T C G +D +C + E +
Sbjct: 104 PDGFDEGGHCQELLPSCQQLNCQFKC--AMVRNATRCYCEDGFEVAEDGRSCKDQDECSI 161
Query: 3177 FQCSMQTIK 3151
+ QT K
Sbjct: 162 YGICSQTCK 170
Score = 42.7 bits (99), Expect = 0.12
Identities = 45/178 (25%), Positives = 62/178 (34%), Gaps = 6/178 (3%)
Frame = -1
Query: 4134 CKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPP---FPCIAGQFVCGRTA 3964
C P +F+C C+S W CP C C
Sbjct: 32 CDPGEFLCHDHVTCVSQSWLCDGDPDCPDQSDESL---DTCPEEVEIKCPLNHIAC---- 84
Query: 3963 QNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEK 3784
+ ++ C++ SKLC+GV DC G D E C+ + Q C K + + C
Sbjct: 85 -HGSSACVHLSKLCNGVVDCPDGFD-EGGHCQELLPSCQQLNCQFKCAMVRNATRC---- 138
Query: 3783 DCDDGSDELNCEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEG---QDEPDSC 3619
C+DG E+ + SCK G C K Y C EG Q + SC
Sbjct: 139 YCEDGF-EVAEDGRSCKDQDECSIYGICSQTC--KNTYGSYACSCVEGYIMQSDNRSC 193
>gi|47229537|emb|CAG06733.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 2303
Score = 785 bits (2028), Expect = 0.0
Identities = 595/1957 (30%), Positives = 848/1957 (42%), Gaps = 184/1957 (9%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCT---CNENEFRCQS 6400
DE YC+ RVC+ GY C NG C+ CN +DC + +DE C C ++F+C+
Sbjct: 325 DEKQSYCANRVCKKGYRRCVNGRCVGHGSWCNGRDDCGDNSDEIFCNTTLCTADQFQCRD 384
Query: 6399 GACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLI--NCATTSQCIHPSWKCD 6226
G+CI + ++C+ DC DA DE+ C +CS+ G+ G+ C T+ C PSW CD
Sbjct: 385 GSCISNSSKCDQKVDCEDAGDEMNCTATDCSSYFHLGVKGVTFQKCEFTTLCYAPSWLCD 444
Query: 6225 GTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCAD 6046
G NDC D SDE++C S+ C FAC + R C+PK W CD + DC +
Sbjct: 445 GANDCGDFSDERNC---------PGSSKEKCPTPF-FACPSGR-CIPKSWTCDKENDCEN 493
Query: 6045 GSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEH-QCETECDSKGGNAT 5869
G+DE +CD K C++ +F C ++ +CIP CDG DC D DE QC+T+ S
Sbjct: 494 GADEAHCD-KFCSATQFQC-ANNRCIPQRWVCDGADDCGDSSDEDSQCKTKTCSP---EA 548
Query: 5868 FRCT-NHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACEL 5692
F+C +H CIP W+CDG DC D S + C T C + C+
Sbjct: 549 FQCPGSHMCIPQRWKCDGDKDCPDGTDE--SVKAGCVFNNTCSSNEFMCQNRQCIPK--- 603
Query: 5691 TAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQC-IDSGRLCDASVDCVDGSDEW 5515
+CD DC DG DE C P E+ C +G+C I S CD DC D SDE
Sbjct: 604 -HFVCDHDNDCGDGSDESQECEYPT-CGPKEFRCANGRCLIQSSWECDGDFDCHDQSDEA 661
Query: 5514 VEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSST 5335
P + + ++C +NG C+ E LCD + DC G DE +S
Sbjct: 662 PLNPRCGGPANKCNNTAYAC--SNGN--CVNETLLCDRKDDCGDGSDELNCFINECLNSK 717
Query: 5334 RNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKAN-CSHFCIDRRDVGHQ 5158
+ C Q + GF+ C C G+ L D+KTC+ C C+ CI+ H
Sbjct: 718 LSGCSQLCEDLK-IGFK-CRCHPGFRLKD-DRKTCIDIDECTTTYPCTQRCINTHGSFH- 773
Query: 5157 CFCAPGYILS-ENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSN--------- 5008
C C GY LS EN C+ E ++ + L+ +DG + TLL
Sbjct: 774 CLCVEGYHLSPENPTICKSTSDEEPFLIFANRYYLRKLNLDG-SNYTLLKQVRLAFTLFS 832
Query: 5007 -------------------------LTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSN 4903
L N VALD+D + ++YWTDV G+ I M
Sbjct: 833 GVALKDTRRVCCGPRLTELHVLQQGLNNAVALDFDYRQQMIYWTDVTTQGSM--IRRMYI 890
Query: 4902 QPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDP 4723
+ +V++ DG+AVDW+G N+Y+ D+ D I V + G + +L+ + L +P
Sbjct: 891 NGSDVQVLHRTSLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVN-SGLREP 949
Query: 4722 RAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFG 4543
RA+ +D ++W+DWG + HIGR+ MDG+N +I++++ I WPN L +D R+Y+
Sbjct: 950 RAVAVDVRYGYLYWSDWGDNPHIGRIGMDGTNRSIIIEEK-ITWPNGLTLDFVNDRIYWA 1008
Query: 4542 DAHRDYIASCNYDGSKRRM-------------------------------VLRGSVRHIF 4456
DA DYIA + DG++R VL + HIF
Sbjct: 1009 DAREDYIAFASLDGTRRHTSKTHTHTHTFELKNDRYSNVAPDCCLWVRCTVLVKDIPHIF 1068
Query: 4455 ALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTA 4276
A+++FE+Y+YW+DW +I R HK GTN+ VLI +RPM I HP Q +
Sbjct: 1069 AMSLFEEYIYWTDWETKSINRAHKTLGTNKTVLI-STLHRPMDIHIYHPYRQP----EVE 1123
Query: 4275 RHPCS-QPARCDNLCIPANTPDLTTSSDNFTCMCAQGF--RSEGRSCVSECKPNDFVCTK 4105
HPC C NLC L + + C C F ++G+ C+S C + FVC K
Sbjct: 1124 NHPCQMNNGGCSNLC-------LISPGGGYQCACPTNFYLAADGKQCLSNCTASQFVC-K 1175
Query: 4104 TYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKL 3925
KCI WW+ CP F C GQF CG T C + +
Sbjct: 1176 NDKCIPFWWKCDTEDDCGDRSDE----PADCPEFKCRPGQFQCG------TGICTNPAYI 1225
Query: 3924 CDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEI 3745
CDG DC DE A C+ C +QFKC +CIP C+ + +C +G DE +C
Sbjct: 1226 CDGDNDCHDNSDE--ANCDIHVCLPSQFKCTSPSRCIPGIFRCNSQDNCGEGEDEKDCPE 1283
Query: 3744 TSCKPDFFACFNGTAISK-CIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQC-TSG 3571
+C P+ F C AI+K CIP+ + CD ++DC +G DEP +C + C ++F+C SG
Sbjct: 1284 VTCAPNQFQC----AITKRCIPRVWVCDRDNDCVDGSDEPANCTQM-TCGVDEFRCKDSG 1338
Query: 3570 KCIPKRRQCDGTLDCRDGSDEKGCKKEC-AIVCD--------NSCVHADDLCDGKKKCND 3418
+CIP R +CDG DC D SDE K+EC C+ N CV CD C D
Sbjct: 1339 RCIPARWKCDGEDDCGDASDEP--KEECDERTCEPYQFRCKNNRCVPGRWQCDYDNDCGD 1396
Query: 3417 GSDEDEEACVIKQLLEKE----NRKC--GGFACDGIVDCEDGSDEKGCP---DLECHLAS 3265
SDED+ CV +Q E E N +C G + CDG DC DGSDE GC D + +
Sbjct: 1397 NSDEDK--CVPRQCSESEFACTNGRCIAGRWKCDGDHDCADGSDENGCEVKCDSDQYQCK 1454
Query: 3264 NKSLI-----CDGTIDCSSGKDENNCHN----NGESNFFQCSMQTIKE--WQVCDGRWDC 3118
N I CD DC G DE C + + + FQC+ K W+ CDG DC
Sbjct: 1455 NSHCIPLRWHCDADPDCLDGSDEEKCDSGVVRHCPKDEFQCNNTLCKPQGWK-CDGEDDC 1513
Query: 3117 ADGLDESPEMC-------ASRKARCFR---------------IGYCDDKKQ--CLDVSTA 3010
D DE+PE C A R+A F I C +Q CL+
Sbjct: 1514 GDNSDENPEECGEDFYGSAFRQAVLFHRYVLIHSELLVCLSVIFQCPPTRQFRCLNDRVC 1573
Query: 3009 L-----CDGIRDCFDGSDENPIHCK-----DMC-KGKYRCTNGRCIDVSAR-------XX 2884
L CDG+ +C D SDE + C+ +C K +++C+NGRCI R
Sbjct: 1574 LPLSKRCDGVNNCGDNSDE--LDCQVPPPIPVCQKHEFQCSNGRCISSIFRCNYFNDCED 1631
Query: 2883 XXXXXXXXXXXXXXGAECH-HFGVC--AQKCWMAFNHT-ARCHCAPGYARTKNDENECEP 2716
+C + VC + N T + C C PG+ N N CE
Sbjct: 1632 YGSDEINCNKKDTALNDCRSNRTVCGDGDEAHCVVNGTDSFCSCRPGF--QTNGRNRCEG 1689
Query: 2715 LSKSAEMF-------------ITNGNRLHLMSLENSQVSVLR---PVFNIKMNLIPGGID 2584
SA ++ + + R + SLE++ P N+ P
Sbjct: 1690 AVVSALLWRRLEVKAARDPGRLISQIRTSVCSLESAPTCATTPKDPTSAAATNISPKS-- 1747
Query: 2583 FGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGLITYDFMHNNVYFTES 2404
TT +R I K G+ W + N+Y+T+S
Sbjct: 1748 -------TT--------PARPMIPDLKMPRGIAVDW--------------VAGNLYWTDS 1778
Query: 2403 SEQNRGVLFDRQANIYVAKAKDTSTR-TLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRI 2227
I VA+ T R TLI ++ VDP + ++W P+I
Sbjct: 1779 GRD----------VIEVAQISKTHHRKTLISGMIDEPYAIVVDPQRGRMYWADWGNHPKI 1828
Query: 2226 LSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFD 2047
+A +DG + LVE+NI PT + +D+ NERLYW D I +V +
Sbjct: 1829 ETAAMDG-----------TMRETLVEKNIQWPTGLAVDYFNERLYWADAKLSLICSVRLN 1877
Query: 2046 GRDRRTVRKFELGDTPVTMDVLGGYIYLITRQGSIHRMHKFTGKTNKYVQKIREVSPRIQ 1867
G D +R+ P ++DV Y+Y +T ++ + + NK+ + E +
Sbjct: 1878 GSD-AVLRQ------PFSIDVFEDYVYGVT------YINNYVFRVNKFGKGPIE---NLT 1921
Query: 1866 IRVAHPAKHTVSHITHQ---KNPCQSDYCPSNTVCVPDQDKNGILIPKCLCGPGRFFEVS 1696
+ H + H Q NPC S C + P P C C G
Sbjct: 1922 TGMNHATDIVLYHRYKQPEVNNPCDSKKCEWLCLLSPSG-------PVCTCPNGHMLNNG 1974
Query: 1695 TKKCMQ-----LREKDQEASQCGDYFCYNNAGC----SPQKTCVCPPGFYGRQCEINECS 1543
T C++ L + C C N C Q C C P + G +CEI++C
Sbjct: 1975 T--CVETPTPTLSPIGPPSGPC-LVQCLNGGSCFLNAHKQAKCRCQPNYGGDRCEIDQCR 2031
Query: 1542 ETCWNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHC 1363
+ C NG TC GS T C C + +T +C + C+ C G+C
Sbjct: 2032 DYCKNGGTCTPSPTGSPT---CRCLTGFTGRNCNLHTCKNYCKNGGNCTV--------SS 2080
Query: 1362 RSYSFCECDKGWTGPHCRHKADAKVCYGHCFSGGACD 1252
+ C+C + G C++ C ++G C+
Sbjct: 2081 GNQPTCQCSHDFLGDQCQYSE----CPFMLYTGATCE 2113
Score = 335 bits (860), Expect = 7e-90
Identities = 399/1516 (26%), Positives = 557/1516 (36%), Gaps = 155/1516 (10%)
Frame = -1
Query: 4725 PRAIVLDPLQALVFWTDWGA-SAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLY 4549
PRA VLD Q+L+FWT+W S I R + GSN VI+ IR PN LA+D A++LY
Sbjct: 78 PRAFVLDECQSLMFWTNWNEQSPSIMRATLTGSNVIVIIGS-DIRTPNGLAIDHRAEKLY 136
Query: 4548 FGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTN 4369
F DA D I C YDG++R +VL+ H F LAV+ DY++W+DW + R +K TG +
Sbjct: 137 FSDATLDKIERCEYDGTRRYVVLKNEPVHPFGLAVYGDYIFWTDWVRRAVLRANKYTGGD 196
Query: 4368 RKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDNLCIPANTPDLTTSSDNF 4189
K+L D +PMG V S R C +LC L TS
Sbjct: 197 MKLLRADIPQQPMGIVAVANDTNSC-EFSMCR---VNNGGCQDLC-------LLTSEGRV 245
Query: 4188 TCMCAQGFRSEGRSCVSECKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGV-C 4012
C C +G R F T+KC ++ V+G C
Sbjct: 246 NCSC-RGDRKLLEDSTCSGYTTSFFFLLTWKCQTA--AFLNASSCTALNTTCNVVDGFEC 302
Query: 4011 PPFPCIAGQFVCGRTA-----------------------QNATAQCLYASKLCDGVKDCS 3901
CI C A + +C+ C+G DC
Sbjct: 303 GNGDCINYTLTCDGMAHCKDKSDEKQSYCANRVCKKGYRRCVNGRCVGHGSWCNGRDDC- 361
Query: 3900 GGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCKPDFF 3721
GD+ + FC CT QF+C D CI +S CD++ DC+D DE+NC T C F
Sbjct: 362 -GDNSDEIFCNTTLCTADQFQCRD-GSCISNSSKCDQKVDCEDAGDEMNCTATDCSSYFH 419
Query: 3720 ACFNGTAISK------CIPKEFYCDGEDDCPEGQDEPDSCFGIG--ECTHEQFQCTSGKC 3565
G K C + CDG +DC + DE +C G +C F C SG+C
Sbjct: 420 LGVKGVTFQKCEFTTLCYAPSWLCDGANDCGDFSDE-RNCPGSSKEKCPTPFFACPSGRC 478
Query: 3564 IPKRRQCDGTLDCRDGSDEKGCKKECAIV----CDNSCVHADDLCDGKKKCNDGSDEDEE 3397
IPK CD DC +G+DE C K C+ +N C+ +CDG C D SDED +
Sbjct: 479 IPKSWTCDKENDCENGADEAHCDKFCSATQFQCANNRCIPQRWVCDGADDCGDSSDEDSQ 538
Query: 3396 ACVIKQLLEKENRKCGG--------FACDGIVDCEDGSDEK---GC--------PDLEC- 3277
C K E +C G + CDG DC DG+DE GC + C
Sbjct: 539 -CKTK-TCSPEAFQCPGSHMCIPQRWKCDGDKDCPDGTDESVKAGCVFNNTCSSNEFMCQ 596
Query: 3276 -HLASNKSLICDGTIDCSSGKDEN-NCH--NNGESNF----FQCSMQTIKEWQVCDGRWD 3121
K +CD DC G DE+ C G F +C +Q+ W+ CDG +D
Sbjct: 597 NRQCIPKHFVCDHDNDCGDGSDESQECEYPTCGPKEFRCANGRCLIQS--SWE-CDGDFD 653
Query: 3120 CADGLDESP--EMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDENPIHCKD 2947
C D DE+P C +C Y C++ T LCD DC DGSDE +
Sbjct: 654 CHDQSDEAPLNPRCGGPANKCNNTAYACSNGNCVN-ETLLCDRKDDCGDGSDELNCFINE 712
Query: 2946 MCKGKYRCTNGRCIDV----SARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHT 2779
K + C D+ R EC C Q+C + + +
Sbjct: 713 CLNSKLSGCSQLCEDLKIGFKCRCHPGFRLKDDRKTCIDIDECTTTYPCTQRC-INTHGS 771
Query: 2778 ARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHL--MSLENSQVSVLRPVFNIKMN 2605
C C GY + + C+ S E F+ NR +L ++L+ S ++L+ V +
Sbjct: 772 FHCLCVEGYHLSPENPTICKSTS-DEEPFLIFANRYYLRKLNLDGSNYTLLKQV-RLAFT 829
Query: 2604 LIPG-----------------------------GIDFGYDVFRTTLMYTVGIGNSRVDIR 2512
L G +DF Y R ++Y + IR
Sbjct: 830 LFSGVALKDTRRVCCGPRLTELHVLQQGLNNAVALDFDY---RQQMIYWTDVTTQGSMIR 886
Query: 2511 SK--KWSDGLIGSWGEEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKD 2338
SD + + GL D++ N+Y+ + I V+K +
Sbjct: 887 RMYINGSDVQVLHRTSLSNPDGL-AVDWVGGNLYWCDKGRD----------TIEVSKL-N 934
Query: 2337 TSTRTLIVNS-TGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHK 2161
+ RT++VNS ++AVD ++W+ P I +DG
Sbjct: 935 GAYRTVLVNSGLREPRAVAVDVRYGYLYWSDWGDNPHIGRIGMDG-----------TNRS 983
Query: 2160 ALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRT------VRKFEL---- 2011
++E I P + LDF N+R+YW D + I S DG R T FEL
Sbjct: 984 IIIEEKITWPNGLTLDFVNDRIYWADAREDYIAFASLDGTRRHTSKTHTHTHTFELKNDR 1043
Query: 2010 ------------------GDTP--VTMDVLGGYIYLIT-RQGSIHRMHKFTGKTNKYVQK 1894
D P M + YIY SI+R HK G TNK V
Sbjct: 1044 YSNVAPDCCLWVRCTVLVKDIPHIFAMSLFEEYIYWTDWETKSINRAHKTLG-TNKTV-L 1101
Query: 1893 IREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLCGPG 1714
I + + I + HP + + +PCQ + NG CL PG
Sbjct: 1102 ISTLHRPMDIHIYHPYRQP----EVENHPCQMN--------------NGGCSNLCLISPG 1143
Query: 1713 RFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCSPQKTCVCPPGFY----GRQCEINEC 1546
G Y C CP FY G+QC N
Sbjct: 1144 -----------------------GGY------------QCACPTNFYLAADGKQCLSN-- 1166
Query: 1545 SETCWNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPH 1366
C +F + C + + C T E CG R S + CP E
Sbjct: 1167 ---------CTASQFVCKND---KCIPFWWK--CDT---EDDCGDR-SDEPADCP--EFK 1206
Query: 1365 CRSYSFCECDKGWTGPHCRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQN 1186
CR F +C G +C + CDG+ C D + N
Sbjct: 1207 CRPGQF-QCGTG-------------ICTNPAY---ICDGDN------DCHD---NSDEAN 1240
Query: 1185 CVGHECLNGGFCSYANSNRSLPHCI-------CPSGFTGDHCEEYLCKDACPFGSKCTYD 1027
C H CL F + +R +P C G C E C P +C
Sbjct: 1241 CDIHVCLPSQF-KCTSPSRCIPGIFRCNSQDNCGEGEDEKDCPEVTC---APNQFQCA-- 1294
Query: 1026 ITKPMDPITCSCEQ-----NAAAHNTDCSPI-CQKQPNWCHNGGRCLDTPGYPGKCKCLP 865
ITK P C++ + + +C+ + C C + GRC+ P + KC
Sbjct: 1295 ITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDEFRCKDSGRCI-----PARWKCDG 1349
Query: 864 R-FAGPRCDVP-VQCDDYCTNNSKCTITNGTHFECDCKPGFKGLRCEQETKCSECSNEAK 691
G D P +CD+ + N C PG +C+ + C + S+E K
Sbjct: 1350 EDDCGDASDEPKEECDERTCEPYQFRCKNNR-----CVPG--RWQCDYDNDCGDNSDEDK 1402
Query: 690 CIKKPSGTVICQCPQG 643
C+ + C G
Sbjct: 1403 CVPRQCSESEFACTNG 1418
Score = 94.0 bits (232), Expect = 4e-17
Identities = 56/170 (32%), Positives = 75/170 (43%), Gaps = 2/170 (1%)
Frame = -1
Query: 882 KCK--CLPRFAGPRCDVPVQCDDYCTNNSKCTITNGTHFECDCKPGFKGLRCEQETKCSE 709
KC+ CL +GP C P + + NN C T P + +
Sbjct: 1949 KCEWLCLLSPSGPVCTCP---NGHMLNNGTCVETP--------TPTLSPIGPPSGPCLVQ 1997
Query: 708 CSNEAKCIKKPSGTVICQCPQGLGGEYCEKITATSCHQLECKNGGYCLKPDPSANRTSPT 529
C N C C+C GG+ CE C CKNGG C P P+ SPT
Sbjct: 1998 CLNGGSCFLNAHKQAKCRCQPNYGGDRCE---IDQCRDY-CKNGGTCT-PSPTG---SPT 2049
Query: 528 CLCSPGFKGLLCSSNACENFCLHDGNCTLDEYFEPQCECYQAFIGDRCQY 379
C C GF G C+ + C+N+C + GNCT+ +P C+C F+GD+CQY
Sbjct: 2050 CRCLTGFTGRNCNLHTCKNYCKNGGNCTVSSGNQPTCQCSHDFLGDQCQY 2099
Score = 82.0 bits (201), Expect = 2e-13
Identities = 58/212 (27%), Positives = 77/212 (35%), Gaps = 23/212 (10%)
Frame = -1
Query: 1083 CEEYLCKDACPFGSKCTYDITKPMDPITCSCEQNAAAHNTDC--------SPI------C 946
C+ C+ C + P P+ C+C +N C SPI C
Sbjct: 1945 CDSKKCEWLC---------LLSPSGPV-CTCPNGHMLNNGTCVETPTPTLSPIGPPSGPC 1994
Query: 945 QKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSKCTITNGTHFEC 766
Q C NGG C KC+C P + G RC++ QC DYC N CT + C
Sbjct: 1995 LVQ---CLNGGSCFLNAHKQAKCRCQPNYGGDRCEID-QCRDYCKNGGTCTPSPTGSPTC 2050
Query: 765 DCKPGFKGLRCEQETKCSECSNEAKCIKKPSGTVICQCPQGLGGEYCE-------KITAT 607
C GF G C T + C N C CQC G+ C+ T
Sbjct: 2051 RCLTGFTGRNCNLHTCKNYCKNGGNCTVSSGNQPTCQCSHDFLGDQCQYSECPFMLYTGA 2110
Query: 606 SCHQLECK--NGGYCLKPDPSANRTSPTCLCS 517
+C +C G C+ + +R TC S
Sbjct: 2111 TCEIDKCHYCRDGECIPSNSFTSRGDFTCRSS 2142
Score = 77.8 bits (190), Expect = 3e-12
Identities = 50/173 (28%), Positives = 68/173 (38%)
Frame = -1
Query: 954 PICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSKCTITNGTH 775
P+C N G C++TP P P +GP C C N C +
Sbjct: 1961 PVCTCPNGHMLNNGTCVETPT-PTLSPIGPP-SGP-------CLVQCLNGGSCFLNAHKQ 2011
Query: 774 FECDCKPGFKGLRCEQETKCSECSNEAKCIKKPSGTVICQCPQGLGGEYCEKITATSCHQ 595
+C C+P + G RCE + C N C P+G+ C+C G G C T +
Sbjct: 2012 AKCRCQPNYGGDRCEIDQCRDYCKNGGTCTPSPTGSPTCRCLTGFTGRNCNLHTCKNY-- 2069
Query: 594 LECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCLHDGNCTLDE 436
CKNGG C ++ PTC CS F G C + C C +D+
Sbjct: 2070 --CKNGGNCTV----SSGNQPTCQCSHDFLGDQCQYSECPFMLYTGATCEIDK 2116
Score = 65.1 bits (157), Expect = 2e-08
Identities = 55/214 (25%), Positives = 81/214 (37%), Gaps = 3/214 (1%)
Frame = -1
Query: 1497 STTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSYSFCECDKGWTGP 1318
S + VC CP+ + ++ G+C P P P GP
Sbjct: 1957 SPSGPVCTCPNGHMLNN-------------GTCVETPTPTLSP--------------IGP 1989
Query: 1317 HCRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQ--NCVGHECLNGGFCSY 1144
+ C C +GG+C +C C G+RC+ C + C NGG C+
Sbjct: 1990 ------PSGPCLVQCLNGGSCFLNAHKQAKCRCQPNYGGDRCEIDQCRDY-CKNGGTCT- 2041
Query: 1143 ANSNRSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCSCEQNAAAHNT 964
S P C C +GFTG +C + CK+ C G CT ++ P TC C +
Sbjct: 2042 -PSPTGSPTCRCLTGFTGRNCNLHTCKNYCKNGGNCT--VSSGNQP-TCQCSHDFLGDQC 2097
Query: 963 DCSPICQKQPNWCHNGGRC-LDTPGYPGKCKCLP 865
S + P + G C +D Y +C+P
Sbjct: 2098 QYS----ECPFMLYTGATCEIDKCHYCRDGECIP 2127
Score = 60.1 bits (144), Expect = 7e-07
Identities = 161/721 (22%), Positives = 232/721 (31%), Gaps = 90/721 (12%)
Frame = -1
Query: 2292 SLAVDPIKRLIFWTT-SAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVL 2116
+ +D + L+FWT + P I+ A L G + ++ +I P + +
Sbjct: 80 AFVLDECQSLMFWTNWNEQSPSIMRATLTGSNVI-----------VIIGSDIRTPNGLAI 128
Query: 2115 DFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT-RQGSIH 1939
D E+LY+ D IE +DG R V K E P + V G YI+ + ++
Sbjct: 129 DHRAEKLYFSDATLDKIERCEYDGTRRYVVLKNE-PVHPFGLAVYGDYIFWTDWVRRAVL 187
Query: 1938 RMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYC----PSNTVC 1771
R +K+TG K ++ P + VA+ + N D C C
Sbjct: 188 RANKYTGGDMKLLRADIPQQPMGIVAVANDTNSCEFSMCRVNNGGCQDLCLLTSEGRVNC 247
Query: 1770 VPDQDKNGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCSPQKTCV 1591
D+ + C FF + T KC + AS C + TC
Sbjct: 248 SCRGDRKLLEDSTCSGYTTSFFFLLTWKCQTAAFLN--ASSC----------TALNTTCN 295
Query: 1590 CPPGFYGRQCEINECSETCWNGETCAVQEFGSTTNVVCHC--PSNYTQSSCATNVCE--- 1426
GF C NG+ + T + + HC S+ QS CA VC+
Sbjct: 296 VVDGF------------ECGNGDCI---NYTLTCDGMAHCKDKSDEKQSYCANRVCKKGY 340
Query: 1425 -----GVCGPRGS----------------CKTVPCPKDEPHCRSYS----FCECDKGWTG 1321
G C GS C T C D+ CR S +CD+
Sbjct: 341 RRCVNGRCVGHGSWCNGRDDCGDNSDEIFCNTTLCTADQFQCRDGSCISNSSKCDQ---K 397
Query: 1320 PHCRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQ---NCVGHE--CLNGG 1156
C D C + C L ++ G+T +C+ C C
Sbjct: 398 VDCEDAGDEMNC-----TATDCSSYFHLGVK-----GVTFQKCEFTTLCYAPSWLCDGAN 447
Query: 1155 FCSYANSNRSLPHCI---CPSGFTGDHCEEYLCKD-ACPFGSKCTYDITKPMDPITCSCE 988
C + R+ P CP+ F + K C + C + CS
Sbjct: 448 DCGDFSDERNCPGSSKEKCPTPFFACPSGRCIPKSWTCDKENDCENGADEAHCDKFCSAT 507
Query: 987 QNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCK---CLPR-FAGP---------- 850
Q A+N C Q C C D+ +CK C P F P
Sbjct: 508 QFQCANNR-----CIPQRWVCDGADDCGDSSDEDSQCKTKTCSPEAFQCPGSHMCIPQRW 562
Query: 849 RCDVPVQCDDYCTNNSK--CTITN---GTHFEC---DCKPGFKGLRCEQETKCSECSNEA 694
+CD C D + K C N F C C P K C+ + C + S+E+
Sbjct: 563 KCDGDKDCPDGTDESVKAGCVFNNTCSSNEFMCQNRQCIP--KHFVCDHDNDCGDGSDES 620
Query: 693 KCIKKPS-GTVICQCPQG--LGGEYCEKITATSCHQL--ECKNGGYCLKPDPSANRTSPT 529
+ + P+ G +C G L E CH E C P N T+
Sbjct: 621 QECEYPTCGPKEFRCANGRCLIQSSWECDGDFDCHDQSDEAPLNPRCGGPANKCNNTAYA 680
Query: 528 CL----------------CSPGFKGLLCSSNACENFCLHDGNCTLDEYFEP--QCECYQA 403
C C G L C N C N L G L E + +C C+
Sbjct: 681 CSNGNCVNETLLCDRKDDCGDGSDELNCFINECLNSKL-SGCSQLCEDLKIGFKCRCHPG 739
Query: 402 F 400
F
Sbjct: 740 F 740
Score = 46.6 bits (109), Expect = 0.008
Identities = 96/428 (22%), Positives = 138/428 (31%), Gaps = 79/428 (18%)
Frame = -1
Query: 1791 CPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGC 1612
C + CV D+ + CG F + +C+ R K CGD A
Sbjct: 1306 CDRDNDCVDGSDEPANCT-QMTCGVDEFRCKDSGRCIPARWKCDGEDDCGD------ASD 1358
Query: 1611 SPQKTC---VCPPGFYGRQCEINECSETCWNGE-----------------TCAVQEFGST 1492
P++ C C P Y +C+ N C W + C+ EF +
Sbjct: 1359 EPKEECDERTCEP--YQFRCKNNRCVPGRWQCDYDNDCGDNSDEDKCVPRQCSESEF-AC 1415
Query: 1491 TNVVC-----HCPSNYTQSSCAT----NVCEGVC-GPRGSCKTVPCPKDEPHCRSYSFC- 1345
TN C C ++ CA N CE C + CK C HC + C
Sbjct: 1416 TNGRCIAGRWKCDGDH---DCADGSDENGCEVKCDSDQYQCKNSHCIPLRWHCDADPDCL 1472
Query: 1344 ------ECDKGWTGPHC---RHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLTGNRC 1192
+CD G HC + + +C G CDGE CGD N
Sbjct: 1473 DGSDEEKCDSGVVR-HCPKDEFQCNNTLCKPQ---GWKCDGED------DCGDNSDENP- 1521
Query: 1191 QNCVGHECLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDA---CP-------FGS 1042
EC G Y ++ R + + H E +C CP
Sbjct: 1522 -----EEC---GEDFYGSAFRQ---AVLFHRYVLIHSELLVCLSVIFQCPPTRQFRCLND 1570
Query: 1041 KCTYDITKPMDPITCSCEQNAAAHNTDCS-----PICQKQPNWCHNGGRCLDTPGYPGKC 877
+ ++K D + +C N+ DC P+CQK C NG RC+ +
Sbjct: 1571 RVCLPLSKRCDGVN-NCGDNS--DELDCQVPPPIPVCQKHEFQCSNG-RCISSIF----- 1621
Query: 876 KCLPRFAGPRCDVPVQCDDYCTNNSKCT------------------------ITNGTHFE 769
RC+ C+DY ++ C + NGT
Sbjct: 1622 ---------RCNYFNDCEDYGSDEINCNKKDTALNDCRSNRTVCGDGDEAHCVVNGTDSF 1672
Query: 768 CDCKPGFK 745
C C+PGF+
Sbjct: 1673 CSCRPGFQ 1680
Score = 40.4 bits (93), Expect = 0.59
Identities = 33/146 (22%), Positives = 61/146 (41%)
Frame = -1
Query: 5043 IDGHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPT 4864
+D H T+ S + A D L++WT+ +++ N +I S
Sbjct: 64 VDRHTVVTM-SGEDHPRAFVLDECQSLMFWTNWNEQSPSIMRATLTGS-NVIVIIGS-DI 120
Query: 4863 KGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVF 4684
+ +G+A+D +Y++D D I C+ G ++LK P++ V +F
Sbjct: 121 RTPNGLAIDHRAEKLYFSDATLDKIERCEYDGTRRYVVLKNEPVHPFGLAVYGD---YIF 177
Query: 4683 WTDWGASAHIGRMNMDGSNEQVILQD 4606
WTDW A + G + +++ D
Sbjct: 178 WTDWVRRAVLRANKYTGGDMKLLRAD 203
>gi|9055270|ref|NP_061027.1| low density lipoprotein-related protein
1B; low density lipoprotein receptor related
protein-deleted in tumor [Homo sapiens]
gi|46577130|sp|Q9NZR2|LR1B_HUMAN Low-density lipoprotein
receptor-related protein 1B precursor (Low-density
lipoprotein receptor-related protein-deleted in tumor)
(LRP-DIT)
gi|7861733|gb|AAF70379.1| low density lipoprotein receptor related
protein-deleted in tumor [Homo sapiens]
Length = 4599
Score = 773 bits (1996), Expect = 0.0
Identities = 587/2020 (29%), Positives = 863/2020 (42%), Gaps = 189/2020 (9%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC---TCNENEFRCQS 6400
DE YC R CR G+ C N CIP K+C+ NDC + +DE +C TC EFRC
Sbjct: 2541 DEKLLYCENRSCRRGFKPCYNRRCIPHGKLCDGENDCGDNSDELDCKVSTCATVEFRCAD 2600
Query: 6399 GACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGM--TGLINCATTSQCIHPSWKCD 6226
G CIP ARCN DC DASDE C +C+ + G+ TG I C +TS C+ P+W CD
Sbjct: 2601 GTCIPRSARCNQNIDCADASDEKNCNNTDCTHFYKLGVKTTGFIRCNSTSLCVLPTWICD 2660
Query: 6225 GTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCAD 6046
G+NDC D SDE C V C+ + F+C + R C+ W CDGQ DC D
Sbjct: 2661 GSNDCGDYSDELKC---------PVQNKHKCE-ENYFSCPSGR-CILNTWICDGQKDCED 2709
Query: 6045 GSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNAT- 5869
G DE +CD+ C+ +F+C S++KCI CDG DC DG DE DS G T
Sbjct: 2710 GRDEFHCDSS-CSWNQFAC-SAQKCISKHWICDGEDDCGDGLDES------DSICGAITC 2761
Query: 5868 ----FRCTNHR-CIPMAWRCDGTDDCMDNAKSLGSDEVD---CAAGRTSFHVPSRCADET 5713
F C R C+P W CDG DC D GSDE+ CA T C ++
Sbjct: 2762 AADMFSCQGSRACVPRHWLCDGERDCPD-----GSDELSTAGCAPNNTCDENAFMCHNKV 2816
Query: 5712 CVVACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCI-DSGRLCDASVDC 5536
C+ +CD DC DG DE RQC E+ C G+C+ ++ CD DC
Sbjct: 2817 CIPK----QFVCDHDDDCGDGSDESPQCGY-RQCGTEEFSCADGRCLLNTQWQCDGDFDC 2871
Query: 5535 VDGSDEWVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNP 5356
D SDE + + + C S + + NG C+ LCD + DC G DE+ +
Sbjct: 2872 PDHSDE-APLNPKCKSAEQSCNSSFF-MCKNGR--CIPSGGLCDNKDDCGDGSDERNCHI 2927
Query: 5355 QGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKA-NCSHFCID 5179
S + C Q +CQ C C G+ L D KTC+ C CS CI+
Sbjct: 2928 NECLSKKVSGCSQ--DCQDLPVSYKCKCWPGFQLKD-DGKTCVDIDECSSGFPCSQQCIN 2984
Query: 5178 RRDVGHQCFCAPGY-ILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLT 5002
++C C GY I +N C+ E +++ H ++ + DG L L
Sbjct: 2985 TYGT-YKCLCTDGYEIQPDNPNGCKSLSDEEPFLILADHHEIRKISTDGSNYTLLKQGLN 3043
Query: 5001 NGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRN 4822
N +A+D+D + + +YW D + N + I M + +V+++ T + +AVDW+G+N
Sbjct: 3044 NVIAIDFDYREEFIYWIDSSRP-NGSRINRMCLNGSDIKVVHN--TAVPNALAVDWIGKN 3100
Query: 4821 IYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMN 4642
+Y++D I V + G + IL+ L PR + LDP ++W D HIGR+
Sbjct: 3101 LYWSDTEKRIIEVSKLNGLYPTILVSKR-LKFPRDLSLDPQAGYLYWIDCCEYPHIGRVG 3159
Query: 4641 MDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRH 4462
MDG+N+ V+++ + R P AL +D +RLY+ D ++I N DGS R V +
Sbjct: 3160 MDGTNQSVVIETKISR-PMALTIDYVNRRLYWAD--ENHIEFSNMDGSHRHKVPNQDIPG 3216
Query: 4461 IFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLK 4282
+ AL +FEDY+YW+D ++ R HK +G +R LI + ++ H Q
Sbjct: 3217 VIALTLFEDYIYWTDGKTKSLSRAHKTSGADRLSLIYS-WHAITDIQVYHSYRQP----D 3271
Query: 4281 TARHPCS-QPARCDNLCIPANTPDLTTSSDNFTCMCAQGF--RSEGRSCVSECKPNDFVC 4111
++H C C +LC+ A TC C F ++ R+C+S C + F C
Sbjct: 3272 VSKHLCMINNGGCSHLCLLA-------PGKTHTCACPTNFYLAADNRTCLSNCTASQFRC 3324
Query: 4110 TKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYAS 3931
KT KCI WW+ CP F C G+F CG T C +
Sbjct: 3325 -KTDKCIPFWWKCDTVDDCGDGSDE----PDDCPEFRCQPGRFQCG------TGLCALPA 3373
Query: 3930 KLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNC 3751
+CDG DC GD+ + C+ C QFKC +KCIP+ C+ + DC D DE +C
Sbjct: 3374 FICDGENDC--GDNSDELNCDTHVCLSGQFKCTKNQKCIPVNLRCNGQDDCGDEEDERDC 3431
Query: 3750 EITSCKPDFFAC-FNGTAISK-----------------------------------CIPK 3679
SC PD+F C ISK CIP
Sbjct: 3432 PENSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEANCDKKTCGPHEFQCKNNNCIPD 3491
Query: 3678 EFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQCDGTLDCRDGSDEKGC 3499
+ CD ++DC + DE ++C CT + F C +G C+ R CDG DC DGSDE+ C
Sbjct: 3492 HWRCDSQNDCSDNSDE-ENC-KPQTCTLKDFLCANGDCVSSRFWCDGDFDCADGSDERNC 3549
Query: 3498 KKECA---IVCDN-SCVHADDLCDGKKKCNDGSDEDEEAC--------VIKQLLEKENRK 3355
+ C+ C N C+ A CDG + C G EDE++C + + +
Sbjct: 3550 ETSCSKDQFRCSNGQCIPAKWKCDGHEDCKYG--EDEKSCEPASPTCSSREYICASDGCI 3607
Query: 3354 CGGFACDGIVDCEDGSDEKGCPDLEC----HLASNKS------LICDGTIDCSSGKDENN 3205
C+G DC DGSDE C EC NK+ +CDG DC G DE N
Sbjct: 3608 SASLKCNGEYDCADGSDEMDCV-TECKEDQFRCKNKAHCIPIRWLCDGIHDCVDGSDEEN 3666
Query: 3204 CHNNG---ESNFFQCSMQTIK-EWQVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDK 3037
C G ++ F C+ K + VCDG DC D DE+P+MC R C +
Sbjct: 3667 CERGGNICRADEFLCNNSLCKLHFWVCDGEDDCGDNSDEAPDMCVKFLCPSTRPHRCRNN 3726
Query: 3036 KQCLDVSTALCDGIRDCFDGSDENPIHC--------KDMCKGKYRCTNGRCIDVSAR--- 2890
+ CL S +C+GI +C D SDE+ HC + K ++ C+N +CI + +
Sbjct: 3727 RICLQ-SEQMCNGIDECGDNSDED--HCGGKLTYKARPCKKDEFACSNKKCIPMDLQCDR 3783
Query: 2889 ---------XXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKN 2737
C C Q F C C PG+ R
Sbjct: 3784 LDDCGDGSDEQGCRIAPTEYTCEDNVNPCGDDAYCNQIKTSVF-----CRCKPGFQRNMK 3838
Query: 2736 DENECEPLSK-------SAEMFITNGN-----------RLHLMSLENSQVSVL------- 2632
+ +CE L++ S + G+ R + E S+ VL
Sbjct: 3839 N-RQCEDLNECLVFGTCSHQCINVEGSYKCVCDQNFQERNNTCIAEGSEDQVLYIANDTD 3897
Query: 2631 --------------RPVFNIKMNLIPGGIDFGYD---VFRTTLMYTVGIGNSRVDIRSKK 2503
+ + +I+ N G+D Y + +T GI R+ R K+
Sbjct: 3898 ILGFIYPFNYSGDHQQISHIEHNSRITGMDVYYQRDMIIWSTQFNPGGIFYKRIHGREKR 3957
Query: 2502 WSDGLIGSWGEEESTAGLITYDFMHNNVYFTESSEQNRGVLF-----DRQANIYVAKAKD 2338
++ G E I D++ N+Y+T+ S + + + +I V +
Sbjct: 3958 QANS--GLICPEFKRPRDIAVDWVAGNIYWTDHSRMHWFSYYTTHWTSLRYSINVGQLNG 4015
Query: 2337 TSTRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKA 2158
+ L+ N G ++AV+P + +++WT I A +DG +
Sbjct: 4016 PNCTRLLTNMAGEPYAIAVNPKRGMMYWTVVGDHSHIEEAAMDG-----------TLRRI 4064
Query: 2157 LVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDT-PVTMDVL 1981
LV++N+ PT + +D+ +ER+YW D I +V +DG + + G P +D+
Sbjct: 4065 LVQKNLQRPTGLAVDYFSERIYWADFELSIIGSVLYDGSNSVVSVSSKQGLLHPHRIDIF 4124
Query: 1980 GGYIYLITRQGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQ 1801
YIY + + R+ KF + +Y+ + + ++H K NPC
Sbjct: 4125 EDYIYGAGPKNGVFRVQKFGHGSVEYL--ALNIDKTKGVLISHRYKQ-----LDLPNPCL 4177
Query: 1800 SDYCPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCGDYFCYNN 1621
C + P C+C G++ T L + + + C N
Sbjct: 4178 DLACEFLCLLNPSG-------ATCVCPEGKYLINGTCNDDSLLDDSCKLT------CENG 4224
Query: 1620 AGC----SPQKTCVCPPGFYGRQCEINECSETCWNGETCAVQEFGSTTNVVCHCPSNYTQ 1453
C C C P + G +CE+N CS C NG TC G T C C +T
Sbjct: 4225 GRCILNEKGDLRCHCWPSYSGERCEVNHCSNYCQNGGTCVPSVLGRPT---CSCALGFTG 4281
Query: 1452 SSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHKADAKVCYGHC 1273
+C VCE C G+C + ++P +C C +TG C++ VC+ +C
Sbjct: 4282 PNCGKTVCEDFCQNGGTC--IVTAGNQP------YCHCQPEYTGDRCQY----YVCHHYC 4329
Query: 1272 FSGGAC----DG----------EGPL---------------------NLRCSCGDGLTGN 1198
+ +C DG EGP ++ C+C +G +
Sbjct: 4330 VNSESCTIGDDGSXECVCPTRYEGPKCEVDKCVRCHGGHCIINKDSEDIFCNCTNGKIAS 4389
Query: 1197 RCQNCVGHECLNGGFCSYANSNRSLPHCICPSGFTGDHCE 1078
CQ C G+ C NGG C + ++P C+C + ++G CE
Sbjct: 4390 SCQLCDGY-CYNGGTCQ-LDPETNVPVCLCSTNWSGTQCE 4427
Score = 378 bits (971), Expect = e-103
Identities = 266/811 (32%), Positives = 369/811 (44%), Gaps = 41/811 (5%)
Frame = -1
Query: 6540 VCRPGYFNCGN-GLCIPEQKVCNRINDCAN--FADESNCTCNEN------------EFRC 6406
+CR C L IP +VC CA+ DE+ TC N EFRC
Sbjct: 797 MCRVNNGGCSTLCLAIPGGRVCA----CADNQLLDENGTTCTFNPGEALPHICKAGEFRC 852
Query: 6405 QSGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCD 6226
++ CI ++ +C+ DC D SDE NC N C ++CI W CD
Sbjct: 853 KNRHCIQARWKCDGDDDCLDGSDEDSV---NC--FNHSCPDDQFKCQN-NRCIPKRWLCD 906
Query: 6225 GTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKT----QFACLATRTCMPKHWQCDGQP 6058
G NDC DE + ++C A+T QF+C R C+P+ W CD +
Sbjct: 907 GANDCGSNEDESN---------------QTCTARTCQVDQFSCGNGR-CIPRAWLCDRED 950
Query: 6057 DCADGSDEK-NCDAKKCTSF-EFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSK 5884
DC D +DE +C+ C +F C+S + CI + CD DC DG DE C C
Sbjct: 951 DCGDQTDEMASCEFPTCEPLTQFVCKSGR-CISSKWHCDSDDDCGDGSDEVGCVHSCFDN 1009
Query: 5883 GGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRC------- 5725
FRC++ RCIP W CDG +DC D SDE + H P+ C
Sbjct: 1010 ----QFRCSSGRCIPGHWACDGDNDCGDF-----SDEAQINCTKEEIHSPAGCNGNEFQC 1060
Query: 5724 -ADETCVVACELTAVLCDGIQDCSDGFDEKNCASLDRQCK-PNEWMC-DSGQCIDSGRLC 5554
D CV CDG +DC DG DEK C R C ++ C +G+CI+ +C
Sbjct: 1061 HPDGNCVP----DLWRCDGEKDCEDGSDEKGCNGTIRLCDHKTKFSCWSTGRCINKAWVC 1116
Query: 5553 DASVDCVDGSDEWVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGID 5374
D +DC D SDE L PP+ C N T CLQ ++LC+G++DC G D
Sbjct: 1117 DGDIDCEDQSDEDDCDSFLCGPPKHPC--------ANDTSVCLQPEKLCNGKKDCPDGSD 1168
Query: 5373 EQ--CDNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPK-A 5203
E CD CS C + G CSC +G L+ D KTC C
Sbjct: 1169 EGYLCDE----CSLNNGGCSNHCSVVPGRGIV-CSCPEGLQLNK-DNKTCEIVDYCSNHL 1222
Query: 5202 NCSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKA 5023
CS C + +C C G+ L + + C D EA I+ H ++ + +
Sbjct: 1223 KCSQVCEQHKHTV-KCSCYEGWKLDVDGESCTSVDPFEAFIIFSIRHEIRRIDLHKRDYS 1281
Query: 5022 TLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIA 4843
L+ L N +ALD+ L+YWTDV D G S S + V+ +G+
Sbjct: 1282 LLVPGLRNTIALDFHFNQSLLYWTDVVEDRIYRGKLSESGGVSAIEVVVEHGLATPEGLT 1341
Query: 4842 VDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGAS 4663
VDW+ NIY+ D N D I V + G L+ G + PRAI LDP ++FWTDW A+
Sbjct: 1342 VDWIAGNIYWIDSNLDQIEVAKLDGSLRTTLIAGA-MEHPRAIALDPRYGILFWTDWDAN 1400
Query: 4662 -AHIGRMNMDGSNEQVILQD-RTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRR 4489
I +M G+ + I +D +T WPN L VD +R+ + DA D I S YDG+
Sbjct: 1401 FPRIESASMSGAGRKTIYKDMKTGAWPNGLTVDHFEKRIVWTDARSDAIYSALYDGTNMI 1460
Query: 4488 MVLRGS--VRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIV 4315
++RG + H FA++++ VYW+DW +T+ + +K TG N V IQ +P +I
Sbjct: 1461 EIIRGHEYLSHPFAVSLYGSEVYWTDWRTNTLSKANKWTGQNVSV-IQKTSAQPFDLQIY 1519
Query: 4314 HPSLQSMGSLKTARHPCSQ---PARCDNLCI 4231
HPS Q A +PC+ C ++C+
Sbjct: 1520 HPSRQPQ-----APNPCAANDGKGPCSHMCL 1545
Score = 357 bits (917), Expect = 2e-96
Identities = 332/1268 (26%), Positives = 519/1268 (40%), Gaps = 67/1268 (5%)
Frame = -1
Query: 5271 DDGYHLSPYDKKT--CLRSPSCP------KANCSHFCIDRRDVGHQ-CFCAPGYILSENQ 5119
++ + + Y K+T +RS +C CSH C+ + C C G+ L +
Sbjct: 454 ENAWGIRIYQKRTQPTVRSHACEVDPYGMPGGCSHICLLSSSYKTRTCRCRTGFNLGSDG 513
Query: 5118 KDCRRNDTIEAEILMVYG-------HRLKLFTIDGHAKATLLSNLTNGVALDYDVKSDLV 4960
+ C+R E+ + YG + L T + NL N ALD+ +++ +
Sbjct: 514 RSCKRPKN---ELFLFYGKGRPGIVRGMDLNTKIADEYMIPIENLVNPRALDFHAETNYI 570
Query: 4959 YWTDVAHDGNKAGITSMSNQPNTYR-VINSLPTKGIDGIAVDWLGRNIYYTDRNHDA--- 4792
Y+ D + + T R I ++GIAVDW+G N+Y+T+ H
Sbjct: 571 YFADTT-----SFLIGRQKIDGTERETILKDDLDNVEGIAVDWIGNNLYWTNDGHRKTIN 625
Query: 4791 IAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASA---HIGRMN---MDGS 4630
+A + + + LL+G ++ PR IV+DP+ ++WTDW +GR+ MDG
Sbjct: 626 VARLEKASQSRKTLLEGE-MSHPRGIVVDPVNGWMYWTDWEEDEIDDSVGRIEKAWMDGF 684
Query: 4629 NEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRG-SVRHIFA 4453
N Q+ + + + WPN L +D LY+ DA+ D+I +G+ R++V G + H F
Sbjct: 685 NRQIFVTSKML-WPNGLTLDFHTNTLYWCDAYYDHIEKVFLNGTHRKIVYSGRELNHPFG 743
Query: 4452 LAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTAR 4273
L+ +YV+W+D+ N +I ++ I T+ L++ ++ G +I P Q
Sbjct: 744 LSHHGNYVFWTDYMNGSIFQLDLI--TSEVTLLRHERPPLFGLQIYDPRKQ--------- 792
Query: 4272 HPCSQPARCDNLCIPANTPDLTTSSDNFTCMCAQGFRSEGRSCVSECKPNDFVCTKTYKC 4093
+ DN+C + + C+ G GR C C N + C
Sbjct: 793 -------QGDNMC------RVNNGGCSTLCLAIPG----GRVCA--CADNQLLDENGTTC 833
Query: 4092 ISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGV 3913
F G P C AG+F C C+ A CDG
Sbjct: 834 T--------------------FNPGEALPHICKAGEFRC------KNRHCIQARWKCDGD 867
Query: 3912 KDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELN--CEITS 3739
DC G DE+ C N C + QFKC +CIP +CD DC DE N C +
Sbjct: 868 DDCLDGSDEDSVNCFNHSCPDDQFKC-QNNRCIPKRWLCDGANDCGSNEDESNQTCTART 926
Query: 3738 CKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIP 3559
C+ D F+C NG +CIP+ + CD EDDC + DE SC QF C SG+CI
Sbjct: 927 CQVDQFSCGNG----RCIPRAWLCDREDDCGDQTDEMASCEFPTCEPLTQFVCKSGRCIS 982
Query: 3558 KRRQCDGTLDCRDGSDEKGCKKEC---AIVCDNS-CVHADDLCDGKKKCNDGSDEDEEAC 3391
+ CD DC DGSDE GC C C + C+ CDG C D SDE + C
Sbjct: 983 SKWHCDSDDDCGDGSDEVGCVHSCFDNQFRCSSGRCIPGHWACDGDNDCGDFSDEAQINC 1042
Query: 3390 VIKQLLEKENRKCGG---------------FACDGIVDCEDGSDEKGCPDLECHLASNKS 3256
+++ C G + CDG DCEDGSDEKG
Sbjct: 1043 TKEEIHSPAG--CNGNEFQCHPDGNCVPDLWRCDGEKDCEDGSDEKG------------- 1087
Query: 3255 LICDGTIDCSSGKDENNCHNNGESNFFQCSMQTIKEWQVCDGRWDCADGLDE---SPEMC 3085
C+GTI K + +C + G + I + VCDG DC D DE +C
Sbjct: 1088 --CNGTIRLCDHKTKFSCWSTG---------RCINKAWVCDGDIDCEDQSDEDDCDSFLC 1136
Query: 3084 ASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKGKYRCTNGRCI 2905
K C +D CL LC+G +DC DGSDE + C + C+N C
Sbjct: 1137 GPPKHPC-----ANDTSVCLQ-PEKLCNGKKDCPDGSDEGYL-CDECSLNNGGCSN-HCS 1188
Query: 2904 DVSARXX-----XXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTK 2740
V R C + C+Q C HT +C C G+
Sbjct: 1189 VVPGRGIVCSCPEGLQLNKDNKTCEIVDYCSNHLKCSQVC-EQHKHTVKCSCYEGWKLDV 1247
Query: 2739 NDENECEPLSKSAEMFITNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRT 2560
+ E+ A + + + + + L S+L P N I +DF F
Sbjct: 1248 DGESCTSVDPFEAFIIFSIRHEIRRIDLHKRDYSLLVPGLR---NTI--ALDFH---FNQ 1299
Query: 2559 TLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEE---STAGLITYDFMHNNVYFTESSEQNR 2389
+L+Y + R+ S G+ E +T +T D++ N+Y+ +S+
Sbjct: 1300 SLLYWTDVVEDRIYRGKLSESGGVSAIEVVVEHGLATPEGLTVDWIAGNIYWIDSNLD-- 1357
Query: 2388 GVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTT-SAPVPRILSANL 2212
I VAK + TLI + ++A+DP ++FWT A PRI SA++
Sbjct: 1358 --------QIEVAKLDGSLRTTLIAGAMEHPRAIALDPRYGILFWTDWDANFPRIESASM 1409
Query: 2211 DG---KPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGR 2041
G K I + KTG+ P+ + +D +R+ W D I + +DG
Sbjct: 1410 SGAGRKTIYKDMKTGAWPN------------GLTVDHFEKRIVWTDARSDAIYSALYDGT 1457
Query: 2040 DR-RTVRKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGKTNKYVQKIREVSPRIQ 1867
+ +R E P + + G +Y R ++ + +K+TG+ +QK +
Sbjct: 1458 NMIEIIRGHEYLSHPFAVSLYGSEVYWTDWRTNTLSKANKWTGQNVSVIQKTS--AQPFD 1515
Query: 1866 IRVAHPAKHTVSHITHQKNPCQSD--YCPSNTVCVPDQDKNGILIPKCLCGPGRFFEVST 1693
+++ HP++ NPC ++ P + +C+ + +++ C C
Sbjct: 1516 LQIYHPSRQ-----PQAPNPCAANDGKGPCSHMCLINHNRSA----ACACPHLMKLSSDK 1566
Query: 1692 KKCMQLRE 1669
K C ++++
Sbjct: 1567 KTCYEMKK 1574
Score = 357 bits (916), Expect = 2e-96
Identities = 452/1840 (24%), Positives = 664/1840 (35%), Gaps = 235/1840 (12%)
Frame = -1
Query: 5214 CPKAN--CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTI 5041
C + N C C+ R + C CA GY L+E+ C R+ E ++Y R L +I
Sbjct: 2147 CARDNGGCKQLCLYRGNSRRTCACAHGY-LAEDGVTCLRH-----EGYLLYSGRTILKSI 2200
Query: 5040 DGHAKATLLSNLT---------NGVALDYDVK-----SDLVYWTDVAHDGNKAGITSMSN 4903
+ L S + N +AL +D ++ ++++D AH GN I N
Sbjct: 2201 HLSDETNLNSPIRPYENPRYFKNVIALAFDYNQRRKGTNRIFYSD-AHFGNIQLIKD--N 2257
Query: 4902 QPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIA---VCDMR-GRFNRILLKGTP 4735
+ ++ ++ + ++G+A +Y+T +I V R G F+R +
Sbjct: 2258 WEDRQVIVENVGS--VEGLAYHRAWDTLYWTSSTTSSITRHTVDQTRPGAFDREAVITMS 2315
Query: 4734 LND-PRAIVLDPLQALVFWTDWGAS-AHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPA 4561
+D P + LD Q L+FWT+W I R + G N QV++ I PN L +D A
Sbjct: 2316 EDDHPHVLALDECQNLMFWTNWNEQHPSIMRSTLTGKNAQVVVST-DILTPNGLTIDYRA 2374
Query: 4560 QRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKI 4381
++LYF D I C YDGS+R ++++ +LAV+++Y++WSDW I R +K
Sbjct: 2375 EKLYFSDGSLGKIERCEYDGSQRHVIVKSGPGTFLSLAVYDNYIFWSDWGRRAILRSNKY 2434
Query: 4380 TGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQ-PARCDNLCIPANTPDLTT 4204
TG + K+L D ++PMG V S PC+ C +LC L T
Sbjct: 2435 TGGDTKILRSDIPHQPMGIIAVANDTNSC-----ELSPCALLNGGCHDLC-------LLT 2482
Query: 4203 SSDNFTCMCAQGFRS--EGRSCV---SECKP-NDFVCTKTYKCISSWWRXXXXXXXXXXX 4042
+ C C +G R E CV S C ++F C +CI
Sbjct: 2483 PNGRVNCSC-RGDRILLEDNRCVTKNSSCNAYSEFECGNG-ECIDYQLTCDGIPHCKDKS 2540
Query: 4041 XXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENF 3862
C C G C +C+ KLCDG DC GD+ + C+
Sbjct: 2541 DEKLLY---CENRSCRRGFKPC------YNRRCIPHGKLCDGENDC--GDNSDELDCKVS 2589
Query: 3861 ECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSC--------KPDFFACFNG 3706
C +F+C D CIP ++ C++ DC D SDE NC T C K F N
Sbjct: 2590 TCATVEFRCADGT-CIPRSARCNQNIDCADASDEKNCNNTDCTHFYKLGVKTTGFIRCNS 2648
Query: 3705 TAISKCIPKEFYCDGEDDCPEGQDEPDSCF-GIGECTHEQFQCTSGKCIPKRRQCDGTLD 3529
T++ C+ + CDG +DC + DE +C F C SG+CI CDG D
Sbjct: 2649 TSL--CVLPTWICDGSNDCGDYSDELKCPVQNKHKCEENYFSCPSGRCILNTWICDGQKD 2706
Query: 3528 CRDGSDEKGCKKECA---IVCD-NSCVHADDLCDGKKKCNDGSDEDEE-----ACVIKQL 3376
C DG DE C C+ C C+ +CDG+ C DG DE + C
Sbjct: 2707 CEDGRDEFHCDSSCSWNQFACSAQKCISKHWICDGEDDCGDGLDESDSICGAITCAADMF 2766
Query: 3375 LEKENRKC--GGFACDGIVDCEDGSDE---KGCPD--------LECH--LASNKSLICDG 3241
+ +R C + CDG DC DGSDE GC CH + K +CD
Sbjct: 2767 SCQGSRACVPRHWLCDGERDCPDGSDELSTAGCAPNNTCDENAFMCHNKVCIPKQFVCDH 2826
Query: 3240 TIDCSSGKDEN---NCHNNGESNFF----QCSMQTIKEWQVCDGRWDCADGLDESP--EM 3088
DC G DE+ G F +C + T +WQ CDG +DC D DE+P
Sbjct: 2827 DDDCGDGSDESPQCGYRQCGTEEFSCADGRCLLNT--QWQ-CDGDFDCPDHSDEAPLNPK 2883
Query: 3087 CASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKGKYRCTNGRC 2908
C S + C + +C+ S LCD DC DGSDE H + K + C
Sbjct: 2884 CKSAEQSCNSSFFMCKNGRCIP-SGGLCDNKDDCGDGSDERNCHINECLSKKVSGCSQDC 2942
Query: 2907 IDV----SARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTK 2740
D+ + EC C+Q+C + T +C C GY
Sbjct: 2943 QDLPVSYKCKCWPGFQLKDDGKTCVDIDECSSGFPCSQQCINTYG-TYKCLCTDGYEIQP 3001
Query: 2739 NDENECEPLSKSAEMFI-TNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFR 2563
++ N C+ LS I + + + +S + S ++L+ N N+I IDF Y R
Sbjct: 3002 DNPNGCKSLSDEEPFLILADHHEIRKISTDGSNYTLLKQGLN---NVI--AIDFDY---R 3053
Query: 2562 TTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGLITYDFMHNNVYFTESSEQNRGV 2383
+Y + ++ +G + + D++ N+Y++++ ++
Sbjct: 3054 EEFIYWIDSSRPNGSRINRMCLNGSDIKVVHNTAVPNALAVDWIGKNLYWSDTEKRI--- 3110
Query: 2382 LFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGK 2203
I V+K L+ L++DP ++W P I +DG
Sbjct: 3111 -------IEVSKLNGLYPTILVSKRLKFPRDLSLDPQAGYLYWIDCCEYPHIGRVGMDGT 3163
Query: 2202 PIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVR 2023
++E I P ++ +D+ N RLYW D + IE + DG R V
Sbjct: 3164 N-----------QSVVIETKISRPMALTIDYVNRRLYWAD--ENHIEFSNMDGSHRHKVP 3210
Query: 2022 KFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPA 1846
++ + + + YIY + S+ R HK +G + IQ+ ++
Sbjct: 3211 NQDIPGV-IALTLFEDYIYWTDGKTKSLSRAHKTSGADRLSLIYSWHAITDIQVYHSYRQ 3269
Query: 1845 KHTVSHITHQKN------------PCQSDYCPSNTVCVPDQDKNGILIPKCLCGPGRFFE 1702
H+ N + CP+N D N + C F
Sbjct: 3270 PDVSKHLCMINNGGCSHLCLLAPGKTHTCACPTNFYLAAD---NRTCLSNCTASQ---FR 3323
Query: 1701 VSTKKCMQLREKDQEASQCGDYFCYNNAGCSPQKTCV---CPPGFYGRQCEINECS---- 1543
T KC+ K CGD G C C PG + QC C+
Sbjct: 3324 CKTDKCIPFWWKCDTVDDCGD-------GSDEPDDCPEFRCQPGRF--QCGTGLCALPAF 3374
Query: 1542 -------------ETCWNGETCAVQEFGSTTNVVC-----------HCPSNYTQSSCATN 1435
E + C +F T N C C + C N
Sbjct: 3375 ICDGENDCGDNSDELNCDTHVCLSGQFKCTKNQKCIPVNLRCNGQDDCGDEEDERDCPEN 3434
Query: 1434 VCEG---VCGPRGSC--KTVPCPKDEPHCRSYSFCECDKGWTGPH--------------- 1315
C C C K C +D + CDK GPH
Sbjct: 3435 SCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEANCDKKTCGPHEFQCKNNNCIPDHWR 3494
Query: 1314 ------CRHKADAKVC-------------YGHCFSGGA-CDG-----EGPLNLRCSCGDG 1210
C +D + C G C S CDG +G C
Sbjct: 3495 CDSQNDCSDNSDEENCKPQTCTLKDFLCANGDCVSSRFWCDGDFDCADGSDERNCETSCS 3554
Query: 1209 LTGNRCQN---------CVGHECLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLC-KD 1060
RC N C GHE C Y +S C EY+C D
Sbjct: 3555 KDQFRCSNGQCIPAKWKCDGHE-----DCKYGEDEKS-----CEPASPTCSSREYICASD 3604
Query: 1059 ACPFGS-KCT--YDITKPMDPITCSCE----QNAAAHNTDCSPI---------------- 949
C S KC YD D + C E Q + C PI
Sbjct: 3605 GCISASLKCNGEYDCADGSDEMDCVTECKEDQFRCKNKAHCIPIRWLCDGIHDCVDGSDE 3664
Query: 948 --CQKQPNWCH------NGGRCL-----------------DTPGYPGKCKCLPRFAGPRC 844
C++ N C N C + P K C P RC
Sbjct: 3665 ENCERGGNICRADEFLCNNSLCKLHFWVCDGEDDCGDNSDEAPDMCVKFLC-PSTRPHRC 3723
Query: 843 ---DVPVQCDDYCTNNSKCTITNGTHFECDCKPGFKGLRCEQETKCSECSNEAKCIKKP- 676
+ +Q + C +C N C K +K C+++ CSN+ KCI
Sbjct: 3724 RNNRICLQSEQMCNGIDECG-DNSDEDHCGGKLTYKARPCKKDE--FACSNK-KCIPMDL 3779
Query: 675 SGTVICQCPQGLGGEYCE-KITATSCHQ--LECKNGGYCLKPDPSANRTSPTCLCSPGFK 505
+ C G + C T +C C + YC + +TS C C PGF+
Sbjct: 3780 QCDRLDDCGDGSDEQGCRIAPTEYTCEDNVNPCGDDAYC-----NQIKTSVFCRCKPGFQ 3834
Query: 504 GLLCSSNACE--NFCLHDGNCT---LDEYFEPQCECYQAF 400
+ + CE N CL G C+ ++ +C C Q F
Sbjct: 3835 RNM-KNRQCEDLNECLVFGTCSHQCINVEGSYKCVCDQNF 3873
Score = 220 bits (560), Expect = 4e-55
Identities = 154/513 (30%), Positives = 243/513 (47%), Gaps = 17/513 (3%)
Frame = -1
Query: 5631 ASLDRQ-CKPNEWMC-DSGQCIDSGRLCDASVDCVDGSDEWVEICSLSEPPRRGCPSGWS 5458
A D+Q C P E++C D C+ LCD DC D SDE ++ C E CP
Sbjct: 25 ADRDQQLCDPGEFLCHDHVTCVSQSWLCDGDPDCPDDSDESLDTCP--EEVEIKCPLNHI 82
Query: 5457 CLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSSTRNSCDQT---WNCQRHAGF 5287
L GT C+ QLC+G DC G DE +C ++C Q + C
Sbjct: 83 ACL--GTNKCVHLSQLCNGVLDCPDGYDEGV-----HCQELLSNCQQLNCQYKCTMVRNS 135
Query: 5286 ESCSCDDGYHLSPYDKKTCLRSPSCPK-ANCSHFCIDRRDVGHQCFCAPGYILSENQKDC 5110
C C+DG+ ++ D ++C C CS C + + C C GY++ + + C
Sbjct: 136 TRCYCEDGFEITE-DGRSCKDQDECAVYGTCSQTCRNTHG-SYTCSCVEGYLMQPDNRSC 193
Query: 5109 RRN--DTIEAEILMVYGHR-LKLFTIDGHAKATLLSNLTNGV-ALDYDVKSDLVYWTDVA 4942
+ T IL++ +++F ++G ATL S N + LD+ D++ W +
Sbjct: 194 KAKIEPTDRPPILLIANFETIEVFYLNGSKMATLSSVNGNEIHTLDFIYNEDMICWIESR 253
Query: 4941 HDGNKAG---ITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMR 4771
N+ IT + + + + +A+DWL RN+Y+ D D I VC+
Sbjct: 254 ESSNQLKCIQITKAGGLTDEWTINILQSFHNVQQMAIDWLTRNLYFVDHVGDRIFVCNSN 313
Query: 4770 GRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRW 4591
G + L L++P+AI +DP+ +F+TD+G A + R +MDG N I+ +T
Sbjct: 314 GSVC-VTLIDLELHNPKAIAVDPIAGKLFFTDYGNVAKVERCDMDGMNRTRIIDSKT-EQ 371
Query: 4590 PNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRG-SVRHIFALAVFEDYVYWSDW 4414
P ALA+D + +Y+ D + DY+ +Y G R V++G VRH++ + VFEDY+Y ++
Sbjct: 372 PAALALDLVNKLVYWVDLYLDYVGVVDYQGKNRHTVIQGRQVRHLYGITVFEDYLYATNS 431
Query: 4413 HNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQ-SMGSLKTARHPCSQPARCDNL 4237
N+ I R+++ GT+ LI K G +I Q ++ S P P C ++
Sbjct: 432 DNYNIVRINRFNGTDIHSLI--KIENAWGIRIYQKRTQPTVRSHACEVDPYGMPGGCSHI 489
Query: 4236 CIPANTPDLTTSSDNFTCMCAQGFR--SEGRSC 4144
C+ L++S TC C GF S+GRSC
Sbjct: 490 CL------LSSSYKTRTCRCRTGFNLGSDGRSC 516
Score = 178 bits (452), Expect = 1e-42
Identities = 103/287 (35%), Positives = 138/287 (47%), Gaps = 46/287 (16%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADE-SNC---TCNE-NEFR 6409
+DE + C+ R C+ F+CGNG CIP +C+R +DC + DE ++C TC +F
Sbjct: 915 EDESNQTCTARTCQVDQFSCGNGRCIPRAWLCDREDDCGDQTDEMASCEFPTCEPLTQFV 974
Query: 6408 CQSGACIPSKARCNHMQDCNDASDEIGC-------PFRNCSA---------------LNE 6295
C+SG CI SK C+ DC D SDE+GC FR CS+ +
Sbjct: 975 CKSGRCISSKWHCDSDDDCGDGSDEVGCVHSCFDNQFR-CSSGRCIPGHWACDGDNDCGD 1033
Query: 6294 FGMTGLINCA------------------TTSQCIHPSWKCDGTNDCYDGSDEKDCFVEFD 6169
F INC C+ W+CDG DC DGSDEK C
Sbjct: 1034 FSDEAQINCTKEEIHSPAGCNGNEFQCHPDGNCVPDLWRCDGEKDCEDGSDEKGC----- 1088
Query: 6168 ATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADGSDEKNCDAKKCTSFEFSC 5989
G++ R CD KT+F+C +T C+ K W CDG DC D SDE +CD+ C + C
Sbjct: 1089 --NGTI---RLCDHKTKFSCWSTGRCINKAWVCDGDIDCEDQSDEDDCDSFLCGPPKHPC 1143
Query: 5988 -ESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNATFRCTNH 5851
+ C+ E+ C+G++DCPDG DE EC G C+NH
Sbjct: 1144 ANDTSVCLQPEKLCNGKKDCPDGSDEGYLCDECSLNNGG----CSNH 1186
Score = 170 bits (431), Expect = 4e-40
Identities = 126/416 (30%), Positives = 195/416 (46%), Gaps = 25/416 (6%)
Frame = -1
Query: 5313 WNCQRHAGFESCSCDDG-------------YHLSPYDKKTCLRSPSCPKAN--CSHFCID 5179
W Q A +CS DG H+ YDK+ S SC N CS C+
Sbjct: 1792 WADQNLAQLGTCSKRDGRNPTILRNKTSGVVHMKVYDKEAQQGSNSCQLNNGGCSQLCLP 1851
Query: 5178 RRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLL---SN 5008
+ C C GY L +N+ C+ IE+ ++ ++ ++ K L S
Sbjct: 1852 TSETTRTCMCTVGYYLQKNRMSCQG---IESFLMYSVHEGIRGIPLEPSDKMDALMPISG 1908
Query: 5007 LTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKG---IDGIAVD 4837
+ V +D+ ++D +YWTD+ NK S + + T++ + T G ++GIAVD
Sbjct: 1909 TSFAVGIDFHAENDTIYWTDMGF--NKI---SRAKRDQTWK--EDIITNGLGRVEGIAVD 1961
Query: 4836 WLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAH 4657
W+ NIY+TD + I V + G F +++ L+ PR+I + P + L+FWT+WG
Sbjct: 1962 WIAGNIYWTDHGFNLIEVARLNGSFRYVIIS-QGLDQPRSIAVHPEKGLLFWTEWGQMPC 2020
Query: 4656 IGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYD-GSKRRMVL 4480
IG+ +DGS E+V+L I WPN +++D +LY+ DA D I + + G R MVL
Sbjct: 2021 IGKARLDGS-EKVVLVSMGIAWPNGISIDYEENKLYWCDARTDKIERIDLETGGNREMVL 2079
Query: 4479 RGSVRHIFALAVFEDYVYWSD--WHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPS 4306
GS +F++AVF Y+YWSD N ++ R HK T + KI +
Sbjct: 2080 SGSNVDMFSVAVFGAYIYWSDRAHANGSVRRGHKNDATETITMRTGLGVNLKEVKIFN-R 2138
Query: 4305 LQSMGSLKTARHPCSQPARCDNLCIPANTPDLTTSSDNFTCMCAQGFRSE-GRSCV 4141
++ G+ AR C LC L + TC CA G+ +E G +C+
Sbjct: 2139 VREKGTNVCAR----DNGGCKQLC-------LYRGNSRRTCACAHGYLAEDGVTCL 2183
Score = 122 bits (306), Expect = 1e-25
Identities = 88/268 (32%), Positives = 117/268 (42%), Gaps = 5/268 (1%)
Frame = -1
Query: 1269 SGGAC---DGEGPLNLRCSCGDGLTGNRCQNCVGHECLNGGFCSYANSNRSLPHCICPSG 1099
SG C +G+ +N C+ D L + C+ C NGG C N L C C
Sbjct: 4190 SGATCVCPEGKYLINGTCN-DDSLLDDSCKLT----CENGGRC-ILNEKGDL-RCHCWPS 4242
Query: 1098 FTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCSCEQNAAAHNTDCSPICQKQPNWCHN 919
++G+ CE C + C G C + + TCSC N +C+ ++C N
Sbjct: 4243 YSGERCEVNHCSNYCQNGGTCVPSV---LGRPTCSCALGFTGPNCG-KTVCE---DFCQN 4295
Query: 918 GGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSKCTITNGTHFECDCKPGFKGL 739
GG C+ T G C C P + G RC V C YC N+ CTI + EC C ++G
Sbjct: 4296 GGTCIVTAGNQPYCHCQPEYTGDRCQYYV-CHHYCVNSESCTIGDDGSXECVCPTRYEGP 4354
Query: 738 RCEQETKCSECSNEAKCIKKPSGTVICQCPQGLGGEYCEKITATSCHQLE--CKNGGYCL 565
+CE + KC C I K S + C C G KI A+SC + C NGG C
Sbjct: 4355 KCEVD-KCVRCHGGHCIINKDSEDIFCNCTNG-------KI-ASSCQLCDGYCYNGGTC- 4404
Query: 564 KPDPSANRTSPTCLCSPGFKGLLCSSNA 481
+ DP N P CLCS + G C A
Sbjct: 4405 QLDPETN--VPVCLCSTNWSGTQCERPA 4430
Score = 114 bits (284), Expect = 4e-23
Identities = 72/259 (27%), Positives = 101/259 (38%), Gaps = 8/259 (3%)
Frame = -1
Query: 1134 NRSLPHCICPSG-------FTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCSCEQNAA 976
N S C+CP G D + CK C G +C I + C C + +
Sbjct: 4188 NPSGATCVCPEGKYLINGTCNDDSLLDDSCKLTCENGGRC---ILNEKGDLRCHCWPSYS 4244
Query: 975 AHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSKC 796
+ + N+C NGG C+ + C C F GP C V C+D+C N C
Sbjct: 4245 GERCEVNHCS----NYCQNGGTCVPSVLGRPTCSCALGFTGPNCGKTV-CEDFCQNGGTC 4299
Query: 795 TITNGTHFECDCKPGFKGLRCEQETKCSECSNEAKCIKKPSGTVICQCPQGLGGEYCEKI 616
+T G C C+P + G RC+ C N C G+ C CP G CE
Sbjct: 4300 IVTAGNQPYCHCQPEYTGDRCQYYVCHHYCVNSESCTIGDDGSXECVCPTRYEGPKCEVD 4359
Query: 615 TATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCLHDGNCTLD- 439
CH GG+C+ N+ S C+ + S C+ +C + G C LD
Sbjct: 4360 KCVRCH------GGHCI-----INKDSEDIFCNCTNGKIASSCQLCDGYCYNGGTCQLDP 4408
Query: 438 EYFEPQCECYQAFIGDRCQ 382
E P C C + G +C+
Sbjct: 4409 ETNVPVCLCSTNWSGTQCE 4427
Score = 111 bits (278), Expect = 2e-22
Identities = 83/358 (23%), Positives = 152/358 (42%), Gaps = 10/358 (2%)
Frame = -1
Query: 5208 KANCSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTID--- 5038
K CSH C+ + C C LS ++K C E + ++Y R ++ +D
Sbjct: 1537 KGPCSHMCLINHNRSAACACPHLMKLSSDKKTC-----YEMKKFLLYARRSEIRGVDIDN 1591
Query: 5037 ---GHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLP 4867
A + ++ + +D+D + +YWTD+ K + + + S
Sbjct: 1592 PYFNFITAFTVPDIDDVTVIDFDASEERLYWTDIKTQTIKRAFINGTG----LETVISRD 1647
Query: 4866 TKGIDGIAVDWLGRNIYYTDRNHD--AIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQA 4693
+ I G+AVDW+ RN+Y+ D I V + G ++ G ++ P+ + P++
Sbjct: 1648 IQSIRGLAVDWVSRNLYWISSEFDETQINVARLDGSLKTSIIHG--IDKPQCLAAHPVRG 1705
Query: 4692 LVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASC 4513
++WTD I NMDGSN +++ Q++ + P L++D +LY+ + I C
Sbjct: 1706 KLYWTDGNT---INMANMDGSNSKILFQNQ--KEPVGLSIDYVENKLYWISSGNGTINRC 1760
Query: 4512 NYDGSKRRMV--LRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQY 4339
N DG ++ ++ + AL + + ++W+D + + K G N +L
Sbjct: 1761 NLDGGNLEVIESMKEELTKATALTIMDKKLWWADQNLAQLGTCSKRDGRNPTIL------ 1814
Query: 4338 RPMGFKIVHPSLQSMGSLKTARHPCSQPARCDNLCIPANTPDLTTSSDNFTCMCAQGF 4165
R +VH + + + + C LC+P TS TCMC G+
Sbjct: 1815 RNKTSGVVHMKVYDKEAQQGSNSCQLNNGGCSQLCLP-------TSETTRTCMCTVGY 1865
Score = 95.1 bits (235), Expect = 2e-17
Identities = 95/424 (22%), Positives = 172/424 (40%), Gaps = 16/424 (3%)
Frame = -1
Query: 3141 VCDGRWDCADGLDESPEMCASRKARCFRIGY--CDDKKQCLDVSTALCDGIRDCFDGSDE 2968
+CDG DC D DES + C + + C +C+ +S LC+G+ DC DG DE
Sbjct: 51 LCDGDPDCPDDSDESLDTCPEEVEIKCPLNHIACLGTNKCVHLSQ-LCNGVLDCPDGYDE 109
Query: 2967 NPIHCKDMCKG------KYRCTNGRCIDVSARXXXXXXXXXXXXXXXXGAECHHFGVCAQ 2806
+HC+++ +Y+CT R EC +G C+Q
Sbjct: 110 G-VHCQELLSNCQQLNCQYKCTMVRN-STRCYCEDGFEITEDGRSCKDQDECAVYGTCSQ 167
Query: 2805 KCWMAFNHTARCHCAPGYARTKNDEN---ECEPLSKSAEMFITNGNRLHLMSLENSQVSV 2635
C + C C GY ++ + + EP + + I N + + L S+++
Sbjct: 168 TCRNTHG-SYTCSCVEGYLMQPDNRSCKAKIEPTDRPPILLIANFETIEVFYLNGSKMAT 226
Query: 2634 LRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWG----EE 2467
L V +++ + DF Y+ + + N I+ K + GL W +
Sbjct: 227 LSSVNGNEIHTL----DFIYNEDMICWIESRESSNQLKCIQITK-AGGLTDEWTINILQS 281
Query: 2466 ESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSL 2287
+ D++ N+YF + + DR I+V + + TLI ++
Sbjct: 282 FHNVQQMAIDWLTRNLYFVDH-------VGDR---IFVCNSNGSVCVTLIDLELHNPKAI 331
Query: 2286 AVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFS 2107
AVDPI +F+T V ++ ++DG +++ +P ++ LD
Sbjct: 332 AVDPIAGKLFFTDYGNVAKVERCDMDG-----------MNRTRIIDSKTEQPAALALDLV 380
Query: 2106 NERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITRQG-SIHRMH 1930
N+ +YW+D+ + V + G++R TV + + V Y+Y +I R++
Sbjct: 381 NKLVYWVDLYLDYVGVVDYQGKNRHTVIQGRQVRHLYGITVFEDYLYATNSDNYNIVRIN 440
Query: 1929 KFTG 1918
+F G
Sbjct: 441 RFNG 444
Score = 92.4 bits (228), Expect = 1e-16
Identities = 187/834 (22%), Positives = 290/834 (34%), Gaps = 99/834 (11%)
Frame = -1
Query: 2820 GVCAQKCWMAFNHTAR-CHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLE-NS 2647
G C+ C ++ ++ R C C G+ +D C+ +F G + ++ N+
Sbjct: 484 GGCSHICLLSSSYKTRTCRCRTGF-NLGSDGRSCKRPKNELFLFYGKGRPGIVRGMDLNT 542
Query: 2646 QVS--VLRPVFNIKMNLIPGGIDF----GYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLI 2485
+++ + P+ N+ + P +DF Y F T + +G R D L
Sbjct: 543 KIADEYMIPIENL---VNPRALDFHAETNYIYFADTTSFLIGRQKIDGTERETILKDDLD 599
Query: 2484 GSWGEEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNST 2305
G I D++ NN+Y+T + + N+ + S +TL+
Sbjct: 600 NVEG--------IAVDWIGNNLYWTNDGHR-------KTINVARLEKASQSRKTLLEGEM 644
Query: 2304 GTINSLAVDPIKRLIFWTT------SAPVPRILSANLDGKPIAQPFKTGSQPHKALVERN 2143
+ VDP+ ++WT V RI A +DG + V
Sbjct: 645 SHPRGIVVDPVNGWMYWTDWEEDEIDDSVGRIEKAWMDGFN-----------RQIFVTSK 693
Query: 2142 IFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYL 1963
+ P + LDF LYW D IE V +G R+ V + P + G Y++
Sbjct: 694 MLWPNGLTLDFHTNTLYWCDAYYDHIEKVFLNGTHRKIVYSGRELNHPFGLSHHGNYVFW 753
Query: 1962 IT-RQGSIHRMHKFTGKTNKYVQKIR-EVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYC 1789
GSI ++ T + V +R E P +++ P K ++ N S C
Sbjct: 754 TDYMNGSIFQLDLITSE----VTLLRHERPPLFGLQIYDPRKQQGDNMCRVNNGGCSTLC 809
Query: 1788 ---PSNTVCVPDQ----DKNGILIPKCLCGPGRF---------FEVSTKKCMQLREKDQE 1657
P VC D+NG C PG F + C+Q R K
Sbjct: 810 LAIPGGRVCACADNQLLDENG---TTCTFNPGEALPHICKAGEFRCKNRHCIQARWKCDG 866
Query: 1656 ASQCGD------YFCYNNAGCSPQKTCV---CPPGFY----GRQCEIN--ECSETCWNGE 1522
C D C+N++ Q C C P + C N E ++TC
Sbjct: 867 DDDCLDGSDEDSVNCFNHSCPDDQFKCQNNRCIPKRWLCDGANDCGSNEDESNQTC-TAR 925
Query: 1521 TCAVQEFGSTTNVVC-----------HCPSNYTQ-SSCATNVCEGVCGPRGSCKTVPCPK 1378
TC V +F S N C C + +SC CE + + CK+ C
Sbjct: 926 TCQVDQF-SCGNGRCIPRAWLCDREDDCGDQTDEMASCEFPTCEPL--TQFVCKSGRCIS 982
Query: 1377 DEPHCRSYSFCECDKGWTGPHCRHKA---DAKVCYGHCFSG-GACDGEGPLNLRCSCGDG 1210
+ HC S +C G C H + G C G ACDG+ CGD
Sbjct: 983 SKWHCDSDD--DCGDGSDEVGCVHSCFDNQFRCSSGRCIPGHWACDGDN------DCGD- 1033
Query: 1209 LTGNRCQNCVGHECLNGGFCSYANSNRSLP--HCI-----------CPSGFTGDHCE--- 1078
+ NC E + C+ N + P +C+ C G C
Sbjct: 1034 FSDEAQINCTKEEIHSPAGCN-GNEFQCHPDGNCVPDLWRCDGEKDCEDGSDEKGCNGTI 1092
Query: 1077 ---EYLCKDACPFGSKCTYDITKPMDPITCSCEQNAAAHNTDC-SPICQKQPNWCHNG-G 913
++ K +C +C I C + + DC S +C + C N
Sbjct: 1093 RLCDHKTKFSCWSTGRCINKAWVCDGDIDCEDQSD----EDDCDSFLCGPPKHPCANDTS 1148
Query: 912 RCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNN----SKCTITNGTHFECDCKPGFK 745
CL P K + D CD+ NN + C++ G C C +
Sbjct: 1149 VCLQ----PEKLCNGKKDCPDGSDEGYLCDECSLNNGGCSNHCSVVPGRGIVCSCP---E 1201
Query: 744 GLRCEQETKCSE----CSNEAKC---IKKPSGTVICQCPQG----LGGEYCEKI 616
GL+ ++ K E CSN KC ++ TV C C +G + GE C +
Sbjct: 1202 GLQLNKDNKTCEIVDYCSNHLKCSQVCEQHKHTVKCSCYEGWKLDVDGESCTSV 1255
Score = 89.7 bits (221), Expect = 8e-16
Identities = 91/411 (22%), Positives = 133/411 (32%), Gaps = 97/411 (23%)
Frame = -1
Query: 6051 ADGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGED-----EHQCETECDS 5887
A +D +C+ C C P +GR +C D +++C T+ S
Sbjct: 2455 AVANDTNSCELSPCALLNGGCHDLCLLTP-----NGRVNCSCRGDRILLEDNRCVTKNSS 2509
Query: 5886 KGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSL-------------------------- 5785
+ F C N CI CDG C D +
Sbjct: 2510 CNAYSEFECGNGECIDYQLTCDGIPHCKDKSDEKLLYCENRSCRRGFKPCYNRRCIPHGK 2569
Query: 5784 ----------GSDEVDCAAGRTSFHVPSRCADETCV------------------------ 5707
SDE+DC T V RCAD TC+
Sbjct: 2570 LCDGENDCGDNSDELDCKVS-TCATVEFRCADGTCIPRSARCNQNIDCADASDEKNCNNT 2628
Query: 5706 ---------------VACELTAV------LCDGIQDCSDGFDEKNCASLDR-QCKPNEWM 5593
+ C T++ +CDG DC D DE C ++ +C+ N +
Sbjct: 2629 DCTHFYKLGVKTTGFIRCNSTSLCVLPTWICDGSNDCGDYSDELKCPVQNKHKCEENYFS 2688
Query: 5592 CDSGQCIDSGRLCDASVDCVDGSDEWVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQ 5413
C SG+CI + +CD DC DG DE+ C S W+ + C+ +
Sbjct: 2689 CPSGRCILNTWICDGQKDCEDGRDEF--HCDSS--------CSWNQFACSAQ-KCISKHW 2737
Query: 5412 LCDGRRDCMSGIDEQ--------CDNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYH 5257
+CDG DC G+DE C +C +R + W C C DG
Sbjct: 2738 ICDGEDDCGDGLDESDSICGAITCAADMFSCQGSRACVPRHWLCDGER-----DCPDG-- 2790
Query: 5256 LSPYDKKTCLRSPSCPKANC--SHFCIDRRDVGHQCFCAPGYILSENQKDC 5110
S A C ++ C + + H C P + ++ DC
Sbjct: 2791 -----------SDELSTAGCAPNNTCDENAFMCHNKVCIPKQFVCDHDDDC 2830
Score = 86.3 bits (212), Expect = 9e-15
Identities = 44/121 (36%), Positives = 57/121 (46%)
Frame = -1
Query: 708 CSNEAKCIKKPSGTVICQCPQGLGGEYCEKITATSCHQLECKNGGYCLKPDPSANRTSPT 529
C N +CI G + C C GE CE C C+NGG C+ PS PT
Sbjct: 4221 CENGGRCILNEKGDLRCHCWPSYSGERCE---VNHCSNY-CQNGGTCV---PSV-LGRPT 4272
Query: 528 CLCSPGFKGLLCSSNACENFCLHDGNCTLDEYFEPQCECYQAFIGDRCQYRIHQHAVIFS 349
C C+ GF G C CE+FC + G C + +P C C + GDRCQY + H + S
Sbjct: 4273 CSCALGFTGPNCGKTVCEDFCQNGGTCIVTAGNQPYCHCQPEYTGDRCQYYVCHHYCVNS 4332
Query: 348 D 346
+
Sbjct: 4333 E 4333
Score = 73.6 bits (179), Expect = 6e-11
Identities = 47/138 (34%), Positives = 63/138 (45%), Gaps = 7/138 (5%)
Frame = -1
Query: 6165 TGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADGSDEK--NCDAK---KCTSF 6001
T G+ + CD +F C TC+ + W CDG PDC D SDE C + KC
Sbjct: 22 TVGADRDQQLCDPG-EFLCHDHVTCVSQSWLCDGDPDCPDDSDESLDTCPEEVEIKCPLN 80
Query: 6000 EFSCESSKKCIPLEQKCDGRRDCPDGEDE--HQCETECDSKGGNATFRCTNHRCIPMAWR 5827
+C + KC+ L Q C+G DCPDG DE H E + + N ++CT R +
Sbjct: 81 HIACLGTNKCVHLSQLCNGVLDCPDGYDEGVHCQELLSNCQQLNCQYKCTMVRNSTRCYC 140
Query: 5826 CDGTDDCMDNAKSLGSDE 5773
DG + D DE
Sbjct: 141 EDGFEITEDGRSCKDQDE 158
Score = 71.2 bits (173), Expect = 3e-10
Identities = 79/307 (25%), Positives = 119/307 (38%), Gaps = 9/307 (2%)
Frame = -1
Query: 2820 GVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENS-Q 2644
G C+Q C T C C GY KN C+ + + G R + LE S +
Sbjct: 1843 GGCSQLCLPTSETTRTCMCTVGYYLQKN-RMSCQGIESFLMYSVHEGIRG--IPLEPSDK 1899
Query: 2643 VSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEE 2464
+ L P+ + GIDF + +Y +G +++ R+K+ +W E+
Sbjct: 1900 MDALMPISGTSFAV---GIDFHAE---NDTIYWTDMGFNKIS-RAKRDQ-----TWKEDI 1947
Query: 2463 STAGL-----ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGT 2299
T GL I D++ N+Y+T+ I VA+ + +I
Sbjct: 1948 ITNGLGRVEGIAVDWIAGNIYWTDHGFNL----------IEVARLNGSFRYVIISQGLDQ 1997
Query: 2298 INSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMV 2119
S+AV P K L+FWT +P I A LDG LV I P +
Sbjct: 1998 PRSIAVHPEKGLLFWTEWGQMPCIGKARLDG-----------SEKVVLVSMGIAWPNGIS 2046
Query: 2118 LDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITR---QG 1948
+D+ +LYW D IE + + R + ++ V G YIY R G
Sbjct: 2047 IDYEENKLYWCDARTDKIERIDLETGGNREMVLSGSNVDMFSVAVFGAYIYWSDRAHANG 2106
Query: 1947 SIHRMHK 1927
S+ R HK
Sbjct: 2107 SVRRGHK 2113
Score = 62.0 bits (149), Expect = 2e-07
Identities = 56/186 (30%), Positives = 75/186 (40%), Gaps = 17/186 (9%)
Frame = -1
Query: 3858 CTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDEL------NCEITSCKPDFFACFNGTAI 3697
C +F C D C+ + +CD + DC D SDE EI C + AC GT
Sbjct: 32 CDPGEFLCHDHVTCVSQSWLCDGDPDCPDDSDESLDTCPEEVEI-KCPLNHIACL-GT-- 87
Query: 3696 SKCIPKEFYCDGEDDCPEGQDEPDSCFG-IGECTHEQFQCTSGKCIPKRRQCDGTLDCRD 3520
+KC+ C+G DCP+G DE C + C +Q C KC R C D
Sbjct: 88 NKCVHLSQLCNGVLDCPDGYDEGVHCQELLSNC--QQLNC-QYKCTMVRNST--RCYCED 142
Query: 3519 G----SDEKGCK--KECAI--VCDNSC--VHADDLCDGKKKCNDGSDEDEEACVIKQLLE 3370
G D + CK ECA+ C +C H C +CV L++
Sbjct: 143 GFEITEDGRSCKDQDECAVYGTCSQTCRNTHGSYTC---------------SCVEGYLMQ 187
Query: 3369 KENRKC 3352
+NR C
Sbjct: 188 PDNRSC 193
Score = 58.2 bits (139), Expect = 3e-06
Identities = 49/186 (26%), Positives = 73/186 (38%), Gaps = 26/186 (13%)
Frame = -1
Query: 3999 CIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCEN---FECTEAQFKCGD 3829
C G+F+C + C+ S LCDG DC DE C +C C
Sbjct: 32 CDPGEFLC-----HDHVTCVSQSWLCDGDPDCPDDSDESLDTCPEEVEIKCPLNHIACLG 86
Query: 3828 KKKCIPLTSVCDKEKDCDDGSDE--------LNCEITSCKPDFFACFNGTAISKCIPKEF 3673
KC+ L+ +C+ DC DG DE NC+ +C+ + C ++C
Sbjct: 87 TNKCVHLSQLCNGVLDCPDGYDEGVHCQELLSNCQQLNCQ---YKCTMVRNSTRC----- 138
Query: 3672 YC-DGEDDCPEGQD--EPDSCFGIGEC------THEQFQCTSGKCI------PKRRQCDG 3538
YC DG + +G+ + D C G C TH + C+ C+ P R C
Sbjct: 139 YCEDGFEITEDGRSCKDQDECAVYGTCSQTCRNTHGSYTCS---CVEGYLMQPDNRSCKA 195
Query: 3537 TLDCRD 3520
++ D
Sbjct: 196 KIEPTD 201
Score = 57.8 bits (138), Expect = 4e-06
Identities = 83/400 (20%), Positives = 148/400 (36%), Gaps = 21/400 (5%)
Frame = -1
Query: 2820 GVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQV 2641
G C+ C + N +A C C P + +D+ C + K F+ R + V
Sbjct: 1538 GPCSHMCLINHNRSAACAC-PHLMKLSSDKKTCYEMKK----FLLYARRSEIRG-----V 1587
Query: 2640 SVLRPVFNIKMNLIPGGID----FGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWG 2473
+ P FN ID +D L +T DI+++ I G
Sbjct: 1588 DIDNPYFNFITAFTVPDIDDVTVIDFDASEERLYWT--------DIKTQTIKRAFINGTG 1639
Query: 2472 EE-------ESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIV 2314
E +S GL D++ N+Y+ S FD + I VA+ D S +T I+
Sbjct: 1640 LETVISRDIQSIRGLAV-DWVSRNLYWISSE-------FD-ETQINVARL-DGSLKTSII 1689
Query: 2313 NSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFE 2134
+ LA P++ ++WT + AN+DG + ++ +N E
Sbjct: 1690 HGIDKPQCLAAHPVRGKLYWTDGNTINM---ANMDGS------------NSKILFQNQKE 1734
Query: 2133 PTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITR 1954
P + +D+ +LYWI TI + DG + ++V+ +T+
Sbjct: 1735 PVGLSIDYVENKLYWISSGNGTINRCNLDGGN---------------LEVIESMKEELTK 1779
Query: 1953 QGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQK----------NPC 1804
++ M K ++ + ++ S R R ++ S + H K N C
Sbjct: 1780 ATALTIMDKKLWWADQNLAQLGTCSKR-DGRNPTILRNKTSGVVHMKVYDKEAQQGSNSC 1838
Query: 1803 QSDYCPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKC 1684
Q + + +C+P + C+C G + + + C
Sbjct: 1839 QLNNGGCSQLCLPTSETT----RTCMCTVGYYLQKNRMSC 1874
Score = 50.8 bits (120), Expect = 4e-04
Identities = 35/127 (27%), Positives = 50/127 (38%), Gaps = 16/127 (12%)
Frame = -1
Query: 5868 FRCTNH-RCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACEL 5692
F C +H C+ +W CDG DC D++ + +D P C
Sbjct: 37 FLCHDHVTCVSQSWLCDGDPDCPDDS----DESLDTCPEEVEIKCPLNHIACLGTNKCVH 92
Query: 5691 TAVLCDGIQDCSDGFDE--------KNCASLDRQCK----PNEWMC---DSGQCIDSGRL 5557
+ LC+G+ DC DG+DE NC L+ Q K N C D + + GR
Sbjct: 93 LSQLCNGVLDCPDGYDEGVHCQELLSNCQQLNCQYKCTMVRNSTRCYCEDGFEITEDGRS 152
Query: 5556 CDASVDC 5536
C +C
Sbjct: 153 CKDQDEC 159
Score = 48.9 bits (115), Expect = 0.002
Identities = 53/197 (26%), Positives = 78/197 (38%), Gaps = 21/197 (10%)
Frame = -1
Query: 6543 RVCRPGYFNCGNGL-CIPEQKVCNRINDCANFADESNCTCNEN-EFRCQ--------SGA 6394
++C PG F C + + C+ + +C+ DC + +DES TC E E +C +
Sbjct: 30 QLCDPGEFLCHDHVTCVSQSWLCDGDPDCPDDSDESLDTCPEEVEIKCPLNHIACLGTNK 89
Query: 6393 CIPSKARCNHMQDCNDASDE-IGCP--FRNCSALNEFGMTGLINCATTSQCIHPSWKCDG 6223
C+ CN + DC D DE + C NC L NC + S +C
Sbjct: 90 CVHLSQLCNGVLDCPDGYDEGVHCQELLSNCQQL---------NCQYKCTMVRNSTRC-- 138
Query: 6222 TNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLAT--RTCMPKH--WQCDGQPD 6055
C DG F+ T RSC + + A T +TC H + C
Sbjct: 139 --YCEDG---------FEITEDG----RSCKDQDECAVYGTCSQTCRNTHGSYTC----S 179
Query: 6054 CADG----SDEKNCDAK 6016
C +G D ++C AK
Sbjct: 180 CVEGYLMQPDNRSCKAK 196
Score = 48.5 bits (114), Expect = 0.002
Identities = 31/97 (31%), Positives = 39/97 (39%), Gaps = 11/97 (11%)
Frame = -1
Query: 6450 ADESNCTCNENEFRCQSGA-CIPSKARCNHMQDCNDASDE----------IGCPFRNCSA 6304
AD C+ EF C C+ C+ DC D SDE I CP +
Sbjct: 25 ADRDQQLCDPGEFLCHDHVTCVSQSWLCDGDPDCPDDSDESLDTCPEEVEIKCPLNH--- 81
Query: 6303 LNEFGMTGLINCATTSQCIHPSWKCDGTNDCYDGSDE 6193
I C T++C+H S C+G DC DG DE
Sbjct: 82 ---------IACLGTNKCVHLSQLCNGVLDCPDGYDE 109
Score = 45.1 bits (105), Expect = 0.024
Identities = 66/262 (25%), Positives = 91/262 (34%), Gaps = 37/262 (14%)
Frame = -1
Query: 1632 CYNNAGCSPQKTCVCPPGFYGRQCEINECSETCWNG-ETCAVQEFGSTTNVVCHCPSNYT 1456
C N A C P + +C G + C E C G C EF +C+
Sbjct: 3639 CKNKAHCIPIRW-LCD-GIH--DCVDGSDEENCERGGNICRADEF------LCN------ 3682
Query: 1455 QSSCATN--VCEGV--CGPRGS-----CKTVPCPKDEPH-CRSYSFC-----------EC 1339
S C + VC+G CG C CP PH CR+ C EC
Sbjct: 3683 NSLCKLHFWVCDGEDDCGDNSDEAPDMCVKFLCPSTRPHRCRNNRICLQSEQMCNGIDEC 3742
Query: 1338 DKGWTGPHCRHKAD--AKVCYGHCFSGGACDGEG--PLNLRCS----CGDGLTGNRCQNC 1183
HC K A+ C F AC + P++L+C CGDG C+
Sbjct: 3743 GDNSDEDHCGGKLTYKARPCKKDEF---ACSNKKCIPMDLQCDRLDDCGDGSDEQGCRIA 3799
Query: 1182 -VGHECLNG----GFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDA--CPFGSKCTYDI 1024
+ C + G +Y N ++ C C GF + + C+D C C++
Sbjct: 3800 PTEYTCEDNVNPCGDDAYCNQIKTSVFCRCKPGFQRN-MKNRQCEDLNECLVFGTCSHQC 3858
Query: 1023 TKPMDPITCSCEQNAAAHNTDC 958
C C+QN N C
Sbjct: 3859 INVEGSYKCVCDQNFQERNNTC 3880
Score = 43.5 bits (101), Expect = 0.069
Identities = 35/116 (30%), Positives = 45/116 (38%), Gaps = 27/116 (23%)
Frame = -1
Query: 3468 SCVHADDLCDGKKKCNDGSDED--------EEACVIKQLLEKENRKCGGFA--CDGIVDC 3319
+CV LCDG C D SDE E C + + KC + C+G++DC
Sbjct: 44 TCVSQSWLCDGDPDCPDDSDESLDTCPEEVEIKCPLNHIACLGTNKCVHLSQLCNGVLDC 103
Query: 3318 EDGSDE--------KGCPDLECHLA------SNKSLICDG---TIDCSSGKDENNC 3202
DG DE C L C S + DG T D S KD++ C
Sbjct: 104 PDGYDEGVHCQELLSNCQQLNCQYKCTMVRNSTRCYCEDGFEITEDGRSCKDQDEC 159
>gi|47228669|emb|CAG07401.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 2378
Score = 771 bits (1990), Expect = 0.0
Identities = 619/2132 (29%), Positives = 873/2132 (40%), Gaps = 237/2132 (11%)
Frame = -1
Query: 6522 FNCGNGLCIPEQKVCNRINDCANFADE-----SNCTCNENEFRCQSGACIPSKARCNHMQ 6358
F CGNG CI C+ + C + +DE +N C + RC +G CI + C+
Sbjct: 265 FECGNGDCINYSLTCDGMAHCKDKSDEKQSYCANRICKKGYRRCINGRCIGHQFWCDGTD 324
Query: 6357 DCNDASDEIGCP-----FRNCSALNEFGMTGLINCATTSQ-------CIHPSWKCDGTND 6214
DC D SDE+ C N F L+ + CI +CD +
Sbjct: 325 DCGDHSDELPCNTLLVLISQGLLPNWFAFLLLVTLCKPGEFQCKDGSCISNFSRCDQVVN 384
Query: 6213 CYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADGSDE 6034
C D SDE +C +T S + +C T C W CDG DC D SDE
Sbjct: 385 CEDASDEMNC----QSTDCSRFFRLGVKGASFQSCERTTLCYLSSWVCDGNNDCGDFSDE 440
Query: 6033 KNCDAK---KCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNATFR 5863
KNC K KC F+C S + CIP+ CD DC +G DE C+ C S F
Sbjct: 441 KNCPDKRKLKCPVNFFACPSGR-CIPMSWTCDKENDCENGADETHCDKFCTS----TQFE 495
Query: 5862 CTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACELTAV 5683
C NHRCI W CDG+DDC D GSDE +T +C C
Sbjct: 496 CANHRCISSHWVCDGSDDCGD-----GSDEDQKCKSKTCSPEAFQCPGSHM---CVPQRW 547
Query: 5682 LCDGIQDCSDGFDEK---NCASLDRQCKP-NEWMCDSGQCIDSGRLCDASVDCVDGSDEW 5515
CDG +DC DG DE C + C P NE+MC + QCI +CD VDC DGSDE
Sbjct: 548 KCDGDKDCPDGADESVKAGCMYTNSTCDPENEFMCQNRQCIPKHFVCDLDVDCSDGSDES 607
Query: 5514 VEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQL-CDGRRDCMSGIDEQCDNPQGNCSS 5338
E E P G P + C NG CL +++ CDG DC DE NP+ C+S
Sbjct: 608 PEC----EYPTCG-PDEFRC--ANGR--CLNQKKWECDGEFDCHDHSDEAPKNPR--CTS 656
Query: 5337 TRNSCDQT------WNCQRHAGF--ESCSCDDGYHLSPYDKKTCLRSPSCPKANCSHFCI 5182
+ +C+ + NC + C DG CL S + CS C
Sbjct: 657 SERTCNDSAFTCLNGNCLNETLLCDRNDDCGDGSDELNCFINECLNSKL---SGCSQLCD 713
Query: 5181 DRRDVGHQCFCAPGYILSENQKDCRRNDTI---------------------------EAE 5083
D + +G++C C PG+ L + K C D + E
Sbjct: 714 DLK-IGYKCRCHPGFQLKRDGKTCVDVDECLTTYPCSQRCINTHGSFHCLCVDGFQPKEE 772
Query: 5082 ILMVYGHR--LKLFTIDGHAKATLLSN-----------------------------LTNG 4996
+++ +R L+ +DG + TL+ L N
Sbjct: 773 PYLIFANRYYLRKLNLDG-SNYTLIKQVRSAPAETMRWSSLLGPCARFNPFRHFQGLNNA 831
Query: 4995 VALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIY 4816
VALD+ ++YWTDV G+ I M + V++ DG+AVDW+G N+Y
Sbjct: 832 VALDFHYAEQMIYWTDVTTQGSM--IRRMHMNGSNMEVLHRTSLSNPDGLAVDWVGGNLY 889
Query: 4815 YTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMD 4636
+ D+ D I V + G + +L+ + L +PRA+ +D ++W+DWG + HIGR+ MD
Sbjct: 890 WCDKGRDTIEVSKLNGAYRTVLVN-SGLREPRALAVDVRYRYLYWSDWGDNPHIGRIGMD 948
Query: 4635 GSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIF 4456
GSN VI++++ I WPN L +D R+Y+ DA DYI + DG+ R VL + HIF
Sbjct: 949 GSNRSVIVEEK-ITWPNGLTLDFINDRIYWADAREDYIEFASLDGTNRHTVLNHDIPHIF 1007
Query: 4455 ALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTA 4276
A+ +FE+Y+YW+DW +I R HK GTN+ LI +RPM I HP Q +
Sbjct: 1008 AMTLFEEYIYWTDWETKSINRAHKTQGTNKTTLI-STLHRPMDVHIYHPYRQP----EVL 1062
Query: 4275 RHPC-SQPARCDNLCIPANTPDLTTSSDNFTCMCAQGF--RSEGRSCVSECKPNDFVCTK 4105
HPC + C NLC L + + C C F S+ R+C+S C + FVC K
Sbjct: 1063 NHPCQTNNGGCSNLC-------LLSPGGGYKCACPTNFYLASDQRTCMSNCTASQFVC-K 1114
Query: 4104 TYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKL 3925
KCI WW+ CP F C GQF CG T C + +
Sbjct: 1115 NDKCIPFWWKCDTEDDCGDRSDE----PADCPEFKCRPGQFQCG------TGICTNPAYI 1164
Query: 3924 CDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEI 3745
CDG DC DE A C+ C +QFKC +CIP C+ + +C DG DE +C
Sbjct: 1165 CDGDNDCQDNSDE--ANCDIHVCLPSQFKCSHPSRCIPGIFRCNGQDNCGDGEDEKDCPE 1222
Query: 3744 TSCKPDFFACFNGTAISK-CIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQC-TSG 3571
+C P F C AI+K CIP+ + CD ++DC +G DEP +C + C ++F+C SG
Sbjct: 1223 VTCAPTQFQC----AITKRCIPRVWVCDRDNDCVDGSDEPANCTQM-TCGVDEFRCKDSG 1277
Query: 3570 KCIPKRRQCDGTLDCRDGSDEKGCKKECA-IVCD--------NSCVHADDLCDGKKKCND 3418
+CIP R +CDG DC D SDE K+ECA C+ N CV CD C D
Sbjct: 1278 RCIPARWKCDGEDDCGDASDEP--KEECAERTCEPYQFRCKNNRCVPGRWQCDYDNDCGD 1335
Query: 3417 GSDEDEEACVIKQLLEKE----NRKC--GGFACDGIVDCEDGSDEKGCPDLEC---HLAS 3265
SDED+ C+ +Q E E N +C G + CDG DC DGSDE GC DL+C H
Sbjct: 1336 NSDEDK--CMPRQCSESEFACTNGRCIAGRWKCDGDHDCADGSDEHGC-DLKCDTDHFQC 1392
Query: 3264 NKSLI------CDGTIDCSSGKDENNCHNNGE----SNFFQCSMQTIK--EWQVCDGRWD 3121
N CD DC G DE NC + E ++ FQC+ K W+ CDG D
Sbjct: 1393 NNGHCIPIRWRCDADPDCLDGSDEENCGSATERHCPADEFQCNNTLCKPLAWK-CDGEDD 1451
Query: 3120 CADGLDESPEMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDE-------NP 2962
C D DE+PE C + R C + + CL VS CDG+ +C D SDE P
Sbjct: 1452 CGDNSDENPEQCRKFQCPPTRAFRCQNDRVCLQVSKR-CDGVNNCGDNSDELNCRTCWTP 1510
Query: 2961 IHCKDMC------------------------KGKYRCTNGRCIDVSAR------XXXXXX 2872
++C K ++ C N RCI + R
Sbjct: 1511 SCSYEICAFLDCKRNICCASTETPPAVPTCEKDEFLCANHRCISSTLRCNLFNDCEDFGS 1570
Query: 2871 XXXXXXXXXXGAECH----HFGVCAQKCWMAFNHTARCHCAPGYA----RTKNDENECEP 2716
+C H G + + + C C PG+ RT D+NEC
Sbjct: 1571 DEIGCKTDTKLNDCRSNRTHCGDGDEAHCVTNGTDSFCSCKPGFQKIGHRTCGDKNECLQ 1630
Query: 2715 LSKSA---------------EMFITNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDF 2581
+ + F + ++ +S+ + N +L PG D+
Sbjct: 1631 FGVCSHSCNNTKGSYKCSCHKYFTRISDTCKADNINSSRQILYIADDNEIRSLDPGMPDW 1690
Query: 2580 GYDVFRTTLMYTVGIGNSRVDIRSK-------KWSDGLIGSW---------------GEE 2467
Y+ T + +D+ K W G I ++
Sbjct: 1691 RYE---QTFQGDASVRIDAMDVHVKTNRIFWTNWHTGRISTYELQGPSLSATSSNSHRHR 1747
Query: 2466 ESTAGLIT--------------YDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTST 2329
+ G +T D++ N+Y+T+S I VA+ +
Sbjct: 1748 RQSEGRVTDLQIKELKMPRGIAVDWVAGNLYWTDSGRD----------VIEVAQMSGQNC 1797
Query: 2328 RTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVE 2149
+TLI ++ V+P + ++W P+I +A +DG + LV
Sbjct: 1798 KTLISGMIDEPYAIVVNPQRGTMYWADWGNHPKIETAAMDG-----------TLRQTLVH 1846
Query: 2148 RNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDT---PVTMDVLG 1978
NI PT + +D+ NERLYW D I +V DG D + L + P ++D+
Sbjct: 1847 ENIQWPTGLAVDYFNERLYWADAKLSVIGSVRLDGSD-PVISVSGLKNNLLHPFSIDIFE 1905
Query: 1977 GYIYLITRQGSI-HRMHKF-TGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPC 1804
YIY +T +I R++KF GK I S I + H K NPC
Sbjct: 1906 DYIYGVTYINNIVFRVNKFGKGKMENLTTGINHAS---DIVLHHRYKQ-----PEMTNPC 1957
Query: 1803 QSDYCPSNTVCVPDQDKNGILIPKCLCGPGRFFE---VSTKKCMQLREKDQEASQCGDYF 1633
C + P P C C P ++ +K + + S+ D
Sbjct: 1958 DRKKCEWLCLLSPSG-------PVCTC-PNKYVADNGTCVEKPVPTQSPFSPPSEPCDIQ 2009
Query: 1632 CYNNAGC----SPQKTCVCPPGFYGRQCEINECSETCWNGETCAVQEFGSTTNVVCHCPS 1465
C N C C C P + G +CEIN+C + C NG TC G T C CP
Sbjct: 2010 CLNGGSCFLNARQVAKCRCQPSYIGERCEINQCRDYCKNGGTCTASHAGVPT---CRCPK 2066
Query: 1464 NYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHKADAKVC 1285
+T +C+ C+ C GSC + C C + G C++ C
Sbjct: 2067 GFTGPTCSRQTCQDYCQNGGSCSV--------SMGNQPTCSCPSEYQGDRCQY----TTC 2114
Query: 1284 YGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQNCVGHECLNGGFCSYANSNRSLPHCI-C 1108
G C + G C C C + G++C+ C G + +S + + +
Sbjct: 2115 EGFCHNSGTCLQTSNGTKLCLCSNQYVGHQCELDKCQFCGTGKCFTSPSSEVTCRYVLGM 2174
Query: 1107 PS--GFTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCSCEQNAAAHNTDCSPICQKQP 934
P+ +T C ++ A CSC N P C
Sbjct: 2175 PTVLPWTAFLCSLFISNTA-------------------CSCP------NGQIQPSCFTCL 2209
Query: 933 NWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDV 838
N+C G +D+ +CKC ++G C++
Sbjct: 2210 NYCSRGQCSVDSRTLLPQCKCPAGWSGYTCEI 2241
Score = 355 bits (910), Expect = 1e-95
Identities = 269/905 (29%), Positives = 388/905 (42%), Gaps = 96/905 (10%)
Frame = -1
Query: 6552 CSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC---TCNENEFRCQSGA-CIP 6385
C CRPG F CG G+C +C+ NDC + +DE+NC C ++F+C + CIP
Sbjct: 1141 CPEFKCRPGQFQCGTGICTNPAYICDGDNDCQDNSDEANCDIHVCLPSQFKCSHPSRCIP 1200
Query: 6384 SKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDGTNDCYD 6205
RCN +C D DE CP C+ CA T +CI W CD NDC D
Sbjct: 1201 GIFRCNGQDNCGDGEDEKDCPEVTCAPTQ-------FQCAITKRCIPRVWVCDRDNDCVD 1253
Query: 6204 GSDE----------------KD----------CFVEFDATGGSVSAPRSCDAKT----QF 6115
GSDE KD C E D S C +T QF
Sbjct: 1254 GSDEPANCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDASDEPKEECAERTCEPYQF 1313
Query: 6114 ACLATRTCMPKHWQCDGQPDCADGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRD 5935
C R C+P WQCD DC D SDE C ++C+ EF+C + + CI KCDG D
Sbjct: 1314 RCKNNR-CVPGRWQCDYDNDCGDNSDEDKCMPRQCSESEFACTNGR-CIAGRWKCDGDHD 1371
Query: 5934 CPDGEDEHQCETECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAG 5755
C DG DEH C+ +CD+ F+C N CIP+ WRCD DC+D GSDE +C +
Sbjct: 1372 CADGSDEHGCDLKCDTDH----FQCNNGHCIPIRWRCDADPDCLD-----GSDEENCGSA 1422
Query: 5754 RTSFHVPSRCADETCV--VACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNE-WMCDS 5584
T H P ADE C+ A CDG DC D DE QC P + C +
Sbjct: 1423 -TERHCP---ADEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEQCRKFQCPPTRAFRCQN 1478
Query: 5583 GQ-CIDSGRLCDASVDCVDGSDE------WVEICSLSEPPRRGCPSGWSCLLTN---GTI 5434
+ C+ + CD +C D SDE W CS C C T
Sbjct: 1479 DRVCLQVSKRCDGVNNCGDNSDELNCRTCWTPSCSYEICAFLDCKRNICCASTETPPAVP 1538
Query: 5433 GCLQEQQLCDGRR------------DCMS-GIDE---QCDNPQGNCSSTRNSCDQ--TWN 5308
C +++ LC R DC G DE + D +C S R C +
Sbjct: 1539 TCEKDEFLCANHRCISSTLRCNLFNDCEDFGSDEIGCKTDTKLNDCRSNRTHCGDGDEAH 1598
Query: 5307 CQRHAGFESCSCDDGY----HLSPYDKKTCLRSPSCPKANCSHFCIDRRDVGHQCFCAPG 5140
C + CSC G+ H + DK CL+ CSH C + + ++C C
Sbjct: 1599 CVTNGTDSFCSCKPGFQKIGHRTCGDKNECLQF-----GVCSHSCNNTKG-SYKCSCHKY 1652
Query: 5139 YILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLTNGVA------LDYD 4978
+ + C+ ++ + ++ ++ ++D G A +D
Sbjct: 1653 F--TRISDTCKADNINSSRQILYIADDNEIRSLDPGMPDWRYEQTFQGDASVRIDAMDVH 1710
Query: 4977 VKSDLVYWTDVAHDGNKA-----GITSMSNQPNTYRV-------INSLPTKGID---GIA 4843
VK++ ++WT+ H G + G + + N++R + L K + GIA
Sbjct: 1711 VKTNRIFWTNW-HTGRISTYELQGPSLSATSSNSHRHRRQSEGRVTDLQIKELKMPRGIA 1769
Query: 4842 VDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGAS 4663
VDW+ N+Y+TD D I V M G+ + L+ G +++P AIV++P + ++W DWG
Sbjct: 1770 VDWVAGNLYWTDSGRDVIEVAQMSGQNCKTLISGM-IDEPYAIVVNPQRGTMYWADWGNH 1828
Query: 4662 AHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMV 4483
I MDG+ Q ++ + I+WP LAVD +RLY+ DA I S DGS +
Sbjct: 1829 PKIETAAMDGTLRQTLVHE-NIQWPTGLAVDYFNERLYWADAKLSVIGSVRLDGSDPVIS 1887
Query: 4482 ---LRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVH 4312
L+ ++ H F++ +FEDY+Y + N+ + RV+K + L I H
Sbjct: 1888 VSGLKNNLLHPFSIDIFEDYIYGVTYINNIVFRVNKFGKGKMENLTTG---------INH 1938
Query: 4311 PS---LQSMGSLKTARHPCSQPARCDNLCIPANTPDLTTSSDNFTCMCAQGFRSEGRSCV 4141
S L +PC + +C+ LC+ S C C + ++ +CV
Sbjct: 1939 ASDIVLHHRYKQPEMTNPCDR-KKCEWLCL--------LSPSGPVCTCPNKYVADNGTCV 1989
Query: 4140 SECKP 4126
+ P
Sbjct: 1990 EKPVP 1994
Score = 303 bits (776), Expect = 4e-80
Identities = 394/1594 (24%), Positives = 567/1594 (34%), Gaps = 206/1594 (12%)
Frame = -1
Query: 4725 PRAIVLDPLQALVFWTDWGASA-HIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLY 4549
PRA VLD Q L+FWT+W A I R +++G+N VI+ I+ PN LA+D A++LY
Sbjct: 84 PRAFVLDECQDLMFWTNWNEQAPSIMRASLNGANVLVIIGS-DIKTPNGLAIDHRAEKLY 142
Query: 4548 FGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTN 4369
F DA D I C YDGS R ++L+ H F LAV+ DY++W+DW + R +
Sbjct: 143 FSDATLDKIERCEYDGSSRYVLLKNEPVHPFGLAVYGDYIFWTDWVRRAVLRADNSQWAS 202
Query: 4368 RKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPC-SQPARCDNLCIPANTPDLTTSSDN 4192
SL + + PC + C +LC+P TS
Sbjct: 203 --------------------SLWANDTNNCEFSPCRTNNGGCQDLCLP-------TSDGR 235
Query: 4191 FTCMCAQGFRSEGRSCVSECKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVC 4012
C C +G R + C P + C V+G
Sbjct: 236 VNCSC-RGDRHLLED--NTCSPLNMSCGS--------------------------VDG-- 264
Query: 4011 PPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCG 3832
F CG C+ S CDG+ C DE+ ++C N C + +C
Sbjct: 265 ---------FECGN------GDCINYSLTCDGMAHCKDKSDEKQSYCANRICKKGYRRC- 308
Query: 3831 DKKKCIPLTSVCDKEKDCDDGSDELNCE--------------------ITSCKPDFFACF 3712
+CI CD DC D SDEL C +T CKP F C
Sbjct: 309 INGRCIGHQFWCDGTDDCGDHSDELPCNTLLVLISQGLLPNWFAFLLLVTLCKPGEFQCK 368
Query: 3711 NGTAISK---------------------------------------------CIPKEFYC 3667
+G+ IS C + C
Sbjct: 369 DGSCISNFSRCDQVVNCEDASDEMNCQSTDCSRFFRLGVKGASFQSCERTTLCYLSSWVC 428
Query: 3666 DGEDDCPEGQDE---PDSCFGIGECTHEQFQCTSGKCIPKRRQCDGTLDCRDGSDEKGCK 3496
DG +DC + DE PD +C F C SG+CIP CD DC +G+DE C
Sbjct: 429 DGNNDCGDFSDEKNCPDK--RKLKCPVNFFACPSGRCIPMSWTCDKENDCENGADETHCD 486
Query: 3495 KECAIV----CDNSCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKENRKCGG------ 3346
K C ++ C+ + +CDG C DGSDED++ C K E +C G
Sbjct: 487 KFCTSTQFECANHRCISSHWVCDGSDDCGDGSDEDQK-CKSK-TCSPEAFQCPGSHMCVP 544
Query: 3345 --FACDGIVDCEDGSDEK---GC--------PDLECHLASN----KSLICDGTIDCSSGK 3217
+ CDG DC DG+DE GC P+ E + K +CD +DCS G
Sbjct: 545 QRWKCDGDKDCPDGADESVKAGCMYTNSTCDPENEFMCQNRQCIPKHFVCDLDVDCSDGS 604
Query: 3216 DEN-NC-HNNGESNFFQCS---MQTIKEWQVCDGRWDCADGLDESPE--MCASRKARCFR 3058
DE+ C + + F+C+ K+W+ CDG +DC D DE+P+ C S + C
Sbjct: 605 DESPECEYPTCGPDEFRCANGRCLNQKKWE-CDGEFDCHDHSDEAPKNPRCTSSERTCND 663
Query: 3057 IGYCDDKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKGKYRCTNGRCIDV----SAR 2890
+ CL+ T LCD DC DGSDE + K + C D+ R
Sbjct: 664 SAFTCLNGNCLN-ETLLCDRNDDCGDGSDELNCFINECLNSKLSGCSQLCDDLKIGYKCR 722
Query: 2889 XXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLS 2710
EC C+Q+C + + + C C G+
Sbjct: 723 CHPGFQLKRDGKTCVDVDECLTTYPCSQRC-INTHGSFHCLCVDGF-------------Q 768
Query: 2709 KSAEMFITNGNRLHL--MSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGI 2536
E ++ NR +L ++L+ S ++++ V + + G + G+
Sbjct: 769 PKEEPYLIFANRYYLRKLNLDGSNYTLIKQVRSAPAETMRWSSLLGPCARFNPFRHFQGL 828
Query: 2535 GNS-RVDIRSKKWSDGLIGSWGEEESTAGLITYDFMHNN---VYFTESSEQNRGVLFD-R 2371
N+ +D +++ +I W + + +I M+ + V S G+ D
Sbjct: 829 NNAVALDFH---YAEQMI-YWTDVTTQGSMIRRMHMNGSNMEVLHRTSLSNPDGLAVDWV 884
Query: 2370 QANIY-VAKAKDT--------STRTLIVNS-TGTINSLAVDPIKRLIFWTTSAPVPRILS 2221
N+Y K +DT + RT++VNS +LAVD R ++W+ P I
Sbjct: 885 GGNLYWCDKGRDTIEVSKLNGAYRTVLVNSGLREPRALAVDVRYRYLYWSDWGDNPHIGR 944
Query: 2220 ANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGR 2041
+DG +VE I P + LDF N+R+YW D + IE S DG
Sbjct: 945 IGMDG-----------SNRSVIVEEKITWPNGLTLDFINDRIYWADAREDYIEFASLDGT 993
Query: 2040 DRRTVRKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGKTNKYVQKIREVSPRIQI 1864
+R TV ++ M + YIY SI+R HK G TNK I + + +
Sbjct: 994 NRHTVLNHDIPHI-FAMTLFEEYIYWTDWETKSINRAHKTQG-TNK-TTLISTLHRPMDV 1050
Query: 1863 RVAHPAK--HTVSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIP----KCLCGPGRFFE 1702
+ HP + ++H PCQ++ + +C +L P KC C P F+
Sbjct: 1051 HIYHPYRQPEVLNH------PCQTNNGGCSNLC--------LLSPGGGYKCAC-PTNFYL 1095
Query: 1701 VSTK-----------------KCMQLREKDQEASQCGDYFCYNNAGCSPQKTCVCPPGFY 1573
S + KC+ K CGD A C K C PG +
Sbjct: 1096 ASDQRTCMSNCTASQFVCKNDKCIPFWWKCDTEDDCGDR-SDEPADCPEFK---CRPGQF 1151
Query: 1572 GRQCEINECSE---TCWNGETCAVQEFGSTTNVVCHCPSNYT---QSSCATNV--CEGV- 1420
QC C+ C C + ++ PS + S C + C G
Sbjct: 1152 --QCGTGICTNPAYICDGDNDCQDNSDEANCDIHVCLPSQFKCSHPSRCIPGIFRCNGQD 1209
Query: 1419 -CG---PRGSCKTVPCPKDEPHCRSYSFC-----------ECDKGWTGPHCRHKADAKVC 1285
CG C V C + C C +C G P + V
Sbjct: 1210 NCGDGEDEKDCPEVTCAPTQFQCAITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVD 1269
Query: 1284 YGHCFSGGACDGEGPLNLRC----SCGDG-------LTGNRCQ----NCVGHECLNGGF- 1153
C G C P +C CGD C+ C + C+ G +
Sbjct: 1270 EFRCKDSGRCI---PARWKCDGEDDCGDASDEPKEECAERTCEPYQFRCKNNRCVPGRWQ 1326
Query: 1152 CSYANSNRSLPHCICPSGFTGDHCEEYLCKD---ACPFGS------KCTYDITKPMDPIT 1000
C Y N C D C C + AC G KC D
Sbjct: 1327 CDYDND--------CGDNSDEDKCMPRQCSESEFACTNGRCIAGRWKCDGD--------- 1369
Query: 999 CSCEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDD 820
C + H D C C+NG C+P RCD C D
Sbjct: 1370 HDCADGSDEHGCDLK--CDTDHFQCNNG-------------HCIP--IRWRCDADPDCLD 1412
Query: 819 YCTNNSKCTITNGTH-----FECD---CKPGFKGLRCEQETKCSECSNEAKCIKKPSGTV 664
++ C H F+C+ CKP +C+ E C + S+E
Sbjct: 1413 -GSDEENCGSATERHCPADEFQCNNTLCKP--LAWKCDGEDDCGDNSDE----------- 1458
Query: 663 ICQCPQGLGGEYCEKITATSCHQLECKNGGYCLK 562
E C K C+N CL+
Sbjct: 1459 --------NPEQCRKFQCPPTRAFRCQNDRVCLQ 1484
Score = 154 bits (388), Expect = 4e-35
Identities = 186/735 (25%), Positives = 269/735 (36%), Gaps = 77/735 (10%)
Frame = -1
Query: 4980 DVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRN 4801
D DL++WT+ S+ N N +I S K +G+A+D +Y++D
Sbjct: 90 DECQDLMFWTNWNEQAPSIMRASL-NGANVLVIIGS-DIKTPNGLAIDHRAEKLYFSDAT 147
Query: 4800 HDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHI----------- 4654
D I C+ G +LLK P++ V +FWTDW A +
Sbjct: 148 LDKIERCEYDGSSRYVLLKNEPVHPFGLAVYGD---YIFWTDWVRRAVLRADNSQWASSL 204
Query: 4653 -----------------------------GRMNMDGSNEQVILQDRTIRWPNALAVDAPA 4561
GR+N ++ +L+D T N
Sbjct: 205 WANDTNNCEFSPCRTNNGGCQDLCLPTSDGRVNCSCRGDRHLLEDNTCSPLNMSCGSVDG 264
Query: 4560 QRLYFGDAHR-----DYIASCNYDGSKR------RMVLRGSVRHIFALAVFEDYVYWSDW 4414
GD D +A C ++ R+ +G R I + + +W D
Sbjct: 265 FECGNGDCINYSLTCDGMAHCKDKSDEKQSYCANRICKKGYRRCINGRCI--GHQFWCDG 322
Query: 4413 HNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPC-SQPARCDNL 4237
+ + ++ VLI ++ +L G + C S +RCD +
Sbjct: 323 TDDCGDHSDELPCNTLLVLISQGLLPNWFAFLLLVTLCKPGEFQCKDGSCISNFSRCDQV 382
Query: 4236 CIPANTPDLTTSSDNFTCM---CAQGFR--SEGRSCVSECKPNDFVCTKTYKCISSWWRX 4072
N D +SD C C++ FR +G S S C +T C S W
Sbjct: 383 ---VNCED---ASDEMNCQSTDCSRFFRLGVKGASFQS--------CERTTLCYLSSW-- 426
Query: 4071 XXXXXXXXXXXXGYFVEGVCP---PFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCS 3901
+ E CP C F C + +C+ S CD DC
Sbjct: 427 ---VCDGNNDCGDFSDEKNCPDKRKLKCPVNFFAC------PSGRCIPMSWTCDKENDCE 477
Query: 3900 GGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDE-LNCEITSCKPDF 3724
G DE C+ F CT QF+C + +CI VCD DC DGSDE C+ +C P+
Sbjct: 478 NGADE--THCDKF-CTSTQFECAN-HRCISSHWVCDGSDDCGDGSDEDQKCKSKTCSPEA 533
Query: 3723 FACFNGTAISKCIPKEFYCDGEDDCPEGQDE---PDSCFGIGECTHE-QFQCTSGKCIPK 3556
F C C+P+ + CDG+ DCP+G DE + C E +F C + +CIPK
Sbjct: 534 FQC---PGSHMCVPQRWKCDGDKDCPDGADESVKAGCMYTNSTCDPENEFMCQNRQCIPK 590
Query: 3555 RRQCDGTLDCRDGSDEK-GCKKECAIVCDNSCVHADDL------CDGKKKCNDGSDEDEE 3397
CD +DC DGSDE C+ + C + L CDG+ C+D SDE +
Sbjct: 591 HFVCDLDVDCSDGSDESPECEYPTCGPDEFRCANGRCLNQKKWECDGEFDCHDHSDEAPK 650
Query: 3396 ACVIKQLLEKENRKCGGFACDGIVDCEDGSDEKGCPDLECHLASNKSLICDGTIDCSSGK 3217
R C D C +G+ N++L+CD DC G
Sbjct: 651 ----NPRCTSSERTCN----DSAFTCLNGN------------CLNETLLCDRNDDCGDGS 690
Query: 3216 DENNCHNNG--ESNFFQCSMQTIKEWQVCDGRWDCADGLDESPEMCASRKARC---FRIG 3052
DE NC N S CS Q+CD ++ K RC F++
Sbjct: 691 DELNCFINECLNSKLSGCS-------QLCD-------------DLKIGYKCRCHPGFQLK 730
Query: 3051 YCDDKKQCLDVSTAL 3007
D K C+DV L
Sbjct: 731 --RDGKTCVDVDECL 743
Score = 137 bits (346), Expect = 3e-30
Identities = 113/365 (30%), Positives = 149/365 (39%), Gaps = 15/365 (4%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC--TCNENEFRCQS 6400
D+ D C R C F C NG CI + C+ +DCA+ +DE C C+ + F+C +
Sbjct: 1335 DNSDEDKCMPRQCSESEFACTNGRCIAGRWKCDGDHDCADGSDEHGCDLKCDTDHFQCNN 1394
Query: 6399 GACIPSKARCNHMQDCNDASDEIGC---PFRNCSALNEFGMTGLINCATTSQCIHPSWKC 6229
G CIP + RC+ DC D SDE C R+C A +EF C T C +WKC
Sbjct: 1395 GHCIPIRWRCDADPDCLDGSDEENCGSATERHCPA-DEF------QCNNT-LCKPLAWKC 1446
Query: 6228 DGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCA 6049
DG +DC D SDE C F C R C+ +CDG +C
Sbjct: 1447 DGEDDCGDNSDENP----------EQCRKFQCPPTRAFRCQNDRVCLQVSKRCDGVNNCG 1496
Query: 6048 DGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNAT 5869
D SDE NC T + SC S + C L+ K R C + C+
Sbjct: 1497 DNSDELNCR----TCWTPSC-SYEICAFLDCK---RNICCASTETPPAVPTCEKD----E 1544
Query: 5868 FRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACELT 5689
F C NHRCI RC+ +DC D GSDE+ C +T + C
Sbjct: 1545 FLCANHRCISSTLRCNLFNDCED----FGSDEIGCKT-------------DTKLNDCRSN 1587
Query: 5688 AVLCDGIQDCSDGFDEKNCASLDR----QCKP------NEWMCDSGQCIDSGRLCDASVD 5539
C DG DE +C + CKP + D +C+ G +C S +
Sbjct: 1588 RT------HCGDG-DEAHCVTNGTDSFCSCKPGFQKIGHRTCGDKNECLQFG-VCSHSCN 1639
Query: 5538 CVDGS 5524
GS
Sbjct: 1640 NTKGS 1644
Score = 100 bits (248), Expect = 6e-19
Identities = 103/416 (24%), Positives = 146/416 (34%), Gaps = 33/416 (7%)
Frame = -1
Query: 1173 ECLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCS 994
+CLNGG C + N+ R + C C + G+ CE C+D
Sbjct: 2009 QCLNGGSC-FLNA-RQVAKCRCQPSYIGERCEINQCRD---------------------- 2044
Query: 993 CEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYC 814
+C NGG C + C+C F GP C C DYC
Sbjct: 2045 ---------------------YCKNGGTCTASHAGVPTCRCPKGFTGPTCSRQT-CQDYC 2082
Query: 813 TNNSKCTITNGTHFECDCKPGFKGLRCEQETKCSECSNEAKCIKKPSGTVICQCPQGLGG 634
N C+++ G C C ++G RC+ T C N C++ +GT +C C G
Sbjct: 2083 QNGGSCSVSMGNQPTCSCPSEYQGDRCQYTTCEGFCHNSGTCLQTSNGTKLCLCSNQYVG 2142
Query: 633 EYCEKITATSCHQLECKNGGYCLKPDPSANRT------SPTC------LCSPGFKGLLCS 490
CE C +C PS+ T PT LCS CS
Sbjct: 2143 HQCELDKCQFCGTGKCFT-------SPSSEVTCRYVLGMPTVLPWTAFLCSLFISNTACS 2195
Query: 489 SN---------ACENFCLHDGNCTLD-EYFEPQCECYQAFIGDRCQYRIHQHAVIFSDDD 340
C N+C G C++D PQC+C + G C+ S
Sbjct: 2196 CPNGQIQPSCFTCLNYCSR-GQCSVDSRTLLPQCKCPAGWSGYTCEIAAAPVDSSASGGS 2254
Query: 339 SGWIKSFXXXXXXXXXXXXXXXIFANRSNRFAVFRQFRHNPLQNQGAPVDQFSNPAYLID 160
+ I ++ R R A + F+H+ + N GA + NPAY I
Sbjct: 2255 TASIVVPVLLLLLLALLAVGAVLWYRRRMRGA--KGFQHHRMTN-GAMNVEIGNPAYKIY 2311
Query: 159 EG-----GIELVTQNTSLVSSHDRGSFNNPVFEQEMVPIYN------DTVENHELL 25
EG EL+ + +L +F NPV+ + +N T E ELL
Sbjct: 2312 EGDPDDDAGELLDSDFAL-DPDKPTNFTNPVYATLYMGAHNSRNSLASTDEKKELL 2366
Score = 89.4 bits (220), Expect = 1e-15
Identities = 81/297 (27%), Positives = 107/297 (35%), Gaps = 39/297 (13%)
Frame = -1
Query: 6042 SDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSK-----GG 5878
+D NC+ C + C+ C+P DGR +C D H E S G
Sbjct: 207 NDTNNCEFSPCRTNNGGCQDL--CLPTS---DGRVNCSCRGDRHLLEDNTCSPLNMSCGS 261
Query: 5877 NATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVAC 5698
F C N CI + CDG C D + ++ A R RC + C+
Sbjct: 262 VDGFECGNGDCINYSLTCDGMAHCKDKS----DEKQSYCANRICKKGYRRCINGRCIG-- 315
Query: 5697 ELTAVLCDGIQDCSDGFDEKNCAS------------------LDRQCKPNEWMCDSGQCI 5572
CDG DC D DE C + L CKP E+ C G CI
Sbjct: 316 --HQFWCDGTDDCGDHSDELPCNTLLVLISQGLLPNWFAFLLLVTLCKPGEFQCKDGSCI 373
Query: 5571 DSGRLCDASVDCVDGSDEWVEICSLSEPPR--RGCPSGWSCLLTNGTIGCLQEQQLCDGR 5398
+ CD V+C D SDE C ++ R R G S T C +CDG
Sbjct: 374 SNFSRCDQVVNCEDASDEM--NCQSTDCSRFFRLGVKGASFQSCERTTLCYLSSWVCDGN 431
Query: 5397 RDCMSGIDEQ-CDN-------------PQGNCSSTRNSCDQTWNCQRHAGFESCSCD 5269
DC DE+ C + P G C +CD+ +C+ G + CD
Sbjct: 432 NDCGDFSDEKNCPDKRKLKCPVNFFACPSGRCIPMSWTCDKENDCEN--GADETHCD 486
Score = 82.4 bits (202), Expect = 1e-13
Identities = 52/173 (30%), Positives = 74/173 (42%), Gaps = 5/173 (2%)
Frame = -1
Query: 882 KCK--CLPRFAGPRCDVPVQCDDYCTNNSKCT---ITNGTHFECDCKPGFKGLRCEQETK 718
KC+ CL +GP C P + Y +N C + + F +P C+
Sbjct: 1961 KCEWLCLLSPSGPVCTCP---NKYVADNGTCVEKPVPTQSPFSPPSEP------CD---- 2007
Query: 717 CSECSNEAKCIKKPSGTVICQCPQGLGGEYCEKITATSCHQLECKNGGYCLKPDPSANRT 538
+C N C C+C GE CE C CKNGG C +++
Sbjct: 2008 -IQCLNGGSCFLNARQVAKCRCQPSYIGERCE---INQCRDY-CKNGGTCT----ASHAG 2058
Query: 537 SPTCLCSPGFKGLLCSSNACENFCLHDGNCTLDEYFEPQCECYQAFIGDRCQY 379
PTC C GF G CS C+++C + G+C++ +P C C + GDRCQY
Sbjct: 2059 VPTCRCPKGFTGPTCSRQTCQDYCQNGGSCSVSMGNQPTCSCPSEYQGDRCQY 2111
Score = 70.5 bits (171), Expect = 5e-10
Identities = 46/137 (33%), Positives = 65/137 (46%), Gaps = 5/137 (3%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADES-NC---TCNENEFRC 6406
D E+ C R C P +F VC+ DC++ +DES C TC +EFRC
Sbjct: 575 DPENEFMCQNRQCIPKHF------------VCDLDVDCSDGSDESPECEYPTCGPDEFRC 622
Query: 6405 QSGACIPSKA-RCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKC 6229
+G C+ K C+ DC+D SDE R C++ C C++ + C
Sbjct: 623 ANGRCLNQKKWECDGEFDCHDHSDEAPKNPR-CTSSERTCNDSAFTC-LNGNCLNETLLC 680
Query: 6228 DGTNDCYDGSDEKDCFV 6178
D +DC DGSDE +CF+
Sbjct: 681 DRNDDCGDGSDELNCFI 697
Score = 59.7 bits (143), Expect = 9e-07
Identities = 97/434 (22%), Positives = 151/434 (34%), Gaps = 54/434 (12%)
Frame = -1
Query: 1791 CPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGC 1612
C + CV D+ + CG F + +C+ R K CGD C
Sbjct: 1245 CDRDNDCVDGSDEPANCT-QMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDASDEPKEEC 1303
Query: 1611 SPQKTCV----------CPPGF----YGRQCEINECSETCWNGETCAVQEFGSTTNVVC- 1477
+ ++TC C PG Y C N + C + C+ EF + TN C
Sbjct: 1304 A-ERTCEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDEDKCMPRQ-CSESEF-ACTNGRCI 1360
Query: 1476 ----HCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSYSF-CECDKGWTGPHC 1312
C ++ CA E C + C T + HC + C+ D P C
Sbjct: 1361 AGRWKCDGDH---DCADGSDEHGCDLK--CDTDHFQCNNGHCIPIRWRCDAD-----PDC 1410
Query: 1311 RHKADAKVCYG----HCFSGG-ACDGE--GPLNLRCS----CGDGLTGN-------RCQN 1186
+D + C HC + C+ PL +C CGD N +C
Sbjct: 1411 LDGSDEENCGSATERHCPADEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEQCRKFQCPP 1470
Query: 1185 CVGHECLNGGFCSYANSN-RSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMD 1009
C N C + + +C GD+ +E C+ + C+Y+I +D
Sbjct: 1471 TRAFRCQNDRVCLQVSKRCDGVNNC-------GDNSDELNCRTC--WTPSCSYEICAFLD 1521
Query: 1008 PITCSCEQNAAAHNTDCSPI---CQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPR--C 844
C++N +T+ P C+K C N RC+ + F C
Sbjct: 1522 -----CKRNICCASTETPPAVPTCEKDEFLCANH-RCISSTLRCNLFNDCEDFGSDEIGC 1575
Query: 843 DVPVQCDDYCTNNSKC-------TITNGTHFECDCKPGFKGL---RCEQETKCSECSNEA 694
+ +D +N + C +TNGT C CKPGF+ + C + +C + +
Sbjct: 1576 KTDTKLNDCRSNRTHCGDGDEAHCVTNGTDSFCSCKPGFQKIGHRTCGDKNECLQFGVCS 1635
Query: 693 KCIKKPSGTVICQC 652
G+ C C
Sbjct: 1636 HSCNNTKGSYKCSC 1649
Score = 58.2 bits (139), Expect = 3e-06
Identities = 155/741 (20%), Positives = 245/741 (32%), Gaps = 97/741 (13%)
Frame = -1
Query: 2331 TRTLIVNSTGTINSLA--------VDPIKRLIFWTT-SAPVPRILSANLDGKPIAQPFKT 2179
+RT+ N +N A +D + L+FWT + P I+ A+L+G +
Sbjct: 65 SRTVAYNRDTVVNMSAEDHPRAFVLDECQDLMFWTNWNEQAPSIMRASLNGANVL----- 119
Query: 2178 GSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTP 1999
++ +I P + +D E+LY+ D IE +DG R + K E P
Sbjct: 120 ------VIIGSDIKTPNGLAIDHRAEKLYFSDATLDKIERCEYDGSSRYVLLKNE-PVHP 172
Query: 1998 VTMDVLGGYIYLITRQGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITH 1819
+ V G YI+ + +R R A ++ S +
Sbjct: 173 FGLAVYGDYIF--------------------WTDWVRRAVLR-----ADNSQWASSLWAN 207
Query: 1818 QKNPCQSDYCPSNT-----VCVPDQDKNGILIPKCLC-GPGRFFEVSTKKCMQLREKDQE 1657
N C+ C +N +C+P D C C G E +T + + +
Sbjct: 208 DTNNCEFSPCRTNNGGCQDLCLPTSDGR----VNCSCRGDRHLLEDNTCSPLNMSCGSVD 263
Query: 1656 ASQCGDYFCYN-NAGCSPQKTCVCPPGFYGRQCEINECSE---TCWNGETCAVQEFGSTT 1489
+CG+ C N + C C C C + C NG Q + T
Sbjct: 264 GFECGNGDCINYSLTCDGMAHCKDKSDEKQSYCANRICKKGYRRCINGRCIGHQFWCDGT 323
Query: 1488 NVVCHCPSNYTQSSCAT---NVCEG-------------VCGP------RGSC-------- 1399
+ C + + C T + +G +C P GSC
Sbjct: 324 D---DCGDHSDELPCNTLLVLISQGLLPNWFAFLLLVTLCKPGEFQCKDGSCISNFSRCD 380
Query: 1398 KTVPC--PKDEPHCRSYSFCECDK----GWTGPHCRHKADAKVCYGHCFSGGACDGEGPL 1237
+ V C DE +C+S +C + G G + +CY S CDG
Sbjct: 381 QVVNCEDASDEMNCQS---TDCSRFFRLGVKGASFQSCERTTLCY---LSSWVCDGNN-- 432
Query: 1236 NLRCSCGDGLTGNRCQNCVGHECLNGGFCSYANSNRSLP-------HCICPSGFTGDHCE 1078
CGD C + +C F S R +P C +G HC+
Sbjct: 433 ----DCGDFSDEKNCPDKRKLKCPVNFFA--CPSGRCIPMSWTCDKENDCENGADETHCD 486
Query: 1077 EYLCKDACPFGS-KC--TYDITKPMDPITCSCEQNAAAHNTDCSPICQKQPNWCHNGGRC 907
++ + +C ++ + D +++ + CSP +C
Sbjct: 487 KFCTSTQFECANHRCISSHWVCDGSDDCGDGSDEDQKCKSKTCSP----------EAFQC 536
Query: 906 LDTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSK--CTITNGT-----HFEC---DCK 757
PG C+P+ +CD C D + K C TN T F C C
Sbjct: 537 ------PGSHMCVPQ--RWKCDGDKDCPDGADESVKAGCMYTNSTCDPENEFMCQNRQCI 588
Query: 756 PGFKGLRCEQETKCSECSNEA-KCIKKPSGTVICQCPQG--LGGEYCEKITATSCHQL-- 592
P K C+ + CS+ S+E+ +C G +C G L + E CH
Sbjct: 589 P--KHFVCDLDVDCSDGSDESPECEYPTCGPDEFRCANGRCLNQKKWECDGEFDCHDHSD 646
Query: 591 ECKNGGYCLKPDPSANRTSPTCL----------------CSPGFKGLLCSSNACENFCLH 460
E C + + N ++ TCL C G L C N C N L
Sbjct: 647 EAPKNPRCTSSERTCNDSAFTCLNGNCLNETLLCDRNDDCGDGSDELNCFINECLNSKLS 706
Query: 459 DGNCTLDEY-FEPQCECYQAF 400
+ D+ +C C+ F
Sbjct: 707 GCSQLCDDLKIGYKCRCHPGF 727
>gi|13562118|ref|NP_110454.1| low density lipoprotein receptor-related
protein 2; glycoprotein 330; low density
lipoprotein-related protein 2; megalin [Rattus
norvegicus]
gi|1708867|sp|P98158|LRP2_RAT Low-density lipoprotein
receptor-related protein 2 precursor (Megalin)
(Glycoprotein 330) (gp330)
gi|11275227|pir||T42737 gp330 protein precursor - rat
gi|561853|gb|AAA51369.1| megalin
Length = 4660
Score = 743 bits (1919), Expect = 0.0
Identities = 559/1821 (30%), Positives = 805/1821 (43%), Gaps = 149/1821 (8%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC---TCNEN-EFRCQ 6403
DE C+ CR F CGNG C+P C+ NDC + +DE+ C CN EF C
Sbjct: 2731 DELPTVCAFHTCRSTAFTCGNGRCVPYHYRCDYYNDCGDNSDEAGCLFRNCNSTTEFTCS 2790
Query: 6402 SGACIPSKARCNHMQDC--NDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKC 6229
+G CIP CN + +C ND SDE CP C C TT+ C+ ++ C
Sbjct: 2791 NGRCIPLSYVCNGINNCHDNDTSDEKNCPPHTCPP-------DFTKCQTTNICVPRAFLC 2843
Query: 6228 DGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCA 6049
DG NDC DGSDE + A +C + +F CL+ + C+P +W CDG+ DCA
Sbjct: 2844 DGDNDCGDGSDENPIYC----------ASHTCRSN-EFQCLSPQRCIPSYWFCDGEADCA 2892
Query: 6048 DGSDEKNC---DAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDE---HQCETE-CD 5890
DGSDE + C + +F C++ + CI CDG DC D DE H CE + C
Sbjct: 2893 DGSDEPDTCGHSVNTCRASQFQCDNGR-CISGNWVCDGDNDCGDMSDEDQRHHCELQNCS 2951
Query: 5889 SKGGNATFRCTN-----HRCIPMAWRCDGTDDCMDNAKSLGSDEV-DCAAGRTSFHVPSR 5728
S F C N RCIP W CDG DC D L + + C+AG S
Sbjct: 2952 S----TQFTCVNSRPPNRRCIPQYWVCDGDADCSDALDELQNCTMRTCSAGEFS------ 3001
Query: 5727 CADETCVVACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDA 5548
CA+ CV + CD DC D DE+ C+ C N++ C +G+CI +CD
Sbjct: 3002 CANGRCV----RQSFRCDRRNDCGDYSDERGCSY--PPCHANQFTCQNGRCIPRFFVCDE 3055
Query: 5547 SVDCVDGSDEWVEICSLSEPPRRGCP-SGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDE 5371
DC DGSDE +C EP CP + C NG C++ ++C+ DC DE
Sbjct: 3056 DNDCGDGSDEQEHLCHTPEPT---CPLHQFRC--DNGH--CIEMGRVCNHVDDCSDNSDE 3108
Query: 5370 QCDNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKAN--C 5197
+ S+ + CD NC CSC GY L DK++C+ C ++ C
Sbjct: 3109 KGCGINECLDSSISRCDH--NCTDTITSFYCSCLPGYKLMS-DKRSCVDIDECKESPQLC 3165
Query: 5196 SHFCIDRRDVG-HQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKAT 5020
S C VG + C CAPGYI + K CR+N IE ++ + ++ T DG + +
Sbjct: 3166 SQKC--ENVVGSYICKCAPGYIREPDGKSCRQNSNIEPYLIFSNRYYIRNLTTDGSSYSL 3223
Query: 5019 LLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMS-NQPNTYRVINSLPTKGIDGIA 4843
+L L N VALD+D +YW D K I M N+ N +IN + + +A
Sbjct: 3224 ILQGLGNVVALDFDRVEKRLYWIDA----EKQIIERMFLNKTNRETIINHRLRRA-ESLA 3278
Query: 4842 VDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTP-------LNDPRAIVLDPLQALVF 4684
VDW+ R +Y+ D D + V D+ GR +++ + PR IVL P + V+
Sbjct: 3279 VDWVSRKLYWLDAILDCLFVSDLEGRHRKMIAQHCVDANNTFCFEHPRGIVLHPQRGHVY 3338
Query: 4683 WTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYD 4504
W DWG A+IGR+ MDG+N+ VI+ + I WPNA+ +D LY+ DAH YI + +
Sbjct: 3339 WADWGVHAYIGRIGMDGTNKSVIISTK-IEWPNAITIDYTNDLLYWADAHLGYIEFSDLE 3397
Query: 4503 GSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGF 4324
G R V GS+ H FAL +FED V+W+DW+ T+E+ +K G+ R VL+ + ++P
Sbjct: 3398 GHHRHTVYDGSLPHPFALTIFEDTVFWTDWNTRTVEKGNKYDGSGRVVLV-NTTHKPFDI 3456
Query: 4323 KIVHPSLQSMGSLKTARHPC-SQPARCDNLCIPANTPDLTTSSDNFTCMCAQGFRS---- 4159
+ HP Q + S +PC + C +LC+ + FTC C F++
Sbjct: 3457 HVYHPYRQPIMS-----NPCGTNNGGCSHLCL------IKAGGRGFTCACPDDFQTVQLR 3505
Query: 4158 EGRSCVSECKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFV 3979
+ C+ C F+C KCI WW+ +CP C GQF
Sbjct: 3506 DRTLCMPMCSSTQFLCGNNEKCIPIWWKCDGQKDCSDGSDE----PDLCPHRFCRLGQFQ 3561
Query: 3978 CGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSV 3799
C C LC+ +DC+ G DE+ CE+ C +++C +K+ CIP +
Sbjct: 3562 C------RDGNCTSPQALCNARQDCADGSDEDRVLCEHHRCESNEWQCANKR-CIPQSWQ 3614
Query: 3798 CDKEKDCDDGSDE--LNCEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPD 3625
CD DC D SDE +C +C+P F C NG +CIP+ + CD ++DC + DEP
Sbjct: 3615 CDSVNDCLDNSDEDTSHCASRTCRPGQFKCNNG----RCIPQSWKCDVDNDCGDYSDEP- 3669
Query: 3624 SCFGIGECT--------HEQFQC-TSGKCIPKRRQCDGTLDCRDGSDEKGCKK------- 3493
I ECT H +F C T+ +CIP+ C+G DCRD SDE+GC+
Sbjct: 3670 ----IDECTTAAYNCDNHTEFSCKTNYRCIPQWAVCNGFDDCRDNSDEQGCESVPCHPSG 3725
Query: 3492 --ECAIVCDNSCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKENR----KC--GGFAC 3337
CA ++ C+ CDG C D SDE E CV ++ E E R +C + C
Sbjct: 3726 DFRCA---NHHCIPLRWKCDGTDDCGDNSDE--ENCVPRECSESEFRCADQQCIPSRWVC 3780
Query: 3336 DGIVDCEDGSDEKGCPDLECHLAS---------NKSLICDGTIDCSSGKDENNCHN---N 3193
D DC D SDE+ C CH K+L CDG DC DE+ C N
Sbjct: 3781 DQENDCGDNSDERDCEMKTCHPEHFQCTSGHCVPKALACDGRADCLDASDESACPTRFPN 3840
Query: 3192 GE---SNFFQCSMQT-IKEWQVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCL 3025
G + F+C I+ + +CDG DC DG DE +C + + CD+ + C+
Sbjct: 3841 GTYCPAAMFECKNHVCIQSFWICDGENDCVDGSDEEIHLCFNIPCESPQRFRCDNSR-CV 3899
Query: 3024 DVSTALCDGIRDCFDGSDENPIHC-----KDMCKGKYRCTNGRCI-------DVSARXXX 2881
LC+G+ DC DGSDE HC K +Y+C+NG CI +V+
Sbjct: 3900 -YGHQLCNGVDDCGDGSDEKEEHCRKPTHKPCTDTEYKCSNGNCISQHYVCDNVNDCGDL 3958
Query: 2880 XXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSA 2701
AE +C Q C + C C PG+ + +D+N C+ +++
Sbjct: 3959 SDETGCNLGDNRTCAE----NICEQNCTQLSSGGFICSCRPGFKPSTSDKNSCQDINECE 4014
Query: 2700 EMFITNGNRLHLMSLENSQVSV-LRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSR 2524
E I S NS+ S V K G D L+ + +
Sbjct: 4015 EFGICP------QSCRNSKGSYECFCVDGFKSMSTHYGERCAADGSPPLLLLPENVRIRK 4068
Query: 2523 VDIRSKKWSDGLIGSWGEEESTAGLITYDFMHNN-----VYFT----------------- 2410
+ S+K+S+ L EEE I YD+ + VY+T
Sbjct: 4069 YNTSSEKFSEYL-----EEEEHIQTIDYDWDPEHIGLSVVYYTVLAQGSQFGAIKRAYIP 4123
Query: 2409 --ESSEQN---------------RGVLFD-----------RQANIYVAKAKDTSTRTLIV 2314
ES N G+ D + I VA + LI
Sbjct: 4124 NFESGSNNPIREVDLGLKYLMQPDGLAVDWVGRHIYWSDAKSQRIEVATLDGRYRKWLIT 4183
Query: 2313 NSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFE 2134
++AV+P L+FWT P+I SA ++G + LV N+
Sbjct: 4184 TQLDQPAAIAVNPKLGLMFWTDQGKQPKIESAWMNG-----------EHRSVLVSENLGW 4232
Query: 2133 PTSMVLDFSN-ERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT 1957
P + +D+ N +R+YW D + IE + +DG DRR + + P ++D+ +Y +
Sbjct: 4233 PNGLSIDYLNDDRVYWSDSKEDVIEAIKYDGTDRRLIINEAM--KPFSLDIFEDKLYWVA 4290
Query: 1956 RQ-GSIHRMHKFTGKTNKYVQKIREVSPRI-QIRVAHPAKHTVSHITHQKNPCQSDYCPS 1783
++ G + R +KF GK NK +K+ V+P + Q+R+ H ++ S NPC+ C
Sbjct: 4291 KEKGEVWRQNKF-GKENK--EKVLVVNPWLTQVRIFHQLRYNQS----VSNPCK-QVCSH 4342
Query: 1782 NTVCVPDQDKNGILIPKCLCGPGR-FFEVSTKKCMQLREKDQEASQCGDYFCYNNAGC-- 1612
+ P C C G F ST +C E + C + C
Sbjct: 4343 LCLLRPGG-------YSCACPQGSDFVTGSTVQCDAASE--LPVTMPPPCRCMHGGNCYF 4393
Query: 1611 --SPQKTCVCPPGFYGRQCEI 1555
+ C C G+ G CE+
Sbjct: 4394 DENELPKCKCSSGYSGEYCEV 4414
Score = 399 bits (1026), Expect = e-109
Identities = 266/785 (33%), Positives = 374/785 (46%), Gaps = 17/785 (2%)
Frame = -1
Query: 6429 CNENEFRCQSGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQC 6250
C F C +G C+PS RC+ + DC+D SDE C N C QC
Sbjct: 1025 CGSLSFPCNNGKCVPSFFRCDGVDDCHDNSDE-----HQCGVFNNTCSPSAFACVRGGQC 1079
Query: 6249 IHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQC 6070
I W CD NDC DGSDE++C A S T F C C+PK W C
Sbjct: 1080 IPGQWHCDRQNDCLDGSDEQNC---------PTHATSSTCPSTSFTC-DNHVCIPKDWVC 1129
Query: 6069 DGQPDCADGSDEKNCDAK-KCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETEC 5893
D DC+DGSDEKNC A C +F C + CI CDG +DC DG DE C C
Sbjct: 1130 DTDNDCSDGSDEKNCQASGTCQPTQFRCPDHR-CISPLYVCDGDKDCADGSDEAGCVLNC 1188
Query: 5892 DSKGGNATFRCTN-HRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPS--RC- 5725
S A F+C + CI +RCDG DC DN SDE C P +C
Sbjct: 1189 TS----AQFKCADGSSCINSRYRCDGVYDCRDN-----SDEAGCPTRPPGMCHPDEFQCQ 1239
Query: 5724 ADETCVVACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDAS 5545
D TC+ CDG DC G DE + + + C P ++CD+G CI +CD
Sbjct: 1240 GDGTCIP----NTWECDGHPDCIHGSDE-HTGCVPKTCSPTHFLCDNGNCIYKAWICDGD 1294
Query: 5544 VDCVDGSDEWVEICSLSEPPRRGCPSG-WSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQ 5368
DC D SDE + C ++P CPS W C G C+ LCDG DC +G DE
Sbjct: 1295 NDCRDMSDE--KDCP-TQPFH--CPSTQWQC---PGYSTCINLSALCDGVFDCPNGTDES 1346
Query: 5367 CDNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKAN-CSH 5191
Q +CS C T C + +C C GY L+ D KTC C CS
Sbjct: 1347 PLCNQDSCSHFNGGC--THQCMQGPFGATCLCPLGYQLAN-DTKTCEDINECDIPGFCSQ 1403
Query: 5190 FCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLF----TIDGHAKA 5023
C++ R +C C P Y L + + C+ T L+V R K+ T H
Sbjct: 1404 HCVNMRG-SFRCACDPEYTLESDGRTCKV--TGSENPLLVVASRDKIIVDNITAHTHNLY 1460
Query: 5022 TLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIA 4843
+L+ +++ VALD+D + V+W+D+ + S+ RV++ + IA
Sbjct: 1461 SLVQDVSFVVALDFDSVTGRVFWSDLL----QGKTWSVFQNGTDKRVVHDSGLSVTEMIA 1516
Query: 4842 VDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQA--LVFWTDWG 4669
VDW+GRN+Y+TD + I V + G +L+ + PR + LDP ++FW+DWG
Sbjct: 1517 VDWIGRNLYWTDYALETIEVSKIDGSHRTVLISKN-VTKPRGLALDPRMGDNVMFWSDWG 1575
Query: 4668 ASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRR 4489
I R +MDG+ VI+Q++ I WP L++D P + +YF DA+ DYI C+YDG RR
Sbjct: 1576 HHPRIERASMDGTMRTVIVQEK-IYWPCGLSIDYPNRLIYFMDAYLDYIEFCDYDGHNRR 1634
Query: 4488 MVLRGS--VRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIV 4315
V+ + H AL +FED+VYW+D + + +K G N+ V++ ++P+G +
Sbjct: 1635 QVIASDLVLHHPHALTLFEDFVYWTDRGTRQVMQANKWHGGNQSVVMY-SVHQPLGITAI 1693
Query: 4314 HPSLQSMGSLKTARHPCSQPARCDNLCIPANTPDLTTSSDNFTCMCAQGFR--SEGRSCV 4141
HPS Q +R+PC+ A C +LC+ + + +++C C G+ + +CV
Sbjct: 1694 HPSRQ-----PPSRNPCAS-ASCSHLCLLS-----AQAPRHYSCACPSGWNLSDDSVNCV 1742
Query: 4140 SECKP 4126
+P
Sbjct: 1743 RGDQP 1747
Score = 350 bits (898), Expect = 3e-94
Identities = 407/1743 (23%), Positives = 650/1743 (36%), Gaps = 102/1743 (5%)
Frame = -1
Query: 5256 LSPYD--KKTCLRSPSCPKANCSHFCIDRRDVGH-QCFCAPGYILSENQKDCRRNDTIEA 5086
LSP + CL+S CSHFC ++ +C CA G L + K C +
Sbjct: 2337 LSPAELNNNPCLQS----NGGCSHFCFALPELPTPRCGCAFG-TLGNDGKSCATSQ---- 2387
Query: 5085 EILMVYGHRLKLFTI-----DGHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHD--GNK 4927
E ++Y L ++ D ++S +ALDYD +++ +++T + G
Sbjct: 2388 EDFLIYSLNNSLRSLHFDPRDHSLPFQVISVAGTAIALDYDRRNNRIFFTQKLNSLRGQI 2447
Query: 4926 AGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILL 4747
+ ++ S + +++++ DGIA DW+ R IYY+D ++ I G ++
Sbjct: 2448 SYVSLYSGSSSPTVLLSNIGVT--DGIAFDWINRRIYYSDFSNQTINSMAEDGSNRAVIA 2505
Query: 4746 KGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDA 4567
+ ++ PRAIVLDP + ++WTDWG +A I R + G N +V + + ++ WPN LA+D
Sbjct: 2506 R---VSKPRAIVLDPCRGYMYWTDWGTNAKIERATL-GGNFRVPIVNTSLVWPNGLALDL 2561
Query: 4566 PAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVH 4387
LY+ DA I G+ R +V+ + H F L V+ Y+YW+D + I R +
Sbjct: 2562 ETDLLYWADASLQKIERSTLTGTNREVVV-STAFHSFGLTVYGQYIYWTDLYTRKIYRAN 2620
Query: 4386 KITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQP-----ARCDNLCIPAN 4222
K G++ + +P G V +KT R CS P C ++C P
Sbjct: 2621 KYDGSDLVAMTTRLPTQPSGISTV---------VKTQRQQCSNPCDQFNGGCSHICAP-- 2669
Query: 4221 TPDLTTSSDNFTCMCAQG----FRSEGRSCV----SECKPNDFVCTKTYKCISSWWRXXX 4066
+ C C ++ + CV + C F C + CI+ W+
Sbjct: 2670 ------GPNGAECQCPHEGNWYLANDNKYCVVDTGTRCNQLQFTCLNGH-CINQDWKCDN 2722
Query: 4065 XXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDE 3886
+ VC C + F CG +C+ CD DC DE
Sbjct: 2723 DNDCGDGSDE---LPTVCAFHTCRSTAFTCG------NGRCVPYHYRCDYYNDCGDNSDE 2773
Query: 3885 EPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDC--DDGSDELNCEITSCKPDFFACF 3712
N T +F C + +CIPL+ VC+ +C +D SDE NC +C PDF C
Sbjct: 2774 AGCLFRNCNST-TEFTCSN-GRCIPLSYVCNGINNCHDNDTSDEKNCPPHTCPPDFTKC- 2830
Query: 3711 NGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTS-GKCIPKRRQCDGT 3535
+ C+P+ F CDG++DC +G DE C +FQC S +CIP CDG
Sbjct: 2831 --QTTNICVPRAFLCDGDNDCGDGSDENPIYCASHTCRSNEFQCLSPQRCIPSYWFCDGE 2888
Query: 3534 LDCRDGSDEK-------GCKKECAIVCDNS-CVHADDLCDGKKKCNDGSDEDE------E 3397
DC DGSDE + CDN C+ + +CDG C D SDED+ +
Sbjct: 2889 ADCADGSDEPDTCGHSVNTCRASQFQCDNGRCISGNWVCDGDNDCGDMSDEDQRHHCELQ 2948
Query: 3396 ACVIKQLL----EKENRKC--GGFACDGIVDCEDGSDE-KGCPDLECHLAS--------- 3265
C Q NR+C + CDG DC D DE + C C
Sbjct: 2949 NCSSTQFTCVNSRPPNRRCIPQYWVCDGDADCSDALDELQNCTMRTCSAGEFSCANGRCV 3008
Query: 3264 NKSLICDGTIDCSSGKDENNC-HNNGESNFFQC-SMQTIKEWQVCDGRWDCADGLDESPE 3091
+S CD DC DE C + +N F C + + I + VCD DC DG DE
Sbjct: 3009 RQSFRCDRRNDCGDYSDERGCSYPPCHANQFTCQNGRCIPRFFVCDEDNDCGDGSDEQEH 3068
Query: 3090 MCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKGKYRCTNGR 2911
+C + + C + D C+++ +C+ + DC D SDE + +
Sbjct: 3069 LCHTPEPTCPLHQFRCDNGHCIEMG-RVCNHVDDCSDNSDEKGCGINECLDSSISRCDHN 3127
Query: 2910 CIDVSARXXXXXXXXXXXXXXXXGA----ECHHF-GVCAQKCWMAFNHTARCHCAPGYAR 2746
C D EC +C+QKC + C CAPGY R
Sbjct: 3128 CTDTITSFYCSCLPGYKLMSDKRSCVDIDECKESPQLCSQKCENVVG-SYICKCAPGYIR 3186
Query: 2745 TKNDENECEPLSKSAEMFITNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVF 2566
+ D C + + E ++ NR ++ +L S +++ + + + +D
Sbjct: 3187 -EPDGKSCRQ-NSNIEPYLIFSNRYYIRNLTTDGSS-----YSLILQGLGNVVALDFDRV 3239
Query: 2565 RTTLMYTVGIGNSRVD--IRSKKWSDGLIGSWGEEESTAGLITYDFMHNNVYFTESSEQN 2392
L Y + ++ +K + +I A + D++ +Y+ ++
Sbjct: 3240 EKRL-YWIDAEKQIIERMFLNKTNRETII---NHRLRRAESLAVDWVSRKLYWLDAILDC 3295
Query: 2391 RGV--LFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILSA 2218
V L R + D + + G + + P + ++W I
Sbjct: 3296 LFVSDLEGRHRKMIAQHCVDANNTFCFEHPRG----IVLHPQRGHVYWADWGVHAYIGRI 3351
Query: 2217 NLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRD 2038
+DG ++ I P ++ +D++N+ LYW D IE +G
Sbjct: 3352 GMDG-----------TNKSVIISTKIEWPNAITIDYTNDLLYWADAHLGYIEFSDLEGHH 3400
Query: 2037 RRTVRKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGKTNKYVQKIREVSPRIQIR 1861
R TV L P + + ++ ++ + +K+ G V + I
Sbjct: 3401 RHTVYDGSL-PHPFALTIFEDTVFWTDWNTRTVEKGNKYDGSGR--VVLVNTTHKPFDIH 3457
Query: 1860 VAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCM 1681
V HP + + NPC ++ + +C+ G C C P F + +
Sbjct: 3458 VYHPYRQPI-----MSNPCGTNNGGCSHLCLIKAGGRGF---TCAC-PDDF------QTV 3502
Query: 1680 QLREKDQEASQCG--DYFCYNNAGCSP-------QKTC--------VCPPGFYGRQCEIN 1552
QLR++ C + C NN C P QK C +CP F C +
Sbjct: 3503 QLRDRTLCMPMCSSTQFLCGNNEKCIPIWWKCDGQKDCSDGSDEPDLCPHRF----CRLG 3558
Query: 1551 ECSETCWNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDE 1372
+ C +G C + C S+ + C + CE C C
Sbjct: 3559 QFQ--CRDG-NCTSPQALCNARQDCADGSDEDRVLCEHHRCE---SNEWQCANKRCIPQS 3612
Query: 1371 PHCRSYSFCECDKGWTGPHCRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLTGNRC 1192
C S + C + HC + + C +G ++ CGD +
Sbjct: 3613 WQCDSVNDCLDNSDEDTSHCASRT-CRPGQFKCNNGRCIPQSWKCDVDNDCGD-YSDEPI 3670
Query: 1191 QNC--VGHECLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDITK 1018
C + C N S + R +P +GF D C + + C
Sbjct: 3671 DECTTAAYNCDNHTEFSCKTNYRCIPQWAVCNGF--DDCRDNSDEQGC------------ 3716
Query: 1017 PMDPITCSCEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKC-----KCLPRFAG 853
+ + C + N C P+ K G + P +C +C +
Sbjct: 3717 --ESVPCHPSGDFRCANHHCIPLRWKCDGTDDCGDNSDEENCVPRECSESEFRCADQQCI 3774
Query: 852 PR---CDVPVQC-DDYCTNNSKCTITNGTHFEC---DCKPGFKGLRCEQETKCSECSNEA 694
P CD C D+ + + + HF+C C P K L C+ C + S+E+
Sbjct: 3775 PSRWVCDQENDCGDNSDERDCEMKTCHPEHFQCTSGHCVP--KALACDGRADCLDASDES 3832
Query: 693 KC-IKKPSGTVICQCPQGLGGEYCEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCS 517
C + P+GT CP + ECKN +C
Sbjct: 3833 ACPTRFPNGT---YCPAAM---------------FECKNH-----------------VCI 3857
Query: 516 PGFKGLLCSSNACENFCLHDGNCTLDEYFEPQCECYQAFIGD--RCQYRIHQHAVIFSDD 343
F +C EN C+ + + F CE Q F D RC ++ H + D
Sbjct: 3858 QSF--WICDG---ENDCVDGSDEEIHLCFNIPCESPQRFRCDNSRC---VYGHQLCNGVD 3909
Query: 342 DSG 334
D G
Sbjct: 3910 DCG 3912
Score = 338 bits (868), Expect = 8e-91
Identities = 224/710 (31%), Positives = 335/710 (46%), Gaps = 14/710 (1%)
Frame = -1
Query: 6252 CIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQ 6073
CI SW+CDGT DC D +DE C PRSC++ F C A TC+P W
Sbjct: 40 CIPASWRCDGTRDCLDDTDEIGC------------PPRSCESGL-FLCPAEGTCIPSSWV 86
Query: 6072 CDGQPDCADGSDEK-NCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCE-T 5899
CD DC+DG+DE+ NC C++ + +C S+ +CIP E +CD DCPDG DE C
Sbjct: 87 CDEDKDCSDGADEQQNCAGTTCSAQQMTC-SNGQCIPSEYRCDHVSDCPDGSDERNCHYP 145
Query: 5898 ECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCAD 5719
CD C N C + RCD DC D+ SDE +C C
Sbjct: 146 TCDQ------LTCANGACYNTSQRCDQKVDCRDS-----SDEANCTT--LCSQKEFECGS 192
Query: 5718 ETCVVACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASVD 5539
C+ L A +CD DC D DE+NC + D C +++ C +GQCI+ +CD D
Sbjct: 193 GECI----LRAYVCDHDNDCEDNSDERNC-NYD-TCGGHQFTCSNGQCINQNWVCDGDDD 246
Query: 5538 CVDGSDEWVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDN 5359
C D DE + C ++ R P W+C G+ C+ ++CDG DC G DE
Sbjct: 247 CQDSGDE--DGCESNQSHHRCYPREWAC---PGSGRCISIDKVCDGVPDCPEGDDENNVT 301
Query: 5358 PQGNCS-STRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCP-KANCSHFC 5185
C + + + C + C C G+ ++ D +TC+ C C C
Sbjct: 302 SGRTCGMGVCSVLNCEYQCHQTPFGGECFCPPGHIINSNDSRTCIDFDDCQIWGICDQKC 361
Query: 5184 IDRRDVGHQCFCAPGYILSENQKDCRRNDTIE-AEILMVYGHRLKLFTIDGHAKATLLSN 5008
+ R HQC C GYIL Q C+ +D+ A ++ G L + + G L +
Sbjct: 362 -ENRQGRHQCLCEEGYILERGQ-HCKSSDSFSAASVIFSNGRDLLVGDLHGRNFRILAES 419
Query: 5007 LTNGVAL--DYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVIN-SLPTKGIDGIAVD 4837
G+ + D+ + V+WTD + K T + N NT ++N S+ T + +AVD
Sbjct: 420 KNRGMVMGVDFHYQKHRVFWTDPMQE--KVFSTDI-NGLNTQEILNVSVDTP--ENLAVD 474
Query: 4836 WLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGA--- 4666
W+ +Y + + I V ++ G R+ L L PR I LDP +F++DWG+
Sbjct: 475 WINNKLYLVETKVNRIDVVNLEGN-QRVTLITENLGHPRGIALDPTVGYLFFSDWGSLSG 533
Query: 4665 SAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRM 4486
+ R MDGSN + ++ + + WP + +D ++R+Y+ D+ DYI + YDG +R+
Sbjct: 534 QPKVERAFMDGSNRKDLVTTK-VGWPAGITLDLVSKRVYWVDSRYDYIETVTYDGIQRKT 592
Query: 4485 VLRGS--VRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVH 4312
V RG V H F +++FE++V+++DW + + K T TN +V Q RP G + H
Sbjct: 593 VARGGSLVPHPFGISLFEEHVFFTDWTKMAVMKASKFTETNPQVYHQ-SSLRPHGVTVYH 651
Query: 4311 PSLQSMGSLKTARHPC-SQPARCDNLCIPANTPDLTTSSDNFTCMCAQGF 4165
Q A +PC S C +C+ ++ D + C C GF
Sbjct: 652 ALRQ-----PNATNPCGSNNGGCAQVCVLSHRTD--NGGLGYRCKCEFGF 694
Score = 279 bits (714), Expect = 6e-73
Identities = 237/821 (28%), Positives = 342/821 (40%), Gaps = 62/821 (7%)
Frame = -1
Query: 5199 CSHFCI-----DRRDVGHQCFCAPGYILSENQKDCR--RNDTIEAEILMVYGHRLKLFTI 5041
C+ C+ D +G++C C G+ L +++ C +N + + V G L T
Sbjct: 669 CAQVCVLSHRTDNGGLGYRCKCEFGFELDDDEHRCVAVKNFLLFSSKTAVRGIPFTLSTQ 728
Query: 5040 DGHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTK 4861
+ + + + V +D+D + V+++D++ D I VI + +
Sbjct: 729 ED-VMVPVTGSPSFFVGIDFDAQHSTVFYSDLSKDI----IYKQKIDGTGKEVITANRLE 783
Query: 4860 GIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFW 4681
++ + DW+ RN+Y+TD ++ V + + R ++ LN+PR+IV+ P +F
Sbjct: 784 SVECLTFDWISRNLYWTDGGLKSVTVLRLADKSRRQIISN--LNNPRSIVVHPTAGYMFL 841
Query: 4680 TDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDG 4501
+DW A I R DGS+ I+ + ++ WPN LA+D A RLY+ DA D I DG
Sbjct: 842 SDWFRPAKIMRAWSDGSHLMPIV-NTSLGWPNGLAIDWSASRLYWVDAFFDKIEHSTLDG 900
Query: 4500 -SKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGF 4324
++R+ + H F L VF+D V+ +DW I RV K G + V+ + G
Sbjct: 901 LDRKRLGHVDQMTHPFGLTVFKDNVFITDWRLGAIIRVRKSDGGDMTVIRR-------GI 953
Query: 4323 KIVHPSLQSMGSLKTARHPCSQPAR----CDNLCIPANTPDLTTSSDNF--TCMCAQGFR 4162
V L+T + CSQ C + C P NF C C G +
Sbjct: 954 SSVMHVKAYDADLQTGSNYCSQTTHANGDCSHFCFPV---------PNFQRVCGCPYGMK 1004
Query: 4161 --SEGRSC---------VSECKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGV 4015
+ +C +C F C KC+ S++R E
Sbjct: 1005 LQRDQMTCEGDPAREPPTQQCGSLSFPCNNG-KCVPSFFRCDGVDDCHDNSD-----EHQ 1058
Query: 4014 CPPF--PCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEE--PAFCENFECTEA 3847
C F C F C R QC+ CD DC G DE+ P + C
Sbjct: 1059 CGVFNNTCSPSAFACVR-----GGQCIPGQWHCDRQNDCLDGSDEQNCPTHATSSTCPST 1113
Query: 3846 QFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEIT-SCKPDFFACFNGTAISKCIPKEFY 3670
F C D CIP VCD + DC DGSDE NC+ + +C+P F C + +CI +
Sbjct: 1114 SFTC-DNHVCIPKDWVCDTDNDCSDGSDEKNCQASGTCQPTQFRCPD----HRCISPLYV 1168
Query: 3669 CDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSG-KCIPKRRQCDGTLDCRDGSDEKGCKK 3493
CDG+ DC +G DE + CT QF+C G CI R +CDG DCRD SDE GC
Sbjct: 1169 CDGDKDCADGSDEAGC---VLNCTSAQFKCADGSSCINSRYRCDGVYDCRDNSDEAGCPT 1225
Query: 3492 ECAIVC---------DNSCVHADDLCDGKKKCNDGSDEDEEACVIKQ------LLEKENR 3358
+C D +C+ CDG C GSDE CV K L + N
Sbjct: 1226 RPPGMCHPDEFQCQGDGTCIPNTWECDGHPDCIHGSDE-HTGCVPKTCSPTHFLCDNGNC 1284
Query: 3357 KCGGFACDGIVDCEDGSDEKGCPDLECHLAS------------NKSLICDGTIDCSSGKD 3214
+ CDG DC D SDEK CP H S N S +CDG DC +G D
Sbjct: 1285 IYKAWICDGDNDCRDMSDEKDCPTQPFHCPSTQWQCPGYSTCINLSALCDGVFDCPNGTD 1344
Query: 3213 ENNCHNNGESNFFQ--CSMQTIKEWQVCDGRWDCADGLDESPEMCASRKARCFRIGY--C 3046
E+ N + F C+ Q C G + +C +GY
Sbjct: 1345 ESPLCNQDSCSHFNGGCTHQ-------------CMQGPFGATCLCP--------LGYQLA 1383
Query: 3045 DDKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKGKYRC 2923
+D K C D++ CD C HC +M +G +RC
Sbjct: 1384 NDTKTCEDINE--CDIPGFCSQ-------HCVNM-RGSFRC 1414
Score = 225 bits (573), Expect = 1e-56
Identities = 202/769 (26%), Positives = 305/769 (39%), Gaps = 39/769 (5%)
Frame = -1
Query: 3861 ECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCKPDFFACFNGTAISKCIP 3682
EC F+C D CIP + CD +DC D +DE+ C SC+ F C A CIP
Sbjct: 27 ECGSGNFRC-DNGYCIPASWRCDGTRDCLDDTDEIGCPPRSCESGLFLC---PAEGTCIP 82
Query: 3681 KEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQCDGTLDCRDGSDEKG 3502
+ CD + DC +G DE +C G C+ +Q C++G+CIP +CD DC DGSDE+
Sbjct: 83 SSWVCDEDKDCSDGADEQQNCAGT-TCSAQQMTCSNGQCIPSEYRCDHVSDCPDGSDERN 141
Query: 3501 CKKECA--IVCDN-SCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKENRKCG------ 3349
C + C N +C + CD K C D SDE L ++ +CG
Sbjct: 142 CHYPTCDQLTCANGACYNTSQRCDQKVDCRDSSDEAN----CTTLCSQKEFECGSGECIL 197
Query: 3348 -GFACDGIVDCEDGSDEKGCPDLEC---------HLASNKSLICDGTIDCSSGKDENNCH 3199
+ CD DCED SDE+ C C N++ +CDG DC DE+ C
Sbjct: 198 RAYVCDHDNDCEDNSDERNCNYDTCGGHQFTCSNGQCINQNWVCDGDDDCQDSGDEDGCE 257
Query: 3198 NNGESNFFQCSMQTIKEWQVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCLDV 3019
+N +S C R+ C G +C+ +
Sbjct: 258 SN------------------------------QSHHRCYPREWACPGSG------RCISI 281
Query: 3018 STALCDGIRDCFDGSDENPIHCKDMC--------KGKYRC----TNGRCIDVSARXXXXX 2875
+CDG+ DC +G DEN + C +Y+C G C
Sbjct: 282 D-KVCDGVPDCPEGDDENNVTSGRTCGMGVCSVLNCEYQCHQTPFGGECFCPPGHIINSN 340
Query: 2874 XXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTAR--CHCAPGYARTKNDENECEPLSKSA 2701
+C +G+C QKC N R C C GY + + +A
Sbjct: 341 DSRTCIDFD----DCQIWGICDQKC---ENRQGRHQCLCEEGYILERGQHCKSSDSFSAA 393
Query: 2700 EMFITNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRV 2521
+ +NG L + L +L N M + G+DF Y R +
Sbjct: 394 SVIFSNGRDLLVGDLHGRNFRILAESKNRGMVM---GVDFHYQKHRVFWTDPMQEKVFST 450
Query: 2520 DIRSKKWSDGLIGSWGEEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAK 2341
DI + L S E+ A D+++N +Y E ++ NR I V +
Sbjct: 451 DINGLNTQEILNVSVDTPENLA----VDWINNKLYLVE-TKVNR---------IDVVNLE 496
Query: 2340 DTSTRTLIVNSTGTINSLAVDPIKRLIF---WTTSAPVPRILSANLDGKPIAQPFKTGSQ 2170
TLI + G +A+DP +F W + + P++ A +DG
Sbjct: 497 GNQRVTLITENLGHPRGIALDPTVGYLFFSDWGSLSGQPKVERAFMDG-----------S 545
Query: 2169 PHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTV-RKFELGDTPVT 1993
K LV + P + LD ++R+YW+D IETV++DG R+TV R L P
Sbjct: 546 NRKDLVTTKVGWPAGITLDLVSKRVYWVDSRYDYIETVTYDGIQRKTVARGGSLVPHPFG 605
Query: 1992 MDVLGGYIYLIT-RQGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQ 1816
+ + +++ + ++ + KFT +TN V + P + V H + +
Sbjct: 606 ISLFEEHVFFTDWTKMAVMKASKFT-ETNPQVYHQSSLRPH-GVTVYHALRQ-----PNA 658
Query: 1815 KNPCQSDYCPSNTVCV-PDQDKNGILIPKCLCGPGRFFEVSTKKCMQLR 1672
NPC S+ VCV + NG L +C C G + +C+ ++
Sbjct: 659 TNPCGSNNGGCAQVCVLSHRTDNGGLGYRCKCEFGFELDDDEHRCVAVK 707
Score = 165 bits (417), Expect = 2e-38
Identities = 103/303 (33%), Positives = 137/303 (44%), Gaps = 24/303 (7%)
Frame = -1
Query: 3999 CIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKK 3820
C +G F C C+ AS CDG +DC DD + C C F C +
Sbjct: 28 CGSGNFRCDN------GYCIPASWRCDGTRDCL--DDTDEIGCPPRSCESGLFLCPAEGT 79
Query: 3819 CIPLTSVCDKEKDCDDGSDE-LNCEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPE 3643
CIP + VCD++KDC DG+DE NC T+C C NG +CIP E+ CD DCP+
Sbjct: 80 CIPSSWVCDEDKDCSDGADEQQNCAGTTCSAQQMTCSNG----QCIPSEYRCDHVSDCPD 135
Query: 3642 GQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQCDGTLDCRDGSDEKGCKKECA---IVC- 3475
G DE + + T +Q C +G C ++CD +DCRD SDE C C+ C
Sbjct: 136 GSDERNCHYP----TCDQLTCANGACYNTSQRCDQKVDCRDSSDEANCTTLCSQKEFECG 191
Query: 3474 DNSCVHADDLCDGKKKCNDGSDE---DEEACVIKQLLEKENRKC--GGFACDGIVDCEDG 3310
C+ +CD C D SDE + + C Q N +C + CDG DC+D
Sbjct: 192 SGECILRAYVCDHDNDCEDNSDERNCNYDTCGGHQ-FTCSNGQCINQNWVCDGDDDCQDS 250
Query: 3309 SDEKGCPDLECH----------LASNKSL----ICDGTIDCSSGKDENNCHNNGESNFFQ 3172
DE GC + H S + + +CDG DC G DENN +
Sbjct: 251 GDEDGCESNQSHHRCYPREWACPGSGRCISIDKVCDGVPDCPEGDDENNVTSGRTCGMGV 310
Query: 3171 CSM 3163
CS+
Sbjct: 311 CSV 313
Score = 154 bits (388), Expect = 4e-35
Identities = 110/368 (29%), Positives = 154/368 (40%), Gaps = 25/368 (6%)
Frame = -1
Query: 4137 ECKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQN 3958
EC +F C Y CI + WR E CPP C +G F+C
Sbjct: 27 ECGSGNFRCDNGY-CIPASWRCDGTRDCLDDTD-----EIGCPPRSCESGLFLC-----P 75
Query: 3957 ATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDC 3778
A C+ +S +CD KDCS G DE+ C C+ Q C + +CIP CD DC
Sbjct: 76 AEGTCIPSSWVCDEDKDCSDGADEQQN-CAGTTCSAQQMTCSN-GQCIPSEYRCDHVSDC 133
Query: 3777 DDGSDELNCEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECT 3598
DGSDE NC +C D C NG C CD + DC + DE +C + C+
Sbjct: 134 PDGSDERNCHYPTC--DQLTCANGA----CYNTSQRCDQKVDCRDSSDEA-NCTTL--CS 184
Query: 3597 HEQFQCTSGKCIPKRRQCDGTLDCRDGSDEKGCKKECA----IVCDN-SCVHADDLCDGK 3433
++F+C SG+CI + CD DC D SDE+ C + C N C++ + +CDG
Sbjct: 185 QKEFECGSGECILRAYVCDHDNDCEDNSDERNCNYDTCGGHQFTCSNGQCINQNWVCDGD 244
Query: 3432 KKCNDGSDED-------EEACVIKQLLEKENRKCGGF--ACDGIVDCEDGSDEKG----- 3295
C D DED C ++ + +C CDG+ DC +G DE
Sbjct: 245 DDCQDSGDEDGCESNQSHHRCYPREWACPGSGRCISIDKVCDGVPDCPEGDDENNVTSGR 304
Query: 3294 ------CPDLECHLASNKSLICDGTIDCSSGKDENNCHNNGESNFFQCSMQTIKEWQVCD 3133
C L C +++ G C G N+ + +F C + W +CD
Sbjct: 305 TCGMGVCSVLNCEYQCHQTPF-GGECFCPPGHIINSNDSRTCIDFDDCQI-----WGICD 358
Query: 3132 GRWDCADG 3109
+ + G
Sbjct: 359 QKCENRQG 366
Score = 149 bits (377), Expect = 7e-34
Identities = 77/226 (34%), Positives = 117/226 (51%), Gaps = 7/226 (3%)
Frame = -1
Query: 6567 EDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC---TCNENEFRCQSG 6397
++ + C+ C C NG CIP + C+ ++DC + +DE NC TC ++ C +G
Sbjct: 98 DEQQNCAGTTCSAQQMTCSNGQCIPSEYRCDHVSDCPDGSDERNCHYPTC--DQLTCANG 155
Query: 6396 ACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDGTN 6217
AC + RC+ DC D+SDE C + EF C + +CI ++ CD N
Sbjct: 156 ACYNTSQRCDQKVDCRDSSDEANC--TTLCSQKEF------ECG-SGECILRAYVCDHDN 206
Query: 6216 DCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADGSD 6037
DC D SDE++C +D GG QF C + C+ ++W CDG DC D D
Sbjct: 207 DCEDNSDERNC--NYDTCGGH-----------QFTC-SNGQCINQNWVCDGDDDCQDSGD 252
Query: 6036 EKNCDAK----KCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEH 5911
E C++ +C E++C S +CI +++ CDG DCP+G+DE+
Sbjct: 253 EDGCESNQSHHRCYPREWACPGSGRCISIDKVCDGVPDCPEGDDEN 298
Score = 149 bits (377), Expect = 7e-34
Identities = 92/253 (36%), Positives = 121/253 (47%), Gaps = 10/253 (3%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC---TCNENEFRCQ 6403
D+ D + C R C F C + CIP + VC++ NDC + +DE +C TC+ F+C
Sbjct: 3749 DNSDEENCVPRECSESEFRCADQQCIPSRWVCDQENDCGDNSDERDCEMKTCHPEHFQCT 3808
Query: 6402 SGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDG 6223
SG C+P C+ DC DASDE CP R + + + C CI W CDG
Sbjct: 3809 SGHCVPKALACDGRADCLDASDESACPTRFPN--GTYCPAAMFEC-KNHVCIQSFWICDG 3865
Query: 6222 TNDCYDGSDEKD--CFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCA 6049
NDC DGSDE+ CF + P C++ +F C +R C+ H C+G DC
Sbjct: 3866 ENDCVDGSDEEIHLCF----------NIP--CESPQRFRCDNSR-CVYGHQLCNGVDDCG 3912
Query: 6048 DGSDEKNCDAKK-----CTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSK 5884
DGSDEK +K CT E+ C S+ CI CD DC D DE C +
Sbjct: 3913 DGSDEKEEHCRKPTHKPCTDTEYKC-SNGNCISQHYVCDNVNDCGDLSDETGC-----NL 3966
Query: 5883 GGNATFRCTNHRC 5845
G N T C + C
Sbjct: 3967 GDNRT--CAENIC 3977
Score = 140 bits (352), Expect = 5e-31
Identities = 106/380 (27%), Positives = 180/380 (46%), Gaps = 19/380 (5%)
Frame = -1
Query: 5226 RSPSCPKANCSHFCIDRRDVG--HQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLK 5053
R+P C A+CSH C+ + C C G+ LS++ +C R D + ++ V + +
Sbjct: 1702 RNP-CASASCSHLCLLSAQAPRHYSCACPSGWNLSDDSVNCVRGD--QPFLMSVRDNIIF 1758
Query: 5052 LFTIDGHAKAT----LLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYR 4885
++D K+ +S + +G +++D +YW + N I + +
Sbjct: 1759 GISLDPEVKSNDAMVPISGIQHGYDVEFDDSEQFIYWVE-----NPGEIHRVKTDGSNRT 1813
Query: 4884 VINSLPTKGID-GIAVDWLGRNIYYTDRNHDAIAVCDMRG--RFNRILLK--GTPLND-- 4726
V L G G+A+DW+ RNIYYT +I V ++G R+ + L+ GTPL
Sbjct: 1814 VFAPLSLLGSSLGLALDWVSRNIYYTTPASRSIEVLTLKGDTRYGKTLIANDGTPLGVGF 1873
Query: 4725 PRAIVLDPLQALVFW----TDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQ 4558
P I +DP + ++W TD G A I NMDG++ +++ ++ + +D Q
Sbjct: 1874 PVGIAVDPARGKLYWSDHGTDSGVPAKIASANMDGTSLKILFTGN-LQHLEVVTLDIQEQ 1932
Query: 4557 RLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKIT 4378
+LY+ R I N DG++R M+L + H + L V+ ++Y+SD IERV K +
Sbjct: 1933 KLYWAVTSRGVIERGNVDGTER-MILVHHLAHPWGLVVYGSFLYYSDEQYEVIERVDKSS 1991
Query: 4377 GTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDNLCIPANTPDLTTSS 4198
G N KV+++D G ++ H + ++ + P C +C+P
Sbjct: 1992 G-NNKVVLRDNVPYLRGLRVYH----RRNAADSSNGCSNNPNACQQICLP-------VPG 2039
Query: 4197 DNFTCMCAQGFR--SEGRSC 4144
F+C CA GF+ +GRSC
Sbjct: 2040 GMFSCACASGFKLSPDGRSC 2059
Score = 137 bits (344), Expect = 5e-30
Identities = 168/719 (23%), Positives = 250/719 (34%), Gaps = 113/719 (15%)
Frame = -1
Query: 3606 ECTHEQFQCTSGKCIPKRRQCDGTLDCRDGSDEKGC---KKEC-----AIVCDNSCVHAD 3451
+C F C +GKC+P +CDG DC D SDE C C A V C+
Sbjct: 1024 QCGSLSFPCNNGKCVPSFFRCDGVDDCHDNSDEHQCGVFNNTCSPSAFACVRGGQCIPGQ 1083
Query: 3450 DLCDGKKKCNDGSDEDE------EACVIKQLLEKENRKC--GGFACDGIVDCEDGSDEKG 3295
CD + C DGSDE + +N C + CD DC DGSDEK
Sbjct: 1084 WHCDRQNDCLDGSDEQNCPTHATSSTCPSTSFTCDNHVCIPKDWVCDTDNDCSDGSDEKN 1143
Query: 3294 C--------PDLEC--HLASNKSLICDGTIDCSSGKDENNCHNNGESNFFQCS--MQTIK 3151
C C H + +CDG DC+ G DE C N S F+C+ I
Sbjct: 1144 CQASGTCQPTQFRCPDHRCISPLYVCDGDKDCADGSDEAGCVLNCTSAQFKCADGSSCIN 1203
Query: 3150 EWQVCDGRWDCADGLDES------PEMCASRKARCFRIG-------YCDDKKQCLDVSTA 3010
CDG +DC D DE+ P MC + +C G CD C+ S
Sbjct: 1204 SRYRCDGVYDCRDNSDEAGCPTRPPGMCHPDEFQCQGDGTCIPNTWECDGHPDCIHGSDE 1263
Query: 3009 --------------------------LCDGIRDCFDGSDE-----NPIHCKD---MCKGK 2932
+CDG DC D SDE P HC C G
Sbjct: 1264 HTGCVPKTCSPTHFLCDNGNCIYKAWICDGDNDCRDMSDEKDCPTQPFHCPSTQWQCPGY 1323
Query: 2931 YRCTNGRCIDVSARXXXXXXXXXXXXXXXXGAECHHF-GVCAQKCWMAFNHTARCHCAPG 2755
C N + C HF G C +C M A C C G
Sbjct: 1324 STCIN---LSALCDGVFDCPNGTDESPLCNQDSCSHFNGGCTHQC-MQGPFGATCLCPLG 1379
Query: 2754 YARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGY 2575
Y + ND CE ++ E I H +++ S P + ++ + G
Sbjct: 1380 Y-QLANDTKTCEDIN---ECDIPGFCSQHCVNMRGSFRCACDPEYTLESD----GRTCKV 1431
Query: 2574 DVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGLITYDFMHNNVYFTESSEQ 2395
L+ VD + + + S ++ S + +D + V++++ +
Sbjct: 1432 TGSENPLLVVASRDKIIVDNITAHTHN--LYSLVQDVSFVVALDFDSVTGRVFWSDLLQG 1489
Query: 2394 NRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILSAN 2215
+F T R + + +AVD I R ++WT A + I +
Sbjct: 1490 KTWSVFQ----------NGTDKRVVHDSGLSVTEMIAVDWIGRNLYWTDYA-LETIEVSK 1538
Query: 2214 LDG--------KPIAQPFKTGSQP---------------------------HKALVERNI 2140
+DG K + +P P +V+ I
Sbjct: 1539 IDGSHRTVLISKNVTKPRGLALDPRMGDNVMFWSDWGHHPRIERASMDGTMRTVIVQEKI 1598
Query: 2139 FEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELG-DTPVTMDVLGGYIYL 1963
+ P + +D+ N +Y++D IE +DG +RR V +L P + + ++Y
Sbjct: 1599 YWPCGLSIDYPNRLIYFMDAYLDYIEFCDYDGHNRRQVIASDLVLHHPHALTLFEDFVYW 1658
Query: 1962 ITR-QGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYC 1789
R + + +K+ G V + V + I HP++ S +NPC S C
Sbjct: 1659 TDRGTRQVMQANKWHGGNQSVV--MYSVHQPLGITAIHPSRQPPS-----RNPCASASC 1710
Score = 130 bits (327), Expect = 4e-28
Identities = 91/258 (35%), Positives = 120/258 (46%), Gaps = 18/258 (6%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADES---NC---TCNENEF 6412
D+ DT S CR F C NG CI VC+ NDC + +DE +C C+ +F
Sbjct: 2896 DEPDTCGHSVNTCRASQFQCDNGRCISGNWVCDGDNDCGDMSDEDQRHHCELQNCSSTQF 2955
Query: 6411 RCQSG-----ACIPSKARCNHMQDCNDASDEI-GCPFRNCSALNEFGMTGLINCATTSQC 6250
C + CIP C+ DC+DA DE+ C R CSA G +CA +C
Sbjct: 2956 TCVNSRPPNRRCIPQYWVCDGDADCSDALDELQNCTMRTCSA-------GEFSCA-NGRC 3007
Query: 6249 IHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQC 6070
+ S++CD NDC D SDE+ C S P C A QF C R C+P+ + C
Sbjct: 3008 VRQSFRCDRRNDCGDYSDERGC-----------SYP-PCHA-NQFTCQNGR-CIPRFFVC 3053
Query: 6069 DGQPDCADGSDEKN--CDAKK--CTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCE 5902
D DC DGSDE+ C + C +F C++ CI + + C+ DC D DE C
Sbjct: 3054 DEDNDCGDGSDEQEHLCHTPEPTCPLHQFRCDNG-HCIEMGRVCNHVDDCSDNSDEKGCG 3112
Query: 5901 -TEC-DSKGGNATFRCTN 5854
EC DS CT+
Sbjct: 3113 INECLDSSISRCDHNCTD 3130
Score = 112 bits (279), Expect = 2e-22
Identities = 97/376 (25%), Positives = 165/376 (43%), Gaps = 11/376 (2%)
Frame = -1
Query: 5232 CLRSPSCPKANCSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILM--VYGHR 5059
C +P+ C C+ C CA G+ LS + + C ++ ++ V G
Sbjct: 2023 CSNNPNA----CQQICLPVPGGMFSCACASGFKLSPDGRSCSPYNSFMVVSMLPAVRGFS 2078
Query: 5058 LKLFTIDGHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKA-GITSMSNQPNTYR- 4885
L+L + A + N + D DV + +YW D + + GI + + +
Sbjct: 2079 LEL-SDHSEAMVPVAGQGRNVLHADVDVANGFIYWCDFSSSVRSSNGIRRIKPDGSNFTN 2137
Query: 4884 -VINSLPTKGIDGIAVDWLGRNIYYTDR--NHDAIAVCDMRGRFNRILLKGTPLNDPRAI 4714
V + GI G+A+DW N+Y+T+ I V + + R+LLK ++ PR I
Sbjct: 2138 VVTYGIGANGIRGVALDWAAGNLYFTNAFVYETLIEVLRINTTYRRVLLK-VSVDMPRHI 2196
Query: 4713 VLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAH 4534
++DP +FW D+G I R +D +N V++ + + P LA+D +Y+ D
Sbjct: 2197 IVDPKHRYLFWADYGQKPKIERSFLDCTNRTVLVSEGIVT-PRGLAMDHDTGYIYWVDDS 2255
Query: 4533 RDYIASCNYDGSKRRMVLRGS-VRHIFALAVFEDYVYWSDWHNHTIERVHKITG-TNRKV 4360
D IA + DG + ++V GS + + VF + + W D + + + K G T+ V
Sbjct: 2256 LDLIARIHLDGGESQVVRYGSRYPTPYGITVFGESIIWVDRNLKKVFQASKQPGNTDPPV 2315
Query: 4359 LIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQP-ARCDNLCIPANTPDLTTSSDNFTC 4183
+I+DK I Q + + +PC Q C + C P+L T C
Sbjct: 2316 VIRDKINLLRDVTIFDEHAQPLSPAELNNNPCLQSNGGCSHFCFA--LPELPTP----RC 2369
Query: 4182 MCAQG-FRSEGRSCVS 4138
CA G ++G+SC +
Sbjct: 2370 GCAFGTLGNDGKSCAT 2385
Score = 100 bits (248), Expect = 6e-19
Identities = 74/248 (29%), Positives = 107/248 (42%), Gaps = 17/248 (6%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCT--------CNEN 6418
D+ D + C + C P +F C +G C+P+ C+ DC + +DES C C
Sbjct: 3788 DNSDERDCEMKTCHPEHFQCTSGHCVPKALACDGRADCLDASDESACPTRFPNGTYCPAA 3847
Query: 6417 EFRCQSGACIPSKARCNHMQDCNDASD-EIGCPFR-NCSALNEFGMTGLINCATTSQCIH 6244
F C++ CI S C+ DC D SD EI F C + F S+C++
Sbjct: 3848 MFECKNHVCIQSFWICDGENDCVDGSDEEIHLCFNIPCESPQRFR-------CDNSRCVY 3900
Query: 6243 PSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDG 6064
C+G +DC DGSDEK+ + C T++ C + C+ +H+ CD
Sbjct: 3901 GHQLCNGVDDCGDGSDEKEEHCR-------KPTHKPC-TDTEYKC-SNGNCISQHYVCDN 3951
Query: 6063 QPDCADGSDEKNCD-AKKCTSFEFSCESSKKCIPLEQK---CDGRRDC-PDGEDEHQCE- 5902
DC D SDE C+ T E CE + C L C R P D++ C+
Sbjct: 3952 VNDCGDLSDETGCNLGDNRTCAENICE--QNCTQLSSGGFICSCRPGFKPSTSDKNSCQD 4009
Query: 5901 -TECDSKG 5881
EC+ G
Sbjct: 4010 INECEEFG 4017
Score = 92.4 bits (228), Expect = 1e-16
Identities = 188/848 (22%), Positives = 293/848 (34%), Gaps = 56/848 (6%)
Frame = -1
Query: 2820 GVCAQKCWMAFNHTA-----RCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSL 2656
G CAQ C ++ RC C G+ +DE+ C + K+ +F + +
Sbjct: 667 GGCAQVCVLSHRTDNGGLGYRCKCEFGF-ELDDDEHRCVAV-KNFLLFSSKTAVRGIPFT 724
Query: 2655 ENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSW 2476
++Q V+ PV + GIDF D +T+ Y+ + DI K+ DG
Sbjct: 725 LSTQEDVMVPVTGSPSFFV--GIDF--DAQHSTVFYS----DLSKDIIYKQKIDGT---- 772
Query: 2475 GEEESTAG------LITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIV 2314
G+E TA +T+D++ N+Y+T+ ++ + V + D S R +I
Sbjct: 773 GKEVITANRLESVECLTFDWISRNLYWTDGGLKS----------VTVLRLADKSRRQIIS 822
Query: 2313 NSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFE 2134
N S+ V P +F + +I+ A DG + +V ++
Sbjct: 823 NLNNP-RSIVVHPTAGYMFLSDWFRPAKIMRAWSDGSHLMP-----------IVNTSLGW 870
Query: 2133 PTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT- 1957
P + +D+S RLYW+D IE + DG DR+ + + P + V +++
Sbjct: 871 PNGLAIDWSASRLYWVDAFFDKIEHSTLDGLDRKRLGHVDQMTHPFGLTVFKDNVFITDW 930
Query: 1956 RQGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNT 1777
R G+I R+ K G ++ R +S + ++ T S+ Q D C
Sbjct: 931 RLGAIIRVRKSDGGDMTVIR--RGISSVMHVKAYDADLQTGSNYCSQTTHANGD-CSHFC 987
Query: 1776 VCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCGDY-FCYNNAGCSP-- 1606
VP+ + C C G + C ++ QCG F NN C P
Sbjct: 988 FPVPNFQR------VCGCPYGMKLQRDQMTCEGDPAREPPTQQCGSLSFPCNNGKCVPSF 1041
Query: 1605 ---QKTCVCPPGFYGRQCEI--NECSET---CWNGETCAVQEFGSTTNVVCHCPSNYTQS 1450
C QC + N CS + C G C ++ HC Q+
Sbjct: 1042 FRCDGVDDCHDNSDEHQCGVFNNTCSPSAFACVRGGQCIPGQW--------HCD---RQN 1090
Query: 1449 SCATNVCEGVCGPRGSCKTVPCPKDEPHCRSYSFCECDKGW---TGPHCRHKADAKVCYG 1279
C E C + T CP C ++ C K W T C +D K
Sbjct: 1091 DCLDGSDEQNCPTHATSST--CPSTSFTCDNH-VC-IPKDWVCDTDNDCSDGSDEK---- 1142
Query: 1278 HCFSGGACDGEGPLNLRCSCGDGLTGNRCQNCVGHECLNGGFCSYANSNRSLPHCICPSG 1099
+C + G C P RC H C++ + + + C G
Sbjct: 1143 NCQASGTCQ---PTQFRCP--------------DHRCISPLYVCDGDKD-------CADG 1178
Query: 1098 FTGDHCEEYLCKDA---CPFGSKCTYDITKPMDPITCSCEQNAAAHNTDCSPICQKQPNW 928
C C A C GS C + C + A T +C
Sbjct: 1179 SDEAGC-VLNCTSAQFKCADGSSCINSRYRCDGVYDCRDNSDEAGCPTRPPGMCHPDEFQ 1237
Query: 927 CHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSKCT--ITNGTHFECD--- 763
C G C+ CD C ++ C + THF CD
Sbjct: 1238 CQGDGTCIPNTW--------------ECDGHPDCIHGSDEHTGCVPKTCSPTHFLCDNGN 1283
Query: 762 CKPGFKGLRCEQETKCSECSNEAKCIKKP--SGTVICQCPQGLGGEYCEKITATSCHQLE 589
C +K C+ + C + S+E C +P + QCP G C ++A +
Sbjct: 1284 CI--YKAWICDGDNDCRDMSDEKDCPTQPFHCPSTQWQCP---GYSTCINLSALCDGVFD 1338
Query: 588 CKNGGYCLKPDPSANRTS------------------PTCLCSPGFKGLLCSSNACE--NF 469
C NG P N+ S TCLC G++ L + CE N
Sbjct: 1339 CPNG---TDESPLCNQDSCSHFNGGCTHQCMQGPFGATCLCPLGYQ-LANDTKTCEDINE 1394
Query: 468 CLHDGNCT 445
C G C+
Sbjct: 1395 CDIPGFCS 1402
Score = 64.7 bits (156), Expect = 3e-08
Identities = 41/146 (28%), Positives = 58/146 (39%), Gaps = 16/146 (10%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCTCNENEFRCQ--- 6403
D+ D + C+ C F C NG CI + VC+ +DC + DE C N++ RC
Sbjct: 210 DNSDERNCNYDTCGGHQFTCSNGQCINQNWVCDGDDDCQDSGDEDGCESNQSHHRCYPRE 269
Query: 6402 -----SGACIPSKARCNHMQDCNDASDEIGCPF-RNCSALNEFGMTGLINCATT------ 6259
SG CI C+ + DC + DE R C G+ ++NC
Sbjct: 270 WACPGSGRCISIDKVCDGVPDCPEGDDENNVTSGRTCG----MGVCSVLNCEYQCHQTPF 325
Query: 6258 -SQCIHPSWKCDGTNDCYDGSDEKDC 6184
+C P +ND D DC
Sbjct: 326 GGECFCPPGHIINSNDSRTCIDFDDC 351
Score = 57.8 bits (138), Expect = 4e-06
Identities = 79/372 (21%), Positives = 132/372 (35%), Gaps = 5/372 (1%)
Frame = -1
Query: 2814 CAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQVS- 2638
C Q C C CA G+ + D C P + M ++ + SLE S S
Sbjct: 2030 CQQICLPVPGGMFSCACASGF-KLSPDGRSCSPYNSF--MVVSMLPAVRGFSLELSDHSE 2086
Query: 2637 VLRPVFNIKMNLIPGGIDFGYD-VFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEES 2461
+ PV N++ +D ++ +V N I+ + + ++G +
Sbjct: 2087 AMVPVAGQGRNVLHADVDVANGFIYWCDFSSSVRSSNGIRRIKPDGSNFTNVVTYGIGAN 2146
Query: 2460 TAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAV 2281
+ D+ N+YFT + F + I V + T R L+ S + V
Sbjct: 2147 GIRGVALDWAAGNLYFTNA--------FVYETLIEVLRINTTYRRVLLKVSVDMPRHIIV 2198
Query: 2280 DPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNE 2101
DP R +FW P+I + LD LV I P + +D
Sbjct: 2199 DPKHRYLFWADYGQKPKIERSFLD-----------CTNRTVLVSEGIVTPRGLAMDHDTG 2247
Query: 2100 RLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITRQ-GSIHRMHKF 1924
+YW+D I + DG + + VR TP + V G I + R + + K
Sbjct: 2248 YIYWVDDSLDLIARIHLDGGESQVVRYGSRYPTPYGITVFGESIIWVDRNLKKVFQASKQ 2307
Query: 1923 TGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPC--QSDYCPSNTVCVPDQDKN 1750
G T+ V +++ + + +S NPC + C +P+
Sbjct: 2308 PGNTDPPVVIRDKINLLRDVTIFDEHAQPLSPAELNNNPCLQSNGGCSHFCFALPE---- 2363
Query: 1749 GILIPKCLCGPG 1714
+ P+C C G
Sbjct: 2364 -LPTPRCGCAFG 2374
Score = 56.6 bits (135), Expect = 8e-06
Identities = 52/197 (26%), Positives = 68/197 (34%), Gaps = 7/197 (3%)
Frame = -1
Query: 5679 CDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASVDCVDGSDEWVEICS 5500
CD DC DG DE C+ + C +G+C+ CD DC D SDE C
Sbjct: 2720 CDNDNDCGDGSDELPTVCAFHTCRSTAFTCGNGRCVPYHYRCDYYNDCGDNSDE--AGCL 2777
Query: 5499 LSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCM-SGIDEQCDNPQGNCSSTRNSC 5323
R C S +NG C+ +C+G +C + ++ + P C C
Sbjct: 2778 F-----RNCNSTTEFTCSNGR--CIPLSYVCNGINNCHDNDTSDEKNCPPHTCPPDFTKC 2830
Query: 5322 DQTWNCQRHAGF--ESCSCDDGYHLSPYDKKTCLRSPSCPKANCSHFCIDRRDVGHQCF- 5152
T C A C DG S P SH C R QC
Sbjct: 2831 QTTNICVPRAFLCDGDNDCGDG-------------SDENPIYCASHTC---RSNEFQCLS 2874
Query: 5151 ---CAPGYILSENQKDC 5110
C P Y + + DC
Sbjct: 2875 PQRCIPSYWFCDGEADC 2891
Score = 48.9 bits (115), Expect = 0.002
Identities = 87/405 (21%), Positives = 133/405 (32%), Gaps = 35/405 (8%)
Frame = -1
Query: 1821 HQKNPCQSDY--------CPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQLREK 1666
H + C+++Y C C + D+ G C P F + C+ LR K
Sbjct: 3683 HTEFSCKTNYRCIPQWAVCNGFDDCRDNSDEQGC--ESVPCHPSGDFRCANHHCIPLRWK 3740
Query: 1665 DQEASQCGDYFCYNNAGCSPQKTCVCPPGFYGRQC--------EINECSETCWNGE---- 1522
CGD N C P++ +QC + N+C + +
Sbjct: 3741 CDGTDDCGDNSDEEN--CVPRECSESEFRCADQQCIPSRWVCDQENDCGDNSDERDCEMK 3798
Query: 1521 TCAVQEFGSTTNVVCHCPSNYT----QSSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSY 1354
TC + F T+ HC ++ C E C R T CP C+++
Sbjct: 3799 TCHPEHFQCTSG---HCVPKALACDGRADCLDASDESACPTRFPNGTY-CPAAMFECKNH 3854
Query: 1353 ----SFCECDKGWTGPHCRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQN 1186
SF CD C +D ++ CF+ E P RC +RC
Sbjct: 3855 VCIQSFWICDGE---NDCVDGSDEEIHL--CFN---IPCESPQRFRCD------NSRC-- 3898
Query: 1185 CVGHECLNGGFCSYANSNRSLPHCICPSGFTGDHCE--EYLCKDACPFGSKCTYDITKPM 1012
GH+ NG S+ HC P T C EY C + D
Sbjct: 3899 VYGHQLCNGVDDCGDGSDEKEEHCRKP---THKPCTDTEYKCSNGNCISQHYVCDNVNDC 3955
Query: 1011 DPITCSCEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPR----- 847
++ N + T IC++ +GG C C P F
Sbjct: 3956 GDLSDETGCNLGDNRTCAENICEQNCTQLSSGGFI---------CSCRPGFKPSTSDKNS 4006
Query: 846 CDVPVQCDDYCTNNSKCTITNGTHFECDCKPGFKGLRCEQETKCS 712
C +C+++ C + G+ +EC C GFK + +C+
Sbjct: 4007 CQDINECEEFGICPQSCRNSKGS-YECFCVDGFKSMSTHYGERCA 4050
Score = 47.8 bits (112), Expect = 0.004
Identities = 89/399 (22%), Positives = 133/399 (33%), Gaps = 36/399 (9%)
Frame = -1
Query: 1791 CPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGC 1612
C C+ D D+ G P C G F + C+ E C D G
Sbjct: 47 CDGTRDCLDDTDEIGC--PPRSCESGLFLCPAEGTCIPSSWVCDEDKDCSD-------GA 97
Query: 1611 SPQKTCVCPPGFYGRQCEINECSETCWNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNV 1432
Q+ C G C + TC NG+ C E+ + V CP + +C
Sbjct: 98 DEQQNCA------GTTCSAQQM--TCSNGQ-CIPSEY--RCDHVSDCPDGSDERNCHYPT 146
Query: 1431 CEGVCGPRGSC--------KTVPC--PKDEPHCR---SYSFCECDKG------WTGPH-- 1315
C+ + G+C + V C DE +C S EC G + H
Sbjct: 147 CDQLTCANGACYNTSQRCDQKVDCRDSSDEANCTTLCSQKEFECGSGECILRAYVCDHDN 206
Query: 1314 -CRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQNCVG-HECLNGGFCSYA 1141
C +D + C + C G + +C +G N+ C G +C + G
Sbjct: 207 DCEDNSDERNC-----NYDTCGGH-----QFTCSNGQCINQNWVCDGDDDCQDSGDEDGC 256
Query: 1140 NSNRSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCSCEQNAAAHNTD 961
SN+S C Y + ACP +C I K D + C + +N
Sbjct: 257 ESNQSHHRC-------------YPREWACPGSGRC-ISIDKVCDGVP-DCPEGDDENNVT 301
Query: 960 ---------CSPI-CQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYCT 811
CS + C+ Q + GG C PG+ + C C +
Sbjct: 302 SGRTCGMGVCSVLNCEYQCHQTPFGGECFCPPGH-----IINSNDSRTCIDFDDCQIWGI 356
Query: 810 NNSKCTITNGTHFECDCKPGF---KGLRCEQETKCSECS 703
+ KC G H +C C+ G+ +G C+ S S
Sbjct: 357 CDQKCENRQGRH-QCLCEEGYILERGQHCKSSDSFSAAS 394
Score = 47.8 bits (112), Expect = 0.004
Identities = 110/479 (22%), Positives = 152/479 (30%), Gaps = 44/479 (9%)
Frame = -1
Query: 1803 QSDYCPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCGDY---- 1636
QS C S C+ + D++ C PG+ F+ + +C+ K + CGDY
Sbjct: 3611 QSWQCDSVNDCLDNSDEDTSHCASRTCRPGQ-FKCNNGRCIPQSWKCDVDNDCGDYSDEP 3669
Query: 1635 -----------------FCYNNAGCSPQKTCVCPPGFYGRQCEINECSETCWNGETCAVQ 1507
C N C PQ VC GF C N + C E+
Sbjct: 3670 IDECTTAAYNCDNHTEFSCKTNYRCIPQ-WAVC-NGF--DDCRDNSDEQGC---ESVPCH 3722
Query: 1506 EFGSTTNVVCHC-PSNYT---QSSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSYSFCEC 1339
G HC P + C N E C PR ++ D+ S C+
Sbjct: 3723 PSGDFRCANHHCIPLRWKCDGTDDCGDNSDEENCVPRECSESEFRCADQQCIPSRWVCDQ 3782
Query: 1338 DKGWTGPHCRHKADAKVCY--------GHCFSGG-ACDGEGPLNLRCSCGDGLTGNRCQN 1186
+ + K C+ GHC ACDG R C D + C
Sbjct: 3783 ENDCGDNSDERDCEMKTCHPEHFQCTSGHCVPKALACDG------RADCLDASDESACPT 3836
Query: 1185 CVGHECLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLC--KDACPFGSKCTYDITKPM 1012
NG +C A + +C F ++C ++ C GS +
Sbjct: 3837 ----RFPNGTYCPAAMF--ECKNHVCIQSF-------WICDGENDCVDGSDEEIHL---C 3880
Query: 1011 DPITCSCEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPV 832
I C Q N+ C Q C+ C D + C P D
Sbjct: 3881 FNIPCESPQRFRCDNSRCVYGHQ----LCNGVDDCGDGSDEKEE-HCRKPTHKPCTDTEY 3935
Query: 831 QCDDYCTNNSKCTITNGTHFEC----DC--KPGFKGLRCEQETKCSECSNEAKCIKKPSG 670
+C +N C H+ C DC G C+E E C + SG
Sbjct: 3936 KC-----SNGNCI---SQHYVCDNVNDCGDLSDETGCNLGDNRTCAENICEQNCTQLSSG 3987
Query: 669 TVICQCPQGLGGEYCEKITATSCHQL-ECKNGGYCLKPDPSAN-RTSPTCLCSPGFKGL 499
IC C G +K SC + EC+ G C P N + S C C GFK +
Sbjct: 3988 GFICSCRPGFKPSTSDK---NSCQDINECEEFGIC--PQSCRNSKGSYECFCVDGFKSM 4041
Score = 40.8 bits (94), Expect = 0.45
Identities = 23/74 (31%), Positives = 32/74 (43%), Gaps = 1/74 (1%)
Frame = -1
Query: 600 HQLECKNGGY-CLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCLHDGNCTLDEYFEP 424
H + GGY C P S T T C + + C C+H GNC DE P
Sbjct: 4342 HLCLLRPGGYSCACPQGSDFVTGSTVQCDAASELPVTMPPPCR--CMHGGNCYFDENELP 4399
Query: 423 QCECYQAFIGDRCQ 382
+C+C + G+ C+
Sbjct: 4400 KCKCSSGYSGEYCE 4413
Score = 37.4 bits (85), Expect = 5.0
Identities = 23/77 (29%), Positives = 34/77 (43%), Gaps = 13/77 (16%)
Frame = -1
Query: 1242 PLNLRCSCGDG---LTGNRCQNCVGHE----------CLNGGFCSYANSNRSLPHCICPS 1102
P C+C G +TG+ Q E C++GG C + LP C C S
Sbjct: 4348 PGGYSCACPQGSDFVTGSTVQCDAASELPVTMPPPCRCMHGGNCYF--DENELPKCKCSS 4405
Query: 1101 GFTGDHCEEYLCKDACP 1051
G++G++CE L + P
Sbjct: 4406 GYSGEYCEVGLSRGIPP 4422
>gi|34854634|ref|XP_346657.1| hypothetical protein XP_346656 [Rattus
norvegicus]
Length = 2994
Score = 741 bits (1914), Expect = 0.0
Identities = 558/1821 (30%), Positives = 803/1821 (43%), Gaps = 149/1821 (8%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC---TCNEN-EFRCQ 6403
DE C+ CR F CGNG C+P C+ NDC + +DE+ C CN EF C
Sbjct: 1065 DELPTVCAFHTCRSTAFTCGNGRCVPYHYRCDYYNDCGDNSDEAGCLFRNCNSTTEFTCS 1124
Query: 6402 SGACIPSKARCNHMQDC--NDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKC 6229
+G CIP CN + +C ND SDE CP C C TT+ C+ ++ C
Sbjct: 1125 NGRCIPLSYVCNGINNCHDNDTSDEKNCPPHTCPP-------DFTKCQTTNICVPRAFLC 1177
Query: 6228 DGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCA 6049
DG NDC DGSDE + A +C + +F CL+ + C+P +W CDG+ DCA
Sbjct: 1178 DGDNDCGDGSDENPIYC----------ASHTCRSN-EFQCLSPQRCIPSYWFCDGEADCA 1226
Query: 6048 DGSDEKNC---DAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDE---HQCETE-CD 5890
DGSDE + C + +F C++ + CI CDG DC D DE H CE + C
Sbjct: 1227 DGSDEPDTCGHSVNTCRASQFQCDNGR-CISGNWVCDGDNDCGDMSDEDQRHHCELQNCS 1285
Query: 5889 SKGGNATFRCTN-----HRCIPMAWRCDGTDDCMDNAKSLGSDEV-DCAAGRTSFHVPSR 5728
S F C N RCIP W CDG DC D L + + C+AG S
Sbjct: 1286 S----TQFTCVNSRPPNRRCIPQYWVCDGDADCSDALDELQNCTMRTCSAGEFS------ 1335
Query: 5727 CADETCVVACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDA 5548
CA+ CV + CD DC D DE+ C+ C N++ C +G+CI +CD
Sbjct: 1336 CANGRCV----RQSFRCDRRNDCGDYSDERGCSY--PPCHANQFTCQNGRCIPRFFVCDE 1389
Query: 5547 SVDCVDGSDEWVEICSLSEPPRRGCP-SGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDE 5371
DC DGSDE +C EP CP + C NG C++ ++C+ DC DE
Sbjct: 1390 DNDCGDGSDEQEHLCHTPEPT---CPLHQFRC--DNGH--CIEMGRVCNHVDDCSDNSDE 1442
Query: 5370 QCDNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKAN--C 5197
+ S+ + CD NC CSC GY L DK++C+ C ++ C
Sbjct: 1443 KGCGINECLDSSISRCDH--NCTDTITSFYCSCLPGYKLMS-DKRSCVDIDECKESPQLC 1499
Query: 5196 SHFCIDRRDVG-HQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKAT 5020
S C VG + C CAPGYI + K CR+N IE ++ + ++ T DG + +
Sbjct: 1500 SQKC--ENVVGSYICKCAPGYIREPDGKSCRQNSNIEPYLIFSNRYYIRNLTTDGSSYSL 1557
Query: 5019 LLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMS-NQPNTYRVINSLPTKGIDGIA 4843
+L L N VALD+D +YW D K I M N+ N +IN + + +A
Sbjct: 1558 ILQGLGNVVALDFDRVEKRLYWIDA----EKQIIERMFLNKTNRETIINHRLRRA-ESLA 1612
Query: 4842 VDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTP-------LNDPRAIVLDPLQALVF 4684
VDW+ R +Y+ D D + V D+ GR +++ + PR IVL P + V+
Sbjct: 1613 VDWVSRKLYWLDAILDCLFVSDLEGRHRKMIAQHCVDANNTFCFEHPRGIVLHPQRGHVY 1672
Query: 4683 WTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYD 4504
W DWG A+IGR+ MDG+N+ VI+ + I WPNA+ +D LY+ DAH YI + +
Sbjct: 1673 WADWGVHAYIGRIGMDGTNKSVIISTK-IEWPNAITIDYTNDLLYWADAHLGYIEFSDLE 1731
Query: 4503 GSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGF 4324
G R V GS+ H FAL +FED V+W+DW+ T+E+ +K G+ R VL+ + ++P
Sbjct: 1732 GHHRHTVYDGSLPHPFALTIFEDTVFWTDWNTRTVEKGNKYDGSGRVVLV-NTTHKPFDI 1790
Query: 4323 KIVHPSLQSMGSLKTARHPC-SQPARCDNLCIPANTPDLTTSSDNFTCMCAQGFRS---- 4159
+ HP Q + +PC + C +LC+ + FTC C F++
Sbjct: 1791 HVYHPYRQPISD-----NPCGTNNGGCSHLCL------IKAGGRGFTCACPDDFQTVQLR 1839
Query: 4158 EGRSCVSECKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFV 3979
+ C+ C F+C KCI WW+ +CP C GQF
Sbjct: 1840 DRTLCMPMCSSTQFLCGNNEKCIPIWWKCDGQKDCSDGSDE----PDLCPHRFCRLGQFQ 1895
Query: 3978 CGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSV 3799
C C LC+ +DC+ G DE+ CE+ C +++C +K+ CIP +
Sbjct: 1896 C------RDGNCTSPQALCNARQDCADGSDEDRVLCEHHRCESNEWQCANKR-CIPQSWQ 1948
Query: 3798 CDKEKDCDDGSDE--LNCEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPD 3625
CD DC D SDE +C +C+P F C NG +CIP+ + CD ++DC + DEP
Sbjct: 1949 CDSVNDCLDNSDEDTSHCASRTCRPGQFKCNNG----RCIPQSWKCDVDNDCGDYSDEP- 2003
Query: 3624 SCFGIGECT--------HEQFQC-TSGKCIPKRRQCDGTLDCRDGSDEKGCKK------- 3493
I ECT H +F C T+ +CIP+ C+G DCRD SDE+GC+
Sbjct: 2004 ----IDECTTAAYNCDNHTEFSCKTNYRCIPQWAVCNGFDDCRDNSDEQGCESVPCHPSG 2059
Query: 3492 --ECAIVCDNSCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKENR----KC--GGFAC 3337
CA ++ C+ CDG C D SDE E CV ++ E E R +C + C
Sbjct: 2060 DFRCA---NHHCIPLRWKCDGTDDCGDNSDE--ENCVPRECSESEFRCADQQCIPSRWVC 2114
Query: 3336 DGIVDCEDGSDEKGCPDLECHLAS---------NKSLICDGTIDCSSGKDENNCHN---N 3193
D DC D SDE+ C CH K+L CDG DC DE+ C N
Sbjct: 2115 DQENDCGDNSDERDCEMKTCHPEHFQCTSGHCVPKALACDGRADCLDASDESACPTRFPN 2174
Query: 3192 GE---SNFFQCSMQT-IKEWQVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCL 3025
G + F+C I+ + +CDG DC DG DE +C + + CD+ + C+
Sbjct: 2175 GTYCPAAMFECKNHVCIQSFWICDGENDCVDGSDEEIHLCFNIPCESPQRFRCDNSR-CV 2233
Query: 3024 DVSTALCDGIRDCFDGSDENPIHC-----KDMCKGKYRCTNGRCI-------DVSARXXX 2881
LC+G+ DC DGSDE HC K +Y+C+NG CI +V+
Sbjct: 2234 -YGHQLCNGVDDCGDGSDEKEEHCRKPTHKPCTDTEYKCSNGNCISQHYVCDNVNDCGDL 2292
Query: 2880 XXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSA 2701
AE +C Q C + C C PG+ + D+N C+ +++
Sbjct: 2293 SDETGCNLGDNRTCAE----NICEQNCTQLSSGGFICSCRPGFKPSTLDKNSCQDINECE 2348
Query: 2700 EMFITNGNRLHLMSLENSQVSV-LRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSR 2524
E I S NS+ S V K G D L+ + +
Sbjct: 2349 EFGICP------QSCRNSKGSYECFCVDGFKSMSTHYGERCAADGSPPLLLLPENVRIRK 2402
Query: 2523 VDIRSKKWSDGLIGSWGEEESTAGLITYDFMHNN-----VYFT----------------- 2410
+ S+K+S+ L EEE I YD+ + VY+T
Sbjct: 2403 YNTSSEKFSEYL-----EEEEHIQTIDYDWDPEHIGLSVVYYTVLAQGSQFGAIKRAYIP 2457
Query: 2409 --ESSEQN---------------RGVLFD-----------RQANIYVAKAKDTSTRTLIV 2314
ES N G+ D + I VA + LI
Sbjct: 2458 NFESGSNNPIREVDLGLKYLMQPDGLAVDWVGRHIYWSDAKSQRIEVATLDGRYRKWLIT 2517
Query: 2313 NSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFE 2134
++AV+P L+FWT P+I SA ++G + LV N+
Sbjct: 2518 TQLDQPAAIAVNPKLGLMFWTDQGKQPKIESAWMNG-----------EHRSVLVSENLGW 2566
Query: 2133 PTSMVLDFSN-ERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT 1957
P + +D+ N +R+YW D + IE + +DG DRR + + P ++D+ +Y +
Sbjct: 2567 PNGLSIDYLNDDRVYWSDSKEDVIEAIKYDGTDRRLIINEAM--KPFSLDIFEDKLYWVA 2624
Query: 1956 RQ-GSIHRMHKFTGKTNKYVQKIREVSPRI-QIRVAHPAKHTVSHITHQKNPCQSDYCPS 1783
++ G + R +KF GK NK +K+ V+P + Q+R+ H ++ S NPC+ C
Sbjct: 2625 KEKGEVWRQNKF-GKENK--EKVLVVNPWLTQVRIFHQLRYNQS----VSNPCK-QVCSH 2676
Query: 1782 NTVCVPDQDKNGILIPKCLCGPGR-FFEVSTKKCMQLREKDQEASQCGDYFCYNNAGC-- 1612
+ P C C G F ST +C E + C + C
Sbjct: 2677 LCLLRPGG-------YSCACPQGSDFVTGSTVQCDAASE--LPVTMPPPCRCMHGGNCYF 2727
Query: 1611 --SPQKTCVCPPGFYGRQCEI 1555
+ C C G+ G CE+
Sbjct: 2728 DENELPKCKCSSGYSGEYCEV 2748
Score = 351 bits (901), Expect = 1e-94
Identities = 408/1743 (23%), Positives = 651/1743 (36%), Gaps = 102/1743 (5%)
Frame = -1
Query: 5256 LSPYD--KKTCLRSPSCPKANCSHFCIDRRDVGH-QCFCAPGYILSENQKDCRRNDTIEA 5086
LSP + CL+S CSHFC ++ +C CA G L + K C +
Sbjct: 671 LSPAELNNNPCLQS----NGGCSHFCFALPELPTPRCGCAFG-TLGNDGKSCATSQ---- 721
Query: 5085 EILMVYGHRLKLFTI-----DGHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHD--GNK 4927
E ++Y L ++ D ++S +ALDYD +++ +++T + G
Sbjct: 722 EDFLIYSLNNSLRSLHFDPRDHSLPFQVISVAGTAIALDYDRRNNRIFFTQKLNSLRGQI 781
Query: 4926 AGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILL 4747
+ ++ S + +++++ DGIA DW+ R IYY+D ++ I G ++
Sbjct: 782 SYVSLYSGSSSPTVLLSNIGVT--DGIAFDWINRRIYYSDFSNQTINSMAEDGSNRAVIA 839
Query: 4746 KGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDA 4567
+ ++ PRAIVLDP + ++WTDWG +A I R + G N +V + + ++ WPN LA+D
Sbjct: 840 R---VSKPRAIVLDPCRGYMYWTDWGTNAKIERATL-GGNFRVPIVNTSLVWPNGLALDL 895
Query: 4566 PAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVH 4387
LY+ DA I G+ R +V+ + H F L V+ Y+YW+D + I R +
Sbjct: 896 ETDLLYWADASLQKIERSTLTGTNREVVV-STAFHSFGLTVYGQYIYWTDLYTRKIYRAN 954
Query: 4386 KITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQP-----ARCDNLCIPAN 4222
K G++ + +P G V +KT R CS P C ++C P
Sbjct: 955 KYDGSDLVAMTTRLPTQPSGISTV---------VKTQRQQCSNPCDQFNGGCSHICAP-- 1003
Query: 4221 TPDLTTSSDNFTCMCAQG----FRSEGRSCV----SECKPNDFVCTKTYKCISSWWRXXX 4066
+ C C ++ + CV + C F C + CI+ W+
Sbjct: 1004 ------GPNGAECQCPHEGNWYLANDNKYCVVDTGTRCNQLQFTCLNGH-CINQDWKCDN 1056
Query: 4065 XXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDE 3886
+ VC C + F CG +C+ CD DC DE
Sbjct: 1057 DNDCGDGSDE---LPTVCAFHTCRSTAFTCG------NGRCVPYHYRCDYYNDCGDNSDE 1107
Query: 3885 EPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDC--DDGSDELNCEITSCKPDFFACF 3712
N T +F C + +CIPL+ VC+ +C +D SDE NC +C PDF C
Sbjct: 1108 AGCLFRNCNST-TEFTCSN-GRCIPLSYVCNGINNCHDNDTSDEKNCPPHTCPPDFTKC- 1164
Query: 3711 NGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTS-GKCIPKRRQCDGT 3535
+ C+P+ F CDG++DC +G DE C +FQC S +CIP CDG
Sbjct: 1165 --QTTNICVPRAFLCDGDNDCGDGSDENPIYCASHTCRSNEFQCLSPQRCIPSYWFCDGE 1222
Query: 3534 LDCRDGSDEK-------GCKKECAIVCDNS-CVHADDLCDGKKKCNDGSDEDE------E 3397
DC DGSDE + CDN C+ + +CDG C D SDED+ +
Sbjct: 1223 ADCADGSDEPDTCGHSVNTCRASQFQCDNGRCISGNWVCDGDNDCGDMSDEDQRHHCELQ 1282
Query: 3396 ACVIKQLL----EKENRKC--GGFACDGIVDCEDGSDE-KGCPDLECHLAS--------- 3265
C Q NR+C + CDG DC D DE + C C
Sbjct: 1283 NCSSTQFTCVNSRPPNRRCIPQYWVCDGDADCSDALDELQNCTMRTCSAGEFSCANGRCV 1342
Query: 3264 NKSLICDGTIDCSSGKDENNC-HNNGESNFFQC-SMQTIKEWQVCDGRWDCADGLDESPE 3091
+S CD DC DE C + +N F C + + I + VCD DC DG DE
Sbjct: 1343 RQSFRCDRRNDCGDYSDERGCSYPPCHANQFTCQNGRCIPRFFVCDEDNDCGDGSDEQEH 1402
Query: 3090 MCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKGKYRCTNGR 2911
+C + + C + D C+++ +C+ + DC D SDE + +
Sbjct: 1403 LCHTPEPTCPLHQFRCDNGHCIEMG-RVCNHVDDCSDNSDEKGCGINECLDSSISRCDHN 1461
Query: 2910 CIDVSARXXXXXXXXXXXXXXXXGA----ECHHF-GVCAQKCWMAFNHTARCHCAPGYAR 2746
C D EC +C+QKC + C CAPGY R
Sbjct: 1462 CTDTITSFYCSCLPGYKLMSDKRSCVDIDECKESPQLCSQKCENVVG-SYICKCAPGYIR 1520
Query: 2745 TKNDENECEPLSKSAEMFITNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVF 2566
+ D C + + E ++ NR ++ +L S +++ + + + +D
Sbjct: 1521 -EPDGKSCRQ-NSNIEPYLIFSNRYYIRNLTTDGSS-----YSLILQGLGNVVALDFDRV 1573
Query: 2565 RTTLMYTVGIGNSRVD--IRSKKWSDGLIGSWGEEESTAGLITYDFMHNNVYFTESSEQN 2392
L Y + ++ +K + +I A + D++ +Y+ ++
Sbjct: 1574 EKRL-YWIDAEKQIIERMFLNKTNRETII---NHRLRRAESLAVDWVSRKLYWLDAILDC 1629
Query: 2391 RGV--LFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILSA 2218
V L R + D + + G + + P + ++W I
Sbjct: 1630 LFVSDLEGRHRKMIAQHCVDANNTFCFEHPRG----IVLHPQRGHVYWADWGVHAYIGRI 1685
Query: 2217 NLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRD 2038
+DG ++ I P ++ +D++N+ LYW D IE +G
Sbjct: 1686 GMDG-----------TNKSVIISTKIEWPNAITIDYTNDLLYWADAHLGYIEFSDLEGHH 1734
Query: 2037 RRTVRKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGKTNKYVQKIREVSPRIQIR 1861
R TV L P + + ++ ++ + +K+ G V + I
Sbjct: 1735 RHTVYDGSL-PHPFALTIFEDTVFWTDWNTRTVEKGNKYDGSGR--VVLVNTTHKPFDIH 1791
Query: 1860 VAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCM 1681
V HP + +S NPC ++ + +C+ G C C P F + +
Sbjct: 1792 VYHPYRQPIS-----DNPCGTNNGGCSHLCLIKAGGRGF---TCAC-PDDF------QTV 1836
Query: 1680 QLREKDQEASQCG--DYFCYNNAGCSP-------QKTC--------VCPPGFYGRQCEIN 1552
QLR++ C + C NN C P QK C +CP F C +
Sbjct: 1837 QLRDRTLCMPMCSSTQFLCGNNEKCIPIWWKCDGQKDCSDGSDEPDLCPHRF----CRLG 1892
Query: 1551 ECSETCWNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDE 1372
+ C +G C + C S+ + C + CE C C
Sbjct: 1893 QFQ--CRDG-NCTSPQALCNARQDCADGSDEDRVLCEHHRCE---SNEWQCANKRCIPQS 1946
Query: 1371 PHCRSYSFCECDKGWTGPHCRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLTGNRC 1192
C S + C + HC + + C +G ++ CGD +
Sbjct: 1947 WQCDSVNDCLDNSDEDTSHCASRT-CRPGQFKCNNGRCIPQSWKCDVDNDCGD-YSDEPI 2004
Query: 1191 QNC--VGHECLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDITK 1018
C + C N S + R +P +GF D C + + C
Sbjct: 2005 DECTTAAYNCDNHTEFSCKTNYRCIPQWAVCNGF--DDCRDNSDEQGC------------ 2050
Query: 1017 PMDPITCSCEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKC-----KCLPRFAG 853
+ + C + N C P+ K G + P +C +C +
Sbjct: 2051 --ESVPCHPSGDFRCANHHCIPLRWKCDGTDDCGDNSDEENCVPRECSESEFRCADQQCI 2108
Query: 852 PR---CDVPVQC-DDYCTNNSKCTITNGTHFEC---DCKPGFKGLRCEQETKCSECSNEA 694
P CD C D+ + + + HF+C C P K L C+ C + S+E+
Sbjct: 2109 PSRWVCDQENDCGDNSDERDCEMKTCHPEHFQCTSGHCVP--KALACDGRADCLDASDES 2166
Query: 693 KC-IKKPSGTVICQCPQGLGGEYCEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCS 517
C + P+GT CP + ECKN +C
Sbjct: 2167 ACPTRFPNGT---YCPAAM---------------FECKNH-----------------VCI 2191
Query: 516 PGFKGLLCSSNACENFCLHDGNCTLDEYFEPQCECYQAFIGD--RCQYRIHQHAVIFSDD 343
F +C EN C+ + + F CE Q F D RC ++ H + D
Sbjct: 2192 QSF--WICDG---ENDCVDGSDEEIHLCFNIPCESPQRFRCDNSRC---VYGHQLCNGVD 2243
Query: 342 DSG 334
D G
Sbjct: 2244 DCG 2246
Score = 149 bits (377), Expect = 7e-34
Identities = 92/253 (36%), Positives = 121/253 (47%), Gaps = 10/253 (3%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC---TCNENEFRCQ 6403
D+ D + C R C F C + CIP + VC++ NDC + +DE +C TC+ F+C
Sbjct: 2083 DNSDEENCVPRECSESEFRCADQQCIPSRWVCDQENDCGDNSDERDCEMKTCHPEHFQCT 2142
Query: 6402 SGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDG 6223
SG C+P C+ DC DASDE CP R + + + C CI W CDG
Sbjct: 2143 SGHCVPKALACDGRADCLDASDESACPTRFPN--GTYCPAAMFEC-KNHVCIQSFWICDG 2199
Query: 6222 TNDCYDGSDEKD--CFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCA 6049
NDC DGSDE+ CF + P C++ +F C +R C+ H C+G DC
Sbjct: 2200 ENDCVDGSDEEIHLCF----------NIP--CESPQRFRCDNSR-CVYGHQLCNGVDDCG 2246
Query: 6048 DGSDEKNCDAKK-----CTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSK 5884
DGSDEK +K CT E+ C S+ CI CD DC D DE C +
Sbjct: 2247 DGSDEKEEHCRKPTHKPCTDTEYKC-SNGNCISQHYVCDNVNDCGDLSDETGC-----NL 2300
Query: 5883 GGNATFRCTNHRC 5845
G N T C + C
Sbjct: 2301 GDNRT--CAENIC 2311
Score = 140 bits (352), Expect = 5e-31
Identities = 106/380 (27%), Positives = 180/380 (46%), Gaps = 19/380 (5%)
Frame = -1
Query: 5226 RSPSCPKANCSHFCIDRRDVG--HQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLK 5053
R+P C A+CSH C+ + C C G+ LS++ +C R D + ++ V + +
Sbjct: 36 RNP-CASASCSHLCLLSAQAPRHYSCACPSGWNLSDDSVNCVRGD--QPFLMSVRDNIIF 92
Query: 5052 LFTIDGHAKAT----LLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYR 4885
++D K+ +S + +G +++D +YW + N I + +
Sbjct: 93 GISLDPEVKSNDAMVPISGIQHGYDVEFDDSEQFIYWVE-----NPGEIHRVKTDGSNRT 147
Query: 4884 VINSLPTKGID-GIAVDWLGRNIYYTDRNHDAIAVCDMRG--RFNRILLK--GTPLND-- 4726
V L G G+A+DW+ RNIYYT +I V ++G R+ + L+ GTPL
Sbjct: 148 VFAPLSLLGSSLGLALDWVSRNIYYTTPASRSIEVLTLKGDTRYGKTLIANDGTPLGVGF 207
Query: 4725 PRAIVLDPLQALVFW----TDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQ 4558
P I +DP + ++W TD G A I NMDG++ +++ ++ + +D Q
Sbjct: 208 PVGIAVDPARGKLYWSDHGTDSGVPAKIASANMDGTSLKILFTGN-LQHLEVVTLDIQEQ 266
Query: 4557 RLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKIT 4378
+LY+ R I N DG++R M+L + H + L V+ ++Y+SD IERV K +
Sbjct: 267 KLYWAVTSRGVIERGNVDGTER-MILVHHLAHPWGLVVYGSFLYYSDEQYEVIERVDKSS 325
Query: 4377 GTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDNLCIPANTPDLTTSS 4198
G N KV+++D G ++ H + ++ + P C +C+P
Sbjct: 326 G-NNKVVLRDNVPYLRGLRVYH----RRNAADSSNGCSNNPNACQQICLP-------VPG 373
Query: 4197 DNFTCMCAQGFR--SEGRSC 4144
F+C CA GF+ +GRSC
Sbjct: 374 GMFSCACASGFKLSPDGRSC 393
Score = 130 bits (327), Expect = 4e-28
Identities = 91/258 (35%), Positives = 120/258 (46%), Gaps = 18/258 (6%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADES---NC---TCNENEF 6412
D+ DT S CR F C NG CI VC+ NDC + +DE +C C+ +F
Sbjct: 1230 DEPDTCGHSVNTCRASQFQCDNGRCISGNWVCDGDNDCGDMSDEDQRHHCELQNCSSTQF 1289
Query: 6411 RCQSG-----ACIPSKARCNHMQDCNDASDEI-GCPFRNCSALNEFGMTGLINCATTSQC 6250
C + CIP C+ DC+DA DE+ C R CSA G +CA +C
Sbjct: 1290 TCVNSRPPNRRCIPQYWVCDGDADCSDALDELQNCTMRTCSA-------GEFSCA-NGRC 1341
Query: 6249 IHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQC 6070
+ S++CD NDC D SDE+ C S P C A QF C R C+P+ + C
Sbjct: 1342 VRQSFRCDRRNDCGDYSDERGC-----------SYP-PCHA-NQFTCQNGR-CIPRFFVC 1387
Query: 6069 DGQPDCADGSDEKN--CDAKK--CTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCE 5902
D DC DGSDE+ C + C +F C++ CI + + C+ DC D DE C
Sbjct: 1388 DEDNDCGDGSDEQEHLCHTPEPTCPLHQFRCDNG-HCIEMGRVCNHVDDCSDNSDEKGCG 1446
Query: 5901 -TEC-DSKGGNATFRCTN 5854
EC DS CT+
Sbjct: 1447 INECLDSSISRCDHNCTD 1464
Score = 112 bits (279), Expect = 2e-22
Identities = 97/376 (25%), Positives = 165/376 (43%), Gaps = 11/376 (2%)
Frame = -1
Query: 5232 CLRSPSCPKANCSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILM--VYGHR 5059
C +P+ C C+ C CA G+ LS + + C ++ ++ V G
Sbjct: 357 CSNNPNA----CQQICLPVPGGMFSCACASGFKLSPDGRSCSPYNSFMVVSMLPAVRGFS 412
Query: 5058 LKLFTIDGHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKA-GITSMSNQPNTYR- 4885
L+L + A + N + D DV + +YW D + + GI + + +
Sbjct: 413 LEL-SDHSEAMVPVAGQGRNVLHADVDVANGFIYWCDFSSSVRSSNGIRRIKPDGSNFTN 471
Query: 4884 -VINSLPTKGIDGIAVDWLGRNIYYTDR--NHDAIAVCDMRGRFNRILLKGTPLNDPRAI 4714
V + GI G+A+DW N+Y+T+ I V + + R+LLK ++ PR I
Sbjct: 472 VVTYGIGANGIRGVALDWAAGNLYFTNAFVYETLIEVLRINTTYRRVLLK-VSVDMPRHI 530
Query: 4713 VLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAH 4534
++DP +FW D+G I R +D +N V++ + + P LA+D +Y+ D
Sbjct: 531 IVDPKHRYLFWADYGQKPKIERSFLDCTNRTVLVSEGIVT-PRGLAMDHDTGYIYWVDDS 589
Query: 4533 RDYIASCNYDGSKRRMVLRGS-VRHIFALAVFEDYVYWSDWHNHTIERVHKITG-TNRKV 4360
D IA + DG + ++V GS + + VF + + W D + + + K G T+ V
Sbjct: 590 LDLIARIHLDGGESQVVRYGSRYPTPYGITVFGESIIWVDRNLKKVFQASKQPGNTDPPV 649
Query: 4359 LIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQP-ARCDNLCIPANTPDLTTSSDNFTC 4183
+I+DK I Q + + +PC Q C + C P+L T C
Sbjct: 650 VIRDKINLLRDVTIFDEHAQPLSPAELNNNPCLQSNGGCSHFCFA--LPELPTP----RC 703
Query: 4182 MCAQG-FRSEGRSCVS 4138
CA G ++G+SC +
Sbjct: 704 GCAFGTLGNDGKSCAT 719
Score = 99.0 bits (245), Expect = 1e-18
Identities = 74/248 (29%), Positives = 107/248 (42%), Gaps = 17/248 (6%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCT--------CNEN 6418
D+ D + C + C P +F C +G C+P+ C+ DC + +DES C C
Sbjct: 2122 DNSDERDCEMKTCHPEHFQCTSGHCVPKALACDGRADCLDASDESACPTRFPNGTYCPAA 2181
Query: 6417 EFRCQSGACIPSKARCNHMQDCNDASD-EIGCPFR-NCSALNEFGMTGLINCATTSQCIH 6244
F C++ CI S C+ DC D SD EI F C + F S+C++
Sbjct: 2182 MFECKNHVCIQSFWICDGENDCVDGSDEEIHLCFNIPCESPQRFR-------CDNSRCVY 2234
Query: 6243 PSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDG 6064
C+G +DC DGSDEK+ + C T++ C + C+ +H+ CD
Sbjct: 2235 GHQLCNGVDDCGDGSDEKEEHCR-------KPTHKPC-TDTEYKC-SNGNCISQHYVCDN 2285
Query: 6063 QPDCADGSDEKNCD-AKKCTSFEFSCESSKKCIPLEQK---CDGRRDC-PDGEDEHQCE- 5902
DC D SDE C+ T E CE + C L C R P D++ C+
Sbjct: 2286 VNDCGDLSDETGCNLGDNRTCAENICE--QNCTQLSSGGFICSCRPGFKPSTLDKNSCQD 2343
Query: 5901 -TECDSKG 5881
EC+ G
Sbjct: 2344 INECEEFG 2351
Score = 57.8 bits (138), Expect = 4e-06
Identities = 79/372 (21%), Positives = 132/372 (35%), Gaps = 5/372 (1%)
Frame = -1
Query: 2814 CAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQVS- 2638
C Q C C CA G+ + D C P + M ++ + SLE S S
Sbjct: 364 CQQICLPVPGGMFSCACASGF-KLSPDGRSCSPYNSF--MVVSMLPAVRGFSLELSDHSE 420
Query: 2637 VLRPVFNIKMNLIPGGIDFGYD-VFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEES 2461
+ PV N++ +D ++ +V N I+ + + ++G +
Sbjct: 421 AMVPVAGQGRNVLHADVDVANGFIYWCDFSSSVRSSNGIRRIKPDGSNFTNVVTYGIGAN 480
Query: 2460 TAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAV 2281
+ D+ N+YFT + F + I V + T R L+ S + V
Sbjct: 481 GIRGVALDWAAGNLYFTNA--------FVYETLIEVLRINTTYRRVLLKVSVDMPRHIIV 532
Query: 2280 DPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNE 2101
DP R +FW P+I + LD LV I P + +D
Sbjct: 533 DPKHRYLFWADYGQKPKIERSFLD-----------CTNRTVLVSEGIVTPRGLAMDHDTG 581
Query: 2100 RLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITRQ-GSIHRMHKF 1924
+YW+D I + DG + + VR TP + V G I + R + + K
Sbjct: 582 YIYWVDDSLDLIARIHLDGGESQVVRYGSRYPTPYGITVFGESIIWVDRNLKKVFQASKQ 641
Query: 1923 TGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPC--QSDYCPSNTVCVPDQDKN 1750
G T+ V +++ + + +S NPC + C +P+
Sbjct: 642 PGNTDPPVVIRDKINLLRDVTIFDEHAQPLSPAELNNNPCLQSNGGCSHFCFALPE---- 697
Query: 1749 GILIPKCLCGPG 1714
+ P+C C G
Sbjct: 698 -LPTPRCGCAFG 708
Score = 56.6 bits (135), Expect = 8e-06
Identities = 52/197 (26%), Positives = 68/197 (34%), Gaps = 7/197 (3%)
Frame = -1
Query: 5679 CDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASVDCVDGSDEWVEICS 5500
CD DC DG DE C+ + C +G+C+ CD DC D SDE C
Sbjct: 1054 CDNDNDCGDGSDELPTVCAFHTCRSTAFTCGNGRCVPYHYRCDYYNDCGDNSDE--AGCL 1111
Query: 5499 LSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCM-SGIDEQCDNPQGNCSSTRNSC 5323
R C S +NG C+ +C+G +C + ++ + P C C
Sbjct: 1112 F-----RNCNSTTEFTCSNGR--CIPLSYVCNGINNCHDNDTSDEKNCPPHTCPPDFTKC 1164
Query: 5322 DQTWNCQRHAGF--ESCSCDDGYHLSPYDKKTCLRSPSCPKANCSHFCIDRRDVGHQCF- 5152
T C A C DG S P SH C R QC
Sbjct: 1165 QTTNICVPRAFLCDGDNDCGDG-------------SDENPIYCASHTC---RSNEFQCLS 1208
Query: 5151 ---CAPGYILSENQKDC 5110
C P Y + + DC
Sbjct: 1209 PQRCIPSYWFCDGEADC 1225
Score = 48.9 bits (115), Expect = 0.002
Identities = 87/405 (21%), Positives = 133/405 (32%), Gaps = 35/405 (8%)
Frame = -1
Query: 1821 HQKNPCQSDY--------CPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQLREK 1666
H + C+++Y C C + D+ G C P F + C+ LR K
Sbjct: 2017 HTEFSCKTNYRCIPQWAVCNGFDDCRDNSDEQGC--ESVPCHPSGDFRCANHHCIPLRWK 2074
Query: 1665 DQEASQCGDYFCYNNAGCSPQKTCVCPPGFYGRQC--------EINECSETCWNGE---- 1522
CGD N C P++ +QC + N+C + +
Sbjct: 2075 CDGTDDCGDNSDEEN--CVPRECSESEFRCADQQCIPSRWVCDQENDCGDNSDERDCEMK 2132
Query: 1521 TCAVQEFGSTTNVVCHCPSNYT----QSSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSY 1354
TC + F T+ HC ++ C E C R T CP C+++
Sbjct: 2133 TCHPEHFQCTSG---HCVPKALACDGRADCLDASDESACPTRFPNGTY-CPAAMFECKNH 2188
Query: 1353 ----SFCECDKGWTGPHCRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQN 1186
SF CD C +D ++ CF+ E P RC +RC
Sbjct: 2189 VCIQSFWICDGE---NDCVDGSDEEIHL--CFN---IPCESPQRFRCD------NSRC-- 2232
Query: 1185 CVGHECLNGGFCSYANSNRSLPHCICPSGFTGDHCE--EYLCKDACPFGSKCTYDITKPM 1012
GH+ NG S+ HC P T C EY C + D
Sbjct: 2233 VYGHQLCNGVDDCGDGSDEKEEHCRKP---THKPCTDTEYKCSNGNCISQHYVCDNVNDC 2289
Query: 1011 DPITCSCEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPR----- 847
++ N + T IC++ +GG C C P F
Sbjct: 2290 GDLSDETGCNLGDNRTCAENICEQNCTQLSSGGFI---------CSCRPGFKPSTLDKNS 2340
Query: 846 CDVPVQCDDYCTNNSKCTITNGTHFECDCKPGFKGLRCEQETKCS 712
C +C+++ C + G+ +EC C GFK + +C+
Sbjct: 2341 CQDINECEEFGICPQSCRNSKGS-YECFCVDGFKSMSTHYGERCA 2384
Score = 47.8 bits (112), Expect = 0.004
Identities = 110/479 (22%), Positives = 152/479 (30%), Gaps = 44/479 (9%)
Frame = -1
Query: 1803 QSDYCPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCGDY---- 1636
QS C S C+ + D++ C PG+ F+ + +C+ K + CGDY
Sbjct: 1945 QSWQCDSVNDCLDNSDEDTSHCASRTCRPGQ-FKCNNGRCIPQSWKCDVDNDCGDYSDEP 2003
Query: 1635 -----------------FCYNNAGCSPQKTCVCPPGFYGRQCEINECSETCWNGETCAVQ 1507
C N C PQ VC GF C N + C E+
Sbjct: 2004 IDECTTAAYNCDNHTEFSCKTNYRCIPQ-WAVC-NGF--DDCRDNSDEQGC---ESVPCH 2056
Query: 1506 EFGSTTNVVCHC-PSNYT---QSSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSYSFCEC 1339
G HC P + C N E C PR ++ D+ S C+
Sbjct: 2057 PSGDFRCANHHCIPLRWKCDGTDDCGDNSDEENCVPRECSESEFRCADQQCIPSRWVCDQ 2116
Query: 1338 DKGWTGPHCRHKADAKVCY--------GHCFSGG-ACDGEGPLNLRCSCGDGLTGNRCQN 1186
+ + K C+ GHC ACDG R C D + C
Sbjct: 2117 ENDCGDNSDERDCEMKTCHPEHFQCTSGHCVPKALACDG------RADCLDASDESACPT 2170
Query: 1185 CVGHECLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLC--KDACPFGSKCTYDITKPM 1012
NG +C A + +C F ++C ++ C GS +
Sbjct: 2171 ----RFPNGTYCPAAMF--ECKNHVCIQSF-------WICDGENDCVDGSDEEIHL---C 2214
Query: 1011 DPITCSCEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPV 832
I C Q N+ C Q C+ C D + C P D
Sbjct: 2215 FNIPCESPQRFRCDNSRCVYGHQ----LCNGVDDCGDGSDEKEE-HCRKPTHKPCTDTEY 2269
Query: 831 QCDDYCTNNSKCTITNGTHFEC----DC--KPGFKGLRCEQETKCSECSNEAKCIKKPSG 670
+C +N C H+ C DC G C+E E C + SG
Sbjct: 2270 KC-----SNGNCI---SQHYVCDNVNDCGDLSDETGCNLGDNRTCAENICEQNCTQLSSG 2321
Query: 669 TVICQCPQGLGGEYCEKITATSCHQL-ECKNGGYCLKPDPSAN-RTSPTCLCSPGFKGL 499
IC C G +K SC + EC+ G C P N + S C C GFK +
Sbjct: 2322 GFICSCRPGFKPSTLDK---NSCQDINECEEFGIC--PQSCRNSKGSYECFCVDGFKSM 2375
Score = 40.8 bits (94), Expect = 0.45
Identities = 23/74 (31%), Positives = 32/74 (43%), Gaps = 1/74 (1%)
Frame = -1
Query: 600 HQLECKNGGY-CLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCLHDGNCTLDEYFEP 424
H + GGY C P S T T C + + C C+H GNC DE P
Sbjct: 2676 HLCLLRPGGYSCACPQGSDFVTGSTVQCDAASELPVTMPPPCR--CMHGGNCYFDENELP 2733
Query: 423 QCECYQAFIGDRCQ 382
+C+C + G+ C+
Sbjct: 2734 KCKCSSGYSGEYCE 2747
Score = 37.4 bits (85), Expect = 5.0
Identities = 23/77 (29%), Positives = 34/77 (43%), Gaps = 13/77 (16%)
Frame = -1
Query: 1242 PLNLRCSCGDG---LTGNRCQNCVGHE----------CLNGGFCSYANSNRSLPHCICPS 1102
P C+C G +TG+ Q E C++GG C + LP C C S
Sbjct: 2682 PGGYSCACPQGSDFVTGSTVQCDAASELPVTMPPPCRCMHGGNCYF--DENELPKCKCSS 2739
Query: 1101 GFTGDHCEEYLCKDACP 1051
G++G++CE L + P
Sbjct: 2740 GYSGEYCEVGLSRGIPP 2756
>gi|38074796|ref|XP_130308.2| similar to low density lipoprotein
receptor-related protein 2; glycoprotein 330; low density
lipoprotein-related protein 2; megalin [Mus musculus]
Length = 3312
Score = 730 bits (1885), Expect = 0.0
Identities = 549/1817 (30%), Positives = 799/1817 (43%), Gaps = 145/1817 (7%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC---TCNEN-EFRCQ 6403
DE C+ CR F C NG C+P C+ NDC + +DE+ C +CN EF C
Sbjct: 1383 DELPTVCAFHTCRSTAFTCANGRCVPYHYRCDFYNDCGDNSDEAGCLFRSCNSTTEFTCS 1442
Query: 6402 SGACIPSKARCNHMQDC--NDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKC 6229
+G CIP CN + +C ND SDE CP C C TT+ C+ ++ C
Sbjct: 1443 NGRCIPLSYVCNGINNCHDNDTSDEKNCPPITCQP-------DFAKCQTTNICVPRAFLC 1495
Query: 6228 DGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCA 6049
DG NDC DGSDE + A +C + +F C++ C+P +W CDG+ DC
Sbjct: 1496 DGDNDCGDGSDENPIYC----------ASHTCRSN-EFQCVSPHRCIPSYWFCDGEADCV 1544
Query: 6048 DGSDEKNC---DAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDE---HQCETE-CD 5890
D SDE + C++ +F C++ + CI CDG DC D DE H CE + C
Sbjct: 1545 DSSDEPDTCGHSLNSCSANQFHCDNGR-CISSSWVCDGDNDCGDMSDEDQRHHCELQNCS 1603
Query: 5889 SKGGNA-TFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVD-CAAGRTSFHVPSRCADE 5716
S R N RCIP W CDG DC D L + + C+ G S CA+
Sbjct: 1604 STEFTCINSRPPNRRCIPQHWVCDGDADCADALDELQNCTMRACSTGEFS------CANG 1657
Query: 5715 TCVVACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASVDC 5536
C+ + CD DC D DE+ C+ C+ +++ C +GQCI +CD DC
Sbjct: 1658 RCI----RQSFRCDRRNDCGDYSDERGCSY--PPCRDDQFTCQNGQCITKLYVCDEDNDC 1711
Query: 5535 VDGSDEWVEICSLSEPPRRGCPSG-WSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDN 5359
DGSDE +C EP CP + C NG C++ +C+ DC DE+
Sbjct: 1712 GDGSDEQEHLCHTPEPT---CPPHQFRC--DNGH--CIEMGTVCNHVDDCSDNSDEKGCG 1764
Query: 5358 PQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKAN--CSHFC 5185
S+ + CD NC CSC GY L DK+TC+ C + CS C
Sbjct: 1765 INECQDSSISHCDH--NCTDTITSFYCSCLPGYKLMS-DKRTCVDIDECKETPQLCSQKC 1821
Query: 5184 IDRRDVG-HQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSN 5008
+G + C CAPGYI + K CR+N IE ++ + ++ TIDG + + +L
Sbjct: 1822 --ENVIGSYICKCAPGYIREPDGKSCRQNSNIEPYLVFSNRYYIRNLTIDGTSYSLILQG 1879
Query: 5007 LTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLG 4828
L N VALD+D + +YW D K I M I S + + +AVDW+
Sbjct: 1880 LGNVVALDFDRVEERLYWIDA----EKQIIERMFLNKTNQETIISHRLRRAESLAVDWVS 1935
Query: 4827 RNIYYTDRNHDAIAVCDMRGRFNRILLKGTP-------LNDPRAIVLDPLQALVFWTDWG 4669
R +Y+ D D + V D+ GR ++L + +PR IVL P + V+W DWG
Sbjct: 1936 RKLYWLDAILDCLFVSDLEGRQRKMLAQHCVDANNTFCFENPRGIVLHPQRGYVYWADWG 1995
Query: 4668 ASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRR 4489
A+I R+ MDG+N+ VI+ + I WPNA+ +D LY+ DAH YI + +G R
Sbjct: 1996 DHAYIARIGMDGTNKTVIISTK-IEWPNAITIDYTNDLLYWADAHLGYIEFSDLEGHHRH 2054
Query: 4488 MVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHP 4309
V G++ H FAL +FED V+W+DW+ T+E+ +K G+ R VL+ + ++P ++HP
Sbjct: 2055 TVYDGTLPHPFALTIFEDTVFWTDWNTRTVEKGNKYDGSGRVVLV-NTTHKPFDIHVLHP 2113
Query: 4308 SLQSMGSLKTARHPC-SQPARCDNLCIPANTPDLTTSSDNFTCMCAQGFRS----EGRSC 4144
Q + S +PC + C +LC+ + FTC C F++ + C
Sbjct: 2114 YRQPIMS-----NPCATNNGGCSHLCL------IKAGGRGFTCECPDDFQTVQLRDRTLC 2162
Query: 4143 VSECKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTA 3964
+ C F+C KCI WW+ +CP C GQF C
Sbjct: 2163 MPMCSSTQFLCGNNEKCIPIWWKCDGQKDCSDGSDE----SDLCPHRFCRLGQFQC---- 2214
Query: 3963 QNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEK 3784
C LC+ +DC+ G DE+ CE+ C +++C + K+CIP CD
Sbjct: 2215 --RDGNCTSPQALCNARQDCADGSDEDRVLCEHHRCEANEWQCAN-KRCIPEYWQCDSVD 2271
Query: 3783 DCDDGSDE--LNCEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGI 3610
DC D SDE +C +C+P F C NG +CIP+ + CD ++DC + DEP I
Sbjct: 2272 DCLDNSDEDPSHCASRTCRPGQFKCNNG----RCIPQSWKCDVDNDCGDYSDEP-----I 2322
Query: 3609 GEC--------THEQFQC-TSGKCIPKRRQCDGTLDCRDGSDEKGCKKECAIVC------ 3475
EC H +F C T+ +CIP+ C+G DCRD SDE+GC+ ++ C
Sbjct: 2323 HECMTAAYNCDNHTEFSCKTNYRCIPQWAVCNGFDDCRDNSDEQGCE---SVPCHPSGDF 2379
Query: 3474 ---DNSCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKE----NRKC--GGFACDGIVD 3322
++ C+ CDG C D S DEE+CV ++ E E +++C + CD D
Sbjct: 2380 RCGNHHCIPLRWKCDGIDDCGDNS--DEESCVPRECTESEFRCADQQCIPSRWVCDQEND 2437
Query: 3321 CEDGSDEKGCPDLECH---------LASNKSLICDGTIDCSSGKDENNCHN---NG---E 3187
C D SDE+ C CH K+L CDG DC DE+ C NG
Sbjct: 2438 CGDNSDERDCEMKTCHPEHFQCTSGHCVPKALACDGRADCLDASDESACPTRFPNGTYCP 2497
Query: 3186 SNFFQCSMQT-IKEWQVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCLDVSTA 3010
+ F+C I+ + +CDG DC DG DE +C + + CD+ + C+
Sbjct: 2498 AAMFECKNHVCIQSFWICDGENDCVDGSDEEIHLCFNVPCESPQRFRCDNSR-CI-YGHQ 2555
Query: 3009 LCDGIRDCFDGSDENPIHC-----KDMCKGKYRCTNGRCI-------DVSARXXXXXXXX 2866
LC+G+ DC DGSDE HC K +Y+C+NG C+ +V
Sbjct: 2556 LCNGVDDCGDGSDEKEEHCRKPTHKPCTDTEYKCSNGNCVSQHYVCDNVDDCGDLSDETG 2615
Query: 2865 XXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFIT 2686
AE +C Q C N C C PG+ + D+N C+ +++ E I
Sbjct: 2616 CNLGENRTCAE----KICEQNCTQLSNGGFICSCRPGFKPSTLDKNSCQDINECEEFGIC 2671
Query: 2685 NGNRLHLMSLENSQVSV-LRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRS 2509
S NS+ S V K G D L+ + + +I S
Sbjct: 2672 P------QSCRNSKGSYECFCVDGFKSMSTHYGERCAADGSPPLLLLPENVRIRKYNISS 2725
Query: 2508 KKWSDGLIGSWGEEESTAGLITYDFMHNN-----VYFTESSE------------------ 2398
+K+S+ L EEE I YD+ VY+T S+
Sbjct: 2726 EKFSEYL-----EEEEHIQAIDYDWDPEGIGLSVVYYTVLSQGSQFGAIKRAYLPDFESG 2780
Query: 2397 ----------------QNRGVLFD-----------RQANIYVAKAKDTSTRTLIVNSTGT 2299
Q G+ D + I VA + LI
Sbjct: 2781 SNNPVREVDLGLKYLMQPDGLAVDWVGRHIYWSDAKSQRIEVATLDGRYRKWLITTQLDQ 2840
Query: 2298 INSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMV 2119
++AV+P L+FWT P+I SA ++G + L N+ P +
Sbjct: 2841 PAAIAVNPKLGLMFWTDQGKQPKIESAWMNG-----------EHRSVLASANLGWPNGLS 2889
Query: 2118 LDFSN-ERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITRQ-GS 1945
+D+ N +R+YW D + IE++ +DG DRR + + P ++D+ +Y + ++ G
Sbjct: 2890 IDYLNGDRIYWSDSKEDVIESIKYDGTDRRLIINDAM--KPFSLDIFEDQLYWVAKEKGE 2947
Query: 1944 IHRMHKFTGKTNKYVQKIREVSPRI-QIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCV 1768
+ R +KF GK NK +K+ V+P + Q+R+ H ++ S NPC+ C +
Sbjct: 2948 VWRQNKF-GKGNK--EKLLVVNPWLTQVRIFHQLRYNQS----VSNPCK-QVCSHLCLLR 2999
Query: 1767 PDQDKNGILIPKCLCGPGR-FFEVSTKKCMQLREKD-QEASQCGDYFCYNNAGC----SP 1606
P C C G F ST +C E S C C + C +
Sbjct: 3000 PGG-------YSCACPQGSDFVTGSTVECDAASELPITMPSPCR---CMHGGSCYFDEND 3049
Query: 1605 QKTCVCPPGFYGRQCEI 1555
C C G+ G CEI
Sbjct: 3050 LPKCKCSSGYSGEYCEI 3066
Score = 355 bits (912), Expect = 6e-96
Identities = 418/1749 (23%), Positives = 662/1749 (36%), Gaps = 107/1749 (6%)
Frame = -1
Query: 5259 HLSPYDKKTCLRSPSCPKAN--CSHFCIDRRDVGH-QCFCAPGYILSENQKDCRRNDTIE 5089
H+ P +P C ++N CSHFC ++ +C CA G L ++ K+C +
Sbjct: 985 HVQPLSPAELNNNP-CLQSNGGCSHFCFALPELPTPKCGCAFG-TLEDDGKNCATS---- 1038
Query: 5088 AEILMVYGHRLKLFTI-----DGHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKA 4924
E ++Y L ++ D + +S +ALDYD +++ +++T +
Sbjct: 1039 REDFLIYSLNNSLRSLHFDPQDHNLPFQAISVEGMAIALDYDRRNNRIFFTQKLNP---- 1094
Query: 4923 GITSMSNQPNTYRVINS----LPTKGI-DGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFN 4759
I + N Y +S L G+ DGIA DW+ R IYY+D ++ I G
Sbjct: 1095 -IRGQISYVNLYSGASSPTILLSNIGVTDGIAFDWINRRIYYSDFSNQTINSMAEDGSNR 1153
Query: 4758 RILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNAL 4579
++ + ++ PRAIVLDP + ++WTDWG +A I R + G N +V + + ++ WPN L
Sbjct: 1154 AVIAR---VSKPRAIVLDPCRGYMYWTDWGTNAKIERATL-GGNFRVPIVNTSLVWPNGL 1209
Query: 4578 AVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTI 4399
+D LY+ DA I GS R +V+ + H F L V+ Y+YW+D++ I
Sbjct: 1210 TLDLETDLLYWADASLQKIERSTLTGSNREVVI-STAFHSFGLTVYGQYIYWTDFYTKKI 1268
Query: 4398 ERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQP-----ARCDNLC 4234
R +K G++ + +P G V +KT + CS P C ++C
Sbjct: 1269 YRANKYDGSDLIAMTTRLPTQPSGISTV---------VKTQQQQCSNPCDQFNGGCSHIC 1319
Query: 4233 IPANTPDLTTSSDNFTCMCAQG----FRSEGRSCV----SECKPNDFVCTKTYKCISSWW 4078
P + C C ++ + CV + C F C +CIS W
Sbjct: 1320 AP--------GPNGAECQCPHEGSWYLANDNKYCVVDTGARCNQFQFTCLNG-RCISQDW 1370
Query: 4077 RXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSG 3898
+ + VC C + F C A +C+ CD DC
Sbjct: 1371 KCDNDNDCGDGSDE---LPTVCAFHTCRSTAFTC------ANGRCVPYHYRCDFYNDC-- 1419
Query: 3897 GDDEEPAFCENFEC-TEAQFKCGDKKKCIPLTSVCDKEKDC--DDGSDELNCEITSCKPD 3727
GD+ + A C C + +F C + +CIPL+ VC+ +C +D SDE NC +C+PD
Sbjct: 1420 GDNSDEAGCLFRSCNSTTEFTCSN-GRCIPLSYVCNGINNCHDNDTSDEKNCPPITCQPD 1478
Query: 3726 FFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTS-GKCIPKRR 3550
F C + C+P+ F CDG++DC +G DE C +FQC S +CIP
Sbjct: 1479 FAKC---QTTNICVPRAFLCDGDNDCGDGSDENPIYCASHTCRSNEFQCVSPHRCIPSYW 1535
Query: 3549 QCDGTLDCRDGSDE--------KGCKKECAIVCDNS-CVHADDLCDGKKKCNDGSDEDE- 3400
CDG DC D SDE C CDN C+ + +CDG C D SDED+
Sbjct: 1536 FCDGEADCVDSSDEPDTCGHSLNSCSAN-QFHCDNGRCISSSWVCDGDNDCGDMSDEDQR 1594
Query: 3399 EACVIKQLLEKE---------NRKC--GGFACDGIVDCEDGSDE------KGCPDLECHL 3271
C ++ E NR+C + CDG DC D DE + C E
Sbjct: 1595 HHCELQNCSSTEFTCINSRPPNRRCIPQHWVCDGDADCADALDELQNCTMRACSTGEFSC 1654
Query: 3270 ASNK----SLICDGTIDCSSGKDENNC-HNNGESNFFQC-SMQTIKEWQVCDGRWDCADG 3109
A+ + S CD DC DE C + + F C + Q I + VCD DC DG
Sbjct: 1655 ANGRCIRQSFRCDRRNDCGDYSDERGCSYPPCRDDQFTCQNGQCITKLYVCDEDNDCGDG 1714
Query: 3108 LDESPEMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKGKY 2929
DE +C + + C + D C+++ T +C+ + DC D SDE +
Sbjct: 1715 SDEQEHLCHTPEPTCPPHQFRCDNGHCIEMGT-VCNHVDDCSDNSDEKGCGINECQDSSI 1773
Query: 2928 RCTNGRCIDVSARXXXXXXXXXXXXXXXXGA----ECHHF-GVCAQKCWMAFNHTARCHC 2764
+ C D EC +C+QKC + C C
Sbjct: 1774 SHCDHNCTDTITSFYCSCLPGYKLMSDKRTCVDIDECKETPQLCSQKCENVIG-SYICKC 1832
Query: 2763 APGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGID 2584
APGY R + D C + + E ++ NR ++ +L S +++ + + +
Sbjct: 1833 APGYIR-EPDGKSCRQ-NSNIEPYLVFSNRYYIRNLTIDGTS-----YSLILQGLGNVVA 1885
Query: 2583 FGYDVFRTTLMYTVGIGNSRVD--IRSKKWSDGLIGSWGEEESTAGLITYDFMHNNVYFT 2410
+D L Y + ++ +K + +I A + D++ +Y+
Sbjct: 1886 LDFDRVEERL-YWIDAEKQIIERMFLNKTNQETII---SHRLRRAESLAVDWVSRKLYWL 1941
Query: 2409 ESSEQNRGV--LFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTSAPV 2236
++ V L RQ + D + N G + + P + ++W
Sbjct: 1942 DAILDCLFVSDLEGRQRKMLAQHCVDANNTFCFENPRG----IVLHPQRGYVYWADWGDH 1997
Query: 2235 PRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETV 2056
I +DG KT ++ I P ++ +D++N+ LYW D IE
Sbjct: 1998 AYIARIGMDGTN-----KT------VIISTKIEWPNAITIDYTNDLLYWADAHLGYIEFS 2046
Query: 2055 SFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGKTNKYVQKIREVS 1879
+G R TV L P + + ++ ++ + +K+ G V +
Sbjct: 2047 DLEGHHRHTVYDGTL-PHPFALTIFEDTVFWTDWNTRTVEKGNKYDGSGR--VVLVNTTH 2103
Query: 1878 PRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLCGPGRFFEV 1699
I V HP + + NPC ++ + +C+ G C C P F
Sbjct: 2104 KPFDIHVLHPYRQPI-----MSNPCATNNGGCSHLCLIKAGGRGF---TCEC-PDDF--- 2151
Query: 1698 STKKCMQLREKDQEASQCG--DYFCYNNAGCSP-------QKTC--------VCPPGFYG 1570
+ +QLR++ C + C NN C P QK C +CP F
Sbjct: 2152 ---QTVQLRDRTLCMPMCSSTQFLCGNNEKCIPIWWKCDGQKDCSDGSDESDLCPHRF-- 2206
Query: 1569 RQCEINECSETCWNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTV 1390
C + + C +G C + C S+ + C + CE C
Sbjct: 2207 --CRLGQFQ--CRDG-NCTSPQALCNARQDCADGSDEDRVLCEHHRCE---ANEWQCANK 2258
Query: 1389 PCPKDEPHCRSYSFCECDKGWTGPHCRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDG 1210
C + C S C + HC + + C +G ++ CGD
Sbjct: 2259 RCIPEYWQCDSVDDCLDNSDEDPSHCASRT-CRPGQFKCNNGRCIPQSWKCDVDNDCGD- 2316
Query: 1209 LTGNRCQNCV--GHECLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDACPFGSKC 1036
+ C+ + C N S + R +P +GF D C + + C
Sbjct: 2317 YSDEPIHECMTAAYNCDNHTEFSCKTNYRCIPQWAVCNGF--DDCRDNSDEQGC------ 2368
Query: 1035 TYDITKPMDPITCSCEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKC-----KC 871
+ + C + N C P+ K G + P +C +C
Sbjct: 2369 --------ESVPCHPSGDFRCGNHHCIPLRWKCDGIDDCGDNSDEESCVPRECTESEFRC 2420
Query: 870 LPRFAGPR---CDVPVQC-DDYCTNNSKCTITNGTHFEC---DCKPGFKGLRCEQETKCS 712
+ P CD C D+ + + + HF+C C P K L C+ C
Sbjct: 2421 ADQQCIPSRWVCDQENDCGDNSDERDCEMKTCHPEHFQCTSGHCVP--KALACDGRADCL 2478
Query: 711 ECSNEAKC-IKKPSGTVICQCPQGLGGEYCEKITATSCHQLECKNGGYCLKPDPSANRTS 535
+ S+E+ C + P+GT CP + ECKN
Sbjct: 2479 DASDESACPTRFPNGT---YCPAAM---------------FECKNH-------------- 2506
Query: 534 PTCLCSPGFKGLLCSSNACENFCLHDGNCTLDEYFEPQCECYQAFIGD--RCQYRIHQHA 361
+C F +C EN C+ + + F CE Q F D RC I+ H
Sbjct: 2507 ---VCIQSF--WICDG---ENDCVDGSDEEIHLCFNVPCESPQRFRCDNSRC---IYGHQ 2555
Query: 360 VIFSDDDSG 334
+ DD G
Sbjct: 2556 LCNGVDDCG 2564
Score = 191 bits (485), Expect = 2e-46
Identities = 129/421 (30%), Positives = 210/421 (49%), Gaps = 11/421 (2%)
Frame = -1
Query: 5355 QGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKAN-CSHFCID 5179
Q +C C T C + +C C GY L+ D KTC C CS C++
Sbjct: 3 QDSCLHFNGGC--THRCIQGPFGATCVCPIGYQLAN-DTKTCEDVNECDIPGFCSQHCVN 59
Query: 5178 RRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLF----TIDGHAKATLLS 5011
R +C C P Y L + + C+ T +L+V R K+ T H +L+
Sbjct: 60 MRG-SFRCACDPEYTLESDGRTCKV--TASENLLLVVASRDKIIMDNITAHTHNIYSLVQ 116
Query: 5010 NLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWL 4831
+++ VALD+D + V+W+D+ + + +++ RV++ + IAVDW+
Sbjct: 117 DVSFVVALDFDSVTGRVFWSDLLEGKTWSAFQNGTDK----RVVHDSGLSLTEMIAVDWI 172
Query: 4830 GRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQA--LVFWTDWGASAH 4657
GRNIY+TD + I V + G +L+ + PR + LDP ++FW+DWG
Sbjct: 173 GRNIYWTDYTLETIEVSKIDGSHRTVLISKN-VTKPRGLALDPRMGDNVMFWSDWGHHPR 231
Query: 4656 IGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLR 4477
I R +MDG+ VI+Q++ I WP L++D P + +YF DA+ DYI C+YDG RR V+
Sbjct: 232 IERASMDGTMRTVIVQEK-IYWPCGLSIDYPNRLIYFMDAYLDYIEFCDYDGQNRRQVIA 290
Query: 4476 GS--VRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSL 4303
+ H AL +FED V+W+D H + + +K G N+ V++ +P+G +HPS
Sbjct: 291 SDLVLHHPHALTLFEDSVFWTDRGTHQVMQANKWHGRNQSVVMYSVP-QPLGIIAIHPSR 349
Query: 4302 QSMGSLKTARHPCSQPARCDNLCIPANTPDLTTSSDNFTCMCAQGFR--SEGRSCVSECK 4129
Q ++ +PC+ A C +LC+ + +++C C G+ + +CV +
Sbjct: 350 Q-----PSSPNPCAS-ATCSHLCLLS-----AQEPRHYSCACPSGWNLSDDSVNCVRGDQ 398
Query: 4128 P 4126
P
Sbjct: 399 P 399
Score = 148 bits (374), Expect = 2e-33
Identities = 86/233 (36%), Positives = 114/233 (48%), Gaps = 10/233 (4%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC---TCNENEFRCQ 6403
D+ D + C R C F C + CIP + VC++ NDC + +DE +C TC+ F+C
Sbjct: 2401 DNSDEESCVPRECTESEFRCADQQCIPSRWVCDQENDCGDNSDERDCEMKTCHPEHFQCT 2460
Query: 6402 SGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDG 6223
SG C+P C+ DC DASDE CP R + + + C CI W CDG
Sbjct: 2461 SGHCVPKALACDGRADCLDASDESACPTRFPN--GTYCPAAMFEC-KNHVCIQSFWICDG 2517
Query: 6222 TNDCYDGSDEKD--CFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCA 6049
NDC DGSDE+ CF + P C++ +F C +R C+ H C+G DC
Sbjct: 2518 ENDCVDGSDEEIHLCF----------NVP--CESPQRFRCDNSR-CIYGHQLCNGVDDCG 2564
Query: 6048 DGSDEKNCDAKK-----CTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQC 5905
DGSDEK +K CT E+ C S+ C+ CD DC D DE C
Sbjct: 2565 DGSDEKEEHCRKPTHKPCTDTEYKC-SNGNCVSQHYVCDNVDDCGDLSDETGC 2616
Score = 136 bits (342), Expect = 8e-30
Identities = 107/384 (27%), Positives = 177/384 (45%), Gaps = 23/384 (5%)
Frame = -1
Query: 5226 RSPS----CPKANCSHFCI--DRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYG 5065
R PS C A CSH C+ + + C C G+ LS++ +C R D + ++ V
Sbjct: 349 RQPSSPNPCASATCSHLCLLSAQEPRHYSCACPSGWNLSDDSVNCVRGD--QPFLISVRE 406
Query: 5064 HRLKLFTIDGHAKAT----LLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQP 4897
+ + ++D K+ +S + +G +++D +YW + N I +
Sbjct: 407 NVIFGISLDPEVKSNDAMVPISGIQHGYDVEFDDSEQFIYWVE-----NPGEIHRVKTDG 461
Query: 4896 NTYRVINSLPTKGID-GIAVDWLGRNIYYTDRNHDAIAVCDMRG--RFNRILLK--GTPL 4732
+ L G G+A+DW+ RNIYYT +I V +RG R+ + L+ GTPL
Sbjct: 462 SNRTAFAPLSLLGSSLGLALDWVSRNIYYTTPASRSIEVLTLRGDTRYGKTLITNDGTPL 521
Query: 4731 ND--PRAIVLDPLQALVFW----TDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVD 4570
P I +DP + ++W TD G A I NMDG++ +++ + + +D
Sbjct: 522 GVGFPVGIAVDPARGKLYWSDHGTDSGVPAKIASANMDGTSLKILFTGN-MEHLEVVTLD 580
Query: 4569 APAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERV 4390
Q+LY+ R I N DG++R M+L + H + L V ++Y+SD IERV
Sbjct: 581 IQEQKLYWAVTSRGVIERGNVDGTER-MILVHHLAHPWGLVVHGSFLYYSDEQYEVIERV 639
Query: 4389 HKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDNLCIPANTPDL 4210
K +G+N KV+ +D G ++ H + ++ + P C +C+P
Sbjct: 640 DKSSGSN-KVVFRDNIPYLRGLRVYH----HRNAADSSNGCSNNPNACQQICLP------ 688
Query: 4209 TTSSDNFTCMCAQGFR--SEGRSC 4144
F+C CA GF+ +GRSC
Sbjct: 689 -VPGGMFSCACASGFKLSPDGRSC 711
Score = 124 bits (312), Expect = 2e-26
Identities = 108/336 (32%), Positives = 144/336 (42%), Gaps = 22/336 (6%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADES---NC---TCNENEF 6412
D+ DT S C F+C NG CI VC+ NDC + +DE +C C+ EF
Sbjct: 1548 DEPDTCGHSLNSCSANQFHCDNGRCISSSWVCDGDNDCGDMSDEDQRHHCELQNCSSTEF 1607
Query: 6411 RC-----QSGACIPSKARCNHMQDCNDASDEI-GCPFRNCSALNEFGMTGLINCATTSQC 6250
C + CIP C+ DC DA DE+ C R CS TG +CA +C
Sbjct: 1608 TCINSRPPNRRCIPQHWVCDGDADCADALDELQNCTMRACS-------TGEFSCA-NGRC 1659
Query: 6249 IHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQC 6070
I S++CD NDC D SDE+ C S P D QF C C+ K + C
Sbjct: 1660 IRQSFRCDRRNDCGDYSDERGC-----------SYPPCRD--DQFTC-QNGQCITKLYVC 1705
Query: 6069 DGQPDCADGSDEKN--CDAKK--CTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCE 5902
D DC DGSDE+ C + C +F C++ CI + C+ DC D DE C
Sbjct: 1706 DEDNDCGDGSDEQEHLCHTPEPTCPPHQFRCDNG-HCIEMGTVCNHVDDCSDNSDEKGCG 1764
Query: 5901 -TEC-DSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSR 5728
EC DS + CT+ ++ C C+ K L SD+ C P
Sbjct: 1765 INECQDSSISHCDHNCTD---TITSFYC----SCLPGYK-LMSDKRTCVDIDECKETPQL 1816
Query: 5727 CADETCVVACELTAVLCDGIQDCSDGF----DEKNC 5632
C+ + CE V+ I C+ G+ D K+C
Sbjct: 1817 CSQK-----CE--NVIGSYICKCAPGYIREPDGKSC 1845
Score = 112 bits (281), Expect = 9e-23
Identities = 100/376 (26%), Positives = 164/376 (43%), Gaps = 11/376 (2%)
Frame = -1
Query: 5232 CLRSPSCPKANCSHFCIDRRDVGHQCFCAPGYILSENQKDCRR-NDTIEAEIL-MVYGHR 5059
C +P+ C C+ C CA G+ LS + + C N I +L V G
Sbjct: 675 CSNNPNA----CQQICLPVPGGMFSCACASGFKLSPDGRSCSPYNSFIVVSMLPAVRGFS 730
Query: 5058 LKLFTIDGHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKA-GITSMSNQPNTYR- 4885
L+L + A + N + D DV + +YW D + + GI + + +
Sbjct: 731 LEL-SDHSEAMVPVAGQGRNVLHADVDVANGFIYWCDFSSSVRSSNGIRRIKPNGSNFTN 789
Query: 4884 -VINSLPTKGIDGIAVDWLGRNIYYTDR--NHDAIAVCDMRGRFNRILLKGTPLNDPRAI 4714
V + GI G+AVDW+ N+Y+T+ I V + + R+LLK ++ PR I
Sbjct: 790 IVTYGIGANGIRGVAVDWVAGNLYFTNAFVYETLIEVIRINTTYRRVLLK-VSVDMPRHI 848
Query: 4713 VLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAH 4534
V+DP +FW D+G I R +D +N V++ + + P LAVD +Y+ D
Sbjct: 849 VVDPKHRYLFWADYGQKPKIERSFLDCTNRTVLVSEGIVT-PRGLAVDHDTGYIYWVDDS 907
Query: 4533 RDYIASCNYDGSKRRMVLRGS-VRHIFALAVFEDYVYWSDWHNHTIERVHKITG-TNRKV 4360
D IA + DG + ++V GS + + VF + + W D + + + K G T+
Sbjct: 908 LDIIARIHRDGGESQVVRYGSRYPTPYGITVFGESIIWVDRNLRKVFQASKQPGNTDPPT 967
Query: 4359 LIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQP-ARCDNLCIPANTPDLTTSSDNFTC 4183
+I+D I +Q + + +PC Q C + C P+L T C
Sbjct: 968 VIRDSINLLRDVTIFDEHVQPLSPAELNNNPCLQSNGGCSHFCFA--LPELPTPK----C 1021
Query: 4182 MCAQG-FRSEGRSCVS 4138
CA G +G++C +
Sbjct: 1022 GCAFGTLEDDGKNCAT 1037
Score = 100 bits (249), Expect = 5e-19
Identities = 75/248 (30%), Positives = 108/248 (43%), Gaps = 17/248 (6%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCT--------CNEN 6418
D+ D + C + C P +F C +G C+P+ C+ DC + +DES C C
Sbjct: 2440 DNSDERDCEMKTCHPEHFQCTSGHCVPKALACDGRADCLDASDESACPTRFPNGTYCPAA 2499
Query: 6417 EFRCQSGACIPSKARCNHMQDCNDASD-EIGCPFR-NCSALNEFGMTGLINCATTSQCIH 6244
F C++ CI S C+ DC D SD EI F C + F S+CI+
Sbjct: 2500 MFECKNHVCIQSFWICDGENDCVDGSDEEIHLCFNVPCESPQRFR-------CDNSRCIY 2552
Query: 6243 PSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDG 6064
C+G +DC DGSDEK+ + C T++ C + C+ +H+ CD
Sbjct: 2553 GHQLCNGVDDCGDGSDEKEEHCR-------KPTHKPC-TDTEYKC-SNGNCVSQHYVCDN 2603
Query: 6063 QPDCADGSDEKNCD-AKKCTSFEFSCESSKKCIPLEQK---CDGRRDC-PDGEDEHQCE- 5902
DC D SDE C+ + T E CE + C L C R P D++ C+
Sbjct: 2604 VDDCGDLSDETGCNLGENRTCAEKICE--QNCTQLSNGGFICSCRPGFKPSTLDKNSCQD 2661
Query: 5901 -TECDSKG 5881
EC+ G
Sbjct: 2662 INECEEFG 2669
Score = 59.3 bits (142), Expect = 1e-06
Identities = 81/386 (20%), Positives = 135/386 (33%), Gaps = 4/386 (1%)
Frame = -1
Query: 2814 CAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQVSV 2635
C Q C C CA G+ + D C P + + + R + L + ++
Sbjct: 682 CQQICLPVPGGMFSCACASGF-KLSPDGRSCSPYNSFIVVSMLPAVRGFSLELSDHSEAM 740
Query: 2634 LRPVFNIKMNLIPGGIDFGYD-VFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEEST 2458
+ PV N++ +D ++ +V N I+ + I ++G +
Sbjct: 741 V-PVAGQGRNVLHADVDVANGFIYWCDFSSSVRSSNGIRRIKPNGSNFTNIVTYGIGANG 799
Query: 2457 AGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVD 2278
+ D++ N+YFT + F + I V + T R L+ S + VD
Sbjct: 800 IRGVAVDWVAGNLYFTNA--------FVYETLIEVIRINTTYRRVLLKVSVDMPRHIVVD 851
Query: 2277 PIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNER 2098
P R +FW P+I + LD LV I P + +D
Sbjct: 852 PKHRYLFWADYGQKPKIERSFLD-----------CTNRTVLVSEGIVTPRGLAVDHDTGY 900
Query: 2097 LYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITRQ-GSIHRMHKFT 1921
+YW+D I + DG + + VR TP + V G I + R + + K
Sbjct: 901 IYWVDDSLDIIARIHRDGGESQVVRYGSRYPTPYGITVFGESIIWVDRNLRKVFQASKQP 960
Query: 1920 GKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPC--QSDYCPSNTVCVPDQDKNG 1747
G T+ ++ + + +S NPC + C +P+
Sbjct: 961 GNTDPPTVIRDSINLLRDVTIFDEHVQPLSPAELNNNPCLQSNGGCSHFCFALPE----- 1015
Query: 1746 ILIPKCLCGPGRFFEVSTKKCMQLRE 1669
+ PKC C G E K C RE
Sbjct: 1016 LPTPKCGCAFGT-LEDDGKNCATSRE 1040
Score = 57.8 bits (138), Expect = 4e-06
Identities = 79/360 (21%), Positives = 149/360 (40%), Gaps = 11/360 (3%)
Frame = -1
Query: 2835 ECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECE-PLSKSAEMFITNGNRLHLMS 2659
EC G C+Q C + + RC C P Y ++D C+ S++ + + + +++ + +
Sbjct: 46 ECDIPGFCSQHC-VNMRGSFRCACDPEYT-LESDGRTCKVTASENLLLVVASRDKIIMDN 103
Query: 2658 LENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGS 2479
+ ++ V ++ + VF + L+ K WS G+
Sbjct: 104 ITAHTHNIYSLVQDVSFVVALDFDSVTGRVFWSDLL------------EGKTWSAFQNGT 151
Query: 2478 WGEEESTAGL-----ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIV 2314
+GL I D++ N+Y+T+ + + I V+K D S RT+++
Sbjct: 152 DKRVVHDSGLSLTEMIAVDWIGRNIYWTDYTLET----------IEVSKI-DGSHRTVLI 200
Query: 2313 NSTGTI-NSLAVDPIK--RLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERN 2143
+ T LA+DP ++FW+ PRI A++DG +V+
Sbjct: 201 SKNVTKPRGLALDPRMGDNVMFWSDWGHHPRIERASMDG-----------TMRTVIVQEK 249
Query: 2142 IFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELG-DTPVTMDVLGGYIY 1966
I+ P + +D+ N +Y++D IE +DG++RR V +L P + + ++
Sbjct: 250 IYWPCGLSIDYPNRLIYFMDAYLDYIEFCDYDGQNRRQVIASDLVLHHPHALTLFEDSVF 309
Query: 1965 LITR-QGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYC 1789
R + + +K+ G+ V + V + I HP++ S NPC S C
Sbjct: 310 WTDRGTHQVMQANKWHGRNQSVV--MYSVPQPLGIIAIHPSRQPSS-----PNPCASATC 362
Score = 55.1 bits (131), Expect = 2e-05
Identities = 66/278 (23%), Positives = 89/278 (31%), Gaps = 9/278 (3%)
Frame = -1
Query: 5916 EHQCETECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAA--GRTSF 5743
+ QC CD G + C P C + + L +D C G
Sbjct: 1301 QQQCSNPCDQFNGGCSHICAPG---PNGAECQCPHE---GSWYLANDNKYCVVDTGARCN 1354
Query: 5742 HVPSRCADETCVVACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSG 5563
C + C+ CD DC DG DE C+ + C +G+C+
Sbjct: 1355 QFQFTCLNGRCISQ----DWKCDNDNDCGDGSDELPTVCAFHTCRSTAFTCANGRCVPYH 1410
Query: 5562 RLCDASVDCVDGSDEWVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCM- 5386
CD DC D SDE C R C S +NG C+ +C+G +C
Sbjct: 1411 YRCDFYNDCGDNSDE--AGCLF-----RSCNSTTEFTCSNGR--CIPLSYVCNGINNCHD 1461
Query: 5385 SGIDEQCDNPQGNCSSTRNSCDQTWNCQRHAGF--ESCSCDDGYHLSPYDKKTCLRSPSC 5212
+ ++ + P C C T C A C DG S
Sbjct: 1462 NDTSDEKNCPPITCQPDFAKCQTTNICVPRAFLCDGDNDCGDG-------------SDEN 1508
Query: 5211 PKANCSHFCIDRRDVGHQCF----CAPGYILSENQKDC 5110
P SH C R QC C P Y + + DC
Sbjct: 1509 PIYCASHTC---RSNEFQCVSPHRCIPSYWFCDGEADC 1543
Score = 50.1 bits (118), Expect = 7e-04
Identities = 87/405 (21%), Positives = 131/405 (31%), Gaps = 35/405 (8%)
Frame = -1
Query: 1821 HQKNPCQSDY--------CPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQLREK 1666
H + C+++Y C C + D+ G C P F C+ LR K
Sbjct: 2335 HTEFSCKTNYRCIPQWAVCNGFDDCRDNSDEQGC--ESVPCHPSGDFRCGNHHCIPLRWK 2392
Query: 1665 DQEASQCGDYFCYNNAGCSPQKTCVCPPGFYGRQC--------EINECSETCWNGE---- 1522
CGD + C P++ +QC + N+C + +
Sbjct: 2393 CDGIDDCGDNS--DEESCVPRECTESEFRCADQQCIPSRWVCDQENDCGDNSDERDCEMK 2450
Query: 1521 TCAVQEFGSTTNVVCHCPSNYT----QSSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSY 1354
TC + F T+ HC ++ C E C R T CP C+++
Sbjct: 2451 TCHPEHFQCTSG---HCVPKALACDGRADCLDASDESACPTRFPNGTY-CPAAMFECKNH 2506
Query: 1353 ----SFCECDKGWTGPHCRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQN 1186
SF CD C +D ++ H C E P RC +RC
Sbjct: 2507 VCIQSFWICDGE---NDCVDGSDEEI---HLCFNVPC--ESPQRFRCD------NSRC-- 2550
Query: 1185 CVGHECLNGGFCSYANSNRSLPHCICPSGFTGDHCE--EYLCKDACPFGSKCTYDITKPM 1012
GH+ NG S+ HC P T C EY C + D
Sbjct: 2551 IYGHQLCNGVDDCGDGSDEKEEHCRKP---THKPCTDTEYKCSNGNCVSQHYVCDNVDDC 2607
Query: 1011 DPITCSCEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPR----- 847
++ N + T IC++ NGG C C P F
Sbjct: 2608 GDLSDETGCNLGENRTCAEKICEQNCTQLSNGGFI---------CSCRPGFKPSTLDKNS 2658
Query: 846 CDVPVQCDDYCTNNSKCTITNGTHFECDCKPGFKGLRCEQETKCS 712
C +C+++ C + G+ +EC C GFK + +C+
Sbjct: 2659 CQDINECEEFGICPQSCRNSKGS-YECFCVDGFKSMSTHYGERCA 2702
Score = 40.0 bits (92), Expect = 0.77
Identities = 22/74 (29%), Positives = 33/74 (43%), Gaps = 1/74 (1%)
Frame = -1
Query: 600 HQLECKNGGY-CLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCLHDGNCTLDEYFEP 424
H + GGY C P S T T C + + + C C+H G+C DE P
Sbjct: 2994 HLCLLRPGGYSCACPQGSDFVTGSTVECDAASELPITMPSPCR--CMHGGSCYFDENDLP 3051
Query: 423 QCECYQAFIGDRCQ 382
+C+C + G+ C+
Sbjct: 3052 KCKCSSGYSGEYCE 3065
>gi|6806919|ref|NP_004516.1| low density lipoprotein-related protein
2; megalin; calcium sensor protein; Heymann nephritis
antigen homolog [Homo sapiens]
gi|6166537|sp|P98164|LRP2_HUMAN Low-density lipoprotein
receptor-related protein 2 precursor (Megalin)
(Glycoprotein 330) (gp330)
gi|1809240|gb|AAB41649.1| gp330 precursor [Homo sapiens]
Length = 4655
Score = 728 bits (1879), Expect = 0.0
Identities = 544/1819 (29%), Positives = 801/1819 (43%), Gaps = 147/1819 (8%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCT---CNEN-EFRCQ 6403
DE C+ C P F C NG C+ C+ NDC + +DE+ C CN EF C
Sbjct: 2730 DEMESVCALHTCSPTAFTCANGRCVQYSYRCDYYNDCGDGSDEAGCLFRDCNATTEFMCN 2789
Query: 6402 SGACIPSKARCNHMQDCND--ASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKC 6229
+ CIP + CN + +C+D SDE CP R C + G C ++ CI + C
Sbjct: 2790 NRRCIPREFICNGVDNCHDNNTSDEKNCPDRTCQS-------GYTKCHNSNICIPRVYLC 2842
Query: 6228 DGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCA 6049
DG NDC D SDE + +C + ++F C + R C+P+HW CD + DC
Sbjct: 2843 DGDNDCGDNSDENPTYC----------TTHTCSS-SEFQCASGR-CIPQHWYCDQETDCF 2890
Query: 6048 DGSDEK-NC--DAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDE---HQCETECDS 5887
D SDE +C + C + EF C+ + CIP E CDG DC D DE HQC+ + S
Sbjct: 2891 DASDEPASCGHSERTCLADEFKCDGGR-CIPSEWICDGDNDCGDMSDEDKRHQCQNQNCS 2949
Query: 5886 KGGNATFRCTN-----HRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCA 5722
++ F C N RCIP +W CDG DC D G DE RT C
Sbjct: 2950 ---DSEFLCVNDRPPDRRCIPQSWVCDGDVDCTD-----GYDENQNCTRRTCSENEFTCG 3001
Query: 5721 DETCVVACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASV 5542
C+ CD DC D DE+ C L + C+ N++ C +G+CI +CD
Sbjct: 3002 YGLCIPKI----FRCDRHNDCGDYSDERGC--LYQTCQQNQFTCQNGRCISKTFVCDEDN 3055
Query: 5541 DCVDGSDEWVEICSLSEPPRRGCPSG-WSCLLTNGTIGCLQEQQLCDGRRDCMSGIDE-- 5371
DC DGSDE + +C EP CP + C NG C++ +LC+ DC+ DE
Sbjct: 3056 DCGDGSDELMHLCHTPEPT---CPPHEFKC--DNGR--CIEMMKLCNHLDDCLDNSDEKG 3108
Query: 5370 ----QCDNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKA 5203
+C +P + + CD NC CSC GY L DK+TC+ C +
Sbjct: 3109 CGINECHDP------SISGCDH--NCTDTLTSFYCSCRPGYKLMS-DKRTCVDIDECTEM 3159
Query: 5202 N--CSHFCIDRRDVG-HQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGH 5032
CS C +G + C CAPGY+ + K CR+N IE ++ + L+ TIDG+
Sbjct: 3160 PFVCSQKC--ENVIGSYICKCAPGYLREPDGKTCRQNSNIEPYLIFSNRYYLRNLTIDGY 3217
Query: 5031 AKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINS-LPTKGI 4855
+ +L L N VALD+D +YW D + N+ N +IN LP
Sbjct: 3218 FYSLILEGLDNVVALDFDRVEKRLYWIDTQRQVIER---MFLNKTNKETIINHRLPAA-- 3272
Query: 4854 DGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTP-------LNDPRAIVLDPLQ 4696
+ +AVDW+ R +Y+ D D + V D+ G R+L + ++PR + L P
Sbjct: 3273 ESLAVDWVSRKLYWLDARLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLALHPQY 3332
Query: 4695 ALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIAS 4516
++W DWG A+IGR+ MDG+N+ VI+ + + WPN + +D LY+ DAH YI
Sbjct: 3333 GYLYWADWGHRAYIGRVGMDGTNKSVIISTK-LEWPNGITIDYTNDLLYWADAHLGYIEY 3391
Query: 4515 CNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYR 4336
+ +G R V G++ H FA+ +FED +YW+DW+ T+E+ +K G+NR+ L+ + +R
Sbjct: 3392 SDLEGHHRHTVYDGALPHPFAITIFEDTIYWTDWNTRTVEKGNKYDGSNRQTLV-NTTHR 3450
Query: 4335 PMGFKIVHPSLQSMGSLKTARHPC-SQPARCDNLCIPANTPDLTTSSDNFTCMCAQGFR- 4162
P + HP Q + S +PC + C +LC+ + FTC C FR
Sbjct: 3451 PFDIHVYHPYRQPIVS-----NPCGTNNGGCSHLCL------IKPGGKGFTCECPDDFRT 3499
Query: 4161 ---SEGRSCVSECKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIA 3991
S C+ C F+C KCI WW+ +CP C
Sbjct: 3500 LQLSGSTYCMPMCSSTQFLCANNEKCIPIWWKCDGQKDCSDGSDEL----ALCPQRFCRL 3555
Query: 3990 GQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIP 3811
GQF C + C LC+ ++C G DE+ CEN C +++C + K+CIP
Sbjct: 3556 GQFQC------SDGNCTSPQTLCNAHQNCPDGSDEDRLLCENHHCDSNEWQCAN-KRCIP 3608
Query: 3810 LTSVCDKEKDCDDGSDE--LNCEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQ 3637
+ CD DC+D SDE +C +C+P F C NG +CIP+ + CD ++DC +
Sbjct: 3609 ESWQCDTFNDCEDNSDEDSSHCASRTCRPGQFRCANG----RCIPQAWKCDVDNDCGDHS 3664
Query: 3636 DEP-DSCFGIGEC--THEQFQC-TSGKCIPKRRQCDGTLDCRDGSDEKGC-KKECAIVCD 3472
DEP + C +F C T+ +CIPK C+G DCRD SDE+GC ++ C V D
Sbjct: 3665 DEPIEECMSSAHLCDNFTEFSCKTNYRCIPKWAVCNGVDDCRDNSDEQGCEERTCHPVGD 3724
Query: 3471 -----NSCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKE----NRKC--GGFACDGIV 3325
+ C+ CDG+ C D S DEE C ++ E E N++C + CD
Sbjct: 3725 FRCKNHHCIPLRWQCDGQNDCGDNS--DEENCAPRECTESEFRCVNQQCIPSRWICDHYN 3782
Query: 3324 DCEDGSDEKGCPDLECH---------LASNKSLICDGTIDCSSGKDENNCHNN------G 3190
DC D SDE+ C CH + L CDG+ DC DE +C
Sbjct: 3783 DCGDNSDERDCEMRTCHPEYFQCTSGHCVHSELKCDGSADCLDASDEADCPTRFPDGAYC 3842
Query: 3189 ESNFFQCSMQT-IKEWQVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCLDVST 3013
++ F+C I + CDG DC DG DE +C CD+ + C+ S
Sbjct: 3843 QATMFECKNHVCIPPYWKCDGDDDCGDGSDEELHLCLDVPCNSPNRFRCDNNR-CI-YSH 3900
Query: 3012 ALCDGIRDCFDGSDENPIHC-----KDMCKGKYRCTNGRCI-------DVSARXXXXXXX 2869
+C+G+ DC DG+DE HC K + +Y+C NG CI D
Sbjct: 3901 EVCNGVDDCGDGTDETEEHCRKPTPKPCTEYEYKCGNGHCIPHDNVCDDADDCGDWSDEL 3960
Query: 2868 XXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFI 2689
AE +C Q C C C G+ D C +++ E F
Sbjct: 3961 GCNKGKERTCAE----NICEQNCTQLNEGGFICSCTAGFETNVFDRTSCLDINE-CEQFG 4015
Query: 2688 TNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRS 2509
T H + + S V F M+ PG + L+ + + ++ S
Sbjct: 4016 TCPQ--HCRNTKGSYECVCADGFT-SMSDRPGK-RCAAEGSSPLLLLPDNVRIRKYNLSS 4071
Query: 2508 KKWSDGLIGSWGEEESTAGLITYDFMHNN-----VYFTESSEQNR--------------- 2389
+++S+ L ++E + YD+ + VY+T E +R
Sbjct: 4072 ERFSEYL-----QDEEYIQAVDYDWDPKDIGLSVVYYTVRGEGSRFGAIKRAYIPNFESG 4126
Query: 2388 -------------------GVLFD-----------RQANIYVAKAKDTSTRTLIVNSTGT 2299
G+ D + I VAK + LI
Sbjct: 4127 RNNLVQEVDLKLKYVMQPDGIAVDWVGRHIYWSDVKNKRIEVAKLDGRYRKWLISTDLDQ 4186
Query: 2298 INSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMV 2119
++AV+P L+FWT P+I SA ++G + LV ++ PT +
Sbjct: 4187 PAAIAVNPKLGLMFWTDWGKEPKIESAWMNG-----------EDRNILVFEDLGWPTGLS 4235
Query: 2118 LDF-SNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITRQ-GS 1945
+D+ +N+R+YW D + IET+ +DG DRR + K + P ++D+ +Y I+++ G
Sbjct: 4236 IDYLNNDRIYWSDFKEDVIETIKYDGTDRRVIAKEAM--NPYSLDIFEDQLYWISKEKGE 4293
Query: 1944 IHRMHKFTGKTNKYVQKIREVSPRI-QIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCV 1768
+ + +KF G+ K +K V+P + Q+R+ H ++ S K C S C
Sbjct: 4294 VWKQNKF-GQGKK--EKTLVVNPWLTQVRIFHQLRYNKSVPNLCKQIC-SHLC------- 4342
Query: 1767 PDQDKNGILIP---KCLCGPG-RFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCSPQK 1600
+L P C C G F E ST +C E C + C +
Sbjct: 4343 -------LLRPGGYSCACPQGSSFIEGSTTECDAAIELPINLPP--PCRCMHGGNCYFDE 4393
Query: 1599 T----CVCPPGFYGRQCEI 1555
T C CP G+ G+ CE+
Sbjct: 4394 TDLPKCKCPSGYTGKYCEM 4412
Score = 372 bits (956), Expect = e-101
Identities = 261/820 (31%), Positives = 382/820 (45%), Gaps = 17/820 (2%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC-----TCNENEFR 6409
+ + T T C F C NG C+P +C+ ++DC + +DE C TC+ + F
Sbjct: 1014 EGDPTNEPPTEQCGLFSFPCKNGRCVPNYYLCDGVDDCHDNSDEQLCGTLNNTCSSSAFT 1073
Query: 6408 CQSGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKC 6229
C G CIP+ RC+ DC D SDE CP ++ + T QCI +W C
Sbjct: 1074 CGHGECIPAHWRCDKRNDCVDGSDEHNCPTHAPASCLDTQYT-----CDNHQCISKNWVC 1128
Query: 6228 DGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCA 6049
D NDC DGSDEK+C ++ +C +QF C C+ + CDG DC
Sbjct: 1129 DTDNDCGDGSDEKNC-----------NSTETCQ-PSQFNC-PNHRCIDLSFVCDGDKDCV 1175
Query: 6048 DGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNAT 5869
DGSDE C CT+ +F C S KCI + +CDG DC D DE C T +
Sbjct: 1176 DGSDEVGC-VLNCTASQFKCASGDKCIGVTNRCDGVFDCSDNSDEAGCPTRPPGMCHSDE 1234
Query: 5868 FRCTNHR-CIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACEL 5692
F+C CIP W CDG DC+ GSDE + +T C + C+
Sbjct: 1235 FQCQEDGICIPNFWECDGHPDCL-----YGSDEHNACVPKTCPSSYFHCDNGNCI----H 1285
Query: 5691 TAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMC-DSGQCIDSGRLCDASVDCVDGSDEW 5515
A LCD DC D DEK+C + +C +W C C++ +CD DC +G+DE
Sbjct: 1286 RAWLCDRDNDCGDMSDEKDCPTQPFRCPSWQWQCLGHNICVNLSVVCDGIFDCPNGTDE- 1344
Query: 5514 VEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSST 5335
+C +G SC NG GC E C+ + N C
Sbjct: 1345 SPLC-----------NGNSCSDFNG--GCTHECVQEPFGAKCLCPLGFLLANDSKTCEDI 1391
Query: 5334 RNSCDQTWNCQRHA----GFESCSCDDGYHLSPYDKKTCLRSPSCPKANCSHFCIDRRDV 5167
+ CD +C +H G CSCD GY L D +TC K S +
Sbjct: 1392 -DECDILGSCSQHCYNMRGSFRCSCDTGYMLES-DGRTC-------KVTASESLL----- 1437
Query: 5166 GHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLTNGVAL 4987
+ S+N+ D++ +++ +Y +L+ N + VA+
Sbjct: 1438 --------LLVASQNKIIA---DSVTSQVHNIY---------------SLVENGSYIVAV 1471
Query: 4986 DYDVKSDLVYWTDVAHDGNKAGITSMSNQPNT-YRVINSLPTKGIDGIAVDWLGRNIYYT 4810
D+D S ++W+D G T + Q T RV+ + IA+DW+GRN+Y+T
Sbjct: 1472 DFDSISGRIFWSDATQ-----GKTWSAFQNGTDRRVVFDSSIILTETIAIDWVGRNLYWT 1526
Query: 4809 DRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPL--QALVFWTDWGASAHIGRMNMD 4636
D + I V + G +L+ L +PR + LDP + L+FW+DWG I R +MD
Sbjct: 1527 DYALETIEVSKIDGSHRTVLISKN-LTNPRGLALDPRMNEHLLFWSDWGHHPRIERASMD 1585
Query: 4635 GSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGS--VRH 4462
GS VI+QD+ I WP L +D P + LYF D++ DY+ C+Y+G RR V+ +RH
Sbjct: 1586 GSMRTVIVQDK-IFWPCGLTIDYPNRLLYFMDSYLDYMDFCDYNGHHRRQVIASDLIIRH 1644
Query: 4461 IFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLK 4282
+AL +FED VYW+D + R +K G N+ V++ + Q+ P+G VHPS Q
Sbjct: 1645 PYALTLFEDSVYWTDRATRRVMRANKWHGGNQSVVMYNIQW-PLGIVAVHPSKQ-----P 1698
Query: 4281 TARHPCSQPARCDNLCIPANTPDLTTSSDNF-TCMCAQGF 4165
+ +PC+ +RC +LC+ L++ +F +C+C G+
Sbjct: 1699 NSVNPCAF-SRCSHLCL------LSSQGPHFYSCVCPSGW 1731
Score = 349 bits (895), Expect = 6e-94
Identities = 427/1791 (23%), Positives = 678/1791 (37%), Gaps = 184/1791 (10%)
Frame = -1
Query: 5247 YDKKTCLRSPS------CPKAN--CSHFCIDRRDVGH-QCFCAPGYILSENQKDCRRNDT 5095
+DK+ RSP+ C + N CSH C + +C CA G + S+ +N
Sbjct: 2329 FDKQVQPRSPAEVNNNPCLENNGGCSHLCFALPGLHTPKCDCAFGTLQSDG-----KNCA 2383
Query: 5094 IEAEILMVYGHRLKLFTI----DGHAKATLLSNLTNGV-ALDYDVKSDLVYWT-DVAHDG 4933
I E +++ L ++ + H+ N+ V +LDYD SD +Y+T ++A
Sbjct: 2384 ISTENFLIFALSNSLRSLHLDPENHSPPFQTINVERTVMSLDYDSVSDRIYFTQNLASGV 2443
Query: 4932 NKAGITSMSNQPNTYRVINSLPTKGI---DGIAVDWLGRNIYYTDRNHDAIAVCDMRGRF 4762
+ ++S+ +T VI S GI DGIA DW+ R IYY+D + I G
Sbjct: 2444 GQISYATLSSGIHTPTVIAS----GIGTADGIAFDWITRRIYYSDYLNQMINSMAEDGS- 2498
Query: 4761 NRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNA 4582
NR ++ P PRAIVLDP Q ++W DW A I R + G N +V + + ++ P+
Sbjct: 2499 NRTVIARVP--KPRAIVLDPCQGYLYWADWDTHAKIERATL-GGNFRVPIVNSSLVMPSG 2555
Query: 4581 LAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHT 4402
L +D LY+ DA I G R +++ +V H F L ++ Y+YW+D +
Sbjct: 2556 LTLDYEEDLLYWVDASLQRIERSTLTGVDREVIVNAAV-HAFGLTLYGQYIYWTDLYTQR 2614
Query: 4401 IERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPAR-----CDNL 4237
I R +K G+ + + + +P G V +K + C+ P C ++
Sbjct: 2615 IYRANKYDGSGQIAMTTNLLSQPRGINTV---------VKNQKQQCNNPCEQFNGGCSHI 2665
Query: 4236 CIPANTPDLTTSSDNFTCMCAQG----FRSEGRSCVSE----CKPNDFVCTKTYKCISSW 4081
C P + C C + + C+ + C + F C+ +CIS
Sbjct: 2666 CAPG--------PNGAECQCPHEGNWYLANNRKHCIVDNGERCGASSFTCSNG-RCISEE 2716
Query: 4080 WRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCS 3901
W+ +E VC C F C A +C+ S CD DC
Sbjct: 2717 WKCDNDNDCGDGSDE---MESVCALHTCSPTAFTC------ANGRCVQYSYRCDYYNDCG 2767
Query: 3900 GGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDG--SDELNCEITSCKPD 3727
G DE + T +F C +++ CIP +C+ +C D SDE NC +C+
Sbjct: 2768 DGSDEAGCLFRDCNAT-TEFMCNNRR-CIPREFICNGVDNCHDNNTSDEKNCPDRTCQSG 2825
Query: 3726 FFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQ 3547
+ C N CIP+ + CDG++DC + DE + C+ +FQC SG+CIP+
Sbjct: 2826 YTKCHNSNI---CIPRVYLCDGDNDCGDNSDENPTYCTTHTCSSSEFQCASGRCIPQHWY 2882
Query: 3546 CDGTLDCRDGSDEKGC----KKECA---IVCDNS-CVHADDLCDGKKKCNDGSDEDEE-A 3394
CD DC D SDE ++ C CD C+ ++ +CDG C D SDED+
Sbjct: 2883 CDQETDCFDASDEPASCGHSERTCLADEFKCDGGRCIPSEWICDGDNDCGDMSDEDKRHQ 2942
Query: 3393 CVIKQLLEKE---------NRKC--GGFACDGIVDCEDGSDE-KGCPDLECH-------- 3274
C + + E +R+C + CDG VDC DG DE + C C
Sbjct: 2943 CQNQNCSDSEFLCVNDRPPDRRCIPQSWVCDGDVDCTDGYDENQNCTRRTCSENEFTCGY 3002
Query: 3273 -LASNKSLICDGTIDCSSGKDENNC-HNNGESNFFQCSM-QTIKEWQVCDGRWDCADGLD 3103
L K CD DC DE C + + N F C + I + VCD DC DG D
Sbjct: 3003 GLCIPKIFRCDRHNDCGDYSDERGCLYQTCQQNQFTCQNGRCISKTFVCDEDNDCGDGSD 3062
Query: 3102 ESPEMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDE-----NPIHCKDMCK 2938
E +C + + C + D +C+++ LC+ + DC D SDE N H +
Sbjct: 3063 ELMHLCHTPEPTCPPHEFKCDNGRCIEMMK-LCNHLDDCLDNSDEKGCGINECHDPSISG 3121
Query: 2937 GKYRCTNGRCIDVSARXXXXXXXXXXXXXXXXGAECHHFG-VCAQKCWMAFNHTARCHCA 2761
+ CT+ EC VC+QKC C CA
Sbjct: 3122 CDHNCTD-TLTSFYCSCRPGYKLMSDKRTCVDIDECTEMPFVCSQKCENVIGSYI-CKCA 3179
Query: 2760 PGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDF 2581
PGY R + D C + + E ++ NR +L +L ++ +++ + + +
Sbjct: 3180 PGYLR-EPDGKTCRQ-NSNIEPYLIFSNRYYLRNL-----TIDGYFYSLILEGLDNVVAL 3232
Query: 2580 GYDVFRTTLMYTVGIGNSRVD--IRSKKWSDGLIGSWGEEESTAGLITYDFMHNNVYFTE 2407
+D L Y + ++ +K + +I A + D++ +Y+ +
Sbjct: 3233 DFDRVEKRL-YWIDTQRQVIERMFLNKTNKETII---NHRLPAAESLAVDWVSRKLYWLD 3288
Query: 2406 SSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINS--------LAVDPIKRLIFWT 2251
+ R ++V+ R L + N+ LA+ P ++W
Sbjct: 3289 A----------RLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLYWA 3338
Query: 2250 TSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKR 2071
I +DG ++ + P + +D++N+ LYW D
Sbjct: 3339 DWGHRAYIGRVGMDG-----------TNKSVIISTKLEWPNGITIDYTNDLLYWADAHLG 3387
Query: 2070 TIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGKTNKYVQK 1894
IE +G R TV L P + + IY ++ + +K+ G + +
Sbjct: 3388 YIEYSDLEGHHRHTVYDGAL-PHPFAITIFEDTIYWTDWNTRTVEKGNKYDGSNRQTL-- 3444
Query: 1893 IREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLCGPG 1714
+ I V HP + + NPC ++ + +C+ G C C P
Sbjct: 3445 VNTTHRPFDIHVYHPYRQPI-----VSNPCGTNNGGCSHLCLIKPGGKGF---TCEC-PD 3495
Query: 1713 RFFEVSTKKCMQLREKDQEASQCG--DYFCYNNAGCSP-------QKTC--------VCP 1585
F + +QL C + C NN C P QK C +CP
Sbjct: 3496 DF------RTLQLSGSTYCMPMCSSTQFLCANNEKCIPIWWKCDGQKDCSDGSDELALCP 3549
Query: 1584 PGFYGRQCEINECSETCWNGETCAVQEFGSTTNVVCHCP--SNYTQSSCATNVCEGVCGP 1411
F C + + C +G + Q + N +CP S+ + C + C+
Sbjct: 3550 QRF----CRLGQFQ--CSDGNCTSPQ---TLCNAHQNCPDGSDEDRLLCENHHCD---SN 3597
Query: 1410 RGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHKADAKVCYGHCFSGGACDGEGPLNL 1231
C C + C +++ CE + HC + + C +G ++
Sbjct: 3598 EWQCANKRCIPESWQCDTFNDCEDNSDEDSSHCASRT-CRPGQFRCANGRCIPQAWKCDV 3656
Query: 1230 RCSCGDGLTGNRCQNCV--GHECLNGGFCSYANSNRSLPHCI-------CPSGFTGDHCE 1078
CGD + + C+ H C N S + R +P C CE
Sbjct: 3657 DNDCGDH-SDEPIEECMSSAHLCDNFTEFSCKTNYRCIPKWAVCNGVDDCRDNSDEQGCE 3715
Query: 1077 EYLCKDACPFGSKCTYDITKPMDPITCSCE-QNAAAHNTD---CSP--------ICQKQ- 937
E C F K + I P+ C+ QN N+D C+P C Q
Sbjct: 3716 ERTCHPVGDFRCKNHHCI-----PLRWQCDGQNDCGDNSDEENCAPRECTESEFRCVNQQ 3770
Query: 936 ---PNW-CHNGGRCLDTPGYPGKCK---CLPRF----------AGPRCDVPVQCDDYCTN 808
W C + C D C+ C P + + +CD C D ++
Sbjct: 3771 CIPSRWICDHYNDCGDNSD-ERDCEMRTCHPEYFQCTSGHCVHSELKCDGSADCLD-ASD 3828
Query: 807 NSKC-------TITNGTHFECD---CKPGFKGLRCEQETKCSECSNEA--KCIKKPSGT- 667
+ C T FEC C P + +C+ + C + S+E C+ P +
Sbjct: 3829 EADCPTRFPDGAYCQATMFECKNHVCIPPY--WKCDGDDDCGDGSDEELHLCLDVPCNSP 3886
Query: 666 --------------VIC----QCPQGLG--GEYCEKITATSCHQLECKNG-GYCLKPD-- 556
+C C G E+C K T C + E K G G+C+ D
Sbjct: 3887 NRFRCDNNRCIYSHEVCNGVDDCGDGTDETEEHCRKPTPKPCTEYEYKCGNGHCIPHDNV 3946
Query: 555 ----PSANRTSPTCLCSPGFKGLLCSSNACENFC--LHDGN--CTLDEYFE 427
S C+ G K C+ N CE C L++G C+ FE
Sbjct: 3947 CDDADDCGDWSDELGCNKG-KERTCAENICEQNCTQLNEGGFICSCTAGFE 3996
Score = 319 bits (817), Expect = 7e-85
Identities = 220/724 (30%), Positives = 333/724 (45%), Gaps = 16/724 (2%)
Frame = -1
Query: 6261 TSQCIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPK 6082
+ CI W+CDGT DC D +DE C V G F C + C+P
Sbjct: 37 SGHCIPADWRCDGTKDCSDDADEIGCAVVTCQQG-------------YFKCQSEGQCIPS 83
Query: 6081 HWQCDGQPDCADGSDEK-NCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQC 5905
W CD DC DGSDE+ +C C+S + +C S+ +CIP E +CD RDCPDG DE+ C
Sbjct: 84 SWVCDQDQDCDDGSDERQDCSQSTCSSHQITC-SNGQCIPSEYRCDHVRDCPDGADENDC 142
Query: 5904 E-TECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSR 5728
+ C+ C N C + +CD DC D+ SDE++C H
Sbjct: 143 QYPTCEQ------LTCDNGACYNTSQKCDWKVDCRDS-----SDEINCT--EICLHNEFS 189
Query: 5727 CADETCVVACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDA 5548
C + C+ A +CD DC DG DE C C ++ C SG+CI +CD
Sbjct: 190 CGNGECIP----RAYVCDHDNDCQDGSDEHACNY--PTCGGYQFTCPSGRCIYQNWVCDG 243
Query: 5547 SVDCVDGSDEWVEICSLSEPPRRGC-PSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDE 5371
DC D DE + C C P WSC + C+ ++CDG DC DE
Sbjct: 244 EDDCKDNGDE--DGCESGPHDVHKCSPREWSCPESG---RCISIYKVCDGILDCPGREDE 298
Query: 5370 QCDNPQGNCSSTR-NSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCP-KANC 5197
+ CS T ++ + + C +C C GY ++ D +TC+ C C
Sbjct: 299 NNTSTGKYCSMTLCSALNCQYQCHETPYGGACFCPPGYIINHNDSRTCVEFDDCQIWGIC 358
Query: 5196 SHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTI-EAEILMVYGHRLKLFTIDGHAKAT 5020
C + R H C C GYIL Q C+ ND+ EA I+ G L + I G +
Sbjct: 359 DQKC-ESRPGRHLCHCEEGYILERGQY-CKANDSFGEASIIFSNGRDLLIGDIHGRSFRI 416
Query: 5019 LLSNLTNGVALD--YDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGI 4846
L+ + GVA+ + V+WTD NK + N N V+N + + + +
Sbjct: 417 LVESQNRGVAVGVAFHYHLQRVFWTDTVQ--NKVFSVDI-NGLNIQEVLN-VSVETPENL 472
Query: 4845 AVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDW-- 4672
AVDW+ IY + + I + ++ G + R+ L L PR I +DP +F++DW
Sbjct: 473 AVDWVNNKIYLVETKVNRIDMVNLDGSY-RVTLITENLGHPRGIAVDPTVGYLFFSDWES 531
Query: 4671 -GASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSK 4495
+ R MDGSN + +++ + + WP + +D ++R+Y+ D+ DYI + YDG +
Sbjct: 532 LSGEPKLERAFMDGSNRKDLVKTK-LGWPAGVTLDMISKRVYWVDSRFDYIETVTYDGIQ 590
Query: 4494 RRMVLRGS--VRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFK 4321
R+ V+ G + H F +++FE V+++DW + + +K T TN +V Q RP G
Sbjct: 591 RKTVVHGGSLIPHPFGVSLFEGQVFFTDWTKMAVLKANKFTETNPQVYYQ-ASLRPYGVT 649
Query: 4320 IVHPSLQSMGSLKTARHPC-SQPARCDNLCIPANTPDLTTSSDNFTCMCAQGFR--SEGR 4150
+ H Q A +PC C+ +C+ ++ D F C C GF+ ++ R
Sbjct: 650 VYHSLRQPY-----ATNPCKDNNGGCEQVCVLSHRTD--NDGLGFRCKCTFGFQLDTDER 702
Query: 4149 SCVS 4138
C++
Sbjct: 703 HCIA 706
Score = 288 bits (736), Expect = 2e-75
Identities = 237/840 (28%), Positives = 363/840 (43%), Gaps = 63/840 (7%)
Frame = -1
Query: 5250 PYDKKTCLRSPSCPKANCSHFCI-----DRRDVGHQCFCAPGYILSENQKDCR--RNDTI 5092
PY C + C C+ D +G +C C G+ L +++ C +N I
Sbjct: 657 PYATNPCKDN----NGGCEQVCVLSHRTDNDGLGFRCKCTFGFQLDTDERHCIAVQNFLI 712
Query: 5091 EAEILMVYGHRLKLFTIDGHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITS 4912
+ + + G L T + + N + V +D+D + ++++D++ K I
Sbjct: 713 FSSQVAIRGIPFTLSTQED-VMVPVSGNPSFFVGIDFDAQDSTIFFSDMS----KHMIFK 767
Query: 4911 MSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPL 4732
++ + + ++ +A DW+ +N+Y+TD ++ +I+V + + R +++ L
Sbjct: 768 QKIDGTGREILAANRVENVESLAFDWISKNLYWTDSHYKSISVMRLADKTRRTVVQY--L 825
Query: 4731 NDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRL 4552
N+PR++V+ P +F+TDW A I R DGS+ ++ + T+ WPN LA+D A RL
Sbjct: 826 NNPRSVVVHPFAGYLFFTDWFRPAKIMRAWSDGSHLLPVI-NTTLGWPNGLAIDWAASRL 884
Query: 4551 YFGDAHRDYIASCNYDG-SKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITG 4375
Y+ DA+ D I +DG +RR+ + H F LA+F ++++++DW I RV K G
Sbjct: 885 YWVDAYFDKIEHSTFDGLDRRRLGHIEQMTHPFGLAIFGEHLFFTDWRLGAIIRVRKADG 944
Query: 4374 TNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPAR----CDNLCIPANTPDLT 4207
V+ Y I+H + +++T + C+QP C + C P
Sbjct: 945 GEMTVIRSGIAY------ILHLKSYDV-NIQTGSNACNQPTHPNGDCSHFCFPV------ 991
Query: 4206 TSSDNF--TCMCAQGFRSEGRSCVSECKPND-----------FVCTKTYKCISSWWRXXX 4066
NF C C G R E P + F C K +C+ +++
Sbjct: 992 ---PNFQRVCGCPYGMRLASNHLTCEGDPTNEPPTEQCGLFSFPC-KNGRCVPNYYLCDG 1047
Query: 4065 XXXXXXXXXXGYFVEGVCPPF--PCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGD 3892
E +C C + F CG +C+ A CD DC G
Sbjct: 1048 VDDCHDNSD-----EQLCGTLNNTCSSSAFTCGH------GECIPAHWRCDKRNDCVDGS 1096
Query: 3891 DEE--PAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEIT-SCKPDFF 3721
DE P C + Q+ C D +CI VCD + DC DGSDE NC T +C+P F
Sbjct: 1097 DEHNCPTHAP-ASCLDTQYTC-DNHQCISKNWVCDTDNDCGDGSDEKNCNSTETCQPSQF 1154
Query: 3720 ACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSG-KCIPKRRQC 3544
C N +CI F CDG+ DC +G DE + CT QF+C SG KCI +C
Sbjct: 1155 NCPN----HRCIDLSFVCDGDKDCVDGSDEVGC---VLNCTASQFKCASGDKCIGVTNRC 1207
Query: 3543 DGTLDCRDGSDEKGCKKECAIVC---------DNSCVHADDLCDGKKKCNDGSDEDEEAC 3391
DG DC D SDE GC +C D C+ CDG C GSDE AC
Sbjct: 1208 DGVFDCSDNSDEAGCPTRPPGMCHSDEFQCQEDGICIPNFWECDGHPDCLYGSDE-HNAC 1266
Query: 3390 VIK----QLLEKENRKC--GGFACDGIVDCEDGSDEKGCPD------------LECHLAS 3265
V K +N C + CD DC D SDEK CP L ++
Sbjct: 1267 VPKTCPSSYFHCDNGNCIHRAWLCDRDNDCGDMSDEKDCPTQPFRCPSWQWQCLGHNICV 1326
Query: 3264 NKSLICDGTIDCSSGKDENN-CHNNGESNF-FQCSMQTIKEWQVCDGRWDCADGLDESPE 3091
N S++CDG DC +G DE+ C+ N S+F C+ + ++E
Sbjct: 1327 NLSVVCDGIFDCPNGTDESPLCNGNSCSDFNGGCTHECVQE------------------- 1367
Query: 3090 MCASRKARCF-RIGY--CDDKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKGKYRCT 2920
A+C +G+ +D K C D+ CD + C HC +M +G +RC+
Sbjct: 1368 ---PFGAKCLCPLGFLLANDSKTCEDIDE--CDILGSCSQ-------HCYNM-RGSFRCS 1414
Score = 228 bits (581), Expect = 2e-57
Identities = 215/806 (26%), Positives = 322/806 (39%), Gaps = 30/806 (3%)
Frame = -1
Query: 3999 CIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKK 3820
C + F CG + C+ A CDG KDCS DD + C C + FKC + +
Sbjct: 28 CDSAHFRCG------SGHCIPADWRCDGTKDCS--DDADEIGCAVVTCQQGYFKCQSEGQ 79
Query: 3819 CIPLTSVCDKEKDCDDGSDE-LNCEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPE 3643
CIP + VCD+++DCDDGSDE +C ++C C NG +CIP E+ CD DCP+
Sbjct: 80 CIPSSWVCDQDQDCDDGSDERQDCSQSTCSSHQITCSNG----QCIPSEYRCDHVRDCPD 135
Query: 3642 GQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQCDGTLDCRDGSDEKGCKKEC---AIVCD 3472
G DE D + T EQ C +G C ++CD +DCRD SDE C + C C
Sbjct: 136 GADENDCQYP----TCEQLTCDNGACYNTSQKCDWKVDCRDSSDEINCTEICLHNEFSCG 191
Query: 3471 N-SCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKENRKCGGFACDGIVDCEDGSDEKG 3295
N C+ +CD C DGS DE AC CGG+ +
Sbjct: 192 NGECIPRAYVCDHDNDCQDGS--DEHAC--------NYPTCGGY-------------QFT 228
Query: 3294 CPDLECHLASNKSLICDGTIDCSSGKDENNCHNNGESNFFQCSM---------QTIKEWQ 3142
CP C ++ +CDG DC DE+ C +G + +CS + I ++
Sbjct: 229 CPSGRC---IYQNWVCDGEDDCKDNGDEDGC-ESGPHDVHKCSPREWSCPESGRCISIYK 284
Query: 3141 VCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDENP 2962
VCDG DC DE+ YC S LC + +C E P
Sbjct: 285 VCDGILDCPGREDENNTSTGK---------YC---------SMTLCSAL-NCQYQCHETP 325
Query: 2961 IHCKDMCKGKYRCTNG---RCIDVSARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMA 2791
C Y + C++ +C +G+C QKC
Sbjct: 326 YGGACFCPPGYIINHNDSRTCVEFD--------------------DCQIWGICDQKCESR 365
Query: 2790 FNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQVSVLRPVFNIK 2611
CHC GY + + A + +NG L + + +L N
Sbjct: 366 PGRHL-CHCEEGYILERGQYCKANDSFGEASIIFSNGRDLLIGDIHGRSFRILVESQN-- 422
Query: 2610 MNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGLITYDFM 2431
+ G+ F Y + R TV VDI + L S E+ A D++
Sbjct: 423 -RGVAVGVAFHYHLQRVFWTDTVQNKVFSVDINGLNIQEVLNVSVETPENLA----VDWV 477
Query: 2430 HNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIF-- 2257
+N +Y E ++ NR + + + V TLI + G +AVDP +F
Sbjct: 478 NNKIYLVE-TKVNRIDMVNLDGSYRV---------TLITENLGHPRGIAVDPTVGYLFFS 527
Query: 2256 -WTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDV 2080
W + + P++ A +DG K LV+ + P + LD ++R+YW+D
Sbjct: 528 DWESLSGEPKLERAFMDG-----------SNRKDLVKTKLGWPAGVTLDMISKRVYWVDS 576
Query: 2079 LKRTIETVSFDGRDRRT-VRKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGKTNK 1906
IETV++DG R+T V L P + + G ++ + ++ + +KFT
Sbjct: 577 RFDYIETVTYDGIQRKTVVHGGSLIPHPFGVSLFEGQVFFTDWTKMAVLKANKFT----- 631
Query: 1905 YVQKIREVSPRIQIRVA-HPAKHTVSHITHQ---KNPCQSDYCPSNTVCV----PDQDKN 1750
E +P++ + + P TV H Q NPC+ + VCV D D
Sbjct: 632 ------ETNPQVYYQASLRPYGVTVYHSLRQPYATNPCKDNNGGCEQVCVLSHRTDNDGL 685
Query: 1749 GILIPKCLCGPGRFFEVSTKKCMQLR 1672
G +C C G + + C+ ++
Sbjct: 686 GF---RCKCTFGFQLDTDERHCIAVQ 708
Score = 211 bits (538), Expect = 1e-52
Identities = 221/833 (26%), Positives = 323/833 (38%), Gaps = 57/833 (6%)
Frame = -1
Query: 4005 FPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDK 3826
FP Q VCG C Y +L C G EP +C F C +
Sbjct: 989 FPVPNFQRVCG---------CPYGMRLASNHLTCEGDPTNEPP---TEQCGLFSFPCKNG 1036
Query: 3825 KKCIPLTSVCDKEKDCDDGSDELNCEI--TSCKPDFFACFNGTAISKCIPKEFYCDGEDD 3652
+ C+P +CD DC D SDE C +C F C +G +CIP + CD +D
Sbjct: 1037 R-CVPNYYLCDGVDDCHDNSDEQLCGTLNNTCSSSAFTCGHG----ECIPAHWRCDKRND 1091
Query: 3651 CPEGQDEPDS-CFGIGECTHEQFQCTSGKCIPKRRQCDGTLDCRDGSDEKGCK-----KE 3490
C +G DE + C Q+ C + +CI K CD DC DGSDEK C +
Sbjct: 1092 CVDGSDEHNCPTHAPASCLDTQYTCDNHQCISKNWVCDTDNDCGDGSDEKNCNSTETCQP 1151
Query: 3489 CAIVCDNS-CVHADDLCDGKKKCNDGSDEDEEA--CVIKQLLEKENRKCGGFA--CDGIV 3325
C N C+ +CDG K C DGSDE C Q KC G CDG+
Sbjct: 1152 SQFNCPNHRCIDLSFVCDGDKDCVDGSDEVGCVLNCTASQFKCASGDKCIGVTNRCDGVF 1211
Query: 3324 DCEDGSDEKGCPDLE---CH----------LASNKSLICDGTIDCSSGKDENNC--HNNG 3190
DC D SDE GCP CH + CDG DC G DE+N
Sbjct: 1212 DCSDNSDEAGCPTRPPGMCHSDEFQCQEDGICIPNFWECDGHPDCLYGSDEHNACVPKTC 1271
Query: 3189 ESNFFQCSM-QTIKEWQVCDGRWDCADGLDESPEMCASRKARCFRIGY-CDDKKQCLDVS 3016
S++F C I +CD DC D DE C ++ RC + C C+++S
Sbjct: 1272 PSSYFHCDNGNCIHRAWLCDRDNDCGDMSDEKD--CPTQPFRCPSWQWQCLGHNICVNLS 1329
Query: 3015 TALCDGIRDCFDGSDENPI----HCKDMCKGKYRCTNGRCID----VSARXXXXXXXXXX 2860
+CDGI DC +G+DE+P+ C D G CT+ C+
Sbjct: 1330 V-VCDGIFDCPNGTDESPLCNGNSCSDFNGG---CTH-ECVQEPFGAKCLCPLGFLLAND 1384
Query: 2859 XXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECE-PLSKSAEMFITN 2683
EC G C+Q C+ + RC C GY ++D C+ S+S + + +
Sbjct: 1385 SKTCEDIDECDILGSCSQHCYN-MRGSFRCSCDTGYM-LESDGRTCKVTASESLLLLVAS 1442
Query: 2682 GNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKK 2503
N++ SV V NI +L+ G Y V + + R
Sbjct: 1443 QNKI-------IADSVTSQVHNI-YSLVENG------------SYIVAVDFDSISGRIF- 1481
Query: 2502 WSDGLIG-SWGEEESTAG-------------LITYDFMHNNVYFTESSEQNRGVLFDRQA 2365
WSD G +W ++ I D++ N+Y+T+ + +
Sbjct: 1482 WSDATQGKTWSAFQNGTDRRVVFDSSIILTETIAIDWVGRNLYWTDYALET--------- 1532
Query: 2364 NIYVAKAKDTSTRTLIVNSTGTINSLAVDPI--KRLIFWTTSAPVPRILSANLDGKPIAQ 2191
I V+K + LI + LA+DP + L+FW+ PRI A++DG
Sbjct: 1533 -IEVSKIDGSHRTVLISKNLTNPRGLALDPRMNEHLLFWSDWGHHPRIERASMDG----- 1586
Query: 2190 PFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFEL 2011
+V+ IF P + +D+ N LY++D ++ ++G RR V +L
Sbjct: 1587 ------SMRTVIVQDKIFWPCGLTIDYPNRLLYFMDSYLDYMDFCDYNGHHRRQVIASDL 1640
Query: 2010 -GDTPVTMDVLGGYIYLITR-QGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHT 1837
P + + +Y R + R +K+ G V + + + I HP+K
Sbjct: 1641 IIRHPYALTLFEDSVYWTDRATRRVMRANKWHGGNQSVV--MYNIQWPLGIVAVHPSKQ- 1697
Query: 1836 VSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQ 1678
+ NPC C + +C+ G C+C G C++
Sbjct: 1698 ----PNSVNPCAFSRC--SHLCL--LSSQGPHFYSCVCPSGWSLSPDLLNCLR 1742
Score = 153 bits (387), Expect = 5e-35
Identities = 105/320 (32%), Positives = 144/320 (44%), Gaps = 34/320 (10%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC---TCNENEFRCQ 6403
D+ D + C+ R C F C N CIP + +C+ NDC + +DE +C TC+ F+C
Sbjct: 3747 DNSDEENCAPRECTESEFRCVNQQCIPSRWICDHYNDCGDNSDERDCEMRTCHPEYFQCT 3806
Query: 6402 SGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDG 6223
SG C+ S+ +C+ DC DASDE CP R + + C CI P WKCDG
Sbjct: 3807 SGHCVHSELKCDGSADCLDASDEADCPTRFPD--GAYCQATMFEC-KNHVCIPPYWKCDG 3863
Query: 6222 TNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADG 6043
+DC DGSDE + + D C++ +F C R C+ H C+G DC DG
Sbjct: 3864 DDDCGDGSDE-ELHLCLDV---------PCNSPNRFRCDNNR-CIYSHEVCNGVDDCGDG 3912
Query: 6042 SD--EKNC---DAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGED------------- 5917
+D E++C K CT +E+ C + CIP + CD DC D D
Sbjct: 3913 TDETEEHCRKPTPKPCTEYEYKC-GNGHCIPHDNVCDDADDCGDWSDELGCNKGKERTCA 3971
Query: 5916 EHQCETECDS-KGGNATFRCT---------NHRCIPMAWRCDGTDDCMDNAKSL-GSDEV 5770
E+ CE C G CT C+ + C+ C + ++ GS E
Sbjct: 3972 ENICEQNCTQLNEGGFICSCTAGFETNVFDRTSCLDIN-ECEQFGTCPQHCRNTKGSYEC 4030
Query: 5769 DCAAGRTSF--HVPSRCADE 5716
CA G TS RCA E
Sbjct: 4031 VCADGFTSMSDRPGKRCAAE 4050
Score = 125 bits (314), Expect = 1e-26
Identities = 100/377 (26%), Positives = 171/377 (44%), Gaps = 20/377 (5%)
Frame = -1
Query: 5214 CPKANCSHFCIDRRDVGH--QCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTI 5041
C + CSH C+ H C C G+ LS + +C R+D + ++ V H + ++
Sbjct: 1704 CAFSRCSHLCLLSSQGPHFYSCVCPSGWSLSPDLLNCLRDD--QPFLITVRQHIIFGISL 1761
Query: 5040 DGHAKAT----LLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINS 4873
+ K+ ++ + NG+ +++D +YW + N I + V S
Sbjct: 1762 NPEVKSNDAMVPIAGIQNGLDVEFDDAEQYIYWVE-----NPGEIHRVKTDGTNRTVFAS 1816
Query: 4872 LPTKGID-GIAVDWLGRNIYYTDRNHDAIAVCDMRG--RFNRILLK--GTPLND--PRAI 4714
+ G +A+DW+ RN+Y T+ +I V + G R+ + L+ GT L P I
Sbjct: 1817 ISMVGPSMNLALDWISRNLYSTNPRTQSIEVLTLHGDIRYRKTLIANDGTALGVGFPIGI 1876
Query: 4713 VLDPLQALVFW----TDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYF 4546
+DP + ++W TD G A I NMDG++ + + + + +D Q+LY+
Sbjct: 1877 TVDPARGKLYWSDQGTDSGVPAKIASANMDGTSVKTLFTGN-LEHLECVTLDIEEQKLYW 1935
Query: 4545 GDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNR 4366
R I N DG+ R M+L + H + +AV + ++Y++D IERV K TG N
Sbjct: 1936 AVTGRGVIERGNVDGTDR-MILVHQLSHPWGIAVHDSFLYYTDEQYEVIERVDKATGAN- 1993
Query: 4365 KVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPAR-CDNLCIPANTPDLTTSSDNF 4189
K++++D G ++ H + S + CS C +C+P F
Sbjct: 1994 KIVLRDNVPNLRGLQVYHRRNAAESS-----NGCSNNMNACQQICLP-------VPGGLF 2041
Query: 4188 TCMCAQGFR--SEGRSC 4144
+C CA GF+ + RSC
Sbjct: 2042 SCACATGFKLNPDNRSC 2058
Score = 108 bits (269), Expect = 2e-21
Identities = 98/368 (26%), Positives = 160/368 (42%), Gaps = 16/368 (4%)
Frame = -1
Query: 5199 CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDT--IEAEILMVYGHRLKLFTIDGHAK 5026
C C+ C CA G+ L+ + + C ++ + + + + G L+L +
Sbjct: 2029 CQQICLPVPGGLFSCACATGFKLNPDNRSCSPYNSFIVVSMLSAIRGFSLEL-SDHSETM 2087
Query: 5025 ATLLSNLTNGVALDYDVKSDLVYWTD----VAHDGN----KAGITSMSNQPNTYRVINSL 4870
+ N + +D DV S +YW D VA D K +S+ N V + +
Sbjct: 2088 VPVAGQGRNALHVDVDVSSGFIYWCDFSSSVASDNAIRRIKPDGSSLMNI-----VTHGI 2142
Query: 4869 PTKGIDGIAVDWLGRNIYYTDR--NHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQ 4696
G+ GIAVDW+ N+Y+T+ + I V + + R+LLK T ++ PR IV+DP
Sbjct: 2143 GENGVRGIAVDWVAGNLYFTNAFVSETLIEVLRINTTYRRVLLKVT-VDMPRHIVVDPKN 2201
Query: 4695 ALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIAS 4516
+FW D+G I R +D +N V++ + + P LAVD +Y+ D D IA
Sbjct: 2202 RYLFWADYGQRPKIERSFLDCTNRTVLVSEGIVT-PRGLAVDRSDGYVYWVDDSLDIIAR 2260
Query: 4515 CNYDGSKRRMVLRGS-VRHIFALAVFEDYVYWSDWHNHTIERVHK-ITGTNRKVLIQDKQ 4342
+G ++ GS + + VFE+ + W D + I + K T +I+D
Sbjct: 2261 IRINGENSEVIRYGSRYPTPYGITVFENSIIWVDRNLKKIFQASKEPENTEPPTVIRDNI 2320
Query: 4341 YRPMGFKIVHPSLQSMGSLKTARHPC-SQPARCDNLCIPANTPDLTTSSDNFTCMCAQG- 4168
I +Q + +PC C +LC P L T C CA G
Sbjct: 2321 NWLRDVTIFDKQVQPRSPAEVNNNPCLENNGGCSHLCFA--LPGLHTPK----CDCAFGT 2374
Query: 4167 FRSEGRSC 4144
+S+G++C
Sbjct: 2375 LQSDGKNC 2382
Score = 103 bits (256), Expect = 7e-20
Identities = 105/385 (27%), Positives = 143/385 (36%), Gaps = 58/385 (15%)
Frame = -1
Query: 6012 CTSFEFSCESSKKCIP----LEQKCDGRRDCPDGEDEHQCETECDSKGGNATFRCTNHRC 5845
C F C S C P E +C + + C + + G ++F C+N RC
Sbjct: 2655 CEQFNGGC--SHICAPGPNGAECQCPHEGNWYLANNRKHCIVDNGERCGASSFTCSNGRC 2712
Query: 5844 IPMAWRCDGTDDCMDNAKSLGSDEVD-CAAGRTSFHVPSRCADETCVVACELTAVLCDGI 5668
I W+CD +DC D GSDE++ A T CA+ CV + CD
Sbjct: 2713 ISEEWKCDNDNDCGD-----GSDEMESVCALHTCSPTAFTCANGRCV----QYSYRCDYY 2763
Query: 5667 QDCSDGFDEKNCASLDRQCK-PNEWMCDSGQCIDSGRLCDASVDCVDGSDEWVEICSLSE 5491
DC DG DE C L R C E+MC++ +CI +C+ +C D + + C
Sbjct: 2764 NDCGDGSDEAGC--LFRDCNATTEFMCNNRRCIPREFICNGVDNCHDNNTSDEKNC---- 2817
Query: 5490 PPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQ--------CDNPQGNCSST 5335
P R C SG++ N I C+ LCDG DC DE C + + C+S
Sbjct: 2818 -PDRTCQSGYT-KCHNSNI-CIPRVYLCDGDNDCGDNSDENPTYCTTHTCSSSEFQCASG 2874
Query: 5334 RNSCDQTWNCQRH-----AGFESCSCDDGYHLSPYDKKTC-------------------- 5230
R Q W C + A E SC D+ C
Sbjct: 2875 R-CIPQHWYCDQETDCFDASDEPASCGHSERTCLADEFKCDGGRCIPSEWICDGDNDCGD 2933
Query: 5229 ----LRSPSCPKANCS---HFCIDRRDVGHQCF-----------CAPGYILSENQKDCRR 5104
+ C NCS C++ R +C C GY ENQ +C R
Sbjct: 2934 MSDEDKRHQCQNQNCSDSEFLCVNDRPPDRRCIPQSWVCDGDVDCTDGY--DENQ-NCTR 2990
Query: 5103 NDTIEAEILMVYGHRL-KLFTIDGH 5032
E E YG + K+F D H
Sbjct: 2991 RTCSENEFTCGYGLCIPKIFRCDRH 3015
Score = 98.2 bits (243), Expect = 2e-18
Identities = 191/868 (22%), Positives = 314/868 (36%), Gaps = 65/868 (7%)
Frame = -1
Query: 2820 GVCAQKCW-MAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQ 2644
G C+ C+ + HT +C CA + ++D C +++ +F + N L + L+
Sbjct: 2351 GGCSHLCFALPGLHTPKCDCA--FGTLQSDGKNCAISTENFLIFALS-NSLRSLHLDPEN 2407
Query: 2643 VSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGN-SRVDIRSKKWSDGLIGSWGEE 2467
S N++ ++ D D T G+G S + S + +I S
Sbjct: 2408 HSPPFQTINVERTVMSLDYDSVSDRIYFTQNLASGVGQISYATLSSGIHTPTVIASG--- 2464
Query: 2466 ESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSL 2287
TA I +D++ +Y+++ Q + + A+D S RT+I ++
Sbjct: 2465 IGTADGIAFDWITRRIYYSDYLNQ-----------MINSMAEDGSNRTVIARVPKP-RAI 2512
Query: 2286 AVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFS 2107
+DP + ++W +I A L G F+ +V ++ P+ + LD+
Sbjct: 2513 VLDPCQGYLYWADWDTHAKIERATLGGN-----FRV------PIVNSSLVMPSGLTLDYE 2561
Query: 2106 NERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIY---LITRQGSIHR 1936
+ LYW+D + IE + G DR + + +T+ G YIY L T++ I+R
Sbjct: 2562 EDLLYWVDASLQRIERSTLTGVDREVIVNAAVHAFGLTL--YGQYIYWTDLYTQR--IYR 2617
Query: 1935 MHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYC---PSNTVCVP 1765
+K+ G + PR V K ++ Q N S C P+ C
Sbjct: 2618 ANKYDGSGQIAMTTNLLSQPRGINTVVKNQKQQCNNPCEQFNGGCSHICAPGPNGAECQC 2677
Query: 1764 DQDKNGILI---PKCLCGPGR-----FFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCS 1609
+ N L C+ G F S +C+ K + CGD + C+
Sbjct: 2678 PHEGNWYLANNRKHCIVDNGERCGASSFTCSNGRCISEEWKCDNDNDCGDGSDEMESVCA 2737
Query: 1608 PQKTC-----VCPPG---FYGRQCE-INECSETCWNGETCAVQEFGSTTNVVCHCPSNYT 1456
TC C G Y +C+ N+C + + C ++ +TT +C N
Sbjct: 2738 -LHTCSPTAFTCANGRCVQYSYRCDYYNDCGDGS-DEAGCLFRDCNATTEFMC----NNR 2791
Query: 1455 QSSCATNVCEGV--CGPRGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHKADAKVCY 1282
+ +C GV C + DE +C + C G+T H ++ +C
Sbjct: 2792 RCIPREFICNGVDNCHDNNT-------SDEKNCPDRT---CQSGYTKCH-----NSNICI 2836
Query: 1281 GHCFSGGACDGEGPLNLRCSCGDGLTGNRCQNCVGHECLNGGFCSYANSNRSLP-HCICP 1105
+ CDG+ CGD N C H C + F S R +P H C
Sbjct: 2837 PRVY---LCDGDN------DCGDNSDENPTY-CTTHTCSSSEF--QCASGRCIPQHWYCD 2884
Query: 1104 SGFTGDHCEEYLCKDACPFGSKCTY-DITKPMDPITCSCEQNAAAH-----NTDCSPICQ 943
+E C DA + C + + T D C + + + DC +
Sbjct: 2885 --------QETDCFDASDEPASCGHSERTCLADEFKCDGGRCIPSEWICDGDNDCGDMSD 2936
Query: 942 KQPNWCHNGGRCLDTP-----GYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSKCTITNGT 778
+ C D+ P +C+P+ CD V C D N CT +
Sbjct: 2937 EDKRHQCQNQNCSDSEFLCVNDRPPDRRCIPQ--SWVCDGDVDCTDGYDENQNCTRRTCS 2994
Query: 777 HFECDCKPGF---KGLRCEQETKCSECSNEAKCIKKP--------------SGTVICQCP 649
E C G K RC++ C + S+E C+ + S T +C
Sbjct: 2995 ENEFTCGYGLCIPKIFRCDRHNDCGDYSDERGCLYQTCQQNQFTCQNGRCISKTFVCDED 3054
Query: 648 QGLGGEYCEKI-----TATSC--HQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCS 490
G E + +C H+ +C N G C++ N CL + KG C
Sbjct: 3055 NDCGDGSDELMHLCHTPEPTCPPHEFKCDN-GRCIEMMKLCNHLD-DCLDNSDEKG--CG 3110
Query: 489 SNACENFCLH--DGNCTLDEYFEPQCEC 412
N C + + D NCT D C C
Sbjct: 3111 INECHDPSISGCDHNCT-DTLTSFYCSC 3137
Score = 93.2 bits (230), Expect = 8e-17
Identities = 157/724 (21%), Positives = 252/724 (34%), Gaps = 40/724 (5%)
Frame = -1
Query: 2448 ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIK 2269
+ +D++ N+Y+T+S ++ I V + D + RT +V S+ V P
Sbjct: 789 LAFDWISKNLYWTDSHYKS----------ISVMRLADKTRRT-VVQYLNNPRSVVVHPFA 837
Query: 2268 RLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYW 2089
+F+T +I+ A DG + T + P + +D++ RLYW
Sbjct: 838 GYLFFTDWFRPAKIMRAWSDGSHLLPVINT-----------TLGWPNGLAIDWAASRLYW 886
Query: 2088 IDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTG-- 1918
+D IE +FDG DRR + E P + + G +++ R G+I R+ K G
Sbjct: 887 VDAYFDKIEHSTFDGLDRRRLGHIEQMTHPFGLAIFGEHLFFTDWRLGAIIRVRKADGGE 946
Query: 1917 -----KTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDK 1753
Y+ ++ IQ + + TH C S +C VP+ +
Sbjct: 947 MTVIRSGIAYILHLKSYDVNIQ-----TGSNACNQPTHPNGDC-SHFC----FPVPNFQR 996
Query: 1752 NGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCSPQKTCVCPPGFY 1573
C C G + C + QCG + P K C P +Y
Sbjct: 997 ------VCGCPYGMRLASNHLTCEGDPTNEPPTEQCGLF-------SFPCKNGRCVPNYY 1043
Query: 1572 GRQCE-INECSETCWNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVC---EGVCGPRG 1405
C+ +++C + + ++ T N C + + +C C C R
Sbjct: 1044 --LCDGVDDCHDN-------SDEQLCGTLNNTC----SSSAFTCGHGECIPAHWRCDKRN 1090
Query: 1404 SCKTVPCPKDEPHCRSYSFCEC-DKGWTGPHCRHKADAKVCYGH-CFS-GGACDGEGPLN 1234
C DE +C +++ C D +T C H C S CD +
Sbjct: 1091 DCVD---GSDEHNCPTHAPASCLDTQYT------------CDNHQCISKNWVCDTDN--- 1132
Query: 1233 LRCSCGDGLTGNRCQ----------NCVGHECLNGGFCSYANSNRSLPHCICPSGFTGDH 1084
CGDG C NC H C++ F + + C+ S G
Sbjct: 1133 ---DCGDGSDEKNCNSTETCQPSQFNCPNHRCIDLSFVCDGDKD-----CVDGSDEVGCV 1184
Query: 1083 CEEYLCKDACPFGSKCTYDITKPMDPI-TCSCEQNAAAHNTDCSPICQKQPNWCHNGGRC 907
+ C G KC +T D + CS + A T +C C G C
Sbjct: 1185 LNCTASQFKCASGDKC-IGVTNRCDGVFDCSDNSDEAGCPTRPPGMCHSDEFQCQEDGIC 1243
Query: 906 L----DTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSKCTITNGTHFECD---CKPGF 748
+ + G+P CL VP C ++F CD C
Sbjct: 1244 IPNFWECDGHP---DCLYGSDEHNACVPKTCP-------------SSYFHCDNGNCI--H 1285
Query: 747 KGLRCEQETKCSECSNEAKCIKKPSGTVICQCP----QGLGGEYCEKITATSCHQLECKN 580
+ C+++ C + S+E C +P +CP Q LG C ++ +C N
Sbjct: 1286 RAWLCDRDNDCGDMSDEKDCPTQP-----FRCPSWQWQCLGHNICVNLSVVCDGIFDCPN 1340
Query: 579 GGYCLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCLHDGNCT---LDEYFEPQCECY 409
G SP LC+ N+C +F +G CT + E F +C C
Sbjct: 1341 G----------TDESP-----------LCNGNSCSDF---NGGCTHECVQEPFGAKCLCP 1376
Query: 408 QAFI 397
F+
Sbjct: 1377 LGFL 1380
Score = 79.7 bits (195), Expect = 9e-13
Identities = 37/95 (38%), Positives = 48/95 (49%), Gaps = 7/95 (7%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADE-------SNCTCNENE 6415
D D + C + C+ F C NG CI + VC+ NDC + +DE TC +E
Sbjct: 3020 DYSDERGCLYQTCQQNQFTCQNGRCISKTFVCDEDNDCGDGSDELMHLCHTPEPTCPPHE 3079
Query: 6414 FRCQSGACIPSKARCNHMQDCNDASDEIGCPFRNC 6310
F+C +G CI CNH+ DC D SDE GC C
Sbjct: 3080 FKCDNGRCIEMMKLCNHLDDCLDNSDEKGCGINEC 3114
Score = 60.1 bits (144), Expect = 7e-07
Identities = 38/142 (26%), Positives = 62/142 (42%), Gaps = 10/142 (7%)
Frame = -1
Query: 6579 MFDDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCTCNENEFRCQS 6400
++ ++ C + C YF+C NG CI +C+R NDC + +DE +C FRC S
Sbjct: 1257 LYGSDEHNACVPKTCPSSYFHCDNGNCIHRAWLCDRDNDCGDMSDEKDCP--TQPFRCPS 1314
Query: 6399 --------GACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIH 6244
C+ C+ + DC + +DE P N ++ ++F N T +C+
Sbjct: 1315 WQWQCLGHNICVNLSVVCDGIFDCPNGTDE--SPLCNGNSCSDF------NGGCTHECVQ 1366
Query: 6243 PSW--KCDGTNDCYDGSDEKDC 6184
+ KC +D K C
Sbjct: 1367 EPFGAKCLCPLGFLLANDSKTC 1388
Score = 54.7 bits (130), Expect = 3e-05
Identities = 62/293 (21%), Positives = 107/293 (36%), Gaps = 1/293 (0%)
Frame = -1
Query: 2829 HHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLEN 2650
++ C Q C C CA G+ + D C P + + + + R + L +
Sbjct: 2024 NNMNACQQICLPVPGGLFSCACATGF-KLNPDNRSCSPYNSFIVVSMLSAIRGFSLELSD 2082
Query: 2649 SQVSVLRPVFNIKMNLIPGGIDFGYD-VFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWG 2473
+++ PV N + +D ++ +V N+ I+ S I + G
Sbjct: 2083 HSETMV-PVAGQGRNALHVDVDVSSGFIYWCDFSSSVASDNAIRRIKPDGSSLMNIVTHG 2141
Query: 2472 EEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTIN 2293
E+ I D++ N+YFT + F + I V + T R L+ +
Sbjct: 2142 IGENGVRGIAVDWVAGNLYFTNA--------FVSETLIEVLRINTTYRRVLLKVTVDMPR 2193
Query: 2292 SLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLD 2113
+ VDP R +FW P+I + LD LV I P + +D
Sbjct: 2194 HIVVDPKNRYLFWADYGQRPKIERSFLD-----------CTNRTVLVSEGIVTPRGLAVD 2242
Query: 2112 FSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITR 1954
S+ +YW+D I + +G + +R TP + V I + R
Sbjct: 2243 RSDGYVYWVDDSLDIIARIRINGENSEVIRYGSRYPTPYGITVFENSIIWVDR 2295
Score = 46.2 bits (108), Expect = 0.011
Identities = 86/356 (24%), Positives = 115/356 (32%), Gaps = 40/356 (11%)
Frame = -1
Query: 1650 QCGDYFCYNNAGCSPQKTCV-----CPPGFYGRQ-CEINECSE---TCWNGETCAVQEFG 1498
Q G + C + C P C G RQ C + CS TC NG+ C E+
Sbjct: 68 QQGYFKCQSEGQCIPSSWVCDQDQDCDDGSDERQDCSQSTCSSHQITCSNGQ-CIPSEY- 125
Query: 1497 STTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSYSFCECDKGWTGP 1318
+ V CP ++ C CE + G+C + +CD W
Sbjct: 126 -RCDHVRDCPDGADENDCQYPTCEQLTCDNGACYN-------------TSQKCD--WK-V 168
Query: 1317 HCRHKADAKVCYGHCFSGGACDGEGPLNLRC-------SCGDGLTGNRCQ--NCVGHE-C 1168
CR +D C C G G R C DG + C C G++
Sbjct: 169 DCRDSSDEINCTEICLHNEFSCGNGECIPRAYVCDHDNDCQDGSDEHACNYPTCGGYQFT 228
Query: 1167 LNGGFCSYANSNRSLPHCICPSGFTGDHCEE-----YLCKD---ACPFGSKCTYDITKPM 1012
G C Y N C D CE + C +CP +C I K
Sbjct: 229 CPSGRCIYQNWVCD-GEDDCKDNGDEDGCESGPHDVHKCSPREWSCPESGRC-ISIYKVC 286
Query: 1011 DPITCSCEQNAAAHNTD---------CSPI-CQKQPNWCHNGGRCLDTPGYPGKCKCLPR 862
D I C +NT CS + CQ Q + GG C PGY +
Sbjct: 287 DGI-LDCPGREDENNTSTGKYCSMTLCSALNCQYQCHETPYGGACFCPPGY-----IINH 340
Query: 861 FAGPRCDVPVQCDDYCTNNSKCTITNGTHFECDCKPGF---KGLRCEQETKCSECS 703
C C + + KC G H C C+ G+ +G C+ E S
Sbjct: 341 NDSRTCVEFDDCQIWGICDQKCESRPGRHL-CHCEEGYILERGQYCKANDSFGEAS 395
Score = 40.4 bits (93), Expect = 0.59
Identities = 17/40 (42%), Positives = 24/40 (59%)
Frame = -1
Query: 1170 CLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDACP 1051
C++GG C + ++ LP C CPSG+TG +CE K P
Sbjct: 4383 CMHGGNCYFDETD--LPKCKCPSGYTGKYCEMAFSKGISP 4420
Score = 38.5 bits (88), Expect = 2.2
Identities = 24/83 (28%), Positives = 36/83 (42%), Gaps = 1/83 (1%)
Frame = -1
Query: 627 CEKITATSCHQLECKNGGY-CLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCLHDGN 451
C++I + C + GGY C P S+ T C + + C C+H GN
Sbjct: 4334 CKQICSHLCL---LRPGGYSCACPQGSSFIEGSTTECDAAIELPINLPPPCR--CMHGGN 4388
Query: 450 CTLDEYFEPQCECYQAFIGDRCQ 382
C DE P+C+C + G C+
Sbjct: 4389 CYFDETDLPKCKCPSGYTGKYCE 4411
>gi|32816597|gb|AAP88586.1| glycoprotein receptor gp330/megalin
precursor [Homo sapiens]
Length = 4655
Score = 727 bits (1877), Expect = 0.0
Identities = 543/1819 (29%), Positives = 801/1819 (43%), Gaps = 147/1819 (8%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCT---CNEN-EFRCQ 6403
DE C+ C P F C NG C+ C+ NDC + +DE+ C CN EF C
Sbjct: 2730 DEMESVCALHTCSPTAFTCANGRCVQYSYRCDYYNDCGDGSDEAGCLFRDCNATTEFMCN 2789
Query: 6402 SGACIPSKARCNHMQDCND--ASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKC 6229
+ CIP + CN + +C+D SDE CP R C + G C ++ CI + C
Sbjct: 2790 NRRCIPREFICNGVDNCHDNNTSDEKNCPDRTCQS-------GYTKCHNSNICIPRVYLC 2842
Query: 6228 DGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCA 6049
DG NDC D SDE + +C + ++F C + R C+P+HW CD + DC
Sbjct: 2843 DGDNDCGDNSDENPTYC----------TTHTCSS-SEFQCASGR-CIPQHWYCDQETDCF 2890
Query: 6048 DGSDEK-NC--DAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDE---HQCETECDS 5887
D SDE +C + C + EF C+ + CIP E CDG DC D DE HQC+ + S
Sbjct: 2891 DASDEPASCGHSERTCLADEFKCDGGR-CIPSEWICDGDNDCGDMSDEDKRHQCQNQNCS 2949
Query: 5886 KGGNATFRCTN-----HRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCA 5722
++ F C N RCIP +W CDG DC D G DE RT C
Sbjct: 2950 ---DSEFLCVNDRPPDRRCIPQSWVCDGDVDCTD-----GYDENQNCTRRTCSENEFTCG 3001
Query: 5721 DETCVVACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASV 5542
C+ CD DC D DE+ C L + C+ N++ C +G+CI +CD
Sbjct: 3002 YGLCIPKI----FRCDRHNDCGDYSDERGC--LYQTCQQNQFTCQNGRCISKTFVCDEDN 3055
Query: 5541 DCVDGSDEWVEICSLSEPPRRGCPSG-WSCLLTNGTIGCLQEQQLCDGRRDCMSGIDE-- 5371
DC DGSDE + +C EP CP + C NG C++ +LC+ DC+ DE
Sbjct: 3056 DCGDGSDELMHLCHTPEPT---CPPHEFKC--DNGR--CIEMMKLCNHLDDCLDNSDEKG 3108
Query: 5370 ----QCDNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKA 5203
+C +P + + CD NC CSC GY L DK+TC+ C +
Sbjct: 3109 CGINECHDP------SISGCDH--NCTDTLTSFYCSCRPGYKLMS-DKRTCVDIDECTEM 3159
Query: 5202 N--CSHFCIDRRDVG-HQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGH 5032
CS C +G + C CAPGY+ + K CR+N IE ++ + L+ TIDG+
Sbjct: 3160 PFVCSQKC--ENVIGSYICKCAPGYLREPDGKTCRQNSNIEPYLIFSNRYYLRNLTIDGY 3217
Query: 5031 AKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINS-LPTKGI 4855
+ +L L N VALD+D +YW D + N+ N +IN LP
Sbjct: 3218 FYSLILEGLDNVVALDFDRVEKRLYWIDTQRQVIER---MFLNKTNKETIINHRLPAA-- 3272
Query: 4854 DGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTP-------LNDPRAIVLDPLQ 4696
+ +AVDW+ R +Y+ D D + V D+ G R+L + ++PR + L P
Sbjct: 3273 ESLAVDWVSRKLYWLDARLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLALHPQY 3332
Query: 4695 ALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIAS 4516
++W DWG A+IGR+ MDG+N+ VI+ + + WPN + +D LY+ DAH YI
Sbjct: 3333 GYLYWADWGHRAYIGRVGMDGTNKSVIISTK-LEWPNGITIDYTNDLLYWADAHLGYIEY 3391
Query: 4515 CNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYR 4336
+ +G R V G++ H FA+ +FED +YW+DW+ T+E+ +K G+NR+ L+ + +R
Sbjct: 3392 SDLEGHHRHTVYDGALPHPFAITIFEDTIYWTDWNTRTVEKGNKYDGSNRQTLV-NTTHR 3450
Query: 4335 PMGFKIVHPSLQSMGSLKTARHPC-SQPARCDNLCIPANTPDLTTSSDNFTCMCAQGFR- 4162
P + HP Q + S +PC + C +LC+ + FTC C FR
Sbjct: 3451 PFDIHVYHPYRQPIVS-----NPCGTNNGGCSHLCL------IKPGGKGFTCECPDDFRT 3499
Query: 4161 ---SEGRSCVSECKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIA 3991
S C+ C F+C KCI WW+ +CP C
Sbjct: 3500 LQLSGSTYCMPMCSSTQFLCANNEKCIPIWWKCDGQKDCSDGSDEL----ALCPQRFCRL 3555
Query: 3990 GQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIP 3811
GQF C + C LC+ ++C G DE+ CEN C +++C + K+CIP
Sbjct: 3556 GQFQC------SDGNCTSPQTLCNAHQNCPDGSDEDRLLCENHHCDSNEWQCAN-KRCIP 3608
Query: 3810 LTSVCDKEKDCDDGSDE--LNCEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQ 3637
+ CD DC+D SDE +C +C+P F C NG +CIP+ + CD ++DC +
Sbjct: 3609 ESWQCDTFNDCEDNSDEDSSHCASRTCRPGQFRCANG----RCIPQAWKCDVDNDCGDHS 3664
Query: 3636 DEP-DSCFGIGEC--THEQFQC-TSGKCIPKRRQCDGTLDCRDGSDEKGC-KKECAIVCD 3472
DEP + C +F C T+ +CIPK C+G DCRD SDE+GC ++ C V D
Sbjct: 3665 DEPIEECMSSAHLCDNFTEFSCKTNYRCIPKWAVCNGVDDCRDNSDEQGCEERTCHPVGD 3724
Query: 3471 -----NSCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKE----NRKC--GGFACDGIV 3325
+ C+ CDG+ C D S DEE C ++ E E N++C + CD
Sbjct: 3725 FRCKNHHCIPLRWQCDGQNDCGDNS--DEENCAPRECTESEFRCVNQQCIPSRWICDHYN 3782
Query: 3324 DCEDGSDEKGCPDLECH---------LASNKSLICDGTIDCSSGKDENNCHNN------G 3190
DC D SDE+ C CH + L CDG+ DC DE +C
Sbjct: 3783 DCGDNSDERDCEMRTCHPEYFQCTSGHCVHSELKCDGSADCLDASDEADCPTRFPDGAYC 3842
Query: 3189 ESNFFQCSMQT-IKEWQVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCLDVST 3013
++ F+C I + CDG DC DG DE +C CD+ + C+ S
Sbjct: 3843 QATMFECKNHVCIPPYWKCDGDDDCGDGSDEELHLCLDVPCNSPNRFRCDNNR-CI-YSH 3900
Query: 3012 ALCDGIRDCFDGSDENPIHC-----KDMCKGKYRCTNGRCI-------DVSARXXXXXXX 2869
+C+G+ DC DG+DE HC K + +Y+C NG CI D
Sbjct: 3901 EVCNGVDDCGDGTDETEEHCRKPTPKPCTEYEYKCGNGHCIPHDNVCDDADDCGDWSDEL 3960
Query: 2868 XXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFI 2689
AE +C Q C C C G+ D C +++ E F
Sbjct: 3961 GCNKGKERTCAE----NICEQNCTQLNEGGFICSCTAGFETNVFDRTSCLDINE-CEQFG 4015
Query: 2688 TNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRS 2509
T H + + S V F M+ PG + L+ + + ++ S
Sbjct: 4016 TCPQ--HCRNTKGSYECVCADGFT-SMSDRPGK-RCAAEGSSPLLLLPDNVRIRKYNLSS 4071
Query: 2508 KKWSDGLIGSWGEEESTAGLITYDFMHNN-----VYFTESSEQNR--------------- 2389
+++S+ L ++E + YD+ + VY+T E +R
Sbjct: 4072 ERFSEYL-----QDEEYIQAVDYDWDPEDIGLSVVYYTVRGEGSRFGAIKRAYIPNFESG 4126
Query: 2388 -------------------GVLFD-----------RQANIYVAKAKDTSTRTLIVNSTGT 2299
G+ D + I VAK + LI
Sbjct: 4127 RNNLVQEVDLKLKYVMQPDGIAVDWVGRHIYWSDVKNKRIEVAKLDGRYRKWLISTDLDQ 4186
Query: 2298 INSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMV 2119
++AV+P L+FWT P++ SA ++G + LV ++ PT +
Sbjct: 4187 PAAIAVNPKLGLMFWTDWGKEPKLESAWMNG-----------EDRNILVFEDLGWPTGLS 4235
Query: 2118 LDF-SNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITRQ-GS 1945
+D+ +N+R+YW D + IET+ +DG DRR + K + P ++D+ +Y I+++ G
Sbjct: 4236 IDYLNNDRIYWSDFKEDVIETIKYDGTDRRVIAKEAM--NPYSLDIFEDQLYWISKEKGE 4293
Query: 1944 IHRMHKFTGKTNKYVQKIREVSPRI-QIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCV 1768
+ + +KF G+ K +K V+P + Q+R+ H ++ S K C S C
Sbjct: 4294 VWKQNKF-GQGKK--EKTLVVNPWLTQVRIFHQLRYNKSVPNLCKQIC-SHLC------- 4342
Query: 1767 PDQDKNGILIP---KCLCGPG-RFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCSPQK 1600
+L P C C G F E ST +C E C + C +
Sbjct: 4343 -------LLRPGGYSCACPQGSSFIEGSTTECDAAIELPINLPP--PCRCMHGGNCYFDE 4393
Query: 1599 T----CVCPPGFYGRQCEI 1555
T C CP G+ G+ CE+
Sbjct: 4394 TDLPKCKCPSGYTGKYCEM 4412
Score = 372 bits (956), Expect = e-101
Identities = 261/820 (31%), Positives = 382/820 (45%), Gaps = 17/820 (2%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC-----TCNENEFR 6409
+ + T T C F C NG C+P +C+ ++DC + +DE C TC+ + F
Sbjct: 1014 EGDPTNEPPTEQCGLFSFPCKNGRCVPNYYLCDGVDDCHDNSDEQLCGTLNNTCSSSAFT 1073
Query: 6408 CQSGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKC 6229
C G CIP+ RC+ DC D SDE CP ++ + T QCI +W C
Sbjct: 1074 CGHGECIPAHWRCDKRNDCVDGSDEHNCPTHAPASCLDTQYT-----CDNHQCISKNWVC 1128
Query: 6228 DGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCA 6049
D NDC DGSDEK+C ++ +C +QF C C+ + CDG DC
Sbjct: 1129 DTDNDCGDGSDEKNC-----------NSTETCQ-PSQFNC-PNHRCIDLSFVCDGDKDCV 1175
Query: 6048 DGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNAT 5869
DGSDE C CT+ +F C S KCI + +CDG DC D DE C T +
Sbjct: 1176 DGSDEVGC-VLNCTASQFKCASGDKCIGVTNRCDGVFDCSDNSDEAGCPTRPPGMCHSDE 1234
Query: 5868 FRCTNHR-CIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACEL 5692
F+C CIP W CDG DC+ GSDE + +T C + C+
Sbjct: 1235 FQCQEDGICIPNFWECDGHPDCL-----YGSDEHNACVPKTCPSSYFHCDNGNCI----H 1285
Query: 5691 TAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMC-DSGQCIDSGRLCDASVDCVDGSDEW 5515
A LCD DC D DEK+C + +C +W C C++ +CD DC +G+DE
Sbjct: 1286 RAWLCDRDNDCGDMSDEKDCPTQPFRCPSWQWQCLGHNICVNLSVVCDGIFDCPNGTDE- 1344
Query: 5514 VEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSST 5335
+C +G SC NG GC E C+ + N C
Sbjct: 1345 SPLC-----------NGNSCSDFNG--GCTHECVQEPFGAKCLCPLGFLLANDSKTCEDI 1391
Query: 5334 RNSCDQTWNCQRHA----GFESCSCDDGYHLSPYDKKTCLRSPSCPKANCSHFCIDRRDV 5167
+ CD +C +H G CSCD GY L D +TC K S +
Sbjct: 1392 -DECDILGSCSQHCYNMRGSFRCSCDTGYMLES-DGRTC-------KVTASESLL----- 1437
Query: 5166 GHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLTNGVAL 4987
+ S+N+ D++ +++ +Y +L+ N + VA+
Sbjct: 1438 --------LLVASQNKIIA---DSVTSQVHNIY---------------SLVENGSYIVAV 1471
Query: 4986 DYDVKSDLVYWTDVAHDGNKAGITSMSNQPNT-YRVINSLPTKGIDGIAVDWLGRNIYYT 4810
D+D S ++W+D G T + Q T RV+ + IA+DW+GRN+Y+T
Sbjct: 1472 DFDSISGRIFWSDATQ-----GKTWSAFQNGTDRRVVFDSSIILTETIAIDWVGRNLYWT 1526
Query: 4809 DRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPL--QALVFWTDWGASAHIGRMNMD 4636
D + I V + G +L+ L +PR + LDP + L+FW+DWG I R +MD
Sbjct: 1527 DYALETIEVSKIDGSHRTVLISKN-LTNPRGLALDPRMNEHLLFWSDWGHHPRIERASMD 1585
Query: 4635 GSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGS--VRH 4462
GS VI+QD+ I WP L +D P + LYF D++ DY+ C+Y+G RR V+ +RH
Sbjct: 1586 GSMRTVIVQDK-IFWPCGLTIDYPNRLLYFMDSYLDYMDFCDYNGHHRRQVIASDLIIRH 1644
Query: 4461 IFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLK 4282
+AL +FED VYW+D + R +K G N+ V++ + Q+ P+G VHPS Q
Sbjct: 1645 PYALTLFEDSVYWTDRATRRVMRANKWHGGNQSVVMYNIQW-PLGIVAVHPSKQ-----P 1698
Query: 4281 TARHPCSQPARCDNLCIPANTPDLTTSSDNF-TCMCAQGF 4165
+ +PC+ +RC +LC+ L++ +F +C+C G+
Sbjct: 1699 NSVNPCAF-SRCSHLCL------LSSQGPHFYSCVCPSGW 1731
Score = 349 bits (895), Expect = 6e-94
Identities = 427/1791 (23%), Positives = 678/1791 (37%), Gaps = 184/1791 (10%)
Frame = -1
Query: 5247 YDKKTCLRSPS------CPKAN--CSHFCIDRRDVGH-QCFCAPGYILSENQKDCRRNDT 5095
+DK+ RSP+ C + N CSH C + +C CA G + S+ +N
Sbjct: 2329 FDKQVQPRSPAEVNNNPCLENNGGCSHLCFALPGLHTPKCDCAFGTLQSDG-----KNCA 2383
Query: 5094 IEAEILMVYGHRLKLFTI----DGHAKATLLSNLTNGV-ALDYDVKSDLVYWT-DVAHDG 4933
I E +++ L ++ + H+ N+ V +LDYD SD +Y+T ++A
Sbjct: 2384 ISTENFLIFALSNSLRSLHLDPENHSPPFQTINVERTVMSLDYDSVSDRIYFTQNLASGV 2443
Query: 4932 NKAGITSMSNQPNTYRVINSLPTKGI---DGIAVDWLGRNIYYTDRNHDAIAVCDMRGRF 4762
+ ++S+ +T VI S GI DGIA DW+ R IYY+D + I G
Sbjct: 2444 GQISYATLSSGIHTPTVIAS----GIGTADGIAFDWITRRIYYSDYLNQMINSMAEDGS- 2498
Query: 4761 NRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNA 4582
NR ++ P PRAIVLDP Q ++W DW A I R + G N +V + + ++ P+
Sbjct: 2499 NRTVIARVP--KPRAIVLDPCQGYLYWADWDTHAKIERATL-GGNFRVPIVNSSLVMPSG 2555
Query: 4581 LAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHT 4402
L +D LY+ DA I G R +++ +V H F L ++ Y+YW+D +
Sbjct: 2556 LTLDYEEDLLYWVDASLQRIERSTLTGVDREVIVNAAV-HAFGLTLYGQYIYWTDLYTQR 2614
Query: 4401 IERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPAR-----CDNL 4237
I R +K G+ + + + +P G V +K + C+ P C ++
Sbjct: 2615 IYRANKYDGSGQIAMTTNLLSQPRGINTV---------VKNQKQQCNNPCEQFNGGCSHI 2665
Query: 4236 CIPANTPDLTTSSDNFTCMCAQG----FRSEGRSCVSE----CKPNDFVCTKTYKCISSW 4081
C P + C C + + C+ + C + F C+ +CIS
Sbjct: 2666 CAPG--------PNGAECQCPHEGNWYLANNRKHCIVDNGERCGASSFTCSNG-RCISEE 2716
Query: 4080 WRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCS 3901
W+ +E VC C F C A +C+ S CD DC
Sbjct: 2717 WKCDNDNDCGDGSDE---MESVCALHTCSPTAFTC------ANGRCVQYSYRCDYYNDCG 2767
Query: 3900 GGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDG--SDELNCEITSCKPD 3727
G DE + T +F C +++ CIP +C+ +C D SDE NC +C+
Sbjct: 2768 DGSDEAGCLFRDCNAT-TEFMCNNRR-CIPREFICNGVDNCHDNNTSDEKNCPDRTCQSG 2825
Query: 3726 FFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQ 3547
+ C N CIP+ + CDG++DC + DE + C+ +FQC SG+CIP+
Sbjct: 2826 YTKCHNSNI---CIPRVYLCDGDNDCGDNSDENPTYCTTHTCSSSEFQCASGRCIPQHWY 2882
Query: 3546 CDGTLDCRDGSDEKGC----KKECA---IVCDNS-CVHADDLCDGKKKCNDGSDEDEE-A 3394
CD DC D SDE ++ C CD C+ ++ +CDG C D SDED+
Sbjct: 2883 CDQETDCFDASDEPASCGHSERTCLADEFKCDGGRCIPSEWICDGDNDCGDMSDEDKRHQ 2942
Query: 3393 CVIKQLLEKE---------NRKC--GGFACDGIVDCEDGSDE-KGCPDLECH-------- 3274
C + + E +R+C + CDG VDC DG DE + C C
Sbjct: 2943 CQNQNCSDSEFLCVNDRPPDRRCIPQSWVCDGDVDCTDGYDENQNCTRRTCSENEFTCGY 3002
Query: 3273 -LASNKSLICDGTIDCSSGKDENNC-HNNGESNFFQCSM-QTIKEWQVCDGRWDCADGLD 3103
L K CD DC DE C + + N F C + I + VCD DC DG D
Sbjct: 3003 GLCIPKIFRCDRHNDCGDYSDERGCLYQTCQQNQFTCQNGRCISKTFVCDEDNDCGDGSD 3062
Query: 3102 ESPEMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDE-----NPIHCKDMCK 2938
E +C + + C + D +C+++ LC+ + DC D SDE N H +
Sbjct: 3063 ELMHLCHTPEPTCPPHEFKCDNGRCIEMMK-LCNHLDDCLDNSDEKGCGINECHDPSISG 3121
Query: 2937 GKYRCTNGRCIDVSARXXXXXXXXXXXXXXXXGAECHHFG-VCAQKCWMAFNHTARCHCA 2761
+ CT+ EC VC+QKC C CA
Sbjct: 3122 CDHNCTD-TLTSFYCSCRPGYKLMSDKRTCVDIDECTEMPFVCSQKCENVIGSYI-CKCA 3179
Query: 2760 PGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDF 2581
PGY R + D C + + E ++ NR +L +L ++ +++ + + +
Sbjct: 3180 PGYLR-EPDGKTCRQ-NSNIEPYLIFSNRYYLRNL-----TIDGYFYSLILEGLDNVVAL 3232
Query: 2580 GYDVFRTTLMYTVGIGNSRVD--IRSKKWSDGLIGSWGEEESTAGLITYDFMHNNVYFTE 2407
+D L Y + ++ +K + +I A + D++ +Y+ +
Sbjct: 3233 DFDRVEKRL-YWIDTQRQVIERMFLNKTNKETII---NHRLPAAESLAVDWVSRKLYWLD 3288
Query: 2406 SSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINS--------LAVDPIKRLIFWT 2251
+ R ++V+ R L + N+ LA+ P ++W
Sbjct: 3289 A----------RLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLYWA 3338
Query: 2250 TSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKR 2071
I +DG ++ + P + +D++N+ LYW D
Sbjct: 3339 DWGHRAYIGRVGMDG-----------TNKSVIISTKLEWPNGITIDYTNDLLYWADAHLG 3387
Query: 2070 TIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGKTNKYVQK 1894
IE +G R TV L P + + IY ++ + +K+ G + +
Sbjct: 3388 YIEYSDLEGHHRHTVYDGAL-PHPFAITIFEDTIYWTDWNTRTVEKGNKYDGSNRQTL-- 3444
Query: 1893 IREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLCGPG 1714
+ I V HP + + NPC ++ + +C+ G C C P
Sbjct: 3445 VNTTHRPFDIHVYHPYRQPI-----VSNPCGTNNGGCSHLCLIKPGGKGF---TCEC-PD 3495
Query: 1713 RFFEVSTKKCMQLREKDQEASQCG--DYFCYNNAGCSP-------QKTC--------VCP 1585
F + +QL C + C NN C P QK C +CP
Sbjct: 3496 DF------RTLQLSGSTYCMPMCSSTQFLCANNEKCIPIWWKCDGQKDCSDGSDELALCP 3549
Query: 1584 PGFYGRQCEINECSETCWNGETCAVQEFGSTTNVVCHCP--SNYTQSSCATNVCEGVCGP 1411
F C + + C +G + Q + N +CP S+ + C + C+
Sbjct: 3550 QRF----CRLGQFQ--CSDGNCTSPQ---TLCNAHQNCPDGSDEDRLLCENHHCD---SN 3597
Query: 1410 RGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHKADAKVCYGHCFSGGACDGEGPLNL 1231
C C + C +++ CE + HC + + C +G ++
Sbjct: 3598 EWQCANKRCIPESWQCDTFNDCEDNSDEDSSHCASRT-CRPGQFRCANGRCIPQAWKCDV 3656
Query: 1230 RCSCGDGLTGNRCQNCV--GHECLNGGFCSYANSNRSLPHCI-------CPSGFTGDHCE 1078
CGD + + C+ H C N S + R +P C CE
Sbjct: 3657 DNDCGDH-SDEPIEECMSSAHLCDNFTEFSCKTNYRCIPKWAVCNGVDDCRDNSDEQGCE 3715
Query: 1077 EYLCKDACPFGSKCTYDITKPMDPITCSCE-QNAAAHNTD---CSP--------ICQKQ- 937
E C F K + I P+ C+ QN N+D C+P C Q
Sbjct: 3716 ERTCHPVGDFRCKNHHCI-----PLRWQCDGQNDCGDNSDEENCAPRECTESEFRCVNQQ 3770
Query: 936 ---PNW-CHNGGRCLDTPGYPGKCK---CLPRF----------AGPRCDVPVQCDDYCTN 808
W C + C D C+ C P + + +CD C D ++
Sbjct: 3771 CIPSRWICDHYNDCGDNSD-ERDCEMRTCHPEYFQCTSGHCVHSELKCDGSADCLD-ASD 3828
Query: 807 NSKC-------TITNGTHFECD---CKPGFKGLRCEQETKCSECSNEA--KCIKKPSGT- 667
+ C T FEC C P + +C+ + C + S+E C+ P +
Sbjct: 3829 EADCPTRFPDGAYCQATMFECKNHVCIPPY--WKCDGDDDCGDGSDEELHLCLDVPCNSP 3886
Query: 666 --------------VIC----QCPQGLG--GEYCEKITATSCHQLECKNG-GYCLKPD-- 556
+C C G E+C K T C + E K G G+C+ D
Sbjct: 3887 NRFRCDNNRCIYSHEVCNGVDDCGDGTDETEEHCRKPTPKPCTEYEYKCGNGHCIPHDNV 3946
Query: 555 ----PSANRTSPTCLCSPGFKGLLCSSNACENFC--LHDGN--CTLDEYFE 427
S C+ G K C+ N CE C L++G C+ FE
Sbjct: 3947 CDDADDCGDWSDELGCNKG-KERTCAENICEQNCTQLNEGGFICSCTAGFE 3996
Score = 319 bits (817), Expect = 7e-85
Identities = 220/724 (30%), Positives = 333/724 (45%), Gaps = 16/724 (2%)
Frame = -1
Query: 6261 TSQCIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPK 6082
+ CI W+CDGT DC D +DE C V G F C + C+P
Sbjct: 37 SGHCIPADWRCDGTKDCSDDADEIGCAVVTCQQG-------------YFKCQSEGQCIPS 83
Query: 6081 HWQCDGQPDCADGSDEK-NCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQC 5905
W CD DC DGSDE+ +C C+S + +C S+ +CIP E +CD RDCPDG DE+ C
Sbjct: 84 SWVCDQDQDCDDGSDERQDCSQSTCSSHQITC-SNGQCIPSEYRCDHVRDCPDGADENDC 142
Query: 5904 E-TECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSR 5728
+ C+ C N C + +CD DC D+ SDE++C H
Sbjct: 143 QYPTCEQ------LTCDNGACYNTSQKCDWKVDCRDS-----SDEINCT--EICLHNEFS 189
Query: 5727 CADETCVVACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDA 5548
C + C+ A +CD DC DG DE C C ++ C SG+CI +CD
Sbjct: 190 CGNGECIP----RAYVCDHDNDCQDGSDEHACNY--PTCGGYQFTCPSGRCIYQNWVCDG 243
Query: 5547 SVDCVDGSDEWVEICSLSEPPRRGC-PSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDE 5371
DC D DE + C C P WSC + C+ ++CDG DC DE
Sbjct: 244 EDDCKDNGDE--DGCESGPHDVHKCSPREWSCPESG---RCISIYKVCDGILDCPGREDE 298
Query: 5370 QCDNPQGNCSSTR-NSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCP-KANC 5197
+ CS T ++ + + C +C C GY ++ D +TC+ C C
Sbjct: 299 NNTSTGKYCSMTLCSALNCQYQCHETPYGGACFCPPGYIINHNDSRTCVEFDDCQIWGIC 358
Query: 5196 SHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTI-EAEILMVYGHRLKLFTIDGHAKAT 5020
C + R H C C GYIL Q C+ ND+ EA I+ G L + I G +
Sbjct: 359 DQKC-ESRPGRHLCHCEEGYILERGQY-CKANDSFGEASIIFSNGRDLLIGDIHGRSFRI 416
Query: 5019 LLSNLTNGVALD--YDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGI 4846
L+ + GVA+ + V+WTD NK + N N V+N + + + +
Sbjct: 417 LVESQNRGVAVGVAFHYHLQRVFWTDTVQ--NKVFSVDI-NGLNIQEVLN-VSVETPENL 472
Query: 4845 AVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDW-- 4672
AVDW+ IY + + I + ++ G + R+ L L PR I +DP +F++DW
Sbjct: 473 AVDWVNNKIYLVETKVNRIDMVNLDGSY-RVTLITENLGHPRGIAVDPTVGYLFFSDWES 531
Query: 4671 -GASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSK 4495
+ R MDGSN + +++ + + WP + +D ++R+Y+ D+ DYI + YDG +
Sbjct: 532 LSGEPKLERAFMDGSNRKDLVKTK-LGWPAGVTLDMISKRVYWVDSRFDYIETVTYDGIQ 590
Query: 4494 RRMVLRGS--VRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFK 4321
R+ V+ G + H F +++FE V+++DW + + +K T TN +V Q RP G
Sbjct: 591 RKTVVHGGSLIPHPFGVSLFEGQVFFTDWTKMAVLKANKFTETNPQVYYQ-ASLRPYGVT 649
Query: 4320 IVHPSLQSMGSLKTARHPC-SQPARCDNLCIPANTPDLTTSSDNFTCMCAQGFR--SEGR 4150
+ H Q A +PC C+ +C+ ++ D F C C GF+ ++ R
Sbjct: 650 VYHSLRQPY-----ATNPCKDNNGGCEQVCVLSHRTD--NDGLGFRCKCTFGFQLDTDER 702
Query: 4149 SCVS 4138
C++
Sbjct: 703 HCIA 706
Score = 288 bits (736), Expect = 2e-75
Identities = 237/840 (28%), Positives = 363/840 (43%), Gaps = 63/840 (7%)
Frame = -1
Query: 5250 PYDKKTCLRSPSCPKANCSHFCI-----DRRDVGHQCFCAPGYILSENQKDCR--RNDTI 5092
PY C + C C+ D +G +C C G+ L +++ C +N I
Sbjct: 657 PYATNPCKDN----NGGCEQVCVLSHRTDNDGLGFRCKCTFGFQLDTDERHCIAVQNFLI 712
Query: 5091 EAEILMVYGHRLKLFTIDGHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITS 4912
+ + + G L T + + N + V +D+D + ++++D++ K I
Sbjct: 713 FSSQVAIRGIPFTLSTQED-VMVPVSGNPSFFVGIDFDAQDSTIFFSDMS----KHMIFK 767
Query: 4911 MSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPL 4732
++ + + ++ +A DW+ +N+Y+TD ++ +I+V + + R +++ L
Sbjct: 768 QKIDGTGREILAANRVENVESLAFDWISKNLYWTDSHYKSISVMRLADKTRRTVVQY--L 825
Query: 4731 NDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRL 4552
N+PR++V+ P +F+TDW A I R DGS+ ++ + T+ WPN LA+D A RL
Sbjct: 826 NNPRSVVVHPFAGYLFFTDWFRPAKIMRAWSDGSHLLPVI-NTTLGWPNGLAIDWAASRL 884
Query: 4551 YFGDAHRDYIASCNYDG-SKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITG 4375
Y+ DA+ D I +DG +RR+ + H F LA+F ++++++DW I RV K G
Sbjct: 885 YWVDAYFDKIEHSTFDGLDRRRLGHIEQMTHPFGLAIFGEHLFFTDWRLGAIIRVRKADG 944
Query: 4374 TNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPAR----CDNLCIPANTPDLT 4207
V+ Y I+H + +++T + C+QP C + C P
Sbjct: 945 GEMTVIRSGIAY------ILHLKSYDV-NIQTGSNACNQPTHPNGDCSHFCFPV------ 991
Query: 4206 TSSDNF--TCMCAQGFRSEGRSCVSECKPND-----------FVCTKTYKCISSWWRXXX 4066
NF C C G R E P + F C K +C+ +++
Sbjct: 992 ---PNFQRVCGCPYGMRLASNHLTCEGDPTNEPPTEQCGLFSFPC-KNGRCVPNYYLCDG 1047
Query: 4065 XXXXXXXXXXGYFVEGVCPPF--PCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGD 3892
E +C C + F CG +C+ A CD DC G
Sbjct: 1048 VDDCHDNSD-----EQLCGTLNNTCSSSAFTCGH------GECIPAHWRCDKRNDCVDGS 1096
Query: 3891 DEE--PAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEIT-SCKPDFF 3721
DE P C + Q+ C D +CI VCD + DC DGSDE NC T +C+P F
Sbjct: 1097 DEHNCPTHAP-ASCLDTQYTC-DNHQCISKNWVCDTDNDCGDGSDEKNCNSTETCQPSQF 1154
Query: 3720 ACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSG-KCIPKRRQC 3544
C N +CI F CDG+ DC +G DE + CT QF+C SG KCI +C
Sbjct: 1155 NCPN----HRCIDLSFVCDGDKDCVDGSDEVGC---VLNCTASQFKCASGDKCIGVTNRC 1207
Query: 3543 DGTLDCRDGSDEKGCKKECAIVC---------DNSCVHADDLCDGKKKCNDGSDEDEEAC 3391
DG DC D SDE GC +C D C+ CDG C GSDE AC
Sbjct: 1208 DGVFDCSDNSDEAGCPTRPPGMCHSDEFQCQEDGICIPNFWECDGHPDCLYGSDE-HNAC 1266
Query: 3390 VIK----QLLEKENRKC--GGFACDGIVDCEDGSDEKGCPD------------LECHLAS 3265
V K +N C + CD DC D SDEK CP L ++
Sbjct: 1267 VPKTCPSSYFHCDNGNCIHRAWLCDRDNDCGDMSDEKDCPTQPFRCPSWQWQCLGHNICV 1326
Query: 3264 NKSLICDGTIDCSSGKDENN-CHNNGESNF-FQCSMQTIKEWQVCDGRWDCADGLDESPE 3091
N S++CDG DC +G DE+ C+ N S+F C+ + ++E
Sbjct: 1327 NLSVVCDGIFDCPNGTDESPLCNGNSCSDFNGGCTHECVQE------------------- 1367
Query: 3090 MCASRKARCF-RIGY--CDDKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKGKYRCT 2920
A+C +G+ +D K C D+ CD + C HC +M +G +RC+
Sbjct: 1368 ---PFGAKCLCPLGFLLANDSKTCEDIDE--CDILGSCSQ-------HCYNM-RGSFRCS 1414
Score = 228 bits (581), Expect = 2e-57
Identities = 215/806 (26%), Positives = 322/806 (39%), Gaps = 30/806 (3%)
Frame = -1
Query: 3999 CIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKK 3820
C + F CG + C+ A CDG KDCS DD + C C + FKC + +
Sbjct: 28 CDSAHFRCG------SGHCIPADWRCDGTKDCS--DDADEIGCAVVTCQQGYFKCQSEGQ 79
Query: 3819 CIPLTSVCDKEKDCDDGSDE-LNCEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPE 3643
CIP + VCD+++DCDDGSDE +C ++C C NG +CIP E+ CD DCP+
Sbjct: 80 CIPSSWVCDQDQDCDDGSDERQDCSQSTCSSHQITCSNG----QCIPSEYRCDHVRDCPD 135
Query: 3642 GQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQCDGTLDCRDGSDEKGCKKEC---AIVCD 3472
G DE D + T EQ C +G C ++CD +DCRD SDE C + C C
Sbjct: 136 GADENDCQYP----TCEQLTCDNGACYNTSQKCDWKVDCRDSSDEINCTEICLHNEFSCG 191
Query: 3471 N-SCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKENRKCGGFACDGIVDCEDGSDEKG 3295
N C+ +CD C DGS DE AC CGG+ +
Sbjct: 192 NGECIPRAYVCDHDNDCQDGS--DEHAC--------NYPTCGGY-------------QFT 228
Query: 3294 CPDLECHLASNKSLICDGTIDCSSGKDENNCHNNGESNFFQCSM---------QTIKEWQ 3142
CP C ++ +CDG DC DE+ C +G + +CS + I ++
Sbjct: 229 CPSGRC---IYQNWVCDGEDDCKDNGDEDGC-ESGPHDVHKCSPREWSCPESGRCISIYK 284
Query: 3141 VCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDENP 2962
VCDG DC DE+ YC S LC + +C E P
Sbjct: 285 VCDGILDCPGREDENNTSTGK---------YC---------SMTLCSAL-NCQYQCHETP 325
Query: 2961 IHCKDMCKGKYRCTNG---RCIDVSARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMA 2791
C Y + C++ +C +G+C QKC
Sbjct: 326 YGGACFCPPGYIINHNDSRTCVEFD--------------------DCQIWGICDQKCESR 365
Query: 2790 FNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQVSVLRPVFNIK 2611
CHC GY + + A + +NG L + + +L N
Sbjct: 366 PGRHL-CHCEEGYILERGQYCKANDSFGEASIIFSNGRDLLIGDIHGRSFRILVESQN-- 422
Query: 2610 MNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGLITYDFM 2431
+ G+ F Y + R TV VDI + L S E+ A D++
Sbjct: 423 -RGVAVGVAFHYHLQRVFWTDTVQNKVFSVDINGLNIQEVLNVSVETPENLA----VDWV 477
Query: 2430 HNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIF-- 2257
+N +Y E ++ NR + + + V TLI + G +AVDP +F
Sbjct: 478 NNKIYLVE-TKVNRIDMVNLDGSYRV---------TLITENLGHPRGIAVDPTVGYLFFS 527
Query: 2256 -WTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDV 2080
W + + P++ A +DG K LV+ + P + LD ++R+YW+D
Sbjct: 528 DWESLSGEPKLERAFMDG-----------SNRKDLVKTKLGWPAGVTLDMISKRVYWVDS 576
Query: 2079 LKRTIETVSFDGRDRRT-VRKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGKTNK 1906
IETV++DG R+T V L P + + G ++ + ++ + +KFT
Sbjct: 577 RFDYIETVTYDGIQRKTVVHGGSLIPHPFGVSLFEGQVFFTDWTKMAVLKANKFT----- 631
Query: 1905 YVQKIREVSPRIQIRVA-HPAKHTVSHITHQ---KNPCQSDYCPSNTVCV----PDQDKN 1750
E +P++ + + P TV H Q NPC+ + VCV D D
Sbjct: 632 ------ETNPQVYYQASLRPYGVTVYHSLRQPYATNPCKDNNGGCEQVCVLSHRTDNDGL 685
Query: 1749 GILIPKCLCGPGRFFEVSTKKCMQLR 1672
G +C C G + + C+ ++
Sbjct: 686 GF---RCKCTFGFQLDTDERHCIAVQ 708
Score = 211 bits (538), Expect = 1e-52
Identities = 221/833 (26%), Positives = 323/833 (38%), Gaps = 57/833 (6%)
Frame = -1
Query: 4005 FPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDK 3826
FP Q VCG C Y +L C G EP +C F C +
Sbjct: 989 FPVPNFQRVCG---------CPYGMRLASNHLTCEGDPTNEPP---TEQCGLFSFPCKNG 1036
Query: 3825 KKCIPLTSVCDKEKDCDDGSDELNCEI--TSCKPDFFACFNGTAISKCIPKEFYCDGEDD 3652
+ C+P +CD DC D SDE C +C F C +G +CIP + CD +D
Sbjct: 1037 R-CVPNYYLCDGVDDCHDNSDEQLCGTLNNTCSSSAFTCGHG----ECIPAHWRCDKRND 1091
Query: 3651 CPEGQDEPDS-CFGIGECTHEQFQCTSGKCIPKRRQCDGTLDCRDGSDEKGCK-----KE 3490
C +G DE + C Q+ C + +CI K CD DC DGSDEK C +
Sbjct: 1092 CVDGSDEHNCPTHAPASCLDTQYTCDNHQCISKNWVCDTDNDCGDGSDEKNCNSTETCQP 1151
Query: 3489 CAIVCDNS-CVHADDLCDGKKKCNDGSDEDEEA--CVIKQLLEKENRKCGGFA--CDGIV 3325
C N C+ +CDG K C DGSDE C Q KC G CDG+
Sbjct: 1152 SQFNCPNHRCIDLSFVCDGDKDCVDGSDEVGCVLNCTASQFKCASGDKCIGVTNRCDGVF 1211
Query: 3324 DCEDGSDEKGCPDLE---CH----------LASNKSLICDGTIDCSSGKDENNC--HNNG 3190
DC D SDE GCP CH + CDG DC G DE+N
Sbjct: 1212 DCSDNSDEAGCPTRPPGMCHSDEFQCQEDGICIPNFWECDGHPDCLYGSDEHNACVPKTC 1271
Query: 3189 ESNFFQCSM-QTIKEWQVCDGRWDCADGLDESPEMCASRKARCFRIGY-CDDKKQCLDVS 3016
S++F C I +CD DC D DE C ++ RC + C C+++S
Sbjct: 1272 PSSYFHCDNGNCIHRAWLCDRDNDCGDMSDEKD--CPTQPFRCPSWQWQCLGHNICVNLS 1329
Query: 3015 TALCDGIRDCFDGSDENPI----HCKDMCKGKYRCTNGRCID----VSARXXXXXXXXXX 2860
+CDGI DC +G+DE+P+ C D G CT+ C+
Sbjct: 1330 V-VCDGIFDCPNGTDESPLCNGNSCSDFNGG---CTH-ECVQEPFGAKCLCPLGFLLAND 1384
Query: 2859 XXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECE-PLSKSAEMFITN 2683
EC G C+Q C+ + RC C GY ++D C+ S+S + + +
Sbjct: 1385 SKTCEDIDECDILGSCSQHCYN-MRGSFRCSCDTGYM-LESDGRTCKVTASESLLLLVAS 1442
Query: 2682 GNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKK 2503
N++ SV V NI +L+ G Y V + + R
Sbjct: 1443 QNKI-------IADSVTSQVHNI-YSLVENG------------SYIVAVDFDSISGRIF- 1481
Query: 2502 WSDGLIG-SWGEEESTAG-------------LITYDFMHNNVYFTESSEQNRGVLFDRQA 2365
WSD G +W ++ I D++ N+Y+T+ + +
Sbjct: 1482 WSDATQGKTWSAFQNGTDRRVVFDSSIILTETIAIDWVGRNLYWTDYALET--------- 1532
Query: 2364 NIYVAKAKDTSTRTLIVNSTGTINSLAVDPI--KRLIFWTTSAPVPRILSANLDGKPIAQ 2191
I V+K + LI + LA+DP + L+FW+ PRI A++DG
Sbjct: 1533 -IEVSKIDGSHRTVLISKNLTNPRGLALDPRMNEHLLFWSDWGHHPRIERASMDG----- 1586
Query: 2190 PFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFEL 2011
+V+ IF P + +D+ N LY++D ++ ++G RR V +L
Sbjct: 1587 ------SMRTVIVQDKIFWPCGLTIDYPNRLLYFMDSYLDYMDFCDYNGHHRRQVIASDL 1640
Query: 2010 -GDTPVTMDVLGGYIYLITR-QGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHT 1837
P + + +Y R + R +K+ G V + + + I HP+K
Sbjct: 1641 IIRHPYALTLFEDSVYWTDRATRRVMRANKWHGGNQSVV--MYNIQWPLGIVAVHPSKQ- 1697
Query: 1836 VSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQ 1678
+ NPC C + +C+ G C+C G C++
Sbjct: 1698 ----PNSVNPCAFSRC--SHLCL--LSSQGPHFYSCVCPSGWSLSPDLLNCLR 1742
Score = 153 bits (387), Expect = 5e-35
Identities = 105/320 (32%), Positives = 144/320 (44%), Gaps = 34/320 (10%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC---TCNENEFRCQ 6403
D+ D + C+ R C F C N CIP + +C+ NDC + +DE +C TC+ F+C
Sbjct: 3747 DNSDEENCAPRECTESEFRCVNQQCIPSRWICDHYNDCGDNSDERDCEMRTCHPEYFQCT 3806
Query: 6402 SGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDG 6223
SG C+ S+ +C+ DC DASDE CP R + + C CI P WKCDG
Sbjct: 3807 SGHCVHSELKCDGSADCLDASDEADCPTRFPD--GAYCQATMFEC-KNHVCIPPYWKCDG 3863
Query: 6222 TNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADG 6043
+DC DGSDE + + D C++ +F C R C+ H C+G DC DG
Sbjct: 3864 DDDCGDGSDE-ELHLCLDV---------PCNSPNRFRCDNNR-CIYSHEVCNGVDDCGDG 3912
Query: 6042 SD--EKNC---DAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGED------------- 5917
+D E++C K CT +E+ C + CIP + CD DC D D
Sbjct: 3913 TDETEEHCRKPTPKPCTEYEYKC-GNGHCIPHDNVCDDADDCGDWSDELGCNKGKERTCA 3971
Query: 5916 EHQCETECDS-KGGNATFRCT---------NHRCIPMAWRCDGTDDCMDNAKSL-GSDEV 5770
E+ CE C G CT C+ + C+ C + ++ GS E
Sbjct: 3972 ENICEQNCTQLNEGGFICSCTAGFETNVFDRTSCLDIN-ECEQFGTCPQHCRNTKGSYEC 4030
Query: 5769 DCAAGRTSF--HVPSRCADE 5716
CA G TS RCA E
Sbjct: 4031 VCADGFTSMSDRPGKRCAAE 4050
Score = 125 bits (314), Expect = 1e-26
Identities = 100/377 (26%), Positives = 171/377 (44%), Gaps = 20/377 (5%)
Frame = -1
Query: 5214 CPKANCSHFCIDRRDVGH--QCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTI 5041
C + CSH C+ H C C G+ LS + +C R+D + ++ V H + ++
Sbjct: 1704 CAFSRCSHLCLLSSQGPHFYSCVCPSGWSLSPDLLNCLRDD--QPFLITVRQHIIFGISL 1761
Query: 5040 DGHAKAT----LLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINS 4873
+ K+ ++ + NG+ +++D +YW + N I + V S
Sbjct: 1762 NPEVKSNDAMVPIAGIQNGLDVEFDDAEQYIYWVE-----NPGEIHRVKTDGTNRTVFAS 1816
Query: 4872 LPTKGID-GIAVDWLGRNIYYTDRNHDAIAVCDMRG--RFNRILLK--GTPLND--PRAI 4714
+ G +A+DW+ RN+Y T+ +I V + G R+ + L+ GT L P I
Sbjct: 1817 ISMVGPSMNLALDWISRNLYSTNPRTQSIEVLTLHGDIRYRKTLIANDGTALGVGFPIGI 1876
Query: 4713 VLDPLQALVFW----TDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYF 4546
+DP + ++W TD G A I NMDG++ + + + + +D Q+LY+
Sbjct: 1877 TVDPARGKLYWSDQGTDSGVPAKIASANMDGTSVKTLFTGN-LEHLECVTLDIEEQKLYW 1935
Query: 4545 GDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNR 4366
R I N DG+ R M+L + H + +AV + ++Y++D IERV K TG N
Sbjct: 1936 AVTGRGVIERGNVDGTDR-MILVHQLSHPWGIAVHDSFLYYTDEQYEVIERVDKATGAN- 1993
Query: 4365 KVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPAR-CDNLCIPANTPDLTTSSDNF 4189
K++++D G ++ H + S + CS C +C+P F
Sbjct: 1994 KIVLRDNVPNLRGLQVYHRRNAAESS-----NGCSNNMNACQQICLP-------VPGGLF 2041
Query: 4188 TCMCAQGFR--SEGRSC 4144
+C CA GF+ + RSC
Sbjct: 2042 SCACATGFKLNPDNRSC 2058
Score = 108 bits (269), Expect = 2e-21
Identities = 98/368 (26%), Positives = 160/368 (42%), Gaps = 16/368 (4%)
Frame = -1
Query: 5199 CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDT--IEAEILMVYGHRLKLFTIDGHAK 5026
C C+ C CA G+ L+ + + C ++ + + + + G L+L +
Sbjct: 2029 CQQICLPVPGGLFSCACATGFKLNPDNRSCSPYNSFIVVSMLSAIRGFSLEL-SDHSETM 2087
Query: 5025 ATLLSNLTNGVALDYDVKSDLVYWTD----VAHDGN----KAGITSMSNQPNTYRVINSL 4870
+ N + +D DV S +YW D VA D K +S+ N V + +
Sbjct: 2088 VPVAGQGRNALHVDVDVSSGFIYWCDFSSSVASDNAIRRIKPDGSSLMNI-----VTHGI 2142
Query: 4869 PTKGIDGIAVDWLGRNIYYTDR--NHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQ 4696
G+ GIAVDW+ N+Y+T+ + I V + + R+LLK T ++ PR IV+DP
Sbjct: 2143 GENGVRGIAVDWVAGNLYFTNAFVSETLIEVLRINTTYRRVLLKVT-VDMPRHIVVDPKN 2201
Query: 4695 ALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIAS 4516
+FW D+G I R +D +N V++ + + P LAVD +Y+ D D IA
Sbjct: 2202 RYLFWADYGQRPKIERSFLDCTNRTVLVSEGIVT-PRGLAVDRSDGYVYWVDDSLDIIAR 2260
Query: 4515 CNYDGSKRRMVLRGS-VRHIFALAVFEDYVYWSDWHNHTIERVHK-ITGTNRKVLIQDKQ 4342
+G ++ GS + + VFE+ + W D + I + K T +I+D
Sbjct: 2261 IRINGENSEVIRYGSRYPTPYGITVFENSIIWVDRNLKKIFQASKEPENTEPPTVIRDNI 2320
Query: 4341 YRPMGFKIVHPSLQSMGSLKTARHPC-SQPARCDNLCIPANTPDLTTSSDNFTCMCAQG- 4168
I +Q + +PC C +LC P L T C CA G
Sbjct: 2321 NWLRDVTIFDKQVQPRSPAEVNNNPCLENNGGCSHLCFA--LPGLHTPK----CDCAFGT 2374
Query: 4167 FRSEGRSC 4144
+S+G++C
Sbjct: 2375 LQSDGKNC 2382
Score = 103 bits (256), Expect = 7e-20
Identities = 105/385 (27%), Positives = 143/385 (36%), Gaps = 58/385 (15%)
Frame = -1
Query: 6012 CTSFEFSCESSKKCIP----LEQKCDGRRDCPDGEDEHQCETECDSKGGNATFRCTNHRC 5845
C F C S C P E +C + + C + + G ++F C+N RC
Sbjct: 2655 CEQFNGGC--SHICAPGPNGAECQCPHEGNWYLANNRKHCIVDNGERCGASSFTCSNGRC 2712
Query: 5844 IPMAWRCDGTDDCMDNAKSLGSDEVD-CAAGRTSFHVPSRCADETCVVACELTAVLCDGI 5668
I W+CD +DC D GSDE++ A T CA+ CV + CD
Sbjct: 2713 ISEEWKCDNDNDCGD-----GSDEMESVCALHTCSPTAFTCANGRCV----QYSYRCDYY 2763
Query: 5667 QDCSDGFDEKNCASLDRQCK-PNEWMCDSGQCIDSGRLCDASVDCVDGSDEWVEICSLSE 5491
DC DG DE C L R C E+MC++ +CI +C+ +C D + + C
Sbjct: 2764 NDCGDGSDEAGC--LFRDCNATTEFMCNNRRCIPREFICNGVDNCHDNNTSDEKNC---- 2817
Query: 5490 PPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQ--------CDNPQGNCSST 5335
P R C SG++ N I C+ LCDG DC DE C + + C+S
Sbjct: 2818 -PDRTCQSGYT-KCHNSNI-CIPRVYLCDGDNDCGDNSDENPTYCTTHTCSSSEFQCASG 2874
Query: 5334 RNSCDQTWNCQRH-----AGFESCSCDDGYHLSPYDKKTC-------------------- 5230
R Q W C + A E SC D+ C
Sbjct: 2875 R-CIPQHWYCDQETDCFDASDEPASCGHSERTCLADEFKCDGGRCIPSEWICDGDNDCGD 2933
Query: 5229 ----LRSPSCPKANCS---HFCIDRRDVGHQCF-----------CAPGYILSENQKDCRR 5104
+ C NCS C++ R +C C GY ENQ +C R
Sbjct: 2934 MSDEDKRHQCQNQNCSDSEFLCVNDRPPDRRCIPQSWVCDGDVDCTDGY--DENQ-NCTR 2990
Query: 5103 NDTIEAEILMVYGHRL-KLFTIDGH 5032
E E YG + K+F D H
Sbjct: 2991 RTCSENEFTCGYGLCIPKIFRCDRH 3015
Score = 98.2 bits (243), Expect = 2e-18
Identities = 191/868 (22%), Positives = 314/868 (36%), Gaps = 65/868 (7%)
Frame = -1
Query: 2820 GVCAQKCW-MAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQ 2644
G C+ C+ + HT +C CA + ++D C +++ +F + N L + L+
Sbjct: 2351 GGCSHLCFALPGLHTPKCDCA--FGTLQSDGKNCAISTENFLIFALS-NSLRSLHLDPEN 2407
Query: 2643 VSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGN-SRVDIRSKKWSDGLIGSWGEE 2467
S N++ ++ D D T G+G S + S + +I S
Sbjct: 2408 HSPPFQTINVERTVMSLDYDSVSDRIYFTQNLASGVGQISYATLSSGIHTPTVIASG--- 2464
Query: 2466 ESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSL 2287
TA I +D++ +Y+++ Q + + A+D S RT+I ++
Sbjct: 2465 IGTADGIAFDWITRRIYYSDYLNQ-----------MINSMAEDGSNRTVIARVPKP-RAI 2512
Query: 2286 AVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFS 2107
+DP + ++W +I A L G F+ +V ++ P+ + LD+
Sbjct: 2513 VLDPCQGYLYWADWDTHAKIERATLGGN-----FRV------PIVNSSLVMPSGLTLDYE 2561
Query: 2106 NERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIY---LITRQGSIHR 1936
+ LYW+D + IE + G DR + + +T+ G YIY L T++ I+R
Sbjct: 2562 EDLLYWVDASLQRIERSTLTGVDREVIVNAAVHAFGLTL--YGQYIYWTDLYTQR--IYR 2617
Query: 1935 MHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYC---PSNTVCVP 1765
+K+ G + PR V K ++ Q N S C P+ C
Sbjct: 2618 ANKYDGSGQIAMTTNLLSQPRGINTVVKNQKQQCNNPCEQFNGGCSHICAPGPNGAECQC 2677
Query: 1764 DQDKNGILI---PKCLCGPGR-----FFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCS 1609
+ N L C+ G F S +C+ K + CGD + C+
Sbjct: 2678 PHEGNWYLANNRKHCIVDNGERCGASSFTCSNGRCISEEWKCDNDNDCGDGSDEMESVCA 2737
Query: 1608 PQKTC-----VCPPG---FYGRQCE-INECSETCWNGETCAVQEFGSTTNVVCHCPSNYT 1456
TC C G Y +C+ N+C + + C ++ +TT +C N
Sbjct: 2738 -LHTCSPTAFTCANGRCVQYSYRCDYYNDCGDGS-DEAGCLFRDCNATTEFMC----NNR 2791
Query: 1455 QSSCATNVCEGV--CGPRGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHKADAKVCY 1282
+ +C GV C + DE +C + C G+T H ++ +C
Sbjct: 2792 RCIPREFICNGVDNCHDNNT-------SDEKNCPDRT---CQSGYTKCH-----NSNICI 2836
Query: 1281 GHCFSGGACDGEGPLNLRCSCGDGLTGNRCQNCVGHECLNGGFCSYANSNRSLP-HCICP 1105
+ CDG+ CGD N C H C + F S R +P H C
Sbjct: 2837 PRVY---LCDGDN------DCGDNSDENPTY-CTTHTCSSSEF--QCASGRCIPQHWYCD 2884
Query: 1104 SGFTGDHCEEYLCKDACPFGSKCTY-DITKPMDPITCSCEQNAAAH-----NTDCSPICQ 943
+E C DA + C + + T D C + + + DC +
Sbjct: 2885 --------QETDCFDASDEPASCGHSERTCLADEFKCDGGRCIPSEWICDGDNDCGDMSD 2936
Query: 942 KQPNWCHNGGRCLDTP-----GYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSKCTITNGT 778
+ C D+ P +C+P+ CD V C D N CT +
Sbjct: 2937 EDKRHQCQNQNCSDSEFLCVNDRPPDRRCIPQ--SWVCDGDVDCTDGYDENQNCTRRTCS 2994
Query: 777 HFECDCKPGF---KGLRCEQETKCSECSNEAKCIKKP--------------SGTVICQCP 649
E C G K RC++ C + S+E C+ + S T +C
Sbjct: 2995 ENEFTCGYGLCIPKIFRCDRHNDCGDYSDERGCLYQTCQQNQFTCQNGRCISKTFVCDED 3054
Query: 648 QGLGGEYCEKI-----TATSC--HQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCS 490
G E + +C H+ +C N G C++ N CL + KG C
Sbjct: 3055 NDCGDGSDELMHLCHTPEPTCPPHEFKCDN-GRCIEMMKLCNHLD-DCLDNSDEKG--CG 3110
Query: 489 SNACENFCLH--DGNCTLDEYFEPQCEC 412
N C + + D NCT D C C
Sbjct: 3111 INECHDPSISGCDHNCT-DTLTSFYCSC 3137
Score = 93.2 bits (230), Expect = 8e-17
Identities = 157/724 (21%), Positives = 252/724 (34%), Gaps = 40/724 (5%)
Frame = -1
Query: 2448 ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIK 2269
+ +D++ N+Y+T+S ++ I V + D + RT +V S+ V P
Sbjct: 789 LAFDWISKNLYWTDSHYKS----------ISVMRLADKTRRT-VVQYLNNPRSVVVHPFA 837
Query: 2268 RLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYW 2089
+F+T +I+ A DG + T + P + +D++ RLYW
Sbjct: 838 GYLFFTDWFRPAKIMRAWSDGSHLLPVINT-----------TLGWPNGLAIDWAASRLYW 886
Query: 2088 IDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTG-- 1918
+D IE +FDG DRR + E P + + G +++ R G+I R+ K G
Sbjct: 887 VDAYFDKIEHSTFDGLDRRRLGHIEQMTHPFGLAIFGEHLFFTDWRLGAIIRVRKADGGE 946
Query: 1917 -----KTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDK 1753
Y+ ++ IQ + + TH C S +C VP+ +
Sbjct: 947 MTVIRSGIAYILHLKSYDVNIQ-----TGSNACNQPTHPNGDC-SHFC----FPVPNFQR 996
Query: 1752 NGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCSPQKTCVCPPGFY 1573
C C G + C + QCG + P K C P +Y
Sbjct: 997 ------VCGCPYGMRLASNHLTCEGDPTNEPPTEQCGLF-------SFPCKNGRCVPNYY 1043
Query: 1572 GRQCE-INECSETCWNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVC---EGVCGPRG 1405
C+ +++C + + ++ T N C + + +C C C R
Sbjct: 1044 --LCDGVDDCHDN-------SDEQLCGTLNNTC----SSSAFTCGHGECIPAHWRCDKRN 1090
Query: 1404 SCKTVPCPKDEPHCRSYSFCEC-DKGWTGPHCRHKADAKVCYGH-CFS-GGACDGEGPLN 1234
C DE +C +++ C D +T C H C S CD +
Sbjct: 1091 DCVD---GSDEHNCPTHAPASCLDTQYT------------CDNHQCISKNWVCDTDN--- 1132
Query: 1233 LRCSCGDGLTGNRCQ----------NCVGHECLNGGFCSYANSNRSLPHCICPSGFTGDH 1084
CGDG C NC H C++ F + + C+ S G
Sbjct: 1133 ---DCGDGSDEKNCNSTETCQPSQFNCPNHRCIDLSFVCDGDKD-----CVDGSDEVGCV 1184
Query: 1083 CEEYLCKDACPFGSKCTYDITKPMDPI-TCSCEQNAAAHNTDCSPICQKQPNWCHNGGRC 907
+ C G KC +T D + CS + A T +C C G C
Sbjct: 1185 LNCTASQFKCASGDKC-IGVTNRCDGVFDCSDNSDEAGCPTRPPGMCHSDEFQCQEDGIC 1243
Query: 906 L----DTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSKCTITNGTHFECD---CKPGF 748
+ + G+P CL VP C ++F CD C
Sbjct: 1244 IPNFWECDGHP---DCLYGSDEHNACVPKTCP-------------SSYFHCDNGNCI--H 1285
Query: 747 KGLRCEQETKCSECSNEAKCIKKPSGTVICQCP----QGLGGEYCEKITATSCHQLECKN 580
+ C+++ C + S+E C +P +CP Q LG C ++ +C N
Sbjct: 1286 RAWLCDRDNDCGDMSDEKDCPTQP-----FRCPSWQWQCLGHNICVNLSVVCDGIFDCPN 1340
Query: 579 GGYCLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCLHDGNCT---LDEYFEPQCECY 409
G SP LC+ N+C +F +G CT + E F +C C
Sbjct: 1341 G----------TDESP-----------LCNGNSCSDF---NGGCTHECVQEPFGAKCLCP 1376
Query: 408 QAFI 397
F+
Sbjct: 1377 LGFL 1380
Score = 79.7 bits (195), Expect = 9e-13
Identities = 37/95 (38%), Positives = 48/95 (49%), Gaps = 7/95 (7%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADE-------SNCTCNENE 6415
D D + C + C+ F C NG CI + VC+ NDC + +DE TC +E
Sbjct: 3020 DYSDERGCLYQTCQQNQFTCQNGRCISKTFVCDEDNDCGDGSDELMHLCHTPEPTCPPHE 3079
Query: 6414 FRCQSGACIPSKARCNHMQDCNDASDEIGCPFRNC 6310
F+C +G CI CNH+ DC D SDE GC C
Sbjct: 3080 FKCDNGRCIEMMKLCNHLDDCLDNSDEKGCGINEC 3114
Score = 60.1 bits (144), Expect = 7e-07
Identities = 38/142 (26%), Positives = 62/142 (42%), Gaps = 10/142 (7%)
Frame = -1
Query: 6579 MFDDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCTCNENEFRCQS 6400
++ ++ C + C YF+C NG CI +C+R NDC + +DE +C FRC S
Sbjct: 1257 LYGSDEHNACVPKTCPSSYFHCDNGNCIHRAWLCDRDNDCGDMSDEKDCP--TQPFRCPS 1314
Query: 6399 --------GACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIH 6244
C+ C+ + DC + +DE P N ++ ++F N T +C+
Sbjct: 1315 WQWQCLGHNICVNLSVVCDGIFDCPNGTDE--SPLCNGNSCSDF------NGGCTHECVQ 1366
Query: 6243 PSW--KCDGTNDCYDGSDEKDC 6184
+ KC +D K C
Sbjct: 1367 EPFGAKCLCPLGFLLANDSKTC 1388
Score = 54.7 bits (130), Expect = 3e-05
Identities = 62/293 (21%), Positives = 107/293 (36%), Gaps = 1/293 (0%)
Frame = -1
Query: 2829 HHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLEN 2650
++ C Q C C CA G+ + D C P + + + + R + L +
Sbjct: 2024 NNMNACQQICLPVPGGLFSCACATGF-KLNPDNRSCSPYNSFIVVSMLSAIRGFSLELSD 2082
Query: 2649 SQVSVLRPVFNIKMNLIPGGIDFGYD-VFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWG 2473
+++ PV N + +D ++ +V N+ I+ S I + G
Sbjct: 2083 HSETMV-PVAGQGRNALHVDVDVSSGFIYWCDFSSSVASDNAIRRIKPDGSSLMNIVTHG 2141
Query: 2472 EEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTIN 2293
E+ I D++ N+YFT + F + I V + T R L+ +
Sbjct: 2142 IGENGVRGIAVDWVAGNLYFTNA--------FVSETLIEVLRINTTYRRVLLKVTVDMPR 2193
Query: 2292 SLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLD 2113
+ VDP R +FW P+I + LD LV I P + +D
Sbjct: 2194 HIVVDPKNRYLFWADYGQRPKIERSFLD-----------CTNRTVLVSEGIVTPRGLAVD 2242
Query: 2112 FSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITR 1954
S+ +YW+D I + +G + +R TP + V I + R
Sbjct: 2243 RSDGYVYWVDDSLDIIARIRINGENSEVIRYGSRYPTPYGITVFENSIIWVDR 2295
Score = 46.2 bits (108), Expect = 0.011
Identities = 86/356 (24%), Positives = 115/356 (32%), Gaps = 40/356 (11%)
Frame = -1
Query: 1650 QCGDYFCYNNAGCSPQKTCV-----CPPGFYGRQ-CEINECSE---TCWNGETCAVQEFG 1498
Q G + C + C P C G RQ C + CS TC NG+ C E+
Sbjct: 68 QQGYFKCQSEGQCIPSSWVCDQDQDCDDGSDERQDCSQSTCSSHQITCSNGQ-CIPSEY- 125
Query: 1497 STTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSYSFCECDKGWTGP 1318
+ V CP ++ C CE + G+C + +CD W
Sbjct: 126 -RCDHVRDCPDGADENDCQYPTCEQLTCDNGACYN-------------TSQKCD--WK-V 168
Query: 1317 HCRHKADAKVCYGHCFSGGACDGEGPLNLRC-------SCGDGLTGNRCQ--NCVGHE-C 1168
CR +D C C G G R C DG + C C G++
Sbjct: 169 DCRDSSDEINCTEICLHNEFSCGNGECIPRAYVCDHDNDCQDGSDEHACNYPTCGGYQFT 228
Query: 1167 LNGGFCSYANSNRSLPHCICPSGFTGDHCEE-----YLCKD---ACPFGSKCTYDITKPM 1012
G C Y N C D CE + C +CP +C I K
Sbjct: 229 CPSGRCIYQNWVCD-GEDDCKDNGDEDGCESGPHDVHKCSPREWSCPESGRC-ISIYKVC 286
Query: 1011 DPITCSCEQNAAAHNTD---------CSPI-CQKQPNWCHNGGRCLDTPGYPGKCKCLPR 862
D I C +NT CS + CQ Q + GG C PGY +
Sbjct: 287 DGI-LDCPGREDENNTSTGKYCSMTLCSALNCQYQCHETPYGGACFCPPGY-----IINH 340
Query: 861 FAGPRCDVPVQCDDYCTNNSKCTITNGTHFECDCKPGF---KGLRCEQETKCSECS 703
C C + + KC G H C C+ G+ +G C+ E S
Sbjct: 341 NDSRTCVEFDDCQIWGICDQKCESRPGRHL-CHCEEGYILERGQYCKANDSFGEAS 395
Score = 40.4 bits (93), Expect = 0.59
Identities = 17/40 (42%), Positives = 24/40 (59%)
Frame = -1
Query: 1170 CLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDACP 1051
C++GG C + ++ LP C CPSG+TG +CE K P
Sbjct: 4383 CMHGGNCYFDETD--LPKCKCPSGYTGKYCEMAFSKGISP 4420
Score = 38.5 bits (88), Expect = 2.2
Identities = 24/83 (28%), Positives = 36/83 (42%), Gaps = 1/83 (1%)
Frame = -1
Query: 627 CEKITATSCHQLECKNGGY-CLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCLHDGN 451
C++I + C + GGY C P S+ T C + + C C+H GN
Sbjct: 4334 CKQICSHLCL---LRPGGYSCACPQGSSFIEGSTTECDAAIELPINLPPPCR--CMHGGN 4388
Query: 450 CTLDEYFEPQCECYQAFIGDRCQ 382
C DE P+C+C + G C+
Sbjct: 4389 CYFDETDLPKCKCPSGYTGKYCE 4411
>gi|32816595|gb|AAP88585.1| glycoprotein receptor gp330/megalin
precursor [Homo sapiens]
Length = 4655
Score = 726 bits (1873), Expect = 0.0
Identities = 543/1819 (29%), Positives = 800/1819 (43%), Gaps = 147/1819 (8%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCT---CNEN-EFRCQ 6403
DE C+ C P F C NG C+ C+ NDC + +DE+ C CN EF C
Sbjct: 2730 DEMESVCALHTCSPTAFTCANGRCVQYSYRCDYYNDCGDGSDEAGCLFRDCNATTEFMCN 2789
Query: 6402 SGACIPSKARCNHMQDCND--ASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKC 6229
+ CIP + CN + +C+D SDE CP R C + G C ++ CI + C
Sbjct: 2790 NRRCIPREFICNGVDNCHDNNTSDEKNCPDRTCQS-------GYTKCHNSNICIPRVYLC 2842
Query: 6228 DGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCA 6049
DG NDC D SDE + +C + ++F C + R C+P+HW CD + DC
Sbjct: 2843 DGDNDCGDNSDENPTYC----------TTHTCSS-SEFQCTSGR-CIPQHWYCDQETDCF 2890
Query: 6048 DGSDEK-NC--DAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDE---HQCETECDS 5887
D SDE +C + C + EF C+ + CIP E CDG DC D DE HQC+ + S
Sbjct: 2891 DASDEPASCGHSERTCLADEFKCDGGR-CIPSEWICDGDNDCGDMSDEDKRHQCQNQNCS 2949
Query: 5886 KGGNATFRCTN-----HRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCA 5722
++ F C N RCIP +W CDG DC D G DE RT C
Sbjct: 2950 ---DSEFLCVNDRPPDRRCIPQSWVCDGDVDCTD-----GYDENQNCTRRTCSENEFTCG 3001
Query: 5721 DETCVVACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASV 5542
C+ CD DC D DE+ C L + C+ N++ C +G+CI +CD
Sbjct: 3002 YGLCIPKI----FRCDRHNDCGDYSDERGC--LYQTCQQNQFTCQNGRCISKTFVCDEDN 3055
Query: 5541 DCVDGSDEWVEICSLSEPPRRGCPSG-WSCLLTNGTIGCLQEQQLCDGRRDCMSGIDE-- 5371
DC DGSDE + +C EP CP + C NG C++ +LC+ DC+ DE
Sbjct: 3056 DCGDGSDELMHLCHTPEPT---CPPHEFKC--DNGR--CIEMMKLCNHLDDCLDNSDEKG 3108
Query: 5370 ----QCDNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKA 5203
+C +P + + CD NC CSC GY L DK+TC+ C +
Sbjct: 3109 CGINECHDP------SISGCDH--NCTDTLTSFYCSCRPGYKLMS-DKRTCVDIDECTEM 3159
Query: 5202 N--CSHFCIDRRDVG-HQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGH 5032
CS C +G + C CAPGY+ + K CR+N IE ++ + L+ TIDG+
Sbjct: 3160 PFVCSQKC--ENVIGSYICKCAPGYLREPDGKTCRQNSNIEPYLIFSNRYYLRNLTIDGY 3217
Query: 5031 AKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINS-LPTKGI 4855
+ +L L N VALD+D +YW D + N+ N +IN LP
Sbjct: 3218 FYSLILEGLDNVVALDFDRVEKRLYWIDTQRQVIER---MFLNKTNKETIINHRLPAA-- 3272
Query: 4854 DGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTP-------LNDPRAIVLDPLQ 4696
+ +AVDW+ R +Y+ D D + V D+ G R+L + ++PR + L P
Sbjct: 3273 ESLAVDWVSRKLYWLDARLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLALHPQY 3332
Query: 4695 ALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIAS 4516
++W DWG A+IGR+ MDG+N+ VI+ + + WPN + +D LY+ DAH YI
Sbjct: 3333 GYLYWADWGHRAYIGRVGMDGTNKSVIISTK-LEWPNGITIDYTNDLLYWADAHLGYIEY 3391
Query: 4515 CNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYR 4336
+ +G R V G++ H FA+ +FED +YW+DW+ T+E+ +K G+NR+ L+ + +R
Sbjct: 3392 SDLEGHHRHTVYDGALPHPFAITIFEDTIYWTDWNTRTVEKGNKYDGSNRQTLV-NTTHR 3450
Query: 4335 PMGFKIVHPSLQSMGSLKTARHPC-SQPARCDNLCIPANTPDLTTSSDNFTCMCAQGFR- 4162
P + HP Q + S +PC + C +LC+ + FTC C FR
Sbjct: 3451 PFDIHVYHPYRQPIVS-----NPCGTNNGGCSHLCL------IKPGGKGFTCECPDDFRT 3499
Query: 4161 ---SEGRSCVSECKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIA 3991
S C+ C F+C KCI WW+ +CP C
Sbjct: 3500 LQLSGSTYCMPMCSSTQFLCANNEKCIPIWWKCDGQKDCSDGSDEL----ALCPQRFCRL 3555
Query: 3990 GQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIP 3811
GQF C + C LC+ ++C G DE+ CEN C +++C + K+CIP
Sbjct: 3556 GQFQC------SDGNCTSPQTLCNAHQNCPDGSDEDRLLCENHHCDSNEWQCAN-KRCIP 3608
Query: 3810 LTSVCDKEKDCDDGSDE--LNCEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQ 3637
+ CD DC+D SDE +C +C+P F C NG +CIP+ + CD ++DC +
Sbjct: 3609 ESWQCDTFNDCEDNSDEDSSHCASRTCRPGQFRCANG----RCIPQAWKCDVDNDCGDHS 3664
Query: 3636 DEP-DSCFGIGEC--THEQFQC-TSGKCIPKRRQCDGTLDCRDGSDEKGC-KKECAIVCD 3472
DEP + C +F C T+ +CIPK C+G DCRD SDE+GC ++ C V D
Sbjct: 3665 DEPIEECMSSAHLCDNFTEFSCKTNYRCIPKWAVCNGVDDCRDNSDEQGCEERTCHPVGD 3724
Query: 3471 -----NSCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKE----NRKC--GGFACDGIV 3325
+ C+ CDG+ C D S DEE C ++ E E N++C + CD
Sbjct: 3725 FRCKNHHCIPLRWQCDGQNDCGDNS--DEENCAPRECTESEFRCVNQQCIPSRWICDHYN 3782
Query: 3324 DCEDGSDEKGCPDLECH---------LASNKSLICDGTIDCSSGKDENNCHNN------G 3190
DC D SDE+ C CH + L CDG+ DC DE +C
Sbjct: 3783 DCGDNSDERDCEMRTCHPEYFQCTSGHCVHSELKCDGSADCLDASDEADCPTRFPDGAYC 3842
Query: 3189 ESNFFQCSMQT-IKEWQVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCLDVST 3013
++ F+C I + CDG DC DG DE +C CD+ + C+ S
Sbjct: 3843 QATMFECKNHVCIPPYWKCDGDDDCGDGSDEELHLCLDVPCNSPNRFRCDNNR-CI-YSH 3900
Query: 3012 ALCDGIRDCFDGSDENPIHC-----KDMCKGKYRCTNGRCI-------DVSARXXXXXXX 2869
+C+G+ DC DG+DE HC K + +Y+C NG CI D
Sbjct: 3901 EVCNGVDDCGDGTDETEEHCRKPTPKPCTEYEYKCGNGHCIPHDNVCDDADDCGDWSDEL 3960
Query: 2868 XXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFI 2689
AE +C Q C C C G+ D C +++ E F
Sbjct: 3961 GCNKGKERTCAE----NICEQNCTQLNEGGFICSCTAGFETNVFDRTSCLDINE-CEQFG 4015
Query: 2688 TNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRS 2509
T H + + S V F M+ PG + L+ + + ++ S
Sbjct: 4016 TCPQ--HCRNTKGSYECVCADGFT-SMSDRPGK-RCAAEGSSPLLLLPDNVRIRKYNLSS 4071
Query: 2508 KKWSDGLIGSWGEEESTAGLITYDFMHNN-----VYFTESSEQNR--------------- 2389
+++S+ L ++E + YD+ + VY+T E +R
Sbjct: 4072 ERFSEYL-----QDEEYIQAVDYDWDPXDIGLSVVYYTVRGEGSRFGAIKRAYIPNFESG 4126
Query: 2388 -------------------GVLFD-----------RQANIYVAKAKDTSTRTLIVNSTGT 2299
G+ D + I VAK + LI
Sbjct: 4127 RNNLVQEVDLKLKYVMQPDGIAVDWVGRHIYWSDVKNKRIEVAKLDGRYRKWLISTDLDQ 4186
Query: 2298 INSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMV 2119
++AV+P L+FWT P+ SA ++G + LV ++ PT +
Sbjct: 4187 PAAIAVNPKLGLMFWTDWGKEPKXESAWMNG-----------EDRNILVFEDLGWPTGLS 4235
Query: 2118 LDF-SNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITRQ-GS 1945
+D+ +N+R+YW D + IET+ +DG DRR + K + P ++D+ +Y I+++ G
Sbjct: 4236 IDYLNNDRIYWSDFKEDVIETIKYDGTDRRVIAKEAM--NPYSLDIFEDQLYWISKEKGE 4293
Query: 1944 IHRMHKFTGKTNKYVQKIREVSPRI-QIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCV 1768
+ + +KF G+ K +K V+P + Q+R+ H ++ S K C S C
Sbjct: 4294 VWKQNKF-GQGKK--EKTLVVNPWLTQVRIFHQLRYNKSVPNLCKQIC-SHLC------- 4342
Query: 1767 PDQDKNGILIP---KCLCGPG-RFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCSPQK 1600
+L P C C G F E ST +C E C + C +
Sbjct: 4343 -------LLRPGGYSCACPQGSSFIEGSTTECDAAIELPINLPP--PCRCMHGGNCYFDE 4393
Query: 1599 T----CVCPPGFYGRQCEI 1555
T C CP G+ G+ CE+
Sbjct: 4394 TDLPKCKCPSGYTGKYCEM 4412
Score = 371 bits (952), Expect = e-100
Identities = 260/820 (31%), Positives = 381/820 (45%), Gaps = 17/820 (2%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC-----TCNENEFR 6409
+ + T T C F C NG C+P +C+ ++DC + +DE C TC+ + F
Sbjct: 1014 EGDPTNEPPTEQCGLFSFPCKNGRCVPNYYLCDGVDDCHDNSDEQLCGTLNNTCSSSAFT 1073
Query: 6408 CQSGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKC 6229
C G CIP+ RC+ DC D SDE CP ++ + T QCI +W C
Sbjct: 1074 CGHGECIPAHWRCDKRNDCVDGSDEHNCPTHAPASCLDTQYT-----CDNHQCISKNWVC 1128
Query: 6228 DGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCA 6049
D NDC DGSDEK+C ++ +C +QF C C+ + CDG DC
Sbjct: 1129 DTDNDCGDGSDEKNC-----------NSTETCQ-PSQFNC-PNHRCIDLSFVCDGDKDCV 1175
Query: 6048 DGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNAT 5869
DGSDE C CT+ +F C S KCI + +CDG DC D DE C T +
Sbjct: 1176 DGSDEVGC-VLNCTASQFKCASGDKCIGVTNRCDGVFDCSDNSDEAGCPTRPPGMCHSDE 1234
Query: 5868 FRCTNHR-CIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACEL 5692
F+C CIP W CDG DC+ GSDE + +T C + C+
Sbjct: 1235 FQCQEDGICIPNFWECDGHPDCL-----YGSDEHNACVPKTCPSSYFHCDNGNCI----H 1285
Query: 5691 TAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMC-DSGQCIDSGRLCDASVDCVDGSDEW 5515
LCD DC D DEK+C + +C +W C C++ +CD DC +G+DE
Sbjct: 1286 RXWLCDRDNDCGDMSDEKDCPTQPFRCPSWQWQCLGHNICVNLSVVCDGIFDCPNGTDE- 1344
Query: 5514 VEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSST 5335
+C +G SC NG GC E C+ + N C
Sbjct: 1345 SPLC-----------NGNSCSDFNG--GCTHECVQEPFGAKCLCPLGFLLANDSKTCEDI 1391
Query: 5334 RNSCDQTWNCQRHA----GFESCSCDDGYHLSPYDKKTCLRSPSCPKANCSHFCIDRRDV 5167
+ CD +C +H G CSCD GY L D +TC K S +
Sbjct: 1392 -DECDILGSCSQHCYNMRGSFRCSCDTGYMLES-DGRTC-------KVTASESLL----- 1437
Query: 5166 GHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLTNGVAL 4987
+ S+N+ D++ +++ +Y +L+ N + VA+
Sbjct: 1438 --------LLVASQNKIIA---DSVTSQVHNIY---------------SLVENGSYIVAV 1471
Query: 4986 DYDVKSDLVYWTDVAHDGNKAGITSMSNQPNT-YRVINSLPTKGIDGIAVDWLGRNIYYT 4810
D+D S ++W+D G T + Q T RV+ + IA+DW+GRN+Y+T
Sbjct: 1472 DFDSISGRIFWSDATQ-----GKTWSAFQNGTDRRVVFDSSIILTETIAIDWVGRNLYWT 1526
Query: 4809 DRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPL--QALVFWTDWGASAHIGRMNMD 4636
D + I V + G +L+ L +PR + LDP + L+FW+DWG I R +MD
Sbjct: 1527 DYALETIEVSKIDGSHRTVLISKN-LTNPRGLALDPRMNEHLLFWSDWGHHPRIERASMD 1585
Query: 4635 GSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGS--VRH 4462
GS VI+QD+ I WP L +D P + LYF D++ DY+ C+Y+G RR V+ +RH
Sbjct: 1586 GSMRTVIVQDK-IFWPCGLTIDYPNRLLYFMDSYLDYMDFCDYNGHHRRQVIASDLIIRH 1644
Query: 4461 IFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLK 4282
+AL +FED VYW+D + R +K G N+ V++ + Q+ P+G VHPS Q
Sbjct: 1645 PYALTLFEDSVYWTDRATRRVMRANKWHGGNQSVVMYNIQW-PLGIVAVHPSKQ-----P 1698
Query: 4281 TARHPCSQPARCDNLCIPANTPDLTTSSDNF-TCMCAQGF 4165
+ +PC+ +RC +LC+ L++ +F +C+C G+
Sbjct: 1699 NSVNPCAF-SRCSHLCL------LSSQGPHFYSCVCPSGW 1731
Score = 351 bits (900), Expect = 2e-94
Identities = 428/1791 (23%), Positives = 679/1791 (37%), Gaps = 184/1791 (10%)
Frame = -1
Query: 5247 YDKKTCLRSPS------CPKAN--CSHFCIDRRDVGH-QCFCAPGYILSENQKDCRRNDT 5095
+DK+ RSP+ C + N CSH C + +C CA G + S+ +N
Sbjct: 2329 FDKQVQPRSPAEVNNNPCLENNGGCSHLCFALPGLHTPKCDCAFGTLQSDG-----KNCA 2383
Query: 5094 IEAEILMVYGHRLKLFTI----DGHAKATLLSNLTNGV-ALDYDVKSDLVYWT-DVAHDG 4933
I E +++ L ++ + H+ N+ V +LDYD SD +Y+T ++A
Sbjct: 2384 ISTENFLIFALSNSLRSLHLDPENHSPPFQTINVERTVMSLDYDSVSDRIYFTQNLASGV 2443
Query: 4932 NKAGITSMSNQPNTYRVINSLPTKGI---DGIAVDWLGRNIYYTDRNHDAIAVCDMRGRF 4762
+ ++S+ +T VI S GI DGIA DW+ R IYY+D + I G
Sbjct: 2444 GQISYATLSSGIHTPTVIAS----GIGTADGIAFDWITRRIYYSDYLNQMINSMAEDGS- 2498
Query: 4761 NRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNA 4582
NR ++ P PRAIVLDP Q ++W DW A I R + G N +V + + ++ P+
Sbjct: 2499 NRTVIARVP--KPRAIVLDPCQGYLYWADWDTHAKIERATL-GGNFRVPIVNSSLVMPSG 2555
Query: 4581 LAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHT 4402
L +D LY+ DA I G R +++ +V H F L ++ Y+YW+D +
Sbjct: 2556 LTLDYEEDLLYWVDASLQRIERSTLTGVDREVIVNAAV-HAFGLTLYGQYIYWTDLYTQR 2614
Query: 4401 IERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPAR-----CDNL 4237
I R +K G+ + + + +P G V +K + C+ P C ++
Sbjct: 2615 IYRANKYDGSGQIAMTTNLLSQPRGINTV---------VKNQKQQCNNPCEQFNGGCSHI 2665
Query: 4236 CIPANTPDLTTSSDNFTCMCAQG----FRSEGRSCVSE----CKPNDFVCTKTYKCISSW 4081
C P + C C + + C+ + C + F C+ +CIS
Sbjct: 2666 CAPG--------PNGAECQCPHEGNWYLANNRKHCIVDNGERCGASSFTCSNG-RCISEE 2716
Query: 4080 WRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCS 3901
W+ +E VC C F C A +C+ S CD DC
Sbjct: 2717 WKCDNDNDCGDGSDE---MESVCALHTCSPTAFTC------ANGRCVQYSYRCDYYNDCG 2767
Query: 3900 GGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDG--SDELNCEITSCKPD 3727
G DE + T +F C +++ CIP +C+ +C D SDE NC +C+
Sbjct: 2768 DGSDEAGCLFRDCNAT-TEFMCNNRR-CIPREFICNGVDNCHDNNTSDEKNCPDRTCQSG 2825
Query: 3726 FFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQ 3547
+ C N CIP+ + CDG++DC + DE + C+ +FQCTSG+CIP+
Sbjct: 2826 YTKCHNSNI---CIPRVYLCDGDNDCGDNSDENPTYCTTHTCSSSEFQCTSGRCIPQHWY 2882
Query: 3546 CDGTLDCRDGSDEKGC----KKECA---IVCDNS-CVHADDLCDGKKKCNDGSDEDEE-A 3394
CD DC D SDE ++ C CD C+ ++ +CDG C D SDED+
Sbjct: 2883 CDQETDCFDASDEPASCGHSERTCLADEFKCDGGRCIPSEWICDGDNDCGDMSDEDKRHQ 2942
Query: 3393 CVIKQLLEKE---------NRKC--GGFACDGIVDCEDGSDE-KGCPDLECH-------- 3274
C + + E +R+C + CDG VDC DG DE + C C
Sbjct: 2943 CQNQNCSDSEFLCVNDRPPDRRCIPQSWVCDGDVDCTDGYDENQNCTRRTCSENEFTCGY 3002
Query: 3273 -LASNKSLICDGTIDCSSGKDENNC-HNNGESNFFQCSM-QTIKEWQVCDGRWDCADGLD 3103
L K CD DC DE C + + N F C + I + VCD DC DG D
Sbjct: 3003 GLCIPKIFRCDRHNDCGDYSDERGCLYQTCQQNQFTCQNGRCISKTFVCDEDNDCGDGSD 3062
Query: 3102 ESPEMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDE-----NPIHCKDMCK 2938
E +C + + C + D +C+++ LC+ + DC D SDE N H +
Sbjct: 3063 ELMHLCHTPEPTCPPHEFKCDNGRCIEMMK-LCNHLDDCLDNSDEKGCGINECHDPSISG 3121
Query: 2937 GKYRCTNGRCIDVSARXXXXXXXXXXXXXXXXGAECHHFG-VCAQKCWMAFNHTARCHCA 2761
+ CT+ EC VC+QKC C CA
Sbjct: 3122 CDHNCTD-TLTSFYCSCRPGYKLMSDKRTCVDIDECTEMPFVCSQKCENVIGSYI-CKCA 3179
Query: 2760 PGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDF 2581
PGY R + D C + + E ++ NR +L +L ++ +++ + + +
Sbjct: 3180 PGYLR-EPDGKTCRQ-NSNIEPYLIFSNRYYLRNL-----TIDGYFYSLILEGLDNVVAL 3232
Query: 2580 GYDVFRTTLMYTVGIGNSRVD--IRSKKWSDGLIGSWGEEESTAGLITYDFMHNNVYFTE 2407
+D L Y + ++ +K + +I A + D++ +Y+ +
Sbjct: 3233 DFDRVEKRL-YWIDTQRQVIERMFLNKTNKETII---NHRLPAAESLAVDWVSRKLYWLD 3288
Query: 2406 SSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINS--------LAVDPIKRLIFWT 2251
+ R ++V+ R L + N+ LA+ P ++W
Sbjct: 3289 A----------RLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLYWA 3338
Query: 2250 TSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKR 2071
I +DG ++ + P + +D++N+ LYW D
Sbjct: 3339 DWGHRAYIGRVGMDG-----------TNKSVIISTKLEWPNGITIDYTNDLLYWADAHLG 3387
Query: 2070 TIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGKTNKYVQK 1894
IE +G R TV L P + + IY ++ + +K+ G + +
Sbjct: 3388 YIEYSDLEGHHRHTVYDGAL-PHPFAITIFEDTIYWTDWNTRTVEKGNKYDGSNRQTL-- 3444
Query: 1893 IREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLCGPG 1714
+ I V HP + + NPC ++ + +C+ G C C P
Sbjct: 3445 VNTTHRPFDIHVYHPYRQPI-----VSNPCGTNNGGCSHLCLIKPGGKGF---TCEC-PD 3495
Query: 1713 RFFEVSTKKCMQLREKDQEASQCG--DYFCYNNAGCSP-------QKTC--------VCP 1585
F + +QL C + C NN C P QK C +CP
Sbjct: 3496 DF------RTLQLSGSTYCMPMCSSTQFLCANNEKCIPIWWKCDGQKDCSDGSDELALCP 3549
Query: 1584 PGFYGRQCEINECSETCWNGETCAVQEFGSTTNVVCHCP--SNYTQSSCATNVCEGVCGP 1411
F C + + C +G + Q + N +CP S+ + C + C+
Sbjct: 3550 QRF----CRLGQFQ--CSDGNCTSPQ---TLCNAHQNCPDGSDEDRLLCENHHCD---SN 3597
Query: 1410 RGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHKADAKVCYGHCFSGGACDGEGPLNL 1231
C C + C +++ CE + HC + + C +G ++
Sbjct: 3598 EWQCANKRCIPESWQCDTFNDCEDNSDEDSSHCASRT-CRPGQFRCANGRCIPQAWKCDV 3656
Query: 1230 RCSCGDGLTGNRCQNCV--GHECLNGGFCSYANSNRSLPHCI-------CPSGFTGDHCE 1078
CGD + + C+ H C N S + R +P C CE
Sbjct: 3657 DNDCGDH-SDEPIEECMSSAHLCDNFTEFSCKTNYRCIPKWAVCNGVDDCRDNSDEQGCE 3715
Query: 1077 EYLCKDACPFGSKCTYDITKPMDPITCSCE-QNAAAHNTD---CSP--------ICQKQ- 937
E C F K + I P+ C+ QN N+D C+P C Q
Sbjct: 3716 ERTCHPVGDFRCKNHHCI-----PLRWQCDGQNDCGDNSDEENCAPRECTESEFRCVNQQ 3770
Query: 936 ---PNW-CHNGGRCLDTPGYPGKCK---CLPRF----------AGPRCDVPVQCDDYCTN 808
W C + C D C+ C P + + +CD C D ++
Sbjct: 3771 CIPSRWICDHYNDCGDNSD-ERDCEMRTCHPEYFQCTSGHCVHSELKCDGSADCLD-ASD 3828
Query: 807 NSKC-------TITNGTHFECD---CKPGFKGLRCEQETKCSECSNEA--KCIKKPSGT- 667
+ C T FEC C P + +C+ + C + S+E C+ P +
Sbjct: 3829 EADCPTRFPDGAYCQATMFECKNHVCIPPY--WKCDGDDDCGDGSDEELHLCLDVPCNSP 3886
Query: 666 --------------VIC----QCPQGLG--GEYCEKITATSCHQLECKNG-GYCLKPD-- 556
+C C G E+C K T C + E K G G+C+ D
Sbjct: 3887 NRFRCDNNRCIYSHEVCNGVDDCGDGTDETEEHCRKPTPKPCTEYEYKCGNGHCIPHDNV 3946
Query: 555 ----PSANRTSPTCLCSPGFKGLLCSSNACENFC--LHDGN--CTLDEYFE 427
S C+ G K C+ N CE C L++G C+ FE
Sbjct: 3947 CDDADDCGDWSDELGCNKG-KERTCAENICEQNCTQLNEGGFICSCTAGFE 3996
Score = 319 bits (817), Expect = 7e-85
Identities = 220/724 (30%), Positives = 333/724 (45%), Gaps = 16/724 (2%)
Frame = -1
Query: 6261 TSQCIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPK 6082
+ CI W+CDGT DC D +DE C V G F C + C+P
Sbjct: 37 SGHCIPADWRCDGTKDCSDDADEIGCAVVTCQQG-------------YFKCQSEGQCIPS 83
Query: 6081 HWQCDGQPDCADGSDEK-NCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQC 5905
W CD DC DGSDE+ +C C+S + +C S+ +CIP E +CD RDCPDG DE+ C
Sbjct: 84 SWVCDQDQDCDDGSDERQDCSQSTCSSHQITC-SNGQCIPSEYRCDHVRDCPDGADENDC 142
Query: 5904 E-TECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSR 5728
+ C+ C N C + +CD DC D+ SDE++C H
Sbjct: 143 QYPTCEQ------LTCDNGACYNTSQKCDWKVDCRDS-----SDEINCT--EICLHNEFS 189
Query: 5727 CADETCVVACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDA 5548
C + C+ A +CD DC DG DE C C ++ C SG+CI +CD
Sbjct: 190 CGNGECIP----RAYVCDHDNDCQDGSDEHACNY--PTCGGYQFTCPSGRCIYQNWVCDG 243
Query: 5547 SVDCVDGSDEWVEICSLSEPPRRGC-PSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDE 5371
DC D DE + C C P WSC + C+ ++CDG DC DE
Sbjct: 244 EDDCKDNGDE--DGCESGPHDVHKCSPREWSCPESG---RCISIYKVCDGILDCPGREDE 298
Query: 5370 QCDNPQGNCSSTR-NSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCP-KANC 5197
+ CS T ++ + + C +C C GY ++ D +TC+ C C
Sbjct: 299 NNTSTGKYCSMTLCSALNCQYQCHETPYGGACFCPPGYIINHNDSRTCVEFDDCQIWGIC 358
Query: 5196 SHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTI-EAEILMVYGHRLKLFTIDGHAKAT 5020
C + R H C C GYIL Q C+ ND+ EA I+ G L + I G +
Sbjct: 359 DQKC-ESRPGRHLCHCEEGYILERGQY-CKANDSFGEASIIFSNGRDLLIGDIHGRSFRI 416
Query: 5019 LLSNLTNGVALD--YDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGI 4846
L+ + GVA+ + V+WTD NK + N N V+N + + + +
Sbjct: 417 LVESQNRGVAVGVAFHYHLQRVFWTDTVQ--NKVFSVDI-NGLNIQEVLN-VSVETPENL 472
Query: 4845 AVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDW-- 4672
AVDW+ IY + + I + ++ G + R+ L L PR I +DP +F++DW
Sbjct: 473 AVDWVNNKIYLVETKVNRIDMVNLDGSY-RVTLITENLGHPRGIAVDPTVGYLFFSDWES 531
Query: 4671 -GASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSK 4495
+ R MDGSN + +++ + + WP + +D ++R+Y+ D+ DYI + YDG +
Sbjct: 532 LSGEPKLERAFMDGSNRKDLVKTK-LGWPAGVTLDMISKRVYWVDSRFDYIETVTYDGIQ 590
Query: 4494 RRMVLRGS--VRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFK 4321
R+ V+ G + H F +++FE V+++DW + + +K T TN +V Q RP G
Sbjct: 591 RKTVVHGGSLIPHPFGVSLFEGQVFFTDWTKMAVLKANKFTETNPQVYYQ-ASLRPYGVT 649
Query: 4320 IVHPSLQSMGSLKTARHPC-SQPARCDNLCIPANTPDLTTSSDNFTCMCAQGFR--SEGR 4150
+ H Q A +PC C+ +C+ ++ D F C C GF+ ++ R
Sbjct: 650 VYHSLRQPY-----ATNPCKDNNGGCEQVCVLSHRTD--NDGLGFRCKCTFGFQLDTDER 702
Query: 4149 SCVS 4138
C++
Sbjct: 703 HCIA 706
Score = 287 bits (735), Expect = 2e-75
Identities = 237/840 (28%), Positives = 363/840 (43%), Gaps = 63/840 (7%)
Frame = -1
Query: 5250 PYDKKTCLRSPSCPKANCSHFCI-----DRRDVGHQCFCAPGYILSENQKDCR--RNDTI 5092
PY C + C C+ D +G +C C G+ L +++ C +N I
Sbjct: 657 PYATNPCKDN----NGGCEQVCVLSHRTDNDGLGFRCKCTFGFQLDTDERHCIAVQNFLI 712
Query: 5091 EAEILMVYGHRLKLFTIDGHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITS 4912
+ + + G L T + + N + V +D+D + ++++D++ K I
Sbjct: 713 FSSQVAIRGIPFTLSTQED-VMVPVSGNPSFFVGIDFDAQDSTIFFSDMS----KHMIFK 767
Query: 4911 MSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPL 4732
++ + + ++ +A DW+ +N+Y+TD ++ +I+V + + R +++ L
Sbjct: 768 QKIDGTGREILAANRVENVESLAFDWISKNLYWTDSHYKSISVMRLADKTRRTVVQY--L 825
Query: 4731 NDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRL 4552
N+PR++V+ P +F+TDW A I R DGS+ ++ + T+ WPN LA+D A RL
Sbjct: 826 NNPRSVVVHPFAGYLFFTDWFRPAKIMRAWSDGSHLLPVI-NTTLGWPNGLAIDWAASRL 884
Query: 4551 YFGDAHRDYIASCNYDG-SKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITG 4375
Y+ DA+ D I +DG +RR+ + H F LA+F ++++++DW I RV K G
Sbjct: 885 YWVDAYFDKIEHSTFDGLDRRRLGHIEQMTHPFGLAIFGEHLFFTDWRLGAIIRVRKADG 944
Query: 4374 TNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPAR----CDNLCIPANTPDLT 4207
V+ Y I+H + +++T + C+QP C + C P
Sbjct: 945 GEMTVIRSGIAY------ILHLKSYDV-NIQTGSNACNQPTHPNGDCSHFCFPV------ 991
Query: 4206 TSSDNF--TCMCAQGFRSEGRSCVSECKPND-----------FVCTKTYKCISSWWRXXX 4066
NF C C G R E P + F C K +C+ +++
Sbjct: 992 ---PNFQRVCGCPYGMRLASNHLTCEGDPTNEPPTEQCGLFSFPC-KNGRCVPNYYLCDG 1047
Query: 4065 XXXXXXXXXXGYFVEGVCPPF--PCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGD 3892
E +C C + F CG +C+ A CD DC G
Sbjct: 1048 VDDCHDNSD-----EQLCGTLNNTCSSSAFTCGH------GECIPAHWRCDKRNDCVDGS 1096
Query: 3891 DEE--PAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEIT-SCKPDFF 3721
DE P C + Q+ C D +CI VCD + DC DGSDE NC T +C+P F
Sbjct: 1097 DEHNCPTHAP-ASCLDTQYTC-DNHQCISKNWVCDTDNDCGDGSDEKNCNSTETCQPSQF 1154
Query: 3720 ACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSG-KCIPKRRQC 3544
C N +CI F CDG+ DC +G DE + CT QF+C SG KCI +C
Sbjct: 1155 NCPN----HRCIDLSFVCDGDKDCVDGSDEVGC---VLNCTASQFKCASGDKCIGVTNRC 1207
Query: 3543 DGTLDCRDGSDEKGCKKECAIVC---------DNSCVHADDLCDGKKKCNDGSDEDEEAC 3391
DG DC D SDE GC +C D C+ CDG C GSDE AC
Sbjct: 1208 DGVFDCSDNSDEAGCPTRPPGMCHSDEFQCQEDGICIPNFWECDGHPDCLYGSDE-HNAC 1266
Query: 3390 VIK----QLLEKENRKC--GGFACDGIVDCEDGSDEKGCPD------------LECHLAS 3265
V K +N C + CD DC D SDEK CP L ++
Sbjct: 1267 VPKTCPSSYFHCDNGNCIHRXWLCDRDNDCGDMSDEKDCPTQPFRCPSWQWQCLGHNICV 1326
Query: 3264 NKSLICDGTIDCSSGKDENN-CHNNGESNF-FQCSMQTIKEWQVCDGRWDCADGLDESPE 3091
N S++CDG DC +G DE+ C+ N S+F C+ + ++E
Sbjct: 1327 NLSVVCDGIFDCPNGTDESPLCNGNSCSDFNGGCTHECVQE------------------- 1367
Query: 3090 MCASRKARCF-RIGY--CDDKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKGKYRCT 2920
A+C +G+ +D K C D+ CD + C HC +M +G +RC+
Sbjct: 1368 ---PFGAKCLCPLGFLLANDSKTCEDIDE--CDILGSCSQ-------HCYNM-RGSFRCS 1414
Score = 228 bits (581), Expect = 2e-57
Identities = 215/806 (26%), Positives = 322/806 (39%), Gaps = 30/806 (3%)
Frame = -1
Query: 3999 CIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKK 3820
C + F CG + C+ A CDG KDCS DD + C C + FKC + +
Sbjct: 28 CDSAHFRCG------SGHCIPADWRCDGTKDCS--DDADEIGCAVVTCQQGYFKCQSEGQ 79
Query: 3819 CIPLTSVCDKEKDCDDGSDE-LNCEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPE 3643
CIP + VCD+++DCDDGSDE +C ++C C NG +CIP E+ CD DCP+
Sbjct: 80 CIPSSWVCDQDQDCDDGSDERQDCSQSTCSSHQITCSNG----QCIPSEYRCDHVRDCPD 135
Query: 3642 GQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQCDGTLDCRDGSDEKGCKKEC---AIVCD 3472
G DE D + T EQ C +G C ++CD +DCRD SDE C + C C
Sbjct: 136 GADENDCQYP----TCEQLTCDNGACYNTSQKCDWKVDCRDSSDEINCTEICLHNEFSCG 191
Query: 3471 N-SCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKENRKCGGFACDGIVDCEDGSDEKG 3295
N C+ +CD C DGS DE AC CGG+ +
Sbjct: 192 NGECIPRAYVCDHDNDCQDGS--DEHAC--------NYPTCGGY-------------QFT 228
Query: 3294 CPDLECHLASNKSLICDGTIDCSSGKDENNCHNNGESNFFQCSM---------QTIKEWQ 3142
CP C ++ +CDG DC DE+ C +G + +CS + I ++
Sbjct: 229 CPSGRC---IYQNWVCDGEDDCKDNGDEDGC-ESGPHDVHKCSPREWSCPESGRCISIYK 284
Query: 3141 VCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDENP 2962
VCDG DC DE+ YC S LC + +C E P
Sbjct: 285 VCDGILDCPGREDENNTSTGK---------YC---------SMTLCSAL-NCQYQCHETP 325
Query: 2961 IHCKDMCKGKYRCTNG---RCIDVSARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMA 2791
C Y + C++ +C +G+C QKC
Sbjct: 326 YGGACFCPPGYIINHNDSRTCVEFD--------------------DCQIWGICDQKCESR 365
Query: 2790 FNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQVSVLRPVFNIK 2611
CHC GY + + A + +NG L + + +L N
Sbjct: 366 PGRHL-CHCEEGYILERGQYCKANDSFGEASIIFSNGRDLLIGDIHGRSFRILVESQN-- 422
Query: 2610 MNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGLITYDFM 2431
+ G+ F Y + R TV VDI + L S E+ A D++
Sbjct: 423 -RGVAVGVAFHYHLQRVFWTDTVQNKVFSVDINGLNIQEVLNVSVETPENLA----VDWV 477
Query: 2430 HNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIF-- 2257
+N +Y E ++ NR + + + V TLI + G +AVDP +F
Sbjct: 478 NNKIYLVE-TKVNRIDMVNLDGSYRV---------TLITENLGHPRGIAVDPTVGYLFFS 527
Query: 2256 -WTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDV 2080
W + + P++ A +DG K LV+ + P + LD ++R+YW+D
Sbjct: 528 DWESLSGEPKLERAFMDG-----------SNRKDLVKTKLGWPAGVTLDMISKRVYWVDS 576
Query: 2079 LKRTIETVSFDGRDRRT-VRKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGKTNK 1906
IETV++DG R+T V L P + + G ++ + ++ + +KFT
Sbjct: 577 RFDYIETVTYDGIQRKTVVHGGSLIPHPFGVSLFEGQVFFTDWTKMAVLKANKFT----- 631
Query: 1905 YVQKIREVSPRIQIRVA-HPAKHTVSHITHQ---KNPCQSDYCPSNTVCV----PDQDKN 1750
E +P++ + + P TV H Q NPC+ + VCV D D
Sbjct: 632 ------ETNPQVYYQASLRPYGVTVYHSLRQPYATNPCKDNNGGCEQVCVLSHRTDNDGL 685
Query: 1749 GILIPKCLCGPGRFFEVSTKKCMQLR 1672
G +C C G + + C+ ++
Sbjct: 686 GF---RCKCTFGFQLDTDERHCIAVQ 708
Score = 212 bits (539), Expect = 1e-52
Identities = 221/833 (26%), Positives = 323/833 (38%), Gaps = 57/833 (6%)
Frame = -1
Query: 4005 FPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDK 3826
FP Q VCG C Y +L C G EP +C F C +
Sbjct: 989 FPVPNFQRVCG---------CPYGMRLASNHLTCEGDPTNEPP---TEQCGLFSFPCKNG 1036
Query: 3825 KKCIPLTSVCDKEKDCDDGSDELNCEI--TSCKPDFFACFNGTAISKCIPKEFYCDGEDD 3652
+ C+P +CD DC D SDE C +C F C +G +CIP + CD +D
Sbjct: 1037 R-CVPNYYLCDGVDDCHDNSDEQLCGTLNNTCSSSAFTCGHG----ECIPAHWRCDKRND 1091
Query: 3651 CPEGQDEPDS-CFGIGECTHEQFQCTSGKCIPKRRQCDGTLDCRDGSDEKGCK-----KE 3490
C +G DE + C Q+ C + +CI K CD DC DGSDEK C +
Sbjct: 1092 CVDGSDEHNCPTHAPASCLDTQYTCDNHQCISKNWVCDTDNDCGDGSDEKNCNSTETCQP 1151
Query: 3489 CAIVCDNS-CVHADDLCDGKKKCNDGSDEDEEA--CVIKQLLEKENRKCGGFA--CDGIV 3325
C N C+ +CDG K C DGSDE C Q KC G CDG+
Sbjct: 1152 SQFNCPNHRCIDLSFVCDGDKDCVDGSDEVGCVLNCTASQFKCASGDKCIGVTNRCDGVF 1211
Query: 3324 DCEDGSDEKGCPDLE---CH----------LASNKSLICDGTIDCSSGKDENNC--HNNG 3190
DC D SDE GCP CH + CDG DC G DE+N
Sbjct: 1212 DCSDNSDEAGCPTRPPGMCHSDEFQCQEDGICIPNFWECDGHPDCLYGSDEHNACVPKTC 1271
Query: 3189 ESNFFQCSM-QTIKEWQVCDGRWDCADGLDESPEMCASRKARCFRIGY-CDDKKQCLDVS 3016
S++F C I +CD DC D DE C ++ RC + C C+++S
Sbjct: 1272 PSSYFHCDNGNCIHRXWLCDRDNDCGDMSDEKD--CPTQPFRCPSWQWQCLGHNICVNLS 1329
Query: 3015 TALCDGIRDCFDGSDENPI----HCKDMCKGKYRCTNGRCID----VSARXXXXXXXXXX 2860
+CDGI DC +G+DE+P+ C D G CT+ C+
Sbjct: 1330 V-VCDGIFDCPNGTDESPLCNGNSCSDFNGG---CTH-ECVQEPFGAKCLCPLGFLLAND 1384
Query: 2859 XXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECE-PLSKSAEMFITN 2683
EC G C+Q C+ + RC C GY ++D C+ S+S + + +
Sbjct: 1385 SKTCEDIDECDILGSCSQHCYN-MRGSFRCSCDTGYM-LESDGRTCKVTASESLLLLVAS 1442
Query: 2682 GNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKK 2503
N++ SV V NI +L+ G Y V + + R
Sbjct: 1443 QNKI-------IADSVTSQVHNI-YSLVENG------------SYIVAVDFDSISGRIF- 1481
Query: 2502 WSDGLIG-SWGEEESTAG-------------LITYDFMHNNVYFTESSEQNRGVLFDRQA 2365
WSD G +W ++ I D++ N+Y+T+ + +
Sbjct: 1482 WSDATQGKTWSAFQNGTDRRVVFDSSIILTETIAIDWVGRNLYWTDYALET--------- 1532
Query: 2364 NIYVAKAKDTSTRTLIVNSTGTINSLAVDPI--KRLIFWTTSAPVPRILSANLDGKPIAQ 2191
I V+K + LI + LA+DP + L+FW+ PRI A++DG
Sbjct: 1533 -IEVSKIDGSHRTVLISKNLTNPRGLALDPRMNEHLLFWSDWGHHPRIERASMDG----- 1586
Query: 2190 PFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFEL 2011
+V+ IF P + +D+ N LY++D ++ ++G RR V +L
Sbjct: 1587 ------SMRTVIVQDKIFWPCGLTIDYPNRLLYFMDSYLDYMDFCDYNGHHRRQVIASDL 1640
Query: 2010 -GDTPVTMDVLGGYIYLITR-QGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHT 1837
P + + +Y R + R +K+ G V + + + I HP+K
Sbjct: 1641 IIRHPYALTLFEDSVYWTDRATRRVMRANKWHGGNQSVV--MYNIQWPLGIVAVHPSKQ- 1697
Query: 1836 VSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQ 1678
+ NPC C + +C+ G C+C G C++
Sbjct: 1698 ----PNSVNPCAFSRC--SHLCL--LSSQGPHFYSCVCPSGWSLSPDLLNCLR 1742
Score = 153 bits (387), Expect = 5e-35
Identities = 105/320 (32%), Positives = 144/320 (44%), Gaps = 34/320 (10%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC---TCNENEFRCQ 6403
D+ D + C+ R C F C N CIP + +C+ NDC + +DE +C TC+ F+C
Sbjct: 3747 DNSDEENCAPRECTESEFRCVNQQCIPSRWICDHYNDCGDNSDERDCEMRTCHPEYFQCT 3806
Query: 6402 SGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDG 6223
SG C+ S+ +C+ DC DASDE CP R + + C CI P WKCDG
Sbjct: 3807 SGHCVHSELKCDGSADCLDASDEADCPTRFPD--GAYCQATMFEC-KNHVCIPPYWKCDG 3863
Query: 6222 TNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADG 6043
+DC DGSDE + + D C++ +F C R C+ H C+G DC DG
Sbjct: 3864 DDDCGDGSDE-ELHLCLDV---------PCNSPNRFRCDNNR-CIYSHEVCNGVDDCGDG 3912
Query: 6042 SD--EKNC---DAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGED------------- 5917
+D E++C K CT +E+ C + CIP + CD DC D D
Sbjct: 3913 TDETEEHCRKPTPKPCTEYEYKC-GNGHCIPHDNVCDDADDCGDWSDELGCNKGKERTCA 3971
Query: 5916 EHQCETECDS-KGGNATFRCT---------NHRCIPMAWRCDGTDDCMDNAKSL-GSDEV 5770
E+ CE C G CT C+ + C+ C + ++ GS E
Sbjct: 3972 ENICEQNCTQLNEGGFICSCTAGFETNVFDRTSCLDIN-ECEQFGTCPQHCRNTKGSYEC 4030
Query: 5769 DCAAGRTSF--HVPSRCADE 5716
CA G TS RCA E
Sbjct: 4031 VCADGFTSMSDRPGKRCAAE 4050
Score = 125 bits (314), Expect = 1e-26
Identities = 100/377 (26%), Positives = 171/377 (44%), Gaps = 20/377 (5%)
Frame = -1
Query: 5214 CPKANCSHFCIDRRDVGH--QCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTI 5041
C + CSH C+ H C C G+ LS + +C R+D + ++ V H + ++
Sbjct: 1704 CAFSRCSHLCLLSSQGPHFYSCVCPSGWSLSPDLLNCLRDD--QPFLITVRQHIIFGISL 1761
Query: 5040 DGHAKAT----LLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINS 4873
+ K+ ++ + NG+ +++D +YW + N I + V S
Sbjct: 1762 NPEVKSNDAMVPIAGIQNGLDVEFDDAEQYIYWVE-----NPGEIHRVKTDGTNRTVFAS 1816
Query: 4872 LPTKGID-GIAVDWLGRNIYYTDRNHDAIAVCDMRG--RFNRILLK--GTPLND--PRAI 4714
+ G +A+DW+ RN+Y T+ +I V + G R+ + L+ GT L P I
Sbjct: 1817 ISMVGPSMNLALDWISRNLYSTNPRTQSIEVLTLHGDIRYRKTLIANDGTALGVGFPIGI 1876
Query: 4713 VLDPLQALVFW----TDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYF 4546
+DP + ++W TD G A I NMDG++ + + + + +D Q+LY+
Sbjct: 1877 TVDPARGKLYWSDQGTDSGVPAKIASANMDGTSVKTLFTGN-LEHLECVTLDIEEQKLYW 1935
Query: 4545 GDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNR 4366
R I N DG+ R M+L + H + +AV + ++Y++D IERV K TG N
Sbjct: 1936 AVTGRGVIERGNVDGTDR-MILVHQLSHPWGIAVHDSFLYYTDEQYEVIERVDKATGAN- 1993
Query: 4365 KVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPAR-CDNLCIPANTPDLTTSSDNF 4189
K++++D G ++ H + S + CS C +C+P F
Sbjct: 1994 KIVLRDNVPNLRGLQVYHRRNAAESS-----NGCSNNMNACQQICLP-------VPGGLF 2041
Query: 4188 TCMCAQGFR--SEGRSC 4144
+C CA GF+ + RSC
Sbjct: 2042 SCACATGFKLNPDNRSC 2058
Score = 108 bits (269), Expect = 2e-21
Identities = 98/368 (26%), Positives = 160/368 (42%), Gaps = 16/368 (4%)
Frame = -1
Query: 5199 CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDT--IEAEILMVYGHRLKLFTIDGHAK 5026
C C+ C CA G+ L+ + + C ++ + + + + G L+L +
Sbjct: 2029 CQQICLPVPGGLFSCACATGFKLNPDNRSCSPYNSFIVVSMLSAIRGFSLEL-SDHSETM 2087
Query: 5025 ATLLSNLTNGVALDYDVKSDLVYWTD----VAHDGN----KAGITSMSNQPNTYRVINSL 4870
+ N + +D DV S +YW D VA D K +S+ N V + +
Sbjct: 2088 VPVAGQGRNALHVDVDVSSGFIYWCDFSSSVASDNAIRRIKPDGSSLMNI-----VTHGI 2142
Query: 4869 PTKGIDGIAVDWLGRNIYYTDR--NHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQ 4696
G+ GIAVDW+ N+Y+T+ + I V + + R+LLK T ++ PR IV+DP
Sbjct: 2143 GENGVRGIAVDWVAGNLYFTNAFVSETLIEVLRINTTYRRVLLKVT-VDMPRHIVVDPKN 2201
Query: 4695 ALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIAS 4516
+FW D+G I R +D +N V++ + + P LAVD +Y+ D D IA
Sbjct: 2202 RYLFWADYGQRPKIERSFLDCTNRTVLVSEGIVT-PRGLAVDRSDGYVYWVDDSLDIIAR 2260
Query: 4515 CNYDGSKRRMVLRGS-VRHIFALAVFEDYVYWSDWHNHTIERVHK-ITGTNRKVLIQDKQ 4342
+G ++ GS + + VFE+ + W D + I + K T +I+D
Sbjct: 2261 IRINGENSEVIRYGSRYPTPYGITVFENSIIWVDRNLKKIFQASKEPENTEPPTVIRDNI 2320
Query: 4341 YRPMGFKIVHPSLQSMGSLKTARHPC-SQPARCDNLCIPANTPDLTTSSDNFTCMCAQG- 4168
I +Q + +PC C +LC P L T C CA G
Sbjct: 2321 NWLRDVTIFDKQVQPRSPAEVNNNPCLENNGGCSHLCFA--LPGLHTPK----CDCAFGT 2374
Query: 4167 FRSEGRSC 4144
+S+G++C
Sbjct: 2375 LQSDGKNC 2382
Score = 103 bits (256), Expect = 7e-20
Identities = 105/385 (27%), Positives = 143/385 (36%), Gaps = 58/385 (15%)
Frame = -1
Query: 6012 CTSFEFSCESSKKCIP----LEQKCDGRRDCPDGEDEHQCETECDSKGGNATFRCTNHRC 5845
C F C S C P E +C + + C + + G ++F C+N RC
Sbjct: 2655 CEQFNGGC--SHICAPGPNGAECQCPHEGNWYLANNRKHCIVDNGERCGASSFTCSNGRC 2712
Query: 5844 IPMAWRCDGTDDCMDNAKSLGSDEVD-CAAGRTSFHVPSRCADETCVVACELTAVLCDGI 5668
I W+CD +DC D GSDE++ A T CA+ CV + CD
Sbjct: 2713 ISEEWKCDNDNDCGD-----GSDEMESVCALHTCSPTAFTCANGRCV----QYSYRCDYY 2763
Query: 5667 QDCSDGFDEKNCASLDRQCK-PNEWMCDSGQCIDSGRLCDASVDCVDGSDEWVEICSLSE 5491
DC DG DE C L R C E+MC++ +CI +C+ +C D + + C
Sbjct: 2764 NDCGDGSDEAGC--LFRDCNATTEFMCNNRRCIPREFICNGVDNCHDNNTSDEKNC---- 2817
Query: 5490 PPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQ--------CDNPQGNCSST 5335
P R C SG++ N I C+ LCDG DC DE C + + C+S
Sbjct: 2818 -PDRTCQSGYT-KCHNSNI-CIPRVYLCDGDNDCGDNSDENPTYCTTHTCSSSEFQCTSG 2874
Query: 5334 RNSCDQTWNCQRH-----AGFESCSCDDGYHLSPYDKKTC-------------------- 5230
R Q W C + A E SC D+ C
Sbjct: 2875 R-CIPQHWYCDQETDCFDASDEPASCGHSERTCLADEFKCDGGRCIPSEWICDGDNDCGD 2933
Query: 5229 ----LRSPSCPKANCS---HFCIDRRDVGHQCF-----------CAPGYILSENQKDCRR 5104
+ C NCS C++ R +C C GY ENQ +C R
Sbjct: 2934 MSDEDKRHQCQNQNCSDSEFLCVNDRPPDRRCIPQSWVCDGDVDCTDGY--DENQ-NCTR 2990
Query: 5103 NDTIEAEILMVYGHRL-KLFTIDGH 5032
E E YG + K+F D H
Sbjct: 2991 RTCSENEFTCGYGLCIPKIFRCDRH 3015
Score = 99.0 bits (245), Expect = 1e-18
Identities = 191/868 (22%), Positives = 314/868 (36%), Gaps = 65/868 (7%)
Frame = -1
Query: 2820 GVCAQKCW-MAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQ 2644
G C+ C+ + HT +C CA + ++D C +++ +F + N L + L+
Sbjct: 2351 GGCSHLCFALPGLHTPKCDCA--FGTLQSDGKNCAISTENFLIFALS-NSLRSLHLDPEN 2407
Query: 2643 VSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGN-SRVDIRSKKWSDGLIGSWGEE 2467
S N++ ++ D D T G+G S + S + +I S
Sbjct: 2408 HSPPFQTINVERTVMSLDYDSVSDRIYFTQNLASGVGQISYATLSSGIHTPTVIASG--- 2464
Query: 2466 ESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSL 2287
TA I +D++ +Y+++ Q + + A+D S RT+I ++
Sbjct: 2465 IGTADGIAFDWITRRIYYSDYLNQ-----------MINSMAEDGSNRTVIARVPKP-RAI 2512
Query: 2286 AVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFS 2107
+DP + ++W +I A L G F+ +V ++ P+ + LD+
Sbjct: 2513 VLDPCQGYLYWADWDTHAKIERATLGGN-----FRV------PIVNSSLVMPSGLTLDYE 2561
Query: 2106 NERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIY---LITRQGSIHR 1936
+ LYW+D + IE + G DR + + +T+ G YIY L T++ I+R
Sbjct: 2562 EDLLYWVDASLQRIERSTLTGVDREVIVNAAVHAFGLTL--YGQYIYWTDLYTQR--IYR 2617
Query: 1935 MHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYC---PSNTVCVP 1765
+K+ G + PR V K ++ Q N S C P+ C
Sbjct: 2618 ANKYDGSGQIAMTTNLLSQPRGINTVVKNQKQQCNNPCEQFNGGCSHICAPGPNGAECQC 2677
Query: 1764 DQDKNGILI---PKCLCGPGR-----FFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCS 1609
+ N L C+ G F S +C+ K + CGD + C+
Sbjct: 2678 PHEGNWYLANNRKHCIVDNGERCGASSFTCSNGRCISEEWKCDNDNDCGDGSDEMESVCA 2737
Query: 1608 PQKTC-----VCPPG---FYGRQCE-INECSETCWNGETCAVQEFGSTTNVVCHCPSNYT 1456
TC C G Y +C+ N+C + + C ++ +TT +C N
Sbjct: 2738 -LHTCSPTAFTCANGRCVQYSYRCDYYNDCGDGS-DEAGCLFRDCNATTEFMC----NNR 2791
Query: 1455 QSSCATNVCEGV--CGPRGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHKADAKVCY 1282
+ +C GV C + DE +C + C G+T H ++ +C
Sbjct: 2792 RCIPREFICNGVDNCHDNNT-------SDEKNCPDRT---CQSGYTKCH-----NSNICI 2836
Query: 1281 GHCFSGGACDGEGPLNLRCSCGDGLTGNRCQNCVGHECLNGGFCSYANSNRSLP-HCICP 1105
+ CDG+ CGD N C H C + F S R +P H C
Sbjct: 2837 PRVY---LCDGDN------DCGDNSDENPTY-CTTHTCSSSEF--QCTSGRCIPQHWYCD 2884
Query: 1104 SGFTGDHCEEYLCKDACPFGSKCTY-DITKPMDPITCSCEQNAAAH-----NTDCSPICQ 943
+E C DA + C + + T D C + + + DC +
Sbjct: 2885 --------QETDCFDASDEPASCGHSERTCLADEFKCDGGRCIPSEWICDGDNDCGDMSD 2936
Query: 942 KQPNWCHNGGRCLDTP-----GYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSKCTITNGT 778
+ C D+ P +C+P+ CD V C D N CT +
Sbjct: 2937 EDKRHQCQNQNCSDSEFLCVNDRPPDRRCIPQ--SWVCDGDVDCTDGYDENQNCTRRTCS 2994
Query: 777 HFECDCKPGF---KGLRCEQETKCSECSNEAKCIKKP--------------SGTVICQCP 649
E C G K RC++ C + S+E C+ + S T +C
Sbjct: 2995 ENEFTCGYGLCIPKIFRCDRHNDCGDYSDERGCLYQTCQQNQFTCQNGRCISKTFVCDED 3054
Query: 648 QGLGGEYCEKI-----TATSC--HQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCS 490
G E + +C H+ +C N G C++ N CL + KG C
Sbjct: 3055 NDCGDGSDELMHLCHTPEPTCPPHEFKCDN-GRCIEMMKLCNHLD-DCLDNSDEKG--CG 3110
Query: 489 SNACENFCLH--DGNCTLDEYFEPQCEC 412
N C + + D NCT D C C
Sbjct: 3111 INECHDPSISGCDHNCT-DTLTSFYCSC 3137
Score = 92.8 bits (229), Expect = 1e-16
Identities = 157/724 (21%), Positives = 252/724 (34%), Gaps = 40/724 (5%)
Frame = -1
Query: 2448 ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIK 2269
+ +D++ N+Y+T+S ++ I V + D + RT +V S+ V P
Sbjct: 789 LAFDWISKNLYWTDSHYKS----------ISVMRLADKTRRT-VVQYLNNPRSVVVHPFA 837
Query: 2268 RLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYW 2089
+F+T +I+ A DG + T + P + +D++ RLYW
Sbjct: 838 GYLFFTDWFRPAKIMRAWSDGSHLLPVINT-----------TLGWPNGLAIDWAASRLYW 886
Query: 2088 IDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTG-- 1918
+D IE +FDG DRR + E P + + G +++ R G+I R+ K G
Sbjct: 887 VDAYFDKIEHSTFDGLDRRRLGHIEQMTHPFGLAIFGEHLFFTDWRLGAIIRVRKADGGE 946
Query: 1917 -----KTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDK 1753
Y+ ++ IQ + + TH C S +C VP+ +
Sbjct: 947 MTVIRSGIAYILHLKSYDVNIQ-----TGSNACNQPTHPNGDC-SHFC----FPVPNFQR 996
Query: 1752 NGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCSPQKTCVCPPGFY 1573
C C G + C + QCG + P K C P +Y
Sbjct: 997 ------VCGCPYGMRLASNHLTCEGDPTNEPPTEQCGLF-------SFPCKNGRCVPNYY 1043
Query: 1572 GRQCE-INECSETCWNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVC---EGVCGPRG 1405
C+ +++C + + ++ T N C + + +C C C R
Sbjct: 1044 --LCDGVDDCHDN-------SDEQLCGTLNNTC----SSSAFTCGHGECIPAHWRCDKRN 1090
Query: 1404 SCKTVPCPKDEPHCRSYSFCEC-DKGWTGPHCRHKADAKVCYGH-CFS-GGACDGEGPLN 1234
C DE +C +++ C D +T C H C S CD +
Sbjct: 1091 DCVD---GSDEHNCPTHAPASCLDTQYT------------CDNHQCISKNWVCDTDN--- 1132
Query: 1233 LRCSCGDGLTGNRCQ----------NCVGHECLNGGFCSYANSNRSLPHCICPSGFTGDH 1084
CGDG C NC H C++ F + + C+ S G
Sbjct: 1133 ---DCGDGSDEKNCNSTETCQPSQFNCPNHRCIDLSFVCDGDKD-----CVDGSDEVGCV 1184
Query: 1083 CEEYLCKDACPFGSKCTYDITKPMDPI-TCSCEQNAAAHNTDCSPICQKQPNWCHNGGRC 907
+ C G KC +T D + CS + A T +C C G C
Sbjct: 1185 LNCTASQFKCASGDKC-IGVTNRCDGVFDCSDNSDEAGCPTRPPGMCHSDEFQCQEDGIC 1243
Query: 906 L----DTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSKCTITNGTHFECD---CKPGF 748
+ + G+P CL VP C ++F CD C
Sbjct: 1244 IPNFWECDGHP---DCLYGSDEHNACVPKTCP-------------SSYFHCDNGNCI--H 1285
Query: 747 KGLRCEQETKCSECSNEAKCIKKPSGTVICQCP----QGLGGEYCEKITATSCHQLECKN 580
+ C+++ C + S+E C +P +CP Q LG C ++ +C N
Sbjct: 1286 RXWLCDRDNDCGDMSDEKDCPTQP-----FRCPSWQWQCLGHNICVNLSVVCDGIFDCPN 1340
Query: 579 GGYCLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCLHDGNCT---LDEYFEPQCECY 409
G SP LC+ N+C +F +G CT + E F +C C
Sbjct: 1341 G----------TDESP-----------LCNGNSCSDF---NGGCTHECVQEPFGAKCLCP 1376
Query: 408 QAFI 397
F+
Sbjct: 1377 LGFL 1380
Score = 79.7 bits (195), Expect = 9e-13
Identities = 37/95 (38%), Positives = 48/95 (49%), Gaps = 7/95 (7%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADE-------SNCTCNENE 6415
D D + C + C+ F C NG CI + VC+ NDC + +DE TC +E
Sbjct: 3020 DYSDERGCLYQTCQQNQFTCQNGRCISKTFVCDEDNDCGDGSDELMHLCHTPEPTCPPHE 3079
Query: 6414 FRCQSGACIPSKARCNHMQDCNDASDEIGCPFRNC 6310
F+C +G CI CNH+ DC D SDE GC C
Sbjct: 3080 FKCDNGRCIEMMKLCNHLDDCLDNSDEKGCGINEC 3114
Score = 60.1 bits (144), Expect = 7e-07
Identities = 38/142 (26%), Positives = 62/142 (42%), Gaps = 10/142 (7%)
Frame = -1
Query: 6579 MFDDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCTCNENEFRCQS 6400
++ ++ C + C YF+C NG CI +C+R NDC + +DE +C FRC S
Sbjct: 1257 LYGSDEHNACVPKTCPSSYFHCDNGNCIHRXWLCDRDNDCGDMSDEKDCP--TQPFRCPS 1314
Query: 6399 --------GACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIH 6244
C+ C+ + DC + +DE P N ++ ++F N T +C+
Sbjct: 1315 WQWQCLGHNICVNLSVVCDGIFDCPNGTDE--SPLCNGNSCSDF------NGGCTHECVQ 1366
Query: 6243 PSW--KCDGTNDCYDGSDEKDC 6184
+ KC +D K C
Sbjct: 1367 EPFGAKCLCPLGFLLANDSKTC 1388
Score = 54.7 bits (130), Expect = 3e-05
Identities = 62/293 (21%), Positives = 107/293 (36%), Gaps = 1/293 (0%)
Frame = -1
Query: 2829 HHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLEN 2650
++ C Q C C CA G+ + D C P + + + + R + L +
Sbjct: 2024 NNMNACQQICLPVPGGLFSCACATGF-KLNPDNRSCSPYNSFIVVSMLSAIRGFSLELSD 2082
Query: 2649 SQVSVLRPVFNIKMNLIPGGIDFGYD-VFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWG 2473
+++ PV N + +D ++ +V N+ I+ S I + G
Sbjct: 2083 HSETMV-PVAGQGRNALHVDVDVSSGFIYWCDFSSSVASDNAIRRIKPDGSSLMNIVTHG 2141
Query: 2472 EEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTIN 2293
E+ I D++ N+YFT + F + I V + T R L+ +
Sbjct: 2142 IGENGVRGIAVDWVAGNLYFTNA--------FVSETLIEVLRINTTYRRVLLKVTVDMPR 2193
Query: 2292 SLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLD 2113
+ VDP R +FW P+I + LD LV I P + +D
Sbjct: 2194 HIVVDPKNRYLFWADYGQRPKIERSFLD-----------CTNRTVLVSEGIVTPRGLAVD 2242
Query: 2112 FSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITR 1954
S+ +YW+D I + +G + +R TP + V I + R
Sbjct: 2243 RSDGYVYWVDDSLDIIARIRINGENSEVIRYGSRYPTPYGITVFENSIIWVDR 2295
Score = 46.2 bits (108), Expect = 0.011
Identities = 86/356 (24%), Positives = 115/356 (32%), Gaps = 40/356 (11%)
Frame = -1
Query: 1650 QCGDYFCYNNAGCSPQKTCV-----CPPGFYGRQ-CEINECSE---TCWNGETCAVQEFG 1498
Q G + C + C P C G RQ C + CS TC NG+ C E+
Sbjct: 68 QQGYFKCQSEGQCIPSSWVCDQDQDCDDGSDERQDCSQSTCSSHQITCSNGQ-CIPSEY- 125
Query: 1497 STTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSYSFCECDKGWTGP 1318
+ V CP ++ C CE + G+C + +CD W
Sbjct: 126 -RCDHVRDCPDGADENDCQYPTCEQLTCDNGACYN-------------TSQKCD--WK-V 168
Query: 1317 HCRHKADAKVCYGHCFSGGACDGEGPLNLRC-------SCGDGLTGNRCQ--NCVGHE-C 1168
CR +D C C G G R C DG + C C G++
Sbjct: 169 DCRDSSDEINCTEICLHNEFSCGNGECIPRAYVCDHDNDCQDGSDEHACNYPTCGGYQFT 228
Query: 1167 LNGGFCSYANSNRSLPHCICPSGFTGDHCEE-----YLCKD---ACPFGSKCTYDITKPM 1012
G C Y N C D CE + C +CP +C I K
Sbjct: 229 CPSGRCIYQNWVCD-GEDDCKDNGDEDGCESGPHDVHKCSPREWSCPESGRC-ISIYKVC 286
Query: 1011 DPITCSCEQNAAAHNTD---------CSPI-CQKQPNWCHNGGRCLDTPGYPGKCKCLPR 862
D I C +NT CS + CQ Q + GG C PGY +
Sbjct: 287 DGI-LDCPGREDENNTSTGKYCSMTLCSALNCQYQCHETPYGGACFCPPGY-----IINH 340
Query: 861 FAGPRCDVPVQCDDYCTNNSKCTITNGTHFECDCKPGF---KGLRCEQETKCSECS 703
C C + + KC G H C C+ G+ +G C+ E S
Sbjct: 341 NDSRTCVEFDDCQIWGICDQKCESRPGRHL-CHCEEGYILERGQYCKANDSFGEAS 395
Score = 40.4 bits (93), Expect = 0.59
Identities = 17/40 (42%), Positives = 24/40 (59%)
Frame = -1
Query: 1170 CLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDACP 1051
C++GG C + ++ LP C CPSG+TG +CE K P
Sbjct: 4383 CMHGGNCYFDETD--LPKCKCPSGYTGKYCEMAFSKGISP 4420
Score = 38.5 bits (88), Expect = 2.2
Identities = 24/83 (28%), Positives = 36/83 (42%), Gaps = 1/83 (1%)
Frame = -1
Query: 627 CEKITATSCHQLECKNGGY-CLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCLHDGN 451
C++I + C + GGY C P S+ T C + + C C+H GN
Sbjct: 4334 CKQICSHLCL---LRPGGYSCACPQGSSFIEGSTTECDAAIELPINLPPPCR--CMHGGN 4388
Query: 450 CTLDEYFEPQCECYQAFIGDRCQ 382
C DE P+C+C + G C+
Sbjct: 4389 CYFDETDLPKCKCPSGYTGKYCE 4411
>gi|50750481|ref|XP_422014.1| PREDICTED: similar to glycoprotein
receptor gp330/megalin precursor [Gallus gallus]
Length = 4742
Score = 717 bits (1852), Expect = 0.0
Identities = 557/1844 (30%), Positives = 801/1844 (43%), Gaps = 172/1844 (9%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC---TCNEN-EFRCQ 6403
DE C+ C+P F CGNG C+P C+ NDC + +DE+ C TC+ + EF C
Sbjct: 2732 DELESVCAFHTCQPTAFTCGNGRCVPYHYRCDHYNDCGDNSDEAGCLFRTCDSHTEFTCN 2791
Query: 6402 SGACIPSKARCNHMQDC--NDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKC 6229
+G CI + CN + +C N SDE CP R C + G C +T+ CI ++ C
Sbjct: 2792 NGRCISLQYVCNGVNNCYDNGTSDERNCPERTCQS-------GFTKCQSTNICIPRTYLC 2844
Query: 6228 DGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKT----QFACLATRTCMPKHWQCDGQ 6061
DG NDC D SDE +P C + T +F C + R C+P HW CD
Sbjct: 2845 DGDNDCGDMSDE---------------SPTHCVSMTCTNNEFRCTSGR-CIPAHWYCDQG 2888
Query: 6060 PDCADGSDEK-NCD--AKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECD 5890
DCADGSDE +C+ + C+S +F C+ + CIP CDG DC D DE Q + C
Sbjct: 2889 VDCADGSDEPASCEPHVRTCSSDQFRCDDGR-CIPATWICDGDNDCGDMSDEDQRHS-CA 2946
Query: 5889 SKGGNAT-FRCTNHR-----CIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSR 5728
++ AT F C N+R CIP AW CDG DC D DE R+
Sbjct: 2947 NRSCTATEFTCANNRPPLRRCIPRAWVCDGDADCSD-----ALDEHQNCTRRSCTENEFT 3001
Query: 5727 CADETCVVACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDA 5548
C + C+ +A CD DC D DE+ C + C+ +++ C +G+CI +CD
Sbjct: 3002 CNNGLCI----RSAYRCDRRNDCGDASDERGC--IYEPCQQHQFTCQNGRCISKAYICDG 3055
Query: 5547 SVDCVDGSDEWVEICSLSEPPRRGC-PSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDE 5371
DC D SDE +CS P C P + C NG C++ ++C+ +C+ DE
Sbjct: 3056 DNDCGDESDELEHLCST---PEATCSPQHFKC--DNGN--CIEMAKVCNRLDECLDNSDE 3108
Query: 5370 QCDNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKAN--C 5197
+ + + CD + + + CSC GY L DK+TC C + C
Sbjct: 3109 KGCGINECSDPSISGCDHVCTDTQTSFY--CSCHPGYKLMS-DKRTCDDIDECNETPSVC 3165
Query: 5196 SHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATL 5017
S C + + C CAPGYI + K CR+N I ++ + L+ T DG + + +
Sbjct: 3166 SQIC-ENTAGSYICKCAPGYIREPDGKSCRQNSNISPYLIFSNRYYLRNLTADGQSYSLI 3224
Query: 5016 LSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVD 4837
L L N VALD+D +YW DV G K N N VI+ G +GIAVD
Sbjct: 3225 LQGLRNVVALDFDRVEKRLYWIDV---GRKVIERMFLNGTNKEAVISDDVPNG-EGIAVD 3280
Query: 4836 WLGRNIYYTDRNHDAIAVCDMRGRFNRILL-KGTPLND------PRAIVLDPLQALVFWT 4678
W+GR +Y+ D D I V ++ GRF + L+ + +N+ PRAIV+ P V+WT
Sbjct: 3281 WVGRKLYWVDAYKDCIYVSELDGRFQKKLVDRCVDINNTYCFQHPRAIVVHPKYGQVYWT 3340
Query: 4677 DWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGS 4498
DW A+IGR MDG + VI+ + + WPN L +D +LY+ DAH +YI + DG
Sbjct: 3341 DWADRAYIGRAGMDGKEKMVIISTK-LEWPNGLTIDYTNDKLYWADAHLNYIEYSDLDGH 3399
Query: 4497 KRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKI 4318
R V G++ H FA+ +FED +YW+DW+ T+E+ +K G+ R VL+ + +RP +
Sbjct: 3400 HRHTVYDGTLPHPFAITIFEDTIYWTDWNTRTVEKGNKYDGSGRTVLV-NTTHRPFDIHV 3458
Query: 4317 VHPSLQSMGSLKTARHPC-SQPARCDNLCIPANTPDLTTSSDNFTCMCAQGFR----SEG 4153
HP Q +PC + C +LC+ + ++C C F
Sbjct: 3459 YHPYRQPF-----VNNPCGTNNGGCSHLCL------IKAGGQGYSCECPDNFMIVQFGST 3507
Query: 4152 RSCVSECKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCG 3973
C+ C F+C T +CI WW+ CP C GQF C
Sbjct: 3508 AHCLPMCSSTQFLCADTERCIPIWWKCDGQRDCRDGSDE----PPTCPHRYCPVGQFQCN 3563
Query: 3972 RTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFC-------------------------- 3871
C LC+ DC DE+P C
Sbjct: 3564 ------DGNCTSPHFLCNTQPDCHDRSDEDPVLCGEDSTVSFLEKLGDLMSLWEMHPVAL 3617
Query: 3870 --------------ENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDE--LNCEITS 3739
N +C Q++C + K+CIP CD+E DC D SDE +C +
Sbjct: 3618 EICTSTGQPIYILSANHQCETHQWQCAN-KRCIPEAWQCDREDDCGDNSDEDTTHCASRT 3676
Query: 3738 CKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEP-DSCFGIG-EC-THEQFQC-TSG 3571
C P F C NG +CIP+ + CD +DDC + DEP C G C H QF C TS
Sbjct: 3677 CPPGQFKCDNG----RCIPESWKCDVDDDCGDNSDEPFHECMGPAYRCDNHTQFSCRTSY 3732
Query: 3570 KCIPKRRQCDGTLDCRDGSDEKGCKK-ECA----IVCDN-SCVHADDLCDGKKKCNDGSD 3409
+CIP C+G DCRD SDE+GC++ C+ CDN C+ CDG C D SD
Sbjct: 3733 RCIPLWAVCNGNDDCRDNSDEQGCEEMTCSPFGDFRCDNHRCIPLRWKCDGDNDCGDQSD 3792
Query: 3408 EDEEACVIKQLLEKE----NRKC--GGFACDGIVDCEDGSDEKGCPDLECH--------- 3274
E C ++ E E N +C + CD DCED SDE+ C CH
Sbjct: 3793 EHN--CSPRECTESEYRCDNLRCIPSRWVCDHDDDCEDNSDERDCELRTCHPGYFQCNSG 3850
Query: 3273 LASNKSLICDGTIDCSSGKDENNC---HNNG---ESNFFQCSMQT-IKEWQVCDGRWDCA 3115
+ CDG DC DE C + NG F+C I+ + CDG DC
Sbjct: 3851 HCVAERFRCDGNADCLDFSDEITCPTRYPNGTYCPPMMFECKNHVCIQPYWKCDGDNDCG 3910
Query: 3114 DGLDESPEMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDENPIHCKD---- 2947
D DE +C C++ + C+ S LC+ DC DGSDE HC++
Sbjct: 3911 DDSDEELHLCLDIACESPFRFRCENNR-CI-YSHELCNQEDDCGDGSDEKEEHCREPTPR 3968
Query: 2946 -MCKGKYRCTNGRCID---VSARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHT 2779
+++C+NG CI V +C C
Sbjct: 3969 PCTTEEFKCSNGNCIPLHYVCDNYDDCGDHFDEMGCNPGTERTCAENICEHNCTNLNEGG 4028
Query: 2778 ARCHCAPGYARTKNDENECEPLSK----------------SAEMFITNGNRLHLMSLENS 2647
C C PGY ++N+ N C+ +++ S E F +G S+ +
Sbjct: 4029 FICSCRPGYKASENNRNSCDDINECEIFGTCTQDCKNSKGSYECFCADG----FKSVGDQ 4084
Query: 2646 QVSVLRPVFNIKMNLIPGGIDF-GYDVFRTTLMYTVGIGN-SRVDIRSKKWSDGLIG--- 2482
Q N + L+P + Y++ ++ Y+ I N R+ W IG
Sbjct: 4085 QGKQCAANGNPPLLLLPDNVRIRRYNI--SSEQYSDYIDNQERIQALDYDWDPEGIGLSI 4142
Query: 2481 ------SWGEEEST---AGLITYDFMHNNVYFTESSEQNRGVLFDRQA------------ 2365
+ G + A L T+D NN T+ + N + +
Sbjct: 4143 VYFSILAQGSQFGAIKRAYLPTFDSSRNNP--TKEVDLNLRYIVNPDGLAVDWVGRHLYW 4200
Query: 2364 ------NIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGK 2203
I VAK + LI + ++AV+P L++WT P+I A +DG
Sbjct: 4201 TDAGTNRIEVAKLDGRYRKWLIFSLLDQPAAIAVNPKHGLMYWTDWGRQPKIECAWMDG- 4259
Query: 2202 PIAQPFKTGSQPHKALVERNIFEPTSMVLDF-SNERLYWIDVLKRTIETVSFDGRDRRTV 2026
Q + LV ++ PT + +D+ +N+R+YW D + IE++ DG DR V
Sbjct: 4260 ----------QQRRTLVSEDLGWPTGLSIDYLNNDRIYWSDSKENIIESMRHDGTDRTVV 4309
Query: 2025 RKFELGDTPVTMDVLGGYIYLITRQ-GSIHRMHKFTGKTNKYVQKIREVSPRI-QIRVAH 1852
E+G +P ++DV G++Y I ++ G + + KF G K K+ V+P + Q+R+ H
Sbjct: 4310 LHGEVG-SPYSLDVFEGHLYWIAKERGEVWKKDKF-GNGEKV--KVLTVNPWLTQVRIYH 4365
Query: 1851 PAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLCGPG-RFFEVSTKKCMQL 1675
++ S NPC+ D C + P C C G RF E S+ +C
Sbjct: 4366 QHRYNQS----VPNPCK-DVCSHLCLLRPGG-------YTCACPQGTRFVEGSSTECDAA 4413
Query: 1674 REKD---QEASQC-GDYFCYNNAGCSPQKTCVCPPGFYGRQCEI 1555
E A +C CY + P+ C C G+ G CEI
Sbjct: 4414 IESPPTMPPACRCMYGGTCYIDESGLPK--CKCSYGYTGDYCEI 4455
Score = 419 bits (1077), Expect = e-115
Identities = 274/784 (34%), Positives = 388/784 (48%), Gaps = 21/784 (2%)
Frame = -1
Query: 6429 CNENEFRCQSGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQC 6250
C F C +G C+P +C+ + DC+D SDE +NC +LN + CA QC
Sbjct: 1028 CGSYSFSCNNGRCVPRYYQCDGIDDCHDNSDE-----QNCGSLNNTCSSSAFTCAN-GQC 1081
Query: 6249 IHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQC 6070
I W+CD NDC+DGSDE C T G S P +T F C R C+P+ W C
Sbjct: 1082 IPSRWRCDKHNDCFDGSDELRC-----PTQGPTSCP-----ETLFTCDNNR-CIPRIWLC 1130
Query: 6069 DGQPDCADGSDEKNCD-AKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETEC 5893
D DC DGSDEKNC C +F C + CI CDG +DC DG DEH C C
Sbjct: 1131 DTDNDCGDGSDEKNCTFTGTCEPRQFQCPDHR-CIDPYYVCDGDKDCVDGADEHDCIYNC 1189
Query: 5892 DSKGGNATFRCTN-HRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRC--- 5725
F+C + +CI ++CDG DC D+ SDE DC P C
Sbjct: 1190 SG----TEFKCVSGDQCISSYYQCDGVFDCNDH-----SDETDCPT-----RPPGMCHQN 1235
Query: 5724 -----ADETCVVACELTAVLCDGIQDCSDGFDEKN-CASLDRQCKPNEWMCDSGQCIDSG 5563
+D C+ A CDG DC+DG DE + C + R C P+ + CD+G C+
Sbjct: 1236 EFQCQSDGNCIPA----NWECDGHLDCADGSDEHHRCPA--RTCPPSLFRCDNGNCVYRA 1289
Query: 5562 RLCDASVDCVDGSDEWVEICSLSEPPRRGCPSG-WSCLLTNGTIGCLQEQQLCDGRRDCM 5386
+CD DC D SDE C ++P R CPS W C G C+ ++CD DC
Sbjct: 1290 WICDGDNDCRDMSDE--RDCP-TQPFR--CPSWQWQC---PGHSICVNLSKVCDNSADCP 1341
Query: 5385 SGIDEQCDNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSC-P 5209
+G DE Q +CS C T C + C+C GY L+ D KTC C P
Sbjct: 1342 NGADESPLCNQESCSDNNAGC--THECIQGPFGAQCTCPVGYQLTN-DSKTCEDINECDP 1398
Query: 5208 KANCSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKL--FTIDG 5035
CS C + R +C+C GYIL N + C+ ++ +L+ +++ + T
Sbjct: 1399 PGFCSQHCYNERG-SFRCYCDEGYILETNGRTCKVAESGNLLLLVASRNQIVVDNITSQS 1457
Query: 5034 HAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGI 4855
H+ +L+ + N VA+D+D SD ++W+D D I S +V+
Sbjct: 1458 HSIYSLIRDGRNIVAIDFDSISDRIFWSDTTQDK----IWSAYQNGTDRKVVFDSGVTVT 1513
Query: 4854 DGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPL--QALVFW 4681
+ IAVDW+GRN+Y+TD + I V M G +L+ N PR +VLDP ++FW
Sbjct: 1514 ESIAVDWVGRNLYWTDFVLETIEVSKMDGSHRTVLISENVTN-PRGLVLDPRIDAHVMFW 1572
Query: 4680 TDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDG 4501
TDWG + I + +MDG VI+ + I WPN L++D P + LYF DA+ DYI C+Y+G
Sbjct: 1573 TDWGQNPRIEKASMDGKLRTVIISSK-IYWPNGLSIDYPNKLLYFADAYLDYIDFCDYNG 1631
Query: 4500 SKRRMVLRGS--VRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMG 4327
+ RR V+ ++H L +FED+VYWSD + + + R +K G N+ V+I + ++P+G
Sbjct: 1632 NNRRQVVASDLVLQHPHGLTIFEDFVYWSDRYTNRVIRANKWHGGNQTVMIYN-IHQPLG 1690
Query: 4326 FKIVHPSLQSMGSLKTARHPCSQPARCDNLCIPANTPDLTTSSDNFTCMCAQGF--RSEG 4153
VHP Q G A PCS +LC+ +++ L F+C C G+ +
Sbjct: 1691 LVAVHPVKQPYGINSCASSPCS------HLCLLSSSGPLF-----FSCACPSGWMLSPDN 1739
Query: 4152 RSCV 4141
R+C+
Sbjct: 1740 RNCM 1743
Score = 369 bits (947), Expect = e-100
Identities = 429/1779 (24%), Positives = 682/1779 (38%), Gaps = 139/1779 (7%)
Frame = -1
Query: 5253 SPYD--KKTCLRSPSCPKANCSHFCIDRRDVGH-QCFCAPGYILSENQKDCRRNDTIEAE 5083
SP D CL + C H C DV QC CA G + S+ ++ C TI +
Sbjct: 2339 SPLDVNNNPCLNN----NGGCFHLCFALPDVQTPQCGCAFGTLDSDGKR-C----TISTD 2389
Query: 5082 ILMVYGHRLKLFTI----DGHAKATLLSN-LTNGVALDYDVKSDLVYWTDV--AHDGNKA 4924
+++ L +I + H+ N L VALD+D ++ +Y+T + G +
Sbjct: 2390 DYLIFALENALRSIHLDPENHSPPFRAVNVLRTAVALDFDSINNRIYFTQSYPSRAGRIS 2449
Query: 4923 GITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLK 4744
I+ S V + L T DGIA DW+ +YY+D + I+ + G NR ++
Sbjct: 2450 YISIYSGIGTPIVVASDLGTP--DGIAFDWINNRVYYSDYLNQTISSMAVDGS-NRTVIA 2506
Query: 4743 GTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAP 4564
P PRA+VLDP + ++WTDW ++A I R + G+ I+ + WPN L +D
Sbjct: 2507 RVPR--PRAVVLDPCRGYMYWTDWSSNAKIERATLGGNFRTPIVSTNLV-WPNGLTLDYE 2563
Query: 4563 AQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHK 4384
Q+LY+ DA+ I C G+ R +++ ++ H FA+ +F+ ++YW+DW+ +I R +K
Sbjct: 2564 EQQLYWADANLQKIERCTLTGTNREVIVSTAL-HPFAMTLFDQHIYWTDWNTRSIYRANK 2622
Query: 4383 ITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQ-PARCDNLCIPANTPDLT 4207
G+++ V+I + RPM + S Q +PC+Q C ++C P
Sbjct: 2623 YDGSDQIVMIMNLPQRPMDIHVWAKSKQQQ-----CTNPCNQFNGGCSHICAPGPA---- 2673
Query: 4206 TSSDNFTCMCAQGFR----SEGRSCV----SECKPNDFVCTKTYKCISSWWRXXXXXXXX 4051
C C R + + C+ + C F C + CIS W+
Sbjct: 2674 ----GAECQCPSEGRWYLANNNKHCIVDNGTRCDTGFFTCLNGH-CISERWKCDNDNDCG 2728
Query: 4050 XXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFC 3871
+E VC C F CG +C+ CD DC GD+ + A C
Sbjct: 2729 DGSDE---LESVCAFHTCQPTAFTCGN------GRCVPYHYRCDHYNDC--GDNSDEAGC 2777
Query: 3870 ENFEC-TEAQFKCGDKKKCIPLTSVCDKEKDCDDG--SDELNCEITSCKPDFFACFNGTA 3700
C + +F C + + CI L VC+ +C D SDE NC +C+ F C +
Sbjct: 2778 LFRTCDSHTEFTCNNGR-CISLQYVCNGVNNCYDNGTSDERNCPERTCQSGFTKC---QS 2833
Query: 3699 ISKCIPKEFYCDGEDDCPEGQDE-PDSCFGIGECTHEQFQCTSGKCIPKRRQCDGTLDCR 3523
+ CIP+ + CDG++DC + DE P C + CT+ +F+CTSG+CIP CD +DC
Sbjct: 2834 TNICIPRTYLCDGDNDCGDMSDESPTHCVSM-TCTNNEFRCTSGRCIPAHWYCDQGVDCA 2892
Query: 3522 DGSDE--------KGCKKECAIVCDNSCVHADDLCDGKKKCNDGSDEDEE------ACVI 3385
DGSDE + C + D C+ A +CDG C D SDED+ +C
Sbjct: 2893 DGSDEPASCEPHVRTCSSDQFRCDDGRCIPATWICDGDNDCGDMSDEDQRHSCANRSCTA 2952
Query: 3384 KQLLEKENR----KC--GGFACDGIVDCEDGSDE------KGCPDLE--CH--LASNKSL 3253
+ NR +C + CDG DC D DE + C + E C+ L +
Sbjct: 2953 TEFTCANNRPPLRRCIPRAWVCDGDADCSDALDEHQNCTRRSCTENEFTCNNGLCIRSAY 3012
Query: 3252 ICDGTIDCSSGKDENNC-HNNGESNFFQCSM-QTIKEWQVCDGRWDCADGLDESPEMCAS 3079
CD DC DE C + + + F C + I + +CDG DC D DE +C++
Sbjct: 3013 RCDRRNDCGDASDERGCIYEPCQQHQFTCQNGRCISKAYICDGDNDCGDESDELEHLCST 3072
Query: 3078 RKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKGKYRCTNGRCIDV 2899
+A C + D C++++ +C+ + +C D SDE + + C D
Sbjct: 3073 PEATCSPQHFKCDNGNCIEMAK-VCNRLDECLDNSDEKGCGINECSDPSISGCDHVCTDT 3131
Query: 2898 SARXXXXXXXXXXXXXXXXGA----ECHHF-GVCAQKCWMAFNHTAR---CHCAPGYART 2743
EC+ VC+Q C +TA C CAPGY R
Sbjct: 3132 QTSFYCSCHPGYKLMSDKRTCDDIDECNETPSVCSQIC----ENTAGSYICKCAPGYIRE 3187
Query: 2742 KNDENECEPLSKSAEMFITNGNRLHLMSLENSQVSV----LRPVFNIKMNLIPGGIDFGY 2575
+ ++ + + S + +N L ++ + S+ LR V + + + + +
Sbjct: 3188 PDGKSCRQNSNISPYLIFSNRYYLRNLTADGQSYSLILQGLRNVVALDFDRVEKRL-YWI 3246
Query: 2574 DVFRTTL--MYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGLITYDFMHNNVYFTESS 2401
DV R + M+ G V +G+ W + L D + +Y +E
Sbjct: 3247 DVGRKVIERMFLNGTNKEAVISDDVPNGEGIAVDWVGRK----LYWVDAYKDCIYVSELD 3302
Query: 2400 EQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTIN---SLAVDPIKRLIFWTTSAPVPR 2230
+ + L DR +I N+T ++ V P ++WT A
Sbjct: 3303 GRFQKKLVDRCVDI---------------NNTYCFQHPRAIVVHPKYGQVYWTDWADRAY 3347
Query: 2229 ILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSF 2050
I A +DGK ++ + P + +D++N++LYW D IE
Sbjct: 3348 IGRAGMDGKE-----------KMVIISTKLEWPNGLTIDYTNDKLYWADAHLNYIEYSDL 3396
Query: 2049 DGRDRRTVRKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGKTNKYVQKIREVSPR 1873
DG R TV L P + + IY ++ + +K+ G + +
Sbjct: 3397 DGHHRHTVYDGTL-PHPFAITIFEDTIYWTDWNTRTVEKGNKYDGSGRTVL--VNTTHRP 3453
Query: 1872 IQIRVAHPAKHTVSHITHQKNPC-------------------QSDYCPSNTVCVPDQDKN 1750
I V HP + + NPC S CP N + V
Sbjct: 3454 FDIHVYHPYRQPFVN-----NPCGTNNGGCSHLCLIKAGGQGYSCECPDNFMIV-QFGST 3507
Query: 1749 GILIPKCLCGPGRFFEVSTKKCMQL----------REKDQEASQCGDYFC------YNNA 1618
+P +C +F T++C+ + R+ E C +C N+
Sbjct: 3508 AHCLP--MCSSTQFLCADTERCIPIWWKCDGQRDCRDGSDEPPTCPHRYCPVGQFQCNDG 3565
Query: 1617 GC-SPQKTCVCPPGFYGRQCE----INECSETCW---NGETCAVQEFGSTTNVVCHCPSN 1462
C SP C P + R E E S + G+ ++ E +C
Sbjct: 3566 NCTSPHFLCNTQPDCHDRSDEDPVLCGEDSTVSFLEKLGDLMSLWEMHPVALEICTSTGQ 3625
Query: 1461 YTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHKADAKVCY 1282
A + CE + C C + C C + HC + +
Sbjct: 3626 PIYILSANHQCE---THQWQCANKRCIPEAWQCDREDDCGDNSDEDTTHCASRTCPPGQF 3682
Query: 1281 GHCFSGGACDGEGPLNLRCSCGDGLTGNRCQNCVG--HECLNGGFCSYANSNRSLPHCIC 1108
C +G ++ CGD + C+G + C N S S R +P
Sbjct: 3683 -KCDNGRCIPESWKCDVDDDCGDN-SDEPFHECMGPAYRCDNHTQFSCRTSYRCIPLWAV 3740
Query: 1107 PSGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCSCEQNAAAHNTDCSPICQKQPNW 928
+G D C + + C + +TCS + N C P+ K
Sbjct: 3741 CNG--NDDCRDNSDEQGC--------------EEMTCSPFGDFRCDNHRCIPLRWK---- 3780
Query: 927 CHNGGRCLDTPGYPGKCKCLPRFAGP---RCD----VPVQCDDYCTNNSKCTITNGTHFE 769
C C D + C PR RCD +P + C ++ C N +
Sbjct: 3781 CDGDNDCGD---QSDEHNCSPRECTESEYRCDNLRCIPSRW--VCDHDDDCE-DNSDERD 3834
Query: 768 CD---CKPGF----------KGLRCEQETKCSECSNEAKC-IKKPSGTVICQCPQGLGGE 631
C+ C PG+ + RC+ C + S+E C + P+GT
Sbjct: 3835 CELRTCHPGYFQCNSGHCVAERFRCDGNADCLDFSDEITCPTRYPNGT------------ 3882
Query: 630 YCEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCLHDGN 451
YC + ECKN C++P + + C + LC ACE+
Sbjct: 3883 YCPPM------MFECKN-HVCIQPYWKCDGDN-DCGDDSDEELHLCLDIACES------- 3927
Query: 450 CTLDEYFEPQCECYQAFIGDRCQYRIHQHAVIFSDDDSG 334
F +CE +RC I+ H + +DD G
Sbjct: 3928 -----PFRFRCE------NNRC---IYSHELCNQEDDCG 3952
Score = 343 bits (879), Expect = 4e-92
Identities = 234/791 (29%), Positives = 356/791 (44%), Gaps = 27/791 (3%)
Frame = -1
Query: 6429 CNENEFRCQSGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQC 6250
C +FRC +G CIP+ RC+ +DC+D +DE GCP C N+F C T +C
Sbjct: 33 CGGGQFRCGNGRCIPADWRCDGARDCSDDTDEAGCPQPTCEG-NQF------QCQTDGEC 85
Query: 6249 IHPSWKCDGTNDCYDGSDE-KDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQ 6073
I SW CD DC DGSDE + C R+C ++ QF C + C+P ++
Sbjct: 86 IPHSWVCDDEEDCEDGSDEHQQC------------PGRTCSSQ-QFTC-SNGQCIPSAYR 131
Query: 6072 CDGQPDCADGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETEC 5893
CD DC DG+DE++C +C + SC ++ C Q+CDG+ DC D DE C C
Sbjct: 132 CDRVKDCTDGTDERDCRYPRCE--QLSC-ANGACFNASQRCDGKVDCRDTSDEANCTRGC 188
Query: 5892 DSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDC--AAGRTSFHVPSRCAD 5719
S F+C N CIP A+ CD DDC D SDE C A R +F C
Sbjct: 189 AS----TQFQCANGECIPQAFMCDHDDDCGDR-----SDENSCTYATCRGNFFT---CPS 236
Query: 5718 ETCVVACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMC-DSGQCIDSGRLCDASV 5542
C+ + +CDG DC D DE+ C S +C P EW C +SG CI G++CD +
Sbjct: 237 GRCI----HQSWICDGDDDCEDNEDERGCESSYHECYPGEWACPESGHCIPIGKVCDGAA 292
Query: 5541 DCVDGSDEW----VEICSLSEPPRRGC-------PSGWSCLLTNGTIGCLQEQQLCDGRR 5395
DC G DE C++S C PSG C +G + + C
Sbjct: 293 DCPAGEDETNITAGRHCNISHCAALSCQYRCHSSPSGGMCYCPSGYTISSNDSRTCIDFD 352
Query: 5394 DC-MSGIDEQCDNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSP 5218
DC M G+ CDQ C+ G C C +GY L
Sbjct: 353 DCKMWGV-----------------CDQL--CEDRVGHHQCHCVEGYFL------------ 381
Query: 5217 SCPKANCSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTI-EAEILMVYGHRLKLFTI 5041
E+ + CR N + A I+ G L + +
Sbjct: 382 ------------------------------EHHRHCRANTSAGVASIIFSNGRDLLIGDL 411
Query: 5040 DGHAKATLLSNLTNGVALDYDVKSDL--VYWTDVAHDGNKAGITSMSNQPNTYRVINSLP 4867
G TL+ + GVA+ D L ++WTD D + S++ + ++ + ++
Sbjct: 412 HGRNFRTLVQSQNRGVAVGVDFHFYLHRIFWTDTVQD----KVFSINIDGSDFQEVLNVS 467
Query: 4866 TKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALV 4687
+ +AVDW+ +Y + + + I + ++ G NR+ L L +PR I LDP +
Sbjct: 468 VDTPENLAVDWVNNKLYVVETSVNRIDMVNLDGT-NRVTLIAENLGNPRGIALDPTVGYL 526
Query: 4686 FWTDW---GASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIAS 4516
F++DW + R MDG+N Q +++ + + WP + +D ++RLY+ D+ DYI +
Sbjct: 527 FFSDWDSLSGDPKVERAFMDGTNRQDLIKTK-LGWPAGITLDIVSKRLYWVDSRFDYIET 585
Query: 4515 CNYDGSKRRMVLRGS--VRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQ 4342
YDG +RR + G + H + + +FE VY++DW + + +K + +N +V+ Q
Sbjct: 586 VTYDGLQRRTIAHGGSLIPHPYGITLFEHNVYFTDWTKMAVVKANKFSESNPQVIYQ-SS 644
Query: 4341 YRPMGFKIVHPSLQSMGSLKTARHPC-SQPARCDNLCIPANTPDLTTSSDNFTCMCAQGF 4165
RP G + H + Q R+PC + C+ +C+ ++ D + C C GF
Sbjct: 645 LRPYGVTVYHAARQPY-----VRNPCGNNNGGCEQICVLSHKTD--NDGLGYRCRCILGF 697
Query: 4164 --RSEGRSCVS 4138
+GR CV+
Sbjct: 698 DLHVDGRHCVA 708
Score = 327 bits (839), Expect = 2e-87
Identities = 312/1267 (24%), Positives = 505/1267 (39%), Gaps = 71/1267 (5%)
Frame = -1
Query: 5262 YHLS--PYDKKTCLRSPSCPKANCSHFCI-----DRRDVGHQCFCAPGYILSENQKDCRR 5104
YH + PY + C + C C+ D +G++C C G+ L + + C
Sbjct: 653 YHAARQPYVRNPCGNN----NGGCEQICVLSHKTDNDGLGYRCRCILGFDLHVDGRHC-- 706
Query: 5103 NDTIEAEILMVYGHRLKLFTIDGH--AKATLLSNLTNG----VALDYDVKSDLVYWTDVA 4942
+ + +++ +L + I + + ++ +T V +D+ + D ++++D +
Sbjct: 707 ---VAVQQFLLFSSQLAVRGIPFNLSTQEDVIIPVTGSPSYFVGIDFWAQDDTIFFSDTS 763
Query: 4941 HDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRF 4762
D I + ++ + + ++ +A DW+ +N+Y+TD + +I+V + +
Sbjct: 764 RDM----IYKQKTDGSGREILTANRVESVEDLAFDWISKNLYWTDPRYRSISVMRLADKS 819
Query: 4761 NRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNA 4582
R +++ LN+PR+IV+ P+ +FWTDW A I R DGS+ I+ + T+ WPN
Sbjct: 820 RRAIVQN--LNNPRSIVVHPVIGYIFWTDWFRPAKIMRAWSDGSHGLPIV-NTTLGWPNG 876
Query: 4581 LAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLR-GSVRHIFALAVFEDYVYWSDWHNH 4405
LA+D + RLY+ DA D I +DG RR + R + H F L +F Y Y++DW
Sbjct: 877 LAIDWSSLRLYWVDAFFDKIEHSTFDGLDRRTLERVAQMTHPFGLTIFGGYAYFTDWRLG 936
Query: 4404 TIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPAR----CDNL 4237
I RV K G ++ R I+H S + + C++ C +
Sbjct: 937 AIVRVRKSDGGEMTII------RRGISNIMHVKAYDAHS-QIGSNYCNRGTNPNGDCSHF 989
Query: 4236 CIPANTPDLTTSSDNF--TCMCAQGFR--SEGRSCVSECKPNDFVCTKTYKCISSWWRXX 4069
C P NF C C G + S +CV +
Sbjct: 990 CFPV---------PNFQRVCGCPYGMKLGSNQLTCVEDPSNEP----------------- 1023
Query: 4068 XXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDD 3889
P C + F C +C+ CDG+ DC D
Sbjct: 1024 -------------------PTLQCGSYSFSCN------NGRCVPRYYQCDGIDDCHDNSD 1058
Query: 3888 EEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEI---TSCKPDFFA 3718
E+ N C+ + F C + +CIP CDK DC DGSDEL C TSC F
Sbjct: 1059 EQNCGSLNNTCSSSAFTCAN-GQCIPSRWRCDKHNDCFDGSDELRCPTQGPTSCPETLFT 1117
Query: 3717 CFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQCDG 3538
C N ++CIP+ + CD ++DC +G DE +C G C QFQC +CI CDG
Sbjct: 1118 CDN----NRCIPRIWLCDTDNDCGDGSDE-KNCTFTGTCEPRQFQCPDHRCIDPYYVCDG 1172
Query: 3537 TLDCRDGSDEKGCKKECA-----IVCDNSCVHADDLCDGKKKCNDGSDEDEEACVIKQLL 3373
DC DG+DE C C+ V + C+ + CDG CND SDE + +
Sbjct: 1173 DKDCVDGADEHDCIYNCSGTEFKCVSGDQCISSYYQCDGVFDCNDHSDETDCPTRPPGMC 1232
Query: 3372 EKENRKC--------GGFACDGIVDCEDGSDE-KGCPDLECHLA---------SNKSLIC 3247
+ +C + CDG +DC DGSDE CP C + ++ IC
Sbjct: 1233 HQNEFQCQSDGNCIPANWECDGHLDCADGSDEHHRCPARTCPPSLFRCDNGNCVYRAWIC 1292
Query: 3246 DGTIDCSSGKDENNCHNNG---ESNFFQCSMQTI--KEWQVCDGRWDCADGLDESP---- 3094
DG DC DE +C S +QC +I +VCD DC +G DESP
Sbjct: 1293 DGDNDCRDMSDERDCPTQPFRCPSWQWQCPGHSICVNLSKVCDNSADCPNGADESPLCNQ 1352
Query: 3093 EMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKGKYRCTNG 2914
E C+ A C +C G P + C Y+ TN
Sbjct: 1353 ESCSDNNAGC----------------------THECIQG----PFGAQCTCPVGYQLTND 1386
Query: 2913 --RCIDVSARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTK 2740
C D++ EC G C+Q C+ + RC+C GY
Sbjct: 1387 SKTCEDIN--------------------ECDPPGFCSQHCYNE-RGSFRCYCDEGYILET 1425
Query: 2739 NDENECEPLSKSAEMFITNGNRL---HLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDV 2569
N S + + + + N++ ++ S +S S++R NI + +D
Sbjct: 1426 NGRTCKVAESGNLLLLVASRNQIVVDNITSQSHSIYSLIRDGRNI--------VAIDFDS 1477
Query: 2568 FRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGL-----ITYDFMHNNVYFTES 2404
+ ++ + K WS G+ + +G+ I D++ N+Y+T+
Sbjct: 1478 ISDRIFWS-------DTTQDKIWSAYQNGTDRKVVFDSGVTVTESIAVDWVGRNLYWTDF 1530
Query: 2403 SEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDP--IKRLIFWTTSAPVPR 2230
+ I V+K + LI + L +DP ++FWT PR
Sbjct: 1531 VLE----------TIEVSKMDGSHRTVLISENVTNPRGLVLDPRIDAHVMFWTDWGQNPR 1580
Query: 2229 ILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSF 2050
I A++DGK ++ I+ P + +D+ N+ LY+ D I+ +
Sbjct: 1581 IEKASMDGK-----------LRTVIISSKIYWPNGLSIDYPNKLLYFADAYLDYIDFCDY 1629
Query: 2049 DGRDRRTVRKFELG-DTPVTMDVLGGYIYLITR-QGSIHRMHKFTGKTNKYVQKIREVSP 1876
+G +RR V +L P + + ++Y R + R +K+ G + I +
Sbjct: 1630 NGNNRRQVVASDLVLQHPHGLTIFEDFVYWSDRYTNRVIRANKWHGGNQTVM--IYNIHQ 1687
Query: 1875 RIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLCGPGRFFEVS 1696
+ + HP K + N C S P + +C+ +G L C C G
Sbjct: 1688 PLGLVAVHPVKQ-----PYGINSCASS--PCSHLCL--LSSSGPLFFSCACPSGWMLSPD 1738
Query: 1695 TKKCMQL 1675
+ CM++
Sbjct: 1739 NRNCMRV 1745
Score = 212 bits (540), Expect = 9e-53
Identities = 209/811 (25%), Positives = 318/811 (38%), Gaps = 34/811 (4%)
Frame = -1
Query: 3999 CIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKK 3820
C GQF CG +C+ A CDG +DCS DD + A C C QF+C +
Sbjct: 33 CGGGQFRCGN------GRCIPADWRCDGARDCS--DDTDEAGCPQPTCEGNQFQCQTDGE 84
Query: 3819 CIPLTSVCDKEKDCDDGSDE-LNCEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPE 3643
CIP + VCD E+DC+DGSDE C +C F C NG +CIP + CD DC +
Sbjct: 85 CIPHSWVCDDEEDCEDGSDEHQQCPGRTCSSQQFTCSNG----QCIPSAYRCDRVKDCTD 140
Query: 3642 GQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQCDGTLDCRDGSDEKGCKKECA---IVCD 3472
G DE D + C EQ C +G C ++CDG +DCRD SDE C + CA C
Sbjct: 141 GTDERDCRY--PRC--EQLSCANGACFNASQRCDGKVDCRDTSDEANCTRGCASTQFQCA 196
Query: 3471 N-SCVHADDLCDGKKKCNDGSDEDE--EACVIKQLLEKENRKC--GGFACDGIVDCEDGS 3307
N C+ +CD C D SDE+ A + +C + CDG DCED
Sbjct: 197 NGECIPQAFMCDHDDDCGDRSDENSCTYATCRGNFFTCPSGRCIHQSWICDGDDDCEDNE 256
Query: 3306 DEKGCPDL--ECH---LASNKS-------LICDGTIDCSSGKDENNCHNNGESNFFQCSM 3163
DE+GC EC+ A +S +CDG DC +G+DE N N C+
Sbjct: 257 DERGCESSYHECYPGEWACPESGHCIPIGKVCDGAADCPAGEDETNITAGRHCNISHCAA 316
Query: 3162 QTIKEWQVCDGRWDCADGLDESPEMCASRKARCFRIGY---CDDKKQCLDVSTALCDGIR 2992
+ ++ C C S GY +D + C+D G+
Sbjct: 317 LSC--------QYRCHSSPSGGMCYCPS--------GYTISSNDSRTCIDFDDCKMWGV- 359
Query: 2991 DCFDGSDENPIHCKDMCKGKYRCTNGRCIDVSARXXXXXXXXXXXXXXXXGAECHHFGVC 2812
C +C+ + HH C
Sbjct: 360 ------------CDQLCEDRVG--------------------------------HHQCHC 375
Query: 2811 AQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQVSVL 2632
+ ++ + R + + G A + +NG L + L
Sbjct: 376 VEGYFLEHHRHCRANTSAGVA----------------SIIFSNGRDLLIGDLHGRN---F 416
Query: 2631 RPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAG 2452
R + + + G+DF + + R TV ++I + + L S E+ A
Sbjct: 417 RTLVQSQNRGVAVGVDFHFYLHRIFWTDTVQDKVFSINIDGSDFQEVLNVSVDTPENLA- 475
Query: 2451 LITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPI 2272
D+++N +Y E+S I + T+ TLI + G +A+DP
Sbjct: 476 ---VDWVNNKLYVVETSVN----------RIDMVNLDGTNRVTLIAENLGNPRGIALDPT 522
Query: 2271 KRLIF---WTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNE 2101
+F W + + P++ A +DG T Q L++ + P + LD ++
Sbjct: 523 VGYLFFSDWDSLSGDPKVERAFMDG--------TNRQD---LIKTKLGWPAGITLDIVSK 571
Query: 2100 RLYWIDVLKRTIETVSFDGRDRRTV-RKFELGDTPVTMDVLGGYIYLI--TRQGSIHRMH 1930
RLYW+D IETV++DG RRT+ L P + + +Y T+ +
Sbjct: 572 RLYWVDSRFDYIETVTYDGLQRRTIAHGGSLIPHPYGITLFEHNVYFTDWTKMAVV---- 627
Query: 1929 KFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQ---KNPCQSDYCPSNTVCV-PD 1762
K NK+ + +V + +R P TV H Q +NPC ++ +CV
Sbjct: 628 ----KANKFSESNPQVIYQSSLR---PYGVTVYHAARQPYVRNPCGNNNGGCEQICVLSH 680
Query: 1761 QDKNGILIPKCLCGPGRFFEVSTKKCMQLRE 1669
+ N L +C C G V + C+ +++
Sbjct: 681 KTDNDGLGYRCRCILGFDLHVDGRHCVAVQQ 711
Score = 173 bits (438), Expect = 6e-41
Identities = 124/361 (34%), Positives = 158/361 (43%), Gaps = 12/361 (3%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCG-NGLCIPEQKVCNRINDCANFADE-SNC---TCNENEFR 6409
DD D C C F C +G CIP VC+ DC + +DE C TC+ +F
Sbjct: 60 DDTDEAGCPQPTCEGNQFQCQTDGECIPHSWVCDDEEDCEDGSDEHQQCPGRTCSSQQFT 119
Query: 6408 CQSGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKC 6229
C +G CIPS RC+ ++DC D +DE C + C L +CA C + S +C
Sbjct: 120 CSNGQCIPSAYRCDRVKDCTDGTDERDCRYPRCEQL---------SCA-NGACFNASQRC 169
Query: 6228 DGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCA 6049
DG DC D SDE +C R C A TQF C A C+P+ + CD DC
Sbjct: 170 DGKVDCRDTSDEANC-------------TRGC-ASTQFQC-ANGECIPQAFMCDHDDDCG 214
Query: 6048 DGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNAT 5869
D SDE +C C F+C S +CI CDG DC D EDE CE+
Sbjct: 215 DRSDENSCTYATCRGNFFTCPSG-RCIHQSWICDGDDDCEDNEDERGCESSYHECYPGEW 273
Query: 5868 FRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVP-SRCADETCVVACEL 5692
+ CIP+ CDG DC G DE + AGR H S CA +C C
Sbjct: 274 ACPESGHCIPIGKVCDGAADC-----PAGEDETNITAGR---HCNISHCAALSCQYRCHS 325
Query: 5691 TAVLCDGIQDCSDGF-----DEKNCASLDRQCKPNEW-MCDSGQCIDSGRLCDASVDCVD 5530
+ G+ C G+ D + C D CK W +CD C D R+ CV+
Sbjct: 326 SP--SGGMCYCPSGYTISSNDSRTCIDFD-DCK--MWGVCDQ-LCED--RVGHHQCHCVE 377
Query: 5529 G 5527
G
Sbjct: 378 G 378
Score = 151 bits (382), Expect = 2e-34
Identities = 105/304 (34%), Positives = 135/304 (43%), Gaps = 31/304 (10%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC---TCNENEFRCQ 6403
D D CS R C + C N CIP + VC+ +DC + +DE +C TC+ F+C
Sbjct: 3789 DQSDEHNCSPRECTESEYRCDNLRCIPSRWVCDHDDDCEDNSDERDCELRTCHPGYFQCN 3848
Query: 6402 SGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDG 6223
SG C+ + RC+ DC D SDEI CP R + + + C CI P WKCDG
Sbjct: 3849 SGHCVAERFRCDGNADCLDFSDEITCPTRYPN--GTYCPPMMFEC-KNHVCIQPYWKCDG 3905
Query: 6222 TNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADG 6043
NDC D SDE+ + +C++ +F C R C+ H C+ + DC DG
Sbjct: 3906 DNDCGDDSDEE----------LHLCLDIACESPFRFRCENNR-CIYSHELCNQEDDCGDG 3954
Query: 6042 SDEK--NC---DAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCE--TECDSK 5884
SDEK +C + CT+ EF C S+ CIPL CD DC D DE C TE
Sbjct: 3955 SDEKEEHCREPTPRPCTTEEFKC-SNGNCIPLHYVCDNYDDCGDHFDEMGCNPGTERTCA 4013
Query: 5883 GGNATFRCTNHR-------CIP-------MAWRCDGTDDC-------MDNAKSLGSDEVD 5767
CTN C P CD ++C D S GS E
Sbjct: 4014 ENICEHNCTNLNEGGFICSCRPGYKASENNRNSCDDINECEIFGTCTQDCKNSKGSYECF 4073
Query: 5766 CAAG 5755
CA G
Sbjct: 4074 CADG 4077
Score = 128 bits (322), Expect = 2e-27
Identities = 100/334 (29%), Positives = 129/334 (37%), Gaps = 22/334 (6%)
Frame = -1
Query: 4134 CKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNA 3955
C+ N F C +CI W CP C + QF C +
Sbjct: 72 CEGNQFQCQTDGECIPHSWVCDDEEDCEDGSDE----HQQCPGRTCSSQQFTC------S 121
Query: 3954 TAQCLYASKLCDGVKDCSGGDDEEPA---FCENFECTEAQFKCGDKKKCIPLTSVCDKEK 3784
QC+ ++ CD VKDC+ G DE CE C C + CD +
Sbjct: 122 NGQCIPSAYRCDRVKDCTDGTDERDCRYPRCEQLSCANG--------ACFNASQRCDGKV 173
Query: 3783 DCDDGSDELNCEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGE 3604
DC D SDE NC C F C NG +CIP+ F CD +DDC + DE +SC
Sbjct: 174 DCRDTSDEANC-TRGCASTQFQCANG----ECIPQAFMCDHDDDCGDRSDE-NSC-TYAT 226
Query: 3603 CTHEQFQCTSGKCIPKRRQCDGTLDCRDGSDEKGCKK---EC---AIVCDNS--CVHADD 3448
C F C SG+CI + CDG DC D DE+GC+ EC C S C+
Sbjct: 227 CRGNFFTCPSGRCIHQSWICDGDDDCEDNEDERGCESSYHECYPGEWACPESGHCIPIGK 286
Query: 3447 LCDGKKKCNDGSDEDE----EACVIKQLLEKE-NRKCGGFACDGIVDCEDG-----SDEK 3298
+CDG C G DE C I +C G+ C G +D +
Sbjct: 287 VCDGAADCPAGEDETNITAGRHCNISHCAALSCQYRCHSSPSGGMCYCPSGYTISSNDSR 346
Query: 3297 GCPDL-ECHLASNKSLICDGTIDCSSGKDENNCH 3199
C D +C + +CD C + CH
Sbjct: 347 TCIDFDDCKMWG----VCDQL--CEDRVGHHQCH 374
Score = 126 bits (316), Expect = 8e-27
Identities = 83/265 (31%), Positives = 112/265 (41%), Gaps = 25/265 (9%)
Frame = -1
Query: 6579 MFDDEDTKYCSTRVCRPGYFNCGNG-----LCIPEQKVCNRINDCANFADE-SNCT---C 6427
M D++ C+ R C F C N CIP VC+ DC++ DE NCT C
Sbjct: 2936 MSDEDQRHSCANRSCTATEFTCANNRPPLRRCIPRAWVCDGDADCSDALDEHQNCTRRSC 2995
Query: 6426 NENEFRCQSGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCI 6247
ENEF C +G CI S RC+ DC DASDE GC + C ++F +CI
Sbjct: 2996 TENEFTCNNGLCIRSAYRCDRRNDCGDASDERGCIYEPCQQ-HQF-------TCQNGRCI 3047
Query: 6246 HPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCD 6067
++ CDG NDC D SDE + S P + + F C C+ C+
Sbjct: 3048 SKAYICDGDNDCGDESDELEHL---------CSTPEATCSPQHFKC-DNGNCIEMAKVCN 3097
Query: 6066 GQPDCADGSDEKNCDAKKC----------------TSFEFSCESSKKCIPLEQKCDGRRD 5935
+C D SDEK C +C TSF SC K + ++ CD +
Sbjct: 3098 RLDECLDNSDEKGCGINECSDPSISGCDHVCTDTQTSFYCSCHPGYKLMSDKRTCDDIDE 3157
Query: 5934 CPDGEDEHQCETECDSKGGNATFRC 5860
C E C C++ G+ +C
Sbjct: 3158 C--NETPSVCSQICENTAGSYICKC 3180
Score = 123 bits (309), Expect = 5e-26
Identities = 105/388 (27%), Positives = 171/388 (44%), Gaps = 19/388 (4%)
Frame = -1
Query: 5250 PYDKKTCLRSPSCPKANCSHFCI--DRRDVGHQCFCAPGYILSENQKDCRRND---TIEA 5086
PY +C SP CSH C+ + C C G++LS + ++C R + I
Sbjct: 1700 PYGINSCASSP------CSHLCLLSSSGPLFFSCACPSGWMLSPDNRNCMRVEHPFLIAV 1753
Query: 5085 EILMVYGHRLKLFTIDGHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMS 4906
++YG L A + + + NGV +D+D ++YW + N I +
Sbjct: 1754 RDNIIYGISLNPEEKTNDAMVPI-AGVQNGVDVDFDDSEQMIYWVE-----NPGEIHRVR 1807
Query: 4905 NQPNTYRVINSLPTKGID-GIAVDWLGRNIYYTDRNHDAIAVCDMRG----RFNRILLKG 4741
+ + V G G+A+DW+ N+YY++ +I V + G R I G
Sbjct: 1808 SDGSNRTVFAPAAVIGAPIGLALDWISANLYYSNPGTQSIEVLKLHGEVMYRKTLITNDG 1867
Query: 4740 TPLN--DPRAIVLDPLQALVFWTDWGAS----AHIGRMNMDGSNEQVILQDRTIRWPNAL 4579
T L P + +DP + ++WTD G A + NMDGS Q + + +
Sbjct: 1868 TSLGAGTPIGLTVDPARGKLYWTDQGTDSGVPAKVASANMDGSGIQTLFTGN-LDHVEFI 1926
Query: 4578 AVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTI 4399
+D Q+LY+ I N DG+ R + L + H + +AV++ ++Y++D I
Sbjct: 1927 TIDIKEQKLYWAVTSTGVIEKGNVDGTNR-VTLVIHLSHPWGIAVYDTFLYYTDRDYEVI 1985
Query: 4398 ERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQP-ARCDNLCIPAN 4222
ERV K TG N KV+++D R ++ + S GS + CS C +LC+P
Sbjct: 1986 ERVDKFTGAN-KVVLRDNVPRLKCLRVYYRD-NSAGS----SNGCSNNIGVCQHLCLP-- 2037
Query: 4221 TPDLTTSSDNFTCMCAQGFR--SEGRSC 4144
F+C CA GF+ + R+C
Sbjct: 2038 -----VPGGLFSCACATGFQLNPDNRTC 2060
Score = 115 bits (288), Expect = 1e-23
Identities = 97/362 (26%), Positives = 160/362 (43%), Gaps = 10/362 (2%)
Frame = -1
Query: 5199 CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTID-GHAKA 5023
C H C+ C CA G+ L+ + + C ++ ++ L T D A
Sbjct: 2031 CQHLCLPVPGGLFSCACATGFQLNPDNRTCSPYNSFVIVSMLSAIKGFSLETSDHSEAMV 2090
Query: 5022 TLLSNLTNGVALDYDVKSDLVYWTDVAHD-GNKAGITSMSNQPNTYR--VINSLPTKGID 4852
L N + +D + S +YW D + ++ I + + +R V N + GI
Sbjct: 2091 PLAGRGRNVLHVDVHMPSGFIYWCDYSSTVSSQNAIRKIKPDGSYFRNVVTNGIGRNGIR 2150
Query: 4851 GIAVDWLGRNIYYTDR--NHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWT 4678
GIA+DW+ N+Y+T+ I V + + R+LLK T ++ PR IV+DP +FW
Sbjct: 2151 GIAIDWVAGNLYFTNAFLTETFIEVLRLNTTYRRVLLK-TTIDMPRHIVVDPKNRYLFWA 2209
Query: 4677 DWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGS 4498
D+G + I R +D +N V++ + + P LA+D +Y+ D D IA DG
Sbjct: 2210 DYGQNPKIERSFLDCTNRTVLVSEGIVT-PRGLAIDHSNGYVYWVDDSLDMIARIQPDGG 2268
Query: 4497 KRRMVLRGS-VRHIFALAVFEDYVYWSDWHNHTIERVHKITG-TNRKVLIQDKQYRPMGF 4324
+V GS + + +F + + W D + + + K G T++ +I+D
Sbjct: 2269 DVEIVRYGSRYPTPYGITIFGNSMIWVDRNLKKVFQASKEPGNTDQPTVIRDNINWLRDV 2328
Query: 4323 KIVHPSLQSMGSLKTARHPC-SQPARCDNLCIPANTPDLTTSSDNFTCMCAQG-FRSEGR 4150
I + QS L +PC + C +LC PD+ T C CA G S+G+
Sbjct: 2329 TIYNSHFQSRSPLDVNNNPCLNNNGGCFHLCFA--LPDVQTPQ----CGCAFGTLDSDGK 2382
Query: 4149 SC 4144
C
Sbjct: 2383 RC 2384
Score = 115 bits (287), Expect = 2e-23
Identities = 185/780 (23%), Positives = 277/780 (34%), Gaps = 63/780 (8%)
Frame = -1
Query: 2547 TVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGLI------TYDFMHNNVYFTESSEQNRG 2386
T+ ++ D+ K+ +DG G E TA + +D++ N+Y+T+
Sbjct: 756 TIFFSDTSRDMIYKQKTDGS----GREILTANRVESVEDLAFDWISKNLYWTDP------ 805
Query: 2385 VLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDG 2206
R +I V + D S R ++ N S+ V P+ IFWT +I+ A DG
Sbjct: 806 ----RYRSISVMRLADKSRRAIVQNLNNP-RSIVVHPVIGYIFWTDWFRPAKIMRAWSDG 860
Query: 2205 KPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTV 2026
+V + P + +D+S+ RLYW+D IE +FDG DRRT+
Sbjct: 861 SH-----------GLPIVNTTLGWPNGLAIDWSSLRLYWVDAFFDKIEHSTFDGLDRRTL 909
Query: 2025 RKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHP 1849
+ P + + GGY Y R G+I R+ K G +++
Sbjct: 910 ERVAQMTHPFGLTIFGGYAYFTDWRLGAIVRVRKSDGGEMTIIRR--------------- 954
Query: 1848 AKHTVSHITHQK-----NPCQSDYCPSNTVCVPDQDKNGILIP------KCLCGPGRFFE 1702
+S+I H K + S+YC T P+ D + P C C G
Sbjct: 955 ---GISNIMHVKAYDAHSQIGSNYCNRGT--NPNGDCSHFCFPVPNFQRVCGCPYGMKLG 1009
Query: 1701 VSTKKCMQLREKDQEASQCGDY-FCYNNAGCSPQKTCVCPPGFYGRQCE-INECSETCWN 1528
+ C++ + QCG Y F NN C P+ +Y QC+ I++C + N
Sbjct: 1010 SNQLTCVEDPSNEPPTLQCGSYSFSCNNGRCVPR--------YY--QCDGIDDCHD---N 1056
Query: 1527 GETCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGP-RGSC-KTVPC--PKDEPHCR 1360
+ Q GS N T SS A G C P R C K C DE C
Sbjct: 1057 SDE---QNCGSLNN---------TCSSSAFTCANGQCIPSRWRCDKHNDCFDGSDELRCP 1104
Query: 1359 SYSFCECDKGWTGPHCRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQ--- 1189
+ C P D C + CD + CGDG C
Sbjct: 1105 TQGPTSC------PETLFTCDNNRCIPRIW---LCDTDN------DCGDGSDEKNCTFTG 1149
Query: 1188 -------NCVGHECLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDA---CPFGSK 1039
C H C++ + + + C G +H Y C C G +
Sbjct: 1150 TCEPRQFQCPDHRCIDPYYVCDGDKD-------CVDG-ADEHDCIYNCSGTEFKCVSGDQ 1201
Query: 1038 CTYDITKPMDPITCSCEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRF 859
C + C N + TDC + P CH + G C+P
Sbjct: 1202 CISSYYQCDGVFDC----NDHSDETDCP---TRPPGMCHQNEFQCQSDG-----NCIP-- 1247
Query: 858 AGPRCDVPVQCDDYCTNNSKCTITN--GTHFECD---CKPGFKGLRCEQETKCSECSNEA 694
A CD + C D + +C + F CD C ++ C+ + C + S+E
Sbjct: 1248 ANWECDGHLDCADGSDEHHRCPARTCPPSLFRCDNGNCV--YRAWICDGDNDCRDMSDER 1305
Query: 693 KCIKKP--SGTVICQCPQGLGGEYCEKITATSCHQLECKNGG----YCLKPDPSANRTSP 532
C +P + QCP G C ++ + +C NG C + S N
Sbjct: 1306 DCPTQPFRCPSWQWQCP---GHSICVNLSKVCDNSADCPNGADESPLCNQESCSDNNAGC 1362
Query: 531 TCLCSPGFKGLLCS----------SNACE--NFCLHDGNCTLDEYFEP---QCECYQAFI 397
T C G G C+ S CE N C G C+ Y E +C C + +I
Sbjct: 1363 THECIQGPFGAQCTCPVGYQLTNDSKTCEDINECDPPGFCSQHCYNERGSFRCYCDEGYI 1422
Score = 110 bits (274), Expect = 6e-22
Identities = 89/301 (29%), Positives = 125/301 (40%), Gaps = 29/301 (9%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCT--------CNEN 6418
D+ D + C R C PGYF C +G C+ E+ C+ DC +F+DE C C
Sbjct: 3828 DNSDERDCELRTCHPGYFQCNSGHCVAERFRCDGNADCLDFSDEITCPTRYPNGTYCPPM 3887
Query: 6417 EFRCQSGACIPSKARCNHMQDCNDASDE-------IGC--PFRNCSALNEFGMTGLINCA 6265
F C++ CI +C+ DC D SDE I C PFR C
Sbjct: 3888 MFECKNHVCIQPYWKCDGDNDCGDDSDEELHLCLDIACESPFR-------------FRC- 3933
Query: 6264 TTSQCIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMP 6085
++CI+ C+ +DC DGSDEK+ PR C + +F C + C+P
Sbjct: 3934 ENNRCIYSHELCNQEDDCGDGSDEKEEHCR-------EPTPRPCTTE-EFKC-SNGNCIP 3984
Query: 6084 KHWQCDGQPDCADGSDEKNCD-AKKCTSFEFSCESS----------KKCIPLEQKCDGRR 5938
H+ CD DC D DE C+ + T E CE + C P + + R
Sbjct: 3985 LHYVCDNYDDCGDHFDEMGCNPGTERTCAENICEHNCTNLNEGGFICSCRPGYKASENNR 4044
Query: 5937 DCPDGEDEHQCETECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDE-VDCA 5761
+ D D ++CE G T C N + ++ C C D KS+G + CA
Sbjct: 4045 NSCD--DINECEI-----FGTCTQDCKNSK---GSYEC----FCADGFKSVGDQQGKQCA 4090
Query: 5760 A 5758
A
Sbjct: 4091 A 4091
Score = 87.8 bits (216), Expect = 3e-15
Identities = 71/239 (29%), Positives = 95/239 (39%), Gaps = 3/239 (1%)
Frame = -1
Query: 5889 SKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETC 5710
++G N C+ H C P+ C K LGS+++ C ++ +C +
Sbjct: 977 NRGTNPNGDCS-HFCFPVP-NFQRVCGCPYGMK-LGSNQLTCVEDPSNEPPTLQCGSYSF 1033
Query: 5709 VV---ACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASVD 5539
C CDGI DC D DE+NC SL+ C + + C +GQCI S CD D
Sbjct: 1034 SCNNGRCVPRYYQCDGIDDCHDNSDEQNCGSLNNTCSSSAFTCANGQCIPSRWRCDKHND 1093
Query: 5538 CVDGSDEWVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDN 5359
C DGSDE P +G S L T C+ LCD DC G DE+
Sbjct: 1094 CFDGSDE-------LRCPTQGPTSCPETLFTCDNNRCIPRIWLCDTDNDCGDGSDEK--- 1143
Query: 5358 PQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKANCSHFCI 5182
NC+ T + + C H C D Y++ DK C H CI
Sbjct: 1144 ---NCTFTGTCEPRQFQCPDH------RCIDPYYVCDGDK-------DCVDGADEHDCI 1186
Score = 70.5 bits (171), Expect = 5e-10
Identities = 66/270 (24%), Positives = 91/270 (33%), Gaps = 23/270 (8%)
Frame = -1
Query: 4284 KTARHP-CSQPARCDNLCIPANTP-----DLTTSSDNFTCMCAQGFRSEGRSCVS-ECKP 4126
+ R+P C Q + + C A+ D +SD C +G S C + EC P
Sbjct: 145 RDCRYPRCEQLSCANGACFNASQRCDGKVDCRDTSDEANC--TRGCASTQFQCANGECIP 202
Query: 4125 NDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQ 3946
F+C C E C C F C + +
Sbjct: 203 QAFMCDHDDDC------------------GDRSDENSCTYATCRGNFFTC------PSGR 238
Query: 3945 CLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGS 3766
C++ S +CDG DC +DE EC ++ C + CIP+ VCD DC G
Sbjct: 239 CIHQSWICDGDDDCEDNEDERGCESSYHECYPGEWACPESGHCIPIGKVCDGAADCPAGE 298
Query: 3765 DELN------CEITSCK--PDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGI 3610
DE N C I+ C + C + + C Y +D D D C
Sbjct: 299 DETNITAGRHCNISHCAALSCQYRCHSSPSGGMCYCPSGYTISSNDSRTCIDF-DDCKMW 357
Query: 3609 GECT--------HEQFQCTSGKCIPKRRQC 3544
G C H Q C G + R C
Sbjct: 358 GVCDQLCEDRVGHHQCHCVEGYFLEHHRHC 387
Score = 63.2 bits (152), Expect = 8e-08
Identities = 39/126 (30%), Positives = 53/126 (41%), Gaps = 1/126 (0%)
Frame = -1
Query: 5679 CDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASVDCVDGSDEWVEICS 5500
CD DC DG DE C+P + C +G+C+ CD DC D SDE C
Sbjct: 2721 CDNDNDCGDGSDELESVCAFHTCQPTAFTCGNGRCVPYHYRCDHYNDCGDNSDE--AGCL 2778
Query: 5499 LSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCM-SGIDEQCDNPQGNCSSTRNSC 5323
R C S NG C+ Q +C+G +C +G ++ + P+ C S C
Sbjct: 2779 F-----RTCDSHTEFTCNNGR--CISLQYVCNGVNNCYDNGTSDERNCPERTCQSGFTKC 2831
Query: 5322 DQTWNC 5305
T C
Sbjct: 2832 QSTNIC 2837
Score = 63.2 bits (152), Expect = 8e-08
Identities = 88/400 (22%), Positives = 147/400 (36%), Gaps = 18/400 (4%)
Frame = -1
Query: 2829 HHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLEN 2650
++ GVC C C CA G+ + D C P + + ++ + + SLE
Sbjct: 2026 NNIGVCQHLCLPVPGGLFSCACATGF-QLNPDNRTCSPYNSF--VIVSMLSAIKGFSLET 2082
Query: 2649 SQVSVL--------RPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSD 2494
S S R V ++ +++ P G + D T +S+ IR K
Sbjct: 2083 SDHSEAMVPLAGRGRNVLHVDVHM-PSGFIYWCDYSSTV--------SSQNAIRKIKPD- 2132
Query: 2493 GLIGSWGEEESTAGL-------ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDT 2335
GS+ T G+ I D++ N+YFT + F + I V + T
Sbjct: 2133 ---GSYFRNVVTNGIGRNGIRGIAIDWVAGNLYFTNA--------FLTETFIEVLRLNTT 2181
Query: 2334 STRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKAL 2155
R L+ + + VDP R +FW P+I + LD L
Sbjct: 2182 YRRVLLKTTIDMPRHIVVDPKNRYLFWADYGQNPKIERSFLD-----------CTNRTVL 2230
Query: 2154 VERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGG 1975
V I P + +D SN +YW+D I + DG D VR TP + + G
Sbjct: 2231 VSEGIVTPRGLAIDHSNGYVYWVDDSLDMIARIQPDGGDVEIVRYGSRYPTPYGITIFGN 2290
Query: 1974 YIYLITRQ-GSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQS 1798
+ + R + + K G T++ ++ + + + + S + NPC +
Sbjct: 2291 SMIWVDRNLKKVFQASKEPGNTDQPTVIRDNINWLRDVTIYNSHFQSRSPLDVNNNPCLN 2350
Query: 1797 DY--CPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKC 1684
+ C +PD + P+C C G + K+C
Sbjct: 2351 NNGGCFHLCFALPD-----VQTPQCGCAFGT-LDSDGKRC 2384
Score = 59.3 bits (142), Expect = 1e-06
Identities = 38/132 (28%), Positives = 53/132 (39%), Gaps = 18/132 (13%)
Frame = -1
Query: 6552 CSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCTCNENEFRCQS--------G 6397
C R C P F C NG C+ +C+ NDC + +DE +C FRC S
Sbjct: 1268 CPARTCPPSLFRCDNGNCVYRAWICDGDNDCRDMSDERDCP--TQPFRCPSWQWQCPGHS 1325
Query: 6396 ACIPSKARCNHMQDCNDASDEIG-CPFRNCSALNEFGMT---------GLINCATTSQCI 6247
C+ C++ DC + +DE C +CS N G T C Q
Sbjct: 1326 ICVNLSKVCDNSADCPNGADESPLCNQESCSD-NNAGCTHECIQGPFGAQCTCPVGYQLT 1384
Query: 6246 HPSWKCDGTNDC 6211
+ S C+ N+C
Sbjct: 1385 NDSKTCEDINEC 1396
Score = 59.3 bits (142), Expect = 1e-06
Identities = 98/419 (23%), Positives = 139/419 (32%), Gaps = 45/419 (10%)
Frame = -1
Query: 1821 HQKNPCQSDY--------CPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQLREK 1666
H + C++ Y C N C + D+ G + C P F +C+ LR K
Sbjct: 3723 HTQFSCRTSYRCIPLWAVCNGNDDCRDNSDEQGC--EEMTCSPFGDFRCDNHRCIPLRWK 3780
Query: 1665 DQEASQCGDYFCYNNAGCSPQKT-----------CV-----------CPPGFYGRQCEIN 1552
+ CGD +N CSP++ C+ C R CE+
Sbjct: 3781 CDGDNDCGDQSDEHN--CSPRECTESEYRCDNLRCIPSRWVCDHDDDCEDNSDERDCELR 3838
Query: 1551 ECSETCW--NGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGV-CGPRG-SCKTVPC 1384
C + N C + F N C S+ + +C T G C P CK C
Sbjct: 3839 TCHPGYFQCNSGHCVAERFRCDGNADCLDFSD--EITCPTRYPNGTYCPPMMFECKNHVC 3896
Query: 1383 PKDEPHCRSYSFCECDKGWTGPHCRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLT 1204
+ Y C+ D C +D ++ H AC E P RC
Sbjct: 3897 ------IQPYWKCDGDND-----CGDDSDEEL---HLCLDIAC--ESPFRFRCE------ 3934
Query: 1203 GNRCQNCVGHECLNGGFCSYANSNRSLPHCICPSGFTGDHC--EEYLCKDA--CPFGSKC 1036
NRC HE N S+ HC P T C EE+ C + P C
Sbjct: 3935 NNRC--IYSHELCNQEDDCGDGSDEKEEHCREP---TPRPCTTEEFKCSNGNCIPLHYVC 3989
Query: 1035 TY--DITKPMDPITCSCEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPR 862
D D + C N T IC+ + GG C C P
Sbjct: 3990 DNYDDCGDHFDEMGC----NPGTERTCAENICEHNCTNLNEGGFI---------CSCRPG 4036
Query: 861 FAGPR-----CDVPVQCDDYCTNNSKCTITNGTHFECDCKPGFKGLRCEQETKCSECSN 700
+ CD +C+ + T C + G+ +EC C GFK + +Q +C+ N
Sbjct: 4037 YKASENNRNSCDDINECEIFGTCTQDCKNSKGS-YECFCADGFKSVGDQQGKQCAANGN 4094
Score = 56.2 bits (134), Expect = 1e-05
Identities = 71/266 (26%), Positives = 111/266 (41%), Gaps = 11/266 (4%)
Frame = -1
Query: 2448 ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNS-----TGTINSLA 2284
+ D++ N+Y++ Q+ VL +Y +TLI N GT L
Sbjct: 1828 LALDWISANLYYSNPGTQSIEVLKLHGEVMY--------RKTLITNDGTSLGAGTPIGLT 1879
Query: 2283 VDPIKRLIFWT---TSAPVP-RILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVL 2116
VDP + ++WT T + VP ++ SAN+DG I Q TG+ H + +
Sbjct: 1880 VDPARGKLYWTDQGTDSGVPAKVASANMDGSGI-QTLFTGNLDHVEFI----------TI 1928
Query: 2115 DFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITRQGS-IH 1939
D ++LYW IE + DG +R T+ L P + V ++Y R I
Sbjct: 1929 DIKEQKLYWAVTSTGVIEKGNVDGTNRVTL-VIHLSH-PWGIAVYDTFLYYTDRDYEVIE 1986
Query: 1938 RMHKFTGKTNKYVQKIREVSPRIQ-IRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPD 1762
R+ KFTG NK V +R+ PR++ +RV + S N C ++ +C+P
Sbjct: 1987 RVDKFTG-ANKVV--LRDNVPRLKCLRVYYRDNSAGS-----SNGCSNNIGVCQHLCLP- 2037
Query: 1761 QDKNGILIPKCLCGPGRFFEVSTKKC 1684
G+ C C G + C
Sbjct: 2038 -VPGGLF--SCACATGFQLNPDNRTC 2060
Score = 46.2 bits (108), Expect = 0.011
Identities = 109/487 (22%), Positives = 166/487 (33%), Gaps = 47/487 (9%)
Frame = -1
Query: 1707 FEVSTKKCMQLREKDQEASQCGDYFCYNNAGCSPQKTCVCPPGFYGRQCEINECSETCWN 1528
++ + K+C+ + CGD + C+ + CPPG + +C+ C W
Sbjct: 3641 WQCANKRCIPEAWQCDREDDCGDNSDEDTTHCASR---TCPPGQF--KCDNGRCIPESWK 3695
Query: 1527 ---GETC---AVQEFGSTTNVVCHCPSNYTQSSCATN--------VCEGVCGPRGSCKTV 1390
+ C + + F C N+TQ SC T+ VC G R +
Sbjct: 3696 CDVDDDCGDNSDEPFHECMGPAYRC-DNHTQFSCRTSYRCIPLWAVCNGNDDCRDNSDEQ 3754
Query: 1389 PCPKDEPHCRSYSFCECDKGWTGPHCRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDG 1210
C +E C + CD P R K D G G D C+ +
Sbjct: 3755 GC--EEMTCSPFGDFRCDNHRCIP-LRWKCD-----GDNDCGDQSDEHNCSPRECTESE- 3805
Query: 1209 LTGNRCQN--CVGHE--CLNGGFCSYANSNRSLPHCICPSGF---TGDHC--EEYLCKDA 1057
RC N C+ C + C + R C G+ HC E + C
Sbjct: 3806 ---YRCDNLRCIPSRWVCDHDDDCEDNSDERDCELRTCHPGYFQCNSGHCVAERFRCD-- 3860
Query: 1056 CPFGSKCTYDITKPMDPITCSCEQNAAAHNTDCSPI---CQK----QPNW-CHNGGRCLD 901
G+ D + D ITC + T C P+ C+ QP W C C D
Sbjct: 3861 ---GNADCLDFS---DEITCPTRY---PNGTYCPPMMFECKNHVCIQPYWKCDGDNDCGD 3911
Query: 900 TPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSKCTITNGT-HFECDCKPGF--KGLRCE 730
L C+ P + + N++C ++ + E DC G K C
Sbjct: 3912 DSDEE-----LHLCLDIACESPFR---FRCENNRCIYSHELCNQEDDCGDGSDEKEEHCR 3963
Query: 729 QETKCSECSNEAKCIKKPSGTV--ICQCPQGLGGEY----CEKITATSCHQLECKNGGYC 568
+ T + E KC + +C G + C T +C + C++ C
Sbjct: 3964 EPTPRPCTTEEFKCSNGNCIPLHYVCDNYDDCGDHFDEMGCNPGTERTCAENICEHN--C 4021
Query: 567 LKPDPSANRTSPTCLCSPGFKGLLCSSNACE--NFCLHDGNCTLD---EYFEPQCECYQA 403
+ N C C PG+K + N+C+ N C G CT D +C C
Sbjct: 4022 T----NLNEGGFICSCRPGYKASENNRNSCDDINECEIFGTCTQDCKNSKGSYECFCADG 4077
Query: 402 F--IGDR 388
F +GD+
Sbjct: 4078 FKSVGDQ 4084
Score = 44.3 bits (103), Expect = 0.041
Identities = 48/197 (24%), Positives = 72/197 (36%), Gaps = 31/197 (15%)
Frame = -1
Query: 1803 QSDYCPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQLR---------EKDQEAS 1651
Q+ C + C D+N C G FF + +C+ E +++
Sbjct: 203 QAFMCDHDDDCGDRSDENSCTYATCR---GNFFTCPSGRCIHQSWICDGDDDCEDNEDER 259
Query: 1650 QC---------GDYFCYNNAGCSP-QKTCV----CPPG------FYGRQCEINECSETCW 1531
C G++ C + C P K C CP G GR C I+ C+
Sbjct: 260 GCESSYHECYPGEWACPESGHCIPIGKVCDGAADCPAGEDETNITAGRHCNISHCAAL-- 317
Query: 1530 NGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGV--CGPRGSCKTVPCPKDEPHCRS 1357
+C + S + +C+CPS YT SS + C C G C + C H +
Sbjct: 318 ---SCQYRCHSSPSGGMCYCPSGYTISSNDSRTCIDFDDCKMWGVCDQL-CEDRVGHHQ- 372
Query: 1356 YSFCECDKGWTGPHCRH 1306
C C +G+ H RH
Sbjct: 373 ---CHCVEGYFLEHHRH 386
Score = 42.0 bits (97), Expect = 0.20
Identities = 70/263 (26%), Positives = 91/263 (33%), Gaps = 25/263 (9%)
Frame = -1
Query: 1671 EKDQEASQCGDYFCYNNAGCSPQKTCVCPPGFYGRQCEIN---ECSET---CWNGETCAV 1510
E+D +C C N A + + C E N C+ T C NGE C
Sbjct: 144 ERDCRYPRCEQLSCANGACFNASQRCDGKVDCRDTSDEANCTRGCASTQFQCANGE-CIP 202
Query: 1509 QEFGSTTNVVCHCPSNYTQSSCATNVCEG---VCGPRGSC--KTVPCP--------KDEP 1369
Q F + C S+ ++SC C G C P G C ++ C +DE
Sbjct: 203 QAFMCDHDDDCGDRSD--ENSCTYATCRGNFFTC-PSGRCIHQSWICDGDDDCEDNEDER 259
Query: 1368 HCRSYSFCECDKG-WTGPHCRHKADAKVCYGHCFS-GGACDGEGPLNLRCSCGD---GLT 1204
C S S+ EC G W P GHC G CDG C G+ +T
Sbjct: 260 GCES-SYHECYPGEWACPES----------GHCIPIGKVCDGAAD----CPAGEDETNIT 304
Query: 1203 GNRCQNCVGHECLNGGFCSY-ANSNRSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYD 1027
R N L+ C Y +S+ S C CPSG+T + C D +D
Sbjct: 305 AGRHCNISHCAALS---CQYRCHSSPSGGMCYCPSGYTISSNDSRTCID---------FD 352
Query: 1026 ITKPMDPITCSCEQNAAAHNTDC 958
K CE H C
Sbjct: 353 DCKMWGVCDQLCEDRVGHHQCHC 375
Score = 37.7 bits (86), Expect = 3.8
Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 12/62 (19%)
Frame = -1
Query: 531 TCLCSPGFKGLLCSSNACENF------------CLHDGNCTLDEYFEPQCECYQAFIGDR 388
TC C G + + SS C+ C++ G C +DE P+C+C + GD
Sbjct: 4393 TCACPQGTRFVEGSSTECDAAIESPPTMPPACRCMYGGTCYIDESGLPKCKCSYGYTGDY 4452
Query: 387 CQ 382
C+
Sbjct: 4453 CE 4454
Score = 36.6 bits (83), Expect = 8.5
Identities = 18/40 (45%), Positives = 21/40 (52%)
Frame = -1
Query: 1170 CLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDACP 1051
C+ GG C S LP C C G+TGD+CE L K P
Sbjct: 4426 CMYGGTCYIDESG--LPKCKCSYGYTGDYCEIGLSKGVPP 4463
>gi|1389559|gb|AAB02882.1| glycoprotein 330
Length = 1751
Score = 704 bits (1817), Expect = 0.0
Identities = 539/1821 (29%), Positives = 798/1821 (43%), Gaps = 149/1821 (8%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCT---CNEN-EFRCQ 6403
DE C+ C P F C NG C+ C+ NDC + +DE+ C CN EF C
Sbjct: 26 DEMESVCALHTCSPTAFTCANGRCVQYSYRCDYYNDCGDGSDETGCLFRDCNATTEFMCN 85
Query: 6402 SGACIPSKARCNHMQDCND--ASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKC 6229
+ CIP + CN + +C+D SDE CP R C + G C ++ CI + C
Sbjct: 86 NRRCIPREFICNGVDNCHDNNTSDEKNCPDRTCQS-------GYPKCHNSNICIPRVYLC 138
Query: 6228 DGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQ-CDGQPDC 6052
DG NDC D SDE + +C + ++F C + R C+P+ + CD + DC
Sbjct: 139 DGDNDCGDNSDENPTYC----------TTHTCSS-SEFQCASGR-CIPQTFGICDQETDC 186
Query: 6051 ADGSDEKNC---DAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDE---HQCETECD 5890
D SDE + + C S EF C+ + CIP E CDG DC D DE HQC+ +
Sbjct: 187 FDASDEPSSCGHSERTCLSDEFKCDGGR-CIPNEWICDGDNDCGDMSDEDKRHQCQNQNC 245
Query: 5889 SKGGNATFRCTN-----HRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRC 5725
S ++ F C N RCIP +W DG DC D G DE+ RT C
Sbjct: 246 S---DSEFPCVNDRPPDRRCIPQSWPPDGDVDCTD-----GHDEIQNCTRRTCSENEFTC 297
Query: 5724 ADETCVVACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDAS 5545
C+ CD DC D DE+ C L + C+ N++ C +G+CI +CD
Sbjct: 298 GYGLCIPKI----FRCDRHNDCGDYSDERGC--LYQTCQQNQFTCQNGRCISKTFVCDED 351
Query: 5544 VDCVDGSDEWVEICSLSEPPRRGCPSG-WSCLLTNGTIGCLQEQQLCDGRRDCMSGIDE- 5371
DC DGSDE + +C EP CP + C NG C++ +LC+ DC+ DE
Sbjct: 352 NDCGDGSDELMHLCHTPEPT---CPPHEFKC--DNGR--CIEMMKLCNHLDDCLDNSDEK 404
Query: 5370 -----QCDNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPK 5206
+C +P + + CD NC CSC GY L DK+TC+ C +
Sbjct: 405 GCGINECHDP------SISGCDH--NCTDTLTSFYCSCRPGYKLMS-DKRTCVDIDECTE 455
Query: 5205 AN--CSHFCIDRRDVG-HQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDG 5035
CS C +G + C CAPGY+ + K CR+N IE ++ + L+ TIDG
Sbjct: 456 MPFVCSQKC--ENVIGSYICKCAPGYLREPDGKTCRQNSNIEPYLIFSNRYYLRNLTIDG 513
Query: 5034 HAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINS-LPTKG 4858
+ + +L L N VALD+D +YW D + N+ N +IN LP
Sbjct: 514 YFYSLILEGLDNVVALDFDRVEKRLYWIDTQRQVIER---MFLNKTNKETIINHRLPAA- 569
Query: 4857 IDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTP-------LNDPRAIVLDPL 4699
+ +AVDW+ R +Y+ D D + V D+ G R+L + ++PR + L P
Sbjct: 570 -ESLAVDWVSRKLYWLDARLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLALHPQ 628
Query: 4698 QALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIA 4519
++W DWG A+IGR+ MDG+N+ VI+ + + WPN + +D LY+ DAH YI
Sbjct: 629 YGYLYWADWGHRAYIGRVGMDGTNKSVIISTK-LEWPNGITIDYTNDLLYWADAHLGYIE 687
Query: 4518 SCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQY 4339
+ +G R V G++ H FA+ +FED +YW+DW+ T+E+ +K G+NR+ L+ + +
Sbjct: 688 YSDLEGHHRHTVYDGALPHPFAITIFEDTIYWTDWNTRTVEKGNKYDGSNRQTLV-NTTH 746
Query: 4338 RPMGFKIVHPSLQSMGSLKTARHPC-SQPARCDNLCIPANTPDLTTSSDNFTCMCAQGFR 4162
RP + HP Q + S +PC + C +LC+ + FTC C FR
Sbjct: 747 RPFDIHVYHPYRQPIVS-----NPCGTNNGGCSHLCL------IKPGGKGFTCECPDDFR 795
Query: 4161 ----SEGRSCVSECKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCI 3994
S C+ C F+C KCI WW+ +CP C
Sbjct: 796 TLQLSGSTYCMPMCSSTQFLCANNEKCIPIWWKCDGQKDCSDGSDEL----ALCPQRFCR 851
Query: 3993 AGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCI 3814
GQF C + C LC+ ++C G DE+ CEN C +++C + K+CI
Sbjct: 852 LGQFQC------SDGNCTSPQTLCNAHQNCPDGSDEDRLLCENHHCDSNEWQCAN-KRCI 904
Query: 3813 PLTSVCDKEKDCDDGSDE--LNCEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEG 3640
P + CD DC+D SDE +C +C+P F C NG +CIP+ + CD ++DC +
Sbjct: 905 PESWQCDSFNDCEDNSDEDSSHCASRTCRPGQFRCANG----RCIPQAWKCDVDNDCGDH 960
Query: 3639 QDEP-DSCFGIGEC--THEQFQC-TSGKCIPKRRQCDGTLDCRDGSDEKGC-KKECAIVC 3475
DEP + C +F C T+ +CIPK C+G DCRD SDE+GC ++ C V
Sbjct: 961 SDEPIEECMSSAHLCDNFTEFSCKTNYRCIPKWAVCNGVDDCRDNSDEQGCEERTCHPVG 1020
Query: 3474 D-----NSCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKE----NRKC--GGFACDGI 3328
D + C+ CDG+ C D S DEE C ++ E E N++C + CD
Sbjct: 1021 DFRCKNHHCIPLRWKCDGQNDCGDNS--DEENCAPRECTESEFRCVNQQCIPSRWICDHY 1078
Query: 3327 VDC-EDGSDEKGCPDLECH---------LASNKSLICDGTIDCSSGKDENNCHNN----- 3193
D D SDE+ C CH + L CDG+ DC DE +C
Sbjct: 1079 NDLWGDNSDERDCEMRTCHPEYFQCTSGHRVHSELKCDGSADCLDASDEADCPTRFPDGA 1138
Query: 3192 -GESNFFQCSMQT-IKEWQVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCLDV 3019
++ F+C I + CDG DC DG DE +C CD+ + C+
Sbjct: 1139 YCQATMFECKNHVCIPPYWKCDGDDDCGDGSDEELHLCLDVPCNSPNRFRCDNNR-CI-Y 1196
Query: 3018 STALCDGIRDCFDGSDENPIHC-----KDMCKGKYRCTNGRCI-------DVSARXXXXX 2875
S +C+G+ DC DG+DE HC K + +Y+C NG CI D
Sbjct: 1197 SHEVCNGVDDCGDGTDETEEHCRKPTPKPCTEYEYKCGNGHCIPHDNVCDDADDCGDWSD 1256
Query: 2874 XXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEM 2695
AE +C Q C C C G+ D C +++ E
Sbjct: 1257 ELGCNKGKERTCAE----NICEQNCTQLNEGGFICSCTAGFETNVFDRTSCLDINE-CEQ 1311
Query: 2694 FITNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDI 2515
F T H + + S V F M+ PG + L+ + + ++
Sbjct: 1312 FGTCPQ--HCRNTKGSYECVCADGFT-SMSDRPGK-RCAAEGSSPLLLLPDNVRIRKYNL 1367
Query: 2514 RSKKWSDGLIGSWGEEESTAGLITYDFMHNN-----VYFTESSEQNR------------- 2389
S+++S+ L ++E + YD+ + VY+T E +R
Sbjct: 1368 SSERFSEYL-----QDEEYIQAVDYDWDPEDIGLSVVYYTVRGEGSRFGAIKRAYIPNFE 1422
Query: 2388 ---------------------GVLFD-----------RQANIYVAKAKDTSTRTLIVNST 2305
G+ D + I VAK + LI
Sbjct: 1423 SGRNNLVQEVDLKLKYVMQPDGIAVDWVGRHIYWSDVKNKRIEVAKLDGRYRKWLISTDL 1482
Query: 2304 GTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTS 2125
++AV+P L+FWT P++ SA ++G + LV ++ PT
Sbjct: 1483 DQPAAIAVNPKLGLMFWTDWGKEPKLESAWMNG-----------EDPNILVFEDLGWPTG 1531
Query: 2124 MVLDF-SNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITRQ- 1951
+ +D+ +N+R+YW D + IET+ +DG DRR + K + P ++D+ +Y I+++
Sbjct: 1532 LSIDYLNNDRIYWSDFKEDVIETIKYDGTDRRVIAKEAM--NPYSLDIFEDQLYWISKEK 1589
Query: 1950 GSIHRMHKFTGKTNKYVQKIREVSPRI-QIRVAHPAKHTVSHITHQKNPCQSDYCPSNTV 1774
G + + +KF G+ K +K V+P + Q+R+ H ++ S K C S C
Sbjct: 1590 GEVWKQNKF-GQGKK--EKTLVVNPWLTQVRIFHQLRYNKSVPNLCKQIC-SHLC----- 1640
Query: 1773 CVPDQDKNGILIP---KCLCGPG-RFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCSP 1606
+L P C C G F E ST +C E C + C
Sbjct: 1641 ---------LLRPGGYSCACPQGSSFIEGSTTECDAAIELPINLPP--PCRCMHGGNCYF 1689
Query: 1605 QKT----CVCPPGFYGRQCEI 1555
+T C CP G+ G+ CE+
Sbjct: 1690 DETDLPKCKCPSGYTGKYCEM 1710
Score = 225 bits (574), Expect = 1e-56
Identities = 318/1395 (22%), Positives = 493/1395 (34%), Gaps = 164/1395 (11%)
Frame = -1
Query: 4119 FVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCL 3940
F C+ +CIS W+ +E VC C F C A +C+
Sbjct: 1 FTCSNG-RCISEEWKCDNDNGCGDGSDE---MESVCALHTCSPTAFTC------ANGRCV 50
Query: 3939 YASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDG--S 3766
S CD DC G DE + T +F C +++ CIP +C+ +C D S
Sbjct: 51 QYSYRCDYYNDCGDGSDETGCLFRDCNAT-TEFMCNNRR-CIPREFICNGVDNCHDNNTS 108
Query: 3765 DELNCEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQF 3586
DE NC +C+ + C N CIP+ + CDG++DC + DE + C+ +F
Sbjct: 109 DEKNCPDRTCQSGYPKCHNSNI---CIPRVYLCDGDNDCGDNSDENPTYCTTHTCSSSEF 165
Query: 3585 QCTSGKCIPKRRQ-CDGTLDCRDGSDEKGC----KKECA---IVCDNS-CVHADDLCDGK 3433
QC SG+CIP+ CD DC D SDE ++ C CD C+ + +CDG
Sbjct: 166 QCASGRCIPQTFGICDQETDCFDASDEPSSCGHSERTCLSDEFKCDGGRCIPNEWICDGD 225
Query: 3432 KKCNDGSDEDEE-ACVIKQLLEKE---------NRKC--GGFACDGIVDCEDGSDE-KGC 3292
C D SDED+ C + + E +R+C + DG VDC DG DE + C
Sbjct: 226 NDCGDMSDEDKRHQCQNQNCSDSEFPCVNDRPPDRRCIPQSWPPDGDVDCTDGHDEIQNC 285
Query: 3291 PDLECH---------LASNKSLICDGTIDCSSGKDENNC-HNNGESNFFQCSM-QTIKEW 3145
C L K CD DC DE C + + N F C + I +
Sbjct: 286 TRRTCSENEFTCGYGLCIPKIFRCDRHNDCGDYSDERGCLYQTCQQNQFTCQNGRCISKT 345
Query: 3144 QVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDE- 2968
VCD DC DG DE +C + + C + D +C+++ LC+ + DC D SDE
Sbjct: 346 FVCDEDNDCGDGSDELMHLCHTPEPTCPPHEFKCDNGRCIEMMK-LCNHLDDCLDNSDEK 404
Query: 2967 ----NPIHCKDMCKGKYRCTNGRCIDVSARXXXXXXXXXXXXXXXXGAECHHFG-VCAQK 2803
N H + + CT+ EC VC+QK
Sbjct: 405 GCGINECHDPSISGCDHNCTD-TLTSFYCSCRPGYKLMSDKRTCVDIDECTEMPFVCSQK 463
Query: 2802 CWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQVSVLRPV 2623
C C CAPGY R + D C + + E ++ NR +L +L ++
Sbjct: 464 CENVIGSYI-CKCAPGYLR-EPDGKTCRQ-NSNIEPYLIFSNRYYLRNL-----TIDGYF 515
Query: 2622 FNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVD--IRSKKWSDGLIGSWGEEESTAGL 2449
+++ + + + +D L Y + ++ +K + +I A
Sbjct: 516 YSLILEGLDNVVALDFDRVEKRL-YWIDTQRQVIERMFLNKTNKETII---NHRLPAAES 571
Query: 2448 ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINS------- 2290
+ D++ +Y+ ++ R ++V+ R L + N+
Sbjct: 572 LAVDWVSRKLYWLDA----------RLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPR 621
Query: 2289 -LAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLD 2113
LA+ P ++W I +DG ++ + P + +D
Sbjct: 622 GLALHPQYGYLYWADWGHRAYIGRVGMDG-----------TNKSVIISTKLEWPNGITID 670
Query: 2112 FSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT-RQGSIHR 1936
++N+ LYW D IE +G R TV L P + + IY ++ +
Sbjct: 671 YTNDLLYWADAHLGYIEYSDLEGHHRHTVYDGAL-PHPFAITIFEDTIYWTDWNTRTVEK 729
Query: 1935 MHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQD 1756
+K+ G + + + I V HP + + NPC ++ + +C+
Sbjct: 730 GNKYDGSNRQTL--VNTTHRPFDIHVYHPYRQPI-----VSNPCGTNNGGCSHLCLIKPG 782
Query: 1755 KNGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCG--DYFCYNNAGCSP-------Q 1603
G C C P F + +QL C + C NN C P Q
Sbjct: 783 GKGF---TCEC-PDDF------RTLQLSGSTYCMPMCSSTQFLCANNEKCIPIWWKCDGQ 832
Query: 1602 KTC--------VCPPGFYGRQCEINECSETCWNGETCAVQEFGSTTNVVCHCP--SNYTQ 1453
K C +CP F C + + C +G + Q + N +CP S+ +
Sbjct: 833 KDCSDGSDELALCPQRF----CRLGQFQ--CSDGNCTSPQ---TLCNAHQNCPDGSDEDR 883
Query: 1452 SSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHKADAKVCYGHC 1273
C + C+ C C + C S++ CE + HC + + C
Sbjct: 884 LLCENHHCD---SNEWQCANKRCIPESWQCDSFNDCEDNSDEDSSHCASRT-CRPGQFRC 939
Query: 1272 FSGGACDGEGPLNLRCSCGDGLTGNRCQNCV--GHECLNGGFCSYANSNRSLPHCI---- 1111
+G ++ CGD + + C+ H C N S + R +P
Sbjct: 940 ANGRCIPQAWKCDVDNDCGDH-SDEPIEECMSSAHLCDNFTEFSCKTNYRCIPKWAVCNG 998
Query: 1110 ---CPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCSCE-QNAAAHNTD---CSP 952
C CEE C F K + I P+ C+ QN N+D C+P
Sbjct: 999 VDDCRDNSDEQGCEERTCHPVGDFRCKNHHCI-----PLRWKCDGQNDCGDNSDEENCAP 1053
Query: 951 -----------------------------------------ICQKQPNWCHNGGRCLDTP 895
C + C +G R
Sbjct: 1054 RECTESEFRCVNQQCIPSRWICDHYNDLWGDNSDERDCEMRTCHPEYFQCTSGHRVHSEL 1113
Query: 894 GYPGKCKCLPRFAGPRCDVPVQCDD--YCTNNSKCTITNGTHFECD---CKPGFKGLRCE 730
G CL A D P + D YC T FEC C P + +C+
Sbjct: 1114 KCDGSADCLD--ASDEADCPTRFPDGAYC---------QATMFECKNHVCIPPY--WKCD 1160
Query: 729 QETKCSECSNEA--KCIKKPSGT---------------VIC----QCPQGLG--GEYCEK 619
+ C + S+E C+ P + +C C G E+C K
Sbjct: 1161 GDDDCGDGSDEELHLCLDVPCNSPNRFRCDNNRCIYSHEVCNGVDDCGDGTDETEEHCRK 1220
Query: 618 ITATSCHQLECKNG-GYCLKPD------PSANRTSPTCLCSPGFKGLLCSSNACENFC-- 466
T C + E K G G+C+ D S C+ G K C+ N CE C
Sbjct: 1221 PTPKPCTEYEYKCGNGHCIPHDNVCDDADDCGDWSDELGCNKG-KERTCAENICEQNCTQ 1279
Query: 465 LHDGN--CTLDEYFE 427
L++G C+ FE
Sbjct: 1280 LNEGGFICSCTAGFE 1294
Score = 140 bits (353), Expect = 4e-31
Identities = 103/321 (32%), Positives = 142/321 (44%), Gaps = 35/321 (10%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDC-ANFADESNC---TCNENEFRC 6406
D+ D + C+ R C F C N CIP + +C+ ND + +DE +C TC+ F+C
Sbjct: 1044 DNSDEENCAPRECTESEFRCVNQQCIPSRWICDHYNDLWGDNSDERDCEMRTCHPEYFQC 1103
Query: 6405 QSGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCD 6226
SG + S+ +C+ DC DASDE CP R + + C CI P WKCD
Sbjct: 1104 TSGHRVHSELKCDGSADCLDASDEADCPTRFPD--GAYCQATMFEC-KNHVCIPPYWKCD 1160
Query: 6225 GTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCAD 6046
G +DC DGSDE + + D C++ +F C R C+ H C+G DC D
Sbjct: 1161 GDDDCGDGSDE-ELHLCLDV---------PCNSPNRFRCDNNR-CIYSHEVCNGVDDCGD 1209
Query: 6045 GSD--EKNC---DAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGED------------ 5917
G+D E++C K CT +E+ C + CIP + CD DC D D
Sbjct: 1210 GTDETEEHCRKPTPKPCTEYEYKC-GNGHCIPHDNVCDDADDCGDWSDELGCNKGKERTC 1268
Query: 5916 -EHQCETECDS-KGGNATFRCT---------NHRCIPMAWRCDGTDDCMDNAKSL-GSDE 5773
E+ CE C G CT C+ + C+ C + ++ GS E
Sbjct: 1269 AENICEQNCTQLNEGGFICSCTAGFETNVFDRTSCLDIN-ECEQFGTCPQHCRNTKGSYE 1327
Query: 5772 VDCAAGRTSF--HVPSRCADE 5716
CA G TS RCA E
Sbjct: 1328 CVCADGFTSMSDRPGKRCAAE 1348
Score = 79.7 bits (195), Expect = 9e-13
Identities = 37/95 (38%), Positives = 48/95 (49%), Gaps = 7/95 (7%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADE-------SNCTCNENE 6415
D D + C + C+ F C NG CI + VC+ NDC + +DE TC +E
Sbjct: 317 DYSDERGCLYQTCQQNQFTCQNGRCISKTFVCDEDNDCGDGSDELMHLCHTPEPTCPPHE 376
Query: 6414 FRCQSGACIPSKARCNHMQDCNDASDEIGCPFRNC 6310
F+C +G CI CNH+ DC D SDE GC C
Sbjct: 377 FKCDNGRCIEMMKLCNHLDDCLDNSDEKGCGINEC 411
Score = 60.1 bits (144), Expect = 7e-07
Identities = 73/309 (23%), Positives = 99/309 (31%), Gaps = 93/309 (30%)
Frame = -1
Query: 5679 CDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASVDCVDGSDE------ 5518
CD C DG DE C P + C +G+C+ CD DC DGSDE
Sbjct: 15 CDNDNGCGDGSDEMESVCALHTCSPTAFTCANGRCVQYSYRCDYYNDCGDGSDETGCLFR 74
Query: 5517 -----------------------WVEICSLSEP------PRRGCPSGW-SCLLTNGTIGC 5428
V+ C + P R C SG+ C +N C
Sbjct: 75 DCNATTEFMCNNRRCIPREFICNGVDNCHDNNTSDEKNCPDRTCQSGYPKCHNSN---IC 131
Query: 5427 LQEQQLCDGRRDCMSGIDEQ--------CDNPQGNCSSTR------NSCDQTWNC----- 5305
+ LCDG DC DE C + + C+S R CDQ +C
Sbjct: 132 IPRVYLCDGDNDCGDNSDENPTYCTTHTCSSSEFQCASGRCIPQTFGICDQETDCFDASD 191
Query: 5304 --------QRHAGFESCSCDDGY---------------HLSPYDKKTCLRSPSCPKANCS 5194
+R + CD G +S DK+ C NCS
Sbjct: 192 EPSSCGHSERTCLSDEFKCDGGRCIPNEWICDGDNDCGDMSDEDKR-----HQCQNQNCS 246
Query: 5193 HF---CIDRRDVGHQCF-----------CAPGYILSENQKDCRRNDTIEAEILMVYGHRL 5056
C++ R +C C G+ + ++C R E E YG +
Sbjct: 247 DSEFPCVNDRPPDRRCIPQSWPPDGDVDCTDGH---DEIQNCTRRTCSENEFTCGYGLCI 303
Query: 5055 -KLFTIDGH 5032
K+F D H
Sbjct: 304 PKIFRCDRH 312
Score = 52.8 bits (125), Expect = 1e-04
Identities = 43/153 (28%), Positives = 60/153 (39%), Gaps = 14/153 (9%)
Frame = -1
Query: 5592 CDSGQCIDSGRLCDASVDCVDGSDEWVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQ 5413
C +G+CI CD C DGSDE +C+L P+ ++C NG C+Q
Sbjct: 3 CSNGRCISEEWKCDNDNGCGDGSDEMESVCAL----HTCSPTAFTC--ANGR--CVQYSY 54
Query: 5412 LCDGRRDCMSGIDE--------------QCDNPQGNCSSTRNSCDQTWNCQRHAGFESCS 5275
CD DC G DE C+N + C C+ NC + + +
Sbjct: 55 RCDYYNDCGDGSDETGCLFRDCNATTEFMCNNRR--CIPREFICNGVDNCHDNNTSDEKN 112
Query: 5274 CDDGYHLSPYDKKTCLRSPSCPKANCSHFCIDR 5176
C D +TC PK + S+ CI R
Sbjct: 113 CPD---------RTC--QSGYPKCHNSNICIPR 134
Score = 40.4 bits (93), Expect = 0.59
Identities = 17/40 (42%), Positives = 24/40 (59%)
Frame = -1
Query: 1170 CLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDACP 1051
C++GG C + ++ LP C CPSG+TG +CE K P
Sbjct: 1681 CMHGGNCYFDETD--LPKCKCPSGYTGKYCEMAFSKGISP 1718
Score = 38.5 bits (88), Expect = 2.2
Identities = 24/83 (28%), Positives = 36/83 (42%), Gaps = 1/83 (1%)
Frame = -1
Query: 627 CEKITATSCHQLECKNGGY-CLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCLHDGN 451
C++I + C + GGY C P S+ T C + + C C+H GN
Sbjct: 1632 CKQICSHLCL---LRPGGYSCACPQGSSFIEGSTTECDAAIELPINLPPPCR--CMHGGN 1686
Query: 450 CTLDEYFEPQCECYQAFIGDRCQ 382
C DE P+C+C + G C+
Sbjct: 1687 CYFDETDLPKCKCPSGYTGKYCE 1709
>gi|50750792|ref|XP_422146.1| PREDICTED: similar to Low-density
lipoprotein receptor-related protein 1B precursor
(Low-density lipoprotein receptor-related protein-deleted
in tumor) (LRP-DIT) [Gallus gallus]
Length = 3738
Score = 701 bits (1810), Expect = 0.0
Identities = 533/1813 (29%), Positives = 792/1813 (43%), Gaps = 120/1813 (6%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC---TCNENEFRCQS 6400
DE YC R CR G+ C N CI KVC+ NDC + +DE +C C EFRC
Sbjct: 1604 DEKLFYCENRGCRKGFKPCSNRRCISRNKVCDGRNDCGDNSDEIDCKDSACTSTEFRCAD 1663
Query: 6399 GACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGM--TGLINCATTSQCIHPSWKCD 6226
G CI A+CN + DC DASDE C NC+ + G+ TG I+C +TS CI P W CD
Sbjct: 1664 GTCIGKSAQCNQIIDCADASDEKNCNNTNCAYFYKLGIKSTGFISCNSTSLCILPEWICD 1723
Query: 6225 GTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCAD 6046
G+NDC D +DE C V+ T C+ + F C + R C+ W CDGQ DC D
Sbjct: 1724 GSNDCGDYTDELKCPVQNKPT---------CE-ENYFGCPSGR-CILNTWLCDGQKDCED 1772
Query: 6045 GSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQ--CETECDSKGGNA 5872
G DE +CD+ C+ +F+C S+ KCI + CDG DC +G DE C + + G
Sbjct: 1773 GVDELHCDSS-CSWNQFAC-SADKCISKQWTCDGEDDCGNGLDESDAICGSVTCAVG--- 1827
Query: 5871 TFRCT-NHRCIPMAWRCDGTDDCMDNAKSLGSDEVD---CAAGRTSFHVPSRCADETCVV 5704
TF C +H C+P W CDG DC + GSDE+ CA T C + C+
Sbjct: 1828 TFSCLGSHACVPHHWLCDGERDCPN-----GSDELSTAGCAPNNTCDENAFMCRNNICIP 1882
Query: 5703 ACELTAVLCDGIQDCSDGFDEK-NCASLD---RQCKPNEWMCDSGQCI-DSGRLCDASVD 5539
+CD DC DG DE C + R+C P E+ C G+C+ +S CD D
Sbjct: 1883 K----QFVCDHDDDCGDGSDESLECGKYNKRYRRCHPGEFTCADGRCLLNSQWQCDGDFD 1938
Query: 5538 CVDGSDEWVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDN 5359
C D SDE I + + C S + + NG C+ + +C+ + DC G DE+ +
Sbjct: 1939 CPDHSDE-APINKKCKSSEQSCNSSFF-MCKNGK--CIPQNNVCNNKEDCSDGSDEKSCH 1994
Query: 5358 PQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKA-NCSHFCI 5182
S + C Q +CQ C C G+ L D KTC C CS CI
Sbjct: 1995 INECLSKKVSGCSQ--DCQDLPVGYKCKCWPGFQLKD-DGKTCTDIDECSSGFPCSQQCI 2051
Query: 5181 DRRDVGHQCFCAPGY-ILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNL 5005
+ ++C CA GY I +N C+ E +++ H ++ + DG L L
Sbjct: 2052 NTYGT-YKCLCADGYEIQPDNLNGCKSLSDEEPFLILADHHEIRKISTDGSNYTLLKQGL 2110
Query: 5004 TNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGR 4825
N +A+D+D + + +YW D + N + I M + +V+++ T + +AVDW+G+
Sbjct: 2111 NNVIAIDFDYREEFIYWIDSSRP-NGSRINRMRLNGSDIKVVHN--TAVPNALAVDWIGK 2167
Query: 4824 NIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRM 4645
N+Y++D I V + G + +L+ + PR + LDP ++W D HIGR+
Sbjct: 2168 NLYWSDTEKRIIEVSKVNGLYPTVLVSKR-VKFPRDLSLDPQAGYLYWIDCCEYPHIGRV 2226
Query: 4644 NMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVR 4465
MDGS++ V+++ + R P AL +D RLY+ D ++I + DGS R V +
Sbjct: 2227 GMDGSSQTVVIETQISR-PMALTIDYVNHRLYWAD--ENHIEFSDMDGSHRHKVPNQDIP 2283
Query: 4464 HIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSL 4285
+ AL +FEDY+YW+D ++ R HK +G +R LI + + ++ H Q
Sbjct: 2284 GVIALTLFEDYIYWTDGKTKSLNRAHKTSGLDRLSLI-NSWHTITDIQVYHSYRQP---- 2338
Query: 4284 KTARHPCS-QPARCDNLCIPANTPDLTTSSDNFTCMCAQGF--RSEGRSCVSECKPNDFV 4114
++H C+ C +LC+ A TC C F ++ ++C+S C + F
Sbjct: 2339 DVSKHLCTVNNGGCSHLCLLA-------PGKMHTCACPTNFYLAADNKTCLSNCTASQFR 2391
Query: 4113 CTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYA 3934
C KT KCI WW+ CP F C G+F CG T C
Sbjct: 2392 C-KTDKCIPFWWKCDTVDDCGDGSDE----PEECPEFRCQPGRFQCG------TGLCALP 2440
Query: 3933 SKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELN 3754
+ +CDG DC GD+ + C+ C QFKC +KCIP+ C+ + DC D DE +
Sbjct: 2441 AFICDGENDC--GDNSDELNCDTHVCLSGQFKCTKNQKCIPINLRCNGQDDCGDEEDERD 2498
Query: 3753 CEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTS 3574
C SC PD F C CI K + CD + DC +G DE + C +FQC +
Sbjct: 2499 CPENSCSPDHFQC---QTTKHCISKLWVCDEDPDCADGSDEANC--DKKTCGPHEFQCKN 2553
Query: 3573 GKCIPKRRQCDGTLDCRDGSDEKGCKKE-CAI---VCDN-SCVHADDLCDGKKKCNDGSD 3409
CIP +CD DC D SDE+ CK + C + +C N CV A CDG C DGSD
Sbjct: 2554 NNCIPDHWRCDSQNDCGDNSDEENCKPQTCTLKDFLCANGDCVSARFWCDGDYDCADGSD 2613
Query: 3408 ED--EEACVIKQLLEKENRKC--GGFACDGIVDCEDGSDEKGCPDLE--CHLAS------ 3265
E E C Q + N +C + CDG DC+ G DEK C C ++
Sbjct: 2614 ERYCETGCSRDQ-FQCSNGQCISAKWRCDGHEDCKLGDDEKNCEPASPTCSVSEYICASG 2672
Query: 3264 ---NKSLICDGTIDCSSGKDENNCHNNGESNFFQCSMQT--IKEWQVCDGRWDCADGLDE 3100
+ SL C+G DC+ G DE +C + + F+C + I +CDG DC DG DE
Sbjct: 2673 GCISASLKCNGEYDCADGSDEMDCVTECKEDQFRCKNKAYCIPVRWLCDGIHDCVDGSDE 2732
Query: 3099 SP----------EMCASRKARCF-----RIGYCDDKKQCLDVSTALCDGIRDCFDGSDEN 2965
CA ++ F R C + + CL +C+ + DC D SDE+
Sbjct: 2733 EDCVQGCVLIGIVFCAIKETIKFPCPPTRPYRCRNNRVCLR-PEQICNEVDDCGDNSDED 2791
Query: 2964 PIHCKDMC-------KGKYRCTNGRCIDVSAR-----XXXXXXXXXXXXXXXXGAECH-H 2824
HC + K ++ C + +CI + + C +
Sbjct: 2792 --HCDKITYKARPCKKDEFTCNDKKCIPMELQCDWFDDCGDGSDEQDCKISVTEYTCEDN 2849
Query: 2823 FGVCAQKCWMAFNHTA-RCHCAPGYARTK-----NDENECEPL----------------- 2713
C + T+ C C PG+ R + D NEC
Sbjct: 2850 VNPCGDDAYCNQTKTSLLCQCKPGFQRNEMNRQCEDINECMVFGACSQHCNNVKGSYRCA 2909
Query: 2712 ----------------SKSAEMFITNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDF 2581
S+ +++ N + + + V + + +I+ N G+D
Sbjct: 2910 CEKNYKEWNNSCKAKGSEEQVLYVANDTDILGFAYPFNYSDVHQQISHIEHNSRITGMDA 2969
Query: 2580 ---GYDVFRTTLMYTVGIGNSRVDIRSKKWSD-GLIGSWGEEESTAGLITYDFMHNNVYF 2413
G + +T GI ++ + K+ S+ GLI E + G I D++ N+Y+
Sbjct: 2970 YFQGNMIVWSTHFNPGGIFYKKLHDKEKRQSNSGLI--CPEFKRPRG-IAVDWIAGNIYW 3026
Query: 2412 TESSEQNRGVLF-----DRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTT 2248
T+ S + + + +I V + + L+ + G ++AV+P K +++WT
Sbjct: 3027 TDHSRMHWFSYYTTHWTSLRYSINVGQLNGPNCTRLLTSIAGEPYAIAVNPKKGMMYWTV 3086
Query: 2247 SAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRT 2068
I +++DG + LV++N+ PT +V+D ++RL+W D
Sbjct: 3087 IGDRSHIEESSMDG-----------TLRRILVQKNLQRPTGLVVDQFSQRLFWADFELSV 3135
Query: 2067 IETVSFDGRDRRTVRKFELGDT-PVTMDVLGGYIYLITRQGSIHRMHKFTGKTNKYVQKI 1891
I +V FDG D + G P +D+ YIY + R+HKF +Y+
Sbjct: 3136 IGSVLFDGSDSVVSVSTKQGLLHPHRIDIFEDYIYGAGPKNGAFRVHKFGRSLVEYLSV- 3194
Query: 1890 REVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLCGPGR 1711
+V + H K NPC C + P C C G+
Sbjct: 3195 -DVDKAKSALIFHRYKQ-----MDLPNPCLDLTCEFICLLNPSG-------ASCACPEGK 3241
Query: 1710 FFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCSPQKTCVCPPGFYGRQCEINECSETCW 1531
T L + + + C N P+ C C P + G +CE N C C
Sbjct: 3242 SLVNGTCVDQSLLDDTCKLTCENGGKCIINEKGDPR--CHCWPSYSGERCETNHCYNYCQ 3299
Query: 1530 NGETCAVQEFGST 1492
NG TC G+T
Sbjct: 3300 NGGTCGASLLGAT 3312
Score = 377 bits (967), Expect = e-102
Identities = 250/728 (34%), Positives = 346/728 (47%), Gaps = 18/728 (2%)
Frame = -1
Query: 6429 CNENEFRCQSGACIPSKARCNHMQDCNDASDE-IGCPFRNCSALNEFGMTGLINCATTSQ 6253
C +F+C + CI + RC+ DC D SDE F + N+F ++
Sbjct: 6 CKAEQFQCNNKRCIHDRWRCDGDDDCLDGSDEHADICFNHSCPENQFK-------CQNNR 58
Query: 6252 CIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQ 6073
CI W CDG NDC + DE + A R+C QF+C R C+P W
Sbjct: 59 CIPKRWLCDGANDCGNNEDESN----------KTCAARTCQFD-QFSCGNGR-CIPTSWL 106
Query: 6072 CDGQPDCADGSDEK-NCDAKKCTSF-EFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCET 5899
CD + DC D +DE +C+ C +F C++ + CI + CD DC DG DE C
Sbjct: 107 CDREDDCGDQTDEMTSCEFPTCEPLTQFICKNGR-CISSKWLCDSDDDCGDGSDELGCIH 165
Query: 5898 ECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCAD 5719
C + FRC N RCIP W CDG +DC D SDE + P RC
Sbjct: 166 SCSAD----QFRCYNGRCIPSHWACDGDNDCGDY-----SDETRTNCTKEETPAPGRCNG 216
Query: 5718 ETCVVACELTAV----LCDGIQDCSDGFDEKNCASLDRQC-KPNEWMCDS-GQCIDSGRL 5557
+ + + V CDG +DC DG DEK C R C + ++ C S G+CI L
Sbjct: 217 KEFQCSPDGNCVPELWRCDGEKDCEDGSDEKGCNGTLRLCDEKTKFSCVSTGRCISKAWL 276
Query: 5556 CDASVDCVDGSDEWVEICS--LSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMS 5383
CD +DC D SDE + C + PP+ C N T CLQ ++LC+GRRDC
Sbjct: 277 CDGDIDCEDQSDE--DNCEGYMCGPPKYPC--------ANDTSICLQPEKLCNGRRDCPD 326
Query: 5382 GIDEQ--CDNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCP 5209
G DE CD CS C + G CSC G++LS D KTC C
Sbjct: 327 GSDEGDLCDE----CSLNNGGCSHQCSVVP-GGRIVCSCPSGFNLS-VDNKTCEIMDYCT 380
Query: 5208 K-ANCSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGH 5032
K CS C ++ +C C G+ LS++ ++C D EA I+ H ++ +
Sbjct: 381 KHLKCSQVCEQHKN-NVKCSCYEGWKLSKDGENCISTDPFEAFIIFSIRHEIRKIDLHKR 439
Query: 5031 AKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGID 4852
+ L+ L N +ALD+ L+YWTDV D G S + + VI +
Sbjct: 440 DYSLLVPGLRNTIALDFHFSQSLLYWTDVVEDKIYRGKLSDTGGVSAIEVIVQHGLATPE 499
Query: 4851 GIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDW 4672
G+ VDW+ NIY+ D N D I V + G L+ G + PRAI LDP ++FWTDW
Sbjct: 500 GLTVDWIAGNIYWIDSNLDQIEVAKLDGTLRTTLIAGA-MEHPRAIALDPRYGILFWTDW 558
Query: 4671 GAS-AHIGRMNMDGSNEQVILQDR-TIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGS 4498
A+ I +M G+ ++I +D T WPN L VD +R+ + DA D I S YDG+
Sbjct: 559 DANFPRIESASMSGAERKIIYKDMDTGAWPNGLTVDHFEKRIVWTDARSDAIYSALYDGT 618
Query: 4497 KRRMVLRGS--VRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGF 4324
++RG + H FA++++ VYW+DW +T+ + +K TG N V IQ +P
Sbjct: 619 GMIEIIRGHEYLSHPFAVSLYGSEVYWTDWRTNTLAKANKWTGQNVSV-IQKTSAQPFDL 677
Query: 4323 KIVHPSLQ 4300
+I HPS Q
Sbjct: 678 QIYHPSRQ 685
Score = 359 bits (921), Expect = 6e-97
Identities = 432/1729 (24%), Positives = 645/1729 (36%), Gaps = 146/1729 (8%)
Frame = -1
Query: 5214 CPKAN--CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTI 5041
C K N C C+ R C CA GY L+E+ C R+ E ++Y R L +I
Sbjct: 1210 CAKNNGGCHQLCLYRGKAQRTCACAHGY-LAEDGITCLRH-----EGYLLYSGRTILKSI 1263
Query: 5040 DGHAKATLLSNLTN-----------GVALDYDVK---SDLVYWTDVAHDGNKAGITSMSN 4903
+ L S + +A DY +K ++ ++++D AH GN I N
Sbjct: 1264 HLSDENNLNSPVRPYENPEYFKNVIALAFDYSLKGRGTNRIFFSD-AHFGNIQVIKD--N 1320
Query: 4902 QPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDM----RGRFNRILLKGTP 4735
+I ++ + ++G+A +Y+T +I + RG FNR +
Sbjct: 1321 WAGRRVLIENVGS--VEGLAYHRAWDTLYWTSSTTSSITRHTVDQRRRGAFNREAVITMS 1378
Query: 4734 LND-PRAIVLDPLQALVFWTDWGASA-HIGRMNMDGSNEQVILQDRTIRWPNALAVDAPA 4561
+D P + LD Q L+FWT+W I R + G N QVI+ I PN L +D A
Sbjct: 1379 EDDHPHVLALDECQNLMFWTNWNEQLPSIMRSTLSGKNAQVIIST-DILTPNGLTIDHRA 1437
Query: 4560 QRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKI 4381
++LYF D I C YDGS+R ++++ +LAV++DY++WSD I R K
Sbjct: 1438 EKLYFSDGSLGKIERCEYDGSQRYVIVKSGPGTFLSLAVYDDYIFWSDGVRRAILRSSKY 1497
Query: 4380 TGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQP-ARCDNLCIPANTPDLTT 4204
TG + KVL D ++PMG V S PC+Q C +LC L T
Sbjct: 1498 TGGDTKVLRSDIPHQPMGIIAVANDTNSC-----ELSPCAQMNGGCHDLC-------LLT 1545
Query: 4203 SSDNFTCMCAQGFRS--EGRSCVSECKP----NDFVCTKTYKCISSWWRXXXXXXXXXXX 4042
C C +G R + CV++ ++F C +CI
Sbjct: 1546 PDGRVNCSC-RGDRILIDDNRCVTKNSTCNIYSEFECGNG-ECIDYQLTCDGTAHCKDKS 1603
Query: 4041 XXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENF 3862
F C C G C + +C+ +K+CDG DC GD+ + C++
Sbjct: 1604 DEKLFY---CENRGCRKGFKPC------SNRRCISRNKVCDGRNDC--GDNSDEIDCKDS 1652
Query: 3861 ECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSC--------KPDFFACFNG 3706
CT +F+C D CI ++ C++ DC D SDE NC T+C K F N
Sbjct: 1653 ACTSTEFRCADGT-CIGKSAQCNQIIDCADASDEKNCNNTNCAYFYKLGIKSTGFISCNS 1711
Query: 3705 TAISKCIPKEFYCDGEDDCPEGQDEPDSCF-GIGECTHEQFQCTSGKCIPKRRQCDGTLD 3529
T++ CI E+ CDG +DC + DE C F C SG+CI CDG D
Sbjct: 1712 TSL--CILPEWICDGSNDCGDYTDELKCPVQNKPTCEENYFGCPSGRCILNTWLCDGQKD 1769
Query: 3528 CRDGSDEKGCKKECA---IVCD-NSCVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKEN 3361
C DG DE C C+ C + C+ CDG+ C +G DE + C
Sbjct: 1770 CEDGVDELHCDSSCSWNQFACSADKCISKQWTCDGEDDCGNGLDESDAICGSVTCAVGTF 1829
Query: 3360 RKCGGFAC-------DGIVDCEDGSDE---KGC-PDLEC---------HLASNKSLICDG 3241
G AC DG DC +GSDE GC P+ C ++ K +CD
Sbjct: 1830 SCLGSHACVPHHWLCDGERDCPNGSDELSTAGCAPNNTCDENAFMCRNNICIPKQFVCDH 1889
Query: 3240 TIDCSSGKDEN-----------NCHNNGESNFFQCSMQTIKEWQVCDGRWDCADGLDESP 3094
DC G DE+ CH GE +WQ CDG +DC D DE+P
Sbjct: 1890 DDDCGDGSDESLECGKYNKRYRRCHP-GEFTCADGRCLLNSQWQ-CDGDFDCPDHSDEAP 1947
Query: 3093 --EMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKGKYRCT 2920
+ C S + C + +C+ + +C+ DC DGSDE H + K
Sbjct: 1948 INKKCKSSEQSCNSSFFMCKNGKCIPQNN-VCNNKEDCSDGSDEKSCHINECLSKKVSGC 2006
Query: 2919 NGRCIDV----SARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGY 2752
+ C D+ + EC C+Q+C + T +C CA GY
Sbjct: 2007 SQDCQDLPVGYKCKCWPGFQLKDDGKTCTDIDECSSGFPCSQQCINTYG-TYKCLCADGY 2065
Query: 2751 ARTKNDENECEPLSKSAEMFI-TNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGY 2575
++ N C+ LS I + + + +S + S ++L+ N N+I IDF Y
Sbjct: 2066 EIQPDNLNGCKSLSDEEPFLILADHHEIRKISTDGSNYTLLKQGLN---NVI--AIDFDY 2120
Query: 2574 DVFRTTLMYTVGIGN---SRVDIRSKKWSDGLIGSWGEEESTAGLITYDFMHNNVYFTES 2404
R +Y + SR++ SD + + + D++ N+Y++++
Sbjct: 2121 ---REEFIYWIDSSRPNGSRINRMRLNGSDIKVV---HNTAVPNALAVDWIGKNLYWSDT 2174
Query: 2403 SEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRIL 2224
++ I V+K L+ L++DP ++W P I
Sbjct: 2175 EKRI----------IEVSKVNGLYPTVLVSKRVKFPRDLSLDPQAGYLYWIDCCEYPHIG 2224
Query: 2223 SANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDG 2044
+DG ++E I P ++ +D+ N RLYW D + IE DG
Sbjct: 2225 RVGMDGSS-----------QTVVIETQISRPMALTIDYVNHRLYWAD--ENHIEFSDMDG 2271
Query: 2043 RDRRTVRKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGKTNKYVQKIREVSPRIQ 1867
R V ++ + + + YIY + S++R HK +G + IQ
Sbjct: 2272 SHRHKVPNQDIPGV-IALTLFEDYIYWTDGKTKSLNRAHKTSGLDRLSLINSWHTITDIQ 2330
Query: 1866 IRVAHPAKHTVSHITHQKN------------PCQSDYCPSNTVCVPDQDKNGILIPKCLC 1723
+ ++ H+ N + CP+N D N + C
Sbjct: 2331 VYHSYRQPDVSKHLCTVNNGGCSHLCLLAPGKMHTCACPTNFYLAAD---NKTCLSNCTA 2387
Query: 1722 GPGRFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCSPQKTCV---CPPGFYGRQCEIN 1552
F T KC+ K CGD G + C C PG + QC
Sbjct: 2388 SQ---FRCKTDKCIPFWWKCDTVDDCGD-------GSDEPEECPEFRCQPGRF--QCGTG 2435
Query: 1551 ECSETCW--NGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPK 1378
C+ + +GE C N + +C T+VC + G K C
Sbjct: 2436 LCALPAFICDGEN--------------DCGDNSDELNCDTHVC--LSGQFKCTKNQKCIP 2479
Query: 1377 DEPHCRSYSFC-------ECDKGWTGPHCRHKADAKVCYGHCFSG-GACDGEGPLNLRCS 1222
C C +C + P K HC S CD E P
Sbjct: 2480 INLRCNGQDDCGDEEDERDCPENSCSPDHFQCQTTK----HCISKLWVCD-EDP-----D 2529
Query: 1221 CGDGLTGNRC--QNCVGHECLNGGFCSYANSNRSLPHCICPS-GFTGDHCEEYLCK-DAC 1054
C DG C + C HE N+N H C S GD+ +E CK C
Sbjct: 2530 CADGSDEANCDKKTCGPHE------FQCKNNNCIPDHWRCDSQNDCGDNSDEENCKPQTC 2583
Query: 1053 PFGSKCTYDITKPMDPITCSCEQNAAAHNTD--CSPICQKQPNWCHNGGRCLDT----PG 892
+ C + + A + + C C + C N G+C+ G
Sbjct: 2584 TLKDFLCANGDCVSARFWCDGDYDCADGSDERYCETGCSRDQFQCSN-GQCISAKWRCDG 2642
Query: 891 YPGKCK-------CLPRFAGPRCDVPVQCDDYCTNNSKCTITNGTHFECDCKPGFKGLRC 733
+ CK C P A P C V + C + + + + E DC G + C
Sbjct: 2643 HE-DCKLGDDEKNCEP--ASPTCSV---SEYICASGGCISASLKCNGEYDCADGSDEMDC 2696
Query: 732 EQETKCSE--CSNEAKCIKK----------PSGTVICQCPQG---LGGEYCE-----KIT 613
E K + C N+A CI G+ C QG +G +C K
Sbjct: 2697 VTECKEDQFRCKNKAYCIPVRWLCDGIHDCVDGSDEEDCVQGCVLIGIVFCAIKETIKFP 2756
Query: 612 ATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFC 466
C+N CL+P+ N C N+ E+ C
Sbjct: 2757 CPPTRPYRCRNNRVCLRPEQICNEVDD------------CGDNSDEDHC 2793
Score = 244 bits (623), Expect = 2e-62
Identities = 215/761 (28%), Positives = 312/761 (40%), Gaps = 38/761 (4%)
Frame = -1
Query: 4011 PPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCG 3832
PP C A QF C +C++ CDG DC G DE C N C E QFKC
Sbjct: 2 PPQLCKAEQFQCNNK------RCIHDRWRCDGDDDCLDGSDEHADICFNHSCPENQFKC- 54
Query: 3831 DKKKCIPLTSVCDKEKDCDDGSDELN--CEITSCKPDFFACFNGTAISKCIPKEFYCDGE 3658
+CIP +CD DC + DE N C +C+ D F+C NG +CIP + CD E
Sbjct: 55 QNNRCIPKRWLCDGANDCGNNEDESNKTCAARTCQFDQFSCGNG----RCIPTSWLCDRE 110
Query: 3657 DDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQCDGTLDCRDGSDEKGCKKECA-- 3484
DDC + DE SC QF C +G+CI + CD DC DGSDE GC C+
Sbjct: 111 DDCGDQTDEMTSCEFPTCEPLTQFICKNGRCISSKWLCDSDDDCGDGSDELGCIHSCSAD 170
Query: 3483 -IVCDNS-CVHADDLCDGKKKCNDGSDEDEEACVIKQLLEKENRKCGG------------ 3346
C N C+ + CDG C D SDE C ++ +C G
Sbjct: 171 QFRCYNGRCIPSHWACDGDNDCGDYSDETRTNCTKEET--PAPGRCNGKEFQCSPDGNCV 228
Query: 3345 ---FACDGIVDCEDGSDEKGCPDLECHLASNKSLICDGTIDCSSGKDENNCHNNGESNFF 3175
+ CDG DCEDGSDEKG C+GT+ K + +C + G
Sbjct: 229 PELWRCDGEKDCEDGSDEKG---------------CNGTLRLCDEKTKFSCVSTGRC--- 270
Query: 3174 QCSMQTIKEWQVCDGRWDCADGLDESP---EMCASRKARCFRIGYCDDKKQCLDVSTALC 3004
K W +CDG DC D DE MC K C +D CL LC
Sbjct: 271 -----ISKAW-LCDGDIDCEDQSDEDNCEGYMCGPPKYPC-----ANDTSICLQPEK-LC 318
Query: 3003 DGIRDCFDGSDENPIHCKDMCKGKYRCTNGRCIDVSARXXXXXXXXXXXXXXXXGAE--- 2833
+G RDC DGSDE + C + C++ + R E
Sbjct: 319 NGRRDCPDGSDEGDL-CDECSLNNGGCSHQCSVVPGGRIVCSCPSGFNLSVDNKTCEIMD 377
Query: 2832 -CHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSL 2656
C C+Q C N+ +C C G+ +K+ EN A + + + + + L
Sbjct: 378 YCTKHLKCSQVCEQHKNNV-KCSCYEGWKLSKDGENCISTDPFEAFIIFSIRHEIRKIDL 436
Query: 2655 ENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSW 2476
S+L P N I +DF F +L+Y + ++ R K G + +
Sbjct: 437 HKRDYSLLVPGLR---NTI--ALDFH---FSQSLLYWTDVVEDKI-YRGKLSDTGGVSAI 487
Query: 2475 G----EEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNS 2308
+T +T D++ N+Y+ +S+ I VAK T TLI +
Sbjct: 488 EVIVQHGLATPEGLTVDWIAGNIYWIDSNLDQ----------IEVAKLDGTLRTTLIAGA 537
Query: 2307 TGTINSLAVDPIKRLIFWTT-SAPVPRILSANLDG---KPIAQPFKTGSQPHKALVERNI 2140
++A+DP ++FWT A PRI SA++ G K I + TG+ P+
Sbjct: 538 MEHPRAIALDPRYGILFWTDWDANFPRIESASMSGAERKIIYKDMDTGAWPN-------- 589
Query: 2139 FEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDR-RTVRKFELGDTPVTMDVLGGYIYL 1963
+ +D +R+ W D I + +DG +R E P + + G +Y
Sbjct: 590 ----GLTVDHFEKRIVWTDARSDAIYSALYDGTGMIEIIRGHEYLSHPFAVSLYGSEVYW 645
Query: 1962 IT-RQGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAK 1843
R ++ + +K+TG+ +QK + +++ HP++
Sbjct: 646 TDWRTNTLAKANKWTGQNVSVIQKTS--AQPFDLQIYHPSR 684
Score = 182 bits (461), Expect = 1e-43
Identities = 115/355 (32%), Positives = 161/355 (44%), Gaps = 22/355 (6%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC---TCNENEFRCQ 6403
D D C + C P F C N CIP+ C+ NDC + +DE NC TC +F C
Sbjct: 2532 DGSDEANCDKKTCGPHEFQCKNNNCIPDHWRCDSQNDCGDNSDEENCKPQTCTLKDFLCA 2591
Query: 6402 SGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDG 6223
+G C+ ++ C+ DC D SDE C CS ++F + QCI W+CDG
Sbjct: 2592 NGDCVSARFWCDGDYDCADGSDERYCE-TGCSR-DQFQ-------CSNGQCISAKWRCDG 2642
Query: 6222 TNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADG 6043
DC G DEK+C A +C +++ C A+ C+ +C+G+ DCADG
Sbjct: 2643 HEDCKLGDDEKNC----------EPASPTCSV-SEYIC-ASGGCISASLKCNGEYDCADG 2690
Query: 6042 SDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKG------ 5881
SDE +C +C +F C++ CIP+ CDG DC DG DE C C G
Sbjct: 2691 SDEMDC-VTECKEDQFRCKNKAYCIPVRWLCDGIHDCVDGSDEEDCVQGCVLIGIVFCAI 2749
Query: 5880 ---------GNATFRCTNHR-CIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPS 5731
+RC N+R C+ C+ DDC DN+ D++ A R
Sbjct: 2750 KETIKFPCPPTRPYRCRNNRVCLRPEQICNEVDDCGDNSDEDHCDKITYKA-RPCKKDEF 2808
Query: 5730 RCADETCVVACELTAVLCDGIQDCSDGFDEKNC--ASLDRQCKPNEWMC-DSGQC 5575
C D+ C+ + CD DC DG DE++C + + C+ N C D C
Sbjct: 2809 TCNDKKCIP----MELQCDWFDDCGDGSDEQDCKISVTEYTCEDNVNPCGDDAYC 2859
Score = 137 bits (345), Expect = 4e-30
Identities = 94/299 (31%), Positives = 147/299 (48%), Gaps = 7/299 (2%)
Frame = -1
Query: 5016 LSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKG---IDGI 4846
+S + V +D+ +D +YWTD+ NK S S + T++ + T G ++GI
Sbjct: 969 VSGTSFAVGIDFHAGNDTIYWTDMGF--NKI---SRSKRDQTWK--EDVVTNGLGRVEGI 1021
Query: 4845 AVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGA 4666
AVDW+ NIY+TD + I V + G F +++ L+ PR+I + P + +FWT+WG
Sbjct: 1022 AVDWIAGNIYWTDHGFNLIEVARLNGSFRYVIIS-QGLDQPRSIAVHPEKGYLFWTEWGQ 1080
Query: 4665 SAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYD-GSKRR 4489
IG+ +DGS E+V+L I WPN +++D +LY+ DA D I + + G R
Sbjct: 1081 IPCIGKAYLDGS-EKVVLVSLGIVWPNGISIDYEENKLYWCDARTDKIERIDLESGGNRE 1139
Query: 4488 MVLRGSVRHIFALAVFEDYVYWSD--WHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIV 4315
+VL GS +F++AVF Y+YWSD N +I R HK T+ + +G +
Sbjct: 1140 IVLSGSNVDMFSVAVFGAYIYWSDRAHANGSIRRGHKNEATDAVTM-----RTGLGINLK 1194
Query: 4314 HPSLQSMGSLKTARHPCSQPARCDNLCIPANTPDLTTSSDNFTCMCAQGFRSE-GRSCV 4141
+ + K C LC L TC CA G+ +E G +C+
Sbjct: 1195 EVKVFNRAREKGTNVCAKNNGGCHQLC-------LYRGKAQRTCACAHGYLAEDGITCL 1246
Score = 111 bits (278), Expect = 2e-22
Identities = 84/301 (27%), Positives = 117/301 (37%), Gaps = 40/301 (13%)
Frame = -1
Query: 4134 CKP-NDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQN 3958
C+P F+C K +CISS W + C A QF C
Sbjct: 128 CEPLTQFIC-KNGRCISSKWLCDSDDDCGDGSDELGCIHS------CSADQFRC------ 174
Query: 3957 ATAQCLYASKLCDGVKDCSGGDDEEPAFCENFE------CTEAQFKCGDKKKCIPLTSVC 3796
+C+ + CDG DC DE C E C +F+C C+P C
Sbjct: 175 YNGRCIPSHWACDGDNDCGDYSDETRTNCTKEETPAPGRCNGKEFQCSPDGNCVPELWRC 234
Query: 3795 DKEKDCDDGSDELNCEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCF 3616
D EKDC+DGSDE C T D F+ + +CI K + CDG+ DC E Q + D+C
Sbjct: 235 DGEKDCEDGSDEKGCNGTLRLCDEKTKFSCVSTGRCISKAWLCDGDIDC-EDQSDEDNCE 293
Query: 3615 GIGECTHEQFQCTSGK--CIPKRRQCDGTLDCRDGSDE-----------KGCKKECAIV- 3478
G C ++ C + C+ + C+G DC DGSDE GC +C++V
Sbjct: 294 GY-MCGPPKYPCANDTSICLQPEKLCNGRRDCPDGSDEGDLCDECSLNNGGCSHQCSVVP 352
Query: 3477 ---------------CDNSCVHADDLCDGKKKCNDGSDEDEE----ACVIKQLLEKENRK 3355
DN D C KC+ ++ + +C L K+
Sbjct: 353 GGRIVCSCPSGFNLSVDNKTCEIMDYCTKHLKCSQVCEQHKNNVKCSCYEGWKLSKDGEN 412
Query: 3354 C 3352
C
Sbjct: 413 C 413
Score = 102 bits (254), Expect = 1e-19
Identities = 53/151 (35%), Positives = 74/151 (48%), Gaps = 2/151 (1%)
Frame = -1
Query: 828 CDDYCTNNSKCTITNGTHFECDCKPGFKGLRCEQETKCSECSNEAKCIKKPSGTVICQCP 649
C YC N+ CTI++ EC C F+G +CE + KC C I K + ++C C
Sbjct: 3459 CHHYCVNSESCTISDDGSVECVCPVRFEGPKCEVD-KCIRCHGGHCIINKDTNDIVCNCT 3517
Query: 648 QGLGGEYCEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSS--NACE 475
G C+ C NGG C + DP N P CLCS GFK C N C+
Sbjct: 3518 NGKIASTCQLCDGY------CYNGGTC-QLDPDTN--VPVCLCSVGFKSQRCDQKVNPCD 3568
Query: 474 NFCLHDGNCTLDEYFEPQCECYQAFIGDRCQ 382
+C ++G CTL + EP+C+C + G +C+
Sbjct: 3569 YYCQNEGICTLTAFNEPRCKCSANWSGTQCE 3599
Score = 94.4 bits (233), Expect = 3e-17
Identities = 103/395 (26%), Positives = 144/395 (36%), Gaps = 70/395 (17%)
Frame = -1
Query: 6051 ADGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCP-DGE----DEHQCETECDS 5887
A +D +C+ C C P DGR +C G+ D+++C T+ +
Sbjct: 1518 AVANDTNSCELSPCAQMNGGCHDLCLLTP-----DGRVNCSCRGDRILIDDNRCVTKNST 1572
Query: 5886 KGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSL-------------------------- 5785
+ F C N CI CDGT C D +
Sbjct: 1573 CNIYSEFECGNGECIDYQLTCDGTAHCKDKSDEKLFYCENRGCRKGFKPCSNRRCISRNK 1632
Query: 5784 ----------GSDEVDC---AAGRTSFHVPSRCADETCVVACELTAVLCDGIQDCSDGFD 5644
SDE+DC A T F RCAD TC+ + C+ I DC+D D
Sbjct: 1633 VCDGRNDCGDNSDEIDCKDSACTSTEF----RCADGTCIG----KSAQCNQIIDCADASD 1684
Query: 5643 EKNCASLD------RQCKPNEWM-CDS-GQCIDSGRLCDASVDCVDGSDEW---VEICSL 5497
EKNC + + K ++ C+S CI +CD S DC D +DE V+
Sbjct: 1685 EKNCNNTNCAYFYKLGIKSTGFISCNSTSLCILPEWICDGSNDCGDYTDELKCPVQNKPT 1744
Query: 5496 SEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDE-QCDNPQGNCSSTRNSC- 5323
E GCPSG C+ LCDG++DC G+DE CD+ +CS + +C
Sbjct: 1745 CEENYFGCPSG----------RCILNTWLCDGQKDCEDGVDELHCDS---SCSWNQFACS 1791
Query: 5322 -----DQTWNCQRH----AGFESCSCDDGYHLSPYDKKTCLRSPSCPK----ANCSHFCI 5182
+ W C G + G +CL S +C + C
Sbjct: 1792 ADKCISKQWTCDGEDDCGNGLDESDAICGSVTCAVGTFSCLGSHACVPHHWLCDGERDCP 1851
Query: 5181 DRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEIL 5077
+ D CAP EN CR N I + +
Sbjct: 1852 NGSDELSTAGCAPNNTCDENAFMCRNNICIPKQFV 1886
Score = 88.6 bits (218), Expect = 2e-15
Identities = 61/255 (23%), Positives = 118/255 (45%), Gaps = 10/255 (3%)
Frame = -1
Query: 5091 EAEILMVYGHRLKLFTID------GHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGN 4930
E + ++Y R ++ +D A + ++ + +D+D + +YWTDV
Sbjct: 688 ERKKFLLYARRSEIRGVDIDNPYFNFITAFTVPDIDDVTVIDFDAVEERLYWTDVKTQTI 747
Query: 4929 KAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHD--AIAVCDMRGRFNR 4756
K + + I S + I G+AVDW+ RN+Y+ D I V + G
Sbjct: 748 KRAFINGTG----LETIISRDIQSIRGLAVDWISRNLYWISSEFDETQINVAHLDGSLKT 803
Query: 4755 ILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALA 4576
++ G ++ P+ + + P++ ++WTD I NMDGSN +++ Q++ + P L+
Sbjct: 804 SIIHG--IDKPQCLAVHPVKGKLYWTDGNT---INMANMDGSNSKILFQNQ--KDPVGLS 856
Query: 4575 VDAPAQRLYFGDAHRDYIASCNYDGSKRRMV--LRGSVRHIFALAVFEDYVYWSDWHNHT 4402
+D +LY+ + I CN DG ++ ++ + AL + + ++W+D +
Sbjct: 857 IDYVENKLYWISSGNGTINRCNLDGGNLEIIDSMKEDLPKATALTIMDKKLWWADQNLAQ 916
Query: 4401 IERVHKITGTNRKVL 4357
I +K G N +L
Sbjct: 917 IGTCNKRDGRNPTIL 931
Score = 79.0 bits (193), Expect = 1e-12
Identities = 51/161 (31%), Positives = 65/161 (39%), Gaps = 2/161 (1%)
Frame = -1
Query: 1176 HECLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPITC 997
H C+N C+ ++ C+CP F G CE C G C I K + I C
Sbjct: 3461 HYCVNSESCTISDDGSV--ECVCPVRFEGPKCEVDKCIRC--HGGHCI--INKDTNDIVC 3514
Query: 996 SCEQNAAAHNTDCSPICQKQPNWCHNGGRC-LDTPGYPGKCKCLPRFAGPRCDVPVQ-CD 823
+C A CQ +C+NGG C LD C C F RCD V CD
Sbjct: 3515 NCTNGKIAST------CQLCDGYCYNGGTCQLDPDTNVPVCLCSVGFKSQRCDQKVNPCD 3568
Query: 822 DYCTNNSKCTITNGTHFECDCKPGFKGLRCEQETKCSECSN 700
YC N CT+T C C + G +CE+ S S+
Sbjct: 3569 YYCQNEGICTLTAFNEPRCKCSANWSGTQCERPAPKSSKSD 3609
Score = 67.8 bits (164), Expect = 3e-09
Identities = 40/154 (25%), Positives = 68/154 (43%), Gaps = 4/154 (2%)
Frame = -1
Query: 1638 YFCYNNAGCSPQKT----CVCPPGFYGRQCEINECSETCWNGETCAVQEFGSTTNVVCHC 1471
++C N+ C+ CVCP F G +CE+++C +G C + + T ++VC+C
Sbjct: 3461 HYCVNSESCTISDDGSVECVCPVRFEGPKCEVDKCIRC--HGGHCIINK--DTNDIVCNC 3516
Query: 1470 PSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHKADAK 1291
+ S+C +C+G C G+C+ P + C C G+ C K +
Sbjct: 3517 TNGKIASTC--QLCDGYCYNGGTCQLDP-------DTNVPVCLCSVGFKSQRCDQKVNP- 3566
Query: 1290 VCYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQ 1189
C +C + G C RC C +G +C+
Sbjct: 3567 -CDYYCQNEGICTLTAFNEPRCKCSANWSGTQCE 3599
Score = 67.4 bits (163), Expect = 4e-09
Identities = 46/165 (27%), Positives = 64/165 (37%), Gaps = 4/165 (2%)
Frame = -1
Query: 1560 EINECSETCWNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCP 1381
+I C C N E+C + + GS V C CP + C + C G G C
Sbjct: 3455 DIYVCHHYCVNSESCTISDDGS---VECVCPVRFEGPKCEVDKCIRCHG--GHCIINKDT 3509
Query: 1380 KDEPHCRSYSFCECDKGWTGPHCRHKADAKVCYGHCFSGGACDGEGPLNLR-CSCGDGLT 1204
D C C G C ++C G+C++GG C + N+ C C G
Sbjct: 3510 ND-------IVCNCTNGKIASTC------QLCDGYCYNGGTCQLDPDTNVPVCLCSVGFK 3556
Query: 1203 GNRCQ---NCVGHECLNGGFCSYANSNRSLPHCICPSGFTGDHCE 1078
RC N + C N G C+ N P C C + ++G CE
Sbjct: 3557 SQRCDQKVNPCDYYCQNEGICTLTAFNE--PRCKCSANWSGTQCE 3599
Score = 62.4 bits (150), Expect = 1e-07
Identities = 67/252 (26%), Positives = 98/252 (38%), Gaps = 10/252 (3%)
Frame = -1
Query: 2652 NSQVSVLRPVFNIKMNLIPGGIDF--GYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGS 2479
N ++ L PV + GIDF G D +Y +G +++ RSK+ +
Sbjct: 960 NDKMEALMPVSGTSFAV---GIDFHAGNDT-----IYWTDMGFNKIS-RSKRDQ-----T 1005
Query: 2478 WGEEESTAGL-----ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIV 2314
W E+ T GL I D++ N+Y+T+ I VA+ + +I
Sbjct: 1006 WKEDVVTNGLGRVEGIAVDWIAGNIYWTDHGFNL----------IEVARLNGSFRYVIIS 1055
Query: 2313 NSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFE 2134
S+AV P K +FWT +P I A LDG LV I
Sbjct: 1056 QGLDQPRSIAVHPEKGYLFWTEWGQIPCIGKAYLDG-----------SEKVVLVSLGIVW 1104
Query: 2133 PTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITR 1954
P + +D+ +LYW D IE + + R + ++ V G YIY R
Sbjct: 1105 PNGISIDYEENKLYWCDARTDKIERIDLESGGNREIVLSGSNVDMFSVAVFGAYIYWSDR 1164
Query: 1953 ---QGSIHRMHK 1927
GSI R HK
Sbjct: 1165 AHANGSIRRGHK 1176
Score = 57.4 bits (137), Expect = 5e-06
Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 3/93 (3%)
Frame = -1
Query: 717 CSECSNEAKCIKKPSGTVICQCPQG---LGGEYCEKITATSCHQLECKNGGYCLKPDPSA 547
C + + E C+ PSG C CP+G + G ++ +L C+NGG C+ +
Sbjct: 3217 CLDLTCEFICLLNPSGAS-CACPEGKSLVNGTCVDQSLLDDTCKLTCENGGKCIINE--- 3272
Query: 546 NRTSPTCLCSPGFKGLLCSSNACENFCLHDGNC 448
+ P C C P + G C +N C N+C + G C
Sbjct: 3273 -KGDPRCHCWPSYSGERCETNHCYNYCQNGGTC 3304
Score = 53.1 bits (126), Expect = 9e-05
Identities = 35/140 (25%), Positives = 48/140 (34%), Gaps = 35/140 (25%)
Frame = -1
Query: 933 NWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPV-------------------------- 832
++C N C + +C C RF GP+C+V
Sbjct: 3461 HYCVNSESCTISDDGSVECVCPVRFEGPKCEVDKCIRCHGGHCIINKDTNDIVCNCTNGK 3520
Query: 831 ------QCDDYCTNNSKCTITNGTHFE-CDCKPGFKGLRCEQETKCSE--CSNEAKCIKK 679
CD YC N C + T+ C C GFK RC+Q+ + C NE C
Sbjct: 3521 IASTCQLCDGYCYNGGTCQLDPDTNVPVCLCSVGFKSQRCDQKVNPCDYYCQNEGICTLT 3580
Query: 678 PSGTVICQCPQGLGGEYCEK 619
C+C G CE+
Sbjct: 3581 AFNEPRCKCSANWSGTQCER 3600
Score = 53.1 bits (126), Expect = 9e-05
Identities = 39/160 (24%), Positives = 60/160 (37%)
Frame = -1
Query: 1314 CRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQNCVGHECLNGGFCSYANS 1135
C D VC+ +C + +C ++ C C G +C+ C +GG C N
Sbjct: 3450 CNILLDIYVCHHYCVNSESCTISDDGSVECVCPVRFEGPKCEVDKCIRC-HGGHC-IINK 3507
Query: 1134 NRSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCSCEQNAAAHNTDCS 955
+ + C C +G C+ LC C G C D + CS + C
Sbjct: 3508 DTNDIVCNCTNGKIASTCQ--LCDGYCYNGGTCQLDPDTNVPVCLCS----VGFKSQRCD 3561
Query: 954 PICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVP 835
+C N G C T +CKC ++G +C+ P
Sbjct: 3562 QKVNPCDYYCQNEGICTLTAFNEPRCKCSANWSGTQCERP 3601
Score = 48.5 bits (114), Expect = 0.002
Identities = 60/307 (19%), Positives = 118/307 (37%), Gaps = 38/307 (12%)
Frame = -1
Query: 5124 NQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLTNGVALDYDVKSDLVYWTDV 4945
++ C ++ ++ G+ + + +DG L N + V L D + +YW
Sbjct: 810 DKPQCLAVHPVKGKLYWTDGNTINMANMDGSNSKILFQNQKDPVGLSIDYVENKLYWIS- 868
Query: 4944 AHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGR 4765
GN I + +I+S+ A+ + + +++ D+N I C+ R
Sbjct: 869 --SGN-GTINRCNLDGGNLEIIDSMKEDLPKATALTIMDKKLWWADQNLAQIGTCNKRDG 925
Query: 4764 FNRILLKG-------------TPLNDPRAIVLDP---LQAL------------------- 4690
N +L+ R I LDP ++AL
Sbjct: 926 RNPTILRNKTSGVVHMKVYDKAAQQGIRGISLDPNDKMEALMPVSGTSFAVGIDFHAGND 985
Query: 4689 -VFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASC 4513
++WTD G + I R D + ++ ++ + R +AVD A +Y+ D + I
Sbjct: 986 TIYWTDMGFN-KISRSKRDQTWKEDVVTNGLGR-VEGIAVDWIAGNIYWTDHGFNLIEVA 1043
Query: 4512 NYDGSKRRMVLRGSVRHIFALAVFED--YVYWSDWHNHTIERVHKITGTNRKVLIQDKQY 4339
+GS R +++ + ++AV + Y++W++W + G+ + VL+
Sbjct: 1044 RLNGSFRYVIISQGLDQPRSIAVHPEKGYLFWTEWGQIPCIGKAYLDGSEKVVLVSLGIV 1103
Query: 4338 RPMGFKI 4318
P G I
Sbjct: 1104 WPNGISI 1110
Score = 47.0 bits (110), Expect = 0.006
Identities = 104/452 (23%), Positives = 150/452 (33%), Gaps = 39/452 (8%)
Frame = -1
Query: 1791 CPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGC 1612
C + C+ D++ + C P F+ +C+ R A+ CG+ +N C
Sbjct: 25 CDGDDDCLDGSDEHADICFNHSC-PENQFKCQNNRCIPKRWLCDGANDCGNNEDESNKTC 83
Query: 1611 SPQKTCVCPPGFYGRQCEINECSETCWNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNV 1432
+ +TC F C C T W + + G T+ + +SC
Sbjct: 84 AA-RTCQ----FDQFSCGNGRCIPTSWLCDR--EDDCGDQTDEM---------TSCEFPT 127
Query: 1431 CEGVCGPRGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHK--ADAKVCY-GHCF-SG 1264
CE + + CK C + C S +C G C H AD CY G C S
Sbjct: 128 CEPLT--QFICKNGRCISSKWLCDSDD--DCGDGSDELGCIHSCSADQFRCYNGRCIPSH 183
Query: 1263 GACDGEGPLNLRCSCGDGLTGNRCQNCVGHECLNGGFCSYANSNRSLPHCICPSGFTGD- 1087
ACDG+ CGD R NC E G C+ S P + D
Sbjct: 184 WACDGDN------DCGDYSDETRT-NCTKEETPAPGRCNGKEFQCSPDGNCVPELWRCDG 236
Query: 1086 --HCEEYLCKDACPFGSKCTYDITKPMDPITCSCEQNAAAHNTDCSPICQKQPNWCHNGG 913
CE+ + C + + TK T C A + D C+ Q + + G
Sbjct: 237 EKDCEDGSDEKGCNGTLRLCDEKTKFSCVSTGRCISKAWLCDGDID--CEDQSDEDNCEG 294
Query: 912 RCLDTPGYP-----GKCKCLPRFAGPRCDVPVQCD--DYCTNNSKCTITNGTHFECDCKP 754
P YP C + R D P D D C +C++ NG
Sbjct: 295 YMCGPPKYPCANDTSICLQPEKLCNGRRDCPDGSDEGDLC---DECSLNNGG-------- 343
Query: 753 GFKGLRCEQETKCSECSNEAKCIKKPSGTVICQCPQGLG----------GEYCEKITATS 604
CS++ C P G ++C CP G +YC K S
Sbjct: 344 ---------------CSHQ--CSVVPGGRIVCSCPSGFNLSVDNKTCEIMDYCTKHLKCS 386
Query: 603 --CHQ----LEC---------KNGGYCLKPDP 553
C Q ++C K+G C+ DP
Sbjct: 387 QVCEQHKNNVKCSCYEGWKLSKDGENCISTDP 418
Score = 44.7 bits (104), Expect = 0.031
Identities = 35/135 (25%), Positives = 59/135 (42%)
Frame = -1
Query: 2448 ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIK 2269
+ D++ N+Y+ S FD + I VA D S +T I++ LAV P+K
Sbjct: 771 LAVDWISRNLYWISSE-------FD-ETQINVAHL-DGSLKTSIIHGIDKPQCLAVHPVK 821
Query: 2268 RLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYW 2089
++WT + AN+DG + ++ +N +P + +D+ +LYW
Sbjct: 822 GKLYWTDGNTINM---ANMDGS------------NSKILFQNQKDPVGLSIDYVENKLYW 866
Query: 2088 IDVLKRTIETVSFDG 2044
I TI + DG
Sbjct: 867 ISSGNGTINRCNLDG 881
Score = 41.2 bits (95), Expect = 0.34
Identities = 44/195 (22%), Positives = 82/195 (41%), Gaps = 2/195 (1%)
Frame = -1
Query: 2451 LITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPI 2272
+I +D + +Y+T+ Q I A T T+I +I LAVD I
Sbjct: 727 VIDFDAVEERLYWTDVKTQT----------IKRAFINGTGLETIISRDIQSIRGLAVDWI 776
Query: 2271 KRLIFWTTSA-PVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERL 2095
R ++W +S +I A+LDG K + I +P + + +L
Sbjct: 777 SRNLYWISSEFDETQINVAHLDGS------------LKTSIIHGIDKPQCLAVHPVKGKL 824
Query: 2094 YWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITR-QGSIHRMHKFTG 1918
YW D TI + DG + + + + + +++D + +Y I+ G+I+R + G
Sbjct: 825 YWTD--GNTINMANMDGSNSKILFQNQKDPVGLSIDYVENKLYWISSGNGTINRCN-LDG 881
Query: 1917 KTNKYVQKIREVSPR 1873
+ + ++E P+
Sbjct: 882 GNLEIIDSMKEDLPK 896
Score = 40.0 bits (92), Expect = 0.77
Identities = 60/264 (22%), Positives = 91/264 (33%), Gaps = 36/264 (13%)
Frame = -1
Query: 1641 DYFCYNNAGCSPQKTCV----CPPGFYGRQCEINECSET---CWNGETCAVQEFGSTTNV 1483
+Y C + S C C G C + EC E C N C + +
Sbjct: 2666 EYICASGGCISASLKCNGEYDCADGSDEMDC-VTECKEDQFRCKNKAYCIPVRW--LCDG 2722
Query: 1482 VCHCPSNYTQSSCATN-VCEGV--CGPRGSCKTVPCPKDEPH-CRSYSFC---------- 1345
+ C + C V G+ C + + K PCP P+ CR+ C
Sbjct: 2723 IHDCVDGSDEEDCVQGCVLIGIVFCAIKETIK-FPCPPTRPYRCRNNRVCLRPEQICNEV 2781
Query: 1344 -ECDKGWTGPHC-RHKADAKVCYGHCFSGGACDGEG--PLNLRCS----CGDGLTGNRCQ 1189
+C HC + A+ C F+ C+ + P+ L+C CGDG C+
Sbjct: 2782 DDCGDNSDEDHCDKITYKARPCKKDEFT---CNDKKCIPMELQCDWFDDCGDGSDEQDCK 2838
Query: 1188 NCVG-HECLNG----GFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDA--CPFGSKCTY 1030
V + C + G +Y N ++ C C GF + C+D C C+
Sbjct: 2839 ISVTEYTCEDNVNPCGDDAYCNQTKTSLLCQCKPGFQRNEMNRQ-CEDINECMVFGACSQ 2897
Query: 1029 DITKPMDPITCSCEQNAAAHNTDC 958
C+CE+N N C
Sbjct: 2898 HCNNVKGSYRCACEKNYKEWNNSC 2921
Score = 38.1 bits (87), Expect = 2.9
Identities = 17/63 (26%), Positives = 33/63 (51%), Gaps = 8/63 (12%)
Frame = -1
Query: 546 NRTSPTCLCSPGFKGLLCSS--------NACENFCLHDGNCTLDEYFEPQCECYQAFIGD 391
N + +C C G K L+ + + C+ C + G C ++E +P+C C+ ++ G+
Sbjct: 3229 NPSGASCACPEG-KSLVNGTCVDQSLLDDTCKLTCENGGKCIINEKGDPRCHCWPSYSGE 3287
Query: 390 RCQ 382
RC+
Sbjct: 3288 RCE 3290
Score = 36.6 bits (83), Expect = 8.5
Identities = 34/134 (25%), Positives = 44/134 (32%), Gaps = 4/134 (2%)
Frame = -1
Query: 1077 EYLCKDACPFGSKCTYDITKPMD-PITC---SCEQNAAAHNTDCSPICQKQPNWCHNGGR 910
EYL D S + K MD P C +CE + + S C + + + G
Sbjct: 3190 EYLSVDVDKAKSALIFHRYKQMDLPNPCLDLTCEFICLLNPSGASCACPEGKSLVN--GT 3247
Query: 909 CLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSKCTITNGTHFECDCKPGFKGLRCE 730
C+D CK C N KC I C C P + G RCE
Sbjct: 3248 CVDQSLLDDTCKLT-----------------CENGGKCIINEKGDPRCHCWPSYSGERCE 3290
Query: 729 QETKCSECSNEAKC 688
+ C N C
Sbjct: 3291 TNHCYNYCQNGGTC 3304
>gi|34853954|ref|XP_231214.2| similar to low density lipoprotein
receptor related protein LRP1B/LRP-DIT [Rattus
norvegicus]
Length = 2281
Score = 696 bits (1795), Expect = 0.0
Identities = 585/2044 (28%), Positives = 823/2044 (39%), Gaps = 213/2044 (10%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC---TCNENEFRCQS 6400
DE YC R CR G+ C N C+P K+C+ NDC + +DE +C TC+ EFRC
Sbjct: 296 DEKLLYCENRSCRSGFKPCYNRRCVPHGKLCDGTNDCGDGSDELDCKVSTCSTVEFRCTD 355
Query: 6399 GACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGM--TGLINCATTSQCIHPSWKCD 6226
G CIP ARCN DC+DASDE GC +C+ + G+ TG I C +TS C+ PSW CD
Sbjct: 356 GTCIPRSARCNQNMDCSDASDEKGCNNTDCTHFYKLGVKSTGFIRCNSTSLCVLPSWICD 415
Query: 6225 GTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCAD 6046
G+NDC D SDE C V C+ + F C + R C+ W CDGQ DC D
Sbjct: 416 GSNDCGDYSDELKC---------PVQNKHKCE-ENYFGCPSGR-CILNTWVCDGQKDCED 464
Query: 6045 GSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNAT- 5869
G DE +CD+ C+ +F+C S KCI CDG DC DG DE D+ G T
Sbjct: 465 GLDELHCDSS-CSWNQFAC-SVHKCISKHWICDGEDDCGDGLDES------DNICGAVTC 516
Query: 5868 ----FRC-TNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVV 5704
F C ++H C+P W CDG DC D + L S CA T C ++ C+
Sbjct: 517 AADMFSCQSSHACVPQHWLCDGERDCPDGSDELSS--AGCAPNNTCDENAFMCHNKVCIP 574
Query: 5703 ACELTAVLCDGIQDCSDGFDE-----KNCASLDR----------------------QCKP 5605
+CD DC DG DE +C+ DR QC P
Sbjct: 575 K----QFVCDHDDDCGDGSDEFLECGTSCSCRDRLQTGCYGSLTSTVQYDKFFRYRQCGP 630
Query: 5604 NEWMCDSGQC-IDSGRLCDASVDCVDGSDEWVEICSLSEPPRRGCPSGWSCLLTNGTIGC 5428
E+ C G+C +++ CD DC D SDE I C S + + NG C
Sbjct: 631 EEFRCADGRCLVNTLWQCDGDFDCPDSSDE-APINPRCTSAEHSCNSSFF-MCKNGR--C 686
Query: 5427 LQEQQLCDGRRDCMSGIDEQCDNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSP 5248
+ LCD R DC G +E + S + C Q +CQ C C G+ L
Sbjct: 687 IPRDGLCDNRDDCGDGSEEPKCHINECLSKKISGCSQ--DCQDLPISYKCKCWPGFQLKD 744
Query: 5247 YDKKTCLRSPSCPKA-NCSHFCIDRRDVGHQCFCAPGYILS-ENQKDCRRNDTIEAEILM 5074
D KTC+ C CS CI+ ++C C GY +NQ CR+ ++++
Sbjct: 745 -DGKTCVDIDECSTGFPCSQQCINTYGT-YKCRCTEGYETQPDNQNGCRK----PSKVID 798
Query: 5073 VYGH--RLKLFTIDGHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQ 4900
V+ LK +A L N +A+D+D + + +YW D S++
Sbjct: 799 VFQEAVELKANPCLNIREAASRHGLNNVIAIDFDYREEFIYWID-------------SSR 845
Query: 4899 PNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPR 4720
PN R IN + G D I V W R D + V GR
Sbjct: 846 PNGSR-INRMCLNGSD-IKVWW---------RRGDELGV----GRN-------------- 876
Query: 4719 AIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGD 4540
++W D HIGR+ MDG+N+ V+++ + R P AL +D RLY+ D
Sbjct: 877 ----------LYWIDCCEYPHIGRVGMDGTNQSVVIETKISR-PMALTIDYVNHRLYWAD 925
Query: 4539 AHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKV 4360
++I N DGS R V + + AL +FEDY+YW+D ++ RVHK +G +R
Sbjct: 926 --ENHIEFSNMDGSHRHKVPNQDIPGVIALTLFEDYIYWTDGKTKSLSRVHKTSGADRLS 983
Query: 4359 LIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDNLCIPANTPDLTTSSDNFTCM 4180
LI + ++ H Q G KT TC
Sbjct: 984 LIYS-WHAITDIQVYHSYRQPDGPGKT-----------------------------HTCA 1013
Query: 4179 CAQGF--RSEGRSCVSECKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPP 4006
C F ++ R+C+S C + F C KT KCI WW+ CP
Sbjct: 1014 CPTNFYLAADNRTCLSNCTASQFRC-KTDKCIPFWWKCDTVDDCGDGSDE----PDDCPE 1068
Query: 4005 FPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSG------------------------ 3898
F C G+F CG T C + +CDG DC
Sbjct: 1069 FKCQPGRFQCG------TGLCALPAFICDGENDCGDNSDELNCGQFKCTKNKKCIPVNLR 1122
Query: 3897 -------GDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITS 3739
GD+E+ C C+ F+C K CI VCD++ DC D SDE NC+ +
Sbjct: 1123 CNGQDDCGDEEDERDCPENSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEANCDKKT 1182
Query: 3738 CKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIP 3559
C P F C N + CIP + CD ++DC + DE ++C CT F C++G C+
Sbjct: 1183 CGPHEFQCKN----NNCIPDHWRCDSQNDCSDNSDE-ENCKP-QTCTLRDFLCSNGDCVS 1236
Query: 3558 KRRQCDGTLDCRDGSDEKG----CKKECAIVC--------DNSCVHADDLCDGKKKCNDG 3415
R CDG DC DGSDE G KK C C + C+ A CDG + C G
Sbjct: 1237 SRFWCDGEFDCADGSDEVGISVNAKKNCETSCSKDQFQCSNGQCLSAKWKCDGHEDCKYG 1296
Query: 3414 SDEDEEACVIKQLLEKENRKCGG------FACDGIVDCEDGSDEKGCPDLECH----LAS 3265
DE E G C+G DC DGSDE C EC
Sbjct: 1297 EDEKNCEPAFPVCSSSEYMCASGGCLSASLKCNGETDCVDGSDEMDCVT-ECKEDQFQCR 1355
Query: 3264 NKSL------ICDGTIDCSSGKDENNCHNNGE---SNFFQCSMQTIK-EWQVCDGRWDCA 3115
NK+ +CDG DC G DE NC G ++ F C+ K + VCDG DC
Sbjct: 1356 NKAYCIPIRWLCDGIYDCVDGSDEENCGRGGSICRADEFLCNNSLCKLHFWVCDGEDDCG 1415
Query: 3114 DGLDESPEMCA------SRKARCFRIGYC----------------DDKKQCLDVST---- 3013
D DE P+MC +R RC C D++ C +
Sbjct: 1416 DNSDEVPDMCVKFLCPPTRPYRCRNDRICLQLEKMCNGINDCGDNSDEEHCSGTLSFKSE 1475
Query: 3012 ------------------ALCDGIRDCFDGSDENPIH-------CKDM---CKGKYRCTN 2917
CDG+ DC DGSDE C++ C C
Sbjct: 1476 PCKKDEFTCNNRNCIPMELQCDGLDDCGDGSDEQGCMQTPTQHTCENNGNPCGDDAYCNQ 1535
Query: 2916 GRCIDVSARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKN 2737
R V R EC FG+C+Q C + + +C C + +
Sbjct: 1536 IRT-SVFCRCKPGFQRNIKGRECADLNECLVFGICSQHC-LNTRGSYKCVCDQNF---QE 1590
Query: 2736 DENECEPLSKSAE---MFITNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYD-- 2572
N C ++K +E ++I N + + + + +++ N G+D Y
Sbjct: 1591 KNNSC--IAKGSEDQALYIANDTDILGFVYPFNYSGSHQQISHVEHNSRITGMDVYYQRN 1648
Query: 2571 -VFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGLITYDFMHNNVYFTESSEQ 2395
+ +T GI + +D R K+ ++ G E I D++ NVY+T+ S
Sbjct: 1649 VIVWSTQFNPGGIFYTMIDAREKRQANS--GLICPEFKRPRDIAVDWVTGNVYWTDHSRM 1706
Query: 2394 NRGVLFDR-----QANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPR 2230
+ + + +I V + + L+ N G ++AV+P + +++WT
Sbjct: 1707 HWFSYYTTHWTSLRYSINVGQLNGPNCTRLLTNMAGEPYAIAVNPKRGMMYWTVIGDHSH 1766
Query: 2229 ILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSF 2050
I A +DG + LV++++ PT + +D ER+YW D I +V +
Sbjct: 1767 IEEAAMDGTL-----------RRILVQKHLQRPTGLTVDHFGERIYWADFELSIIGSVMY 1815
Query: 2049 DGRDRRTVRKFELGDT-PVTMDVLGGYIYLITRQGSIHRMHKFTGKTNKYVQKIREVSPR 1873
DG + G P +DV YIY + I R+ KF G + V + +V
Sbjct: 1816 DGSSPVVSVSSKQGLLHPHRIDVFEDYIYGAGPKNGIFRVQKF-GHGSVEVLTL-DVDKT 1873
Query: 1872 IQIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLCGPGRFFEVST 1693
I V+H K + NPC C + P C+C G+ T
Sbjct: 1874 KSIVVSHRYKQL-----NLPNPCLGLSCDFLCLLNPSG-------ATCVCPEGKHIRNGT 1921
Query: 1692 KKCMQLREKDQEASQCGDYFCYNNAGCSPQKT----CVCPPGFYGRQCEINECSETCWNG 1525
C + D C N C + C C P + G +CE+N CS C NG
Sbjct: 1922 --CHENSLLDDSCKLT----CENGGRCILNEKGDLRCHCWPSYSGGRCEVNHCSNYCQNG 1975
Query: 1524 ETCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSYSFC 1345
TC G T C C +T +C VCE C GSC V ++P +C
Sbjct: 1976 GTCIPSALGRPT---CICALGFTGPNCGKTVCEDSCHNGGSC--VVTAGNQP------YC 2024
Query: 1344 ECDKGWTGPHCRHKADAKVCYGHCFSGGAC----DG----------EGPL---------- 1237
C +TG C++ VC+ +C + +C DG EGP
Sbjct: 2025 HCQADYTGDRCQY----YVCHHYCVNSESCSIGNDGSVECVCPTRYEGPKCEIDKCVRCH 2080
Query: 1236 -----------NLRCSCGDGLTGNRCQNCVGHECLNGGFCSYANSNRSLPHCICPSGFTG 1090
++ C+C +G + CQ C G+ C NGG C + S+P C+C + ++G
Sbjct: 2081 GGHCIINQDNEDIFCNCTNGKIASSCQLCDGY-CYNGGTCQ-LDPETSVPVCVCSTNWSG 2138
Query: 1089 DHCE 1078
CE
Sbjct: 2139 TQCE 2142
Score = 310 bits (794), Expect = 3e-82
Identities = 290/1094 (26%), Positives = 440/1094 (39%), Gaps = 57/1094 (5%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGL-CIPEQKVCNRINDCANFADESNC---TCNENEFRC 6406
D+ED + C C P YF C CI + VC+ DCA+ +DE+NC TC +EF+C
Sbjct: 1131 DEEDERDCPENSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEANCDKKTCGPHEFQC 1190
Query: 6405 QSGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCD 6226
++ CIP RC+ DC+D SDE C + C+ L +F + C+ + CD
Sbjct: 1191 KNNNCIPDHWRCDSQNDCSDNSDEENCKPQTCT-LRDF-------LCSNGDCVSSRFWCD 1242
Query: 6225 GTNDCYDGSDEKDCFVEFDATGGSVSAPRSCD---AKTQFACLATRTCMPKHWQCDGQPD 6055
G DC DGSDE G SV+A ++C+ +K QF C + C+ W+CDG D
Sbjct: 1243 GEFDCADGSDE---------VGISVNAKKNCETSCSKDQFQC-SNGQCLSAKWKCDGHED 1292
Query: 6054 CADGSDEKNCDAK--KCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKG 5881
C G DEKNC+ C+S E+ C S C+ KC+G DC DG DE C TEC
Sbjct: 1293 CKYGEDEKNCEPAFPVCSSSEYMCASGG-CLSASLKCNGETDCVDGSDEMDCVTECKED- 1350
Query: 5880 GNATFRCTNHR-CIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVV 5704
F+C N CIP+ W CDG DC+D GSDE +C G + + +
Sbjct: 1351 ---QFQCRNKAYCIPIRWLCDGIYDCVD-----GSDEENCGRGGSICRADEFLCNNSL-- 1400
Query: 5703 ACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNE-WMCDSGQ-CIDSGRLCDASVDCVD 5530
C+L +CDG DC D DE + C P + C + + C+ ++C+ DC D
Sbjct: 1401 -CKLHFWVCDGEDDCGDNSDEVPDMCVKFLCPPTRPYRCRNDRICLQLEKMCNGINDCGD 1459
Query: 5529 GSDEWVEICS-----LSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQ- 5368
SDE E CS SEP ++ ++C N C+ + CDG DC G DEQ
Sbjct: 1460 NSDE--EHCSGTLSFKSEPCKK---DEFTCNNRN----CIPMELQCDGLDDCGDGSDEQG 1510
Query: 5367 -CDNP-QGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKANCS 5194
P Q C + N C C + C C G+ + ++ + CS
Sbjct: 1511 CMQTPTQHTCENNGNPCGDDAYCNQIRTSVFCRCKPGFQRNIKGRECADLNECLVFGICS 1570
Query: 5193 HFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILM-----VYGHRLKLFTIDGHA 5029
C++ R ++C C + E C + + + + + G H
Sbjct: 1571 QHCLNTRG-SYKCVCDQNF--QEKNNSCIAKGSEDQALYIANDTDILGFVYPFNYSGSHQ 1627
Query: 5028 KATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINS----LPTK 4861
+ + + + + +D + +++ W+ + G GI R NS K
Sbjct: 1628 QISHVEHNSRITGMDVYYQRNVIVWSTQFNPG---GIFYTMIDAREKRQANSGLICPEFK 1684
Query: 4860 GIDGIAVDWLGRNIYYTDRNHD---------------AIAVCDMRGRFNRILLKGTPLND 4726
IAVDW+ N+Y+TD + +I V + G N L +
Sbjct: 1685 RPRDIAVDWVTGNVYWTDHSRMHWFSYYTTHWTSLRYSINVGQLNGP-NCTRLLTNMAGE 1743
Query: 4725 PRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYF 4546
P AI ++P + +++WT G +HI MDG+ ++++Q + ++ P L VD +R+Y+
Sbjct: 1744 PYAIAVNPKRGMMYWTVIGDHSHIEEAAMDGTLRRILVQ-KHLQRPTGLTVDHFGERIYW 1802
Query: 4545 GDAHRDYIASCNYDGSKRRMVL--RGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGT 4372
D I S YDGS + + + + H + VFEDY+Y + N I RV K
Sbjct: 1803 ADFELSIIGSVMYDGSSPVVSVSSKQGLLHPHRIDVFEDYIYGAGPKN-GIFRVQKFGHG 1861
Query: 4371 NRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDNLCIPANTPDLTTSSDN 4192
+ +VL D + + H Q +PC CD LC+ +
Sbjct: 1862 SVEVLTLDVD-KTKSIVVSHRYKQ-----LNLPNPC-LGLSCDFLCL--------LNPSG 1906
Query: 4191 FTCMCAQGFRSEGRSCVSECKPND---FVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVE 4021
TC+C +G +C +D C +CI +
Sbjct: 1907 ATCVCPEGKHIRNGTCHENSLLDDSCKLTCENGGRCILNEKGDLR--------------- 1951
Query: 4020 GVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQF 3841
C +P +G GR N + S C C P T
Sbjct: 1952 --CHCWPSYSG----GRCEVN------HCSNYCQNGGTCIPSALGRPTCICALGFTGP-- 1997
Query: 3840 KCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCKPDFFACFNGTAISKC--IPKEFYC 3667
CG +VC E C +G +C +T+ + C +C YC
Sbjct: 1998 NCG--------KTVC--EDSCHNGG---SCVVTAGNQPYCHCQADYTGDRCQYYVCHHYC 2044
Query: 3666 DGEDDCPEGQDEPDSC-----FGIGECTHEQ-FQCTSGKCIPKRRQCDGTLDCRDGSDEK 3505
+ C G D C + +C ++ +C G CI + D +C +G
Sbjct: 2045 VNSESCSIGNDGSVECVCPTRYEGPKCEIDKCVRCHGGHCIINQDNEDIFCNCTNGKIAS 2104
Query: 3504 GCKKECAIVCDNSC 3463
C+ +CD C
Sbjct: 2105 SCQ-----LCDGYC 2113
Score = 296 bits (757), Expect = 6e-78
Identities = 399/1662 (24%), Positives = 577/1662 (34%), Gaps = 220/1662 (13%)
Frame = -1
Query: 4725 PRAIVLDPLQALVFWTDWGAS-AHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLY 4549
P + LD Q L+FWT+W I R + G N V++ I PN L +D A++LY
Sbjct: 75 PHVLALDECQNLMFWTNWNEQHPSIMRATLTGKNAHVVVST-DILTPNGLTIDHRAEKLY 133
Query: 4548 FGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTN 4369
F D I C YDGS+R ++++ +LAV+++Y++WSDW I R +K TG
Sbjct: 134 FSDGSLGKIERCEYDGSQRHVIVKSGPGTFLSLAVYDNYIFWSDWGRRAILRSNKYTGGE 193
Query: 4368 RKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQ-PARCDNLCIPANTPDLTTSSDN 4192
KVL D ++PMG V S PC+ C +LC L T
Sbjct: 194 TKVLRSDIPHQPMGIIAVANDTNSC-----ELSPCALLNGGCHDLC-------LLTPDGR 241
Query: 4191 FTCMCAQGFRS--EGRSCVSECKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEG 4018
C C +G R+ CV TK C
Sbjct: 242 VNCSC-RGDRTLLASNRCV----------TKNSSCN------------------------ 266
Query: 4017 VCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFK 3838
I +F CG C+ CDG+ C DE+ +CEN C FK
Sbjct: 267 -------IYSEFECGN------GDCVDYVLTCDGIPHCKDKSDEKLLYCENRSCRSG-FK 312
Query: 3837 CGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCKPDFFACFNGTAI------------- 3697
++C+P +CD DC DGSDEL+C++++C F C +GT I
Sbjct: 313 PCYNRRCVPHGKLCDGTNDCGDGSDELDCKVSTCSTVEFRCTDGTCIPRSARCNQNMDCS 372
Query: 3696 --------------------------------SKCIPKEFYCDGEDDCPEGQDE-PDSCF 3616
S C+ + CDG +DC + DE
Sbjct: 373 DASDEKGCNNTDCTHFYKLGVKSTGFIRCNSTSLCVLPSWICDGSNDCGDYSDELKCPVQ 432
Query: 3615 GIGECTHEQFQCTSGKCIPKRRQCDGTLDCRDGSDEKGCKKECA---IVCD-NSCVHADD 3448
+C F C SG+CI CDG DC DG DE C C+ C + C+
Sbjct: 433 NKHKCEENYFGCPSGRCILNTWVCDGQKDCEDGLDELHCDSSCSWNQFACSVHKCISKHW 492
Query: 3447 LCDGKKKCNDGSDEDEE-----ACVIKQLLEKENRKC--GGFACDGIVDCEDGSDE---K 3298
+CDG+ C DG DE + C + + C + CDG DC DGSDE
Sbjct: 493 ICDGEDDCGDGLDESDNICGAVTCAADMFSCQSSHACVPQHWLCDGERDCPDGSDELSSA 552
Query: 3297 GCPD--------LECH--LASNKSLICDGTIDCSSGKDE---------------NNCHNN 3193
GC CH + K +CD DC G DE C+ +
Sbjct: 553 GCAPNNTCDENAFMCHNKVCIPKQFVCDHDDDCGDGSDEFLECGTSCSCRDRLQTGCYGS 612
Query: 3192 GES-----NFF---QCSMQTIK----------EWQVCDGRWDCADGLDESP--EMCASRK 3073
S FF QC + + WQ CDG +DC D DE+P C S +
Sbjct: 613 LTSTVQYDKFFRYRQCGPEEFRCADGRCLVNTLWQ-CDGDFDCPDSSDEAPINPRCTSAE 671
Query: 3072 ARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKGKYRCTNGRCIDV-- 2899
C + +C+ LCD DC DGS+E H + K + C D+
Sbjct: 672 HSCNSSFFMCKNGRCIP-RDGLCDNRDDCGDGSEEPKCHINECLSKKISGCSQDCQDLPI 730
Query: 2898 --SARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENE 2725
+ EC C+Q+C + T +C C GY +++N
Sbjct: 731 SYKCKCWPGFQLKDDGKTCVDIDECSTGFPCSQQCINTYG-TYKCRCTEGYETQPDNQNG 789
Query: 2724 CEPLSKSAEMFITNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYT 2545
C SK ++F L N + + R N N+I IDF Y R +Y
Sbjct: 790 CRKPSKVIDVF-QEAVELKANPCLNIREAASRHGLN---NVI--AIDFDY---REEFIYW 840
Query: 2544 VGI---GNSRVDIRSKKWSDGLIGSWGEEESTAGLITYDFMHNNVYFTESSEQNRGVLFD 2374
+ SR++ SD I W G + N+Y+ + E
Sbjct: 841 IDSSRPNGSRINRMCLNGSD--IKVWWRRGDELG------VGRNLYWIDCCE-------- 884
Query: 2373 RQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIA 2194
+I T+ +I +L +D + ++W A I +N+DG +
Sbjct: 885 -YPHIGRVGMDGTNQSVVIETKISRPMALTIDYVNHRLYW---ADENHIEFSNMDG---S 937
Query: 2193 QPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETV-SFDGRDRRTVRKF 2017
K +Q ++ +FE + +YW D +++ V G DR ++
Sbjct: 938 HRHKVPNQDIPGVIALTLFE----------DYIYWTDGKTKSLSRVHKTSGADRLSLIYS 987
Query: 2016 ELGDTPVTMDVLGGYIYLITRQ-GSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKH 1840
T + +Y RQ + H TN Y +A +
Sbjct: 988 WHAITDI-------QVYHSYRQPDGPGKTHTCACPTNFY--------------LAADNRT 1026
Query: 1839 TVSHITHQKNPCQSDYC-----PSNTV--CVPDQDKNGILIPKCLCGPGRFFEVSTKKCM 1681
+S+ T + C++D C +TV C D+ P+ C PGR F+ T C
Sbjct: 1027 CLSNCTASQFRCKTDKCIPFWWKCDTVDDCGDGSDEPDD-CPEFKCQPGR-FQCGTGLCA 1084
Query: 1680 QLREKDQEASQCGDYFCYNNAG---CSPQKTCV-----------CPPGFYGRQCEINECS 1543
+ CGD N G C+ K C+ C R C N CS
Sbjct: 1085 LPAFICDGENDCGDNSDELNCGQFKCTKNKKCIPVNLRCNGQDDCGDEEDERDCPENSCS 1144
Query: 1542 ETCWNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRG-SCKTVPCPKDEPH 1366
+ C + + VC + +S N + CGP CK C D
Sbjct: 1145 PDYFQ---CKTTKHCISKLWVCDEDPDCADASDEANCDKKTCGPHEFQCKNNNCIPDHWR 1201
Query: 1365 CRSYSFC--ECDKGWTGPHCRHKADAKVCYGHCFSGGA-CDGEG-----------PLNLR 1228
C S + C D+ P D G C S CDGE +N +
Sbjct: 1202 CDSQNDCSDNSDEENCKPQTCTLRDFLCSNGDCVSSRFWCDGEFDCADGSDEVGISVNAK 1261
Query: 1227 CSCGDGLTGNRCQNCVGHECLNGGF-------CSYANSNRSLPHCICPSGFTGDHCEEYL 1069
+C + ++ Q C +CL+ + C Y ++ C F EY+
Sbjct: 1262 KNCETSCSKDQFQ-CSNGQCLSAKWKCDGHEDCKYGEDEKN-----CEPAFPVCSSSEYM 1315
Query: 1068 C-KDACPFGS-KCT-----YDITKPMDPIT-CSCEQNAAAHNTDCSP------------- 952
C C S KC D + MD +T C +Q + C P
Sbjct: 1316 CASGGCLSASLKCNGETDCVDGSDEMDCVTECKEDQFQCRNKAYCIPIRWLCDGIYDCVD 1375
Query: 951 ------------ICQKQPNWCHN----------------GGRCLDTPGYPGKCKCLPRFA 856
IC+ C+N G + P K C P
Sbjct: 1376 GSDEENCGRGGSICRADEFLCNNSLCKLHFWVCDGEDDCGDNSDEVPDMCVKFLC-PPTR 1434
Query: 855 GPRC---DVPVQCDDYCTNNSKCTITNGTHFECDCKPGFKGLRCEQETKCSECSNEAKCI 685
RC + +Q + C + C N C FK C+++ C+N
Sbjct: 1435 PYRCRNDRICLQLEKMCNGINDCG-DNSDEEHCSGTLSFKSEPCKKDE--FTCNNRNCIP 1491
Query: 684 KKPSGTVICQCPQGLGGEYCEKITATSCHQLECKNGGYCLKPDPSAN--RTSPTCLCSPG 511
+ + C G + C + Q C+N G D N RTS C C PG
Sbjct: 1492 MELQCDGLDDCGDGSDEQGCMQTPT----QHTCENNGNPCGDDAYCNQIRTSVFCRCKPG 1547
Query: 510 F----KGLLCSS-NACENFCLHDGNCTLDEYFEPQCECYQAF 400
F KG C+ N C F + +C L+ +C C Q F
Sbjct: 1548 FQRNIKGRECADLNECLVFGICSQHC-LNTRGSYKCVCDQNF 1588
Score = 121 bits (303), Expect = 3e-25
Identities = 84/273 (30%), Positives = 111/273 (39%), Gaps = 4/273 (1%)
Frame = -1
Query: 1287 CYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQ-NCVGHECLNGGFCSYANSNRSLPHCI 1111
C C +GG C +LRC C +G RC+ N + C NGG C + R P CI
Sbjct: 1932 CKLTCENGGRCILNEKGDLRCHCWPSYSGGRCEVNHCSNYCQNGGTCIPSALGR--PTCI 1989
Query: 1110 CPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMDPITCSCEQNAAAHNTDCSPICQKQPN 931
C GFTG +C + +C+D+
Sbjct: 1990 CALGFTGPNCGKTVCEDS------------------------------------------ 2007
Query: 930 WCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSKCTITNGTHFECDCKPG 751
CHNGG C+ T G C C + G RC V C YC N+ C+I N EC C
Sbjct: 2008 -CHNGGSCVVTAGNQPYCHCQADYTGDRCQYYV-CHHYCVNSESCSIGNDGSVECVCPTR 2065
Query: 750 FKGLRCEQETKCSECSNEAKCIKKPSGTVICQCPQGLGGEYCEKITATSCHQLE--CKNG 577
++G +CE + KC C I + + + C C G KI A+SC + C NG
Sbjct: 2066 YEGPKCEID-KCVRCHGGHCIINQDNEDIFCNCTNG-------KI-ASSCQLCDGYCYNG 2116
Query: 576 GYC-LKPDPSANRTSPTCLCSPGFKGLLCSSNA 481
G C L P+ S P C+CS + G C A
Sbjct: 2117 GTCQLDPETSV----PVCVCSTNWSGTQCERPA 2145
Score = 108 bits (270), Expect = 2e-21
Identities = 72/259 (27%), Positives = 100/259 (37%), Gaps = 8/259 (3%)
Frame = -1
Query: 1134 NRSLPHCICPSG--FTGDHCEEYL-----CKDACPFGSKCTYDITKPMDPITCSCEQNAA 976
N S C+CP G C E CK C G +C I + C C + +
Sbjct: 1903 NPSGATCVCPEGKHIRNGTCHENSLLDDSCKLTCENGGRC---ILNEKGDLRCHCWPSYS 1959
Query: 975 AHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSKC 796
+ + N+C NGG C+ + C C F GP C V C+D C N C
Sbjct: 1960 GGRCEVNHCS----NYCQNGGTCIPSALGRPTCICALGFTGPNCGKTV-CEDSCHNGGSC 2014
Query: 795 TITNGTHFECDCKPGFKGLRCEQETKCSECSNEAKCIKKPSGTVICQCPQGLGGEYCEKI 616
+T G C C+ + G RC+ C N C G+V C CP G CE
Sbjct: 2015 VVTAGNQPYCHCQADYTGDRCQYYVCHHYCVNSESCSIGNDGSVECVCPTRYEGPKCEID 2074
Query: 615 TATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCLHDGNCTLD- 439
CH GG+C+ N+ + C+ + S C+ +C + G C LD
Sbjct: 2075 KCVRCH------GGHCI-----INQDNEDIFCNCTNGKIASSCQLCDGYCYNGGTCQLDP 2123
Query: 438 EYFEPQCECYQAFIGDRCQ 382
E P C C + G +C+
Sbjct: 2124 ETSVPVCVCSTNWSGTQCE 2142
Score = 85.1 bits (209), Expect = 2e-14
Identities = 52/174 (29%), Positives = 73/174 (41%), Gaps = 8/174 (4%)
Frame = -1
Query: 834 VQCDDYCTNN---SKCTITNGTHFECDCKPGFKGLRCEQETKCSE-----CSNEAKCIKK 679
+ CD C N + C G H + C + + + C N +CI
Sbjct: 1894 LSCDFLCLLNPSGATCVCPEGKHI--------RNGTCHENSLLDDSCKLTCENGGRCILN 1945
Query: 678 PSGTVICQCPQGLGGEYCEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGL 499
G + C C G CE C C+NGG C+ PSA PTC+C+ GF G
Sbjct: 1946 EKGDLRCHCWPSYSGGRCE---VNHCSNY-CQNGGTCI---PSA-LGRPTCICALGFTGP 1997
Query: 498 LCSSNACENFCLHDGNCTLDEYFEPQCECYQAFIGDRCQYRIHQHAVIFSDDDS 337
C CE+ C + G+C + +P C C + GDRCQY + H + S+ S
Sbjct: 1998 NCGKTVCEDSCHNGGSCVVTAGNQPYCHCQADYTGDRCQYYVCHHYCVNSESCS 2051
Score = 65.5 bits (158), Expect = 2e-08
Identities = 66/248 (26%), Positives = 88/248 (34%), Gaps = 51/248 (20%)
Frame = -1
Query: 5766 CAAGRTSFHVPSR--CADETCVVACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWM 5593
C +S ++ S C + CV + CDGI C D DEK +R C+
Sbjct: 258 CVTKNSSCNIYSEFECGNGDCVDY----VLTCDGIPHCKDKSDEKLLYCENRSCRSGFKP 313
Query: 5592 CDSGQCIDSGRLCDASVDCVDGSDEW---VEICSLSE---------PPRRGCPSGWSC-- 5455
C + +C+ G+LCD + DC DGSDE V CS E P C C
Sbjct: 314 CYNRRCVPHGKLCDGTNDCGDGSDELDCKVSTCSTVEFRCTDGTCIPRSARCNQNMDCSD 373
Query: 5454 -------------------------LLTNGTIGCLQEQQLCDGRRDCMSGIDE------- 5371
+ N T C+ +CDG DC DE
Sbjct: 374 ASDEKGCNNTDCTHFYKLGVKSTGFIRCNSTSLCVLPSWICDGSNDCGDYSDELKCPVQN 433
Query: 5370 --QCDNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKANC 5197
+C+ C S R + TW C C+DG D+ C S S + C
Sbjct: 434 KHKCEENYFGCPSGRCILN-TWVCDGQK-----DCEDG-----LDELHCDSSCSWNQFAC 482
Query: 5196 S-HFCIDR 5176
S H CI +
Sbjct: 483 SVHKCISK 490
Score = 63.2 bits (152), Expect = 8e-08
Identities = 50/198 (25%), Positives = 76/198 (38%), Gaps = 27/198 (13%)
Frame = -1
Query: 1812 NPCQSDYCPSNTVCVPDQDKNGILIPKCLC-----GPGRFFEVSTKKCMQLR-------- 1672
N C S+YC + C+P + + P C+C GP V C
Sbjct: 1966 NHC-SNYCQNGGTCIP----SALGRPTCICALGFTGPNCGKTVCEDSCHNGGSCVVTAGN 2020
Query: 1671 ------EKDQEASQCGDY----FCYNNAGCS----PQKTCVCPPGFYGRQCEINECSETC 1534
+ D +C Y +C N+ CS CVCP + G +CEI++C
Sbjct: 2021 QPYCHCQADYTGDRCQYYVCHHYCVNSESCSIGNDGSVECVCPTRYEGPKCEIDKCVRC- 2079
Query: 1533 WNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSY 1354
+G C + + ++ C+C + SSC +C+G C G+C+ P S
Sbjct: 2080 -HGGHCIINQ--DNEDIFCNCTNGKIASSC--QLCDGYCYNGGTCQLDPET-------SV 2127
Query: 1353 SFCECDKGWTGPHCRHKA 1300
C C W+G C A
Sbjct: 2128 PVCVCSTNWSGTQCERPA 2145
>gi|47210425|emb|CAF92450.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 4260
Score = 677 bits (1748), Expect = 0.0
Identities = 562/1951 (28%), Positives = 805/1951 (40%), Gaps = 244/1951 (12%)
Frame = -1
Query: 6564 DTKYC----STRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESN--C---------- 6433
D+K+C TR C+PG F C NG CI Q C+ NDC + +DE C
Sbjct: 2226 DSKHCIPDNGTR-CQPGQFTCMNGHCIRAQWKCDNENDCGDGSDELERVCGPKPKFTIVA 2284
Query: 6432 --TCNENEFRCQSGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATT 6259
TC F C +G C+P RC+H DC D SDE+GC FR C EF
Sbjct: 2285 FHTCEPTVFTCGNGRCVPYHYRCDHYDDCGDNSDELGCLFRPCDPSREF-------TCNN 2337
Query: 6258 SQCIHPSWKCDGTNDCYDG--SDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMP 6085
+CI + C+G N+CYD SDE++C R+C + Q C +T C+P
Sbjct: 2338 GRCIAKDYVCNGINNCYDNGTSDEQNC------------PERTCQPE-QTKCQSTNICIP 2384
Query: 6084 KHWQCDGQPDCADGSDEK--NCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEH 5911
+ + CDG DC D SDE +C A C+ EF C SS +CIP CDG DC D DE
Sbjct: 2385 RSYLCDGDNDCGDMSDESPTHCVASTCSQSEFRC-SSGRCIPARWYCDGGADCSDSSDEP 2443
Query: 5910 QCETECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPS 5731
T FRC + RCI W CDG +DC D + D+ A RT +
Sbjct: 2444 LSCTPQVRTCNTEQFRCDDGRCIASTWICDGDNDCGDMSDE---DQRHNCANRTCSNAEF 2500
Query: 5730 RCAD-ETCVVACELTAVLCDGIQDCSDGFDE-KNCASLDRQCKPNEWMCDSGQCIDSGRL 5557
C + + C +CDG DC+D DE +NC R C NE+ C +G CI S
Sbjct: 2501 TCVNNQPPQRKCIPRDWVCDGDADCADALDEHQNCTR--RSCGVNEFTCSNGLCIRSSYR 2558
Query: 5556 CDASVDCVDGSDEWVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGI 5377
CD DC DGSDE + + C +G C+ +CDG DC
Sbjct: 2559 CDRRNDCGDGSDEQGCTYQACQQHQFTCQNG----------RCISRDFVCDGDNDCGDES 2608
Query: 5376 DE-----------------QCDNPQGNCSSTRNSCDQTWNCQRHAGFESC---------- 5278
DE +CDN G+C S CD+ +C ++ + C
Sbjct: 2609 DELEHMCHTPAPTCPPGEFRCDN--GHCISLSRVCDRNDDCSDNSDEKGCGVNECTDPSI 2666
Query: 5277 ----------------SCDDGYHLSPYDKKTCLRSPSCPKAN--CSHFCIDRRDVG-HQC 5155
+C GY L D KTC C + CS C VG + C
Sbjct: 2667 HHCDHSCTDTPTSFICTCRPGYRLMS-DGKTCDDVNECAETPRVCSQVC--ENTVGSYVC 2723
Query: 5154 FCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLTNGVALDYDV 4975
CAPG++ + CR+N I ++ + L+ + DG A + +L LT+ VALD+D
Sbjct: 2724 KCAPGFLREPDGHSCRQNSDIAPYLIFSNRYYLRNLSTDGAAYSLILQGLTSVVALDFDR 2783
Query: 4974 KSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHD 4795
+YW DV+ + I MS + V+ + G +G+AVDW+ R +Y+ D D
Sbjct: 2784 VDRRLYWIDVS----RRVIERMSYNGSNREVVVTGVLHG-EGLAVDWIARKLYWVDSFSD 2838
Query: 4794 AIAVCDMRGRFNRILLKGTP-------LNDPRAIVLDPLQALVFWTDWGASAHIGRMNMD 4636
+ V ++ GRF + L + +PRAIVL P V+WTDWG A IGR+ MD
Sbjct: 2839 CLKVSELDGRFVKKLAEHCVDANNTFCFENPRAIVLHPKYGFVYWTDWGDKAFIGRVGMD 2898
Query: 4635 GSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIF 4456
G+N+ I+ + + WPN + +D +LY+ DAH YI + DG R V G++ H F
Sbjct: 2899 GTNKAPIITTK-LEWPNGITIDYTNDKLYWSDAHLSYIEFSDLDGQHRHTVYDGNLPHPF 2957
Query: 4455 ALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTA 4276
AL VFED VYW+DW+ T+E+ +K G+ R+ L+ + +RP + HP Q +
Sbjct: 2958 ALTVFEDTVYWTDWNTRTVEKGNKYDGSGRQALV-NTTHRPFDIHVCHPYRQPI-----V 3011
Query: 4275 RHPCS-QPARCDNLCIPANTPDLTTSSDNFTCMCAQGFRSEGRSCVSECKP----NDFVC 4111
+PC+ C +LC+ + TC C F + V+ C P + C
Sbjct: 3012 TNPCAVNNGGCSHLCL------IRHGGQEHTCECPDHFLTIQIGGVTRCLPMCTSTQYRC 3065
Query: 4110 TKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYAS 3931
+CI WW+ CP C GQF C C
Sbjct: 3066 ANNERCIPIWWKCDGQRDCRDGSDE----PSTCPVRHCRLGQFQCN------DGNCTSPH 3115
Query: 3930 KLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDE--L 3757
LC+ +DC G DE+P C +C Q++C +K+ CIP + CD E DC D SDE
Sbjct: 3116 LLCNSHQDCHDGSDEDPVLCATHQCENHQWQCANKR-CIPESWQCDGEDDCGDQSDEDPA 3174
Query: 3756 NCEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEP-DSCFGIG-EC-THEQF 3586
+C +C+P F C NG +CIP+ + CD ++DC + DEP + C G C H +F
Sbjct: 3175 HCSSRTCRPGQFKCRNG----RCIPQSWKCDVDNDCGDNSDEPLEECMGPAYRCDNHTEF 3230
Query: 3585 QC-TSGKCIPKRRQCDGTLDCRDGSDEKGCKKECAIVCD---------NSCVHADDLCDG 3436
C T+ +C+P C+G DCRD SDE+GC + + CD + C+ CDG
Sbjct: 3231 SCRTNYRCVPMWSVCNGHNDCRDDSDEQGCDE---LTCDPTGDFRCNNHRCIPLRWRCDG 3287
Query: 3435 KKKCNDGSDEDEEACVIKQLLEKE----NRKC--GGFACDGIVDCEDGSDEKGCPDLECH 3274
C D SDE +C + E E N +C + CD DCED SDE+ C CH
Sbjct: 3288 DDDCGDNSDE--RSCTPRTCTESEYRCDNLRCIPNRWVCDHDNDCEDNSDERDCELRTCH 3345
Query: 3273 LAS---------NKSLICDGTIDCSSGKDENNCHN---NG-------------------- 3190
++ CDG DC DE +C NG
Sbjct: 3346 PGYFQCTSGHCISERFKCDGNPDCLDYTDETSCPTRFPNGTYCPPFMFECKNHVCVQPHW 3405
Query: 3189 ------------------------ESNF-FQC-SMQTIKEWQVCDGRWDCADGLDESPEM 3088
E+ F F+C + + I ++C+ DC DG DE PE
Sbjct: 3406 KCDGDDDCGDNSDEELHLCIDIQCETPFRFRCDNNRCIYSHELCNSVNDCGDGSDEIPEN 3465
Query: 3087 CASRKARCFRIGYCDDKK------QCLDVSTALCDGIRDCFDGSDENPIH------CKD- 2947
C R + G C D++ C+ + A CD DC D SDE H C D
Sbjct: 3466 C-ERNSPNPTHGPCTDEEYKCSNGHCIPLPYA-CDDYDDCGDQSDELGCHRGSTHTCSDN 3523
Query: 2946 MCKGKYRCTNGR--CIDVSARXXXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTAR 2773
+C+ + CT+ R + S R EC +G C Q+C +
Sbjct: 3524 ICE--HNCTDLREGGLLCSCRPGYKPRATEKHMCEDVN-ECEVYGTCPQECKNT-KGSFE 3579
Query: 2772 CHCAPGYARTKNDEN-ECEPLSKSAEMFITNGNRLHLMSLENSQ---------------- 2644
C CA G+ EC + + + R+ +L + Q
Sbjct: 3580 CFCAKGFVSIGEPHGTECAAQGNPPVLLLPDNVRIRRFNLSSQQYSDYVDNAEHIQALDY 3639
Query: 2643 -----------VSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTV-GIGNSRVDIRSK-- 2506
+S P+ ++ L F Y + +TV G G+ I+
Sbjct: 3640 LWDPEGQGLSKMSACMPLHRYRLGL--SYCCFLYGCAAGVVYWTVLGRGSEFGSIKCAYM 3697
Query: 2505 -KWSDGLIGSWGEEESTAGL--------ITYDFMHNNVYFTESSEQNRGVLFDRQANIYV 2353
++D GS +E L I D++ ++Y+T+S I V
Sbjct: 3698 PTFND--YGSNPVKEVDLNLRYVSKPDGIALDWVGRHIYWTDSGTNR----------IEV 3745
Query: 2352 AKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGS 2173
AK + LI ++AV+P+ R+++WT PRI +A +DG
Sbjct: 3746 AKLDGRYRKWLIHTDLDQPAAIAVNPLLRMMYWTDWGRKPRIETAWMDG----------- 3794
Query: 2172 QPHKALVERNIFEPTSMVLDFSN-ERLYWIDVLKRTIETVSFDGRDRRT----------- 2029
Q LV+ ++ PT + +D+ N R+YW D + T+E++ DG DR+
Sbjct: 3795 QNRAVLVDEDLGWPTGLTVDYLNGNRIYWCDSKENTVESMKPDGTDRKAVISGGQSSALS 3854
Query: 2028 --------------VRKFELGDTPVTMDVLGGYIYLITRQ-GSIHRMHKFTGKTNKYVQK 1894
V F P ++DV G++Y T+ G + R +KF N + K
Sbjct: 3855 GFSKLQKETPHMHLVSTFSDIGHPYSLDVFEGHLYWTTKDTGEVWRTNKF---GNGHKVK 3911
Query: 1893 IREVSPRI-QIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLCGP 1717
+ ++P + Q+RV +H + NPC++ + CL P
Sbjct: 3912 VLTINPWLTQVRVYQEHRHNQT----VPNPCKN-----------------VCSHLCLLRP 3950
Query: 1716 GRFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCSPQKTCVCPPGFYGRQCEINECSET 1537
G + T C Q G F ++ G + PP C
Sbjct: 3951 GGY----TCACPQ-----------GSSFAESDFGIC--DAAIEPPVTMPPACR------- 3986
Query: 1536 CWNGETCAVQEFGSTTNVVCHCPSNYTQSSC 1444
C NG TC E G C CP YT S C
Sbjct: 3987 CMNGGTCYTDEGGMPK---CKCPYGYTGSYC 4014
Score = 425 bits (1093), Expect = e-117
Identities = 278/810 (34%), Positives = 394/810 (48%), Gaps = 15/810 (1%)
Frame = -1
Query: 6549 STRVCRPGYFNCGNGL-CIPEQKVCNRINDCANFADESNCTCNENEFRCQSGACIPSKAR 6373
S RVC C G+ +P Q+ C + D +N + C N F C +G C+P+ R
Sbjct: 527 SQRVC-----GCPYGMKLLPNQRTC--VEDPSN--EPPTLQCGANSFSCGNGKCVPNSYR 577
Query: 6372 CNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDGTNDCYDGSDE 6193
C+ + DC+D SDE+ C N + CA T +C+ +W+CDG NDC+D SDE
Sbjct: 578 CDGVDDCHDNSDEVDCGVNNSTC-----SPTAFTCANT-RCVPAAWRCDGHNDCFDNSDE 631
Query: 6192 KDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADGSDEKNCD-AK 6016
C AP +C A QF C + C+P W+CD DC DGSDE +C
Sbjct: 632 SSC---------PAPAPGTCPA-NQFTC-SNHRCVPHSWRCDTDNDCGDGSDEADCQLGS 680
Query: 6015 KCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNATFRC-TNHRCIP 5839
C +F C +CI CDG RDC DG DE C C + F+C + H+CI
Sbjct: 681 TCHPGQFQC-PDHRCIDPSYVCDGDRDCVDGADERGCIYNCTAN----EFKCASGHQCIN 735
Query: 5838 MAWRCDGTDDCMDNAKSLGSDEVDCAA---GRTSFHVPSRC-ADETCVVACELTAVLCDG 5671
+RCDG DC D SDE C G +C +D TC+ + CDG
Sbjct: 736 GYYRCDGVFDCTDR-----SDERACPTRPPGMCHHESEFQCQSDGTCIP----STWECDG 786
Query: 5670 IQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASVDCVDGSDEWVEICSLSE 5491
DC D DE + A R C + CD+G C+ +CD DC D SDE
Sbjct: 787 HPDCEDSSDEHH-ACPPRTCPSTFFRCDNGNCVLRSWICDGDNDCRDMSDE----RDCPT 841
Query: 5490 PPRRGCPS-GWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSSTRNSCDQT 5314
PP R CPS W C G C+ +CD DC +G DE Q +CS C T
Sbjct: 842 PPFR-CPSWQWQC---PGHSVCINLTTVCDNTPDCPNGADESPLCNQESCSDNNAGC--T 895
Query: 5313 WNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSC-PKANCSHFCIDRRDVGHQCFCAPGY 5137
C + C+C GY LS D KTC C P CS C + R +C C GY
Sbjct: 896 HGCIQGPFGAQCTCPVGYQLS-NDSKTCGDVDECSPPGICSQHCFNERG-SFRCHCQDGY 953
Query: 5136 ILSENQKDCRRNDTIEAEILMVYGHRLKL--FTIDGHAKATLLSNLTNGVALDYDVKSDL 4963
L +Q+ C+ +D +A +L+ +++ T + +L+ + N VALD+D +D
Sbjct: 954 ALEADQRTCKVSDLRQAFLLVASRNQIVQDDITSQPNVVHSLVRDGRNIVALDFDSVTDR 1013
Query: 4962 VYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAV 4783
VYW+D + D I S SN + VI + +AVDW+GRN+Y+TD + + V
Sbjct: 1014 VYWSDTSQD----RIWSASNNGSDRTVIFDSGVTVTESLAVDWVGRNLYWTDYVLETVEV 1069
Query: 4782 CDMRGRFNRILLKGTPLNDPRAIVLDPLQA--LVFWTDWGASAHIGRMNMDGSNEQVILQ 4609
+ G +R +L + +PR +VLDP + L+FWTDWG + I R +MDG VI+
Sbjct: 1070 SKLDGT-HRTVLVSENVTNPRGLVLDPRSSAHLMFWTDWGRNPRIERASMDGKLRTVIVN 1128
Query: 4608 DRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGS--VRHIFALAVFED 4435
+ + WPN L +D P LYF DA+ D+I C+Y+G+ R+ VL ++H A+ +FED
Sbjct: 1129 SK-LYWPNGLTIDYPNNLLYFADAYLDFIDYCDYNGNNRKQVLASDLVLQHPHAITIFED 1187
Query: 4434 YVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQP 4255
+VYW+D + + + R HK G N+ V++ + +PMG VHP+ Q G R PCS
Sbjct: 1188 FVYWTDRYINRVMRAHKWHGENQTVMLFNLP-QPMGLVAVHPARQPAGGNSCLRSPCS-- 1244
Query: 4254 ARCDNLCIPANTPDLTTSSDNFTCMCAQGF 4165
++C+ + ++C C G+
Sbjct: 1245 ----HICLLS-----AVGPAYYSCACPSGW 1265
Score = 370 bits (949), Expect = e-100
Identities = 401/1663 (24%), Positives = 637/1663 (38%), Gaps = 116/1663 (6%)
Frame = -1
Query: 5199 CSHFCIDRRDVGHQ-----CFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTI-- 5041
C+HFC + G C CA G + ++N K C + + ++Y + ++
Sbjct: 1888 CAHFCFALPEYGSDGQNKVCSCAFGNLGADN-KGC----VVSRDDYLIYTTESTVRSLRL 1942
Query: 5040 --DGHAKATLLSNLTN-GVALDYDVKSDLVYWTDVAHDG-NKAGITSMSNQPNTYRVINS 4873
D HA + N+ VALD+D+ +Y+T + G +K S+S P + V+ +
Sbjct: 1943 DPDDHALPFPVVNVPRTSVALDFDLTERRIYFTQSSGAGASKISYVSLS-APTSTPVVVA 2001
Query: 4872 LPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQA 4693
DGIA DW+ R IYY+D + +I + G +++ ++ PRAI+LDP +
Sbjct: 2002 FDLGAPDGIAYDWINRRIYYSDFVNQSINSMSVEGSQRTVVVH---VSRPRAIMLDPCRG 2058
Query: 4692 LVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASC 4513
++WTDWG A I R + G N + + + ++ WPN L +D +RLY+ DA I
Sbjct: 2059 YMYWTDWGTHAKIERATL-GGNFRTDIVNSSLVWPNGLTLDYEDERLYWADASLQKIERS 2117
Query: 4512 NYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRP 4333
+ GS R +++ ++ + FA+ +F+ ++YW+DW+ +I R +K G+ ++V+IQ+ RP
Sbjct: 2118 SLTGSDREVIVSTAI-YPFAMTMFDQFIYWTDWNTRSIYRANKHDGSGQRVMIQNLPSRP 2176
Query: 4332 MGFKIVHPSLQSMGSLKTARHPCSQ-PARCDNLCIPANTPDLTTSSDNFTCMC---AQGF 4165
M ++ Q + PC Q C ++C P + C C + +
Sbjct: 2177 MDIHVLASRKQ-----QQCDSPCQQFNGGCSHICTP--------GPNGAECHCPSEGRWY 2223
Query: 4164 RSEGRSCV----SECKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFP- 4000
++ + C+ + C+P F C + CI + W+ +E VC P P
Sbjct: 2224 LADSKHCIPDNGTRCQPGQFTCMNGH-CIRAQWKCDNENDCGDGSDE---LERVCGPKPK 2279
Query: 3999 --------CIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEA- 3847
C F CG +C+ CD DC GD+ + C C +
Sbjct: 2280 FTIVAFHTCEPTVFTCG------NGRCVPYHYRCDHYDDC--GDNSDELGCLFRPCDPSR 2331
Query: 3846 QFKCGDKKKCIPLTSVCDKEKDCDDG--SDELNCEITSCKPDFFACFNGTAISKCIPKEF 3673
+F C + +CI VC+ +C D SDE NC +C+P+ C + + CIP+ +
Sbjct: 2332 EFTC-NNGRCIAKDYVCNGINNCYDNGTSDEQNCPERTCQPEQTKC---QSTNICIPRSY 2387
Query: 3672 YCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQCDGTLDCRDGSDE----- 3508
CDG++DC + DE + C+ +F+C+SG+CIP R CDG DC D SDE
Sbjct: 2388 LCDGDNDCGDMSDESPTHCVASTCSQSEFRCSSGRCIPARWYCDGGADCSDSSDEPLSCT 2447
Query: 3507 ---KGCKKECAIVCDNSCVHADDLCDGKKKCNDGSDED-------------EEACVIKQL 3376
+ C E D C+ + +CDG C D SDED E CV Q
Sbjct: 2448 PQVRTCNTEQFRCDDGRCIASTWICDGDNDCGDMSDEDQRHNCANRTCSNAEFTCVNNQ- 2506
Query: 3375 LEKENRKC--GGFACDGIVDCEDGSDE-KGCPDLEC---------HLASNKSLICDGTID 3232
RKC + CDG DC D DE + C C L S CD D
Sbjct: 2507 --PPQRKCIPRDWVCDGDADCADALDEHQNCTRRSCGVNEFTCSNGLCIRSSYRCDRRND 2564
Query: 3231 CSSGKDENNC-HNNGESNFFQC-SMQTIKEWQVCDGRWDCADGLDESPEMCASRKARCFR 3058
C G DE C + + + F C + + I VCDG DC D DE MC + C
Sbjct: 2565 CGDGSDEQGCTYQACQQHQFTCQNGRCISRDFVCDGDNDCGDESDELEHMCHTPAPTCPP 2624
Query: 3057 IGYCDDKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKGKYRCTNGRCIDVSARXXXX 2878
+ D C+ +S +CD DC D SDE + + C D
Sbjct: 2625 GEFRCDNGHCISLS-RVCDRNDDCSDNSDEKGCGVNECTDPSIHHCDHSCTDTPTSFICT 2683
Query: 2877 XXXXXXXXXXXXGA----ECHHF-GVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPL 2713
EC VC+Q C C CAPG+ R + D + C
Sbjct: 2684 CRPGYRLMSDGKTCDDVNECAETPRVCSQVCENTVGSYV-CKCAPGFLR-EPDGHSCRQN 2741
Query: 2712 SKSAEMFITNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIG 2533
S A I + NR +L +L + +++ + + + +D L Y + +
Sbjct: 2742 SDIAPYLIFS-NRYYLRNLSTDGAA-----YSLILQGLTSVVALDFDRVDRRL-YWIDVS 2794
Query: 2532 NSRVDIRSKKWSDGLIGSWGEEESTAGLITYDFMHNNVYFTESSEQNRGV--LFDRQANI 2359
++ S S+ + G + D++ +Y+ +S V L R
Sbjct: 2795 RRVIERMSYNGSNREVVVTGVLHGEG--LAVDWIARKLYWVDSFSDCLKVSELDGRFVKK 2852
Query: 2358 YVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKT 2179
D + N ++ + P ++WT I +DG T
Sbjct: 2853 LAEHCVDANNTFCFENP----RAIVLHPKYGFVYWTDWGDKAFIGRVGMDG--------T 2900
Query: 2178 GSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTP 1999
P ++ + P + +D++N++LYW D IE DG+ R TV L P
Sbjct: 2901 NKAP---IITTKLEWPNGITIDYTNDKLYWSDAHLSYIEFSDLDGQHRHTVYDGNL-PHP 2956
Query: 1998 VTMDVLGGYIYLIT-RQGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHIT 1822
+ V +Y ++ + +K+ G + + + I V HP + +
Sbjct: 2957 FALTVFEDTVYWTDWNTRTVEKGNKYDGSGRQAL--VNTTHRPFDIHVCHPYRQPI---- 3010
Query: 1821 HQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLCGPGRFFEV---STKKCMQLREKDQEAS 1651
NPC + + +C+ ++G C C P F + +C+ + Q
Sbjct: 3011 -VTNPCAVNNGGCSHLCL---IRHGGQEHTCEC-PDHFLTIQIGGVTRCLPMCTSTQ--- 3062
Query: 1650 QCGDYFCYNNAGCSP-------QKTC--------VCPPGFYGRQCEINECSETCWNGETC 1516
Y C NN C P Q+ C CP R C + + N C
Sbjct: 3063 ----YRCANNERCIPIWWKCDGQRDCRDGSDEPSTCPV----RHCRLGQFQ---CNDGNC 3111
Query: 1515 AVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSYSFCECD 1336
++ CH S+ CAT+ CE + C C + C C
Sbjct: 3112 TSPHLLCNSHQDCHDGSDEDPVLCATHQCE---NHQWQCANKRCIPESWQCDGEDDCGDQ 3168
Query: 1335 KGWTGPHCRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQNCVGHECLNGG 1156
HC + + C +G ++ CGD
Sbjct: 3169 SDEDPAHCSSRT-CRPGQFKCRNGRCIPQSWKCDVDNDCGD------------------- 3208
Query: 1155 FCSYANSNRSLPHCICPSGFTGDHCEEYLCK---------DACPFGSKCTYDITKP-MDP 1006
NS+ L C+ P+ + D+ E+ C+ C + C D + D
Sbjct: 3209 -----NSDEPLEECMGPA-YRCDNHTEFSCRTNYRCVPMWSVCNGHNDCRDDSDEQGCDE 3262
Query: 1005 ITCSCEQNAAAHNTDCSPICQKQPNW-CHNGGRCLDTPGYPGKCKCLPRFAGP---RCDV 838
+TC + +N C P+ W C C D + C PR RCD
Sbjct: 3263 LTCDPTGDFRCNNHRCIPL-----RWRCDGDDDCGDN---SDERSCTPRTCTESEYRCD- 3313
Query: 837 PVQCDD---YCTNNSKCTITNGTHFECD---CKPGFKGLRCEQETKCSE---CSNEAKCI 685
++C C +++ C N +C+ C PG+ +C SE C C+
Sbjct: 3314 NLRCIPNRWVCDHDNDCE-DNSDERDCELRTCHPGY--FQCTSGHCISERFKCDGNPDCL 3370
Query: 684 KKPSGTVICQCPQGL-GGEYCEKITATSCHQLECKNGGYCLKP 559
T CP G YC ECKN C++P
Sbjct: 3371 DYTDET---SCPTRFPNGTYCPPF------MFECKN-HVCVQP 3403
Score = 353 bits (907), Expect = 2e-95
Identities = 262/889 (29%), Positives = 381/889 (42%), Gaps = 88/889 (9%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADE-----SNCTCNENEFRC 6406
DED C+T C + C N CIPE C+ +DC + +DE S+ TC +F+C
Sbjct: 3129 DEDPVLCATHQCENHQWQCANKRCIPESWQCDGEDDCGDQSDEDPAHCSSRTCRPGQFKC 3188
Query: 6405 QSGACIPSKARCNHMQDCNDASDE-----IGCPFRNCSALNEFGMTGLINCATTSQCIHP 6241
++G CIP +C+ DC D SDE +G +R C EF +C T +C+ P
Sbjct: 3189 RNGRCIPQSWKCDVDNDCGDNSDEPLEECMGPAYR-CDNHTEF------SCRTNYRCV-P 3240
Query: 6240 SWK-CDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDG 6064
W C+G NDC D SDE+ C +CD F C R C+P W+CDG
Sbjct: 3241 MWSVCNGHNDCRDDSDEQGC------------DELTCDPTGDFRCNNHR-CIPLRWRCDG 3287
Query: 6063 QPDCADGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSK 5884
DC D SDE++C + CT E+ C+ + +CIP CD DC D DE CE
Sbjct: 3288 DDDCGDNSDERSCTPRTCTESEYRCD-NLRCIPNRWVCDHDNDCEDNSDERDCELRTCHP 3346
Query: 5883 GGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCAD---ET 5713
G F+CT+ CI ++CDG DC+D +DE C T F + C E
Sbjct: 3347 G---YFQCTSGHCISERFKCDGNPDCLDY-----TDETSCP---TRFPNGTYCPPFMFEC 3395
Query: 5712 CVVACELTAVLCDGIQDCSDGFDEKNCASLDRQCK-PNEWMCDSGQCIDSGRLCDASVDC 5536
C CDG DC D DE+ +D QC+ P + CD+ +CI S LC++ DC
Sbjct: 3396 KNHVCVQPHWKCDGDDDCGDNSDEELHLCIDIQCETPFRFRCDNNRCIYSHELCNSVNDC 3455
Query: 5535 VDGSDEWVEICSLSEP-PRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDN 5359
DGSDE E C + P P G + +NG C+ CD DC DE +
Sbjct: 3456 GDGSDEIPENCERNSPNPTHGPCTDEEYKCSNG--HCIPLPYACDDYDDCGDQSDELGCH 3513
Query: 5358 PQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCP-KANCSHFCI 5182
+ + N C+ R G CSC GY +K C C C C
Sbjct: 3514 RGSTHTCSDNICEHNCTDLREGGL-LCSCRPGYKPRATEKHMCEDVNECEVYGTCPQECK 3572
Query: 5181 DRRDVGHQCFCAPGYIL--SENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSN 5008
+ + +CFCA G++ + +C +L+ R++ F + + + N
Sbjct: 3573 NTKG-SFECFCAKGFVSIGEPHGTECAAQGN-PPVLLLPDNVRIRRFNLSSQQYSDYVDN 3630
Query: 5007 LTNGVALD--------------------------------YDVKSDLVYWTDVAHDGNKA 4924
+ ALD Y + +VYWT V G++
Sbjct: 3631 AEHIQALDYLWDPEGQGLSKMSACMPLHRYRLGLSYCCFLYGCAAGVVYWT-VLGRGSEF 3689
Query: 4923 GITSMSNQPNTYRVINSLPTKGI----------DGIAVDWLGRNIYYTDRNHDAIAVCDM 4774
G + P T+ S P K + DGIA+DW+GR+IY+TD + I V +
Sbjct: 3690 GSIKCAYMP-TFNDYGSNPVKEVDLNLRYVSKPDGIALDWVGRHIYWTDSGTNRIEVAKL 3748
Query: 4773 RGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIR 4594
GR+ + L+ T L+ P AI ++PL +++WTDWG I MDG N + +L D +
Sbjct: 3749 DGRYRKWLIH-TDLDQPAAIAVNPLLRMMYWTDWGRKPRIETAWMDGQN-RAVLVDEDLG 3806
Query: 4593 WPNALAVD-APAQRLYFGDAHRDYIASCNYDGSKRRMVLRG------------------- 4474
WP L VD R+Y+ D+ + + S DG+ R+ V+ G
Sbjct: 3807 WPTGLTVDYLNGNRIYWCDSKENTVESMKPDGTDRKAVISGGQSSALSGFSKLQKETPHM 3866
Query: 4473 -------SVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIV 4315
+ H ++L VFE ++YW+ + R +K G KV + +
Sbjct: 3867 HLVSTFSDIGHPYSLDVFEGHLYWTTKDTGEVWRTNKF-GNGHKVKV----------LTI 3915
Query: 4314 HPSLQSMGSLKTARHPCSQPARCDNLCIPANTPDLTTSSDNFTCMCAQG 4168
+P L + + RH + P C N+C + +TC C QG
Sbjct: 3916 NPWLTQVRVYQEHRHNQTVPNPCKNVC----SHLCLLRPGGYTCACPQG 3960
Score = 348 bits (894), Expect = 8e-94
Identities = 323/1222 (26%), Positives = 494/1222 (39%), Gaps = 72/1222 (5%)
Frame = -1
Query: 5208 KANCSHFCI-----DRRDVGHQCFCAPGYILSENQKDCR--RNDTIEAEILMVYGHRLKL 5050
+ C H C+ D +G++C C GY L + K C R+ + + L V G L
Sbjct: 200 RGGCEHICVLSHQSDNGGLGYRCKCRMGYDLHADGKHCFAVRHFLLFSSQLAVRGIPFNL 259
Query: 5049 FTIDGHAKATLLSNLTNG----VALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRV 4882
++ ++ +T + +D+ + D+++++D A D I V
Sbjct: 260 -----SSQEDIILPVTGSPSYFIGVDFSAEDDVIFFSDTAKDM----IFKQKVDGTGREV 310
Query: 4881 INSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDP 4702
+ + G++ +A DW+ +N+Y+TD + +I+V + + R +++ LN+PRAIV+ P
Sbjct: 311 LTANRVDGVEDLAYDWISKNLYWTDPRYRSISVMKVADKSRRAIVRN--LNNPRAIVVHP 368
Query: 4701 LQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYI 4522
L +FWTDW A I R DGS+ I+ + T+ WPN LA+D A RLY+ DA D I
Sbjct: 369 LIGYIFWTDWYRPAKIMRAWGDGSHALSIV-NTTLGWPNGLAIDWNAMRLYWVDAFFDKI 427
Query: 4521 ASCNYDGSKRRMVLR-GSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDK 4345
N+DG R + R + H F L +FE Y Y++DW I RV K G ++ +
Sbjct: 428 EHSNFDGQNRISLDRITQISHPFGLTIFEGYAYYTDWRLGGIVRVRKTDGGEMVIIRRGI 487
Query: 4344 QYRPMGFKIVHPSLQSMGSLKTARHPCSQPAR----CDNLCIPANTPDLTTSSDNFTCMC 4177
+ I+H S S +T + C++ C + C P PD C C
Sbjct: 488 SH------IMHVKSFSSTS-QTGFNLCNRLTNPNGDCSHFCFP--VPD-----SQRVCGC 533
Query: 4176 AQGFRSEGRSCVSECKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPC 3997
G + PN C + P C
Sbjct: 534 PYGMK---------LLPNQRTCVED-------------------------PSNEPPTLQC 559
Query: 3996 IAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKC 3817
A F CG +C+ S CDGV DC DE N C+ F C + +C
Sbjct: 560 GANSFSCG------NGKCVPNSYRCDGVDDCHDNSDEVDCGVNNSTCSPTAFTCAN-TRC 612
Query: 3816 IPLTSVCDKEKDCDDGSDELNCEIT---SCKPDFFACFNGTAISKCIPKEFYCDGEDDCP 3646
+P CD DC D SDE +C +C + F C N +C+P + CD ++DC
Sbjct: 613 VPAAWRCDGHNDCFDNSDESSCPAPAPGTCPANQFTCSN----HRCVPHSWRCDTDNDCG 668
Query: 3645 EGQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQCDGTLDCRDGSDEKGCKKECA-----I 3481
+G DE D G C QFQC +CI CDG DC DG+DE+GC C
Sbjct: 669 DGSDEADCQLG-STCHPGQFQCPDHRCIDPSYVCDGDRDCVDGADERGCIYNCTANEFKC 727
Query: 3480 VCDNSCVHADDLCDGKKKCNDGSDEDEEACVIK---QLLEKENRKC--------GGFACD 3334
+ C++ CDG C D S DE AC + + +C + CD
Sbjct: 728 ASGHQCINGYYRCDGVFDCTDRS--DERACPTRPPGMCHHESEFQCQSDGTCIPSTWECD 785
Query: 3333 GIVDCEDGSDE-KGCPDLEC----HLASN-----KSLICDGTIDCSSGKDENNCHN---N 3193
G DCED SDE CP C N +S ICDG DC DE +C
Sbjct: 786 GHPDCEDSSDEHHACPPRTCPSTFFRCDNGNCVLRSWICDGDNDCRDMSDERDCPTPPFR 845
Query: 3192 GESNFFQCSMQT--IKEWQVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCLDV 3019
S +QC + I VCD DC +G DESP +C +++ C D
Sbjct: 846 CPSWQWQCPGHSVCINLTTVCDNTPDCPNGADESP-LC--------------NQESCSDN 890
Query: 3018 STALCDGIRDCFDGSDENPIHCKDMCKGKYRCTNG--RCIDVSARXXXXXXXXXXXXXXX 2845
+ C G + P + C Y+ +N C DV
Sbjct: 891 NAG-------CTHGCIQGPFGAQCTCPVGYQLSNDSKTCGDVD----------------- 926
Query: 2844 XGAECHHFGVCAQKCWMAFNH--TARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRL 2671
EC G+C+Q C FN + RCHC GYA + D+ C+ +S + F+ +R
Sbjct: 927 ---ECSPPGICSQHC---FNERGSFRCHCQDGYA-LEADQRTCK-VSDLRQAFLLVASRN 978
Query: 2670 HLMSLE-NSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSD 2494
++ + SQ +V+ + N++ +DF T +Y R+ S SD
Sbjct: 979 QIVQDDITSQPNVVHSLVRDGRNIV--ALDFD---SVTDRVYWSDTSQDRIWSASNNGSD 1033
Query: 2493 GLIGSWGEEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIV 2314
+ + + + D++ N+Y+T+ + + V+K T L+
Sbjct: 1034 RTV-IFDSGVTVTESLAVDWVGRNLYWTDYVLE----------TVEVSKLDGTHRTVLVS 1082
Query: 2313 NSTGTINSLAVDP--IKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNI 2140
+ L +DP L+FWT PRI A++DGK +V +
Sbjct: 1083 ENVTNPRGLVLDPRSSAHLMFWTDWGRNPRIERASMDGK-----------LRTVIVNSKL 1131
Query: 2139 FEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELG-DTPVTMDVLGGYIYL 1963
+ P + +D+ N LY+ D I+ ++G +R+ V +L P + + ++Y
Sbjct: 1132 YWPNGLTIDYPNNLLYFADAYLDFIDYCDYNGNNRKQVLASDLVLQHPHAITIFEDFVYW 1191
Query: 1962 ITRQ-GSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQ----- 1801
R + R HK+ G+ N+ V P + V HPA+ + ++PC
Sbjct: 1192 TDRYINRVMRAHKWHGE-NQTVMLFNLPQPMGLVAV-HPARQPAGGNSCLRSPCSHICLL 1249
Query: 1800 --------SDYCPSNTVCVPDQ 1759
S CPS DQ
Sbjct: 1250 SAVGPAYYSCACPSGWTLAADQ 1271
Score = 179 bits (455), Expect = 6e-43
Identities = 111/338 (32%), Positives = 158/338 (45%), Gaps = 23/338 (6%)
Frame = -1
Query: 6576 FDDEDTKYC---STRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC----TCNEN 6418
FD+ D C + C F C N C+P C+ NDC + +DE++C TC+
Sbjct: 626 FDNSDESSCPAPAPGTCPANQFTCSNHRCVPHSWRCDTDNDCGDGSDEADCQLGSTCHPG 685
Query: 6417 EFRCQSGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPS 6238
+F+C CI C+ +DC D +DE GC + NC+A NEF CA+ QCI+
Sbjct: 686 QFQCPDHRCIDPSYVCDGDRDCVDGADERGCIY-NCTA-NEF------KCASGHQCINGY 737
Query: 6237 WKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQP 6058
++CDG DC D SDE+ C P C +++F C + TC+P W+CDG P
Sbjct: 738 YRCDGVFDCTDRSDERAC---------PTRPPGMCHHESEFQCQSDGTCIPSTWECDGHP 788
Query: 6057 DCADGSDEKN-CDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCET---ECD 5890
DC D SDE + C + C S F C++ C+ CDG DC D DE C T C
Sbjct: 789 DCEDSSDEHHACPPRTCPSTFFRCDNG-NCVLRSWICDGDNDCRDMSDERDCPTPPFRCP 847
Query: 5889 SKGGNATFRCTNHR-CIPMAWRCDGTDDC--------MDNAKSLGSDEVDCAAGRTSFHV 5737
S ++C H CI + CD T DC + N +S + C G
Sbjct: 848 S----WQWQCPGHSVCINLTTVCDNTPDCPNGADESPLCNQESCSDNNAGCTHGCIQGPF 903
Query: 5736 PSRCADETCVVACELT--AVLCDGIQDCS-DGFDEKNC 5632
++C TC V +L+ + C + +CS G ++C
Sbjct: 904 GAQC---TCPVGYQLSNDSKTCGDVDECSPPGICSQHC 938
Score = 168 bits (426), Expect = 1e-39
Identities = 111/335 (33%), Positives = 146/335 (43%), Gaps = 15/335 (4%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADES-NC-----TCNENEFR 6409
DE +C C F C +G CIP + C+ DC++ +DE +C TCN +FR
Sbjct: 2400 DESPTHCVASTCSQSEFRCSSGRCIPARWYCDGGADCSDSSDEPLSCTPQVRTCNTEQFR 2459
Query: 6408 CQSGACIPSKARCNHMQDCNDASDE---IGCPFRNCSALNEFGMTGLINCATTSQCIHPS 6238
C G CI S C+ DC D SDE C R CS T + N +CI
Sbjct: 2460 CDDGRCIASTWICDGDNDCGDMSDEDQRHNCANRTCSNAE---FTCVNNQPPQRKCIPRD 2516
Query: 6237 WKCDGTNDCYDGSDE-KDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQ 6061
W CDG DC D DE ++C RSC +F C + C+ ++CD +
Sbjct: 2517 WVCDGDADCADALDEHQNC------------TRRSCGV-NEFTC-SNGLCIRSSYRCDRR 2562
Query: 6060 PDCADGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGED--EHQCETECDS 5887
DC DGSDE+ C + C +F+C++ +CI + CDG DC D D EH C T +
Sbjct: 2563 NDCGDGSDEQGCTYQACQQHQFTCQNG-RCISRDFVCDGDNDCGDESDELEHMCHTPAPT 2621
Query: 5886 KGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCV 5707
FRC N CI ++ CD DDC DN+ G +C + H C D
Sbjct: 2622 -CPPGEFRCDNGHCISLSRVCDRNDDCSDNSDEKGCGVNEC-TDPSIHHCDHSCTDTPTS 2679
Query: 5706 VACELTAVLCDGIQDCSDG---FDEKNCASLDRQC 5611
C G + SDG D CA R C
Sbjct: 2680 FICTCR----PGYRLMSDGKTCDDVNECAETPRVC 2710
Score = 145 bits (367), Expect = 1e-32
Identities = 104/324 (32%), Positives = 139/324 (42%), Gaps = 40/324 (12%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNC---TCNENEFRCQ 6403
D+ D + C+ R C + C N CIP + VC+ NDC + +DE +C TC+ F+C
Sbjct: 3293 DNSDERSCTPRTCTESEYRCDNLRCIPNRWVCDHDNDCEDNSDERDCELRTCHPGYFQCT 3352
Query: 6402 SGACIPSKARCNHMQDCNDASDEIGCP--FRNCSALNEFGMTGLINCATTSQCIHPSWKC 6229
SG CI + +C+ DC D +DE CP F N + F + C C+ P WKC
Sbjct: 3353 SGHCISERFKCDGNPDCLDYTDETSCPTRFPNGTYCPPF----MFEC-KNHVCVQPHWKC 3407
Query: 6228 DGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCA 6049
DG +DC D SDE+ + C+ +F C R C+ H C+ DC
Sbjct: 3408 DGDDDCGDNSDEE----------LHLCIDIQCETPFRFRCDNNR-CIYSHELCNSVNDCG 3456
Query: 6048 DGSDE--KNCDAKK-------CTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDE------ 5914
DGSDE +NC+ CT E+ C S+ CIPL CD DC D DE
Sbjct: 3457 DGSDEIPENCERNSPNPTHGPCTDEEYKC-SNGHCIPLPYACDDYDDCGDQSDELGCHRG 3515
Query: 5913 -------HQCETEC-DSKGGNATFRC---------TNHRCIPMAWRCDGTDDCMDNAKSL 5785
+ CE C D + G C H C + C+ C K+
Sbjct: 3516 STHTCSDNICEHNCTDLREGGLLCSCRPGYKPRATEKHMCEDVN-ECEVYGTCPQECKNT 3574
Query: 5784 -GSDEVDCAAGRTSFHVP--SRCA 5722
GS E CA G S P + CA
Sbjct: 3575 KGSFECFCAKGFVSIGEPHGTECA 3598
Score = 131 bits (329), Expect = 3e-28
Identities = 110/387 (28%), Positives = 174/387 (44%), Gaps = 18/387 (4%)
Frame = -1
Query: 5250 PYDKKTCLRSPSCPKANCSHFCIDRRDVG---HQCFCAPGYILSENQKDCRRNDT---IE 5089
P +CLRSP CSH C+ VG + C C G+ L+ +Q C R + +
Sbjct: 1232 PAGGNSCLRSP------CSHICL-LSAVGPAYYSCACPSGWTLAADQITCTRVEDPFLVV 1284
Query: 5088 AEILMVYGHRLKLFTIDGHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSM 4909
++YG L A + + L NG +D+D ++YW V H G + S
Sbjct: 1285 VRDSIIYGISLNPEDKSNDAMVPV-AGLQNGYDVDFDDNEQIIYW--VEHPGEIHSVKSD 1341
Query: 4908 SNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRG----RFNRILLKG 4741
+ L + G+A+DW+ +N+YYT+ + +I V +RG R I G
Sbjct: 1342 GTNRTEFAPAAILGSPV--GLALDWITQNLYYTNPSTQSIEVLKLRGEVQYRKTLITNNG 1399
Query: 4740 TPLN--DPRAIVLDPLQALVFWTDWGAS----AHIGRMNMDGSNEQVILQDRTIRWPNAL 4579
+P P I +DP + ++WTD G A + NMDGSN V L + L
Sbjct: 1400 SPTGAGSPVGIAVDPARGKLYWTDQGTESGIPAKVASANMDGSNP-VNLFTNNLDHIEFL 1458
Query: 4578 AVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTI 4399
VD +LY+ I S + DG+ R ++ G + H + +AV+ ++Y++D I
Sbjct: 1459 TVDIRENKLYWAVTSTGAIESGDPDGTNRITIVTG-LSHPWGVAVYGSHLYFTDRDFEVI 1517
Query: 4398 ERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDNLCIPANT 4219
ERV K TGTNR VL + G +++ + + + + C+ +C+PA
Sbjct: 1518 ERVDKTTGTNRVVLRDNVS----GLRVLKVHYRETSAGVSNGCTDNNMGACEQICLPA-- 1571
Query: 4218 PDLTTSSDNFTCMCAQGFR--SEGRSC 4144
FTC CA GF+ ++ R+C
Sbjct: 1572 -----PQGFFTCACATGFKLNTDNRTC 1593
Score = 122 bits (307), Expect = 9e-26
Identities = 81/265 (30%), Positives = 108/265 (40%), Gaps = 25/265 (9%)
Frame = -1
Query: 6579 MFDDEDTKYCSTRVCRPGYFNCGNG-----LCIPEQKVCNRINDCANFADE-SNCT---C 6427
M D++ C+ R C F C N CIP VC+ DCA+ DE NCT C
Sbjct: 2481 MSDEDQRHNCANRTCSNAEFTCVNNQPPQRKCIPRDWVCDGDADCADALDEHQNCTRRSC 2540
Query: 6426 NENEFRCQSGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCI 6247
NEF C +G CI S RC+ DC D SDE GC ++ C ++F +CI
Sbjct: 2541 GVNEFTCSNGLCIRSSYRCDRRNDCGDGSDEQGCTYQACQQ-HQF-------TCQNGRCI 2592
Query: 6246 HPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCD 6067
+ CDG NDC D SDE + P +F C C+ CD
Sbjct: 2593 SRDFVCDGDNDCGDESDELEHMCH---------TPAPTCPPGEFRC-DNGHCISLSRVCD 2642
Query: 6066 GQPDCADGSDEKNCDAKKC----------------TSFEFSCESSKKCIPLEQKCDGRRD 5935
DC+D SDEK C +C TSF +C + + + CD +
Sbjct: 2643 RNDDCSDNSDEKGCGVNECTDPSIHHCDHSCTDTPTSFICTCRPGYRLMSDGKTCDDVNE 2702
Query: 5934 CPDGEDEHQCETECDSKGGNATFRC 5860
C E C C++ G+ +C
Sbjct: 2703 C--AETPRVCSQVCENTVGSYVCKC 2725
Score = 114 bits (285), Expect = 3e-23
Identities = 92/366 (25%), Positives = 162/366 (44%), Gaps = 13/366 (3%)
Frame = -1
Query: 5199 CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGH---- 5032
C C+ C CA G+ L+ + + C ++ +++ +K F+++G
Sbjct: 1564 CEQICLPAPQGFFTCACATGFKLNTDNRTCA---PYQSYVVISTLSAIKGFSLEGEDHSE 1620
Query: 5031 AKATLLSNLTNGVALDYDVKSDLVYWTDVAHD-GNKAGITSMSNQPNTYR--VINSLPTK 4861
A + N + +D + S +YW D + + G+ + + R V + +
Sbjct: 1621 AMVPVAGRGRNALHIDVHMASGFIYWCDFSSTVAAQNGVRRIKPDGSGLRSIVTSGIGRN 1680
Query: 4860 GIDGIAVDWLGRNIYYTDR--NHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALV 4687
GI GIAVDW N+Y+T+ + V + F R+LLK T ++ PR IV+DP + +
Sbjct: 1681 GIRGIAVDWAAGNLYFTNAFLTETYVEVLRLNTTFRRVLLK-TQVDMPRHIVVDPRRRYL 1739
Query: 4686 FWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNY 4507
FW D+G I R +DG+N +++ + P LA+D + +Y+ D D IA +
Sbjct: 1740 FWADYGQHPKIERALLDGTNRTILVSSGIVT-PRGLALDWQSGYVYWVDDSLDMIARVSP 1798
Query: 4506 DGSKRRMVLRGS-VRHIFALAVFEDYVYWSDWHNHTIERVHKITG-TNRKVLIQDKQYRP 4333
G + +V GS + + VFE+ + W D + + R K G T + +I+D
Sbjct: 1799 QGGETEVVRYGSRYPTPYGITVFENSIIWVDRNLKKVFRASKEPGSTEQPTVIRDNINML 1858
Query: 4332 MGFKIVHPSLQSMGSLKTARHPC-SQPARCDNLCIPANTPDLTTSSDNFTCMCAQG-FRS 4159
I Q + + +PC + C + C P+ + N C CA G +
Sbjct: 1859 RDVTIFDRHTQPTTAQELNFNPCVEENGGCAHFCFA--LPEYGSDGQNKVCSCAFGNLGA 1916
Query: 4158 EGRSCV 4141
+ + CV
Sbjct: 1917 DNKGCV 1922
Score = 110 bits (276), Expect = 4e-22
Identities = 74/271 (27%), Positives = 131/271 (48%), Gaps = 12/271 (4%)
Frame = -1
Query: 4920 ITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKG 4741
+ S+ + +V+ ++ + +AVDW+ +Y + + + I V D G NR+ L
Sbjct: 2 VFSVDMDGSNVQVVLNVSVDYPENLAVDWVNNKLYVVEASVNRIDVVDFDGS-NRVTLIT 60
Query: 4740 TPLNDPRAIVLDPLQALVFWTDWGA---SAHIGRMNMDGSNEQVILQDRTIRWPNALAVD 4570
L +PR + +DP +F+TDW A + R MDG+N I+ + + WP+ + +D
Sbjct: 61 ENLGNPRGVAVDPTVGYMFFTDWEAINGQPGLERAFMDGTNRYGIIGTK-LGWPSGITLD 119
Query: 4569 APAQRLYFGDAHRDYIASCNYDGSKRRMVLRGS--VRHIFALAVFEDYVYWSDWHNHTIE 4396
A+R+Y+ D+ DYI + YDG R+ V+ G V H F +++FE VY++DW +
Sbjct: 120 IEAKRIYWVDSRYDYIETATYDGVHRKTVVHGGAVVPHPFGISLFEHSVYFTDWTKMAVM 179
Query: 4395 RVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPC-SQPARCDNLCIPANT 4219
R +K T ++ PS+Q +PC + C+++C+
Sbjct: 180 RANKFTDSS------------------PPSVQ---------NPCGTNRGGCEHICV---- 208
Query: 4218 PDLTTSSDN----FTCMCAQGF--RSEGRSC 4144
L+ SDN + C C G+ ++G+ C
Sbjct: 209 --LSHQSDNGGLGYRCKCRMGYDLHADGKHC 237
Score = 95.5 bits (236), Expect = 2e-17
Identities = 182/859 (21%), Positives = 295/859 (34%), Gaps = 57/859 (6%)
Frame = -1
Query: 2775 RCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLE---NSQVSVLRPVFNIKMN 2605
RC C GY D C + F+ ++L + + +SQ ++ PV
Sbjct: 221 RCKCRMGYD-LHADGKHCF----AVRHFLLFSSQLAVRGIPFNLSSQEDIILPVTGSPSY 275
Query: 2604 LIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGLI------T 2443
I G+DF + + ++ D+ K+ DG G E TA +
Sbjct: 276 FI--GVDFSAEDD------VIFFSDTAKDMIFKQKVDGT----GREVLTANRVDGVEDLA 323
Query: 2442 YDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRL 2263
YD++ N+Y+T+ R +I V K D S R ++ N ++ V P+
Sbjct: 324 YDWISKNLYWTDP----------RYRSISVMKVADKSRRAIVRNLNNP-RAIVVHPLIGY 372
Query: 2262 IFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWID 2083
IFWT +I+ A DG ++V + P + +D++ RLYW+D
Sbjct: 373 IFWTDWYRPAKIMRAWGDGSHAL-----------SIVNTTLGWPNGLAIDWNAMRLYWVD 421
Query: 2082 VLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGKTNK 1906
IE +FDG++R ++ + P + + GY Y R G I R+ K G
Sbjct: 422 AFFDKIEHSNFDGQNRISLDRITQISHPFGLTIFEGYAYYTDWRLGGIVRVRKTDGGEMV 481
Query: 1905 YVQKIREVSPRIQIRVAHPAKHTVSHITHQK---NPCQSDYCPSNTVCVPDQDKNGILIP 1735
+++ +SHI H K + Q+ + N + P+ D + P
Sbjct: 482 IIRR------------------GISHIMHVKSFSSTSQTGFNLCNRLTNPNGDCSHFCFP 523
Query: 1734 ------KCLCGPGRFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCSPQKTCVCPPGFY 1573
C C G + + C++ + QCG N+ C K C P Y
Sbjct: 524 VPDSQRVCGCPYGMKLLPNQRTCVEDPSNEPPTLQCG----ANSFSCGNGK---CVPNSY 576
Query: 1572 GRQCE-INECSETC------WNGETCAVQEFGSTTNVVCHCPSNYT---QSSCATNVCEG 1423
+C+ +++C + N TC+ F + N C P+ + + C N E
Sbjct: 577 --RCDGVDDCHDNSDEVDCGVNNSTCSPTAF-TCANTRC-VPAAWRCDGHNDCFDNSDES 632
Query: 1422 VCGPRGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHKADAKVCYGHCFSGGACDGEG 1243
C P + T CP ++ C ++ C H + CD +
Sbjct: 633 SC-PAPAPGT--CPANQFTCSNHR---------------------CVPHSW---RCDTDN 665
Query: 1242 PLNLRCSCGDGLTGNRCQ----------NCVGHECLNGGFCSYANSNRSLPHCICPSGFT 1093
CGDG CQ C H C++ + + + C G
Sbjct: 666 ------DCGDGSDEADCQLGSTCHPGQFQCPDHRCIDPSYVCDGDRD-------CVDGAD 712
Query: 1092 GDHCEEYLC---KDACPFGSKCTYDITKPMDPITCSCEQNAAAHNTDCSPICQKQPNW-C 925
C Y C + C G +C + C+ + A T +C + + C
Sbjct: 713 ERGC-IYNCTANEFKCASGHQCINGYYRCDGVFDCTDRSDERACPTRPPGMCHHESEFQC 771
Query: 924 HNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSKC--TITNGTHFECD---C 760
+ G C+ + CD C+D + C T F CD C
Sbjct: 772 QSDGTCIPSTW--------------ECDGHPDCEDSSDEHHACPPRTCPSTFFRCDNGNC 817
Query: 759 KPGFKGLRCEQETKCSECSNEAKCIKKPSGTVIC-----QCPQGLGGEYCEKITATSCHQ 595
+ C+ + C + S+E C P+ C QCP G C +T +
Sbjct: 818 V--LRSWICDGDNDCRDMSDERDC---PTPPFRCPSWQWQCP---GHSVCINLTTVCDNT 869
Query: 594 LECKNGG----YCLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCLHDGNCTLDEYFE 427
+C NG C + S N T C G G C+ C +
Sbjct: 870 PDCPNGADESPLCNQESCSDNNAGCTHGCIQGPFGAQCTCPVGYQLSNDSKTCGDVDECS 929
Query: 426 PQCECYQAFIGDRCQYRIH 370
P C Q +R +R H
Sbjct: 930 PPGICSQHCFNERGSFRCH 948
Score = 88.6 bits (218), Expect = 2e-15
Identities = 176/856 (20%), Positives = 287/856 (32%), Gaps = 80/856 (9%)
Frame = -1
Query: 2772 CHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQVSVLRPVFNIKMNLIPG 2593
C CA G +N+ +S+ + T + + + L+ ++ PV N+ +
Sbjct: 1907 CSCAFG---NLGADNKGCVVSRDDYLIYTTESTVRSLRLDPDDHALPFPVVNVPRTSV-- 1961
Query: 2592 GIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGLITYDFMHNNVYF 2413
+DF R + G G S++ S + I YD+++ +Y+
Sbjct: 1962 ALDFDLTERRIYFTQSSGAGASKISYVSLSAPTSTPVVVAFDLGAPDGIAYDWINRRIYY 2021
Query: 2412 TESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVP 2233
++ Q+ + + + S RT++V+ + ++ +DP + ++WT
Sbjct: 2022 SDFVNQSINSM-----------SVEGSQRTVVVHVSRP-RAIMLDPCRGYMYWTDWGTHA 2069
Query: 2232 RILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVS 2053
+I A L G F+T +V ++ P + LD+ +ERLYW D + IE S
Sbjct: 2070 KIERATLGGN-----FRTD------IVNSSLVWPNGLTLDYEDERLYWADASLQKIERSS 2118
Query: 2052 FDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGKTNKYV-------- 1900
G DR + + P M + +IY SI+R +K G + +
Sbjct: 2119 LTGSDREVIVSTAI--YPFAMTMFDQFIYWTDWNTRSIYRANKHDGSGQRVMIQNLPSRP 2176
Query: 1899 QKIREVSPRIQIRVAHPAKHTVSHITHQKNP--------CQSD---YCPSNTVCVPDQDK 1753
I ++ R Q + P + +H P C S+ Y + C+PD
Sbjct: 2177 MDIHVLASRKQQQCDSPCQQFNGGCSHICTPGPNGAECHCPSEGRWYLADSKHCIPD--- 2233
Query: 1752 NGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCSPQKTC------V 1591
NG C PG+ F C++ + K + CGD C P+
Sbjct: 2234 NG-----TRCQPGQ-FTCMNGHCIRAQWKCDNENDCGDGSDELERVCGPKPKFTIVAFHT 2287
Query: 1590 CPPGFYGRQCEINECSETCWNGETCAVQEFGSTTNVVCHCPSNYTQSSCATNVCEGVCGP 1411
C P + TC NG C + + C N + C C+
Sbjct: 2288 CEPTVF-----------TCGNGR-CVPYHY--RCDHYDDCGDNSDELGCLFRPCDP--SR 2331
Query: 1410 RGSCKTVPCPKDEPHCRSYSFC---------ECDKGWTGPHCRHKADAKVCYGHCFSGGA 1258
+C C + C + C C + P +C +
Sbjct: 2332 EFTCNNGRCIAKDYVCNGINNCYDNGTSDEQNCPERTCQPEQTKCQSTNICIPRSY---L 2388
Query: 1257 CDGEGPLNLRCSCGDGLTGNRCQNCVGHECLNGGF-CSYANSNRSLP-HCICPSGFTGDH 1084
CDG+ CGD ++ +CV C F CS S R +P C G
Sbjct: 2389 CDGDN------DCGD-MSDESPTHCVASTCSQSEFRCS---SGRCIPARWYCDGGAD--- 2435
Query: 1083 CEEYLCKDACPFGSKCTYDITKPMDPITCSCEQNAAAH------------NTDCSPIC-Q 943
C D+ CT + TC+ EQ + DC + +
Sbjct: 2436 -----CSDSSDEPLSCTPQVR------TCNTEQFRCDDGRCIASTWICDGDNDCGDMSDE 2484
Query: 942 KQPNWCHN----GGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNNSKCTITNGTH 775
Q + C N P + KC+PR CD C D + CT +
Sbjct: 2485 DQRHNCANRTCSNAEFTCVNNQPPQRKCIPR--DWVCDGDADCADALDEHQNCTRRSCGV 2542
Query: 774 FECDCKPGF---KGLRCEQETKCSECSNEAKCIKKP--------------SGTVICQCPQ 646
E C G RC++ C + S+E C + S +C
Sbjct: 2543 NEFTCSNGLCIRSSYRCDRRNDCGDGSDEQGCTYQACQQHQFTCQNGRCISRDFVCDGDN 2602
Query: 645 GLGGEYCE-----KITATSC--HQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSS 487
G E E A +C + C N G+C+ +R CS C
Sbjct: 2603 DCGDESDELEHMCHTPAPTCPPGEFRCDN-GHCISLSRVCDRNDD---CSDNSDEKGCGV 2658
Query: 486 NACENFCLH--DGNCT 445
N C + +H D +CT
Sbjct: 2659 NECTDPSIHHCDHSCT 2674
Score = 80.1 bits (196), Expect = 7e-13
Identities = 75/292 (25%), Positives = 101/292 (33%), Gaps = 74/292 (25%)
Frame = -1
Query: 5916 EHQCETECDSKGGNAT----------------------------------------FRCT 5857
+ QC++ C G + F C
Sbjct: 2187 QQQCDSPCQQFNGGCSHICTPGPNGAECHCPSEGRWYLADSKHCIPDNGTRCQPGQFTCM 2246
Query: 5856 NHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAG-RTSFHVPSRCADETCVVACELTAVL 5680
N CI W+CD +DC D GSDE++ G + F + + E V C +
Sbjct: 2247 NGHCIRAQWKCDNENDCGD-----GSDELERVCGPKPKFTIVAFHTCEPTVFTCGNGRCV 2301
Query: 5679 -----CDGIQDCSDGFDEKNCASLDRQCKPN-EWMCDSGQCIDSGRLCDASVDCVDGSDE 5518
CD DC D DE C L R C P+ E+ C++G+CI +C+ +C D
Sbjct: 2302 PYHYRCDHYDDCGDNSDELGC--LFRPCDPSREFTCNNGRCIAKDYVCNGINNCYDNGTS 2359
Query: 5517 WVEICSLSEPPRRGC-PSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQ--------C 5365
+ C P R C P C TN C+ LCDG DC DE C
Sbjct: 2360 DEQNC-----PERTCQPEQTKCQSTN---ICIPRSYLCDGDNDCGDMSDESPTHCVASTC 2411
Query: 5364 DNPQGNCSSTR---------------NSCDQTWNCQ---RHAGFESCSCDDG 5263
+ CSS R +S D+ +C R E CDDG
Sbjct: 2412 SQSEFRCSSGRCIPARWYCDGGADCSDSSDEPLSCTPQVRTCNTEQFRCDDG 2463
Score = 60.1 bits (144), Expect = 7e-07
Identities = 77/324 (23%), Positives = 118/324 (35%), Gaps = 16/324 (4%)
Frame = -1
Query: 2829 HHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLEN 2650
++ G C Q C A C CA G+ + D C P + + I+ + + SLE
Sbjct: 1559 NNMGACEQICLPAPQGFFTCACATGF-KLNTDNRTCAPYQ--SYVVISTLSAIKGFSLEG 1615
Query: 2649 SQVSVL--------RPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSD 2494
S R +I +++ G I + D F +T+ G+ + D
Sbjct: 1616 EDHSEAMVPVAGRGRNALHIDVHMASGFI-YWCD-FSSTVAAQNGVRRIKPD-------- 1665
Query: 2493 GLIGSWGEEESTAGL-------ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDT 2335
GS T+G+ I D+ N+YFT + F + + V + T
Sbjct: 1666 ---GSGLRSIVTSGIGRNGIRGIAVDWAAGNLYFTNA--------FLTETYVEVLRLNTT 1714
Query: 2334 STRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKAL 2155
R L+ + VDP +R +FW P+I A LDG L
Sbjct: 1715 FRRVLLKTQVDMPRHIVVDPRRRYLFWADYGQHPKIERALLDG-----------TNRTIL 1763
Query: 2154 VERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGG 1975
V I P + LD+ + +YW+D I VS G + VR TP + V
Sbjct: 1764 VSSGIVTPRGLALDWQSGYVYWVDDSLDMIARVSPQGGETEVVRYGSRYPTPYGITVFEN 1823
Query: 1974 YIYLITRQ-GSIHRMHKFTGKTNK 1906
I + R + R K G T +
Sbjct: 1824 SIIWVDRNLKKVFRASKEPGSTEQ 1847
Score = 59.7 bits (143), Expect = 9e-07
Identities = 101/423 (23%), Positives = 147/423 (33%), Gaps = 49/423 (11%)
Frame = -1
Query: 1821 HQKNPCQSDY--------CPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQLREK 1666
H + C+++Y C + C D D+ G + C P F + +C+ LR +
Sbjct: 3227 HTEFSCRTNYRCVPMWSVCNGHNDCRDDSDEQGC--DELTCDPTGDFRCNNHRCIPLRWR 3284
Query: 1665 DQEASQCGD----------------YFCYNNAGCSPQKTCV-----CPPGFYGRQCEINE 1549
CGD Y C +N C P + C R CE+
Sbjct: 3285 CDGDDDCGDNSDERSCTPRTCTESEYRC-DNLRCIPNRWVCDHDNDCEDNSDERDCELRT 3343
Query: 1548 CSE---TCWNGETCAVQEFGSTTNVVCHCPSNYT-QSSCATNVCEGV-CGP-RGSCKTVP 1387
C C +G C + F N C +YT ++SC T G C P CK
Sbjct: 3344 CHPGYFQCTSGH-CISERFKCDGNPDC---LDYTDETSCPTRFPNGTYCPPFMFECKNHV 3399
Query: 1386 CPKDEPHCRSYSFCECDKGWTGPHCRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGL 1207
C +PH + C+ D C +D ++ H C E P RC +
Sbjct: 3400 CV--QPHWK----CDGDDD-----CGDNSDEEL---HLCIDIQC--ETPFRFRCDNNRCI 3443
Query: 1206 TGNRCQNCVGHECLNGGFCSYANSNRSLP---HCICPSGFTGDHCEEYLCKDA----CPF 1048
+ N V ++C +G N R+ P H C EEY C + P+
Sbjct: 3444 YSHELCNSV-NDCGDGSDEIPENCERNSPNPTHGPCTD-------EEYKCSNGHCIPLPY 3495
Query: 1047 GSKCTYDITKPMDPITC------SCEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYP 886
D D + C +C N HN C+ + + G C PGY
Sbjct: 3496 ACDDYDDCGDQSDELGCHRGSTHTCSDNICEHN--CTDLRE-------GGLLCSCRPGYK 3546
Query: 885 GKCKCLPRFAGPR-CDVPVQCDDYCTNNSKCTITNGTHFECDCKPGFKGLRCEQETKCSE 709
PR C+ +C+ Y T +C T G+ FEC C GF + T+C+
Sbjct: 3547 ------PRATEKHMCEDVNECEVYGTCPQECKNTKGS-FECFCAKGFVSIGEPHGTECAA 3599
Query: 708 CSN 700
N
Sbjct: 3600 QGN 3602
Score = 54.3 bits (129), Expect = 4e-05
Identities = 60/264 (22%), Positives = 104/264 (38%), Gaps = 5/264 (1%)
Frame = -1
Query: 2448 ITYDFMHNNVYFTESSEQNRGVL-FDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPI 2272
+ D+++N +Y E+S V+ FD + TLI + G +AVDP
Sbjct: 26 LAVDWVNNKLYVVEASVNRIDVVDFDGSNRV-----------TLITENLGNPRGVAVDPT 74
Query: 2271 KRLIFWTTSAPVPRILSANLDGKP-IAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERL 2095
+F+T + +G+P + + F G+ + ++ + P+ + LD +R+
Sbjct: 75 VGYMFFTDWEAI--------NGQPGLERAFMDGTNRY-GIIGTKLGWPSGITLDIEAKRI 125
Query: 2094 YWIDVLKRTIETVSFDGRDRRT-VRKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFT 1921
YW+D IET ++DG R+T V + P + + +Y + ++ R +KFT
Sbjct: 126 YWVDSRYDYIETATYDGVHRKTVVHGGAVVPHPFGISLFEHSVYFTDWTKMAVMRANKFT 185
Query: 1920 GKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVCV-PDQDKNGI 1744
+ VQ NPC ++ +CV Q NG
Sbjct: 186 DSSPPSVQ----------------------------NPCGTNRGGCEHICVLSHQSDNGG 217
Query: 1743 LIPKCLCGPGRFFEVSTKKCMQLR 1672
L +C C G K C +R
Sbjct: 218 LGYRCKCRMGYDLHADGKHCFAVR 241
Score = 50.4 bits (119), Expect = 6e-04
Identities = 55/193 (28%), Positives = 85/193 (43%), Gaps = 10/193 (5%)
Frame = -1
Query: 2448 ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNS-----TGTINSLA 2284
+ D++ N+Y+T S Q+ VL R Y +TLI N+ G+ +A
Sbjct: 1360 LALDWITQNLYYTNPSTQSIEVLKLRGEVQY--------RKTLITNNGSPTGAGSPVGIA 1411
Query: 2283 VDPIKRLIFWT---TSAPVP-RILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVL 2116
VDP + ++WT T + +P ++ SAN+D GS P L N+ + +
Sbjct: 1412 VDPARGKLYWTDQGTESGIPAKVASANMD----------GSNPVN-LFTNNLDHIEFLTV 1460
Query: 2115 DFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITRQGS-IH 1939
D +LYW IE+ DG +R T+ P + V G ++Y R I
Sbjct: 1461 DIRENKLYWAVTSTGAIESGDPDGTNRITI--VTGLSHPWGVAVYGSHLYFTDRDFEVIE 1518
Query: 1938 RMHKFTGKTNKYV 1900
R+ K TG TN+ V
Sbjct: 1519 RVDKTTG-TNRVV 1530
Score = 38.1 bits (87), Expect = 2.9
Identities = 34/131 (25%), Positives = 46/131 (34%), Gaps = 2/131 (1%)
Frame = -1
Query: 1464 NYTQSSCATNVCEGVCGPRGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHKADAKVC 1285
N T + NVC +C R T CP+ SF E D G
Sbjct: 3931 NQTVPNPCKNVCSHLCLLRPGGYTCACPQGS------SFAESDFG--------------- 3969
Query: 1284 YGHCFSGGACDG--EGPLNLRCSCGDGLTGNRCQNCVGHECLNGGFCSYANSNRSLPHCI 1111
CD E P+ + +C C+NGG C Y + +P C
Sbjct: 3970 --------ICDAAIEPPVTMPPAC---------------RCMNGGTC-YTDEG-GMPKCK 4004
Query: 1110 CPSGFTGDHCE 1078
CP G+TG +C+
Sbjct: 4005 CPYGYTGSYCD 4015
Score = 36.6 bits (83), Expect = 8.5
Identities = 28/116 (24%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Frame = -1
Query: 2232 RILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVS 2053
++ S ++DG + + ++ ++ P ++ +D+ N +LY ++ I+ V
Sbjct: 1 QVFSVDMDGSNV-----------QVVLNVSVDYPENLAVDWVNNKLYVVEASVNRIDVVD 49
Query: 2052 FDGRDRRTVRKFELGD-TPVTMDVLGGYIYL-----ITRQGSIHRMHKFTGKTNKY 1903
FDG +R T+ LG+ V +D GY++ I Q + R F TN+Y
Sbjct: 50 FDGSNRVTLITENLGNPRGVAVDPTVGYMFFTDWEAINGQPGLER--AFMDGTNRY 103
>gi|24640820|ref|NP_572563.2| CG12139-PB [Drosophila melanogaster]
gi|7291057|gb|AAF46494.1| CG12139-PB [Drosophila melanogaster]
Length = 4547
Score = 659 bits (1701), Expect = 0.0
Identities = 531/1818 (29%), Positives = 775/1818 (42%), Gaps = 147/1818 (8%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCT---CNENEFRCQS 6400
DED YC+ C P F C NG CI + C+ NDC + +DE C C + EF C +
Sbjct: 2634 DEDPNYCAYHSCSPNEFRCNNGRCIFKSWKCDHENDCKDGSDELGCVYPPCVDGEFTCAN 2693
Query: 6399 GACIPSKARCNHMQDCND--ASDEIG--CPFRNCSALNEFGMTGLINCATTSQCIHPSWK 6232
G CIP CN + DC D SDE CP N + C T+ C+ P W
Sbjct: 2694 GRCIPQAQVCNGVNDCKDNATSDETHERCPMNTTCPANH------LKCEKTNICVEPYWL 2747
Query: 6231 CDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDC 6052
CDG NDC D SDE R+C + F C R C+P W CDG DC
Sbjct: 2748 CDGDNDCGDNSDEDPLHC----------GQRTCPTNS-FRCPNHR-CIPATWYCDGDDDC 2795
Query: 6051 ADGSDEK----NCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDE---HQC-ETE 5896
DG+DE + + C F+C++ CIP CDG DC D DE HQC + +
Sbjct: 2796 GDGADEPPDYCKSEGRTCFGDLFTCDNGN-CIPRIYICDGDNDCLDNSDEDNRHQCNDRK 2854
Query: 5895 CDSKGGNATFRCTNHR------CIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVP 5734
CD + F C ++ CIP W CDG DC+D A + +CA +
Sbjct: 2855 CDEE---TEFTCVENKSWQRAQCIPKKWICDGDPDCVDGADE-NTTLHNCATQQPCGEDM 2910
Query: 5733 SRCADETCVVACELTAVLCDGIQDCSDGFDE-KNCASLDRQCKPNEWMCDSGQCIDSGRL 5557
C + C+ +CD DC DG DE K C S + C E+ C + +CI +
Sbjct: 2911 FTCGNGRCINK----GWICDHDNDCGDGTDEGKFCNSKYKTCSAQEFTCQNFKCIRNQSR 2966
Query: 5556 CDASVDCVDGSDEWVEICSLSEPPRRGCPSG-WSCLLTNGTIGCLQEQQLCDGRRDCMSG 5380
CD DC D SDE C+ CP G ++C TNG C+ +C+ DC
Sbjct: 2967 CDGEDDCGDHSDEVG--CAKENIT---CPQGQFAC--TNGQ--CIDYNLVCNKYPDCADE 3017
Query: 5379 IDEQCDNPQGNCSSTR-NSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPK- 5206
DE C+ N C C C C++GY L D K C C +
Sbjct: 3018 SDEPAHCNVDECAKVEINQCGH--KCVDTLTGYYCDCNEGYKLLA-DGKACADVDECLEQ 3074
Query: 5205 -ANCSHFCIDRRDVGHQCFCAPGYILSENQKD-CRRNDTIEAEILMVYGHRLKLFTIDGH 5032
CS C + G C C Y +N + C+R D I ++ + ++ ++DGH
Sbjct: 3075 PGACSQHCSNTPG-GFYCKCDETYYERQNDEHTCKRKDKIPPWLIFTNKYYVRNMSVDGH 3133
Query: 5031 AKATLLSNLTNGVALDYDVKSDLVYWTDVAHDG---NKAGITSMSNQPNTYRVINSLPTK 4861
+ +L N VALD+D++ + +Y+ DV K G P VI +
Sbjct: 3134 QYNLMHQDLMNVVALDFDIREEYMYFCDVTAKTIFRAKYGEADDEMPPEREAVIRH-DSH 3192
Query: 4860 GIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFW 4681
G++GIA+DW+GR +Y+ DR+ + V ++ G + L G DPRAIV+ P +++
Sbjct: 3193 GLEGIAIDWVGRKLYWLDRHSKNLDVSELDGSKRKTLRSGVV--DPRAIVVHPGIGYLYF 3250
Query: 4680 TDWGASAHIGRMNMDGSNEQVILQ-DRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYD 4504
T W A+I +M MDGSN IL + I WPNAL++D R+Y+ DAH DYIA + +
Sbjct: 3251 TSWHLQAYIAKMGMDGSNFSRILNWNDGIAWPNALSIDYFTDRIYWADAHLDYIAYADLE 3310
Query: 4503 GSKRRMVLRGS-VRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMG 4327
G R VL GS V H+FAL++F+DY+YWSDW+ I R +K G N VL ++ +RP
Sbjct: 3311 GRHRHTVLSGSKVPHVFALSLFDDYIYWSDWNLKAIVRANKFHGANYTVL-RNTTHRPYD 3369
Query: 4326 FKIVHPSLQSMGSLKTARHPC-SQPARCDNLCIPANTPDLT---------TSSDNFTCMC 4177
I HP Q +PC + C +LC+ A P+ T + F C C
Sbjct: 3370 LHINHPLRQ-----LPYTNPCGTNNGGCSHLCLIAPPPESTYLNIEGYIEEGAPIFKCAC 3424
Query: 4176 AQGF--RSEGRSCVSECKPNDFVC-TKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPP 4006
F + ++CV+ C +C + KCI +W+ C P
Sbjct: 3425 PNQFYLARDMKTCVANCTAGQHLCGGRDEKCIPWFWKCDGEKDCKDGSDE----PATCAP 3480
Query: 4005 FPCIAGQFVCGRT--------------------AQN-------------ATAQCLYASKL 3925
C AG F C T QN ++ +C+ S
Sbjct: 3481 RHCRAGTFQCKNTNCTPSATICDGVDDCGDRSDEQNCDLPCPLSDFKCKSSGRCILDSWR 3540
Query: 3924 CDGVKDCSGGDDEEPAFCENFEC-TEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDE--LN 3754
CDG DC G DE+PA C C + +F C +CIP +CD + DC D SDE
Sbjct: 3541 CDGDADCKDGSDEDPAVCFKRTCDPKTEFSC-KNGRCIPQLWMCDFDNDCGDDSDEPAYM 3599
Query: 3753 CEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDE-PDSCFGIGECTHE-QFQC 3580
C +C + C G + +CIPK +CDG+DDC + DE P++C +C E F+C
Sbjct: 3600 CRQRNCTTGWQRC-PGQSNYRCIPKWLFCDGKDDCRDNSDELPENC---PKCNPETDFKC 3655
Query: 3579 TSGKCIPKRRQCDGTLDCRDGSDE-----KGCKKECA---IVCDN-SCVHADDLCDGKKK 3427
+ +CIPK+ CD DC D SDE KG +EC+ C N C+ + CD +
Sbjct: 3656 GNNRCIPKQWMCDFADDCGDASDENEAVCKGRYRECSESEFRCGNGKCISSRWQCDHEDD 3715
Query: 3426 CNDGSDEDEEACVIKQLLEKENRKCGG------FACDGIVDCEDGSDEKGCPD------- 3286
C D SDE C Q + G F CDG DC D SDE GCP
Sbjct: 3716 CGDNSDEMH--CEGYQCKNGTFQCASGHCIASYFRCDGDRDCRDMSDEVGCPPRFPGGRY 3773
Query: 3285 -----LEC--HLASNKSLICDGTIDCSSGKDEN----NCHNNGESNFFQCSMQ-TIKEWQ 3142
+C +L + S +CDGT DC G DE+ + N FQCS + + +Q
Sbjct: 3774 CPESRFQCNNNLCVSLSDLCDGTDDCGDGSDEDPSVCSDFNCDTLRRFQCSNERCVARYQ 3833
Query: 3141 VCDGRWDCADGLDE-SPEMCASRKARC-FRIGYCDDKKQCLDVSTALCDGIRDCFDGSDE 2968
+CDG +C DG DE + +CAS++ C Y K C++ S +CD DC D SDE
Sbjct: 3834 ICDGVDNCGDGSDENNMTLCASKQKPCDLYTQYQCANKHCIERS-QVCDFSDDCGDASDE 3892
Query: 2967 NPI----------------HCKDMCKGKYRCT--NGRCIDVSARXXXXXXXXXXXXXXXX 2842
HC ++ G Y CT G I +
Sbjct: 3893 LGCHHTSSCSEANRGGCQQHCHNLTDGGYICTCYPGYIIAADNKKKCSDVDECLTRQHTC 3952
Query: 2841 GAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLM 2662
+CH+ N T C C G+ T C + + NG + +
Sbjct: 3953 SHQCHN-----------LNGTYSCSCREGFHLTDGASGVCRAEKEDVILLFVNGQEIRGL 4001
Query: 2661 SLENSQ----VSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSD 2494
+ S+ ++ + + + + I F D + T+ + + + +D R+K
Sbjct: 4002 NWHKSEEFAVIAAEKRIEALDYD-AQQQIVFWADSYDKTIKRSYMV--NAIDGRAKIGFA 4058
Query: 2493 GLIGSWGEEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIV 2314
+ G + TA + D++ +N+Y+TE + + VAK R+++
Sbjct: 4059 QDLNMKGGSKPTA--VAVDWLASNLYWTEMDRTGS----KPRGRVMVAKTDGRYRRSIVN 4112
Query: 2313 NSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFE 2134
S+AV+P I+W+ + P+I + +DG + L+ I
Sbjct: 4113 AGLEVPTSIAVNPQLGRIYWSDAGSAPKIEVSWMDG-----------SKRRPLITEMIRH 4161
Query: 2133 PTSMVLDFSNER-LYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT 1957
P + +D+S + +YW+D IE++ DG R+ + + + PV++D+ ++ +T
Sbjct: 4162 PAGLTIDYSQDHIIYWVDTKLNAIESMRADGSRRKAIVRGDQLRHPVSLDLFESNMFWMT 4221
Query: 1956 RQ-GSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSN 1780
R G + R KF G+ + V V+P ++V H ++ T NPC + C
Sbjct: 4222 RDTGELVRQDKF-GRGVQVVLHRYIVNPS-GLKVYHDKRYN----TSLPNPCDNSTCSHL 4275
Query: 1779 TVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCSP-- 1606
+ VP + P P + C E + A + C N C
Sbjct: 4276 CLLVPGGHR--CACPDASGPPPSHRSTAEVICNAAAEHPRPAPRICP--CQNGGLCKEDA 4331
Query: 1605 --QKTCVCPPGFYGRQCE 1558
+ C C F G CE
Sbjct: 4332 QGELLCECRTQFVGEHCE 4349
Score = 370 bits (951), Expect = e-100
Identities = 260/822 (31%), Positives = 383/822 (45%), Gaps = 23/822 (2%)
Frame = -1
Query: 6522 FNCGNGLCIPEQKVCNRINDCANFADES-NCT---CNENEFRCQSGACIPSKARCNHMQD 6355
F C N CIP+ +C+ +DC + +DE NCT C NEF+C+SG CIP RC+ D
Sbjct: 932 FTCNNQRCIPKSWLCDGDDDCLDNSDEEQNCTKPTCGSNEFQCRSGRCIPQNFRCDQEND 991
Query: 6354 CNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDGTNDCYDGSDEKDCFVE 6175
C D SDE C C T CA +CI WKCD NDC D SDE
Sbjct: 992 CGDNSDEQECGNVTCG-------TSQFACAN-GRCIPNMWKCDSENDCGDSSDE------ 1037
Query: 6174 FDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADGSDEKNCDAKKCTSFEF 5995
G A ++C A QF C T C+P+ W CDG DC D DEK+C C + +F
Sbjct: 1038 -----GDFCAEKTC-AYFQFTCPRTGHCIPQSWVCDGDDDCFDKQDEKDCPPISCLANQF 1091
Query: 5994 SCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNAT-----FRC-TNHRCIPMA 5833
C ++C+ KCDG DC DG D E C S G N FRC + CIP+A
Sbjct: 1092 KCADLRQCVEESYKCDGIPDCNDGSD----EVGCPSMGPNQCNLEKHFRCKSTGFCIPIA 1147
Query: 5832 WRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACELTAVLCDGIQDCSD 5653
W CDG++DC D+ SDE DC T +C + CV A +CDG DC D
Sbjct: 1148 WHCDGSNDCSDH-----SDEQDCGQ-ITCAQNFFKCNNTNCV----FKAYICDGKDDCGD 1197
Query: 5652 GFD---EKNCASLDRQCKPNEWMCD--SGQCIDSGRLCDASVDCVDGSDEWVEICSLSEP 5488
D E C +C +W C S +C++ +CD + DC +GSDE E C L+E
Sbjct: 1198 NSDEGAEHACVPPPFKCPHGQWQCPGVSERCVNITSVCDDTPDCPNGSDEG-EGCDLAEC 1256
Query: 5487 PRRGCPSGWSCLLT-NGTI-GCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSSTRNSCDQT 5314
+ C T NG + C ++ + C+ +CD P G CS
Sbjct: 1257 EHQAGQCSSFCQKTPNGALCVCPPGSEIGEDGYTCID--SNECD-PPGLCSQ-------- 1305
Query: 5313 WNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKANCSHFCIDRRDVGHQCFCAPGYI 5134
C G CSC DGY L P +K TC + V H ++
Sbjct: 1306 -QCTNTKGSYFCSCTDGYVLEP-NKHTC------------------KAVNH----TAAFL 1341
Query: 5133 LSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLTNGVALDYDVKSDLVYW 4954
+ N R+ + A++ R+ + + N VA ++ + ++W
Sbjct: 1342 IISN-----RHSILVADLKEQGLERVPII-------------VENVVATASNMHTGTIFW 1383
Query: 4953 TDVAHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDM 4774
+D+ I+ + +IN+ ++G+A DW+ +N+Y+ D + I V
Sbjct: 1384 SDM----KLKKISRLDRGMEPQEIINT-GLDLVEGLAYDWIAQNLYWLDSKLNTIEVSAE 1438
Query: 4773 RGRFNRILLKGTPLNDPRAIVLDPLQAL--VFWTDWGASAHIGRMNMDGSNEQVILQDRT 4600
G NR++L + PR + +DP +FWTDWG + + R+ MDG+ + I+ +
Sbjct: 1439 NGS-NRLVLVRENITQPRGMCIDPSPGARWIFWTDWGENPRVERIGMDGTMRKTIINTK- 1496
Query: 4599 IRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGS--VRHIFALAVFEDYVY 4426
I WPN L +D +R+YF D+ D+I C Y+G+ R+ VL S + H +L++FED +Y
Sbjct: 1497 IYWPNGLTLDIATKRVYFADSKLDFIDFCYYNGTGRQQVLASSHYLLHPHSLSLFEDTLY 1556
Query: 4425 WSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARC 4246
W+D + + +K G N+ V + +P+ + H SLQ M +PC+ +RC
Sbjct: 1557 WTDRQLNRVLSANKFRGKNQTV-VSHLISQPLSIHVHHASLQPM-----TPNPCA-GSRC 1609
Query: 4245 DNLCIPANTPDLTTSSDNFTCMCAQGFR--SEGRSCVSECKP 4126
+LC+ + ++ + ++C C GF+ SEGR C+ E P
Sbjct: 1610 QHLCLLS-----PSAPEGYSCKCRPGFKLLSEGR-CIEEENP 1645
Score = 350 bits (897), Expect = 3e-94
Identities = 334/1252 (26%), Positives = 508/1252 (39%), Gaps = 78/1252 (6%)
Frame = -1
Query: 5199 CSHFCIDRR------DVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRL---KLF 5047
C+H CI +G +C C+ GY L + K C+ +E LM R K+
Sbjct: 548 CNHMCIVTAVKGAPTGLGFRCACSTGYQLETDLKLCKP----VSEFLMYSQQRFIKGKVL 603
Query: 5046 --TIDGHAKATL--LSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVI 4879
I+G + A + +S V LD+D + + +Y++DV D I + ++
Sbjct: 604 EPVIEGFSDAIMPVVSRRARFVGLDFDARDEFIYYSDVLQDV----IYRVHRNGTGREIV 659
Query: 4878 NSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRG-RFNRILLKGTPLNDPRAIVLDP 4702
+ +G++G+AVDW +N+YY D + V R R LLK L PRAIV+ P
Sbjct: 660 LASQNEGVEGLAVDWASKNLYYIDSRKGTLNVLSTRNVTHRRTLLKN--LKRPRAIVVHP 717
Query: 4701 LQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYI 4522
+ +F+++W A+I R N DGS ++ ++ T+ WPN L++D R+Y+ DA D++
Sbjct: 718 NRGFIFFSEWDRPANITRANTDGSG-LLVFKNVTLGWPNGLSIDFKEDRVYWCDALLDHV 776
Query: 4521 ASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQ 4342
N DG+ + V VRH F++ + D++Y +DW I R+HK+TG ++++++ Q
Sbjct: 777 QHANLDGTDIKTVNSRLVRHPFSIVIHNDWMYITDWRLDAIIRLHKLTGEQEEMMVREPQ 836
Query: 4341 -YRPMGFKIVHPSLQSMGSLKTARHPCSQ-PARCDNLCIPA------NTPDLTTSSDNF- 4189
R G K+ +Q + + PC + C +C T +TTSS +F
Sbjct: 837 TNRLYGVKVYSHEVQRIADTQ----PCHRNNGGCQKICFAVPIGASNGTDGVTTSSPSFG 892
Query: 4188 ----TCMCAQGFRSEGRSCVSECKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVE 4021
C C G R C P+ C +SW
Sbjct: 893 RLQSRCSCPYGERLADDQV--SCIPDPSAEPPVQPCPNSW-------------------- 930
Query: 4020 GVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQF 3841
F C +C+ S LCDG DC DEE C C +F
Sbjct: 931 -----------DFTCN------NQRCIPKSWLCDGDDDCLDNSDEEQN-CTKPTCGSNEF 972
Query: 3840 KCGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCKPDFFACFNGTAISKCIPKEFYCDG 3661
+C +CIP CD+E DC D SDE C +C FAC NG +CIP + CD
Sbjct: 973 QC-RSGRCIPQNFRCDQENDCGDNSDEQECGNVTCGTSQFACANG----RCIPNMWKCDS 1027
Query: 3660 EDDCPEGQDEPDSCFGIGECTHEQFQC-TSGKCIPKRRQCDGTLDCRDGSDEKGC----- 3499
E+DC + DE D C C + QF C +G CIP+ CDG DC D DEK C
Sbjct: 1028 ENDCGDSSDEGDFC-AEKTCAYFQFTCPRTGHCIPQSWVCDGDDDCFDKQDEKDCPPISC 1086
Query: 3498 ---KKECAIVCDNSCVHADDLCDGKKKCNDGSDE------DEEACVIKQLLEKENR-KCG 3349
+ +CA + CV CDG CNDGSDE C LEK R K
Sbjct: 1087 LANQFKCADL--RQCVEESYKCDGIPDCNDGSDEVGCPSMGPNQC----NLEKHFRCKST 1140
Query: 3348 GFA------CDGIVDCEDGSDEKGCPDLECHLASN-----------KSLICDGTIDCSSG 3220
GF CDG DC D SDE+ C + C A N K+ ICDG DC
Sbjct: 1141 GFCIPIAWHCDGSNDCSDHSDEQDCGQITC--AQNFFKCNNTNCVFKAYICDGKDDCGDN 1198
Query: 3219 KDENNCHNNGESNFFQCSMQTIKEWQVCDGRWDCADGLDESPEMCASRKARCFRIGYCDD 3040
DE H C K G+W C G+ E RC I
Sbjct: 1199 SDEGAEH--------ACVPPPFK---CPHGQWQC-PGVSE----------RCVNI----- 1231
Query: 3039 KKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKGKYRCTNGRCIDVSARXXX------- 2881
T++CD DC +GSDE C D+ + +++ G+C +
Sbjct: 1232 --------TSVCDDTPDCPNGSDEGE-GC-DLAECEHQA--GQCSSFCQKTPNGALCVCP 1279
Query: 2880 -XXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKS 2704
EC G+C+Q+C + C C GY N ++ C+ ++ +
Sbjct: 1280 PGSEIGEDGYTCIDSNECDPPGLCSQQCTNT-KGSYFCSCTDGYVLEPN-KHTCKAVNHT 1337
Query: 2703 AEMFITNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSR 2524
A I + L++ Q P+ ++ + ++ T+ ++
Sbjct: 1338 AAFLIISNRHSILVADLKEQGLERVPI------IVENVVATASNMHTGTIFWS------- 1384
Query: 2523 VDIRSKKWSDGLIGSWGEEESTAGL-----ITYDFMHNNVYFTESSEQNRGVLFDRQANI 2359
D++ KK S G +E GL + YD++ N+Y+ D + N
Sbjct: 1385 -DMKLKKISRLDRGMEPQEIINTGLDLVEGLAYDWIAQNLYW-----------LDSKLNT 1432
Query: 2358 YVAKAKDTSTRTLIVNSTGT-INSLAVDPI--KRLIFWTTSAPVPRILSANLDGKPIAQP 2188
A++ S R ++V T + +DP R IFWT PR+ +DG
Sbjct: 1433 IEVSAENGSNRLVLVRENITQPRGMCIDPSPGARWIFWTDWGENPRVERIGMDG------ 1486
Query: 2187 FKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTV-RKFEL 2011
K ++ I+ P + LD + +R+Y+ D I+ ++G R+ V
Sbjct: 1487 -----TMRKTIINTKIYWPNGLTLDIATKRVYFADSKLDFIDFCYYNGTGRQQVLASSHY 1541
Query: 2010 GDTPVTMDVLGGYIYLITRQ-GSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTV 1834
P ++ + +Y RQ + +KF GK V + +S + I V H + +
Sbjct: 1542 LLHPHSLSLFEDTLYWTDRQLNRVLSANKFRGKNQTVVSHL--ISQPLSIHVHHASLQPM 1599
Query: 1833 SHITHQKNPCQSDYCPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQ 1678
+ NPC C + P + C C PG F +S +C++
Sbjct: 1600 T-----PNPCAGSRCQHLCLLSPSAPEG----YSCKCRPG-FKLLSEGRCIE 1641
Score = 345 bits (884), Expect = 1e-92
Identities = 407/1647 (24%), Positives = 633/1647 (37%), Gaps = 135/1647 (8%)
Frame = -1
Query: 5160 QCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKA---TLLSNLTNGVA 4990
+C CA G LS +++ C + + ++ ++ +D H+ T L+NLTN V
Sbjct: 2272 RCECATGK-LSADERKC---EVVNEYLVFATRTEIRAVNLDPHSTEVPFTPLTNLTNVVG 2327
Query: 4989 LDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSLPTKGI--DGIAVDWLGRNIY 4816
LD+D + + +T + A + +N+P + I + KGI +GIA DW + IY
Sbjct: 2328 LDFDFAHNRMLYTQIRPWAKIA--YTKANKPG-HDDITVVLNKGINPEGIAYDWTQQKIY 2384
Query: 4815 YTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWG---ASAHIGRM 4645
+TD ++++I ++ G ++ + + PRAIVLDP +F+TDWG S I R
Sbjct: 2385 WTDSSNNSIYAMNLDGSELVMIAR---VERPRAIVLDPCNGTLFFTDWGRFGTSGKIFRT 2441
Query: 4644 NMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVR 4465
M GS ++ I+ D+ + P+ LA+D +RLY+ DA R+ I + DG R +++ ++
Sbjct: 2442 TMAGSLKRAIV-DKDLSQPSGLAIDYDERRLYWTDAVREKIERSDLDGQNRELLVAATI- 2499
Query: 4464 HIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKI---------VH 4312
+ FA+ VF +Y+YW+D + R K TG N +++ + P +I V+
Sbjct: 2500 YPFAITVFRNYIYWTDLQLRGVYRAEKHTGANMVEMVKRLEDSPRDIRIYSSDRQKCNVN 2559
Query: 4311 PSLQSMGSLKTARHPC---SQPARCDN---------LCIPANTPDLTTSSDNFTCM---- 4180
P + G + HP +CD+ +C P N T + F C
Sbjct: 2560 PCRINNGGCAQSCHPAPNGKAECKCDDSTKVVNEGRMCAPRNN---TCEASKFYCKNGRC 2616
Query: 4179 ------------CAQGFRSEGRSCV-SECKPNDFVCTKTYKCISSWWRXXXXXXXXXXXX 4039
C + C C PN+F C +CI W+
Sbjct: 2617 ISRMWSCDGDDDCGDNSDEDPNYCAYHSCSPNEFRCNNG-RCIFKSWKCDHENDCKDGSD 2675
Query: 4038 XGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDC--SGGDDEEPAFCE- 3868
E C PC+ G+F C A +C+ +++C+GV DC + DE C
Sbjct: 2676 -----ELGCVYPPCVDGEFTC------ANGRCIPQAQVCNGVNDCKDNATSDETHERCPM 2724
Query: 3867 NFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDE--LNCEITSCKPDFFACFNGTAIS 3694
N C KC C+ +CD + DC D SDE L+C +C + F C N
Sbjct: 2725 NTTCPANHLKCEKTNICVEPYWLCDGDNDCGDNSDEDPLHCGQRTCPTNSFRCPN----H 2780
Query: 3693 KCIPKEFYCDGEDDCPEGQDE-PDSCFGIGE-CTHEQFQCTSGKCIPKRRQCDGTLDCRD 3520
+CIP +YCDG+DDC +G DE PD C G C + F C +G CIP+ CDG DC D
Sbjct: 2781 RCIPATWYCDGDDDCGDGADEPPDYCKSEGRTCFGDLFTCDNGNCIPRIYICDGDNDCLD 2840
Query: 3519 GSDE--------KGCKKECAIVCDNS-------CVHADDLCDGKKKCNDGSDEDE--EAC 3391
SDE + C +E C + C+ +CDG C DG+DE+ C
Sbjct: 2841 NSDEDNRHQCNDRKCDEETEFTCVENKSWQRAQCIPKKWICDGDPDCVDGADENTTLHNC 2900
Query: 3390 VIKQLLEKENRKCGGFACDGIVDCEDGSDEKGCPDLECHLASNKSLICDGTIDCSSGKDE 3211
+Q ++ CG C NK ICD DC G DE
Sbjct: 2901 ATQQPCGEDMFTCGNGRC-----------------------INKGWICDHDNDCGDGTDE 2937
Query: 3210 ----NNCHNNGESNFFQC-SMQTIKEWQVCDGRWDCADGLDESPEMCASRKARCFRIGYC 3046
N+ + + F C + + I+ CDG DC D DE CA C + +
Sbjct: 2938 GKFCNSKYKTCSAQEFTCQNFKCIRNQSRCDGEDDCGDHSDEVG--CAKENITCPQGQFA 2995
Query: 3045 DDKKQCLDVSTALCDGIRDCFDGSDENPIHCK-DMC-KGKYRCTNGRCIDVSARX----X 2884
QC+D + +C+ DC D SDE P HC D C K + +C+D
Sbjct: 2996 CTNGQCIDYN-LVCNKYPDCADESDE-PAHCNVDECAKVEINQCGHKCVDTLTGYYCDCN 3053
Query: 2883 XXXXXXXXXXXXXXGAEC-HHFGVCAQKCWMAFNHTA---RCHCAPGYARTKNDENECEP 2716
EC G C+Q C ++T C C Y +NDE+ C+
Sbjct: 3054 EGYKLLADGKACADVDECLEQPGACSQHC----SNTPGGFYCKCDETYYERQNDEHTCKR 3109
Query: 2715 LSKSAEMFI-TNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVG 2539
K I TN + MS++ Q +++ MN++ +DF R MY
Sbjct: 3110 KDKIPPWLIFTNKYYVRNMSVDGHQYNLMHQDL---MNVV--ALDFD---IREEYMYFCD 3161
Query: 2538 IGNSRVDIRSKKWSDGLIGSWGE---EESTAGL--ITYDFMHNNVYFTESSEQNRGVLFD 2374
+ + +D + E + GL I D++ +Y+ + +N V
Sbjct: 3162 VTAKTIFRAKYGEADDEMPPEREAVIRHDSHGLEGIAIDWVGRKLYWLDRHSKNLDV--- 3218
Query: 2373 RQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIA 2194
D S R + + ++ V P +++T+ I +DG +
Sbjct: 3219 --------SELDGSKRKTLRSGVVDPRAIVVHPGIGYLYFTSWHLQAYIAKMGMDGSNFS 3270
Query: 2193 QPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFE 2014
+ I P ++ +D+ +R+YW D I +GR R TV
Sbjct: 3271 RILNWND---------GIAWPNALSIDYFTDRIYWADAHLDYIAYADLEGRHRHTVLSGS 3321
Query: 2013 LGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHT 1837
+ + YIY +I R +KF G Y + + HP +
Sbjct: 3322 KVPHVFALSLFDDYIYWSDWNLKAIVRANKFHGA--NYTVLRNTTHRPYDLHINHPLRQ- 3378
Query: 1836 VSHITHQKNPCQSDYCPSNTVCV---PDQD---------KNGILIPKCLCGPGRFFEVST 1693
NPC ++ + +C+ P + + G I KC C +
Sbjct: 3379 ----LPYTNPCGTNNGGCSHLCLIAPPPESTYLNIEGYIEEGAPIFKCACPNQFYLARDM 3434
Query: 1692 KKCMQLREKDQEASQCGDYFCYNNAGCSPQKTCVCPPGFYGRQCEINECSETCWNGETCA 1513
K C+ G + C G +K C P F+ E +C + TCA
Sbjct: 3435 KTCV-------ANCTAGQHLC----GGRDEK---CIPWFWKCDGE-KDCKDGSDEPATCA 3479
Query: 1512 VQEFGSTTNVVCHCPSNYTQSSCATNVCEGV--CGPRGSCKT--VPCPKDEPHCRSYSFC 1345
+ + T C + T + + +C+GV CG R + +PCP + C+S C
Sbjct: 3480 PRHCRAGT---FQCKN--TNCTPSATICDGVDDCGDRSDEQNCDLPCPLSDFKCKSSGRC 3534
Query: 1344 ECDKGWTGPHCRHKADAK--------VCYGH---------CFSGGACDGEGPLNLRCSCG 1216
D W C AD K VC+ C +G + CG
Sbjct: 3535 ILD-SW---RCDGDADCKDGSDEDPAVCFKRTCDPKTEFSCKNGRCIPQLWMCDFDNDCG 3590
Query: 1215 DGLTGNRCQNCVGHECLNG-GFCSYANSNRSLPHCICPSGFTGDHCEEYL--CKDACPFG 1045
D + C C G C ++ R +P + G D C + + CP
Sbjct: 3591 DD-SDEPAYMCRQRNCTTGWQRCPGQSNYRCIPKWLFCDG--KDDCRDNSDELPENCP-- 3645
Query: 1044 SKCTYDITKPMDPITCSCEQNAAAHNTDCSPICQKQPNWCHNGGR-CLDTPGYPGKCKCL 868
KC + C +Q DC + C R C ++ G KC+
Sbjct: 3646 -KCNPETDFKCGNNRCIPKQWMCDFADDCGDASDENEAVCKGRYRECSESEFRCGNGKCI 3704
Query: 867 PRFAGPRCDVPVQCDDYCTNNSKC---TITNGTHFEC---DCKPGFKGLRCEQETKCSEC 706
+ +CD C D ++ C NGT F+C C + RC+ + C +
Sbjct: 3705 S--SRWQCDHEDDCGDN-SDEMHCEGYQCKNGT-FQCASGHCIASY--FRCDGDRDCRDM 3758
Query: 705 SNEAKCIKKPSGTVICQCPQGLGGEYC 625
S+E C P+ GG YC
Sbjct: 3759 SDEVGC-----------PPRFPGGRYC 3774
Score = 206 bits (523), Expect = 8e-51
Identities = 168/589 (28%), Positives = 267/589 (44%), Gaps = 15/589 (2%)
Frame = -1
Query: 5847 CIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACELTAVLCDGI 5668
C+P RCDG DC +G V C + RCA+ + C A+ C+
Sbjct: 43 CVPKEKRCDGYLDCRTGRDEVGCSGVACRLDQF------RCANG---LKCIDAALKCNHR 93
Query: 5667 QDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASVDCVDGSDEWVEICSLSEP 5488
DC D DE+ C C ++ C + CI CD DC D SDE +++ P
Sbjct: 94 DDCGDNSDEQGCNF--PPCHHAQFRCTNALCIPYNFHCDGYHDCADKSDE-ANCTAIACP 150
Query: 5487 PRRG-CPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSSTRNSCDQTW 5311
+ CP G + +GT C+ + QLCDG+RDC G DE+ + +C + SC+ +
Sbjct: 151 DNKHLCPRGGA----SGTPKCILKSQLCDGKRDCEDGSDEETNCSIASCPAL--SCE--F 202
Query: 5310 NCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPK-ANCSHFCIDRRDVGHQCFCAPGYI 5134
C C C G L+P D +TC+ C + +C C + + C CA GY
Sbjct: 203 KCGPSLTGGVCYCKPGQSLAP-DNRTCVDLDECAEWGHCDQLCTNTLG-SYTCQCAQGYT 260
Query: 5133 LSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLTNGVALDYDVKSDLVYW 4954
L + K C D +++ + + G ++ +L+N T + + + +YW
Sbjct: 261 LINDSK-CIAPDANNLQLIFAHDRAIMRMLPHG-SEPKILANATAAAGVTFHYARNTLYW 318
Query: 4953 TDV---------AHDGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRN 4801
+D+ NKA P T+ + +AVDW+G IY D
Sbjct: 319 SDIKTRKVQSLPLDAQNKAVSPFDQTLPGTWAPV---------ALAVDWVGDKIYVADLV 369
Query: 4800 HDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQ 4621
I V ++ G+++ ++L G+ L P + LDP L+F D G + R +MDG++ +
Sbjct: 370 GQKIDVFELSGQWHAVVL-GSNLTSPADLALDPTAGLMFVADGG---QVLRAHMDGTHAR 425
Query: 4620 VILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRG-SVRHIFALAV 4444
I+ + + + + VD ++R+++ D+ DYI S +Y+G+ R MVLRG V LA+
Sbjct: 426 SIVSEAAYK-ASGVTVDIISKRVFWCDSLLDYIESVDYEGAHRVMVLRGQQVPSPSRLAL 484
Query: 4443 FEDYVYWSDWHNHTIERVHKITG-TNRKVLIQDKQYR-PMGFKIVHPSLQSMGSLKTARH 4270
FE+ +YW+D I V K G T+ +V + K R P G VH Q S +
Sbjct: 485 FENRIYWTDATKQGIMSVDKFEGPTSIQVTYKAKDIREPKGIIAVHALSQPRVS-----N 539
Query: 4269 PC-SQPARCDNLCIPANTPDLTTSSDNFTCMCAQGFRSEGRSCVSECKP 4126
PC + C+++CI T F C C+ G++ E + + CKP
Sbjct: 540 PCGNNNGGCNHMCIVTAVKGAPTGL-GFRCACSTGYQLE--TDLKLCKP 585
Score = 149 bits (375), Expect = 1e-33
Identities = 115/374 (30%), Positives = 154/374 (40%), Gaps = 24/374 (6%)
Frame = -1
Query: 6159 GSVSAPRS--CDAKTQFACLATRTCMPKHWQCDGQPDCADGSDE--KNCDAKKCTSFEFS 5992
G + APR+ C+A ++F C R C+ + W CDG DC D SDE C C+ EF
Sbjct: 2594 GRMCAPRNNTCEA-SKFYCKNGR-CISRMWSCDGDDDCGDNSDEDPNYCAYHSCSPNEFR 2651
Query: 5991 CESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNATFRCTNHRCIPMAWRCDGTD 5812
C + +CI KCD DC DG DE C G F C N RCIP A C+G +
Sbjct: 2652 CNNG-RCIFKSWKCDHENDCKDGSDELGCVYPPCVDG---EFTCANGRCIPQAQVCNGVN 2707
Query: 5811 DCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVA----CELTAV------LCDGIQD 5662
DC DNA TS RC T A CE T + LCDG D
Sbjct: 2708 DCKDNA--------------TSDETHERCPMNTTCPANHLKCEKTNICVEPYWLCDGDND 2753
Query: 5661 CSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASVDCVDGSDEWVEICSLSEPPR 5482
C D DE R C N + C + +CI + CD DC DG+DE + C +
Sbjct: 2754 CGDNSDEDPLHCGQRTCPTNSFRCPNHRCIPATWYCDGDDDCGDGADEPPDYC---KSEG 2810
Query: 5481 RGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSSTRNSCDQTWNCQ 5302
R C + L T C+ +CDG DC+ DE DN + C+ + + + C
Sbjct: 2811 RTC---FGDLFTCDNGNCIPRIYICDGDNDCLDNSDE--DN-RHQCNDRKCDEETEFTCV 2864
Query: 5301 RHAGFESCSCDDGYHLSPYDKKTCLRSPSC----PKANCSHFCIDRRDVGHQCF-CAPGY 5137
+ ++ C K C P C + H C ++ G F C G
Sbjct: 2865 ENKSWQRAQCIP-------KKWICDGDPDCVDGADENTTLHNCATQQPCGEDMFTCGNGR 2917
Query: 5136 ILS-----ENQKDC 5110
++ ++ DC
Sbjct: 2918 CINKGWICDHDNDC 2931
Score = 125 bits (314), Expect = 1e-26
Identities = 160/662 (24%), Positives = 245/662 (36%), Gaps = 26/662 (3%)
Frame = -1
Query: 3576 SGKCIPKRRQCDGTLDCRDGSDEKGCKKECAIVCDNSCVHADDLCDGKKKCND----GSD 3409
+G C+PK ++CDG LDCR G DE GC + C + D KCN G +
Sbjct: 40 TGPCVPKEKRCDGYLDCRTGRDEVGCSGVACRLDQFRCANGLKCIDAALKCNHRDDCGDN 99
Query: 3408 EDEEACVIKQLLEKE----NRKC--GGFACDGIVDCEDGSDEKGCPDLECHLASNKSLIC 3247
DE+ C + N C F CDG DC D SDE C + C NK L
Sbjct: 100 SDEQGCNFPPCHHAQFRCTNALCIPYNFHCDGYHDCADKSDEANCTAIAC--PDNKHL-- 155
Query: 3246 DGTIDCSSGKDENNCHNNGESNFFQCSMQTIKEWQVCDGRWDCADGLDESPEMCASRKAR 3067
C G S +C +++ Q+CDG+ DC DG DE +
Sbjct: 156 --------------CPRGGASGTPKCILKS----QLCDGKRDCEDGSDE--------ETN 189
Query: 3066 CFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDENPIHCKDMCKGKYRCTNGRCIDVSARX 2887
C I C +L G+ C G P N C+D+
Sbjct: 190 C-SIASCPALSCEFKCGPSLTGGVCYCKPGQSLAP-------------DNRTCVDLD--- 232
Query: 2886 XXXXXXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSK 2707
EC +G C Q C + C CA GY ND P +
Sbjct: 233 -----------------ECAEWGHCDQLCTNTLG-SYTCQCAQGYTLI-NDSKCIAPDAN 273
Query: 2706 SAEMFITNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMY----TVG 2539
+ ++ + + M S+ +L G+ F Y R TL + T
Sbjct: 274 NLQLIFAHDRAIMRMLPHGSEPKILANA------TAAAGVTFHY--ARNTLYWSDIKTRK 325
Query: 2538 IGNSRVDIRSK---KWSDGLIGSWGEEESTAGLITYDFMHNNVYFTESSEQNRGVL-FDR 2371
+ + +D ++K + L G+W + D++ + +Y + Q V
Sbjct: 326 VQSLPLDAQNKAVSPFDQTLPGTWAPV-----ALAVDWVGDKIYVADLVGQKIDVFELSG 380
Query: 2370 QANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQ 2191
Q + V + TS LA+DP L+F A ++L A++DG
Sbjct: 381 QWHAVVLGSNLTSPA-----------DLALDPTAGLMF---VADGGQVLRAHMDGTHA-- 424
Query: 2190 PFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFEL 2011
+++V ++ + + +D ++R++W D L IE+V ++G R V + +
Sbjct: 425 ---------RSIVSEAAYKASGVTVDIISKRVFWCDSLLDYIESVDYEGAHRVMVLRGQQ 475
Query: 2010 GDTPVTMDVLGGYIYL--ITRQGSIHRMHKFTGKTNKYV----QKIREVSPRIQIRVAHP 1849
+P + + IY T+QG I + KF G T+ V + IRE I
Sbjct: 476 VPSPSRLALFENRIYWTDATKQG-IMSVDKFEGPTSIQVTYKAKDIREPKGII------- 527
Query: 1848 AKHTVSHITHQKNPCQSDYCPSNTVCVPDQDKNGI--LIPKCLCGPGRFFEVSTKKCMQL 1675
A H +S NPC ++ N +C+ K L +C C G E K C +
Sbjct: 528 AVHALSQ-PRVSNPCGNNNGGCNHMCIVTAVKGAPTGLGFRCACSTGYQLETDLKLCKPV 586
Query: 1674 RE 1669
E
Sbjct: 587 SE 588
Score = 118 bits (295), Expect = 2e-24
Identities = 79/247 (31%), Positives = 112/247 (44%), Gaps = 15/247 (6%)
Frame = -1
Query: 6555 YCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCT---CNENEFRCQSGA-CI 6388
+C+T P G C+P++K C+ DC DE C+ C ++FRC +G CI
Sbjct: 25 FCNTPTGAPAEGARLTGPCVPKEKRCDGYLDCRTGRDEVGCSGVACRLDQFRCANGLKCI 84
Query: 6387 PSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDGTNDCY 6208
+ +CNH DC D SDE GC F C C T + CI ++ CDG +DC
Sbjct: 85 DAALKCNHRDDCGDNSDEQGCNFPPCHHAQ-------FRC-TNALCIPYNFHCDGYHDCA 136
Query: 6207 DGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADGSDEK- 6031
D SDE +C +++ P + + T C+ K CDG+ DC DGSDE+
Sbjct: 137 DKSDEANC--------TAIACPDNKHLCPRGGASGTPKCILKSQLCDGKRDCEDGSDEET 188
Query: 6030 NCDAKKC--TSFEFSCESSKK-----CIPLEQKCDGRRDCPDGEDEHQ---CETECDSKG 5881
NC C S EF C S C P + R C D ++ + C+ C +
Sbjct: 189 NCSIASCPALSCEFKCGPSLTGGVCYCKPGQSLAPDNRTCVDLDECAEWGHCDQLCTNTL 248
Query: 5880 GNATFRC 5860
G+ T +C
Sbjct: 249 GSYTCQC 255
Score = 113 bits (283), Expect = 5e-23
Identities = 92/380 (24%), Positives = 167/380 (43%), Gaps = 14/380 (3%)
Frame = -1
Query: 5241 KKTCLRSPSCPKAN--CSHFCIDRRDVGHQCFCAPGYILSENQKDC--RRNDTIEAEILM 5074
KK L C N C H CI C C GY EN+ +C + + +++ M
Sbjct: 1920 KKRALMQHPCQTNNGGCKHLCIPGPGATRTCACGIGY-RKENEINCVAYKIFAVVSQLDM 1978
Query: 5073 VYGHRLKLFTIDGHAKATLLSNLTNGVA-LDYDVKSDLVYWTDVAHDGNKAGITSMSNQP 4897
+ G+ L D +S + + +D + +YW + S N
Sbjct: 1979 IRGYSLS----DSSEAMVPISGPGHHILHVDVMYREQWIYWAEYNRGYWNGIFRSRPNGT 2034
Query: 4896 NTYRVI-NSLPTKGIDGIAVDWLGRNIYYTD--RNHDAIAVCDMRGRFNRILLKGTPLND 4726
+ V+ + + + GI G+ +DW+ N+Y+T+ + + + VC + G ++L+K T +
Sbjct: 2035 DLQHVVKDGIGSNGIRGLTIDWVAGNMYFTNVYPHENYVEVCWLDGSNRKVLVK-TTTDA 2093
Query: 4725 PRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYF 4546
PR + ++P++ L++W D+G IG+ +DGS + L I P L +D +Y+
Sbjct: 2094 PRELAVNPIKRLLYWIDYGQHPRIGKALLDGS-KWTPLVTSGISLPRDLTIDMQTHDIYW 2152
Query: 4545 GDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNR 4366
D+ D I +Y+G+ R+ ++R + + +AV+ + VYW D + T+ + K +
Sbjct: 2153 VDSKLDTIQKISYNGANRK-IIRRDLPNPMGIAVYLNDVYWVDRNLMTVFKASKHSANET 2211
Query: 4365 KVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPAR--CDNLCI---PANTPDLTTS 4201
++ + I + + Q +PC+ CD LC P T+
Sbjct: 2212 ATSVRTNLEKLRDIAIYNINNQPQDD----TNPCAHLGNGGCDQLCFSFPPDGGASGTSG 2267
Query: 4200 SDNFTCMCAQG-FRSEGRSC 4144
NF C CA G ++ R C
Sbjct: 2268 GRNFRCECATGKLSADERKC 2287
Score = 112 bits (279), Expect = 2e-22
Identities = 76/209 (36%), Positives = 90/209 (42%), Gaps = 13/209 (6%)
Frame = -1
Query: 3975 GRTAQNA--TAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTS 3802
G A+ A T C+ K CDG DC G DE C C QF+C + KCI
Sbjct: 31 GAPAEGARLTGPCVPKEKRCDGYLDCRTGRDE--VGCSGVACRLDQFRCANGLKCIDAAL 88
Query: 3801 VCDKEKDCDDGSDELNCEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDS 3622
C+ DC D SDE C C F C N + CIP F+CDG DC + DE +
Sbjct: 89 KCNHRDDCGDNSDEQGCNFPPCHHAQFRCTN----ALCIPYNFHCDGYHDCADKSDEA-N 143
Query: 3621 CFGIGECTHEQFQCTSG------KCIPKRRQCDGTLDCRDGSDEK-GCK-KEC-AIVCDN 3469
C I C + C G KCI K + CDG DC DGSDE+ C C A+ C+
Sbjct: 144 CTAIA-CPDNKHLCPRGGASGTPKCILKSQLCDGKRDCEDGSDEETNCSIASCPALSCEF 202
Query: 3468 SCVHADDLCDGKKKCNDGSD--EDEEACV 3388
C L G C G D CV
Sbjct: 203 KC--GPSLTGGVCYCKPGQSLAPDNRTCV 229
Score = 110 bits (276), Expect = 4e-22
Identities = 71/265 (26%), Positives = 104/265 (38%), Gaps = 27/265 (10%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCT--------CNEN 6418
D+ D +C C+ G F C +G CI C+ DC + +DE C C E+
Sbjct: 3718 DNSDEMHCEGYQCKNGTFQCASGHCIASYFRCDGDRDCRDMSDEVGCPPRFPGGRYCPES 3777
Query: 6417 EFRCQSGACIPSKARCNHMQDCNDASDE--IGCPFRNCSALNEFGMTGLINCATTSQCIH 6244
F+C + C+ C+ DC D SDE C NC L F + +C+
Sbjct: 3778 RFQCNNNLCVSLSDLCDGTDDCGDGSDEDPSVCSDFNCDTLRRFQ-------CSNERCVA 3830
Query: 6243 PSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDG 6064
CDG ++C DGSDE + + S + CD TQ+ C A + C+ + CD
Sbjct: 3831 RYQICDGVDNCGDGSDENNMTL-------CASKQKPCDLYTQYQC-ANKHCIERSQVCDF 3882
Query: 6063 QPDCADGSDEKNCDAKKCTSFEFSCESSKKCIPLEQ-------------KCDGRRDCPDG 5923
DC D SDE C S + C L D ++ C D
Sbjct: 3883 SDDCGDASDELGCHHTSSCSEANRGGCQQHCHNLTDGGYICTCYPGYIIAADNKKKCSDV 3942
Query: 5922 ED----EHQCETECDSKGGNATFRC 5860
++ +H C +C + G + C
Sbjct: 3943 DECLTRQHTCSHQCHNLNGTYSCSC 3967
Score = 109 bits (273), Expect = 8e-22
Identities = 106/391 (27%), Positives = 177/391 (45%), Gaps = 32/391 (8%)
Frame = -1
Query: 5214 CPKANCSHFCI--DRRDVGHQCFCAPGY-ILSENQKDCRRNDTIEAE---ILMVYGHRLK 5053
C + C H C+ G+ C C PG+ +LSE + IE E +++V G ++
Sbjct: 1604 CAGSRCQHLCLLSPSAPEGYSCKCRPGFKLLSEGR-------CIEEENPFLMVVKGTQIV 1656
Query: 5052 LFTIDG-HAKATLLS---NLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYR 4885
++G A+A L+ + + LD+D K + +YW D ++ + +
Sbjct: 1657 DLPLNGGDARAGALAPVIGIESSTGLDFDRKGETLYWVQGREDDDENCTIYTTPYGGGNK 1716
Query: 4884 VINSLPTKGIDG----IAVDWLGRNIYYTDR---NHDAIAVCDMRGRFNRILL--KGTP- 4735
+ GI G IA DWLGRN+Y +R N +A+ V D + ++ I+L G P
Sbjct: 1717 TLFLGIENGIVGAPYTIAFDWLGRNLYIGNRVASNIEAVRV-DGKQKYRTIILANDGYPN 1775
Query: 4734 -LNDPRAIVLDPLQALVFWTDWG---ASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDA 4567
++ P+ I LDP + +FW D G IGR++M+G N V+ Q+ P +LAVD
Sbjct: 1776 SVSRPKQIALDPTEGKLFWIDEGVLEVPIKIGRVDMNGQNPIVVFQE--FAHPESLAVDT 1833
Query: 4566 PAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIF---ALAVFEDYVYWSDWHNHTIE 4396
+ +Y+ ++ I +Y+G ++L + +L + + +Y+ D I
Sbjct: 1834 EKKMVYYSASNPAVIGVMDYNGDDHTLILMKDSHPMAKPRSLGILDHRLYYLDPLYERIV 1893
Query: 4395 RVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLK---TARHPC-SQPARCDNLCIP 4228
R+ G N K ++ ++ L+SM K +HPC + C +LCIP
Sbjct: 1894 RIDLPHGDNPKTIVDNES-----------DLRSMMIYKKRALMQHPCQTNNGGCKHLCIP 1942
Query: 4227 ANTPDLTTSSDNFTCMCAQGFRSEGR-SCVS 4138
P T TC C G+R E +CV+
Sbjct: 1943 G--PGATR-----TCACGIGYRKENEINCVA 1966
Score = 99.0 bits (245), Expect = 1e-18
Identities = 91/324 (28%), Positives = 124/324 (38%), Gaps = 28/324 (8%)
Frame = -1
Query: 6042 SDEKNCDAKKCTSFEFSCESSKKCIP---LEQKCDGRRDCPDGEDEHQCETECDSKGGNA 5872
SD + C+ C C S P E KCD D +E + ++ +
Sbjct: 2551 SDRQKCNVNPCRINNGGCAQSCHPAPNGKAECKCD---DSTKVVNEGRMCAPRNNTCEAS 2607
Query: 5871 TFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACEL 5692
F C N RCI W CDG DDC DN+ ++ + A + RC + C+
Sbjct: 2608 KFYCKNGRCISRMWSCDGDDDCGDNS----DEDPNYCAYHSCSPNEFRCNNGRCI----F 2659
Query: 5691 TAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASVDCVDG--SDE 5518
+ CD DC DG DE C + C E+ C +G+CI ++C+ DC D SDE
Sbjct: 2660 KSWKCDHENDCKDGSDELGC--VYPPCVDGEFTCANGRCIPQAQVCNGVNDCKDNATSDE 2717
Query: 5517 WVEICSLSEPPRRGCPSG-WSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQ--------C 5365
E C P CP+ C TN C++ LCDG DC DE C
Sbjct: 2718 THERC----PMNTTCPANHLKCEKTN---ICVEPYWLCDGDNDCGDNSDEDPLHCGQRTC 2770
Query: 5364 DNPQGNCSSTRNSCDQTWNCQRHAGFESC--SCDDGYHLSPYDKKTCLRSP-SCPKANC- 5197
C + R TW C G + C D+ + +TC +C NC
Sbjct: 2771 PTNSFRCPNHR-CIPATWYCD---GDDDCGDGADEPPDYCKSEGRTCFGDLFTCDNGNCI 2826
Query: 5196 --------SHFCIDRRDVG--HQC 5155
+ C+D D HQC
Sbjct: 2827 PRIYICDGDNDCLDNSDEDNRHQC 2850
Score = 90.9 bits (224), Expect = 4e-16
Identities = 197/881 (22%), Positives = 306/881 (34%), Gaps = 88/881 (9%)
Frame = -1
Query: 2775 RCHCAPGYARTKNDENECEPLSK----SAEMFITNGNRLHLMSLENSQVSVLRPVFNIKM 2608
RC C+ GY + + D C+P+S+ S + FI G L + +E +++ PV + +
Sbjct: 567 RCACSTGY-QLETDLKLCKPVSEFLMYSQQRFI-KGKVLEPV-IEGFSDAIM-PVVSRRA 622
Query: 2607 NLIPGGIDFG-------YDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEEESTAGL 2449
+ G+DF Y ++Y V + +I ++G+ G
Sbjct: 623 RFV--GLDFDARDEFIYYSDVLQDVIYRVHRNGTGREIVLASQNEGVEG----------- 669
Query: 2448 ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIK 2269
+ D+ N+Y+ +S + VL R T RTL+ N ++ V P +
Sbjct: 670 LAVDWASKNLYYIDSRKGTLNVLSTRNV---------THRRTLLKNLKRP-RAIVVHPNR 719
Query: 2268 RLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFE--PTSMVLDFSNERL 2095
IF++ I AN DG + LV +N+ P + +DF +R+
Sbjct: 720 GFIFFSEWDRPANITRANTDGSGL-------------LVFKNVTLGWPNGLSIDFKEDRV 766
Query: 2094 YWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT-RQGSIHRMHKFTG 1918
YW D L ++ + DG D +TV L P ++ + ++Y+ R +I R+HK TG
Sbjct: 767 YWCDALLDHVQHANLDGTDIKTVNS-RLVRHPFSIVIHNDWMYITDWRLDAIIRLHKLTG 825
Query: 1917 KTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSNTVC--VPDQDKNGI 1744
+ + + + + + ++V H V I PC + +C VP NG
Sbjct: 826 EQEEMMVREPQTNRLYGVKV---YSHEVQRIA-DTQPCHRNNGGCQKICFAVPIGASNGT 881
Query: 1743 ------------LIPKCLCGPGRFFEVSTKKCMQLREKDQEASQC---GDYFCYNNAGCS 1609
L +C C G C+ + C D+ C NN C
Sbjct: 882 DGVTTSSPSFGRLQSRCSCPYGERLADDQVSCIPDPSAEPPVQPCPNSWDFTC-NNQRCI 940
Query: 1608 PQKTCVCPPGFYGRQCEINECSETCWNGETCAVQEFGSTTNVVCHC-PSNY---TQSSCA 1441
P K+ +C C N E TC EF + C P N+ ++ C
Sbjct: 941 P-KSWLCDG---DDDCLDNSDEEQNCTKPTCGSNEFQCRSG---RCIPQNFRCDQENDCG 993
Query: 1440 TNVCEGVCG------PRGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHKADAKVCY- 1282
N E CG + +C C + C S + C D G C K A +
Sbjct: 994 DNSDEQECGNVTCGTSQFACANGRCIPNMWKCDSENDCG-DSSDEGDFCAEKTCAYFQFT 1052
Query: 1281 ----GHCF-SGGACDGEGPLNLRCSCGDGLTGNRCQNCVGHECLNGGF-CSYANSNRSLP 1120
GHC CDG+ D ++C CL F C+ L
Sbjct: 1053 CPRTGHCIPQSWVCDGD---------DDCFDKQDEKDCPPISCLANQFKCA------DLR 1097
Query: 1119 HCICPSGFTGDHCEEYLCKDACPFGSKCTYDITKP-MDPITCSCEQNAAAHNTD-CSPIC 946
C+ E Y C D P + + ++ P M P C+ E++ +T C PI
Sbjct: 1098 QCV---------EESYKC-DGIPDCNDGSDEVGCPSMGPNQCNLEKHFRCKSTGFCIPIA 1147
Query: 945 QKQPNW-CHNGGRCLDTPGYP--GKCKCLPRFAGPRCDVPVQCDDYCTNNSKCTITNGTH 775
W C C D G+ C F + NN+ C
Sbjct: 1148 -----WHCDGSNDCSDHSDEQDCGQITCAQNF-------------FKCNNTNCV------ 1183
Query: 774 FECDCKPGFKGLRCEQETKCSECSNEA---KCIKKPSGTVICQCPQGLG-----GEYCEK 619
FK C+ + C + S+E C+ P +CP G E C
Sbjct: 1184 --------FKAYICDGKDDCGDNSDEGAEHACVPPP-----FKCPHGQWQCPGVSERCVN 1230
Query: 618 ITATSCHQLECKNG--------------------GYCLKPDPSANRTSPTCLCSPGFK-- 505
IT+ +C NG +C K A C+C PG +
Sbjct: 1231 ITSVCDDTPDCPNGSDEGEGCDLAECEHQAGQCSSFCQKTPNGA-----LCVCPPGSEIG 1285
Query: 504 --GLLC-SSNACE--NFCLHDGNCTLDEYFEPQCECYQAFI 397
G C SN C+ C T YF C C ++
Sbjct: 1286 EDGYTCIDSNECDPPGLCSQQCTNTKGSYF---CSCTDGYV 1323
Score = 90.5 bits (223), Expect = 5e-16
Identities = 201/917 (21%), Positives = 315/917 (33%), Gaps = 132/917 (14%)
Frame = -1
Query: 2775 RCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQVSV-LRPVFNIKMNLI 2599
RC CA G + DE +CE +++ +F T + ++L+ V P+ N+ N++
Sbjct: 2272 RCECATG--KLSADERKCEVVNEYL-VFATR-TEIRAVNLDPHSTEVPFTPLTNLT-NVV 2326
Query: 2598 PGGIDFGYDVFRTTLMYTVGIGNSRVDIR--SKKWSDGLIGSWGEEESTAGLITYDFMHN 2425
G+DF D ++YT +++ +K D + + + G I YD+
Sbjct: 2327 --GLDF--DFAHNRMLYTQIRPWAKIAYTKANKPGHDDITVVLNKGINPEG-IAYDWTQQ 2381
Query: 2424 NVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTS 2245
+Y+T+SS N A D S +I ++ +DP +F+T
Sbjct: 2382 KIYWTDSSN-----------NSIYAMNLDGSELVMIARVERP-RAIVLDPCNGTLFFTDW 2429
Query: 2244 APVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTI 2065
GK I + GS +A+V++++ +P+ + +D+ RLYW D ++ I
Sbjct: 2430 GRF------GTSGK-IFRTTMAGSLK-RAIVDKDLSQPSGLAIDYDERRLYWTDAVREKI 2481
Query: 2064 ETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITRQ-GSIHRMHKFTGKTNKYVQKIR 1888
E DG++R + + P + V YIY Q ++R K TG + K
Sbjct: 2482 ERSDLDGQNRELLVAATI--YPFAITVFRNYIYWTDLQLRGVYRAEKHTGANMVEMVKRL 2539
Query: 1887 EVSPR-IQIRVAHPAKHTVSHITHQKNPCQSDYCPS---NTVCVPDQDKNGILIPKCLCG 1720
E SPR I+I + K V+ C P+ C D D ++ +C
Sbjct: 2540 EDSPRDIRIYSSDRQKCNVNPCRINNGGCAQSCHPAPNGKAECKCD-DSTKVVNEGRMCA 2598
Query: 1719 P-GRFFEVSTKKCMQLR----------------EKDQEASQCGDYFC------YNNAGC- 1612
P E S C R D++ + C + C NN C
Sbjct: 2599 PRNNTCEASKFYCKNGRCISRMWSCDGDDDCGDNSDEDPNYCAYHSCSPNEFRCNNGRCI 2658
Query: 1611 ---------------SPQKTCVCPPGFYGR-QCEINEC---SETCWNGETCAVQEFGSTT 1489
S + CV PP G C C ++ C C T
Sbjct: 2659 FKSWKCDHENDCKDGSDELGCVYPPCVDGEFTCANGRCIPQAQVCNGVNDCKDNATSDET 2718
Query: 1488 NVVC----HCPSNYTQSSCATNVC---------EGVCGPRGS-----CKTVPCPKDEPHC 1363
+ C CP+N+ + TN+C + CG C CP + C
Sbjct: 2719 HERCPMNTTCPANHLKCE-KTNICVEPYWLCDGDNDCGDNSDEDPLHCGQRTCPTNSFRC 2777
Query: 1362 RSYS------FC----ECDKGWTGPHCRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGD 1213
++ +C +C G P K++ + C+G F +C +
Sbjct: 2778 PNHRCIPATWYCDGDDDCGDGADEPPDYCKSEGRTCFGDLF---------------TCDN 2822
Query: 1212 GLTGNRCQNCVG-HECLNGGFCSYANSNRSLPH------CICPSGFTGDHCEEYLCKDAC 1054
G R C G ++CL+ NS+ H C + FT + +
Sbjct: 2823 GNCIPRIYICDGDNDCLD-------NSDEDNRHQCNDRKCDEETEFTCVENKSWQRAQCI 2875
Query: 1053 PFGSKCTYDITKPMDPITCSCEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCK 874
P C D ++N HN C + C N GRC++
Sbjct: 2876 PKKWICDGD-----PDCVDGADENTTLHNCATQQPCGEDMFTCGN-GRCIN--------- 2920
Query: 873 CLPRFAGPRCDVPVQCDD------YCTNNSKCTITNGTHFECDCKPGFKGL----RCEQE 724
G CD C D +C NSK + F C FK + RC+ E
Sbjct: 2921 -----KGWICDHDNDCGDGTDEGKFC--NSKYKTCSAQEFTCQ---NFKCIRNQSRCDGE 2970
Query: 723 TKCSECSNEAKCIKK----PSGTVIC---QC-------------------PQGLGGEYCE 622
C + S+E C K+ P G C QC P + C
Sbjct: 2971 DDCGDHSDEVGCAKENITCPQGQFACTNGQCIDYNLVCNKYPDCADESDEPAHCNVDECA 3030
Query: 621 KITATSC----------HQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSSNACEN 472
K+ C + +C N GY L D A CL PG CS+
Sbjct: 3031 KVEINQCGHKCVDTLTGYYCDC-NEGYKLLADGKACADVDECLEQPGACSQHCSNTPGGF 3089
Query: 471 FCLHDGNCTLDEYFEPQ 421
+C D + Y+E Q
Sbjct: 3090 YCKCD-----ETYYERQ 3101
Score = 71.2 bits (173), Expect = 3e-10
Identities = 45/137 (32%), Positives = 65/137 (46%), Gaps = 16/137 (11%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCT---CNENEFRCQ 6403
D+ D + C+ C F C N LCIP C+ +DCA+ +DE+NCT C +N+ C
Sbjct: 98 DNSDEQGCNFPPCHHAQFRCTNALCIPYNFHCDGYHDCADKSDEANCTAIACPDNKHLCP 157
Query: 6402 SGA------CIPSKARCNHMQDCNDASD-EIGCPFRNCSALN-EF----GMTGLINCATT 6259
G CI C+ +DC D SD E C +C AL+ EF +TG +
Sbjct: 158 RGGASGTPKCILKSQLCDGKRDCEDGSDEETNCSIASCPALSCEFKCGPSLTGGVCYCKP 217
Query: 6258 SQCIHPSWK-CDGTNDC 6211
Q + P + C ++C
Sbjct: 218 GQSLAPDNRTCVDLDEC 234
Score = 67.4 bits (163), Expect = 4e-09
Identities = 48/196 (24%), Positives = 90/196 (45%), Gaps = 6/196 (3%)
Frame = -1
Query: 2448 ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIK 2269
+T D++ N+YFT ++ + + V ++ + L+ +T LAV+PIK
Sbjct: 2052 LTIDWVAGNMYFTN--------VYPHENYVEVCWLDGSNRKVLVKTTTDAPRELAVNPIK 2103
Query: 2268 RLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYW 2089
RL++W PRI A LDG LV I P + +D +YW
Sbjct: 2104 RLLYWIDYGQHPRIGKALLDG-----------SKWTPLVTSGISLPRDLTIDMQTHDIYW 2152
Query: 2088 IDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITR------QGSIHRMHK 1927
+D TI+ +S++G +R+ +R+ +L P+ + V +Y + R + S H ++
Sbjct: 2153 VDSKLDTIQKISYNGANRKIIRR-DL-PNPMGIAVYLNDVYWVDRNLMTVFKASKHSANE 2210
Query: 1926 FTGKTNKYVQKIREVS 1879
++K+R+++
Sbjct: 2211 TATSVRTNLEKLRDIA 2226
Score = 54.3 bits (129), Expect = 4e-05
Identities = 43/175 (24%), Positives = 63/175 (35%), Gaps = 10/175 (5%)
Frame = -1
Query: 4266 CSQPARCDNLCIPAN-TPDLTTSSDNFTCMCAQGFRSEGRSCVSECKPNDFVCTKTYKCI 4090
C+ +C + + N D +SD C ++ R + C P +F C + C
Sbjct: 77 CANGLKCIDAALKCNHRDDCGDNSDEQGCNFPPCHHAQFRCTNALCIPYNFHCDGYHDCA 136
Query: 4089 SSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVK 3910
E C C + +C R + T +C+ S+LCDG +
Sbjct: 137 DK------------------SDEANCTAIACPDNKHLCPRGGASGTPKCILKSQLCDGKR 178
Query: 3909 DCSGGDDEEP----AFCENFECTEAQFKCGDKKK-----CIPLTSVCDKEKDCDD 3772
DC G DEE A C C +FKCG C P S+ + C D
Sbjct: 179 DCEDGSDEETNCSIASCPALSC---EFKCGPSLTGGVCYCKPGQSLAPDNRTCVD 230
Score = 42.4 bits (98), Expect = 0.15
Identities = 62/276 (22%), Positives = 86/276 (30%), Gaps = 21/276 (7%)
Frame = -1
Query: 1407 GSCKTVPCPKDEPHCRSYSFCECDK---GWTGPHCRHKADAKVCYGHCFSGGAC-DGEGP 1240
G+ T PC E C Y C + G +G CR + C +G C D
Sbjct: 36 GARLTGPCVPKEKRCDGYLDCRTGRDEVGCSGVACR------LDQFRCANGLKCIDAALK 89
Query: 1239 LNLRCSCGDGLTGNRCQNCVGHECLNGGFCSYANSNRSLPHCICPSGFTGDHCEEYLCKD 1060
N R CGD C N C +A + CI P F HC+ Y
Sbjct: 90 CNHRDDCGDNSDEQGC---------NFPPCHHAQFRCTNALCI-PYNF---HCDGY---- 132
Query: 1059 ACPFGSKCTYDITKPMDPITCSCEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGK 880
+D D C+ + C + C GG G
Sbjct: 133 ---------HDCADKSDEANCT------------AIACPDNKHLCPRGGAS-------GT 164
Query: 879 CKCLPRFAGPRCDVPVQCDDYCTNNSKCTITNGTHFECD-------------CKPGFK-- 745
KC+ + CD C+D + C+I + C+ CKPG
Sbjct: 165 PKCILK--SQLCDGKRDCEDGSDEETNCSIASCPALSCEFKCGPSLTGGVCYCKPGQSLA 222
Query: 744 --GLRCEQETKCSECSNEAKCIKKPSGTVICQCPQG 643
C +C+E + + G+ CQC QG
Sbjct: 223 PDNRTCVDLDECAEWGHCDQLCTNTLGSYTCQCAQG 258
Score = 41.6 bits (96), Expect = 0.26
Identities = 102/490 (20%), Positives = 144/490 (28%), Gaps = 52/490 (10%)
Frame = -1
Query: 1791 CPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCGD------YFC 1630
C + C D++ + K C P F +C+ + CGD Y C
Sbjct: 3541 CDGDADCKDGSDEDPAVCFKRTCDPKTEFSCKNGRCIPQLWMCDFDNDCGDDSDEPAYMC 3600
Query: 1629 YNNAGCSPQKTCVCPPGFYGRQCEINECSETCWNGETCAVQEFGSTTNVVCHCP--SNYT 1456
+ + C PG +C C + C ++ + +CP + T
Sbjct: 3601 RQRNCTTGWQRC---PGQSNYRCIPKWLF--CDGKDDCR----DNSDELPENCPKCNPET 3651
Query: 1455 QSSCATNVC---EGVCGPRGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHKADAKVC 1285
C N C + +C C ++E C+ + EC + ++ +
Sbjct: 3652 DFKCGNNRCIPKQWMCDFADDCGDAS-DENEAVCKG-RYRECSE----------SEFRCG 3699
Query: 1284 YGHCFSGG-ACDGEGPLNLRCSCGDGLTGNRCQNCVGHECLNGGF-CSYANSNRSLPHCI 1111
G C S CD E CGD C+ G++C NG F C+ + S C
Sbjct: 3700 NGKCISSRWQCDHED------DCGDNSDEMHCE---GYQCKNGTFQCASGHCIASYFRCD 3750
Query: 1110 -------------CPSGFTGDH--------CEEYLC---KDACPFGSKCTYDITKPMDPI 1003
CP F G C LC D C C + DP
Sbjct: 3751 GDRDCRDMSDEVGCPPRFPGGRYCPESRFQCNNNLCVSLSDLCDGTDDCGDGSDE--DPS 3808
Query: 1002 TCSCEQNAAAHNTDCS-PICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQC 826
CS CS C + C C D C + CD+ Q
Sbjct: 3809 VCSDFNCDTLRRFQCSNERCVARYQICDGVDNCGDGSDENNMTLCASK--QKPCDLYTQY 3866
Query: 825 DDYCTNNSKCTITNGTHFECDCKPGFKGLRCEQETKCSECSN---EAKCIKKPSGTVICQ 655
C N + F DC L C + CSE + + C G IC
Sbjct: 3867 Q--CANKHCIERSQVCDFSDDCGDASDELGCHHTSSCSEANRGGCQQHCHNLTDGGYICT 3924
Query: 654 CPQGL-----------GGEYCEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGF 508
C G + C T HQ NG Y +C C GF
Sbjct: 3925 CYPGYIIAADNKKKCSDVDECLTRQHTCSHQCHNLNGTY-------------SCSCREGF 3971
Query: 507 KGLLCSSNAC 478
+S C
Sbjct: 3972 HLTDGASGVC 3981
>gi|16768036|gb|AAL28237.1| GH12891p [Drosophila melanogaster]
Length = 1952
Score = 659 bits (1701), Expect = 0.0
Identities = 531/1818 (29%), Positives = 775/1818 (42%), Gaps = 147/1818 (8%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCT---CNENEFRCQS 6400
DED YC+ C P F C NG CI + C+ NDC + +DE C C + EF C +
Sbjct: 39 DEDPNYCAYHSCSPNEFRCNNGRCIFKSWKCDHENDCKDGSDELGCVYPPCVDGEFTCAN 98
Query: 6399 GACIPSKARCNHMQDCND--ASDEIG--CPFRNCSALNEFGMTGLINCATTSQCIHPSWK 6232
G CIP CN + DC D SDE CP N + C T+ C+ P W
Sbjct: 99 GRCIPQAQVCNGVNDCKDNATSDETHERCPMNTTCPANH------LKCEKTNICVEPYWL 152
Query: 6231 CDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDC 6052
CDG NDC D SDE R+C + F C R C+P W CDG DC
Sbjct: 153 CDGDNDCGDNSDEDPLHC----------GQRTCPTNS-FRCPNHR-CIPATWYCDGDDDC 200
Query: 6051 ADGSDEK----NCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDE---HQC-ETE 5896
DG+DE + + C F+C++ CIP CDG DC D DE HQC + +
Sbjct: 201 GDGADEPPDYCKSEGRTCFGDLFTCDNGN-CIPRIYICDGDNDCLDNSDEDNRHQCNDRK 259
Query: 5895 CDSKGGNATFRCTNHR------CIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVP 5734
CD + F C ++ CIP W CDG DC+D A + +CA +
Sbjct: 260 CDEE---TEFTCVENKSWQRAQCIPKKWICDGDPDCVDGADE-NTTLHNCATQQPCGEDM 315
Query: 5733 SRCADETCVVACELTAVLCDGIQDCSDGFDE-KNCASLDRQCKPNEWMCDSGQCIDSGRL 5557
C + C+ +CD DC DG DE K C S + C E+ C + +CI +
Sbjct: 316 FTCGNGRCINK----GWICDHDNDCGDGTDEGKFCNSKYKTCSAQEFTCQNFKCIRNQSR 371
Query: 5556 CDASVDCVDGSDEWVEICSLSEPPRRGCPSG-WSCLLTNGTIGCLQEQQLCDGRRDCMSG 5380
CD DC D SDE C+ CP G ++C TNG C+ +C+ DC
Sbjct: 372 CDGEDDCGDHSDEVG--CAKENIT---CPQGQFAC--TNGQ--CIDYNLVCNKYPDCADE 422
Query: 5379 IDEQCDNPQGNCSSTR-NSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPK- 5206
DE C+ N C C C C++GY L D K C C +
Sbjct: 423 SDEPAHCNVDECAKVEINQCGH--KCVDTLTGYYCDCNEGYKLLA-DGKACADVDECLEQ 479
Query: 5205 -ANCSHFCIDRRDVGHQCFCAPGYILSENQKD-CRRNDTIEAEILMVYGHRLKLFTIDGH 5032
CS C + G C C Y +N + C+R D I ++ + ++ ++DGH
Sbjct: 480 PGACSQHCSNTPG-GFYCKCDETYYERQNDEHTCKRKDKIPPWLIFTNKYYVRNMSVDGH 538
Query: 5031 AKATLLSNLTNGVALDYDVKSDLVYWTDVAHDG---NKAGITSMSNQPNTYRVINSLPTK 4861
+ +L N VALD+D++ + +Y+ DV K G P VI +
Sbjct: 539 QYNLMHQDLMNVVALDFDIREEYMYFCDVTAKTIFRAKYGEADDEMPPEREAVIRH-DSH 597
Query: 4860 GIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFW 4681
G++GIA+DW+GR +Y+ DR+ + V ++ G + L G DPRAIV+ P +++
Sbjct: 598 GLEGIAIDWVGRKLYWLDRHSKNLDVSELDGSKRKTLRSGVV--DPRAIVVHPGIGYLYF 655
Query: 4680 TDWGASAHIGRMNMDGSNEQVILQ-DRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYD 4504
T W A+I +M MDGSN IL + I WPNAL++D R+Y+ DAH DYIA + +
Sbjct: 656 TSWHLQAYIAKMGMDGSNFSRILNWNDGIAWPNALSIDYFTDRIYWADAHLDYIAYADLE 715
Query: 4503 GSKRRMVLRGS-VRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMG 4327
G R VL GS V H+FAL++F+DY+YWSDW+ I R +K G N VL ++ +RP
Sbjct: 716 GRHRHTVLSGSKVPHVFALSLFDDYIYWSDWNLKAIVRANKFHGANYTVL-RNTTHRPYD 774
Query: 4326 FKIVHPSLQSMGSLKTARHPC-SQPARCDNLCIPANTPDLT---------TSSDNFTCMC 4177
I HP Q +PC + C +LC+ A P+ T + F C C
Sbjct: 775 LHINHPLRQ-----LPYTNPCGTNNGGCSHLCLIAPPPESTYLNIEGYIEEGAPIFKCAC 829
Query: 4176 AQGF--RSEGRSCVSECKPNDFVC-TKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPP 4006
F + ++CV+ C +C + KCI +W+ C P
Sbjct: 830 PNQFYLARDMKTCVANCTAGQHLCGGRDEKCIPWFWKCDGEKDCKDGSDE----PATCAP 885
Query: 4005 FPCIAGQFVCGRT--------------------AQN-------------ATAQCLYASKL 3925
C AG F C T QN ++ +C+ S
Sbjct: 886 RHCRAGTFQCKNTNCTPSATICDGVDDCGDRSDEQNCDLPCPLSDFKCKSSGRCILDSWR 945
Query: 3924 CDGVKDCSGGDDEEPAFCENFEC-TEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDE--LN 3754
CDG DC G DE+PA C C + +F C +CIP +CD + DC D SDE
Sbjct: 946 CDGDADCKDGSDEDPAVCFKRTCDPKTEFSC-KNGRCIPQLWMCDFDNDCGDDSDEPAYM 1004
Query: 3753 CEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDE-PDSCFGIGECTHE-QFQC 3580
C +C + C G + +CIPK +CDG+DDC + DE P++C +C E F+C
Sbjct: 1005 CRQRNCTTGWQRC-PGQSNYRCIPKWLFCDGKDDCRDNSDELPENC---PKCNPETDFKC 1060
Query: 3579 TSGKCIPKRRQCDGTLDCRDGSDE-----KGCKKECA---IVCDN-SCVHADDLCDGKKK 3427
+ +CIPK+ CD DC D SDE KG +EC+ C N C+ + CD +
Sbjct: 1061 GNNRCIPKQWMCDFADDCGDASDENEAVCKGRYRECSESEFRCGNGKCISSRWQCDHEDD 1120
Query: 3426 CNDGSDEDEEACVIKQLLEKENRKCGG------FACDGIVDCEDGSDEKGCPD------- 3286
C D SDE C Q + G F CDG DC D SDE GCP
Sbjct: 1121 CGDNSDEMH--CEGYQCKNGTFQCASGHCIASYFRCDGDRDCRDMSDEVGCPPRFPGGRY 1178
Query: 3285 -----LEC--HLASNKSLICDGTIDCSSGKDEN----NCHNNGESNFFQCSMQ-TIKEWQ 3142
+C +L + S +CDGT DC G DE+ + N FQCS + + +Q
Sbjct: 1179 CPESRFQCNNNLCVSLSDLCDGTDDCGDGSDEDPSVCSDFNCDTLRRFQCSNERCVARYQ 1238
Query: 3141 VCDGRWDCADGLDE-SPEMCASRKARC-FRIGYCDDKKQCLDVSTALCDGIRDCFDGSDE 2968
+CDG +C DG DE + +CAS++ C Y K C++ S +CD DC D SDE
Sbjct: 1239 ICDGVDNCGDGSDENNMTLCASKQKPCDLYTQYQCANKHCIERS-QVCDFSDDCGDASDE 1297
Query: 2967 NPI----------------HCKDMCKGKYRCT--NGRCIDVSARXXXXXXXXXXXXXXXX 2842
HC ++ G Y CT G I +
Sbjct: 1298 LGCHHTSSCSEANRGGCQQHCHNLTDGGYICTCYPGYIIAADNKKKCSDVDECLTRQHTC 1357
Query: 2841 GAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLM 2662
+CH+ N T C C G+ T C + + NG + +
Sbjct: 1358 SHQCHN-----------LNGTYSCSCREGFHLTDGASGVCRAEKEDVILLFVNGQEIRGL 1406
Query: 2661 SLENSQ----VSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSD 2494
+ S+ ++ + + + + I F D + T+ + + + +D R+K
Sbjct: 1407 NWHKSEEFAVIAAEKRIEALDYD-AQQQIVFWADSYDKTIKRSYMV--NAIDGRAKIGFA 1463
Query: 2493 GLIGSWGEEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIV 2314
+ G + TA + D++ +N+Y+TE + + VAK R+++
Sbjct: 1464 QDLNMKGGSKPTA--VAVDWLASNLYWTEMDRTGS----KPRGRVMVAKTDGRYRRSIVN 1517
Query: 2313 NSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFE 2134
S+AV+P I+W+ + P+I + +DG + L+ I
Sbjct: 1518 AGLEVPTSIAVNPQLGRIYWSDAGSAPKIEVSWMDG-----------SKRRPLITEMIRH 1566
Query: 2133 PTSMVLDFSNER-LYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT 1957
P + +D+S + +YW+D IE++ DG R+ + + + PV++D+ ++ +T
Sbjct: 1567 PAGLTIDYSQDHIIYWVDTKLNAIESMRADGSRRKAIVRGDQLRHPVSLDLFESNMFWMT 1626
Query: 1956 RQ-GSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPSN 1780
R G + R KF G+ + V V+P ++V H ++ T NPC + C
Sbjct: 1627 RDTGELVRQDKF-GRGVQVVLHRYIVNPS-GLKVYHDKRYN----TSLPNPCDNSTCSHL 1680
Query: 1779 TVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGCSP-- 1606
+ VP + P P + C E + A + C N C
Sbjct: 1681 CLLVPGGHR--CACPDASGPPPSHRSTAEVICNAAAEHPRPAPRICP--CQNGGLCKEDA 1736
Query: 1605 --QKTCVCPPGFYGRQCE 1558
+ C C F G CE
Sbjct: 1737 QGELLCECRTQFVGEHCE 1754
Score = 224 bits (570), Expect = 3e-56
Identities = 302/1271 (23%), Positives = 450/1271 (34%), Gaps = 146/1271 (11%)
Frame = -1
Query: 3999 CIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKK 3820
C A +F C +C+ CDG DC DE+P +C C+ +F+C + +
Sbjct: 9 CEASKFYC------KNGRCISRMWSCDGDDDCGDNSDEDPNYCAYHSCSPNEFRC-NNGR 61
Query: 3819 CIPLTSVCDKEKDCDDGSDELNCEITSCKPDFFACFNGTAISK----------------- 3691
CI + CD E DC DGSDEL C C F C NG I +
Sbjct: 62 CIFKSWKCDHENDCKDGSDELGCVYPPCVDGEFTCANGRCIPQAQVCNGVNDCKDNATSD 121
Query: 3690 ------------------------CIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQ 3583
C+ + CDG++DC + DE G C F+
Sbjct: 122 ETHERCPMNTTCPANHLKCEKTNICVEPYWLCDGDNDCGDNSDEDPLHCGQRTCPTNSFR 181
Query: 3582 CTSGKCIPKRRQCDGTLDCRDGSDEKG--CKKE---C---AIVCDN-SCVHADDLCDGKK 3430
C + +CIP CDG DC DG+DE CK E C CDN +C+ +CDG
Sbjct: 182 CPNHRCIPATWYCDGDDDCGDGADEPPDYCKSEGRTCFGDLFTCDNGNCIPRIYICDGDN 241
Query: 3429 KCNDGSDED--------------EEACVIKQLLEKENRKCGGFACDGIVDCEDGSDEK-- 3298
C D SDED E CV + ++ + CDG DC DG+DE
Sbjct: 242 DCLDNSDEDNRHQCNDRKCDEETEFTCVENKSWQRAQCIPKKWICDGDPDCVDGADENTT 301
Query: 3297 ---------------GCPDLECHLASNKSLICDGTIDCSSGKDE----NNCHNNGESNFF 3175
C + C NK ICD DC G DE N+ + + F
Sbjct: 302 LHNCATQQPCGEDMFTCGNGRC---INKGWICDHDNDCGDGTDEGKFCNSKYKTCSAQEF 358
Query: 3174 QC-SMQTIKEWQVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCLDVSTALCDG 2998
C + + I+ CDG DC D DE CA C + + QC+D + +C+
Sbjct: 359 TCQNFKCIRNQSRCDGEDDCGDHSDEVG--CAKENITCPQGQFACTNGQCIDYN-LVCNK 415
Query: 2997 IRDCFDGSDENPIHCK-DMC-KGKYRCTNGRCIDVSARX----XXXXXXXXXXXXXXXGA 2836
DC D SDE P HC D C K + +C+D
Sbjct: 416 YPDCADESDE-PAHCNVDECAKVEINQCGHKCVDTLTGYYCDCNEGYKLLADGKACADVD 474
Query: 2835 EC-HHFGVCAQKCWMAFNHTA---RCHCAPGYARTKNDENECEPLSKSAEMFI-TNGNRL 2671
EC G C+Q C ++T C C Y +NDE+ C+ K I TN +
Sbjct: 475 ECLEQPGACSQHC----SNTPGGFYCKCDETYYERQNDEHTCKRKDKIPPWLIFTNKYYV 530
Query: 2670 HLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDG 2491
MS++ Q +++ MN++ +DF R MY + + +D
Sbjct: 531 RNMSVDGHQYNLMHQDL---MNVV--ALDFD---IREEYMYFCDVTAKTIFRAKYGEADD 582
Query: 2490 LIGSWGE---EESTAGL--ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTR 2326
+ E + GL I D++ +Y+ + +N V D S R
Sbjct: 583 EMPPEREAVIRHDSHGLEGIAIDWVGRKLYWLDRHSKNLDV-----------SELDGSKR 631
Query: 2325 TLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVER 2146
+ + ++ V P +++T+ I +DG ++
Sbjct: 632 KTLRSGVVDPRAIVVHPGIGYLYFTSWHLQAYIAKMGMDGSNFSRILNWND--------- 682
Query: 2145 NIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIY 1966
I P ++ +D+ +R+YW D I +GR R TV + + YIY
Sbjct: 683 GIAWPNALSIDYFTDRIYWADAHLDYIAYADLEGRHRHTVLSGSKVPHVFALSLFDDYIY 742
Query: 1965 LIT-RQGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYC 1789
+I R +KF G Y + + HP + NPC ++
Sbjct: 743 WSDWNLKAIVRANKFHGA--NYTVLRNTTHRPYDLHINHPLRQ-----LPYTNPCGTNNG 795
Query: 1788 PSNTVCV---PDQD---------KNGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQC 1645
+ +C+ P + + G I KC C + K C+
Sbjct: 796 GCSHLCLIAPPPESTYLNIEGYIEEGAPIFKCACPNQFYLARDMKTCV-------ANCTA 848
Query: 1644 GDYFCYNNAGCSPQKTCVCPPGFYGRQCEINECSETCWNGETCAVQEFGSTTNVVCHCPS 1465
G + C G +K C P F+ E +C + TCA + + T C +
Sbjct: 849 GQHLC----GGRDEK---CIPWFWKCDGE-KDCKDGSDEPATCAPRHCRAGT---FQCKN 897
Query: 1464 NYTQSSCATNVCEGV--CGPRGSCKT--VPCPKDEPHCRSYSFCECDKGWTGPHCRHKAD 1297
T + + +C+GV CG R + +PCP + C+S C D W C AD
Sbjct: 898 --TNCTPSATICDGVDDCGDRSDEQNCDLPCPLSDFKCKSSGRCILD-SW---RCDGDAD 951
Query: 1296 AK--------VCYGH---------CFSGGACDGEGPLNLRCSCGDGLTGNRCQNCVGHEC 1168
K VC+ C +G + CGD + C C
Sbjct: 952 CKDGSDEDPAVCFKRTCDPKTEFSCKNGRCIPQLWMCDFDNDCGDD-SDEPAYMCRQRNC 1010
Query: 1167 LNG-GFCSYANSNRSLPHCICPSGFTGDHCEEYL--CKDACPFGSKCTYDITKPMDPITC 997
G C ++ R +P + G D C + + CP KC + C
Sbjct: 1011 TTGWQRCPGQSNYRCIPKWLFCDG--KDDCRDNSDELPENCP---KCNPETDFKCGNNRC 1065
Query: 996 SCEQNAAAHNTDCSPICQKQPNWCHNGGR-CLDTPGYPGKCKCLPRFAGPRCDVPVQCDD 820
+Q DC + C R C ++ G KC+ + +CD C D
Sbjct: 1066 IPKQWMCDFADDCGDASDENEAVCKGRYRECSESEFRCGNGKCIS--SRWQCDHEDDCGD 1123
Query: 819 YCTNNSKC---TITNGTHFEC---DCKPGFKGLRCEQETKCSECSNEAKCIKKPSGTVIC 658
++ C NGT F+C C + RC+ + C + S+E C
Sbjct: 1124 N-SDEMHCEGYQCKNGT-FQCASGHCIASY--FRCDGDRDCRDMSDEVGC---------- 1169
Query: 657 QCPQGLGGEYC 625
P+ GG YC
Sbjct: 1170 -PPRFPGGRYC 1179
Score = 149 bits (375), Expect = 1e-33
Identities = 107/323 (33%), Positives = 146/323 (45%), Gaps = 43/323 (13%)
Frame = -1
Query: 3741 SCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCI 3562
+C+ F C NG +CI + + CDG+DDC + DE + C+ +F+C +G+CI
Sbjct: 8 TCEASKFYCKNG----RCISRMWSCDGDDDCGDNSDEDPNYCAYHSCSPNEFRCNNGRCI 63
Query: 3561 PKRRQCDGTLDCRDGSDEKGCKKECAI----VCDNS-CVHADDLCDGKKKCNDG--SDED 3403
K +CD DC+DGSDE GC + C N C+ +C+G C D SDE
Sbjct: 64 FKSWKCDHENDCKDGSDELGCVYPPCVDGEFTCANGRCIPQAQVCNGVNDCKDNATSDET 123
Query: 3402 EEACVIKQLLEKENRKCGG--------FACDGIVDCEDGSDE-------KGCP--DLEC- 3277
E C + + KC + CDG DC D SDE + CP C
Sbjct: 124 HERCPMNTTCPANHLKCEKTNICVEPYWLCDGDNDCGDNSDEDPLHCGQRTCPTNSFRCP 183
Query: 3276 -HLASNKSLICDGTIDCSSGKDE--NNCHNNGESNF---FQC-SMQTIKEWQVCDGRWDC 3118
H + CDG DC G DE + C + G + F F C + I +CDG DC
Sbjct: 184 NHRCIPATWYCDGDDDCGDGADEPPDYCKSEGRTCFGDLFTCDNGNCIPRIYICDGDNDC 243
Query: 3117 ADGLDE-SPEMCASRKARCFRIGYCDDKK-----QCLDVSTALCDGIRDCFDGSDEN-PI 2959
D DE + C RK C + K QC+ +CDG DC DG+DEN +
Sbjct: 244 LDNSDEDNRHQCNDRKCDEETEFTCVENKSWQRAQCIP-KKWICDGDPDCVDGADENTTL 302
Query: 2958 H---CKDMC-KGKYRCTNGRCID 2902
H + C + + C NGRCI+
Sbjct: 303 HNCATQQPCGEDMFTCGNGRCIN 325
Score = 147 bits (370), Expect = 4e-33
Identities = 114/370 (30%), Positives = 152/370 (40%), Gaps = 24/370 (6%)
Frame = -1
Query: 6147 APRS--CDAKTQFACLATRTCMPKHWQCDGQPDCADGSDE--KNCDAKKCTSFEFSCESS 5980
APR+ C+A ++F C R C+ + W CDG DC D SDE C C+ EF C +
Sbjct: 3 APRNNTCEA-SKFYCKNGR-CISRMWSCDGDDDCGDNSDEDPNYCAYHSCSPNEFRCNNG 60
Query: 5979 KKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMD 5800
+CI KCD DC DG DE C G F C N RCIP A C+G +DC D
Sbjct: 61 -RCIFKSWKCDHENDCKDGSDELGCVYPPCVDG---EFTCANGRCIPQAQVCNGVNDCKD 116
Query: 5799 NAKSLGSDEVDCAAGRTSFHVPSRCADETCVVA----CELTAV------LCDGIQDCSDG 5650
NA TS RC T A CE T + LCDG DC D
Sbjct: 117 NA--------------TSDETHERCPMNTTCPANHLKCEKTNICVEPYWLCDGDNDCGDN 162
Query: 5649 FDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASVDCVDGSDEWVEICSLSEPPRRGCP 5470
DE R C N + C + +CI + CD DC DG+DE + C + R C
Sbjct: 163 SDEDPLHCGQRTCPTNSFRCPNHRCIPATWYCDGDDDCGDGADEPPDYC---KSEGRTC- 218
Query: 5469 SGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSSTRNSCDQTWNCQRHAG 5290
+ L T C+ +CDG DC+ DE DN + C+ + + + C +
Sbjct: 219 --FGDLFTCDNGNCIPRIYICDGDNDCLDNSDE--DN-RHQCNDRKCDEETEFTCVENKS 273
Query: 5289 FESCSCDDGYHLSPYDKKTCLRSPSC----PKANCSHFCIDRRDVGHQCF-CAPGYILS- 5128
++ C K C P C + H C ++ G F C G ++
Sbjct: 274 WQRAQCIP-------KKWICDGDPDCVDGADENTTLHNCATQQPCGEDMFTCGNGRCINK 326
Query: 5127 ----ENQKDC 5110
++ DC
Sbjct: 327 GWICDHDNDC 336
Score = 110 bits (276), Expect = 4e-22
Identities = 71/265 (26%), Positives = 104/265 (38%), Gaps = 27/265 (10%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCT--------CNEN 6418
D+ D +C C+ G F C +G CI C+ DC + +DE C C E+
Sbjct: 1123 DNSDEMHCEGYQCKNGTFQCASGHCIASYFRCDGDRDCRDMSDEVGCPPRFPGGRYCPES 1182
Query: 6417 EFRCQSGACIPSKARCNHMQDCNDASDE--IGCPFRNCSALNEFGMTGLINCATTSQCIH 6244
F+C + C+ C+ DC D SDE C NC L F + +C+
Sbjct: 1183 RFQCNNNLCVSLSDLCDGTDDCGDGSDEDPSVCSDFNCDTLRRFQ-------CSNERCVA 1235
Query: 6243 PSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDG 6064
CDG ++C DGSDE + + S + CD TQ+ C A + C+ + CD
Sbjct: 1236 RYQICDGVDNCGDGSDENNMTL-------CASKQKPCDLYTQYQC-ANKHCIERSQVCDF 1287
Query: 6063 QPDCADGSDEKNCDAKKCTSFEFSCESSKKCIPLEQ-------------KCDGRRDCPDG 5923
DC D SDE C S + C L D ++ C D
Sbjct: 1288 SDDCGDASDELGCHHTSSCSEANRGGCQQHCHNLTDGGYICTCYPGYIIAADNKKKCSDV 1347
Query: 5922 ED----EHQCETECDSKGGNATFRC 5860
++ +H C +C + G + C
Sbjct: 1348 DECLTRQHTCSHQCHNLNGTYSCSC 1372
Score = 54.3 bits (129), Expect = 4e-05
Identities = 47/190 (24%), Positives = 72/190 (37%), Gaps = 12/190 (6%)
Frame = -1
Query: 5634 CASLDRQCKPNEWMCDSGQCIDSGRLCDASVDCVDGSDEWVEICSLSEPPRRGC-PSGWS 5458
CA + C+ +++ C +G+CI CD DC D SDE C+ C P+ +
Sbjct: 2 CAPRNNTCEASKFYCKNGRCISRMWSCDGDDDCGDNSDEDPNYCAY-----HSCSPNEFR 56
Query: 5457 CLLTNGTIGCLQEQQLCDGRRDCMSGIDE-QCDNP----------QGNCSSTRNSCDQTW 5311
C NG C+ + CD DC G DE C P G C C+
Sbjct: 57 C--NNGR--CIFKSWKCDHENDCKDGSDELGCVYPPCVDGEFTCANGRCIPQAQVCNGVN 112
Query: 5310 NCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPKANCSHFCIDRRDVGHQCFCAPGYIL 5131
+C+ +A S + C + +CP +H ++ ++ C Y L
Sbjct: 113 DCKDNA------------TSDETHERCPMNTTCP---ANHLKCEKTNI-----CVEPYWL 152
Query: 5130 SENQKDCRRN 5101
+ DC N
Sbjct: 153 CDGDNDCGDN 162
Score = 50.8 bits (120), Expect = 4e-04
Identities = 115/542 (21%), Positives = 170/542 (31%), Gaps = 85/542 (15%)
Frame = -1
Query: 1791 CPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGC 1612
C + C + D++ C P F + +C+ K + C D
Sbjct: 28 CDGDDDCGDNSDEDPNYCAYHSCSPNEF-RCNNGRCIFKSWKCDHENDCKDG-------- 78
Query: 1611 SPQKTCVCPPGFYGR-QCEINEC---SETCWNGETCAVQEFGSTTNVVCH----CPSNYT 1456
S + CV PP G C C ++ C C T+ C CP+N+
Sbjct: 79 SDELGCVYPPCVDGEFTCANGRCIPQAQVCNGVNDCKDNATSDETHERCPMNTTCPANHL 138
Query: 1455 QSSCATNVC---------EGVCGPRGS-----CKTVPCPKDEPHCRSYS------FCE-- 1342
+ TN+C + CG C CP + C ++ +C+
Sbjct: 139 KCE-KTNICVEPYWLCDGDNDCGDNSDEDPLHCGQRTCPTNSFRCPNHRCIPATWYCDGD 197
Query: 1341 --CDKGWTGPHCRHKADAKVCYGHCFSGGACDGEGPLNLRCSCGDGLTGNRCQNCVG-HE 1171
C G P K++ + C+G F+ C +G R C G ++
Sbjct: 198 DDCGDGADEPPDYCKSEGRTCFGDLFT---------------CDNGNCIPRIYICDGDND 242
Query: 1170 CLNGGFCSYANSNRSLPH------CICPSGFTGDHCEEYLCKDACPFGSKCTYDITKPMD 1009
CL+ NS+ H C + FT + + P C D
Sbjct: 243 CLD-------NSDEDNRHQCNDRKCDEETEFTCVENKSWQRAQCIPKKWICDGD-----P 290
Query: 1008 PITCSCEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQ 829
++N HN C + C NG RC++ G CD
Sbjct: 291 DCVDGADENTTLHNCATQQPCGEDMFTCGNG-RCINK--------------GWICDHDND 335
Query: 828 CDD------YCTNNSKCTITNGTHFECDCKPGFKGLR----CEQETKCSECSNEAKCIKK 679
C D +C NSK + F C FK +R C+ E C + S+E C K+
Sbjct: 336 CGDGTDEGKFC--NSKYKTCSAQEFTCQ---NFKCIRNQSRCDGEDDCGDHSDEVGCAKE 390
Query: 678 ----PSGTVIC---QC-------------------PQGLGGEYCEKITATSC-------- 601
P G C QC P + C K+ C
Sbjct: 391 NITCPQGQFACTNGQCIDYNLVCNKYPDCADESDEPAHCNVDECAKVEINQCGHKCVDTL 450
Query: 600 --HQLECKNGGYCLKPDPSANRTSPTCLCSPGFKGLLCSSNACENFCLHDGNCTLDEYFE 427
+ +C N GY L D A CL PG CS+ +C D + Y+E
Sbjct: 451 TGYYCDC-NEGYKLLADGKACADVDECLEQPGACSQHCSNTPGGFYCKCD-----ETYYE 504
Query: 426 PQ 421
Q
Sbjct: 505 RQ 506
Score = 41.6 bits (96), Expect = 0.26
Identities = 102/490 (20%), Positives = 144/490 (28%), Gaps = 52/490 (10%)
Frame = -1
Query: 1791 CPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCGD------YFC 1630
C + C D++ + K C P F +C+ + CGD Y C
Sbjct: 946 CDGDADCKDGSDEDPAVCFKRTCDPKTEFSCKNGRCIPQLWMCDFDNDCGDDSDEPAYMC 1005
Query: 1629 YNNAGCSPQKTCVCPPGFYGRQCEINECSETCWNGETCAVQEFGSTTNVVCHCP--SNYT 1456
+ + C PG +C C + C ++ + +CP + T
Sbjct: 1006 RQRNCTTGWQRC---PGQSNYRCIPKWLF--CDGKDDCR----DNSDELPENCPKCNPET 1056
Query: 1455 QSSCATNVC---EGVCGPRGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHKADAKVC 1285
C N C + +C C ++E C+ + EC + ++ +
Sbjct: 1057 DFKCGNNRCIPKQWMCDFADDCGDAS-DENEAVCKG-RYRECSE----------SEFRCG 1104
Query: 1284 YGHCFSGG-ACDGEGPLNLRCSCGDGLTGNRCQNCVGHECLNGGF-CSYANSNRSLPHCI 1111
G C S CD E CGD C+ G++C NG F C+ + S C
Sbjct: 1105 NGKCISSRWQCDHED------DCGDNSDEMHCE---GYQCKNGTFQCASGHCIASYFRCD 1155
Query: 1110 -------------CPSGFTGDH--------CEEYLC---KDACPFGSKCTYDITKPMDPI 1003
CP F G C LC D C C + DP
Sbjct: 1156 GDRDCRDMSDEVGCPPRFPGGRYCPESRFQCNNNLCVSLSDLCDGTDDCGDGSDE--DPS 1213
Query: 1002 TCSCEQNAAAHNTDCS-PICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQC 826
CS CS C + C C D C + CD+ Q
Sbjct: 1214 VCSDFNCDTLRRFQCSNERCVARYQICDGVDNCGDGSDENNMTLCASK--QKPCDLYTQY 1271
Query: 825 DDYCTNNSKCTITNGTHFECDCKPGFKGLRCEQETKCSECSN---EAKCIKKPSGTVICQ 655
C N + F DC L C + CSE + + C G IC
Sbjct: 1272 Q--CANKHCIERSQVCDFSDDCGDASDELGCHHTSSCSEANRGGCQQHCHNLTDGGYICT 1329
Query: 654 CPQGL-----------GGEYCEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGF 508
C G + C T HQ NG Y +C C GF
Sbjct: 1330 CYPGYIIAADNKKKCSDVDECLTRQHTCSHQCHNLNGTY-------------SCSCREGF 1376
Query: 507 KGLLCSSNAC 478
+S C
Sbjct: 1377 HLTDGASGVC 1386
>gi|31203671|ref|XP_310784.1| ENSANGP00000014849 [Anopheles gambiae]
gi|30177963|gb|EAA06237.2| ENSANGP00000014849 [Anopheles gambiae str.
PEST]
Length = 4569
Score = 655 bits (1690), Expect = 0.0
Identities = 538/1826 (29%), Positives = 785/1826 (42%), Gaps = 154/1826 (8%)
Frame = -1
Query: 6570 DEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCT---CNENEFRCQS 6400
DED YC+ C F C NG CI + C+ NDC + +DE C+ C + EF C +
Sbjct: 2642 DEDVNYCAFHSCAANEFRCANGRCIFKSWKCDHENDCKDGSDEEGCSYPPCVDGEFTCAN 2701
Query: 6399 GACIPSKARCNHMQDCND--ASDEIG--CPFRNCSALNEFGMTGLINCATTSQCIHPSWK 6232
G CIP CN + DC D SDE CP N + C T+ C+ P W
Sbjct: 2702 GRCIPQAQVCNGVNDCKDNGTSDETHERCPTNTTCPPNH------LKCDRTNICVEPYWL 2755
Query: 6231 CDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDC 6052
CDG NDC D SDE A R+C + F C R C+P W CDG DC
Sbjct: 2756 CDGDNDCGDNSDENPLHC----------AQRTCP-QNSFRCPNHR-CIPATWYCDGDDDC 2803
Query: 6051 ADGSDEK----NCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDE---HQC-ETE 5896
DG+DE + + C F+C++ CIP CDG DC D DE HQC + +
Sbjct: 2804 GDGADEPPEYCKSEGRTCFGDLFTCDNGN-CIPRIYICDGDNDCLDNSDEDNRHQCNDRK 2862
Query: 5895 CDSKGGNATFRCTNHR------CIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVP 5734
CD + F C ++ CIP W CDG DC+D G+DE T H P
Sbjct: 2863 CDE---DTEFTCHENKAWARAQCIPKKWICDGDPDCVD-----GADE-----NTTLQHCP 2909
Query: 5733 SR--CADETCVVA---CELTAVLCDGIQDCSDGFDE-KNCASLDRQCKPNEWMCDSGQCI 5572
S C ++ A C +CD DC DG DE KNC S + C P E+ C + +CI
Sbjct: 2910 SPQPCGEDMFTCANGRCINQGWVCDHDNDCGDGSDEGKNCNSQYKTCTPQEFTCQNFKCI 2969
Query: 5571 DSGRLCDASVDCVDGSDEWVEICSLSEPPRRGCPSG-WSCLLTNGTIGCLQEQQLCDGRR 5395
+ CD DC D SDE + C G ++C NG C+ +C+
Sbjct: 2970 RNQYRCDGEDDCGDHSDEVG-----CKKDNATCAEGKFTC--NNGQ--CIDYHLVCNKVP 3020
Query: 5394 DCMSGIDEQCDNPQGNCSSTR-NSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSP 5218
DC DE C+ + C C C C+ GY L D K C
Sbjct: 3021 DCTDESDEPLHCNVDECAKVEIHRCGH--KCVDTLTSYYCDCNQGYKLLE-DGKACADID 3077
Query: 5217 SCPKAN--CSHFCIDRRDVGHQCFCAPGYILSENQKD-CRRNDTIEAEILMVYGHRLKLF 5047
C + CS C + G+ C C Y +N + C+R D + ++ + ++
Sbjct: 3078 ECIETPGVCSQHCSNTPG-GYYCKCDERYYERQNDEHTCKRKDDTKPWLIFSNKYYVRNM 3136
Query: 5046 TIDGHAKATLLSNLTNGVALDYDVKSDLVYWTDV-AHDGNKAGITSMSNQPNTYRVINSL 4870
+ DGH + +L N VA+D+D++ +Y+ DV A K+ S+ + R+ +
Sbjct: 3137 STDGHQYNLIHQDLMNVVAIDFDMQQHEMYFCDVTAKTIFKSSFGSLVE--DGVRIEKTP 3194
Query: 4869 PTK----GIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDP 4702
K G++GIA+DW+GR +Y+ DR+ + V ++ G + L G DPRAIV+ P
Sbjct: 3195 VIKHDSHGLEGIAIDWVGRKLYWLDRHSKNLDVAELDGTRRKTLRSGVV--DPRAIVVHP 3252
Query: 4701 LQALVFWTDWGASAHIGRMNMDGSN-EQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDY 4525
+++T W A+I +M MDGSN +++ + I WPNAL +D R+Y+ DAH DY
Sbjct: 3253 GIGYLYFTSWHLQAYIAKMGMDGSNFTRILTWEDDIAWPNALTIDYFTDRIYWADAHLDY 3312
Query: 4524 IASCNYDGSKRRMVLRGS-VRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQD 4348
IA + +G R +VL G+ V H+FAL++F+D +YW+DW+ I R +K TG N V +++
Sbjct: 3313 IAFADLEGRHRHVVLSGARVPHVFALSIFDDSLYWTDWNLKAILRANKFTGANYTV-VRN 3371
Query: 4347 KQYRPMGFKIVHPSLQSMGSLKTARHPC-SQPARCDNLCIPANTPD---------LTTSS 4198
+RP I HP Q +PC + C +LC+ A + L +
Sbjct: 3372 TTHRPYDVHISHPLRQI-----PFPNPCGTTNGGCSHLCLLAPPLESTYLNVEGYLEEGA 3426
Query: 4197 DNFTCMCAQGF--RSEGRSCVSECKPNDFVC-TKTYKCISSWWRXXXXXXXXXXXXXGYF 4027
++ C C F + ++C++ C C KCI +W+
Sbjct: 3427 PSYRCACPNQFYLARDQKTCIANCTSGQHRCGGDDEKCIPWFWKCDGEPDCKDRSDE--- 3483
Query: 4026 VEGVCPPFPCIAGQFVCGR--------------------TAQN-------------ATAQ 3946
CP C AG F CG QN ++ +
Sbjct: 3484 -PASCPARHCRAGTFQCGNGNCTPSTTICDGTDDCGDGTDEQNCDLPCPVSDFKCKSSGR 3542
Query: 3945 CLYASKLCDGVKDCSGGDDEEPAFCENFEC-TEAQFKCGDKKKCIPLTSVCDKEKDCDDG 3769
C+ S CDG DC G DE+P C C E +F C +CIP +CD + DC D
Sbjct: 3543 CILDSWKCDGDADCKDGSDEDPEICHKRTCDPETEFSC-KNGRCIPKLWMCDFDNDCGDD 3601
Query: 3768 SDE--LNCEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDE-PDSCFGIGECT 3598
SDE C +C + C G + +CIPK +CDG+DDC + DE P++C +C
Sbjct: 3602 SDEPAYMCRQRNCTTGWSRC-PGQSNYRCIPKWLFCDGKDDCRDKSDELPENC---PQCN 3657
Query: 3597 HE-QFQCTSGKCIPKRRQCDGTLDCRDGSDE-----KGCKKECA---IVCDN-SCVHADD 3448
E F+C + +CIP++ CD DC DGSDE KG +EC+ CDN C+ +
Sbjct: 3658 QETDFKCNNNRCIPRQWMCDFADDCGDGSDESETQCKGKYRECSESEFRCDNGKCISSRW 3717
Query: 3447 LCDGKKKCNDGSDE--DEEACVIKQLLEKENRKC--GGFACDGIVDCEDGSDEKGCPD-- 3286
CD + C D SDE E + ++ C F CDG DC D SDE GCP
Sbjct: 3718 RCDHEDDCGDNSDEYGCEGFQCKNGTFQCKSGHCIAAYFRCDGDRDCRDMSDEIGCPPRF 3777
Query: 3285 ----------LEC--HLASNKSLICDGTIDCSSGKDE--NNCHNNGESNF--FQC-SMQT 3157
+C +L S +CDGT DC DE + C N FQC + +
Sbjct: 3778 PGGRYCPESRFQCANNLCVLPSDLCDGTDDCGDNSDEAASVCTNFNCDTLRRFQCANHRC 3837
Query: 3156 IKEWQVCDGRWDCADGLDE-SPEMCASRKARC-FRIGYCDDKKQCLDVSTALCDGIRDCF 2983
+ +Q+CDG +C DG DE + +CA+R+ C Y K+C+D +CD DC
Sbjct: 3838 VARYQICDGVDNCGDGSDENNMTLCAARQKPCDLYTQYQCANKKCID-RAQVCDYADDCG 3896
Query: 2982 DGSDENPIH----CKDMCKG--KYRCTNGRCIDVSARXXXXXXXXXXXXXXXXGAEC-HH 2824
DGSDE H C + KG ++ C N + A EC
Sbjct: 3897 DGSDELGCHRTASCSALNKGGCEHHCVNLTDGYICACYAGFIIDASNKKRCTDIDECATG 3956
Query: 2823 FGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMS-LENS 2647
C+ C N T C C G+ + C+ L + ++ G + +N
Sbjct: 3957 THGCSHLC-TNLNGTYECGCREGFRLSDRVSGVCKALKGEPLLVLSGGPEIRAYEPAQNR 4015
Query: 2646 QVSVLRPVFNIK-MNLIP-GGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWG 2473
Q V+ I+ ++ P + F D + T+ + + D + D + G
Sbjct: 4016 QFDVIAGEKRIEALDYNPESQMIFWTDSYDKTIKRSYMVNAMNGDAKVGYAQD--LNMKG 4073
Query: 2472 EEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTIN 2293
+ TA + D++ +N+Y+ E+ + I VAK R L+
Sbjct: 4074 GTKPTA--LAVDWVADNLYWAETDRTGS----KPRGRIMVAKTDGRYRRALVQAGLEVPT 4127
Query: 2292 SLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLD 2113
++AVDP +FW + P+I + +DG + ++ I P + +D
Sbjct: 4128 AIAVDPQLGRMFWADAGSAPKIEVSWMDG-----------SKRRPIITEAIRHPAGLTVD 4176
Query: 2112 FSNER-LYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITRQ-GSIH 1939
+S + +YW+D TIE + DG RRTV K +L PV++DV +Y +TR G +
Sbjct: 4177 YSQDHAVYWVDTKLNTIEVMKPDGTMRRTVLKGDLLKHPVSLDVFESSLYWVTRDTGELL 4236
Query: 1938 RMHKFTGKTNKYVQKIREVSPRIQIRVAHPAK----HTVSHITHQKNPCQSDYCPSNTVC 1771
R KF R V +Q +A+P+ H + + T NPC + C +
Sbjct: 4237 RQDKFG----------RGVQVTVQRNLANPSSIKVYHELRYNTTLNNPCYRNPCSHLCLL 4286
Query: 1770 VPDQDKNGILIPKCLCG----PGRFFEVSTKKCMQLREKDQEASQCGDYFCYNNAGC--- 1612
VP +C C P + C E+ + A + C N C
Sbjct: 4287 VPGG-------RRCSCPDNTVPTSHRSTAEVVCDAPAERPRPAPRVCP--CQNGGLCKEA 4337
Query: 1611 -------SPQKTCVCPPGFYGRQCEI 1555
S + CVC P F G CE+
Sbjct: 4338 DAGPGAPSSELVCVCLPEFSGTHCEV 4363
Score = 391 bits (1005), Expect = e-106
Identities = 258/814 (31%), Positives = 382/814 (46%), Gaps = 18/814 (2%)
Frame = -1
Query: 6522 FNCGNGLCIPEQKVCNRINDCANFADES-NCT---CNENEFRCQSGACIPSKARCNHMQD 6355
F C N CIP+ +C+ +DC + +DE NCT C NEF+C+SG CIP RC+ D
Sbjct: 944 FTCNNQRCIPKSWICDGDDDCLDNSDEEQNCTKPTCGTNEFQCKSGRCIPLNFRCDQEND 1003
Query: 6354 CNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDGTNDCYDGSDEKDCFVE 6175
C D SDE C C+A ++F +CI WKCD NDC DGSDE
Sbjct: 1004 CGDHSDEFECGNVTCAA-SQFA-------CENGRCIPNIWKCDSENDCGDGSDE------ 1049
Query: 6174 FDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADGSDEKNCDAKKCTSFEF 5995
G A ++C A QF C T C+P+ W CDG DC D DEK+C C + +F
Sbjct: 1050 -----GPFCAEKTC-AYFQFTCPRTGHCIPQSWVCDGDDDCFDKQDEKDCPPITCLANQF 1103
Query: 5994 SCESSKKCIPLEQKCDGRRDCPDGEDEHQCET-ECDSKGGNATFRC-TNHRCIPMAWRCD 5821
C ++C+ KCDG DC DG DE C T E + FRC ++ CIP+AW CD
Sbjct: 1104 KCADLRQCVEEPYKCDGIPDCNDGSDELGCPTMEPNQCNLEKHFRCRSSGVCIPIAWHCD 1163
Query: 5820 GTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACELTAVLCDGIQDCSDGFDE 5641
G++DC D++ ++ C G F+ +CA+ CV A +CDG DC DG DE
Sbjct: 1164 GSNDCDDHSDEEDCSKITCPNG---FY---KCANAKCV----FKAYICDGKDDCGDGSDE 1213
Query: 5640 K---NCASLDRQCKPNEWMCD--SGQCIDSGRLCDASVDCVDGSDEWVEICSLSEPPRRG 5476
C + ++C +W C + +C++ +CD DC +G+DE
Sbjct: 1214 SVEHACVTPPQRCAHGQWACPGVTERCVNLTSVCDDVPDCPNGADE-------------- 1259
Query: 5475 CPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSSTRNSCDQTWNCQRH 5296
G C L QC + G CS+ CQ+
Sbjct: 1260 ---GLGCDLA-------------------------QCQHQTGLCSN---------GCQKT 1282
Query: 5295 AGFESCSCDDGYHLSPYDKKTCLRSPSC-PKANCSHFCIDRRDVGHQCFCAPGYILSENQ 5119
C C G L+P D TC C P CS C + + + C C GY+L N+
Sbjct: 1283 PLGALCICPPGEELAP-DNFTCKDLNECDPPGLCSQRCTNTKG-SYFCSCVDGYVLEPNK 1340
Query: 5118 KDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLTNGVALDYDVKSDLVYWTDVAH 4939
C+ + A +++ H + + + + + N VA ++ + ++W+D+
Sbjct: 1341 HTCKAVNHPAAFLIISNRHSILVADLKEQGLERVPIIVENVVATASNMHTGTIFWSDM-- 1398
Query: 4938 DGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFN 4759
K S ++ + I S ++G+A DW+G+N+Y+ D + I V G N
Sbjct: 1399 ---KLKKISRLDRGMEPQEIISTGLDLVEGLAYDWIGQNLYWLDSKLNTIEVAHENGS-N 1454
Query: 4758 RILLKGTPLNDPRAIVLDPLQAL--VFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPN 4585
R++L + PR + LDP +FWTDWG + I R+ MDG+ + I+ + I WPN
Sbjct: 1455 RLVLVRENITQPRGMCLDPSPTAKWLFWTDWGENPRIERIGMDGTMRETIVSTK-IYWPN 1513
Query: 4584 ALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRGS--VRHIFALAVFEDYVYWSDWH 4411
L +D QR+YF D+ D+I C Y+G+ R+ VL S + H +L++FED +YW+D
Sbjct: 1514 GLTLDVATQRVYFADSKLDFIDFCYYNGTGRQQVLAASHYLLHAHSLSLFEDTLYWTDRQ 1573
Query: 4410 NHTIERVHKITGTNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPARCDNLCI 4231
+ + HK GTN+ V + +P+ + HPSLQ M PC + A C ++C+
Sbjct: 1574 LNRVLSAHKYRGTNQTV-VSHLISQPLSVHVHHPSLQPM-----YESPCKR-AACQHVCL 1626
Query: 4230 PANTPDLTTSSDNFTCMCAQGFR--SEGRSCVSE 4135
+ + + C C G+R EGR C E
Sbjct: 1627 LS-----PSEPAGYACKCRPGYRLLPEGR-CTEE 1654
Score = 343 bits (881), Expect = 2e-92
Identities = 321/1235 (25%), Positives = 519/1235 (41%), Gaps = 73/1235 (5%)
Frame = -1
Query: 5199 CSHFCIDRR------DVGHQCFCAPGYILSENQKDCR--RNDTIEAEILMVYGHRLKLFT 5044
CS C+ +G++C C G+ LS++ +C R + ++ + G L
Sbjct: 560 CSQMCVVTAVQGAPSGLGYRCACHTGWQLSKDLMNCHLVRQFLMYSQQRFIKGKVLDP-V 618
Query: 5043 IDGHAKATL--LSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQPNTYRVINSL 4870
I+G + A L +S V LD+D + +Y++DV D I + ++ +
Sbjct: 619 IEGFSDAILPVVSRRARFVGLDFDAVDEHIYYSDVLQDV----IYRVHRNGTGREIVLAS 674
Query: 4869 PTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGR-FNRILLKGTPLNDPRAIVLDPLQA 4693
+G++G+AVDW+ +N+YY D + V R + R LLK L PRAIV+ P +
Sbjct: 675 QNEGVEGLAVDWVSKNLYYIDSRKGTLNVLSTRNTSYRRTLLKN--LKRPRAIVVHPNRG 732
Query: 4692 LVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASC 4513
+++++W A+I R N DGS ++ ++ T+ WPN L++D R+Y+ DA D++
Sbjct: 733 YIYFSEWDRPANISRANADGSG-LIVFRNLTLGWPNGLSIDFREDRVYWCDALLDHVQHA 791
Query: 4512 NYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQ-YR 4336
N DG+ R V +RH F++ + E+++Y +DW I R++K+ G ++++++ Q R
Sbjct: 792 NLDGTDVRTVNSRLIRHPFSIVIHEEWMYITDWRLDAIVRLNKLNGEQEEIMVREPQTNR 851
Query: 4335 PMGFKIVHPSLQSMGSLKTARHPCS-QPARCDNLC--IPAN-TPDLTTSSDN-------- 4192
G K+ +QS+ A PC C+ LC +P N T D +S
Sbjct: 852 LYGVKVYSHGVQSI----DASQPCGVNNGGCEKLCFALPRNDTEDAAAASAGGPTSPRLV 907
Query: 4191 FTCMCAQGFR--SEGRSCVSECKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEG 4018
C C G R +GRSC+S+ PN C ++W
Sbjct: 908 VKCGCPYGERLGDDGRSCLSD--PN--AEPPVQACPNTW--------------------- 942
Query: 4017 VCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFK 3838
F C +C+ S +CDG DC DEE C C +F+
Sbjct: 943 ----------DFTCN------NQRCIPKSWICDGDDDCLDNSDEEQN-CTKPTCGTNEFQ 985
Query: 3837 CGDKKKCIPLTSVCDKEKDCDDGSDELNCEITSCKPDFFACFNGTAISKCIPKEFYCDGE 3658
C +CIPL CD+E DC D SDE C +C FAC NG +CIP + CD E
Sbjct: 986 C-KSGRCIPLNFRCDQENDCGDHSDEFECGNVTCAASQFACENG----RCIPNIWKCDSE 1040
Query: 3657 DDCPEGQDEPDSCFGIGECTHEQFQC-TSGKCIPKRRQCDGTLDCRDGSDEKGC------ 3499
+DC +G DE C C + QF C +G CIP+ CDG DC D DEK C
Sbjct: 1041 NDCGDGSDEGPFC-AEKTCAYFQFTCPRTGHCIPQSWVCDGDDDCFDKQDEKDCPPITCL 1099
Query: 3498 --KKECAIVCDNSCVHADDLCDGKKKCNDGSDE------DEEACVI-KQLLEKENRKCGG 3346
+ +CA + CV CDG CNDGSDE + C + K + + C
Sbjct: 1100 ANQFKCADL--RQCVEEPYKCDGIPDCNDGSDELGCPTMEPNQCNLEKHFRCRSSGVCIP 1157
Query: 3345 FA--CDGIVDCEDGSDEKGCPDLEC----HLASN-----KSLICDGTIDCSSGKDENNCH 3199
A CDG DC+D SDE+ C + C + +N K+ ICDG DC G DE+ H
Sbjct: 1158 IAWHCDGSNDCDDHSDEEDCSKITCPNGFYKCANAKCVFKAYICDGKDDCGDGSDESVEH 1217
Query: 3198 NNGESNFFQCSMQTIKEWQVC-DGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCLD 3022
+ Q C G+W C G+ E RC +
Sbjct: 1218 ------------ACVTPPQRCAHGQWAC-PGVTE----------RCVNL----------- 1243
Query: 3021 VSTALCDGIRDCFDGSDENPIHCKDMCKGKYR---CTNG--------RCIDVSARXXXXX 2875
T++CD + DC +G+DE + C D+ + +++ C+NG CI
Sbjct: 1244 --TSVCDDVPDCPNGADEG-LGC-DLAQCQHQTGLCSNGCQKTPLGALCICPPGEELAPD 1299
Query: 2874 XXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEM 2695
EC G+C+Q+C + C C GY N ++ C+ ++ A
Sbjct: 1300 NFTCKDLN-----ECDPPGLCSQRCTNT-KGSYFCSCVDGYVLEPN-KHTCKAVNHPAAF 1352
Query: 2694 FITNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDI 2515
I + L++ Q P+ ++ + ++ T+ ++ D+
Sbjct: 1353 LIISNRHSILVADLKEQGLERVPI------IVENVVATASNMHTGTIFWS--------DM 1398
Query: 2514 RSKKWSDGLIGSWGEEESTAGL-----ITYDFMHNNVYFTESSEQNRGVLFDRQAN-IYV 2353
+ KK S G +E + GL + YD++ N+Y+ +S V + +N + +
Sbjct: 1399 KLKKISRLDRGMEPQEIISTGLDLVEGLAYDWIGQNLYWLDSKLNTIEVAHENGSNRLVL 1458
Query: 2352 AKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGS 2173
+ T R + ++ + P + +FWT PRI +DG
Sbjct: 1459 VRENITQPRGMCLDPS---------PTAKWLFWTDWGENPRIERIGMDG----------- 1498
Query: 2172 QPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPV- 1996
+ +V I+ P + LD + +R+Y+ D I+ ++G R+ V
Sbjct: 1499 TMRETIVSTKIYWPNGLTLDVATQRVYFADSKLDFIDFCYYNGTGRQQVLAASHYLLHAH 1558
Query: 1995 TMDVLGGYIYLITRQ-GSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITH 1819
++ + +Y RQ + HK+ G V + +S + + V HP+ +
Sbjct: 1559 SLSLFEDTLYWTDRQLNRVLSAHKYRGTNQTVVSHL--ISQPLSVHVHHPSLQPM----- 1611
Query: 1818 QKNPCQSDYCPSNTVCVPDQDKNGILIPKCLCGPG 1714
++PC+ C + P + C C PG
Sbjct: 1612 YESPCKRAACQHVCLLSPSEPAG----YACKCRPG 1642
Score = 331 bits (849), Expect = 1e-88
Identities = 422/1727 (24%), Positives = 661/1727 (37%), Gaps = 158/1727 (9%)
Frame = -1
Query: 5244 DKKTCLRSPSCPKANCSHFCID-----RRDVGHQCFCAPGYILSENQKDCRRNDTIEAEI 5080
D CLR + C C + +C CA G L + + C D
Sbjct: 2250 DANPCLRLGN---GGCDQLCFALPPDYSQKPSFRCDCAVGR-LGADGRHCELTDEY---- 2301
Query: 5079 LMVYGHRLKLFTIDGHAKATLL-----SNLTNGVALDYDVKSDLVYWTDVAHDGNKAGIT 4915
+++ R ++ ID +T + +NLTN V LD+D + +++T + A +
Sbjct: 2302 -IIFATRTEIRAIDLDPASTNVPFAPVANLTNVVGLDFDYADNKLFFTQIRPWSKIAWLR 2360
Query: 4914 SMSNQPNTYRVINSLPTKGI--DGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKG 4741
++P+ I + T+GI +GIA DW R IY+TD ++++I + G ++ +
Sbjct: 2361 G--DKPDA-AAITPVMTRGINPEGIAYDWTQRKIYWTDSSNNSIYAMNTDGTELVMIAR- 2416
Query: 4740 TPLNDPRAIVLDPLQALVFWTDWG---ASAHIGRMNMDGSNEQVILQDRTIRWPNALAVD 4570
+ PRAIVLDP +++TDWG S I R M GS ++ I+ DR + P+ LA+D
Sbjct: 2417 --VERPRAIVLDPCNGTLYFTDWGRFGTSGKIFRTTMAGSLKRAII-DRDLSQPSGLAID 2473
Query: 4569 APAQRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERV 4390
+ LY+ DA R+ I DG R +++ ++ + FA+ VF +Y+YW+D + R
Sbjct: 2474 YDDRMLYWTDAVREKIERSQLDGRNREVLISATI-YPFAITVFRNYIYWTDLQLRGVYRA 2532
Query: 4389 HKITGTNRKVLIQDKQYRPMGFKI---------VHPSLQSMGSLKTARHPCSQ---PARC 4246
K TG +++ + P I +P LQ+ G + HP + +C
Sbjct: 2533 EKHTGAGVHEMVKRLEDSPRDIHIYSATRQQCQANPCLQNNGGCAQSCHPGANGKPECKC 2592
Query: 4245 DNLCIPANTPDL------TTSSDNFTCM----------------CAQGFRSEGRSCV-SE 4135
D+ P N + T + F C C G + C
Sbjct: 2593 DDTTKPVNEGRMCAPKNHTCDASKFYCQNGKCISRMWSCDGDDDCGDGSDEDVNYCAFHS 2652
Query: 4134 CKPNDFVCTKTYKCISSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNA 3955
C N+F C +CI W+ E C PC+ G+F C A
Sbjct: 2653 CAANEFRCANG-RCIFKSWKCDHENDCKDGSD-----EEGCSYPPCVDGEFTC------A 2700
Query: 3954 TAQCLYASKLCDGVKDC--SGGDDEEPAFC-ENFECTEAQFKCGDKKKCIPLTSVCDKEK 3784
+C+ +++C+GV DC +G DE C N C KC C+ +CD +
Sbjct: 2701 NGRCIPQAQVCNGVNDCKDNGTSDETHERCPTNTTCPPNHLKCDRTNICVEPYWLCDGDN 2760
Query: 3783 DCDDGSDE--LNCEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDE-PDSCFG 3613
DC D SDE L+C +C + F C N +CIP +YCDG+DDC +G DE P+ C
Sbjct: 2761 DCGDNSDENPLHCAQRTCPQNSFRCPN----HRCIPATWYCDGDDDCGDGADEPPEYCKS 2816
Query: 3612 IGE-CTHEQFQCTSGKCIPKRRQCDGTLDCRDGSDE--------KGCKKECAIVCDNS-- 3466
G C + F C +G CIP+ CDG DC D SDE + C ++ C +
Sbjct: 2817 EGRTCFGDLFTCDNGNCIPRIYICDGDNDCLDNSDEDNRHQCNDRKCDEDTEFTCHENKA 2876
Query: 3465 -----CVHADDLCDGKKKCNDGSDEDE--EACVIKQLLEKENRKCG-------GFACDGI 3328
C+ +CDG C DG+DE+ + C Q ++ C G+ CD
Sbjct: 2877 WARAQCIPKKWICDGDPDCVDGADENTTLQHCPSPQPCGEDMFTCANGRCINQGWVCDHD 2936
Query: 3327 VDCEDGSDEKGCPDLECHLASNKSLICDGTIDCSSGKDENNCHNNGESNFFQC-SMQTIK 3151
DC DGSDE GK+ N+ + F C + + I+
Sbjct: 2937 NDCGDGSDE--------------------------GKNCNSQYKTCTPQEFTCQNFKCIR 2970
Query: 3150 EWQVCDGRWDCADGLDESPEMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSD 2971
CDG DC D DE C A C + + QC+D +C+ + DC D SD
Sbjct: 2971 NQYRCDGEDDCGDHSDEVG--CKKDNATCAEGKFTCNNGQCIDYH-LVCNKVPDCTDESD 3027
Query: 2970 ENPIHCK-DMCKGK--YRCTNGRCIDVSARX----XXXXXXXXXXXXXXXGAECHHF-GV 2815
E P+HC D C +RC + +C+D EC GV
Sbjct: 3028 E-PLHCNVDECAKVEIHRCGH-KCVDTLTSYYCDCNQGYKLLEDGKACADIDECIETPGV 3085
Query: 2814 CAQKCWMAFNHTA---RCHCAPGYARTKNDENECEPLSKSAEMFI-TNGNRLHLMSLENS 2647
C+Q C ++T C C Y +NDE+ C+ + I +N + MS +
Sbjct: 3086 CSQHC----SNTPGGYYCKCDERYYERQNDEHTCKRKDDTKPWLIFSNKYYVRNMSTDGH 3141
Query: 2646 QVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVDIRSKKWSDGLIGSWGEE 2467
Q +++ MN++ IDF D+ + + + D+ +K GS E+
Sbjct: 3142 QYNLIHQDL---MNVV--AIDF--DMQQHEMYF--------CDVTAKTIFKSSFGSLVED 3186
Query: 2466 -----------ESTAGL--ITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTR 2326
+ GL I D++ +Y+ + + N+ VA+ T +
Sbjct: 3187 GVRIEKTPVIKHDSHGLEGIAIDWVGRKLYWLDRHSK----------NLDVAELDGTRRK 3236
Query: 2325 TLIVNSTGTIN--SLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALV 2152
TL +G ++ ++ V P +++T+ I +DG +
Sbjct: 3237 TL---RSGVVDPRAIVVHPGIGYLYFTSWHLQAYIAKMGMDGSNFTRILTW--------- 3284
Query: 2151 ERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGY 1972
E +I P ++ +D+ +R+YW D I +GR R V + +
Sbjct: 3285 EDDIAWPNALTIDYFTDRIYWADAHLDYIAFADLEGRHRHVVLSGARVPHVFALSIFDDS 3344
Query: 1971 IYLIT-RQGSIHRMHKFTGKTNKYVQKIREVSPR-IQIRVAHPAKHTVSHITHQKNPCQS 1798
+Y +I R +KFTG V R + R + ++HP + NPC +
Sbjct: 3345 LYWTDWNLKAILRANKFTGANYTVV---RNTTHRPYDVHISHPLRQIPF-----PNPCGT 3396
Query: 1797 DYCPSNTVCVPDQDKNGILIPKCLCGPGRFFEVSTKKCMQLREKDQEASQCGDYFCYNNA 1618
NG CL P E + E+ + +C C N
Sbjct: 3397 --------------TNGGCSHLCLLAPP--LESTYLNVEGYLEEGAPSYRCA---CPNQF 3437
Query: 1617 GCS-PQKTCV--CPPGFYGRQCEINECSETCW--NGE-TCAVQEFGSTTNVVCHCPSNYT 1456
+ QKTC+ C G + + +C W +GE C + + HC +
Sbjct: 3438 YLARDQKTCIANCTSGQHRCGGDDEKCIPWFWKCDGEPDCKDRSDEPASCPARHCRAGTF 3497
Query: 1455 Q---SSC--ATNVCEGV--CG---PRGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRH 1306
Q +C +T +C+G CG +C +PCP + C+S C D W C
Sbjct: 3498 QCGNGNCTPSTTICDGTDDCGDGTDEQNC-DLPCPVSDFKCKSSGRCILD-SW---KCDG 3552
Query: 1305 KADAK--------VCYGHCFSGGACDGEGPL---NLRC-----------SCGDGLTGNRC 1192
AD K +C+ CD E N RC CGD +
Sbjct: 3553 DADCKDGSDEDPEICHKR-----TCDPETEFSCKNGRCIPKLWMCDFDNDCGDD-SDEPA 3606
Query: 1191 QNCVGHECLNG-GFCSYANSNRSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDITKP 1015
C C G C ++ R +P + G + + CP +C +
Sbjct: 3607 YMCRQRNCTTGWSRCPGQSNYRCIPKWLFCDGKDDCRDKSDELPENCP---QCNQETDFK 3663
Query: 1014 MDPITCSCEQNAAAHNTDCSPICQKQPNWCHNGGR-CLDTPGYPGKCKCLPRFAGPRCDV 838
+ C Q DC + C R C ++ KC+ + RCD
Sbjct: 3664 CNNNRCIPRQWMCDFADDCGDGSDESETQCKGKYRECSESEFRCDNGKCIS--SRWRCDH 3721
Query: 837 PVQC----DDYCTNNSKCTITNGTHFECDCKPGF---KGLRCEQETKCSECSNEAKCIKK 679
C D+Y +C NGT CK G RC+ + C + S+E C
Sbjct: 3722 EDDCGDNSDEYGCEGFQC--KNGTF---QCKSGHCIAAYFRCDGDRDCRDMSDEIGC--- 3773
Query: 678 PSGTVICQCPQGLGGEYCEKITATSCHQLECKNGGYCLKPDPSANRT 538
P+ GG YC + + +C N C+ P + T
Sbjct: 3774 --------PPRFPGGRYCPE------SRFQCAN-NLCVLPSDLCDGT 3805
Score = 202 bits (514), Expect = 9e-50
Identities = 172/581 (29%), Positives = 256/581 (43%), Gaps = 19/581 (3%)
Frame = -1
Query: 5847 CIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVACELTAVLCDGI 5668
C+P RCDG DC G DE C G RCA+ V C TA+ C+
Sbjct: 57 CVPKEKRCDGYLDCRT-----GKDEEGCP-GTACRLDQFRCANG---VRCIDTALKCNHK 107
Query: 5667 QDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASVDCVDGSDEWVEICSLSEP 5488
DC D DE C C ++ C + CI + CD DC D SDE +++ P
Sbjct: 108 NDCGDNSDEVGCNF--PPCHGGQFRCANALCIPATFHCDGYHDCSDESDE-ANCTAIACP 164
Query: 5487 PRRG-CPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSSTRNSCDQTW 5311
+ CP G NG C+ + +LCDG+RDC G DE+ CS+T SC
Sbjct: 165 DNKFLCPRGGP----NGQAKCIVKSKLCDGKRDCDDGTDEETA-----CSTT--SCPAL- 212
Query: 5310 NCQRHAGFES----CSCDDGYHLSPYDKKTCLRSPSCPK-ANCSHFCIDRRDVGHQCFCA 5146
C+ G C C G LSP D +TC C +C C + D C CA
Sbjct: 213 GCEHKCGPSLTGGVCYCPAGRTLSP-DNRTCADLDECTVWGHCDQLCTNT-DGSFSCACA 270
Query: 5145 PGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTIDGHAKATLLSNLTNGVALDYDVKSD 4966
GY L E + C E+ Y + + G + +++N T L Y +
Sbjct: 271 TGYTLMEKTR-CVAPTASSLELFFAYDRAILRMSAHGQ-DSRIIANATGASGLSYHYAKN 328
Query: 4965 LVYWTDVAH---------DGNKAGITSMSNQPNTYRVINSLPTKGIDGIAVDWLGRNIYY 4813
L+YW+D+ DG G P T+ + IA+DW+G +Y
Sbjct: 329 LLYWSDIKTRKVQSQVLVDGGFGGHDF--TLPGTWAPV---------AIAIDWVGDKLYV 377
Query: 4812 TDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAHIGRMNMDG 4633
D + V ++ GR++ ++L G+ L P + LDP L+F D +H+ R +MDG
Sbjct: 378 ADLVGQKVDVFELDGRWHAVVL-GSNLTSPADLALDPTAGLMFVAD---GSHVLRAHMDG 433
Query: 4632 SNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGSKRRMVLRG-SVRHIF 4456
++ + I+ + + + +AVD A+R+++ D+ DYI S +Y+G +R M+LRG V
Sbjct: 434 THAKSIVSEAAYK-ASGVAVDVIARRVFWCDSLLDYIESVSYEGERRVMILRGQQVPSPS 492
Query: 4455 ALAVFEDYVYWSDWHNHTIERVHKITGTNR-KVLIQDKQYR-PMGFKIVHPSLQSMGSLK 4282
LA+FE+ V+WSD I V + G++ + + + K R P VHP Q S
Sbjct: 493 RLALFENRVFWSDATKQGIMSVDRFEGSSSIQSIFKAKDIREPRALIAVHPLTQPKVS-- 550
Query: 4281 TARHPC-SQPARCDNLCIPANTPDLTTSSDNFTCMCAQGFR 4162
+PC S C +C+ S + C C G++
Sbjct: 551 ---NPCGSNNGGCSQMCV-VTAVQGAPSGLGYRCACHTGWQ 587
Score = 156 bits (395), Expect = 6e-36
Identities = 116/347 (33%), Positives = 156/347 (44%), Gaps = 12/347 (3%)
Frame = -1
Query: 6276 INCATTSQC-IHPSWKCDG--TNDCYDGSDEK-DCFVEFDATG----GSVSAPRS--CDA 6127
I AT QC +P + +G C+ G++ K +C + D T G + AP++ CDA
Sbjct: 2556 IYSATRQQCQANPCLQNNGGCAQSCHPGANGKPECKCD-DTTKPVNEGRMCAPKNHTCDA 2614
Query: 6126 KTQFACLATRTCMPKHWQCDGQPDCADGSDE--KNCDAKKCTSFEFSCESSKKCIPLEQK 5953
++F C + C+ + W CDG DC DGSDE C C + EF C + + CI K
Sbjct: 2615 -SKFYCQNGK-CISRMWSCDGDDDCGDGSDEDVNYCAFHSCAANEFRCANGR-CIFKSWK 2671
Query: 5952 CDGRRDCPDGEDEHQCETECDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDE 5773
CD DC DG DE C G F C N RCIP A C+G +DC DN S + E
Sbjct: 2672 CDHENDCKDGSDEEGCSYPPCVDG---EFTCANGRCIPQAQVCNGVNDCKDNGTSDETHE 2728
Query: 5772 VDCAAGRTSFHVPSRCADETCVVACELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWM 5593
C T +C D T + C LCDG DC D DE R C N +
Sbjct: 2729 -RCPTNTTCPPNHLKC-DRTNI--CVEPYWLCDGDNDCGDNSDENPLHCAQRTCPQNSFR 2784
Query: 5592 CDSGQCIDSGRLCDASVDCVDGSDEWVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQ 5413
C + +CI + CD DC DG+DE E C + R C + L T C+
Sbjct: 2785 CPNHRCIPATWYCDGDDDCGDGADEPPEYC---KSEGRTC---FGDLFTCDNGNCIPRIY 2838
Query: 5412 LCDGRRDCMSGIDEQCDNPQGNCSSTRNSCDQTWNCQRHAGFESCSC 5272
+CDG DC+ DE DN + C+ + D + C + + C
Sbjct: 2839 ICDGDNDCLDNSDE--DN-RHQCNDRKCDEDTEFTCHENKAWARAQC 2882
Score = 133 bits (335), Expect = 5e-29
Identities = 112/407 (27%), Positives = 190/407 (46%), Gaps = 31/407 (7%)
Frame = -1
Query: 5214 CPKANCSHFCI--DRRDVGHQCFCAPGYILSENQKDCRRNDTIEAEILMVYGHRLKLFTI 5041
C +A C H C+ G+ C C PGY L + C + A I+++ G+++
Sbjct: 1616 CKRAACQHVCLLSPSEPAGYACKCRPGYRLLPEGR-CTEEEN--AFIMLLKGNQIVDVPF 1672
Query: 5040 DG-HAKATLLS---NLTNGVALDYDVKSDLVYWT---DVAHDGNKAGITSMSNQPNTYRV 4882
+G A+++ L + G++LDYD K ++VYW D + D N + N
Sbjct: 1673 NGGDARSSGLMPVVGIEGGISLDYDRKGEMVYWVQGRDESDDENCTIYATPYGGGNRTEF 1732
Query: 4881 INSLPTKGIDG----IAVDWLGRNIYYTDR---NHDAIAVCDMRGRFNRILLKG----TP 4735
+ P G+ G IA DW+GRN+Y +R N +AI+V D + R+ ++L T
Sbjct: 1733 LG--PDTGLVGAAYTIAFDWIGRNLYVGNRLASNIEAISV-DGKVRYRTVVLANDGNRTS 1789
Query: 4734 LNDPRAIVLDPLQALVFWTD---WGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAP 4564
+ P+ + LDP +FW D +G + MDGS+ +V+ D T+++P ++ VDA
Sbjct: 1790 VAKPKQLALDPADGRLFWIDEGGFGVLTKVASAGMDGSDPRVL--DDTVQFPESITVDAE 1847
Query: 4563 AQRLYFGDAHRDYIASCNYDGSKRRMVL--RGSVRHIFALAVFEDYVYWSDWHNHTIERV 4390
+R+Y+ + S YDG+ +R +L ++ ALAV E +Y+ D + RV
Sbjct: 1848 KRRVYYSTRLPPAVLSIEYDGTGQRTILSEENAISKPRALAVLESRLYFLDPTYEKLARV 1907
Query: 4389 HKITGTNRKVLIQDKQYRPMGFKIVHPSLQSM---GSLKTARHPCSQ-PARCDNLCIPAN 4222
G N K+++ ++ P L+ M + +HPC+Q C++LC+P
Sbjct: 1908 DLPNGDNAKLILDNE-----------PDLRQMVIYRKRSSLQHPCTQNNGGCEHLCLP-- 1954
Query: 4221 TPDLTTSSDNFTCMCAQGFRSEGRSCVSECKPNDFVCT--KTYKCIS 4087
+ + C C G++ E N+ CT KT+ +S
Sbjct: 1955 -----HAGASRVCACGVGYKKE----------NEVACTPYKTFAVVS 1986
Score = 119 bits (299), Expect = 8e-25
Identities = 88/254 (34%), Positives = 107/254 (41%), Gaps = 8/254 (3%)
Frame = -1
Query: 6393 CIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDGTND 6214
C+P + RC+ DC DE GCP C L++F CA +CI + KC+ ND
Sbjct: 57 CVPKEKRCDGYLDCRTGKDEEGCPGTACR-LDQF------RCANGVRCIDTALKCNHKND 109
Query: 6213 CYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADGSDE 6034
C D SDE C F G QF C A C+P + CDG DC+D SDE
Sbjct: 110 CGDNSDEVGC--NFPPCHGG-----------QFRC-ANALCIPATFHCDGYHDCSDESDE 155
Query: 6033 KNCDAKKCTSFEFSC-----ESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNAT 5869
NC A C +F C KCI + CDG+RDC DG DE ET C + A
Sbjct: 156 ANCTAIACPDNKFLCPRGGPNGQAKCIVKSKLCDGKRDCDDGTDE---ETACSTTSCPA- 211
Query: 5868 FRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCAD-ETCVV--AC 5698
C H+C P SL C AGRT CAD + C V C
Sbjct: 212 LGC-EHKCGP----------------SLTGGVCYCPAGRTLSPDNRTCADLDECTVWGHC 254
Query: 5697 ELTAVLCDGIQDCS 5656
+ DG C+
Sbjct: 255 DQLCTNTDGSFSCA 268
Score = 116 bits (291), Expect = 6e-24
Identities = 107/383 (27%), Positives = 180/383 (46%), Gaps = 15/383 (3%)
Frame = -1
Query: 5247 YDKKTCLRSPSCPKAN--CSHFCIDRRDVGHQCFCAPGYILSENQKDCRRNDT--IEAEI 5080
Y K++ L+ P C + N C H C+ C C GY EN+ C T + +++
Sbjct: 1931 YRKRSSLQHP-CTQNNGGCEHLCLPHAGASRVCACGVGY-KKENEVACTPYKTFAVVSQL 1988
Query: 5079 LMVYGHRLKLFTIDGHAKATLLSNLTNGVALDYDVKSDLVYWTDVAHDGNKAGITSMSNQ 4900
+ G L+ T A + + + +D + +YW + + G+ GI + +
Sbjct: 1989 DVTRGFSLRDST---EAMVPIAGPGHHILHVDVLYRESWIYWVEY-NRGHWNGIFRV--R 2042
Query: 4899 PN----TYRVINSLPTKGIDGIAVDWLGRNIYYTD--RNHDAIAVCDMRGRFNRILLKGT 4738
PN + V + + + GI GIA+DW+ N+Y+T+ + + + V + G ++L+K T
Sbjct: 2043 PNGTELQHIVKDGIGSNGIRGIAIDWVAGNLYFTNVFPHENYVEVAWLDGTHRKVLVKTT 2102
Query: 4737 PLND-PRAIVLDPLQALVFWTDWGASAHIGRMNMDGSNEQVILQDRTIRWPNALAVDAPA 4561
ND PR + ++P++ L++W D+G IG+ +DGSN ++ I P L VD
Sbjct: 2103 --NDAPRELAVNPIKRLLYWIDYGQYPRIGKCFLDGSNWTPVVTS-GISNPRDLTVDMLT 2159
Query: 4560 QRLYFGDAHRDYIASCNYDGSKRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKI 4381
+Y+ D+ D I +Y G R V+R ++ + ALAVF VYW D + ++ R K
Sbjct: 2160 HDVYWVDSKLDMIQKVSYSGG-HRQVIRRNLANPMALAVFLTDVYWVDRNLASVFRASKF 2218
Query: 4380 TG-TNRKVLIQDKQYRPMGFKIVHPSLQSMGSLKTARHPCSQPAR--CDNLCIPANTPDL 4210
G + R ++ + I + Q M +PC + CD LC A PD
Sbjct: 2219 PGNSTRPERLRTNLPKLRDITIYDINSQPMDD----ANPCLRLGNGGCDQLCF-ALPPDY 2273
Query: 4209 TTSSDNFTCMCAQG-FRSEGRSC 4144
+ +F C CA G ++GR C
Sbjct: 2274 -SQKPSFRCDCAVGRLGADGRHC 2295
Score = 116 bits (290), Expect = 8e-24
Identities = 78/234 (33%), Positives = 99/234 (41%), Gaps = 16/234 (6%)
Frame = -1
Query: 3945 CLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGS 3766
C+ K CDG DC G DEE C C QF+C + +CI C+ + DC D S
Sbjct: 57 CVPKEKRCDGYLDCRTGKDEEG--CPGTACRLDQFRCANGVRCIDTALKCNHKNDCGDNS 114
Query: 3765 DELNCEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQF 3586
DE+ C C F C N + CIP F+CDG DC + DE +C I C +F
Sbjct: 115 DEVGCNFPPCHGGQFRCAN----ALCIPATFHCDGYHDCSDESDEA-NCTAIA-CPDNKF 168
Query: 3585 QCTSG------KCIPKRRQCDGTLDCRDGSDEK-GCKKEC--AIVCDNSCVHADDLCDGK 3433
C G KCI K + CDG DC DG+DE+ C A+ C++ C L G
Sbjct: 169 LCPRGGPNGQAKCIVKSKLCDGKRDCDDGTDEETACSTTSCPALGCEHKC--GPSLTGGV 226
Query: 3432 KKCNDGSDEDEEACVIKQLLEKENRKCGGF-------ACDGIVDCEDGSDEKGC 3292
C G + L +NR C CD + DGS C
Sbjct: 227 CYCPAG-----------RTLSPDNRTCADLDECTVWGHCDQLCTNTDGSFSCAC 269
Score = 111 bits (278), Expect = 2e-22
Identities = 149/597 (24%), Positives = 239/597 (39%), Gaps = 40/597 (6%)
Frame = -1
Query: 3339 CDGIVDCEDGSDEKGCPDLECHL----------ASNKSLICDGTIDCSSGKDENNCH--- 3199
CDG +DC G DE+GCP C L + +L C+ DC DE C+
Sbjct: 64 CDGYLDCRTGKDEEGCPGTACRLDQFRCANGVRCIDTALKCNHKNDCGDNSDEVGCNFPP 123
Query: 3198 -NNGESNFFQC-SMQTIKEWQVCDGRWDCADGLDE---SPEMCASRKARCFRIGYCDDKK 3034
+ G+ F+C + I CDG DC+D DE + C K C R G + +
Sbjct: 124 CHGGQ---FRCANALCIPATFHCDGYHDCSDESDEANCTAIACPDNKFLCPR-GGPNGQA 179
Query: 3033 QCLDVSTALCDGIRDCFDGSDENPIHCKDMCKG---KYRC----TNGRCIDVSARXXXXX 2875
+C+ V + LCDG RDC DG+DE C +++C T G C + R
Sbjct: 180 KCI-VKSKLCDGKRDCDDGTDEETACSTTSCPALGCEHKCGPSLTGGVCYCPAGRTLSPD 238
Query: 2874 XXXXXXXXXXXGAECHHFGVCAQKCWMAFNHTARCHCAPGYARTKNDENEC-EPLSKSAE 2698
EC +G C Q C + + C CA GY T ++ C P + S E
Sbjct: 239 NRTCADLD-----ECTVWGHCDQLCTNT-DGSFSCACATGY--TLMEKTRCVAPTASSLE 290
Query: 2697 MFITNGNRLHLMSLENSQVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNSRVD 2518
+F + MS ++ G+ + Y L+Y I +V
Sbjct: 291 LFFAYDRAILRMSAHGQDSRIIANATG------ASGLSYHY---AKNLLYWSDIKTRKV- 340
Query: 2517 IRSKKWSDGLIGSWGEEESTAG-----LITYDFMHNNVYFTESSEQNRGVL-FDRQANIY 2356
+S+ DG G G + + G I D++ + +Y + Q V D + +
Sbjct: 341 -QSQVLVDG--GFGGHDFTLPGTWAPVAIAIDWVGDKLYVADLVGQKVDVFELDGRWHAV 397
Query: 2355 VAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTG 2176
V + TS LA+DP L+F A +L A++DG
Sbjct: 398 VLGSNLTSPA-----------DLALDPTAGLMF---VADGSHVLRAHMDGTHA------- 436
Query: 2175 SQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPV 1996
K++V ++ + + +D R++W D L IE+VS++G R + + + +P
Sbjct: 437 ----KSIVSEAAYKASGVAVDVIARRVFWCDSLLDYIESVSYEGERRVMILRGQQVPSPS 492
Query: 1995 TMDVLGGYIYL--ITRQGSIHRMHKFTGKTN-KYVQKIREV-SPRIQIRVAHPAKHTVSH 1828
+ + ++ T+QG I + +F G ++ + + K +++ PR I V HP
Sbjct: 493 RLALFENRVFWSDATKQG-IMSVDRFEGSSSIQSIFKAKDIREPRALIAV-HP------- 543
Query: 1827 ITHQK--NPCQSDYCPSNTVCVPD--QDKNGILIPKCLCGPGRFFEVSTKKCMQLRE 1669
+T K NPC S+ + +CV Q L +C C G C +R+
Sbjct: 544 LTQPKVSNPCGSNNGGCSQMCVVTAVQGAPSGLGYRCACHTGWQLSKDLMNCHLVRQ 600
Score = 108 bits (271), Expect = 1e-21
Identities = 82/255 (32%), Positives = 111/255 (43%), Gaps = 23/255 (9%)
Frame = -1
Query: 6549 STRVCRPGYFNCG--------NG----LCIPEQKVCNRINDCANFADESNC---TCNENE 6415
S R C+ CG NG +C+P++K C+ DC DE C C ++
Sbjct: 29 SYRKCQTDDIRCGAPSLGVSLNGRVAEICVPKEKRCDGYLDCRTGKDEEGCPGTACRLDQ 88
Query: 6414 FRCQSGA-CIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPS 6238
FRC +G CI + +CNH DC D SDE+GC F C G CA + CI +
Sbjct: 89 FRCANGVRCIDTALKCNHKNDCGDNSDEVGCNFPPCHG-------GQFRCA-NALCIPAT 140
Query: 6237 WKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQP 6058
+ CDG +DC D SDE +C +++ P + + C+ K CDG+
Sbjct: 141 FHCDGYHDCSDESDEANC--------TAIACPDNKFLCPRGGPNGQAKCIVKSKLCDGKR 192
Query: 6057 DCADGSDEKN-CDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGE----DEHQCE--T 5899
DC DG+DE+ C C + CE KC P G CP G D C
Sbjct: 193 DCDDGTDEETACSTTSCPA--LGCE--HKCGP--SLTGGVCYCPAGRTLSPDNRTCADLD 246
Query: 5898 ECDSKGGNATFRCTN 5854
EC + G+ CTN
Sbjct: 247 EC-TVWGHCDQLCTN 260
Score = 104 bits (260), Expect = 3e-20
Identities = 74/266 (27%), Positives = 104/266 (38%), Gaps = 28/266 (10%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCT--------CNEN 6418
D+ D C C+ G F C +G CI C+ DC + +DE C C E+
Sbjct: 3727 DNSDEYGCEGFQCKNGTFQCKSGHCIAAYFRCDGDRDCRDMSDEIGCPPRFPGGRYCPES 3786
Query: 6417 EFRCQSGACIPSKARCNHMQDCNDASDEIG--CPFRNCSALNEFGMTGLINCATTSQCIH 6244
F+C + C+ C+ DC D SDE C NC L F CA +C+
Sbjct: 3787 RFQCANNLCVLPSDLCDGTDDCGDNSDEAASVCTNFNCDTLRRF------QCA-NHRCVA 3839
Query: 6243 PSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDG 6064
CDG ++C DGSDE + + + + CD TQ+ C A + C+ + CD
Sbjct: 3840 RYQICDGVDNCGDGSDENNMTL-------CAARQKPCDLYTQYQC-ANKKCIDRAQVCDY 3891
Query: 6063 QPDCADGSDEKNCDAKKCTSFEFSCESSKKCIPL------------------EQKCDGRR 5938
DC DGSDE C S C+ L +++C
Sbjct: 3892 ADDCGDGSDELGCHRTASCSALNKGGCEHHCVNLTDGYICACYAGFIIDASNKKRCTDID 3951
Query: 5937 DCPDGEDEHQCETECDSKGGNATFRC 5860
+C G H C C + N T+ C
Sbjct: 3952 ECATG--THGCSHLCTNL--NGTYEC 3973
Score = 93.6 bits (231), Expect = 6e-17
Identities = 81/248 (32%), Positives = 106/248 (42%), Gaps = 30/248 (12%)
Frame = -1
Query: 3768 SDELNCEITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQ 3589
+D++ C P NG C+PKE CDG DC G+DE + C G C +Q
Sbjct: 35 TDDIRCGA----PSLGVSLNGRVAEICVPKEKRCDGYLDCRTGKDE-EGCPGTA-CRLDQ 88
Query: 3588 FQCTSG-KCIPKRRQCDGTLDCRDGSDEKGCK-KEC---AIVCDNS-CVHADDLCDGKKK 3427
F+C +G +CI +C+ DC D SDE GC C C N+ C+ A CDG
Sbjct: 89 FRCANGVRCIDTALKCNHKNDCGDNSDEVGCNFPPCHGGQFRCANALCIPATFHCDGYHD 148
Query: 3426 CNDGSDE---DEEACVIKQLL-----EKENRKC--GGFACDGIVDCEDGSDEK------G 3295
C+D SDE AC + L KC CDG DC+DG+DE+
Sbjct: 149 CSDESDEANCTAIACPDNKFLCPRGGPNGQAKCIVKSKLCDGKRDCDDGTDEETACSTTS 208
Query: 3294 CPDLECHLASNKSLICDGTIDCSSGK----DENNCHNNGESNFF-QCSMQTIKEWQVC-- 3136
CP L C SL G C +G+ D C + E + C Q+C
Sbjct: 209 CPALGCEHKCGPSL-TGGVCYCPAGRTLSPDNRTCADLDECTVWGHCD-------QLCTN 260
Query: 3135 -DGRWDCA 3115
DG + CA
Sbjct: 261 TDGSFSCA 268
Score = 90.5 bits (223), Expect = 5e-16
Identities = 66/207 (31%), Positives = 90/207 (42%), Gaps = 14/207 (6%)
Frame = -1
Query: 6567 EDTKYCSTRVCRPGYFNCGNGL-CIPEQKVCNRINDCANFADESNCT---CNENEFRCQS 6400
+D + C CR F C NG+ CI CN NDC + +DE C C+ +FRC +
Sbjct: 74 KDEEGCPGTACRLDQFRCANGVRCIDTALKCNHKNDCGDNSDEVGCNFPPCHGGQFRCAN 133
Query: 6399 GACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDGT 6220
CIP+ C+ DC+D SDE C C G N ++CI S CDG
Sbjct: 134 ALCIPATFHCDGYHDCSDESDEANCTAIACPDNKFLCPRGGPN--GQAKCIVKSKLCDGK 191
Query: 6219 NDCYDGSDEKDCFVEFDATGGSVSAPR-SCDAKTQFA-------CLATRTCMPKHWQCDG 6064
DC DG+DE + + S P C+ K + C A RT P + C
Sbjct: 192 RDCDDGTDE-------ETACSTTSCPALGCEHKCGPSLTGGVCYCPAGRTLSPDNRTCAD 244
Query: 6063 QPDCADGSDEKNCDAKKCTSFE--FSC 5989
+C +CD + CT+ + FSC
Sbjct: 245 LDECTVWG---HCD-QLCTNTDGSFSC 267
Score = 83.6 bits (205), Expect = 6e-14
Identities = 164/728 (22%), Positives = 261/728 (35%), Gaps = 54/728 (7%)
Frame = -1
Query: 2472 EEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTIN 2293
+ E GL D++ N+Y+ +S R+ + V ++TS R ++ +
Sbjct: 675 QNEGVEGLAV-DWVSKNLYYIDS----------RKGTLNVLSTRNTSYRRTLLKNLKRPR 723
Query: 2292 SLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFE--PTSMV 2119
++ V P + I+++ I AN DG + +V RN+ P +
Sbjct: 724 AIVVHPNRGYIYFSEWDRPANISRANADGSGL-------------IVFRNLTLGWPNGLS 770
Query: 2118 LDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLIT-RQGSI 1942
+DF +R+YW D L ++ + DG D RTV L P ++ + ++Y+ R +I
Sbjct: 771 IDFREDRVYWCDALLDHVQHANLDGTDVRTVNS-RLIRHPFSIVIHEEWMYITDWRLDAI 829
Query: 1941 HRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPC--QSDYCPSNTVCV 1768
R++K G+ + + + + + ++V H V I PC + C +
Sbjct: 830 VRLNKLNGEQEEIMVREPQTNRLYGVKV---YSHGVQSI-DASQPCGVNNGGCEKLCFAL 885
Query: 1767 PDQDKNGI------------LIPKCLCGPGRFFEVSTKKCMQLREKDQEASQC---GDYF 1633
P D L+ KC C G + C+ + C D+
Sbjct: 886 PRNDTEDAAAASAGGPTSPRLVVKCGCPYGERLGDDGRSCLSDPNAEPPVQACPNTWDFT 945
Query: 1632 CYNNAGCSPQKTCVCPPGFYGRQCEINECSETCWNGETCAVQEFGSTTNVVCHC-PSNY- 1459
C NN C P K+ +C C N E TC EF + C P N+
Sbjct: 946 C-NNQRCIP-KSWICDG---DDDCLDNSDEEQNCTKPTCGTNEFQCKSG---RCIPLNFR 997
Query: 1458 --TQSSCATNVCEGVCG------PRGSCKTVPCPKDEPHCRSYSFCECDKGWTGPHCRHK 1303
++ C + E CG + +C+ C + C S + C D GP C K
Sbjct: 998 CDQENDCGDHSDEFECGNVTCAASQFACENGRCIPNIWKCDSENDCG-DGSDEGPFCAEK 1056
Query: 1302 ADAKVCY-----GHCF-SGGACDGEGPLNLRCSCGDGLTGNRCQNCVGHECLNGGF-CSY 1144
A + GHC CDG+ D ++C CL F C+
Sbjct: 1057 TCAYFQFTCPRTGHCIPQSWVCDGD---------DDCFDKQDEKDCPPITCLANQFKCA- 1106
Query: 1143 ANSNRSLPHCICPSGFTGDHCEEYLCKDACPFGSKCTYDITKP-MDPITCSCEQNAAAHN 967
L C+ E Y C D P + + ++ P M+P C+ E++
Sbjct: 1107 -----DLRQCV---------EEPYKC-DGIPDCNDGSDELGCPTMEPNQCNLEKHFR--- 1148
Query: 966 TDCSPICQKQPNWCHNGGRCLDTPGYPGKCKCLPRFAGPRCDVPVQCDDYCTNN--SKCT 793
C + G C+ + CD CDD+ SK T
Sbjct: 1149 -------------CRSSGVCIPIAWH--------------CDGSNDCDDHSDEEDCSKIT 1181
Query: 792 ITNGTHFECDCKPGFKGLRCEQETKCSECSNEA---KCIKKPSGTVICQ--CPQGLGGEY 628
NG + + K FK C+ + C + S+E+ C+ P Q CP G+ E
Sbjct: 1182 CPNGFYKCANAKCVFKAYICDGKDDCGDGSDESVEHACVTPPQRCAHGQWACP-GV-TER 1239
Query: 627 CEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGFK----GLLC-----SSNACE 475
C +T+ +C NG A T LCS G + G LC A +
Sbjct: 1240 CVNLTSVCDDVPDCPNGADEGLGCDLAQCQHQTGLCSNGCQKTPLGALCICPPGEELAPD 1299
Query: 474 NFCLHDGN 451
NF D N
Sbjct: 1300 NFTCKDLN 1307
Score = 72.4 bits (176), Expect = 1e-10
Identities = 37/101 (36%), Positives = 52/101 (50%), Gaps = 10/101 (9%)
Frame = -1
Query: 6573 DDEDTKYCSTRVCRPGYFNCGNGLCIPEQKVCNRINDCANFADESNCT---CNENEFRCQ 6403
D+ D C+ C G F C N LCIP C+ +DC++ +DE+NCT C +N+F C
Sbjct: 112 DNSDEVGCNFPPCHGGQFRCANALCIPATFHCDGYHDCSDESDEANCTAIACPDNKFLCP 171
Query: 6402 SGA------CIPSKARCNHMQDCNDASD-EIGCPFRNCSAL 6301
G CI C+ +DC+D +D E C +C AL
Sbjct: 172 RGGPNGQAKCIVKSKLCDGKRDCDDGTDEETACSTTSCPAL 212
Score = 68.2 bits (165), Expect = 3e-09
Identities = 81/327 (24%), Positives = 132/327 (39%), Gaps = 9/327 (2%)
Frame = -1
Query: 2820 GVCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSA---EMFITNGNRLHLMSLEN 2650
G C C + C C GY K +E C P A ++ +T G SL +
Sbjct: 1946 GGCEHLCLPHAGASRVCACGVGYK--KENEVACTPYKTFAVVSQLDVTRG-----FSLRD 1998
Query: 2649 SQVSVLRPVFNIKMNLIPGGIDFGYDV-FRTTLMYTV----GIGNSRVDIRSKKWSDGLI 2485
S +++ P+ PG DV +R + +Y V G N +R I
Sbjct: 1999 STEAMV-PIAG------PGHHILHVDVLYRESWIYWVEYNRGHWNGIFRVRPNGTELQHI 2051
Query: 2484 GSWGEEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNST 2305
G + I D++ N+YFT +F + + VA T + L+ +
Sbjct: 2052 VKDGIGSNGIRGIAIDWVAGNLYFTN--------VFPHENYVEVAWLDGTHRKVLVKTTN 2103
Query: 2304 GTINSLAVDPIKRLIFWTTSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTS 2125
LAV+PIKRL++W PRI LDG +V I P
Sbjct: 2104 DAPRELAVNPIKRLLYWIDYGQYPRIGKCFLDG-----------SNWTPVVTSGISNPRD 2152
Query: 2124 MVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDTPVTMDVLGGYIYLITRQ-G 1948
+ +D +YW+D I+ VS+ G R+ +R+ L + P+ + V +Y + R
Sbjct: 2153 LTVDMLTHDVYWVDSKLDMIQKVSYSGGHRQVIRR-NLAN-PMALAVFLTDVYWVDRNLA 2210
Query: 1947 SIHRMHKFTGKTNKYVQKIREVSPRIQ 1867
S+ R KF G + + +++R P+++
Sbjct: 2211 SVFRASKFPGNSTR-PERLRTNLPKLR 2236
Score = 57.4 bits (137), Expect = 5e-06
Identities = 41/148 (27%), Positives = 54/148 (35%), Gaps = 3/148 (2%)
Frame = -1
Query: 4266 CSQPARCDNLCIPANTP-DLTTSSDNFTCMCAQGFRSEGRSCVSECKPNDFVCTKTYKCI 4090
C+ RC + + N D +SD C + R + C P F C + C
Sbjct: 91 CANGVRCIDTALKCNHKNDCGDNSDEVGCNFPPCHGGQFRCANALCIPATFHCDGYHDCS 150
Query: 4089 SSWWRXXXXXXXXXXXXXGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVK 3910
E C C +F+C R N A+C+ SKLCDG +
Sbjct: 151 DE------------------SDEANCTAIACPDNKFLCPRGGPNGQAKCIVKSKLCDGKR 192
Query: 3909 DCSGGDDEEPAFCENFECTE--AQFKCG 3832
DC G DEE A C C + KCG
Sbjct: 193 DCDDGTDEETA-CSTTSCPALGCEHKCG 219
Score = 50.1 bits (118), Expect = 7e-04
Identities = 76/383 (19%), Positives = 143/383 (36%), Gaps = 16/383 (4%)
Frame = -1
Query: 2814 CAQKCWMAFNHTA--RCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLE--NS 2647
C C ++ + A C C PGY E C ++A + + GN++ + ++
Sbjct: 1621 CQHVCLLSPSEPAGYACKCRPGYRLLP--EGRCTE-EENAFIMLLKGNQIVDVPFNGGDA 1677
Query: 2646 QVSVLRPVFNIKMNLIPGGIDFGYDVFRTTLMYTVGIGNS---RVDIRSKKWSDG----L 2488
+ S L PV I+ GGI YD + + G S I + + G
Sbjct: 1678 RSSGLMPVVGIE-----GGISLDYDRKGEMVYWVQGRDESDDENCTIYATPYGGGNRTEF 1732
Query: 2487 IGSWGEEESTAGLITYDFMHNNVYFTESSEQN-RGVLFDRQANIYVAKAKDTSTRTLIVN 2311
+G A I +D++ N+Y N + D + + RT +
Sbjct: 1733 LGPDTGLVGAAYTIAFDWIGRNLYVGNRLASNIEAISVDGKVRYRTVVLANDGNRTSVAK 1792
Query: 2310 STGTINSLAVDPIKRLIFWTTSAP---VPRILSANLDGKPIAQPFKTGSQPHKALVERNI 2140
LA+DP +FW + ++ SA +DG S P +++ +
Sbjct: 1793 P----KQLALDPADGRLFWIDEGGFGVLTKVASAGMDG----------SDPR--VLDDTV 1836
Query: 2139 FEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELG-DTPVTMDVLGGYIYL 1963
P S+ +D R+Y+ L + ++ +DG +RT+ E P + VL +Y
Sbjct: 1837 QFPESITVDAEKRRVYYSTRLPPAVLSIEYDGTGQRTILSEENAISKPRALAVLESRLYF 1896
Query: 1962 ITRQGSIHRMHKFTGKTNKYVQKIREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPS 1783
+ + ++ + + I + P ++ V + + ++ H PC +
Sbjct: 1897 L--DPTYEKLARVDLPNGDNAKLILDNEPDLRQMVIYRKRSSLQH------PCTQNNGGC 1948
Query: 1782 NTVCVPDQDKNGILIPKCLCGPG 1714
+C+P + + C CG G
Sbjct: 1949 EHLCLPHAGASRV----CACGVG 1967
Score = 49.7 bits (117), Expect = 0.001
Identities = 53/232 (22%), Positives = 80/232 (33%), Gaps = 43/232 (18%)
Frame = -1
Query: 5676 DGIQDC--SDGFDEKNCASLDRQCKPNEWMCDSGQ-----------CIDSGRLCDASVDC 5536
D Q C ++G EK C +L R + +G C RL D C
Sbjct: 866 DASQPCGVNNGGCEKLCFALPRNDTEDAAAASAGGPTSPRLVVKCGCPYGERLGDDGRSC 925
Query: 5535 VDGSDEWVEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQ--CD 5362
+ + +EPP + CP+ W N C+ + +CDG DC+ DE+ C
Sbjct: 926 LSDPN--------AEPPVQACPNTWDFTCNNQR--CIPKSWICDGDDDCLDNSDEEQNCT 975
Query: 5361 NP----------QGNCSSTRNSCDQTWNCQRHAGFESC----------SCDDGYHLSPY- 5245
P G C CDQ +C H+ C +C++G +
Sbjct: 976 KPTCGTNEFQCKSGRCIPLNFRCDQENDCGDHSDEFECGNVTCAASQFACENGRCIPNIW 1035
Query: 5244 ---DKKTC----LRSPSCPKANCSHFCIDRRDVGHQCFCAPGYILSENQKDC 5110
+ C P C + C++F GH C P + + DC
Sbjct: 1036 KCDSENDCGDGSDEGPFCAEKTCAYFQFTCPRTGH---CIPQSWVCDGDDDC 1084
Score = 37.7 bits (86), Expect = 3.8
Identities = 21/71 (29%), Positives = 27/71 (37%), Gaps = 17/71 (23%)
Frame = -1
Query: 999 CSCEQNAA--AHNTDCSPICQKQPNW---------CHNGGRCLDTPGYPGK------CKC 871
CSC N +H + +C C NGG C + PG C C
Sbjct: 4293 CSCPDNTVPTSHRSTAEVVCDAPAERPRPAPRVCPCQNGGLCKEADAGPGAPSSELVCVC 4352
Query: 870 LPRFAGPRCDV 838
LP F+G C+V
Sbjct: 4353 LPEFSGTHCEV 4363
Score = 37.4 bits (85), Expect = 5.0
Identities = 51/201 (25%), Positives = 71/201 (34%), Gaps = 9/201 (4%)
Frame = -1
Query: 1023 TKPMDPITCSCEQNAAAHNTDCSPICQKQPNWCHNGGRCLDTPGYP-GKCKCLPRFAGPR 847
T P + C C + S C PN C +T + +C+P+
Sbjct: 902 TSPRLVVKCGCPYGERLGDDGRS--CLSDPNAEPPVQACPNTWDFTCNNQRCIPK--SWI 957
Query: 846 CDVPVQCDDYCTNNSKCTI-TNGTHFECDCKPGF---KGLRCEQETKCSECSNEAKCIKK 679
CD C D CT T GT+ E CK G RC+QE C + S+E +C
Sbjct: 958 CDGDDDCLDNSDEEQNCTKPTCGTN-EFQCKSGRCIPLNFRCDQENDCGDHSDEFEC--- 1013
Query: 678 PSGTVICQCPQGLGGEYCEKITATSCHQLECKNGGYCLKPDPSANRTSPTCLCSPGF-KG 502
G V C + Q C+N G C+ P+ + C G +G
Sbjct: 1014 --GNVTC-----------------AASQFACEN-GRCI---PNIWKCDSENDCGDGSDEG 1050
Query: 501 LLCSSNACENF---CLHDGNC 448
C+ C F C G+C
Sbjct: 1051 PFCAEKTCAYFQFTCPRTGHC 1071
Score = 36.6 bits (83), Expect = 8.5
Identities = 19/50 (38%), Positives = 23/50 (46%), Gaps = 4/50 (8%)
Frame = -1
Query: 1170 CLNGGFCSYANSNRSLPH----CICPSGFTGDHCEEYLCKDACPFGSKCT 1033
C NGG C A++ P C+C F+G HCE Y K GS T
Sbjct: 4328 CQNGGLCKEADAGPGAPSSELVCVCLPEFSGTHCEVYSEKILGAAGSSTT 4377